# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- HEAT PF02985.22 KKF92025.1 - 0.00051 20.1 0.1 0.065 13.5 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat CorA PF01544.18 KKF92025.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Vac14_Fab1_bd PF12755.7 KKF92025.1 - 0.14 12.8 0.1 0.31 11.7 0.1 1.6 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region RVT_1 PF00078.27 KKF92027.1 - 7.7e-08 32.1 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 KKF92028.1 - 5.4e-07 29.8 0.1 1.1e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_2 PF07727.14 KKF92029.1 - 3.3e-13 49.8 0.0 4.6e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 KKF92030.1 - 1.9e-12 47.4 0.0 2.9e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KKF92031.1 - 0.00041 20.0 1.7 0.00062 19.4 1.7 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TraG-D_C PF12696.7 KKF92031.1 - 0.019 15.0 0.1 7.7 6.5 0.0 2.5 1 1 1 2 2 2 0 TraM recognition site of TraD and TraG DUF1345 PF07077.11 KKF92031.1 - 0.034 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) Myb_DNA-bind_4 PF13837.6 KKF92031.1 - 0.93 9.9 7.8 1.3 9.4 1.2 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase_fungal PF17667.1 KKF92032.1 - 1.5e-55 188.6 0.4 1.8e-55 188.4 0.4 1.0 1 0 0 1 1 1 1 Fungal protein kinase zf-CCHC_2 PF13696.6 KKF92033.1 - 0.3 11.0 3.9 10 6.0 0.4 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 KKF92033.1 - 1.2 9.4 4.9 24 5.2 0.3 3.2 3 0 0 3 3 3 0 Zinc knuckle Hep_59 PF07052.11 KKF92034.1 - 2.5 8.9 10.7 0.09 13.5 3.9 2.1 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 Spore_coat_CotO PF14153.6 KKF92035.1 - 0.29 11.0 4.4 0.52 10.2 4.4 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Exo_endo_phos_2 PF14529.6 KKF92036.1 - 9.9e-14 51.2 1.0 2.2e-13 50.1 1.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KKF92036.1 - 3.2e-12 46.4 0.1 1.1e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3752 PF12572.8 KKF92036.1 - 0.12 12.8 4.9 11 6.5 1.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3752) TMEM214 PF10151.9 KKF92037.1 - 0.48 8.8 2.9 0.51 8.7 2.9 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF1179 PF06678.11 KKF92037.1 - 2.1 8.4 5.7 1.5 8.8 3.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) TraV PF09676.10 KKF92038.1 - 0.023 15.7 2.9 0.04 14.9 2.9 1.4 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF4939 PF16297.5 KKF92040.1 - 0.014 15.3 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) Connexin PF00029.19 KKF92042.1 - 0.0053 16.5 0.4 0.0053 16.5 0.4 1.0 1 0 0 1 1 1 1 Connexin CPSF100_C PF13299.6 KKF92042.1 - 0.0078 16.4 0.7 0.008 16.4 0.7 1.1 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal RPN2_C PF18004.1 KKF92042.1 - 0.065 13.2 7.7 0.07 13.0 7.7 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain ORC_WH_C PF18137.1 KKF92042.1 - 0.078 13.0 4.1 0.12 12.4 4.1 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal CDC45 PF02724.14 KKF92042.1 - 0.082 11.2 7.8 0.096 11.0 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 KKF92042.1 - 0.29 11.2 12.8 0.32 11.1 12.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Cnd2 PF05786.14 KKF92042.1 - 0.33 9.5 8.3 0.39 9.3 8.3 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Paf1 PF03985.13 KKF92042.1 - 0.41 9.6 9.9 0.4 9.6 9.9 1.1 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.16 KKF92042.1 - 0.74 9.0 4.7 1 8.5 4.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 KKF92042.1 - 0.8 7.7 10.8 0.91 7.6 10.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 KKF92042.1 - 1 9.8 6.3 1.3 9.5 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ferlin_C PF16165.5 KKF92042.1 - 2.7 7.9 7.2 3.5 7.5 7.2 1.2 1 0 0 1 1 1 0 Ferlin C-terminus FAM176 PF14851.6 KKF92042.1 - 2.9 7.5 6.1 2.8 7.6 5.0 1.5 2 0 0 2 2 2 0 FAM176 family NOA36 PF06524.12 KKF92042.1 - 3.2 7.0 10.6 3.4 6.9 10.6 1.1 1 0 0 1 1 1 0 NOA36 protein Pkinase_fungal PF17667.1 KKF92044.1 - 3.1e-55 187.6 0.3 4.2e-55 187.2 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase Exo_endo_phos_2 PF14529.6 KKF92045.1 - 4.1e-17 62.1 1.0 8.2e-17 61.2 0.4 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KKF92045.1 - 9.1e-14 51.5 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 KKF92045.1 - 0.0086 15.6 0.0 0.03 13.8 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family T3SS_needle_F PF09392.10 KKF92047.1 - 0.031 14.5 1.4 0.15 12.3 0.0 2.1 1 1 1 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Apidaecin PF00807.17 KKF92047.1 - 0.06 13.5 0.8 0.13 12.4 0.8 1.5 1 0 0 1 1 1 0 Apidaecin HrpB7 PF09486.10 KKF92048.1 - 0.0081 16.6 1.2 0.014 15.8 1.2 1.4 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 KKF92048.1 - 0.0089 16.6 1.8 0.011 16.3 0.5 1.8 2 0 0 2 2 2 1 SlyX FKBP_N PF01346.18 KKF92048.1 - 2.1 9.4 8.9 0.29 12.1 3.5 2.1 1 1 2 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4602 PF15375.6 KKF92049.1 - 6.2e-08 33.0 9.5 1.6e-07 31.7 9.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) PA-IIL PF07472.11 KKF92049.1 - 0.094 13.0 0.3 0.21 11.9 0.3 1.6 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) PI3K_1B_p101 PF10486.9 KKF92049.1 - 0.14 9.9 6.8 0.17 9.6 6.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NB-ARC PF00931.22 KKF92050.1 - 2.7e-11 43.1 0.0 4.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Patatin PF01734.22 KKF92050.1 - 3.9e-08 33.7 0.0 1.5e-06 28.6 0.0 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase AAA_16 PF13191.6 KKF92050.1 - 0.00021 21.7 0.2 0.001 19.5 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KKF92050.1 - 0.0041 17.1 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KKF92050.1 - 0.051 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KKF92050.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Pkinase_fungal PF17667.1 KKF92051.1 - 1.3e-62 211.9 0.1 1.6e-62 211.6 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KKF92052.1 - 3.8e-55 187.3 0.1 5.3e-55 186.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KKF92053.1 - 1.5e-51 175.5 0.7 7.9e-50 169.8 0.7 2.0 1 1 0 1 1 1 1 Fungal protein kinase RVT_2 PF07727.14 KKF92054.1 - 6.8e-08 32.4 0.3 9.4e-08 32.0 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 KKF92054.1 - 2.4e-05 24.5 0.1 7.9e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein HIM1 PF08732.10 KKF92055.1 - 3.8e-08 33.1 0.0 7.3e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.6 KKF92055.1 - 2.8e-07 30.6 0.2 4.3e-07 30.0 0.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKF92055.1 - 9.8e-07 28.5 0.0 3e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKF92055.1 - 0.0014 18.3 0.5 0.0014 18.3 0.5 2.2 2 1 0 2 2 2 1 NmrA-like family Retrotrans_gag PF03732.17 KKF92056.1 - 1.9e-07 31.3 0.0 2.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_3 PF14244.6 KKF92056.1 - 0.048 13.5 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4726 PF15855.5 KKF92056.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) Glyco_hydro_43 PF04616.14 KKF92057.1 - 1.6e-29 103.2 4.2 2.1e-29 102.8 4.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Retrotrans_gag PF03732.17 KKF92058.1 - 2.1e-07 31.1 0.2 6.4e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_2 PF07727.14 KKF92059.1 - 2.1e-24 86.5 0.2 7.5e-15 55.2 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KKF92059.1 - 6.5e-09 36.0 0.1 3.7e-08 33.6 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain He_PIG_assoc PF10632.9 KKF92060.1 - 0.15 11.7 0.0 0.43 10.3 0.0 1.8 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Foie-gras_1 PF11817.8 KKF92062.1 - 0.062 12.9 0.1 0.062 12.9 0.1 2.2 2 0 0 2 2 2 0 Foie gras liver health family 1 Y1_Tnp PF01797.16 KKF92062.1 - 0.093 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Transposase IS200 like Cas_Csy2 PF09614.10 KKF92063.1 - 0.068 12.5 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) ApbA_C PF08546.11 KKF92064.1 - 3.2e-23 82.3 0.0 4.9e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KKF92064.1 - 9.9e-15 54.5 0.0 3.4e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pox_A11 PF05061.13 KKF92065.1 - 0.055 12.7 0.2 0.061 12.6 0.2 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein zf-CCHC PF00098.23 KKF92066.1 - 0.00027 20.9 0.8 0.00058 19.8 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle APG17 PF04108.12 KKF92066.1 - 0.00036 19.8 0.7 0.00047 19.4 0.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 Pkinase_fungal PF17667.1 KKF92067.1 - 5.1e-48 163.8 1.4 2.5e-46 158.3 1.4 2.1 1 1 0 1 1 1 1 Fungal protein kinase IFRD PF05004.13 KKF92068.1 - 0.00071 18.8 1.0 0.037 13.1 0.0 2.1 1 1 1 2 2 2 2 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 KKF92068.1 - 0.0016 18.5 0.6 2.4 8.7 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat CorA PF01544.18 KKF92068.1 - 0.025 13.9 0.1 0.084 12.2 0.0 1.8 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Glyco_hydro_39 PF01229.17 KKF92068.1 - 0.026 13.1 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 TetR_C_12 PF16914.5 KKF92068.1 - 0.1 12.7 0.6 0.27 11.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial transcriptional repressor C-terminal Pkinase_fungal PF17667.1 KKF92069.1 - 4.5e-56 190.4 0.1 6e-56 190.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Mac PF12464.8 KKF92070.1 - 3e-10 40.2 0.4 4.3e-10 39.7 0.4 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase HTH_28 PF13518.6 KKF92070.1 - 0.17 12.0 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Retrotrans_gag PF03732.17 KKF92071.1 - 0.0032 17.7 0.0 0.0054 17.0 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Phosphodiest PF01663.22 KKF92072.1 - 7.4e-94 315.3 0.2 1.1e-93 314.7 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKF92072.1 - 0.0055 16.1 0.0 0.09 12.2 0.0 2.2 2 0 0 2 2 2 1 Sulfatase BAR_2 PF10455.9 KKF92072.1 - 0.0061 15.7 0.2 0.01 15.0 0.2 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking OMP_b-brl_2 PF13568.6 KKF92073.1 - 0.061 13.3 3.9 0.44 10.5 2.1 2.0 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain KRTAP PF11759.8 KKF92073.1 - 0.25 11.9 9.4 0.41 11.2 9.4 1.4 1 0 0 1 1 1 0 Keratin-associated matrix Myb_DNA-bind_6 PF13921.6 KKF92074.1 - 3.5e-12 46.4 1.0 2.5e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKF92074.1 - 1.5e-09 37.9 0.3 0.00019 21.5 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain AtuA PF07287.11 KKF92074.1 - 0.18 10.5 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA RVT_1 PF00078.27 KKF92075.1 - 3e-27 95.6 0.0 4.7e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2497 PF10691.9 KKF92075.1 - 0.2 12.1 0.3 0.69 10.4 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) TauD PF02668.16 KKF92076.1 - 4e-24 85.9 0.0 7.1e-24 85.0 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KKF92076.1 - 0.00058 19.1 0.0 0.00094 18.4 0.0 1.2 1 0 0 1 1 1 1 CsiD Patatin PF01734.22 KKF92077.1 - 6.1e-15 55.9 0.5 8e-09 36.0 0.3 2.4 1 1 1 2 2 2 2 Patatin-like phospholipase NACHT PF05729.12 KKF92077.1 - 2.4e-08 34.1 0.0 4.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KKF92077.1 - 0.0025 18.2 0.0 0.012 15.9 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_11 PF13086.6 KKF92077.1 - 0.037 13.8 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain GvpD PF07088.11 KKF92077.1 - 0.079 11.6 0.0 0.18 10.4 0.0 1.6 2 0 0 2 2 2 0 GvpD gas vesicle protein TsaE PF02367.17 KKF92077.1 - 0.081 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PAP_assoc PF03828.19 KKF92077.1 - 0.1 12.8 0.1 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 Cid1 family poly A polymerase DUF2075 PF09848.9 KKF92077.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KKF92077.1 - 0.18 12.2 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Pkinase_fungal PF17667.1 KKF92080.1 - 1.2e-59 202.2 0.0 1.6e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF4939 PF16297.5 KKF92082.1 - 1e-10 41.5 0.0 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 KKF92082.1 - 0.09 13.1 0.0 0.17 12.1 0.0 1.5 1 1 0 1 1 1 0 Retrotransposon gag protein ORF6N PF10543.9 KKF92082.1 - 0.098 12.9 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 ORF6N domain Glyco_transf_8 PF01501.20 KKF92083.1 - 0.0072 15.9 0.3 0.0072 15.9 0.3 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KKF92083.1 - 0.02 14.3 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative RNase_PH PF01138.21 KKF92085.1 - 7.6e-10 39.4 0.0 1.4e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKF92085.1 - 0.0032 17.5 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Retrotrans_gag PF03732.17 KKF92086.1 - 6.9e-05 23.0 1.6 0.11 12.8 0.0 3.7 2 1 1 3 3 3 2 Retrotransposon gag protein Atg14 PF10186.9 KKF92086.1 - 6.6 5.7 7.5 1.6 7.7 3.8 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RT_RNaseH PF17917.1 KKF92087.1 - 3.2e-36 123.8 0.0 5.1e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KKF92087.1 - 1.8e-22 79.3 0.0 3.2e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KKF92087.1 - 2.5e-18 65.9 0.0 5.1e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KKF92087.1 - 1.5e-07 31.5 0.1 3.4e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RHH_5 PF07878.11 KKF92087.1 - 0.047 13.6 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF4982 PF16355.5 KKF92087.1 - 0.088 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) Retrotran_gag_2 PF14223.6 KKF92088.1 - 0.046 13.4 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KKF92088.1 - 0.15 11.8 5.0 0.32 10.8 5.0 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC PF00098.23 KKF92088.1 - 2.2 8.5 6.5 6.8 7.0 3.8 2.6 2 0 0 2 2 2 0 Zinc knuckle NB-ARC PF00931.22 KKF92089.1 - 3e-12 46.3 0.1 4.5e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain Patatin PF01734.22 KKF92089.1 - 1.9e-05 25.0 0.1 0.0052 17.0 0.1 2.7 2 1 1 3 3 3 1 Patatin-like phospholipase NACHT PF05729.12 KKF92089.1 - 0.00016 21.7 0.0 0.00031 20.7 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KKF92089.1 - 0.00026 21.4 0.3 0.0017 18.8 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 KKF92089.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KKF92089.1 - 0.018 15.4 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KKF92089.1 - 0.018 14.8 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase PF06745.13 KKF92089.1 - 0.09 12.1 0.1 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 KaiC DUF5553 PF17707.1 KKF92089.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5553) RVT_1 PF00078.27 KKF92091.1 - 6.8e-24 84.6 0.0 1.2e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KKF92091.1 - 0.00013 21.8 1.3 0.00028 20.8 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 KKF92091.1 - 0.0023 18.2 0.7 0.0046 17.2 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 KKF92091.1 - 0.021 14.6 2.6 0.05 13.4 2.6 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 KKF92091.1 - 0.074 12.8 2.7 1.5 8.6 1.8 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger BST2 PF16716.5 KKF92091.1 - 0.2 12.2 2.8 0.61 10.7 1.6 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Tup_N PF08581.10 KKF92091.1 - 1.7 9.0 4.5 1.3 9.3 1.6 2.1 2 0 0 2 2 2 0 Tup N-terminal RT_RNaseH PF17917.1 KKF92092.1 - 7.7e-24 84.0 0.0 3.1e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KKF92092.1 - 3.3e-20 72.0 0.0 1.2e-19 70.2 0.0 2.0 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KKF92092.1 - 4.8e-20 71.9 0.0 4.8e-19 68.7 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KKF92092.1 - 1.7e-06 28.0 0.7 3.1e-06 27.2 0.7 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KKF92092.1 - 8.9e-05 22.2 0.0 0.00037 20.2 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 KKF92092.1 - 0.00054 20.0 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain SMN PF06003.12 KKF92092.1 - 0.85 8.8 5.6 1.5 8.0 5.6 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-C2H2 PF00096.26 KKF92093.1 - 1.3e-16 60.0 23.2 0.00065 20.0 0.4 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKF92093.1 - 5.4e-12 45.6 27.8 1.7e-06 28.1 0.2 5.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_8 PF15909.5 KKF92093.1 - 2.8e-05 24.3 6.4 0.00047 20.4 2.1 3.4 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 KKF92093.1 - 0.012 16.4 34.4 0.1 13.5 0.3 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KKF92093.1 - 0.017 15.2 5.0 0.63 10.2 0.2 3.0 2 1 1 3 3 3 0 Aberrant zinc-finger IBR PF01485.21 KKF92093.1 - 5.3 7.3 7.6 12 6.2 4.9 2.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain PI-PLC-X PF00388.19 KKF92094.1 - 3.1e-06 26.8 0.0 2.4e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Abhydrolase_1 PF00561.20 KKF92096.1 - 1.5e-18 67.4 0.4 1.8e-14 54.0 0.5 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKF92096.1 - 1.3e-10 40.9 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKF92096.1 - 6e-10 40.1 0.0 1.1e-09 39.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KKF92096.1 - 0.00023 21.3 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain HET PF06985.11 KKF92097.1 - 4.9e-09 36.7 5.7 8.4e-09 35.9 1.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Retrotrans_gag PF03732.17 KKF92098.1 - 0.0001 22.5 0.1 0.00022 21.4 0.0 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein TAF1_subA PF14929.6 KKF92098.1 - 0.065 12.6 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A Glyco_hydro_18 PF00704.28 KKF92099.1 - 8e-58 196.6 0.0 1e-57 196.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CFEM PF05730.11 KKF92100.1 - 5.2e-10 39.3 5.8 1.1e-09 38.2 5.8 1.6 1 0 0 1 1 1 1 CFEM domain FSA_C PF10479.9 KKF92100.1 - 0.59 8.2 18.3 0.24 9.5 16.3 1.3 1 1 0 1 1 1 0 Fragile site-associated protein C-terminus RSN1_7TM PF02714.15 KKF92102.1 - 7.9e-25 87.7 11.8 1.1e-24 87.2 11.8 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Deltameth_res PF16020.5 KKF92102.1 - 0.046 13.6 0.3 1.1 9.2 0.3 2.4 2 0 0 2 2 2 0 Deltamethrin resistance DUF4131 PF13567.6 KKF92102.1 - 9.3 5.9 15.6 0.49 10.0 4.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) GTP_cyclohydro2 PF00925.20 KKF92103.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II AMA-1 PF02430.15 KKF92103.1 - 0.064 12.2 0.0 0.072 12.0 0.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 RSN1_7TM PF02714.15 KKF92104.1 - 0.00015 21.2 0.2 0.00024 20.5 0.2 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate DUF3456 PF11938.8 KKF92104.1 - 0.11 13.1 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Exo_endo_phos_2 PF14529.6 KKF92105.1 - 1.8e-16 60.1 0.9 5.7e-16 58.4 0.1 2.4 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase LIFR_N PF18207.1 KKF92105.1 - 0.046 14.1 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain Ecm29 PF13001.7 KKF92106.1 - 6.7e-91 305.4 1.4 1.5e-72 244.9 0.0 2.7 1 1 1 2 2 2 2 Proteasome stabiliser KH_dom-like PF14714.6 KKF92106.1 - 0.063 13.6 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal DUF1759 PF03564.15 KKF92107.1 - 0.12 12.3 0.7 3.6 7.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) GARP PF16731.5 KKF92107.1 - 0.37 10.4 10.0 3.7 7.2 0.2 3.7 2 1 1 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma RVT_2 PF07727.14 KKF92108.1 - 3e-30 105.6 0.0 8.4e-29 100.9 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 KKF92108.1 - 0.055 13.3 0.1 0.16 11.8 0.1 1.9 1 1 0 1 1 1 0 Reverse transcriptase-like HEAT_EZ PF13513.6 KKF92110.1 - 0.00028 21.3 0.1 4.4 7.9 0.0 4.2 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 KKF92110.1 - 0.00032 20.7 3.4 0.11 12.8 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat IFRD PF05004.13 KKF92110.1 - 0.0095 15.1 0.7 0.16 11.0 0.0 2.2 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) MINDY_DUB PF04424.13 KKF92112.1 - 4.5e-19 68.6 0.0 7.2e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Retrotran_gag_2 PF14223.6 KKF92113.1 - 0.00011 21.9 0.3 0.00034 20.3 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type tRNA-synt_1b PF00579.25 KKF92114.1 - 1.1e-53 182.5 0.0 1.5e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PepSY_like PF11396.8 KKF92114.1 - 0.039 14.5 0.0 0.08 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative beta-lactamase-inhibitor-like, PepSY-like Amidase PF01425.21 KKF92115.1 - 7.2e-39 134.0 0.0 7.1e-30 104.3 0.1 3.0 2 1 1 3 3 3 3 Amidase DAP PF15228.6 KKF92116.1 - 2.6 9.3 6.0 2.2 9.5 0.4 3.0 3 0 0 3 3 3 0 Death-associated protein DcpS PF05652.12 KKF92117.1 - 9.3e-36 122.8 0.0 1.6e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KKF92117.1 - 8.9e-31 106.7 0.0 1.4e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GILT PF03227.16 KKF92118.1 - 2.7e-18 66.2 0.0 4.2e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Retrotran_gag_2 PF14223.6 KKF92119.1 - 6.6e-05 22.6 0.7 0.0027 17.4 0.0 3.1 3 1 0 3 3 3 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 KKF92119.1 - 0.00031 21.0 0.0 0.0024 18.1 0.0 2.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF2730 PF10805.8 KKF92119.1 - 0.0037 17.3 1.0 0.0037 17.3 1.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2730) zf-CCHC PF00098.23 KKF92119.1 - 0.013 15.5 0.4 0.026 14.6 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KKF92119.1 - 0.062 13.0 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger RSN1_7TM PF02714.15 KKF92120.1 - 9.4e-63 212.1 23.1 1.1e-62 211.8 23.1 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate DUF4131 PF13567.6 KKF92120.1 - 1.9 8.1 6.0 0.66 9.6 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4451 PF14616.6 KKF92121.1 - 3.1e-25 88.8 0.1 6.2e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Retrotrans_gag PF03732.17 KKF92124.1 - 5.6e-07 29.7 0.0 6.6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein Patatin PF01734.22 KKF92125.1 - 5.4e-05 23.5 0.1 0.0063 16.7 0.1 2.3 1 1 1 2 2 2 1 Patatin-like phospholipase NB-ARC PF00931.22 KKF92125.1 - 0.00024 20.4 0.0 0.0004 19.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KKF92125.1 - 0.0014 19.0 0.1 0.0049 17.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 KKF92125.1 - 0.012 15.3 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KKF92125.1 - 0.012 15.9 0.0 0.048 13.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KKF92125.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KKF92125.1 - 0.17 11.6 0.3 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Pro_CA PF00484.19 KKF92126.1 - 2.7e-50 170.7 0.1 3.5e-50 170.3 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Pkinase_fungal PF17667.1 KKF92127.1 - 1.9e-117 392.5 0.0 2.3e-117 392.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KKF92127.1 - 1.2e-06 28.2 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain zf-CCHC_2 PF13696.6 KKF92128.1 - 0.02 14.7 0.8 0.049 13.5 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 KKF92129.1 - 5.5e-27 94.7 0.0 8.7e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 KKF92129.1 - 0.0025 18.1 0.0 0.0047 17.2 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein NACHT PF05729.12 KKF92131.1 - 2.9e-21 76.1 0.0 6.6e-21 74.9 0.0 1.6 2 0 0 2 2 2 1 NACHT domain Patatin PF01734.22 KKF92131.1 - 2.8e-15 57.1 0.1 1.3e-14 54.9 0.1 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase AAA_19 PF13245.6 KKF92131.1 - 0.00038 20.8 0.0 0.003 17.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKF92131.1 - 0.0013 19.1 0.0 0.0049 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KKF92131.1 - 0.018 14.8 0.0 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KKF92131.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKF92131.1 - 0.079 13.3 0.1 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.14 KKF92131.1 - 0.11 11.8 0.4 2.9 7.1 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain TsaE PF02367.17 KKF92131.1 - 0.15 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RVT_2 PF07727.14 KKF92132.1 - 5.7e-24 85.1 0.0 8.3e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L23eN PF03939.13 KKF92132.1 - 0.026 14.7 0.1 0.064 13.5 0.1 1.7 1 1 0 1 1 1 0 Ribosomal protein L23, N-terminal domain RVT_1 PF00078.27 KKF92133.1 - 0.0056 16.2 0.0 0.032 13.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ELH PF02323.15 KKF92133.1 - 0.15 11.4 1.0 6.3 6.1 0.1 2.3 2 0 0 2 2 2 0 Egg-laying hormone precursor RVT_1 PF00078.27 KKF92134.1 - 6.7e-07 29.0 0.0 2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Jacalin PF01419.17 KKF92135.1 - 1.8e-07 31.1 0.3 4e-07 30.0 0.3 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain DUF4776 PF16003.5 KKF92137.1 - 0.035 13.1 6.0 0.42 9.5 6.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4776) Spore_YpjB PF09577.10 KKF92137.1 - 0.055 13.3 2.8 0.13 12.1 1.9 1.9 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) RVT_2 PF07727.14 KKF92138.1 - 1.8e-19 70.4 1.3 1.6e-11 44.3 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KKF92138.1 - 0.00019 21.1 1.9 0.00025 20.7 0.2 2.1 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type NACHT_N PF17100.5 KKF92139.1 - 7.2e-51 173.2 8.5 9.9e-33 113.8 0.0 3.4 3 1 1 4 4 4 2 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KKF92139.1 - 1.1e-18 67.7 0.0 4.3e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 KKF92139.1 - 0.0052 17.1 0.0 0.042 14.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain ParE_toxin PF05016.15 KKF92139.1 - 0.02 15.5 0.4 1.7 9.3 0.1 3.2 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE TsaE PF02367.17 KKF92139.1 - 0.023 14.7 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KKF92139.1 - 0.028 14.4 0.6 0.4 10.7 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit TipAS PF07739.13 KKF92139.1 - 0.032 14.8 4.0 0.086 13.4 3.0 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain AAA_22 PF13401.6 KKF92139.1 - 0.073 13.3 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Glyco_hydro_4 PF02056.16 KKF92139.1 - 0.15 11.6 0.6 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase LAG1-DNAbind PF09271.11 KKF92139.1 - 0.28 11.8 1.8 0.76 10.4 1.8 1.7 1 0 0 1 1 1 0 LAG1, DNA binding AAA_11 PF13086.6 KKF92139.1 - 0.3 10.8 6.3 0.56 9.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF1664 PF07889.12 KKF92139.1 - 2.3 8.2 5.9 1 9.4 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PI-PLC-X PF00388.19 KKF92140.1 - 4.6e-07 29.5 0.0 8.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Rep_fac_C PF08542.11 KKF92140.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Replication factor C C-terminal domain LRR_4 PF12799.7 KKF92141.1 - 8.1e-05 22.9 0.4 6.8 7.3 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KKF92141.1 - 0.00018 21.3 1.3 0.0004 20.2 1.3 1.6 1 0 0 1 1 1 1 F-box-like NACHT_N PF17100.5 KKF92142.1 - 5.4e-65 219.4 2.1 9.5e-65 218.5 2.1 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KKF92142.1 - 4.8e-14 52.6 0.1 1.4e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 KKF92142.1 - 0.0014 18.6 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE F-box-like PF12937.7 KKF92143.1 - 5e-07 29.5 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKF92143.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 KKF92143.1 - 0.028 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain FCD PF07729.12 KKF92144.1 - 0.037 14.5 0.1 0.14 12.6 0.1 2.0 1 0 0 1 1 1 0 FCD domain Neuropep_like PF15161.6 KKF92144.1 - 0.062 13.0 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Neuropeptide-like NOA36 PF06524.12 KKF92145.1 - 0.03 13.6 22.1 0.034 13.5 22.1 1.1 1 0 0 1 1 1 0 NOA36 protein RNA_pol_Rpc4 PF05132.14 KKF92145.1 - 0.12 12.8 2.3 0.11 12.9 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 KKF92145.1 - 0.14 10.5 21.9 0.16 10.3 21.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 KKF92145.1 - 0.17 10.8 3.2 0.14 11.1 3.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 KKF92145.1 - 0.8 8.4 5.9 0.97 8.1 5.9 1.2 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 KKF92145.1 - 1 7.7 5.9 1.1 7.6 5.9 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4820 PF16091.5 KKF92145.1 - 1.1 8.6 8.7 1.2 8.4 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) zf-CCHC_2 PF13696.6 KKF92146.1 - 0.042 13.7 2.3 0.078 12.8 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle ARD PF03079.14 KKF92147.1 - 3.3e-46 157.3 0.1 3.9e-46 157.1 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KKF92147.1 - 1.2e-07 31.3 0.1 2e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KKF92147.1 - 0.0004 20.3 0.0 0.00057 19.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Glyco_transf_8 PF01501.20 KKF92149.1 - 0.022 14.3 0.2 0.022 14.3 0.2 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KKF92149.1 - 0.076 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Rsm22 PF09243.10 KKF92150.1 - 1.5e-08 34.2 0.1 2.9e-08 33.3 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 NACHT_N PF17100.5 KKF92151.1 - 1.5e-68 231.0 0.6 3.3e-68 229.8 0.6 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KKF92151.1 - 5.1e-19 68.8 0.1 2.1e-18 66.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 KKF92151.1 - 0.0035 17.7 0.0 0.016 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKF92151.1 - 0.0086 16.4 0.0 0.18 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KKF92151.1 - 0.016 15.2 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KKF92151.1 - 0.016 15.1 0.0 0.052 13.5 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ResIII PF04851.15 KKF92151.1 - 0.028 14.4 0.3 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KKF92151.1 - 0.037 13.8 3.9 0.22 11.3 0.0 2.5 1 1 1 2 2 2 0 AAA domain DASH_Dam1 PF08653.10 KKF92151.1 - 0.32 10.8 1.9 1.9 8.3 0.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 Homeobox_KN PF05920.11 KKF92152.1 - 3.2e-20 71.7 0.7 8.2e-20 70.4 0.7 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KKF92152.1 - 2.3e-07 30.6 1.8 2.3e-07 30.6 1.8 1.7 2 0 0 2 2 2 1 Homeodomain PI-PLC-X PF00388.19 KKF92154.1 - 2.3e-08 33.7 0.0 4.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Pkinase PF00069.25 KKF92155.1 - 1.2e-08 34.7 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KKF92155.1 - 6.6e-06 25.2 0.0 6.6e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KKF92155.1 - 0.00013 21.3 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KKF92155.1 - 0.001 18.7 0.3 0.0016 18.1 0.3 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KKF92155.1 - 0.0011 19.0 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKF92155.1 - 0.15 11.6 0.1 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family DUF4939 PF16297.5 KKF92156.1 - 0.0024 17.7 0.0 0.0068 16.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 KKF92156.1 - 0.0073 16.6 0.0 0.029 14.6 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH PF17917.1 KKF92157.1 - 9.1e-36 122.3 0.0 1.8e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KKF92157.1 - 1.9e-32 111.3 0.0 3.6e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KKF92157.1 - 1.2e-26 93.7 0.0 2e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KKF92157.1 - 7.7e-20 70.8 0.0 1.8e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KKF92157.1 - 9e-07 29.0 0.1 1.8e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger DUF4939 PF16297.5 KKF92157.1 - 6.4e-06 26.0 0.0 4.5e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 KKF92157.1 - 0.002 18.4 0.0 0.015 15.5 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 KKF92157.1 - 0.92 9.7 5.9 0.14 12.3 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle Arylesterase PF01731.20 KKF92159.1 - 0.0001 22.4 0.1 0.00025 21.2 0.1 1.7 1 0 0 1 1 1 1 Arylesterase DUF1418 PF07214.12 KKF92159.1 - 0.16 11.8 0.2 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) RSS_P20 PF11757.8 KKF92161.1 - 1.5 9.3 7.0 7.2 7.1 0.6 2.4 1 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain PIG-X PF08320.12 KKF92162.1 - 2.2e-65 220.5 0.0 2.9e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 DUF2722 PF10846.8 KKF92163.1 - 2e-06 27.0 2.1 3.2e-06 26.4 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF5308 PF17233.2 KKF92163.1 - 0.001 19.4 0.1 0.0027 18.0 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Fungal_trans PF04082.18 KKF92163.1 - 0.005 15.9 0.3 0.005 15.9 0.3 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Macoilin PF09726.9 KKF92163.1 - 0.0053 15.4 1.3 0.0083 14.7 1.3 1.3 1 0 0 1 1 1 1 Macoilin family NPR3 PF03666.13 KKF92163.1 - 0.017 13.9 2.0 0.027 13.3 2.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PIP5K PF01504.18 KKF92163.1 - 0.041 13.1 2.8 0.076 12.2 2.8 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Roughex PF06020.11 KKF92163.1 - 0.047 12.8 3.3 0.081 12.0 3.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein RSRP PF17069.5 KKF92163.1 - 0.09 12.3 8.4 0.2 11.2 8.4 1.5 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 FmiP_Thoc5 PF09766.9 KKF92163.1 - 0.11 11.7 7.5 0.2 10.9 7.5 1.3 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 SR-25 PF10500.9 KKF92163.1 - 0.18 11.4 12.9 0.39 10.3 12.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 KKF92163.1 - 0.22 11.5 21.2 0.046 13.7 12.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 KKF92163.1 - 0.39 10.7 7.4 0.75 9.8 7.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Baculo_PP31 PF05311.11 KKF92163.1 - 0.55 9.7 7.9 0.85 9.1 7.9 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CCDC53 PF10152.9 KKF92163.1 - 0.58 10.6 8.9 0.068 13.6 4.1 1.8 2 0 0 2 2 1 0 Subunit CCDC53 of WASH complex RP-C_C PF11800.8 KKF92163.1 - 0.68 10.0 7.5 1 9.4 6.0 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region Tim54 PF11711.8 KKF92163.1 - 0.71 8.6 3.3 1.1 8.0 3.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CSG2 PF16965.5 KKF92163.1 - 0.94 8.3 4.0 1.7 7.5 4.0 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator DUF1840 PF08895.11 KKF92163.1 - 1.6 9.1 7.3 1.5 9.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Pex14_N PF04695.13 KKF92163.1 - 1.7 9.3 17.0 0.26 11.9 11.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kei1 PF08552.11 KKF92163.1 - 2.1 8.2 6.1 6.1 6.7 6.1 1.7 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 CCDC106 PF15794.5 KKF92163.1 - 3.2 7.4 11.0 6.2 6.5 11.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Neur_chan_memb PF02932.16 KKF92163.1 - 3.6 7.6 5.4 7.4 6.5 5.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KKF92163.1 - 4 6.1 13.2 33 3.1 14.1 1.8 2 0 0 2 2 2 0 Presenilin MID_MedPIWI PF18296.1 KKF92163.1 - 6.3 6.5 14.5 4.4 7.0 11.8 1.9 2 0 0 2 2 2 0 MID domain of medPIWI DUF4820 PF16091.5 KKF92163.1 - 8.3 5.7 8.4 18 4.6 8.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CPSF100_C PF13299.6 KKF92163.1 - 9 6.4 7.0 28 4.8 7.0 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PI-PLC-X PF00388.19 KKF92164.1 - 1e-08 34.8 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Rep_fac_C PF08542.11 KKF92164.1 - 0.0035 17.7 0.0 0.008 16.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain zf-CCHC PF00098.23 KKF92165.1 - 0.042 13.9 3.6 0.074 13.2 3.6 1.4 1 0 0 1 1 1 0 Zinc knuckle T3SS_needle_F PF09392.10 KKF92165.1 - 0.095 12.9 0.1 4.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Retrotran_gag_2 PF14223.6 KKF92165.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type PI-PLC-X PF00388.19 KKF92166.1 - 3.1e-12 46.3 0.0 5.8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-X PF00388.19 KKF92167.1 - 1.7e-09 37.4 0.0 2.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain MdcG PF10620.9 KKF92168.1 - 0.03 14.1 0.8 0.038 13.8 0.8 1.1 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Retrotran_gag_2 PF14223.6 KKF92169.1 - 0.0032 17.1 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KKF92169.1 - 0.017 14.8 0.5 0.031 14.0 0.5 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger MADF_DNA_bdg PF10545.9 KKF92169.1 - 0.74 10.2 6.0 4.9 7.5 0.2 3.1 2 2 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like STE PF02200.16 KKF92170.1 - 2.4e-56 188.9 0.1 3.8e-56 188.2 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor Jacalin PF01419.17 KKF92171.1 - 8.6e-05 22.5 0.9 8.6e-05 22.5 0.9 2.0 2 0 0 2 2 2 1 Jacalin-like lectin domain LIM_bind PF01803.16 KKF92172.1 - 4.4e-54 183.6 1.9 4.4e-54 183.6 1.9 5.5 3 1 1 4 4 4 1 LIM-domain binding protein Nop14 PF04147.12 KKF92173.1 - 1.3e-280 933.6 27.4 1.5e-280 933.3 27.4 1.0 1 0 0 1 1 1 1 Nop14-like family Imm42 PF15593.6 KKF92173.1 - 10 6.6 8.2 0.74 10.3 0.4 3.2 4 1 1 5 5 5 0 Immunity protein 42 zf-C3HC4_3 PF13920.6 KKF92174.1 - 2.4e-06 27.3 9.3 2.4e-06 27.3 9.3 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PLU-1 PF08429.11 KKF92174.1 - 0.026 13.7 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 PLU-1-like protein zf-RING_2 PF13639.6 KKF92174.1 - 2.8 8.4 23.0 0.35 11.2 11.6 2.7 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 KKF92174.1 - 6.2 6.7 22.7 0.14 12.1 12.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_18 PF00704.28 KKF92175.1 - 2e-11 44.2 0.1 2.3e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KKF92176.1 - 5.2e-66 223.5 0.0 7.7e-55 186.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKF92176.1 - 8.3e-29 99.8 113.7 2.9e-07 30.8 22.5 4.6 4 0 0 4 4 4 4 Chitin recognition protein Chitin_bind_1 PF00187.19 KKF92177.1 - 2.1e-60 200.9 233.9 5.7e-08 33.1 20.2 8.6 8 0 0 8 8 8 8 Chitin recognition protein Glyco_hydro_18 PF00704.28 KKF92177.1 - 4.6e-56 190.8 0.0 6.3e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GDPD_2 PF13653.6 KKF92179.1 - 0.00083 19.7 0.5 0.002 18.5 0.2 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CCDC53 PF10152.9 KKF92180.1 - 0.37 11.2 16.4 0.27 11.6 12.0 2.5 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Spore_GerAC PF05504.11 KKF92180.1 - 0.39 10.9 5.3 1.4 9.1 5.1 1.9 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Ebp2 PF05890.12 KKF92181.1 - 1e-89 300.7 12.5 1e-89 300.7 12.5 2.2 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Cupredoxin_1 PF13473.6 KKF92182.1 - 0.043 13.9 0.2 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 Cupredoxin-like domain Cu_bind_like PF02298.17 KKF92182.1 - 0.057 13.4 0.1 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain PepSY_2 PF13670.6 KKF92182.1 - 0.065 13.3 0.1 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Chromo PF00385.24 KKF92183.1 - 4.4e-06 26.5 1.8 1.4e-05 24.9 0.2 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SelB-wing_2 PF09106.11 KKF92183.1 - 0.03 14.5 0.1 0.1 12.8 0.1 2.0 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Glyco_hydro_16 PF00722.21 KKF92184.1 - 3.1e-07 30.1 0.0 3.4e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DFP PF04127.15 KKF92185.1 - 4.2e-15 56.1 0.0 1.5e-06 28.2 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Iwr1 PF08574.10 KKF92187.1 - 9.1e-09 36.2 9.5 9.1e-09 36.2 9.5 2.4 2 0 0 2 2 2 1 Transcription factor Iwr1 WD40 PF00400.32 KKF92188.1 - 2.5e-11 43.9 7.8 0.012 16.4 0.3 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Cwf_Cwc_15 PF04889.12 KKF92188.1 - 0.0017 18.1 8.5 0.0017 18.1 8.5 1.8 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 KKF92188.1 - 0.21 11.2 1.3 0.38 10.3 1.3 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 KKF92188.1 - 1.3 7.0 9.7 1.8 6.5 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KKF92188.1 - 2.2 7.6 10.1 3.7 6.8 10.1 1.3 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 KKF92188.1 - 6 6.7 9.0 10 6.0 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Retrotrans_gag PF03732.17 KKF92189.1 - 0.0011 19.1 1.0 0.0029 17.9 0.1 2.1 2 1 0 2 2 2 1 Retrotransposon gag protein EF-hand_4 PF12763.7 KKF92190.1 - 9e-27 93.1 0.0 6.7e-15 54.9 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KKF92190.1 - 0.0018 17.7 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KKF92190.1 - 0.0042 16.9 0.0 7.9 6.7 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain DUF1720 PF08226.11 KKF92190.1 - 0.0068 16.8 40.1 0.0068 16.8 40.1 7.9 4 2 3 7 7 7 4 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 KKF92190.1 - 0.0075 16.7 8.2 0.15 12.5 0.1 3.9 4 0 0 4 4 4 2 EF-hand domain pair CTP_transf_like PF01467.26 KKF92192.1 - 1.5e-05 25.2 0.0 3.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like Peptidase_S8 PF00082.22 KKF92193.1 - 3.4e-10 39.7 0.0 9.2e-09 35.0 0.0 2.2 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KKF92193.1 - 0.0042 17.8 0.0 0.0089 16.7 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain DUF1970 PF09301.10 KKF92194.1 - 0.056 13.7 0.0 22 5.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1970) DUF5395 PF17373.2 KKF92194.1 - 0.18 12.5 0.3 0.89 10.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5395) DUF3892 PF13031.6 KKF92194.1 - 0.35 11.5 1.7 27 5.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3892) PurK_C PF17769.1 KKF92195.1 - 0.046 13.4 0.0 21 4.9 0.0 4.0 5 0 0 5 5 5 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain RSN1_7TM PF02714.15 KKF92196.1 - 9.6e-77 258.0 27.4 1.4e-76 257.5 27.4 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KKF92196.1 - 1e-17 64.9 0.3 1e-17 64.9 0.3 2.2 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KKF92196.1 - 1.2e-14 54.2 0.0 3.6e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Sporozoite_P67 PF05642.11 KKF92196.1 - 0.07 11.2 10.2 0.11 10.5 10.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4225 PF13988.6 KKF92196.1 - 2.4 7.7 4.0 5.3 6.6 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) YhfT PF10797.9 KKF92197.1 - 0.021 13.9 0.2 0.033 13.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF5534 PF17686.1 KKF92197.1 - 0.19 12.0 0.5 0.34 11.1 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5534) Velvet PF11754.8 KKF92198.1 - 5.5e-41 141.2 0.9 3.8e-25 89.3 0.1 3.4 2 2 1 3 3 3 2 Velvet factor Hamartin PF04388.12 KKF92198.1 - 2.1 6.9 9.8 2.7 6.5 9.8 1.2 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 KKF92199.1 - 0.22 11.5 8.2 0.28 11.1 8.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase_fungal PF17667.1 KKF92200.1 - 2.2e-63 214.4 0.8 2.7e-63 214.1 0.8 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KKF92201.1 - 1.3e-119 399.7 0.0 1.5e-119 399.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KKF92201.1 - 0.00014 21.3 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain KCH PF16944.5 KKF92203.1 - 2.9e-95 318.8 7.0 3.4e-95 318.6 7.0 1.1 1 0 0 1 1 1 1 Fungal potassium channel RTP801_C PF07809.11 KKF92204.1 - 0.065 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 RTP801 C-terminal region NACHT_N PF17100.5 KKF92206.1 - 9.5e-62 208.7 0.2 9.5e-62 208.7 0.2 2.2 3 0 0 3 3 3 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 KKF92206.1 - 6.8e-25 86.9 6.6 2.2e-10 40.9 0.3 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.12 KKF92206.1 - 1.1e-17 64.4 0.1 4.5e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ANAPC4_WD40 PF12894.7 KKF92206.1 - 2.9e-09 37.1 0.2 0.0014 18.9 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_19 PF13245.6 KKF92206.1 - 0.0033 17.8 0.0 0.023 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Ge1_WD40 PF16529.5 KKF92206.1 - 0.014 14.4 2.7 0.29 10.0 0.1 2.8 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_22 PF13401.6 KKF92206.1 - 0.016 15.5 0.1 2.5 8.4 0.0 2.7 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 KKF92206.1 - 0.025 14.4 1.0 0.89 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKF92206.1 - 0.038 14.0 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Robl_LC7 PF03259.17 KKF92206.1 - 0.043 13.6 0.0 4 7.3 0.0 2.9 1 1 1 2 2 2 0 Roadblock/LC7 domain ResIII PF04851.15 KKF92206.1 - 0.049 13.6 0.1 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1664 PF07889.12 KKF92206.1 - 3.2 7.8 7.5 1.1 9.3 1.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF1539 PF07560.11 KKF92206.1 - 7 6.8 6.6 1.1 9.3 0.1 3.0 5 0 0 5 5 5 0 Domain of Unknown Function (DUF1539) MFS_1 PF07690.16 KKF92207.1 - 1.2e-37 129.7 19.6 1.5e-37 129.4 19.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKF92207.1 - 1.2e-09 37.6 6.6 1.2e-09 37.6 6.6 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KKF92207.1 - 2.5e-09 36.1 6.7 3.5e-09 35.7 6.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KKF92207.1 - 0.0004 19.8 5.3 0.00065 19.1 5.3 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KKF92207.1 - 0.26 10.1 9.2 0.09 11.6 4.4 2.2 2 1 0 2 2 2 0 MFS_1 like family DUF2178 PF09946.9 KKF92207.1 - 1.8 8.7 9.0 1.2 9.3 0.6 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) zf-C2H2 PF00096.26 KKF92208.1 - 1.3e-08 34.8 12.0 1.7e-05 25.0 1.8 3.7 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKF92208.1 - 4.2e-07 30.1 19.5 4.4e-07 30.0 1.8 3.3 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKF92208.1 - 4.8e-06 27.0 9.6 0.00042 20.9 1.4 3.8 4 0 0 4 4 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKF92208.1 - 4.9e-05 23.2 5.1 0.0054 16.7 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKF92208.1 - 0.01 16.1 0.2 0.01 16.1 0.2 3.9 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding Coilin_N PF15862.5 KKF92208.1 - 0.2 11.5 8.1 0.11 12.3 1.1 2.3 2 0 0 2 2 2 0 Coilin N-terminus Presenilin PF01080.17 KKF92208.1 - 0.22 10.3 13.5 0.29 9.8 13.5 1.1 1 0 0 1 1 1 0 Presenilin zf-C2HE PF16278.5 KKF92208.1 - 0.4 11.2 21.2 0.39 11.2 8.4 2.7 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger PAT1 PF09770.9 KKF92208.1 - 1.4 7.1 26.4 1.7 6.8 26.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 KKF92208.1 - 2.4 7.1 10.6 3.1 6.7 10.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 TMEM174 PF15029.6 KKF92208.1 - 3.6 7.2 7.1 0.8 9.4 1.5 2.1 2 0 0 2 2 2 0 Transmembrane protein 174 US2 PF02476.15 KKF92208.1 - 6.7 7.4 11.3 0.1 13.3 1.3 2.3 2 1 0 2 2 2 0 US2 family TMEM51 PF15345.6 KKF92208.1 - 7.4 6.3 15.5 11 5.8 15.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 zf-H2C2_5 PF13909.6 KKF92208.1 - 9.6 6.1 16.8 1.5 8.6 1.8 3.5 2 1 0 2 2 2 0 C2H2-type zinc-finger domain FlgI PF02119.16 KKF92209.1 - 0.039 12.9 0.0 0.66 8.8 0.0 2.0 2 0 0 2 2 2 0 Flagellar P-ring protein Usp PF00582.26 KKF92211.1 - 5.9e-22 78.7 2.1 7e-22 78.5 0.0 2.2 2 1 0 2 2 2 1 Universal stress protein family DUF1263 PF06882.12 KKF92211.1 - 0.012 15.6 0.7 0.074 13.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) Ribosomal_S7 PF00177.21 KKF92212.1 - 7.3e-25 87.4 0.0 1.3e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e dsrm PF00035.26 KKF92213.1 - 3.2e-06 27.7 0.0 4.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KKF92213.1 - 0.00026 21.2 0.1 0.00076 19.7 0.1 1.9 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Fungal_trans PF04082.18 KKF92214.1 - 5e-10 38.9 0.0 7.4e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KKF92215.1 - 1.9e-53 181.6 25.3 1.9e-53 181.6 25.3 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKF92215.1 - 8.4e-12 44.7 9.0 8.4e-12 44.7 9.0 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KKF92215.1 - 1.6e-08 33.4 3.9 2.8e-08 32.6 3.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KKF92215.1 - 0.002 16.6 7.3 0.002 16.6 7.3 2.5 3 0 0 3 3 3 1 Transmembrane secretion effector Phage_holin_2_4 PF16082.5 KKF92215.1 - 0.14 11.9 0.0 0.14 11.9 0.0 3.2 4 1 1 5 5 5 0 Bacteriophage holin family, superfamily II-like OATP PF03137.20 KKF92215.1 - 0.2 9.9 10.8 0.81 7.9 0.3 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Jacalin PF01419.17 KKF92216.1 - 0.00015 21.7 0.2 0.0019 18.1 0.0 2.6 3 0 0 3 3 3 1 Jacalin-like lectin domain RRM_1 PF00076.22 KKF92217.1 - 0.0025 17.6 0.1 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NUDIX PF00293.28 KKF92219.1 - 3.3e-24 85.4 0.0 5.8e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_1 PF00583.25 KKF92220.1 - 3.9e-09 36.8 0.0 7.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KKF92220.1 - 4e-08 33.4 0.1 1.4e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKF92220.1 - 2.4e-06 27.9 0.0 4.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKF92220.1 - 1.1e-05 25.4 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKF92220.1 - 0.00029 20.7 0.0 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KKF92220.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RPA_C PF08784.11 KKF92221.1 - 5.6e-12 46.2 0.2 1.1e-11 45.3 0.2 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KKF92221.1 - 0.0021 18.0 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4766 PF15973.5 KKF92221.1 - 0.022 15.3 13.8 0.39 11.3 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) Lon_C PF05362.13 KKF92222.1 - 4.7e-36 124.3 1.1 1.1e-19 70.8 0.2 2.6 2 1 1 3 3 2 2 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KKF92222.1 - 2.4e-27 96.2 0.0 3.8e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KKF92222.1 - 8.1e-23 81.3 0.0 2.1e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKF92222.1 - 1.7e-08 34.6 0.0 5.5e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKF92222.1 - 3.6e-07 30.7 0.1 1.9e-06 28.4 0.0 2.2 1 1 1 2 2 1 1 AAA ATPase domain AAA_2 PF07724.14 KKF92222.1 - 1.7e-05 25.0 0.0 6.9e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKF92222.1 - 6.4e-05 23.2 0.0 0.011 16.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 KKF92222.1 - 0.00021 21.1 0.0 0.00068 19.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKF92222.1 - 0.00022 21.0 0.0 0.00086 19.1 0.0 2.0 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain ChlI PF13541.6 KKF92222.1 - 0.001 18.9 0.2 0.019 14.8 0.1 2.4 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_33 PF13671.6 KKF92222.1 - 0.003 17.7 0.1 0.0087 16.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 KKF92222.1 - 0.0068 15.6 0.1 0.086 12.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.17 KKF92222.1 - 0.009 15.8 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KKF92222.1 - 0.019 15.0 0.0 0.062 13.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 KKF92222.1 - 0.019 14.2 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_23 PF13476.6 KKF92222.1 - 0.021 15.4 0.0 0.088 13.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 KKF92222.1 - 0.023 14.6 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KKF92222.1 - 0.037 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KKF92222.1 - 0.039 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KKF92222.1 - 0.047 13.1 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_17 PF13207.6 KKF92222.1 - 0.057 13.9 0.5 3 8.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 KKF92222.1 - 0.062 13.2 0.7 0.51 10.2 0.0 2.5 2 1 1 3 3 2 0 NTPase AAA_7 PF12775.7 KKF92222.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KKF92222.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KKF92222.1 - 0.077 12.4 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KKF92222.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 KKF92222.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KKF92222.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKF92222.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MDH PF02315.16 KKF92224.1 - 0.0077 16.3 0.3 0.009 16.1 0.3 1.1 1 0 0 1 1 1 1 Methanol dehydrogenase beta subunit GST_C_3 PF14497.6 KKF92226.1 - 7.7e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKF92226.1 - 1.4e-06 28.5 0.0 3.5e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKF92226.1 - 0.0002 21.7 0.0 0.00035 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKF92226.1 - 0.00072 19.5 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKF92226.1 - 0.00095 19.3 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKF92226.1 - 0.0015 18.8 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NUDIX PF00293.28 KKF92227.1 - 0.06 13.4 0.0 0.19 11.8 0.0 1.9 1 1 1 2 2 2 0 NUDIX domain Sel1 PF08238.12 KKF92229.1 - 1.4e-15 57.4 20.4 5e-06 27.0 0.1 7.1 7 0 0 7 7 7 4 Sel1 repeat UAA PF08449.11 KKF92230.1 - 5.9e-09 35.5 18.4 8e-09 35.1 18.4 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KKF92230.1 - 0.00023 21.3 30.3 0.00036 20.7 11.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family UPF0370 PF13980.6 KKF92230.1 - 0.035 14.1 0.0 0.12 12.4 0.0 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) MBOAT PF03062.19 KKF92231.1 - 2.4e-39 135.7 2.2 9.2e-28 97.6 0.3 2.4 1 1 1 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.21 KKF92231.1 - 0.095 12.5 2.1 0.21 11.3 2.1 1.5 1 0 0 1 1 1 0 PAP2 superfamily PI-PLC-X PF00388.19 KKF92232.1 - 1.1e-09 38.0 0.0 1.6e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Pterin_bind PF00809.22 KKF92233.1 - 1.3e-78 264.1 0.0 1.6e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KKF92233.1 - 3.5e-23 82.2 0.0 7.5e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF2922 PF11148.8 KKF92233.1 - 0.046 13.5 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) NMO PF03060.15 KKF92234.1 - 1.2e-54 185.9 0.0 1.7e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKF92234.1 - 1.3e-09 37.5 0.0 2e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKF92234.1 - 2.1e-06 27.0 1.1 3.1e-06 26.5 1.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Rho_GDI PF02115.17 KKF92234.1 - 0.085 12.6 1.2 0.12 12.1 1.2 1.2 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor ArfGap PF01412.18 KKF92235.1 - 3.1e-35 120.8 0.4 6.1e-35 119.8 0.4 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CAP_GLY PF01302.25 KKF92236.1 - 1e-21 76.7 1.7 1.5e-21 76.2 1.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KKF92236.1 - 7.3e-16 58.4 0.0 1.1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KKF92236.1 - 0.0016 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family PB1 PF00564.24 KKF92236.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 PB1 domain T6_Ig_like PF18002.1 KKF92236.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 T6 antigen Ig like domain Methyltransf_23 PF13489.6 KKF92237.1 - 0.0002 21.2 0.0 0.00075 19.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF92237.1 - 0.00043 20.9 0.0 0.0024 18.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF92237.1 - 0.0017 19.0 0.1 0.24 12.1 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF92237.1 - 0.011 16.5 0.0 0.019 15.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-binding PF00249.31 KKF92238.1 - 6.4e-11 42.3 0.8 2.3e-10 40.5 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKF92238.1 - 6.7e-05 23.1 0.2 0.00023 21.3 0.2 1.9 1 1 1 2 2 2 1 Myb-like DNA-binding domain WD40 PF00400.32 KKF92239.1 - 6.1e-103 333.9 47.9 5e-11 43.0 0.3 11.9 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92239.1 - 2.2e-44 149.7 12.1 0.00022 21.5 0.0 10.0 2 1 8 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain NACHT_N PF17100.5 KKF92239.1 - 1.3e-40 139.6 2.5 2.3e-35 122.5 0.2 2.9 2 1 1 3 3 3 2 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KKF92239.1 - 1.1e-18 67.7 0.0 2.6e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KKF92239.1 - 1.1e-14 54.2 23.0 0.0013 17.8 0.8 6.6 1 1 5 6 6 6 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Germane PF10646.9 KKF92239.1 - 8.5e-05 23.3 0.0 43 5.0 0.0 6.4 7 1 0 7 7 6 0 Sporulation and spore germination PD40 PF07676.12 KKF92239.1 - 0.00041 20.2 0.0 90 3.2 0.0 6.4 8 0 0 8 8 7 0 WD40-like Beta Propeller Repeat Big_7 PF17957.1 KKF92239.1 - 0.00079 20.1 19.2 6.8 7.5 0.1 8.1 5 2 2 7 7 7 1 Bacterial Ig domain Cytochrom_D1 PF02239.16 KKF92239.1 - 0.001 17.7 8.6 0.11 11.0 0.1 4.4 1 1 4 6 6 6 3 Cytochrome D1 heme domain WD40_like PF17005.5 KKF92239.1 - 0.003 16.9 8.1 18 4.5 0.0 6.5 4 2 4 9 9 9 0 WD40-like domain Glyco_hydro_59 PF02057.15 KKF92239.1 - 0.072 12.3 0.3 0.15 11.3 0.3 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 DUF1241 PF06840.11 KKF92239.1 - 0.17 11.5 0.9 1.1 8.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) DUF5114 PF17141.4 KKF92239.1 - 0.41 11.2 2.0 47 4.6 0.1 4.3 3 2 1 5 5 4 0 Domain of unknown function (DUF5114) DUF3492 PF11997.8 KKF92239.1 - 0.44 10.2 2.2 1.5 8.5 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3492) AAA_11 PF13086.6 KKF92239.1 - 1.1 9.0 3.8 1.4 8.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain BAT PF15915.5 KKF92239.1 - 1.9 8.3 4.5 46 3.8 1.0 3.5 3 1 0 3 3 3 0 GAF and HTH_10 associated domain EMG1 PF03587.14 KKF92240.1 - 1.7e-78 262.7 0.0 2e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Choline_sulf_C PF12411.8 KKF92241.1 - 0.0021 17.9 0.4 88 3.0 0.0 5.4 5 0 0 5 5 5 1 Choline sulfatase enzyme C terminal Rad4 PF03835.15 KKF92241.1 - 0.0046 16.6 1.8 18 5.0 0.1 4.1 1 1 3 4 4 4 3 Rad4 transglutaminase-like domain RVT_1 PF00078.27 KKF92242.1 - 3.6e-23 82.3 0.0 4.6e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KKF92243.1 - 0.023 14.4 0.0 0.053 13.2 0.0 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type MADF_DNA_bdg PF10545.9 KKF92243.1 - 1.5 9.2 7.6 21 5.5 0.2 3.5 2 2 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Striatin PF08232.12 KKF92244.1 - 3.1e-34 118.8 0.1 3.1e-34 118.8 0.1 3.3 2 1 1 3 3 3 1 Striatin family WD40 PF00400.32 KKF92244.1 - 3e-24 84.8 23.6 3.2e-05 24.6 0.4 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat TFIIA PF03153.13 KKF92244.1 - 6.4e-06 26.4 36.1 1e-05 25.7 36.1 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ANAPC4_WD40 PF12894.7 KKF92244.1 - 3.6e-05 24.0 1.6 0.19 12.0 0.0 4.9 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PAT1 PF09770.9 KKF92244.1 - 0.0096 14.2 28.7 0.012 14.0 28.7 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.13 KKF92244.1 - 1.1 8.2 22.2 2.2 7.2 22.2 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Exonuc_VII_L PF02601.15 KKF92244.1 - 4.8 6.7 19.0 3.7 7.0 15.2 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Lin-8 PF03353.15 KKF92244.1 - 5.3 6.5 27.1 10 5.6 27.1 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sugar_tr PF00083.24 KKF92245.1 - 1.1e-60 205.9 19.8 6e-47 160.5 4.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKF92245.1 - 2.6e-19 69.4 26.3 5.8e-19 68.2 26.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily HTH_29 PF13551.6 KKF92245.1 - 0.0042 17.1 1.4 0.011 15.7 0.2 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 KKF92245.1 - 0.0078 16.8 2.7 0.025 15.2 0.4 2.4 1 1 1 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KKF92245.1 - 0.025 14.7 0.0 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_20 PF12840.7 KKF92245.1 - 0.07 13.2 0.5 1.1 9.4 0.2 2.9 4 0 0 4 4 4 0 Helix-turn-helix domain Cas9_a PF18470.1 KKF92245.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain SET PF00856.28 KKF92246.1 - 3.6e-09 37.2 0.0 6.2e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 SET domain WD40 PF00400.32 KKF92248.1 - 2e-58 193.0 13.7 8.6e-11 42.2 0.2 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat NACHT_N PF17100.5 KKF92248.1 - 1.2e-34 120.1 2.0 1e-28 100.7 0.1 2.8 2 1 1 3 3 3 2 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 KKF92248.1 - 4.5e-24 84.6 4.9 0.0011 19.2 0.0 6.1 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KKF92248.1 - 2.8e-15 56.6 0.0 5.3e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KKF92248.1 - 7e-09 35.1 5.2 0.00011 21.3 0.4 4.3 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Robl_LC7 PF03259.17 KKF92248.1 - 4.6e-05 23.1 1.6 0.9 9.3 0.0 5.2 2 2 3 5 5 5 1 Roadblock/LC7 domain Cytochrom_D1 PF02239.16 KKF92248.1 - 0.00049 18.7 0.4 0.095 11.2 0.0 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain TsaE PF02367.17 KKF92248.1 - 0.0042 17.1 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PD40 PF07676.12 KKF92248.1 - 0.012 15.6 0.0 66 3.6 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Big_7 PF17957.1 KKF92248.1 - 1 10.2 10.3 7.1 7.5 0.2 4.6 2 1 2 4 4 4 0 Bacterial Ig domain DNA_Packaging PF11053.8 KKF92249.1 - 0.033 14.0 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Terminase DNA packaging enzyme DUF4307 PF14155.6 KKF92249.1 - 0.094 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) TGF_beta_GS PF08515.12 KKF92249.1 - 0.13 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif zf-CCHC PF00098.23 KKF92254.1 - 0.00046 20.1 2.7 0.00046 20.1 2.7 1.9 2 0 0 2 2 2 1 Zinc knuckle SCAN PF02023.17 KKF92254.1 - 0.0083 15.9 0.3 0.016 15.0 0.3 1.6 1 1 0 1 1 1 1 SCAN domain Peptidase_Mx1 PF15890.5 KKF92254.1 - 0.027 13.9 0.3 0.037 13.5 0.3 1.1 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase Retrotran_gag_2 PF14223.6 KKF92254.1 - 0.028 14.1 0.8 0.073 12.7 0.8 1.8 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 KKF92254.1 - 0.031 14.0 0.2 0.1 12.4 0.1 2.0 2 0 0 2 2 2 0 Zinc knuckle DAG_kinase_N PF14513.6 KKF92254.1 - 0.051 13.8 1.6 0.063 13.5 1.6 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus TMEM95 PF15203.6 KKF92254.1 - 0.053 13.2 1.0 0.093 12.4 1.0 1.4 1 0 0 1 1 1 0 TMEM95 family zf-CCHC_5 PF14787.6 KKF92254.1 - 0.97 9.2 9.1 0.35 10.6 4.9 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger IDO PF01231.18 KKF92256.1 - 3.5e-33 115.1 0.0 4.8e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Dak2 PF02734.17 KKF92257.1 - 0.003 17.5 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 DAK2 domain Bacteriocin_IIi PF11758.8 KKF92257.1 - 0.0051 16.6 0.3 0.35 10.7 0.0 2.3 2 0 0 2 2 2 1 Aureocin-like type II bacteriocin Methyltransf_28 PF02636.17 KKF92257.1 - 0.0077 15.9 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Nup_retrotrp_bd PF10599.9 KKF92257.1 - 0.011 16.3 5.6 0.28 11.9 0.3 2.7 2 0 0 2 2 2 0 Retro-transposon transporting motif eIF-5_eIF-2B PF01873.17 KKF92257.1 - 0.23 11.3 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 COG6 PF06419.11 KKF92257.1 - 0.31 9.2 0.2 18 3.4 0.0 2.4 3 0 0 3 3 3 0 Conserved oligomeric complex COG6 PAP2_3 PF14378.6 KKF92258.1 - 2.9e-35 121.7 10.9 3.2e-25 88.9 2.8 2.5 1 1 1 2 2 2 2 PAP2 superfamily Hce2 PF14856.6 KKF92258.1 - 0.0002 21.6 0.0 0.00034 20.8 0.0 1.4 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF2953 PF11167.8 KKF92258.1 - 0.023 14.8 0.2 0.5 10.5 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) PAP2 PF01569.21 KKF92258.1 - 2.6 7.8 14.2 0.027 14.2 2.9 2.9 3 1 0 3 3 3 0 PAP2 superfamily Complex1_LYR_2 PF13233.6 KKF92259.1 - 3.8e-19 69.2 0.5 5.7e-19 68.7 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KKF92259.1 - 1.4e-11 44.3 0.3 2.7e-11 43.3 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KKF92259.1 - 0.018 15.6 0.1 0.032 14.8 0.1 1.4 1 0 0 1 1 1 0 Complex1_LYR-like FMO-like PF00743.19 KKF92260.1 - 4.8e-10 38.5 0.0 1.7e-08 33.4 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KKF92260.1 - 2.8e-08 33.8 0.0 8.3e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKF92260.1 - 0.00067 19.7 0.0 0.2 11.7 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KKF92260.1 - 0.003 16.7 0.0 0.25 10.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KKF92260.1 - 0.015 14.5 0.0 0.12 11.6 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_16 PF10294.9 KKF92261.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 2 0 0 2 2 2 0 Lysine methyltransferase Mito_carr PF00153.27 KKF92262.1 - 2.9e-44 148.9 10.3 1.1e-18 66.9 0.2 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KKF92262.1 - 0.002 17.3 4.6 0.011 14.9 0.3 2.5 2 1 0 2 2 2 2 Gammaproteobacterial serine protease DUF3337 PF11816.8 KKF92263.1 - 3.2e-54 183.4 0.0 6.4e-54 182.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KKF92263.1 - 4e-19 68.6 8.8 0.00028 21.6 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KKF92263.1 - 6.2e-05 21.8 0.3 0.016 13.9 0.0 2.8 3 0 0 3 3 3 2 Nucleoporin Nup120/160 NeA_P2 PF12312.8 KKF92263.1 - 0.02 14.4 0.3 0.038 13.4 0.3 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein ANAPC4_WD40 PF12894.7 KKF92263.1 - 0.032 14.5 0.0 0.17 12.2 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain LSM PF01423.22 KKF92265.1 - 3.9e-19 68.1 0.1 4.5e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF3828 PF12883.7 KKF92265.1 - 0.069 13.5 0.0 0.072 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) DBR1 PF05011.13 KKF92266.1 - 1.4e-11 45.0 0.0 2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KKF92266.1 - 0.0018 18.8 0.1 0.0023 18.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Skp1_POZ PF03931.15 KKF92267.1 - 3.7e-07 30.2 0.0 5.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ras PF00071.22 KKF92268.1 - 2.4e-33 115.0 0.0 3.5e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF92268.1 - 7.2e-12 45.6 0.0 1.7e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF92268.1 - 0.17 11.3 0.0 0.37 10.2 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family FOXP-CC PF16159.5 KKF92269.1 - 0.029 15.0 1.4 0.069 13.8 1.4 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain Aquarius_N PF16399.5 KKF92269.1 - 0.032 12.3 0.0 0.04 12.0 0.0 1.0 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus FANCL_C PF11793.8 KKF92269.1 - 0.13 12.4 1.1 0.25 11.5 1.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain DUF393 PF04134.12 KKF92269.1 - 0.16 13.3 0.0 0.38 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF393 Hexapep PF00132.24 KKF92270.1 - 6.7e-06 25.6 1.6 0.065 13.0 0.1 3.2 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KKF92270.1 - 1.7e-05 25.2 0.0 2.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KKF92270.1 - 0.0007 18.7 1.8 0.003 16.6 1.8 1.8 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KKF92270.1 - 0.0018 16.5 0.2 0.003 15.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 KKF92270.1 - 0.0036 16.9 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KKF92270.1 - 0.1 12.4 5.3 8.6 6.2 0.6 3.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase RVT_2 PF07727.14 KKF92272.1 - 4.3e-05 23.3 0.0 7.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KKF92272.1 - 0.00011 21.9 0.1 0.00029 20.5 0.1 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KKF92272.1 - 0.0011 18.9 6.0 0.0019 18.2 6.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Hep_59 PF07052.11 KKF92272.1 - 9.9 7.0 7.2 0.98 10.2 0.6 2.7 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 Clathrin PF00637.20 KKF92273.1 - 5.4e-199 652.1 27.5 4.4e-32 110.9 2.4 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KKF92273.1 - 6.6e-32 109.2 0.3 3.3e-31 107.0 0.2 2.4 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 KKF92273.1 - 1.3e-31 107.3 2.1 5.1e-06 26.5 0.0 6.8 6 0 0 6 6 6 6 Clathrin propeller repeat Evr1_Alr PF04777.13 KKF92273.1 - 4.4e-24 84.9 0.0 1.1e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 Erv1 / Alr family TPR_14 PF13428.6 KKF92273.1 - 7.3e-05 23.3 2.1 2.4 9.2 0.0 7.4 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKF92273.1 - 0.00065 19.5 5.3 6.2 7.1 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat PQQ_2 PF13360.6 KKF92273.1 - 0.021 14.4 0.1 4.7 6.7 0.1 2.5 2 0 0 2 2 2 0 PQQ-like domain 6PF2K PF01591.18 KKF92273.1 - 0.17 11.2 1.6 0.28 10.5 0.2 2.1 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Vps39_1 PF10366.9 KKF92273.1 - 0.57 10.5 4.3 15 5.9 0.0 4.8 5 1 0 5 5 5 0 Vacuolar sorting protein 39 domain 1 TPR_8 PF13181.6 KKF92273.1 - 0.62 10.4 9.7 1.8 9.0 0.1 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat Clathrin-link PF09268.10 KKF92273.1 - 0.69 9.3 2.8 0.47 9.9 0.3 2.1 2 0 0 2 2 2 0 Clathrin, heavy-chain linker Proteasome PF00227.26 KKF92274.1 - 5.1e-47 159.8 0.2 5.9e-47 159.6 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Diphthami_syn_2 PF01902.17 KKF92275.1 - 9.8e-23 80.8 0.0 3.4e-18 66.0 0.0 3.3 2 1 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KKF92275.1 - 1.3e-12 47.7 0.1 4.7e-08 33.1 0.0 3.6 3 1 0 3 3 3 2 Endoribonuclease L-PSP Exo_endo_phos_2 PF14529.6 KKF92276.1 - 3.5e-16 59.1 2.0 4.8e-16 58.7 0.2 2.2 2 1 1 3 3 3 1 Endonuclease-reverse transcriptase DUF1966 PF09260.11 KKF92276.1 - 0.06 13.6 3.7 6.3 7.1 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1966) Exo_endo_phos PF03372.23 KKF92276.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Ribosomal_L31e PF01198.19 KKF92276.1 - 9.4 6.6 6.4 23 5.3 0.4 3.1 3 0 0 3 3 3 0 Ribosomal protein L31e WD40 PF00400.32 KKF92278.1 - 1.9e-140 452.6 47.9 8.5e-11 42.2 0.5 14.5 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92278.1 - 3.7e-59 197.0 16.6 0.00056 20.2 0.0 14.1 1 1 13 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KKF92278.1 - 4.5e-20 72.2 0.0 7.4e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KKF92278.1 - 2.2e-15 56.1 0.0 11 6.1 0.0 12.6 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KKF92278.1 - 3.4e-15 55.8 26.4 0.063 12.2 0.3 11.2 1 1 7 9 9 9 7 WD40 region of Ge1, enhancer of mRNA-decapping protein Robl_LC7 PF03259.17 KKF92278.1 - 2.5e-13 49.6 10.2 2.1 8.2 0.0 11.4 3 2 8 11 11 11 1 Roadblock/LC7 domain Cytochrom_D1 PF02239.16 KKF92278.1 - 6.7e-06 24.9 17.7 0.24 9.9 0.5 6.8 1 1 10 11 11 11 4 Cytochrome D1 heme domain Fibrinogen_aC PF12160.8 KKF92278.1 - 2.9e-05 23.8 4.5 46 4.0 0.0 9.1 12 0 0 12 12 11 0 Fibrinogen alpha C domain Asp_decarbox PF02261.16 KKF92278.1 - 0.00016 21.6 0.0 33 4.5 0.0 6.6 3 3 6 10 10 8 0 Aspartate decarboxylase AAA_16 PF13191.6 KKF92278.1 - 0.0014 19.1 0.0 0.0044 17.4 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_19 PF13245.6 KKF92278.1 - 0.0016 18.8 0.0 0.0048 17.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain Roc PF08477.13 KKF92278.1 - 0.0026 18.0 9.7 19 5.5 0.0 6.8 4 2 2 8 8 7 0 Ras of Complex, Roc, domain of DAPkinase Big_7 PF17957.1 KKF92278.1 - 0.0051 17.5 45.7 33 5.3 0.3 12.3 4 3 8 12 12 12 0 Bacterial Ig domain Patatin PF01734.22 KKF92278.1 - 0.014 15.6 0.6 0.16 12.1 0.0 2.5 1 1 1 2 2 2 0 Patatin-like phospholipase AAA_11 PF13086.6 KKF92278.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KKF92278.1 - 0.044 13.9 0.2 0.63 10.1 0.1 2.4 1 1 0 1 1 1 0 Helicase HerA, central domain PUA_3 PF17785.1 KKF92278.1 - 0.055 13.3 11.2 89 3.0 0.0 7.8 11 0 0 11 11 9 0 PUA-like domain POLO_box PF00659.18 KKF92278.1 - 0.072 13.3 2.2 1.8 8.8 0.0 4.7 6 2 0 6 6 2 0 POLO box duplicated region TsaE PF02367.17 KKF92278.1 - 0.091 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KKF92278.1 - 0.1 12.5 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Toxin_32 PF08120.11 KKF92278.1 - 0.1 12.4 0.0 5e+02 0.6 0.0 5.6 7 0 0 7 7 6 0 Tamulustoxin family AAA_22 PF13401.6 KKF92278.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4329 PF14220.6 KKF92278.1 - 0.12 12.3 0.7 49 4.0 0.0 4.2 3 1 2 5 5 4 0 Domain of unknown function (DUF4329) RPN6_C_helix PF18503.1 KKF92278.1 - 0.13 12.0 0.0 4.8 7.0 0.0 2.8 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain NACHT PF05729.12 KKF92279.1 - 8.6e-22 77.8 0.0 1.3e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KKF92279.1 - 0.00092 19.6 0.0 0.0045 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKF92279.1 - 0.0045 17.3 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKF92279.1 - 0.01 16.2 0.0 0.058 13.8 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 KKF92279.1 - 0.019 14.8 0.0 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKF92279.1 - 0.028 14.4 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 KKF92279.1 - 0.035 13.3 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RasGEF_N_2 PF14663.6 KKF92279.1 - 0.039 14.3 0.5 0.16 12.4 0.1 2.3 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RNA_helicase PF00910.22 KKF92279.1 - 0.11 13.0 0.3 0.38 11.2 0.0 2.2 2 2 0 2 2 2 0 RNA helicase Borrelia_P83 PF05262.11 KKF92281.1 - 0.0023 16.5 17.0 0.0027 16.3 17.0 1.0 1 0 0 1 1 1 1 Borrelia P83/100 protein NPR3 PF03666.13 KKF92281.1 - 2.2 7.0 8.1 3 6.6 8.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC27 PF09507.10 KKF92281.1 - 2.4 7.4 21.8 2.9 7.2 21.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_11 PF13086.6 KKF92281.1 - 7.9 6.2 11.6 12 5.5 11.6 1.3 1 0 0 1 1 1 0 AAA domain Asp-B-Hydro_N PF05279.11 KKF92281.1 - 9.5 6.2 18.7 16 5.4 18.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AAA_13 PF13166.6 KKF92281.1 - 9.5 4.7 11.6 11 4.6 11.6 1.1 1 0 0 1 1 1 0 AAA domain Glyco_hydro_18 PF00704.28 KKF92282.1 - 4.6e-23 82.4 0.1 2.2e-22 80.2 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 TPP_enzyme_N PF02776.18 KKF92283.1 - 8.3e-57 191.5 0.1 7e-56 188.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KKF92283.1 - 7.1e-49 165.5 0.1 1.8e-47 161.0 0.1 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKF92283.1 - 8.4e-39 132.4 0.2 1.7e-38 131.5 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain SGTA_dimer PF16546.5 KKF92284.1 - 3.2e-24 84.5 0.1 6.2e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KKF92284.1 - 1.8e-13 49.7 6.8 4.4e-06 26.3 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKF92284.1 - 3.8e-12 45.3 10.8 6.2e-05 22.8 0.2 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKF92284.1 - 3.6e-08 33.0 4.9 4.4e-05 23.1 1.7 3.1 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 KKF92284.1 - 7.9e-06 25.7 9.8 0.31 11.4 0.4 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat STI1 PF17830.1 KKF92284.1 - 1.1e-05 25.2 4.7 0.0028 17.6 4.0 2.5 2 0 0 2 2 2 1 STI1 domain TPR_19 PF14559.6 KKF92284.1 - 2e-05 25.0 4.7 0.039 14.5 0.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKF92284.1 - 2.7e-05 24.7 7.3 2.7e-05 24.7 7.3 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKF92284.1 - 0.00036 20.7 4.2 0.011 16.1 0.6 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKF92284.1 - 0.00049 20.3 4.3 0.00049 20.3 4.3 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKF92284.1 - 0.00094 19.3 2.3 0.014 15.5 0.5 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKF92284.1 - 0.0032 18.2 17.8 0.079 13.8 0.1 4.8 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KKF92284.1 - 0.014 16.0 5.6 1.7 9.4 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKF92284.1 - 0.016 15.2 2.6 0.88 9.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KKF92284.1 - 0.02 15.3 4.0 0.99 9.8 0.8 2.5 1 1 1 2 2 2 0 Bacterial transcriptional activator domain XPC-binding PF09280.11 KKF92284.1 - 0.059 13.1 1.2 0.1 12.3 0.7 1.6 2 0 0 2 2 1 0 XPC-binding domain MIT PF04212.18 KKF92284.1 - 1.7 8.7 6.9 0.83 9.8 0.5 2.9 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain ABC_tran PF00005.27 KKF92285.1 - 2.9e-32 112.0 0.0 6e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KKF92285.1 - 2.4e-21 76.6 2.5 3.5e-21 76.1 2.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KKF92285.1 - 6.6e-06 25.7 1.6 2.4e-05 23.9 0.3 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKF92285.1 - 0.0038 17.2 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KKF92285.1 - 0.0064 16.9 0.1 0.42 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KKF92285.1 - 0.074 12.8 0.1 0.3 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KKF92285.1 - 0.075 12.5 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 KKF92285.1 - 0.081 12.7 0.3 0.24 11.2 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KKF92285.1 - 0.081 12.9 0.0 8.6 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 KKF92285.1 - 0.095 12.5 0.2 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KKF92285.1 - 0.15 12.3 0.2 1 9.6 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KKF92285.1 - 0.33 11.4 1.3 3.6 8.0 1.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_16 PF00722.21 KKF92286.1 - 4.9e-45 153.2 1.4 8.4e-45 152.4 1.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I PF01028.20 KKF92287.1 - 1.7e-96 322.0 5.1 1.7e-96 322.0 5.1 2.4 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KKF92287.1 - 9.1e-96 319.4 4.5 9.1e-96 319.4 4.5 2.8 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KKF92287.1 - 1.2e-29 102.0 0.2 5e-29 100.0 0.2 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4336 PF14234.6 KKF92288.1 - 2.4e-14 53.3 0.0 5.4e-09 35.7 0.0 3.4 2 1 0 3 3 3 2 Domain of unknown function (DUF4336) PI-PLC-X PF00388.19 KKF92288.1 - 4e-06 26.5 0.0 9.9e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Alk_phosphatase PF00245.20 KKF92289.1 - 6.2e-69 232.9 0.4 1.9e-68 231.4 0.4 1.7 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 KKF92289.1 - 7.6e-10 38.9 0.9 1.3e-09 38.1 0.9 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KKF92289.1 - 5.5e-05 22.6 0.3 0.00094 18.6 0.0 2.2 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 KKF92289.1 - 6.8e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KKF92289.1 - 0.0015 17.2 0.2 0.0022 16.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) PglZ PF08665.12 KKF92289.1 - 0.038 14.1 0.2 0.083 13.0 0.2 1.5 1 0 0 1 1 1 0 PglZ domain Acyl-CoA_dh_N PF02771.16 KKF92290.1 - 0.17 12.5 0.3 0.46 11.2 0.1 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain KilA-N PF04383.13 KKF92291.1 - 2.4e-05 24.2 0.0 0.00089 19.1 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain BRCT_2 PF16589.5 KKF92292.1 - 1.4e-05 25.4 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KKF92292.1 - 0.0018 18.6 0.0 0.0047 17.3 0.0 1.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KKF92292.1 - 0.0026 17.7 0.1 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 KKF92292.1 - 0.022 15.0 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain DUF5436 PF17504.2 KKF92293.1 - 0.088 13.1 0.4 0.14 12.5 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5436) Glyco_hydro_4 PF02056.16 KKF92293.1 - 0.1 12.2 0.3 0.13 11.8 0.3 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase WD40 PF00400.32 KKF92294.1 - 4.3e-30 103.3 10.3 1.6e-08 35.0 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92294.1 - 4e-09 36.7 0.5 0.088 13.1 0.0 3.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF92294.1 - 1.3e-08 34.2 0.1 0.34 9.8 0.0 4.2 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KKF92294.1 - 3.9e-06 26.0 1.0 1.6e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KKF92294.1 - 5.4e-05 21.7 0.0 9.9e-05 20.8 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KKF92294.1 - 0.00034 19.4 2.5 0.053 12.2 0.1 3.6 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Hira PF07569.11 KKF92294.1 - 0.36 10.5 2.0 11 5.6 0.1 3.1 2 1 1 3 3 3 0 TUP1-like enhancer of split Pkinase PF00069.25 KKF92295.1 - 7.3e-10 38.7 0.0 1.7e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92295.1 - 8.8e-08 31.7 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 KKF92295.1 - 4.7e-07 30.0 0.0 1e-05 25.7 0.0 2.2 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKF92295.1 - 1e-06 28.5 0.2 0.13 12.6 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KKF92295.1 - 0.011 16.2 0.2 0.69 10.3 0.0 3.0 2 1 0 3 3 3 0 HEAT repeats Kinase-like PF14531.6 KKF92295.1 - 0.096 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF4105 PF13387.6 KKF92296.1 - 0.056 13.1 0.2 0.56 9.8 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4105) Dioxygenase_C PF00775.21 KKF92297.1 - 8.5e-11 41.6 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase DUF3430 PF11912.8 KKF92298.1 - 0.11 12.5 7.7 0.13 12.3 2.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3430) Sugar_tr PF00083.24 KKF92299.1 - 6e-137 457.2 18.7 6.9e-137 457.0 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF92299.1 - 7.3e-22 77.8 37.6 2e-21 76.3 28.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 KKF92300.1 - 3.6e-20 72.0 0.0 6.7e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KKF92300.1 - 1.3e-07 31.3 0.0 2.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KKF92300.1 - 0.0068 16.5 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AP_endonuc_2 PF01261.24 KKF92301.1 - 3.3e-32 111.6 0.2 5.4e-32 110.9 0.0 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DHquinase_II PF01220.19 KKF92302.1 - 1e-64 216.3 0.3 1.2e-64 216.2 0.3 1.0 1 0 0 1 1 1 1 Dehydroquinase class II adh_short PF00106.25 KKF92302.1 - 0.019 14.5 0.1 0.019 14.5 0.1 1.5 2 0 0 2 2 2 0 short chain dehydrogenase SSP160 PF06933.11 KKF92303.1 - 0.01 14.1 25.7 0.011 14.0 25.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pex14_N PF04695.13 KKF92303.1 - 0.16 12.6 6.6 0.19 12.4 6.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MGC-24 PF05283.11 KKF92303.1 - 0.39 11.2 13.8 0.49 10.8 13.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Med3 PF11593.8 KKF92303.1 - 0.42 9.8 18.0 0.46 9.6 18.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FSA_C PF10479.9 KKF92303.1 - 0.72 7.9 14.0 0.74 7.9 14.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NST1 PF13945.6 KKF92303.1 - 0.79 9.8 6.8 0.91 9.6 6.8 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator SprA-related PF12118.8 KKF92303.1 - 0.8 8.8 14.6 0.81 8.8 14.6 1.1 1 0 0 1 1 1 0 SprA-related family SOG2 PF10428.9 KKF92303.1 - 1.2 8.2 18.3 1.4 8.1 18.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Menin PF05053.13 KKF92303.1 - 1.6 7.0 7.2 1.7 6.9 7.2 1.0 1 0 0 1 1 1 0 Menin BPS1 PF05633.11 KKF92303.1 - 2.8 6.8 7.6 3 6.7 7.6 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related Shisa PF13908.6 KKF92303.1 - 3.3 7.9 8.7 4 7.6 8.7 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 KKF92303.1 - 3.6 8.6 4.4 5.2 8.1 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF5383 PF17355.2 KKF92303.1 - 4.4 7.7 4.8 5.6 7.4 4.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Sporozoite_P67 PF05642.11 KKF92303.1 - 7.9 4.4 17.1 9.1 4.2 17.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF515 PF04415.12 KKF92303.1 - 8.2 4.7 21.6 9 4.6 21.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Apt1 PF10351.9 KKF92303.1 - 9.7 4.9 13.5 9.7 4.9 13.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Inositol_P PF00459.25 KKF92304.1 - 5.8e-77 258.9 0.0 6.6e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Fungal_trans PF04082.18 KKF92305.1 - 1.4e-18 66.9 0.1 2.1e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF92305.1 - 3.7e-07 30.2 9.4 6.5e-07 29.4 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3535 PF12054.8 KKF92305.1 - 0.024 13.9 2.4 0.04 13.2 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) FliD_N PF02465.18 KKF92305.1 - 2.6 8.8 6.5 0.39 11.4 1.0 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DHquinase_I PF01487.15 KKF92306.1 - 3.3e-21 76.6 0.0 5.7e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KKF92306.1 - 2.8e-20 72.4 0.0 8.5e-20 70.8 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KKF92306.1 - 3.4e-09 36.3 0.0 7.1e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain SKI PF01202.22 KKF92306.1 - 3.3e-08 33.8 0.1 6.1e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.20 KKF92306.1 - 4.2e-07 30.1 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KKF92306.1 - 0.026 14.8 0.1 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KKF92306.1 - 0.068 13.7 0.2 0.27 11.8 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AAA_16 PF13191.6 KKF92306.1 - 0.36 11.2 1.5 1.5 9.2 0.1 2.5 3 1 0 3 3 3 0 AAA ATPase domain TauD PF02668.16 KKF92307.1 - 2.3e-32 112.9 0.1 2.9e-32 112.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Hydantoinase_B PF02538.14 KKF92308.1 - 7.6e-195 648.2 2.2 4.3e-161 536.8 1.3 2.2 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KKF92308.1 - 3.4e-99 331.8 0.6 8.5e-99 330.5 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KKF92308.1 - 2.5e-56 190.2 0.0 1.6e-54 184.3 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF5076 PF16826.5 KKF92308.1 - 0.0078 16.1 0.3 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5076) Trehalase PF01204.18 KKF92309.1 - 1.9e-112 376.7 0.0 2e-111 373.3 0.0 2.0 1 1 0 1 1 1 1 Trehalase EDR1 PF14381.6 KKF92309.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Retrotran_gag_2 PF14223.6 KKF92310.1 - 0.025 14.2 0.2 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF3268 PF11672.8 KKF92310.1 - 0.029 14.7 5.2 0.33 11.3 0.1 3.7 3 1 1 4 4 4 0 zinc-finger-containing domain U79_P34 PF03064.16 KKF92310.1 - 0.26 10.6 3.5 0.41 10.0 3.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Spore_III_AF PF09581.10 KKF92310.1 - 4.4 7.3 7.9 13 5.7 0.5 2.2 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) KxDL PF10241.9 KKF92310.1 - 9.8 6.5 7.1 25 5.2 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein rve PF00665.26 KKF92311.1 - 8.3e-22 77.6 0.3 4.5e-13 49.4 0.1 2.7 2 0 0 2 2 2 2 Integrase core domain gag_pre-integrs PF13976.6 KKF92311.1 - 1.6e-06 27.9 0.1 1.6e-06 27.9 0.1 2.1 3 0 0 3 3 3 1 GAG-pre-integrase domain MFS_1 PF07690.16 KKF92312.1 - 1.2e-47 162.5 50.9 1.9e-46 158.6 52.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKF92312.1 - 6.2e-22 77.7 24.6 1.1e-21 76.9 24.6 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKF92312.1 - 3e-09 36.3 13.6 3e-09 36.3 13.6 3.4 3 1 1 4 4 4 2 Sugar (and other) transporter Mur_ligase_M PF08245.12 KKF92313.1 - 6.5e-05 23.0 0.0 0.00043 20.3 0.0 2.3 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KKF92313.1 - 0.01 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 KKF92314.1 - 1.1e-05 25.5 0.1 7.6e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mitofilin PF09731.9 KKF92315.1 - 2.6e-133 446.1 40.1 1.6e-118 397.3 22.7 3.0 2 1 0 3 3 3 2 Mitochondrial inner membrane protein Pex14_N PF04695.13 KKF92315.1 - 0.081 13.6 16.6 0.17 12.5 6.7 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4363 PF14276.6 KKF92315.1 - 0.11 12.6 1.7 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) FAM76 PF16046.5 KKF92315.1 - 6.3 6.1 7.4 9.8 5.4 7.4 1.3 1 0 0 1 1 1 0 FAM76 protein Ras PF00071.22 KKF92316.1 - 3.1e-49 166.7 0.3 3.9e-49 166.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF92316.1 - 2.5e-27 95.5 0.3 4.2e-27 94.8 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF92316.1 - 3.9e-11 42.7 0.1 4.7e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKF92316.1 - 2.6e-06 27.1 0.0 3.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKF92316.1 - 0.00092 18.6 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKF92316.1 - 0.07 13.0 0.1 0.19 11.6 0.0 1.6 1 1 1 2 2 2 0 RsgA GTPase Syja_N PF02383.18 KKF92317.1 - 1.6e-91 307.0 0.0 2.2e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain NUDIX PF00293.28 KKF92317.1 - 4.9e-10 39.6 0.2 1.1e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 NUDIX domain GCHY-1 PF02649.14 KKF92317.1 - 0.088 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 Glyco_hydro_32N PF00251.20 KKF92319.1 - 3.6e-41 141.7 1.0 5.7e-41 141.1 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KKF92319.1 - 2.8e-25 89.1 0.0 4.5e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 KKF92319.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) Glyco_hydro_32N PF00251.20 KKF92320.1 - 5.3e-40 137.9 1.6 8.7e-40 137.2 1.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KKF92320.1 - 1.8e-25 89.8 0.0 2.8e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 KKF92320.1 - 0.09 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) L51_S25_CI-B8 PF05047.16 KKF92321.1 - 3.3e-11 42.9 0.0 4.1e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1687 PF07955.11 KKF92322.1 - 1.1e-25 90.6 0.1 2e-25 89.7 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) RNaseH_like PF04308.12 KKF92322.1 - 0.0035 17.3 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H-like ArsC PF03960.15 KKF92322.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 ArsC family Ribosomal_L14e PF01929.17 KKF92323.1 - 3.9e-27 94.6 3.9 5.3e-27 94.1 3.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KKF92323.1 - 0.0048 16.8 1.0 0.0083 16.0 0.0 1.8 2 0 0 2 2 2 1 KOW motif NAC PF01849.18 KKF92324.1 - 7.6e-23 80.3 0.2 3.4e-22 78.2 0.1 2.0 2 0 0 2 2 2 1 NAC domain RNA_pol_Rpo13 PF12136.8 KKF92324.1 - 0.042 13.8 10.9 0.11 12.4 10.9 1.7 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain Cytomega_UL84 PF06284.11 KKF92324.1 - 0.17 10.3 2.6 0.18 10.2 2.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SelP_N PF04592.14 KKF92324.1 - 0.19 11.1 6.5 0.36 10.2 6.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDC45 PF02724.14 KKF92324.1 - 1.7 6.8 12.9 0.051 11.9 6.5 1.6 2 0 0 2 2 2 0 CDC45-like protein PGA2 PF07543.12 KKF92324.1 - 2.6 8.0 13.3 3.3 7.7 0.3 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF4746 PF15928.5 KKF92324.1 - 5 6.5 18.9 9 5.6 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4746) EBV-NA3 PF05009.12 KKF92324.1 - 7.6 6.0 10.1 4.7 6.7 3.7 2.2 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Mt_ATP-synt_D PF05873.12 KKF92325.1 - 2.3e-22 79.5 2.4 2.7e-22 79.3 2.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Ferritin_2 PF13668.6 KKF92325.1 - 0.0091 16.2 0.4 0.011 15.9 0.4 1.2 1 0 0 1 1 1 1 Ferritin-like domain Med18 PF09637.10 KKF92325.1 - 0.043 13.6 0.3 0.054 13.3 0.3 1.1 1 0 0 1 1 1 0 Med18 protein Meth_synt_1 PF08267.12 KKF92325.1 - 0.052 13.1 0.2 0.2 11.2 0.0 1.7 1 1 1 2 2 2 0 Cobalamin-independent synthase, N-terminal domain GIDA_assoc PF13932.6 KKF92325.1 - 0.059 13.6 1.2 0.075 13.2 1.2 1.1 1 0 0 1 1 1 0 GidA associated domain CheZ PF04344.13 KKF92325.1 - 0.08 12.8 1.2 0.1 12.5 1.2 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Abhydrolase_3 PF07859.13 KKF92326.1 - 1.4e-25 90.4 0.1 2.3e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKF92326.1 - 0.0012 19.5 3.3 0.0019 18.8 3.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KKF92326.1 - 0.032 14.1 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) COesterase PF00135.28 KKF92326.1 - 0.16 10.8 0.3 0.52 9.1 0.3 1.7 1 1 0 1 1 1 0 Carboxylesterase family MPC PF03650.13 KKF92327.1 - 9.4e-47 157.7 1.6 9.4e-47 157.7 1.6 1.4 2 0 0 2 2 2 1 Mitochondrial pyruvate carriers DUF1657 PF07870.11 KKF92327.1 - 0.1 12.5 1.2 0.17 11.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) 4_1_CTD PF05902.13 KKF92328.1 - 0.13 12.4 0.5 0.25 11.4 0.2 1.7 1 1 0 1 1 1 0 4.1 protein C-terminal domain (CTD) DUF2064 PF09837.9 KKF92329.1 - 0.13 12.1 0.0 0.47 10.3 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) His_Phos_2 PF00328.22 KKF92332.1 - 4.2e-09 36.2 0.3 1.8e-07 30.9 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF3188 PF11384.8 KKF92332.1 - 0.05 13.3 0.1 16 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Mur_ligase_C PF02875.21 KKF92333.1 - 1.3e-05 25.4 0.1 0.00026 21.2 0.0 2.7 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain MEDS PF14417.6 KKF92333.1 - 0.054 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Pkinase PF00069.25 KKF92334.1 - 2.5e-72 243.4 0.0 6.1e-72 242.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92334.1 - 1.6e-49 168.5 0.0 2.7e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKF92334.1 - 1.3e-05 24.2 0.0 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KKF92334.1 - 0.012 14.9 0.0 0.055 12.8 0.0 1.9 2 0 0 2 2 2 0 Kinase-like DUF913 PF06025.12 KKF92334.1 - 0.052 12.5 0.0 0.61 9.0 0.0 2.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF913) Exo70 PF03081.15 KKF92334.1 - 0.089 11.8 0.4 0.24 10.4 0.4 1.7 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Glyco_hydro_3_C PF01915.22 KKF92335.1 - 1.2e-40 139.7 0.0 1.9e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KKF92335.1 - 3.7e-23 81.4 0.1 6.6e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 KKF92335.1 - 1.9e-21 76.8 0.0 2.8e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PhyH PF05721.13 KKF92336.1 - 1.1e-56 192.5 0.0 1.4e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2373 PF10180.9 KKF92337.1 - 1.8e-21 75.7 0.2 3e-21 75.0 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) RGCC PF15151.6 KKF92337.1 - 0.048 13.9 1.3 0.048 13.9 1.3 2.5 2 0 0 2 2 2 0 Response gene to complement 32 protein family Proteasome PF00227.26 KKF92338.1 - 1.2e-47 161.9 0.1 1.6e-47 161.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKF92338.1 - 2.8e-12 46.0 0.1 5e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature YnfE PF17452.2 KKF92338.1 - 0.078 13.3 0.1 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized YnfE-like Alk_phosphatase PF00245.20 KKF92338.1 - 0.15 10.9 0.1 0.27 10.2 0.1 1.4 1 0 0 1 1 1 0 Alkaline phosphatase Pkinase PF00069.25 KKF92340.1 - 5.7e-58 196.4 0.0 7.8e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92340.1 - 2.1e-20 73.1 0.0 3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF92340.1 - 6.1e-07 29.0 0.0 9.8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KKF92340.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKF92340.1 - 0.011 15.4 0.1 0.043 13.4 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 KKF92340.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain YfdX PF10938.8 KKF92341.1 - 0.086 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 YfdX protein Efg1 PF10153.9 KKF92342.1 - 1.4e-28 99.5 7.9 1.4e-28 99.5 7.9 2.1 2 0 0 2 2 2 1 rRNA-processing protein Efg1 dsrm PF00035.26 KKF92343.1 - 0.011 16.4 0.2 0.084 13.6 0.0 2.3 2 0 0 2 2 2 0 Double-stranded RNA binding motif Apt1 PF10351.9 KKF92343.1 - 0.039 12.8 0.3 0.047 12.6 0.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FTH PF01827.27 KKF92343.1 - 0.079 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 FTH domain PTS_2-RNA PF01885.16 KKF92344.1 - 1e-51 175.6 0.0 1.3e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family AAA PF00004.29 KKF92345.1 - 4.7e-15 56.2 0.0 1.5e-14 54.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KKF92345.1 - 5.1e-12 45.8 0.2 1.3e-11 44.5 0.2 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 KKF92345.1 - 3.4e-11 43.8 0.0 1.2e-10 42.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKF92345.1 - 8.9e-08 32.5 0.0 4.8e-07 30.1 0.0 2.2 3 0 0 3 3 3 1 AAA domain BAH PF01426.18 KKF92345.1 - 9.9e-07 28.6 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 KKF92345.1 - 0.0011 19.3 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KKF92345.1 - 0.0013 18.7 0.0 0.011 15.7 0.0 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KKF92345.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKF92345.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KKF92345.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKF92345.1 - 0.057 14.0 0.0 0.16 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKF92345.1 - 0.074 13.5 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Pheromone PF08015.11 KKF92345.1 - 0.1 13.7 2.0 0.38 11.8 2.0 2.0 1 0 0 1 1 1 0 Fungal mating-type pheromone ssDBP PF17878.1 KKF92345.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Single-stranded DNA-binding protein UvrD-helicase PF00580.21 KKF92345.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KKF92345.1 - 0.23 10.7 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.32 KKF92346.1 - 2e-45 151.8 14.5 1.5e-09 38.3 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92346.1 - 9.8e-06 25.8 0.4 3.9 7.8 0.1 4.6 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKF92346.1 - 0.035 12.7 3.2 11 4.5 0.0 3.8 2 2 1 4 4 4 0 Nucleoporin Nup120/160 Exo_endo_phos_2 PF14529.6 KKF92347.1 - 2.2e-10 40.4 0.1 3.9e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KKF92347.1 - 1.2e-05 25.0 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KKF92347.1 - 0.006 16.8 0.9 0.49 10.6 0.0 2.4 1 1 1 2 2 2 2 RNase H Exo_endo_phos PF03372.23 KKF92347.1 - 0.076 12.5 0.0 0.83 9.1 0.0 2.3 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family HIT PF01230.23 KKF92348.1 - 1e-13 51.9 1.1 1.1e-13 51.8 1.1 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KKF92348.1 - 0.00012 22.5 0.8 0.00014 22.3 0.8 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KKF92348.1 - 0.00034 20.5 0.1 0.00036 20.4 0.1 1.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 ICAT PF06384.11 KKF92348.1 - 0.0039 17.4 0.0 0.0047 17.2 0.0 1.1 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT LppA PF16708.5 KKF92348.1 - 0.046 13.6 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium CSTF2_hinge PF14327.6 KKF92348.1 - 0.085 13.3 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 CRAL_TRIO PF00650.20 KKF92349.1 - 1e-36 126.1 0.0 7e-35 120.1 0.0 2.5 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKF92349.1 - 1.5e-13 50.7 0.4 1.5e-13 50.7 0.4 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KKF92349.1 - 4e-07 30.3 0.0 9.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DNA_pol_A_exoN PF18305.1 KKF92349.1 - 0.0059 16.9 0.1 0.013 15.8 0.1 1.6 1 0 0 1 1 1 1 3' to 5' exonuclease C-terminal domain Aminotran_1_2 PF00155.21 KKF92350.1 - 0.022 14.0 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Arginosuc_synth PF00764.19 KKF92351.1 - 6.4e-150 499.8 0.0 7.3e-150 499.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KKF92351.1 - 0.021 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KKF92351.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase TRAM_LAG1_CLN8 PF03798.16 KKF92352.1 - 7.3e-38 130.3 21.0 7.3e-38 130.3 21.0 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KKF92352.1 - 7.5e-26 89.6 0.4 7.5e-26 89.6 0.4 2.5 2 0 0 2 2 2 1 TRAM1-like protein DUF5345 PF17280.2 KKF92352.1 - 2 8.4 0.0 2 8.4 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5345) IGPS PF00218.21 KKF92353.1 - 4.3e-94 314.4 0.0 1.6e-93 312.6 0.0 1.8 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KKF92353.1 - 1.4e-47 162.0 0.0 1.6e-43 148.7 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KKF92353.1 - 2.6e-46 157.8 0.1 1.5e-45 155.3 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKF92353.1 - 4.7e-05 23.2 1.6 0.00036 20.4 0.7 2.6 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.19 KKF92353.1 - 0.00032 20.5 0.4 0.017 14.9 0.1 3.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.18 KKF92353.1 - 0.047 12.7 0.4 0.11 11.5 0.4 1.6 1 0 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 KKF92353.1 - 0.12 11.8 0.3 0.6 9.5 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein NACHT_N PF17100.5 KKF92354.1 - 5.9e-41 140.7 11.2 4.4e-25 88.9 0.2 2.9 2 1 1 3 3 3 2 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KKF92354.1 - 4.1e-06 26.8 0.5 1.6e-05 24.9 0.0 2.2 2 1 0 2 2 2 1 NACHT domain RTX PF02382.15 KKF92354.1 - 0.047 13.4 3.3 0.57 9.8 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain in RTX protein Sh_2 PF17512.2 KKF92354.1 - 0.054 13.3 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein DUF87 PF01935.17 KKF92354.1 - 0.17 11.9 5.3 0.36 10.9 1.5 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain DUF445 PF04286.12 KKF92354.1 - 0.2 11.4 7.8 0.36 10.6 7.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) AAA_11 PF13086.6 KKF92354.1 - 0.5 10.1 6.7 0.78 9.5 0.0 2.6 1 1 1 2 2 2 0 AAA domain tRNA-synt_1 PF00133.22 KKF92355.1 - 1.4e-206 687.4 0.0 1.9e-206 687.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKF92355.1 - 2.9e-23 82.5 0.0 8.6e-23 81.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKF92355.1 - 5.4e-13 48.5 0.4 0.00015 20.7 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KKF92355.1 - 0.0025 17.2 0.0 0.075 12.4 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Lipase_3 PF01764.25 KKF92356.1 - 1.8e-13 50.6 0.0 6.5e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Corona_nucleoca PF00937.18 KKF92356.1 - 0.17 10.9 2.5 0.31 10.0 2.5 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Pkinase PF00069.25 KKF92357.1 - 2.4e-59 200.9 0.0 2.9e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92357.1 - 2.8e-21 76.0 0.0 3.8e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF92357.1 - 1.4e-06 27.8 0.0 4.2e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KKF92357.1 - 0.0082 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKF92357.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIF4G_like PF09088.11 KKF92358.1 - 6.6e-87 290.2 0.6 1e-86 289.6 0.6 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KKF92358.1 - 1.4e-46 159.2 0.0 5.1e-46 157.3 0.0 2.0 1 1 0 1 1 1 1 MIF4G like HpaB PF03241.13 KKF92358.1 - 0.16 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal RRM_1 PF00076.22 KKF92359.1 - 5.7e-33 112.6 0.0 1.5e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KKF92359.1 - 0.0031 17.2 0.2 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_7 PF16367.5 KKF92359.1 - 0.0067 16.5 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KKF92359.1 - 0.053 13.1 0.1 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas2CT1978 PF09707.10 KKF92359.1 - 0.11 12.6 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) NmrA PF05368.13 KKF92360.1 - 5.2e-22 78.6 0.2 8e-22 77.9 0.2 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKF92360.1 - 4.6e-15 56.0 0.0 5.5e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKF92360.1 - 5.4e-05 22.8 0.4 0.00013 21.6 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KKF92360.1 - 0.00012 22.5 0.6 0.0002 21.8 0.6 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KKF92360.1 - 0.00014 22.1 0.1 0.00026 21.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KKF92360.1 - 0.0012 18.0 0.1 0.0018 17.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.23 KKF92360.1 - 0.0056 16.8 0.3 0.012 15.6 0.3 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 KKF92360.1 - 0.0062 16.0 0.7 0.013 14.9 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.20 KKF92360.1 - 0.011 15.9 0.3 0.023 14.8 0.3 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 KKF92360.1 - 0.016 14.6 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CoA_binding_2 PF13380.6 KKF92360.1 - 0.017 15.6 0.2 0.032 14.7 0.2 1.5 1 0 0 1 1 1 0 CoA binding domain 3HCDH_N PF02737.18 KKF92360.1 - 0.042 13.7 0.5 0.064 13.1 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KKF92360.1 - 0.056 13.7 0.3 0.13 12.5 0.2 1.7 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_2 PF03446.15 KKF92360.1 - 0.071 13.3 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_binding PF02629.19 KKF92360.1 - 0.11 13.2 1.2 0.31 11.8 1.2 1.7 1 0 0 1 1 1 0 CoA binding domain THF_DHG_CYH_C PF02882.19 KKF92360.1 - 0.14 11.5 0.4 0.39 10.0 0.4 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KKF92360.1 - 0.15 12.5 0.4 0.41 11.1 0.2 1.8 2 1 0 2 2 1 0 Putative NAD(P)-binding DXP_reductoisom PF02670.16 KKF92360.1 - 0.32 11.7 2.8 7.5 7.3 0.3 2.5 2 1 1 3 3 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lactamase_B PF00753.27 KKF92361.1 - 4.9e-10 39.8 0.1 0.0013 18.8 0.1 2.3 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKF92361.1 - 1.4e-05 24.7 0.0 2.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HLH PF00010.26 KKF92362.1 - 7.2e-11 41.9 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NRBF2 PF08961.10 KKF92362.1 - 0.0079 15.8 5.5 0.026 14.1 0.3 2.2 2 1 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 KKF92362.1 - 0.034 14.6 0.8 0.034 14.6 0.8 2.5 2 1 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KKF92362.1 - 0.19 11.5 0.1 0.19 11.5 0.1 1.9 2 1 1 3 3 3 0 Septum formation initiator CP12 PF02672.15 KKF92362.1 - 0.21 12.4 0.3 0.21 12.4 0.3 2.2 2 1 0 2 2 2 0 CP12 domain HALZ PF02183.18 KKF92362.1 - 0.23 11.7 1.9 0.37 11.1 0.4 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2981 PF11200.8 KKF92362.1 - 0.36 10.5 1.0 0.47 10.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) RRP14 PF15459.6 KKF92362.1 - 1.1 9.8 6.2 5.2 7.8 0.0 2.9 3 0 0 3 3 3 0 60S ribosome biogenesis protein Rrp14 Jnk-SapK_ap_N PF09744.9 KKF92362.1 - 3.2 8.0 10.0 2 8.6 0.4 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Aldo_ket_red PF00248.21 KKF92363.1 - 2.1e-48 165.0 0.0 1.5e-46 158.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HIT PF01230.23 KKF92364.1 - 5.9e-18 65.4 0.0 1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KKF92364.1 - 7.3e-05 23.2 0.0 0.00014 22.3 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KKF92364.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 DNA_RNApol_7kD PF03604.13 KKF92365.1 - 1.2e-10 40.8 3.9 2e-10 40.2 3.9 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.12 KKF92365.1 - 0.0033 16.9 2.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding zinc_ribbon_6 PF14599.6 KKF92365.1 - 0.051 13.6 1.5 0.074 13.1 1.5 1.2 1 0 0 1 1 1 0 Zinc-ribbon Ribosomal_L37ae PF01780.19 KKF92365.1 - 0.06 13.4 0.1 0.069 13.2 0.1 1.2 1 0 0 1 1 1 0 Ribosomal L37ae protein family GFA PF04828.14 KKF92365.1 - 0.1 12.9 2.2 1.9 8.9 0.5 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 KKF92365.1 - 0.18 12.3 3.9 4.6 7.8 0.7 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain ATP_bind_1 PF03029.17 KKF92366.1 - 1.5e-70 237.7 0.0 1.2e-38 133.2 0.0 2.4 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KKF92366.1 - 5.6e-05 23.2 0.0 0.02 15.0 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKF92366.1 - 7.9e-05 22.3 0.0 0.0069 15.9 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KKF92366.1 - 0.00054 19.2 0.5 0.018 14.2 0.0 2.6 3 1 0 3 3 3 1 G-protein alpha subunit AAA_24 PF13479.6 KKF92366.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 KKF92366.1 - 0.0019 18.0 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KKF92366.1 - 0.0025 17.1 0.0 0.006 15.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 KKF92366.1 - 0.0026 17.4 0.0 0.18 11.4 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KKF92366.1 - 0.0031 17.9 0.0 0.0031 17.9 0.0 2.1 2 2 0 2 2 1 1 AAA ATPase domain cobW PF02492.19 KKF92366.1 - 0.0046 16.6 0.0 1.2 8.7 0.0 2.7 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KKF92366.1 - 0.0056 16.2 0.0 0.081 12.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B NB-ARC PF00931.22 KKF92366.1 - 0.0067 15.6 0.0 0.033 13.4 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KKF92366.1 - 0.011 16.0 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain CLN3 PF02487.17 KKF92366.1 - 0.012 14.7 0.1 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 CLN3 protein Roc PF08477.13 KKF92366.1 - 0.015 15.5 0.0 5 7.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KKF92366.1 - 0.016 15.1 0.0 6 6.7 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 KKF92366.1 - 0.017 15.3 2.3 0.019 15.2 0.1 2.3 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.6 KKF92366.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KKF92366.1 - 0.022 13.8 0.1 3.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 KKF92366.1 - 0.024 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF4407 PF14362.6 KKF92366.1 - 0.061 12.7 8.1 0.015 14.7 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Arf PF00025.21 KKF92366.1 - 0.082 12.3 0.0 6.2 6.2 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family CLP1_P PF16575.5 KKF92366.1 - 0.1 12.3 0.0 0.93 9.3 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Methyltransf_32 PF13679.6 KKF92366.1 - 0.13 12.2 1.2 0.71 9.9 0.4 2.2 2 0 0 2 2 2 0 Methyltransferase domain SRPRB PF09439.10 KKF92366.1 - 0.15 11.5 0.7 17 4.8 0.0 2.6 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit HAUS6_N PF14661.6 KKF92366.1 - 0.8 9.2 8.4 0.94 9.0 2.8 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus RNA_pol_Rpc4 PF05132.14 KKF92366.1 - 1.1 9.7 9.6 0.69 10.3 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 AAA_23 PF13476.6 KKF92366.1 - 3.4 8.1 10.3 52 4.2 10.3 2.7 1 1 0 1 1 1 0 AAA domain FAM60A PF15396.6 KKF92366.1 - 4.5 7.2 7.7 5.1 7.0 3.8 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DUF87 PF01935.17 KKF92366.1 - 5.8 6.9 6.8 3.3 7.8 1.0 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain BRE1 PF08647.11 KKF92366.1 - 9.8 6.3 12.6 0.5 10.5 6.8 1.8 2 0 0 2 2 1 0 BRE1 E3 ubiquitin ligase CwfJ_C_2 PF04676.14 KKF92367.1 - 2e-27 96.0 0.3 6.5e-27 94.3 0.3 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KKF92367.1 - 6.4e-25 87.4 0.0 1.1e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Latarcin PF10279.9 KKF92367.1 - 0.007 16.7 0.2 0.04 14.3 0.0 2.3 2 0 0 2 2 2 1 Latarcin precursor FumaraseC_C PF10415.9 KKF92367.1 - 0.12 12.8 0.5 2.8 8.4 0.1 2.8 2 0 0 2 2 2 0 Fumarase C C-terminus Dsh_C PF12316.8 KKF92367.1 - 1.3 9.4 8.8 33 4.8 5.6 2.6 2 1 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal NACHT PF05729.12 KKF92369.1 - 1.9e-09 37.6 0.0 4.1e-09 36.6 0.0 1.5 2 0 0 2 2 2 1 NACHT domain NACHT_N PF17100.5 KKF92369.1 - 7e-08 32.6 0.1 1.1e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase RNA_helicase PF00910.22 KKF92369.1 - 0.029 14.8 0.1 0.08 13.3 0.0 1.9 2 1 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 KKF92369.1 - 0.035 14.4 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KKF92369.1 - 0.036 13.9 0.9 0.28 10.9 0.0 2.0 1 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KKF92369.1 - 0.037 13.3 0.2 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KKF92369.1 - 0.04 14.2 0.1 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Col_cuticle_N PF01484.17 KKF92369.1 - 0.41 10.8 1.4 6.3 7.0 0.3 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain ING PF12998.7 KKF92372.1 - 1.5e-05 25.5 1.8 0.0001 22.8 0.0 3.2 3 0 0 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding Collagen PF01391.18 KKF92372.1 - 0.0061 16.3 13.3 0.0061 16.3 13.3 2.8 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) DPM2 PF07297.12 KKF92374.1 - 2e-29 101.7 1.8 2.2e-29 101.5 1.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KKF92374.1 - 0.00047 20.1 1.0 0.00051 20.0 1.0 1.1 1 0 0 1 1 1 1 PIG-P COX14 PF14880.6 KKF92374.1 - 0.0008 19.2 3.8 0.0032 17.3 0.1 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly CAAD PF14159.6 KKF92374.1 - 0.038 13.8 0.4 0.064 13.1 0.0 1.5 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase LapA_dom PF06305.11 KKF92374.1 - 0.067 13.0 0.2 0.067 13.0 0.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4229 PF14012.6 KKF92374.1 - 0.5 10.5 5.3 1.8 8.7 5.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4229) SecE PF00584.20 KKF92377.1 - 4.2e-16 58.6 0.0 5.1e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF3784 PF12650.7 KKF92377.1 - 0.066 13.4 0.0 0.08 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) RVT_1 PF00078.27 KKF92378.1 - 1.1e-32 113.4 0.0 1.6e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KKF92378.1 - 5.1e-05 23.2 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KKF92379.1 - 1.8e-17 63.5 0.2 3.8e-17 62.5 0.1 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KKF92379.1 - 3.4e-05 23.8 0.0 9.1e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 KKF92380.1 - 1.4e-46 159.0 0.0 2e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92380.1 - 5.1e-25 88.2 0.0 8e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KKF92380.1 - 0.0051 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KKF92380.1 - 0.011 15.6 0.3 0.081 12.8 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KKF92380.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KKF92380.1 - 0.065 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hira PF07569.11 KKF92381.1 - 1.1e-81 273.9 0.4 2e-81 273.0 0.0 1.7 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 KKF92381.1 - 2e-31 107.5 25.0 2.3e-06 28.2 0.0 8.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92381.1 - 5.3e-15 55.5 0.1 0.24 11.7 0.0 6.5 4 1 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KKF92381.1 - 8e-10 38.3 0.5 8e-10 38.3 0.5 2.3 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 KKF92381.1 - 1.8e-05 24.5 0.3 8.9 6.4 0.0 5.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KKF92381.1 - 2.2e-05 23.6 0.4 0.1 11.6 0.0 4.1 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KKF92381.1 - 0.012 13.6 0.0 0.025 12.6 0.0 1.4 1 0 0 1 1 1 0 IKI3 family Med3 PF11593.8 KKF92381.1 - 0.85 8.7 9.6 1.9 7.6 9.6 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-U1 PF06220.12 KKF92382.1 - 2.2e-09 36.9 0.9 3.4e-09 36.3 0.9 1.3 1 0 0 1 1 1 1 U1 zinc finger ABC_tran_Xtn PF12848.7 KKF92382.1 - 0.021 14.8 4.2 0.35 10.9 0.2 2.7 3 0 0 3 3 3 0 ABC transporter MHYT PF03707.16 KKF92383.1 - 7.4e-15 54.9 18.1 2.7e-08 33.9 1.1 3.8 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat DUF4293 PF14126.6 KKF92383.1 - 2.3 8.4 4.7 4.8 7.4 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) WD40 PF00400.32 KKF92384.1 - 1.9e-68 224.7 29.1 3.9e-09 37.0 0.1 10.4 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92384.1 - 1.6e-34 118.1 0.7 3.4e-07 30.5 0.0 7.6 3 2 4 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF92384.1 - 1.3e-13 50.6 8.6 0.028 13.4 0.1 7.9 2 2 5 8 8 8 5 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KKF92384.1 - 9.3e-11 41.9 0.0 2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.11 KKF92384.1 - 1.4e-07 31.6 0.0 0.033 14.1 0.0 4.3 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.6 KKF92384.1 - 7.2e-06 26.5 0.0 2.9e-05 24.5 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain Nup160 PF11715.8 KKF92384.1 - 1.6e-05 23.8 7.9 0.23 10.1 0.1 5.3 1 1 4 6 6 6 2 Nucleoporin Nup120/160 Helo_like_N PF17111.5 KKF92384.1 - 3.8e-05 23.2 0.3 8.2e-05 22.1 0.3 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SGL PF08450.12 KKF92384.1 - 0.00054 19.6 1.2 0.1 12.1 0.1 3.8 4 1 0 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KKF92384.1 - 0.00098 19.0 9.3 13 5.9 0.1 7.6 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat AAA_22 PF13401.6 KKF92384.1 - 0.001 19.4 0.0 0.003 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Frtz PF11768.8 KKF92384.1 - 0.0026 16.1 0.1 3.5 5.8 0.0 3.7 3 1 1 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KKF92384.1 - 0.0092 15.3 0.0 5.6 6.2 0.1 3.5 3 1 1 4 4 4 1 WD40-like domain Nbas_N PF15492.6 KKF92384.1 - 0.015 14.7 8.8 16 4.7 0.0 6.6 3 3 4 8 8 8 0 Neuroblastoma-amplified sequence, N terminal AAA_33 PF13671.6 KKF92384.1 - 0.033 14.3 0.0 0.093 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKF92384.1 - 0.055 14.0 0.0 0.8 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKF92384.1 - 0.057 13.8 0.4 0.19 12.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KKF92384.1 - 0.064 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Met_10 PF02475.16 KKF92385.1 - 3.6e-05 23.6 0.0 0.00011 22.0 0.0 1.9 1 1 0 1 1 1 1 Met-10+ like-protein EF-hand_6 PF13405.6 KKF92386.1 - 4.9e-08 32.3 3.3 0.00021 21.0 0.9 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KKF92386.1 - 4.8e-05 23.7 4.2 4.8e-05 23.7 4.2 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KKF92386.1 - 0.0049 16.3 2.7 0.43 10.3 0.2 2.4 2 0 0 2 2 2 2 EF hand Alk_phosphatase PF00245.20 KKF92387.1 - 4.8e-65 220.1 0.1 5.5e-64 216.6 0.1 2.0 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 KKF92387.1 - 1e-08 35.2 0.3 2.1e-08 34.1 0.3 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKF92387.1 - 9.2e-05 22.0 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KKF92387.1 - 0.0022 16.7 0.3 0.0033 16.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KKF92387.1 - 0.0052 16.2 1.3 0.04 13.3 0.2 2.2 2 0 0 2 2 2 1 Metalloenzyme superfamily PglZ PF08665.12 KKF92387.1 - 0.012 15.7 0.4 0.023 14.8 0.4 1.4 1 0 0 1 1 1 0 PglZ domain Aldedh PF00171.22 KKF92388.1 - 4.5e-141 470.5 0.0 5.6e-141 470.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Romo1 PF10247.9 KKF92388.1 - 0.029 14.7 2.6 0.062 13.7 2.6 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 LuxC PF05893.14 KKF92388.1 - 0.034 13.2 0.0 0.094 11.7 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Adaptin_N PF01602.20 KKF92389.1 - 1.3e-90 304.5 8.6 2.3e-90 303.6 8.6 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KKF92389.1 - 2.3e-60 202.5 0.2 5.2e-60 201.4 0.2 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KKF92389.1 - 8e-57 190.7 0.0 2.6e-56 189.1 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KKF92389.1 - 9.1e-15 55.1 4.2 6.2e-11 42.6 0.1 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKF92389.1 - 4.6e-07 30.1 10.6 0.0017 18.7 0.0 5.8 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 KKF92389.1 - 0.0003 20.8 0.3 0.92 9.9 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 KKF92389.1 - 0.00041 20.5 0.0 0.0028 17.8 0.0 2.4 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform AP4E_app_platf PF14807.6 KKF92389.1 - 0.053 13.9 0.3 0.18 12.2 0.3 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 KKF92389.1 - 0.38 11.3 1.3 25 5.5 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat HlyIII PF03006.20 KKF92390.1 - 1.8e-45 155.4 6.3 2.4e-45 155.0 6.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 KKF92390.1 - 0.045 13.8 0.1 0.099 12.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Pol_alpha_B_N PF08418.10 KKF92391.1 - 0.22 11.5 3.9 0.32 10.9 3.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal TPR_19 PF14559.6 KKF92392.1 - 1.5e-05 25.4 0.3 0.0013 19.2 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_assoc_2 PF16193.5 KKF92392.1 - 0.00087 19.6 0.5 0.004 17.5 0.4 2.1 1 1 1 2 2 2 1 AAA C-terminal domain TPR_21 PF09976.9 KKF92392.1 - 0.0026 17.5 0.4 0.006 16.3 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain YfdX PF10938.8 KKF92392.1 - 0.034 14.1 0.8 0.27 11.1 0.6 2.4 1 1 0 1 1 1 0 YfdX protein TPR_2 PF07719.17 KKF92392.1 - 0.042 14.0 0.1 33 4.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 KKF92392.1 - 0.065 13.4 0.6 0.27 11.4 0.6 2.1 1 1 0 1 1 1 0 HemY protein N-terminus ANAPC3 PF12895.7 KKF92392.1 - 0.094 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KKF92392.1 - 0.53 11.1 7.1 2.2 9.1 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKF92393.1 - 5.6e-35 119.5 12.8 2.5e-11 43.7 0.6 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KKF92393.1 - 1.5e-26 91.5 14.1 1.3e-06 28.1 0.1 5.7 6 0 0 6 6 5 5 Tetratricopeptide repeat NB-ARC PF00931.22 KKF92393.1 - 8.5e-13 48.1 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 KKF92393.1 - 1.2e-12 47.0 0.2 0.2 11.9 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF92393.1 - 1.7e-12 47.4 4.2 0.0077 16.4 0.1 4.7 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KKF92393.1 - 1.9e-12 46.2 4.6 0.091 12.8 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKF92393.1 - 2.3e-12 47.2 11.9 0.041 14.4 0.3 5.1 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKF92393.1 - 1.3e-11 44.3 8.4 0.049 14.5 0.1 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KKF92393.1 - 3.1e-11 43.2 0.4 0.21 12.3 0.1 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 KKF92393.1 - 1.3e-09 38.2 13.7 0.081 13.3 0.5 5.2 1 1 4 5 5 5 4 Tetratricopeptide repeat DUF4248 PF14053.6 KKF92393.1 - 4.7e-08 33.0 0.9 1.2 9.2 0.0 4.5 4 0 0 4 4 4 2 Domain of unknown function (DUF4248) TPR_2 PF07719.17 KKF92393.1 - 1.5e-07 31.0 0.0 0.073 13.2 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKF92393.1 - 3e-06 27.2 4.8 3.1 8.4 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KKF92393.1 - 3.6e-06 27.1 6.9 4.8 8.1 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat YfdX PF10938.8 KKF92393.1 - 1.2e-05 25.3 14.4 0.68 9.9 0.2 5.2 3 1 3 6 6 5 3 YfdX protein TPR_1 PF00515.28 KKF92393.1 - 0.00033 20.3 0.1 0.17 11.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKF92393.1 - 0.00041 20.9 7.0 0.13 13.0 0.1 4.7 2 1 2 5 5 5 1 Tetratricopeptide repeat PPR PF01535.20 KKF92393.1 - 0.00047 20.2 0.0 83 3.8 0.0 5.0 5 0 0 5 5 5 0 PPR repeat AAA_16 PF13191.6 KKF92393.1 - 0.0011 19.4 0.2 0.0011 19.4 0.2 3.2 3 2 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KKF92393.1 - 0.0012 18.8 0.1 0.008 16.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain ACTL7A_N PF16840.5 KKF92393.1 - 0.0034 17.4 1.0 0.4 10.8 0.1 3.3 1 1 2 3 3 3 1 Actin-like protein 7A N-terminus BTAD PF03704.17 KKF92393.1 - 0.0076 16.7 10.3 1.6 9.1 1.6 3.8 1 1 2 3 3 3 1 Bacterial transcriptional activator domain AAA_22 PF13401.6 KKF92393.1 - 0.01 16.1 0.2 0.086 13.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain TPR_9 PF13371.6 KKF92393.1 - 0.012 15.8 4.8 5.8 7.1 0.2 5.0 2 1 3 5 5 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KKF92393.1 - 0.016 15.6 8.6 11 6.4 0.9 4.6 1 1 3 4 4 4 0 Alkyl sulfatase dimerisation SRP54 PF00448.22 KKF92393.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Lectin_N PF03954.14 KKF92393.1 - 0.031 14.0 9.7 13 5.5 0.1 4.2 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain IstB_IS21 PF01695.17 KKF92393.1 - 0.043 13.5 0.2 0.29 10.8 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase PF06745.13 KKF92393.1 - 0.085 12.2 0.1 0.38 10.1 0.0 2.1 2 0 0 2 2 1 0 KaiC TPR_21 PF09976.9 KKF92393.1 - 0.096 12.4 13.1 0.44 10.2 4.7 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain SgrR_N PF12793.7 KKF92393.1 - 0.11 12.8 4.5 24 5.2 0.1 3.8 1 1 2 3 3 3 0 Sugar transport-related sRNA regulator N-term SnAC PF14619.6 KKF92393.1 - 0.28 11.8 1.6 49 4.6 0.1 3.2 1 1 2 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex HECT PF00632.25 KKF92394.1 - 8.3e-33 114.2 0.0 1.3e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MMR_HSR1 PF01926.23 KKF92394.1 - 1.2e-12 47.9 0.0 3.4e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KKF92394.1 - 8.7e-07 29.1 0.3 0.0035 17.4 0.1 3.3 3 0 0 3 3 3 2 Dynamin family FtsK_SpoIIIE PF01580.18 KKF92394.1 - 0.02 14.3 0.0 0.068 12.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family FAD_binding_1 PF00667.20 KKF92395.1 - 6.4e-65 218.8 0.0 1e-64 218.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KKF92395.1 - 1.5e-09 38.5 0.0 4.1e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 KKF92395.1 - 1.7e-07 31.4 0.1 5.8e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 KKF92395.1 - 9.2e-07 29.1 0.0 2.6e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KKF92395.1 - 0.0074 16.2 0.1 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain POR_N PF01855.19 KKF92395.1 - 0.022 14.5 0.2 0.041 13.6 0.2 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Pkinase PF00069.25 KKF92396.1 - 1.7e-70 237.4 0.0 2.2e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92396.1 - 3.1e-30 105.3 0.0 4.3e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF92396.1 - 0.00058 19.3 0.0 0.0012 18.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KKF92396.1 - 0.0016 17.5 0.0 0.025 13.5 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KKF92396.1 - 0.008 16.1 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KKF92396.1 - 0.059 12.4 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 AA_permease PF00324.21 KKF92400.1 - 3.2e-104 349.2 51.9 3.6e-104 349.0 51.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKF92400.1 - 1.3e-28 100.1 54.9 1.6e-28 99.7 54.9 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_47 PF01532.20 KKF92401.1 - 7.6e-113 377.8 0.0 1e-112 377.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DNA_binding_2 PF13724.6 KKF92401.1 - 0.19 12.2 1.1 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 DNA-binding domain Pribosyltran PF00156.27 KKF92402.1 - 6.6e-17 61.5 0.0 9.7e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKF92402.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Aconitase_2_N PF06434.13 KKF92402.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus Ank_2 PF12796.7 KKF92403.1 - 1.8e-31 108.5 0.5 5.8e-10 39.6 0.0 5.0 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKF92403.1 - 3.1e-28 97.8 3.6 3e-07 30.8 0.0 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KKF92403.1 - 2.5e-27 94.1 7.1 1.6e-05 25.1 0.0 7.9 6 1 1 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 KKF92403.1 - 7.9e-27 90.4 0.2 0.00037 20.7 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 KKF92403.1 - 2.6e-23 81.7 6.8 1.1e-07 31.9 0.1 5.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) AAA_16 PF13191.6 KKF92403.1 - 1.8e-07 31.7 0.1 1.8e-06 28.4 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain Helo_like_N PF17111.5 KKF92403.1 - 9.1e-07 28.4 0.1 2.6e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KKF92403.1 - 0.00012 22.0 0.4 0.00056 19.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KKF92403.1 - 0.15 12.5 0.0 0.49 10.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3435 PF11917.8 KKF92404.1 - 1.5e-26 93.3 0.7 2.5e-26 92.6 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-BED PF02892.15 KKF92404.1 - 0.29 11.2 1.4 0.49 10.4 0.0 2.2 3 0 0 3 3 3 0 BED zinc finger Hormone_4 PF00220.17 KKF92405.1 - 1 9.5 3.2 2.5 8.3 1.3 2.3 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain Pyr_redox_2 PF07992.14 KKF92406.1 - 7.3e-52 176.4 0.0 9.4e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKF92406.1 - 3.3e-10 40.4 0.0 1.5e-09 38.3 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKF92406.1 - 0.01 15.1 0.6 3.7 6.7 0.0 2.4 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 KKF92406.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Amidohydro_1 PF01979.20 KKF92407.1 - 1.5e-11 44.2 0.4 6.5e-09 35.6 0.1 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_3 PF07969.11 KKF92407.1 - 3.3e-09 36.7 3.4 0.0029 17.2 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family Mid2 PF04478.12 KKF92408.1 - 2.2e-05 24.3 1.9 2.2e-05 24.3 1.9 2.9 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor DUF4834 PF16118.5 KKF92408.1 - 5.4 8.0 6.4 26 5.9 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) SRP-alpha_N PF04086.13 KKF92408.1 - 8.2 6.2 14.5 15 5.4 14.5 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAM2 PF07145.15 KKF92409.1 - 0.00019 20.9 10.1 0.23 11.2 2.3 3.7 3 0 0 3 3 3 3 Ataxin-2 C-terminal region COX6A PF02046.15 KKF92412.1 - 1.6e-47 160.6 0.7 1.9e-47 160.4 0.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa CrgA PF06781.12 KKF92412.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Cell division protein CrgA ANAPC5 PF12862.7 KKF92413.1 - 9.7e-22 76.9 1.0 9.7e-22 76.9 1.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 KKF92413.1 - 5.8e-07 29.7 10.3 0.056 13.7 0.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KKF92413.1 - 0.00052 19.8 2.9 4.6 7.2 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKF92413.1 - 0.0027 18.4 3.7 34 5.6 0.0 5.5 6 0 0 6 6 4 0 Tetratricopeptide repeat CDC45 PF02724.14 KKF92413.1 - 0.0075 14.6 1.8 0.011 14.0 1.8 1.2 1 0 0 1 1 1 1 CDC45-like protein RR_TM4-6 PF06459.12 KKF92413.1 - 0.043 13.7 2.4 0.072 12.9 2.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TPR_19 PF14559.6 KKF92413.1 - 0.067 13.7 8.7 1.8 9.1 0.3 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat SDA1 PF05285.12 KKF92413.1 - 0.25 10.7 9.3 0.38 10.1 9.3 1.1 1 0 0 1 1 1 0 SDA1 DUF3408 PF11888.8 KKF92413.1 - 0.44 10.7 5.2 0.83 9.8 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF4746 PF15928.5 KKF92413.1 - 0.53 9.7 7.3 0.83 9.0 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TRAP_alpha PF03896.16 KKF92413.1 - 0.84 8.8 5.9 1.4 8.1 5.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cnd2 PF05786.14 KKF92413.1 - 1.1 7.8 8.6 1.6 7.3 8.6 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Sporozoite_P67 PF05642.11 KKF92413.1 - 1.6 6.7 4.8 2.6 6.0 4.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 KKF92413.1 - 2.4 8.0 11.0 0.23 11.3 6.0 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.12 KKF92413.1 - 5.1 5.2 13.5 8.2 4.5 13.5 1.2 1 0 0 1 1 1 0 Nop14-like family ANTH PF07651.16 KKF92414.1 - 7.9e-76 254.7 0.0 7.9e-76 254.7 0.0 2.8 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.17 KKF92414.1 - 7e-55 185.5 9.4 7e-55 185.5 9.4 5.6 3 1 3 6 6 6 2 I/LWEQ domain ENTH PF01417.20 KKF92414.1 - 0.022 14.8 0.1 0.2 11.7 0.0 2.7 2 1 0 2 2 2 0 ENTH domain NmrA PF05368.13 KKF92415.1 - 4.2e-19 69.0 1.7 1.1e-18 67.6 0.9 1.8 1 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KKF92415.1 - 3.9e-16 59.5 0.0 5.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKF92415.1 - 0.0046 16.5 0.2 0.011 15.3 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 KKF92415.1 - 0.0063 16.3 0.3 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.20 KKF92415.1 - 0.011 15.9 0.4 0.022 14.8 0.4 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 KKF92415.1 - 0.011 16.0 0.3 0.019 15.2 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.24 KKF92415.1 - 0.012 16.1 0.7 0.023 15.2 0.7 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KKF92415.1 - 0.014 15.7 0.6 0.033 14.4 0.6 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KKF92415.1 - 0.023 14.8 0.8 0.056 13.5 0.8 1.8 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KKF92415.1 - 0.025 15.3 3.1 0.9 10.3 0.0 2.6 2 1 1 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RmlD_sub_bind PF04321.17 KKF92415.1 - 0.051 12.7 0.1 0.08 12.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 KKF92415.1 - 0.12 13.0 0.9 0.3 11.7 0.4 2.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Prefoldin_2 PF01920.20 KKF92417.1 - 2.2e-23 82.2 6.0 2.8e-23 81.9 6.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KKF92417.1 - 0.22 11.4 9.2 0.075 12.9 1.9 2.2 1 1 1 2 2 2 0 Prefoldin subunit Spc24 PF08286.11 KKF92417.1 - 0.36 11.1 9.7 0.67 10.2 1.2 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 5_nucleotid PF05761.14 KKF92417.1 - 0.43 9.4 3.3 0.66 8.8 3.3 1.3 1 1 0 1 1 1 0 5' nucleotidase family FAM167 PF11652.8 KKF92417.1 - 0.47 11.0 6.5 20 5.7 0.1 3.1 1 1 1 3 3 3 0 FAM167 FIN1 PF17300.2 KKF92417.1 - 0.69 9.4 7.6 0.79 9.2 7.6 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 DUF1664 PF07889.12 KKF92417.1 - 0.86 9.7 3.2 9.2 6.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PKS_DE PF18369.1 KKF92417.1 - 3.9 8.1 6.4 1.7 9.3 0.4 2.8 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain KfrA_N PF11740.8 KKF92417.1 - 4.4 8.0 8.2 0.46 11.2 2.0 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term PKcGMP_CC PF16808.5 KKF92417.1 - 7.5 6.5 9.9 0.6 10.0 0.8 3.2 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CBFD_NFYB_HMF PF00808.23 KKF92418.1 - 0.0002 21.6 0.0 0.00025 21.3 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KKF92418.1 - 0.0004 20.5 0.0 0.00046 20.3 0.0 1.1 1 0 0 1 1 1 1 CENP-W protein RNA_pol_I_A49 PF06870.12 KKF92418.1 - 0.063 12.1 0.0 0.069 12.0 0.0 1.0 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor DUF383 PF04063.14 KKF92420.1 - 4.1e-66 222.3 0.7 8.7e-65 218.0 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KKF92420.1 - 1.3e-16 60.2 0.5 2.8e-16 59.1 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_2 PF13646.6 KKF92420.1 - 0.013 15.8 0.1 0.17 12.3 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats Bystin PF05291.11 KKF92421.1 - 1.7e-118 395.2 0.0 2.2e-118 394.8 0.0 1.1 1 0 0 1 1 1 1 Bystin CDC73_C PF05179.14 KKF92422.1 - 3.9e-47 159.9 0.0 5.6e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal RGS PF00615.19 KKF92423.1 - 1.8e-34 118.5 1.1 3.8e-34 117.5 0.3 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KKF92423.1 - 1.8e-22 79.1 0.0 7.1e-19 67.6 0.0 3.6 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 KKF92423.1 - 0.0064 16.6 0.1 0.38 10.8 0.0 2.3 2 0 0 2 2 2 1 Replication-relaxation MerR_2 PF13591.6 KKF92423.1 - 0.12 12.3 0.1 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 MerR HTH family regulatory protein OTT_1508_deam PF14441.6 KKF92426.1 - 1.9e-14 53.4 2.7 3.7e-14 52.5 2.7 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Tyrosinase PF00264.20 KKF92427.1 - 9.9e-43 147.0 0.4 1.4e-42 146.5 0.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans PF04082.18 KKF92428.1 - 3.9e-21 75.3 0.1 7.7e-21 74.3 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_16 PF00722.21 KKF92429.1 - 4.9e-09 35.9 0.0 2.9e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KKF92429.1 - 0.012 14.0 1.4 0.018 13.5 0.7 1.6 2 0 0 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) zf-CCHC_2 PF13696.6 KKF92431.1 - 0.0002 21.1 1.2 0.00034 20.4 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KKF92431.1 - 0.0004 20.3 1.4 0.00073 19.5 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle GRP PF07172.11 KKF92431.1 - 0.00043 20.9 5.1 0.0014 19.3 5.1 1.9 1 0 0 1 1 1 1 Glycine rich protein family TMEM132D_N PF15705.5 KKF92431.1 - 0.024 14.5 0.4 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term zf-CCHC_4 PF14392.6 KKF92431.1 - 0.31 10.8 1.3 0.7 9.7 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle PI-PLC-X PF00388.19 KKF92432.1 - 6.9e-11 41.9 0.0 1.8e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-X PF00388.19 KKF92433.1 - 2.7e-09 36.8 0.0 4.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-X PF00388.19 KKF92434.1 - 1.3e-09 37.8 0.0 2.5e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain TatD_DNase PF01026.21 KKF92436.1 - 2.7e-26 92.5 0.0 1.3e-25 90.3 0.0 1.9 1 1 0 1 1 1 1 TatD related DNase Ribonuc_red_lgC PF02867.15 KKF92437.1 - 1.1e-192 641.3 0.0 1.4e-192 640.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KKF92437.1 - 9.4e-24 83.2 0.0 5.4e-23 80.8 0.0 2.2 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KKF92437.1 - 1.2e-17 64.2 0.0 2.5e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain Nucleo_P87 PF07267.11 KKF92437.1 - 0.037 12.9 1.2 0.056 12.3 1.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Myc_target_1 PF15179.6 KKF92437.1 - 0.076 12.9 3.5 0.14 12.1 3.5 1.3 1 0 0 1 1 1 0 Myc target protein 1 zf-CCHC PF00098.23 KKF92438.1 - 1.4e-06 28.1 2.2 3.6e-06 26.8 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KKF92438.1 - 0.043 13.6 2.1 0.11 12.3 2.1 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger Retrotran_gag_2 PF14223.6 KKF92440.1 - 2.3e-06 27.3 2.2 1.7e-05 24.5 2.2 2.0 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KKF92440.1 - 0.00038 20.4 1.5 0.00038 20.4 1.5 1.7 2 0 0 2 2 2 1 Zinc knuckle SCAN PF02023.17 KKF92440.1 - 0.011 15.5 2.0 0.023 14.5 1.3 2.0 1 1 1 2 2 2 0 SCAN domain zf-C2HE PF16278.5 KKF92440.1 - 0.068 13.6 2.6 0.15 12.5 2.0 1.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CCHC_4 PF14392.6 KKF92440.1 - 0.093 12.5 2.3 0.9 9.3 0.7 2.7 3 0 0 3 3 3 0 Zinc knuckle zf-C2H2_10 PF16588.5 KKF92440.1 - 0.12 12.2 4.8 0.2 11.4 4.8 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger DPPIV_N PF00930.21 KKF92441.1 - 4.5e-108 361.2 0.3 5.9e-108 360.8 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KKF92441.1 - 3.6e-54 183.5 0.6 7.7e-54 182.4 0.6 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KKF92441.1 - 0.0036 17.2 4.9 0.98 9.4 0.2 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DLH PF01738.18 KKF92441.1 - 0.013 15.0 0.0 0.15 11.6 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family Glyco_hydro_18 PF00704.28 KKF92442.1 - 5.1e-81 272.8 5.4 6e-81 272.6 5.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mo25 PF08569.11 KKF92443.1 - 2.2e-90 303.3 3.0 3.5e-87 292.8 2.0 2.0 1 1 1 2 2 2 2 Mo25-like NPP1 PF05630.11 KKF92444.1 - 2.5e-56 190.9 0.0 2.9e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) SWIB PF02201.18 KKF92445.1 - 4.6e-16 58.5 0.0 9.8e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DDHD PF02862.17 KKF92445.1 - 0.02 15.1 0.5 0.12 12.5 0.4 2.0 2 0 0 2 2 2 0 DDHD domain Cas_Cas1 PF01867.16 KKF92445.1 - 0.25 10.4 1.3 0.41 9.7 1.3 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas1 DUF4407 PF14362.6 KKF92445.1 - 2.7 7.3 10.6 4.7 6.5 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 KKF92446.1 - 8e-44 150.0 0.2 7.4e-43 146.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92446.1 - 8.5e-23 80.9 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF92446.1 - 0.0011 18.4 0.2 0.17 11.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KKF92446.1 - 0.0015 17.5 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KKF92446.1 - 0.0021 17.7 0.1 2.4 7.7 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KKF92446.1 - 0.0028 17.0 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKF92446.1 - 0.0073 16.3 0.2 0.014 15.3 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family bZIP_2 PF07716.15 KKF92447.1 - 5.5e-12 45.6 12.8 9.7e-12 44.8 12.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Shugoshin_N PF07558.11 KKF92447.1 - 0.00012 21.8 1.1 0.00026 20.8 1.1 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region XhlA PF10779.9 KKF92447.1 - 0.004 17.3 3.8 0.0083 16.3 3.8 1.5 1 0 0 1 1 1 1 Haemolysin XhlA TSC22 PF01166.18 KKF92447.1 - 0.014 15.7 1.3 0.014 15.7 1.3 1.9 2 0 0 2 2 1 0 TSC-22/dip/bun family Phlebovirus_NSM PF07246.11 KKF92447.1 - 0.041 13.3 2.9 0.049 13.0 2.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M LCD1 PF09798.9 KKF92447.1 - 0.079 11.5 3.9 0.082 11.4 3.9 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein CREPT PF16566.5 KKF92447.1 - 0.12 12.6 6.9 0.18 11.9 6.7 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Uds1 PF15456.6 KKF92447.1 - 0.13 12.4 9.3 0.27 11.4 9.3 1.4 1 0 0 1 1 1 0 Up-regulated During Septation bZIP_Maf PF03131.17 KKF92447.1 - 0.15 12.6 8.0 0.28 11.7 8.0 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor GIT_CC PF16559.5 KKF92447.1 - 0.17 11.8 2.9 0.36 10.7 2.9 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TssO PF17561.2 KKF92447.1 - 0.26 11.4 3.8 0.47 10.6 3.7 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssO bZIP_1 PF00170.21 KKF92447.1 - 0.32 11.1 16.7 0.36 11.0 13.9 2.1 1 1 1 2 2 2 0 bZIP transcription factor FUSC PF04632.12 KKF92447.1 - 0.32 9.5 0.6 0.37 9.3 0.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 KKF92447.1 - 0.44 10.7 4.8 0.68 10.1 4.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 KKF92447.1 - 2.4 8.8 8.4 1.6 9.4 5.4 1.9 1 1 1 2 2 2 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 KKF92447.1 - 2.5 8.4 13.5 7 6.9 9.3 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mt_ATP-synt_D PF05873.12 KKF92448.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Ppx-GppA PF02541.16 KKF92449.1 - 2.3e-25 89.6 0.0 3.5e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family TctC PF03401.14 KKF92449.1 - 0.081 12.0 0.0 0.34 9.9 0.0 1.9 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter family receptor BTB PF00651.31 KKF92450.1 - 0.079 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain RAP1 PF07218.11 KKF92450.1 - 7.9 4.6 4.8 15 3.7 4.8 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_transf_20 PF00982.21 KKF92451.1 - 4.2e-147 490.7 0.3 6.3e-145 483.5 0.3 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KKF92451.1 - 5.8e-44 150.0 0.0 1e-43 149.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase DDR PF08841.10 KKF92451.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Glyco_transf_5 PF08323.11 KKF92451.1 - 0.13 11.9 0.7 0.24 11.1 0.7 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain INSIG PF07281.12 KKF92452.1 - 1.9e-21 76.7 0.0 2.6e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) LapA_dom PF06305.11 KKF92452.1 - 1 9.2 2.7 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain But2 PF09792.9 KKF92453.1 - 0.00019 21.8 0.3 0.081 13.3 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin 3 binding protein But2 C-terminal domain Glyco_hydro_17 PF00332.18 KKF92454.1 - 1.3e-35 123.5 1.3 1e-34 120.6 1.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Asp PF00026.23 KKF92455.1 - 7.1e-29 101.2 4.3 9.3e-29 100.8 4.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKF92455.1 - 9e-16 58.6 0.3 1.8e-15 57.6 0.3 1.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KKF92455.1 - 0.00065 20.2 0.1 0.0044 17.5 0.1 2.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KKF92455.1 - 0.0013 19.3 0.0 0.0054 17.4 0.0 2.1 1 1 0 1 1 1 1 Aspartyl protease S1-P1_nuclease PF02265.16 KKF92456.1 - 2.5e-65 220.8 0.0 2.9e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Nuc_sug_transp PF04142.15 KKF92458.1 - 3.4e-91 305.7 9.8 5.5e-91 305.0 9.8 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KKF92458.1 - 1.7e-05 24.2 12.7 0.00015 21.1 12.2 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KKF92458.1 - 2e-05 24.8 30.3 0.00025 21.2 7.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KKF92458.1 - 0.011 14.7 10.1 0.24 10.3 2.7 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KKF92458.1 - 0.012 15.0 2.0 0.012 15.0 2.0 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family NTP_transferase PF00483.23 KKF92459.1 - 2.7e-30 105.8 0.0 4.2e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KKF92459.1 - 1.4e-08 34.1 7.5 3.6e-06 26.5 0.1 3.4 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KKF92459.1 - 2e-07 31.5 0.0 3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KKF92459.1 - 0.018 14.8 1.8 0.24 11.2 0.0 3.1 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Glycos_transf_2 PF00535.26 KKF92459.1 - 0.032 14.0 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF4954 PF16314.5 KKF92459.1 - 0.14 10.2 0.1 0.22 9.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Dynamin_N PF00350.23 KKF92460.1 - 9.3e-19 68.1 0.2 5e-18 65.7 0.0 2.4 3 1 0 3 3 3 1 Dynamin family Dynamin_M PF01031.20 KKF92460.1 - 9.5e-07 28.3 1.4 1.7e-06 27.5 0.1 2.0 3 0 0 3 3 3 1 Dynamin central region GED PF02212.18 KKF92460.1 - 0.0015 18.6 0.4 0.0067 16.5 0.4 2.2 1 1 0 1 1 1 1 Dynamin GTPase effector domain ABC_tran PF00005.27 KKF92460.1 - 0.013 16.0 0.1 0.086 13.4 0.0 2.4 3 0 0 3 3 3 0 ABC transporter Roc PF08477.13 KKF92460.1 - 0.19 11.9 0.7 1.4 9.1 0.0 2.7 3 1 1 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Cytochrom_B562 PF07361.11 KKF92460.1 - 0.22 12.2 4.4 5.4 7.7 0.1 3.1 3 0 0 3 3 3 0 Cytochrome b562 DUF2922 PF11148.8 KKF92461.1 - 0.057 13.1 0.3 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) WD40 PF00400.32 KKF92462.1 - 3.3e-118 382.2 55.3 1.2e-10 41.8 0.1 14.2 14 0 0 14 14 14 13 WD domain, G-beta repeat NACHT_N PF17100.5 KKF92462.1 - 6.3e-64 215.8 1.0 6.3e-64 215.8 1.0 1.8 2 0 0 2 2 1 1 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 KKF92462.1 - 6.4e-50 167.4 22.0 0.00017 21.8 0.2 11.6 1 1 10 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KKF92462.1 - 3.5e-17 62.8 0.0 7.7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KKF92462.1 - 4.8e-16 58.6 25.9 7.8e-05 21.8 0.9 9.1 1 1 7 8 8 8 7 WD40 region of Ge1, enhancer of mRNA-decapping protein Robl_LC7 PF03259.17 KKF92462.1 - 3.9e-09 36.1 4.9 2.9 7.7 0.0 8.3 3 2 5 8 8 8 2 Roadblock/LC7 domain PD40 PF07676.12 KKF92462.1 - 1.3e-07 31.4 0.0 1.3e+02 2.6 0.0 8.7 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KKF92462.1 - 4.9e-05 22.0 10.7 0.033 12.7 0.1 4.9 1 1 3 5 5 5 4 Cytochrome D1 heme domain TsaE PF02367.17 KKF92462.1 - 0.0046 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Nucleoporin_N PF08801.11 KKF92462.1 - 0.29 9.8 5.5 1.3 7.7 0.5 3.6 2 2 2 4 4 4 0 Nup133 N terminal like DUF5559 PF17714.1 KKF92462.1 - 0.88 9.4 5.3 51 3.7 0.0 4.4 5 0 0 5 5 5 0 Family of unknown function (DUF5559) LCAT PF02450.15 KKF92463.1 - 3.5e-97 326.0 0.1 4.4e-97 325.7 0.1 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KKF92463.1 - 0.015 15.9 0.1 0.03 14.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family IMS PF00817.20 KKF92465.1 - 8.1e-41 139.5 0.0 1.2e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KKF92465.1 - 1.1e-09 39.0 0.0 3.4e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KKF92465.1 - 0.012 15.9 0.1 0.029 14.7 0.1 1.6 1 0 0 1 1 1 0 IMS family HHH motif WD40 PF00400.32 KKF92466.1 - 1.7e-75 247.0 30.1 4.5e-11 43.1 0.1 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat NACHT_N PF17100.5 KKF92466.1 - 1.4e-44 152.6 0.2 3e-44 151.5 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 KKF92466.1 - 1.6e-30 105.3 6.5 0.00019 21.7 0.2 7.4 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KKF92466.1 - 1.1e-18 67.7 0.1 2.6e-18 66.5 0.0 1.7 2 0 0 2 2 2 1 NACHT domain Ge1_WD40 PF16529.5 KKF92466.1 - 1.6e-09 37.2 17.0 0.0015 17.6 1.9 5.4 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KKF92466.1 - 2.9e-06 26.2 14.0 2.2 6.8 0.1 6.5 1 1 6 7 7 7 4 Nucleoporin Nup120/160 BLUF PF04940.12 KKF92466.1 - 0.00085 19.4 0.0 88 3.3 0.0 5.4 5 1 1 6 6 5 0 Sensors of blue-light using FAD TsaE PF02367.17 KKF92466.1 - 0.00096 19.2 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KKF92466.1 - 0.002 17.4 0.2 2.1 7.4 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Me-amine-dh_H PF06433.11 KKF92466.1 - 0.003 16.5 0.1 3.7 6.3 0.0 3.4 1 1 3 4 4 4 1 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.16 KKF92466.1 - 0.019 13.5 1.3 1.5 7.2 0.1 3.1 1 1 1 3 3 3 0 Cytochrome D1 heme domain Big_7 PF17957.1 KKF92466.1 - 0.053 14.3 9.2 32 5.4 0.3 5.7 5 1 1 6 6 6 0 Bacterial Ig domain Trp_oprn_chp PF09534.10 KKF92470.1 - 0.0025 17.7 1.0 0.0029 17.4 1.0 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gram_pos_anchor PF00746.21 KKF92470.1 - 0.0033 17.3 1.9 0.0033 17.3 1.9 2.7 2 2 1 3 3 3 1 LPXTG cell wall anchor motif MGC-24 PF05283.11 KKF92470.1 - 0.005 17.3 1.1 0.0074 16.7 1.1 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Nitrate_red_gam PF02665.14 KKF92470.1 - 0.0055 16.3 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 Nitrate reductase gamma subunit Mucin PF01456.17 KKF92470.1 - 0.0073 16.3 8.9 0.011 15.8 8.9 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF4366 PF14283.6 KKF92470.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) BatD PF13584.6 KKF92470.1 - 0.016 14.0 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF5305 PF17231.2 KKF92470.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Phage_HK97_TLTM PF06120.11 KKF92470.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Tail length tape measure protein Podoplanin PF05808.11 KKF92470.1 - 0.037 14.1 0.3 0.054 13.6 0.3 1.2 1 0 0 1 1 1 0 Podoplanin Alpha_GJ PF03229.13 KKF92470.1 - 0.33 11.5 14.3 0.59 10.7 14.3 1.4 1 1 0 1 1 1 0 Alphavirus glycoprotein J FSA_C PF10479.9 KKF92470.1 - 5.9 4.9 7.3 7.4 4.6 7.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus VID27 PF08553.10 KKF92471.1 - 1.1e-191 636.6 0.0 1.5e-191 636.0 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KKF92471.1 - 2e-70 236.2 1.4 2e-70 236.2 1.4 2.6 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 KKF92471.1 - 2.4e-41 140.4 1.4 6.8e-41 139.0 1.4 1.9 1 0 0 1 1 1 1 VID27 PH-like domain Prenylcys_lyase PF07156.14 KKF92471.1 - 8e-37 127.2 0.0 1.7e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KKF92471.1 - 2.2e-12 47.0 0.0 4.9e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KKF92471.1 - 1.8e-07 30.8 0.0 4.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KKF92471.1 - 3e-05 23.8 0.1 0.00013 21.7 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKF92471.1 - 0.0064 15.8 0.3 0.037 13.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKF92471.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF2052 PF09747.9 KKF92471.1 - 3 7.9 22.0 1.7 8.8 8.6 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Aldose_epim PF01263.20 KKF92472.1 - 3.1e-28 99.0 0.2 3.6e-28 98.7 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase GREB1 PF15782.5 KKF92473.1 - 1.3 6.1 16.0 2.2 5.3 16.0 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIF_alpha PF05793.12 KKF92473.1 - 2.8 6.4 60.3 0.088 11.4 23.9 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glyco_transf_20 PF00982.21 KKF92474.1 - 4.4e-195 648.9 0.0 5.1e-195 648.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 KKF92474.1 - 0.00056 20.4 0.0 0.0012 19.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KKF92474.1 - 0.038 13.7 0.1 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KKF92474.1 - 0.039 13.5 0.2 1.8 8.1 0.0 2.6 2 1 0 2 2 2 0 Glycosyl transferases group 1 Amino_oxidase PF01593.24 KKF92476.1 - 1.4e-57 196.0 0.0 1.8e-57 195.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKF92476.1 - 6.9e-09 35.8 0.1 6.3e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKF92476.1 - 0.04 13.5 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKF92476.1 - 0.057 12.6 0.0 0.77 8.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DASH_Dad4 PF08650.10 KKF92476.1 - 0.5 10.4 3.2 9.5 6.3 0.0 3.5 5 0 0 5 5 5 0 DASH complex subunit Dad4 RhgB_N PF09284.10 KKF92477.1 - 2.9e-97 325.1 1.4 2.9e-97 325.1 1.4 1.4 2 0 0 2 2 2 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KKF92477.1 - 1.6e-33 115.9 0.0 4.6e-33 114.4 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KKF92477.1 - 3.2e-20 71.7 2.3 3.2e-20 71.7 2.3 2.4 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KKF92477.1 - 0.00041 20.6 0.3 0.00041 20.6 0.3 3.1 5 0 0 5 5 5 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 KKF92477.1 - 0.008 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 KKF92477.1 - 0.039 13.9 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 CarboxypepD_reg-like domain GCIP PF13324.6 KKF92478.1 - 4.4e-07 29.8 5.2 7.4e-07 29.0 4.9 1.6 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Lant_dehydr_N PF04738.13 KKF92478.1 - 0.082 11.0 0.7 4.9 5.1 0.6 2.1 2 0 0 2 2 2 0 Lantibiotic dehydratase, N terminus Patatin PF01734.22 KKF92479.1 - 0.00055 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DIT1_PvcA PF05141.12 KKF92479.1 - 0.094 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Retrotrans_gag PF03732.17 KKF92480.1 - 0.0016 18.7 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein FMN_red PF03358.15 KKF92481.1 - 1.4e-25 89.9 0.0 1.7e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KKF92481.1 - 0.0028 17.4 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold preATP-grasp_3 PF18301.1 KKF92481.1 - 0.047 14.0 0.0 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 pre ATP-grasp 3 domain Retrotrans_gag PF03732.17 KKF92482.1 - 0.0029 17.8 0.0 0.0082 16.4 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 KKF92482.1 - 0.0071 16.4 5.4 0.012 15.7 5.4 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 KKF92482.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Preseq_ALAS PF09029.10 KKF92482.1 - 0.13 12.7 0.3 0.28 11.7 0.3 1.5 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence zf-CCHC_6 PF15288.6 KKF92482.1 - 0.35 10.7 3.7 0.74 9.7 3.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KKF92482.1 - 1 9.3 3.9 1.7 8.6 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle FAT PF02259.23 KKF92485.1 - 1.4e-123 412.5 5.3 1.4e-123 412.5 5.3 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KKF92485.1 - 7.7e-74 248.7 0.1 1.3e-73 247.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KKF92485.1 - 1.8e-69 232.7 5.9 5.2e-67 224.8 0.2 5.7 6 1 1 7 7 7 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KKF92485.1 - 2e-43 146.8 2.7 2.8e-43 146.3 0.1 2.8 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 KKF92485.1 - 1.2e-14 54.5 8.7 0.00024 21.4 0.0 8.6 8 0 0 8 8 7 2 HEAT repeats FATC PF02260.20 KKF92485.1 - 1.2e-12 47.4 0.1 4.8e-12 45.5 0.1 2.1 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KKF92485.1 - 3.9e-12 45.3 26.7 0.0011 19.0 0.0 11.3 13 0 0 13 13 13 5 HEAT repeat HEAT_EZ PF13513.6 KKF92485.1 - 5.1e-11 42.8 25.6 2.8e-05 24.5 0.1 12.2 12 2 2 14 14 13 2 HEAT-like repeat Cnd1 PF12717.7 KKF92485.1 - 3.4e-05 24.0 5.3 0.089 12.8 0.4 5.4 4 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.8 KKF92485.1 - 0.095 12.3 2.5 1.8 8.1 0.1 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF3730) RNase_T PF00929.24 KKF92485.1 - 0.12 12.9 0.0 2.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Exonuclease Sec7_N PF12783.7 KKF92485.1 - 0.35 10.8 4.1 33 4.3 0.0 4.7 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal MMS19_C PF12460.8 KKF92485.1 - 0.83 8.7 5.9 0.93 8.5 0.3 3.4 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal ANAPC3 PF12895.7 KKF92485.1 - 2.6 8.3 6.4 6.6 7.0 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PRKCSH-like PF12999.7 KKF92486.1 - 7.9e-44 149.5 2.0 1.7e-27 96.3 0.1 2.8 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KKF92486.1 - 1.2e-30 106.2 1.1 1.2e-30 106.2 1.1 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KKF92486.1 - 7.2e-10 39.7 2.7 2.2e-09 38.2 2.7 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KKF92486.1 - 0.0018 18.2 1.3 0.0035 17.2 1.3 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 Fib_alpha PF08702.10 KKF92486.1 - 0.12 12.6 4.3 1.2 9.3 0.7 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KKF92486.1 - 1.1 8.5 14.5 0.77 9.1 11.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1690 PF07956.11 KKF92486.1 - 1.8 9.0 8.1 4.3 7.8 8.1 1.7 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Mod_r PF07200.13 KKF92486.1 - 1.9 8.6 14.8 0.2 11.7 0.3 2.9 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Lebercilin PF15619.6 KKF92486.1 - 2.8 7.5 18.0 0.14 11.8 12.1 1.8 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CENP-H PF05837.12 KKF92486.1 - 3.3 8.2 15.4 2.7 8.4 8.7 3.3 4 0 0 4 4 4 0 Centromere protein H (CENP-H) cobW PF02492.19 KKF92487.1 - 1.7e-33 115.7 0.0 2e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KKF92487.1 - 0.00073 18.6 1.2 0.028 13.4 1.2 2.1 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KKF92487.1 - 0.0014 18.7 0.0 0.0032 17.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 KKF92487.1 - 0.024 14.7 0.0 0.04 14.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KKF92487.1 - 0.043 14.2 0.0 0.066 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KKF92487.1 - 0.049 13.6 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KKF92487.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KKF92487.1 - 0.051 13.6 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KKF92487.1 - 0.052 12.7 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 KKF92487.1 - 0.075 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 KKF92487.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein PRK PF00485.18 KKF92487.1 - 0.086 12.6 0.1 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 KKF92487.1 - 0.094 13.2 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KKF92487.1 - 0.16 12.4 0.0 0.48 10.9 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KKF92487.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KKF92487.1 - 0.22 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RIBIOP_C PF04950.12 KKF92488.1 - 5.4e-107 357.6 0.0 1.1e-106 356.5 0.0 1.6 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KKF92488.1 - 9.8e-17 60.8 0.0 2.8e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BING4CT PF08149.11 KKF92489.1 - 9.4e-38 127.9 0.0 3.2e-35 119.8 0.0 3.4 3 0 0 3 3 3 1 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KKF92489.1 - 8.1e-06 26.1 1.4 4.7 7.6 0.0 5.7 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKF92489.1 - 0.0013 19.5 0.3 3.1 8.8 0.0 4.5 4 1 1 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KKF92489.1 - 0.05 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region MAP65_ASE1 PF03999.12 KKF92489.1 - 0.21 10.2 9.0 0.029 13.1 4.8 1.6 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Activator_LAG-3 PF11498.8 KKF92489.1 - 0.33 9.9 4.2 0.5 9.3 4.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 NACHT PF05729.12 KKF92490.1 - 5.7e-22 78.4 0.0 2.3e-21 76.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Patatin PF01734.22 KKF92490.1 - 6.2e-14 52.7 0.3 3.5e-08 33.9 0.2 2.6 1 1 1 2 2 2 2 Patatin-like phospholipase AAA_16 PF13191.6 KKF92490.1 - 0.00021 21.7 0.0 0.0018 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KKF92490.1 - 0.00043 20.6 0.0 0.0018 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKF92490.1 - 0.016 15.5 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKF92490.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KKF92490.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_pol_Rpb4 PF03874.16 KKF92490.1 - 2 8.7 6.6 0.69 10.2 0.5 3.2 2 2 0 2 2 2 0 RNA polymerase Rpb4 MFS_1 PF07690.16 KKF92492.1 - 6.5e-38 130.6 17.2 8.4e-38 130.2 17.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKF92492.1 - 1.6e-06 27.3 12.9 5e-06 25.7 12.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KKF92492.1 - 0.001 17.6 2.3 0.0016 17.0 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KKF92492.1 - 0.0064 15.4 3.1 0.021 13.7 1.5 2.6 2 1 0 2 2 2 1 MFS_1 like family DUF5588 PF17826.1 KKF92492.1 - 0.031 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5588) Kinesin PF00225.23 KKF92493.1 - 2.5e-97 325.8 0.0 2.5e-97 325.8 0.0 2.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KKF92493.1 - 4.8e-23 81.7 0.0 2.7e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 KKF92493.1 - 0.02 14.7 0.7 0.02 14.7 0.7 4.3 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Y_Y_Y PF07495.13 KKF92493.1 - 0.04 13.9 0.2 0.095 12.7 0.2 1.6 1 0 0 1 1 1 0 Y_Y_Y domain Tho2 PF11262.8 KKF92493.1 - 0.89 8.7 2.5 1.6 7.8 2.5 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 KKF92493.1 - 0.9 8.8 11.7 2.2 7.5 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Com_YlbF PF06133.11 KKF92493.1 - 1.1 9.9 5.7 0.98 10.1 3.9 1.8 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Sulfate_transp PF00916.20 KKF92494.1 - 1e-51 175.9 12.8 1e-51 175.9 12.8 1.6 2 0 0 2 2 2 1 Sulfate permease family Stk19 PF10494.9 KKF92494.1 - 3.7e-42 144.7 0.0 5.3e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 cNMP_binding PF00027.29 KKF92494.1 - 1.8e-16 60.0 0.0 1.3e-14 54.0 0.0 2.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain STAS PF01740.21 KKF92494.1 - 6.4e-12 45.1 0.1 1.7e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 STAS domain DUF2613 PF11021.8 KKF92494.1 - 2.8 8.1 6.6 3.9 7.6 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Sld5 PF05916.11 KKF92495.1 - 1.3e-09 38.5 0.0 1.8e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein ArAE_1_C PF11728.8 KKF92495.1 - 0.037 14.0 1.2 3.4 7.6 0.1 2.4 3 0 0 3 3 3 0 Putative aromatic acid exporter C-terminal domain ATP-synt_10 PF05176.14 KKF92496.1 - 4.5e-71 239.1 0.0 8.1e-71 238.3 0.0 1.4 1 0 0 1 1 1 1 ATP10 protein Ribosomal_L29 PF00831.23 KKF92496.1 - 2.8e-15 56.0 1.4 2.8e-15 56.0 1.4 2.5 2 0 0 2 2 2 1 Ribosomal L29 protein 2-oxoacid_dh PF00198.23 KKF92497.1 - 3.2e-75 252.6 0.0 6.8e-75 251.5 0.0 1.5 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KKF92497.1 - 5.7e-18 64.5 0.1 1.2e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KKF92497.1 - 6.2e-14 52.1 0.1 1.5e-13 50.8 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain HlyD_D23 PF16576.5 KKF92497.1 - 0.00022 20.5 0.4 0.00036 19.8 0.4 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 KKF92497.1 - 0.047 13.5 2.1 0.072 12.9 0.1 2.4 3 0 0 3 3 3 0 Biotin-lipoyl like SKI PF01202.22 KKF92498.1 - 1e-11 45.2 0.0 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KKF92498.1 - 1.4e-09 38.6 0.0 5.6e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKF92498.1 - 7.6e-08 32.6 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KKF92498.1 - 1.9e-06 28.4 0.0 4.8e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KKF92498.1 - 2.6e-05 24.1 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Rad17 PF03215.15 KKF92498.1 - 4.5e-05 23.4 0.0 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KKF92498.1 - 0.0015 19.0 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 KKF92498.1 - 0.0016 18.3 0.0 0.063 13.1 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_5 PF07728.14 KKF92498.1 - 0.0024 17.9 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KKF92498.1 - 0.005 17.1 0.0 0.0078 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKF92498.1 - 0.0057 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KKF92498.1 - 0.0079 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA PF00004.29 KKF92498.1 - 0.011 16.2 0.0 0.016 15.7 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KKF92498.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CoaE PF01121.20 KKF92498.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase PRK PF00485.18 KKF92498.1 - 0.028 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 KKF92498.1 - 0.029 14.1 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KKF92498.1 - 0.045 13.0 0.0 0.07 12.4 0.0 1.3 1 1 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 KKF92498.1 - 0.047 13.1 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ploopntkinase1 PF18748.1 KKF92498.1 - 0.053 13.0 0.0 0.74 9.3 0.0 2.2 2 1 0 2 2 2 0 P-loop Nucleotide Kinase1 DNA_pol3_delta2 PF13177.6 KKF92498.1 - 0.054 13.3 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NACHT PF05729.12 KKF92498.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KKF92498.1 - 0.093 13.2 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Herpes_Helicase PF02689.14 KKF92498.1 - 0.12 10.3 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 Helicase Thymidylate_kin PF02223.17 KKF92498.1 - 0.13 12.0 0.0 6.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_14 PF13173.6 KKF92498.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 KKF92498.1 - 0.16 12.0 0.0 0.48 10.5 0.0 1.9 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_30 PF13604.6 KKF92498.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKF92498.1 - 0.2 11.6 0.0 0.55 10.1 0.0 1.7 2 0 0 2 2 2 0 NTPase DUF3535 PF12054.8 KKF92499.1 - 6.3e-116 388.2 0.4 3.2e-115 385.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KKF92499.1 - 1.5e-63 214.7 0.0 4.1e-63 213.2 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKF92499.1 - 6.7e-19 68.3 0.0 2e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KKF92499.1 - 8.3e-19 66.1 5.0 0.36 11.2 0.0 8.9 9 0 0 9 9 9 6 HEAT repeat HEAT_2 PF13646.6 KKF92499.1 - 8.2e-08 32.5 8.3 0.0093 16.3 0.1 6.8 6 0 0 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KKF92499.1 - 3.8e-07 30.6 0.3 0.067 13.8 0.0 4.1 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KKF92499.1 - 0.0038 17.7 11.5 9.5 6.8 0.1 7.5 8 0 0 8 8 8 1 HEAT-like repeat CLASP_N PF12348.8 KKF92499.1 - 0.028 14.0 0.3 1.8 8.1 0.0 3.1 3 0 0 3 3 3 0 CLASP N terminal IFRD PF05004.13 KKF92499.1 - 0.088 11.9 2.2 1.6 7.7 0.0 3.4 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) UME PF08064.13 KKF92499.1 - 0.43 10.5 2.5 20 5.2 0.0 3.8 4 0 0 4 4 4 0 UME (NUC010) domain CDC37_N PF03234.14 KKF92500.1 - 2.1e-44 151.6 0.4 2.1e-44 151.6 0.4 3.9 3 1 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KKF92500.1 - 6.7e-36 122.8 0.0 2.7e-35 120.9 0.0 2.1 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KKF92500.1 - 5.2e-30 103.5 10.8 1.3e-29 102.3 3.5 2.6 2 0 0 2 2 2 2 Cdc37 C terminal domain DUF4407 PF14362.6 KKF92500.1 - 2.4 7.4 15.4 1 8.6 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Choline_transpo PF04515.12 KKF92501.1 - 1.9e-80 270.5 21.9 1.9e-80 270.5 21.9 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter MgtC PF02308.16 KKF92501.1 - 0.016 15.5 2.6 0.016 15.5 2.6 4.4 3 3 2 5 5 5 0 MgtC family Mre11_DNA_bind PF04152.14 KKF92503.1 - 2e-51 174.7 2.3 2.2e-51 174.5 1.0 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KKF92503.1 - 4.6e-15 56.7 0.9 8.6e-15 55.8 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MS_channel PF00924.18 KKF92504.1 - 1.6e-19 70.3 0.8 2.7e-19 69.5 0.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KKF92504.1 - 0.00056 19.3 0.7 0.0021 17.5 0.7 2.0 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KKF92504.1 - 0.0015 17.9 1.4 0.0049 16.3 0.4 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KKF92504.1 - 0.0049 16.7 3.1 0.0082 16.0 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KKF92504.1 - 0.02 15.3 0.2 0.36 11.3 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair DLH PF01738.18 KKF92505.1 - 1.3e-25 90.2 0.0 1.7e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KKF92505.1 - 0.002 18.8 0.3 0.0027 18.3 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KKF92505.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.6 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Histone PF00125.24 KKF92506.1 - 1.7e-17 64.0 0.0 2.4e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KKF92506.1 - 1.7e-13 50.1 0.1 1.7e-13 50.1 0.1 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KKF92506.1 - 6.1e-05 23.2 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.22 KKF92507.1 - 4.3e-11 42.6 0.1 8.9e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KKF92507.1 - 4.4e-07 29.6 0.0 7.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KKF92507.1 - 0.064 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 RRM_2 PF04059.12 KKF92507.1 - 0.18 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Abp2 PF09441.10 KKF92508.1 - 1e-82 276.3 0.0 1.7e-82 275.6 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 Sds3 PF08598.11 KKF92510.1 - 4.2e-12 46.5 21.0 6.9e-12 45.8 20.7 1.6 1 1 0 1 1 1 1 Sds3-like DUF743 PF05332.11 KKF92510.1 - 0.039 14.0 0.4 0.097 12.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF743) DUF2433 PF10360.9 KKF92510.1 - 0.18 11.9 2.0 7.2 6.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) UPF0270 PF06794.12 KKF92511.1 - 0.027 14.5 0.1 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Ist1 PF03398.14 KKF92511.1 - 0.11 12.4 0.6 0.24 11.3 0.6 1.6 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PAF-AH_p_II PF03403.13 KKF92514.1 - 8e-15 54.2 0.0 1.3e-13 50.3 0.0 2.1 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Haem_bd PF14376.6 KKF92514.1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Haem-binding domain EXS PF03124.14 KKF92515.1 - 6.2e-99 331.4 27.2 8e-99 331.1 27.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KKF92515.1 - 3e-79 267.7 9.7 3e-79 267.7 9.7 1.5 2 0 0 2 2 2 1 SPX domain PBP1_TM PF14812.6 KKF92515.1 - 7.3 7.0 9.1 10 6.6 4.0 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_M18 PF02127.15 KKF92516.1 - 1.8e-121 406.0 0.0 2.1e-121 405.7 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) 3HCDH_RFF PF18321.1 KKF92516.1 - 0.15 12.5 0.1 0.33 11.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain AAA PF00004.29 KKF92517.1 - 2.4e-41 141.2 0.0 4.5e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKF92517.1 - 1.1e-11 44.5 0.2 2.4e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KKF92517.1 - 2.9e-10 39.8 0.4 5.5e-10 38.9 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KKF92517.1 - 2.8e-06 27.7 0.2 0.0049 17.1 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KKF92517.1 - 4.3e-06 26.9 0.0 8.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KKF92517.1 - 1.4e-05 24.4 0.0 2.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KKF92517.1 - 2.4e-05 24.4 0.0 8.1e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKF92517.1 - 0.00019 21.8 0.2 0.0018 18.7 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain Prot_ATP_OB_N PF17758.1 KKF92517.1 - 0.00037 20.1 0.7 0.0034 17.0 0.0 2.5 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain RuvB_N PF05496.12 KKF92517.1 - 0.00046 20.0 0.0 0.00094 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KKF92517.1 - 0.0019 18.4 0.1 0.0073 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KKF92517.1 - 0.0086 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKF92517.1 - 0.0089 16.6 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKF92517.1 - 0.012 15.8 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KKF92517.1 - 0.015 14.6 0.1 0.5 9.7 0.1 2.4 1 1 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 KKF92517.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 KKF92517.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KKF92517.1 - 0.022 14.0 0.1 0.054 12.7 0.1 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 KKF92517.1 - 0.045 13.7 0.3 0.62 10.0 0.1 2.6 2 1 1 3 3 3 0 NACHT domain Zeta_toxin PF06414.12 KKF92517.1 - 0.046 13.0 0.0 0.18 11.1 0.0 1.9 3 0 0 3 3 3 0 Zeta toxin Mg_chelatase PF01078.21 KKF92517.1 - 0.051 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KKF92517.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 KKF92517.1 - 0.067 12.6 1.0 0.5 9.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KKF92517.1 - 0.1 12.3 1.6 0.26 11.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KKF92517.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KKF92517.1 - 0.12 12.0 2.6 0.52 9.9 0.4 2.6 2 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KKF92517.1 - 0.15 12.6 0.4 0.89 10.1 0.4 2.4 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KKF92517.1 - 0.18 11.3 0.1 0.5 9.9 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region UQ_con PF00179.26 KKF92518.1 - 1.5e-40 138.1 0.0 1.9e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKF92518.1 - 2.7e-07 30.4 0.0 4.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_3 PF09288.10 KKF92518.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UEV PF05743.13 KKF92518.1 - 0.017 14.9 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 UEV domain HetR_C PF18460.1 KKF92518.1 - 0.16 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain Ligase_CoA PF00549.19 KKF92519.1 - 2.9e-23 82.4 0.6 4.6e-23 81.7 0.6 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KKF92519.1 - 4.2e-23 81.8 2.6 9.2e-21 74.3 0.2 3.2 3 0 0 3 3 3 1 CoA binding domain Succ_CoA_lig PF13607.6 KKF92519.1 - 3e-09 36.8 0.1 5.2e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKF92519.1 - 0.00034 21.1 0.0 0.00085 19.8 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Bd3614-deam PF14439.6 KKF92519.1 - 0.12 12.5 0.4 0.24 11.5 0.1 1.6 2 0 0 2 2 2 0 Bd3614-like deaminase Radical_SAM_C PF16199.5 KKF92520.1 - 4.8e-32 109.8 0.0 1.8e-31 108.0 0.0 2.0 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KKF92520.1 - 6.5e-18 65.7 0.1 2.8e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KKF92520.1 - 3.7e-09 36.9 0.1 7.6e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKF92520.1 - 6.7e-06 26.1 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKF92520.1 - 0.046 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_72 PF03198.14 KKF92521.1 - 9.2e-122 406.2 4.9 1.2e-121 405.8 4.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KKF92521.1 - 6.9e-22 77.9 3.1 2e-21 76.4 3.1 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 KKF92521.1 - 0.0087 15.2 0.9 0.075 12.1 0.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain AF-4 PF05110.13 KKF92521.1 - 8.5 4.3 9.1 11 3.9 9.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RVT_1 PF00078.27 KKF92524.1 - 1.2e-24 87.0 0.0 3.2e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KKF92524.1 - 3.9e-05 23.5 2.9 3.9e-05 23.5 2.9 1.6 2 0 0 2 2 2 1 Zinc knuckle Retrotran_gag_2 PF14223.6 KKF92524.1 - 0.00052 19.7 0.0 0.0017 18.0 0.0 1.9 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Ste5_C PF12194.8 KKF92524.1 - 0.4 10.6 2.1 26 4.7 0.1 2.8 3 1 0 3 3 3 0 Protein kinase Fus3-binding MFS_1 PF07690.16 KKF92525.1 - 3.9e-14 52.4 41.5 3.5e-13 49.2 40.1 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Mntp PF02659.15 KKF92525.1 - 7.9 6.2 15.0 4.6 7.0 2.2 3.3 4 0 0 4 4 4 0 Putative manganese efflux pump Y_phosphatase2 PF03162.13 KKF92526.1 - 7.8e-28 97.1 0.0 5.3e-13 48.9 0.0 2.1 1 1 1 2 2 2 2 Tyrosine phosphatase family CPP1-like PF11833.8 KKF92527.1 - 0.033 13.9 0.1 0.041 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF1977 PF09320.11 KKF92528.1 - 2.6e-27 95.1 0.0 5e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KKF92528.1 - 1.2e-20 73.4 0.3 2e-20 72.6 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain IRF PF00605.17 KKF92529.1 - 0.053 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor Mcp5_PH PF12814.7 KKF92530.1 - 2.9e-46 156.5 0.5 2.3e-45 153.6 0.0 2.3 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KKF92530.1 - 0.0012 19.3 18.6 0.0012 19.3 18.6 1.8 2 0 0 2 2 2 1 Fez1 TPR_MLP1_2 PF07926.12 KKF92530.1 - 0.37 10.8 26.1 0.1 12.6 15.2 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RR_TM4-6 PF06459.12 KKF92530.1 - 2.1 8.1 10.9 4.1 7.1 10.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pescadillo_N PF06732.11 KKF92531.1 - 2.8e-121 404.3 0.3 2.8e-121 404.3 0.3 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.26 KKF92531.1 - 0.00015 22.1 0.0 0.0023 18.3 0.0 2.7 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKF92531.1 - 0.001 19.4 0.4 0.015 15.7 0.4 2.6 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KKF92531.1 - 0.057 13.7 1.2 0.88 9.9 1.2 2.6 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain CNDH2_C PF16858.5 KKF92532.1 - 0.013 15.4 3.9 0.015 15.2 3.9 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Pox_Ag35 PF03286.14 KKF92532.1 - 0.037 13.8 1.7 0.045 13.5 1.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 KKF92532.1 - 0.3 11.8 8.6 0.51 11.1 8.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) BUD22 PF09073.10 KKF92532.1 - 0.33 10.2 9.2 0.39 10.0 9.2 1.1 1 0 0 1 1 1 0 BUD22 BTV_NS2 PF04514.12 KKF92532.1 - 0.37 9.6 4.0 0.45 9.3 4.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FXR_C3 PF16097.5 KKF92532.1 - 0.45 11.2 8.0 0.16 12.6 3.8 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 Pes-10 PF07149.11 KKF92532.1 - 3.9 6.4 9.5 4.8 6.1 9.5 1.1 1 0 0 1 1 1 0 Pes-10 NOA36 PF06524.12 KKF92532.1 - 7.4 5.8 9.6 11 5.3 9.6 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KKF92532.1 - 9.2 4.2 10.7 9.7 4.1 10.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Kinesin PF00225.23 KKF92533.1 - 1.5e-108 362.7 0.4 1.5e-108 362.7 0.4 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KKF92533.1 - 1.4e-26 93.3 1.1 3.1e-26 92.1 0.2 2.2 2 0 0 2 2 2 1 Microtubule binding DUF3802 PF12290.8 KKF92533.1 - 0.0085 16.6 1.0 0.072 13.6 1.0 2.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3802) Apolipoprotein PF01442.18 KKF92533.1 - 2.1 8.2 47.5 0.25 11.2 16.6 4.4 1 1 3 4 4 4 0 Apolipoprotein A1/A4/E domain ACP_PD PF04336.12 KKF92533.1 - 2.2 8.7 5.2 5.6 7.4 0.1 4.0 3 1 1 4 4 4 0 Acyl carrier protein phosphodiesterase BDV_P24 PF06595.11 KKF92533.1 - 3.3 7.5 9.0 0.39 10.6 0.3 3.5 2 1 2 4 4 4 0 Borna disease virus P24 protein UPF0183 PF03676.14 KKF92534.1 - 3.3e-60 204.4 0.0 1.3e-39 136.7 0.0 3.3 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0183) Glyco_hydro_cc PF11790.8 KKF92535.1 - 1.5e-52 178.5 0.2 2.4e-52 177.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Sdh5 PF03937.16 KKF92535.1 - 0.16 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Macoilin PF09726.9 KKF92535.1 - 1 7.8 4.6 1.4 7.4 4.6 1.1 1 0 0 1 1 1 0 Macoilin family CoA_trans PF01144.23 KKF92536.1 - 2.4e-95 318.0 1.4 1e-60 204.9 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AA_permease PF00324.21 KKF92537.1 - 4.8e-107 358.5 41.0 6.6e-107 358.1 41.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKF92537.1 - 8.4e-19 67.7 43.1 1.2e-18 67.1 43.1 1.2 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 KKF92537.1 - 1.6e-13 50.3 0.0 3.3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_1d PF00750.19 KKF92538.1 - 8.2e-99 330.8 7.4 3.1e-98 328.9 7.4 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KKF92538.1 - 1.4e-20 73.6 0.2 3.5e-20 72.4 0.2 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KKF92538.1 - 4.9e-06 27.0 0.0 1.3e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Ferric_reduct PF01794.19 KKF92539.1 - 7.5e-19 68.1 9.9 1e-18 67.6 8.6 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKF92539.1 - 1.7e-13 50.6 0.0 3.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KKF92539.1 - 5.9e-11 42.7 0.0 9.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain CesT PF05932.13 KKF92540.1 - 0.11 12.6 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family TPR_7 PF13176.6 KKF92541.1 - 3.3e-05 23.6 0.6 0.0045 16.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KKF92541.1 - 0.00087 19.7 4.1 0.00096 19.6 0.9 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKF92541.1 - 0.0013 19.2 0.4 0.0043 17.5 0.4 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKF92541.1 - 0.0014 19.2 5.0 0.0014 19.2 1.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKF92541.1 - 0.0033 17.4 0.2 0.074 13.2 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKF92541.1 - 0.004 17.9 7.4 0.015 16.0 0.4 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKF92541.1 - 0.0084 16.0 0.3 0.2 11.6 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKF92541.1 - 0.0094 16.5 1.0 0.096 13.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4192 PF13830.6 KKF92541.1 - 0.013 15.6 0.4 0.013 15.6 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) TPR_21 PF09976.9 KKF92541.1 - 0.037 13.7 0.9 0.061 13.0 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 KKF92541.1 - 0.078 13.3 1.4 0.53 10.6 0.3 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat YfdX PF10938.8 KKF92541.1 - 0.092 12.7 0.2 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 YfdX protein TPR_MalT PF17874.1 KKF92541.1 - 0.097 12.0 1.8 0.11 11.8 0.8 1.8 2 1 0 2 2 2 0 MalT-like TPR region TPR_8 PF13181.6 KKF92541.1 - 0.15 12.3 0.1 1.3 9.5 0.0 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.11 KKF92542.1 - 1.4e-08 35.3 0.1 1.4e-08 35.3 0.1 3.1 2 1 0 2 2 2 1 U3 snoRNA associated Utp14 PF04615.13 KKF92542.1 - 0.0066 15.1 20.6 0.0091 14.6 20.6 1.1 1 0 0 1 1 1 1 Utp14 protein Nop25 PF09805.9 KKF92542.1 - 9 6.8 23.7 0.21 12.0 13.4 2.3 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) bZIP_1 PF00170.21 KKF92543.1 - 0.0097 16.0 4.3 0.018 15.1 4.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor Stm1_N PF09598.10 KKF92544.1 - 9.9e-06 26.3 8.0 9.9e-06 26.3 8.0 3.8 5 1 0 5 5 5 1 Stm1 Bindin PF02084.15 KKF92544.1 - 6.9 6.9 13.3 0.7 10.1 4.1 2.2 2 0 0 2 2 2 0 Bindin MFS_1 PF07690.16 KKF92545.1 - 1.7e-15 56.8 40.3 5.5e-14 51.9 27.2 3.7 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKF92545.1 - 5.8e-07 28.4 21.1 9.3e-06 24.4 4.6 3.7 4 0 0 4 4 4 3 MFS/sugar transport protein Sugar_tr PF00083.24 KKF92545.1 - 0.55 9.0 8.4 0.16 10.8 0.7 3.1 4 0 0 4 4 4 0 Sugar (and other) transporter Actin PF00022.19 KKF92546.1 - 7.1e-28 97.3 0.0 5.9e-17 61.4 0.0 2.8 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KKF92546.1 - 3.4e-06 26.5 0.3 0.0049 16.1 0.0 2.3 2 0 0 2 2 2 2 Putative actin-like family PI-PLC-X PF00388.19 KKF92549.1 - 2.2e-63 212.2 0.0 3.3e-63 211.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KKF92549.1 - 2.9e-38 130.7 0.0 6e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain eIF3_subunit PF08597.10 KKF92549.1 - 0.0098 15.8 1.2 0.027 14.4 1.2 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit NRDE-2 PF08424.10 KKF92550.1 - 3.9e-58 197.1 0.6 5e-58 196.7 0.6 1.1 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference Voltage_CLC PF00654.20 KKF92552.1 - 7.1e-69 232.7 15.2 7.1e-69 232.7 15.2 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel Aminotran_3 PF00202.21 KKF92553.1 - 3.4e-119 398.1 0.0 3.8e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KKF92553.1 - 0.00093 18.5 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II TB2_DP1_HVA22 PF03134.19 KKF92554.1 - 7.1e-27 93.1 11.3 1.1e-26 92.5 11.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.12 KKF92555.1 - 1.9e-80 268.3 0.0 2.7e-80 267.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CHCH PF06747.13 KKF92555.1 - 6.7e-05 22.9 5.0 0.00014 21.9 5.0 1.6 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KKF92555.1 - 0.021 14.8 1.2 0.055 13.5 0.5 1.9 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0020 PF01170.18 KKF92555.1 - 0.039 13.6 0.1 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 BPL_N PF09825.9 KKF92556.1 - 1e-134 449.4 0.0 1.3e-134 449.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KKF92556.1 - 6.7e-23 81.0 0.0 1.4e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PKD_channel PF08016.12 KKF92556.1 - 0.27 9.9 10.3 1.5 7.5 1.5 2.2 2 0 0 2 2 2 0 Polycystin cation channel MFS_1 PF07690.16 KKF92557.1 - 3.1e-33 115.2 31.1 9.2e-33 113.6 31.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 KKF92557.1 - 4.7 7.1 7.3 38 4.2 0.3 4.0 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 KKF92558.1 - 0.0032 16.9 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CFEM PF05730.11 KKF92561.1 - 5e-08 32.9 10.1 7.4e-08 32.4 10.1 1.3 1 0 0 1 1 1 1 CFEM domain Pkinase PF00069.25 KKF92563.1 - 2.4e-56 191.1 0.0 3.1e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92563.1 - 8.4e-42 143.2 0.0 1.2e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKF92563.1 - 0.00011 21.3 0.0 0.0019 17.2 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KKF92563.1 - 0.0011 18.3 0.0 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KKF92563.1 - 0.0016 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KKF92563.1 - 0.018 15.0 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family PBP1_TM PF14812.6 KKF92565.1 - 0.092 13.1 0.2 9.3 6.7 1.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C4H2 PF10146.9 KKF92565.1 - 2.8 8.2 5.3 3.9 7.7 5.3 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein zf-C2H2 PF00096.26 KKF92566.1 - 0.39 11.3 4.2 4.5 7.9 0.7 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1059 PF06348.11 KKF92566.1 - 0.75 10.1 3.0 0.45 10.8 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) zf-TRAF PF02176.18 KKF92566.1 - 3.3 8.5 6.8 5.5 7.8 1.7 2.5 2 0 0 2 2 2 0 TRAF-type zinc finger GalKase_gal_bdg PF10509.9 KKF92567.1 - 1.7e-20 72.3 0.1 4.1e-20 71.1 0.1 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KKF92567.1 - 1.1e-13 51.1 2.7 1.1e-13 51.1 2.7 3.0 3 1 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKF92567.1 - 1.5e-12 47.7 0.1 3.6e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_23 PF13384.6 KKF92567.1 - 0.11 12.3 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain zf-RING_2 PF13639.6 KKF92568.1 - 0.025 14.9 1.2 0.054 13.8 1.2 1.6 1 1 0 1 1 1 0 Ring finger domain RINGv PF12906.7 KKF92568.1 - 0.046 13.9 0.6 0.081 13.1 0.6 1.4 1 0 0 1 1 1 0 RING-variant domain Cyt-b5 PF00173.28 KKF92569.1 - 1.8e-10 40.8 0.0 2.3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cpn10 PF00166.21 KKF92571.1 - 1.9e-29 101.6 0.0 2.1e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.25 KKF92572.1 - 2.5e-39 135.2 0.0 7.7e-35 120.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92572.1 - 2.2e-19 69.8 0.0 3.7e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKF92572.1 - 0.0033 17.4 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKF92572.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L11 PF00298.19 KKF92573.1 - 1.9e-26 92.3 0.0 3.1e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KKF92573.1 - 3.9e-26 90.7 0.4 6.1e-26 90.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain KH_8 PF17903.1 KKF92574.1 - 1.5e-28 98.7 0.0 2.9e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KKF92574.1 - 0.061 13.2 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 KH domain ADH_zinc_N PF00107.26 KKF92575.1 - 3.1e-23 82.2 0.6 5.8e-23 81.3 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKF92575.1 - 1.3e-07 32.8 0.1 5.5e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKF92575.1 - 5.9e-05 22.9 0.0 0.00015 21.6 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KKF92575.1 - 0.0025 17.1 2.2 0.0051 16.1 2.1 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KKF92575.1 - 0.0064 16.0 0.4 0.014 14.9 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase DASH_Ask1 PF08655.10 KKF92576.1 - 7.4e-24 83.4 0.3 2e-23 82.1 0.3 1.8 1 0 0 1 1 1 1 DASH complex subunit Ask1 MPLKIP PF15502.6 KKF92576.1 - 0.042 14.1 2.8 0.16 12.2 2.8 2.0 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein DGF-1_C PF11040.8 KKF92577.1 - 0.16 12.0 0.8 0.26 11.3 0.8 1.3 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Ribonuc_L-PSP PF01042.21 KKF92578.1 - 4.5e-26 91.2 0.1 5e-26 91.1 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4854 PF16146.5 KKF92578.1 - 0.056 13.8 0.0 1.3 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Sulf_transp PF04143.14 KKF92579.1 - 2.5e-34 119.2 24.6 2.5e-34 119.2 24.6 1.5 1 1 1 2 2 2 1 Sulphur transport WD40 PF00400.32 KKF92580.1 - 1.7e-27 95.1 11.9 3.5e-07 30.8 0.2 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat F-box-like PF12937.7 KKF92580.1 - 2.1e-11 43.5 1.1 4.6e-11 42.4 1.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KKF92580.1 - 8.9e-07 27.9 4.1 0.0087 14.7 0.2 3.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.33 KKF92580.1 - 2.1e-05 24.3 1.0 4.5e-05 23.2 1.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KKF92580.1 - 0.0017 18.6 0.7 0.43 10.9 0.1 3.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKF92580.1 - 0.093 12.0 0.1 0.42 9.9 0.0 1.8 1 1 1 2 2 2 0 WD40-like domain F_actin_cap_B PF01115.17 KKF92581.1 - 1.2e-103 345.8 0.0 1.4e-103 345.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit LptE PF04390.12 KKF92581.1 - 0.15 12.8 0.0 0.29 11.8 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide-assembly ATG22 PF11700.8 KKF92582.1 - 6.2e-112 374.7 14.1 1.2e-79 268.2 7.1 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.6 KKF92582.1 - 0.007 15.0 17.8 0.015 13.9 2.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein CTP_transf_like PF01467.26 KKF92583.1 - 5.4e-30 104.5 0.0 8.5e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like RRM_1 PF00076.22 KKF92584.1 - 1.2e-34 117.9 0.4 3.9e-16 58.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKF92584.1 - 1.9e-11 43.9 0.1 0.00015 21.8 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KKF92584.1 - 3.9e-05 23.5 0.1 0.017 15.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KKF92584.1 - 0.049 13.7 0.0 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif RabGAP-TBC PF00566.18 KKF92585.1 - 2.2e-49 168.0 0.0 4e-49 167.2 0.0 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Cullin_binding PF03556.15 KKF92585.1 - 0.45 11.0 2.8 0.64 10.5 1.5 1.9 3 0 0 3 3 3 0 Cullin binding SHNi-TPR PF10516.9 KKF92586.1 - 1.4e-14 53.2 8.2 3.9e-14 51.8 0.0 3.5 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 KKF92586.1 - 7.9e-08 32.5 5.8 5.8e-05 23.3 1.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKF92586.1 - 0.00027 20.8 15.7 0.0043 17.1 4.4 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKF92586.1 - 0.00033 21.3 0.8 0.00033 21.3 0.8 5.1 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKF92586.1 - 0.0027 17.5 5.6 0.015 15.1 3.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKF92586.1 - 0.014 15.9 1.2 0.014 15.9 1.2 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 KKF92586.1 - 0.016 15.3 3.3 0.083 13.0 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 KKF92586.1 - 0.021 15.1 2.3 0.69 10.2 0.7 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KKF92586.1 - 0.066 13.5 10.2 1.5 9.2 2.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat GMC_oxred_C PF05199.13 KKF92586.1 - 0.074 13.6 0.5 0.68 10.5 0.1 2.5 2 0 0 2 2 2 0 GMC oxidoreductase TPR_11 PF13414.6 KKF92586.1 - 0.13 12.0 12.2 0.057 13.1 4.9 3.6 5 0 0 5 5 5 0 TPR repeat TPR_17 PF13431.6 KKF92586.1 - 0.14 12.6 0.4 9.4 6.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 KKF92586.1 - 0.69 10.0 3.2 1.9 8.5 3.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KKF92586.1 - 8.5 6.4 9.4 3.1 7.8 2.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Mpp10 PF04006.12 KKF92587.1 - 7.4e-110 368.2 59.8 1.5e-109 367.2 59.8 1.4 1 1 0 1 1 1 1 Mpp10 protein AMPK1_CBM PF16561.5 KKF92588.1 - 5.6e-20 71.3 0.2 1.1e-19 70.4 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KKF92588.1 - 0.081 13.3 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) zf-C3HC4 PF00097.25 KKF92589.1 - 2.4e-07 30.5 2.5 6.5e-07 29.1 2.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKF92589.1 - 1e-06 28.6 0.8 1e-06 28.6 0.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKF92589.1 - 7.7e-06 25.8 3.8 1.5e-05 24.9 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KKF92589.1 - 3.3e-05 23.6 6.8 4.4e-05 23.2 2.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKF92589.1 - 6.7e-05 23.1 7.7 0.00036 20.8 8.0 2.0 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KKF92589.1 - 0.0001 22.1 8.6 0.00061 19.6 8.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KKF92589.1 - 0.00065 19.8 3.2 0.00065 19.8 3.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Lar_restr_allev PF14354.6 KKF92589.1 - 0.024 15.0 2.0 0.25 11.7 1.0 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar Prok-RING_4 PF14447.6 KKF92589.1 - 0.11 12.3 10.3 1.1 9.2 6.5 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KKF92589.1 - 0.2 11.8 5.5 0.1 12.8 2.9 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KKF92589.1 - 0.4 11.0 4.5 10 6.5 5.2 2.6 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KKF92589.1 - 3.8 7.5 4.8 2.2 8.2 1.0 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein G_glu_transpept PF01019.21 KKF92590.1 - 2.2e-130 435.9 0.0 2.5e-130 435.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glutaredoxin PF00462.24 KKF92591.1 - 1.8e-16 60.1 0.0 2.7e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin ArfGap PF01412.18 KKF92592.1 - 1.3e-37 128.4 0.4 1.3e-37 128.4 0.4 2.7 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.31 KKF92592.1 - 0.043 13.7 0.3 0.1 12.6 0.3 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Atrophin-1 PF03154.15 KKF92592.1 - 4.6 5.4 44.8 6.5 4.9 44.8 1.3 1 0 0 1 1 1 0 Atrophin-1 family Vma12 PF11712.8 KKF92592.1 - 8.5 6.4 6.6 0.53 10.3 0.6 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SCP2 PF02036.17 KKF92593.1 - 5.3e-23 81.4 0.6 6.1e-23 81.2 0.6 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KKF92593.1 - 9.7e-06 25.9 0.4 1.3e-05 25.5 0.4 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KKF92593.1 - 0.031 14.6 0.0 0.04 14.3 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain DUF1754 PF08555.10 KKF92593.1 - 2.8 8.8 7.1 1.4 9.8 4.2 1.9 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PI-PLC-X PF00388.19 KKF92595.1 - 1.5e-06 27.9 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF354 PF04007.12 KKF92595.1 - 0.037 13.1 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF354) Hydrolase PF00702.26 KKF92598.1 - 4.9e-05 23.7 0.0 6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KKF92599.1 - 4e-54 183.7 0.0 5.5e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92599.1 - 1.1e-33 116.7 0.0 1.6e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF92599.1 - 1.3e-13 50.9 0.0 2.4e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KKF92599.1 - 0.0018 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PilN_bio_d PF18222.1 KKF92599.1 - 0.017 15.5 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 PilN biogenesis protein dimerization domain Aa_trans PF01490.18 KKF92600.1 - 1.2e-33 116.4 17.2 1.8e-33 115.9 17.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein INCENP_ARK-bind PF03941.15 KKF92601.1 - 0.13 12.2 0.4 17 5.4 0.0 3.8 4 1 0 4 4 4 0 Inner centromere protein, ARK binding region Ntox50 PF15542.6 KKF92601.1 - 1.5 9.7 10.1 8 7.3 0.9 3.7 1 1 4 5 5 5 0 Bacterial toxin 50 WD40 PF00400.32 KKF92602.1 - 2.7e-55 183.1 8.9 9.7e-10 38.9 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92602.1 - 2.8e-14 53.2 0.0 0.0022 18.3 0.0 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF92602.1 - 6.7e-07 28.6 0.0 0.57 9.1 0.0 4.7 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KKF92602.1 - 3.4e-06 26.6 0.0 0.045 13.1 0.0 4.1 3 1 1 4 4 4 2 WD40-like domain Cytochrom_D1 PF02239.16 KKF92602.1 - 0.0045 15.6 0.3 0.52 8.8 0.1 2.8 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 KKF92602.1 - 0.0064 15.2 0.1 2.3 6.7 0.0 3.8 2 1 3 5 5 5 1 Nucleoporin Nup120/160 PD40 PF07676.12 KKF92602.1 - 0.012 15.6 0.2 16 5.6 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KKF92602.1 - 0.12 11.7 0.1 22 4.3 0.0 3.0 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Tup_N PF08581.10 KKF92602.1 - 0.13 12.6 0.3 0.21 11.9 0.3 1.3 1 0 0 1 1 1 0 Tup N-terminal FA_hydroxylase PF04116.13 KKF92603.1 - 1.3e-25 90.3 20.0 1.8e-25 89.8 16.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2015 PF09435.10 KKF92604.1 - 1.5e-43 147.2 0.0 1.7e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF668 PF05003.12 KKF92604.1 - 0.015 15.8 0.0 0.018 15.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF668) Ribosomal_L28e PF01778.17 KKF92605.1 - 3.9e-34 117.8 0.2 4.5e-34 117.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.18 KKF92606.1 - 1.2e-45 155.5 0.0 1.6e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KKF92606.1 - 2.2e-44 151.0 0.1 3e-44 150.5 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KKF92606.1 - 0.00017 20.7 0.0 0.00025 20.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KKF92606.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 KKF92606.1 - 0.027 13.8 0.0 0.18 11.1 0.0 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TRAPP PF04051.16 KKF92607.1 - 1.6e-41 141.4 0.0 2e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Herpes_capsid PF06112.11 KKF92607.1 - 3.9 7.5 8.3 6.1 6.9 8.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PRR18 PF15671.5 KKF92607.1 - 5.3 6.8 8.0 8.1 6.2 8.0 1.2 1 0 0 1 1 1 0 Proline-rich protein family 18 GATase_6 PF13522.6 KKF92611.1 - 1.6e-14 54.2 0.0 3.3e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KKF92611.1 - 2e-13 50.3 0.0 4e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KKF92611.1 - 1.1e-06 28.3 0.1 2e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KKF92611.1 - 0.0002 20.4 0.0 0.00032 19.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glyco_hydro_43 PF04616.14 KKF92612.1 - 9.2e-12 44.9 1.5 1.4e-11 44.3 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KKF92612.1 - 1.2e-05 25.1 0.1 5.3e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain PD40 PF07676.12 KKF92612.1 - 0.051 13.5 0.5 0.47 10.5 0.3 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Acyl_transf_3 PF01757.22 KKF92613.1 - 2.4e-15 56.4 27.2 3.3e-15 56.0 27.2 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF463 PF04317.12 KKF92613.1 - 0.26 10.2 0.1 0.43 9.4 0.1 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Aminotran_1_2 PF00155.21 KKF92614.1 - 2.1e-06 27.1 0.0 2.4e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pyr_redox_2 PF07992.14 KKF92615.1 - 1e-30 107.0 0.1 1.3e-30 106.7 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKF92615.1 - 2.8e-11 43.8 0.1 1.2e-07 32.2 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKF92615.1 - 4.7e-07 29.7 0.4 0.011 15.3 0.0 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKF92615.1 - 4.8e-06 26.7 0.0 0.035 14.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KKF92615.1 - 9.1e-06 25.0 0.0 0.00015 21.0 0.2 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KKF92615.1 - 8.8e-05 21.7 0.2 0.023 13.7 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Pro_Al_protease PF02983.14 KKF92615.1 - 0.0011 19.0 0.2 0.016 15.2 0.3 2.6 2 0 0 2 2 2 1 Alpha-lytic protease prodomain NAD_binding_8 PF13450.6 KKF92615.1 - 0.0064 16.7 0.1 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KKF92615.1 - 0.025 13.4 0.0 0.99 8.2 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Glyco_hydro_17 PF00332.18 KKF92616.1 - 1.6e-07 31.2 1.4 0.00047 19.9 0.3 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 WD40 PF00400.32 KKF92617.1 - 3.4e-21 75.2 4.9 8.9e-08 32.7 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92617.1 - 1.3e-06 28.6 0.3 0.72 10.2 0.0 4.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF92617.1 - 2.1e-05 23.7 0.0 0.16 10.9 0.0 2.9 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PUL PF08324.11 KKF92618.1 - 8e-55 186.0 0.0 1.2e-54 185.5 0.0 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KKF92618.1 - 1.4e-40 138.1 0.2 2.3e-40 137.4 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KKF92618.1 - 1.7e-25 88.8 5.9 8.4e-06 26.4 0.2 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat WD40_like PF17005.5 KKF92618.1 - 0.0015 17.9 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain PQQ_3 PF13570.6 KKF92618.1 - 0.026 15.0 0.0 0.18 12.3 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain Ge1_WD40 PF16529.5 KKF92618.1 - 0.064 12.2 0.1 17 4.2 0.0 3.7 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AOX PF01786.17 KKF92618.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Alternative oxidase WD40 PF00400.32 KKF92620.1 - 4.8e-07 30.4 0.5 0.17 12.8 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat CDC45 PF02724.14 KKF92620.1 - 6 5.0 17.5 8.4 4.5 17.5 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_12 PF13087.6 KKF92621.1 - 9.9e-29 100.4 0.0 1.6e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKF92621.1 - 2.2e-05 24.4 0.0 3.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKF92621.1 - 0.0021 17.8 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KKF92621.1 - 0.0051 16.3 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.18 KKF92621.1 - 0.0059 16.4 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KKF92621.1 - 0.022 15.1 0.0 0.065 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KKF92621.1 - 0.1 11.8 0.6 0.94 8.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KKF92621.1 - 0.15 11.7 0.0 0.41 10.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Malate_synthase PF01274.22 KKF92622.1 - 7.7e-230 763.6 0.0 8.7e-230 763.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 KKF92622.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Pkinase PF00069.25 KKF92623.1 - 4.6e-64 216.3 1.3 1.9e-62 211.0 1.3 2.5 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KKF92623.1 - 4.3e-36 123.2 0.3 8.5e-36 122.2 0.3 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KKF92623.1 - 5.9e-36 124.1 0.4 1.2e-35 123.0 0.4 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF92623.1 - 7.7e-07 28.7 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KKF92623.1 - 2.5e-05 23.4 0.1 4.1e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KKF92623.1 - 0.0023 17.9 0.0 0.0052 16.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKF92623.1 - 0.0037 16.9 0.2 0.0083 15.7 0.2 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KKF92623.1 - 0.011 15.1 0.2 0.023 14.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKF92623.1 - 0.015 14.9 0.3 0.055 13.0 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase SMC_N PF02463.19 KKF92624.1 - 3.4e-22 79.0 0.0 8.1e-22 77.7 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKF92624.1 - 1.5e-13 51.7 0.1 1.5e-13 51.7 0.1 5.3 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.6 KKF92624.1 - 4.8e-06 26.6 1.9 0.0014 18.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KKF92624.1 - 0.0038 17.0 12.4 0.0038 17.0 12.4 3.4 2 2 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KKF92624.1 - 0.0057 17.1 0.5 0.039 14.4 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF1748 PF08520.10 KKF92624.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) AAA_29 PF13555.6 KKF92624.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKF92624.1 - 0.055 13.4 1.0 0.66 9.9 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 KKF92624.1 - 0.11 13.0 0.0 0.11 13.0 0.0 5.0 4 2 1 5 5 3 0 ABC transporter Peptidase_S55 PF05580.12 KKF92624.1 - 0.13 12.2 0.1 10 6.0 0.1 3.1 2 0 0 2 2 2 0 SpoIVB peptidase S55 MMR_HSR1 PF01926.23 KKF92624.1 - 0.39 10.8 1.4 1.2 9.3 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fib_alpha PF08702.10 KKF92624.1 - 4.2 7.5 53.8 0.78 9.9 4.5 6.5 3 2 2 6 6 6 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KKF92624.1 - 6.5 6.8 47.9 2.5 8.1 3.7 7.7 5 2 3 9 9 9 0 Protein of unknown function (DUF1664) ApbA PF02558.16 KKF92625.1 - 1.1e-26 93.4 0.0 1.6e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KKF92625.1 - 3.3e-22 79.0 0.0 5.4e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pectate_lyase_3 PF12708.7 KKF92626.1 - 2.6e-101 337.9 20.6 2.6e-85 285.6 8.3 3.2 3 1 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KKF92626.1 - 8e-08 31.9 0.5 0.0089 15.7 0.1 3.3 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Scs3p PF10261.9 KKF92627.1 - 5.2e-59 199.7 9.2 1.6e-44 152.3 0.1 2.1 2 0 0 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM HypA PF01155.19 KKF92629.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Vel1p PF10339.9 KKF92629.1 - 0.091 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Yeast-specific zinc responsive Retrotrans_gag PF03732.17 KKF92630.1 - 0.00015 22.0 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Aldedh PF00171.22 KKF92631.1 - 3.2e-129 431.4 0.2 3.6e-129 431.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KKF92631.1 - 0.00064 18.9 0.0 0.00095 18.3 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) PALP PF00291.25 KKF92631.1 - 0.024 14.0 0.9 0.039 13.4 0.9 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DEAD PF00270.29 KKF92633.1 - 5.8e-45 153.2 0.9 9.5e-45 152.5 0.9 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF92633.1 - 8.1e-21 74.5 0.0 2.3e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKF92633.1 - 1.5e-15 57.1 0.0 3.4e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KKF92633.1 - 3.3e-06 27.2 0.0 8.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KKF92633.1 - 0.13 11.8 2.6 0.79 9.2 2.5 2.1 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain ERCC3_RAD25_C PF16203.5 KKF92633.1 - 0.14 11.4 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase VGLL4 PF15245.6 KKF92633.1 - 0.43 10.6 5.7 0.2 11.7 2.8 1.9 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 GHMP_kinases_N PF00288.26 KKF92634.1 - 7.5e-16 58.1 3.2 1.7e-15 57.0 3.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKF92634.1 - 6.6e-05 23.2 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Bclt PF15318.6 KKF92635.1 - 0.066 13.1 0.3 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis NMD3 PF04981.13 KKF92636.1 - 4.7e-81 271.8 4.2 6.5e-81 271.4 4.2 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 KKF92636.1 - 6.8 6.8 10.8 1.4e+03 -0.6 10.8 2.8 1 1 0 1 1 1 0 Double zinc ribbon RRM_1 PF00076.22 KKF92637.1 - 1.2e-07 31.4 0.0 1.3e-05 24.9 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SDA1 PF05285.12 KKF92637.1 - 0.00014 21.5 10.1 0.00014 21.5 10.1 2.1 2 0 0 2 2 2 1 SDA1 LAP1C PF05609.12 KKF92637.1 - 3.7 6.5 16.1 0.27 10.3 6.2 2.0 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 KKF92637.1 - 6.9 4.8 26.3 0.019 13.2 14.6 1.9 2 0 0 2 2 2 0 Nop14-like family PI-PLC-X PF00388.19 KKF92640.1 - 8.2e-08 32.0 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain zf-C2H2 PF00096.26 KKF92641.1 - 1.8e-09 37.5 13.7 5.9e-06 26.4 1.8 3.0 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKF92641.1 - 7.2e-06 26.2 10.5 8.6e-05 22.8 1.9 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKF92641.1 - 0.0017 19.1 1.4 0.0017 19.1 1.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KKF92641.1 - 0.002 18.4 1.1 0.01 16.2 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KKF92641.1 - 0.0028 17.6 0.3 0.0028 17.6 0.3 2.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKF92641.1 - 0.0056 16.9 2.4 0.017 15.4 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KKF92641.1 - 0.036 14.2 3.5 0.77 9.9 1.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 KKF92641.1 - 0.28 11.1 6.8 0.92 9.5 0.8 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_9 PF14369.6 KKF92641.1 - 3.1 8.1 7.0 18 5.7 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon MMR_HSR1 PF01926.23 KKF92642.1 - 2.5e-16 59.8 0.2 4.6e-15 55.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKF92642.1 - 7.7e-08 32.0 0.3 1.1e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKF92642.1 - 7e-07 29.3 0.0 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KKF92642.1 - 0.011 15.8 7.4 0.099 12.7 0.2 3.3 3 0 0 3 3 3 0 Dynamin family AIG1 PF04548.16 KKF92642.1 - 0.016 14.5 0.1 0.03 13.7 0.1 1.4 1 0 0 1 1 1 0 AIG1 family Sporozoite_P67 PF05642.11 KKF92642.1 - 0.02 13.0 0.1 0.027 12.6 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_Rpc4 PF05132.14 KKF92642.1 - 0.023 15.1 0.8 0.023 15.1 0.8 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 MeaB PF03308.16 KKF92642.1 - 0.13 11.2 0.1 0.5 9.3 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pox_Ag35 PF03286.14 KKF92642.1 - 0.33 10.7 7.9 0.7 9.7 7.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 KKF92642.1 - 0.41 9.3 3.2 0.69 8.6 3.2 1.3 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 KKF92642.1 - 0.52 9.0 4.2 0.81 8.4 4.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 KKF92642.1 - 1.4 7.2 8.3 1.9 6.7 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 KKF92642.1 - 1.7 8.8 5.7 4.8 7.3 5.7 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MRNIP PF15749.5 KKF92642.1 - 4.3 8.1 6.9 15 6.4 4.5 2.4 2 0 0 2 2 2 0 MRN-interacting protein Spore_coat_CotO PF14153.6 KKF92642.1 - 6.7 6.6 12.3 16 5.4 12.3 1.5 1 0 0 1 1 1 0 Spore coat protein CotO LTV PF04180.14 KKF92643.1 - 5.2e-97 326.0 15.1 5.9e-97 325.8 15.1 1.0 1 0 0 1 1 1 1 Low temperature viability protein SAC3_GANP PF03399.16 KKF92644.1 - 4.1e-86 289.0 0.0 6.5e-86 288.3 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family FPN1 PF06963.12 KKF92644.1 - 2.4e-85 286.7 1.3 3.5e-85 286.2 1.3 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) LepA_C PF06421.12 KKF92644.1 - 0.24 11.5 2.3 0.54 10.4 2.3 1.5 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus ParBc PF02195.18 KKF92644.1 - 0.4 11.0 3.5 1.7 9.0 3.5 2.1 1 0 0 1 1 1 0 ParB-like nuclease domain Amidohydro_2 PF04909.14 KKF92645.1 - 0.08 12.7 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase NMO PF03060.15 KKF92646.1 - 2.8e-55 188.0 0.7 3.6e-54 184.4 0.7 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKF92646.1 - 8e-13 48.1 0.6 1.4e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKF92646.1 - 0.00029 20.0 0.2 0.00048 19.3 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NIL PF09383.10 KKF92646.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 NIL domain NanE PF04131.14 KKF92646.1 - 0.092 11.9 0.0 0.092 11.9 0.0 2.0 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Dioxygenase_C PF00775.21 KKF92647.1 - 9.3e-42 142.5 0.0 1.2e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KKF92647.1 - 3.7e-26 90.8 0.0 5.6e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus PTCB-BRCT PF12738.7 KKF92648.1 - 2.6e-31 107.3 1.7 5.8e-21 74.2 0.2 4.7 4 0 0 4 4 4 3 twin BRCT domain RTT107_BRCT_5 PF16770.5 KKF92648.1 - 7e-28 96.5 0.0 3.5e-25 87.8 0.0 3.6 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KKF92648.1 - 9.5e-24 83.6 0.0 4.6e-08 33.3 0.0 5.5 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKF92648.1 - 3.3e-18 65.9 0.0 0.00054 20.3 0.0 5.3 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain Lactonase PF10282.9 KKF92648.1 - 2.2e-16 60.0 0.0 3.9e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller BRCT_3 PF18428.1 KKF92648.1 - 1.7e-07 31.2 0.0 0.0024 17.9 0.0 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KKF92648.1 - 3.3e-05 24.1 0.0 0.97 9.8 0.0 3.6 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain ESCRT-II PF05871.12 KKF92649.1 - 1.9e-33 115.7 0.0 4.5e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 ESCRT-II complex subunit DUF2014 PF09427.10 KKF92649.1 - 4.8e-22 78.6 4.5 5.4e-13 48.9 3.3 3.3 1 1 2 3 3 3 3 Domain of unknown function (DUF2014) HLH PF00010.26 KKF92649.1 - 1.6e-15 56.8 3.1 1.6e-15 56.8 0.6 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain UvrD_C PF13361.6 KKF92651.1 - 3.6e-57 194.3 0.3 7.4e-57 193.3 0.3 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KKF92651.1 - 2.5e-28 99.5 0.3 9e-28 97.7 0.0 2.0 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KKF92651.1 - 1.2e-14 53.8 0.0 2.4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KKF92651.1 - 4.2e-12 46.6 0.0 1.1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KKF92651.1 - 7.2e-06 25.9 0.0 0.11 12.2 0.0 2.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KKF92651.1 - 2.1e-05 24.3 0.1 7e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKF92651.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ceramidase_alk PF04734.13 KKF92652.1 - 6e-198 658.6 1.9 1.6e-195 650.6 1.9 2.0 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KKF92652.1 - 4e-55 186.2 0.0 6.5e-55 185.6 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Peptidase_M28 PF04389.17 KKF92653.1 - 1.3e-14 54.4 0.0 1.8e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Aa_trans PF01490.18 KKF92654.1 - 6.5e-80 268.8 28.5 1.1e-79 268.1 28.5 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAP2 PF01569.21 KKF92654.1 - 1.2e-10 41.3 2.0 1.2e-10 41.3 2.0 3.0 4 1 0 4 4 4 1 PAP2 superfamily DUF212 PF02681.14 KKF92654.1 - 0.016 15.4 1.1 0.35 11.0 0.0 2.7 3 0 0 3 3 3 0 Divergent PAP2 family EBP PF05241.12 KKF92656.1 - 2.5e-62 209.5 6.7 2.9e-62 209.3 6.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein CRM1_repeat_3 PF18787.1 KKF92656.1 - 0.043 13.9 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 NADH_dh_m_C1 PF15088.6 KKF92656.1 - 0.091 12.4 0.6 0.3 10.7 0.6 1.8 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Grg1 PF11034.8 KKF92657.1 - 1.1e-32 112.0 9.6 1.2e-32 111.9 9.6 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 mono-CXXC PF15626.6 KKF92657.1 - 0.068 13.5 1.8 1.3 9.4 0.3 2.0 1 1 1 2 2 2 0 single CXXC unit WD40 PF00400.32 KKF92658.1 - 3.7e-11 43.4 0.1 0.24 12.3 0.1 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat Dicty_REP PF05086.12 KKF92658.1 - 0.35 8.8 0.8 0.47 8.4 0.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cwf_Cwc_15 PF04889.12 KKF92658.1 - 2.9 7.6 8.0 4.8 6.8 1.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 KKF92659.1 - 1.9e-38 132.4 0.0 2.9e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92659.1 - 1.6e-27 96.4 0.0 2.2e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKF92659.1 - 0.00052 19.4 0.0 0.00087 18.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKF92659.1 - 0.012 15.6 0.2 2.4 8.0 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKF92659.1 - 0.11 11.3 0.4 0.23 10.2 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Cas_csx3 PF09620.10 KKF92660.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Cas_csx3 PF09620.10 KKF92661.1 - 0.006 16.4 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_csx3) NACHT_N PF17100.5 KKF92662.1 - 2.9e-60 203.9 0.9 3.2e-60 203.7 0.0 1.5 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 KKF92662.1 - 5.6e-33 112.4 8.4 7e-11 42.5 0.3 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.12 KKF92662.1 - 5.1e-14 52.5 0.1 3.4e-13 49.8 0.0 2.2 3 0 0 3 3 3 1 NACHT domain ANAPC4_WD40 PF12894.7 KKF92662.1 - 7.1e-13 48.7 1.0 0.0061 16.8 0.1 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF92662.1 - 7.8e-07 28.4 1.6 0.072 12.0 0.0 3.2 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Robl_LC7 PF03259.17 KKF92662.1 - 0.00024 20.8 1.4 3.2 7.6 0.0 4.2 2 1 2 4 4 4 1 Roadblock/LC7 domain AAA_22 PF13401.6 KKF92662.1 - 0.0021 18.4 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain XPC-binding PF09280.11 KKF92662.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 XPC-binding domain Nup160 PF11715.8 KKF92662.1 - 0.011 14.4 1.9 0.92 8.1 0.2 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 KKF92662.1 - 0.012 15.5 0.0 48 4.1 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat AAA_19 PF13245.6 KKF92662.1 - 0.018 15.4 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKF92662.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF484 PF04340.12 KKF92662.1 - 0.048 13.3 0.2 0.17 11.6 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF484 AAA_11 PF13086.6 KKF92662.1 - 0.068 12.9 4.6 0.19 11.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain DHR10 PF18595.1 KKF92662.1 - 0.21 11.7 5.9 0.39 10.8 5.9 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Big_7 PF17957.1 KKF92662.1 - 0.75 10.6 7.4 32 5.4 1.0 3.4 1 1 1 2 2 2 0 Bacterial Ig domain RAC_head PF16717.5 KKF92663.1 - 5.2e-29 101.1 4.2 5.2e-29 101.1 4.2 4.0 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KKF92663.1 - 2.5e-18 66.0 0.4 1.1e-17 63.8 0.4 2.2 1 0 0 1 1 1 1 DnaJ domain TraH PF06122.11 KKF92663.1 - 0.058 12.7 3.8 0.1 11.9 3.8 1.4 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Sterol_MT_C PF08498.10 KKF92664.1 - 1.5e-27 95.7 0.4 2.5e-27 95.0 0.4 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KKF92664.1 - 2.2e-22 79.5 0.0 4.4e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF92664.1 - 4.2e-20 72.3 0.0 9.2e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF92664.1 - 3.4e-19 69.1 0.0 5.1e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF92664.1 - 1.2e-13 51.3 0.0 2.1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF92664.1 - 5.8e-13 49.4 0.0 1.3e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKF92664.1 - 1e-11 44.7 0.0 1.6e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KKF92664.1 - 4e-11 42.7 0.0 7.2e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KKF92664.1 - 0.00016 21.3 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 KKF92664.1 - 0.00022 21.0 0.0 0.00036 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KKF92664.1 - 0.00055 19.4 0.0 0.0016 17.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KKF92664.1 - 0.002 17.7 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KKF92664.1 - 0.0031 16.9 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 KKF92664.1 - 0.0036 15.9 0.0 0.005 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 KKF92664.1 - 0.0053 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KKF92664.1 - 0.0085 16.1 0.7 0.018 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 KKF92664.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.20 KKF92664.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 KKF92664.1 - 0.038 13.5 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase GRIP PF01465.20 KKF92665.1 - 9.2e-12 44.7 0.1 2.1e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 GRIP domain GAS PF13851.6 KKF92665.1 - 1.2e-05 24.8 127.1 0.00076 18.9 9.5 7.9 2 2 5 7 7 7 5 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KKF92665.1 - 0.0044 15.9 135.7 0.034 13.0 17.9 6.8 2 2 5 7 7 7 4 Spc7 kinetochore protein HrpB7 PF09486.10 KKF92665.1 - 0.015 15.7 16.6 0.015 15.7 16.6 8.5 2 2 4 7 7 7 0 Bacterial type III secretion protein (HrpB7) NPV_P10 PF05531.12 KKF92665.1 - 1.5 9.3 58.4 0.71 10.4 0.2 11.0 4 3 3 9 9 9 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 KKF92665.1 - 3.4 7.2 117.3 0.11 12.1 4.4 6.6 2 2 4 6 6 6 0 Mechanosensitive ion channel porin domain ATG16 PF08614.11 KKF92665.1 - 5.1 7.3 144.6 1.2 9.3 11.0 8.1 2 2 5 8 8 8 0 Autophagy protein 16 (ATG16) Protoglobin PF11563.8 KKF92666.1 - 3.2e-48 163.6 0.0 3.8e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Med26 PF08711.11 KKF92668.1 - 7.5e-11 41.9 0.0 1.8e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain MFS_1 PF07690.16 KKF92669.1 - 1.4e-35 122.9 19.3 1.4e-35 122.9 19.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily HLH PF00010.26 KKF92670.1 - 1.2e-17 63.6 0.1 2.4e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4552 PF15089.6 KKF92670.1 - 0.0065 15.6 3.7 0.012 14.7 3.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4552) bZIP_1 PF00170.21 KKF92670.1 - 0.016 15.3 1.3 0.045 13.9 0.2 2.1 2 0 0 2 2 2 0 bZIP transcription factor TERB2 PF15101.6 KKF92670.1 - 0.03 14.4 0.9 0.03 14.4 0.9 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DivIC PF04977.15 KKF92670.1 - 2.4 8.0 11.9 0.28 11.0 0.3 3.2 3 1 1 4 4 4 0 Septum formation initiator VIT PF08487.10 KKF92671.1 - 6.6e-30 103.6 0.4 1.4e-29 102.5 0.4 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KKF92671.1 - 7.3e-27 94.2 0.0 1.7e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KKF92671.1 - 2e-11 44.5 0.0 5.2e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KKF92671.1 - 4.1e-09 36.2 0.1 9.2e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 KKF92671.1 - 4.4e-08 33.7 0.1 1.6e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KKF92671.1 - 0.0011 18.4 0.0 0.0033 16.9 0.0 1.8 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein AA_permease PF00324.21 KKF92672.1 - 9.2e-117 390.5 44.5 1.1e-116 390.2 44.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKF92672.1 - 4.6e-23 81.7 47.4 6.4e-23 81.3 47.4 1.2 1 0 0 1 1 1 1 Amino acid permease PI-PLC-X PF00388.19 KKF92673.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Tektin PF03148.14 KKF92674.1 - 0.002 17.0 4.6 0.0028 16.5 4.6 1.2 1 0 0 1 1 1 1 Tektin family Retrotrans_gag PF03732.17 KKF92674.1 - 0.011 16.0 0.2 0.011 16.0 0.2 2.7 2 2 0 2 2 2 0 Retrotransposon gag protein Cut12 PF11500.8 KKF92674.1 - 0.015 15.3 0.2 0.015 15.3 0.2 2.1 1 1 1 2 2 2 0 Spindle pole body formation-associated protein Dna2 PF08696.11 KKF92674.1 - 0.025 14.4 0.7 0.042 13.7 0.7 1.5 1 0 0 1 1 1 0 DNA replication factor Dna2 Arm-DNA-bind_5 PF17293.2 KKF92674.1 - 1.7 9.1 6.4 53 4.3 6.4 2.5 1 1 0 1 1 1 0 Arm DNA-binding domain DUF3450 PF11932.8 KKF92674.1 - 1.8 7.8 11.3 2.6 7.3 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PI-PLC-X PF00388.19 KKF92675.1 - 4.2e-05 23.2 0.0 7.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-X PF00388.19 KKF92676.1 - 7.1e-10 38.6 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain p450 PF00067.22 KKF92677.1 - 3.2e-50 171.2 0.0 6.9e-44 150.4 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Aminotran_1_2 PF00155.21 KKF92678.1 - 1e-18 67.7 0.0 1.4e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KKF92678.1 - 9.7e-05 21.3 0.0 0.00028 19.8 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KKF92678.1 - 0.0063 15.9 0.1 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.16 KKF92679.1 - 8.1e-15 54.6 32.2 8.1e-15 54.6 32.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KKF92679.1 - 2.3e-13 50.1 8.5 8.3e-13 48.3 7.8 2.3 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KKF92679.1 - 0.0067 15.3 6.5 0.0067 15.3 6.5 2.3 2 1 0 2 2 2 1 MFS_1 like family FAD_binding_4 PF01565.23 KKF92680.1 - 1.2e-25 89.9 0.8 2.1e-25 89.1 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain Hist_deacetyl PF00850.19 KKF92683.1 - 1.4e-52 179.1 0.4 2e-52 178.6 0.4 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 KKF92683.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RTP801 C-terminal region ABC_tran PF00005.27 KKF92684.1 - 1.1e-28 100.5 0.2 2e-28 99.6 0.2 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KKF92684.1 - 1.8e-26 93.4 24.1 2.7e-15 56.8 9.3 3.4 2 1 1 3 3 3 3 ABC transporter transmembrane region DUF87 PF01935.17 KKF92684.1 - 0.00034 20.8 0.9 0.00057 20.0 0.1 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain SMC_N PF02463.19 KKF92684.1 - 0.002 17.6 0.4 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKF92684.1 - 0.0055 16.4 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain PAP2 PF01569.21 KKF92684.1 - 0.011 15.5 4.4 0.026 14.3 0.2 3.3 1 1 0 2 2 2 0 PAP2 superfamily MMR_HSR1 PF01926.23 KKF92684.1 - 0.012 15.6 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KKF92684.1 - 0.033 13.5 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.7 KKF92684.1 - 0.039 12.9 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain GCIP PF13324.6 KKF92684.1 - 0.12 12.0 0.2 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting AAA_7 PF12775.7 KKF92684.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KKF92684.1 - 0.16 11.2 0.1 0.35 10.0 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 KKF92684.1 - 0.16 12.5 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKF92684.1 - 0.23 11.4 0.6 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.6 KKF92684.1 - 0.31 11.4 1.9 0.81 10.0 0.6 2.4 2 1 0 2 2 2 0 AAA ATPase domain DUF1471 PF07338.13 KKF92684.1 - 0.43 10.6 2.5 1.2 9.1 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Methyltr_RsmB-F PF01189.17 KKF92685.1 - 1.3e-29 103.3 0.0 1.8e-23 83.2 0.0 2.5 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KKF92685.1 - 0.022 14.9 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase SAPS PF04499.15 KKF92685.1 - 1.6 7.4 4.8 0.2 10.4 0.8 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein GTP1_OBG PF01018.22 KKF92686.1 - 4.3e-40 136.8 1.0 1.2e-29 102.9 3.0 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KKF92686.1 - 1.2e-21 76.9 0.0 2.1e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKF92686.1 - 9.1e-07 28.5 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 KKF92686.1 - 0.016 15.7 0.0 0.03 14.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KKF92686.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain BLACT_WH PF17778.1 KKF92687.1 - 0.089 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain EzrA PF06160.12 KKF92688.1 - 1.9e-05 23.0 13.5 1.9e-05 23.0 13.5 2.8 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 KKF92688.1 - 0.011 16.0 1.1 0.011 16.0 1.1 5.0 4 3 1 5 5 5 0 ABC transporter C-terminal domain CorA PF01544.18 KKF92688.1 - 0.48 9.7 11.7 0.012 14.9 4.0 2.2 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein HalX PF08663.10 KKF92688.1 - 0.66 10.3 18.4 0.53 10.6 0.6 5.1 3 1 2 5 5 5 0 HalX domain Occludin_ELL PF07303.13 KKF92688.1 - 3.6 8.4 30.4 0.21 12.3 0.8 4.7 2 1 3 5 5 5 0 Occludin homology domain RNA_pol_Rpb5_C PF01191.19 KKF92689.1 - 4.6e-32 109.7 0.1 8.2e-32 108.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KKF92689.1 - 5e-22 78.3 0.1 7.7e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KKF92689.1 - 0.0081 16.2 0.1 0.022 14.8 0.0 1.8 3 0 0 3 3 3 1 Restriction endonuclease BCDHK_Adom3 PF10436.9 KKF92689.1 - 0.014 15.3 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase ArsA_HSP20 PF17886.1 KKF92689.1 - 0.12 11.9 0.1 1 8.9 0.0 2.3 2 1 0 2 2 2 0 HSP20-like domain found in ArsA Utp21 PF04192.12 KKF92691.1 - 1.1e-72 244.3 0.4 1.9e-72 243.5 0.4 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain PI3_PI4_kinase PF00454.27 KKF92691.1 - 5.1e-44 151.0 0.0 8.3e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase WD40 PF00400.32 KKF92691.1 - 4.3e-15 55.8 21.0 0.00026 21.7 0.2 7.9 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92691.1 - 5.5e-12 45.8 0.0 0.0017 18.6 0.0 5.6 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KKF92691.1 - 0.00028 19.9 0.1 0.049 12.6 0.0 2.8 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KKF92691.1 - 0.0011 17.7 0.6 0.085 11.5 0.2 2.9 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KKF92691.1 - 0.0016 17.1 0.2 0.0048 15.5 0.0 1.7 2 0 0 2 2 2 1 Cytochrome D1 heme domain His_Phos_2 PF00328.22 KKF92692.1 - 1e-89 301.6 0.2 1.3e-88 298.0 0.2 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KKF92692.1 - 6.2e-37 125.6 0.0 1.5e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KKF92692.1 - 1.8e-05 24.4 0.0 3.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Tox-REase-3 PF15647.6 KKF92693.1 - 0.13 12.6 0.1 0.3 11.4 0.1 1.6 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 3 ThiJ_like PF17124.5 KKF92694.1 - 2.4e-24 86.1 0.0 3.6e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KKF92694.1 - 0.036 13.9 0.0 0.073 12.9 0.0 1.6 1 1 0 1 1 1 0 DJ-1/PfpI family RPAP1_C PF08620.10 KKF92695.1 - 3.6e-25 87.8 0.0 5.9e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KKF92695.1 - 7.8e-16 57.6 10.0 9.9e-16 57.2 8.8 1.8 2 0 0 2 2 2 1 RPAP1-like, N-terminal Pyridoxal_deC PF00282.19 KKF92696.1 - 7.8e-72 242.0 0.0 1.1e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KKF92696.1 - 0.0038 16.5 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KKF92696.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V F-box-like PF12937.7 KKF92697.1 - 1e-09 38.1 0.6 2.4e-09 36.9 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKF92697.1 - 1.8e-09 37.2 1.0 9.8e-09 34.9 0.6 2.4 1 1 1 2 2 2 1 F-box domain WD40 PF00400.32 KKF92697.1 - 5.9e-08 33.3 0.4 0.058 14.3 0.0 3.6 3 1 0 3 3 3 2 WD domain, G-beta repeat F-box_4 PF15966.5 KKF92697.1 - 0.017 15.0 0.1 0.047 13.6 0.1 1.7 1 0 0 1 1 1 0 F-box FF PF01846.19 KKF92698.1 - 1.5e-07 31.5 0.5 1.5e-07 31.5 0.5 3.1 3 1 0 3 3 3 1 FF domain Proteasome PF00227.26 KKF92699.1 - 5.9e-61 205.3 0.1 7.3e-61 205.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKF92699.1 - 2.9e-13 49.2 0.1 8.7e-13 47.7 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KKF92699.1 - 0.018 15.1 0.5 0.06 13.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 KKF92699.1 - 0.041 13.4 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SPOC PF07744.13 KKF92700.1 - 1.2e-20 74.0 0.0 2.1e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KKF92700.1 - 3.2e-18 66.2 0.6 7.7e-18 65.0 0.6 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KKF92700.1 - 1.4e-09 37.7 8.8 2.7e-09 36.8 8.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKF92700.1 - 0.033 13.7 4.2 0.062 12.9 4.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 KKF92700.1 - 0.13 12.3 2.8 0.34 11.0 2.8 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger DUF747 PF05346.11 KKF92701.1 - 2.6e-94 316.3 3.2 3.1e-94 316.0 3.2 1.0 1 0 0 1 1 1 1 Eukaryotic membrane protein family LAMTOR PF15454.6 KKF92702.1 - 3.2e-06 27.6 0.0 1e-05 26.1 0.0 1.8 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator TrpBP PF02081.15 KKF92702.1 - 0.097 12.5 0.3 0.76 9.6 0.0 2.3 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein CUE PF02845.16 KKF92703.1 - 4.2e-06 26.3 0.0 7.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 KKF92703.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) Pkinase PF00069.25 KKF92709.1 - 6.1e-53 179.9 0.0 8.5e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92709.1 - 1.7e-32 112.7 0.0 2.3e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF92709.1 - 0.00075 18.9 0.0 0.003 16.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KKF92709.1 - 0.004 17.1 0.2 0.0087 16.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KKF92709.1 - 0.034 13.1 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KKF92709.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKF92709.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Sushi_2 PF09014.10 KKF92709.1 - 0.19 11.6 0.7 0.49 10.3 0.1 1.9 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Glycos_transf_2 PF00535.26 KKF92710.1 - 2.3e-33 115.4 0.0 4e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 TMA7 PF09072.10 KKF92710.1 - 4.8e-22 78.5 17.9 8e-22 77.8 17.9 1.4 1 0 0 1 1 1 1 Translation machinery associated TMA7 Glyco_tranf_2_3 PF13641.6 KKF92710.1 - 6e-13 49.2 0.0 1.1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KKF92710.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KKF92710.1 - 0.0018 17.7 0.0 0.0043 16.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 RSN1_7TM PF02714.15 KKF92711.1 - 4.2e-72 242.7 18.2 9.5e-72 241.6 18.2 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKF92711.1 - 6.5e-39 133.2 2.3 1.7e-38 131.8 2.3 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKF92711.1 - 4.7e-36 124.6 0.0 7.1e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter AATase PF07247.12 KKF92712.1 - 5.4e-07 28.5 0.0 3.1e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase DUF2834 PF11196.8 KKF92715.1 - 0.00027 21.2 0.9 0.13 12.6 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) Pkinase PF00069.25 KKF92716.1 - 6.9e-49 166.6 0.0 2.4e-48 164.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92716.1 - 7.9e-33 113.8 0.0 1.2e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF92716.1 - 0.0001 21.7 0.0 0.00024 20.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KKF92716.1 - 0.00011 21.2 0.1 0.00023 20.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KKF92716.1 - 0.0084 16.0 0.1 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pacs-1 PF10254.9 KKF92716.1 - 0.011 14.7 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein zf-C2H2_assoc3 PF16637.5 KKF92716.1 - 0.11 12.7 0.2 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz Sybindin PF04099.12 KKF92717.1 - 2.6e-23 82.5 0.0 3.2e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KKF92717.1 - 0.18 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region NUC153 PF08159.12 KKF92718.1 - 5.9e-10 38.8 3.3 2.3e-09 36.9 3.5 1.9 2 0 0 2 2 2 1 NUC153 domain WD40 PF00400.32 KKF92718.1 - 3.2e-05 24.6 0.2 2.3 9.2 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat FAM27 PF15832.5 KKF92718.1 - 0.47 11.0 3.9 16 6.1 0.0 2.9 2 1 0 2 2 2 0 FAM27 D and E protein family Peroxin-3 PF04882.12 KKF92719.1 - 1.3e-156 522.3 0.4 3.1e-155 517.7 0.4 2.0 1 1 0 1 1 1 1 Peroxin-3 ATG101 PF07855.12 KKF92720.1 - 8.3e-17 61.6 0.2 9.6e-17 61.4 0.2 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 B3_4 PF03483.17 KKF92720.1 - 0.019 14.6 0.1 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 B3/4 domain RPN13_C PF16550.5 KKF92720.1 - 0.041 14.0 0.1 3.6 7.8 0.0 2.0 1 1 1 2 2 2 0 UCH-binding domain Forkhead PF00250.18 KKF92721.1 - 1.6e-33 114.8 0.0 2.6e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain CCDC106 PF15794.5 KKF92723.1 - 0.0024 17.7 2.2 0.0024 17.7 2.2 1.8 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 106 CENP-Q PF13094.6 KKF92723.1 - 0.0069 16.6 8.9 0.01 16.1 8.9 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.19 KKF92723.1 - 0.0091 14.0 2.5 0.0098 13.9 2.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family AbiH PF14253.6 KKF92723.1 - 0.019 14.9 1.4 0.022 14.6 1.4 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF573 PF04504.14 KKF92723.1 - 0.023 15.4 1.0 0.043 14.5 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF573 DASH_Spc19 PF08287.11 KKF92723.1 - 0.094 12.6 6.6 0.18 11.7 6.6 1.5 1 0 0 1 1 1 0 Spc19 DUF572 PF04502.13 KKF92723.1 - 0.17 11.5 9.6 0.2 11.3 9.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) MCU PF04678.13 KKF92723.1 - 0.24 11.5 2.8 0.3 11.2 2.8 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4446 PF14584.6 KKF92723.1 - 0.25 11.3 3.5 0.35 10.8 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) UPF0242 PF06785.11 KKF92723.1 - 0.32 11.1 5.4 0.38 10.8 5.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 KKF92723.1 - 0.34 10.7 8.4 0.64 9.8 8.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Cep57_CLD_2 PF14197.6 KKF92723.1 - 0.41 10.8 9.2 0.7 10.0 9.2 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 AKNA PF12443.8 KKF92723.1 - 0.49 11.1 6.1 1.5 9.5 6.1 1.8 1 1 0 1 1 1 0 AT-hook-containing transcription factor Plasmodium_Vir PF05795.11 KKF92723.1 - 1.2 8.5 4.2 1.3 8.3 4.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein APG6_N PF17675.1 KKF92723.1 - 8.7 6.9 17.0 12 6.4 17.0 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Med7 PF05983.11 KKF92724.1 - 1.7e-56 191.3 0.9 2.2e-56 191.0 0.9 1.1 1 0 0 1 1 1 1 MED7 protein Dynactin_p22 PF07426.11 KKF92724.1 - 0.039 13.8 0.5 0.08 12.8 0.5 1.7 1 1 0 1 1 1 0 Dynactin subunit p22 DUF615 PF04751.14 KKF92724.1 - 0.05 13.6 0.7 0.13 12.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF615) AMP-binding PF00501.28 KKF92725.1 - 3e-22 78.8 0.0 4.5e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KKF92725.1 - 2.9e-08 32.8 0.2 9.3e-08 31.2 0.2 1.7 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KKF92725.1 - 0.00047 20.4 0.2 0.0012 19.2 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KKF92725.1 - 0.031 15.3 0.0 0.08 13.9 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain zf-C2H2 PF00096.26 KKF92726.1 - 2e-06 27.9 27.7 0.00046 20.5 1.1 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKF92726.1 - 0.0017 19.1 1.0 0.0017 19.1 1.0 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKF92726.1 - 0.012 15.6 0.2 0.012 15.6 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SUIM_assoc PF16619.5 KKF92726.1 - 0.61 10.2 6.1 3.4 7.8 0.9 3.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Glyco_hydro_47 PF01532.20 KKF92727.1 - 1.4e-163 545.0 0.1 1.8e-163 544.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4064 PF13273.6 KKF92729.1 - 0.00065 19.9 0.5 0.00078 19.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF1282 PF06930.12 KKF92729.1 - 0.0038 17.0 0.1 0.0039 17.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) MIP PF00230.20 KKF92729.1 - 0.045 13.4 0.5 0.05 13.3 0.5 1.1 1 0 0 1 1 1 0 Major intrinsic protein SecE PF00584.20 KKF92729.1 - 0.19 11.6 0.2 0.19 11.6 0.2 2.0 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Shisa PF13908.6 KKF92730.1 - 0.0084 16.4 0.0 0.05 13.9 0.0 2.1 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator UCR_hinge PF02320.16 KKF92731.1 - 8.2e-26 90.0 3.3 1.6e-25 89.1 3.3 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein KIND PF16474.5 KKF92731.1 - 0.0093 15.9 1.7 0.013 15.4 1.7 1.2 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain GCIP PF13324.6 KKF92731.1 - 0.022 14.4 1.1 0.024 14.3 1.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 KKF92731.1 - 0.05 14.0 10.4 0.091 13.2 10.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KKF92731.1 - 0.064 12.9 1.1 0.084 12.5 1.1 1.2 1 0 0 1 1 1 0 FAM176 family Latrophilin PF02354.16 KKF92731.1 - 0.098 11.7 0.4 0.1 11.6 0.4 1.1 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region EBV-NA3 PF05009.12 KKF92731.1 - 0.15 11.6 5.5 0.22 11.0 5.5 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Sporozoite_P67 PF05642.11 KKF92731.1 - 0.18 9.9 1.8 0.19 9.8 1.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4611 PF15387.6 KKF92731.1 - 0.19 12.0 6.6 0.24 11.7 5.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Radial_spoke PF04712.12 KKF92731.1 - 0.44 9.4 5.8 0.55 9.1 5.8 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 KKF92731.1 - 0.46 8.5 7.0 0.56 8.2 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KKF92731.1 - 2.2 6.4 6.1 2.5 6.2 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family Adeno_terminal PF02459.15 KKF92731.1 - 3.1 6.1 4.9 3.4 6.0 4.9 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PTPRCAP PF15713.5 KKF92731.1 - 3.7 7.8 10.3 1.4 9.2 7.2 1.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Sigma70_ner PF04546.13 KKF92731.1 - 9.3 6.1 10.9 15 5.4 10.9 1.6 1 1 0 1 1 1 0 Sigma-70, non-essential region RraA-like PF03737.15 KKF92732.1 - 3.5e-29 101.9 0.0 4.5e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Drf_GBD PF06371.13 KKF92733.1 - 1.5e-08 34.4 2.7 0.00043 19.9 0.6 2.2 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Suc_Fer-like PF06999.12 KKF92734.1 - 2.8e-69 232.9 0.0 3.3e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Acyltransferase PF01553.21 KKF92735.1 - 6.9e-10 38.7 0.0 4.2e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase DUF3678 PF12435.8 KKF92735.1 - 0.0042 16.4 1.1 0.16 11.4 1.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3678) DUF4713 PF15831.5 KKF92735.1 - 0.15 12.5 0.2 0.39 11.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) BRAP2 PF07576.12 KKF92736.1 - 3.1e-10 40.2 0.0 5.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 APG17 PF04108.12 KKF92736.1 - 0.0024 17.1 13.4 0.0031 16.7 13.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 ADIP PF11559.8 KKF92736.1 - 0.0039 17.3 12.7 0.0039 17.3 12.7 2.3 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding DUF4164 PF13747.6 KKF92736.1 - 0.0053 17.0 11.9 0.03 14.6 7.6 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) FAM76 PF16046.5 KKF92736.1 - 0.0053 16.2 16.4 0.007 15.8 16.4 1.1 1 0 0 1 1 1 1 FAM76 protein Spc7 PF08317.11 KKF92736.1 - 0.0063 15.4 17.6 0.0091 14.9 17.6 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein YabA PF06156.13 KKF92736.1 - 0.013 16.1 12.3 0.13 12.9 2.2 2.5 2 0 0 2 2 2 0 Initiation control protein YabA MAD PF05557.13 KKF92736.1 - 0.019 13.3 22.3 0.025 13.0 22.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein HAUS-augmin3 PF14932.6 KKF92736.1 - 0.028 14.0 19.4 0.1 12.2 11.3 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Phage_GP20 PF06810.11 KKF92736.1 - 0.037 13.8 15.4 0.081 12.7 15.3 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.9 KKF92736.1 - 0.04 13.9 21.5 0.03 14.4 15.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KKF92736.1 - 0.051 13.6 9.4 0.16 12.0 1.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 KKF92736.1 - 0.059 12.7 18.8 0.097 12.0 5.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MttA_Hcf106 PF02416.16 KKF92736.1 - 0.13 11.6 0.1 0.45 9.9 0.1 2.0 1 0 0 1 1 1 0 mttA/Hcf106 family DUF3890 PF13029.6 KKF92736.1 - 0.15 12.5 0.2 0.15 12.5 0.2 2.1 2 1 0 2 2 1 0 Domain of unknown function (DUF3890) Seryl_tRNA_N PF02403.22 KKF92736.1 - 0.16 12.2 16.9 1.2 9.3 5.1 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Trehalase PF01204.18 KKF92736.1 - 0.18 10.6 9.7 0.037 12.8 6.0 1.6 1 1 1 2 2 2 0 Trehalase FlaC_arch PF05377.11 KKF92736.1 - 0.26 11.7 3.7 5.5 7.5 0.2 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 KKF92736.1 - 0.48 10.7 6.3 1.5 9.1 0.3 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper Nup54_57_C PF18570.1 KKF92736.1 - 0.62 9.7 4.9 0.48 10.1 1.0 2.4 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Rootletin PF15035.6 KKF92736.1 - 0.8 9.7 18.8 1.5 8.8 18.7 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Zein-binding PF04576.15 KKF92736.1 - 1.2 9.4 16.7 0.063 13.6 10.7 1.9 2 0 0 2 2 2 0 Zein-binding FAA_hydro_N_2 PF18288.1 KKF92736.1 - 1.4 9.4 6.0 1.6 9.2 0.7 2.5 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 FUSC PF04632.12 KKF92736.1 - 1.4 7.4 6.4 1.7 7.1 6.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fzo_mitofusin PF04799.13 KKF92736.1 - 1.5 8.3 11.1 0.87 9.1 3.2 2.2 1 1 1 2 2 2 0 fzo-like conserved region DivIC PF04977.15 KKF92736.1 - 2.4 8.0 9.2 5 7.0 1.9 2.8 1 1 2 3 3 3 0 Septum formation initiator FliD_N PF02465.18 KKF92736.1 - 2.5 8.8 13.3 1.4 9.6 0.6 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4200 PF13863.6 KKF92736.1 - 2.6 8.5 20.1 2.1 8.8 5.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) GldM_N PF12081.8 KKF92736.1 - 3 7.9 17.2 5.8 7.0 8.8 2.2 1 1 1 2 2 2 0 GldM N-terminal domain Jnk-SapK_ap_N PF09744.9 KKF92736.1 - 4.8 7.4 22.4 0.29 11.4 14.3 2.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 KKF92736.1 - 8 5.7 17.7 7 5.9 16.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KKF92736.1 - 8.7 6.5 14.1 2.4 8.4 7.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ubiquitin PF00240.23 KKF92737.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KKF92737.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KKF92737.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KKF92737.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KKF92737.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KKF92737.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KKF92737.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KKF92737.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KKF92737.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 KKF92737.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 KKF92737.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 KKF92737.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 KKF92737.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 KKF92737.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KKF92737.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KKF92737.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 KKF92737.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 KKF92737.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 KKF92737.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 KKF92737.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 KKF92737.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KKF92737.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 KKF92737.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 KKF92737.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 KKF92737.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 KKF92737.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 KKF92737.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Zn_clus PF00172.18 KKF92738.1 - 0.0039 17.3 7.7 0.008 16.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sin3a_C PF16879.5 KKF92738.1 - 0.034 13.9 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein Aldedh PF00171.22 KKF92740.1 - 7.4e-142 473.1 0.1 9.3e-142 472.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KKF92740.1 - 0.007 15.8 0.1 0.54 9.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) RRM_1 PF00076.22 KKF92742.1 - 4.9e-09 35.9 0.0 8.3e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKF92742.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GreA_GreB_N PF03449.15 KKF92743.1 - 0.0046 17.1 4.5 0.024 14.8 2.3 2.4 2 0 0 2 2 2 1 Transcription elongation factor, N-terminal DUF2046 PF09755.9 KKF92743.1 - 0.11 11.7 0.1 0.11 11.7 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Pox_A_type_inc PF04508.12 KKF92743.1 - 0.4 10.6 3.0 0.91 9.5 3.0 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat WSC PF01822.19 KKF92744.1 - 1.2e-45 153.6 66.4 3.9e-15 55.8 13.4 4.1 4 0 0 4 4 4 4 WSC domain PI-PLC-X PF00388.19 KKF92747.1 - 7.9e-07 28.8 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Rep_fac_C PF08542.11 KKF92747.1 - 0.052 14.0 0.0 0.092 13.2 0.0 1.3 1 0 0 1 1 1 0 Replication factor C C-terminal domain Vps35 PF03635.17 KKF92748.1 - 1.5e-302 1005.7 0.4 1.8e-302 1005.4 0.4 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TFR_dimer PF04253.15 KKF92749.1 - 3e-23 82.2 0.0 5.7e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KKF92749.1 - 1.4e-14 54.3 0.0 2.3e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KKF92749.1 - 4.3e-10 39.5 0.0 9.1e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 PA domain MRP-L28 PF09812.9 KKF92750.1 - 0.00029 21.0 1.5 0.00059 20.0 1.5 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.22 KKF92751.1 - 1.7e-45 154.5 0.0 2e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF92751.1 - 1.8e-19 70.2 0.0 2.6e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF92751.1 - 6.6e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKF92751.1 - 0.016 14.6 0.0 0.033 13.6 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KKF92751.1 - 0.058 12.9 0.0 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KKF92751.1 - 0.095 12.5 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KKF92751.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region HEAT_EZ PF13513.6 KKF92752.1 - 1.2e-31 108.7 8.6 1.1e-13 51.3 0.0 9.9 9 1 1 10 10 10 3 HEAT-like repeat HEAT PF02985.22 KKF92752.1 - 7.3e-20 69.4 14.0 1.9e-06 27.6 0.0 9.8 12 0 0 12 12 10 4 HEAT repeat HEAT_2 PF13646.6 KKF92752.1 - 2.7e-17 62.9 0.2 4.7e-05 23.7 0.0 6.5 5 2 2 7 7 7 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KKF92752.1 - 4e-09 37.0 0.4 0.34 11.5 0.0 6.2 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KKF92752.1 - 9.9e-08 32.2 0.3 0.019 15.0 0.0 4.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 KKF92752.1 - 4.6e-07 29.7 0.4 6.1e-05 22.9 0.0 4.5 4 1 0 4 4 4 1 Importin-beta N-terminal domain MMS19_C PF12460.8 KKF92752.1 - 2.3e-05 23.7 2.7 3 6.8 0.0 4.9 4 1 0 5 5 5 3 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KKF92752.1 - 0.00011 21.8 0.7 15 5.0 0.0 5.9 5 1 1 6 6 6 0 CLASP N terminal DUF3437 PF11919.8 KKF92752.1 - 0.0052 16.7 0.0 0.14 12.1 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) RIX1 PF08167.12 KKF92752.1 - 0.0052 16.5 0.1 5.1 6.8 0.0 4.5 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 KKF92752.1 - 0.047 13.9 0.1 3.2 8.0 0.0 2.9 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 KKF92752.1 - 0.058 12.9 0.1 43 3.5 0.0 4.0 3 1 0 3 3 3 0 Tti2 family TAF6_C PF07571.13 KKF92752.1 - 0.17 12.2 0.1 65 4.0 0.0 4.3 2 2 2 4 4 4 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 KKF92752.1 - 0.45 10.6 14.0 17 5.7 0.1 6.7 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat PAC4 PF16093.5 KKF92753.1 - 6.9e-17 61.4 0.3 1.2e-16 60.7 0.3 1.4 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 N2227 PF07942.12 KKF92754.1 - 2.1e-98 328.9 0.0 2.5e-98 328.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KKF92754.1 - 0.0029 17.5 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF92754.1 - 0.003 18.2 0.0 0.017 15.7 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF92754.1 - 0.0038 17.9 0.0 0.013 16.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF92754.1 - 0.17 11.7 0.0 0.38 10.5 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain adh_short_C2 PF13561.6 KKF92755.1 - 3.6e-45 154.3 1.2 4.8e-45 153.9 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKF92755.1 - 1.2e-43 148.9 0.6 1.8e-43 148.3 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKF92755.1 - 4.7e-11 42.9 0.2 7.5e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 KR domain FAD_binding_1 PF00667.20 KKF92756.1 - 1.5e-44 152.2 0.0 4e-44 150.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KKF92756.1 - 8.1e-09 36.1 0.0 1.9e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain SfLAP PF11139.8 KKF92756.1 - 0.071 12.5 0.4 0.12 11.8 0.4 1.3 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein zf-AN1 PF01428.16 KKF92757.1 - 2.4e-22 78.8 22.3 4.1e-11 42.9 9.4 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 KKF92757.1 - 0.002 18.3 13.0 0.011 16.0 2.6 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Sof1 PF04158.14 KKF92757.1 - 0.063 13.5 0.6 0.13 12.5 0.6 1.5 1 0 0 1 1 1 0 Sof1-like domain Transp_Tc5_C PF04236.15 KKF92757.1 - 2.4 8.6 14.3 0.26 11.7 4.0 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain MTP18 PF10558.9 KKF92758.1 - 2.8e-80 268.2 0.1 3.6e-80 267.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) VCBS PF13517.6 KKF92759.1 - 2.5e-32 111.2 26.2 4e-12 46.5 3.4 6.9 4 1 3 7 7 7 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KKF92759.1 - 1e-09 39.1 0.1 3.1e-09 37.5 0.1 1.9 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 KKF92759.1 - 4.5e-09 36.3 32.4 0.014 15.5 0.5 7.6 7 0 0 7 7 7 6 FG-GAP repeat TcdB_toxin_midN PF12256.8 KKF92759.1 - 1.4e-08 34.3 5.7 1.2 8.5 0.0 6.7 4 2 3 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.22 KKF92759.1 - 0.0016 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Dockerin_1 PF00404.18 KKF92759.1 - 0.016 15.4 11.0 0.32 11.2 0.6 5.1 4 1 1 5 5 5 0 Dockerin type I domain EF-hand_1 PF00036.32 KKF92759.1 - 4.8 7.0 17.8 6 6.7 0.1 5.6 6 0 0 6 6 6 0 EF hand ATP19 PF11022.8 KKF92760.1 - 1.2e-27 96.0 0.0 1.3e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K HTH_Tnp_Tc5 PF03221.16 KKF92761.1 - 2.7e-17 62.6 1.1 3.5e-16 59.0 0.3 2.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 KKF92761.1 - 5.7e-15 54.8 2.0 5.7e-15 54.8 2.0 3.2 2 1 0 2 2 2 1 Fission yeast centromere protein N-terminal domain DUF674 PF05056.12 KKF92761.1 - 0.0055 15.6 2.0 0.012 14.5 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF674) TFIIA PF03153.13 KKF92761.1 - 0.012 15.6 58.4 0.03 14.3 42.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MMM1 PF10296.9 KKF92761.1 - 0.035 13.2 0.0 0.035 13.2 0.0 2.7 3 0 0 3 3 3 0 Maintenance of mitochondrial morphology protein 1 PmbA_TldD PF01523.16 KKF92761.1 - 0.078 12.8 1.2 6.8 6.4 0.3 2.2 2 0 0 2 2 2 0 Putative modulator of DNA gyrase SH3_1 PF00018.28 KKF92762.1 - 2.9e-27 94.0 0.0 1.1e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KKF92762.1 - 2.5e-16 59.3 0.0 4.4e-08 32.9 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KKF92762.1 - 1.3e-14 54.2 0.1 1.3e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 PX domain SH3_2 PF07653.17 KKF92762.1 - 1.3e-10 40.8 0.0 1.7e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KKF92762.1 - 4.1e-07 29.8 0.1 6.9e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 PB1 domain SAC3_GANP PF03399.16 KKF92763.1 - 2.8e-22 79.5 0.1 5e-11 42.5 0.0 2.2 1 1 1 2 2 2 2 SAC3/GANP family EAP30 PF04157.16 KKF92764.1 - 1.8e-41 142.0 0.0 2.1e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family TFIIA PF03153.13 KKF92765.1 - 5.9 6.8 17.0 8.8 6.2 0.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Mito_carr PF00153.27 KKF92766.1 - 1.7e-21 75.9 2.7 3.4e-10 39.7 0.1 3.3 2 2 0 2 2 2 2 Mitochondrial carrier protein Sugar_tr PF00083.24 KKF92767.1 - 1.7e-104 350.2 17.0 2e-104 350.0 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF92767.1 - 1.1e-27 96.9 28.9 1.8e-21 76.5 1.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKF92767.1 - 2.8e-11 42.6 15.8 4.6e-06 25.5 2.4 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_5 PF05631.14 KKF92767.1 - 0.00032 19.8 1.6 0.00032 19.8 1.6 2.0 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Peptidase_A24 PF01478.18 KKF92767.1 - 0.58 10.6 0.1 0.58 10.6 0.1 3.1 4 0 0 4 4 4 0 Type IV leader peptidase family TB2_DP1_HVA22 PF03134.19 KKF92767.1 - 2.7 8.0 7.0 0.47 10.4 2.3 2.2 2 0 0 2 2 2 0 TB2/DP1, HVA22 family STI1 PF17830.1 KKF92768.1 - 9.8e-36 121.5 11.1 4.6e-19 68.1 0.3 2.9 3 0 0 3 3 2 2 STI1 domain TPR_1 PF00515.28 KKF92768.1 - 1e-34 116.9 15.0 1.9e-05 24.3 0.2 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 KKF92768.1 - 5.6e-25 85.4 16.0 0.024 14.7 0.1 9.4 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 KKF92768.1 - 1.3e-14 53.1 13.2 0.00061 19.8 0.7 7.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKF92768.1 - 9.8e-12 44.4 14.8 0.1 12.3 1.1 6.7 6 2 2 8 8 8 4 TPR repeat TPR_9 PF13371.6 KKF92768.1 - 2.5e-09 37.2 0.0 0.013 15.6 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKF92768.1 - 3.6e-09 36.8 4.6 1.2e-05 25.5 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKF92768.1 - 4.1e-09 36.9 2.8 0.0091 16.6 0.0 5.2 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKF92768.1 - 1.2e-07 31.2 0.8 0.073 13.1 0.0 5.2 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKF92768.1 - 6.9e-07 29.6 6.3 14 6.8 0.0 7.6 6 2 2 8 8 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKF92768.1 - 1.9e-05 25.1 7.7 2.8 8.5 0.0 6.1 5 2 1 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKF92768.1 - 0.0001 22.4 3.4 31 5.3 0.0 6.5 6 1 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKF92768.1 - 0.0046 17.0 1.3 4.8 7.3 0.0 4.0 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KKF92768.1 - 0.0057 16.5 5.8 3.1 7.8 0.0 5.5 4 2 2 6 6 6 1 Tetratricopeptide repeat DUF3391 PF11871.8 KKF92768.1 - 0.063 13.8 0.4 0.063 13.8 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) TPR_6 PF13174.6 KKF92768.1 - 0.1 13.3 9.1 8.6 7.2 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 KKF92768.1 - 0.14 12.2 4.7 6.2 7.0 0.2 5.1 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 KKF92768.1 - 0.93 9.8 4.9 3.2 8.0 1.9 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 KKF92768.1 - 1.9 8.2 6.5 2.6 7.7 0.3 3.2 2 2 0 3 3 3 0 26S proteasome subunit RPN7 MIP PF00230.20 KKF92769.1 - 2.7e-44 151.6 14.9 3.3e-44 151.3 14.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Fungal_trans PF04082.18 KKF92770.1 - 9.2e-15 54.4 0.1 9.2e-15 54.4 0.1 2.1 2 1 0 2 2 1 1 Fungal specific transcription factor domain DDHD PF02862.17 KKF92770.1 - 0.0047 17.1 13.7 0.0086 16.3 13.7 1.4 1 0 0 1 1 1 1 DDHD domain RR_TM4-6 PF06459.12 KKF92770.1 - 0.0073 16.2 20.6 0.013 15.4 20.6 1.3 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Sin_N PF04801.13 KKF92770.1 - 0.0081 15.4 30.5 0.014 14.7 30.5 1.3 1 0 0 1 1 1 1 Sin-like protein conserved region CDC45 PF02724.14 KKF92770.1 - 0.036 12.4 13.9 0.056 11.7 13.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CCSAP PF15748.5 KKF92770.1 - 0.044 14.0 26.2 0.029 14.6 23.1 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SpoIIP PF07454.11 KKF92770.1 - 0.045 13.2 21.1 0.083 12.3 21.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AIF_C PF14721.6 KKF92770.1 - 0.047 14.1 14.2 0.11 12.9 14.2 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EPL1 PF10513.9 KKF92770.1 - 0.058 13.8 18.0 0.14 12.5 18.0 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like CPSF100_C PF13299.6 KKF92770.1 - 0.072 13.3 13.2 0.14 12.3 13.2 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TCP PF03634.13 KKF92770.1 - 0.085 13.4 18.9 0.18 12.4 18.9 1.5 1 0 0 1 1 1 0 TCP family transcription factor Tim54 PF11711.8 KKF92770.1 - 0.099 11.4 19.2 0.18 10.6 19.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.12 KKF92770.1 - 0.14 11.1 27.7 0.23 10.4 27.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 KKF92770.1 - 0.16 10.7 26.8 0.29 9.9 26.8 1.4 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 KKF92770.1 - 0.25 10.3 21.1 0.41 9.6 21.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 KKF92770.1 - 0.27 10.8 19.0 0.026 14.2 14.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4407 PF14362.6 KKF92770.1 - 0.37 10.1 20.9 0.7 9.2 20.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF913 PF06025.12 KKF92770.1 - 0.43 9.5 12.6 0.67 8.9 12.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Lin-8 PF03353.15 KKF92770.1 - 0.5 9.9 25.7 0.93 9.0 25.7 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 KKF92770.1 - 0.55 9.4 9.3 1.1 8.4 9.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Afi1 PF07792.12 KKF92770.1 - 0.65 10.5 19.9 1.5 9.3 19.9 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EOS1 PF12326.8 KKF92770.1 - 0.71 9.8 8.8 1.9 8.4 8.8 1.8 1 0 0 1 1 1 0 N-glycosylation protein F-protein PF00469.20 KKF92770.1 - 0.72 9.4 16.9 1.4 8.5 16.9 1.5 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef ASD2 PF08687.11 KKF92770.1 - 0.77 9.3 25.2 1.6 8.2 25.2 1.5 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Ndc1_Nup PF09531.10 KKF92770.1 - 1 8.0 24.1 1.6 7.3 24.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LAP1C PF05609.12 KKF92770.1 - 1.2 8.1 21.8 2.2 7.3 21.8 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TRAP_alpha PF03896.16 KKF92770.1 - 1.4 8.1 11.0 26 3.9 11.4 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Plasmodium_Vir PF05795.11 KKF92770.1 - 1.5 8.2 8.4 2.4 7.5 8.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.16 KKF92770.1 - 1.6 8.8 18.6 3.3 7.7 18.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 KKF92770.1 - 1.6 8.7 17.0 3.9 7.4 17.0 1.6 1 0 0 1 1 1 0 Protein Family FAM60A NARP1 PF12569.8 KKF92770.1 - 1.7 7.4 23.6 0.62 8.9 20.9 1.5 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF4746 PF15928.5 KKF92770.1 - 1.8 7.9 17.7 3.2 7.1 17.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Band_3_cyto PF07565.13 KKF92770.1 - 1.9 8.3 20.1 3.6 7.3 20.1 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Baculo_PP31 PF05311.11 KKF92770.1 - 2.2 7.7 17.5 4.1 6.8 17.5 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF1387 PF07139.11 KKF92770.1 - 2.6 7.7 21.9 4.9 6.8 21.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Serinc PF03348.15 KKF92770.1 - 2.9 6.7 11.9 5.7 5.7 11.9 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) MDM10 PF12519.8 KKF92770.1 - 3.3 6.5 18.8 5.3 5.8 18.8 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Paramyxo_ncap PF00973.19 KKF92770.1 - 3.4 6.5 15.3 5 5.9 15.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein GREB1 PF15782.5 KKF92770.1 - 3.5 4.6 24.7 4.7 4.2 24.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Gti1_Pac2 PF09729.9 KKF92770.1 - 3.5 7.7 21.2 7.7 6.6 21.2 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Membralin PF09746.9 KKF92770.1 - 3.7 6.5 15.7 6.4 5.7 15.7 1.3 1 0 0 1 1 1 0 Tumour-associated protein DUF4175 PF13779.6 KKF92770.1 - 3.7 5.3 54.2 5.7 4.7 54.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ABC2_membrane_2 PF12679.7 KKF92770.1 - 4.1 6.6 6.0 9.8 5.4 6.0 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein LMBR1 PF04791.16 KKF92770.1 - 4.2 6.2 11.7 6.8 5.5 11.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein MAJIN PF15077.6 KKF92770.1 - 6.2 6.5 16.6 12 5.6 16.6 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Peptidase_S64 PF08192.11 KKF92770.1 - 9.2 4.6 20.2 16 3.8 20.2 1.3 1 0 0 1 1 1 0 Peptidase family S64 UvdE PF03851.14 KKF92771.1 - 2.7e-100 335.2 0.0 3.2e-100 334.9 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF5323 PF17257.2 KKF92771.1 - 1.3 8.9 3.9 0.29 11.0 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5323) Ribosomal_S21e PF01249.18 KKF92772.1 - 2.9e-41 139.4 0.2 3.3e-41 139.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e WD40 PF00400.32 KKF92773.1 - 1.8e-86 281.8 34.7 1.2e-11 44.9 0.3 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92773.1 - 6.8e-36 122.4 15.7 0.00024 21.3 0.1 8.5 2 1 7 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KKF92773.1 - 1.9e-17 63.7 0.0 2.9e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KKF92773.1 - 7e-14 51.5 13.6 0.0071 15.3 2.0 7.2 1 1 5 6 6 6 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KKF92773.1 - 4.5e-10 39.2 0.0 22 5.1 0.0 7.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KKF92773.1 - 1.8e-08 33.3 6.2 0.03 12.9 0.2 4.1 1 1 4 5 5 5 5 Cytochrome D1 heme domain Arg_repressor_C PF02863.18 KKF92773.1 - 3.6e-06 26.7 3.5 6.4 6.7 0.0 7.1 7 1 1 8 8 8 1 Arginine repressor, C-terminal domain BLUF PF04940.12 KKF92773.1 - 5.6e-06 26.4 0.0 58 3.9 0.0 6.4 7 0 0 7 7 6 0 Sensors of blue-light using FAD Robl_LC7 PF03259.17 KKF92773.1 - 1.2e-05 25.0 3.5 3.7 7.4 0.0 6.1 2 2 5 7 7 7 1 Roadblock/LC7 domain WD40_like PF17005.5 KKF92773.1 - 1.7e-05 24.3 0.6 8.4 5.6 0.0 5.1 1 1 4 6 6 6 1 WD40-like domain Germane PF10646.9 KKF92773.1 - 0.00012 22.8 2.5 52 4.7 0.2 5.3 4 2 0 5 5 5 0 Sporulation and spore germination POT1 PF02765.17 KKF92773.1 - 0.00018 21.3 1.0 9.5 6.1 0.1 4.4 2 1 1 4 4 4 1 Telomeric single stranded DNA binding POT1/CDC13 AAA_19 PF13245.6 KKF92773.1 - 0.0042 17.4 0.0 0.0087 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKF92773.1 - 0.0087 16.5 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KKF92773.1 - 0.041 13.1 0.0 0.1 11.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KKF92773.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KKF92773.1 - 0.076 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ykof PF07615.11 KKF92773.1 - 0.21 12.1 1.3 18 5.9 0.0 3.8 4 1 0 4 4 4 0 YKOF-related Family TORC_N PF12884.7 KKF92775.1 - 0.039 14.7 0.1 0.066 14.0 0.1 1.4 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus TPR_22 PF18833.1 KKF92775.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat BOP1NT PF08145.12 KKF92777.1 - 1.8e-106 355.8 7.5 2.5e-106 355.4 7.5 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KKF92777.1 - 3e-19 69.0 5.4 3.9e-07 30.6 0.1 6.0 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92777.1 - 9.8e-05 22.6 0.0 0.022 15.1 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Zn_clus PF00172.18 KKF92778.1 - 4.2e-07 30.0 7.3 8.6e-07 29.0 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IU_nuc_hydro PF01156.19 KKF92780.1 - 4.4e-76 256.4 0.0 5.4e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.13 KKF92781.1 - 2.3e-05 24.1 6.1 2.3e-05 24.1 6.1 2.8 3 1 0 3 3 3 1 RED-like protein N-terminal region DUF5643 PF18705.1 KKF92781.1 - 0.43 10.6 1.7 0.52 10.3 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5643) IMS PF00817.20 KKF92782.1 - 2.6e-41 141.1 0.0 6e-41 139.9 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KKF92782.1 - 1.8e-15 57.6 0.1 1.3e-14 54.9 0.0 2.5 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KKF92782.1 - 2.2e-06 28.0 0.0 7.7e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain mCpol PF18182.1 KKF92782.1 - 0.0012 19.1 0.0 0.0031 17.8 0.0 1.7 1 0 0 1 1 1 1 minimal CRISPR polymerase domain HHH_5 PF14520.6 KKF92782.1 - 0.013 16.1 0.0 0.037 14.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain PTCB-BRCT PF12738.7 KKF92782.1 - 0.085 12.8 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain ACT_7 PF13840.6 KKF92782.1 - 0.12 12.2 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 ACT domain REV1_C PF16727.5 KKF92783.1 - 4.4e-22 78.3 0.6 5.9e-22 77.9 0.6 1.2 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain FAR1 PF03101.15 KKF92784.1 - 0.0024 18.5 0.2 0.0047 17.6 0.2 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Phage_tail_3 PF08813.11 KKF92784.1 - 0.0029 17.2 0.1 1.7 8.3 0.0 2.2 2 0 0 2 2 2 2 Phage tail tube protein, TTP bZIP_1 PF00170.21 KKF92785.1 - 2.1e-06 27.7 5.7 2.1e-06 27.7 5.7 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KKF92785.1 - 5.1e-06 26.5 8.6 5.1e-06 26.5 8.6 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KKF92785.1 - 0.00045 20.7 5.5 0.00045 20.7 5.5 1.6 1 1 1 2 2 2 1 bZIP Maf transcription factor Takusan PF04822.13 KKF92785.1 - 0.2 11.5 1.1 0.41 10.6 1.1 1.5 1 0 0 1 1 1 0 Takusan SAYSvFN PF10260.9 KKF92786.1 - 0.34 10.9 2.3 1.3 9.0 0.1 2.9 2 1 1 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) AIRC PF00731.20 KKF92787.1 - 8e-59 197.5 1.4 8e-59 197.5 1.4 2.2 3 0 0 3 3 3 1 AIR carboxylase ATP-grasp PF02222.22 KKF92787.1 - 3.7e-42 143.8 0.0 1.1e-41 142.3 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 KKF92787.1 - 6.9e-13 48.1 0.0 1.6e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KKF92787.1 - 9.7e-05 22.0 0.0 0.00036 20.1 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 KKF92787.1 - 0.00082 19.0 0.1 0.0031 17.1 0.0 2.0 2 0 0 2 2 2 1 Propionate catabolism activator Peptidase_M28 PF04389.17 KKF92788.1 - 4e-37 127.8 0.0 5.8e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KKF92788.1 - 3.3e-12 46.3 0.1 6.5e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KKF92788.1 - 0.0042 16.8 0.0 0.0087 15.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SET PF00856.28 KKF92789.1 - 0.00056 20.3 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 SET domain Aldedh PF00171.22 KKF92790.1 - 7.8e-175 581.8 1.6 9.2e-175 581.6 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease_2 PF13520.6 KKF92792.1 - 1.1e-31 110.1 24.6 1.5e-31 109.7 24.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKF92792.1 - 7.2e-16 57.8 19.1 1.4e-15 56.9 19.1 1.4 1 0 0 1 1 1 1 Amino acid permease Alpha-L-AF_C PF06964.12 KKF92792.1 - 6.1e-10 39.5 0.0 1.1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain PSII_Ycf12 PF05969.11 KKF92792.1 - 0.067 13.2 2.3 0.16 11.9 2.3 1.7 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 Metallophos PF00149.28 KKF92793.1 - 4.8e-16 59.9 0.4 8.5e-16 59.1 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKF92793.1 - 2.5e-05 24.5 0.1 0.0038 17.4 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain sCache_2 PF17200.4 KKF92794.1 - 0.06 13.2 0.2 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 Single Cache domain 2 SAPS PF04499.15 KKF92794.1 - 0.15 10.8 0.2 0.22 10.3 0.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DnaJ PF00226.31 KKF92795.1 - 1.8e-20 72.8 0.2 7.1e-20 70.9 0.2 2.1 1 0 0 1 1 1 1 DnaJ domain MBOAT PF03062.19 KKF92796.1 - 3.9e-25 89.0 17.3 5.7e-24 85.1 17.3 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Gly_transf_sug PF04488.15 KKF92797.1 - 3.8e-13 49.9 0.2 8.1e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif WD40 PF00400.32 KKF92798.1 - 1.3e-26 92.3 7.2 5.9e-12 45.9 0.2 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92798.1 - 6.2e-12 45.7 0.1 9.4e-05 22.6 0.0 4.2 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF92798.1 - 3.8e-05 22.8 0.5 0.00016 20.8 0.5 1.9 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KKF92798.1 - 0.0036 16.0 0.4 0.45 9.1 0.1 2.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 KKF92798.1 - 0.012 14.7 0.2 0.077 12.1 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) CDtoxinA PF03498.14 KKF92798.1 - 0.038 13.6 0.0 35 4.0 0.0 2.9 1 1 2 3 3 3 0 Cytolethal distending toxin A/C domain Me-amine-dh_H PF06433.11 KKF92798.1 - 0.091 11.6 0.1 6.6 5.5 0.0 2.3 1 1 1 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) WD40_like PF17005.5 KKF92798.1 - 0.15 11.4 0.1 8.7 5.6 0.0 2.9 2 1 2 4 4 4 0 WD40-like domain NACHT_N PF17100.5 KKF92799.1 - 4.1e-43 147.8 0.8 8.1e-37 127.2 0.2 2.1 1 1 1 2 2 2 2 N-terminal domain of NWD NACHT-NTPase E1-E2_ATPase PF00122.20 KKF92800.1 - 5.7e-46 156.3 0.9 5.7e-46 156.3 0.9 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KKF92800.1 - 2e-19 70.7 1.2 8.1e-18 65.5 1.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KKF92800.1 - 3.6e-08 33.7 0.0 4.7e-06 26.9 0.0 2.8 2 0 0 2 2 2 1 Heavy-metal-associated domain HAD PF12710.7 KKF92800.1 - 0.00019 21.9 0.2 0.0016 18.8 0.1 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Adenine_deam_C PF13382.6 KKF92800.1 - 0.11 11.9 0.0 0.66 9.3 0.1 2.1 2 0 0 2 2 2 0 Adenine deaminase C-terminal domain PS_Dcarbxylase PF02666.15 KKF92801.1 - 4.1e-55 186.5 0.0 6.7e-55 185.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KKF92801.1 - 1.3e-30 105.8 0.1 9e-18 64.5 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 KKF92801.1 - 0.0016 17.8 0.0 0.0066 15.9 0.0 2.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KKF92801.1 - 0.46 10.5 0.0 0.46 10.5 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain Coatomer_E PF04733.14 KKF92802.1 - 3.3e-62 210.5 8.5 3.8e-62 210.3 8.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KKF92802.1 - 4.2e-08 33.6 24.1 0.0006 20.3 2.5 4.0 3 1 0 4 4 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF92802.1 - 9.2e-06 25.8 4.3 0.066 13.4 0.2 3.5 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KKF92802.1 - 8.3e-05 22.8 19.8 0.0051 17.1 1.7 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKF92802.1 - 0.00042 20.0 2.5 0.051 13.4 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKF92802.1 - 0.0008 20.0 27.7 0.0037 18.0 3.2 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKF92802.1 - 0.0018 18.8 6.1 2.9 8.7 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKF92802.1 - 0.0018 18.2 0.6 0.0018 18.2 0.6 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKF92802.1 - 0.017 15.3 2.8 0.3 11.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKF92802.1 - 0.018 15.6 33.2 0.037 14.6 1.9 6.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKF92802.1 - 0.032 13.9 1.7 0.032 13.9 1.7 3.5 5 0 0 5 5 5 0 TPR repeat TPR_16 PF13432.6 KKF92802.1 - 0.051 14.2 25.9 0.12 13.0 3.9 4.6 2 1 4 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KKF92802.1 - 0.052 14.0 3.6 27 5.5 0.1 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Arg_tRNA_synt_N PF03485.16 KKF92802.1 - 0.16 12.5 1.3 0.29 11.8 0.3 1.9 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain TPR_9 PF13371.6 KKF92802.1 - 1.6 8.9 12.7 0.24 11.6 1.7 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Acyl_transf_1 PF00698.21 KKF92803.1 - 1.8e-19 70.4 0.0 8.2e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain Peptidase_C39_2 PF13529.6 KKF92804.1 - 0.0023 18.5 0.0 0.0047 17.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase_C39 like family PI-PLC-X PF00388.19 KKF92805.1 - 0.21 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Metallophos PF00149.28 KKF92807.1 - 9.3e-16 58.9 0.4 1.3e-15 58.5 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SAP18 PF06487.12 KKF92809.1 - 8e-30 103.9 0.0 1e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 KKF92810.1 - 7.8e-50 168.7 0.0 7.8e-50 168.7 0.0 2.1 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KKF92810.1 - 3.1e-12 45.8 7.5 6.9e-12 44.7 1.0 2.9 2 0 0 2 2 2 2 pre-mRNA processing factor 4 (PRP4) like Borrelia_P83 PF05262.11 KKF92810.1 - 5.4 5.4 15.0 7 5.0 15.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PALP PF00291.25 KKF92811.1 - 6.3e-65 219.5 0.1 1.1e-64 218.7 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KKF92811.1 - 1.2e-09 38.5 0.0 8.5e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 CBS domain Ank_2 PF12796.7 KKF92812.1 - 1.9e-45 153.3 1.5 2.9e-13 50.2 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) DHHC PF01529.20 KKF92812.1 - 9.8e-36 122.8 11.9 9.8e-36 122.8 11.9 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 KKF92812.1 - 9.4e-25 86.4 0.0 5.5e-07 29.8 0.0 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KKF92812.1 - 2.5e-24 84.6 0.1 1.5e-05 25.2 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KKF92812.1 - 9.1e-24 83.5 1.9 2.3e-07 31.2 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKF92812.1 - 2.7e-22 76.4 2.2 5.3e-07 29.4 0.1 6.2 6 0 0 6 6 6 4 Ankyrin repeat DUF3262 PF11660.8 KKF92812.1 - 0.53 10.7 6.1 0.83 10.1 0.0 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF3262) TssN PF17555.2 KKF92812.1 - 3.1 7.1 10.2 0.1 12.0 3.1 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssN ubiquitin PF00240.23 KKF92813.1 - 0.0048 16.6 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KKF92813.1 - 0.013 16.1 0.0 0.022 15.4 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DNA_binding_1 PF01035.20 KKF92814.1 - 2.9e-27 94.6 0.0 3.8e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain PP2C PF00481.21 KKF92815.1 - 1.7e-26 93.4 0.0 1e-20 74.5 0.0 2.5 3 0 0 3 3 3 2 Protein phosphatase 2C DUF3433 PF11915.8 KKF92815.1 - 6.7e-16 58.5 12.1 3.1e-11 43.6 3.5 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) KxDL PF10241.9 KKF92816.1 - 6.6e-24 84.0 0.4 8.8e-24 83.6 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein VPR PF00522.18 KKF92816.1 - 0.02 14.9 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 VPR/VPX protein Tweety PF04906.13 KKF92816.1 - 0.2 10.3 0.2 0.26 9.9 0.2 1.1 1 0 0 1 1 1 0 Tweety DEAD PF00270.29 KKF92818.1 - 1.2e-31 109.9 0.0 2.9e-31 108.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF92818.1 - 1.9e-21 76.5 0.0 3.8e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKF92818.1 - 1.7e-20 73.0 0.0 3.6e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 KKF92818.1 - 0.01 15.1 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KKF92818.1 - 0.019 15.0 0.0 0.078 13.0 0.0 1.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit FTR1 PF03239.14 KKF92819.1 - 2.2e-66 224.1 10.7 2.7e-66 223.8 10.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Bacillus_PapR PF05968.11 KKF92819.1 - 1.8 8.5 6.2 0.65 9.9 0.2 3.0 3 0 0 3 3 3 0 Bacillus PapR protein DUF4271 PF14093.6 KKF92819.1 - 2.1 8.2 9.0 0.9 9.4 2.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) Cu-oxidase_2 PF07731.14 KKF92820.1 - 5.5e-43 146.0 2.3 6.3e-42 142.6 0.6 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KKF92820.1 - 6.3e-34 117.4 0.3 6.1e-32 111.0 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KKF92820.1 - 4.6e-20 71.8 5.7 2.2e-08 34.1 0.0 4.2 5 0 0 5 5 5 3 Multicopper oxidase CDP-OH_P_transf PF01066.21 KKF92821.1 - 3.2e-13 50.2 0.9 3.2e-13 50.2 0.9 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.24 KKF92822.1 - 3e-98 327.9 0.0 3.6e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family APH PF01636.23 KKF92823.1 - 3.5e-07 30.4 0.0 7.1e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKF92823.1 - 0.003 16.6 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KKF92823.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SRP19 PF01922.17 KKF92824.1 - 4.9e-30 104.3 0.0 7.8e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Ribosomal_60s PF00428.19 KKF92824.1 - 0.15 12.7 7.5 4.1 8.0 0.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Dynactin PF12455.8 KKF92825.1 - 9.1e-104 346.7 3.3 9.1e-104 346.7 3.3 3.7 5 0 0 5 5 5 1 Dynein associated protein CCDC-167 PF15188.6 KKF92825.1 - 2 8.8 0.0 2 8.8 0.0 7.4 3 1 2 5 5 5 0 Coiled-coil domain-containing protein 167 Spore_III_AF PF09581.10 KKF92826.1 - 0.05 13.6 0.7 0.058 13.4 0.7 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Lge1 PF11488.8 KKF92826.1 - 0.086 13.0 2.1 0.67 10.2 0.5 2.3 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 PAP2_3 PF14378.6 KKF92828.1 - 4.3e-25 88.5 13.3 4.3e-25 88.5 13.3 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KKF92828.1 - 3.2e-11 43.1 3.4 3.2e-11 43.1 3.4 2.5 2 1 1 3 3 3 1 PAP2 superfamily RseC_MucC PF04246.12 KKF92828.1 - 9.3 6.2 7.3 0.36 10.8 0.2 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC GPP34 PF05719.11 KKF92829.1 - 1.3e-69 234.3 1.4 1.7e-69 234.0 1.4 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Ras PF00071.22 KKF92830.1 - 2.2e-40 137.9 0.0 2.1e-25 89.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKF92830.1 - 3.5e-11 43.4 0.0 7.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKF92830.1 - 0.0063 16.6 0.0 0.0097 16.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KKF92830.1 - 0.033 13.6 0.0 0.083 12.3 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family PRK PF00485.18 KKF92830.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AMMECR1 PF01871.17 KKF92831.1 - 1.4e-45 154.9 0.0 1.7e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Abhydrolase_3 PF07859.13 KKF92833.1 - 2.4e-46 158.2 0.3 3.3e-46 157.8 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKF92833.1 - 7.7e-10 38.2 0.0 1.6e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KKF92833.1 - 9.5e-07 29.6 5.3 1.4e-06 29.0 5.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KKF92833.1 - 0.00092 18.7 0.0 0.091 12.2 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Eno-Rase_NADH_b PF12242.8 KKF92833.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Hydrolase_4 PF12146.8 KKF92833.1 - 0.013 14.8 0.1 0.026 13.8 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KKF92833.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KKF92833.1 - 0.12 12.0 0.1 0.88 9.2 0.1 2.0 2 0 0 2 2 2 0 PGAP1-like protein AXE1 PF05448.12 KKF92833.1 - 0.21 10.2 0.0 1.2 7.7 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) SURF6 PF04935.12 KKF92834.1 - 5.2e-47 160.2 31.7 5.2e-47 160.2 31.7 3.8 2 1 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KKF92834.1 - 2.7e-16 59.9 1.9 2.7e-16 59.9 1.9 6.8 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 Pesticin PF16754.5 KKF92835.1 - 0.11 12.4 0.3 7.4 6.5 0.1 3.1 3 0 0 3 3 3 0 Bacterial toxin homologue of phage lysozyme, C-term MitMem_reg PF13012.6 KKF92837.1 - 2.1e-06 28.1 0.1 4.9e-06 26.9 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function WD40 PF00400.32 KKF92838.1 - 1.6e-25 88.8 16.7 2.9e-06 27.9 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Vps5 PF09325.10 KKF92838.1 - 9.4e-11 41.7 1.2 2.2e-10 40.5 1.2 1.5 1 0 0 1 1 1 1 Vps5 C terminal like ANAPC4_WD40 PF12894.7 KKF92838.1 - 7.3e-08 32.6 0.1 0.12 12.7 0.0 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PX PF00787.24 KKF92838.1 - 2.4e-07 30.7 0.0 5.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 PX domain Nup160 PF11715.8 KKF92838.1 - 0.014 14.1 6.5 3 6.4 0.1 4.5 2 2 2 5 5 5 0 Nucleoporin Nup120/160 TFIIA PF03153.13 KKF92838.1 - 0.45 10.5 8.7 0.027 14.5 2.8 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Striatin PF08232.12 KKF92838.1 - 1.4 9.5 5.7 0.7 10.5 0.1 2.5 2 0 0 2 2 2 0 Striatin family Seryl_tRNA_N PF02403.22 KKF92838.1 - 4.8 7.5 5.5 28 5.0 1.4 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BCIP PF13862.6 KKF92840.1 - 2.6e-64 216.8 0.0 3.5e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PCP PF02429.15 KKF92840.1 - 0.0022 18.3 1.2 0.0056 17.0 1.2 1.7 1 0 0 1 1 1 1 Peridinin-chlorophyll A binding protein CDC45 PF02724.14 KKF92841.1 - 1e-237 790.5 5.3 6.9e-237 787.8 5.3 2.9 1 1 0 1 1 1 1 CDC45-like protein EF-hand_7 PF13499.6 KKF92841.1 - 6.4e-24 84.2 7.6 2.1e-15 56.9 0.7 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KKF92841.1 - 5e-21 72.8 4.8 1.6e-05 24.4 0.1 5.4 4 1 1 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 KKF92841.1 - 8.5e-20 68.8 15.6 1.3e-06 27.5 0.1 5.3 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 KKF92841.1 - 1.7e-14 52.5 9.7 0.00073 18.9 0.0 4.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KKF92841.1 - 1.9e-12 46.8 8.3 4.6e-05 23.2 0.3 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KKF92841.1 - 2.8e-05 24.0 6.9 0.062 13.3 0.1 4.7 2 1 2 5 5 5 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KKF92841.1 - 0.013 15.8 0.5 0.058 13.7 0.1 2.4 3 0 0 3 3 3 0 EF-hand domain SPARC_Ca_bdg PF10591.9 KKF92841.1 - 0.17 12.2 1.5 8.6 6.7 0.1 3.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region BUD22 PF09073.10 KKF92841.1 - 4 6.7 33.8 0.1 11.9 15.0 2.5 3 0 0 3 3 3 0 BUD22 Aconitase PF00330.20 KKF92842.1 - 4.2e-156 520.6 0.0 6.1e-156 520.0 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKF92842.1 - 1.9e-39 135.0 0.0 3.5e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Sulfate_transp PF00916.20 KKF92843.1 - 6.5e-80 268.7 10.6 8.9e-80 268.3 10.6 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KKF92843.1 - 4.3e-16 58.6 0.0 7.6e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KKF92843.1 - 0.0078 16.5 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KKF92843.1 - 0.014 15.8 1.4 0.014 15.8 1.4 2.9 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily Thiolase_N PF00108.23 KKF92844.1 - 1.5e-67 227.7 0.1 2.1e-67 227.3 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKF92844.1 - 8.9e-41 138.4 0.2 2.2e-40 137.2 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KKF92844.1 - 0.01 15.7 0.4 0.98 9.3 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GRDB PF07355.12 KKF92844.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) DUF1304 PF06993.12 KKF92845.1 - 1.1e-40 138.1 4.0 1.3e-40 137.8 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Deltameth_res PF16020.5 KKF92845.1 - 0.6 10.0 5.0 1.6 8.7 0.1 2.6 3 0 0 3 3 3 0 Deltamethrin resistance 5_nucleotid_C PF02872.18 KKF92846.1 - 8.3e-36 123.6 0.0 1.7e-35 122.6 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KKF92846.1 - 7.2e-05 23.4 0.1 0.00012 22.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CTP_transf_1 PF01148.20 KKF92847.1 - 2.8e-78 263.3 24.1 3.6e-78 263.0 24.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.8 KKF92848.1 - 5.8e-16 58.7 0.1 1.4e-15 57.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF2059 PF09832.9 KKF92848.1 - 0.34 11.0 0.0 0.34 11.0 0.0 3.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2059) TPR_1 PF00515.28 KKF92849.1 - 1.8e-08 33.8 6.9 0.00026 20.7 0.6 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKF92849.1 - 2e-07 30.7 7.8 0.022 15.0 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKF92849.1 - 7.2e-07 28.9 14.0 0.00069 19.5 0.8 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKF92849.1 - 8.8e-07 29.5 5.6 8.8e-07 29.5 5.6 3.7 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKF92849.1 - 0.00023 21.6 10.1 0.0026 18.2 0.8 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKF92849.1 - 0.00026 21.2 13.2 0.043 14.1 1.7 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKF92849.1 - 0.0068 17.1 0.3 0.0068 17.1 0.3 5.9 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKF92849.1 - 0.034 13.8 5.7 0.47 10.2 0.3 4.0 4 1 1 5 5 5 0 TPR repeat RPN7 PF10602.9 KKF92849.1 - 0.056 13.2 0.5 0.24 11.1 0.5 2.1 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_7 PF13176.6 KKF92849.1 - 0.18 11.9 5.4 1.6 8.9 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKF92849.1 - 0.87 10.4 11.0 13 6.6 0.2 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KKF92849.1 - 4.1 7.4 8.8 1.4 8.9 0.7 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat GYF PF02213.16 KKF92850.1 - 9.5e-19 66.8 0.2 1.8e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KKF92850.1 - 0.036 13.9 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 GYF domain 2 MerR-DNA-bind PF09278.11 KKF92850.1 - 3.5 8.2 6.3 0.78 10.3 2.8 1.8 2 0 0 2 2 2 0 MerR, DNA binding AltA1 PF16541.5 KKF92851.1 - 6.6e-10 39.8 0.3 1e-09 39.2 0.3 1.3 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Importin_rep PF18773.1 KKF92851.1 - 0.0012 18.5 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Importin 13 repeat XAP5 PF04921.14 KKF92852.1 - 3.8e-87 292.3 0.0 6.6e-87 291.5 0.0 1.3 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KKF92852.1 - 0.0092 16.4 1.5 0.0092 16.4 1.5 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4604) NAD_binding_8 PF13450.6 KKF92853.1 - 7.2e-11 42.2 0.4 1.4e-10 41.2 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ion_trans PF00520.31 KKF92853.1 - 9.3e-08 31.6 15.9 3.4e-06 26.5 15.9 2.3 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KKF92853.1 - 1.1e-07 31.0 6.9 1.9e-07 30.1 6.9 1.4 1 0 0 1 1 1 1 Polycystin cation channel FAD_oxidored PF12831.7 KKF92853.1 - 4.2e-07 29.7 1.0 7e-07 28.9 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KKF92853.1 - 4.3e-06 26.3 0.0 7.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KKF92853.1 - 9.5e-06 24.9 2.2 1.5e-05 24.3 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KKF92853.1 - 0.00028 19.7 0.3 0.00047 19.0 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KKF92853.1 - 0.00033 20.0 0.8 0.00058 19.2 0.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKF92853.1 - 0.00067 19.3 3.1 0.0014 18.2 3.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKF92853.1 - 0.0033 16.7 0.9 0.0052 16.1 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKF92853.1 - 0.016 14.4 0.5 0.032 13.5 0.5 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KKF92853.1 - 0.016 14.5 0.2 0.03 13.6 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKF92853.1 - 0.044 14.3 0.6 0.044 14.3 0.6 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKF92853.1 - 0.055 12.5 0.5 0.079 12.0 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KKF92853.1 - 0.14 11.0 1.0 0.2 10.4 1.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.6 KKF92853.1 - 0.17 12.3 0.1 0.44 11.0 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 KKF92853.1 - 0.2 11.3 0.5 0.36 10.5 0.5 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ABC_tran PF00005.27 KKF92854.1 - 1.6e-46 158.2 0.1 9.1e-23 81.3 0.0 3.7 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KKF92854.1 - 5.6e-26 90.4 0.3 2.3e-25 88.4 0.3 2.2 1 0 0 1 1 1 1 Four helical bundle domain SMC_N PF02463.19 KKF92854.1 - 5.8e-17 61.9 0.6 4.9e-06 26.1 0.1 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKF92854.1 - 2e-16 60.7 0.0 0.002 18.0 0.0 4.9 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KKF92854.1 - 3.6e-09 36.7 0.1 8.1e-05 22.6 0.0 3.0 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KKF92854.1 - 5.5e-09 35.6 0.1 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KKF92854.1 - 4.2e-08 33.9 8.0 0.0015 19.1 0.1 3.3 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KKF92854.1 - 5.8e-08 33.1 0.0 0.0026 18.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 KKF92854.1 - 2.4e-07 30.8 0.0 0.002 18.2 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KKF92854.1 - 2.8e-06 27.7 0.0 0.031 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KKF92854.1 - 3e-06 27.2 0.1 0.029 14.1 0.0 3.4 4 0 0 4 4 2 2 AAA ATPase domain AAA_18 PF13238.6 KKF92854.1 - 4.6e-06 27.2 0.4 0.1 13.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 KKF92854.1 - 2.7e-05 24.3 0.1 0.0042 17.2 0.0 2.9 2 1 0 2 2 2 1 Dynamin family MeaB PF03308.16 KKF92854.1 - 3.3e-05 23.0 0.2 0.29 10.1 0.1 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KKF92854.1 - 4.2e-05 24.0 0.0 0.52 10.7 0.0 4.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKF92854.1 - 4.9e-05 23.8 0.2 0.53 10.6 0.0 3.6 4 0 0 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 KKF92854.1 - 5e-05 23.5 0.0 0.42 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 KKF92854.1 - 5.9e-05 22.8 0.1 0.048 13.4 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KKF92854.1 - 6.3e-05 23.3 0.0 0.62 10.5 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_27 PF13514.6 KKF92854.1 - 0.00012 21.7 0.0 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KKF92854.1 - 0.00012 22.2 0.7 0.38 10.8 0.0 4.2 5 0 0 5 5 4 1 Helicase HerA, central domain Rad17 PF03215.15 KKF92854.1 - 0.00024 21.1 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 KKF92854.1 - 0.00055 19.9 0.0 0.19 11.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KKF92854.1 - 0.00073 19.3 0.2 1.8 8.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KKF92854.1 - 0.0014 18.4 0.2 3 7.5 0.0 3.5 4 0 0 4 4 4 1 AAA domain G-alpha PF00503.20 KKF92854.1 - 0.0014 17.9 0.1 1.1 8.4 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit cobW PF02492.19 KKF92854.1 - 0.0029 17.2 0.2 2.8 7.5 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 KKF92854.1 - 0.0031 17.7 0.0 0.64 10.3 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 KKF92854.1 - 0.0048 16.1 0.2 0.23 10.6 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain PRK PF00485.18 KKF92854.1 - 0.0049 16.6 0.0 0.36 10.5 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 KKF92854.1 - 0.0075 16.5 0.0 9.3 6.5 0.0 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KKF92854.1 - 0.0098 15.8 0.5 2.6 7.9 0.0 3.0 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KKF92854.1 - 0.012 15.4 0.0 7.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KKF92854.1 - 0.012 15.4 0.0 0.79 9.5 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 KKF92854.1 - 0.026 14.0 0.1 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Septin PF00735.18 KKF92854.1 - 0.027 13.8 0.3 4 6.6 0.0 2.8 3 0 0 3 3 3 0 Septin IstB_IS21 PF01695.17 KKF92854.1 - 0.029 14.1 0.0 5.1 6.8 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 KKF92854.1 - 0.033 13.3 0.3 3.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Ploopntkinase3 PF18751.1 KKF92854.1 - 0.036 14.0 0.0 8.6 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Cytidylate_kin PF02224.18 KKF92854.1 - 0.049 13.4 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 KKF92854.1 - 0.051 13.0 0.1 4.2 6.7 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 KKF92854.1 - 0.065 13.1 0.1 15 5.4 0.0 2.8 2 0 0 2 2 2 0 NTPase RE_HindVP PF09519.10 KKF92854.1 - 0.079 12.0 0.2 0.14 11.2 0.2 1.3 1 0 0 1 1 1 0 HindVP restriction endonuclease Rif1_N PF12231.8 KKF92854.1 - 0.11 11.5 0.1 0.43 9.5 0.1 2.0 2 0 0 2 2 2 0 Rap1-interacting factor 1 N terminal TsaE PF02367.17 KKF92854.1 - 0.12 12.4 0.2 49 3.9 0.0 3.2 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 KKF92854.1 - 0.12 11.9 0.2 1.1 8.7 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B dNK PF01712.19 KKF92854.1 - 0.13 12.1 0.0 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase DAP3 PF10236.9 KKF92854.1 - 0.16 11.1 2.6 5.3 6.1 0.3 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_13 PF13166.6 KKF92854.1 - 2.1 6.9 8.9 2.3 6.8 0.0 3.6 5 0 0 5 5 4 0 AAA domain Glyco_hydro_15 PF00723.21 KKF92855.1 - 6.3e-96 321.9 0.7 6.4e-96 321.9 0.0 1.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KKF92855.1 - 3.5e-23 81.3 0.0 8.6e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain SART-1 PF03343.13 KKF92856.1 - 3.4e-169 564.4 65.9 4.2e-169 564.1 65.9 1.0 1 0 0 1 1 1 1 SART-1 family ACR_tran PF00873.19 KKF92856.1 - 0.52 7.9 3.4 0.71 7.4 3.4 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF3712 PF12505.8 KKF92857.1 - 0.00052 20.3 0.2 0.016 15.5 0.2 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KKF92857.1 - 0.065 13.8 0.4 8.9 6.9 0.1 3.2 3 1 0 3 3 3 0 Late embryogenesis abundant protein OTCace_N PF02729.21 KKF92859.1 - 1.2e-42 145.5 0.1 1.6e-42 145.0 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KKF92859.1 - 1.4e-42 145.4 0.0 2.5e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ACT PF01842.25 KKF92860.1 - 3.8e-15 55.3 0.1 7.2e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 ACT domain ALS_ss_C PF10369.9 KKF92860.1 - 1.2e-14 54.3 0.1 1.2e-13 51.0 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 KKF92860.1 - 2.6e-08 33.6 0.0 4.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain DUF2187 PF09953.9 KKF92860.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) KH_1 PF00013.29 KKF92861.1 - 1.4e-10 40.9 0.0 4.2e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 KH domain RskA PF10099.9 KKF92861.1 - 1.9 8.8 16.7 4.7 7.5 5.2 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Sec63 PF02889.16 KKF92862.1 - 1.3e-165 548.9 1.6 1.2e-92 309.7 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KKF92862.1 - 3.6e-51 173.4 0.2 4.2e-28 98.3 0.0 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KKF92862.1 - 1.5e-32 112.0 0.3 5.9e-32 110.2 0.3 2.1 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KKF92862.1 - 2.3e-27 96.1 0.0 3.6e-14 53.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKF92862.1 - 1.1e-10 41.8 0.0 7.9e-07 29.4 0.0 3.9 3 1 0 3 3 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KKF92862.1 - 1.1e-07 32.2 0.1 0.0086 16.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 KKF92862.1 - 3.4e-05 23.0 0.0 0.19 10.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 KKF92862.1 - 0.015 14.8 0.0 0.39 10.1 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 KKF92862.1 - 0.015 14.8 0.0 2.2 7.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 KKF92862.1 - 0.027 14.8 0.0 15 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KKF92862.1 - 0.19 11.2 6.5 3.6 7.0 0.0 3.3 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 KKF92862.1 - 6.9 6.4 6.1 34 4.1 0.0 3.5 3 1 1 4 4 4 0 AAA domain Rep_fac_C PF08542.11 KKF92863.1 - 1.7e-19 70.0 0.0 3.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KKF92863.1 - 1.3e-08 34.8 0.1 3.2e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KKF92863.1 - 4.5e-07 30.4 0.1 3.6e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 KKF92863.1 - 9e-05 22.7 0.0 0.00028 21.2 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 KKF92863.1 - 0.0046 16.7 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF1347 PF07079.11 KKF92863.1 - 0.013 14.1 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) DUF4863 PF16155.5 KKF92863.1 - 0.13 12.1 0.0 0.42 10.5 0.0 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4863) CHORD PF04968.12 KKF92864.1 - 7.4e-47 157.9 16.2 1.4e-23 83.3 6.1 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 KKF92864.1 - 6.2e-06 27.1 0.3 1.1e-05 26.4 0.3 1.4 1 0 0 1 1 1 1 CS domain Dicty_REP PF05086.12 KKF92864.1 - 0.0053 14.8 4.1 0.0074 14.3 4.1 1.3 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 KKF92864.1 - 3.1 5.8 7.1 4.6 5.2 7.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus WH2 PF02205.20 KKF92866.1 - 9e-09 34.9 1.9 9e-09 34.9 1.9 1.8 2 0 0 2 2 2 1 WH2 motif DUF5320 PF17253.2 KKF92868.1 - 7.2 7.8 7.4 1.6 9.9 2.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5320) AAA_11 PF13086.6 KKF92869.1 - 3.6e-59 200.7 0.1 8.7e-59 199.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KKF92869.1 - 1.1e-53 181.8 0.0 2e-53 181.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKF92869.1 - 1.7e-12 47.5 0.0 5.2e-11 42.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF92869.1 - 1.9e-08 34.8 0.0 7.7e-08 32.8 0.0 2.2 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 KKF92869.1 - 2.3e-07 30.8 0.0 0.52 10.0 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KKF92869.1 - 5.9e-06 25.8 0.2 8.5e-05 21.9 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KKF92869.1 - 7.5e-06 26.0 0.0 2.4e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KKF92869.1 - 8.9e-05 22.2 0.0 0.00022 20.8 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KKF92869.1 - 0.00082 19.3 0.1 0.13 12.1 0.0 2.9 3 0 0 3 3 3 1 Helicase AAA_22 PF13401.6 KKF92869.1 - 0.0017 18.6 0.0 0.058 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKF92869.1 - 0.0052 16.4 0.7 0.058 13.0 0.0 2.8 2 1 0 3 3 3 1 AAA domain T2SSE PF00437.20 KKF92869.1 - 0.0098 15.0 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KKF92869.1 - 0.0099 16.3 0.0 0.025 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 KKF92869.1 - 0.011 15.2 0.0 0.3 10.5 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein UvrD_C_2 PF13538.6 KKF92869.1 - 0.011 15.5 0.0 0.034 14.0 0.0 1.8 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.17 KKF92869.1 - 0.011 15.4 0.0 0.036 13.8 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KKF92869.1 - 0.013 15.2 0.0 0.05 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKF92869.1 - 0.015 15.3 0.1 0.67 9.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKF92869.1 - 0.017 15.3 0.3 0.092 12.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.7 KKF92869.1 - 0.018 14.0 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 KKF92869.1 - 0.026 14.9 0.5 0.11 13.0 0.0 2.3 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 KKF92869.1 - 0.043 13.8 0.0 0.16 11.9 0.1 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain TrwB_AAD_bind PF10412.9 KKF92869.1 - 0.072 12.0 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UvrD_C PF13361.6 KKF92869.1 - 0.14 11.5 0.7 2.8 7.2 0.1 2.7 2 1 0 3 3 3 0 UvrD-like helicase C-terminal domain Snf7 PF03357.21 KKF92870.1 - 6.2e-36 123.6 21.6 6.2e-36 123.6 21.6 1.6 1 1 1 2 2 2 1 Snf7 CCAP PF11105.8 KKF92870.1 - 0.0031 17.5 1.0 0.0058 16.6 1.0 1.5 1 0 0 1 1 1 1 Arthropod cardioacceleratory peptide 2a DUF908 PF06012.12 KKF92870.1 - 0.029 13.8 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) UvrD_C PF13361.6 KKF92870.1 - 0.14 11.5 5.0 0.19 11.0 5.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ist1 PF03398.14 KKF92870.1 - 0.25 11.3 7.5 0.44 10.4 7.5 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Hpt PF01627.23 KKF92870.1 - 0.35 11.2 6.0 0.2 11.9 2.5 2.3 2 1 1 3 3 3 0 Hpt domain Peptidase_S46 PF10459.9 KKF92870.1 - 1.1 7.8 7.9 1.4 7.4 7.9 1.1 1 0 0 1 1 1 0 Peptidase S46 Dynamin_N PF00350.23 KKF92871.1 - 7.3e-18 65.2 0.6 1.8e-17 63.9 0.1 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KKF92871.1 - 1.4e-10 41.3 0.1 1.8e-09 37.7 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKF92871.1 - 9.1e-07 28.6 2.2 1.7e-05 24.5 2.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 KKF92871.1 - 0.0057 16.6 0.2 0.024 14.6 0.0 2.2 2 0 0 2 2 2 1 Short coiled-coil protein Roc PF08477.13 KKF92871.1 - 0.016 15.5 0.2 1.1 9.5 0.0 3.1 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KKF92871.1 - 0.016 14.8 0.8 0.58 9.7 0.9 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KKF92871.1 - 0.021 14.8 0.0 0.057 13.4 0.0 1.7 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KKF92871.1 - 0.027 15.0 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKF92871.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF5082 PF16888.5 KKF92871.1 - 0.57 10.5 3.2 0.46 10.8 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Phosducin PF02114.16 KKF92872.1 - 3.4e-11 42.6 0.0 5.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Phosducin Nha1_C PF08619.10 KKF92873.1 - 3e-94 316.9 20.6 3.9e-94 316.5 20.6 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KKF92873.1 - 2.9e-67 227.1 19.1 3.4e-67 226.9 19.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KKF92873.1 - 0.026 14.6 0.6 0.11 12.6 0.6 2.1 1 0 0 1 1 1 0 YrhC-like protein DUF4295 PF14128.6 KKF92873.1 - 0.21 11.4 0.3 0.4 10.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) RCC1 PF00415.18 KKF92874.1 - 3.2e-29 101.3 12.3 6.6e-09 36.3 0.1 6.8 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KKF92874.1 - 2.4e-19 68.6 24.1 1.1e-06 28.2 0.0 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Crystall_2 PF09076.10 KKF92874.1 - 0.059 13.3 0.1 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 Beta/Gamma crystallin WD40 PF00400.32 KKF92875.1 - 2.4e-28 97.8 14.8 1.2e-06 29.1 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF92875.1 - 2.1e-11 43.9 0.0 0.0016 18.7 0.1 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Zn_clus PF00172.18 KKF92875.1 - 0.00021 21.4 2.6 0.00021 21.4 2.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF2A PF08662.11 KKF92875.1 - 0.00028 20.8 0.0 0.26 11.1 0.0 2.7 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KKF92875.1 - 0.0011 18.0 0.2 0.097 11.6 0.0 2.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CENP-B_dimeris PF09026.10 KKF92876.1 - 0.0039 17.5 2.3 0.0062 16.9 2.3 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.8 KKF92876.1 - 0.34 11.1 10.6 0.42 10.8 10.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleo_P87 PF07267.11 KKF92876.1 - 0.65 8.8 3.6 0.79 8.5 3.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 KKF92876.1 - 1 8.6 6.4 1.3 8.3 6.4 1.1 1 0 0 1 1 1 0 NOA36 protein PIG-L PF02585.17 KKF92877.1 - 7.4e-29 101.0 0.0 1.5e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase LSM PF01423.22 KKF92878.1 - 3.3e-14 52.3 0.2 4.7e-14 51.8 0.2 1.3 1 0 0 1 1 1 1 LSM domain RRM_3 PF08777.11 KKF92878.1 - 0.15 12.1 0.5 0.26 11.4 0.5 1.4 1 1 0 1 1 1 0 RNA binding motif Sec23_trunk PF04811.15 KKF92879.1 - 3.8e-71 239.5 0.0 5.6e-71 239.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KKF92879.1 - 3.7e-23 81.3 0.1 1.1e-22 79.7 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KKF92879.1 - 7.5e-17 61.1 4.9 1.3e-16 60.3 4.9 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 KKF92879.1 - 1.5e-16 60.9 0.0 3.1e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KKF92879.1 - 2.3e-10 40.2 0.0 4.5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 KKF92879.1 - 0.0034 18.0 0.1 1.6 9.4 0.0 2.9 3 0 0 3 3 3 1 von Willebrand factor type A domain Vps36-NZF-N PF16988.5 KKF92879.1 - 0.03 13.7 0.1 0.062 12.7 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Yip1 PF04893.17 KKF92880.1 - 0.039 13.7 0.2 0.046 13.4 0.2 1.1 1 0 0 1 1 1 0 Yip1 domain Xpo1 PF08389.12 KKF92881.1 - 5.7e-10 39.5 10.4 4.9e-06 26.7 0.2 4.1 5 0 0 5 5 5 2 Exportin 1-like protein IBN_N PF03810.19 KKF92881.1 - 4.9e-06 26.4 1.9 0.00026 20.8 0.4 4.0 4 1 0 4 4 4 1 Importin-beta N-terminal domain DUF4904 PF16247.5 KKF92881.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) HEAT PF02985.22 KKF92881.1 - 0.081 13.2 5.4 4.2 7.9 0.2 4.9 5 0 0 5 5 5 0 HEAT repeat Arm PF00514.23 KKF92881.1 - 1.4 9.1 3.6 2.1 8.5 1.2 2.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 KKF92882.1 - 5.9e-68 229.1 0.0 7.7e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF92882.1 - 5.4e-32 111.1 0.0 7.1e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKF92882.1 - 0.00039 19.9 0.3 0.00067 19.1 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKF92882.1 - 0.0015 17.6 0.4 0.0027 16.7 0.4 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KKF92882.1 - 0.0084 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KKF92882.1 - 0.026 14.5 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KKF92882.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TLD PF07534.16 KKF92883.1 - 3.3e-25 88.9 0.0 1e-13 51.7 0.0 2.2 2 0 0 2 2 2 2 TLD SNAP PF14938.6 KKF92884.1 - 3.4e-98 328.5 10.3 3.8e-98 328.4 10.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KKF92884.1 - 8.9e-06 25.9 12.1 0.096 13.0 0.0 3.6 2 2 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 KKF92884.1 - 0.00041 20.8 6.9 4.6 8.1 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat Foie-gras_1 PF11817.8 KKF92884.1 - 0.0067 16.1 1.2 0.15 11.7 1.4 2.0 1 1 1 2 2 2 1 Foie gras liver health family 1 TPR_8 PF13181.6 KKF92884.1 - 0.007 16.5 12.0 0.12 12.7 0.4 5.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKF92884.1 - 0.018 15.0 6.9 0.51 10.5 0.4 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKF92884.1 - 0.036 14.2 16.3 12 6.3 0.4 6.5 4 2 2 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 KKF92884.1 - 0.053 13.6 4.2 38 4.4 0.3 3.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KKF92884.1 - 0.23 12.4 12.9 15 6.7 0.6 5.3 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKF92884.1 - 0.25 11.3 9.3 3.1 7.8 0.2 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KKF92884.1 - 3.2 7.8 8.5 12 5.9 1.6 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.8 KKF92885.1 - 1.5e-49 168.9 0.2 2.6e-49 168.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF92885.1 - 8.2e-08 32.3 7.8 1.6e-07 31.3 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Helicase_C PF00271.31 KKF92886.1 - 3.4e-25 88.6 0.0 7e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKF92886.1 - 5.7e-25 88.1 0.0 3.8e-24 85.4 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KKF92886.1 - 0.00049 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mre11_DNA_bind PF04152.14 KKF92886.1 - 0.0033 17.8 0.1 0.048 14.0 0.0 2.6 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain S-antigen PF05756.11 KKF92886.1 - 4.4 7.7 8.6 0.62 10.5 0.7 3.1 3 0 0 3 3 3 0 S-antigen protein Pro_isomerase PF00160.21 KKF92887.1 - 1.3e-46 158.7 0.2 1.7e-46 158.4 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 KKF92888.1 - 2.6e-26 92.1 0.1 3.7e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KKF92888.1 - 0.063 12.3 0.1 0.091 11.7 0.1 1.2 1 0 0 1 1 1 0 ANTH domain Ctr PF04145.15 KKF92889.1 - 5.5e-41 140.6 0.9 8e-41 140.1 0.9 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 KKF92889.1 - 0.02 14.6 6.9 0.095 12.4 3.6 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF485 PF04341.12 KKF92889.1 - 0.86 9.6 5.6 15 5.6 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 PAP2 PF01569.21 KKF92889.1 - 3.5 7.4 10.2 46 3.8 9.6 2.1 1 1 0 1 1 1 0 PAP2 superfamily Zip PF02535.22 KKF92890.1 - 7e-36 124.1 3.0 1.1e-35 123.5 3.0 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter JAB PF01398.21 KKF92891.1 - 8.4e-35 119.3 0.0 1.8e-34 118.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KKF92891.1 - 3.3e-11 43.6 0.6 5.4e-11 42.9 0.6 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KKF92891.1 - 4.8e-08 32.8 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KKF92891.1 - 0.057 13.5 0.1 0.14 12.2 0.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) Hist_deacetyl PF00850.19 KKF92892.1 - 1.2e-81 274.6 0.1 2.6e-81 273.5 0.1 1.6 1 0 0 1 1 1 1 Histone deacetylase domain DUF3494 PF11999.8 KKF92892.1 - 0.27 10.9 3.4 0.48 10.0 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) Mt_ATP-synt_D PF05873.12 KKF92893.1 - 0.00044 20.1 0.2 0.00058 19.7 0.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) PrpR_N PF06506.11 KKF92893.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Propionate catabolism activator Peptidase_S8 PF00082.22 KKF92894.1 - 3.3e-31 108.7 13.5 5.6e-31 107.9 13.5 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KKF92894.1 - 8.2e-10 39.2 0.0 1.7e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 INCENP_ARK-bind PF03941.15 KKF92895.1 - 0.11 12.5 0.4 0.25 11.3 0.4 1.6 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region ubiquitin PF00240.23 KKF92896.1 - 4.4e-17 61.6 0.2 6.1e-17 61.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KKF92896.1 - 5.2e-06 26.2 0.0 1.4e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KKF92896.1 - 0.00038 20.2 0.1 0.00061 19.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KKF92896.1 - 0.0034 17.9 0.1 0.0058 17.2 0.1 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KKF92896.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 KKF92896.1 - 0.046 13.7 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 HOIP UBA domain pair Tubulin PF00091.25 KKF92896.1 - 0.059 13.6 0.1 18 5.4 0.3 2.5 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain DUF4249 PF14054.6 KKF92896.1 - 0.1 12.2 0.4 0.15 11.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) STI1 PF17830.1 KKF92896.1 - 0.26 11.3 11.8 0.42 10.6 2.6 2.9 3 0 0 3 3 3 0 STI1 domain Ubiquitin_2 PF14560.6 KKF92896.1 - 0.28 11.6 0.6 0.95 10.0 0.6 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain NPR2 PF06218.11 KKF92897.1 - 1.8e-106 356.6 0.3 3.5e-92 309.5 0.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 tRNA-synt_1b PF00579.25 KKF92898.1 - 1.2e-74 251.3 0.0 1.8e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KKF92898.1 - 2.1e-41 140.5 0.0 4.1e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 KKF92898.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.7 1 0 0 1 1 1 1 S4 domain CybS PF05328.12 KKF92899.1 - 3.8e-51 172.2 0.0 4.6e-51 172.0 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit TFIIA PF03153.13 KKF92902.1 - 0.00018 21.6 41.8 0.00023 21.3 41.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit LPMO_10 PF03067.15 KKF92902.1 - 0.84 10.3 16.1 1.7 9.3 16.1 1.6 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading PAT1 PF09770.9 KKF92902.1 - 2 6.6 40.8 2.6 6.2 40.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ecl1 PF12855.7 KKF92902.1 - 2.7 9.1 10.4 7.4 7.7 10.4 1.8 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF966 PF06136.13 KKF92902.1 - 2.7 7.6 20.5 3.9 7.1 20.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF572 PF04502.13 KKF92902.1 - 3.1 7.3 17.0 5.1 6.6 17.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dapper PF15268.6 KKF92902.1 - 3.1 6.6 26.4 3.9 6.2 26.4 1.1 1 0 0 1 1 1 0 Dapper DUF4045 PF13254.6 KKF92902.1 - 3.2 7.3 23.9 5 6.7 23.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GREB1 PF15782.5 KKF92902.1 - 4.7 4.2 28.5 6.4 3.8 28.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 KKF92902.1 - 4.9 5.7 16.8 6.5 5.3 16.8 1.2 1 0 0 1 1 1 0 Hamartin protein HAD_2 PF13419.6 KKF92903.1 - 7.1e-12 45.8 0.0 2.2e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKF92903.1 - 0.0014 18.9 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKF92903.1 - 0.0035 17.4 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like RRM_1 PF00076.22 KKF92904.1 - 2.4e-19 68.9 0.2 4e-19 68.2 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKF92904.1 - 2.8e-05 23.7 0.0 3.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKF92904.1 - 0.032 14.1 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Methyltransf_11 PF08241.12 KKF92905.1 - 4.9e-10 39.9 0.0 1.8e-09 38.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF92905.1 - 0.0024 18.6 0.0 0.01 16.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Lsr2 PF11774.8 KKF92905.1 - 0.058 13.5 1.0 0.14 12.3 0.2 2.0 2 0 0 2 2 2 0 Lsr2 RNB PF00773.19 KKF92906.1 - 4.9e-97 325.2 0.0 6.6e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 KKF92906.1 - 2.4e-31 107.5 0.2 6.6e-31 106.1 0.2 1.8 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KKF92906.1 - 5e-29 100.9 0.1 8.6e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KKF92906.1 - 1.3e-18 66.8 0.0 2.9e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KKF92906.1 - 2.6e-10 40.7 0.1 2.6e-10 40.7 0.1 2.5 3 0 0 3 3 3 1 PIN domain CSD2 PF17876.1 KKF92906.1 - 4.7e-06 26.7 0.0 0.04 14.1 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Dis3l2_C_term PF17877.1 KKF92906.1 - 0.013 15.8 0.0 0.062 13.6 0.0 2.2 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 KKF92906.1 - 0.14 11.9 0.0 0.44 10.3 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain GN3L_Grn1 PF08701.11 KKF92907.1 - 5.9e-24 84.0 14.0 1e-23 83.2 14.0 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KKF92907.1 - 6e-16 58.5 0.1 2.2e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKF92907.1 - 9e-08 32.2 0.0 3.1e-06 27.2 0.0 2.4 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KKF92907.1 - 1.2e-05 25.0 0.0 0.14 11.7 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KKF92907.1 - 9.9e-05 22.5 7.5 0.2 11.7 0.1 4.3 4 1 0 4 4 4 2 Dynamin family FeoB_N PF02421.18 KKF92907.1 - 0.0058 16.2 0.3 0.074 12.6 0.1 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KKF92907.1 - 0.04 12.9 0.1 0.04 12.9 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KKF92907.1 - 0.043 13.4 0.0 0.74 9.4 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KKF92907.1 - 0.046 14.1 0.1 0.046 14.1 0.1 3.1 2 2 0 2 2 2 0 AAA ATPase domain LsmAD PF06741.13 KKF92907.1 - 1.4 9.5 13.0 0.45 11.1 6.6 2.8 2 0 0 2 2 2 0 LsmAD domain HAD_2 PF13419.6 KKF92908.1 - 4.2e-19 69.3 0.0 5.8e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKF92908.1 - 4.9e-08 33.5 0.0 0.00039 20.8 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKF92908.1 - 8.2e-06 26.3 0.0 1.6e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKF92908.1 - 0.00015 21.8 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KKF92908.1 - 0.00017 21.7 0.0 0.29 11.3 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Ribosomal_S7e PF01251.18 KKF92909.1 - 2.7e-80 268.5 0.1 3.1e-80 268.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.13 KKF92910.1 - 3.1e-187 623.1 1.5 1.3e-186 621.1 1.5 1.7 1 1 0 1 1 1 1 Dynactin p62 family DUF5473 PF17567.2 KKF92910.1 - 0.062 13.6 0.6 0.15 12.3 0.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5473) Sensor PF13796.6 KKF92911.1 - 0.038 14.0 4.8 0.017 15.2 2.8 1.4 1 1 0 1 1 1 0 Putative sensor RabGAP-TBC PF00566.18 KKF92913.1 - 2e-36 125.6 1.9 4e-21 75.7 0.0 3.2 2 1 0 2 2 2 2 Rab-GTPase-TBC domain UQ_con PF00179.26 KKF92914.1 - 1.3e-43 148.0 0.0 1.5e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKF92914.1 - 1.4e-05 24.8 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KKF92914.1 - 0.002 18.0 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KKF92914.1 - 0.067 13.5 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Collagen PF01391.18 KKF92915.1 - 8.2e-06 25.5 15.2 2e-05 24.3 15.2 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TPR_17 PF13431.6 KKF92915.1 - 0.089 13.2 0.0 25 5.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKF92915.1 - 0.4 11.6 8.5 49 5.1 0.2 5.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKF92915.1 - 1.8 9.2 10.0 26 5.4 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKF92915.1 - 2.6 8.7 14.6 17 6.1 5.2 4.2 5 1 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 KKF92916.1 - 1e-150 502.2 0.0 1.3e-150 501.8 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KKF92916.1 - 2.4e-06 27.9 0.6 0.6 11.1 0.2 5.3 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKF92916.1 - 1.2e-05 25.8 1.3 0.41 11.2 0.4 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKF92916.1 - 2.7e-05 24.0 2.8 0.077 13.1 0.4 4.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKF92916.1 - 7.6e-05 22.8 2.1 0.0021 18.2 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKF92916.1 - 0.00019 21.4 0.0 0.17 12.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKF92916.1 - 0.00027 20.8 0.4 0.61 10.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 KKF92916.1 - 0.09 12.0 4.7 0.12 11.6 0.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKF92916.1 - 0.19 11.6 6.7 2.6 8.0 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKF92916.1 - 0.31 11.3 2.5 25 5.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Oxysterol_BP PF01237.18 KKF92918.1 - 4.5e-59 200.2 0.1 7e-57 192.9 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Mtr2 PF10429.9 KKF92918.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 MSL1_dimer PF16801.5 KKF92918.1 - 0.39 10.5 4.9 0.79 9.5 4.9 1.4 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 UCH PF00443.29 KKF92919.1 - 4e-37 128.1 0.0 6.7e-37 127.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKF92919.1 - 5.2e-09 36.1 1.5 1.5e-08 34.6 1.5 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FAS_I_H PF18314.1 KKF92919.1 - 0.047 13.3 0.5 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Fatty acid synthase type I helical domain SpoIIIAH PF12685.7 KKF92919.1 - 0.063 13.1 0.5 0.13 12.1 0.5 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein Hexapep PF00132.24 KKF92920.1 - 0.043 13.6 0.0 39 4.2 0.0 3.1 1 1 3 4 4 4 0 Bacterial transferase hexapeptide (six repeats) RTA1 PF04479.13 KKF92922.1 - 1.1e-64 217.9 5.4 1.1e-64 217.9 5.4 1.9 1 1 1 2 2 2 1 RTA1 like protein DUF4227 PF14004.6 KKF92922.1 - 0.42 10.6 2.1 2.3 8.3 2.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) COX2_TM PF02790.15 KKF92922.1 - 2.6 8.2 6.5 0.58 10.3 2.0 2.2 2 1 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain Rad4 PF03835.15 KKF92923.1 - 6.6e-29 100.5 0.3 8.8e-28 96.8 0.3 2.7 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KKF92923.1 - 2.3e-26 92.0 0.2 2.4e-25 88.7 0.2 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KKF92923.1 - 2.4e-20 72.1 0.6 4.5e-20 71.2 0.6 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KKF92923.1 - 3.2e-15 56.8 0.5 3.2e-15 56.8 0.5 4.0 5 2 0 5 5 5 1 Rad4 beta-hairpin domain 2 RhoGEF PF00621.20 KKF92924.1 - 5.3e-06 26.8 0.1 1.3e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 KKF92924.1 - 2.9e-05 23.9 0.0 5.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF4763 PF15960.5 KKF92924.1 - 0.58 9.4 4.9 0.12 11.6 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) MFS_1 PF07690.16 KKF92925.1 - 7.8e-43 146.7 56.3 1.3e-40 139.4 56.9 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily RVT_1 PF00078.27 KKF92926.1 - 3.6e-07 29.9 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L23eN PF03939.13 KKF92927.1 - 9.2e-25 86.6 7.7 9.2e-25 86.6 7.7 2.5 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KKF92927.1 - 1.9e-15 57.0 0.9 1.9e-15 57.0 0.9 2.1 2 0 0 2 2 2 1 Ribosomal protein L23 P2 PF07194.11 KKF92927.1 - 0.091 12.8 0.2 0.22 11.6 0.3 1.7 2 0 0 2 2 2 0 P2 response regulator binding domain zf-Tim10_DDP PF02953.15 KKF92928.1 - 2.4e-20 71.9 1.4 3e-20 71.6 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CorA PF01544.18 KKF92929.1 - 4.6e-46 157.5 0.0 8e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GARS_A PF01071.19 KKF92930.1 - 3.8e-83 278.1 0.0 8.2e-83 277.0 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KKF92930.1 - 1.8e-36 125.6 0.0 6e-36 123.9 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KKF92930.1 - 2.5e-34 117.9 0.0 8.3e-34 116.3 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KKF92930.1 - 2.8e-27 94.8 1.0 1.5e-26 92.4 0.5 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KKF92930.1 - 9.9e-15 55.0 2.6 4.3e-14 52.9 2.6 2.2 1 1 0 1 1 1 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KKF92930.1 - 0.00016 21.3 0.1 0.00031 20.3 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 KKF92930.1 - 0.00031 20.4 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KKF92930.1 - 0.038 13.2 0.0 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KKF92930.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 KKF92930.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.10 KKF92930.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain SPC12 PF06645.13 KKF92931.1 - 2.5e-27 94.7 2.4 3e-27 94.5 2.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ZYG-11_interact PF05884.12 KKF92931.1 - 0.031 13.7 0.8 0.033 13.6 0.8 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 T_cell_tran_alt PF15128.6 KKF92931.1 - 0.2 11.5 0.2 0.62 9.9 0.3 1.7 1 1 1 2 2 2 0 T-cell leukemia translocation-altered zf-rbx1 PF12678.7 KKF92932.1 - 4.9e-06 26.7 3.9 7.9e-06 26.1 3.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KKF92932.1 - 3e-05 24.0 1.5 3.7e-05 23.7 1.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Tyr-DNA_phospho PF06087.12 KKF92934.1 - 8.6e-28 97.4 0.0 2.6e-16 59.6 0.0 2.0 1 1 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase DUF3525 PF12039.8 KKF92934.1 - 0.11 11.2 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Tna_leader PF08053.11 KKF92934.1 - 0.16 11.9 0.2 0.43 10.6 0.2 1.6 1 0 0 1 1 1 0 Tryptophanase operon leader peptide Sec1 PF00995.23 KKF92935.1 - 1.1e-95 322.1 0.0 1.5e-95 321.6 0.0 1.2 1 0 0 1 1 1 1 Sec1 family GIDA PF01134.22 KKF92935.1 - 1.2e-73 248.5 0.0 4.4e-69 233.5 0.0 2.2 1 1 1 2 2 2 2 Glucose inhibited division protein A GIDA_assoc PF13932.6 KKF92935.1 - 2e-65 220.9 0.0 3.7e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 GidA associated domain MMM1 PF10296.9 KKF92936.1 - 4.2e-76 256.2 0.5 2.1e-74 250.6 0.5 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ABC_trans_aux PF03886.13 KKF92936.1 - 0.1 12.2 0.0 0.71 9.4 0.0 2.0 1 1 1 2 2 2 0 ABC-type transport auxiliary lipoprotein component LolA PF03548.15 KKF92937.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA DrsE_2 PF13686.6 KKF92938.1 - 0.066 13.1 0.9 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 DsrE/DsrF/DrsH-like family TFIID_20kDa PF03847.13 KKF92938.1 - 0.36 11.4 1.6 0.96 10.0 0.2 2.3 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A NDUFA12 PF05071.16 KKF92940.1 - 5.5e-09 36.8 0.8 1.2e-08 35.7 0.1 1.9 1 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DivIC PF04977.15 KKF92940.1 - 0.13 12.1 0.3 0.2 11.4 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator CH PF00307.31 KKF92941.1 - 3.5e-14 52.9 0.0 7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KKF92941.1 - 0.0036 17.1 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.11 KKF92941.1 - 0.11 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin Ran_BP1 PF00638.18 KKF92942.1 - 1.7e-05 25.0 2.3 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 2 RanBP1 domain YL1 PF05764.13 KKF92942.1 - 2 8.5 22.5 0.033 14.3 6.1 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Yip1 PF04893.17 KKF92943.1 - 5.6e-13 49.0 14.1 8.2e-13 48.4 14.1 1.2 1 0 0 1 1 1 1 Yip1 domain DNA_pol_B_palm PF14792.6 KKF92944.1 - 3e-32 111.2 0.0 5.9e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KKF92944.1 - 1.4e-24 86.0 0.3 2.6e-24 85.1 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KKF92944.1 - 8.6e-19 67.7 0.0 2.3e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KKF92944.1 - 1.8e-15 56.5 0.1 3.9e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.23 KKF92944.1 - 0.0099 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain BRCT_2 PF16589.5 KKF92944.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Rad60-SLD PF11976.8 KKF92945.1 - 1.8e-16 59.7 0.0 6.4e-15 54.7 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KKF92945.1 - 4.5e-05 23.1 0.0 0.0031 17.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family LSM PF01423.22 KKF92946.1 - 5.6e-20 70.8 0.2 6.2e-20 70.7 0.2 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KKF92946.1 - 0.00037 20.5 0.1 0.00042 20.4 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KKF92946.1 - 0.00039 20.5 0.1 0.00044 20.3 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Methyltransf_25 PF13649.6 KKF92947.1 - 1.9e-11 44.5 0.0 3.8e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF92947.1 - 1.8e-10 41.4 0.0 3.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF92947.1 - 1.6e-05 25.5 0.0 3.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF92947.1 - 0.00032 20.5 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF92947.1 - 0.00084 19.2 0.0 0.0019 18.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KKF92947.1 - 0.016 14.3 0.0 0.061 12.4 0.0 1.9 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 KKF92947.1 - 0.091 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.12 KKF92947.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase LRR_4 PF12799.7 KKF92948.1 - 1.1e-11 44.8 3.7 0.19 12.2 0.0 4.6 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKF92948.1 - 3.6e-08 33.1 5.3 0.013 15.3 0.9 4.2 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KKF92948.1 - 5.2e-06 26.1 0.4 22 5.4 0.0 5.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 KKF92948.1 - 2.5e-05 23.9 0.8 1.3 8.5 0.0 3.6 2 1 0 3 3 3 3 Leucine-rich repeat Aldo_ket_red PF00248.21 KKF92949.1 - 1.1e-51 175.8 0.0 2.3e-51 174.8 0.0 1.5 1 1 1 2 2 2 1 Aldo/keto reductase family VIT1 PF01988.19 KKF92949.1 - 0.00058 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 VIT family TFIIA PF03153.13 KKF92949.1 - 0.0012 18.9 10.5 0.0016 18.6 10.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NAM-associated PF14303.6 KKF92949.1 - 0.75 10.5 18.2 1.2 9.9 18.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SAPS PF04499.15 KKF92949.1 - 0.8 8.4 9.4 1.1 7.9 9.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 KKF92949.1 - 1.7 8.9 10.5 2.4 8.4 10.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family GET2 PF08690.10 KKF92949.1 - 8 6.0 11.8 11 5.5 11.8 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Glutaredoxin PF00462.24 KKF92950.1 - 4.8e-14 52.3 0.0 1e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KKF92950.1 - 0.014 15.8 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Cys_Met_Meta_PP PF01053.20 KKF92951.1 - 2.9e-140 467.1 0.0 3.4e-140 466.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KKF92951.1 - 6.8e-10 38.7 0.1 8.9e-10 38.3 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKF92951.1 - 1.9e-05 23.8 0.1 3.6e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKF92951.1 - 6.5e-05 22.4 0.4 0.00012 21.5 0.4 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KKF92951.1 - 0.022 14.0 0.1 0.041 13.2 0.1 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Fungal_trans_2 PF11951.8 KKF92952.1 - 4.1e-06 25.9 0.2 6.2e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Brix PF04427.18 KKF92953.1 - 1.5e-39 136.1 0.1 2.3e-39 135.5 0.1 1.3 1 0 0 1 1 1 1 Brix domain DUF3336 PF11815.8 KKF92953.1 - 2.1e-19 69.6 0.0 9.4e-19 67.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KKF92953.1 - 5.7e-07 29.9 0.1 1.3e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Leo1 PF04004.13 KKF92954.1 - 9.4e-30 103.6 0.2 9.4e-30 103.6 0.2 2.8 3 0 0 3 3 3 1 Leo1-like protein NBD_C PF17042.5 KKF92954.1 - 0.42 11.1 2.1 0.87 10.1 2.1 1.5 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain SMBP PF16785.5 KKF92954.1 - 0.65 10.2 5.4 1.4 9.1 5.4 1.6 1 0 0 1 1 1 0 Small metal-binding protein DUF3499 PF12005.8 KKF92954.1 - 4.9 7.8 11.6 1.2 9.8 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Mob1_phocein PF03637.17 KKF92955.1 - 3e-42 144.5 1.5 1e-41 142.8 1.5 1.7 1 1 0 1 1 1 1 Mob1/phocein family MethyTransf_Reg PF10119.9 KKF92955.1 - 0.39 11.5 3.8 0.71 10.6 1.0 2.5 3 0 0 3 3 3 0 Predicted methyltransferase regulatory domain bZIP_1 PF00170.21 KKF92956.1 - 5.4e-11 42.4 16.1 2.7e-09 37.0 13.4 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 KKF92956.1 - 8e-06 26.3 12.6 8e-06 26.3 12.6 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KKF92956.1 - 1.4e-05 25.0 13.1 1.7e-05 24.8 10.4 2.3 2 0 0 2 2 2 1 Basic region leucine zipper UPF0242 PF06785.11 KKF92956.1 - 0.31 11.1 15.0 0.7 10.0 15.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 KKF92956.1 - 0.47 9.0 6.2 0.99 7.9 6.2 1.6 1 0 0 1 1 1 0 Flagellar Assembly Protein A 5_nucleotid PF05761.14 KKF92956.1 - 0.96 8.3 8.1 1.5 7.6 8.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family AAA_13 PF13166.6 KKF92956.1 - 1.2 7.6 10.7 2.3 6.8 10.7 1.3 1 0 0 1 1 1 0 AAA domain Radial_spoke_3 PF06098.11 KKF92956.1 - 1.6 8.0 14.4 3.2 7.0 14.4 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 Sel1 PF08238.12 KKF92957.1 - 1.4e-09 38.3 0.7 0.22 12.3 0.0 4.8 5 0 0 5 5 5 4 Sel1 repeat CK_II_beta PF01214.18 KKF92958.1 - 3.7e-76 255.0 0.2 4.7e-76 254.6 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ribosomal_L5 PF00281.19 KKF92958.1 - 0.021 15.2 0.0 7.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L5 Uso1_p115_C PF04871.13 KKF92958.1 - 0.068 13.5 8.5 0.11 12.9 8.5 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-B_dimeris PF09026.10 KKF92958.1 - 0.32 11.4 4.6 0.68 10.3 4.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RIC1 PF07064.13 KKF92959.1 - 3.7e-67 226.4 2.2 4.4e-67 226.1 2.2 1.1 1 0 0 1 1 1 1 RIC1 YLP PF02757.17 KKF92959.1 - 0.2 11.7 0.7 0.9 9.7 0.7 2.1 1 0 0 1 1 1 0 YLP motif WD40 PF00400.32 KKF92960.1 - 5.8e-23 80.7 2.9 1.2e-06 29.1 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Fungal_trans PF04082.18 KKF92960.1 - 3.4e-20 72.2 0.1 5.2e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF92960.1 - 5.6e-09 36.0 8.2 9.9e-09 35.2 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC4_WD40 PF12894.7 KKF92960.1 - 4.2e-07 30.2 0.0 0.45 10.8 0.0 4.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKF92960.1 - 0.0094 14.6 0.1 0.089 11.4 0.0 2.1 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Glutaredoxin PF00462.24 KKF92961.1 - 1.3e-18 67.0 0.0 5.5e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KKF92961.1 - 7.3e-16 58.0 0.0 1.7e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KKF92961.1 - 0.0076 16.2 0.1 0.042 13.8 0.0 2.0 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 KKF92961.1 - 0.022 14.7 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family Disulph_isomer PF06491.11 KKF92961.1 - 0.048 13.8 2.6 16 5.6 1.5 3.2 2 1 1 3 3 3 0 Disulphide isomerase Shadoo PF14999.6 KKF92961.1 - 0.067 13.3 3.2 0.1 12.7 3.2 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective TBCA PF02970.16 KKF92962.1 - 1.6e-21 76.4 4.6 2.1e-21 76.0 4.6 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A THOC7 PF05615.13 KKF92963.1 - 3.9e-38 130.7 10.7 3.9e-38 130.7 10.7 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 FUSC PF04632.12 KKF92963.1 - 4.3 5.8 12.1 4.3 5.8 11.2 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family YkyA PF10368.9 KKF92963.1 - 7.4 6.2 13.6 0.45 10.2 2.7 2.6 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein PAP2 PF01569.21 KKF92965.1 - 4.2e-23 81.6 4.1 1.2e-22 80.1 1.9 2.6 2 1 0 2 2 2 1 PAP2 superfamily UNC45-central PF11701.8 KKF92966.1 - 0.16 11.9 0.8 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central PhoD PF09423.10 KKF92967.1 - 9e-08 31.5 1.6 2.5e-06 26.8 1.6 2.6 1 1 0 1 1 1 1 PhoD-like phosphatase Aldedh PF00171.22 KKF92968.1 - 3.8e-108 362.0 0.0 4.5e-108 361.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HLH PF00010.26 KKF92969.1 - 0.003 17.5 0.0 0.003 17.5 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Sporozoite_P67 PF05642.11 KKF92969.1 - 1.8 6.6 13.6 0.45 8.5 10.1 1.8 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Per1 PF04080.13 KKF92970.1 - 1.3e-106 356.1 11.0 1.5e-106 355.8 11.0 1.0 1 0 0 1 1 1 1 Per1-like family Aa_trans PF01490.18 KKF92970.1 - 0.048 12.4 1.1 0.065 11.9 0.2 1.6 1 1 0 2 2 2 0 Transmembrane amino acid transporter protein Polysacc_synt_C PF14667.6 KKF92970.1 - 5.9 7.0 7.9 24 5.0 6.0 2.4 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain eIF3_subunit PF08597.10 KKF92971.1 - 1.9e-69 234.3 21.7 2.1e-69 234.1 21.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Endonuc_Holl PF10107.9 KKF92971.1 - 0.47 10.3 5.4 0.95 9.3 0.0 2.3 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF4746 PF15928.5 KKF92971.1 - 0.96 8.8 12.2 0.22 10.9 6.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) VSG_B PF13206.6 KKF92971.1 - 2.3 7.4 24.2 1.5 8.0 12.3 2.0 1 1 0 2 2 2 0 Trypanosomal VSG domain FKBP_N PF01346.18 KKF92971.1 - 2.3 9.2 11.3 0.12 13.3 1.1 2.4 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Cupredoxin_1 PF13473.6 KKF92974.1 - 0.021 14.9 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain Peroxidase_2 PF01328.17 KKF92975.1 - 6e-41 141.0 0.0 8.1e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF382 PF04037.13 KKF92978.1 - 1e-59 200.2 0.8 2.9e-59 198.8 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 KKF92978.1 - 9.9e-20 70.2 4.1 2.1e-19 69.1 4.1 1.6 1 0 0 1 1 1 1 PSP CENP-B_dimeris PF09026.10 KKF92978.1 - 0.17 12.3 10.5 0.58 10.6 10.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KKF92978.1 - 1.6 8.0 4.8 3.5 6.8 4.8 1.5 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KKF92978.1 - 4.5 5.3 7.2 7.3 4.6 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi VEFS-Box PF09733.9 KKF92979.1 - 0.0023 17.8 0.7 0.0068 16.2 0.7 1.8 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Trypan_PARP PF05887.11 KKF92979.1 - 0.01 15.8 3.8 0.015 15.3 3.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HalOD2 PF18547.1 KKF92979.1 - 0.048 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Halobacterial output domain 2 Neisseria_TspB PF05616.13 KKF92979.1 - 2.1 6.7 5.8 3.4 6.0 5.8 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Hist_deacetyl PF00850.19 KKF92982.1 - 6.1e-80 269.0 0.0 9.9e-80 268.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 KKF92982.1 - 1.4e-73 247.2 5.3 6.8e-67 225.3 0.4 2.2 1 1 1 2 2 2 2 Arb2 domain Brix PF04427.18 KKF92983.1 - 4.9e-38 131.2 0.0 7.2e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain Ras PF00071.22 KKF92984.1 - 5.5e-55 185.4 0.4 6.9e-55 185.1 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF92984.1 - 7.4e-27 94.0 0.2 1.1e-26 93.4 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF92984.1 - 1.3e-09 37.8 0.1 1.6e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKF92984.1 - 0.00081 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SpoIIID PF12116.8 KKF92984.1 - 0.078 13.1 0.1 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D Aldo_ket_red PF00248.21 KKF92985.1 - 1.4e-47 162.3 0.0 1.7e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Meth_synt_2 PF01717.18 KKF92986.1 - 1.4e-14 54.1 0.0 6.7e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KKF92986.1 - 0.061 12.8 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain PARP PF00644.20 KKF92987.1 - 1.6e-58 197.6 0.0 4.2e-58 196.1 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KKF92987.1 - 1.2e-43 148.5 0.2 2e-43 147.8 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KKF92987.1 - 3.8e-20 71.7 0.3 8.2e-20 70.7 0.3 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KKF92987.1 - 6.9e-14 52.0 0.1 1.5e-13 50.9 0.1 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KKF92987.1 - 1e-09 38.2 0.1 2e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KKF92987.1 - 1.8e-05 25.0 0.0 5.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KKF92987.1 - 0.029 14.4 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain ABC2_membrane PF01061.24 KKF92988.1 - 9.5e-87 289.8 65.3 1.7e-45 155.0 26.2 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKF92988.1 - 3.2e-37 128.1 0.0 3.4e-17 63.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KKF92988.1 - 3.8e-33 113.2 13.4 3.6e-31 106.9 0.1 4.0 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 KKF92988.1 - 2.1e-16 60.3 0.1 5.7e-16 58.9 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KKF92988.1 - 1.2e-06 29.0 0.1 0.00039 20.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KKF92988.1 - 2.8e-06 27.9 0.0 0.00089 19.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KKF92988.1 - 5.7e-06 26.3 0.0 0.00067 19.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KKF92988.1 - 6.5e-06 26.4 0.0 0.018 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KKF92988.1 - 0.00022 21.5 0.1 0.26 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KKF92988.1 - 0.0003 20.7 0.0 0.84 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KKF92988.1 - 0.00055 19.6 0.0 0.0075 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KKF92988.1 - 0.001 18.7 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KKF92988.1 - 0.0021 18.5 0.0 0.27 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKF92988.1 - 0.0023 17.7 0.9 0.016 15.0 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KKF92988.1 - 0.0079 16.1 0.1 1.3 9.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KKF92988.1 - 0.009 16.4 0.0 2.9 8.3 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KKF92988.1 - 0.011 15.5 0.1 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KKF92988.1 - 0.014 14.9 0.0 1.4 8.3 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain TsaE PF02367.17 KKF92988.1 - 0.063 13.3 0.1 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KKF92988.1 - 0.067 12.9 0.1 6.4 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKF92988.1 - 0.068 12.4 0.0 0.68 9.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 KKF92988.1 - 0.12 12.8 0.1 0.37 11.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF2417 PF10329.9 KKF92989.1 - 2.6e-74 249.6 2.6 4.1e-74 249.0 2.6 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 KKF92989.1 - 0.093 12.4 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold SLATT_4 PF18186.1 KKF92989.1 - 0.28 10.8 6.2 8.3 6.0 0.1 2.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Sigma_M_inh PF17453.2 KKF92989.1 - 1.7 9.1 8.2 0.9 10.0 4.6 2.2 2 0 0 2 2 2 0 Sigma-M inhibitor DUF2070 PF09843.9 KKF92989.1 - 1.7 6.8 12.4 2.4 6.3 12.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CCB2_CCB4 PF11152.8 KKF92989.1 - 4.3 6.6 7.8 11 5.2 7.8 1.7 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 AAA PF00004.29 KKF92992.1 - 3e-16 60.1 0.0 3.9e-15 56.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKF92992.1 - 0.0043 17.3 1.4 0.15 12.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KKF92992.1 - 0.012 15.6 0.1 0.03 14.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKF92992.1 - 0.033 14.3 0.0 0.14 12.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKF92992.1 - 0.044 13.5 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKF92992.1 - 0.12 12.8 0.2 0.4 11.0 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 KKF92992.1 - 0.25 11.1 0.0 0.25 11.1 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 KKF92992.1 - 0.44 11.1 0.0 0.44 11.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain Methyltransf_10 PF05971.12 KKF92994.1 - 4.9e-22 78.6 0.0 7.1e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase LDB19 PF13002.7 KKF92994.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Arrestin_N terminal like BAF1_ABF1 PF04684.13 KKF92995.1 - 0.8 8.7 3.2 0.98 8.4 3.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Epimerase PF01370.21 KKF92996.1 - 3.6e-20 72.4 0.0 4.6e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKF92996.1 - 4.6e-13 48.8 0.0 6.5e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKF92996.1 - 2.4e-10 40.4 0.0 3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KKF92996.1 - 2.2e-08 33.6 0.4 2.7e-06 26.8 0.4 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KKF92996.1 - 2.3e-05 24.4 0.0 6.3e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KKF92996.1 - 0.00015 21.4 0.1 0.0043 16.7 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KKF92996.1 - 0.00017 20.8 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KKF92996.1 - 0.0046 16.9 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KKF92996.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KKF92996.1 - 0.06 12.4 0.0 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain COX14 PF14880.6 KKF92997.1 - 1.6e-10 40.7 0.4 2.4e-10 40.1 0.4 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Ribosomal_L13e PF01294.18 KKF92998.1 - 5.5e-63 212.1 2.0 8.2e-63 211.5 2.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e PAP_assoc PF03828.19 KKF93001.1 - 4.1e-13 49.3 0.0 8.7e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Nre_C PF04895.12 KKF93001.1 - 0.13 12.2 0.1 0.32 10.9 0.1 1.6 1 1 0 1 1 1 0 Archaeal Nre, C-terminal Zn_clus PF00172.18 KKF93002.1 - 1.1e-07 31.8 6.8 2.4e-07 30.7 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KKF93003.1 - 1.6e-47 161.5 1.9 2.1e-47 161.1 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF93003.1 - 7.4e-33 114.1 2.1 9.4e-33 113.7 2.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF93003.1 - 2.3e-12 47.2 0.2 3.2e-12 46.7 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KKF93003.1 - 6.3e-05 23.0 0.3 8.7e-05 22.5 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KKF93003.1 - 0.00017 21.3 0.4 0.00028 20.5 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KKF93003.1 - 0.00058 19.4 1.0 0.0067 15.9 1.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ANAPC4_WD40 PF12894.7 KKF93005.1 - 0.082 13.2 0.0 13 6.1 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain COesterase PF00135.28 KKF93006.1 - 3e-80 270.6 0.4 9.7e-58 196.3 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KKF93006.1 - 8.9e-05 22.4 0.0 0.00018 21.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKF93006.1 - 0.0087 15.6 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KKF93006.1 - 0.011 16.3 0.4 0.061 13.9 0.0 2.1 1 1 1 3 3 3 0 Alpha/beta hydrolase family zf-C2H2 PF00096.26 KKF93007.1 - 3.5e-13 49.2 11.4 8.2e-07 29.2 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKF93007.1 - 1.1e-08 35.2 8.9 0.0011 19.6 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKF93007.1 - 2.7e-08 33.8 11.7 1.9e-07 31.2 4.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KKF93007.1 - 5.6e-07 29.7 3.2 0.00025 21.3 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKF93007.1 - 3.6e-06 27.1 2.7 0.0029 17.8 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KKF93007.1 - 0.00031 20.7 7.8 0.1 12.6 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KKF93007.1 - 0.0041 16.7 2.5 0.67 9.6 0.1 2.3 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf_UBZ PF18439.1 KKF93007.1 - 0.026 14.1 1.3 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 KKF93007.1 - 0.028 14.3 2.9 0.093 12.6 0.2 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_3rep PF18868.1 KKF93007.1 - 0.073 13.8 1.8 8.4 7.1 0.2 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 KKF93007.1 - 0.11 12.5 0.8 1.8 8.7 0.1 2.2 1 1 1 2 2 2 0 CpXC protein zf-UBR PF02207.20 KKF93007.1 - 0.13 12.4 0.7 0.26 11.5 0.7 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_2 PF12756.7 KKF93007.1 - 0.14 12.5 4.0 4.9 7.5 0.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 KKF93007.1 - 0.32 10.1 1.3 1.5 7.9 1.3 1.8 1 1 0 1 1 1 0 Putative actin-like family zf-BED PF02892.15 KKF93007.1 - 0.34 11.0 4.9 0.21 11.6 1.3 2.2 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 KKF93007.1 - 4 7.6 6.8 5.1 7.3 0.4 2.8 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 KKF93007.1 - 5.1 6.9 10.7 4.6 7.1 0.0 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KKF93007.1 - 6.9 6.7 6.4 9.6 6.2 2.1 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Transthyretin PF00576.21 KKF93009.1 - 5.7e-37 126.8 0.0 1.1e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 HIUase/Transthyretin family TFIIIC_sub6 PF10419.9 KKF93009.1 - 1.1e-23 82.9 0.0 2.2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain CarboxypepD_reg PF13620.6 KKF93009.1 - 0.00025 21.2 0.1 0.00063 20.0 0.1 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 KKF93009.1 - 0.0079 16.2 0.6 0.021 14.8 0.6 1.7 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) His_biosynth PF00977.21 KKF93010.1 - 5e-46 157.0 1.1 2.7e-45 154.6 1.1 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KKF93010.1 - 1.9e-20 73.5 0.0 3.1e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KKF93010.1 - 4.9e-09 36.3 0.0 6e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KKF93010.1 - 3.4e-07 30.1 0.0 1.4e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain NMO PF03060.15 KKF93010.1 - 0.027 13.9 2.7 0.072 12.5 0.1 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase Dus PF01207.17 KKF93010.1 - 0.19 10.8 0.1 0.48 9.5 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) ODC_AZ PF02100.17 KKF93011.1 - 2.3e-37 127.5 0.2 3.2e-37 127.0 0.2 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Peptidase_M20 PF01546.28 KKF93012.1 - 8.3e-34 117.1 0.0 1.4e-33 116.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKF93012.1 - 2.3e-11 43.6 0.0 3.5e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKF93012.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 DWNN PF08783.11 KKF93013.1 - 1.9e-31 108.1 0.0 3.2e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-C3HC4_2 PF13923.6 KKF93013.1 - 0.0018 18.1 9.1 0.003 17.4 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_2 PF13696.6 KKF93013.1 - 0.0034 17.2 3.4 0.0042 16.9 2.0 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-RING_2 PF13639.6 KKF93013.1 - 0.032 14.6 8.0 0.053 13.9 8.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.6 KKF93013.1 - 0.048 13.5 1.6 0.09 12.7 1.6 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE_2 PF02318.16 KKF93013.1 - 0.096 12.9 1.1 0.2 11.9 1.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_5 PF14634.6 KKF93013.1 - 0.21 11.6 7.9 0.37 10.8 7.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 KKF93013.1 - 0.25 11.2 5.8 0.5 10.2 5.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KKF93013.1 - 0.34 10.8 8.6 0.59 10.1 8.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KKF93013.1 - 0.45 10.5 3.4 0.75 9.7 3.4 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.6 KKF93013.1 - 1.4 9.0 6.2 2.8 8.1 6.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KKF93013.1 - 1.8 8.8 8.5 3.4 7.9 8.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ArsA_ATPase PF02374.15 KKF93014.1 - 2.2e-109 365.4 0.0 2.5e-109 365.2 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 KKF93014.1 - 2.8e-12 46.8 0.0 4.5e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KKF93014.1 - 4.9e-12 46.1 0.0 6.6e-11 42.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KKF93014.1 - 6.1e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KKF93014.1 - 2.4e-05 23.9 0.2 0.00021 20.8 0.0 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KKF93014.1 - 3.4e-05 23.5 0.1 8.2e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 KKF93014.1 - 0.00012 21.8 0.1 0.0014 18.3 0.0 2.3 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KKF93014.1 - 0.048 13.2 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KKF93014.1 - 0.049 12.8 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain tRNA-synt_1e PF01406.19 KKF93015.1 - 3.1e-91 305.9 0.5 2.3e-56 191.3 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 KKF93015.1 - 2.1e-05 24.9 0.0 2.1e-05 24.9 0.0 2.5 3 0 0 3 3 3 1 DALR domain tRNA-synt_1g PF09334.11 KKF93015.1 - 0.00012 21.0 1.0 0.25 10.0 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 KKF93015.1 - 0.0065 15.4 0.0 0.023 13.6 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain LPD24 PF18839.1 KKF93015.1 - 0.076 13.3 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Large polyvalent protein associated domain 24 Gly_transf_sug PF04488.15 KKF93016.1 - 0.0006 20.4 0.6 0.0014 19.2 0.6 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif NicO PF03824.16 KKF93017.1 - 1.2e-66 224.9 8.5 1.9e-66 224.3 8.5 1.3 1 0 0 1 1 1 1 High-affinity nickel-transport protein Peptidase_C2 PF00648.21 KKF93018.1 - 2.3e-57 194.3 0.8 1.2e-55 188.7 0.8 2.4 1 1 0 1 1 1 1 Calpain family cysteine protease HIPIP PF01355.17 KKF93018.1 - 0.4 11.1 6.5 0.061 13.7 0.9 2.5 2 0 0 2 2 2 0 High potential iron-sulfur protein Fungal_trans PF04082.18 KKF93019.1 - 1.2e-07 31.0 0.1 1.9e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNase_T PF00929.24 KKF93020.1 - 0.012 16.2 0.0 0.17 12.5 0.0 2.1 1 1 0 1 1 1 0 Exonuclease Imm50 PF15594.6 KKF93020.1 - 0.12 12.6 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 50 Methyltransf_12 PF08242.12 KKF93021.1 - 5.2e-08 33.5 0.0 2.2e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF93021.1 - 4.7e-07 29.8 0.0 6.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF93021.1 - 1.1e-06 29.3 0.0 6e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF93021.1 - 2.6e-05 24.8 0.0 0.0025 18.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKF93021.1 - 3.9e-05 23.3 0.0 0.0049 16.4 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 KKF93021.1 - 0.0049 16.7 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_3_C PF01915.22 KKF93022.1 - 3.3e-50 170.9 0.0 1.6e-49 168.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKF93022.1 - 1.2e-34 120.2 0.0 2.1e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKF93022.1 - 7.9e-13 48.3 0.0 1.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ERG4_ERG24 PF01222.17 KKF93023.1 - 9.6e-145 482.6 4.4 6.6e-144 479.8 4.4 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KKF93023.1 - 0.0018 17.8 0.2 0.0043 16.6 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) AMP-binding PF00501.28 KKF93025.1 - 7.6e-63 212.6 0.4 8.4e-37 126.8 0.0 4.4 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KKF93025.1 - 1.4e-11 45.2 2.6 2.7e-11 44.3 0.0 2.6 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 KKF93025.1 - 0.00011 22.1 0.2 0.00029 20.8 0.2 1.6 1 0 0 1 1 1 1 Gas vesicle protein G PDEase_II PF02112.15 KKF93027.1 - 2.9e-53 181.2 0.1 4.6e-23 81.9 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KKF93027.1 - 0.024 14.2 0.1 0.066 12.7 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Flavin_Reduct PF01613.18 KKF93028.1 - 9.1e-16 58.3 0.0 1.3e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain NOA36 PF06524.12 KKF93029.1 - 0.044 13.1 5.6 0.038 13.3 5.6 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 KKF93029.1 - 0.092 12.6 5.4 0.1 12.5 5.4 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.6 KKF93029.1 - 0.76 10.0 7.6 0.15 12.3 4.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sugar_tr PF00083.24 KKF93031.1 - 6.6e-124 414.2 27.0 7.5e-124 414.0 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF93031.1 - 5.9e-19 68.2 34.1 5.9e-19 68.2 34.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM132D_C PF15706.5 KKF93031.1 - 0.42 10.4 1.8 0.47 10.2 0.1 1.9 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term IBN_N PF03810.19 KKF93032.1 - 1.1e-11 44.5 0.0 4.2e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 KKF93032.1 - 0.024 13.2 0.0 0.061 11.8 0.0 1.6 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus Xpo1 PF08389.12 KKF93032.1 - 0.028 14.5 0.0 0.65 10.1 0.0 3.2 2 1 0 2 2 2 0 Exportin 1-like protein HEAT PF02985.22 KKF93032.1 - 0.23 11.8 3.8 3.6 8.1 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat PAPS_reduct PF01507.19 KKF93033.1 - 5.4e-27 94.9 0.0 1.4e-24 87.1 0.0 2.7 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Sad1_UNC PF07738.13 KKF93033.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal DEAD PF00270.29 KKF93034.1 - 9.2e-47 159.1 0.4 1.7e-46 158.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF93034.1 - 2e-24 86.1 0.2 3e-22 79.1 0.0 3.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKF93034.1 - 1.6e-19 69.9 0.1 7.9e-19 67.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KKF93034.1 - 6.3e-07 29.6 0.0 6.3e-07 29.6 0.0 2.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit CRAL_TRIO PF00650.20 KKF93035.1 - 1.2e-24 86.8 0.0 1.8e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKF93035.1 - 1.6e-07 31.4 0.0 3.6e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Acid_PPase PF12689.7 KKF93036.1 - 1.8e-60 203.6 0.0 9.2e-60 201.3 0.0 1.8 1 1 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 KKF93036.1 - 0.057 13.5 0.3 0.49 10.4 0.0 2.3 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase PI-PLC-X PF00388.19 KKF93037.1 - 6.2e-07 29.1 0.0 2.4e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Mid2 PF04478.12 KKF93038.1 - 0.00034 20.5 0.0 0.0008 19.3 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Kelch_4 PF13418.6 KKF93038.1 - 0.0004 20.3 3.2 0.53 10.3 0.0 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KKF93038.1 - 0.0035 16.9 6.9 0.092 12.3 0.0 4.2 5 0 0 5 5 5 2 Kelch motif DUF347 PF03988.12 KKF93038.1 - 0.023 14.9 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) TMEM154 PF15102.6 KKF93038.1 - 0.059 13.3 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 KKF93038.1 - 0.24 11.2 0.1 0.42 10.4 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 V-SNARE_C PF12352.8 KKF93039.1 - 2e-13 50.4 0.5 2e-13 50.4 0.5 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KKF93039.1 - 2.9e-05 23.9 0.1 0.00012 21.9 0.0 2.0 2 1 1 3 3 3 1 Sec20 NUDE_C PF04880.13 KKF93039.1 - 0.0011 19.5 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region Uso1_p115_C PF04871.13 KKF93039.1 - 0.17 12.2 1.4 0.48 10.8 0.4 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region RmuC PF02646.16 KKF93039.1 - 0.28 10.3 1.9 0.48 9.5 0.1 2.1 3 0 0 3 3 3 0 RmuC family KxDL PF10241.9 KKF93039.1 - 0.75 10.1 3.0 14 6.1 0.3 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF2205 PF10224.9 KKF93039.1 - 1.2 9.2 3.6 2.2 8.3 0.6 2.4 2 1 0 2 2 2 0 Short coiled-coil protein TPR_MLP1_2 PF07926.12 KKF93039.1 - 7.7 6.6 8.5 10 6.2 0.1 2.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein CHCH PF06747.13 KKF93040.1 - 6.9e-05 22.9 4.9 0.00011 22.2 4.9 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KKF93040.1 - 0.00068 20.0 0.8 0.0023 18.3 0.8 1.9 1 0 0 1 1 1 1 GCK domain DUF5353 PF17304.2 KKF93041.1 - 0.82 9.5 4.1 1.6 8.6 4.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Myb_DNA-bind_3 PF12776.7 KKF93042.1 - 6.6e-20 71.9 4.9 8.4e-20 71.6 4.9 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KKF93042.1 - 0.031 14.6 1.8 0.054 13.9 1.8 1.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 KKF93042.1 - 0.059 14.0 0.2 0.097 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF573 zf-C2HC5 PF06221.13 KKF93043.1 - 3.8e-20 71.6 6.9 6.4e-20 70.9 6.9 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.6 KKF93043.1 - 0.15 11.5 4.0 4.2 6.9 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKF93043.1 - 1.2 8.9 5.5 20 5.1 5.8 2.3 1 1 1 2 2 2 0 zinc-ribbon domain Ldh_1_N PF00056.23 KKF93044.1 - 1.7e-43 148.1 0.0 2.9e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KKF93044.1 - 2.2e-43 148.1 0.0 3.8e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KKF93044.1 - 1.4e-06 27.6 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KKF93044.1 - 0.0031 17.9 0.1 0.01 16.2 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain E1-E2_ATPase PF00122.20 KKF93045.1 - 3e-18 66.0 0.0 7.3e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KKF93045.1 - 8.3e-13 49.1 3.4 6.2e-07 29.9 2.6 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKF93045.1 - 0.0085 15.9 0.4 0.1 12.3 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKF93045.1 - 0.019 15.0 0.0 0.058 13.5 0.0 1.8 2 0 0 2 2 2 0 Cation transport ATPase (P-type) DUF4059 PF13268.6 KKF93045.1 - 0.19 12.1 3.4 16 6.0 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) G0-G1_switch_2 PF15103.6 KKF93045.1 - 5 7.6 5.3 23 5.5 0.7 2.8 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF1682 PF07946.14 KKF93046.1 - 1.1e-103 346.8 0.1 1.3e-103 346.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Pinin_SDK_memA PF04696.13 KKF93047.1 - 1.3e-29 102.9 15.8 3.3e-29 101.6 15.8 1.7 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region Abhydrolase_1 PF00561.20 KKF93048.1 - 2.3e-22 79.9 0.1 2.8e-16 59.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKF93048.1 - 9.3e-16 59.1 2.4 1.2e-15 58.7 2.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKF93048.1 - 1e-12 47.9 0.0 1.3e-10 40.9 0.0 2.3 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KKF93048.1 - 0.011 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.13 KKF93048.1 - 0.085 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PhoLip_ATPase_C PF16212.5 KKF93049.1 - 5.3e-80 268.8 15.7 5.3e-80 268.8 15.7 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKF93049.1 - 6.6e-27 93.0 7.9 6.6e-27 93.0 7.9 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KKF93049.1 - 1.7e-12 47.3 0.0 8.2e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKF93049.1 - 2.5e-12 47.5 3.9 1.8e-07 31.6 1.9 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KKF93049.1 - 1.9e-06 27.5 0.2 4.5e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KKF93049.1 - 0.00067 19.5 0.3 0.011 15.5 0.1 2.3 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ecl1 PF12855.7 KKF93050.1 - 1.3e-16 62.3 11.9 3e-11 44.8 8.3 2.2 1 1 1 2 2 2 2 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KKF93050.1 - 0.0041 17.2 1.7 0.0077 16.3 1.7 1.4 1 0 0 1 1 1 1 MYND finger SnAC PF14619.6 KKF93050.1 - 0.011 16.3 0.9 0.021 15.4 0.9 1.5 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex PH_4 PF15404.6 KKF93050.1 - 0.1 12.4 0.3 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Clr5 PF14420.6 KKF93051.1 - 1.2e-23 83.1 1.1 3e-23 81.8 0.8 1.9 2 0 0 2 2 2 1 Clr5 domain GST_N_3 PF13417.6 KKF93052.1 - 2e-13 50.5 0.0 4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KKF93052.1 - 5.5e-13 49.1 0.0 1.4e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKF93052.1 - 3e-11 43.4 0.0 6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKF93052.1 - 5e-11 42.7 0.0 9.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKF93052.1 - 2.4e-10 40.6 0.0 6.1e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKF93052.1 - 3.9e-07 30.0 0.0 7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SF1-HH PF16275.5 KKF93053.1 - 1.7e-43 147.5 5.3 2.7e-43 146.9 0.5 2.4 1 1 1 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KKF93053.1 - 1.9e-08 34.0 0.1 3.5e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 KH domain Peptidase_M28 PF04389.17 KKF93054.1 - 2e-22 79.8 0.1 2.1e-14 53.7 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M28 Peptidase_M20 PF01546.28 KKF93054.1 - 0.043 13.5 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Med11 PF10280.9 KKF93055.1 - 7.6e-37 126.8 0.7 2.7e-34 118.6 0.3 2.0 2 0 0 2 2 2 2 Mediator complex protein Mst1_SARAH PF11629.8 KKF93055.1 - 0.065 13.3 0.0 8.6 6.5 0.0 2.4 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 TFIID_NTD2 PF04494.15 KKF93056.1 - 2.5e-38 131.3 0.6 3.5e-38 130.8 0.6 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 KKF93056.1 - 8.2e-37 124.6 17.4 1.9e-08 34.8 0.9 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF93056.1 - 2.4e-11 43.8 0.1 0.088 13.1 0.0 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KKF93056.1 - 2.9e-06 27.0 0.0 6.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KKF93056.1 - 4.8e-05 23.3 0.1 0.0014 18.6 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KKF93056.1 - 0.083 11.8 0.3 16 4.3 0.0 2.8 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AsnC_trans_reg PF01037.21 KKF93056.1 - 0.21 11.6 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain Vps5 PF09325.10 KKF93057.1 - 6e-87 291.1 6.1 6e-87 291.1 6.1 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KKF93057.1 - 1.1e-24 86.6 0.1 2.8e-24 85.3 0.1 1.7 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 KKF93057.1 - 0.012 15.1 0.8 0.25 10.8 0.2 2.2 1 1 1 2 2 2 0 WASP-binding domain of Sorting nexin protein BAR_3 PF16746.5 KKF93057.1 - 0.013 15.3 8.6 0.014 15.1 4.1 2.3 1 1 1 2 2 2 0 BAR domain of APPL family BAR_2 PF10455.9 KKF93057.1 - 0.065 12.4 2.1 0.11 11.6 2.1 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KKF93057.1 - 2.6 7.6 9.5 28 4.2 9.5 2.2 1 1 0 1 1 1 0 BAR domain Ribosomal_L31 PF01197.18 KKF93058.1 - 1.1e-05 25.6 0.1 2.2e-05 24.6 0.0 1.6 1 1 1 2 2 2 1 Ribosomal protein L31 YceD PF02620.17 KKF93058.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD Kinesin PF00225.23 KKF93059.1 - 2.9e-105 351.9 0.8 7.2e-105 350.6 0.8 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKF93059.1 - 5.3e-56 188.7 0.1 2.3e-55 186.6 0.1 2.2 1 0 0 1 1 1 1 Microtubule binding ADIP PF11559.8 KKF93059.1 - 0.00027 21.0 42.1 0.04 14.0 21.5 3.7 1 1 2 3 3 3 3 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 KKF93059.1 - 0.0016 18.4 5.3 0.0016 18.4 5.3 4.5 1 1 3 4 4 3 1 BRE1 E3 ubiquitin ligase Tropomyosin_1 PF12718.7 KKF93059.1 - 0.0028 17.8 16.0 0.0028 17.8 16.0 4.3 2 1 1 3 3 3 1 Tropomyosin like AAA_16 PF13191.6 KKF93059.1 - 0.0091 16.4 3.6 0.012 16.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain WEMBL PF05701.11 KKF93059.1 - 0.07 11.8 41.6 0.0088 14.8 22.6 2.7 2 1 1 3 3 3 0 Weak chloroplast movement under blue light bZIP_1 PF00170.21 KKF93059.1 - 0.16 12.1 0.2 0.16 12.1 0.2 5.8 2 2 3 5 5 5 0 bZIP transcription factor AAA_22 PF13401.6 KKF93059.1 - 0.36 11.1 2.7 0.66 10.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain Lebercilin PF15619.6 KKF93059.1 - 0.86 9.2 43.9 1.7 8.3 32.3 3.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease KMP11 PF03037.16 KKF93059.1 - 1 10.2 14.9 0.036 14.9 7.6 2.5 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 Filament PF00038.21 KKF93059.1 - 1.3 8.6 47.0 0.15 11.6 40.8 2.8 2 1 0 2 2 2 0 Intermediate filament protein FliD_C PF07195.12 KKF93059.1 - 1.9 7.9 23.8 0.55 9.6 10.2 3.2 2 1 2 4 4 4 0 Flagellar hook-associated protein 2 C-terminus FPP PF05911.11 KKF93059.1 - 1.9 6.6 45.1 0.77 7.9 30.2 2.5 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil Phage_tail_T PF06223.12 KKF93059.1 - 2.8 8.5 4.8 7.2 7.2 0.4 2.9 3 0 0 3 3 3 0 Minor tail protein T Fez1 PF06818.15 KKF93059.1 - 4 7.8 48.2 3.3 8.1 27.8 3.5 2 1 1 3 3 3 0 Fez1 Baculo_PEP_C PF04513.12 KKF93059.1 - 4.6 7.3 14.2 2.6 8.1 6.1 3.2 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.8 KKF93059.1 - 6.5 6.8 46.1 0.041 13.9 4.6 6.1 1 1 5 6 6 6 0 TATA element modulatory factor 1 DNA binding ILVD_EDD PF00920.21 KKF93060.1 - 2.2e-209 696.4 0.1 2.6e-209 696.2 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family HSP90 PF00183.18 KKF93061.1 - 1.1e-223 743.8 31.5 1.4e-223 743.5 31.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KKF93061.1 - 1.7e-13 51.1 0.1 3.2e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KKF93061.1 - 4.3e-09 36.3 0.1 1.2e-08 34.8 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KKF93061.1 - 0.065 13.3 0.2 0.22 11.5 0.2 1.9 1 0 0 1 1 1 0 Tumour suppressor protein GCD14 PF08704.10 KKF93062.1 - 0.00013 21.7 0.0 0.004 16.8 0.0 2.5 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.12 KKF93063.1 - 0.012 16.3 0.0 0.026 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KKF93063.1 - 0.071 13.8 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FAM220 PF15487.6 KKF93063.1 - 0.27 10.8 4.3 0.16 11.5 0.2 2.6 3 0 0 3 3 3 0 FAM220 family Ytp1 PF10355.9 KKF93064.1 - 3.5e-57 193.7 22.6 3.5e-57 193.7 22.6 2.5 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KKF93064.1 - 7.4e-27 93.2 1.6 7.4e-27 93.2 1.6 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) ADH_zinc_N PF00107.26 KKF93066.1 - 7.7e-22 77.7 0.1 1.2e-21 77.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KKF93066.1 - 1.7e-17 63.3 0.0 3.9e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KKF93066.1 - 4.9e-08 34.1 0.0 8.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPR_2 PF07719.17 KKF93067.1 - 6.9e-08 32.0 2.4 0.0012 18.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKF93067.1 - 2.2e-05 24.0 0.6 4.2 7.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKF93067.1 - 2.6e-05 24.4 2.9 0.046 14.0 0.7 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKF93067.1 - 0.00011 22.7 0.5 0.028 14.9 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKF93067.1 - 0.00011 22.1 0.3 0.067 13.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Pkinase PF00069.25 KKF93069.1 - 1.3e-51 175.6 0.0 1.8e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF93069.1 - 1.3e-29 103.3 0.0 1.6e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF93069.1 - 0.00076 18.9 0.0 0.0019 17.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KKF93069.1 - 0.0067 16.4 0.3 0.18 11.7 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKF93069.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KKF93069.1 - 0.048 13.2 0.0 0.081 12.5 0.0 1.4 1 1 0 1 1 1 0 RIO1 family RNA_pol_L_2 PF13656.6 KKF93071.1 - 2.6e-30 104.0 0.0 3.7e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KKF93071.1 - 1.8e-10 40.1 0.0 2.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR PF05347.15 KKF93072.1 - 7.2e-06 26.0 0.5 1.6e-05 24.8 0.1 1.8 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KKF93072.1 - 5.6e-05 23.8 0.0 7.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF684 PF05075.14 KKF93072.1 - 0.009 15.0 0.8 0.012 14.6 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF684) EST1_DNA_bind PF10373.9 KKF93073.1 - 1.8e-23 83.4 0.4 3.4e-23 82.5 0.0 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KKF93073.1 - 9.5e-14 52.2 0.5 2.6e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 GRDP-like PF07173.12 KKF93073.1 - 0.022 15.4 0.2 0.052 14.2 0.2 1.6 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like F-box-like_2 PF13013.6 KKF93073.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain PfkB PF00294.24 KKF93074.1 - 5.7e-67 226.1 0.1 6.5e-67 226.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KKF93074.1 - 0.0088 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Ribosomal_L2_C PF03947.18 KKF93075.1 - 6.5e-43 145.9 5.3 6.5e-43 145.9 5.3 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KKF93075.1 - 1.6e-14 53.6 0.3 4.8e-14 52.1 0.2 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain DUF1770 PF08589.10 KKF93077.1 - 1.4e-18 67.7 0.1 1.7e-18 67.4 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) eRF1_2 PF03464.15 KKF93078.1 - 1.9e-48 164.1 0.1 3.6e-48 163.3 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KKF93078.1 - 5.6e-39 133.1 0.8 1.2e-38 132.1 0.8 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KKF93078.1 - 3.3e-22 78.9 0.0 6.2e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KKF93078.1 - 1e-10 42.0 0.1 1.6e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KKF93078.1 - 2.7e-10 40.6 0.0 5.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 PTSIIB_sorb PF03830.15 KKF93078.1 - 0.08 13.2 1.6 1.4 9.1 0.0 2.6 2 1 1 3 3 3 0 PTS system sorbose subfamily IIB component PQ-loop PF04193.14 KKF93079.1 - 4.7e-39 132.0 14.9 1.7e-19 69.3 4.5 3.0 3 0 0 3 3 3 2 PQ loop repeat HTH_Bact PF18768.1 KKF93079.1 - 0.0082 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix bacterial domain ER_lumen_recept PF00810.18 KKF93079.1 - 0.043 14.6 0.6 18 6.2 0.1 2.6 2 0 0 2 2 2 0 ER lumen protein retaining receptor MaoC_dehydratas PF01575.19 KKF93080.1 - 4.7e-05 22.9 0.0 6.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain Glyco_transf_28 PF03033.20 KKF93081.1 - 4.8e-13 49.3 3.7 5.2e-12 46.0 0.8 3.2 3 1 0 3 3 3 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KKF93081.1 - 1.4e-07 30.8 0.0 2.7e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Kinetochor_Ybp2 PF08568.10 KKF93082.1 - 6.8e-67 226.4 0.0 9.2e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin F-box-like PF12937.7 KKF93083.1 - 0.15 11.9 0.4 0.33 10.9 0.1 1.7 2 0 0 2 2 2 0 F-box-like Aminotran_3 PF00202.21 KKF93084.1 - 2.5e-116 388.7 0.0 2.9e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KKF93084.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KKF93084.1 - 0.025 13.8 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II OAM_dimer PF16554.5 KKF93084.1 - 0.13 12.7 0.1 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase DUF3543 PF12063.8 KKF93085.1 - 9.2e-75 251.3 0.1 1.3e-74 250.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KKF93085.1 - 7.9e-66 222.1 0.0 1.8e-65 221.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF93085.1 - 1.4e-36 126.1 0.0 3e-36 125.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKF93085.1 - 0.0087 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKF93085.1 - 0.013 15.4 0.2 0.066 13.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKF93085.1 - 0.07 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KKF93085.1 - 0.087 12.1 0.0 4.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Kinase-like CLZ PF16526.5 KKF93085.1 - 2.2 8.7 5.8 21 5.6 0.0 3.1 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels adh_short PF00106.25 KKF93086.1 - 6.4e-29 100.8 0.0 8.6e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF93086.1 - 4.2e-19 69.0 0.0 6.3e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF93086.1 - 3.1e-08 33.7 0.2 1.1e-07 32.0 0.2 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 KKF93086.1 - 0.0017 18.7 0.1 0.0076 16.7 0.0 2.0 2 1 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KKF93086.1 - 0.024 14.5 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KKF93086.1 - 0.036 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KKF93086.1 - 0.049 13.1 0.0 0.098 12.1 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KKF93086.1 - 0.21 11.7 0.4 0.45 10.6 0.4 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sas10 PF09368.10 KKF93087.1 - 1e-28 99.6 9.0 1e-28 99.6 9.0 2.7 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KKF93087.1 - 3e-10 40.6 0.0 1.4e-09 38.5 0.0 2.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family TPT PF03151.16 KKF93088.1 - 7.6e-57 192.9 9.6 1e-56 192.5 9.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KKF93088.1 - 5e-07 30.0 31.9 0.0048 17.1 11.2 3.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KKF93088.1 - 2.5e-05 23.6 12.7 0.00087 18.6 12.7 2.3 1 1 0 1 1 1 1 UAA transporter family SLATT_5 PF18160.1 KKF93088.1 - 0.038 13.3 0.0 0.087 12.1 0.0 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 PSII PF00421.19 KKF93088.1 - 0.051 12.3 0.0 0.084 11.5 0.0 1.3 1 0 0 1 1 1 0 Photosystem II protein ORC5_C PF14630.6 KKF93089.1 - 1.8e-43 149.1 0.1 6.9e-36 124.2 0.0 2.6 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 5 C-terminus ATP-synt_ab PF00006.25 KKF93090.1 - 1.2e-61 208.1 0.0 5e-61 206.1 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Alpha-amylase_C PF02806.18 KKF93090.1 - 5e-24 84.6 0.1 1.6e-23 83.0 0.1 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain ATP-synt_ab_N PF02874.23 KKF93090.1 - 4.1e-22 78.5 0.4 1.4e-21 76.7 0.3 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain CBM_48 PF02922.18 KKF93090.1 - 1.1e-18 67.3 0.0 3e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KKF93090.1 - 3.5e-14 53.1 0.3 8.1e-11 42.1 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AAA PF00004.29 KKF93090.1 - 0.0034 17.8 0.2 0.43 11.0 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) T3SS_ATPase_C PF18269.1 KKF93090.1 - 0.026 14.4 0.8 0.11 12.4 0.8 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RsgA_GTPase PF03193.16 KKF93090.1 - 0.037 13.9 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AMPK1_CBM PF16561.5 KKF93090.1 - 0.051 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase NB-ARC PF00931.22 KKF93090.1 - 0.083 12.1 0.4 0.24 10.5 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 KKF93090.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 KKF93090.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 KKF93090.1 - 0.28 11.5 0.9 1.4 9.2 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KKF93091.1 - 1e-32 113.6 0.0 2.3e-32 112.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KKF93091.1 - 1.5e-12 48.1 0.0 2.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKF93091.1 - 3.3e-07 30.4 0.0 7.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 KKF93091.1 - 9.2e-07 28.8 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 KKF93091.1 - 6.3e-06 25.4 0.0 1.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 KKF93091.1 - 0.0002 21.6 0.2 0.0019 18.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KKF93091.1 - 0.0029 17.6 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KKF93091.1 - 0.0032 17.0 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KKF93091.1 - 0.0044 17.4 0.6 0.012 16.0 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KKF93091.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKF93091.1 - 0.03 13.7 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KKF93091.1 - 0.03 14.9 0.0 0.068 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KKF93091.1 - 0.096 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 KKF93091.1 - 0.1 12.9 1.0 0.59 10.5 0.1 2.7 3 1 1 4 4 4 0 AAA domain T2SSE PF00437.20 KKF93091.1 - 0.1 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 KKF93091.1 - 0.14 11.9 0.0 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 KKF93091.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 KKF93091.1 - 0.16 11.6 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KKF93091.1 - 0.17 11.3 0.0 0.63 9.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 KKF93091.1 - 0.18 11.6 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KKF93091.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KKF93091.1 - 0.19 11.9 0.0 0.52 10.4 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_15 PF13175.6 KKF93091.1 - 0.24 11.1 0.2 0.36 10.5 0.2 1.2 1 0 0 1 1 1 0 AAA ATPase domain COX4 PF02936.14 KKF93092.1 - 4.5e-48 162.8 0.3 5.3e-48 162.5 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.11 KKF93092.1 - 0.038 14.3 1.2 0.05 14.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Paf1 PF03985.13 KKF93093.1 - 7.3e-82 275.6 0.7 8.2e-82 275.5 0.7 1.0 1 0 0 1 1 1 1 Paf1 Glyco_transf_90 PF05686.12 KKF93094.1 - 1.2e-17 63.9 5.6 1.7e-11 43.7 3.5 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_S8 PF00410.19 KKF93095.1 - 2.2e-22 79.3 0.1 3e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.26 KKF93096.1 - 5.6e-28 96.5 0.8 7.3e-28 96.2 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KKF93096.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain Rotamase_3 PF13616.6 KKF93097.1 - 5.9e-15 55.8 1.0 1e-14 55.0 0.2 1.8 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.21 KKF93097.1 - 1.4e-14 54.8 1.1 3.1e-14 53.7 0.1 1.8 1 1 0 2 2 2 1 PPIC-type PPIASE domain SAD_SRA PF02182.17 KKF93098.1 - 4.2e-05 23.3 0.0 5.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain MSA-2c PF12238.8 KKF93098.1 - 0.54 10.2 4.4 0.76 9.7 4.4 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c CAP_N PF01213.19 KKF93098.1 - 9 5.7 7.0 12 5.2 7.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TruD PF01142.18 KKF93099.1 - 3.3e-61 207.3 0.1 6.4e-57 193.2 0.0 3.2 1 1 1 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF3720 PF12517.8 KKF93099.1 - 3.4 8.7 11.3 1.1 10.3 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3720) Pkinase PF00069.25 KKF93100.1 - 3.2e-62 210.3 0.0 4e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF93100.1 - 9.6e-34 116.8 0.0 1.5e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF93100.1 - 2e-06 27.4 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKF93100.1 - 0.00042 19.2 0.0 0.00059 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KKF93100.1 - 0.038 13.9 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KKF93100.1 - 0.057 13.0 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DLH PF01738.18 KKF93101.1 - 5.4e-20 71.9 0.0 1.3e-18 67.3 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KKF93101.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Rep_fac-A_C PF08646.10 KKF93102.1 - 7e-54 181.5 0.3 8.9e-52 174.7 0.1 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KKF93102.1 - 1.2e-36 124.6 0.5 2.7e-36 123.4 0.5 1.6 1 0 0 1 1 1 1 Replication protein A OB domain Rep-A_N PF04057.12 KKF93102.1 - 1.2e-17 63.8 0.0 2.6e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KKF93102.1 - 1.3e-15 57.1 0.0 3.8e-10 39.6 0.0 3.7 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KKF93102.1 - 2.6e-06 27.3 0.4 0.94 9.1 0.0 3.2 3 0 0 3 3 3 3 Cell division control protein 24, OB domain 3 DUF4539 PF15072.6 KKF93102.1 - 0.00094 19.2 0.0 0.0062 16.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) DUF223 PF02721.14 KKF93102.1 - 0.0012 19.1 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF223 POT1 PF02765.17 KKF93102.1 - 0.0027 17.5 0.1 0.0089 15.9 0.1 1.8 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 zf-like PF04071.12 KKF93102.1 - 0.037 13.9 0.9 0.083 12.8 0.9 1.5 1 0 0 1 1 1 0 Cysteine-rich small domain DUF3837 PF12939.7 KKF93103.1 - 0.013 15.9 0.7 0.6 10.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) FlgN PF05130.12 KKF93103.1 - 0.024 15.2 0.1 0.03 14.8 0.1 1.1 1 0 0 1 1 1 0 FlgN protein zf-PHD-like PF15446.6 KKF93104.1 - 3e-52 176.6 5.7 3e-52 176.6 5.7 1.9 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KKF93104.1 - 4.5e-34 117.7 6.7 9.7e-26 90.3 0.1 3.0 1 1 2 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.31 KKF93104.1 - 2.8e-15 56.6 0.0 7.6e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KKF93104.1 - 0.0026 17.0 0.0 0.0026 17.0 0.0 2.7 2 1 1 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KKF93104.1 - 0.0028 17.5 1.3 0.012 15.5 0.5 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KKF93104.1 - 0.67 9.9 9.6 0.45 10.5 0.5 2.6 2 0 0 2 2 2 0 PHD-finger TIP49 PF06068.13 KKF93105.1 - 3.8e-168 559.2 0.1 5e-168 558.8 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KKF93105.1 - 5.8e-25 87.2 0.1 2e-24 85.5 0.1 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KKF93105.1 - 2.3e-10 41.0 0.2 1.2e-06 29.0 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKF93105.1 - 7.8e-10 38.7 0.1 2.5e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KKF93105.1 - 0.0002 21.7 0.3 0.23 11.7 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKF93105.1 - 0.00059 20.3 0.1 0.0055 17.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KKF93105.1 - 0.0012 19.1 0.2 0.0032 17.7 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKF93105.1 - 0.0016 18.8 2.3 0.15 12.4 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KKF93105.1 - 0.0027 17.7 0.1 0.14 12.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KKF93105.1 - 0.0041 16.7 0.1 0.026 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KKF93105.1 - 0.014 14.8 0.2 0.28 10.5 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 KKF93105.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 KKF93105.1 - 0.022 14.1 0.3 0.062 12.6 0.2 1.7 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 KKF93105.1 - 0.023 14.4 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KKF93105.1 - 0.025 14.3 0.1 0.051 13.3 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KKF93105.1 - 0.027 15.0 0.1 0.07 13.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KKF93105.1 - 0.065 12.5 0.1 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KKF93105.1 - 0.078 12.7 0.3 3.5 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKF93105.1 - 0.12 11.9 0.1 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 KKF93105.1 - 0.15 12.0 0.1 8.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TFIID-18kDa PF02269.16 KKF93106.1 - 1.6e-17 63.3 0.0 2.4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KKF93106.1 - 2.3e-05 24.3 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 KKF93106.1 - 0.0011 19.4 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KKF93106.1 - 0.0039 17.3 0.1 0.0086 16.2 0.0 1.6 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KKF93106.1 - 0.0089 16.4 0.9 0.029 14.8 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KKF93106.1 - 0.033 14.7 0.0 0.11 13.1 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A MtrB PF05440.12 KKF93106.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B Tcp11 PF05794.13 KKF93107.1 - 4.9e-96 322.5 0.9 8.5e-96 321.7 0.9 1.4 1 0 0 1 1 1 1 T-complex protein 11 DUF3738 PF12543.8 KKF93107.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3738) DinB_2 PF12867.7 KKF93107.1 - 0.037 14.5 0.1 0.091 13.3 0.1 1.7 1 0 0 1 1 1 0 DinB superfamily Glyco_hydro_18 PF00704.28 KKF93108.1 - 7.9e-63 213.0 0.0 9.2e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KKF93109.1 - 1.5e-68 231.9 0.1 1.7e-68 231.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4226 PF10774.9 KKF93109.1 - 0.17 12.2 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Glyco_hydro_18 PF00704.28 KKF93110.1 - 6.3e-48 164.1 0.0 7.2e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KKF93111.1 - 3.5e-68 230.6 0.0 4.3e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKF93111.1 - 2e-06 28.1 21.5 3.1e-06 27.5 21.5 1.3 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_18 PF00704.28 KKF93112.1 - 1.5e-55 189.2 0.0 1.8e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UBA_4 PF14555.6 KKF93113.1 - 0.012 15.4 1.4 0.04 13.7 1.5 1.9 2 0 0 2 2 2 0 UBA-like domain UIM PF02809.20 KKF93113.1 - 0.1 12.6 3.7 0.33 11.0 3.7 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Sec1 PF00995.23 KKF93114.1 - 2.4e-125 420.0 0.0 2.8e-125 419.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family P16-Arc PF04699.14 KKF93114.1 - 0.17 12.4 0.9 0.43 11.1 0.9 1.7 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DnaJ_C PF01556.18 KKF93115.1 - 2.3e-39 134.9 0.3 3.1e-39 134.4 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKF93115.1 - 3.2e-26 91.2 4.3 5.6e-26 90.5 4.3 1.4 1 0 0 1 1 1 1 DnaJ domain HAD_2 PF13419.6 KKF93116.1 - 5.6e-18 65.7 0.0 7.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKF93116.1 - 1.4e-08 35.2 0.1 3.7e-08 33.9 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKF93116.1 - 1.1e-07 31.7 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 KKF93116.1 - 0.00053 19.8 0.0 0.15 11.8 0.0 2.2 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase HAD PF12710.7 KKF93116.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_tran_WecB PF03808.13 KKF93116.1 - 0.18 11.8 0.0 7.6 6.5 0.0 2.4 2 1 1 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family MFS_1 PF07690.16 KKF93117.1 - 5.9e-42 143.8 49.3 5.9e-42 143.8 49.3 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKF93117.1 - 3.5e-16 59.1 12.4 3.5e-16 59.1 12.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MARVEL PF01284.23 KKF93118.1 - 4.9e-05 23.4 10.3 8.3e-05 22.6 10.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF1345 PF07077.11 KKF93118.1 - 0.0035 17.1 0.2 0.11 12.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1345) DUF4281 PF14108.6 KKF93118.1 - 0.045 14.1 0.9 0.084 13.2 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Nop16 PF09420.10 KKF93119.1 - 4.5e-64 216.3 0.7 5.2e-64 216.1 0.7 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Sec16_C PF12931.7 KKF93120.1 - 2.4e-106 355.8 0.0 3.2e-106 355.4 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KKF93120.1 - 2.4e-22 79.7 0.0 7.2e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Hus1 PF04005.12 KKF93121.1 - 3.8e-72 242.9 0.0 5.3e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Hus1-like protein GSHPx PF00255.19 KKF93122.1 - 2.8e-39 133.0 0.1 3.7e-39 132.7 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 KKF93122.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Redoxin 2-Hacid_dh_C PF02826.19 KKF93123.1 - 2e-38 131.6 0.0 4.2e-38 130.5 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKF93123.1 - 2e-22 79.3 9.0 3.4e-22 78.6 9.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KKF93123.1 - 0.0016 19.0 0.9 0.016 15.8 0.5 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 KKF93123.1 - 0.0046 17.0 0.3 0.013 15.6 0.3 1.8 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 KKF93123.1 - 0.02 15.3 0.8 0.12 12.9 0.2 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 KKF93123.1 - 0.04 13.5 0.6 0.1 12.2 0.2 2.0 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KKF93123.1 - 0.044 14.0 0.5 0.12 12.5 0.2 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KKF93123.1 - 0.047 13.3 0.5 0.11 12.1 0.5 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 KKF93124.1 - 9.5e-59 199.7 4.4 1.3e-58 199.3 4.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKF93124.1 - 4.1e-07 29.4 4.0 5.7e-07 29.0 4.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKF93124.1 - 1e-06 28.2 0.4 0.0019 17.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKF93124.1 - 9.8e-06 26.0 0.5 0.0056 17.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKF93124.1 - 2.2e-05 24.6 0.2 5.9e-05 23.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 KKF93124.1 - 0.00016 21.2 0.6 0.0032 16.9 0.2 2.1 2 0 0 2 2 2 1 GMC oxidoreductase MCRA PF06100.11 KKF93124.1 - 0.00037 19.4 0.9 0.0024 16.7 0.2 2.1 2 0 0 2 2 2 1 MCRA family Trp_halogenase PF04820.14 KKF93124.1 - 0.001 18.1 0.8 0.0058 15.5 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 KKF93124.1 - 0.0064 16.7 1.2 0.45 10.8 0.1 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain FAD_oxidored PF12831.7 KKF93124.1 - 0.031 13.6 1.9 0.12 11.7 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KKF93124.1 - 0.032 13.5 0.2 0.081 12.1 0.2 1.6 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.15 KKF93124.1 - 0.063 11.8 0.2 2 6.9 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) ApbA PF02558.16 KKF93124.1 - 0.14 11.8 0.3 0.3 10.7 0.3 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Mersacidin PF16934.5 KKF93124.1 - 0.19 11.5 1.0 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) NAD_binding_9 PF13454.6 KKF93124.1 - 0.32 11.0 3.6 0.34 10.9 0.2 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding CLPTM1 PF05602.12 KKF93125.1 - 2.1e-137 458.7 0.0 2.6e-137 458.4 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1772 PF08592.11 KKF93125.1 - 0.16 12.3 1.4 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF1453 PF07301.11 KKF93125.1 - 0.36 10.8 4.7 0.53 10.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) Gti1_Pac2 PF09729.9 KKF93126.1 - 0.29 11.2 4.1 2.6 8.1 4.1 2.4 1 1 0 1 1 1 0 Gti1/Pac2 family SPX PF03105.19 KKF93126.1 - 1.8 8.4 11.7 0.23 11.4 3.5 2.1 2 0 0 2 2 2 0 SPX domain Longin PF13774.6 KKF93127.1 - 6.7e-25 86.9 0.2 1.1e-24 86.3 0.2 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KKF93127.1 - 5.4e-16 58.2 0.1 1e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.12 KKF93127.1 - 0.025 14.6 0.9 0.27 11.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sirohm_synth_C PF14823.6 KKF93127.1 - 0.15 11.7 0.4 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal DUF4404 PF14357.6 KKF93127.1 - 0.39 11.4 1.8 24 5.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ASXH PF13919.6 KKF93128.1 - 3.6e-24 85.3 0.0 4.5e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Asx homology domain Glyoxalase_2 PF12681.7 KKF93128.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Fungal_trans PF04082.18 KKF93129.1 - 9.4e-11 41.2 0.1 3.4e-10 39.4 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF93129.1 - 1.4e-08 34.7 9.9 2.4e-08 33.9 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ndc1_Nup PF09531.10 KKF93129.1 - 3.4 6.2 8.8 5.6 5.5 8.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Elong_Iki1 PF10483.9 KKF93130.1 - 4.4e-81 272.6 0.0 8.4e-81 271.7 0.0 1.4 1 1 0 1 1 1 1 Elongator subunit Iki1 Gly-zipper_Omp PF13488.6 KKF93130.1 - 2.4 8.2 5.9 5.8 7.0 5.9 1.6 1 0 0 1 1 1 0 Glycine zipper Peptidase_M13_N PF05649.13 KKF93131.1 - 2.4e-36 126.2 0.0 2.8e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KKF93132.1 - 2.4e-64 218.4 0.0 3.1e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KKF93132.1 - 9.6e-48 162.5 0.0 1.7e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 TFIID_20kDa PF03847.13 KKF93134.1 - 0.12 12.9 1.0 0.49 10.9 0.7 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A DAO PF01266.24 KKF93136.1 - 3.3e-50 171.6 0.0 5.2e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KKF93136.1 - 5.2e-45 152.4 0.0 9.6e-45 151.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KKF93136.1 - 9.5e-07 28.2 0.3 2.4e-06 26.9 0.3 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KKF93136.1 - 8.4e-06 25.4 0.4 0.0022 17.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKF93136.1 - 0.00098 18.5 0.0 0.67 9.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KKF93136.1 - 0.0017 17.7 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKF93136.1 - 0.011 15.1 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 KKF93136.1 - 0.042 12.4 0.7 1.2 7.5 0.1 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KKF93136.1 - 0.062 13.5 0.2 0.23 11.7 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKF93136.1 - 0.072 13.7 0.6 0.39 11.3 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKF93136.1 - 0.098 11.7 1.2 0.49 9.4 0.3 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KKF93136.1 - 0.098 11.9 3.3 0.52 9.5 0.5 2.2 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 KKF93136.1 - 0.11 12.4 0.3 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KKF93136.1 - 0.15 10.7 0.3 0.24 10.1 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein PTH2 PF01981.16 KKF93137.1 - 6.1e-34 116.8 0.3 1.3e-33 115.8 0.3 1.5 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SelK_SelG PF10961.8 KKF93138.1 - 0.047 14.3 0.6 0.78 10.4 0.0 2.8 2 0 0 2 2 2 0 Selenoprotein SelK_SelG CCDC71L PF15374.6 KKF93138.1 - 0.66 9.2 6.8 0.073 12.3 1.2 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L HBB PF06777.11 KKF93139.1 - 1.2e-46 158.9 1.8 2.4e-42 144.8 0.5 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KKF93139.1 - 5.3e-44 150.4 0.1 1.7e-43 148.8 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KKF93139.1 - 3.2e-34 118.1 1.6 4.2e-34 117.7 0.4 1.8 2 0 0 2 2 2 1 DEAD_2 Meis_PKNOX_N PF16493.5 KKF93139.1 - 0.11 12.8 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 SNF2_N PF00176.23 KKF93139.1 - 0.19 10.4 0.0 0.36 9.5 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Latarcin PF10279.9 KKF93139.1 - 3.5 8.1 5.6 6.6 7.2 4.4 2.1 2 0 0 2 2 2 0 Latarcin precursor zf-C2H2 PF00096.26 KKF93140.1 - 2e-15 56.3 18.1 4.9e-05 23.6 0.5 4.0 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKF93140.1 - 1.2e-10 41.3 16.7 0.00058 20.5 0.5 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKF93140.1 - 0.0031 17.9 2.2 0.0031 17.9 2.2 4.4 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2HC_2 PF13913.6 KKF93140.1 - 0.0067 16.3 0.9 0.024 14.5 0.9 2.0 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KKF93140.1 - 0.039 13.7 0.5 0.039 13.7 0.5 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-CHCC PF10276.9 KKF93140.1 - 0.084 12.9 0.5 0.29 11.2 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_8 PF15909.5 KKF93140.1 - 0.13 12.6 6.8 0.58 10.5 6.7 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 KKF93140.1 - 0.26 12.0 6.9 0.54 10.9 0.3 2.7 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KKF93140.1 - 0.44 10.9 9.6 0.39 11.1 3.4 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KKF93140.1 - 0.5 10.4 10.3 0.2 11.7 6.1 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_aberr PF17017.5 KKF93140.1 - 0.68 10.0 6.9 0.21 11.7 0.5 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger zf-TRAF PF02176.18 KKF93140.1 - 1.1 9.9 12.4 0.64 10.7 5.8 3.2 2 1 2 4 4 4 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 KKF93140.1 - 2.2 8.7 8.8 3.2 8.2 0.1 3.2 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RNA_pol_Rpb1_5 PF04998.17 KKF93141.1 - 2.7e-88 295.9 0.0 1.2e-87 293.8 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KKF93141.1 - 1.4e-67 227.1 0.1 3e-67 226.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KKF93141.1 - 1.1e-31 110.4 0.3 1.1e-30 107.0 0.1 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KKF93141.1 - 1.5e-27 96.4 0.0 5.7e-27 94.6 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KKF93141.1 - 1.2e-16 60.6 0.0 6.9e-16 58.1 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PARP_reg PF02877.14 KKF93141.1 - 0.0044 17.1 1.3 0.02 15.0 0.4 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain Nop14 PF04147.12 KKF93141.1 - 0.71 8.0 18.2 1.3 7.1 18.2 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KKF93141.1 - 6.2 6.1 30.0 0.19 11.1 22.9 1.9 2 0 0 2 2 2 0 BUD22 Histone PF00125.24 KKF93142.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KKF93142.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KKF93142.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KKF93142.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KKF93142.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KKF93142.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KKF93142.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KKF93143.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KKF93143.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KKF93143.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KKF93143.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KKF93143.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KKF93143.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KKF93143.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KKF93143.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KKF93143.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region EPSP_synthase PF00275.20 KKF93144.1 - 1.4e-131 439.1 0.0 1.9e-131 438.6 0.0 1.1 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KKF93144.1 - 3e-101 338.0 0.0 4.5e-101 337.4 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KKF93144.1 - 8.4e-48 163.6 0.0 6.2e-46 157.5 0.0 3.0 2 1 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 KKF93144.1 - 2e-34 119.0 0.0 3.8e-32 111.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KKF93144.1 - 1.7e-24 85.8 0.0 2e-23 82.4 0.0 2.7 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KKF93144.1 - 7.6e-10 38.9 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KKF93144.1 - 1.5e-05 24.7 0.0 3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Putative_PNPOx PF01243.20 KKF93144.1 - 0.028 14.6 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase MFS_1 PF07690.16 KKF93145.1 - 2.6e-27 95.7 34.8 2.6e-27 95.7 34.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1828 PF08861.10 KKF93146.1 - 0.12 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF1828 DUF908 PF06012.12 KKF93146.1 - 9 5.6 5.8 12 5.2 5.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Mito_carr PF00153.27 KKF93147.1 - 1.3e-45 153.2 1.5 1.2e-19 70.0 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2717 PF10911.8 KKF93147.1 - 0.19 11.5 0.2 20 5.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2717) Cofilin_ADF PF00241.20 KKF93148.1 - 7.2e-33 113.0 0.0 1e-19 70.5 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein RIO1 PF01163.22 KKF93149.1 - 6.1e-69 231.4 0.1 6.1e-69 231.4 0.1 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KKF93149.1 - 0.0061 16.5 0.0 0.53 10.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KKF93149.1 - 0.016 14.6 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKF93149.1 - 0.08 12.5 0.6 0.36 10.4 0.6 2.1 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF2052 PF09747.9 KKF93149.1 - 4.6 7.3 16.5 0.52 10.4 9.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PTPRCAP PF15713.5 KKF93149.1 - 6.4 7.0 17.4 3.6 7.9 9.7 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated YL1 PF05764.13 KKF93149.1 - 7.6 6.6 25.0 1.6 8.8 16.2 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Lactonase PF10282.9 KKF93151.1 - 5.8e-51 173.8 0.0 7.9e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 KKF93151.1 - 0.0028 16.2 0.0 0.011 14.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome D1 heme domain RGI_lyase PF18370.1 KKF93151.1 - 0.056 13.8 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Rhamnogalacturonan I lyases beta-sheet domain Med22 PF06179.12 KKF93152.1 - 1.9e-13 50.5 0.0 2.6e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PseudoU_synth_1 PF01416.20 KKF93153.1 - 3.5e-12 46.7 0.0 9.1e-11 42.2 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase Sod_Fe_C PF02777.18 KKF93154.1 - 1e-36 125.2 0.4 1.7e-36 124.5 0.4 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KKF93154.1 - 2.7e-32 111.1 3.3 9.6e-32 109.3 1.5 2.2 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain UPF0086 PF01868.16 KKF93154.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function UPF0086 CBM_21 PF03370.13 KKF93155.1 - 8e-32 109.8 0.5 1.6e-31 108.8 0.5 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KKF93155.1 - 1.5e-08 35.1 0.3 3.1e-08 34.1 0.3 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) AAA PF00004.29 KKF93156.1 - 1.6e-17 64.2 0.0 2.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF4449 PF14613.6 KKF93157.1 - 1.9e-05 24.8 1.1 1.9e-05 24.8 1.1 5.4 4 1 0 4 4 4 1 Protein of unknown function (DUF4449) WD40 PF00400.32 KKF93158.1 - 2.2e-28 97.9 23.2 1.8e-07 31.7 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF93158.1 - 4.7e-08 33.2 0.4 0.011 16.0 0.0 5.3 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KKF93158.1 - 3.4e-06 26.9 0.1 7.1e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KKF93158.1 - 6.1e-06 25.2 0.2 0.0066 15.2 0.0 3.1 2 1 0 2 2 2 2 Nucleoporin Nup120/160 F-box PF00646.33 KKF93158.1 - 1.9e-05 24.4 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ PF01011.21 KKF93158.1 - 0.00036 20.3 0.0 0.85 9.7 0.0 3.0 2 0 0 2 2 2 2 PQQ enzyme repeat WD40_like PF17005.5 KKF93158.1 - 0.00043 19.7 0.5 0.053 12.8 0.0 3.0 3 0 0 3 3 3 1 WD40-like domain PQQ_2 PF13360.6 KKF93158.1 - 0.001 18.7 0.0 0.13 11.8 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 KKF93158.1 - 0.027 15.0 0.2 1e+02 3.5 0.0 4.5 4 0 0 4 4 4 0 PQQ-like domain Ge1_WD40 PF16529.5 KKF93158.1 - 0.029 13.3 0.1 0.19 10.6 0.1 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein APG17 PF04108.12 KKF93159.1 - 3.2e-61 207.6 17.7 7e-56 190.0 8.9 2.1 1 1 1 2 2 2 2 Autophagy protein Apg17 CLZ PF16526.5 KKF93159.1 - 0.076 13.4 3.7 21 5.5 0.3 3.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1926 PF09095.11 KKF93159.1 - 0.077 12.6 2.2 0.15 11.6 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1926) Flagellin_IN PF07196.13 KKF93159.1 - 0.1 12.8 4.9 1.4 9.2 2.1 2.4 2 0 0 2 2 2 0 Flagellin hook IN motif KxDL PF10241.9 KKF93159.1 - 0.16 12.3 3.8 1.5 9.2 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein CCDC-167 PF15188.6 KKF93159.1 - 4.7 7.6 9.1 11 6.5 0.8 3.7 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 YgaB PF14182.6 KKF93159.1 - 5.1 7.6 8.9 3.7 8.0 2.1 3.5 3 1 0 3 3 3 0 YgaB-like protein Sel1 PF08238.12 KKF93160.1 - 8.2e-41 137.5 22.9 6.7e-06 26.6 0.1 7.3 7 0 0 7 7 7 7 Sel1 repeat Pkinase PF00069.25 KKF93161.1 - 4.7e-64 216.3 0.0 6.5e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF93161.1 - 1.8e-36 125.8 0.0 2.7e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KKF93161.1 - 1.2e-06 28.6 0.1 0.0014 18.8 0.0 3.1 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 KKF93161.1 - 7.4e-06 25.5 0.0 2.6e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KKF93161.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KKF93161.1 - 0.024 13.4 0.2 0.042 12.6 0.2 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KKF93161.1 - 0.041 12.8 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Jacalin PF01419.17 KKF93162.1 - 1.6e-07 31.3 0.5 3.4e-07 30.2 0.3 1.7 2 0 0 2 2 2 1 Jacalin-like lectin domain MutS_V PF00488.21 KKF93163.1 - 5.3e-67 225.5 1.4 1.3e-66 224.2 0.2 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KKF93163.1 - 2.3e-41 142.1 0.2 4.8e-41 141.1 0.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KKF93163.1 - 5.7e-33 113.5 0.2 1.3e-32 112.4 0.1 1.7 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KKF93163.1 - 6.4e-13 49.2 0.0 2.4e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KKF93163.1 - 1.1e-10 41.7 0.9 2.3e-10 40.7 0.9 1.6 1 0 0 1 1 1 1 MutS family domain IV DUF577 PF04510.12 KKF93163.1 - 0.01 15.7 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF577) AAA_27 PF13514.6 KKF93163.1 - 0.074 12.6 0.2 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKF93163.1 - 0.087 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KKF93163.1 - 0.24 11.9 0.1 0.24 11.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain FMO-like PF00743.19 KKF93164.1 - 1e-10 40.7 0.0 9.1e-10 37.6 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KKF93164.1 - 3.6e-10 39.9 0.0 1.7e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKF93164.1 - 2e-09 37.1 0.0 6.8e-09 35.4 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKF93164.1 - 7.6e-09 35.2 0.0 2.1e-07 30.5 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKF93164.1 - 4.6e-06 26.0 0.1 0.00011 21.4 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KKF93164.1 - 0.0023 17.9 0.8 2.5 8.1 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 KKF93164.1 - 0.0031 17.2 3.9 0.061 12.9 3.8 2.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 KKF93164.1 - 0.0083 14.7 0.5 0.1 11.1 0.1 2.3 3 0 0 3 3 3 1 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 KKF93164.1 - 0.014 14.6 0.0 0.057 12.6 0.0 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_10 PF13460.6 KKF93164.1 - 0.065 13.1 0.0 0.62 9.9 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H-binding DUF3328 PF11807.8 KKF93165.1 - 2.5e-48 164.8 0.1 3e-48 164.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Retrotran_gag_2 PF14223.6 KKF93167.1 - 0.0022 17.7 0.3 0.0047 16.6 0.3 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KKF93167.1 - 0.0029 17.6 2.4 0.005 16.9 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KKF93167.1 - 0.017 14.8 3.9 0.027 14.2 3.9 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger RNA_binding PF01877.17 KKF93167.1 - 0.083 13.2 1.2 5.4 7.3 0.2 2.5 1 1 1 2 2 2 0 RNA binding Spt5_N PF11942.8 KKF93167.1 - 0.11 13.4 1.9 0.57 11.2 0.2 2.2 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RVT_2 PF07727.14 KKF93168.1 - 1.1e-51 175.8 0.0 1.8e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KKF93168.1 - 2.1e-13 50.5 0.0 5.1e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KKF93168.1 - 0.084 12.7 0.0 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 KKF93169.1 - 5.3e-12 45.8 1.2 1.1e-11 44.8 1.2 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KKF93169.1 - 1.7e-10 40.9 0.0 3.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KKF93169.1 - 6.4e-06 26.4 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KKF93169.1 - 0.031 14.2 0.0 0.096 12.7 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Cpn60_TCP1 PF00118.24 KKF93170.1 - 3.4e-152 507.5 6.0 3.9e-152 507.3 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 KKF93170.1 - 0.19 12.2 0.5 0.78 10.3 0.0 2.2 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch ApoLp-III PF07464.11 KKF93170.1 - 0.58 10.2 6.7 0.18 11.9 0.9 2.9 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) MFS_1 PF07690.16 KKF93171.1 - 1e-34 120.0 30.7 1.6e-34 119.4 30.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3980 PF13140.6 KKF93171.1 - 0.11 13.0 3.5 4.9 7.7 1.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) Glyco_transf_90 PF05686.12 KKF93172.1 - 2.6e-15 56.3 3.8 5.9e-12 45.2 0.1 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 90 RNase_H PF00075.24 KKF93173.1 - 1.3e-07 31.9 0.0 2.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 RNase H PRP38 PF03371.15 KKF93174.1 - 8.5e-57 191.8 0.0 1e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PI3K_1B_p101 PF10486.9 KKF93174.1 - 0.24 9.1 0.7 0.3 8.8 0.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Metallophos PF00149.28 KKF93175.1 - 3e-10 40.9 3.5 5.9e-10 40.0 3.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KKF93175.1 - 6.3e-05 23.2 0.0 0.00016 21.9 0.0 1.7 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain COesterase PF00135.28 KKF93176.1 - 5e-19 68.6 0.0 5.2e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family RXT2_N PF08595.11 KKF93177.1 - 8.3e-40 136.4 3.2 1.2e-39 135.8 0.0 2.4 3 0 0 3 3 3 1 RXT2-like, N-terminal Gryzun PF07919.12 KKF93178.1 - 5.1e-103 345.9 0.0 5.7e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 KKF93178.1 - 2.7e-06 27.3 0.0 5.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking E1-E2_ATPase PF00122.20 KKF93179.1 - 3.3e-48 163.6 0.3 7.4e-48 162.5 0.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KKF93179.1 - 2.1e-30 106.6 0.3 3.5e-30 105.9 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Abhydrolase_6 PF12697.7 KKF93179.1 - 1.1e-10 42.6 2.5 3e-10 41.1 2.5 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKF93179.1 - 2.9e-06 26.7 0.0 6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Hydrolase_3 PF08282.12 KKF93179.1 - 8.4e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKF93179.1 - 0.016 15.6 0.0 0.046 14.1 0.0 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Importin_rep_3 PF18806.1 KKF93179.1 - 0.04 14.0 0.0 0.14 12.2 0.0 2.0 1 0 0 1 1 1 0 Importin 13 repeat Abhydrolase_1 PF00561.20 KKF93179.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KKF93179.1 - 0.058 13.0 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Putative esterase zf-C2H2_2 PF12756.7 KKF93180.1 - 6.7e-27 93.8 4.9 6.7e-26 90.6 0.6 2.8 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KKF93180.1 - 5.3e-06 26.6 5.9 5.3e-06 26.6 5.9 3.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKF93180.1 - 6.5e-05 23.2 4.2 6.5e-05 23.2 4.2 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DEAD PF00270.29 KKF93181.1 - 9.6e-50 168.8 0.0 1.2e-48 165.3 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF93181.1 - 3e-30 104.8 0.0 1.6e-29 102.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF93181.1 - 0.00065 19.7 0.0 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KKF93181.1 - 0.056 13.8 0.0 14 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF5335 PF17269.2 KKF93181.1 - 0.098 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Mpv17_PMP22 PF04117.12 KKF93182.1 - 6.8e-09 35.8 2.7 6.8e-09 35.8 2.7 2.5 2 1 1 3 3 3 1 Mpv17 / PMP22 family Pectate_lyase PF03211.13 KKF93183.1 - 9.3e-81 270.2 8.4 1.1e-80 270.0 8.4 1.0 1 0 0 1 1 1 1 Pectate lyase PDH PF02153.17 KKF93184.1 - 1.3e-14 53.8 0.0 2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KKF93184.1 - 0.031 14.5 0.2 0.081 13.1 0.1 1.7 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KKF93184.1 - 0.079 13.6 0.6 0.77 10.4 0.1 2.5 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KKF93184.1 - 0.11 12.2 0.3 0.47 10.1 0.3 2.1 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA INCENP_ARK-bind PF03941.15 KKF93184.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Rad9 PF04139.13 KKF93185.1 - 1.2e-12 47.9 0.0 1.5e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 Myb_Cef PF11831.8 KKF93186.1 - 2.1e-44 151.9 1.4 2.1e-44 151.9 1.4 3.4 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KKF93186.1 - 2.3e-23 82.1 6.6 1.6e-11 44.2 0.7 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKF93186.1 - 2.8e-19 69.1 4.9 1.8e-13 50.5 2.2 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Tim17 PF02466.19 KKF93186.1 - 2.7e-10 40.6 0.7 6e-10 39.5 0.7 1.6 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Rap1_C PF11626.8 KKF93186.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.7 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain RRM_1 PF00076.22 KKF93187.1 - 1.6e-42 143.1 2.0 1.9e-20 72.4 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 KKF93187.1 - 5.6e-25 88.0 31.6 9.8e-25 87.2 8.6 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily RBM39linker PF15519.6 KKF93187.1 - 1.4e-22 80.5 0.1 5.5e-22 78.7 0.1 2.1 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein HIT PF01230.23 KKF93187.1 - 5.9e-15 55.8 0.1 1.4e-14 54.6 0.1 1.6 1 0 0 1 1 1 1 HIT domain Sugar_tr PF00083.24 KKF93187.1 - 3.2e-09 36.2 0.3 3.2e-09 36.2 0.3 2.8 4 0 0 4 4 3 1 Sugar (and other) transporter RRM_occluded PF16842.5 KKF93187.1 - 0.002 18.0 0.0 1.1 9.2 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KKF93187.1 - 0.0085 16.1 1.0 0.073 13.1 0.0 2.7 3 0 0 3 3 3 1 RNA binding motif DcpS_C PF11969.8 KKF93187.1 - 0.018 15.5 0.0 0.09 13.3 0.0 2.0 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding PHM7_cyt PF14703.6 KKF93187.1 - 0.086 13.1 0.1 0.37 11.0 0.1 2.3 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KKF93187.1 - 0.15 12.1 0.0 3.3 7.8 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF3487 PF11990.8 KKF93187.1 - 0.92 9.4 0.0 0.92 9.4 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3487) Aminotran_1_2 PF00155.21 KKF93188.1 - 2.6e-36 125.6 0.0 3.4e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II VWA PF00092.28 KKF93189.1 - 9.1e-07 29.3 0.0 1.3e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KKF93189.1 - 0.0028 18.3 0.0 0.0057 17.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KKF93189.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 vWA found in TerF C terminus Memo PF01875.17 KKF93192.1 - 5e-70 235.7 0.0 7.8e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Memo-like protein TFIIA PF03153.13 KKF93192.1 - 6.9 6.6 11.1 9.8 6.0 11.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Syntaxin PF00804.25 KKF93193.1 - 1.6e-19 70.4 11.9 1.6e-19 70.4 11.9 2.0 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 KKF93193.1 - 3.1e-10 39.9 2.9 1.1e-09 38.1 2.9 2.1 1 0 0 1 1 1 1 SNARE domain ODV-E18 PF10717.9 KKF93193.1 - 0.00016 21.5 0.1 0.00044 20.1 0.1 1.7 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 Synaptobrevin PF00957.21 KKF93193.1 - 0.0059 16.4 3.4 0.0059 16.4 3.4 2.4 2 0 0 2 2 2 1 Synaptobrevin SLATT_5 PF18160.1 KKF93193.1 - 0.0068 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 DUF3328 PF11807.8 KKF93193.1 - 0.015 15.0 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) CrgA PF06781.12 KKF93193.1 - 0.032 14.3 0.1 0.088 12.9 0.1 1.7 1 0 0 1 1 1 0 Cell division protein CrgA Saf_2TM PF18303.1 KKF93193.1 - 0.036 13.7 0.8 4.9 6.7 0.2 2.3 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Vac_Fusion PF02346.16 KKF93193.1 - 0.053 13.2 4.2 9.3 6.0 0.0 3.4 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF2207 PF09972.9 KKF93193.1 - 0.19 10.4 1.4 0.28 9.9 0.2 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 KKF93193.1 - 0.28 11.5 2.1 0.51 10.7 0.3 2.3 2 0 0 2 2 2 0 Orf78 (ac78) PIG-P PF08510.12 KKF93193.1 - 0.46 10.4 1.4 1.3 9.0 1.4 1.7 1 0 0 1 1 1 0 PIG-P Allexi_40kDa PF05549.11 KKF93193.1 - 0.63 9.5 6.8 0.67 9.4 0.6 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein MCU PF04678.13 KKF93193.1 - 0.69 10.0 8.8 0.26 11.4 1.7 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter TMCO5 PF14992.6 KKF93193.1 - 1.3 8.5 11.3 46 3.5 11.3 2.1 1 1 0 1 1 1 0 TMCO5 family RIFIN PF02009.16 KKF93193.1 - 1.4 8.7 12.8 8.4 6.2 12.8 2.1 1 1 0 1 1 1 0 Rifin FUSC PF04632.12 KKF93193.1 - 2.3 6.7 15.4 2 6.9 7.5 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family EMP24_GP25L PF01105.24 KKF93193.1 - 3.1 7.7 9.8 0.98 9.3 4.4 2.7 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD BLOC1_2 PF10046.9 KKF93193.1 - 3.6 7.9 10.7 1.5 9.2 1.7 3.8 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.13 KKF93193.1 - 5.2 7.9 6.3 9.5 7.0 0.2 2.9 2 1 1 3 3 3 0 Occludin homology domain DUF4709 PF15821.5 KKF93193.1 - 5.4 7.3 11.4 17 5.7 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) zf-CpG_bind_C PF12269.8 KKF93193.1 - 7.4 6.3 10.5 11 5.7 2.6 2.4 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain WD40 PF00400.32 KKF93195.1 - 7.1e-10 39.3 9.8 2.7 9.0 0.2 8.6 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF93195.1 - 1e-06 28.9 0.5 0.085 13.2 0.0 5.5 4 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF93195.1 - 0.047 12.6 0.1 1.3 7.9 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hydro_30C PF17189.4 KKF93195.1 - 0.38 11.0 4.5 2 8.7 0.3 3.0 3 0 0 3 3 3 0 Glycosyl hydrolase family 30 beta sandwich domain Rad4 PF03835.15 KKF93196.1 - 2.6e-13 49.9 6.1 6.1e-13 48.7 6.1 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain UPF0492 PF15744.5 KKF93196.1 - 0.035 13.3 1.2 0.052 12.8 1.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 2OG-FeII_Oxy_2 PF13532.6 KKF93196.1 - 0.055 13.6 0.3 0.17 12.0 0.1 2.0 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Cerato-platanin PF07249.12 KKF93197.1 - 1.8e-32 112.0 0.4 2.1e-32 111.7 0.4 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 KKF93197.1 - 0.0016 18.3 0.3 0.0025 17.7 0.3 1.5 1 1 0 1 1 1 1 Barwin family Sec7 PF01369.20 KKF93198.1 - 4.3e-26 91.7 0.0 9.7e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KKF93198.1 - 2.7e-19 69.7 0.0 6.8e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain HA2 PF04408.23 KKF93200.1 - 1.9e-16 60.3 0.0 1.9e-16 60.3 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKF93200.1 - 5.3e-13 49.3 0.0 1.3e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KKF93200.1 - 1.8e-10 41.0 0.0 4.5e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KKF93200.1 - 9.5e-07 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKF93200.1 - 2e-06 28.1 0.2 8.7e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KKF93200.1 - 0.034 13.2 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KKF93200.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain XhlA PF10779.9 KKF93200.1 - 0.12 12.6 0.6 0.37 11.0 0.6 1.9 1 0 0 1 1 1 0 Haemolysin XhlA ABC_tran PF00005.27 KKF93200.1 - 1.1 9.8 0.0 1.1 9.8 0.0 2.9 2 1 0 2 2 2 0 ABC transporter Laminin_II PF06009.12 KKF93200.1 - 1.1 9.2 7.3 1.7 8.7 1.3 2.6 2 0 0 2 2 2 0 Laminin Domain II Rab5ip PF07019.12 KKF93201.1 - 6.2e-29 100.4 6.5 7.3e-29 100.2 6.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Vezatin PF12632.7 KKF93202.1 - 5.9e-71 239.1 0.1 1.1e-70 238.3 0.1 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Cyclin_N PF00134.23 KKF93204.1 - 2.2e-13 50.1 0.0 3.4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KKF93204.1 - 1.2e-06 29.0 0.0 3.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Cyclin DUF3824 PF12868.7 KKF93204.1 - 0.0046 17.6 7.5 0.0087 16.7 7.5 1.6 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) Hormone_3 PF00159.18 KKF93205.1 - 0.0069 16.4 9.7 6.1 7.0 0.1 5.2 5 0 0 5 5 5 4 Pancreatic hormone peptide MatE PF01554.18 KKF93206.1 - 5.5e-54 182.2 25.1 2e-33 115.3 8.6 2.8 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 KKF93206.1 - 0.009 16.1 11.1 0.009 16.1 11.1 3.8 3 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Pet100 PF09803.9 KKF93206.1 - 0.41 11.2 1.1 1.1 9.8 1.1 1.6 1 0 0 1 1 1 0 Pet100 Tam41_Mmp37 PF09139.11 KKF93207.1 - 9.4e-124 413.0 0.0 1.3e-123 412.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial SLATT_fungal PF18142.1 KKF93207.1 - 6.2e-23 81.1 0.1 1.2e-22 80.1 0.1 1.5 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain VHP PF02209.19 KKF93207.1 - 0.081 13.0 0.2 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 Villin headpiece domain Glyco_transf_22 PF03901.17 KKF93208.1 - 2.3e-77 261.0 27.1 2.7e-77 260.8 27.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.14 KKF93209.1 - 1.5e-45 154.7 0.1 1.5e-45 154.7 0.1 2.7 3 1 1 4 4 4 1 Gar1/Naf1 RNA binding region Cwf_Cwc_15 PF04889.12 KKF93209.1 - 3.6 7.2 29.4 0.61 9.8 21.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.9 KKF93209.1 - 8.5 4.8 12.0 1.5 7.3 5.3 2.0 2 0 0 2 2 2 0 Macoilin family SH3_9 PF14604.6 KKF93210.1 - 5.5e-10 38.9 0.0 8.8e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKF93210.1 - 9.1e-07 28.4 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKF93210.1 - 7.8e-06 25.5 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF5305 PF17231.2 KKF93210.1 - 0.031 13.7 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Amnionless PF14828.6 KKF93210.1 - 0.058 12.2 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4366 PF14283.6 KKF93210.1 - 0.13 12.3 0.7 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) SKG6 PF08693.10 KKF93210.1 - 0.14 11.6 0.1 0.38 10.2 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.16 KKF93210.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MtrF PF09472.10 KKF93210.1 - 0.59 9.6 2.3 1.1 8.7 2.3 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Mito_carr PF00153.27 KKF93211.1 - 5e-56 186.6 3.8 2.2e-18 65.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.22 KKF93212.1 - 0.00014 21.6 0.0 1.3 8.7 0.0 3.3 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Peptidase_C13 PF01650.18 KKF93213.1 - 3.3e-39 134.9 0.1 4.8e-39 134.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.7 KKF93213.1 - 1.8e-17 63.8 0.1 5.1e-17 62.4 0.0 1.7 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term SR-25 PF10500.9 KKF93213.1 - 0.018 14.6 9.4 0.037 13.6 9.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CoA_binding_2 PF13380.6 KKF93214.1 - 1.2e-25 90.2 0.1 2.3e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 CoA binding domain TP_methylase PF00590.20 KKF93215.1 - 9.8e-22 77.9 0.1 1.8e-21 77.1 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.8 KKF93216.1 - 6.8e-07 29.4 0.1 1.3e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKF93216.1 - 2.2e-05 24.7 0.1 4e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KKF93216.1 - 0.0008 19.7 0.3 0.0014 19.0 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type SNRNP27 PF08648.12 KKF93216.1 - 0.0013 18.7 0.6 0.0013 18.7 0.6 2.0 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 KKF93216.1 - 0.008 16.3 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_4 PF13894.6 KKF93216.1 - 0.011 16.5 0.1 0.02 15.7 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KKF93216.1 - 0.015 15.6 0.1 0.031 14.6 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) UQ_con PF00179.26 KKF93217.1 - 2.4e-37 127.7 0.0 2.7e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKF93217.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B Glyco_trans_1_4 PF13692.6 KKF93218.1 - 3.1e-07 30.9 0.0 3.6e-06 27.5 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KKF93218.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Cation_efflux PF01545.21 KKF93219.1 - 3.4e-46 157.5 6.7 4.4e-46 157.1 6.7 1.1 1 0 0 1 1 1 1 Cation efflux family DUF5134 PF17197.4 KKF93219.1 - 0.024 14.6 0.3 0.024 14.6 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) EF-hand_7 PF13499.6 KKF93220.1 - 2.9e-13 50.1 0.3 2.4e-08 34.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KKF93220.1 - 3.8e-12 46.3 0.0 1.3e-05 25.4 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KKF93220.1 - 7.7e-10 37.9 0.2 0.0059 16.4 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KKF93220.1 - 2.1e-09 36.2 0.1 0.015 14.8 0.0 3.7 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KKF93220.1 - 3.8e-08 33.1 0.1 8.1e-05 22.4 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_14 PF17959.1 KKF93220.1 - 0.093 13.1 0.0 7.5 7.0 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Peptidase_M3 PF01432.20 KKF93221.1 - 5.9e-152 507.1 0.0 8.1e-152 506.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KKF93221.1 - 0.065 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Effector protein BIR PF00653.21 KKF93222.1 - 9.3e-25 87.1 0.0 4.1e-18 65.8 0.0 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain DUF5446 PF17522.2 KKF93222.1 - 3.1 8.0 5.1 0.87 9.8 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5446) MFS_1 PF07690.16 KKF93223.1 - 1.4e-33 116.3 31.2 1.4e-33 116.3 31.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 KKF93223.1 - 0.46 10.8 10.4 1.9 8.8 4.3 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF1772) Phage_holin_3_6 PF07332.11 KKF93223.1 - 0.79 9.8 5.8 0.64 10.1 0.6 2.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DEAD PF00270.29 KKF93224.1 - 4e-40 137.5 0.0 1e-39 136.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF93224.1 - 1.9e-24 86.1 0.0 5e-24 84.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF93224.1 - 0.00026 21.1 0.0 0.00089 19.3 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KKF93224.1 - 0.012 15.9 0.9 0.062 13.6 0.1 2.7 3 1 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KKF93226.1 - 0.0001 22.2 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain TPR_MLP1_2 PF07926.12 KKF93227.1 - 2.3e-37 128.0 28.6 2.3e-37 128.0 28.6 19.1 7 6 13 20 20 20 4 TPR/MLP1/MLP2-like protein FlxA PF14282.6 KKF93227.1 - 0.0012 18.8 7.5 0.0012 18.8 7.5 20.7 11 5 9 20 20 20 1 FlxA-like protein GAS PF13851.6 KKF93227.1 - 0.0021 17.5 9.6 0.0021 17.5 9.6 17.0 7 5 7 16 16 16 7 Growth-arrest specific micro-tubule binding ABC_tran_CTD PF16326.5 KKF93227.1 - 0.0064 16.7 0.6 0.0064 16.7 0.6 21.7 15 7 8 23 23 23 2 ABC transporter C-terminal domain APG6_N PF17675.1 KKF93227.1 - 0.008 16.7 14.2 0.008 16.7 14.2 18.3 4 3 14 19 19 19 2 Apg6 coiled-coil region Viral_DNA_bi PF02236.17 KKF93227.1 - 0.3 11.3 2.9 3.4 7.9 0.2 3.1 3 0 0 3 3 3 0 Viral DNA-binding protein, all alpha domain Pox_A_type_inc PF04508.12 KKF93227.1 - 1.2 9.1 0.0 1.2 9.1 0.0 8.9 9 1 0 9 9 9 0 Viral A-type inclusion protein repeat PLAC9 PF15205.6 KKF93227.1 - 1.3 9.5 4.1 3.8 8.0 0.1 4.0 5 0 0 5 5 5 0 Placenta-specific protein 9 DegQ PF08181.11 KKF93227.1 - 5.9 7.1 8.8 4.8 7.4 3.9 3.7 2 0 0 2 2 2 0 DegQ (SacQ) family CDH-cyt PF16010.5 KKF93228.1 - 2.2e-61 206.7 3.6 4.7e-60 202.4 3.1 2.3 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KKF93228.1 - 1.8e-26 93.2 0.0 4e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKF93228.1 - 2e-23 83.5 0.6 3.6e-23 82.7 0.6 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKF93228.1 - 5e-10 39.0 0.0 1.4e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KKF93228.1 - 6.2e-05 23.2 0.0 0.00019 21.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKF93228.1 - 0.00086 18.1 0.0 0.0027 16.5 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KKF93228.1 - 0.001 18.4 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKF93228.1 - 0.0043 16.3 0.1 0.012 14.9 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKF93228.1 - 0.0089 15.1 0.7 0.012 14.7 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KKF93228.1 - 0.011 15.0 0.1 2.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 KKF93228.1 - 0.013 14.7 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KKF93228.1 - 0.016 14.6 0.0 0.75 9.1 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KKF93228.1 - 0.028 15.0 0.0 0.74 10.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sporozoite_P67 PF05642.11 KKF93228.1 - 6.6 4.7 8.7 19 3.1 7.7 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CFEM PF05730.11 KKF93229.1 - 0.0011 19.0 2.4 0.0019 18.2 2.4 1.4 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 KKF93229.1 - 0.0045 16.4 0.0 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Apt1 PF10351.9 KKF93229.1 - 2.7 6.7 8.2 3.3 6.5 8.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hamartin PF04388.12 KKF93229.1 - 6.6 5.3 12.7 11 4.6 12.7 1.3 1 0 0 1 1 1 0 Hamartin protein Glyco_hydro_61 PF03443.14 KKF93231.1 - 2.9e-59 200.5 0.2 4.2e-59 199.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sortilin-Vps10 PF15902.5 KKF93232.1 - 2.2e-19 69.6 3.2 1.3e-07 30.8 0.0 4.9 3 1 0 4 4 4 4 Sortilin, neurotensin receptor 3, BNR PF02012.20 KKF93232.1 - 6.8e-09 34.4 36.8 0.33 11.1 0.4 9.9 9 0 0 9 9 9 6 BNR/Asp-box repeat CBM_1 PF00734.18 KKF93232.1 - 1.8e-07 30.9 4.3 4.6e-07 29.7 4.3 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR_6 PF15899.5 KKF93232.1 - 0.036 14.1 14.3 9.8 6.6 0.0 7.0 7 0 0 7 7 7 0 BNR-Asp box repeat BNR_3 PF13859.6 KKF93232.1 - 0.044 13.1 6.9 5.8 6.1 0.0 4.5 4 1 0 4 4 4 0 BNR repeat-like domain BNR_2 PF13088.6 KKF93232.1 - 0.051 12.9 14.3 20 4.4 0.1 6.1 4 2 0 4 4 4 0 BNR repeat-like domain Kelch_3 PF13415.6 KKF93232.1 - 0.13 12.6 4.0 0.29 11.5 0.3 3.9 3 0 0 3 3 3 0 Galactose oxidase, central domain LUC7 PF03194.15 KKF93233.1 - 7.4e-50 170.0 5.6 4e-49 167.5 1.7 2.0 1 1 1 2 2 2 1 LUC7 N_terminus MCPsignal PF00015.21 KKF93233.1 - 0.0038 17.0 0.1 0.0066 16.3 0.1 1.4 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Golgin_A5 PF09787.9 KKF93233.1 - 0.019 14.4 2.1 0.028 13.9 2.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3418 PF11898.8 KKF93233.1 - 0.02 13.6 0.5 0.023 13.4 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Spc7 PF08317.11 KKF93233.1 - 0.042 12.7 1.0 0.052 12.4 1.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec8_exocyst PF04048.14 KKF93233.1 - 0.053 13.4 0.5 0.13 12.2 0.3 1.6 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain FliJ PF02050.16 KKF93233.1 - 0.059 13.6 2.4 0.076 13.2 0.6 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein Aida_N PF08910.10 KKF93233.1 - 0.061 13.7 0.9 1.8 9.0 0.1 2.6 3 0 0 3 3 3 0 Aida N-terminus DUF4600 PF15372.6 KKF93233.1 - 0.1 13.0 3.2 0.44 11.0 0.8 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4600) DUF4686 PF15742.5 KKF93233.1 - 0.22 10.6 3.6 0.18 10.9 0.8 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) Gpi16 PF04113.14 KKF93234.1 - 4.2e-217 722.0 0.0 3.3e-125 418.7 0.0 2.0 1 1 1 2 2 2 2 Gpi16 subunit, GPI transamidase component FAM176 PF14851.6 KKF93235.1 - 0.003 17.2 8.4 0.0034 17.0 8.4 1.0 1 0 0 1 1 1 1 FAM176 family Connexin PF00029.19 KKF93235.1 - 0.0035 17.1 14.3 0.0035 17.1 14.3 1.0 1 0 0 1 1 1 1 Connexin NPR3 PF03666.13 KKF93235.1 - 0.0045 15.9 10.5 0.0045 15.9 10.5 1.0 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 PRC2_HTH_1 PF18118.1 KKF93235.1 - 0.018 15.8 14.6 0.02 15.7 14.6 1.1 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain CPSF100_C PF13299.6 KKF93235.1 - 0.021 15.0 11.8 0.022 14.9 11.8 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MRP-S25 PF13741.6 KKF93235.1 - 0.022 14.3 12.0 0.022 14.3 12.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 PcfK PF14058.6 KKF93235.1 - 0.027 14.8 22.5 0.029 14.7 22.5 1.1 1 0 0 1 1 1 0 PcfK-like protein DOCK_N PF16172.5 KKF93235.1 - 0.029 13.3 6.9 0.031 13.2 6.9 1.0 1 0 0 1 1 1 0 DOCK N-terminus RPN2_C PF18004.1 KKF93235.1 - 0.034 14.1 26.0 0.035 14.0 26.0 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Eapp_C PF10238.9 KKF93235.1 - 0.067 13.3 12.8 0.079 13.0 12.8 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein Tim54 PF11711.8 KKF93235.1 - 0.081 11.7 16.5 0.089 11.6 16.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 KKF93235.1 - 0.084 12.7 20.1 0.093 12.5 20.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peroxin-13_N PF04088.13 KKF93235.1 - 0.096 13.0 6.8 0.1 12.9 6.8 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region EIIBC-GUT_N PF03612.14 KKF93235.1 - 0.12 12.1 10.9 0.14 11.9 10.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TRAP_alpha PF03896.16 KKF93235.1 - 0.14 11.4 4.8 0.15 11.3 4.8 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PTPRCAP PF15713.5 KKF93235.1 - 0.18 12.1 10.6 0.2 11.9 10.6 1.0 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4337 PF14235.6 KKF93235.1 - 0.19 11.8 12.6 0.2 11.8 12.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Afi1 PF07792.12 KKF93235.1 - 0.22 12.0 9.6 0.25 11.8 9.6 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SpoIIP PF07454.11 KKF93235.1 - 0.29 10.5 16.5 0.33 10.4 16.5 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 KKF93235.1 - 0.3 11.2 14.0 0.33 11.1 14.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.12 KKF93235.1 - 0.33 9.9 8.3 0.3 10.0 8.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3408 PF11888.8 KKF93235.1 - 0.37 10.9 20.4 0.44 10.7 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RNA_pol_Rpc4 PF05132.14 KKF93235.1 - 0.41 11.1 18.2 0.48 10.8 18.2 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 Folate_carrier PF01770.18 KKF93235.1 - 0.41 9.3 8.6 0.44 9.2 8.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier AIF_C PF14721.6 KKF93235.1 - 0.42 11.0 11.4 0.47 10.8 11.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2828 PF11443.8 KKF93235.1 - 0.45 8.5 17.9 0.48 8.4 17.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) V_ATPase_I PF01496.19 KKF93235.1 - 0.46 8.4 12.2 0.49 8.3 12.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFB6 PF17110.5 KKF93235.1 - 0.47 10.2 8.2 0.53 10.0 8.2 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DDHD PF02862.17 KKF93235.1 - 0.47 10.6 9.1 0.5 10.5 9.1 1.0 1 0 0 1 1 1 0 DDHD domain CLN3 PF02487.17 KKF93235.1 - 0.51 9.3 8.4 0.56 9.2 8.4 1.0 1 0 0 1 1 1 0 CLN3 protein Rxt3 PF08642.10 KKF93235.1 - 0.57 11.0 7.3 0.72 10.6 7.3 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 FemAB PF02388.16 KKF93235.1 - 0.59 9.0 14.7 0.65 8.8 14.7 1.0 1 0 0 1 1 1 0 FemAB family DUF4834 PF16118.5 KKF93235.1 - 0.66 11.0 12.3 0.76 10.8 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pal1 PF08316.11 KKF93235.1 - 0.7 10.6 5.1 0.73 10.6 5.1 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein RPA43_OB PF17875.1 KKF93235.1 - 0.73 10.5 8.9 0.99 10.0 8.9 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I PDCD2_C PF04194.13 KKF93235.1 - 0.76 9.8 12.9 0.81 9.7 12.9 1.0 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain EOS1 PF12326.8 KKF93235.1 - 0.76 9.7 8.2 0.79 9.6 8.2 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF3464 PF11947.8 KKF93235.1 - 0.79 9.5 18.5 0.92 9.2 18.5 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 KKF93235.1 - 0.79 8.4 12.2 0.85 8.3 12.2 1.0 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 KKF93235.1 - 0.8 10.0 27.7 0.95 9.8 27.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SLC12 PF03522.15 KKF93235.1 - 0.83 8.6 12.4 0.88 8.5 12.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CSG2 PF16965.5 KKF93235.1 - 0.84 8.5 6.4 0.86 8.5 6.4 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator OATP PF03137.20 KKF93235.1 - 0.84 7.8 10.0 0.82 7.9 10.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Otopetrin PF03189.13 KKF93235.1 - 0.89 8.3 5.6 0.91 8.3 5.6 1.0 1 0 0 1 1 1 0 Otopetrin DUF4228 PF14009.6 KKF93235.1 - 0.92 9.9 9.9 1.1 9.7 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF5308 PF17233.2 KKF93235.1 - 0.94 9.7 4.7 0.98 9.6 4.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SspB PF04386.13 KKF93235.1 - 0.94 9.3 12.1 1 9.2 12.1 1.1 1 0 0 1 1 1 0 Stringent starvation protein B CobT PF06213.12 KKF93235.1 - 0.96 8.8 12.0 1 8.7 12.0 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Kei1 PF08552.11 KKF93235.1 - 1 9.2 3.0 1.1 9.2 3.0 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DcuA_DcuB PF03605.14 KKF93235.1 - 1.1 8.1 5.6 1.1 8.1 5.6 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Ureide_permease PF07168.11 KKF93235.1 - 1.1 7.9 8.7 1.2 7.8 8.7 1.0 1 0 0 1 1 1 0 Ureide permease Zip PF02535.22 KKF93235.1 - 1.2 8.3 9.5 1.3 8.2 9.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3807 PF12720.7 KKF93235.1 - 1.3 9.3 21.8 1.5 9.1 21.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) HSP90 PF00183.18 KKF93235.1 - 1.3 7.9 21.0 1.4 7.7 21.0 1.0 1 0 0 1 1 1 0 Hsp90 protein ALMT PF11744.8 KKF93235.1 - 1.4 7.7 10.2 1.5 7.5 10.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter GNAT_acetyltr_2 PF13718.6 KKF93235.1 - 1.5 8.2 9.3 1.6 8.1 9.3 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 BSMAP PF12280.8 KKF93235.1 - 1.5 9.0 7.6 1.9 8.6 7.6 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein Sec62 PF03839.16 KKF93235.1 - 1.5 8.3 20.5 2.1 7.8 20.5 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RP-C_C PF11800.8 KKF93235.1 - 1.5 8.8 7.2 1.8 8.6 7.2 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Serinc PF03348.15 KKF93235.1 - 1.6 7.6 6.5 1.6 7.5 6.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_11 PF13086.6 KKF93235.1 - 1.6 8.4 14.5 1.6 8.4 14.5 1.0 1 0 0 1 1 1 0 AAA domain PPL5 PF18168.1 KKF93235.1 - 1.7 7.9 14.4 1.9 7.7 14.4 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Band_3_cyto PF07565.13 KKF93235.1 - 1.8 8.3 9.3 2 8.2 9.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MCM_bind PF09739.9 KKF93235.1 - 1.8 6.9 13.2 2 6.8 13.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MCU PF04678.13 KKF93235.1 - 1.8 8.6 7.6 1.9 8.6 7.6 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Paramyxo_ncap PF00973.19 KKF93235.1 - 1.9 7.3 9.6 2 7.3 9.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Peptidase_C37 PF05416.12 KKF93235.1 - 1.9 6.9 15.4 2 6.8 15.4 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase G0-G1_switch_2 PF15103.6 KKF93235.1 - 1.9 9.0 14.4 2.3 8.7 14.4 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF789 PF05623.12 KKF93235.1 - 2.4 7.8 8.2 2.5 7.7 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Dynamin_N PF00350.23 KKF93235.1 - 2.4 8.2 9.4 2.5 8.1 9.4 1.0 1 0 0 1 1 1 0 Dynamin family Noggin PF05806.12 KKF93235.1 - 2.4 8.0 11.3 2.6 7.9 11.3 1.0 1 0 0 1 1 1 0 Noggin Peptidase_U57 PF05582.12 KKF93235.1 - 2.4 7.3 11.0 2.6 7.3 11.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 ORC_WH_C PF18137.1 KKF93235.1 - 2.7 8.1 17.1 3.4 7.7 17.1 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF3438 PF11920.8 KKF93235.1 - 2.8 7.1 6.2 2.9 7.0 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Coilin_N PF15862.5 KKF93235.1 - 2.8 7.7 28.4 3.4 7.5 28.4 1.1 1 0 0 1 1 1 0 Coilin N-terminus MAP17 PF15807.5 KKF93235.1 - 2.9 8.2 18.6 3.5 7.9 18.6 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 GAGA_bind PF06217.12 KKF93235.1 - 2.9 8.1 22.3 3.2 8.0 22.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family RPOL_N PF14700.6 KKF93235.1 - 3 7.2 16.9 3.1 7.1 16.9 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal FHIPEP PF00771.20 KKF93235.1 - 3 6.2 6.1 3.1 6.1 6.1 1.1 1 0 0 1 1 1 0 FHIPEP family Ctr PF04145.15 KKF93235.1 - 3.1 8.4 4.6 3.4 8.3 4.6 1.1 1 0 0 1 1 1 0 Ctr copper transporter family LicD PF04991.13 KKF93235.1 - 3.2 7.8 14.0 3.7 7.6 14.0 1.0 1 0 0 1 1 1 0 LicD family DUF1764 PF08576.10 KKF93235.1 - 3.4 8.6 26.2 4.4 8.3 26.2 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) SRP-alpha_N PF04086.13 KKF93235.1 - 3.6 7.4 23.0 3.8 7.4 23.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal AF-4 PF05110.13 KKF93235.1 - 3.8 5.5 29.4 4.5 5.2 29.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SID-1_RNA_chan PF13965.6 KKF93235.1 - 3.9 5.8 5.9 4.1 5.7 5.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2126 PF09899.9 KKF93235.1 - 4.1 5.4 8.3 4.5 5.2 8.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Neur_chan_memb PF02932.16 KKF93235.1 - 4.5 7.2 10.0 4.7 7.2 10.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FPN1 PF06963.12 KKF93235.1 - 4.6 5.7 5.1 6.1 5.3 5.1 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3405 PF11885.8 KKF93235.1 - 4.8 5.7 15.1 5.1 5.6 15.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Nucleoside_tran PF01733.18 KKF93235.1 - 4.8 6.5 5.7 5.1 6.4 5.7 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF4770 PF15994.5 KKF93235.1 - 5.4 7.2 17.0 7.4 6.8 17.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) MscS_TM PF12794.7 KKF93235.1 - 7.2 5.4 8.3 7.7 5.3 8.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 NARP1 PF12569.8 KKF93235.1 - 7.3 5.4 28.4 8.6 5.1 28.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EMC3_TMCO1 PF01956.16 KKF93235.1 - 7.5 6.3 14.5 8.9 6.0 14.5 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Fmp27 PF10344.9 KKF93235.1 - 7.8 4.4 14.6 7.6 4.5 14.6 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Sugar_tr PF00083.24 KKF93235.1 - 7.9 5.2 7.8 8.5 5.1 7.8 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter CDC45 PF02724.14 KKF93235.1 - 9.5 4.4 20.1 10 4.2 20.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Membralin PF09746.9 KKF93235.1 - 9.9 5.1 9.0 10 5.0 9.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein Bap31_Bap29_C PF18035.1 KKF93236.1 - 0.0085 16.1 5.0 0.0085 16.1 5.0 12.2 9 7 3 12 12 12 3 Bap31/Bap29 cytoplasmic coiled-coil domain Filament PF00038.21 KKF93236.1 - 0.061 12.9 136.2 0.049 13.2 6.3 7.7 1 1 4 6 6 6 0 Intermediate filament protein PKcGMP_CC PF16808.5 KKF93236.1 - 0.39 10.6 31.2 0.6 10.0 0.7 7.2 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase p450 PF00067.22 KKF93237.1 - 1.3e-57 195.6 0.0 1.6e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Patched PF02460.18 KKF93238.1 - 5.6e-72 243.0 23.4 6.8e-49 166.7 3.0 2.4 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KKF93238.1 - 5e-50 169.3 8.2 5e-50 169.3 8.2 3.4 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 KKF93238.1 - 5.7e-39 134.1 0.9 7.8e-39 133.7 0.9 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus MMPL PF03176.15 KKF93238.1 - 0.00016 20.7 10.5 0.00016 20.7 10.5 3.6 3 1 0 3 3 3 1 MMPL family Cation_ATPase_C PF00689.21 KKF93239.1 - 7.4e-40 136.6 8.4 7.4e-40 136.6 8.4 3.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KKF93239.1 - 1.7e-39 135.2 13.3 2.4e-39 134.7 3.3 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 KKF93239.1 - 1.8e-22 80.7 0.1 9.6e-11 42.4 0.2 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKF93239.1 - 4.8e-11 42.6 0.0 1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KKF93239.1 - 6.7e-11 41.7 0.0 1.6e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKF93239.1 - 9.1e-05 22.3 0.3 0.0002 21.2 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKF93239.1 - 0.046 14.1 0.0 0.36 11.2 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 KKF93239.1 - 0.067 13.0 7.1 0.079 12.7 0.0 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) DUF2231 PF09990.9 KKF93239.1 - 3 8.3 8.4 0.61 10.6 0.8 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) Amidase PF01425.21 KKF93240.1 - 2.5e-72 244.3 0.0 3e-70 237.4 0.0 2.1 1 1 0 1 1 1 1 Amidase SoxE PF06525.11 KKF93240.1 - 0.11 11.9 0.0 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 Sulfocyanin (SoxE) domain F-box PF00646.33 KKF93241.1 - 6.3e-07 29.1 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KKF93241.1 - 5.1e-05 23.1 0.1 0.00024 20.9 0.0 2.3 2 1 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KKF93241.1 - 0.0097 15.8 0.0 0.029 14.2 0.0 1.8 2 0 0 2 2 2 1 F-box CUE PF02845.16 KKF93242.1 - 3.7e-05 23.3 0.0 9.2e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain Smr PF01713.21 KKF93242.1 - 0.01 16.2 0.0 0.087 13.2 0.0 2.4 2 0 0 2 2 2 0 Smr domain DMA PF03474.14 KKF93242.1 - 0.07 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif Phage-tail_3 PF13550.6 KKF93242.1 - 0.23 11.3 1.7 0.62 9.9 0.7 1.9 1 1 1 2 2 2 0 Putative phage tail protein Leuk-A4-hydro_C PF09127.11 KKF93242.1 - 0.59 10.2 3.4 18 5.4 0.0 3.2 2 1 1 3 3 3 0 Leukotriene A4 hydrolase, C-terminal PEX11 PF05648.14 KKF93243.1 - 1.9e-16 60.2 4.1 5.7e-14 52.1 4.1 3.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) YL1 PF05764.13 KKF93243.1 - 0.00046 20.4 2.1 0.00061 20.0 2.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Nop53 PF07767.11 KKF93243.1 - 0.02 14.3 5.7 0.027 13.9 5.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 KKF93243.1 - 0.039 12.2 3.5 0.058 11.7 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 KKF93243.1 - 0.06 13.3 1.6 0.12 12.3 1.6 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PTPRCAP PF15713.5 KKF93243.1 - 0.13 12.6 5.5 0.12 12.7 3.2 1.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated XAP5 PF04921.14 KKF93243.1 - 0.6 9.9 5.4 0.89 9.3 5.4 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator RR_TM4-6 PF06459.12 KKF93243.1 - 6.8 6.4 6.9 9.9 5.9 6.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Complex1_51K PF01512.17 KKF93244.1 - 1.3e-47 161.5 0.0 2e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KKF93244.1 - 2.3e-29 101.3 0.1 4e-29 100.5 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KKF93244.1 - 6.1e-08 32.4 0.1 4.3e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 SLBB domain Hexapep PF00132.24 KKF93245.1 - 2.4e-14 52.4 13.8 1.7e-08 33.8 4.1 4.3 3 2 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKF93245.1 - 0.018 14.8 15.1 0.1 12.3 6.3 3.3 1 1 3 4 4 4 0 Hexapeptide repeat of succinyl-transferase BLM10_mid PF16507.5 KKF93246.1 - 2.7e-189 630.2 0.0 4.2e-189 629.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KKF93246.1 - 3.3e-29 100.6 0.0 1.5e-28 98.6 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KKF93246.1 - 3.2e-13 49.8 0.0 9.8e-13 48.2 0.0 1.9 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 KKF93246.1 - 0.0012 19.0 0.1 1.1 9.7 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 KKF93246.1 - 0.01 15.4 0.4 0.61 9.6 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal Velvet PF11754.8 KKF93248.1 - 4.5e-43 148.0 27.9 5.9e-32 111.6 1.3 4.1 3 1 1 4 4 4 3 Velvet factor Methyltransf_23 PF13489.6 KKF93249.1 - 4.5e-07 29.9 0.0 6.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF93249.1 - 0.089 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M48 PF01435.18 KKF93250.1 - 5.6e-34 117.6 0.0 7.4e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 UTP15_C PF09384.10 KKF93251.1 - 1.6e-50 170.6 0.4 2.4e-50 170.0 0.4 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KKF93251.1 - 5.6e-17 61.8 5.9 0.00012 22.8 0.1 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF93251.1 - 1.3e-06 28.7 0.1 0.18 12.2 0.0 4.9 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKF93251.1 - 0.03 13.0 1.3 4.2 5.9 0.4 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 MMR_HSR1_C PF08438.10 KKF93253.1 - 1.1e-35 122.6 0.0 2.9e-35 121.2 0.0 1.7 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KKF93253.1 - 5.2e-21 74.9 0.0 2e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKF93253.1 - 1.3e-09 37.8 0.1 1.8e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KKF93253.1 - 0.0055 16.3 0.2 1.4 8.5 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KKF93253.1 - 0.012 15.7 1.1 0.17 12.0 0.2 2.6 3 0 0 3 3 3 0 Dynamin family MMR_HSR1_Xtn PF16897.5 KKF93253.1 - 0.016 15.2 0.2 0.037 14.0 0.2 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 KKF93253.1 - 0.027 14.4 0.8 3.9 7.3 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase Ploopntkinase3 PF18751.1 KKF93253.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KKF93253.1 - 0.14 12.6 0.0 0.52 10.8 0.0 1.9 2 1 0 2 2 2 0 ABC transporter SET PF00856.28 KKF93254.1 - 5.3e-05 23.7 0.0 0.00025 21.5 0.0 2.1 2 1 0 2 2 2 1 SET domain AMPKBI PF04739.15 KKF93254.1 - 0.17 12.2 0.1 0.47 10.8 0.1 1.7 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain Fungal_trans PF04082.18 KKF93255.1 - 3.7e-33 114.7 0.5 5.7e-33 114.1 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF93255.1 - 1.1e-09 38.2 11.6 2.1e-09 37.4 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KKF93255.1 - 0.26 11.4 0.1 0.26 11.4 0.1 1.6 2 0 0 2 2 2 0 bZIP transcription factor GDPD PF03009.17 KKF93256.1 - 2.3e-25 89.8 0.0 4.4e-25 88.9 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Plus-3 PF03126.18 KKF93257.1 - 1.1e-19 70.9 0.0 2.4e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain COQ7 PF03232.13 KKF93258.1 - 7.7e-50 169.0 0.8 9.1e-50 168.8 0.8 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KKF93258.1 - 2.6e-05 24.6 0.0 3.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Rubrerythrin Coat_F PF07875.12 KKF93258.1 - 0.074 13.3 0.2 2.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Coat F domain PLDc PF00614.22 KKF93259.1 - 2.1e-18 65.6 0.5 3.9e-08 33.2 0.3 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KKF93259.1 - 8.2e-14 51.6 0.0 3.3e-08 33.5 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 KKF93259.1 - 8.2e-09 35.4 0.5 7.8e-08 32.3 0.0 2.8 3 1 0 3 3 3 1 PX domain Tubulin PF00091.25 KKF93260.1 - 9.2e-69 231.6 0.0 1.4e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKF93260.1 - 1.8e-34 118.6 0.7 3.1e-34 117.9 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KKF93260.1 - 1.2e-07 32.0 0.0 2.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KKF93260.1 - 0.013 15.2 0.0 0.056 13.1 0.0 2.0 2 0 0 2 2 2 0 Tubulin domain C2 PF00168.30 KKF93261.1 - 2e-17 63.3 0.0 3.3e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.13 KKF93261.1 - 0.99 9.3 13.6 1.3 8.9 13.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3573 PF12097.8 KKF93261.1 - 2.1 7.1 3.2 2.9 6.6 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Ndc1_Nup PF09531.10 KKF93261.1 - 2.6 6.6 6.9 3.5 6.2 6.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMEM234 PF10639.9 KKF93262.1 - 8.4e-28 96.7 0.4 1e-27 96.4 0.4 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 DUF1211 PF06736.11 KKF93262.1 - 0.0019 18.6 2.2 0.052 14.0 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1211) PetM PF08041.11 KKF93262.1 - 0.021 14.4 1.7 0.064 12.9 1.7 1.8 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 4HBT_2 PF13279.6 KKF93264.1 - 4.9e-07 30.3 0.0 6.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily adh_short PF00106.25 KKF93265.1 - 1.3e-36 125.9 0.5 1.4e-36 125.8 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF93265.1 - 4.4e-36 124.6 0.4 5e-36 124.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF93265.1 - 1.7e-09 37.8 0.2 1.9e-09 37.7 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKF93265.1 - 0.003 17.1 0.1 0.0034 16.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKF93265.1 - 0.045 13.1 0.0 0.073 12.5 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Arfaptin PF06456.13 KKF93265.1 - 0.13 11.8 0.2 0.17 11.4 0.2 1.1 1 0 0 1 1 1 0 Arfaptin-like domain ThiF PF00899.21 KKF93265.1 - 0.32 10.3 2.0 0.51 9.6 0.2 1.9 1 1 1 2 2 2 0 ThiF family PC4 PF02229.16 KKF93266.1 - 9e-24 82.9 0.2 2.1e-22 78.5 0.1 2.3 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) PXA PF02194.15 KKF93267.1 - 1.2e-32 113.4 2.1 4.2e-32 111.6 0.6 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KKF93267.1 - 3.3e-21 76.0 0.3 1.8e-20 73.6 0.0 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KKF93267.1 - 5.8e-08 32.7 0.0 1.6e-06 28.1 0.0 2.8 2 0 0 2 2 2 1 PX domain CN_hydrolase PF00795.22 KKF93268.1 - 3.8e-54 183.8 0.0 4.3e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Spermine_synth PF01564.17 KKF93269.1 - 2.3e-72 242.4 0.0 4e-72 241.6 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KKF93269.1 - 3e-20 71.8 0.0 5.2e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_31 PF13847.6 KKF93269.1 - 0.00021 21.1 0.0 0.00089 19.1 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF93269.1 - 0.00057 20.5 0.0 0.00098 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 KKF93269.1 - 0.0022 17.3 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 KKF93269.1 - 0.033 14.9 0.0 0.081 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 KKF93269.1 - 0.039 15.0 0.0 0.074 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain G-alpha PF00503.20 KKF93270.1 - 5.7e-109 364.5 0.0 7e-109 364.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KKF93270.1 - 1.2e-12 47.6 0.2 3e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKF93270.1 - 0.00057 19.3 0.4 0.083 12.2 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KKF93270.1 - 0.015 15.5 0.2 7.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KKF93270.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KKF93270.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GCS PF03074.16 KKF93271.1 - 4.8e-172 572.4 0.0 5.8e-172 572.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.27 KKF93272.1 - 7.3e-15 54.3 2.7 1.4e-14 53.4 2.7 1.5 1 0 0 1 1 1 1 GATA zinc finger Omptin PF01278.20 KKF93273.1 - 0.14 11.2 0.5 0.22 10.5 0.5 1.2 1 0 0 1 1 1 0 Omptin family UQ_con PF00179.26 KKF93274.1 - 5.8e-13 48.7 0.2 9.4e-12 44.8 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKF93274.1 - 0.034 14.4 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain DUF3248 PF11609.8 KKF93274.1 - 0.052 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Band_7 PF01145.25 KKF93275.1 - 4.8e-32 111.4 0.4 8.6e-32 110.6 0.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KKF93275.1 - 2e-22 79.0 0.6 5.1e-22 77.7 0.6 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 KKF93275.1 - 0.031 13.6 0.2 0.046 13.0 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 KKF93275.1 - 0.044 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family GSH-S_N PF02951.14 KKF93275.1 - 0.072 13.2 0.1 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain DCB PF16213.5 KKF93276.1 - 6.1e-38 130.2 8.6 2.4e-28 99.0 0.8 4.2 3 1 1 4 4 4 3 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KKF93276.1 - 1.9e-25 89.2 7.5 8.4e-21 73.8 2.8 3.3 3 0 0 3 3 3 3 C-terminal region of Mon2 protein Sec7_N PF12783.7 KKF93276.1 - 6e-14 52.2 0.3 6.8e-13 48.8 0.0 3.0 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KKF93276.1 - 1.9e-05 24.5 0.4 0.00055 19.7 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Radical_SAM_C PF16199.5 KKF93276.1 - 0.0043 17.0 0.0 3.5 7.7 0.0 2.9 2 0 0 2 2 2 2 Radical_SAM C-terminal domain DUF1539 PF07560.11 KKF93276.1 - 0.046 13.8 0.0 1e+02 3.0 0.0 4.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Xpo1 PF08389.12 KKF93276.1 - 1.8 8.6 5.1 1.5 8.8 0.2 3.1 3 0 0 3 3 3 0 Exportin 1-like protein zf-CCHC PF00098.23 KKF93277.1 - 3.2e-05 23.8 2.1 3.2e-05 23.8 2.1 1.7 2 0 0 2 2 2 1 Zinc knuckle Retrotran_gag_2 PF14223.6 KKF93277.1 - 0.00015 21.4 0.9 0.00015 21.4 0.9 2.4 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type SCAN PF02023.17 KKF93277.1 - 0.02 14.7 0.1 0.063 13.1 0.1 1.9 1 0 0 1 1 1 0 SCAN domain zf-CCHC_4 PF14392.6 KKF93277.1 - 0.087 12.6 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 KKF93277.1 - 0.33 10.9 5.1 0.68 9.9 5.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 KKF93277.1 - 1.3 8.8 4.6 2.8 7.7 4.6 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SAM_2 PF07647.17 KKF93278.1 - 1.7e-13 50.5 0.0 5.6e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 KKF93278.1 - 6.8e-11 41.6 0.1 2.1e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KKF93278.1 - 8.1e-11 41.6 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KKF93278.1 - 1.1e-08 35.5 0.0 3.9e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 KKF93278.1 - 1.6e-05 24.5 0.0 3.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KKF93278.1 - 0.0028 18.0 0.1 0.008 16.6 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.30 KKF93278.1 - 0.0053 17.2 0.0 0.014 15.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 KKF93278.1 - 0.081 13.2 0.0 0.61 10.4 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain NAD_binding_10 PF13460.6 KKF93279.1 - 6.8e-26 91.3 3.8 3.8e-25 88.9 3.8 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKF93279.1 - 0.00043 19.8 0.0 0.00098 18.6 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KKF93279.1 - 0.0092 15.2 0.0 0.014 14.5 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Chorismate_bind PF00425.18 KKF93279.1 - 0.012 15.2 0.1 1.7 8.1 0.0 2.1 2 0 0 2 2 2 0 chorismate binding enzyme NmrA PF05368.13 KKF93279.1 - 0.061 12.9 0.3 0.28 10.7 0.1 2.1 3 0 0 3 3 3 0 NmrA-like family OTU PF02338.19 KKF93280.1 - 3.3e-21 76.1 0.0 6.1e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KKF93280.1 - 0.00046 19.7 0.0 0.069 12.6 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain TPMT PF05724.11 KKF93281.1 - 4.3e-33 114.8 0.0 1.3e-29 103.4 0.0 2.0 1 1 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KKF93281.1 - 1.3e-10 41.4 0.0 1.9e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF93281.1 - 2.3e-08 34.6 0.0 5.5e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF93281.1 - 3.6e-08 34.0 0.0 7.2e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF93281.1 - 4.1e-07 30.7 0.0 3.3e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF93281.1 - 5.5e-07 29.5 0.0 3.2e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KKF93281.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Peptidase_MA_2 PF13485.6 KKF93281.1 - 0.083 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase MA superfamily Pkinase PF00069.25 KKF93282.1 - 1.3e-26 93.5 0.0 2e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF93282.1 - 2.5e-14 53.2 0.1 4.9e-14 52.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKF93282.1 - 2.4e-06 26.6 0.0 2.4e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Peptidase_M44 PF03410.13 KKF93282.1 - 0.016 13.8 0.0 0.024 13.2 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox TFIIA PF03153.13 KKF93282.1 - 6 6.8 21.8 9.4 6.1 21.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoporin_C PF03177.14 KKF93283.1 - 4.1e-143 478.3 14.6 5.4e-143 477.9 14.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KKF93283.1 - 8.8e-44 149.9 0.0 3.3e-21 75.5 0.0 2.3 1 1 1 2 2 2 2 Nup133 N terminal like AFG1_ATPase PF03969.16 KKF93284.1 - 8.8e-39 133.4 0.0 1.1e-19 70.6 0.0 4.1 4 0 0 4 4 4 4 AFG1-like ATPase Forkhead PF00250.18 KKF93285.1 - 3.2e-14 52.9 0.0 7e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KKF93285.1 - 0.0011 19.3 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain DUF3261 PF11659.8 KKF93287.1 - 0.11 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) Ank_4 PF13637.6 KKF93288.1 - 4.6e-10 39.8 1.3 0.014 16.0 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKF93288.1 - 2.3e-09 36.7 0.1 0.00098 19.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KKF93288.1 - 3.4e-09 37.2 0.0 0.0016 19.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKF93288.1 - 1.1e-08 35.2 0.5 0.00028 21.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KKF93288.1 - 1.1e-06 28.8 0.6 0.015 15.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 KKF93288.1 - 0.001 18.9 1.1 0.001 18.9 1.1 2.6 3 1 0 3 3 3 1 KilA-N domain FliD_C PF07195.12 KKF93288.1 - 0.11 12.0 5.5 0.36 10.2 1.4 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF148 PF02520.17 KKF93288.1 - 0.18 11.9 3.5 0.75 9.9 3.5 2.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 USP8_interact PF08941.10 KKF93288.1 - 0.44 10.3 2.6 0.87 9.4 2.1 1.7 1 1 0 1 1 1 0 USP8 interacting DUF3818 PF12825.7 KKF93288.1 - 1.4 7.9 4.5 2.2 7.2 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) LMBR1 PF04791.16 KKF93288.1 - 3.4 6.5 4.7 5.1 5.9 4.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ADIP PF11559.8 KKF93288.1 - 4.1 7.5 12.7 2.1 8.4 6.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rbsn PF11464.8 KKF93289.1 - 1.8e-18 66.0 0.2 2.6e-18 65.5 0.2 1.3 1 0 0 1 1 1 1 Rabenosyn Rab binding domain CP12 PF02672.15 KKF93289.1 - 0.028 15.1 0.1 0.037 14.8 0.1 1.3 1 0 0 1 1 1 0 CP12 domain Seryl_tRNA_N PF02403.22 KKF93289.1 - 0.045 14.0 0.1 0.048 13.9 0.1 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spectrin PF00435.21 KKF93289.1 - 0.055 14.0 0.1 0.11 13.0 0.1 1.5 1 1 1 2 2 2 0 Spectrin repeat DEAD PF00270.29 KKF93290.1 - 1.2e-24 87.1 0.5 2e-24 86.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF93290.1 - 1e-08 35.5 0.0 4.3e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF93290.1 - 9.5e-06 25.7 0.1 1.5e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KKF93290.1 - 0.00031 21.1 0.1 0.00066 20.0 0.1 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like Homeodomain PF00046.29 KKF93291.1 - 2.7e-15 55.9 0.6 5e-15 55.1 0.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KKF93291.1 - 0.0073 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain CBFD_NFYB_HMF PF00808.23 KKF93292.1 - 9.6e-10 38.6 0.1 2.2e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKF93292.1 - 0.0057 17.0 0.1 0.0057 17.0 0.1 2.6 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KKF93292.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold AMP-binding PF00501.28 KKF93293.1 - 2.1e-95 319.8 0.0 2.4e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKF93293.1 - 9.8e-10 39.3 0.0 2.6e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP11 PF06644.11 KKF93294.1 - 2.5e-95 319.4 0.0 3.4e-95 318.9 0.0 1.2 1 0 0 1 1 1 1 ATP11 protein SLD3 PF08639.10 KKF93295.1 - 5.4e-128 428.1 11.0 5.4e-128 428.1 11.0 2.6 2 1 0 2 2 2 2 DNA replication regulator SLD3 Trs65 PF12735.7 KKF93296.1 - 3.3e-93 312.6 0.0 6.5e-93 311.6 0.0 1.5 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Med16 PF11635.8 KKF93296.1 - 3.5e-71 240.2 3.7 5.1e-71 239.7 3.7 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 DEDD_Tnp_IS110 PF01548.17 KKF93296.1 - 0.0069 16.3 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 Transposase SNF2_N PF00176.23 KKF93297.1 - 4e-52 177.1 0.0 6.2e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KKF93297.1 - 7.8e-25 86.5 6.4 1e-18 67.0 1.4 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KKF93297.1 - 3.1e-20 72.6 0.0 9.6e-20 71.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 KKF93297.1 - 4.5e-15 55.8 0.0 4.5e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ResIII PF04851.15 KKF93297.1 - 1e-07 32.1 0.0 1.8e-06 28.1 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 KKF93297.1 - 8.7e-06 26.1 14.9 8.8e-05 22.8 0.5 4.7 2 1 1 3 3 3 2 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 KKF93297.1 - 0.0015 19.2 0.6 0.0015 19.2 0.6 3.2 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 SLIDE PF09111.10 KKF93297.1 - 0.0024 17.9 1.4 0.028 14.4 0.0 3.4 3 0 0 3 3 3 1 SLIDE ABC_tran PF00005.27 KKF93298.1 - 4.6e-33 114.6 0.0 1.2e-15 58.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKF93298.1 - 4.3e-13 49.2 0.1 1.4e-05 24.6 0.0 3.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 KKF93298.1 - 5.6e-13 48.5 5.0 5.6e-13 48.5 5.0 2.4 2 1 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 KKF93298.1 - 3e-11 43.7 4.0 0.11 12.3 1.2 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKF93298.1 - 1.9e-06 28.4 0.0 0.015 15.7 0.0 2.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KKF93298.1 - 2.2e-06 27.6 0.1 0.16 11.7 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KKF93298.1 - 3.6e-06 27.3 0.2 0.00071 19.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KKF93298.1 - 1.3e-05 25.7 0.0 0.011 16.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4 PF00037.27 KKF93298.1 - 3.2e-05 23.6 3.4 3.2e-05 23.6 3.4 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_23 PF13476.6 KKF93298.1 - 8.3e-05 23.2 0.0 0.026 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KKF93298.1 - 0.00014 21.8 0.0 0.53 10.2 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase Rad17 PF03215.15 KKF93298.1 - 0.00018 21.5 0.0 0.066 13.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 KKF93298.1 - 0.00038 20.1 0.1 0.47 10.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KKF93298.1 - 0.00042 20.7 0.4 0.16 12.4 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_18 PF13238.6 KKF93298.1 - 0.00045 20.8 0.0 1.5 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 KKF93298.1 - 0.00074 19.2 1.3 0.068 12.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KKF93298.1 - 0.001 18.9 0.0 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KKF93298.1 - 0.0015 17.3 0.3 0.003 16.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 KKF93298.1 - 0.0019 18.1 1.6 0.16 11.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 KKF93298.1 - 0.0019 17.9 0.1 2.1 8.0 0.0 2.9 3 0 0 3 3 3 1 Thymidylate kinase AAA_7 PF12775.7 KKF93298.1 - 0.004 16.7 0.7 0.053 13.0 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KKF93298.1 - 0.004 17.3 0.0 0.67 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 KKF93298.1 - 0.0044 17.1 10.7 0.01 16.0 10.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKF93298.1 - 0.0048 16.9 2.1 0.0048 16.9 2.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain TsaE PF02367.17 KKF93298.1 - 0.005 16.8 0.0 0.054 13.5 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KKF93298.1 - 0.0063 16.5 0.6 0.23 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KKF93298.1 - 0.01 15.0 0.0 0.75 8.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KKF93298.1 - 0.017 15.4 0.1 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_7 PF12838.7 KKF93298.1 - 0.018 15.6 1.1 0.018 15.6 1.1 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain AAA_14 PF13173.6 KKF93298.1 - 0.039 14.0 0.3 9.3 6.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KKF93298.1 - 0.04 13.6 0.2 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 KKF93298.1 - 0.05 13.8 10.1 0.11 12.7 10.1 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKF93298.1 - 0.056 14.4 0.2 0.056 14.4 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain MMR_HSR1 PF01926.23 KKF93298.1 - 0.1 12.7 0.4 16 5.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase VirE PF05272.11 KKF93298.1 - 0.11 12.2 0.0 7.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_17 PF13534.6 KKF93298.1 - 0.12 12.9 0.1 0.12 12.9 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKF93298.1 - 0.16 12.1 15.6 0.056 13.6 1.7 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 KKF93298.1 - 0.23 11.4 1.6 6.1 6.7 0.0 2.6 2 0 0 2 2 2 0 NTPase CLP1_P PF16575.5 KKF93298.1 - 0.25 11.1 0.7 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 KKF93298.1 - 0.31 10.8 2.9 0.33 10.7 0.0 2.5 3 1 1 4 4 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_8 PF13183.6 KKF93298.1 - 8.3 7.0 10.9 0.86 10.1 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKF93298.1 - 9.9 6.5 10.4 0.41 10.8 1.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.19 KKF93299.1 - 3e-44 149.0 18.7 3.8e-12 46.2 0.4 6.6 6 0 0 6 6 6 6 FF domain WW PF00397.26 KKF93299.1 - 7e-18 64.4 15.2 7.4e-10 38.8 1.6 2.7 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 KKF93299.1 - 3.5 7.9 11.4 4.5 7.6 0.4 3.3 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Acyl-CoA_dh_1 PF00441.24 KKF93301.1 - 2.9e-28 99.0 0.8 4.9e-28 98.2 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKF93301.1 - 1.4e-20 73.3 0.0 1e-19 70.5 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KKF93301.1 - 1.1e-13 51.8 0.1 2.4e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KKF93301.1 - 2.3e-13 50.6 1.1 4.7e-13 49.6 1.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Spo12 PF05032.12 KKF93302.1 - 1.7e-14 53.4 2.0 3.8e-14 52.3 2.0 1.7 1 0 0 1 1 1 1 Spo12 family MMR_HSR1_Xtn PF16897.5 KKF93303.1 - 5.3e-36 122.9 2.9 1.6e-35 121.3 0.8 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KKF93303.1 - 1.1e-20 73.9 0.2 2.6e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KKF93303.1 - 1.5e-18 66.6 0.0 2.5e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KKF93303.1 - 1.9e-12 47.0 0.0 3.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKF93303.1 - 0.0022 18.1 3.7 0.053 13.6 0.0 2.6 2 1 1 3 3 3 2 Dynamin family Baculo_ME53 PF06061.11 KKF93303.1 - 0.073 12.3 4.1 0.085 12.1 2.2 2.0 2 1 0 2 2 2 0 Baculoviridae ME53 MeaB PF03308.16 KKF93303.1 - 0.082 11.9 0.1 0.18 10.8 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Torus PF16131.5 KKF93304.1 - 5.2e-44 149.4 0.4 1.1e-43 148.3 0.0 1.7 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KKF93304.1 - 8.1e-08 32.0 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KKF93304.1 - 6.6e-05 22.8 0.5 6.6e-05 22.8 0.5 1.9 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 KKF93304.1 - 0.0066 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 KKF93304.1 - 0.048 13.6 0.5 0.093 12.7 0.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cut12 PF11500.8 KKF93305.1 - 2e-30 105.6 14.6 2e-30 105.6 14.6 3.6 2 1 1 3 3 3 1 Spindle pole body formation-associated protein UreF PF01730.16 KKF93305.1 - 2.9e-19 70.0 0.4 2.9e-19 70.0 0.4 2.7 3 0 0 3 3 2 1 UreF Pox_A_type_inc PF04508.12 KKF93305.1 - 0.047 13.6 18.2 0.58 10.1 0.4 4.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat NPV_P10 PF05531.12 KKF93305.1 - 0.29 11.6 10.3 4.2 7.9 0.6 3.9 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3847 PF12958.7 KKF93305.1 - 0.73 10.0 11.2 0.67 10.1 1.7 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3847) Rootletin PF15035.6 KKF93305.1 - 0.85 9.6 37.5 0.25 11.4 23.8 2.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 KKF93305.1 - 1.5 8.9 37.7 3 7.9 19.7 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 KKF93305.1 - 2.2 7.1 41.8 0.92 8.3 4.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 KKF93305.1 - 2.7 8.4 9.3 7.3 7.1 0.7 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Csm1_N PF18504.1 KKF93305.1 - 3.2 8.2 25.9 0.14 12.5 0.5 4.7 4 1 1 5 5 5 0 Csm1 N-terminal domain MerR-DNA-bind PF09278.11 KKF93305.1 - 4 8.0 18.3 1 9.9 1.9 4.1 3 1 0 3 3 3 0 MerR, DNA binding DUF2570 PF10828.8 KKF93305.1 - 4.3 7.2 11.2 5.8 6.8 0.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) Cauli_AT PF03233.13 KKF93305.1 - 4.9 7.1 16.4 0.81 9.6 2.3 3.4 1 1 1 3 3 3 0 Aphid transmission protein DUF16 PF01519.16 KKF93305.1 - 7.6 7.1 18.2 1.6 9.3 0.8 3.5 1 1 1 3 3 3 0 Protein of unknown function DUF16 Atg14 PF10186.9 KKF93305.1 - 8.5 5.4 36.7 0.72 8.9 18.0 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 KKF93306.1 - 1.4e-72 244.3 0.0 6.7e-34 117.4 0.0 3.8 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 KKF93306.1 - 2.3e-69 233.8 0.4 2.3e-69 233.8 0.4 3.1 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 KKF93306.1 - 3.7e-47 160.8 0.0 4.5e-19 68.7 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 KKF93306.1 - 2.8e-13 49.8 0.0 2.8e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 KKF93306.1 - 5.4e-09 36.3 0.0 2.2e-08 34.4 0.0 2.2 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KKF93306.1 - 1.3e-05 25.3 8.3 0.012 15.5 0.0 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KKF93306.1 - 7.8e-05 22.1 0.0 0.023 14.0 0.0 2.9 3 1 0 3 3 3 1 Kinase-like Kdo PF06293.14 KKF93306.1 - 0.00064 19.1 0.3 0.51 9.7 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KKF93306.1 - 0.001 18.0 16.0 0.014 14.2 0.1 2.8 2 1 0 2 2 2 2 Fungal protein kinase HEAT_2 PF13646.6 KKF93306.1 - 0.0024 18.3 0.0 0.011 16.2 0.0 2.1 1 0 0 1 1 1 1 HEAT repeats BSP_II PF05432.11 KKF93306.1 - 0.0048 16.7 10.7 0.0048 16.7 10.7 2.0 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) FTA2 PF13095.6 KKF93306.1 - 0.009 15.7 3.4 2.2 7.9 0.0 3.8 4 0 0 4 4 4 1 Kinetochore Sim4 complex subunit FTA2 PMSR PF01625.21 KKF93307.1 - 7.9e-61 204.7 0.1 9.3e-61 204.5 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Bax1-I PF01027.20 KKF93308.1 - 4.9e-34 118.0 9.4 7e-34 117.5 9.4 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CGI-121 PF08617.10 KKF93309.1 - 1.3e-49 168.5 0.4 2.2e-49 167.7 0.4 1.4 1 0 0 1 1 1 1 Kinase binding protein CGI-121 cNMP_binding PF00027.29 KKF93309.1 - 1.1e-06 28.6 0.0 2.7e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 KKF93309.1 - 2.9e-06 27.8 2.7 5e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein LRR_4 PF12799.7 KKF93309.1 - 0.00013 22.3 0.0 0.015 15.7 0.0 3.1 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKF93309.1 - 0.0027 18.0 4.0 6.4 7.7 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 KKF93309.1 - 0.0078 16.2 1.7 0.49 10.6 0.1 4.1 4 0 0 4 4 4 1 Leucine Rich repeat Pro_dh PF01619.18 KKF93310.1 - 4.8e-70 236.4 0.0 5.9e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Aldo_ket_red PF00248.21 KKF93311.1 - 1.7e-57 194.9 0.0 1.9e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 4HBT PF03061.22 KKF93312.1 - 1.7e-07 31.5 0.0 2.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 2-Hacid_dh_C PF02826.19 KKF93313.1 - 1.4e-47 161.4 0.0 7.6e-47 159.0 0.0 2.2 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KKF93313.1 - 7.1e-13 48.2 2.6 1.3e-12 47.4 2.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2-Hacid_dh PF00389.30 KKF93313.1 - 0.0099 15.5 0.0 0.034 13.8 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKF93313.1 - 0.038 14.2 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase eIF3m_C_helix PF18005.1 KKF93313.1 - 0.039 13.6 0.2 0.11 12.2 0.2 1.9 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Kinesin PF00225.23 KKF93314.1 - 5.9e-116 387.0 0.1 8.6e-116 386.5 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKF93314.1 - 3.1e-27 95.3 0.0 7.4e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 KKF93314.1 - 1.1 9.5 15.3 1.7 8.9 6.7 2.7 1 1 1 2 2 2 0 Herpesvirus UL14-like protein DUF3417 PF11897.8 KKF93314.1 - 2 8.9 5.1 1.2 9.6 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) NIF PF03031.18 KKF93315.1 - 6.6e-37 126.7 0.0 1e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EMC3_TMCO1 PF01956.16 KKF93315.1 - 3.4 7.4 5.1 6 6.6 5.1 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RNase_PH PF01138.21 KKF93316.1 - 1.5e-35 122.6 0.3 2.1e-35 122.1 0.3 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKF93316.1 - 0.098 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF4242 PF14026.6 KKF93316.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Thioredoxin PF00085.20 KKF93317.1 - 1.5e-30 105.2 0.0 1.3e-24 86.2 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KKF93317.1 - 2.8e-06 27.7 0.1 0.02 15.3 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KKF93317.1 - 3.9e-06 27.1 0.0 0.97 9.8 0.0 4.2 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_6 PF13848.6 KKF93317.1 - 6.2e-06 26.2 0.0 0.0061 16.5 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KKF93317.1 - 2.9e-05 23.6 0.0 0.0028 17.0 0.0 2.8 2 1 1 3 3 3 1 OST3 / OST6 family, transporter family TraF PF13728.6 KKF93317.1 - 4.5e-05 23.4 4.2 0.0058 16.5 0.0 3.1 3 0 0 3 3 3 1 F plasmid transfer operon protein QSOX_Trx1 PF18108.1 KKF93317.1 - 0.0086 16.2 0.0 0.051 13.8 0.0 2.1 2 0 0 2 2 2 1 QSOX Trx-like domain AhpC-TSA PF00578.21 KKF93317.1 - 0.014 15.3 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 KKF93317.1 - 0.075 13.2 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 KKF93317.1 - 0.14 12.2 0.1 6.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain Vta1 PF04652.16 KKF93318.1 - 1.3e-48 164.7 5.5 4.9e-48 162.8 3.1 2.0 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KKF93318.1 - 2.9e-17 62.1 0.7 5.4e-17 61.2 0.7 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain ADH_N_assoc PF13823.6 KKF93318.1 - 0.5 10.3 1.8 1 9.3 1.8 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated DUF295 PF03478.18 KKF93323.1 - 0.099 12.2 0.1 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF295) Patatin PF01734.22 KKF93326.1 - 1.9e-05 25.0 0.2 5.7e-05 23.4 0.2 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase AAA_16 PF13191.6 KKF93326.1 - 0.035 14.5 0.1 0.084 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KKF93326.1 - 0.053 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KKF93326.1 - 0.13 12.7 0.7 24 5.3 0.3 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sas10_Utp3 PF04000.15 KKF93327.1 - 7.2e-12 45.8 0.3 1.1e-11 45.1 0.3 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family FmiP_Thoc5 PF09766.9 KKF93327.1 - 0.026 13.8 1.8 2.6 7.2 0.4 2.0 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 CIA30 PF08547.12 KKF93328.1 - 2.6e-41 141.3 0.1 3.2e-41 141.0 0.1 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SSF PF00474.17 KKF93329.1 - 3.7e-10 39.2 34.7 4.9e-09 35.5 34.7 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family MazG-like PF12643.7 KKF93329.1 - 0.12 12.7 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 MazG-like family Tim44 PF04280.15 KKF93330.1 - 1.2e-07 32.0 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 KKF93330.1 - 7.9e-06 25.1 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein EOS1 PF12326.8 KKF93331.1 - 7.3e-15 55.3 2.1 7.3e-15 55.3 2.1 1.8 2 0 0 2 2 2 1 N-glycosylation protein ATP-synt_I PF03899.15 KKF93331.1 - 0.88 10.0 4.1 15 6.1 0.2 2.4 2 0 0 2 2 2 0 ATP synthase I chain SUI1 PF01253.22 KKF93332.1 - 7.4e-27 93.7 1.2 9.2e-27 93.4 1.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 AdoMet_MTase PF07757.13 KKF93333.1 - 2.4e-16 60.1 0.0 4.9e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Epiglycanin_C PF14654.6 KKF93333.1 - 0.08 13.0 0.5 0.8 9.8 0.2 2.2 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Serglycin PF04360.12 KKF93333.1 - 0.15 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Serglycin Dioxygenase_C PF00775.21 KKF93334.1 - 6.1e-46 156.1 0.0 9e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KKF93334.1 - 1.9e-30 104.5 0.0 3.3e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KKF93334.1 - 0.0025 18.0 1.7 0.004 17.4 0.0 2.2 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 KKF93334.1 - 0.017 15.4 0.1 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Prealbumin-like fold domain MRI PF15325.6 KKF93334.1 - 0.54 11.4 3.2 1.1 10.3 3.2 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection TFIIS_C PF01096.18 KKF93335.1 - 2.3e-17 62.5 3.2 2.3e-17 62.5 3.2 2.8 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KKF93335.1 - 5.3e-07 29.4 2.2 4.9e-06 26.3 0.3 2.6 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KKF93335.1 - 0.014 15.3 1.0 0.014 15.3 1.0 2.8 3 1 0 3 3 3 0 Transposase zinc-ribbon domain UPF0547 PF10571.9 KKF93335.1 - 0.19 11.8 0.4 0.19 11.8 0.4 3.7 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.6 KKF93335.1 - 0.3 11.0 6.0 0.22 11.5 1.7 2.8 2 1 0 2 2 2 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.11 KKF93335.1 - 0.46 10.5 6.7 0.37 10.8 1.1 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Med31 PF05669.12 KKF93336.1 - 3.8e-36 123.0 1.3 4.2e-36 122.8 1.3 1.0 1 0 0 1 1 1 1 SOH1 RloB PF13707.6 KKF93338.1 - 0.029 14.6 0.2 0.053 13.7 0.2 1.4 1 0 0 1 1 1 0 RloB-like protein Oxysterol_BP PF01237.18 KKF93339.1 - 4e-109 364.9 0.0 8.9e-109 363.7 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KKF93339.1 - 1.4e-37 127.9 1.5 1.5e-37 127.7 0.1 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KKF93339.1 - 1.1e-07 32.3 0.4 8.5e-07 29.5 0.0 2.6 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 KKF93339.1 - 0.15 12.5 0.6 11 6.5 0.6 3.0 1 1 0 1 1 1 0 Pleckstrin homology domain NMT_C PF02799.15 KKF93340.1 - 5.8e-79 264.5 0.0 1e-78 263.7 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KKF93340.1 - 1e-67 227.0 0.0 9.9e-67 223.8 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KKF93340.1 - 1e-05 25.6 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKF93340.1 - 0.0039 17.4 0.0 0.0084 16.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CDC45 PF02724.14 KKF93340.1 - 0.29 9.4 3.3 0.4 8.9 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.8 KKF93340.1 - 0.76 9.6 7.2 1.4 8.7 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Sporozoite_P67 PF05642.11 KKF93340.1 - 2.1 6.3 7.1 2.8 5.9 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CCDC106 PF15794.5 KKF93340.1 - 5 6.8 8.5 8.2 6.1 8.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 NIBRIN_BRCT_II PF16508.5 KKF93341.1 - 1.1e-34 119.3 0.0 4.8e-34 117.2 0.0 2.1 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein EF-hand_1 PF00036.32 KKF93341.1 - 2.7e-09 35.9 15.7 3.5e-05 23.0 0.5 4.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KKF93341.1 - 1.4e-08 35.1 9.5 0.0001 22.7 0.5 4.7 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_8 PF13833.6 KKF93341.1 - 1.1e-06 28.4 1.7 0.031 14.1 0.2 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KKF93341.1 - 1.2e-06 27.9 17.7 6.3e-05 22.6 1.3 4.9 5 0 0 5 5 5 2 EF-hand domain EF-hand_5 PF13202.6 KKF93341.1 - 1.1e-05 24.6 7.9 0.014 14.9 0.0 3.8 4 0 0 4 4 4 2 EF hand RTT107_BRCT_5 PF16770.5 KKF93341.1 - 0.002 18.0 0.0 0.0066 16.3 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain EF-hand_4 PF12763.7 KKF93341.1 - 0.024 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF4602 PF15375.6 KKF93341.1 - 0.69 10.2 4.8 6.8 7.0 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) Macoilin PF09726.9 KKF93341.1 - 8.4 4.8 6.4 14 4.0 6.4 1.3 1 0 0 1 1 1 0 Macoilin family SlyX PF04102.12 KKF93342.1 - 0.069 13.8 1.8 0.24 12.0 1.8 2.0 1 0 0 1 1 1 0 SlyX DnaJ-X PF14308.6 KKF93343.1 - 1.8e-76 256.2 6.0 1.8e-76 256.2 6.0 2.2 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KKF93343.1 - 9.6e-26 89.7 0.3 9.6e-26 89.7 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain TP2 PF01254.18 KKF93343.1 - 0.045 14.4 3.6 0.096 13.3 3.6 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 SQS_PSY PF00494.19 KKF93344.1 - 1.2e-32 113.5 0.0 2.9e-32 112.2 0.0 1.6 2 0 0 2 2 2 1 Squalene/phytoene synthase Peptidase_S8 PF00082.22 KKF93345.1 - 7.9e-32 110.7 13.2 1.7e-31 109.6 13.2 1.5 1 0 0 1 1 1 1 Subtilase family CDCA PF18484.1 KKF93345.1 - 0.21 11.4 1.6 0.36 10.7 0.1 2.1 2 1 1 3 3 3 0 Cadmium carbonic anhydrase repeat FAD_binding_4 PF01565.23 KKF93346.1 - 2.7e-13 49.9 0.1 4.9e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Mannosyl_trans PF05007.13 KKF93347.1 - 5.7e-32 111.6 6.5 8.1e-32 111.1 6.5 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) DUF1045 PF06299.12 KKF93347.1 - 0.051 13.6 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) Translin PF01997.16 KKF93348.1 - 1.5e-58 198.2 0.0 1.7e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.23 KKF93348.1 - 0.037 14.6 0.1 0.43 11.2 0.0 2.4 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Fungal_trans PF04082.18 KKF93349.1 - 2.6e-18 66.0 0.1 9.2e-18 64.2 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Mpv17_PMP22 PF04117.12 KKF93350.1 - 6.5e-15 55.1 1.3 6.5e-15 55.1 1.3 2.0 3 0 0 3 3 3 1 Mpv17 / PMP22 family UPF0492 PF15744.5 KKF93350.1 - 5.6 6.1 13.4 8 5.6 13.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Spt20 PF12090.8 KKF93350.1 - 9.1 5.8 14.7 15 5.1 14.7 1.3 1 0 0 1 1 1 0 Spt20 family Diphthamide_syn PF01866.17 KKF93351.1 - 5.3e-83 278.9 0.0 6.4e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MARVEL PF01284.23 KKF93352.1 - 0.00014 21.9 18.0 0.0002 21.4 18.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain zf-U1 PF06220.12 KKF93355.1 - 4.8e-22 77.4 3.5 7.5e-22 76.8 3.5 1.3 1 0 0 1 1 1 1 U1 zinc finger Acetyltransf_1 PF00583.25 KKF93356.1 - 0.0086 16.3 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TMEM40 PF15817.5 KKF93356.1 - 0.27 11.0 2.1 0.52 10.1 2.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 40 family SOG2 PF10428.9 KKF93357.1 - 6.8 5.8 17.8 9.1 5.3 17.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SUR7 PF06687.12 KKF93358.1 - 7.9e-33 113.9 15.4 1.1e-32 113.5 15.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family Amidohydro_2 PF04909.14 KKF93359.1 - 3.8e-18 66.3 0.1 1.2e-17 64.7 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase AMPK1_CBM PF16561.5 KKF93360.1 - 5.3e-05 23.4 0.0 9.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Sec3_C PF09763.9 KKF93360.1 - 0.29 9.4 3.5 0.33 9.3 3.5 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 HD PF01966.22 KKF93361.1 - 2.6e-09 37.3 0.2 5.2e-09 36.4 0.2 1.5 2 0 0 2 2 2 1 HD domain Transp_cyt_pur PF02133.15 KKF93363.1 - 1.3e-153 512.0 33.6 1.5e-153 511.7 33.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sld5 PF05916.11 KKF93363.1 - 4e-26 91.6 0.0 6.3e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Sas10_Utp3 PF04000.15 KKF93364.1 - 1.3e-14 54.6 0.3 4.2e-14 52.9 0.3 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family EMP70 PF02990.16 KKF93365.1 - 8.1e-203 674.8 13.5 9.9e-203 674.5 13.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Med4 PF10018.9 KKF93366.1 - 1.3e-35 122.8 7.5 1.8e-35 122.4 6.9 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 NEMP PF10225.9 KKF93366.1 - 1.7 8.3 2.7 3.3 7.3 2.7 1.4 1 0 0 1 1 1 0 NEMP family Rrn6 PF10214.9 KKF93366.1 - 9.5 4.6 16.5 0.76 8.2 4.2 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor QCR10 PF09796.9 KKF93367.1 - 9.5e-29 99.3 0.4 1.2e-28 98.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DIE2_ALG10 PF04922.12 KKF93368.1 - 2e-117 392.8 0.7 4.5e-117 391.7 0.7 1.6 1 1 0 1 1 1 1 DIE2/ALG10 family AMP-binding PF00501.28 KKF93368.1 - 3.4e-57 193.9 0.0 4.8e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKF93368.1 - 2.4e-13 50.9 0.1 4.5e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SPX PF03105.19 KKF93369.1 - 0.47 10.3 10.4 0.59 10.0 10.4 1.1 1 0 0 1 1 1 0 SPX domain MAP65_ASE1 PF03999.12 KKF93369.1 - 2.6 6.6 12.1 3.8 6.1 12.1 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Macoilin PF09726.9 KKF93369.1 - 7.7 4.9 8.6 8.3 4.8 8.6 1.1 1 0 0 1 1 1 0 Macoilin family U-box PF04564.15 KKF93370.1 - 2.7e-20 72.3 0.0 6.9e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 KKF93370.1 - 8.7e-14 50.5 1.0 0.0026 17.7 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKF93370.1 - 1.4e-13 50.0 2.9 0.00028 20.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKF93370.1 - 1.7e-06 28.2 1.0 0.0026 18.0 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKF93370.1 - 9.5e-06 25.7 1.9 0.11 13.0 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKF93370.1 - 3e-05 24.5 0.6 0.0057 17.1 0.6 2.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKF93370.1 - 5e-05 22.9 1.2 0.00058 19.5 0.1 2.7 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 KKF93370.1 - 5.1e-05 23.8 0.0 2.1 9.4 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKF93370.1 - 0.00012 22.0 1.8 0.76 10.1 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKF93370.1 - 0.00056 20.5 0.0 0.018 15.7 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 KKF93370.1 - 0.0027 17.8 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein CHIP_TPR_N PF18391.1 KKF93370.1 - 0.0028 18.4 11.0 0.0079 16.9 11.0 1.8 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain ANAPC3 PF12895.7 KKF93370.1 - 0.0048 17.1 1.8 0.03 14.6 0.9 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KKF93370.1 - 0.0094 15.9 0.2 1.8 8.7 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat HemY_N PF07219.13 KKF93370.1 - 0.15 12.3 0.4 16 5.8 0.9 2.3 2 0 0 2 2 2 0 HemY protein N-terminus Mg_trans_NIPA PF05653.14 KKF93371.1 - 1.4e-91 306.7 26.8 1.8e-91 306.3 26.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KKF93371.1 - 1.3e-05 25.4 7.6 1.3e-05 25.4 7.6 3.7 3 1 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 KKF93371.1 - 0.0021 17.6 6.5 0.0021 17.6 6.5 2.3 1 1 0 2 2 2 1 Solute carrier family 35 IBR PF01485.21 KKF93372.1 - 3.3e-20 72.1 41.4 2.9e-11 43.4 5.3 4.8 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KKF93372.1 - 0.033 14.1 0.1 0.033 14.1 0.1 4.9 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.6 KKF93372.1 - 0.087 12.8 0.3 0.087 12.8 0.3 4.2 4 0 0 4 4 4 0 zinc-ribbon domain DUF2333 PF10095.9 KKF93372.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) zf-UDP PF14569.6 KKF93372.1 - 2 8.6 11.0 5 7.3 0.0 3.4 2 1 1 3 3 3 0 Zinc-binding RING-finger SKG6 PF08693.10 KKF93373.1 - 0.096 12.1 0.1 0.27 10.7 0.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PROCN PF08083.11 KKF93374.1 - 5.4e-230 763.1 8.3 8.8e-230 762.4 8.3 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KKF93374.1 - 5.4e-126 418.8 0.9 9.3e-126 418.1 0.9 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KKF93374.1 - 1.7e-88 294.6 2.5 3.7e-88 293.5 1.7 2.1 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KKF93374.1 - 8.1e-79 262.9 4.0 2.4e-78 261.3 4.0 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KKF93374.1 - 6e-71 236.8 0.1 1.3e-70 235.7 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KKF93374.1 - 2.4e-44 149.6 0.2 7.7e-44 148.0 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KKF93374.1 - 3.1e-42 143.4 0.0 9.6e-42 141.8 0.0 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain Urb2 PF10441.9 KKF93375.1 - 1.4e-54 185.1 0.0 2.9e-54 184.1 0.0 1.5 1 0 0 1 1 1 1 Urb2/Npa2 family RNA_pol_I_A49 PF06870.12 KKF93376.1 - 2.4e-82 276.9 0.4 2.9e-82 276.6 0.4 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Vps51 PF08700.11 KKF93377.1 - 2.4e-13 50.0 0.9 9e-13 48.1 0.9 2.1 1 0 0 1 1 1 1 Vps51/Vps67 CRR7 PF12095.8 KKF93377.1 - 0.077 13.4 3.8 2.4 8.7 0.2 3.7 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 RNase_J_C PF17770.1 KKF93377.1 - 0.22 12.6 1.0 3.1 8.9 0.1 3.2 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain Trypan_PARP PF05887.11 KKF93377.1 - 0.23 11.4 21.2 0.14 12.1 18.9 1.7 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 KKF93377.1 - 0.39 9.2 1.7 0.59 8.6 1.7 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Jacalin PF01419.17 KKF93378.1 - 8.4e-06 25.7 0.6 0.00018 21.5 0.0 2.4 2 0 0 2 2 2 1 Jacalin-like lectin domain SH3_1 PF00018.28 KKF93379.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 SH3 domain DUF1027 PF06265.11 KKF93379.1 - 0.16 12.0 0.1 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) ELFV_dehydrog PF00208.21 KKF93380.1 - 7.3e-62 209.3 0.0 1.2e-61 208.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KKF93380.1 - 1.4e-19 69.2 0.0 2.1e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KKF93380.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain His_Phos_1 PF00300.22 KKF93381.1 - 0.0015 18.3 0.0 0.0018 18.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rax2 PF12768.7 KKF93382.1 - 2.7e-65 219.8 2.2 4.1e-64 216.0 0.0 3.9 3 1 1 4 4 4 2 Cortical protein marker for cell polarity Kelch_6 PF13964.6 KKF93382.1 - 0.00064 19.9 2.9 4.4 7.7 0.0 5.2 4 1 1 5 5 5 3 Kelch motif SF3b1 PF08920.10 KKF93384.1 - 1.5e-16 61.0 9.5 1.5e-16 61.0 9.5 2.8 2 1 1 3 3 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KKF93384.1 - 1.2e-12 48.1 4.6 0.055 13.9 0.1 8.0 5 2 3 9 9 9 4 HEAT repeats HEAT_EZ PF13513.6 KKF93384.1 - 7.5e-12 45.5 3.7 0.0085 16.6 0.0 6.8 6 1 1 7 7 7 3 HEAT-like repeat HEAT PF02985.22 KKF93384.1 - 1.2e-09 37.6 6.6 0.59 10.5 0.0 9.1 9 0 0 9 9 9 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KKF93384.1 - 0.00042 20.9 0.2 6.8 7.4 0.0 5.0 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 KKF93384.1 - 0.0037 17.0 0.3 0.93 9.1 0.0 3.9 5 0 0 5 5 5 1 NUC173 domain UNC45-central PF11701.8 KKF93384.1 - 0.0041 17.1 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KKF93384.1 - 0.036 13.6 0.0 1.6 8.3 0.0 3.0 3 0 0 3 3 3 0 CLASP N terminal Arm PF00514.23 KKF93384.1 - 0.081 13.0 0.4 51 4.1 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 KKF93384.1 - 0.095 12.6 5.1 1.4 8.8 0.0 4.9 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) MMS19_C PF12460.8 KKF93384.1 - 0.16 11.1 0.0 2.8 7.0 0.0 2.9 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal RRM_1 PF00076.22 KKF93385.1 - 1.1e-30 105.2 0.0 5.7e-15 54.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKF93385.1 - 2.1e-06 27.5 0.0 0.038 13.8 0.0 3.5 3 1 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KKF93385.1 - 0.15 12.1 0.0 2.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KKF93385.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.11 KKF93385.1 - 8.5 7.1 21.8 19 6.0 21.8 1.6 1 0 0 1 1 1 0 Glycine rich protein family Ribosomal_S13_N PF08069.12 KKF93386.1 - 1.4e-28 98.7 0.1 2.6e-28 97.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KKF93386.1 - 1.5e-14 54.0 0.7 2.5e-14 53.3 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KKF93386.1 - 0.079 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain VRR_NUC PF08774.11 KKF93387.1 - 9.3e-24 83.6 0.0 6e-23 81.0 0.0 2.0 2 0 0 2 2 2 1 VRR-NUC domain CBFB_NFYA PF02045.15 KKF93389.1 - 2.6e-28 98.4 5.7 5.5e-28 97.4 5.7 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 KKF93389.1 - 0.011 14.9 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 Hus1-like protein APH PF01636.23 KKF93390.1 - 2.7e-41 142.1 0.0 4.7e-26 92.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 KKF93390.1 - 5.3e-10 39.1 0.0 3.2e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 KKF93390.1 - 0.016 14.1 0.0 0.056 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KKF93390.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KKF93390.1 - 0.062 12.5 0.0 5.9 6.0 0.0 2.3 1 1 1 2 2 2 0 Fructosamine kinase Kinase-like PF14531.6 KKF93390.1 - 0.11 11.8 0.1 13 5.0 0.0 2.5 1 1 1 2 2 2 0 Kinase-like AAA_2 PF07724.14 KKF93392.1 - 7.6e-44 149.8 0.0 3.6e-43 147.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KKF93392.1 - 1.4e-34 118.1 1.9 1.4e-34 118.1 1.9 2.5 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KKF93392.1 - 1e-25 89.6 0.2 2.6e-25 88.3 0.2 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KKF93392.1 - 2.9e-20 73.0 0.0 3.2e-11 43.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKF93392.1 - 4.3e-12 46.2 0.0 3.7e-08 33.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKF93392.1 - 6.1e-09 36.5 2.2 0.0022 18.4 0.1 4.1 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KKF93392.1 - 3.3e-07 30.7 4.0 0.0077 16.5 0.1 3.9 3 2 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KKF93392.1 - 3.2e-06 26.9 0.2 0.00066 19.4 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 KKF93392.1 - 2.4e-05 23.8 0.0 0.0062 16.0 0.0 3.4 3 1 0 3 3 2 1 Bacterial TniB protein ATPase_2 PF01637.18 KKF93392.1 - 2.7e-05 24.2 5.1 0.49 10.3 0.0 4.2 3 2 1 4 4 3 2 ATPase domain predominantly from Archaea NACHT PF05729.12 KKF93392.1 - 4.7e-05 23.4 0.1 0.31 11.0 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 KKF93392.1 - 0.00013 22.0 0.0 0.6 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KKF93392.1 - 0.00015 21.4 0.0 0.6 9.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 KKF93392.1 - 0.00047 20.7 1.4 0.18 12.3 0.0 3.5 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 KKF93392.1 - 0.00065 20.3 1.1 0.25 11.9 0.0 3.3 3 1 1 4 4 2 1 AAA domain IstB_IS21 PF01695.17 KKF93392.1 - 0.001 18.8 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ResIII PF04851.15 KKF93392.1 - 0.002 18.2 0.1 2.5 8.1 0.0 3.5 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 KKF93392.1 - 0.0032 17.2 0.2 1.1 9.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KKF93392.1 - 0.0034 17.6 0.3 8 6.7 0.0 3.7 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KKF93392.1 - 0.004 16.6 0.1 2 7.7 0.0 2.9 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KKF93392.1 - 0.004 17.5 0.1 1 9.8 0.0 2.9 2 1 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KKF93392.1 - 0.0041 16.7 0.1 0.08 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KKF93392.1 - 0.0043 17.0 0.3 1.5 8.7 0.0 2.9 2 1 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KKF93392.1 - 0.0096 15.7 0.2 0.45 10.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 KKF93392.1 - 0.0099 15.1 0.3 0.62 9.2 0.2 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF815) SRP54 PF00448.22 KKF93392.1 - 0.01 15.5 0.1 0.58 9.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 KKF93392.1 - 0.016 15.4 0.1 3.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase OEP PF02321.18 KKF93392.1 - 0.017 14.9 4.0 0.035 13.9 4.0 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein TsaE PF02367.17 KKF93392.1 - 0.018 15.0 0.1 7.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KKF93392.1 - 0.018 15.4 0.9 0.52 10.6 0.1 3.1 3 1 0 3 3 2 0 AAA domain Rootletin PF15035.6 KKF93392.1 - 0.032 14.3 5.7 0.057 13.4 5.7 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PhoH PF02562.16 KKF93392.1 - 0.036 13.5 1.4 0.64 9.4 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein Zeta_toxin PF06414.12 KKF93392.1 - 0.038 13.3 0.0 1.6 7.9 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 KKF93392.1 - 0.043 13.6 0.0 0.79 9.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UvrD-helicase PF00580.21 KKF93392.1 - 0.061 12.8 2.6 0.22 11.0 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_33 PF13671.6 KKF93392.1 - 0.09 12.9 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KKF93392.1 - 0.13 11.4 0.0 2.8 7.0 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase DUF4349 PF14257.6 KKF93392.1 - 0.15 11.5 7.5 0.59 9.5 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) AAA_21 PF13304.6 KKF93392.1 - 0.5 10.1 4.8 1.5 8.5 0.0 3.6 5 1 1 6 6 5 0 AAA domain, putative AbiEii toxin, Type IV TA system RF-1 PF00472.20 KKF93392.1 - 0.6 10.0 3.2 1.2 9.0 3.2 1.5 1 0 0 1 1 1 0 RF-1 domain AAA_23 PF13476.6 KKF93392.1 - 1.9 9.0 14.4 78 3.7 12.5 3.1 2 1 0 2 2 2 0 AAA domain Seryl_tRNA_N PF02403.22 KKF93392.1 - 2.6 8.3 11.8 3 8.1 9.3 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_L6e PF01159.19 KKF93393.1 - 1.5e-39 135.0 0.3 2e-39 134.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L6e Peptidase_M49 PF03571.15 KKF93394.1 - 3.1e-244 811.5 0.0 3.7e-244 811.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 FA_desaturase PF00487.24 KKF93395.1 - 3.1e-10 40.3 32.2 3.1e-10 40.3 32.2 2.0 1 1 1 2 2 2 1 Fatty acid desaturase SRP-alpha_N PF04086.13 KKF93396.1 - 1.3e-65 222.3 8.4 5.1e-63 213.7 8.4 2.3 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KKF93396.1 - 3.6e-52 176.9 0.1 7.1e-52 175.9 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KKF93396.1 - 2.7e-09 37.1 0.3 6.5e-09 35.9 0.3 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KKF93396.1 - 4.2e-06 25.9 0.0 9.5e-06 24.8 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 KKF93396.1 - 0.00022 21.7 0.4 0.012 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKF93396.1 - 0.00069 19.4 0.1 0.0018 18.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KKF93396.1 - 0.001 18.7 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KKF93396.1 - 0.023 14.8 0.0 0.098 12.8 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.23 KKF93396.1 - 0.03 14.4 0.2 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KKF93396.1 - 0.053 13.9 0.0 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KKF93396.1 - 0.054 14.0 0.0 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KKF93396.1 - 0.07 13.3 1.1 0.25 11.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 KKF93396.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_31 PF13614.6 KKF93396.1 - 0.14 12.1 0.0 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain YIF1 PF03878.15 KKF93397.1 - 4.5e-83 278.4 1.4 5.7e-83 278.1 1.4 1.1 1 0 0 1 1 1 1 YIF1 HATPase_c PF02518.26 KKF93398.1 - 1.3e-21 77.2 0.0 6e-21 75.0 0.0 2.2 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKF93398.1 - 7.3e-19 68.0 0.7 2.3e-11 43.9 0.0 3.1 2 0 0 2 2 2 2 Response regulator receiver domain PAS PF00989.25 KKF93398.1 - 3.7e-10 39.8 0.1 1.7e-06 28.0 0.0 3.2 2 1 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KKF93398.1 - 6e-08 32.9 0.0 0.016 15.5 0.0 3.1 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 KKF93398.1 - 4.2e-07 29.9 0.0 0.016 15.2 0.0 3.2 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 KKF93398.1 - 8e-06 25.7 0.1 0.1 12.7 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KKF93398.1 - 9.7e-05 22.6 0.3 0.7 10.2 0.1 3.8 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.12 KKF93398.1 - 0.0092 16.3 1.9 5.9 7.3 0.2 3.7 4 1 0 4 4 4 2 PAS fold DUF1512 PF07431.12 KKF93398.1 - 0.078 12.0 4.0 0.055 12.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) MFS_1 PF07690.16 KKF93399.1 - 1.1e-22 80.5 53.4 8.1e-13 48.0 6.2 3.8 2 1 2 4 4 4 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KKF93399.1 - 3.3e-05 23.0 37.9 0.00027 19.9 4.3 3.8 3 2 1 4 4 4 2 Sugar (and other) transporter Ketoacyl-synt_C PF02801.22 KKF93400.1 - 3e-35 120.8 0.6 1.3e-34 118.7 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KKF93400.1 - 6.9e-32 111.2 1.0 1.9e-31 109.8 0.2 1.9 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.10 KKF93400.1 - 3.8e-25 88.9 0.0 9.1e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 KR domain KAsynt_C_assoc PF16197.5 KKF93400.1 - 6.6e-15 55.5 0.0 1.5e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ketoacyl-synt PF00109.26 KKF93400.1 - 7.9e-09 35.5 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 KKF93400.1 - 0.00029 21.1 0.1 0.00094 19.5 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 KKF93400.1 - 0.00046 20.0 1.4 0.015 15.0 1.4 2.4 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis adh_short PF00106.25 KKF93400.1 - 0.0095 15.4 0.0 0.028 13.9 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans_2 PF11951.8 KKF93401.1 - 2.4e-14 53.0 2.9 2.5e-14 52.9 2.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DbpA PF03880.15 KKF93402.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain PH PF00169.29 KKF93403.1 - 3e-06 27.7 0.0 9.2e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF4366 PF14283.6 KKF93403.1 - 0.17 11.9 2.1 15 5.6 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4366) Prominin PF05478.11 KKF93403.1 - 0.41 8.5 0.8 0.61 8.0 0.8 1.1 1 0 0 1 1 1 0 Prominin TctA PF01970.16 KKF93403.1 - 0.87 8.2 6.1 3.4 6.3 1.1 3.3 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctA family Xan_ur_permease PF00860.20 KKF93404.1 - 1.8e-23 82.9 32.1 2.4e-21 75.9 32.1 3.0 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 KKF93404.1 - 1.2 9.6 15.8 0.53 10.7 4.8 2.8 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Hydrolase_6 PF13344.6 KKF93406.1 - 4.4e-27 94.2 0.0 8.4e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKF93406.1 - 3.6e-14 52.6 0.1 7.7e-14 51.5 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KKF93406.1 - 2.6e-10 40.9 0.0 0.00094 19.5 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKF93406.1 - 2.4e-06 27.8 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 KKF93406.1 - 0.03 13.8 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Acid_phosphat_B PF03767.14 KKF93406.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PNK3P PF08645.11 KKF93406.1 - 0.1 12.3 0.4 0.62 9.8 0.2 2.1 2 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase DUF166 PF02593.14 KKF93406.1 - 0.15 11.6 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function PGP_phosphatase PF09419.10 KKF93406.1 - 0.19 11.4 0.1 12 5.4 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Topoisom_bac PF01131.20 KKF93407.1 - 2.6e-97 326.4 0.0 1.1e-96 324.4 0.0 1.7 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KKF93407.1 - 8.7e-19 67.7 0.0 2.3e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Toprim domain RdRP_1 PF00680.20 KKF93407.1 - 0.086 11.3 0.6 7.7 4.9 0.0 2.1 2 0 0 2 2 2 0 RNA dependent RNA polymerase zf-H2C2_2 PF13465.6 KKF93408.1 - 9.1e-06 25.9 6.5 1.6e-05 25.1 3.3 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KKF93408.1 - 2.1e-05 24.7 2.8 2.1e-05 24.7 2.8 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKF93408.1 - 6.7e-05 23.4 1.7 6.7e-05 23.4 1.7 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKF93408.1 - 0.00076 19.7 2.1 0.0023 18.1 0.7 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KKF93408.1 - 0.0024 17.8 1.3 0.005 16.8 1.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2HE PF16278.5 KKF93408.1 - 0.16 12.4 0.3 0.39 11.2 0.3 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KKF93408.1 - 1 9.7 3.0 0.65 10.4 0.2 2.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Glucosamine_iso PF01182.20 KKF93409.1 - 5.5e-69 232.5 0.0 6.2e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase KH_1 PF00013.29 KKF93410.1 - 1.5e-42 143.2 8.3 8.4e-17 60.8 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KKF93410.1 - 1.7e-08 34.2 4.2 0.037 13.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KKF93410.1 - 1.4e-07 31.3 10.7 0.018 14.9 0.4 3.5 3 1 0 3 3 3 3 KH domain KH_5 PF13184.6 KKF93410.1 - 8.9e-06 25.7 4.3 0.13 12.3 0.0 3.3 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.19 KKF93410.1 - 0.015 15.0 0.2 1.2 8.8 0.0 3.1 3 0 0 3 3 3 0 dUTPase DUF2263 PF10021.9 KKF93411.1 - 7.4e-11 42.6 0.0 1.4e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Sec23_trunk PF04811.15 KKF93412.1 - 9.7e-50 169.4 0.0 3e-49 167.8 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KKF93412.1 - 4.2e-21 74.7 0.0 7.2e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KKF93412.1 - 1.3e-17 64.3 0.0 2.1e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KKF93412.1 - 7.1e-15 54.8 5.8 1.9e-14 53.4 5.8 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KKF93412.1 - 5.3e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat PTA_PTB PF01515.19 KKF93412.1 - 0.12 11.7 0.0 0.4 10.0 0.0 1.8 2 0 0 2 2 2 0 Phosphate acetyl/butaryl transferase Lactamase_B_6 PF16661.5 KKF93413.1 - 7.1e-59 198.5 0.0 1.2e-58 197.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KKF93413.1 - 2.7e-38 131.8 1.5 3.6e-37 128.1 0.1 2.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KKF93413.1 - 5.3e-15 55.7 0.0 1.5e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KKF93413.1 - 3.9e-12 45.9 0.0 1.7e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain DUF3245 PF11595.8 KKF93413.1 - 1.1 9.8 9.5 2.8 8.4 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) SYS1 PF09801.9 KKF93414.1 - 4.5e-36 124.2 0.3 5.1e-36 124.0 0.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX6B PF02297.17 KKF93415.1 - 3.4e-22 78.5 2.4 4.2e-22 78.2 2.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb PIP5K PF01504.18 KKF93416.1 - 1.7e-102 342.3 1.0 4.8e-102 340.9 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Acyl-CoA_dh_1 PF00441.24 KKF93419.1 - 1.6e-43 148.5 0.3 2.3e-43 148.0 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKF93419.1 - 1.1e-20 73.6 0.0 2.2e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KKF93419.1 - 1.3e-19 70.1 0.1 2.5e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KKF93419.1 - 3.9e-18 66.2 0.0 9.5e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KKF93419.1 - 1.5e-09 38.2 0.0 2.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_I PF00867.18 KKF93420.1 - 1.2e-28 99.3 0.8 2e-28 98.6 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KKF93420.1 - 5.5e-27 94.2 0.0 7e-26 90.7 0.0 2.5 1 1 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KKF93420.1 - 5.6e-05 23.7 0.1 0.00029 21.4 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KKF93420.1 - 0.039 14.1 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Cupredoxin_1 PF13473.6 KKF93421.1 - 0.092 12.9 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 Cupredoxin-like domain XFP_N PF09364.10 KKF93422.1 - 8.2e-162 538.1 0.0 1.1e-161 537.7 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 KKF93422.1 - 8.7e-83 276.3 0.0 1.6e-82 275.5 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 KKF93422.1 - 1.1e-74 250.3 0.0 1.8e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain Ceramidase_alk PF04734.13 KKF93423.1 - 3.3e-205 682.5 0.0 3.9e-205 682.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KKF93423.1 - 2.3e-56 190.3 0.0 3.9e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal SIS PF01380.22 KKF93424.1 - 1e-11 44.8 0.1 8.3e-11 41.9 0.1 2.3 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KKF93424.1 - 0.0016 18.4 0.1 0.2 11.7 0.3 2.4 1 1 1 2 2 2 2 SIS domain CIAPIN1 PF05093.13 KKF93425.1 - 5e-40 136.1 1.0 7.7e-40 135.5 1.0 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KKF93425.1 - 3e-29 101.9 0.0 4.2e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Peptidase_S10 PF00450.22 KKF93426.1 - 6.7e-113 378.2 0.0 8.1e-113 378.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_Me_trans PF04252.13 KKF93427.1 - 1.5e-82 276.0 0.0 1.7e-82 275.9 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase zf-C2H2_11 PF16622.5 KKF93428.1 - 0.46 10.3 5.7 1.1 9.0 5.7 1.7 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KKF93428.1 - 1 10.4 2.9 3.1 8.9 2.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Sugar_tr PF00083.24 KKF93429.1 - 8.6e-15 54.5 5.0 1e-14 54.2 5.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF93429.1 - 1.4e-09 37.3 9.7 1.6e-09 37.2 9.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KKF93429.1 - 4.6e-05 21.9 1.3 5.4e-05 21.7 0.3 1.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KKF93429.1 - 0.041 12.7 5.0 0.049 12.5 5.0 1.0 1 0 0 1 1 1 0 MFS_1 like family Iso_dh PF00180.20 KKF93430.1 - 1e-79 268.2 0.0 1.2e-79 268.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GTP_CH_N PF12471.8 KKF93431.1 - 2.5e-87 291.6 0.0 3.4e-87 291.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KKF93431.1 - 1.1e-16 60.8 0.0 1.9e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF1688 PF07958.11 KKF93432.1 - 2.7e-112 375.6 0.0 1.7e-72 244.5 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1688) UPRTase PF14681.6 KKF93433.1 - 3e-49 167.3 0.0 1.8e-46 158.2 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KKF93433.1 - 1e-06 28.4 0.0 1.7e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Aldedh PF00171.22 KKF93434.1 - 1.7e-52 178.5 0.0 2.3e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UPRTase PF14681.6 KKF93434.1 - 9.1e-52 175.5 0.0 1.4e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KKF93434.1 - 0.017 14.6 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase domain FA_desaturase PF00487.24 KKF93435.1 - 3.5e-18 66.4 26.0 3e-17 63.3 26.0 2.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KKF93435.1 - 2e-05 24.8 0.0 4.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Pyr_redox_2 PF07992.14 KKF93436.1 - 6.9e-47 160.1 1.7 1e-46 159.5 1.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KKF93436.1 - 6.7e-16 58.0 0.0 1.5e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KKF93436.1 - 2.3e-10 40.9 3.6 4e-09 36.9 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KKF93436.1 - 3.3e-07 30.2 0.0 1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.6 KKF93436.1 - 5.7e-06 26.4 0.4 0.047 13.7 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Reductase_C PF14759.6 KKF93436.1 - 3.4e-05 24.3 0.0 7.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 KKF93436.1 - 0.057 12.6 0.0 5 6.2 0.0 2.2 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) eIF2A PF08662.11 KKF93437.1 - 1.5e-36 126.1 1.2 7.8e-33 114.0 0.0 3.8 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KKF93437.1 - 2.8e-06 27.1 0.0 6.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KKF93437.1 - 0.099 13.6 0.3 10 7.2 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Methyltr_RsmF_N PF17125.5 KKF93437.1 - 0.25 11.9 1.2 1.5 9.3 0.0 3.0 5 0 0 5 5 5 0 N-terminal domain of 16S rRNA methyltransferase RsmF Cpn60_TCP1 PF00118.24 KKF93438.1 - 4.8e-131 437.8 10.5 5.4e-131 437.6 10.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 KKF93438.1 - 0.023 14.9 0.2 0.063 13.5 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 KKF93438.1 - 0.083 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat RabGAP-TBC PF00566.18 KKF93439.1 - 4.2e-11 42.9 0.0 9.5e-11 41.8 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PQ-loop PF04193.14 KKF93440.1 - 1.5e-15 56.6 0.1 2.9e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 PQ loop repeat DCP1 PF06058.13 KKF93441.1 - 3.3e-24 85.1 0.1 5.8e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family TFIIA PF03153.13 KKF93441.1 - 0.0027 17.8 7.8 0.0027 17.8 7.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Tubulin_3 PF14881.6 KKF93441.1 - 0.078 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain BAR PF03114.18 KKF93442.1 - 1.2e-67 228.0 3.3 1.5e-67 227.7 3.3 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KKF93442.1 - 0.0036 18.0 0.3 0.023 15.5 0.0 2.5 3 1 0 3 3 3 1 CP12 domain HAUS-augmin3 PF14932.6 KKF93442.1 - 0.039 13.5 0.6 0.29 10.7 0.1 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2884 PF11101.8 KKF93442.1 - 0.2 11.1 2.4 5.6 6.4 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2884) Pept_tRNA_hydro PF01195.19 KKF93443.1 - 6.7e-23 81.5 0.0 7.6e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Stealth_CR3 PF17102.5 KKF93443.1 - 0.12 12.3 0.1 0.42 10.6 0.1 1.9 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 zf-Mss51 PF13824.6 KKF93444.1 - 2e-25 88.7 6.6 3.6e-25 87.8 6.6 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KKF93444.1 - 0.0012 18.9 0.9 0.0012 18.9 0.9 1.7 2 0 0 2 2 2 1 MYND finger Lectin_leg-like PF03388.13 KKF93445.1 - 1.3e-24 86.8 0.0 2.4e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Legume-like lectin family Med15 PF09606.10 KKF93445.1 - 0.00041 19.2 13.4 0.00049 18.9 13.4 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal eIF-3_zeta PF05091.12 KKF93445.1 - 0.001 18.2 4.7 0.004 16.2 4.7 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 KKF93445.1 - 0.0011 19.1 19.8 0.0014 18.7 19.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KKF93445.1 - 0.0015 18.2 28.4 0.0025 17.4 28.4 1.3 1 0 0 1 1 1 1 Spt20 family DUF4175 PF13779.6 KKF93445.1 - 0.0015 16.5 15.7 0.0018 16.3 15.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) SpoIIP PF07454.11 KKF93445.1 - 0.042 13.3 8.3 0.061 12.8 8.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4820 PF16091.5 KKF93445.1 - 0.049 13.0 7.3 0.089 12.1 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Neur_chan_memb PF02932.16 KKF93445.1 - 0.099 12.7 1.5 0.13 12.3 1.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KKF93445.1 - 0.13 11.0 7.7 0.16 10.7 7.7 1.1 1 0 0 1 1 1 0 Presenilin Dehalogenase PF13486.6 KKF93445.1 - 0.13 11.6 3.8 0.21 10.9 3.8 1.3 1 0 0 1 1 1 0 Reductive dehalogenase subunit CLN3 PF02487.17 KKF93445.1 - 0.14 11.2 2.2 0.18 10.8 2.2 1.2 1 0 0 1 1 1 0 CLN3 protein TMEM51 PF15345.6 KKF93445.1 - 0.15 11.9 7.0 0.21 11.4 7.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4834 PF16118.5 KKF93445.1 - 0.22 12.5 10.5 0.51 11.3 10.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SID-1_RNA_chan PF13965.6 KKF93445.1 - 0.29 9.5 2.2 0.38 9.1 2.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PepSY_TM PF03929.16 KKF93445.1 - 0.4 10.3 2.6 0.53 9.9 2.6 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Peptidase_S15 PF02129.18 KKF93445.1 - 0.6 9.7 6.9 0.92 9.0 6.9 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Pex14_N PF04695.13 KKF93445.1 - 0.69 10.6 14.9 1.1 9.9 14.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 KKF93445.1 - 0.96 9.2 4.0 1.5 8.5 4.0 1.2 1 0 0 1 1 1 0 Connexin G0-G1_switch_2 PF15103.6 KKF93445.1 - 1.3 9.4 5.5 3.1 8.3 5.5 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF2722 PF10846.8 KKF93445.1 - 1.5 7.7 34.5 0.27 10.2 28.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) ORC_WH_C PF18137.1 KKF93445.1 - 1.6 8.8 8.3 3 7.9 8.3 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal FAM76 PF16046.5 KKF93445.1 - 1.9 7.8 17.7 3.3 7.0 17.7 1.3 1 0 0 1 1 1 0 FAM76 protein ATP-synt_G PF04718.15 KKF93445.1 - 1.9 9.4 8.9 4.2 8.2 8.9 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit Pox_Ag35 PF03286.14 KKF93445.1 - 2.7 7.8 17.2 16 5.2 17.2 1.8 1 1 0 1 1 1 0 Pox virus Ag35 surface protein FHIPEP PF00771.20 KKF93445.1 - 3.1 6.2 10.5 7 5.0 10.5 1.6 1 1 0 1 1 1 0 FHIPEP family PAE PF03283.13 KKF93445.1 - 3.5 6.7 10.6 4.8 6.2 10.6 1.2 1 0 0 1 1 1 0 Pectinacetylesterase DUF3381 PF11861.8 KKF93445.1 - 4.3 7.1 14.8 48 3.7 16.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Baculo_PP31 PF05311.11 KKF93445.1 - 6 6.3 14.3 1.2 8.5 10.0 1.8 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Activator_LAG-3 PF11498.8 KKF93445.1 - 7.8 5.3 34.6 11 4.8 34.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AIF_C PF14721.6 KKF93445.1 - 8.6 6.7 8.7 12 6.3 7.3 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Peptidase_M24 PF00557.24 KKF93446.1 - 6.5e-59 199.1 0.0 9.4e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KKF93446.1 - 4.8e-21 74.8 0.0 8.9e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HET PF06985.11 KKF93447.1 - 5.3e-22 78.7 0.0 1e-21 77.8 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CENP-T_C PF15511.6 KKF93448.1 - 3.5e-33 114.0 0.0 1.2e-32 112.3 0.0 1.9 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KKF93448.1 - 5.6e-10 39.5 0.0 1.2e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KKF93448.1 - 0.0029 18.0 0.0 0.0067 16.8 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KKF93448.1 - 0.037 14.0 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated Lyase_1 PF00206.20 KKF93449.1 - 1.2e-112 376.4 0.0 1.6e-112 375.9 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KKF93449.1 - 1.8e-22 79.5 0.1 4.5e-22 78.2 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Luteo_PO PF04662.13 KKF93449.1 - 0.097 12.3 0.0 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 Luteovirus P0 protein EAF PF09816.9 KKF93450.1 - 2e-20 73.0 0.1 4.3e-20 72.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor MmgE_PrpD PF03972.14 KKF93451.1 - 3.3e-70 236.8 0.0 3.7e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RVT_1 PF00078.27 KKF93453.1 - 1.6e-33 116.1 0.0 2.7e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KKF93453.1 - 1e-12 48.4 0.0 2.5e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KKF93453.1 - 0.001 18.9 0.7 0.0032 17.3 0.3 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like FIVAR PF07554.13 KKF93453.1 - 2.2 9.1 4.8 1.5 9.6 0.0 2.9 3 0 0 3 3 3 0 FIVAR domain Nfu_N PF08712.11 KKF93455.1 - 3.4e-28 97.5 0.1 2.8e-27 94.6 0.1 2.3 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KKF93455.1 - 1.8e-25 88.9 0.1 3.3e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 KKF93455.1 - 0.11 12.6 1.6 0.25 11.5 1.1 1.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus zf-HIT PF04438.16 KKF93456.1 - 2.8e-08 33.5 10.4 4.4e-08 32.8 10.4 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KKF93456.1 - 0.12 12.5 10.5 0.22 11.6 10.5 1.4 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.24 KKF93456.1 - 0.24 11.6 6.2 0.4 10.9 6.2 1.3 1 0 0 1 1 1 0 B-box zinc finger PolC_DP2 PF03833.13 KKF93456.1 - 0.68 7.7 2.6 0.84 7.4 2.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Glycoprotein PF03409.15 KKF93457.1 - 0.46 9.3 9.6 0.023 13.5 4.2 1.5 2 0 0 2 2 2 0 Transmembrane glycoprotein PRMT5_TIM PF17285.2 KKF93458.1 - 3.5e-40 137.8 0.0 5.3e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 KKF93458.1 - 1.9e-32 112.6 0.0 6.7e-32 110.8 0.0 1.9 2 0 0 2 2 2 1 PRMT5 oligomerisation domain PRMT5 PF05185.16 KKF93458.1 - 1.9e-20 73.4 0.0 6.6e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase AP_endonuc_2 PF01261.24 KKF93458.1 - 0.19 11.1 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel OB_NTP_bind PF07717.16 KKF93459.1 - 6.6e-22 77.7 0.0 3.9e-21 75.2 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KKF93459.1 - 3.3e-19 69.1 0.0 7.7e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKF93459.1 - 6.2e-12 45.8 0.0 4.6e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKF93459.1 - 2.6e-08 33.8 0.1 6.9e-08 32.5 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKF93459.1 - 2.5e-05 24.6 0.0 7.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF93459.1 - 0.002 18.5 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KKF93459.1 - 0.0048 16.6 0.1 0.017 14.8 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KKF93459.1 - 0.0066 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKF93459.1 - 0.0084 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KKF93459.1 - 0.074 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA PF00004.29 KKF93459.1 - 0.19 12.1 1.7 1.6 9.2 1.7 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ICE2 PF08426.10 KKF93460.1 - 8.9e-148 492.7 12.6 1e-147 492.5 12.6 1.0 1 0 0 1 1 1 1 ICE2 UCR_14kD PF02271.16 KKF93461.1 - 3.2e-38 129.7 0.6 3.7e-38 129.5 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Anp1 PF03452.14 KKF93462.1 - 3.5e-87 292.2 0.1 1.9e-66 224.2 0.0 2.1 1 1 1 2 2 2 2 Anp1 DUF4550 PF15084.6 KKF93462.1 - 0.094 13.1 0.6 16 6.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) Herpes_UL17 PF04559.12 KKF93463.1 - 0.018 13.8 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein GDE_C PF06202.14 KKF93463.1 - 0.048 12.6 0.1 0.065 12.2 0.1 1.1 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Mst1_SARAH PF11629.8 KKF93463.1 - 0.21 11.7 0.6 9.4 6.4 0.1 2.3 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 PMT PF02366.18 KKF93464.1 - 1.2e-85 287.1 12.2 1.2e-85 287.1 12.2 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KKF93464.1 - 1.6e-65 220.4 14.8 1.6e-65 220.4 14.8 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KKF93464.1 - 1.9e-35 122.4 0.9 2.9e-35 121.8 0.9 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.8 KKF93464.1 - 9.4 6.1 7.1 0.87 9.4 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Ras PF00071.22 KKF93465.1 - 4.9e-49 166.1 0.0 7.4e-38 129.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKF93465.1 - 1.6e-28 99.3 0.0 2.9e-18 66.2 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF93465.1 - 5.3e-09 35.8 0.0 2.9e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKF93465.1 - 1e-05 25.2 0.0 9.7e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKF93465.1 - 0.00046 20.2 0.0 0.003 17.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKF93465.1 - 0.0015 17.9 0.0 0.0044 16.4 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKF93465.1 - 0.0077 16.2 0.0 0.8 9.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KKF93465.1 - 0.16 12.3 0.0 0.83 9.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain Peroxin-3 PF04882.12 KKF93465.1 - 0.16 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Peroxin-3 Choline_transpo PF04515.12 KKF93466.1 - 9.4e-31 107.2 19.2 9.4e-31 107.2 19.2 2.4 2 1 0 2 2 2 1 Plasma-membrane choline transporter WW PF00397.26 KKF93467.1 - 5.4e-09 36.0 6.7 5.4e-09 36.0 6.7 2.1 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.9 KKF93467.1 - 0.0032 17.5 17.3 0.0032 17.5 17.3 2.9 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) CCDC50_N PF15295.6 KKF93467.1 - 0.078 13.1 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF2012 PF09430.10 KKF93468.1 - 1.3e-26 93.1 0.0 1.8e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Auts2 PF15336.6 KKF93468.1 - 0.2 11.8 0.5 0.29 11.2 0.5 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Cys_Met_Meta_PP PF01053.20 KKF93469.1 - 1.9e-148 494.1 0.0 2.2e-148 493.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KKF93469.1 - 3e-09 36.5 0.1 5.2e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KKF93469.1 - 1.5e-08 34.4 0.2 2.5e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KKF93469.1 - 4.1e-08 32.6 0.6 6e-08 32.0 0.1 1.4 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KKF93469.1 - 4e-05 23.0 0.0 7.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KKF93469.1 - 0.0056 15.3 0.0 0.0074 14.9 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase ABC_sub_bind PF04392.12 KKF93469.1 - 0.033 13.4 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter substrate binding protein Asparaginase_C PF17763.1 KKF93469.1 - 0.035 14.3 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 KKF93469.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein MccV PF17508.2 KKF93469.1 - 2.1 8.9 4.4 0.63 10.6 0.4 2.2 2 0 0 2 2 2 0 Microcin V bacteriocin AMP-binding PF00501.28 KKF93470.1 - 6.9e-89 298.3 0.0 8.2e-89 298.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RRM_1 PF00076.22 KKF93471.1 - 6e-07 29.2 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2613 PF11021.8 KKF93471.1 - 1.6 8.9 6.1 12 6.1 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Citrate_synt PF00285.21 KKF93472.1 - 1.7e-101 339.9 0.0 2.2e-101 339.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KKF93472.1 - 0.028 14.1 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 KKF93473.1 - 5.4e-27 93.6 7.0 4.6e-13 48.9 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.20 KKF93474.1 - 2.3e-46 157.6 3.8 2.3e-46 157.6 3.8 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKF93474.1 - 1.5e-16 61.3 0.0 3.5e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKF93474.1 - 1.4e-09 37.5 0.0 3.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKF93474.1 - 0.0071 16.1 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase O-antigen_lig PF13425.6 KKF93474.1 - 0.096 11.5 5.5 0.07 11.9 3.3 1.8 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Phage_fiber_C PF06820.12 KKF93474.1 - 0.11 12.9 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 Putative prophage tail fibre C-terminus Cation_ATPase PF13246.6 KKF93474.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF2613 PF11021.8 KKF93474.1 - 1.7 8.9 6.9 4.2 7.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF3425 PF11905.8 KKF93476.1 - 9.5e-15 54.7 0.0 1.7e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) zf-CCHC PF00098.23 KKF93477.1 - 0.00047 20.1 0.8 0.00084 19.3 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 KKF93477.1 - 0.0035 17.0 1.2 0.0062 16.2 1.2 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_5 PF14787.6 KKF93477.1 - 0.32 10.8 3.8 0.57 9.9 3.8 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Pec_lyase_C PF00544.19 KKF93479.1 - 2.6e-43 148.1 6.6 4.4e-43 147.3 6.6 1.3 1 0 0 1 1 1 1 Pectate lyase CENP-B_dimeris PF09026.10 KKF93479.1 - 0.06 13.7 4.3 0.15 12.5 4.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Spore_YtfJ PF09579.10 KKF93479.1 - 9.7 6.4 9.3 21 5.3 8.5 2.1 1 1 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Alginate_lyase PF05426.12 KKF93480.1 - 1.2e-10 41.4 2.9 2.8e-10 40.2 2.9 1.5 1 1 0 1 1 1 1 Alginate lyase DUF1221 PF06760.11 KKF93481.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Cep57_MT_bd PF06657.13 KKF93483.1 - 0.0036 17.7 1.4 0.011 16.2 1.6 1.7 1 1 1 2 2 2 1 Centrosome microtubule-binding domain of Cep57 FPP PF05911.11 KKF93483.1 - 0.0046 15.2 2.6 0.0059 14.9 2.6 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil BST2 PF16716.5 KKF93483.1 - 0.0068 17.0 2.9 0.031 14.8 0.9 2.2 1 1 1 2 2 2 1 Bone marrow stromal antigen 2 Laminin_I PF06008.14 KKF93483.1 - 0.0086 15.8 0.4 0.011 15.4 0.4 1.1 1 0 0 1 1 1 1 Laminin Domain I YabA PF06156.13 KKF93483.1 - 0.033 14.8 0.2 0.046 14.4 0.2 1.3 1 0 0 1 1 1 0 Initiation control protein YabA FmiP_Thoc5 PF09766.9 KKF93483.1 - 0.07 12.4 1.6 0.1 11.9 1.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 MS_channel PF00924.18 KKF93483.1 - 0.18 11.3 0.4 5 6.6 0.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel DUF2046 PF09755.9 KKF93484.1 - 7.6e-05 22.1 8.0 0.0028 17.0 8.0 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DUF5082 PF16888.5 KKF93484.1 - 0.00039 20.7 15.4 0.046 14.0 0.4 4.3 2 2 2 4 4 4 1 Domain of unknown function (DUF5082) CLZ PF16526.5 KKF93484.1 - 0.00059 20.1 10.5 0.092 13.1 4.0 3.3 3 1 0 3 3 3 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4201 PF13870.6 KKF93484.1 - 0.0025 17.6 12.1 0.014 15.1 6.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) HAP1_N PF04849.13 KKF93484.1 - 0.0033 16.7 10.5 0.014 14.7 4.2 2.7 2 2 0 2 2 2 1 HAP1 N-terminal conserved region ADIP PF11559.8 KKF93484.1 - 0.0037 17.4 16.6 0.089 12.9 8.4 2.5 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KKF93484.1 - 0.005 16.9 12.5 0.3 11.1 1.1 2.5 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 KKF93484.1 - 0.0053 15.5 8.8 0.0082 14.9 8.8 1.2 1 0 0 1 1 1 1 AAA domain SHE3 PF17078.5 KKF93484.1 - 0.0058 16.4 9.4 0.016 14.9 3.4 2.4 2 1 0 2 2 2 1 SWI5-dependent HO expression protein 3 SPATA1_C PF15743.5 KKF93484.1 - 0.0081 16.2 11.3 0.14 12.2 2.0 3.4 1 1 2 3 3 3 1 Spermatogenesis-associated C-terminus CCDC92 PF14916.6 KKF93484.1 - 0.0096 15.7 1.8 2 8.2 0.0 3.0 3 0 0 3 3 2 1 Coiled-coil domain of unknown function Hemagglutinin PF00509.18 KKF93484.1 - 0.011 14.2 0.0 0.052 12.0 0.0 1.9 2 0 0 2 2 2 0 Haemagglutinin TolA_bind_tri PF16331.5 KKF93484.1 - 0.019 15.0 8.0 3.2 7.9 1.0 4.3 3 1 1 4 4 4 0 TolA binding protein trimerisation Lebercilin PF15619.6 KKF93484.1 - 0.028 14.1 15.4 0.025 14.3 6.8 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4200 PF13863.6 KKF93484.1 - 0.03 14.7 16.5 0.41 11.1 8.1 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) DUF842 PF05811.13 KKF93484.1 - 0.03 14.0 1.5 8 6.2 0.2 2.8 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) BicD PF09730.9 KKF93484.1 - 0.034 12.6 15.3 0.63 8.4 15.0 2.2 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D GAS PF13851.6 KKF93484.1 - 0.035 13.5 12.5 0.049 13.0 5.7 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KKF93484.1 - 0.037 14.2 18.2 0.053 13.7 10.2 3.1 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF812 PF05667.11 KKF93484.1 - 0.038 12.9 18.9 0.075 11.9 10.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Spc7 PF08317.11 KKF93484.1 - 0.045 12.6 18.3 0.35 9.7 13.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Fungal_TACC PF12709.7 KKF93484.1 - 0.056 13.9 6.8 1.6 9.2 2.3 3.3 2 1 0 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins BRCT PF00533.26 KKF93484.1 - 0.067 13.6 0.1 0.24 11.8 0.0 1.9 2 0 0 2 2 1 0 BRCA1 C Terminus (BRCT) domain GIT_CC PF16559.5 KKF93484.1 - 0.071 13.0 5.0 4.5 7.2 0.9 3.6 3 1 1 4 4 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 KKF93484.1 - 0.086 13.2 16.2 0.84 10.1 2.5 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) HALZ PF02183.18 KKF93484.1 - 0.092 13.0 9.3 1.1 9.5 3.4 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KKF93484.1 - 0.1 12.7 13.1 11 6.2 0.0 4.4 3 1 1 4 4 4 0 bZIP transcription factor DUF4407 PF14362.6 KKF93484.1 - 0.1 11.9 17.4 13 5.0 17.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 KKF93484.1 - 0.1 12.7 7.1 1.4 9.2 0.0 3.4 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 ABC_tran_CTD PF16326.5 KKF93484.1 - 0.12 12.6 18.6 5.3 7.4 0.5 4.1 2 2 1 3 3 3 0 ABC transporter C-terminal domain LPP PF04728.13 KKF93484.1 - 0.12 12.8 6.8 10 6.6 2.0 3.9 2 2 1 3 3 2 0 Lipoprotein leucine-zipper Not3 PF04065.15 KKF93484.1 - 0.13 11.6 13.6 1.1 8.7 4.3 3.3 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF1192 PF06698.11 KKF93484.1 - 0.14 12.2 16.7 0.23 11.5 0.3 4.8 4 1 0 5 5 4 0 Protein of unknown function (DUF1192) MbeD_MobD PF04899.12 KKF93484.1 - 0.18 12.0 4.3 2.5 8.3 0.0 3.1 2 1 0 2 2 2 0 MbeD/MobD like SlyX PF04102.12 KKF93484.1 - 0.2 12.3 9.6 20 5.9 0.1 4.5 2 2 1 4 4 4 0 SlyX DUF4140 PF13600.6 KKF93484.1 - 0.21 12.1 19.4 3.2 8.3 0.3 4.2 1 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) KASH_CCD PF14662.6 KKF93484.1 - 0.21 11.4 9.8 1.1 9.1 3.7 2.4 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Uso1_p115_C PF04871.13 KKF93484.1 - 0.22 11.9 27.3 0.24 11.8 5.2 2.7 2 1 0 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 KKF93484.1 - 0.23 12.1 7.6 13 6.5 0.1 3.0 2 1 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 KKF93484.1 - 0.25 11.8 17.5 29 5.2 1.2 4.0 1 1 1 2 2 2 0 Cell division protein ZapB FlaC_arch PF05377.11 KKF93484.1 - 0.25 11.7 4.3 28 5.2 0.6 3.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 KKF93484.1 - 0.34 10.2 9.7 0.33 10.2 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 KKF93484.1 - 0.37 10.8 7.0 5.7 7.0 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF848 PF05852.11 KKF93484.1 - 0.38 10.9 8.8 0.35 11.0 1.0 3.0 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) MRPL52 PF18699.1 KKF93484.1 - 0.41 10.9 14.5 9.5 6.5 7.0 3.5 2 1 1 3 3 3 0 Mitoribosomal protein mL52 DivIC PF04977.15 KKF93484.1 - 0.45 10.3 17.3 1.7 8.5 0.1 4.5 3 1 1 4 4 4 0 Septum formation initiator PRKG1_interact PF15898.5 KKF93484.1 - 0.46 11.4 25.9 0.31 12.0 0.9 4.2 3 2 0 3 3 2 0 cGMP-dependent protein kinase interacting domain Vps5 PF09325.10 KKF93484.1 - 0.55 9.7 10.6 2.8 7.4 6.0 3.0 2 1 0 2 2 2 0 Vps5 C terminal like TPR_MLP1_2 PF07926.12 KKF93484.1 - 0.61 10.1 24.9 0.095 12.8 7.6 3.7 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 KKF93484.1 - 0.62 10.4 16.9 2.4e+02 2.0 16.7 2.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF2203 PF09969.9 KKF93484.1 - 0.83 10.4 12.1 0.39 11.4 3.5 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) MIP-T3_C PF17749.1 KKF93484.1 - 0.84 9.6 9.1 7.1 6.6 3.6 3.3 1 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Pox_A_type_inc PF04508.12 KKF93484.1 - 0.84 9.6 5.5 9.9 6.2 0.1 4.2 4 1 1 5 5 4 0 Viral A-type inclusion protein repeat ACCA PF03255.14 KKF93484.1 - 0.86 9.5 7.0 7.8 6.4 2.4 2.6 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit BLOC1_2 PF10046.9 KKF93484.1 - 0.86 9.9 4.4 3.5 8.0 1.3 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.14 KKF93484.1 - 0.86 9.9 15.3 55 4.1 14.6 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ApoLp-III PF07464.11 KKF93484.1 - 0.93 9.6 7.4 1.6 8.8 0.3 2.4 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) UPF0242 PF06785.11 KKF93484.1 - 0.98 9.5 13.7 6 6.9 0.6 2.3 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KKF93484.1 - 1.2 9.7 5.6 1.7e+02 2.8 5.6 3.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 Flagellin_N PF00669.20 KKF93484.1 - 1.2 9.3 6.1 1.7 8.8 0.2 3.1 1 1 1 3 3 2 0 Bacterial flagellin N-terminal helical region DUF4618 PF15397.6 KKF93484.1 - 1.4 8.3 9.7 7.7 5.8 4.1 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) Fib_alpha PF08702.10 KKF93484.1 - 1.6 8.9 5.8 7.8 6.7 1.4 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 KKF93484.1 - 1.6 9.0 15.3 6.8 7.0 7.3 3.0 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Rho_Binding PF08912.11 KKF93484.1 - 1.6 9.6 11.7 12 6.8 0.5 3.9 2 2 2 4 4 3 0 Rho Binding End3 PF12761.7 KKF93484.1 - 1.8 8.7 22.3 0.77 9.9 3.4 2.7 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Spc24 PF08286.11 KKF93484.1 - 1.9 8.8 13.2 5.4 7.3 2.0 3.7 2 2 1 3 3 3 0 Spc24 subunit of Ndc80 EzrA PF06160.12 KKF93484.1 - 2.1 6.4 9.5 0.26 9.4 3.5 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Acyl-CoA_dh_2 PF08028.11 KKF93484.1 - 2.5 8.4 6.6 2.1 8.6 0.3 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain She9_MDM33 PF05546.11 KKF93484.1 - 2.6 7.8 11.7 0.55 10.0 6.0 2.3 2 1 0 2 2 2 0 She9 / Mdm33 family CorA PF01544.18 KKF93484.1 - 2.9 7.1 6.3 5 6.4 0.3 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Tup_N PF08581.10 KKF93484.1 - 3.4 8.0 10.9 7.6 6.9 6.6 2.8 2 1 0 2 2 2 0 Tup N-terminal FapA PF03961.13 KKF93484.1 - 3.7 6.1 11.4 1.8 7.1 5.3 2.0 1 1 0 2 2 2 0 Flagellar Assembly Protein A ApoO PF09769.9 KKF93484.1 - 4.2 7.3 6.7 17 5.3 0.1 3.3 1 1 1 2 2 2 0 Apolipoprotein O COG2 PF06148.11 KKF93484.1 - 4.4 7.4 8.4 11 6.1 0.4 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Lzipper-MIP1 PF14389.6 KKF93484.1 - 4.5 7.6 15.6 19 5.7 3.2 4.0 2 2 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DUF1204 PF06721.11 KKF93484.1 - 6.2 6.2 12.5 7.6 5.9 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1204) Phage_Mu_Gam PF07352.12 KKF93484.1 - 6.5 6.6 11.4 1.5 8.7 5.5 2.7 2 2 0 2 2 2 0 Bacteriophage Mu Gam like protein APG6_N PF17675.1 KKF93484.1 - 7 7.2 23.7 35 4.9 14.3 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2807 PF10988.8 KKF93485.1 - 1.6 8.5 13.1 0.3 10.9 7.3 2.1 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain GREB1 PF15782.5 KKF93485.1 - 8.2 3.4 35.0 12 2.9 35.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TRF PF08558.10 KKF93486.1 - 1.4e-21 77.2 2.3 3.5e-21 75.9 2.3 1.7 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KKF93486.1 - 5.8e-05 23.2 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Aldedh PF00171.22 KKF93487.1 - 1.7e-186 620.3 0.0 1.9e-186 620.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_76 PF03663.14 KKF93488.1 - 1.4e-132 442.7 3.0 1.6e-132 442.5 3.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KKF93488.1 - 0.013 14.6 8.7 0.037 13.1 3.7 2.9 1 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 KKF93488.1 - 0.056 12.7 0.1 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_127 PF07944.12 KKF93488.1 - 0.084 11.4 0.6 0.22 10.0 0.0 1.8 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 PI-PLC-X PF00388.19 KKF93489.1 - 8e-08 32.0 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Rep_fac_C PF08542.11 KKF93489.1 - 0.07 13.6 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain Glu-tRNAGln PF02686.15 KKF93490.1 - 0.00011 22.4 0.1 0.00031 21.0 0.1 1.7 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Creb_binding PF09030.10 KKF93490.1 - 0.042 14.5 0.7 0.083 13.6 0.7 1.5 1 0 0 1 1 1 0 Creb binding Shisa PF13908.6 KKF93491.1 - 0.15 12.2 1.1 0.16 12.2 1.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PHO4 PF01384.20 KKF93491.1 - 0.44 9.5 8.2 0.51 9.3 8.2 1.1 1 0 0 1 1 1 0 Phosphate transporter family SLATT_1 PF18181.1 KKF93491.1 - 2.2 8.2 7.4 2.7 7.9 7.4 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Polyoma_coat2 PF00761.20 KKF93491.1 - 3 7.5 8.9 3.6 7.2 8.9 1.0 1 0 0 1 1 1 0 Polyomavirus coat protein DUF726 PF05277.12 KKF93492.1 - 1.1e-16 60.8 0.0 1.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DENN PF02141.21 KKF93493.1 - 2.8e-46 157.8 0.0 8.9e-45 152.9 0.0 2.3 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KKF93493.1 - 2e-13 50.9 0.0 4.4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KKF93493.1 - 0.09 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 dDENN domain SPA PF08616.10 KKF93493.1 - 0.18 11.7 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis PAS_12 PF18095.1 KKF93493.1 - 0.22 11.1 0.0 0.49 10.0 0.0 1.5 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain C1_2 PF03107.16 KKF93493.1 - 0.33 11.3 1.0 0.68 10.3 1.0 1.4 1 0 0 1 1 1 0 C1 domain E1_DerP2_DerF2 PF02221.15 KKF93494.1 - 7.1e-26 91.2 0.2 8.4e-26 91.0 0.2 1.1 1 0 0 1 1 1 1 ML domain ATP-synt_F PF01990.17 KKF93495.1 - 4.1e-34 116.8 0.1 4.7e-34 116.6 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2418 PF10332.9 KKF93496.1 - 3.9e-35 120.3 0.6 5.1e-34 116.7 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2418) DUF3278 PF11683.8 KKF93496.1 - 0.16 12.0 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) HeLo PF14479.6 KKF93497.1 - 1.1e-14 54.8 1.6 1.5e-14 54.3 0.3 1.9 2 0 0 2 2 2 1 Prion-inhibition and propagation NACHT PF05729.12 KKF93497.1 - 3e-08 33.8 0.0 7.4e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KKF93497.1 - 0.0017 18.6 0.0 0.01 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KKF93497.1 - 0.0054 17.2 0.0 0.025 15.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KKF93497.1 - 0.017 14.3 0.0 0.05 12.8 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KKF93497.1 - 0.021 15.2 0.0 0.064 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain HTH_6 PF01418.17 KKF93497.1 - 0.042 13.8 2.2 3.3 7.7 0.1 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family DUF4130 PF13566.6 KKF93497.1 - 0.085 12.9 0.4 0.82 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4130 RNA_helicase PF00910.22 KKF93497.1 - 0.11 12.9 0.3 0.47 10.9 0.1 2.3 2 0 0 2 2 2 0 RNA helicase MgtE_N PF03448.17 KKF93497.1 - 0.12 12.9 0.4 4.1 8.0 0.1 2.8 2 0 0 2 2 2 0 MgtE intracellular N domain TMP_2 PF06791.13 KKF93500.1 - 0.035 13.8 6.6 0.043 13.5 6.6 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein PMEI PF04043.15 KKF93500.1 - 0.077 13.3 9.9 0.094 13.1 9.9 1.1 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor APG6_N PF17675.1 KKF93500.1 - 0.26 11.8 4.7 0.3 11.6 4.7 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3584 PF12128.8 KKF93500.1 - 0.57 7.6 8.6 0.63 7.5 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Alanine_zipper PF11839.8 KKF93500.1 - 3.7 8.0 38.1 1.6 9.1 20.1 2.2 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Na_Ca_ex PF01699.24 KKF93501.1 - 2.3e-23 82.8 17.6 8.7e-12 45.2 2.4 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1772 PF08592.11 KKF93501.1 - 0.038 14.3 3.1 2.7 8.3 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Cullin PF00888.22 KKF93502.1 - 1.7e-85 287.9 0.7 2.6e-85 287.3 0.0 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KKF93502.1 - 4.2e-24 84.4 0.3 9.8e-24 83.2 0.3 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain PI3_PI4_kinase PF00454.27 KKF93503.1 - 2.8e-50 171.5 0.0 5.9e-50 170.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KKF93503.1 - 4.2e-11 42.4 0.0 1.7e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 FATC domain DUF919 PF06034.11 KKF93503.1 - 3 7.7 5.0 23 4.9 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Nup192 PF11894.8 KKF93504.1 - 0 1273.6 5.3 0 1273.4 5.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Cpn60_TCP1 PF00118.24 KKF93505.1 - 3.1e-149 497.8 16.1 3.5e-149 497.6 16.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.11 KKF93506.1 - 5.6e-23 80.9 0.1 1.3e-22 79.8 0.1 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KKF93506.1 - 4.5e-20 72.4 0.0 8.7e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKF93506.1 - 1.2e-17 63.8 0.0 2.7e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Rieske PF00355.26 KKF93507.1 - 8.4e-12 44.9 0.0 1.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KKF93507.1 - 3.7e-09 36.9 0.2 8e-09 35.9 0.2 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region PQ-loop PF04193.14 KKF93508.1 - 1.6e-25 88.6 3.2 6.7e-12 45.0 1.1 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KKF93508.1 - 0.044 14.6 1.6 0.44 11.4 0.6 2.3 2 0 0 2 2 2 0 ER lumen protein retaining receptor DUF3087 PF11286.8 KKF93508.1 - 0.054 13.0 0.3 0.1 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) SCAMP PF04144.13 KKF93508.1 - 1.4 9.2 11.3 0.46 10.8 4.0 2.3 2 1 0 2 2 2 0 SCAMP family DXP_reductoisom PF02670.16 KKF93509.1 - 0.032 14.9 0.9 0.076 13.7 0.9 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GTP_EFTU PF00009.27 KKF93510.1 - 1.4e-33 116.1 0.0 2.4e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KKF93510.1 - 2e-21 75.9 0.0 3.8e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KKF93510.1 - 2.3e-12 46.8 0.1 1.9e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G C-terminus RF3_C PF16658.5 KKF93510.1 - 3.5e-05 23.6 0.0 0.002 18.0 0.0 2.4 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 KKF93510.1 - 0.0058 16.4 0.0 0.056 13.2 0.0 2.5 1 1 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KKF93510.1 - 0.45 10.9 2.9 5.8 7.4 2.1 2.9 2 1 0 2 2 2 0 Elongation factor Tu domain 2 Cupin_1 PF00190.22 KKF93511.1 - 3.7e-16 59.1 0.2 7.3e-16 58.1 0.2 1.4 1 0 0 1 1 1 1 Cupin SUN PF03856.13 KKF93512.1 - 4.8e-77 258.7 7.1 6.4e-77 258.3 7.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) NACHT PF05729.12 KKF93514.1 - 7.8e-09 35.7 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Patatin PF01734.22 KKF93514.1 - 1.2e-05 25.6 0.7 0.0004 20.6 0.0 2.5 1 1 1 2 2 2 1 Patatin-like phospholipase AAA_19 PF13245.6 KKF93514.1 - 0.0018 18.6 0.0 0.0058 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KKF93514.1 - 0.024 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKF93514.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KKF93514.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Fungal_trans PF04082.18 KKF93515.1 - 1e-08 34.5 0.0 2.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arginase PF00491.21 KKF93516.1 - 1.6e-87 293.6 0.0 1.8e-87 293.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KKF93516.1 - 0.015 15.6 0.1 0.024 14.9 0.1 1.2 1 0 0 1 1 1 0 UPF0489 domain AA_permease PF00324.21 KKF93517.1 - 1e-100 337.6 41.2 1.3e-100 337.3 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKF93517.1 - 5.7e-31 107.8 40.9 7e-31 107.5 40.9 1.1 1 0 0 1 1 1 1 Amino acid permease Transp_cyt_pur PF02133.15 KKF93518.1 - 1.7e-32 112.8 30.6 2.3e-31 109.1 30.6 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pec_lyase_C PF00544.19 KKF93519.1 - 6.6e-15 55.3 2.1 1.7e-13 50.7 2.1 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KKF93519.1 - 3.3e-05 23.8 4.8 0.014 15.2 2.1 2.6 1 1 1 2 2 2 2 Right handed beta helix region adh_short PF00106.25 KKF93520.1 - 2.7e-26 92.2 0.0 1.8e-25 89.6 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF93520.1 - 1.7e-17 63.8 0.0 4.5e-17 62.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF93520.1 - 0.0036 17.2 0.1 0.0063 16.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KKF93520.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SprA-related PF12118.8 KKF93521.1 - 0.0021 17.3 7.0 0.0021 17.3 7.0 2.1 2 0 0 2 2 1 1 SprA-related family Spt20 PF12090.8 KKF93521.1 - 0.012 15.2 40.1 0.1 12.2 14.4 2.1 2 0 0 2 2 2 0 Spt20 family DUF719 PF05334.13 KKF93521.1 - 0.1 12.8 7.0 0.62 10.2 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) ANAPC_CDC26 PF10471.9 KKF93521.1 - 0.12 13.2 32.4 0.63 10.9 10.5 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4770 PF15994.5 KKF93521.1 - 0.23 11.7 13.3 1.1 9.5 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Rxt3 PF08642.10 KKF93521.1 - 1.5 9.6 5.6 5.2 7.8 1.0 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Hydin_ADK PF17213.3 KKF93521.1 - 3 8.1 10.1 3.5 7.9 3.0 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain PKI PF02827.16 KKF93521.1 - 3.7 7.8 10.2 0.62 10.3 0.4 2.5 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor MMR1 PF08505.10 KKF93521.1 - 4.1 7.6 16.7 1.7 8.9 5.1 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Connexin PF00029.19 KKF93521.1 - 6.6 6.4 6.4 6.6 6.4 1.5 2.1 2 0 0 2 2 2 0 Connexin eIF-3_zeta PF05091.12 KKF93521.1 - 9 5.1 16.6 4.1 6.3 2.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DHO_dh PF01180.21 KKF93522.1 - 1.3e-23 83.7 0.0 1.9e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase p450 PF00067.22 KKF93523.1 - 1.6e-43 149.1 4.9 3e-41 141.7 0.8 2.7 2 1 0 2 2 2 2 Cytochrome P450 PPR_2 PF13041.6 KKF93525.1 - 3.9e-17 62.2 0.0 7.3e-07 29.3 0.0 5.5 6 0 0 6 6 6 3 PPR repeat family PPR_1 PF12854.7 KKF93525.1 - 5.4e-12 45.2 0.0 0.00028 20.5 0.0 4.7 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KKF93525.1 - 2.7e-10 40.2 0.0 0.0002 21.4 0.0 2.8 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 KKF93525.1 - 1.2e-08 34.6 0.2 0.015 15.5 0.0 4.5 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 KKF93525.1 - 0.077 12.3 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP cwf18 PF08315.12 KKF93526.1 - 1.6e-41 142.1 7.4 1.6e-41 142.1 7.4 1.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor DUF5386 PF17360.2 KKF93526.1 - 0.1 12.5 0.2 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5386) Pyridoxal_deC PF00282.19 KKF93527.1 - 8.3e-25 87.3 0.0 1.3e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 KKF93527.1 - 0.0027 16.9 0.0 0.0057 15.9 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKF93527.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF2462 PF09495.10 KKF93528.1 - 8.4e-13 48.9 14.0 1.1e-12 48.5 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) COX16 PF14138.6 KKF93529.1 - 2.7e-24 85.5 0.0 3.5e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Upf2 PF04050.14 KKF93530.1 - 0.11 13.2 4.6 0.13 13.0 3.9 1.5 1 1 0 1 1 1 0 Up-frameshift suppressor 2 Metallophos PF00149.28 KKF93531.1 - 8.7e-31 108.0 0.2 1.4e-30 107.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KKF93531.1 - 0.096 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Exo84_C PF16528.5 KKF93532.1 - 1.6e-69 233.8 6.7 1.8e-69 233.7 0.2 2.9 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KKF93532.1 - 7.8e-11 41.9 2.5 7.8e-11 41.9 2.5 2.1 2 0 0 2 2 2 1 Vps51/Vps67 DUF4407 PF14362.6 KKF93532.1 - 0.021 14.2 1.5 0.14 11.5 1.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HMMR_C PF15908.5 KKF93532.1 - 0.095 13.0 3.8 0.048 13.9 1.0 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal TSC22 PF01166.18 KKF93532.1 - 0.11 12.8 4.0 6.1 7.2 0.8 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 KKF93532.1 - 3.3 8.4 7.2 0.66 10.7 0.9 2.8 2 1 1 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 KKF93532.1 - 4.3 7.5 7.8 6.4 6.9 1.8 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MAS20 PF02064.15 KKF93533.1 - 3e-39 134.1 0.6 3e-39 134.1 0.6 1.7 2 1 1 3 3 3 1 MAS20 protein import receptor Chitin_synth_2 PF03142.15 KKF93534.1 - 2.1e-243 808.8 1.4 2.9e-243 808.3 1.4 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KKF93534.1 - 3.7e-78 263.4 0.0 7.1e-78 262.5 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Wyosine_form PF08608.12 KKF93534.1 - 1.7e-22 79.5 0.0 4e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation DEK_C PF08766.11 KKF93534.1 - 6.8e-16 57.9 0.0 2.6e-15 56.1 0.1 2.0 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KKF93534.1 - 1.3e-14 54.1 0.3 4.2e-12 46.0 0.0 2.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Radical_SAM PF04055.21 KKF93534.1 - 3.8e-14 53.4 0.0 9.4e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Glyco_trans_2_3 PF13632.6 KKF93534.1 - 8.3e-11 42.2 4.1 2.3e-10 40.7 4.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Flavodoxin_1 PF00258.25 KKF93534.1 - 1.9e-09 37.8 3.0 4.3e-07 30.2 0.6 4.3 3 1 0 3 3 3 1 Flavodoxin Glyco_tranf_2_3 PF13641.6 KKF93534.1 - 1.9e-06 28.0 0.0 4.8e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KKF93534.1 - 0.0052 16.6 0.0 4.6 7.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 RsgA_GTPase PF03193.16 KKF93534.1 - 0.028 14.3 0.1 0.078 12.9 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KKF93534.1 - 0.032 14.6 0.3 0.17 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KKF93534.1 - 0.048 14.2 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KKF93534.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Chitin_synth_2 PF03142.15 KKF93535.1 - 8.7e-231 767.1 0.1 1.2e-230 766.7 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 KKF93535.1 - 2.4e-16 59.4 0.8 2.1e-15 56.4 1.1 2.2 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KKF93535.1 - 2.1e-15 56.6 0.4 1.4e-10 41.2 0.1 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KKF93535.1 - 2e-13 50.7 1.7 2e-13 50.7 1.7 2.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKF93535.1 - 8.3e-13 48.8 0.0 4.7e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KKF93535.1 - 2.6e-09 35.9 0.0 1.2e-08 33.7 0.0 1.8 1 1 1 2 2 2 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 KKF93535.1 - 9.2e-05 22.3 0.0 0.023 14.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KKF93535.1 - 0.00043 19.8 0.0 0.0024 17.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 BCDHK_Adom3 PF10436.9 KKF93536.1 - 8.9e-46 155.7 0.0 1.3e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KKF93536.1 - 2.8e-11 43.9 0.0 1.1e-09 38.8 0.0 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.16 KKF93536.1 - 0.0072 17.0 0.0 0.028 15.1 0.0 2.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 HATPase_c_3 PF13589.6 KKF93536.1 - 0.054 13.3 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKF93536.1 - 0.16 11.9 0.0 0.46 10.4 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain RIBIOP_C PF04950.12 KKF93537.1 - 9.3e-93 310.8 0.1 9.3e-93 310.8 0.1 2.4 3 0 0 3 3 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KKF93537.1 - 5.3e-28 96.9 0.0 1.8e-27 95.2 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KKF93537.1 - 8.1e-05 22.9 0.0 0.00024 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKF93537.1 - 0.00016 22.2 0.4 0.63 10.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKF93537.1 - 0.0002 21.8 0.0 0.00054 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KKF93537.1 - 0.00085 19.3 0.0 0.0029 17.5 0.0 2.0 1 1 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.23 KKF93537.1 - 0.002 18.2 0.0 0.0085 16.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KKF93537.1 - 0.0023 18.5 0.1 0.01 16.4 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA PF00004.29 KKF93537.1 - 0.0032 17.9 0.0 0.0068 16.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 KKF93537.1 - 0.0086 16.0 0.1 2.6 7.9 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KKF93537.1 - 0.012 15.8 1.3 0.027 14.6 0.0 2.4 2 0 0 2 2 1 0 AAA domain GTP_EFTU PF00009.27 KKF93537.1 - 0.013 15.1 0.0 0.21 11.1 0.0 2.5 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 KKF93537.1 - 0.015 14.9 0.0 0.28 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KKF93537.1 - 0.02 15.2 0.0 0.071 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KKF93537.1 - 0.028 13.6 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KKF93537.1 - 0.038 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KKF93537.1 - 0.043 13.9 0.2 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKF93537.1 - 0.058 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 KKF93537.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ThiF PF00899.21 KKF93538.1 - 2.3e-108 361.2 0.0 1.7e-72 243.7 0.0 2.3 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KKF93538.1 - 7.9e-88 294.6 1.1 1.3e-87 293.9 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KKF93538.1 - 2.5e-29 101.2 0.1 8.6e-29 99.6 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KKF93538.1 - 8e-27 93.8 0.1 1.7e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KKF93538.1 - 4.1e-24 84.5 0.8 1.4e-23 82.9 0.8 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle GST_N_2 PF13409.6 KKF93538.1 - 3.6e-22 78.4 0.0 1.1e-21 76.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKF93538.1 - 7.7e-14 51.5 0.0 2.6e-13 49.8 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KKF93538.1 - 0.0035 17.7 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KKF93538.1 - 0.015 15.9 0.0 0.035 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKF93538.1 - 0.032 14.4 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FKBP_C PF00254.28 KKF93539.1 - 2.2e-23 82.4 0.0 2.8e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RasGEF PF00617.19 KKF93540.1 - 6.1e-49 166.6 0.1 1e-48 165.9 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KKF93540.1 - 3.4e-14 53.0 0.0 1.6e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif ABC2_membrane PF01061.24 KKF93541.1 - 1.8e-84 282.3 67.2 1.6e-43 148.6 18.2 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KKF93541.1 - 3.7e-36 124.7 0.0 4.3e-17 62.9 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KKF93541.1 - 1.2e-32 111.7 10.1 1.7e-26 91.9 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KKF93541.1 - 1.6e-14 54.2 0.1 4.1e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KKF93541.1 - 4e-08 32.8 9.5 4e-08 32.8 9.5 4.1 4 2 0 4 4 4 3 ABC-2 family transporter protein AAA_25 PF13481.6 KKF93541.1 - 6.3e-07 29.2 0.1 0.00022 20.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKF93541.1 - 9e-06 26.2 0.4 0.0011 19.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKF93541.1 - 2e-05 24.6 0.0 0.0038 17.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KKF93541.1 - 0.00013 22.5 0.0 0.0014 19.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_2 PF12679.7 KKF93541.1 - 0.00017 21.0 4.8 0.00017 21.0 4.8 3.5 3 1 0 3 3 3 1 ABC-2 family transporter protein AAA_29 PF13555.6 KKF93541.1 - 0.00053 19.7 0.6 0.049 13.4 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 KKF93541.1 - 0.0007 19.2 0.7 0.1 12.2 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KKF93541.1 - 0.0081 16.3 4.1 0.01 16.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KKF93541.1 - 0.013 15.4 1.7 3 7.7 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.6 KKF93541.1 - 0.016 15.0 0.2 2 8.1 0.1 2.6 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KKF93541.1 - 0.018 15.1 0.0 8 6.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KKF93541.1 - 0.03 14.1 0.6 1.7 8.3 0.4 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KKF93541.1 - 0.064 13.7 1.2 1.3 9.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain SMC_N PF02463.19 KKF93541.1 - 0.071 12.5 0.0 2.6 7.4 0.0 2.8 3 1 1 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKF93541.1 - 0.081 13.2 1.2 2.5 8.4 0.2 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KKF93541.1 - 0.16 12.4 0.2 19 5.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1992 PF09350.10 KKF93542.1 - 3.6e-17 62.3 0.1 1.4e-16 60.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) LysM PF01476.20 KKF93543.1 - 1.3e-15 57.1 0.0 1.4e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 LysM domain Herpes_BLLF1 PF05109.13 KKF93543.1 - 0.038 12.0 6.2 0.04 11.9 6.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) S36_mt PF10937.8 KKF93544.1 - 1.8e-30 106.9 0.3 2.3e-30 106.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Fungal_lectin PF07938.12 KKF93545.1 - 1.3e-45 156.1 0.3 1.5e-45 155.9 0.3 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin RIFIN PF02009.16 KKF93546.1 - 3.2 7.5 13.6 4.1 7.2 13.6 1.1 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 KKF93546.1 - 6.4 5.2 21.1 7.9 4.9 21.1 1.0 1 0 0 1 1 1 0 Macoilin family Defensin_propep PF00879.18 KKF93547.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Defensin propeptide DUF2509 PF10713.9 KKF93547.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) NACHT_N PF17100.5 KKF93548.1 - 1.2e-62 211.6 1.8 4.1e-62 209.9 1.9 1.8 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 KKF93548.1 - 7.9e-59 194.3 34.5 1e-10 42.0 0.1 9.7 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF93548.1 - 1.8e-25 89.0 3.5 9e-05 22.7 0.0 6.5 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF93548.1 - 1.1e-11 44.3 8.6 5.8e-06 25.5 0.4 3.8 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Robl_LC7 PF03259.17 KKF93548.1 - 0.00014 21.6 0.3 11 5.8 0.0 5.1 3 2 2 5 5 5 1 Roadblock/LC7 domain PD40 PF07676.12 KKF93548.1 - 0.00014 21.7 0.0 73 3.5 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1241 PF06840.11 KKF93548.1 - 0.0016 18.1 0.1 0.0034 17.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) DUF3748 PF12566.8 KKF93548.1 - 0.16 11.9 2.7 31 4.6 0.0 4.2 3 1 1 5 5 5 0 Protein of unknown function (DUF3748) Big_7 PF17957.1 KKF93548.1 - 1.2 10.0 16.6 18 6.2 0.5 5.1 3 2 2 5 5 5 0 Bacterial Ig domain DRE2_N PF16803.5 KKF93552.1 - 0.028 14.7 0.1 1.9 8.7 0.0 2.6 3 0 0 3 3 3 0 Fe-S cluster assembly protein DRE2 N-terminus Cdc6_C PF09079.11 KKF93554.1 - 0.18 11.8 0.0 0.43 10.6 0.0 1.6 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain DUF2076 PF09849.9 KKF93557.1 - 1.7e-06 28.3 12.1 2.4e-06 27.8 12.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KKF93557.1 - 2.3e-05 24.4 2.1 3.3e-05 23.9 2.1 1.3 1 0 0 1 1 1 1 CHCH domain Trypan_glycop_C PF10659.9 KKF93557.1 - 0.051 13.9 0.3 0.073 13.5 0.3 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain COX17 PF05051.13 KKF93557.1 - 0.071 13.5 1.0 0.12 12.7 0.1 1.7 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 KKF93557.1 - 0.074 13.1 1.6 0.11 12.5 1.6 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Antimicrobial24 PF16049.5 KKF93557.1 - 0.9 9.6 2.9 1.5 8.8 0.3 2.3 2 0 0 2 2 2 0 Frog antimicrobial peptide DUF3597 PF12200.8 KKF93557.1 - 2.7 8.6 6.2 21 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) UBX PF00789.20 KKF93558.1 - 1.2e-12 47.8 0.0 2.3e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain TauD PF02668.16 KKF93559.1 - 1.7e-64 218.2 0.4 2e-64 218.0 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KKF93560.1 - 3.9e-12 45.8 24.2 8.5e-12 44.7 11.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Ion_trans PF00520.31 KKF93562.1 - 7.1e-09 35.3 26.4 3.9e-08 32.8 26.4 2.0 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KKF93562.1 - 7.2e-05 21.6 13.3 0.0037 16.0 4.5 2.3 1 1 1 2 2 2 2 Polycystin cation channel Glyco_hydro_76 PF03663.14 KKF93564.1 - 6.6e-134 447.0 3.7 9.2e-134 446.6 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KKF93564.1 - 0.00042 19.5 3.9 0.021 13.9 0.2 3.0 2 1 2 4 4 4 2 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 KKF93564.1 - 0.0065 15.8 0.1 3 7.0 0.0 2.2 2 0 0 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_127 PF07944.12 KKF93564.1 - 0.062 11.8 0.2 0.28 9.6 0.0 2.0 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Patatin PF01734.22 KKF93566.1 - 8.2e-13 49.0 0.0 1.4e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Aldo_ket_red PF00248.21 KKF93567.1 - 2.5e-40 138.5 0.0 1.6e-34 119.5 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Tox-GHH PF15636.6 KKF93567.1 - 0.1 12.6 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin zf-H2C2_2 PF13465.6 KKF93568.1 - 2.3e-07 30.9 19.4 0.00016 22.0 4.5 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KKF93568.1 - 3.3e-07 30.4 17.2 0.0028 18.0 3.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKF93568.1 - 0.00082 20.0 14.5 0.15 12.9 3.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KKF93568.1 - 0.029 15.0 1.9 0.029 15.0 1.9 1.9 2 0 0 2 2 2 0 FOXP coiled-coil domain Serglycin PF04360.12 KKF93568.1 - 0.11 12.4 2.1 0.25 11.3 2.1 1.6 1 0 0 1 1 1 0 Serglycin zf-C2H2_6 PF13912.6 KKF93568.1 - 0.49 10.4 4.9 3.3 7.8 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KKF93568.1 - 3.9 7.3 11.9 4.3 7.2 0.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Peptidase_C1_2 PF03051.15 KKF93570.1 - 4.2e-147 490.5 0.0 5.5e-147 490.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KKF93570.1 - 1.3e-06 28.6 0.4 0.0087 16.2 0.4 2.5 2 0 0 2 2 2 2 Papain family cysteine protease Zip PF02535.22 KKF93571.1 - 4.3 6.5 9.4 6.4 5.9 9.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KKF93571.1 - 8.1 5.1 5.6 13 4.5 5.6 1.3 1 0 0 1 1 1 0 Presenilin zf-C3H1 PF10650.9 KKF93572.1 - 0.26 11.0 3.2 0.45 10.3 3.2 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain DivIC PF04977.15 KKF93572.1 - 0.54 10.1 8.1 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 KKF93572.1 - 1.1 10.0 9.9 0.29 11.8 1.9 2.7 2 0 0 2 2 2 0 SlyX LsmAD PF06741.13 KKF93572.1 - 9.4 6.9 7.2 2.7 8.6 3.2 2.3 2 0 0 2 2 2 0 LsmAD domain Myosin_head PF00063.21 KKF93573.1 - 1.3e-263 876.3 0.0 3.8e-263 874.7 0.0 1.9 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KKF93573.1 - 2.5e-12 46.4 0.1 6.3e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KKF93573.1 - 3e-08 32.0 34.8 3e-08 32.0 34.8 6.4 2 2 3 5 5 5 3 Myosin tail AAA_22 PF13401.6 KKF93573.1 - 0.18 12.1 0.0 0.18 12.1 0.0 4.9 5 0 0 5 5 5 0 AAA domain YvrJ PF12841.7 KKF93573.1 - 0.2 11.2 5.7 0.74 9.4 0.2 3.6 3 0 0 3 3 3 0 YvrJ protein family Pkinase PF00069.25 KKF93576.1 - 2.5e-19 69.7 0.0 3.6e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KKF93576.1 - 4.5e-08 32.3 0.0 1.1e-07 31.0 0.0 1.7 3 0 0 3 3 3 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KKF93576.1 - 0.00013 21.3 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LNS2 PF08235.13 KKF93576.1 - 0.18 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) TFIIA PF03153.13 KKF93577.1 - 0.0017 18.5 12.7 0.0017 18.5 12.7 4.2 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit HET PF06985.11 KKF93578.1 - 6.1e-18 65.6 0.6 6.1e-18 65.6 0.6 4.1 3 2 0 3 3 3 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KKF93579.1 - 2.1e-09 37.9 2.8 3.4e-08 34.0 0.5 2.3 2 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) BRO1 PF03097.18 KKF93579.1 - 0.066 12.0 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 BRO1-like domain SNF2_N PF00176.23 KKF93580.1 - 9.2e-74 248.2 0.2 2e-73 247.1 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KKF93580.1 - 4.5e-23 81.1 0.4 1.2e-22 79.8 0.4 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 KKF93580.1 - 1.6e-21 76.7 0.4 1e-18 67.6 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.6 KKF93580.1 - 7.5e-15 55.3 0.4 7.5e-15 55.3 0.4 4.2 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KKF93580.1 - 4.8e-13 48.6 0.9 1.1e-12 47.4 0.9 1.7 1 0 0 1 1 1 1 QLQ HSA PF07529.13 KKF93580.1 - 5.5e-13 49.0 8.7 5.5e-13 49.0 8.7 4.6 4 0 0 4 4 4 1 HSA ResIII PF04851.15 KKF93580.1 - 1.3e-11 44.8 1.4 3.6e-11 43.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RBR PF17208.3 KKF93580.1 - 2.3e-05 25.0 1.6 2.3e-05 25.0 1.6 2.2 2 0 0 2 2 2 1 RNA binding Region MSA-2c PF12238.8 KKF93580.1 - 5.1 7.0 8.4 0.26 11.3 0.1 2.8 3 0 0 3 3 3 0 Merozoite surface antigen 2c DUF2841 PF11001.8 KKF93581.1 - 4.4e-40 136.6 1.2 8.7e-40 135.6 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) RPA_C PF08784.11 KKF93582.1 - 0.095 13.4 2.1 0.34 11.6 1.4 2.3 2 0 0 2 2 2 0 Replication protein A C terminal RasGEF PF00617.19 KKF93583.1 - 7.1e-46 156.6 0.8 1.1e-45 156.0 0.8 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KKF93583.1 - 1.1e-12 48.1 0.2 3.1e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 RasGEF N-terminal motif LSM PF01423.22 KKF93584.1 - 1e-15 57.2 0.0 2e-15 56.2 0.0 1.5 2 0 0 2 2 2 1 LSM domain Hfq PF17209.3 KKF93584.1 - 0.039 13.6 0.1 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 Hfq protein ATE_C PF04377.15 KKF93585.1 - 7.4e-46 156.1 0.6 1.2e-45 155.4 0.6 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Acetyltransf_6 PF13480.7 KKF93585.1 - 0.015 15.4 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNA_pol_Rpb4 PF03874.16 KKF93586.1 - 2.6e-20 73.0 0.0 8.6e-20 71.3 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb4 CotJB PF12652.7 KKF93586.1 - 0.062 13.5 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 CotJB protein PseudoU_synth_1 PF01416.20 KKF93587.1 - 8e-36 122.8 0.0 6.8e-35 119.8 0.0 2.2 2 0 0 2 2 2 1 tRNA pseudouridine synthase PIG-H PF10181.9 KKF93588.1 - 5.2e-20 71.1 0.0 7.4e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF359 PF04019.12 KKF93588.1 - 0.08 12.6 0.1 0.19 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF359) DUF3984 PF13136.6 KKF93589.1 - 3.5e-15 56.2 5.5 3.6e-14 52.9 5.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) VbhA PF18495.1 KKF93589.1 - 0.07 13.0 0.1 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Antitoxin VbhA IKI3 PF04762.12 KKF93590.1 - 2.7e-281 935.8 0.0 3.2e-281 935.5 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 KKF93590.1 - 1.9e-05 24.9 3.8 6.1 7.2 0.5 5.8 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain bPH_4 PF06713.11 KKF93590.1 - 0.041 14.0 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 Bacterial PH domain TPR_2 PF07719.17 KKF93590.1 - 0.26 11.5 7.9 1.6 9.0 2.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKF93590.1 - 1.6 8.7 5.3 0.87 9.5 1.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKF93590.1 - 2.6 8.3 5.6 2.4 8.4 0.3 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Ras PF00071.22 KKF93592.1 - 3.2e-56 189.4 0.0 3.6e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF93592.1 - 1.3e-21 77.1 0.0 1.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF93592.1 - 1.1e-06 28.2 0.0 2e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKF93592.1 - 0.00035 20.2 0.0 0.00091 18.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKF93592.1 - 0.01 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KKF93592.1 - 0.045 12.9 0.1 0.45 9.6 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 KKF93592.1 - 0.12 11.6 0.0 0.16 11.3 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Aa_trans PF01490.18 KKF93593.1 - 8.4e-74 248.7 26.2 1e-73 248.4 26.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Asp PF00026.23 KKF93594.1 - 1e-64 219.0 6.1 1e-64 219.0 6.1 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKF93594.1 - 1.5e-11 44.9 12.5 6.5e-10 39.5 7.8 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKF93594.1 - 0.063 13.9 4.3 1.8 9.2 0.1 3.4 3 2 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.6 KKF93594.1 - 0.14 12.7 2.0 1.4 9.5 0.0 3.2 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease PPTA PF01239.22 KKF93595.1 - 0.0001 21.9 22.2 0.0015 18.2 1.0 4.3 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.14 KKF93596.1 - 6.5e-55 185.3 0.9 6.5e-55 185.3 0.9 2.2 3 0 0 3 3 3 1 CHD5-like protein 7TM_GPCR_Srt PF10321.9 KKF93596.1 - 0.023 13.7 0.5 0.04 12.9 0.5 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt LXG PF04740.12 KKF93596.1 - 0.17 11.6 1.2 0.82 9.3 0.1 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily GRAB PF10375.9 KKF93597.1 - 9e-05 22.2 1.6 0.00015 21.5 0.1 2.1 2 0 0 2 2 2 1 GRIP-related Arf-binding domain Spc7 PF08317.11 KKF93597.1 - 0.0014 17.6 28.7 0.0014 17.6 28.7 2.7 1 1 1 2 2 2 2 Spc7 kinetochore protein GRIP PF01465.20 KKF93597.1 - 0.015 15.2 0.1 0.035 14.0 0.1 1.7 1 0 0 1 1 1 0 GRIP domain DUF3584 PF12128.8 KKF93597.1 - 0.15 9.5 45.0 0.44 8.0 29.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 KKF93597.1 - 0.18 11.2 48.3 0.11 11.9 31.9 2.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 NPV_P10 PF05531.12 KKF93597.1 - 0.26 11.7 15.7 1.4 9.5 2.3 4.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FPP PF05911.11 KKF93597.1 - 0.3 9.2 42.7 0.084 11.0 26.2 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil BLOC1_2 PF10046.9 KKF93597.1 - 0.33 11.3 29.8 0.15 12.4 10.6 4.4 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.10 KKF93597.1 - 0.99 9.3 4.9 10 6.0 0.2 4.1 3 1 1 4 4 4 0 DASH complex subunit Dam1 FAM184 PF15665.5 KKF93597.1 - 1 9.1 46.7 0.16 11.8 9.4 3.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Tweety PF04906.13 KKF93597.1 - 1.1 7.8 9.5 0.34 9.5 1.7 2.4 1 1 0 2 2 2 0 Tweety TPR_MLP1_2 PF07926.12 KKF93597.1 - 1.2 9.2 57.3 0.55 10.3 9.7 4.3 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 KKF93597.1 - 1.7 8.7 47.9 0.88 9.6 28.6 3.8 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF4618 PF15397.6 KKF93597.1 - 1.7 8.0 38.1 0.22 10.9 14.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) GAS PF13851.6 KKF93597.1 - 2.5 7.4 50.0 0.46 9.8 11.4 3.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4988 PF16378.5 KKF93597.1 - 2.6 7.7 7.9 2.6 7.7 0.2 3.6 2 1 0 3 3 3 0 Domain of unknown function Filament PF00038.21 KKF93597.1 - 2.8 7.5 47.3 0.44 10.1 28.3 2.3 1 1 1 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 KKF93597.1 - 7.9 6.5 24.4 0.3 11.1 3.6 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) RRM_1 PF00076.22 KKF93598.1 - 2.1e-14 53.1 0.0 4.7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN PF06003.12 KKF93599.1 - 0.053 12.8 0.3 0.053 12.8 0.3 1.5 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) VHS PF00790.19 KKF93600.1 - 4.4e-07 29.8 0.0 1.7e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 VHS domain CTD_bind PF04818.13 KKF93600.1 - 2.3e-06 28.3 0.1 1.9e-05 25.4 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 KKF93600.1 - 0.00021 21.7 2.3 0.00074 19.9 1.1 2.3 1 1 1 2 2 2 1 Subunit of cleavage factor IA Pcf11 zf-ISL3 PF14690.6 KKF93600.1 - 0.17 12.6 1.7 0.44 11.3 1.7 1.7 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_4 PF13894.6 KKF93600.1 - 0.5 11.4 2.9 2.4 9.2 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Prok-RING_1 PF14446.6 KKF93600.1 - 6.6 6.7 7.1 16 5.5 0.2 3.3 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 AcetylCoA_hydro PF02550.15 KKF93601.1 - 4e-46 157.5 0.0 6.9e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KKF93601.1 - 1.9e-43 148.0 0.0 3.5e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Acetyltransf_1 PF00583.25 KKF93602.1 - 3.3e-13 49.9 0.0 4.4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKF93602.1 - 3.2e-10 40.0 0.0 3.8e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKF93602.1 - 1.3e-09 37.9 0.1 1.6e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KKF93602.1 - 5.4e-09 36.3 0.0 7.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KKF93602.1 - 1.3e-06 28.2 0.0 1.5e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKF93602.1 - 1e-05 26.3 0.0 1.3e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKF93602.1 - 6.7e-05 23.0 0.0 8.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKF93602.1 - 0.0016 18.5 0.1 0.0025 17.9 0.1 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 KKF93602.1 - 0.0048 16.7 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KKF93602.1 - 0.033 13.8 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_15 PF17013.5 KKF93602.1 - 0.053 13.0 0.0 0.069 12.6 0.0 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase HMG_box PF00505.19 KKF93603.1 - 1.5e-12 47.8 0.1 5.3e-12 46.0 0.4 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 KKF93603.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box HMG_box_2 PF09011.10 KKF93603.1 - 0.013 16.0 0.5 0.026 15.1 0.5 1.5 1 0 0 1 1 1 0 HMG-box domain Amidase PF01425.21 KKF93604.1 - 5.2e-64 216.9 0.1 1.4e-63 215.5 0.0 1.5 2 0 0 2 2 2 1 Amidase Alk_phosphatase PF00245.20 KKF93605.1 - 3.5e-65 220.6 0.1 9.1e-65 219.2 0.1 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 KKF93605.1 - 1.1e-08 35.2 0.0 2.7e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKF93605.1 - 1.2e-05 24.9 0.0 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KKF93605.1 - 0.0022 16.7 0.2 0.0033 16.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KKF93605.1 - 0.015 14.6 0.1 0.047 13.1 0.0 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily PglZ PF08665.12 KKF93605.1 - 0.17 12.0 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 PglZ domain RIF5_SNase_1 PF18187.1 KKF93605.1 - 0.21 11.3 0.0 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 TbRIF5 SNase domain 1 DUF229 PF02995.17 KKF93606.1 - 0.0037 15.9 0.1 0.0052 15.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) PglZ PF08665.12 KKF93606.1 - 0.077 13.1 0.4 0.11 12.5 0.4 1.3 1 0 0 1 1 1 0 PglZ domain Alk_phosphatase PF00245.20 KKF93606.1 - 0.43 9.5 10.0 3.1 6.6 0.0 3.2 2 1 2 4 4 4 0 Alkaline phosphatase FMN_bind_2 PF04299.12 KKF93607.1 - 9.1e-35 119.8 0.0 4.9e-34 117.5 0.0 2.0 1 1 0 1 1 1 1 Putative FMN-binding domain Aminotran_3 PF00202.21 KKF93607.1 - 1.1e-34 119.9 0.0 9.1e-19 67.4 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 KKF93607.1 - 0.0025 17.7 0.2 0.0057 16.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain BATS PF06968.13 KKF93608.1 - 6.5e-24 83.9 0.0 1.7e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KKF93608.1 - 1.4e-14 54.8 0.0 3.3e-14 53.6 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Alk_phosphatase PF00245.20 KKF93609.1 - 8.8e-06 24.9 0.4 5e-05 22.4 0.4 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Glyco_transf_54 PF04666.13 KKF93609.1 - 0.16 10.8 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Pkinase_fungal PF17667.1 KKF93610.1 - 5e-13 48.6 1.4 6.2e-13 48.3 1.4 1.1 1 0 0 1 1 1 1 Fungal protein kinase PMT PF02366.18 KKF93611.1 - 3.8e-82 275.6 17.8 8e-82 274.5 17.8 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KKF93611.1 - 3e-65 219.6 9.3 3e-65 219.6 9.3 3.0 3 1 1 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KKF93611.1 - 1.5e-20 73.9 0.5 4.8e-20 72.2 0.4 1.8 1 1 1 2 2 2 2 MIR domain CAP59_mtransfer PF11735.8 KKF93612.1 - 8.1e-40 137.0 0.0 1.1e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Porph_ging PF09697.10 KKF93613.1 - 0.17 12.5 6.5 0.68 10.5 6.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (Porph_ging) CDC45 PF02724.14 KKF93613.1 - 5.6 5.1 13.1 6.9 4.8 13.1 1.0 1 0 0 1 1 1 0 CDC45-like protein zf-H2C2_5 PF13909.6 KKF93614.1 - 0.0007 19.3 9.4 0.00093 18.9 3.9 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain CSN5_C PF18323.1 KKF93614.1 - 0.04 14.8 0.1 0.13 13.2 0.0 1.9 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain ResIII PF04851.15 KKF93615.1 - 2.2e-23 83.1 0.0 5.1e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKF93615.1 - 3.8e-20 72.3 0.1 9.2e-20 71.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKF93615.1 - 4.2e-18 65.7 0.2 1.6e-17 63.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KKF93615.1 - 0.00035 20.3 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KKF93615.1 - 0.0068 16.7 0.0 0.045 14.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain IHABP4_N PF16174.5 KKF93615.1 - 1.1 9.8 11.0 0.039 14.6 1.0 2.8 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal TAP_C PF03943.13 KKF93616.1 - 1.1e-11 44.1 0.1 4e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.7 KKF93616.1 - 9.1e-05 22.8 2.1 0.0015 18.9 1.6 3.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 KKF93616.1 - 0.00024 21.7 0.0 0.00081 19.9 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 KKF93616.1 - 0.0019 18.0 0.4 0.011 15.5 0.1 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 KKF93616.1 - 0.075 13.6 2.5 5.8 7.9 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat TMEM154 PF15102.6 KKF93617.1 - 1.8e-05 24.7 0.9 4.4e-05 23.4 0.9 1.7 1 0 0 1 1 1 1 TMEM154 protein family Kelch_4 PF13418.6 KKF93617.1 - 0.0018 18.2 9.5 0.089 12.8 0.3 5.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KKF93617.1 - 0.002 18.4 5.8 0.23 11.8 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KKF93617.1 - 0.89 9.2 8.1 0.5 10.0 0.1 4.1 4 1 0 4 4 4 0 Kelch motif Apt1 PF10351.9 KKF93617.1 - 1 8.1 4.4 1.7 7.4 4.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KKF93617.1 - 1.4 7.4 6.2 1.9 7.0 6.2 1.2 1 0 0 1 1 1 0 Macoilin family Apq12 PF12716.7 KKF93618.1 - 2.9e-09 36.7 12.1 2.9e-09 36.7 12.1 1.6 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.17 KKF93619.1 - 1.6e-72 244.2 0.1 7.1e-72 242.1 0.1 1.8 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KKF93619.1 - 0.0019 18.2 0.0 0.006 16.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain CLP1_P PF16575.5 KKF93619.1 - 0.0027 17.5 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 KKF93619.1 - 0.0032 17.2 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKF93619.1 - 0.0037 17.4 0.0 0.0071 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KKF93619.1 - 0.0039 17.2 0.0 0.0045 17.1 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 KKF93619.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ArsA_ATPase PF02374.15 KKF93619.1 - 0.016 14.4 0.0 0.045 12.9 0.0 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase RsgA_GTPase PF03193.16 KKF93619.1 - 0.017 15.0 0.1 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 KKF93619.1 - 0.024 15.2 0.0 0.055 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKF93619.1 - 0.028 14.8 0.1 0.43 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KKF93619.1 - 0.047 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KKF93619.1 - 0.054 13.8 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKF93619.1 - 0.055 14.0 0.0 0.16 12.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.7 KKF93619.1 - 0.067 12.1 0.0 0.34 9.8 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain GTP_EFTU PF00009.27 KKF93619.1 - 0.099 12.2 0.0 7.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKF93619.1 - 0.13 12.3 0.0 0.43 10.7 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase S-AdoMet_synt_C PF02773.16 KKF93620.1 - 4.8e-66 221.0 0.3 8.1e-66 220.2 0.1 1.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KKF93620.1 - 9.7e-45 151.7 0.0 1.8e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KKF93620.1 - 4.6e-44 149.1 0.4 1.4e-43 147.6 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Egh16-like PF11327.8 KKF93621.1 - 6.1e-49 166.9 10.8 1.2e-48 165.9 10.8 1.5 1 0 0 1 1 1 1 Egh16-like virulence factor MSA-2c PF12238.8 KKF93621.1 - 0.4 10.7 1.7 0.59 10.1 1.7 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Zip PF02535.22 KKF93622.1 - 8.9e-58 196.1 4.5 1.5e-57 195.3 4.5 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter WD40 PF00400.32 KKF93623.1 - 9.5e-17 61.1 12.5 9.2e-06 26.3 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 KKF93623.1 - 1.4e-15 57.6 0.1 2.3e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KKF93623.1 - 4.4e-07 28.9 0.5 0.005 15.5 0.1 3.0 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Sec8_exocyst PF04048.14 KKF93624.1 - 1.8e-46 157.6 0.7 5.9e-46 155.9 0.3 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KKF93624.1 - 0.00017 21.0 0.8 0.00044 19.6 0.8 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex RIG-I_C PF18119.1 KKF93624.1 - 0.022 14.8 2.1 0.079 13.0 2.1 1.9 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain TFIIA PF03153.13 KKF93624.1 - 7 6.5 17.1 14 5.6 17.1 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0220 PF05255.11 KKF93625.1 - 6.8e-63 211.1 4.1 7.6e-63 211.0 4.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DNA_pol_A_exo1 PF01612.20 KKF93626.1 - 8.3e-11 41.9 0.1 2.1e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 3'-5' exonuclease LSM PF01423.22 KKF93627.1 - 1.6e-18 66.1 0.1 4.1e-18 64.8 0.1 1.6 1 1 0 1 1 1 1 LSM domain RNA_pol_L_2 PF13656.6 KKF93628.1 - 9.4e-23 79.8 0.1 1.1e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KKF93628.1 - 3.8e-05 23.0 0.0 0.00019 20.8 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SIR2_2 PF13289.6 KKF93628.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 SIR2-like domain Asparaginase PF00710.20 KKF93629.1 - 3.7e-26 91.9 0.0 5.9e-22 78.2 0.0 2.4 1 1 1 2 2 2 2 Asparaginase, N-terminal Asparaginase_C PF17763.1 KKF93629.1 - 6.8e-25 87.5 0.0 1.5e-24 86.4 0.0 1.6 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KKF93629.1 - 5.3e-12 46.2 5.1 4.5e-07 30.4 1.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKF93629.1 - 6.6e-06 26.1 0.8 0.18 12.5 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KKF93629.1 - 1.6e-05 25.4 0.7 0.04 14.5 0.3 3.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KKF93629.1 - 0.00049 20.4 1.4 0.28 11.7 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KKF93629.1 - 0.0033 17.7 1.5 0.017 15.4 0.7 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) WD40 PF00400.32 KKF93630.1 - 1.6e-12 47.7 3.0 0.00025 21.8 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Zn_clus PF00172.18 KKF93630.1 - 5.6e-07 29.6 8.4 9.2e-07 28.9 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC4_WD40 PF12894.7 KKF93630.1 - 5.9e-07 29.7 0.1 0.25 11.6 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain UCH_1 PF13423.6 KKF93631.1 - 2.9e-21 76.4 0.0 1.1e-19 71.2 0.0 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.21 KKF93632.1 - 4.1e-23 81.4 0.0 7.1e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KKF93632.1 - 3.8e-05 23.9 0.0 7.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Fes1 PF08609.10 KKF93633.1 - 1.2e-25 90.2 2.8 4.2e-25 88.5 2.2 2.2 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 KKF93633.1 - 3.1e-08 33.9 0.0 4.7e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.23 KKF93633.1 - 4.6e-08 32.8 0.1 0.017 15.1 0.0 3.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KKF93633.1 - 1.5e-07 31.0 0.1 0.022 15.0 0.0 3.1 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 KKF93633.1 - 3.3e-05 24.3 0.3 0.00024 21.5 0.1 2.5 2 1 0 2 2 2 1 HEAT-like repeat Proteasom_PSMB PF10508.9 KKF93633.1 - 0.04 12.4 0.0 0.048 12.2 0.0 1.3 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.8 KKF93633.1 - 0.072 13.2 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 KKF93633.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Actin PF00022.19 KKF93634.1 - 7.2e-150 499.1 0.0 2.6e-149 497.3 0.0 1.7 1 1 0 1 1 1 1 Actin WD40 PF00400.32 KKF93635.1 - 5.7e-15 55.5 16.1 0.0042 17.9 0.4 9.2 9 1 0 9 9 9 6 WD domain, G-beta repeat RVT_1 PF00078.27 KKF93636.1 - 4.8e-32 111.3 0.0 1.6e-31 109.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KKF93636.1 - 2.9e-13 50.2 0.1 8.4e-13 48.7 0.1 1.9 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.6 KKF93636.1 - 4.3e-05 23.3 0.1 0.00087 19.1 0.0 3.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Flu_PA PF00603.17 KKF93636.1 - 0.007 14.6 0.1 0.011 14.0 0.1 1.1 1 0 0 1 1 1 1 Influenza RNA-dependent RNA polymerase subunit PA RVT_3 PF13456.6 KKF93636.1 - 0.035 13.9 1.5 0.092 12.6 0.3 2.5 2 0 0 2 2 2 0 Reverse transcriptase-like EBP PF05241.12 KKF93637.1 - 2.1e-49 167.4 8.7 2.7e-49 167.1 8.7 1.1 1 0 0 1 1 1 1 Emopamil binding protein TrbC PF04956.13 KKF93637.1 - 0.041 14.1 0.3 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 TrbC/VIRB2 family DUF4293 PF14126.6 KKF93637.1 - 0.075 13.3 4.1 0.21 11.9 4.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Fungal_trans PF04082.18 KKF93638.1 - 7.8e-16 57.9 0.0 1.2e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4306 PF14154.6 KKF93638.1 - 0.029 14.5 0.1 0.052 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Fis1_TPR_C PF14853.6 KKF93639.1 - 9.9e-25 86.4 0.8 1.6e-24 85.7 0.8 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KKF93639.1 - 3.1e-18 65.1 0.1 5.5e-18 64.3 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KKF93639.1 - 7.3e-05 22.6 1.3 0.00016 21.6 1.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKF93639.1 - 0.0019 18.7 0.1 0.0051 17.4 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKF93639.1 - 0.0034 17.2 1.8 0.0062 16.3 1.8 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKF93639.1 - 0.0046 16.9 1.7 0.029 14.4 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat COPI_C PF06957.11 KKF93639.1 - 0.012 14.4 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus TPR_14 PF13428.6 KKF93639.1 - 0.049 14.5 0.3 0.15 13.0 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF93639.1 - 0.065 13.5 0.1 0.16 12.2 0.1 1.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KKF93639.1 - 0.079 13.6 0.2 0.14 12.8 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.11 KKF93640.1 - 3.2e-39 133.4 4.7 2.3e-37 127.4 0.1 2.2 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 Laminin_II PF06009.12 KKF93640.1 - 0.0023 18.0 6.1 0.0054 16.7 6.0 1.7 1 1 0 1 1 1 1 Laminin Domain II V_ATPase_I PF01496.19 KKF93640.1 - 0.0039 15.2 2.4 0.004 15.2 2.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Cid2 PF09774.9 KKF93640.1 - 0.023 15.1 2.4 0.023 15.1 2.4 1.9 2 0 0 2 2 2 0 Caffeine-induced death protein 2 DUF3138 PF11336.8 KKF93640.1 - 0.024 13.3 3.5 0.029 13.0 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FlaC_arch PF05377.11 KKF93640.1 - 0.039 14.3 2.4 0.069 13.5 0.6 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Nsp1_C PF05064.13 KKF93640.1 - 0.082 12.7 2.5 1.8 8.4 0.6 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region EF-hand_14 PF17959.1 KKF93640.1 - 0.12 12.7 1.8 0.29 11.5 1.7 1.8 1 1 0 1 1 1 0 EF-hand domain BLOC1_2 PF10046.9 KKF93640.1 - 0.17 12.2 6.5 0.12 12.7 1.6 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 KKF93640.1 - 0.19 12.5 2.9 0.3 11.8 2.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Prefoldin_2 PF01920.20 KKF93640.1 - 0.24 11.3 6.0 0.83 9.6 1.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF724 PF05266.14 KKF93640.1 - 0.34 10.7 5.8 0.49 10.2 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 KKF93640.1 - 1.5 9.5 8.8 6.8 7.4 1.3 2.5 1 1 1 2 2 2 0 SlyX DUF4164 PF13747.6 KKF93640.1 - 2.2 8.6 13.4 1.3 9.3 9.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) CLZ PF16526.5 KKF93640.1 - 3.3 8.1 9.9 2 8.9 1.9 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Hsk3 PF08227.11 KKF93640.1 - 3.6 8.0 11.5 3.2 8.2 0.5 2.7 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like APG6_N PF17675.1 KKF93640.1 - 4.5 7.8 13.3 9.2 6.8 12.9 1.6 1 1 1 2 2 2 0 Apg6 coiled-coil region TatD_DNase PF01026.21 KKF93641.1 - 1.6e-29 103.1 0.0 2.6e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Pyridox_oxase_2 PF12766.7 KKF93643.1 - 3.2e-19 69.4 0.0 5.1e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DJ-1_PfpI PF01965.24 KKF93645.1 - 1e-14 54.7 0.1 1.6e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KKF93645.1 - 9.7e-05 22.1 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like Cyclin_N PF00134.23 KKF93645.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain ORC4_C PF14629.6 KKF93646.1 - 1.3e-49 168.6 0.0 2.1e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus Mito_carr PF00153.27 KKF93646.1 - 1.4e-35 121.1 2.2 7.8e-18 64.2 0.1 3.2 3 0 0 3 3 3 2 Mitochondrial carrier protein AAA_16 PF13191.6 KKF93646.1 - 1.7e-12 48.0 0.1 7e-12 46.1 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain Ribosomal_L23 PF00276.20 KKF93646.1 - 6.7e-10 39.2 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 PHD PF00628.29 KKF93646.1 - 1.2e-08 34.7 10.0 1.4e-08 34.4 8.6 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KKF93646.1 - 9.7e-08 31.4 2.3 1.8e-07 30.6 2.3 1.5 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.6 KKF93646.1 - 1e-07 32.3 0.0 2.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKF93646.1 - 3.8e-07 30.6 0.0 8.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KKF93646.1 - 2.3e-05 23.8 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_30 PF13604.6 KKF93646.1 - 4e-05 23.4 0.1 9.1e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KKF93646.1 - 5e-05 23.3 0.0 0.00031 20.7 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KKF93646.1 - 0.0001 22.7 0.0 0.00025 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KKF93646.1 - 0.00054 19.2 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KKF93646.1 - 0.0019 18.1 0.0 0.0048 16.9 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KKF93646.1 - 0.0049 16.9 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KKF93646.1 - 0.011 15.0 0.7 0.034 13.3 0.2 1.9 2 0 0 2 2 2 0 NB-ARC domain C1_2 PF03107.16 KKF93646.1 - 0.011 16.0 2.2 0.026 14.8 2.2 1.6 1 0 0 1 1 1 0 C1 domain AAA_29 PF13555.6 KKF93646.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KKF93646.1 - 0.029 13.8 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TniB PF05621.11 KKF93646.1 - 0.033 13.6 0.0 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein ORC2 PF04084.14 KKF93646.1 - 0.038 12.9 0.8 0.64 8.9 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 2 TrwB_AAD_bind PF10412.9 KKF93646.1 - 0.038 12.9 0.1 0.064 12.2 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 KKF93646.1 - 0.04 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KKF93646.1 - 0.05 13.0 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 KKF93646.1 - 0.051 13.4 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KKF93646.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region zf-RRPl_C4 PF17026.5 KKF93646.1 - 0.068 13.3 2.3 0.16 12.1 2.3 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-PHD-like PF15446.6 KKF93646.1 - 0.073 12.7 2.5 0.16 11.6 2.5 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KKF93646.1 - 0.09 12.7 5.7 0.017 15.0 1.7 1.8 2 0 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ATP-synt_ab PF00006.25 KKF93646.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FYVE_2 PF02318.16 KKF93646.1 - 0.14 12.4 0.8 0.3 11.3 0.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Zf_RING PF16744.5 KKF93646.1 - 0.18 11.9 3.8 0.49 10.5 3.8 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger AAA_18 PF13238.6 KKF93646.1 - 0.18 12.3 0.0 0.52 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 KKF93646.1 - 0.23 11.4 6.7 0.45 10.5 6.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Prok-RING_1 PF14446.6 KKF93646.1 - 0.68 9.9 10.9 0.045 13.7 5.4 1.9 2 0 0 2 2 1 0 Prokaryotic RING finger family 1 Retrotran_gag_2 PF14223.6 KKF93648.1 - 1.2e-06 28.2 0.9 3.1e-06 26.9 0.9 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_6 PF15288.6 KKF93648.1 - 0.00063 19.5 1.9 0.0013 18.6 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KKF93648.1 - 0.00072 19.5 2.3 0.0012 18.8 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 KKF93648.1 - 0.025 15.0 0.2 0.064 13.6 0.2 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G NB-ARC PF00931.22 KKF93649.1 - 8.4e-14 51.4 0.2 1.3e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 NB-ARC domain Patatin PF01734.22 KKF93649.1 - 5.9e-08 33.1 0.0 1.5e-05 25.2 0.0 2.4 1 1 0 2 2 2 2 Patatin-like phospholipase NACHT PF05729.12 KKF93649.1 - 0.00048 20.1 0.0 0.00095 19.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KKF93649.1 - 0.002 18.4 0.0 0.0066 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKF93649.1 - 0.0052 17.2 0.2 0.04 14.3 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain DUF3088 PF11287.8 KKF93649.1 - 0.033 14.0 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) CSN8_PSD8_EIF3K PF10075.9 KKF93650.1 - 8.2e-18 64.8 0.0 1.6e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Glyco_hydr_30_2 PF14587.6 KKF93651.1 - 2.7e-20 73.3 3.8 4.2e-20 72.7 3.8 1.3 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Goodbye PF17109.5 KKF93652.1 - 1.2e-22 80.6 1.7 1.6e-22 80.2 0.1 2.1 2 0 0 2 2 1 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 KKF93652.1 - 6.4e-09 36.4 1.5 4.6e-08 33.6 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain TPR_12 PF13424.6 KKF93652.1 - 2.3e-08 34.2 9.1 0.01 16.1 0.3 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKF93652.1 - 4.2e-06 27.0 14.3 0.019 15.6 0.4 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat NACHT PF05729.12 KKF93652.1 - 1.5e-05 25.0 0.0 6.4e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.6 KKF93652.1 - 2e-05 24.3 5.4 0.71 10.0 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKF93652.1 - 3e-05 23.7 12.9 0.00091 19.0 1.3 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKF93652.1 - 9.3e-05 22.3 10.5 0.01 16.0 0.9 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKF93652.1 - 0.00021 21.1 16.6 0.019 15.1 0.6 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat AAA_22 PF13401.6 KKF93652.1 - 0.00039 20.7 0.0 0.0018 18.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.6 KKF93652.1 - 0.012 16.2 5.4 10 6.7 0.2 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat SPOB_a PF14689.6 KKF93652.1 - 0.019 14.7 1.6 0.12 12.0 0.5 2.7 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain AAA_5 PF07728.14 KKF93652.1 - 0.03 14.3 0.0 6.2 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KKF93652.1 - 0.046 14.1 0.0 0.16 12.4 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KKF93652.1 - 0.16 12.4 0.0 0.6 10.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase TPR_10 PF13374.6 KKF93652.1 - 0.52 10.3 12.3 15 5.6 0.4 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKF93652.1 - 1.3 9.8 4.7 37 5.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF93652.1 - 1.9 8.7 3.9 14 6.0 1.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Radial_spoke PF04712.12 KKF93652.1 - 3.9 6.3 6.6 6.3 5.6 6.6 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein TPR_14 PF13428.6 KKF93652.1 - 5 8.2 11.2 32 5.7 0.0 5.0 5 0 0 5 5 3 0 Tetratricopeptide repeat Ribosomal_L27A PF00828.19 KKF93653.1 - 9.6e-21 74.8 0.0 1.4e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GRIM-19 PF06212.12 KKF93654.1 - 1.7e-22 79.8 0.1 3.7e-22 78.7 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein Glyco_hydro_18 PF00704.28 KKF93655.1 - 4.2e-72 243.5 0.0 5.2e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKF93655.1 - 2.5e-06 27.8 17.8 5.3e-06 26.8 17.8 1.5 1 0 0 1 1 1 1 Chitin recognition protein PPAK PF02818.15 KKF93655.1 - 3.1 8.0 4.3 37 4.6 0.6 2.5 2 0 0 2 2 2 0 PPAK motif Ribosomal_L6 PF00347.23 KKF93656.1 - 7.2e-15 55.4 0.9 1.1e-10 42.0 0.0 3.2 2 1 0 2 2 2 2 Ribosomal protein L6 Complex1_LYR_2 PF13233.6 KKF93657.1 - 1.2e-19 70.8 0.0 1.7e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Syntaxin-5_N PF11416.8 KKF93658.1 - 0.096 11.9 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain Apolipoprotein PF01442.18 KKF93658.1 - 0.19 11.6 8.4 0.96 9.3 0.7 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain FliG_C PF01706.16 KKF93658.1 - 0.37 11.0 3.6 0.81 9.9 0.1 3.0 3 0 0 3 3 3 0 FliG C-terminal domain Aha1_N PF09229.11 KKF93659.1 - 1.6e-42 145.0 0.3 3e-42 144.1 0.3 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KKF93659.1 - 1e-18 67.7 0.6 1.9e-18 66.9 0.6 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Glyco_hydro_61 PF03443.14 KKF93660.1 - 2.6e-48 164.7 0.5 5.3e-48 163.7 0.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DHHC PF01529.20 KKF93661.1 - 2.6e-33 115.0 6.4 4e-33 114.4 6.4 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase TatC PF00902.18 KKF93661.1 - 0.81 9.5 4.3 1.9 8.3 0.1 2.3 2 1 0 2 2 2 0 Sec-independent protein translocase protein (TatC) DUF3043 PF11241.8 KKF93662.1 - 0.096 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) HLH PF00010.26 KKF93663.1 - 5.7e-16 58.2 0.6 1.3e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SOG2 PF10428.9 KKF93663.1 - 0.089 12.0 18.3 0.12 11.5 18.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Cnn_1N PF07989.11 KKF93663.1 - 6 7.1 10.1 25 5.1 1.1 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Lin-8 PF03353.15 KKF93663.1 - 6.6 6.2 15.4 11 5.5 15.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ndc1_Nup PF09531.10 KKF93663.1 - 9 4.8 17.5 14 4.3 17.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_M24 PF00557.24 KKF93664.1 - 2.4e-49 167.9 0.0 5.1e-49 166.8 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 KKF93664.1 - 4.7e-17 61.9 0.0 1.3e-11 44.3 0.0 2.3 1 1 1 2 2 2 2 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.10 KKF93665.1 - 3.3e-31 108.1 0.9 1.3e-30 106.2 0.0 2.5 3 0 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.12 KKF93665.1 - 2.1e-19 69.3 0.3 3.9e-19 68.5 0.3 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KKF93665.1 - 0.097 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain Pantoate_transf PF02548.15 KKF93666.1 - 8.6e-109 362.9 1.0 1e-108 362.7 1.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KKF93666.1 - 8.3e-08 32.0 1.8 1e-07 31.7 0.2 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KKF93666.1 - 0.16 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) UQ_con PF00179.26 KKF93667.1 - 3e-36 124.1 0.0 3.8e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKF93667.1 - 0.093 13.0 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF572 PF04502.13 KKF93668.1 - 4.7e-63 213.8 0.0 5.5e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF2526 PF10735.9 KKF93668.1 - 0.061 13.5 3.3 0.082 13.1 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2526) Glyco_hydro_16 PF00722.21 KKF93669.1 - 1.8e-44 151.3 2.8 1.8e-44 151.3 2.8 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PAP1 PF08601.10 KKF93669.1 - 5.6 6.6 18.0 8 6.1 18.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Rad10 PF03834.14 KKF93670.1 - 1.3e-47 160.6 0.5 1.7e-47 160.1 0.5 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KKF93670.1 - 0.0051 17.4 0.0 0.027 15.0 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain Herpes_pp85 PF04637.12 KKF93671.1 - 0.26 9.6 1.4 0.29 9.5 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Ndc80_HEC PF03801.13 KKF93672.1 - 7.4e-60 201.0 1.5 1.4e-59 200.1 1.5 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family ABC_tran_CTD PF16326.5 KKF93672.1 - 0.0028 17.9 39.1 0.0062 16.8 6.6 5.1 4 1 1 5 5 5 3 ABC transporter C-terminal domain HALZ PF02183.18 KKF93672.1 - 0.0055 16.9 0.9 0.0055 16.9 0.9 3.4 4 0 0 4 4 3 1 Homeobox associated leucine zipper DUF5595 PF18077.1 KKF93672.1 - 0.0093 16.0 3.3 0.0093 16.0 3.3 5.4 6 1 0 6 6 5 1 Domain of unknown function (DUF5595) Fungal_TACC PF12709.7 KKF93672.1 - 0.055 13.9 0.1 0.055 13.9 0.1 5.2 3 2 2 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 KKF93672.1 - 0.22 10.9 28.8 0.53 9.6 6.3 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KKF93672.1 - 0.31 9.9 40.6 0.19 10.6 12.1 3.2 2 1 0 2 2 2 0 Spc7 kinetochore protein Filament PF00038.21 KKF93672.1 - 0.43 10.1 46.5 1.5 8.3 16.4 3.5 3 1 1 4 4 4 0 Intermediate filament protein Lebercilin PF15619.6 KKF93672.1 - 1 9.0 33.3 4.1 7.0 8.8 4.2 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Ntox28 PF15605.6 KKF93672.1 - 1.5 9.1 13.4 2.8 8.2 1.0 3.8 3 2 0 3 3 3 0 Bacterial toxin 28 TPR_MLP1_2 PF07926.12 KKF93672.1 - 2 8.5 39.3 1.5 8.9 12.4 4.4 3 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 KKF93672.1 - 2.2 7.7 43.5 2.6 7.4 14.2 3.6 2 2 1 3 3 3 0 Golgin subfamily A member 5 FliJ PF02050.16 KKF93672.1 - 2.5 8.3 29.6 0.055 13.7 5.7 4.1 2 2 2 4 4 4 0 Flagellar FliJ protein DHR10 PF18595.1 KKF93672.1 - 8.2 6.5 42.3 1.3 9.1 15.1 4.1 2 2 1 3 3 3 0 Designed helical repeat protein 10 domain Pex14_N PF04695.13 KKF93673.1 - 6e-40 137.5 4.1 6e-40 137.5 4.1 2.4 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Prominin PF05478.11 KKF93673.1 - 0.0016 16.5 1.5 0.0021 16.1 1.5 1.1 1 0 0 1 1 1 1 Prominin DUF1043 PF06295.12 KKF93673.1 - 0.0034 17.4 2.0 0.0034 17.4 2.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF1043) SF-assemblin PF06705.11 KKF93673.1 - 0.0035 16.7 6.0 0.005 16.2 6.0 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin Wtap PF17098.5 KKF93673.1 - 0.0063 16.5 3.7 0.0063 16.5 3.7 1.9 2 0 0 2 2 1 1 WTAP/Mum2p family LXG PF04740.12 KKF93673.1 - 0.0097 15.6 3.8 0.016 14.9 3.8 1.3 1 0 0 1 1 1 1 LXG domain of WXG superfamily SlyX PF04102.12 KKF93673.1 - 0.01 16.5 2.6 0.01 16.5 2.6 2.7 3 1 1 4 4 2 1 SlyX LMBR1 PF04791.16 KKF93673.1 - 0.01 14.8 0.1 0.014 14.3 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3496 PF12001.8 KKF93673.1 - 0.012 16.0 0.5 0.025 15.0 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3496) CR6_interact PF10147.9 KKF93673.1 - 0.018 14.8 0.4 0.027 14.2 0.4 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 SHE3 PF17078.5 KKF93673.1 - 0.024 14.4 4.6 0.038 13.7 4.6 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 BEX PF04538.12 KKF93673.1 - 0.025 15.2 0.3 0.046 14.3 0.3 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family zf-C4H2 PF10146.9 KKF93673.1 - 0.025 14.9 10.7 0.087 13.1 0.3 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein HMMR_N PF15905.5 KKF93673.1 - 0.034 13.6 8.2 0.055 12.9 8.2 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FAM76 PF16046.5 KKF93673.1 - 0.049 13.0 1.0 0.075 12.4 1.0 1.3 1 0 0 1 1 1 0 FAM76 protein TFIIA PF03153.13 KKF93673.1 - 0.061 13.3 6.3 0.02 14.9 3.7 1.5 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit MAP65_ASE1 PF03999.12 KKF93673.1 - 0.075 11.7 3.8 3 6.4 6.5 1.9 1 1 1 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) CSF-1 PF05337.11 KKF93673.1 - 0.11 12.6 1.6 0.19 11.9 1.6 1.3 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) DUF3461 PF11944.8 KKF93673.1 - 0.15 12.2 1.5 0.26 11.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Golgin_A5 PF09787.9 KKF93673.1 - 0.16 11.4 7.3 0.26 10.7 7.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3584 PF12128.8 KKF93673.1 - 0.2 9.2 8.4 0.32 8.5 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KKF93673.1 - 0.21 10.5 8.9 0.34 9.8 8.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 KKF93673.1 - 0.27 10.8 5.9 0.3 10.6 4.1 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Jnk-SapK_ap_N PF09744.9 KKF93673.1 - 0.28 11.4 9.2 0.53 10.5 9.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Allexi_40kDa PF05549.11 KKF93673.1 - 0.28 10.7 2.2 0.17 11.4 0.2 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein AAA_13 PF13166.6 KKF93673.1 - 0.43 9.2 7.2 0.71 8.4 7.2 1.2 1 0 0 1 1 1 0 AAA domain COG2 PF06148.11 KKF93673.1 - 0.46 10.6 3.1 0.51 10.4 2.1 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 KKF93673.1 - 0.52 10.8 6.8 0.68 10.4 0.7 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 KKF93673.1 - 0.68 9.1 2.8 1.1 8.5 2.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF148 PF02520.17 KKF93673.1 - 1 9.5 6.3 0.91 9.7 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 TolA_bind_tri PF16331.5 KKF93673.1 - 1.5 9.0 7.5 0.47 10.6 3.7 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation Laminin_II PF06009.12 KKF93673.1 - 1.6 8.7 12.3 0.085 12.9 6.9 1.5 2 0 0 2 2 1 0 Laminin Domain II V_ATPase_I PF01496.19 KKF93673.1 - 1.7 6.5 4.8 2.3 6.0 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.12 KKF93673.1 - 2.2 8.3 8.5 0.72 9.9 1.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.6 KKF93673.1 - 2.3 8.6 21.3 1.5 9.1 9.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) UPF0242 PF06785.11 KKF93673.1 - 2.7 8.1 6.5 4.4 7.3 6.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LELP1 PF15042.6 KKF93673.1 - 3 8.2 10.1 3.3 8.1 2.4 2.3 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 DUF16 PF01519.16 KKF93673.1 - 3.3 8.3 6.6 2.9e+02 2.0 6.6 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 Abhydrolase_3 PF07859.13 KKF93674.1 - 7.9e-44 150.0 0.0 1.1e-43 149.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKF93674.1 - 0.0014 17.6 0.1 0.013 14.4 0.1 2.2 1 1 0 1 1 1 1 Steryl acetyl hydrolase FAD_binding_4 PF01565.23 KKF93675.1 - 4.1e-15 55.7 0.0 7.2e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HMG_CoA_synt_C PF08540.10 KKF93676.1 - 1.3e-107 359.6 0.2 1.6e-107 359.3 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KKF93676.1 - 4.7e-96 319.6 1.1 7.1e-96 319.1 1.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF5040 PF16443.5 KKF93676.1 - 0.056 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) Med3 PF11593.8 KKF93677.1 - 0.0014 17.9 6.1 0.002 17.4 6.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal NACHT_N PF17100.5 KKF93678.1 - 2e-49 168.4 0.7 1.1e-48 166.0 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KKF93678.1 - 1.1e-19 71.0 0.1 3e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KKF93678.1 - 0.0035 17.8 0.0 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KKF93678.1 - 0.039 14.3 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KKF93678.1 - 0.043 13.0 0.5 6.5 5.8 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.14 KKF93678.1 - 0.047 12.9 0.6 0.36 10.0 0.6 2.4 1 1 0 1 1 1 0 KAP family P-loop domain DUF1836 PF08876.11 KKF93678.1 - 0.08 13.0 0.5 0.3 11.2 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) Muted PF14942.6 KKF93678.1 - 0.095 13.0 5.0 0.16 12.3 1.5 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein AAA_11 PF13086.6 KKF93678.1 - 0.74 9.6 0.0 0.74 9.6 0.0 2.6 2 1 0 3 3 3 0 AAA domain WD40 PF00400.32 KKF93679.1 - 1.9e-81 265.8 34.1 1.7e-11 44.5 0.4 8.0 8 0 0 8 8 7 7 WD domain, G-beta repeat NACHT_N PF17100.5 KKF93679.1 - 1.4e-46 159.2 5.2 3.3e-31 108.9 0.4 3.2 3 1 1 4 4 3 2 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 KKF93679.1 - 6.8e-32 109.6 8.1 0.00033 20.9 0.0 7.7 2 1 6 8 8 7 7 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KKF93679.1 - 1.9e-19 70.2 0.0 4.9e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KKF93679.1 - 2.3e-07 30.5 0.1 0.2 10.9 0.0 4.4 3 2 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 KKF93679.1 - 7.3e-06 25.2 12.5 0.049 12.6 2.0 5.2 1 1 5 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein CDtoxinA PF03498.14 KKF93679.1 - 2.8e-05 23.8 0.7 4.3 6.9 0.1 4.9 1 1 2 3 3 3 1 Cytolethal distending toxin A/C domain DUF5114 PF17141.4 KKF93679.1 - 0.006 17.1 0.5 23 5.6 0.0 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF5114) SurE PF01975.17 KKF93679.1 - 0.042 13.6 0.2 6.1 6.6 0.0 3.1 1 1 1 2 2 2 0 Survival protein SurE Me-amine-dh_H PF06433.11 KKF93679.1 - 0.1 11.5 0.1 2.9 6.7 0.0 2.8 1 1 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.16 KKF93679.1 - 0.11 11.0 3.1 5.6 5.4 0.7 3.1 1 1 3 4 4 4 0 Cytochrome D1 heme domain AAA_19 PF13245.6 KKF93679.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KKF93679.1 - 0.29 10.9 5.2 1.9 8.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain CCDC53 PF10152.9 KKF93680.1 - 0.85 10.0 6.1 10 6.5 6.1 2.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Frag1 PF10277.9 KKF93681.1 - 1.8e-19 70.2 14.3 2.2e-19 69.9 14.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EamA PF00892.20 KKF93681.1 - 0.027 14.7 6.8 0.69 10.1 1.3 2.1 2 0 0 2 2 2 0 EamA-like transporter family EMP70 PF02990.16 KKF93681.1 - 0.095 11.4 3.8 0.12 11.0 3.8 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 Pmp3 PF01679.17 KKF93681.1 - 0.36 11.1 5.4 0.41 10.9 1.0 2.5 2 0 0 2 2 2 0 Proteolipid membrane potential modulator Phage_holin_3_7 PF05449.11 KKF93681.1 - 0.61 10.1 5.3 4.9 7.2 0.6 2.3 2 0 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 DUF4229 PF14012.6 KKF93681.1 - 0.83 9.8 7.7 2.1 8.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Helicase_C PF00271.31 KKF93682.1 - 6.3e-19 68.4 0.1 1.7e-18 67.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KKF93682.1 - 4e-16 58.7 0.0 7.9e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 KKF93682.1 - 0.001 18.4 0.8 0.0024 17.1 0.8 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KKF93682.1 - 0.014 15.4 1.9 0.026 14.5 0.6 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Aminotran_1_2 PF00155.21 KKF93683.1 - 2.3e-81 273.8 0.7 9.2e-81 271.8 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKF93683.1 - 1.8e-05 23.5 0.1 3.2e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KKF93683.1 - 0.00022 20.3 0.1 0.00038 19.5 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKF93683.1 - 0.012 14.9 1.4 0.032 13.5 1.4 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Lipase_GDSL_2 PF13472.6 KKF93685.1 - 3.2e-19 70.0 0.1 5.5e-19 69.2 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKF93685.1 - 9.5e-14 51.8 0.0 1.2e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BP28CT PF08146.12 KKF93686.1 - 3.5e-36 124.4 0.0 1.3e-35 122.6 0.0 2.1 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KKF93686.1 - 1.1e-24 87.0 0.1 1.1e-24 87.0 0.1 5.2 6 0 0 6 6 6 2 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KKF93686.1 - 2.2e-05 24.3 11.6 0.014 15.6 0.1 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KKF93686.1 - 2.9e-05 24.4 7.8 1.2 9.5 0.0 6.3 5 1 1 6 6 6 2 HEAT repeats CdvA PF18822.1 KKF93686.1 - 0.0035 17.2 0.4 0.14 12.0 0.1 2.7 2 0 0 2 2 2 1 CdvA-like coiled-coil domain HEAT_EZ PF13513.6 KKF93686.1 - 0.011 16.2 15.9 0.57 10.8 0.7 7.2 6 0 0 6 6 6 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KKF93686.1 - 0.016 15.8 0.0 69 4.1 0.0 4.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Ykof PF07615.11 KKF93686.1 - 0.066 13.7 0.1 17 6.0 0.0 3.9 4 0 0 4 4 4 0 YKOF-related Family CDH-cyt PF16010.5 KKF93687.1 - 2.4e-50 170.8 3.5 1.7e-49 167.9 0.3 2.5 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KKF93687.1 - 9.9e-33 113.8 0.0 1.7e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKF93687.1 - 4.6e-17 62.9 0.4 1.9e-16 60.9 0.4 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKF93687.1 - 4.4e-08 32.6 2.9 2.6e-05 23.5 0.7 3.1 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 KKF93687.1 - 6.5e-06 26.0 0.8 0.00051 19.7 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKF93687.1 - 0.00013 22.2 0.2 0.00041 20.5 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKF93687.1 - 0.0005 18.9 1.0 0.0016 17.2 0.3 1.9 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KKF93687.1 - 0.0067 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KKF93687.1 - 0.01 15.1 0.4 0.019 14.2 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KKF93687.1 - 0.014 14.6 0.1 0.029 13.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SpoVIF PF14069.6 KKF93687.1 - 0.036 13.8 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Stage VI sporulation protein F FAD_oxidored PF12831.7 KKF93687.1 - 0.064 12.6 1.4 0.11 11.9 0.4 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KKF93687.1 - 0.33 11.5 2.0 0.3 11.7 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.29 KKF93688.1 - 3.1e-39 134.6 0.5 4.8e-39 133.9 0.5 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF93688.1 - 2.7e-31 108.2 0.1 7.1e-31 106.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF93688.1 - 1.2e-06 28.7 0.0 2.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KKF93688.1 - 0.16 11.9 1.0 0.36 10.8 0.1 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain Methyltransf_23 PF13489.6 KKF93689.1 - 1.3e-21 77.2 0.0 2.1e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF93689.1 - 1.3e-14 54.6 0.0 2.8e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF93689.1 - 1.1e-13 51.6 0.0 3.2e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF93689.1 - 2e-09 37.4 0.0 0.0019 18.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KKF93689.1 - 1.4e-08 35.4 0.0 2.2e-07 31.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKF93689.1 - 2.9e-06 26.8 0.0 8.5e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KKF93689.1 - 0.0012 18.3 0.0 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KKF93689.1 - 0.0069 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KKF93689.1 - 0.008 15.7 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KKF93689.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KKF93689.1 - 0.047 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Nucleoside_tran PF01733.18 KKF93690.1 - 7.2e-09 35.5 2.2 7.2e-09 35.5 2.2 2.9 3 1 0 3 3 3 2 Nucleoside transporter Glyco_transf_34 PF05637.12 KKF93691.1 - 1.4e-57 195.2 0.0 1.7e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Pkinase PF00069.25 KKF93692.1 - 2.1e-71 240.4 0.0 3.2e-71 239.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF93692.1 - 6.5e-32 110.8 0.0 1.2e-31 109.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF93692.1 - 0.0029 16.9 0.1 0.77 9.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KKF93692.1 - 0.0073 15.7 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_U4 PF03419.13 KKF93693.1 - 0.14 11.4 0.1 0.33 10.2 0.1 1.6 1 0 0 1 1 1 0 Sporulation factor SpoIIGA RhoGEF PF00621.20 KKF93695.1 - 5.4e-29 101.7 1.7 1.6e-28 100.2 0.0 2.4 3 0 0 3 3 3 1 RhoGEF domain BAR PF03114.18 KKF93695.1 - 3.1e-09 36.8 2.0 1.3e-08 34.8 2.0 2.0 1 1 0 1 1 1 1 BAR domain LPD13 PF18825.1 KKF93695.1 - 0.0075 16.0 0.1 0.024 14.4 0.1 1.8 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 13 Tymo_45kd_70kd PF03251.13 KKF93695.1 - 0.24 10.3 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Tymovirus 45/70Kd protein Rx_N PF18052.1 KKF93695.1 - 1.2 9.5 4.4 9.9 6.5 0.1 3.4 4 1 0 4 4 4 0 Rx N-terminal domain MFS_2 PF13347.6 KKF93696.1 - 2.1e-06 26.6 11.1 4.1e-06 25.6 6.8 2.8 3 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KKF93696.1 - 0.0026 16.7 0.2 0.0026 16.7 0.2 2.2 2 2 0 2 2 2 1 MFS_1 like family GFO_IDH_MocA PF01408.22 KKF93697.1 - 8.2e-11 42.8 0.0 2.3e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKF93697.1 - 0.00016 21.6 0.1 0.00037 20.5 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Amidoligase_2 PF12224.8 KKF93699.1 - 5.4e-15 55.7 0.0 1e-12 48.3 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme Sporozoite_P67 PF05642.11 KKF93700.1 - 2.7 6.0 11.3 2.7 6.0 11.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF948 PF06103.11 KKF93702.1 - 0.88 9.9 11.9 4 7.8 0.6 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1798 PF08807.10 KKF93702.1 - 1.1 9.4 6.9 0.48 10.6 1.6 2.6 2 1 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Sirohm_synth_C PF14823.6 KKF93702.1 - 1.9 8.2 6.1 5.9 6.6 0.1 3.2 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal FAP206 PF12018.8 KKF93702.1 - 3.7 7.0 12.1 0.21 11.0 5.9 2.0 1 1 0 2 2 2 0 Domain of unknown function DUF3453 PF11935.8 KKF93703.1 - 4.4e-64 216.2 0.1 6.1e-62 209.2 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3453) Erg28 PF03694.13 KKF93703.1 - 0.22 11.9 0.4 0.4 11.1 0.4 1.3 1 0 0 1 1 1 0 Erg28 like protein Sds3 PF08598.11 KKF93704.1 - 2.6e-12 47.2 0.7 2.6e-12 47.2 0.7 1.8 2 0 0 2 2 2 1 Sds3-like RRM_1 PF00076.22 KKF93705.1 - 1.3e-13 50.5 0.1 9.3e-08 31.8 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flot PF15975.5 KKF93705.1 - 0.02 15.1 0.1 0.02 15.1 0.1 2.1 2 0 0 2 2 2 0 Flotillin RunxI PF08504.11 KKF93705.1 - 0.6 10.9 4.8 1.6 9.5 3.1 2.7 2 0 0 2 2 2 0 Runx inhibition domain Tubulin_C PF03953.17 KKF93706.1 - 4.7e-45 152.8 0.0 6.9e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KKF93706.1 - 1.6e-11 44.8 0.0 2.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain PFK PF00365.20 KKF93707.1 - 4.1e-168 557.9 0.1 7.1e-84 281.5 0.0 3.1 2 1 1 3 3 3 3 Phosphofructokinase UVR PF02151.19 KKF93707.1 - 0.081 12.7 0.2 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Med17 PF10156.9 KKF93708.1 - 2.6e-36 125.4 0.1 3.6e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PI-PLC-Y PF00387.19 KKF93709.1 - 1.4e-36 125.3 0.0 2.7e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-X PF00388.19 KKF93709.1 - 3.2e-24 85.2 6.5 6.2e-22 77.8 0.0 3.1 2 1 1 3 3 3 2 Phosphatidylinositol-specific phospholipase C, X domain BPL_LplA_LipB_2 PF16917.5 KKF93709.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family RRM_1 PF00076.22 KKF93710.1 - 5.2e-19 67.8 0.0 9.6e-19 67.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KKF93710.1 - 1.7e-05 25.3 7.6 1.7e-05 25.3 7.6 3.3 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.11 KKF93710.1 - 0.0041 17.1 0.0 0.0079 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 KKF93710.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Anp1 PF03452.14 KKF93711.1 - 1.1e-100 336.4 0.1 1.3e-100 336.2 0.1 1.0 1 0 0 1 1 1 1 Anp1 Glyco_transf_8 PF01501.20 KKF93711.1 - 0.038 13.6 0.2 0.05 13.1 0.2 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 Cgr1 PF03879.14 KKF93712.1 - 2.6e-32 111.4 28.7 3e-32 111.2 28.7 1.0 1 0 0 1 1 1 1 Cgr1 family Vfa1 PF08432.10 KKF93712.1 - 0.24 11.7 10.7 0.27 11.5 10.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3347 PF11827.8 KKF93712.1 - 1.4 9.1 9.3 0.39 10.9 6.8 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Prominin PF05478.11 KKF93713.1 - 0.00019 19.6 0.6 0.00023 19.3 0.6 1.0 1 0 0 1 1 1 1 Prominin Snapin_Pallidin PF14712.6 KKF93713.1 - 0.0013 19.1 7.4 0.21 12.0 1.0 2.3 2 0 0 2 2 2 2 Snapin/Pallidin Spectrin PF00435.21 KKF93713.1 - 0.011 16.2 4.5 0.63 10.6 0.1 2.3 1 1 1 2 2 2 0 Spectrin repeat DUF4618 PF15397.6 KKF93713.1 - 0.014 14.9 4.6 0.02 14.3 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2207 PF09972.9 KKF93713.1 - 0.039 12.7 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MCU PF04678.13 KKF93713.1 - 0.044 13.9 4.5 0.16 12.0 4.5 1.9 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Sec34 PF04136.15 KKF93713.1 - 0.059 13.3 2.0 0.12 12.3 1.8 1.7 1 1 0 1 1 1 0 Sec34-like family BORCS6 PF10157.9 KKF93713.1 - 0.061 13.6 2.7 1.2 9.3 1.0 2.2 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 DUF4391 PF14335.6 KKF93713.1 - 0.067 12.9 1.5 0.089 12.5 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Fib_alpha PF08702.10 KKF93713.1 - 0.071 13.3 3.4 0.27 11.4 3.4 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 KKF93713.1 - 0.08 13.3 2.7 0.33 11.3 1.8 2.4 2 1 0 2 2 2 0 Syntaxin-like protein GAS PF13851.6 KKF93713.1 - 0.12 11.7 6.8 0.041 13.2 2.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HR1 PF02185.16 KKF93713.1 - 0.17 12.0 2.3 3.1 8.0 2.3 2.4 1 1 0 1 1 1 0 Hr1 repeat Med9 PF07544.13 KKF93713.1 - 0.3 11.2 2.3 0.59 10.3 0.4 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.9 KKF93713.1 - 0.66 10.3 4.8 2 8.8 1.2 2.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 KKF93713.1 - 4.3 7.4 8.6 2 8.4 4.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec20 PF03908.13 KKF93713.1 - 8.4 6.4 9.3 0.27 11.2 0.3 2.6 3 0 0 3 3 3 0 Sec20 DUF1664 PF07889.12 KKF93713.1 - 8.5 6.4 11.0 0.12 12.4 2.3 2.3 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) DUF3818 PF12825.7 KKF93714.1 - 1.7e-130 435.0 4.9 1.7e-130 435.0 4.9 1.5 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KKF93714.1 - 2.4e-25 89.0 0.1 5.4e-25 87.9 0.1 1.6 1 0 0 1 1 1 1 PX-associated RE_Bpu10I PF09549.10 KKF93714.1 - 0.0031 17.1 0.5 0.0076 15.9 0.5 1.6 1 0 0 1 1 1 1 Bpu10I restriction endonuclease DUF4050 PF13259.6 KKF93714.1 - 0.23 11.7 2.1 0.53 10.6 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) FAD_binding_2 PF00890.24 KKF93715.1 - 1.1e-123 413.4 2.7 1.4e-123 413.1 2.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KKF93715.1 - 6.2e-44 149.1 0.3 9.7e-44 148.4 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KKF93715.1 - 6.8e-07 28.8 0.4 0.00039 19.7 0.3 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKF93715.1 - 1.1e-05 24.9 0.2 0.0053 16.0 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KKF93715.1 - 2.8e-05 23.4 1.6 0.016 14.3 2.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KKF93715.1 - 0.0021 17.4 0.2 0.0049 16.2 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKF93715.1 - 0.01 15.5 0.5 0.021 14.4 0.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KKF93715.1 - 0.067 11.9 0.3 0.17 10.6 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Oxysterol_BP PF01237.18 KKF93717.1 - 7.3e-71 239.0 2.1 7.1e-53 179.8 0.0 3.0 1 1 2 3 3 3 3 Oxysterol-binding protein zf-CCCH PF00642.24 KKF93718.1 - 1.9e-08 34.0 18.6 5.3e-07 29.4 2.6 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KKF93718.1 - 0.0092 15.8 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KKF93718.1 - 0.012 15.6 2.9 0.012 15.6 2.9 3.3 3 0 0 3 3 3 0 Zinc finger domain Torus PF16131.5 KKF93718.1 - 0.033 14.9 6.3 0.39 11.4 0.8 2.5 2 1 0 2 2 2 0 Torus domain SCRG1 PF15224.6 KKF93718.1 - 0.18 11.9 5.0 0.42 10.7 0.2 2.5 2 0 0 2 2 2 0 Scrapie-responsive protein 1 Tachystatin_B PF11478.8 KKF93718.1 - 2.5 8.1 10.5 0.19 11.7 3.1 2.6 3 0 0 3 3 3 0 Antimicrobial chitin binding protein tachystatin B ELMO_CED12 PF04727.13 KKF93719.1 - 6.5e-46 156.7 0.1 1.1e-45 155.9 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KKF93719.1 - 3.3e-34 118.3 0.0 9e-34 116.9 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KKF93719.1 - 2.1e-13 50.5 0.0 5.5e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) DUF4187 PF13821.6 KKF93720.1 - 1e-18 66.8 2.7 1e-18 66.8 2.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KKF93720.1 - 3.4e-08 33.2 6.3 6.4e-08 32.4 6.3 1.5 1 0 0 1 1 1 1 G-patch domain SHR3_chaperone PF08229.11 KKF93721.1 - 3e-73 244.8 0.0 3.4e-73 244.6 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 KKF93721.1 - 0.028 14.4 2.5 0.025 14.5 0.9 1.7 2 1 0 2 2 2 0 Family of unknown function (DUF5453) tRNA-synt_1 PF00133.22 KKF93722.1 - 7.3e-197 655.3 0.6 1.7e-195 650.8 0.6 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKF93722.1 - 3.5e-33 114.7 1.8 7.4e-33 113.7 1.8 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KKF93722.1 - 9.6e-14 51.3 0.8 3.3e-10 39.8 0.0 2.8 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KKF93722.1 - 3e-08 32.8 0.3 0.0026 16.6 0.1 4.3 3 2 1 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 KKF93722.1 - 9.6e-05 22.6 2.7 0.00034 20.8 2.7 2.0 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm PepSY PF03413.19 KKF93722.1 - 0.098 13.2 0.0 0.35 11.4 0.0 2.0 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF724 PF05266.14 KKF93722.1 - 2.9 7.7 6.6 0.48 10.2 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fungal_trans PF04082.18 KKF93723.1 - 2.7e-10 39.7 0.2 6.1e-10 38.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain AA_permease PF00324.21 KKF93724.1 - 1.7e-123 412.8 43.3 2e-123 412.5 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKF93724.1 - 8.8e-30 103.9 47.3 1.2e-29 103.5 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2263 PF10021.9 KKF93725.1 - 1.2e-20 74.3 1.2 7.6e-19 68.5 1.2 2.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KKF93725.1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Macro domain PhoLip_ATPase_C PF16212.5 KKF93726.1 - 8.4e-68 228.8 12.7 1.7e-67 227.8 12.7 1.5 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKF93726.1 - 6.4e-23 80.2 0.2 6.4e-23 80.2 0.2 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KKF93726.1 - 1.1e-11 44.6 0.0 9.2e-11 41.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KKF93726.1 - 9.8e-11 41.5 0.0 2.1e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KKF93726.1 - 1.8e-10 41.5 0.1 5.6e-06 26.8 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKF93726.1 - 0.021 14.6 0.2 0.057 13.1 0.2 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ESSS PF10183.9 KKF93726.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2909 PF11137.8 KKF93726.1 - 0.068 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) VPS9 PF02204.18 KKF93727.1 - 4.5e-26 91.1 0.1 7.3e-26 90.4 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KKF93727.1 - 2.8e-16 59.6 0.2 5.6e-16 58.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) PHO4 PF01384.20 KKF93728.1 - 3.5e-99 332.0 21.5 4.1e-99 331.8 21.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family Fungal_trans PF04082.18 KKF93729.1 - 2.6e-09 36.5 0.0 2.6e-09 36.5 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain RR_TM4-6 PF06459.12 KKF93729.1 - 0.00013 21.9 19.8 0.00013 21.9 19.8 1.8 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 KKF93729.1 - 0.00029 19.3 36.8 0.00029 19.3 36.8 2.2 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 KKF93729.1 - 0.014 15.4 92.3 0.43 10.5 62.7 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 KKF93729.1 - 0.084 11.3 6.4 0.13 10.6 6.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 KKF93729.1 - 0.088 11.7 6.7 0.16 10.8 6.7 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 KKF93729.1 - 1.2 7.8 40.3 0.04 12.7 27.6 2.3 2 0 0 2 2 2 0 Presenilin PA26 PF04636.13 KKF93729.1 - 1.3 7.8 17.8 3.1 6.6 17.8 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Borrelia_P83 PF05262.11 KKF93729.1 - 6.3 5.2 22.2 11 4.4 22.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4746 PF15928.5 KKF93729.1 - 8.7 5.7 18.7 18 4.6 18.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Fungal_trans PF04082.18 KKF93730.1 - 8e-15 54.6 0.0 1.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF93730.1 - 6.8e-08 32.5 8.9 1.1e-07 31.9 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tape_meas_lam_C PF09718.10 KKF93731.1 - 0.019 15.1 5.3 0.11 12.7 1.4 2.7 2 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) YtxH PF12732.7 KKF93731.1 - 0.2 12.2 0.1 0.2 12.2 0.1 2.3 2 0 0 2 2 2 0 YtxH-like protein SET PF00856.28 KKF93732.1 - 2.3e-10 41.1 0.1 1.5e-09 38.4 0.1 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KKF93732.1 - 3.3e-06 27.1 12.1 3.3e-06 27.1 12.1 2.0 2 0 0 2 2 2 1 MYND finger TMF_TATA_bd PF12325.8 KKF93733.1 - 0.00059 20.0 14.1 0.1 12.8 8.7 3.5 1 1 2 3 3 3 3 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KKF93733.1 - 0.0058 17.1 17.9 0.55 10.7 17.1 2.4 1 1 1 2 2 2 1 Fez1 Baculo_PEP_C PF04513.12 KKF93733.1 - 0.036 14.1 0.3 0.036 14.1 0.3 3.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KKF93733.1 - 0.083 12.9 20.0 0.24 11.4 0.3 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Filament PF00038.21 KKF93733.1 - 0.089 12.4 18.1 0.49 9.9 0.1 2.9 1 1 0 1 1 1 0 Intermediate filament protein DUF2203 PF09969.9 KKF93733.1 - 0.22 12.3 11.7 2.1 9.1 5.1 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) zf-C4H2 PF10146.9 KKF93733.1 - 0.36 11.1 23.2 0.1 12.9 14.1 2.9 1 1 2 3 3 3 0 Zinc finger-containing protein TolA_bind_tri PF16331.5 KKF93733.1 - 0.78 9.9 11.8 17 5.6 12.4 2.8 2 1 0 2 2 2 0 TolA binding protein trimerisation CCDC84 PF14968.6 KKF93733.1 - 1.3 8.6 9.0 2.1 7.9 9.0 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 Cauli_AT PF03233.13 KKF93733.1 - 1.5 8.8 7.3 0.24 11.3 1.6 2.3 1 1 1 2 2 2 0 Aphid transmission protein Spc7 PF08317.11 KKF93733.1 - 1.6 7.5 19.4 0.79 8.5 1.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 KKF93733.1 - 1.7 9.3 10.3 29 5.4 6.7 3.1 1 1 1 2 2 2 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 KKF93733.1 - 1.7 8.9 20.3 1.9 8.8 4.0 3.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 KKF93733.1 - 2.8 8.5 17.7 0.14 12.6 0.5 4.7 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KKF93733.1 - 3.5 8.1 10.1 23 5.5 0.0 4.2 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) AIP3 PF03915.13 KKF93733.1 - 4.7 6.2 23.8 0.44 9.6 15.3 2.4 1 1 2 3 3 3 0 Actin interacting protein 3 RNase_T PF00929.24 KKF93734.1 - 2.3e-07 31.5 0.0 7e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Exonuclease SMYLE_N PF18615.1 KKF93734.1 - 0.045 13.3 0.7 0.074 12.6 0.7 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Tox-GHH PF15636.6 KKF93734.1 - 7.5 6.6 6.2 18 5.4 2.3 2.7 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin TPR_1 PF00515.28 KKF93735.1 - 3.4e-26 89.9 1.3 1e-06 28.3 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKF93735.1 - 4.3e-24 82.6 2.0 8.8e-06 25.5 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KKF93735.1 - 1e-17 64.5 2.5 3.1e-07 30.9 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKF93735.1 - 6.9e-17 60.9 3.1 2.1e-07 30.5 0.0 5.1 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.6 KKF93735.1 - 3.3e-16 58.6 2.7 6.6e-05 23.4 0.1 5.9 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKF93735.1 - 3.4e-14 53.1 2.3 0.0011 19.4 0.1 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKF93735.1 - 5.6e-14 51.1 0.9 0.00058 19.9 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKF93735.1 - 4.7e-12 45.4 2.3 0.07 13.5 0.1 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KKF93735.1 - 1.1e-08 35.1 0.5 0.0012 19.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKF93735.1 - 6.1e-08 32.8 10.7 0.0061 16.8 1.1 5.0 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKF93735.1 - 8.7e-08 31.7 0.9 0.45 10.7 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 KKF93735.1 - 1.7e-06 28.3 4.4 0.21 11.9 0.0 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KKF93735.1 - 0.00011 21.5 0.3 0.11 11.6 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KKF93735.1 - 0.0042 16.2 0.2 1.9 7.6 0.0 2.4 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference ANAPC3 PF12895.7 KKF93735.1 - 0.0098 16.1 1.3 0.6 10.4 0.1 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KKF93735.1 - 0.011 16.4 6.4 19 6.1 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 KKF93735.1 - 0.087 12.8 0.1 20 5.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RPAP1_C PF08620.10 KKF93735.1 - 0.16 12.1 0.4 5.4 7.2 0.1 3.0 3 0 0 3 3 3 0 RPAP1-like, C-terminal RRM_1 PF00076.22 KKF93736.1 - 2.1e-31 107.6 0.0 7.1e-17 61.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.26 KKF93736.1 - 3e-13 49.5 3.4 7.5e-13 48.2 3.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRM_5 PF13893.6 KKF93736.1 - 4.8e-08 32.6 0.0 4.4e-07 29.5 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2781 PF10914.8 KKF93737.1 - 1.6e-31 109.7 12.8 1.8e-31 109.6 12.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Nucleoporin_N PF08801.11 KKF93738.1 - 1.1e-101 340.8 0.2 1.7e-101 340.1 0.2 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KKF93738.1 - 4.3e-47 161.2 1.3 5.8e-45 154.1 0.1 2.1 1 1 1 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal BAR_3 PF16746.5 KKF93738.1 - 0.046 13.4 0.5 0.089 12.5 0.1 1.6 2 0 0 2 2 2 0 BAR domain of APPL family DUF1824 PF08854.10 KKF93738.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) adh_short PF00106.25 KKF93739.1 - 1e-38 132.8 0.3 1.4e-38 132.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF93739.1 - 3.5e-24 85.6 0.0 5e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF93739.1 - 6.2e-07 29.5 0.1 1.2e-06 28.5 0.1 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKF93739.1 - 0.0027 16.9 0.2 0.0042 16.2 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KKF93739.1 - 0.011 15.9 0.2 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KKF93739.1 - 0.02 14.8 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Ldh_1_N PF00056.23 KKF93739.1 - 0.088 12.9 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KKF93739.1 - 0.14 12.1 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Erg28 PF03694.13 KKF93740.1 - 6.7e-29 100.5 0.1 9.3e-29 100.0 0.1 1.2 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.22 KKF93741.1 - 6.7e-66 222.2 0.0 1.7e-65 220.9 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KKF93741.1 - 2.4e-58 196.6 0.0 3.9e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KKF93741.1 - 0.0034 18.1 0.0 0.2 12.4 0.0 2.5 2 0 0 2 2 2 1 HIT domain Myb_DNA-binding PF00249.31 KKF93742.1 - 3.6e-11 43.1 0.6 1.5e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKF93742.1 - 1.9e-06 28.0 0.1 1.6e-05 25.1 0.0 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain SWIRM PF04433.17 KKF93742.1 - 2.3e-05 24.7 0.0 5.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain DFRP_C PF16543.5 KKF93742.1 - 0.31 11.5 0.1 0.31 11.5 0.1 2.2 3 0 0 3 3 3 0 DRG Family Regulatory Proteins, Tma46 Rhodanese PF00581.20 KKF93743.1 - 1.8e-13 50.9 0.0 2.1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain C2-set_2 PF08205.12 KKF93743.1 - 0.072 13.2 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF2332 PF10094.9 KKF93743.1 - 0.11 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) HD_3 PF13023.6 KKF93744.1 - 8.5e-48 162.4 0.0 1e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KKF93744.1 - 1.4e-11 44.5 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KKF93744.1 - 0.00064 19.9 0.0 0.0013 19.0 0.0 1.6 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 KKF93744.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 HDOD domain Pkinase PF00069.25 KKF93746.1 - 2.5e-53 181.1 0.0 3.4e-52 177.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF93746.1 - 8.7e-24 84.2 0.0 2.2e-17 63.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KKF93746.1 - 0.00012 21.1 0.1 0.00017 20.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KKF93746.1 - 0.00018 21.5 2.0 0.012 15.6 0.2 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKF93746.1 - 0.013 14.9 0.7 0.027 13.8 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KKF93746.1 - 0.025 13.9 0.1 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KKF93746.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 KKF93746.1 - 0.21 10.6 0.1 0.31 10.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Clr2 PF10383.9 KKF93747.1 - 6.5e-16 59.4 0.1 2e-15 57.9 0.0 1.8 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 KKF93747.1 - 1.5e-06 28.9 1.6 2.2e-05 25.2 2.4 2.4 2 1 0 2 2 2 1 Transcription-silencing protein, cryptic loci regulator Clr2 Zn_ribbon_17 PF17120.5 KKF93748.1 - 0.0012 18.5 2.5 0.0012 18.5 2.5 3.3 3 0 0 3 3 3 2 Zinc-ribbon, C4HC2 type FYVE_2 PF02318.16 KKF93748.1 - 0.51 10.6 21.8 1.7 8.9 2.3 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger zf-C3HC4_2 PF13923.6 KKF93748.1 - 3.6 7.5 36.5 3.8 7.4 6.0 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 KKF93749.1 - 3.8e-07 29.9 0.1 7.8e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKF93749.1 - 0.0011 18.8 0.2 0.002 18.0 0.2 1.4 1 0 0 1 1 1 1 F-box domain CBP_BcsO PF17037.5 KKF93749.1 - 0.0036 17.5 0.0 0.0095 16.1 0.0 1.7 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsO Serglycin PF04360.12 KKF93749.1 - 0.009 16.0 6.0 0.03 14.3 6.0 1.9 1 0 0 1 1 1 1 Serglycin F-box_4 PF15966.5 KKF93749.1 - 0.026 14.4 0.1 0.06 13.2 0.1 1.6 1 0 0 1 1 1 0 F-box UIM PF02809.20 KKF93749.1 - 0.64 10.1 16.2 0.019 14.9 2.0 3.2 3 0 0 3 3 3 0 Ubiquitin interaction motif Asp PF00026.23 KKF93751.1 - 3e-05 23.6 0.1 0.00014 21.4 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease FtsJ PF01728.19 KKF93752.1 - 3.1e-53 180.5 0.0 4.8e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Peptidase_M20 PF01546.28 KKF93753.1 - 4.7e-22 78.7 0.0 2e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KKF93753.1 - 1.1e-16 60.9 7.5 0.013 16.3 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Peptidase_M28 PF04389.17 KKF93753.1 - 0.0004 20.1 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Nup160 PF11715.8 KKF93753.1 - 0.00046 19.0 0.4 0.57 8.8 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KKF93753.1 - 0.00065 19.9 0.3 1.7 9.0 0.0 3.9 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain M20_dimer PF07687.14 KKF93753.1 - 0.0043 16.9 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain eIF2A PF08662.11 KKF93753.1 - 0.14 12.0 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Asparaginase_2 PF01112.18 KKF93754.1 - 2.4e-46 158.2 0.2 2.2e-25 89.3 0.3 2.3 2 0 0 2 2 2 2 Asparaginase Tim17 PF02466.19 KKF93755.1 - 1.9e-32 111.9 7.9 2.6e-32 111.5 7.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PIR PF00399.19 KKF93756.1 - 0.0015 18.0 0.1 0.0042 16.6 0.1 1.8 1 0 0 1 1 1 1 Yeast PIR protein repeat Creatinase_N_2 PF16189.5 KKF93757.1 - 7.5e-47 159.4 0.0 1.1e-44 152.4 0.0 3.0 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KKF93757.1 - 9e-44 149.7 0.0 1.4e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KKF93757.1 - 3.5e-21 75.0 0.4 8.1e-21 73.9 0.1 1.9 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KKF93757.1 - 4.2e-20 72.8 0.0 1.8e-17 64.3 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain PAS_11 PF14598.6 KKF93757.1 - 0.062 13.4 0.0 20 5.4 0.0 2.9 2 0 0 2 2 2 0 PAS domain Requiem_N PF14051.6 KKF93758.1 - 0.065 13.5 0.1 0.097 12.9 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. CBFD_NFYB_HMF PF00808.23 KKF93759.1 - 1.1e-19 70.5 0.4 1.7e-19 69.8 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKF93759.1 - 1.9e-15 57.4 0.1 1.9e-15 57.4 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Pol_alpha_B_N PF08418.10 KKF93759.1 - 0.003 17.6 1.2 0.0041 17.1 1.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Med3 PF11593.8 KKF93759.1 - 0.019 14.2 15.7 0.028 13.6 15.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CENP-X PF09415.10 KKF93759.1 - 0.023 15.0 0.6 0.088 13.1 0.6 2.0 1 1 0 1 1 1 0 CENP-S associating Centromere protein X Rrn6 PF10214.9 KKF93759.1 - 2.6 6.4 7.9 3.3 6.1 7.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor ABC_tran PF00005.27 KKF93760.1 - 9.8e-33 113.6 0.0 2.1e-32 112.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KKF93760.1 - 1.7e-20 73.8 5.4 3e-20 73.0 4.3 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KKF93760.1 - 1.6e-05 24.4 1.0 5.2e-05 22.8 0.4 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKF93760.1 - 0.0066 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_10 PF12846.7 KKF93760.1 - 0.075 11.9 0.1 0.16 10.8 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain SbcCD_C PF13558.6 KKF93760.1 - 0.1 12.9 1.5 0.91 9.8 0.2 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KKF93760.1 - 0.18 11.6 0.1 0.42 10.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KKF93760.1 - 0.35 11.2 1.3 4.8 7.5 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain EnY2 PF10163.9 KKF93761.1 - 0.014 15.8 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Transcription factor e(y)2 AAA PF00004.29 KKF93762.1 - 9.9e-98 323.7 0.0 1.8e-47 161.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKF93762.1 - 9.7e-25 86.1 3.4 4.5e-14 52.0 0.6 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KKF93762.1 - 1.7e-16 60.1 0.1 6e-16 58.4 0.1 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KKF93762.1 - 4.5e-14 52.5 1.3 6.5e-06 26.0 0.0 3.9 6 1 0 6 6 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKF93762.1 - 7.6e-14 52.4 0.0 0.00014 22.3 0.0 4.8 3 2 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 KKF93762.1 - 3.8e-13 49.9 0.0 3.6e-07 30.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KKF93762.1 - 1.1e-11 45.1 0.0 3.7e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KKF93762.1 - 2.4e-11 43.8 0.3 5.8e-06 26.3 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKF93762.1 - 3.4e-09 37.1 0.5 0.029 14.7 0.1 4.1 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 KKF93762.1 - 3.7e-09 36.3 0.0 0.0012 18.1 0.0 2.8 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KKF93762.1 - 1.5e-07 31.5 0.0 0.0079 16.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain ATPase PF06745.13 KKF93762.1 - 3.8e-07 29.7 0.3 0.26 10.6 0.0 3.4 3 0 0 3 3 3 2 KaiC IstB_IS21 PF01695.17 KKF93762.1 - 4.8e-07 29.7 0.0 0.027 14.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KKF93762.1 - 5.1e-07 30.3 0.0 0.054 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KKF93762.1 - 5.8e-07 29.9 0.0 0.033 14.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase CDC48_2 PF02933.17 KKF93762.1 - 7.5e-07 28.8 0.1 1.6e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 KKF93762.1 - 8.9e-07 28.5 0.2 0.033 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 KKF93762.1 - 2.4e-06 27.4 0.1 2.7e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 KKF93762.1 - 2.9e-06 26.9 0.0 0.051 13.1 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KKF93762.1 - 9.7e-06 25.4 0.0 0.082 12.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 KKF93762.1 - 1.5e-05 25.3 0.0 0.3 11.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 KKF93762.1 - 1.7e-05 24.1 0.1 0.098 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KKF93762.1 - 1.9e-05 24.4 5.1 0.73 9.4 0.1 4.4 3 2 2 5 5 4 2 AAA domain Sigma54_activat PF00158.26 KKF93762.1 - 3.1e-05 23.8 0.0 0.29 10.8 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 KKF93762.1 - 9.1e-05 21.7 0.0 0.11 11.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ABC_tran PF00005.27 KKF93762.1 - 9.4e-05 22.9 0.0 0.67 10.5 0.0 3.6 3 1 0 3 3 2 1 ABC transporter TsaE PF02367.17 KKF93762.1 - 0.00011 22.1 0.0 0.66 10.0 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 KKF93762.1 - 0.00014 21.8 0.0 0.31 10.9 0.0 2.7 3 0 0 3 3 2 2 Bacterial dnaA protein PhoH PF02562.16 KKF93762.1 - 0.00016 21.2 0.3 0.45 9.9 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 KKF93762.1 - 0.00018 21.6 0.0 0.045 13.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 KKF93762.1 - 0.00029 21.3 0.1 0.57 10.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 KKF93762.1 - 0.00036 20.4 0.0 0.75 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KKF93762.1 - 0.00051 19.9 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KKF93762.1 - 0.00058 19.6 0.2 1.5 8.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KKF93762.1 - 0.00083 19.3 0.0 1.9 8.3 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KKF93762.1 - 0.00084 18.7 0.0 0.92 8.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KKF93762.1 - 0.0012 18.8 0.1 1.3 8.9 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.6 KKF93762.1 - 0.0018 18.6 0.8 6.7 7.0 0.1 3.7 3 1 1 4 4 3 0 AAA domain Sigma54_activ_2 PF14532.6 KKF93762.1 - 0.0032 17.6 0.0 0.55 10.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 KKF93762.1 - 0.0042 16.3 0.0 1.5 7.9 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 KKF93762.1 - 0.01 15.8 0.3 4.1 7.3 0.0 3.7 3 0 0 3 3 3 0 NTPase Viral_helicase1 PF01443.18 KKF93762.1 - 0.015 15.0 0.0 0.65 9.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IPT PF01745.16 KKF93762.1 - 0.023 14.1 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UFD1 PF03152.14 KKF93762.1 - 0.024 14.1 0.0 0.17 11.3 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 KAP_NTPase PF07693.14 KKF93762.1 - 0.034 13.4 1.9 1.1 8.4 0.0 3.4 3 2 1 5 5 4 0 KAP family P-loop domain Zeta_toxin PF06414.12 KKF93762.1 - 0.041 13.2 0.0 12 5.1 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin Zot PF05707.12 KKF93762.1 - 0.059 13.0 0.0 3.5 7.2 0.0 3.0 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 KKF93762.1 - 0.079 11.9 0.1 7.6 5.4 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region KTI12 PF08433.10 KKF93763.1 - 3e-65 220.4 0.0 4.6e-65 219.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF1771 PF08590.10 KKF93763.1 - 2.7e-23 82.1 10.3 5.3e-23 81.2 10.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KKF93763.1 - 1.8e-11 44.3 0.2 6.2e-11 42.5 0.2 2.0 1 0 0 1 1 1 1 Smr domain AAA_33 PF13671.6 KKF93763.1 - 0.00095 19.4 0.0 0.0032 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.18 KKF93763.1 - 0.0013 18.1 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.6 KKF93763.1 - 0.0092 16.5 0.1 0.1 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKF93763.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KKF93763.1 - 0.27 10.6 1.5 0.39 10.0 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) G-alpha PF00503.20 KKF93764.1 - 1.3e-123 412.7 3.4 1.5e-123 412.5 3.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KKF93764.1 - 2.6e-15 56.3 1.4 3e-10 39.8 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KKF93764.1 - 5.4e-05 22.9 0.1 0.00023 20.9 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KKF93764.1 - 0.0024 17.3 3.3 0.12 11.8 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KKF93764.1 - 0.02 14.7 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KKF93764.1 - 0.024 14.9 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 KKF93764.1 - 0.032 13.3 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 KKF93764.1 - 0.098 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KKF93764.1 - 0.13 12.3 0.1 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKF93764.1 - 0.15 11.6 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF3716 PF12511.8 KKF93765.1 - 1.9e-16 59.8 10.4 3.1e-16 59.2 10.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Zip PF02535.22 KKF93765.1 - 1.5 8.0 6.6 2.6 7.2 6.6 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KKF93765.1 - 4.6 5.9 7.3 6.8 5.3 7.3 1.4 1 0 0 1 1 1 0 Presenilin Synuclein PF01387.17 KKF93765.1 - 5.6 7.2 7.0 3.7 7.7 4.0 2.2 1 1 1 2 2 2 0 Synuclein Lin-8 PF03353.15 KKF93765.1 - 8.7 5.8 11.6 17 4.9 11.6 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ABC_tran PF00005.27 KKF93766.1 - 1.5e-39 135.7 0.0 1.1e-14 55.1 0.0 3.8 3 1 0 3 3 3 3 ABC transporter ABC_membrane PF00664.23 KKF93766.1 - 1.4e-33 116.7 22.7 1.3e-19 70.9 14.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KKF93766.1 - 9.3e-14 51.4 2.0 0.00042 19.8 0.0 4.6 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKF93766.1 - 5.4e-07 29.3 2.9 0.0024 17.6 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KKF93766.1 - 2.1e-06 28.0 0.2 0.14 12.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KKF93766.1 - 5e-06 27.0 0.0 0.18 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KKF93766.1 - 3.7e-05 23.4 0.1 0.00082 19.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KKF93766.1 - 5.4e-05 23.2 0.0 0.76 9.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKF93766.1 - 0.00011 22.8 0.0 0.16 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKF93766.1 - 0.00014 21.8 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKF93766.1 - 0.00026 21.0 0.0 0.3 11.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 KKF93766.1 - 0.0007 20.0 0.1 0.62 10.5 0.0 4.0 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KKF93766.1 - 0.00087 18.4 0.6 0.053 12.6 0.0 3.2 4 0 0 4 4 4 1 Type II/IV secretion system protein RNA_helicase PF00910.22 KKF93766.1 - 0.0022 18.4 0.1 4.6 7.7 0.0 3.2 3 0 0 3 3 3 1 RNA helicase DUF87 PF01935.17 KKF93766.1 - 0.0024 18.0 2.0 0.14 12.2 0.3 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain NACHT PF05729.12 KKF93766.1 - 0.0028 17.6 0.0 2.3 8.1 0.0 2.9 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 KKF93766.1 - 0.0044 16.4 0.7 0.15 11.4 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 KKF93766.1 - 0.0077 15.8 0.1 1.9 8.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase PF06745.13 KKF93766.1 - 0.01 15.2 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 KKF93766.1 - 0.022 14.7 0.0 0.91 9.4 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 KKF93766.1 - 0.042 14.1 0.2 12 6.2 0.0 3.0 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DUF2075 PF09848.9 KKF93766.1 - 0.055 12.7 0.1 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KKF93766.1 - 0.079 12.1 0.2 13 4.9 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 KKF93766.1 - 0.14 12.2 0.1 19 5.2 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 KKF93766.1 - 0.15 11.3 0.2 9.3 5.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 KKF93766.1 - 0.22 11.4 0.2 2.3 8.1 0.1 2.3 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.20 KKF93766.1 - 0.23 11.3 0.5 0.86 9.5 0.1 2.2 3 0 0 3 3 3 0 Adenylylsulphate kinase PalH PF08733.10 KKF93767.1 - 2.1e-109 365.5 0.3 3.1e-109 365.0 0.3 1.2 1 0 0 1 1 1 1 PalH/RIM21 CAAD PF14159.6 KKF93767.1 - 0.14 12.0 0.1 0.5 10.2 0.1 1.9 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase YjeF_N PF03853.15 KKF93769.1 - 4.8e-34 117.7 0.0 7e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KKF93769.1 - 6.4e-08 33.4 0.8 6.4e-08 33.4 0.8 2.2 2 0 0 2 2 2 1 FDF domain TFIIA PF03153.13 KKF93769.1 - 0.13 12.3 7.1 0.1 12.6 6.0 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S19 PF00203.21 KKF93770.1 - 6.1e-29 99.7 0.0 7.1e-29 99.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 KKF93771.1 - 8.3e-25 86.5 0.2 1.3e-24 85.9 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KKF93771.1 - 0.048 14.2 2.6 0.1 13.1 2.6 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 FDF PF09532.10 KKF93772.1 - 5e-15 56.3 9.3 5e-15 56.3 9.3 2.6 3 1 0 3 3 3 1 FDF domain API5 PF05918.11 KKF93772.1 - 0.65 8.7 3.7 1.3 7.8 3.7 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Mitofilin PF09731.9 KKF93772.1 - 3.9 6.2 9.2 5.2 5.8 9.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MGC-24 PF05283.11 KKF93773.1 - 0.016 15.6 5.3 0.022 15.2 5.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 KKF93773.1 - 3.5 5.7 8.1 3.7 5.6 8.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pyr_redox_2 PF07992.14 KKF93774.1 - 5.7e-58 196.5 0.8 7.9e-58 196.0 0.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKF93774.1 - 5.1e-35 120.1 0.6 1.4e-34 118.6 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KKF93774.1 - 1.8e-19 70.1 5.6 5.7e-19 68.4 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKF93774.1 - 1.4e-17 64.0 0.3 1.9e-17 63.5 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKF93774.1 - 3.8e-05 23.0 0.1 0.0018 17.5 0.0 2.3 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KKF93774.1 - 0.00057 19.4 0.1 0.00079 18.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKF93774.1 - 0.0028 17.0 1.1 0.0068 15.7 0.5 1.9 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 KKF93774.1 - 0.0044 16.9 0.0 0.0044 16.9 0.0 2.7 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KKF93774.1 - 0.0065 15.6 0.7 0.08 12.0 0.7 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KKF93774.1 - 0.0065 15.2 2.9 0.91 8.1 1.9 3.0 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KKF93774.1 - 0.017 14.4 0.4 6 6.1 0.4 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KKF93774.1 - 0.022 14.1 1.3 0.026 13.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KKF93774.1 - 0.069 12.4 3.1 7.6 5.7 1.5 2.6 2 1 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 KKF93774.1 - 0.7 8.9 6.1 1.7 7.7 2.5 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KKF93774.1 - 7.4 6.9 6.2 1.5 9.1 1.9 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HA2 PF04408.23 KKF93775.1 - 4.9e-15 55.7 0.2 1.6e-14 54.1 0.2 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKF93775.1 - 1.8e-14 54.0 0.0 4.3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KKF93775.1 - 1.8e-13 50.6 0.0 4.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KKF93775.1 - 0.077 12.8 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase SKG6 PF08693.10 KKF93777.1 - 1e-05 24.8 4.4 2.9e-05 23.4 4.4 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.14 KKF93777.1 - 0.095 12.8 0.8 0.14 12.2 0.8 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TFIIA PF03153.13 KKF93777.1 - 0.14 12.2 5.0 0.18 11.7 5.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SCF PF02404.15 KKF93777.1 - 0.58 9.5 1.7 0.52 9.6 0.2 1.6 1 1 1 2 2 2 0 Stem cell factor COesterase PF00135.28 KKF93778.1 - 8.9e-44 150.2 0.0 1.1e-43 149.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKF93778.1 - 2.5e-07 30.8 0.4 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ferric_reduct PF01794.19 KKF93779.1 - 6.8e-18 65.0 9.9 6.8e-18 65.0 9.9 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component YfhO PF09586.10 KKF93780.1 - 0.12 10.6 1.3 0.13 10.4 1.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Bromo_TP PF07524.13 KKF93781.1 - 9.4e-11 41.6 0.0 2.3e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Bromodomain PF00439.25 KKF93781.1 - 1.1e-09 38.3 0.3 2.8e-09 36.9 0.1 1.9 2 0 0 2 2 2 1 Bromodomain Bromo_TP_like PF17027.5 KKF93781.1 - 0.036 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Histone-fold protein PA PF02225.22 KKF93781.1 - 0.091 12.8 0.4 0.22 11.6 0.4 1.6 1 0 0 1 1 1 0 PA domain CheZ PF04344.13 KKF93781.1 - 0.71 9.7 9.0 0.057 13.3 1.8 2.6 2 1 1 3 3 3 0 Chemotaxis phosphatase, CheZ SHMT PF00464.19 KKF93782.1 - 1.5e-208 692.2 0.0 1.8e-208 692.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KKF93782.1 - 2.7e-05 23.5 0.0 4.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKF93782.1 - 0.039 13.2 0.0 0.056 12.7 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Asp PF00026.23 KKF93783.1 - 5e-112 374.4 0.0 6.7e-112 374.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKF93783.1 - 1.6e-16 61.1 0.6 1.2e-14 54.9 0.6 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KKF93783.1 - 2.7e-05 24.0 0.0 0.00084 19.1 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KKF93783.1 - 0.00019 22.0 0.1 1.3 9.7 0.0 3.3 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KKF93783.1 - 0.0032 18.0 0.0 3 8.5 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TMEM215 PF15746.5 KKF93784.1 - 0.03 13.8 0.3 0.42 10.0 0.1 2.3 2 0 0 2 2 2 0 TMEM215 family DUF155 PF02582.14 KKF93785.1 - 1.9e-38 132.3 0.0 3.1e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Drc1-Sld2 PF11719.8 KKF93787.1 - 8.8e-61 206.8 30.2 8.8e-61 206.8 30.2 2.8 2 1 0 2 2 2 1 DNA replication and checkpoint protein DASH_Spc34 PF08657.10 KKF93787.1 - 1.4e-53 182.3 1.2 2.8e-26 92.9 0.2 2.6 1 1 1 2 2 2 2 DASH complex subunit Spc34 DUF4636 PF15468.6 KKF93787.1 - 0.15 11.8 4.7 0.29 10.8 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) UPF0242 PF06785.11 KKF93787.1 - 0.66 10.1 8.2 1.3 9.0 8.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TFIID_20kDa PF03847.13 KKF93789.1 - 5.1e-17 62.1 0.0 8.8e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Rpn3_C PF08375.11 KKF93790.1 - 2.5e-25 88.7 2.3 7.4e-25 87.2 2.3 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KKF93790.1 - 1.7e-19 70.2 0.2 1.1e-18 67.6 0.1 2.4 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 KKF93790.1 - 0.022 14.8 0.8 0.071 13.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MOZ_SAS PF01853.18 KKF93791.1 - 2e-56 190.5 0.0 3.3e-56 189.8 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KKF93791.1 - 0.00016 21.2 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_1 PF00583.25 KKF93791.1 - 0.042 14.1 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKF93791.1 - 0.066 13.6 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TFIIB PF00382.19 KKF93793.1 - 2.9e-31 107.3 0.5 1.6e-19 69.7 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KKF93793.1 - 3.9e-12 45.5 2.0 7.3e-12 44.6 2.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 KKF93793.1 - 0.00023 21.2 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain zf-ribbon_3 PF13248.6 KKF93793.1 - 0.063 12.7 0.9 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Sigma70_r4 PF04545.16 KKF93793.1 - 0.2 11.2 0.0 0.71 9.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Clr5 PF14420.6 KKF93794.1 - 2.2e-16 59.8 0.2 5.2e-16 58.6 0.2 1.6 1 0 0 1 1 1 1 Clr5 domain Pex14_N PF04695.13 KKF93794.1 - 0.24 12.0 0.1 0.24 12.0 0.1 4.1 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TRP PF06011.12 KKF93795.1 - 5e-114 381.3 21.9 4.7e-68 229.9 8.4 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KKF93795.1 - 1.5e-33 116.1 2.4 2.5e-33 115.4 2.4 1.4 1 0 0 1 1 1 1 ML-like domain Abhydrolase_6 PF12697.7 KKF93795.1 - 7.1e-22 79.1 9.0 9.6e-22 78.7 5.4 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKF93795.1 - 1.5e-09 37.9 0.4 6e-06 26.1 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKF93795.1 - 6.3e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 E1_DerP2_DerF2 PF02221.15 KKF93795.1 - 0.006 17.0 0.7 0.011 16.1 0.7 1.4 1 0 0 1 1 1 1 ML domain Thioesterase PF00975.20 KKF93795.1 - 0.15 12.2 0.2 0.4 10.7 0.2 1.7 1 1 0 1 1 1 0 Thioesterase domain ODV-E18 PF10717.9 KKF93795.1 - 3.3 7.7 5.4 0.56 10.1 0.4 2.4 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 SCIMP PF15050.6 KKF93795.1 - 5.8 7.4 6.8 1.5e+02 2.8 4.8 3.2 3 0 0 3 3 3 0 SCIMP protein Cellulase PF00150.18 KKF93796.1 - 1.6e-25 90.2 0.6 4.6e-24 85.3 0.6 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) 7tm_2 PF00002.24 KKF93797.1 - 8.7e-08 31.7 12.9 8.7e-08 31.7 12.9 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srv PF10323.9 KKF93797.1 - 0.002 17.6 2.4 0.0044 16.4 2.4 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Dicty_CAR PF05462.11 KKF93797.1 - 0.021 13.9 12.3 0.051 12.7 10.7 2.0 1 1 1 2 2 2 0 Slime mold cyclic AMP receptor zf-Tim10_DDP PF02953.15 KKF93798.1 - 1.3e-12 47.1 4.8 1.7e-12 46.8 4.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.9 KKF93798.1 - 0.34 11.0 0.2 0.34 11.0 0.2 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase PG_binding_1 PF01471.18 KKF93799.1 - 3.8e-05 23.8 0.0 0.0031 17.7 0.0 3.3 4 0 0 4 4 4 1 Putative peptidoglycan binding domain Tropomyosin_1 PF12718.7 KKF93799.1 - 0.00081 19.6 1.3 0.0022 18.2 0.5 2.1 1 1 0 2 2 2 1 Tropomyosin like SlyX PF04102.12 KKF93799.1 - 0.071 13.7 1.4 0.28 11.8 1.4 2.1 1 0 0 1 1 1 0 SlyX Laminin_II PF06009.12 KKF93799.1 - 0.1 12.6 1.1 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 Laminin Domain II XhlA PF10779.9 KKF93799.1 - 0.12 12.6 0.5 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DUF5082 PF16888.5 KKF93799.1 - 0.12 12.7 0.1 0.28 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) ADIP PF11559.8 KKF93799.1 - 0.13 12.3 0.1 0.41 10.7 0.1 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PsbI PF02532.14 KKF93800.1 - 0.28 11.2 0.2 0.28 11.2 0.2 3.3 4 1 0 4 4 4 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Glyco_tranf_2_3 PF13641.6 KKF93801.1 - 3.3e-26 92.6 0.0 4.1e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KKF93801.1 - 7.4e-08 32.1 0.0 1.5e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KKF93801.1 - 8.7e-08 32.2 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Gp45_2 PF17470.2 KKF93801.1 - 0.001 19.0 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 Phage gene product 45.2 PNMA PF14893.6 KKF93802.1 - 0.00056 19.4 1.9 0.0007 19.1 1.9 1.1 1 0 0 1 1 1 1 PNMA ART-PolyVal PF18760.1 KKF93802.1 - 0.01 16.9 0.5 0.021 15.9 0.5 1.4 1 0 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins Methyltransf_33 PF10017.9 KKF93802.1 - 0.11 11.6 2.6 0.18 10.9 2.6 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent GWT1 PF06423.12 KKF93804.1 - 3.3e-24 85.7 1.4 6.7e-24 84.7 0.2 2.1 2 1 0 2 2 2 1 GWT1 DUF4818 PF16089.5 KKF93804.1 - 0.21 12.0 3.3 0.23 11.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4818) Pkinase PF00069.25 KKF93805.1 - 2e-65 220.8 0.0 3.9e-65 219.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF93805.1 - 3.7e-37 128.0 0.0 4.7e-31 108.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KKF93805.1 - 1.4e-06 27.8 0.0 0.00021 20.7 0.0 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KKF93805.1 - 0.00065 19.7 0.1 0.006 16.5 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKF93805.1 - 0.0063 15.5 0.2 0.011 14.7 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKF93805.1 - 0.033 13.5 0.1 0.066 12.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_Mu_Gp45 PF06890.12 KKF93805.1 - 0.093 12.5 1.1 0.39 10.5 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein RIO1 PF01163.22 KKF93805.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family HSP20 PF00011.21 KKF93806.1 - 1.8e-13 50.5 0.1 1.1e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KKF93806.1 - 0.0015 18.1 0.0 0.049 13.2 0.0 2.6 3 0 0 3 3 3 1 HSP20-like domain found in ArsA ATF7IP_BD PF16788.5 KKF93806.1 - 4.6 7.3 7.8 6.9 6.7 7.8 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain SPRY PF00622.28 KKF93807.1 - 2.2e-06 27.8 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 SPRY domain FAD-oxidase_C PF02913.19 KKF93808.1 - 3.7e-60 203.6 0.1 5.3e-60 203.2 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KKF93808.1 - 6.7e-37 126.3 0.0 1.3e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain E1-E2_ATPase PF00122.20 KKF93809.1 - 9.2e-32 110.0 9.0 6e-28 97.6 0.2 3.3 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKF93809.1 - 8.2e-30 103.9 1.3 8.2e-30 103.9 1.3 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KKF93809.1 - 3e-18 66.9 0.0 1.1e-13 52.0 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKF93809.1 - 6e-18 64.7 0.0 1.7e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KKF93809.1 - 4.9e-11 42.1 0.0 1.4e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKF93809.1 - 3.1e-06 27.1 0.7 6.4e-05 22.8 0.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TAF4 PF05236.14 KKF93810.1 - 4.6e-25 88.9 10.8 6.8e-21 75.2 0.6 3.1 3 0 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family Activator_LAG-3 PF11498.8 KKF93810.1 - 0.0056 15.7 34.7 0.0095 15.0 34.7 1.3 1 0 0 1 1 1 1 Transcriptional activator LAG-3 DDHD PF02862.17 KKF93810.1 - 0.025 14.7 3.9 0.31 11.2 0.9 2.2 2 0 0 2 2 2 0 DDHD domain FliP PF00813.20 KKF93810.1 - 1 9.2 5.3 1.7 8.5 5.3 1.2 1 0 0 1 1 1 0 FliP family Neur_chan_memb PF02932.16 KKF93810.1 - 6.4 6.8 9.3 3.5 7.6 4.3 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CPSF73-100_C PF11718.8 KKF93811.1 - 7.1e-77 257.8 0.2 9.6e-77 257.4 0.2 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KKF93811.1 - 8.4e-31 106.5 0.0 2.8e-30 104.8 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KKF93811.1 - 1e-12 47.8 0.1 2.2e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain DASH_Dad2 PF08654.10 KKF93812.1 - 8e-30 103.2 2.1 1.5e-29 102.3 2.1 1.5 1 1 0 1 1 1 1 DASH complex subunit Dad2 DHC_N2 PF08393.13 KKF93812.1 - 0.064 12.4 0.0 0.065 12.3 0.0 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Shugoshin_N PF07558.11 KKF93813.1 - 4.7e-15 55.2 8.0 1.2e-14 53.9 8.0 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KKF93813.1 - 8.2e-11 41.5 7.3 8.2e-11 41.5 7.3 3.2 4 0 0 4 4 4 1 Shugoshin C terminus Metallophos_2 PF12850.7 KKF93814.1 - 6.2e-09 36.3 0.0 7.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.19 KKF93815.1 - 4.8e-29 101.5 0.0 6.2e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V CRM1_C PF08767.11 KKF93816.1 - 1.6e-134 448.1 2.1 1.6e-134 448.1 2.1 3.0 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KKF93816.1 - 2e-40 138.3 7.3 2e-40 138.3 7.3 3.6 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KKF93816.1 - 3.7e-32 109.8 4.8 1.1e-31 108.3 4.8 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KKF93816.1 - 9.9e-28 96.0 1.2 9.9e-28 96.0 1.2 2.9 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KKF93816.1 - 6.9e-19 67.1 1.2 1.9e-18 65.7 1.2 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KKF93816.1 - 7.9e-14 51.3 0.4 3.1e-13 49.4 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KKF93816.1 - 0.043 13.7 5.5 0.29 11.0 0.1 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) BID PF06393.11 KKF93816.1 - 0.08 12.5 0.3 0.26 10.8 0.1 2.0 2 0 0 2 2 2 0 BH3 interacting domain (BID) Pre-PUA PF17832.1 KKF93816.1 - 0.11 13.2 0.0 0.59 10.9 0.0 2.3 2 0 0 2 2 1 0 Pre-PUA-like domain Prolamin_like PF05617.11 KKF93816.1 - 0.84 9.9 3.6 2.2 8.5 0.1 3.2 3 0 0 3 3 3 0 Prolamin-like Vac14_Fab1_bd PF12755.7 KKF93816.1 - 1.1 9.9 5.2 3 8.5 0.0 4.4 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Ecl1 PF12855.7 KKF93817.1 - 4.8e-15 57.2 31.0 5.8e-15 56.9 31.0 1.0 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins Nup54_57_C PF18570.1 KKF93817.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain Rib PF08428.10 KKF93818.1 - 0.0025 17.8 0.0 0.0071 16.3 0.0 1.8 2 0 0 2 2 2 1 Rib/alpha-like repeat Cas_csx3 PF09620.10 KKF93818.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Cu_bind_like PF02298.17 KKF93818.1 - 0.099 12.7 0.1 0.16 12.0 0.1 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain Cu_bind_like PF02298.17 KKF93819.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain Cas_csx3 PF09620.10 KKF93819.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Cupredoxin_1 PF13473.6 KKF93819.1 - 0.02 15.0 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain Cas_csx3 PF09620.10 KKF93820.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Cu_bind_like PF02298.17 KKF93820.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 Plastocyanin-like domain RVT_2 PF07727.14 KKF93822.1 - 7.8e-09 35.5 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.6 KKF93822.1 - 0.00034 20.4 0.9 0.00034 20.4 0.9 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_3 PF13456.6 KKF93822.1 - 0.00055 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like rve PF00665.26 KKF93822.1 - 0.00082 19.5 0.0 0.0032 17.6 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Cupredoxin_1 PF13473.6 KKF93822.1 - 0.014 15.5 0.1 0.032 14.4 0.1 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain zf-CCHC_2 PF13696.6 KKF93822.1 - 0.32 10.9 1.4 0.86 9.5 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Cupredoxin_1 PF13473.6 KKF93823.1 - 0.0078 16.3 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Cupredoxin-like domain Cupredoxin_1 PF13473.6 KKF93824.1 - 0.018 15.2 0.1 0.036 14.2 0.1 1.5 1 1 0 1 1 1 0 Cupredoxin-like domain Brix PF04427.18 KKF93825.1 - 2.2e-49 168.2 0.0 3.3e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Brix domain DUF1168 PF06658.12 KKF93825.1 - 0.0044 16.8 6.9 0.0044 16.8 6.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) Kinesin PF00225.23 KKF93827.1 - 6.9e-49 166.6 0.0 1.4e-48 165.6 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKF93827.1 - 0.00012 22.1 0.0 0.036 14.0 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding STAC2_u1 PF16664.5 KKF93827.1 - 0.079 13.4 0.7 0.45 11.0 0.7 2.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF5094 PF17015.5 KKF93827.1 - 0.2 11.8 2.9 0.32 11.1 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) UPF0184 PF03670.13 KKF93827.1 - 0.24 11.8 2.5 35 4.9 2.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Peptidase_S24 PF00717.23 KKF93828.1 - 2.7e-07 30.4 0.1 4e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like BTB PF00651.31 KKF93829.1 - 1.7e-06 28.2 0.0 5.7e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain TFIIB PF00382.19 KKF93830.1 - 1.1e-36 124.6 0.8 4.4e-20 71.5 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KKF93830.1 - 7.1e-25 87.3 0.2 7.1e-25 87.3 0.2 2.9 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KKF93830.1 - 3.7e-05 23.5 0.3 0.13 12.0 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.12 KKF93830.1 - 0.0051 16.3 1.6 0.015 14.8 1.6 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Abhydrolase_1 PF00561.20 KKF93831.1 - 5e-10 39.4 0.0 2.2e-08 34.1 0.0 2.7 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKF93831.1 - 1.6e-05 24.3 0.0 0.0039 16.5 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF3808 PF10300.9 KKF93832.1 - 1.2e-123 413.3 0.3 1.5e-123 413.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF1039 PF06287.11 KKF93832.1 - 0.37 11.2 0.1 0.37 11.2 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1039) TPR_16 PF13432.6 KKF93832.1 - 1.4 9.6 7.5 7.9 7.2 0.0 4.1 3 2 0 3 3 3 0 Tetratricopeptide repeat DSS1_SEM1 PF05160.13 KKF93833.1 - 1.5e-23 82.6 11.3 1.8e-23 82.4 11.3 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.12 KKF93833.1 - 0.03 14.0 2.4 0.033 13.9 2.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2947 PF11163.8 KKF93833.1 - 0.047 13.5 1.3 0.052 13.4 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) PGK PF00162.19 KKF93834.1 - 4.8e-142 473.4 1.2 9.1e-94 314.5 0.6 2.0 2 0 0 2 2 2 2 Phosphoglycerate kinase PA PF02225.22 KKF93834.1 - 0.0013 18.7 0.0 0.11 12.6 0.0 3.1 3 1 0 3 3 3 1 PA domain Mpv17_PMP22 PF04117.12 KKF93835.1 - 3.6e-15 55.9 0.7 6.5e-15 55.1 0.1 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Glyco_transf_21 PF13506.6 KKF93836.1 - 2.2e-09 37.0 0.0 0.0015 18.1 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KKF93836.1 - 0.0018 18.2 0.0 0.025 14.4 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 MFS_1 PF07690.16 KKF93837.1 - 2.9e-14 52.8 13.6 3.4e-14 52.5 13.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 KKF93837.1 - 0.0036 15.8 0.6 0.0043 15.5 0.6 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.24 KKF93837.1 - 0.026 13.4 5.2 0.05 12.5 5.2 1.4 1 0 0 1 1 1 0 Sugar (and other) transporter FmiP_Thoc5 PF09766.9 KKF93837.1 - 0.22 10.8 0.7 0.29 10.4 0.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 BCS1_N PF08740.11 KKF93838.1 - 3.1e-30 105.5 0.3 3.1e-30 105.5 0.3 2.0 2 0 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 KKF93838.1 - 5.3e-16 59.3 0.0 1.8e-15 57.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKF93838.1 - 0.00018 21.3 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKF93838.1 - 0.016 15.2 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKF93838.1 - 0.018 15.5 0.0 0.072 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKF93838.1 - 0.032 14.6 0.8 0.16 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.6 KKF93838.1 - 0.037 14.3 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain VioE PF18234.1 KKF93838.1 - 0.09 12.9 0.6 4 7.5 0.5 2.3 2 0 0 2 2 2 0 Violacein biosynthetic enzyme VioE IPT PF01745.16 KKF93838.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase AAA_11 PF13086.6 KKF93838.1 - 0.57 9.9 0.0 0.57 9.9 0.0 3.5 4 0 0 4 4 4 0 AAA domain Hydin_ADK PF17213.3 KKF93838.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.4 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Ly49 PF08391.10 KKF93838.1 - 5.8 7.3 5.9 14 6.1 5.9 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region BROMI PF14961.6 KKF93838.1 - 8.4 3.7 6.7 12 3.2 6.7 1.1 1 0 0 1 1 1 0 Broad-minded protein Dioxygenase_C PF00775.21 KKF93839.1 - 2.2e-05 24.0 0.0 4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase ER-remodelling PF14755.6 KKF93839.1 - 0.05 13.9 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Intracellular membrane remodeller NMT1 PF09084.11 KKF93840.1 - 0.059 13.3 0.0 0.28 11.1 0.0 1.9 1 1 1 2 2 2 0 NMT1/THI5 like NMT1_2 PF13379.6 KKF93840.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 NMT1-like family TPT PF03151.16 KKF93842.1 - 9.2e-20 71.2 13.9 1.4e-19 70.5 13.9 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KKF93842.1 - 0.003 17.8 4.3 0.003 17.8 4.3 2.8 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 KKF93842.1 - 0.24 10.6 19.7 1.2 8.2 19.7 2.0 1 1 0 1 1 1 0 UAA transporter family TMEM234 PF10639.9 KKF93842.1 - 9 6.4 12.4 0.19 11.8 3.5 2.5 3 0 0 3 3 3 0 Putative transmembrane family 234 Ras PF00071.22 KKF93843.1 - 2.5e-31 108.5 0.1 3.5e-31 108.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF93843.1 - 6e-24 84.6 0.1 1.4e-23 83.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF93843.1 - 1.6e-06 27.7 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKF93843.1 - 0.00031 20.2 0.1 0.00048 19.5 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Zip PF02535.22 KKF93843.1 - 0.046 12.9 2.0 0.047 12.9 2.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DLIC PF05783.11 KKF93843.1 - 0.1 11.4 6.7 0.23 10.2 0.0 2.9 1 1 2 3 3 3 0 Dynein light intermediate chain (DLIC) Macoilin PF09726.9 KKF93843.1 - 0.89 8.0 15.5 1.2 7.6 15.5 1.1 1 0 0 1 1 1 0 Macoilin family Neur_chan_memb PF02932.16 KKF93843.1 - 1.5 8.8 4.9 2.7 8.0 4.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 KKF93843.1 - 1.9 8.4 29.6 2.4 8.1 29.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SMYLE_N PF18615.1 KKF93843.1 - 2.2 7.7 7.0 3.2 7.2 7.0 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Suf PF05843.14 KKF93843.1 - 3.2 7.7 8.6 5.4 6.9 8.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Lin-8 PF03353.15 KKF93843.1 - 3.6 7.1 10.3 6.7 6.2 10.3 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1387 PF07139.11 KKF93843.1 - 4.2 7.0 10.0 6.4 6.4 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) GCV_H PF01597.19 KKF93844.1 - 3.7e-36 123.7 0.2 4.4e-36 123.4 0.2 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Porphobil_deam PF01379.20 KKF93845.1 - 2.8e-76 255.6 0.0 7e-76 254.3 0.0 1.6 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KKF93845.1 - 9.5e-18 64.4 0.1 1.9e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain PNTB PF02233.16 KKF93846.1 - 1.4e-157 525.3 20.9 2.6e-157 524.5 20.9 1.4 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KKF93846.1 - 2.6e-70 236.1 0.4 2.6e-70 236.1 0.4 2.3 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KKF93846.1 - 1.6e-45 154.8 0.3 6.1e-45 152.9 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KKF93846.1 - 3.4e-10 40.3 0.2 3.4e-10 40.3 0.2 5.1 4 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch ADH_zinc_N PF00107.26 KKF93846.1 - 0.017 15.1 1.7 0.042 13.8 0.3 2.5 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KKF93846.1 - 0.029 13.6 0.2 0.072 12.3 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KKF93846.1 - 0.032 13.6 0.3 0.63 9.4 0.0 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KKF93846.1 - 0.055 12.6 0.4 0.083 12.0 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KKF93846.1 - 0.072 13.3 1.2 0.31 11.3 1.2 2.2 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NDUFA12 PF05071.16 KKF93847.1 - 2.7e-32 111.5 2.4 3.2e-32 111.2 2.4 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 KKF93848.1 - 3.3e-15 56.2 0.0 8.5e-07 28.9 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KKF93848.1 - 8.5e-08 32.1 1.5 0.0014 18.7 0.2 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif PBP PF01161.20 KKF93849.1 - 6.5e-07 29.7 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.22 KKF93850.1 - 1.3e-49 168.5 0.0 1.6e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family UBA_4 PF14555.6 KKF93850.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Rep_fac-A_3 PF08661.11 KKF93851.1 - 9.7e-21 74.1 0.0 1e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF4184 PF13803.6 KKF93851.1 - 0.11 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) VP9 PF09625.10 KKF93851.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 VP9 protein CBS PF00571.28 KKF93852.1 - 6e-26 90.7 9.6 1.6e-10 41.3 0.5 4.2 4 0 0 4 4 4 3 CBS domain Arm PF00514.23 KKF93853.1 - 1.8e-75 246.9 28.3 1.4e-13 50.3 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKF93853.1 - 1.1e-19 70.5 10.4 9.8e-05 22.8 0.1 7.6 7 1 1 8 8 7 4 HEAT-like repeat HEAT_2 PF13646.6 KKF93853.1 - 9e-17 61.3 6.1 1.3e-05 25.5 0.2 7.3 4 2 3 7 7 7 4 HEAT repeats HEAT PF02985.22 KKF93853.1 - 2.4e-13 49.1 10.9 0.24 11.8 0.2 9.0 9 0 0 9 9 9 3 HEAT repeat Adaptin_N PF01602.20 KKF93853.1 - 8.5e-11 41.1 7.7 3.4e-05 22.6 0.6 3.1 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 KKF93853.1 - 7.1e-10 38.8 5.0 0.00025 20.6 2.0 2.9 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.12 KKF93853.1 - 1.2e-09 36.9 0.4 3.8e-09 35.3 0.2 1.6 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KKF93853.1 - 5.9e-07 29.1 2.9 0.0006 19.2 1.7 3.4 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 KKF93853.1 - 4.5e-06 26.8 0.5 2 8.6 0.2 5.2 3 1 3 6 6 6 2 V-ATPase subunit H Cnd1 PF12717.7 KKF93853.1 - 8.8e-06 25.8 8.8 0.022 14.8 0.2 5.3 1 1 4 7 7 7 3 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KKF93853.1 - 4.4e-05 23.5 5.4 2.3 8.1 0.0 4.4 1 1 4 5 5 5 2 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 KKF93853.1 - 0.0019 18.7 2.7 20 6.2 0.3 6.5 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 KKF93853.1 - 0.0029 17.6 6.2 3 7.9 0.2 4.8 3 2 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 KKF93853.1 - 0.0031 17.5 1.5 0.77 9.7 0.2 3.5 2 1 2 4 4 4 1 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 KKF93853.1 - 0.12 13.0 0.1 5.3 7.7 0.0 3.4 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region DrsE PF02635.15 KKF93853.1 - 0.12 12.7 0.2 0.69 10.3 0.1 2.3 3 0 0 3 3 2 0 DsrE/DsrF-like family Peptidase_S24 PF00717.23 KKF93854.1 - 1.2e-07 31.6 0.1 2e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KKF93854.1 - 0.00011 22.0 0.0 0.0058 16.4 0.0 2.7 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 IF3_C PF00707.22 KKF93855.1 - 6e-07 29.3 0.3 1.3e-05 25.1 0.2 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KKF93855.1 - 6e-05 22.8 8.6 0.0023 17.7 2.7 3.7 2 2 2 4 4 4 3 Mitochondrial translation initiation factor IF-2B PF01008.17 KKF93856.1 - 2.2e-43 148.5 0.3 6.4e-43 147.0 0.3 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family COMPASS-Shg1 PF05205.12 KKF93858.1 - 2.2e-22 79.7 0.1 2.2e-22 79.7 0.1 2.3 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 ICA69 PF04629.14 KKF93858.1 - 0.58 10.4 12.0 0.98 9.7 12.0 1.4 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain GAGA_bind PF06217.12 KKF93858.1 - 3.6 7.8 12.3 6.1 7.0 12.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family TIP120 PF08623.10 KKF93860.1 - 3e-62 209.3 2.9 5.2e-61 205.3 0.1 3.5 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KKF93860.1 - 2.1e-12 47.2 3.6 0.43 11.0 0.0 6.7 4 2 3 7 7 7 4 HEAT repeats HEAT_EZ PF13513.6 KKF93860.1 - 2.9e-11 43.6 6.9 0.31 11.6 0.0 8.8 8 1 1 9 9 9 3 HEAT-like repeat HEAT PF02985.22 KKF93860.1 - 9.9e-10 37.8 11.8 0.37 11.2 0.0 9.2 10 0 0 10 10 10 3 HEAT repeat CLASP_N PF12348.8 KKF93860.1 - 2.8e-05 23.8 2.3 0.03 13.9 0.3 3.5 3 0 0 3 3 3 2 CLASP N terminal Peptidase_M50B PF13398.6 KKF93861.1 - 7.4e-57 192.2 20.6 9.1e-57 191.9 20.6 1.1 1 0 0 1 1 1 1 Peptidase M50B-like YjcB PF15940.5 KKF93861.1 - 0.014 15.6 2.1 0.063 13.5 2.0 2.3 1 1 0 1 1 1 0 Family of unknown function Peptidase_M50 PF02163.22 KKF93861.1 - 0.11 11.7 0.9 0.18 11.0 0.3 1.6 2 0 0 2 2 2 0 Peptidase family M50 YlaC PF10777.9 KKF93861.1 - 0.12 12.2 0.4 0.12 12.2 0.4 1.9 2 1 0 2 2 2 0 Inner membrane protein YlaC PhoLip_ATPase_C PF16212.5 KKF93862.1 - 3.7e-73 246.4 24.7 3.7e-73 246.4 24.7 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKF93862.1 - 3.7e-25 87.4 1.6 2.7e-24 84.6 0.2 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KKF93862.1 - 7.4e-13 48.4 0.0 3.6e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKF93862.1 - 3.3e-12 47.2 0.2 1.2e-05 25.7 0.0 3.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KKF93862.1 - 1.1e-10 41.3 1.6 1.8e-10 40.7 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KKF93862.1 - 0.00041 20.2 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase_fungal PF17667.1 KKF93863.1 - 1.6e-74 251.1 0.2 2.4e-47 161.6 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase Homeodomain PF00046.29 KKF93864.1 - 1.6e-09 37.4 0.2 3.5e-09 36.4 0.2 1.6 1 0 0 1 1 1 1 Homeodomain Adaptin_binding PF10199.9 KKF93865.1 - 3.1e-11 43.9 1.5 7.5e-11 42.7 1.5 1.7 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 F-box PF00646.33 KKF93865.1 - 0.0046 16.8 0.1 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain ABC_tran PF00005.27 KKF93866.1 - 1.6e-53 180.9 0.0 1.4e-31 109.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKF93866.1 - 2.6e-52 178.2 26.0 3.1e-31 109.0 8.3 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KKF93866.1 - 8.2e-10 38.5 0.4 0.0031 17.0 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKF93866.1 - 6.6e-08 33.3 0.1 0.001 19.6 0.1 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KKF93866.1 - 8.9e-07 29.0 0.3 0.0069 16.5 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKF93866.1 - 9.4e-07 28.9 0.0 0.02 14.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KKF93866.1 - 7e-06 26.1 0.5 0.22 11.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKF93866.1 - 4.3e-05 23.2 0.3 0.23 11.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KKF93866.1 - 0.00046 20.6 0.0 0.69 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KKF93866.1 - 0.00054 19.7 0.0 0.26 11.0 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 KKF93866.1 - 0.00079 19.7 0.3 1.6 9.0 0.1 3.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KKF93866.1 - 0.0009 18.6 0.2 0.73 9.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin T2SSE PF00437.20 KKF93866.1 - 0.0034 16.5 0.0 0.38 9.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KKF93866.1 - 0.0037 16.9 0.0 0.52 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KKF93866.1 - 0.017 15.2 4.6 0.16 12.0 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA PF00004.29 KKF93866.1 - 0.024 15.0 0.1 19 5.7 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KKF93866.1 - 0.026 14.6 0.1 3 7.9 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 KKF93866.1 - 0.03 14.0 0.2 9.4 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKF93866.1 - 0.052 14.0 0.1 22 5.5 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.15 KKF93866.1 - 0.052 12.3 0.1 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF815 PF05673.13 KKF93866.1 - 0.058 12.5 0.2 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KKF93866.1 - 0.13 11.8 0.1 8.6 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 KKF93866.1 - 0.16 11.1 0.2 13 4.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 KKF93866.1 - 0.17 12.4 0.9 35 4.9 0.1 3.1 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KKF93866.1 - 0.17 11.2 0.1 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.6 KKF93866.1 - 0.36 10.5 2.4 2.4 7.8 0.0 2.7 3 0 0 3 3 2 0 AAA ATPase domain SecY PF00344.20 KKF93867.1 - 1.1e-69 235.0 9.6 1.5e-69 234.6 9.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KKF93867.1 - 3.3e-17 62.0 0.2 1e-16 60.5 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p IPPT PF01715.17 KKF93868.1 - 1e-57 195.6 0.2 1e-57 195.6 0.2 1.6 2 0 0 2 2 2 1 IPP transferase IPT PF01745.16 KKF93868.1 - 0.1 12.0 0.0 0.57 9.5 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase zf-met PF12874.7 KKF93868.1 - 0.2 12.1 0.4 0.42 11.1 0.4 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Aconitase PF00330.20 KKF93869.1 - 6.9e-112 374.8 2.3 6.6e-111 371.5 2.3 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKF93869.1 - 3.3e-27 95.4 0.0 6.6e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Fungal_trans PF04082.18 KKF93870.1 - 4.5e-18 65.2 0.0 7.2e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF93870.1 - 4.9e-09 36.2 9.6 8.6e-09 35.4 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KKF93871.1 - 2.6e-45 154.4 0.0 4.4e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF93871.1 - 7.9e-28 97.0 0.1 6.3e-27 94.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KKF93871.1 - 0.049 12.4 0.6 0.6 8.8 0.0 2.7 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 EB1 PF03271.17 KKF93872.1 - 1.7e-17 63.4 2.0 3.2e-17 62.5 2.0 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KKF93872.1 - 6e-07 29.6 1.7 1.4e-06 28.5 0.6 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain Suppressor_APC PF11414.8 KKF93872.1 - 0.038 14.1 1.2 0.11 12.5 1.2 1.7 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein CH_2 PF06294.11 KKF93872.1 - 0.097 12.8 0.1 0.2 11.8 0.1 1.6 1 1 0 1 1 1 0 CH-like domain in sperm protein T3SSipB PF16535.5 KKF93873.1 - 0.0029 18.1 0.8 0.0034 17.9 0.8 1.1 1 0 0 1 1 1 1 Type III cell invasion protein SipB Hormone_1 PF00103.20 KKF93873.1 - 0.0096 15.7 0.1 0.011 15.5 0.1 1.0 1 0 0 1 1 1 1 Somatotropin hormone family XhlA PF10779.9 KKF93873.1 - 0.012 15.8 0.9 0.024 14.8 0.9 1.5 1 0 0 1 1 1 0 Haemolysin XhlA KxDL PF10241.9 KKF93873.1 - 0.02 15.2 3.3 0.027 14.7 3.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein SNARE PF05739.19 KKF93873.1 - 0.025 14.6 0.4 0.025 14.6 0.4 2.0 2 0 0 2 2 2 0 SNARE domain DUF4559 PF15112.6 KKF93873.1 - 0.079 12.6 3.2 0.088 12.5 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Peptidase_S8 PF00082.22 KKF93878.1 - 0.005 16.1 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family BolA PF01722.18 KKF93879.1 - 2.9e-09 37.1 0.0 7.5e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein ACC_central PF08326.12 KKF93880.1 - 3.3e-265 881.9 0.0 4.2e-265 881.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KKF93880.1 - 1e-182 608.2 0.0 1.4e-182 607.8 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KKF93880.1 - 4.4e-52 176.6 0.0 8.2e-52 175.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KKF93880.1 - 1.3e-27 96.5 0.1 2.7e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KKF93880.1 - 3.2e-21 75.5 0.0 4e-19 68.7 0.0 3.4 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KKF93880.1 - 1e-17 63.7 0.1 2.2e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KKF93880.1 - 0.0021 17.6 0.0 0.0052 16.4 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KKF93880.1 - 0.003 17.6 0.0 0.0089 16.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain GxGYxYP_N PF16216.5 KKF93880.1 - 0.0053 17.0 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Beta_protein PF14350.6 KKF93880.1 - 0.11 11.8 0.0 0.29 10.5 0.0 1.7 1 0 0 1 1 1 0 Beta protein ATPgrasp_Ter PF15632.6 KKF93880.1 - 0.17 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon NUDE_C PF04880.13 KKF93881.1 - 4.1e-25 89.3 10.8 4.1e-25 89.3 10.8 2.3 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region PSII_Pbs27 PF13326.6 KKF93881.1 - 0.007 16.7 3.5 0.007 16.7 3.5 1.8 1 1 1 2 2 2 1 Photosystem II Pbs27 Filament PF00038.21 KKF93881.1 - 0.021 14.4 31.1 0.13 11.9 14.3 2.4 1 1 1 2 2 2 0 Intermediate filament protein WXG100 PF06013.12 KKF93881.1 - 0.23 11.7 7.3 27 5.1 0.1 3.7 3 1 0 3 3 3 0 Proteins of 100 residues with WXG ZapB PF06005.12 KKF93881.1 - 0.26 11.8 37.8 0.26 11.8 11.1 3.9 1 1 3 4 4 4 0 Cell division protein ZapB Fez1 PF06818.15 KKF93881.1 - 0.27 11.7 29.4 2 8.8 16.8 2.4 1 1 1 2 2 2 0 Fez1 Tropomyosin_1 PF12718.7 KKF93881.1 - 0.57 10.3 37.1 1.3 9.2 21.4 3.1 1 1 1 2 2 2 0 Tropomyosin like ADIP PF11559.8 KKF93881.1 - 0.92 9.6 29.1 3.3 7.8 11.0 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.9 KKF93881.1 - 1.1 8.0 20.8 0.1 11.4 13.6 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Chibby PF14645.6 KKF93881.1 - 1.3 9.5 13.9 4.1 7.8 3.4 2.3 1 1 1 2 2 2 0 Chibby family DUF836 PF05768.14 KKF93881.1 - 1.3 9.4 5.6 0.91 10.0 3.3 1.9 1 1 1 2 2 2 0 Glutaredoxin-like domain (DUF836) TSKS PF15358.6 KKF93881.1 - 2.4 6.4 15.5 0.69 8.2 12.8 1.4 1 1 0 1 1 1 0 Testis-specific serine kinase substrate CENP-F_leu_zip PF10473.9 KKF93881.1 - 3.1 7.8 35.2 1.1 9.3 12.3 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 KKF93881.1 - 5.6 7.4 25.2 0.51 10.7 4.6 3.8 1 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 KKF93881.1 - 7.2 6.7 37.4 5.7 7.0 8.0 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 KKF93881.1 - 7.6 4.3 21.3 0.83 7.5 15.8 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF745 PF05335.13 KKF93881.1 - 8.6 6.0 17.1 0.27 10.9 8.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Spc7 PF08317.11 KKF93881.1 - 9.8 4.9 30.2 24 3.7 30.0 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Zip PF02535.22 KKF93883.1 - 2e-26 93.0 10.6 2.4e-24 86.2 8.3 2.4 2 1 1 3 3 3 2 ZIP Zinc transporter Presenilin PF01080.17 KKF93884.1 - 1 8.0 6.0 1.2 7.8 6.0 1.2 1 0 0 1 1 1 0 Presenilin CRIM PF16978.5 KKF93886.1 - 4e-23 82.1 1.0 7.6e-23 81.2 0.0 2.0 1 1 1 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KKF93886.1 - 5.8e-07 29.8 0.2 1.1e-06 28.9 0.2 1.7 1 1 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KKF93886.1 - 0.00083 19.5 0.0 0.0025 18.0 0.0 1.8 2 0 0 2 2 2 1 TUG ubiquitin-like domain RBD PF02196.15 KKF93886.1 - 0.00094 19.2 0.1 0.0017 18.4 0.1 1.4 1 0 0 1 1 1 1 Raf-like Ras-binding domain FAM176 PF14851.6 KKF93886.1 - 1.8 8.2 6.4 0.15 11.7 1.6 1.7 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 KKF93886.1 - 6.4 7.2 10.8 2.2 8.7 6.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Translin PF01997.16 KKF93887.1 - 1.8e-43 148.9 0.0 2.2e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Translin family ERG4_ERG24 PF01222.17 KKF93888.1 - 4.3e-139 464.0 19.3 5e-139 463.8 19.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF2955 PF11168.8 KKF93888.1 - 2.8 7.8 9.9 0.57 10.0 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2955) ATP-synt_C PF00137.21 KKF93889.1 - 1.8e-34 117.8 33.8 1.5e-21 76.5 15.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L7Ae PF01248.26 KKF93890.1 - 1.2e-24 85.9 0.1 1.5e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KKF93890.1 - 9.9e-05 22.4 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KKF93890.1 - 0.00078 19.3 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain DUF4878 PF12870.7 KKF93890.1 - 0.08 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) hSac2 PF12456.8 KKF93891.1 - 6.6e-26 90.3 0.1 1.8e-17 63.1 0.0 2.3 1 1 1 2 2 2 2 Inositol phosphatase Syja_N PF02383.18 KKF93891.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 SacI homology domain Methyltransf_34 PF11312.8 KKF93892.1 - 4.1e-97 325.1 0.0 4.9e-97 324.9 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Transketolase_N PF00456.21 KKF93893.1 - 5e-157 522.1 0.0 6.3e-157 521.8 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KKF93893.1 - 1.8e-43 148.3 0.0 3.4e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KKF93893.1 - 4.5e-15 55.6 0.0 1.2e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KKF93893.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase N_BRCA1_IG PF16158.5 KKF93895.1 - 1.4e-16 61.1 0.0 6.5e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KKF93895.1 - 2.2e-09 37.0 23.5 0.00092 19.0 4.6 3.5 3 0 0 3 3 3 3 Zinc finger, ZZ type Aconitase PF00330.20 KKF93896.1 - 9.5e-144 479.8 0.0 1.4e-143 479.2 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) COPIIcoated_ERV PF07970.12 KKF93896.1 - 1.3e-37 129.8 0.1 2.3e-37 129.0 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Aconitase_C PF00694.19 KKF93896.1 - 8.7e-37 126.4 0.0 1.5e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain ERGIC_N PF13850.6 KKF93896.1 - 9.9e-22 77.1 0.0 1.8e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Actin PF00022.19 KKF93897.1 - 1.8e-126 422.1 0.0 8.8e-126 419.8 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKF93897.1 - 0.2 10.5 0.0 9.4 4.9 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein 2-oxoacid_dh PF00198.23 KKF93899.1 - 4.5e-78 261.9 0.1 7.8e-78 261.1 0.1 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KKF93899.1 - 6.5e-17 61.1 1.5 1.4e-16 60.1 1.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KKF93899.1 - 8.3e-06 25.5 1.1 0.0002 21.1 0.6 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 KKF93899.1 - 0.00012 22.7 0.8 0.0097 16.6 0.3 2.4 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.19 KKF93899.1 - 0.013 15.4 0.3 0.026 14.4 0.3 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 KKF93899.1 - 0.046 13.7 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 KKF93899.1 - 0.077 12.2 0.2 0.44 9.7 0.1 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Histone_H2A_C PF16211.5 KKF93900.1 - 3.6e-21 74.6 2.3 6.6e-21 73.7 2.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KKF93900.1 - 1.1e-16 61.4 0.0 1.5e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KKF93900.1 - 9.8e-06 25.8 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKF93901.1 - 1.7e-21 77.0 3.1 2.1e-21 76.7 3.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KKF93901.1 - 6e-05 23.2 0.8 0.0001 22.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KKF93901.1 - 0.00024 21.5 0.0 0.00042 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KKF93901.1 - 0.034 13.8 0.1 0.081 12.6 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain DnaJ PF00226.31 KKF93902.1 - 6e-26 90.4 1.0 6e-26 90.4 1.0 2.9 3 0 0 3 3 3 1 DnaJ domain zf-C2H2_jaz PF12171.8 KKF93902.1 - 3.1e-11 43.2 2.1 6.5e-11 42.2 2.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKF93902.1 - 1e-09 38.5 1.2 2.4e-09 37.3 1.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKF93902.1 - 3.4e-05 24.1 0.3 8.6e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KKF93902.1 - 0.0044 17.4 0.5 0.012 16.1 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF4136 PF13590.6 KKF93902.1 - 0.009 16.6 0.4 0.019 15.6 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4136) zf-C2H2_4 PF13894.6 KKF93902.1 - 0.022 15.6 0.2 0.076 13.9 0.2 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger ELF PF03317.13 KKF93902.1 - 0.075 13.0 0.1 12 5.9 0.1 2.7 2 0 0 2 2 2 0 ELF protein RPT PF13446.6 KKF93902.1 - 0.11 12.5 0.0 0.39 10.7 0.0 2.0 1 1 0 1 1 1 0 A repeated domain in UCH-protein zf-C2H2_6 PF13912.6 KKF93902.1 - 0.22 11.5 0.9 0.61 10.2 0.9 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4422 PF14393.6 KKF93902.1 - 1.5 8.6 4.3 7.7 6.3 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4422) Cys_Met_Meta_PP PF01053.20 KKF93903.1 - 1.3e-32 112.8 0.0 2.2e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pkinase_fungal PF17667.1 KKF93904.1 - 5.5e-49 167.0 0.3 7.1e-49 166.7 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase DEAD PF00270.29 KKF93905.1 - 2.8e-47 160.7 0.0 3.9e-46 157.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF93905.1 - 2.1e-29 102.1 0.1 3.5e-28 98.2 0.3 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PRAI PF00697.22 KKF93905.1 - 0.00045 20.0 0.1 0.00095 19.0 0.1 1.5 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase ResIII PF04851.15 KKF93905.1 - 0.0021 18.1 0.0 0.007 16.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 KKF93905.1 - 0.048 13.4 1.1 0.082 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) Mitoc_mL59 PF18126.1 KKF93906.1 - 6.3e-44 149.4 0.2 7.5e-44 149.2 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 14-3-3 PF00244.20 KKF93907.1 - 1.4e-106 355.0 2.1 1.7e-106 354.7 2.1 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 KKF93907.1 - 0.13 12.8 3.2 0.75 10.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat IATP PF04568.12 KKF93908.1 - 8.6e-27 93.4 0.2 9.3e-27 93.3 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DivIC PF04977.15 KKF93908.1 - 1.1 9.1 5.7 1.8 8.4 5.7 1.5 1 1 0 1 1 1 0 Septum formation initiator Nsp1_C PF05064.13 KKF93909.1 - 3.7e-40 136.4 1.1 3.7e-40 136.4 1.1 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KKF93909.1 - 1.2e-09 38.9 156.4 2.6e-05 25.0 26.5 6.5 1 1 5 6 6 6 3 Nucleoporin FG repeat region Laminin_II PF06009.12 KKF93909.1 - 0.014 15.4 4.6 1.9 8.5 0.5 2.3 2 0 0 2 2 2 0 Laminin Domain II ERM PF00769.19 KKF93909.1 - 0.1 12.4 4.7 0.15 11.8 4.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family RepB PF07506.11 KKF93909.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 RepB plasmid partitioning protein NPV_P10 PF05531.12 KKF93909.1 - 0.31 11.5 1.8 0.82 10.2 0.1 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.6 KKF93909.1 - 0.75 10.2 6.8 21 5.6 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 KKF93909.1 - 1.4 9.0 4.3 3.5 7.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KKF93909.1 - 4.7 7.0 6.0 3.5 7.4 1.7 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF724) V-SNARE PF05008.15 KKF93909.1 - 7.1 7.1 6.4 2.5 8.5 0.7 2.7 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF5102 PF17104.5 KKF93910.1 - 4.4e-99 332.2 0.5 4.4e-99 332.2 0.5 2.3 3 1 0 3 3 3 1 Domain of unknown function (DUF5102) eIF2_C PF09173.11 KKF93911.1 - 5.8e-34 116.2 0.5 1.4e-33 115.0 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KKF93911.1 - 1.8e-23 83.1 2.3 3.3e-22 79.0 2.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KKF93911.1 - 3.9e-10 40.0 0.2 8.1e-10 39.0 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKF93911.1 - 0.0036 17.4 0.0 0.0075 16.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KKF93911.1 - 0.0048 16.9 1.0 0.013 15.5 0.1 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 KKF93911.1 - 0.016 15.1 0.3 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase BRF1 PF07741.13 KKF93914.1 - 0.13 12.6 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain HrpF PF06266.12 KKF93914.1 - 0.43 10.9 4.8 22 5.4 1.8 2.9 2 1 1 3 3 3 0 HrpF protein DUF2179 PF10035.9 KKF93914.1 - 0.51 10.1 2.5 31 4.4 0.1 3.8 1 1 3 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2179) Cupredoxin_1 PF13473.6 KKF93917.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain Cu_bind_like PF02298.17 KKF93917.1 - 0.017 15.1 0.1 0.037 14.0 0.1 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain Cas_csx3 PF09620.10 KKF93917.1 - 0.025 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Tropomodulin PF03250.14 KKF93918.1 - 0.082 13.0 0.7 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Tropomodulin Inp1 PF12634.7 KKF93919.1 - 9.4e-42 142.3 0.0 2e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Cupin_2 PF07883.11 KKF93920.1 - 2e-08 33.8 0.0 3.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Aminotran_4 PF01063.19 KKF93921.1 - 1.3e-19 70.9 0.0 1.6e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV RSN1_7TM PF02714.15 KKF93922.1 - 6.6e-65 219.1 21.7 8.2e-65 218.8 21.7 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RseC_MucC PF04246.12 KKF93922.1 - 3.1 7.7 4.7 9.6 6.2 4.7 1.8 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC EF1_GNE PF00736.19 KKF93923.1 - 2.7e-31 107.6 1.0 4.4e-31 106.9 1.0 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KKF93923.1 - 1.1e-12 48.1 7.3 1.1e-12 48.1 7.3 2.8 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region Astro_capsid_p PF12226.8 KKF93923.1 - 0.14 11.2 4.5 0.2 10.8 4.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Proteasom_Rpn13 PF04683.13 KKF93924.1 - 2.8e-25 88.7 0.0 1.1e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 Proteasome complex subunit Rpn13 ubiquitin receptor RRM_1 PF00076.22 KKF93924.1 - 3.2e-12 46.1 0.1 0.00019 21.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPN13_C PF16550.5 KKF93924.1 - 5.8e-07 29.7 0.1 2.1e-06 27.9 0.1 1.9 1 1 0 1 1 1 1 UCH-binding domain GTP-bdg_M PF16360.5 KKF93924.1 - 0.13 12.9 0.5 0.37 11.4 0.5 1.8 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region RRM_7 PF16367.5 KKF93924.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif DNA_pol_phi PF04931.13 KKF93924.1 - 1.4 6.9 12.5 2.2 6.3 12.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi CPL PF08144.11 KKF93925.1 - 5.4e-32 111.1 0.0 9.7e-30 103.8 0.0 3.6 3 0 0 3 3 3 1 CPL (NUC119) domain CTI PF06934.11 KKF93925.1 - 0.055 12.0 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) PUF PF00806.19 KKF93925.1 - 0.17 11.7 0.0 0.54 10.1 0.0 1.9 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat RNA_pol_Rpb4 PF03874.16 KKF93926.1 - 2.2e-25 89.3 4.9 2.8e-25 89.0 4.9 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ada3 PF10198.9 KKF93926.1 - 0.0087 16.2 0.3 0.014 15.5 0.2 1.5 1 1 0 1 1 1 1 Histone acetyltransferases subunit 3 Spexin PF15171.6 KKF93926.1 - 0.065 13.4 0.5 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin AXIN1_TNKS_BD PF16646.5 KKF93926.1 - 0.073 14.0 0.0 0.14 13.1 0.0 1.5 1 0 0 1 1 1 0 Axin-1 tankyrase binding domain PaREP1 PF05942.11 KKF93926.1 - 0.076 13.0 0.4 0.099 12.6 0.4 1.2 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family VWA_2 PF13519.6 KKF93927.1 - 5.5e-24 84.9 0.1 2.1e-23 83.0 0.0 2.0 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KKF93927.1 - 2.2e-11 44.3 0.1 3.3e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KKF93927.1 - 5.6e-09 36.1 0.0 7.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KKF93927.1 - 0.01 15.7 3.7 0.021 14.7 1.1 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF1776 PF08643.10 KKF93927.1 - 0.037 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HisG_C PF08029.11 KKF93928.1 - 0.07 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 HisG, C-terminal domain SUI1 PF01253.22 KKF93929.1 - 1.1e-23 83.6 0.1 1.1e-23 83.6 0.1 1.8 2 0 0 2 2 2 1 Translation initiation factor SUI1 FAM150 PF15129.6 KKF93929.1 - 0.0069 16.5 0.1 0.01 16.0 0.1 1.3 1 0 0 1 1 1 1 FAM150 family MscS_TM PF12794.7 KKF93929.1 - 0.11 11.4 0.6 0.14 11.0 0.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF5611 PF18446.1 KKF93929.1 - 0.54 11.2 4.6 1.1 10.1 0.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5611) Peptidase_C15 PF01470.17 KKF93930.1 - 2.4e-11 44.2 0.0 1.2e-05 25.6 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase Oxidored_FMN PF00724.20 KKF93931.1 - 5.2e-65 219.9 0.0 9.3e-65 219.1 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Zip PF02535.22 KKF93933.1 - 0.002 17.4 11.8 0.002 17.4 11.8 2.1 2 0 0 2 2 2 1 ZIP Zinc transporter GREB1 PF15782.5 KKF93933.1 - 0.022 11.9 16.6 0.025 11.7 16.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4638 PF15472.6 KKF93933.1 - 0.6 9.8 9.5 0.78 9.4 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) Lin-8 PF03353.15 KKF93933.1 - 0.84 9.1 17.5 1.7 8.1 17.5 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ALMT PF11744.8 KKF93933.1 - 1.7 7.4 13.2 3.2 6.5 13.2 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter dsRBD2 PF17842.1 KKF93933.1 - 2.1 8.6 7.1 4.9 7.4 7.1 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 Endostatin PF06482.11 KKF93933.1 - 2.4 7.6 18.2 4.6 6.6 18.2 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Otopetrin PF03189.13 KKF93933.1 - 3.4 6.4 6.4 4.6 5.9 6.4 1.3 1 0 0 1 1 1 0 Otopetrin ORC2 PF04084.14 KKF93934.1 - 7.7e-98 327.5 0.0 9.4e-98 327.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 FANC_SAP PF18081.1 KKF93934.1 - 0.02 15.0 0.4 0.14 12.4 0.4 2.5 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain Cwf_Cwc_15 PF04889.12 KKF93934.1 - 0.087 12.5 6.4 0.14 11.9 6.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PGP_phosphatase PF09419.10 KKF93935.1 - 6.4e-62 208.1 0.0 1.1e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Abhydrolase_2 PF02230.16 KKF93935.1 - 7e-10 39.1 0.0 1.4e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_like PF13242.6 KKF93935.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like Abhydrolase_6 PF12697.7 KKF93935.1 - 0.12 12.9 5.4 0.17 12.4 4.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Alk_phosphatase PF00245.20 KKF93936.1 - 5.1e-66 223.3 0.1 4.8e-65 220.1 0.1 2.0 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 KKF93936.1 - 3e-08 33.7 0.0 4.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKF93936.1 - 3.9e-06 26.5 0.0 7.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KKF93936.1 - 0.0021 16.7 0.1 0.0034 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KKF93936.1 - 0.0028 17.1 0.1 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 Metalloenzyme superfamily PglZ PF08665.12 KKF93936.1 - 0.05 13.7 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 PglZ domain LCCL PF03815.19 KKF93937.1 - 4.5e-21 74.8 0.0 9.8e-21 73.7 0.1 1.5 2 0 0 2 2 2 1 LCCL domain TGT PF01702.18 KKF93938.1 - 8.5e-66 222.5 0.0 1.1e-65 222.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PE_PPE_C PF12484.8 KKF93938.1 - 3.8 8.5 6.4 2.9 8.9 0.1 2.8 3 0 0 3 3 3 0 Polymorphic PE/PPE proteins C terminal CENP-I PF07778.11 KKF93939.1 - 1.7e-37 129.4 0.0 1e-35 123.5 0.0 2.1 1 1 0 1 1 1 1 Mis6 Acetyltransf_7 PF13508.7 KKF93940.1 - 2.5e-06 27.8 0.0 6.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKF93940.1 - 2.6e-06 27.6 0.0 1.7e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKF93940.1 - 5.5e-06 26.3 0.0 1.4e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKF93940.1 - 0.013 15.6 0.0 0.71 9.9 0.1 2.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKF93940.1 - 0.028 14.4 0.0 0.14 12.2 0.0 2.2 1 1 0 1 1 1 0 FR47-like protein Pkinase PF00069.25 KKF93941.1 - 1.9e-70 237.3 0.0 2.4e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF93941.1 - 1.5e-32 112.9 0.0 2.1e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KKF93941.1 - 5.9e-12 46.1 5.0 5.9e-12 46.1 5.0 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KKF93941.1 - 7e-06 25.2 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 KKF93941.1 - 0.00025 21.3 0.0 0.00092 19.5 0.0 1.8 2 0 0 2 2 2 1 C2 domain Kinase-like PF14531.6 KKF93941.1 - 0.0046 16.3 0.0 0.011 15.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KKF93941.1 - 0.2 11.3 0.1 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3384 PF11864.8 KKF93942.1 - 1.1e-115 387.4 0.5 2.1e-115 386.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KKF93942.1 - 5e-52 176.2 0.0 8.8e-52 175.4 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KKF93942.1 - 5.3e-36 124.4 5.6 4.4e-32 111.6 0.3 3.6 4 0 0 4 4 4 3 Tuberin CAS_CSE1 PF03378.15 KKF93943.1 - 4e-162 539.7 0.1 8.7e-162 538.6 0.1 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KKF93943.1 - 3.9e-149 496.5 0.1 5.8e-149 495.9 0.1 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KKF93943.1 - 5.1e-14 51.9 0.2 3.3e-13 49.4 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Zwint PF15556.6 KKF93943.1 - 0.0081 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 ZW10 interactor V-ATPase_H_N PF03224.14 KKF93943.1 - 0.013 14.8 0.0 0.13 11.5 0.0 2.6 2 1 0 2 2 2 0 V-ATPase subunit H WD40 PF00400.32 KKF93944.1 - 1.5e-17 63.6 7.9 0.029 15.2 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF93944.1 - 1.9e-07 31.3 0.6 0.027 14.8 0.1 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKF93944.1 - 2.9e-05 24.0 0.1 1.1 9.2 0.1 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KKF93944.1 - 0.0011 17.6 0.0 0.58 8.6 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 KKF93944.1 - 0.0033 17.3 0.0 3.1 7.9 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat CLTH PF10607.9 KKF93944.1 - 0.0065 16.4 0.2 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40_3 PF15911.5 KKF93944.1 - 0.047 13.7 0.2 58 3.8 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Dynamin_M PF01031.20 KKF93945.1 - 4.6e-100 334.5 0.0 7e-100 333.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KKF93945.1 - 2.4e-56 190.4 0.0 4.2e-56 189.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KKF93945.1 - 1.3e-29 102.2 2.5 3.2e-29 100.9 2.5 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KKF93945.1 - 1.8e-05 24.8 0.3 0.0002 21.4 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KKF93945.1 - 0.19 11.4 1.3 8.7 5.9 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KKF93946.1 - 8.3e-16 58.7 0.0 4.5e-15 56.4 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKF93946.1 - 7.3e-10 39.1 2.2 0.00043 20.2 0.5 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKF93946.1 - 0.00016 21.2 0.0 0.094 12.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKF93946.1 - 0.001 18.8 0.1 0.0028 17.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 KKF93946.1 - 0.0015 16.2 0.2 0.0019 15.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_25 PF13481.6 KKF93946.1 - 0.0018 17.9 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KKF93946.1 - 0.0028 18.2 0.0 0.0043 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KKF93946.1 - 0.0093 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 KKF93946.1 - 0.0094 16.4 0.0 0.059 13.8 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KKF93946.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 KKF93946.1 - 0.026 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KKF93946.1 - 0.037 14.3 0.2 0.072 13.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KKF93946.1 - 0.039 13.7 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KKF93946.1 - 0.043 14.2 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KKF93946.1 - 0.053 13.6 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KKF93946.1 - 0.058 13.7 0.4 0.23 11.8 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 KKF93946.1 - 0.063 13.4 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KKF93946.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_14 PF13173.6 KKF93946.1 - 0.12 12.4 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KKF93946.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 KKF93946.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 KKF93946.1 - 0.14 10.7 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKF93946.1 - 0.15 12.0 0.6 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KKF93946.1 - 0.17 11.8 0.2 0.32 10.9 0.2 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 KKF93946.1 - 0.18 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 KKF93946.1 - 0.18 11.3 0.2 0.29 10.7 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DNA_pol_E_B PF04042.16 KKF93947.1 - 1.1e-46 158.9 0.0 1.4e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KKF93947.1 - 1.7e-39 134.9 0.0 2.6e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain PGA2 PF07543.12 KKF93948.1 - 1.5e-30 106.0 4.1 2.9e-30 105.0 4.1 1.4 1 1 0 1 1 1 1 Protein trafficking PGA2 PALP PF00291.25 KKF93949.1 - 9.9e-68 228.7 1.2 1.1e-67 228.5 1.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cellulase PF00150.18 KKF93950.1 - 8.3e-08 32.0 1.9 1.1e-07 31.6 0.0 2.2 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Radical_SAM PF04055.21 KKF93950.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily Glyco_hydro_17 PF00332.18 KKF93951.1 - 2.4e-08 33.9 0.3 6.6e-08 32.5 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Hamartin PF04388.12 KKF93952.1 - 6.1e-15 55.0 1.7 6.1e-15 55.0 1.7 4.4 3 1 0 3 3 3 2 Hamartin protein DUF5346 PF17281.2 KKF93953.1 - 0.046 13.8 0.2 0.2 11.7 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5346) ETF PF01012.21 KKF93954.1 - 2.2e-47 161.3 0.8 2.6e-47 161.0 0.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain CPSase_sm_chain PF00988.22 KKF93955.1 - 4.9e-47 158.9 0.0 7.8e-47 158.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KKF93955.1 - 5.4e-45 153.5 0.0 7.5e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKF93955.1 - 0.0001 22.1 0.2 0.017 14.9 0.1 2.5 1 1 0 2 2 2 2 Peptidase C26 ArfGap PF01412.18 KKF93956.1 - 3e-30 104.7 0.1 9.4e-30 103.1 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf RRM_1 PF00076.22 KKF93957.1 - 2.4e-33 113.8 1.1 1.5e-16 59.9 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKF93957.1 - 1.1e-05 25.5 0.0 0.038 14.1 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 KKF93957.1 - 0.0055 17.0 3.6 3.6 7.8 0.0 3.9 2 2 2 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 KKF93957.1 - 0.021 14.4 0.0 2.7 7.6 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4783 PF16022.5 KKF93957.1 - 0.064 13.4 0.1 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) RRM_Rrp7 PF17799.1 KKF93957.1 - 0.067 13.0 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DbpA PF03880.15 KKF93957.1 - 0.07 13.1 0.9 7.3 6.7 0.1 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain Limkain-b1 PF11608.8 KKF93957.1 - 0.18 11.9 0.8 3.5 7.8 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 MCM_bind PF09739.9 KKF93957.1 - 0.64 8.4 3.3 1 7.7 3.3 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor FAD_binding_1 PF00667.20 KKF93958.1 - 3.8e-27 95.3 0.0 6.6e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavoprotein PF02441.19 KKF93958.1 - 1.5e-14 54.0 0.0 2.8e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein DUF3097 PF11296.8 KKF93958.1 - 0.05 12.8 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) FlgN PF05130.12 KKF93959.1 - 0.0088 16.6 3.2 0.0088 16.6 3.2 2.3 2 0 0 2 2 2 1 FlgN protein G_path_suppress PF15991.5 KKF93959.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.7 3 0 0 3 3 3 0 G-protein pathway suppressor Fib_alpha PF08702.10 KKF93959.1 - 0.18 12.0 7.0 0.97 9.6 3.7 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3824 PF12868.7 KKF93959.1 - 0.65 10.7 4.4 0.19 12.4 1.0 1.8 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF4806 PF16064.5 KKF93959.1 - 0.89 9.9 2.5 11 6.4 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4806) CwsA PF10814.8 KKF93959.1 - 4.5 7.4 6.6 0.58 10.3 0.7 2.4 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA Mito_carr PF00153.27 KKF93960.1 - 1.7e-59 197.8 2.6 3e-21 75.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.13 KKF93961.1 - 2.9e-151 504.8 1.2 4.3e-146 487.7 0.3 2.5 1 1 1 2 2 2 2 RINT-1 / TIP-1 family DUF1542 PF07564.11 KKF93961.1 - 0.26 11.4 2.7 0.2 11.8 0.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) COG2 PF06148.11 KKF93961.1 - 0.5 10.5 6.6 1.3 9.2 3.0 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ATP-synt_C PF00137.21 KKF93962.1 - 6e-11 42.5 13.9 1e-10 41.8 13.9 1.4 1 0 0 1 1 1 1 ATP synthase subunit C Ribosomal_S25 PF03297.15 KKF93963.1 - 1.4e-35 121.6 4.9 1.5e-35 121.4 4.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Rrf2 PF02082.20 KKF93963.1 - 0.0041 17.4 0.1 0.0056 17.0 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator Fe_dep_repress PF01325.19 KKF93963.1 - 0.0062 16.7 0.1 0.029 14.6 0.0 2.0 1 1 1 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 KKF93963.1 - 0.0089 15.6 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KKF93963.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 MarR family RNA_pol_Rpc34 PF05158.12 KKF93963.1 - 0.015 14.7 0.4 0.032 13.6 0.1 1.4 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit HTH_27 PF13463.6 KKF93963.1 - 0.022 15.3 0.2 0.027 15.0 0.2 1.3 1 1 0 1 1 1 0 Winged helix DNA-binding domain EAP30 PF04157.16 KKF93963.1 - 0.055 12.7 0.1 0.064 12.5 0.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family MHC_I PF00129.18 KKF93963.1 - 0.095 12.3 0.2 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Ribosomal_S7 PF00177.21 KKF93964.1 - 9.7e-38 129.1 1.4 1.4e-37 128.6 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_5 PF13444.6 KKF93965.1 - 1.4e-05 25.7 0.0 0.081 13.6 0.0 2.5 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKF93965.1 - 3.9e-05 23.6 0.0 0.0068 16.3 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKF93965.1 - 4.8e-05 23.6 0.0 0.00013 22.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KKF93965.1 - 0.00014 21.9 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 KKF93965.1 - 0.00045 20.6 0.0 0.00088 19.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKF93965.1 - 0.02 15.0 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKF93965.1 - 0.025 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ald_Xan_dh_C2 PF02738.18 KKF93966.1 - 2.2e-209 696.5 2.4 2.2e-209 696.5 2.4 1.7 2 0 0 2 2 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase SPO22 PF08631.10 KKF93966.1 - 2.5e-50 171.5 6.3 7.2e-48 163.5 0.8 3.4 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like FAD_binding_5 PF00941.21 KKF93966.1 - 9.1e-46 155.7 0.0 2.4e-45 154.3 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KKF93966.1 - 1.1e-30 105.8 0.1 4.4e-30 103.9 0.1 2.2 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 KKF93966.1 - 1e-29 103.1 0.0 1e-29 103.1 0.0 2.4 2 0 0 2 2 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain PAS PF00989.25 KKF93966.1 - 0.0051 16.8 0.1 0.023 14.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold TPR_12 PF13424.6 KKF93966.1 - 0.011 16.1 0.0 4.4 7.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF218 PF02698.17 KKF93966.1 - 0.022 14.8 0.0 0.068 13.2 0.0 1.8 1 0 0 1 1 1 0 DUF218 domain Sel1 PF08238.12 KKF93966.1 - 0.037 14.7 0.5 8.6 7.2 0.1 3.0 2 0 0 2 2 2 0 Sel1 repeat Gly_acyl_tr_C PF08444.10 KKF93966.1 - 0.087 13.1 0.0 3.8 7.8 0.0 2.9 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region TPR_8 PF13181.6 KKF93966.1 - 0.2 11.9 0.6 5.1 7.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.18 KKF93966.1 - 0.57 10.3 2.4 1.2 9.4 2.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 KKF93966.1 - 9.6 5.7 15.0 18 4.8 15.0 1.3 1 0 0 1 1 1 0 Spt20 family BTB_2 PF02214.22 KKF93967.1 - 3.5e-08 33.7 0.0 0.00024 21.4 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Mito_carr PF00153.27 KKF93968.1 - 3.3e-42 142.3 8.7 7.4e-16 57.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RVT_1 PF00078.27 KKF93969.1 - 2.6e-58 197.2 0.0 3.3e-30 105.3 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) SopE_GEF PF07487.13 KKF93969.1 - 0.0063 16.6 0.0 6.9 6.8 0.0 2.7 2 0 0 2 2 2 2 SopE GEF domain SpoIIE PF07228.12 KKF93969.1 - 0.035 14.0 0.2 1.6 8.6 0.3 2.3 1 1 1 2 2 2 0 Stage II sporulation protein E (SpoIIE) PH_TFIIH PF08567.11 KKF93969.1 - 0.12 12.7 0.0 28 5.1 0.0 2.5 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain POTRA_1 PF08478.10 KKF93969.1 - 0.17 12.2 0.2 38 4.7 0.0 2.7 3 0 0 3 3 3 0 POTRA domain, FtsQ-type Ribosomal_L12 PF00542.19 KKF93969.1 - 0.2 12.1 5.3 7.9 6.9 0.4 2.6 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Pkinase PF00069.25 KKF93970.1 - 1.3e-52 178.8 0.0 8.6e-30 104.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF93970.1 - 5e-37 127.6 0.0 2.8e-18 66.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Thioredoxin_7 PF13899.6 KKF93971.1 - 8.6e-17 61.1 0.1 1.9e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KKF93971.1 - 4.4e-10 39.2 0.0 8.6e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KKF93971.1 - 3.1e-07 30.5 0.0 7.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 KKF93971.1 - 0.047 13.6 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Inhibitor_I53 PF11714.8 KKF93971.1 - 0.081 13.1 0.6 7.7 6.8 0.2 2.8 2 1 0 2 2 2 0 Thrombin inhibitor Madanin RRM_1 PF00076.22 KKF93972.1 - 1.9e-42 142.9 0.0 1.3e-16 60.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKF93972.1 - 6e-06 26.2 0.2 0.0022 18.0 0.1 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KKF93972.1 - 0.00012 22.1 0.0 0.0017 18.4 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KKF93972.1 - 0.00018 21.5 0.1 0.051 13.7 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 KKF93972.1 - 0.00062 19.6 0.0 0.049 13.5 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KKF93972.1 - 0.058 13.0 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_11 PF08241.12 KKF93973.1 - 2.5e-11 44.1 0.0 4.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.8 KKF93973.1 - 6.5e-11 42.8 2.2 1.1e-10 42.1 2.2 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 KKF93973.1 - 9e-11 42.3 0.0 2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF93973.1 - 0.00023 21.9 0.0 0.0011 19.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KKF93973.1 - 0.00079 19.2 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KKF93973.1 - 0.00093 19.1 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF93973.1 - 0.0016 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKF93973.1 - 0.0045 16.3 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KKF93973.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KKF93973.1 - 0.075 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain MutS_V PF00488.21 KKF93975.1 - 3.1e-73 245.8 0.8 5.3e-73 245.1 0.8 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKF93975.1 - 8.9e-34 117.4 1.6 2.6e-33 115.9 1.6 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KKF93975.1 - 3.1e-27 95.0 0.1 3.2e-12 46.7 0.0 2.8 3 0 0 3 3 3 2 MutS domain I MutS_II PF05188.17 KKF93975.1 - 1.1e-07 32.2 0.0 2.9e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KKF93975.1 - 0.00065 20.0 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Med28 PF11594.8 KKF93975.1 - 0.088 12.9 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Mediator complex subunit 28 AAA_29 PF13555.6 KKF93975.1 - 0.18 11.6 0.1 0.44 10.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-met PF12874.7 KKF93976.1 - 0.00013 22.2 0.3 0.00033 21.0 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKF93976.1 - 0.0067 16.7 0.4 0.013 15.8 0.4 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF2614 PF11023.8 KKF93976.1 - 0.05 13.7 0.1 0.093 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-C2H2_jaz PF12171.8 KKF93976.1 - 0.1 13.0 0.2 0.22 11.9 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Prenyltrans PF00432.21 KKF93977.1 - 1.5e-60 200.6 8.1 2.5e-13 49.5 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KKF93977.1 - 3.3e-06 26.4 0.2 0.0097 15.0 0.0 3.0 1 1 2 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KKF93977.1 - 6.8e-06 25.4 0.0 0.18 10.9 0.0 4.2 1 1 4 5 5 5 4 Squalene-hopene cyclase N-terminal domain RhoGAP PF00620.27 KKF93979.1 - 1.1e-27 96.8 0.0 1.8e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain SARS_X4 PF08779.10 KKF93979.1 - 0.09 13.0 0.4 0.21 11.8 0.1 1.7 2 0 0 2 2 2 0 SARS coronavirus X4 like EIIA-man PF03610.16 KKF93979.1 - 0.21 11.8 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 PTS system fructose IIA component RRS1 PF04939.12 KKF93980.1 - 6.1e-56 188.8 2.3 7e-56 188.6 2.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) U1snRNP70_N PF12220.8 KKF93980.1 - 0.2 12.3 0.1 0.2 12.3 0.1 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DAP3 PF10236.9 KKF93981.1 - 4.5e-85 285.6 0.0 5.4e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 KKF93981.1 - 0.097 12.4 0.6 1.8 8.4 0.2 2.6 2 1 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.23 KKF93982.1 - 1.3e-102 341.7 0.0 2.1e-102 341.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKF93982.1 - 6.6e-29 100.3 0.2 1.3e-28 99.4 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKF93982.1 - 4.2e-22 78.4 1.4 1.2e-21 76.9 1.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKF93982.1 - 4.1e-18 65.9 0.8 1.8e-17 63.8 0.3 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKF93982.1 - 2.4e-07 30.3 0.0 1.8e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKF93982.1 - 6.1e-07 29.5 0.0 2.4e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KKF93982.1 - 0.00079 19.2 0.2 0.0023 17.8 0.2 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KKF93982.1 - 0.024 14.5 0.0 0.072 13.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKF93982.1 - 0.13 12.0 0.0 0.86 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 KKF93982.1 - 0.14 12.8 3.8 0.2 12.3 0.5 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal SurA_N_3 PF13624.6 KKF93982.1 - 0.23 11.2 1.0 1.3 8.7 0.3 2.4 2 0 0 2 2 2 0 SurA N-terminal domain AAA PF00004.29 KKF93983.1 - 1.2e-49 168.1 0.0 4.5e-43 146.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKF93983.1 - 2.2e-15 56.2 0.4 2.7e-09 36.7 0.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KKF93983.1 - 2.9e-06 27.8 3.2 0.11 12.9 0.2 4.3 2 2 2 4 4 4 1 AAA ATPase domain NACHT PF05729.12 KKF93983.1 - 3.3e-06 27.1 0.8 0.064 13.2 0.0 3.6 3 1 0 3 3 3 2 NACHT domain AAA_2 PF07724.14 KKF93983.1 - 0.00012 22.2 0.0 0.058 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KKF93983.1 - 0.00045 20.2 0.1 0.35 10.8 0.1 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKF93983.1 - 0.00075 19.7 0.0 0.16 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKF93983.1 - 0.0021 18.6 0.0 1.2 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KKF93983.1 - 0.0021 17.8 0.0 0.0083 15.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KKF93983.1 - 0.0074 16.3 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKF93983.1 - 0.015 15.5 3.0 3.8 7.8 0.3 4.2 3 2 1 4 4 3 0 AAA domain RNA_helicase PF00910.22 KKF93983.1 - 0.019 15.3 0.0 3.9 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 KKF93983.1 - 0.021 14.8 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KKF93983.1 - 0.022 14.3 0.1 1.2 8.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KKF93983.1 - 0.023 15.1 0.2 2.3 8.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain SKI PF01202.22 KKF93983.1 - 0.03 14.4 0.2 6.1 6.9 0.1 2.5 2 0 0 2 2 2 0 Shikimate kinase Viral_helicase1 PF01443.18 KKF93983.1 - 0.086 12.6 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Vps4_C PF09336.10 KKF93983.1 - 0.098 12.7 0.0 3 7.9 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Zeta_toxin PF06414.12 KKF93983.1 - 0.1 11.9 0.1 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 KKF93983.1 - 0.12 11.8 1.0 0.24 10.8 0.2 2.0 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.6 KKF93983.1 - 0.15 12.2 0.1 6.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family IstB_IS21 PF01695.17 KKF93983.1 - 0.16 11.7 0.1 3.9 7.2 0.1 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein XPA_C PF05181.12 KKF93984.1 - 3.4e-25 87.7 2.8 7e-25 86.7 2.8 1.6 1 0 0 1 1 1 1 XPA protein C-terminus SR-25 PF10500.9 KKF93984.1 - 0.61 9.7 12.4 0.061 12.9 1.2 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Endonuc_Holl PF10107.9 KKF93984.1 - 2.9 7.7 8.2 0.073 12.9 1.2 1.8 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Pkinase PF00069.25 KKF93985.1 - 3.3e-66 223.4 0.0 4.3e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF93985.1 - 2.3e-31 109.0 0.0 3.2e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKF93985.1 - 4.7e-06 25.8 0.1 7.2e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KKF93985.1 - 0.00036 19.9 0.0 0.0053 16.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KKF93985.1 - 0.00045 20.2 0.0 0.0012 18.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKF93985.1 - 0.0075 15.6 0.2 0.046 13.1 0.2 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KKF93985.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KKF93985.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Synaptobrevin PF00957.21 KKF93986.1 - 9e-14 51.0 0.2 1.6e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KKF93986.1 - 2e-12 47.0 0.0 4.3e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 Regulated-SNARE-like domain Sec63 PF02889.16 KKF93987.1 - 1.8e-132 440.3 0.0 7.9e-74 248.1 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KKF93987.1 - 4.8e-42 143.7 0.0 1.2e-20 74.0 0.0 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KKF93987.1 - 6e-18 65.4 0.0 5e-11 42.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKF93987.1 - 4.7e-16 59.1 0.4 3.8e-06 27.2 0.0 4.7 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KKF93987.1 - 3.9e-05 23.9 0.0 0.078 13.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KKF93987.1 - 0.00014 21.6 0.1 0.32 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 KKF93987.1 - 0.00016 21.8 0.0 0.00065 19.9 0.0 2.1 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA PF00004.29 KKF93987.1 - 0.0069 16.8 0.0 1.7 9.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF505 PF04458.12 KKF93987.1 - 0.11 10.9 0.0 0.18 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) PTS_IIB PF02302.17 KKF93987.1 - 0.15 12.8 0.0 8.4 7.2 0.0 2.9 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit AAA_19 PF13245.6 KKF93987.1 - 0.67 10.3 4.1 5.6 7.3 0.1 3.1 4 0 0 4 4 3 0 AAA domain FMN_dh PF01070.18 KKF93988.1 - 3.5e-103 345.3 0.2 8.6e-80 268.4 0.1 2.2 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Ras PF00071.22 KKF93988.1 - 2e-33 115.3 0.0 3.3e-31 108.1 0.0 2.3 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KKF93988.1 - 1.8e-25 89.5 0.0 3.4e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Cyt-b5 PF00173.28 KKF93988.1 - 4.5e-21 74.8 0.0 4.5e-21 74.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Arf PF00025.21 KKF93988.1 - 7.7e-07 28.7 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Glu_synthase PF01645.17 KKF93988.1 - 0.00069 18.9 0.1 0.0011 18.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KKF93988.1 - 0.0068 15.4 0.5 0.019 13.9 0.3 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KKF93988.1 - 0.047 13.1 0.1 0.082 12.3 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase MMR_HSR1 PF01926.23 KKF93988.1 - 0.13 12.4 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RTP1_C2 PF10304.9 KKF93988.1 - 0.21 11.3 0.5 0.45 10.3 0.5 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 DLIC PF05783.11 KKF93988.1 - 0.24 10.2 0.0 0.39 9.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) BRO1 PF03097.18 KKF93989.1 - 3.9e-132 440.7 1.5 3.9e-132 440.7 1.5 2.4 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KKF93989.1 - 2.1e-76 257.1 18.2 2.1e-76 257.1 18.2 2.4 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Spt20 PF12090.8 KKF93989.1 - 1.4 8.5 20.3 4.9 6.7 20.3 1.9 1 0 0 1 1 1 0 Spt20 family DnaJ_C PF01556.18 KKF93990.1 - 3.8e-39 134.1 0.0 5.1e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKF93990.1 - 2.4e-24 85.2 1.0 4.1e-24 84.5 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKF93990.1 - 1.6e-10 41.2 16.5 3.6e-10 40.1 16.5 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KKF93990.1 - 5.1e-05 23.2 10.8 0.0037 17.2 0.7 2.8 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_C7 PF14522.6 KKF93990.1 - 0.25 11.4 5.0 0.36 10.9 0.8 2.5 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 KKF93990.1 - 9.2 6.3 7.9 3.4 7.7 0.6 2.2 1 1 2 3 3 3 0 zinc-ribbons DUF3496 PF12001.8 KKF93993.1 - 0.066 13.6 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) Peptidase_C12 PF01088.21 KKF93995.1 - 0.035 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 MazE_antitoxin PF04014.18 KKF93997.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin Ala_racemase_C PF00842.21 KKF93997.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain Fig1 PF12351.8 KKF93999.1 - 7.3e-06 26.0 8.6 3.2e-05 24.0 0.1 3.0 1 1 1 3 3 3 2 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KKF93999.1 - 0.042 13.5 2.4 0.066 12.8 0.2 1.8 1 1 0 2 2 2 0 SUR7/PalI family Ost4 PF10215.9 KKF93999.1 - 7.3 6.5 10.9 8 6.4 3.4 2.7 2 0 0 2 2 2 0 Oligosaccaryltransferase PTPA PF03095.15 KKF94000.1 - 2.3e-97 326.1 0.0 3.8e-97 325.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Hexokinase_2 PF03727.16 KKF94002.1 - 4.2e-52 176.9 0.0 7.1e-52 176.2 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KKF94002.1 - 1.3e-34 119.9 0.0 1.8e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PRIMA1 PF16101.5 KKF94003.1 - 0.68 10.0 0.0 0.68 10.0 0.0 3.4 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 CoA_transf_3 PF02515.17 KKF94004.1 - 2.1e-126 422.0 0.0 2.3e-126 421.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Peptidase_M22 PF00814.25 KKF94005.1 - 1.1e-44 153.1 0.1 2.1e-20 73.6 0.0 3.9 1 1 1 2 2 2 2 Glycoprotease family C2 PF00168.30 KKF94006.1 - 9.7e-76 250.7 0.0 3.3e-17 62.7 0.0 5.5 5 0 0 5 5 5 5 C2 domain Proteasome PF00227.26 KKF94006.1 - 6.2e-45 153.0 0.2 9.7e-45 152.4 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit SMP_LBD PF17047.5 KKF94006.1 - 5.3e-05 22.8 0.0 9.6e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 KKF94006.1 - 0.051 13.3 0.1 8.6 6.1 0.0 3.9 4 0 0 4 4 4 0 N-terminal C2 in EEIG1 and EHBP1 proteins DUF720 PF05302.11 KKF94006.1 - 1.8 8.4 4.4 3.7 7.4 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Pkinase PF00069.25 KKF94007.1 - 8.9e-61 205.5 1.0 2e-60 204.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF94007.1 - 2.1e-36 125.6 1.3 2.6e-36 125.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.22 KKF94007.1 - 2.6e-19 68.8 29.9 7.2e-11 41.8 10.3 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 KKF94007.1 - 2.8e-19 69.0 16.5 2.7e-11 43.4 6.4 3.6 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 KKF94007.1 - 2.7e-14 53.6 1.0 1.2e-13 51.6 1.0 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 KKF94007.1 - 4.2e-05 23.8 0.3 0.00012 22.4 0.1 1.8 2 0 0 2 2 2 1 C2 domain DUF5599 PF18141.1 KKF94007.1 - 0.052 13.8 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5599) Haspin_kinase PF12330.8 KKF94007.1 - 0.094 11.6 0.1 0.094 11.6 0.1 1.9 2 0 0 2 2 2 0 Haspin like kinase domain She9_MDM33 PF05546.11 KKF94008.1 - 7.7e-80 267.4 6.2 1.1e-79 266.9 6.2 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family OEP PF02321.18 KKF94008.1 - 0.0085 15.9 3.7 0.016 15.0 3.7 1.4 1 0 0 1 1 1 1 Outer membrane efflux protein ZapB PF06005.12 KKF94008.1 - 0.058 13.8 0.4 0.058 13.8 0.4 3.2 3 0 0 3 3 3 0 Cell division protein ZapB DUF1319 PF07028.11 KKF94008.1 - 0.11 12.7 0.4 2.3 8.5 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) PAS_9 PF13426.7 KKF94008.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 PAS domain CDPS PF16715.5 KKF94008.1 - 0.21 11.2 3.2 0.44 10.2 3.2 1.5 1 0 0 1 1 1 0 Cyclodipeptide synthase BCAS2 PF05700.11 KKF94008.1 - 0.4 10.3 11.7 0.21 11.3 2.0 2.6 2 1 1 3 3 3 0 Breast carcinoma amplified sequence 2 (BCAS2) PspA_IM30 PF04012.12 KKF94008.1 - 0.95 9.0 13.1 0.32 10.5 3.2 2.7 1 1 1 2 2 2 0 PspA/IM30 family DUF4407 PF14362.6 KKF94008.1 - 1.8 7.8 7.8 3.9 6.8 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YscO PF07321.12 KKF94008.1 - 2.2 8.2 15.6 0.019 14.9 4.3 2.5 2 1 1 3 3 3 0 Type III secretion protein YscO OmpH PF03938.14 KKF94008.1 - 3.8 7.8 7.2 6.2 7.2 6.6 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIVA PF05103.13 KKF94008.1 - 5.3 7.1 11.0 6.6 6.8 1.4 3.1 3 0 0 3 3 3 0 DivIVA protein DUF1180 PF06679.12 KKF94008.1 - 7.5 6.9 15.0 0.95 9.9 8.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) HAD PF12710.7 KKF94009.1 - 7.7e-16 59.0 0.0 9.4e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KKF94009.1 - 0.0018 17.9 0.0 0.01 15.3 0.0 1.9 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KKF94009.1 - 0.0034 17.7 0.7 0.089 13.1 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase PHAT PF09246.10 KKF94009.1 - 0.017 15.0 0.0 0.043 13.7 0.0 1.6 2 0 0 2 2 2 0 PHAT Glyco_hydro_16 PF00722.21 KKF94010.1 - 4.5e-45 153.3 3.5 4.5e-45 153.3 3.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 KKF94010.1 - 0.011 16.2 7.0 0.024 15.1 7.0 1.6 1 0 0 1 1 1 0 Chitin recognition protein BLOC1S3 PF15753.5 KKF94010.1 - 1.3 9.1 7.1 2.1 8.5 7.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 SR-25 PF10500.9 KKF94010.1 - 9.9 5.7 11.6 16 5.0 11.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Utp8 PF10395.9 KKF94012.1 - 0.0031 16.1 0.0 0.0046 15.5 0.0 1.1 1 0 0 1 1 1 1 Utp8 family AAA PF00004.29 KKF94013.1 - 2.6e-06 27.9 2.1 7.9e-06 26.3 2.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKF94013.1 - 0.0023 18.2 3.1 0.0058 16.9 0.7 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKF94013.1 - 0.0027 18.1 2.5 0.0028 18.0 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain TsaE PF02367.17 KKF94013.1 - 0.067 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KKF94013.1 - 0.16 12.5 0.0 0.41 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Chs7 PF12271.8 KKF94014.1 - 4.3e-120 400.4 17.2 4.9e-120 400.2 17.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Cyclin PF08613.11 KKF94015.1 - 2.4e-12 47.5 1.5 2.4e-12 47.5 1.5 3.8 3 2 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 KKF94015.1 - 0.00038 20.2 0.1 0.00038 20.2 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF2681 PF10883.8 KKF94015.1 - 0.017 15.5 5.5 0.017 15.5 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) RLL PF10036.9 KKF94015.1 - 0.079 12.8 3.1 0.19 11.6 3.1 1.5 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Peptidase_M14 PF00246.24 KKF94016.1 - 5.9e-24 85.4 1.3 9.4e-23 81.4 1.9 1.9 1 1 1 2 2 2 1 Zinc carboxypeptidase RNA_pol_Rpc34 PF05158.12 KKF94017.1 - 6.2e-97 325.0 0.0 8.3e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 KKF94017.1 - 0.0014 19.2 0.0 0.066 13.9 0.0 2.9 3 0 0 3 3 3 1 Replication protein A C terminal B-block_TFIIIC PF04182.12 KKF94017.1 - 0.027 14.6 0.3 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Mnd1 PF03962.15 KKF94017.1 - 0.039 14.3 1.7 0.45 10.8 0.1 2.9 3 0 0 3 3 3 0 Mnd1 HTH domain Ribosomal_L14 PF00238.19 KKF94018.1 - 2.3e-33 114.9 0.0 2.7e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e EB1 PF03271.17 KKF94019.1 - 0.1 12.9 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 EB1-like C-terminal motif DUF5427 PF10310.9 KKF94020.1 - 1.2e-156 522.4 0.2 1.4e-156 522.1 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) GATase PF00117.28 KKF94021.1 - 1.2e-36 126.2 0.0 2.5e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KKF94021.1 - 2.5e-36 123.6 0.2 5.1e-36 122.6 0.2 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KKF94021.1 - 4.1e-11 42.5 0.2 6.4e-06 25.5 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KKF94021.1 - 6.8e-09 35.8 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 KKF94021.1 - 0.0017 17.9 0.0 0.066 12.7 0.0 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 KKF94021.1 - 0.006 15.9 0.0 0.015 14.6 0.1 1.7 2 0 0 2 2 2 1 Arginosuccinate synthase tRNA_Me_trans PF03054.16 KKF94021.1 - 0.0085 14.9 0.1 0.024 13.4 0.1 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 KKF94021.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 KKF94021.1 - 0.05 13.4 0.1 0.1 12.3 0.1 1.7 1 1 0 1 1 1 0 PP-loop family PAPS_reduct PF01507.19 KKF94021.1 - 0.12 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family WD40 PF00400.32 KKF94022.1 - 1.1e-92 301.4 71.4 1.1e-11 45.1 0.5 16.1 15 2 0 15 15 14 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94022.1 - 8.6e-51 170.2 18.6 8.9e-05 22.7 0.1 12.4 2 1 10 13 13 13 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF94022.1 - 1.1e-19 70.6 28.5 0.0008 18.5 0.3 8.4 2 2 3 7 7 7 7 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KKF94022.1 - 2.3e-18 66.7 0.0 4.7e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 KKF94022.1 - 4.8e-17 62.6 0.3 8.4e-17 61.8 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase PD40 PF07676.12 KKF94022.1 - 2.7e-12 46.3 0.0 22 5.2 0.0 10.6 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KKF94022.1 - 2.1e-08 33.3 21.0 0.0062 15.2 0.1 7.7 3 3 5 8 8 8 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KKF94022.1 - 8.8e-08 31.1 4.7 0.1 11.1 0.1 5.0 3 1 2 5 5 5 2 Cytochrome D1 heme domain Robl_LC7 PF03259.17 KKF94022.1 - 4.6e-06 26.3 2.5 5.8 6.8 0.0 7.2 7 1 1 9 9 9 2 Roadblock/LC7 domain Fibrinogen_aC PF12160.8 KKF94022.1 - 5.9e-05 22.8 7.0 4 7.4 0.0 7.6 8 0 0 8 8 8 1 Fibrinogen alpha C domain CDtoxinA PF03498.14 KKF94022.1 - 0.00013 21.5 1.6 4.1 7.0 0.0 5.9 5 2 1 6 6 6 1 Cytolethal distending toxin A/C domain AAA_16 PF13191.6 KKF94022.1 - 0.004 17.6 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Nucleoporin_N PF08801.11 KKF94022.1 - 0.004 16.0 1.4 0.032 13.0 0.1 2.9 2 1 1 3 3 3 1 Nup133 N terminal like DUF5046 PF16465.5 KKF94022.1 - 0.007 15.9 0.1 5.5 6.3 0.0 4.5 3 3 2 5 5 5 1 Domain of unknown function (DUF5046) WD40_like PF17005.5 KKF94022.1 - 0.021 14.1 0.1 3.5 6.9 0.0 3.6 3 1 2 5 5 5 0 WD40-like domain AAA_19 PF13245.6 KKF94022.1 - 0.024 15.0 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PIN_8 PF18476.1 KKF94022.1 - 0.052 13.4 3.1 0.085 12.7 1.2 2.0 2 0 0 2 2 2 0 PIN like domain FLgD_tudor PF13861.6 KKF94022.1 - 0.15 12.3 2.0 1.2 9.4 0.0 3.6 4 1 0 4 4 3 0 FlgD Tudor-like domain Proteasome_A_N PF10584.9 KKF94022.1 - 2.5 7.9 6.5 39 4.0 0.1 5.3 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature Tubulin PF00091.25 KKF94023.1 - 7e-69 232.0 0.0 2.6e-68 230.1 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKF94023.1 - 8.5e-43 145.5 0.1 1.4e-42 144.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KKF94023.1 - 2.2e-05 24.8 0.0 5.5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KKF94023.1 - 0.0019 17.5 0.0 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KKF94023.1 - 0.0021 17.8 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain ABC_tran PF00005.27 KKF94024.1 - 3.9e-37 127.8 1.0 2.9e-22 79.6 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KKF94024.1 - 3.6e-19 68.6 8.9 3.6e-19 68.6 8.9 2.8 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 KKF94024.1 - 1.5e-10 41.4 4.5 0.0041 17.0 0.0 3.8 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKF94024.1 - 6e-07 30.2 15.9 0.021 15.3 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 KKF94024.1 - 1.2e-06 29.0 0.2 0.041 14.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KKF94024.1 - 3e-06 27.3 1.2 0.02 15.0 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKF94024.1 - 4e-06 26.9 2.8 0.045 13.7 0.1 3.9 2 1 1 4 4 4 2 RsgA GTPase AAA_29 PF13555.6 KKF94024.1 - 4.7e-06 26.3 0.3 0.063 13.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KKF94024.1 - 1.1e-05 25.8 2.1 0.094 13.1 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 KKF94024.1 - 2.2e-05 24.8 1.0 0.044 14.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 KKF94024.1 - 3.2e-05 23.5 4.4 1.3 8.4 0.0 3.9 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KKF94024.1 - 3.7e-05 23.9 0.0 0.23 11.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KKF94024.1 - 6.7e-05 22.8 7.3 0.27 10.9 0.0 4.0 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KKF94024.1 - 9.6e-05 22.7 0.0 0.58 10.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 KKF94024.1 - 0.00042 20.1 1.5 0.93 9.2 0.2 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KKF94024.1 - 0.00067 20.1 0.0 1.4 9.3 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKF94024.1 - 0.0016 18.4 0.0 3.4 7.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KKF94024.1 - 0.0024 18.2 0.0 2.6 8.5 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_30 PF13604.6 KKF94024.1 - 0.003 17.3 0.1 1 9.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 KKF94024.1 - 0.0035 17.3 0.2 2.1 8.2 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain MeaB PF03308.16 KKF94024.1 - 0.0041 16.1 3.2 1.1 8.1 0.0 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KKF94024.1 - 0.0066 16.7 0.2 1.6 8.9 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KKF94024.1 - 0.0077 15.8 1.2 1.7 8.2 0.7 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KKF94024.1 - 0.0093 15.9 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 KKF94024.1 - 0.01 15.8 0.9 3.6 7.5 0.0 2.8 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 KKF94024.1 - 0.01 15.9 5.8 5.4 7.0 0.0 4.2 4 1 0 4 4 4 0 Dynamin family ATP-synt_ab PF00006.25 KKF94024.1 - 0.011 15.4 0.0 0.29 10.8 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KKF94024.1 - 0.012 15.1 0.0 7 6.1 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 KKF94024.1 - 0.019 14.8 0.0 0.53 10.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KKF94024.1 - 0.022 14.8 0.3 3 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 KKF94024.1 - 0.053 13.1 6.2 5.4 6.5 0.0 4.1 4 1 1 5 5 5 0 AAA domain Zeta_toxin PF06414.12 KKF94024.1 - 0.059 12.6 2.1 3.1 7.0 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin TsaE PF02367.17 KKF94024.1 - 0.076 13.0 0.0 9.8 6.2 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KKF94024.1 - 0.076 12.2 0.1 10 5.2 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 KKF94024.1 - 0.62 10.5 7.7 21 5.5 0.5 3.9 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 KKF94024.1 - 3.1 7.8 9.7 2.2 8.3 0.0 3.7 4 0 0 4 4 4 0 Helicase HerA, central domain CHS5_N PF16892.5 KKF94025.1 - 0.059 13.3 0.1 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Chitin biosynthesis protein CHS5 N-terminus SOG2 PF10428.9 KKF94025.1 - 1.7 7.8 8.9 2 7.5 8.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NUDE_C PF04880.13 KKF94025.1 - 6.9 7.1 8.2 0.41 11.1 0.1 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region COX7a PF02238.15 KKF94026.1 - 0.12 12.8 0.1 0.31 11.5 0.1 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII Spermine_synth PF01564.17 KKF94027.1 - 1.4e-06 27.9 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 KKF94027.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Inositol_P PF00459.25 KKF94028.1 - 3.1e-53 181.0 1.5 1.2e-52 179.1 1.5 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.25 KKF94029.1 - 9.8e-18 64.5 0.0 2.6e-17 63.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF94029.1 - 6.3e-11 42.0 0.0 9e-10 38.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 KKF94029.1 - 0.01 15.5 0.8 0.024 14.3 0.3 1.9 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Phasin_2 PF09361.10 KKF94029.1 - 0.22 11.8 1.6 22 5.4 0.0 3.2 3 0 0 3 3 3 0 Phasin protein zf-primase PF09329.11 KKF94030.1 - 6.6e-19 67.5 1.0 1.2e-18 66.6 1.0 1.4 1 0 0 1 1 1 1 Primase zinc finger PBD PF00786.28 KKF94030.1 - 0.17 12.3 0.4 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 P21-Rho-binding domain YL1 PF05764.13 KKF94030.1 - 6.6 6.8 17.9 0.22 11.6 1.1 3.3 3 0 0 3 3 3 0 YL1 nuclear protein RNase_H2-Ydr279 PF09468.10 KKF94031.1 - 3.8e-34 118.2 0.0 1.7e-33 116.1 0.0 2.0 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KKF94031.1 - 1.9e-21 76.1 0.0 4.4e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain DASH_Duo1 PF08651.10 KKF94032.1 - 2.7e-06 27.0 1.9 9.8e-06 25.3 1.9 1.8 1 1 0 1 1 1 1 DASH complex subunit Duo1 SSFA2_C PF14723.6 KKF94032.1 - 0.0015 18.4 0.8 0.0021 18.0 0.8 1.3 1 0 0 1 1 1 1 Sperm-specific antigen 2 C-terminus Gag_spuma PF03276.14 KKF94032.1 - 0.1 11.0 1.2 0.11 10.9 0.4 1.5 1 1 1 2 2 2 0 Spumavirus gag protein MIF4G_like_2 PF09090.11 KKF94032.1 - 0.24 10.8 2.0 0.28 10.6 2.0 1.1 1 0 0 1 1 1 0 MIF4G like Casc1_N PF15927.5 KKF94032.1 - 6 6.5 14.4 7 6.3 13.3 1.6 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus ROKNT PF08067.11 KKF94033.1 - 0.15 12.4 0.5 0.15 12.4 0.5 2.3 2 0 0 2 2 2 0 ROKNT (NUC014) domain SurE PF01975.17 KKF94034.1 - 1.9e-54 184.4 0.0 2.8e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE TTL PF03133.15 KKF94034.1 - 5.6e-48 163.6 0.0 9.4e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Glyco_transf_4 PF13439.6 KKF94034.1 - 0.056 13.4 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ATPgrasp_YheCD PF14398.6 KKF94034.1 - 0.084 12.1 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KKF94034.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Cation_ATPase_C PF00689.21 KKF94035.1 - 4.4e-42 143.9 2.4 4.4e-42 143.9 2.4 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KKF94035.1 - 3.1e-33 114.8 0.3 3.1e-33 114.8 0.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKF94035.1 - 6.6e-23 82.1 0.1 1.8e-22 80.7 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKF94035.1 - 6.2e-20 71.1 0.0 1.3e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KKF94035.1 - 7e-10 38.5 0.1 2.3e-07 30.4 0.0 3.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKF94035.1 - 6e-05 22.9 0.3 0.00012 21.9 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKF94035.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SIR2 PF02146.17 KKF94036.1 - 1.6e-56 191.0 0.0 2.4e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KKF94036.1 - 0.00014 21.6 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KKF94036.1 - 0.0068 16.2 0.2 0.36 10.6 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Pox_Ag35 PF03286.14 KKF94036.1 - 0.083 12.7 0.1 0.083 12.7 0.1 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CutC PF03932.14 KKF94036.1 - 0.1 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 CutC family BUD22 PF09073.10 KKF94036.1 - 4.7 6.4 13.3 14 4.9 9.8 2.1 2 0 0 2 2 2 0 BUD22 DHDPS PF00701.22 KKF94037.1 - 2e-38 131.8 0.0 7.2e-30 103.7 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family Peptidase_M24 PF00557.24 KKF94038.1 - 4e-42 144.3 0.1 6.3e-42 143.6 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AhpC-TSA_2 PF13911.6 KKF94038.1 - 7.8e-11 42.1 0.0 1.3e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KKF94038.1 - 1.9e-07 31.1 0.0 4.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKF94038.1 - 0.0014 18.3 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Redoxin CCDC106 PF15794.5 KKF94038.1 - 0.23 11.1 1.8 0.42 10.3 1.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 FrhB_FdhB_N PF04422.13 KKF94039.1 - 0.094 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term PRKG1_interact PF15898.5 KKF94039.1 - 0.32 11.9 5.0 1 10.3 5.0 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain SPACA9 PF15120.6 KKF94039.1 - 0.34 10.7 6.9 0.87 9.4 1.5 2.3 1 1 1 2 2 2 0 Sperm acrosome-associated protein 9 Aminotran_4 PF01063.19 KKF94040.1 - 2.8e-20 73.1 0.0 3.3e-12 46.7 0.0 2.2 1 1 1 2 2 2 2 Amino-transferase class IV F_bP_aldolase PF01116.20 KKF94041.1 - 1.6e-92 310.0 0.1 1.8e-92 309.8 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CTP_transf_like PF01467.26 KKF94042.1 - 1.3e-16 61.1 2.7 5.5e-14 52.6 0.1 3.3 3 2 0 3 3 3 2 Cytidylyltransferase-like LTXXQ PF07813.12 KKF94042.1 - 0.034 14.9 1.7 0.064 14.0 1.7 1.3 1 0 0 1 1 1 0 LTXXQ motif family protein FAD_syn PF06574.12 KKF94042.1 - 0.21 11.4 0.5 23 4.8 0.3 3.0 3 0 0 3 3 3 0 FAD synthetase CAC1F_C PF16885.5 KKF94043.1 - 0.14 11.8 14.6 0.28 10.8 14.6 1.5 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Presenilin PF01080.17 KKF94043.1 - 0.48 9.1 10.2 0.73 8.5 10.2 1.3 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 KKF94044.1 - 3.4e-15 56.2 7.8 0.0081 17.0 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94044.1 - 0.00013 22.2 0.0 0.24 11.7 0.0 4.3 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 KKF94044.1 - 0.00087 19.0 0.0 0.037 13.6 0.0 2.1 1 1 0 1 1 1 1 CNH domain WD40_like PF17005.5 KKF94044.1 - 0.0016 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 KKF94044.1 - 0.005 15.8 0.1 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NUP214 PF16755.5 KKF94044.1 - 0.02 14.2 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 PDZ_1 PF12812.7 KKF94046.1 - 1.6e-46 156.2 0.0 1.4e-28 98.7 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KKF94046.1 - 1.6e-22 81.0 2.0 2.2e-20 74.1 0.0 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KKF94046.1 - 4.8e-11 42.3 0.2 0.002 17.9 0.1 4.2 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KKF94046.1 - 2.4e-09 37.4 0.8 0.0011 19.2 0.0 3.9 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 KKF94046.1 - 1.4e-05 25.4 0.0 0.027 14.8 0.0 3.4 3 0 0 3 3 3 2 PDZ domain Peptidase_S46 PF10459.9 KKF94046.1 - 0.0033 16.1 0.0 0.0058 15.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S46 Trypsin PF00089.26 KKF94046.1 - 0.0097 15.7 0.0 0.026 14.3 0.0 1.6 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.21 KKF94046.1 - 0.22 11.4 0.2 0.48 10.2 0.2 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DnaJ PF00226.31 KKF94047.1 - 2e-23 82.3 0.2 4.8e-23 81.1 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain CUE PF02845.16 KKF94048.1 - 2.9e-08 33.3 0.0 4.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 KKF94048.1 - 0.15 12.1 3.2 0.32 11.0 3.2 1.6 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 G2BR PF18442.1 KKF94048.1 - 0.4 10.4 10.2 0.95 9.2 10.2 1.6 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) COPI_assoc PF08507.10 KKF94049.1 - 1.3e-26 93.2 7.8 1.5e-26 93.0 7.8 1.0 1 0 0 1 1 1 1 COPI associated protein ATP1G1_PLM_MAT8 PF02038.16 KKF94049.1 - 0.19 11.2 1.5 0.62 9.5 1.5 1.9 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Apocytochr_F_C PF01333.19 KKF94050.1 - 0.22 11.5 7.8 72 3.5 0.0 4.7 2 1 1 5 5 5 0 Apocytochrome F, C-terminal FAD_binding_8 PF08022.12 KKF94051.1 - 5.3e-22 78.0 0.0 9.6e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KKF94051.1 - 4.7e-10 39.7 4.0 9.1e-10 38.7 4.0 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KKF94051.1 - 2.3e-05 24.6 0.0 3.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain LrgA PF03788.14 KKF94051.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 LrgA family DUF1640 PF07798.11 KKF94052.1 - 2.4e-43 148.2 6.2 2.6e-43 148.1 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 KKF94052.1 - 0.0032 16.9 0.2 0.0048 16.3 0.2 1.4 1 1 0 1 1 1 1 GNAT acetyltransferase 2 XhlA PF10779.9 KKF94052.1 - 0.021 15.1 2.2 0.25 11.6 0.2 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Peptidase_S46 PF10459.9 KKF94052.1 - 0.054 12.2 1.1 0.06 12.0 1.1 1.0 1 0 0 1 1 1 0 Peptidase S46 Spore_GerAC PF05504.11 KKF94052.1 - 0.061 13.6 1.0 0.075 13.2 1.0 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Avl9 PF09794.9 KKF94053.1 - 9e-118 393.3 0.0 1.5e-63 214.8 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.10 KKF94053.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Roughex PF06020.11 KKF94053.1 - 0.0061 15.7 0.3 0.013 14.7 0.3 1.5 1 0 0 1 1 1 1 Drosophila roughex protein DUF3482 PF11981.8 KKF94053.1 - 0.093 12.1 2.3 0.15 11.4 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Pho88 PF10032.9 KKF94054.1 - 8.6e-73 243.5 0.1 9.6e-73 243.3 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4512 PF14975.6 KKF94054.1 - 0.13 13.1 0.0 0.33 11.7 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) Uroplakin_II PF07353.12 KKF94056.1 - 0.049 13.1 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Uroplakin II Chorismate_synt PF01264.21 KKF94057.1 - 1.3e-135 451.3 0.0 1.5e-135 451.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF1992 PF09350.10 KKF94059.1 - 0.055 13.6 0.1 14 5.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) DUF3905 PF13045.6 KKF94063.1 - 0.089 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) RVT_2 PF07727.14 KKF94064.1 - 1.4e-43 149.3 0.0 3.3e-43 148.1 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KKF94065.1 - 0.00019 21.4 4.2 0.00028 20.8 4.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KKF94065.1 - 0.0011 18.8 2.1 0.0031 17.3 2.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KKF94065.1 - 0.089 12.5 1.1 0.15 11.8 1.1 1.3 1 0 0 1 1 1 0 Zinc knuckle HscB_4_cys PF18256.1 KKF94065.1 - 0.19 11.6 4.4 0.35 10.7 4.4 1.4 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Pil1 PF13805.6 KKF94067.1 - 7.8e-96 320.6 5.3 1.6e-95 319.6 5.3 1.5 1 0 0 1 1 1 1 Eisosome component PIL1 TMEM252 PF15664.5 KKF94067.1 - 0.02 14.6 0.2 0.036 13.8 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family PcfK PF14058.6 KKF94067.1 - 5.5 7.3 9.0 0.17 12.2 2.3 1.9 2 1 0 2 2 2 0 PcfK-like protein DUF2345 PF10106.9 KKF94068.1 - 2.3e-06 27.5 5.2 2.6e-06 27.4 5.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) DUF3540 PF12059.8 KKF94068.1 - 0.00064 19.6 3.4 0.0009 19.1 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3540) Epiglycanin_TR PF05647.11 KKF94068.1 - 0.031 14.2 9.4 0.046 13.6 8.6 1.7 1 1 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like Sarcoglycan_1 PF04790.13 KKF94068.1 - 0.039 13.3 0.5 0.045 13.1 0.5 1.1 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein GARS_A PF01071.19 KKF94068.1 - 0.13 12.1 5.0 1.8 8.3 5.1 2.0 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ribophorin_I PF04597.14 KKF94069.1 - 1.1e-143 479.6 2.4 1.3e-143 479.4 2.4 1.0 1 0 0 1 1 1 1 Ribophorin I Hexokinase_2 PF03727.16 KKF94070.1 - 1.9e-84 282.9 0.0 2.8e-84 282.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KKF94070.1 - 8.7e-72 241.2 0.0 1.8e-71 240.2 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Ank_2 PF12796.7 KKF94071.1 - 0.044 14.4 0.1 0.76 10.4 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) VTC PF09359.10 KKF94072.1 - 2.1e-96 322.6 0.4 1.1e-95 320.2 0.0 1.9 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 KKF94072.1 - 2.8e-09 37.4 8.6 0.0055 16.7 0.3 3.6 3 1 1 4 4 4 3 SPX domain DUF2805 PF10985.8 KKF94072.1 - 0.089 13.2 0.4 0.22 11.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) DUF202 PF02656.15 KKF94072.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) MARVEL PF01284.23 KKF94073.1 - 0.0031 17.6 10.9 0.0031 17.6 10.9 1.9 1 1 1 2 2 2 1 Membrane-associating domain Ninjurin PF04923.12 KKF94073.1 - 0.05 13.5 0.1 0.05 13.5 0.1 2.0 2 1 0 2 2 2 0 Ninjurin Peptidase_M56 PF05569.11 KKF94073.1 - 0.095 11.9 2.0 0.18 11.0 2.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 COX4 PF02936.14 KKF94073.1 - 0.35 10.9 3.3 7.5 6.6 0.0 3.3 3 1 0 3 3 3 0 Cytochrome c oxidase subunit IV GpcrRhopsn4 PF10192.9 KKF94073.1 - 0.79 9.1 11.0 3.6 6.9 0.4 2.3 2 1 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain Pox_EPC_I2-L1 PF12575.8 KKF94073.1 - 1.1 9.5 3.5 9.1 6.6 0.5 3.2 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 Chordopox_A13L PF05961.11 KKF94073.1 - 1.2 9.4 6.6 0.13 12.5 0.6 2.4 2 1 1 3 3 3 0 Chordopoxvirus A13L protein DUF1772 PF08592.11 KKF94073.1 - 1.3 9.3 4.9 8.4 6.7 4.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Vpu PF00558.19 KKF94073.1 - 1.4 8.8 5.3 2.4 8.0 0.8 2.3 2 0 0 2 2 2 0 Vpu protein MpPF26 PF07666.11 KKF94073.1 - 1.5 8.9 7.8 0.18 11.9 1.1 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF2721 PF11026.8 KKF94073.1 - 8.8 6.2 9.1 4.1 7.3 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) GTP_EFTU PF00009.27 KKF94074.1 - 1.4e-17 63.9 0.0 3.2e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KKF94074.1 - 5.7e-06 26.6 0.2 2.2e-05 24.7 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKF94074.1 - 0.12 12.5 0.0 0.33 11.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KKF94074.1 - 0.17 11.6 0.2 3.3 7.5 0.0 2.9 3 1 1 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Ran_BP1 PF00638.18 KKF94076.1 - 6.2e-52 175.0 0.9 1.3e-51 174.0 0.9 1.5 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KKF94076.1 - 0.00015 21.7 0.3 0.0011 18.9 0.3 2.0 1 1 0 1 1 1 1 WH1 domain PS-DH PF14765.6 KKF94076.1 - 0.012 14.9 0.2 0.024 13.9 0.2 1.4 1 0 0 1 1 1 0 Polyketide synthase dehydratase VID27_PH PF17747.1 KKF94076.1 - 0.077 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 VID27 PH-like domain CDC27 PF09507.10 KKF94076.1 - 0.18 11.2 16.6 0.24 10.8 16.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PHD20L1_u1 PF16660.5 KKF94076.1 - 0.4 11.5 3.2 0.72 10.6 3.2 1.4 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 YEATS PF03366.16 KKF94077.1 - 4.8e-21 74.5 0.2 1.4e-20 73.0 0.2 1.9 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KKF94077.1 - 0.00014 22.0 0.4 0.00032 20.8 0.4 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Aminotran_1_2 PF00155.21 KKF94079.1 - 1.4e-60 205.4 0.0 1.8e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKF94079.1 - 0.067 12.1 0.0 0.17 10.8 0.0 1.6 1 1 1 2 2 2 0 Aminotransferase class-V SAM_2 PF07647.17 KKF94080.1 - 1e-15 57.5 0.0 1.9e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KKF94080.1 - 8.3e-14 51.8 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KKF94080.1 - 1.9e-11 44.4 0.0 3.5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KKF94080.1 - 0.0013 18.6 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Rootletin PF15035.6 KKF94080.1 - 0.023 14.7 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Abhydrolase_3 PF07859.13 KKF94081.1 - 2.4e-43 148.5 0.0 3.1e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KKF94081.1 - 0.00072 18.3 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KKF94081.1 - 0.0025 17.3 0.0 0.0078 15.7 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 KKF94081.1 - 0.0097 14.8 0.8 0.025 13.5 0.1 1.9 2 1 1 3 3 3 1 Carboxylesterase family His_Phos_2 PF00328.22 KKF94082.1 - 3.7e-27 95.7 0.0 5e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Tho2 PF11262.8 KKF94083.1 - 0.54 9.4 8.5 0.95 8.6 8.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4746 PF15928.5 KKF94083.1 - 0.94 8.8 8.3 1.4 8.3 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) OmpH PF03938.14 KKF94083.1 - 2.7 8.3 12.2 5.3 7.4 12.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KKF94083.1 - 5 6.4 5.3 7.8 5.8 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2370 PF10176.9 KKF94084.1 - 0.095 12.3 0.3 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) PAP2_3 PF14378.6 KKF94084.1 - 0.18 11.5 1.5 0.68 9.6 1.5 2.1 1 1 0 1 1 1 0 PAP2 superfamily Pribosyltran PF00156.27 KKF94085.1 - 3.3e-05 23.5 0.0 5.6e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pex24p PF06398.11 KKF94086.1 - 7.5e-69 232.5 0.9 9.9e-69 232.1 0.9 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF5320 PF17253.2 KKF94086.1 - 0.056 14.5 1.4 0.5 11.5 0.3 3.0 3 1 0 3 3 3 0 Family of unknown function (DUF5320) Ribosomal_L50 PF10501.9 KKF94087.1 - 2.1e-19 69.7 0.0 4.7e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S Pep_deformylase PF01327.21 KKF94087.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase DUF5353 PF17304.2 KKF94088.1 - 0.03 14.1 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5353) CYYR1 PF10873.8 KKF94088.1 - 0.055 13.9 1.0 0.064 13.7 0.4 1.4 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 TPR_21 PF09976.9 KKF94088.1 - 0.086 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DAHP_synth_1 PF00793.20 KKF94089.1 - 3.3e-104 347.6 0.1 4.1e-104 347.3 0.1 1.1 1 0 0 1 1 1 1 DAHP synthetase I family AbiEi_1 PF09407.10 KKF94089.1 - 0.0074 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 AbiEi antitoxin C-terminal domain YIEGIA PF14045.6 KKF94089.1 - 0.14 11.0 0.1 0.26 10.1 0.1 1.3 1 0 0 1 1 1 0 YIEGIA protein ELO PF01151.18 KKF94091.1 - 4.7e-61 206.5 20.9 5.7e-61 206.2 20.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.16 KKF94092.1 - 9.5e-41 138.0 0.9 1.3e-40 137.5 0.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF4424 PF14415.6 KKF94092.1 - 0.033 13.4 0.1 0.033 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) DUF488 PF04343.13 KKF94092.1 - 0.11 13.1 0.3 0.58 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF488 Fungal_TACC PF12709.7 KKF94093.1 - 0.019 15.4 6.3 0.019 15.4 6.3 3.0 3 1 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins HALZ PF02183.18 KKF94093.1 - 0.041 14.1 12.6 0.043 14.0 0.8 3.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper YabA PF06156.13 KKF94093.1 - 0.063 13.9 23.8 1.5 9.5 0.7 4.0 2 2 1 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 KKF94093.1 - 0.077 13.4 35.3 0.3 11.5 22.1 2.2 1 1 1 2 2 2 0 Fez1 AAA_13 PF13166.6 KKF94093.1 - 0.35 9.5 26.6 0.46 9.1 26.6 1.1 1 0 0 1 1 1 0 AAA domain BST2 PF16716.5 KKF94093.1 - 0.71 10.5 25.8 0.67 10.6 4.6 3.1 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 NYD-SP28_assoc PF14775.6 KKF94093.1 - 0.78 9.9 6.5 8.3 6.6 2.5 3.0 2 1 0 2 2 2 0 Sperm tail C-terminal domain CEP63 PF17045.5 KKF94093.1 - 1.7 8.5 32.5 0.12 12.3 13.5 2.2 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa KASH_CCD PF14662.6 KKF94093.1 - 3.8 7.3 32.4 3.8 7.3 20.8 3.5 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KKF94093.1 - 4.1 7.4 32.5 0.82 9.7 3.4 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 KKF94093.1 - 5.7 7.1 22.2 0.67 10.1 10.1 3.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 KKF94093.1 - 6.8 7.2 14.4 2.8 8.4 2.1 4.3 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Retrotrans_gag PF03732.17 KKF94093.1 - 8.5 6.7 9.9 0.69 10.2 1.8 2.9 1 1 2 3 3 3 0 Retrotransposon gag protein Pet127 PF08634.10 KKF94094.1 - 6.7e-111 370.1 1.5 1.3e-110 369.1 1.5 1.5 1 0 0 1 1 1 1 Mitochondrial protein Pet127 SAM_decarbox PF01536.16 KKF94095.1 - 1.9e-134 448.2 0.0 2.3e-134 447.9 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Ribosomal_L4 PF00573.22 KKF94096.1 - 2.1e-36 125.4 0.4 2.9e-36 125.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KKF94096.1 - 3.3e-26 91.1 1.0 7.2e-26 90.1 1.0 1.6 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Aminotran_1_2 PF00155.21 KKF94097.1 - 3.4e-11 42.9 0.0 4.5e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Tannase PF07519.11 KKF94097.1 - 0.064 12.1 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase AMP-binding PF00501.28 KKF94098.1 - 2.2e-62 211.0 0.0 3.3e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 KKF94098.1 - 2.8e-12 45.8 5.8 0.0023 17.6 0.1 6.6 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 KKF94098.1 - 4.3e-12 46.2 0.0 8.7e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.6 KKF94098.1 - 0.23 11.3 16.3 1.4 8.7 0.6 5.8 6 1 0 6 6 6 0 Hexapeptide repeat of succinyl-transferase NOB1_Zn_bind PF08772.11 KKF94099.1 - 4.1e-31 106.9 2.0 6.7e-31 106.3 2.0 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KKF94099.1 - 6.9e-29 100.2 0.1 2.1e-28 98.7 0.0 1.9 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 KKF94099.1 - 0.0057 16.3 0.6 0.0057 16.3 0.6 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Rhodanese_C PF12368.8 KKF94099.1 - 0.05 14.0 0.5 0.096 13.1 0.5 1.3 1 0 0 1 1 1 0 Rhodanase C-terminal WRNPLPNID PF15017.6 KKF94099.1 - 3.2 8.7 19.0 1.3e+02 3.5 19.1 2.9 1 1 0 1 1 1 0 Putative WW-binding domain and destruction box CENP-N PF05238.13 KKF94099.1 - 4 6.6 7.0 6.8 5.9 0.0 2.1 2 0 0 2 2 2 0 Kinetochore protein CHL4 like Nop10p PF04135.12 KKF94100.1 - 1.1e-19 70.2 0.1 1.4e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Formyl_trans_N PF00551.19 KKF94101.1 - 1e-37 129.6 0.6 1.4e-37 129.2 0.6 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KKF94101.1 - 5.4e-09 35.7 0.0 1.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KKF94101.1 - 0.032 14.2 0.0 0.22 11.5 0.0 2.4 2 1 1 3 3 3 0 ACT domain DUF148 PF02520.17 KKF94101.1 - 0.056 13.5 1.3 4.5 7.4 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 RabGAP-TBC PF00566.18 KKF94102.1 - 1.3e-41 142.7 5.4 4.4e-41 140.9 5.4 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KKF94102.1 - 6.1e-08 32.3 0.0 3.7e-05 23.3 0.0 2.7 2 1 0 2 2 2 1 Rab-binding domain (RBD) Mso1_Sec1_bdg PF14475.6 KKF94103.1 - 4.1e-17 61.5 0.0 8.6e-17 60.5 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 SUIM_assoc PF16619.5 KKF94103.1 - 0.17 11.9 11.8 61 3.8 0.0 3.3 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L28e PF01778.17 KKF94104.1 - 5.7e-36 123.8 1.7 5.7e-36 123.8 1.7 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KKF94104.1 - 4.1e-25 88.3 20.1 4.1e-25 88.3 20.1 2.8 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KKF94104.1 - 4.2e-06 26.4 25.4 5.8e-06 25.9 25.4 1.1 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.13 KKF94104.1 - 0.0072 16.4 17.3 0.011 15.8 17.3 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FCH PF00611.23 KKF94104.1 - 0.033 14.5 1.6 0.033 14.5 1.6 2.0 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain PYC_OADA PF02436.18 KKF94104.1 - 0.074 12.8 0.9 0.14 11.9 0.9 1.6 1 0 0 1 1 1 0 Conserved carboxylase domain Nop14 PF04147.12 KKF94104.1 - 2.9 6.0 41.2 4.2 5.5 41.2 1.1 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_63 PF03200.16 KKF94105.1 - 1.9e-167 558.0 0.1 1.9e-167 558.0 0.1 3.5 3 1 0 3 3 3 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KKF94105.1 - 2.8e-70 237.0 0.2 1.9e-69 234.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Taxilin PF09728.9 KKF94105.1 - 3e-46 158.0 39.6 6.4e-31 107.7 10.8 2.6 2 1 1 3 3 3 2 Myosin-like coiled-coil protein PXB PF12828.7 KKF94105.1 - 6.6e-12 45.5 0.1 1.5e-09 38.0 0.1 2.7 1 1 0 1 1 1 1 PX-associated DUF3818 PF12825.7 KKF94105.1 - 3e-10 39.6 0.0 3e-10 39.6 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function in PX-proteins (DUF3818) TMF_TATA_bd PF12325.8 KKF94105.1 - 0.0012 19.1 30.7 0.012 15.9 4.1 3.7 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding DUF3573 PF12097.8 KKF94105.1 - 0.0042 16.0 1.0 0.0084 15.0 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) Trehalase PF01204.18 KKF94105.1 - 0.011 14.6 0.2 0.011 14.6 0.2 2.3 2 1 0 2 2 2 0 Trehalase TSC22 PF01166.18 KKF94105.1 - 0.087 13.2 0.3 0.087 13.2 0.3 4.2 5 0 0 5 5 5 0 TSC-22/dip/bun family APC_N_CC PF16689.5 KKF94105.1 - 2.6 8.2 8.6 0.69 10.0 1.0 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain M16C_assoc PF08367.11 KKF94106.1 - 8e-75 251.2 0.0 1.4e-74 250.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KKF94106.1 - 3.9e-32 111.7 0.0 1.9e-23 83.5 0.0 3.5 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKF94106.1 - 3.5e-10 40.0 0.0 7.9e-08 32.4 0.0 3.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) DUF2312 PF10073.9 KKF94106.1 - 0.071 12.8 0.5 0.19 11.4 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Orn_Arg_deC_N PF02784.16 KKF94107.1 - 2.4e-84 282.6 0.0 3.3e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KKF94107.1 - 2.3e-19 69.5 0.0 5.2e-19 68.3 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Peptidase_M16_C PF05193.21 KKF94108.1 - 6.9e-23 81.6 0.0 2.5e-17 63.5 0.0 3.5 3 2 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKF94108.1 - 4.3e-07 30.0 0.1 3.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KKF94108.1 - 0.0029 16.8 2.3 0.73 8.9 1.0 2.4 2 0 0 2 2 2 2 Peptidase M16C associated FAM212 PF15342.6 KKF94108.1 - 1 9.2 3.4 21 5.0 0.0 2.7 2 0 0 2 2 2 0 FAM212 family Astro_capsid_p PF12226.8 KKF94108.1 - 1.7 7.7 6.7 2.5 7.2 6.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNA_pol_3_Rpc31 PF11705.8 KKF94108.1 - 5.7 7.1 17.4 1.1 9.5 9.1 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DHHC PF01529.20 KKF94109.1 - 0.14 12.2 0.1 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Chs7 PF12271.8 KKF94110.1 - 3e-86 289.3 14.5 1.9e-80 270.3 11.3 2.0 1 1 1 2 2 2 2 Chitin synthase export chaperone MpPF26 PF07666.11 KKF94110.1 - 0.048 13.8 0.1 0.048 13.8 0.1 2.4 3 0 0 3 3 3 0 M penetrans paralogue family 26 Ssl1 PF04056.14 KKF94111.1 - 1.2e-51 175.3 0.0 1.1e-33 116.7 0.0 2.2 1 1 1 2 2 2 2 Ssl1-like VWA_2 PF13519.6 KKF94111.1 - 8.6e-07 29.6 0.0 2.1e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KKF94111.1 - 4.6 6.7 7.5 7.4 6.0 7.5 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 Glyoxalase PF00903.25 KKF94112.1 - 1.2e-18 67.5 0.0 5.1e-18 65.5 0.0 1.9 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KKF94112.1 - 2.6e-06 27.7 0.0 9.2e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KKF94112.1 - 0.029 14.5 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Glyoxalase-like domain Ribosomal_L27e PF01777.18 KKF94113.1 - 4e-37 126.4 3.9 6.4e-37 125.8 3.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KKF94113.1 - 0.0026 17.6 1.5 0.0026 17.6 1.5 2.2 2 1 0 2 2 2 1 KOW motif TPT PF03151.16 KKF94114.1 - 3.5e-28 98.8 22.1 4.3e-28 98.5 22.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KKF94114.1 - 4.5e-06 26.9 34.9 0.001 19.3 11.9 2.8 3 0 0 3 3 3 2 EamA-like transporter family Amino_oxidase PF01593.24 KKF94115.1 - 2.5e-10 40.2 0.0 3.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKF94115.1 - 6.6e-09 35.9 0.1 1.5e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKF94115.1 - 5.9e-05 22.4 0.2 0.041 13.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKF94115.1 - 0.0027 17.0 0.3 0.0045 16.3 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKF94115.1 - 0.0037 16.6 0.1 0.0057 15.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKF94115.1 - 0.017 14.4 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KKF94115.1 - 0.057 12.1 0.1 0.094 11.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KKF94115.1 - 0.069 12.2 0.2 0.13 11.3 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KKF94115.1 - 0.075 12.6 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKF94115.1 - 0.14 12.1 0.2 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Gly_transf_sug PF04488.15 KKF94116.1 - 7.5e-14 52.1 0.0 1.5e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cu_amine_oxid PF01179.20 KKF94117.1 - 5.3e-73 246.3 0.0 7e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KKF94117.1 - 0.028 14.7 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain QRPTase_C PF01729.19 KKF94118.1 - 2.3e-54 183.7 0.8 2.9e-54 183.4 0.8 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KKF94118.1 - 1.3e-16 60.4 2.1 1.4e-15 57.1 0.6 2.8 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain TMEM210 PF15195.6 KKF94118.1 - 0.086 13.3 0.2 0.15 12.5 0.2 1.4 1 0 0 1 1 1 0 TMEM210 family FHA PF00498.26 KKF94120.1 - 5.5e-16 58.7 0.1 1.4e-15 57.4 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KKF94120.1 - 0.0013 19.0 0.0 0.004 17.4 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ERM PF00769.19 KKF94120.1 - 3 7.6 33.3 0.078 12.8 26.9 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family SIR2 PF02146.17 KKF94121.1 - 4.4e-54 183.1 0.0 6e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Romo1 PF10247.9 KKF94121.1 - 4.5e-14 52.6 9.5 9.1e-14 51.6 9.5 1.5 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 TPP_enzyme_M PF00205.22 KKF94121.1 - 0.056 13.2 0.0 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Glyco_hydro_3 PF00933.21 KKF94122.1 - 2.3e-60 204.7 0.0 5.4e-60 203.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KKF94122.1 - 0.013 15.7 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Amidohydro_1 PF01979.20 KKF94123.1 - 3e-16 59.7 0.0 8.3e-16 58.2 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKF94123.1 - 1.3e-10 41.4 0.4 4.6e-09 36.3 0.2 2.2 2 0 0 2 2 2 2 Amidohydrolase family NDT80_PhoG PF05224.12 KKF94124.1 - 2.2e-31 109.5 0.0 2.2e-31 109.5 0.0 2.8 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family GREB1 PF15782.5 KKF94124.1 - 0.11 9.6 20.1 0.15 9.2 20.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_23 PF13476.6 KKF94124.1 - 0.49 10.9 7.9 0.81 10.1 7.9 1.3 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.9 KKF94124.1 - 0.5 8.6 34.0 0.65 8.2 34.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GIDA_assoc PF13932.6 KKF94124.1 - 2.9 8.0 8.9 4.9 7.3 8.9 1.3 1 0 0 1 1 1 0 GidA associated domain Glucosamine_iso PF01182.20 KKF94125.1 - 8.6e-18 65.0 0.0 1.8e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NleF_casp_inhib PF16809.5 KKF94126.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NleF caspase inhibitor tRNA-synt_2b PF00587.25 KKF94127.1 - 1.9e-31 109.4 0.0 4.2e-28 98.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKF94127.1 - 4.2e-13 49.2 0.0 7.9e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain SelB-wing_1 PF09105.10 KKF94127.1 - 0.16 12.0 1.0 3.5 7.7 0.1 2.7 2 0 0 2 2 2 0 Elongation factor SelB, winged helix HLH PF00010.26 KKF94128.1 - 3.7e-08 33.2 0.1 7.6e-08 32.2 0.0 1.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Methyltransf_17 PF12692.7 KKF94128.1 - 0.11 12.5 0.2 0.13 12.3 0.2 1.1 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Anoctamin PF04547.12 KKF94129.1 - 2.9e-106 356.0 8.5 3.5e-106 355.7 8.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Pex2_Pex12 PF04757.14 KKF94129.1 - 0.035 13.7 0.1 0.37 10.3 0.1 2.4 2 1 0 2 2 2 0 Pex2 / Pex12 amino terminal region DUF2798 PF11391.8 KKF94129.1 - 4.3 7.4 8.6 12 6.0 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2798) TetR_C_33 PF13305.6 KKF94130.1 - 0.016 16.0 0.2 0.053 14.3 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pex2_Pex12 PF04757.14 KKF94131.1 - 1.4e-47 162.2 3.9 1.9e-47 161.8 3.9 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region 4HBT PF03061.22 KKF94132.1 - 2e-09 37.6 0.0 2.8e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KKF94132.1 - 0.025 14.8 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Gpr1_Fun34_YaaH PF01184.19 KKF94133.1 - 2.4e-31 109.0 21.3 3.2e-31 108.6 21.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pyr_redox_3 PF13738.6 KKF94134.1 - 2.5e-14 53.2 0.1 6.6e-12 45.3 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKF94134.1 - 1.4e-09 37.0 0.5 0.00083 17.9 0.2 3.0 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKF94134.1 - 8e-08 31.9 0.0 0.00029 20.2 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKF94134.1 - 0.00011 22.4 0.0 0.0004 20.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SnoaL_2 PF12680.7 KKF94134.1 - 0.00029 21.4 0.2 0.0056 17.3 0.0 2.5 2 0 0 2 2 2 1 SnoaL-like domain Pyr_redox PF00070.27 KKF94134.1 - 0.00079 19.9 0.1 0.3 11.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKF94134.1 - 0.0027 17.0 0.1 0.02 14.2 0.0 2.2 2 1 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 KKF94134.1 - 0.0044 16.9 0.1 3.6 7.4 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KKF94134.1 - 0.0048 17.1 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.20 KKF94134.1 - 0.0052 16.8 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KKF94134.1 - 0.014 14.1 0.1 0.054 12.2 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KKF94134.1 - 0.022 14.0 0.1 0.56 9.4 0.0 2.8 2 1 1 3 3 3 0 Thi4 family DUF4440 PF14534.6 KKF94134.1 - 0.023 15.1 0.0 0.023 15.1 0.0 2.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4440) 2-Hacid_dh_C PF02826.19 KKF94134.1 - 0.053 12.9 0.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 KKF94134.1 - 0.11 11.7 0.2 37 3.3 0.0 3.2 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KKF94134.1 - 0.13 11.3 0.0 1.1 8.2 0.0 2.4 4 0 0 4 4 4 0 Lycopene cyclase protein RCR PF12273.8 KKF94135.1 - 0.0093 16.6 1.7 0.019 15.6 1.7 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF2370 PF10176.9 KKF94135.1 - 0.067 12.8 0.1 0.2 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) PTP_tm PF18861.1 KKF94135.1 - 0.095 12.7 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J BES1_N PF05687.13 KKF94135.1 - 0.14 12.5 0.2 0.14 12.5 0.2 2.2 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal DUF2457 PF10446.9 KKF94135.1 - 0.37 9.9 5.4 0.57 9.3 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Alpha_GJ PF03229.13 KKF94135.1 - 0.6 10.7 6.1 1.3 9.5 6.1 1.6 1 1 0 1 1 1 0 Alphavirus glycoprotein J Glyco_hydro_11 PF00457.17 KKF94136.1 - 1.2e-76 256.3 16.8 1.4e-76 256.1 16.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF4450 PF14614.6 KKF94136.1 - 0.096 12.2 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) Glyco_hydro_125 PF06824.11 KKF94138.1 - 6.6e-23 81.2 0.0 7.5e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) PI-PLC-X PF00388.19 KKF94139.1 - 0.0037 16.9 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Glyco_hydro_125 PF06824.11 KKF94140.1 - 3.5e-172 573.0 0.0 4e-172 572.8 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DUF917 PF06032.12 KKF94141.1 - 5.1e-106 354.4 0.9 9.5e-106 353.5 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KKF94141.1 - 1.6e-23 83.3 0.2 4e-23 82.0 0.2 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KKF94141.1 - 7.4e-08 32.0 2.6 4.6e-05 22.8 0.4 3.2 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Chromo PF00385.24 KKF94141.1 - 1.5e-06 28.0 0.1 3e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BcrAD_BadFG PF01869.20 KKF94141.1 - 0.0041 16.7 0.1 0.0041 16.7 0.1 1.7 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Ferric_reduct PF01794.19 KKF94142.1 - 1.1e-16 61.1 10.1 1.1e-16 61.1 10.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component PsaM PF07465.13 KKF94142.1 - 0.013 15.2 1.0 0.22 11.2 0.1 2.4 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) NAD_binding_6 PF08030.12 KKF94142.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain PMP1_2 PF08114.11 KKF94142.1 - 0.13 12.1 0.3 0.36 10.6 0.3 1.7 1 0 0 1 1 1 0 ATPase proteolipid family Corona_nucleoca PF00937.18 KKF94143.1 - 5.2 6.0 7.7 6.8 5.6 7.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein VHS PF00790.19 KKF94144.1 - 8.6e-45 152.0 0.0 1.9e-44 151.0 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KKF94144.1 - 6.8e-19 68.0 1.6 1.8e-18 66.6 0.1 2.5 3 0 0 3 3 3 1 GAT domain Alpha_adaptinC2 PF02883.20 KKF94144.1 - 1e-18 67.6 0.0 3.2e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 KKF94144.1 - 3.5e-07 29.7 0.0 9.7e-07 28.3 0.0 1.7 1 0 0 1 1 1 1 GGA N-GAT domain Ribo_biogen_C PF04034.13 KKF94145.1 - 9.7e-36 122.3 0.2 1.6e-27 95.7 0.2 2.2 1 1 1 2 2 2 2 Ribosome biogenesis protein, C-terminal GTP_EFTU PF00009.27 KKF94146.1 - 1.5e-33 116.0 5.2 2.1e-32 112.2 2.4 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KKF94146.1 - 1.7e-25 89.2 0.7 5.3e-25 87.6 0.7 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KKF94146.1 - 9e-11 41.9 0.1 2.1e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 KKF94146.1 - 1.3e-06 28.1 0.3 5.5e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 KKF94146.1 - 7.2e-06 26.0 0.7 0.00097 19.1 0.1 2.5 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU_D2 PF03144.25 KKF94146.1 - 3e-05 24.3 1.8 0.074 13.4 0.0 3.1 2 1 0 2 2 2 2 Elongation factor Tu domain 2 FeoB_N PF02421.18 KKF94146.1 - 5.9e-05 22.6 0.1 0.00022 20.8 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KKF94146.1 - 0.00017 21.1 0.1 0.00044 19.7 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KKF94146.1 - 0.00026 20.5 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 KKF94146.1 - 0.00041 20.1 0.1 0.0014 18.4 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KKF94146.1 - 0.00081 19.6 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KKF94146.1 - 0.19 11.8 4.8 4.3 7.4 0.0 3.1 3 1 1 4 4 4 0 Dynamin family DUF1744 PF08490.12 KKF94147.1 - 1.9e-142 474.6 0.0 2.8e-142 474.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KKF94147.1 - 3.9e-76 256.4 0.6 6.5e-76 255.6 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 KKF94147.1 - 1.9e-08 34.2 0.2 6.6e-08 32.5 0.2 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KKF94147.1 - 3.5e-05 23.8 0.0 0.00012 22.1 0.0 1.9 1 1 0 1 1 1 1 RNase_H superfamily HalOD2 PF18547.1 KKF94147.1 - 0.11 12.4 6.1 1.5 8.8 0.5 2.5 2 0 0 2 2 2 0 Halobacterial output domain 2 DUF4939 PF16297.5 KKF94148.1 - 5.8e-11 42.3 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) TIR_3 PF18567.1 KKF94148.1 - 0.075 13.0 0.5 0.13 12.2 0.5 1.3 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain DHR10 PF18595.1 KKF94148.1 - 0.12 12.5 11.7 0.097 12.7 10.0 1.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain RasGAP_C PF03836.15 KKF94148.1 - 0.12 12.5 3.4 0.23 11.6 3.3 1.5 1 1 0 1 1 1 0 RasGAP C-terminus YicC_N PF03755.13 KKF94148.1 - 0.17 12.4 2.2 0.32 11.4 2.2 1.5 1 0 0 1 1 1 0 YicC-like family, N-terminal region DUF3073 PF11273.8 KKF94148.1 - 0.97 10.2 5.6 1.1 10.0 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) SseC PF04888.12 KKF94148.1 - 2.5 7.6 6.3 3.4 7.2 6.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family YtxH PF12732.7 KKF94148.1 - 5.1 7.7 6.0 9.3 6.9 5.4 1.6 2 0 0 2 2 2 0 YtxH-like protein RT_RNaseH PF17917.1 KKF94149.1 - 2.8e-20 72.6 0.1 4.4e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KKF94149.1 - 4.6e-07 29.8 0.0 1.2e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KKF94149.1 - 4.2e-06 26.4 0.0 5.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Toxin_13 PF07822.11 KKF94151.1 - 0.059 13.5 0.6 1.7e+02 2.4 0.0 4.3 4 0 0 4 4 4 0 Neurotoxin B-IV-like protein AA_permease_2 PF13520.6 KKF94152.1 - 1.1e-79 268.2 28.5 1.4e-79 267.9 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease MIP PF00230.20 KKF94154.1 - 1.1e-19 71.0 2.9 1.4e-19 70.7 2.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein EI24 PF07264.11 KKF94154.1 - 0.014 15.7 1.0 0.018 15.3 1.0 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Zn_ribbon_SprT PF17283.2 KKF94156.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Lgl_C PF08596.10 KKF94158.1 - 7.4e-100 334.4 0.0 6.8e-53 179.8 0.0 2.7 2 1 1 3 3 3 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KKF94158.1 - 4.2e-06 27.4 1.7 0.0036 18.1 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94158.1 - 5.3e-05 23.4 0.0 0.47 10.8 0.0 4.7 5 1 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Suf PF05843.14 KKF94159.1 - 2.6e-59 201.6 19.2 6e-59 200.4 0.0 4.5 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KKF94159.1 - 0.00036 21.1 0.0 0.23 12.4 0.1 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat HrpJ PF07201.11 KKF94159.1 - 0.11 12.8 2.8 6.1 7.1 0.1 3.1 3 0 0 3 3 3 0 HrpJ-like domain ASF1_hist_chap PF04729.13 KKF94160.1 - 4.1e-70 234.7 0.0 5.4e-70 234.3 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone RasGAP PF00616.19 KKF94161.1 - 6.4e-60 202.4 0.0 2e-59 200.8 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KKF94161.1 - 2.4e-29 102.2 4.4 2.4e-29 102.2 4.4 2.6 2 1 1 3 3 3 1 RasGAP C-terminus CENP-F_leu_zip PF10473.9 KKF94161.1 - 4.8 7.2 10.8 0.27 11.2 2.9 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dict-STAT-coil PF09267.10 KKF94161.1 - 6.4 7.2 8.4 0.3 11.5 1.2 2.6 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil Myb_DNA-binding PF00249.31 KKF94162.1 - 0.0014 18.8 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKF94162.1 - 0.0027 17.9 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 KKF94162.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 SLIDE RdRP PF05183.12 KKF94163.1 - 2.7e-175 584.4 0.0 3.5e-175 584.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase FAD-oxidase_C PF02913.19 KKF94163.1 - 3.8e-62 210.2 0.3 6.2e-62 209.5 0.3 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Ribosomal_S4e PF00900.20 KKF94163.1 - 4.9e-36 122.5 1.8 1.1e-35 121.3 0.4 2.4 2 0 0 2 2 2 1 Ribosomal family S4e FAD_binding_4 PF01565.23 KKF94163.1 - 2.2e-33 114.9 0.0 8.9e-33 113.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain 40S_S4_C PF16121.5 KKF94163.1 - 1.6e-22 78.8 0.1 3.1e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KKF94163.1 - 5.8e-18 64.7 6.7 1.3e-17 63.6 6.7 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 KKF94163.1 - 0.00025 20.9 0.4 0.00076 19.3 0.4 1.9 1 0 0 1 1 1 1 KOW motif S4 PF01479.25 KKF94163.1 - 0.0042 16.8 0.0 0.0091 15.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain Legionella_OMP PF05150.12 KKF94163.1 - 0.044 12.7 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor 2OG-FeII_Oxy_3 PF13640.6 KKF94164.1 - 4e-11 43.7 0.0 5.7e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AJAP1_PANP_C PF15298.6 KKF94165.1 - 0.032 14.5 0.3 0.051 13.8 0.3 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus UL42 PF17638.2 KKF94165.1 - 7.7 6.5 10.6 0.074 13.0 2.3 1.8 2 0 0 2 2 2 0 HCMV UL42 Fumble PF03630.14 KKF94166.1 - 9.9e-143 475.3 0.1 1.3e-142 474.9 0.1 1.1 1 0 0 1 1 1 1 Fumble LAP1C PF05609.12 KKF94167.1 - 0.04 13.0 0.6 0.5 9.4 1.4 1.9 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) SLAC1 PF03595.17 KKF94168.1 - 1.1e-87 294.3 49.5 1.3e-87 294.1 49.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4820 PF16091.5 KKF94169.1 - 0.11 11.8 0.9 0.11 11.9 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Astro_capsid_p PF12226.8 KKF94169.1 - 0.14 11.3 5.0 0.14 11.3 5.0 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 KKF94169.1 - 0.47 9.7 13.5 0.55 9.5 13.5 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KKF94169.1 - 1 7.6 8.5 1.1 7.5 8.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Fmp27 PF10344.9 KKF94169.1 - 1.2 7.1 2.5 1.4 6.9 2.5 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 FAM176 PF14851.6 KKF94169.1 - 4.3 7.0 9.2 5.4 6.7 9.2 1.2 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 KKF94169.1 - 7 4.6 6.1 7.1 4.6 6.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spb1_C PF07780.12 KKF94171.1 - 7.8e-81 270.7 21.2 7.8e-81 270.7 21.2 3.8 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 KKF94171.1 - 1.5e-57 194.6 0.0 2.6e-57 193.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KKF94171.1 - 4.6e-50 169.7 6.1 4.6e-50 169.7 6.1 5.4 4 2 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KKF94171.1 - 0.0037 17.1 0.0 0.022 14.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain WD40 PF00400.32 KKF94172.1 - 2.6e-09 37.5 1.5 0.12 13.3 0.2 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94172.1 - 6.1e-05 23.2 0.0 6 7.2 0.0 4.3 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKF94172.1 - 0.0078 16.1 0.0 0.57 10.0 0.0 2.2 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A EamA PF00892.20 KKF94174.1 - 9.5e-09 35.5 34.7 6.7e-07 29.6 3.3 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 KKF94174.1 - 1.3e-07 31.4 3.4 3.4e-07 30.0 1.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 KKF94174.1 - 8.8e-07 28.4 0.3 8.8e-07 28.4 0.3 1.9 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 KKF94174.1 - 0.0013 18.3 7.5 0.0013 18.3 7.5 1.8 2 1 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 KKF94174.1 - 0.004 16.4 8.9 0.004 16.4 8.9 1.6 2 0 0 2 2 2 1 UAA transporter family Ras PF00071.22 KKF94175.1 - 4e-56 189.1 0.0 4.7e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF94175.1 - 7.1e-32 110.2 0.0 9.9e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF94175.1 - 3.8e-13 49.3 0.0 5e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKF94175.1 - 5.5e-08 32.9 0.0 8.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKF94175.1 - 8.9e-06 25.2 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKF94175.1 - 0.0001 22.3 0.1 0.0038 17.2 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KKF94175.1 - 0.00018 21.1 0.1 0.0074 15.9 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKF94175.1 - 0.0029 17.1 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KKF94175.1 - 0.0038 17.6 0.0 0.0065 16.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KKF94175.1 - 0.0039 17.2 0.0 0.0097 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KKF94175.1 - 0.0042 16.8 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KKF94175.1 - 0.0091 16.3 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 KKF94175.1 - 0.019 14.3 0.1 0.065 12.5 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 KKF94175.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KKF94175.1 - 0.024 14.2 0.0 0.067 12.8 0.0 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KKF94175.1 - 0.03 13.8 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KKF94175.1 - 0.031 14.1 0.2 0.96 9.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 KKF94175.1 - 0.069 13.0 0.2 0.14 12.1 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KKF94175.1 - 0.082 12.1 0.1 0.17 11.0 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain MCM PF00493.23 KKF94175.1 - 0.087 11.9 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain FeoB_N PF02421.18 KKF94175.1 - 0.1 12.1 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.15 KKF94175.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 KKF94175.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 KKF94175.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_lid_2 PF17863.1 KKF94176.1 - 2.1e-06 27.4 0.2 2.1e-06 27.4 0.2 2.2 2 0 0 2 2 2 1 AAA lid domain GDA1_CD39 PF01150.17 KKF94177.1 - 1.8e-102 343.2 0.0 2.2e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KKF94177.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family ATP-synt_ab PF00006.25 KKF94178.1 - 1.9e-110 367.6 0.0 2.5e-110 367.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KKF94178.1 - 5.9e-47 158.5 0.1 1.8e-46 156.9 0.0 1.9 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KKF94178.1 - 2e-14 53.9 4.2 4.9e-14 52.6 4.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain SURF2 PF05477.11 KKF94180.1 - 0.12 12.1 5.6 0.27 10.9 5.6 1.6 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TruB_N PF01509.18 KKF94181.1 - 4.7e-46 156.9 0.0 1.1e-45 155.6 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KKF94181.1 - 2.3e-06 27.6 0.0 5.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PI3K_1B_p101 PF10486.9 KKF94181.1 - 0.063 11.1 1.5 0.093 10.5 1.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit D5_N PF08706.11 KKF94181.1 - 0.07 13.4 0.5 14 6.0 0.0 2.6 2 0 0 2 2 2 0 D5 N terminal like Nkap_C PF06047.11 KKF94181.1 - 0.94 9.6 5.0 0.33 11.1 0.2 2.3 2 0 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain Sec2p PF06428.11 KKF94183.1 - 4.2e-11 42.7 6.9 4.2e-11 42.7 6.9 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p zf-ribbon_3 PF13248.6 KKF94183.1 - 0.019 14.4 1.1 0.032 13.6 1.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Lzipper-MIP1 PF14389.6 KKF94183.1 - 0.037 14.3 5.5 4.7 7.6 0.4 3.5 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Cys_rich_CPXG PF14255.6 KKF94183.1 - 0.07 13.0 0.4 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG SlyX PF04102.12 KKF94183.1 - 0.1 13.2 0.2 0.1 13.2 0.2 3.4 3 1 0 3 3 3 0 SlyX DUF4763 PF15960.5 KKF94183.1 - 0.15 11.4 3.9 2.3 7.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Jnk-SapK_ap_N PF09744.9 KKF94183.1 - 0.2 11.9 7.7 1.1 9.5 4.7 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CLZ PF16526.5 KKF94183.1 - 0.37 11.2 7.7 4.3 7.8 0.1 3.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels XhlA PF10779.9 KKF94183.1 - 0.42 10.8 1.8 13 6.0 0.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA HAUS-augmin3 PF14932.6 KKF94183.1 - 0.61 9.6 4.9 1.2 8.6 2.1 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 BST2 PF16716.5 KKF94183.1 - 0.79 10.4 5.8 3.3 8.4 0.0 2.9 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 ABC_tran_CTD PF16326.5 KKF94183.1 - 1.4 9.2 8.4 5 7.5 0.1 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF2630 PF10944.8 KKF94183.1 - 2 8.9 13.3 0.24 11.9 2.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2630) TolA_bind_tri PF16331.5 KKF94183.1 - 7.2 6.8 11.7 6 7.0 1.1 2.7 3 0 0 3 3 3 0 TolA binding protein trimerisation HalX PF08663.10 KKF94183.1 - 9 6.7 10.0 7.4 7.0 0.2 3.0 2 1 1 3 3 3 0 HalX domain EXOSC1 PF10447.9 KKF94184.1 - 8.9e-20 71.3 1.6 8.1e-14 52.2 0.3 2.4 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KKF94184.1 - 7.6e-12 44.8 1.8 9e-12 44.6 0.7 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region PCB_OB PF17092.5 KKF94184.1 - 0.014 16.1 0.5 0.027 15.2 0.4 1.5 1 1 0 1 1 1 0 Penicillin-binding protein OB-like domain S1 PF00575.23 KKF94184.1 - 0.044 14.1 0.2 0.31 11.4 0.2 2.2 1 1 0 1 1 1 0 S1 RNA binding domain ERG2_Sigma1R PF04622.12 KKF94185.1 - 3.5e-92 307.5 0.2 4.2e-92 307.2 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UCR_6-4kD PF08997.10 KKF94185.1 - 0.092 12.7 0.8 1.1 9.2 0.1 2.9 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein PTR2 PF00854.21 KKF94186.1 - 1.9e-72 244.3 3.5 2.9e-72 243.7 3.5 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KKF94186.1 - 2.2e-09 36.7 19.1 9e-08 31.4 20.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily NmrA PF05368.13 KKF94187.1 - 1.5e-74 250.5 0.0 1.9e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKF94187.1 - 4.4e-06 26.7 0.0 1.9e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding DUF3798 PF12683.7 KKF94187.1 - 0.0057 16.1 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3798) Fcf1 PF04900.12 KKF94188.1 - 2.1e-34 117.8 0.6 3.6e-34 117.1 0.2 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KKF94188.1 - 5.7e-14 52.4 0.8 9e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 PIN like domain LPD7 PF18821.1 KKF94188.1 - 0.064 13.4 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 Apt1 PF10351.9 KKF94189.1 - 0.0031 16.4 5.8 0.0045 15.9 5.8 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain ABC_tran PF00005.27 KKF94190.1 - 4.3e-37 127.7 0.1 5e-27 95.1 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKF94190.1 - 1.9e-27 96.6 24.7 6.8e-16 58.7 5.2 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region Zeta_toxin PF06414.12 KKF94190.1 - 5.8e-06 25.7 0.0 0.00011 21.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KKF94190.1 - 6.2e-06 26.7 0.1 0.034 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KKF94190.1 - 1.7e-05 24.8 2.2 0.035 14.2 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KKF94190.1 - 6e-05 22.6 5.9 0.23 10.9 0.8 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKF94190.1 - 0.00011 21.9 1.1 0.43 10.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKF94190.1 - 0.00019 21.4 0.9 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KKF94190.1 - 0.00035 20.3 1.8 0.15 11.8 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KKF94190.1 - 0.00051 19.9 2.5 0.34 10.7 0.2 2.8 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 KKF94190.1 - 0.00075 18.6 0.4 0.3 10.0 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KKF94190.1 - 0.00078 20.0 2.9 0.24 11.9 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KKF94190.1 - 0.0021 18.3 1.7 3.2 8.0 0.3 3.4 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KKF94190.1 - 0.0045 17.2 0.7 0.2 11.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 KKF94190.1 - 0.0047 15.9 0.7 0.4 9.5 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 KKF94190.1 - 0.0092 16.2 0.2 2.2 8.5 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KKF94190.1 - 0.027 14.2 0.2 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KKF94190.1 - 0.037 13.5 0.5 2.9 7.4 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KKF94190.1 - 0.058 13.5 4.7 0.36 10.9 0.5 2.6 2 0 0 2 2 2 0 Dynamin family PhoH PF02562.16 KKF94190.1 - 0.068 12.6 0.2 0.41 10.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 KKF94190.1 - 0.093 12.5 0.1 4.1 7.1 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 KKF94190.1 - 0.11 13.1 0.1 17 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KKF94190.1 - 0.13 12.3 8.7 0.12 12.5 0.5 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KKF94190.1 - 0.14 12.6 0.1 36 4.8 0.1 2.7 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 KKF94190.1 - 0.15 11.6 0.1 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KKF94190.1 - 0.17 11.6 0.2 12 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKF94190.1 - 0.18 11.8 0.3 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KKF94190.1 - 0.19 11.6 2.1 0.91 9.4 0.3 2.3 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 KKF94190.1 - 0.2 11.4 0.5 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KKF94190.1 - 0.47 10.0 2.9 0.6 9.7 0.4 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain cobW PF02492.19 KKF94191.1 - 7.6e-40 136.4 0.0 1.4e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KKF94191.1 - 2.3e-05 24.3 0.0 5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 KKF94191.1 - 0.0029 17.5 0.1 2.8 7.8 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 KKF94191.1 - 0.0085 16.4 0.1 0.098 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KKF94191.1 - 0.0089 15.8 0.6 0.022 14.5 0.0 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF463 PF04317.12 KKF94191.1 - 0.0092 15.0 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 1 YcjX-like family, DUF463 AAA_29 PF13555.6 KKF94191.1 - 0.045 13.5 0.3 0.73 9.6 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2075 PF09848.9 KKF94191.1 - 0.057 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KKF94191.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KKF94191.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 KKF94191.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain GCP_N_terminal PF17681.1 KKF94192.1 - 3.8e-36 125.3 0.5 5.8e-36 124.7 0.5 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KKF94192.1 - 3.2e-27 95.8 1.2 3.2e-27 95.8 1.2 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KKF94192.1 - 3.8e-09 35.5 0.9 7.7e-09 34.5 0.6 1.6 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.16 KKF94193.1 - 1.3e-116 389.4 8.6 1.6e-116 389.1 8.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase 6PF2K PF01591.18 KKF94194.1 - 8.1e-59 198.6 0.0 1.2e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KKF94194.1 - 5.7e-22 78.4 0.4 1.5e-21 77.0 0.4 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KKF94194.1 - 0.044 14.0 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Porin_3 PF01459.22 KKF94195.1 - 4.8e-83 278.7 0.1 5.7e-83 278.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin tRNA-synt_1_2 PF13603.6 KKF94196.1 - 1.6e-43 148.4 0.0 3.5e-43 147.3 0.0 1.6 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 KKF94196.1 - 4e-38 131.0 0.0 2e-17 62.7 0.0 5.6 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKF94196.1 - 4e-12 46.3 0.0 7.7e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKF94196.1 - 1.9e-09 36.8 1.2 0.18 10.5 0.0 4.4 3 1 1 4 4 4 4 tRNA synthetases class I (M) MTHFR PF02219.17 KKF94197.1 - 1.4e-101 339.6 0.0 2.2e-101 339.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PAPA-1 PF04795.12 KKF94197.1 - 0.098 13.5 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 PAPA-1-like conserved region Pkinase_fungal PF17667.1 KKF94199.1 - 2.4e-62 211.0 0.2 3e-62 210.7 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Myb_DNA-binding PF00249.31 KKF94200.1 - 2.2e-15 56.6 1.6 8.5e-09 35.5 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKF94200.1 - 3.4e-11 43.2 0.5 2.3e-05 24.5 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Suf PF05843.14 KKF94200.1 - 0.24 11.4 15.5 0.43 10.5 15.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 KKF94200.1 - 7.6 4.7 17.7 7.6 4.7 17.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Myb_DNA-binding PF00249.31 KKF94201.1 - 0.00075 19.6 0.6 0.0057 16.8 0.2 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKF94201.1 - 0.0016 18.7 0.1 0.021 15.1 0.3 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain ILVD_EDD PF00920.21 KKF94202.1 - 2.6e-207 689.6 0.6 3e-207 689.4 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family Glyco_transf_15 PF01793.16 KKF94203.1 - 2.3e-95 319.6 12.4 1.6e-94 316.8 12.4 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Rhabdo_ncap_2 PF03216.13 KKF94203.1 - 0.17 11.4 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleoprotein DUF4604 PF15377.6 KKF94204.1 - 2.7e-30 106.1 11.5 3.1e-30 105.9 11.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) COX5B PF01215.19 KKF94205.1 - 7.4e-53 177.7 0.0 9.1e-53 177.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 KKF94205.1 - 0.017 15.2 0.2 0.026 14.6 0.2 1.3 1 0 0 1 1 1 0 Zinc-finger domain Ribosomal_L27A PF00828.19 KKF94206.1 - 6.6e-31 107.6 0.2 9.3e-31 107.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sec34 PF04136.15 KKF94208.1 - 0.0099 15.8 1.9 0.022 14.6 0.8 2.0 2 0 0 2 2 2 1 Sec34-like family Atg14 PF10186.9 KKF94208.1 - 0.067 12.3 1.9 0.097 11.7 1.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V-SNARE_C PF12352.8 KKF94208.1 - 0.085 13.2 0.7 0.19 12.0 0.1 2.0 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DivIC PF04977.15 KKF94208.1 - 0.16 11.8 2.0 0.45 10.3 2.0 1.7 1 0 0 1 1 1 0 Septum formation initiator OHCU_decarbox PF09349.10 KKF94209.1 - 2.1e-49 167.9 0.2 2.4e-49 167.8 0.2 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Prp19 PF08606.11 KKF94210.1 - 3.6e-32 110.2 3.1 7.4e-32 109.2 3.1 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 KKF94210.1 - 6.8e-10 39.4 0.0 0.0025 18.6 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94210.1 - 5.9e-08 32.9 0.0 0.14 12.4 0.0 4.5 1 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 KKF94210.1 - 0.0012 17.9 0.0 0.29 10.1 0.0 2.2 2 0 0 2 2 2 2 VID27 C-terminal WD40-like domain V_ATPase_I_N PF18670.1 KKF94210.1 - 0.012 16.0 0.6 0.035 14.5 0.2 1.9 2 0 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain VPS9 PF02204.18 KKF94210.1 - 0.017 15.3 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain zf-Nse PF11789.8 KKF94210.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Frtz PF11768.8 KKF94210.1 - 0.029 12.7 0.0 0.085 11.2 0.0 1.6 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Mcl1_mid PF12341.8 KKF94210.1 - 0.067 12.5 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Ge1_WD40 PF16529.5 KKF94210.1 - 0.14 11.0 0.0 0.3 10.0 0.0 1.4 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eRF1_1 PF03463.15 KKF94212.1 - 2.9e-16 59.6 0.0 3e-15 56.4 0.0 2.2 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.15 KKF94212.1 - 5.9e-08 33.1 0.0 1e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KKF94212.1 - 5.2e-05 23.7 0.0 0.00024 21.6 0.0 2.1 2 0 0 2 2 2 1 eRF1 domain 3 CAF1C_H4-bd PF12265.8 KKF94213.1 - 4.8e-15 55.6 0.0 1.5e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KKF94213.1 - 8.3e-15 54.9 11.2 9.2e-08 32.6 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94213.1 - 3.5e-09 36.8 3.8 0.001 19.4 0.2 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3246 PF11596.8 KKF94213.1 - 0.99 8.8 4.9 0.22 10.9 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Thioredoxin PF00085.20 KKF94214.1 - 4.8e-27 94.0 0.0 6.2e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KKF94214.1 - 2e-11 44.3 0.1 5.6e-10 39.7 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KKF94214.1 - 2.9e-07 30.1 0.0 3.1e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KKF94214.1 - 5.9e-07 29.7 0.0 0.0054 17.0 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KKF94214.1 - 1.6e-05 24.9 0.0 2.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KKF94214.1 - 5.2e-05 23.0 0.0 6.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KKF94214.1 - 0.0036 17.2 0.1 0.055 13.4 0.1 2.0 1 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_3 PF13192.6 KKF94214.1 - 0.012 15.6 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin domain Glutaredoxin PF00462.24 KKF94214.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin Redoxin PF08534.10 KKF94214.1 - 0.013 15.2 0.2 0.24 11.1 0.1 2.1 1 1 1 2 2 2 0 Redoxin HyaE PF07449.11 KKF94214.1 - 0.016 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 KKF94214.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_6 PF13848.6 KKF94214.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain WD40 PF00400.32 KKF94215.1 - 2.9e-29 100.7 8.7 1e-05 26.2 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94215.1 - 1.8e-05 25.0 0.0 0.17 12.2 0.0 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF94215.1 - 0.00018 20.6 0.1 0.041 12.8 0.0 3.1 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PTCB-BRCT PF12738.7 KKF94216.1 - 1.5e-36 124.2 0.0 9.2e-19 67.2 0.0 3.3 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 KKF94216.1 - 6.3e-31 106.6 0.0 1.7e-11 44.3 0.0 4.3 3 1 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKF94216.1 - 2.8e-16 59.7 0.0 4.6e-06 27.0 0.0 3.9 3 1 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KKF94216.1 - 1.2e-07 31.9 0.0 0.0022 18.3 0.0 3.3 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KKF94216.1 - 0.026 14.6 0.1 3.4 7.8 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Cullin_binding PF03556.15 KKF94217.1 - 1.4e-32 112.7 3.6 2.2e-32 112.0 3.6 1.3 1 0 0 1 1 1 1 Cullin binding Ribosomal_S6 PF01250.17 KKF94218.1 - 1.7e-23 82.7 0.0 2e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 SNF2_N PF00176.23 KKF94219.1 - 2.1e-73 247.1 0.0 2.9e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SQS_PSY PF00494.19 KKF94219.1 - 1.6e-38 132.7 1.2 3.5e-38 131.6 1.2 1.5 1 0 0 1 1 1 1 Squalene/phytoene synthase HIRAN PF08797.11 KKF94219.1 - 8.3e-22 76.9 0.1 1.6e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KKF94219.1 - 6.1e-15 55.5 0.0 1.5e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KKF94219.1 - 2.1e-05 24.3 9.5 4e-05 23.4 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKF94219.1 - 2.9e-05 23.8 5.8 7.1e-05 22.6 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKF94219.1 - 7e-05 22.6 7.6 0.00012 21.9 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKF94219.1 - 0.0012 19.1 9.3 0.0026 18.0 9.3 1.6 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.15 KKF94219.1 - 0.0036 17.3 0.0 0.01 15.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KKF94219.1 - 0.011 15.6 9.1 0.027 14.4 8.9 1.8 2 0 0 2 2 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKF94219.1 - 0.021 14.9 8.3 0.043 13.8 8.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger UBA_4 PF14555.6 KKF94219.1 - 0.022 14.6 0.1 0.064 13.1 0.1 1.8 1 0 0 1 1 1 0 UBA-like domain ERCC3_RAD25_C PF16203.5 KKF94219.1 - 0.045 13.0 0.3 0.081 12.1 0.3 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-ANAPC11 PF12861.7 KKF94219.1 - 0.37 10.9 2.4 0.78 9.8 2.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KKF94219.1 - 8.8 6.6 7.8 18 5.6 7.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Sugar_tr PF00083.24 KKF94221.1 - 1.4e-129 432.9 31.1 1.7e-129 432.6 31.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF94221.1 - 5.1e-17 61.8 41.0 6.1e-14 51.7 27.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily RVT_1 PF00078.27 KKF94222.1 - 3e-08 33.5 0.1 5e-07 29.5 0.1 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAO PF01266.24 KKF94224.1 - 3.8e-50 171.4 0.1 4.5e-50 171.2 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKF94224.1 - 8.8e-05 22.5 0.2 0.0043 17.0 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KKF94224.1 - 0.00012 20.9 0.0 0.011 14.4 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 KKF94224.1 - 0.00023 21.4 0.1 0.00078 19.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKF94224.1 - 0.016 14.3 0.5 0.15 11.1 0.5 2.0 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KKF94224.1 - 0.018 14.3 0.0 0.071 12.4 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2625 PF10946.8 KKF94224.1 - 0.035 13.2 0.3 0.86 8.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF2625 Trp_halogenase PF04820.14 KKF94224.1 - 0.039 12.8 0.2 0.055 12.3 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KKF94224.1 - 0.079 12.2 0.2 1.1 8.4 0.0 2.4 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MoeA_N PF03453.17 KKF94224.1 - 0.13 12.1 0.1 16 5.2 0.0 2.4 2 1 0 2 2 2 0 MoeA N-terminal region (domain I and II) K_oxygenase PF13434.6 KKF94224.1 - 0.13 11.4 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KKF94224.1 - 0.18 11.0 0.1 0.32 10.2 0.1 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Methyltransf_23 PF13489.6 KKF94225.1 - 1.1e-24 87.2 0.0 4e-24 85.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF94225.1 - 7.4e-11 42.7 0.3 1.2e-09 38.8 0.0 3.0 4 1 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF94225.1 - 8.8e-11 41.8 0.0 1.1e-09 38.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF94225.1 - 2.1e-10 41.2 0.0 9.2e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF94225.1 - 3.3e-08 34.0 0.0 1.3e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KKF94225.1 - 8.3e-05 22.8 0.0 0.00029 21.0 0.0 1.8 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KKF94225.1 - 0.0063 16.0 0.0 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KKF94225.1 - 0.014 14.7 0.0 0.14 11.5 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KKF94225.1 - 0.028 14.0 0.0 0.099 12.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.12 KKF94225.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Terpene_synth_C PF03936.16 KKF94225.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain F-box-like PF12937.7 KKF94226.1 - 0.00061 19.6 0.2 0.0022 17.8 0.2 2.0 1 0 0 1 1 1 1 F-box-like PDGF_N PF04692.13 KKF94226.1 - 0.07 13.9 0.0 0.16 12.8 0.0 1.5 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region RCC1 PF00415.18 KKF94228.1 - 8.4e-65 215.2 5.9 5.1e-09 36.6 0.2 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KKF94228.1 - 3.5e-39 131.8 22.5 2e-09 37.0 0.4 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 KKF94228.1 - 0.0021 17.9 0.0 0.17 11.9 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Peptidase_C25_C PF03785.14 KKF94228.1 - 0.015 15.1 0.2 9.3 6.2 0.1 3.1 3 0 0 3 3 3 0 Peptidase family C25, C terminal ig-like domain Hira PF07569.11 KKF94228.1 - 0.056 13.2 0.0 15 5.2 0.0 4.2 4 2 1 5 5 5 0 TUP1-like enhancer of split Pam16 PF03656.13 KKF94229.1 - 1.1e-27 96.5 0.1 1.3e-27 96.3 0.1 1.0 1 0 0 1 1 1 1 Pam16 HrpB2 PF09487.10 KKF94229.1 - 0.023 15.1 0.1 0.038 14.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) 4HBT PF03061.22 KKF94230.1 - 3.8e-14 52.8 0.0 5.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KKF94230.1 - 0.0041 17.2 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 KKF94230.1 - 0.079 13.2 0.0 0.085 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Tfb2 PF03849.14 KKF94231.1 - 1.7e-125 418.7 0.0 2e-125 418.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KKF94231.1 - 3e-20 72.4 2.8 3.2e-20 72.3 0.6 2.1 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KKF94231.1 - 0.00013 22.1 0.1 0.00036 20.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TANGO2 PF05742.12 KKF94232.1 - 2.2e-64 218.0 0.0 2.5e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 HgmA PF04209.13 KKF94233.1 - 1.4e-186 620.3 0.1 1.7e-186 620.1 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Fungal_trans PF04082.18 KKF94235.1 - 1.5e-10 40.6 0.0 1.5e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF94235.1 - 9.5e-08 32.0 8.6 1.7e-07 31.2 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CobT PF06213.12 KKF94235.1 - 0.073 12.5 5.9 0.17 11.3 5.9 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peptidase_S49_N PF08496.10 KKF94235.1 - 0.62 10.1 3.0 1.8 8.6 3.0 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4407 PF14362.6 KKF94235.1 - 0.73 9.1 5.3 0.98 8.7 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MctB PF11382.8 KKF94235.1 - 4.6 6.9 7.0 0.72 9.5 2.8 1.7 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB G0-G1_switch_2 PF15103.6 KKF94235.1 - 4.8 7.7 5.9 0.58 10.6 1.1 1.9 2 0 0 2 2 2 0 G0/G1 switch protein 2 Lipase_GDSL_2 PF13472.6 KKF94236.1 - 3.8e-14 53.5 0.1 4.9e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKF94236.1 - 0.0015 18.6 0.4 0.0069 16.4 0.4 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PCI PF01399.27 KKF94237.1 - 6.6e-12 45.9 0.0 1.5e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KKF94237.1 - 0.17 11.6 0.7 0.63 9.7 0.0 2.3 2 1 0 2 2 2 0 26S proteasome subunit RPN7 HSCB_C PF07743.13 KKF94238.1 - 2.7e-19 69.4 6.1 3.6e-19 69.0 6.1 1.2 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DUF3576 PF12100.8 KKF94238.1 - 0.025 14.7 0.2 0.035 14.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) AvrPto PF11592.8 KKF94238.1 - 0.029 14.4 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto tRNA-synt_1c_C PF03950.18 KKF94238.1 - 0.041 13.8 0.1 0.059 13.3 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain DUF4936 PF16290.5 KKF94238.1 - 0.064 13.9 0.9 0.19 12.5 0.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4936) DUF3712 PF12505.8 KKF94239.1 - 5.7e-25 88.0 3.6 1.1e-24 87.0 3.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) HCNGP PF07818.13 KKF94240.1 - 5.9e-23 81.3 1.1 9.2e-23 80.7 0.2 1.7 2 0 0 2 2 2 1 HCNGP-like protein DEAD PF00270.29 KKF94241.1 - 6.2e-51 172.6 0.0 1.4e-49 168.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF94241.1 - 1.7e-27 96.0 0.0 1.9e-26 92.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF94241.1 - 0.017 15.1 0.0 0.066 13.2 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KKF94242.1 - 1.8e-44 151.6 0.9 2.9e-44 150.9 0.9 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF94242.1 - 3.6e-32 111.0 0.5 6.9e-31 106.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF94242.1 - 4.5e-06 26.8 0.0 7.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KKF94242.1 - 5.4e-05 23.0 0.2 0.00011 21.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF94242.1 - 0.0007 20.0 0.4 0.0046 17.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKF94242.1 - 0.0095 16.2 0.5 0.046 14.0 0.5 2.1 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 KKF94242.1 - 0.021 14.2 0.2 0.052 12.9 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 KKF94242.1 - 0.027 14.4 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KKF94242.1 - 0.089 12.6 0.1 0.17 11.7 0.1 1.6 1 1 0 1 1 1 0 Helicase fragilysinNterm PF16376.5 KKF94242.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin Cupin_8 PF13621.6 KKF94243.1 - 1.6e-16 60.8 0.1 2.4e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KKF94243.1 - 5.7e-10 39.6 0.1 3.3e-09 37.2 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KKF94243.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein DUF1771 PF08590.10 KKF94244.1 - 2.6e-15 56.5 12.2 2.6e-15 56.5 12.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KKF94244.1 - 5.3e-08 32.7 6.5 2.6e-05 24.1 0.3 2.9 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 KKF94244.1 - 1.1e-06 28.9 0.0 3.1e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 KKF94244.1 - 3.4e-06 26.8 2.2 0.0039 17.1 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KKF94244.1 - 1.2e-05 25.0 10.1 0.0002 21.1 0.3 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KKF94244.1 - 5.8e-05 23.4 4.2 0.058 13.9 0.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger HBS1_N PF08938.10 KKF94244.1 - 0.0025 18.1 0.0 0.007 16.6 0.0 1.7 1 0 0 1 1 1 1 HBS1 N-terminus zf-CCCH_3 PF15663.5 KKF94244.1 - 0.049 13.8 1.6 3.6 7.9 0.1 2.4 1 1 1 2 2 2 0 Zinc-finger containing family Torus PF16131.5 KKF94244.1 - 0.12 13.1 4.0 3.8 8.2 0.3 2.6 1 1 1 2 2 2 0 Torus domain SNARE_assoc PF09335.11 KKF94245.1 - 0.00027 21.4 6.4 0.00027 21.4 6.4 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF4134 PF13572.6 KKF94245.1 - 0.0052 17.1 1.4 2.2 8.6 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4134) TPR_6 PF13174.6 KKF94245.1 - 0.58 10.9 2.1 1.5 9.6 2.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 KKF94246.1 - 2e-09 37.5 0.0 3.6e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKF94246.1 - 9.3e-06 25.1 0.0 2.2e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKF94246.1 - 0.00037 21.2 0.0 0.0011 19.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KKF94246.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase BshC PF10079.9 KKF94247.1 - 0.13 11.0 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Hormone_3 PF00159.18 KKF94247.1 - 0.14 12.2 0.5 4.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Pancreatic hormone peptide Glyco_hydro_20 PF00728.22 KKF94248.1 - 1.6e-87 294.2 0.0 2.1e-87 293.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KKF94248.1 - 1.5e-23 84.0 0.0 3.7e-23 82.7 0.0 1.7 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KKF94248.1 - 2.5e-07 31.5 0.0 2e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 ABC1 PF03109.16 KKF94249.1 - 2.6e-23 82.5 0.0 1.9e-14 53.9 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 KKF94249.1 - 0.017 15.1 0.4 0.13 12.2 0.4 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cyto_heme_lyase PF01265.17 KKF94250.1 - 3.7e-117 391.1 0.3 7.9e-117 390.0 0.3 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase MbeD_MobD PF04899.12 KKF94251.1 - 0.14 12.3 0.2 0.33 11.1 0.2 1.7 2 0 0 2 2 2 0 MbeD/MobD like ABC2_membrane PF01061.24 KKF94252.1 - 3e-75 252.2 67.9 2.6e-41 141.4 28.4 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKF94252.1 - 1e-34 120.0 0.0 3.6e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKF94252.1 - 2.7e-24 84.9 6.1 4.2e-21 74.7 0.0 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KKF94252.1 - 1.2e-13 51.4 0.1 4.8e-13 49.5 0.1 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KKF94252.1 - 4.6e-07 29.3 48.5 0.00022 20.4 26.7 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 KKF94252.1 - 9.8e-07 29.0 0.1 0.012 15.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KKF94252.1 - 3.1e-06 27.7 0.1 0.009 16.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KKF94252.1 - 9.6e-06 25.6 0.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KKF94252.1 - 2e-05 24.6 0.0 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KKF94252.1 - 2.2e-05 24.1 0.1 0.0075 16.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KKF94252.1 - 5.8e-05 22.8 0.2 0.00054 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKF94252.1 - 0.00022 21.8 0.0 0.035 14.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KKF94252.1 - 0.00051 20.5 0.0 0.036 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KKF94252.1 - 0.00058 19.4 0.1 0.49 9.8 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KKF94252.1 - 0.0075 16.5 0.1 0.066 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKF94252.1 - 0.0085 16.4 0.1 0.81 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKF94252.1 - 0.048 13.6 0.9 6.4 6.7 0.1 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KKF94252.1 - 0.049 13.2 2.4 0.15 11.6 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KKF94252.1 - 0.054 13.6 0.1 13 5.9 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KKF94252.1 - 0.076 12.7 0.7 2.7 7.6 0.2 2.5 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KKF94252.1 - 0.15 11.4 0.0 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain FtsK_SpoIIIE PF01580.18 KKF94252.1 - 0.17 11.2 0.4 9.2 5.5 0.1 3.0 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KKF94252.1 - 0.2 12.2 0.4 0.49 10.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Methyltransf_16 PF10294.9 KKF94253.1 - 5.8e-31 107.6 0.0 3.2e-17 62.8 0.0 2.2 1 1 1 2 2 2 2 Lysine methyltransferase MTS PF05175.14 KKF94253.1 - 0.00071 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KKF94253.1 - 0.029 14.2 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KKF94253.1 - 0.031 15.0 0.0 0.13 13.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KKF94253.1 - 0.07 13.8 0.0 0.22 12.3 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain dCMP_cyt_deam_1 PF00383.23 KKF94254.1 - 5.4e-06 26.2 0.0 8.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKF94254.1 - 3.3e-05 23.7 0.0 5.8e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 MafB19-like deaminase RecR PF02132.15 KKF94254.1 - 0.24 11.0 1.3 0.36 10.4 0.2 1.9 2 0 0 2 2 2 0 RecR protein Ammonium_transp PF00909.21 KKF94255.1 - 1.2e-107 360.0 33.6 1.4e-107 359.8 33.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family His_Phos_2 PF00328.22 KKF94256.1 - 8e-25 88.0 0.0 1e-24 87.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ydc2-catalyt PF09159.10 KKF94258.1 - 4.7e-30 105.3 2.4 1.3e-28 100.5 2.4 2.7 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 KKF94258.1 - 0.0033 17.6 0.2 8.6 6.5 0.0 3.5 4 0 0 4 4 4 2 Poxvirus A22 protein OrfB_IS605 PF01385.19 KKF94258.1 - 0.0063 16.7 0.0 0.035 14.3 0.0 2.1 2 0 0 2 2 2 1 Probable transposase KRTAP PF11759.8 KKF94259.1 - 2.5 8.7 41.3 19 5.9 10.9 3.4 1 1 1 2 2 2 0 Keratin-associated matrix Ras PF00071.22 KKF94260.1 - 2.8e-32 111.5 0.0 3.4e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF94260.1 - 1.1e-07 32.1 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KKF94260.1 - 0.0045 16.6 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KKF94260.1 - 0.0056 16.1 0.0 0.0068 15.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 KKF94261.1 - 9.4e-12 44.6 0.0 9e-11 41.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_H_T_join PF05521.11 KKF94261.1 - 0.32 11.5 0.0 0.32 11.5 0.0 2.6 3 1 0 3 3 3 0 Phage head-tail joining protein DUF2203 PF09969.9 KKF94262.1 - 1.5 9.5 6.4 3.4 8.4 5.4 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) MAGE PF01454.19 KKF94263.1 - 4.3e-43 147.5 0.1 6.1e-37 127.4 0.0 2.2 1 1 1 2 2 2 2 MAGE family SLS PF14611.6 KKF94264.1 - 2.4e-08 34.1 1.2 4.1e-07 30.1 1.2 2.7 1 1 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.27 KKF94265.1 - 5.4e-54 182.7 0.0 8.2e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KKF94265.1 - 6e-41 139.3 0.0 1.1e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKF94265.1 - 4.8e-15 55.7 0.7 4.8e-15 55.7 0.7 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKF94265.1 - 0.001 19.1 0.1 0.24 11.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KKF94265.1 - 0.082 12.8 0.2 0.25 11.3 0.2 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Adaptin_N PF01602.20 KKF94266.1 - 2.8e-114 382.5 1.2 3.7e-114 382.2 1.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KKF94266.1 - 3.7e-56 189.5 1.6 7.6e-56 188.5 1.6 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KKF94266.1 - 3.2e-32 111.1 0.2 1.3e-31 109.1 0.2 2.1 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform CDP-OH_P_transf PF01066.21 KKF94266.1 - 2e-16 60.5 0.1 2e-16 60.5 0.1 3.4 3 1 0 3 3 2 1 CDP-alcohol phosphatidyltransferase HEAT_2 PF13646.6 KKF94266.1 - 1.9e-15 57.0 3.7 4.2e-11 43.1 0.1 5.1 3 1 1 4 4 4 1 HEAT repeats Cnd1 PF12717.7 KKF94266.1 - 4.9e-07 29.9 13.8 0.021 14.9 0.2 5.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KKF94266.1 - 0.004 16.8 3.4 0.042 13.4 0.1 3.2 3 0 0 3 3 3 1 CLASP N terminal HEAT_PBS PF03130.16 KKF94266.1 - 0.014 16.0 0.0 19 6.3 0.0 4.3 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 KKF94266.1 - 0.23 11.6 1.2 3 8.1 0.0 3.2 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KKF94266.1 - 0.35 11.4 1.4 1.3 9.6 0.3 2.6 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 KKF94266.1 - 0.47 10.9 7.4 4.8 7.7 0.3 4.7 5 0 0 5 5 5 0 HEAT repeat DUF3267 PF11667.8 KKF94266.1 - 3 8.2 7.3 1.9 8.8 1.5 2.9 2 0 0 2 2 2 0 Putative zincin peptidase bZIP_1 PF00170.21 KKF94267.1 - 4.6e-09 36.2 15.6 4.6e-09 36.2 15.6 1.6 2 0 0 2 2 2 1 bZIP transcription factor SHE3 PF17078.5 KKF94267.1 - 0.0001 22.1 2.6 0.00015 21.6 2.6 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 PAP1 PF08601.10 KKF94267.1 - 0.0008 19.2 0.1 0.0008 19.2 0.1 2.9 1 1 2 3 3 2 1 Transcription factor PAP1 V_ATPase_I PF01496.19 KKF94267.1 - 0.0037 15.3 1.0 0.0044 15.0 1.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.17 KKF94267.1 - 0.0052 17.3 10.9 0.0086 16.6 10.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KKF94267.1 - 0.008 16.2 17.7 0.046 13.8 16.8 2.2 1 1 1 2 2 2 1 Basic region leucine zipper SlyX PF04102.12 KKF94267.1 - 0.041 14.5 1.2 0.1 13.2 1.2 1.6 1 0 0 1 1 1 0 SlyX TMCO5 PF14992.6 KKF94267.1 - 0.042 13.4 2.9 0.061 12.9 2.9 1.1 1 0 0 1 1 1 0 TMCO5 family DivIC PF04977.15 KKF94267.1 - 0.048 13.4 3.6 0.088 12.6 3.6 1.4 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 KKF94267.1 - 0.049 14.3 0.2 0.098 13.3 0.2 1.5 1 0 0 1 1 1 0 Initiation control protein YabA FdhD-NarQ PF02634.15 KKF94267.1 - 0.055 13.1 1.5 0.083 12.6 1.5 1.2 1 0 0 1 1 1 0 FdhD/NarQ family FlaC_arch PF05377.11 KKF94267.1 - 0.088 13.2 3.3 0.17 12.3 3.3 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 KKF94267.1 - 0.15 12.2 3.4 0.22 11.6 3.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GvpL_GvpF PF06386.11 KKF94267.1 - 0.17 11.8 3.9 0.29 11.0 3.9 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TSC22 PF01166.18 KKF94267.1 - 0.43 10.9 3.4 4.8 7.6 1.9 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family ABC1 PF03109.16 KKF94270.1 - 2.1e-17 63.4 0.0 4.4e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KKF94270.1 - 0.00035 20.6 0.0 0.00072 19.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Septin PF00735.18 KKF94271.1 - 1.3e-31 110.0 0.0 5.4e-11 42.3 0.0 3.1 3 0 0 3 3 3 3 Septin G-alpha PF00503.20 KKF94271.1 - 0.029 13.5 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 KKF94271.1 - 0.034 13.9 0.1 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KKF94271.1 - 0.047 14.2 1.0 0.45 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KKF94271.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 KKF94271.1 - 0.13 12.3 0.0 0.41 10.7 0.0 1.9 1 0 0 1 1 1 0 Dynamin family Myb_DNA-binding PF00249.31 KKF94272.1 - 1.7e-05 24.9 0.0 5.2e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKF94272.1 - 0.00057 20.1 0.1 0.0019 18.4 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HJURP_C PF12347.8 KKF94272.1 - 0.076 13.1 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat K_channel_TID PF07941.11 KKF94272.1 - 0.76 10.3 11.9 0.49 10.9 7.5 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain COPI_C PF06957.11 KKF94272.1 - 2.3 6.9 10.9 5.4 5.7 10.9 1.5 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DNA_pol_phi PF04931.13 KKF94272.1 - 5.1 5.1 22.4 8.7 4.3 22.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi RRM_1 PF00076.22 KKF94273.1 - 2.8e-10 39.9 0.0 7.5e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3919 PF13057.6 KKF94273.1 - 0.24 11.0 6.0 0.42 10.2 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) TFIIA PF03153.13 KKF94273.1 - 1.1 9.2 26.4 0.048 13.7 19.6 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ras PF00071.22 KKF94274.1 - 9.8e-53 178.1 0.0 1.1e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF94274.1 - 3.5e-21 75.6 0.0 5.2e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF94274.1 - 4.8e-06 26.1 0.0 6.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PCI PF01399.27 KKF94276.1 - 1.6e-12 47.9 0.0 2.2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KKF94276.1 - 0.00059 19.6 0.0 0.0026 17.5 0.0 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN7 HTH_36 PF13730.6 KKF94276.1 - 0.049 13.6 0.2 8.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain PPR_2 PF13041.6 KKF94278.1 - 3e-20 72.2 0.0 2.1e-10 40.6 0.0 6.0 4 2 2 6 6 6 4 PPR repeat family PPR_3 PF13812.6 KKF94278.1 - 6.6e-13 48.5 0.0 4e-07 30.0 0.0 3.7 3 1 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KKF94278.1 - 2.4e-11 43.1 0.1 0.00028 20.5 0.0 5.9 6 0 0 6 6 6 3 PPR repeat PPR PF01535.20 KKF94278.1 - 4.2e-09 36.0 0.0 0.12 12.6 0.0 4.9 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 KKF94278.1 - 2.1e-05 24.0 0.4 0.041 13.2 0.2 2.6 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP DUF676 PF05057.14 KKF94281.1 - 8.2e-22 77.8 0.0 6.9e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) DUF915 PF06028.11 KKF94281.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 KKF94281.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PEMT PF04191.13 KKF94282.1 - 2.3e-58 195.1 8.6 1.1e-36 125.5 1.0 2.5 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 KKF94282.1 - 0.00079 19.9 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 SKICH domain HECW_N PF16562.5 KKF94282.1 - 0.0013 18.6 0.0 0.004 17.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 TnsD PF15978.5 KKF94283.1 - 2.9 6.8 5.4 0.45 9.5 0.0 1.9 2 0 0 2 2 2 0 Tn7-like transposition protein D adh_short PF00106.25 KKF94284.1 - 6.8e-31 107.3 0.7 1.5e-16 60.4 0.0 3.1 2 1 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 KKF94284.1 - 2.5e-24 86.1 2.2 1.2e-15 57.7 0.0 3.2 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF94284.1 - 4.9e-06 26.6 1.2 4.9e-06 26.6 1.2 2.4 2 1 0 2 2 2 1 KR domain Bac_luciferase PF00296.20 KKF94287.1 - 3.1e-13 49.9 0.1 4.1e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SH3_1 PF00018.28 KKF94288.1 - 3.9e-11 42.4 0.1 6.1e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKF94288.1 - 3.3e-09 36.5 0.1 5e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKF94288.1 - 3.8e-07 29.7 0.0 6.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 KKF94288.1 - 3.2 7.7 13.4 7 6.6 7.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) FAP PF07174.11 KKF94288.1 - 7.2 6.0 28.4 1.2 8.6 15.9 2.1 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) G_glu_transpept PF01019.21 KKF94290.1 - 5.7e-163 543.3 0.0 6.8e-163 543.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Binary_toxB_3 PF17476.2 KKF94290.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 3 PAP1 PF08601.10 KKF94290.1 - 1.3 8.6 6.6 2.1 8.0 6.6 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Adenylsucc_synt PF00709.21 KKF94291.1 - 2.8e-163 543.7 0.0 3.2e-163 543.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase FAD_binding_4 PF01565.23 KKF94292.1 - 9.4e-27 93.5 1.3 9.4e-27 93.5 1.3 2.1 3 0 0 3 3 3 1 FAD binding domain SUR7 PF06687.12 KKF94293.1 - 2.3e-32 112.4 9.5 2.7e-32 112.2 9.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF805 PF05656.14 KKF94293.1 - 0.00039 20.8 3.0 0.00039 20.8 3.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF805) Clc-like PF07062.12 KKF94293.1 - 0.0041 16.6 2.2 0.0041 16.6 2.2 1.5 2 0 0 2 2 2 1 Clc-like Claudin_2 PF13903.6 KKF94293.1 - 0.1 12.4 14.9 0.013 15.3 8.9 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DEFB136 PF17333.2 KKF94293.1 - 2.6 8.0 5.5 0.99 9.4 2.3 2.0 2 0 0 2 2 2 0 Beta defensin 136 RNase_H PF00075.24 KKF94294.1 - 2.3e-12 47.3 0.0 1.3e-06 28.7 0.0 2.6 2 0 0 2 2 2 2 RNase H Exo_endo_phos_2 PF14529.6 KKF94294.1 - 7.9e-10 38.6 0.1 3.6e-09 36.5 0.1 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KKF94294.1 - 2.7e-07 30.4 0.0 7.8e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHC2_SAM_assoc PF16616.5 KKF94294.1 - 0.032 15.1 5.8 0.031 15.1 3.2 2.3 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 p450 PF00067.22 KKF94295.1 - 1.9e-53 181.9 0.0 3.2e-53 181.1 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 PLDc PF00614.22 KKF94295.1 - 0.055 13.7 0.0 3.8 7.9 0.1 2.5 2 0 0 2 2 2 0 Phospholipase D Active site motif Stirrup PF09061.6 KKF94295.1 - 0.057 13.6 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 Stirrup Cys_rich_FGFR PF00839.17 KKF94295.1 - 0.059 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Cysteine rich repeat LSM PF01423.22 KKF94296.1 - 9.1e-16 57.3 0.2 1.3e-15 56.8 0.2 1.3 1 0 0 1 1 1 1 LSM domain GCD14 PF08704.10 KKF94297.1 - 5.1e-65 219.6 0.2 3.8e-43 147.9 0.0 2.7 3 0 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit UQ_con PF00179.26 KKF94298.1 - 6.6e-52 174.9 0.0 7.5e-52 174.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKF94298.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B TPR_2 PF07719.17 KKF94299.1 - 0.0001 22.2 0.1 4.1 7.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKF94299.1 - 0.0006 19.5 0.0 2.6 8.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKF94299.1 - 0.018 15.3 0.0 2.7 8.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 KKF94299.1 - 0.056 13.6 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain DUF1996 PF09362.10 KKF94300.1 - 3.1e-83 279.4 0.1 3.9e-83 279.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Voldacs PF03517.13 KKF94301.1 - 3e-11 43.6 0.5 2.9e-09 37.2 0.6 2.3 2 0 0 2 2 2 2 Regulator of volume decrease after cellular swelling Adap_comp_sub PF00928.21 KKF94303.1 - 2.3e-90 302.6 0.0 3.1e-90 302.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KKF94303.1 - 2.9e-08 33.8 0.3 4.8e-08 33.0 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KKF94303.1 - 0.1 12.1 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain SET PF00856.28 KKF94304.1 - 2.4e-18 67.1 0.0 3.8e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KKF94304.1 - 7.4e-09 36.4 0.3 1.7e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding AHD PF17793.1 KKF94305.1 - 0.02 14.7 0.1 0.074 12.9 0.0 1.9 2 0 0 2 2 2 0 ANC1 homology domain (AHD) DUF1308 PF07000.11 KKF94306.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1308) zf-Tim10_DDP PF02953.15 KKF94307.1 - 2.4e-14 52.7 4.1 2.4e-14 52.7 4.1 1.8 2 0 0 2 2 2 1 Tim10/DDP family zinc finger Nup188_C PF18378.1 KKF94308.1 - 2.3e-142 474.2 4.2 3.5e-142 473.6 4.2 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KKF94308.1 - 2.8e-39 134.8 0.0 3.1e-29 101.6 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 RhoGAP PF00620.27 KKF94309.1 - 1.3e-38 132.2 0.0 1.9e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Haemagg_act PF05860.13 KKF94309.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 haemagglutination activity domain Glyco_hydro_16 PF00722.21 KKF94311.1 - 1.5e-06 27.8 1.7 4.3e-06 26.3 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 tRNA_int_endo PF01974.17 KKF94312.1 - 4.2e-16 58.8 0.0 9.6e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KKF94312.1 - 7.3e-05 22.4 0.1 0.002 17.8 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain TauD PF02668.16 KKF94313.1 - 2.4e-36 125.9 0.4 3.8e-36 125.3 0.4 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KKF94313.1 - 3.9e-07 30.6 0.0 8.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) SGS PF05002.15 KKF94314.1 - 3.3e-29 100.8 2.7 3.3e-29 100.8 2.7 1.9 2 0 0 2 2 2 1 SGS domain CS PF04969.16 KKF94314.1 - 3.6e-06 27.9 0.0 6.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 KKF94314.1 - 2.2e-05 24.2 3.8 0.13 12.5 0.9 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKF94314.1 - 0.016 15.9 11.3 0.27 11.9 8.9 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKF94314.1 - 0.084 13.4 4.9 0.18 12.3 2.5 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKF94314.1 - 0.38 10.6 4.0 0.25 11.2 0.4 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKF94314.1 - 4.1 7.8 7.3 4.3 7.7 5.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Ala_racemase_N PF01168.20 KKF94315.1 - 1.2e-22 80.6 0.0 1.5e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 KKF94316.1 - 1e-123 413.7 6.7 1.2e-123 413.5 6.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KKF94316.1 - 1.4e-44 150.9 0.0 3.4e-44 149.6 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KKF94316.1 - 2.8e-15 56.6 0.0 6.2e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 KKF94316.1 - 0.12 12.5 0.1 0.49 10.6 0.1 2.0 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Methyltransf_23 PF13489.6 KKF94317.1 - 9.7e-07 28.8 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF94317.1 - 5e-06 27.1 0.0 1e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF94317.1 - 1e-05 26.2 0.0 1.9e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF94317.1 - 0.00015 22.4 0.0 0.00054 20.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF94317.1 - 0.12 12.2 0.0 0.44 10.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain P16-Arc PF04699.14 KKF94318.1 - 3.5e-31 108.7 0.0 4e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Ank_2 PF12796.7 KKF94319.1 - 9.2e-15 55.0 2.2 1.6e-11 44.6 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKF94319.1 - 9.3e-14 51.6 1.0 3.6e-06 27.4 0.1 2.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKF94319.1 - 4.7e-13 49.1 1.5 1.7e-08 34.6 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKF94319.1 - 2.1e-09 36.8 0.1 0.0019 18.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KKF94319.1 - 5.8e-08 32.8 0.2 0.002 18.5 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat SQHop_cyclase_C PF13243.6 KKF94320.1 - 1.8e-45 155.4 3.7 1.4e-37 129.5 0.6 3.2 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KKF94320.1 - 1.4e-40 139.2 2.8 1.5e-33 116.2 0.1 3.2 3 0 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KKF94320.1 - 3.7e-28 97.0 7.9 6.4e-10 38.6 0.1 5.6 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KKF94320.1 - 4.1e-05 22.7 1.7 0.0021 17.1 0.5 3.4 2 1 1 3 3 3 1 A-macroglobulin TED domain Pec_lyase PF09492.10 KKF94320.1 - 0.0065 15.8 1.4 3 7.1 0.0 4.1 3 1 2 5 5 5 1 Pectic acid lyase SET PF00856.28 KKF94322.1 - 0.036 14.5 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 SET domain DUF2282 PF10048.9 KKF94323.1 - 0.19 11.7 0.2 0.43 10.6 0.2 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) CtaG_Cox11 PF04442.14 KKF94324.1 - 2.4e-58 196.5 0.0 5.1e-58 195.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Ribosomal_L26 PF16906.5 KKF94324.1 - 4.9e-38 129.4 1.5 1.1e-37 128.3 1.5 1.6 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KKF94324.1 - 6.8e-07 29.0 1.4 1.8e-06 27.7 1.4 1.7 1 0 0 1 1 1 1 KOW motif V-SNARE PF05008.15 KKF94325.1 - 1.1e-20 73.8 5.7 1.1e-20 73.8 5.7 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KKF94325.1 - 2.2e-18 66.3 2.6 2.2e-18 66.3 2.6 2.5 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KKF94325.1 - 0.00013 21.9 0.5 0.00037 20.3 0.5 1.8 1 0 0 1 1 1 1 Sec20 FAM76 PF16046.5 KKF94325.1 - 0.028 13.8 0.4 0.028 13.8 0.4 1.4 2 0 0 2 2 2 0 FAM76 protein Fusion_gly PF00523.18 KKF94325.1 - 0.045 12.0 1.2 0.047 11.9 0.2 1.6 2 0 0 2 2 2 0 Fusion glycoprotein F0 Synaptobrevin PF00957.21 KKF94325.1 - 0.15 11.9 1.5 0.25 11.2 0.1 2.1 2 0 0 2 2 2 0 Synaptobrevin Use1 PF09753.9 KKF94325.1 - 0.39 10.4 10.3 9.4 5.9 10.3 2.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 Atg14 PF10186.9 KKF94325.1 - 0.9 8.6 7.7 1.3 8.1 7.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliJ PF02050.16 KKF94325.1 - 5.9 7.1 13.5 1.1 9.4 2.3 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein NUC173 PF08161.12 KKF94326.1 - 1.7e-76 256.4 0.2 1.4e-73 247.0 0.0 3.0 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.22 KKF94326.1 - 0.01 16.0 0.6 5.5 7.5 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat TetR_C_15 PF17918.1 KKF94326.1 - 7 7.5 6.5 70 4.2 0.0 4.1 4 1 1 5 5 5 0 Tetracyclin repressor-like, C-terminal domain C2 PF00168.30 KKF94327.1 - 2.4e-23 82.4 0.0 1.3e-12 47.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain PET117 PF15786.5 KKF94327.1 - 9.6 6.6 7.2 29 5.0 4.5 2.5 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial IMS PF00817.20 KKF94329.1 - 4.8e-39 133.8 0.0 1.4e-38 132.3 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KKF94329.1 - 1.5e-11 45.0 0.1 2.7e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf-C2H2_4 PF13894.6 KKF94329.1 - 0.077 13.9 0.2 0.23 12.4 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger DUF974 PF06159.13 KKF94330.1 - 1.7e-57 195.1 0.0 2.2e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) RTA1 PF04479.13 KKF94332.1 - 5.3e-66 222.2 10.0 5.3e-66 222.2 10.0 1.3 2 0 0 2 2 2 1 RTA1 like protein VPS9 PF02204.18 KKF94333.1 - 3.2e-25 88.3 0.0 5.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Adeno_PV PF03910.13 KKF94333.1 - 2.8 6.6 5.6 5.1 5.7 5.6 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV Pkinase PF00069.25 KKF94335.1 - 4.4e-57 193.4 0.0 9e-57 192.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF94335.1 - 2.4e-29 102.4 0.0 5.2e-29 101.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF94335.1 - 0.0036 16.7 0.0 0.008 15.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KKF94335.1 - 0.03 14.2 2.1 0.031 14.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Borrelia_P83 PF05262.11 KKF94335.1 - 1.5 7.3 6.8 2.3 6.6 6.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Methyltransf_28 PF02636.17 KKF94336.1 - 5.7e-70 235.9 0.0 6.9e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KKF94336.1 - 0.094 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Lung_7-TM_R PF06814.13 KKF94337.1 - 2.2e-66 224.1 14.3 2.7e-66 223.8 14.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4131 PF13567.6 KKF94337.1 - 3.2 7.4 9.0 0.59 9.8 0.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Pro_isomerase PF00160.21 KKF94338.1 - 1.6e-45 155.2 0.0 2.9e-45 154.4 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KKF94338.1 - 2.5e-06 27.6 0.1 2.2e-05 24.5 0.0 2.6 3 0 0 3 3 3 1 U-box domain zf-NOSIP PF15906.5 KKF94338.1 - 0.0012 18.9 0.0 0.0033 17.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Glyco_hydro_64 PF16483.5 KKF94340.1 - 2e-82 277.4 0.1 1.5e-80 271.3 0.1 2.0 1 1 0 1 1 1 1 Beta-1,3-glucanase Fungal_trans PF04082.18 KKF94341.1 - 2.4e-16 59.6 3.9 3.7e-16 58.9 3.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KKF94341.1 - 3.6e-08 33.5 11.8 1.1e-05 25.6 5.8 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KKF94341.1 - 0.00083 19.7 14.6 0.04 14.4 5.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KKF94341.1 - 0.007 17.0 0.7 1.3 9.7 0.1 2.7 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 KKF94341.1 - 0.23 12.4 19.5 0.27 12.2 4.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKF94341.1 - 0.51 10.7 3.7 1.4 9.3 3.7 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KKF94341.1 - 1.7 8.8 4.1 4.1 7.6 4.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Cullin PF00888.22 KKF94342.1 - 4.7e-188 626.7 6.9 6.7e-188 626.2 6.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KKF94342.1 - 5e-26 90.5 5.2 5e-26 90.5 5.2 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain YtzH PF14165.6 KKF94342.1 - 0.03 14.7 0.1 0.16 12.4 0.1 2.3 1 0 0 1 1 1 0 YtzH-like protein WAC_Acf1_DNA_bd PF10537.9 KKF94342.1 - 0.041 14.4 1.1 0.18 12.3 0.5 2.4 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF1803 PF08820.10 KKF94342.1 - 1.3 9.1 5.0 10 6.2 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1803) DUF1129 PF06570.11 KKF94343.1 - 0.076 12.5 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PRCC PF10253.9 KKF94343.1 - 0.65 10.7 3.4 0.45 11.3 1.6 1.6 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Mit_KHE1 PF10173.9 KKF94344.1 - 3.1e-60 203.5 0.2 3.1e-60 203.5 0.2 2.6 2 1 1 3 3 3 1 Mitochondrial K+-H+ exchange-related Atg14 PF10186.9 KKF94346.1 - 0.12 11.5 1.5 0.17 10.9 1.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rootletin PF15035.6 KKF94346.1 - 0.45 10.5 8.3 2.3 8.2 8.3 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Svf1_C PF17187.4 KKF94347.1 - 8.9e-57 191.5 0.2 1.4e-56 190.9 0.2 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KKF94347.1 - 2.3e-54 183.8 0.0 3.4e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Nop25 PF09805.9 KKF94348.1 - 0.045 14.2 0.7 0.085 13.3 0.7 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) HD_3 PF13023.6 KKF94349.1 - 6.2e-44 149.8 0.3 7.8e-44 149.5 0.3 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KKF94349.1 - 8.6e-11 41.9 0.2 1.2e-10 41.5 0.2 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KKF94349.1 - 0.00061 20.0 0.1 0.0011 19.1 0.1 1.6 1 1 0 1 1 1 1 HD domain DUF1071 PF06378.11 KKF94349.1 - 0.034 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Cupin_8 PF13621.6 KKF94350.1 - 1.4e-30 106.9 0.0 2.2e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KKF94350.1 - 9.4e-10 38.5 0.0 1.6e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_2 PF07883.11 KKF94350.1 - 0.00062 19.4 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 KKF94350.1 - 0.00068 20.0 0.0 0.011 16.1 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase CENP-Q PF13094.6 KKF94351.1 - 7.5e-05 23.0 7.4 0.00053 20.2 2.1 2.5 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.6 KKF94351.1 - 0.022 14.1 3.9 0.043 13.2 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 KKF94351.1 - 0.022 15.3 4.8 1.9 9.1 0.1 3.4 3 0 0 3 3 3 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 KKF94351.1 - 0.024 15.0 3.6 0.56 10.6 1.6 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 KKF94351.1 - 0.034 14.4 7.5 2.7 8.2 0.1 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Dor1 PF04124.12 KKF94351.1 - 0.087 11.5 1.1 0.17 10.5 1.0 1.4 1 1 0 1 1 1 0 Dor1-like family DivIVA PF05103.13 KKF94351.1 - 0.093 12.8 7.5 1.6 8.9 3.8 2.4 2 0 0 2 2 2 0 DivIVA protein RmuC PF02646.16 KKF94351.1 - 0.13 11.4 4.7 0.53 9.4 0.7 2.1 2 0 0 2 2 2 0 RmuC family ZapB PF06005.12 KKF94351.1 - 0.14 12.6 13.3 0.66 10.5 5.6 2.5 2 0 0 2 2 2 0 Cell division protein ZapB HMMR_C PF15908.5 KKF94351.1 - 0.25 11.6 5.8 3.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Ax_dynein_light PF10211.9 KKF94351.1 - 0.46 10.4 14.6 2.3 8.1 7.6 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain GAS PF13851.6 KKF94351.1 - 0.68 9.2 15.4 0.87 8.9 9.2 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spectrin PF00435.21 KKF94351.1 - 0.7 10.4 8.2 4.7 7.8 3.8 2.3 2 0 0 2 2 2 0 Spectrin repeat Prefoldin_2 PF01920.20 KKF94351.1 - 0.78 9.7 11.1 6 6.9 6.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit Sec34 PF04136.15 KKF94351.1 - 0.78 9.6 4.3 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Sec34-like family CtIP_N PF10482.9 KKF94351.1 - 0.78 9.8 7.5 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Leu_zip PF15294.6 KKF94351.1 - 0.96 8.9 7.8 0.91 9.0 4.1 2.1 2 0 0 2 2 2 0 Leucine zipper Phage_GP20 PF06810.11 KKF94351.1 - 1 9.2 11.4 0.92 9.3 6.7 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 UPF0242 PF06785.11 KKF94351.1 - 3.5 7.7 10.4 6.6 6.8 7.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 KKF94351.1 - 3.7 7.6 14.1 8.8 6.3 7.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 KKF94351.1 - 3.8 7.7 13.8 15 5.8 0.2 3.3 2 1 0 2 2 2 0 bZIP transcription factor XhlA PF10779.9 KKF94351.1 - 3.9 7.7 6.8 3.8 7.8 3.4 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Spc24 PF08286.11 KKF94351.1 - 4.6 7.5 8.0 3.5 7.9 2.8 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.8 KKF94351.1 - 4.9 7.2 15.4 14 5.8 8.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 KKF94351.1 - 6.1 7.4 18.0 0.96 10.0 10.5 2.3 1 1 0 2 2 2 0 Apg6 coiled-coil region VASt PF16016.5 KKF94352.1 - 8.8e-27 94.4 0.5 6.3e-22 78.6 0.0 2.4 1 1 1 2 2 2 2 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KKF94352.1 - 1.2e-11 44.5 0.2 5e-10 39.3 0.1 2.3 1 1 1 2 2 2 2 GRAM domain LUC7 PF03194.15 KKF94352.1 - 0.026 14.2 0.5 0.046 13.4 0.5 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Abhydrolase_1 PF00561.20 KKF94353.1 - 6.5e-47 160.3 0.0 1.4e-45 155.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKF94353.1 - 0.00027 21.6 0.4 0.0054 17.4 0.4 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family THOC2_N PF16134.5 KKF94354.1 - 5.4e-140 468.0 0.0 6.4e-117 391.8 0.0 2.3 1 1 1 2 2 2 2 THO complex subunit 2 N-terminus Tho2 PF11262.8 KKF94354.1 - 2.6e-94 315.8 0.5 4.8e-94 314.9 0.5 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KKF94354.1 - 6.3e-29 99.9 0.6 1.9e-28 98.4 0.2 2.1 2 0 0 2 2 2 1 Transcription- and export-related complex subunit PP2C PF00481.21 KKF94356.1 - 2.1e-65 220.9 0.6 7.4e-51 173.3 0.2 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C Lipoprotein_2 PF00921.17 KKF94356.1 - 0.045 13.3 3.7 0.073 12.6 3.7 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein A_deaminase PF00962.22 KKF94358.1 - 1e-30 107.2 0.0 3.3e-16 59.5 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase Amidohydro_3 PF07969.11 KKF94358.1 - 0.0039 16.7 0.2 0.044 13.2 0.2 2.2 1 1 0 1 1 1 1 Amidohydrolase family TatD_DNase PF01026.21 KKF94358.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase Tom22 PF04281.13 KKF94359.1 - 2.2e-40 137.7 0.4 2.6e-40 137.4 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Asp PF00026.23 KKF94361.1 - 1.3e-58 198.9 0.1 1.7e-58 198.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKF94361.1 - 1e-10 42.2 2.6 1e-10 42.2 2.6 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKF94361.1 - 0.00044 20.8 0.0 0.36 11.5 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KKF94361.1 - 0.033 14.7 0.0 0.34 11.5 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Glyco_transf_8 PF01501.20 KKF94362.1 - 5.2e-05 22.9 0.1 0.00012 21.7 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 peroxidase PF00141.23 KKF94363.1 - 1.5e-26 93.5 0.0 2.4e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase NUDIX PF00293.28 KKF94364.1 - 1.2e-17 64.2 0.2 4.8e-17 62.2 0.2 1.8 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KKF94364.1 - 0.034 14.1 0.1 0.7 9.9 0.0 2.4 1 1 1 2 2 2 0 NUDIX domain DUF2235 PF09994.9 KKF94365.1 - 1.7e-101 339.4 0.4 2.2e-101 339.0 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Arrestin_C PF02752.22 KKF94366.1 - 2.1e-11 44.4 0.0 3.6e-10 40.4 0.0 2.9 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KKF94366.1 - 0.0017 18.4 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DUF4402 PF14352.6 KKF94366.1 - 2.3 8.9 3.6 9.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4402) Glyco_hydro_10 PF00331.20 KKF94367.1 - 5.7e-99 331.2 0.3 6.9e-99 331.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KKF94367.1 - 6.4e-12 45.2 9.3 6.4e-12 45.2 9.3 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Pkinase_fungal PF17667.1 KKF94368.1 - 2.8e-58 197.6 0.1 3.3e-58 197.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KKF94368.1 - 2.6e-10 40.1 0.0 3.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF94368.1 - 0.0053 16.1 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKF94368.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KKF94368.1 - 0.093 12.1 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.29 KKF94369.1 - 7.8e-42 142.8 0.0 1.7e-41 141.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KKF94369.1 - 1.9e-27 95.0 0.3 1.3e-26 92.3 0.1 2.5 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KKF94369.1 - 6.6e-23 80.6 1.6 6.6e-23 80.6 1.6 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KKF94369.1 - 1.6e-07 31.0 0.0 4.9e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KKF94369.1 - 3.3e-07 30.2 0.0 5.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKF94369.1 - 7.1e-06 26.5 0.5 0.0024 18.3 0.0 3.2 2 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KKF94369.1 - 1.9e-05 24.5 0.1 4.8e-05 23.2 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KKF94369.1 - 2.8e-05 24.4 0.4 0.013 15.9 0.0 3.4 3 0 0 3 3 3 1 RNA helicase TIP49 PF06068.13 KKF94369.1 - 3.8e-05 23.1 0.8 9.4e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 KKF94369.1 - 6.2e-05 23.0 0.0 0.00021 21.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.13 KKF94369.1 - 9.6e-05 21.7 0.0 0.00021 20.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KKF94369.1 - 0.0001 22.3 0.4 0.00055 19.9 0.0 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKF94369.1 - 0.00022 21.5 1.6 0.02 15.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KKF94369.1 - 0.00035 20.7 0.0 0.0071 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKF94369.1 - 0.0016 19.0 1.3 0.003 18.1 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KKF94369.1 - 0.0031 17.3 1.3 0.0052 16.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KKF94369.1 - 0.006 17.0 1.5 0.064 13.7 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_2 PF07724.14 KKF94369.1 - 0.0071 16.5 0.0 0.031 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KKF94369.1 - 0.026 13.9 0.0 0.082 12.3 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KKF94369.1 - 0.036 13.6 1.7 0.13 11.7 0.0 2.8 3 1 0 3 3 3 0 P-loop containing dynein motor region PhoH PF02562.16 KKF94369.1 - 0.045 13.2 0.8 0.15 11.5 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Cytidylate_kin PF02224.18 KKF94369.1 - 0.09 12.5 0.1 0.51 10.0 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase Torsin PF06309.11 KKF94369.1 - 0.093 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Torsin Parvo_NS1 PF01057.17 KKF94369.1 - 0.099 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KKF94369.1 - 0.11 12.3 1.1 0.67 9.8 0.0 2.6 2 1 1 3 3 3 0 NACHT domain ABC_tran PF00005.27 KKF94369.1 - 0.13 12.8 1.1 2.5 8.6 0.0 2.8 2 1 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 KKF94369.1 - 0.14 11.8 0.5 0.56 9.9 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain ATPase PF06745.13 KKF94369.1 - 0.17 11.2 0.0 5.6 6.3 0.0 2.7 2 1 1 3 3 2 0 KaiC AAA_25 PF13481.6 KKF94369.1 - 0.31 10.6 5.5 0.33 10.5 0.1 3.1 3 1 0 4 4 4 0 AAA domain AAA_29 PF13555.6 KKF94369.1 - 4.5 7.1 7.5 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Prefoldin_2 PF01920.20 KKF94370.1 - 6.9e-17 61.3 12.0 6.9e-17 61.3 12.0 1.7 2 0 0 2 2 2 1 Prefoldin subunit JAB PF01398.21 KKF94370.1 - 1.1e-13 51.2 0.2 6.7e-13 48.7 0.0 2.3 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KKF94370.1 - 8.3e-05 22.8 0.3 8.3e-05 22.8 0.3 2.2 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 KKF94370.1 - 0.00043 20.0 0.1 0.0015 18.3 0.1 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Fez1 PF06818.15 KKF94370.1 - 0.014 15.9 0.2 0.014 15.9 0.2 2.8 3 0 0 3 3 3 0 Fez1 DivIC PF04977.15 KKF94370.1 - 0.085 12.6 13.5 0.91 9.3 4.6 3.2 2 1 1 3 3 3 0 Septum formation initiator End3 PF12761.7 KKF94370.1 - 0.11 12.7 7.9 0.18 11.9 7.9 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 BRE1 PF08647.11 KKF94370.1 - 0.57 10.3 12.6 0.98 9.5 0.8 2.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Uso1_p115_C PF04871.13 KKF94370.1 - 0.81 10.1 10.2 0.38 11.1 4.6 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MIP-T3_C PF17749.1 KKF94370.1 - 1.6 8.7 10.2 0.11 12.5 2.2 2.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region GAS PF13851.6 KKF94370.1 - 2.3 7.5 11.9 1.6 8.0 4.1 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.12 KKF94370.1 - 4 7.8 7.7 1.4 9.3 0.4 2.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) YabA PF06156.13 KKF94370.1 - 6.6 7.4 10.4 17 6.1 0.2 3.3 3 0 0 3 3 3 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 KKF94370.1 - 7.4 6.9 17.1 0.37 11.1 1.0 3.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 KKF94370.1 - 8.4 6.5 11.0 12 6.1 4.0 2.5 2 0 0 2 2 2 0 Tropomyosin like NPV_P10 PF05531.12 KKF94370.1 - 9.1 6.8 11.3 9.7 6.7 3.3 2.7 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF1772 PF08592.11 KKF94371.1 - 9.7e-32 110.2 0.6 1.4e-31 109.6 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Fe-ADH PF00465.19 KKF94371.1 - 0.053 12.3 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Fungal_trans PF04082.18 KKF94372.1 - 6.2e-05 22.2 0.4 0.0001 21.4 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mrx7 PF10906.8 KKF94374.1 - 0.00077 19.7 0.0 0.0016 18.6 0.0 1.6 1 1 0 1 1 1 1 MIOREX complex component 7 2OG-FeII_Oxy PF03171.20 KKF94376.1 - 3.4e-19 69.2 0.0 7.5e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KKF94376.1 - 1.8e-15 57.7 0.0 2.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal U-box PF04564.15 KKF94376.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 U-box domain E1-E2_ATPase PF00122.20 KKF94377.1 - 5.5e-34 117.3 16.0 8.3e-29 100.4 0.2 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKF94377.1 - 4.5e-22 78.6 7.8 4.5e-22 78.6 7.8 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KKF94377.1 - 1.3e-17 64.8 0.0 4.1e-16 59.9 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKF94377.1 - 1.6e-17 63.3 0.0 3.4e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KKF94377.1 - 3.8e-12 45.7 0.0 7.7e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKF94377.1 - 0.00085 19.1 0.6 0.0091 15.8 0.5 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SieB PF14163.6 KKF94377.1 - 0.071 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B Cerato-platanin PF07249.12 KKF94378.1 - 1e-05 25.7 0.1 2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Cerato-platanin EBP50_C PF09007.11 KKF94378.1 - 0.058 14.4 0.5 0.097 13.7 0.5 1.3 1 0 0 1 1 1 0 EBP50, C-terminal Pribosyltran_N PF13793.6 KKF94379.1 - 3e-33 114.2 0.0 1.3e-32 112.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KKF94379.1 - 2e-29 103.0 2.7 7.4e-24 84.8 1.5 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KKF94379.1 - 4.3e-12 45.8 0.4 8e-12 45.0 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain LrgB PF04172.16 KKF94380.1 - 3.7e-55 186.7 15.2 3.7e-55 186.7 15.2 2.2 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 KKF94380.1 - 4.2e-07 29.8 6.0 4.2e-07 29.8 6.0 3.9 5 1 0 5 5 5 1 LrgA family adh_short PF00106.25 KKF94381.1 - 5.3e-31 107.6 0.0 6.5e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF94381.1 - 2.9e-23 82.7 0.0 3.7e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF94381.1 - 0.0015 18.4 0.1 0.0053 16.7 0.1 2.0 1 1 0 1 1 1 1 KR domain 3HBOH PF10605.9 KKF94382.1 - 0.11 10.7 1.1 0.13 10.5 1.1 1.0 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) E1-E2_ATPase PF00122.20 KKF94383.1 - 1.8e-39 135.2 16.2 3.2e-35 121.3 7.1 4.2 3 1 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKF94383.1 - 1.4e-27 96.6 0.7 1.4e-27 96.6 0.7 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KKF94383.1 - 1.3e-17 64.8 0.0 1e-16 61.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKF94383.1 - 1.2e-15 57.4 0.0 2.9e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KKF94383.1 - 3.6e-14 52.2 0.0 8e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKF94383.1 - 1.6e-05 24.8 0.9 0.00012 21.9 0.9 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1385 PF07136.11 KKF94383.1 - 0.081 12.2 1.1 0.59 9.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) CCDC14 PF15254.6 KKF94383.1 - 0.21 10.2 1.8 0.33 9.6 1.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Polyketide_cyc2 PF10604.9 KKF94384.1 - 0.2 11.9 5.2 0.53 10.5 5.2 1.7 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF3313 PF11769.8 KKF94385.1 - 0.025 14.4 0.4 0.028 14.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Pox_A12 PF04651.13 KKF94385.1 - 0.096 12.7 1.0 0.11 12.5 1.0 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein TFIIA PF03153.13 KKF94386.1 - 0.002 18.2 29.9 0.002 18.2 29.9 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SOBP PF15279.6 KKF94386.1 - 8.6 6.9 28.2 1.4 9.4 22.4 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein CAF1A PF12253.8 KKF94387.1 - 5.9e-18 64.8 2.4 5.9e-18 64.8 2.4 3.0 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A FYDLN_acid PF09538.10 KKF94387.1 - 0.041 14.6 1.7 0.041 14.6 1.7 4.0 3 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DDHD PF02862.17 KKF94387.1 - 4.3 7.4 8.2 10 6.2 8.2 1.7 1 0 0 1 1 1 0 DDHD domain DUF4551 PF15087.6 KKF94387.1 - 6.2 5.5 14.1 10 4.8 14.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CRAL_TRIO PF00650.20 KKF94388.1 - 4.9e-38 130.4 0.0 6.8e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKF94388.1 - 2.8e-12 46.6 0.7 2.8e-12 46.6 0.7 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KKF94388.1 - 0.03 14.5 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain HrpB_C PF08482.10 KKF94388.1 - 0.038 14.4 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal HNH_5 PF14279.6 KKF94388.1 - 0.098 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease TRAPP PF04051.16 KKF94389.1 - 2.3e-40 137.7 0.0 2.8e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Apc13p PF05839.11 KKF94390.1 - 4.9e-31 106.8 0.1 5.5e-31 106.6 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein RasGAP PF00616.19 KKF94392.1 - 2.6e-28 99.2 7.1 1.4e-19 70.6 0.0 3.7 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KKF94392.1 - 1.4e-05 25.3 0.0 2.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Phage_Integr_2 PF13009.6 KKF94392.1 - 0.17 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Putative phage integrase Pro_isomerase PF00160.21 KKF94393.1 - 9e-45 152.8 0.1 1.3e-44 152.3 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KKF94393.1 - 4.7e-05 23.2 6.9 0.0035 17.3 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKF94393.1 - 8.6e-05 22.2 1.4 0.028 14.3 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKF94393.1 - 0.0075 16.5 1.7 0.014 15.7 1.7 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKF94393.1 - 0.019 15.1 0.1 0.019 15.1 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KKF94393.1 - 0.5 10.9 2.3 33 5.1 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.16 KKF94394.1 - 3e-47 160.8 0.0 3.3e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 KKF94395.1 - 6.4e-90 300.6 21.0 1.1e-89 299.8 21.0 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KKF94395.1 - 3.3e-36 124.3 8.8 8e-36 123.0 8.8 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 KKF94395.1 - 0.002 17.9 1.5 0.0052 16.6 1.5 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 KKF94395.1 - 0.0022 18.3 2.0 0.012 16.0 2.0 2.3 1 0 0 1 1 1 1 Syntaxin-like protein Cep57_MT_bd PF06657.13 KKF94395.1 - 0.44 11.0 7.9 0.54 10.8 1.4 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 STIMATE PF12400.8 KKF94397.1 - 1.2e-42 145.4 3.8 1.2e-42 145.4 3.8 1.7 2 0 0 2 2 2 1 STIMATE family DUF4271 PF14093.6 KKF94397.1 - 0.05 13.5 2.2 0.059 13.3 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) Sod_Fe_C PF02777.18 KKF94398.1 - 3.9e-17 62.3 0.2 4.8e-15 55.6 0.2 2.3 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain SAM_2 PF07647.17 KKF94399.1 - 0.0021 18.1 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KKF94399.1 - 0.032 14.7 0.0 0.22 12.0 0.0 2.1 2 0 0 2 2 2 0 PH domain SAM_1 PF00536.30 KKF94399.1 - 0.042 14.3 0.0 0.095 13.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Fungal_trans_2 PF11951.8 KKF94400.1 - 3.2e-74 250.0 0.4 4.3e-74 249.6 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF94400.1 - 6.9e-05 22.9 2.0 0.00015 21.8 2.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4763 PF15960.5 KKF94400.1 - 0.076 12.3 0.5 0.13 11.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) MCPVI PF02993.14 KKF94400.1 - 0.48 10.2 5.9 1.2 8.9 5.9 1.6 1 0 0 1 1 1 0 Minor capsid protein VI DUF916 PF06030.12 KKF94402.1 - 0.031 14.4 0.1 0.056 13.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) DUF5401 PF17380.2 KKF94403.1 - 0.078 11.0 49.0 0.11 10.6 49.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Cytochrom_CIII PF02085.16 KKF94406.1 - 0.0042 17.4 4.4 0.0042 17.4 4.4 2.1 2 0 0 2 2 2 1 Class III cytochrome C family zf-CHCC PF10276.9 KKF94406.1 - 0.0062 16.6 2.3 2.5 8.2 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger domain PyrI_C PF02748.15 KKF94406.1 - 0.0063 16.4 2.6 0.65 9.9 1.0 2.4 2 0 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 PF00096.26 KKF94406.1 - 0.016 15.7 2.8 0.016 15.7 2.8 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type She9_MDM33 PF05546.11 KKF94406.1 - 0.03 14.1 2.1 0.041 13.7 1.9 1.4 1 1 0 1 1 1 0 She9 / Mdm33 family PSCyt3 PF07627.11 KKF94406.1 - 0.63 10.3 4.5 0.27 11.6 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) HNH_5 PF14279.6 KKF94406.1 - 2.2 8.2 8.6 13 5.7 1.1 3.4 3 0 0 3 3 3 0 HNH endonuclease zf-BED PF02892.15 KKF94406.1 - 2.3 8.3 21.5 0.94 9.6 1.4 4.2 4 0 0 4 4 4 0 BED zinc finger DSPc PF00782.20 KKF94407.1 - 1.5e-13 50.7 0.1 1.2e-07 31.6 0.7 3.2 2 1 1 3 3 3 3 Dual specificity phosphatase, catalytic domain Vfa1 PF08432.10 KKF94408.1 - 2.3e-34 119.3 22.4 6.8e-34 117.8 22.4 1.7 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Death_2 PF14786.6 KKF94408.1 - 0.0029 17.5 0.6 0.063 13.2 0.0 2.1 1 1 1 2 2 2 1 Tube Death domain Asp-B-Hydro_N PF05279.11 KKF94408.1 - 0.15 12.1 19.8 0.19 11.8 19.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AAA_15 PF13175.6 KKF94408.1 - 0.15 11.7 10.4 0.18 11.5 10.4 1.0 1 0 0 1 1 1 0 AAA ATPase domain DUF2992 PF11208.8 KKF94408.1 - 0.19 12.0 17.6 0.028 14.6 13.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2992) DUF4228 PF14009.6 KKF94408.1 - 0.37 11.1 6.4 0.48 10.8 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Atg14 PF10186.9 KKF94408.1 - 0.72 8.9 12.7 1.1 8.3 12.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF262 PF03235.14 KKF94408.1 - 0.91 9.7 6.5 1.1 9.4 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DDHD PF02862.17 KKF94408.1 - 2.6 8.2 6.6 3.3 7.8 6.6 1.2 1 0 0 1 1 1 0 DDHD domain Hydin_ADK PF17213.3 KKF94408.1 - 2.8 8.2 12.2 3.8 7.7 12.2 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SLC12 PF03522.15 KKF94408.1 - 4 6.3 11.5 4.7 6.1 11.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 KKF94408.1 - 5 5.1 9.7 5.8 4.9 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 KKF94408.1 - 5.7 6.9 6.2 6.8 6.7 6.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 KKF94408.1 - 6.2 6.5 18.9 8.4 6.1 18.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 KKF94408.1 - 7.4 5.8 15.1 9.2 5.5 15.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rtt106 PF08512.12 KKF94409.1 - 2.9e-06 27.6 0.1 4.1e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Nop14 PF04147.12 KKF94409.1 - 0.18 10.0 42.0 0.23 9.7 42.0 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KKF94409.1 - 1.7 7.9 36.6 2.2 7.5 36.6 1.1 1 0 0 1 1 1 0 BUD22 PRKCSH PF07915.13 KKF94411.1 - 5.8e-17 62.5 0.3 2e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein zf-BED PF02892.15 KKF94412.1 - 0.014 15.4 2.8 0.072 13.1 0.4 2.4 2 0 0 2 2 2 0 BED zinc finger ORC5_C PF14630.6 KKF94413.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus YL1 PF05764.13 KKF94413.1 - 0.37 10.9 4.6 0.55 10.3 4.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Amidohydro_2 PF04909.14 KKF94414.1 - 2.8e-09 37.2 0.0 7.5e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KKF94414.1 - 4.5e-05 22.9 0.0 0.00013 21.4 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family KH_1 PF00013.29 KKF94415.1 - 3.5e-49 164.5 12.6 6.7e-17 61.1 1.5 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KKF94415.1 - 3.2e-11 42.9 3.4 0.0042 16.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KKF94415.1 - 2.6e-09 36.8 1.0 0.055 13.3 0.0 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KKF94415.1 - 2.5e-07 30.6 0.0 0.1 12.6 0.0 3.3 3 0 0 3 3 3 3 KH-like RNA-binding domain KH_5 PF13184.6 KKF94415.1 - 0.0017 18.4 4.1 2.8 8.1 0.2 3.3 3 0 0 3 3 3 2 NusA-like KH domain 6PF2K PF01591.18 KKF94416.1 - 1.5e-78 263.1 2.1 2.4e-78 262.5 0.7 2.0 2 0 0 2 2 2 1 6-phosphofructo-2-kinase DEAD PF00270.29 KKF94416.1 - 2.9e-46 157.4 0.0 6.6e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase His_Phos_1 PF00300.22 KKF94416.1 - 2.7e-34 118.6 0.0 5.4e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Helicase_C PF00271.31 KKF94416.1 - 1e-23 83.8 0.0 9.7e-23 80.6 0.0 2.7 3 0 0 3 3 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKF94416.1 - 9.2e-18 64.2 0.3 4.7e-17 62.0 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) AAA_33 PF13671.6 KKF94416.1 - 5.7e-05 23.3 0.0 0.00019 21.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KKF94416.1 - 0.0001 22.3 0.0 0.0001 22.3 0.0 2.4 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit KTI12 PF08433.10 KKF94416.1 - 0.00051 19.6 0.1 0.001 18.6 0.1 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Cwf_Cwc_15 PF04889.12 KKF94416.1 - 0.0025 17.6 10.8 0.0025 17.6 10.8 1.8 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KKF94416.1 - 0.0033 15.8 8.8 0.0055 15.0 8.8 1.3 1 0 0 1 1 1 1 Nop14-like family AAA_30 PF13604.6 KKF94416.1 - 0.011 15.4 0.0 0.34 10.6 0.0 2.6 2 1 0 2 2 1 0 AAA domain MCM_bind PF09739.9 KKF94416.1 - 0.014 13.8 6.3 0.024 13.1 6.3 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Pox_Ag35 PF03286.14 KKF94416.1 - 0.015 15.1 13.5 0.034 13.9 13.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.12 KKF94416.1 - 0.028 13.8 8.1 0.045 13.1 8.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.13 KKF94416.1 - 0.032 14.1 13.7 3 7.7 0.1 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region ThuA PF06283.11 KKF94416.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Trehalose utilisation DUF816 PF05674.12 KKF94416.1 - 0.18 11.7 1.4 0.43 10.5 1.4 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) DNA_pol_phi PF04931.13 KKF94416.1 - 0.19 9.8 19.4 0.34 9.0 19.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF4820 PF16091.5 KKF94416.1 - 0.76 9.1 7.2 1.9 7.8 7.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RPN2_C PF18004.1 KKF94416.1 - 0.84 9.5 10.5 2.6 8.0 10.5 1.8 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 KKF94416.1 - 0.91 8.8 18.0 0.038 13.3 12.0 1.6 2 0 0 2 2 2 0 BUD22 FYDLN_acid PF09538.10 KKF94416.1 - 1.3 9.7 18.4 3.7 8.3 18.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.14 KKF94416.1 - 2.4 6.4 12.2 3.8 5.7 12.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 KKF94416.1 - 3.8 6.6 21.4 6.4 5.8 21.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF913 PF06025.12 KKF94416.1 - 3.9 6.3 6.4 6.5 5.6 6.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM60A PF15396.6 KKF94416.1 - 5.4 7.0 5.7 12 5.8 5.7 1.5 1 0 0 1 1 1 0 Protein Family FAM60A TFB6 PF17110.5 KKF94416.1 - 5.6 6.7 6.8 15 5.3 6.8 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 KKF94416.1 - 5.7 6.2 18.4 13 5.0 16.8 2.0 2 0 0 2 2 2 0 NOA36 protein Astro_capsid_p PF12226.8 KKF94416.1 - 8.9 5.3 17.8 18 4.3 17.8 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Asp PF00026.23 KKF94417.1 - 1.7e-31 109.9 0.2 3.2e-26 92.5 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KKF94417.1 - 6.7e-06 26.7 0.0 0.18 12.4 0.0 2.7 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KKF94417.1 - 0.044 14.3 0.0 16 6.1 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KKF94417.1 - 0.052 13.3 0.0 0.41 10.4 0.0 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal zf-C2H2 PF00096.26 KKF94418.1 - 0.0087 16.5 0.1 0.0087 16.5 0.1 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type Hid1 PF12722.7 KKF94418.1 - 1.3 7.0 5.6 1.6 6.8 5.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MAT1 PF06391.13 KKF94418.1 - 2.4 7.9 8.6 0.3 10.9 1.9 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 PAT1 PF09770.9 KKF94418.1 - 4 5.6 26.5 5.6 5.1 26.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2_4 PF13894.6 KKF94418.1 - 5.7 8.1 6.9 19 6.4 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Aminotran_1_2 PF00155.21 KKF94419.1 - 2e-63 214.8 0.0 2.4e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RabGAP-TBC PF00566.18 KKF94421.1 - 1e-48 165.8 0.1 3.1e-48 164.3 0.0 1.9 2 0 0 2 2 1 1 Rab-GTPase-TBC domain Mucin PF01456.17 KKF94421.1 - 0.0063 16.5 6.6 0.0063 16.5 6.6 2.1 2 0 0 2 2 1 1 Mucin-like glycoprotein DUF2353 PF09789.9 KKF94421.1 - 0.0063 15.9 14.3 0.16 11.3 8.3 2.5 2 0 0 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.9 KKF94421.1 - 0.0074 16.3 6.3 0.0074 16.3 6.3 3.6 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KKF94421.1 - 0.015 14.2 20.1 0.0079 15.1 5.2 3.6 3 0 0 3 3 3 0 Spc7 kinetochore protein SKA1 PF07160.12 KKF94421.1 - 0.08 12.8 6.3 0.12 12.2 2.1 3.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF1664 PF07889.12 KKF94421.1 - 0.14 12.2 7.5 0.041 13.9 2.1 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 KKF94421.1 - 0.18 11.1 24.5 0.017 14.4 9.0 3.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.18 KKF94421.1 - 0.24 11.8 7.8 4.2 7.8 0.1 3.9 4 0 0 4 4 3 0 TSC-22/dip/bun family V_ATPase_I PF01496.19 KKF94421.1 - 0.27 9.1 1.1 0.46 8.3 1.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med9 PF07544.13 KKF94421.1 - 0.35 11.0 11.9 1.4 9.0 6.3 3.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FapA PF03961.13 KKF94421.1 - 0.84 8.2 10.5 0.036 12.7 3.0 2.3 3 0 0 3 3 3 0 Flagellar Assembly Protein A TMPIT PF07851.13 KKF94421.1 - 1 8.5 6.1 2.9 7.0 6.1 1.7 1 0 0 1 1 1 0 TMPIT-like protein DUF641 PF04859.12 KKF94421.1 - 1.1 9.6 9.4 0.074 13.4 1.1 2.9 3 0 0 3 3 2 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 KKF94421.1 - 1.1 9.7 8.0 4.5 7.7 0.3 3.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 KKF94421.1 - 2 8.4 19.3 0.92 9.5 0.3 4.2 3 1 1 4 4 4 0 Prefoldin subunit NPV_P10 PF05531.12 KKF94421.1 - 2.1 8.8 8.9 0.68 10.4 0.2 3.7 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein CorA PF01544.18 KKF94421.1 - 2.3 7.5 13.4 0.016 14.5 3.4 2.3 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein PI3K_P85_iSH2 PF16454.5 KKF94421.1 - 2.5 7.7 14.9 0.091 12.4 4.7 3.1 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Leu_zip PF15294.6 KKF94421.1 - 3.2 7.2 15.0 0.03 13.9 2.8 3.3 4 0 0 4 4 4 0 Leucine zipper Filament PF00038.21 KKF94421.1 - 3.5 7.1 19.7 0.21 11.1 8.2 3.4 4 0 0 4 4 4 0 Intermediate filament protein CCDC144C PF14915.6 KKF94421.1 - 3.6 6.6 19.9 0.59 9.2 6.7 3.0 3 0 0 3 3 3 0 CCDC144C protein coiled-coil region Cnn_1N PF07989.11 KKF94421.1 - 5.1 7.3 19.7 4.5 7.5 0.3 4.3 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 HrpB7 PF09486.10 KKF94421.1 - 6 7.2 23.8 0.062 13.7 5.0 3.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.12 KKF94421.1 - 9.9 6.2 24.5 0.32 11.0 7.9 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Reticulon PF02453.17 KKF94422.1 - 2.5e-29 102.3 1.1 3e-29 102.0 1.1 1.1 1 0 0 1 1 1 1 Reticulon TRAP-gamma PF07074.12 KKF94422.1 - 0.013 15.0 0.2 0.028 14.0 0.2 1.5 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF1266 PF06889.11 KKF94422.1 - 0.016 15.3 0.0 0.45 10.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DNA_topoisoIV PF00521.20 KKF94423.1 - 5.6e-119 397.8 0.2 2e-118 396.0 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KKF94423.1 - 1.7e-45 154.4 2.3 1.7e-45 154.4 2.3 3.1 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KKF94423.1 - 5.2e-25 87.9 2.0 1.3e-24 86.7 2.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KKF94423.1 - 1.9e-12 47.7 0.0 5.1e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KKF94423.1 - 1.5e-06 28.3 0.0 6e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 Toprim domain TPR_2 PF07719.17 KKF94424.1 - 4.2e-08 32.7 0.7 0.094 12.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKF94424.1 - 6.1e-08 32.2 0.1 0.011 15.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKF94424.1 - 0.036 14.9 0.1 1.4 9.9 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF94424.1 - 0.045 14.0 0.5 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KKF94424.1 - 0.071 13.8 0.1 6.5 7.5 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKF94424.1 - 0.12 12.0 0.0 57 3.5 0.0 3.6 2 1 1 3 3 3 0 TPR repeat TPR_8 PF13181.6 KKF94424.1 - 0.13 12.6 0.2 17 5.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Inositol_P PF00459.25 KKF94425.1 - 2.9e-64 217.2 0.0 4.8e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family GST_N_3 PF13417.6 KKF94425.1 - 7.3e-17 61.5 0.0 2.3e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KKF94425.1 - 4.1e-15 55.9 0.0 9.9e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKF94425.1 - 4.5e-10 39.7 0.0 8.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 KKF94425.1 - 0.00013 22.3 0.0 0.00023 21.5 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KKF94425.1 - 0.002 18.9 0.0 0.0042 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 KKF94425.1 - 0.0076 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin His_Phos_2 PF00328.22 KKF94426.1 - 8.3e-62 209.7 0.0 1e-61 209.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Npa1 PF11707.8 KKF94427.1 - 6.7e-86 288.7 0.1 1.5e-85 287.6 0.1 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KKF94427.1 - 2.5e-51 174.1 1.7 6e-51 172.9 0.2 2.5 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Plug_translocon PF10559.9 KKF94428.1 - 0.16 11.8 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Plug domain of Sec61p PepSY_TM PF03929.16 KKF94428.1 - 3.2 7.3 7.2 9.5 5.8 7.2 1.8 1 0 0 1 1 1 0 PepSY-associated TM region Het-C PF07217.11 KKF94428.1 - 4.2 5.8 6.7 8.1 4.8 6.7 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Sec1 PF00995.23 KKF94429.1 - 1.3e-104 351.5 0.0 2.1e-84 284.8 0.1 2.0 2 0 0 2 2 2 2 Sec1 family adh_short PF00106.25 KKF94430.1 - 2.3e-15 56.6 0.0 3.6e-11 42.9 0.0 3.1 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKF94430.1 - 2.8e-08 33.6 0.0 1.4e-06 28.1 0.0 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF94430.1 - 8.4e-05 22.6 1.0 0.00063 19.7 0.0 2.4 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KKF94430.1 - 0.0039 16.7 0.0 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TMP_2 PF06791.13 KKF94430.1 - 0.074 12.7 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein Anticodon_1 PF08264.13 KKF94430.1 - 5 7.1 6.3 10 6.1 5.7 1.7 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA SUV3_C PF12513.8 KKF94431.1 - 5.7e-17 61.4 0.1 1.4e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KKF94431.1 - 2.4e-11 44.0 0.0 4.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KKF94431.1 - 1.1e-09 38.0 0.1 2e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Peptidase_C12 PF01088.21 KKF94432.1 - 9.9e-54 182.3 0.0 1.2e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Mannitol_dh_C PF08125.13 KKF94433.1 - 1.5e-42 145.8 0.3 2.3e-42 145.2 0.3 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KKF94433.1 - 7e-20 71.7 0.2 1.7e-19 70.5 0.0 1.7 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 KKF94433.1 - 0.0037 16.9 0.7 0.02 14.5 0.1 2.4 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KKF94433.1 - 0.035 13.7 0.0 0.23 11.1 0.0 2.3 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PGI PF00342.19 KKF94434.1 - 3.3e-230 764.7 0.3 3.8e-230 764.6 0.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Protoglobin PF11563.8 KKF94435.1 - 1.7e-56 190.5 1.6 2e-56 190.3 1.6 1.1 1 0 0 1 1 1 1 Protoglobin SatD PF16264.5 KKF94435.1 - 0.052 13.1 0.6 0.49 10.0 0.1 2.0 2 0 0 2 2 2 0 SatD family (SatD) Ferric_reduct PF01794.19 KKF94436.1 - 1.3e-19 70.5 14.9 2e-19 70.0 10.3 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KKF94436.1 - 2.1e-19 70.2 0.1 7.6e-17 61.9 0.0 2.8 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKF94436.1 - 2.5e-13 50.0 0.0 3.1e-12 46.6 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain Mito_carr PF00153.27 KKF94437.1 - 2.1e-24 85.2 8.7 4.9e-14 52.0 0.0 4.0 2 1 2 4 4 4 4 Mitochondrial carrier protein SAM_2 PF07647.17 KKF94438.1 - 6.1e-09 35.9 0.1 1.4e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KKF94438.1 - 1.3e-05 25.6 0.3 2.4e-05 24.7 0.3 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KKF94438.1 - 0.0022 18.1 0.7 0.011 15.8 0.2 2.3 2 0 0 2 2 2 1 IGR protein motif DUF4508 PF14969.6 KKF94438.1 - 0.062 13.6 0.4 0.21 11.9 0.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) CBF PF03914.17 KKF94439.1 - 1.2e-48 165.4 0.2 1.2e-48 165.4 0.2 3.1 2 1 0 2 2 2 1 CBF/Mak21 family Borrelia_P83 PF05262.11 KKF94439.1 - 3.1 6.2 26.7 6 5.2 26.7 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein VIR_N PF15912.5 KKF94439.1 - 5 6.6 28.3 4.5 6.8 18.1 2.8 2 0 0 2 2 2 0 Virilizer, N-terminal PA26 PF04636.13 KKF94439.1 - 5.5 5.8 12.2 13 4.6 12.2 1.6 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ALMT PF11744.8 KKF94439.1 - 5.9 5.6 9.8 15 4.3 9.8 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter tRNA-synt_2b PF00587.25 KKF94440.1 - 7.3e-19 68.4 0.0 1.5e-18 67.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKF94440.1 - 4.5e-08 33.1 0.0 9.3e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Prefoldin PF02996.17 KKF94441.1 - 9.4e-22 77.2 3.0 9.4e-22 77.2 3.0 1.7 2 0 0 2 2 2 1 Prefoldin subunit PHM7_cyt PF14703.6 KKF94441.1 - 0.0054 17.0 2.9 0.0095 16.2 2.9 1.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter CppA_C PF14507.6 KKF94441.1 - 0.013 16.2 7.5 1.2 9.9 0.2 3.1 2 1 1 3 3 3 0 CppA C-terminal Prefoldin_2 PF01920.20 KKF94441.1 - 0.014 15.3 9.8 0.02 14.9 1.8 2.8 3 0 0 3 3 3 0 Prefoldin subunit DUF5402 PF17393.2 KKF94441.1 - 0.039 13.9 0.2 11 6.0 0.0 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5402) Sec2p PF06428.11 KKF94441.1 - 0.23 11.4 10.1 6.5 6.8 2.1 3.2 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Med30 PF11315.8 KKF94441.1 - 0.32 11.2 6.0 0.68 10.1 0.0 2.6 3 0 0 3 3 3 0 Mediator complex subunit 30 Fib_alpha PF08702.10 KKF94441.1 - 0.38 10.9 9.0 4.2 7.5 5.5 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family QLQ PF08880.11 KKF94441.1 - 0.81 9.5 5.9 12 5.7 0.6 2.6 2 0 0 2 2 2 0 QLQ DUF3697 PF12478.8 KKF94441.1 - 1.1 9.5 4.1 23 5.2 0.3 2.5 2 0 0 2 2 2 0 Ubiquitin-associated protein 2 CLZ PF16526.5 KKF94441.1 - 1.3 9.4 7.1 0.88 10.0 0.4 2.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TACC_C PF05010.14 KKF94441.1 - 1.6 8.5 12.5 2.3 8.0 2.4 2.7 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Peptidase_S49_N PF08496.10 KKF94441.1 - 4.3 7.4 10.6 3.6 7.6 2.7 2.7 1 1 1 3 3 3 0 Peptidase family S49 N-terminal DUF1192 PF06698.11 KKF94441.1 - 6.1 7.0 10.3 3.1 7.9 1.5 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) 4HBT PF03061.22 KKF94443.1 - 6.8e-10 39.2 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily HAMP_N3 PF18575.1 KKF94443.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 HAMP N-terminal domain 3 APS_kinase PF01583.20 KKF94444.1 - 2.3e-72 242.1 0.0 2.8e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KKF94444.1 - 3.4e-07 30.5 0.0 5.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKF94444.1 - 0.00069 20.2 0.0 0.0011 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KKF94444.1 - 0.0036 16.8 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 KKF94444.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KKF94444.1 - 0.097 13.0 0.1 0.15 12.4 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KKF94444.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF463 PF04317.12 KKF94444.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 V-ATPase_C PF03223.15 KKF94445.1 - 2.1e-123 412.4 0.4 2.5e-123 412.2 0.4 1.0 1 0 0 1 1 1 1 V-ATPase subunit C YfkD PF14167.6 KKF94445.1 - 0.04 13.1 0.1 0.096 11.9 0.0 1.6 2 0 0 2 2 2 0 YfkD-like protein LemA PF04011.12 KKF94445.1 - 1.1 9.1 4.4 0.36 10.7 0.8 1.9 2 1 0 2 2 2 0 LemA family F-box PF00646.33 KKF94447.1 - 1.1e-09 37.9 0.3 2.6e-09 36.7 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KKF94447.1 - 1.6e-09 37.5 1.8 1.8e-09 37.4 0.2 2.0 2 0 0 2 2 2 1 F-box-like Nup84_Nup100 PF04121.13 KKF94449.1 - 5.2e-165 550.5 0.0 7.1e-165 550.1 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Mod_r PF07200.13 KKF94449.1 - 2.9e-27 95.6 4.3 7e-27 94.3 4.3 1.7 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Rad60-SLD PF11976.8 KKF94450.1 - 1.1e-18 66.7 0.2 1.7e-18 66.2 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KKF94450.1 - 2.2e-11 43.3 0.1 3.9e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.12 KKF94450.1 - 0.012 16.0 0.1 0.016 15.6 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) LIM PF00412.22 KKF94451.1 - 5e-18 65.1 16.3 8e-09 35.6 5.9 2.4 2 0 0 2 2 2 2 LIM domain DUF2321 PF10083.9 KKF94451.1 - 0.0031 17.1 0.3 0.0031 17.1 0.3 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2321) RTBV_P12 PF06361.11 KKF94451.1 - 0.083 13.3 0.4 0.19 12.1 0.4 1.5 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein Nudix_N_2 PF14803.6 KKF94451.1 - 2.7 8.0 13.9 3.3 7.7 1.9 4.0 4 0 0 4 4 4 0 Nudix N-terminal Dynamin_M PF01031.20 KKF94452.1 - 1e-110 369.5 0.0 1.6e-110 368.8 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KKF94452.1 - 1.4e-56 191.2 0.0 2.9e-56 190.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KKF94452.1 - 3.6e-31 107.2 1.0 8.7e-31 105.9 1.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KKF94452.1 - 6e-05 23.1 0.4 0.00055 20.0 0.4 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2380 PF09533.10 KKF94453.1 - 0.06 13.0 0.1 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Ribosomal_L6 PF00347.23 KKF94454.1 - 1.8e-27 95.8 9.5 1.7e-14 54.2 2.8 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Podoplanin PF05808.11 KKF94455.1 - 0.01 15.9 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 Podoplanin GCV_T PF01571.21 KKF94456.1 - 5.3e-76 255.4 0.0 7.1e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain V-ATPase_H_N PF03224.14 KKF94456.1 - 8.4e-61 206.0 0.0 2.4e-46 158.5 0.0 2.2 1 1 1 2 2 2 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 KKF94456.1 - 4.5e-31 107.4 0.0 1.3e-30 105.9 0.0 1.8 1 0 0 1 1 1 1 V-ATPase subunit H GCV_T_C PF08669.11 KKF94456.1 - 5.4e-23 80.7 0.1 9.8e-23 79.9 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 KKF94456.1 - 0.0015 18.7 0.1 0.34 11.0 0.0 2.6 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family Metallophos PF00149.28 KKF94457.1 - 1.7e-06 28.7 0.3 3.5e-06 27.7 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5636 PF18686.1 KKF94457.1 - 1.1 9.4 9.1 17 5.6 1.4 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF5636) Ofd1_CTDD PF10637.9 KKF94458.1 - 3.1e-91 305.3 0.0 3e-87 292.2 0.0 2.4 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KKF94458.1 - 3.6e-24 85.2 0.0 1.8e-23 83.0 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KKF94458.1 - 1.1e-12 48.6 0.0 2.9e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribul_P_3_epim PF00834.19 KKF94459.1 - 1.7e-63 213.6 0.0 2.2e-62 210.0 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 KKF94459.1 - 0.11 12.1 0.1 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TPR_14 PF13428.6 KKF94460.1 - 4.5e-07 30.1 0.1 3.9 8.5 0.0 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKF94460.1 - 0.036 14.6 0.0 0.18 12.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKF94460.1 - 0.13 12.9 0.0 6.3 7.5 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Suf PF05843.14 KKF94460.1 - 1.1 9.2 7.1 30 4.5 0.4 3.6 2 1 0 3 3 3 0 Suppressor of forked protein (Suf) peroxidase PF00141.23 KKF94461.1 - 1.6e-50 171.9 0.0 2.7e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF1972 PF09314.11 KKF94461.1 - 0.16 11.5 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) Molybdopterin PF00384.22 KKF94461.1 - 0.16 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin oxidoreductase CRC_subunit PF08624.10 KKF94462.1 - 1.8e-08 34.9 0.2 2.8e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PI-PLC-X PF00388.19 KKF94463.1 - 1.7e-58 196.3 0.0 3.5e-58 195.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KKF94463.1 - 7.5e-45 152.0 0.1 2e-44 150.6 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KKF94463.1 - 0.0012 19.0 0.1 0.0075 16.5 0.1 2.3 1 1 0 1 1 1 1 C2 domain Tau95 PF09734.9 KKF94464.1 - 1.4e-37 129.6 1.7 5.7e-37 127.6 0.7 2.1 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain NOA36 PF06524.12 KKF94464.1 - 0.51 9.6 29.8 1.9 7.7 9.6 2.2 2 0 0 2 2 2 0 NOA36 protein CCDC53 PF10152.9 KKF94464.1 - 1.5 9.3 7.4 0.28 11.6 0.5 2.6 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex FAM176 PF14851.6 KKF94464.1 - 1.7 8.3 17.7 0.33 10.6 3.4 2.2 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 KKF94464.1 - 4 7.4 22.5 0.52 10.3 6.2 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 KKF94464.1 - 4.7 6.9 24.3 2.7 7.7 6.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Prothymosin PF03247.14 KKF94464.1 - 5.7 7.4 32.5 0.65 10.5 9.6 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family B56 PF01603.20 KKF94465.1 - 6.5e-179 595.2 3.7 9.8e-179 594.6 3.7 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KKF94465.1 - 0.00011 22.2 1.2 0.34 10.8 0.4 2.5 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Ndc1_Nup PF09531.10 KKF94465.1 - 1.6 7.4 4.5 2.2 6.9 4.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF737 PF05300.11 KKF94465.1 - 3.5 7.9 5.9 0.47 10.8 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF737) CTD_bind PF04818.13 KKF94466.1 - 8.6e-15 55.3 0.2 2.5e-14 53.8 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF4748 PF15932.5 KKF94467.1 - 2.1e-22 78.6 0.6 2.5e-22 78.4 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) MGS PF02142.22 KKF94467.1 - 0.12 12.5 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 MGS-like domain Exo_endo_phos PF03372.23 KKF94468.1 - 1e-08 35.0 0.2 2.1e-08 34.0 0.1 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_76 PF03663.14 KKF94469.1 - 4.1e-148 493.8 20.9 4.7e-148 493.6 20.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Dak1 PF02733.17 KKF94470.1 - 8.2e-105 350.1 7.0 1.3e-104 349.5 7.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KKF94470.1 - 4.7e-45 153.6 0.0 1.2e-44 152.3 0.0 1.7 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.22 KKF94471.1 - 4.3e-18 64.8 0.1 5.9e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KKF94471.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein ECH_2 PF16113.5 KKF94472.1 - 2.2e-120 402.2 0.0 3.2e-120 401.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KKF94472.1 - 7.3e-27 94.3 0.1 3.4e-24 85.5 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Acetate_kinase PF00871.17 KKF94472.1 - 0.0043 15.8 0.1 0.0095 14.7 0.1 1.7 1 1 0 1 1 1 1 Acetokinase family Pol_alpha_B_N PF08418.10 KKF94473.1 - 1.5e-68 231.5 0.0 1.5e-68 231.5 0.0 3.4 3 1 0 3 3 3 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KKF94473.1 - 1e-13 51.2 0.0 2.7e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B GATA PF00320.27 KKF94473.1 - 0.074 12.7 13.1 0.057 13.0 1.3 3.0 3 0 0 3 3 3 0 GATA zinc finger MFAP1 PF06991.11 KKF94474.1 - 5.1e-65 219.4 26.8 5.1e-65 219.4 26.8 2.2 2 0 0 2 2 2 2 Microfibril-associated/Pre-mRNA processing Alb1 PF09135.11 KKF94475.1 - 2.4e-23 83.0 8.7 3.4e-23 82.5 8.7 1.2 1 0 0 1 1 1 1 Alb1 TMF_TATA_bd PF12325.8 KKF94475.1 - 0.054 13.7 0.0 0.076 13.2 0.0 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding BRCT PF00533.26 KKF94476.1 - 3.6e-05 24.1 0.0 0.00011 22.5 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 KKF94476.1 - 0.00015 21.8 0.0 0.53 10.4 0.0 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KKF94476.1 - 0.0051 16.7 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain RraA-like PF03737.15 KKF94476.1 - 0.052 13.7 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 Aldolase/RraA BRCT_2 PF16589.5 KKF94476.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.9 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Glyco_hydro_18 PF00704.28 KKF94477.1 - 3.8e-08 33.4 0.0 6.3e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 GerD PF17898.1 KKF94478.1 - 0.14 12.1 0.5 4.5 7.3 0.1 2.3 1 1 1 2 2 2 0 Spore germination GerD central core domain AAR2 PF05282.11 KKF94479.1 - 1.9e-05 24.3 0.1 2.1e-05 24.1 0.1 1.0 1 0 0 1 1 1 1 AAR2 protein GHMP_kinases_N PF00288.26 KKF94479.1 - 0.074 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 GHMP kinases N terminal domain DUF3824 PF12868.7 KKF94480.1 - 0.014 16.1 17.1 0.014 16.1 17.1 3.9 2 1 2 4 4 4 0 Domain of unknwon function (DUF3824) Glyco_transf_20 PF00982.21 KKF94481.1 - 3.2e-141 471.3 0.0 4.4e-141 470.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KKF94481.1 - 1e-71 240.8 0.0 1.8e-71 240.0 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Inh PF02974.14 KKF94481.1 - 0.074 13.1 0.5 0.34 11.0 0.5 2.1 1 0 0 1 1 1 0 Protease inhibitor Inh SNF2_N PF00176.23 KKF94482.1 - 2.2e-56 191.1 0.0 3.8e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KKF94482.1 - 8.9e-52 175.9 0.5 1.8e-51 174.9 0.5 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 KKF94482.1 - 1.4e-15 57.6 0.0 3.4e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF94482.1 - 8.2e-08 32.4 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKF94482.1 - 0.00025 20.3 0.0 0.0018 17.5 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KKF94482.1 - 0.085 12.5 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Bromodomain PF00439.25 KKF94483.1 - 8.7e-36 121.9 0.0 4e-19 68.5 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KKF94483.1 - 1.8e-20 73.0 0.1 1e-19 70.6 0.1 2.2 2 0 0 2 2 2 1 BAH domain HTH_32 PF13565.6 KKF94483.1 - 0.45 11.2 4.9 5.8 7.6 0.8 3.5 3 0 0 3 3 3 0 Homeodomain-like domain BSP_II PF05432.11 KKF94483.1 - 3.3 7.3 16.8 1.1 8.9 3.9 3.2 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) Nucleo_P87 PF07267.11 KKF94483.1 - 4.2 6.1 13.0 0.081 11.8 1.9 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Glyco_transf_24 PF18404.1 KKF94484.1 - 5e-147 488.4 2.5 8e-147 487.8 2.5 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KKF94484.1 - 5.9e-56 190.3 0.1 2e-55 188.5 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KKF94484.1 - 9.1e-47 159.7 0.1 2.5e-46 158.3 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KKF94484.1 - 4.9e-40 136.0 0.0 1.1e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 KKF94484.1 - 4.4e-39 134.3 0.0 1e-38 133.1 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KKF94484.1 - 8.3e-39 132.6 4.9 1e-37 129.1 0.2 3.2 4 0 0 4 4 4 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KKF94484.1 - 6.1e-07 29.3 0.2 2.5e-06 27.3 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 Coatomer_WDAD PF04053.14 KKF94485.1 - 2.7e-144 481.5 0.0 5e-144 480.7 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KKF94485.1 - 1.4e-97 327.0 0.0 1.9e-97 326.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KKF94485.1 - 5.6e-36 121.9 21.1 6e-08 33.2 0.2 8.0 8 1 1 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94485.1 - 2.4e-08 34.1 1.2 0.0014 18.9 0.1 5.0 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKF94485.1 - 0.0023 16.7 7.1 0.13 10.8 0.1 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Amidohydro_3 PF07969.11 KKF94486.1 - 1.2e-65 222.9 13.2 1.3e-65 222.7 13.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KKF94486.1 - 1.8e-09 37.4 2.2 1.1e-05 25.0 0.8 2.7 2 1 0 2 2 2 2 Amidohydrolase family zf-CCHC PF00098.23 KKF94487.1 - 8.2e-06 25.7 2.1 1.8e-05 24.6 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 KKF94487.1 - 0.0024 17.6 0.9 0.0038 16.9 0.9 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 KKF94487.1 - 0.025 14.3 0.1 0.081 12.7 0.0 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 KKF94487.1 - 0.14 12.2 5.0 0.25 11.3 5.0 1.5 1 0 0 1 1 1 0 Zinc knuckle WD40 PF00400.32 KKF94488.1 - 7.1e-09 36.2 5.8 0.00086 20.1 0.2 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94488.1 - 0.00022 21.4 0.2 1.4 9.2 0.1 4.1 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_N PF01194.17 KKF94489.1 - 7.2e-30 103.1 0.8 8.3e-30 102.9 0.8 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Dynein_light PF01221.18 KKF94491.1 - 5.7e-40 135.5 1.4 6.5e-40 135.3 1.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.22 KKF94492.1 - 3.9e-59 196.4 2.7 1.3e-17 63.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKF94492.1 - 3.2e-06 26.7 0.0 0.053 13.1 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KKF94492.1 - 0.00013 21.9 0.5 10 6.3 0.0 4.7 4 0 0 4 4 4 1 Limkain b1 RRM_occluded PF16842.5 KKF94492.1 - 0.0002 21.1 0.1 6 6.8 0.0 4.6 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KKF94492.1 - 0.0012 18.6 0.7 6.9 6.4 0.0 4.2 4 0 0 4 4 4 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KKF94492.1 - 0.0072 16.4 0.0 20 5.4 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif Phage_TAC_13 PF16459.5 KKF94492.1 - 0.038 14.4 0.2 2 8.9 0.0 3.3 3 0 0 3 3 3 0 Phage tail assembly chaperone, TAC PHM7_cyt PF14703.6 KKF94492.1 - 0.69 10.1 5.1 28 4.9 0.2 4.1 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter TEA PF01285.18 KKF94493.1 - 2.8e-17 62.6 0.3 6e-17 61.5 0.3 1.5 1 0 0 1 1 1 1 TEA/ATTS domain zf-RING_2 PF13639.6 KKF94494.1 - 7.1e-10 39.1 0.2 1.2e-09 38.3 0.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KKF94494.1 - 1.1e-08 34.6 0.8 1.7e-08 34.0 0.8 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKF94494.1 - 4.4e-07 29.6 0.2 7e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKF94494.1 - 1.2e-05 25.1 0.1 2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKF94494.1 - 8.8e-05 22.7 2.8 0.00055 20.2 2.8 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KKF94494.1 - 0.00019 21.4 0.3 0.00035 20.5 0.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKF94494.1 - 0.0004 20.3 0.0 0.00064 19.6 0.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain PHD PF00628.29 KKF94494.1 - 0.0053 16.6 0.1 0.0097 15.8 0.1 1.4 1 0 0 1 1 1 1 PHD-finger Zn_ribbon_17 PF17120.5 KKF94494.1 - 0.031 13.9 0.1 0.054 13.1 0.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 KKF94494.1 - 0.057 13.4 2.7 0.097 12.6 2.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KKF94494.1 - 0.06 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KKF94494.1 - 0.088 12.9 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SOG2 PF10428.9 KKF94494.1 - 0.094 11.9 2.8 0.1 11.8 2.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NACHT PF05729.12 KKF94495.1 - 4.7e-20 72.2 0.0 7.3e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KKF94495.1 - 8.8e-05 22.9 0.0 0.00017 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KKF94495.1 - 0.00029 21.2 0.0 0.00087 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKF94495.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Patatin PF01734.22 KKF94495.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase ATPase_2 PF01637.18 KKF94495.1 - 0.022 14.7 0.0 0.05 13.5 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KKF94495.1 - 0.036 13.9 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RasGEF_N_2 PF14663.6 KKF94495.1 - 0.093 13.1 0.1 0.48 10.8 0.0 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HTH_28 PF13518.6 KKF94495.1 - 0.094 12.9 0.0 26 5.0 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain TsaE PF02367.17 KKF94495.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GvpD PF07088.11 KKF94495.1 - 0.13 10.8 0.0 0.25 9.9 0.0 1.4 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA PF00004.29 KKF94495.1 - 0.16 12.4 0.0 0.72 10.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PCI PF01399.27 KKF94496.1 - 1.9e-13 50.9 0.0 2.4e-12 47.3 0.0 2.6 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KKF94496.1 - 3.4e-08 33.0 2.3 3.4e-08 33.0 2.3 2.2 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix MscS_porin PF12795.7 KKF94496.1 - 0.5 9.9 12.8 0.11 12.0 0.4 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Pkinase PF00069.25 KKF94497.1 - 1.7e-35 122.7 0.5 2.7e-35 122.0 0.5 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF94497.1 - 2e-24 86.3 0.1 3.4e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KKF94497.1 - 8.5e-09 35.6 0.0 3.2e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 KKF94497.1 - 0.00079 18.8 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KKF94497.1 - 0.0024 17.5 0.2 0.0043 16.7 0.2 1.4 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 KKF94497.1 - 0.065 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ArfGap PF01412.18 KKF94498.1 - 1.2e-33 115.6 0.0 1.2e-33 115.6 0.0 2.4 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KKF94498.1 - 9.4e-23 81.1 19.4 1.5e-22 80.5 19.4 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KKF94498.1 - 1.5e-12 47.9 0.2 3.3e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 PH domain DUF5082 PF16888.5 KKF94498.1 - 0.064 13.5 1.6 0.22 11.8 1.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) PH_9 PF15410.6 KKF94498.1 - 0.25 11.7 4.8 1.2 9.6 0.9 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain SmAKAP PF15127.6 KKF94498.1 - 0.33 12.2 1.7 1.5 10.1 1.7 2.1 1 0 0 1 1 1 0 Small membrane A-kinase anchor protein YabA PF06156.13 KKF94498.1 - 7.2 7.3 8.1 11 6.7 0.2 3.1 2 1 1 3 3 3 0 Initiation control protein YabA C2 PF00168.30 KKF94499.1 - 1.2e-15 57.7 0.0 2.8e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 KKF94499.1 - 2.4e-15 57.0 6.3 3.1e-13 50.1 2.8 3.2 2 1 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 KKF94499.1 - 4e-05 22.4 1.0 6.1e-05 21.8 0.3 1.5 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) DUF2709 PF10915.8 KKF94499.1 - 0.017 14.4 0.5 0.017 14.4 0.5 2.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2709) Peptidase_M3 PF01432.20 KKF94500.1 - 4.2e-120 402.1 0.0 5.7e-120 401.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KKF94500.1 - 0.046 13.3 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like WcbI PF18588.1 KKF94500.1 - 0.067 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI SKA2 PF16740.5 KKF94500.1 - 0.72 9.7 2.4 1.9 8.3 0.3 2.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 ApoO PF09769.9 KKF94501.1 - 2.2e-40 137.6 0.3 9.7e-40 135.5 0.1 2.0 2 0 0 2 2 2 1 Apolipoprotein O Dus PF01207.17 KKF94502.1 - 1.1e-47 162.7 0.0 6.5e-47 160.1 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyrophosphatase PF00719.19 KKF94503.1 - 1.6e-57 193.8 0.1 2.1e-57 193.4 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sec20 PF03908.13 KKF94504.1 - 1.3e-15 57.1 0.2 3.1e-15 55.8 0.2 1.7 1 0 0 1 1 1 1 Sec20 DASH_Dam1 PF08653.10 KKF94504.1 - 1.2 9.0 3.4 6.1 6.7 0.0 3.2 3 1 0 3 3 3 0 DASH complex subunit Dam1 DUF3584 PF12128.8 KKF94504.1 - 1.4 6.3 6.2 7.2 4.0 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Aldolase_II PF00596.21 KKF94505.1 - 2.4e-44 151.5 0.0 3e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain RAP1 PF07218.11 KKF94506.1 - 6.4 4.9 17.9 6.9 4.8 17.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Calreticulin PF00262.18 KKF94507.1 - 6.3e-159 528.7 16.8 7.9e-159 528.4 16.8 1.1 1 0 0 1 1 1 1 Calreticulin family OAD_gamma PF04277.13 KKF94507.1 - 0.36 11.4 0.1 0.36 11.4 0.1 3.4 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S9 PF00326.21 KKF94508.1 - 3.2e-54 183.6 0.0 5.3e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KKF94508.1 - 0.00013 20.8 0.0 0.014 14.1 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PD40 PF07676.12 KKF94508.1 - 0.00059 19.7 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Nop52 PF05997.12 KKF94509.1 - 6e-53 179.8 0.0 1.8e-52 178.3 0.0 1.6 1 1 0 1 1 1 1 Nucleolar protein,Nop52 DAGK_cat PF00781.24 KKF94510.1 - 8.3e-10 38.4 0.0 1.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF1990 PF09348.10 KKF94511.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) AAA-ATPase_like PF09820.9 KKF94511.1 - 0.39 10.1 4.9 0.28 10.6 1.9 2.2 1 1 1 2 2 2 0 Predicted AAA-ATPase KH_1 PF00013.29 KKF94513.1 - 1.2e-44 149.9 6.7 2e-18 66.0 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KKF94513.1 - 8.3e-13 48.0 3.7 0.004 16.9 0.3 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KKF94513.1 - 4.7e-06 26.5 0.0 0.022 14.7 0.0 3.3 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_4 PF13083.6 KKF94513.1 - 1.3e-05 25.0 1.4 1.1 9.2 0.2 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KKF94513.1 - 0.00017 21.6 9.1 0.16 12.0 0.3 3.5 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.19 KKF94514.1 - 3.8e-44 149.5 0.0 6.2e-44 148.8 0.0 1.4 1 0 0 1 1 1 1 dUTPase CENP-K PF11802.8 KKF94514.1 - 0.0016 18.0 1.6 0.12 11.9 2.9 2.2 2 0 0 2 2 2 1 Centromere-associated protein K DCD PF06559.11 KKF94514.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) PCNA_N PF00705.18 KKF94515.1 - 1.1e-55 186.7 3.9 1.7e-55 186.2 3.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KKF94515.1 - 1.2e-46 158.0 0.1 4.7e-46 156.1 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Phos_pyr_kin PF08543.12 KKF94515.1 - 4.5e-10 39.3 0.0 7.7e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Rad9 PF04139.13 KKF94515.1 - 4.8e-09 36.0 0.0 7.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Rad9 PfkB PF00294.24 KKF94515.1 - 7e-07 28.8 0.1 2.2e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Rad1 PF02144.16 KKF94515.1 - 1.7e-06 27.3 0.3 4.7e-05 22.6 0.3 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KKF94515.1 - 0.0016 17.6 0.1 0.0039 16.3 0.1 1.7 2 0 0 2 2 2 1 Hus1-like protein p450 PF00067.22 KKF94516.1 - 2.9e-72 243.9 0.0 3.7e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3045 PF11243.8 KKF94516.1 - 0.19 11.9 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) TAFII55_N PF04658.13 KKF94517.1 - 1.9e-47 160.9 0.1 5.9e-47 159.4 0.0 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region CENP-B_dimeris PF09026.10 KKF94517.1 - 0.024 15.0 8.3 0.024 15.0 8.3 3.0 2 1 0 2 2 2 0 Centromere protein B dimerisation domain TSC22 PF01166.18 KKF94517.1 - 1.6 9.1 5.3 0.51 10.7 1.1 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family FAM76 PF16046.5 KKF94517.1 - 3.5 6.9 7.1 0.62 9.4 3.7 1.5 2 0 0 2 2 2 0 FAM76 protein Mif2_N PF15624.6 KKF94517.1 - 5.9 7.6 10.8 0.14 12.8 1.9 2.5 2 1 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Ribosomal_L37 PF08561.10 KKF94518.1 - 1.6e-39 135.2 1.1 2.3e-39 134.6 1.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 NDUFB10 PF10249.9 KKF94519.1 - 0.0029 18.1 0.0 0.0032 18.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 RRM_1 PF00076.22 KKF94520.1 - 1.5e-35 120.8 0.0 1.6e-17 63.0 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKF94520.1 - 7.1e-06 25.9 0.0 0.00076 19.4 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KKF94520.1 - 0.00032 20.7 0.4 0.19 11.9 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif AAA_16 PF13191.6 KKF94521.1 - 0.013 15.9 0.0 0.051 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KKF94521.1 - 0.036 14.0 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KKF94521.1 - 0.094 12.7 0.0 0.55 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 KKF94523.1 - 2.1e-109 365.4 35.0 7.1e-55 186.6 10.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKF94523.1 - 4.4e-68 228.1 0.0 8.7e-34 117.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKF94523.1 - 4.1e-13 49.3 0.3 0.00024 20.6 0.0 3.9 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKF94523.1 - 2e-06 27.8 0.1 0.079 12.9 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KKF94523.1 - 2.1e-06 27.4 3.7 0.0052 16.5 0.8 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KKF94523.1 - 9.4e-06 24.7 5.0 0.0063 15.4 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KKF94523.1 - 2.7e-05 24.6 10.3 0.014 15.8 0.1 4.0 3 2 0 4 4 3 2 AAA ATPase domain AAA_15 PF13175.6 KKF94523.1 - 6.2e-05 22.9 0.0 0.33 10.6 0.0 2.5 3 0 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 KKF94523.1 - 9.8e-05 22.0 0.2 0.17 11.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KKF94523.1 - 0.00012 22.5 2.3 2.7 8.4 0.1 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KKF94523.1 - 0.00024 21.0 0.2 0.28 10.9 0.0 3.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KKF94523.1 - 0.00065 19.5 0.9 2.6 7.7 0.1 3.6 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 KKF94523.1 - 0.00072 19.9 2.3 0.51 10.6 0.1 3.5 2 2 0 2 2 2 1 AAA domain G-alpha PF00503.20 KKF94523.1 - 0.0039 16.4 0.0 2.2 7.4 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 KKF94523.1 - 0.0039 17.4 1.4 5.8 7.2 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 KKF94523.1 - 0.0045 17.3 1.3 0.64 10.3 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KKF94523.1 - 0.0058 16.8 0.0 5.1 7.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KKF94523.1 - 0.0066 15.7 0.0 2 7.7 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 KKF94523.1 - 0.01 15.8 0.1 12 5.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KKF94523.1 - 0.013 15.0 0.0 6 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KKF94523.1 - 0.019 15.1 3.0 3.9 7.5 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 KKF94523.1 - 0.039 14.5 0.0 13 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KKF94523.1 - 0.063 12.9 0.0 3.5 7.2 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.25 KKF94523.1 - 0.086 12.5 0.2 17 5.0 0.0 2.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 KKF94523.1 - 0.22 11.4 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 KKF94523.1 - 0.27 11.7 5.5 4.4 7.8 0.1 3.5 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KKF94523.1 - 1.6 8.9 4.4 18 5.4 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase Glyco_hydro_16 PF00722.21 KKF94525.1 - 3e-07 30.1 0.0 3.4e-06 26.6 0.0 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_transf_34 PF05637.12 KKF94526.1 - 6.2e-66 222.5 0.5 8.6e-66 222.1 0.5 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ribosomal_S28e PF01200.18 KKF94527.1 - 4.3e-31 106.7 3.1 5.1e-31 106.5 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Dynamitin PF04912.14 KKF94528.1 - 2e-102 343.5 19.4 2.3e-102 343.3 19.4 1.0 1 0 0 1 1 1 1 Dynamitin DUF16 PF01519.16 KKF94528.1 - 0.0027 18.2 6.0 0.026 15.0 0.3 3.4 3 0 0 3 3 3 1 Protein of unknown function DUF16 Laminin_II PF06009.12 KKF94528.1 - 0.0036 17.3 15.9 0.0045 17.0 0.6 4.3 4 1 1 5 5 5 2 Laminin Domain II MRPL52 PF18699.1 KKF94528.1 - 0.02 15.0 2.9 0.02 15.0 2.9 2.8 4 0 0 4 4 4 0 Mitoribosomal protein mL52 SKA1 PF07160.12 KKF94528.1 - 0.053 13.4 13.1 1.8 8.3 0.3 3.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 ATF7IP_BD PF16788.5 KKF94528.1 - 0.06 13.4 2.1 0.072 13.2 0.2 2.1 2 0 0 2 2 2 0 ATF-interacting protein binding domain NPV_P10 PF05531.12 KKF94528.1 - 0.081 13.4 6.5 6.6 7.3 0.1 4.6 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 KKF94528.1 - 0.13 12.6 14.6 0.23 11.8 0.4 4.1 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FH2 PF02181.23 KKF94528.1 - 0.29 10.2 9.5 0.48 9.5 0.3 3.0 3 0 0 3 3 3 0 Formin Homology 2 Domain Cytochrom_B562 PF07361.11 KKF94528.1 - 1.1 9.9 8.1 3.4 8.4 0.7 3.4 3 0 0 3 3 3 0 Cytochrome b562 DUF1664 PF07889.12 KKF94528.1 - 1.4 9.0 9.1 5.5 7.0 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KKF94528.1 - 2.5 7.9 13.9 0.2 11.5 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Spore_III_AB PF09548.10 KKF94528.1 - 3.3 7.8 9.2 1.8 8.7 1.4 3.2 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF948 PF06103.11 KKF94528.1 - 7.5 6.9 7.0 3.7 7.9 0.3 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GCIP PF13324.6 KKF94529.1 - 0.25 10.9 5.1 0.27 10.8 5.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KKF94529.1 - 0.37 10.1 5.0 0.4 10.0 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein Merozoite_SPAM PF07133.11 KKF94529.1 - 0.54 10.2 15.3 0.62 10.0 15.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 KKF94529.1 - 1.4 7.1 8.2 1.4 7.1 8.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Alpha-amylase PF00128.24 KKF94530.1 - 2.7e-116 388.8 0.0 3.3e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KKF94530.1 - 0.048 12.8 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain PP2C PF00481.21 KKF94531.1 - 2.3e-53 181.4 0.0 3.6e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KKF94531.1 - 3.7e-32 109.9 52.4 5.9e-09 35.6 0.1 10.0 4 3 6 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 KKF94531.1 - 5.9e-32 109.2 58.3 1.7e-05 25.1 0.1 13.8 8 3 7 16 16 16 13 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KKF94531.1 - 1.2e-29 103.2 0.0 9.8e-29 100.3 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 KKF94531.1 - 1.3e-06 28.2 44.2 2.6 8.9 0.0 14.8 16 1 0 16 16 16 2 Leucine Rich Repeat LRR_9 PF14580.6 KKF94531.1 - 0.011 15.3 18.8 0.49 9.9 0.8 4.7 2 1 1 4 4 4 0 Leucine-rich repeat LRR_6 PF13516.6 KKF94531.1 - 0.42 10.8 0.0 0.42 10.8 0.0 11.1 14 0 0 14 14 14 0 Leucine Rich repeat Glyco_transf_22 PF03901.17 KKF94532.1 - 1.7e-41 142.8 16.1 2.2e-41 142.4 16.1 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family UCH PF00443.29 KKF94533.1 - 5.3e-52 176.9 0.1 9.4e-52 176.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKF94533.1 - 1.2e-23 84.3 2.8 4.2e-18 66.0 0.5 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase hNIFK_binding PF12196.8 KKF94533.1 - 0.029 13.9 4.9 0.42 10.1 0.2 3.3 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Peptidase_C98 PF15499.6 KKF94533.1 - 0.18 11.3 4.7 0.73 9.2 1.4 2.9 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Tox-REase-3 PF15647.6 KKF94533.1 - 0.87 9.9 4.2 11 6.3 1.9 2.5 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 3 Mito_carr PF00153.27 KKF94534.1 - 2e-39 133.4 10.1 2.6e-17 62.5 0.3 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein NPP1 PF05630.11 KKF94535.1 - 2.1e-60 204.2 0.0 2.5e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) CC2D2AN-C2 PF15625.6 KKF94535.1 - 0.19 11.4 0.1 7.4 6.3 0.1 2.2 2 0 0 2 2 2 0 CC2D2A N-terminal C2 domain His_Phos_1 PF00300.22 KKF94536.1 - 0.21 11.3 0.0 0.46 10.1 0.0 1.6 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) CBS PF00571.28 KKF94537.1 - 1.6e-06 28.5 0.0 0.23 11.9 0.0 3.0 2 1 1 3 3 3 2 CBS domain DUF4349 PF14257.6 KKF94538.1 - 0.048 13.1 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Epimerase PF01370.21 KKF94539.1 - 3.1e-18 66.1 0.0 4.2e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKF94539.1 - 2.1e-06 27.4 0.0 2.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKF94539.1 - 4.7e-06 25.9 0.0 5.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KKF94539.1 - 0.00059 18.9 0.0 0.0011 18.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKF94539.1 - 0.1 12.1 0.0 1 8.8 0.0 2.3 3 0 0 3 3 3 0 short chain dehydrogenase KR PF08659.10 KKF94539.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 KR domain DUF3602 PF12223.8 KKF94540.1 - 8.6e-18 64.7 26.5 2.6e-10 40.8 4.8 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) SNF2_N PF00176.23 KKF94541.1 - 5.1e-51 173.4 0.1 9.5e-51 172.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKF94541.1 - 2.7e-15 56.6 0.1 9e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Alpha-2-MRAP_N PF06400.11 KKF94541.1 - 0.11 12.4 5.8 0.052 13.5 2.7 2.0 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain RPAP3_C PF13877.6 KKF94541.1 - 0.24 12.0 0.8 0.59 10.7 0.1 2.1 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 VMA21 PF09446.10 KKF94542.1 - 3.5e-15 55.8 8.1 5.1e-15 55.3 8.1 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.9 KKF94543.1 - 1.2e-25 89.9 0.2 1.2e-25 89.9 0.2 3.0 3 1 0 3 3 3 1 Uncharacterised protein (DUF2406) hNIFK_binding PF12196.8 KKF94543.1 - 0.19 11.3 0.1 0.44 10.1 0.1 1.6 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK SMC_N PF02463.19 KKF94544.1 - 4.7e-64 215.8 1.1 9.6e-64 214.8 1.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKF94544.1 - 1.6e-28 99.4 0.0 9.8e-28 96.8 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KKF94544.1 - 5.7e-19 69.4 0.0 5.7e-19 69.4 0.0 6.8 2 2 3 5 5 2 1 AAA domain AAA_15 PF13175.6 KKF94544.1 - 5.5e-16 59.2 40.5 4.1e-13 49.8 9.9 4.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KKF94544.1 - 2.5e-14 53.8 13.9 9.1e-09 35.5 0.2 4.4 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KKF94544.1 - 0.00046 20.4 0.1 0.002 18.3 0.1 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Tropomyosin PF00261.20 KKF94544.1 - 0.0063 15.9 15.6 0.0063 15.9 15.6 6.4 2 2 2 5 5 5 2 Tropomyosin Sec2p PF06428.11 KKF94544.1 - 0.0098 15.8 8.6 0.0098 15.8 8.6 8.3 5 3 2 8 8 8 1 GDP/GTP exchange factor Sec2p AAA_29 PF13555.6 KKF94544.1 - 0.018 14.8 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MtrB PF05440.12 KKF94544.1 - 0.093 13.2 0.1 21 5.6 0.0 3.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B ABC_tran PF00005.27 KKF94544.1 - 0.27 11.7 0.0 0.27 11.7 0.0 6.4 3 2 0 3 3 1 0 ABC transporter AAA_27 PF13514.6 KKF94544.1 - 0.52 9.9 0.0 0.15 11.6 2.3 6.6 6 2 1 7 7 7 0 AAA domain AAA_13 PF13166.6 KKF94544.1 - 3.6 6.1 92.8 0.13 10.9 11.0 5.5 5 1 1 6 6 6 0 AAA domain MRP-L46 PF11788.8 KKF94545.1 - 9e-29 100.6 0.1 1.7e-28 99.7 0.1 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX_4 PF14815.6 KKF94545.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain Ribosomal_L37ae PF01780.19 KKF94547.1 - 2e-40 136.8 6.6 2.2e-40 136.6 6.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KKF94547.1 - 0.016 15.2 2.6 0.027 14.5 2.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 KKF94547.1 - 0.023 15.1 0.7 8 7.1 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_13 PF17977.1 KKF94547.1 - 0.043 14.0 0.9 0.059 13.5 0.9 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rpr2 PF04032.16 KKF94547.1 - 0.064 13.5 2.6 1.3 9.3 2.6 2.3 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-Sec23_Sec24 PF04810.15 KKF94547.1 - 3 8.0 6.4 2.2 8.4 0.2 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Cpn60_TCP1 PF00118.24 KKF94548.1 - 1.2e-149 499.1 11.6 1.3e-149 498.9 11.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2204 PF09970.9 KKF94548.1 - 0.031 13.9 1.4 5.3 6.6 0.0 2.8 3 0 0 3 3 3 0 Nucleotidyl transferase of unknown function (DUF2204) PrpR_N PF06506.11 KKF94548.1 - 0.044 13.4 0.6 0.15 11.7 0.2 2.1 2 0 0 2 2 2 0 Propionate catabolism activator HMG_box PF00505.19 KKF94549.1 - 1.2e-05 25.7 1.0 2e-05 24.9 0.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box CCDC106 PF15794.5 KKF94549.1 - 0.051 13.3 0.0 0.051 13.3 0.0 2.1 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 106 LCD1 PF09798.9 KKF94549.1 - 0.19 10.2 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4407 PF14362.6 KKF94549.1 - 3.4 6.9 6.9 41 3.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF155 PF02582.14 KKF94550.1 - 4.8e-50 170.1 0.2 7e-50 169.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 KKF94550.1 - 0.025 15.0 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DEAD PF00270.29 KKF94551.1 - 1.4e-28 99.8 0.3 4.1e-28 98.3 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF94551.1 - 1.2e-18 67.4 0.0 6e-18 65.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF94551.1 - 1.7e-08 34.7 0.0 3.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TIP41 PF04176.13 KKF94552.1 - 3.8e-68 228.3 0.3 5.2e-68 227.9 0.3 1.2 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 KKF94554.1 - 9.1e-70 235.0 0.0 1e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF94554.1 - 9.5e-41 139.8 0.0 1.1e-40 139.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF94554.1 - 9.2e-07 28.4 0.0 2.3e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KKF94554.1 - 0.001 18.4 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KKF94554.1 - 0.026 14.1 0.0 0.047 13.3 0.0 1.4 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KKF94554.1 - 0.041 12.8 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KKF94554.1 - 0.08 12.5 0.0 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KKF94554.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL DnaJ PF00226.31 KKF94555.1 - 1.5e-12 47.5 1.0 3.4e-12 46.3 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain MKRN1_C PF15815.5 KKF94555.1 - 0.097 13.1 3.8 0.21 12.0 3.4 1.8 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal GREB1 PF15782.5 KKF94555.1 - 1.1 6.3 5.5 1.1 6.3 5.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DIOX_N PF14226.6 KKF94556.1 - 2.1e-24 86.5 0.0 3.4e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKF94556.1 - 7.3e-20 71.3 0.0 1.6e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PGAP1 PF07819.13 KKF94556.1 - 0.0039 16.9 0.6 0.0089 15.8 0.6 1.6 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KKF94556.1 - 0.069 12.4 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKF94556.1 - 0.13 12.8 8.7 0.4 11.3 8.6 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family PTPLA PF04387.14 KKF94557.1 - 8.2e-52 175.3 10.7 8.2e-52 175.3 10.7 1.6 2 1 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA GCV_T PF01571.21 KKF94558.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Epimerase PF01370.21 KKF94559.1 - 2.7e-13 50.0 0.4 4.4e-13 49.3 0.4 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKF94559.1 - 1.9e-08 34.1 0.1 1.4e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KKF94559.1 - 3.2e-08 33.7 1.1 4.5e-08 33.2 1.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KKF94559.1 - 9.9e-08 31.4 0.7 5.2e-07 29.1 0.7 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KKF94559.1 - 1e-07 31.7 0.1 0.0055 16.1 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKF94559.1 - 2.1e-07 30.2 0.1 1.3e-06 27.6 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKF94559.1 - 0.00085 18.8 0.2 0.0048 16.4 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_2 PF03446.15 KKF94559.1 - 0.036 14.2 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KKF94559.1 - 0.076 12.4 0.0 0.79 9.1 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KKF94560.1 - 3.4e-13 49.6 0.2 7.3e-13 48.5 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKF94560.1 - 9.9e-09 35.3 1.3 1.5e-08 34.8 1.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KKF94560.1 - 1e-08 35.0 0.0 0.0036 16.8 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKF94560.1 - 7.9e-08 31.7 1.0 1.2e-06 27.8 1.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KKF94560.1 - 1.1e-07 31.7 0.1 3.2e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 KKF94560.1 - 4.1e-06 26.0 0.2 1.4e-05 24.3 0.2 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKF94560.1 - 0.0012 18.4 0.6 0.005 16.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase DNA_pol_phi PF04931.13 KKF94561.1 - 3.1 5.8 14.6 4.5 5.2 14.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi DEAD PF00270.29 KKF94562.1 - 1.5e-41 142.1 0.0 4.7e-41 140.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF94562.1 - 8.1e-30 103.4 0.0 2e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF94562.1 - 7.2e-06 26.1 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Serglycin PF04360.12 KKF94562.1 - 0.035 14.1 0.1 0.072 13.0 0.1 1.6 1 0 0 1 1 1 0 Serglycin SWI2_SNF2 PF18766.1 KKF94562.1 - 0.053 13.2 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 SWI2/SNF2 ATPase FHA PF00498.26 KKF94563.1 - 3.4e-17 62.5 0.0 5.6e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KKF94563.1 - 9.2e-13 47.7 6.2 1.7e-12 46.9 6.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KKF94563.1 - 2.4e-06 27.8 9.4 4e-06 27.1 9.4 1.4 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 KKF94563.1 - 0.00039 20.7 0.0 0.00082 19.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-HC5HC2H PF13771.6 KKF94563.1 - 0.0066 16.7 1.8 0.013 15.7 1.8 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.6 KKF94563.1 - 0.0076 16.1 9.6 0.014 15.2 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKF94563.1 - 0.0082 16.0 8.6 0.014 15.3 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKF94563.1 - 0.022 14.6 5.1 0.036 13.9 5.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKF94563.1 - 0.026 14.5 6.5 0.044 13.8 6.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 KKF94563.1 - 0.028 14.5 1.9 0.053 13.6 1.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KKF94563.1 - 0.036 14.3 6.8 0.08 13.2 6.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KKF94563.1 - 0.073 13.1 9.0 0.14 12.2 9.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 KKF94563.1 - 0.087 12.7 4.7 0.19 11.7 4.7 1.6 1 0 0 1 1 1 0 PHD-finger lci PF12197.8 KKF94563.1 - 0.84 9.5 2.8 0.45 10.4 0.3 1.8 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein OrfB_Zn_ribbon PF07282.11 KKF94563.1 - 5.2 7.1 5.1 10 6.1 0.5 2.6 1 1 0 2 2 2 0 Putative transposase DNA-binding domain Peptidase_M16_C PF05193.21 KKF94564.1 - 2.8e-52 177.4 0.0 4.5e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKF94564.1 - 2.9e-40 137.6 0.0 1.1e-39 135.8 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF5473 PF17567.2 KKF94565.1 - 0.089 13.1 0.5 0.73 10.1 0.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5473) SMYLE_N PF18615.1 KKF94565.1 - 2.3 7.7 9.0 4.9 6.6 9.0 1.5 1 1 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain S1 PF00575.23 KKF94566.1 - 1.2e-72 240.2 22.7 2.7e-13 50.1 0.6 12.4 12 1 0 12 12 12 10 S1 RNA binding domain TPR_19 PF14559.6 KKF94566.1 - 3.1e-10 40.4 6.7 0.00011 22.6 0.3 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKF94566.1 - 1.5e-06 28.5 11.0 0.1 13.5 0.4 6.0 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKF94566.1 - 1.8e-06 28.5 3.6 0.012 16.2 1.4 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKF94566.1 - 9.2e-05 22.7 0.6 0.14 12.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKF94566.1 - 0.00019 21.4 0.0 1 9.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKF94566.1 - 0.0017 18.3 3.4 14 6.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KKF94566.1 - 0.0047 17.2 0.6 3.4 8.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 KKF94566.1 - 0.0053 16.7 14.2 4.5 7.3 0.1 6.8 8 0 0 8 8 8 2 RNase II-type exonuclease C-terminal S1 domain RuvA_N PF01330.21 KKF94566.1 - 0.023 14.8 0.0 0.082 13.0 0.0 2.0 1 0 0 1 1 1 0 RuvA N terminal domain SPOB_a PF14689.6 KKF94566.1 - 0.036 13.8 0.1 12 5.7 0.0 3.3 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_4 PF07721.14 KKF94566.1 - 0.04 14.5 1.1 7 7.6 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KKF94566.1 - 0.045 13.9 1.5 1.9 8.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KKF94566.1 - 0.053 13.4 2.2 25 4.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RXT2_N PF08595.11 KKF94566.1 - 4.6 7.3 13.8 4.2 7.4 0.5 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 KKF94566.1 - 5.8 6.2 29.1 0.63 9.3 14.3 2.3 2 0 0 2 2 2 0 NOA36 protein Vps16_N PF04841.13 KKF94567.1 - 1.3e-85 287.7 0.0 2.1e-85 286.9 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KKF94567.1 - 3.4e-71 239.9 0.0 5.9e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region DOT1 PF08123.13 KKF94568.1 - 1.6e-71 240.1 0.0 2.1e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 KKF94568.1 - 0.07 13.8 0.1 0.21 12.3 0.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain DUF3939 PF13075.6 KKF94568.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) MTS PF05175.14 KKF94568.1 - 0.095 12.2 0.1 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain MCM2_N PF12619.8 KKF94568.1 - 0.12 12.6 1.3 0.21 11.9 1.3 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 CMAS PF02353.20 KKF94568.1 - 0.15 11.3 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Imm3 PF14425.6 KKF94568.1 - 0.17 11.9 0.2 0.52 10.4 0.1 1.8 2 0 0 2 2 2 0 Immunity protein Imm3 PfkB PF00294.24 KKF94569.1 - 3.5e-57 194.0 2.7 4.9e-57 193.5 2.7 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KKF94569.1 - 7.1e-07 28.8 1.1 1.1e-06 28.3 1.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase MoCF_biosynth PF00994.24 KKF94569.1 - 0.033 13.8 0.5 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Probable molybdopterin binding domain AAA PF00004.29 KKF94570.1 - 4.4e-27 95.1 0.3 1.4e-26 93.5 0.3 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKF94570.1 - 1.9e-14 53.2 0.0 4e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KKF94570.1 - 9.6e-06 25.5 3.1 2.5e-05 24.1 3.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KKF94570.1 - 0.0075 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_OB_N PF17758.1 KKF94570.1 - 0.039 13.6 0.2 0.14 11.8 0.2 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Na_Ca_ex PF01699.24 KKF94571.1 - 1.1e-18 67.6 25.6 1.5e-13 50.9 8.4 3.8 5 0 0 5 5 5 2 Sodium/calcium exchanger protein FGGY_C PF02782.16 KKF94572.1 - 2e-67 226.8 3.5 4.3e-67 225.7 3.5 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKF94572.1 - 5.1e-64 216.2 0.0 7.3e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KKF94572.1 - 0.057 12.9 0.1 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Cytochrom_C PF00034.21 KKF94573.1 - 1.5e-10 42.1 0.1 2.3e-10 41.5 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KKF94573.1 - 1.7e-08 34.6 2.8 8.5e-08 32.4 2.8 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KKF94573.1 - 0.0014 18.4 2.4 0.02 14.6 2.4 2.3 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 KKF94573.1 - 0.08 13.6 0.0 0.088 13.4 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase AAA PF00004.29 KKF94574.1 - 3.3e-64 215.2 0.0 4.8e-44 150.0 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKF94574.1 - 3.5e-10 39.5 1.4 5.7e-06 26.0 0.0 3.0 3 0 0 3 3 3 2 AAA+ lid domain AAA_5 PF07728.14 KKF94574.1 - 3.2e-08 33.7 0.1 0.0005 20.1 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KKF94574.1 - 1.1e-07 32.0 0.0 0.00022 21.2 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_16 PF13191.6 KKF94574.1 - 2.6e-07 31.2 4.8 0.00073 20.0 0.0 4.7 3 2 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KKF94574.1 - 1.7e-06 28.3 3.5 0.018 15.3 0.0 5.4 4 2 1 6 6 5 1 AAA domain RNA_helicase PF00910.22 KKF94574.1 - 4.7e-05 23.7 0.0 0.044 14.2 0.0 3.2 2 1 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 KKF94574.1 - 0.00012 21.9 0.0 0.003 17.3 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KKF94574.1 - 0.00014 21.1 0.0 0.29 10.3 0.0 3.1 2 2 0 2 2 2 2 Protein of unknown function (DUF815) AAA_33 PF13671.6 KKF94574.1 - 0.00043 20.5 0.0 0.0018 18.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KKF94574.1 - 0.0006 20.0 0.0 0.017 15.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KKF94574.1 - 0.0016 19.0 0.0 0.66 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KKF94574.1 - 0.0016 17.9 0.3 0.12 11.7 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KKF94574.1 - 0.0019 17.5 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 KKF94574.1 - 0.0022 17.6 0.1 1.5 8.4 0.1 2.8 1 1 0 2 2 2 1 AAA domain TsaE PF02367.17 KKF94574.1 - 0.0027 17.7 0.0 3.4 7.7 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KKF94574.1 - 0.0031 17.4 0.4 0.59 9.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KKF94574.1 - 0.0037 17.2 0.7 1.4 8.8 0.0 3.9 3 1 1 4 4 4 1 NACHT domain AAA_7 PF12775.7 KKF94574.1 - 0.0049 16.4 0.0 0.89 9.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KKF94574.1 - 0.0093 15.3 0.2 0.17 11.2 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin ABC_tran PF00005.27 KKF94574.1 - 0.01 16.4 0.0 3.1 8.3 0.0 3.6 3 0 0 3 3 3 0 ABC transporter Sigma54_activ_2 PF14532.6 KKF94574.1 - 0.011 15.9 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KKF94574.1 - 0.017 14.9 0.0 0.069 12.9 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 KKF94574.1 - 0.035 14.1 0.0 0.7 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KKF94574.1 - 0.043 14.1 0.5 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KKF94574.1 - 0.044 14.1 1.5 5.9 7.2 0.1 3.3 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KKF94574.1 - 0.073 12.8 0.0 0.64 9.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain GREB1 PF15782.5 KKF94574.1 - 0.18 8.9 0.1 0.26 8.4 0.1 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ATPase PF06745.13 KKF94574.1 - 0.18 11.1 0.5 1.1 8.5 0.0 2.5 4 0 0 4 4 4 0 KaiC ProSAAS PF07259.12 KKF94574.1 - 0.25 11.3 3.8 0.49 10.3 3.8 1.4 1 0 0 1 1 1 0 ProSAAS precursor Snf7 PF03357.21 KKF94575.1 - 2.9e-37 127.9 1.3 3.2e-37 127.8 1.3 1.0 1 0 0 1 1 1 1 Snf7 Fructosamin_kin PF03881.14 KKF94576.1 - 2e-54 184.8 0.1 2.5e-54 184.4 0.1 1.2 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.11 KKF94576.1 - 0.025 13.4 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) CHZ PF09649.10 KKF94578.1 - 2.7e-19 68.3 3.3 2.7e-19 68.3 3.3 3.1 4 0 0 4 4 4 2 Histone chaperone domain CHZ Use1 PF09753.9 KKF94579.1 - 0.0077 16.0 0.0 0.0077 16.0 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Apc15p PF05841.11 KKF94580.1 - 4.4e-16 59.8 2.4 1.7e-15 57.9 0.1 2.4 2 0 0 2 2 2 1 Apc15p protein GATase_2 PF00310.21 KKF94581.1 - 2.2e-181 603.2 0.0 3e-181 602.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KKF94581.1 - 3.9e-157 523.1 0.0 5.9e-157 522.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KKF94581.1 - 7e-113 376.8 0.0 7.8e-111 370.0 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KKF94581.1 - 6.6e-85 283.5 5.9 1.1e-84 282.8 5.9 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KKF94581.1 - 7.1e-24 84.5 0.1 4.5e-23 81.9 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KKF94581.1 - 7.7e-22 77.2 0.1 1.6e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KKF94581.1 - 9.3e-09 35.4 0.0 3.2e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKF94581.1 - 1e-07 32.4 0.1 0.00015 22.2 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KKF94581.1 - 2.9e-06 26.8 0.0 5.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KKF94581.1 - 3e-06 27.1 0.1 0.00077 19.1 0.0 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKF94581.1 - 6.7e-05 21.8 0.5 0.00013 20.8 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KKF94581.1 - 0.00014 21.4 0.0 0.00033 20.1 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKF94581.1 - 0.00014 21.2 1.4 0.028 13.7 0.0 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKF94581.1 - 0.00073 18.8 0.0 0.0067 15.7 0.0 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KKF94581.1 - 0.0012 18.0 0.0 0.005 16.0 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.23 KKF94581.1 - 0.0032 17.4 0.0 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 KKF94581.1 - 0.0088 16.5 0.0 4.7 7.7 0.0 3.2 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KKF94581.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KKF94581.1 - 0.014 14.4 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KKF94581.1 - 0.028 13.7 0.0 4.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KKF94581.1 - 0.09 12.8 0.0 23 5.0 0.0 2.9 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase FMN_dh PF01070.18 KKF94581.1 - 0.09 11.8 0.5 0.32 10.0 0.5 1.9 1 0 0 1 1 1 0 FMN-dependent dehydrogenase F420_oxidored PF03807.17 KKF94581.1 - 0.097 13.3 0.0 1.5 9.4 0.0 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 KKF94581.1 - 0.1 12.6 0.0 0.47 10.4 0.0 2.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 KKF94581.1 - 0.13 11.3 0.5 0.62 9.1 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A FMO-like PF00743.19 KKF94581.1 - 0.2 10.1 0.0 23 3.2 0.0 2.9 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like DEAD PF00270.29 KKF94582.1 - 5.3e-31 107.7 0.0 1.7e-15 57.3 0.0 2.3 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF94582.1 - 3.8e-21 75.5 0.3 7.9e-21 74.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF94582.1 - 3.7e-05 23.8 0.0 0.00016 21.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SPX PF03105.19 KKF94582.1 - 0.0068 16.4 0.5 0.0068 16.4 0.5 3.2 2 1 0 2 2 2 1 SPX domain Bromodomain PF00439.25 KKF94583.1 - 3.8e-05 23.7 0.0 0.00014 21.9 0.0 1.8 1 1 0 1 1 1 1 Bromodomain SipA_VBS PF17985.1 KKF94584.1 - 0.13 12.2 0.3 4.3 7.4 0.1 2.6 2 0 0 2 2 2 0 SipA vinculin binding site Phage_TAC_10 PF10963.8 KKF94584.1 - 2.4 8.4 7.9 13 6.0 0.6 3.0 2 1 1 3 3 3 0 Phage tail assembly chaperone DUF16 PF01519.16 KKF94585.1 - 0.031 14.8 0.8 0.048 14.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 SKA1 PF07160.12 KKF94585.1 - 0.036 13.9 1.0 0.046 13.6 1.0 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF3450 PF11932.8 KKF94585.1 - 0.25 10.6 5.2 0.07 12.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Ecl1 PF12855.7 KKF94585.1 - 1.7 9.8 10.3 0.48 11.6 7.4 1.5 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins HSP70 PF00012.20 KKF94586.1 - 4.7e-58 196.8 23.7 7.4e-57 192.9 0.0 3.8 3 1 0 3 3 3 2 Hsp70 protein PIGA PF08288.12 KKF94587.1 - 4.2e-47 158.7 3.2 5.8e-47 158.2 0.6 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KKF94587.1 - 1.2e-29 103.5 0.3 1.9e-29 102.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KKF94587.1 - 2e-28 99.1 0.0 3.7e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKF94587.1 - 2e-24 86.5 0.1 4.8e-24 85.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KKF94587.1 - 1.1e-12 48.6 0.0 2.4e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KKF94587.1 - 5.8e-07 29.6 0.2 1.1e-06 28.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KKF94587.1 - 0.00028 21.2 0.0 0.0017 18.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KKF94587.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain ERAP1_C PF11838.8 KKF94588.1 - 9.2e-84 281.7 0.0 1.1e-82 278.1 0.0 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KKF94588.1 - 9.8e-81 270.5 2.0 1.4e-80 270.0 2.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KKF94588.1 - 9.9e-42 143.2 0.2 3.5e-41 141.4 0.1 2.0 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KKF94588.1 - 0.0034 17.4 0.1 0.25 11.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2808) Vps4_C PF09336.10 KKF94588.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain DUF45 PF01863.17 KKF94588.1 - 0.065 13.3 0.3 0.49 10.4 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF45 Y_phosphatase PF00102.27 KKF94589.1 - 1.1e-55 188.7 0.0 2.1e-51 174.8 0.0 3.1 2 1 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 KKF94589.1 - 0.0065 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KKF94589.1 - 0.014 15.4 0.2 0.071 13.1 0.1 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family FKBP_C PF00254.28 KKF94590.1 - 5.9e-32 109.9 0.0 9e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Presenilin PF01080.17 KKF94590.1 - 2.9 6.5 3.7 3.5 6.3 3.7 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 KKF94590.1 - 8.3 6.8 9.9 12 6.4 9.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPEL PF02755.15 KKF94591.1 - 8.9e-16 57.0 0.0 1.6e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 RPEL repeat Antimicrobial18 PF08130.11 KKF94591.1 - 0.041 14.0 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Type A lantibiotic family GDPD PF03009.17 KKF94592.1 - 2e-16 60.5 0.0 2.5e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Aldo_ket_red PF00248.21 KKF94592.1 - 0.00088 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_23 PF13489.6 KKF94593.1 - 9.2e-17 61.4 0.0 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF94593.1 - 8.9e-13 48.8 0.0 5e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF94593.1 - 8.9e-13 48.3 0.0 2.2e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF94593.1 - 7.3e-10 39.4 0.0 2.5e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF94593.1 - 2.4e-09 37.8 0.0 1e-08 35.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KKF94593.1 - 5.8e-06 26.5 0.0 1.3e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KKF94593.1 - 2.3e-05 23.9 0.0 0.00015 21.2 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KKF94593.1 - 0.0019 17.7 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KKF94593.1 - 0.054 13.1 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KKF94593.1 - 0.16 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Xan_ur_permease PF00860.20 KKF94594.1 - 1.6e-46 158.7 27.3 5.3e-37 127.4 14.1 2.1 1 1 1 2 2 2 2 Permease family WD40 PF00400.32 KKF94595.1 - 5.7e-06 27.0 2.8 20 6.3 0.0 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94595.1 - 1e-05 25.7 0.0 0.22 11.8 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Mpp10 PF04006.12 KKF94595.1 - 0.96 7.8 27.7 1.5 7.2 27.7 1.2 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 KKF94595.1 - 1.9 7.8 35.6 3.7 6.9 35.6 1.4 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 KKF94595.1 - 2.1 7.0 11.8 2.8 6.6 11.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 KKF94595.1 - 2.5 7.3 35.1 4.5 6.5 35.1 1.3 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 KKF94597.1 - 1.2e-55 187.8 0.8 1.2e-55 187.8 0.8 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KKF94597.1 - 7.1e-42 139.8 20.8 1.6e-09 37.7 0.0 8.2 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KKF94597.1 - 5.2e-21 74.8 1.9 4.3e-15 55.9 0.0 5.6 4 1 3 7 7 7 3 HEAT repeats HEAT PF02985.22 KKF94597.1 - 1.1e-07 31.5 0.0 0.14 12.5 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KKF94597.1 - 4.3e-06 27.1 2.3 0.00016 22.1 0.0 4.4 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 KKF94597.1 - 0.0026 17.8 1.0 0.46 10.5 0.0 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF1955 PF09205.10 KKF94597.1 - 0.044 13.5 0.1 0.32 10.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1955) Oxidored_molyb PF00174.19 KKF94598.1 - 1.2e-54 184.5 0.0 1.9e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KKF94598.1 - 7.6e-28 97.2 2.3 3e-25 88.8 2.3 2.4 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KKF94598.1 - 3.2e-13 49.6 0.1 7.1e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AMP-binding PF00501.28 KKF94599.1 - 5.7e-70 236.0 0.0 7.5e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKF94599.1 - 2.8e-09 37.8 0.1 6.1e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PIG-S PF10510.9 KKF94600.1 - 2.3e-123 412.8 0.3 2.2e-92 310.5 0.0 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein AhpC-TSA PF00578.21 KKF94602.1 - 2e-31 108.5 0.0 2.7e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKF94602.1 - 9.3e-13 48.1 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KKF94602.1 - 9e-10 38.2 0.0 2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin FMN_red PF03358.15 KKF94603.1 - 2.3e-11 43.7 0.0 3.1e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KKF94603.1 - 6.5e-07 29.3 0.0 8.2e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KKF94603.1 - 8e-05 22.9 0.7 0.00096 19.4 0.7 2.2 1 1 0 1 1 1 1 Flavodoxin Iso_dh PF00180.20 KKF94604.1 - 2.2e-96 323.0 0.0 3.1e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GTP_EFTU PF00009.27 KKF94605.1 - 1.6e-58 197.5 0.1 2.6e-58 196.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KKF94605.1 - 4.8e-33 113.5 0.0 9.1e-33 112.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KKF94605.1 - 2.4e-32 110.8 0.0 5.5e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KKF94605.1 - 4.4e-23 81.1 0.0 9.3e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKF94605.1 - 7.3e-12 45.5 0.0 1.6e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KKF94605.1 - 4.2e-06 26.6 0.0 9.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 KKF94605.1 - 0.03 14.8 0.0 0.51 10.9 0.0 2.3 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 KKF94605.1 - 0.05 13.7 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Cellulase PF00150.18 KKF94606.1 - 9.2e-50 169.6 0.1 1.3e-49 169.2 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KKF94606.1 - 2.5e-11 43.3 8.2 2.5e-11 43.3 8.2 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain CHASE4 PF05228.13 KKF94606.1 - 0.044 14.0 0.0 0.15 12.3 0.0 2.0 1 1 1 2 2 2 0 CHASE4 domain Nramp PF01566.18 KKF94607.1 - 1.5e-84 284.0 17.1 1.5e-84 284.0 17.1 2.2 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein GT87 PF09594.10 KKF94608.1 - 1.1 8.9 7.0 0.13 11.9 0.6 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 87 Shisa PF13908.6 KKF94608.1 - 1.5 9.1 0.0 1.5 9.1 0.0 3.9 3 2 2 5 5 5 0 Wnt and FGF inhibitory regulator SHS2_Rpb7-N PF03876.17 KKF94609.1 - 3.5e-16 59.3 0.0 7.2e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KKF94609.1 - 4e-10 39.9 0.0 6.3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 KKF94610.1 - 7e-15 54.9 0.0 1.2e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SipA_VBS PF17985.1 KKF94612.1 - 7.9 6.6 9.3 10 6.2 1.2 3.9 3 0 0 3 3 3 0 SipA vinculin binding site AAA_22 PF13401.6 KKF94614.1 - 1.4e-12 48.1 0.0 3.7e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKF94614.1 - 1.2e-08 35.5 0.1 6e-07 30.0 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KKF94614.1 - 4.6e-08 33.5 0.0 1.1e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 KKF94614.1 - 1e-06 28.6 0.1 5.5e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain TniB PF05621.11 KKF94614.1 - 0.0028 17.1 0.0 0.012 15.0 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 KKF94614.1 - 0.0042 17.5 0.0 0.0085 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KKF94614.1 - 0.0047 17.5 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 KKF94614.1 - 0.0052 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 KKF94614.1 - 0.0065 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KKF94614.1 - 0.0067 16.0 0.6 0.017 14.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKF94614.1 - 0.0071 16.1 0.0 0.023 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KKF94614.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 KKF94614.1 - 0.087 13.2 1.1 0.34 11.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 KKF94614.1 - 0.13 11.5 0.1 0.27 10.4 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 KKF94614.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KKF94614.1 - 0.17 11.2 0.0 0.39 10.0 0.0 1.5 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 KKF94614.1 - 0.2 11.6 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Pkinase PF00069.25 KKF94615.1 - 1.7e-59 201.3 0.0 5e-59 199.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF94615.1 - 1.3e-27 96.7 0.0 2.8e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKF94615.1 - 0.0046 16.3 0.1 0.0092 15.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KKF94615.1 - 0.017 14.7 0.2 0.099 12.3 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KKF94615.1 - 0.018 14.6 0.1 0.018 14.6 0.1 1.9 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KKF94615.1 - 0.043 12.6 0.0 0.083 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Yop-YscD_cpl PF16697.5 KKF94615.1 - 0.049 13.9 0.0 0.24 11.7 0.0 2.1 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain PH PF00169.29 KKF94617.1 - 1.4e-07 31.9 0.0 2.3e-06 28.1 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KKF94617.1 - 0.019 15.3 0.0 0.053 13.9 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain SpoIIE PF07228.12 KKF94618.1 - 0.00018 21.5 0.0 0.00037 20.5 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KKF94618.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 Protein phosphatase 2C PP2C PF00481.21 KKF94618.1 - 0.2 11.3 0.1 6.4 6.3 0.2 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C Fcf1 PF04900.12 KKF94619.1 - 2.3e-26 92.1 0.0 4.3e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.14 KKF94619.1 - 0.0077 14.6 7.4 0.011 14.1 7.4 1.2 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 KKF94619.1 - 2.3 8.3 24.9 1.4 8.9 23.1 1.4 1 1 0 1 1 1 0 YL1 nuclear protein SOBP PF15279.6 KKF94619.1 - 6.8 7.2 8.3 11 6.5 8.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF836 PF05768.14 KKF94620.1 - 3.8e-13 49.7 0.0 4.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KKF94620.1 - 0.00044 20.4 0.1 0.001 19.3 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 KKF94620.1 - 0.013 15.3 0.9 0.043 13.6 0.0 1.9 1 1 0 2 2 2 0 F plasmid transfer operon protein Nsp1 PF11501.8 KKF94620.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Non structural protein Nsp1 Arrestin_C PF02752.22 KKF94621.1 - 7.7e-09 36.1 0.0 2.3e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KKF94621.1 - 5.9e-08 32.9 0.0 3.7e-07 30.3 0.0 2.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Nop PF01798.18 KKF94622.1 - 2.5e-79 266.0 0.0 4.9e-79 265.0 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KKF94622.1 - 8.4e-15 54.9 0.1 3.8e-14 52.8 0.1 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 KKF94622.1 - 1.1 9.3 24.8 2.6 8.1 24.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Glyco_hydro_18 PF00704.28 KKF94623.1 - 1.1e-86 291.4 3.7 1.3e-86 291.2 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ABC_transp_aux PF09822.9 KKF94623.1 - 0.17 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system ubiquitin PF00240.23 KKF94624.1 - 3.8e-34 116.3 0.6 7.8e-34 115.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KKF94624.1 - 1.5e-26 92.3 1.6 1.5e-26 92.3 1.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KKF94624.1 - 2.4e-16 59.3 0.7 4.8e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KKF94624.1 - 2.4e-05 24.7 0.5 0.00013 22.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KKF94624.1 - 0.0012 18.9 0.7 0.0026 17.8 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KKF94624.1 - 0.0047 17.3 0.9 0.0078 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KKF94624.1 - 0.0054 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KKF94624.1 - 0.011 16.3 0.6 0.015 15.8 0.6 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KKF94624.1 - 0.019 15.0 1.0 5.8 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_S26e PF01283.19 KKF94625.1 - 1.7e-52 176.4 8.2 2e-52 176.2 8.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KKF94625.1 - 0.019 14.9 0.4 0.054 13.5 0.0 1.9 2 0 0 2 2 2 0 Zinc binding domain DUF1918 PF08940.11 KKF94625.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF4668 PF15701.5 KKF94625.1 - 0.24 11.2 2.2 0.22 11.3 1.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) p450 PF00067.22 KKF94626.1 - 1.1e-23 83.7 0.0 1.1e-23 83.7 0.0 2.1 3 0 0 3 3 3 1 Cytochrome P450 DnaJ PF00226.31 KKF94626.1 - 0.011 15.8 0.0 0.039 14.1 0.0 2.0 1 0 0 1 1 1 0 DnaJ domain MPDZ_u10 PF16667.5 KKF94626.1 - 2.8 8.9 5.0 2.1 9.3 1.8 2.4 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein Frag1 PF10277.9 KKF94627.1 - 7e-37 127.1 5.3 7e-37 127.1 5.3 3.0 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KKF94627.1 - 0.0088 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family U3_assoc_6 PF08640.11 KKF94628.1 - 1.6e-26 92.1 0.3 3.7e-26 91.0 0.3 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 KKF94628.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KKF94628.1 - 0.29 12.1 3.9 12 7.0 0.1 4.5 5 1 1 6 6 6 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 KKF94630.1 - 3.7e-22 78.6 1.4 7.3e-22 77.6 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKF94630.1 - 2.2e-07 30.9 0.7 4.2e-07 30.0 0.7 1.5 1 0 0 1 1 1 1 Berberine and berberine like Clathrin PF00637.20 KKF94631.1 - 8.9e-18 64.5 0.2 2.1e-17 63.3 0.2 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS NBP1 PF08537.10 KKF94631.1 - 0.013 14.9 0.1 0.03 13.8 0.1 1.5 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Vps39_1 PF10366.9 KKF94631.1 - 0.059 13.7 0.1 0.2 11.9 0.1 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Pox_Ag35 PF03286.14 KKF94631.1 - 0.21 11.4 10.2 0.84 9.4 9.6 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Mpp10 PF04006.12 KKF94631.1 - 0.27 9.6 14.2 0.48 8.8 14.2 1.3 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 KKF94631.1 - 0.28 9.4 11.7 0.53 8.5 11.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KKF94631.1 - 1.5 6.9 20.3 2.4 6.3 20.3 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KKF94631.1 - 2.3 7.5 21.7 5.7 6.3 21.7 1.5 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 KKF94631.1 - 4.7 6.3 10.0 8.5 5.5 10.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 KKF94631.1 - 4.8 7.6 5.4 17 5.9 5.0 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4746 PF15928.5 KKF94631.1 - 9.9 5.5 8.9 20 4.5 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PC_rep PF01851.22 KKF94632.1 - 0.0051 17.2 6.1 0.077 13.5 0.0 4.3 3 0 0 3 3 3 2 Proteasome/cyclosome repeat eIF3_N PF09440.10 KKF94633.1 - 4.5e-40 137.2 5.2 1.8e-39 135.2 3.7 2.7 3 1 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KKF94633.1 - 5.3e-12 46.2 0.0 1.7e-11 44.5 0.0 2.0 1 0 0 1 1 1 1 PCI domain DUF2532 PF10811.8 KKF94633.1 - 0.00096 19.2 0.1 0.0032 17.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2532) RPN7 PF10602.9 KKF94633.1 - 0.04 13.6 0.5 0.13 11.9 0.0 2.1 2 1 0 2 2 2 0 26S proteasome subunit RPN7 Img2 PF05046.14 KKF94634.1 - 8.9e-23 80.4 0.0 1.2e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) COX_ARM PF06481.14 KKF94634.1 - 0.086 12.8 0.6 0.28 11.1 0.1 1.9 2 0 0 2 2 2 0 COX Aromatic Rich Motif ARID PF01388.21 KKF94635.1 - 6.4e-17 62.0 0.3 1.4e-16 60.9 0.0 1.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain CUE PF02845.16 KKF94636.1 - 5.1e-07 29.3 0.0 1.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 CUE domain An_peroxidase PF03098.15 KKF94638.1 - 2e-45 155.4 0.0 3.6e-27 95.1 0.0 3.3 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 KKF94638.1 - 5.8e-07 28.6 0.0 2e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 RrnaAD PF00398.20 KKF94639.1 - 1.9e-08 33.7 0.0 3.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF2520 PF10728.9 KKF94639.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Glyco_transf_90 PF05686.12 KKF94640.1 - 1.7e-15 56.9 1.4 1.8e-11 43.6 0.1 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 90 Arginase PF00491.21 KKF94641.1 - 9.6e-76 254.9 0.4 1.1e-75 254.7 0.4 1.0 1 0 0 1 1 1 1 Arginase family DUF1993 PF09351.10 KKF94642.1 - 1.3e-36 126.2 0.0 1.4e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Glyco_hydro_18 PF00704.28 KKF94643.1 - 1.6e-66 225.2 0.0 1.7e-55 189.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKF94643.1 - 7.2e-40 135.2 141.8 1.7e-08 34.8 21.7 5.6 5 0 0 5 5 5 5 Chitin recognition protein Uds1 PF15456.6 KKF94644.1 - 2.2e-38 131.3 7.2 2.2e-38 131.3 7.2 6.6 4 2 1 6 6 6 1 Up-regulated During Septation ZapB PF06005.12 KKF94644.1 - 0.016 15.6 0.5 0.016 15.6 0.5 9.4 8 2 1 9 9 9 0 Cell division protein ZapB XhlA PF10779.9 KKF94644.1 - 0.053 13.7 0.2 0.053 13.7 0.2 7.9 9 0 0 9 9 9 0 Haemolysin XhlA RHH_8 PF17723.1 KKF94644.1 - 4.1 7.6 8.3 6 7.1 0.9 3.7 3 0 0 3 3 3 0 Ribbon-Helix-Helix transcriptional regulator family Cu-oxidase_3 PF07732.15 KKF94645.1 - 1.3e-39 134.8 0.9 4e-39 133.3 0.9 1.9 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKF94645.1 - 2.9e-30 104.8 11.3 3.6e-24 85.1 2.8 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKF94645.1 - 3.1e-14 53.4 0.0 6.1e-11 42.7 0.0 3.2 2 1 0 2 2 2 2 Multicopper oxidase V_ATPase_I PF01496.19 KKF94646.1 - 0 1054.0 0.0 0 1053.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 KKF94646.1 - 0.19 11.6 4.0 0.72 9.7 0.3 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Filament PF00038.21 KKF94646.1 - 2.3 7.7 9.5 2.3 7.7 2.5 2.4 2 1 0 2 2 2 0 Intermediate filament protein DHR10 PF18595.1 KKF94646.1 - 6.1 6.9 7.9 2.9 8.0 2.3 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain LRR_6 PF13516.6 KKF94647.1 - 0.00052 19.8 0.1 1.5 9.1 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat ING PF12998.7 KKF94648.1 - 5.9e-07 30.0 7.7 0.00067 20.2 0.0 3.1 3 0 0 3 3 3 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KKF94648.1 - 9.6e-07 28.6 7.2 1.8e-06 27.7 7.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KKF94648.1 - 0.025 14.8 3.3 0.079 13.2 3.3 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KKF94648.1 - 0.16 12.2 2.3 0.44 10.7 2.3 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain YabA PF06156.13 KKF94648.1 - 6.9 7.4 7.1 1.1e+02 3.5 7.1 2.6 1 1 0 1 1 1 0 Initiation control protein YabA DUF2052 PF09747.9 KKF94648.1 - 8 6.5 15.6 5.4 7.1 10.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Prenyltransf PF01255.19 KKF94649.1 - 3.4e-76 255.7 0.0 9.8e-76 254.2 0.0 1.6 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Gag_p12 PF01141.18 KKF94649.1 - 0.023 15.0 2.2 0.043 14.1 2.2 1.4 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 DUF1751 PF08551.10 KKF94650.1 - 3.8e-06 27.4 2.3 4.1e-06 27.3 0.3 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KKF94650.1 - 9.1e-05 22.5 7.1 9.1e-05 22.5 7.1 1.8 2 1 0 2 2 2 1 Rhomboid family SOCS PF12610.8 KKF94650.1 - 0.032 14.6 1.0 0.074 13.5 1.0 1.5 1 0 0 1 1 1 0 Suppressor of cytokine signalling XRN_M PF17846.1 KKF94652.1 - 2.7e-121 405.6 4.5 5.2e-87 292.6 0.3 2.5 2 1 1 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 KKF94652.1 - 8.4e-98 326.6 0.0 1.3e-97 326.0 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_2 PF13696.6 KKF94652.1 - 0.045 13.6 2.2 0.11 12.3 2.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KKF94652.1 - 0.25 11.5 2.9 0.49 10.6 2.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_25 PF13649.6 KKF94653.1 - 5.9e-12 46.1 4.0 8.5e-12 45.6 0.0 3.4 4 1 0 4 4 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF94653.1 - 3.4e-11 43.6 0.1 6.1e-10 39.6 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 KKF94653.1 - 6.1e-11 42.3 0.1 6.1e-11 42.3 0.1 2.8 2 1 0 2 2 1 1 Ribosomal protein L11 methyltransferase (PrmA) Uso1_p115_C PF04871.13 KKF94653.1 - 6.8e-11 42.6 21.8 6.8e-11 42.6 21.8 4.3 2 1 3 5 5 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Methyltransf_31 PF13847.6 KKF94653.1 - 1e-08 35.1 0.0 1e-08 35.1 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KKF94653.1 - 1.6e-06 27.8 0.0 6e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KKF94653.1 - 2.4e-06 27.5 0.1 2.4e-06 27.5 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF94653.1 - 8.9e-06 25.6 0.0 2.4e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF94653.1 - 9.5e-06 26.3 1.1 0.00013 22.7 0.0 3.3 3 0 0 3 3 2 1 Methyltransferase domain TehB PF03848.14 KKF94653.1 - 0.00079 18.9 0.1 0.003 17.0 0.1 2.0 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 KKF94653.1 - 0.0034 16.4 0.0 0.0034 16.4 0.0 2.4 2 1 0 3 3 3 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 KKF94653.1 - 0.0063 16.3 0.1 0.018 14.8 0.1 1.8 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 KKF94653.1 - 0.011 15.5 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Filament PF00038.21 KKF94653.1 - 0.014 15.0 46.4 0.018 14.6 44.8 1.9 2 0 0 2 2 2 0 Intermediate filament protein PCMT PF01135.19 KKF94653.1 - 0.025 14.4 0.1 0.058 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KKF94653.1 - 0.081 13.9 4.8 0.11 13.6 0.0 3.3 2 1 0 2 2 1 0 Methyltransferase domain PspA_IM30 PF04012.12 KKF94653.1 - 0.18 11.4 48.8 0.011 15.3 23.2 3.3 2 1 1 3 3 2 0 PspA/IM30 family DUF3584 PF12128.8 KKF94653.1 - 0.2 9.1 41.5 0.45 8.0 41.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0020 PF01170.18 KKF94653.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 FAM184 PF15665.5 KKF94653.1 - 0.85 9.4 53.3 0.11 12.2 12.0 2.6 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B ATG16 PF08614.11 KKF94653.1 - 0.87 9.8 50.9 2.2 8.4 28.1 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Rab5-bind PF09311.11 KKF94653.1 - 3.3 7.0 47.9 6.6 6.0 45.5 2.4 2 1 0 2 2 2 0 Rabaptin-like protein SF-assemblin PF06705.11 KKF94653.1 - 4.4 6.6 38.0 13 5.1 37.8 1.8 1 1 0 1 1 1 0 SF-assemblin/beta giardin Sec20 PF03908.13 KKF94653.1 - 4.9 7.1 7.0 10 6.1 4.9 2.7 1 1 1 2 2 2 0 Sec20 Rav1p_C PF12234.8 KKF94654.1 - 9.6e-209 694.9 0.2 9.8e-184 612.3 0.9 2.1 1 1 1 2 2 2 2 RAVE protein 1 C terminal Las1 PF04031.13 KKF94656.1 - 1.7e-60 203.6 5.3 3.1e-60 202.7 1.0 2.0 2 0 0 2 2 2 2 Las1-like SH3BGR PF04908.15 KKF94657.1 - 0.00061 19.9 0.1 0.0045 17.1 0.0 2.7 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein AAA PF00004.29 KKF94658.1 - 2e-49 167.4 0.0 4.1e-43 147.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKF94658.1 - 1.6e-05 24.6 2.4 0.034 14.0 0.0 3.4 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KKF94658.1 - 1.9e-05 25.1 0.7 0.015 15.7 0.0 3.7 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KKF94658.1 - 0.00015 21.6 0.0 0.00052 19.8 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 KKF94658.1 - 0.0012 18.0 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 KKF94658.1 - 0.0018 17.7 0.1 0.055 12.8 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KKF94658.1 - 0.0033 17.5 0.0 0.0083 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KKF94658.1 - 0.0071 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KKF94658.1 - 0.0074 15.9 0.1 0.044 13.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKF94658.1 - 0.0077 16.5 0.0 0.034 14.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KKF94658.1 - 0.0095 15.9 0.2 0.13 12.3 0.0 3.0 3 2 1 4 4 4 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KKF94658.1 - 0.011 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KKF94658.1 - 0.013 15.8 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 KKF94658.1 - 0.019 14.4 0.1 0.073 12.4 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 KKF94658.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KKF94658.1 - 0.092 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKF94658.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKF94658.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KKF94658.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 KKF94658.1 - 0.12 12.5 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KKF94658.1 - 0.16 12.4 0.1 0.54 10.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain Abhydro_lipase PF04083.16 KKF94659.1 - 4.6e-20 71.0 0.0 8e-20 70.2 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KKF94659.1 - 3.9e-07 30.0 1.2 1.6e-06 28.0 0.5 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKF94659.1 - 0.0013 18.0 0.1 0.0026 17.1 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 GTA_holin_3TM PF11351.8 KKF94659.1 - 3.3 8.3 10.2 0.15 12.6 1.5 2.3 1 1 1 2 2 2 0 Holin of 3TMs, for gene-transfer release Pkinase PF00069.25 KKF94660.1 - 5.7e-65 219.3 0.0 2.7e-64 217.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF94660.1 - 1.7e-36 125.9 0.0 1.5e-35 122.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF94660.1 - 0.0005 19.5 0.2 0.0023 17.3 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KKF94660.1 - 0.0022 18.0 0.1 0.0073 16.3 0.1 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KKF94660.1 - 0.023 13.8 0.1 0.046 12.8 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 AAA_8 PF12780.7 KKF94660.1 - 0.23 10.8 0.0 0.23 10.8 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region D4 DUF4695 PF15766.5 KKF94660.1 - 0.52 10.6 2.8 1.3 9.3 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) Syja_N PF02383.18 KKF94661.1 - 1.5e-76 257.8 0.0 2.5e-76 257.0 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KKF94661.1 - 7.6e-10 38.7 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Caskin-Pro-rich PF16907.5 KKF94661.1 - 0.22 12.1 9.5 0.57 10.7 9.5 1.7 1 0 0 1 1 1 0 Proline rich region of Caskin proteins Med3 PF11593.8 KKF94662.1 - 5.9 6.0 15.7 8 5.5 15.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal 14-3-3 PF00244.20 KKF94663.1 - 7.9e-107 355.8 0.4 9.6e-107 355.5 0.4 1.1 1 0 0 1 1 1 1 14-3-3 protein Ribosomal_60s PF00428.19 KKF94663.1 - 0.87 10.2 13.7 0.31 11.7 6.5 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_L36e PF01158.18 KKF94664.1 - 4.5e-41 139.0 6.5 5.1e-41 138.8 6.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 KKF94664.1 - 0.036 14.2 2.1 0.034 14.3 1.3 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 PBS_linker_poly PF00427.21 KKF94664.1 - 0.069 13.2 0.2 0.08 13.0 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide TUG-UBL1 PF11470.8 KKF94665.1 - 6.5e-26 90.3 0.3 2e-25 88.8 0.3 1.9 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KKF94665.1 - 0.003 17.6 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain Rad60-SLD PF11976.8 KKF94665.1 - 0.035 13.9 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2570 PF10828.8 KKF94665.1 - 0.13 12.1 0.4 0.33 10.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Proteasome PF00227.26 KKF94666.1 - 4.9e-36 124.0 0.0 5.5e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.20 KKF94667.1 - 2.5e-50 170.5 0.9 2.5e-50 170.5 0.9 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKF94667.1 - 1.8e-48 164.6 5.0 1.8e-48 164.6 5.0 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KKF94667.1 - 4.3e-23 82.7 1.1 1.4e-21 77.8 1.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKF94667.1 - 2.4e-21 75.6 0.0 4.3e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KKF94667.1 - 6.5e-18 64.2 0.0 1.6e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKF94667.1 - 1.5e-07 31.4 0.8 8.8e-06 25.6 0.9 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKF94667.1 - 0.00033 21.1 0.0 0.0013 19.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RhoGEF PF00621.20 KKF94668.1 - 8.6e-15 55.4 0.0 1.3e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain SBDS PF01172.18 KKF94669.1 - 2.3e-21 75.7 0.0 2.8e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein OPA3 PF07047.12 KKF94671.1 - 2.1e-44 150.3 0.1 3e-44 149.8 0.1 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) SR-25 PF10500.9 KKF94671.1 - 4.5 6.8 14.4 0.18 11.4 5.8 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NACHT PF05729.12 KKF94672.1 - 3e-18 66.3 0.0 4.5e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KKF94672.1 - 0.0036 17.7 0.0 0.0073 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KKF94672.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain DUF2075 PF09848.9 KKF94672.1 - 0.031 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KKF94672.1 - 0.042 14.2 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain PLAC8 PF04749.17 KKF94673.1 - 4e-24 85.5 16.4 4.9e-24 85.2 16.4 1.1 1 0 0 1 1 1 1 PLAC8 family Acetyltransf_1 PF00583.25 KKF94674.1 - 6.7e-09 36.0 0.0 1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKF94674.1 - 0.003 17.9 0.0 0.0047 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKF94674.1 - 0.0058 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KKF94674.1 - 0.024 14.6 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PALP PF00291.25 KKF94675.1 - 1.1e-75 254.9 0.7 1.4e-75 254.4 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KKF94675.1 - 8.2e-40 134.5 0.0 1.2e-18 66.6 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.13 KKF94676.1 - 1.5e-22 79.5 0.4 2.7e-22 78.7 0.4 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region TLD PF07534.16 KKF94677.1 - 4.7e-28 98.1 0.1 8.5e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 KKF94677.1 - 1.7e-07 32.2 0.0 4.7e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function Nucleoporin_FG PF13634.6 KKF94678.1 - 2.6e-13 50.6 72.6 6.4e-07 30.1 14.9 10.2 4 2 5 9 9 9 5 Nucleoporin FG repeat region Ran_BP1 PF00638.18 KKF94678.1 - 3.9e-13 49.7 0.0 8.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain PIG-Y PF15159.6 KKF94680.1 - 1.7e-22 80.1 7.7 2.8e-22 79.4 7.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 KKF94680.1 - 0.31 11.6 2.5 2.7 8.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) SOG2 PF10428.9 KKF94680.1 - 8.1 5.5 19.1 14 4.7 19.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4131 PF13567.6 KKF94681.1 - 0.16 11.6 0.7 0.2 11.3 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SUR7 PF06687.12 KKF94681.1 - 1.1 8.9 5.0 26 4.3 4.5 2.1 2 0 0 2 2 2 0 SUR7/PalI family Dynamin_N PF00350.23 KKF94682.1 - 8.5e-45 152.8 0.0 1.5e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KKF94682.1 - 4.7e-11 42.4 0.1 5.4e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KKF94682.1 - 1.8e-05 24.8 0.0 6.3e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKF94682.1 - 0.028 14.8 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KKF94682.1 - 0.031 14.5 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KKF94682.1 - 0.043 13.6 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KKF94682.1 - 0.14 12.4 0.0 0.64 10.2 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2201_N PF13203.6 KKF94682.1 - 0.14 11.7 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain AAA_15 PF13175.6 KKF94682.1 - 0.18 11.5 1.5 0.27 10.9 0.3 1.8 2 0 0 2 2 2 0 AAA ATPase domain GATase_4 PF13230.6 KKF94683.1 - 1.3e-16 60.3 0.0 2.9e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 KKF94683.1 - 3.1e-09 37.1 0.0 5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain HSP90 PF00183.18 KKF94683.1 - 0.2 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Hsp90 protein PQ-loop PF04193.14 KKF94685.1 - 6.4e-17 61.1 0.4 6.4e-17 61.1 0.4 1.9 2 0 0 2 2 2 1 PQ loop repeat Mito_carr PF00153.27 KKF94686.1 - 8.3e-72 237.2 0.2 1.3e-24 85.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KKF94686.1 - 6.1e-15 55.4 0.7 3e-06 27.6 0.1 3.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KKF94686.1 - 2e-13 49.1 0.0 0.002 17.9 0.0 5.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KKF94686.1 - 4.8e-13 47.6 0.0 0.0013 18.1 0.0 4.8 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KKF94686.1 - 5.9e-09 35.6 0.0 0.058 13.3 0.0 4.7 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 KKF94686.1 - 0.0024 17.3 0.1 1.2 8.8 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 KKF94686.1 - 0.012 15.9 0.0 5.3 7.4 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain FbpA PF05833.11 KKF94686.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Cyclin_N PF00134.23 KKF94687.1 - 2.7e-42 143.5 0.1 7.3e-42 142.1 0.1 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKF94687.1 - 6e-33 113.5 0.1 1.6e-32 112.1 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Latexin PF06907.12 KKF94687.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Latexin TUSC2 PF15000.6 KKF94687.1 - 0.058 13.7 0.8 0.18 12.1 0.8 1.8 1 0 0 1 1 1 0 Tumour suppressor candidate 2 5_nucleotid_C PF02872.18 KKF94688.1 - 8.3e-31 107.3 0.5 1.7e-30 106.3 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KKF94688.1 - 6e-11 43.2 0.3 9.4e-11 42.6 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.6 KKF94688.1 - 0.00071 19.0 0.1 0.0016 17.8 0.1 1.5 1 0 0 1 1 1 1 YmdB-like protein Serglycin PF04360.12 KKF94688.1 - 3.2 7.7 8.7 8.7 6.3 8.7 1.7 1 0 0 1 1 1 0 Serglycin 5_nucleotid_C PF02872.18 KKF94689.1 - 1.2e-32 113.3 0.0 2.6e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KKF94689.1 - 3e-11 44.2 0.4 4.8e-11 43.5 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.6 KKF94689.1 - 9.2e-05 21.9 0.2 0.00018 20.9 0.2 1.4 1 0 0 1 1 1 1 YmdB-like protein YL1 PF05764.13 KKF94689.1 - 0.003 17.7 0.6 0.003 17.7 0.6 5.3 4 1 1 5 5 5 1 YL1 nuclear protein 4HBT PF03061.22 KKF94690.1 - 2.4e-11 43.8 0.1 4.6e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KKF94690.1 - 0.029 14.5 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) CFEM PF05730.11 KKF94691.1 - 2.2e-06 27.6 13.8 2.9e-06 27.3 13.8 1.2 1 0 0 1 1 1 1 CFEM domain MMR_HSR1 PF01926.23 KKF94692.1 - 2.4e-12 47.0 0.0 6.7e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKF94692.1 - 3.7e-05 23.3 0.2 7.9e-05 22.2 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKF94692.1 - 0.00026 20.9 0.2 0.002 18.0 0.2 2.5 1 1 0 1 1 1 1 RsgA GTPase MeaB PF03308.16 KKF94692.1 - 0.0014 17.7 0.2 0.0034 16.4 0.3 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB IIGP PF05049.13 KKF94692.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 KKF94692.1 - 0.02 15.0 3.3 0.2 11.7 0.3 2.6 3 0 0 3 3 3 0 Dynamin family AAA_16 PF13191.6 KKF94692.1 - 0.054 13.9 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AIG1 PF04548.16 KKF94692.1 - 0.058 12.7 0.4 0.92 8.8 0.2 2.6 2 1 0 2 2 2 0 AIG1 family Arm-DNA-bind_3 PF13356.6 KKF94692.1 - 0.07 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain PHD PF00628.29 KKF94693.1 - 5.2e-10 39.1 2.5 1.2e-09 37.9 2.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKF94693.1 - 0.0029 17.1 5.9 0.0053 16.3 5.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 KKF94693.1 - 0.05 13.6 2.2 0.12 12.4 2.2 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger Presenilin PF01080.17 KKF94694.1 - 0.17 10.6 0.5 0.25 10.1 0.5 1.2 1 0 0 1 1 1 0 Presenilin Sugar_tr PF00083.24 KKF94695.1 - 6.5e-20 71.4 11.2 2.4e-10 39.9 1.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKF94695.1 - 1.1e-18 67.2 30.1 1.4e-11 43.9 8.6 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKF94695.1 - 0.001 17.7 1.2 0.001 17.7 1.2 2.3 2 1 1 3 3 3 1 MFS/sugar transport protein LacY_symp PF01306.19 KKF94695.1 - 0.13 11.0 4.9 0.033 12.9 1.5 1.7 2 0 0 2 2 2 0 LacY proton/sugar symporter RRM_1 PF00076.22 KKF94696.1 - 1.6e-15 56.6 0.0 2.6e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKF94696.1 - 0.034 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KKF94696.1 - 0.059 13.4 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif ER_lumen_recept PF00810.18 KKF94697.1 - 2.1e-20 74.0 0.7 2.1e-20 74.0 0.7 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor LicD PF04991.13 KKF94698.1 - 4.1e-12 46.7 0.7 2.3e-06 27.9 0.1 2.4 2 1 0 3 3 3 2 LicD family DUF829 PF05705.14 KKF94699.1 - 4.3e-48 164.3 0.0 5.1e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) TPR_MLP1_2 PF07926.12 KKF94700.1 - 0.034 14.2 8.9 0.13 12.3 8.9 2.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KKF94700.1 - 2.4 8.7 8.0 0.97 10.0 3.3 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region CHCH PF06747.13 KKF94701.1 - 0.34 11.1 3.2 0.85 9.8 3.2 1.7 1 1 0 1 1 1 0 CHCH domain Ribosomal_S17_N PF16205.5 KKF94702.1 - 4.1e-33 113.6 0.4 6.5e-33 112.9 0.4 1.3 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KKF94702.1 - 3.6e-26 91.1 0.2 7.1e-26 90.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.6 KKF94703.1 - 9.5e-126 421.3 84.0 7.3e-83 279.4 67.2 5.0 1 1 2 3 3 3 3 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KKF94703.1 - 1.4e-113 378.9 5.6 1.4e-113 378.9 5.6 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KKF94703.1 - 1.6e-05 24.9 0.0 5.1e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Spc7_C2 COG2 PF06148.11 KKF94703.1 - 0.04 14.0 0.5 0.14 12.2 0.5 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Csm1_N PF18504.1 KKF94703.1 - 2.5 8.5 6.3 7.2 7.0 1.8 3.6 3 0 0 3 3 3 0 Csm1 N-terminal domain Phage_TAC_4 PF08748.11 KKF94703.1 - 5.8 7.3 10.1 0.24 11.7 3.0 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone Atg14 PF10186.9 KKF94704.1 - 1.6e-52 178.6 0.0 2.2e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 KKF94704.1 - 0.16 12.0 1.2 0.27 11.3 1.2 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3807 PF12720.7 KKF94705.1 - 8.2e-28 97.9 0.4 8.2e-28 97.9 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3807) RE_NgoFVII PF09565.10 KKF94705.1 - 0.12 11.6 2.2 0.1 11.9 0.4 1.7 2 0 0 2 2 2 0 NgoFVII restriction endonuclease Pkinase PF00069.25 KKF94706.1 - 7.3e-65 218.9 0.0 8.4e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF94706.1 - 3.2e-18 66.0 0.0 4.6e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKF94706.1 - 7.5e-08 32.6 0.0 4.2e-06 26.9 0.1 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKF94706.1 - 0.005 15.7 0.0 0.0093 14.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KKF94706.1 - 0.0081 15.8 0.3 0.022 14.4 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 KKF94706.1 - 0.0095 15.3 0.2 0.02 14.3 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKF94706.1 - 0.017 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Scm3 PF10384.9 KKF94707.1 - 5.6e-23 80.4 0.1 1.3e-22 79.3 0.1 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Menin PF05053.13 KKF94707.1 - 0.011 14.2 1.3 0.016 13.6 1.3 1.2 1 0 0 1 1 1 0 Menin Glyco_hydro_31 PF01055.26 KKF94708.1 - 4.3e-145 484.3 2.3 4.3e-145 484.3 2.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 APG6 PF04111.12 KKF94708.1 - 8.2e-56 188.8 0.0 1.6e-55 187.8 0.0 1.5 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KKF94708.1 - 5.6e-34 117.5 18.2 9.2e-34 116.8 18.2 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region NtCtMGAM_N PF16863.5 KKF94708.1 - 9.3e-30 103.2 0.0 2.1e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KKF94708.1 - 0.0001 22.6 0.3 0.00033 20.9 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like FapA PF03961.13 KKF94708.1 - 0.35 9.4 3.8 0.53 8.8 3.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4448 PF14610.6 KKF94709.1 - 2.4e-28 99.2 0.4 2.9e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) Asp4 PF16996.5 KKF94709.1 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Accessory secretory protein Sec Asp4 DUF348 PF03990.14 KKF94709.1 - 0.059 13.1 0.3 0.16 11.8 0.3 1.8 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain PepSY_2 PF13670.6 KKF94709.1 - 0.14 12.2 0.8 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain PBP1_TM PF14812.6 KKF94709.1 - 0.99 9.8 3.2 2 8.8 3.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tim17 PF02466.19 KKF94711.1 - 7.5e-05 23.1 4.5 0.00014 22.2 3.8 1.7 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 KKF94711.1 - 0.091 13.1 2.3 1.3 9.4 0.1 3.0 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 GNAT_acetyltr_2 PF13718.6 KKF94712.1 - 1.2e-95 319.2 0.0 2.7e-95 318.1 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KKF94712.1 - 4.4e-90 301.5 0.0 6.9e-90 300.9 0.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KKF94712.1 - 1.9e-64 216.8 0.1 5.3e-64 215.3 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KKF94712.1 - 1.8e-32 111.1 0.0 4.8e-32 109.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KKF94712.1 - 0.00026 20.8 0.2 0.022 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKF94712.1 - 0.00049 20.4 0.0 0.024 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain GHMP_kinases_N PF00288.26 KKF94712.1 - 0.039 14.2 0.5 2 8.7 0.2 2.7 2 0 0 2 2 2 0 GHMP kinases N terminal domain Vps54 PF07928.12 KKF94712.1 - 0.12 12.8 0.2 0.28 11.6 0.2 1.5 1 0 0 1 1 1 0 Vps54-like protein DUF1713 PF08213.11 KKF94713.1 - 1.2e-08 34.7 21.3 1.2e-08 34.7 21.3 2.1 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KKF94713.1 - 0.037 14.8 0.2 0.091 13.5 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Mpv17_PMP22 PF04117.12 KKF94714.1 - 4.6e-20 71.6 0.2 7.8e-20 70.9 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Cyclin_N PF00134.23 KKF94715.1 - 7.8e-39 132.3 1.0 1.7e-38 131.3 1.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKF94715.1 - 1.9e-10 40.9 0.1 1.9e-10 40.9 0.1 3.3 3 1 1 4 4 4 1 Cyclin, C-terminal domain PsbQ PF05757.11 KKF94715.1 - 0.063 13.0 3.6 0.15 11.8 3.6 1.6 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Ribosomal_60s PF00428.19 KKF94715.1 - 1.1 9.9 9.2 2.2 8.9 9.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_S5 PF00333.20 KKF94717.1 - 4.4e-27 93.9 0.7 1.1e-26 92.6 0.7 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KKF94717.1 - 1.8e-23 81.8 0.0 3.9e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 KKF94717.1 - 4 8.0 14.7 9.5 6.9 14.7 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Rhodanese PF00581.20 KKF94718.1 - 3e-16 59.8 0.0 1.1e-09 38.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain GEN1_C PF18380.1 KKF94719.1 - 3.3e-24 85.8 0.0 7e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KKF94719.1 - 1.5e-23 83.0 0.0 2.9e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KKF94719.1 - 1.3e-10 41.6 0.0 3.1e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KKF94719.1 - 0.044 13.3 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing Actin PF00022.19 KKF94720.1 - 1.4e-18 66.8 0.0 2.4e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 Actin WW PF00397.26 KKF94721.1 - 1.7e-11 44.0 0.7 1.7e-11 44.0 0.7 2.2 3 0 0 3 3 3 1 WW domain Pga1 PF10333.9 KKF94722.1 - 3.2e-05 23.9 0.0 0.00013 21.9 0.0 1.8 2 0 0 2 2 2 1 GPI-Mannosyltransferase II co-activator Tubulin PF00091.25 KKF94723.1 - 4.6e-67 226.0 0.0 6.9e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKF94723.1 - 8.2e-50 168.2 0.1 1.3e-49 167.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KKF94723.1 - 0.0063 16.2 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain EF-hand_4 PF12763.7 KKF94724.1 - 2.1e-32 111.2 0.0 1.4e-11 44.2 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KKF94724.1 - 3.5e-08 33.8 0.1 0.0017 18.8 0.2 4.7 5 0 0 5 5 5 1 EF-hand domain pair UBA PF00627.31 KKF94724.1 - 4.4e-08 32.9 1.0 1.6e-07 31.1 0.8 2.0 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_1 PF00036.32 KKF94724.1 - 7.7e-08 31.4 0.0 2.3 8.0 0.0 5.5 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 KKF94724.1 - 2.3e-06 27.1 0.2 5.6 7.2 0.2 5.7 5 0 0 5 5 5 1 EF-hand domain DUF3584 PF12128.8 KKF94724.1 - 0.00069 17.3 27.2 0.00092 16.9 27.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Spc7 PF08317.11 KKF94724.1 - 0.0043 16.0 33.2 0.17 10.7 8.6 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF724 PF05266.14 KKF94724.1 - 0.0044 16.9 6.0 0.0044 16.9 6.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF724) IFT57 PF10498.9 KKF94724.1 - 0.016 14.2 17.9 0.034 13.1 17.9 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.9 KKF94724.1 - 0.049 13.7 31.5 0.25 11.4 16.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 KKF94724.1 - 0.076 12.5 31.8 0.018 14.5 26.6 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 KKF94724.1 - 0.079 12.5 16.1 0.14 11.7 16.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATG16 PF08614.11 KKF94724.1 - 0.31 11.2 38.2 0.076 13.2 19.2 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KKF94724.1 - 0.31 11.5 28.9 0.17 12.3 15.8 2.2 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 KKF94724.1 - 0.45 10.6 15.6 0.24 11.4 3.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4298 PF14131.6 KKF94724.1 - 0.65 10.0 4.2 2 8.4 4.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) APG6_N PF17675.1 KKF94724.1 - 0.75 10.3 33.0 6.1 7.4 11.3 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region GAS PF13851.6 KKF94724.1 - 1.2 8.4 32.6 0.23 10.8 15.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Occludin_ELL PF07303.13 KKF94724.1 - 1.8 9.3 14.8 0.91 10.3 3.4 3.0 2 1 1 3 3 3 0 Occludin homology domain Med30 PF11315.8 KKF94724.1 - 1.9 8.7 15.8 0.46 10.7 11.5 1.9 1 1 1 2 2 2 0 Mediator complex subunit 30 FUSC PF04632.12 KKF94724.1 - 2.7 6.4 11.0 4.2 5.8 11.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AIP3 PF03915.13 KKF94724.1 - 3.2 6.8 19.6 5 6.1 19.6 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 DUF4472 PF14739.6 KKF94724.1 - 3.3 8.5 24.3 0.38 11.5 11.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) MscS_porin PF12795.7 KKF94724.1 - 4.2 6.8 51.3 2.3 7.7 28.4 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Csm1_N PF18504.1 KKF94724.1 - 4.8 7.6 22.7 0.44 10.9 1.6 3.8 3 1 1 4 4 4 0 Csm1 N-terminal domain Filament PF00038.21 KKF94724.1 - 6.9 6.1 30.0 4.3 6.8 15.5 2.7 1 1 1 2 2 2 0 Intermediate filament protein DUF3450 PF11932.8 KKF94724.1 - 7.6 5.8 35.1 2.1 7.6 11.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 KKF94724.1 - 8.8 6.4 36.3 9.2 6.3 16.7 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 KKF94724.1 - 9.4 5.2 32.9 4.4 6.3 13.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec6 PF06046.13 KKF94725.1 - 8.6e-159 529.6 7.3 8.6e-159 529.6 7.3 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KKF94725.1 - 0.029 13.3 11.7 0.0093 15.0 6.6 2.7 3 1 0 3 3 3 0 Vps53-like, N-terminal YgaB PF14182.6 KKF94725.1 - 0.24 11.8 3.6 0.9 10.0 0.1 3.1 1 1 2 3 3 3 0 YgaB-like protein Apolipoprotein PF01442.18 KKF94725.1 - 3.9 7.3 16.8 0.12 12.2 0.4 4.1 3 1 1 4 4 4 0 Apolipoprotein A1/A4/E domain LsmAD PF06741.13 KKF94727.1 - 1.9e-26 92.4 0.8 1.9e-26 92.4 0.8 2.2 2 0 0 2 2 2 1 LsmAD domain THEG4 PF15834.5 KKF94727.1 - 0.09 12.8 0.9 0.17 11.9 0.9 1.5 1 0 0 1 1 1 0 Testis highly expressed protein 4 Peptidase_M16 PF00675.20 KKF94728.1 - 2.6e-17 63.2 0.0 5.2e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KKF94728.1 - 0.00018 21.6 0.0 0.00044 20.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.13 KKF94729.1 - 5.6e-44 150.8 0.3 8.3e-44 150.3 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KKF94729.1 - 3.7e-15 55.8 3.4 1.7e-13 50.4 0.1 3.9 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KKF94729.1 - 3.1e-06 27.0 0.0 0.0052 16.6 0.2 2.8 2 0 0 2 2 2 2 TFIIE alpha subunit Mito_carr PF00153.27 KKF94730.1 - 2.1e-24 85.3 0.2 8.3e-15 54.5 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Apolipoprotein PF01442.18 KKF94731.1 - 0.00037 20.4 91.9 0.0016 18.4 0.5 11.0 5 2 3 9 9 9 4 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KKF94731.1 - 0.0022 18.1 88.5 0.0035 17.4 2.9 13.9 7 3 4 12 12 12 4 Baculovirus polyhedron envelope protein, PEP, C terminus TilS PF09179.11 KKF94731.1 - 0.17 12.4 0.0 0.72 10.4 0.0 2.1 1 0 0 1 1 1 0 TilS substrate binding domain HSBP1 PF06825.12 KKF94731.1 - 0.59 10.0 25.4 4.8 7.1 0.4 10.0 9 2 1 10 10 10 0 Heat shock factor binding protein 1 tRNA-synt_2b PF00587.25 KKF94732.1 - 2e-20 73.5 0.0 3.1e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KKF94732.1 - 1.6e-08 34.7 0.2 2.7e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Phe_tRNA-synt_N PF02912.18 KKF94732.1 - 0.071 13.1 1.3 0.16 11.9 1.3 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF3086 PF11285.8 KKF94732.1 - 0.087 11.9 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) TipAS PF07739.13 KKF94732.1 - 0.13 12.8 0.3 0.3 11.6 0.3 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain PHC2_SAM_assoc PF16616.5 KKF94733.1 - 0.32 11.8 3.1 0.89 10.4 3.1 1.7 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DENN PF02141.21 KKF94734.1 - 4.4e-40 137.6 0.1 8e-40 136.8 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KKF94734.1 - 1.8e-07 31.8 0.0 8.6e-07 29.6 0.0 2.3 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.11 KKF94734.1 - 0.0059 17.1 3.7 0.03 14.8 3.7 2.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Dfp1_Him1_M PF08630.10 KKF94734.1 - 0.085 13.1 1.0 12 6.2 1.8 2.6 2 0 0 2 2 2 0 Dfp1/Him1, central region Pirin PF02678.16 KKF94736.1 - 1.6e-30 105.2 0.1 4.7e-30 103.7 0.0 1.8 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 KKF94736.1 - 7.9e-26 90.4 0.0 3.3e-24 85.2 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KKF94736.1 - 1.2e-08 34.5 0.4 2.5e-05 23.9 0.4 2.5 2 1 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KKF94736.1 - 0.0015 18.1 0.3 0.27 11.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CFEM PF05730.11 KKF94737.1 - 9.8e-14 51.2 8.9 1.8e-13 50.4 8.9 1.4 1 0 0 1 1 1 1 CFEM domain Chromo PF00385.24 KKF94738.1 - 1.7e-12 47.1 0.5 1.7e-12 47.1 0.5 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KKF94738.1 - 0.63 10.2 6.0 12 6.1 0.2 3.0 3 0 0 3 3 3 0 Chromo shadow domain Moulting_cycle PF04870.16 KKF94739.1 - 0.028 13.7 8.3 0.067 12.5 8.3 1.6 1 0 0 1 1 1 0 Moulting cycle DUF4638 PF15472.6 KKF94739.1 - 0.14 11.8 13.8 0.019 14.7 9.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) EMC3_TMCO1 PF01956.16 KKF94739.1 - 0.47 10.2 3.5 0.98 9.1 3.5 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RR_TM4-6 PF06459.12 KKF94739.1 - 0.9 9.3 15.4 2 8.2 15.4 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.6 KKF94739.1 - 1.3 7.3 5.5 2 6.7 5.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spore_III_AF PF09581.10 KKF94739.1 - 1.4 8.9 10.5 3.6 7.6 9.9 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Peptidase_S64 PF08192.11 KKF94739.1 - 1.6 7.1 11.9 2.9 6.3 11.9 1.4 1 0 0 1 1 1 0 Peptidase family S64 Cwf_Cwc_15 PF04889.12 KKF94739.1 - 3.1 7.5 26.4 0.89 9.2 21.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF1980 PF09323.10 KKF94739.1 - 4.2 7.3 7.0 8 6.3 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CemA PF03040.14 KKF94739.1 - 4.3 7.2 7.2 10 6.0 7.2 1.5 1 0 0 1 1 1 0 CemA family Nop25 PF09805.9 KKF94739.1 - 4.5 7.7 25.0 17 5.8 25.0 1.9 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SLC12 PF03522.15 KKF94739.1 - 6.9 5.6 16.7 17 4.3 16.7 1.6 1 0 0 1 1 1 0 Solute carrier family 12 Plasmodium_Vir PF05795.11 KKF94739.1 - 9.4 5.5 7.5 18 4.6 7.5 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein tRNA-synt_2 PF00152.20 KKF94740.1 - 3.3e-75 253.1 0.4 4.5e-75 252.7 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKF94740.1 - 3.1e-11 43.1 0.0 5.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KKF94740.1 - 1.4e-06 27.9 0.1 0.0067 15.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) IHABP4_N PF16174.5 KKF94740.1 - 4.4 7.9 13.3 0.84 10.2 5.8 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal COX15-CtaA PF02628.15 KKF94741.1 - 5.2e-110 367.5 10.7 6.7e-110 367.2 10.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein SR-25 PF10500.9 KKF94741.1 - 2.9 7.5 9.9 4 7.0 9.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BASP1 PF05466.12 KKF94741.1 - 4.8 7.1 8.0 6.9 6.6 8.0 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Utp14 PF04615.13 KKF94742.1 - 3.5e-177 591.4 69.4 3.5e-177 591.4 69.4 2.0 1 1 1 2 2 2 1 Utp14 protein Na_Ca_ex PF01699.24 KKF94743.1 - 1.2e-44 151.9 42.4 1.3e-25 90.1 14.7 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein T4SS_CagC PF16943.5 KKF94743.1 - 0.079 13.1 0.2 0.079 13.1 0.2 2.9 2 2 1 4 4 4 0 Cag pathogenicity island, type IV secretory system Lambda_Bor PF06291.11 KKF94743.1 - 0.084 12.9 0.3 0.5 10.4 0.1 2.2 2 0 0 2 2 2 0 Bor protein Glyco_hydro81C PF17652.1 KKF94744.1 - 5.1e-128 427.2 5.9 6.7e-128 426.8 2.9 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KKF94744.1 - 1.5e-108 362.8 3.6 2.2e-108 362.2 3.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Pro-rich PF15240.6 KKF94744.1 - 0.36 11.1 20.1 0.6 10.4 20.1 1.2 1 0 0 1 1 1 0 Proline-rich Transformer PF06495.11 KKF94744.1 - 9 6.3 9.3 16 5.5 9.3 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein Stn1 PF10451.9 KKF94745.1 - 3.8e-14 52.3 0.1 7.9e-13 48.0 0.1 2.1 1 1 0 1 1 1 1 Telomere regulation protein Stn1 DnaJ PF00226.31 KKF94746.1 - 2.5e-21 75.6 0.6 2.5e-21 75.6 0.6 2.0 2 0 0 2 2 2 1 DnaJ domain SIMPL PF04402.14 KKF94746.1 - 0.0053 17.2 4.6 0.0087 16.5 4.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF541) DUF1488 PF07369.11 KKF94746.1 - 0.035 14.1 2.1 0.13 12.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) PNPase PF03726.14 KKF94746.1 - 4.2 7.9 15.2 7.6 7.1 1.2 4.2 3 1 0 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Piwi PF02171.17 KKF94747.1 - 3.1e-66 223.7 0.0 5e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 KKF94747.1 - 5.9e-12 45.7 0.0 1.4e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoN PF16486.5 KKF94747.1 - 9.9e-12 45.7 0.0 1.7e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KKF94747.1 - 1.3e-09 37.6 0.0 3.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KKF94747.1 - 6.3e-05 22.8 0.1 0.00017 21.4 0.1 1.8 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KKF94747.1 - 0.014 15.6 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 Mid domain of argonaute SRP40_C PF05022.12 KKF94749.1 - 1e-12 48.7 2.3 1e-12 48.7 2.3 3.0 2 0 0 2 2 2 1 SRP40, C-terminal domain zf-C3HC PF07967.13 KKF94750.1 - 1.3e-35 122.4 0.3 1.2e-31 109.4 0.7 2.5 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KKF94750.1 - 3.5e-23 81.6 0.0 3.5e-23 81.6 0.0 3.1 3 1 0 3 3 3 1 Rsm1-like VHS PF00790.19 KKF94750.1 - 9.1e-15 54.7 0.0 1.8e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KKF94750.1 - 3.5e-06 27.2 0.9 7.9e-06 26.1 0.9 1.6 1 0 0 1 1 1 1 GAT domain BIR PF00653.21 KKF94750.1 - 0.007 17.0 0.1 0.086 13.5 0.2 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-C2H2 PF00096.26 KKF94751.1 - 3e-19 68.3 27.4 0.00011 22.5 0.8 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKF94751.1 - 4.1e-15 55.4 27.5 9.4e-06 25.8 1.9 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKF94751.1 - 5.4e-11 42.4 23.5 0.0055 17.4 1.2 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKF94751.1 - 1.6e-05 25.1 0.4 6 7.3 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KKF94751.1 - 0.026 15.2 0.9 0.026 15.2 0.9 2.9 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KKF94751.1 - 0.054 13.3 9.3 1.7 8.5 0.7 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KKF94751.1 - 0.054 13.9 7.7 8.2 7.0 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KKF94751.1 - 0.099 12.8 3.4 4.7 7.3 0.2 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger XPA_N PF01286.18 KKF94751.1 - 0.21 11.6 3.9 0.65 10.1 0.2 2.8 3 0 0 3 3 3 0 XPA protein N-terminal Ino80_Iec3 PF14612.6 KKF94751.1 - 0.53 10.9 5.4 5.1 7.7 1.8 2.3 2 0 0 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling zf-C2HC_2 PF13913.6 KKF94751.1 - 5.1 7.1 9.7 4.6 7.2 0.9 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type TFIIA PF03153.13 KKF94751.1 - 7.2 6.5 32.0 0.045 13.8 8.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TFA2_Winged_2 PF18121.1 KKF94752.1 - 9.1e-23 79.7 0.1 2.1e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KKF94752.1 - 4.6e-14 52.5 0.1 1.2e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 TFIIE beta subunit core domain Cyt-b5 PF00173.28 KKF94753.1 - 2.3e-24 85.3 0.1 3.2e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-actin_cap_A PF01267.17 KKF94754.1 - 8.8e-93 310.6 0.0 9.9e-93 310.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ACAS_N PF16177.5 KKF94754.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus Transket_pyr PF02779.24 KKF94755.1 - 3.4e-35 121.3 0.6 4.3e-32 111.2 0.6 2.4 1 1 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KKF94755.1 - 3.9e-32 110.7 0.1 1.2e-31 109.2 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain TyeA PF09059.10 KKF94755.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 TyeA Cellulase PF00150.18 KKF94756.1 - 1.1e-09 38.2 0.3 2.4e-09 37.0 0.3 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ODV-E18 PF10717.9 KKF94756.1 - 0.014 15.2 2.7 0.035 14.0 2.7 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4064 PF13273.6 KKF94756.1 - 0.064 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) AA_permease_2 PF13520.6 KKF94756.1 - 0.087 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease TMEM154 PF15102.6 KKF94756.1 - 0.13 12.2 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF3446 PF11928.8 KKF94756.1 - 1.2 9.5 9.9 0.31 11.4 0.7 3.1 3 0 0 3 3 3 0 Early growth response N-terminal domain MFS_1 PF07690.16 KKF94757.1 - 3.7e-41 141.2 34.9 3.7e-41 141.2 34.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKF94757.1 - 1.1e-08 34.1 2.1 1.6e-08 33.5 2.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PAS PF00989.25 KKF94758.1 - 7.8e-05 22.6 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KKF94758.1 - 0.0024 17.9 8.5 0.0055 16.8 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.10 KKF94758.1 - 0.039 14.2 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold Flavokinase PF01687.17 KKF94759.1 - 7.3e-35 119.6 0.0 8.7e-35 119.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase FAD_binding_3 PF01494.19 KKF94761.1 - 8.2e-23 81.2 0.0 2.3e-21 76.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKF94761.1 - 1.2e-06 28.0 0.0 0.048 12.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKF94761.1 - 0.00026 20.4 0.0 0.085 12.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KKF94761.1 - 0.00037 19.6 0.0 0.0047 16.0 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.14 KKF94761.1 - 0.00066 18.5 0.0 0.41 9.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 KKF94761.1 - 0.0017 17.5 0.0 1.2 8.1 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.27 KKF94761.1 - 0.008 16.7 0.0 0.29 11.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKF94761.1 - 0.0096 14.8 0.1 2.6 6.8 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KKF94761.1 - 0.011 16.0 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKF94761.1 - 0.099 12.6 0.1 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KKF94761.1 - 0.15 11.6 0.1 3.1 7.3 0.1 2.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKF94761.1 - 0.24 10.5 0.2 1 8.4 0.3 1.9 1 1 1 2 2 2 0 FAD binding domain DUF2457 PF10446.9 KKF94762.1 - 1.1 8.3 4.6 1.6 7.8 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) OPT PF03169.15 KKF94763.1 - 1.5e-166 555.7 52.3 1.7e-166 555.5 52.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AAA PF00004.29 KKF94764.1 - 1.8e-40 138.5 0.0 4.7e-40 137.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKF94764.1 - 1.9e-17 62.9 0.1 3.9e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KKF94764.1 - 7.6e-08 32.0 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KKF94764.1 - 0.0001 22.3 0.0 0.00041 20.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KKF94764.1 - 0.00029 20.6 0.0 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKF94764.1 - 0.00037 20.9 2.0 0.03 14.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain CDC73_N PF16050.5 KKF94764.1 - 0.00094 18.6 0.2 0.0017 17.8 0.2 1.4 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal AAA_22 PF13401.6 KKF94764.1 - 0.0011 19.2 1.1 0.099 12.9 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KKF94764.1 - 0.0015 18.7 0.0 0.0096 16.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KKF94764.1 - 0.0019 17.7 0.2 0.058 12.8 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KKF94764.1 - 0.0063 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KKF94764.1 - 0.017 14.3 0.0 0.039 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KKF94764.1 - 0.017 15.3 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KKF94764.1 - 0.056 13.2 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KKF94764.1 - 0.091 12.5 2.1 0.28 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKF94764.1 - 0.096 12.2 0.0 0.26 10.8 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KKF94764.1 - 0.11 12.2 0.1 0.33 10.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain Ribosomal_L10 PF00466.20 KKF94765.1 - 0.0036 17.4 0.0 0.11 12.7 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L10 RNA_lig_T4_1 PF09511.10 KKF94766.1 - 1.3e-85 286.7 0.0 2.1e-85 286.1 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 KKF94766.1 - 2.2e-76 256.7 0.3 2.9e-76 256.3 0.3 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 KKF94766.1 - 5.3e-50 169.8 0.0 1.3e-49 168.5 0.0 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain Ank_5 PF13857.6 KKF94767.1 - 5.5e-09 36.1 0.0 2.4e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKF94767.1 - 2.5e-07 31.1 0.0 5.4e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKF94767.1 - 4.3e-05 24.0 0.0 0.00027 21.4 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKF94767.1 - 0.0069 16.8 0.0 0.079 13.6 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat MLTR_LBD PF17765.1 KKF94767.1 - 0.11 12.7 0.3 0.51 10.4 0.0 2.0 2 1 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain UPF0020 PF01170.18 KKF94768.1 - 4.9e-09 36.2 0.0 0.00011 21.9 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Mago_nashi PF02792.14 KKF94769.1 - 1e-65 220.2 0.1 1.2e-65 219.9 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein UBD PF16455.5 KKF94770.1 - 2.4e-30 104.9 0.0 4.2e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-binding domain SET PF00856.28 KKF94770.1 - 3.3e-15 56.9 0.0 1.4e-14 54.9 0.0 2.0 2 1 0 2 2 2 1 SET domain ubiquitin PF00240.23 KKF94770.1 - 6.8e-10 38.6 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KKF94770.1 - 0.00027 21.5 0.0 0.00064 20.3 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KKF94770.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like LT-IIB PF06453.11 KKF94770.1 - 0.038 13.9 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Pre-SET PF05033.16 KKF94770.1 - 0.039 14.6 0.0 0.13 12.9 0.0 1.8 2 0 0 2 2 2 0 Pre-SET motif Rad60-SLD_2 PF13881.6 KKF94770.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Cu-oxidase_3 PF07732.15 KKF94771.1 - 3.8e-40 136.6 6.6 4e-39 133.3 4.1 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKF94771.1 - 8.1e-35 119.5 11.8 1.1e-33 115.8 1.3 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKF94771.1 - 7e-31 107.5 0.8 4.4e-27 95.2 0.0 3.1 3 1 0 3 3 3 2 Multicopper oxidase CARDB PF07705.11 KKF94771.1 - 0.047 14.0 0.2 0.1 12.9 0.2 1.5 1 0 0 1 1 1 0 CARDB Phosphoesterase PF04185.14 KKF94772.1 - 3.5e-33 115.3 2.7 4e-32 111.8 2.7 2.1 1 1 0 1 1 1 1 Phosphoesterase family B-block_TFIIIC PF04182.12 KKF94773.1 - 2.3e-17 62.9 0.0 1.4e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC Metallophos PF00149.28 KKF94774.1 - 7.1e-37 127.9 0.2 1.6e-36 126.8 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.6 KKF94775.1 - 1.2e-46 159.2 2.4 1.9e-46 158.6 2.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKF94775.1 - 2e-27 95.9 4.9 9.4e-27 93.7 4.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKF94775.1 - 1.8e-06 28.0 0.6 2.5e-06 27.5 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKF94775.1 - 0.00063 19.3 0.2 0.1 12.0 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family TauD PF02668.16 KKF94776.1 - 1e-35 123.9 0.0 1.5e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KKF94776.1 - 2.7e-15 56.8 0.0 1.1e-14 54.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) PhoD PF09423.10 KKF94777.1 - 2.9e-42 144.9 0.0 8.2e-42 143.5 0.0 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase EMP24_GP25L PF01105.24 KKF94778.1 - 6.4e-45 153.3 1.0 7.3e-45 153.1 1.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 KKF94778.1 - 0.059 13.8 0.2 1.1 9.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) AgI_II_C2 PF17998.1 KKF94778.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Cell surface antigen I/II C2 terminal domain UQ_con PF00179.26 KKF94779.1 - 4.3e-21 75.0 0.0 7.1e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Kazal_3 PF18434.1 KKF94779.1 - 0.031 14.0 0.3 0.066 13.0 0.3 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain RWD PF05773.22 KKF94779.1 - 0.084 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 RWD domain P5-ATPase PF12409.8 KKF94780.1 - 2.1e-36 124.8 0.0 6.2e-36 123.3 0.0 1.9 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KKF94780.1 - 1.4e-27 96.4 0.0 3.4e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KKF94780.1 - 7e-09 36.3 0.0 2.3e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KKF94780.1 - 3.2e-08 33.5 4.3 1e-07 31.8 4.3 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus LIME1 PF15332.6 KKF94780.1 - 0.014 15.0 2.4 0.059 13.0 0.9 2.2 2 0 0 2 2 2 0 Lck-interacting transmembrane adapter 1 Cation_ATPase_N PF00690.26 KKF94780.1 - 0.015 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KKF94780.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Cation transport ATPase (P-type) NAP PF00956.18 KKF94781.1 - 1.9e-94 315.8 9.8 1.9e-94 315.8 9.8 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.13 KKF94781.1 - 0.054 13.5 17.5 0.098 12.6 17.5 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 KKF94781.1 - 1.1 9.4 30.3 2.4 8.3 20.4 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Aminotran_5 PF00266.19 KKF94782.1 - 1.4e-30 106.5 0.0 3.8e-22 78.8 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-V PorB PF11565.8 KKF94782.1 - 0.092 13.2 0.4 0.58 10.6 0.1 2.2 1 1 1 2 2 2 0 Alpha helical Porin B 2-Hacid_dh_C PF02826.19 KKF94783.1 - 6.2e-51 172.3 0.0 9.9e-51 171.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKF94783.1 - 3e-36 124.0 0.0 4e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKF94783.1 - 7.8e-05 22.9 0.2 0.00017 21.8 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 KKF94783.1 - 0.0035 17.1 0.1 0.0081 15.9 0.1 1.7 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.21 KKF94783.1 - 0.0091 16.1 0.1 0.026 14.6 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KKF94783.1 - 0.027 15.0 0.0 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain PilM_2 PF11104.8 KKF94783.1 - 0.079 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Myosin_head PF00063.21 KKF94784.1 - 1e-259 863.4 0.7 1.8e-259 862.6 0.7 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KKF94784.1 - 2.5e-26 92.0 2.7 2.5e-26 92.0 2.7 2.6 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KKF94784.1 - 1.9e-17 61.3 37.2 2.6e-05 23.6 0.9 7.4 5 1 2 7 7 7 4 IQ calmodulin-binding motif GAS PF13851.6 KKF94784.1 - 0.00019 20.9 25.4 0.0044 16.4 25.1 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 KKF94784.1 - 0.011 14.7 20.5 0.024 13.5 20.5 1.5 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_16 PF13191.6 KKF94784.1 - 0.012 16.0 2.8 0.018 15.4 0.0 2.7 3 0 0 3 3 2 0 AAA ATPase domain AAA_22 PF13401.6 KKF94784.1 - 0.013 15.7 0.0 0.063 13.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF812 PF05667.11 KKF94784.1 - 0.017 14.1 21.2 0.031 13.2 21.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Myosin_N PF02736.19 KKF94784.1 - 0.017 14.9 0.4 0.017 14.9 0.4 2.1 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Fez1 PF06818.15 KKF94784.1 - 0.29 11.6 22.7 0.15 12.5 8.2 2.8 1 1 1 2 2 2 0 Fez1 Sec34 PF04136.15 KKF94784.1 - 0.3 11.0 10.4 0.14 12.0 6.8 2.3 1 1 1 2 2 2 0 Sec34-like family Dna2 PF08696.11 KKF94784.1 - 0.54 10.0 4.7 1.7 8.4 4.7 1.9 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF724 PF05266.14 KKF94784.1 - 0.9 9.3 19.0 0.42 10.4 6.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Rx_N PF18052.1 KKF94784.1 - 1.8 8.9 7.0 12 6.2 3.8 3.6 3 0 0 3 3 3 0 Rx N-terminal domain KASH_CCD PF14662.6 KKF94784.1 - 2 8.2 26.4 1.4 8.7 22.0 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 KKF94784.1 - 2.9 8.4 16.2 0.51 10.8 0.2 4.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.11 KKF94784.1 - 3.7 7.3 17.6 2.9 7.7 7.5 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 HMMR_N PF15905.5 KKF94784.1 - 3.8 6.9 22.7 7.8 5.9 22.7 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 KKF94784.1 - 4.2 7.6 24.1 13 6.1 11.1 3.0 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 KKF94784.1 - 4.7 7.3 27.9 3.1 7.8 24.0 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ERM PF00769.19 KKF94784.1 - 7.5 6.3 30.3 1.3e+02 2.2 30.4 2.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Baculo_PEP_C PF04513.12 KKF94784.1 - 8.1 6.5 12.4 4.9 7.2 8.0 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Noelin-1 PF12308.8 KKF94784.1 - 9 6.3 9.0 0.93 9.5 3.0 2.6 2 0 0 2 2 2 0 Neurogenesis glycoprotein AAA_18 PF13238.6 KKF94785.1 - 9e-28 97.4 0.5 2e-27 96.3 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KKF94785.1 - 1.3e-09 38.6 0.0 6.7e-09 36.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 KKF94785.1 - 8.9e-05 22.6 0.1 0.0035 17.4 0.0 2.2 2 1 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.6 KKF94785.1 - 0.00014 22.0 0.0 0.056 13.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 KKF94785.1 - 0.00016 21.7 0.5 0.00041 20.3 0.1 1.9 2 1 0 2 2 2 1 NTPase AAA PF00004.29 KKF94785.1 - 0.00017 22.0 0.0 0.00097 19.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KKF94785.1 - 0.0016 18.8 0.0 0.0029 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase dNK PF01712.19 KKF94785.1 - 0.0018 18.1 0.7 0.66 9.8 0.1 2.2 1 1 0 2 2 2 2 Deoxynucleoside kinase SKI PF01202.22 KKF94785.1 - 0.003 17.7 0.6 0.054 13.6 0.6 2.2 1 1 0 1 1 1 1 Shikimate kinase Thymidylate_kin PF02223.17 KKF94785.1 - 0.0031 17.2 0.1 0.7 9.5 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.6 KKF94785.1 - 0.0038 17.5 0.0 0.01 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KKF94785.1 - 0.005 17.1 0.8 0.0099 16.1 0.3 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KKF94785.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKF94785.1 - 0.01 16.2 0.1 0.02 15.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KKF94785.1 - 0.016 15.6 0.3 0.064 13.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 KKF94785.1 - 0.017 15.4 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain KTI12 PF08433.10 KKF94785.1 - 0.06 12.8 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 KKF94785.1 - 0.13 12.0 0.7 0.2 11.4 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNaseH_like PF04308.12 KKF94785.1 - 0.14 12.0 0.2 0.21 11.5 0.2 1.2 1 0 0 1 1 1 0 Ribonuclease H-like Ham1p_like PF01725.16 KKF94786.1 - 1.7e-54 184.6 0.0 1.9e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family tRNA-synt_2b PF00587.25 KKF94787.1 - 1.1e-36 126.5 0.0 1.9e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KKF94787.1 - 5e-17 62.1 7.2 9.2e-17 61.2 7.2 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ATF7IP_BD PF16788.5 KKF94787.1 - 0.012 15.7 2.0 0.026 14.6 2.0 1.5 1 0 0 1 1 1 0 ATF-interacting protein binding domain Ras PF00071.22 KKF94788.1 - 1.5e-42 144.9 0.1 1.8e-42 144.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF94788.1 - 1.5e-13 51.0 0.0 2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF94788.1 - 3e-05 23.6 0.0 3.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KKF94788.1 - 0.00012 22.0 0.1 0.015 15.2 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 KKF94788.1 - 0.00027 21.0 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKF94788.1 - 0.00029 20.4 0.0 0.00043 19.9 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KKF94788.1 - 0.0037 16.8 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KKF94788.1 - 0.071 12.5 0.0 0.36 10.2 0.0 2.2 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit UPRTase PF14681.6 KKF94789.1 - 2.3e-69 233.0 0.0 2.7e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KKF94789.1 - 0.0068 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Elf1 PF05129.13 KKF94790.1 - 3.4e-28 97.5 0.0 3.9e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like PHD_4 PF16866.5 KKF94790.1 - 0.026 14.6 0.3 0.036 14.2 0.3 1.4 1 1 0 1 1 1 0 PHD-finger zf-Sec23_Sec24 PF04810.15 KKF94790.1 - 2.1 8.4 7.8 11 6.2 2.0 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Ribosomal_S3Ae PF01015.18 KKF94791.1 - 1e-89 299.5 2.5 1.3e-89 299.2 2.5 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KKF94791.1 - 0.0062 17.0 0.1 0.023 15.2 0.0 2.1 1 1 0 2 2 2 1 Translation initiation factor SUI1 Ribosomal_L22 PF00237.19 KKF94791.1 - 0.034 14.4 0.2 0.067 13.4 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e NEMO PF11577.8 KKF94791.1 - 0.06 13.4 1.8 0.27 11.3 0.0 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Abhydro_lipase PF04083.16 KKF94791.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region TipAS PF07739.13 KKF94791.1 - 0.11 13.0 0.1 2.5 8.7 0.0 2.5 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Na_H_Exchanger PF00999.21 KKF94792.1 - 8.9e-44 149.8 34.3 1.4e-43 149.1 34.3 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Syndecan PF01034.20 KKF94792.1 - 0.19 11.6 0.2 1.2 9.2 0.2 2.5 1 0 0 1 1 1 0 Syndecan domain Exo_endo_phos PF03372.23 KKF94793.1 - 1.6e-11 44.2 0.4 2.5e-11 43.5 0.4 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NADH-u_ox-rdase PF10785.9 KKF94794.1 - 1.8e-29 102.2 0.1 3.8e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KKF94794.1 - 8.5e-27 93.0 0.1 1.2e-26 92.5 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DSHCT PF08148.12 KKF94795.1 - 4.7e-53 179.2 0.2 1.1e-52 178.1 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 KKF94795.1 - 5.7e-21 75.6 0.6 9.9e-21 74.9 0.1 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 KKF94795.1 - 9.7e-19 67.8 0.0 2.3e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF94795.1 - 2.4e-06 27.8 0.0 7.7e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF94795.1 - 3.1e-05 24.0 0.1 7e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KKF94795.1 - 0.13 12.6 0.1 0.66 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain Transket_pyr PF02779.24 KKF94796.1 - 2.3e-44 151.2 0.0 3.7e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KKF94796.1 - 5.7e-37 126.4 0.1 1.7e-36 124.9 0.1 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Tetraspanin PF00335.20 KKF94797.1 - 7.2e-07 29.2 9.5 1e-06 28.6 9.5 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF4191 PF13829.6 KKF94797.1 - 0.049 13.0 3.9 0.72 9.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF4064 PF13273.6 KKF94797.1 - 0.31 11.3 8.8 1.6 9.1 3.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4131 PF13567.6 KKF94797.1 - 0.51 10.0 3.0 1.2 8.8 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FxsA PF04186.13 KKF94797.1 - 0.62 10.2 9.9 1.7 8.8 0.2 3.1 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein Mg_trans_NIPA PF05653.14 KKF94798.1 - 1.7e-14 53.7 13.6 7.6e-14 51.5 13.6 1.8 1 1 0 1 1 1 1 Magnesium transporter NIPA PUNUT PF16913.5 KKF94798.1 - 0.00016 21.0 0.2 0.00016 21.0 0.2 2.1 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 KKF94798.1 - 0.00094 19.4 1.8 0.00094 19.4 1.8 3.2 3 1 1 4 4 4 2 EamA-like transporter family DUF5539 PF17693.1 KKF94798.1 - 0.0075 16.0 0.9 0.014 15.1 0.3 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5539) Neurensin PF14927.6 KKF94798.1 - 0.88 9.3 4.3 0.87 9.3 0.6 2.7 3 0 0 3 3 3 0 Neurensin Abhydrolase_9_N PF15420.6 KKF94798.1 - 4.5 7.2 10.4 5.5 6.9 7.4 2.5 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus vATP-synt_E PF01991.18 KKF94799.1 - 1.9e-63 213.5 9.6 2.2e-63 213.3 9.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2255 PF10012.9 KKF94799.1 - 0.012 15.8 1.2 0.025 14.7 1.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) Methyltransf_7 PF03492.15 KKF94799.1 - 0.18 11.0 2.6 0.23 10.6 2.6 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase PhoLip_ATPase_C PF16212.5 KKF94801.1 - 9e-77 258.2 29.3 9e-77 258.2 29.3 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKF94801.1 - 1.4e-20 72.7 0.5 4.5e-20 71.1 0.5 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KKF94801.1 - 5.2e-13 48.9 0.0 4.2e-12 46.0 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKF94801.1 - 6e-12 46.3 5.2 9.8e-08 32.5 2.7 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KKF94801.1 - 0.0033 17.0 0.0 0.0033 17.0 0.0 3.3 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KKF94801.1 - 0.018 14.8 0.5 0.04 13.7 0.5 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Herpes_BLLF1 PF05109.13 KKF94801.1 - 0.12 10.3 7.8 0.18 9.8 7.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Aldedh PF00171.22 KKF94802.1 - 2.5e-118 395.5 0.2 2.9e-118 395.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.29 KKF94803.1 - 1e-40 139.3 0.0 2e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ipi1_N PF12333.8 KKF94803.1 - 6.8e-25 87.6 0.1 2.1e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Helicase_C PF00271.31 KKF94803.1 - 8e-23 80.9 0.0 3e-22 79.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FAM35_C PF15793.5 KKF94803.1 - 0.17 11.3 0.0 0.37 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein family FAM35, C-terminal Robl_LC7 PF03259.17 KKF94804.1 - 2.6e-07 30.3 0.1 1.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain DLH PF01738.18 KKF94806.1 - 9.7e-14 51.4 0.0 1.1e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Carboxyl_trans PF01039.22 KKF94807.1 - 3.2e-127 425.2 0.3 7e-124 414.2 0.2 2.0 1 1 1 2 2 2 2 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.24 KKF94808.1 - 7.9e-42 143.0 1.9 1.5e-41 142.1 1.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKF94808.1 - 1.6e-30 106.1 0.0 3.8e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KKF94808.1 - 1.2e-24 86.3 0.1 2.2e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKF94808.1 - 2.5e-15 56.9 0.2 5.3e-15 55.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KKF94808.1 - 0.0039 16.9 0.4 0.024 14.3 0.4 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal RGS PF00615.19 KKF94809.1 - 0.018 15.3 0.1 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Regulator of G protein signaling domain DUF2207 PF09972.9 KKF94809.1 - 0.026 13.3 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Redoxin PF08534.10 KKF94810.1 - 4.1e-30 104.4 0.0 4.3e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KKF94810.1 - 4e-08 33.2 0.0 5.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family FAD_syn PF06574.12 KKF94810.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase Ribosomal_L24e PF01246.20 KKF94811.1 - 2.8e-28 97.9 0.1 2.8e-28 97.9 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e CBP4 PF07960.11 KKF94812.1 - 3.3e-28 98.1 0.9 3.3e-28 98.1 0.9 1.9 2 0 0 2 2 2 1 CBP4 NAC PF01849.18 KKF94812.1 - 1.3e-21 76.3 0.1 2.6e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 NAC domain NOGCT PF08155.11 KKF94812.1 - 0.026 14.5 0.2 0.21 11.6 0.2 2.5 3 0 0 3 3 3 0 NOGCT (NUC087) domain MAGI_u1 PF16663.5 KKF94812.1 - 0.045 13.8 0.1 0.15 12.1 0.1 1.9 1 0 0 1 1 1 0 Unstructured region on MAGI Ebp2 PF05890.12 KKF94812.1 - 0.77 9.3 13.9 0.031 13.8 8.5 1.4 2 0 0 2 2 2 0 Eukaryotic rRNA processing protein EBP2 Synaptobrevin PF00957.21 KKF94813.1 - 9.2e-31 105.5 1.2 1.1e-30 105.3 1.2 1.1 1 0 0 1 1 1 1 Synaptobrevin EMP24_GP25L PF01105.24 KKF94813.1 - 0.022 14.7 0.2 0.03 14.3 0.2 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Duffy_binding PF05424.11 KKF94813.1 - 0.029 14.4 0.7 0.038 14.0 0.7 1.2 1 0 0 1 1 1 0 Duffy binding domain Noelin-1 PF12308.8 KKF94813.1 - 0.068 13.2 0.3 0.097 12.7 0.3 1.2 1 0 0 1 1 1 0 Neurogenesis glycoprotein Glyco_hydro_76 PF03663.14 KKF94814.1 - 7.2e-147 489.7 23.2 8.8e-147 489.4 23.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MLANA PF14991.6 KKF94814.1 - 0.086 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A 2-Hacid_dh_C PF02826.19 KKF94815.1 - 9.8e-44 148.8 0.0 4.2e-28 97.9 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKF94815.1 - 0.0068 16.1 0.0 0.0095 15.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 KKF94815.1 - 0.027 15.0 0.0 0.054 14.0 0.0 1.5 1 1 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 KKF94815.1 - 0.029 14.9 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KKF94815.1 - 0.061 13.2 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAT PF04768.13 KKF94816.1 - 8.5e-45 152.5 0.1 1.8e-44 151.4 0.1 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KKF94816.1 - 2.8e-32 112.3 0.1 2e-31 109.5 0.0 2.1 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 KKF94816.1 - 5.1e-28 97.9 0.0 1.4e-27 96.5 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KKF94816.1 - 0.039 14.1 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ctr PF04145.15 KKF94818.1 - 1.6e-27 97.0 0.1 2.2e-27 96.5 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family SRF-TF PF00319.18 KKF94819.1 - 3.4e-21 74.5 0.2 5.2e-21 73.9 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MRI PF15325.6 KKF94819.1 - 0.44 11.6 3.9 0.19 12.8 0.8 1.9 2 0 0 2 2 2 0 Modulator of retrovirus infection Linker_histone PF00538.19 KKF94820.1 - 3.1e-08 33.8 0.1 1.2e-07 31.9 0.1 2.1 1 0 0 1 1 1 1 linker histone H1 and H5 family AA_permease PF00324.21 KKF94822.1 - 1.1e-102 344.1 37.8 5.1e-73 246.3 18.6 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKF94822.1 - 1.2e-23 83.7 35.8 1.6e-19 70.1 18.3 2.1 1 1 1 2 2 2 2 Amino acid permease TAL_FSA PF00923.19 KKF94824.1 - 2.7e-32 112.3 0.0 3.6e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase HLH PF00010.26 KKF94825.1 - 0.028 14.4 0.1 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 KKF94826.1 - 1.5e-40 139.2 22.7 2e-40 138.8 22.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKF94826.1 - 3.1e-09 36.2 9.6 5.9e-09 35.3 9.6 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KKF94826.1 - 4.4e-09 35.3 2.6 4.4e-09 35.3 2.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KKF94826.1 - 8.2e-05 21.2 1.6 0.00013 20.5 1.6 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector DEAD PF00270.29 KKF94827.1 - 6.7e-44 149.7 0.0 1e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF94827.1 - 1.1e-27 96.5 0.4 8.2e-27 93.7 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KKF94827.1 - 0.1 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TFIIA PF03153.13 KKF94827.1 - 4.4 7.2 31.4 6.5 6.6 31.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GatB_N PF02934.15 KKF94828.1 - 5e-94 314.7 0.0 8e-94 314.1 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KKF94828.1 - 8.4e-08 32.2 0.1 4.1e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 GatB domain FMN_dh PF01070.18 KKF94829.1 - 8.2e-85 284.9 0.1 6.2e-47 160.3 0.1 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Peptidase_M19 PF01244.21 KKF94829.1 - 0.0031 16.7 0.0 0.026 13.7 0.0 1.9 1 1 1 2 2 2 1 Membrane dipeptidase (Peptidase family M19) IMPDH PF00478.25 KKF94829.1 - 0.0077 15.3 0.1 0.013 14.5 0.1 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KKF94829.1 - 0.059 12.8 0.3 6.2 6.2 0.0 2.4 1 1 1 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.17 KKF94829.1 - 0.086 12.0 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 KKF94829.1 - 0.09 12.0 0.2 1.2 8.3 0.0 2.5 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase ThiG PF05690.14 KKF94829.1 - 0.15 11.3 0.0 15 4.8 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Glyco_tranf_2_3 PF13641.6 KKF94830.1 - 2.6e-18 66.8 0.0 3.6e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KKF94830.1 - 9.2e-08 31.7 0.0 2.2e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 ELYS PF13934.6 KKF94831.1 - 6.2e-32 111.4 0.0 9.8e-31 107.4 0.0 2.0 1 1 1 2 2 2 2 Nuclear pore complex assembly NIT PF08376.10 KKF94831.1 - 0.014 15.9 2.4 0.026 15.0 1.9 1.6 1 1 1 2 2 2 0 Nitrate and nitrite sensing SMC_N PF02463.19 KKF94832.1 - 7.4e-76 254.4 7.5 3.8e-75 252.1 7.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKF94832.1 - 2.4e-21 76.2 0.0 1.4e-20 73.8 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KKF94832.1 - 2.3e-10 40.8 11.3 5.2e-05 23.2 0.4 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Tektin PF03148.14 KKF94832.1 - 1.5e-05 23.9 6.1 1.5e-05 23.9 6.1 6.2 3 2 2 5 5 5 2 Tektin family Filament PF00038.21 KKF94832.1 - 0.0005 19.8 4.2 0.0005 19.8 4.2 6.0 2 2 3 5 5 4 1 Intermediate filament protein AAA_13 PF13166.6 KKF94832.1 - 0.00082 18.1 10.1 0.00082 18.1 10.1 5.9 2 2 4 6 6 5 3 AAA domain AAA_29 PF13555.6 KKF94832.1 - 0.00086 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ERM PF00769.19 KKF94832.1 - 0.003 17.4 10.3 0.003 17.4 10.3 6.7 3 2 4 7 7 5 2 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.7 KKF94832.1 - 0.0041 17.3 5.8 0.0041 17.3 5.8 7.3 4 2 3 7 7 5 3 Tropomyosin like DivIC PF04977.15 KKF94832.1 - 0.0093 15.7 0.6 0.0093 15.7 0.6 10.6 6 3 3 10 10 10 1 Septum formation initiator DUF4200 PF13863.6 KKF94832.1 - 0.01 16.2 7.3 0.01 16.2 7.3 8.5 5 3 4 9 9 9 0 Domain of unknown function (DUF4200) NOA36 PF06524.12 KKF94832.1 - 0.55 9.5 15.5 1.6 8.0 15.5 1.9 1 0 0 1 1 1 0 NOA36 protein ABC_tran PF00005.27 KKF94832.1 - 1.1 9.8 0.0 1.1 9.8 0.0 5.8 4 3 0 4 4 3 0 ABC transporter Spc7 PF08317.11 KKF94832.1 - 2.3 7.0 109.0 0.015 14.2 18.0 7.3 3 2 3 7 7 7 0 Spc7 kinetochore protein DUF5082 PF16888.5 KKF94832.1 - 4.6 7.5 72.5 1.8 8.9 4.2 9.2 5 3 0 8 8 8 0 Domain of unknown function (DUF5082) VSP PF03302.13 KKF94834.1 - 0.0039 16.1 7.4 0.0039 16.1 7.4 2.0 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF2207 PF09972.9 KKF94834.1 - 0.0046 15.8 0.1 0.0046 15.8 0.1 1.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) SKG6 PF08693.10 KKF94834.1 - 0.055 12.9 0.0 0.055 12.9 0.0 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ROS_MUCR PF05443.11 KKF94834.1 - 4.3 7.4 5.6 27 4.8 0.4 2.6 2 1 1 3 3 3 0 ROS/MUCR transcriptional regulator protein NAD_binding_6 PF08030.12 KKF94835.1 - 3.9e-31 108.3 0.0 6.1e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKF94835.1 - 4.2e-21 75.1 0.3 4.4e-20 71.8 0.0 2.6 3 0 0 3 3 3 1 FAD-binding domain Ferric_reduct PF01794.19 KKF94835.1 - 1.5e-17 63.9 11.7 1.5e-17 63.9 11.7 1.9 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KKF94835.1 - 0.2 12.3 0.0 0.56 10.9 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain UQ_con PF00179.26 KKF94836.1 - 4.5e-53 178.7 0.0 5.1e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKF94836.1 - 0.0019 18.5 0.0 0.0022 18.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KKF94836.1 - 0.035 13.8 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KKF94836.1 - 0.054 13.4 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.16 KKF94837.1 - 3.2e-25 89.0 0.2 6.2e-25 88.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KKF94837.1 - 3.3e-25 89.0 1.6 5.9e-25 88.2 1.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKF94837.1 - 8.1e-17 61.2 0.0 1.6e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKF94837.1 - 4.2e-07 30.3 1.8 8.8e-07 29.3 1.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Gti1_Pac2 PF09729.9 KKF94838.1 - 6.4e-41 140.4 9.4 3.8e-35 121.6 0.1 3.1 2 2 1 3 3 3 2 Gti1/Pac2 family Retrotran_gag_2 PF14223.6 KKF94839.1 - 0.027 14.2 0.3 0.063 12.9 0.3 1.6 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4487 PF14868.6 KKF94841.1 - 3.7e-05 22.8 0.4 0.039 12.8 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4487) Fungal_trans PF04082.18 KKF94841.1 - 0.0019 17.3 0.4 0.0053 15.8 0.4 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain RAI16-like PF10257.9 KKF94842.1 - 2.3e-66 224.1 0.1 3e-66 223.7 0.1 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Cutinase PF01083.22 KKF94843.1 - 9.6e-06 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Cutinase Peptidase_S41 PF03572.18 KKF94844.1 - 3.2e-09 36.6 0.0 8.1e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Kelch_5 PF13854.6 KKF94844.1 - 0.0049 16.8 0.9 0.087 12.8 0.9 2.7 2 0 0 2 2 2 1 Kelch motif ocr PF08684.10 KKF94844.1 - 0.14 12.6 0.1 0.36 11.3 0.1 1.6 1 0 0 1 1 1 0 DNA mimic ocr CHASE8 PF17152.4 KKF94844.1 - 0.22 11.8 1.6 0.64 10.3 1.6 1.7 1 0 0 1 1 1 0 Periplasmic sensor domain PLDc_2 PF13091.6 KKF94845.1 - 1.2e-18 67.2 0.0 1.2e-11 44.6 0.0 3.7 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KKF94845.1 - 0.00068 19.7 0.1 0.0068 16.5 0.0 2.3 2 0 0 2 2 2 1 Phospholipase D Active site motif Ammonium_transp PF00909.21 KKF94846.1 - 1.3e-119 399.4 28.0 1.5e-119 399.3 28.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PH_10 PF15411.6 KKF94850.1 - 3.2e-40 137.2 0.0 7.6e-40 136.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KKF94850.1 - 1.6e-29 103.5 0.1 2.7e-29 102.7 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 KKF94850.1 - 9.4e-28 96.3 0.1 2e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 CDC24 Calponin WD40 PF00400.32 KKF94851.1 - 5.5e-21 74.5 4.8 6.5e-05 23.6 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat F-box-like PF12937.7 KKF94851.1 - 1.1e-09 38.0 3.8 2.5e-09 36.9 3.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKF94851.1 - 2.7e-06 27.1 1.6 7.2e-06 25.7 1.6 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KKF94851.1 - 3e-05 24.2 6.2 0.086 13.2 0.0 3.9 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain MgtE_N PF03448.17 KKF94851.1 - 0.013 16.1 0.0 0.034 14.8 0.0 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain Sin_N PF04801.13 KKF94851.1 - 0.02 14.1 6.2 0.034 13.4 6.2 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region BBS2_Mid PF14783.6 KKF94851.1 - 0.031 14.3 0.1 27 4.8 0.0 3.7 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Snf7 PF03357.21 KKF94852.1 - 6.4e-44 149.6 13.2 7.8e-44 149.3 13.2 1.1 1 0 0 1 1 1 1 Snf7 Mod_r PF07200.13 KKF94852.1 - 0.0026 17.9 6.0 0.0026 17.9 6.0 1.6 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.12 KKF94852.1 - 0.0029 18.0 8.6 0.068 13.7 2.9 2.9 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 KKF94852.1 - 0.013 15.8 6.6 1.8 9.0 0.0 3.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF848 PF05852.11 KKF94852.1 - 0.037 14.1 5.6 0.038 14.1 4.1 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) SNAD3 PF18749.1 KKF94852.1 - 0.04 13.1 0.9 0.047 12.8 0.9 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 Alpha-2-MRAP_C PF06401.11 KKF94852.1 - 0.057 13.4 4.6 0.12 12.4 1.0 2.2 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Endotoxin_N PF03945.14 KKF94852.1 - 0.081 12.6 3.6 0.32 10.7 0.1 2.2 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain DUF4208 PF13907.6 KKF94852.1 - 0.15 12.5 3.1 0.28 11.6 0.7 2.5 1 1 1 3 3 3 0 Domain of unknown function (DUF4208) DUF2205 PF10224.9 KKF94852.1 - 0.21 11.6 6.3 0.13 12.3 1.9 2.6 1 1 1 2 2 2 0 Short coiled-coil protein FlaC_arch PF05377.11 KKF94852.1 - 0.25 11.8 9.5 7 7.1 2.1 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Muted PF14942.6 KKF94852.1 - 1.3 9.4 8.5 1.7 9.0 5.0 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Atg14 PF10186.9 KKF94852.1 - 1.5 7.8 5.7 2.6 7.1 5.6 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 KKF94852.1 - 2 6.3 7.2 3.4 5.5 0.2 1.8 1 1 1 2 2 2 0 Prominin CCDC-167 PF15188.6 KKF94852.1 - 2.2 8.7 5.5 4 7.9 1.1 3.0 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 DUF4446 PF14584.6 KKF94852.1 - 6.6 6.7 7.0 7.4 6.5 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) YabA PF06156.13 KKF94852.1 - 8 7.2 8.6 31 5.3 6.3 2.7 1 1 1 2 2 2 0 Initiation control protein YabA AA_permease PF00324.21 KKF94853.1 - 8.3e-135 450.1 39.9 1e-134 449.7 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKF94853.1 - 2.2e-37 128.9 41.9 3.1e-37 128.4 41.9 1.1 1 0 0 1 1 1 1 Amino acid permease tRNA-synt_1 PF00133.22 KKF94854.1 - 5.3e-37 127.3 0.1 1.1e-28 99.9 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKF94854.1 - 1.6e-11 43.6 0.1 4.5e-07 29.0 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KKF94854.1 - 8.2e-11 42.1 0.1 1.7e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KKF94854.1 - 7.8e-08 32.0 0.0 1.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Clat_adaptor_s PF01217.20 KKF94856.1 - 1.3e-43 148.4 0.0 1.9e-43 147.8 0.0 1.2 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.16 KKF94857.1 - 2.3e-37 127.4 0.0 2.7e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Cyt-b5 PF00173.28 KKF94859.1 - 2.2e-11 43.7 0.0 3.3e-11 43.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Apt1 PF10351.9 KKF94860.1 - 0.13 11.1 1.6 0.12 11.3 1.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cupredoxin_1 PF13473.6 KKF94860.1 - 0.14 12.3 0.0 0.57 10.3 0.0 1.9 1 1 1 2 2 2 0 Cupredoxin-like domain CCDC24 PF15669.5 KKF94860.1 - 2.4 8.0 5.1 4.1 7.2 5.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Macoilin PF09726.9 KKF94860.1 - 2.8 6.4 6.9 3.9 5.9 6.9 1.2 1 0 0 1 1 1 0 Macoilin family CENP-X PF09415.10 KKF94861.1 - 4.6e-23 81.3 0.6 8.4e-23 80.5 0.6 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 KKF94861.1 - 0.007 16.6 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3038 PF11237.8 KKF94861.1 - 0.022 14.8 0.1 0.028 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) Mito_carr PF00153.27 KKF94862.1 - 3.6e-67 222.3 4.7 3.7e-24 84.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 KKF94862.1 - 0.071 12.9 0.8 0.2 11.4 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) UQ_con PF00179.26 KKF94863.1 - 1.7e-36 125.0 0.0 2.3e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1 PF01644.17 KKF94864.1 - 5.8e-69 231.2 0.0 9.6e-69 230.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KKF94864.1 - 2.5e-27 94.6 0.0 4.8e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KKF94864.1 - 1.9e-25 89.5 0.8 5.7e-21 74.7 0.0 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KKF94864.1 - 4.6e-09 36.5 5.6 4.7e-08 33.2 5.6 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Herpes_gE PF02480.16 KKF94865.1 - 0.035 12.9 0.0 0.064 12.0 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Amnionless PF14828.6 KKF94865.1 - 0.066 12.0 0.1 0.093 11.5 0.1 1.2 1 0 0 1 1 1 0 Amnionless Kei1 PF08552.11 KKF94865.1 - 0.27 11.1 2.1 0.3 11.0 0.1 2.0 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Apt1 PF10351.9 KKF94865.1 - 0.27 10.0 3.4 0.08 11.8 0.3 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ras PF00071.22 KKF94866.1 - 9e-51 171.7 0.0 2e-50 170.6 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKF94866.1 - 1.1e-16 61.2 0.0 6.6e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF94866.1 - 0.0005 19.6 0.1 0.0019 17.7 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF2075 PF09848.9 KKF94866.1 - 0.057 12.6 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KKF94866.1 - 0.094 12.3 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KKF94866.1 - 0.12 12.3 0.0 13 5.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KKF94866.1 - 0.14 12.5 0.1 0.26 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M13_N PF05649.13 KKF94867.1 - 1.4e-62 212.6 0.1 2.6e-62 211.7 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KKF94867.1 - 2.6e-21 76.2 0.4 5.1e-21 75.2 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KKF94868.1 - 4.9e-68 230.6 0.0 2.4e-49 169.0 0.1 2.2 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.21 KKF94868.1 - 4e-19 69.0 0.0 1.5e-18 67.2 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M13 FAD_binding_3 PF01494.19 KKF94869.1 - 1.8e-18 66.9 0.0 1.2e-17 64.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKF94869.1 - 1.9e-06 27.3 0.1 0.054 12.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKF94869.1 - 4.5e-05 23.6 1.2 7.9e-05 22.8 0.5 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKF94869.1 - 5.5e-05 22.9 1.7 0.03 13.9 1.3 2.9 1 1 3 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKF94869.1 - 0.023 13.8 0.8 0.065 12.3 0.7 1.7 1 1 1 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KKF94869.1 - 0.11 11.7 0.1 1.2 8.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CYSTM PF12734.7 KKF94870.1 - 3.1e-06 27.4 52.2 0.027 14.8 52.2 3.6 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 KKF94870.1 - 1.4 9.6 5.4 1.5 9.4 5.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 KKF94870.1 - 4.2 7.3 12.1 5.9 6.9 12.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RibD_C PF01872.17 KKF94871.1 - 6.8e-17 62.0 0.0 8.9e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Ccdc124 PF06244.12 KKF94872.1 - 9.5e-20 71.5 25.5 1.8e-18 67.3 25.5 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF3235 PF11574.8 KKF94872.1 - 5 8.1 0.0 5 8.1 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3235) MFS_1 PF07690.16 KKF94873.1 - 2.1e-37 128.9 14.3 3.7e-37 128.1 9.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKF94873.1 - 1.1e-09 37.8 2.1 1.1e-09 37.8 2.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.18 KKF94874.1 - 1e-07 31.3 0.1 5e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain WD40 PF00400.32 KKF94875.1 - 4.5e-13 49.5 1.5 0.04 14.8 0.3 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94875.1 - 0.00015 22.0 0.0 1.7 9.0 0.0 4.3 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain EIF_2_alpha PF07541.12 KKF94876.1 - 2.2e-37 127.7 0.0 4.3e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KKF94876.1 - 1.2e-13 51.2 0.9 2.4e-13 50.2 0.9 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Ribosomal_S30AE PF02482.19 KKF94876.1 - 0.11 13.3 1.5 0.35 11.7 0.1 2.4 2 1 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Mito_carr PF00153.27 KKF94877.1 - 1.7e-62 207.4 3.1 3.7e-21 74.9 0.6 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein SPRY PF00622.28 KKF94878.1 - 0.0078 16.3 0.0 0.69 10.1 0.0 3.0 3 1 0 3 3 3 2 SPRY domain WD40 PF00400.32 KKF94879.1 - 2e-17 63.2 9.4 0.011 16.6 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94879.1 - 0.00013 22.1 0.0 0.59 10.5 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KKF94879.1 - 0.052 13.6 0.0 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DEAD PF00270.29 KKF94880.1 - 1.4e-41 142.2 0.0 2.8e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF94880.1 - 7.5e-22 77.8 0.0 2.9e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KKF94880.1 - 7.8e-05 22.0 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KKF94880.1 - 0.0059 16.6 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KKF94880.1 - 0.038 14.3 0.1 0.16 12.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain INCENP_ARK-bind PF03941.15 KKF94881.1 - 1.8e-19 69.4 2.3 1.8e-19 69.4 2.3 3.6 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region SMC_N PF02463.19 KKF94882.1 - 2.8e-47 161.0 0.0 3e-29 102.0 2.7 2.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKF94882.1 - 3.2e-21 75.8 3.5 1.7e-20 73.5 0.2 3.2 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KKF94882.1 - 0.00033 20.6 0.8 0.0035 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system HSBP1 PF06825.12 KKF94882.1 - 0.76 9.7 11.4 0.027 14.3 1.3 3.9 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Sugarporin_N PF11471.8 KKF94882.1 - 2.6 8.0 14.2 0.062 13.3 1.5 3.9 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension DUF4250 PF14056.6 KKF94882.1 - 3.5 7.6 5.1 5.5 7.0 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4250) cobW PF02492.19 KKF94886.1 - 5.7e-36 123.7 0.6 7.7e-36 123.3 0.6 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KKF94886.1 - 0.028 13.7 0.8 0.31 10.3 0.0 2.2 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 KKF94886.1 - 0.07 13.0 0.6 0.22 11.4 0.1 2.1 2 1 1 3 3 3 0 RsgA GTPase zf-C2H2_2 PF12756.7 KKF94886.1 - 0.12 12.7 0.5 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) NOT2_3_5 PF04153.18 KKF94887.1 - 7.2e-25 87.6 2.7 1.3e-24 86.7 2.7 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Ist1 PF03398.14 KKF94888.1 - 4.2e-60 202.4 0.3 4.2e-60 202.4 0.3 1.7 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway Clat_adaptor_s PF01217.20 KKF94888.1 - 4.7e-48 162.7 1.1 9.9e-48 161.7 1.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TFIID-18kDa PF02269.16 KKF94888.1 - 1.1e-05 25.3 1.0 7.6e-05 22.7 0.2 2.8 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Cadherin_C PF01049.17 KKF94888.1 - 0.022 15.1 1.6 0.046 14.0 1.6 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic region Adaptin_binding PF10199.9 KKF94888.1 - 4.9 7.8 7.7 1.5 9.5 0.9 2.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Glyco_transf_8 PF01501.20 KKF94889.1 - 3.2e-15 56.4 0.0 6e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KKF94889.1 - 0.023 14.1 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative ATG2_CAD PF13329.6 KKF94890.1 - 7.9e-37 126.4 0.1 2e-36 125.1 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KKF94890.1 - 4.2e-31 107.1 0.2 6.7e-30 103.3 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 KKF94890.1 - 0.00057 19.7 0.1 0.0025 17.6 0.1 2.1 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 KKF94890.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal Amino_oxidase PF01593.24 KKF94892.1 - 3.6e-05 23.2 0.1 3.8e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase UCH PF00443.29 KKF94893.1 - 2.4e-44 151.8 0.0 5.2e-44 150.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKF94893.1 - 4.4e-09 36.4 0.1 3.9e-08 33.2 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GH131_N PF18271.1 KKF94894.1 - 3.5e-60 203.8 3.1 4.4e-60 203.5 3.1 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain zf-CCHC PF00098.23 KKF94895.1 - 2.8e-53 175.7 67.0 4e-09 36.1 4.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KKF94895.1 - 3.2e-11 42.8 38.4 0.014 15.1 0.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KKF94895.1 - 4.6e-06 26.2 43.4 0.13 12.0 0.8 7.1 6 1 1 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KKF94895.1 - 6e-06 26.1 50.5 0.16 11.9 0.3 7.1 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.6 KKF94895.1 - 0.01 15.6 10.9 0.024 14.5 2.4 7.2 7 0 0 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.6 KKF94895.1 - 0.21 11.4 47.5 0.63 9.9 1.5 6.7 4 2 3 7 7 7 0 Zinc knuckle Nucleopor_Nup85 PF07575.13 KKF94896.1 - 1.5e-15 56.8 1.3 5.3e-07 28.6 0.1 2.3 2 0 0 2 2 2 2 Nup85 Nucleoporin ADH_N PF08240.12 KKF94897.1 - 4.5e-26 90.9 3.6 1e-25 89.7 3.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKF94897.1 - 7.3e-20 71.3 0.6 1.3e-19 70.4 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KKF94897.1 - 0.00083 19.6 0.1 0.0014 18.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KKF94897.1 - 0.0012 18.2 1.0 0.0022 17.3 1.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KKF94897.1 - 0.0099 15.5 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IGFBP PF00219.18 KKF94897.1 - 0.038 14.7 0.4 0.038 14.7 0.4 1.9 2 0 0 2 2 2 0 Insulin-like growth factor binding protein TrkA_N PF02254.18 KKF94897.1 - 0.039 14.2 0.2 0.1 12.9 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Met_10 PF02475.16 KKF94897.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein zf-AN1 PF01428.16 KKF94898.1 - 2.1e-12 47.0 6.1 2.1e-12 47.0 6.1 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KKF94898.1 - 1.5 9.2 9.0 0.63 10.4 6.7 1.6 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain HhH-GPD PF00730.25 KKF94899.1 - 6.2e-18 65.2 0.0 2.1e-17 63.5 0.0 2.0 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Acyl-CoA_dh_1 PF00441.24 KKF94899.1 - 2.2e-15 57.1 2.3 8.9e-15 55.2 0.4 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HHH PF00633.23 KKF94899.1 - 5.9e-06 25.9 0.0 3.1e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif AidB_N PF18158.1 KKF94899.1 - 0.00034 20.6 0.1 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_2 PF08028.11 KKF94899.1 - 0.0016 18.7 0.0 0.016 15.5 0.0 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain APG5 PF04106.12 KKF94900.1 - 2.8e-44 151.4 0.0 8e-44 149.9 0.0 1.6 1 1 0 1 1 1 1 Autophagy protein Apg5 PKS_DE PF18369.1 KKF94900.1 - 0.035 14.7 2.2 0.65 10.6 0.1 2.8 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain Zn_clus PF00172.18 KKF94901.1 - 3.6e-09 36.6 12.9 5.7e-09 36.0 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YhdB PF14148.6 KKF94901.1 - 0.17 12.0 0.0 0.53 10.4 0.0 1.7 1 1 1 2 2 2 0 YhdB-like protein Spt20 PF12090.8 KKF94901.1 - 6.7 6.2 20.0 14 5.2 20.0 1.5 1 0 0 1 1 1 0 Spt20 family DUF3703 PF12487.8 KKF94902.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) Ribosomal_L22e PF01776.17 KKF94903.1 - 4.2e-43 146.2 0.2 5.2e-43 145.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Mito_carr PF00153.27 KKF94904.1 - 1.4e-55 185.2 0.6 5.2e-18 64.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_A25 PF03418.14 KKF94904.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Germination protease Ribosomal_S4 PF00163.19 KKF94905.1 - 1.1e-10 42.2 0.9 1.7e-10 41.6 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 KKF94905.1 - 3.1e-10 39.6 0.0 7e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain UPF0302 PF08864.10 KKF94905.1 - 0.0032 17.5 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 UPF0302 domain Ribosomal_S18 PF01084.20 KKF94906.1 - 3.2e-10 40.1 0.0 6.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_2 PF13041.6 KKF94907.1 - 1.9e-06 27.9 0.0 0.26 11.5 0.0 4.4 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 KKF94907.1 - 2.8e-05 24.1 0.2 0.53 10.7 0.0 4.4 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 KKF94907.1 - 0.00019 21.4 0.0 0.062 13.4 0.0 3.9 3 1 1 4 4 4 2 Pentatricopeptide repeat domain ATP13 PF12921.7 KKF94907.1 - 0.0033 17.3 0.6 0.26 11.1 0.0 3.0 3 1 0 3 3 3 1 Mitochondrial ATPase expression PPR_long PF17177.4 KKF94907.1 - 0.01 15.2 0.0 0.093 12.1 0.0 2.5 3 1 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KKF94907.1 - 0.017 14.8 0.0 0.83 9.4 0.0 2.5 2 0 0 2 2 2 0 PPR repeat DnaJ_C PF01556.18 KKF94908.1 - 5.8e-27 94.6 0.0 9.6e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKF94908.1 - 1.7e-25 88.9 2.6 3.3e-25 88.0 2.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKF94908.1 - 5.3e-14 52.3 14.7 9e-14 51.6 14.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KKF94908.1 - 7.8e-05 22.6 7.7 0.0076 16.2 2.3 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KKF94908.1 - 0.0021 18.0 7.2 0.076 13.0 0.6 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF5351 PF17302.2 KKF94908.1 - 0.15 12.3 0.5 0.15 12.3 0.5 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF5351) PapD-like PF14874.6 KKF94908.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like zf-C3HC4_3 PF13920.6 KKF94908.1 - 0.21 11.5 9.0 1.3 8.9 0.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 KKF94910.1 - 0.0002 21.2 0.4 0.97 9.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKF94910.1 - 0.0025 17.6 0.6 0.089 12.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKF94910.1 - 0.0058 16.9 0.2 0.018 15.3 0.2 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF94910.1 - 0.018 15.2 0.4 0.033 14.4 0.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KKF94910.1 - 0.074 13.6 0.3 0.18 12.4 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKF94910.1 - 0.88 9.7 3.1 18 5.6 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PLDc PF00614.22 KKF94911.1 - 3.2e-14 52.4 1.6 3.7e-07 30.1 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KKF94911.1 - 5.3e-14 52.3 0.1 2.1e-05 24.4 0.0 4.0 4 1 0 4 4 4 3 PLD-like domain GLTP PF08718.11 KKF94912.1 - 4.3e-44 150.4 0.0 7.9e-44 149.5 0.0 1.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) AAA PF00004.29 KKF94914.1 - 1.6e-50 170.9 0.0 1.8e-40 138.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKF94914.1 - 1e-09 38.0 0.2 7.2e-08 32.1 0.3 2.6 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 KKF94914.1 - 8.9e-05 22.4 0.6 0.26 11.3 0.0 3.7 3 1 0 3 3 3 2 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 KKF94914.1 - 0.00017 21.9 0.0 0.046 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKF94914.1 - 0.00025 21.5 3.3 0.93 9.8 0.1 4.1 2 2 1 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 KKF94914.1 - 0.00051 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KKF94914.1 - 0.00084 19.7 0.0 1.4 9.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.14 KKF94914.1 - 0.0014 18.7 0.0 0.16 12.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KKF94914.1 - 0.018 14.7 0.4 6.7 6.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 KKF94914.1 - 0.021 14.7 0.1 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KKF94914.1 - 0.025 14.7 0.0 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 KKF94914.1 - 0.039 14.2 1.7 18 5.6 0.0 3.6 2 2 2 4 4 4 0 AAA domain GatB_Yqey PF02637.18 KKF94914.1 - 0.071 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 GatB domain AAA_14 PF13173.6 KKF94914.1 - 0.11 12.5 0.0 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fungal_trans_2 PF11951.8 KKF94915.1 - 2.2e-12 46.5 4.1 2e-11 43.4 4.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF979 PF06166.12 KKF94915.1 - 0.025 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF979) Lipocalin_5 PF13924.6 KKF94916.1 - 0.079 12.7 0.2 0.15 11.8 0.2 1.6 1 1 0 1 1 1 0 Lipocalin-like domain R3H-assoc PF13902.6 KKF94917.1 - 1.1e-09 38.7 0.1 1.1e-09 38.7 0.1 2.2 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 KKF94917.1 - 0.0047 16.9 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 R3H domain CCD48 PF15799.5 KKF94917.1 - 0.026 12.8 0.1 0.041 12.2 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 CCDC14 PF15254.6 KKF94918.1 - 0.0013 17.5 1.9 0.0019 16.9 1.9 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 Ion_trans PF00520.31 KKF94919.1 - 6.7e-05 22.2 21.3 0.00011 21.6 21.3 1.3 1 0 0 1 1 1 1 Ion transport protein Croc_4 PF17691.1 KKF94919.1 - 0.61 10.1 5.1 25 4.9 0.0 3.9 4 0 0 4 4 4 0 Contingent replication of cDNA 4 DDHD PF02862.17 KKF94920.1 - 0.8 9.8 4.0 6.4 6.9 1.2 2.3 2 0 0 2 2 2 0 DDHD domain Ntox15 PF15604.6 KKF94920.1 - 3.1 7.9 12.4 0.5 10.5 6.6 2.3 2 0 0 2 2 2 0 Novel toxin 15 BshC PF10079.9 KKF94920.1 - 8.5 5.0 6.7 12 4.5 6.7 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC CPSase_L_D2 PF02786.17 KKF94921.1 - 2.3e-113 376.9 0.5 4.9e-84 281.1 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 KKF94921.1 - 3.7e-47 160.6 0.0 9e-47 159.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KKF94921.1 - 9.4e-47 158.7 0.0 2e-46 157.7 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.22 KKF94921.1 - 5.4e-46 155.6 0.0 1.2e-45 154.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 KKF94921.1 - 1.1e-38 132.4 0.0 2.9e-38 131.0 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KKF94921.1 - 9e-27 94.1 0.0 2.1e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KKF94921.1 - 2.1e-22 79.1 0.0 7.5e-22 77.3 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KKF94921.1 - 4.8e-18 65.4 1.5 7e-08 32.2 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KKF94921.1 - 4.7e-16 58.8 0.2 5.9e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KKF94921.1 - 8.7e-11 41.7 0.0 8e-05 22.4 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KKF94921.1 - 2.5e-06 27.4 0.1 0.00024 21.0 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 KKF94921.1 - 4.9e-05 23.4 0.9 0.23 11.5 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KKF94921.1 - 0.00036 20.4 0.1 0.048 13.5 0.0 3.5 3 0 0 3 3 3 1 DJ-1/PfpI family GARS_A PF01071.19 KKF94921.1 - 0.0012 18.7 0.5 2 8.1 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NACHT PF05729.12 KKF94922.1 - 2.6e-19 69.8 0.0 4.3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AFG1_ATPase PF03969.16 KKF94922.1 - 0.005 15.8 0.0 0.26 10.1 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase TsaE PF02367.17 KKF94922.1 - 0.011 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KKF94922.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3492 PF11997.8 KKF94922.1 - 0.051 13.3 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) TFB6 PF17110.5 KKF94923.1 - 1.4e-33 116.1 0.2 3e-33 115.0 0.2 1.5 1 1 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH VCX_VCY PF15231.6 KKF94923.1 - 0.018 15.8 0.8 0.03 15.0 0.8 1.3 1 0 0 1 1 1 0 Variable charge X/Y family PBP1_TM PF14812.6 KKF94923.1 - 8.3 6.9 9.4 16 5.9 9.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BPL_LplA_LipB PF03099.19 KKF94924.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family LisH PF08513.11 KKF94925.1 - 0.11 12.5 0.2 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 LisH TRAPP PF04051.16 KKF94926.1 - 6.2e-34 116.8 0.0 7.3e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KKF94926.1 - 0.14 10.9 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A WD40 PF00400.32 KKF94927.1 - 9.7e-38 127.5 6.5 2.5e-06 28.1 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94927.1 - 1.7e-10 41.1 0.0 0.019 15.2 0.0 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KKF94927.1 - 0.0011 18.8 1.9 2.8 8.0 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KKF94927.1 - 0.068 12.5 0.0 3.5 6.9 0.0 2.5 2 1 1 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 KKF94927.1 - 0.07 12.1 0.0 5 6.0 0.0 2.8 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Plasmodium_Vir PF05795.11 KKF94928.1 - 0.69 9.3 5.9 0.82 9.0 5.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PEHE PF15275.6 KKF94928.1 - 2.2 8.9 13.1 3.6 8.2 6.0 2.2 1 1 1 2 2 2 0 PEHE domain GREB1 PF15782.5 KKF94928.1 - 5 4.1 8.7 6.1 3.8 8.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-CCHC PF00098.23 KKF94929.1 - 6.5e-46 152.4 63.1 9.9e-09 34.9 2.9 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KKF94929.1 - 2.4e-09 36.8 42.5 0.17 11.7 1.0 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KKF94929.1 - 1.6e-05 24.5 43.7 0.0091 15.7 1.1 6.8 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KKF94929.1 - 0.0027 17.6 41.8 0.076 13.0 0.1 6.8 4 2 2 6 6 6 4 Zinc knuckle FTA4 PF13093.6 KKF94930.1 - 1.1e-39 136.4 0.0 1.3e-38 133.0 0.0 2.0 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PDZ_3 PF17815.1 KKF94930.1 - 0.18 11.6 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 PDZ domain ETRAMP PF09716.10 KKF94931.1 - 0.0068 16.4 0.5 0.027 14.5 0.0 2.0 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) 7TM_GPCR_Sru PF10322.9 KKF94931.1 - 0.064 12.6 0.5 0.088 12.1 0.5 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Cu_bind_like PF02298.17 KKF94931.1 - 0.068 13.2 0.6 0.52 10.4 0.0 2.5 2 1 0 2 2 2 0 Plastocyanin-like domain Orf78 PF06024.12 KKF94931.1 - 0.1 12.9 3.4 0.17 12.2 3.4 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Menin PF05053.13 KKF94931.1 - 0.16 10.3 3.4 0.2 10.0 3.4 1.1 1 0 0 1 1 1 0 Menin UCR_TM PF02921.14 KKF94931.1 - 0.21 12.1 2.6 16 6.0 0.2 2.5 2 1 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region Secretin_N_2 PF07655.13 KKF94931.1 - 0.29 11.7 11.6 0.54 10.8 11.6 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Glyco_hydro_3_C PF01915.22 KKF94932.1 - 6.6e-61 205.8 0.0 1.2e-60 205.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKF94932.1 - 6.3e-44 150.6 0.0 9.9e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKF94932.1 - 1.4e-21 76.4 0.2 2.9e-21 75.3 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KKF94932.1 - 6.8e-12 45.4 0.0 1.5e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 PA14 domain DUF11 PF01345.18 KKF94932.1 - 0.0074 16.6 0.8 0.026 14.8 0.8 2.0 1 0 0 1 1 1 1 Domain of unknown function DUF11 CARDB PF07705.11 KKF94932.1 - 0.022 15.0 0.1 0.051 13.8 0.1 1.5 1 0 0 1 1 1 0 CARDB Phage_tail_X PF05489.12 KKF94932.1 - 0.051 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X PseudoU_synth_2 PF00849.22 KKF94933.1 - 2.7e-30 105.5 0.0 4.1e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.6 KKF94933.1 - 0.019 14.8 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Mut7-C ubiquitin 4HBT PF03061.22 KKF94934.1 - 6.7e-09 36.0 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KKF94934.1 - 5.1e-06 26.0 0.2 9.4e-06 25.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 KKF94934.1 - 2.1e-05 25.0 0.0 2.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MatE PF01554.18 KKF94935.1 - 1.4e-44 151.5 17.5 2.8e-23 82.3 8.8 2.4 2 0 0 2 2 2 2 MatE Patatin PF01734.22 KKF94935.1 - 1.1e-09 38.7 0.1 3.2e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Polysacc_synt_C PF14667.6 KKF94935.1 - 2.3e-07 31.0 2.9 2.3e-07 31.0 2.9 2.7 3 0 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain zf-C2H2 PF00096.26 KKF94936.1 - 6e-05 23.3 12.9 0.074 13.5 1.0 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type Raptor_N PF14538.6 KKF94936.1 - 8.6e-05 22.5 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 KKF94936.1 - 8.8e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Caspase domain zf-C2H2_jaz PF12171.8 KKF94936.1 - 0.041 14.2 2.9 11 6.4 0.6 3.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KKF94936.1 - 0.051 13.7 0.9 1.3 9.1 0.3 2.9 3 0 0 3 3 3 0 Aberrant zinc-finger Sina PF03145.16 KKF94936.1 - 0.052 13.5 1.6 0.11 12.4 1.6 1.5 1 0 0 1 1 1 0 Seven in absentia protein family zf-TRAF PF02176.18 KKF94936.1 - 0.56 10.9 3.0 0.29 11.9 0.4 1.9 2 0 0 2 2 2 0 TRAF-type zinc finger Arrestin_N PF00339.29 KKF94937.1 - 1.3e-12 48.0 0.0 3.2e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain SPX PF03105.19 KKF94937.1 - 1.3 8.8 13.6 1.9 8.3 13.6 1.2 1 0 0 1 1 1 0 SPX domain ORC6 PF05460.13 KKF94937.1 - 1.3 8.2 14.4 2.2 7.5 14.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PT PF04886.12 KKF94937.1 - 5.6 6.6 33.8 1.8 8.1 16.2 2.8 1 1 1 2 2 2 0 PT repeat Sugar_tr PF00083.24 KKF94938.1 - 7.7e-83 278.8 21.6 9.9e-83 278.5 21.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF94938.1 - 2.6e-21 75.9 26.1 2.6e-21 75.9 26.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF676 PF05057.14 KKF94938.1 - 7.9e-06 25.5 1.0 0.0001 21.9 0.0 2.6 2 1 1 3 3 3 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KKF94938.1 - 1e-05 25.4 0.1 1.8e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KKF94938.1 - 0.00022 21.1 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase OATP PF03137.20 KKF94938.1 - 0.00067 18.1 3.8 0.001 17.4 3.8 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Hydrolase_4 PF12146.8 KKF94938.1 - 0.0046 16.2 0.4 0.13 11.5 0.0 2.6 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKF94938.1 - 0.0056 17.3 9.3 0.0056 17.3 9.3 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF900 PF05990.12 KKF94938.1 - 0.011 15.3 0.1 0.029 13.9 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 KKF94938.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 KKF94938.1 - 0.1 12.7 0.1 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain Ser_hydrolase PF06821.13 KKF94938.1 - 0.16 11.9 0.2 0.34 10.8 0.2 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF4208 PF13907.6 KKF94939.1 - 0.083 13.3 2.6 0.9 10.0 1.3 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) RsbU_N PF08673.10 KKF94939.1 - 0.096 12.8 1.2 2.1 8.5 0.3 3.6 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain HALZ PF02183.18 KKF94939.1 - 3.6 7.9 16.4 0.78 10.0 0.5 5.2 5 0 0 5 5 5 0 Homeobox associated leucine zipper FTHFS PF01268.19 KKF94940.1 - 1.3e-251 835.6 0.0 1.8e-251 835.2 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KKF94940.1 - 1.6e-66 222.6 3.3 2.5e-66 221.9 1.4 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KKF94940.1 - 2.9e-27 95.2 0.9 5.7e-27 94.3 0.4 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Helicase_C_4 PF13871.6 KKF94940.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue WD40 PF00400.32 KKF94941.1 - 2.2e-27 94.7 2.6 2.4e-08 34.5 0.1 5.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94941.1 - 4.5e-13 49.3 0.0 0.037 14.3 0.0 4.7 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKF94941.1 - 0.0027 17.6 0.3 0.55 10.1 0.0 3.1 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KKF94941.1 - 0.0084 14.8 0.0 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KKF94941.1 - 0.03 13.3 0.2 4 6.3 0.0 2.9 2 2 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain PQQ PF01011.21 KKF94941.1 - 0.049 13.6 0.4 8.1 6.6 0.0 3.2 3 1 0 3 3 3 0 PQQ enzyme repeat WD40_like PF17005.5 KKF94941.1 - 0.075 12.3 0.0 0.55 9.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Coatomer_WDAD PF04053.14 KKF94941.1 - 0.12 11.4 0.0 0.7 8.9 0.0 2.0 1 1 1 2 2 2 0 Coatomer WD associated region Aminotran_3 PF00202.21 KKF94942.1 - 4e-87 292.5 0.1 4.5e-87 292.3 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KKF94942.1 - 0.0017 17.6 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SNF2_N PF00176.23 KKF94943.1 - 4.3e-73 246.0 0.0 8e-73 245.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KKF94943.1 - 2e-40 137.4 2.1 3.4e-40 136.6 0.6 2.2 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KKF94943.1 - 2.5e-33 115.1 4.8 2.5e-33 115.1 4.8 3.0 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KKF94943.1 - 1.6e-19 70.3 0.0 8.4e-18 64.7 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF94943.1 - 5.2e-09 36.3 0.1 6.4e-08 32.8 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKF94943.1 - 6.4e-06 25.5 0.0 2.4e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KKF94943.1 - 0.0069 16.1 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 KKF94943.1 - 0.01 15.7 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 KKF94943.1 - 0.035 14.3 0.1 8.1 6.7 0.0 3.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain Vir_act_alpha_C PF10400.9 KKF94943.1 - 0.87 10.3 3.7 3.4 8.4 0.4 3.5 3 0 0 3 3 3 0 Virulence activator alpha C-term DUF4588 PF15251.6 KKF94944.1 - 9.4e-07 28.9 0.0 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) MCM PF00493.23 KKF94945.1 - 8e-98 326.0 0.0 1.2e-97 325.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKF94945.1 - 4.3e-38 130.0 0.4 7.6e-38 129.2 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KKF94945.1 - 9.6e-24 84.4 24.1 9.6e-24 84.4 24.1 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KKF94945.1 - 1e-12 48.3 2.6 2.6e-09 37.3 0.3 2.8 1 1 1 2 2 2 2 MCM AAA-lid domain MCM_N PF14551.6 KKF94945.1 - 1.9e-10 41.3 0.2 5e-10 39.9 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKF94945.1 - 7.8e-07 28.7 0.1 4.5e-05 22.9 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKF94945.1 - 2.9e-05 24.1 0.0 6.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKF94945.1 - 0.0034 17.3 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKF94945.1 - 0.043 13.5 0.2 0.26 11.0 0.2 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain zf-UBR PF02207.20 KKF94946.1 - 3.2e-14 52.9 4.8 3.2e-14 52.9 4.8 2.8 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) NAD_kinase PF01513.21 KKF94947.1 - 5e-68 229.4 0.0 6.5e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Aminotran_5 PF00266.19 KKF94950.1 - 9.7e-23 80.7 0.0 1.2e-21 77.1 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V DUF3402 PF11882.8 KKF94952.1 - 7.2e-87 292.4 0.1 7.2e-87 292.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KKF94952.1 - 9.2e-63 212.1 0.0 4.3e-62 209.9 0.0 2.0 1 1 0 1 1 1 1 N1221-like protein DUF2011 PF09428.10 KKF94952.1 - 7e-24 83.9 0.0 2.3e-23 82.3 0.0 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Ribosomal_S14 PF00253.21 KKF94952.1 - 8.5e-13 47.9 4.7 1.6e-12 47.0 4.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e TAF4 PF05236.14 KKF94952.1 - 0.00059 19.7 9.1 0.0014 18.5 9.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family POP1 PF06978.11 KKF94952.1 - 0.47 10.4 16.1 0.99 9.4 16.1 1.4 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 OAD_gamma PF04277.13 KKF94952.1 - 5.4 7.7 7.5 36 5.1 7.5 2.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain NDT80_PhoG PF05224.12 KKF94953.1 - 3.5e-34 118.6 0.0 5.8e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family GMC_oxred_C PF05199.13 KKF94954.1 - 2.2e-07 31.5 0.1 8.1e-07 29.7 0.1 2.0 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KKF94954.1 - 2.1e-06 27.3 0.0 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase SIT PF15330.6 KKF94955.1 - 0.036 14.5 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT WD40 PF00400.32 KKF94956.1 - 5e-110 356.3 60.0 2.9e-11 43.7 2.3 11.5 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94956.1 - 2e-45 153.0 19.7 3.9e-06 27.1 0.0 10.6 2 2 8 10 10 10 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF94956.1 - 5.7e-16 58.4 22.7 7.3e-05 21.9 1.2 8.4 1 1 7 8 8 8 7 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KKF94956.1 - 7.6e-11 41.7 0.0 32 4.6 0.0 8.4 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Patatin PF01734.22 KKF94956.1 - 2e-08 34.7 0.0 5.8e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase NACHT PF05729.12 KKF94956.1 - 1.6e-07 31.4 0.0 3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 KKF94956.1 - 1.3e-05 24.1 21.8 1.7 7.2 0.1 8.7 2 2 8 10 10 10 5 Nucleoporin Nup120/160 AAA_19 PF13245.6 KKF94956.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF1986 PF09342.11 KKF94956.1 - 2.6 8.5 6.9 65 3.9 0.1 5.1 6 0 0 6 6 6 0 Domain of unknown function (DUF1986) NACHT PF05729.12 KKF94957.1 - 3.8e-07 30.2 0.0 5.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KKF94957.1 - 0.049 14.0 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KKF94957.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KKF94957.1 - 0.17 12.3 0.0 0.46 10.9 0.0 1.7 2 0 0 2 2 2 0 RNA helicase ELFV_dehydrog PF00208.21 KKF94958.1 - 4.9e-84 281.9 5.2 6e-84 281.6 5.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KKF94958.1 - 4.4e-51 172.2 0.0 8.2e-51 171.3 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 KKF94958.1 - 0.03 14.8 0.1 0.077 13.4 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Thioredoxin PF00085.20 KKF94959.1 - 1.2e-55 185.8 0.0 2.7e-29 101.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KKF94959.1 - 1.5e-23 83.5 1.6 1.5e-23 83.5 1.6 2.5 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KKF94959.1 - 1.8e-16 60.5 0.0 6.1e-08 33.1 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KKF94959.1 - 1.6e-11 44.1 0.0 9.1e-05 21.9 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KKF94959.1 - 1.5e-09 38.1 0.0 0.0002 21.6 0.0 3.5 2 2 2 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 KKF94959.1 - 8.2e-08 32.2 0.1 0.016 15.1 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 KKF94959.1 - 1.2e-06 28.6 0.0 0.11 12.7 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 KKF94959.1 - 9.5e-05 22.1 0.3 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 Redoxin LEA_4 PF02987.16 KKF94959.1 - 0.0011 19.0 18.0 0.004 17.2 18.0 1.9 1 0 0 1 1 1 1 Late embryogenesis abundant protein TraF PF13728.6 KKF94959.1 - 0.0038 17.1 1.0 0.19 11.5 0.0 3.2 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KKF94959.1 - 0.012 15.4 0.0 8.3 6.2 0.1 2.7 2 0 0 2 2 2 0 Thioredoxin HyaE PF07449.11 KKF94959.1 - 0.046 13.7 0.0 0.97 9.4 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DltD PF04914.12 KKF94959.1 - 0.94 8.8 7.1 1.5 8.1 7.1 1.2 1 0 0 1 1 1 0 DltD protein DUF883 PF05957.13 KKF94959.1 - 5.1 7.8 12.0 21 5.8 4.6 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-rbx1 PF12678.7 KKF94960.1 - 3.9e-10 39.9 0.4 7.4e-10 39.0 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KKF94960.1 - 1e-07 32.2 7.5 8.8e-07 29.2 7.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KKF94960.1 - 3.7e-07 30.1 0.0 1.3e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KKF94960.1 - 3.9e-07 29.8 0.3 6.8e-07 29.0 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKF94960.1 - 3.6e-06 26.7 5.4 4.4e-06 26.4 1.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKF94960.1 - 1.2e-05 25.2 0.4 2.2e-05 24.3 0.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KKF94960.1 - 0.00074 19.2 4.5 0.003 17.3 0.5 2.5 2 0 0 2 2 2 1 RING-like zinc finger PQ-loop PF04193.14 KKF94960.1 - 0.0014 18.4 0.3 0.0049 16.6 0.3 2.0 1 0 0 1 1 1 1 PQ loop repeat Prok-RING_4 PF14447.6 KKF94960.1 - 0.0023 17.7 0.9 0.0052 16.6 0.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KKF94960.1 - 0.0024 17.7 0.6 0.0024 17.7 0.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KKF94960.1 - 0.02 14.5 0.5 0.02 14.5 0.5 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type COX14 PF14880.6 KKF94960.1 - 0.041 13.7 0.1 0.59 10.0 0.1 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly zf-ANAPC11 PF12861.7 KKF94960.1 - 0.16 12.0 0.5 0.43 10.7 0.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger WD40 PF00400.32 KKF94961.1 - 2.5e-19 69.2 2.2 0.00011 22.9 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF94961.1 - 1.4e-15 57.3 0.3 1.3e-05 25.4 0.0 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKF94961.1 - 1.2e-05 25.3 0.0 0.0037 17.2 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KKF94961.1 - 0.0014 17.8 0.2 0.015 14.3 0.1 2.1 1 1 1 2 2 2 1 Coatomer WD associated region IKI3 PF04762.12 KKF94961.1 - 0.0033 15.5 0.4 0.23 9.4 0.1 1.7 1 1 1 2 2 2 2 IKI3 family WD40_like PF17005.5 KKF94961.1 - 0.024 14.0 0.0 0.058 12.7 0.1 1.7 2 1 0 2 2 2 0 WD40-like domain MMS1_N PF10433.9 KKF94961.1 - 0.035 12.8 0.0 0.087 11.4 0.0 1.6 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PD40 PF07676.12 KKF94961.1 - 0.052 13.5 0.2 0.58 10.2 0.2 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat RasGAP_C PF03836.15 KKF94962.1 - 5e-48 162.7 6.2 5e-48 162.7 6.2 2.4 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 KKF94962.1 - 1.7e-47 161.8 0.0 6e-47 160.1 0.0 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 KKF94962.1 - 9.2e-15 53.0 54.6 0.23 11.3 0.2 14.9 16 0 0 16 16 16 8 IQ calmodulin-binding motif CH PF00307.31 KKF94962.1 - 1.5e-10 41.2 0.0 5.7e-10 39.3 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain RNase_J_C PF17770.1 KKF94962.1 - 0.047 14.7 0.2 1.9 9.6 0.0 3.7 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain Sulfatase PF00884.23 KKF94963.1 - 1.1e-53 182.6 0.3 1.6e-53 182.1 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KKF94963.1 - 1.7e-25 88.6 4.5 3.1e-25 87.7 1.5 2.5 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KKF94963.1 - 3e-09 36.9 0.1 0.00015 21.5 0.0 2.5 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KKF94963.1 - 0.0052 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KKF94963.1 - 0.061 11.9 0.0 0.086 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) GCP5-Mod21 PF14609.6 KKF94963.1 - 0.12 10.7 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Med8 PF10232.9 KKF94964.1 - 3.2e-17 62.9 0.2 4e-17 62.6 0.2 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Acyl_transf_3 PF01757.22 KKF94965.1 - 1.4e-08 34.2 0.5 1.8e-08 33.8 0.5 1.2 1 0 0 1 1 1 1 Acyltransferase family RNase_P_p30 PF01876.16 KKF94966.1 - 1.8e-45 155.1 0.0 2.6e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 DUF155 PF02582.14 KKF94967.1 - 1.3e-53 181.7 0.0 2.2e-53 181.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ECSCR PF15820.5 KKF94967.1 - 0.078 12.8 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator LBP_BPI_CETP_C PF02886.17 KKF94967.1 - 0.11 11.9 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain Insulin_TMD PF17870.1 KKF94967.1 - 0.19 11.8 2.0 0.4 10.8 2.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment E1-E2_ATPase PF00122.20 KKF94968.1 - 4.3e-50 169.7 0.1 4.3e-50 169.7 0.1 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKF94968.1 - 2.3e-36 126.1 1.8 2.3e-36 126.1 1.8 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KKF94968.1 - 4.7e-30 103.8 6.6 1.1e-11 45.0 0.5 4.4 4 0 0 4 4 4 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KKF94968.1 - 2.3e-05 24.3 0.5 6.2e-05 22.9 0.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L31e PF01198.19 KKF94969.1 - 6.6e-38 128.8 0.5 8.5e-38 128.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.26 KKF94970.1 - 1.7e-47 160.6 0.0 1.9e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKF94970.1 - 1.9e-05 24.4 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KKF94970.1 - 0.012 15.9 0.1 0.018 15.4 0.1 1.4 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 KKF94970.1 - 0.084 12.7 0.1 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 UEV domain Pkinase PF00069.25 KKF94971.1 - 4.3e-54 183.6 0.0 6.3e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF94971.1 - 2.9e-26 92.3 0.0 4.5e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF94971.1 - 0.0041 16.5 0.0 0.01 15.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKF94971.1 - 0.0096 14.7 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KKF94971.1 - 0.02 14.8 0.0 0.12 12.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KKF94971.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKF94971.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase LigB PF02900.18 KKF94973.1 - 5.1e-34 117.6 0.0 6.1e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DNA_ligase_A_M PF01068.21 KKF94974.1 - 3.5e-47 160.7 0.1 6.2e-47 159.9 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKF94974.1 - 3.9e-34 118.5 0.0 1.2e-33 116.8 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus RNA_ligase PF09414.10 KKF94974.1 - 1.7e-16 60.9 0.0 3.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 KKF94974.1 - 2.4e-13 50.5 0.0 8.3e-13 48.8 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 KKF94974.1 - 4.2e-12 46.3 0.0 5.5e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KKF94974.1 - 1.2e-09 38.4 0.0 4.1e-07 30.3 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.19 KKF94974.1 - 4.6e-06 26.6 0.1 0.018 14.9 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain DNA_ligase_IV PF11411.8 KKF94974.1 - 2.8e-05 24.1 2.6 0.00025 21.1 0.0 3.1 3 0 0 3 3 3 1 DNA ligase IV LIG3_BRCT PF16759.5 KKF94974.1 - 0.00034 20.9 0.0 0.12 12.7 0.1 2.6 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain DUF4315 PF14193.6 KKF94974.1 - 0.83 9.7 3.1 1.4 9.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) DUF4449 PF14613.6 KKF94975.1 - 5e-29 101.5 0.5 5e-29 101.5 0.5 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) CRCB PF02537.15 KKF94975.1 - 3e-12 46.7 0.0 1.3e-11 44.7 0.0 2.0 1 1 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) Meiotic_rec114 PF03525.14 KKF94976.1 - 0.061 12.3 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Meiotic recombination protein rec114 Ribosomal_S19e PF01090.19 KKF94977.1 - 1e-57 193.7 0.1 1.2e-57 193.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DEAD PF00270.29 KKF94978.1 - 2.7e-47 160.8 0.0 5.1e-47 159.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF94978.1 - 1.5e-30 105.8 0.1 6.5e-30 103.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF913 PF06025.12 KKF94978.1 - 1.7 7.5 9.1 38 3.1 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Zip PF02535.22 KKF94979.1 - 1.8e-63 214.8 8.1 2e-63 214.7 8.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Curto_V3 PF07436.11 KKF94979.1 - 0.076 13.4 0.4 0.22 11.9 0.1 1.9 2 0 0 2 2 2 0 Curtovirus V3 protein zf-rbx1 PF12678.7 KKF94980.1 - 1.2e-08 35.1 5.1 2.2e-08 34.3 5.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KKF94980.1 - 1.4e-08 34.9 9.7 2.3e-08 34.3 9.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KKF94980.1 - 3.6e-05 23.7 4.9 6.4e-05 22.9 4.9 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KKF94980.1 - 0.002 18.0 3.9 0.17 11.8 1.2 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KKF94980.1 - 0.0021 17.9 6.2 0.0034 17.2 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KKF94980.1 - 0.004 17.2 5.8 0.015 15.4 5.8 1.9 1 1 0 1 1 1 1 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 KKF94980.1 - 0.0047 16.7 8.8 0.01 15.7 8.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKF94980.1 - 0.0099 15.9 5.7 0.013 15.5 3.8 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Rad50_zn_hook PF04423.14 KKF94980.1 - 0.01 15.6 1.8 0.053 13.4 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4 PF00097.25 KKF94980.1 - 0.094 12.6 8.0 0.16 11.9 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.15 KKF94980.1 - 0.17 11.5 2.1 0.28 10.8 0.1 2.2 2 0 0 2 2 2 0 RecR protein zf-Di19 PF05605.12 KKF94980.1 - 0.28 11.5 4.9 18 5.7 2.4 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 KKF94980.1 - 0.46 10.3 6.2 1.3 8.8 6.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KKF94980.1 - 3.3 7.6 8.1 3 7.7 5.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger PEMT PF04191.13 KKF94981.1 - 3.3e-32 111.0 3.8 3.3e-32 111.0 3.8 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase Thiolase_N PF00108.23 KKF94982.1 - 2.8e-70 236.6 5.6 4.7e-70 235.9 5.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKF94982.1 - 1.2e-42 144.5 0.1 2.6e-42 143.3 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain Trns_repr_metal PF02583.17 KKF94982.1 - 0.022 15.1 0.2 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor ACP_syn_III_C PF08541.10 KKF94982.1 - 0.072 13.3 0.0 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Aim21 PF11489.8 KKF94983.1 - 1.2e-91 308.8 72.5 4.8e-68 230.7 59.2 3.2 2 1 1 3 3 3 2 Altered inheritance of mitochondria protein 21 Cg6151-P PF10233.9 KKF94984.1 - 5.1e-41 139.5 13.4 6.1e-41 139.3 13.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 KKF94984.1 - 0.26 11.3 13.7 1.1 9.3 13.2 1.8 1 1 1 2 2 2 0 COPI associated protein OCD_Mu_crystall PF02423.15 KKF94985.1 - 2.7e-11 43.0 0.4 1.4e-05 24.2 0.0 2.9 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Corona_nucleoca PF00937.18 KKF94985.1 - 0.3 10.1 2.0 0.48 9.4 2.0 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Ribosomal_L20 PF00453.18 KKF94986.1 - 0.39 10.8 3.6 1 9.5 3.6 1.7 1 0 0 1 1 1 0 Ribosomal protein L20 Dna2 PF08696.11 KKF94987.1 - 1.1e-59 201.7 0.0 2.1e-59 200.8 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KKF94987.1 - 1.6e-52 178.0 0.0 2.8e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKF94987.1 - 9.9e-33 114.0 0.4 1.4e-16 61.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KKF94987.1 - 3.9e-15 56.1 0.0 9.6e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF94987.1 - 6.8e-12 45.9 0.0 1.7e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KKF94987.1 - 3.4e-09 37.0 0.0 1.4e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KKF94987.1 - 1.1e-07 31.9 0.2 0.051 13.3 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KKF94987.1 - 0.00012 22.0 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KKF94987.1 - 0.00037 20.1 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 KKF94987.1 - 0.00043 20.0 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KKF94987.1 - 0.00058 19.4 0.0 0.0028 17.2 0.1 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region PIF1 PF05970.14 KKF94987.1 - 0.00065 19.0 0.1 0.0036 16.5 0.1 1.9 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KKF94987.1 - 0.003 17.9 0.0 0.012 16.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KKF94987.1 - 0.023 14.8 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 KKF94987.1 - 0.026 14.1 0.1 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KKF94987.1 - 0.031 14.4 0.1 0.078 13.1 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_5 PF07728.14 KKF94987.1 - 0.032 14.2 0.1 0.091 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KKF94987.1 - 0.041 13.1 0.0 0.097 11.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 KKF94987.1 - 0.043 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KKF94987.1 - 0.078 13.0 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit cobW PF02492.19 KKF94987.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KKF94987.1 - 0.14 12.3 0.0 0.45 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKF94987.1 - 0.15 12.4 0.0 0.47 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KKF94987.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ESSS PF10183.9 KKF94988.1 - 1.9e-09 37.7 0.0 2.1e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aminotran_4 PF01063.19 KKF94989.1 - 3.9e-32 111.9 0.0 5.7e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV WD40 PF00400.32 KKF94990.1 - 8.1e-85 276.5 32.6 7e-12 45.7 0.7 9.7 9 0 0 9 9 9 8 WD domain, G-beta repeat NACHT_N PF17100.5 KKF94990.1 - 2.7e-70 236.7 1.3 2.7e-70 236.7 1.3 2.6 3 0 0 3 3 3 1 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 KKF94990.1 - 1.2e-29 102.5 10.2 0.00024 21.3 0.0 8.5 1 1 7 8 8 8 8 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KKF94990.1 - 2.8e-17 63.1 0.0 7.9e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KKF94990.1 - 1.3e-14 53.9 11.9 0.002 17.1 0.4 6.2 1 1 5 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KKF94990.1 - 1.1e-06 27.4 8.0 0.025 13.1 0.2 4.0 2 2 1 3 3 3 3 Cytochrome D1 heme domain WD40_like PF17005.5 KKF94990.1 - 1.8e-05 24.2 0.1 3.6 6.8 0.0 4.2 3 1 0 4 4 4 3 WD40-like domain Nup160 PF11715.8 KKF94990.1 - 4.7e-05 22.2 19.8 0.83 8.2 0.1 7.1 2 2 5 7 7 7 3 Nucleoporin Nup120/160 Frtz PF11768.8 KKF94990.1 - 0.00078 17.9 0.5 4.9 5.3 0.1 4.1 1 1 2 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz CDtoxinA PF03498.14 KKF94990.1 - 0.0025 17.4 1.1 10 5.7 0.0 4.1 1 1 1 3 3 3 1 Cytolethal distending toxin A/C domain AAA_16 PF13191.6 KKF94990.1 - 0.0034 17.8 0.0 0.021 15.2 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.12 KKF94990.1 - 0.044 13.7 0.0 74 3.5 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Robl_LC7 PF03259.17 KKF94990.1 - 0.062 13.1 0.4 9.4 6.1 0.0 3.8 3 2 1 4 4 4 0 Roadblock/LC7 domain DASH_Dad2 PF08654.10 KKF94990.1 - 0.22 12.0 3.7 0.4 11.1 1.9 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad2 Peptidase_S49_N PF08496.10 KKF94990.1 - 0.91 9.6 4.8 3 7.9 4.8 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NACHT PF05729.12 KKF94991.1 - 1.7e-20 73.6 0.0 3.6e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Patatin PF01734.22 KKF94991.1 - 2.5e-13 50.7 0.0 1.1e-12 48.6 0.0 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase AAA_22 PF13401.6 KKF94991.1 - 0.0027 18.0 0.0 0.0064 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF94991.1 - 0.0057 17.0 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKF94991.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKF94991.1 - 0.046 14.1 0.2 0.26 11.7 0.2 2.3 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KKF94991.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_23 PF18009.1 KKF94991.1 - 0.37 11.2 2.7 4.4 7.8 2.7 2.4 1 1 0 1 1 1 0 4Fe-4S iron-sulfur cluster binding domain Ferric_reduct PF01794.19 KKF94992.1 - 5e-21 75.1 10.4 5e-21 75.1 10.4 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KKF94992.1 - 4.6e-16 59.3 0.0 7.1e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKF94992.1 - 7.6e-09 35.6 0.0 3.2e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KKF94992.1 - 3.3e-05 24.5 0.0 9.4e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain ADH_zinc_N_2 PF13602.6 KKF94993.1 - 2e-17 64.5 0.0 3.8e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKF94993.1 - 1.1e-15 57.8 0.2 2.2e-15 56.8 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase N-SET PF11764.8 KKF94994.1 - 3.2e-52 177.1 1.0 3.2e-52 177.1 1.0 3.1 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 KKF94994.1 - 2.4e-19 70.3 0.1 2.4e-19 70.3 0.1 4.4 2 2 0 2 2 2 1 SET domain SET_assoc PF11767.8 KKF94994.1 - 1.5e-10 40.5 3.3 7.3e-10 38.3 1.3 2.8 2 1 1 3 3 3 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.22 KKF94994.1 - 0.0035 17.1 0.4 0.1 12.4 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tombus_movement PF05318.12 KKF94994.1 - 1.4 9.8 4.8 7 7.6 4.8 2.2 1 0 0 1 1 1 0 Tombusvirus movement protein Tropomyosin_1 PF12718.7 KKF94996.1 - 6.1e-54 182.1 32.8 7.1e-54 181.8 32.8 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KKF94996.1 - 3.6e-07 29.8 32.9 4.7e-05 22.9 20.6 2.9 1 1 1 2 2 2 2 Tropomyosin ATG16 PF08614.11 KKF94996.1 - 0.00057 20.2 30.3 0.72 10.0 18.7 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 KKF94996.1 - 0.0014 19.0 19.7 0.025 15.0 3.9 4.2 3 1 1 4 4 4 1 Flagella accessory protein C (FlaC) DUF724 PF05266.14 KKF94996.1 - 0.0015 18.4 22.8 0.018 14.9 7.9 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF724) Spc7 PF08317.11 KKF94996.1 - 0.0023 16.8 31.4 0.0029 16.5 17.7 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein GAS PF13851.6 KKF94996.1 - 0.0024 17.3 31.4 0.024 14.0 18.7 2.1 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 KKF94996.1 - 0.0041 17.3 20.4 0.0097 16.1 4.8 3.0 1 1 2 3 3 3 2 Predicted coiled-coil domain-containing protein Syntaxin-6_N PF09177.11 KKF94996.1 - 0.0048 17.4 16.6 0.48 11.0 8.5 2.8 1 1 1 2 2 2 2 Syntaxin 6, N-terminal Uso1_p115_C PF04871.13 KKF94996.1 - 0.0052 17.1 33.5 0.25 11.7 14.9 2.1 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 KKF94996.1 - 0.0052 16.8 33.0 0.019 15.0 4.2 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KKF94996.1 - 0.0054 16.8 26.3 0.054 13.6 6.4 3.1 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 KKF94996.1 - 0.011 15.0 27.2 0.048 12.8 13.7 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Alanine_zipper PF11839.8 KKF94996.1 - 0.011 16.0 6.8 0.026 14.9 0.2 3.1 1 1 3 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein DUF4200 PF13863.6 KKF94996.1 - 0.014 15.7 31.4 0.38 11.1 14.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 KKF94996.1 - 0.018 14.4 24.6 0.14 11.5 10.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KKF94996.1 - 0.019 15.5 38.3 1.5 9.4 16.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 KKF94996.1 - 0.021 15.3 24.3 0.035 14.6 24.3 1.3 1 0 0 1 1 1 0 Fez1 DUF1664 PF07889.12 KKF94996.1 - 0.027 14.5 16.5 0.2 11.7 4.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HOOK PF05622.12 KKF94996.1 - 0.027 12.6 26.7 0.038 12.1 26.7 1.2 1 0 0 1 1 1 0 HOOK protein Lebercilin PF15619.6 KKF94996.1 - 0.029 14.0 32.7 0.12 12.0 12.5 2.3 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.8 KKF94996.1 - 0.031 14.5 26.2 0.21 11.8 17.8 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 KKF94996.1 - 0.044 13.8 18.0 0.064 13.3 3.7 2.8 1 1 1 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 KKF94996.1 - 0.045 14.0 20.9 7.1 7.0 0.6 3.7 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TACC_C PF05010.14 KKF94996.1 - 0.047 13.5 23.2 0.45 10.3 12.7 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DivIC PF04977.15 KKF94996.1 - 0.049 13.4 1.1 0.049 13.4 1.1 4.3 1 1 3 4 4 4 0 Septum formation initiator CALCOCO1 PF07888.11 KKF94996.1 - 0.059 12.2 30.2 1.4 7.7 20.7 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-K PF11802.8 KKF94996.1 - 0.07 12.7 18.9 0.57 9.7 4.8 2.1 1 1 1 2 2 2 0 Centromere-associated protein K Jnk-SapK_ap_N PF09744.9 KKF94996.1 - 0.083 13.1 32.0 0.061 13.5 19.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HMMR_C PF15908.5 KKF94996.1 - 0.088 13.1 17.8 0.28 11.5 3.7 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal ERM PF00769.19 KKF94996.1 - 0.096 12.5 34.4 0.16 11.8 15.7 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HMMR_N PF15905.5 KKF94996.1 - 0.12 11.8 27.2 0.19 11.2 27.2 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Seryl_tRNA_N PF02403.22 KKF94996.1 - 0.13 12.5 26.1 0.96 9.7 0.3 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF5082 PF16888.5 KKF94996.1 - 0.17 12.2 19.3 20 5.5 6.2 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) Filament PF00038.21 KKF94996.1 - 0.2 11.2 25.6 0.31 10.6 25.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein Fmp27_WPPW PF10359.9 KKF94996.1 - 0.21 10.4 22.1 0.052 12.4 8.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain EzrA PF06160.12 KKF94996.1 - 0.22 9.7 21.6 0.77 7.9 18.8 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA bZIP_1 PF00170.21 KKF94996.1 - 0.22 11.6 29.4 0.43 10.7 1.2 4.8 1 1 3 4 4 4 0 bZIP transcription factor KASH_CCD PF14662.6 KKF94996.1 - 0.25 11.1 30.5 0.44 10.4 27.5 2.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 KKF94996.1 - 0.29 10.9 22.1 2.1 8.0 11.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) BRE1 PF08647.11 KKF94996.1 - 0.31 11.2 29.3 1.1 9.3 15.1 2.8 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase KxDL PF10241.9 KKF94996.1 - 0.31 11.3 16.8 1 9.7 0.2 3.7 1 1 2 3 3 3 0 Uncharacterized conserved protein HrpB7 PF09486.10 KKF94996.1 - 0.34 11.3 18.4 0.49 10.8 3.7 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF812 PF05667.11 KKF94996.1 - 0.34 9.7 25.2 0.59 8.9 25.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) WXG100 PF06013.12 KKF94996.1 - 0.36 11.1 13.6 2.8 8.2 3.4 3.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Cep57_MT_bd PF06657.13 KKF94996.1 - 0.42 11.1 22.7 0.18 12.3 3.8 3.5 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 UPF0242 PF06785.11 KKF94996.1 - 0.42 10.7 29.7 0.65 10.1 10.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 KKF94996.1 - 0.6 10.3 14.0 4.1 7.6 4.0 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KKF94996.1 - 0.67 10.5 9.6 13 6.3 2.8 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.8 KKF94996.1 - 0.72 9.9 33.3 1.1 9.3 11.9 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Syntaxin_2 PF14523.6 KKF94996.1 - 0.88 10.0 17.3 0.51 10.7 7.9 2.2 1 1 1 2 2 2 0 Syntaxin-like protein SOGA PF11365.8 KKF94996.1 - 1.1 10.5 22.5 53 5.0 16.1 3.6 1 1 1 2 2 2 0 Protein SOGA FUSC PF04632.12 KKF94996.1 - 1.1 7.7 7.2 1.2 7.5 7.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cortex-I_coil PF09304.10 KKF94996.1 - 1.2 9.4 23.6 8.1 6.7 8.5 3.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil TPR_MLP1_2 PF07926.12 KKF94996.1 - 1.2 9.2 35.2 0.55 10.3 10.0 3.0 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein MAD PF05557.13 KKF94996.1 - 1.3 7.3 27.6 2.4 6.4 27.6 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein FapA PF03961.13 KKF94996.1 - 1.4 7.4 23.7 1.2 7.6 7.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A ZapB PF06005.12 KKF94996.1 - 1.5 9.3 35.4 23 5.5 16.8 4.0 1 1 2 3 3 3 0 Cell division protein ZapB Atg14 PF10186.9 KKF94996.1 - 1.6 7.8 20.7 1.5 7.8 14.5 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 KKF94996.1 - 1.7 9.3 25.6 0.93 10.1 4.2 3.4 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Sec34 PF04136.15 KKF94996.1 - 2 8.3 16.4 1.2 9.0 4.1 2.6 1 1 2 3 3 3 0 Sec34-like family DUF2203 PF09969.9 KKF94996.1 - 2 9.2 18.2 4.4 8.0 4.9 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) XhlA PF10779.9 KKF94996.1 - 2.2 8.5 24.4 4.5 7.5 2.5 4.3 1 1 3 4 4 4 0 Haemolysin XhlA Rootletin PF15035.6 KKF94996.1 - 2.5 8.1 27.1 0.47 10.5 8.0 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion AAA_13 PF13166.6 KKF94996.1 - 2.6 6.6 21.6 29 3.1 21.6 2.0 1 1 0 1 1 1 0 AAA domain DHR10 PF18595.1 KKF94996.1 - 2.7 8.1 34.3 0.22 11.6 11.5 2.9 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain SlyX PF04102.12 KKF94996.1 - 4.2 8.1 22.7 0.95 10.1 3.4 3.8 1 1 2 4 4 4 0 SlyX FAM76 PF16046.5 KKF94996.1 - 4.2 6.6 20.8 0.86 8.9 11.5 2.0 1 1 1 2 2 2 0 FAM76 protein Ax_dynein_light PF10211.9 KKF94996.1 - 4.2 7.3 30.4 8.2 6.3 5.2 3.6 1 1 2 3 3 3 0 Axonemal dynein light chain CHDCT2 PF08074.11 KKF94996.1 - 4.6 7.4 11.7 1.2 9.3 4.1 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF948 PF06103.11 KKF94996.1 - 4.9 7.5 11.4 32 4.8 3.4 3.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Cep57_CLD_2 PF14197.6 KKF94996.1 - 5.1 7.3 26.9 17 5.6 3.8 4.2 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 DUF3584 PF12128.8 KKF94996.1 - 5.1 4.5 26.5 8.4 3.8 26.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF745 PF05335.13 KKF94996.1 - 5.4 6.7 19.8 0.25 11.0 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) LPP PF04728.13 KKF94996.1 - 5.7 7.4 14.4 5.2 7.5 0.2 4.3 3 1 1 4 4 4 0 Lipoprotein leucine-zipper V_ATPase_I PF01496.19 KKF94996.1 - 5.8 4.7 17.7 12 3.7 17.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family HAP1_N PF04849.13 KKF94996.1 - 7.8 5.6 28.7 51 2.9 28.7 2.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF2730 PF10805.8 KKF94996.1 - 8 6.6 13.0 1.8 8.7 4.3 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) TFR_dimer PF04253.15 KKF94996.1 - 8.2 6.6 14.3 0.82 9.8 2.7 3.0 2 1 1 3 3 3 0 Transferrin receptor-like dimerisation domain YabA PF06156.13 KKF94996.1 - 8.5 7.1 22.1 1.7e+02 2.9 4.2 3.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF4795 PF16043.5 KKF94996.1 - 8.8 5.9 25.3 55 3.3 25.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4407 PF14362.6 KKF94996.1 - 9.7 5.4 20.4 18 4.5 20.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Nop25 PF09805.9 KKF94997.1 - 9.6e-36 123.3 12.9 9.6e-36 123.3 12.9 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) VEFS-Box PF09733.9 KKF94997.1 - 0.056 13.3 4.0 0.13 12.1 4.0 1.6 1 0 0 1 1 1 0 VEFS-Box of polycomb protein ATP-synt_S1 PF05827.12 KKF94998.1 - 0.006 16.4 0.6 0.0096 15.8 0.6 1.5 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Sensor_TM1 PF13755.6 KKF94998.1 - 0.14 11.9 0.1 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain Trm112p PF03966.16 KKF94999.1 - 5.5e-14 52.5 0.2 7e-14 52.1 0.2 1.2 1 0 0 1 1 1 1 Trm112p-like protein Pro_isomerase PF00160.21 KKF95000.1 - 2e-46 158.1 0.3 2.9e-46 157.6 0.3 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 KKF95001.1 - 1.1e-16 61.4 1.1 1.1e-14 54.9 1.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_M19 PF01244.21 KKF95002.1 - 1.7e-103 346.1 0.0 2e-103 345.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DEP PF00610.21 KKF95003.1 - 9.9e-14 51.2 0.0 2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 KKF95003.1 - 1.6e-13 50.8 0.1 4.4e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KKF95003.1 - 1.6e-10 41.1 0.0 4.3e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.18 KKF95003.1 - 0.014 15.1 0.3 0.033 13.9 0.3 1.6 1 0 0 1 1 1 0 BAR domain Phage_TAC_8 PF10666.9 KKF95003.1 - 0.018 15.3 0.1 0.048 13.9 0.1 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 Polyketide_cyc PF03364.20 KKF95004.1 - 2.6e-20 73.0 0.0 3.3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KKF95004.1 - 0.0045 17.3 0.3 0.037 14.3 0.2 2.4 1 1 1 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport TPR_14 PF13428.6 KKF95006.1 - 1.2e-10 41.3 5.9 0.00058 20.5 0.4 4.9 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKF95006.1 - 7.4e-10 39.2 1.9 6.4e-05 23.4 0.0 3.7 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKF95006.1 - 1.6e-09 37.2 0.5 8.5e-05 22.4 0.3 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKF95006.1 - 3.7e-09 37.1 0.2 1.7e-06 28.6 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKF95006.1 - 5.9e-09 35.4 0.0 0.029 14.6 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKF95006.1 - 7.4e-09 35.1 0.1 0.00034 20.2 0.1 3.8 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.28 KKF95006.1 - 3.5e-07 29.7 0.1 5.2e-05 22.9 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKF95006.1 - 2e-06 28.0 0.8 0.021 15.1 0.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKF95006.1 - 2.5e-06 27.5 0.1 0.001 19.3 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKF95006.1 - 3.2e-05 24.0 0.9 0.0002 21.5 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKF95006.1 - 4.9e-05 23.7 0.4 0.75 10.6 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKF95006.1 - 8.3e-05 22.3 1.1 0.7 10.1 0.1 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 KKF95006.1 - 0.00077 19.9 0.7 0.12 12.8 0.0 2.6 3 0 0 3 3 3 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KKF95006.1 - 0.025 14.8 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KKF95006.1 - 0.029 14.7 0.2 0.77 10.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_1N PF02870.15 KKF95006.1 - 0.052 14.3 0.0 9.3 7.1 0.0 2.5 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Wzy_C_2 PF11846.8 KKF95006.1 - 0.081 12.8 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal PPR_3 PF13812.6 KKF95006.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Methyltransf_25 PF13649.6 KKF95007.1 - 4.3e-14 53.0 0.0 7.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF95007.1 - 3.4e-13 50.2 0.0 1e-12 48.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF95007.1 - 7.1e-11 42.6 0.0 1.4e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF95007.1 - 1.2e-10 41.5 0.0 1.8e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF95007.1 - 2.2e-08 34.0 0.0 3.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKF95007.1 - 1.3e-06 27.9 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KKF95007.1 - 9.8e-05 23.3 0.0 0.00023 22.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KKF95007.1 - 0.00012 21.3 0.0 0.18 10.9 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 KKF95007.1 - 0.00024 21.0 0.2 0.0069 16.2 0.0 2.6 1 1 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 KKF95007.1 - 0.0035 16.9 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DUF3419 PF11899.8 KKF95007.1 - 0.018 14.2 0.0 0.087 12.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3419) Methyltransf_32 PF13679.6 KKF95007.1 - 0.031 14.3 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Y_phosphatase3 PF13350.6 KKF95008.1 - 1.5e-29 103.6 0.0 2.3e-25 90.0 0.0 2.0 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KKF95008.1 - 2.4e-06 27.2 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 KKF95008.1 - 2.3e-05 23.5 0.0 4.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KKF95008.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KKF95008.1 - 0.0075 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Eisosome1 PF12757.7 KKF95009.1 - 1.2e-25 90.1 12.6 1.2e-25 90.1 12.6 4.2 2 2 2 4 4 4 1 Eisosome protein 1 GOLD_2 PF13897.6 KKF95009.1 - 0.001 19.5 0.9 0.0063 17.0 0.9 2.4 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking Proteasome PF00227.26 KKF95010.1 - 4e-30 104.7 0.3 8.3e-30 103.7 0.3 1.5 1 1 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.27 KKF95011.1 - 8.8e-40 137.1 0.1 1.6e-37 129.7 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KKF95011.1 - 2.5e-24 85.7 0.1 5e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cation_efflux PF01545.21 KKF95012.1 - 6.6e-25 88.0 10.4 8.9e-25 87.6 10.4 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KKF95012.1 - 4.3e-06 26.8 0.0 8.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Het-C PF07217.11 KKF95013.1 - 2.8e-226 752.5 0.0 4e-226 751.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF2291 PF10054.9 KKF95013.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) HMG_box PF00505.19 KKF95014.1 - 6.2e-07 29.7 0.4 1.2e-06 28.8 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKF95014.1 - 0.00023 21.7 0.3 0.00062 20.3 0.1 1.8 2 0 0 2 2 2 1 HMG-box domain Amidohydro_1 PF01979.20 KKF95015.1 - 3.2e-75 253.6 0.4 5.6e-75 252.8 0.4 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KKF95015.1 - 1.6e-55 186.6 0.4 3.6e-55 185.5 0.4 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Ada3 PF10198.9 KKF95015.1 - 1.8e-52 177.0 0.0 1.8e-52 177.0 0.0 2.4 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Urease_beta PF00699.20 KKF95015.1 - 1.2e-40 137.5 0.1 2.2e-40 136.7 0.1 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KKF95015.1 - 1.3e-19 70.3 0.0 3.1e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KKF95015.1 - 5.9e-09 35.9 0.2 1.6e-05 24.6 0.0 2.3 1 1 0 2 2 2 2 Amidohydrolase family Raftlin PF15250.6 KKF95015.1 - 0.55 8.9 6.9 0.89 8.2 6.9 1.2 1 0 0 1 1 1 0 Raftlin LRIF1 PF15741.5 KKF95015.1 - 0.96 7.9 12.6 1.4 7.4 12.6 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 SWIRM-assoc_2 PF16496.5 KKF95015.1 - 2.9 6.7 17.8 4.8 5.9 17.8 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Sporozoite_P67 PF05642.11 KKF95016.1 - 0.11 10.6 4.9 0.11 10.6 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDP-OH_P_transf PF01066.21 KKF95017.1 - 2.6e-17 63.3 0.3 2.6e-17 63.3 0.3 3.0 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Glyco_hydro_47 PF01532.20 KKF95018.1 - 2.1e-155 518.1 0.0 2.4e-155 517.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Utp11 PF03998.13 KKF95019.1 - 2.9e-57 194.4 17.6 3.4e-57 194.2 17.6 1.0 1 0 0 1 1 1 1 Utp11 protein Nop53 PF07767.11 KKF95019.1 - 0.0055 16.2 10.6 0.0055 16.2 10.6 2.2 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) RIC3 PF15361.6 KKF95019.1 - 0.072 13.5 0.6 0.072 13.5 0.6 2.3 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Imm5 PF14423.6 KKF95019.1 - 0.14 12.4 4.3 0.5 10.6 1.2 2.3 2 0 0 2 2 2 0 Immunity protein Imm5 EMP24_GP25L PF01105.24 KKF95019.1 - 0.14 12.0 2.4 0.26 11.2 2.4 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD RRN3 PF05327.11 KKF95019.1 - 0.34 9.4 6.6 0.42 9.1 6.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SLATT_5 PF18160.1 KKF95019.1 - 0.39 10.0 3.3 0.12 11.7 0.4 1.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 CDC45 PF02724.14 KKF95019.1 - 0.55 8.5 8.3 0.87 7.8 8.3 1.4 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KKF95019.1 - 4.3 5.3 16.1 5.7 4.9 16.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi AlaDh_PNT_N PF05222.15 KKF95021.1 - 6.5e-27 94.5 0.0 1.4e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DAO PF01266.24 KKF95021.1 - 1.6e-11 44.4 2.5 1.5e-05 24.7 1.2 2.6 1 1 1 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKF95021.1 - 1.2e-07 31.2 1.0 0.00036 19.9 0.0 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KKF95021.1 - 0.00056 19.1 0.2 0.00095 18.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KKF95021.1 - 0.0052 17.2 0.0 0.0099 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KKF95021.1 - 0.0099 15.2 0.1 0.019 14.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKF95021.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKF95021.1 - 0.027 15.0 0.6 0.056 14.0 0.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKF95021.1 - 0.032 14.5 1.6 0.096 12.9 1.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KKF95021.1 - 0.034 13.8 0.2 0.17 11.5 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KKF95021.1 - 0.036 13.4 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KKF95021.1 - 0.075 12.3 0.5 0.19 10.9 0.5 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKF95021.1 - 0.084 12.1 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 KKF95021.1 - 0.11 12.0 0.2 0.25 10.9 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KKF95021.1 - 0.17 11.7 1.1 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KKF95021.1 - 0.27 10.3 0.1 0.4 9.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Cmc1 PF08583.10 KKF95022.1 - 0.0046 17.0 0.2 0.0046 17.0 0.2 2.0 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like eIF3_N PF09440.10 KKF95022.1 - 0.079 13.4 0.3 0.1 13.1 0.3 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain TetR_C_28 PF17937.1 KKF95022.1 - 0.11 13.0 3.7 0.3 11.6 3.7 1.7 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain V-ATPase_G_2 PF16999.5 KKF95022.1 - 1.5 9.3 12.2 3.3 8.2 12.2 1.6 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit fn3 PF00041.21 KKF95023.1 - 2.3e-08 34.3 0.0 7e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Golgin_A5 PF09787.9 KKF95023.1 - 0.11 12.0 35.8 0.23 10.9 20.7 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Minor_capsid_3 PF12691.7 KKF95023.1 - 0.2 12.0 2.0 0.25 11.7 0.1 2.1 2 0 0 2 2 2 0 Minor capsid protein from bacteriophage ADH_N PF08240.12 KKF95024.1 - 7.4e-32 109.5 0.3 7.4e-32 109.5 0.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKF95024.1 - 1.3e-22 80.2 0.3 2.4e-22 79.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKF95024.1 - 1.2e-05 26.4 0.0 1.8e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 KKF95024.1 - 0.26 11.5 1.3 0.71 10.1 0.3 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HMA PF00403.26 KKF95025.1 - 3.3e-15 56.3 0.4 4.3e-15 55.9 0.4 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Fungal_trans PF04082.18 KKF95026.1 - 3.4e-10 39.4 1.0 3.4e-10 39.4 1.0 2.8 2 2 1 3 3 3 1 Fungal specific transcription factor domain His_Me_b4a2 PF18275.1 KKF95026.1 - 0.18 11.9 2.3 0.43 10.7 2.3 1.6 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain PNISR PF15996.5 KKF95026.1 - 5.8 7.1 21.1 12 6.1 21.1 1.6 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Presenilin PF01080.17 KKF95026.1 - 8.4 5.0 23.9 14 4.3 23.9 1.3 1 0 0 1 1 1 0 Presenilin Tcf25 PF04910.14 KKF95027.1 - 8.2e-42 143.5 0.0 1.5e-41 142.6 0.0 1.5 2 0 0 2 2 2 1 Transcriptional repressor TCF25 YL1 PF05764.13 KKF95027.1 - 0.066 13.3 8.3 0.14 12.3 8.3 1.5 1 0 0 1 1 1 0 YL1 nuclear protein AIP3 PF03915.13 KKF95028.1 - 1.6e-150 501.8 3.6 2.2e-150 501.3 3.6 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 PKK PF12474.8 KKF95028.1 - 0.0072 16.5 2.4 0.0072 16.5 2.4 2.2 2 0 0 2 2 2 1 Polo kinase kinase Zw10 PF06248.13 KKF95028.1 - 0.15 10.6 0.9 0.32 9.5 0.5 1.8 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 DUF1664 PF07889.12 KKF95028.1 - 0.48 10.5 6.9 3.9 7.5 0.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KKF95028.1 - 1.2 9.7 5.8 3.7 8.1 0.2 4.4 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein T7SS_ESX_EspC PF10824.8 KKF95028.1 - 3 8.4 5.9 1.9 9.0 0.1 3.7 4 1 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm ATG16 PF08614.11 KKF95028.1 - 6.3 7.0 11.9 2.5 8.3 2.9 3.7 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Sugar_tr PF00083.24 KKF95029.1 - 2.8e-108 362.7 19.4 3.6e-108 362.3 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF95029.1 - 1.7e-27 96.3 23.0 1.7e-27 96.3 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKF95029.1 - 6.3e-06 24.9 5.3 6.3e-06 24.9 5.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KKF95029.1 - 0.00073 18.1 5.5 0.00073 18.1 5.5 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector LacY_symp PF01306.19 KKF95029.1 - 0.13 11.0 9.0 1.2 7.8 0.8 2.3 2 0 0 2 2 2 0 LacY proton/sugar symporter MFS_1 PF07690.16 KKF95030.1 - 3.6e-39 134.7 40.6 3.6e-39 134.7 40.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5577 PF17740.1 KKF95030.1 - 0.035 13.8 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5577) Ribosomal_L3 PF00297.22 KKF95031.1 - 5.2e-179 594.9 10.9 6e-179 594.8 10.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Big_3_3 PF13750.6 KKF95031.1 - 0.047 13.3 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) TPR_1 PF00515.28 KKF95033.1 - 1.3e-50 167.2 22.5 3.7e-08 32.9 0.1 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 KKF95033.1 - 2.7e-42 139.5 22.9 1.3e-05 24.9 0.0 10.0 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 KKF95033.1 - 2.7e-39 130.1 19.2 3.7e-07 29.8 0.0 9.9 9 1 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.6 KKF95033.1 - 9.6e-28 96.6 5.9 2.3e-06 28.1 0.4 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KKF95033.1 - 2e-27 93.5 7.4 0.00073 20.2 0.1 9.2 3 3 6 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.6 KKF95033.1 - 5.3e-26 89.1 14.5 0.00063 19.9 0.1 9.0 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KKF95033.1 - 5e-21 75.0 12.7 2.6e-05 24.6 0.1 6.5 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 KKF95033.1 - 7.3e-20 70.4 26.8 2.3e-06 27.2 0.2 8.7 4 3 4 8 8 8 5 TPR repeat TPR_12 PF13424.6 KKF95033.1 - 4.1e-19 68.7 20.8 2.7e-05 24.4 1.0 6.9 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 KKF95033.1 - 3.6e-18 64.9 14.5 0.0095 16.5 0.6 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKF95033.1 - 6.4e-18 63.4 16.4 0.0063 16.5 0.1 8.6 7 2 1 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF95033.1 - 2.6e-15 56.4 8.5 3.7e-09 36.7 1.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KKF95033.1 - 5.4e-14 52.1 9.0 0.0005 20.2 0.2 6.5 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_15 PF13429.6 KKF95033.1 - 7e-11 41.9 7.0 0.00077 18.7 0.2 4.8 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.9 KKF95033.1 - 1e-08 35.1 4.1 0.11 12.2 0.0 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 KKF95033.1 - 7e-06 26.3 1.9 0.037 14.3 0.0 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.17 KKF95033.1 - 0.00042 20.8 5.1 0.35 11.3 0.1 3.1 2 1 1 3 3 3 2 Bacterial transcriptional activator domain DUF2225 PF09986.9 KKF95033.1 - 0.002 17.9 1.1 0.6 9.8 0.0 3.2 1 1 2 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.10 KKF95033.1 - 0.013 14.6 0.8 0.18 10.7 0.1 2.4 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 KKF95033.1 - 0.053 13.4 20.8 5.6 7.0 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF2989 PF11207.8 KKF95033.1 - 0.15 11.8 2.1 5.3 6.7 0.1 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF2989) Cohesin_load PF10345.9 KKF95033.1 - 0.36 9.2 2.5 21 3.4 0.0 2.8 2 1 1 3 3 3 0 Cohesin loading factor DUF1751 PF08551.10 KKF95034.1 - 4.9e-26 91.2 4.5 1.1e-25 90.1 4.5 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) HupE_UreJ PF04955.12 KKF95034.1 - 0.013 15.0 2.6 0.22 11.0 0.5 2.7 2 1 0 2 2 2 0 HupE / UreJ protein NUDIX-like PF09296.11 KKF95034.1 - 0.13 13.0 0.8 0.24 12.1 0.8 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain Rhomboid PF01694.22 KKF95034.1 - 4.6 7.2 19.4 0.58 10.1 13.5 2.1 2 1 0 2 2 2 0 Rhomboid family WD40 PF00400.32 KKF95035.1 - 5.6e-08 33.3 0.0 0.017 16.0 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat LisH PF08513.11 KKF95035.1 - 1.9e-07 30.7 0.1 3.7e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 LisH NuiA PF07924.11 KKF95036.1 - 0.011 16.1 0.0 4.2 7.8 0.0 2.4 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein Chorismate_bind PF00425.18 KKF95037.1 - 1.4e-90 303.4 0.0 2.5e-90 302.6 0.0 1.4 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KKF95037.1 - 7.2e-29 100.8 0.0 1.5e-24 86.8 0.0 3.5 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region PCM1_C PF15717.5 KKF95038.1 - 0.031 13.0 18.7 0.041 12.6 18.7 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus GREB1 PF15782.5 KKF95038.1 - 0.26 8.4 24.6 0.32 8.1 24.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1387 PF07139.11 KKF95038.1 - 1.6 8.4 21.8 3.4 7.3 21.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Neur_chan_memb PF02932.16 KKF95038.1 - 3.3 7.7 19.3 0.37 10.8 15.2 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4775 PF16001.5 KKF95038.1 - 5.1 6.4 13.3 6.9 6.0 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) DUF4638 PF15472.6 KKF95038.1 - 5.3 6.7 17.8 8.9 6.0 17.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Membralin PF09746.9 KKF95038.1 - 5.9 5.8 16.3 8.4 5.3 16.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein AMP-binding PF00501.28 KKF95039.1 - 9.6e-90 301.2 0.1 1.3e-89 300.8 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKF95039.1 - 3.6e-27 95.1 2.3 1.8e-25 89.7 1.1 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KKF95039.1 - 4.3e-18 65.0 0.5 1.3e-17 63.5 0.5 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Ribosomal_L16 PF00252.18 KKF95040.1 - 4.4e-30 104.4 1.0 5.1e-29 100.9 0.4 2.3 2 0 0 2 2 2 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.6 KKF95040.1 - 1.6e-09 37.8 0.0 2.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KKF95040.1 - 3.9e-06 27.3 0.1 1e-05 26.0 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKF95040.1 - 0.00014 22.1 0.1 0.0029 17.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rep_fac_C PF08542.11 KKF95040.1 - 0.00026 21.3 0.0 0.00069 20.0 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_24 PF13479.6 KKF95040.1 - 0.00086 19.1 0.2 0.0023 17.7 0.2 1.7 1 1 0 1 1 1 1 AAA domain bMG6 PF17962.1 KKF95040.1 - 0.015 15.4 0.3 8.3 6.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 ABC_tran PF00005.27 KKF95040.1 - 0.02 15.4 0.0 0.044 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KKF95040.1 - 0.033 14.6 1.4 1.1 9.6 0.3 2.9 2 1 0 2 2 2 0 AAA ATPase domain RFC1 PF08519.12 KKF95041.1 - 4e-58 196.0 0.0 8.3e-58 195.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KKF95041.1 - 5.4e-16 58.7 0.0 1.3e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KKF95041.1 - 1.3e-07 32.1 0.0 3.3e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KKF95041.1 - 3.8e-05 23.7 0.0 7.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KKF95041.1 - 0.00031 21.0 0.0 0.0013 19.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKF95041.1 - 0.0023 17.7 0.0 0.0065 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKF95041.1 - 0.0056 17.1 1.8 0.0096 16.3 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_28 PF13521.6 KKF95041.1 - 0.0069 16.6 0.4 0.07 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 KKF95041.1 - 0.02 14.7 0.1 0.075 12.8 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_18 PF13238.6 KKF95041.1 - 0.032 14.8 0.0 0.096 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKF95041.1 - 0.036 14.1 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKF95041.1 - 0.043 14.0 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PTCB-BRCT PF12738.7 KKF95041.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain RuvB_N PF05496.12 KKF95041.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KKF95041.1 - 0.16 11.9 0.0 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain DUF3987 PF13148.6 KKF95041.1 - 2 7.3 8.5 6.3 5.7 8.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) GrpE PF01025.19 KKF95042.1 - 2.5e-45 154.1 2.4 4.2e-45 153.4 2.4 1.3 1 0 0 1 1 1 1 GrpE Het-C PF07217.11 KKF95043.1 - 7.3e-273 906.2 0.0 9.1e-273 905.9 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C ADH_zinc_N PF00107.26 KKF95044.1 - 2.9e-12 46.7 0.0 6.4e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKF95044.1 - 4.4e-06 26.5 0.1 1.3e-05 25.1 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KKF95044.1 - 0.0021 19.1 0.0 0.0045 18.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HTH_48 PF17906.1 KKF95045.1 - 0.087 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Exo_endo_phos PF03372.23 KKF95047.1 - 5.7e-17 62.0 0.0 9.6e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1275 PF06912.11 KKF95047.1 - 0.024 14.6 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) FA_desaturase PF00487.24 KKF95047.1 - 0.7 9.7 5.3 0.12 12.2 1.1 1.7 2 0 0 2 2 2 0 Fatty acid desaturase WD40 PF00400.32 KKF95048.1 - 9.1e-50 165.6 27.0 1.3e-09 38.5 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF95048.1 - 1.7e-19 69.9 0.0 0.00015 21.9 0.0 6.1 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKF95048.1 - 5.1e-07 28.7 1.6 1.2 7.7 0.1 4.8 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKF95048.1 - 5.3e-06 25.6 0.5 0.5 9.3 0.0 4.0 2 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KKF95048.1 - 5.4e-05 23.2 0.0 0.0013 18.7 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KKF95048.1 - 0.0002 20.2 2.3 0.75 8.5 0.0 3.6 3 1 1 4 4 4 2 Nup133 N terminal like VID27 PF08553.10 KKF95048.1 - 0.0054 15.8 0.1 1.1 8.2 0.0 3.8 3 2 2 5 5 5 1 VID27 C-terminal WD40-like domain WD40_like PF17005.5 KKF95048.1 - 0.012 15.0 0.0 4.1 6.6 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain Frtz PF11768.8 KKF95048.1 - 0.17 10.2 0.0 0.64 8.3 0.0 1.9 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz SOG2 PF10428.9 KKF95048.1 - 8.5 5.4 10.6 12 5.0 10.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein ClpS PF02617.17 KKF95049.1 - 3e-08 33.4 0.0 7.7e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UCR_UQCRX_QCR9 PF05365.12 KKF95050.1 - 5.7e-21 74.2 0.7 1.1e-20 73.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like FIVAR PF07554.13 KKF95051.1 - 0.19 12.5 0.4 0.38 11.6 0.4 1.4 1 0 0 1 1 1 0 FIVAR domain Sortilin-Vps10 PF15902.5 KKF95052.1 - 9e-258 855.3 16.4 3.4e-133 444.7 0.9 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KKF95052.1 - 7.4e-84 280.3 21.8 9.1e-46 156.3 6.8 2.9 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KKF95052.1 - 1e-11 43.0 41.7 1.1 9.5 2.1 11.7 10 0 0 10 10 10 7 BNR/Asp-box repeat BNR_2 PF13088.6 KKF95052.1 - 0.0003 20.2 10.1 0.49 9.6 0.0 6.2 4 3 0 5 5 5 3 BNR repeat-like domain PSII_BNR PF14870.6 KKF95052.1 - 0.00046 19.5 6.9 0.024 13.9 0.1 5.0 5 2 0 5 5 5 1 Photosynthesis system II assembly factor YCF48 CHB_HEX_C PF03174.13 KKF95052.1 - 0.038 14.0 3.3 18 5.4 0.0 5.6 6 0 0 6 6 6 0 Chitobiase/beta-hexosaminidase C-terminal domain Mo-co_dimer PF03404.16 KKF95052.1 - 0.058 13.4 1.3 44 4.1 0.1 4.8 5 0 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain preSET_CXC PF18264.1 KKF95052.1 - 3.9 8.0 10.6 6.6 7.3 0.8 2.7 2 0 0 2 2 2 0 CXC domain LAM_C PF12544.8 KKF95053.1 - 0.00025 21.2 0.0 0.00054 20.1 0.0 1.5 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 KKF95053.1 - 0.11 12.9 0.5 0.64 10.4 0.5 2.2 1 1 0 1 1 1 0 Radical SAM superfamily WLM PF08325.10 KKF95054.1 - 9.7e-30 104.1 0.0 1.5e-29 103.4 0.0 1.4 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 KKF95054.1 - 1.9e-06 28.1 3.5 3.8e-06 27.1 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Enolase_C PF00113.22 KKF95055.1 - 3.4e-151 502.5 0.1 4.5e-151 502.2 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KKF95055.1 - 6.7e-59 197.8 0.1 1.2e-58 197.0 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KKF95055.1 - 6.1e-06 26.0 0.0 9.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KKF95055.1 - 0.0036 16.5 0.4 0.74 8.9 0.1 3.0 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus Mad3_BUB1_I PF08311.12 KKF95056.1 - 4.8e-43 146.1 1.0 4.8e-43 146.1 1.0 2.4 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KKF95056.1 - 7.8e-10 38.8 0.0 6e-08 32.7 0.0 4.0 5 1 0 5 5 5 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KKF95056.1 - 3.8e-08 33.0 0.0 3.4e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95056.1 - 0.00029 20.2 0.0 0.0013 18.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KKF95056.1 - 0.049 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein zf-H2C2_2 PF13465.6 KKF95057.1 - 1.1e-07 31.9 3.3 1.1e-07 31.9 3.3 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KKF95057.1 - 5.5e-05 23.4 9.0 0.1 13.1 4.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKF95057.1 - 0.00045 20.8 7.6 0.62 11.1 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KKF95057.1 - 0.15 12.0 0.7 0.36 10.8 0.7 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KKF95057.1 - 0.8 9.8 7.1 0.33 11.0 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger ERCC3_RAD25_C PF16203.5 KKF95058.1 - 1.5e-115 384.6 0.2 3.8e-115 383.3 0.2 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KKF95058.1 - 2.2e-31 108.6 0.0 6e-31 107.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF95058.1 - 4.3e-16 59.4 0.0 9.1e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKF95058.1 - 1.3e-12 48.0 0.1 2e-11 44.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KKF95058.1 - 9.5e-07 27.8 0.0 1.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KKF95058.1 - 0.00013 21.8 0.0 0.00051 19.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AP_endonuc_2 PF01261.24 KKF95059.1 - 1.4e-28 99.8 0.0 2.1e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Haem_degrading PF03928.14 KKF95060.1 - 4e-31 107.5 0.0 5.7e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Haem-degrading SUN PF03856.13 KKF95061.1 - 6.9e-84 281.1 6.1 1e-83 280.6 6.1 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) CDC27 PF09507.10 KKF95061.1 - 1.9 7.8 4.7 2.6 7.3 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AICARFT_IMPCHas PF01808.18 KKF95062.1 - 3.2e-89 299.3 0.0 5.1e-89 298.6 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KKF95062.1 - 1e-24 86.5 0.0 1.9e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Lactamase_B_2 PF12706.7 KKF95062.1 - 0.14 11.7 0.1 10 5.6 0.0 2.7 3 0 0 3 3 3 0 Beta-lactamase superfamily domain MFS_1 PF07690.16 KKF95063.1 - 1.2e-13 50.8 16.4 1.2e-13 50.8 16.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3165 PF11364.8 KKF95063.1 - 0.13 12.6 9.3 1.5 9.2 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3165) Hist_deacetyl PF00850.19 KKF95064.1 - 6.7e-82 275.4 0.0 9.2e-82 275.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.7 KKF95065.1 - 7.9e-20 71.3 2.2 1.2e-19 70.7 2.2 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KKF95065.1 - 5.7e-05 22.9 8.9 5.7e-05 22.9 8.9 1.7 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 KKF95065.1 - 0.15 12.3 1.1 0.33 11.2 1.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 KKF95065.1 - 0.44 10.9 6.2 0.79 10.1 6.2 1.4 1 0 0 1 1 1 0 Ring finger domain UDPGP PF01704.18 KKF95066.1 - 1.2e-191 636.9 0.1 1.4e-191 636.6 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF3605 PF12239.8 KKF95067.1 - 8.8e-51 172.2 0.0 1.1e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.18 KKF95068.1 - 4.3e-22 78.8 0.0 3.4e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase SPX PF03105.19 KKF95069.1 - 6.9e-09 36.1 0.1 4.9e-06 26.7 0.0 2.0 1 1 1 2 2 2 2 SPX domain DPCD PF14913.6 KKF95069.1 - 0.051 12.9 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 DPCD protein family DUF2661 PF10860.8 KKF95069.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) Endosulfine PF04667.17 KKF95070.1 - 1.8e-27 95.3 0.2 1.8e-27 95.3 0.2 1.8 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region BESS PF02944.20 KKF95070.1 - 0.21 11.4 0.7 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 BESS motif UPF0160 PF03690.13 KKF95071.1 - 1.3e-127 425.8 0.0 1.5e-127 425.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ino80_Iec3 PF14612.6 KKF95072.1 - 3.4e-45 155.6 2.4 5.6e-25 89.4 1.9 2.3 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling KinB_sensor PF16767.5 KKF95072.1 - 0.2 12.1 0.9 0.4 11.1 0.9 1.4 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Iso_dh PF00180.20 KKF95073.1 - 1.2e-72 245.0 0.0 1.4e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-C2H2 PF00096.26 KKF95074.1 - 0.0042 17.5 4.6 0.0042 17.5 4.6 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type FAA_hydrolase PF01557.18 KKF95075.1 - 1.8e-50 171.6 0.0 2.2e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.12 KKF95076.1 - 6e-62 207.8 0.0 6.9e-62 207.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KKF95076.1 - 8e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KKF95076.1 - 0.00037 20.1 0.1 0.00052 19.6 0.1 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 KKF95076.1 - 0.0063 16.7 0.1 0.01 16.0 0.1 1.3 1 0 0 1 1 1 1 ARD/ARD' family DZR PF12773.7 KKF95076.1 - 0.0096 15.9 2.1 0.019 14.9 2.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon AraC_binding PF02311.19 KKF95076.1 - 0.02 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_4 PF08007.12 KKF95076.1 - 0.061 12.8 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein IBR PF01485.21 KKF95076.1 - 0.072 13.3 1.2 0.13 12.5 1.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PknG_rubred PF16919.5 KKF95076.1 - 0.074 13.2 0.3 0.12 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain Ctr PF04145.15 KKF95077.1 - 2.9e-27 96.1 14.2 1.6e-25 90.4 14.2 2.0 1 1 0 1 1 1 1 Ctr copper transporter family HemY_N PF07219.13 KKF95077.1 - 9.9 6.4 8.3 0.64 10.2 2.2 2.0 1 1 1 2 2 2 0 HemY protein N-terminus NUDIX PF00293.28 KKF95078.1 - 3e-08 33.8 0.0 5.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Pex2_Pex12 PF04757.14 KKF95079.1 - 1.7e-39 135.7 2.1 2.3e-39 135.3 2.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KKF95079.1 - 6.1e-11 42.0 9.2 1e-10 41.2 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKF95079.1 - 6.4e-11 42.4 9.2 1e-10 41.7 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KKF95079.1 - 3.1e-10 39.7 6.5 4.7e-10 39.2 6.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKF95079.1 - 1.1e-09 38.0 7.4 1.7e-09 37.4 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KKF95079.1 - 7e-08 32.5 7.9 1.2e-07 31.8 7.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KKF95079.1 - 1.5e-07 31.4 4.8 2.7e-07 30.5 4.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KKF95079.1 - 2.2e-07 31.1 6.6 4.2e-07 30.1 6.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KKF95079.1 - 3.4e-07 30.1 6.0 5.4e-07 29.5 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KKF95079.1 - 2.2e-06 27.4 7.2 3.6e-06 26.7 7.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KKF95079.1 - 4.3e-06 26.5 2.1 8.7e-06 25.5 2.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KKF95079.1 - 0.0021 18.2 6.0 0.0035 17.5 6.0 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 KKF95079.1 - 0.013 15.3 2.2 0.027 14.3 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KKF95079.1 - 0.072 13.1 2.7 0.14 12.2 2.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KKF95079.1 - 0.21 11.4 7.8 0.4 10.5 7.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KKF95079.1 - 1.1 8.9 6.3 1.9 8.1 6.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Apt1 PF10351.9 KKF95080.1 - 0.35 9.7 11.0 0.44 9.3 11.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KKF95080.1 - 0.73 8.3 12.1 0.86 8.1 12.1 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 KKF95080.1 - 2.2 7.4 14.4 2.7 7.1 14.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 KKF95080.1 - 5.1 5.8 7.3 6.8 5.3 7.3 1.2 1 0 0 1 1 1 0 Presenilin DUF2347 PF09804.9 KKF95080.1 - 6.5 6.2 7.7 2.8 7.5 5.5 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Hydrolase_4 PF12146.8 KKF95081.1 - 2.8e-19 69.3 0.0 9.6e-13 48.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKF95081.1 - 1.7e-12 47.6 0.2 5.7e-07 29.4 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKF95081.1 - 2.8e-07 31.4 0.1 6.8e-05 23.6 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KKF95081.1 - 1.5e-06 27.9 0.0 2.9e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 KKF95081.1 - 3e-05 22.8 0.0 0.031 13.0 0.0 2.7 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KKF95081.1 - 8.8e-05 22.1 0.0 0.0018 17.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 KKF95081.1 - 0.00013 21.7 0.0 0.0003 20.5 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.12 KKF95081.1 - 0.00028 20.0 0.0 0.00039 19.5 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 KKF95081.1 - 0.00043 20.2 0.1 0.37 10.6 0.0 2.8 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 KKF95081.1 - 0.0011 18.8 0.0 0.06 13.1 0.1 2.2 1 1 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KKF95081.1 - 0.005 16.8 0.0 0.9 9.4 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1057 PF06342.12 KKF95081.1 - 0.0085 15.2 0.1 0.018 14.1 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 KKF95081.1 - 0.048 13.5 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KKF95081.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 KKF95081.1 - 0.2 11.3 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Dopey_N PF04118.14 KKF95083.1 - 1.5e-45 155.6 0.1 8.3e-45 153.2 0.0 2.2 3 0 0 3 3 3 1 Dopey, N-terminal Methyltransf_15 PF09445.10 KKF95085.1 - 4.3e-34 117.5 0.0 5.5e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KKF95085.1 - 0.00037 20.2 0.0 0.0007 19.3 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KKF95085.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.14 KKF95085.1 - 0.2 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain GRASP55_65 PF04495.14 KKF95086.1 - 7.3e-44 149.4 0.0 6.6e-43 146.3 0.0 2.0 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KKF95086.1 - 0.00014 21.6 0.0 0.35 10.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KKF95086.1 - 0.059 13.7 0.0 9.9 6.6 0.0 2.5 2 0 0 2 2 2 0 PDZ domain DAD PF02109.16 KKF95087.1 - 1.7e-49 166.6 1.4 2.1e-49 166.4 1.4 1.1 1 0 0 1 1 1 1 DAD family MCD PF05292.11 KKF95087.1 - 0.19 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain Tmemb_14 PF03647.13 KKF95088.1 - 1.1e-22 80.5 7.2 1.3e-22 80.3 7.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 KKF95088.1 - 0.035 14.4 0.8 0.075 13.3 0.8 1.8 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 PHO4 PF01384.20 KKF95088.1 - 0.063 12.3 2.5 0.064 12.3 1.2 1.4 1 1 0 1 1 1 0 Phosphate transporter family Prefoldin_2 PF01920.20 KKF95089.1 - 3.1e-26 91.4 4.6 3.6e-26 91.2 4.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Taxilin PF09728.9 KKF95089.1 - 0.0012 18.1 2.6 0.052 12.7 0.5 2.0 2 0 0 2 2 2 2 Myosin-like coiled-coil protein Prefoldin PF02996.17 KKF95089.1 - 0.002 18.0 3.7 0.076 12.9 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit UvrD_C PF13361.6 KKF95089.1 - 0.013 14.8 0.9 0.015 14.7 0.9 1.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PriC PF07445.12 KKF95089.1 - 0.15 12.0 3.8 0.51 10.2 0.7 2.0 2 0 0 2 2 2 0 Primosomal replication protein priC GreA_GreB_N PF03449.15 KKF95089.1 - 0.39 10.9 4.4 0.35 11.0 0.6 2.2 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal RF-1 PF00472.20 KKF95089.1 - 0.44 10.5 4.5 0.79 9.7 0.5 2.1 2 0 0 2 2 2 0 RF-1 domain DUF2205 PF10224.9 KKF95089.1 - 0.63 10.1 5.8 1.3 9.0 0.5 2.1 2 0 0 2 2 2 0 Short coiled-coil protein Rho_Binding PF08912.11 KKF95089.1 - 2.4 9.0 10.6 1.4 9.7 2.3 2.2 2 0 0 2 2 2 0 Rho Binding CBFD_NFYB_HMF PF00808.23 KKF95090.1 - 1.4e-25 89.4 1.9 2.7e-25 88.4 1.9 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKF95090.1 - 2.1e-09 37.8 1.7 4.4e-09 36.8 1.7 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KKF95090.1 - 0.0019 18.2 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.16 KKF95090.1 - 0.002 18.1 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KKF95090.1 - 0.018 15.2 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold RRN3 PF05327.11 KKF95091.1 - 3.3e-153 511.2 0.0 3.3e-153 511.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 CSTF_C PF14304.6 KKF95092.1 - 0.9 9.2 4.2 2.2 7.9 0.1 2.7 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal PI-PLC-X PF00388.19 KKF95093.1 - 4.9e-12 45.6 0.0 9.7e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF1102 PF06510.11 KKF95093.1 - 0.092 12.9 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) bZIP_1 PF00170.21 KKF95094.1 - 0.019 15.1 2.7 0.042 13.9 2.7 1.6 1 0 0 1 1 1 0 bZIP transcription factor AAA_13 PF13166.6 KKF95094.1 - 0.021 13.5 0.6 0.034 12.8 0.6 1.2 1 0 0 1 1 1 0 AAA domain XkdW PF09636.10 KKF95094.1 - 0.052 13.6 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 XkdW protein DUF4962 PF16332.5 KKF95094.1 - 0.056 11.9 0.1 0.056 11.9 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4962) DUF2981 PF11200.8 KKF95094.1 - 0.17 11.6 3.5 1.9 8.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) DASH_Dam1 PF08653.10 KKF95094.1 - 0.24 11.2 1.1 0.48 10.3 1.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 Kelch_4 PF13418.6 KKF95095.1 - 1.6e-26 92.0 14.4 1.1e-07 31.7 0.0 7.0 7 1 0 7 7 7 5 Galactose oxidase, central domain DUF4110 PF13422.6 KKF95095.1 - 3.5e-26 91.1 0.1 3.5e-26 91.1 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 KKF95095.1 - 1.6e-22 79.2 13.8 7.9e-07 29.2 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KKF95095.1 - 3.1e-17 62.1 3.1 3.1e-06 27.1 0.1 6.1 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 KKF95095.1 - 6.9e-17 60.7 4.1 0.00022 21.1 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 KKF95095.1 - 2.7e-14 52.9 1.6 0.00069 19.8 0.2 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KKF95095.1 - 2.7e-11 42.9 1.2 0.011 15.3 0.0 4.9 4 1 0 4 4 4 3 Kelch motif Thioredoxin PF00085.20 KKF95096.1 - 6.1e-61 202.8 1.1 2.5e-29 101.3 0.1 4.0 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KKF95096.1 - 4.2e-44 150.7 2.1 5.7e-35 120.9 0.6 4.1 2 2 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KKF95096.1 - 2.3e-08 34.2 0.2 0.065 13.6 0.0 4.5 3 2 1 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.17 KKF95096.1 - 1.1e-07 31.3 1.3 2e-07 30.4 1.3 1.5 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_7 PF13899.6 KKF95096.1 - 8.1e-07 29.1 0.0 0.0037 17.4 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 KKF95096.1 - 1.2e-06 28.1 0.8 0.0091 15.4 0.0 2.9 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KKF95096.1 - 2.4e-06 27.4 0.6 0.1 12.6 0.1 2.9 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_2 PF13098.6 KKF95096.1 - 1.5e-05 25.4 1.6 0.17 12.4 0.1 3.5 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.10 KKF95096.1 - 2.6e-05 24.0 0.5 0.016 15.0 0.0 3.0 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.6 KKF95096.1 - 0.04 14.1 10.2 1.5 8.9 0.9 4.4 3 2 0 3 3 3 0 Thioredoxin Usp PF00582.26 KKF95096.1 - 1.1 9.7 4.2 1.5 9.3 0.1 2.5 2 0 0 2 2 2 0 Universal stress protein family TraF PF13728.6 KKF95096.1 - 2.9 7.6 5.2 3.1 7.6 0.0 3.1 3 0 0 3 3 2 0 F plasmid transfer operon protein CDK2AP PF09806.9 KKF95097.1 - 0.25 11.4 4.2 0.65 10.0 4.2 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DLIC PF05783.11 KKF95097.1 - 1.9 7.2 3.4 2.8 6.7 3.4 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) IBN_N PF03810.19 KKF95099.1 - 3.5e-15 55.7 0.1 2.5e-13 49.7 0.0 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 KKF95099.1 - 2.4e-09 36.5 0.0 7.7e-09 34.8 0.0 1.8 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 KKF95099.1 - 5e-07 29.9 4.4 3.5e-06 27.1 0.1 4.1 5 0 0 5 5 5 1 Exportin 1-like protein HEAT_2 PF13646.6 KKF95099.1 - 0.003 17.9 0.3 0.44 11.0 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 KKF95099.1 - 0.18 12.2 0.3 1.6 9.2 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat zf-RING_10 PF16685.5 KKF95099.1 - 0.19 11.9 0.3 0.51 10.5 0.3 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 MOR2-PAG1_C PF14225.6 KKF95099.1 - 0.49 10.2 3.1 1.1 9.0 0.1 3.1 4 0 0 4 4 4 0 Cell morphogenesis C-terminal Cnd1 PF12717.7 KKF95099.1 - 0.53 10.3 6.4 0.28 11.2 0.2 3.2 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 FliT PF05400.13 KKF95099.1 - 0.9 10.4 5.4 22 6.0 0.2 3.2 3 0 0 3 3 3 0 Flagellar protein FliT SR-25 PF10500.9 KKF95101.1 - 0.057 13.0 12.5 0.071 12.7 12.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NPR3 PF03666.13 KKF95101.1 - 0.062 12.1 3.3 0.072 11.9 3.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PNK3P PF08645.11 KKF95102.1 - 7.1e-53 178.6 0.0 1.3e-52 177.7 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Med18 PF09637.10 KKF95102.1 - 8.4e-17 61.8 0.0 1.3e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Med18 protein AAA_33 PF13671.6 KKF95102.1 - 1.8e-09 37.9 0.0 5.5e-08 33.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain Mito_carr PF00153.27 KKF95103.1 - 1.7e-36 124.0 0.7 1.5e-25 89.0 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein EF-hand_1 PF00036.32 KKF95103.1 - 2.3e-21 73.7 1.6 1.7e-07 30.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KKF95103.1 - 5.2e-19 66.5 5.1 6.1e-05 22.6 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KKF95103.1 - 1.3e-18 67.2 2.5 7.6e-09 35.9 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KKF95103.1 - 2.7e-17 61.4 5.2 3.6e-07 29.4 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KKF95103.1 - 1.9e-10 40.4 0.9 0.0016 18.2 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KKF95103.1 - 7.5e-08 32.7 0.4 0.014 15.7 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KKF95103.1 - 0.00033 20.6 3.0 0.27 11.2 0.3 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KKF95103.1 - 0.018 14.9 0.5 0.41 10.5 0.1 2.6 2 0 0 2 2 2 0 EF hand Glyco_transf_10 PF00852.19 KKF95103.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term Dockerin_1 PF00404.18 KKF95103.1 - 0.14 12.3 0.4 16 5.8 0.0 2.8 3 0 0 3 3 3 0 Dockerin type I domain Cyclin_N PF00134.23 KKF95104.1 - 2e-10 40.5 2.8 2.5e-10 40.2 1.6 1.9 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KKF95104.1 - 0.051 14.0 1.7 0.16 12.4 0.2 2.5 2 0 0 2 2 2 0 Cyclin C-terminal domain TFIIB PF00382.19 KKF95104.1 - 0.072 13.1 0.3 0.072 13.1 0.3 1.7 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Abhydrolase_6 PF12697.7 KKF95105.1 - 1e-13 52.4 3.8 1e-13 52.4 3.8 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKF95105.1 - 6.4e-13 48.9 0.1 1.7e-11 44.3 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKF95105.1 - 1.2e-11 44.4 0.0 3.6e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KKF95105.1 - 0.003 17.7 0.1 0.028 14.5 0.1 2.2 2 0 0 2 2 2 1 Thioesterase domain Esterase PF00756.20 KKF95105.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase SNARE PF05739.19 KKF95106.1 - 6.3e-06 26.1 1.1 1.5e-05 24.9 1.1 1.6 1 0 0 1 1 1 1 SNARE domain DUF3763 PF12592.8 KKF95106.1 - 0.1 12.7 0.2 0.99 9.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) SlyX PF04102.12 KKF95106.1 - 0.11 13.2 4.1 56 4.5 0.0 4.1 2 2 2 4 4 4 0 SlyX Vps39_1 PF10366.9 KKF95107.1 - 1.1e-33 115.7 0.0 3e-32 111.1 0.0 3.1 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 ANAPC3 PF12895.7 KKF95107.1 - 0.021 15.0 2.0 2.8 8.2 0.1 3.8 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KKF95107.1 - 0.039 13.8 7.4 2.5 8.0 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKF95107.1 - 0.074 13.4 6.9 10 6.5 0.4 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 KKF95107.1 - 0.091 12.6 1.7 0.47 10.3 0.3 2.7 3 1 0 3 3 3 0 Region in Clathrin and VPS TPR_16 PF13432.6 KKF95107.1 - 0.092 13.4 0.1 0.092 13.4 0.1 3.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKF95107.1 - 0.13 12.8 6.0 0.8 10.3 0.2 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKF95107.1 - 0.28 11.4 8.3 3.6 7.9 0.2 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKF95107.1 - 1.7 9.7 4.3 93 4.3 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat HbrB PF08539.11 KKF95108.1 - 2e-47 161.3 0.0 3.3e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 HbrB-like Defensin_propep PF00879.18 KKF95109.1 - 0.026 14.8 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 Defensin propeptide Sugar_tr PF00083.24 KKF95111.1 - 8.2e-87 291.9 22.2 9.7e-87 291.7 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF95111.1 - 1.6e-13 50.3 26.6 6.3e-13 48.4 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKF95111.1 - 0.31 9.9 17.4 0.011 14.7 4.7 2.4 2 1 0 2 2 2 0 MFS_1 like family CbtA PF09490.10 KKF95111.1 - 0.73 9.5 5.2 1.6 8.5 5.2 1.5 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Rxt3 PF08642.10 KKF95113.1 - 9.8e-44 149.2 0.0 1.4e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KKF95113.1 - 3.6e-08 33.4 0.0 3e-05 24.0 0.0 2.4 1 1 1 2 2 2 2 LCCL domain DUF1674 PF07896.12 KKF95114.1 - 5.1e-16 58.9 0.8 1.3e-15 57.6 0.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) TraG-D_C PF12696.7 KKF95114.1 - 0.097 12.7 0.8 0.14 12.2 0.8 1.1 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG BDHCT_assoc PF16204.5 KKF95114.1 - 0.2 11.3 4.0 0.25 11.0 4.0 1.1 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein SR-25 PF10500.9 KKF95114.1 - 2.8 7.5 10.7 3.4 7.2 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lyase_1 PF00206.20 KKF95115.1 - 1e-88 297.7 0.0 1.5e-88 297.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KKF95115.1 - 5.9e-23 81.4 0.1 1.4e-22 80.3 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Glycos_transf_1 PF00534.20 KKF95116.1 - 2.6e-20 72.6 0.0 6.1e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKF95116.1 - 2e-14 54.2 0.0 3.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KKF95116.1 - 0.00034 20.9 0.0 0.00076 19.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sod_Fe_C PF02777.18 KKF95117.1 - 3.5e-39 133.1 0.1 5.6e-39 132.4 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KKF95117.1 - 1.4e-30 105.6 1.9 2.4e-30 104.8 1.9 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sld5 PF05916.11 KKF95118.1 - 3.6e-09 37.1 0.0 4.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein TauD PF02668.16 KKF95119.1 - 1.6e-46 159.3 0.1 1.9e-46 159.0 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4645 PF15488.6 KKF95120.1 - 0.98 8.8 12.0 1.6 8.1 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) SMI1_KNR4 PF09346.10 KKF95121.1 - 4.2e-27 95.1 0.0 8.7e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) GATase_5 PF13507.6 KKF95122.1 - 4.4e-91 304.6 0.0 6.6e-91 304.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KKF95122.1 - 3.3e-35 121.5 0.1 2.6e-24 86.1 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KKF95122.1 - 1e-23 83.5 0.0 2.3e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KKF95122.1 - 3.3e-22 78.8 0.1 6.9e-22 77.7 0.1 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain PQ-loop PF04193.14 KKF95123.1 - 8.3e-18 63.9 7.0 7.3e-12 44.9 0.1 2.8 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KKF95123.1 - 0.0077 17.1 1.1 0.012 16.5 1.1 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor RAI1 PF08652.11 KKF95124.1 - 9.1e-27 93.1 0.0 1.9e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Pkinase PF00069.25 KKF95125.1 - 6.7e-63 212.5 0.0 7.7e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95125.1 - 1.3e-44 152.4 0.0 1.6e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF95125.1 - 1.9e-07 30.7 0.0 7e-06 25.6 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KKF95125.1 - 6.7e-07 28.4 0.0 1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KKF95125.1 - 0.079 12.6 0.0 4 7.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KKF95125.1 - 0.12 11.3 0.0 4.1 6.2 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 KKF95125.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKF95125.1 - 0.24 11.3 0.0 1.7 8.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Transglut_core PF01841.19 KKF95126.1 - 3.1e-08 34.1 0.0 8.1e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF3123 PF11321.8 KKF95126.1 - 5 7.8 9.3 8.3 7.1 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) FSA_C PF10479.9 KKF95126.1 - 9.5 4.2 10.1 16 3.5 10.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Glyco_hydro_16 PF00722.21 KKF95127.1 - 2.6e-07 30.3 0.2 4.2e-07 29.6 0.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Pribosyltran_N PF13793.6 KKF95128.1 - 8.6e-42 141.7 0.6 4e-41 139.6 0.1 2.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KKF95128.1 - 1.6e-39 135.9 3.3 1.4e-34 119.7 0.5 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KKF95128.1 - 3.4e-16 59.2 1.0 7.2e-16 58.1 1.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKF95128.1 - 0.00047 19.6 0.4 0.001 18.5 0.3 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase DPBB_1 PF03330.18 KKF95128.1 - 0.032 14.5 0.0 3.4 8.0 0.0 2.6 2 1 0 2 2 2 0 Lytic transglycolase DUF2235 PF09994.9 KKF95129.1 - 3.9e-85 285.7 0.0 6.2e-85 285.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) HLH PF00010.26 KKF95130.1 - 2e-12 46.8 0.2 5.3e-12 45.5 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cep57_CLD_2 PF14197.6 KKF95130.1 - 0.056 13.5 7.7 0.07 13.2 3.1 2.6 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 GIT1_C PF12205.8 KKF95130.1 - 0.11 12.6 4.3 0.16 12.1 2.4 2.1 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Terminase_3C PF17288.2 KKF95130.1 - 0.13 12.7 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Terminase RNAseH like domain Cnn_1N PF07989.11 KKF95130.1 - 0.22 11.7 3.7 0.13 12.4 0.9 2.1 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF3450 PF11932.8 KKF95130.1 - 7.3 5.8 11.1 0.24 10.7 3.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) PRKG1_interact PF15898.5 KKF95130.1 - 9 7.3 9.9 26 5.8 0.2 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain CLTH PF10607.9 KKF95131.1 - 4.8e-32 110.9 0.0 9.7e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KKF95131.1 - 5.6e-06 26.1 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 LisH DUF3450 PF11932.8 KKF95131.1 - 0.038 13.3 0.7 0.064 12.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) U-box PF04564.15 KKF95131.1 - 0.048 13.9 0.1 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 U-box domain LRR_RI_capping PF18779.1 KKF95131.1 - 0.17 11.6 2.4 0.47 10.1 2.4 1.7 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat RHH_5 PF07878.11 KKF95131.1 - 0.17 11.8 0.3 0.56 10.1 0.3 1.9 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 CAF1 PF04857.20 KKF95132.1 - 2.1e-16 60.0 0.0 1.8e-10 40.5 0.1 3.2 2 1 1 3 3 2 2 CAF1 family ribonuclease Presenilin PF01080.17 KKF95132.1 - 0.005 15.7 24.2 0.0069 15.2 24.2 1.1 1 0 0 1 1 1 1 Presenilin Zip PF02535.22 KKF95132.1 - 0.012 14.9 10.1 0.018 14.3 10.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RFX_DNA_binding PF02257.15 KKF95132.1 - 0.014 16.0 0.1 0.065 13.9 0.2 2.1 2 0 0 2 2 1 0 RFX DNA-binding domain SPX PF03105.19 KKF95132.1 - 0.081 12.8 15.7 0.023 14.6 13.2 1.4 2 0 0 2 2 2 0 SPX domain PAT1 PF09770.9 KKF95132.1 - 0.18 10.0 43.7 0.25 9.6 43.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mem_trans PF03547.18 KKF95132.1 - 0.19 10.1 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 Membrane transport protein ABC2_membrane_2 PF12679.7 KKF95132.1 - 0.33 10.2 0.7 0.43 9.8 0.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Endostatin PF06482.11 KKF95132.1 - 0.39 10.1 23.0 0.7 9.3 23.0 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Exonuc_VII_L PF02601.15 KKF95132.1 - 0.5 9.9 19.5 0.73 9.3 19.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Membralin PF09746.9 KKF95132.1 - 0.93 8.5 13.2 1.3 8.0 13.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein Peptidase_S15 PF02129.18 KKF95132.1 - 1.1 8.8 19.9 1.8 8.1 19.9 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) eIF-3_zeta PF05091.12 KKF95132.1 - 1.3 7.9 31.9 2.6 6.9 31.9 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Gti1_Pac2 PF09729.9 KKF95132.1 - 1.6 8.8 19.0 4.3 7.4 19.0 1.7 1 0 0 1 1 1 0 Gti1/Pac2 family Ndc1_Nup PF09531.10 KKF95132.1 - 2.8 6.5 20.8 7.6 5.1 20.5 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup PA26 PF04636.13 KKF95132.1 - 3.9 6.3 22.4 2.2 7.1 20.4 1.4 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) CAC1F_C PF16885.5 KKF95132.1 - 6.1 6.4 20.4 9.6 5.7 20.4 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Dapper PF15268.6 KKF95132.1 - 6.6 5.5 29.2 9 5.0 29.2 1.1 1 0 0 1 1 1 0 Dapper FAM76 PF16046.5 KKF95132.1 - 7.1 5.9 26.0 13 5.0 26.0 1.4 1 0 0 1 1 1 0 FAM76 protein SLC12 PF03522.15 KKF95132.1 - 8.3 5.3 29.4 12 4.8 29.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4045 PF13254.6 KKF95132.1 - 8.3 5.9 23.5 14 5.2 23.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GREB1 PF15782.5 KKF95132.1 - 8.4 3.4 26.0 11 3.0 26.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AUX_IAA PF02309.16 KKF95132.1 - 9.5 6.0 17.3 16 5.2 17.3 1.3 1 0 0 1 1 1 0 AUX/IAA family NDUF_B12 PF08122.12 KKF95133.1 - 1e-23 83.1 0.8 1.5e-23 82.6 0.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family eIF-6 PF01912.18 KKF95134.1 - 6e-80 267.3 0.7 8.5e-80 266.8 0.7 1.2 1 0 0 1 1 1 1 eIF-6 family ThiF PF00899.21 KKF95135.1 - 4.7e-26 91.6 0.0 7.8e-26 90.9 0.0 1.3 1 1 0 1 1 1 1 ThiF family DUF2130 PF09903.9 KKF95136.1 - 0.11 11.8 0.2 0.2 10.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF2431 PF10354.9 KKF95137.1 - 2.8e-62 209.9 0.0 3.5e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) SET PF00856.28 KKF95138.1 - 2.4e-18 67.1 2.3 1.2e-17 64.8 0.3 3.2 2 1 0 2 2 2 1 SET domain SRI PF08236.11 KKF95138.1 - 1.8e-17 63.3 3.3 5.6e-17 61.7 3.3 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 KKF95138.1 - 5.6e-11 42.3 10.1 5.6e-11 42.3 10.1 1.9 2 0 0 2 2 2 1 AWS domain WW PF00397.26 KKF95138.1 - 2.5e-06 27.4 2.0 6.2e-06 26.2 2.0 1.8 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 KKF95138.1 - 1.6e-05 24.8 0.2 9.2e-05 22.4 0.1 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain NDUFA12 PF05071.16 KKF95138.1 - 0.075 13.9 4.8 0.11 13.4 1.9 2.9 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 PQ-loop PF04193.14 KKF95139.1 - 7.8e-20 70.4 12.5 4.5e-12 45.6 0.7 2.9 3 0 0 3 3 3 2 PQ loop repeat zf-C2H2_4 PF13894.6 KKF95139.1 - 5.2e-06 26.8 1.8 0.15 13.0 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KKF95139.1 - 2.5e-05 24.5 2.0 0.096 13.2 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ribosomal_60s PF00428.19 KKF95139.1 - 2.3 8.9 11.3 0.1 13.2 2.6 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Rif1_N PF12231.8 KKF95140.1 - 5.8e-74 249.3 0.1 1.2e-73 248.2 0.1 1.5 1 1 0 1 1 1 1 Rap1-interacting factor 1 N terminal Mei4 PF13971.6 KKF95140.1 - 0.17 11.4 0.1 0.3 10.5 0.1 1.3 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Aldose_epim PF01263.20 KKF95141.1 - 5.5e-37 127.7 0.0 7.2e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.16 KKF95142.1 - 1e-200 666.9 0.0 1.1e-200 666.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family PTCB-BRCT PF12738.7 KKF95144.1 - 0.0061 16.5 0.1 0.086 12.8 0.1 2.3 1 1 0 1 1 1 1 twin BRCT domain zf-C4H2 PF10146.9 KKF95144.1 - 0.88 9.8 9.3 2.8 8.2 2.0 2.6 2 0 0 2 2 2 0 Zinc finger-containing protein PLA2_B PF01735.18 KKF95145.1 - 7e-177 588.7 3.9 8.2e-177 588.5 3.9 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF4377 PF14302.6 KKF95146.1 - 0.082 13.0 0.3 0.31 11.1 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4377) DHHC PF01529.20 KKF95147.1 - 0.00032 20.8 0.1 0.00053 20.1 0.1 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Myosin_head PF00063.21 KKF95148.1 - 6.9e-238 791.3 3.1 8.3e-238 791.0 3.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KKF95148.1 - 1.2e-49 168.5 0.0 2.6e-49 167.5 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KKF95148.1 - 8e-13 47.8 0.1 1.7e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKF95148.1 - 1e-08 34.9 0.0 2.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKF95148.1 - 1.8e-06 27.5 0.0 4.9e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 KKF95148.1 - 0.00049 19.6 9.7 0.017 14.8 1.6 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif SepF PF04472.12 KKF95148.1 - 0.0058 16.9 0.1 0.026 14.8 0.0 2.1 2 0 0 2 2 2 1 Cell division protein SepF Hpr_kinase_C PF07475.12 KKF95148.1 - 0.03 13.8 0.2 8.3 5.9 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 KKF95148.1 - 0.045 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKF95148.1 - 0.11 12.4 0.1 0.33 10.9 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KKF95148.1 - 0.14 12.5 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain HATPase_c PF02518.26 KKF95149.1 - 6e-28 97.6 0.2 1e-27 96.9 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKF95149.1 - 1e-18 67.1 0.4 3.3e-17 62.3 0.0 2.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KKF95149.1 - 5.2e-10 39.5 0.1 1.4e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Sipho_Gp157 PF05565.11 KKF95149.1 - 0.018 15.1 0.2 0.032 14.2 0.2 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Amidase PF01425.21 KKF95150.1 - 2.4e-76 257.5 0.0 1e-57 196.1 0.0 2.1 1 1 1 2 2 2 2 Amidase DUF1776 PF08643.10 KKF95151.1 - 4.7e-102 341.3 0.0 5.9e-102 341.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KKF95151.1 - 0.012 15.0 0.0 0.055 12.9 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Vps53_N PF04100.12 KKF95152.1 - 1.9e-92 310.2 1.1 3.2e-92 309.4 1.1 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal Pyr_redox_2 PF07992.14 KKF95152.1 - 1.1e-47 162.7 0.1 1.9e-47 161.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKF95152.1 - 3.3e-17 62.7 0.1 1.5e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKF95152.1 - 4.8e-14 52.7 1.2 7.1e-13 48.9 0.2 3.3 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KKF95152.1 - 0.0013 19.2 0.0 0.0072 16.7 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KKF95152.1 - 0.0019 18.4 0.2 0.36 11.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Vps54_N PF10475.9 KKF95152.1 - 0.0081 15.5 4.8 0.014 14.7 4.8 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex PsbU PF06514.11 KKF95152.1 - 0.043 13.8 0.0 0.23 11.5 0.0 2.3 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) Thi4 PF01946.17 KKF95152.1 - 0.061 12.5 0.1 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KKF95152.1 - 0.11 11.6 0.1 16 4.5 0.1 3.2 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF5082 PF16888.5 KKF95152.1 - 0.12 12.6 0.8 0.26 11.6 0.3 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) FokI_N PF02981.15 KKF95152.1 - 0.16 12.2 0.1 0.32 11.2 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain Uds1 PF15456.6 KKF95153.1 - 4.6e-21 75.3 4.9 4.6e-21 75.3 4.9 3.7 5 0 0 5 5 5 1 Up-regulated During Septation PEARLI-4 PF05278.12 KKF95153.1 - 0.14 11.7 0.6 0.31 10.6 0.6 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Kinesin PF00225.23 KKF95154.1 - 1.1e-110 369.6 0.0 2.4e-110 368.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain SNF2_N PF00176.23 KKF95154.1 - 3.5e-51 174.0 0.1 1.2e-50 172.3 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF3694 PF12473.8 KKF95154.1 - 1.9e-46 158.5 0.0 6.4e-46 156.8 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KKF95154.1 - 6.7e-35 120.9 14.7 1.8e-30 106.4 0.6 3.9 2 1 0 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 KKF95154.1 - 3.3e-24 85.5 0.2 1.4e-23 83.5 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Helicase_C PF00271.31 KKF95154.1 - 1.7e-19 70.2 0.0 1.4e-18 67.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 KKF95154.1 - 4.6e-15 55.5 0.1 1.5e-14 53.8 0.1 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal KIF1B PF12423.8 KKF95154.1 - 5.2e-07 30.0 0.1 2.9e-06 27.6 0.1 2.4 1 0 0 1 1 1 1 Kinesin protein 1B ERCC3_RAD25_C PF16203.5 KKF95154.1 - 3.8e-06 26.3 0.0 1.1e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KKF95154.1 - 8.7e-06 25.8 0.0 4e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKF95154.1 - 0.00055 19.8 0.0 0.0042 16.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase PH PF00169.29 KKF95154.1 - 0.032 14.7 0.0 18 5.9 0.1 2.8 2 0 0 2 2 2 0 PH domain AAA_34 PF13872.6 KKF95154.1 - 0.064 12.1 0.4 11 4.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 PRR18 PF15671.5 KKF95154.1 - 2 8.2 7.2 0.26 11.2 0.7 2.3 2 0 0 2 2 2 0 Proline-rich protein family 18 Methyltransf_23 PF13489.6 KKF95155.1 - 3.3e-05 23.8 0.0 0.00042 20.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF95155.1 - 4.4e-05 24.1 0.1 0.00021 21.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKF95155.1 - 0.00013 21.0 0.0 0.00019 20.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 KKF95155.1 - 0.0004 21.0 0.0 0.022 15.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF95155.1 - 0.018 15.8 0.0 0.091 13.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain OB_NTP_bind PF07717.16 KKF95156.1 - 4.6e-21 75.0 0.0 1.4e-20 73.4 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KKF95156.1 - 7.1e-17 61.6 0.0 7.1e-17 61.6 0.0 3.1 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKF95156.1 - 4.9e-13 49.4 0.0 1.2e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKF95156.1 - 9e-07 28.8 0.1 2.2e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKF95156.1 - 5.6e-05 23.4 0.0 0.00021 21.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKF95156.1 - 0.00013 21.7 0.1 0.00026 20.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF95156.1 - 0.0024 18.2 0.1 0.0052 17.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KKF95156.1 - 0.0025 17.5 0.3 0.0058 16.3 0.3 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 KKF95156.1 - 0.0086 15.2 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 KKF95156.1 - 0.11 13.0 0.0 0.41 11.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KKF95156.1 - 0.26 10.9 0.8 2.6 7.6 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ADH_zinc_N PF00107.26 KKF95157.1 - 9.3e-11 41.8 0.3 1.6e-10 41.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKF95157.1 - 0.0018 19.3 0.1 0.0049 17.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PRELI PF04707.14 KKF95158.1 - 1.1e-39 135.8 0.2 1.3e-39 135.5 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family Raf1_HTH PF18579.1 KKF95158.1 - 0.069 12.8 0.2 0.35 10.6 0.0 2.2 2 1 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain GATase_3 PF07685.14 KKF95158.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ATP-synt PF00231.19 KKF95159.1 - 2.2e-78 263.8 3.7 2.7e-78 263.5 3.7 1.0 1 0 0 1 1 1 1 ATP synthase Gp58 PF07902.11 KKF95159.1 - 0.006 14.9 0.0 0.0087 14.4 0.0 1.2 1 0 0 1 1 1 1 gp58-like protein EspA PF03433.13 KKF95159.1 - 0.012 15.4 0.3 0.12 12.2 0.4 2.0 2 0 0 2 2 2 0 EspA-like secreted protein PK_C PF02887.16 KKF95159.1 - 0.042 14.1 2.1 0.69 10.2 0.9 2.7 2 1 0 2 2 2 0 Pyruvate kinase, alpha/beta domain Mod_r PF07200.13 KKF95159.1 - 0.14 12.2 0.9 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TAD2 PF18521.1 KKF95160.1 - 2.6 8.2 5.5 12 6.1 0.5 2.6 2 0 0 2 2 2 0 Transactivation domain 2 Ribophorin_II PF05817.14 KKF95161.1 - 1.4e-29 103.1 0.0 1.7e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Fig1 PF12351.8 KKF95161.1 - 0.069 13.1 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Maf PF02545.14 KKF95162.1 - 5.9e-44 149.8 0.0 7.5e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein G-alpha PF00503.20 KKF95163.1 - 6.4e-96 321.6 0.1 7.3e-96 321.4 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KKF95163.1 - 3e-10 39.8 0.1 6.8e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Phosphorylase PF00343.20 KKF95164.1 - 0 1049.2 0.0 0 1048.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Got1 PF04178.12 KKF95165.1 - 8.3e-12 45.5 5.7 1e-11 45.2 5.7 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Actin PF00022.19 KKF95166.1 - 6.5e-49 166.6 0.0 2.7e-25 88.8 0.0 2.4 1 1 1 2 2 2 2 Actin DASH_Dad4 PF08650.10 KKF95166.1 - 4.7e-28 97.0 5.4 4.7e-28 97.0 5.4 2.2 2 0 0 2 2 2 1 DASH complex subunit Dad4 ATPgrasp_Ter PF15632.6 KKF95166.1 - 6.2 6.6 6.2 1.5 8.6 2.4 2.0 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Lin-8 PF03353.15 KKF95167.1 - 0.063 12.8 9.8 0.075 12.6 9.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Suf PF05843.14 KKF95167.1 - 0.36 10.8 5.5 0.38 10.7 5.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ATG11 PF10377.9 KKF95168.1 - 1.8e-45 154.1 0.4 1.8e-45 154.1 0.4 4.0 5 0 0 5 5 5 1 Autophagy-related protein 11 Spc7 PF08317.11 KKF95168.1 - 0.002 17.1 60.8 0.0088 15.0 18.1 3.8 2 1 1 3 3 3 3 Spc7 kinetochore protein PspA_IM30 PF04012.12 KKF95168.1 - 0.024 14.2 0.5 0.024 14.2 0.5 5.6 4 1 1 6 6 6 0 PspA/IM30 family FERM_f0 PF16511.5 KKF95168.1 - 0.071 13.4 0.1 0.47 10.8 0.0 2.4 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM HAP1_N PF04849.13 KKF95168.1 - 0.078 12.2 55.9 0.015 14.5 22.2 3.6 2 1 1 3 3 3 0 HAP1 N-terminal conserved region Filament PF00038.21 KKF95168.1 - 0.099 12.2 59.6 0.014 15.0 10.9 4.0 1 1 1 3 3 3 0 Intermediate filament protein DUF4407 PF14362.6 KKF95168.1 - 4.2 6.6 46.9 0.015 14.6 8.8 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 KKF95169.1 - 1.1e-25 90.2 1.7 6.2e-25 87.8 0.3 2.0 2 0 0 2 2 2 1 Centromere protein H (CENP-H) Ribosomal_S22 PF08136.11 KKF95169.1 - 0.038 14.4 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 30S ribosomal protein subunit S22 family HMG_box PF00505.19 KKF95170.1 - 2e-24 85.8 0.9 3e-24 85.2 0.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKF95170.1 - 1.2e-18 67.4 2.2 1.5e-18 67.1 1.6 1.4 1 1 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KKF95170.1 - 0.0028 18.2 2.9 0.0039 17.7 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 KKF95170.1 - 0.0042 17.0 0.6 0.0074 16.2 0.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.12 KKF95170.1 - 0.023 14.7 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain SIL1 PF16782.5 KKF95172.1 - 1.4e-06 27.8 0.0 3.1e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 Ribosomal_S19 PF00203.21 KKF95174.1 - 1.1e-33 114.9 0.3 1.5e-33 114.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 EpmC PF04315.12 KKF95174.1 - 0.21 11.3 0.0 10 5.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor P hydroxylase adh_short PF00106.25 KKF95175.1 - 0.0012 18.4 0.4 0.21 11.0 0.5 3.4 3 1 1 4 4 4 2 short chain dehydrogenase ArfGap PF01412.18 KKF95176.1 - 4.5e-15 55.7 0.1 6.9e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 KKF95176.1 - 0.042 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain DUF948 PF06103.11 KKF95177.1 - 3.1 8.1 4.7 11 6.4 0.0 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Ysc84 PF04366.12 KKF95178.1 - 2.8e-41 140.3 1.2 4.7e-41 139.5 0.3 1.8 2 0 0 2 2 2 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KKF95178.1 - 3e-14 52.3 0.2 1.1e-13 50.5 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KKF95178.1 - 1.6e-13 50.1 0.0 3.2e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KKF95178.1 - 1.2e-11 44.2 0.0 2.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 KKF95178.1 - 0.018 14.8 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) DUF21 PF01595.20 KKF95179.1 - 1.9e-28 99.3 0.0 3.1e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KKF95179.1 - 1.4e-05 25.4 0.9 0.004 17.6 0.0 3.2 3 0 0 3 3 3 2 CBS domain Glyoxalase PF00903.25 KKF95180.1 - 1.7e-33 115.6 0.0 1.3e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KKF95180.1 - 4.8e-14 52.5 0.1 1.8e-06 28.2 0.0 3.3 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KKF95180.1 - 1e-05 25.7 0.0 0.13 12.4 0.0 3.0 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KKF95180.1 - 0.00028 21.7 0.0 1.1 10.1 0.0 2.4 2 1 0 2 2 2 2 Glyoxalase-like domain MoaF PF10703.9 KKF95180.1 - 0.00075 19.4 0.1 0.35 10.8 0.0 2.8 2 1 1 3 3 3 1 MoaF N-terminal domain Glyoxalase_2 PF12681.7 KKF95180.1 - 0.00091 19.2 0.0 2.5 8.0 0.0 3.3 3 0 0 3 3 3 1 Glyoxalase-like domain DUF1338 PF07063.13 KKF95180.1 - 0.02 14.1 0.0 11 5.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1338) NIL PF09383.10 KKF95180.1 - 0.031 14.1 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 NIL domain TRI9 PF08195.11 KKF95180.1 - 0.04 13.8 0.1 11 5.9 0.0 2.3 2 0 0 2 2 2 0 TRI9 protein HTH_54 PF18607.1 KKF95180.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 ParA helix turn helix domain zinc_ribbon_11 PF11682.8 KKF95180.1 - 0.12 12.4 0.2 0.52 10.3 0.1 1.9 2 0 0 2 2 2 0 Probable zinc-ribbon SelR PF01641.18 KKF95181.1 - 2e-50 169.9 0.1 2.3e-50 169.7 0.1 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 KKF95181.1 - 0.013 15.7 0.1 0.023 14.9 0.1 1.5 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 KKF95181.1 - 0.025 14.3 0.1 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein MCM_OB PF17207.3 KKF95181.1 - 0.14 12.0 0.2 0.22 11.3 0.0 1.4 2 0 0 2 2 2 0 MCM OB domain DZR PF12773.7 KKF95181.1 - 0.26 11.3 3.8 4.4 7.4 4.0 2.3 1 1 1 2 2 2 0 Double zinc ribbon ARID PF01388.21 KKF95182.1 - 2.7e-16 60.0 0.0 6.4e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DevR PF01905.16 KKF95182.1 - 0.03 13.4 0.1 0.081 12.0 0.1 1.6 2 0 0 2 2 2 0 CRISPR-associated negative auto-regulator DevR/Csa2 RFX_DNA_binding PF02257.15 KKF95182.1 - 0.083 13.5 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Rootletin PF15035.6 KKF95182.1 - 0.13 12.3 0.2 0.26 11.3 0.2 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion adh_short_C2 PF13561.6 KKF95183.1 - 4.3e-62 209.7 0.6 5.5e-62 209.4 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKF95183.1 - 8.3e-51 172.2 0.5 1.2e-50 171.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKF95183.1 - 8.1e-12 45.4 0.3 1.3e-11 44.8 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKF95183.1 - 0.00029 20.4 0.0 0.00098 18.7 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKF95183.1 - 0.0066 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KKF95183.1 - 0.012 16.3 0.1 0.032 14.9 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.12 KKF95184.1 - 1.8e-26 92.2 1.9 3e-26 91.5 1.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKF95184.1 - 3.7e-12 46.3 0.0 6.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKF95184.1 - 6e-05 22.4 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KKF95184.1 - 0.001 18.5 0.2 0.0018 17.7 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.19 KKF95184.1 - 0.12 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase KH_1 PF00013.29 KKF95185.1 - 1.4e-92 303.5 28.8 5.3e-13 48.6 0.0 14.2 14 1 0 14 14 14 10 KH domain SLS PF14611.6 KKF95185.1 - 3.5e-14 53.2 5.9 0.002 18.0 0.0 6.9 5 1 3 8 8 8 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KKF95185.1 - 9.1e-10 38.2 19.6 0.23 11.3 0.2 7.4 6 1 0 7 7 7 4 KH domain BMC PF00936.19 KKF95185.1 - 0.012 15.6 2.2 93 3.1 0.2 4.8 4 0 0 4 4 4 0 BMC domain KH_4 PF13083.6 KKF95185.1 - 0.012 15.5 3.8 2.2 8.2 0.0 4.9 6 0 0 6 6 6 0 KH domain KH_5 PF13184.6 KKF95185.1 - 0.083 13.0 9.6 22 5.2 0.0 6.5 7 1 0 7 7 7 0 NusA-like KH domain HATPase_c_3 PF13589.6 KKF95186.1 - 1.7e-12 47.3 0.1 4.1e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KKF95186.1 - 1.5e-09 37.6 0.0 4.7e-09 35.9 0.0 1.9 2 1 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KKF95186.1 - 1.3e-07 32.1 0.1 3.4e-07 30.8 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UPF0147 PF03685.13 KKF95186.1 - 0.19 11.8 2.5 2 8.6 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) MutL_C PF08676.11 KKF95187.1 - 3.1e-19 69.2 3.3 2.5e-16 59.7 0.3 2.9 2 1 1 3 3 3 2 MutL C terminal dimerisation domain PIEZO PF15917.5 KKF95187.1 - 0.76 9.2 2.5 1.3 8.4 2.5 1.3 1 0 0 1 1 1 0 Piezo NUP50 PF08911.11 KKF95187.1 - 2.7 8.7 8.1 5 7.9 4.2 2.6 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) RSN1_7TM PF02714.15 KKF95188.1 - 5.3e-86 288.3 26.0 5.3e-86 288.3 26.0 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKF95188.1 - 2.8e-44 150.6 0.7 2.8e-44 150.6 0.7 2.7 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKF95188.1 - 5.6e-35 121.1 0.0 7.9e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KKF95188.1 - 8.7e-29 99.6 0.6 2.1e-28 98.3 0.2 1.9 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 KKF95188.1 - 0.044 13.6 0.2 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IU_nuc_hydro PF01156.19 KKF95189.1 - 1.2e-55 189.3 0.0 1.9e-55 188.6 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Rhomboid PF01694.22 KKF95193.1 - 2.1e-22 79.8 7.9 4e-22 78.8 7.9 1.4 1 0 0 1 1 1 1 Rhomboid family Pkr1 PF08636.10 KKF95194.1 - 3e-30 104.2 7.4 4e-30 103.8 7.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Orexin PF02072.15 KKF95194.1 - 0.75 9.7 2.6 6.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Prepro-orexin PGM_PMM_I PF02878.16 KKF95195.1 - 2.8e-33 114.6 0.0 4.1e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KKF95195.1 - 9e-25 87.1 0.0 1.5e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KKF95195.1 - 1.2e-15 58.0 0.0 2.7e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KKF95195.1 - 3e-06 27.3 0.0 6.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DSPn PF14671.6 KKF95196.1 - 1.7e-19 70.7 0.0 2.9e-17 63.4 0.0 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KKF95196.1 - 4.9e-17 62.0 0.0 1.8e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKF95196.1 - 1.3e-05 24.9 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KKF95196.1 - 0.056 13.6 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KKF95196.1 - 0.071 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KKF95196.1 - 0.12 12.0 0.1 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family Pcc1 PF09341.10 KKF95197.1 - 4.3e-30 103.7 1.6 6e-30 103.2 1.6 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 HLH PF00010.26 KKF95198.1 - 9e-16 57.6 0.0 9e-16 57.6 0.0 2.5 4 0 0 4 4 4 1 Helix-loop-helix DNA-binding domain GAS PF13851.6 KKF95198.1 - 0.12 11.7 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ECR1_N PF14382.6 KKF95200.1 - 1.9e-15 56.4 1.7 4.3e-15 55.2 1.7 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KKF95200.1 - 8.9e-05 22.8 0.5 0.00018 21.8 0.5 1.6 1 0 0 1 1 1 1 KH domain Aldedh PF00171.22 KKF95201.1 - 5.3e-79 265.9 0.0 6.6e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MRP-S28 PF10213.9 KKF95203.1 - 4.1e-47 159.7 0.2 6.7e-47 159.1 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein WD40 PF00400.32 KKF95204.1 - 1.2e-28 98.7 26.0 7.7e-06 26.6 0.1 10.0 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF95204.1 - 4.5e-13 49.3 3.7 0.0026 18.0 0.0 6.0 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF95204.1 - 0.00017 20.6 2.8 1.2 8.0 0.1 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KKF95204.1 - 0.00028 20.7 2.2 3 7.9 0.0 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KKF95204.1 - 0.002 17.5 0.8 11 5.2 0.0 4.0 4 0 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal NucS PF01939.16 KKF95204.1 - 0.05 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Endonuclease NucS HZS_alpha PF18582.1 KKF95204.1 - 0.09 13.3 0.1 2.5 8.6 0.0 3.1 2 1 0 3 3 3 0 Hydrazine synthase alpha subunit middle domain Hexapep_2 PF14602.6 KKF95205.1 - 1.9e-14 53.1 13.4 4.2e-09 36.0 5.4 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KKF95205.1 - 2.5e-13 49.2 11.9 1.1e-08 34.4 4.5 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KKF95205.1 - 1.5e-09 37.9 0.1 3.2e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase SANT_DAMP1_like PF16282.5 KKF95206.1 - 8.7e-31 106.0 1.0 1.7e-30 105.0 1.0 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DUF4637 PF15470.6 KKF95206.1 - 2.7 7.7 8.6 5.7 6.6 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2771 PF10969.8 KKF95207.1 - 0.2 11.7 0.0 9.6 6.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2771) DUF4885 PF16226.5 KKF95208.1 - 0.02 14.0 3.6 0.16 11.0 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4885) AF-4 PF05110.13 KKF95208.1 - 0.039 12.1 8.2 0.035 12.2 8.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein BUD22 PF09073.10 KKF95208.1 - 0.34 10.2 6.0 0.41 9.9 6.0 1.2 1 0 0 1 1 1 0 BUD22 NESP55 PF06390.12 KKF95208.1 - 3.9 7.0 7.5 9.2 5.8 7.5 1.7 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Ubiquitin_2 PF14560.6 KKF95209.1 - 0.029 14.8 0.0 0.078 13.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain AF-4 PF05110.13 KKF95209.1 - 0.11 10.5 3.1 0.12 10.5 3.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein YL1 PF05764.13 KKF95209.1 - 0.42 10.7 4.8 0.53 10.4 4.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein FOXO_KIX_bdg PF16675.5 KKF95209.1 - 4.2 7.8 7.2 23 5.4 2.9 2.8 1 1 1 2 2 2 0 KIX-binding domain of forkhead box O, CR2 IMUP PF15761.5 KKF95209.1 - 5.2 7.8 10.4 1 10.1 3.7 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein EMP24_GP25L PF01105.24 KKF95210.1 - 1.7e-50 171.5 0.0 1.9e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HXXSHH PF07586.11 KKF95210.1 - 0.013 15.1 0.2 0.018 14.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) CMV_US PF08001.11 KKF95211.1 - 0.046 13.0 0.0 0.047 13.0 0.0 1.0 1 0 0 1 1 1 0 CMV US GST_N_4 PF17172.4 KKF95212.1 - 6e-17 62.2 0.4 7.3e-16 58.7 0.4 2.4 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KKF95212.1 - 3.7e-09 37.0 0.7 5.9e-08 33.1 0.7 2.3 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Dioxygenase_C PF00775.21 KKF95212.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Dioxygenase SAM35 PF10806.8 KKF95212.1 - 0.17 12.2 0.1 1.3 9.3 0.0 2.1 1 1 1 2 2 2 0 SAM35, subunit of SAM coomplex CLTH PF10607.9 KKF95213.1 - 4.6e-23 81.8 0.2 6.7e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KKF95213.1 - 1.1e-22 80.4 0.2 1.8e-22 79.7 0.2 1.4 1 0 0 1 1 1 1 SPRY domain HAUS6_N PF14661.6 KKF95213.1 - 0.034 13.7 0.8 5.6 6.5 0.0 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus INO80_Ies4 PF08193.11 KKF95214.1 - 3.1e-54 184.5 15.7 3.1e-54 184.5 15.7 2.2 1 1 1 2 2 2 1 INO80 complex subunit Ies4 PT PF04886.12 KKF95215.1 - 4.8e-06 26.0 54.8 9e-06 25.1 27.9 3.3 3 0 0 3 3 3 2 PT repeat TspO_MBR PF03073.15 KKF95218.1 - 1.4e-36 125.6 4.3 1.7e-36 125.2 4.3 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF3546 PF12066.8 KKF95219.1 - 1.5e-26 92.8 5.3 1.5e-26 92.8 5.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 KKF95219.1 - 1.6e-11 43.8 0.1 3.6e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 KKF95219.1 - 2.9e-10 40.9 0.6 6.9e-10 39.6 0.6 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 PEP-utilisers_N PF05524.13 KKF95219.1 - 0.036 14.3 3.1 4.3 7.5 0.1 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal AAA PF00004.29 KKF95220.1 - 1.2e-40 138.9 0.0 2.2e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKF95220.1 - 5.5e-07 29.3 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KKF95220.1 - 0.0001 22.3 0.1 0.00043 20.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKF95220.1 - 0.00012 22.4 0.0 0.0069 16.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KKF95220.1 - 0.00035 20.7 0.0 0.00084 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KKF95220.1 - 0.00069 20.0 0.1 0.013 15.9 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KKF95220.1 - 0.002 17.4 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KKF95220.1 - 0.0076 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KKF95220.1 - 0.027 14.7 0.0 0.063 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKF95220.1 - 0.051 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKF95220.1 - 0.055 13.0 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KKF95220.1 - 0.058 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KKF95220.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KKF95220.1 - 0.1 12.3 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KKF95220.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KKF95220.1 - 0.14 12.0 0.3 11 5.9 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KKF95220.1 - 0.17 11.3 0.0 0.38 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 KKF95221.1 - 8.2e-151 503.0 16.3 9.2e-151 502.8 16.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DALR_2 PF09190.11 KKF95221.1 - 0.092 13.2 0.1 0.58 10.7 0.1 2.4 1 0 0 1 1 1 0 DALR domain Cytochrom_C1 PF02167.15 KKF95222.1 - 3.6e-71 239.4 0.0 4.7e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family TOM6p PF15184.6 KKF95222.1 - 0.039 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog DAHP_synth_1 PF00793.20 KKF95223.1 - 2.4e-101 338.2 0.0 3.9e-101 337.5 0.0 1.3 1 0 0 1 1 1 1 DAHP synthetase I family Rad21_Rec8_N PF04825.13 KKF95223.1 - 3.7e-37 126.9 0.0 7.9e-37 125.8 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KKF95223.1 - 4.4e-08 32.3 0.0 1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein COG4 PF08318.12 KKF95224.1 - 1.3e-120 402.5 0.0 1.8e-120 402.0 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein E1-E2_ATPase PF00122.20 KKF95224.1 - 7.5e-45 152.7 0.5 7.5e-45 152.7 0.5 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKF95224.1 - 1.4e-39 135.7 3.1 4.1e-39 134.2 3.1 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus SUA5 PF03481.13 KKF95224.1 - 7.4e-31 107.5 0.0 6.8e-30 104.4 0.0 2.6 3 0 0 3 3 3 1 Putative GTP-binding controlling metal-binding Sua5_yciO_yrdC PF01300.18 KKF95224.1 - 8.2e-31 106.9 0.0 2.1e-25 89.3 0.0 2.9 1 1 1 2 2 2 2 Telomere recombination Cation_ATPase_N PF00690.26 KKF95224.1 - 6.3e-20 70.6 0.0 1.5e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KKF95224.1 - 2.6e-19 70.4 2.6 1.8e-18 67.6 0.7 3.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKF95224.1 - 2.5e-12 46.7 0.0 7.1e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKF95224.1 - 3.7e-06 26.9 2.4 3.8e-06 26.8 0.8 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Clat_adaptor_s PF01217.20 KKF95225.1 - 6.4e-17 61.8 1.9 3.5e-16 59.4 1.9 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_S80 PF07230.11 KKF95225.1 - 0.026 12.8 0.1 0.064 11.5 0.0 1.6 2 0 0 2 2 2 0 Bacteriophage T4-like capsid assembly protein (Gp20) SH3_9 PF14604.6 KKF95226.1 - 1.2e-27 95.5 5.0 1e-13 50.9 0.4 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KKF95226.1 - 2.4e-27 94.2 4.7 4.3e-13 48.7 0.3 2.5 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 KKF95226.1 - 1.1e-16 60.7 0.0 2.2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KKF95226.1 - 7.4e-15 54.4 0.1 4.4e-07 29.5 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain Telomerase_RBD PF12009.8 KKF95227.1 - 1.7e-48 164.1 0.3 3.8e-48 163.0 0.3 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KKF95227.1 - 8e-12 45.1 0.0 7.5e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3781 PF12636.7 KKF95227.1 - 0.23 11.4 1.4 5.1 7.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) NACHT PF05729.12 KKF95228.1 - 8.3e-07 29.1 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain GvpD PF07088.11 KKF95228.1 - 0.077 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_19 PF13245.6 KKF95228.1 - 0.093 13.1 0.0 0.19 12.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKF95228.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SR-25 PF10500.9 KKF95229.1 - 0.0026 17.4 8.3 0.003 17.2 8.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein EGF_3 PF12947.7 KKF95229.1 - 0.02 15.1 2.9 0.02 15.1 2.9 2.9 3 1 0 3 3 3 0 EGF domain DUF2722 PF10846.8 KKF95229.1 - 0.033 13.2 2.6 0.037 13.0 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med19 PF10278.9 KKF95229.1 - 0.041 13.8 10.8 0.054 13.4 10.8 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 U79_P34 PF03064.16 KKF95229.1 - 0.081 12.3 8.8 0.096 12.0 8.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Tim54 PF11711.8 KKF95229.1 - 0.12 11.1 3.5 0.14 10.9 3.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 KKF95229.1 - 0.27 10.4 0.6 0.25 10.5 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_polI_A34 PF08208.11 KKF95229.1 - 0.44 10.6 14.1 0.57 10.2 14.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Presenilin PF01080.17 KKF95229.1 - 0.9 8.2 3.4 0.99 8.1 3.4 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 KKF95229.1 - 0.95 9.9 6.6 1.2 9.5 6.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 KKF95229.1 - 1.7 8.4 9.4 2.1 8.1 9.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 KKF95229.1 - 2.2 7.2 4.2 2.5 7.0 4.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MCM_bind PF09739.9 KKF95229.1 - 2.6 6.4 5.3 3.2 6.1 5.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RPN2_C PF18004.1 KKF95229.1 - 2.7 7.9 13.7 3.7 7.4 13.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sec62 PF03839.16 KKF95229.1 - 3.8 7.0 5.0 4.9 6.6 5.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Trypan_PARP PF05887.11 KKF95229.1 - 3.8 7.5 9.9 2.3 8.2 8.1 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PPTA PF01239.22 KKF95230.1 - 2.4e-25 87.4 12.3 1.8e-06 27.5 1.0 5.4 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat CN_hydrolase PF00795.22 KKF95230.1 - 9.6e-25 87.4 0.0 1.8e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KKF95230.1 - 5.2e-22 78.2 0.0 1.8e-21 76.3 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KKF95230.1 - 3.9e-05 23.5 0.0 0.00014 21.7 0.0 1.9 2 1 0 2 2 2 1 Asparagine synthase DUF3950 PF13132.6 KKF95230.1 - 0.089 12.6 0.1 24 4.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3950) Na_sulph_symp PF00939.19 KKF95231.1 - 4.6e-32 111.7 40.2 6.6e-32 111.2 40.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 KKF95231.1 - 1.2e-27 97.8 2.5 1.7e-27 97.4 2.5 1.1 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.16 KKF95231.1 - 1.2e-23 83.8 43.0 2.6e-23 82.7 41.5 2.2 2 1 1 3 3 3 2 Citrate transporter DUF373 PF04123.13 KKF95231.1 - 6.5 6.1 19.9 2 7.7 6.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF373) ABC_membrane PF00664.23 KKF95232.1 - 1e-83 281.2 23.4 7.1e-45 153.8 4.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKF95232.1 - 9.7e-64 214.0 0.0 1.6e-30 106.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKF95232.1 - 5.6e-16 58.6 0.0 1.9e-05 24.2 0.0 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKF95232.1 - 1.8e-08 34.6 2.2 0.3 10.8 0.0 4.5 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKF95232.1 - 5.1e-08 32.5 0.9 0.0077 16.0 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KKF95232.1 - 1.3e-06 28.8 0.7 0.081 13.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KKF95232.1 - 2.6e-06 27.9 3.8 0.0044 17.4 0.5 3.4 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKF95232.1 - 1e-05 25.5 0.0 0.21 11.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 KKF95232.1 - 1.7e-05 24.8 0.0 0.046 13.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KKF95232.1 - 0.00011 22.0 1.7 0.13 11.9 0.0 3.6 4 0 0 4 4 4 1 AAA domain DUF87 PF01935.17 KKF95232.1 - 0.00087 19.4 1.7 0.025 14.7 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 KKF95232.1 - 0.0014 19.1 5.5 7.7 6.9 0.8 5.1 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KKF95232.1 - 0.0015 18.7 1.9 4 7.7 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.6 KKF95232.1 - 0.0016 17.5 0.1 0.34 9.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_23 PF13476.6 KKF95232.1 - 0.002 18.6 7.6 0.78 10.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KKF95232.1 - 0.0026 17.3 0.0 2.6 7.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KKF95232.1 - 0.004 17.2 0.1 3.4 7.8 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_ATPase PF09818.9 KKF95232.1 - 0.0046 15.8 0.3 0.19 10.5 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_7 PF12775.7 KKF95232.1 - 0.0066 16.0 0.5 1 8.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 KKF95232.1 - 0.0076 16.0 0.0 1.8 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKF95232.1 - 0.015 15.9 0.1 3.2 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKF95232.1 - 0.021 14.1 0.0 7.8 5.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KKF95232.1 - 0.022 14.9 0.3 12 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKF95232.1 - 0.039 14.4 0.3 12 6.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KKF95232.1 - 0.071 12.3 0.0 5.7 6.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DEAD PF00270.29 KKF95232.1 - 0.11 12.3 0.0 0.68 9.7 0.0 2.3 2 1 0 2 2 2 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.17 KKF95232.1 - 0.15 11.9 1.7 8.9 6.0 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cytidylate_kin PF02224.18 KKF95232.1 - 0.31 10.7 4.0 7.3 6.3 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase Cad PF03596.13 KKF95232.1 - 0.83 9.5 4.2 0.92 9.4 0.9 2.6 3 0 0 3 3 3 0 Cadmium resistance transporter AAA_17 PF13207.6 KKF95232.1 - 1.6 9.1 3.8 11 6.4 0.2 3.1 3 0 0 3 3 2 0 AAA domain Pyr_redox_2 PF07992.14 KKF95233.1 - 2.9e-22 79.3 0.0 7e-22 78.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKF95233.1 - 7.5e-11 42.4 0.7 1.1e-08 35.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKF95233.1 - 0.0092 15.2 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KKF95233.1 - 0.031 14.7 0.2 0.25 11.8 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KKF95233.1 - 0.042 13.1 1.4 1.7 7.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KKF95233.1 - 0.044 13.0 0.7 0.52 9.5 0.3 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KKF95233.1 - 0.11 11.8 0.7 2.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KKF95233.1 - 0.14 11.1 0.1 0.14 11.1 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KKF95233.1 - 0.3 9.7 0.8 5 5.7 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein Acetyltransf_8 PF13523.6 KKF95234.1 - 2.7e-45 153.6 0.6 4.4e-45 152.9 0.6 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KKF95234.1 - 8.8e-18 64.3 50.4 6e-16 58.3 48.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKF95234.1 - 6.3e-08 31.5 13.3 1e-07 30.8 13.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acetyltransf_3 PF13302.7 KKF95234.1 - 0.12 13.0 0.1 0.28 11.8 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 KKF95235.1 - 1.4e-36 126.0 0.0 1.7e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKF95235.1 - 1.6e-13 51.4 0.0 2.9e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 KKF95235.1 - 0.15 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KKF95236.1 - 4.3e-71 239.7 0.0 1.8e-69 234.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KKF95236.1 - 2.3e-47 161.7 0.0 2.6e-32 112.1 0.0 3.3 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 KKF95236.1 - 1.8e-24 85.9 0.0 7.6e-12 45.4 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site PAPA-1 PF04795.12 KKF95237.1 - 2.2e-06 28.3 4.2 2.2e-06 28.3 4.2 2.7 3 1 1 4 4 4 1 PAPA-1-like conserved region DUF3958 PF13125.6 KKF95237.1 - 0.29 11.3 3.0 0.45 10.7 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Pex14_N PF04695.13 KKF95238.1 - 6.7e-29 101.6 1.2 6.7e-29 101.6 1.2 1.6 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4714 PF15833.5 KKF95239.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) RVT_2 PF07727.14 KKF95240.1 - 4.6e-49 167.3 0.0 6.9e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SDA1 PF05285.12 KKF95240.1 - 0.47 9.8 10.9 0.73 9.2 10.9 1.2 1 0 0 1 1 1 0 SDA1 Retrotran_gag_2 PF14223.6 KKF95241.1 - 3.6e-06 26.7 0.2 3.6e-06 26.7 0.2 2.0 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KKF95241.1 - 0.11 12.6 0.8 0.19 11.9 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KKF95241.1 - 0.12 12.2 2.9 0.43 10.4 1.2 2.6 3 0 0 3 3 3 0 Zinc knuckle zf-C2H2_10 PF16588.5 KKF95241.1 - 0.56 10.0 4.6 0.9 9.3 4.6 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger Pkinase PF00069.25 KKF95242.1 - 9e-08 31.8 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95242.1 - 1e-05 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M78 PF06114.13 KKF95243.1 - 0.049 13.6 0.2 0.08 12.9 0.1 1.5 1 1 0 1 1 1 0 IrrE N-terminal-like domain DUF2423 PF10338.9 KKF95244.1 - 6.7e-17 61.4 2.2 6.7e-17 61.4 2.2 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) RRM_1 PF00076.22 KKF95245.1 - 6.7e-60 198.8 0.3 5.4e-17 61.4 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKF95245.1 - 8.7e-05 22.6 0.3 1.4 9.1 0.0 3.9 3 0 0 3 3 3 2 RNA recognition motif RRM_Rrp7 PF17799.1 KKF95245.1 - 0.0011 18.7 9.1 0.075 12.8 0.1 4.3 3 2 2 5 5 5 2 Rrp7 RRM-like N-terminal domain Cnd3 PF12719.7 KKF95246.1 - 1.5e-80 270.6 4.8 1.1e-78 264.4 3.0 3.4 2 2 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KKF95246.1 - 1.4e-09 38.2 11.5 3.8e-06 27.2 1.5 4.8 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 KKF95246.1 - 3.7e-07 29.9 9.5 0.34 11.3 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KKF95246.1 - 4.4e-06 26.8 2.3 0.089 12.8 0.1 4.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KKF95246.1 - 2.9 8.5 10.8 1.4 9.5 1.0 5.0 4 2 2 6 6 6 0 HEAT-like repeat PBD PF00786.28 KKF95248.1 - 0.0069 16.7 0.3 0.018 15.4 0.0 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain POB3_N PF17292.2 KKF95249.1 - 7.7e-29 100.0 1.0 1.5e-26 92.7 0.1 3.0 3 0 0 3 3 3 2 POB3-like N-terminal PH domain SSrecog PF03531.14 KKF95249.1 - 1e-28 99.0 0.2 5.6e-28 96.6 0.0 2.4 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KKF95249.1 - 2.2e-22 79.3 0.0 3.5e-21 75.4 0.1 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like tRNA_bind_4 PF18490.1 KKF95249.1 - 0.091 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 tRNA-binding domain AMP-binding PF00501.28 KKF95250.1 - 3.4e-71 240.0 0.0 4.2e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKF95250.1 - 7.8e-20 71.6 0.0 2.2e-19 70.2 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EVE PF01878.18 KKF95251.1 - 4.7e-43 146.7 0.0 5.3e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 EVE domain Glyco_hydro_1 PF00232.18 KKF95252.1 - 3e-120 401.7 0.1 1.8e-60 204.6 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 NmrA PF05368.13 KKF95252.1 - 3.3e-26 92.3 0.0 5.5e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKF95252.1 - 9.6e-08 32.1 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding AID PF18767.1 KKF95252.1 - 0.014 15.4 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Activation induced deaminase Epimerase PF01370.21 KKF95252.1 - 0.038 13.4 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2052 PF09747.9 KKF95253.1 - 0.01 16.0 7.8 0.01 16.0 7.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TP53IP5 PF15331.6 KKF95253.1 - 0.07 13.3 3.4 0.12 12.6 3.4 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PI3K_1B_p101 PF10486.9 KKF95253.1 - 0.17 9.6 1.2 0.23 9.2 1.2 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CPSF100_C PF13299.6 KKF95253.1 - 0.43 10.8 9.5 0.059 13.6 3.6 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Apt1 PF10351.9 KKF95253.1 - 0.56 9.0 6.6 0.65 8.8 6.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spt5_N PF11942.8 KKF95253.1 - 0.66 11.0 18.4 0.39 11.7 7.4 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ebp2 PF05890.12 KKF95253.1 - 1.9 8.0 15.5 1.2 8.6 14.2 1.3 1 1 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 Hid1 PF12722.7 KKF95253.1 - 3.1 5.8 5.5 3.2 5.8 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 KKF95253.1 - 3.4 5.8 19.4 0.15 10.2 11.3 1.9 2 0 0 2 2 2 0 Nop14-like family RR_TM4-6 PF06459.12 KKF95253.1 - 9.3 6.0 15.6 0.37 10.6 8.5 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF924 PF06041.11 KKF95254.1 - 4.3e-40 137.8 0.0 1e-39 136.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Erf4 PF10256.9 KKF95255.1 - 8.5e-36 122.6 0.0 1.1e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family SSB PF00436.25 KKF95256.1 - 1.7e-09 37.7 0.0 3.1e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Single-strand binding protein family GSH_synth_ATP PF03917.17 KKF95257.1 - 6.8e-131 436.5 0.0 7.7e-131 436.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KKF95257.1 - 4e-33 113.9 0.2 7.7e-33 113.0 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Cu_bind_like PF02298.17 KKF95258.1 - 0.002 18.1 0.0 0.0054 16.7 0.0 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain Ank_2 PF12796.7 KKF95259.1 - 1.1e-11 45.1 2.1 8.3e-09 35.9 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKF95259.1 - 4.1e-11 43.2 2.8 0.00068 20.2 0.0 5.9 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKF95259.1 - 1.3e-09 38.1 2.1 5.6e-06 26.5 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KKF95259.1 - 1.6e-07 31.4 1.4 0.0019 18.5 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KKF95259.1 - 1.8e-06 27.8 1.3 0.0019 18.5 0.0 5.2 5 2 1 6 6 6 1 Ankyrin repeat Abhydrolase_1 PF00561.20 KKF95260.1 - 4.5e-10 39.6 0.0 3.2e-09 36.8 0.0 2.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold Ndr PF03096.14 KKF95260.1 - 5e-07 28.7 0.0 6.9e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.7 KKF95260.1 - 7.6e-07 30.0 0.4 8.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKF95260.1 - 8.8e-07 28.4 0.0 4.5e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KKF95260.1 - 0.026 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Mcl1_mid PF12341.8 KKF95261.1 - 2.1e-95 319.5 0.0 1e-94 317.2 0.0 2.1 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 KKF95261.1 - 3.9e-12 46.3 0.0 1.4e-05 25.3 0.0 5.9 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKF95261.1 - 6.3e-12 45.8 2.8 7.8e-07 29.7 0.2 6.2 6 1 0 6 6 6 1 WD domain, G-beta repeat eIF2A PF08662.11 KKF95261.1 - 0.00033 20.6 0.0 0.021 14.7 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KKF95261.1 - 0.031 14.2 2.3 0.55 10.2 0.1 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KKF95261.1 - 0.057 12.4 0.0 3.8 6.4 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KKF95261.1 - 0.15 11.1 0.0 0.51 9.3 0.0 1.7 1 1 1 2 2 2 0 Coatomer WD associated region TFIIIC_delta PF12657.7 KKF95261.1 - 0.19 11.6 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 KKF95261.1 - 0.19 9.6 0.2 0.81 7.6 0.1 1.6 1 1 1 2 2 2 0 IKI3 family P21-Arc PF04062.14 KKF95262.1 - 7.2e-71 237.8 0.0 9e-71 237.5 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 KKF95263.1 - 3.9e-105 351.3 0.0 6.9e-105 350.4 0.0 1.4 1 1 0 1 1 1 1 Gcd10p family ABC2_membrane PF01061.24 KKF95265.1 - 1e-84 283.1 45.5 1.5e-49 168.3 11.8 3.6 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KKF95265.1 - 1.1e-38 132.8 0.0 5e-18 65.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKF95265.1 - 7.5e-21 73.8 0.2 3.5e-18 65.3 0.1 2.8 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KKF95265.1 - 1.8e-10 40.4 31.8 6.5e-07 28.8 14.4 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KKF95265.1 - 1.3e-05 25.2 0.1 0.021 14.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KKF95265.1 - 2.2e-05 25.0 0.0 0.12 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KKF95265.1 - 2.3e-05 24.7 0.2 0.51 10.6 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KKF95265.1 - 3.7e-05 24.2 0.1 0.083 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 KKF95265.1 - 8e-05 22.9 0.2 0.27 11.5 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KKF95265.1 - 8.8e-05 22.2 0.1 0.004 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KKF95265.1 - 0.00062 19.8 0.2 0.3 11.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KKF95265.1 - 0.00068 19.3 0.6 0.1 12.3 0.2 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KKF95265.1 - 0.0056 16.4 0.5 3.5 7.3 0.7 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KKF95265.1 - 0.01 16.0 0.0 0.47 10.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KKF95265.1 - 0.017 14.7 0.7 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KKF95265.1 - 0.019 14.7 0.4 5 6.9 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 KKF95265.1 - 0.022 14.1 0.0 0.7 9.2 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA PF00004.29 KKF95265.1 - 0.039 14.4 0.1 17 5.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_trans_N PF14510.6 KKF95265.1 - 0.056 14.1 0.1 0.16 12.6 0.1 1.8 1 0 0 1 1 1 0 ABC-transporter N-terminal AAA_21 PF13304.6 KKF95265.1 - 0.21 11.3 0.0 20 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system BRO1 PF03097.18 KKF95266.1 - 1.6e-118 395.9 0.0 3.4e-117 391.6 0.0 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KKF95266.1 - 4.3e-67 226.5 6.3 8e-67 225.6 6.3 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV ParB_C PF18064.1 KKF95266.1 - 1.9 8.7 4.8 2.8 8.2 1.2 2.8 2 1 0 2 2 2 0 Centromere-binding protein ParB C-terminal Ysc84 PF04366.12 KKF95267.1 - 1.2e-41 141.4 0.4 2.2e-41 140.6 0.4 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator FSH1 PF03959.13 KKF95268.1 - 3.5e-30 105.3 0.0 4.6e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KKF95268.1 - 0.00046 20.9 1.0 0.00059 20.5 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKF95268.1 - 0.035 13.9 1.4 0.19 11.5 0.3 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Meth_synt_2 PF01717.18 KKF95269.1 - 4.6e-153 509.2 0.0 1.1e-147 491.5 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KKF95269.1 - 1.5e-118 395.9 0.0 1.3e-111 373.0 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain VbhA PF18495.1 KKF95269.1 - 0.075 12.9 0.3 6.5 6.7 0.0 2.7 2 0 0 2 2 2 0 Antitoxin VbhA Inositol_P PF00459.25 KKF95270.1 - 9.3e-33 113.9 0.0 2.3e-32 112.6 0.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 KKF95271.1 - 4e-10 39.1 27.7 4e-10 39.1 27.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KKF95271.1 - 0.07 12.6 13.4 0.021 14.3 7.2 2.7 2 1 0 2 2 2 0 Nodulin-like ABC2_membrane_5 PF13346.6 KKF95271.1 - 2.4 7.7 14.6 8.3 5.9 3.7 3.1 2 1 0 2 2 2 0 ABC-2 family transporter protein Kinesin PF00225.23 KKF95272.1 - 1.1e-74 251.4 0.6 5e-74 249.2 0.6 2.2 1 0 0 1 1 1 1 Kinesin motor domain RNase_H PF00075.24 KKF95273.1 - 3e-07 30.7 0.1 5e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 RNase H CitT PF12431.8 KKF95273.1 - 0.18 12.2 0.1 0.4 11.1 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator NmrA PF05368.13 KKF95274.1 - 1.5e-23 83.6 0.2 1.9e-23 83.3 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKF95274.1 - 1.3e-17 64.3 0.0 2.1e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKF95274.1 - 0.00015 21.3 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KKF95274.1 - 0.0019 18.3 0.2 0.0034 17.5 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.19 KKF95274.1 - 0.013 16.2 2.7 0.23 12.2 0.7 2.5 2 1 0 2 2 2 0 CoA binding domain NAD_binding_2 PF03446.15 KKF95274.1 - 0.017 15.3 0.1 0.043 14.0 0.1 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 KKF95274.1 - 0.029 13.5 0.1 0.041 13.0 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TrbI_Ftype PF09677.10 KKF95274.1 - 0.089 13.1 0.2 0.15 12.4 0.2 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Sugar_tr PF00083.24 KKF95275.1 - 1.9e-88 297.3 17.2 2.5e-88 296.9 17.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF95275.1 - 2.5e-14 53.0 35.2 7.6e-09 35.0 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cnn_1N PF07989.11 KKF95276.1 - 1.1e-21 76.8 9.0 1.1e-21 76.8 9.0 11.2 7 1 6 13 13 13 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KKF95276.1 - 1e-07 32.1 11.7 1e-07 32.1 11.7 13.4 15 1 1 16 16 16 2 Micro-tubular organiser Mto1 C-term Mto2-binding region GP41 PF00517.17 KKF95276.1 - 1.7 8.5 5.2 1.9 8.4 0.0 3.5 3 1 1 4 4 4 0 Retroviral envelope protein DUF1996 PF09362.10 KKF95277.1 - 3e-45 155.1 0.1 3.5e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) E1_dh PF00676.20 KKF95279.1 - 1.3e-87 293.5 0.0 1.6e-87 293.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KKF95279.1 - 0.00043 20.1 0.5 0.004 16.9 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RNA_pol_Rpb6 PF01192.22 KKF95279.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb6 DXP_synthase_N PF13292.6 KKF95279.1 - 0.17 11.1 0.0 0.42 9.8 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase zf-RING_4 PF14570.6 KKF95281.1 - 2.3e-15 56.1 12.3 2.9e-14 52.6 9.7 3.0 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KKF95281.1 - 1.5e-09 37.5 0.1 1.7e-08 34.2 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KKF95281.1 - 0.00048 19.7 0.2 0.0016 18.1 0.0 1.9 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated zf-C3HC4_3 PF13920.6 KKF95281.1 - 0.00085 19.1 6.8 0.013 15.3 6.8 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKF95281.1 - 0.012 15.4 5.1 0.4 10.6 1.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Rtf2 PF04641.12 KKF95281.1 - 0.014 14.8 0.6 0.014 14.8 0.6 3.5 4 0 0 4 4 4 0 Rtf2 RING-finger Nup35_RRM_2 PF14605.6 KKF95281.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-ANAPC11 PF12861.7 KKF95281.1 - 0.051 13.6 0.2 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 KKF95281.1 - 0.064 13.1 0.5 5.4 6.9 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_2 PF13639.6 KKF95281.1 - 0.39 11.1 9.4 3.7 8.0 9.4 2.3 1 1 0 1 1 1 0 Ring finger domain FYVE PF01363.21 KKF95281.1 - 2 8.6 4.7 16 5.8 4.6 2.4 1 1 0 1 1 1 0 FYVE zinc finger Complex1_30kDa PF00329.19 KKF95282.1 - 1.3e-45 155.0 0.0 1.7e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit HECT PF00632.25 KKF95283.1 - 1.3e-59 202.2 0.0 6.1e-55 186.9 0.0 2.3 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) Ubie_methyltran PF01209.18 KKF95284.1 - 8.9e-79 264.1 0.0 1.1e-78 263.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KKF95284.1 - 1e-15 58.2 0.0 3e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF95284.1 - 1.1e-13 51.6 0.0 2.8e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF95284.1 - 1.9e-11 43.9 0.0 3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF95284.1 - 8.4e-11 42.5 0.0 1.4e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF95284.1 - 2.5e-07 30.7 0.0 3.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KKF95284.1 - 0.0028 17.5 0.0 0.0063 16.4 0.0 1.6 2 0 0 2 2 2 1 Hypothetical methyltransferase ADH_zinc_N PF00107.26 KKF95284.1 - 0.099 12.6 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF2433 PF10360.9 KKF95285.1 - 1e-49 167.8 0.1 1.7e-49 167.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 KKF95285.1 - 0.0001 22.9 0.0 0.00057 20.4 0.0 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKF95285.1 - 0.002 18.4 0.0 0.0069 16.6 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Zds_C PF08632.10 KKF95286.1 - 8.1e-28 95.9 0.9 8.1e-28 95.9 0.9 1.7 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Sec3_C PF09763.9 KKF95287.1 - 4.4e-199 663.3 10.1 5.6e-199 663.0 10.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Vps52 PF04129.12 KKF95287.1 - 0.00044 19.1 0.7 0.00044 19.1 0.7 1.9 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C_2 PF15278.6 KKF95287.1 - 0.014 15.7 0.7 0.046 14.1 0.1 2.2 2 0 0 2 2 2 0 Sec3 exocyst complex subunit BAR_3 PF16746.5 KKF95287.1 - 0.024 14.3 0.2 0.024 14.3 0.2 3.1 3 0 0 3 3 3 0 BAR domain of APPL family PH_10 PF15411.6 KKF95289.1 - 1.6e-29 102.6 0.1 2.7e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KKF95289.1 - 9.7e-14 52.0 0.0 1.6e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KKF95289.1 - 1.5e-09 38.0 0.3 1e-08 35.3 0.1 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain DUF1147 PF06615.11 KKF95289.1 - 0.17 12.0 0.5 0.35 11.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) Cyclin PF08613.11 KKF95290.1 - 1.2e-32 113.5 0.0 2.3e-32 112.6 0.0 1.4 1 1 0 1 1 1 1 Cyclin PET117 PF15786.5 KKF95290.1 - 8 6.8 12.5 16 5.9 12.5 1.5 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial HAUS-augmin3 PF14932.6 KKF95292.1 - 0.00026 20.6 7.0 0.00026 20.6 7.0 3.0 3 1 1 4 4 4 1 HAUS augmin-like complex subunit 3 DUF2935 PF11155.8 KKF95292.1 - 0.24 11.7 3.1 1.9 8.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) Golgin_A5 PF09787.9 KKF95292.1 - 7.3 6.0 15.7 18 4.7 15.3 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF1664 PF07889.12 KKF95292.1 - 7.6 6.6 5.7 19 5.3 0.7 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) Rotamase PF00639.21 KKF95293.1 - 1.7e-20 73.8 0.0 2.6e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KKF95293.1 - 8.9e-15 55.3 0.0 1.3e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KKF95293.1 - 1.1e-06 28.7 0.7 2.1e-06 27.7 0.2 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KKF95293.1 - 0.0012 19.7 0.0 0.0016 19.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain TFIIS_C PF01096.18 KKF95294.1 - 1.9e-16 59.6 12.6 8.7e-16 57.5 4.4 3.0 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KKF95294.1 - 1.1e-07 31.6 1.1 1.1e-07 31.6 1.1 2.3 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.6 KKF95294.1 - 0.076 13.4 2.6 0.076 13.4 2.6 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 KKF95294.1 - 0.15 12.1 15.2 0.075 13.1 2.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon Rpr2 PF04032.16 KKF95294.1 - 0.58 10.5 8.2 11 6.3 8.2 2.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain A2L_zn_ribbon PF08792.10 KKF95294.1 - 8.3 6.3 16.7 1.6 8.5 2.6 3.5 4 0 0 4 4 4 0 A2L zinc ribbon domain Ribosomal_L14 PF00238.19 KKF95295.1 - 5.8e-40 136.2 2.0 7.5e-40 135.8 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ACP_syn_III PF08545.10 KKF95295.1 - 0.06 13.2 0.1 0.34 10.8 0.0 2.0 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SET PF00856.28 KKF95296.1 - 2.5e-09 37.7 0.2 1e-08 35.8 0.2 2.0 1 1 0 1 1 1 1 SET domain FAM76 PF16046.5 KKF95296.1 - 0.019 14.3 0.7 0.019 14.3 0.7 2.2 2 0 0 2 2 2 0 FAM76 protein ATP-cone PF03477.16 KKF95297.1 - 0.015 15.9 0.0 0.045 14.3 0.0 1.8 1 0 0 1 1 1 0 ATP cone domain DUF4407 PF14362.6 KKF95297.1 - 9.2 5.5 9.1 12 5.1 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glycos_transf_3 PF00591.21 KKF95298.1 - 7.8e-63 212.4 0.0 1.1e-62 211.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KKF95298.1 - 1.9e-12 46.8 0.0 7.6e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Velvet PF11754.8 KKF95300.1 - 1.9e-44 152.5 66.3 3.8e-44 151.5 38.3 3.5 1 1 1 2 2 2 1 Velvet factor DUF2924 PF11149.8 KKF95300.1 - 0.29 11.5 0.1 0.29 11.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2924) Peptidase_S64 PF08192.11 KKF95300.1 - 2.3 6.6 21.0 3.2 6.1 21.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF3602 PF12223.8 KKF95301.1 - 1.7e-15 57.4 7.4 2.3e-12 47.4 2.6 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 KKF95301.1 - 0.32 10.6 3.6 1.9 8.1 0.0 2.7 1 1 2 3 3 3 0 GTP1/OBG URO-D PF01208.17 KKF95302.1 - 6.2e-127 423.5 0.0 7e-127 423.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Amidase PF01425.21 KKF95303.1 - 1.7e-68 231.6 0.0 2.7e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 Amidase Fib_alpha PF08702.10 KKF95305.1 - 0.011 16.0 5.4 0.068 13.3 5.4 2.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KKF95305.1 - 0.1 12.6 5.1 0.49 10.4 5.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 KKF95305.1 - 0.18 12.1 9.4 1 9.7 2.2 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF3915 PF13054.6 KKF95305.1 - 0.22 11.5 2.8 0.57 10.2 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Allexi_40kDa PF05549.11 KKF95305.1 - 0.49 9.9 3.0 1.7 8.1 3.0 1.9 1 0 0 1 1 1 0 Allexivirus 40kDa protein Csm1_N PF18504.1 KKF95305.1 - 2.3 8.6 9.8 0.95 9.9 1.0 4.2 2 1 0 2 2 2 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 KKF95305.1 - 2.5 5.9 5.1 7.5 4.3 5.1 1.8 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KxDL PF10241.9 KKF95305.1 - 3.7 7.9 5.7 3.2 8.1 2.5 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein Bacillus_HBL PF05791.11 KKF95305.1 - 8.6 6.1 8.6 17 5.1 1.9 2.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PKcGMP_CC PF16808.5 KKF95305.1 - 8.6 6.3 15.7 0.19 11.6 1.0 4.3 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UCR_TM PF02921.14 KKF95306.1 - 0.42 11.1 3.5 37 4.9 0.1 4.5 3 1 1 4 4 4 0 Ubiquinol cytochrome reductase transmembrane region Cullin PF00888.22 KKF95307.1 - 1e-19 70.6 0.0 1.9e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KKF95307.1 - 4.9e-19 68.6 0.1 3.6e-18 65.8 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 RESP18 PF14948.6 KKF95307.1 - 0.033 14.5 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 RESP18 domain PG_binding_2 PF08823.11 KKF95307.1 - 0.048 14.0 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Styelin PF17562.2 KKF95307.1 - 0.081 13.3 0.2 0.23 11.9 0.2 1.7 1 0 0 1 1 1 0 Styelin zf-C2H2 PF00096.26 KKF95308.1 - 0.0027 18.1 3.7 0.34 11.4 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKF95308.1 - 0.018 15.8 2.0 8.9 7.4 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKF95308.1 - 0.033 14.6 0.9 0.38 11.3 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double domain DHFR_1 PF00186.19 KKF95309.1 - 5.8e-28 97.6 0.0 2.7e-27 95.4 0.0 2.1 1 1 0 1 1 1 1 Dihydrofolate reductase ketoacyl-synt PF00109.26 KKF95310.1 - 2e-51 175.0 7.6 9.3e-51 172.8 2.8 2.5 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKF95310.1 - 7.4e-34 116.3 1.0 1.4e-33 115.4 1.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Ubiq_cyt_C_chap PF03981.12 KKF95310.1 - 1.7e-33 115.7 0.7 3.2e-33 114.8 0.7 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Thiolase_N PF00108.23 KKF95310.1 - 0.00016 21.1 3.1 0.0015 17.9 0.3 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain OPT PF03169.15 KKF95311.1 - 1.4e-181 605.3 47.8 1.6e-181 605.1 47.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.14 KKF95311.1 - 0.0044 17.1 0.2 0.014 15.4 0.2 1.9 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Biotin_lipoyl PF00364.22 KKF95312.1 - 3.2e-19 68.5 0.2 6.5e-19 67.6 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KKF95312.1 - 2.6e-06 27.6 0.0 1e-05 25.8 0.0 2.1 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KKF95312.1 - 1.1e-05 25.1 0.1 8.5e-05 22.3 0.0 2.4 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.6 KKF95312.1 - 0.0016 19.1 0.7 0.059 14.1 0.2 3.2 3 1 1 4 4 4 1 HlyD family secretion protein Med3 PF11593.8 KKF95312.1 - 4.6 6.3 6.0 7.2 5.7 6.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LRR_4 PF12799.7 KKF95314.1 - 0.00021 21.6 0.1 0.52 10.8 0.0 3.5 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKF95314.1 - 0.00041 20.1 0.0 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 KKF95314.1 - 0.27 10.7 1.4 0.27 10.7 0.1 1.5 2 0 0 2 2 2 0 Leucine-rich repeat EPL1 PF10513.9 KKF95315.1 - 8.3e-22 78.3 4.6 1.1e-21 77.9 0.0 3.3 3 1 0 3 3 3 1 Enhancer of polycomb-like Metallophos PF00149.28 KKF95316.1 - 1.5e-39 136.7 0.1 2.1e-39 136.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase G-gamma PF00631.22 KKF95317.1 - 1.3e-23 82.8 0.0 1.5e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 KKF95318.1 - 7.7e-10 39.2 0.5 7.2e-09 36.1 0.1 2.7 2 0 0 2 2 2 1 PCI domain MMR_HSR1_Xtn PF16897.5 KKF95319.1 - 4e-41 139.3 0.9 1.6e-40 137.4 0.6 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KKF95319.1 - 2.8e-22 78.5 0.1 5.6e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KKF95319.1 - 1.1e-21 77.0 0.0 7.3e-21 74.4 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKF95319.1 - 6.6e-10 38.7 0.1 3.9e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKF95319.1 - 0.0002 21.5 0.1 0.045 13.8 0.0 2.4 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 KKF95319.1 - 0.00035 20.2 0.1 10 5.6 0.0 4.0 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KKF95319.1 - 0.0064 15.5 0.2 0.023 13.7 0.1 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KKF95319.1 - 0.029 14.6 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KKF95319.1 - 0.04 13.8 0.9 5.2 6.9 0.1 2.8 3 1 0 3 3 3 0 RsgA GTPase AIG1 PF04548.16 KKF95319.1 - 0.06 12.7 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Arf PF00025.21 KKF95319.1 - 0.061 12.8 0.1 8.4 5.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.6 KKF95319.1 - 0.11 12.8 0.0 0.96 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKF95319.1 - 0.2 11.8 0.2 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain HTH_Tnp_Tc5 PF03221.16 KKF95320.1 - 8.9e-13 48.1 0.0 1.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 KKF95320.1 - 0.0053 16.5 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KKF95320.1 - 0.011 15.3 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_Crp_2 PF13545.6 KKF95320.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 KKF95320.1 - 0.17 11.8 0.0 0.53 10.3 0.0 1.8 1 0 0 1 1 1 0 MarR family NACHT_N PF17100.5 KKF95321.1 - 1.1e-60 205.2 0.5 1.1e-60 205.2 0.5 2.2 3 0 0 3 3 3 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KKF95321.1 - 1.6e-19 70.4 0.0 4.9e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 KKF95321.1 - 0.002 18.9 4.5 0.0083 17.0 0.1 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF95321.1 - 0.0052 17.1 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_11 PF13086.6 KKF95321.1 - 0.013 15.3 1.7 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rx_N PF18052.1 KKF95321.1 - 0.031 14.6 1.9 0.15 12.4 1.9 2.3 1 0 0 1 1 1 0 Rx N-terminal domain AAA_22 PF13401.6 KKF95321.1 - 0.12 12.6 0.0 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KKF95321.1 - 0.15 12.4 0.0 0.54 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DASH_Spc34 PF08657.10 KKF95321.1 - 0.19 11.5 3.8 0.33 10.7 3.8 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF5365 PF17326.2 KKF95321.1 - 0.36 11.3 1.7 1.9 8.9 0.9 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5365) BST2 PF16716.5 KKF95321.1 - 4 8.1 11.6 1.4 9.5 7.8 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 APH PF01636.23 KKF95322.1 - 4.9e-07 29.9 0.0 1.2e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KKF95322.1 - 0.023 14.0 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Fructosamin_kin PF03881.14 KKF95322.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase MFS_1 PF07690.16 KKF95323.1 - 8e-14 51.3 44.5 5.8e-12 45.2 42.7 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KKF95323.1 - 8.6e-09 34.4 19.2 1.3e-08 33.7 19.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF998 PF06197.13 KKF95323.1 - 0.016 14.8 1.5 0.016 14.8 1.5 4.5 5 1 1 6 6 6 0 Protein of unknown function (DUF998) CD34_antigen PF06365.12 KKF95323.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF2530 PF10745.9 KKF95323.1 - 0.44 10.8 0.1 0.44 10.8 0.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) DUF4131 PF13567.6 KKF95323.1 - 7.4 6.2 11.6 2.7 7.6 0.8 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) RRM_1 PF00076.22 KKF95324.1 - 1.7e-59 197.6 0.0 2.9e-20 71.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKF95324.1 - 4.1e-10 39.4 0.0 0.0033 17.2 0.0 3.4 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KKF95324.1 - 6.4e-09 35.5 0.0 0.00018 21.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKF95324.1 - 3.4e-07 30.2 0.1 0.52 10.4 0.0 3.3 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 KKF95324.1 - 0.0011 19.2 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 2 RRM-like domain Cas_Cas2CT1978 PF09707.10 KKF95324.1 - 0.0032 17.5 0.0 0.42 10.7 0.0 2.4 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 KKF95324.1 - 0.0068 16.5 0.0 4 7.6 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 KKF95324.1 - 0.047 13.7 0.0 2.7 8.1 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain Pkinase PF00069.25 KKF95325.1 - 1.3e-50 172.2 0.1 5.2e-50 170.3 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95325.1 - 2.8e-23 82.5 0.0 6.2e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKF95325.1 - 0.00011 22.2 0.1 0.00051 20.0 0.1 2.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKF95325.1 - 0.0026 17.4 0.2 0.0082 15.8 0.2 1.8 1 1 0 1 1 1 1 RIO1 family DUF4834 PF16118.5 KKF95325.1 - 2.4 9.2 0.0 2.4 9.2 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) CTU2 PF10288.9 KKF95328.1 - 9.7e-09 35.5 0.3 8.7e-08 32.4 0.0 2.2 1 1 1 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 DUF2187 PF09953.9 KKF95328.1 - 0.045 13.7 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) Mito_carr PF00153.27 KKF95329.1 - 1.9e-59 197.6 3.8 3.5e-20 71.7 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_16 PF00722.21 KKF95330.1 - 1.7e-07 30.9 0.0 1.6e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 WD40 PF00400.32 KKF95331.1 - 4e-12 46.4 5.6 2.9e-06 27.9 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF95331.1 - 3.6e-05 24.0 0.0 1.5 9.2 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SRP9-21 PF05486.12 KKF95332.1 - 1.7e-32 111.7 3.2 2.6e-32 111.1 3.2 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) CYTH PF01928.21 KKF95332.1 - 0.054 13.4 0.0 0.084 12.8 0.0 1.3 1 1 0 1 1 1 0 CYTH domain DUF4322 PF14210.6 KKF95332.1 - 0.19 11.6 0.4 7.5 6.5 0.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4322) Ribonuc_red_sm PF00268.21 KKF95333.1 - 8.6e-122 405.9 0.6 1e-121 405.7 0.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Abhydrolase_2 PF02230.16 KKF95334.1 - 0.00034 20.5 0.0 0.0007 19.5 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KKF95334.1 - 0.0035 17.0 0.4 0.039 13.6 0.1 2.1 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 KKF95334.1 - 0.013 15.0 0.2 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DCP2 PF05026.13 KKF95335.1 - 3.3e-31 107.5 0.9 7.5e-31 106.3 0.9 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KKF95335.1 - 1.4e-17 63.9 0.1 2.7e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Lipase_3 PF01764.25 KKF95336.1 - 4.1e-07 30.0 0.0 7.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KKF95336.1 - 0.026 13.8 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 KKF95336.1 - 0.039 13.9 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Mis12 PF05859.12 KKF95337.1 - 3.2e-42 143.8 0.0 5.1e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein AIM3 PF17096.5 KKF95338.1 - 0.0015 19.4 3.3 0.0015 19.4 3.3 3.7 3 2 0 3 3 3 1 Altered inheritance of mitochondria protein 3 TCTP PF00838.17 KKF95339.1 - 6.3e-66 221.8 1.1 7e-66 221.7 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein S4 PF01479.25 KKF95339.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 S4 domain DUF2880 PF11082.8 KKF95339.1 - 0.21 11.9 1.3 30 5.0 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2880) FA_hydroxylase PF04116.13 KKF95340.1 - 2.1e-25 89.6 11.6 2.1e-25 89.6 11.6 2.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily BRI3BP PF14965.6 KKF95340.1 - 0.058 12.9 4.8 0.1 12.1 0.1 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Zip PF02535.22 KKF95340.1 - 0.14 11.3 0.9 0.21 10.8 0.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter XFP_C PF09363.10 KKF95340.1 - 0.36 10.3 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 XFP C-terminal domain DUF1764 PF08576.10 KKF95340.1 - 0.67 10.9 6.2 1.3 9.9 6.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF1682 PF07946.14 KKF95340.1 - 0.93 8.6 8.3 8.2 5.5 8.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 KKF95340.1 - 3.5 6.3 7.6 7.6 5.2 7.6 1.5 1 0 0 1 1 1 0 Presenilin TMEM51 PF15345.6 KKF95340.1 - 8.6 6.1 8.3 13 5.6 8.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3405 PF11885.8 KKF95341.1 - 1.6e-197 657.2 0.2 2e-197 656.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.24 KKF95342.1 - 5.4e-45 153.6 0.1 6.2e-45 153.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SpoU_methylase PF00588.19 KKF95342.1 - 0.061 13.5 0.0 2 8.6 0.0 2.2 1 1 0 2 2 2 0 SpoU rRNA Methylase family Arf PF00025.21 KKF95343.1 - 2e-80 268.3 0.2 2.3e-80 268.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKF95343.1 - 8.5e-15 55.0 0.0 1.2e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KKF95343.1 - 1e-14 54.4 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KKF95343.1 - 1.2e-13 50.9 0.0 1.4e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KKF95343.1 - 2e-13 50.2 1.4 1.8e-09 37.3 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KKF95343.1 - 5.9e-11 42.2 0.0 7.5e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKF95343.1 - 7.1e-07 29.3 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KKF95343.1 - 0.0081 15.5 0.9 0.028 13.7 0.9 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase PMM PF03332.13 KKF95344.1 - 1.6e-98 328.9 0.1 1.9e-98 328.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KKF95344.1 - 0.00011 22.0 0.0 0.0069 16.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KKF95344.1 - 0.029 13.9 0.0 0.99 8.9 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Cnd2 PF05786.14 KKF95346.1 - 7.3e-303 1007.1 18.1 8.2e-303 1006.9 18.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KKF95346.1 - 0.0084 16.3 0.1 0.027 14.7 0.1 1.9 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Vps51 PF08700.11 KKF95347.1 - 0.019 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Vps51/Vps67 DUF5327 PF17261.2 KKF95347.1 - 0.19 12.5 6.0 0.27 12.0 6.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Ax_dynein_light PF10211.9 KKF95347.1 - 1.2 9.1 8.6 1.4 8.8 8.6 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain HAMP PF00672.25 KKF95348.1 - 9.9e-41 137.9 15.0 1.3e-07 31.9 0.6 7.5 6 1 0 6 6 6 6 HAMP domain HATPase_c PF02518.26 KKF95348.1 - 3.8e-31 107.9 0.4 1.5e-30 105.9 0.4 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKF95348.1 - 8.2e-27 93.6 3.6 3.9e-26 91.4 0.7 2.9 3 0 0 3 3 2 1 Response regulator receiver domain HisKA PF00512.25 KKF95348.1 - 1.2e-17 63.7 4.1 3.2e-17 62.3 0.7 3.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Fib_alpha PF08702.10 KKF95348.1 - 6.6e-05 23.1 27.2 0.073 13.3 0.4 6.2 6 0 0 6 6 6 3 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 KKF95348.1 - 0.00011 22.4 19.2 4.3 7.8 0.0 7.7 4 2 3 7 7 6 1 Syntaxin-like protein DUF3829 PF12889.7 KKF95348.1 - 0.00077 19.0 8.3 0.58 9.6 0.1 4.3 3 2 1 4 4 4 2 Protein of unknown function (DUF3829) Gp-FAR-1 PF05823.12 KKF95348.1 - 0.0024 18.2 1.4 24 5.2 0.0 5.1 2 1 1 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4279 PF14106.6 KKF95348.1 - 0.0095 16.1 0.0 32 4.8 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4279) HTH_6 PF01418.17 KKF95348.1 - 0.021 14.8 0.0 2.5 8.2 0.0 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family DUF948 PF06103.11 KKF95348.1 - 0.022 15.0 45.6 1.7 9.0 2.6 9.5 2 1 3 6 6 6 0 Bacterial protein of unknown function (DUF948) GLE1 PF07817.13 KKF95348.1 - 0.073 12.3 7.3 8.5 5.5 0.2 4.6 2 1 2 4 4 4 0 GLE1-like protein Spectrin PF00435.21 KKF95348.1 - 0.073 13.6 9.9 3 8.4 0.0 5.6 5 1 2 7 7 6 0 Spectrin repeat ApoA-II PF04711.13 KKF95348.1 - 0.078 13.1 0.1 0.79 9.9 0.0 2.9 2 1 0 2 2 1 0 Apolipoprotein A-II (ApoA-II) DUF883 PF05957.13 KKF95348.1 - 0.18 12.5 15.1 8.1 7.1 0.3 6.0 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF883) DUF1759 PF03564.15 KKF95348.1 - 0.26 11.2 3.9 68 3.4 0.1 4.5 6 0 0 6 6 4 0 Protein of unknown function (DUF1759) PilJ PF13675.6 KKF95348.1 - 0.27 11.3 12.8 4 7.5 0.1 6.2 2 1 6 8 8 8 0 Type IV pili methyl-accepting chemotaxis transducer N-term MCM_N PF14551.6 KKF95348.1 - 0.41 11.2 3.2 22 5.7 0.0 4.2 5 0 0 5 5 4 0 MCM N-terminal domain DUF4795 PF16043.5 KKF95348.1 - 0.49 10.0 22.9 0.45 10.1 0.2 5.2 1 1 2 4 4 4 0 Domain of unknown function (DUF4795) Peptidase_C23 PF05379.11 KKF95348.1 - 0.71 10.0 2.9 4.3 7.5 0.1 3.4 3 0 0 3 3 3 0 Carlavirus endopeptidase CENP-F_leu_zip PF10473.9 KKF95348.1 - 2.7 8.0 24.8 6.6 6.8 0.1 7.9 7 1 2 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PITH PF06201.13 KKF95349.1 - 2.6e-32 112.1 0.0 3.8e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KKF95349.1 - 7.6e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DNA_pol_phi PF04931.13 KKF95350.1 - 9e-167 556.5 29.7 1.8e-166 555.5 29.7 1.4 1 1 0 1 1 1 1 DNA polymerase phi Proteasome PF00227.26 KKF95351.1 - 1.9e-46 157.9 0.0 9.1e-32 110.1 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KKF95351.1 - 5.8e-11 41.9 0.1 5.8e-11 41.9 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature NOA36 PF06524.12 KKF95351.1 - 0.82 8.9 12.3 1.1 8.5 12.3 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 KKF95351.1 - 1.9 7.6 12.7 2.3 7.2 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Caldesmon PF02029.15 KKF95352.1 - 0.056 12.2 12.7 0.078 11.7 12.7 1.1 1 0 0 1 1 1 0 Caldesmon LMBR1 PF04791.16 KKF95352.1 - 0.24 10.3 1.5 0.29 10.0 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DnaJ PF00226.31 KKF95353.1 - 1.8e-09 37.6 0.3 6.2e-09 35.8 0.3 2.0 1 1 0 1 1 1 1 DnaJ domain CwfJ_C_2 PF04676.14 KKF95354.1 - 1.6e-15 57.8 0.1 3.5e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KKF95354.1 - 4.1e-09 36.4 0.0 1.5e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 DRIM PF07539.12 KKF95355.1 - 1.6e-177 591.6 1.6 5.2e-177 589.9 0.8 2.3 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.22 KKF95355.1 - 0.0018 18.4 5.0 4.5 7.8 0.1 7.0 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 KKF95355.1 - 0.0022 18.3 1.9 42 4.6 0.0 5.9 5 0 0 5 5 5 0 HEAT repeats CLASP_N PF12348.8 KKF95355.1 - 0.042 13.4 0.2 4.2 6.9 0.0 3.3 3 0 0 3 3 3 0 CLASP N terminal Xpo1 PF08389.12 KKF95355.1 - 0.16 12.1 2.6 32 4.5 0.1 5.0 5 0 0 5 5 5 0 Exportin 1-like protein Trypan_PARP PF05887.11 KKF95355.1 - 0.41 10.6 7.6 0.078 13.0 3.2 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cullin PF00888.22 KKF95356.1 - 3.8e-167 557.6 0.3 4.6e-167 557.3 0.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KKF95356.1 - 9.2e-25 86.5 2.3 3e-24 84.8 1.0 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF5611 PF18446.1 KKF95356.1 - 5 8.1 6.6 3 8.7 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF5611) MPC PF03650.13 KKF95357.1 - 7e-36 122.7 0.0 8.7e-36 122.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Thioredoxin PF00085.20 KKF95358.1 - 5.7e-23 80.9 0.1 6.2e-23 80.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KKF95358.1 - 3.1e-06 27.6 0.2 3.6e-05 24.2 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KKF95358.1 - 0.00012 22.4 0.0 0.00032 21.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KKF95358.1 - 0.00018 21.3 0.0 0.00023 20.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KKF95358.1 - 0.00037 20.4 0.1 0.00064 19.6 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKF95358.1 - 0.0013 18.5 0.2 0.0058 16.4 0.2 1.8 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 KKF95358.1 - 0.0058 16.8 0.0 0.0085 16.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KKF95358.1 - 0.017 14.5 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KKF95358.1 - 0.079 13.0 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain DSBA PF01323.20 KKF95358.1 - 0.094 12.5 0.4 11 5.7 0.0 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TraF PF13728.6 KKF95358.1 - 0.16 11.8 0.1 0.29 10.9 0.1 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein UQ_con PF00179.26 KKF95359.1 - 8.1e-52 174.6 0.0 9.2e-52 174.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKF95359.1 - 0.00032 20.4 0.0 0.00036 20.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KKF95359.1 - 0.064 13.5 0.0 0.083 13.2 0.0 1.4 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.23 KKF95360.1 - 4.4e-89 298.3 1.6 6.8e-89 297.7 1.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKF95360.1 - 2e-37 127.5 0.8 5.2e-37 126.2 0.8 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKF95360.1 - 2.1e-05 24.3 0.2 5.2e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KKF95360.1 - 0.068 13.0 5.2 3.1 7.7 0.1 3.4 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SE PF08491.10 KKF95361.1 - 3.8e-90 301.7 0.0 5.2e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KKF95361.1 - 5.4e-09 35.8 0.0 4.9e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKF95361.1 - 4.2e-06 26.6 0.0 0.00012 21.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KKF95361.1 - 0.00088 18.7 0.2 0.0013 18.1 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKF95361.1 - 0.0011 19.1 0.1 0.0025 18.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 KKF95361.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KKF95361.1 - 0.0022 17.9 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KKF95361.1 - 0.0031 16.8 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KKF95361.1 - 0.0064 15.6 0.1 0.015 14.4 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KKF95361.1 - 0.0066 15.7 0.2 0.016 14.5 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKF95361.1 - 0.008 15.3 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KKF95361.1 - 0.076 11.7 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 KKF95361.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KKF95361.1 - 0.17 11.1 0.1 0.31 10.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glycos_transf_2 PF00535.26 KKF95362.1 - 4.7e-27 94.8 0.0 7.4e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KKF95362.1 - 2.2e-11 44.1 0.1 3.1e-10 40.3 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KKF95362.1 - 0.0036 16.8 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 SMK-1 PF04802.15 KKF95363.1 - 2.4e-77 259.1 6.3 6.1e-77 257.8 6.3 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 RTP1_C2 PF10304.9 KKF95363.1 - 0.15 11.8 0.4 27 4.6 0.0 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 2 Cyt-b5 PF00173.28 KKF95364.1 - 3.4e-20 71.9 1.3 8.5e-20 70.7 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KKF95364.1 - 6.3e-11 42.7 10.1 6.3e-11 42.7 10.1 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KKF95364.1 - 0.0052 17.0 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region zf-H2C2_2 PF13465.6 KKF95365.1 - 2.1e-13 50.0 7.5 1.6e-07 31.4 0.4 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KKF95365.1 - 2.5e-12 46.5 14.2 2.2e-06 27.8 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KKF95365.1 - 1.3e-08 34.6 6.7 0.00019 21.3 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KKF95365.1 - 1.8e-08 34.5 13.3 0.00024 21.7 1.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKF95365.1 - 1.8e-06 28.0 6.7 0.053 13.8 0.1 4.1 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKF95365.1 - 0.0013 19.1 9.8 0.008 16.5 0.2 3.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KKF95365.1 - 0.02 15.2 1.8 0.037 14.3 1.8 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 KKF95365.1 - 0.34 11.2 4.3 11 6.3 0.1 2.4 1 1 0 2 2 2 0 LIM domain zf-C2HE PF16278.5 KKF95365.1 - 0.92 10.0 4.9 5.1 7.6 0.3 2.7 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger C5HCH PF17982.1 KKF95365.1 - 1.8 8.8 7.0 11 6.3 1.0 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-LYAR PF08790.11 KKF95365.1 - 6.1 6.9 5.0 39 4.3 0.5 3.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger AOX PF01786.17 KKF95366.1 - 1e-79 267.1 0.2 1.2e-79 266.8 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase AA_permease PF00324.21 KKF95367.1 - 5.2e-133 444.1 38.0 2.8e-131 438.4 31.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKF95367.1 - 1.4e-34 119.7 35.6 1.8e-34 119.4 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KKF95367.1 - 0.01 14.7 1.0 0.01 14.7 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) Mago-bind PF09282.10 KKF95368.1 - 8.2e-13 48.0 4.6 2e-12 46.7 4.6 1.7 1 0 0 1 1 1 1 Mago binding RWD PF05773.22 KKF95369.1 - 2.7e-15 56.7 0.1 5.8e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 KKF95369.1 - 0.00033 21.1 12.3 0.00033 21.1 12.3 2.2 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 HTH_Tnp_1 PF01527.20 KKF95369.1 - 0.1 12.9 6.7 0.41 11.0 0.6 2.5 2 0 0 2 2 2 0 Transposase XRN_M PF17846.1 KKF95369.1 - 0.36 9.7 3.5 0.43 9.5 3.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain TPR_12 PF13424.6 KKF95370.1 - 1.5e-13 50.8 3.1 3.3e-08 33.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKF95370.1 - 1.1e-11 43.9 0.3 0.0001 22.1 0.0 5.0 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKF95370.1 - 1.4e-10 40.5 0.0 0.00014 21.8 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKF95370.1 - 9.3e-10 38.9 8.3 0.00024 21.5 0.1 4.8 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KKF95370.1 - 8.1e-09 34.9 0.0 0.00058 19.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKF95370.1 - 1.4e-08 34.9 12.6 0.076 13.9 0.0 6.3 5 2 1 7 7 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKF95370.1 - 5.4e-06 26.1 0.3 0.029 14.4 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKF95370.1 - 1.3e-05 25.8 6.6 0.067 13.9 0.0 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KKF95370.1 - 7.5e-05 22.2 4.4 0.016 14.6 0.0 3.2 2 1 1 3 3 3 2 MalT-like TPR region ANAPC3 PF12895.7 KKF95370.1 - 7.9e-05 22.8 0.2 1.6 9.0 0.1 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KKF95370.1 - 0.014 16.0 3.8 2.6 8.9 0.0 5.1 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KKF95370.1 - 0.018 15.4 0.1 33 5.2 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat ERAP1_C PF11838.8 KKF95370.1 - 0.05 13.2 2.1 0.12 11.9 0.0 2.3 3 0 0 3 3 3 0 ERAP1-like C-terminal domain TPR_10 PF13374.6 KKF95370.1 - 0.082 12.8 7.0 5.9 6.9 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KKF95370.1 - 0.1 12.0 0.3 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 Coatomer epsilon subunit PriC PF07445.12 KKF95370.1 - 0.38 10.6 2.6 0.39 10.6 0.4 2.1 2 0 0 2 2 2 0 Primosomal replication protein priC TPR_4 PF07721.14 KKF95370.1 - 0.74 10.6 8.3 24 5.9 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKF95370.1 - 2.6 7.8 4.6 49 3.7 0.0 3.9 5 0 0 5 5 5 0 TPR repeat TPR_21 PF09976.9 KKF95370.1 - 2.8 7.6 8.1 0.3 10.7 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain Lum_binding PF00677.17 KKF95371.1 - 3.2e-44 148.8 1.2 1.4e-21 76.3 0.2 2.0 2 0 0 2 2 2 2 Lumazine binding domain Ribosomal_L21p PF00829.21 KKF95371.1 - 0.077 13.3 0.0 0.42 10.9 0.0 2.1 1 1 1 2 2 2 0 Ribosomal prokaryotic L21 protein ERCC4 PF02732.15 KKF95372.1 - 1.8e-24 86.7 0.1 3e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 ERCC4 domain SAND PF01342.21 KKF95372.1 - 0.14 11.9 0.1 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 SAND domain PGM_PMM_I PF02878.16 KKF95373.1 - 5.3e-13 48.9 0.2 4.7e-07 29.6 0.0 3.1 2 1 2 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KKF95373.1 - 1.5e-09 37.8 0.5 5.2e-09 36.1 0.3 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KKF95373.1 - 0.0049 17.5 0.1 1.7 9.3 0.0 3.0 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KKF95373.1 - 0.0052 17.0 0.1 0.014 15.6 0.1 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Methyltransf_25 PF13649.6 KKF95374.1 - 1.4e-11 45.0 0.0 4.4e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF95374.1 - 2.8e-10 40.2 0.1 1.3e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KKF95374.1 - 5.3e-10 39.2 0.0 8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KKF95374.1 - 1.5e-08 35.2 0.0 5.9e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKF95374.1 - 2.1e-05 23.6 0.1 3e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 KKF95374.1 - 2.6e-05 24.1 0.0 6.5e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KKF95374.1 - 9.9e-05 22.3 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF95374.1 - 0.00082 20.1 0.0 0.002 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKF95374.1 - 0.0027 17.3 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KKF95374.1 - 0.0052 16.1 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 KKF95374.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 KKF95374.1 - 0.031 14.3 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRMT5_C PF17286.2 KKF95374.1 - 0.039 13.8 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Sugar_tr PF00083.24 KKF95375.1 - 2.2e-28 99.3 22.4 1.5e-17 63.6 5.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Metallophos PF00149.28 KKF95376.1 - 2.2e-09 38.1 0.2 4.7e-09 37.0 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF993 PF06187.11 KKF95376.1 - 0.13 11.1 0.0 0.28 10.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF993) MFS_1 PF07690.16 KKF95377.1 - 1.4e-38 132.7 67.1 1.4e-29 103.1 27.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKF95377.1 - 2.2e-16 59.4 18.8 2.2e-16 59.4 18.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKF95377.1 - 2.4e-14 53.0 10.2 2.4e-14 53.0 10.2 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter ANAPC_CDC26 PF10471.9 KKF95378.1 - 2.5e-10 41.0 21.8 2.9e-08 34.4 18.7 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 BRF1 PF07741.13 KKF95378.1 - 1.6 9.1 5.8 1.1 9.6 4.0 1.5 1 1 1 2 2 2 0 Brf1-like TBP-binding domain Fasciclin PF02469.22 KKF95379.1 - 0.00031 20.9 0.0 0.00051 20.2 0.0 1.3 1 1 0 1 1 1 1 Fasciclin domain D-ser_dehydrat PF14031.6 KKF95380.1 - 1.7e-22 79.9 0.0 6.7e-22 78.0 0.0 2.0 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KKF95380.1 - 4.1e-11 43.0 0.0 6.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain FAD_binding_2 PF00890.24 KKF95381.1 - 5.4e-85 286.0 0.1 6.8e-85 285.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KKF95381.1 - 7.7e-22 77.2 0.0 4.1e-20 71.7 0.0 2.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KKF95381.1 - 2.1e-14 53.9 0.1 3.9e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KKF95381.1 - 5.7e-09 35.8 0.4 2.2e-08 33.9 0.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKF95381.1 - 2.8e-07 30.7 1.3 3.2e-06 27.3 0.2 2.9 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKF95381.1 - 1e-06 27.7 0.7 0.0061 15.3 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 KKF95381.1 - 1.1e-06 28.1 0.2 1.5e-05 24.4 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKF95381.1 - 1e-05 25.0 0.0 0.096 11.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKF95381.1 - 9.9e-05 21.7 0.5 0.02 14.1 0.1 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KKF95381.1 - 0.0011 18.1 1.4 0.2 10.7 0.9 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KKF95381.1 - 0.0017 17.7 0.4 0.3 10.3 0.1 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KKF95381.1 - 0.012 16.1 0.6 2.1 8.9 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKF95381.1 - 0.014 14.7 2.1 0.03 13.6 2.1 1.6 1 1 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KKF95381.1 - 0.087 12.1 0.4 0.16 11.3 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HTH_AraC PF00165.23 KKF95381.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family BRK PF07533.16 KKF95381.1 - 0.15 11.7 0.0 0.44 10.2 0.0 1.9 1 0 0 1 1 1 0 BRK domain Sugar_tr PF00083.24 KKF95382.1 - 1e-126 423.5 21.5 1.2e-126 423.3 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF95382.1 - 3.1e-22 79.0 36.8 1.3e-16 60.5 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 KKF95382.1 - 0.011 15.6 1.1 0.011 15.6 1.1 2.8 3 0 0 3 3 3 0 Glycine zipper 2TM domain CAP_N PF01213.19 KKF95385.1 - 0.65 9.4 3.7 0.82 9.1 3.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Arf PF00025.21 KKF95386.1 - 2e-38 131.6 0.0 3.1e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KKF95386.1 - 2.3e-11 43.5 0.0 3.4e-06 26.4 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KKF95386.1 - 2.3e-08 34.3 0.0 6e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKF95386.1 - 1.5e-07 31.2 0.0 0.0022 17.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Gtr1_RagA PF04670.12 KKF95386.1 - 5.6e-07 29.2 0.0 6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKF95386.1 - 2.1e-06 27.3 0.0 5.6e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KKF95386.1 - 0.00028 20.5 0.0 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKF95386.1 - 0.0011 19.1 0.0 0.0029 17.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNase_PH PF01138.21 KKF95387.1 - 1e-24 87.5 0.0 1.5e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKF95387.1 - 5.6e-10 39.1 0.1 1.4e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 KKF95388.1 - 2.6e-84 282.9 14.9 3e-84 282.6 14.9 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3381 PF11861.8 KKF95388.1 - 0.02 14.7 9.9 0.03 14.1 9.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) SDA1 PF05285.12 KKF95388.1 - 0.49 9.8 24.6 0.61 9.5 24.6 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KKF95388.1 - 1.2 8.4 23.6 1.6 8.0 23.6 1.3 1 0 0 1 1 1 0 BUD22 Casc1_N PF15927.5 KKF95388.1 - 1.2 8.7 11.4 2 8.1 10.9 1.5 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Nop14 PF04147.12 KKF95388.1 - 1.8 6.7 25.0 2 6.5 25.0 1.1 1 0 0 1 1 1 0 Nop14-like family NAM-associated PF14303.6 KKF95388.1 - 4.6 7.9 17.2 11 6.7 17.2 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Presenilin PF01080.17 KKF95388.1 - 7.6 5.2 5.9 9.1 4.9 5.9 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 KKF95388.1 - 9.7 4.8 10.8 11 4.6 10.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FGGY_C PF02782.16 KKF95389.1 - 6.9e-24 84.7 0.0 1.1e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKF95389.1 - 1.6e-05 24.6 0.1 3.3e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.21 KKF95390.1 - 3.4e-32 111.8 4.4 4.4e-32 111.4 4.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KKF95390.1 - 0.0027 17.8 0.1 0.0061 16.7 0.0 1.6 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter UreE_C PF05194.12 KKF95390.1 - 4.8 7.7 9.9 23 5.6 0.1 2.5 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain Catalase PF00199.19 KKF95391.1 - 6.3e-193 641.1 0.6 8.6e-193 640.6 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KKF95391.1 - 2.2e-12 47.0 0.2 7e-12 45.4 0.2 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive FMN_bind_2 PF04299.12 KKF95391.1 - 0.19 11.4 4.1 0.067 12.9 1.2 1.7 2 0 0 2 2 2 0 Putative FMN-binding domain Arf PF00025.21 KKF95392.1 - 1.4e-19 70.2 0.0 1.6e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Milton PF12448.8 KKF95392.1 - 0.063 13.4 0.0 0.072 13.2 0.0 1.1 1 0 0 1 1 1 0 Kinesin associated protein Skp1 PF01466.19 KKF95393.1 - 9e-29 99.3 0.2 1.9e-28 98.3 0.2 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KKF95393.1 - 2e-20 72.7 0.7 4.7e-20 71.5 0.4 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Ribosomal_L1 PF00687.21 KKF95394.1 - 1.7e-45 155.3 0.3 1.9e-45 155.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF2428 PF10350.9 KKF95395.1 - 1.2e-55 188.7 0.0 2.4e-55 187.7 0.0 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.6 KKF95395.1 - 3.5e-05 24.1 1.3 0.00057 20.2 0.2 3.6 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KKF95395.1 - 0.0007 20.0 0.9 0.0035 17.8 0.1 2.8 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KKF95395.1 - 0.0029 17.7 5.5 2.9 8.4 0.1 5.8 5 0 0 5 5 5 1 HEAT repeat Sec7_N PF12783.7 KKF95395.1 - 0.033 14.1 0.1 0.14 12.0 0.1 2.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Cnd1 PF12717.7 KKF95395.1 - 0.11 12.6 0.0 0.39 10.7 0.0 2.0 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Autophagy_act_C PF03987.15 KKF95395.1 - 0.15 12.7 0.0 0.43 11.2 0.0 1.9 1 0 0 1 1 1 0 Autophagocytosis associated protein, active-site domain DUF3074 PF11274.8 KKF95396.1 - 3.9e-44 150.8 0.0 3.9e-44 150.8 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3074) VASt PF16016.5 KKF95397.1 - 2.7e-30 105.8 0.1 6.2e-30 104.6 0.1 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KKF95397.1 - 3.1e-16 59.8 0.1 5.6e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KKF95397.1 - 1.7e-06 28.5 1.4 3.1e-06 27.6 0.1 2.2 2 0 0 2 2 2 1 PH domain BAR PF03114.18 KKF95397.1 - 0.012 15.3 0.6 0.024 14.3 0.6 1.4 1 0 0 1 1 1 0 BAR domain Abhydrolase_6 PF12697.7 KKF95398.1 - 8e-12 46.2 0.0 4.6e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKF95398.1 - 1.9e-05 24.1 0.1 0.0043 16.4 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKF95398.1 - 0.0076 15.9 0.0 0.014 15.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.8 KKF95398.1 - 0.026 14.1 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF1057 PF06342.12 KKF95398.1 - 0.084 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 KKF95398.1 - 0.17 11.7 0.3 4.6 7.0 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase GMC_oxred_N PF00732.19 KKF95401.1 - 5.1e-22 78.6 1.1 1.3e-21 77.2 0.1 1.8 1 1 1 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KKF95401.1 - 3.7e-06 26.4 0.1 5.9e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKF95401.1 - 1.3e-05 25.3 0.2 3.3e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KKF95401.1 - 1.5e-05 24.4 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KKF95401.1 - 0.00016 20.9 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KKF95401.1 - 0.0068 15.1 0.1 0.0099 14.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KKF95401.1 - 0.012 14.9 0.1 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KKF95401.1 - 0.021 15.4 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKF95401.1 - 0.065 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 KKF95401.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KKF95401.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KKF95401.1 - 0.2 12.2 0.0 0.45 11.0 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 KKF95401.1 - 0.27 10.8 1.7 0.51 9.9 1.7 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ELO PF01151.18 KKF95402.1 - 3.9e-77 259.2 10.6 5.3e-77 258.7 10.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DGF-1_4 PF11024.8 KKF95402.1 - 0.67 10.8 3.5 0.62 10.9 0.5 2.2 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 DUF3082 PF11282.8 KKF95402.1 - 7.5 6.9 8.3 0.57 10.5 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) S-methyl_trans PF02574.16 KKF95403.1 - 5.5e-49 167.4 0.0 6.3e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Fungal_trans_2 PF11951.8 KKF95404.1 - 1e-09 37.7 0.1 1.5e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF95404.1 - 1.1e-08 35.0 9.8 1.8e-08 34.4 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KKF95405.1 - 1.3e-11 43.9 0.0 1.5e-11 43.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SPRY PF00622.28 KKF95406.1 - 2.9e-19 69.3 0.0 5.2e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain RhoGEF PF00621.20 KKF95410.1 - 0.11 12.8 0.0 0.34 11.1 0.0 1.8 1 1 0 1 1 1 0 RhoGEF domain DUF1749 PF08538.10 KKF95411.1 - 7e-66 222.3 0.0 8.3e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KKF95411.1 - 4.9e-08 33.8 0.0 1.1e-07 32.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKF95411.1 - 1e-05 25.3 0.0 0.00014 21.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKF95411.1 - 0.00018 20.9 0.0 0.0031 16.8 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KKF95411.1 - 0.028 14.3 0.0 0.09 12.6 0.0 1.8 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_9 PF10081.9 KKF95411.1 - 0.03 13.4 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family LCAT PF02450.15 KKF95411.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 KKF95412.1 - 1.6e-64 217.9 0.0 1.8e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KKF95412.1 - 1.9e-07 31.9 0.0 2.3e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKF95412.1 - 0.00018 20.9 0.0 0.0046 16.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKF95412.1 - 0.0041 16.8 0.0 0.029 14.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KKF95412.1 - 0.019 14.8 0.0 0.052 13.4 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase Peptidase_S9 PF00326.21 KKF95412.1 - 0.03 13.8 0.0 1.1 8.6 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family VirJ PF06057.11 KKF95412.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF3455 PF11937.8 KKF95413.1 - 1.3e-36 126.3 0.0 1.8e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KKF95413.1 - 0.094 12.9 0.5 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) CASP_C PF08172.12 KKF95414.1 - 4.4e-91 304.7 0.0 4.4e-91 304.7 0.0 3.5 4 0 0 4 4 4 1 CASP C terminal APG6_N PF17675.1 KKF95414.1 - 0.0035 17.9 48.3 2 9.0 12.2 5.6 2 1 2 5 5 5 1 Apg6 coiled-coil region Cortex-I_coil PF09304.10 KKF95414.1 - 0.0056 16.9 3.9 0.0056 16.9 3.9 5.4 5 2 1 6 6 5 1 Cortexillin I, coiled coil TolA_bind_tri PF16331.5 KKF95414.1 - 0.0078 16.3 28.7 0.46 10.6 0.4 5.6 6 0 0 6 6 6 3 TolA binding protein trimerisation bZIP_2 PF07716.15 KKF95414.1 - 0.022 14.8 2.1 0.022 14.8 2.1 8.0 8 1 1 9 9 9 0 Basic region leucine zipper DivIC PF04977.15 KKF95414.1 - 0.042 13.6 0.3 0.042 13.6 0.3 7.3 7 2 1 8 8 8 0 Septum formation initiator ZapB PF06005.12 KKF95414.1 - 0.05 14.0 42.8 0.11 12.9 0.0 6.4 5 1 1 6 6 6 0 Cell division protein ZapB CENP-H PF05837.12 KKF95414.1 - 0.077 13.4 0.3 0.077 13.4 0.3 5.8 4 1 2 6 6 6 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 KKF95414.1 - 0.18 11.1 32.0 0.16 11.3 5.0 4.5 2 1 1 4 4 4 0 Domain of unknown function (DUF4407) YabA PF06156.13 KKF95414.1 - 0.35 11.5 29.9 4.2 8.1 0.1 6.0 4 1 1 6 6 6 0 Initiation control protein YabA CALCOCO1 PF07888.11 KKF95414.1 - 0.48 9.2 43.8 0.076 11.9 1.0 4.8 3 1 0 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like MscS_porin PF12795.7 KKF95414.1 - 0.57 9.7 47.8 0.4 10.2 1.4 4.7 4 2 0 4 4 4 0 Mechanosensitive ion channel porin domain SKA1 PF07160.12 KKF95414.1 - 0.96 9.2 20.8 2.2 8.1 7.3 4.4 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 1 Rab5-bind PF09311.11 KKF95414.1 - 2 7.7 33.7 0.48 9.8 0.5 5.1 3 1 1 5 5 5 0 Rabaptin-like protein GAS PF13851.6 KKF95414.1 - 2 7.7 46.9 0.63 9.3 1.4 5.7 5 1 0 5 5 5 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KKF95414.1 - 2 8.8 41.3 3.5 8.0 1.1 4.5 3 1 3 6 6 6 0 Fez1 TPR_MLP1_2 PF07926.12 KKF95414.1 - 2.3 8.3 58.3 0.39 10.8 6.4 7.1 5 1 1 6 6 6 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 KKF95414.1 - 4.2 6.8 41.1 0.98 8.9 9.3 4.6 2 1 2 4 4 3 0 Intermediate filament protein DUF3584 PF12128.8 KKF95414.1 - 5.7 4.3 41.3 0.64 7.5 22.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) Vps39_2 PF10367.9 KKF95415.1 - 2.7e-08 34.2 0.0 1e-07 32.4 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KKF95415.1 - 0.00089 19.5 0.1 0.017 15.4 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 zf-C2H2 PF00096.26 KKF95416.1 - 0.0003 21.1 22.8 0.68 10.5 0.4 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-met PF12874.7 KKF95416.1 - 0.012 16.0 1.5 7.7 7.1 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKF95416.1 - 0.015 15.6 5.5 20 5.6 0.1 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding TOC159_MAD PF11886.8 KKF95416.1 - 0.032 13.1 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain zf-C2H2_4 PF13894.6 KKF95416.1 - 0.27 12.2 24.3 0.28 12.1 0.8 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2HE PF16278.5 KKF95416.1 - 1.1 9.8 6.4 0.66 10.5 2.5 2.5 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger CMD PF02627.20 KKF95417.1 - 1.6e-05 24.9 0.0 0.00058 19.9 0.0 2.4 3 0 0 3 3 3 2 Carboxymuconolactone decarboxylase family DUF1514 PF07438.11 KKF95418.1 - 0.034 14.0 0.1 0.12 12.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) NrsF PF06532.11 KKF95418.1 - 0.63 9.7 6.4 3.3 7.4 1.2 2.2 2 0 0 2 2 2 0 Negative regulator of sigma F Sacchrp_dh_C PF16653.5 KKF95419.1 - 1.2e-92 310.8 0.0 2.6e-92 309.7 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KKF95419.1 - 1.7e-25 89.8 0.3 2.8e-25 89.1 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KKF95419.1 - 2.3e-05 24.4 1.0 3e-05 24.0 0.3 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 KKF95419.1 - 8.8e-05 22.6 0.0 0.00016 21.7 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KKF95419.1 - 0.00023 20.8 0.2 0.0061 16.1 0.0 2.8 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 KKF95419.1 - 0.0012 19.7 0.1 0.0027 18.5 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KKF95419.1 - 0.037 14.7 0.2 0.069 13.8 0.2 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Epimerase PF01370.21 KKF95419.1 - 0.048 13.1 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_transf_8 PF01501.20 KKF95420.1 - 5.3e-22 78.6 0.4 5e-21 75.4 0.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KKF95420.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 KKF95420.1 - 0.034 14.1 0.1 0.07 13.1 0.1 1.5 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Cyt_bd_oxida_II PF02322.15 KKF95421.1 - 0.008 15.6 2.5 0.012 15.0 2.5 1.2 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II Virul_fac_BrkB PF03631.15 KKF95421.1 - 0.011 15.4 4.7 0.015 14.9 4.7 1.1 1 0 0 1 1 1 0 Virulence factor BrkB RCDG1 PF15725.5 KKF95421.1 - 0.015 15.7 0.4 0.031 14.7 0.4 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein DuoxA PF10204.9 KKF95421.1 - 0.027 13.5 2.9 0.045 12.8 2.9 1.4 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF2207 PF09972.9 KKF95421.1 - 0.066 12.0 0.9 0.084 11.6 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF681 PF05080.12 KKF95421.1 - 0.086 13.5 0.1 0.21 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF681) WTF PF03303.13 KKF95421.1 - 0.43 10.3 4.0 0.65 9.7 4.0 1.3 1 0 0 1 1 1 0 WTF protein 2TM PF13239.6 KKF95421.1 - 6.5 7.1 7.5 0.91 9.9 2.9 2.0 2 1 0 2 2 2 0 2TM domain Aldo_ket_red PF00248.21 KKF95422.1 - 3.5e-22 79.0 0.0 1.3e-11 44.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Abhydrolase_2 PF02230.16 KKF95423.1 - 6.9e-18 65.3 0.0 9e-11 42.0 0.1 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KKF95423.1 - 0.036 13.3 0.0 3.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peroxidase_2 PF01328.17 KKF95424.1 - 2e-36 126.3 0.0 2.9e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Gly_transf_sug PF04488.15 KKF95425.1 - 1e-12 48.5 0.1 2.1e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Fip1 PF05182.13 KKF95426.1 - 5.7e-20 70.5 1.3 1.1e-19 69.7 1.3 1.4 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.6 KKF95427.1 - 0.06 14.2 5.7 0.06 14.2 5.7 1.5 2 0 0 2 2 2 0 Nucleoporin FG repeat region RNA_pol_3_Rpc31 PF11705.8 KKF95428.1 - 1.2e-54 186.0 8.2 1.5e-54 185.7 8.2 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 KKF95428.1 - 9.1 5.5 11.8 14 4.9 11.8 1.3 1 0 0 1 1 1 0 BUD22 Sec7 PF01369.20 KKF95430.1 - 1.2e-71 240.2 1.9 1.2e-71 240.2 1.9 2.0 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 KKF95430.1 - 4.2e-33 113.1 13.2 5.7e-33 112.6 0.1 5.9 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 KKF95430.1 - 8.4e-33 113.5 1.9 8.4e-33 113.5 1.9 4.1 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KKF95430.1 - 4.2e-22 78.7 2.0 1.4e-20 73.7 0.1 3.4 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 NPV_P10 PF05531.12 KKF95431.1 - 0.00042 20.7 3.0 0.033 14.7 0.1 3.4 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein Pedibin PF08182.11 KKF95431.1 - 1.1 9.1 6.3 29 4.6 6.4 2.9 1 1 1 2 2 2 0 Pedibin/Hym-346 family DUF4407 PF14362.6 KKF95431.1 - 1.9 7.8 37.9 0.12 11.7 17.7 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 KKF95431.1 - 3.5 7.8 9.7 7.1 6.8 0.9 3.4 3 0 0 3 3 3 0 TolA binding protein trimerisation GMC_oxred_N PF00732.19 KKF95432.1 - 3.6e-72 243.2 0.0 1e-71 241.8 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Sulfotransfer_4 PF17784.1 KKF95432.1 - 8e-51 172.9 0.0 1.8e-50 171.7 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase domain GMC_oxred_C PF05199.13 KKF95432.1 - 1.8e-25 90.1 0.0 3.7e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KKF95432.1 - 0.00018 20.8 0.1 0.00044 19.6 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KKF95432.1 - 0.0014 18.8 0.0 0.0054 16.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Sulfotransfer_3 PF13469.6 KKF95432.1 - 0.0016 18.8 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family DAO PF01266.24 KKF95432.1 - 0.0056 16.3 0.1 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKF95432.1 - 0.0085 15.2 0.2 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KKF95432.1 - 0.0085 15.2 0.0 0.92 8.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain AA_permease_2 PF13520.6 KKF95433.1 - 5.5e-89 298.9 37.6 7.2e-89 298.5 37.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKF95433.1 - 6.1e-18 64.7 34.8 8.8e-18 64.1 34.8 1.2 1 0 0 1 1 1 1 Amino acid permease Sigma_reg_N PF13800.6 KKF95433.1 - 0.19 12.0 3.3 4.5 7.6 0.0 3.5 3 1 0 3 3 3 0 Sigma factor regulator N-terminal GH131_N PF18271.1 KKF95434.1 - 3.7e-83 279.1 0.3 4.2e-83 279.0 0.3 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Zip PF02535.22 KKF95435.1 - 1.4e-39 136.3 28.7 9.5e-17 61.2 2.4 3.4 2 1 1 3 3 3 3 ZIP Zinc transporter Thyroglobulin_1 PF00086.18 KKF95435.1 - 0.17 11.6 1.0 0.76 9.5 0.1 2.2 2 0 0 2 2 2 0 Thyroglobulin type-1 repeat WW_FCH_linker PF16623.5 KKF95435.1 - 0.39 11.5 0.1 0.39 11.5 0.1 2.5 2 1 1 3 3 3 0 Unstructured linker region between on GAS7 protein ADH_N_2 PF16884.5 KKF95438.1 - 7.4e-25 86.9 0.0 1.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KKF95438.1 - 2.3e-21 76.1 0.1 3.6e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKF95438.1 - 3e-05 25.1 0.0 7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Podoplanin PF05808.11 KKF95439.1 - 0.32 11.1 5.7 0.04 14.0 1.6 1.6 2 0 0 2 2 2 0 Podoplanin Phage_holin_2_4 PF16082.5 KKF95439.1 - 0.42 10.4 2.0 0.89 9.3 2.0 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Adeno_E1B_55K_N PF04623.12 KKF95439.1 - 1.2 9.9 12.2 3.8 8.3 8.3 2.4 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus VSP PF03302.13 KKF95439.1 - 2.8 6.7 17.3 1.6 7.5 15.5 1.5 1 1 0 1 1 1 0 Giardia variant-specific surface protein Cellulase PF00150.18 KKF95440.1 - 1.9e-39 135.8 0.0 2.6e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Alpha_GJ PF03229.13 KKF95440.1 - 3.1 8.3 13.0 6.2 7.4 13.0 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Asp PF00026.23 KKF95441.1 - 7.6e-38 130.7 0.2 5.3e-37 127.9 0.2 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKF95441.1 - 4.8e-07 30.2 1.8 2.6e-05 24.5 1.8 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TauD PF02668.16 KKF95442.1 - 3.5e-51 174.6 0.0 4.4e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KKF95443.1 - 3.9e-24 85.2 16.8 5.8e-24 84.7 16.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HMG_box PF00505.19 KKF95443.1 - 0.12 12.8 0.5 0.12 12.8 0.5 2.5 4 0 0 4 4 4 0 HMG (high mobility group) box Aldo_ket_red PF00248.21 KKF95444.1 - 3e-69 233.5 0.0 6.6e-65 219.2 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family Fungal_trans PF04082.18 KKF95444.1 - 5.4e-08 32.2 0.0 1.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF95444.1 - 6.3e-07 29.4 8.5 1.3e-06 28.4 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_TAC_10 PF10963.8 KKF95444.1 - 0.29 11.3 0.6 33 4.7 0.0 2.5 2 0 0 2 2 2 0 Phage tail assembly chaperone CDC45 PF02724.14 KKF95445.1 - 0.41 8.9 13.4 0.47 8.7 13.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KKF95445.1 - 3.4 5.8 16.4 4.2 5.5 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family Guanylate_kin PF00625.21 KKF95446.1 - 5.5e-62 208.7 0.0 6.2e-62 208.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 KKF95446.1 - 3e-06 27.3 0.1 0.00037 20.5 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KKF95446.1 - 9.5e-05 22.6 0.1 0.001 19.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKF95446.1 - 0.00045 20.8 0.2 0.0027 18.2 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KKF95446.1 - 0.0013 19.0 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KKF95446.1 - 0.0053 16.7 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase dNK PF01712.19 KKF95446.1 - 0.015 15.2 0.5 1 9.1 0.0 2.5 2 1 1 3 3 3 0 Deoxynucleoside kinase ABC_tran PF00005.27 KKF95446.1 - 0.027 15.0 0.3 0.091 13.3 0.3 2.2 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KKF95446.1 - 0.03 14.7 0.1 0.034 14.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KKF95446.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKF95446.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKF95446.1 - 0.16 12.2 0.3 1.9 8.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain zf-MYND PF01753.18 KKF95448.1 - 4.8e-08 33.0 19.6 1.7e-07 31.2 19.6 2.0 1 0 0 1 1 1 1 MYND finger SelP_N PF04592.14 KKF95448.1 - 0.43 10.0 28.3 1.9 7.8 14.4 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region CAF20 PF17052.5 KKF95448.1 - 1 9.5 7.1 0.065 13.4 1.0 2.0 2 0 0 2 2 2 0 Cap associated factor Macoilin PF09726.9 KKF95448.1 - 3.9 5.9 18.5 0.043 12.4 9.3 2.0 2 0 0 2 2 2 0 Macoilin family Zip PF02535.22 KKF95448.1 - 8.8 5.4 12.1 12 5.0 4.7 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Tfb5 PF06331.12 KKF95449.1 - 5.4e-26 90.4 1.2 5.8e-26 90.3 1.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ECH_1 PF00378.20 KKF95450.1 - 4.5e-40 137.5 0.0 1.1e-39 136.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKF95450.1 - 4.7e-27 95.4 0.0 2.1e-24 86.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Glyco_hydro_72 PF03198.14 KKF95451.1 - 8e-125 416.3 7.7 1e-124 415.9 7.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KKF95451.1 - 5.9e-07 29.2 0.7 1.1e-05 25.0 0.8 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KKF95451.1 - 0.00033 19.8 0.3 0.00084 18.5 0.3 1.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Dehydrin PF00257.19 KKF95451.1 - 0.019 15.5 5.6 0.034 14.7 5.6 1.5 1 0 0 1 1 1 0 Dehydrin PDZ_1 PF12812.7 KKF95451.1 - 0.037 14.1 0.0 0.96 9.5 0.0 2.9 2 0 0 2 2 2 0 PDZ-like domain Oxidored_q6 PF01058.22 KKF95452.1 - 1.3e-23 83.3 0.0 2.3e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit IRS PF02174.17 KKF95452.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) HECT PF00632.25 KKF95453.1 - 5.6e-96 321.6 0.0 7.3e-96 321.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KKF95453.1 - 2.5e-33 113.8 22.1 4.5e-12 45.8 3.8 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KKF95453.1 - 5.6e-20 71.5 0.0 1.4e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain PurS PF02700.14 KKF95453.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase RRM_1 PF00076.22 KKF95454.1 - 6.6e-17 61.1 0.0 9.9e-17 60.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.11 KKF95454.1 - 0.056 14.1 3.2 0.056 14.1 3.2 1.9 2 1 0 2 2 2 0 Glycine rich protein family Nup35_RRM_2 PF14605.6 KKF95454.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif V_ATPase_I PF01496.19 KKF95454.1 - 0.26 9.2 0.2 0.31 8.9 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ECSCR PF15820.5 KKF95456.1 - 1.1 9.1 0.0 1.1 9.1 0.0 3.3 3 1 1 4 4 4 0 Endothelial cell-specific chemotaxis regulator GMC_oxred_N PF00732.19 KKF95457.1 - 8.2e-45 153.4 0.0 2.3e-42 145.4 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKF95457.1 - 6e-34 117.6 0.0 1.5e-33 116.3 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KKF95457.1 - 0.021 14.1 0.2 0.069 12.4 0.2 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKF95457.1 - 0.04 13.0 4.2 0.37 9.8 4.2 2.0 1 1 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KKF95457.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKF95457.1 - 0.09 12.3 0.1 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Tctex-1 PF03645.13 KKF95458.1 - 9.9e-33 112.5 0.2 1.2e-32 112.2 0.2 1.1 1 0 0 1 1 1 1 Tctex-1 family APC_u15 PF16636.5 KKF95458.1 - 0.29 11.6 3.4 0.64 10.5 3.4 1.6 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 DUF202 PF02656.15 KKF95459.1 - 4.9e-16 58.9 4.1 1.3e-15 57.6 2.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Alba PF01918.21 KKF95460.1 - 0.00017 21.3 0.0 0.00043 20.0 0.0 1.6 1 0 0 1 1 1 1 Alba DUF4611 PF15387.6 KKF95460.1 - 2.3 8.5 7.7 3.5 7.9 1.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CENP-L PF13092.6 KKF95461.1 - 6.9e-12 45.9 0.8 1.9e-11 44.4 0.4 1.9 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 HET PF06985.11 KKF95462.1 - 1.2e-09 38.7 2.6 1.7e-05 25.2 0.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NAD_binding_7 PF13241.6 KKF95463.1 - 1.5e-30 105.7 0.1 2.3e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KKF95463.1 - 2.6e-28 97.4 0.0 4e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KKF95463.1 - 2.2e-14 52.6 0.0 4.2e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central TrkA_N PF02254.18 KKF95463.1 - 0.0054 17.0 0.1 0.0092 16.2 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.6 KKF95463.1 - 0.014 14.7 0.1 0.028 13.7 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KKF95463.1 - 0.048 13.0 0.7 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.20 KKF95463.1 - 0.082 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KKF95463.1 - 0.1 13.2 0.3 0.74 10.4 0.1 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MIF4G PF02854.19 KKF95464.1 - 3.7e-57 193.4 0.0 1.2e-30 106.7 0.0 3.2 3 1 0 3 3 3 2 MIF4G domain Upf2 PF04050.14 KKF95464.1 - 2.5e-41 141.6 1.0 2.5e-41 141.6 1.0 4.0 6 0 0 6 6 6 1 Up-frameshift suppressor 2 Pes-10 PF07149.11 KKF95464.1 - 6 5.8 13.3 13 4.7 13.3 1.5 1 0 0 1 1 1 0 Pes-10 DUF1729 PF08354.10 KKF95465.1 - 1.1e-155 517.9 0.0 1.7e-155 517.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KKF95465.1 - 6.8e-86 288.7 0.0 1.6e-84 284.1 0.0 2.9 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KKF95465.1 - 1.5e-53 180.5 0.0 3.5e-53 179.3 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 KKF95465.1 - 9.1e-39 132.4 0.0 3.2e-38 130.7 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta SAT PF16073.5 KKF95465.1 - 3.3e-37 128.5 0.0 9.5e-37 127.0 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KKF95465.1 - 2.6e-36 123.9 0.0 5.3e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKF95465.1 - 1.1e-22 80.6 0.0 3.8e-22 78.8 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 KKF95465.1 - 0.48 9.8 1.7 9.2 5.5 1.2 2.8 2 1 0 2 2 2 0 Nitronate monooxygenase FAS_I_H PF18314.1 KKF95466.1 - 5.8e-77 257.9 0.8 1e-76 257.1 0.0 1.9 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KKF95466.1 - 5.8e-75 251.1 0.0 1.2e-74 250.0 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KKF95466.1 - 2.3e-20 73.2 0.0 6e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KKF95466.1 - 7.6e-18 64.7 0.0 1.8e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KKF95466.1 - 3.7e-12 46.3 0.1 1.4e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KKF95466.1 - 0.0019 18.1 0.0 0.011 15.7 0.0 2.3 1 0 0 1 1 1 1 KR domain Amidohydro_1 PF01979.20 KKF95467.1 - 3.5e-72 243.6 0.0 4.1e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKF95467.1 - 2.5e-09 37.2 0.3 5.7e-08 32.7 0.0 2.3 2 1 0 2 2 2 1 Amidohydrolase family DNApol_Exo PF18136.1 KKF95468.1 - 8.2e-99 330.3 0.0 1.5e-98 329.4 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KKF95468.1 - 1.9e-55 188.5 0.0 4.3e-55 187.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family A PIF1 PF05970.14 KKF95469.1 - 7.3e-62 209.6 0.6 7e-50 170.2 0.1 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KKF95469.1 - 2.3e-22 79.6 0.0 4.1e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF95469.1 - 7e-10 39.4 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KKF95469.1 - 1.4e-05 24.7 0.0 4.5e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 KKF95469.1 - 7.2e-05 23.1 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain SH3_13 PF18335.1 KKF95469.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 KKF95469.1 - 0.0003 20.5 0.1 0.00076 19.3 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KKF95469.1 - 0.00054 20.4 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KKF95469.1 - 0.0015 18.9 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KKF95469.1 - 0.0018 18.1 0.2 0.18 11.5 0.0 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 KKF95469.1 - 0.002 16.2 0.1 0.0044 15.0 0.0 1.5 2 0 0 2 2 2 1 Helicase AAA_11 PF13086.6 KKF95469.1 - 0.0032 17.3 0.2 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KKF95469.1 - 0.0049 17.3 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 KKF95469.1 - 0.006 17.1 0.0 0.019 15.5 0.0 1.8 2 0 0 2 2 1 1 ABC transporter T2SSE PF00437.20 KKF95469.1 - 0.014 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 KKF95469.1 - 0.016 15.2 0.1 0.098 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 KKF95469.1 - 0.021 14.3 0.0 0.089 12.2 0.0 2.0 3 0 0 3 3 3 0 PhoH-like protein NACHT PF05729.12 KKF95469.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KKF95469.1 - 0.026 14.5 0.0 0.14 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KKF95469.1 - 0.042 13.0 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 KKF95469.1 - 0.046 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KKF95469.1 - 0.096 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KKF95469.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KKF95469.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TEX33 PF15400.6 KKF95469.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family Tyrosinase PF00264.20 KKF95470.1 - 0.067 13.5 3.4 0.097 12.9 3.4 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase Plasmodium_Vir PF05795.11 KKF95470.1 - 1.1 8.6 4.2 1.4 8.3 4.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Spore_coat_CotO PF14153.6 KKF95470.1 - 2.5 8.0 19.9 3.8 7.4 19.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Raftlin PF15250.6 KKF95470.1 - 3.9 6.1 8.6 5.2 5.7 8.6 1.1 1 0 0 1 1 1 0 Raftlin Asp-B-Hydro_N PF05279.11 KKF95470.1 - 5.2 7.1 18.7 7.1 6.6 18.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Vps26 PF03643.15 KKF95471.1 - 1.3e-129 431.0 0.5 1.6e-129 430.8 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KKF95471.1 - 0.00039 20.5 0.8 0.53 10.3 0.0 3.5 2 1 2 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KKF95471.1 - 0.0067 16.9 0.0 0.067 13.6 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain IL17R_D_N PF16742.5 KKF95471.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Nup160 PF11715.8 KKF95472.1 - 2.5e-123 412.6 1.8 3.6e-123 412.0 1.8 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_7 PF13176.6 KKF95472.1 - 0.036 14.1 0.1 0.5 10.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Rad51 PF08423.11 KKF95473.1 - 6.4e-112 372.9 0.3 2.2e-75 253.2 0.2 2.1 1 1 1 2 2 2 2 Rad51 AAA_25 PF13481.6 KKF95473.1 - 3.6e-06 26.7 0.0 5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KKF95473.1 - 4.5e-06 27.2 0.9 2.6e-05 24.7 0.3 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.21 KKF95473.1 - 2.3e-05 24.0 0.0 5.9e-05 22.7 0.0 1.6 1 1 1 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 KKF95473.1 - 0.00076 18.9 0.2 0.0014 18.0 0.2 1.6 1 1 0 1 1 1 1 KaiC HSP20 PF00011.21 KKF95474.1 - 3.5e-16 59.2 0.2 3.7e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KKF95474.1 - 3.1e-05 23.4 0.0 0.0023 17.5 0.0 2.4 2 0 0 2 2 2 1 HSP20-like domain found in ArsA F_actin_bund_C PF18060.1 KKF95474.1 - 0.09 12.9 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 F actin bundling C terminal Ndc1_Nup PF09531.10 KKF95474.1 - 1.5 7.4 4.2 2.2 6.9 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 KKF95475.1 - 6.4e-62 209.3 0.0 8.1e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95475.1 - 2.3e-32 112.3 0.0 3.4e-32 111.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKF95475.1 - 0.045 12.7 0.0 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 KKF95475.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Sec10 PF07393.11 KKF95476.1 - 2.6e-147 492.3 0.0 3.2e-147 491.9 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KKF95476.1 - 4.4e-07 29.7 0.1 1.1e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKF95476.1 - 3.5e-05 23.6 0.3 7.5e-05 22.5 0.3 1.4 1 0 0 1 1 1 1 F-box domain AA_kinase PF00696.28 KKF95477.1 - 1e-41 143.1 0.4 2.9e-41 141.7 0.1 1.8 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 KKF95477.1 - 1.3e-13 50.5 1.1 9.5e-07 28.5 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KKF95477.1 - 9.3e-13 47.8 3.3 2.9e-08 33.4 0.3 2.6 2 0 0 2 2 2 2 ACT domain RFX_DNA_binding PF02257.15 KKF95478.1 - 5.6e-28 97.4 0.1 1.6e-27 96.0 0.1 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain TFIIA PF03153.13 KKF95478.1 - 0.95 9.4 58.6 0.86 9.5 45.7 2.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TB2_DP1_HVA22 PF03134.19 KKF95479.1 - 5.4e-27 93.5 8.8 8.7e-27 92.9 8.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mid1 PF12929.7 KKF95480.1 - 2.9e-139 465.0 4.8 3.7e-139 464.6 4.8 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KKF95480.1 - 3.2e-05 24.5 4.2 0.0042 17.7 0.8 2.5 2 0 0 2 2 2 2 Fz domain zf-RING_2 PF13639.6 KKF95481.1 - 1.9e-09 37.7 12.9 3.5e-09 36.9 12.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KKF95481.1 - 5.5e-09 35.7 9.8 1.2e-08 34.7 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKF95481.1 - 1.5e-08 34.3 13.2 3e-08 33.4 13.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKF95481.1 - 1.4e-07 31.3 13.6 2.6e-07 30.4 13.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKF95481.1 - 6.3e-07 29.2 9.2 1.8e-06 27.7 9.2 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KKF95481.1 - 9.7e-07 29.0 10.0 1.9e-06 28.0 10.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KKF95481.1 - 1.2e-05 25.2 9.1 2.9e-05 24.0 9.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKF95481.1 - 0.00013 21.9 13.7 0.00033 20.6 13.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.31 KKF95481.1 - 0.0007 19.9 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Baculo_IE-1 PF05290.11 KKF95481.1 - 0.0033 17.4 1.2 0.0079 16.1 1.2 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 KKF95481.1 - 0.0053 16.9 10.0 0.011 15.9 10.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KKF95481.1 - 0.033 14.0 8.6 0.096 12.5 5.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KKF95481.1 - 0.14 12.2 9.5 0.27 11.3 9.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.12 KKF95481.1 - 0.85 9.6 7.8 1.6 8.8 7.8 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-RING_10 PF16685.5 KKF95481.1 - 0.95 9.6 8.8 3.9 7.7 8.9 1.9 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-B_box PF00643.24 KKF95481.1 - 3 8.1 10.4 5.8 7.2 10.4 1.4 1 0 0 1 1 1 0 B-box zinc finger DZR PF12773.7 KKF95481.1 - 3.8 7.6 6.9 8.3 6.5 6.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon IGR PF09597.10 KKF95482.1 - 7.7e-24 83.6 0.1 1.4e-23 82.7 0.1 1.5 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.30 KKF95482.1 - 0.0069 16.8 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SMAP PF15477.6 KKF95483.1 - 6.2e-11 43.1 5.4 6.2e-11 43.1 5.4 4.6 2 1 0 2 2 2 1 Small acidic protein family RAMP4 PF06624.12 KKF95484.1 - 7.4e-17 61.2 0.4 8.1e-17 61.0 0.4 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 TRAP_alpha PF03896.16 KKF95485.1 - 4.2e-08 32.7 0.0 5.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Omp28 PF11551.8 KKF95485.1 - 0.059 13.2 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein Omp28 Med5 PF08689.10 KKF95487.1 - 1.1e-80 271.9 0.0 5.4e-80 269.6 0.0 1.8 1 1 0 1 1 1 1 Mediator complex subunit Med5 Phage_clamp_A PF16790.5 KKF95487.1 - 0.17 12.3 0.0 0.49 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage clamp loader A subunit ArgJ PF01960.18 KKF95488.1 - 1.3e-147 491.4 1.3 2e-147 490.8 1.3 1.3 1 0 0 1 1 1 1 ArgJ family IGPD PF00475.18 KKF95488.1 - 6.7e-58 195.1 2.4 1.1e-57 194.4 2.4 1.4 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Pkinase PF00069.25 KKF95489.1 - 1.1e-35 123.3 0.0 2.2e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95489.1 - 3.1e-25 88.9 0.0 5.2e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF95489.1 - 0.00034 20.0 0.0 0.00082 18.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KKF95489.1 - 0.37 10.7 2.5 0.53 10.2 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family FAA_hydrolase_N PF09298.11 KKF95489.1 - 3.1 8.0 4.9 4.6 7.5 2.2 2.4 1 1 2 3 3 3 0 Fumarylacetoacetase N-terminal BTB PF00651.31 KKF95490.1 - 2.4e-17 63.2 0.0 1.6e-08 34.8 0.3 3.1 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 KKF95490.1 - 4.2e-09 36.8 0.1 1.7e-08 34.8 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKF95490.1 - 2.2e-07 31.4 0.0 5.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKF95490.1 - 5.9e-07 29.6 0.0 1.7e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KKF95490.1 - 2.4e-06 27.7 0.2 0.024 15.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KKF95490.1 - 8.6e-06 25.7 0.5 0.061 13.9 0.1 3.3 2 0 0 2 2 2 2 Ankyrin repeat ABC_tran_CTD PF16326.5 KKF95490.1 - 2.1 8.7 4.2 2.3 8.5 2.1 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF853 PF05872.12 KKF95491.1 - 0.012 14.3 1.1 0.019 13.6 1.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) HDV_ag PF01517.18 KKF95491.1 - 0.051 13.4 0.5 0.11 12.3 0.5 1.5 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen SCO1-SenC PF02630.14 KKF95492.1 - 5.3e-48 162.3 0.0 1.6e-47 160.8 0.0 1.8 2 0 0 2 2 2 1 SCO1/SenC Hydrolase_6 PF13344.6 KKF95492.1 - 4.2e-23 81.4 0.0 9e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKF95492.1 - 1.2e-05 25.2 0.0 4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like AhpC-TSA PF00578.21 KKF95492.1 - 0.0044 16.9 0.0 0.013 15.4 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKF95492.1 - 0.013 15.2 0.0 0.13 11.9 0.0 2.4 2 1 0 2 2 2 0 Redoxin Hydrolase PF00702.26 KKF95492.1 - 0.013 15.8 0.0 6.5 7.0 0.0 3.2 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Thioredoxin_8 PF13905.6 KKF95492.1 - 0.016 15.6 0.0 0.044 14.1 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like HAD_2 PF13419.6 KKF95492.1 - 0.046 13.8 0.0 22 5.1 0.0 2.8 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Choline_kinase PF01633.20 KKF95493.1 - 1.7e-59 201.0 0.0 5.4e-59 199.3 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KKF95493.1 - 2.9e-06 27.4 0.2 6.9e-06 26.1 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family TRAM_LAG1_CLN8 PF03798.16 KKF95494.1 - 5.5e-45 153.5 21.5 5.5e-45 153.5 21.5 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KKF95494.1 - 3.4e-21 74.7 0.6 3.4e-21 74.7 0.6 2.0 2 0 0 2 2 2 1 TRAM1-like protein Bax1-I PF01027.20 KKF95495.1 - 4.5e-47 160.6 28.4 5.2e-47 160.4 28.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Septin PF00735.18 KKF95496.1 - 1e-106 356.4 0.1 2.1e-106 355.3 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KKF95496.1 - 2.9e-05 24.1 0.0 7.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKF95496.1 - 0.0014 18.6 0.1 0.0014 18.6 0.1 2.1 3 0 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 KKF95496.1 - 0.0033 17.5 3.8 2 8.5 0.0 3.2 2 1 1 3 3 3 2 Dynamin family AAA_23 PF13476.6 KKF95496.1 - 0.042 14.4 2.7 6.8 7.1 2.7 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KKF95496.1 - 0.071 12.6 0.1 0.44 10.0 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KKF95496.1 - 0.079 13.2 0.3 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KKF95496.1 - 2.2 7.6 4.6 0.3 10.4 0.3 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.32 KKF95497.1 - 5.9e-08 33.2 0.0 0.061 14.2 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF95497.1 - 0.00061 20.0 0.0 0.025 14.8 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF95497.1 - 0.0093 15.0 0.1 0.44 9.4 0.0 2.2 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KKF95497.1 - 0.012 15.6 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KKF95497.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 KKF95497.1 - 0.31 9.0 0.0 0.47 8.4 0.0 1.2 1 0 0 1 1 1 0 IKI3 family RRM_1 PF00076.22 KKF95498.1 - 2.4e-14 52.9 0.0 2.3e-13 49.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKF95498.1 - 0.0061 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif DLIC PF05783.11 KKF95499.1 - 2.4e-25 89.3 1.1 5.8e-22 78.2 0.1 3.5 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Thioredox_DsbH PF03190.15 KKF95500.1 - 7.8e-57 191.8 0.0 1.2e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KKF95500.1 - 0.0018 18.4 0.0 0.0047 17.1 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like CNH PF00780.22 KKF95501.1 - 1.6e-77 260.8 0.0 8.3e-77 258.5 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KKF95501.1 - 6.3e-43 146.1 2.7 1.2e-42 145.2 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.20 KKF95501.1 - 1.9e-34 119.5 0.0 1.9e-34 119.5 0.0 2.0 3 0 0 3 3 3 1 RhoGEF domain DEP PF00610.21 KKF95501.1 - 6.9e-15 54.9 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RR_TM4-6 PF06459.12 KKF95501.1 - 0.043 13.6 1.8 0.085 12.7 1.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4834 PF16118.5 KKF95501.1 - 0.77 10.8 3.8 5.9 7.9 3.8 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ATP-synt_C PF00137.21 KKF95502.1 - 1.7e-28 98.7 35.8 6.8e-18 64.8 13.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Fasciclin PF02469.22 KKF95504.1 - 1.5e-37 128.7 0.0 2.5e-17 63.3 0.0 2.6 2 1 0 2 2 2 2 Fasciclin domain Pal1 PF08316.11 KKF95505.1 - 1.7e-40 138.9 2.5 9.6e-40 136.5 2.5 2.1 1 1 0 1 1 1 1 Pal1 cell morphology protein tRNA-synt_2 PF00152.20 KKF95507.1 - 9.7e-69 231.8 0.0 1.2e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKF95507.1 - 3.7e-06 26.8 0.0 7.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Borrelia_P83 PF05262.11 KKF95507.1 - 0.027 13.0 2.5 0.036 12.6 2.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Tup_N PF08581.10 KKF95508.1 - 0.0051 17.1 2.5 0.0051 17.1 2.5 8.2 6 4 2 9 9 9 2 Tup N-terminal MtrG PF04210.13 KKF95508.1 - 0.11 12.3 0.6 9.4 6.2 0.1 3.6 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4968 PF16338.5 KKF95508.1 - 0.88 9.9 5.5 0.38 11.1 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4968) Nas2_N PF18265.1 KKF95508.1 - 2.1 8.3 5.5 7.1 6.6 0.0 4.3 4 0 0 4 4 4 0 Nas2 N_terminal domain Nse4_C PF08743.10 KKF95509.1 - 9.8e-26 89.9 0.0 1.8e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KKF95509.1 - 1.4e-14 53.9 2.5 2.7e-14 53.0 0.0 2.5 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE PI3Ka PF00613.20 KKF95510.1 - 7.5e-58 195.0 0.3 1.4e-57 194.1 0.3 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KKF95510.1 - 1.4e-46 159.3 0.0 7.3e-44 150.5 0.1 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KKF95510.1 - 9.3e-32 109.9 0.0 1.6e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF3292 PF11696.8 KKF95510.1 - 0.00068 18.2 0.0 0.001 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) JHY PF15261.6 KKF95510.1 - 0.7 10.6 2.4 1.2 9.9 0.3 2.2 2 0 0 2 2 2 0 Jhy protein RWD PF05773.22 KKF95511.1 - 0.0039 17.5 0.0 0.0091 16.3 0.0 1.6 1 0 0 1 1 1 1 RWD domain Zn_ribbon_17 PF17120.5 KKF95511.1 - 0.017 14.7 7.6 0.033 13.8 7.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Mitovir_RNA_pol PF05919.11 KKF95511.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase adh_short PF00106.25 KKF95512.1 - 2e-48 164.4 1.3 2.7e-48 164.0 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF95512.1 - 1.4e-34 119.7 0.9 1.8e-34 119.3 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF95512.1 - 1.6e-12 47.7 0.3 2.3e-12 47.2 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKF95512.1 - 0.00011 21.8 0.2 0.002 17.6 0.3 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKF95512.1 - 0.00014 21.5 1.0 0.00019 21.0 0.4 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KKF95512.1 - 0.00019 21.4 0.1 0.00027 20.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KKF95512.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RVT_1 PF00078.27 KKF95513.1 - 6.5e-26 91.2 0.3 1.2e-25 90.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KKF95513.1 - 8.8e-21 73.8 0.0 2.6e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KKF95513.1 - 8.7e-11 42.0 0.0 2.3e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PI-PLC-X PF00388.19 KKF95514.1 - 9e-09 35.1 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-X PF00388.19 KKF95516.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.5 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-X PF00388.19 KKF95517.1 - 1.4e-08 34.5 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Rep_fac_C PF08542.11 KKF95517.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Replication factor C C-terminal domain Pectate_lyase_3 PF12708.7 KKF95518.1 - 5.2e-101 336.9 19.4 7.3e-85 284.2 7.6 3.0 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KKF95518.1 - 3.7e-07 29.7 1.2 0.033 13.9 0.1 3.6 4 0 0 4 4 4 2 N terminal extension of bacteriophage endosialidase PI-PLC-X PF00388.19 KKF95519.1 - 2.3e-09 37.0 0.0 4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-X PF00388.19 KKF95520.1 - 1.6e-11 44.0 0.0 2.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-X PF00388.19 KKF95521.1 - 1.3e-12 47.5 0.0 2.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Pro_isomerase PF00160.21 KKF95522.1 - 1.2e-32 113.3 0.1 3.7e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KKF95522.1 - 1.1e-15 57.2 0.0 2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.6 KKF95524.1 - 2.1e-65 221.2 39.0 2.8e-65 220.8 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKF95524.1 - 3.6e-20 72.0 33.3 4.7e-20 71.6 33.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.11 KKF95524.1 - 0.12 12.5 1.0 0.56 10.3 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF962) RPA43_OB PF17875.1 KKF95525.1 - 4.2e-32 111.4 0.1 4.2e-32 111.4 0.1 4.0 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I SOG2 PF10428.9 KKF95525.1 - 1.5 8.0 17.7 1.8 7.7 17.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ecl1 PF12855.7 KKF95525.1 - 2.3 9.3 22.2 4.2 8.5 22.2 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins MFS_1 PF07690.16 KKF95526.1 - 8e-19 67.8 36.3 6e-10 38.6 2.9 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKF95526.1 - 6.6e-06 24.9 11.4 6.6e-06 24.9 11.4 2.4 3 0 0 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 KKF95526.1 - 0.00016 20.7 7.5 0.00016 20.7 7.5 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KKF95526.1 - 0.0052 15.7 12.9 0.0056 15.6 6.2 2.7 2 1 0 2 2 2 1 MFS_1 like family OATP PF03137.20 KKF95526.1 - 0.019 13.3 3.3 0.019 13.3 2.3 1.4 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SieB PF14163.6 KKF95526.1 - 7.5 6.0 6.4 12 5.4 0.1 2.8 3 0 0 3 3 3 0 Super-infection exclusion protein B Cu_amine_oxid PF01179.20 KKF95527.1 - 1.4e-126 422.8 6.9 1.7e-126 422.5 6.9 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KKF95527.1 - 4.7e-34 116.0 0.8 1e-33 114.9 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) DUF3455 PF11937.8 KKF95528.1 - 1.9e-21 77.1 0.0 3.4e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2207 PF09972.9 KKF95528.1 - 0.026 13.3 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 KKF95528.1 - 0.052 13.3 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TRAP_alpha PF03896.16 KKF95528.1 - 0.19 10.9 3.4 0.28 10.4 3.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pkinase PF00069.25 KKF95529.1 - 1e-68 231.6 0.0 1.2e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95529.1 - 4.3e-31 108.2 0.0 6.5e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKF95529.1 - 0.013 14.5 0.0 0.028 13.4 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KKF95529.1 - 0.025 14.0 0.1 0.049 13.0 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKF95529.1 - 0.05 13.5 0.2 0.17 11.8 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family LMWPc PF01451.21 KKF95530.1 - 3.4e-28 98.8 0.0 4e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.25 KKF95531.1 - 5.4e-27 94.8 0.0 6.5e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95531.1 - 2.5e-14 53.2 0.0 3.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKF95531.1 - 3.7e-09 35.9 0.0 5e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KKF95531.1 - 8.2e-05 22.6 0.0 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KKF95533.1 - 4.2e-61 206.6 0.0 2.5e-36 125.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95533.1 - 1e-25 90.5 0.0 2.3e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KKF95533.1 - 0.024 14.6 0.9 0.33 10.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKF95533.1 - 0.048 12.6 0.5 0.068 12.1 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 KKF95533.1 - 0.056 12.8 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 KKF95533.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RabGAP-TBC PF00566.18 KKF95534.1 - 1.8e-46 158.5 0.0 3.4e-46 157.6 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KKF95534.1 - 4.7e-05 23.0 0.9 0.39 10.8 0.2 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KKF95534.1 - 0.00071 18.9 1.5 1.6 8.4 0.3 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KKF95534.1 - 0.0017 18.7 1.3 0.008 16.6 0.8 2.4 2 0 0 2 2 2 1 EF-hand domain pair CNH PF00780.22 KKF95535.1 - 1.3e-60 205.4 0.0 1.8e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KKF95535.1 - 1.2e-32 113.6 0.6 2.2e-32 112.8 0.6 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KKF95535.1 - 9.4e-15 54.9 0.0 2.3e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KKF95535.1 - 1.5e-05 25.4 0.0 0.0011 19.5 0.2 3.3 2 1 0 2 2 2 1 PH domain PH_16 PF17838.1 KKF95535.1 - 0.0068 16.2 0.1 2.8 7.8 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_13 PF16652.5 KKF95535.1 - 0.14 12.0 0.4 0.65 9.8 0.4 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Sod_Cu PF00080.20 KKF95536.1 - 3.5e-46 156.9 6.0 4e-46 156.7 6.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.17 KKF95537.1 - 1.6e-67 224.8 0.0 2.4e-20 73.0 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KKF95537.1 - 3e-24 85.4 0.0 2.5e-23 82.4 0.0 2.1 2 0 0 2 2 2 1 Tudor domain TAL_FSA PF00923.19 KKF95538.1 - 1e-89 300.7 0.5 1.1e-89 300.6 0.5 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase tRNA-synt_1c PF00749.21 KKF95540.1 - 3.3e-96 321.9 0.0 3.3e-96 321.9 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KKF95540.1 - 1.2e-31 109.9 0.0 4.2e-31 108.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KKF95540.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Pet191_N PF10203.9 KKF95541.1 - 1.1e-25 89.7 3.5 1.5e-25 89.3 3.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 KKF95541.1 - 0.012 15.6 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 0 COBRA-like protein Clusterin PF01093.17 KKF95541.1 - 0.031 13.3 0.9 0.047 12.8 0.9 1.2 1 0 0 1 1 1 0 Clusterin CX9C PF16860.5 KKF95541.1 - 0.91 9.6 5.7 0.97 9.5 0.8 2.6 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Abhydro_lipase PF04083.16 KKF95542.1 - 1.6e-22 78.9 0.3 2.7e-22 78.1 0.3 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KKF95542.1 - 4.9e-22 78.8 0.2 7.2e-18 65.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKF95542.1 - 3.2e-06 26.6 0.0 0.00044 19.6 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KKF95542.1 - 0.00033 20.4 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KKF95542.1 - 0.16 11.7 0.0 21 4.8 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase NFACT-C PF11923.8 KKF95543.1 - 2.2e-37 127.2 0.2 2.2e-37 127.2 0.2 2.8 3 0 0 3 3 3 1 NFACT protein C-terminal domain FbpA PF05833.11 KKF95543.1 - 6.8e-30 104.2 8.0 6.8e-30 104.2 8.0 2.6 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KKF95543.1 - 2.5e-25 89.2 0.0 7.8e-25 87.6 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain Methyltransf_23 PF13489.6 KKF95543.1 - 1.9e-18 66.8 0.1 6.7e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF95543.1 - 1.2e-08 35.6 0.0 5.3e-08 33.5 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF95543.1 - 2.8e-06 27.9 0.0 1.1e-05 26.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF95543.1 - 1e-05 25.4 0.0 0.00024 20.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF95543.1 - 0.00017 22.3 0.0 0.068 13.9 0.0 4.1 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KKF95543.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MOFRL PF05161.13 KKF95544.1 - 0.022 14.9 0.9 0.075 13.2 0.9 1.8 1 0 0 1 1 1 0 MOFRL family Cluap1 PF10234.9 KKF95544.1 - 0.087 12.2 3.6 0.15 11.4 3.6 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 PA26 PF04636.13 KKF95544.1 - 0.12 11.3 2.6 0.22 10.4 2.6 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FRG1 PF06229.12 KKF95544.1 - 1.1 8.9 4.7 0.34 10.6 0.5 2.0 2 0 0 2 2 2 0 FRG1-like domain ADH_zinc_N PF00107.26 KKF95545.1 - 1.2e-14 54.4 0.2 2.1e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKF95545.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Ribosomal_L12 PF00542.19 KKF95545.1 - 0.055 13.8 0.2 0.098 13.0 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain UQ_con PF00179.26 KKF95547.1 - 8.6e-48 161.5 0.0 9.7e-48 161.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKF95547.1 - 0.00057 19.6 0.0 0.00077 19.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KKF95547.1 - 0.0086 15.9 0.1 0.017 15.0 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KKF95547.1 - 0.079 13.3 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain MFS_1 PF07690.16 KKF95548.1 - 2.9e-17 62.6 33.0 9.5e-17 60.9 23.2 3.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5391 PF17369.2 KKF95548.1 - 0.0025 17.9 1.8 0.0096 16.0 1.8 2.1 1 0 0 1 1 1 1 Family of unknown function (DUF5391) SLT PF01464.20 KKF95548.1 - 0.073 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Transglycosylase SLT domain Sugar_tr PF00083.24 KKF95548.1 - 0.17 10.8 30.0 0.68 8.7 13.4 3.4 2 2 0 2 2 2 0 Sugar (and other) transporter Ribosomal_S24e PF01282.19 KKF95549.1 - 1.9e-34 117.4 0.1 3.7e-34 116.5 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e GTP_cyclohydro2 PF00925.20 KKF95550.1 - 2.2e-58 196.5 0.0 3.9e-58 195.7 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II NDUF_B7 PF05676.13 KKF95551.1 - 1.5e-29 101.5 6.9 1.9e-29 101.1 6.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Sugar_tr PF00083.24 KKF95552.1 - 2.8e-74 250.6 19.6 2.1e-72 244.5 19.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF95552.1 - 1.3e-28 99.9 59.8 1.1e-21 77.2 33.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKF95552.1 - 0.00014 20.4 4.0 0.00014 20.4 4.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BRCT_assoc PF12820.7 KKF95552.1 - 0.27 11.0 0.0 0.46 10.3 0.0 1.2 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT Actin PF00022.19 KKF95553.1 - 1.9e-112 375.8 0.0 7.9e-112 373.8 0.0 1.7 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 KKF95553.1 - 0.01 15.1 0.2 0.054 12.7 0.1 2.0 2 0 0 2 2 2 0 Putative actin-like family MreB_Mbl PF06723.13 KKF95553.1 - 0.027 13.3 0.0 0.29 9.9 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.25 KKF95554.1 - 3.8e-63 213.3 0.0 4.9e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95554.1 - 1.1e-29 103.6 0.0 3.7e-29 101.8 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KKF95554.1 - 0.096 12.6 0.1 0.81 9.6 0.0 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKF95554.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Arf PF00025.21 KKF95555.1 - 1.4e-74 249.3 0.1 1.6e-74 249.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKF95555.1 - 3.4e-14 53.1 0.0 4.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKF95555.1 - 4e-13 49.3 0.0 4.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KKF95555.1 - 9.4e-13 48.0 1.3 1.2e-08 34.6 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KKF95555.1 - 3.3e-11 43.0 0.0 4.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKF95555.1 - 7.2e-11 41.8 0.0 9.1e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKF95555.1 - 0.00087 19.4 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KKF95555.1 - 0.058 12.7 0.1 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Methyltrn_RNA_3 PF02598.17 KKF95555.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase CRISPR_Cas2 PF09827.9 KKF95555.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 MobB PF03205.14 KKF95555.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1325 PF07039.11 KKF95556.1 - 1.4e-33 115.8 0.0 2.6e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KKF95556.1 - 0.0032 17.3 0.0 0.0083 16.0 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KKF95556.1 - 0.02 14.9 0.1 0.051 13.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) CDC45 PF02724.14 KKF95556.1 - 0.12 10.6 15.7 0.17 10.1 15.7 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 KKF95556.1 - 0.48 10.2 12.6 0.8 9.5 12.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KKF95556.1 - 1.7 7.4 11.1 2.2 6.9 11.1 1.2 1 0 0 1 1 1 0 Presenilin Pneumo_att_G PF05539.11 KKF95556.1 - 1.8 8.1 5.5 2.9 7.4 5.5 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Afi1 PF07792.12 KKF95556.1 - 3.7 8.0 7.6 13 6.3 7.6 2.0 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NPR3 PF03666.13 KKF95556.1 - 4.7 5.9 11.3 6.4 5.5 11.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1682 PF07946.14 KKF95556.1 - 6.1 5.9 23.3 8.3 5.5 23.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PMI_typeI PF01238.21 KKF95557.1 - 6.6e-118 394.1 0.0 1.5e-116 389.7 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KKF95557.1 - 0.042 13.6 0.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 Cupin domain Zn_clus PF00172.18 KKF95558.1 - 2.8e-07 30.5 7.2 4.5e-07 29.9 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCP_MauG PF03150.14 KKF95558.1 - 0.0072 17.0 3.4 0.021 15.5 3.4 1.7 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase Cnl2_NKP2 PF09447.10 KKF95560.1 - 9.4e-27 93.0 0.5 3.3e-26 91.2 0.2 2.0 2 0 0 2 2 2 1 Cnl2/NKP2 family protein SYCE1 PF15233.6 KKF95560.1 - 0.013 15.6 0.1 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF4407 PF14362.6 KKF95560.1 - 0.017 14.5 1.8 0.021 14.2 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Spc19 PF08287.11 KKF95560.1 - 0.059 13.3 2.1 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 Spc19 Prominin PF05478.11 KKF95560.1 - 0.11 10.4 0.3 0.72 7.7 0.0 1.8 1 1 1 2 2 2 0 Prominin MRG PF05712.13 KKF95561.1 - 1.3e-56 191.1 0.1 1.7e-56 190.7 0.1 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KKF95561.1 - 9e-07 28.7 1.7 1.5e-06 27.9 1.7 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Ribosomal_L30 PF00327.20 KKF95562.1 - 1.1e-14 54.1 0.1 1.4e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Citrate_synt PF00285.21 KKF95563.1 - 1e-19 70.9 0.0 1.4e-16 60.6 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KKF95563.1 - 1.4e-19 70.5 0.1 5.2e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KKF95563.1 - 2.9e-14 53.1 0.1 6.5e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KKF95563.1 - 6e-05 22.9 0.0 0.002 17.9 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKF95563.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Citrate_bind PF16114.5 KKF95564.1 - 1.9e-87 291.3 0.0 2.7e-87 290.9 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KKF95564.1 - 1.5e-08 34.5 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KKF95564.1 - 0.052 11.7 0.0 0.077 11.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Glyco_hydro_72 PF03198.14 KKF95565.1 - 2.2e-113 378.7 0.1 3.4e-113 378.1 0.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KKF95565.1 - 0.044 13.2 0.0 0.53 9.7 0.0 2.1 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Lys PF00062.20 KKF95565.1 - 0.22 11.8 0.4 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 C-type lysozyme/alpha-lactalbumin family SRC-1 PF08832.10 KKF95565.1 - 5.5 8.1 5.1 62 4.7 0.0 2.5 2 0 0 2 2 2 0 Steroid receptor coactivator Q_salvage PF10343.9 KKF95566.1 - 1.4e-120 402.2 0.0 1.7e-120 401.9 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Septin PF00735.18 KKF95567.1 - 1.1e-112 375.9 1.5 1.3e-112 375.7 1.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KKF95567.1 - 1.7e-07 31.3 0.0 3.2e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKF95567.1 - 3e-05 23.7 0.8 0.0067 16.0 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKF95567.1 - 7.6e-05 22.7 0.7 0.00068 19.6 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KKF95567.1 - 8.1e-05 22.0 0.0 0.00016 21.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KKF95567.1 - 0.0012 18.9 0.3 0.74 9.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.6 KKF95567.1 - 0.005 17.1 0.0 0.012 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KKF95567.1 - 0.005 16.4 0.1 0.028 13.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 KKF95567.1 - 0.0089 16.4 0.0 0.016 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KKF95567.1 - 0.012 15.0 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.22 KKF95567.1 - 0.012 14.8 0.1 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 KKF95567.1 - 0.026 14.7 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KKF95567.1 - 0.03 14.8 0.6 0.053 14.0 0.3 1.8 1 1 0 1 1 1 0 ABC transporter Ras PF00071.22 KKF95567.1 - 0.044 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Ras family Microtub_bd PF16796.5 KKF95567.1 - 0.053 13.5 0.4 0.33 10.9 0.0 2.3 3 0 0 3 3 3 0 Microtubule binding G-alpha PF00503.20 KKF95567.1 - 0.064 12.4 0.8 0.19 10.8 0.7 1.9 1 1 0 1 1 1 0 G-protein alpha subunit T2SSE PF00437.20 KKF95567.1 - 0.13 11.2 0.1 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ThiF PF00899.21 KKF95568.1 - 1e-59 201.9 0.0 1.2e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KKF95568.1 - 8.8e-21 74.3 0.3 2.2e-20 73.0 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KKF95568.1 - 2.7e-09 37.4 2.9 9.4e-06 25.7 0.4 2.6 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KKF95568.1 - 0.0091 16.4 0.0 0.039 14.4 0.0 2.1 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 KKF95568.1 - 0.057 14.0 0.5 21 5.8 0.0 3.8 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase FeoA PF04023.14 KKF95568.1 - 0.13 12.5 0.0 0.47 10.8 0.0 1.9 2 0 0 2 2 2 0 FeoA domain PAP2 PF01569.21 KKF95569.1 - 5.2e-20 71.6 1.7 5.2e-20 71.6 1.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KKF95569.1 - 0.00018 21.3 1.3 0.00018 21.3 1.3 2.5 2 1 1 3 3 3 1 PAP2 superfamily JmjC PF02373.22 KKF95570.1 - 2.4e-36 124.6 0.6 4.4e-36 123.8 0.6 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.6 KKF95570.1 - 1.2e-16 60.7 5.5 1.2e-16 60.7 5.5 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KKF95570.1 - 3.6e-16 59.3 7.1 8e-16 58.2 7.1 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.17 KKF95570.1 - 5.9e-14 51.7 1.9 9.7e-14 51.1 0.6 2.1 2 0 0 2 2 2 1 jmjN domain CDC45 PF02724.14 KKF95570.1 - 0.0011 17.4 0.2 0.0011 17.4 0.2 2.1 2 0 0 2 2 2 1 CDC45-like protein Spt5_N PF11942.8 KKF95570.1 - 0.018 16.0 4.7 0.018 16.0 4.7 3.0 3 1 0 3 3 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4808 PF16066.5 KKF95570.1 - 0.17 12.4 0.6 0.48 11.0 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) Zn_ribbon_17 PF17120.5 KKF95570.1 - 0.7 9.6 9.8 6.1 6.6 4.9 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type SDA1 PF05285.12 KKF95570.1 - 2.2 7.6 21.7 0.015 14.8 3.9 2.3 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 KKF95570.1 - 4.2 5.5 16.1 0.25 9.5 3.5 2.1 2 0 0 2 2 2 0 Nop14-like family CAC1F_C PF16885.5 KKF95570.1 - 7.1 6.2 16.2 0.17 11.6 1.1 2.3 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term Spore_III_AF PF09581.10 KKF95570.1 - 9.2 6.3 8.2 1 9.3 1.4 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DUF4439 PF14530.6 KKF95571.1 - 0.08 13.6 0.0 0.18 12.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4439) Fungal_trans PF04082.18 KKF95573.1 - 1.1e-11 44.3 0.0 1.9e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHR-2 PF06920.13 KKF95574.1 - 5.3e-34 117.8 2.1 1.1e-32 113.4 2.1 2.2 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 KKF95574.1 - 1.3e-05 24.3 0.5 5.4e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 DOCK N-terminus DUF2470 PF10615.9 KKF95576.1 - 6.2e-21 74.8 0.1 9.2e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) SNO PF01174.19 KKF95577.1 - 4.1e-54 183.3 0.0 1.9e-53 181.1 0.0 1.8 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KKF95577.1 - 1.3e-09 38.0 0.0 1.5e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KKF95577.1 - 0.00076 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 KKF95577.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KKF95577.1 - 0.054 13.2 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like Cupin_6 PF12852.7 KKF95577.1 - 0.099 12.4 0.0 0.31 10.7 0.0 1.8 1 1 0 1 1 1 0 Cupin Peptidase_C26 PF07722.13 KKF95577.1 - 0.12 12.2 0.1 0.48 10.1 0.0 2.0 2 1 0 2 2 2 0 Peptidase C26 SOR_SNZ PF01680.17 KKF95578.1 - 8.6e-104 345.8 6.9 1.2e-103 345.3 6.9 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KKF95578.1 - 1.2e-07 31.3 10.4 6e-07 29.0 2.2 2.9 1 1 2 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KKF95578.1 - 0.00037 19.7 0.1 0.52 9.4 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KKF95578.1 - 0.00046 19.7 0.5 0.033 13.6 0.0 2.4 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 KKF95578.1 - 0.0012 18.1 1.2 0.14 11.4 0.0 2.9 1 1 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 KKF95578.1 - 0.0019 18.2 0.0 0.0047 17.0 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TMP-TENI PF02581.17 KKF95578.1 - 0.058 12.7 0.8 1.5 8.2 0.1 2.5 2 0 0 2 2 2 0 Thiamine monophosphate synthase Ribosomal_L29 PF00831.23 KKF95578.1 - 0.073 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal L29 protein IGPS PF00218.21 KKF95578.1 - 0.088 12.0 0.1 0.58 9.3 0.0 2.2 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.15 KKF95578.1 - 0.42 10.0 9.3 0.3 10.4 2.3 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase NB-ARC PF00931.22 KKF95579.1 - 5.8e-06 25.7 0.0 9.5e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Patatin PF01734.22 KKF95579.1 - 0.0041 17.3 0.0 0.48 10.6 0.0 2.5 1 1 1 2 2 2 1 Patatin-like phospholipase AAA_22 PF13401.6 KKF95579.1 - 0.0067 16.7 0.0 0.021 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF3088 PF11287.8 KKF95579.1 - 0.071 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) Prefoldin PF02996.17 KKF95579.1 - 0.15 12.0 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Prefoldin subunit WAC_Acf1_DNA_bd PF10537.9 KKF95580.1 - 1e-27 96.6 0.0 3.3e-27 94.9 0.0 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KKF95580.1 - 4.5e-17 62.4 0.0 4.5e-17 62.4 0.0 3.1 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KKF95580.1 - 1.4e-13 50.9 0.2 2.8e-13 49.9 0.2 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KKF95580.1 - 8.4e-08 31.6 0.0 2.4e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF5093 PF17011.5 KKF95580.1 - 3.8 7.8 5.9 0.63 10.3 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5093) Sigma70_ner PF04546.13 KKF95580.1 - 5.1 6.9 25.2 0.039 13.8 3.2 3.5 3 0 0 3 3 3 0 Sigma-70, non-essential region MMS1_N PF10433.9 KKF95581.1 - 4.5e-115 385.1 0.0 6.5e-115 384.5 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KKF95581.1 - 4e-94 315.5 0.0 6.2e-94 314.9 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region DUF2040 PF09745.9 KKF95581.1 - 1.4e-29 102.6 14.0 1.4e-29 102.6 14.0 3.4 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) KGG PF10685.9 KKF95581.1 - 2.1 8.7 7.6 9.5 6.6 0.9 3.2 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif zf-Tim10_DDP PF02953.15 KKF95582.1 - 4e-23 80.8 0.4 5.1e-23 80.5 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.8 KKF95582.1 - 0.18 12.3 0.1 0.22 12.0 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) Lectin_leg-like PF03388.13 KKF95583.1 - 3.3e-65 219.7 0.0 4e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KKF95583.1 - 0.00068 19.3 0.1 0.35 10.3 0.0 2.4 3 0 0 3 3 3 2 Legume lectin domain ATG27 PF09451.10 KKF95583.1 - 0.0095 15.8 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Serinc PF03348.15 KKF95583.1 - 0.023 13.6 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CPT PF07931.12 KKF95584.1 - 0.042 13.7 0.0 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Pkinase PF00069.25 KKF95585.1 - 9.3e-74 248.1 0.2 2.5e-73 246.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95585.1 - 6.2e-37 127.3 0.0 1.4e-36 126.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF95585.1 - 1.4e-08 34.4 0.0 2.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like CorA PF01544.18 KKF95586.1 - 9.7e-05 21.8 7.0 0.00073 18.9 7.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein RPA_interact_M PF14767.6 KKF95586.1 - 0.057 14.0 0.2 0.21 12.2 0.0 2.1 2 0 0 2 2 2 0 Replication protein A interacting middle DUF2207 PF09972.9 KKF95586.1 - 0.12 11.1 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OATP PF03137.20 KKF95586.1 - 0.16 10.3 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family LMBR1 PF04791.16 KKF95587.1 - 5e-93 312.7 0.7 6e-93 312.5 0.7 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF4164 PF13747.6 KKF95587.1 - 2.4 8.5 5.0 1.6 9.1 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Hat1_N PF10394.9 KKF95588.1 - 2.6e-27 96.0 0.0 5.1e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KKF95588.1 - 0.0083 16.3 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKF95588.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GAT PF03127.14 KKF95588.1 - 0.061 13.6 1.4 1.5 9.2 0.2 2.4 2 0 0 2 2 2 0 GAT domain Acetyltransf_7 PF13508.7 KKF95588.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain P5CR_dimer PF14748.6 KKF95589.1 - 2.5e-32 111.2 3.9 3.1e-32 110.9 2.4 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KKF95589.1 - 4.5e-09 36.8 3.6 1.2e-07 32.2 3.6 2.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.8 KKF95590.1 - 1.9e-35 121.5 1.5 1.9e-35 121.5 1.5 1.6 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KKF95590.1 - 1.7e-19 69.7 7.0 1.7e-19 69.7 7.0 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus GCIP PF13324.6 KKF95590.1 - 0.039 13.5 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Ribosomal_L12 PF00542.19 KKF95591.1 - 3.9e-20 71.9 6.7 2.1e-19 69.6 5.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KKF95591.1 - 4.6e-11 42.3 14.4 4.6e-11 42.3 14.4 3.6 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain DEC-1_N PF04625.13 KKF95591.1 - 0.01 14.9 1.3 0.01 14.9 1.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SpoVIF PF14069.6 KKF95591.1 - 0.11 12.3 0.7 0.25 11.2 0.7 1.7 1 1 0 1 1 1 0 Stage VI sporulation protein F AAA_5 PF07728.14 KKF95592.1 - 5e-126 415.3 0.1 8.4e-21 74.4 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KKF95592.1 - 3.4e-38 130.1 4.7 2.1e-12 47.2 0.0 5.9 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_3 PF07726.11 KKF95592.1 - 1.8e-32 111.9 0.0 3.4e-10 39.9 0.0 7.4 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KKF95592.1 - 1.1e-29 103.2 0.9 3e-05 23.6 0.0 7.0 6 1 0 6 6 6 6 P-loop containing dynein motor region AAA_lid_5 PF17865.1 KKF95592.1 - 2.4e-29 101.5 0.1 6e-28 97.0 0.0 2.8 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_16 PF13191.6 KKF95592.1 - 1.6e-28 100.3 28.3 1e-05 26.0 0.1 10.0 8 3 0 8 8 8 6 AAA ATPase domain AAA PF00004.29 KKF95592.1 - 1.9e-28 99.5 0.2 5.3e-05 23.6 0.0 7.5 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 KKF95592.1 - 2.6e-23 82.5 0.3 0.0025 16.9 0.1 8.7 8 1 0 8 8 8 4 Hydrolytic ATP binding site of dynein motor region Dynein_heavy PF03028.15 KKF95592.1 - 2.9e-23 82.2 0.0 0.00012 22.2 0.0 7.5 8 0 0 8 8 6 5 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 KKF95592.1 - 4.2e-20 72.6 0.1 0.016 15.8 0.0 7.1 6 0 0 6 6 6 4 AAA domain AAA_22 PF13401.6 KKF95592.1 - 4.6e-20 72.3 1.9 0.052 13.8 0.0 7.9 7 0 0 7 7 6 4 AAA domain AAA_33 PF13671.6 KKF95592.1 - 3.2e-19 69.5 0.2 0.0033 17.6 0.0 6.8 6 0 0 6 6 6 4 AAA domain Sigma54_activat PF00158.26 KKF95592.1 - 3.3e-17 62.7 0.2 0.073 12.8 0.0 6.5 6 0 0 6 6 6 4 Sigma-54 interaction domain TsaE PF02367.17 KKF95592.1 - 2.8e-16 59.6 6.2 0.052 13.5 0.0 6.4 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KKF95592.1 - 9.6e-16 58.1 2.4 0.0085 15.8 0.0 7.1 6 1 0 6 6 6 3 AAA domain AAA_14 PF13173.6 KKF95592.1 - 4.5e-15 55.8 0.0 0.0064 16.5 0.0 7.5 8 0 0 8 8 6 2 AAA domain ABC_tran PF00005.27 KKF95592.1 - 2.4e-14 54.0 6.7 0.0076 16.8 0.0 7.0 7 0 0 7 7 6 3 ABC transporter T2SSE PF00437.20 KKF95592.1 - 4.1e-13 49.0 3.1 0.0069 15.5 0.0 6.5 6 0 0 6 6 6 2 Type II/IV secretion system protein RNA_helicase PF00910.22 KKF95592.1 - 8.6e-13 48.6 0.5 0.18 12.2 0.0 6.6 6 0 0 6 6 6 1 RNA helicase RsgA_GTPase PF03193.16 KKF95592.1 - 1.1e-12 48.1 0.7 0.25 11.3 0.0 6.4 6 0 0 6 6 6 3 RsgA GTPase Rad17 PF03215.15 KKF95592.1 - 2.5e-12 47.1 0.3 0.047 13.6 0.0 6.5 6 0 0 6 6 6 2 Rad17 P-loop domain Mg_chelatase PF01078.21 KKF95592.1 - 3.7e-12 46.1 2.3 1.4 8.3 0.1 8.8 9 0 0 9 9 8 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KKF95592.1 - 5.6e-12 45.7 5.8 0.0048 16.7 0.0 6.9 8 0 0 8 8 5 3 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KKF95592.1 - 6.4e-12 45.2 3.3 0.018 14.3 0.0 6.9 6 0 0 6 6 6 2 Zeta toxin NACHT PF05729.12 KKF95592.1 - 1.7e-11 44.3 10.5 0.22 11.4 0.1 7.2 7 0 0 7 7 7 3 NACHT domain Sigma54_activ_2 PF14532.6 KKF95592.1 - 3.6e-11 43.3 0.3 0.0028 17.7 0.0 6.0 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_28 PF13521.6 KKF95592.1 - 5.5e-11 43.0 3.5 0.52 10.5 0.1 6.8 6 0 0 6 6 6 1 AAA domain IstB_IS21 PF01695.17 KKF95592.1 - 3.6e-10 39.9 0.2 0.54 10.0 0.0 6.4 6 0 0 6 6 6 1 IstB-like ATP binding protein AAA_29 PF13555.6 KKF95592.1 - 5.4e-10 38.9 0.6 0.19 11.5 0.1 6.5 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KKF95592.1 - 2.8e-09 36.8 0.8 0.2 11.2 0.0 5.7 5 0 0 5 5 5 2 AAA domain DUF815 PF05673.13 KKF95592.1 - 7.8e-09 35.1 1.0 2.2 7.4 0.0 5.7 6 0 0 6 6 5 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KKF95592.1 - 2.5e-08 34.4 5.2 2 8.7 0.1 7.0 7 0 0 7 7 5 1 AAA domain TIP49 PF06068.13 KKF95592.1 - 1.3e-07 31.2 1.8 2.8 7.0 0.0 5.6 6 0 0 6 6 6 1 TIP49 P-loop domain PduV-EutP PF10662.9 KKF95592.1 - 2.4e-07 30.6 1.2 0.061 13.1 0.0 5.3 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KKF95592.1 - 6.5e-07 29.5 0.0 5.7 6.8 0.0 5.9 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea TniB PF05621.11 KKF95592.1 - 1.5e-06 27.7 0.1 5.1 6.5 0.0 6.1 6 0 0 6 6 6 0 Bacterial TniB protein SRP54 PF00448.22 KKF95592.1 - 5.6e-06 26.1 4.1 2.3 7.8 0.0 5.6 6 0 0 6 6 5 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KKF95592.1 - 8.9e-06 25.6 0.3 11 5.6 0.0 6.2 6 0 0 6 6 6 0 AAA domain NTPase_1 PF03266.15 KKF95592.1 - 1e-05 25.5 7.6 2.4 8.0 0.1 6.0 6 0 0 6 6 5 1 NTPase MMR_HSR1 PF01926.23 KKF95592.1 - 1.5e-05 25.0 0.3 28 4.8 0.0 6.1 6 0 0 6 6 6 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KKF95592.1 - 1.7e-05 24.7 0.0 3.4 7.3 0.0 4.8 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase Roc PF08477.13 KKF95592.1 - 6.3e-05 23.2 2.2 7.3 6.8 0.1 5.8 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 KKF95592.1 - 8.7e-05 22.6 0.2 1.8 8.6 0.0 3.8 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.6 KKF95592.1 - 9.8e-05 22.9 19.4 4.8 7.6 0.0 7.6 7 0 0 7 7 5 0 AAA domain ResIII PF04851.15 KKF95592.1 - 0.00027 21.0 0.0 5 7.1 0.0 5.3 6 0 0 6 6 6 0 Type III restriction enzyme, res subunit AAA_9 PF12781.7 KKF95592.1 - 0.00084 18.5 0.0 0.11 11.6 0.0 3.9 4 0 0 4 4 4 1 ATP-binding dynein motor region cobW PF02492.19 KKF95592.1 - 0.0034 17.0 8.3 17 4.9 0.0 5.6 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 KKF95592.1 - 0.0038 17.1 5.0 5.5 6.8 0.0 5.2 6 0 0 6 6 5 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 KKF95592.1 - 0.0044 16.9 6.3 11 5.7 0.1 5.5 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein DnaB_C PF03796.15 KKF95592.1 - 0.0049 16.2 1.6 8 5.7 0.0 4.1 4 0 0 4 4 3 0 DnaB-like helicase C terminal domain PhoH PF02562.16 KKF95592.1 - 0.0054 16.2 2.2 6.8 6.1 0.0 4.7 6 0 0 6 6 4 0 PhoH-like protein NB-ARC PF00931.22 KKF95592.1 - 0.01 15.0 5.1 4.4 6.4 0.0 4.8 5 0 0 5 5 5 0 NB-ARC domain DAP3 PF10236.9 KKF95592.1 - 0.011 15.0 2.8 9.5 5.3 0.0 4.4 4 0 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 GAF_2 PF13185.6 KKF95592.1 - 0.017 15.4 0.3 0.97 9.7 0.0 3.9 4 0 0 4 4 2 0 GAF domain ATPase PF06745.13 KKF95592.1 - 0.02 14.3 1.3 27 4.0 0.0 4.8 5 0 0 5 5 5 0 KaiC PRK PF00485.18 KKF95592.1 - 0.031 14.0 0.3 10 5.8 0.0 3.9 5 0 0 5 5 3 0 Phosphoribulokinase / Uridine kinase family Thymidylate_kin PF02223.17 KKF95592.1 - 0.035 13.8 0.4 6.2 6.4 0.0 3.8 4 0 0 4 4 3 0 Thymidylate kinase VWA PF00092.28 KKF95592.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain KTI12 PF08433.10 KKF95592.1 - 0.14 11.6 0.0 29 4.0 0.0 3.3 3 0 0 3 3 2 0 Chromatin associated protein KTI12 CPT PF07931.12 KKF95592.1 - 0.15 11.9 4.9 28 4.5 0.0 5.6 6 1 0 6 6 3 0 Chloramphenicol phosphotransferase-like protein Guanylate_kin PF00625.21 KKF95592.1 - 0.66 9.6 2.6 18 5.0 0.1 3.8 5 0 0 5 5 4 0 Guanylate kinase Cytidylate_kin PF02224.18 KKF95592.1 - 2.6 7.7 6.7 55 3.4 0.2 4.8 5 0 0 5 5 5 0 Cytidylate kinase Pyr_redox_2 PF07992.14 KKF95593.1 - 1.3e-43 149.4 0.0 1.1e-42 146.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKF95593.1 - 1.9e-10 41.1 0.0 1.8e-07 31.6 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKF95593.1 - 7.6e-05 22.0 0.1 0.0082 15.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KKF95593.1 - 0.024 14.9 0.1 15 5.9 0.0 3.1 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain EspB_PE PF18625.1 KKF95593.1 - 0.061 13.8 0.6 0.16 12.5 0.6 1.7 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain Pyr_redox_3 PF13738.6 KKF95593.1 - 0.14 11.3 0.0 0.87 8.8 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KKF95593.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DPBB_1 PF03330.18 KKF95594.1 - 5.1e-07 29.9 0.0 1.9e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KKF95594.1 - 0.001 18.9 0.5 0.0038 17.1 0.1 2.1 3 0 0 3 3 3 1 Barwin family Pollen_allerg_1 PF01357.21 KKF95594.1 - 0.0015 18.5 0.4 0.003 17.5 0.4 1.4 1 0 0 1 1 1 1 Pollen allergen Cerato-platanin PF07249.12 KKF95594.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Cerato-platanin HeLo PF14479.6 KKF95595.1 - 4.4e-07 29.9 0.3 0.0035 17.2 0.1 2.5 1 1 0 2 2 2 2 Prion-inhibition and propagation His_biosynth PF00977.21 KKF95596.1 - 2e-35 122.3 0.0 2.5e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KKF95596.1 - 0.069 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.17 KKF95596.1 - 0.17 11.2 0.1 2.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase Anillin PF08174.11 KKF95597.1 - 3.2e-12 47.1 0.0 7.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KKF95597.1 - 9.1e-10 39.0 0.0 3e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 KKF95597.1 - 0.039 14.4 0.0 0.19 12.2 0.0 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain DUF1899 PF08953.11 KKF95598.1 - 4.5e-35 119.3 0.4 9.2e-35 118.3 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KKF95598.1 - 2.4e-18 65.7 0.1 5.1e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KKF95598.1 - 1e-13 51.5 9.0 0.0002 22.1 0.5 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF95598.1 - 2.7e-06 27.6 0.6 0.021 15.1 0.2 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TRAPPC10 PF12584.8 KKF95599.1 - 1.9e-17 63.4 0.0 3.5e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 KKF95599.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 IF-2B PF01008.17 KKF95600.1 - 8.5e-73 245.0 1.0 1e-72 244.7 1.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_M20 PF01546.28 KKF95601.1 - 3.3e-19 69.4 1.3 1.2e-13 51.3 0.3 2.2 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKF95601.1 - 2.4e-17 62.8 0.0 3.9e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2205 PF10224.9 KKF95603.1 - 9.3e-18 64.0 5.0 1.3e-17 63.6 5.0 1.2 1 0 0 1 1 1 1 Short coiled-coil protein SNF2_N PF00176.23 KKF95604.1 - 6.3e-46 156.7 0.0 8.1e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKF95604.1 - 5.7e-19 68.5 0.1 1.6e-18 67.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KKF95604.1 - 0.0047 16.1 0.1 0.92 8.6 0.0 2.6 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KKF95604.1 - 0.0051 16.8 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 KKF95604.1 - 0.013 15.8 6.1 0.013 15.8 6.1 3.0 1 1 2 3 3 3 0 HSA NDUF_B8 PF05821.11 KKF95605.1 - 6.6e-09 35.9 0.1 9e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) AA_permease_2 PF13520.6 KKF95607.1 - 3.6e-55 187.5 51.0 4.1e-55 187.3 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKF95607.1 - 5.7e-24 84.5 42.8 7.6e-24 84.1 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease Pho88 PF10032.9 KKF95607.1 - 0.15 11.4 0.4 0.33 10.2 0.4 1.5 1 0 0 1 1 1 0 Phosphate transport (Pho88) 2-Hacid_dh_C PF02826.19 KKF95608.1 - 2.6e-33 114.9 0.0 4.5e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKF95608.1 - 7.1e-18 64.6 0.0 8.7e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KKF95608.1 - 0.062 13.9 0.9 0.77 10.4 0.2 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans_2 PF11951.8 KKF95609.1 - 7.3e-45 153.4 0.3 1e-44 153.0 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldolase_II PF00596.21 KKF95610.1 - 1.7e-45 155.2 0.0 2.2e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Esterase_phd PF10503.9 KKF95611.1 - 6.1e-22 78.2 3.0 8.5e-22 77.7 3.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KKF95611.1 - 6.6e-11 42.1 0.5 1.1e-10 41.3 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KKF95611.1 - 0.001 18.9 0.0 0.011 15.6 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KKF95611.1 - 0.003 17.3 2.7 0.0035 17.0 2.0 1.4 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KKF95611.1 - 0.051 13.2 4.0 0.03 14.0 0.7 2.0 1 1 0 2 2 2 0 alpha/beta hydrolase fold Eno-Rase_NADH_b PF12242.8 KKF95611.1 - 0.11 12.3 0.0 0.39 10.5 0.0 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LIP PF03583.14 KKF95611.1 - 0.28 10.5 5.8 2.2 7.5 1.3 2.6 2 1 1 3 3 3 0 Secretory lipase Toxin_10 PF05431.11 KKF95612.1 - 0.0089 15.5 1.3 0.015 14.8 1.3 1.3 1 0 0 1 1 1 1 Insecticidal Crystal Toxin, P42 PWWP PF00855.17 KKF95614.1 - 8.9e-17 61.3 1.1 1e-15 57.9 0.0 3.1 3 0 0 3 3 3 1 PWWP domain Med26 PF08711.11 KKF95614.1 - 0.0094 16.0 0.4 0.019 15.0 0.4 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain ORC3_N PF07034.11 KKF95615.1 - 2.1e-37 129.0 0.1 2e-36 125.8 0.1 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KKF95615.1 - 8.1e-25 87.5 0.0 1.6e-15 57.4 0.0 2.5 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal Sec66 PF09802.9 KKF95616.1 - 8.1e-75 250.3 1.2 9.3e-75 250.2 1.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 CDPS PF16715.5 KKF95616.1 - 0.28 10.8 3.5 0.34 10.5 3.5 1.1 1 0 0 1 1 1 0 Cyclodipeptide synthase CPSase_L_D2 PF02786.17 KKF95617.1 - 1.9e-111 370.6 0.0 2.7e-84 281.9 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KKF95617.1 - 4.9e-41 139.9 0.0 1.4e-40 138.4 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KKF95617.1 - 7.6e-21 74.4 0.0 5.1e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KKF95617.1 - 3.8e-18 65.8 0.2 8.6e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KKF95617.1 - 5.2e-12 45.6 0.0 3.9e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 KKF95617.1 - 6.1e-06 26.1 0.1 0.058 13.2 0.0 2.9 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KKF95617.1 - 2e-05 24.3 0.0 0.023 14.3 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KKF95617.1 - 4e-05 23.2 0.0 0.17 11.3 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 KKF95617.1 - 0.00047 19.8 0.0 0.006 16.2 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain NPL4 PF05021.15 KKF95618.1 - 2.6e-124 414.6 0.0 4.1e-124 413.9 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KKF95618.1 - 1.2e-62 210.3 0.0 1.8e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KKF95618.1 - 0.00025 21.4 0.0 0.0008 19.8 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 tRNA-synt_2d PF01409.20 KKF95619.1 - 1.4e-84 283.4 0.0 1.9e-84 283.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KKF95619.1 - 7.3e-17 61.4 0.6 1.8e-16 60.2 0.6 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KKF95619.1 - 2.5e-06 27.1 0.0 0.0025 17.3 0.0 2.6 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KKF95619.1 - 1.8e-05 24.0 0.1 0.00067 18.8 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KKF95619.1 - 0.00052 20.0 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 KKF95619.1 - 0.0011 18.9 0.6 0.0035 17.3 0.6 2.0 1 0 0 1 1 1 1 PheRS DNA binding domain 2 RTC PF01137.21 KKF95620.1 - 1.2e-29 103.1 0.1 1.4e-29 102.9 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KKF95620.1 - 7.6e-29 100.3 0.0 1.4e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PPR_2 PF13041.6 KKF95621.1 - 8.1e-07 29.1 3.7 0.017 15.3 0.1 5.2 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.20 KKF95621.1 - 0.0043 17.2 6.1 3.6 8.1 0.1 5.3 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.6 KKF95621.1 - 0.046 13.8 0.0 86 3.3 0.0 3.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Bromo_TP PF07524.13 KKF95622.1 - 7e-08 32.4 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 KKF95622.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Aldedh PF00171.22 KKF95623.1 - 1.9e-131 438.8 0.2 2.2e-131 438.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.19 KKF95624.1 - 1e-53 182.9 0.3 3.9e-51 174.4 0.0 2.3 3 0 0 3 3 3 2 FAD binding domain Phe_hydrox_dim PF07976.12 KKF95624.1 - 2.1e-28 99.4 0.0 3.9e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 KKF95624.1 - 0.042 12.9 0.0 0.091 11.8 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase Indigoidine_A PF04227.12 KKF95625.1 - 2.9e-86 289.4 0.2 4e-86 289.0 0.2 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KKF95625.1 - 3.6e-11 42.9 0.0 1.1e-08 34.8 0.0 3.1 3 1 0 3 3 3 2 pfkB family carbohydrate kinase SLD5_C PF16922.5 KKF95626.1 - 2.1e-11 43.8 0.0 3.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus WD40 PF00400.32 KKF95627.1 - 2e-07 31.6 0.3 0.34 11.9 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.12 KKF95627.1 - 4.1e-06 26.6 0.1 0.0015 18.4 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KKF95627.1 - 0.00019 21.7 0.0 0.038 14.3 0.0 3.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Pro_isomerase PF00160.21 KKF95628.1 - 2e-49 167.9 0.2 8.8e-49 165.8 0.1 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KKF95628.1 - 1.9e-09 38.0 0.0 5.6e-05 23.8 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF95628.1 - 0.0013 19.0 0.0 0.27 11.6 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain MCM PF00493.23 KKF95629.1 - 2e-100 334.5 0.0 3.1e-100 333.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain ADK PF00406.22 KKF95629.1 - 1.2e-43 148.8 0.1 3.2e-43 147.4 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase MCM_OB PF17207.3 KKF95629.1 - 1.5e-39 134.7 2.2 1.9e-39 134.4 1.2 1.7 2 0 0 2 2 1 1 MCM OB domain AAA_17 PF13207.6 KKF95629.1 - 9.2e-36 123.3 0.0 4.2e-35 121.1 0.0 2.3 1 0 0 1 1 1 1 AAA domain MCM_lid PF17855.1 KKF95629.1 - 1e-27 96.3 3.2 2.5e-27 95.1 3.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKF95629.1 - 1.5e-13 51.2 0.1 5.8e-13 49.3 0.1 2.1 1 0 0 1 1 1 1 MCM N-terminal domain AAA_18 PF13238.6 KKF95629.1 - 9.1e-07 29.5 0.0 2.8e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KKF95629.1 - 6.7e-06 26.1 0.1 0.0028 17.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKF95629.1 - 0.0002 21.6 0.0 0.0016 18.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KKF95629.1 - 0.0002 20.8 0.4 0.002 17.5 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KKF95629.1 - 0.012 15.4 0.0 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 KKF95629.1 - 0.03 14.0 0.8 1.2 8.7 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase PAS_7 PF12860.7 KKF95629.1 - 0.069 13.3 0.0 0.49 10.6 0.0 2.6 1 0 0 1 1 1 0 PAS fold Ribosomal_60s PF00428.19 KKF95629.1 - 1.1 9.8 17.5 6.2 7.5 1.4 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein CbtA PF09490.10 KKF95629.1 - 1.4 8.6 7.9 2.9 7.6 7.9 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) LXG PF04740.12 KKF95629.1 - 2.7 7.6 4.8 14 5.4 0.1 2.8 2 1 1 3 3 3 0 LXG domain of WXG superfamily Peptidase_M13 PF01431.21 KKF95630.1 - 5.3e-43 147.0 1.1 6.6e-43 146.7 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 KKF95630.1 - 1.9e-38 133.2 0.2 2.9e-31 109.5 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M13 Vma12 PF11712.8 KKF95631.1 - 1.1e-43 148.6 0.0 1.8e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1772 PF08592.11 KKF95631.1 - 0.0023 18.2 0.2 0.0049 17.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2681 PF10883.8 KKF95631.1 - 0.21 12.0 0.2 0.21 12.0 0.2 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2681) PsbN PF02468.15 KKF95631.1 - 4.5 7.2 6.0 0.67 9.9 0.8 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) polyprenyl_synt PF00348.17 KKF95632.1 - 5.8e-75 251.7 0.0 9e-75 251.0 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3659 PF12396.8 KKF95632.1 - 0.15 12.0 0.0 4 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Amidohydro_1 PF01979.20 KKF95633.1 - 8.2e-25 87.8 0.0 6.7e-24 84.8 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKF95633.1 - 3.6e-10 39.9 0.4 9.3e-06 25.4 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family ABC2_membrane PF01061.24 KKF95634.1 - 6.5e-22 78.0 12.8 1e-21 77.4 12.8 1.1 1 0 0 1 1 1 1 ABC-2 type transporter Myb_DNA-binding PF00249.31 KKF95635.1 - 3.5e-09 36.7 0.0 3.9e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKF95635.1 - 4e-07 30.2 1.2 0.00015 21.9 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain WD40 PF00400.32 KKF95636.1 - 8.2e-11 42.3 4.5 0.0032 18.3 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF95636.1 - 0.00063 20.0 0.4 26 5.2 0.0 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Gln_amidase PF15644.6 KKF95636.1 - 0.061 14.3 0.3 5.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase UPF0086 PF01868.16 KKF95637.1 - 1.5e-30 105.0 0.6 2.3e-30 104.3 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Acyltransferase PF01553.21 KKF95638.1 - 1.1e-16 60.6 0.0 2.2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase T2SSI PF02501.17 KKF95638.1 - 0.13 12.5 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I Pantoate_ligase PF02569.15 KKF95639.1 - 4.6e-93 311.3 0.0 5.6e-93 311.0 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase FAD_binding_2 PF00890.24 KKF95640.1 - 1e-91 308.1 0.0 1.2e-91 307.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKF95640.1 - 7.1e-06 26.2 0.4 2.7e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KKF95640.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKF95640.1 - 0.00012 21.8 0.0 0.00056 19.6 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKF95640.1 - 0.0023 17.2 0.7 0.0048 16.2 0.2 1.7 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KKF95640.1 - 0.0042 16.2 0.2 0.0042 16.2 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KKF95640.1 - 0.0063 15.8 0.4 0.042 13.1 0.2 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKF95640.1 - 0.017 14.5 0.1 0.035 13.4 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KKF95640.1 - 0.073 11.8 5.7 0.077 11.7 0.2 2.4 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 KKF95640.1 - 0.36 10.0 0.7 0.58 9.4 0.7 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OPT PF03169.15 KKF95641.1 - 2.4e-187 624.4 51.1 2.7e-187 624.2 51.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EIAV_GP90 PF00971.18 KKF95641.1 - 0.52 8.9 1.9 7.2 5.2 0.1 2.2 2 0 0 2 2 2 0 EIAV coat protein, gp90 Mito_carr PF00153.27 KKF95642.1 - 3.1e-68 225.8 0.9 2.5e-22 78.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LSM PF01423.22 KKF95643.1 - 2.9e-19 68.5 0.1 3.8e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 KKF95643.1 - 0.035 14.6 12.0 0.06 13.9 12.0 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RhlB PF12300.8 KKF95643.1 - 8.1 6.6 11.7 11 6.1 11.7 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB UBA_4 PF14555.6 KKF95644.1 - 2.6e-12 46.4 0.0 6.1e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KKF95644.1 - 4.8e-09 36.3 0.0 9.4e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain rRNA_processing PF08524.11 KKF95644.1 - 1.3 9.1 10.0 2 8.4 10.0 1.2 1 0 0 1 1 1 0 rRNA processing GAT PF03127.14 KKF95645.1 - 4.7e-13 49.2 0.2 1.2e-12 48.0 0.2 1.7 1 0 0 1 1 1 1 GAT domain DDA1 PF10172.9 KKF95645.1 - 0.077 13.3 1.0 7.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Det1 complexing ubiquitin ligase Aminotran_3 PF00202.21 KKF95646.1 - 2.9e-29 102.0 0.2 3.7e-20 72.0 0.0 2.9 2 1 0 2 2 2 2 Aminotransferase class-III Methyltransf_11 PF08241.12 KKF95646.1 - 2e-07 31.6 0.0 5.3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF95646.1 - 1.2e-05 25.9 0.0 4.5e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF95646.1 - 0.00028 20.7 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF95646.1 - 0.00048 20.0 0.0 0.00085 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF95646.1 - 0.0015 19.2 0.0 0.0036 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKF95646.1 - 0.0042 16.5 0.0 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Zn_clus PF00172.18 KKF95647.1 - 0.0038 17.3 0.4 0.0066 16.6 0.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_1 PF00300.22 KKF95648.1 - 2.5e-35 122.0 1.6 6.1e-17 62.0 0.2 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) EF-hand_1 PF00036.32 KKF95649.1 - 9.1e-19 65.6 11.9 1.7e-07 30.3 1.4 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KKF95649.1 - 7.6e-15 55.1 4.2 3.7e-09 36.9 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KKF95649.1 - 7.9e-15 53.5 11.9 5.5e-06 25.9 3.6 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KKF95649.1 - 6.3e-12 44.4 11.8 3.5e-05 23.1 0.7 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KKF95649.1 - 1.4e-11 44.1 10.9 3.1e-07 30.1 0.6 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KKF95649.1 - 9.4e-08 32.0 1.1 0.0011 18.8 0.1 2.7 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KKF95649.1 - 4e-05 23.6 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 2 Caleosin related protein SPARC_Ca_bdg PF10591.9 KKF95649.1 - 0.00027 21.2 0.2 0.25 11.6 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KKF95649.1 - 0.0072 16.6 0.3 0.04 14.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 KKF95649.1 - 0.022 15.0 2.0 0.054 13.7 2.0 1.7 1 1 0 1 1 1 0 Dockerin type I domain DUF4834 PF16118.5 KKF95649.1 - 0.031 15.2 1.4 0.063 14.2 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF305 PF03713.13 KKF95649.1 - 0.12 12.5 2.7 9.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF305) dsDNA_bind PF01984.20 KKF95650.1 - 2.8e-35 121.0 16.7 3.1e-35 120.8 16.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain LCIB_C_CA PF18599.1 KKF95650.1 - 0.6 9.4 5.4 1.2 8.4 5.4 1.4 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases EF-1_beta_acid PF10587.9 KKF95650.1 - 2 8.9 7.1 0.61 10.6 2.7 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region AAA PF00004.29 KKF95651.1 - 8.4e-50 168.6 0.0 3.6e-41 140.7 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKF95651.1 - 3.4e-10 40.6 0.2 0.00083 19.8 0.3 3.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 KKF95651.1 - 5.7e-09 35.6 0.1 2.2e-08 33.8 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KKF95651.1 - 1.7e-07 31.1 0.0 1.1e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KKF95651.1 - 2.9e-06 27.5 0.0 6.7e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKF95651.1 - 7.2e-06 26.3 1.3 0.086 13.1 0.2 4.3 4 1 0 4 4 2 1 AAA domain Sigma54_activ_2 PF14532.6 KKF95651.1 - 0.00011 22.3 0.0 0.69 10.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 KKF95651.1 - 0.00034 20.6 0.1 0.019 15.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KKF95651.1 - 0.00068 19.6 0.2 0.8 9.6 0.0 2.9 2 1 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 KKF95651.1 - 0.00077 19.6 0.4 0.071 13.3 0.0 3.9 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 KKF95651.1 - 0.0012 19.2 0.0 0.023 15.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Bac_DnaA PF00308.18 KKF95651.1 - 0.0024 17.7 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein Sigma54_activat PF00158.26 KKF95651.1 - 0.004 16.9 0.0 1.9 8.2 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 KKF95651.1 - 0.0046 17.0 0.0 3.1 7.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KKF95651.1 - 0.0074 16.8 0.2 0.11 13.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 KKF95651.1 - 0.0094 15.2 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KKF95651.1 - 0.014 14.8 0.0 0.12 11.7 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KKF95651.1 - 0.016 14.7 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 KKF95651.1 - 0.028 14.2 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KKF95651.1 - 0.032 14.8 0.0 0.21 12.1 0.0 2.5 2 0 0 2 2 1 0 ABC transporter AAA_30 PF13604.6 KKF95651.1 - 0.037 13.8 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 KKF95651.1 - 0.042 13.9 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKF95651.1 - 0.095 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 KKF95651.1 - 0.13 11.2 0.1 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Torsin PF06309.11 KKF95651.1 - 0.15 12.1 0.1 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Torsin Parvo_NS1 PF01057.17 KKF95651.1 - 0.19 10.8 0.0 0.68 9.0 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KKF95651.1 - 0.64 9.8 0.0 0.64 9.8 0.0 3.9 5 0 0 5 5 4 0 AAA domain BCNT PF07572.12 KKF95652.1 - 1.7e-22 79.2 2.6 3.5e-22 78.2 2.6 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development MA3 PF02847.17 KKF95653.1 - 8.3e-22 77.3 0.0 1.8e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KKF95653.1 - 1.3e-12 47.8 2.2 1.4e-12 47.7 0.5 1.9 2 0 0 2 2 2 1 MIF4G domain LsmAD PF06741.13 KKF95653.1 - 1.1 9.9 5.4 0.86 10.2 3.3 1.9 1 1 1 2 2 2 0 LsmAD domain Dus PF01207.17 KKF95654.1 - 5.1e-59 199.9 0.0 8.6e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KKF95654.1 - 0.0048 16.1 0.0 0.0084 15.3 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DUF908 PF06012.12 KKF95654.1 - 0.028 13.8 0.1 5.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) MFS_1 PF07690.16 KKF95656.1 - 3.2e-15 55.9 3.6 4e-15 55.6 3.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Carb_anhydrase PF00194.21 KKF95657.1 - 5.2e-32 111.4 0.0 9.7e-32 110.5 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase PapA_C PF16911.5 KKF95657.1 - 0.094 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus DUF4078 PF13300.6 KKF95658.1 - 1.4e-31 108.6 11.7 1.4e-31 108.6 11.7 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) Cwf_Cwc_15 PF04889.12 KKF95658.1 - 0.66 9.7 31.1 1.3 8.6 6.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3323 PF11796.8 KKF95658.1 - 5 7.0 13.8 0.025 14.5 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Atg14 PF10186.9 KKF95658.1 - 5.9 5.9 19.0 0.11 11.6 7.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KKF95658.1 - 6.6 6.8 18.8 0.1 12.7 2.5 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Homoserine_dh PF00742.19 KKF95659.1 - 4.4e-52 176.5 0.0 6.2e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KKF95659.1 - 6.7e-19 68.7 0.0 5.5e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain IGPS PF00218.21 KKF95659.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase PXA PF02194.15 KKF95660.1 - 9.8e-30 103.9 0.1 3e-29 102.3 0.1 1.8 1 0 0 1 1 1 1 PXA domain PX PF00787.24 KKF95660.1 - 1.7e-20 73.1 0.5 3.7e-20 72.0 0.5 1.6 1 0 0 1 1 1 1 PX domain RRM_1 PF00076.22 KKF95660.1 - 1.3e-10 41.0 0.1 3.9e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEX11 PF05648.14 KKF95661.1 - 8.8e-27 94.0 0.8 2e-14 53.6 0.2 2.0 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) IL34 PF15036.6 KKF95661.1 - 0.046 13.8 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 FBPase PF00316.20 KKF95662.1 - 1.4e-67 226.9 0.9 1.7e-67 226.6 0.9 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KKF95662.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family ENTH PF01417.20 KKF95663.1 - 2.7e-45 153.4 0.0 4e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KKF95663.1 - 6.3e-05 23.3 44.7 0.00014 22.2 20.9 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1720) UIM PF02809.20 KKF95663.1 - 0.0028 17.5 1.7 0.0028 17.5 1.7 3.0 2 1 0 2 2 2 1 Ubiquitin interaction motif ANTH PF07651.16 KKF95663.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 ANTH domain VHS PF00790.19 KKF95663.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 VHS domain Ribosomal_L7Ae PF01248.26 KKF95665.1 - 1.3e-21 76.2 0.8 2.4e-21 75.3 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 KKF95665.1 - 0.062 12.3 0.2 0.081 11.9 0.2 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) NTF2 PF02136.20 KKF95666.1 - 2.3e-30 105.6 0.6 2.6e-30 105.5 0.6 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Afi1 PF07792.12 KKF95667.1 - 1.2 9.6 4.6 9.5 6.7 0.4 2.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking 2OG-FeII_Oxy_3 PF13640.6 KKF95669.1 - 6.2e-09 36.6 0.0 1.2e-08 35.7 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.8 KKF95670.1 - 0.0069 15.2 1.5 0.008 15.0 0.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain GM_CSF PF01109.17 KKF95671.1 - 0.13 12.4 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor RRM_1 PF00076.22 KKF95672.1 - 1.1e-16 60.4 0.0 1.6e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.9 KKF95673.1 - 2.2e-44 150.0 1.1 2.5e-44 149.9 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 HrpB2 PF09487.10 KKF95673.1 - 0.063 13.7 0.2 0.082 13.3 0.2 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Sedlin_N PF04628.13 KKF95674.1 - 9.6e-43 145.4 0.0 1.1e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KKF95674.1 - 0.00044 20.2 0.1 0.0037 17.2 0.1 2.0 1 1 1 2 2 2 1 Sybindin-like family DUF5481 PF17578.2 KKF95674.1 - 0.057 13.8 0.1 0.098 13.1 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5481) CENP-T_C PF15511.6 KKF95675.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KKF95675.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KKF95675.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KKF95675.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KKF95675.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KKF95675.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KKF95675.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KKF95675.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KKF95675.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region TPR_1 PF00515.28 KKF95676.1 - 9.5e-36 120.2 26.6 5.5e-08 32.3 0.0 9.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 KKF95676.1 - 2.5e-32 108.3 30.6 6.6e-06 25.8 0.0 10.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 KKF95676.1 - 3.4e-25 86.1 22.5 0.002 18.2 0.0 10.0 12 0 0 12 12 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 KKF95676.1 - 6.7e-22 76.9 14.4 6.2e-07 29.0 1.0 9.2 7 3 4 11 11 10 3 TPR repeat TPR_17 PF13431.6 KKF95676.1 - 8.6e-20 69.6 14.4 0.056 13.8 0.0 9.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 KKF95676.1 - 2.7e-19 69.2 8.6 0.002 18.4 2.0 6.9 4 3 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KKF95676.1 - 2.6e-18 66.4 14.8 4.9e-09 36.7 0.2 5.7 4 2 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF95676.1 - 9.1e-18 64.3 21.3 3.3e-10 40.1 1.0 6.1 4 2 3 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KKF95676.1 - 1.2e-17 64.2 10.8 2.4e-06 27.9 0.8 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKF95676.1 - 8.1e-16 57.4 13.0 0.024 15.4 0.0 8.7 3 2 6 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 KKF95676.1 - 3e-12 45.7 16.5 0.004 17.1 0.0 7.9 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 KKF95676.1 - 9.5e-12 44.8 12.2 0.27 12.0 0.0 8.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKF95676.1 - 1.4e-10 41.2 1.9 0.024 14.8 0.1 5.7 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KKF95676.1 - 2.3e-08 33.6 5.2 0.0015 17.8 2.1 3.9 2 2 0 3 3 3 2 Tetratricopeptide repeat Sel1 PF08238.12 KKF95676.1 - 0.00089 19.9 6.3 12 6.7 0.0 5.5 6 0 0 6 6 5 0 Sel1 repeat DUF2225 PF09986.9 KKF95676.1 - 0.0012 18.6 5.6 0.067 12.9 3.5 3.4 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 KKF95676.1 - 0.029 14.4 10.9 0.24 11.5 0.2 4.7 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 KKF95676.1 - 0.57 11.0 3.2 36 5.4 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKF95676.1 - 0.71 10.0 3.4 4.7 7.4 0.1 3.5 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KKF95676.1 - 9.7 6.2 14.4 31 4.6 0.7 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TMEM208_SND2 PF05620.11 KKF95677.1 - 3.3e-47 160.4 0.2 3.7e-47 160.2 0.2 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 PI3_PI4_kinase PF00454.27 KKF95678.1 - 1.3e-32 113.6 0.0 2.1e-31 109.7 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 KKF95678.1 - 0.0082 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) AA_permease_2 PF13520.6 KKF95679.1 - 6.6e-66 222.9 23.5 1.5e-54 185.5 10.4 2.2 2 1 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KKF95679.1 - 3.5e-16 58.9 17.1 2.5e-15 56.1 6.7 2.2 2 0 0 2 2 2 2 Amino acid permease DUF4383 PF14325.6 KKF95679.1 - 0.034 14.4 2.4 0.19 12.0 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) CBFD_NFYB_HMF PF00808.23 KKF95681.1 - 1.1e-13 51.2 1.8 1.8e-13 50.5 1.8 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKF95681.1 - 0.001 19.4 0.3 0.001 19.4 0.3 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF2630 PF10944.8 KKF95681.1 - 0.0061 17.0 0.5 0.016 15.7 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2630) TAFII28 PF04719.14 KKF95681.1 - 0.052 13.6 0.8 0.089 12.9 0.8 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region RBR PF17208.3 KKF95681.1 - 0.91 10.3 8.4 0.75 10.6 4.3 2.5 3 0 0 3 3 3 0 RNA binding Region PUF PF00806.19 KKF95682.1 - 1.2e-21 75.1 0.0 0.00011 21.7 0.0 5.6 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KKF95682.1 - 8.6e-11 41.5 0.1 1.9e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF982 PF06169.12 KKF95682.1 - 0.2 11.7 1.1 0.54 10.3 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF982) PHD PF00628.29 KKF95683.1 - 3.6e-05 23.6 2.9 6.6e-05 22.7 2.9 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KKF95683.1 - 0.089 12.7 0.9 0.17 11.8 0.9 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KKF95683.1 - 0.41 10.6 3.6 0.84 9.6 3.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KKF95683.1 - 0.41 10.2 2.6 0.34 10.5 0.5 1.9 2 0 0 2 2 2 0 PHD-finger RuBisCO_large_N PF02788.16 KKF95683.1 - 0.46 10.7 2.0 1.1 9.4 2.0 1.7 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain Peptidase_M24 PF00557.24 KKF95684.1 - 5.2e-08 32.8 0.0 8.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3113 PF11310.8 KKF95684.1 - 0.065 13.2 0.2 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) SNF5 PF04855.12 KKF95685.1 - 4.7e-65 219.7 0.2 7.2e-64 215.8 0.2 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 XLF PF09302.11 KKF95685.1 - 0.023 14.9 0.0 0.17 12.0 0.0 2.0 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component HEAT_2 PF13646.6 KKF95686.1 - 0.0013 19.1 2.7 0.091 13.2 0.0 4.9 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KKF95686.1 - 0.0023 18.1 5.8 10 6.7 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Gcn1_N PF12074.8 KKF95686.1 - 0.087 12.1 0.1 1.1 8.4 0.0 2.8 4 0 0 4 4 4 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal mRNA_cap_enzyme PF01331.19 KKF95687.1 - 9.8e-52 175.6 0.1 1.4e-51 175.1 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 KKF95687.1 - 5.9e-06 26.1 0.0 0.00045 19.9 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain PX PF00787.24 KKF95688.1 - 6.2e-16 58.4 0.0 1.7e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KKF95688.1 - 2.5e-11 43.6 13.2 1.1e-06 28.4 0.9 2.1 2 0 0 2 2 2 2 Vps5 C terminal like TPR_10 PF13374.6 KKF95688.1 - 0.17 11.8 0.2 0.73 9.8 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKF95689.1 - 2.2e-26 90.5 17.5 2.6e-05 23.8 0.0 11.7 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 KKF95689.1 - 4.1e-26 88.9 17.0 0.0014 18.6 0.0 13.0 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 KKF95689.1 - 3.7e-18 64.2 18.3 0.0071 16.5 0.0 12.5 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKF95689.1 - 6e-16 57.9 3.2 0.0021 17.7 0.0 7.7 8 0 0 8 8 7 4 TPR repeat TPR_7 PF13176.6 KKF95689.1 - 7.3e-16 57.0 5.0 0.005 16.8 0.0 7.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKF95689.1 - 3.7e-15 55.3 10.2 0.00033 21.2 0.0 10.9 11 1 1 12 12 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKF95689.1 - 9.3e-14 51.7 22.3 0.0098 16.4 0.0 11.4 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKF95689.1 - 6.5e-11 42.4 25.7 0.0029 17.9 0.0 10.4 7 3 6 13 13 12 5 Tetratricopeptide repeat TPR_16 PF13432.6 KKF95689.1 - 2.5e-09 37.6 14.7 0.069 13.8 0.0 9.1 9 2 1 10 10 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 KKF95689.1 - 1.6e-08 34.6 18.3 0.0029 18.1 0.0 9.5 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKF95689.1 - 2.1e-07 30.9 6.8 3.6 8.2 0.0 10.2 13 0 0 13 13 10 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKF95689.1 - 8.2e-06 25.5 25.6 0.9 9.5 0.1 9.6 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_9 PF13371.6 KKF95689.1 - 3.1e-05 24.0 3.5 0.16 12.1 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat RPN6_N PF18055.1 KKF95689.1 - 0.001 19.4 1.9 0.064 13.6 0.2 4.6 5 1 0 5 5 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain Fis1_TPR_C PF14853.6 KKF95689.1 - 0.056 13.5 0.1 10 6.3 0.0 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 KKF95689.1 - 0.24 11.8 1.7 24 5.5 0.1 3.6 3 0 0 3 3 2 0 PPR repeat TPR_3 PF07720.12 KKF95689.1 - 0.31 11.1 9.9 8.5 6.5 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_Bact PF18768.1 KKF95689.1 - 0.74 9.4 2.9 32 4.2 0.2 3.6 3 0 0 3 3 3 0 Helix-turn-helix bacterial domain FAD_binding_6 PF00970.24 KKF95690.1 - 6.1e-29 100.3 0.0 9.3e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KKF95690.1 - 3.2e-27 95.3 0.0 4.6e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KKF95690.1 - 0.00036 20.7 0.0 0.0038 17.3 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Aminotran_1_2 PF00155.21 KKF95691.1 - 6.5e-66 222.9 0.0 7.4e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKF95691.1 - 0.00021 19.9 0.0 0.0006 18.5 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKF95691.1 - 0.00092 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KKF95691.1 - 0.018 14.4 0.0 0.049 12.9 0.0 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KKF95691.1 - 0.019 13.9 0.0 0.084 11.8 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V Ima1_N PF09779.9 KKF95692.1 - 1.9e-36 125.9 1.8 3.8e-36 124.9 1.8 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 KKF95692.1 - 0.87 9.7 3.0 8.1 6.6 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 KKF95692.1 - 5.5 6.8 5.2 8.7 6.2 0.9 3.0 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2407_C PF13373.6 KKF95693.1 - 1.7e-38 132.0 0.0 2.3e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KKF95693.1 - 3e-22 79.1 0.0 4.6e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KKF95693.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like rRNA_proc-arch PF13234.6 KKF95694.1 - 7.7e-72 242.4 0.0 1.7e-71 241.4 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KKF95694.1 - 1.8e-47 161.0 0.2 4.9e-47 159.7 0.2 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KKF95694.1 - 2.4e-20 73.0 0.0 5.1e-19 68.7 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF95694.1 - 5.3e-08 33.2 0.1 8.5e-07 29.3 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF95694.1 - 2.5e-07 30.8 1.1 1.3e-06 28.6 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KKF95694.1 - 0.0012 19.1 0.1 0.062 13.6 0.0 3.2 2 1 1 3 3 3 1 AAA domain ATPase_2 PF01637.18 KKF95694.1 - 0.046 13.6 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CDC27 PF09507.10 KKF95694.1 - 2.1 7.6 22.9 3.2 7.0 22.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 COX7C PF02935.16 KKF95695.1 - 1.3e-16 60.6 2.9 1.6e-16 60.3 2.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc PPR_2 PF13041.6 KKF95696.1 - 9e-12 45.0 1.5 0.00029 20.9 0.1 4.6 3 1 1 4 4 4 4 PPR repeat family PPR PF01535.20 KKF95696.1 - 8.1e-08 32.0 1.4 0.003 17.7 0.0 4.8 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.6 KKF95696.1 - 9.9e-08 32.0 0.4 2.7 8.2 0.0 4.7 4 1 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KKF95696.1 - 0.014 15.1 1.6 3.7 7.3 0.1 3.6 4 0 0 4 4 4 0 PPR repeat PPR_long PF17177.4 KKF95696.1 - 0.11 11.8 0.1 0.62 9.4 0.1 2.2 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP MRP-S25 PF13741.6 KKF95697.1 - 7e-59 199.2 8.8 8.3e-54 182.6 3.6 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KKF95697.1 - 3.3e-05 24.1 1.2 0.0002 21.6 1.2 2.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 zf-CSL PF05207.13 KKF95698.1 - 1.1e-22 79.5 1.7 1.3e-22 79.3 1.7 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.6 KKF95698.1 - 0.028 14.2 2.2 0.047 13.5 2.2 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KKF95698.1 - 0.29 11.1 2.0 0.59 10.1 2.0 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ABC_membrane_2 PF06472.15 KKF95699.1 - 1.5e-100 336.0 0.8 2.2e-100 335.5 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KKF95699.1 - 5.9e-17 62.5 0.0 1.2e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKF95699.1 - 0.00024 21.0 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKF95699.1 - 0.014 15.9 1.2 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKF95699.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KKF95699.1 - 0.079 12.4 0.1 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KKF95699.1 - 0.13 11.6 0.2 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Globin PF00042.22 KKF95700.1 - 0.00013 22.5 0.0 0.00031 21.3 0.0 1.7 2 0 0 2 2 2 1 Globin NAD_binding_1 PF00175.21 KKF95700.1 - 0.00018 22.1 0.0 0.76 10.4 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KKF95700.1 - 0.0011 19.1 0.6 0.03 14.5 0.5 2.7 3 1 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KKF95700.1 - 0.0029 17.9 0.0 0.0079 16.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 KKF95700.1 - 0.053 13.4 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Protoglobin Steroid_dh PF02544.16 KKF95701.1 - 2.5e-17 63.3 1.7 4.2e-11 43.0 0.4 2.5 2 1 1 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KKF95701.1 - 0.021 14.3 1.6 0.046 13.2 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Cu-oxidase_2 PF07731.14 KKF95702.1 - 2.6e-25 88.7 0.5 1.6e-24 86.2 0.6 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KKF95702.1 - 3.7e-06 26.9 4.0 1e-05 25.5 0.4 2.9 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KKF95702.1 - 3.9e-05 23.8 0.0 9.6e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Multicopper oxidase MORN_2 PF07661.13 KKF95702.1 - 0.066 13.5 0.2 15 6.2 0.2 3.0 2 0 0 2 2 2 0 MORN repeat variant BUD22 PF09073.10 KKF95702.1 - 0.24 10.7 5.8 0.32 10.3 5.8 1.1 1 0 0 1 1 1 0 BUD22 PAP2_3 PF14378.6 KKF95703.1 - 1.1e-36 126.3 14.2 1.9e-36 125.6 14.2 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 KKF95703.1 - 0.002 17.9 5.8 0.002 17.9 5.8 2.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KKF95703.1 - 0.021 15.4 0.8 0.021 15.4 0.8 2.8 2 0 0 2 2 2 0 PAP2 superfamily C-terminal RhoGAP PF00620.27 KKF95704.1 - 5e-47 159.5 0.4 1.3e-46 158.2 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KKF95704.1 - 2.3e-11 43.8 15.9 1.9e-07 31.2 3.3 2.7 2 1 0 2 2 2 2 LIM domain TF_Zn_Ribbon PF08271.12 KKF95704.1 - 1.2 8.7 12.6 2.2 7.8 0.9 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding CENP-F_leu_zip PF10473.9 KKF95704.1 - 4.1 7.4 20.8 0.45 10.5 7.6 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLASP_N PF12348.8 KKF95705.1 - 1.6e-131 436.7 0.4 4.2e-90 301.3 0.0 2.8 3 0 0 3 3 3 2 CLASP N terminal HEAT_2 PF13646.6 KKF95705.1 - 4e-06 27.1 5.3 0.05 14.0 0.0 5.3 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 KKF95705.1 - 0.00071 19.6 3.5 3.3 8.2 0.0 6.0 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 KKF95705.1 - 0.0016 18.5 0.1 0.27 11.3 0.0 3.6 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KKF95705.1 - 0.012 15.3 1.2 4.3 7.0 0.0 3.5 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 KKF95705.1 - 0.044 12.3 0.3 0.4 9.2 0.0 2.6 2 1 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.6 KKF95705.1 - 0.047 14.2 4.0 1.8e+02 2.8 0.0 5.6 5 0 0 5 5 5 0 HEAT-like repeat Tti2 PF10521.9 KKF95705.1 - 0.057 13.0 0.1 0.84 9.1 0.0 2.7 3 0 0 3 3 3 0 Tti2 family ESR1_C PF12743.7 KKF95705.1 - 1.3 8.9 4.0 25 4.8 3.4 2.9 3 0 0 3 3 3 0 Oestrogen-type nuclear receptor final C-terminal dbPDZ_assoc PF16610.5 KKF95707.1 - 0.079 13.2 2.5 0.097 12.9 0.1 1.9 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 Iso_dh PF00180.20 KKF95708.1 - 4.7e-99 331.8 0.0 5.9e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 KKF95708.1 - 0.027 14.3 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 ThiF PF00899.21 KKF95709.1 - 1.4e-41 142.5 0.0 2.4e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 KKF95709.1 - 0.00053 19.6 0.1 0.0017 18.0 0.1 1.9 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KKF95709.1 - 0.0018 18.5 0.2 0.039 14.2 0.1 2.6 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KKF95709.1 - 0.0041 17.4 0.1 0.046 14.0 0.1 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KKF95709.1 - 0.042 14.3 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 KKF95709.1 - 0.055 13.1 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MAF_flag10 PF01973.18 KKF95709.1 - 0.056 13.1 0.0 0.53 10.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function DUF115 Melibiase_2 PF16499.5 KKF95709.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A RGS12_us2 PF16611.5 KKF95709.1 - 0.18 12.2 0.1 0.48 10.8 0.1 1.7 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco UL42 PF17638.2 KKF95710.1 - 0.1 12.6 3.6 0.32 11.0 0.4 2.4 2 0 0 2 2 2 0 HCMV UL42 Complex1_LYR PF05347.15 KKF95711.1 - 2.5e-18 65.8 4.3 5.1e-18 64.9 4.3 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KKF95711.1 - 3e-05 24.7 3.0 0.0001 22.9 3.0 2.0 1 0 0 1 1 1 1 Complex1_LYR-like Plasmodium_HRP PF05403.11 KKF95711.1 - 0.002 18.0 6.7 0.0048 16.7 6.7 1.6 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) Complex1_LYR_1 PF13232.6 KKF95711.1 - 0.03 14.9 0.3 0.081 13.5 0.3 1.7 1 0 0 1 1 1 0 Complex1_LYR-like WD40 PF00400.32 KKF95712.1 - 2.9e-09 37.4 1.6 0.0033 18.2 0.0 4.6 4 1 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.6 KKF95712.1 - 0.0054 16.3 0.3 1 8.9 0.0 3.0 3 0 0 3 3 3 1 PQQ-like domain ANAPC4_WD40 PF12894.7 KKF95712.1 - 0.066 13.5 0.0 3 8.2 0.0 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KKF95712.1 - 0.075 11.9 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 KKF95712.1 - 0.28 11.7 1.9 43 4.8 0.0 4.0 4 1 0 4 4 4 0 PQQ-like domain Abhydrolase_2 PF02230.16 KKF95714.1 - 2.8e-48 164.6 0.0 3.6e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 KKF95714.1 - 2.8e-05 23.8 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KKF95714.1 - 0.00032 20.0 0.6 1.2 8.3 0.2 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KKF95714.1 - 0.00036 20.3 0.0 0.0075 16.0 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KKF95714.1 - 0.00066 20.3 0.0 0.00083 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKF95714.1 - 0.014 15.1 1.1 3.9 7.0 0.2 2.5 2 1 1 3 3 3 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKF95714.1 - 0.014 14.9 0.3 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KKF95714.1 - 0.028 14.3 0.0 0.095 12.5 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold ATP12 PF07542.11 KKF95716.1 - 4.3e-39 133.5 0.2 9.5e-39 132.4 0.2 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein Semialdhyde_dhC PF02774.18 KKF95717.1 - 7.8e-40 136.9 0.0 1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KKF95717.1 - 3.8e-29 101.6 0.0 2.6e-28 98.9 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 KKF95718.1 - 2.4e-46 158.4 0.0 7.4e-46 156.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KKF95718.1 - 3.9e-05 23.4 0.0 5.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase zf-RING_6 PF14835.6 KKF95718.1 - 0.32 10.9 1.1 0.74 9.7 1.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4595 PF15283.6 KKF95719.1 - 0.08 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold NUDIX PF00293.28 KKF95720.1 - 2.2e-17 63.3 0.1 3.1e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain CBFD_NFYB_HMF PF00808.23 KKF95721.1 - 1.2e-16 60.7 0.3 1.2e-16 60.7 0.3 1.8 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKF95721.1 - 0.00014 22.3 0.2 0.00038 20.8 0.0 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 adh_short PF00106.25 KKF95722.1 - 1e-40 139.3 0.3 1.2e-40 139.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF95722.1 - 9.7e-32 110.4 0.6 1.2e-31 110.1 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF95722.1 - 7.8e-09 35.7 0.3 1.1e-08 35.2 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KKF95722.1 - 0.00011 22.1 0.4 0.00016 21.7 0.4 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KKF95722.1 - 0.0014 18.2 0.4 0.0055 16.3 0.4 1.9 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KKF95722.1 - 0.0086 15.6 0.1 0.057 12.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glyco_transf_4 PF13439.6 KKF95722.1 - 0.025 14.6 0.1 0.95 9.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 THF_DHG_CYH_C PF02882.19 KKF95722.1 - 0.098 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SH3_9 PF14604.6 KKF95723.1 - 2e-06 27.6 0.1 3.9e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKF95723.1 - 5.3e-06 25.9 0.2 1.3e-05 24.7 0.2 1.8 1 0 0 1 1 1 1 SH3 domain Pkinase PF00069.25 KKF95724.1 - 1.1e-21 77.5 0.0 1.7e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KKF95724.1 - 2.8e-09 37.5 18.7 1.6e-05 25.5 0.0 6.5 7 0 0 7 7 7 2 WD domain, G-beta repeat HEAT PF02985.22 KKF95724.1 - 3.4e-07 30.0 10.4 0.023 14.9 0.2 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KKF95724.1 - 7.6e-06 26.2 1.5 0.37 11.2 0.1 3.9 4 0 0 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 KKF95724.1 - 1.7e-05 24.3 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 KKF95724.1 - 0.0006 20.3 1.9 0.012 16.1 0.3 2.8 2 0 0 2 2 2 1 HEAT-like repeat RTP1_C1 PF10363.9 KKF95724.1 - 0.0041 17.3 1.6 0.051 13.7 0.0 2.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KKF95724.1 - 0.016 15.3 0.0 34 4.4 0.0 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Ge1_WD40 PF16529.5 KKF95724.1 - 0.063 12.2 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Kinase-like PF14531.6 KKF95724.1 - 0.086 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like BNR_2 PF13088.6 KKF95725.1 - 0.00044 19.6 0.1 0.0031 16.8 0.1 2.3 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KKF95725.1 - 0.0022 17.7 2.7 1.3 9.3 0.1 3.5 3 0 0 3 3 3 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KKF95725.1 - 0.0072 15.2 0.1 1.3 7.7 0.0 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Flavokinase PF01687.17 KKF95726.1 - 2.5e-10 40.6 0.0 4.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase CRISPR_Cse1 PF09481.10 KKF95726.1 - 0.021 13.9 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) Na_H_Exchanger PF00999.21 KKF95728.1 - 1.2e-27 96.8 32.9 1.8e-27 96.2 32.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family EMC1_C PF07774.13 KKF95729.1 - 2.2e-15 56.9 0.0 4.9e-09 36.2 0.0 2.6 2 1 1 3 3 3 2 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KKF95729.1 - 1.8e-12 47.4 8.0 7.5e-11 42.1 0.3 3.4 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KKF95729.1 - 0.0007 19.4 0.4 0.12 12.4 0.0 4.1 5 0 0 5 5 5 1 PQQ enzyme repeat PQQ_3 PF13570.6 KKF95729.1 - 0.003 18.0 6.8 0.35 11.4 0.0 5.5 7 0 0 7 7 7 1 PQQ-like domain Phosducin PF02114.16 KKF95731.1 - 6.5e-12 44.9 0.0 8.6e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KKF95731.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Ribosomal_S27e PF01667.17 KKF95732.1 - 3.4e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 KKF95732.1 - 0.14 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 KKF95732.1 - 0.8 9.7 6.5 2.7 8.0 4.3 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type SIP1 PF04938.12 KKF95733.1 - 1.2e-07 31.7 0.0 3.8e-05 23.5 0.0 3.0 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Atg29_N PF18388.1 KKF95734.1 - 3.1e-23 81.3 0.5 3.1e-23 81.3 0.5 2.1 2 0 0 2 2 2 1 Atg29 N-terminal domain Acetyltransf_7 PF13508.7 KKF95735.1 - 2e-05 24.9 0.0 4.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKF95735.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKF95735.1 - 0.0037 17.3 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKF95735.1 - 0.022 15.0 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 KKF95735.1 - 0.08 12.9 0.0 0.26 11.3 0.0 2.0 1 1 0 1 1 1 0 FR47-like protein DAO PF01266.24 KKF95736.1 - 1.4e-35 123.5 1.2 1.6e-35 123.3 1.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKF95736.1 - 2.5e-05 23.6 1.3 3.4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KKF95736.1 - 0.0021 18.2 0.0 0.0055 16.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KKF95736.1 - 0.0038 16.9 0.0 0.0088 15.7 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KKF95736.1 - 0.0082 16.7 0.1 0.033 14.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKF95736.1 - 0.027 13.7 0.1 0.17 11.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KKF95736.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 KKF95736.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ALG3 PF05208.13 KKF95737.1 - 1.1e-125 419.8 22.1 1.3e-125 419.5 22.1 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 KKF95738.1 - 2.8e-14 52.7 0.1 3.8e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Sin_N PF04801.13 KKF95739.1 - 2.2e-19 70.0 0.0 4.3e-19 69.0 0.0 1.5 1 1 0 1 1 1 1 Sin-like protein conserved region Gp45_2 PF17470.2 KKF95739.1 - 0.013 15.4 0.1 0.03 14.3 0.1 1.6 1 0 0 1 1 1 0 Phage gene product 45.2 PAT1 PF09770.9 KKF95740.1 - 0 1100.9 13.1 0 1092.8 13.1 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF3313 PF11769.8 KKF95740.1 - 0.099 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Glyco_transf_15 PF01793.16 KKF95741.1 - 1.8e-129 431.6 7.4 2.3e-129 431.3 7.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.7 KKF95741.1 - 0.17 12.1 0.9 0.3 11.3 0.9 1.4 1 0 0 1 1 1 0 EGF domain Ribosom_S12_S23 PF00164.25 KKF95742.1 - 1.7e-30 105.0 1.2 3.6e-30 103.9 0.7 1.7 1 1 1 2 2 2 1 Ribosomal protein S12/S23 Acyl-CoA_dh_1 PF00441.24 KKF95743.1 - 2.5e-41 141.4 4.8 3.9e-41 140.8 4.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKF95743.1 - 3e-24 85.9 0.0 8.5e-24 84.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KKF95743.1 - 6.3e-24 84.0 0.0 1.3e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKF95743.1 - 4.4e-17 62.6 0.5 5.9e-17 62.2 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KKF95743.1 - 0.0065 16.2 0.1 0.017 14.8 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 KKF95743.1 - 0.009 16.0 1.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Staphylococcal AgrD protein Hydrolase_4 PF12146.8 KKF95744.1 - 1.6e-13 50.5 0.0 3.6e-13 49.3 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKF95744.1 - 1.1e-10 41.6 0.2 2.2e-10 40.6 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKF95744.1 - 1.1e-06 29.4 0.0 1.5e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KKF95744.1 - 0.00012 21.8 0.4 0.0074 15.9 0.2 2.9 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 KKF95744.1 - 0.0024 17.6 0.0 0.0087 15.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 KKF95744.1 - 0.0028 17.2 0.0 0.0069 15.9 0.0 1.5 2 0 0 2 2 2 1 Lipase (class 2) Peptidase_S15 PF02129.18 KKF95744.1 - 0.025 14.2 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KKF95744.1 - 0.026 14.2 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase tRNA-synt_His PF13393.6 KKF95745.1 - 2.3e-38 132.2 0.0 2.2e-32 112.6 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KKF95745.1 - 1.4e-08 34.8 0.0 3.9e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KKF95745.1 - 0.00057 19.9 0.0 0.0012 18.9 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 KKF95745.1 - 0.0075 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs LNS2 PF08235.13 KKF95747.1 - 6.9e-94 313.5 0.0 9.2e-94 313.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KKF95747.1 - 1.3e-42 143.9 0.0 3.7e-42 142.4 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KKF95747.1 - 0.018 14.7 0.0 0.74 9.4 0.0 2.6 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Nop14 PF04147.12 KKF95747.1 - 0.4 8.8 17.5 0.67 8.1 17.5 1.2 1 0 0 1 1 1 0 Nop14-like family tRNA_U5-meth_tr PF05958.11 KKF95748.1 - 1.3e-12 47.4 0.0 2.4e-11 43.2 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KKF95748.1 - 5.3e-07 29.4 0.0 1.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KKF95748.1 - 2.2e-05 24.3 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF95748.1 - 0.00023 21.8 0.0 0.0005 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltrans_SAM PF10672.9 KKF95748.1 - 0.0017 17.5 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase PrmA PF06325.13 KKF95748.1 - 0.002 17.5 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KKF95748.1 - 0.012 16.2 0.0 0.027 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KKF95748.1 - 0.04 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UNC45-central PF11701.8 KKF95749.1 - 1.2e-53 181.2 0.0 8.6e-52 175.2 0.0 3.1 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KKF95749.1 - 1.6e-06 27.9 5.5 0.57 10.3 0.0 6.5 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Tfb4 PF03850.14 KKF95750.1 - 2.4e-92 309.4 0.1 2.8e-92 309.1 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 ChitinaseA_N PF08329.10 KKF95750.1 - 0.0037 16.9 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Chitinase A, N-terminal domain Actin PF00022.19 KKF95751.1 - 3.4e-88 296.0 0.0 5.8e-53 180.0 0.0 2.0 1 1 1 2 2 2 2 Actin Glyco_transf_34 PF05637.12 KKF95752.1 - 8.3e-67 225.4 0.0 1e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Proteasome PF00227.26 KKF95753.1 - 1.6e-58 197.3 0.0 4.5e-34 117.6 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KKF95753.1 - 1.1e-10 41.0 0.2 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribonuclease_3 PF00636.26 KKF95754.1 - 1.2e-41 141.6 0.0 1.2e-20 74.1 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKF95754.1 - 4.3e-28 98.0 0.0 1.2e-11 44.8 0.0 3.5 3 1 0 3 3 3 3 Ribonuclease-III-like Rgp1 PF08737.10 KKF95755.1 - 1.3e-113 380.3 0.1 6.6e-70 236.4 0.0 2.3 1 1 1 2 2 2 2 Rgp1 zf-CCHC PF00098.23 KKF95756.1 - 0.0003 20.7 4.2 0.00048 20.1 4.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 KKF95756.1 - 0.00036 20.2 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_6 PF15288.6 KKF95756.1 - 0.00055 19.7 1.4 0.0019 18.0 1.4 1.9 1 0 0 1 1 1 1 Zinc knuckle HscB_4_cys PF18256.1 KKF95756.1 - 0.059 13.2 2.0 0.11 12.3 2.0 1.4 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif zf-CCHC_4 PF14392.6 KKF95756.1 - 0.13 12.0 1.1 0.26 11.0 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4604 PF15377.6 KKF95756.1 - 2.6 8.4 24.2 0.18 12.2 15.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) T3SS_needle_F PF09392.10 KKF95756.1 - 4.6 7.5 7.6 0.38 11.0 0.3 2.9 2 1 1 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF WD40 PF00400.32 KKF95757.1 - 6.7e-06 26.8 0.5 2.2 9.3 0.1 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat DUF5046 PF16465.5 KKF95757.1 - 0.1 12.0 2.0 14 5.1 0.0 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF5046) Neugrin PF06413.11 KKF95758.1 - 1.1e-09 38.6 0.3 1.1e-09 38.6 0.3 2.1 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 KKF95758.1 - 5.3e-06 26.7 2.1 8.3e-06 26.1 0.1 2.2 1 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Calcipressin PF04847.12 KKF95759.1 - 1.6e-45 155.1 0.2 2.3e-45 154.6 0.2 1.1 1 0 0 1 1 1 1 Calcipressin p450 PF00067.22 KKF95760.1 - 6.3e-34 117.5 0.0 2.1e-33 115.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 His_Phos_1 PF00300.22 KKF95763.1 - 5.9e-20 71.8 1.2 1.4e-19 70.6 0.2 2.0 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) VHS PF00790.19 KKF95764.1 - 5.4e-39 133.3 4.3 6.9e-39 132.9 0.5 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KKF95764.1 - 2.6e-16 59.5 1.9 4.6e-16 58.7 1.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KKF95764.1 - 1.9e-06 27.4 15.3 0.0023 17.8 1.9 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 KKF95764.1 - 3.7e-05 23.9 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 GAT domain FYVE_2 PF02318.16 KKF95764.1 - 0.24 11.6 1.8 0.24 11.6 0.4 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.11 KKF95764.1 - 0.97 9.4 3.7 4.2 7.4 3.3 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UCH PF00443.29 KKF95765.1 - 1.9e-14 53.8 0.0 3.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKF95765.1 - 3.5e-14 53.1 0.0 5.3e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 KKF95765.1 - 0.0014 18.8 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain AMP-binding PF00501.28 KKF95766.1 - 1e-83 281.3 0.1 1.4e-83 280.8 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF3295 PF11702.8 KKF95767.1 - 9.8e-112 374.8 29.2 1.8e-111 374.0 29.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KKF95767.1 - 3.2e-11 42.8 1.0 6.3e-11 41.9 1.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cpn60_TCP1 PF00118.24 KKF95768.1 - 2.3e-158 527.9 5.2 2.6e-158 527.7 5.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GTP_EFTU PF00009.27 KKF95769.1 - 2.8e-33 115.1 0.0 6e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KKF95769.1 - 1.9e-09 37.7 10.7 0.00049 20.3 0.1 2.8 2 1 0 2 2 2 2 HBS1 N-terminus GTP_EFTU_D2 PF03144.25 KKF95769.1 - 1.5e-07 31.7 0.3 3.8e-07 30.4 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KKF95769.1 - 6e-06 26.5 0.0 1.6e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KKF95769.1 - 0.0012 18.9 0.3 0.015 15.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KKF95769.1 - 0.035 13.7 0.9 0.057 13.0 0.1 1.7 2 0 0 2 2 2 0 Ras family CDC48_2 PF02933.17 KKF95769.1 - 0.11 12.3 0.1 4.1 7.2 0.0 2.7 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 HSP70 PF00012.20 KKF95770.1 - 1.6e-259 862.1 10.0 1.9e-259 861.9 10.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKF95770.1 - 3.4e-17 62.2 1.1 1.9e-15 56.6 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Radial_spoke_3 PF06098.11 KKF95770.1 - 0.0078 15.5 3.5 0.0078 15.5 3.5 1.6 2 0 0 2 2 2 1 Radial spoke protein 3 Hydantoinase_A PF01968.18 KKF95770.1 - 0.015 14.6 0.4 0.74 9.0 0.1 2.6 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.6 KKF95770.1 - 0.016 15.6 5.4 20 5.6 0.2 3.9 3 2 0 3 3 3 0 Cell division protein FtsA DDR PF08841.10 KKF95770.1 - 0.016 14.2 0.4 0.2 10.6 0.2 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF357 PF04010.13 KKF95770.1 - 0.13 12.3 0.7 2.2 8.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Abhydrolase_6 PF12697.7 KKF95771.1 - 2.8e-08 34.6 2.6 3.6e-08 34.3 2.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKF95771.1 - 5e-08 32.9 0.1 1.5e-06 28.1 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KKF95771.1 - 1.6e-05 24.8 0.1 2e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKF95771.1 - 6.4e-05 22.3 0.1 0.00026 20.3 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KKF95771.1 - 0.021 14.7 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 KKF95771.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.5 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase LRR_4 PF12799.7 KKF95772.1 - 1.3e-30 104.9 29.4 3e-08 33.8 1.9 6.5 4 1 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKF95772.1 - 1.2e-18 66.6 26.8 3e-07 30.1 4.8 6.2 1 1 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KKF95772.1 - 3.4e-16 59.3 31.6 8.2e-09 35.2 4.8 3.9 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 KKF95772.1 - 0.00013 21.7 21.0 0.082 13.0 0.5 6.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 KKF95772.1 - 0.058 14.0 21.6 31 5.6 0.8 8.1 8 1 0 8 8 8 0 Leucine Rich Repeat ABC_membrane_2 PF06472.15 KKF95773.1 - 1.8e-92 309.5 0.1 1.8e-92 309.5 0.1 1.7 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KKF95773.1 - 6.7e-16 59.0 0.0 3.5e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KKF95773.1 - 0.0087 16.5 0.3 0.022 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain End3 PF12761.7 KKF95773.1 - 0.018 15.2 0.8 0.087 13.0 1.2 1.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 AAA_23 PF13476.6 KKF95773.1 - 0.045 14.3 0.6 2.6 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain GPS2_interact PF15784.5 KKF95773.1 - 0.06 13.8 1.7 0.12 12.8 1.7 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain AAA_29 PF13555.6 KKF95773.1 - 0.093 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NIF PF03031.18 KKF95774.1 - 3.4e-54 182.8 0.1 4.6e-54 182.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec61_beta PF03911.16 KKF95775.1 - 2.4e-19 69.1 1.4 3.5e-19 68.6 1.4 1.3 1 0 0 1 1 1 1 Sec61beta family GSK-3_bind PF05350.12 KKF95775.1 - 0.078 12.3 2.4 0.097 12.0 2.4 1.1 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Glyco_transf_28 PF03033.20 KKF95776.1 - 9.6e-19 67.8 0.3 5.7e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KKF95776.1 - 3.7e-06 26.0 0.1 6.2e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KKF95776.1 - 0.054 13.8 0.0 0.22 11.9 0.0 2.1 1 1 0 1 1 1 0 Autophagy-related protein C terminal domain RCR PF12273.8 KKF95777.1 - 4.4e-11 43.5 8.1 8.4e-11 42.6 8.1 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TFIIA PF03153.13 KKF95778.1 - 0.34 10.8 20.9 0.47 10.4 20.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCCH_3 PF15663.5 KKF95778.1 - 0.56 10.4 2.9 0.34 11.1 1.1 1.6 2 0 0 2 2 2 0 Zinc-finger containing family Ndc1_Nup PF09531.10 KKF95778.1 - 1.7 7.2 10.8 2 7.0 10.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF945 PF06097.11 KKF95778.1 - 3.4 6.7 11.4 5 6.1 11.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) PAT1 PF09770.9 KKF95778.1 - 7.4 4.7 20.5 8.1 4.6 20.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 tRNA-synt_2c PF01411.19 KKF95779.1 - 1.3e-211 703.9 0.8 1.6e-211 703.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KKF95779.1 - 7.7e-16 57.9 0.2 1.9e-15 56.6 0.2 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KKF95779.1 - 1.7e-12 47.9 3.2 4.5e-12 46.6 3.2 1.8 1 0 0 1 1 1 1 DHHA1 domain Asp_Glu_race_2 PF14669.6 KKF95779.1 - 0.1 12.3 0.4 0.7 9.5 0.2 2.1 2 0 0 2 2 2 0 Putative aspartate racemase DKNYY PF13644.6 KKF95779.1 - 1.5 9.6 6.8 4.1 8.2 1.8 2.9 1 1 1 2 2 2 0 DKNYY family Methyltransf_28 PF02636.17 KKF95780.1 - 1.1e-42 146.5 0.0 1.8e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KKF95780.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 KKF95780.1 - 0.12 13.1 0.0 0.24 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KKF95780.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PALP PF00291.25 KKF95781.1 - 1.4e-60 205.2 1.7 1.7e-60 204.9 1.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TFIIS_M PF07500.14 KKF95782.1 - 4.1e-29 101.3 0.8 4.1e-29 101.3 0.8 2.4 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KKF95782.1 - 3.1e-17 62.1 9.0 5e-17 61.5 9.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KKF95782.1 - 3.5e-09 36.5 0.2 1.1e-08 34.9 0.2 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 KKF95782.1 - 0.25 11.0 2.2 2.3 8.0 0.3 2.3 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain HalOD2 PF18547.1 KKF95782.1 - 1.7 8.6 7.7 0.25 11.3 0.3 2.5 2 0 0 2 2 2 0 Halobacterial output domain 2 XRN_M PF17846.1 KKF95782.1 - 1.8 7.4 5.5 0.54 9.2 2.6 1.5 1 1 1 2 2 2 0 Xrn1 helical domain DUF3827 PF12877.7 KKF95782.1 - 5.5 5.2 15.1 10 4.4 15.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) ASD2 PF08687.11 KKF95782.1 - 6.5 6.2 11.1 1.8 8.0 2.5 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Mto2_bdg PF12808.7 KKF95782.1 - 8.8 6.7 8.1 1.6 9.1 0.4 3.3 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Pex2_Pex12 PF04757.14 KKF95783.1 - 2e-34 119.2 0.2 3.6e-34 118.3 0.2 1.5 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region IBN_N PF03810.19 KKF95783.1 - 6.5e-13 48.4 0.0 8.8e-12 44.8 0.0 3.1 3 1 1 4 4 4 1 Importin-beta N-terminal domain zf-C3HC4_4 PF15227.6 KKF95783.1 - 0.022 14.9 5.1 0.048 13.8 5.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Cse1 PF08506.10 KKF95783.1 - 0.048 12.5 0.1 0.3 9.9 0.0 2.1 2 0 0 2 2 2 0 Cse1 zf-RING_UBOX PF13445.6 KKF95783.1 - 0.15 12.1 0.5 0.51 10.4 0.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Aldedh PF00171.22 KKF95784.1 - 3.8e-133 444.4 5.7 4.5e-133 444.1 5.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAA_hydrolase PF01557.18 KKF95786.1 - 2.8e-35 122.0 0.0 4.1e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KKF95786.1 - 4.5e-27 94.3 0.0 8.7e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Kelch_4 PF13418.6 KKF95787.1 - 2.7e-34 116.9 11.2 3.2e-09 36.7 0.7 6.1 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KKF95787.1 - 9.8e-31 105.1 4.4 5.8e-15 54.6 0.2 5.7 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KKF95787.1 - 9.8e-28 95.5 11.2 6.8e-12 45.2 0.7 6.3 4 2 1 5 5 5 5 Kelch motif Kelch_5 PF13854.6 KKF95787.1 - 1.9e-27 94.8 2.8 5.4e-08 32.6 0.2 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 KKF95787.1 - 1.8e-26 91.9 9.4 3.7e-06 27.1 0.1 6.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KKF95787.1 - 6.4e-22 76.6 5.1 1.7e-09 37.3 0.4 5.7 5 1 0 5 5 5 4 Kelch motif Raptor_N PF14538.6 KKF95788.1 - 1.5e-62 209.9 0.0 2.9e-62 209.0 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain ANAPC4_WD40 PF12894.7 KKF95788.1 - 1.6e-08 34.7 0.0 1.8 8.9 0.0 4.7 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKF95788.1 - 2e-06 28.4 3.1 17 6.5 0.0 6.2 6 0 0 6 6 6 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 KKF95788.1 - 0.00015 21.8 0.0 0.72 9.9 0.0 2.7 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KKF95788.1 - 0.016 13.9 0.1 0.031 12.9 0.1 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KKF95788.1 - 1.9 9.1 5.4 24 5.6 0.7 3.3 3 0 0 3 3 3 0 PQQ-like domain HET PF06985.11 KKF95789.1 - 3.1e-21 76.3 0.4 6e-21 75.3 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PTR2 PF00854.21 KKF95790.1 - 3.8e-73 246.6 8.9 5.7e-73 246.0 8.9 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KKF95790.1 - 0.0046 15.9 28.5 0.017 14.0 23.2 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PI3_PI4_kinase PF00454.27 KKF95791.1 - 4.6e-49 167.5 0.0 1.1e-48 166.3 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KKF95791.1 - 2.9e-24 85.9 2.6 7.4e-24 84.6 0.4 2.3 2 0 0 2 2 2 1 FAT domain UME PF08064.13 KKF95791.1 - 1.2e-23 83.0 4.4 2.2e-23 82.1 1.7 2.8 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 KKF95791.1 - 8.6e-16 57.5 0.0 2.6e-15 55.9 0.0 1.9 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 KKF95791.1 - 0.0072 16.8 0.2 0.57 10.7 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-PARP PF00645.18 KKF95792.1 - 5.8e-20 71.9 1.7 1.6e-19 70.6 1.7 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.19 KKF95792.1 - 5.8e-13 47.1 100.8 0.048 13.5 1.0 11.1 10 0 0 10 10 10 10 AT hook motif Dynamin_N PF00350.23 KKF95793.1 - 0.21 11.7 0.0 0.29 11.2 0.0 1.1 1 0 0 1 1 1 0 Dynamin family GFO_IDH_MocA PF01408.22 KKF95795.1 - 1.1e-26 94.0 0.0 1.9e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKF95795.1 - 2.2e-09 37.4 0.1 1.4e-08 34.7 0.0 2.2 3 0 0 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KKF95795.1 - 0.00059 20.5 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KKF95795.1 - 0.0042 17.3 0.0 0.0078 16.5 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain OCD_Mu_crystall PF02423.15 KKF95795.1 - 0.052 12.5 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Acyltransferase PF01553.21 KKF95796.1 - 2.3e-24 85.5 0.0 3.5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KKF95796.1 - 1.8e-13 50.3 0.2 3.3e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 KKF95797.1 - 1.6e-49 168.7 0.0 9.5e-49 166.2 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KKF95797.1 - 0.21 11.2 0.1 0.39 10.3 0.1 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Lactonase PF10282.9 KKF95798.1 - 5.3e-80 269.3 0.2 6.6e-80 268.9 0.2 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller 4HBT PF03061.22 KKF95799.1 - 5.8e-05 23.4 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily ASXH PF13919.6 KKF95800.1 - 0.0045 17.0 0.1 0.36 10.9 0.0 2.1 1 1 0 2 2 2 2 Asx homology domain TSC21 PF15217.6 KKF95800.1 - 0.0085 16.1 0.0 2.6 7.9 0.0 2.1 2 0 0 2 2 2 2 TSC21 family NDK PF00334.19 KKF95802.1 - 1.1e-52 177.6 0.0 1.2e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DivIC PF04977.15 KKF95803.1 - 0.058 13.2 0.1 0.058 13.2 0.1 2.8 2 1 0 2 2 2 0 Septum formation initiator DUF2681 PF10883.8 KKF95803.1 - 0.39 11.1 0.0 0.39 11.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) LapA_dom PF06305.11 KKF95803.1 - 3.8 7.4 0.0 3.8 7.4 0.0 2.6 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MS_channel PF00924.18 KKF95804.1 - 9e-19 67.8 2.4 1.4e-18 67.2 2.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KKF95804.1 - 0.001 18.4 0.1 0.001 18.4 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 KKF95804.1 - 0.0015 18.0 0.5 0.0015 18.0 0.5 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KKF95804.1 - 0.0043 16.9 0.0 0.02 14.8 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KKF95804.1 - 0.0055 17.1 2.0 0.0083 16.6 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KKF95804.1 - 0.73 9.7 2.5 6.6 6.7 1.5 2.4 2 0 0 2 2 2 0 EF-hand domain pair Glyco_hydro_31 PF01055.26 KKF95805.1 - 3.2e-140 468.2 3.7 4.7e-140 467.7 3.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KKF95805.1 - 4.5e-25 87.8 0.2 1e-23 83.4 0.1 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KKF95805.1 - 2.2e-06 27.9 0.9 6.4e-06 26.3 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Globin PF00042.22 KKF95805.1 - 0.11 13.1 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Globin Fungal_trans PF04082.18 KKF95808.1 - 5.9e-24 84.5 0.5 4e-23 81.8 0.0 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF95808.1 - 1.8e-08 34.4 15.0 3.3e-08 33.5 15.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Centro_C10orf90 PF17730.1 KKF95808.1 - 0.0078 15.1 1.9 0.016 14.0 1.9 1.4 1 0 0 1 1 1 1 Centrosomal C10orf90 SUIM_assoc PF16619.5 KKF95808.1 - 1.7 8.7 9.0 2.4 8.3 3.3 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_M41 PF01434.18 KKF95809.1 - 3.9e-67 225.8 0.0 8.4e-67 224.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KKF95809.1 - 1.3e-42 145.3 0.0 4.5e-42 143.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKF95809.1 - 1.4e-12 47.2 0.0 4.5e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KKF95809.1 - 1.1e-09 38.6 0.0 2.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 KKF95809.1 - 0.0011 19.0 0.0 0.0034 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KKF95809.1 - 0.0024 17.6 0.7 0.11 12.2 0.1 2.8 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 KKF95809.1 - 0.0044 17.4 0.0 0.24 11.8 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KKF95809.1 - 0.0063 16.3 0.0 0.036 13.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KKF95809.1 - 0.0073 15.5 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KKF95809.1 - 0.028 14.7 0.1 1.2 9.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KKF95809.1 - 0.061 13.4 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_11 PF13086.6 KKF95809.1 - 0.84 9.4 5.9 9.4 5.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain HCO3_cotransp PF00955.21 KKF95810.1 - 5.6e-86 289.4 9.1 2.3e-45 155.4 3.7 2.8 1 1 1 2 2 2 2 HCO3- transporter family FA_desaturase PF00487.24 KKF95811.1 - 2.5e-28 99.6 26.1 3.9e-28 99.0 26.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KKF95811.1 - 0.0001 22.5 0.2 0.00034 20.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Homeodomain PF00046.29 KKF95812.1 - 1.1e-17 63.5 4.7 2.1e-17 62.7 4.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KKF95812.1 - 0.09 12.7 1.3 0.13 12.2 0.2 1.8 2 0 0 2 2 2 0 Homeobox KN domain 3HCDH_N PF02737.18 KKF95813.1 - 1e-53 181.9 0.6 1.3e-53 181.6 0.6 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKF95813.1 - 1.8e-32 111.8 0.0 7.7e-32 109.8 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKF95813.1 - 0.0068 16.6 0.6 0.019 15.1 0.6 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KKF95813.1 - 0.017 14.5 0.1 0.046 13.1 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KKF95813.1 - 0.29 11.7 2.1 1.1 9.9 1.2 2.3 1 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TIMELESS PF04821.14 KKF95814.1 - 5.2e-69 232.6 0.9 5.2e-69 232.6 0.9 2.5 4 0 0 4 4 4 1 Timeless protein TIMELESS_C PF05029.13 KKF95814.1 - 5.8e-28 98.4 8.0 5.8e-28 98.4 8.0 2.8 3 0 0 3 3 3 1 Timeless protein C terminal region FH2 PF02181.23 KKF95815.1 - 6.1e-88 295.4 3.9 6.1e-88 295.4 3.9 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KKF95815.1 - 1.4e-60 204.1 0.1 1.4e-60 204.1 0.1 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KKF95815.1 - 9.9e-49 165.6 1.4 3.2e-48 163.9 1.1 2.1 1 1 1 2 2 2 1 Diaphanous FH3 Domain DUF4048 PF13257.6 KKF95816.1 - 0.0002 21.3 22.0 0.0002 21.3 22.0 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4048) DIOX_N PF14226.6 KKF95817.1 - 9.8e-16 58.6 0.0 1.6e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKF95817.1 - 1e-14 54.8 0.0 2.2e-13 50.6 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.8 KKF95818.1 - 1.3e-56 191.5 0.0 1.9e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KKF95818.1 - 4.5e-22 78.2 0.0 1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KKF95818.1 - 0.00099 19.5 0.0 0.008 16.6 0.0 2.5 3 0 0 3 3 3 1 XPG N-terminal domain PT PF04886.12 KKF95819.1 - 6.4e-27 92.8 48.5 6e-05 22.5 3.6 10.0 5 3 1 6 6 6 5 PT repeat Synapsin_N PF10581.9 KKF95819.1 - 0.059 13.3 57.4 7.4 6.6 0.3 11.9 6 3 6 12 12 12 0 Synapsin N-terminal DUF3432 PF11914.8 KKF95819.1 - 0.53 10.6 34.9 0.19 12.0 3.9 5.1 3 2 0 4 4 4 0 Domain of unknown function (DUF3432) IF4E PF01652.18 KKF95820.1 - 1.7e-55 187.2 0.5 2.5e-55 186.6 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Syntaxin-6_N PF09177.11 KKF95821.1 - 9.7e-26 90.2 2.9 2e-24 86.0 0.1 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KKF95821.1 - 9.5e-05 22.3 0.6 9.5e-05 22.3 0.6 1.8 2 0 0 2 2 2 1 SNARE domain ATG16 PF08614.11 KKF95821.1 - 0.0026 18.0 9.0 0.044 14.0 2.7 2.2 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) Filament PF00038.21 KKF95821.1 - 0.0033 17.1 2.5 0.02 14.5 1.1 2.2 2 1 0 2 2 2 1 Intermediate filament protein UPF0242 PF06785.11 KKF95821.1 - 0.017 15.3 0.8 0.57 10.3 1.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Use1 PF09753.9 KKF95821.1 - 0.051 13.3 0.8 0.065 13.0 0.8 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Herpes_UL6 PF01763.16 KKF95821.1 - 0.071 11.6 0.7 0.1 11.1 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Prominin PF05478.11 KKF95821.1 - 0.081 10.9 1.4 0.09 10.7 0.2 1.6 2 0 0 2 2 2 0 Prominin TBCA PF02970.16 KKF95821.1 - 1 9.7 5.4 1.2 9.5 3.0 2.2 2 1 0 2 2 2 0 Tubulin binding cofactor A GLE1 PF07817.13 KKF95822.1 - 1.6e-49 168.4 0.0 2.2e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 GLE1-like protein Nucleoporin_FG PF13634.6 KKF95822.1 - 0.21 12.4 28.4 7.4 7.5 28.4 2.5 1 1 0 1 1 1 0 Nucleoporin FG repeat region RNB PF00773.19 KKF95823.1 - 1.6e-65 221.6 0.0 2.6e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KKF95823.1 - 1.5e-26 92.2 0.0 3.4e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KKF95823.1 - 1.3e-24 86.3 0.0 1.3e-24 86.3 0.0 2.3 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KKF95823.1 - 3.1e-08 33.6 0.0 0.00023 21.2 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KKF95823.1 - 0.035 13.8 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 Rrp44-like cold shock domain DUF5032 PF16435.5 KKF95823.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5032) Ferritin_2 PF13668.6 KKF95824.1 - 1.4e-35 122.5 0.1 2.1e-35 121.9 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain UCH PF00443.29 KKF95825.1 - 4.6e-26 91.9 0.0 6.6e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KKF95825.1 - 2.3e-12 47.0 0.1 4.3e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KKF95825.1 - 0.0029 17.3 0.1 0.023 14.3 0.0 2.2 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UVR PF02151.19 KKF95825.1 - 0.059 13.1 1.1 0.13 12.0 1.1 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Utp13 PF08625.11 KKF95826.1 - 2.5e-51 173.3 0.3 4e-51 172.7 0.3 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KKF95826.1 - 9.8e-49 162.3 24.9 7e-05 23.5 0.0 13.1 12 2 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF95826.1 - 6.5e-11 42.4 7.9 0.077 13.3 0.0 8.1 7 3 2 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KKF95826.1 - 0.00032 19.6 9.0 1 8.0 0.0 5.7 5 2 2 7 7 7 2 Nup133 N terminal like Nup160 PF11715.8 KKF95826.1 - 0.0018 17.0 9.8 0.58 8.7 0.8 5.1 3 2 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKF95826.1 - 0.16 10.9 3.6 6.4 5.6 0.0 4.0 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Adap_comp_sub PF00928.21 KKF95828.1 - 7.5e-84 281.2 0.0 9.1e-84 280.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KKF95828.1 - 0.023 14.6 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain RIBIOP_C PF04950.12 KKF95828.1 - 0.095 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal ABC_tran PF00005.27 KKF95829.1 - 9.3e-47 159.0 0.0 6.5e-22 78.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KKF95829.1 - 2e-21 75.8 0.5 2e-21 75.8 0.5 2.7 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KKF95829.1 - 3.7e-18 66.4 0.1 0.00025 21.0 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKF95829.1 - 1.2e-11 44.5 0.0 0.0022 17.4 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKF95829.1 - 8.3e-09 36.2 1.4 0.02 15.4 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KKF95829.1 - 4.4e-08 32.7 0.0 0.01 15.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KKF95829.1 - 8.7e-07 29.5 0.5 0.0085 16.5 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKF95829.1 - 1.9e-06 27.9 0.0 0.0061 16.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKF95829.1 - 4.1e-06 26.9 0.0 0.016 15.3 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KKF95829.1 - 6.4e-06 26.5 0.0 0.048 13.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 KKF95829.1 - 1.5e-05 24.9 0.2 0.27 10.9 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 KKF95829.1 - 4.1e-05 23.9 0.0 0.024 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KKF95829.1 - 5e-05 23.3 0.1 0.3 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKF95829.1 - 6.1e-05 23.6 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KKF95829.1 - 8.6e-05 23.0 0.0 0.68 10.4 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KKF95829.1 - 9e-05 22.5 0.1 0.2 11.6 0.0 2.5 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KKF95829.1 - 0.00039 20.8 0.4 1.9 8.9 0.0 3.0 3 0 0 3 3 3 2 RNA helicase AAA_24 PF13479.6 KKF95829.1 - 0.0011 18.8 0.6 2 8.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain NB-ARC PF00931.22 KKF95829.1 - 0.0016 17.7 0.0 5.5 6.1 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain AAA_14 PF13173.6 KKF95829.1 - 0.0022 18.0 0.0 3.5 7.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KKF95829.1 - 0.0031 17.7 0.0 2.3 8.5 0.0 3.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 KKF95829.1 - 0.0047 16.5 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKF95829.1 - 0.0055 16.3 0.0 1 8.9 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 KKF95829.1 - 0.0079 16.4 2.7 0.6 10.3 0.1 3.3 4 0 0 4 4 3 1 AAA domain Dynamin_N PF00350.23 KKF95829.1 - 0.01 15.9 0.0 8.3 6.4 0.0 3.4 3 0 0 3 3 3 0 Dynamin family DUF2813 PF11398.8 KKF95829.1 - 0.025 13.8 0.1 2.7 7.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) ATPase_2 PF01637.18 KKF95829.1 - 0.027 14.4 0.2 5.2 6.9 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 KKF95829.1 - 0.028 13.6 0.2 3.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KKF95829.1 - 0.029 13.9 0.0 2.1 7.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KKF95829.1 - 0.044 13.7 0.1 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 NTPase DAP3 PF10236.9 KKF95829.1 - 0.079 12.1 0.1 6.6 5.8 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 FeoB_N PF02421.18 KKF95829.1 - 0.081 12.4 0.1 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_17 PF13207.6 KKF95829.1 - 0.088 13.2 0.0 20 5.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKF95829.1 - 0.11 12.5 0.3 20 5.2 0.0 3.0 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KKF95829.1 - 1.9 8.2 7.2 3.1 7.5 0.1 3.4 4 1 0 4 4 4 0 AAA domain SNF2_N PF00176.23 KKF95830.1 - 2.5e-67 227.1 0.7 4.6e-67 226.2 0.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KKF95830.1 - 2.8e-47 160.4 17.8 2.8e-47 160.4 17.8 5.3 4 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 KKF95830.1 - 2.9e-20 72.7 0.0 7.3e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF95830.1 - 5.4e-08 33.0 1.0 2.8e-07 30.7 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKF95830.1 - 0.011 14.9 0.0 0.011 14.9 0.0 3.1 4 1 0 4 4 4 0 Class II histone deacetylase complex subunits 2 and 3 VID27_PH PF17747.1 KKF95830.1 - 0.018 15.3 1.2 6.2 7.2 0.0 2.8 3 0 0 3 3 3 0 VID27 PH-like domain Fe_hyd_lg_C PF02906.14 KKF95830.1 - 6 6.5 7.4 0.7 9.5 2.0 2.2 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain DUF89 PF01937.19 KKF95831.1 - 9.2e-117 389.9 0.0 1.1e-116 389.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 LIDHydrolase PF10230.9 KKF95832.1 - 1e-52 179.3 0.0 1.4e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KKF95832.1 - 0.033 13.5 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SAP PF02037.27 KKF95834.1 - 2.5e-14 52.6 0.0 4.1e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KKF95834.1 - 0.00018 21.2 1.7 0.00018 21.2 1.7 2.6 2 1 0 2 2 2 1 Tho1/MOS11 C-terminal domain HeH PF12949.7 KKF95834.1 - 0.0017 18.0 0.1 0.0034 17.0 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Mitofilin PF09731.9 KKF95834.1 - 1.1 8.0 15.1 1.3 7.8 15.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LPD30 PF18850.1 KKF95835.1 - 0.16 11.7 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 Utp12 PF04003.12 KKF95836.1 - 2.3e-22 79.3 0.2 2.3e-22 79.3 0.2 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family CDC45 PF02724.14 KKF95836.1 - 0.018 13.4 24.7 0.081 11.2 0.6 2.2 2 0 0 2 2 2 0 CDC45-like protein BUD22 PF09073.10 KKF95836.1 - 0.14 11.5 36.2 0.02 14.3 21.4 2.1 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KKF95836.1 - 0.25 9.5 37.1 0.049 11.9 26.3 2.2 2 0 0 2 2 2 0 Nop14-like family PsbW PF07123.12 KKF95836.1 - 0.4 10.7 4.1 0.2 11.7 0.8 2.1 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Peptidase_S8 PF00082.22 KKF95839.1 - 1.3e-46 159.2 0.0 3.2e-46 157.9 0.0 1.6 1 1 0 1 1 1 1 Subtilase family MDD_C PF18376.1 KKF95840.1 - 1.3e-61 207.6 0.1 1.8e-61 207.2 0.1 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KKF95840.1 - 1.2e-08 35.0 0.7 1.2e-08 35.0 0.7 2.3 3 0 0 3 3 3 1 GHMP kinases N terminal domain Rtf2 PF04641.12 KKF95840.1 - 0.099 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF647 PF04884.14 KKF95841.1 - 2.7e-92 308.8 4.3 3.8e-92 308.3 4.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF3687 PF12459.8 KKF95841.1 - 0.1 12.1 0.2 0.24 11.0 0.2 1.5 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Cyto_heme_lyase PF01265.17 KKF95842.1 - 1.9e-45 155.7 7.8 9.1e-44 150.2 7.8 2.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Acetyltransf_8 PF13523.6 KKF95842.1 - 1.5e-37 128.5 0.1 2.6e-37 127.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cofilin_ADF PF00241.20 KKF95843.1 - 1.8e-22 79.4 0.0 2e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RF3_C PF16658.5 KKF95843.1 - 0.061 13.2 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain PHO4 PF01384.20 KKF95844.1 - 4.2e-97 325.2 14.1 4.9e-97 325.0 14.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.16 KKF95846.1 - 5e-16 58.6 47.3 3.4e-11 42.7 13.2 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily Popeye PF04831.13 KKF95846.1 - 3.6 7.8 5.0 3.3 7.9 2.7 2.1 2 0 0 2 2 2 0 Popeye protein conserved region RRM_1 PF00076.22 KKF95848.1 - 2.1e-07 30.6 0.0 6.1e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKF95848.1 - 9.8e-05 21.9 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LIF_OSM PF01291.17 KKF95848.1 - 0.18 11.9 1.1 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 LIF / OSM family WD40 PF00400.32 KKF95849.1 - 1.6e-16 60.4 12.0 0.001 19.9 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF95849.1 - 6e-07 29.7 0.0 0.055 13.8 0.0 4.3 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ribonuc_L-PSP PF01042.21 KKF95850.1 - 1.2e-39 135.1 0.0 1.5e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1187 PF06688.11 KKF95850.1 - 0.11 12.8 0.2 0.24 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1187) AAA PF00004.29 KKF95851.1 - 2.7e-15 57.0 0.0 4.3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KKF95851.1 - 3.4e-13 50.0 0.0 4.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 KKF95851.1 - 0.00085 19.7 0.0 0.0024 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KKF95851.1 - 0.0021 18.6 0.0 0.0031 18.0 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KKF95851.1 - 0.003 17.3 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RuvB_N PF05496.12 KKF95851.1 - 0.0041 16.9 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KKF95851.1 - 0.0069 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 KKF95851.1 - 0.01 15.5 0.0 0.037 13.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKF95851.1 - 0.01 16.2 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KKF95851.1 - 0.017 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KKF95851.1 - 0.018 15.6 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKF95851.1 - 0.019 14.9 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKF95851.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKF95851.1 - 0.031 14.0 0.0 0.09 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKF95851.1 - 0.036 14.2 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KKF95851.1 - 0.037 14.5 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KKF95851.1 - 0.037 13.8 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KKF95851.1 - 0.055 13.6 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATPase PF06745.13 KKF95851.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 KKF95851.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain PPV_E1_C PF00519.17 KKF95851.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase RsgA_GTPase PF03193.16 KKF95851.1 - 0.17 11.8 0.0 0.47 10.4 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase Ribosomal_L1 PF00687.21 KKF95852.1 - 8.7e-24 84.4 0.0 1.4e-23 83.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.21 KKF95853.1 - 1.1e-100 336.6 0.0 1.4e-100 336.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KKF95853.1 - 2.4e-35 122.0 0.1 4.1e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KKF95853.1 - 0.018 14.4 0.4 0.058 12.7 0.4 1.7 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Cu-oxidase_2 PF07731.14 KKF95854.1 - 1.2e-47 161.1 7.2 5.7e-41 139.5 0.2 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KKF95854.1 - 1.5e-39 134.7 1.6 2.1e-37 127.8 0.2 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KKF95854.1 - 3.1e-34 118.4 0.4 3.6e-31 108.4 0.1 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.6 KKF95854.1 - 0.0028 17.7 0.0 1.7 8.8 0.0 3.7 4 0 0 4 4 4 1 Cupredoxin-like domain FTR1 PF03239.14 KKF95855.1 - 2.1e-78 263.6 12.5 2.5e-78 263.3 12.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Ac110_PIF PF07280.11 KKF95855.1 - 0.34 10.7 0.2 0.34 10.7 0.2 2.4 3 0 0 3 3 3 0 Per os infectivity factor AC110 DUF2207 PF09972.9 KKF95855.1 - 0.39 9.4 4.9 2.9 6.6 0.8 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1218 PF06749.12 KKF95855.1 - 1.5 9.4 9.1 0.55 10.8 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) HAT_KAT11 PF08214.11 KKF95856.1 - 6e-93 311.9 0.0 7.8e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein DUF410 PF04190.13 KKF95857.1 - 1.9e-82 276.9 0.0 2.5e-82 276.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Ribonucleas_3_3 PF14622.6 KKF95857.1 - 4.6e-10 39.8 0.0 9.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like cwf18 PF08315.12 KKF95858.1 - 0.14 12.8 1.7 0.14 12.8 0.2 1.8 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor Glycos_transf_4 PF00953.21 KKF95858.1 - 0.18 11.8 0.1 0.27 11.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 Suf PF05843.14 KKF95859.1 - 0.57 10.1 12.9 1.1 9.2 12.9 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1387 PF07139.11 KKF95859.1 - 5.8 6.6 14.3 9.9 5.8 14.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) phiKZ_IP PF12699.7 KKF95861.1 - 0.026 13.7 0.1 0.038 13.1 0.1 1.3 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins IBR PF01485.21 KKF95861.1 - 0.041 14.1 0.2 0.098 12.9 0.2 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain FOXP-CC PF16159.5 KKF95861.1 - 0.054 14.1 3.4 7.1 7.3 0.2 3.1 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KKF95861.1 - 0.079 13.5 0.0 0.079 13.5 0.0 3.6 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKF95861.1 - 1.5 9.9 8.6 4.1 8.5 0.0 3.5 3 3 0 3 3 3 0 C2H2-type zinc finger Kelch_3 PF13415.6 KKF95862.1 - 2.7e-20 72.2 10.2 7.3e-05 22.9 0.1 7.8 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KKF95862.1 - 1.8e-18 66.1 1.0 1.7e-05 24.9 0.0 6.3 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.25 KKF95862.1 - 6.2e-15 54.5 2.3 2.3e-06 27.1 0.1 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KKF95862.1 - 8e-13 48.2 15.4 0.00028 20.8 0.2 7.3 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KKF95862.1 - 7.3e-12 45.0 4.7 0.0003 20.7 0.0 6.6 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 KKF95862.1 - 1.5e-08 34.2 11.6 0.00028 20.7 0.5 5.8 6 1 0 6 6 6 3 Kelch motif 2Fe-2S_thioredx PF01257.19 KKF95863.1 - 6.3e-57 191.5 0.0 8e-57 191.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin CDC50 PF03381.15 KKF95864.1 - 1e-100 336.9 0.9 1.2e-100 336.6 0.9 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 KKF95864.1 - 0.066 13.2 1.3 2.6 8.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Rib PF08428.10 KKF95864.1 - 0.15 12.0 0.4 24 5.0 0.0 2.8 3 0 0 3 3 3 0 Rib/alpha-like repeat FACT-Spt16_Nlob PF14826.6 KKF95865.1 - 4.7e-56 189.1 0.4 4.7e-56 189.1 0.4 2.6 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 KKF95865.1 - 1.3e-54 184.4 0.3 1.3e-54 184.4 0.3 3.2 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KKF95865.1 - 2.8e-29 102.3 0.0 5.3e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KKF95865.1 - 4.4e-17 62.3 0.3 1.7e-16 60.4 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 KKF95865.1 - 0.23 11.7 0.0 0.48 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) CMD PF02627.20 KKF95866.1 - 1.8e-09 37.5 0.1 4.8e-09 36.2 0.1 1.7 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family PRMT5_C PF17286.2 KKF95866.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain CRISPR_Cse2 PF09485.10 KKF95867.1 - 0.044 14.3 1.6 2.6 8.6 0.3 2.3 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Cast PF10174.9 KKF95867.1 - 0.056 11.7 0.0 0.065 11.5 0.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone SLATT_1 PF18181.1 KKF95867.1 - 0.2 11.6 3.2 1.7 8.6 0.4 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 APH PF01636.23 KKF95868.1 - 2.5e-09 37.4 0.0 1.5e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKF95868.1 - 3.4e-09 36.4 0.0 1.4e-06 27.8 0.0 2.3 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KKF95868.1 - 9.8e-08 31.7 0.0 1.6e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KKF95868.1 - 3.4e-05 23.5 0.0 0.18 11.4 0.0 2.4 1 1 1 2 2 2 2 RIO1 family Pkinase_Tyr PF07714.17 KKF95868.1 - 0.00029 20.2 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.20 KKF95868.1 - 0.00091 18.6 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_fungal PF17667.1 KKF95868.1 - 0.0012 17.7 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase XylR_N PF06505.11 KKF95868.1 - 0.056 13.2 0.1 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Activator of aromatic catabolism Choline_kinase PF01633.20 KKF95868.1 - 0.074 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 KKF95868.1 - 0.089 11.6 0.0 0.13 11.1 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Aldo_ket_red PF00248.21 KKF95869.1 - 8.6e-09 35.0 0.0 1.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 KKF95870.1 - 1.3e-52 177.5 2.2 1.6e-52 177.3 2.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KKF95870.1 - 0.019 15.7 0.4 0.036 14.8 0.3 1.5 1 1 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 KKF95871.1 - 9.5e-53 178.9 0.0 1.2e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Response_reg PF00072.24 KKF95872.1 - 3.2e-27 94.9 0.4 6.2e-27 94.0 0.4 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KKF95872.1 - 5.1e-26 91.4 0.1 4e-19 69.2 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKF95872.1 - 2.2e-13 50.0 0.0 5.7e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KKF95872.1 - 0.0056 17.0 0.1 0.1 13.0 0.0 2.4 2 0 0 2 2 2 1 HAMP domain Med1 PF10744.9 KKF95873.1 - 2.2e-81 274.1 0.0 2.7e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.25 KKF95874.1 - 2.4e-42 145.1 0.0 8.5e-41 140.1 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95874.1 - 3.5e-25 88.8 0.0 1.9e-24 86.4 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase GPI2 PF06432.11 KKF95874.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase SAGA-Tad1 PF12767.7 KKF95875.1 - 8e-57 192.7 0.0 1.1e-56 192.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit GCP_C_terminal PF04130.13 KKF95876.1 - 4e-93 312.3 0.0 7e-93 311.5 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KKF95876.1 - 8.2e-79 265.4 0.0 1.3e-78 264.7 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Borrelia_P83 PF05262.11 KKF95876.1 - 0.07 11.6 0.2 0.1 11.1 0.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ATP-synt_E PF05680.12 KKF95876.1 - 0.59 10.5 5.9 1.3 9.4 5.9 1.5 1 0 0 1 1 1 0 ATP synthase E chain DNA_primase_lrg PF04104.14 KKF95877.1 - 2.3e-84 283.0 0.0 3.2e-84 282.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Leu_zip PF15294.6 KKF95878.1 - 7.5 6.0 18.6 0.02 14.4 6.1 2.4 3 0 0 3 3 3 0 Leucine zipper SAICAR_synt PF01259.18 KKF95879.1 - 2.2e-99 332.2 0.0 2.6e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase bVLRF1 PF18826.1 KKF95880.1 - 2e-62 209.5 0.0 2e-62 209.5 0.0 1.8 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KKF95880.1 - 4.4e-05 23.7 0.3 0.00024 21.3 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KKF95880.1 - 0.068 13.6 0.3 0.18 12.3 0.3 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 KKF95880.1 - 0.11 13.1 0.0 0.3 11.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) CCDC53 PF10152.9 KKF95880.1 - 0.8 10.1 4.0 4.5 7.7 0.2 2.5 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex CFEM PF05730.11 KKF95881.1 - 1.4e-06 28.3 1.2 1.4e-06 28.3 1.2 2.7 2 0 0 2 2 2 1 CFEM domain 3Beta_HSD PF01073.19 KKF95883.1 - 4.8e-63 212.8 0.0 5.7e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKF95883.1 - 1.4e-30 106.5 0.2 2e-30 106.0 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKF95883.1 - 2.7e-15 56.6 0.0 9.5e-14 51.5 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKF95883.1 - 5.2e-15 55.3 0.1 6.4e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KKF95883.1 - 8.2e-12 44.8 0.5 3.3e-08 33.0 0.2 2.3 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KKF95883.1 - 1.2e-11 44.8 0.1 1.8e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KKF95883.1 - 1.2e-06 27.9 2.6 6e-06 25.6 1.9 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KKF95883.1 - 0.011 15.7 2.5 0.088 12.7 2.5 2.2 1 1 0 1 1 1 0 KR domain RhoGAP PF00620.27 KKF95884.1 - 7.4e-37 126.5 0.0 1.7e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KKF95884.1 - 0.0034 17.6 23.3 0.086 13.1 0.9 4.1 4 0 0 4 4 4 3 LIM domain SURF4 PF02077.15 KKF95885.1 - 5.6e-95 317.9 11.7 7.5e-95 317.5 11.7 1.1 1 0 0 1 1 1 1 SURF4 family LETM1 PF07766.13 KKF95885.1 - 1.8e-09 37.4 1.5 2.7e-09 36.8 0.1 1.8 2 0 0 2 2 2 1 LETM1-like protein UPF0139 PF03669.13 KKF95885.1 - 1.7 8.6 3.7 5.1 7.0 3.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0139) ORMDL PF04061.14 KKF95886.1 - 1.6e-56 189.8 4.7 2e-56 189.6 4.7 1.1 1 0 0 1 1 1 1 ORMDL family cNMP_binding PF00027.29 KKF95887.1 - 7.8e-40 134.9 0.0 1.2e-20 73.3 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BCAS2 PF05700.11 KKF95888.1 - 7.6e-53 179.3 3.7 8.4e-53 179.1 3.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF3717 PF12512.8 KKF95888.1 - 0.00045 20.0 0.2 0.0013 18.5 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3717) HABP4_PAI-RBP1 PF04774.15 KKF95889.1 - 0.034 15.0 1.4 0.063 14.1 1.4 1.5 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family bZIP_1 PF00170.21 KKF95890.1 - 5.4e-06 26.4 6.0 1.1e-05 25.4 6.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKF95890.1 - 0.003 17.6 7.0 0.0052 16.8 7.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper SHE3 PF17078.5 KKF95890.1 - 0.03 14.0 0.3 0.043 13.5 0.3 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 KKF95890.1 - 0.095 13.2 6.8 0.17 12.4 6.8 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor UPF0172 PF03665.13 KKF95890.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Bacteroid_pep PF14406.6 KKF95890.1 - 0.15 12.5 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes Pox_A_type_inc PF04508.12 KKF95890.1 - 0.96 9.4 3.0 2 8.4 3.0 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Cyt-b5 PF00173.28 KKF95892.1 - 1.4e-12 47.5 0.1 1.8e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HRXXH PF13933.6 KKF95893.1 - 3.1e-99 331.5 0.1 3.6e-99 331.3 0.1 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KKF95893.1 - 0.00017 22.2 0.1 0.00037 21.1 0.1 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Dis3l2_C_term PF17877.1 KKF95893.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal HECT PF00632.25 KKF95894.1 - 1.1e-75 254.9 0.0 1.5e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RRM_1 PF00076.22 KKF95895.1 - 1e-79 262.3 7.8 1.7e-19 69.4 0.6 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KKF95895.1 - 1.4e-25 89.2 4.2 2.1e-25 88.7 2.1 2.4 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KKF95895.1 - 7.8e-10 38.4 0.2 0.0023 17.5 0.0 4.8 2 1 3 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKF95895.1 - 7.3e-08 32.4 0.9 0.7 10.0 0.0 5.6 5 1 0 5 5 5 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KKF95895.1 - 4.3e-05 23.4 0.2 9.4 6.3 0.0 4.9 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KKF95895.1 - 0.00016 21.5 0.0 0.96 9.4 0.0 3.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif CbiG_mid PF11761.8 KKF95895.1 - 0.0039 17.3 0.0 23 5.2 0.0 3.6 3 0 0 3 3 3 0 Cobalamin biosynthesis central region OB_RNB PF08206.11 KKF95895.1 - 0.026 14.2 0.6 35 4.2 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.8 KKF95895.1 - 0.027 15.0 8.0 0.33 11.5 4.4 3.3 3 1 0 3 3 3 0 Heat induced stress protein YflT SLED PF12140.8 KKF95895.1 - 0.036 14.6 0.1 0.19 12.2 0.1 2.2 1 0 0 1 1 1 0 SLED domain DUF2817 PF10994.8 KKF95895.1 - 0.058 12.8 1.5 0.12 11.7 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) PhetRS_B1 PF18262.1 KKF95895.1 - 1.5 9.1 4.3 25 5.2 0.0 3.4 3 1 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain Noggin PF05806.12 KKF95895.1 - 2.4 8.0 5.1 2.4 8.0 3.5 1.7 1 1 1 2 2 2 0 Noggin TRIQK PF15168.6 KKF95896.1 - 0.14 12.1 0.5 0.27 11.1 0.5 1.4 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family CENP-H PF05837.12 KKF95896.1 - 0.56 10.6 4.0 1.3 9.5 0.7 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ETF_QO PF05187.13 KKF95897.1 - 1.3e-47 160.3 0.3 2e-47 159.6 0.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_7 PF12838.7 KKF95897.1 - 0.011 16.3 1.0 0.028 15.0 1.0 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain NAD_binding_8 PF13450.6 KKF95897.1 - 0.066 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Fer4_2 PF12797.7 KKF95897.1 - 0.1 12.8 0.6 0.28 11.4 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain tRNA-synt_1g PF09334.11 KKF95898.1 - 5.3e-140 466.6 3.8 6.5e-138 459.7 3.8 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KKF95898.1 - 0.013 15.5 0.2 0.031 14.2 0.2 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Metallophos PF00149.28 KKF95899.1 - 1.3e-36 127.1 0.1 1.9e-36 126.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KKF95899.1 - 2.4e-15 56.7 0.0 4.4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Kelch_1 PF01344.25 KKF95900.1 - 7.6e-33 111.8 13.2 1.9e-06 27.4 0.2 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KKF95900.1 - 1e-29 101.8 10.4 6.6e-07 29.4 0.0 5.2 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.6 KKF95900.1 - 1.1e-29 101.8 11.9 1.8e-05 24.6 0.0 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 KKF95900.1 - 1.3e-29 101.9 8.6 1.7e-06 28.2 0.1 5.2 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KKF95900.1 - 1.1e-28 99.0 12.3 3.2e-06 27.1 0.4 5.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KKF95900.1 - 3.1e-23 80.8 10.6 0.00026 20.8 0.0 5.2 5 0 0 5 5 5 5 Kelch motif CCDC85 PF10226.9 KKF95901.1 - 0.037 13.7 1.5 0.078 12.6 1.5 1.5 1 0 0 1 1 1 0 CCDC85 family DUF4241 PF14025.6 KKF95901.1 - 0.062 13.6 1.0 0.1 12.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Amidase PF01425.21 KKF95902.1 - 1.5e-21 76.9 0.0 8.3e-12 44.8 0.0 2.3 1 1 1 2 2 2 2 Amidase PIG-P PF08510.12 KKF95903.1 - 5.4e-48 161.9 3.8 7.6e-48 161.4 3.8 1.2 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KKF95903.1 - 0.0022 18.2 8.2 0.0036 17.6 8.2 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Dus PF01207.17 KKF95905.1 - 1.4e-37 129.5 0.0 1.7e-27 96.3 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 KKF95905.1 - 0.0057 16.5 4.4 0.05 13.5 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KKF95905.1 - 1 9.5 4.4 12 6.1 0.5 2.5 2 0 0 2 2 2 0 Zinc finger domain AAA_23 PF13476.6 KKF95906.1 - 7e-35 121.3 0.7 7e-35 121.3 0.7 7.7 1 1 2 3 3 1 1 AAA domain AAA_15 PF13175.6 KKF95906.1 - 1.4e-14 54.6 3.0 9.2e-10 38.8 0.0 4.7 1 1 1 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 KKF95906.1 - 2.1e-12 47.5 0.4 4.2e-05 23.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKF95906.1 - 8.1e-08 32.0 0.1 8.1e-08 32.0 0.1 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KKF95906.1 - 2.6e-06 27.6 0.0 9.6e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KKF95906.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KKF95906.1 - 0.051 14.0 0.0 0.051 14.0 0.0 4.8 3 2 0 3 3 1 0 AAA ATPase domain ABC_tran PF00005.27 KKF95906.1 - 0.09 13.3 0.0 0.09 13.3 0.0 6.9 4 2 0 4 4 3 0 ABC transporter AAA_13 PF13166.6 KKF95906.1 - 0.12 11.0 0.0 0.12 11.0 0.0 7.7 2 1 5 7 7 6 0 AAA domain LPP PF04728.13 KKF95906.1 - 0.18 12.2 0.1 0.18 12.2 0.1 7.7 7 1 1 8 8 8 0 Lipoprotein leucine-zipper DUF465 PF04325.13 KKF95906.1 - 0.19 11.8 0.0 0.19 11.8 0.0 7.1 6 1 1 7 7 7 0 Protein of unknown function (DUF465) AAA_22 PF13401.6 KKF95906.1 - 0.21 11.8 0.0 0.21 11.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain Hormone_3 PF00159.18 KKF95906.1 - 0.47 10.6 1.6 9.3 6.4 0.1 3.3 3 0 0 3 3 3 0 Pancreatic hormone peptide IKKbetaNEMObind PF12179.8 KKF95906.1 - 10 6.3 7.6 22 5.2 0.1 4.3 5 0 0 5 5 4 0 I-kappa-kinase-beta NEMO binding domain GATA PF00320.27 KKF95907.1 - 1.4e-14 53.4 6.5 3.6e-14 52.1 6.5 1.8 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KKF95907.1 - 7.5e-06 26.1 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KKF95907.1 - 0.0095 16.1 0.0 0.035 14.2 0.0 1.9 2 0 0 2 2 2 1 PAS domain SR-25 PF10500.9 KKF95907.1 - 0.097 12.3 13.1 0.18 11.4 6.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Zn_ribbon_2 PF12674.7 KKF95907.1 - 0.12 13.1 0.5 22 5.8 0.1 2.4 2 0 0 2 2 2 0 Putative zinc ribbon domain DUF2197 PF09963.9 KKF95907.1 - 0.18 12.1 3.0 0.21 11.9 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) IMUP PF15761.5 KKF95907.1 - 9.1 7.0 14.6 1.1 9.9 5.4 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein PhoD PF09423.10 KKF95908.1 - 0.0001 21.5 0.0 0.0005 19.2 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.22 KKF95909.1 - 4.7e-35 121.3 0.7 7.4e-35 120.6 0.7 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KKF95909.1 - 6.7e-25 86.9 0.3 1.5e-24 85.9 0.3 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KKF95909.1 - 0.034 14.9 0.1 0.089 13.6 0.1 1.7 1 0 0 1 1 1 0 Peptidase S8 pro-domain Mucin PF01456.17 KKF95909.1 - 6.3 6.8 11.8 11 6.0 11.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PX PF00787.24 KKF95910.1 - 5.3e-20 71.5 0.4 3e-19 69.1 0.2 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KKF95910.1 - 3.3e-09 36.7 6.3 2.3e-06 27.3 0.3 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Sec34 PF04136.15 KKF95910.1 - 0.016 15.1 0.1 0.038 13.9 0.1 1.7 1 0 0 1 1 1 0 Sec34-like family COMMD1_N PF17221.3 KKF95910.1 - 0.018 15.3 0.2 2 8.8 0.0 2.9 3 0 0 3 3 3 0 COMMD1 N-terminal domain P-mevalo_kinase PF04275.14 KKF95910.1 - 0.2 11.6 1.7 0.41 10.6 0.1 2.4 2 1 1 3 3 3 0 Phosphomevalonate kinase DUF713 PF05218.14 KKF95910.1 - 0.24 11.1 3.8 1 9.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF713) DUF1664 PF07889.12 KKF95910.1 - 0.69 10.0 4.6 20 5.2 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KKF95910.1 - 4 8.0 11.7 0.54 10.8 0.8 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region LETM1 PF07766.13 KKF95911.1 - 1e-99 333.2 0.1 1.7e-99 332.6 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein Kinesin_assoc PF16183.5 KKF95911.1 - 1.4 9.0 6.3 0.22 11.7 1.5 2.0 2 0 0 2 2 2 0 Kinesin-associated ADK PF00406.22 KKF95912.1 - 4.9e-34 117.6 0.0 6.5e-18 65.3 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KKF95912.1 - 1.4e-13 50.5 0.0 2.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KKF95912.1 - 3.5e-12 46.9 0.0 3.1e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KKF95912.1 - 0.00048 20.7 0.0 0.04 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKF95912.1 - 0.0022 18.2 0.0 0.0067 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KKF95912.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CTD PF12815.7 KKF95913.1 - 1.6e-24 86.3 38.0 2.5e-18 66.4 20.1 4.4 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.13 KKF95913.1 - 1.6e-23 82.4 0.1 2.7e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KKF95913.1 - 4.2e-20 72.6 10.6 4.2e-20 72.6 10.6 3.4 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KKF95913.1 - 1.2e-08 34.6 22.0 0.00074 19.4 2.7 4.9 4 0 0 4 4 4 3 KOW motif DUF3912 PF13051.6 KKF95913.1 - 0.0087 16.3 0.7 0.13 12.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) Cornifin PF02389.15 KKF95913.1 - 0.041 14.1 2.4 0.097 12.9 2.4 1.5 1 0 0 1 1 1 0 Cornifin (SPRR) family WD40 PF00400.32 KKF95914.1 - 5.4e-07 30.2 4.0 0.095 13.6 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat DPBB_1 PF03330.18 KKF95915.1 - 0.044 14.1 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 Lytic transglycolase BAT PF15915.5 KKF95915.1 - 0.06 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 GAF and HTH_10 associated domain TFIIA PF03153.13 KKF95915.1 - 4.9 7.0 6.4 6.2 6.7 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 KKF95915.1 - 7.7 5.6 11.6 9.8 5.2 11.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PP2C PF00481.21 KKF95916.1 - 8.6e-82 274.6 0.0 1.3e-81 274.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PPR_2 PF13041.6 KKF95917.1 - 0.0031 17.7 0.0 0.28 11.4 0.0 2.9 2 1 1 3 3 3 1 PPR repeat family PPR_3 PF13812.6 KKF95917.1 - 0.063 13.4 0.0 0.71 10.0 0.0 2.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain KH_1 PF00013.29 KKF95917.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 KH domain DUF4476 PF14771.6 KKF95918.1 - 0.00015 22.0 0.3 0.00028 21.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) CheZ PF04344.13 KKF95918.1 - 0.0035 17.3 0.2 0.0047 16.9 0.2 1.2 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ Spc7 PF08317.11 KKF95918.1 - 0.12 11.2 3.5 0.33 9.8 3.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein KAR9 PF08580.10 KKF95918.1 - 0.14 10.7 0.7 0.17 10.4 0.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Microvir_H PF04687.12 KKF95919.1 - 0.0065 15.9 2.3 0.0075 15.7 2.3 1.0 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) Apolipoprotein PF01442.18 KKF95919.1 - 0.014 15.3 1.5 0.021 14.7 1.5 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain E2F_CC-MB PF16421.5 KKF95919.1 - 0.049 14.0 0.1 0.071 13.5 0.1 1.2 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain DUF883 PF05957.13 KKF95919.1 - 0.062 13.9 3.4 0.094 13.3 3.2 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 KKF95919.1 - 0.081 10.9 0.1 0.085 10.8 0.1 1.1 1 0 0 1 1 1 0 Prominin Phage_holin_7_1 PF16081.5 KKF95919.1 - 0.087 13.0 5.8 0.078 13.2 4.7 1.5 1 1 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family V-SNARE PF05008.15 KKF95919.1 - 0.1 13.0 0.4 0.12 12.7 0.4 1.2 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus ATP-synt_B PF00430.18 KKF95919.1 - 0.12 12.5 9.7 0.62 10.1 4.7 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF1664 PF07889.12 KKF95919.1 - 1 9.4 4.4 0.49 10.4 1.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ETRAMP PF09716.10 KKF95919.1 - 4.8 7.3 7.9 22 5.2 2.8 2.7 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4407 PF14362.6 KKF95920.1 - 0.25 10.6 4.0 0.44 9.8 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L16 PF00252.18 KKF95921.1 - 1.2e-45 154.7 0.1 1.6e-45 154.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.26 KKF95922.1 - 9.3e-25 86.2 0.0 1.1e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3818 PF12825.7 KKF95923.1 - 0.75 8.8 6.2 1.5 7.7 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Fmp27_WPPW PF10359.9 KKF95923.1 - 2 7.2 16.3 1.9 7.2 11.8 2.3 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain GAS PF13851.6 KKF95923.1 - 2.1 7.7 34.7 0.2 11.0 17.8 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Host_attach PF10116.9 KKF95923.1 - 3 8.4 13.5 5 7.7 8.2 3.0 2 1 0 2 2 2 0 Protein required for attachment to host cells DUF489 PF04356.12 KKF95923.1 - 3.7 7.5 8.3 1.1 9.2 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Fib_alpha PF08702.10 KKF95923.1 - 5.9 7.1 15.5 2.1 8.5 7.9 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AA_permease PF00324.21 KKF95924.1 - 9.8e-132 439.9 43.5 1.2e-131 439.6 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKF95924.1 - 6.3e-33 114.2 50.7 1.2e-32 113.3 50.8 1.4 1 1 0 1 1 1 1 Amino acid permease AAA_12 PF13087.6 KKF95925.1 - 4.4e-20 72.1 0.0 9.4e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKF95925.1 - 1.1e-09 38.5 0.0 2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF95925.1 - 3.7e-07 30.6 0.0 7.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKF95925.1 - 6.4e-07 29.3 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KKF95925.1 - 0.00011 21.6 0.1 0.001 18.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KKF95925.1 - 0.00089 18.7 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.17 KKF95925.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KKF95925.1 - 0.026 14.1 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KKF95925.1 - 0.028 14.4 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KKF95925.1 - 0.029 14.1 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 KKF95925.1 - 0.038 13.7 0.0 0.38 10.4 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KKF95925.1 - 0.056 13.3 0.1 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Helicase AAA_10 PF12846.7 KKF95925.1 - 0.069 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 KKF95925.1 - 0.1 12.9 0.0 0.4 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKF95925.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Cu-oxidase_3 PF07732.15 KKF95926.1 - 1.2e-39 135.0 1.1 1.2e-39 135.0 1.1 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KKF95926.1 - 8.9e-33 113.7 0.1 3.5e-30 105.2 0.0 3.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKF95926.1 - 1.7e-32 112.0 11.8 5.8e-31 107.1 1.4 3.4 3 1 0 3 3 3 2 Multicopper oxidase BAR PF03114.18 KKF95927.1 - 4.6e-11 42.8 1.2 6.4e-11 42.4 1.2 1.2 1 0 0 1 1 1 1 BAR domain Bot1p PF12298.8 KKF95928.1 - 5.4e-46 156.9 3.6 7.9e-46 156.4 3.6 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Response_reg PF00072.24 KKF95929.1 - 6.7e-23 81.0 0.0 1.4e-15 57.4 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain Acetyltransf_1 PF00583.25 KKF95930.1 - 4.2e-11 43.1 0.1 5.4e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKF95930.1 - 1.5e-08 35.0 0.2 2.2e-08 34.4 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKF95930.1 - 1.7e-07 31.2 0.1 2.5e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 KKF95930.1 - 0.022 13.3 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Peptidase_S9 PF00326.21 KKF95931.1 - 4e-07 29.7 0.3 1.4e-06 28.0 0.3 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1100 PF06500.11 KKF95931.1 - 1.1e-06 27.8 0.0 2.2e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.8 KKF95931.1 - 2.4e-05 23.7 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KKF95931.1 - 2.8e-05 23.9 0.0 9.2e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 KKF95931.1 - 0.00046 19.9 0.3 0.0016 18.1 0.3 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KKF95931.1 - 0.0082 16.8 1.2 0.0082 16.8 1.2 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KKF95931.1 - 0.024 14.2 0.0 0.83 9.2 0.0 2.3 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KKF95931.1 - 0.05 13.4 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 KKF95931.1 - 0.055 13.0 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 KKF95931.1 - 0.088 12.4 0.2 5.3 6.6 0.3 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold SNARE PF05739.19 KKF95932.1 - 1.1e-12 47.8 0.1 1.1e-12 47.8 0.1 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 KKF95932.1 - 5.8e-09 34.9 2.1 5.8e-09 34.9 2.1 2.5 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KKF95932.1 - 1.9e-05 24.4 0.1 1.9e-05 24.4 0.1 2.9 2 1 2 4 4 4 1 Syntaxin KxDL PF10241.9 KKF95932.1 - 0.0076 16.5 5.6 0.24 11.7 0.1 3.6 4 0 0 4 4 4 2 Uncharacterized conserved protein DUF4988 PF16378.5 KKF95932.1 - 0.054 13.2 2.3 14 5.3 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function Syntaxin-18_N PF10496.9 KKF95932.1 - 0.089 13.1 0.2 0.24 11.7 0.2 1.8 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus ACPS PF01648.20 KKF95933.1 - 2.1e-11 44.0 0.0 3.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily HTH_43 PF09904.9 KKF95933.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Peptidase_A22B PF04258.13 KKF95934.1 - 1.2e-33 116.8 3.4 9.9e-17 61.4 0.1 3.1 3 0 0 3 3 3 3 Signal peptide peptidase Pro_isomerase PF00160.21 KKF95935.1 - 3.5e-51 173.6 0.0 3.9e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf_UBZ PF18439.1 KKF95936.1 - 0.77 9.4 2.5 2.3 7.9 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 KKF95936.1 - 0.78 9.4 7.2 0.1 12.2 2.0 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Hexokinase_1 PF00349.21 KKF95937.1 - 1e-74 250.8 0.2 1.3e-74 250.4 0.2 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KKF95937.1 - 1.9e-74 250.2 0.0 4.5e-74 248.9 0.0 1.6 2 0 0 2 2 2 1 Hexokinase HSP70 PF00012.20 KKF95938.1 - 3.2e-09 35.5 0.1 4.5e-09 35.1 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKF95938.1 - 0.085 11.7 0.0 0.29 9.9 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Ank_2 PF12796.7 KKF95939.1 - 3.9e-09 37.0 0.1 1.1e-08 35.6 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKF95939.1 - 6.8e-09 36.1 0.0 6e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKF95939.1 - 8.7e-09 34.9 0.4 0.029 14.9 0.0 3.9 3 1 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KKF95939.1 - 2.9e-07 30.6 0.4 2.6 8.5 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KKF95939.1 - 2.3e-05 24.6 0.1 0.84 10.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat ATP-sulfurylase PF01747.17 KKF95941.1 - 2.9e-89 298.1 0.1 4.4e-89 297.5 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KKF95941.1 - 1.3e-56 190.8 0.0 2e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KKF95941.1 - 3.5e-52 176.3 0.0 6e-52 175.5 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain CPT PF07931.12 KKF95941.1 - 0.037 13.9 0.2 0.2 11.5 0.2 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Pep3_Vps18 PF05131.14 KKF95942.1 - 4.7e-44 149.8 0.1 1.2e-43 148.5 0.1 1.8 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KKF95942.1 - 4.1e-08 33.2 6.7 3.5e-07 30.2 0.1 3.7 4 0 0 4 4 4 1 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 KKF95942.1 - 0.001 18.6 0.1 0.0023 17.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF2175 PF09943.9 KKF95942.1 - 0.0023 18.2 0.3 0.2 12.0 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_5 PF14634.6 KKF95942.1 - 0.0026 17.7 0.4 0.0026 17.7 0.4 1.7 2 0 0 2 2 1 1 zinc-RING finger domain Vps39_2 PF10367.9 KKF95942.1 - 0.0048 17.3 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 KKF95942.1 - 0.0072 16.1 0.8 0.017 15.0 0.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKF95942.1 - 0.03 14.6 0.6 0.084 13.2 0.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 KKF95942.1 - 0.041 14.2 0.2 0.093 13.0 0.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KKF95942.1 - 0.08 13.0 0.5 0.18 11.8 0.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PspA_IM30 PF04012.12 KKF95942.1 - 0.11 12.1 0.1 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 PspA/IM30 family DUF3105 PF11303.8 KKF95942.1 - 0.15 12.2 0.0 0.58 10.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) DUF2582 PF10771.9 KKF95942.1 - 0.15 12.2 0.0 3.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix domain (DUF2582) zf-C3HC4 PF00097.25 KKF95942.1 - 0.27 11.1 0.5 0.9 9.5 0.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KKF95942.1 - 1.2 8.9 11.2 0.041 13.6 4.4 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-C3H2C3 PF17122.5 KKF95942.1 - 6.9 6.8 5.8 1.3 9.1 1.9 1.8 2 0 0 2 2 2 0 Zinc-finger Asp PF00026.23 KKF95943.1 - 6.4e-71 239.3 10.2 8.4e-71 239.0 10.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKF95943.1 - 2.9e-11 43.9 6.4 5.4e-09 36.5 5.3 3.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKF95943.1 - 1.9e-05 25.2 2.2 0.27 11.9 0.1 4.4 3 2 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 KKF95943.1 - 4e-05 23.4 0.2 0.00012 22.0 0.2 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KKF95943.1 - 0.0012 19.4 0.3 4 8.1 0.0 4.1 3 3 1 4 4 4 1 gag-polyprotein putative aspartyl protease Lipocalin_4 PF13648.6 KKF95943.1 - 0.043 14.8 2.3 0.043 14.8 2.3 2.5 2 1 0 2 2 2 0 Lipocalin-like domain UBD PF16455.5 KKF95943.1 - 0.052 13.8 0.1 0.21 11.9 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-binding domain Pkinase PF00069.25 KKF95944.1 - 3.9e-67 226.4 0.0 6.5e-67 225.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF95944.1 - 1.6e-48 165.3 0.0 2.8e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KKF95944.1 - 7.9e-27 93.5 0.0 1.4e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KKF95944.1 - 1.4e-15 57.1 0.3 7.2e-15 54.8 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KKF95944.1 - 3.5e-15 56.2 0.1 7e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KKF95944.1 - 7.2e-14 52.2 0.0 1.3e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 KKF95944.1 - 6.9e-08 32.2 0.0 8.1e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KKF95944.1 - 0.0087 14.9 1.6 0.023 13.5 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase Relaxase PF03432.14 KKF95944.1 - 0.015 14.9 0.0 0.052 13.2 0.0 1.8 1 1 0 1 1 1 0 Relaxase/Mobilisation nuclease domain SAM_4 PF18017.1 KKF95944.1 - 0.021 14.8 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KKF95944.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Sulfotransfer_3 PF13469.6 KKF95945.1 - 2e-08 34.9 0.5 3.5e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase family UCMA PF17085.5 KKF95945.1 - 0.0015 18.6 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Unique cartilage matrix associated protein Mhr1 PF12829.7 KKF95946.1 - 1.6e-27 95.4 0.0 2.4e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination UPF0552 PF10574.9 KKF95946.1 - 0.0012 18.2 0.4 0.002 17.5 0.4 1.3 1 0 0 1 1 1 1 Arp2/3-interacting proteins Arpin AAA_2 PF07724.14 KKF95947.1 - 1e-47 162.4 0.0 8.9e-46 156.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KKF95947.1 - 3e-32 110.6 3.1 3e-32 110.6 3.1 3.8 3 1 1 4 4 3 1 AAA lid domain AAA PF00004.29 KKF95947.1 - 9.8e-27 94.0 0.1 1.4e-14 54.6 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KKF95947.1 - 1.2e-24 86.1 0.3 7.1e-24 83.7 0.3 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KKF95947.1 - 1.2e-15 57.8 0.0 1.4e-09 38.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKF95947.1 - 1.3e-12 48.2 0.0 4.7e-05 23.7 0.0 4.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKF95947.1 - 6.4e-11 42.9 14.8 4.8e-07 30.3 0.1 5.3 4 3 1 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KKF95947.1 - 2.2e-09 37.2 0.0 2e-05 24.4 0.0 3.2 2 2 1 3 3 3 2 Sigma-54 interaction domain AAA_7 PF12775.7 KKF95947.1 - 1.9e-06 27.5 0.0 0.015 14.8 0.0 2.9 2 1 1 3 3 3 2 P-loop containing dynein motor region AAA_14 PF13173.6 KKF95947.1 - 2.3e-06 27.7 0.0 0.085 12.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KKF95947.1 - 6.9e-06 25.6 0.1 0.18 11.2 0.0 3.6 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KKF95947.1 - 7.9e-06 25.7 0.0 0.094 12.4 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 KKF95947.1 - 9.7e-06 25.8 1.0 0.26 11.4 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KKF95947.1 - 1.6e-05 25.4 5.2 0.051 14.1 0.0 4.1 4 1 0 4 4 3 2 AAA domain AAA_28 PF13521.6 KKF95947.1 - 2.3e-05 24.7 0.0 0.4 10.9 0.0 3.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KKF95947.1 - 2.4e-05 24.7 0.0 0.55 10.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 KKF95947.1 - 3.8e-05 23.5 0.1 6.2 6.5 0.0 5.0 5 0 0 5 5 5 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 KKF95947.1 - 7.5e-05 21.9 1.1 0.004 16.3 0.9 3.1 2 1 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 KKF95947.1 - 8.8e-05 22.5 10.0 0.023 14.6 0.1 4.9 4 2 0 5 5 5 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KKF95947.1 - 0.00012 21.8 0.0 0.72 9.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 KKF95947.1 - 0.0002 21.4 0.0 0.3 11.1 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KKF95947.1 - 0.00023 21.1 0.0 0.019 14.9 0.0 2.8 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 KKF95947.1 - 0.00026 21.0 0.0 0.24 11.3 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase AAA_3 PF07726.11 KKF95947.1 - 0.00028 20.8 0.1 2.6 7.9 0.0 4.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KKF95947.1 - 0.0003 20.6 0.0 0.76 9.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KKF95947.1 - 0.00035 21.1 0.1 0.97 10.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter ResIII PF04851.15 KKF95947.1 - 0.00052 20.1 0.0 1.4 8.9 0.0 4.3 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit Torsin PF06309.11 KKF95947.1 - 0.0019 18.3 0.0 0.009 16.1 0.0 2.0 2 0 0 2 2 2 1 Torsin AAA_19 PF13245.6 KKF95947.1 - 0.002 18.4 2.7 0.45 10.8 0.0 4.0 5 1 1 6 6 3 1 AAA domain Sigma54_activ_2 PF14532.6 KKF95947.1 - 0.005 17.0 0.0 8.9 6.4 0.0 3.4 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_29 PF13555.6 KKF95947.1 - 0.0053 16.5 0.0 5.8 6.7 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KKF95947.1 - 0.0053 16.1 0.0 1.3 8.3 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.15 KKF95947.1 - 0.0065 16.4 0.0 0.17 11.7 0.0 3.0 3 0 0 3 3 2 1 NTPase Roc PF08477.13 KKF95947.1 - 0.0081 16.4 0.0 2.8 8.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Clp_N PF02861.20 KKF95947.1 - 0.019 15.1 7.6 0.26 11.4 0.1 4.1 4 0 0 4 4 3 0 Clp amino terminal domain, pathogenicity island component Rad17 PF03215.15 KKF95947.1 - 0.024 14.5 0.0 8.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 KKF95947.1 - 0.029 14.0 0.0 5.1 6.7 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 KKF95947.1 - 0.029 13.5 0.0 1.4 8.0 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KKF95947.1 - 0.043 13.4 4.9 0.58 9.7 0.0 3.6 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.17 KKF95947.1 - 0.051 13.4 0.0 5.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 KKF95947.1 - 0.096 12.7 1.2 12 5.9 0.0 3.4 3 2 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.9 KKF95947.1 - 0.12 12.1 0.0 7.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 KKF95947.1 - 0.31 11.5 21.2 0.38 11.2 0.0 4.6 3 1 1 4 4 2 0 AAA domain Cytidylate_kin PF02224.18 KKF95947.1 - 0.73 9.5 9.1 40 3.9 0.0 4.6 5 0 0 5 5 5 0 Cytidylate kinase V_ATPase_I PF01496.19 KKF95947.1 - 0.8 7.5 6.1 1.3 6.8 6.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_CLD_2 PF14197.6 KKF95947.1 - 1 9.5 17.4 0.038 14.1 7.5 2.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF4407 PF14362.6 KKF95947.1 - 3.7 6.8 17.5 1.1 8.5 14.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ribosomal_S13 PF00416.22 KKF95948.1 - 3.9e-56 188.9 1.9 4.6e-56 188.7 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KKF95948.1 - 0.016 14.0 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KKF95948.1 - 0.096 13.0 0.1 0.35 11.2 0.1 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif SBDS_C PF09377.10 KKF95949.1 - 7.2e-45 151.7 0.2 1.1e-44 151.1 0.2 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KKF95949.1 - 7.9e-37 125.2 0.3 1.5e-36 124.3 0.3 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF627 PF04781.12 KKF95949.1 - 0.014 15.4 0.1 0.059 13.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Auxin_repressed PF05564.12 KKF95949.1 - 0.018 15.7 1.4 0.039 14.6 1.4 1.6 1 0 0 1 1 1 0 Dormancy/auxin associated protein FliL PF03748.14 KKF95949.1 - 0.096 13.3 0.2 5.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL tRNA-synt_1b PF00579.25 KKF95950.1 - 1.5e-19 70.4 0.7 6e-19 68.5 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) FAD_syn PF06574.12 KKF95950.1 - 0.28 11.1 2.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 FAD synthetase UCH PF00443.29 KKF95951.1 - 1.5e-70 237.6 0.1 3.8e-70 236.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PDEase_I PF00233.19 KKF95951.1 - 1.2e-57 195.4 0.6 2e-57 194.7 0.6 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase UCH_1 PF13423.6 KKF95951.1 - 9.1e-12 45.2 0.0 6.4e-05 22.7 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KKF95951.1 - 5e-11 43.1 0.0 1.9e-10 41.2 0.0 2.1 1 0 0 1 1 1 1 DUSP domain TniQ PF06527.11 KKF95951.1 - 0.18 12.5 0.6 0.59 10.8 0.6 1.8 1 0 0 1 1 1 0 TniQ Peptidase_S10 PF00450.22 KKF95952.1 - 4.8e-129 431.4 0.1 6.9e-129 430.9 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase NUDIX_2 PF13869.6 KKF95952.1 - 1.7e-78 262.5 0.0 2.4e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase Carbpep_Y_N PF05388.11 KKF95952.1 - 8.7e-13 48.9 0.9 2e-12 47.8 0.9 1.6 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide UPF0047 PF01894.17 KKF95953.1 - 2.1e-16 60.1 0.0 3.9e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.9 KKF95953.1 - 8.9e-13 48.1 1.3 1.4e-12 47.4 1.3 1.3 1 0 0 1 1 1 1 Zinc-finger domain MPP6 PF10175.9 KKF95954.1 - 0.0095 16.4 14.0 0.27 11.8 13.0 2.7 1 1 1 2 2 2 1 M-phase phosphoprotein 6 COPR5 PF15340.6 KKF95954.1 - 0.012 16.3 2.4 0.012 16.3 2.4 1.7 1 1 1 2 2 2 0 Cooperator of PRMT5 family T5orf172 PF10544.9 KKF95954.1 - 0.31 11.6 1.1 3 8.4 0.2 2.5 2 1 0 2 2 2 0 T5orf172 domain SpoIIIAH PF12685.7 KKF95954.1 - 3 7.6 10.9 5.8 6.7 0.4 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Peptidase_M16_M PF16187.5 KKF95955.1 - 1.5e-88 296.8 1.5 2.4e-88 296.1 1.5 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KKF95955.1 - 1.1e-36 126.1 0.8 1.1e-34 119.6 0.1 2.6 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KKF95955.1 - 1.5e-16 60.9 0.3 8.1e-07 29.2 0.0 3.8 3 2 0 3 3 3 2 Peptidase M16 inactive domain Pet100 PF09803.9 KKF95957.1 - 4.8e-18 65.4 1.3 5.9e-18 65.2 1.3 1.1 1 0 0 1 1 1 1 Pet100 Transcrip_reg PF01709.20 KKF95958.1 - 9.8e-56 188.8 0.0 1.2e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator HEAT_EZ PF13513.6 KKF95959.1 - 0.0058 17.1 15.3 0.034 14.7 0.1 7.4 8 1 1 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KKF95959.1 - 0.0068 17.0 0.0 7.5 7.2 0.0 3.3 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 KKF95959.1 - 0.012 15.5 0.3 3.9 7.4 0.1 4.4 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central HEAT PF02985.22 KKF95959.1 - 0.036 14.3 17.4 20 5.8 0.0 8.4 10 0 0 10 10 10 0 HEAT repeat MMS19_N PF14500.6 KKF95959.1 - 0.42 10.1 2.5 30 4.1 0.0 3.6 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II Mob_synth_C PF06463.13 KKF95961.1 - 1.5e-34 118.7 0.0 1.8e-33 115.2 0.0 2.2 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KKF95961.1 - 2.3e-24 86.6 0.0 4.3e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KKF95961.1 - 0.00014 22.1 0.0 0.00036 20.8 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fungal_TACC PF12709.7 KKF95962.1 - 4.8e-10 39.7 21.6 5.2e-10 39.6 2.2 4.3 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins Shugoshin_N PF07558.11 KKF95962.1 - 0.055 13.4 0.2 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 KKF95962.1 - 0.34 11.1 52.4 0.25 11.5 18.9 4.6 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) TSC22 PF01166.18 KKF95962.1 - 0.39 11.1 7.1 0.47 10.8 0.0 3.4 3 1 0 3 3 3 0 TSC-22/dip/bun family Fez1 PF06818.15 KKF95962.1 - 1.4 9.4 42.1 0.04 14.4 13.7 3.2 1 1 2 3 3 3 0 Fez1 TACC_C PF05010.14 KKF95962.1 - 5.2 6.8 33.0 0.13 12.1 17.9 3.0 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Aldedh PF00171.22 KKF95963.1 - 3.7e-11 42.2 8.4 1.3e-08 33.8 4.8 2.7 1 1 1 2 2 2 2 Aldehyde dehydrogenase family IgG_binding_B PF01378.17 KKF95963.1 - 0.084 13.0 0.3 0.2 11.7 0.3 1.6 1 0 0 1 1 1 0 B domain PALP PF00291.25 KKF95964.1 - 3.2e-52 177.8 2.1 7.4e-52 176.6 1.1 2.1 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme IlvN PF07991.12 KKF95964.1 - 6.8e-46 155.8 0.2 6.9e-45 152.6 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KKF95964.1 - 1.6e-36 125.7 0.0 3.4e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KKF95964.1 - 0.00065 20.2 0.3 1.2 9.8 0.0 3.1 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent LSM PF01423.22 KKF95965.1 - 4.4e-18 64.7 0.1 5.6e-18 64.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KKF95965.1 - 0.0047 17.0 0.1 0.0062 16.7 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Tyrosinase PF00264.20 KKF95966.1 - 3.1e-51 174.8 6.0 4.8e-51 174.2 6.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KKF95966.1 - 2.4e-30 105.7 0.0 4e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain DUF4384 PF14326.6 KKF95966.1 - 0.067 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) RNA_pol_Rpb2_6 PF00562.28 KKF95967.1 - 1.9e-113 379.5 0.2 2.6e-113 379.0 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 KKF95967.1 - 3.7e-28 97.5 0.1 1.2e-27 95.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KKF95967.1 - 3.4e-22 79.0 0.0 6e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.15 KKF95967.1 - 1.2e-21 77.1 0.0 2.3e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.12 KKF95967.1 - 3.5e-21 74.9 0.0 7.7e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KKF95967.1 - 5.5e-14 52.3 0.0 3.1e-13 49.9 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Beta_elim_lyase PF01212.21 KKF95968.1 - 9.2e-45 153.2 0.3 1.2e-44 152.8 0.3 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Arf PF00025.21 KKF95968.1 - 1.4e-41 141.8 0.1 2.3e-41 141.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKF95968.1 - 7.7e-17 61.4 0.0 1.3e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF95968.1 - 1.8e-15 57.2 0.0 3.6e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KKF95968.1 - 3.1e-07 30.0 0.0 4.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKF95968.1 - 1.6e-06 28.2 0.0 3.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KKF95968.1 - 2.7e-05 23.5 0.0 0.00012 21.4 0.0 2.0 2 0 0 2 2 2 1 G-protein alpha subunit Aminotran_1_2 PF00155.21 KKF95968.1 - 9.3e-05 21.8 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SRPRB PF09439.10 KKF95968.1 - 0.00063 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DegT_DnrJ_EryC1 PF01041.17 KKF95968.1 - 0.0028 17.0 0.2 0.0057 16.0 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family FeoB_N PF02421.18 KKF95968.1 - 0.058 12.9 0.5 0.15 11.5 0.5 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Cys_Met_Meta_PP PF01053.20 KKF95968.1 - 0.094 11.2 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Dynamin_N PF00350.23 KKF95968.1 - 0.14 12.2 0.1 0.74 9.8 0.1 2.0 1 1 1 2 2 2 0 Dynamin family LigT_PEase PF02834.16 KKF95968.1 - 0.2 11.9 0.0 1.7 8.9 0.0 2.5 2 1 0 2 2 2 0 LigT like Phosphoesterase ABC_tran PF00005.27 KKF95968.1 - 0.23 12.0 0.5 1.5 9.3 0.5 2.4 1 1 0 1 1 1 0 ABC transporter Trehalase PF01204.18 KKF95969.1 - 5.5e-118 395.0 0.3 5.8e-117 391.6 0.3 2.0 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 KKF95969.1 - 7.8e-06 25.1 0.0 1.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Nucleoporin_FG PF13634.6 KKF95970.1 - 1.8e-07 31.9 37.9 1.3e-05 26.0 18.0 10.4 4 2 4 8 8 8 2 Nucleoporin FG repeat region NUP214 PF16755.5 KKF95970.1 - 1.3e-06 27.9 0.0 6.9e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 KKF95970.1 - 0.0014 18.9 0.0 0.011 16.0 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2353 PF09789.9 KKF95970.1 - 0.0096 15.3 4.4 0.018 14.4 4.4 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DUF1796 PF08795.10 KKF95970.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) FapA PF03961.13 KKF95970.1 - 0.092 11.3 0.9 0.16 10.5 0.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A RR_TM4-6 PF06459.12 KKF95970.1 - 9.6 5.9 10.1 63 3.3 10.1 2.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Proteasome PF00227.26 KKF95971.1 - 2.1e-47 161.1 0.1 3.1e-47 160.5 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KKF95971.1 - 6.1e-12 44.7 0.2 6.1e-12 44.7 0.2 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Sel1 PF08238.12 KKF95972.1 - 3.3e-13 49.8 8.6 0.00036 21.1 0.2 4.2 4 1 0 4 4 4 3 Sel1 repeat COPIIcoated_ERV PF07970.12 KKF95973.1 - 1.6e-86 289.7 0.1 9.1e-86 287.3 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KKF95973.1 - 1.4e-27 95.9 0.1 4.7e-27 94.2 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CSTF2_hinge PF14327.6 KKF95974.1 - 1.3e-29 102.5 0.7 2.6e-29 101.5 0.7 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KKF95974.1 - 1.4e-21 76.1 0.0 2.2e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KKF95974.1 - 6.8e-11 41.6 1.5 6.8e-11 41.6 1.5 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KKF95974.1 - 0.0022 18.0 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Dus PF01207.17 KKF95975.1 - 2.1e-37 128.9 0.0 8.7e-37 126.9 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Alpha-amylase PF00128.24 KKF95976.1 - 3.6e-55 187.9 0.2 4.9e-55 187.4 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KKF95976.1 - 2.3e-18 66.2 0.6 7.1e-18 64.7 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF3000 PF11452.8 KKF95976.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) RTBV_P12 PF06361.11 KKF95976.1 - 0.18 12.2 0.6 0.45 10.9 0.6 1.7 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein Fer2_3 PF13085.6 KKF95978.1 - 3e-32 110.8 0.0 5.2e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KKF95978.1 - 2e-08 34.6 6.7 2e-08 34.6 6.7 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKF95978.1 - 6.6e-08 32.5 3.1 6.6e-08 32.5 3.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKF95978.1 - 1.9e-07 31.4 8.8 1.9e-07 31.4 8.8 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KKF95978.1 - 2.9e-05 23.9 1.5 0.00055 19.8 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KKF95978.1 - 0.00044 20.8 3.3 0.00044 20.8 3.3 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKF95978.1 - 0.017 15.3 0.3 0.49 10.6 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKF95978.1 - 0.13 12.5 11.7 0.45 10.7 9.2 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain SpoIIE PF07228.12 KKF95979.1 - 1.2e-09 38.4 0.3 2.5e-09 37.3 0.2 1.6 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KKF95979.1 - 1.2e-05 25.0 1.1 5.3e-05 23.0 1.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KKF95979.1 - 1.3e-05 24.9 0.8 0.002 17.8 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C GPI-anchored PF10342.9 KKF95980.1 - 6.5e-12 46.0 0.5 6.5e-12 46.0 0.5 2.5 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KKF95980.1 - 0.26 10.4 15.7 0.27 10.4 15.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Tmemb_cc2 PF10267.9 KKF95980.1 - 1.3 8.1 6.1 1.6 7.8 6.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein STE2 PF02116.15 KKF95981.1 - 1.1e-38 133.2 15.9 1.9e-19 70.0 1.4 2.0 1 1 1 2 2 2 2 Fungal pheromone mating factor STE2 GPCR UEV PF05743.13 KKF95982.1 - 4.2e-37 126.7 0.7 5.9e-37 126.2 0.7 1.2 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KKF95982.1 - 1e-21 76.6 0.9 1.7e-21 75.9 0.1 1.8 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 KKF95982.1 - 0.0001 22.0 0.4 0.00017 21.2 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ADIP PF11559.8 KKF95982.1 - 0.0091 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding RWD PF05773.22 KKF95982.1 - 0.025 14.9 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF4484 PF14831.6 KKF95982.1 - 0.047 13.7 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF4515 PF14988.6 KKF95982.1 - 0.097 12.5 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) IDO PF01231.18 KKF95983.1 - 1.2e-163 545.0 0.0 1.4e-163 544.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase RNA_pol_Rpb2_6 PF00562.28 KKF95984.1 - 3.4e-110 368.8 0.7 1.1e-72 245.3 0.7 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKF95984.1 - 4.8e-51 173.2 0.0 1.1e-50 172.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KKF95984.1 - 5e-47 160.0 0.0 8.4e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KKF95984.1 - 1.3e-33 115.2 0.1 2.8e-33 114.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KKF95984.1 - 3e-25 88.2 0.1 8.1e-25 86.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KKF95984.1 - 4e-23 81.7 1.1 1.2e-22 80.2 1.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 KKF95984.1 - 2.2e-22 79.1 0.3 6e-22 77.7 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_45 PF10385.9 KKF95984.1 - 0.1 12.8 0.1 4 7.8 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain PET117 PF15786.5 KKF95985.1 - 1.5e-21 76.4 3.0 1.8e-21 76.2 3.0 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial TORC_N PF12884.7 KKF95985.1 - 0.015 16.0 1.1 0.019 15.7 1.1 1.2 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus Neur_chan_memb PF02932.16 KKF95985.1 - 0.17 12.0 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V-ATPase_G PF03179.15 KKF95986.1 - 3.2e-22 79.0 15.5 3.8e-22 78.8 15.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit PDCD7 PF16021.5 KKF95986.1 - 0.097 11.8 6.8 0.12 11.5 6.8 1.1 1 0 0 1 1 1 0 Programmed cell death protein 7 PIN_12 PF16289.5 KKF95986.1 - 0.1 13.1 2.4 0.12 12.8 2.4 1.1 1 0 0 1 1 1 0 PIN domain RRF PF01765.19 KKF95986.1 - 4.5 7.2 11.4 6.3 6.7 11.4 1.3 1 0 0 1 1 1 0 Ribosome recycling factor FlgM PF04316.13 KKF95986.1 - 7.5 7.0 14.6 1e+03 0.1 14.6 2.3 1 1 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF4407 PF14362.6 KKF95986.1 - 9.2 5.5 10.0 11 5.3 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CTNNBL PF08216.11 KKF95987.1 - 1.7e-36 124.5 0.2 1.6e-35 121.4 0.0 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Daxx PF03344.15 KKF95987.1 - 0.068 13.2 0.1 0.24 11.5 0.1 1.9 2 0 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain His_Phos_1 PF00300.22 KKF95988.1 - 7.5e-12 45.4 0.0 9.7e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SIS PF01380.22 KKF95988.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 SIS domain LepA_C PF06421.12 KKF95989.1 - 1.4e-42 144.2 2.3 2.6e-42 143.3 2.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 KKF95989.1 - 3.1e-33 115.0 0.0 5.3e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KKF95989.1 - 2.3e-21 75.6 0.0 4.5e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KKF95989.1 - 7e-06 26.1 0.0 1.9e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 KKF95989.1 - 0.00067 19.3 0.0 0.0022 17.6 0.0 1.8 2 0 0 2 2 2 1 Ras family GTP_EFTU_D2 PF03144.25 KKF95989.1 - 0.0015 18.9 0.1 0.0043 17.4 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KKF95989.1 - 0.0022 17.8 0.0 0.0074 16.1 0.0 1.8 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KKF95989.1 - 0.015 15.4 0.0 0.043 13.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase MIT PF04212.18 KKF95990.1 - 5.9e-12 45.5 0.3 1.6e-11 44.1 0.3 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RNA_pol_Rpb1_1 PF04997.12 KKF95991.1 - 4.4e-82 275.9 1.3 6.5e-82 275.3 1.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KKF95991.1 - 2.2e-78 263.4 0.0 3.6e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KKF95991.1 - 4.9e-73 244.8 0.0 1.2e-72 243.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KKF95991.1 - 3.1e-35 121.4 0.0 7.1e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KKF95991.1 - 2.3e-29 101.5 0.5 1.3e-28 99.1 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Latarcin PF10279.9 KKF95991.1 - 0.15 12.5 1.1 0.99 9.9 0.6 2.7 2 1 0 2 2 2 0 Latarcin precursor DDHD PF02862.17 KKF95992.1 - 1.6e-60 205.0 0.0 1.6e-60 205.0 0.0 2.5 2 2 0 2 2 2 1 DDHD domain AAR2 PF05282.11 KKF95992.1 - 0.09 12.2 0.1 0.09 12.2 0.1 1.7 2 0 0 2 2 2 0 AAR2 protein Ank_2 PF12796.7 KKF95993.1 - 0.0012 19.4 0.0 0.0029 18.2 0.0 1.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKF95993.1 - 0.021 15.3 0.1 0.37 11.5 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat CH PF00307.31 KKF95994.1 - 1.1e-72 241.1 0.0 2.1e-19 69.7 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KKF95994.1 - 1.9e-07 31.4 0.9 3.4e-06 27.4 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KKF95994.1 - 6.2e-06 25.4 0.8 0.35 10.5 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KKF95994.1 - 0.0025 17.6 0.5 0.15 12.0 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain CAMSAP_CH PF11971.8 KKF95994.1 - 0.0032 17.3 0.0 1.4 8.8 0.0 3.6 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_5 PF13202.6 KKF95994.1 - 0.42 10.2 2.2 2.8 7.6 0.3 2.9 2 0 0 2 2 2 0 EF hand MBOAT PF03062.19 KKF95995.1 - 5.3e-38 131.3 19.8 5.3e-38 131.3 19.8 2.2 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KKF95995.1 - 1.1e-06 28.9 4.0 3.5e-06 27.2 4.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RRM_1 PF00076.22 KKF95996.1 - 8.7e-12 44.7 0.0 1.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKF95996.1 - 2.1e-05 24.4 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 KKF95997.1 - 2.4e-73 242.1 2.4 8.7e-24 83.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KKF95997.1 - 0.00042 19.6 1.4 0.16 11.1 0.0 3.4 2 1 0 4 4 4 2 Gammaproteobacterial serine protease PT-VENN PF04829.13 KKF95997.1 - 0.31 11.1 3.1 24 5.1 0.0 3.2 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif WD40 PF00400.32 KKF95998.1 - 1.8e-46 155.2 19.9 3.2e-09 37.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF95998.1 - 1.2e-09 38.4 0.9 0.047 14.0 0.0 4.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKF95998.1 - 1.4e-05 24.0 7.7 0.1 11.2 0.1 4.7 1 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKF95998.1 - 0.0007 18.7 0.1 5.4 5.9 0.0 3.7 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KKF95998.1 - 0.011 14.3 0.0 3.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KKF95998.1 - 0.017 15.1 0.7 20 5.3 0.0 4.6 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KKF95998.1 - 0.028 13.8 0.0 0.53 9.6 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain VID27 PF08553.10 KKF95998.1 - 0.082 11.9 0.0 0.4 9.7 0.0 1.9 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain OST3_OST6 PF04756.13 KKF95999.1 - 1.3e-93 313.6 0.0 2e-93 312.9 0.0 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family FtsJ PF01728.19 KKF96000.1 - 1.3e-50 171.9 0.0 2.7e-50 170.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase CENP-F_leu_zip PF10473.9 KKF96000.1 - 0.0039 17.2 8.5 0.0039 17.2 8.5 4.5 2 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KKF96000.1 - 0.015 15.6 20.5 0.015 15.6 20.5 4.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 KKF96000.1 - 0.27 11.3 5.8 2 8.4 0.1 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 KKF96000.1 - 0.33 11.6 0.0 0.33 11.6 0.0 5.8 3 1 4 7 7 7 0 SlyX Ribosomal_L18 PF17135.4 KKF96001.1 - 4.8e-90 300.0 5.0 5.3e-90 299.8 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KKF96001.1 - 0.0073 17.0 0.1 0.0073 17.0 0.1 1.9 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A FlgO PF17680.1 KKF96001.1 - 0.1 12.3 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 FlgO protein PWI PF01480.17 KKF96002.1 - 1.8e-15 57.0 2.6 4.1e-15 55.9 0.7 2.6 3 0 0 3 3 3 1 PWI domain HHH_3 PF12836.7 KKF96002.1 - 0.076 13.3 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ribosomal_S21 PF01165.20 KKF96003.1 - 1.8e-13 50.0 0.4 2.6e-13 49.5 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 SMC_Nse1 PF07574.13 KKF96004.1 - 5.3e-43 147.2 0.0 7.9e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KKF96004.1 - 5.3e-13 49.0 8.3 9.2e-13 48.3 8.3 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 KKF96004.1 - 0.00043 20.6 7.6 0.0008 19.7 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H_2 PF13832.6 KKF96004.1 - 0.018 15.2 5.1 0.039 14.1 5.1 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KKF96004.1 - 0.022 15.0 3.0 0.022 15.0 3.0 2.0 1 1 1 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.22 KKF96004.1 - 0.025 14.5 2.8 0.025 14.5 2.8 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C4pol PF14260.6 KKF96004.1 - 0.12 12.8 0.5 0.12 12.8 0.5 2.1 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-C3HC4_2 PF13923.6 KKF96004.1 - 0.55 10.1 7.1 0.96 9.3 7.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKF96004.1 - 4.7 7.2 7.2 8.8 6.3 7.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKF96004.1 - 5.6 6.9 7.6 50 3.9 7.7 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NACHT_N PF17100.5 KKF96006.1 - 6.1e-70 235.5 2.3 1.1e-69 234.7 2.3 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KKF96006.1 - 5e-15 55.8 0.0 1.3e-14 54.5 0.0 1.7 2 0 0 2 2 2 1 NACHT domain WD40 PF00400.32 KKF96006.1 - 1.3e-09 38.5 10.4 0.022 15.6 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat AAA_19 PF13245.6 KKF96006.1 - 0.0061 16.9 0.0 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KKF96006.1 - 0.025 14.6 0.0 0.073 13.1 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KKF96006.1 - 0.048 13.7 1.2 0.29 11.1 0.0 2.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KKF96006.1 - 0.062 13.6 0.1 0.61 10.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KKF96006.1 - 0.069 12.9 2.6 0.65 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KKF96006.1 - 0.2 12.1 1.0 1.8 9.0 0.0 2.8 3 0 0 3 3 3 0 RNA helicase YqeY PF09424.10 KKF96007.1 - 4.1e-22 78.8 8.3 6.4e-22 78.2 8.3 1.2 1 0 0 1 1 1 1 Yqey-like protein Methyltransf_25 PF13649.6 KKF96007.1 - 2.3e-10 41.0 0.0 1.1e-09 38.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF96007.1 - 2.5e-09 37.6 0.0 1e-08 35.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF96007.1 - 0.00031 20.6 0.0 0.00054 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF96007.1 - 0.0041 17.8 0.0 0.022 15.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KKF96007.1 - 0.0056 16.2 0.0 0.018 14.5 0.0 1.8 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_8 PF05148.15 KKF96007.1 - 0.036 13.9 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase SLAC1 PF03595.17 KKF96008.1 - 2.5e-54 184.7 35.9 2.8e-54 184.6 35.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel CDO_I PF05995.12 KKF96009.1 - 3.2e-08 33.1 0.0 3.6e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I Helicase_C PF00271.31 KKF96010.1 - 3.6e-14 53.0 0.2 1.2e-13 51.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 KKF96010.1 - 2.6e-08 34.1 8.6 6.1e-08 32.9 8.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKF96010.1 - 1e-07 31.7 8.4 2.3e-07 30.5 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKF96010.1 - 2.3e-07 30.6 8.2 5.7e-07 29.3 8.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKF96010.1 - 4.2e-07 29.9 7.4 8.2e-07 28.9 7.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKF96010.1 - 8.1e-07 28.9 5.2 1.5e-06 28.0 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKF96010.1 - 9.4e-06 25.4 7.2 1e-05 25.3 5.9 1.8 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.23 KKF96010.1 - 2.7e-05 23.1 0.1 4.6e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Prok-RING_4 PF14447.6 KKF96010.1 - 0.00016 21.5 10.5 0.0014 18.4 10.6 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 KKF96010.1 - 0.00027 21.0 1.4 0.00053 20.1 1.4 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_11 PF17123.5 KKF96010.1 - 0.0016 18.1 3.3 0.0016 18.1 3.3 2.2 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KKF96010.1 - 0.0052 16.9 9.6 0.011 15.9 9.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KKF96010.1 - 0.0061 16.3 5.8 0.011 15.5 5.4 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Fer4_12 PF13353.6 KKF96010.1 - 0.0074 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain zf-C3HC4_5 PF17121.5 KKF96010.1 - 0.012 15.5 6.2 0.024 14.5 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KKF96010.1 - 0.049 13.8 2.0 0.096 12.8 2.0 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KKF96010.1 - 0.24 11.3 6.8 0.032 14.1 2.6 1.7 2 0 0 2 2 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KKF96010.1 - 0.64 10.4 10.4 0.71 10.2 1.6 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-P11 PF03854.14 KKF96010.1 - 1.9 8.2 5.4 0.37 10.5 0.6 2.1 1 1 1 2 2 2 0 P-11 zinc finger Pterin_4a PF01329.19 KKF96011.1 - 1.4e-23 82.9 0.0 3.1e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase TPR_14 PF13428.6 KKF96011.1 - 0.0068 17.1 1.2 1.8 9.6 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF627 PF04781.12 KKF96011.1 - 0.025 14.6 0.1 0.64 10.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF627) DUF684 PF05075.14 KKF96011.1 - 0.081 11.9 0.0 7.2 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF684) FA_hydroxylase PF04116.13 KKF96012.1 - 3e-24 85.9 17.3 3e-24 85.9 17.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NCA2 PF08637.10 KKF96013.1 - 4.5e-96 321.4 0.0 6.3e-96 321.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ras PF00071.22 KKF96014.1 - 5.3e-64 214.7 0.0 6.3e-64 214.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF96014.1 - 7.2e-34 116.6 0.1 1.4e-33 115.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF96014.1 - 7.7e-13 48.3 0.0 8.4e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKF96014.1 - 3.6e-05 23.4 0.0 0.00011 21.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKF96014.1 - 0.00053 19.4 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKF96014.1 - 0.0068 16.5 0.0 0.016 15.3 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKF96014.1 - 0.013 15.4 0.1 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KKF96014.1 - 0.018 15.3 0.1 0.47 10.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KKF96014.1 - 0.071 13.5 0.0 2.7 8.4 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KKF96014.1 - 0.097 12.2 0.0 0.48 9.9 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PI-PLC-X PF00388.19 KKF96015.1 - 9e-08 31.8 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-X PF00388.19 KKF96016.1 - 2.1e-05 24.2 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-X PF00388.19 KKF96017.1 - 9.5e-10 38.2 0.0 1.6e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain AMP-binding PF00501.28 KKF96019.1 - 6e-65 219.5 0.0 9.2e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KKF96019.1 - 4.1e-64 216.2 0.0 6.1e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Ribosomal_S14 PF00253.21 KKF96019.1 - 2.4e-19 68.8 0.2 5.9e-19 67.6 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PP-binding PF00550.25 KKF96019.1 - 2.5e-11 43.7 0.0 5.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KKF96019.1 - 8.8e-09 35.2 0.0 1.6e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKF96019.1 - 0.00018 21.0 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKF96019.1 - 0.0049 15.9 0.0 0.0079 15.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KKF96019.1 - 0.013 14.6 0.0 0.35 9.9 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 KKF96019.1 - 0.021 14.7 0.0 0.095 12.6 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding AMP-binding_C PF13193.6 KKF96019.1 - 0.029 15.4 0.0 0.1 13.6 0.0 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain adh_short PF00106.25 KKF96019.1 - 0.035 13.6 0.0 0.086 12.3 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 KKF96019.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family PCI PF01399.27 KKF96020.1 - 6.5e-22 78.0 0.1 2.3e-21 76.3 0.1 2.0 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 KKF96020.1 - 5.7e-17 61.5 1.9 1.6e-16 60.1 1.9 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Ribosomal_L18A PF01775.17 KKF96020.1 - 0.013 15.6 7.2 0.074 13.1 2.0 2.7 3 0 0 3 3 3 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF3913 PF13052.6 KKF96020.1 - 1.5 9.2 6.8 1 9.7 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3913) FSH1 PF03959.13 KKF96021.1 - 1e-53 182.2 0.0 1.4e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.11 KKF96021.1 - 0.0018 17.9 0.0 0.0046 16.5 0.0 1.7 2 0 0 2 2 2 1 PE-PPE domain Abhydrolase_6 PF12697.7 KKF96021.1 - 0.016 15.8 0.0 0.033 14.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKF96021.1 - 0.061 13.1 0.0 0.42 10.4 0.0 2.2 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KKF96021.1 - 0.12 11.6 0.1 2.1 7.6 0.0 2.4 2 1 0 3 3 3 0 Serine aminopeptidase, S33 Med3 PF11593.8 KKF96021.1 - 0.41 9.8 11.4 0.55 9.4 11.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NIPSNAP PF07978.13 KKF96022.1 - 1.3e-17 63.9 0.3 3.3e-08 33.7 0.1 2.3 1 1 1 2 2 2 2 NIPSNAP DUF5343 PF17278.2 KKF96022.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5343) CAP PF00188.26 KKF96023.1 - 9.4e-19 68.5 3.1 1.5e-18 67.8 3.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Trypan_PARP PF05887.11 KKF96023.1 - 0.15 12.1 16.5 0.075 13.0 14.0 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF3300 PF11737.8 KKF96023.1 - 0.15 11.6 3.1 0.2 11.2 1.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3300) Rbx_binding PF18113.1 KKF96023.1 - 0.21 11.4 0.2 0.21 11.4 0.2 2.2 2 1 0 2 2 2 0 Rubredoxin binding C-terminal domain SARG PF15385.6 KKF96023.1 - 2.5 7.2 9.7 3.3 6.8 9.7 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Adeno_E1A PF02703.14 KKF96023.1 - 8.2 5.9 11.4 2.8 7.5 8.7 1.5 1 1 1 2 2 2 0 Early E1A protein CoA_transf_3 PF02515.17 KKF96024.1 - 1.8e-45 155.7 0.0 7.5e-44 150.3 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III CHCH PF06747.13 KKF96025.1 - 1.9e-07 31.0 4.6 2.5e-07 30.6 4.6 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KKF96025.1 - 0.026 14.5 1.9 0.037 14.0 1.9 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KKF96025.1 - 0.028 14.5 1.3 0.039 14.0 1.3 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Nup54 PF13874.6 KKF96026.1 - 2.6e-39 134.5 0.2 2.6e-39 134.5 0.2 2.5 3 0 0 3 3 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KKF96026.1 - 2.6e-13 49.3 10.2 4.4e-13 48.6 10.2 1.4 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Sec3_C PF09763.9 KKF96026.1 - 0.001 17.6 1.0 0.006 15.0 0.9 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec3 NPV_P10 PF05531.12 KKF96026.1 - 0.0026 18.2 3.6 2.4 8.7 0.0 3.1 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein BAR_2 PF10455.9 KKF96026.1 - 0.0066 15.6 1.5 0.0096 15.1 1.5 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF1664 PF07889.12 KKF96026.1 - 0.026 14.6 1.1 0.74 9.9 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KKF96026.1 - 0.064 13.5 0.9 9.8 6.5 0.1 3.2 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 KKF96026.1 - 0.07 13.5 1.6 19 5.7 1.3 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 KKF96026.1 - 0.085 13.4 1.5 0.96 10.0 1.0 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4404 PF14357.6 KKF96026.1 - 0.12 13.0 6.9 4.4 8.0 1.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) V-SNARE_C PF12352.8 KKF96026.1 - 0.13 12.6 1.7 0.35 11.2 0.3 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Adhesin_P1_N PF18652.1 KKF96026.1 - 0.19 11.8 2.8 0.4 10.7 1.8 2.1 2 0 0 2 2 1 0 Adhesin P1 N-terminal domain DUF4446 PF14584.6 KKF96026.1 - 0.38 10.7 2.1 0.81 9.7 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) Hemerythrin PF01814.23 KKF96026.1 - 0.44 11.2 3.2 1 10.0 3.1 1.6 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF4407 PF14362.6 KKF96026.1 - 0.45 9.8 6.5 0.67 9.2 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) FapA PF03961.13 KKF96026.1 - 0.8 8.2 3.7 0.95 8.0 2.8 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Nucleoporin_FG PF13634.6 KKF96026.1 - 0.81 10.6 13.6 1.2 10.0 13.6 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeat region MPS2 PF17060.5 KKF96026.1 - 0.83 8.8 5.7 1 8.6 5.2 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 CCDC-167 PF15188.6 KKF96026.1 - 0.94 9.9 7.6 1.1 9.6 4.4 2.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 APG6_N PF17675.1 KKF96026.1 - 1.9 9.0 9.2 3.8 8.0 8.4 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF2205 PF10224.9 KKF96026.1 - 5.3 7.1 7.7 17 5.5 0.1 2.8 2 0 0 2 2 2 0 Short coiled-coil protein GDC-P PF02347.16 KKF96027.1 - 5.8e-161 536.1 0.0 1.9e-151 504.7 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KKF96027.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase WD40 PF00400.32 KKF96028.1 - 3.5e-19 68.8 13.2 6.4e-05 23.6 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF96028.1 - 1.6e-09 37.9 0.0 0.042 14.2 0.0 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF96028.1 - 0.029 13.3 0.7 37 3.1 0.0 3.6 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CorA PF01544.18 KKF96029.1 - 5.9e-14 52.1 0.2 1.2e-13 51.0 0.2 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.17 KKF96029.1 - 0.024 14.4 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 Transposase PK PF00224.21 KKF96030.1 - 2.9e-168 559.2 5.6 3.6e-168 558.9 5.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KKF96030.1 - 1.8e-37 128.2 0.0 6.6e-37 126.3 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KKF96030.1 - 0.001 18.3 0.7 0.0028 16.8 0.7 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KKF96030.1 - 0.0069 15.4 0.1 0.42 9.6 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain GTP1_OBG PF01018.22 KKF96030.1 - 0.09 12.4 0.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 GTP1/OBG NUP PF06516.11 KKF96031.1 - 4.1e-121 404.0 0.0 5e-121 403.7 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Pyrid_oxidase_2 PF13883.6 KKF96032.1 - 5.2e-41 140.4 0.0 1.3e-40 139.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Sec34 PF04136.15 KKF96034.1 - 0.059 13.3 0.9 1.9 8.4 0.0 2.9 2 1 0 2 2 2 0 Sec34-like family DUF4600 PF15372.6 KKF96034.1 - 0.57 10.6 7.4 0.18 12.2 2.3 2.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4600) DivIC PF04977.15 KKF96034.1 - 1.1 9.1 3.5 5.3 6.9 0.5 2.9 2 0 0 2 2 2 0 Septum formation initiator Fungal_TACC PF12709.7 KKF96034.1 - 1.2 9.7 7.2 3.9 8.0 1.4 2.9 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins BLOC1_2 PF10046.9 KKF96034.1 - 1.4 9.3 7.1 3.9 7.9 0.9 3.2 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 KKF96034.1 - 1.4 8.7 6.2 0.73 9.6 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DASH_Dad3 PF08656.10 KKF96034.1 - 3.1 7.9 7.4 24 5.1 2.8 3.0 2 2 0 2 2 2 0 DASH complex subunit Dad3 TMF_DNA_bd PF12329.8 KKF96034.1 - 3.2 7.8 7.3 1.1 9.3 2.1 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DEAD PF00270.29 KKF96035.1 - 1.9e-40 138.5 0.0 3.7e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF96035.1 - 9.2e-26 90.4 0.4 9.3e-25 87.1 0.2 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF96035.1 - 7.3e-08 32.6 0.0 1.7e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 KKF96035.1 - 0.051 14.1 0.4 0.12 13.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Cyclin PF08613.11 KKF96036.1 - 6.1e-06 26.7 0.0 1.4e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KKF96036.1 - 0.0031 17.3 0.1 0.0097 15.7 0.1 1.9 1 1 0 1 1 1 1 Cyclin, N-terminal domain Med8 PF10232.9 KKF96037.1 - 0.015 14.9 5.7 0.017 14.7 5.7 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 FlaE PF07559.14 KKF96037.1 - 0.018 15.6 0.2 0.023 15.3 0.2 1.2 1 0 0 1 1 1 0 Flagellar basal body protein FlaE DUF4604 PF15377.6 KKF96037.1 - 0.023 15.1 3.3 0.03 14.8 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Spt5_N PF11942.8 KKF96037.1 - 3.1 8.9 11.5 4.8 8.2 11.5 1.4 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Pkinase PF00069.25 KKF96038.1 - 4e-60 203.4 0.0 3.7e-59 200.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96038.1 - 2.6e-29 102.3 0.1 4.8e-20 71.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KKF96038.1 - 4.4e-05 24.1 0.3 0.00015 22.4 0.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KKF96038.1 - 0.00091 18.6 0.3 0.0055 16.1 0.0 2.3 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KKF96038.1 - 0.0038 17.2 1.6 0.11 12.3 0.1 3.2 2 1 2 4 4 4 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKF96038.1 - 0.0083 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKF96038.1 - 0.011 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NGP1NT PF08153.12 KKF96039.1 - 1.7e-45 154.3 0.1 2.9e-45 153.6 0.1 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain p450 PF00067.22 KKF96040.1 - 2.2e-73 247.6 0.0 3.3e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KKF96040.1 - 1.9e-28 99.6 0.0 3.1e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KKF96040.1 - 3.5e-24 85.6 0.1 6.9e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KKF96040.1 - 1.2e-10 42.0 0.0 4.9e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KKF96040.1 - 0.01 16.1 0.1 0.028 14.7 0.1 1.7 1 0 0 1 1 1 0 Flavodoxin domain La PF05383.17 KKF96041.1 - 4.2e-19 68.3 0.0 6.6e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KKF96041.1 - 0.0001 22.0 0.1 0.00022 20.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.25 KKF96042.1 - 9.5e-13 47.6 0.0 2.5e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 S4 domain DUF4736 PF15883.5 KKF96042.1 - 0.22 11.2 0.5 1.1 8.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) BID PF06393.11 KKF96042.1 - 0.44 10.1 2.1 0.96 9.0 2.1 1.5 1 0 0 1 1 1 0 BH3 interacting domain (BID) Septin PF00735.18 KKF96043.1 - 1e-118 395.7 0.1 1e-118 395.7 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KKF96043.1 - 1.7e-08 34.5 1.2 3.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKF96043.1 - 1.5e-06 27.9 1.5 0.00012 21.6 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KKF96043.1 - 5.2e-05 23.8 0.8 0.013 16.0 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 KKF96043.1 - 0.00037 20.7 0.0 0.00084 19.5 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KKF96043.1 - 0.00055 19.3 1.5 0.001 18.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KKF96043.1 - 0.00084 19.3 0.6 0.00084 19.3 0.6 3.2 3 1 0 3 3 2 1 RsgA GTPase AAA_16 PF13191.6 KKF96043.1 - 0.0018 18.7 0.1 0.0047 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 KKF96043.1 - 0.0058 16.3 0.1 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.6 KKF96043.1 - 0.0061 16.8 1.2 0.017 15.4 0.0 2.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKF96043.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KKF96043.1 - 0.016 15.0 3.2 0.37 10.5 0.0 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KKF96043.1 - 0.019 15.5 5.6 3.4 8.1 5.3 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KKF96043.1 - 0.024 14.4 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KKF96043.1 - 0.043 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 KKF96043.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KKF96043.1 - 0.071 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KKF96043.1 - 0.072 13.5 0.6 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Exonuc_VII_L PF02601.15 KKF96043.1 - 0.33 10.5 7.1 0.53 9.8 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 KKF96043.1 - 0.67 10.0 3.8 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 KKF96043.1 - 0.82 9.7 10.6 0.92 9.5 0.1 3.3 2 2 0 3 3 2 0 Dynamin family DUF3987 PF13148.6 KKF96043.1 - 1.6 7.6 0.0 1.6 7.6 0.0 2.4 2 1 1 3 3 2 0 Protein of unknown function (DUF3987) Atg14 PF10186.9 KKF96043.1 - 3.2 6.7 9.8 4.9 6.2 9.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PLA2_B PF01735.18 KKF96044.1 - 2.8e-32 111.8 0.0 5e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Spc29 PF17082.5 KKF96044.1 - 0.16 11.8 0.2 0.28 11.0 0.2 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 DHO_dh PF01180.21 KKF96045.1 - 8.7e-68 228.7 0.0 1.1e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KKF96045.1 - 4.1e-05 22.8 0.3 0.0013 17.8 0.1 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase PcrB PF01884.17 KKF96045.1 - 0.0043 16.5 0.3 2.7 7.4 0.0 2.3 2 0 0 2 2 2 2 PcrB family TetR_C_16 PF17920.1 KKF96045.1 - 0.071 13.4 1.5 0.26 11.5 0.5 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain dsrm PF00035.26 KKF96047.1 - 4.9e-08 33.6 0.0 9.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KKF96047.1 - 7.8e-08 32.5 0.0 0.0042 17.3 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KKF96047.1 - 0.00072 20.1 0.0 0.0033 18.0 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease III domain Palm_thioest PF02089.15 KKF96048.1 - 6.3e-78 261.9 0.0 7.6e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KKF96048.1 - 0.003 17.0 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) RMI2 PF16100.5 KKF96049.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 GRP PF07172.11 KKF96049.1 - 0.028 15.1 13.5 0.055 14.2 13.5 1.4 1 0 0 1 1 1 0 Glycine rich protein family MARVEL PF01284.23 KKF96051.1 - 0.0037 17.3 4.8 0.0037 17.3 4.8 2.2 1 1 0 2 2 2 2 Membrane-associating domain DUF1127 PF06568.11 KKF96052.1 - 3.9 7.3 7.9 1.8 8.3 5.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Ribosomal_L1 PF00687.21 KKF96053.1 - 2.2e-65 220.2 0.7 2.2e-65 220.2 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family LRAT PF04970.13 KKF96053.1 - 0.15 12.4 0.2 0.97 9.7 0.0 2.3 3 0 0 3 3 3 0 Lecithin retinol acyltransferase HSP70 PF00012.20 KKF96054.1 - 2.2e-167 557.9 0.6 2.2e-167 557.9 0.6 1.3 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KKF96054.1 - 2.4e-12 46.3 0.1 5.4e-12 45.2 0.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein GTP_EFTU PF00009.27 KKF96055.1 - 1.4e-34 119.4 0.0 4.8e-34 117.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KKF96055.1 - 5.8e-20 71.4 0.0 1.6e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 KKF96055.1 - 5.2e-09 35.9 0.3 2.1e-08 33.9 0.3 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KKF96055.1 - 1.4e-07 31.6 0.2 7.6e-06 26.0 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KKF96055.1 - 2e-07 31.3 0.3 2e-07 31.3 0.3 3.6 4 0 0 4 4 4 1 Elongation factor Tu domain 2 Roc PF08477.13 KKF96055.1 - 2.1e-05 24.7 0.0 7.3e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KKF96055.1 - 0.0013 18.6 0.1 0.0069 16.2 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.22 KKF96055.1 - 0.02 14.5 0.0 0.092 12.3 0.0 2.3 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.6 KKF96055.1 - 0.13 12.5 0.6 2.5 8.4 0.4 3.0 2 1 0 2 2 2 0 AAA domain RabGAP-TBC PF00566.18 KKF96056.1 - 3.1e-19 69.5 0.0 3.9e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Dpy-30 PF05186.13 KKF96056.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Dpy-30 motif eIF-5a PF01287.20 KKF96057.1 - 8.9e-23 80.2 2.3 1.3e-22 79.7 2.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KKF96057.1 - 0.0025 17.8 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain NTR2 PF15458.6 KKF96057.1 - 0.0026 17.4 0.2 0.0029 17.2 0.2 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 Ribosomal_L40e PF01020.17 KKF96058.1 - 1.9e-31 107.7 10.1 2.8e-31 107.1 10.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.23 KKF96058.1 - 2.1e-31 107.4 0.3 2.9e-31 107.0 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KKF96058.1 - 1.9e-13 50.0 0.3 2.7e-13 49.5 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KKF96058.1 - 2.3e-05 24.8 0.1 8.9e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KKF96058.1 - 0.0031 17.8 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KKF96058.1 - 0.0043 16.9 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KKF96058.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KKF96058.1 - 0.03 14.9 0.0 0.034 14.7 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Yip1 PF04893.17 KKF96059.1 - 5.6e-11 42.5 14.1 1.2e-10 41.3 14.1 1.6 1 1 0 1 1 1 1 Yip1 domain Rhodanese PF00581.20 KKF96060.1 - 3e-10 40.6 0.0 3.3e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain Mit_ribos_Mrp51 PF11709.8 KKF96061.1 - 5.1e-113 378.4 0.0 6.1e-113 378.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.18 KKF96062.1 - 1.1e-59 199.7 0.5 1.3e-59 199.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal S17 RPAP2_Rtr1 PF04181.13 KKF96063.1 - 1.4e-23 83.0 0.0 3.4e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF1883 PF08980.10 KKF96063.1 - 0.07 13.1 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) NUC PF18510.1 KKF96063.1 - 0.1 13.1 1.4 0.89 10.0 0.6 2.3 2 0 0 2 2 2 0 Nuclease domain SH3_1 PF00018.28 KKF96064.1 - 2.1e-10 40.1 0.2 3.3e-10 39.4 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKF96064.1 - 1.8e-09 37.1 0.0 2.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KKF96064.1 - 1.9e-08 34.0 0.1 3.3e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain CHAP PF05257.16 KKF96065.1 - 0.039 14.5 0.4 0.13 12.8 0.4 1.8 1 1 0 1 1 1 0 CHAP domain DNase-RNase PF02577.14 KKF96065.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Bifunctional nuclease GCP_C_terminal PF04130.13 KKF96067.1 - 1.3e-18 67.5 0.0 1.9e-17 63.7 0.0 2.3 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Methyltransf_33 PF10017.9 KKF96068.1 - 9.7e-65 218.7 0.0 1.7e-64 217.9 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KKF96068.1 - 1e-19 71.1 0.2 5.6e-19 68.7 0.2 1.9 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KKF96068.1 - 1.5e-07 32.0 0.1 2.9e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 DinB superfamily IF-2B PF01008.17 KKF96069.1 - 1.1e-38 133.1 0.0 1.4e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family AA_kinase PF00696.28 KKF96069.1 - 0.16 11.6 0.3 0.63 9.6 0.3 1.9 1 1 0 1 1 1 0 Amino acid kinase family DUF1681 PF07933.14 KKF96070.1 - 4.2e-56 188.8 0.0 6.2e-56 188.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) ETF PF01012.21 KKF96071.1 - 7.5e-42 143.3 0.4 1.2e-41 142.6 0.3 1.4 1 1 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KKF96071.1 - 1.3e-33 114.9 0.5 2.7e-33 113.8 0.5 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.17 KKF96072.1 - 3.9e-31 107.2 0.1 8e-31 106.2 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KKF96072.1 - 1.4e-27 95.5 6.1 2.9e-27 94.4 6.1 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KKF96072.1 - 3.2e-06 27.2 0.2 7.7e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKF96072.1 - 0.018 15.3 0.1 0.038 14.2 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Carn_acyltransf PF00755.20 KKF96073.1 - 1.1e-200 668.3 0.0 1.2e-200 668.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SUD-M PF11633.8 KKF96073.1 - 0.15 11.8 0.1 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Single-stranded poly(A) binding domain CAP_N PF01213.19 KKF96074.1 - 8.4e-117 390.2 0.1 1.3e-116 389.6 0.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KKF96074.1 - 1.9e-52 177.1 3.9 2.8e-52 176.5 3.9 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Ribosomal_60s PF00428.19 KKF96074.1 - 0.6 10.7 8.3 4.8 7.9 2.0 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Ammonium_transp PF00909.21 KKF96075.1 - 1.9e-48 165.1 6.0 2.1e-48 165.0 6.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Trep_Strep PF09605.10 KKF96075.1 - 0.32 11.0 7.5 0.06 13.3 3.9 1.6 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Filament PF00038.21 KKF96077.1 - 0.00045 19.9 9.9 0.00045 19.9 9.9 5.2 3 2 0 4 4 4 2 Intermediate filament protein RNB PF00773.19 KKF96078.1 - 6.8e-52 176.8 0.0 1e-51 176.2 0.0 1.3 1 0 0 1 1 1 1 RNB domain DUF1752 PF08550.10 KKF96079.1 - 9.7e-10 38.1 4.1 9.7e-10 38.1 4.1 1.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) NOA36 PF06524.12 KKF96079.1 - 4.1 6.6 5.9 6.8 5.9 5.9 1.2 1 0 0 1 1 1 0 NOA36 protein Met_10 PF02475.16 KKF96080.1 - 1.9e-70 236.6 0.1 2.9e-70 236.1 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Sec10 PF07393.11 KKF96081.1 - 1.5e-208 694.7 0.2 1.9e-208 694.4 0.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF421 PF04239.12 KKF96081.1 - 0.059 13.1 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF421) DUF4050 PF13259.6 KKF96082.1 - 0.11 12.8 1.8 0.19 12.0 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Chitin_synth_2 PF03142.15 KKF96083.1 - 4e-281 933.2 0.4 6.5e-281 932.5 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KKF96083.1 - 2.4e-12 47.2 2.7 2.4e-12 47.2 2.7 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKF96083.1 - 1.1e-10 41.8 0.3 2.6e-09 37.3 0.0 2.8 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KKF96083.1 - 0.00039 19.9 0.1 0.006 16.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KKF96083.1 - 0.014 15.3 0.0 0.14 12.0 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase family 2 Cyt-b5 PF00173.28 KKF96083.1 - 0.1 12.8 0.0 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 Cytochrome b5-like Heme/Steroid binding domain SEN1_N PF12726.7 KKF96084.1 - 4.5e-160 534.4 0.5 6.2e-160 533.9 0.5 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KKF96084.1 - 2.1e-68 231.0 1.5 2.1e-68 231.0 1.5 2.9 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KKF96084.1 - 1.7e-59 200.8 0.0 3.1e-59 200.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF96084.1 - 4.6e-07 30.3 2.8 8.6e-07 29.4 0.4 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKF96084.1 - 1.5e-06 28.1 5.5 0.00082 19.1 0.4 3.4 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KKF96084.1 - 1.6e-05 24.8 0.2 0.012 15.3 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KKF96084.1 - 0.045 14.0 0.4 1.4 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KKF96084.1 - 0.05 14.0 0.8 2.4 8.6 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Red1 PF07964.11 KKF96084.1 - 4.2 5.5 9.0 8.5 4.5 9.0 1.4 1 0 0 1 1 1 0 Rec10 / Red1 PCB_OB PF17092.5 KKF96084.1 - 4.7 8.0 7.0 26 5.6 0.0 3.3 3 0 0 3 3 3 0 Penicillin-binding protein OB-like domain Ric8 PF10165.9 KKF96086.1 - 1.6e-57 195.5 3.6 2.2e-35 122.6 0.3 2.2 1 1 1 2 2 2 2 Guanine nucleotide exchange factor synembryn fn3_2 PF16893.5 KKF96086.1 - 8.7e-40 134.8 0.1 1.8e-39 133.7 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KKF96086.1 - 2.3e-23 81.9 1.0 4.5e-23 80.9 1.0 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KKF96086.1 - 5.8e-11 42.2 0.0 1.3e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KKF96086.1 - 5.2e-10 39.6 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKF96086.1 - 6.1e-05 23.3 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 KKF96086.1 - 0.0054 16.9 0.0 0.019 15.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KKF96086.1 - 0.036 14.4 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain Lyase_1 PF00206.20 KKF96087.1 - 1.2e-25 90.6 0.0 1.9e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KKF96087.1 - 1.4e-17 64.0 0.1 6.3e-17 61.9 0.0 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Peptidase_C65 PF10275.9 KKF96088.1 - 1e-58 198.7 0.0 1.3e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Mating_N PF12731.7 KKF96088.1 - 0.066 13.3 0.8 0.16 12.1 0.3 1.9 2 0 0 2 2 2 0 Mating-type protein beta 1 ICL PF00463.21 KKF96090.1 - 1.9e-175 584.4 0.1 3.1e-175 583.7 0.1 1.3 1 0 0 1 1 1 1 Isocitrate lyase family PCI PF01399.27 KKF96090.1 - 1.5e-14 54.4 0.0 5.2e-14 52.6 0.0 2.0 1 0 0 1 1 1 1 PCI domain PEP_mutase PF13714.6 KKF96090.1 - 2.6e-10 40.2 0.7 4.6e-09 36.1 0.0 2.4 3 0 0 3 3 3 1 Phosphoenolpyruvate phosphomutase RPM2 PF08579.11 KKF96090.1 - 0.0031 17.9 0.5 0.63 10.4 0.1 2.5 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_12 PF13424.6 KKF96090.1 - 0.11 12.8 0.1 1.5 9.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF755 PF05501.11 KKF96090.1 - 0.13 12.6 0.0 0.45 10.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CWC25 PF12542.8 KKF96091.1 - 1.4e-24 86.9 0.4 1.4e-24 86.9 0.4 2.5 2 1 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KKF96091.1 - 8.1e-15 54.7 3.8 8.1e-15 54.7 3.8 2.4 1 1 1 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR Pectate_lyase_3 PF12708.7 KKF96092.1 - 2.6e-86 288.9 11.2 4.4e-75 252.2 0.8 3.2 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KKF96092.1 - 7.3e-08 32.0 2.0 0.0073 16.0 0.2 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Methyltrn_RNA_3 PF02598.17 KKF96093.1 - 2.9e-98 328.9 0.0 3.3e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Thioredoxin PF00085.20 KKF96094.1 - 1.4e-27 95.7 0.1 3.1e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Rsm22 PF09243.10 KKF96094.1 - 1.6e-25 89.9 0.0 5e-25 88.3 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Thioredoxin_8 PF13905.6 KKF96094.1 - 7.6e-05 23.0 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KKF96094.1 - 0.0025 18.3 0.0 0.0071 16.8 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KKF96094.1 - 0.0042 16.5 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Methyltransf_12 PF08242.12 KKF96094.1 - 0.0044 17.7 0.0 0.013 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AhpC-TSA PF00578.21 KKF96094.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KKF96094.1 - 0.041 14.1 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KKF96094.1 - 0.18 11.5 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Redoxin Mannosyl_trans3 PF11051.8 KKF96095.1 - 0.01 15.2 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KKF96095.1 - 0.012 15.1 0.3 0.012 15.1 0.3 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 8 Ribosomal_L35Ae PF01247.18 KKF96096.1 - 5.1e-40 135.5 0.3 5.8e-40 135.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KKF96096.1 - 0.0019 18.4 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain G6PD_C PF02781.16 KKF96097.1 - 4e-115 384.0 0.0 6.2e-115 383.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KKF96097.1 - 4.5e-60 203.3 0.0 8e-60 202.5 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Med14 PF08638.11 KKF96098.1 - 4e-57 192.7 0.1 6e-57 192.2 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 Amino_oxidase PF01593.24 KKF96099.1 - 3e-20 72.9 0.2 5e-20 72.2 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKF96099.1 - 9e-12 45.0 0.0 2.2e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKF96099.1 - 4.8e-08 33.0 0.2 1.9e-07 31.0 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKF96099.1 - 6e-07 28.9 0.0 6.6e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family MCRA PF06100.11 KKF96099.1 - 0.003 16.4 0.0 0.0061 15.4 0.0 1.4 1 0 0 1 1 1 1 MCRA family Pyr_redox_2 PF07992.14 KKF96099.1 - 0.0058 15.9 0.0 0.031 13.5 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKF96099.1 - 0.0083 16.1 0.2 0.06 13.3 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKF96099.1 - 0.0095 16.5 1.6 0.044 14.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_3_Rpc31 PF11705.8 KKF96099.1 - 1.7 8.9 9.2 3.6 7.8 9.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.6 KKF96099.1 - 2.4 8.6 6.1 5.6 7.4 6.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.19 KKF96099.1 - 2.7 8.7 5.5 6.5 7.4 5.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-CCCH_2 PF14608.6 KKF96100.1 - 2.3e-11 43.7 56.2 0.0055 17.1 16.7 5.6 5 1 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KKF96100.1 - 0.0035 17.6 0.0 0.0061 16.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) DEAD PF00270.29 KKF96101.1 - 4.7e-16 59.0 0.0 1.1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KKF96101.1 - 1e-07 32.2 0.0 2.7e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 KKF96101.1 - 0.012 16.2 0.0 0.037 14.6 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Helicase_C PF00271.31 KKF96101.1 - 0.024 15.0 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Helicase conserved C-terminal domain HTH_45 PF14947.6 KKF96101.1 - 0.1 12.6 0.1 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix zf-HC5HC2H_2 PF13832.6 KKF96102.1 - 3.6e-18 65.7 1.6 3.6e-18 65.7 1.6 4.3 4 0 0 4 4 4 2 PHD-zinc-finger like domain BAH PF01426.18 KKF96102.1 - 4.6e-18 65.2 0.0 1.1e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KKF96102.1 - 5.7e-14 52.1 3.1 5.7e-14 52.1 3.1 4.9 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 KKF96102.1 - 6.2e-11 42.0 56.7 2.4e-06 27.3 7.0 6.2 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 KKF96102.1 - 1.4e-06 27.7 3.6 1.4e-06 27.7 3.6 5.5 6 0 0 6 6 6 2 PHD-finger ELM2 PF01448.24 KKF96102.1 - 0.00059 20.5 0.6 0.0032 18.2 0.1 2.7 2 0 0 2 2 2 1 ELM2 domain GATA PF00320.27 KKF96102.1 - 0.0053 16.3 1.5 0.0053 16.3 1.5 4.2 5 0 0 5 5 5 1 GATA zinc finger DnaJ_C PF01556.18 KKF96103.1 - 4.7e-38 130.6 0.1 6.4e-38 130.1 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKF96103.1 - 4.9e-26 90.6 1.2 8.4e-26 89.9 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKF96103.1 - 2.1e-14 53.6 18.9 4.1e-14 52.7 18.9 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KKF96103.1 - 0.43 10.6 10.4 0.55 10.3 3.7 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MRC1 PF09444.10 KKF96104.1 - 1.6e-36 126.0 18.5 1.6e-36 126.0 18.5 8.5 6 2 2 9 9 9 1 MRC1-like domain ThiF PF00899.21 KKF96105.1 - 2.6e-39 135.1 0.0 3.2e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 KKF96105.1 - 3.1e-05 23.8 0.0 4.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 KKF96105.1 - 0.00011 22.2 0.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KKF96105.1 - 0.00069 19.0 0.0 0.066 12.6 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 KKF96107.1 - 7.7e-58 196.0 0.1 3e-40 138.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family IBR PF01485.21 KKF96108.1 - 4.2e-07 30.1 36.2 3.9e-05 23.8 12.0 3.6 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KKF96108.1 - 0.02 15.2 10.0 0.02 15.2 10.0 3.4 3 0 0 3 3 3 0 Ring finger domain BRO1 PF03097.18 KKF96109.1 - 8.3e-06 24.8 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Alg6_Alg8 PF03155.15 KKF96110.1 - 2.7e-127 425.7 31.8 6.8e-80 269.4 12.8 2.4 3 0 0 3 3 3 2 ALG6, ALG8 glycosyltransferase family SNARE_assoc PF09335.11 KKF96111.1 - 0.034 14.6 0.1 0.07 13.6 0.1 1.4 1 0 0 1 1 1 0 SNARE associated Golgi protein Glycophorin_A PF01102.18 KKF96111.1 - 0.16 12.2 0.0 0.16 12.2 0.0 2.9 3 0 0 3 3 3 0 Glycophorin A VSP PF03302.13 KKF96111.1 - 0.47 9.3 6.9 0.022 13.6 1.2 1.6 2 0 0 2 2 2 0 Giardia variant-specific surface protein G_path_suppress PF15991.5 KKF96111.1 - 3.9 7.5 21.2 0.019 15.1 11.7 1.8 2 1 0 2 2 2 0 G-protein pathway suppressor Nitroreductase PF00881.24 KKF96112.1 - 1.5e-10 41.4 0.0 1.8e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PS_Dcarbxylase PF02666.15 KKF96113.1 - 3.1e-46 157.5 0.0 6.7e-22 78.0 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.22 KKF96113.1 - 0.17 11.7 0.1 0.36 10.7 0.1 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme DUF1682 PF07946.14 KKF96114.1 - 0.52 9.5 4.6 0.66 9.1 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MAJIN PF15077.6 KKF96114.1 - 0.98 9.2 6.0 0.29 10.9 1.9 1.8 2 0 0 2 2 2 0 Membrane-anchored junction protein MscS_TM PF12794.7 KKF96114.1 - 5.1 5.9 8.7 8.9 5.1 8.7 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Peptidase_C12 PF01088.21 KKF96115.1 - 2.4e-68 230.1 0.0 3e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KKF96115.1 - 7.7e-09 35.3 0.2 1.5e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Fibrillarin PF01269.17 KKF96116.1 - 7.7e-90 300.0 0.1 8.9e-90 299.8 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KKF96116.1 - 0.00025 20.8 0.0 0.00034 20.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KKF96116.1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KKF96116.1 - 0.18 11.9 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ribosomal_L22 PF00237.19 KKF96117.1 - 1.4e-41 140.8 0.0 2.5e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ABC_tran PF00005.27 KKF96118.1 - 7.7e-35 120.4 0.1 4e-34 118.1 0.0 2.1 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.19 KKF96118.1 - 6.1e-06 25.8 0.2 0.0004 19.9 0.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKF96118.1 - 0.00048 20.4 0.2 0.0048 17.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKF96118.1 - 0.0016 18.9 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KKF96118.1 - 0.003 17.3 0.0 0.007 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KKF96118.1 - 0.0078 15.9 0.1 0.023 14.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KKF96118.1 - 0.012 15.3 0.5 0.27 10.9 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 KKF96118.1 - 0.022 14.3 0.2 0.18 11.3 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKF96118.1 - 0.024 14.6 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KKF96118.1 - 0.03 14.7 0.2 0.26 11.7 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KKF96118.1 - 0.032 13.0 1.1 0.045 12.5 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DEAD PF00270.29 KKF96118.1 - 0.09 12.5 0.1 0.41 10.4 0.1 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF3987 PF13148.6 KKF96118.1 - 0.098 11.7 0.0 0.098 11.7 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_18 PF13238.6 KKF96118.1 - 0.12 12.9 0.3 0.33 11.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKF96118.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KKF96118.1 - 0.46 11.0 6.1 3.5 8.1 0.5 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KKF96118.1 - 2.3 8.5 8.4 0.94 9.8 1.8 2.9 3 1 0 3 3 1 0 Putative exonuclease SbcCD, C subunit Clathrin_lg_ch PF01086.17 KKF96119.1 - 1.6e-70 237.8 8.8 1.8e-70 237.6 8.8 1.0 1 0 0 1 1 1 1 Clathrin light chain RE_HindIII PF09518.10 KKF96119.1 - 0.024 13.9 0.4 0.031 13.5 0.4 1.1 1 0 0 1 1 1 0 HindIII restriction endonuclease COX7a PF02238.15 KKF96120.1 - 6.6e-18 64.9 0.4 7.4e-18 64.7 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Adaptin_N PF01602.20 KKF96121.1 - 9.3e-145 483.1 5.7 1.1e-144 482.8 5.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region EF-hand_1 PF00036.32 KKF96121.1 - 2.7e-33 111.0 12.9 1.7e-08 33.4 0.1 4.9 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KKF96121.1 - 8.4e-30 103.0 8.8 2.8e-14 53.3 1.7 3.7 5 0 0 5 5 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KKF96121.1 - 5.9e-27 93.3 11.6 3.5e-13 49.2 0.1 5.0 2 1 3 5 5 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KKF96121.1 - 7.7e-25 84.7 7.5 2.4e-08 33.3 0.2 5.0 4 0 0 4 4 4 4 EF-hand domain Alpha_adaptinC2 PF02883.20 KKF96121.1 - 4.5e-20 72.0 0.0 1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain EF-hand_5 PF13202.6 KKF96121.1 - 4.5e-19 67.0 9.6 2.9e-05 23.4 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KKF96121.1 - 7e-14 51.9 0.2 4.8e-08 33.2 0.0 3.6 4 0 0 4 4 2 2 EF-hand domain Cnd1 PF12717.7 KKF96121.1 - 2.4e-08 34.2 7.1 0.00027 21.0 0.0 4.7 2 2 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 SPARC_Ca_bdg PF10591.9 KKF96121.1 - 9.5e-06 25.9 0.2 0.23 11.8 0.1 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3730 PF12530.8 KKF96121.1 - 1.3e-05 24.8 0.1 0.00023 20.8 0.1 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) EF-hand_4 PF12763.7 KKF96121.1 - 7e-05 22.7 1.2 0.16 12.0 0.1 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 KKF96121.1 - 0.00022 21.2 1.2 0.089 12.7 0.4 2.7 1 1 1 2 2 2 1 Tellurite resistance protein TerB UPF0154 PF03672.13 KKF96121.1 - 0.00032 20.7 0.0 0.098 12.7 0.0 2.9 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0154) HEAT_2 PF13646.6 KKF96121.1 - 0.00051 20.4 0.1 3 8.3 0.0 3.8 2 1 0 2 2 2 2 HEAT repeats RIX1 PF08167.12 KKF96121.1 - 0.0076 16.0 0.0 0.044 13.5 0.0 2.3 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis EF-hand_11 PF08976.11 KKF96121.1 - 0.008 17.0 1.0 0.043 14.7 0.1 2.6 2 1 1 3 3 2 1 EF-hand domain RNA_pol_Rpb4 PF03874.16 KKF96121.1 - 0.021 15.1 0.3 4.9 7.5 0.1 3.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 EFhand_Ca_insen PF08726.10 KKF96121.1 - 0.032 14.3 0.1 0.11 12.6 0.1 2.0 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Cohesin_HEAT PF12765.7 KKF96121.1 - 0.077 13.3 0.2 0.66 10.3 0.2 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF3349 PF11829.8 KKF96121.1 - 0.083 13.7 6.4 36 5.2 0.2 4.6 3 1 2 5 5 4 0 Protein of unknown function (DUF3349) Caleosin PF05042.13 KKF96121.1 - 0.094 12.6 0.3 4.4 7.2 0.3 3.1 1 1 0 1 1 1 0 Caleosin related protein Peptidase_M73 PF12389.8 KKF96121.1 - 0.095 12.5 1.2 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Camelysin metallo-endopeptidase HEAT PF02985.22 KKF96121.1 - 0.18 12.1 1.6 7.8 7.1 0.1 4.0 4 0 0 4 4 2 0 HEAT repeat Ndufs5 PF10200.9 KKF96122.1 - 0.00022 21.4 0.1 0.00027 21.1 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.17 KKF96122.1 - 0.0023 18.1 0.3 0.0032 17.7 0.3 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DUF3128 PF11326.8 KKF96122.1 - 0.01 16.2 2.6 0.026 14.9 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) UPF0203 PF05254.12 KKF96122.1 - 0.029 14.6 0.6 0.043 14.1 0.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) CHCH PF06747.13 KKF96122.1 - 0.082 13.1 0.6 0.19 11.9 0.6 1.7 1 1 0 1 1 1 0 CHCH domain RRM_1 PF00076.22 KKF96123.1 - 2.5e-21 75.3 0.0 4.2e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKF96123.1 - 0.0002 21.0 0.0 0.00066 19.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMC_N PF02463.19 KKF96124.1 - 5e-60 202.7 0.0 8.4e-60 201.9 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKF96124.1 - 1.5e-25 89.8 0.0 7.1e-25 87.6 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KKF96124.1 - 1.2e-10 42.2 19.5 1.2e-10 42.2 19.5 6.6 3 2 1 4 4 3 1 AAA domain AAA_21 PF13304.6 KKF96124.1 - 6e-08 32.8 16.8 3.1e-05 23.9 0.0 4.7 5 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKF96124.1 - 8.4e-08 31.8 0.0 1.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 KKF96124.1 - 8.6e-06 26.1 94.9 0.0027 18.0 17.1 5.7 4 1 1 5 5 5 3 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KKF96124.1 - 4.1e-05 22.6 105.3 0.0051 15.7 11.1 6.4 3 2 3 6 6 6 4 Spc7 kinetochore protein DHR10 PF18595.1 KKF96124.1 - 0.0021 18.1 10.7 0.0021 18.1 10.7 9.1 6 3 2 8 8 7 3 Designed helical repeat protein 10 domain HAP1_N PF04849.13 KKF96124.1 - 0.0034 16.6 15.0 0.0034 16.6 15.0 6.5 3 2 1 5 5 3 1 HAP1 N-terminal conserved region Filament PF00038.21 KKF96124.1 - 0.0056 16.3 8.9 0.0056 16.3 8.9 7.1 3 2 2 6 6 6 3 Intermediate filament protein TBCC_N PF16752.5 KKF96124.1 - 0.01 16.3 10.1 0.01 16.3 10.1 7.8 5 2 4 10 10 8 0 Tubulin-specific chaperone C N-terminal domain AAA_15 PF13175.6 KKF96124.1 - 0.017 14.9 57.7 0.008 15.9 32.0 3.9 2 2 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 KKF96124.1 - 0.031 14.5 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Fib_alpha PF08702.10 KKF96124.1 - 0.28 11.4 67.2 0.045 13.9 7.3 6.5 5 1 0 6 6 6 0 Fibrinogen alpha/beta chain family ABC_tran PF00005.27 KKF96124.1 - 0.81 10.2 0.0 0.81 10.2 0.0 7.2 4 3 1 5 5 4 0 ABC transporter EF-hand_2 PF09068.11 KKF96124.1 - 0.9 9.7 5.5 42 4.3 0.5 4.0 3 1 0 3 3 3 0 EF hand TFIIE_alpha PF02002.17 KKF96125.1 - 3.2e-09 36.6 0.0 7.7e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit MAPEG PF01124.18 KKF96126.1 - 1e-17 64.2 2.3 1.2e-17 64.0 2.3 1.1 1 0 0 1 1 1 1 MAPEG family SRP_TPR_like PF17004.5 KKF96127.1 - 1.4e-22 79.9 1.2 2e-22 79.4 0.4 1.6 2 0 0 2 2 2 1 Putative TPR-like repeat HrpB1_HrpK PF09613.10 KKF96127.1 - 0.0016 18.1 0.8 0.046 13.4 0.0 3.0 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_19 PF14559.6 KKF96127.1 - 0.0031 18.0 3.6 0.69 10.5 0.2 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 KKF96127.1 - 0.0036 17.3 1.3 3.5 7.7 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF1955 PF09205.10 KKF96127.1 - 0.0055 16.5 0.7 0.52 10.0 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1955) TPR_14 PF13428.6 KKF96127.1 - 0.013 16.3 5.5 4.2 8.4 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF96127.1 - 0.027 14.7 1.6 0.2 11.9 0.2 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KKF96127.1 - 0.066 13.3 5.0 7.2 7.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KKF96127.1 - 0.11 12.9 1.5 4.3 7.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKF96127.1 - 0.16 12.6 1.7 29 5.4 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.14 KKF96128.1 - 2.5e-24 84.9 0.1 3.7e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KKF96128.1 - 9.3e-16 58.1 0.1 1.5e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain N_formyltrans_C PF18216.1 KKF96128.1 - 0.051 13.3 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Colicin PF01024.19 KKF96128.1 - 0.098 12.5 0.7 0.89 9.4 0.0 2.1 2 0 0 2 2 2 0 Colicin pore forming domain TRAM_LAG1_CLN8 PF03798.16 KKF96129.1 - 2.9e-46 157.7 16.7 4.2e-46 157.2 16.7 1.2 1 0 0 1 1 1 1 TLC domain A_deaminase PF00962.22 KKF96130.1 - 1.4e-120 402.5 0.1 2.7e-120 401.6 0.1 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase SHD1 PF03983.12 KKF96130.1 - 8.7e-33 112.0 0.2 4e-32 109.8 0.1 2.1 2 0 0 2 2 2 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 KKF96130.1 - 1.5e-29 101.4 5.4 1.1e-12 47.4 0.0 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KKF96130.1 - 3.5e-23 81.2 3.3 5.2e-07 29.4 0.0 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 KKF96130.1 - 6.6e-13 48.1 0.0 0.0058 16.3 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SAM_4 PF18017.1 KKF96130.1 - 8.4e-06 25.7 0.0 4.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 KKF96130.1 - 0.0076 16.5 0.3 1.6 9.1 0.1 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain SH3_10 PF17902.1 KKF96130.1 - 0.019 15.0 0.6 2.1 8.5 0.0 3.4 4 0 0 4 4 4 0 SH3 domain WD40 PF00400.32 KKF96131.1 - 1.8e-13 50.7 2.8 0.16 12.9 0.2 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF96131.1 - 0.01 16.1 0.0 3 8.2 0.0 3.6 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Formyl_trans_N PF00551.19 KKF96132.1 - 1.5e-41 142.1 0.0 1.8e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.18 KKF96132.1 - 0.072 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Ion_trans PF00520.31 KKF96133.1 - 4.1e-129 429.0 86.8 2e-42 145.1 3.8 4.5 4 1 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KKF96133.1 - 0.0014 17.4 2.6 0.0014 17.4 2.6 7.9 7 3 3 10 10 10 3 Polycystin cation channel EF-hand_7 PF13499.6 KKF96133.1 - 0.012 16.1 0.0 0.032 14.7 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KKF96133.1 - 0.012 15.1 0.0 0.08 12.5 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 KKF96133.1 - 0.019 14.9 0.0 0.098 12.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain GPHH PF16905.5 KKF96133.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated GlcNAc PF11397.8 KKF96134.1 - 0.12 11.9 7.2 0.2 11.1 7.2 1.3 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) MID_MedPIWI PF18296.1 KKF96134.1 - 2 8.1 12.8 8.4 6.1 0.4 2.3 2 0 0 2 2 2 0 MID domain of medPIWI Nucleo_P87 PF07267.11 KKF96134.1 - 3 6.6 20.5 0.9 8.3 0.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 HTH_7 PF02796.15 KKF96135.1 - 4.5e-06 26.6 0.5 0.00026 21.0 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 KKF96135.1 - 8.1e-06 25.8 0.1 1.9e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KKF96135.1 - 0.00012 21.8 0.1 0.0003 20.5 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KKF96135.1 - 0.0029 17.7 0.2 0.0029 17.7 0.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 KKF96135.1 - 0.0055 17.3 0.4 0.0055 17.3 0.4 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_IS630 PF01710.16 KKF96135.1 - 0.0068 16.4 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Transposase TFIIA PF03153.13 KKF96135.1 - 0.0099 15.9 27.9 0.012 15.6 27.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit HTH_20 PF12840.7 KKF96135.1 - 0.026 14.6 0.2 0.065 13.3 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 KKF96135.1 - 0.03 14.0 0.0 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_22 PF13309.6 KKF96135.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_Tnp_ISL3 PF13542.6 KKF96135.1 - 0.15 11.5 0.2 0.15 11.5 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Presenilin PF01080.17 KKF96135.1 - 3 6.5 4.9 4.1 6.1 4.9 1.3 1 0 0 1 1 1 0 Presenilin DAO PF01266.24 KKF96136.1 - 7.1e-31 108.1 1.9 3.1e-25 89.5 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KKF96136.1 - 0.0041 16.4 0.0 0.0092 15.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KKF96136.1 - 0.0067 15.7 0.2 0.02 14.1 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKF96136.1 - 0.011 15.9 0.8 0.03 14.6 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KKF96136.1 - 0.037 13.3 1.5 0.055 12.8 0.1 2.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain ABC_tran PF00005.27 KKF96137.1 - 5.9e-44 149.9 0.0 3.4e-26 92.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKF96137.1 - 2.1e-37 129.3 15.2 2.1e-37 129.3 15.2 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KKF96137.1 - 7e-12 45.2 0.5 2.1e-05 24.1 0.6 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKF96137.1 - 2.9e-08 33.9 0.1 0.26 11.1 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKF96137.1 - 0.00019 21.9 0.0 0.016 15.6 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 KKF96137.1 - 0.0002 20.2 0.0 0.045 12.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KKF96137.1 - 0.0021 17.0 1.7 0.041 12.7 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 KKF96137.1 - 0.0036 17.0 0.1 0.015 15.0 0.1 2.1 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KKF96137.1 - 0.0066 16.7 0.3 0.078 13.3 0.2 2.6 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KKF96137.1 - 0.02 15.1 3.7 4 7.8 0.5 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KKF96137.1 - 0.038 14.5 0.2 0.068 13.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKF96137.1 - 0.04 13.6 0.1 0.35 10.6 0.0 2.6 2 2 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KKF96137.1 - 0.16 12.0 0.3 0.58 10.3 0.2 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKF96137.1 - 0.19 11.6 0.2 0.46 10.4 0.2 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KKF96137.1 - 0.26 11.8 0.6 1.5 9.3 0.6 2.4 1 1 0 1 1 1 0 AAA domain DUF983 PF06170.12 KKF96137.1 - 2.4 8.6 5.3 1.8 9.1 2.5 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF983) Polysacc_synt_4 PF04669.13 KKF96138.1 - 3.5e-23 82.2 0.5 1.4e-21 76.9 0.5 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis AChE_tetra PF08674.10 KKF96138.1 - 0.32 10.7 2.6 0.6 9.8 2.6 1.5 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain DUF3506 PF12014.8 KKF96139.1 - 2.7e-41 140.8 0.0 3.2e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) RTP801_C PF07809.11 KKF96139.1 - 0.04 13.8 0.0 0.082 12.8 0.0 1.4 2 0 0 2 2 2 0 RTP801 C-terminal region FAD_binding_2 PF00890.24 KKF96140.1 - 1.5e-43 149.4 0.2 2e-43 149.1 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Gpr1_Fun34_YaaH PF01184.19 KKF96141.1 - 2.6e-85 285.3 18.8 3.2e-85 285.0 18.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Collagen PF01391.18 KKF96142.1 - 9.8e-08 31.7 22.7 9.8e-08 31.7 22.7 3.1 3 0 0 3 3 3 2 Collagen triple helix repeat (20 copies) DUF3395 PF11875.8 KKF96143.1 - 8.3e-28 97.3 0.0 1.7e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KKF96143.1 - 8.7e-12 45.0 0.8 1.8e-11 44.0 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain NAD_binding_1 PF00175.21 KKF96144.1 - 4.6e-32 110.9 0.0 9.5e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKF96144.1 - 4.7e-23 81.4 0.0 8.1e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKF96144.1 - 4.1e-08 33.5 0.0 0.0013 18.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KKF96144.1 - 0.0032 17.7 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SH3_1 PF00018.28 KKF96145.1 - 2.4e-10 39.8 0.0 4.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKF96145.1 - 4.4e-09 36.1 0.1 8.2e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKF96145.1 - 0.00016 21.3 0.0 0.0007 19.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Ssu72 PF04722.13 KKF96146.1 - 1.8e-84 282.1 0.0 2e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.11 KKF96147.1 - 1.6e-15 56.4 0.2 1.1e-11 44.2 0.5 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT CENP-F_leu_zip PF10473.9 KKF96147.1 - 0.0038 17.3 31.2 0.01 15.9 16.5 3.2 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 KKF96147.1 - 0.0071 16.2 19.7 0.0071 16.2 19.7 2.6 2 1 1 3 3 3 1 Ezrin/radixin/moesin family Nup54_57_C PF18570.1 KKF96147.1 - 0.03 13.9 1.6 0.078 12.6 1.6 1.7 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain Filament PF00038.21 KKF96147.1 - 0.032 13.8 35.3 1.7 8.1 33.0 2.9 2 1 0 2 2 2 0 Intermediate filament protein HALZ PF02183.18 KKF96147.1 - 0.68 10.2 11.9 13 6.1 0.6 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper PSII_Pbs27 PF13326.6 KKF96147.1 - 2.5 8.4 7.9 1.9 8.8 1.0 2.5 2 0 0 2 2 2 0 Photosystem II Pbs27 GAS PF13851.6 KKF96147.1 - 2.6 7.4 30.6 14 5.0 13.5 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding BORCS7 PF16088.5 KKF96147.1 - 4.9 7.5 9.7 1.9 8.8 4.4 2.9 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 HHH_9 PF17674.1 KKF96147.1 - 7.5 7.5 6.8 2.7 9.0 0.1 3.4 3 1 1 4 4 4 0 HHH domain Peptidase_M28 PF04389.17 KKF96148.1 - 1e-21 77.6 0.1 4.2e-21 75.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.15 KKF96148.1 - 3.1e-20 72.5 0.0 5.8e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 KKF96148.1 - 9.7e-10 38.3 0.0 3.7e-09 36.5 0.0 2.0 1 0 0 1 1 1 1 PA domain A_amylase_inhib PF01356.19 KKF96148.1 - 0.022 14.8 0.5 0.13 12.3 0.0 2.5 3 0 0 3 3 3 0 Alpha amylase inhibitor Nicastrin PF05450.15 KKF96148.1 - 0.032 13.7 0.0 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 Nicastrin MFS_1 PF07690.16 KKF96149.1 - 2.3e-35 122.1 33.9 3.1e-26 92.1 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKF96149.1 - 1.5e-10 40.5 1.5 1.5e-10 40.5 1.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KKF96149.1 - 0.0032 16.0 0.4 0.0056 15.2 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3169 PF11368.8 KKF96149.1 - 0.0052 16.3 0.2 0.11 12.0 0.0 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3169) RET_CLD1 PF17756.1 KKF96149.1 - 0.15 12.4 0.0 0.49 10.7 0.0 1.8 2 0 0 2 2 2 0 RET Cadherin like domain 1 IMPDH PF00478.25 KKF96150.1 - 1.5e-123 412.2 5.5 1.8e-123 412.0 5.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KKF96150.1 - 2.4e-16 59.9 0.0 5.2e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 KKF96150.1 - 5e-07 29.4 4.3 0.0098 15.3 3.5 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 KKF96150.1 - 5.6e-07 28.9 1.0 1.5e-05 24.3 1.0 2.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KKF96150.1 - 0.00053 19.5 1.5 0.02 14.4 0.2 2.6 1 1 1 2 2 2 1 Histidine biosynthesis protein PK PF00224.21 KKF96150.1 - 0.041 12.8 0.0 0.53 9.1 0.0 2.4 2 1 0 2 2 2 0 Pyruvate kinase, barrel domain ThiG PF05690.14 KKF96150.1 - 0.066 12.5 0.3 0.15 11.3 0.3 1.6 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Prefoldin_3 PF13758.6 KKF96151.1 - 9.4e-23 80.1 0.4 2.7e-22 78.7 0.0 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 KKF96151.1 - 3.8e-20 72.5 0.8 3.8e-20 72.5 0.8 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3835) Peptidase_C26 PF07722.13 KKF96151.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase C26 UCR_Fe-S_N PF10399.9 KKF96151.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Spermine_synth PF01564.17 KKF96151.1 - 0.16 11.3 0.0 0.4 10.1 0.0 1.5 1 0 0 1 1 1 0 Spermine/spermidine synthase domain CS PF04969.16 KKF96152.1 - 6.8e-17 62.3 0.3 1.8e-16 60.9 0.0 1.8 3 0 0 3 3 3 1 CS domain Mei5_like PF17021.5 KKF96152.1 - 0.03 14.4 0.7 0.047 13.7 0.7 1.3 1 0 0 1 1 1 0 Putative double-strand recombination repair-like MAT1 PF06391.13 KKF96153.1 - 3.8e-32 111.8 6.8 5.5e-32 111.3 6.8 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KKF96153.1 - 1.2e-30 105.1 10.5 2.3e-30 104.3 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKF96153.1 - 0.001 18.9 5.6 0.0016 18.2 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKF96153.1 - 0.0032 17.3 5.6 0.009 15.9 5.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKF96153.1 - 0.018 15.4 5.8 0.03 14.6 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain Zn_ribbon_17 PF17120.5 KKF96153.1 - 0.076 12.7 1.2 0.15 11.7 1.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 KKF96153.1 - 0.098 12.8 2.7 0.21 11.7 2.7 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 KKF96153.1 - 0.1 12.5 7.3 0.47 10.3 7.5 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKF96153.1 - 0.12 12.3 9.0 1.3 9.1 9.5 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 KKF96153.1 - 0.66 9.8 10.8 5.5 6.9 11.4 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KKF96153.1 - 0.7 10.0 6.4 1.4 9.0 6.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger ANTH PF07651.16 KKF96154.1 - 7.8e-58 195.6 0.0 1.3e-57 195.0 0.0 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KKF96154.1 - 4.9e-08 33.1 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 ENTH domain Ribosomal_L23eN PF03939.13 KKF96154.1 - 0.027 14.7 0.5 0.066 13.4 0.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain TFIIA PF03153.13 KKF96154.1 - 2.1 8.2 30.7 3.1 7.7 30.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA-synt_2 PF00152.20 KKF96155.1 - 1.6e-43 149.0 0.0 2.1e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF3844 PF12955.7 KKF96156.1 - 1.4e-32 111.9 1.6 2.7e-32 111.0 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 KKF96156.1 - 3.8 8.0 11.4 10 6.6 11.4 1.8 1 1 0 1 1 1 0 EGF-like domain FliT PF05400.13 KKF96157.1 - 0.32 11.8 11.9 1.6 9.6 3.9 2.9 1 1 0 2 2 2 0 Flagellar protein FliT LSM PF01423.22 KKF96158.1 - 7.8e-20 70.3 0.1 8.7e-20 70.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain DHR-2 PF06920.13 KKF96159.1 - 0.031 12.9 0.2 0.055 12.1 0.0 1.4 2 0 0 2 2 2 0 Dock homology region 2 SNF2_N PF00176.23 KKF96160.1 - 1.3e-14 53.7 0.0 4.5e-13 48.7 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KKF96160.1 - 0.0016 17.8 1.2 0.16 11.3 0.0 3.6 4 0 0 4 4 4 1 C-5 cytosine-specific DNA methylase ResIII PF04851.15 KKF96160.1 - 0.0052 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_L44 PF00935.19 KKF96161.1 - 5.5e-36 122.9 12.6 8.9e-36 122.2 12.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 SH2_2 PF14633.6 KKF96163.1 - 4.2e-86 287.8 0.2 2.5e-85 285.3 0.1 2.2 2 0 0 2 2 2 1 SH2 domain HTH_44 PF14641.6 KKF96163.1 - 5.7e-35 120.2 0.5 2.2e-34 118.3 0.5 2.1 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 KKF96163.1 - 5.5e-32 110.2 0.0 1.2e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KKF96163.1 - 9.6e-31 106.6 0.0 1.4e-29 102.9 0.0 2.6 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KKF96163.1 - 2.2e-18 66.6 23.5 2.2e-18 66.6 23.5 6.1 7 1 1 8 8 8 1 Acidic N-terminal SPT6 SH2 PF00017.24 KKF96163.1 - 7.2e-05 22.8 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 KKF96163.1 - 0.00016 22.5 0.2 0.0013 19.6 0.2 2.8 1 1 0 1 1 1 1 HHH domain HHH_3 PF12836.7 KKF96163.1 - 0.00046 20.4 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 KKF96163.1 - 0.0094 16.3 0.5 0.024 15.0 0.5 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Tex_YqgF PF16921.5 KKF96163.1 - 0.15 12.6 0.0 0.45 11.0 0.0 1.9 1 0 0 1 1 1 0 Tex protein YqgF-like domain Pkinase PF00069.25 KKF96164.1 - 1.8e-64 217.7 0.0 2.4e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96164.1 - 1e-38 133.1 0.0 1.4e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKF96164.1 - 0.00015 20.7 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KKF96164.1 - 0.0041 16.5 0.0 0.0088 15.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KKF96164.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KKF96164.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HAD_2 PF13419.6 KKF96165.1 - 1.3e-12 48.2 0.0 3.9e-11 43.3 0.0 2.1 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKF96165.1 - 3.4e-12 47.1 0.0 8.6e-09 36.0 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKF96165.1 - 6.9e-07 29.3 0.2 1.2e-06 28.5 0.2 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KKF96165.1 - 2.3e-05 24.9 0.3 0.0033 17.9 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KKF96165.1 - 0.039 14.1 0.0 0.21 11.7 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HicB_lk_antitox PF15919.5 KKF96165.1 - 0.078 13.1 0.0 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system PGP_phosphatase PF09419.10 KKF96165.1 - 0.08 12.6 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase FUSC_2 PF13515.6 KKF96166.1 - 3.7e-26 91.7 5.5 3.7e-26 91.7 5.5 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 KKF96166.1 - 0.00023 19.9 5.5 0.00023 19.9 5.5 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein family Myb_DNA-bind_6 PF13921.6 KKF96166.1 - 0.15 12.3 0.0 0.65 10.3 0.0 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain Phage_holin_3_1 PF05106.12 KKF96166.1 - 0.15 12.5 3.8 0.74 10.3 2.9 2.7 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) ArAE_2 PF10334.9 KKF96166.1 - 0.18 11.6 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Aromatic acid exporter family member 2 ALMT PF11744.8 KKF96166.1 - 0.49 9.2 17.1 0.026 13.4 4.7 3.4 4 0 0 4 4 4 0 Aluminium activated malate transporter DNA_pol_E_B PF04042.16 KKF96167.1 - 8.7e-53 178.8 0.0 1.7e-52 177.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Gate PF07670.14 KKF96167.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Nucleoside recognition Pkinase PF00069.25 KKF96169.1 - 2.1e-74 250.2 0.0 2.9e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96169.1 - 9.6e-38 129.9 0.0 1.5e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KKF96169.1 - 7.6e-18 65.1 0.5 2.8e-10 40.7 0.1 2.8 2 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KKF96169.1 - 3.1e-13 49.6 0.3 6.7e-13 48.5 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KKF96169.1 - 3.2e-07 30.0 0.0 4.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KKF96169.1 - 0.00096 18.8 0.1 0.0017 18.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KKF96169.1 - 0.01 14.8 0.3 0.019 14.0 0.3 1.4 1 1 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 KKF96169.1 - 0.033 13.0 0.1 0.05 12.4 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 KKF96169.1 - 0.072 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKF96169.1 - 0.32 10.9 4.6 0.47 10.3 0.6 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Plasmodium_Vir PF05795.11 KKF96170.1 - 6.2 6.1 10.5 2.7 7.3 7.5 1.7 1 1 0 2 2 2 0 Plasmodium vivax Vir protein DUF1754 PF08555.10 KKF96171.1 - 3.9e-14 53.2 28.2 1.5e-10 41.8 16.2 2.3 2 0 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) DUF1027 PF06265.11 KKF96171.1 - 0.059 13.4 2.1 6.3 6.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) DUF4251 PF14059.6 KKF96171.1 - 0.16 11.9 2.2 2 8.4 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4251) Glutaredoxin2_C PF04399.13 KKF96171.1 - 0.18 11.7 0.5 0.32 10.8 0.5 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain AA_permease_2 PF13520.6 KKF96172.1 - 2.3e-58 198.1 35.3 1e-57 195.9 35.3 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKF96172.1 - 6.5e-18 64.6 39.3 1.5e-17 63.3 25.5 3.1 2 1 0 2 2 2 1 Amino acid permease GGN PF15685.5 KKF96172.1 - 0.63 9.0 3.4 0.87 8.6 3.4 1.1 1 0 0 1 1 1 0 Gametogenetin 2-Hacid_dh_C PF02826.19 KKF96173.1 - 2.9e-49 166.8 0.0 4.5e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKF96173.1 - 5.8e-15 55.1 0.0 8.5e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKF96173.1 - 0.00013 22.2 0.1 0.00036 20.7 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KKF96173.1 - 0.067 12.8 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain tRNA-synt_1g PF09334.11 KKF96174.1 - 2.7e-64 217.3 0.0 5.5e-63 213.0 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KKF96174.1 - 3.1e-08 32.4 0.1 0.00011 20.6 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKF96174.1 - 4.3e-06 26.8 0.3 1e-05 25.6 0.1 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KKF96174.1 - 0.014 14.8 0.0 0.066 12.6 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain NTF2 PF02136.20 KKF96175.1 - 0.0001 22.9 2.0 0.00063 20.3 2.0 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KKF96175.1 - 0.0056 16.6 0.1 0.016 15.2 0.1 1.7 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 PPTA PF01239.22 KKF96176.1 - 2.5e-38 128.7 18.3 6e-10 38.5 0.5 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat GHMP_kinases_N PF00288.26 KKF96177.1 - 9.6e-17 61.0 0.0 2.2e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKF96177.1 - 3.6e-10 40.1 0.0 8.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KKF96177.1 - 0.017 14.7 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Ribosomal_L38e PF01781.18 KKF96178.1 - 3.7e-33 113.5 3.1 4.2e-33 113.3 3.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Peptidase_M48_N PF16491.5 KKF96179.1 - 1.7e-61 207.3 8.5 1.7e-61 207.3 8.5 2.0 2 1 0 3 3 3 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KKF96179.1 - 2.6e-49 167.7 0.1 4.7e-49 166.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 Ribosomal_L34 PF00468.17 KKF96179.1 - 2.6e-11 43.3 11.8 2.6e-11 43.3 11.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L34 Peptidase_M56 PF05569.11 KKF96179.1 - 0.054 12.7 0.1 0.1 11.8 0.1 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 SprT-like PF10263.9 KKF96179.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 KKF96179.1 - 0.36 10.8 1.2 3 7.8 0.2 2.4 2 0 0 2 2 2 0 IrrE N-terminal-like domain DUF4538 PF15061.6 KKF96179.1 - 0.42 10.4 3.3 0.35 10.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Glyco_hydro_3_C PF01915.22 KKF96180.1 - 2e-45 155.3 0.0 5.1e-45 153.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKF96180.1 - 2e-41 142.4 0.0 3.2e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKF96180.1 - 1.2e-19 70.2 0.0 2.2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Lipase_3 PF01764.25 KKF96181.1 - 3.6e-29 101.5 0.0 5.8e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KKF96181.1 - 0.00021 21.2 0.2 0.00057 19.9 0.2 1.8 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_8 PF06259.12 KKF96181.1 - 0.0035 17.0 0.0 0.0088 15.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 KKF96181.1 - 0.006 17.2 0.2 0.0094 16.6 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KKF96181.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LRR_4 PF12799.7 KKF96182.1 - 2.2e-05 24.7 0.4 0.25 11.8 0.1 3.9 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KKF96182.1 - 0.046 13.8 3.7 8.4 6.7 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich repeat Vps39_2 PF10367.9 KKF96182.1 - 0.067 13.6 0.3 0.52 10.8 0.0 2.5 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 LRR_1 PF00560.33 KKF96182.1 - 0.11 13.1 0.4 48 5.1 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat SPX PF03105.19 KKF96182.1 - 0.31 10.9 2.5 0.4 10.5 2.5 1.1 1 0 0 1 1 1 0 SPX domain SNF2_N PF00176.23 KKF96183.1 - 1.6e-38 132.4 0.1 1.3e-32 112.9 0.0 3.0 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KKF96183.1 - 2.1e-14 53.8 0.0 8.4e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KKF96183.1 - 6.7e-07 29.1 5.8 6.7e-07 29.1 5.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKF96183.1 - 0.00018 21.3 6.9 0.00018 21.3 6.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKF96183.1 - 0.00095 19.5 8.2 0.00095 19.5 8.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKF96183.1 - 0.0017 18.2 6.1 0.0017 18.2 6.1 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KKF96183.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CIDR1_gamma PF18562.1 KKF96183.1 - 0.047 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma zf-RING_10 PF16685.5 KKF96183.1 - 8.1 6.7 13.5 0.53 10.5 3.6 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 FMO-like PF00743.19 KKF96184.1 - 9.9e-29 100.1 0.0 8.7e-16 57.4 0.0 3.0 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKF96184.1 - 9e-11 41.5 0.1 5e-10 39.1 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKF96184.1 - 2.6e-10 40.5 3.7 2.8e-07 30.6 0.2 4.4 3 2 1 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KKF96184.1 - 1.2e-09 37.8 0.1 7.9e-08 31.8 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KKF96184.1 - 3.3e-09 36.4 0.1 0.0002 20.7 0.2 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKF96184.1 - 1.8e-06 27.8 0.0 0.084 12.4 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KKF96184.1 - 7.4e-05 22.1 0.1 0.018 14.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Shikimate_DH PF01488.20 KKF96184.1 - 0.00086 19.4 0.0 0.069 13.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KKF96184.1 - 0.0017 18.5 0.0 0.0083 16.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KKF96184.1 - 0.016 14.6 0.0 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KKF96184.1 - 0.029 14.6 0.0 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 KKF96184.1 - 0.093 12.0 0.1 0.66 9.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain F420_oxidored PF03807.17 KKF96184.1 - 0.11 13.0 0.1 1.3 9.6 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KKF96184.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glu_dehyd_C PF16912.5 KKF96184.1 - 0.16 11.4 0.0 15 5.0 0.0 2.4 2 1 0 2 2 2 0 Glucose dehydrogenase C-terminus POT1 PF02765.17 KKF96185.1 - 3.9e-14 52.7 0.0 8.5e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 TFIIA PF03153.13 KKF96186.1 - 0.096 12.7 8.5 0.11 12.5 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KKF96186.1 - 8.1 6.0 8.1 12 5.4 8.1 1.2 1 0 0 1 1 1 0 Spt20 family GAS2 PF02187.17 KKF96187.1 - 1.5e-07 31.4 0.1 2.8e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Malic_M PF03949.15 KKF96188.1 - 6.2e-93 310.8 0.0 8.2e-93 310.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KKF96188.1 - 1.4e-71 240.1 0.0 2.5e-71 239.2 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TAP42 PF04177.12 KKF96189.1 - 2e-96 322.9 0.0 2.3e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family End3 PF12761.7 KKF96190.1 - 1.2e-75 254.1 5.3 1.6e-75 253.7 5.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KKF96190.1 - 2.2e-47 159.3 0.0 1.4e-46 156.7 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KKF96190.1 - 4.5e-07 29.0 0.2 1.1e-06 27.7 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KKF96190.1 - 3.1e-05 24.3 0.0 0.00012 22.4 0.0 2.1 2 0 0 2 2 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KKF96190.1 - 0.0013 18.5 0.2 0.0054 16.6 0.2 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KKF96190.1 - 0.0025 17.6 0.2 0.0061 16.4 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair DUF641 PF04859.12 KKF96190.1 - 0.015 15.6 2.5 0.015 15.6 2.5 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) EF-hand_5 PF13202.6 KKF96190.1 - 0.018 14.6 0.2 0.056 13.0 0.2 1.9 1 0 0 1 1 1 0 EF hand Atg14 PF10186.9 KKF96190.1 - 0.028 13.5 3.5 0.041 13.0 3.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlxA PF14282.6 KKF96190.1 - 0.086 12.8 8.4 2.6 8.1 3.7 2.3 1 1 1 2 2 2 0 FlxA-like protein COG5 PF10392.9 KKF96190.1 - 0.12 12.6 1.6 0.59 10.3 1.0 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 KxDL PF10241.9 KKF96190.1 - 0.12 12.6 3.3 0.18 12.1 0.3 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein COG2 PF06148.11 KKF96190.1 - 0.31 11.1 4.0 0.8 9.8 1.3 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 KKF96190.1 - 0.34 11.4 1.5 4.9 7.7 0.1 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IFT57 PF10498.9 KKF96190.1 - 0.36 9.8 5.9 1.3 7.9 0.6 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 PRP9_N PF16958.5 KKF96190.1 - 0.65 10.0 3.6 1.3 9.0 3.6 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus Spc7 PF08317.11 KKF96190.1 - 0.85 8.4 11.4 1.6 7.5 11.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Uds1 PF15456.6 KKF96190.1 - 1.4 9.1 7.7 3 8.0 7.7 1.5 1 1 0 1 1 1 0 Up-regulated During Septation Phage_GP20 PF06810.11 KKF96190.1 - 1.6 8.5 10.2 0.74 9.6 0.5 2.7 1 1 2 3 3 3 0 Phage minor structural protein GP20 Laminin_II PF06009.12 KKF96190.1 - 1.6 8.7 5.0 2.6 8.0 0.2 2.2 1 1 1 2 2 2 0 Laminin Domain II DHR10 PF18595.1 KKF96190.1 - 2.3 8.3 13.5 1.3 9.1 0.9 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Spectrin PF00435.21 KKF96190.1 - 3 8.4 9.7 11 6.6 8.1 2.4 2 1 0 2 2 1 0 Spectrin repeat SlyX PF04102.12 KKF96190.1 - 5.4 7.7 11.8 5.1 7.8 0.2 3.3 2 1 1 3 3 3 0 SlyX Snapin_Pallidin PF14712.6 KKF96190.1 - 6.1 7.3 7.4 3.1 8.3 1.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin DUF4407 PF14362.6 KKF96190.1 - 6.3 6.0 8.0 14 4.9 8.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 KKF96190.1 - 6.4 7.1 6.2 10 6.4 0.2 2.5 2 1 0 2 2 2 0 Haemolysin XhlA GrpE PF01025.19 KKF96190.1 - 7 6.3 13.1 1.3 8.7 0.7 2.3 1 1 1 2 2 2 0 GrpE Pyr_redox_2 PF07992.14 KKF96191.1 - 1.2e-36 126.5 0.1 1.5e-36 126.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKF96191.1 - 4.5e-09 36.8 1.0 6.6e-07 29.8 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKF96191.1 - 1.6e-06 27.5 0.4 0.046 12.8 0.0 3.8 4 1 1 5 5 5 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KKF96191.1 - 0.00012 22.1 0.2 6.2 6.8 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KKF96191.1 - 0.0035 16.6 0.3 0.41 9.9 0.2 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKF96191.1 - 0.017 14.3 0.6 4.5 6.5 0.0 2.9 2 1 1 3 3 3 0 Thi4 family NAD_binding_8 PF13450.6 KKF96191.1 - 0.025 14.8 0.2 6.6 7.1 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKF96191.1 - 0.029 13.1 0.9 14 4.2 0.0 3.5 3 1 1 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.19 KKF96191.1 - 0.039 13.2 1.6 11 5.2 0.0 3.1 4 0 0 4 4 4 0 FAD binding domain CoA_binding_2 PF13380.6 KKF96191.1 - 0.13 12.7 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain ACBP PF00887.19 KKF96192.1 - 2.2e-22 79.1 0.3 2.5e-22 78.9 0.3 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Thioredoxin PF00085.20 KKF96193.1 - 4.3e-43 145.5 0.7 3.4e-23 81.6 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KKF96193.1 - 2.3e-06 27.7 0.0 0.0094 15.9 0.0 3.8 3 1 1 4 4 4 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KKF96193.1 - 3.7e-06 27.0 0.1 0.034 14.3 0.1 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KKF96193.1 - 5.8e-06 26.6 3.8 0.067 13.5 0.1 4.7 4 2 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KKF96193.1 - 0.00079 19.8 4.2 0.18 12.2 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KKF96193.1 - 0.0019 18.1 0.5 0.78 9.7 0.0 3.1 3 0 0 3 3 3 1 AhpC/TSA family OST3_OST6 PF04756.13 KKF96193.1 - 0.024 14.0 0.1 9.9 5.4 0.0 2.8 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family Toxin_R_bind_N PF07953.12 KKF96193.1 - 0.053 13.2 1.2 0.11 12.2 1.2 1.5 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding Thioredoxin_3 PF13192.6 KKF96193.1 - 0.67 10.0 3.0 23 5.1 0.1 3.9 4 0 0 4 4 4 0 Thioredoxin domain PLDc_2 PF13091.6 KKF96194.1 - 2.1e-16 60.0 0.1 5.2e-07 29.6 0.0 3.7 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KKF96194.1 - 1e-09 38.2 1.6 0.00015 21.8 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Sec62 PF03839.16 KKF96195.1 - 1.1e-21 77.4 1.7 1.7e-21 76.7 0.0 2.0 1 1 1 2 2 2 1 Translocation protein Sec62 DUF1687 PF07955.11 KKF96195.1 - 2.6 8.5 4.8 8.8 6.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) DIM1 PF02966.16 KKF96196.1 - 3.3e-69 230.8 0.3 3.7e-69 230.6 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KKF96196.1 - 0.0011 18.9 0.1 0.0013 18.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KKF96196.1 - 0.084 13.2 0.8 0.14 12.5 0.8 1.4 1 1 0 1 1 1 0 Thioredoxin-like MOR2-PAG1_C PF14225.6 KKF96197.1 - 9.3e-84 281.2 1.3 3.9e-83 279.2 0.2 2.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KKF96197.1 - 3.9e-19 67.9 6.5 2e-14 52.3 0.1 3.7 2 1 2 4 4 4 3 Cell morphogenesis central region MOR2-PAG1_N PF14222.6 KKF96197.1 - 1.8e-12 47.1 0.0 9.5e-12 44.6 0.0 2.0 2 0 0 2 2 2 1 Cell morphogenesis N-terminal FAD_binding_1 PF00667.20 KKF96198.1 - 1.8e-62 210.8 0.0 2.4e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KKF96198.1 - 7e-21 74.9 0.0 1.4e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 KKF96198.1 - 1.7e-20 73.7 0.1 3.6e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin RRM_1 PF00076.22 KKF96199.1 - 1.4e-22 79.2 0.0 3.3e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KKF96199.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 WD40 PF00400.32 KKF96201.1 - 2.7e-54 179.9 23.0 1.3e-10 41.7 0.3 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF96201.1 - 6.8e-22 77.6 5.7 0.0001 22.5 0.1 6.0 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KKF96201.1 - 2.1e-19 70.1 0.0 4.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Patatin PF01734.22 KKF96201.1 - 3e-12 47.1 0.0 1e-11 45.4 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Ge1_WD40 PF16529.5 KKF96201.1 - 2.9e-08 33.1 4.4 0.0097 14.9 1.0 4.2 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KKF96201.1 - 0.00023 21.0 0.0 81 3.3 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Fibrinogen_aC PF12160.8 KKF96201.1 - 0.00045 20.0 0.7 68 3.4 0.0 5.3 4 1 1 5 5 5 0 Fibrinogen alpha C domain AAA_19 PF13245.6 KKF96201.1 - 0.0029 17.9 0.0 0.011 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF1986 PF09342.11 KKF96201.1 - 0.0033 17.8 2.7 30 5.0 0.0 4.5 2 2 2 4 4 4 0 Domain of unknown function (DUF1986) AAA_16 PF13191.6 KKF96201.1 - 0.014 15.8 0.0 0.11 12.9 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KKF96201.1 - 0.029 14.7 0.0 0.073 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Big_7 PF17957.1 KKF96201.1 - 0.04 14.7 5.4 15 6.4 0.0 4.9 5 0 0 5 5 5 0 Bacterial Ig domain AAA_11 PF13086.6 KKF96201.1 - 0.045 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Coatomer_WDAD PF04053.14 KKF96202.1 - 3.9e-172 573.3 0.0 4.6e-172 573.1 0.0 1.0 1 0 0 1 1 1 1 Coatomer WD associated region tRNA-synt_2 PF00152.20 KKF96205.1 - 3e-68 230.2 0.0 4.4e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KKF96205.1 - 9.2e-09 34.7 0.0 1.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KKF96205.1 - 3.7e-06 26.8 0.0 9.6e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KKF96205.1 - 0.01 15.3 0.1 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Abhydrolase_3 PF07859.13 KKF96206.1 - 6e-42 143.9 0.0 7.6e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKF96206.1 - 1.4e-06 27.5 0.1 4.2e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KKF96206.1 - 2.4e-05 25.0 2.2 0.0002 22.1 0.2 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKF96206.1 - 0.0079 16.0 0.0 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KKF96206.1 - 0.011 15.2 1.0 0.37 10.2 0.0 2.7 4 0 0 4 4 4 0 Prolyl oligopeptidase family Metallophos PF00149.28 KKF96207.1 - 1.8e-36 126.6 0.2 2.4e-36 126.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKF96207.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Rho_GDI PF02115.17 KKF96208.1 - 9.6e-66 221.3 0.3 1e-65 221.1 0.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP_dimer PF03717.15 KKF96208.1 - 0.089 13.1 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain KilA-N PF04383.13 KKF96209.1 - 2.8e-05 23.9 0.4 0.00015 21.6 0.0 2.3 2 1 1 3 3 3 1 KilA-N domain V_ATPase_I PF01496.19 KKF96209.1 - 2 6.2 6.3 2.7 5.8 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 KKF96209.1 - 9.3 5.4 6.2 14 4.8 6.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein NAD_binding_11 PF14833.6 KKF96210.1 - 1.7e-28 99.3 0.0 2.2e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KKF96210.1 - 1.1e-08 35.4 0.6 1.9e-08 34.6 0.6 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Phage-MuB_C PF09077.11 KKF96210.1 - 0.017 15.0 0.2 0.039 13.8 0.2 1.6 1 0 0 1 1 1 0 Mu B transposition protein, C terminal Adaptin_N PF01602.20 KKF96211.1 - 3e-79 267.0 0.4 2.3e-59 201.4 0.4 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KKF96211.1 - 4.5e-11 43.1 0.7 2.2e-10 40.8 0.1 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKF96211.1 - 1.5e-08 34.9 0.1 0.31 11.5 0.0 3.6 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 KKF96211.1 - 2.1e-07 30.6 0.4 0.028 14.6 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat Cohesin_HEAT PF12765.7 KKF96211.1 - 6.8e-05 23.1 0.4 0.02 15.2 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion MA3 PF02847.17 KKF96211.1 - 0.014 15.3 0.0 0.43 10.6 0.0 2.6 2 0 0 2 2 2 0 MA3 domain RNA_pol_3_Rpc31 PF11705.8 KKF96211.1 - 0.022 15.0 20.7 0.042 14.1 20.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CLASP_N PF12348.8 KKF96211.1 - 0.029 14.0 0.0 8 6.0 0.0 2.4 1 1 1 2 2 2 0 CLASP N terminal HEAT_EZ PF13513.6 KKF96211.1 - 0.062 13.8 0.4 11 6.7 0.1 2.9 2 0 0 2 2 2 0 HEAT-like repeat Nop14 PF04147.12 KKF96211.1 - 0.12 10.6 23.6 0.19 9.9 23.6 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KKF96211.1 - 0.32 10.3 18.8 0.52 9.6 18.8 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KKF96211.1 - 0.51 9.7 24.2 0.84 9.0 24.2 1.3 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 KKF96211.1 - 0.75 9.7 4.4 1.4 8.8 4.4 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPP4R2 PF09184.11 KKF96211.1 - 0.85 9.2 19.5 2.3 7.7 19.5 1.7 1 0 0 1 1 1 0 PPP4R2 Astro_capsid_p PF12226.8 KKF96211.1 - 2.2 7.3 20.1 4.6 6.3 20.1 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Na_trans_assoc PF06512.13 KKF96211.1 - 2.6 8.3 13.1 6.3 7.0 13.1 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated Cwf_Cwc_15 PF04889.12 KKF96211.1 - 5.2 6.7 27.3 0.41 10.4 22.4 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RVT_1 PF00078.27 KKF96212.1 - 2.3e-08 33.8 0.0 4.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2959 PF11172.8 KKF96212.1 - 0.00025 21.3 1.0 0.00055 20.1 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) Retrotrans_gag PF03732.17 KKF96212.1 - 0.0021 18.3 5.5 0.0056 16.9 0.0 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein DUF4294 PF14127.6 KKF96212.1 - 0.013 15.4 1.5 0.035 14.0 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) XhlA PF10779.9 KKF96212.1 - 0.017 15.3 0.4 0.035 14.3 0.4 1.5 1 0 0 1 1 1 0 Haemolysin XhlA MIF4G_like_2 PF09090.11 KKF96212.1 - 0.12 11.8 4.6 0.6 9.5 4.0 2.0 2 0 0 2 2 2 0 MIF4G like DUF2203 PF09969.9 KKF96212.1 - 0.79 10.5 4.7 2.1 9.1 4.7 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 KKF96212.1 - 0.81 10.0 10.6 2 8.8 10.6 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 KKF96212.1 - 0.98 9.5 3.1 2.2 8.3 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.10 KKF96212.1 - 1 9.2 3.4 7.1 6.5 0.2 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 PNMA PF14893.6 KKF96212.1 - 1.1 8.6 5.3 7.8 5.8 0.0 2.2 2 0 0 2 2 2 0 PNMA KfrA_N PF11740.8 KKF96212.1 - 1.1 9.9 7.3 0.41 11.3 3.4 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4404 PF14357.6 KKF96212.1 - 1.2 9.9 7.7 3.6 8.3 7.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Tup_N PF08581.10 KKF96212.1 - 6.4 7.2 13.8 8 6.8 10.0 2.4 2 0 0 2 2 2 0 Tup N-terminal Nuf2 PF03800.14 KKF96213.1 - 9.3e-42 142.4 0.2 3.7e-41 140.5 0.2 2.0 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KKF96213.1 - 2.3e-37 127.6 17.7 2.3e-37 127.6 17.7 3.9 3 2 1 4 4 4 1 Designed helical repeat protein 10 domain IFT46_B_C PF12317.8 KKF96213.1 - 1.7 8.3 13.8 0.049 13.4 6.6 2.0 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Ribosomal_S2 PF00318.20 KKF96214.1 - 2.8e-63 213.0 0.0 3.3e-62 209.5 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein S2 LDcluster4 PF18306.1 KKF96214.1 - 0.067 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 SLOG cluster4 family CBS PF00571.28 KKF96215.1 - 1.2e-34 118.5 10.4 4.3e-09 36.7 0.0 6.0 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 KKF96215.1 - 1.1e-08 34.9 1.2 1.9e-08 34.1 0.0 2.1 2 1 0 2 2 2 1 PB1 domain eIF2A PF08662.11 KKF96217.1 - 3.5e-73 245.6 0.0 7.5e-73 244.6 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KKF96217.1 - 0.032 15.1 0.1 19 6.4 0.0 4.0 3 1 0 4 4 4 0 WD domain, G-beta repeat Keratin_2_tail PF16210.5 KKF96217.1 - 8.8 6.6 14.5 0.52 10.6 6.4 2.2 2 0 0 2 2 2 0 Keratin type II cytoskeletal 1 tail Pkinase PF00069.25 KKF96218.1 - 1.1e-73 247.8 0.0 1.8e-73 247.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96218.1 - 1.7e-32 112.8 0.0 3.6e-32 111.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 KKF96218.1 - 1.7e-17 63.8 2.7 5.1e-09 36.6 0.5 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKF96218.1 - 9.2e-16 58.0 2.9 8.3e-08 32.6 0.1 3.2 3 0 0 3 3 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKF96218.1 - 1.1e-12 46.9 1.9 0.00018 21.6 0.0 4.8 5 0 0 5 5 4 2 Ankyrin repeat Ank_5 PF13857.6 KKF96218.1 - 1.7e-12 47.3 5.0 7.6e-05 22.9 0.1 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KKF96218.1 - 2.8e-12 46.5 9.4 5.2e-06 26.7 0.3 4.2 4 0 0 4 4 4 3 Ankyrin repeat Kinase-like PF14531.6 KKF96218.1 - 3.5e-06 26.6 0.0 5.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKF96218.1 - 0.0001 21.2 0.0 0.00023 20.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KKF96218.1 - 0.00056 19.9 0.5 0.0061 16.5 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KKF96218.1 - 0.00096 18.6 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.27 KKF96219.1 - 1.1e-16 60.5 0.0 2.4e-09 37.0 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein CVNH PF08881.10 KKF96220.1 - 6.5e-18 65.3 0.0 1.2e-17 64.4 0.0 1.4 1 1 1 2 2 2 1 CVNH domain DUF998 PF06197.13 KKF96221.1 - 0.0045 16.6 11.6 0.03 13.9 11.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF998) DUF308 PF03729.13 KKF96221.1 - 0.061 13.6 6.2 0.89 9.9 1.3 3.1 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) FAD_binding_4 PF01565.23 KKF96222.1 - 8e-11 41.8 1.7 1.7e-10 40.8 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKF96222.1 - 1.4e-10 41.1 0.2 2.8e-10 40.2 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KKF96222.1 - 0.015 14.7 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Pkinase PF00069.25 KKF96223.1 - 1.9e-28 99.6 0.0 4.1e-28 98.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96223.1 - 2.4e-10 40.1 0.0 2.3e-09 36.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PNP_phzG_C PF10590.9 KKF96224.1 - 6.1e-20 71.0 2.0 6.1e-20 71.0 2.0 2.3 3 0 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KKF96224.1 - 6.9e-18 64.6 0.0 1.2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KKF96224.1 - 0.0054 17.3 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M28 PF04389.17 KKF96225.1 - 4.5e-28 98.3 0.0 7e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KKF96225.1 - 3.3e-06 26.9 0.1 8.5e-06 25.6 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 AFG1_ATPase PF03969.16 KKF96226.1 - 4.7e-94 315.3 0.0 2.2e-89 299.9 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KKF96226.1 - 1e-05 26.0 0.1 0.056 13.8 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 KKF96226.1 - 0.0021 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 KKF96226.1 - 0.0026 17.6 0.2 0.26 11.1 0.1 2.4 2 1 0 2 2 2 1 Bacterial dnaA protein AAA PF00004.29 KKF96226.1 - 0.0036 17.7 0.0 0.0086 16.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKF96226.1 - 0.0056 17.0 0.0 0.047 14.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KKF96226.1 - 0.009 16.0 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF3606 PF12244.8 KKF96226.1 - 0.02 14.8 1.0 0.65 10.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) NACHT PF05729.12 KKF96226.1 - 0.076 12.9 0.0 0.46 10.4 0.0 2.3 2 1 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KKF96226.1 - 0.15 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KKF96226.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Metallophos PF00149.28 KKF96227.1 - 2.2e-31 110.0 0.2 1.8e-22 80.9 0.1 2.1 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KKF96227.1 - 0.015 15.7 0.4 0.037 14.5 0.4 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Cyclin_N PF00134.23 KKF96228.1 - 0.00046 19.9 0.1 0.0054 16.5 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain UCR_14kD PF02271.16 KKF96228.1 - 0.056 13.4 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit WD40 PF00400.32 KKF96229.1 - 1.8e-21 76.0 3.9 1.6e-05 25.5 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat DSPc PF00782.20 KKF96229.1 - 2e-09 37.4 0.1 8.6e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain ANAPC4_WD40 PF12894.7 KKF96229.1 - 9.6e-05 22.6 0.1 0.61 10.4 0.0 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KKF96229.1 - 0.014 15.4 0.0 0.56 10.3 0.0 3.1 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 KKF96229.1 - 0.036 14.3 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase Nup160 PF11715.8 KKF96229.1 - 0.056 12.1 0.9 1.9 7.0 0.1 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Init_tRNA_PT PF04179.12 KKF96229.1 - 0.081 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Kinesin PF00225.23 KKF96230.1 - 8.7e-106 353.6 0.6 8.7e-106 353.6 0.6 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KKF96230.1 - 3.6e-19 69.2 0.0 1.7e-18 67.0 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding HAP1_N PF04849.13 KKF96230.1 - 0.36 10.0 52.3 0.016 14.5 19.6 3.4 3 0 0 3 3 3 0 HAP1 N-terminal conserved region Alpha-mann_mid PF09261.11 KKF96230.1 - 4.4 7.5 9.9 0.15 12.2 0.4 3.5 2 2 1 3 3 3 0 Alpha mannosidase middle domain CENP-F_leu_zip PF10473.9 KKF96230.1 - 8.2 6.5 68.6 0.9 9.6 24.0 5.5 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ACPS PF01648.20 KKF96231.1 - 3.4e-05 23.9 0.0 4.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF1774 PF08611.10 KKF96232.1 - 6e-31 106.6 1.5 6e-31 106.6 1.5 3.0 3 1 0 4 4 4 1 Fungal protein of unknown function (DUF1774) AglB_L1 PF18079.1 KKF96233.1 - 0.072 13.4 0.0 2.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Archaeal glycosylation protein B long peripheral domain AAA_6 PF12774.7 KKF96234.1 - 3e-127 424.1 0.2 5.2e-126 420.0 0.0 3.2 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KKF96234.1 - 2.3e-117 392.5 4.8 2.3e-117 392.5 4.8 5.5 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 KKF96234.1 - 1.6e-112 377.0 5.1 1.6e-112 377.0 5.1 4.4 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 KKF96234.1 - 2.7e-73 245.7 0.2 1.6e-72 243.2 0.2 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KKF96234.1 - 8.7e-64 215.3 0.0 1.6e-62 211.2 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KKF96234.1 - 1.8e-40 138.3 0.0 4.8e-35 120.7 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KKF96234.1 - 4.1e-40 137.9 6.6 8.4e-40 136.8 6.6 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KKF96234.1 - 4.4e-32 111.0 0.2 9e-11 41.9 0.0 6.9 6 1 0 6 6 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KKF96234.1 - 2.3e-27 95.4 0.1 5.2e-26 91.1 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KKF96234.1 - 6.6e-27 94.3 0.0 1.6e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 KKF96234.1 - 6.2e-15 55.4 0.0 5.5e-14 52.4 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KKF96234.1 - 7e-15 55.5 1.1 0.0078 16.5 0.0 6.0 5 1 1 6 6 5 3 AAA domain AAA PF00004.29 KKF96234.1 - 1.2e-13 51.6 0.0 0.00036 20.9 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KKF96234.1 - 9.2e-09 35.6 1.8 0.49 10.6 0.1 5.2 5 0 0 5 5 4 3 AAA domain AAA_18 PF13238.6 KKF96234.1 - 2.6e-08 34.5 0.3 0.11 13.0 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KKF96234.1 - 4.9e-08 33.5 6.8 1.8 9.0 0.0 7.6 7 0 0 7 7 6 1 AAA ATPase domain AAA_29 PF13555.6 KKF96234.1 - 1.2e-05 25.0 0.1 0.87 9.4 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 KKF96234.1 - 3.4e-05 23.0 0.0 0.051 12.6 0.0 3.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_14 PF13173.6 KKF96234.1 - 7.3e-05 22.8 0.0 2.9 7.9 0.0 4.4 4 0 0 4 4 3 2 AAA domain AAA_lid_1 PF17857.1 KKF96234.1 - 0.00012 22.2 0.0 0.0006 20.0 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain ABC_tran PF00005.27 KKF96234.1 - 0.00015 22.3 0.1 5.3 7.6 0.0 4.5 3 0 0 3 3 3 0 ABC transporter Mg_chelatase PF01078.21 KKF96234.1 - 0.00015 21.2 0.8 0.68 9.3 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KKF96234.1 - 0.00047 19.8 0.9 0.4 10.2 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KKF96234.1 - 0.0034 17.1 0.5 17 5.0 0.0 4.5 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KKF96234.1 - 0.0044 16.4 0.0 2.4 7.5 0.0 3.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_19 PF13245.6 KKF96234.1 - 0.005 17.2 3.3 0.38 11.1 0.0 4.4 5 0 0 5 5 3 1 AAA domain IstB_IS21 PF01695.17 KKF96234.1 - 0.0056 16.4 0.3 0.56 9.9 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KKF96234.1 - 0.0099 16.3 0.1 28 5.1 0.0 4.5 4 0 0 4 4 4 0 RNA helicase Zeta_toxin PF06414.12 KKF96234.1 - 0.015 14.6 0.2 10 5.3 0.1 4.1 4 0 0 4 4 4 0 Zeta toxin NTPase_1 PF03266.15 KKF96234.1 - 0.054 13.4 0.0 19 5.1 0.0 3.8 3 0 0 3 3 3 0 NTPase Rad17 PF03215.15 KKF96234.1 - 0.084 12.8 0.1 7.6 6.4 0.0 3.4 4 0 0 4 4 2 0 Rad17 P-loop domain Mso1_Sec1_bdg PF14475.6 KKF96234.1 - 0.088 12.4 0.1 3.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Sec1-binding region of Mso1 AAA_30 PF13604.6 KKF96234.1 - 0.096 12.4 7.2 39 3.9 0.0 5.3 5 0 0 5 5 4 0 AAA domain RuvB_N PF05496.12 KKF96234.1 - 0.13 12.0 0.0 5.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MbeB_N PF04837.12 KKF96234.1 - 0.24 11.7 1.9 2.5 8.4 0.1 3.1 2 0 0 2 2 2 0 MbeB-like, N-term conserved region PspA_IM30 PF04012.12 KKF96234.1 - 0.52 9.9 37.0 0.0066 16.0 3.3 4.4 4 0 0 4 4 2 0 PspA/IM30 family DUF4482 PF14818.6 KKF96234.1 - 1.7 9.5 12.1 12 6.8 5.3 3.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4482) FliD_N PF02465.18 KKF96234.1 - 4.2 8.1 6.7 6.5 7.5 1.9 4.2 3 0 0 3 3 1 0 Flagellar hook-associated protein 2 N-terminus NACHT PF05729.12 KKF96234.1 - 7.6 6.4 8.6 31 4.4 0.0 4.6 5 0 0 5 5 4 0 NACHT domain Golgin_A5 PF09787.9 KKF96235.1 - 0.0003 20.4 1.2 0.00035 20.1 1.2 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Mt_ATP-synt_D PF05873.12 KKF96235.1 - 0.0031 17.4 1.0 0.0037 17.1 1.0 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) HIP1_clath_bdg PF16515.5 KKF96235.1 - 0.0081 16.8 3.6 0.014 16.0 3.6 1.3 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Syntaphilin PF15290.6 KKF96235.1 - 0.012 15.3 0.5 0.014 15.1 0.5 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Cas6 PF09559.10 KKF96235.1 - 0.067 13.1 0.1 0.087 12.8 0.1 1.2 1 0 0 1 1 1 0 Cas6 Crispr Med9 PF07544.13 KKF96235.1 - 0.068 13.3 4.5 0.45 10.6 4.6 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.20 KKF96235.1 - 0.068 13.1 6.0 0.11 12.4 6.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit EAP30 PF04157.16 KKF96235.1 - 0.089 12.1 0.4 0.12 11.6 0.4 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family PAP1 PF08601.10 KKF96236.1 - 0.79 9.4 39.2 1 9.0 39.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Vpu PF00558.19 KKF96236.1 - 2.3 8.0 8.9 0.53 10.1 5.2 1.9 1 1 1 2 2 2 0 Vpu protein EMP24_GP25L PF01105.24 KKF96237.1 - 6.3e-38 130.5 0.0 7e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RE_SacI PF09566.10 KKF96237.1 - 0.021 14.6 0.1 0.028 14.2 0.1 1.4 1 1 0 1 1 1 0 SacI restriction endonuclease RRXRR PF14239.6 KKF96237.1 - 0.097 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 RRXRR protein EzrA PF06160.12 KKF96237.1 - 0.13 10.5 1.3 0.17 10.0 1.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sdh5 PF03937.16 KKF96238.1 - 2.7e-25 88.1 0.5 5.8e-25 87.1 0.4 1.5 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase AP1AR PF15745.5 KKF96238.1 - 0.12 12.0 1.6 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 AP-1 complex-associated regulatory protein Aft1_HRR PF11787.8 KKF96239.1 - 1.3e-16 61.5 5.7 1.3e-16 61.5 5.7 3.8 4 1 0 4 4 4 1 Aft1 HRR domain bZIP_1 PF00170.21 KKF96239.1 - 2.1e-12 47.0 4.9 2.1e-12 47.0 4.9 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KKF96239.1 - 2.1e-07 30.9 4.0 2.1e-07 30.9 4.0 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KKF96239.1 - 0.0033 17.9 1.8 0.0033 17.9 1.8 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor HALZ PF02183.18 KKF96239.1 - 0.02 15.1 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper GIT_CC PF16559.5 KKF96239.1 - 0.033 14.1 0.7 0.083 12.8 0.7 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TolA_bind_tri PF16331.5 KKF96239.1 - 3 8.0 5.8 0.28 11.3 1.2 1.6 2 0 0 2 2 2 0 TolA binding protein trimerisation GST_N_3 PF13417.6 KKF96240.1 - 1.6e-08 34.8 0.9 6.8e-05 23.2 0.9 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKF96240.1 - 1.8e-07 31.1 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKF96240.1 - 4.1e-05 23.7 0.0 7.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKF96240.1 - 0.0016 18.7 0.1 0.047 14.0 0.0 2.5 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain CDT1_C PF16679.5 KKF96241.1 - 4.7e-16 59.0 3.2 8.6e-16 58.2 0.4 2.8 2 1 1 3 3 3 1 DNA replication factor Cdt1 C-terminal domain MBF1 PF08523.10 KKF96242.1 - 2e-26 92.2 0.6 3.3e-26 91.5 0.6 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KKF96242.1 - 3.4e-09 36.6 0.0 5.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KKF96242.1 - 0.0023 18.3 0.0 0.0093 16.3 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain GFA PF04828.14 KKF96244.1 - 1.3e-23 83.1 0.2 2.1e-23 82.5 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 KKF96244.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.6 3 0 0 3 3 3 0 Nudix N-terminal DZR PF12773.7 KKF96244.1 - 0.62 10.1 6.2 0.62 10.1 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon SpoU_methylase PF00588.19 KKF96245.1 - 2.3e-27 95.9 0.0 3.7e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KKF96245.1 - 4.3e-09 36.5 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Proteasome PF00227.26 KKF96246.1 - 7.8e-55 185.3 0.1 1.2e-54 184.6 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Zn_clus PF00172.18 KKF96246.1 - 2.8e-07 30.5 11.2 5.1e-07 29.7 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome_A_N PF10584.9 KKF96246.1 - 0.00057 19.5 0.0 0.00057 19.5 0.0 2.2 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature zf-CHY PF05495.12 KKF96247.1 - 2.4e-12 47.2 19.9 4.1e-12 46.4 19.9 1.4 1 0 0 1 1 1 1 CHY zinc finger RNA_POL_M_15KD PF02150.16 KKF96247.1 - 0.44 10.5 10.4 3.3 7.7 0.5 3.3 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit Zn_Tnp_IS91 PF14319.6 KKF96247.1 - 5.2 7.2 15.3 0.79 9.8 4.7 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain HypA PF01155.19 KKF96247.1 - 7.5 6.6 13.0 8.1 6.5 10.5 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TrkH PF02386.16 KKF96248.1 - 3.1e-44 151.3 15.7 1.1e-43 149.4 10.7 2.8 2 1 0 2 2 2 2 Cation transport protein SRP-alpha_N PF04086.13 KKF96248.1 - 0.016 15.2 3.1 0.031 14.2 3.1 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_L19 PF01245.20 KKF96249.1 - 1.3e-09 37.9 0.0 2.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 PALP PF00291.25 KKF96251.1 - 2.1e-56 191.5 1.5 1.9e-34 119.5 0.2 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme zf-C3HC4 PF00097.25 KKF96252.1 - 3.8e-08 33.1 4.0 2.3e-07 30.6 4.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KKF96252.1 - 6.5e-08 32.3 1.1 1.6e-07 31.1 0.6 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 KKF96252.1 - 6.6e-08 32.4 3.6 6.6e-08 32.4 3.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KKF96252.1 - 4.2e-07 30.2 4.8 9.2e-07 29.1 4.8 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KKF96252.1 - 1.4e-06 28.1 2.6 3e-06 27.1 2.6 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KKF96252.1 - 1.5e-06 27.9 3.3 1.5e-06 27.9 3.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KKF96252.1 - 4e-05 23.7 4.7 0.00017 21.7 4.8 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KKF96252.1 - 6.3e-05 22.8 3.9 0.0016 18.3 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KKF96252.1 - 0.00074 19.6 1.0 0.0055 16.8 0.6 2.0 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KKF96252.1 - 0.034 14.0 4.8 0.69 9.8 4.8 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 XRN1_D2_D3 PF18334.1 KKF96252.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Exoribonuclease Xrn1 D2/D3 domain IBR PF01485.21 KKF96252.1 - 0.46 10.7 4.5 47 4.3 0.0 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-rbx1 PF12678.7 KKF96252.1 - 2.4 8.5 7.4 4.1 7.8 4.0 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger domain ECH_1 PF00378.20 KKF96253.1 - 1e-71 241.2 0.5 1.1e-71 241.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKF96253.1 - 3.6e-34 118.8 0.9 4.5e-31 108.6 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HA70_C PF17993.1 KKF96253.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain Rer1 PF03248.13 KKF96254.1 - 2.1e-76 255.4 3.8 2.5e-76 255.2 3.8 1.0 1 0 0 1 1 1 1 Rer1 family DUF4131 PF13567.6 KKF96254.1 - 1.2 8.8 7.7 3 7.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Mus7 PF09462.10 KKF96255.1 - 4.4e-37 128.3 0.1 3.4e-22 79.1 0.0 2.2 1 1 1 2 2 2 2 Mus7/MMS22 family AAA PF00004.29 KKF96255.1 - 9.6e-37 126.4 0.0 7.4e-36 123.5 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKF96255.1 - 5.1e-10 39.0 0.3 1.9e-09 37.2 0.3 2.0 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KKF96255.1 - 1e-05 25.4 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKF96255.1 - 4.5e-05 23.9 1.8 0.0037 17.6 0.0 3.9 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KKF96255.1 - 9e-05 22.8 1.3 0.19 12.0 0.1 3.8 2 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KKF96255.1 - 0.004 17.3 0.0 0.079 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKF96255.1 - 0.016 15.0 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KKF96255.1 - 0.034 14.7 0.0 0.13 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KKF96255.1 - 0.036 13.5 0.0 0.94 8.9 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 KKF96255.1 - 0.068 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KKF96255.1 - 0.07 13.5 0.1 0.24 11.8 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Mg_chelatase PF01078.21 KKF96255.1 - 0.12 11.7 0.1 0.3 10.4 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KKF96255.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KKF96255.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain BSD PF03909.17 KKF96256.1 - 9.4e-30 102.4 5.5 1.5e-15 56.9 0.2 3.0 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 KKF96256.1 - 2.5e-24 85.4 0.0 1.1e-23 83.4 0.0 2.1 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Transket_pyr PF02779.24 KKF96257.1 - 2.3e-63 213.1 0.1 4.6e-63 212.1 0.1 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KKF96257.1 - 1.4e-60 204.8 0.0 2.2e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KKF96257.1 - 1.9e-57 193.2 0.0 3e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KKF96257.1 - 3.2e-18 65.0 0.9 6.3e-18 64.1 0.9 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus WD40 PF00400.32 KKF96258.1 - 3.6e-23 81.4 14.9 5.1e-08 33.4 0.1 7.0 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF96258.1 - 0.0015 18.8 5.2 7.3 7.0 0.0 5.1 6 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF96258.1 - 0.0018 17.3 0.4 0.19 10.6 0.0 3.1 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RasGEF PF00617.19 KKF96259.1 - 7.4e-60 202.2 0.1 1.7e-59 201.0 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KKF96259.1 - 5.2e-29 100.6 0.9 1.4e-28 99.2 0.9 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KKF96259.1 - 9.3e-15 54.0 0.1 2.5e-14 52.6 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKF96259.1 - 1.1e-13 50.8 0.1 2.4e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKF96259.1 - 1e-12 47.5 0.0 2.2e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SCA7 PF08313.12 KKF96260.1 - 3.4e-31 106.9 0.2 1.3e-30 105.1 0.2 2.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain Presenilin PF01080.17 KKF96260.1 - 1.6 7.4 6.6 2.4 6.9 6.6 1.2 1 0 0 1 1 1 0 Presenilin zf-NOSIP PF15906.5 KKF96261.1 - 9.2e-08 32.1 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 KKF96261.1 - 2e-05 24.5 9.0 0.00016 21.6 0.9 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 KKF96261.1 - 4.4e-05 23.7 15.2 0.00023 21.4 3.9 2.6 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 KKF96261.1 - 6.9e-05 22.7 3.9 6.9e-05 22.7 3.9 2.6 2 0 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.12 KKF96261.1 - 0.00085 18.8 0.3 0.00085 18.8 0.3 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 KKF96261.1 - 0.0022 17.9 16.3 0.012 15.5 3.8 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKF96261.1 - 0.0046 16.8 17.6 0.13 12.2 4.8 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKF96261.1 - 0.0078 16.0 2.4 0.0078 16.0 2.4 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KKF96261.1 - 0.1 12.8 12.3 0.99 9.6 4.1 3.4 2 1 1 3 3 3 0 FYVE zinc finger TAtT PF16811.5 KKF96261.1 - 0.35 10.1 1.3 0.55 9.5 1.3 1.2 1 0 0 1 1 1 0 TRAP transporter T-component TMPIT PF07851.13 KKF96261.1 - 0.38 10.0 0.4 0.54 9.5 0.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein CMS1 PF14617.6 KKF96261.1 - 0.88 8.9 3.9 1.3 8.3 3.9 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Acyltransferase PF01553.21 KKF96262.1 - 2.2e-16 59.7 0.0 3.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 KKF96263.1 - 5.4e-70 235.8 0.0 1.2e-69 234.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96263.1 - 1.4e-32 113.1 0.0 3.4e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKF96263.1 - 0.096 11.6 0.0 0.096 11.6 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain TFIIA PF03153.13 KKF96263.1 - 3.1 7.7 46.2 5.4 6.9 46.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 KKF96263.1 - 4 7.2 19.7 6.6 6.5 19.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAP_central PF04928.17 KKF96265.1 - 9.7e-110 365.4 0.0 1.3e-109 364.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KKF96265.1 - 1.9e-58 196.9 1.8 8.7e-58 194.7 1.8 1.9 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KKF96265.1 - 1.3e-09 38.3 0.0 2.9e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KKF96265.1 - 0.036 14.2 0.1 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 KKF96265.1 - 0.075 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Tubulin_3 PF14881.6 KKF96266.1 - 4.4e-43 147.0 0.0 8.1e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain CTP_synth_N PF06418.14 KKF96267.1 - 3.5e-114 380.6 0.2 6.6e-114 379.7 0.2 1.4 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KKF96267.1 - 1.3e-55 188.1 0.0 2e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKF96267.1 - 4.4e-06 26.6 0.0 1.2e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 CLU PF13236.6 KKF96268.1 - 1.9e-75 253.5 0.0 3.4e-75 252.7 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KKF96268.1 - 2.4e-48 164.5 1.2 2.7e-48 164.3 0.0 1.8 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KKF96268.1 - 2.1e-29 101.6 7.9 4.8e-14 52.4 0.4 4.7 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KKF96268.1 - 1.9e-25 88.0 2.0 5e-07 29.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.6 KKF96268.1 - 2.8e-22 78.9 0.1 1e-21 77.0 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_8 PF13181.6 KKF96268.1 - 3.6e-05 23.6 5.6 1.2 9.5 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKF96268.1 - 0.021 14.9 15.5 0.5 10.6 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF727 PF05303.12 KKF96268.1 - 0.025 14.7 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF727) TPR_1 PF00515.28 KKF96268.1 - 0.11 12.3 3.8 19 5.2 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat FancD2 PF14631.6 KKF96268.1 - 0.84 6.9 4.1 1.3 6.3 4.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease CDC45 PF02724.14 KKF96268.1 - 1.9 6.7 7.1 2.8 6.1 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 KKF96268.1 - 3.7 7.4 12.2 12 5.8 12.2 1.9 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3391 PF11871.8 KKF96268.1 - 4.7 7.8 7.9 5.6 7.5 5.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Vfa1 PF08432.10 KKF96268.1 - 7.1 6.9 14.8 19 5.5 14.8 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Forkhead PF00250.18 KKF96269.1 - 2.5e-27 94.9 0.1 5e-27 94.0 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KKF96269.1 - 6.6e-11 42.4 0.0 1.9e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 FHA domain Linker_histone PF00538.19 KKF96269.1 - 0.091 13.1 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 linker histone H1 and H5 family Aldo_ket_red PF00248.21 KKF96270.1 - 4.6e-40 137.6 0.0 7.1e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_3 PF07859.13 KKF96270.1 - 0.014 15.3 0.1 0.29 11.0 0.1 2.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold RR_TM4-6 PF06459.12 KKF96271.1 - 0.012 15.5 17.1 0.03 14.2 17.1 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KKF96271.1 - 6.2 5.5 29.5 15 4.2 29.5 1.6 1 0 0 1 1 1 0 Presenilin CH PF00307.31 KKF96272.1 - 1.9e-46 156.7 0.2 6.6e-23 81.0 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KKF96272.1 - 5.5e-25 87.3 1.2 2.1e-24 85.4 0.1 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KKF96272.1 - 2.7e-11 43.2 1.9 1.1e-06 28.3 0.1 3.0 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.6 KKF96272.1 - 0.0006 19.5 0.1 0.0032 17.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KKF96272.1 - 0.0011 19.3 1.4 0.0041 17.5 1.4 2.1 1 0 0 1 1 1 1 EF-hand domain pair Prim-Pol PF09250.11 KKF96272.1 - 0.015 15.6 0.1 0.032 14.6 0.1 1.5 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal EF-hand_8 PF13833.6 KKF96272.1 - 0.053 13.4 0.3 0.45 10.4 0.1 2.6 2 1 1 3 3 3 0 EF-hand domain pair FAD-oxidase_C PF02913.19 KKF96273.1 - 2.6e-62 210.7 0.0 4e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KKF96273.1 - 1.1e-37 128.9 0.6 2.2e-37 127.9 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain Turandot PF07240.11 KKF96273.1 - 0.038 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot zf-CCHC PF00098.23 KKF96275.1 - 0.00051 20.0 1.5 0.00095 19.1 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Arena_nucleocap PF00843.17 KKF96275.1 - 0.0057 15.6 0.0 0.0077 15.2 0.0 1.1 1 0 0 1 1 1 1 Arenavirus nucleocapsid N-terminal domain zf-C2H2_10 PF16588.5 KKF96275.1 - 0.028 14.1 1.3 0.049 13.4 1.3 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_5 PF14787.6 KKF96275.1 - 0.037 13.7 4.3 0.037 13.7 4.3 1.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger TMEM95 PF15203.6 KKF96275.1 - 0.066 12.9 0.1 0.43 10.2 0.2 2.1 2 0 0 2 2 2 0 TMEM95 family bPH_4 PF06713.11 KKF96275.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain CDC14 PF08045.11 KKF96276.1 - 1e-123 412.0 0.0 1.1e-123 411.8 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.17 KKF96277.1 - 3.5e-65 219.6 0.0 5.1e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Pex24p PF06398.11 KKF96278.1 - 7.6e-82 275.2 0.0 1.1e-81 274.7 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Metal_resist PF13801.6 KKF96278.1 - 0.01 16.0 0.1 0.45 10.7 0.0 2.3 2 0 0 2 2 2 0 Heavy-metal resistance LisH_2 PF16045.5 KKF96278.1 - 0.066 12.2 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 LisH Pkinase PF00069.25 KKF96279.1 - 1.3e-51 175.6 0.0 1.9e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96279.1 - 2.5e-19 69.6 0.0 5.7e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKF96279.1 - 0.0042 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKF96279.1 - 0.098 12.2 0.9 0.24 10.9 0.9 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box PF00646.33 KKF96280.1 - 0.013 15.4 0.1 0.042 13.7 0.1 2.0 1 0 0 1 1 1 0 F-box domain TPR_12 PF13424.6 KKF96280.1 - 0.089 13.1 0.4 4.5 7.6 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 KKF96280.1 - 3 7.8 6.9 7.4 6.6 0.1 3.6 3 1 0 3 3 3 0 F-box-like ADIP PF11559.8 KKF96282.1 - 5.4e-23 81.8 10.8 5.1e-12 46.1 7.0 2.9 2 1 1 3 3 2 2 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KKF96282.1 - 2.9e-05 23.7 1.2 6.6e-05 22.5 1.2 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 5 Spc7 PF08317.11 KKF96282.1 - 0.00095 18.1 1.4 0.0022 17.0 0.8 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF4686 PF15742.5 KKF96282.1 - 0.015 14.4 0.9 0.028 13.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) Csm1_N PF18504.1 KKF96282.1 - 0.092 13.1 2.5 60 4.1 0.0 3.6 2 1 1 3 3 3 0 Csm1 N-terminal domain Phage_GP20 PF06810.11 KKF96282.1 - 0.1 12.4 0.9 4.4 7.1 0.1 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 FmiP_Thoc5 PF09766.9 KKF96282.1 - 0.13 11.5 0.6 0.26 10.6 0.6 1.4 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 DegS PF05384.11 KKF96282.1 - 0.14 11.6 2.7 0.36 10.3 2.7 1.7 1 0 0 1 1 1 0 Sensor protein DegS DUF641 PF04859.12 KKF96282.1 - 0.17 12.3 7.5 0.66 10.3 1.7 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.12 KKF96282.1 - 0.31 11.1 8.2 0.11 12.6 4.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KKF96282.1 - 0.35 10.9 4.4 0.36 10.8 2.7 2.0 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 KKF96282.1 - 0.47 10.5 6.8 0.21 11.6 2.4 2.5 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 KKF96282.1 - 1.3 9.5 4.7 0.72 10.4 1.6 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 KKF96282.1 - 2.2 8.7 10.4 4 7.8 6.5 2.5 2 1 1 3 3 3 0 Fez1 Syntaxin-6_N PF09177.11 KKF96282.1 - 2.7 8.6 6.7 0.75 10.4 1.7 2.6 3 0 0 3 3 2 0 Syntaxin 6, N-terminal RRP7 PF12923.7 KKF96283.1 - 1.9e-31 108.7 11.2 1.9e-31 108.7 11.2 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KKF96283.1 - 1.2e-10 41.4 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain L_HMGIC_fpl PF10242.9 KKF96284.1 - 4.1 7.6 9.7 5.4 7.2 9.7 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein IF4E PF01652.18 KKF96285.1 - 6.5e-38 130.0 0.6 8.5e-38 129.6 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E EF-hand_6 PF13405.6 KKF96286.1 - 0.019 14.9 0.0 22 5.3 0.0 4.0 3 2 0 3 3 3 0 EF-hand domain Kinesin PF00225.23 KKF96287.1 - 6.6e-110 367.1 0.0 1.1e-109 366.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKF96287.1 - 3e-22 79.2 0.0 8.7e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Spc7 PF08317.11 KKF96287.1 - 0.025 13.4 5.7 0.044 12.7 5.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KKF96287.1 - 0.1 13.1 0.7 0.26 11.8 0.7 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SIKE PF05769.11 KKF96287.1 - 0.12 12.2 10.7 0.019 14.9 6.3 2.0 2 0 0 2 2 2 0 SIKE family DUF2018 PF09442.10 KKF96287.1 - 0.61 11.1 4.6 3 8.9 1.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) HA2 PF04408.23 KKF96288.1 - 1.3e-16 60.8 4.2 1.1e-15 57.8 0.0 3.6 4 0 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKF96288.1 - 6.1e-16 58.6 0.0 1.4e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKF96288.1 - 1.6e-13 51.0 0.0 3.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKF96288.1 - 5.5e-10 39.3 0.1 1.7e-09 37.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.22 KKF96288.1 - 5.1e-06 26.8 0.4 9.6e-06 25.9 0.4 1.5 1 0 0 1 1 1 1 RWD domain DND1_DSRM PF14709.7 KKF96288.1 - 0.0007 19.8 0.0 0.0021 18.3 0.0 1.9 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.6 KKF96288.1 - 0.0047 17.2 1.4 0.038 14.3 1.2 2.5 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KKF96288.1 - 0.011 14.8 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KKF96288.1 - 0.015 15.0 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KKF96288.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC dsRBD2 PF17842.1 KKF96288.1 - 0.021 15.0 0.0 0.058 13.6 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 ResIII PF04851.15 KKF96288.1 - 0.067 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit XRN1_D1 PF18332.1 KKF96288.1 - 0.085 12.6 0.1 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D1 domain PhoH PF02562.16 KKF96288.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 KKF96288.1 - 0.13 12.7 0.6 0.69 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain dsrm PF00035.26 KKF96288.1 - 6 7.7 5.7 0.88 10.3 0.2 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif Arm PF00514.23 KKF96289.1 - 1.8e-95 310.4 15.8 9.1e-13 47.8 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KKF96289.1 - 1.9e-27 95.5 0.4 1.9e-27 95.5 0.4 1.8 2 0 0 2 2 1 1 Importin beta binding domain Arm_3 PF16186.5 KKF96289.1 - 1.8e-24 85.0 3.8 4.1e-24 83.9 3.8 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KKF96289.1 - 8e-20 70.9 9.6 1.3e-06 28.8 0.2 6.4 5 1 1 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.6 KKF96289.1 - 2.1e-18 66.5 0.3 2.7e-07 30.9 0.1 5.4 1 1 4 5 5 5 4 HEAT repeats HEAT PF02985.22 KKF96289.1 - 1e-16 59.6 3.2 0.0011 19.1 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 KKF96289.1 - 1.2e-07 31.5 0.0 0.011 15.2 0.0 4.1 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 KKF96289.1 - 6.5e-05 21.7 0.0 0.0047 15.5 0.0 2.3 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KKF96289.1 - 0.00012 22.2 0.0 0.81 9.8 0.0 4.4 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 KKF96289.1 - 0.00085 19.8 0.2 1.9 9.4 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 KKF96289.1 - 0.029 14.6 4.9 17 5.7 0.0 5.0 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.17 KKF96289.1 - 0.051 13.4 0.0 7.2 6.5 0.0 3.3 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain NopRA1 PF16201.5 KKF96289.1 - 0.053 13.1 0.0 13 5.3 0.0 3.7 2 2 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 NUSAP PF16006.5 KKF96289.1 - 3.1 7.5 6.2 4.5 7.0 6.2 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein STAG PF08514.11 KKF96290.1 - 8.8e-27 93.3 0.1 4.7e-26 90.9 0.0 2.3 2 0 0 2 2 2 1 STAG domain Cnd1 PF12717.7 KKF96290.1 - 3.5e-05 23.9 4.2 0.069 13.2 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RNA_pol_Rpc4 PF05132.14 KKF96291.1 - 6.7e-27 94.8 0.0 6.7e-27 94.8 0.0 3.0 2 1 0 2 2 2 1 RNA polymerase III RPC4 DUF1943 PF09172.11 KKF96291.1 - 0.16 11.2 1.2 0.22 10.7 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Cyclin_N PF00134.23 KKF96293.1 - 9.3e-41 138.5 0.1 1.9e-40 137.5 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKF96293.1 - 7.3e-32 109.9 0.0 1.3e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pyocin_S PF06958.12 KKF96293.1 - 0.16 12.5 0.3 0.33 11.5 0.3 1.5 1 0 0 1 1 1 0 S-type Pyocin DUF3362 PF11842.8 KKF96293.1 - 2.2 8.6 6.7 1.2 9.4 4.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3362) Ribosomal_L2 PF00181.23 KKF96294.1 - 1.9e-24 85.4 0.8 3.6e-24 84.5 0.8 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C PF03947.18 KKF96294.1 - 2.6e-15 56.7 0.1 8.9e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain SR-25 PF10500.9 KKF96295.1 - 3.4 7.2 7.8 3.8 7.1 7.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HMG_box PF00505.19 KKF96296.1 - 9.5e-07 29.1 0.0 2.4e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKF96296.1 - 0.051 14.2 0.0 0.095 13.3 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain MATalpha_HMGbox PF04769.12 KKF96296.1 - 0.055 12.8 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 HMG-box AP_endonuc_2_N PF07582.12 KKF96296.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus BAR PF03114.18 KKF96299.1 - 9.4e-67 225.1 8.1 1.1e-66 224.8 8.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KKF96299.1 - 4.3e-14 51.9 0.0 1e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKF96299.1 - 8.7e-12 44.7 0.1 1.6e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKF96299.1 - 4.2e-10 39.2 0.4 1.1e-09 37.8 0.0 2.0 3 0 0 3 3 3 1 Variant SH3 domain Vps5 PF09325.10 KKF96299.1 - 0.24 10.9 6.1 1.2 8.6 2.5 2.2 2 0 0 2 2 2 0 Vps5 C terminal like TMPIT PF07851.13 KKF96299.1 - 0.87 8.8 8.9 0.66 9.2 0.1 2.3 1 1 1 2 2 2 0 TMPIT-like protein Aminotran_5 PF00266.19 KKF96300.1 - 3.6e-91 305.9 0.0 4.3e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KKF96300.1 - 1.9e-05 24.1 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KKF96300.1 - 0.026 13.8 0.0 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family CsbD PF05532.12 KKF96301.1 - 5.1e-06 26.3 16.6 5.9e-06 26.1 7.6 2.9 2 1 0 2 2 2 2 CsbD-like HMG_box PF00505.19 KKF96304.1 - 1.4e-10 41.4 0.3 4.7e-10 39.8 0.3 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKF96304.1 - 0.0064 17.1 0.2 0.014 16.0 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KKF96304.1 - 0.084 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Adap_comp_sub PF00928.21 KKF96305.1 - 3.1e-20 72.6 0.0 4.2e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pribosyl_synth PF14572.6 KKF96306.1 - 1.6e-31 109.8 0.1 2.6e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KKF96306.1 - 9.8e-05 21.9 0.1 0.00015 21.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain COMPASS-Shg1 PF05205.12 KKF96306.1 - 0.073 13.8 0.1 0.15 12.8 0.1 1.6 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 UPRTase PF14681.6 KKF96306.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase adh_short PF00106.25 KKF96307.1 - 1.7e-30 106.0 0.3 2.3e-30 105.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF96307.1 - 3.8e-20 72.4 0.1 2.9e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF96307.1 - 2.6e-12 47.0 0.0 4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKF96307.1 - 0.0068 15.6 0.1 0.011 14.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KKF96307.1 - 0.0078 16.5 0.1 0.013 15.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KKF96307.1 - 0.015 14.7 0.1 0.042 13.3 0.0 1.7 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family RNA_pol_Rpb8 PF03870.15 KKF96308.1 - 9.5e-44 149.0 0.1 1.1e-43 148.8 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Anp1 PF03452.14 KKF96309.1 - 2.3e-112 374.7 1.4 1.8e-111 371.8 0.0 2.0 2 0 0 2 2 2 1 Anp1 Rad54_N PF08658.10 KKF96309.1 - 0.071 13.3 1.9 0.13 12.4 1.9 1.4 1 0 0 1 1 1 0 Rad54 N terminal Ferlin_C PF16165.5 KKF96309.1 - 2.3 8.1 3.9 4.9 7.1 3.9 1.5 1 0 0 1 1 1 0 Ferlin C-terminus Sec7 PF01369.20 KKF96310.1 - 3.1e-39 134.5 0.4 5.8e-39 133.7 0.4 1.4 1 0 0 1 1 1 1 Sec7 domain RRM_1 PF00076.22 KKF96311.1 - 4.2e-25 87.4 0.3 1e-11 44.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKF96311.1 - 8.1e-05 22.4 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KKF96311.1 - 8.6e-05 22.1 0.0 0.0048 16.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KKF96311.1 - 0.019 14.8 0.0 0.065 13.0 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4523) Limkain-b1 PF11608.8 KKF96311.1 - 0.034 14.2 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 DUF45 PF01863.17 KKF96311.1 - 0.055 13.5 0.1 0.078 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 PHM7_cyt PF14703.6 KKF96311.1 - 0.19 12.0 1.0 7.8 6.7 0.1 3.2 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter ATP-synt_D PF01813.17 KKF96312.1 - 1.4e-52 178.4 0.2 1.7e-52 178.2 0.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 KKF96312.1 - 0.025 14.1 0.1 0.035 13.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) CobA_CobO_BtuR PF02572.15 KKF96312.1 - 0.067 13.4 0.8 0.49 10.6 0.1 2.0 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP TPR_14 PF13428.6 KKF96313.1 - 1.3e-09 38.1 7.3 0.13 13.2 0.0 6.9 7 1 1 8 8 6 2 Tetratricopeptide repeat Suf PF05843.14 KKF96313.1 - 7.9e-08 32.6 3.7 0.0011 19.1 1.9 3.6 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KKF96313.1 - 4.6e-07 29.8 0.8 0.35 10.9 0.0 4.4 5 0 0 5 5 5 3 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 KKF96313.1 - 1.9e-06 27.3 0.7 0.00066 19.0 0.2 3.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKF96313.1 - 4.1e-06 26.6 1.6 1.4 9.3 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKF96313.1 - 0.00033 20.9 2.9 13 6.2 0.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKF96313.1 - 0.00079 19.9 0.0 11 6.6 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 KKF96313.1 - 0.0014 18.4 0.0 0.0036 17.0 0.0 1.8 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_17 PF13431.6 KKF96313.1 - 0.0039 17.5 2.7 1.2 9.7 0.1 4.7 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKF96313.1 - 0.006 16.6 8.0 2.9 8.2 0.0 5.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKF96313.1 - 0.066 13.9 0.2 5.3 7.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KKF96313.1 - 0.068 12.6 0.1 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 SHNi-TPR Pol_alpha_B_N PF08418.10 KKF96313.1 - 0.18 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal NSF PF02071.20 KKF96313.1 - 0.3 12.0 1.6 1.4e+02 4.0 0.0 5.0 6 0 0 6 6 4 0 Aromatic-di-Alanine (AdAR) repeat PolyA_pol PF01743.20 KKF96314.1 - 2.3e-26 92.7 0.1 4.1e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KKF96314.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Ribosomal_S17 PF00366.20 KKF96315.1 - 1.8e-21 76.0 2.0 1.8e-21 76.0 2.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 COG6 PF06419.11 KKF96316.1 - 1.7e-167 558.4 16.1 8e-136 453.8 8.8 3.0 1 1 2 3 3 3 3 Conserved oligomeric complex COG6 DUF1319 PF07028.11 KKF96316.1 - 0.47 10.7 3.6 1.3 9.3 1.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) APG9 PF04109.16 KKF96317.1 - 3.4e-113 379.2 0.6 4.1e-96 322.9 0.4 2.0 1 1 1 2 2 2 2 Autophagy protein Apg9 Mito_carr PF00153.27 KKF96318.1 - 9e-55 182.6 3.4 2.4e-21 75.4 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KKF96318.1 - 0.0056 15.9 2.0 0.19 10.9 0.2 2.3 1 1 1 2 2 2 2 Gammaproteobacterial serine protease DnaJ PF00226.31 KKF96319.1 - 2.4e-21 75.6 2.6 2.4e-20 72.4 1.3 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 KKF96319.1 - 5.4e-11 41.7 1.6 0.018 15.1 0.0 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKF96319.1 - 3.3e-10 39.3 0.0 0.0013 18.5 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKF96319.1 - 4.8e-09 36.2 3.6 0.00036 20.6 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKF96319.1 - 3.4e-08 33.6 3.3 0.47 11.4 0.0 5.3 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKF96319.1 - 7.2e-08 32.0 0.3 0.067 12.9 0.0 4.5 4 1 1 5 5 4 3 TPR repeat TPR_8 PF13181.6 KKF96319.1 - 1.4e-07 31.2 0.0 0.045 14.0 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKF96319.1 - 1.6e-06 28.7 3.2 0.72 10.6 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKF96319.1 - 1.8e-06 28.4 6.6 0.17 12.4 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKF96319.1 - 3.9e-05 23.7 0.1 0.0044 17.3 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat PknG_TPR PF16918.5 KKF96319.1 - 9.2e-05 21.3 1.4 0.0064 15.3 0.1 2.8 1 1 3 4 4 4 1 Protein kinase G tetratricopeptide repeat TPR_7 PF13176.6 KKF96319.1 - 0.0006 19.7 2.6 0.12 12.5 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF96319.1 - 0.0019 18.4 3.4 0.15 12.3 0.1 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KKF96319.1 - 0.0051 17.4 5.6 27 5.7 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKF96319.1 - 0.0054 17.0 3.4 0.36 11.2 0.1 4.4 3 2 2 5 5 5 1 Tetratricopeptide repeat RPT PF13446.6 KKF96319.1 - 0.12 12.3 0.1 1.5 8.8 0.0 2.9 3 1 0 3 3 3 0 A repeated domain in UCH-protein LBP_M PF17385.2 KKF96319.1 - 0.19 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain Cytochrom_B562 PF07361.11 KKF96319.1 - 0.22 12.2 9.5 2.9 8.6 0.1 4.7 3 1 1 4 4 4 0 Cytochrome b562 ArnB_C PF18677.1 KKF96319.1 - 0.9 9.7 5.0 20 5.4 0.1 3.6 4 0 0 4 4 3 0 Archaellum regulatory network B, C-terminal domain Ribosomal_L12 PF00542.19 KKF96319.1 - 5 7.5 6.3 1.4 9.3 1.7 2.4 2 1 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain KfrA_N PF11740.8 KKF96319.1 - 8.9 7.0 8.5 5.3 7.7 0.2 3.1 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Vac14_Fab1_bd PF12755.7 KKF96320.1 - 4.3e-34 117.0 0.1 6e-32 110.1 0.0 2.4 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KKF96320.1 - 2.9e-07 30.2 1.3 0.00041 20.4 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KKF96320.1 - 0.0003 21.2 0.1 0.047 14.2 0.0 3.5 3 0 0 3 3 3 1 HEAT-like repeat Tti2 PF10521.9 KKF96320.1 - 0.11 12.0 0.0 26 4.3 0.0 3.3 3 1 0 3 3 3 0 Tti2 family FA_desaturase PF00487.24 KKF96321.1 - 5.3e-26 92.0 25.8 9e-26 91.2 25.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KKF96321.1 - 1.3e-09 38.1 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.14 KKF96322.1 - 1.3e-65 221.6 2.7 1.7e-65 221.2 2.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKF96322.1 - 6.8e-42 142.2 0.0 1.8e-41 140.8 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KKF96322.1 - 3.4e-22 78.8 9.2 5.1e-19 68.6 0.5 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKF96322.1 - 6.3e-11 42.3 4.1 1e-06 28.9 0.5 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKF96322.1 - 5.4e-10 39.2 6.2 2.7e-09 36.9 0.2 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KKF96322.1 - 7.3e-09 35.2 7.0 1.1e-07 31.3 3.1 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KKF96322.1 - 1.7e-07 30.7 7.0 9.4e-07 28.2 2.8 2.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KKF96322.1 - 2.5e-06 26.5 10.9 0.00019 20.2 1.7 4.0 4 0 0 4 4 4 1 HI0933-like protein Thi4 PF01946.17 KKF96322.1 - 3.5e-06 26.5 2.3 0.00015 21.1 0.2 2.4 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 KKF96322.1 - 7.3e-06 25.4 2.4 0.023 14.0 0.2 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KKF96322.1 - 2.6e-05 23.5 0.1 0.24 10.5 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KKF96322.1 - 8.7e-05 21.9 6.1 0.013 14.7 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKF96322.1 - 0.00016 21.4 13.2 0.0056 16.3 1.4 3.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKF96322.1 - 0.00038 19.8 6.8 0.12 11.6 1.4 2.5 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KKF96322.1 - 0.015 14.3 4.2 0.033 13.2 0.5 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein THF_DHG_CYH_C PF02882.19 KKF96322.1 - 0.035 13.4 0.3 21 4.4 0.0 3.5 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KKF96322.1 - 0.046 14.2 0.5 11 6.6 0.1 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.19 KKF96322.1 - 0.17 10.3 0.5 0.28 9.5 0.5 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 KKF96322.1 - 0.3 9.9 5.2 0.041 12.7 0.7 1.8 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KKF96322.1 - 6.8 6.5 6.6 2.8 7.8 0.2 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MIF4G PF02854.19 KKF96323.1 - 6.3e-24 84.8 0.3 1.1e-23 84.0 0.3 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KKF96323.1 - 1.6e-06 28.0 0.0 5e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 MA3 domain DUF3089 PF11288.8 KKF96323.1 - 0.2 11.2 0.5 0.44 10.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) BUD22 PF09073.10 KKF96323.1 - 4 6.7 30.8 11 5.2 30.8 1.7 1 0 0 1 1 1 0 BUD22 SRP14 PF02290.15 KKF96324.1 - 2.4e-27 95.1 1.0 6.9e-27 93.7 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle 14kD protein RRM_1 PF00076.22 KKF96325.1 - 4.1e-45 151.4 0.0 9.2e-18 63.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KKF96325.1 - 1.7e-05 24.8 0.0 0.32 11.1 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 KKF96325.1 - 6.3e-05 23.0 0.1 5.2 7.2 0.0 3.8 3 1 0 3 3 3 3 Limkain b1 RRM_occluded PF16842.5 KKF96325.1 - 0.0027 17.5 0.0 5 7.1 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif ATP-grasp_2 PF08442.10 KKF96325.1 - 0.031 13.8 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain PknH_C PF14032.6 KKF96325.1 - 0.058 13.2 0.1 10 5.9 0.0 3.0 3 0 0 3 3 3 0 PknH-like extracellular domain RRM_5 PF13893.6 KKF96325.1 - 0.14 11.7 0.0 9.8 5.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COQ9 PF08511.11 KKF96326.1 - 3.5e-28 97.2 0.0 8.2e-28 96.0 0.0 1.6 2 0 0 2 2 2 1 COQ9 SMC_N PF02463.19 KKF96327.1 - 6.5e-10 38.8 0.4 6.5e-10 38.8 0.4 2.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain Sec34 PF04136.15 KKF96327.1 - 0.0022 17.9 6.9 0.0022 17.9 6.9 5.5 3 2 0 6 6 6 2 Sec34-like family Macoilin PF09726.9 KKF96327.1 - 0.0024 16.5 22.8 0.0024 16.5 22.8 3.0 2 1 1 3 3 3 1 Macoilin family Snapin_Pallidin PF14712.6 KKF96327.1 - 0.023 15.1 1.5 0.023 15.1 1.5 7.0 4 2 2 7 7 7 0 Snapin/Pallidin OPT PF03169.15 KKF96328.1 - 3.4e-162 541.3 57.3 3.8e-162 541.1 57.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2427 PF10348.9 KKF96328.1 - 1.3 8.8 10.6 0.13 12.1 2.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) SGT1 PF07093.11 KKF96329.1 - 4.3e-18 65.1 9.8 5.4e-12 44.9 0.0 2.3 2 0 0 2 2 2 2 SGT1 protein CDC45 PF02724.14 KKF96329.1 - 2.3 6.4 6.1 3.6 5.8 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein THUMP PF02926.17 KKF96331.1 - 9.7e-08 32.2 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 THUMP domain TPP_enzyme_N PF02776.18 KKF96332.1 - 2e-32 112.2 0.0 3.9e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKF96332.1 - 1.4e-22 79.9 0.0 5e-22 78.1 0.0 2.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKF96332.1 - 6.3e-12 45.5 0.1 3.9e-11 43.0 0.0 2.1 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DnaJ PF00226.31 KKF96333.1 - 4.2e-20 71.6 2.8 7.4e-20 70.8 2.8 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 KKF96333.1 - 0.017 15.5 1.3 0.026 14.8 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 KKF96333.1 - 0.017 15.2 3.7 0.028 14.5 3.7 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 KKF96333.1 - 7.5 6.4 10.9 16 5.3 11.0 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Glyco_hydro_18 PF00704.28 KKF96334.1 - 1.5e-78 264.7 9.3 2.2e-78 264.2 9.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.16 KKF96335.1 - 2.6e-07 29.9 35.8 0.00068 18.7 4.2 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily LRR_6 PF13516.6 KKF96336.1 - 8.6e-08 31.6 1.9 1.2 9.4 0.2 6.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 KKF96336.1 - 4.5e-06 26.9 10.5 0.49 10.9 0.5 5.8 6 1 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKF96336.1 - 0.0003 20.9 5.8 6.6 7.7 0.1 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 KKF96336.1 - 0.022 14.5 11.6 6.2 6.7 0.0 5.0 4 1 0 4 4 4 0 Leucine rich repeat Vpu PF00558.19 KKF96336.1 - 5.1 7.0 6.6 1.7 8.4 3.2 2.1 2 0 0 2 2 2 0 Vpu protein zf-H2C2_2 PF13465.6 KKF96337.1 - 4.6e-06 26.8 8.9 4.8e-06 26.7 1.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KKF96337.1 - 3.7e-05 24.0 0.3 3.7e-05 24.0 0.3 3.2 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KKF96337.1 - 5.9e-05 23.0 0.7 0.099 12.7 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KKF96337.1 - 0.001 19.7 4.3 0.018 15.9 0.3 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 KKF96337.1 - 0.0016 19.0 12.5 0.058 14.0 0.0 4.0 3 1 1 4 4 4 2 FOXP coiled-coil domain GCR1_C PF12550.8 KKF96337.1 - 0.28 11.5 2.1 0.24 11.7 0.5 1.8 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes DUF3090 PF11290.8 KKF96337.1 - 3.6 7.4 9.6 0.17 11.7 1.4 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3090) Sina PF03145.16 KKF96337.1 - 7.7 6.4 10.8 17 5.3 2.6 2.9 1 1 1 2 2 2 0 Seven in absentia protein family Fe_hyd_lg_C PF02906.14 KKF96338.1 - 3.3e-52 177.6 0.0 5.7e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SUZ PF12752.7 KKF96339.1 - 0.00037 21.2 12.1 0.00037 21.2 12.1 4.4 1 1 1 2 2 2 1 SUZ domain ATP_sub_h PF10775.9 KKF96341.1 - 6.3e-24 83.8 0.8 1e-23 83.0 0.8 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h Pkinase PF00069.25 KKF96342.1 - 1e-67 228.3 0.0 1.3e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96342.1 - 1e-30 106.9 0.0 1.4e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KKF96342.1 - 3.5e-13 50.0 0.1 9.9e-13 48.6 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KKF96342.1 - 6.1e-09 35.6 0.0 2.2e-08 33.8 0.0 1.8 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 KKF96342.1 - 1.1e-05 25.7 0.1 0.0001 22.5 0.1 2.2 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 KKF96342.1 - 0.00027 20.0 0.1 0.00063 18.8 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKF96342.1 - 0.0072 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_E3_15_3 PF03307.14 KKF96342.1 - 0.034 14.1 0.0 0.092 12.7 0.0 1.7 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region APH PF01636.23 KKF96342.1 - 0.039 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KKF96342.1 - 0.052 13.2 0.1 3.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SWI-SNF_Ssr4 PF08549.10 KKF96343.1 - 1e-167 560.0 8.0 1.8e-108 364.2 0.0 3.8 1 1 2 3 3 3 3 Fungal domain of unknown function (DUF1750) 6PGD PF00393.19 KKF96344.1 - 1.2e-126 422.0 0.0 1.5e-126 421.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKF96344.1 - 6e-51 172.7 0.0 9.2e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KKF96344.1 - 0.024 15.2 0.0 0.051 14.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RRM_1 PF00076.22 KKF96345.1 - 1.8e-16 59.7 0.0 4e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytotoxic PF09000.10 KKF96345.1 - 0.036 14.4 0.1 0.036 14.4 0.1 2.4 2 0 0 2 2 2 0 Cytotoxic OB_RNB PF08206.11 KKF96345.1 - 0.19 11.4 0.2 0.39 10.4 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain TPT PF03151.16 KKF96346.1 - 1.1e-18 67.6 17.1 1.5e-18 67.2 17.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KKF96346.1 - 7.1e-06 26.2 39.4 0.00058 20.0 18.7 2.6 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KKF96346.1 - 0.91 8.7 20.6 2.1 7.5 20.6 1.7 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport UAA PF08449.11 KKF96346.1 - 1 8.5 24.8 0.36 10.0 21.4 1.9 2 1 0 2 2 2 0 UAA transporter family G-patch PF01585.23 KKF96347.1 - 2.8e-05 23.9 0.0 0.00013 21.8 0.0 2.3 1 1 0 1 1 1 1 G-patch domain DUF936 PF06075.12 KKF96347.1 - 1.6 7.5 38.3 2.3 7.0 38.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) rRNA_processing PF08524.11 KKF96347.1 - 2.2 8.3 44.8 1 9.4 16.4 2.5 2 0 0 2 2 2 0 rRNA processing Zn_clus PF00172.18 KKF96348.1 - 8e-05 22.7 7.9 0.00018 21.6 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKF96348.1 - 0.044 12.8 0.0 0.13 11.3 0.0 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain EPL1 PF10513.9 KKF96348.1 - 2.8 8.3 11.2 0.24 11.8 3.3 2.8 2 0 0 2 2 2 0 Enhancer of polycomb-like GvpL_GvpF PF06386.11 KKF96348.1 - 3.8 7.4 8.8 2 8.3 3.5 2.4 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Spt20 PF12090.8 KKF96348.1 - 7.5 6.1 26.4 3.5 7.2 0.4 2.8 3 0 0 3 3 3 0 Spt20 family RhoGAP PF00620.27 KKF96349.1 - 1.5e-42 145.0 0.0 2.5e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KKF96349.1 - 4.4e-13 49.6 0.0 1e-12 48.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KKF96349.1 - 2.2e-05 24.8 1.2 3.5e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KKF96349.1 - 0.014 15.6 0.1 0.066 13.5 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain CFIA_Pcf11 PF11526.8 KKF96349.1 - 9.2 6.8 7.2 1.9 9.0 2.7 2.2 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Rhodanese PF00581.20 KKF96350.1 - 8.6e-12 45.5 0.0 1.8e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Iwr1 PF08574.10 KKF96350.1 - 0.72 10.9 6.0 3.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Transcription factor Iwr1 Zn_clus PF00172.18 KKF96351.1 - 0.05 13.7 4.6 0.095 12.8 4.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MRP-S26 PF14943.6 KKF96351.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Aminotran_3 PF00202.21 KKF96352.1 - 1.3e-110 369.9 0.0 1.5e-110 369.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KKF96352.1 - 0.037 13.2 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aldedh PF00171.22 KKF96353.1 - 1.8e-162 541.1 0.1 2e-162 540.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PRA1 PF03208.19 KKF96354.1 - 1.8e-37 128.2 0.3 2.3e-37 127.8 0.3 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF572 PF04502.13 KKF96355.1 - 0.11 12.1 16.3 0.16 11.6 16.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) YqjK PF13997.6 KKF96356.1 - 0.48 10.7 3.7 8.7 6.7 0.7 2.3 1 1 1 2 2 2 0 YqjK-like protein CPSase_L_D2 PF02786.17 KKF96357.1 - 1.2e-80 269.9 0.8 1.9e-80 269.3 0.8 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KKF96357.1 - 3.8e-70 235.7 0.0 6.8e-70 234.9 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_C PF02785.19 KKF96357.1 - 7.7e-32 109.6 0.0 2.2e-31 108.2 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KKF96357.1 - 3.2e-27 95.7 0.0 6.7e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_carb_N PF00289.22 KKF96357.1 - 1.1e-21 77.4 0.1 2.6e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KKF96357.1 - 6.5e-18 64.3 4.9 7.3e-18 64.2 2.7 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KKF96357.1 - 1.3e-10 41.2 0.0 2.6e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KKF96357.1 - 7e-10 38.6 0.2 5.7e-06 26.1 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 KKF96357.1 - 2.6e-08 33.6 0.1 5.2e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KKF96357.1 - 3.1e-05 24.1 0.0 7.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KKF96357.1 - 3.3e-05 23.6 0.0 0.00013 21.6 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KKF96357.1 - 0.00018 21.1 0.1 0.00052 19.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 KKF96357.1 - 0.003 16.8 0.2 0.053 12.7 0.1 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 KKF96357.1 - 0.032 13.5 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 KKF96357.1 - 0.037 14.0 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.6 KKF96357.1 - 0.037 14.7 0.1 6.7 7.5 0.0 3.4 3 1 1 4 4 2 0 HlyD family secretion protein NQRA PF05896.11 KKF96357.1 - 0.085 12.3 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATPgrasp_Ter PF15632.6 KKF96357.1 - 0.12 12.2 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_YheCD PF14398.6 KKF96357.1 - 0.16 11.2 0.0 5.2 6.2 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp GCV_H PF01597.19 KKF96357.1 - 0.4 10.6 2.3 1.1 9.2 0.1 2.7 2 1 1 3 3 3 0 Glycine cleavage H-protein Mog1 PF04603.12 KKF96358.1 - 3.4e-32 111.7 0.0 8.2e-32 110.5 0.0 1.6 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Glucan_synthase PF02364.15 KKF96359.1 - 0 1375.5 0.0 0 1374.9 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KKF96359.1 - 5.6e-43 146.4 0.7 1.8e-42 144.8 0.7 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aconitase PF00330.20 KKF96360.1 - 1.7e-147 492.2 0.0 2.2e-147 491.8 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKF96360.1 - 5.2e-44 149.7 0.0 8.8e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain PCI PF01399.27 KKF96361.1 - 2.6e-09 37.5 0.0 6e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KKF96361.1 - 1.8e-07 30.6 3.8 4.2e-07 29.4 3.8 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix NmrA PF05368.13 KKF96362.1 - 8.2e-06 25.5 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKF96362.1 - 8.9e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKF96362.1 - 1.3e-05 24.7 0.0 3.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKF96362.1 - 1.8e-05 23.9 0.0 3.4e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family N6-adenineMlase PF10237.9 KKF96363.1 - 5.1e-53 179.1 0.1 6.4e-53 178.8 0.1 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase F_actin_bund_C PF18060.1 KKF96363.1 - 0.057 13.5 3.7 0.088 12.9 3.7 1.2 1 0 0 1 1 1 0 F actin bundling C terminal Rsa3 PF14615.6 KKF96364.1 - 1.4e-18 66.1 0.2 1.7e-18 65.9 0.2 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DUF5112 PF17139.4 KKF96364.1 - 0.0028 17.2 0.1 0.003 17.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5112) Hpt PF01627.23 KKF96364.1 - 0.029 14.6 0.5 0.037 14.3 0.5 1.1 1 0 0 1 1 1 0 Hpt domain CBS PF00571.28 KKF96365.1 - 9.8e-10 38.7 0.4 1.3e-05 25.5 0.0 3.7 3 1 0 3 3 3 2 CBS domain Importin_rep_4 PF18808.1 KKF96366.1 - 2.5e-32 111.0 1.9 2.5e-32 111.0 1.9 4.6 6 1 1 7 7 5 1 Importin repeat Importin_rep_5 PF18816.1 KKF96366.1 - 5.1e-19 68.3 0.3 4e-18 65.4 0.2 2.5 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 KKF96366.1 - 4e-18 65.5 20.5 1e-09 38.7 0.5 9.8 9 2 2 11 11 10 4 HEAT-like repeat HEAT PF02985.22 KKF96366.1 - 1.5e-17 62.2 17.0 0.0059 16.8 0.0 11.4 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 KKF96366.1 - 9.3e-15 54.8 16.2 2.8e-07 30.8 0.1 8.6 6 2 3 9 9 8 3 HEAT repeats Importin_rep_6 PF18829.1 KKF96366.1 - 1.9e-13 50.5 4.5 6.8e-13 48.7 0.4 3.7 4 0 0 4 4 4 1 Importin repeat 6 RIX1 PF08167.12 KKF96366.1 - 1.5e-11 44.4 0.3 3.2e-05 23.8 0.0 5.9 5 1 0 5 5 4 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 KKF96366.1 - 5.3e-10 39.8 0.1 0.018 15.6 0.0 7.0 4 1 3 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KKF96366.1 - 8.3e-08 32.4 0.1 0.94 9.5 0.0 5.4 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KKF96366.1 - 6.9e-07 29.3 0.4 1.9 8.4 0.0 7.1 4 2 1 7 7 7 1 Domain of unknown function (DUF3385) DRIM PF07539.12 KKF96366.1 - 2.2e-06 26.3 3.7 0.0037 15.6 0.0 4.2 3 2 1 5 5 5 2 Down-regulated in metastasis CLASP_N PF12348.8 KKF96366.1 - 0.00037 20.1 0.0 4 6.9 0.0 5.1 5 1 0 6 6 6 1 CLASP N terminal MMS19_C PF12460.8 KKF96366.1 - 0.00075 18.7 3.1 0.011 14.9 0.0 3.9 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 KKF96366.1 - 0.002 16.8 1.1 0.061 11.9 0.2 3.4 3 1 1 4 4 4 1 Adaptin N terminal region TFCD_C PF12612.8 KKF96366.1 - 0.0054 16.6 0.1 0.92 9.3 0.0 4.0 3 1 1 4 4 4 1 Tubulin folding cofactor D C terminal CobN-Mg_chel PF02514.16 KKF96366.1 - 0.012 13.4 0.0 0.017 12.9 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Cohesin_HEAT PF12765.7 KKF96366.1 - 0.013 15.7 0.0 70 3.9 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion IBN_N PF03810.19 KKF96366.1 - 0.014 15.2 0.0 1.1 9.2 0.0 3.4 2 1 0 2 2 2 0 Importin-beta N-terminal domain Xpo1 PF08389.12 KKF96366.1 - 0.025 14.6 0.1 0.32 11.1 0.0 3.0 3 0 0 3 3 3 0 Exportin 1-like protein MMS19_N PF14500.6 KKF96366.1 - 0.066 12.8 0.9 20 4.7 0.0 3.8 6 0 0 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II Phage_term_smal PF05944.12 KKF96366.1 - 0.088 12.8 0.3 2.5 8.1 0.0 3.4 3 1 1 4 4 3 0 Phage small terminase subunit Arm PF00514.23 KKF96366.1 - 0.11 12.5 8.6 0.52 10.4 0.0 5.4 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat Telomere_reg-2 PF10193.9 KKF96366.1 - 0.59 10.6 8.2 0.24 11.8 0.5 3.8 4 1 0 4 4 3 0 Telomere length regulation protein Glyco_tranf_2_3 PF13641.6 KKF96367.1 - 6.1e-21 75.4 0.0 1e-20 74.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KKF96367.1 - 9.4e-18 64.8 0.5 9.4e-18 64.8 0.5 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KKF96367.1 - 2e-14 53.8 0.0 3.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KKF96367.1 - 7.4e-13 48.3 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 KKF96367.1 - 1e-12 47.4 4.9 5.2e-09 35.2 5.1 2.3 1 1 1 2 2 2 2 Cellulose synthase Chitin_synth_2 PF03142.15 KKF96367.1 - 0.022 13.4 0.4 0.15 10.6 0.2 2.1 2 0 0 2 2 2 0 Chitin synthase Glyco_hydro_12 PF01670.16 KKF96368.1 - 3.1e-19 69.8 4.0 5.9e-18 65.6 4.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 ISN1 PF06437.11 KKF96369.1 - 1.2e-188 627.1 0.0 1.4e-188 627.0 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Pkinase PF00069.25 KKF96370.1 - 2e-55 188.0 0.0 2.9e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96370.1 - 1.3e-27 96.7 0.6 3.7e-26 92.0 0.2 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF96370.1 - 8.2e-05 22.1 0.2 0.041 13.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 KKF96370.1 - 0.0049 16.5 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KKF96370.1 - 0.015 14.1 0.0 0.028 13.2 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KKF96370.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tox-GHH PF15636.6 KKF96371.1 - 0.22 11.5 5.3 0.69 9.9 5.3 1.8 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin MMM1 PF10296.9 KKF96372.1 - 3e-05 23.2 0.2 0.0028 16.8 0.0 2.3 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Autophagy_N PF03986.13 KKF96373.1 - 1.1e-45 155.0 0.4 2.7e-45 153.7 0.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KKF96373.1 - 5.1e-16 57.9 0.6 1e-15 56.9 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KKF96373.1 - 1.3e-15 57.7 0.1 2.6e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain S4 PF01479.25 KKF96374.1 - 2.3e-12 46.4 0.9 2.3e-12 46.4 0.9 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KKF96374.1 - 5.8e-06 27.1 0.4 1e-05 26.3 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 KKF96374.1 - 0.08 13.1 0.6 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Ribosomal_L21e PF01157.18 KKF96375.1 - 7.9e-47 157.3 2.9 1.3e-46 156.6 2.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e DUF5486 PF17588.2 KKF96375.1 - 0.017 15.0 1.3 0.063 13.2 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Slu7 PF11708.8 KKF96376.1 - 3.7e-69 233.5 12.1 3.7e-69 233.5 12.1 2.6 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KKF96376.1 - 0.024 14.3 0.6 0.045 13.5 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle HGD-D PF06050.13 KKF96376.1 - 0.049 13.4 0.6 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component Pkinase PF00069.25 KKF96377.1 - 1.7e-20 73.5 0.0 2.8e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96377.1 - 6.2e-15 55.2 0.0 9.7e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Lactonase PF10282.9 KKF96377.1 - 0.049 12.9 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DNA_pol_B PF00136.21 KKF96380.1 - 4.3e-95 319.1 0.0 7e-95 318.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KKF96380.1 - 2.9e-17 62.8 0.0 5.6e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KKF96380.1 - 0.013 15.9 0.1 0.034 14.6 0.1 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KKF96380.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Mcp5_PH PF12814.7 KKF96381.1 - 2.8e-36 124.3 0.6 4.9e-36 123.5 0.0 1.8 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology HAP1_N PF04849.13 KKF96381.1 - 0.00017 20.9 7.0 0.00017 20.9 7.0 4.7 3 1 1 4 4 4 3 HAP1 N-terminal conserved region Cnn_1N PF07989.11 KKF96381.1 - 0.0058 16.8 5.2 0.0058 16.8 5.2 4.5 4 0 0 4 4 4 1 Centrosomin N-terminal motif 1 PH_2 PF08458.10 KKF96381.1 - 0.029 14.7 0.0 0.08 13.3 0.0 1.7 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH PF00169.29 KKF96381.1 - 0.14 12.6 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 PH domain Ribosomal_L18A PF01775.17 KKF96382.1 - 2.4e-54 182.6 0.3 3.2e-54 182.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Peptidase_M2 PF01401.18 KKF96382.1 - 0.088 11.4 0.0 0.098 11.3 0.0 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme PGAP1 PF07819.13 KKF96383.1 - 3.7e-90 301.7 0.0 5.2e-90 301.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KKF96383.1 - 0.00012 22.8 0.1 0.00034 21.3 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKF96383.1 - 0.0035 16.7 0.0 0.0076 15.5 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KKF96383.1 - 0.0054 16.4 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 KKF96383.1 - 0.017 15.0 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_1 PF00561.20 KKF96383.1 - 0.029 14.0 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.14 KKF96383.1 - 0.03 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KKF96383.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 KKF96383.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 KKF96384.1 - 7e-18 64.7 28.2 3.3e-17 62.5 25.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KKF96384.1 - 1.9e-12 47.2 4.0 1.9e-12 47.2 4.0 2.1 2 1 0 2 2 2 1 Nodulin-like Serinc PF03348.15 KKF96385.1 - 2.5e-158 527.5 12.5 2.8e-158 527.4 12.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) FB_lectin PF07367.11 KKF96385.1 - 0.22 11.4 0.6 0.4 10.6 0.1 1.6 2 0 0 2 2 2 0 Fungal fruit body lectin MSP1_C PF07462.11 KKF96385.1 - 1.1 7.9 1.5 1.5 7.4 1.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Cys_Met_Meta_PP PF01053.20 KKF96386.1 - 3.1e-137 457.2 0.1 3.6e-137 457.0 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KKF96386.1 - 3.7e-06 26.2 0.3 7.8e-06 25.1 0.2 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKF96386.1 - 4.1e-06 26.2 0.0 6.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KKF96386.1 - 0.00027 19.6 0.2 0.00059 18.5 0.2 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 KKF96386.1 - 0.00056 19.3 0.2 0.0023 17.3 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 KKF96386.1 - 0.0048 15.8 0.1 0.0071 15.2 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein AAA PF00004.29 KKF96387.1 - 9e-38 129.7 0.0 1.6e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKF96387.1 - 6.4e-08 32.3 0.1 1.9e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 KKF96387.1 - 1.1e-06 28.7 0.0 3.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKF96387.1 - 1.2e-06 29.0 0.6 2.9e-05 24.5 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KKF96387.1 - 3.6e-06 27.2 0.0 9.6e-06 25.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKF96387.1 - 6.7e-06 25.9 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKF96387.1 - 9.9e-06 25.6 0.2 0.00011 22.3 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKF96387.1 - 7.2e-05 23.3 0.0 0.0009 19.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain TniB PF05621.11 KKF96387.1 - 8.8e-05 22.0 0.0 0.17 11.3 0.0 2.4 1 1 0 2 2 2 2 Bacterial TniB protein AAA_22 PF13401.6 KKF96387.1 - 9.1e-05 22.7 1.3 0.0044 17.3 0.0 2.5 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.6 KKF96387.1 - 0.00023 21.3 0.1 0.00055 20.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 KKF96387.1 - 0.00043 20.2 0.3 0.0021 18.0 0.1 2.3 2 1 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 KKF96387.1 - 0.00076 19.8 0.0 0.0023 18.3 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 KKF96387.1 - 0.00097 18.6 0.1 0.002 17.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KKF96387.1 - 0.0014 18.3 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KKF96387.1 - 0.0036 16.9 1.3 0.05 13.2 0.1 2.6 2 1 1 3 3 3 1 AAA domain NACHT PF05729.12 KKF96387.1 - 0.0044 16.9 0.1 0.016 15.1 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 KKF96387.1 - 0.0055 17.0 0.1 0.014 15.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KKF96387.1 - 0.0094 15.7 0.0 0.021 14.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KKF96387.1 - 0.0094 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.13 KKF96387.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KKF96387.1 - 0.012 16.1 0.1 0.05 14.1 0.0 2.1 3 0 0 3 3 1 0 ABC transporter Sigma54_activat PF00158.26 KKF96387.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 KKF96387.1 - 0.022 15.2 0.2 0.11 12.9 0.1 2.2 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KKF96387.1 - 0.031 14.2 0.1 0.14 12.1 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 KKF96387.1 - 0.036 13.3 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 KKF96387.1 - 0.045 13.3 0.0 0.087 12.3 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KKF96387.1 - 0.046 13.7 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Guanylate_kin PF00625.21 KKF96387.1 - 0.048 13.4 0.0 0.71 9.5 0.0 2.8 2 1 1 3 3 3 0 Guanylate kinase Oxidored_nitro PF00148.19 KKF96387.1 - 0.058 12.1 0.0 3 6.5 0.0 2.2 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Parvo_NS1 PF01057.17 KKF96387.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KKF96387.1 - 0.064 12.4 0.0 0.7 9.0 0.0 2.3 2 1 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 KKF96387.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 KKF96387.1 - 0.085 12.1 1.4 0.09 12.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 KKF96387.1 - 0.092 12.1 0.0 0.5 9.7 0.0 2.1 1 1 1 2 2 2 0 KaiC SKI PF01202.22 KKF96387.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 Shikimate kinase IPT PF01745.16 KKF96387.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_3 PF07726.11 KKF96387.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_trans_NIPA PF05653.14 KKF96388.1 - 3.3e-101 338.3 19.3 4.1e-101 338.0 19.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KKF96388.1 - 8.2e-06 26.0 8.4 8.2e-06 26.0 8.4 3.6 3 1 0 3 3 3 1 EamA-like transporter family NOA36 PF06524.12 KKF96388.1 - 1.3 8.3 3.1 2.1 7.6 3.1 1.3 1 0 0 1 1 1 0 NOA36 protein Acyl_transf_3 PF01757.22 KKF96388.1 - 3.9 6.4 21.8 36 3.3 16.9 2.1 1 1 1 2 2 2 0 Acyltransferase family Ribosomal_S3_C PF00189.20 KKF96389.1 - 3.4e-25 88.4 0.2 1.8e-24 86.0 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KKF96389.1 - 5.3e-12 45.4 0.1 1.2e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KKF96389.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KKF96389.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Coilin N-terminus Myotub-related PF06602.14 KKF96390.1 - 1.1e-117 392.9 0.0 1.1e-114 383.0 0.0 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KKF96390.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase tRNA_synthFbeta PF17759.1 KKF96391.1 - 6.1e-47 159.8 0.0 9.1e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KKF96391.1 - 9e-30 102.7 0.6 6.9e-29 99.9 0.0 2.6 3 1 1 4 4 4 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KKF96391.1 - 6.8e-24 84.5 0.0 1.3e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KKF96391.1 - 1.4e-17 63.7 0.0 3.4e-15 56.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.22 KKF96392.1 - 1.2e-36 121.6 21.8 0.0053 16.9 0.1 13.4 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 KKF96392.1 - 8.2e-34 115.9 2.1 2.7e-10 40.5 0.0 8.1 3 3 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.7 KKF96392.1 - 6.9e-13 49.0 1.1 0.12 12.9 0.1 6.7 4 1 5 9 9 9 5 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KKF96392.1 - 7.9e-11 42.2 11.9 0.026 15.1 0.0 8.6 9 1 1 10 10 10 2 HEAT-like repeat Cnd1 PF12717.7 KKF96392.1 - 6.6e-08 32.8 13.3 0.0016 18.5 0.2 5.8 3 2 4 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KKF96392.1 - 2.7e-06 26.2 11.1 0.0071 15.0 4.4 5.1 3 1 1 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 KKF96392.1 - 9.7e-05 22.5 4.9 4.8 7.4 0.0 5.1 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 RPA_interact_N PF14766.6 KKF96392.1 - 0.16 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Replication protein A interacting N-terminal M11L PF11099.8 KKF96392.1 - 0.29 11.4 1.4 22 5.3 0.0 3.5 2 1 1 3 3 3 0 Apoptosis regulator M11L like Proteasom_PSMB PF10508.9 KKF96392.1 - 1.3 7.5 5.6 4.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Methyltransf_31 PF13847.6 KKF96393.1 - 1.1e-13 51.3 0.0 1.1e-13 51.3 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF96393.1 - 0.00014 22.5 3.7 0.00016 22.3 0.1 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF96393.1 - 0.00051 20.7 0.0 0.00051 20.7 0.0 3.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF96393.1 - 0.0014 19.2 0.0 0.008 16.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KKF96393.1 - 0.0099 16.2 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 KKF96393.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW bMG10 PF17973.1 KKF96393.1 - 3.9 7.7 6.7 5 7.3 3.0 3.1 3 0 0 3 3 3 0 Bacterial Alpha-2-macroglobulin MG10 domain ABC_membrane PF00664.23 KKF96396.1 - 4.9e-92 308.5 31.8 1.3e-50 172.6 13.5 2.8 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKF96396.1 - 3.3e-48 163.7 0.0 1e-28 100.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKF96396.1 - 2.8e-10 40.0 2.8 0.0068 15.9 0.3 4.3 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KKF96396.1 - 6.9e-06 26.1 1.7 0.16 12.0 0.4 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKF96396.1 - 0.00018 21.5 0.1 0.36 10.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KKF96396.1 - 0.00046 20.6 1.6 0.044 14.2 0.7 2.5 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 KKF96396.1 - 0.00098 19.2 5.0 0.1 12.7 0.0 3.4 3 0 0 3 3 3 1 Dynamin family AAA_21 PF13304.6 KKF96396.1 - 0.0033 17.3 0.2 1.1 9.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKF96396.1 - 0.0042 16.8 1.9 2.8 7.8 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF87 PF01935.17 KKF96396.1 - 0.0066 16.6 0.6 0.74 9.9 0.2 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KKF96396.1 - 0.0086 15.8 1.0 2.9 7.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain MWFE PF15879.5 KKF96396.1 - 0.013 15.7 0.5 0.11 12.7 0.1 2.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit RNA_helicase PF00910.22 KKF96396.1 - 0.034 14.5 0.0 7.2 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KKF96396.1 - 0.041 13.2 0.1 6.3 6.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KKF96396.1 - 0.081 12.6 0.1 2.4 7.8 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.6 KKF96396.1 - 0.26 11.8 3.0 9.8 6.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KKF96396.1 - 0.27 11.5 1.0 56 4.0 0.1 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KKF96396.1 - 0.54 10.5 3.4 39 4.5 0.1 3.5 3 1 0 3 3 2 0 AAA domain ABC_membrane_2 PF06472.15 KKF96396.1 - 1.2 8.5 10.6 0.14 11.6 0.2 2.6 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 AAA_15 PF13175.6 KKF96396.1 - 1.3 8.7 6.2 3.8 7.1 0.0 3.0 4 0 0 4 4 4 0 AAA ATPase domain efThoc1 PF11957.8 KKF96397.1 - 2.3e-109 366.3 0.1 2.6e-66 224.3 0.2 2.1 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 KKF96397.1 - 2e-14 53.7 0.1 7.6e-13 48.5 0.0 2.5 1 1 1 2 2 2 2 Guanylate kinase Aquarius_N PF16399.5 KKF96398.1 - 0 1039.0 0.0 0 1038.7 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KKF96398.1 - 6.8e-26 91.1 0.0 1.2e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKF96398.1 - 2.7e-19 70.0 0.0 6.4e-19 68.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF96398.1 - 9.3e-07 29.3 0.1 2.9e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKF96398.1 - 5.4e-06 26.2 0.0 0.0012 18.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KKF96398.1 - 2.7e-05 24.2 0.0 8.1e-05 22.7 0.0 1.8 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KKF96398.1 - 0.00092 18.8 0.0 0.0032 17.0 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KKF96398.1 - 0.0021 17.8 0.4 1.5 8.5 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 KKF96398.1 - 0.004 16.5 0.0 0.037 13.3 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KKF96398.1 - 0.0077 16.6 0.0 0.032 14.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KKF96398.1 - 0.016 15.6 0.0 0.055 13.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KKF96398.1 - 0.021 14.7 0.4 0.021 14.7 0.4 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Adeno_IVa2 PF02456.15 KKF96398.1 - 0.026 13.4 0.1 0.046 12.5 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_22 PF13401.6 KKF96398.1 - 0.036 14.4 0.6 0.37 11.1 0.2 2.6 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 KKF96398.1 - 0.091 12.8 0.0 7 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KKF96398.1 - 0.096 12.1 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF2075 PF09848.9 KKF96398.1 - 0.16 11.2 0.0 0.37 10.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MIF4G PF02854.19 KKF96399.1 - 3.8e-45 154.1 0.0 7.4e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KKF96399.1 - 2e-20 72.7 0.4 2e-20 72.7 0.4 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 4G1 DNA_pol_B PF00136.21 KKF96400.1 - 3e-112 375.7 0.1 4.6e-112 375.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KKF96400.1 - 1.5e-54 184.6 0.7 2.7e-54 183.7 0.7 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KKF96400.1 - 1.8e-42 145.7 0.0 2.8e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KKF96400.1 - 2.2e-21 75.7 6.9 2.2e-21 75.7 6.9 2.4 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KKF96400.1 - 0.023 13.6 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral ThiG PF05690.14 KKF96400.1 - 0.19 11.0 0.1 0.36 10.1 0.1 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PPR_2 PF13041.6 KKF96401.1 - 0.12 12.6 0.1 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 PPR repeat family ATP-synt_B PF00430.18 KKF96401.1 - 5.5 7.1 9.3 22 5.1 9.3 2.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) LON_substr_bdg PF02190.16 KKF96402.1 - 6.5e-21 75.2 0.0 2e-20 73.6 0.0 1.8 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KKF96402.1 - 3e-10 39.8 8.8 5.8e-10 38.8 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKF96402.1 - 1.3e-05 25.0 5.8 2.9e-05 23.8 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKF96402.1 - 1.7e-05 24.6 7.3 3.1e-05 23.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKF96402.1 - 1.7e-05 24.7 10.7 3.6e-05 23.7 10.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KKF96402.1 - 5.3e-05 23.5 7.9 0.00014 22.2 7.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KKF96402.1 - 0.00021 21.2 6.3 0.00048 20.0 6.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KKF96402.1 - 0.00035 20.6 7.8 0.00077 19.6 7.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KKF96402.1 - 0.008 16.0 6.8 0.018 14.9 6.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KKF96402.1 - 0.065 13.0 0.6 0.2 11.5 0.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KKF96402.1 - 1.3 9.2 4.8 2.4 8.3 4.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Chalcone_2 PF16035.5 KKF96403.1 - 3.8e-68 229.3 0.0 4.7e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone PF02431.15 KKF96403.1 - 0.016 14.6 0.0 0.22 10.9 0.0 2.4 2 1 0 3 3 3 0 Chalcone-flavanone isomerase Chalcone_3 PF16036.5 KKF96403.1 - 0.024 14.7 0.0 0.072 13.2 0.0 1.7 2 0 0 2 2 2 0 Chalcone isomerase-like Glutaredoxin PF00462.24 KKF96404.1 - 0.00013 22.1 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin UQ_con PF00179.26 KKF96405.1 - 0.0061 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_L13 PF00572.18 KKF96406.1 - 1.6e-11 44.5 0.0 1.4e-09 38.3 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 BAG PF02179.16 KKF96407.1 - 1.1e-16 60.9 0.2 2e-16 60.2 0.2 1.4 1 0 0 1 1 1 1 BAG domain Ribosomal_S10 PF00338.22 KKF96408.1 - 9.2e-27 93.2 0.2 1.1e-26 92.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Bestrophin PF01062.21 KKF96409.1 - 4.2e-32 111.7 0.2 1.4e-31 110.0 0.2 1.7 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel CLP_protease PF00574.23 KKF96410.1 - 5.4e-69 231.7 0.1 8.8e-69 231.0 0.1 1.3 1 0 0 1 1 1 1 Clp protease RRG8 PF17068.5 KKF96411.1 - 0.04 13.3 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial DUF655 PF04919.12 KKF96412.1 - 0.061 13.3 2.8 0.1 12.6 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF655) PspB PF06667.12 KKF96412.1 - 0.33 11.0 2.2 3.9 7.6 0.4 3.1 2 0 0 2 2 2 0 Phage shock protein B DUF4407 PF14362.6 KKF96412.1 - 1.5 8.1 22.6 0.08 12.3 9.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3287 PF11690.8 KKF96412.1 - 5.5 6.7 5.9 1 9.1 0.9 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) Flagellar_rod PF05149.12 KKF96412.1 - 7.1 6.0 17.3 7.6 5.9 15.3 1.9 1 1 1 2 2 2 0 Paraflagellar rod protein Methyltransf_25 PF13649.6 KKF96414.1 - 6.5e-16 58.8 0.0 1.2e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF96414.1 - 2e-10 41.2 0.0 4.1e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF96414.1 - 4.4e-09 36.3 0.0 7.6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF96414.1 - 5.7e-09 36.6 0.0 1.1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF96414.1 - 8.2e-09 35.5 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKF96414.1 - 3.8e-06 26.4 0.0 5.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 KKF96414.1 - 0.00021 20.9 0.0 0.14 11.6 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain PCMT PF01135.19 KKF96414.1 - 0.0056 16.5 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KKF96414.1 - 0.0056 17.7 0.0 0.016 16.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CTV_P33 PF07184.11 KKF96414.1 - 0.024 13.7 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein MTS PF05175.14 KKF96414.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain NAS PF03059.16 KKF96414.1 - 0.087 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein Methyltransf_32 PF13679.6 KKF96414.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Exo_endo_phos PF03372.23 KKF96415.1 - 4.3e-22 78.8 0.9 1.2e-20 74.1 0.2 2.7 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KKF96415.1 - 6.6e-11 41.8 6.7 9.5e-08 31.7 1.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KKF96415.1 - 6.1e-09 36.0 2.6 0.0025 18.2 0.7 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) YL1 PF05764.13 KKF96418.1 - 3.7e-64 217.2 33.3 3.7e-64 217.2 33.3 2.8 4 0 0 4 4 4 1 YL1 nuclear protein YL1_C PF08265.11 KKF96418.1 - 3.1e-15 55.6 0.4 5.5e-15 54.8 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF2849 PF11011.8 KKF96418.1 - 0.0072 17.0 0.1 0.0072 17.0 0.1 4.2 3 2 1 4 4 4 1 Protein of unknown function (DUF2849) Med10 PF09748.9 KKF96419.1 - 2.6e-44 150.1 0.0 3.1e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KKF96419.1 - 0.0098 15.8 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) TPR_1 PF00515.28 KKF96420.1 - 1.3e-38 129.3 10.5 1.4e-07 31.0 0.2 8.5 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 KKF96420.1 - 2.2e-38 127.3 6.5 1.8e-06 27.6 0.1 8.3 8 1 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.31 KKF96420.1 - 1.9e-27 95.2 2.6 5.5e-27 93.7 2.6 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 KKF96420.1 - 2e-25 88.2 15.4 8.2e-09 35.0 0.7 7.2 6 2 2 8 8 7 5 TPR repeat TPR_19 PF14559.6 KKF96420.1 - 1.5e-21 76.7 5.9 5.9e-05 23.5 0.0 6.4 4 3 3 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KKF96420.1 - 9.4e-21 72.2 5.0 5.5e-05 23.1 0.2 7.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KKF96420.1 - 3.8e-20 72.2 0.0 1e-06 29.3 0.0 5.9 5 2 1 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KKF96420.1 - 1.2e-18 67.1 5.6 0.022 15.0 0.0 7.1 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KKF96420.1 - 2.3e-18 65.2 7.1 0.056 13.8 0.0 7.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKF96420.1 - 8.9e-16 57.2 5.1 0.0014 19.2 0.1 8.5 4 3 6 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKF96420.1 - 8.8e-14 50.4 4.6 0.076 13.1 0.1 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF96420.1 - 2.2e-13 50.2 1.1 0.006 16.8 0.2 3.9 3 2 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KKF96420.1 - 7e-12 45.3 0.3 0.0033 17.5 0.1 4.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KKF96420.1 - 3.3e-09 36.3 6.4 0.22 11.5 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKF96420.1 - 3.7e-09 36.6 6.1 0.038 14.6 0.4 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 KKF96420.1 - 1.4e-07 31.0 1.4 0.069 12.4 0.0 4.3 3 1 0 4 4 4 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KKF96420.1 - 0.00083 19.8 1.0 2.7 8.5 0.1 3.8 2 1 2 4 4 4 1 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 KKF96420.1 - 0.0011 18.9 4.1 2.2 8.4 0.1 5.1 5 2 2 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KKF96420.1 - 0.0015 18.8 1.7 2.2 8.7 0.0 4.6 4 2 1 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 KKF96420.1 - 0.0018 18.3 7.0 2.6 8.2 0.1 4.8 3 2 1 4 4 4 1 MIT (microtubule interacting and transport) domain BTAD PF03704.17 KKF96420.1 - 0.0027 18.2 5.5 2.3 8.6 0.1 4.7 3 2 3 6 6 6 1 Bacterial transcriptional activator domain NARP1 PF12569.8 KKF96420.1 - 0.0037 16.2 0.8 0.12 11.3 0.2 3.0 3 1 0 3 3 3 1 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 KKF96420.1 - 0.017 15.2 0.2 18 5.4 0.0 4.6 5 1 0 5 5 5 0 Domain of Unknown Function (DUF3856) Coatomer_E PF04733.14 KKF96420.1 - 0.02 14.3 0.2 0.46 9.8 0.0 2.8 3 0 0 3 3 3 0 Coatomer epsilon subunit SRP_TPR_like PF17004.5 KKF96420.1 - 0.082 12.9 1.0 1.9 8.6 0.0 3.0 2 1 1 3 3 3 0 Putative TPR-like repeat TPR_MalT PF17874.1 KKF96420.1 - 0.11 11.8 0.3 0.89 8.9 0.1 2.5 1 1 1 2 2 2 0 MalT-like TPR region TPR_4 PF07721.14 KKF96420.1 - 2.5 9.0 10.2 9.6 7.2 0.0 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat EF-hand_6 PF13405.6 KKF96421.1 - 3e-13 48.5 0.7 4.5e-06 26.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KKF96421.1 - 4.5e-11 41.5 2.7 0.00015 21.1 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KKF96421.1 - 3e-10 40.4 4.2 3.6e-07 30.5 1.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KKF96421.1 - 9.7e-07 28.0 5.3 0.002 17.6 0.5 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KKF96421.1 - 2.2e-05 24.2 0.9 0.029 14.2 0.2 3.0 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 KKF96421.1 - 0.00098 19.4 0.0 1.4 9.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPA PF08616.10 KKF96422.1 - 2.2e-37 127.5 0.0 4.1e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 KKF96422.1 - 1.7e-35 122.4 2.8 1.7e-35 122.4 2.8 1.7 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 KKF96422.1 - 2.8e-06 26.3 0.2 0.16 10.6 0.0 4.3 3 1 2 5 5 5 2 Transport protein Avl9 DUF2347 PF09804.9 KKF96422.1 - 0.0074 15.9 0.0 0.061 12.9 0.0 2.4 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2347) DUF1168 PF06658.12 KKF96422.1 - 3.7 7.4 9.3 0.26 11.1 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Nop14 PF04147.12 KKF96422.1 - 5 5.2 11.8 2.8 6.1 8.0 1.9 2 0 0 2 2 2 0 Nop14-like family Esterase PF00756.20 KKF96423.1 - 9.3e-46 156.5 0.9 3.1e-44 151.5 0.9 2.0 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KKF96423.1 - 0.00054 19.5 0.1 0.0023 17.5 0.1 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KKF96423.1 - 0.00093 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KKF96423.1 - 0.0019 17.1 0.1 0.0034 16.3 0.1 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KKF96423.1 - 0.0026 17.1 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KKF96423.1 - 0.16 11.0 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase PGAP1 PF07819.13 KKF96423.1 - 0.19 11.4 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein RNA_pol_Rpb6 PF01192.22 KKF96424.1 - 5.2e-17 61.5 0.4 2.4e-16 59.4 0.1 2.0 1 1 1 2 2 2 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 KKF96425.1 - 1.9e-27 94.1 61.3 2.4e-05 24.5 0.5 9.6 9 1 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKF96425.1 - 3.6e-16 58.5 59.5 0.0041 17.8 0.3 9.7 10 0 0 10 10 9 7 C2H2-type zinc finger FOXP-CC PF16159.5 KKF96425.1 - 4.9e-13 49.5 23.7 0.00043 20.9 0.2 7.8 3 1 5 8 8 8 3 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KKF96425.1 - 5.6e-11 42.3 55.4 3.3e-05 24.1 0.2 9.6 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KKF96425.1 - 0.0003 21.0 21.2 6 7.3 0.0 8.0 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KKF96425.1 - 0.0054 16.9 24.9 0.32 11.1 2.4 5.0 1 1 6 7 7 7 4 Aberrant zinc-finger zf-H2C2_5 PF13909.6 KKF96425.1 - 0.015 15.1 5.3 0.015 15.1 5.3 8.9 10 0 0 10 10 10 0 C2H2-type zinc-finger domain IBD PF10416.9 KKF96425.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD zf-met PF12874.7 KKF96425.1 - 0.14 12.6 27.1 1.9 9.0 0.2 8.0 9 0 0 9 9 8 0 Zinc-finger of C2H2 type zf_Hakai PF18408.1 KKF96425.1 - 0.22 11.3 0.0 0.22 11.3 0.0 6.0 6 1 1 7 7 7 0 C2H2 Hakai zinc finger domain zf-C2H2_3rep PF18868.1 KKF96425.1 - 0.44 11.2 16.8 2.2 8.9 2.8 4.6 3 1 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 KKF96425.1 - 0.86 9.9 22.3 2.2 8.6 6.7 4.4 2 1 1 4 4 4 0 C2H2-type zinc ribbon OrsD PF12013.8 KKF96425.1 - 2.2 8.8 28.1 5.2 7.5 0.1 6.4 4 2 1 6 6 6 0 Orsellinic acid/F9775 biosynthesis cluster protein D Endonuclease_NS PF01223.23 KKF96426.1 - 4e-63 213.3 0.0 4.8e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease UPF0258 PF06789.12 KKF96426.1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) WD40 PF00400.32 KKF96427.1 - 3.7e-31 106.7 21.3 5.2e-05 23.9 1.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF96427.1 - 1.8e-12 47.4 0.1 0.41 11.0 0.0 6.0 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKF96427.1 - 0.09 12.7 0.0 10 5.9 0.0 2.7 1 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.19 KKF96428.1 - 5.7e-20 72.0 13.6 7.5e-20 71.6 13.6 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KKF96428.1 - 0.003 17.8 3.0 0.0092 16.2 3.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ICMT PF04140.14 KKF96429.1 - 3.9e-23 81.7 1.7 4.7e-23 81.4 0.6 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KKF96429.1 - 3e-14 53.3 1.1 7e-14 52.1 1.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KKF96429.1 - 1.2e-05 25.0 1.2 1.7e-05 24.4 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KKF96429.1 - 0.0015 18.1 5.6 0.0015 18.1 5.6 1.9 2 0 0 2 2 2 1 NnrU protein DUF3561 PF12084.8 KKF96429.1 - 5.1 7.2 10.9 0.42 10.7 2.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3561) Mac PF12464.8 KKF96430.1 - 1e-10 41.7 0.3 1.4e-10 41.2 0.3 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase ATG11 PF10377.9 KKF96431.1 - 0.025 14.6 0.1 0.51 10.4 0.0 2.5 2 1 0 2 2 2 0 Autophagy-related protein 11 DUF1775 PF07987.11 KKF96431.1 - 0.059 13.6 0.3 5.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unkown function (DUF1775) adh_short PF00106.25 KKF96432.1 - 5.9e-86 286.9 14.2 1.7e-44 151.6 2.1 2.8 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKF96432.1 - 4.8e-68 229.2 6.3 3.6e-35 121.6 0.2 2.6 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KKF96432.1 - 1.1e-34 118.6 0.0 2.1e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KKF96432.1 - 3.3e-31 108.6 5.5 1.1e-15 58.0 0.3 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 KKF96432.1 - 6e-06 26.4 0.0 0.028 14.6 0.0 2.5 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 KKF96432.1 - 4.4e-05 22.8 0.8 0.00062 19.1 0.4 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KKF96432.1 - 0.076 12.5 5.8 0.31 10.4 0.2 2.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Glucodextran_B PF09136.10 KKF96432.1 - 0.3 11.5 3.5 0.22 11.9 0.3 2.4 2 0 0 2 2 2 0 Glucodextranase, domain B 3HCDH_N PF02737.18 KKF96432.1 - 0.38 10.6 4.4 3.2 7.6 0.6 2.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAM25 PF15825.5 KKF96432.1 - 0.65 10.4 8.5 3.1 8.2 1.0 3.3 3 0 0 3 3 3 0 FAM25 family AAA_16 PF13191.6 KKF96433.1 - 0.00053 20.4 0.0 0.00061 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain PRK PF00485.18 KKF96433.1 - 0.0031 17.3 0.0 0.0038 17.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KKF96433.1 - 0.004 17.1 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.22 KKF96433.1 - 0.0054 16.4 0.0 0.007 16.0 0.0 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KKF96433.1 - 0.0078 16.8 0.0 0.01 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKF96433.1 - 0.014 15.9 0.0 0.018 15.4 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KKF96433.1 - 0.026 13.8 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.22 KKF96433.1 - 0.035 14.5 0.0 0.065 13.6 0.0 1.4 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KKF96433.1 - 0.035 14.0 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 KKF96433.1 - 0.038 14.0 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KKF96433.1 - 0.074 13.3 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KKF96433.1 - 0.085 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 KKF96433.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KKF96433.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KKF96433.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_29 PF13555.6 KKF96433.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KKF96433.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 KKF96433.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ECM11 PF15463.6 KKF96434.1 - 1.1e-44 152.2 1.1 3.4e-44 150.7 1.1 1.8 1 0 0 1 1 1 1 Extracellular mutant protein 11 Xpo1 PF08389.12 KKF96435.1 - 3e-24 85.8 1.0 3e-24 85.8 1.0 3.1 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KKF96435.1 - 4.9e-10 39.2 1.6 6.9e-10 38.7 0.2 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 KKF96435.1 - 0.0049 15.5 1.0 0.12 11.0 0.3 2.5 2 0 0 2 2 2 1 Adaptin N terminal region DUF1002 PF06207.11 KKF96435.1 - 0.022 14.3 0.1 0.064 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) HEAT_EZ PF13513.6 KKF96435.1 - 0.061 13.9 1.1 12 6.5 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat Death PF00531.22 KKF96435.1 - 0.12 12.6 0.8 1.1 9.5 0.2 2.7 2 0 0 2 2 2 0 Death domain Cullin PF00888.22 KKF96435.1 - 0.16 10.6 0.0 0.3 9.7 0.0 1.4 1 0 0 1 1 1 0 Cullin family LSM PF01423.22 KKF96436.1 - 2.4e-17 62.3 0.2 2.9e-17 62.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KKF96436.1 - 5.5e-05 22.7 0.2 7.8e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 Hfq protein 5-FTHF_cyc-lig PF01812.20 KKF96437.1 - 1.5e-26 93.4 0.0 1.8e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family OPT PF03169.15 KKF96438.1 - 2e-55 188.6 11.4 2.2e-55 188.5 11.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MAD PF05557.13 KKF96439.1 - 1.3e-55 189.1 58.0 1.3e-55 189.1 58.0 3.1 2 1 0 2 2 2 1 Mitotic checkpoint protein muHD PF10291.9 KKF96439.1 - 6.4e-47 160.2 0.0 1.6e-46 158.9 0.0 1.7 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KKF96439.1 - 7.7e-10 38.9 2.0 1.6e-09 37.9 0.1 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4094 PF13334.6 KKF96439.1 - 0.015 15.7 0.2 0.015 15.7 0.2 6.0 6 2 0 6 6 6 0 Domain of unknown function (DUF4094) Adap_comp_sub PF00928.21 KKF96439.1 - 0.1 12.0 0.0 0.28 10.5 0.0 1.7 1 0 0 1 1 1 0 Adaptor complexes medium subunit family Sec20 PF03908.13 KKF96439.1 - 9.5 6.2 10.5 19 5.3 0.4 4.1 3 0 0 3 3 3 0 Sec20 Pkinase PF00069.25 KKF96440.1 - 4.9e-31 108.1 0.0 6.8e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96440.1 - 8.2e-11 41.7 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKF96440.1 - 0.00084 19.3 0.0 0.032 14.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKF96440.1 - 0.0037 16.6 0.0 0.0091 15.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKF96440.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KKF96440.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TGFb_propeptide PF00688.18 KKF96441.1 - 0.1 12.3 0.2 0.14 11.9 0.2 1.4 1 1 0 1 1 1 0 TGF-beta propeptide DHBP_synthase PF00926.19 KKF96442.1 - 6.7e-78 260.6 0.1 7.9e-78 260.4 0.1 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.6 KKF96443.1 - 8e-11 42.0 0.0 9.9e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF96443.1 - 1.6e-08 35.1 0.0 2.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF96443.1 - 7.9e-06 25.7 0.0 8.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF96443.1 - 1.2e-05 26.0 0.0 1.8e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF96443.1 - 0.00097 19.8 0.0 0.0014 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ANAPC4 PF12896.7 KKF96444.1 - 1.7e-44 151.8 0.0 3.3e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KKF96444.1 - 1.1e-12 48.0 0.0 3.1e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Gtr1_RagA PF04670.12 KKF96445.1 - 5.4e-66 222.3 0.1 7.1e-66 221.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Tim17 PF02466.19 KKF96446.1 - 3.9e-32 110.9 7.0 4.9e-32 110.6 7.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3617 PF12276.8 KKF96446.1 - 0.00034 20.9 0.3 0.00064 20.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3617) FSH1 PF03959.13 KKF96446.1 - 0.039 13.6 0.2 0.044 13.4 0.2 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AMPK1_CBM PF16561.5 KKF96447.1 - 2.8e-25 88.3 0.0 5.2e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KKF96447.1 - 2.7e-21 75.6 0.3 1.2e-20 73.5 0.3 2.2 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain Peptidase_M22 PF00814.25 KKF96448.1 - 2.3e-75 253.8 0.0 2.8e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KKF96448.1 - 0.0068 16.1 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus Hamartin PF04388.12 KKF96449.1 - 3.2 6.3 18.0 4.8 5.7 18.0 1.3 1 0 0 1 1 1 0 Hamartin protein EF-hand_1 PF00036.32 KKF96450.1 - 3.2e-26 88.9 13.7 3.1e-07 29.4 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KKF96450.1 - 1.2e-22 80.2 14.4 1.2e-13 51.3 1.9 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KKF96450.1 - 1.8e-19 68.0 8.7 8.3e-05 22.2 0.4 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KKF96450.1 - 5.5e-18 63.6 12.0 1e-06 28.0 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KKF96450.1 - 3.8e-11 42.7 13.2 0.00015 21.5 0.4 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KKF96450.1 - 5.6e-06 26.6 0.0 0.013 15.8 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KKF96450.1 - 8.9e-05 22.4 8.3 0.053 13.5 0.3 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KKF96450.1 - 0.0087 16.2 0.9 0.038 14.2 0.8 2.2 1 1 0 1 1 1 1 Dockerin type I domain EF-hand_9 PF14658.6 KKF96450.1 - 0.098 13.0 0.2 3.3 8.1 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain Ribosomal_S9 PF00380.19 KKF96452.1 - 1.5e-40 138.5 0.6 2.7e-40 137.7 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein S9/S16 Fis1_TPR_C PF14853.6 KKF96452.1 - 0.037 14.1 0.2 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF3168 PF11367.8 KKF96452.1 - 0.084 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) EF1G PF00647.19 KKF96453.1 - 3.9e-42 142.7 0.4 6.4e-42 142.0 0.4 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KKF96453.1 - 1.4e-15 57.2 0.1 3.3e-15 56.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKF96453.1 - 1.5e-12 47.7 0.0 4.6e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKF96453.1 - 2.7e-06 27.7 0.0 6.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKF96453.1 - 2.2e-05 24.4 0.4 9.9e-05 22.3 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKF96453.1 - 0.00093 19.5 0.0 0.0026 18.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KKF96453.1 - 0.0014 18.8 0.3 0.0046 17.1 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 KKF96453.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RRP36 PF06102.12 KKF96454.1 - 1.1e-53 181.6 28.7 1.9e-53 180.8 25.8 2.1 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Es2 PF09751.9 KKF96455.1 - 8.6e-102 342.1 3.6 1.3e-101 341.5 3.6 1.3 1 0 0 1 1 1 1 Nuclear protein Es2 ABC1 PF03109.16 KKF96455.1 - 1.6e-32 112.1 0.0 2.7e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family PT-VENN PF04829.13 KKF96455.1 - 0.029 14.4 0.6 0.082 13.0 0.6 1.7 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif PPP5 PF08321.12 KKF96456.1 - 4.4e-32 110.2 0.3 8.7e-32 109.3 0.3 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 KKF96456.1 - 5.8e-31 108.6 0.1 8.6e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KKF96456.1 - 1e-14 53.6 1.1 1.8e-06 27.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKF96456.1 - 2.2e-11 42.9 0.8 3.2e-05 23.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKF96456.1 - 5.9e-08 32.3 0.5 0.059 13.1 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 KKF96456.1 - 0.00013 22.0 0.0 0.097 12.8 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKF96456.1 - 0.00015 21.7 0.1 0.16 12.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKF96456.1 - 0.015 15.6 0.8 0.68 10.4 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKF96456.1 - 0.046 14.4 0.7 4.7 7.9 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKF96456.1 - 0.13 13.2 0.2 2.9 9.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKF96456.1 - 0.14 12.8 0.0 1 10.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Spt4 PF06093.13 KKF96457.1 - 3e-31 107.3 0.2 3.7e-31 107.1 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger BH3 PF15285.6 KKF96457.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Kin17_mid PF10357.9 KKF96458.1 - 3.7e-52 175.5 2.3 3.7e-52 175.5 2.3 2.1 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KKF96458.1 - 5.7e-07 29.7 0.3 1.8e-06 28.1 0.3 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKF96458.1 - 0.00083 19.7 0.6 0.002 18.4 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKF96458.1 - 0.7 10.3 7.7 0.13 12.7 1.2 2.6 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Pox_A11 PF05061.13 KKF96458.1 - 0.92 8.7 3.4 1.6 7.9 3.1 1.4 1 1 0 1 1 1 0 Poxvirus A11 Protein DUF572 PF04502.13 KKF96459.1 - 6.3e-64 216.7 6.9 7.4e-64 216.5 6.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 KKF96459.1 - 0.0063 16.6 1.6 0.64 10.2 0.1 2.4 2 0 0 2 2 2 2 Acetyl-coA carboxylase zinc finger domain DUF951 PF06107.11 KKF96459.1 - 0.17 11.8 0.4 25 4.9 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) Flu_NS1 PF00600.19 KKF96459.1 - 0.2 11.2 2.1 0.31 10.5 2.1 1.2 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) GREB1 PF15782.5 KKF96459.1 - 2.3 5.2 5.6 2.8 5.0 5.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer USP7_ICP0_bdg PF12436.8 KKF96460.1 - 1.1e-75 254.1 0.0 2.5e-74 249.6 0.0 2.5 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KKF96460.1 - 3.4e-52 177.1 2.3 1.3e-48 165.5 1.2 3.7 3 1 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KKF96460.1 - 3.7e-40 138.1 0.0 4.6e-30 105.0 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKF96460.1 - 6.9e-20 71.9 0.2 1.4e-11 44.6 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KKF96460.1 - 4.4e-09 36.5 0.0 1.4e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 MATH domain Malt_amylase_C PF16657.5 KKF96460.1 - 0.02 15.0 0.1 1.3 9.2 0.0 2.8 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain ParD PF09386.10 KKF96460.1 - 0.063 13.7 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 Antitoxin ParD Homeodomain PF00046.29 KKF96460.1 - 0.36 10.7 1.7 18 5.3 0.4 3.0 2 0 0 2 2 2 0 Homeodomain BCDHK_Adom3 PF10436.9 KKF96461.1 - 2e-34 118.8 0.1 3.4e-34 118.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KKF96461.1 - 1.7e-07 31.7 0.0 4.1e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KKF96461.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Septin PF00735.18 KKF96462.1 - 1.6e-114 381.9 0.3 2.5e-114 381.3 0.3 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KKF96462.1 - 1.5e-07 31.5 0.0 3.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKF96462.1 - 6.2e-06 26.2 1.6 3.2e-05 23.9 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KKF96462.1 - 1.3e-05 24.9 4.4 8e-05 22.3 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KKF96462.1 - 0.0022 18.3 0.7 0.0067 16.7 0.1 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KKF96462.1 - 0.0029 17.1 0.1 0.006 16.1 0.1 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 KKF96462.1 - 0.0039 17.4 0.1 0.009 16.2 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KKF96462.1 - 0.0071 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KKF96462.1 - 0.009 15.1 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FOXP-CC PF16159.5 KKF96462.1 - 0.01 16.4 0.8 0.01 16.4 0.8 2.3 2 1 0 2 2 1 0 FOXP coiled-coil domain AAA_24 PF13479.6 KKF96462.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Casc1_N PF15927.5 KKF96462.1 - 0.018 14.8 10.9 0.045 13.4 10.9 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ras PF00071.22 KKF96462.1 - 0.019 14.5 0.4 0.066 12.8 0.5 1.9 2 1 0 2 2 1 0 Ras family AAA_25 PF13481.6 KKF96462.1 - 0.025 14.2 0.4 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKF96462.1 - 0.031 14.7 1.6 0.065 13.6 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KKF96462.1 - 0.037 14.5 0.3 0.18 12.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.14 KKF96462.1 - 0.039 13.2 0.0 0.05 12.8 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 KKF96462.1 - 0.044 12.8 0.6 0.15 11.1 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 KKF96462.1 - 0.046 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 KKF96462.1 - 0.068 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KKF96462.1 - 0.11 12.9 0.0 0.35 11.3 0.0 1.9 2 0 0 2 2 1 0 RNA helicase PduV-EutP PF10662.9 KKF96462.1 - 0.11 12.2 0.4 4.7 6.9 0.4 2.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KKF96462.1 - 0.44 10.6 6.3 5.2 7.1 0.0 3.1 2 1 1 3 3 3 0 Dynamin family Adaptin_binding PF10199.9 KKF96462.1 - 0.77 10.4 7.5 1.1 9.8 7.5 1.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Ribosomal_L6e PF01159.19 KKF96462.1 - 1.2 9.7 6.5 8.1 7.0 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e FUSC PF04632.12 KKF96462.1 - 3.7 6.0 4.5 5.3 5.4 4.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_11 PF13086.6 KKF96462.1 - 5.3 6.7 7.2 17 5.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain DegS PF05384.11 KKF96462.1 - 8.9 5.8 14.5 1.6 8.2 7.5 2.8 2 1 1 3 3 3 0 Sensor protein DegS WD40 PF00400.32 KKF96463.1 - 2.4e-44 148.4 30.1 2.7e-08 34.3 0.2 13.4 14 0 0 14 14 13 8 WD domain, G-beta repeat Utp12 PF04003.12 KKF96463.1 - 1.4e-23 83.3 0.0 2.1e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KKF96463.1 - 2.2e-21 75.9 0.0 0.00032 20.9 0.0 9.9 3 2 7 11 11 11 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKF96463.1 - 1.4e-08 34.9 0.3 0.13 12.1 0.2 5.1 4 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KKF96463.1 - 4e-08 32.6 1.2 0.8 8.6 0.0 6.2 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KKF96463.1 - 4.1e-06 25.7 3.1 0.11 11.1 0.0 4.2 3 2 2 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KKF96463.1 - 0.00016 21.1 0.0 0.21 10.8 0.0 3.7 4 0 0 4 4 4 1 WD40-like domain Nbas_N PF15492.6 KKF96463.1 - 0.0007 19.0 0.1 7.8 5.7 0.0 4.1 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal RPN1_RPN2_N PF17781.1 KKF96463.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain PALB2_WD40 PF16756.5 KKF96463.1 - 0.066 12.1 0.0 3.1 6.6 0.0 2.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Utp13 PF08625.11 KKF96463.1 - 0.17 11.8 0.2 0.39 10.6 0.2 1.6 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain NAP PF00956.18 KKF96464.1 - 1.8e-28 99.5 3.7 6.3e-28 97.7 3.7 1.8 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Cytomega_UL84 PF06284.11 KKF96464.1 - 0.39 9.1 1.5 0.52 8.7 1.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CENP-B_dimeris PF09026.10 KKF96464.1 - 4.1 7.9 10.0 0.45 10.9 3.7 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.19 KKF96464.1 - 6.3 7.5 19.6 0.11 13.1 6.5 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Pkinase PF00069.25 KKF96465.1 - 9.9e-62 208.7 0.0 1.2e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96465.1 - 2.4e-27 95.9 0.0 3.4e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKF96465.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KKF96465.1 - 0.046 13.0 0.0 0.3 10.3 0.0 2.4 3 1 0 3 3 3 0 Kinase-like DUF3915 PF13054.6 KKF96465.1 - 0.84 9.6 2.3 1.6 8.7 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) GGACT PF06094.12 KKF96466.1 - 5.6e-08 33.4 0.2 1.1e-06 29.3 0.2 2.1 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Glyco_hydro_61 PF03443.14 KKF96467.1 - 0.0037 17.2 0.1 0.008 16.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Methyltransf_32 PF13679.6 KKF96468.1 - 4.1e-22 78.9 1.2 2.2e-21 76.5 1.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain Type2_restr_D3 PF16902.5 KKF96468.1 - 0.015 15.2 1.1 0.059 13.3 1.1 2.0 1 1 0 1 1 1 0 Type-2 restriction enzyme D3 domain DUF5301 PF17225.3 KKF96469.1 - 0.008 16.6 5.6 0.015 15.7 2.5 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF5300) Abhydrolase_1 PF00561.20 KKF96470.1 - 1.5e-05 24.8 0.1 0.0012 18.5 0.1 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Pkinase PF00069.25 KKF96471.1 - 9.2e-37 126.8 0.0 1.9e-31 109.4 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96471.1 - 6.3e-19 68.3 0.0 2e-18 66.6 0.0 1.5 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF96471.1 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KKF96471.1 - 0.023 14.6 0.1 0.085 12.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKF96471.1 - 0.069 12.1 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KKF96471.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LptE PF04390.12 KKF96471.1 - 0.2 12.3 4.5 0.45 11.2 3.5 2.1 2 0 0 2 2 2 0 Lipopolysaccharide-assembly zf-RanBP PF00641.18 KKF96472.1 - 2.3e-18 65.2 11.8 6.3e-11 41.4 1.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KKF96472.1 - 7e-08 32.2 0.0 1.8e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KKF96472.1 - 3.5e-05 24.4 0.0 5.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease F-box PF00646.33 KKF96473.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF2457 PF10446.9 KKF96473.1 - 3.7 6.6 13.4 5.9 5.9 13.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 KKF96473.1 - 8.9 6.0 10.1 18 4.9 10.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAF1C_H4-bd PF12265.8 KKF96474.1 - 5.8e-27 93.8 1.9 1.6e-26 92.3 0.5 2.4 2 1 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KKF96474.1 - 6.8e-23 80.5 9.8 1.3e-06 29.1 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF96474.1 - 4.6e-05 23.6 2.1 0.00083 19.6 0.3 3.2 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KKF96474.1 - 0.032 12.3 0.0 0.05 11.6 0.0 1.3 1 0 0 1 1 1 0 IKI3 family SGL PF08450.12 KKF96474.1 - 0.047 13.3 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region XRN_M PF17846.1 KKF96475.1 - 3.7e-98 329.4 4.0 3.7e-98 329.4 4.0 2.2 2 0 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KKF96475.1 - 2.4e-97 325.2 0.3 4.9e-97 324.1 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KKF96475.1 - 4.5e-67 225.5 0.0 7.7e-67 224.8 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KKF96475.1 - 1.3e-30 105.4 0.0 3.7e-30 104.0 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KKF96475.1 - 6.4e-17 61.4 0.1 1.9e-16 59.9 0.1 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain SPC22 PF04573.12 KKF96476.1 - 6.3e-38 129.9 0.1 4.4e-37 127.2 0.1 1.9 1 1 0 1 1 1 1 Signal peptidase subunit Ras PF00071.22 KKF96477.1 - 4.2e-41 140.3 0.0 7.2e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF96477.1 - 2.4e-29 102.0 0.0 5e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Mannosidase_ig PF17786.1 KKF96477.1 - 2.2e-12 47.4 0.0 6.7e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Arf PF00025.21 KKF96477.1 - 1.5e-10 40.8 0.0 5.8e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKF96477.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKF96477.1 - 0.021 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_30 PF13604.6 KKF96477.1 - 0.048 13.4 0.1 9.3 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKF96477.1 - 0.053 13.9 0.0 0.36 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KKF96477.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KKF96477.1 - 0.057 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KKF96477.1 - 0.057 13.3 0.0 0.55 10.1 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KKF96477.1 - 0.11 12.8 0.1 0.32 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KKF96477.1 - 0.12 12.1 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CactinC_cactus PF09732.9 KKF96478.1 - 2.3e-58 195.5 4.8 3.9e-58 194.8 4.8 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 KKF96478.1 - 2.8e-55 187.1 2.2 4.1e-55 186.6 2.2 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin adh_short PF00106.25 KKF96478.1 - 3.1e-32 111.6 0.8 1.5e-21 76.8 0.2 2.5 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKF96478.1 - 4.4e-25 88.6 1.8 4.7e-17 62.3 0.5 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF96478.1 - 0.00015 21.7 0.1 0.62 10.0 0.0 2.6 2 0 0 2 2 2 2 KR domain HI0933_like PF03486.14 KKF96478.1 - 0.014 14.2 0.2 0.028 13.1 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein SF3A2 PF16835.5 KKF96478.1 - 0.024 15.0 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) CPSF100_C PF13299.6 KKF96479.1 - 0.51 10.5 3.8 0.61 10.2 3.8 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 KKF96479.1 - 0.52 10.6 5.9 0.56 10.5 5.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CobT PF06213.12 KKF96479.1 - 1 8.7 17.2 1.1 8.6 17.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SGT1 PF07093.11 KKF96479.1 - 1.2 7.5 14.6 1.2 7.5 14.6 1.0 1 0 0 1 1 1 0 SGT1 protein DUF2428 PF10350.9 KKF96479.1 - 1.9 7.6 4.2 2.2 7.5 4.2 1.0 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) DUF2457 PF10446.9 KKF96479.1 - 2.5 7.1 31.5 2.7 7.0 31.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 KKF96479.1 - 3.4 7.5 22.5 3.9 7.3 22.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 KKF96479.1 - 3.6 5.8 19.9 3.7 5.7 19.9 1.0 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 KKF96479.1 - 3.9 7.2 11.2 4.2 7.1 11.2 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RPN2_C PF18004.1 KKF96479.1 - 4.8 7.1 7.4 5.3 6.9 7.4 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC27 PF09507.10 KKF96479.1 - 4.9 6.4 11.5 5 6.4 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 KKF96479.1 - 6.6 4.8 27.1 6.2 4.9 27.1 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KKF96479.1 - 7.8 5.8 25.6 8 5.8 25.6 1.0 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 KKF96479.1 - 8.1 6.2 15.1 11 5.8 15.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Forkhead PF00250.18 KKF96480.1 - 3.5e-21 75.3 0.3 1.3e-20 73.5 0.1 2.0 1 1 1 2 2 2 1 Forkhead domain Prenyltrans PF00432.21 KKF96483.1 - 3.6e-16 58.6 11.6 2.3e-06 27.2 0.1 4.3 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Innate_immun PF12782.7 KKF96484.1 - 0.0014 18.2 2.1 0.0017 17.9 2.1 1.1 1 0 0 1 1 1 1 Invertebrate innate immunity transcript family DND1_DSRM PF14709.7 KKF96484.1 - 0.02 15.2 0.1 0.043 14.1 0.1 1.7 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KKF96484.1 - 0.14 12.9 0.2 0.47 11.2 0.0 2.1 2 1 0 2 2 2 0 Double-stranded RNA binding motif SelP_N PF04592.14 KKF96484.1 - 0.48 9.8 6.5 0.64 9.4 6.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NTP_transferase PF00483.23 KKF96485.1 - 2.8e-54 184.3 0.0 6.4e-54 183.1 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KKF96485.1 - 1.4e-17 62.7 11.9 1.4e-10 40.5 1.6 3.9 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KKF96485.1 - 1.3e-11 45.1 0.0 1.8e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KKF96485.1 - 1.4e-05 24.7 9.3 0.00011 21.9 1.5 3.4 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KKF96485.1 - 3.4e-05 22.2 0.1 9.2e-05 20.8 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) IspD PF01128.19 KKF96485.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 KKF96485.1 - 0.21 11.5 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase DUF4129 PF13559.6 KKF96486.1 - 0.0037 17.5 0.0 0.0067 16.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 KKF96486.1 - 0.049 13.6 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 NICE-3 protein Ndc1_Nup PF09531.10 KKF96487.1 - 6.4e-169 563.5 6.6 7.7e-169 563.3 6.6 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Methyltransf_3 PF01596.17 KKF96487.1 - 1e-09 37.9 0.0 1.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KKF96487.1 - 2e-08 35.2 0.0 5.9e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Syntaxin_2 PF14523.6 KKF96488.1 - 3.9e-20 72.1 6.5 3.9e-20 72.1 6.5 2.7 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KKF96488.1 - 2.1e-14 53.3 0.6 5.7e-14 51.8 0.6 1.8 1 0 0 1 1 1 1 SNARE domain ODV-E18 PF10717.9 KKF96488.1 - 0.0069 16.2 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 Synaptobrevin PF00957.21 KKF96488.1 - 0.0074 16.1 4.7 0.0084 15.9 2.4 2.3 2 0 0 2 2 2 1 Synaptobrevin Syntaxin PF00804.25 KKF96488.1 - 0.025 14.3 14.5 0.058 13.1 14.5 1.7 1 1 0 1 1 1 0 Syntaxin K_channel_TID PF07941.11 KKF96488.1 - 0.033 14.6 0.3 0.033 14.6 0.3 2.1 3 0 0 3 3 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF883 PF05957.13 KKF96488.1 - 0.14 12.8 11.6 0.24 12.0 0.7 3.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Nre_C PF04895.12 KKF96488.1 - 0.31 11.0 2.3 1.4 8.9 0.5 2.5 2 0 0 2 2 2 0 Archaeal Nre, C-terminal DUF2207 PF09972.9 KKF96488.1 - 0.73 8.5 4.3 0.5 9.1 0.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MCPsignal PF00015.21 KKF96488.1 - 1.8 8.3 13.4 23 4.7 10.3 2.8 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 KKF96488.1 - 5 7.2 9.7 3.1 7.8 2.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ALG11_N PF15924.5 KKF96489.1 - 2.4e-27 96.4 0.0 3.6e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KKF96489.1 - 2e-19 69.8 0.0 2.7e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKF96489.1 - 1.3e-11 45.0 0.1 3.4e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 G_glu_transpept PF01019.21 KKF96490.1 - 2.1e-167 558.0 0.0 2.4e-167 557.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Pyridoxal_deC PF00282.19 KKF96491.1 - 9.4e-20 70.7 0.0 1.8e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KKF96491.1 - 0.0076 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKF96491.1 - 0.021 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Antimicrobial_8 PF08103.11 KKF96491.1 - 0.14 12.3 0.4 0.95 9.7 0.0 2.7 3 0 0 3 3 3 0 Uperin family BCDHK_Adom3 PF10436.9 KKF96492.1 - 2.9e-59 199.6 0.5 5e-58 195.5 0.5 2.2 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KKF96492.1 - 2.4e-11 44.1 0.0 4.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KKF96492.1 - 0.079 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Stc1 PF12898.7 KKF96493.1 - 5.5e-09 36.5 4.8 9.9e-09 35.6 4.8 1.4 1 0 0 1 1 1 1 Stc1 domain PHD PF00628.29 KKF96493.1 - 0.0074 16.2 3.1 0.014 15.2 3.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKF96493.1 - 0.73 9.4 3.7 1.4 8.5 3.7 1.5 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.25 KKF96494.1 - 6.3e-56 189.6 0.0 9.7e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96494.1 - 2.7e-30 105.5 0.0 6.8e-29 100.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KKF96494.1 - 0.0006 18.9 0.0 0.0009 18.3 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 KKF96494.1 - 0.0025 16.8 0.0 0.0056 15.7 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKF96494.1 - 0.19 11.1 0.1 0.32 10.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AKAP7_NLS PF10469.9 KKF96495.1 - 1.5e-23 83.8 0.0 2.1e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Hpt PF01627.23 KKF96496.1 - 1.4e-09 38.0 0.5 2.4e-09 37.3 0.5 1.4 1 0 0 1 1 1 1 Hpt domain PPP4R2 PF09184.11 KKF96496.1 - 0.0024 17.5 10.2 0.0025 17.5 10.2 1.2 1 0 0 1 1 1 1 PPP4R2 Sigma70_ner PF04546.13 KKF96496.1 - 0.0064 16.4 18.2 0.01 15.7 16.3 2.0 2 0 0 2 2 2 1 Sigma-70, non-essential region DUF4820 PF16091.5 KKF96496.1 - 0.017 14.5 2.2 0.027 13.9 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Mpp10 PF04006.12 KKF96496.1 - 0.024 13.1 18.4 0.028 12.9 18.4 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 KKF96496.1 - 0.056 12.9 16.1 0.059 12.8 16.1 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KKF96496.1 - 0.19 9.9 19.5 0.21 9.8 19.5 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KKF96496.1 - 0.32 10.3 19.0 0.47 9.7 19.0 1.3 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 KKF96496.1 - 0.58 9.5 17.6 0.71 9.2 17.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 KKF96496.1 - 0.63 9.0 4.5 0.81 8.6 4.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) YL1 PF05764.13 KKF96496.1 - 0.66 10.0 21.5 0.83 9.7 21.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KKF96496.1 - 0.84 7.8 15.6 1.3 7.2 15.3 1.5 2 0 0 2 2 2 0 CDC45-like protein RRN3 PF05327.11 KKF96496.1 - 2.6 6.5 12.4 3.3 6.1 12.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.11 KKF96496.1 - 6 4.8 8.7 6.5 4.7 8.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen bZIP_1 PF00170.21 KKF96497.1 - 6.4e-09 35.8 11.1 6.4e-09 35.8 11.1 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KKF96497.1 - 0.015 15.4 10.6 0.015 15.4 10.6 2.4 2 0 0 2 2 2 0 Basic region leucine zipper ZapB PF06005.12 KKF96497.1 - 0.026 15.0 1.8 0.026 15.0 1.8 3.6 3 1 0 3 3 3 0 Cell division protein ZapB SDA1 PF05285.12 KKF96498.1 - 1.7e-85 287.6 65.1 2.6e-85 286.9 57.9 3.1 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 KKF96498.1 - 3.6e-21 75.2 0.1 8e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 NUC130/3NT domain DUF3669 PF12417.8 KKF96499.1 - 0.093 13.0 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Zinc finger protein Fungal_trans_2 PF11951.8 KKF96500.1 - 2.5e-56 191.1 0.1 3.5e-56 190.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF96500.1 - 2e-07 31.0 11.7 3.3e-07 30.3 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HATPase_c_3 PF13589.6 KKF96501.1 - 1.9e-10 40.7 0.0 2.3e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KKF96501.1 - 0.0015 19.0 0.0 0.0018 18.8 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPK PF03770.16 KKF96503.1 - 3.1e-55 187.1 0.0 4.1e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase LRR_4 PF12799.7 KKF96505.1 - 8e-23 80.1 39.6 2.8e-07 30.7 5.9 8.9 6 3 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKF96505.1 - 7.8e-15 54.4 42.0 2.3e-05 24.0 3.5 7.6 2 2 7 9 9 9 7 Leucine rich repeat LRR_9 PF14580.6 KKF96505.1 - 1.3e-07 31.3 13.1 0.014 14.9 0.5 3.9 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KKF96505.1 - 0.083 13.0 14.3 5.4 7.3 0.6 7.5 7 0 0 7 7 7 0 Leucine Rich repeat RabGAP-TBC PF00566.18 KKF96506.1 - 4.1e-45 154.1 0.0 7.5e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ECH_1 PF00378.20 KKF96507.1 - 1.2e-22 80.5 0.0 1.5e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKF96507.1 - 4.6e-10 39.5 0.0 5.8e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glycos_transf_1 PF00534.20 KKF96508.1 - 1.4e-33 115.8 0.0 2.3e-31 108.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKF96508.1 - 2.1e-17 63.7 0.0 4.7e-17 62.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KKF96508.1 - 1.4e-15 57.9 0.2 3.8e-15 56.5 0.2 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KKF96508.1 - 2.1e-08 34.8 1.5 2e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 KKF96508.1 - 0.00048 20.2 1.0 0.61 10.1 1.0 3.4 1 1 0 1 1 1 1 ALG11 mannosyltransferase N-terminus DUF1796 PF08795.10 KKF96508.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Pkinase PF00069.25 KKF96509.1 - 1.2e-36 126.4 0.1 3.1e-19 69.4 0.0 2.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96509.1 - 4.6e-15 55.6 0.8 2.1e-09 37.0 0.0 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase Mucin PF01456.17 KKF96509.1 - 5.2 7.1 29.7 10 6.1 29.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein LicD PF04991.13 KKF96511.1 - 4.5e-22 79.3 7.9 1.6e-16 61.1 2.1 2.1 1 1 1 2 2 2 2 LicD family WLM PF08325.10 KKF96512.1 - 1.3e-35 123.3 7.9 4.8e-35 121.4 6.5 2.3 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 KKF96512.1 - 0.0036 17.4 2.4 0.0091 16.1 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 ER_lumen_recept PF00810.18 KKF96513.1 - 1.8e-52 178.1 7.8 1.8e-52 178.1 7.8 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KKF96513.1 - 0.057 13.2 11.0 0.33 10.8 0.2 3.6 4 0 0 4 4 4 0 PQ loop repeat RPN6_N PF18055.1 KKF96514.1 - 1.8e-39 134.7 0.2 8.8e-39 132.5 0.1 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KKF96514.1 - 5.6e-20 71.8 2.2 1.6e-19 70.4 0.1 2.5 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 KKF96514.1 - 1.1e-12 47.4 0.6 2.8e-12 46.1 0.6 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 KKF96514.1 - 0.00027 21.1 17.5 0.013 15.8 3.8 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KKF96514.1 - 0.0049 16.3 5.3 0.008 15.6 1.3 2.3 2 0 0 2 2 2 1 MalT-like TPR region DDRGK PF09756.9 KKF96514.1 - 0.0049 16.5 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 DDRGK domain DUF3496 PF12001.8 KKF96514.1 - 0.0057 17.0 0.6 0.025 14.9 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3496) Tocopherol_cycl PF14249.6 KKF96514.1 - 0.084 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Tocopherol cyclase CorA PF01544.18 KKF96514.1 - 0.27 10.5 3.1 0.92 8.8 0.2 2.7 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Med2 PF11214.8 KKF96514.1 - 0.37 11.0 2.8 0.44 10.7 0.3 2.4 3 0 0 3 3 3 0 Mediator complex subunit 2 TPR_7 PF13176.6 KKF96514.1 - 0.58 10.3 11.7 2.4 8.4 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKF96514.1 - 4 8.3 0.0 4 8.3 0.0 4.6 5 1 0 5 5 4 0 Tetratricopeptide repeat Mito_carr PF00153.27 KKF96516.1 - 6.3e-48 160.7 5.8 4.5e-17 61.8 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Mak10 PF04112.13 KKF96517.1 - 4.1e-55 185.8 0.1 7.2e-55 185.0 0.1 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Glyco_hydro_72 PF03198.14 KKF96518.1 - 7.3e-92 308.0 1.6 1.1e-91 307.4 1.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase ATP-synt_Eps PF04627.13 KKF96518.1 - 1e-15 57.4 0.9 2.1e-15 56.4 0.9 1.5 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Glyco_hydro_2_C PF02836.17 KKF96518.1 - 0.021 14.0 0.1 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Phytase-like PF13449.6 KKF96519.1 - 1.4e-05 25.2 0.0 2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase RRT14 PF17075.5 KKF96519.1 - 0.11 12.6 0.4 0.16 12.1 0.4 1.2 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 DBD_Tnp_Mut PF03108.15 KKF96520.1 - 0.0003 20.7 2.3 0.36 10.9 0.0 2.5 2 0 0 2 2 2 2 MuDR family transposase DUF4407 PF14362.6 KKF96520.1 - 5.8 6.2 14.9 0.68 9.2 10.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) adh_short PF00106.25 KKF96521.1 - 1.4e-38 132.4 0.3 2e-38 131.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF96521.1 - 1.1e-28 100.4 0.0 1.4e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF96521.1 - 1.5e-09 38.0 3.2 3.5e-08 33.5 3.2 2.1 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKF96521.1 - 0.023 14.1 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KKF96521.1 - 0.082 12.4 0.2 0.12 11.8 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sof1 PF04158.14 KKF96522.1 - 2.4e-31 107.9 16.3 4.1e-31 107.1 16.3 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KKF96522.1 - 4.1e-26 90.7 16.1 1.9e-06 28.5 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF96522.1 - 2.8e-11 43.5 1.9 0.0061 16.8 0.4 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KKF96522.1 - 0.0042 17.1 0.0 5 7.2 0.0 4.3 2 2 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 KKF96522.1 - 0.013 14.4 0.0 0.2 10.6 0.0 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KKF96522.1 - 0.06 12.3 0.8 1.8 7.4 0.1 2.5 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain RNA_pol_A_bac PF01000.26 KKF96523.1 - 5.6e-33 113.7 0.0 8.9e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KKF96523.1 - 4.8e-17 61.2 0.0 6.7e-17 60.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.27 KKF96524.1 - 1.8e-48 162.4 1.3 5.7e-17 61.4 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3956 PF13104.6 KKF96524.1 - 0.2 11.9 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) tRNA-synt_2d PF01409.20 KKF96525.1 - 3e-49 167.7 0.4 1.5e-25 90.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KKF96525.1 - 7.6e-24 84.0 0.0 2e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain CTP_transf_like PF01467.26 KKF96527.1 - 8.2e-21 74.7 0.0 1e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like LZ3wCH PF18517.1 KKF96527.1 - 0.21 11.7 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Leucine zipper with capping helix domain MAP65_ASE1 PF03999.12 KKF96528.1 - 2.7e-74 251.0 13.1 5.4e-74 250.0 13.1 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Cas_DxTHG PF09455.10 KKF96528.1 - 0.0044 16.6 2.5 0.016 14.8 2.5 1.9 1 1 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family Baculo_PEP_C PF04513.12 KKF96528.1 - 0.0076 16.3 0.3 4.9 7.2 0.1 3.0 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4962 PF16332.5 KKF96528.1 - 0.12 10.9 0.4 0.26 9.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) ISPD_C PF18706.1 KKF96528.1 - 0.13 11.9 0.5 0.32 10.6 0.5 1.6 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Spectrin PF00435.21 KKF96528.1 - 0.27 11.7 23.0 0.21 12.1 2.9 4.9 3 2 0 4 4 4 0 Spectrin repeat DUF948 PF06103.11 KKF96528.1 - 0.54 10.5 2.4 5.5 7.3 0.2 3.6 6 0 0 6 6 5 0 Bacterial protein of unknown function (DUF948) LXG PF04740.12 KKF96528.1 - 0.89 9.2 10.7 0.087 12.5 0.6 3.1 4 0 0 4 4 4 0 LXG domain of WXG superfamily GCN5L1 PF06320.13 KKF96528.1 - 1.3 9.1 6.4 0.41 10.8 0.5 2.9 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Prominin PF05478.11 KKF96528.1 - 3.5 5.5 4.1 3.4 5.5 0.2 2.2 2 0 0 2 2 2 0 Prominin IFT20 PF14931.6 KKF96528.1 - 7.1 6.8 12.1 17 5.6 2.6 4.4 4 1 0 4 4 4 0 Intraflagellar transport complex B, subunit 20 EF-hand_4 PF12763.7 KKF96529.1 - 2.4e-05 24.2 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Amelotin PF15757.5 KKF96529.1 - 0.081 12.5 0.7 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Amelotin Metallophos PF00149.28 KKF96530.1 - 2.6e-10 41.1 0.0 1.2e-09 39.0 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKF96530.1 - 9.7e-06 25.9 0.0 0.039 14.1 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain APH PF01636.23 KKF96531.1 - 8.1e-17 61.9 0.0 1.4e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKF96531.1 - 0.011 15.4 1.5 0.013 15.1 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Fmp27 PF10344.9 KKF96533.1 - 1.6e-186 622.2 0.0 3.2e-186 621.2 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 KKF96533.1 - 1.4e-160 535.4 0.1 4e-160 533.8 0.0 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 KKF96533.1 - 3.4e-157 524.2 1.2 3.6e-126 421.8 0.1 4.2 3 1 1 4 4 4 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 KKF96533.1 - 2.1e-54 183.9 0.0 4.4e-54 182.8 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KKF96533.1 - 3.3e-48 163.5 0.0 9e-48 162.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KKF96533.1 - 1.2e-29 103.1 0.0 6.8e-29 100.6 0.0 2.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain GTP_EFTU PF00009.27 KKF96534.1 - 1.9e-58 197.3 0.0 3.3e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KKF96534.1 - 1.7e-15 56.8 0.0 7.8e-15 54.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKF96534.1 - 3.5e-10 40.1 0.0 8.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KKF96534.1 - 2.1e-08 34.1 0.0 5.8e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KKF96534.1 - 7.3e-05 22.5 0.0 0.00049 19.9 0.0 2.4 2 1 0 2 2 2 1 Elongation factor G, domain IV Paf67 PF10255.9 KKF96535.1 - 1.2e-150 502.0 0.0 1.5e-150 501.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KKF96535.1 - 0.043 13.9 0.0 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ABA_GPCR PF12430.8 KKF96536.1 - 1.9e-51 174.4 1.1 1.9e-51 174.4 1.1 2.4 3 0 0 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KKF96536.1 - 9.8e-18 64.0 0.2 4e-17 62.1 0.2 2.1 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF898 PF05987.13 KKF96536.1 - 4.8 6.1 17.1 0.0044 16.1 5.2 2.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF898) RRM_1 PF00076.22 KKF96537.1 - 1.2e-11 44.3 0.0 3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF533 PF04391.12 KKF96538.1 - 0.15 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) JAB PF01398.21 KKF96539.1 - 5.5e-32 110.2 0.1 1.1e-31 109.2 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease LDB19 PF13002.7 KKF96539.1 - 2.4e-27 95.9 1.4 1.1e-26 93.7 1.4 2.0 1 1 0 1 1 1 1 Arrestin_N terminal like CSN5_C PF18323.1 KKF96539.1 - 6.9e-05 23.7 2.5 6.9e-05 23.7 2.5 2.9 3 0 0 3 3 3 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KKF96539.1 - 0.00064 19.5 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Arrestin_C PF02752.22 KKF96539.1 - 0.00094 19.6 0.0 0.2 12.1 0.0 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain UPF0172 PF03665.13 KKF96539.1 - 0.017 15.2 0.1 0.06 13.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) LIM PF00412.22 KKF96539.1 - 0.066 13.5 0.7 0.13 12.5 0.7 1.4 1 0 0 1 1 1 0 LIM domain DUF4698 PF15769.5 KKF96539.1 - 5.3 6.0 9.4 0.099 11.7 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) Abhydrolase_3 PF07859.13 KKF96540.1 - 1.7e-31 109.7 0.0 2.1e-21 76.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKF96540.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase DUF1168 PF06658.12 KKF96540.1 - 0.54 10.1 3.3 0.46 10.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Bys1 PF04681.12 KKF96541.1 - 2.1e-11 44.0 0.2 2.7e-11 43.7 0.2 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Aminotran_3 PF00202.21 KKF96542.1 - 8.4e-108 360.6 0.0 1.1e-107 360.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Phage_TAC_6 PF09550.10 KKF96542.1 - 0.074 13.5 0.0 0.3 11.6 0.1 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Ufd2P_core PF10408.9 KKF96543.1 - 1.4e-177 592.1 12.5 3.4e-102 343.1 4.7 2.2 1 1 1 2 2 2 2 Ubiquitin elongating factor core U-box PF04564.15 KKF96543.1 - 9.3e-24 83.4 1.3 9.4e-23 80.2 0.7 2.8 2 0 0 2 2 2 1 U-box domain Clathrin PF00637.20 KKF96544.1 - 4.5e-24 85.0 0.7 2.6e-20 72.7 0.1 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.8 KKF96544.1 - 1.3e-18 67.0 0.0 3e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal DUF3446 PF11928.8 KKF96545.1 - 8 6.8 14.0 0.26 11.6 5.7 2.7 3 0 0 3 3 3 0 Early growth response N-terminal domain 6PF2K PF01591.18 KKF96546.1 - 3e-47 160.8 0.0 4.6e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KKF96546.1 - 3e-29 102.1 0.1 1.1e-24 87.2 0.0 2.8 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) SCIMP PF15050.6 KKF96546.1 - 0.038 14.4 0.2 0.077 13.5 0.2 1.4 1 0 0 1 1 1 0 SCIMP protein CARD PF00619.21 KKF96546.1 - 0.043 13.9 1.5 0.16 12.0 0.4 2.4 2 1 0 2 2 2 0 Caspase recruitment domain PhoU PF01895.19 KKF96546.1 - 0.061 13.8 0.5 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 PhoU domain dCMP_cyt_deam_1 PF00383.23 KKF96547.1 - 1.7e-10 40.6 0.0 3.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKF96547.1 - 0.001 18.8 0.8 0.026 14.3 0.1 2.3 2 0 0 2 2 2 1 MafB19-like deaminase Cauli_VI PF01693.16 KKF96548.1 - 9.3e-39 131.5 4.4 2.6e-21 75.6 0.5 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KKF96548.1 - 4e-35 121.1 0.0 6.8e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 RNase H PDEase_I_N PF08499.12 KKF96548.1 - 0.061 13.2 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Ank_5 PF13857.6 KKF96549.1 - 9.5e-12 44.9 0.3 2.3e-11 43.7 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KKF96549.1 - 1.2e-07 31.8 0.1 1e-05 25.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KKF96549.1 - 6.2e-07 29.9 0.1 2.5e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKF96549.1 - 1.4e-05 25.5 0.0 4.8e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKF96549.1 - 1.5e-05 25.0 0.3 0.00019 21.6 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Velvet PF11754.8 KKF96550.1 - 3.9e-56 190.8 0.0 7.3e-34 117.8 0.0 2.1 1 1 1 2 2 2 2 Velvet factor RasGEF PF00617.19 KKF96552.1 - 3.1e-49 167.5 0.3 4.5e-49 167.0 0.3 1.2 1 0 0 1 1 1 1 RasGEF domain AAA PF00004.29 KKF96553.1 - 6.8e-50 168.9 0.0 1.6e-37 128.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKF96553.1 - 5e-09 36.5 0.2 0.0067 16.7 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KKF96553.1 - 7.9e-08 32.0 0.3 2.4e-07 30.5 0.3 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 KKF96553.1 - 1.3e-07 32.1 0.1 0.005 17.2 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 KKF96553.1 - 5.6e-07 29.8 0.0 2.3e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 KKF96553.1 - 1.2e-06 28.2 0.4 1.3e-05 24.9 0.1 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 KKF96553.1 - 1.3e-06 28.5 0.0 0.015 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KKF96553.1 - 1.3e-06 27.9 0.0 0.04 13.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain ATPase_2 PF01637.18 KKF96553.1 - 1.9e-06 28.0 0.0 2.1 8.2 0.0 4.2 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KKF96553.1 - 2e-06 27.9 0.0 0.0041 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKF96553.1 - 5.4e-06 26.6 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KKF96553.1 - 9.1e-06 25.3 0.7 0.027 14.0 0.0 3.5 4 0 0 4 4 3 1 P-loop containing dynein motor region AAA_18 PF13238.6 KKF96553.1 - 9.7e-06 26.2 0.0 0.12 12.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 KKF96553.1 - 1.1e-05 25.4 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KKF96553.1 - 2.3e-05 23.9 0.1 0.0028 17.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KKF96553.1 - 4.2e-05 23.4 0.0 0.43 10.4 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKF96553.1 - 4.7e-05 23.2 0.1 0.032 14.0 0.1 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KKF96553.1 - 0.00018 21.9 0.0 0.062 13.7 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KKF96553.1 - 0.00029 20.6 0.0 0.017 14.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKF96553.1 - 0.00034 20.4 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ResIII PF04851.15 KKF96553.1 - 0.0011 19.0 0.1 2 8.4 0.0 2.6 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 KKF96553.1 - 0.0012 18.5 0.1 0.79 9.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 KKF96553.1 - 0.0016 19.0 0.0 0.45 11.0 0.1 2.7 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 KKF96553.1 - 0.0017 18.3 1.4 2.7 7.9 0.0 3.5 4 0 0 4 4 3 1 NACHT domain ATPase PF06745.13 KKF96553.1 - 0.0022 17.4 0.1 0.071 12.4 0.1 2.6 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.22 KKF96553.1 - 0.0033 16.7 0.1 1.3 8.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 KKF96553.1 - 0.0035 17.1 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 KKF96553.1 - 0.0065 16.4 0.2 0.035 14.1 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain DNA_pol3_delta2 PF13177.6 KKF96553.1 - 0.012 15.4 0.1 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 DNA polymerase III, delta subunit SRP54 PF00448.22 KKF96553.1 - 0.014 15.0 0.1 0.87 9.2 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Parvo_NS1 PF01057.17 KKF96553.1 - 0.015 14.4 0.0 0.96 8.5 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KKF96553.1 - 0.024 14.9 0.0 6.6 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKF96553.1 - 0.027 13.7 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin CDC48_N PF02359.18 KKF96553.1 - 0.029 14.5 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain DUF815 PF05673.13 KKF96553.1 - 0.036 13.2 0.0 1.6 7.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KKF96553.1 - 0.04 13.5 0.5 7.8 6.0 0.0 3.5 3 1 1 4 4 4 0 AAA domain PhoH PF02562.16 KKF96553.1 - 0.041 13.3 0.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 KKF96553.1 - 0.044 13.6 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Bep_C_terminal PF17841.1 KKF96553.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) DUF2075 PF09848.9 KKF96553.1 - 0.074 12.3 0.0 4.9 6.3 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.18 KKF96553.1 - 0.095 12.5 0.0 23 4.7 0.0 2.7 3 0 0 3 3 2 0 Bacterial dnaA protein AAA_17 PF13207.6 KKF96553.1 - 0.097 13.1 0.0 23 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Spt20 PF12090.8 KKF96556.1 - 6.3e-42 143.8 0.4 6.3e-42 143.8 0.4 8.7 4 2 3 7 7 7 1 Spt20 family ATG27 PF09451.10 KKF96557.1 - 1.6e-76 257.7 0.0 2.5e-76 257.0 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KKF96557.1 - 0.00064 19.8 0.2 0.014 15.5 0.1 2.7 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat Pyridoxal_deC PF00282.19 KKF96558.1 - 1.5e-73 247.7 0.0 2.1e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KKF96558.1 - 1.3e-05 24.4 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKF96558.1 - 0.0084 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family PAS_9 PF13426.7 KKF96559.1 - 2.9e-14 53.2 0.0 5.2e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KKF96559.1 - 0.019 14.9 0.0 0.53 10.3 0.0 2.4 2 0 0 2 2 2 0 PAS fold Pmp3 PF01679.17 KKF96560.1 - 1e-19 70.5 8.3 1.4e-19 70.0 8.3 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.10 KKF96561.1 - 2.7e-85 287.0 0.0 3.7e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.16 KKF96562.1 - 4.1e-47 160.6 0.0 6.7e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase SNARE PF05739.19 KKF96562.1 - 0.17 11.9 0.7 0.31 11.1 0.7 1.4 1 0 0 1 1 1 0 SNARE domain CENP-B_dimeris PF09026.10 KKF96562.1 - 4.4 7.8 11.7 1.5 9.3 2.4 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CLP1_P PF16575.5 KKF96563.1 - 3e-37 128.2 0.0 5e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KKF96563.1 - 3.8e-29 100.8 0.0 6.3e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KKF96563.1 - 9.2e-19 68.0 0.0 2.3e-18 66.7 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.23 KKF96563.1 - 8.8e-08 32.2 0.0 0.0025 17.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KKF96563.1 - 7e-07 29.3 0.0 4.6e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 KKF96563.1 - 0.00044 19.9 0.0 0.66 9.6 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KKF96563.1 - 0.00048 19.9 0.0 0.0016 18.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKF96563.1 - 0.0024 18.0 0.0 0.0064 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF96563.1 - 0.0037 17.6 0.0 0.94 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KKF96563.1 - 0.0045 16.9 0.0 0.19 11.6 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 KKF96563.1 - 0.0062 16.3 0.0 1.6 8.5 0.0 2.5 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KKF96563.1 - 0.0078 15.7 0.0 0.045 13.2 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit CbiA PF01656.23 KKF96563.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KKF96563.1 - 0.022 15.1 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KKF96563.1 - 0.028 14.9 0.0 0.071 13.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain FeoB_N PF02421.18 KKF96563.1 - 0.029 13.9 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 KKF96563.1 - 0.041 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKF96563.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KKF96563.1 - 0.086 12.4 0.0 0.64 9.5 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_35 PF14516.6 KKF96563.1 - 0.09 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.18 KKF96563.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.10 KKF96563.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TniB PF05621.11 KKF96563.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 KKF96563.1 - 0.17 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KKF96563.1 - 0.17 12.1 0.0 0.49 10.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain OB_NTP_bind PF07717.16 KKF96564.1 - 9.2e-24 83.6 0.0 1.9e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KKF96564.1 - 1.3e-22 80.1 0.0 1.3e-22 80.1 0.0 2.7 3 1 0 3 3 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKF96564.1 - 6.9e-14 52.1 0.0 1.9e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KKF96564.1 - 2.5e-12 47.0 1.3 4.7e-12 46.1 1.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 KKF96564.1 - 4.8e-06 26.9 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KKF96564.1 - 1e-05 25.4 0.9 3.8e-05 23.5 0.9 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KKF96564.1 - 0.00011 21.9 0.1 0.00028 20.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKF96564.1 - 0.00015 20.9 0.0 0.00034 19.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 KKF96564.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KKF96564.1 - 0.011 16.1 0.1 0.024 15.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKF96564.1 - 0.038 14.0 1.4 0.28 11.2 0.1 2.8 3 1 0 3 3 2 0 AAA domain PhoH PF02562.16 KKF96564.1 - 0.049 13.1 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein Microtub_bd PF16796.5 KKF96564.1 - 0.11 12.4 0.2 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Microtubule binding AAA_7 PF12775.7 KKF96564.1 - 0.16 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Herpes_ori_bp PF02399.15 KKF96564.1 - 0.19 9.7 0.1 0.31 9.0 0.1 1.2 1 0 0 1 1 1 0 Origin of replication binding protein ABC_tran PF00005.27 KKF96564.1 - 0.21 12.1 3.2 0.28 11.7 0.2 2.7 2 1 0 3 3 3 0 ABC transporter NUC153 PF08159.12 KKF96565.1 - 1e-11 44.4 13.6 3.7e-11 42.6 0.1 3.7 3 0 0 3 3 3 2 NUC153 domain Git3 PF11710.8 KKF96566.1 - 1.9e-52 178.0 13.7 3.1e-52 177.3 13.7 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KKF96566.1 - 4.6e-19 68.2 0.1 4.6e-19 68.2 0.1 2.9 3 1 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term STE3 PF02076.15 KKF96566.1 - 0.0033 16.7 3.2 0.0033 16.7 3.2 2.3 2 1 0 3 3 3 1 Pheromone A receptor GATase PF00117.28 KKF96567.1 - 2.6e-13 50.2 0.0 3.5e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KKF96567.1 - 0.0086 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KKF96567.1 - 0.026 14.3 0.7 0.26 11.0 0.7 2.4 1 1 0 1 1 1 0 Peptidase C26 DHHA2 PF02833.14 KKF96568.1 - 9.7e-34 116.6 0.0 1.4e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KKF96568.1 - 1.6e-08 34.7 0.0 2.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DHH family RsfS PF02410.15 KKF96569.1 - 1.3e-11 44.8 0.0 3e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation RNA_pol PF00940.19 KKF96570.1 - 9.2e-183 607.8 0.0 1.5e-182 607.1 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KKF96570.1 - 2.1e-89 300.2 7.0 2.1e-89 300.2 7.0 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal tRNA_bind PF01588.20 KKF96571.1 - 6.4e-24 83.9 0.1 1.3e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KKF96571.1 - 0.00054 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKF96571.1 - 0.011 16.0 3.7 0.029 14.6 0.0 2.9 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain SNF2_N PF00176.23 KKF96572.1 - 1.4e-64 218.1 0.1 3.1e-64 216.9 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKF96572.1 - 9.7e-20 71.0 0.0 2.7e-19 69.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF96572.1 - 3.1e-07 30.6 0.0 9.6e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KKF96572.1 - 0.0085 15.8 0.0 0.043 13.5 0.0 2.0 1 1 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KKF96572.1 - 0.021 14.1 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PRIMA1 PF16101.5 KKF96572.1 - 0.3 11.1 6.3 0.64 10.1 6.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF2605 PF10792.9 KKF96572.1 - 0.54 10.2 3.1 1.7 8.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) Cu-oxidase_2 PF07731.14 KKF96573.1 - 3e-42 143.6 11.1 1.9e-40 137.8 0.2 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KKF96573.1 - 7.8e-37 125.9 1.7 7.8e-37 125.9 1.7 3.9 5 1 0 5 5 5 1 Multicopper oxidase Cu-oxidase PF00394.22 KKF96573.1 - 1.9e-31 109.3 0.3 9e-31 107.1 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Epimerase PF01370.21 KKF96574.1 - 4.4e-44 150.8 0.0 5.8e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKF96574.1 - 2e-43 149.1 0.0 3.6e-43 148.2 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKF96574.1 - 3.6e-16 59.0 0.0 6.6e-16 58.1 0.1 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KKF96574.1 - 4e-14 52.5 0.1 2.8e-12 46.4 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KKF96574.1 - 1.6e-11 43.8 0.0 2.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KKF96574.1 - 8.7e-11 41.6 0.1 1.4e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KKF96574.1 - 0.0001 21.6 0.2 0.0086 15.3 0.2 2.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 KKF96574.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KKF96574.1 - 0.0012 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KKF96574.1 - 0.0058 16.6 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KKF96574.1 - 0.021 15.1 0.1 0.038 14.3 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KKF96574.1 - 0.073 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Chol_subst-bind PF09129.11 KKF96574.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding ADH_zinc_N PF00107.26 KKF96575.1 - 2.5e-27 95.4 0.4 4e-27 94.7 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKF96575.1 - 7.8e-22 78.8 0.1 1.6e-21 77.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKF96575.1 - 5.6e-10 39.1 0.0 1.4e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KKF96575.1 - 0.006 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase HlyD PF00529.20 KKF96575.1 - 0.011 15.6 2.2 2.3 8.1 1.7 2.4 1 1 1 2 2 2 0 HlyD membrane-fusion protein of T1SS adh_short PF00106.25 KKF96575.1 - 0.033 13.6 1.8 0.058 12.8 1.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Ank_2 PF12796.7 KKF96576.1 - 2.3e-35 121.0 15.0 3.5e-05 24.3 0.0 12.9 7 5 2 11 11 11 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKF96576.1 - 1.2e-22 79.9 13.7 0.015 15.9 0.0 14.6 14 2 2 16 16 16 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKF96576.1 - 1.2e-16 60.5 2.8 8.2e-05 22.8 0.1 9.9 10 1 1 11 11 11 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKF96576.1 - 2.4e-15 55.1 15.8 0.002 18.5 0.0 15.3 19 0 0 19 19 19 2 Ankyrin repeat Ank PF00023.30 KKF96576.1 - 2.2e-10 40.5 25.4 1.2e-05 25.5 0.0 13.4 15 1 0 15 15 15 1 Ankyrin repeat Pkinase PF00069.25 KKF96577.1 - 2.9e-09 36.7 0.0 3.6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KKF96577.1 - 2.5e-05 23.2 0.0 2.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KKF96577.1 - 6e-05 22.5 0.0 0.0001 21.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKF96577.1 - 0.00031 20.7 0.1 0.00038 20.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKF96577.1 - 0.00048 19.8 0.4 0.0007 19.2 0.4 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KKF96578.1 - 7.9e-22 77.9 0.0 2.5e-20 73.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96578.1 - 2.8e-06 26.8 0.0 0.065 12.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KKF96578.1 - 0.048 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKF96578.1 - 0.18 10.6 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Retrotran_gag_2 PF14223.6 KKF96579.1 - 1.1e-05 25.1 0.3 0.036 13.7 0.0 2.4 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KKF96579.1 - 0.16 11.7 0.9 0.28 10.9 0.9 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger MADF_DNA_bdg PF10545.9 KKF96579.1 - 7.1 7.0 8.1 14 6.1 0.2 3.7 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AAA_16 PF13191.6 KKF96580.1 - 2.5e-06 28.0 0.6 1.7e-05 25.3 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain Goodbye PF17109.5 KKF96580.1 - 1.7e-05 25.2 0.0 8.3e-05 23.0 0.0 2.2 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Torsin PF06309.11 KKF96580.1 - 0.094 12.8 0.0 1.3 9.2 0.0 2.7 3 0 0 3 3 3 0 Torsin AAA_22 PF13401.6 KKF96580.1 - 0.22 11.8 1.3 2.4 8.4 0.2 3.0 2 1 0 2 2 2 0 AAA domain RTA1 PF04479.13 KKF96581.1 - 7.5e-71 238.0 7.1 7.5e-71 238.0 7.1 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF4173 PF13777.6 KKF96581.1 - 5 6.5 13.3 0.29 10.5 6.8 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4173) Pec_lyase_C PF00544.19 KKF96582.1 - 4.7e-16 59.0 9.4 1.7e-14 54.0 9.4 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KKF96582.1 - 3.7e-06 26.9 19.0 0.00024 21.0 10.0 2.4 1 1 1 2 2 2 2 Right handed beta helix region SHR-BD PF06650.12 KKF96583.1 - 1.6e-88 296.6 0.0 1.4e-86 290.2 0.0 3.2 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 KKF96583.1 - 2.9e-84 282.5 1.7 5.8e-83 278.3 0.1 3.2 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 KKF96583.1 - 4.1e-83 278.4 12.1 1e-82 277.1 1.4 5.1 5 0 0 5 5 5 1 Repeating coiled region of VPS13 VPS13_C PF16909.5 KKF96583.1 - 1.6e-71 239.7 8.6 6e-67 224.9 2.9 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KKF96583.1 - 1.2e-37 128.5 0.0 4.3e-37 126.8 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KKF96583.1 - 4.6e-07 30.1 0.0 1.6e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain GlutR_dimer PF00745.20 KKF96583.1 - 0.26 11.8 1.8 0.84 10.1 1.8 1.9 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain CLASP_N PF12348.8 KKF96584.1 - 1.1e-05 25.1 0.1 0.0002 21.0 0.1 2.5 2 1 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.7 KKF96584.1 - 0.00054 20.0 0.0 0.044 13.8 0.0 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKF96584.1 - 0.0077 16.4 0.1 0.31 11.4 0.4 3.5 3 0 0 3 3 3 1 HEAT repeat TAN PF11640.8 KKF96584.1 - 0.099 12.8 0.0 0.099 12.8 0.0 2.6 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair UPF0242 PF06785.11 KKF96584.1 - 0.54 10.3 8.2 0.067 13.3 3.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Mod_r PF07200.13 KKF96584.1 - 0.68 10.0 9.1 2.2 8.4 9.1 1.8 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CENP-F_N PF10481.9 KKF96584.1 - 1.2 8.7 8.1 0.12 12.0 1.7 2.1 2 0 0 2 2 2 0 Cenp-F N-terminal domain YabA PF06156.13 KKF96584.1 - 3.3 8.4 8.0 33 5.2 8.2 2.4 1 1 0 1 1 1 0 Initiation control protein YabA Herpes_BLRF2 PF05812.12 KKF96584.1 - 4.6 7.4 9.1 1.8 8.7 5.6 2.1 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Syntaxin PF00804.25 KKF96584.1 - 5.2 6.7 10.1 0.12 12.0 2.6 2.1 3 0 0 3 3 3 0 Syntaxin HALZ PF02183.18 KKF96584.1 - 6.2 7.1 12.8 10 6.5 0.6 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper SEEEED PF14797.6 KKF96585.1 - 0.0023 18.1 25.3 0.0026 17.9 25.3 1.1 1 0 0 1 1 1 1 Serine-rich region of AP3B1, clathrin-adaptor complex AF-4 PF05110.13 KKF96585.1 - 0.054 11.6 21.4 0.057 11.5 21.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Striatin PF08232.12 KKF96585.1 - 1 9.9 10.7 1.3 9.6 10.7 1.1 1 0 0 1 1 1 0 Striatin family DUF4614 PF15391.6 KKF96585.1 - 2.6 8.0 17.4 3.3 7.7 17.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF3405 PF11885.8 KKF96585.1 - 3.3 6.2 11.0 3.8 6.0 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Pex14_N PF04695.13 KKF96585.1 - 4.1 8.0 8.7 5.1 7.7 8.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PNISR PF15996.5 KKF96585.1 - 6.5 7.0 10.0 7.4 6.8 10.0 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR ASD2 PF08687.11 KKF96585.1 - 6.9 6.1 10.4 7.3 6.1 10.4 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Gti1_Pac2 PF09729.9 KKF96585.1 - 8.6 6.4 17.9 9.8 6.2 17.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family GCFC PF07842.12 KKF96586.1 - 5.6e-29 101.6 0.0 6.2e-23 81.8 0.0 2.6 2 1 1 3 3 3 2 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KKF96586.1 - 8.1e-14 51.2 2.3 2.5e-13 49.7 2.3 1.9 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 KKF96586.1 - 1.1e-08 35.3 13.0 1.1e-08 35.3 13.0 3.5 4 0 0 4 4 4 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 KKF96586.1 - 3.4e-07 30.2 0.6 1.3e-06 28.4 0.6 2.0 1 0 0 1 1 1 1 G-patch domain SAPS PF04499.15 KKF96587.1 - 3.3e-180 600.1 0.9 3.3e-180 600.1 0.9 2.8 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein PRIMA1 PF16101.5 KKF96587.1 - 4.2 7.4 9.0 9.1 6.3 9.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Nucleos_tra2_C PF07662.13 KKF96588.1 - 1e-63 215.0 7.0 1e-63 215.0 7.0 2.6 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KKF96588.1 - 4e-22 78.6 2.4 4e-22 78.6 2.4 4.0 4 1 1 5 5 5 1 Na+ dependent nucleoside transporter N-terminus DUF3087 PF11286.8 KKF96588.1 - 1.9 7.9 5.2 0.47 9.9 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3087) Gate PF07670.14 KKF96588.1 - 3.9 7.8 20.8 0.18 12.1 6.7 3.3 3 1 0 3 3 3 0 Nucleoside recognition Mating_C PF12737.7 KKF96589.1 - 0.079 12.2 3.7 0.19 11.0 3.7 1.6 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Med3 PF11593.8 KKF96590.1 - 1.6e-06 27.6 3.7 1.6e-06 27.6 3.7 1.6 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal DUF2722 PF10846.8 KKF96590.1 - 0.078 11.9 2.6 0.12 11.3 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CCAP PF11105.8 KKF96590.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a DUF1741 PF08427.10 KKF96591.1 - 5.2e-82 275.0 0.2 1.6e-81 273.4 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) MgsA_C PF12002.8 KKF96592.1 - 5.1e-60 202.2 0.3 3.1e-59 199.7 0.0 2.0 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KKF96592.1 - 5.4e-21 74.7 0.3 1.6e-20 73.2 0.3 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KKF96592.1 - 4.5e-17 62.7 0.3 1.6e-16 60.9 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKF96592.1 - 6.4e-09 35.7 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKF96592.1 - 3.3e-07 30.4 0.0 6.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KKF96592.1 - 4.2e-06 26.6 0.1 9.2e-05 22.2 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KKF96592.1 - 8e-06 26.3 2.9 0.0038 17.6 0.0 3.4 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KKF96592.1 - 3.5e-05 24.1 0.3 0.0014 18.9 0.2 3.0 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 KKF96592.1 - 5.3e-05 23.3 0.0 0.00014 21.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KKF96592.1 - 0.00014 21.3 0.1 0.58 9.5 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 KKF96592.1 - 0.0014 18.4 0.1 0.0043 16.8 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase AAA_33 PF13671.6 KKF96592.1 - 0.0015 18.7 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KKF96592.1 - 0.0027 16.9 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KKF96592.1 - 0.0059 17.2 0.1 0.023 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KKF96592.1 - 0.0067 15.7 0.1 0.022 14.0 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain SKI PF01202.22 KKF96592.1 - 0.0083 16.3 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate kinase AAA_24 PF13479.6 KKF96592.1 - 0.0087 15.8 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KKF96592.1 - 0.0088 16.2 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 KKF96592.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.6 KKF96592.1 - 0.018 14.8 0.0 0.087 12.6 0.0 1.9 1 1 1 2 2 2 0 DNA polymerase III, delta subunit AAA_6 PF12774.7 KKF96592.1 - 0.023 13.6 0.7 2.3 7.1 0.3 2.2 1 1 1 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Rad17 PF03215.15 KKF96592.1 - 0.03 14.3 0.1 0.18 11.7 0.0 2.0 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_11 PF13086.6 KKF96592.1 - 0.031 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KKF96592.1 - 0.034 14.0 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KKF96592.1 - 0.04 14.4 0.0 0.088 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 KKF96592.1 - 0.042 13.8 3.3 0.62 10.1 0.1 2.5 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit IPT PF01745.16 KKF96592.1 - 0.043 13.2 0.1 0.083 12.3 0.1 1.5 1 0 0 1 1 1 0 Isopentenyl transferase AAA_23 PF13476.6 KKF96592.1 - 0.047 14.2 0.8 0.073 13.6 0.8 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKF96592.1 - 0.054 13.0 0.1 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KKF96592.1 - 0.086 13.2 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 KKF96592.1 - 0.35 11.2 2.0 2.6 8.4 1.2 2.7 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 KKF96592.1 - 0.86 9.8 4.0 0.91 9.7 0.7 2.6 2 1 0 2 2 2 0 AAA domain Fe-S_biosyn PF01521.20 KKF96593.1 - 6.2e-20 71.4 0.0 8.8e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis LPMO_10 PF03067.15 KKF96594.1 - 5.9e-16 59.7 0.4 1e-15 58.9 0.4 1.4 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading SOG2 PF10428.9 KKF96594.1 - 1 8.5 9.7 1.1 8.3 9.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Abhydrolase_1 PF00561.20 KKF96595.1 - 9.6e-16 58.2 0.1 8.4e-14 51.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKF96595.1 - 6.7e-12 46.5 0.0 8.1e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKF96595.1 - 1.4e-07 31.0 0.0 2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PI-PLC-X PF00388.19 KKF96596.1 - 7.4e-44 148.8 0.0 1.2e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KKF96596.1 - 6.2e-37 126.5 0.0 1.1e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Herpes_UL55 PF04537.12 KKF96596.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus UL55 protein C2 PF00168.30 KKF96596.1 - 0.026 14.8 0.0 0.074 13.4 0.0 1.8 1 0 0 1 1 1 0 C2 domain Aminotran_1_2 PF00155.21 KKF96597.1 - 1.6e-90 303.9 0.0 1.9e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Paz_1 PF18349.1 KKF96597.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 PAZ domain Ribosomal_L28 PF00830.19 KKF96598.1 - 3.2e-16 59.3 0.7 5.2e-16 58.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal L28 family DUF3439 PF11921.8 KKF96598.1 - 0.14 12.1 2.0 0.24 11.4 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Trp_syntA PF00290.20 KKF96599.1 - 4.2e-88 294.6 0.0 8e-88 293.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KKF96599.1 - 1.1e-47 162.8 0.8 2.1e-47 161.9 0.8 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme JmjC PF02373.22 KKF96600.1 - 1.8e-08 34.8 0.1 4.5e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KKF96600.1 - 0.00018 21.7 7.1 0.00018 21.7 7.1 2.7 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KKF96600.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Ribosom_S12_S23 PF00164.25 KKF96601.1 - 2.5e-50 168.9 0.7 3.1e-50 168.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 KKF96601.1 - 0.0074 15.9 0.0 0.0081 15.8 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase HOOK PF05622.12 KKF96602.1 - 5.3e-13 48.0 50.8 5.3e-13 48.0 50.8 2.9 1 1 2 3 3 3 2 HOOK protein ADK PF00406.22 KKF96603.1 - 2e-58 196.8 0.0 2.5e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KKF96603.1 - 5.2e-23 82.0 0.2 1.4e-22 80.6 0.1 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 KKF96603.1 - 1.1e-17 63.7 0.0 3.8e-17 62.0 0.0 2.0 3 0 0 3 3 3 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KKF96603.1 - 0.00015 22.3 0.0 0.00062 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKF96603.1 - 0.0019 18.4 0.0 0.0035 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KKF96603.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MitMem_reg PF13012.6 KKF96604.1 - 1.7e-37 128.2 0.2 8.1e-37 126.1 0.2 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KKF96604.1 - 1.6e-27 95.8 0.0 5.4e-27 94.1 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 KKF96604.1 - 0.023 14.4 1.8 0.037 13.7 1.8 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain Coprogen_oxidas PF01218.18 KKF96605.1 - 1.4e-142 473.7 0.0 1.6e-142 473.5 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.16 KKF96606.1 - 1.9e-51 172.6 0.2 2.2e-51 172.4 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KKF96606.1 - 6.2e-07 29.7 0.0 7.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 HAD PF12710.7 KKF96610.1 - 8.2e-18 65.5 0.1 1.9e-17 64.3 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKF96610.1 - 2e-12 47.9 1.7 4.3e-12 46.8 1.7 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKF96610.1 - 7.3e-08 32.5 0.7 3.1e-07 30.4 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.12 KKF96610.1 - 0.008 15.7 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) HAD_2 PF13419.6 KKF96610.1 - 0.093 12.8 0.5 7.1 6.7 0.0 2.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 KKF96610.1 - 0.095 12.2 0.2 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase TIP39 PF14980.6 KKF96610.1 - 0.14 12.0 0.4 0.35 10.8 0.4 1.6 1 0 0 1 1 1 0 TIP39 peptide PAPS_reduct PF01507.19 KKF96611.1 - 5.6e-41 140.5 0.0 7.2e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF5363 PF17320.2 KKF96611.1 - 0.081 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5363) TYW3 PF02676.14 KKF96612.1 - 1.2e-71 240.5 0.0 1.9e-71 239.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF1690 PF07956.11 KKF96613.1 - 2.4e-40 138.2 0.8 2.8e-40 138.0 0.8 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Choline_kinase PF01633.20 KKF96613.1 - 0.092 12.3 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ferric_reduct PF01794.19 KKF96614.1 - 8.6e-23 80.8 8.9 8.6e-23 80.8 8.9 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KKF96614.1 - 1.5e-16 60.9 0.0 6.2e-14 52.4 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKF96614.1 - 4.7e-09 36.3 0.0 1.1e-07 31.8 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain DUF2101 PF09874.9 KKF96614.1 - 0.099 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) HMGL-like PF00682.19 KKF96615.1 - 6.3e-78 262.0 0.0 7.9e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KKF96615.1 - 1.8e-26 92.6 0.0 1.2e-25 90.0 0.0 2.2 2 1 0 2 2 2 1 LeuA allosteric (dimerisation) domain ETF_alpha PF00766.19 KKF96615.1 - 0.15 12.1 0.2 0.34 11.0 0.2 1.6 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain Sigma_reg_N PF13800.6 KKF96615.1 - 0.17 12.2 0.1 0.35 11.2 0.1 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal HEAT_EZ PF13513.6 KKF96616.1 - 4.3e-12 46.3 15.5 2.4e-07 31.1 0.0 8.5 7 2 2 9 9 9 1 HEAT-like repeat IBN_N PF03810.19 KKF96616.1 - 1.9e-09 37.3 0.1 1.9e-09 37.3 0.1 4.0 5 0 0 5 5 5 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KKF96616.1 - 9.4e-09 35.5 12.9 0.11 12.9 0.1 7.4 3 2 5 8 8 8 3 HEAT repeats HEAT PF02985.22 KKF96616.1 - 1.6e-08 34.1 29.6 0.042 14.1 0.0 9.5 13 1 0 13 13 9 3 HEAT repeat CLASP_N PF12348.8 KKF96616.1 - 0.00016 21.3 5.7 1.7 8.1 0.1 5.5 2 1 3 5 5 5 2 CLASP N terminal Arm PF00514.23 KKF96616.1 - 0.0015 18.5 4.6 21 5.3 0.0 6.2 6 1 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KKF96616.1 - 0.012 15.7 2.0 0.033 14.2 0.2 2.6 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 UTP15_C PF09384.10 KKF96616.1 - 0.036 13.7 0.1 0.6 9.8 0.1 3.0 1 1 0 1 1 1 0 UTP15 C terminal DUF3160 PF11369.8 KKF96616.1 - 0.043 12.3 0.2 8.9 4.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3160) NUC173 PF08161.12 KKF96616.1 - 0.2 11.3 1.4 68 3.0 0.0 4.8 6 0 0 6 6 6 0 NUC173 domain TetR_C_33 PF13305.6 KKF96616.1 - 0.85 10.4 2.8 21 5.9 0.0 4.2 4 1 0 4 4 3 0 Tetracyclin repressor-like, C-terminal domain eIF3g PF12353.8 KKF96617.1 - 4.7e-43 146.5 1.6 9e-43 145.6 1.5 1.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KKF96617.1 - 1.1e-15 57.2 0.0 2.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KKF96617.1 - 0.12 12.7 0.2 0.26 11.6 0.2 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Aldolase_II PF00596.21 KKF96620.1 - 4.9e-49 166.8 1.5 7.3e-49 166.2 1.5 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DAO PF01266.24 KKF96621.1 - 3.9e-57 194.4 7.5 4.4e-57 194.2 7.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKF96621.1 - 3.2e-06 27.3 0.1 1.2e-05 25.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 KKF96621.1 - 0.0023 16.6 0.2 0.029 12.9 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 KKF96621.1 - 0.0094 15.2 0.0 0.027 13.7 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KKF96621.1 - 0.031 13.4 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KKF96621.1 - 0.072 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding HSP70 PF00012.20 KKF96622.1 - 7.8e-269 892.9 15.6 9e-269 892.7 15.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKF96622.1 - 1.2e-14 53.9 4.3 2.3e-13 49.7 1.2 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KKF96622.1 - 0.0002 21.1 0.0 0.00057 19.7 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Raco_middle PF17651.1 KKF96622.1 - 0.14 11.8 0.2 6.4 6.4 0.0 2.6 2 0 0 2 2 2 0 RACo middle region Big_3_4 PF13754.6 KKF96622.1 - 0.16 11.7 0.0 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function Med9 PF07544.13 KKF96622.1 - 0.45 10.6 4.8 6.5 6.9 0.3 3.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SRP68 PF16969.5 KKF96623.1 - 1.4e-175 585.5 0.9 1.6e-175 585.3 0.9 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PPR_2 PF13041.6 KKF96624.1 - 4.7e-08 33.1 5.5 0.04 14.1 0.1 5.8 5 1 1 6 6 6 3 PPR repeat family PPR PF01535.20 KKF96624.1 - 6.9e-06 26.0 7.4 0.32 11.4 0.1 7.1 7 0 0 7 7 7 1 PPR repeat PPR_3 PF13812.6 KKF96624.1 - 0.043 13.9 0.1 45 4.2 0.0 3.9 3 0 0 3 3 3 0 Pentatricopeptide repeat domain DUF3361 PF11841.8 KKF96624.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Chromosome_seg PF13889.6 KKF96625.1 - 3.8e-21 75.0 0.3 7.6e-21 74.0 0.3 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 KKF96625.1 - 0.0034 17.9 0.0 0.0076 16.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) CDC45 PF02724.14 KKF96626.1 - 0.96 7.7 16.6 1.8 6.8 16.6 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF4336 PF14234.6 KKF96627.1 - 2.4e-17 63.1 0.0 1e-08 34.7 0.0 3.0 2 1 1 3 3 3 3 Domain of unknown function (DUF4336) Peptidase_S8 PF00082.22 KKF96629.1 - 2.9e-36 125.3 9.9 5e-36 124.5 9.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KKF96629.1 - 2.8e-20 72.7 0.1 6.3e-20 71.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.18 KKF96630.1 - 1.8e-117 391.6 0.1 2.7e-116 387.8 0.0 2.3 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 KKF96630.1 - 5e-09 36.2 0.0 1.4e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 KKF96630.1 - 0.0031 16.8 0.4 1.4 8.1 0.0 3.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4704) DUF4800 PF16057.5 KKF96630.1 - 0.048 12.9 0.8 0.23 10.7 0.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4800) HPS3_N PF14761.6 KKF96630.1 - 0.19 11.2 0.0 0.44 10.0 0.0 1.5 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 DDOST_48kD PF03345.14 KKF96631.1 - 2.5e-157 524.0 0.0 3.1e-157 523.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Isy1 PF06246.12 KKF96632.1 - 1.1e-85 287.3 0.2 1.3e-85 287.0 0.2 1.1 1 0 0 1 1 1 1 Isy1-like splicing family SLC35F PF06027.12 KKF96633.1 - 7.8e-99 331.0 24.0 9.5e-99 330.7 24.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KKF96633.1 - 3.2e-09 36.2 6.4 3.2e-09 36.2 6.4 1.6 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KKF96633.1 - 1e-08 35.5 35.8 0.00016 21.8 14.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family Ninjurin PF04923.12 KKF96633.1 - 0.016 15.2 1.0 0.29 11.1 0.0 2.9 2 1 0 2 2 2 0 Ninjurin AhpC-TSA_2 PF13911.6 KKF96635.1 - 0.016 15.3 0.0 0.025 14.7 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme YjeF_N PF03853.15 KKF96636.1 - 1.2e-14 54.5 0.1 3.5e-14 53.0 0.0 1.5 1 1 1 2 2 2 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.19 KKF96637.1 - 1.6e-25 88.9 0.1 2.5e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.18 KKF96638.1 - 4.4e-46 157.4 1.0 7e-46 156.7 1.0 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bys1 PF04681.12 KKF96638.1 - 0.11 12.4 0.0 0.61 10.0 0.0 2.2 2 1 1 3 3 3 0 Blastomyces yeast-phase-specific protein Dynactin_p22 PF07426.11 KKF96639.1 - 0.0022 17.9 0.7 0.014 15.2 0.1 2.1 1 1 1 2 2 2 1 Dynactin subunit p22 FAD-SLDH PF12318.8 KKF96639.1 - 0.01 15.9 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase SH3_1 PF00018.28 KKF96640.1 - 4.5e-09 35.8 0.1 8.7e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKF96640.1 - 4.1e-06 26.4 0.0 8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KKF96640.1 - 8.2e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DASH_Spc19 PF08287.11 KKF96641.1 - 1.8e-50 170.9 0.8 2.8e-50 170.3 0.8 1.2 1 0 0 1 1 1 1 Spc19 DUF4398 PF14346.6 KKF96641.1 - 2 9.1 13.2 0.39 11.4 2.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) AAA PF00004.29 KKF96642.1 - 2.6e-13 50.5 0.0 5.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKF96642.1 - 0.00082 19.8 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKF96642.1 - 0.0019 18.5 0.0 0.0059 16.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KKF96642.1 - 0.028 14.4 0.0 0.076 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KKF96642.1 - 0.047 13.4 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KKF96642.1 - 0.077 12.3 0.2 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin RuvB_N PF05496.12 KKF96642.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Apolipoprotein PF01442.18 KKF96643.1 - 0.00012 22.0 2.9 0.00014 21.8 2.9 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KKF96643.1 - 0.017 15.2 7.2 0.072 13.2 7.2 1.8 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Fzo_mitofusin PF04799.13 KKF96643.1 - 0.039 13.5 1.0 0.1 12.1 0.2 1.8 1 1 1 2 2 2 0 fzo-like conserved region YtxH PF12732.7 KKF96643.1 - 0.043 14.3 14.9 79 3.9 14.9 2.2 1 1 0 1 1 1 0 YtxH-like protein DDHD PF02862.17 KKF96643.1 - 0.082 13.1 1.4 0.091 12.9 1.4 1.1 1 0 0 1 1 1 0 DDHD domain CsbD PF05532.12 KKF96643.1 - 0.17 11.8 16.5 0.89 9.5 5.9 3.0 1 1 1 2 2 2 0 CsbD-like DUF883 PF05957.13 KKF96643.1 - 0.25 11.9 6.6 4.7 7.9 6.6 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ECH_1 PF00378.20 KKF96644.1 - 9.3e-41 139.8 0.0 2.9e-37 128.3 0.0 2.3 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKF96644.1 - 2.8e-26 92.8 0.0 2.8e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_M43 PF05572.13 KKF96645.1 - 6.4e-15 55.4 0.0 8.9e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KKF96645.1 - 2.6e-05 24.7 0.0 3.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KKF96645.1 - 0.00013 22.2 0.1 0.00014 22.0 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KKF96645.1 - 0.0046 16.6 0.7 0.0078 15.9 0.7 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KKF96645.1 - 0.0081 15.1 0.9 0.012 14.6 0.9 1.2 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 KKF96645.1 - 0.036 13.9 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 KKF96645.1 - 0.054 12.7 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Metallopep PF12044.8 KKF96645.1 - 0.14 10.7 0.2 0.16 10.5 0.2 1.1 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_2 PF13574.6 KKF96645.1 - 0.15 12.0 1.4 0.25 11.2 1.4 1.3 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 KKF96645.1 - 0.18 11.8 0.3 0.35 10.8 0.3 1.4 1 0 0 1 1 1 0 Peptidase family M54 HAD_SAK_1 PF10307.9 KKF96646.1 - 9.1e-23 81.1 0.0 1.3e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins W2 PF02020.18 KKF96647.1 - 4.4e-19 68.4 3.0 4.4e-19 68.4 3.0 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KKF96647.1 - 1.7e-06 27.5 11.0 0.00047 19.8 0.6 3.9 1 1 4 5 5 5 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KKF96647.1 - 2.2e-05 24.2 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KKF96647.1 - 0.00069 20.0 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KKF96647.1 - 0.0029 16.6 0.0 0.0059 15.6 0.0 1.5 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KKF96647.1 - 0.042 12.0 0.3 0.067 11.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KKF96647.1 - 2.2 8.1 6.6 2.5 7.9 0.3 3.1 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Response_reg PF00072.24 KKF96648.1 - 3.8e-24 85.0 0.0 3.8e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain Med15 PF09606.10 KKF96648.1 - 0.00024 20.0 29.7 0.00024 20.0 29.7 1.4 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Bactofilin PF04519.13 KKF96648.1 - 0.0052 17.1 1.0 0.0093 16.2 1.0 1.3 1 0 0 1 1 1 1 Polymer-forming cytoskeletal Spt20 PF12090.8 KKF96648.1 - 0.0055 16.4 16.3 0.0079 15.8 16.3 1.2 1 0 0 1 1 1 1 Spt20 family DUF4192 PF13830.6 KKF96648.1 - 0.11 12.5 10.8 0.16 12.0 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) RR_TM4-6 PF06459.12 KKF96648.1 - 0.27 11.0 3.8 0.42 10.4 3.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pinin_SDK_memA PF04696.13 KKF96648.1 - 0.32 11.1 10.2 0.53 10.4 10.2 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DDHD PF02862.17 KKF96648.1 - 0.41 10.8 5.0 0.59 10.3 5.0 1.2 1 0 0 1 1 1 0 DDHD domain RIFIN PF02009.16 KKF96648.1 - 0.52 10.1 8.3 0.7 9.7 8.3 1.1 1 0 0 1 1 1 0 Rifin CCDC53 PF10152.9 KKF96648.1 - 1.1 9.7 8.4 6.4 7.2 8.4 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TFIIA PF03153.13 KKF96648.1 - 1.2 9.0 25.6 1.8 8.5 25.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_III_AF PF09581.10 KKF96648.1 - 1.3 9.0 7.2 2.1 8.3 7.2 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) dCache_2 PF08269.11 KKF96648.1 - 6 5.9 7.1 9.6 5.3 7.1 1.2 1 0 0 1 1 1 0 Cache domain DNA_primase_S PF01896.19 KKF96649.1 - 2.2e-63 213.5 1.6 7.4e-63 211.8 0.2 2.1 2 0 0 2 2 2 1 DNA primase small subunit tRNA_m1G_MT PF01746.21 KKF96650.1 - 2.6e-25 89.3 0.2 3e-19 69.5 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase TP2 PF01254.18 KKF96650.1 - 2.4 8.8 7.9 4.9 7.8 7.9 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 MutS_V PF00488.21 KKF96651.1 - 3.9e-84 281.4 0.3 6.6e-84 280.6 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKF96651.1 - 2.2e-36 125.9 1.1 8.7e-36 123.9 1.0 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KKF96651.1 - 1.3e-22 80.5 5.6 8.3e-22 78.0 0.0 4.1 4 0 0 4 4 4 1 MutS domain II MutS_IV PF05190.18 KKF96651.1 - 1.9e-18 66.6 3.3 1e-17 64.3 2.1 2.7 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.20 KKF96651.1 - 5.7e-17 62.0 0.0 4.5e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 MutS domain I AAA_27 PF13514.6 KKF96651.1 - 0.062 12.9 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain MAP65_ASE1 PF03999.12 KKF96651.1 - 0.11 11.2 4.9 0.18 10.5 4.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF2089 PF09862.9 KKF96651.1 - 0.13 12.3 0.1 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2089) Tim17 PF02466.19 KKF96652.1 - 0.05 14.0 7.6 0.059 13.7 6.8 1.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family SpecificRecomb PF10136.9 KKF96652.1 - 0.22 9.8 0.1 0.84 7.9 0.0 1.7 2 0 0 2 2 2 0 Site-specific recombinase UCH PF00443.29 KKF96653.1 - 1.3e-22 80.6 0.0 1.8e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KKF96653.1 - 9.5e-09 35.1 1.6 0.00015 21.7 0.0 2.9 3 0 0 3 3 3 2 A repeated domain in UCH-protein 2-oxoacid_dh PF00198.23 KKF96654.1 - 4.4e-71 239.0 0.1 5.6e-71 238.7 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KKF96654.1 - 8e-20 70.5 1.4 1.7e-19 69.4 1.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KKF96654.1 - 1.7e-09 37.8 1.7 1.7e-09 37.8 1.7 2.4 2 0 0 2 2 2 1 e3 binding domain DUF3614 PF12267.8 KKF96654.1 - 0.045 14.2 1.5 0.13 12.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3614) Biotin_lipoyl_2 PF13533.6 KKF96654.1 - 0.11 12.3 0.1 0.43 10.4 0.1 2.0 1 1 1 2 2 2 0 Biotin-lipoyl like NACHT PF05729.12 KKF96655.1 - 3.6e-18 66.0 0.0 6.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Patatin PF01734.22 KKF96655.1 - 3e-05 24.3 0.5 7.2e-05 23.0 0.3 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase AAA_19 PF13245.6 KKF96655.1 - 0.0011 19.3 0.0 0.0028 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKF96655.1 - 0.0089 16.3 0.2 0.092 13.0 0.0 2.6 2 2 1 3 3 3 1 AAA domain KAP_NTPase PF07693.14 KKF96655.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain DUF2075 PF09848.9 KKF96655.1 - 0.024 13.9 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KKF96655.1 - 0.06 13.7 0.0 0.97 9.8 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain HTH_44 PF14641.6 KKF96655.1 - 0.11 12.9 0.2 0.4 11.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 Glyco_hydro_28 PF00295.17 KKF96657.1 - 6.1e-120 400.2 21.5 6.9e-120 400.0 21.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Med12 PF09497.10 KKF96658.1 - 1.4e-27 95.7 0.2 3.4e-27 94.5 0.2 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 MMR1 PF08505.10 KKF96658.1 - 0.52 10.6 16.3 1.2 9.3 16.3 1.6 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein EPL1 PF10513.9 KKF96658.1 - 1.2 9.5 10.7 2.8 8.3 10.7 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like Zip PF02535.22 KKF96658.1 - 4.6 6.4 13.7 7.1 5.7 13.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter STAC2_u1 PF16664.5 KKF96658.1 - 4.9 7.6 14.0 12 6.4 14.0 1.6 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Endostatin PF06482.11 KKF96658.1 - 5.3 6.4 16.6 10 5.4 16.6 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Macoilin PF09726.9 KKF96658.1 - 8.4 4.8 12.8 14 4.1 12.8 1.3 1 0 0 1 1 1 0 Macoilin family RhoGAP PF00620.27 KKF96659.1 - 1.6e-47 161.1 1.6 3.1e-47 160.2 0.1 2.2 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.23 KKF96659.1 - 1.4e-10 41.3 0.4 1.1e-09 38.4 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Filament PF00038.21 KKF96659.1 - 0.00087 19.0 6.5 0.0015 18.2 6.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein OmpH PF03938.14 KKF96659.1 - 0.45 10.8 7.4 0.83 10.0 7.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Uso1_p115_C PF04871.13 KKF96659.1 - 2.2 8.6 7.6 4.5 7.7 7.6 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CMS1 PF14617.6 KKF96660.1 - 7.1e-75 251.6 0.7 8.4e-75 251.4 0.7 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KKF96660.1 - 3.2e-06 27.0 0.0 4.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase KH_6 PF15985.5 KKF96661.1 - 1.6e-15 57.2 0.0 3.3e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KKF96661.1 - 6.1e-14 51.7 0.8 1.3e-13 50.7 0.8 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain HSP70 PF00012.20 KKF96662.1 - 6.4e-78 262.4 3.4 9.3e-78 261.9 3.4 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKF96662.1 - 3e-05 23.0 0.1 4.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein NT-C2 PF10358.9 KKF96663.1 - 6.3e-19 68.1 0.0 1.9e-18 66.6 0.0 1.7 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Optomotor-blind PF11078.8 KKF96663.1 - 0.036 14.6 2.4 0.1 13.2 2.4 1.7 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region WH1 PF00568.23 KKF96666.1 - 8.4e-30 103.0 0.2 1.3e-29 102.4 0.2 1.3 1 0 0 1 1 1 1 WH1 domain DCP1 PF06058.13 KKF96666.1 - 0.00012 22.0 0.2 0.0002 21.3 0.2 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family eIF-1a PF01176.19 KKF96667.1 - 2.6e-21 75.2 0.0 3.8e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pirin PF02678.16 KKF96669.1 - 4.5e-26 90.9 0.7 1.2e-25 89.6 0.7 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KKF96669.1 - 0.0056 16.4 1.7 0.19 11.5 0.4 3.0 2 1 0 2 2 2 1 Cupin domain Oxysterol_BP PF01237.18 KKF96670.1 - 1.6e-132 441.9 0.0 1.6e-132 441.9 0.0 2.5 3 0 0 3 3 3 1 Oxysterol-binding protein Ank PF00023.30 KKF96670.1 - 3.1e-15 55.8 0.3 0.00021 21.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KKF96670.1 - 4.7e-15 55.5 0.0 5.9e-09 36.0 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKF96670.1 - 1.3e-13 51.3 0.0 5.2e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKF96670.1 - 1.4e-13 51.1 0.1 2.1e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKF96670.1 - 1.5e-11 43.5 0.1 0.004 17.5 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.29 KKF96670.1 - 1.9e-10 41.2 0.4 4.4e-10 40.0 0.4 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KKF96670.1 - 4.5e-06 26.9 0.5 1.1e-05 25.7 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain GPS2_interact PF15784.5 KKF96670.1 - 0.026 15.0 2.6 0.076 13.5 2.6 1.8 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain LLC1 PF14945.6 KKF96670.1 - 0.1 13.2 0.9 0.37 11.4 0.9 1.9 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Zn_clus PF00172.18 KKF96671.1 - 0.0013 18.8 13.9 0.0027 17.8 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KKF96671.1 - 0.044 13.6 0.5 0.1 12.6 0.5 1.6 1 0 0 1 1 1 0 AT hook motif CYYR1 PF10873.8 KKF96671.1 - 5.2 7.5 8.0 1.4 9.3 1.4 2.3 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Annexin PF00191.20 KKF96673.1 - 0.0034 17.4 2.5 0.0047 17.0 0.1 2.4 3 1 0 3 3 3 1 Annexin Peptidase_S28 PF05577.12 KKF96674.1 - 1.4e-48 165.8 1.1 2.6e-47 161.6 1.1 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Sulfate_transp PF00916.20 KKF96675.1 - 2.7e-116 388.5 16.2 3.4e-116 388.1 16.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KKF96675.1 - 8.8e-11 41.5 0.0 2.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KKF96675.1 - 1.7e-05 25.1 16.8 3.7e-05 24.1 3.3 3.6 3 2 1 4 4 4 2 Molybdate transporter of MFS superfamily YdjM PF04307.14 KKF96675.1 - 0.025 13.9 0.2 0.11 11.8 0.2 2.2 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase DUF4271 PF14093.6 KKF96675.1 - 0.56 10.1 14.1 1.3 8.9 2.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) G-patch PF01585.23 KKF96676.1 - 7.8e-13 48.1 1.0 1.3e-12 47.4 1.0 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KKF96676.1 - 2.6e-06 27.4 1.5 5.9e-06 26.3 1.2 1.9 1 1 0 1 1 1 1 G-patch domain RED_N PF07808.13 KKF96676.1 - 0.0013 18.4 3.0 0.0013 18.4 3.0 1.4 2 0 0 2 2 2 1 RED-like protein N-terminal region MoaE PF02391.17 KKF96677.1 - 8.4e-41 138.8 0.0 1.2e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 MoaE protein Ferric_reduct PF01794.19 KKF96678.1 - 1.7e-17 63.7 5.5 1.7e-17 63.7 5.5 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_4 PF01565.23 KKF96678.1 - 6.7e-17 61.5 0.1 1.2e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.12 KKF96678.1 - 2.2e-11 44.1 0.0 3.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKF96678.1 - 2.8e-11 43.5 0.0 6.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KKF96678.1 - 0.0032 18.1 0.0 0.0074 16.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain RNase_PH PF01138.21 KKF96679.1 - 1.7e-17 64.2 0.0 6.4e-17 62.3 0.0 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKF96679.1 - 1.7e-05 24.7 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 GDI PF00996.18 KKF96680.1 - 3.1e-30 105.1 0.0 2e-29 102.4 0.0 1.9 1 1 0 1 1 1 1 GDP dissociation inhibitor AMP-binding PF00501.28 KKF96681.1 - 1.2e-10 40.6 0.7 1.7e-10 40.1 0.7 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKF96681.1 - 7e-09 36.5 0.1 1.6e-08 35.4 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Rad21_Rec8_N PF04825.13 KKF96681.1 - 1.7e-07 31.4 0.0 4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein MRP_L53 PF10780.9 KKF96681.1 - 0.011 15.8 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 Rad21_Rec8 PF04824.16 KKF96681.1 - 0.044 13.1 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Conserved region of Rad21 / Rec8 like protein Response_reg PF00072.24 KKF96682.1 - 9.7e-22 77.3 0.1 2.1e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KKF96682.1 - 2.9e-20 72.1 0.4 2.9e-20 72.1 0.4 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KKF96682.1 - 7.8e-06 26.2 0.0 3.7e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 KKF96682.1 - 0.017 15.8 0.0 0.052 14.2 0.0 1.8 2 0 0 2 2 2 0 GAF domain DUF2514 PF10721.9 KKF96682.1 - 0.025 14.6 7.8 0.043 13.8 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) ABM PF03992.16 KKF96683.1 - 0.0059 16.7 0.0 0.0077 16.3 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Post_transc_reg PF13797.6 KKF96683.1 - 0.015 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Post-transcriptional regulator VirC1 PF07015.11 KKF96683.1 - 0.069 12.4 0.1 1.1 8.5 0.1 1.9 1 1 1 2 2 2 0 VirC1 protein HEAT_EZ PF13513.6 KKF96684.1 - 0.0032 17.9 2.2 3.5 8.3 0.0 3.4 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KKF96684.1 - 0.12 12.7 0.3 0.44 10.9 0.1 2.2 2 0 0 2 2 2 0 HEAT repeat SNF2_N PF00176.23 KKF96685.1 - 4.9e-73 245.9 0.0 7.3e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKF96685.1 - 2.7e-12 47.0 0.0 1.2e-11 45.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKF96685.1 - 2.7e-05 24.0 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 KKF96685.1 - 0.0015 18.4 3.1 0.0034 17.3 3.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 KKF96685.1 - 0.0018 18.3 0.0 0.013 15.6 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HIRAN PF08797.11 KKF96685.1 - 0.0043 17.0 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 HIRAN domain zf-RING_UBOX PF13445.6 KKF96685.1 - 0.024 14.7 0.4 0.063 13.3 0.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KKF96685.1 - 0.12 12.2 7.5 0.017 15.0 2.2 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKF96685.1 - 0.13 12.2 3.7 0.37 10.7 3.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 GCP_N_terminal PF17681.1 KKF96686.1 - 8.2e-63 212.8 0.0 1.8e-62 211.7 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KKF96686.1 - 2e-57 195.0 0.4 2e-57 195.0 0.4 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Proteasome PF00227.26 KKF96687.1 - 9.3e-58 194.9 0.0 1.2e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKF96687.1 - 1.6e-12 46.8 0.0 3.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fungal_trans_2 PF11951.8 KKF96688.1 - 2.2e-12 46.5 1.1 5.2e-10 38.7 0.1 3.7 3 1 0 3 3 3 2 Fungal specific transcription factor domain EPL1 PF10513.9 KKF96688.1 - 2.3 8.6 7.9 1.7 9.0 4.7 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Methyltransf_8 PF05148.15 KKF96689.1 - 4.5e-55 186.9 0.0 4e-53 180.5 0.0 3.2 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KKF96689.1 - 4.6e-05 24.0 0.1 0.0003 21.4 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF96689.1 - 0.0031 18.2 0.1 0.42 11.3 0.1 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KKF96689.1 - 0.0086 16.1 2.6 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain UPF0560 PF10577.9 KKF96689.1 - 0.18 10.3 7.6 0.27 9.7 7.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CPSF100_C PF13299.6 KKF96689.1 - 0.46 10.6 15.2 1.5 9.0 11.7 3.0 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Asp_protease PF09668.10 KKF96690.1 - 4.2e-58 194.5 0.6 6.1e-58 194.0 0.6 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KKF96690.1 - 5.4e-22 78.2 0.1 1.3e-21 76.9 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KKF96690.1 - 1.7e-11 44.6 0.1 4.7e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 KKF96690.1 - 3.8e-09 36.3 0.2 3e-08 33.4 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 KKF96690.1 - 1.3e-06 28.1 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 KKF96690.1 - 5.9e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.8 KKF96690.1 - 9.1e-05 22.9 0.0 0.00017 22.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 RVP PF00077.20 KKF96690.1 - 0.0002 21.6 0.0 0.00045 20.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 KKF96690.1 - 0.00029 20.6 0.1 0.00055 19.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like NUDE_C PF04880.13 KKF96690.1 - 0.65 10.5 3.5 80 3.6 3.8 3.1 3 0 0 3 3 3 0 NUDE protein, C-terminal conserved region Acetyltransf_10 PF13673.7 KKF96691.1 - 2e-05 24.5 0.0 2.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKF96691.1 - 5.9e-05 23.3 0.0 8.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKF96691.1 - 0.00096 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pribosyltran PF00156.27 KKF96692.1 - 5.1e-16 58.6 0.2 7.6e-16 58.0 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NOG1_N PF17835.1 KKF96693.1 - 1.3e-47 161.7 0.0 1.3e-47 161.7 0.0 2.3 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KKF96693.1 - 2.4e-27 94.7 0.8 4.7e-27 93.7 0.8 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KKF96693.1 - 3.9e-25 87.4 0.3 8.5e-25 86.3 0.3 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KKF96693.1 - 1.8e-14 53.8 0.0 3.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKF96693.1 - 1.5e-07 31.1 0.0 3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B PPV_E1_C PF00519.17 KKF96693.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Dynamin_N PF00350.23 KKF96693.1 - 0.19 11.7 4.0 4.2 7.4 0.0 3.3 2 1 1 3 3 3 0 Dynamin family GDI PF00996.18 KKF96694.1 - 4.2e-188 625.3 0.0 5.3e-188 624.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor MRP-L47 PF06984.13 KKF96695.1 - 1.5e-20 73.1 0.0 2.3e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) zf-H2C2_2 PF13465.6 KKF96696.1 - 6.7e-06 26.3 1.1 6.7e-06 26.3 1.1 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KKF96696.1 - 0.00023 21.4 4.1 0.0004 20.6 4.1 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KKF96696.1 - 0.00026 21.5 15.1 0.023 15.5 5.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKF96696.1 - 0.033 14.5 3.1 3.3 8.1 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KKF96696.1 - 0.067 13.7 14.6 0.14 12.7 7.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4148 PF13663.6 KKF96696.1 - 2.7 8.2 9.6 0.65 10.2 0.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Lactamase_B_2 PF12706.7 KKF96697.1 - 2.7e-31 108.7 0.1 1.8e-29 102.7 0.1 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKF96697.1 - 1.7e-09 37.8 0.0 2.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKF96697.1 - 0.0053 16.8 3.8 0.066 13.2 2.0 2.9 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Ysc84 PF04366.12 KKF96698.1 - 1.5e-27 95.9 0.0 2.6e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Cwf_Cwc_15 PF04889.12 KKF96698.1 - 0.85 9.3 6.6 1.6 8.4 6.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Actin PF00022.19 KKF96699.1 - 7.5e-18 64.3 0.0 1.2e-14 53.7 0.0 3.1 3 0 0 3 3 3 2 Actin MreB_Mbl PF06723.13 KKF96699.1 - 5e-05 22.3 0.0 0.0041 16.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KKF96699.1 - 0.09 13.2 0.2 0.18 12.3 0.2 1.8 1 1 0 1 1 1 0 Cell division protein FtsA FA_desaturase PF00487.24 KKF96700.1 - 3.2e-16 60.0 13.7 3.2e-16 60.0 13.7 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KKF96700.1 - 3.2e-16 59.2 0.0 8.4e-16 57.9 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 KKF96701.1 - 4.3e-10 39.4 0.1 2.5e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96701.1 - 1.1e-07 31.4 0.0 2e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase WaaY PF06176.11 KKF96701.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Lon_C PF05362.13 KKF96702.1 - 2.5e-65 219.9 0.0 4.8e-65 219.0 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KKF96702.1 - 7.4e-32 110.9 0.0 1.9e-31 109.6 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KKF96702.1 - 2.2e-22 79.9 0.0 2.3e-21 76.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKF96702.1 - 6.6e-07 29.4 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KKF96702.1 - 1.5e-06 28.5 0.0 7.5e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 KKF96702.1 - 3.5e-06 26.9 0.0 9.5e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 KKF96702.1 - 2.7e-05 24.5 0.3 0.00039 20.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 KKF96702.1 - 6.9e-05 21.9 0.0 0.00015 20.8 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KKF96702.1 - 8e-05 22.4 0.1 0.00076 19.3 0.0 2.7 5 0 0 5 5 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKF96702.1 - 0.00041 20.8 1.0 0.0029 18.0 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KKF96702.1 - 0.0027 17.7 0.0 0.052 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.9 KKF96702.1 - 0.0068 16.4 2.9 0.012 15.7 0.1 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_30 PF13604.6 KKF96702.1 - 0.009 15.7 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKF96702.1 - 0.025 15.1 0.4 0.083 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KKF96702.1 - 0.038 13.9 0.3 1.7 8.5 0.0 3.0 2 1 1 3 3 3 0 NTPase RNA_helicase PF00910.22 KKF96702.1 - 0.064 13.6 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KKF96702.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KKF96702.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 KKF96702.1 - 0.11 13.0 1.2 1.1 9.8 0.1 2.7 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 KKF96702.1 - 0.12 11.9 0.6 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KKF96702.1 - 5.1 7.6 7.3 6.2 7.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain Jak1_Phl PF17887.1 KKF96703.1 - 1.3 8.9 7.2 0.47 10.4 2.2 2.0 1 1 1 2 2 2 0 Jak1 pleckstrin homology-like domain GlyL_C PF12524.8 KKF96703.1 - 6.4 7.0 7.5 3.2 8.0 3.1 2.5 1 1 1 2 2 2 0 dsDNA virus glycoprotein L C terminal DUF2034 PF10356.9 KKF96704.1 - 2.6e-27 95.5 0.0 2e-13 50.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KKF96704.1 - 1.1e-08 35.1 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.8 KKF96705.1 - 4.8e-31 108.0 16.8 1.7e-27 96.4 7.2 2.0 1 1 1 2 2 2 2 Subunit 21 of Mediator complex CtIP_N PF10482.9 KKF96705.1 - 0.0029 17.6 1.1 0.0058 16.7 0.5 1.7 1 1 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain Med9 PF07544.13 KKF96705.1 - 0.008 16.3 0.2 0.008 16.3 0.2 2.5 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 FAM76 PF16046.5 KKF96705.1 - 0.022 14.1 0.7 0.025 14.0 0.7 1.2 1 0 0 1 1 1 0 FAM76 protein Herpes_UL6 PF01763.16 KKF96705.1 - 0.03 12.8 1.5 0.035 12.6 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like APG6_N PF17675.1 KKF96705.1 - 0.053 14.1 9.4 0.091 13.3 9.4 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Spore_III_AB PF09548.10 KKF96705.1 - 0.092 12.9 1.9 0.11 12.6 1.9 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF3090 PF11290.8 KKF96705.1 - 0.16 11.8 2.9 0.18 11.6 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) HAUS-augmin3 PF14932.6 KKF96705.1 - 0.18 11.3 4.7 0.23 11.0 4.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 GIT_CC PF16559.5 KKF96705.1 - 0.22 11.4 0.5 0.22 11.4 0.5 2.6 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor PspA_IM30 PF04012.12 KKF96705.1 - 0.23 11.0 8.8 0.67 9.5 8.8 1.7 1 1 0 1 1 1 0 PspA/IM30 family Spc7 PF08317.11 KKF96705.1 - 0.36 9.7 5.8 0.4 9.5 5.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Pup PF05639.11 KKF96705.1 - 0.92 10.5 10.7 2.5 9.1 2.2 2.5 2 1 0 2 2 2 0 Pup-like protein YabA PF06156.13 KKF96705.1 - 3.6 8.3 5.3 10 6.9 1.2 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF4140 PF13600.6 KKF96705.1 - 5.3 7.6 12.3 11 6.5 6.5 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 KKF96705.1 - 9.9 6.5 9.6 15 5.9 0.8 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HAD_2 PF13419.6 KKF96706.1 - 1.9e-10 41.1 0.0 2.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKF96706.1 - 6.3e-10 39.7 0.0 3.7e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KKF96706.1 - 0.018 14.9 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Acid Phosphatase DUF4437 PF14499.6 KKF96706.1 - 0.064 12.4 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) HAD PF12710.7 KKF96706.1 - 0.098 13.0 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase_fungal PF17667.1 KKF96707.1 - 1.2e-51 175.8 0.0 2.2e-51 174.9 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KKF96707.1 - 1.1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96707.1 - 0.046 13.0 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 KKF96707.1 - 0.048 13.6 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KKF96707.1 - 0.091 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KH_1 PF00013.29 KKF96709.1 - 1.7e-24 85.4 3.9 2.5e-05 24.0 0.1 6.9 7 0 0 7 7 7 6 KH domain BET PF17035.5 KKF96709.1 - 0.08 13.1 0.6 1.7 8.8 0.1 2.6 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation ResIII PF04851.15 KKF96710.1 - 2e-21 76.7 0.2 2.8e-20 73.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKF96710.1 - 3.7e-16 59.4 0.1 1.4e-14 54.4 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKF96710.1 - 3e-14 53.2 0.0 1.1e-12 48.1 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KKF96710.1 - 4.5e-05 23.2 0.0 7.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KKF96710.1 - 0.0048 16.2 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KKF96710.1 - 0.036 14.4 1.1 0.065 13.6 0.3 1.8 2 0 0 2 2 2 0 AAA domain Eaf7 PF07904.13 KKF96712.1 - 7.9e-24 84.1 0.2 7.9e-24 84.1 0.2 1.8 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 CDC27 PF09507.10 KKF96712.1 - 0.036 13.5 17.2 0.049 13.0 17.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GCP_C_terminal PF04130.13 KKF96713.1 - 1.2e-69 235.1 1.7 1.4e-69 234.9 0.2 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KKF96713.1 - 1.9e-29 103.3 0.7 3.5e-29 102.4 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF2828 PF11443.8 KKF96714.1 - 2.2e-139 465.5 0.0 1.1e-138 463.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF2828) His_Phos_1 PF00300.22 KKF96715.1 - 0.0014 18.4 0.2 0.027 14.1 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) PEX11 PF05648.14 KKF96716.1 - 0.0086 15.6 4.3 0.33 10.4 0.1 3.1 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Ribosomal_S11 PF00411.19 KKF96717.1 - 5.4e-46 155.5 1.5 6.7e-46 155.2 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 KKF96717.1 - 0.06 12.7 0.1 0.074 12.3 0.1 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme CBM_25 PF03423.13 KKF96717.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Ribosomal_L30_N PF08079.12 KKF96718.1 - 1.2e-24 86.3 16.1 2.2e-24 85.5 16.1 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KKF96718.1 - 3.2e-17 62.1 2.2 3.2e-17 62.1 2.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Fe-S_biosyn PF01521.20 KKF96719.1 - 9.4e-08 32.2 0.0 1.4e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis eIF-3c_N PF05470.12 KKF96720.1 - 2e-181 604.4 5.0 2e-181 604.4 5.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KKF96720.1 - 7.7e-12 45.7 0.3 2.4e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 PCI domain RasGAP_C PF03836.15 KKF96720.1 - 0.13 12.4 1.9 0.22 11.7 0.3 2.2 2 0 0 2 2 2 0 RasGAP C-terminus CDC45 PF02724.14 KKF96720.1 - 0.77 8.0 16.7 1.2 7.3 16.7 1.3 1 0 0 1 1 1 0 CDC45-like protein SEEEED PF14797.6 KKF96720.1 - 0.8 9.9 39.0 0.099 12.8 31.1 2.3 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex SNF2_N PF00176.23 KKF96721.1 - 5.2e-54 183.3 0.0 7.7e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKF96721.1 - 9.2e-18 64.6 0.0 3e-17 63.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XhlA PF10779.9 KKF96721.1 - 6.9 7.0 6.0 17 5.7 0.6 2.9 2 0 0 2 2 2 0 Haemolysin XhlA Phage_B PF02304.15 KKF96721.1 - 7 7.1 8.3 1 9.7 1.5 3.1 3 1 0 3 3 3 0 Scaffold protein B Zip PF02535.22 KKF96722.1 - 3.6e-32 111.9 18.7 7.7e-23 81.2 5.3 3.0 2 1 1 3 3 3 2 ZIP Zinc transporter NST1 PF13945.6 KKF96723.1 - 3.8e-50 170.7 12.8 3.8e-50 170.7 12.8 4.2 2 2 2 4 4 4 1 Salt tolerance down-regulator Selenoprotein_S PF06936.11 KKF96724.1 - 0.11 12.3 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) Pre-PUA PF17832.1 KKF96725.1 - 1.4e-18 67.4 0.0 2.4e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KKF96725.1 - 7.3e-13 48.3 0.0 2.3e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 PUA domain DUF4690 PF15756.5 KKF96727.1 - 0.0016 19.0 0.1 0.036 14.7 0.0 2.4 2 1 1 3 3 3 1 Small Novel Rich in Cartilage RCR PF12273.8 KKF96727.1 - 0.039 14.6 2.5 0.15 12.8 2.5 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red VSP PF03302.13 KKF96727.1 - 0.047 12.6 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein CYYR1 PF10873.8 KKF96727.1 - 0.061 13.8 0.8 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 TMEM51 PF15345.6 KKF96727.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 TFIIF_alpha PF05793.12 KKF96727.1 - 0.18 10.4 1.1 0.21 10.1 1.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Syndecan PF01034.20 KKF96727.1 - 0.22 11.5 0.2 0.35 10.8 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 KKF96727.1 - 7 6.5 4.8 1.1 9.2 0.1 2.0 2 1 1 3 3 3 0 TMEM154 protein family VPS9 PF02204.18 KKF96728.1 - 4.6e-19 68.6 0.1 1.2e-18 67.2 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 KKF96728.1 - 8.9e-15 55.1 1.0 5.8e-06 26.8 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKF96728.1 - 1.1e-12 47.9 4.1 3.7e-09 36.7 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKF96728.1 - 4.6e-07 30.3 0.3 1.2 9.8 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKF96728.1 - 1e-06 28.6 0.0 1.8 9.4 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat PX PF00787.24 KKF96728.1 - 0.0005 20.0 0.8 0.0012 18.9 0.1 2.0 2 0 0 2 2 2 1 PX domain Ank PF00023.30 KKF96728.1 - 0.0013 19.1 0.7 7.3 7.2 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat YchF-GTPase_C PF06071.13 KKF96730.1 - 4.8e-35 119.6 0.1 1.2e-34 118.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KKF96730.1 - 4e-17 62.3 0.0 1.5e-16 60.4 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKF96730.1 - 0.00011 21.7 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KKF96730.1 - 0.0017 18.4 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain AAA_18 PF13238.6 KKF96730.1 - 0.04 14.5 0.7 1.6 9.3 0.6 3.1 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KKF96730.1 - 0.061 13.4 0.2 5.7 7.0 0.0 2.9 2 1 1 3 3 3 0 Dynamin family AAA_14 PF13173.6 KKF96730.1 - 0.071 13.1 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Peptidase_C97 PF05903.14 KKF96731.1 - 1.2e-32 112.8 0.0 1.5e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KKF96731.1 - 0.008 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Ribosomal_S11 PF00411.19 KKF96732.1 - 2.7e-10 40.6 0.0 4.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.15 KKF96733.1 - 1.5e-34 119.2 0.1 6.4e-34 117.2 0.0 2.1 2 0 0 2 2 2 1 Tim44-like domain Med7 PF05983.11 KKF96733.1 - 0.42 10.7 5.2 0.82 9.7 5.2 1.5 1 0 0 1 1 1 0 MED7 protein Striatin PF08232.12 KKF96733.1 - 2.5 8.7 11.7 0.21 12.1 6.4 1.8 2 0 0 2 2 2 0 Striatin family TRAP_alpha PF03896.16 KKF96733.1 - 10 5.3 7.8 2.1 7.5 3.3 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Glyco_hydro_7 PF00840.20 KKF96734.1 - 6e-192 638.2 27.3 7.6e-192 637.8 27.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KKF96734.1 - 7.4e-09 35.4 8.0 7.4e-09 35.4 8.0 4.2 3 1 0 3 3 3 1 Fungal cellulose binding domain SNF5 PF04855.12 KKF96735.1 - 1.3e-87 293.6 0.0 1.7e-87 293.1 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KKF96735.1 - 3.5e-05 23.3 4.8 8e-05 22.2 4.8 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF4440 PF14534.6 KKF96735.1 - 0.098 13.1 0.2 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) BDHCT_assoc PF16204.5 KKF96735.1 - 0.17 11.5 0.1 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Rubredoxin_2 PF18073.1 KKF96735.1 - 4 7.2 9.7 0.19 11.5 1.3 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF3638 PF12340.8 KKF96736.1 - 1.5e-87 292.7 1.2 2.2e-87 292.1 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KKF96736.1 - 4.8e-16 57.8 0.3 1.1e-15 56.7 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) ParE_toxin PF05016.15 KKF96736.1 - 0.029 15.0 0.6 0.075 13.7 0.6 1.7 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Herpes_UL14 PF03580.14 KKF96736.1 - 0.034 14.4 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Choline_kinase PF01633.20 KKF96737.1 - 6.1e-53 179.6 0.0 5.5e-52 176.4 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KKF96737.1 - 4e-11 43.3 0.2 8.4e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KKF96737.1 - 0.0084 15.5 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF5129 PF17173.4 KKF96737.1 - 0.051 12.7 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) NPR3 PF03666.13 KKF96738.1 - 5.1e-127 424.5 10.9 2.8e-126 422.0 6.1 2.6 2 1 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 CUT PF02376.15 KKF96738.1 - 0.0099 16.0 0.5 0.042 14.0 0.4 2.1 2 0 0 2 2 2 1 CUT domain Glypican PF01153.19 KKF96738.1 - 0.22 10.3 5.7 0.39 9.5 5.7 1.4 1 0 0 1 1 1 0 Glypican HLH PF00010.26 KKF96739.1 - 5.1e-13 48.8 0.0 1.6e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain La PF05383.17 KKF96740.1 - 7.7e-17 61.1 0.1 1.4e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 La domain Gram_pos_anchor PF00746.21 KKF96741.1 - 0.53 10.3 0.0 0.53 10.3 0.0 2.9 4 0 0 4 4 4 0 LPXTG cell wall anchor motif FAM165 PF14981.6 KKF96741.1 - 9.7 6.1 5.5 1.7 8.5 0.1 2.4 3 0 0 3 3 3 0 FAM165 family TPR_19 PF14559.6 KKF96742.1 - 5.8e-25 87.6 2.1 1.9e-07 31.5 0.0 7.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKF96742.1 - 1e-23 81.9 22.2 0.015 16.1 1.2 10.9 7 3 5 12 12 12 7 Tetratricopeptide repeat HAT PF02184.16 KKF96742.1 - 2.9e-23 81.5 75.3 8.7e-14 51.2 1.8 13.0 14 0 0 14 14 14 6 HAT (Half-A-TPR) repeat Suf PF05843.14 KKF96742.1 - 8.5e-18 65.3 17.3 6.6e-07 29.6 1.4 6.1 4 2 1 5 5 5 4 Suppressor of forked protein (Suf) TPR_16 PF13432.6 KKF96742.1 - 2.8e-10 40.6 13.2 0.66 10.7 0.2 7.3 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKF96742.1 - 4.7e-10 38.8 19.0 0.34 11.1 0.1 9.3 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKF96742.1 - 5.1e-09 35.9 2.3 0.8 10.2 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKF96742.1 - 1.7e-07 31.5 13.1 2.8 8.8 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KKF96742.1 - 7.9e-06 25.3 12.5 0.014 14.7 2.5 5.2 2 1 1 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKF96742.1 - 1.2e-05 25.3 5.6 5.3 7.2 0.0 6.2 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 KKF96742.1 - 1.3e-05 25.0 7.6 1 9.7 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKF96742.1 - 0.0014 18.7 8.6 1.3 9.2 0.0 5.4 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKF96742.1 - 0.0092 16.3 18.1 0.8 10.0 0.0 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KKF96742.1 - 0.016 15.3 25.6 0.07 13.2 1.0 7.0 6 2 2 8 8 7 0 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 KKF96742.1 - 0.033 13.3 24.7 1.1 8.4 0.0 5.6 3 2 0 3 3 3 0 NRDE-2, necessary for RNA interference TPR_7 PF13176.6 KKF96742.1 - 0.038 14.0 11.8 3.3 8.0 0.2 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 KKF96742.1 - 0.23 11.6 4.7 83 3.4 0.3 4.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KKF96742.1 - 0.38 10.7 9.6 58 3.7 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4695 PF15766.5 KKF96742.1 - 0.54 10.5 4.8 0.52 10.6 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) Nop PF01798.18 KKF96743.1 - 3.7e-69 232.7 0.0 5.6e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KKF96743.1 - 9.3e-45 152.4 4.1 1.6e-44 151.6 1.7 2.5 2 1 0 2 2 2 1 Prp31 C terminal domain RRN3 PF05327.11 KKF96743.1 - 0.73 8.3 9.3 0.84 8.1 8.6 1.3 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1390 PF07150.11 KKF96744.1 - 0.16 11.6 0.3 0.3 10.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Acetate_kinase PF00871.17 KKF96745.1 - 9.2e-92 307.7 0.0 1.1e-91 307.5 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Collagen_mid PF15984.5 KKF96745.1 - 0.11 12.2 1.8 0.19 11.4 1.8 1.4 1 0 0 1 1 1 0 Bacterial collagen, middle region DMRL_synthase PF00885.19 KKF96746.1 - 1e-56 190.6 0.0 1.3e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF3682 PF12446.8 KKF96746.1 - 0.0062 17.0 3.0 0.0091 16.5 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) YL1 PF05764.13 KKF96747.1 - 0.0062 16.7 2.7 0.0062 16.7 2.7 2.3 2 0 0 2 2 2 1 YL1 nuclear protein Methyltransf_19 PF04672.12 KKF96747.1 - 0.017 14.6 0.2 0.68 9.4 0.0 2.2 2 0 0 2 2 2 0 S-adenosyl methyltransferase Cwf_Cwc_15 PF04889.12 KKF96747.1 - 0.44 10.2 14.7 0.34 10.6 8.6 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sulfatase PF00884.23 KKF96748.1 - 6.7e-62 209.6 1.8 9.4e-62 209.2 1.8 1.2 1 0 0 1 1 1 1 Sulfatase MFS_1 PF07690.16 KKF96748.1 - 1.5e-25 89.9 27.3 5.7e-25 88.0 27.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKF96748.1 - 1.2e-11 44.2 12.3 3.3e-09 36.1 7.0 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KKF96748.1 - 6.6e-09 34.7 6.1 1.2e-08 33.9 6.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phosphodiest PF01663.22 KKF96748.1 - 0.0042 16.7 1.4 0.089 12.4 1.4 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Cpn60_TCP1 PF00118.24 KKF96749.1 - 3.7e-172 573.4 0.8 4.2e-172 573.2 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.12 KKF96750.1 - 7.5e-39 132.7 8.8 7.5e-39 132.7 8.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) DUF966 PF06136.13 KKF96750.1 - 0.35 10.5 6.8 0.39 10.4 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4551 PF15087.6 KKF96750.1 - 1.6 7.5 5.6 1.8 7.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) LCD1 PF09798.9 KKF96750.1 - 3.3 6.1 6.3 3.9 5.9 6.3 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein His_Phos_1 PF00300.22 KKF96751.1 - 7.4e-28 97.6 0.0 1.3e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) P5-ATPase PF12409.8 KKF96751.1 - 0.035 14.2 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 P5-type ATPase cation transporter HATPase_c PF02518.26 KKF96752.1 - 4.9e-23 81.8 0.3 8.9e-23 80.9 0.3 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKF96752.1 - 4.7e-20 71.8 0.0 3.7e-19 68.9 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KKF96752.1 - 1.1e-19 70.2 0.2 2.6e-19 69.0 0.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain TEX33 PF15400.6 KKF96752.1 - 0.077 13.5 0.7 0.31 11.5 0.7 2.1 1 1 0 1 1 1 0 Testis-expressed sequence 33 protein family Allantoicase PF03561.15 KKF96753.1 - 8.7e-98 324.1 0.1 4.7e-48 162.8 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.19 KKF96754.1 - 4.8e-33 113.5 0.2 1.1e-32 112.4 0.2 1.7 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KKF96754.1 - 3.2e-08 34.0 0.0 0.011 16.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKF96754.1 - 2.8e-07 30.9 0.2 0.021 15.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKF96754.1 - 5.1e-07 29.8 0.0 0.00073 19.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KKF96754.1 - 6.6e-05 23.2 0.1 0.0062 16.9 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KKF96754.1 - 0.00077 19.7 0.0 2.3 9.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Auxin_repressed PF05564.12 KKF96754.1 - 0.037 14.7 0.2 0.11 13.2 0.2 1.8 1 0 0 1 1 1 0 Dormancy/auxin associated protein RabGAP-TBC PF00566.18 KKF96755.1 - 3.2e-34 118.5 0.0 4.7e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SWIB PF02201.18 KKF96756.1 - 2.7e-30 104.1 0.6 6.2e-30 102.9 0.6 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KKF96756.1 - 1.5e-14 53.6 0.4 3.9e-14 52.3 0.4 1.7 1 0 0 1 1 1 1 DEK C terminal domain Rcd1 PF04078.13 KKF96756.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like FliT PF05400.13 KKF96756.1 - 0.3 11.9 3.1 0.75 10.7 0.1 2.5 3 0 0 3 3 3 0 Flagellar protein FliT NatB_MDM20 PF09797.9 KKF96757.1 - 1.2e-32 113.3 0.0 2.1e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF3445 PF11927.8 KKF96758.1 - 2.5e-60 203.9 0.0 3.9e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Prenyltrans PF00432.21 KKF96758.1 - 5.1e-39 131.7 9.7 1.1e-08 34.7 0.0 6.4 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KKF96758.1 - 0.019 14.1 0.1 0.24 10.4 0.1 2.6 2 1 1 3 3 3 0 Squalene-hopene cyclase C-terminal domain Ribonuc_2-5A PF06479.12 KKF96760.1 - 7.1e-41 139.3 0.0 1.7e-40 138.1 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KKF96760.1 - 5.3e-29 101.4 0.0 2.4e-22 79.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96760.1 - 3.7e-14 52.6 0.0 8.7e-14 51.4 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase PQQ PF01011.21 KKF96760.1 - 7.2e-08 32.0 1.0 0.0047 16.8 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 KKF96760.1 - 2.7e-05 23.9 0.5 0.00056 19.6 0.4 2.6 1 1 1 2 2 2 2 PQQ-like domain Kdo PF06293.14 KKF96760.1 - 0.00096 18.6 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKF96760.1 - 0.028 14.3 7.5 0.056 13.4 0.1 3.3 3 1 1 4 4 4 0 Phosphotransferase enzyme family GAGA_bind PF06217.12 KKF96760.1 - 4.1 7.6 6.7 8.7 6.5 6.7 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family CVNH PF08881.10 KKF96761.1 - 2.7e-13 50.5 0.1 3.2e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 CVNH domain zf-like PF04071.12 KKF96761.1 - 5.8 6.9 9.0 1.5e+02 2.4 9.0 2.1 1 1 0 1 1 1 0 Cysteine-rich small domain 2-Hacid_dh_C PF02826.19 KKF96762.1 - 1.8e-51 174.0 0.0 2.7e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKF96762.1 - 3.9e-28 97.8 0.0 4.9e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKF96762.1 - 0.008 16.4 0.0 0.024 14.8 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KKF96762.1 - 0.063 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KKF96762.1 - 0.1 13.1 0.1 2.7 8.5 0.0 3.1 4 1 0 4 4 4 0 XdhC Rossmann domain IlvN PF07991.12 KKF96762.1 - 0.15 11.7 0.1 0.59 9.7 0.0 2.0 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KKF96762.1 - 0.23 10.7 1.0 8.6 5.6 1.0 2.2 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Dynamin_N PF00350.23 KKF96763.1 - 1.9e-29 102.9 2.9 2.3e-29 102.6 0.0 2.6 3 1 0 3 3 3 1 Dynamin family Dynamin_M PF01031.20 KKF96763.1 - 1e-15 57.8 0.0 5.2e-15 55.4 0.0 2.1 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KKF96763.1 - 6.5e-06 26.2 0.0 3e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KKF96763.1 - 0.047 14.2 0.8 0.21 12.1 0.0 2.4 3 0 0 3 3 3 0 ABC transporter Roc PF08477.13 KKF96763.1 - 0.082 13.1 0.0 0.28 11.4 0.0 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKF96763.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Ras family DUF913 PF06025.12 KKF96763.1 - 0.13 11.2 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) AAA_23 PF13476.6 KKF96763.1 - 0.55 10.7 4.2 6 7.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KKF96763.1 - 0.67 10.3 3.8 1 9.7 0.0 3.0 4 0 0 4 4 4 0 AAA ATPase domain FAR1 PF03101.15 KKF96764.1 - 0.0015 19.1 0.6 0.0015 19.1 0.6 3.4 3 1 1 4 4 4 1 FAR1 DNA-binding domain AFT PF08731.11 KKF96764.1 - 0.31 11.4 0.1 0.31 11.4 0.1 4.1 2 1 0 2 2 2 0 Transcription factor AFT GREB1 PF15782.5 KKF96764.1 - 1.8 5.6 33.8 2.8 4.9 33.8 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer WD40 PF00400.32 KKF96765.1 - 7.1e-56 184.9 26.5 2.6e-09 37.5 0.9 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF96765.1 - 8.2e-17 61.3 6.9 0.0015 18.8 0.6 4.9 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF96765.1 - 3.2e-06 26.3 0.3 1.1 8.1 0.0 4.4 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KKF96765.1 - 5.2e-06 26.5 0.2 0.0022 17.9 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KKF96765.1 - 0.00043 20.1 0.2 3.7 7.6 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat NLE PF08154.12 KKF96765.1 - 0.001 19.5 0.0 0.0027 18.2 0.0 1.7 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KKF96765.1 - 0.0039 15.9 9.5 0.56 8.8 0.1 4.8 5 2 0 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KKF96765.1 - 0.055 12.2 0.2 11 4.6 0.0 2.9 2 1 1 3 3 3 0 Nup133 N terminal like WD40_like PF17005.5 KKF96765.1 - 0.063 12.6 0.0 6 6.1 0.0 2.9 4 0 0 4 4 4 0 WD40-like domain FAD_binding_9 PF08021.11 KKF96765.1 - 0.083 13.1 0.0 0.64 10.2 0.0 2.4 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain DUF2610 PF11020.8 KKF96765.1 - 0.19 11.7 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2610) Gar1 PF04410.14 KKF96766.1 - 4e-45 153.3 0.0 1.3e-37 128.9 0.0 2.1 2 0 0 2 2 2 2 Gar1/Naf1 RNA binding region Osw5 PF17062.5 KKF96766.1 - 0.14 12.3 0.4 5.8 7.1 0.1 2.2 2 0 0 2 2 2 0 Outer spore wall 5 tRNA-synt_2b PF00587.25 KKF96767.1 - 6.7e-30 104.4 0.1 3.9e-28 98.6 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKF96767.1 - 1.2e-17 63.8 0.3 2.5e-17 62.8 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KKF96767.1 - 1.5e-09 37.7 0.0 4e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KKF96767.1 - 3.5e-09 36.6 0.0 7.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_His PF13393.6 KKF96767.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase CDP-OH_P_transf PF01066.21 KKF96768.1 - 3.3e-10 40.6 0.3 3.3e-10 40.6 0.3 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.8 KKF96769.1 - 5.2e-48 163.7 0.0 6.9e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KKF96769.1 - 0.0028 17.6 0.0 0.013 15.5 0.0 2.0 1 1 0 1 1 1 1 Jacalin-like lectin domain Peptidase_C14 PF00656.22 KKF96771.1 - 8.6e-60 202.8 0.4 1.3e-59 202.2 0.0 1.4 2 0 0 2 2 2 1 Caspase domain Raptor_N PF14538.6 KKF96771.1 - 0.12 12.3 2.0 0.12 12.3 0.1 2.1 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain Cnn_1N PF07989.11 KKF96772.1 - 4.4e-26 90.8 4.2 4.4e-26 90.8 4.2 19.0 7 5 9 18 18 18 3 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KKF96772.1 - 3.1e-21 75.7 0.6 3.1e-21 75.7 0.6 5.3 4 1 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF3450 PF11932.8 KKF96772.1 - 0.0012 18.2 8.2 0.0012 18.2 8.2 15.0 3 3 11 14 14 14 1 Protein of unknown function (DUF3450) HALZ PF02183.18 KKF96772.1 - 0.018 15.2 1.6 0.018 15.2 1.6 12.9 12 2 1 13 13 13 0 Homeobox associated leucine zipper Spc7 PF08317.11 KKF96772.1 - 1.5 7.7 245.3 0.36 9.7 16.2 11.5 1 1 10 12 12 12 0 Spc7 kinetochore protein DUF3866 PF12982.7 KKF96772.1 - 9.5 5.2 10.0 1.1 8.3 0.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3866) YccV-like PF08755.11 KKF96773.1 - 2.6e-08 34.3 0.0 4.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.7 KKF96773.1 - 7.4e-05 22.6 0.1 0.00017 21.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKF96773.1 - 0.0039 17.0 0.2 0.0091 15.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain Peptidase_C12 PF01088.21 KKF96774.1 - 2.7e-51 174.3 0.1 3.7e-51 173.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ig_3 PF13927.6 KKF96775.1 - 0.022 15.3 0.5 2.9 8.6 0.0 4.1 5 0 0 5 5 5 0 Immunoglobulin domain I-set PF07679.16 KKF96775.1 - 0.038 14.0 0.1 14 5.8 0.0 4.3 4 0 0 4 4 4 0 Immunoglobulin I-set domain AltA1 PF16541.5 KKF96775.1 - 0.052 14.4 0.1 2.6 8.9 0.0 2.7 2 0 0 2 2 2 0 Alternaria alternata allergen 1 DUF1918 PF08940.11 KKF96775.1 - 0.33 10.6 2.5 13 5.5 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF1918) Nrap_D4 PF17405.2 KKF96776.1 - 2.9e-54 183.7 0.0 5.3e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KKF96776.1 - 2.5e-50 170.4 0.1 7.1e-50 168.9 0.1 1.8 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KKF96776.1 - 2.4e-43 147.5 0.0 1.3e-40 138.6 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 KKF96776.1 - 3.3e-40 137.6 0.4 5.2e-40 137.0 0.4 1.3 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KKF96776.1 - 9.2e-40 136.3 0.0 1.9e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KKF96776.1 - 3.7e-28 98.4 0.0 6.7e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 PP28 PF10252.9 KKF96778.1 - 5.2e-24 84.5 17.4 5.2e-24 84.5 17.4 3.1 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Bap31 PF05529.12 KKF96780.1 - 5.9e-47 158.9 9.3 8.2e-47 158.4 9.3 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KKF96780.1 - 7.9e-12 45.0 6.1 1.2e-11 44.4 6.1 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4446 PF14584.6 KKF96780.1 - 0.0048 16.9 0.4 0.0048 16.9 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4446) DivIC PF04977.15 KKF96780.1 - 0.012 15.3 3.8 0.065 13.0 1.3 2.7 3 0 0 3 3 3 0 Septum formation initiator APG6_N PF17675.1 KKF96780.1 - 0.063 13.8 3.3 0.12 12.9 3.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region KELK PF15796.5 KKF96780.1 - 0.11 13.0 2.9 0.19 12.2 2.9 1.4 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PhoLip_ATPase_C PF16212.5 KKF96780.1 - 0.92 9.2 9.9 0.69 9.6 8.1 1.6 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal UPF0242 PF06785.11 KKF96780.1 - 6.1 6.9 9.6 29 4.7 9.6 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pil1 PF13805.6 KKF96781.1 - 2e-125 417.6 0.4 3.5e-125 416.8 0.4 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 Octopine_DH PF02317.17 KKF96781.1 - 0.061 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain XPG_I PF00867.18 KKF96782.1 - 6.5e-27 93.7 0.0 2e-26 92.2 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KKF96782.1 - 0.026 15.1 0.0 0.09 13.4 0.0 1.9 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Mvb12 PF09452.10 KKF96782.1 - 7.3 7.1 7.7 17 5.9 0.1 3.8 4 0 0 4 4 4 0 ESCRT-I subunit Mvb12 NACHT_N PF17100.5 KKF96783.1 - 5.9e-54 183.2 2.6 5.9e-54 183.2 2.6 1.6 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KKF96783.1 - 1.2e-05 25.3 0.1 4e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_11 PF13086.6 KKF96783.1 - 0.0034 17.2 5.2 0.48 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain PIN_8 PF18476.1 KKF96783.1 - 0.021 14.7 8.7 0.017 15.0 7.3 1.6 2 0 0 2 2 2 0 PIN like domain TsaE PF02367.17 KKF96783.1 - 0.063 13.3 0.7 1.4 9.0 0.0 2.8 3 1 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KKF96783.1 - 0.13 12.6 0.2 0.81 10.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase FapA PF03961.13 KKF96783.1 - 0.17 10.5 1.5 0.28 9.8 1.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Peroxin-13_N PF04088.13 KKF96784.1 - 1.1e-51 174.9 0.1 1.8e-51 174.2 0.1 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KKF96784.1 - 2.9e-10 39.7 0.0 5.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKF96784.1 - 3.2e-06 26.6 0.0 9e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKF96784.1 - 3.6e-06 26.7 0.0 6.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KKF96784.1 - 0.021 15.2 0.0 0.08 13.4 0.0 1.8 1 1 1 2 2 2 0 Helically-extended SH3 domain RVT_1 PF00078.27 KKF96785.1 - 1.2e-33 116.5 0.0 1.7e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ADH_N PF08240.12 KKF96786.1 - 5.5e-27 93.8 1.8 1e-26 93.0 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKF96786.1 - 1e-16 61.1 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKF96786.1 - 1.6e-07 31.0 0.4 5.4e-05 22.8 0.3 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ATP-synt_G PF04718.15 KKF96787.1 - 2.5e-24 86.0 0.1 4.2e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit TFIIA PF03153.13 KKF96788.1 - 1.5e-74 252.5 16.8 1.9e-71 242.2 16.8 2.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 KKF96788.1 - 0.67 9.6 10.6 0.4 10.4 8.8 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 KKF96789.1 - 3.3e-19 68.9 14.9 0.00084 20.1 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF96789.1 - 1.7e-17 63.5 5.6 8.6e-06 26.0 0.3 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKF96789.1 - 5.1e-07 29.0 0.1 0.00029 19.9 0.0 3.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KKF96789.1 - 8.7e-06 25.7 0.2 0.0014 18.5 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PSII_BNR PF14870.6 KKF96789.1 - 0.021 14.1 0.8 0.036 13.3 0.3 1.5 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 PALB2_WD40 PF16756.5 KKF96789.1 - 0.098 11.6 0.5 0.21 10.4 0.5 1.5 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain BTB PF00651.31 KKF96790.1 - 3e-10 40.3 0.0 4.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KKF96790.1 - 0.021 14.9 0.0 0.089 12.9 0.0 1.9 1 1 0 2 2 2 0 BTB And C-terminal Kelch zf-C2H2_4 PF13894.6 KKF96791.1 - 0.0016 19.1 14.7 0.42 11.6 0.4 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KKF96791.1 - 0.0031 17.7 4.7 0.048 13.8 0.2 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KKF96791.1 - 0.0057 17.0 14.5 0.042 14.3 1.2 3.9 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-MYST PF17772.1 KKF96791.1 - 0.055 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 MYST family zinc finger domain HTH_24 PF13412.6 KKF96791.1 - 0.084 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CHORD PF04968.12 KKF96791.1 - 0.95 10.2 4.0 29 5.5 0.1 2.6 2 0 0 2 2 2 0 CHORD HIG_1_N PF04588.13 KKF96792.1 - 9.9e-05 22.5 0.5 9.9e-05 22.5 0.5 2.2 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF4079 PF13301.6 KKF96792.1 - 0.021 14.9 0.2 0.035 14.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Romo1 PF10247.9 KKF96792.1 - 0.031 14.6 2.1 0.069 13.5 2.1 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Trep_Strep PF09605.10 KKF96792.1 - 0.094 12.7 0.7 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) IRK_N PF08466.10 KKF96792.1 - 0.14 12.3 0.6 0.34 11.1 0.1 2.0 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal Sigma70_r1_2 PF00140.20 KKF96792.1 - 4.6 7.4 4.8 42 4.3 0.1 3.0 3 0 0 3 3 3 0 Sigma-70 factor, region 1.2 ADH_N PF08240.12 KKF96793.1 - 7.1e-31 106.3 2.2 1.4e-30 105.3 0.1 2.5 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKF96793.1 - 1e-24 87.0 0.6 1.8e-24 86.2 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKF96793.1 - 5e-12 45.8 1.1 8e-12 45.1 1.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKF96793.1 - 6.6e-07 30.5 0.1 2.3e-06 28.7 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKF96793.1 - 0.00031 20.1 2.0 0.00046 19.6 2.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KKF96793.1 - 0.0013 18.0 0.3 0.0031 16.8 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKF96793.1 - 0.0054 15.5 0.9 0.0099 14.6 0.9 1.4 1 0 0 1 1 1 1 HI0933-like protein PALP PF00291.25 KKF96793.1 - 0.0057 16.1 0.7 0.0085 15.5 0.7 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UDPG_MGDP_dh_N PF03721.14 KKF96793.1 - 0.0067 16.0 0.2 0.012 15.2 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cas_csx3 PF09620.10 KKF96793.1 - 0.045 13.7 0.3 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_csx3) FAD_binding_3 PF01494.19 KKF96793.1 - 0.046 13.0 0.3 0.072 12.3 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KKF96793.1 - 0.071 12.4 0.7 0.13 11.4 0.3 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KKF96793.1 - 0.077 13.3 0.5 0.12 12.6 0.1 1.6 2 0 0 2 2 1 0 TrkA-N domain Pyr_redox PF00070.27 KKF96793.1 - 0.087 13.4 0.4 0.2 12.2 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KKF96793.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KKF96793.1 - 0.57 10.2 3.5 0.33 11.0 0.6 2.0 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Isochorismatase PF00857.20 KKF96794.1 - 1.1e-24 87.5 0.1 6.1e-24 85.1 0.1 1.8 1 1 0 1 1 1 1 Isochorismatase family HMG-CoA_red PF00368.18 KKF96795.1 - 1.6e-141 471.6 4.3 2.2e-141 471.2 4.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KKF96795.1 - 1.6e-24 86.5 0.3 3.3e-24 85.5 0.3 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KKF96795.1 - 1.9e-14 53.8 6.2 1.1e-13 51.3 6.2 2.1 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KKF96795.1 - 2.5e-07 29.2 3.6 2.5e-07 29.2 3.6 1.7 2 0 0 2 2 2 1 Patched family DUF4260 PF14079.6 KKF96795.1 - 3.4 7.7 5.5 0.61 10.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4260) Vint PF14623.6 KKF96796.1 - 2.2e-49 167.5 0.7 2e-33 115.5 0.1 2.2 2 0 0 2 2 2 2 Hint-domain Hint PF01079.20 KKF96796.1 - 0.0061 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Hint module UPF0052 PF01933.18 KKF96797.1 - 3.5e-59 200.4 0.0 5e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF3176 PF11374.8 KKF96800.1 - 1.1e-16 61.0 1.4 2e-16 60.1 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Cwf_Cwc_15 PF04889.12 KKF96802.1 - 0.051 13.3 3.4 0.069 12.9 3.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NAM-associated PF14303.6 KKF96802.1 - 1.6 9.4 10.0 0.11 13.2 4.2 1.9 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Ndc1_Nup PF09531.10 KKF96804.1 - 5.9 5.5 8.0 8.7 4.9 8.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AZUL PF16558.5 KKF96805.1 - 4.3e-07 30.1 0.2 4.3e-07 30.1 0.2 2.8 4 0 0 4 4 4 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-LYAR PF08790.11 KKF96805.1 - 0.0043 16.9 3.0 1.5 8.8 1.1 2.7 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 KKF96805.1 - 0.0094 16.4 18.1 0.17 12.4 0.1 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKF96805.1 - 0.0098 16.7 22.0 0.58 11.1 1.0 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger TRAF6_Z2 PF18048.1 KKF96805.1 - 0.043 13.9 1.0 0.043 13.9 1.0 2.7 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zinc-ribbons_6 PF07191.12 KKF96805.1 - 0.28 11.2 14.7 36 4.4 10.3 4.5 2 1 1 3 3 3 0 zinc-ribbons zf_C2HC_14 PF18574.1 KKF96805.1 - 0.45 10.3 7.4 0.14 12.0 1.1 2.9 2 0 0 2 2 2 0 C2HC Zing finger domain zf_UBZ PF18439.1 KKF96805.1 - 1 9.0 19.0 0.36 10.5 0.2 4.6 4 1 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 KKF96805.1 - 1.9 8.5 8.7 1.9 8.5 0.5 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-Mss51 PF13824.6 KKF96805.1 - 5.9 7.1 9.7 10 6.3 2.6 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Methuselah_N PF06652.12 KKF96806.1 - 0.028 14.3 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 Methuselah N-terminus Actin PF00022.19 KKF96807.1 - 2.8e-82 276.5 0.0 3.4e-81 272.9 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKF96807.1 - 0.017 14.0 0.0 0.076 11.8 0.0 2.0 3 0 0 3 3 3 0 MreB/Mbl protein Aldo_ket_red PF00248.21 KKF96808.1 - 3.7e-50 170.8 0.0 4.6e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.24 KKF96809.1 - 6.2e-41 140.7 3.4 1.9e-40 139.1 3.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Gln-synt_N PF03951.19 KKF96809.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain ThrE PF06738.12 KKF96809.1 - 0.67 9.3 5.5 0.86 8.9 0.1 2.3 2 0 0 2 2 2 0 Putative threonine/serine exporter RNA_polI_A34 PF08208.11 KKF96810.1 - 4.8e-28 98.7 21.7 4.8e-28 98.7 21.7 5.4 3 2 1 4 4 4 2 DNA-directed RNA polymerase I subunit RPA34.5 CLP1_P PF16575.5 KKF96811.1 - 1.4e-22 80.4 0.0 7.9e-22 78.0 0.0 1.9 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ABC_tran PF00005.27 KKF96811.1 - 0.0043 17.6 0.2 0.033 14.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ATPase_2 PF01637.18 KKF96811.1 - 0.0089 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KKF96811.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKF96811.1 - 0.022 15.3 0.0 0.045 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKF96811.1 - 0.026 14.4 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 KKF96811.1 - 0.053 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 KKF96811.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.6 KKF96811.1 - 0.075 13.5 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KKF96811.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KKF96811.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KKF96811.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKF96811.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain VirE PF05272.11 KKF96811.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E UPF0242 PF06785.11 KKF96812.1 - 9.9e-10 38.8 55.5 0.00018 21.6 13.5 5.8 3 1 2 5 5 5 3 Uncharacterised protein family (UPF0242) N-terminus DUF4686 PF15742.5 KKF96812.1 - 1.2e-06 28.0 42.2 1.2e-06 28.0 42.2 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4686) Tropomyosin_1 PF12718.7 KKF96812.1 - 4.3e-06 26.9 60.5 0.0032 17.6 10.8 6.6 5 2 1 6 6 6 3 Tropomyosin like Spc7 PF08317.11 KKF96812.1 - 5.3e-06 25.5 70.7 0.029 13.3 12.0 7.0 4 2 4 8 8 8 4 Spc7 kinetochore protein FlaC_arch PF05377.11 KKF96812.1 - 1.8e-05 25.0 27.5 0.049 14.0 0.3 8.0 6 2 4 10 10 8 2 Flagella accessory protein C (FlaC) Myosin_tail_1 PF01576.19 KKF96812.1 - 6.8e-05 20.9 29.0 6.8e-05 20.9 29.0 4.9 3 1 2 5 5 5 1 Myosin tail ATG16 PF08614.11 KKF96812.1 - 0.00012 22.4 88.4 0.00046 20.5 20.3 7.3 5 2 2 7 7 7 4 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KKF96812.1 - 0.00016 21.7 18.0 0.00016 21.7 18.0 7.3 5 3 2 7 7 7 2 TPR/MLP1/MLP2-like protein Gp58 PF07902.11 KKF96812.1 - 0.00024 19.6 33.0 0.0032 15.9 8.4 2.9 1 1 1 2 2 2 2 gp58-like protein DUF724 PF05266.14 KKF96812.1 - 0.00041 20.2 12.7 0.0014 18.5 1.6 6.3 3 1 4 7 7 7 2 Protein of unknown function (DUF724) AAA_13 PF13166.6 KKF96812.1 - 0.00041 19.1 21.7 0.00041 19.1 21.7 4.9 2 1 4 6 6 6 3 AAA domain ADIP PF11559.8 KKF96812.1 - 0.00083 19.5 77.4 0.026 14.6 5.7 8.3 4 1 4 8 8 8 4 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KKF96812.1 - 0.00088 19.2 54.4 0.35 10.9 0.3 9.9 6 1 4 10 10 10 4 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KKF96812.1 - 0.0051 17.4 66.1 0.27 11.9 1.2 10.0 8 2 3 11 11 9 3 SlyX Baculo_PEP_C PF04513.12 KKF96812.1 - 0.0071 16.4 7.2 0.0071 16.4 7.2 6.0 4 1 3 7 7 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus BRE1 PF08647.11 KKF96812.1 - 0.0093 16.0 7.5 0.0093 16.0 7.5 8.1 5 1 3 8 8 8 4 BRE1 E3 ubiquitin ligase DUF1699 PF08004.11 KKF96812.1 - 0.021 14.5 1.6 1.8 8.3 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) KASH_CCD PF14662.6 KKF96812.1 - 0.054 13.3 52.2 0.017 14.9 16.2 6.0 3 1 3 6 6 6 0 Coiled-coil region of CCDC155 or KASH Evr1_Alr PF04777.13 KKF96812.1 - 0.07 13.6 2.0 0.96 10.0 0.3 3.1 2 0 0 2 2 2 0 Erv1 / Alr family TMF_TATA_bd PF12325.8 KKF96812.1 - 0.1 12.9 58.9 0.23 11.7 2.5 7.2 4 2 3 7 7 7 0 TATA element modulatory factor 1 TATA binding Filament PF00038.21 KKF96812.1 - 0.13 11.9 73.6 0.073 12.7 3.2 6.7 3 1 4 7 7 7 0 Intermediate filament protein Atg14 PF10186.9 KKF96812.1 - 0.13 11.3 63.8 0.023 13.8 7.9 6.2 3 1 3 7 7 7 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5082 PF16888.5 KKF96812.1 - 0.16 12.2 55.9 0.014 15.6 13.3 8.4 4 3 3 7 7 7 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 KKF96812.1 - 0.18 11.2 74.5 1.8 7.8 3.8 6.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KKF96812.1 - 0.51 10.8 68.8 0.68 10.4 1.0 6.4 2 1 2 4 4 3 0 Fez1 SpoOE-like PF09388.10 KKF96812.1 - 0.6 10.0 0.0 0.6 10.0 0.0 3.7 5 0 0 5 5 4 0 Spo0E like sporulation regulatory protein DUF812 PF05667.11 KKF96812.1 - 2.2 7.0 60.0 0.22 10.4 11.9 5.0 1 1 4 5 5 5 0 Protein of unknown function (DUF812) Cast PF10174.9 KKF96812.1 - 4 5.6 56.9 0.061 11.6 18.3 4.1 2 1 1 4 4 4 0 RIM-binding protein of the cytomatrix active zone GAS PF13851.6 KKF96812.1 - 4.9 6.5 66.7 0.49 9.7 20.7 6.7 4 2 2 6 6 6 0 Growth-arrest specific micro-tubule binding DUF4618 PF15397.6 KKF96812.1 - 4.9 6.5 48.9 0.37 10.2 13.4 5.6 3 1 2 5 5 5 0 Domain of unknown function (DUF4618) DUF1216 PF06746.11 KKF96812.1 - 7.5 6.6 14.5 1 9.4 1.5 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1216) FPP PF05911.11 KKF96812.1 - 9 4.3 59.4 0.17 10.0 21.6 3.8 1 1 2 4 4 4 0 Filament-like plant protein, long coiled-coil ABC_membrane PF00664.23 KKF96813.1 - 7.1e-39 134.1 13.1 9e-39 133.8 13.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKF96813.1 - 4.3e-35 121.2 0.0 9.5e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKF96813.1 - 7.3e-06 25.6 0.0 0.0046 16.4 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKF96813.1 - 0.00037 20.4 0.1 0.009 15.8 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKF96813.1 - 0.00056 20.3 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKF96813.1 - 0.0007 19.9 0.0 0.0026 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKF96813.1 - 0.001 18.8 0.0 0.0027 17.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KKF96813.1 - 0.006 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 KKF96813.1 - 0.0072 16.8 0.0 0.061 13.8 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKF96813.1 - 0.015 15.3 0.0 0.08 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKF96813.1 - 0.02 14.6 0.1 0.05 13.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KKF96813.1 - 0.02 14.8 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KKF96813.1 - 0.024 14.7 0.0 0.088 12.9 0.0 2.0 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 KKF96813.1 - 0.026 14.1 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKF96813.1 - 0.038 14.2 0.0 0.085 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KKF96813.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KKF96813.1 - 0.081 13.1 0.0 0.36 11.0 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KKF96813.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KKF96813.1 - 0.097 13.2 0.0 0.36 11.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 KKF96813.1 - 0.099 13.1 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2457 PF10446.9 KKF96814.1 - 0.004 16.4 32.4 0.004 16.4 32.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) SDA1 PF05285.12 KKF96814.1 - 0.007 15.8 26.8 0.0072 15.8 26.8 1.2 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 KKF96814.1 - 0.0099 14.4 24.0 0.0097 14.4 24.0 1.1 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 KKF96814.1 - 0.012 13.9 28.6 0.012 13.9 28.6 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KKF96814.1 - 0.025 12.9 23.0 0.024 12.9 23.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 KKF96814.1 - 0.069 12.1 24.7 0.073 12.1 24.7 1.1 1 0 0 1 1 1 0 Paf1 Polyoma_lg_T_C PF06431.11 KKF96814.1 - 0.083 11.7 6.9 0.1 11.5 6.9 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Usp PF00582.26 KKF96814.1 - 0.11 13.0 6.6 0.15 12.6 6.6 1.2 1 0 0 1 1 1 0 Universal stress protein family CobT PF06213.12 KKF96814.1 - 0.13 11.7 27.6 0.16 11.4 27.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 KKF96814.1 - 0.14 11.2 6.8 0.15 11.0 6.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 KKF96814.1 - 0.15 12.4 14.7 0.16 12.3 14.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 KKF96814.1 - 0.15 12.0 14.5 0.18 11.7 14.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 KKF96814.1 - 0.26 10.6 23.1 0.28 10.5 23.1 1.2 1 0 0 1 1 1 0 BUD22 RNA_polI_A34 PF08208.11 KKF96814.1 - 0.4 10.8 16.4 0.41 10.7 16.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Astro_capsid_p PF12226.8 KKF96814.1 - 0.44 9.6 26.2 0.51 9.5 26.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC27 PF09507.10 KKF96814.1 - 0.44 9.9 18.2 0.46 9.8 18.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DNA_pol_phi PF04931.13 KKF96814.1 - 0.73 7.9 42.4 0.86 7.6 42.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi CPSF100_C PF13299.6 KKF96814.1 - 0.75 10.0 9.5 0.78 9.9 9.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 KKF96814.1 - 0.79 8.9 7.1 0.85 8.8 7.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Trypan_PARP PF05887.11 KKF96814.1 - 0.79 9.7 18.0 0.88 9.5 18.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.12 KKF96814.1 - 0.82 9.4 13.4 0.86 9.4 13.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SGT1 PF07093.11 KKF96814.1 - 1.5 7.2 15.2 1.5 7.1 15.2 1.2 1 0 0 1 1 1 0 SGT1 protein Serinc PF03348.15 KKF96814.1 - 1.5 7.7 3.9 1.7 7.5 3.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) PPL5 PF18168.1 KKF96814.1 - 1.8 7.8 7.4 1.9 7.7 7.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 V_ATPase_I PF01496.19 KKF96814.1 - 2.6 5.8 10.7 2.9 5.7 10.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-3c_N PF05470.12 KKF96814.1 - 3.4 5.9 15.7 3.3 5.9 15.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2428 PF10350.9 KKF96814.1 - 4 6.6 9.1 5 6.3 9.1 1.1 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) DUF2722 PF10846.8 KKF96814.1 - 4.1 6.2 14.4 4.4 6.1 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SAPS PF04499.15 KKF96814.1 - 4.5 6.0 12.7 4.7 5.9 12.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 KKF96814.1 - 4.9 5.8 10.7 5.2 5.7 10.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SspB PF04386.13 KKF96814.1 - 5.7 6.8 15.2 7.5 6.4 15.2 1.2 1 0 0 1 1 1 0 Stringent starvation protein B RAB3GAP2_C PF14656.6 KKF96814.1 - 5.7 5.0 6.5 6.9 4.8 6.5 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF2971 PF11185.8 KKF96814.1 - 6 8.1 12.3 8.1 7.7 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2971) Presenilin PF01080.17 KKF96814.1 - 6.7 5.4 11.4 7.1 5.3 11.4 1.0 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 KKF96814.1 - 6.9 6.6 7.9 8.5 6.3 7.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.8 KKF96814.1 - 7.3 5.3 14.3 9 5.0 14.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 KKF96814.1 - 9.2 5.9 10.8 9.6 5.9 10.8 1.3 1 1 0 1 1 1 0 Connexin CP2 PF04516.15 KKF96815.1 - 5.2e-51 173.2 0.0 2.3e-50 171.1 0.0 1.9 2 0 0 2 2 2 1 CP2 transcription factor Oxysterol_BP PF01237.18 KKF96816.1 - 4e-40 137.8 0.0 4.2e-38 131.2 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein MAM33 PF02330.16 KKF96817.1 - 1.8e-60 204.5 6.0 2.3e-60 204.2 6.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein tRNA-synt_His PF13393.6 KKF96817.1 - 0.052 12.8 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Retinal PF15449.6 KKF96817.1 - 1.5 6.5 4.8 0.3 8.8 0.1 1.8 2 0 0 2 2 2 0 Retinal protein Tma16 PF11176.8 KKF96818.1 - 6.4e-43 146.1 1.1 8.4e-43 145.7 1.1 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 XPG_N PF00752.17 KKF96819.1 - 1.4e-23 83.2 0.0 2.6e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KKF96819.1 - 5.1e-19 68.4 0.1 1.2e-18 67.2 0.0 1.6 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 KKF96819.1 - 3.9e-05 23.2 0.0 7.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing TPR_8 PF13181.6 KKF96819.1 - 0.0088 16.2 0.0 0.028 14.6 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKF96819.1 - 0.025 14.7 0.0 0.062 13.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKF96819.1 - 0.038 13.8 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Redoxin PF08534.10 KKF96820.1 - 2.4e-27 95.4 0.0 2.9e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KKF96820.1 - 2.3e-07 30.8 0.0 3.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family zf-C2H2_4 PF13894.6 KKF96821.1 - 4 8.6 7.2 5.1 8.2 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Abhydrolase_2 PF02230.16 KKF96823.1 - 3.5e-25 89.1 0.0 3.7e-23 82.5 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase APH PF01636.23 KKF96823.1 - 4.5e-13 49.7 0.0 7.5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKF96823.1 - 1.7e-05 24.6 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KKF96823.1 - 0.0008 18.8 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96823.1 - 0.016 14.5 0.0 0.035 13.4 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase FSH1 PF03959.13 KKF96823.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Glyco_hydro_16 PF00722.21 KKF96824.1 - 3.2e-41 140.7 1.9 8.2e-41 139.4 1.9 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RGS PF00615.19 KKF96825.1 - 4.7e-06 26.9 0.0 0.0038 17.5 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Cytochrom_B_C PF00032.17 KKF96825.1 - 0.066 13.5 1.8 1.1 9.6 0.4 3.0 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Glyco_hydro_5_C PF18564.1 KKF96826.1 - 5.7e-19 68.4 0.1 6.7e-18 65.0 0.0 2.5 2 1 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KKF96826.1 - 7.1e-10 38.8 0.4 3.8e-06 26.5 0.6 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) MAGSP PF03082.14 KKF96826.1 - 0.16 11.5 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Male accessory gland secretory protein Vps51 PF08700.11 KKF96827.1 - 1.8e-25 88.8 0.1 4.5e-25 87.5 0.1 1.8 1 0 0 1 1 1 1 Vps51/Vps67 TPR_16 PF13432.6 KKF96827.1 - 5.2e-25 87.8 37.9 6.4e-05 23.5 2.5 11.6 12 1 2 14 14 12 6 Tetratricopeptide repeat TPR_17 PF13431.6 KKF96827.1 - 1.5e-24 84.6 15.5 0.025 15.0 0.0 12.3 13 0 0 13 13 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 KKF96827.1 - 1.6e-23 83.0 22.7 1.6e-05 25.3 3.3 11.2 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 KKF96827.1 - 9e-23 78.5 64.0 0.0031 17.5 0.7 17.6 19 0 0 19 19 18 7 Tetratricopeptide repeat TPR_12 PF13424.6 KKF96827.1 - 4.2e-22 78.2 37.4 9.7e-05 22.6 0.9 12.2 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 KKF96827.1 - 1.4e-21 75.3 43.4 0.0046 16.7 0.0 14.6 17 0 0 17 17 15 6 Tetratricopeptide repeat TPR_14 PF13428.6 KKF96827.1 - 6.1e-20 70.2 30.1 0.014 16.1 0.8 15.5 12 4 5 17 17 16 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKF96827.1 - 5.9e-19 67.5 22.8 0.00039 20.0 0.0 11.4 10 1 1 11 11 11 5 TPR repeat TPR_8 PF13181.6 KKF96827.1 - 1.9e-15 55.7 42.0 0.049 13.9 0.4 15.2 17 0 0 17 17 16 5 Tetratricopeptide repeat TPR_7 PF13176.6 KKF96827.1 - 1e-08 34.6 17.0 0.047 13.7 0.1 10.3 9 1 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF96827.1 - 3.6e-06 27.1 17.8 0.2 11.9 1.2 7.5 6 1 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KKF96827.1 - 4.9e-06 26.8 29.2 1.4 9.7 0.1 11.8 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKF96827.1 - 5.7e-06 26.4 13.5 0.64 10.2 0.0 7.4 7 1 0 7 7 7 3 Tetratricopeptide repeat Dor1 PF04124.12 KKF96827.1 - 0.00016 20.5 2.1 0.00017 20.4 0.4 1.8 2 0 0 2 2 2 1 Dor1-like family TPR_22 PF18833.1 KKF96827.1 - 0.00089 19.3 0.4 0.0068 16.5 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KKF96827.1 - 0.0053 16.2 0.3 0.0053 16.2 0.3 4.9 6 0 0 6 6 6 1 MalT-like TPR region BTAD PF03704.17 KKF96827.1 - 1.9 8.9 8.6 7.3 7.0 0.0 4.7 4 0 0 4 4 4 0 Bacterial transcriptional activator domain DUF2225 PF09986.9 KKF96827.1 - 2.1 8.0 5.6 9.3 5.9 0.0 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) NIF3 PF01784.18 KKF96828.1 - 3.4e-29 102.2 0.2 2.1e-18 66.8 0.0 2.0 1 1 1 2 2 2 2 NIF3 (NGG1p interacting factor 3) NIF3 PF01784.18 KKF96829.1 - 1.3e-55 188.8 0.0 1.6e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF4197 PF13852.6 KKF96829.1 - 0.12 12.0 0.1 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4197) BolA PF01722.18 KKF96830.1 - 2.8e-18 66.0 0.0 4.2e-18 65.4 0.0 1.3 1 1 0 1 1 1 1 BolA-like protein Adaptin_N PF01602.20 KKF96831.1 - 1.8e-135 452.5 3.8 2.4e-135 452.0 3.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KKF96831.1 - 7.8e-64 214.6 2.1 1.7e-61 207.0 0.1 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKF96831.1 - 7e-16 58.4 2.5 5.1e-07 30.0 0.0 6.2 2 1 6 8 8 8 3 HEAT repeats HEAT PF02985.22 KKF96831.1 - 1.4e-11 43.6 4.2 0.021 15.1 0.0 6.4 6 0 0 6 6 5 2 HEAT repeat Arm PF00514.23 KKF96831.1 - 2.6e-05 24.1 0.7 0.1 12.7 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 KKF96831.1 - 0.0038 17.2 0.3 0.05 13.6 0.0 2.5 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 KKF96831.1 - 0.0074 16.8 5.9 0.64 10.6 0.0 5.1 4 1 1 5 5 5 1 HEAT-like repeat CSTF2_hinge PF14327.6 KKF96831.1 - 0.01 16.3 0.4 2.5 8.6 0.2 3.3 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 RTP1_C1 PF10363.9 KKF96831.1 - 0.014 15.6 0.5 0.69 10.1 0.0 3.7 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KKF96831.1 - 0.049 13.2 0.1 2 7.9 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal RasGEF_N_2 PF14663.6 KKF96831.1 - 0.095 13.1 0.3 2.3 8.7 0.0 3.1 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RIX1 PF08167.12 KKF96831.1 - 0.13 12.0 1.2 9.9 5.8 0.0 3.2 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis NifU PF01106.17 KKF96831.1 - 0.38 11.0 1.2 0.78 9.9 0.5 2.0 2 0 0 2 2 1 0 NifU-like domain DNA_ligase_A_M PF01068.21 KKF96832.1 - 4.8e-32 111.3 0.1 8.2e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 KKF96832.1 - 4e-19 69.1 0.0 8.3e-18 64.8 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region CSN8_PSD8_EIF3K PF10075.9 KKF96833.1 - 5.6e-37 126.9 0.0 7.6e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KKF96833.1 - 0.023 14.1 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 SAC3/GANP family DUF3453 PF11935.8 KKF96833.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) PDCD2_C PF04194.13 KKF96834.1 - 1.2e-45 155.7 0.0 2.2e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Cpn60_TCP1 PF00118.24 KKF96835.1 - 3.2e-161 537.3 0.1 3.6e-161 537.1 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_47 PF01532.20 KKF96836.1 - 1.5e-182 607.6 0.1 1.8e-182 607.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.25 KKF96837.1 - 2.1e-62 210.9 0.0 5.5e-62 209.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96837.1 - 1.4e-46 158.9 0.0 2.7e-46 157.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF96837.1 - 3e-07 30.0 0.0 6.2e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KKF96837.1 - 0.0032 16.3 0.1 0.0047 15.7 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KKF96837.1 - 0.007 15.7 0.0 0.017 14.5 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKF96837.1 - 0.038 13.9 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family AIM24 PF01987.17 KKF96838.1 - 8.4e-45 153.0 0.1 1e-44 152.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PUF PF00806.19 KKF96840.1 - 7.9e-13 47.3 0.0 0.47 10.2 0.0 6.5 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat HUN PF08729.10 KKF96841.1 - 1e-07 31.8 0.2 1e-07 31.8 0.2 1.9 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Epimerase PF01370.21 KKF96842.1 - 5.4e-17 62.1 0.0 8.7e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKF96842.1 - 3.1e-15 55.9 0.0 4.6e-15 55.4 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKF96842.1 - 2.8e-09 36.8 0.0 9.1e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KKF96842.1 - 4.6e-08 32.5 0.3 0.0004 19.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KKF96842.1 - 7.7e-06 25.6 0.5 0.0019 17.8 0.2 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KKF96842.1 - 4e-05 23.6 0.0 6.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KKF96842.1 - 0.00029 20.1 0.2 0.0005 19.3 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KKF96842.1 - 0.0035 16.8 0.3 0.0083 15.6 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKF96842.1 - 0.01 15.8 0.2 0.039 13.9 0.2 1.9 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 KKF96842.1 - 0.04 13.0 0.0 0.84 8.7 0.0 2.4 2 1 0 2 2 2 0 RmlD substrate binding domain DUF4604 PF15377.6 KKF96844.1 - 0.021 15.3 13.9 0.021 15.3 13.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) PBP1_TM PF14812.6 KKF96844.1 - 0.3 11.5 14.1 0.36 11.2 14.1 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GEN1_C PF18380.1 KKF96844.1 - 0.52 11.2 10.7 0.58 11.1 10.7 1.2 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain FAM176 PF14851.6 KKF96844.1 - 0.53 9.9 14.8 0.61 9.7 14.8 1.1 1 0 0 1 1 1 0 FAM176 family DUF2052 PF09747.9 KKF96844.1 - 0.81 9.8 20.1 0.85 9.7 20.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TFB6 PF17110.5 KKF96844.1 - 1.4 8.7 11.9 1.6 8.4 11.9 1.0 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 KKF96844.1 - 1.5 7.0 18.1 1.4 7.1 18.1 1.0 1 0 0 1 1 1 0 CDC45-like protein EIIBC-GUT_N PF03612.14 KKF96844.1 - 1.9 8.2 7.3 1.9 8.2 7.3 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CPSF100_C PF13299.6 KKF96844.1 - 2 8.6 12.1 2.1 8.5 12.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Sporozoite_P67 PF05642.11 KKF96844.1 - 2.3 6.2 11.2 2.3 6.2 11.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Merozoite_SPAM PF07133.11 KKF96844.1 - 2.3 8.2 30.7 2.4 8.1 30.7 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Paf1 PF03985.13 KKF96844.1 - 2.6 6.9 21.7 2.6 7.0 21.7 1.0 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.12 KKF96844.1 - 2.8 7.2 14.7 3 7.1 14.7 1.1 1 0 0 1 1 1 0 NOA36 protein RNA_pol_Rpc4 PF05132.14 KKF96844.1 - 3 8.3 11.6 3.3 8.1 11.6 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Cnd2 PF05786.14 KKF96844.1 - 3 6.4 17.5 3.1 6.3 17.5 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Vfa1 PF08432.10 KKF96844.1 - 3.7 7.8 16.4 4.3 7.6 16.4 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TFIIF_alpha PF05793.12 KKF96844.1 - 4.1 5.9 24.5 4 5.9 24.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4746 PF15928.5 KKF96844.1 - 4.2 6.7 17.2 4.8 6.5 17.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RPN2_C PF18004.1 KKF96844.1 - 4.4 7.2 21.5 5 7.0 21.5 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Tim54 PF11711.8 KKF96844.1 - 4.5 5.9 13.3 4.9 5.8 13.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.16 KKF96844.1 - 5 6.2 11.5 5.3 6.2 11.5 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_C37 PF05416.12 KKF96844.1 - 5.6 5.4 10.0 5.3 5.4 10.0 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF913 PF06025.12 KKF96844.1 - 6.1 5.7 10.2 6.1 5.7 10.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PI3K_1B_p101 PF10486.9 KKF96844.1 - 6.9 4.3 10.4 7.7 4.2 10.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GNAT_acetyltr_2 PF13718.6 KKF96844.1 - 7.6 5.9 7.1 7.9 5.8 7.1 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DDHD PF02862.17 KKF96844.1 - 8.1 6.5 7.0 8.1 6.5 7.0 1.0 1 0 0 1 1 1 0 DDHD domain AIF_C PF14721.6 KKF96844.1 - 8.1 6.8 8.0 8.9 6.7 8.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sec62 PF03839.16 KKF96844.1 - 8.5 5.8 9.0 9.2 5.7 9.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4366 PF14283.6 KKF96844.1 - 8.6 6.4 11.4 9.8 6.2 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RR_TM4-6 PF06459.12 KKF96844.1 - 9.3 6.0 18.1 9.1 6.0 18.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 tRNA_int_end_N2 PF12928.7 KKF96845.1 - 7.9e-17 61.2 0.0 1.8e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term DUF866 PF05907.13 KKF96846.1 - 1.9e-45 154.5 0.3 2.1e-45 154.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF4379 PF14311.6 KKF96846.1 - 0.086 13.2 1.7 0.21 12.0 1.7 1.8 1 1 0 1 1 1 0 Probable Zinc-ribbon domain GDPD PF03009.17 KKF96847.1 - 3e-58 197.6 0.0 3.9e-56 190.7 0.0 2.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KKF96847.1 - 1.3e-25 89.8 0.0 1.3e-08 35.3 0.0 4.8 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKF96847.1 - 7.4e-25 87.0 1.1 9.2e-06 26.1 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 KKF96847.1 - 2.8e-21 76.9 10.4 1.4e-11 45.0 0.1 3.9 2 1 2 4 4 4 3 SPX domain Ank_5 PF13857.6 KKF96847.1 - 1.9e-19 69.4 0.5 1.8e-11 44.0 0.1 5.6 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KKF96847.1 - 1.7e-15 56.7 1.0 0.0013 19.0 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KKF96847.1 - 1e-14 53.2 2.4 0.0044 17.4 0.0 7.3 8 0 0 8 8 8 3 Ankyrin repeat CstA PF02554.14 KKF96848.1 - 0.027 13.4 0.2 0.046 12.6 0.2 1.3 1 0 0 1 1 1 0 Carbon starvation protein CstA zf-C2H2 PF00096.26 KKF96849.1 - 1.7e-19 69.1 32.6 1.1e-05 25.6 0.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKF96849.1 - 4.4e-18 64.8 30.1 2e-06 27.9 0.7 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKF96849.1 - 2.8e-08 33.9 29.2 0.026 15.3 2.2 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKF96849.1 - 0.00087 19.5 3.7 1.2 9.6 0.7 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KKF96849.1 - 0.011 15.5 1.6 0.011 15.5 1.6 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-TRAF PF02176.18 KKF96849.1 - 0.036 14.8 2.3 0.036 14.8 2.3 3.3 1 1 2 3 3 3 0 TRAF-type zinc finger zf-met PF12874.7 KKF96849.1 - 0.4 11.1 11.2 0.3 11.5 0.6 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KKF96849.1 - 5.2 7.2 11.0 5.2 7.2 0.1 3.2 2 2 1 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 KKF96849.1 - 7.6 7.3 21.0 0.93 10.2 0.4 4.8 2 1 3 5 5 5 0 FOXP coiled-coil domain Peptidase_M41 PF01434.18 KKF96850.1 - 6.7e-56 189.2 0.1 1.6e-55 187.9 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KKF96850.1 - 4.2e-42 143.7 0.0 1.6e-41 141.8 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKF96850.1 - 5e-11 42.2 0.1 1e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KKF96850.1 - 6.9e-06 26.1 0.0 2.8e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKF96850.1 - 1.3e-05 25.6 0.3 0.00024 21.5 0.3 3.1 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KKF96850.1 - 3.6e-05 23.1 0.0 0.00011 21.5 0.0 1.8 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KKF96850.1 - 0.00062 20.1 0.1 0.029 14.7 0.1 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KKF96850.1 - 0.00068 19.4 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KKF96850.1 - 0.0045 17.1 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KKF96850.1 - 0.0053 16.3 1.3 0.78 9.3 0.3 2.8 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKF96850.1 - 0.01 15.6 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKF96850.1 - 0.022 14.1 0.3 0.047 13.1 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KKF96850.1 - 0.038 14.0 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKF96850.1 - 0.052 13.1 0.4 0.27 10.8 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_2 PF07724.14 KKF96850.1 - 0.055 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KKF96850.1 - 0.071 13.7 0.1 0.23 12.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KKF96850.1 - 0.11 12.8 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKF96850.1 - 0.16 11.9 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KKF96850.1 - 0.2 11.6 0.3 1.7 8.5 0.1 2.3 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KKF96850.1 - 0.42 9.9 2.4 0.5 9.6 0.4 2.1 2 1 1 3 3 3 0 Zeta toxin zf-ZPR1 PF03367.13 KKF96851.1 - 4.9e-114 377.5 0.2 6e-56 188.7 0.3 2.8 2 1 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 KKF96851.1 - 2.9 8.0 5.2 2.7 8.0 0.6 2.4 2 1 0 2 2 2 0 zinc-ribbons Metallophos PF00149.28 KKF96852.1 - 1.9e-32 113.4 0.1 3.4e-31 109.3 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKF96852.1 - 0.17 12.1 0.0 0.55 10.4 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Smg4_UPF3 PF03467.15 KKF96853.1 - 3.1e-34 118.5 0.0 3.1e-34 118.5 0.0 4.0 5 0 0 5 5 5 1 Smg-4/UPF3 family RRM_1 PF00076.22 KKF96853.1 - 3.7e-06 26.7 1.0 4.3e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANTAR PF03861.14 KKF96853.1 - 0.025 14.4 0.3 0.049 13.5 0.3 1.5 1 0 0 1 1 1 0 ANTAR domain Colicin_Pyocin PF01320.18 KKF96853.1 - 0.12 12.6 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein E1_dh PF00676.20 KKF96854.1 - 1.9e-110 368.5 0.1 2.5e-110 368.2 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KKF96854.1 - 0.0026 17.0 0.3 0.0069 15.6 0.1 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_ligase_A_M PF01068.21 KKF96855.1 - 2.3e-58 197.2 2.8 4.7e-47 160.3 0.1 2.6 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKF96855.1 - 6.5e-41 140.5 0.0 1.4e-40 139.4 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KKF96855.1 - 6e-29 100.6 0.9 4.8e-28 97.7 0.0 2.7 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KKF96855.1 - 2e-06 28.2 0.0 3.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 RNA ligase Voltage_CLC PF00654.20 KKF96856.1 - 1.8e-85 287.3 32.0 1.8e-85 287.3 32.0 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KKF96856.1 - 0.038 14.5 0.0 3.5 8.2 0.0 2.7 2 0 0 2 2 2 0 CBS domain LacI PF00356.21 KKF96856.1 - 0.44 10.4 1.5 1.3 8.8 1.5 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Neurochondrin PF05536.11 KKF96857.1 - 1.1e-73 248.7 0.3 1.4e-73 248.2 0.3 1.2 1 0 0 1 1 1 1 Neurochondrin Sec7_N PF12783.7 KKF96857.1 - 0.11 12.3 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ATP-synt_D PF01813.17 KKF96858.1 - 0.072 12.9 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 ATP synthase subunit D Methyltransf_23 PF13489.6 KKF96859.1 - 1.9e-23 83.1 0.2 4.4e-23 81.9 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF96859.1 - 1.6e-11 44.8 0.0 7.5e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF96859.1 - 2.3e-11 43.7 0.0 7.8e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KKF96859.1 - 3.3e-08 34.1 0.0 8.8e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF96859.1 - 9.3e-07 29.5 0.0 6.6e-06 26.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KKF96859.1 - 0.00022 20.6 0.0 0.00043 19.7 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KKF96859.1 - 0.00062 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KKF96859.1 - 0.0016 18.5 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 KKF96859.1 - 0.002 17.6 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KKF96859.1 - 0.016 14.6 0.0 0.048 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KKF96859.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KKF96859.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KKF96859.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Med3 PF11593.8 KKF96859.1 - 1.9 7.6 18.2 2.5 7.2 18.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ras PF00071.22 KKF96860.1 - 2.9e-52 176.5 0.0 3.4e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF96860.1 - 3.1e-19 69.4 0.0 4.2e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF96860.1 - 3.2e-05 23.5 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF2511 PF10709.9 KKF96860.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2511) tRNA-synt_2 PF00152.20 KKF96861.1 - 2.8e-70 236.9 0.0 4e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKF96861.1 - 2.2e-08 34.0 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ribonuc_L-PSP PF01042.21 KKF96862.1 - 5e-20 71.7 0.0 6.2e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP RRM_1 PF00076.22 KKF96863.1 - 4.2e-35 119.4 0.2 2.5e-10 40.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKF96863.1 - 5.5e-16 58.2 0.0 0.0043 16.9 0.0 4.4 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 KKF96863.1 - 8.9e-09 34.9 5.5 8.9e-09 34.9 5.5 2.6 2 0 0 2 2 2 1 Putative RRM domain RRM_7 PF16367.5 KKF96863.1 - 9.9e-06 25.6 0.0 0.021 14.9 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif DUF4523 PF15023.6 KKF96863.1 - 1.1e-05 25.3 0.0 0.11 12.3 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 KKF96863.1 - 2.2e-05 24.4 0.3 0.32 11.1 0.2 2.9 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.6 KKF96863.1 - 0.0063 16.5 0.1 3.4 7.7 0.1 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KKF96863.1 - 0.01 15.7 0.0 0.78 9.5 0.0 3.6 2 1 2 4 4 4 0 Rrp7 RRM-like N-terminal domain RNA_bind PF08675.11 KKF96863.1 - 0.012 15.6 0.9 1 9.4 0.0 3.1 3 1 1 4 4 4 0 RNA binding domain MIF PF01187.18 KKF96864.1 - 2.7e-10 40.5 0.0 5.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Kelch_5 PF13854.6 KKF96865.1 - 3.9e-10 39.5 11.2 1.2e-07 31.5 0.3 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 KKF96865.1 - 8.6e-05 22.5 9.0 0.036 14.1 0.0 5.1 5 2 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KKF96865.1 - 8.9e-05 22.6 11.9 0.002 18.4 0.3 5.0 4 1 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 KKF96865.1 - 0.00079 19.7 0.2 0.00079 19.7 0.2 4.9 5 1 1 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.15 KKF96865.1 - 0.0063 16.5 9.1 0.032 14.2 0.2 4.8 6 0 0 6 6 6 1 Kelch motif SYF2 PF08231.12 KKF96866.1 - 2e-53 181.1 13.1 2e-53 181.1 13.1 1.8 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.14 KKF96866.1 - 4.9 7.3 10.8 0.48 10.6 0.5 3.1 2 1 0 3 3 3 0 ARD/ARD' family Pannexin_like PF12534.8 KKF96866.1 - 9.5 5.2 5.8 7.4 5.6 4.2 1.5 1 1 0 1 1 1 0 Pannexin-like TM region of LRRC8 Epimerase PF01370.21 KKF96867.1 - 6.6e-07 29.0 0.0 3.8e-06 26.5 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKF96867.1 - 6.5e-05 22.9 0.0 0.00062 19.7 0.0 2.4 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKF96867.1 - 0.00017 20.9 0.0 0.0041 16.3 0.0 2.6 3 1 0 3 3 3 1 Male sterility protein RmlD_sub_bind PF04321.17 KKF96867.1 - 0.0007 18.8 0.0 0.088 11.9 0.0 2.5 2 1 0 2 2 2 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KKF96867.1 - 0.004 16.6 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKF96867.1 - 0.027 13.5 0.0 0.058 12.4 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family YEATS PF03366.16 KKF96868.1 - 1e-28 99.1 0.3 1.5e-28 98.6 0.3 1.2 1 0 0 1 1 1 1 YEATS family AWPM-19 PF05512.11 KKF96868.1 - 0.14 12.4 2.1 0.27 11.4 2.1 1.4 1 0 0 1 1 1 0 AWPM-19-like family CCDC-167 PF15188.6 KKF96868.1 - 0.6 10.5 3.1 1.2 9.5 3.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ins_P5_2-kin PF06090.12 KKF96870.1 - 9.9e-35 120.5 0.1 8.6e-33 114.2 0.1 2.3 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase LRR_8 PF13855.6 KKF96872.1 - 0.34 10.7 3.0 4.4 7.2 0.1 3.3 3 0 0 3 3 3 0 Leucine rich repeat Glycogen_syn PF05693.13 KKF96874.1 - 0 1168.0 0.0 0 1167.7 0.0 1.1 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KKF96874.1 - 2.4e-05 23.9 0.0 0.0044 16.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKF96874.1 - 4.3e-05 23.6 0.4 9.9e-05 22.4 0.4 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KKF96874.1 - 7.8e-05 23.1 0.0 0.071 13.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KKF96874.1 - 0.00012 21.9 0.5 0.00022 21.0 0.0 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 KKF96874.1 - 0.00046 20.7 0.0 0.00099 19.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF3684 PF12449.8 KKF96875.1 - 0 1358.1 0.0 0 1357.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KKF96875.1 - 0.0002 21.2 0.0 0.00059 19.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PIEZO PF15917.5 KKF96875.1 - 0.03 13.8 3.1 0.068 12.6 3.1 1.5 1 0 0 1 1 1 0 Piezo Reprolysin_5 PF13688.6 KKF96875.1 - 0.072 13.2 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 PRKCSH_1 PF13015.6 KKF96875.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein RBM39linker PF15519.6 KKF96875.1 - 6.9 7.8 8.8 0.6 11.2 1.3 3.0 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Hid1 PF12722.7 KKF96877.1 - 3.8e-192 640.6 0.0 3.6e-90 303.3 0.0 3.0 1 1 2 3 3 3 3 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KKF96877.1 - 3e-64 217.5 0.0 3.2e-32 111.8 0.0 3.1 1 1 2 3 3 3 3 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.11 KKF96877.1 - 5.8e-22 78.1 0.0 1.3e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore complex component DUF913 PF06025.12 KKF96877.1 - 0.0054 15.8 0.3 0.0093 15.0 0.3 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF3246 PF11596.8 KKF96877.1 - 4.1 6.8 10.2 7.6 5.9 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) PAC3 PF10178.9 KKF96878.1 - 0.00011 22.3 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 HA2 PF04408.23 KKF96879.1 - 1.6e-26 92.7 3.6 2.2e-26 92.3 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKF96879.1 - 2.5e-11 43.9 0.0 1.8e-10 41.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KKF96879.1 - 2.4e-10 40.6 0.0 5.7e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KKF96879.1 - 7.4e-09 35.6 0.0 1.9e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KKF96879.1 - 0.0015 18.9 0.0 0.0038 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKF96879.1 - 0.0033 17.7 0.0 0.02 15.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKF96879.1 - 0.012 14.7 0.0 0.029 13.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KKF96879.1 - 0.023 14.1 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 KKF96879.1 - 0.034 13.9 0.1 0.093 12.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF927 PF06048.11 KKF96879.1 - 0.04 13.5 0.2 0.08 12.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Scytalone_dh PF02982.14 KKF96880.1 - 2e-79 265.0 3.2 2.9e-79 264.4 3.2 1.2 1 0 0 1 1 1 1 Scytalone dehydratase Med6 PF04934.14 KKF96880.1 - 1.1e-37 128.8 0.1 1.6e-37 128.3 0.1 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component SnoaL_4 PF13577.6 KKF96880.1 - 0.0047 17.1 4.1 0.012 15.7 4.1 1.7 1 1 0 1 1 1 1 SnoaL-like domain Ribosomal_L27_C PF18471.1 KKF96881.1 - 0.0094 15.4 3.2 0.016 14.6 3.2 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Trypan_PARP PF05887.11 KKF96882.1 - 0.93 9.5 7.6 2.1 8.3 7.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Annexin PF00191.20 KKF96883.1 - 8e-70 230.9 7.7 4.8e-18 65.0 0.2 4.2 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 KKF96883.1 - 0.061 13.8 1.3 5.6 7.5 0.0 3.2 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 NuA4 PF09340.10 KKF96884.1 - 5.7e-24 83.8 0.2 5.7e-24 83.8 0.2 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF2716 PF10898.8 KKF96885.1 - 0.12 12.8 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) JAB PF01398.21 KKF96886.1 - 6.4e-11 42.3 0.0 3.7e-10 39.8 0.0 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease EpmC PF04315.12 KKF96886.1 - 0.027 14.2 0.1 0.057 13.1 0.1 1.5 1 0 0 1 1 1 0 Elongation factor P hydroxylase AdoHcyase PF05221.17 KKF96887.1 - 1.5e-130 434.7 0.0 1.5e-74 250.9 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KKF96887.1 - 8.1e-82 273.1 2.8 1.3e-81 272.4 2.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KKF96887.1 - 1.4e-05 24.5 0.7 2.7e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KKF96887.1 - 0.036 14.3 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AAA_31 PF13614.6 KKF96887.1 - 0.076 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Urocanase PF01175.18 KKF96887.1 - 0.12 12.0 0.9 0.2 11.3 0.9 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain 2-Hacid_dh_C PF02826.19 KKF96888.1 - 4.1e-57 192.4 0.0 7.8e-57 191.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKF96888.1 - 2.3e-18 66.1 0.0 2.9e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKF96888.1 - 4.7e-06 26.9 0.1 8e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KKF96888.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Med1 PF10744.9 KKF96888.1 - 0.17 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 DUF2457 PF10446.9 KKF96889.1 - 1.7 7.7 10.4 2.2 7.3 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PAT1 PF09770.9 KKF96889.1 - 2.6 6.2 10.5 3.1 5.9 10.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 KKF96889.1 - 4.3 7.2 13.4 5.9 6.8 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NARP1 PF12569.8 KKF96890.1 - 2.9e-177 590.7 23.3 3.4e-176 587.2 18.4 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KKF96890.1 - 1.7e-16 60.4 25.7 0.0033 17.9 0.1 9.1 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKF96890.1 - 5.5e-14 51.7 25.0 0.02 15.7 0.0 10.9 10 2 3 13 13 10 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF96890.1 - 8.6e-14 51.5 15.1 7.9e-06 26.0 0.9 5.5 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KKF96890.1 - 9.2e-14 50.4 39.7 0.0015 18.5 0.2 10.8 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 KKF96890.1 - 1.9e-12 47.6 13.0 0.086 13.5 0.0 9.0 7 3 2 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 KKF96890.1 - 5.3e-12 45.7 0.0 0.02 15.0 0.1 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKF96890.1 - 1.1e-10 41.1 4.6 2.3e-05 24.0 0.0 6.2 6 0 0 6 6 6 1 TPR repeat TPR_8 PF13181.6 KKF96890.1 - 8.5e-10 38.1 32.9 0.0026 17.8 0.1 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KKF96890.1 - 4.7e-09 36.0 21.0 0.14 12.6 0.0 10.0 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 KKF96890.1 - 8.6e-09 34.9 33.4 7.9e-05 22.3 0.3 9.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 KKF96890.1 - 1.1e-05 25.7 17.0 0.21 12.3 0.1 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKF96890.1 - 0.00014 22.1 22.9 0.069 13.4 0.2 6.4 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 KKF96890.1 - 0.00038 19.7 11.0 0.0049 16.1 0.6 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KKF96890.1 - 0.002 18.0 9.7 1.1 9.3 0.3 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat PPR PF01535.20 KKF96890.1 - 0.0077 16.4 4.1 16 6.0 0.0 6.8 8 0 0 8 8 7 0 PPR repeat TPR_MalT PF17874.1 KKF96890.1 - 0.01 15.3 4.7 0.11 11.9 0.1 3.6 4 0 0 4 4 4 1 MalT-like TPR region TPR_7 PF13176.6 KKF96890.1 - 0.043 13.8 8.2 13 6.1 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKF96890.1 - 0.27 12.0 7.3 0.29 11.9 0.4 4.5 7 0 0 7 7 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKF96890.1 - 3 8.0 12.9 34 4.6 1.4 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat GTA_holin_3TM PF11351.8 KKF96890.1 - 5.5 7.5 5.9 4.9 7.7 3.6 2.1 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Thiolase_N PF00108.23 KKF96891.1 - 8.2e-66 222.0 1.4 1.2e-65 221.4 1.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKF96891.1 - 7.3e-38 129.0 1.6 7.3e-38 129.0 1.6 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKF96891.1 - 0.0013 18.4 4.3 0.0054 16.3 2.5 2.6 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KKF96891.1 - 0.0066 16.3 3.3 0.11 12.4 0.7 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SARAF PF06682.12 KKF96892.1 - 1.9e-77 261.1 8.8 5e-76 256.5 8.8 2.2 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis FixQ PF05545.11 KKF96892.1 - 0.41 10.6 1.7 0.78 9.8 1.7 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ BRE1 PF08647.11 KKF96893.1 - 5.5e-22 77.6 6.6 5.5e-22 77.6 6.6 6.7 3 2 3 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KKF96893.1 - 5e-09 35.9 7.4 7.8e-09 35.3 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKF96893.1 - 2.9e-08 33.4 9.8 5.5e-08 32.5 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKF96893.1 - 3e-08 33.5 5.4 5.6e-08 32.7 5.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KKF96893.1 - 4.6e-08 32.8 10.1 8.4e-08 32.0 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKF96893.1 - 7.8e-08 32.1 6.6 1.3e-07 31.3 6.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KKF96893.1 - 1.7e-06 28.3 8.2 3e-06 27.5 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KKF96893.1 - 1.8e-05 24.6 9.9 3.4e-05 23.7 9.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FAM184 PF15665.5 KKF96893.1 - 0.004 17.0 17.0 0.004 17.0 17.0 4.9 1 1 2 4 4 2 1 Family with sequence similarity 184, A and B zf-RING_6 PF14835.6 KKF96893.1 - 0.018 14.9 2.7 0.04 13.8 2.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KKF96893.1 - 0.021 15.0 6.0 0.04 14.1 6.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KKF96893.1 - 0.032 14.0 7.3 0.065 13.0 7.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TSC22 PF01166.18 KKF96893.1 - 0.055 13.8 18.7 0.36 11.2 0.2 5.7 5 1 1 6 6 6 0 TSC-22/dip/bun family zf-UDP PF14569.6 KKF96893.1 - 0.089 12.9 3.4 0.29 11.3 3.4 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-rbx1 PF12678.7 KKF96893.1 - 0.3 11.4 7.0 1.1 9.6 7.0 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KKF96893.1 - 0.3 11.2 5.9 0.87 9.8 5.9 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 KKF96893.1 - 0.37 10.9 5.6 0.92 9.6 5.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) APC_N_CC PF16689.5 KKF96893.1 - 0.5 10.5 10.9 2.4 8.3 0.2 5.4 5 0 0 5 5 4 0 Coiled-coil N-terminus of APC, dimerisation domain FYVE PF01363.21 KKF96893.1 - 1 9.6 10.1 12 6.1 9.7 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-RING_11 PF17123.5 KKF96893.1 - 2.1 8.2 4.3 4.9 7.0 4.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger DUF724 PF05266.14 KKF96893.1 - 5.7 6.7 56.2 0.08 12.8 4.6 5.2 1 1 3 5 5 5 0 Protein of unknown function (DUF724) Myb_DNA-bind_7 PF15963.5 KKF96894.1 - 1.5e-25 88.9 0.1 1.5e-25 88.9 0.1 1.8 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KKF96894.1 - 1.9e-07 31.1 0.0 4.7e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKF96894.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF678 PF05077.12 KKF96894.1 - 0.041 14.0 0.9 0.14 12.3 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF678) XPC-binding PF09280.11 KKF96895.1 - 4e-23 80.9 14.9 8.1e-23 79.9 12.8 2.2 2 0 0 2 2 2 1 XPC-binding domain UBA PF00627.31 KKF96895.1 - 3e-21 74.9 9.6 2.8e-11 43.1 3.1 2.8 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KKF96895.1 - 4.8e-19 67.9 0.2 8.8e-19 67.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KKF96895.1 - 1.5e-07 31.1 0.9 3.6e-07 29.9 0.9 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KKF96895.1 - 6.6e-05 23.2 0.1 0.00014 22.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 KKF96895.1 - 0.01 16.4 0.1 0.023 15.2 0.0 1.6 2 0 0 2 2 1 0 DUF2407 ubiquitin-like domain MCM_N PF14551.6 KKF96895.1 - 0.013 16.1 0.4 0.083 13.5 0.1 2.2 2 0 0 2 2 2 0 MCM N-terminal domain Rad60-SLD_2 PF13881.6 KKF96895.1 - 0.042 13.9 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rh5 PF18515.1 KKF96895.1 - 0.078 12.3 0.0 5.7 6.2 0.1 2.1 2 0 0 2 2 2 0 Rh5 coiled-coil domain Importin_rep_3 PF18806.1 KKF96895.1 - 0.17 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Importin 13 repeat Ubiquitin_4 PF18036.1 KKF96895.1 - 0.6 10.2 3.4 6.3 6.9 0.1 2.8 2 1 1 3 3 3 0 Ubiquitin-like domain DHHA1 PF02272.19 KKF96895.1 - 2.5 8.5 8.7 3.5 8.0 4.4 2.5 2 0 0 2 2 2 0 DHHA1 domain MFS_1 PF07690.16 KKF96896.1 - 6.6e-38 130.5 43.9 6.6e-38 130.5 43.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4328 PF14219.6 KKF96896.1 - 2.2 7.8 7.2 0.1 12.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) DUF3817 PF12823.7 KKF96896.1 - 5.4 7.9 11.5 0.33 11.8 3.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) Methyltr_RsmB-F PF01189.17 KKF96897.1 - 6.7e-14 52.0 0.0 4.2e-09 36.3 0.0 2.6 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DUF1996 PF09362.10 KKF96898.1 - 2.2e-62 211.1 0.2 2.9e-62 210.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Serglycin PF04360.12 KKF96898.1 - 0.25 11.3 3.2 0.74 9.7 3.2 1.8 1 0 0 1 1 1 0 Serglycin Peptidase_M24 PF00557.24 KKF96899.1 - 4.4e-56 189.9 0.2 6.6e-56 189.3 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KKF96899.1 - 5.2e-23 81.1 0.0 9.7e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Methyltransf_16 PF10294.9 KKF96901.1 - 1.6e-09 37.7 0.0 6e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_11 PF08241.12 KKF96901.1 - 0.015 15.9 0.0 0.11 13.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 KKF96901.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 KKF96901.1 - 0.093 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Surp PF01805.20 KKF96902.1 - 1.2e-08 34.8 0.0 2.2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Surp module TBP PF00352.21 KKF96903.1 - 1.1e-67 224.0 0.1 6e-33 112.7 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KKF96903.1 - 8.9e-05 22.5 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KKF96903.1 - 0.1 12.4 0.2 0.59 10.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) SUR7 PF06687.12 KKF96904.1 - 1.1e-26 93.8 4.0 1.3e-26 93.6 4.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family NVEALA PF14055.6 KKF96904.1 - 0.025 14.6 1.0 1.8 8.6 0.3 2.9 2 0 0 2 2 2 0 NVEALA protein Gln-synt_C PF00120.24 KKF96904.1 - 0.17 10.9 0.0 0.99 8.3 0.0 1.9 2 0 0 2 2 2 0 Glutamine synthetase, catalytic domain RRF PF01765.19 KKF96905.1 - 1.5e-25 90.0 0.1 2.7e-25 89.2 0.1 1.3 1 0 0 1 1 1 1 Ribosome recycling factor WD40 PF00400.32 KKF96905.1 - 1.7e-19 69.7 9.1 6.7e-06 26.8 0.0 9.8 10 0 0 10 10 10 3 WD domain, G-beta repeat DUF751 PF05421.11 KKF96905.1 - 0.9 10.3 3.3 29 5.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF751) Aldedh PF00171.22 KKF96906.1 - 1.5e-134 449.0 1.4 2e-134 448.6 1.4 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HATPase_c PF02518.26 KKF96907.1 - 2.4e-22 79.6 0.0 7.3e-22 78.0 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKF96907.1 - 7.8e-19 67.9 0.0 1.8e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KKF96907.1 - 1.8e-07 31.1 0.2 1.8e-07 31.1 0.2 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KKF96907.1 - 7.3e-07 29.4 0.1 0.041 14.1 0.0 4.0 3 1 0 3 3 3 2 PAS fold PAS PF00989.25 KKF96907.1 - 0.0013 18.8 0.0 0.17 11.9 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 KKF96907.1 - 0.03 14.4 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 PAS domain PH_6 PF15406.6 KKF96908.1 - 2.1e-34 118.1 2.6 2.1e-34 118.1 2.6 3.7 3 1 1 5 5 5 1 Pleckstrin homology domain PH PF00169.29 KKF96908.1 - 0.0034 17.9 0.1 0.012 16.1 0.0 2.1 2 1 0 2 2 2 1 PH domain PH_13 PF16652.5 KKF96908.1 - 0.028 14.2 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain tRNA-synt_2 PF00152.20 KKF96909.1 - 8e-68 228.8 0.0 6.7e-54 183.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KKF96909.1 - 1.4e-05 24.7 0.0 0.0044 16.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Rib_5-P_isom_A PF06026.14 KKF96910.1 - 8.4e-46 155.7 0.0 1.2e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Ras PF00071.22 KKF96911.1 - 5.5e-60 201.6 0.8 7.2e-60 201.3 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF96911.1 - 8.5e-38 129.3 0.2 1.5e-37 128.5 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF96911.1 - 3.6e-18 65.6 0.5 3.6e-18 65.6 0.5 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 KKF96911.1 - 1.1e-06 28.2 0.1 1.6e-06 27.7 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KKF96911.1 - 1.3e-06 28.1 0.3 1.3e-05 24.8 0.4 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKF96911.1 - 1.5e-05 25.1 0.1 2.6e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKF96911.1 - 1.8e-05 24.2 0.6 2.3e-05 23.9 0.6 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKF96911.1 - 0.00025 21.0 0.7 0.14 12.1 0.3 2.3 2 1 0 2 2 2 2 RsgA GTPase FlgH PF02107.16 KKF96911.1 - 0.024 14.3 1.3 0.058 13.0 1.3 1.6 1 1 0 1 1 1 0 Flagellar L-ring protein TIR_2 PF13676.6 KKF96911.1 - 0.079 13.6 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 TIR domain TetR_C_16 PF17920.1 KKF96911.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Nop53 PF07767.11 KKF96912.1 - 9.5e-105 351.2 31.3 1.1e-104 351.0 31.3 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Hamartin PF04388.12 KKF96912.1 - 0.28 9.8 6.7 0.41 9.3 6.7 1.2 1 0 0 1 1 1 0 Hamartin protein GREB1 PF15782.5 KKF96912.1 - 5.3 4.0 9.7 6.9 3.6 9.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LsmAD PF06741.13 KKF96912.1 - 6.3 7.4 17.7 2.3 8.9 2.3 3.2 2 1 1 3 3 3 0 LsmAD domain PRK PF00485.18 KKF96913.1 - 4.9e-60 202.6 0.0 1e-59 201.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Pyr_redox_2 PF07992.14 KKF96913.1 - 7.7e-41 140.2 0.0 1.1e-40 139.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UPRTase PF14681.6 KKF96913.1 - 1.9e-34 119.0 0.0 3.5e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pyr_redox PF00070.27 KKF96913.1 - 3.8e-12 46.6 0.0 7.8e-10 39.2 0.0 3.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KKF96913.1 - 1.2e-07 30.8 0.3 4.5e-07 29.0 0.3 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KKF96913.1 - 3.6e-06 26.5 0.5 1.2e-05 24.8 0.5 1.9 1 0 0 1 1 1 1 EF-hand domain AAA_18 PF13238.6 KKF96913.1 - 8.6e-06 26.3 0.0 0.00017 22.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 KKF96913.1 - 2.1e-05 24.5 0.0 3.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein EF-hand_7 PF13499.6 KKF96913.1 - 9.8e-05 22.7 0.1 0.00041 20.7 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KKF96913.1 - 0.00011 21.5 0.9 0.00023 20.5 0.9 1.5 1 0 0 1 1 1 1 EF hand AAA_17 PF13207.6 KKF96913.1 - 0.00028 21.3 0.1 0.44 11.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKF96913.1 - 0.0016 18.6 0.0 0.0052 17.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 KKF96913.1 - 0.0053 17.3 1.0 0.019 15.4 0.1 2.4 2 0 0 2 2 2 1 ABC transporter DUF87 PF01935.17 KKF96913.1 - 0.0072 16.5 0.1 0.27 11.3 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain NB-ARC PF00931.22 KKF96913.1 - 0.0087 15.3 0.1 0.035 13.3 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.12 KKF96913.1 - 0.0088 15.3 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 KKF96913.1 - 0.02 14.6 0.3 0.16 11.8 0.3 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sec5 PF15469.6 KKF96913.1 - 0.064 13.1 0.3 2.2 8.0 0.1 2.6 2 0 0 2 2 2 0 Exocyst complex component Sec5 dNK PF01712.19 KKF96913.1 - 0.068 13.0 0.4 12 5.7 0.0 3.2 3 0 0 3 3 3 0 Deoxynucleoside kinase EF-hand_8 PF13833.6 KKF96913.1 - 0.074 12.9 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair MscS_porin PF12795.7 KKF96913.1 - 0.08 12.5 1.7 0.15 11.6 1.7 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain AAA_22 PF13401.6 KKF96913.1 - 0.11 12.8 0.1 3.2 8.0 0.0 3.2 4 0 0 4 4 3 0 AAA domain Cytidylate_kin2 PF13189.6 KKF96913.1 - 0.13 12.4 0.1 41 4.3 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase-like family ETC_C1_NDUFA4 PF04800.12 KKF96914.1 - 1.7e-36 124.3 1.8 2.7e-36 123.7 1.8 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.9 KKF96915.1 - 6.9e-34 116.2 0.2 8.4e-34 115.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi MCM PF00493.23 KKF96917.1 - 1.3e-102 341.7 0.3 2.3e-102 340.9 0.3 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKF96917.1 - 6e-39 132.8 0.2 1.2e-38 131.8 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KKF96917.1 - 1.5e-27 95.9 0.2 5.2e-27 94.2 0.0 2.0 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KKF96917.1 - 1.8e-24 86.0 0.4 5.7e-24 84.4 0.4 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKF96917.1 - 2.3e-14 53.9 0.0 6.5e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKF96917.1 - 1.4e-06 27.8 0.0 4.2e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KKF96917.1 - 0.00076 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKF96917.1 - 0.0036 17.0 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KKF96917.1 - 0.045 13.8 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Aminotran_1_2 PF00155.21 KKF96918.1 - 1.4e-12 47.5 0.0 5.2e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Glyco_hydro_125 PF06824.11 KKF96919.1 - 2.6e-178 593.2 0.0 3.7e-178 592.7 0.0 1.2 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) MOZ_SAS PF01853.18 KKF96919.1 - 2.4e-62 209.8 1.0 3.7e-62 209.2 1.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.7 KKF96919.1 - 0.00019 21.8 0.0 0.00049 20.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKF96919.1 - 0.0042 17.3 0.0 0.0094 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Snf7 PF03357.21 KKF96920.1 - 2.3e-16 59.9 14.1 3.6e-16 59.2 13.8 1.4 1 1 0 1 1 1 1 Snf7 FlaC_arch PF05377.11 KKF96920.1 - 0.11 12.9 0.3 0.11 12.9 0.3 3.3 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) Not3 PF04065.15 KKF96920.1 - 0.13 11.7 10.5 0.011 15.1 3.9 2.1 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component HAUS-augmin3 PF14932.6 KKF96920.1 - 0.15 11.6 16.9 0.012 15.2 6.8 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 MIP-T3_C PF17749.1 KKF96920.1 - 0.26 11.3 10.5 4 7.4 3.4 3.3 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Sigma70_ner PF04546.13 KKF96920.1 - 6.4 6.6 12.2 0.24 11.3 1.9 2.7 2 1 0 3 3 3 0 Sigma-70, non-essential region Bud13 PF09736.9 KKF96921.1 - 6.1e-51 172.6 12.1 6.1e-51 172.6 12.1 2.9 2 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex SOBP PF15279.6 KKF96921.1 - 0.63 10.6 5.4 0.99 10.0 5.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein SPATIAL PF15256.6 KKF96921.1 - 4.9 7.4 9.3 2.1 8.6 5.5 2.1 1 1 1 2 2 2 0 SPATIAL GREB1 PF15782.5 KKF96922.1 - 1.3 6.0 10.4 2.1 5.4 10.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAP_assoc PF03828.19 KKF96923.1 - 1.4e-17 63.7 0.1 2.6e-11 43.5 0.0 2.8 2 0 0 2 2 2 2 Cid1 family poly A polymerase DUF3458_C PF17432.2 KKF96923.1 - 0.013 14.9 0.0 0.086 12.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3458_C) ARM repeats Patatin PF01734.22 KKF96924.1 - 3.2e-06 27.5 0.0 0.00074 19.8 0.0 2.5 1 1 0 2 2 2 2 Patatin-like phospholipase AAA_16 PF13191.6 KKF96924.1 - 0.014 15.8 0.1 0.11 12.9 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KKF96924.1 - 0.089 12.0 0.0 0.25 10.5 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Glyco_hydro_53 PF07745.13 KKF96925.1 - 2.6e-101 339.0 0.1 3e-101 338.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Peptidase_C48 PF02902.19 KKF96926.1 - 6.7e-13 49.0 0.1 2.4e-12 47.2 0.1 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SLX9 PF15341.6 KKF96927.1 - 7.3e-35 120.2 8.4 9.1e-35 119.9 8.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Pam17 PF08566.10 KKF96928.1 - 2.9e-56 189.8 0.0 4.5e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Baculo_PEP_C PF04513.12 KKF96929.1 - 0.021 14.9 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_N PF02465.18 KKF96929.1 - 0.024 15.3 0.1 0.028 15.1 0.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus HBM PF16591.5 KKF96929.1 - 0.032 13.6 0.1 0.032 13.6 0.1 1.1 1 0 0 1 1 1 0 Helical bimodular sensor domain NAD_Gly3P_dh_N PF01210.23 KKF96930.1 - 2e-44 151.3 0.1 8.2e-44 149.3 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KKF96930.1 - 1.8e-42 145.0 0.3 2.8e-42 144.4 0.3 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NUC130_3NT PF08158.12 KKF96930.1 - 0.081 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 NUC130/3NT domain HTH_ParB PF17762.1 KKF96930.1 - 0.21 11.4 0.3 1.6 8.6 0.0 2.4 3 0 0 3 3 3 0 HTH domain found in ParB protein hDGE_amylase PF14701.6 KKF96931.1 - 1e-176 588.3 0.0 1.4e-176 588.0 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KKF96931.1 - 3.1e-119 398.3 0.0 6.6e-119 397.3 0.0 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KKF96931.1 - 6.9e-40 137.3 0.4 2.3e-30 106.1 0.0 2.8 1 1 1 2 2 2 2 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KKF96931.1 - 6.7e-09 35.8 0.1 1.9e-08 34.3 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KKF96931.1 - 0.068 12.7 0.0 0.88 9.1 0.0 2.1 2 0 0 2 2 2 0 Alpha amylase, catalytic domain Peptidase_M1 PF01433.20 KKF96932.1 - 4.5e-46 157.2 0.5 7.3e-46 156.5 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KKF96932.1 - 1.5e-38 131.3 0.0 3.3e-38 130.3 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KKF96932.1 - 6.9e-30 104.6 0.0 1.2e-29 103.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KKF96932.1 - 0.056 13.1 0.3 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 KKF96932.1 - 0.37 11.2 3.0 4.3 7.8 1.6 2.7 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Jacalin PF01419.17 KKF96934.1 - 2e-05 24.5 0.1 3.7e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Snf7 PF03357.21 KKF96935.1 - 9e-31 106.8 19.8 9e-31 106.8 19.8 2.0 1 1 1 2 2 2 1 Snf7 Prefoldin_2 PF01920.20 KKF96935.1 - 0.25 11.3 18.8 0.1 12.5 7.1 2.8 3 1 0 3 3 3 0 Prefoldin subunit DUF3138 PF11336.8 KKF96935.1 - 0.54 8.8 13.4 0.064 11.9 7.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Fmp27_WPPW PF10359.9 KKF96935.1 - 0.76 8.6 9.6 0.95 8.2 9.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4795 PF16043.5 KKF96935.1 - 1.2 8.7 19.6 0.18 11.4 12.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) V_ATPase_I PF01496.19 KKF96935.1 - 3 5.7 8.2 3.6 5.4 8.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PRELI PF04707.14 KKF96938.1 - 9.1e-19 67.8 0.1 5.8e-16 58.7 0.0 2.1 1 1 1 2 2 2 2 PRELI-like family PCRF PF03462.18 KKF96939.1 - 2.8e-46 157.8 1.2 2.9e-46 157.8 0.1 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KKF96939.1 - 8.9e-33 112.7 1.5 8.9e-33 112.7 1.5 1.7 2 0 0 2 2 2 1 RF-1 domain MIR PF02815.19 KKF96939.1 - 0.054 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 MIR domain Use1 PF09753.9 KKF96940.1 - 2.7 7.7 11.9 5 6.8 11.9 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 Ank_5 PF13857.6 KKF96942.1 - 5.5e-15 55.2 0.4 1.2e-05 25.5 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKF96942.1 - 7.5e-13 48.9 0.1 5.8e-05 23.6 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKF96942.1 - 1.4e-12 47.8 0.5 3.3e-06 27.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KKF96942.1 - 7.2e-10 38.9 0.0 0.0013 19.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KKF96942.1 - 3.7e-09 36.1 0.0 0.0021 18.4 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KKF96942.1 - 1.1e-05 25.2 0.4 0.0001 22.1 0.4 2.4 1 1 0 1 1 1 1 KilA-N domain RapH_N PF18801.1 KKF96942.1 - 0.01 15.9 0.9 0.84 9.8 0.1 3.0 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal Terminase_2 PF03592.16 KKF96942.1 - 1.2 9.6 9.0 1.6 9.2 7.8 1.8 2 0 0 2 2 2 0 Terminase small subunit DUF445 PF04286.12 KKF96942.1 - 3.5 7.3 11.8 5.3 6.7 10.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF445) YpjP PF14005.6 KKF96942.1 - 3.7 7.6 5.2 8 6.5 0.2 3.1 2 1 2 4 4 4 0 YpjP-like protein Lactamase_B PF00753.27 KKF96943.1 - 1.3e-09 38.4 0.0 2.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKF96943.1 - 4.4e-07 29.6 0.0 0.0088 15.6 0.0 2.3 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Shikimate_dh_N PF08501.11 KKF96943.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain NAPRTase PF04095.16 KKF96944.1 - 1.6e-57 194.9 0.1 6.4e-31 107.8 0.4 2.1 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KKF96944.1 - 7.6e-34 116.8 0.1 1.7e-33 115.6 0.1 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Aldo_ket_red PF00248.21 KKF96945.1 - 3.5e-51 174.1 0.0 4e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3937 PF13073.6 KKF96945.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3937) EamA PF00892.20 KKF96946.1 - 4.4e-08 33.4 27.3 3.3e-06 27.3 1.7 2.6 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 KKF96946.1 - 0.0027 16.7 2.6 0.0027 16.7 2.6 2.6 2 1 0 2 2 2 2 Ceramide synthase regulator SLC35F PF06027.12 KKF96946.1 - 0.0083 15.7 4.0 0.012 15.1 2.9 1.8 1 1 0 1 1 1 1 Solute carrier family 35 Reo_sigmaC PF04582.12 KKF96946.1 - 0.095 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein C-terminal domain Nuc_sug_transp PF04142.15 KKF96946.1 - 0.16 11.1 9.1 0.74 8.9 9.1 1.8 1 1 0 1 1 1 0 Nucleotide-sugar transporter Halogen_Hydrol PF10112.9 KKF96946.1 - 0.22 11.5 2.0 0.9 9.5 0.1 2.7 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF202 PF02656.15 KKF96946.1 - 6.3 7.3 18.5 0.097 13.1 2.2 3.8 4 2 0 4 4 4 0 Domain of unknown function (DUF202) Bac_surface_Ag PF01103.23 KKF96947.1 - 6.7e-43 147.4 0.0 8.2e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 KKF96947.1 - 0.076 12.5 0.2 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB UQ_con PF00179.26 KKF96948.1 - 6.4e-21 74.5 0.1 8.9e-21 74.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKF96948.1 - 0.051 13.3 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B BTB PF00651.31 KKF96949.1 - 2.3e-11 43.9 0.0 5.6e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain W2 PF02020.18 KKF96949.1 - 0.029 14.5 2.8 0.029 14.5 2.8 1.8 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Methyltransf_25 PF13649.6 KKF96950.1 - 1.4e-06 28.9 0.0 3.6e-05 24.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF96950.1 - 0.00013 22.7 0.0 0.0012 19.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF96950.1 - 0.0003 21.4 0.0 0.0011 19.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF96950.1 - 0.0041 17.0 0.0 0.0085 15.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF96950.1 - 0.016 15.0 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KKF96950.1 - 0.16 11.5 0.1 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Mito_carr PF00153.27 KKF96951.1 - 8.3e-51 169.9 1.4 5.8e-16 58.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein COX7C PF02935.16 KKF96951.1 - 0.097 12.9 0.6 1.2 9.4 0.3 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc UCH_1 PF13423.6 KKF96952.1 - 4.6e-86 289.3 0.7 4.8e-52 177.5 2.5 3.8 3 1 1 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KKF96952.1 - 1.1e-44 152.9 0.0 1.5e-37 129.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KKF96952.1 - 7.7e-20 72.1 0.0 1.9e-19 70.8 0.0 1.8 1 0 0 1 1 1 1 Exonuclease ubiquitin PF00240.23 KKF96952.1 - 1.1e-09 37.9 0.0 2.3e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family FlaG PF03646.15 KKF96952.1 - 0.071 13.3 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 FlaG protein Dimerisation PF08100.11 KKF96952.1 - 0.15 12.1 0.0 0.93 9.6 0.0 2.3 2 0 0 2 2 2 0 Dimerisation domain PMT PF02366.18 KKF96953.1 - 1.8e-76 257.0 16.1 1.8e-76 257.0 16.1 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KKF96953.1 - 9.6e-63 211.4 17.3 9.6e-63 211.4 17.3 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KKF96953.1 - 2.8e-46 157.7 0.1 5.3e-46 156.8 0.1 1.4 1 0 0 1 1 1 1 MIR domain DUF2637 PF10935.8 KKF96953.1 - 3.5 7.5 12.2 0.48 10.3 7.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) Sec2p PF06428.11 KKF96954.1 - 1.2e-22 79.7 17.5 1.2e-22 79.7 17.5 2.5 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Kre28 PF17097.5 KKF96954.1 - 0.047 12.6 12.0 0.022 13.7 9.2 1.7 1 1 1 2 2 2 0 Spindle pole body component PX PF00787.24 KKF96955.1 - 1.3e-25 89.6 0.0 1.5e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 PX domain PRP21_like_P PF12230.8 KKF96956.1 - 1.7e-49 168.6 16.0 2.3e-48 164.9 16.0 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KKF96956.1 - 4.5e-37 125.8 0.5 4.7e-18 64.9 0.0 2.6 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KKF96956.1 - 0.00053 19.5 0.4 0.0009 18.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Ribosomal_60s PF00428.19 KKF96956.1 - 0.0076 16.8 1.2 0.0076 16.8 1.2 2.3 3 0 0 3 3 3 1 60s Acidic ribosomal protein FYDLN_acid PF09538.10 KKF96956.1 - 3.8 8.2 13.6 3.4 8.4 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) ARPC4 PF05856.12 KKF96957.1 - 9e-60 201.1 4.7 9.9e-60 200.9 4.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) HTH_32 PF13565.6 KKF96959.1 - 0.014 16.0 0.4 0.11 13.1 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain SUIM_assoc PF16619.5 KKF96960.1 - 0.0044 17.1 1.0 0.0044 17.1 1.0 4.9 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 KKF96960.1 - 0.028 14.8 21.1 0.78 10.1 18.0 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like DDHD PF02862.17 KKF96960.1 - 0.058 13.5 11.1 0.24 11.5 9.3 2.3 2 0 0 2 2 2 0 DDHD domain Dynamin_N PF00350.23 KKF96960.1 - 0.092 12.8 6.0 0.029 14.4 2.8 1.7 2 0 0 2 2 2 0 Dynamin family Neur_chan_memb PF02932.16 KKF96960.1 - 0.38 10.8 14.8 3.4 7.7 13.0 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.9 KKF96960.1 - 1.7 8.7 16.7 3.6 7.7 14.2 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family Tim54 PF11711.8 KKF96960.1 - 2.8 6.6 20.9 0.23 10.2 15.4 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.13 KKF96960.1 - 5.8 6.8 59.9 5.6 6.9 2.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 KKF96960.1 - 7.4 7.0 23.3 54 4.2 0.0 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF913 PF06025.12 KKF96960.1 - 7.9 5.4 12.0 15 4.4 10.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) zf-RING_2 PF13639.6 KKF96961.1 - 1.2e-12 47.9 5.8 2e-12 47.2 5.8 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 KKF96961.1 - 6.3e-11 42.1 0.0 1.7e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 KKF96961.1 - 1.3e-09 37.7 4.4 2.2e-09 37.0 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKF96961.1 - 6.4e-09 35.5 4.2 1e-08 34.9 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKF96961.1 - 1.2e-08 35.1 2.8 2.5e-08 34.1 2.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KKF96961.1 - 1.9e-07 30.9 3.0 2.9e-07 30.3 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KKF96961.1 - 2.3e-07 30.4 3.8 2.3e-07 30.4 3.8 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KKF96961.1 - 2.2e-06 27.4 2.9 3.4e-06 26.8 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKF96961.1 - 2.4e-06 27.5 2.7 2.2e-05 24.4 3.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KKF96961.1 - 0.0013 18.6 3.2 0.0022 17.8 3.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KKF96961.1 - 0.0026 17.8 2.3 0.0076 16.3 2.3 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KKF96961.1 - 0.014 15.0 2.8 0.027 14.1 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KKF96961.1 - 0.034 14.3 3.5 0.085 13.0 3.5 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KKF96961.1 - 0.13 12.1 2.8 0.23 11.3 2.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 KKF96961.1 - 0.19 11.9 5.0 0.93 9.7 4.8 2.2 2 1 1 3 3 2 0 RING-variant domain Pox_A3L PF05288.11 KKF96961.1 - 0.22 11.5 0.0 0.46 10.5 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A3L Protein FANCL_C PF11793.8 KKF96961.1 - 0.31 11.2 3.5 0.83 9.9 3.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KKF96961.1 - 0.44 10.9 3.4 0.97 9.8 3.4 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KKF96961.1 - 0.92 9.4 3.2 1.8 8.5 3.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KKF96961.1 - 1.4 8.8 3.3 2.5 8.0 3.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Filament PF00038.21 KKF96963.1 - 0.00026 20.7 6.8 0.0004 20.1 6.8 1.2 1 0 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 KKF96963.1 - 0.0018 17.2 18.4 0.048 12.5 2.9 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein GAS PF13851.6 KKF96963.1 - 0.0093 15.3 16.2 0.13 11.6 8.4 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Orthopox_F8 PF05886.11 KKF96963.1 - 0.034 14.3 1.6 3 8.0 0.0 3.0 3 0 0 3 3 3 0 Orthopoxvirus F8 protein BLOC1_2 PF10046.9 KKF96963.1 - 0.054 13.8 2.4 1.1 9.6 0.9 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cep57_CLD_2 PF14197.6 KKF96963.1 - 0.069 13.3 0.7 0.069 13.3 0.7 3.8 4 0 0 4 4 3 0 Centrosome localisation domain of PPC89 SASP PF00269.20 KKF96963.1 - 0.28 11.3 6.9 1.7 8.7 0.2 2.8 3 0 0 3 3 3 0 Small, acid-soluble spore proteins, alpha/beta type LMBR1 PF04791.16 KKF96963.1 - 0.34 9.8 1.2 0.39 9.6 1.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HrpB7 PF09486.10 KKF96963.1 - 0.46 10.9 21.6 1.5 9.2 8.6 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4201 PF13870.6 KKF96963.1 - 0.78 9.4 11.8 2.6 7.7 3.6 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) OmpH PF03938.14 KKF96963.1 - 0.92 9.8 15.8 3.7 7.9 2.7 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 KKF96963.1 - 1 8.4 18.5 2 7.4 7.5 2.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KKF96963.1 - 1.4 9.4 16.9 0.66 10.4 11.6 2.3 1 1 1 2 2 2 0 Fez1 FlaC_arch PF05377.11 KKF96963.1 - 1.4 9.4 4.0 34 4.9 0.3 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 KKF96963.1 - 1.8 8.5 11.6 2.4 8.2 3.2 2.7 3 0 0 3 3 3 0 Laminin Domain II DUF2730 PF10805.8 KKF96963.1 - 1.9 8.6 6.7 15 5.7 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) PRKG1_interact PF15898.5 KKF96963.1 - 3.2 8.7 20.3 0.43 11.5 2.0 3.0 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain AAA_13 PF13166.6 KKF96963.1 - 3.3 6.2 9.5 3 6.4 8.4 1.4 1 1 0 1 1 1 0 AAA domain BST2 PF16716.5 KKF96963.1 - 3.9 8.1 8.6 31 5.2 0.3 2.9 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 DivIC PF04977.15 KKF96963.1 - 4.2 7.2 24.2 2 8.2 2.2 3.5 2 1 1 3 3 3 0 Septum formation initiator ADIP PF11559.8 KKF96963.1 - 5.1 7.2 14.6 2.4 8.2 2.1 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YlqD PF11068.8 KKF96963.1 - 5.8 7.3 11.6 2.2 8.7 0.6 2.7 2 1 2 4 4 4 0 YlqD protein FapA PF03961.13 KKF96963.1 - 7.4 5.1 7.1 16 4.0 0.2 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A MCU PF04678.13 KKF96963.1 - 9.1 6.3 12.0 7 6.7 1.7 2.5 1 1 1 2 2 2 0 Mitochondrial calcium uniporter MFS_1 PF07690.16 KKF96964.1 - 2.2e-31 109.1 38.8 3.3e-24 85.5 18.3 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKF96964.1 - 1.9e-11 43.5 5.9 1.9e-11 43.5 5.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KKF96964.1 - 0.0019 16.7 3.4 0.0033 15.9 3.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ELP6 PF09807.9 KKF96965.1 - 6.4e-06 25.8 0.4 7.7e-05 22.2 0.1 2.0 1 1 0 2 2 2 1 Elongation complex protein 6 FANCI_S1-cap PF14674.6 KKF96965.1 - 0.3 11.2 2.4 0.82 9.8 0.2 2.3 2 0 0 2 2 2 0 FANCI solenoid 1 cap Ribosomal_L37e PF01907.19 KKF96966.1 - 4e-12 46.1 3.9 4.3e-12 46.0 3.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L37e UPF0016 PF01169.19 KKF96967.1 - 8.1e-40 135.0 25.1 9.5e-20 70.7 11.3 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 SRP-alpha_N PF04086.13 KKF96967.1 - 3.4 7.5 12.5 5.5 6.8 12.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3357 PF11837.8 KKF96967.1 - 6.6 7.2 6.5 18 5.8 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) 2OG-FeII_Oxy_2 PF13532.6 KKF96968.1 - 1.3e-30 107.1 0.0 2e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KKF96968.1 - 0.00019 21.7 0.0 0.00047 20.4 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family DUF4597 PF15366.6 KKF96968.1 - 0.0099 15.6 0.5 0.035 13.8 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4597) SHMT PF00464.19 KKF96969.1 - 4.8e-195 647.8 0.0 5.7e-195 647.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 KKF96969.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Gcn1_N PF12074.8 KKF96970.1 - 5.1e-107 358.3 9.6 1.8e-106 356.5 4.7 3.8 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 KKF96970.1 - 2.9e-59 199.3 4.1 5.5e-59 198.4 4.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT_EZ PF13513.6 KKF96970.1 - 3.7e-28 97.6 41.9 3.5e-05 24.2 0.0 20.5 16 6 8 24 24 21 6 HEAT-like repeat HEAT_2 PF13646.6 KKF96970.1 - 1.6e-27 95.7 43.1 2.5e-06 27.8 0.0 14.2 12 3 2 15 15 12 8 HEAT repeats HEAT PF02985.22 KKF96970.1 - 2.8e-24 83.1 33.4 0.14 12.5 0.0 21.2 26 0 0 26 26 23 5 HEAT repeat Cnd1 PF12717.7 KKF96970.1 - 1.7e-15 57.4 11.7 0.016 15.3 0.1 11.0 7 2 4 11 11 11 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KKF96970.1 - 1.7e-11 44.5 0.0 3.9 8.1 0.0 9.3 7 3 3 10 10 9 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KKF96970.1 - 2.7e-11 43.5 0.0 0.049 13.2 0.0 6.5 5 1 1 6 6 5 2 CLASP N terminal ParcG PF10274.9 KKF96970.1 - 7.5e-10 39.2 4.7 0.0023 18.1 0.0 7.6 9 2 1 10 10 9 2 Parkin co-regulated protein UME PF08064.13 KKF96970.1 - 3.3e-06 27.0 0.9 2.7 8.0 0.0 8.4 8 3 1 9 9 8 1 UME (NUC010) domain DUF3385 PF11865.8 KKF96970.1 - 9e-06 25.7 0.0 2.2 8.2 0.0 6.1 5 2 1 6 6 6 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 KKF96970.1 - 7.2e-05 21.5 21.4 0.15 10.6 2.1 8.3 6 3 1 8 8 8 3 Adaptin N terminal region DUF937 PF06078.11 KKF96970.1 - 0.00069 20.2 0.1 16 6.1 0.0 5.8 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF937) Tti2 PF10521.9 KKF96970.1 - 0.0018 17.9 11.0 1.5 8.3 0.0 7.4 8 1 0 8 8 8 1 Tti2 family MMS19_C PF12460.8 KKF96970.1 - 0.0034 16.6 0.3 0.0034 16.6 0.3 6.9 8 0 0 8 8 8 2 RNAPII transcription regulator C-terminal TIP120 PF08623.10 KKF96970.1 - 0.0065 16.3 7.7 0.37 10.5 0.0 6.6 6 1 1 7 7 7 1 TATA-binding protein interacting (TIP20) RasGEF_N_2 PF14663.6 KKF96970.1 - 0.015 15.7 0.1 12 6.3 0.0 4.8 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DnaB_2 PF07261.11 KKF96970.1 - 0.033 13.9 0.0 0.15 11.8 0.0 2.1 1 0 0 1 1 1 0 Replication initiation and membrane attachment TFCD_C PF12612.8 KKF96970.1 - 0.041 13.7 0.0 1.4 8.7 0.0 3.2 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal MOR2-PAG1_C PF14225.6 KKF96970.1 - 0.62 9.9 2.6 9.4 6.0 0.0 3.9 5 0 0 5 5 5 0 Cell morphogenesis C-terminal RIX1 PF08167.12 KKF96970.1 - 4 7.1 16.0 0.12 12.1 0.7 5.3 6 1 1 7 7 7 0 rRNA processing/ribosome biogenesis FAM199X PF15814.5 KKF96971.1 - 0.3 10.1 8.4 0.42 9.6 8.2 1.3 1 1 0 1 1 1 0 Protein family FAM199X RSN1_7TM PF02714.15 KKF96972.1 - 8.2e-78 261.5 19.0 8.2e-78 261.5 19.0 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKF96972.1 - 9.5e-40 135.9 4.2 9.5e-40 135.9 4.2 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKF96972.1 - 6.6e-28 98.1 0.0 1.1e-27 97.4 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KKF96972.1 - 1.6e-27 95.5 0.2 4.4e-26 90.9 0.1 2.4 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 KKF96972.1 - 0.012 15.5 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAS PF13851.6 KKF96973.1 - 0.00021 20.7 13.2 0.00021 20.7 13.2 2.0 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 KKF96973.1 - 0.044 13.2 25.3 0.077 12.4 5.8 3.1 1 1 2 3 3 3 0 Tropomyosin KASH_CCD PF14662.6 KKF96973.1 - 0.072 12.9 23.4 0.032 14.1 8.2 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Tropomyosin_1 PF12718.7 KKF96973.1 - 0.085 13.0 22.6 0.15 12.3 22.6 1.4 1 0 0 1 1 1 0 Tropomyosin like SHE3 PF17078.5 KKF96973.1 - 0.48 10.1 19.2 0.4 10.4 3.7 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.21 KKF96973.1 - 1.1 9.4 11.5 0.37 10.9 2.7 2.9 2 1 1 3 3 3 0 bZIP transcription factor TMF_DNA_bd PF12329.8 KKF96973.1 - 4.9 7.2 12.8 11 6.1 0.5 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DHR10 PF18595.1 KKF96973.1 - 6.1 6.9 28.1 11 6.1 11.4 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CHD5 PF04420.14 KKF96973.1 - 6.5 6.6 6.9 5.7 6.8 5.3 1.7 1 1 0 1 1 1 0 CHD5-like protein Laminin_II PF06009.12 KKF96973.1 - 7.3 6.6 14.5 1.6 8.7 4.4 2.6 1 1 1 2 2 2 0 Laminin Domain II Rft-1 PF04506.13 KKF96974.1 - 4.2e-66 223.7 4.2 1e-44 153.2 1.8 2.1 2 0 0 2 2 2 2 Rft protein DEAD PF00270.29 KKF96975.1 - 2.6e-51 173.9 0.0 1.5e-50 171.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF96975.1 - 9.6e-35 119.3 0.0 1.6e-31 108.9 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KKF96975.1 - 6.3e-07 29.5 1.0 1.7e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KKF96975.1 - 0.021 13.6 0.2 1.1 8.0 0.0 2.6 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF966 PF06136.13 KKF96975.1 - 1.6 8.4 13.3 2.6 7.7 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SOBP PF15279.6 KKF96975.1 - 6.3 7.3 14.2 11 6.6 14.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein RPE65 PF03055.15 KKF96976.1 - 5.9e-68 230.1 0.0 7.7e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Sugar_tr PF00083.24 KKF96977.1 - 7.5e-127 423.9 16.8 8.6e-127 423.7 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF96977.1 - 4.2e-22 78.5 17.2 4.2e-22 78.5 17.2 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily TPR_14 PF13428.6 KKF96977.1 - 0.015 16.1 0.1 0.03 15.1 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKF96977.1 - 0.057 13.9 0.0 0.096 13.2 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat UCH PF00443.29 KKF96978.1 - 7.6e-37 127.2 0.0 1.2e-36 126.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KKF96978.1 - 2.7e-17 62.3 0.0 8.1e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KKF96978.1 - 7.8e-17 61.8 0.2 7.1e-15 55.4 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KKF96978.1 - 5.8e-13 49.0 2.2 5.8e-13 49.0 2.2 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein HORMA PF02301.18 KKF96979.1 - 6.2e-34 117.4 0.0 9.7e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KKF96979.1 - 0.007 16.4 0.1 0.034 14.1 0.1 2.1 1 1 0 1 1 1 1 Autophagy-related protein 101 PH_10 PF15411.6 KKF96979.1 - 0.17 12.2 1.4 0.35 11.1 0.4 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Mitochondr_Som1 PF11093.8 KKF96980.1 - 3.1e-19 68.8 0.4 4e-19 68.4 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 IMPa_N_2 PF18650.1 KKF96980.1 - 0.12 11.6 0.4 0.55 9.5 0.0 1.8 1 1 1 2 2 2 0 Immunomodulating metalloprotease N-terminal domain Ribosomal_L22 PF00237.19 KKF96981.1 - 1.1e-18 67.3 0.1 2.6e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF480 PF04337.12 KKF96981.1 - 0.069 13.2 0.1 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF480 DUF4065 PF13274.6 KKF96981.1 - 0.11 13.4 0.0 0.4 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) DUF4064 PF13273.6 KKF96982.1 - 0.0022 18.2 0.3 0.0034 17.6 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4064) SKG6 PF08693.10 KKF96982.1 - 0.0062 15.9 0.7 0.012 15.0 0.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MLANA PF14991.6 KKF96982.1 - 0.0083 16.4 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein melan-A Mid2 PF04478.12 KKF96982.1 - 0.065 13.1 0.3 0.13 12.1 0.2 1.5 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor RRM_1 PF00076.22 KKF96983.1 - 2.5e-46 155.4 0.1 2.2e-15 56.2 0.1 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKF96983.1 - 1.7e-38 130.3 0.0 9.1e-28 95.9 0.0 4.4 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_5 PF13893.6 KKF96983.1 - 2e-07 30.7 0.0 0.00041 19.9 0.0 3.7 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KKF96983.1 - 0.0042 17.1 2.3 1.4 9.0 0.0 3.9 5 0 0 5 5 5 1 RNA binding motif RRM_7 PF16367.5 KKF96983.1 - 0.0094 16.1 0.0 3.3 7.9 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KKF96983.1 - 0.041 13.9 0.0 7.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Spt20 PF12090.8 KKF96983.1 - 0.18 11.4 5.8 0.38 10.3 5.8 1.5 1 0 0 1 1 1 0 Spt20 family Helicase_C PF00271.31 KKF96984.1 - 5.6e-15 55.7 0.0 2.1e-14 53.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KKF96984.1 - 2e-14 53.7 3.5 2.5e-14 53.5 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 KKF96984.1 - 1.1e-12 48.1 0.0 2.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKF96984.1 - 1.6e-06 28.4 0.5 5.6e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 KKF96984.1 - 0.0018 18.6 0.0 0.0046 17.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Rad17 PF03215.15 KKF96984.1 - 0.018 15.0 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KKF96984.1 - 0.024 15.1 0.4 0.14 12.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 KKF96984.1 - 0.033 14.7 0.0 0.033 14.7 0.0 3.3 4 0 0 4 4 4 0 AAA domain RuvA_C PF07499.13 KKF96984.1 - 0.068 13.6 0.0 0.068 13.6 0.0 3.7 4 1 1 5 5 4 0 RuvA, C-terminal domain FtsK_SpoIIIE PF01580.18 KKF96984.1 - 0.074 12.4 0.0 0.21 10.9 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase PF06745.13 KKF96984.1 - 0.074 12.4 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 KKF96984.1 - 0.13 12.3 0.1 4.4 7.3 0.1 2.7 1 1 0 1 1 1 0 AAA domain PI-PLC-X PF00388.19 KKF96985.1 - 2e-10 40.4 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain His_biosynth PF00977.21 KKF96985.1 - 0.022 14.2 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein THF_DHG_CYH PF00763.23 KKF96986.1 - 4.4e-25 88.2 0.0 6.9e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KKF96986.1 - 4.6e-14 52.0 0.0 5.7e-08 32.2 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MMS19_N PF14500.6 KKF96987.1 - 1.5e-42 146.0 1.4 2.6e-42 145.2 0.1 2.1 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II NUFIP1 PF10453.9 KKF96988.1 - 2.7e-09 36.7 1.9 2.7e-09 36.7 1.9 2.3 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 KKF96988.1 - 0.0031 17.5 6.6 0.0046 17.0 6.6 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KKF96988.1 - 0.16 11.9 5.0 0.23 11.4 5.0 1.2 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KKF96988.1 - 0.22 12.0 4.5 0.42 11.2 4.5 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Bac_small_YrzI PF09501.10 KKF96988.1 - 1.2 9.4 0.0 1.2 9.4 0.0 2.5 2 1 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) zf-CCCH_4 PF18044.1 KKF96988.1 - 5.8 6.8 6.4 16 5.5 6.4 1.7 1 1 0 1 1 1 0 CCCH-type zinc finger Folliculin PF11704.8 KKF96988.1 - 6.3 6.6 8.6 4.9 7.0 0.3 2.5 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Torus PF16131.5 KKF96988.1 - 8.1 7.2 8.5 32 5.3 8.5 2.0 1 1 0 1 1 1 0 Torus domain RNA_pol_Rbc25 PF08292.12 KKF96989.1 - 4.8e-31 107.7 1.2 3.4e-30 104.9 1.2 2.0 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KKF96989.1 - 4.5e-15 55.8 0.0 6.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 EMC3_TMCO1 PF01956.16 KKF96990.1 - 1.2e-50 171.5 1.4 1.6e-50 171.2 1.4 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 KKF96991.1 - 1.7e-49 167.8 0.1 2e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) SPT2 PF08243.11 KKF96992.1 - 3.7e-15 56.4 24.3 3.7e-15 56.4 24.3 2.4 2 0 0 2 2 2 1 SPT2 chromatin protein Pex14_N PF04695.13 KKF96992.1 - 0.2 12.3 6.4 0.37 11.4 6.4 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Myc_N PF01056.18 KKF96992.1 - 0.4 10.5 11.1 0.19 11.6 9.1 1.3 1 1 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.19 KKF96993.1 - 2.6e-26 92.0 11.6 3e-26 91.8 11.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KKF96993.1 - 0.00082 19.7 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain RibD_C PF01872.17 KKF96993.1 - 0.055 13.3 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 RibD C-terminal domain UBA_6 PF18039.1 KKF96993.1 - 0.085 12.8 1.6 0.097 12.6 0.2 1.7 2 0 0 2 2 2 0 UBA-like domain TFIID_30kDa PF03540.13 KKF96993.1 - 0.099 12.6 0.0 0.3 11.1 0.0 1.8 1 1 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Npun_R1517 PF18068.1 KKF96993.1 - 0.1 12.9 0.2 0.14 12.5 0.2 1.2 1 0 0 1 1 1 0 Npun R1517 Pkinase PF00069.25 KKF96994.1 - 2.7e-46 158.1 0.0 4e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF96994.1 - 6.7e-19 68.2 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKF96994.1 - 0.00017 21.6 0.8 0.61 10.0 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 KKF96994.1 - 0.014 15.0 0.1 0.045 13.3 0.1 1.8 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KKF96994.1 - 0.06 12.6 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Ribosomal_L21p PF00829.21 KKF96995.1 - 2.2e-08 34.3 0.0 2.7e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein CRC_subunit PF08624.10 KKF96996.1 - 7.2e-52 175.4 0.0 1.4e-51 174.5 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Ribosomal_S8e PF01201.22 KKF96996.1 - 9.2e-28 97.1 2.6 2.1e-27 95.9 2.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S8e Cyclin PF08613.11 KKF96997.1 - 2.2e-10 41.1 0.0 3.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KKF96997.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Tim54 PF11711.8 KKF96998.1 - 1.3e-124 415.8 0.7 3.7e-87 292.5 0.5 2.0 1 1 1 2 2 2 2 Inner membrane protein import complex subunit Tim54 Nefa_Nip30_N PF10187.9 KKF96999.1 - 1.4e-28 99.3 11.4 2.4e-28 98.5 11.4 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Dehydratase_SU PF02287.15 KKF96999.1 - 0.035 14.2 1.7 0.048 13.7 1.7 1.3 1 0 0 1 1 1 0 Dehydratase small subunit MOZART2 PF12926.7 KKF96999.1 - 0.097 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated APG6_N PF17675.1 KKF96999.1 - 0.96 10.0 11.4 1.3 9.5 11.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 KKF96999.1 - 1.7 7.9 7.4 2.3 7.5 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 KKF97000.1 - 4.3e-58 196.7 0.0 6.2e-57 192.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF97000.1 - 1.5e-27 96.5 0.1 2.6e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KKF97000.1 - 0.0001 21.4 0.2 0.0002 20.4 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KKF97000.1 - 0.00061 19.8 0.5 0.085 12.8 0.4 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKF97000.1 - 0.00081 18.8 0.5 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKF97000.1 - 0.0095 15.3 0.8 0.018 14.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KKF97000.1 - 0.011 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KKF97000.1 - 0.1 11.5 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KKF97000.1 - 1.2 8.7 3.7 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 RIO1 family SF3A2 PF16835.5 KKF97001.1 - 1.1e-33 115.4 0.1 1.6e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KKF97001.1 - 3.9e-06 27.1 0.9 6.8e-06 26.3 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KKF97001.1 - 9.2e-05 22.4 0.1 0.00014 21.7 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KKF97001.1 - 0.058 13.0 1.5 0.11 12.1 1.5 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like AAA PF00004.29 KKF97002.1 - 2.1e-42 144.7 0.0 3.9e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKF97002.1 - 6.1e-12 45.3 0.1 6.4e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KKF97002.1 - 6.4e-10 38.7 0.2 1.3e-09 37.7 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKF97002.1 - 1.7e-07 31.8 0.0 6.7e-05 23.3 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KKF97002.1 - 1.3e-06 28.4 0.1 3.2e-05 23.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KKF97002.1 - 3.4e-06 27.3 0.0 9.3e-06 25.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKF97002.1 - 6.8e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KKF97002.1 - 0.00018 21.8 0.1 0.0036 17.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KKF97002.1 - 0.00024 20.3 0.0 0.00076 18.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KKF97002.1 - 0.00073 20.1 0.0 0.0023 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KKF97002.1 - 0.0011 18.5 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KKF97002.1 - 0.0019 17.5 0.0 0.0043 16.3 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KKF97002.1 - 0.0032 17.6 0.0 0.0086 16.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KKF97002.1 - 0.0037 16.7 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KKF97002.1 - 0.0042 17.1 0.0 0.0097 15.9 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KKF97002.1 - 0.0047 16.7 0.1 0.013 15.3 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KKF97002.1 - 0.006 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Prot_ATP_OB_N PF17758.1 KKF97002.1 - 0.0062 16.2 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain AAA_14 PF13173.6 KKF97002.1 - 0.0073 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KKF97002.1 - 0.0082 15.9 0.0 0.028 14.1 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KKF97002.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KKF97002.1 - 0.025 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KKF97002.1 - 0.026 13.9 0.7 0.13 11.5 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 KKF97002.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKF97002.1 - 0.052 13.5 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 KKF97002.1 - 0.053 13.3 0.4 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKF97002.1 - 0.053 13.1 0.1 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KKF97002.1 - 0.06 13.6 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 KKF97002.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Thymidylate_kin PF02223.17 KKF97002.1 - 0.091 12.4 0.0 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase eIF-1a PF01176.19 KKF97002.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 1 0 Translation initiation factor 1A / IF-1 Zeta_toxin PF06414.12 KKF97002.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 KKF97002.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4200 PF13863.6 KKF97002.1 - 1.1 9.6 5.6 0.29 11.5 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) SIS PF01380.22 KKF97003.1 - 2e-61 205.6 0.1 1.1e-31 109.4 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KKF97003.1 - 3.6e-18 66.0 0.0 6.9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KKF97003.1 - 3.3e-10 39.9 0.0 8.1e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KKF97003.1 - 0.00072 18.5 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KKF97003.1 - 0.076 13.0 0.0 1.4 8.9 0.0 2.6 2 1 0 2 2 2 0 SIS domain Proteasome PF00227.26 KKF97004.1 - 6.3e-30 104.1 0.0 7.6e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HMG_box_2 PF09011.10 KKF97005.1 - 4.5e-12 46.4 5.4 2.9e-06 27.8 0.6 2.9 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 KKF97005.1 - 1.2e-11 44.8 0.2 1.2e-11 44.8 0.2 3.3 2 1 1 3 3 3 2 HMG (high mobility group) box Dicty_REP PF05086.12 KKF97005.1 - 2 6.3 5.0 2.1 6.2 5.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NACHT_N PF17100.5 KKF97007.1 - 3.9e-65 219.8 0.6 7.8e-65 218.8 0.6 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 KKF97007.1 - 3.9e-64 211.1 18.2 7.9e-12 45.5 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF97007.1 - 8.8e-28 96.4 5.4 3.4e-05 24.1 0.1 5.9 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KKF97007.1 - 1.1e-17 64.5 0.0 3.3e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Ge1_WD40 PF16529.5 KKF97007.1 - 6e-09 35.3 8.6 0.0001 21.4 0.9 4.0 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Robl_LC7 PF03259.17 KKF97007.1 - 1.8e-05 24.4 0.8 4.6 7.1 0.0 5.1 2 2 3 5 5 5 1 Roadblock/LC7 domain PD40 PF07676.12 KKF97007.1 - 0.00022 21.1 0.0 37 4.4 0.0 5.5 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KKF97007.1 - 0.00027 19.8 11.2 0.12 11.0 0.7 4.9 1 1 4 5 5 5 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KKF97007.1 - 0.0075 15.6 0.2 4.5 6.5 0.1 3.7 1 1 2 4 4 4 1 WD40-like domain FlgD_ig PF13860.6 KKF97007.1 - 0.0084 16.0 5.5 0.87 9.5 0.3 3.1 1 1 1 3 3 3 2 FlgD Ig-like domain Cytochrom_D1 PF02239.16 KKF97007.1 - 0.025 13.1 0.4 0.32 9.5 0.1 2.3 1 1 0 2 2 2 0 Cytochrome D1 heme domain AAA_11 PF13086.6 KKF97007.1 - 0.033 14.0 0.7 0.53 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KKF97007.1 - 0.034 14.0 0.0 0.13 12.1 0.0 2.0 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF5114 PF17141.4 KKF97007.1 - 0.041 14.4 1.7 13 6.4 0.0 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF5114) Big_7 PF17957.1 KKF97007.1 - 0.09 13.6 20.7 13 6.7 0.5 5.5 1 1 4 5 5 5 0 Bacterial Ig domain Borrelia_P83 PF05262.11 KKF97007.1 - 0.16 10.4 5.0 0.25 9.8 5.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein BHD_3 PF10405.9 KKF97008.1 - 5.1e-24 84.5 0.1 1e-23 83.5 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KKF97008.1 - 1.1e-19 69.9 0.1 2e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KKF97008.1 - 2.6e-12 47.5 0.2 2.6e-12 47.5 0.2 2.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 SNF2_N PF00176.23 KKF97009.1 - 4.9e-68 229.4 3.7 3.3e-64 216.8 0.8 3.4 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KKF97009.1 - 2.5e-16 60.0 0.0 7.4e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF97009.1 - 5e-06 26.6 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKF97009.1 - 2.6e-05 24.1 0.0 6.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase VHS PF00790.19 KKF97010.1 - 9.4e-33 113.0 0.9 1.6e-32 112.3 0.1 1.8 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 KKF97010.1 - 1.3e-13 50.3 0.1 2.3e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKF97010.1 - 5.6e-13 48.5 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKF97010.1 - 1.9e-12 46.7 0.0 3.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KKF97010.1 - 3.6e-11 43.2 0.4 9.6e-11 41.8 0.4 1.8 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KKF97010.1 - 0.0053 16.6 4.7 0.013 15.4 4.7 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif Hrs_helical PF12210.8 KKF97010.1 - 0.011 16.2 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate GTP_EFTU PF00009.27 KKF97011.1 - 1.6e-42 145.2 0.0 2.8e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KKF97011.1 - 1.9e-28 99.0 0.1 7.1e-28 97.1 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKF97011.1 - 8.7e-10 38.9 0.2 8.7e-10 38.9 0.2 2.6 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKF97011.1 - 0.0017 18.4 0.0 0.01 15.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Mitofilin PF09731.9 KKF97011.1 - 1.4 7.6 18.3 2.5 6.9 18.3 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HSP90 PF00183.18 KKF97011.1 - 3 6.6 9.1 5.7 5.7 9.1 1.4 1 0 0 1 1 1 0 Hsp90 protein CDC27 PF09507.10 KKF97011.1 - 7.7 5.8 25.0 13 5.1 25.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CPSF100_C PF13299.6 KKF97011.1 - 9.2 6.4 12.1 40 4.3 7.3 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PEPCK_ATP PF01293.20 KKF97012.1 - 1.1e-214 713.4 0.0 1.3e-214 713.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.6 KKF97012.1 - 0.15 11.6 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKF97012.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 KKF97013.1 - 0.027 14.2 1.3 0.045 13.5 1.3 1.3 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 KKF97014.1 - 2.8e-49 167.1 0.1 2.5e-26 92.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KKF97014.1 - 2.7e-27 95.8 55.2 2.5e-15 56.4 29.1 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KKF97014.1 - 4.2e-24 85.9 0.5 8.3e-06 25.8 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKF97014.1 - 3.3e-09 36.3 2.6 0.00031 20.4 0.3 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 KKF97014.1 - 9e-09 35.1 3.6 0.094 12.1 0.2 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKF97014.1 - 5e-07 30.4 1.8 0.011 16.3 0.2 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKF97014.1 - 6.7e-06 26.1 0.2 0.064 13.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KKF97014.1 - 1.1e-05 25.3 0.0 0.071 12.8 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_27 PF13514.6 KKF97014.1 - 7.4e-05 22.4 0.3 0.12 12.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKF97014.1 - 0.00019 21.8 0.1 0.18 12.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KKF97014.1 - 0.00036 19.9 0.6 0.12 11.7 0.2 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 KKF97014.1 - 0.0022 17.7 1.6 1 9.1 0.2 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KKF97014.1 - 0.004 17.4 0.2 1.6 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KKF97014.1 - 0.0055 16.6 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain MeaB PF03308.16 KKF97014.1 - 0.01 14.8 0.7 0.5 9.3 0.2 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 KKF97014.1 - 0.011 14.9 0.0 0.082 12.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit DUF4162 PF13732.6 KKF97014.1 - 0.022 15.5 0.0 2.8 8.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) AAA_18 PF13238.6 KKF97014.1 - 0.028 15.0 0.1 4.3 7.9 0.1 2.9 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 KKF97014.1 - 0.032 13.9 0.5 6.4 6.4 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ploopntkinase1 PF18748.1 KKF97014.1 - 0.037 13.5 0.0 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 MukB PF04310.12 KKF97014.1 - 0.043 13.6 0.1 9.3 6.0 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_28 PF13521.6 KKF97014.1 - 0.05 13.8 1.2 1.6 9.0 0.4 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKF97014.1 - 0.079 12.5 1.1 22 4.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KKF97014.1 - 0.12 11.7 0.4 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KKF97014.1 - 0.13 12.6 0.0 8.3 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KKF97014.1 - 0.23 11.2 0.7 17 5.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain p450 PF00067.22 KKF97015.1 - 1.9e-39 135.7 0.0 2.3e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CK_II_beta PF01214.18 KKF97016.1 - 3.8e-74 248.4 0.0 8.8e-74 247.3 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit CDC45 PF02724.14 KKF97016.1 - 1.5 7.0 6.0 2.1 6.5 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Cupin_8 PF13621.6 KKF97017.1 - 1.3e-22 80.7 0.0 1.9e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain ApbA_C PF08546.11 KKF97018.1 - 2e-26 92.7 0.0 3.1e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KKF97018.1 - 7.1e-20 71.2 0.0 9.6e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Zn_clus PF00172.18 KKF97020.1 - 2.5e-08 33.9 9.4 4.6e-08 33.1 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKF97020.1 - 6.9e-08 31.9 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain LpxD PF04613.14 KKF97020.1 - 0.029 14.1 0.0 0.084 12.7 0.0 1.7 1 1 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD TRAUB PF08164.12 KKF97021.1 - 3.6e-28 97.9 0.5 3.6e-28 97.9 0.5 2.7 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KKF97021.1 - 3.2e-26 92.7 1.8 3.2e-26 92.7 1.8 4.1 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor BUD22 PF09073.10 KKF97023.1 - 9.7e-82 275.6 48.9 1e-80 272.3 48.9 1.9 1 1 0 1 1 1 1 BUD22 Chal_sti_synt_C PF02797.15 KKF97023.1 - 1.2e-22 80.6 0.0 2.4e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 KKF97023.1 - 3e-18 66.1 0.1 5.7e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.10 KKF97023.1 - 2.3e-05 24.5 0.0 7e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.12 KKF97023.1 - 0.00094 18.6 0.0 0.0023 17.3 0.0 1.6 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein K_channel_TID PF07941.11 KKF97023.1 - 1.4 9.4 4.1 14 6.2 0.3 2.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Mito_carr PF00153.27 KKF97024.1 - 1.8e-52 175.3 0.7 1.3e-19 69.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NACHT_N PF17100.5 KKF97025.1 - 7.5e-48 163.3 0.3 7.5e-48 163.3 0.3 2.1 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KKF97025.1 - 2.5e-06 27.5 0.6 1.4e-05 25.1 0.1 2.4 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.6 KKF97025.1 - 0.00074 19.4 1.7 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKF97025.1 - 0.0067 16.8 0.1 0.14 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KKF97025.1 - 0.016 14.4 0.3 0.041 13.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.15 KKF97025.1 - 0.017 15.1 0.9 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ParE_toxin PF05016.15 KKF97025.1 - 0.019 15.6 0.2 1.7 9.3 0.1 3.2 4 0 0 4 4 4 0 ParE toxin of type II toxin-antitoxin system, parDE YfdX PF10938.8 KKF97025.1 - 0.021 14.7 3.4 0.55 10.2 1.4 2.4 2 0 0 2 2 2 0 YfdX protein DASH_Dam1 PF08653.10 KKF97025.1 - 0.045 13.6 1.0 0.97 9.3 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 RNA_helicase PF00910.22 KKF97025.1 - 0.046 14.1 0.4 0.52 10.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Endotoxin_N PF03945.14 KKF97025.1 - 0.055 13.2 1.5 0.12 12.0 1.3 1.7 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain AAA_22 PF13401.6 KKF97025.1 - 0.11 12.8 0.0 0.5 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKF97025.1 - 0.13 12.6 0.2 1.1 9.7 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain DUF4050 PF13259.6 KKF97025.1 - 0.2 12.0 2.9 6.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) CP12 PF02672.15 KKF97025.1 - 0.23 12.2 3.2 0.87 10.4 3.2 2.1 1 0 0 1 1 1 0 CP12 domain DUF445 PF04286.12 KKF97025.1 - 9.4 5.9 10.4 22 4.7 10.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Ureidogly_lyase PF04115.12 KKF97026.1 - 1.5e-59 200.9 0.0 2.1e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase MFS_1 PF07690.16 KKF97027.1 - 1.1e-32 113.3 29.6 1.1e-32 113.3 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Formyl_trans_N PF00551.19 KKF97027.1 - 1.9e-19 70.1 0.0 2.7e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Sugar_tr PF00083.24 KKF97027.1 - 9.7e-08 31.3 10.6 9.7e-08 31.3 10.6 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KKF97027.1 - 0.025 12.9 4.7 0.025 12.9 2.1 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family HRI1 PF16815.5 KKF97028.1 - 2e-41 142.2 0.0 2.3e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 Chitin_synth_1 PF01644.17 KKF97030.1 - 1.8e-73 245.9 0.1 3e-73 245.2 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KKF97030.1 - 5.1e-29 100.0 0.0 1.1e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KKF97030.1 - 2.2e-20 72.8 3.2 9.5e-16 57.5 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KKF97030.1 - 8.9e-05 22.5 11.4 8.9e-05 22.5 11.4 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 GHMP_kinases_N PF00288.26 KKF97031.1 - 6.2e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKF97031.1 - 0.00011 22.5 0.0 0.00029 21.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DUF676 PF05057.14 KKF97032.1 - 3.1e-48 164.2 0.0 4.3e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KKF97032.1 - 0.00023 21.1 0.0 0.00039 20.3 0.0 1.4 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KKF97032.1 - 0.011 16.3 0.3 0.039 14.5 0.1 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KKF97032.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 KKF97032.1 - 0.12 12.0 0.2 0.52 9.9 0.0 2.1 4 0 0 4 4 4 0 alpha/beta hydrolase fold LCAT PF02450.15 KKF97032.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1943 PF09172.11 KKF97033.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Band_7 PF01145.25 KKF97034.1 - 1.7e-24 86.8 7.2 4e-24 85.6 7.2 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KKF97034.1 - 0.00069 18.8 4.3 0.001 18.2 4.3 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 KKF97034.1 - 0.033 13.9 0.1 0.06 13.0 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family UcrQ PF02939.16 KKF97035.1 - 1.9e-37 127.0 2.2 2.3e-37 126.8 2.2 1.1 1 0 0 1 1 1 1 UcrQ family Ribosomal_L7Ae PF01248.26 KKF97036.1 - 5e-20 71.0 0.5 5e-20 71.0 0.5 2.5 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_S20p PF01649.18 KKF97036.1 - 0.0095 16.6 0.3 0.0095 16.6 0.3 3.2 3 0 0 3 3 3 1 Ribosomal protein S20 SAPS PF04499.15 KKF97036.1 - 0.19 10.5 1.5 0.28 9.9 1.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SART-1 PF03343.13 KKF97036.1 - 0.57 8.7 23.3 1.4 7.4 23.3 1.7 1 1 0 1 1 1 0 SART-1 family DUF1761 PF08570.10 KKF97037.1 - 4e-25 88.5 0.9 4.7e-25 88.3 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) NIF PF03031.18 KKF97038.1 - 2e-56 190.1 0.0 2.7e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4808 PF16066.5 KKF97038.1 - 0.015 15.9 0.2 0.12 13.0 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) IF-2B PF01008.17 KKF97039.1 - 2.9e-39 135.0 2.5 4.6e-36 124.5 2.5 2.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF4154 PF13689.6 KKF97039.1 - 0.074 13.3 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 YfiR/HmsC-like Acetyltransf_1 PF00583.25 KKF97040.1 - 1e-13 51.5 0.0 1.8e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKF97040.1 - 2.7e-08 33.8 0.2 4.8e-08 33.0 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKF97040.1 - 1.7e-07 31.1 0.1 2.7e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KKF97040.1 - 1.5e-06 28.5 0.0 2.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKF97040.1 - 0.0021 18.1 0.1 0.0041 17.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KKF97040.1 - 0.011 15.2 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 KKF97040.1 - 0.18 11.8 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase adh_short PF00106.25 KKF97041.1 - 5e-45 153.4 0.6 6.2e-45 153.1 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF97041.1 - 2.4e-44 151.7 3.3 1.9e-39 135.6 1.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF97041.1 - 8.9e-17 61.6 1.1 1.2e-16 61.1 1.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKF97041.1 - 6.8e-07 29.0 0.6 7.2e-06 25.6 0.6 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKF97041.1 - 0.0097 15.3 0.1 1.1 8.6 0.0 2.5 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase IlvN PF07991.12 KKF97041.1 - 0.029 13.9 0.9 0.057 13.0 0.9 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain YAcAr PF10686.9 KKF97041.1 - 1.2 9.2 5.6 22 5.1 0.4 3.2 2 1 1 3 3 3 0 YspA, cpYpsA-related SLOG family Yae1_N PF09811.9 KKF97042.1 - 3.4e-09 36.3 2.8 4.9e-09 35.7 2.8 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal CI-B14_5a PF07347.12 KKF97043.1 - 0.043 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) AhpC-TSA PF00578.21 KKF97044.1 - 2.3e-22 79.2 0.0 4e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKF97044.1 - 8.9e-15 54.7 0.0 1.6e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KKF97044.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme FA_desaturase PF00487.24 KKF97045.1 - 8.8e-27 94.5 14.9 8.8e-27 94.5 14.9 1.8 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 KKF97045.1 - 1.7e-18 65.8 0.2 3.3e-18 64.9 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) NmrA PF05368.13 KKF97046.1 - 1.1e-28 100.4 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKF97046.1 - 5.4e-11 42.7 0.1 9.7e-11 41.9 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KKF97046.1 - 2.9e-05 24.2 0.2 5.1e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KKF97046.1 - 0.0014 19.0 0.1 0.0026 18.2 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KKF97046.1 - 0.0048 15.9 0.0 0.0085 15.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KKF97046.1 - 0.012 15.8 0.5 0.029 14.6 0.2 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KKF97046.1 - 0.042 13.3 0.0 0.095 12.1 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.16 KKF97046.1 - 0.11 13.2 0.5 0.59 10.9 0.1 2.2 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Motile_Sperm PF00635.26 KKF97047.1 - 1.4e-27 95.6 0.3 2.9e-27 94.7 0.2 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KKF97047.1 - 0.058 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin UBX PF00789.20 KKF97048.1 - 5.9e-07 29.6 0.0 5.9e-07 29.6 0.0 2.2 3 0 0 3 3 3 1 UBX domain UBA PF00627.31 KKF97048.1 - 0.061 13.3 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 UBA/TS-N domain AAA_15 PF13175.6 KKF97048.1 - 2.7 7.6 14.9 3.4 7.3 14.9 1.1 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_60s PF00428.19 KKF97049.1 - 2.4e-27 95.4 10.5 2.9e-27 95.1 10.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein KfrA_N PF11740.8 KKF97049.1 - 0.034 14.8 5.4 0.061 14.0 5.4 1.3 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Phage_holin_6_1 PF09682.10 KKF97049.1 - 0.39 11.2 1.7 2.6 8.5 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF2408 PF10303.9 KKF97050.1 - 2.4e-39 135.0 1.9 2.3e-23 83.2 0.0 4.9 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) DUF1682 PF07946.14 KKF97050.1 - 0.00023 20.5 2.3 0.00043 19.6 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) YCII PF03795.14 KKF97051.1 - 3e-10 40.3 0.0 3.6e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain AMP-binding PF00501.28 KKF97052.1 - 1.2e-85 287.7 0.0 1.4e-85 287.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKF97052.1 - 2.5e-15 57.2 0.2 1.4e-14 54.8 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KKF97052.1 - 3e-05 23.1 0.1 0.00026 20.0 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 KKF97052.1 - 0.0058 16.7 0.3 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 RTX C-terminal domain G-patch PF01585.23 KKF97053.1 - 1.2e-10 41.1 0.6 1.2e-10 41.1 0.6 1.9 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 KKF97053.1 - 5e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cu_amine_oxid PF01179.20 KKF97054.1 - 3.7e-160 533.3 0.0 4.3e-160 533.1 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KKF97054.1 - 0.016 15.6 0.1 0.068 13.6 0.0 2.0 2 0 0 2 2 2 0 Copper amine oxidase, N3 domain Recep_L_domain PF01030.24 KKF97055.1 - 2e-08 34.3 8.6 0.047 13.8 0.1 4.2 2 2 2 4 4 4 4 Receptor L domain LRR_5 PF13306.6 KKF97055.1 - 1.5e-05 24.9 2.9 0.00089 19.2 0.2 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Bactofilin PF04519.13 KKF97055.1 - 0.14 12.4 2.8 10 6.5 0.2 3.2 2 1 0 2 2 2 0 Polymer-forming cytoskeletal Spindle_Spc25 PF08234.12 KKF97056.1 - 1.9e-15 56.8 0.0 4.3e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 HhH-GPD PF00730.25 KKF97056.1 - 2e-08 34.6 0.0 4.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_S17e PF00833.18 KKF97056.1 - 0.0097 15.8 2.2 0.018 15.0 2.2 1.4 1 0 0 1 1 1 1 Ribosomal S17 GAS PF13851.6 KKF97056.1 - 0.16 11.3 11.4 0.29 10.5 11.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KKF97056.1 - 0.34 10.0 9.1 0.52 9.3 9.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KKF97056.1 - 4 7.5 10.4 6.4 6.8 10.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 KKF97056.1 - 6.3 6.1 7.9 11 5.3 7.9 1.3 1 0 0 1 1 1 0 FAM76 protein Bap31_Bap29_C PF18035.1 KKF97056.1 - 7.7 6.6 10.1 44 4.2 7.9 3.3 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Rrn6 PF10214.9 KKF97057.1 - 9.3e-69 232.9 18.0 5e-31 108.0 0.1 3.5 2 1 1 3 3 3 3 RNA polymerase I-specific transcription-initiation factor PITH PF06201.13 KKF97057.1 - 1.4e-41 142.2 0.0 3.1e-41 141.1 0.0 1.6 1 0 0 1 1 1 1 PITH domain Ribosomal_L3 PF00297.22 KKF97057.1 - 1.8e-12 46.9 6.7 3.8e-12 45.9 2.6 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 KKF97058.1 - 2.3e-40 137.0 0.0 3.2e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2384 PF09722.10 KKF97059.1 - 0.0056 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) Ank_2 PF12796.7 KKF97060.1 - 2e-29 102.0 0.3 1.5e-09 38.3 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKF97060.1 - 8.8e-26 89.9 4.9 3.7e-10 40.1 0.0 5.5 4 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKF97060.1 - 3.5e-21 75.0 5.5 0.0002 21.6 0.0 6.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKF97060.1 - 6.9e-20 69.0 6.9 6.7e-05 23.0 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KKF97060.1 - 1.7e-14 53.5 6.7 0.00014 22.2 0.0 7.1 6 1 1 7 7 7 3 Ankyrin repeat SPX PF03105.19 KKF97060.1 - 1.3e-10 41.8 11.0 6.2e-09 36.2 1.4 2.4 1 1 1 2 2 2 2 SPX domain GDPD PF03009.17 KKF97060.1 - 6.7e-06 26.0 0.0 5e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family RVP PF00077.20 KKF97060.1 - 0.031 14.6 0.0 0.084 13.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease OmpH PF03938.14 KKF97060.1 - 1.4 9.2 3.8 3.3 8.1 3.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CUE PF02845.16 KKF97061.1 - 3.1e-10 39.5 0.0 6.3e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain PPR_2 PF13041.6 KKF97062.1 - 3.5e-44 148.8 12.4 4.8e-09 36.3 0.0 14.4 12 3 4 16 16 16 8 PPR repeat family PPR_3 PF13812.6 KKF97062.1 - 7.2e-33 112.5 0.1 0.0018 18.3 0.0 10.4 9 2 1 10 10 10 8 Pentatricopeptide repeat domain PPR PF01535.20 KKF97062.1 - 4.5e-28 95.5 24.0 0.00043 20.4 0.0 14.9 17 0 0 17 17 17 6 PPR repeat PPR_1 PF12854.7 KKF97062.1 - 7.1e-21 73.6 8.9 1.4e-07 31.1 0.0 9.9 12 0 0 12 12 12 4 PPR repeat PPR_long PF17177.4 KKF97062.1 - 2.7e-17 62.9 7.6 1.8e-07 30.8 0.0 6.4 4 1 1 6 6 6 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KKF97062.1 - 4e-05 24.0 0.0 0.0021 18.4 0.0 3.2 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 KKF97062.1 - 0.003 18.3 4.4 88 4.3 0.2 7.8 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKF97062.1 - 0.034 14.0 1.3 21 5.1 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKF97062.1 - 0.099 12.9 4.4 23 5.4 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat UMP1 PF05348.11 KKF97063.1 - 2e-40 137.7 0.0 2.4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.6 KKF97064.1 - 3.5e-10 40.0 0.0 6.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KKF97064.1 - 0.0012 19.4 0.0 0.0027 18.2 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KKF97064.1 - 0.0062 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Adaptin_N PF01602.20 KKF97065.1 - 1.1e-120 403.7 11.6 1.4e-120 403.3 11.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KKF97065.1 - 2.7e-55 186.8 0.5 2.7e-55 186.8 0.5 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKF97065.1 - 1.9e-14 53.8 5.4 2.1e-06 28.1 0.2 5.1 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 KKF97065.1 - 5.2e-11 41.8 3.2 0.00011 22.2 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KKF97065.1 - 1.3e-06 28.8 2.6 0.58 10.7 0.0 5.8 4 1 1 5 5 5 2 HEAT-like repeat CLASP_N PF12348.8 KKF97065.1 - 0.0012 18.5 2.3 0.08 12.5 0.0 3.1 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.23 KKF97065.1 - 0.11 12.6 2.3 1.2e+02 2.9 0.1 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF1077 PF06417.12 KKF97066.1 - 1.2e-40 138.2 2.3 1.9e-40 137.6 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Syntaxin-18_N PF10496.9 KKF97066.1 - 1.7e-07 31.4 0.1 4.2e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus ST7 PF04184.12 KKF97066.1 - 0.097 11.1 0.8 0.12 10.8 0.1 1.4 2 0 0 2 2 2 0 ST7 protein SPOUT_MTase_2 PF14419.6 KKF97066.1 - 0.12 11.8 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Chitin_synth_1 PF01644.17 KKF97067.1 - 1.9e-78 262.1 0.3 2.9e-78 261.5 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KKF97067.1 - 1.5e-27 95.4 0.2 3.3e-27 94.2 0.2 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KKF97067.1 - 6.1e-21 74.6 4.1 5.4e-18 64.9 0.0 2.5 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KKF97067.1 - 7.9e-11 42.2 0.4 1.9e-10 41.0 0.4 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKF97067.1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Aminotran_1_2 PF00155.21 KKF97068.1 - 7.2e-79 265.6 0.0 8.6e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1233 PF06806.12 KKF97068.1 - 0.064 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative excisionase (DUF1233) NIR_SIR PF01077.22 KKF97069.1 - 1.1e-53 181.0 0.0 2e-47 160.6 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 KKF97069.1 - 1.2e-30 106.6 0.0 3.5e-30 105.1 0.0 1.9 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 KKF97069.1 - 1e-27 95.7 0.0 4.5e-13 48.8 0.0 2.9 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 KKF97069.1 - 4.8e-08 33.0 1.0 8.1e-08 32.3 0.2 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.11 KKF97070.1 - 5.9e-09 36.1 0.2 8.6e-09 35.5 0.2 1.3 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Actin PF00022.19 KKF97071.1 - 4.5e-132 440.5 0.0 5.2e-132 440.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKF97071.1 - 0.0047 15.8 0.0 0.32 9.8 0.0 2.4 3 0 0 3 3 3 2 MreB/Mbl protein SRF-TF PF00319.18 KKF97072.1 - 2.2e-23 81.5 0.3 3.3e-23 80.9 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF4611 PF15387.6 KKF97072.1 - 0.061 13.5 1.1 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3591 PF12157.8 KKF97073.1 - 3.8e-172 572.9 0.2 5.3e-172 572.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 KKF97073.1 - 0.0066 16.3 0.7 0.017 14.9 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KKF97073.1 - 0.0096 16.0 0.7 0.0096 16.0 0.7 1.9 2 0 0 2 2 2 1 Zinc knuckle DUF3847 PF12958.7 KKF97073.1 - 0.08 13.1 0.5 0.28 11.3 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) ALAD PF00490.21 KKF97074.1 - 8.7e-122 406.2 0.0 1e-121 406.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase AIM5 PF17050.5 KKF97075.1 - 1.5e-19 70.6 1.6 2e-19 70.1 1.6 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 DUF4041 PF13250.6 KKF97075.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) DUF2105 PF09878.9 KKF97075.1 - 0.2 11.4 0.0 0.27 11.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) Ribosomal_L17 PF01196.19 KKF97076.1 - 3.4e-31 108.0 0.7 6.5e-31 107.1 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 UTP25 PF06862.12 KKF97077.1 - 3.4e-178 593.3 5.8 3e-115 385.7 1.2 2.1 1 1 1 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KKF97077.1 - 0.00024 20.9 0.0 0.006 16.4 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase MitMem_reg PF13012.6 KKF97078.1 - 1.8e-19 70.2 0.2 4.7e-19 68.9 0.2 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KKF97078.1 - 5.9e-14 52.1 0.0 1.4e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4834 PF16118.5 KKF97078.1 - 5.3 8.1 5.2 12 6.9 5.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Rad1 PF02144.16 KKF97081.1 - 1.1e-50 172.2 0.0 1.5e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CENP-B_dimeris PF09026.10 KKF97081.1 - 0.015 15.7 0.0 0.015 15.7 0.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SUIM_assoc PF16619.5 KKF97082.1 - 0.069 13.2 9.8 0.11 12.6 3.7 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PMP1_2 PF08114.11 KKF97084.1 - 0.028 14.1 2.8 0.028 14.1 2.8 1.6 1 1 1 2 2 2 0 ATPase proteolipid family DUF2206 PF09971.9 KKF97084.1 - 0.17 10.6 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) ResB PF05140.14 KKF97084.1 - 0.17 10.6 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 ResB-like family Sec61_beta PF03911.16 KKF97084.1 - 0.94 9.6 4.4 1.2 9.2 4.4 1.2 1 0 0 1 1 1 0 Sec61beta family MFS_MOT1 PF16983.5 KKF97085.1 - 6.4e-55 184.3 37.3 5e-29 100.9 12.5 2.9 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily TipE PF16972.5 KKF97086.1 - 0.88 8.7 8.3 1.8 7.6 8.3 1.4 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Rrn6 PF10214.9 KKF97086.1 - 2.5 6.5 13.1 4.8 5.5 13.1 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor LRR_6 PF13516.6 KKF97086.1 - 7.5 6.9 8.9 53 4.2 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich repeat Ribosomal_L5e PF17144.4 KKF97087.1 - 2.5e-81 271.5 0.2 3.5e-81 271.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KKF97087.1 - 8.5e-35 119.6 2.6 8.5e-35 119.6 2.6 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region GMC_oxred_N PF00732.19 KKF97090.1 - 7.9e-31 107.5 0.0 1.5e-27 96.8 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KKF97090.1 - 3.9e-26 92.3 0.0 6.9e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KKF97090.1 - 0.00016 21.8 0.0 0.00043 20.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKF97090.1 - 0.00019 20.8 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKF97090.1 - 0.0024 17.0 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KKF97090.1 - 0.012 14.9 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KKF97090.1 - 0.013 14.6 0.1 0.018 14.1 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein HHH PF00633.23 KKF97090.1 - 0.015 15.1 0.2 5.1 7.2 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix motif FAD_oxidored PF12831.7 KKF97090.1 - 0.031 13.6 0.4 0.05 12.9 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKF97090.1 - 0.036 13.3 0.0 6.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKF97090.1 - 0.057 12.1 0.1 0.13 10.9 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KKF97090.1 - 0.16 12.5 0.0 0.37 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GlyL_C PF12524.8 KKF97091.1 - 0.027 14.6 0.3 0.1 12.8 0.3 2.0 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal Ribosomal_60s PF00428.19 KKF97091.1 - 0.3 11.7 10.3 0.63 10.7 10.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein TIM PF00121.18 KKF97092.1 - 7.9e-89 297.2 0.5 9e-89 297.0 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase L51_S25_CI-B8 PF05047.16 KKF97093.1 - 1e-13 51.0 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 KKF97094.1 - 4.4e-22 78.5 0.9 7.5e-22 77.8 0.9 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KKF97094.1 - 7.7e-10 38.5 0.1 3.9e-09 36.2 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKF97094.1 - 2.8e-05 24.1 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif FtsX PF02687.21 KKF97094.1 - 4.2 7.9 5.5 1.6 9.2 2.9 1.7 2 0 0 2 2 2 0 FtsX-like permease family RL10P_insert PF17777.1 KKF97095.1 - 1.3e-21 76.3 0.0 2.4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KKF97095.1 - 2e-19 69.6 0.0 2.9e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Fungal_trans PF04082.18 KKF97096.1 - 2.8e-05 23.3 0.0 4.8e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain IQCJ-SCHIP1 PF15157.6 KKF97096.1 - 0.087 12.7 0.3 0.22 11.3 0.3 1.6 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Nt_Gln_amidase PF09764.9 KKF97096.1 - 0.14 11.7 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 N-terminal glutamine amidase Spt20 PF12090.8 KKF97096.1 - 6.4 6.3 12.2 14 5.2 12.3 1.5 1 1 0 1 1 1 0 Spt20 family CMAS PF02353.20 KKF97097.1 - 2.3e-61 207.5 0.0 3e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KKF97097.1 - 2e-11 44.4 0.0 4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKF97097.1 - 2.9e-10 40.7 0.0 6e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF97097.1 - 1.3e-08 34.9 0.0 2.8e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF97097.1 - 0.0013 19.5 0.0 0.0036 18.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KKF97097.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 KKF97097.1 - 0.023 14.5 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KKF97097.1 - 0.035 13.9 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KKF97097.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 KKF97097.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CDH-cyt PF16010.5 KKF97098.1 - 1e-31 110.1 0.0 1e-31 110.1 0.0 1.6 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase Na_H_Exchanger PF00999.21 KKF97100.1 - 8.7e-75 251.9 39.4 9.9e-75 251.7 39.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Phosphodiest PF01663.22 KKF97102.1 - 2.5e-14 53.6 0.1 4.5e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KKF97102.1 - 6.3e-06 25.7 0.8 1.2e-05 24.9 0.8 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KKF97102.1 - 6.6e-06 25.7 0.1 1.2e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 KKF97102.1 - 0.23 11.6 1.4 5.9 6.9 0.2 2.3 2 0 0 2 2 2 0 PglZ domain NTF2 PF02136.20 KKF97103.1 - 2.1e-24 86.4 0.7 3.3e-24 85.7 0.7 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KKF97103.1 - 6.1e-09 35.6 0.2 1.1e-08 34.8 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KKF97103.1 - 0.014 15.5 0.1 0.045 13.8 0.1 1.9 1 0 0 1 1 1 0 RNA binding motif Thymidylat_synt PF00303.19 KKF97104.1 - 1.1e-109 365.7 0.0 1.2e-109 365.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Nnf1 PF03980.14 KKF97105.1 - 1.1e-30 106.3 1.0 1.9e-30 105.4 1.0 1.4 1 0 0 1 1 1 1 Nnf1 TPR_MLP1_2 PF07926.12 KKF97105.1 - 0.0021 18.1 0.4 0.0021 18.1 0.4 1.5 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein MAP65_ASE1 PF03999.12 KKF97105.1 - 0.0086 14.8 0.0 0.0097 14.7 0.0 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) YqjK PF13997.6 KKF97105.1 - 0.035 14.4 1.4 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 YqjK-like protein HIP1_clath_bdg PF16515.5 KKF97105.1 - 0.087 13.4 1.2 0.34 11.6 0.1 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Katanin_con80 PF13925.6 KKF97105.1 - 0.11 12.5 0.4 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 con80 domain of Katanin DUF1640 PF07798.11 KKF97106.1 - 2e-40 138.7 4.8 2.9e-40 138.2 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF2570 PF10828.8 KKF97106.1 - 0.15 11.8 2.6 0.22 11.3 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF2130 PF09903.9 KKF97106.1 - 0.17 11.1 2.9 0.28 10.4 2.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) PUF PF00806.19 KKF97107.1 - 1.9e-50 165.8 3.4 2.1e-06 27.1 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat APH PF01636.23 KKF97108.1 - 3.3e-14 53.4 0.8 4.8e-14 52.9 0.8 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKF97108.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2956 PF11169.8 KKF97109.1 - 3.9 7.7 6.7 0.23 11.7 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2956) Ca_chan_IQ PF08763.11 KKF97110.1 - 0.12 12.5 0.3 6.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain Patatin PF01734.22 KKF97111.1 - 1.6e-16 61.1 0.0 2.9e-16 60.3 0.0 1.4 1 1 0 1 1 1 1 Patatin-like phospholipase CPSase_L_D2 PF02786.17 KKF97112.1 - 4.7e-72 241.9 0.0 7.1e-72 241.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KKF97112.1 - 2e-37 127.6 0.0 4.3e-37 126.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KKF97112.1 - 9.8e-36 122.6 0.0 2.3e-35 121.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KKF97112.1 - 1.8e-13 50.1 0.9 4e-13 49.0 0.5 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.22 KKF97112.1 - 3.8e-07 29.8 0.0 2.3e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KKF97112.1 - 6.6e-06 25.8 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KKF97112.1 - 2.5e-05 24.0 0.1 0.0015 18.3 0.0 2.7 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KKF97112.1 - 0.019 15.7 0.0 15 6.4 0.0 2.9 2 0 0 2 2 2 0 HlyD family secretion protein ATP-grasp_3 PF02655.14 KKF97112.1 - 0.057 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain GCV_H PF01597.19 KKF97112.1 - 0.11 12.4 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein ABC_tran PF00005.27 KKF97113.1 - 2.2e-48 164.3 0.1 3.4e-26 92.4 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KKF97113.1 - 8.2e-14 52.1 4.4 0.0063 16.4 0.3 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKF97113.1 - 6.9e-13 48.5 0.1 0.00015 21.3 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKF97113.1 - 1.4e-08 35.5 0.5 0.00086 19.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain Chromo PF00385.24 KKF97113.1 - 6.1e-08 32.5 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RsgA_GTPase PF03193.16 KKF97113.1 - 1.6e-07 31.4 0.1 0.0023 17.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKF97113.1 - 2.7e-07 30.7 0.0 0.0032 17.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KKF97113.1 - 8.1e-07 28.7 1.2 0.0091 15.7 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KKF97113.1 - 0.00023 21.7 0.0 1 9.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KKF97113.1 - 0.00024 20.9 0.6 0.16 11.6 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KKF97113.1 - 0.00027 21.2 0.4 0.41 10.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KKF97113.1 - 0.0013 19.1 0.1 2 8.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 KKF97113.1 - 0.0017 18.6 0.0 0.051 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KKF97113.1 - 0.0018 18.3 0.0 0.44 10.6 0.0 3.0 3 0 0 3 3 3 1 Dynamin family MeaB PF03308.16 KKF97113.1 - 0.0025 16.8 0.7 0.61 9.0 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KKF97113.1 - 0.0035 17.5 0.0 2.6 8.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKF97113.1 - 0.004 17.1 0.1 2.9 7.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KKF97113.1 - 0.004 16.9 1.3 0.3 10.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KKF97113.1 - 0.0047 17.1 0.0 2.4 8.4 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.9 KKF97113.1 - 0.006 16.3 0.0 0.53 10.0 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 KKF97113.1 - 0.0063 16.3 0.4 2.2 8.0 0.1 3.1 2 0 0 2 2 2 1 AAA domain HEAT PF02985.22 KKF97113.1 - 0.0096 16.1 1.1 14 6.2 0.1 5.2 5 0 0 5 5 5 0 HEAT repeat DUF87 PF01935.17 KKF97113.1 - 0.015 15.4 2.9 0.74 9.9 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain AAA PF00004.29 KKF97113.1 - 0.02 15.3 0.0 5.7 7.4 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HEAT_EZ PF13513.6 KKF97113.1 - 0.022 15.3 1.9 7.5 7.2 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat DUF815 PF05673.13 KKF97113.1 - 0.033 13.4 0.1 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KKF97113.1 - 0.035 13.3 1.0 9.9 5.3 0.1 3.3 3 0 0 3 3 3 0 NB-ARC domain LEH PF07858.12 KKF97113.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain AAA_16 PF13191.6 KKF97113.1 - 0.053 13.9 0.1 1.3 9.4 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 KKF97113.1 - 0.055 13.4 0.2 13 5.7 0.2 3.1 3 0 0 3 3 3 0 NTPase AAA_27 PF13514.6 KKF97113.1 - 0.064 12.8 1.5 6.5 6.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KKF97113.1 - 0.066 12.7 0.1 9.9 5.6 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region Roc PF08477.13 KKF97113.1 - 0.069 13.4 0.1 7 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ALF PF03752.13 KKF97113.1 - 0.071 13.1 0.5 18 5.4 0.1 2.8 2 0 0 2 2 2 0 Short repeats of unknown function AAA_13 PF13166.6 KKF97113.1 - 0.085 11.5 0.0 7.3 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKF97113.1 - 0.1 12.6 0.0 9 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KKF97113.1 - 0.11 11.7 0.0 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Septin TsaE PF02367.17 KKF97113.1 - 0.25 11.3 2.1 21 5.1 0.0 3.2 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Glyco_hydro_3 PF00933.21 KKF97114.1 - 7.2e-43 147.2 0.0 1.1e-42 146.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KKF97114.1 - 9.5e-43 146.5 0.0 1.7e-42 145.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KKF97114.1 - 1.1e-20 73.4 0.0 2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Cwf_Cwc_15 PF04889.12 KKF97114.1 - 1.8 8.3 16.9 2.8 7.6 16.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KKF97114.1 - 2.5 7.3 16.8 3.8 6.8 16.8 1.1 1 0 0 1 1 1 0 NOA36 protein Spc7 PF08317.11 KKF97115.1 - 5e-06 25.6 72.2 0.0021 17.0 7.4 4.3 1 1 3 4 4 4 4 Spc7 kinetochore protein GAS PF13851.6 KKF97115.1 - 1.2e-05 24.7 66.0 0.00049 19.5 24.1 5.0 1 1 4 5 5 5 3 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KKF97115.1 - 0.00025 21.5 67.3 0.0023 18.4 8.6 5.1 1 1 4 5 5 5 3 Fez1 FPP PF05911.11 KKF97115.1 - 0.00026 19.3 59.9 0.0038 15.5 15.9 3.1 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil Golgin_A5 PF09787.9 KKF97115.1 - 0.00043 19.8 60.0 0.0066 15.9 12.6 4.0 1 1 3 4 4 4 2 Golgin subfamily A member 5 DUF4201 PF13870.6 KKF97115.1 - 0.00057 19.7 1.1 0.00057 19.7 1.1 5.6 2 2 2 4 4 3 1 Domain of unknown function (DUF4201) DUF1664 PF07889.12 KKF97115.1 - 0.0023 18.0 39.4 0.02 15.0 1.2 7.2 2 2 5 7 7 7 2 Protein of unknown function (DUF1664) APG6_N PF17675.1 KKF97115.1 - 0.0025 18.3 12.2 0.0025 18.3 12.2 6.6 1 1 5 6 6 6 3 Apg6 coiled-coil region DUF4200 PF13863.6 KKF97115.1 - 0.0034 17.8 19.5 0.0034 17.8 19.5 6.0 3 2 2 5 5 5 2 Domain of unknown function (DUF4200) ATG16 PF08614.11 KKF97115.1 - 0.009 16.3 84.6 4.5 7.4 24.7 5.1 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KKF97115.1 - 0.011 15.8 66.4 0.1 12.6 5.6 6.2 1 1 6 7 7 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KKF97115.1 - 0.012 15.4 3.9 0.012 15.4 3.9 9.5 4 2 6 11 11 11 0 Septum formation initiator TMF_TATA_bd PF12325.8 KKF97115.1 - 0.018 15.3 4.4 0.018 15.3 4.4 6.8 1 1 6 7 7 7 0 TATA element modulatory factor 1 TATA binding CALCOCO1 PF07888.11 KKF97115.1 - 0.06 12.2 68.6 0.035 13.0 34.7 3.1 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like MscS_porin PF12795.7 KKF97115.1 - 0.079 12.5 78.7 0.016 14.8 35.1 4.4 1 1 2 3 3 2 0 Mechanosensitive ion channel porin domain IFT57 PF10498.9 KKF97115.1 - 0.18 10.8 45.1 0.3 10.0 5.5 5.2 1 1 3 4 4 4 0 Intra-flagellar transport protein 57 CCDC144C PF14915.6 KKF97115.1 - 0.21 10.6 65.6 0.72 8.9 20.0 4.5 1 1 0 3 3 3 0 CCDC144C protein coiled-coil region Bap31_Bap29_C PF18035.1 KKF97115.1 - 0.32 11.0 0.0 0.32 11.0 0.0 7.6 7 2 1 8 8 8 0 Bap31/Bap29 cytoplasmic coiled-coil domain FlpD PF02662.16 KKF97115.1 - 0.43 10.6 6.6 3.6 7.6 0.2 3.1 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit AAA_13 PF13166.6 KKF97115.1 - 0.47 9.0 58.0 0.4 9.3 19.4 3.4 1 1 2 3 3 3 0 AAA domain KASH_CCD PF14662.6 KKF97115.1 - 0.47 10.2 64.7 0.099 12.5 13.3 6.0 1 1 4 5 5 5 0 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 KKF97115.1 - 0.56 10.9 56.5 0.24 12.0 1.3 8.7 5 3 4 9 9 9 0 SlyX bMG6 PF17962.1 KKF97115.1 - 0.6 10.3 3.5 0.76 9.9 0.3 2.8 3 0 0 3 3 2 0 Bacterial macroglobulin domain 6 HMMR_N PF15905.5 KKF97115.1 - 1.1 8.7 69.7 0.024 14.1 22.0 4.5 1 1 4 5 5 5 0 Hyaluronan mediated motility receptor N-terminal Exonuc_VII_S PF02609.16 KKF97115.1 - 1.1 9.4 23.1 1.3 9.1 8.4 4.3 3 0 0 3 3 3 0 Exonuclease VII small subunit EzrA PF06160.12 KKF97115.1 - 1.4 7.0 50.0 0.23 9.6 13.1 4.1 1 1 2 4 4 4 0 Septation ring formation regulator, EzrA Rab5-bind PF09311.11 KKF97115.1 - 1.8 7.9 57.9 0.47 9.8 16.6 5.3 2 1 2 4 4 4 0 Rabaptin-like protein DUF4407 PF14362.6 KKF97115.1 - 2.3 7.5 73.3 0.16 11.3 22.3 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Filament PF00038.21 KKF97115.1 - 4.5 6.8 69.8 0.15 11.6 2.5 5.7 1 1 4 5 5 5 0 Intermediate filament protein ADIP PF11559.8 KKF97115.1 - 5.6 7.0 71.6 0.33 11.0 3.6 7.6 2 2 5 7 7 7 0 Afadin- and alpha -actinin-Binding Leu_zip PF15294.6 KKF97115.1 - 6 6.3 60.9 0.067 12.7 0.8 5.2 1 1 3 5 5 5 0 Leucine zipper YabA PF06156.13 KKF97115.1 - 6 7.6 51.7 4.1 8.1 4.3 7.4 3 3 3 6 6 6 0 Initiation control protein YabA Fib_alpha PF08702.10 KKF97115.1 - 9 6.5 34.5 2.3 8.4 7.6 5.2 1 1 3 6 6 6 0 Fibrinogen alpha/beta chain family MAD PF05557.13 KKF97115.1 - 9.4 4.5 59.7 1.3 7.3 28.4 2.7 1 1 1 2 2 2 0 Mitotic checkpoint protein Mem_trans PF03547.18 KKF97116.1 - 1.9e-54 184.6 3.5 9.6e-54 182.2 3.5 1.9 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.25 KKF97117.1 - 1.2e-53 182.2 0.0 1.9e-50 171.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF97117.1 - 4.7e-32 111.3 0.0 8.8e-31 107.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF97117.1 - 1.8e-07 30.8 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KKF97117.1 - 0.01 14.9 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KKF97117.1 - 0.013 14.4 0.1 0.039 12.9 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KKF97117.1 - 0.042 12.6 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KKF97117.1 - 0.069 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 KKF97117.1 - 0.11 12.4 0.0 0.73 9.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Gln-synt_C PF00120.24 KKF97118.1 - 1.9e-81 273.7 0.0 2.3e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KKF97118.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain ERCC4 PF02732.15 KKF97119.1 - 6.7e-20 71.9 0.0 1.6e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain adh_short_C2 PF13561.6 KKF97120.1 - 3.8e-57 193.5 0.3 4.3e-57 193.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKF97120.1 - 4.5e-39 133.9 0.1 5.4e-39 133.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKF97120.1 - 4.8e-09 36.4 1.1 7.5e-09 35.7 1.1 1.3 1 0 0 1 1 1 1 KR domain ChuX_HutX PF06228.13 KKF97120.1 - 0.0057 16.4 0.0 2.3 8.0 0.0 2.4 1 1 1 2 2 2 2 Haem utilisation ChuX/HutX 3HCDH_N PF02737.18 KKF97120.1 - 0.0057 16.6 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KKF97120.1 - 0.016 15.9 0.0 0.034 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.19 KKF97120.1 - 0.046 13.0 0.4 0.24 10.7 0.1 2.2 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KKF97120.1 - 0.088 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 KKF97120.1 - 0.099 12.2 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_16 PF00722.21 KKF97121.1 - 1.7e-40 138.4 0.9 2.9e-40 137.6 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1275 PF06912.11 KKF97122.1 - 3.5e-48 164.1 10.7 4.4e-48 163.8 10.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Ras PF00071.22 KKF97123.1 - 2.8e-51 173.3 0.0 4.8e-51 172.6 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKF97123.1 - 2.8e-21 76.0 0.0 5.2e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF97123.1 - 4.1e-08 32.9 0.0 2.4e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 KKF97123.1 - 0.0082 15.3 0.0 0.012 14.8 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KKF97123.1 - 0.01 15.2 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKF97123.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.10 KKF97123.1 - 0.048 13.1 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KKF97123.1 - 0.048 14.2 0.0 0.079 13.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter BSP_II PF05432.11 KKF97123.1 - 0.062 13.0 3.1 0.089 12.5 3.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sporozoite_P67 PF05642.11 KKF97123.1 - 0.11 10.5 3.1 0.14 10.2 3.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyoxalase_2 PF12681.7 KKF97124.1 - 0.079 12.9 0.0 0.67 9.9 0.0 2.2 2 0 0 2 2 2 0 Glyoxalase-like domain LIAS_N PF16881.5 KKF97125.1 - 2.2e-17 63.4 0.1 7.4e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KKF97125.1 - 6.4e-14 52.7 0.1 1.6e-13 51.4 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Herpes_capsid PF06112.11 KKF97125.1 - 6.9 6.7 10.5 13 5.8 10.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Rox3 PF08633.10 KKF97126.1 - 2.1e-32 113.1 8.9 1.1e-16 61.8 0.0 2.2 1 1 1 2 2 2 2 Rox3 mediator complex subunit RmlD_sub_bind PF04321.17 KKF97127.1 - 1.6e-54 184.9 0.0 2.1e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KKF97127.1 - 6.2e-21 75.0 0.0 7.9e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKF97127.1 - 2e-10 40.6 0.3 1.1e-09 38.2 0.3 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KKF97127.1 - 3.7e-09 36.1 1.7 1.8e-06 27.3 0.1 3.6 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KKF97127.1 - 1.8e-08 33.9 0.4 6.7e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KKF97127.1 - 3.1e-07 29.7 0.1 1.7e-06 27.3 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KKF97127.1 - 0.0067 16.3 1.2 0.018 15.0 1.2 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KKF97127.1 - 0.028 14.0 1.8 0.14 11.7 0.8 2.2 2 1 0 2 2 2 0 NmrA-like family KR PF08659.10 KKF97127.1 - 0.19 11.7 2.9 7 6.5 2.0 2.9 2 1 0 2 2 2 0 KR domain polyprenyl_synt PF00348.17 KKF97128.1 - 6.7e-90 300.6 0.0 8.9e-90 300.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase PgdA_N PF18627.1 KKF97128.1 - 0.09 12.4 0.5 0.25 11.0 0.1 1.8 2 0 0 2 2 2 0 Peptidoglycan GlcNAc deacetylase N-terminal domain ANAPC8 PF04049.13 KKF97129.1 - 9.5e-56 187.7 0.0 2e-55 186.7 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KKF97129.1 - 4.3e-22 77.0 4.9 9.6e-05 22.0 0.0 7.1 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KKF97129.1 - 4.9e-19 66.9 9.9 7.3e-05 22.7 0.0 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKF97129.1 - 6.7e-15 53.9 15.9 0.031 14.4 0.1 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 KKF97129.1 - 3.1e-10 39.6 3.2 1.2e-06 28.1 0.1 4.2 2 2 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 KKF97129.1 - 4.5e-10 39.5 15.0 0.006 17.3 0.1 8.2 6 2 3 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF97129.1 - 8.8e-08 32.3 12.5 0.047 13.9 0.3 5.8 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KKF97129.1 - 1.4e-07 32.1 18.7 2.1e-05 25.0 0.1 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKF97129.1 - 5e-07 29.8 11.4 0.051 13.7 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKF97129.1 - 2.1e-06 27.4 9.8 0.034 14.2 0.0 6.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKF97129.1 - 2.5e-06 27.7 22.2 0.19 12.1 0.1 6.6 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KKF97129.1 - 3e-05 24.4 7.9 1.1 9.8 0.0 5.9 5 2 1 6 6 6 3 Tetratricopeptide repeat DUF3856 PF12968.7 KKF97129.1 - 0.00025 21.1 0.9 0.02 14.9 0.1 2.8 1 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 KKF97129.1 - 0.0042 17.4 0.0 6.4 7.4 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKF97129.1 - 0.021 15.4 13.1 74 4.3 0.9 8.2 8 1 1 9 9 8 0 Tetratricopeptide repeat Vps54 PF07928.12 KKF97132.1 - 6e-45 153.0 0.0 1.6e-44 151.6 0.0 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.9 KKF97132.1 - 2e-06 27.8 0.1 5.6e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KKF97132.1 - 0.0015 17.9 0.1 0.0036 16.6 0.0 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Sec8_exocyst PF04048.14 KKF97132.1 - 0.049 13.5 1.2 0.48 10.3 0.1 2.9 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain TMF_TATA_bd PF12325.8 KKF97132.1 - 0.055 13.7 0.6 0.35 11.1 0.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding MCM PF00493.23 KKF97133.1 - 7.6e-103 342.4 0.0 1.2e-102 341.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKF97133.1 - 5.5e-37 126.4 0.7 1e-36 125.5 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKF97133.1 - 6.4e-27 93.8 2.9 1.5e-26 92.6 2.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKF97133.1 - 2.4e-13 50.5 0.0 6.5e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 KKF97133.1 - 7e-07 29.3 0.0 1.7e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KKF97133.1 - 1.6e-06 27.7 0.0 0.00016 21.1 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KKF97133.1 - 0.00027 20.8 0.0 0.00097 19.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KKF97133.1 - 0.029 14.8 0.1 0.34 11.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKF97133.1 - 0.063 13.0 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 KKF97133.1 - 0.22 11.9 2.2 1.8 8.9 0.2 2.9 2 1 0 2 2 2 0 AAA ATPase domain ANAPC3 PF12895.7 KKF97134.1 - 6.9e-28 96.7 19.8 1.5e-23 82.8 0.8 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KKF97134.1 - 1e-25 88.4 7.4 5.6e-06 25.9 0.7 8.4 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KKF97134.1 - 8e-24 81.8 16.9 0.00067 19.6 0.5 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 KKF97134.1 - 1e-18 65.9 0.8 0.0013 18.8 0.1 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKF97134.1 - 1.8e-17 63.6 21.5 0.052 14.1 0.0 7.5 5 2 2 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 KKF97134.1 - 1.6e-14 53.9 14.8 1.8e-06 28.1 0.0 8.0 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKF97134.1 - 9.3e-14 51.0 17.2 0.17 12.8 0.3 9.6 7 2 3 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKF97134.1 - 2.4e-10 39.9 9.9 0.069 12.8 0.1 6.8 8 1 1 9 9 7 4 TPR repeat TPR_7 PF13176.6 KKF97134.1 - 6.4e-10 38.3 9.3 0.0013 18.6 0.2 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 KKF97134.1 - 1.1e-08 34.6 2.2 0.021 14.7 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKF97134.1 - 1.1e-08 35.0 6.6 7.6e-06 26.0 1.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKF97134.1 - 8.5e-08 32.7 21.5 0.00018 22.1 1.8 8.0 6 3 2 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKF97134.1 - 2e-06 28.1 10.7 2.6 8.8 0.1 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 KKF97134.1 - 0.00011 21.5 10.2 2.5 7.2 0.2 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat DUF3856 PF12968.7 KKF97134.1 - 0.013 15.5 0.6 9.9 6.2 0.0 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 KKF97134.1 - 0.031 14.3 4.2 17 5.6 0.0 5.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 KKF97134.1 - 0.051 13.3 8.9 0.17 11.6 0.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 KKF97134.1 - 0.058 13.4 3.8 5.1 7.1 0.0 4.1 3 1 1 4 4 4 0 Putative TPR-like repeat TPR_17 PF13431.6 KKF97134.1 - 0.079 13.4 3.3 78 4.0 0.0 5.7 7 1 1 8 8 4 0 Tetratricopeptide repeat Sel1 PF08238.12 KKF97134.1 - 0.082 13.6 1.2 23 5.8 0.1 3.7 3 0 0 3 3 3 0 Sel1 repeat SIX1_SD PF16878.5 KKF97134.1 - 0.17 12.4 1.7 2.9 8.4 0.3 2.5 2 0 0 2 2 2 0 Transcriptional regulator, SIX1, N-terminal SD domain Atrophin-1 PF03154.15 KKF97134.1 - 0.24 9.6 0.6 0.36 9.1 0.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.6 KKF97134.1 - 0.32 11.0 3.2 0.7 9.9 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Fis1_TPR_C PF14853.6 KKF97134.1 - 4.2 7.5 5.3 28 4.9 0.1 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat FAM27 PF15832.5 KKF97134.1 - 7.3 7.2 15.7 19 5.9 0.8 2.4 2 0 0 2 2 2 0 FAM27 D and E protein family PhoLip_ATPase_C PF16212.5 KKF97136.1 - 5.6e-52 177.0 10.4 5.6e-52 177.0 10.4 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKF97136.1 - 4.8e-16 58.2 0.2 1.2e-15 56.9 0.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KKF97136.1 - 7.3e-12 46.0 2.3 5.2e-06 26.9 1.3 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KKF97136.1 - 4.1e-07 29.7 1.3 7.6e-06 25.6 1.3 2.7 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KKF97136.1 - 4.1e-06 26.8 0.0 0.00021 21.3 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKF97136.1 - 0.003 17.3 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rep_fac_C PF08542.11 KKF97137.1 - 7.9e-24 83.9 0.0 3.2e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KKF97137.1 - 2.8e-12 46.7 0.0 5.3e-09 36.1 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KKF97137.1 - 9.1e-12 45.5 0.0 1.8e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKF97137.1 - 3.4e-07 30.3 0.0 7.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKF97137.1 - 2.2e-06 28.2 0.1 0.00022 21.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KKF97137.1 - 1.8e-05 24.6 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KKF97137.1 - 1.9e-05 24.9 0.3 0.1 12.9 0.1 2.5 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KKF97137.1 - 0.00016 21.5 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KKF97137.1 - 0.00018 21.4 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KKF97137.1 - 0.00088 19.1 0.1 0.0014 18.4 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KKF97137.1 - 0.0012 18.2 0.0 0.012 15.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKF97137.1 - 0.0017 18.3 0.1 0.015 15.3 0.0 2.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) TniB PF05621.11 KKF97137.1 - 0.0026 17.2 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein AAA_24 PF13479.6 KKF97137.1 - 0.0027 17.5 0.0 0.0067 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KKF97137.1 - 0.003 17.5 0.0 0.0068 16.3 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 KKF97137.1 - 0.0051 16.6 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KKF97137.1 - 0.0053 15.8 0.0 0.01 14.8 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DEAD PF00270.29 KKF97137.1 - 0.0055 16.5 0.2 0.38 10.5 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_assoc_2 PF16193.5 KKF97137.1 - 0.0066 16.8 0.0 0.028 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA C-terminal domain AAA_19 PF13245.6 KKF97137.1 - 0.008 16.5 0.4 0.029 14.7 0.4 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KKF97137.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ NTPase_1 PF03266.15 KKF97137.1 - 0.028 14.3 0.5 0.12 12.3 0.2 2.1 1 1 1 2 2 2 0 NTPase AAA_28 PF13521.6 KKF97137.1 - 0.032 14.5 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKF97137.1 - 0.046 13.3 0.1 0.19 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 KKF97137.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.18 KKF97137.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KKF97137.1 - 0.088 12.5 0.1 0.24 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKF97137.1 - 0.097 13.2 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF3539 PF12058.8 KKF97138.1 - 0.0082 16.3 0.1 0.011 15.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3539) DER1 PF04511.15 KKF97139.1 - 6.2e-11 42.6 2.1 1.6e-07 31.4 0.2 2.0 1 1 1 2 2 2 2 Der1-like family DAP10 PF07213.11 KKF97140.1 - 0.095 12.7 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 DAP10 membrane protein DUF3446 PF11928.8 KKF97140.1 - 4.8 7.6 11.0 1.7 9.0 5.7 2.4 2 1 0 2 2 2 0 Early growth response N-terminal domain CN_hydrolase PF00795.22 KKF97142.1 - 3e-15 56.3 0.0 5.4e-15 55.4 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Pkinase PF00069.25 KKF97143.1 - 5.6e-22 78.4 0.0 2.4e-11 43.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF97143.1 - 0.00026 20.3 0.1 0.44 9.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase DKCLD PF08068.12 KKF97144.1 - 7.4e-32 109.2 0.4 1.5e-30 105.0 0.5 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KKF97144.1 - 3.3e-22 78.4 0.7 6.6e-22 77.4 0.7 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KKF97144.1 - 3.5e-22 78.2 1.0 7.3e-22 77.1 1.0 1.6 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 KKF97144.1 - 4.3e-22 79.1 0.1 6.7e-19 68.7 0.1 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 KKF97144.1 - 0.00095 19.4 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain NAM-associated PF14303.6 KKF97144.1 - 0.72 10.5 16.8 1.2 9.8 16.8 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Med19 PF10278.9 KKF97144.1 - 2.6 7.9 10.0 5.8 6.8 10.0 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 KKF97144.1 - 9.2 6.0 10.4 13 5.5 10.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-MYND PF01753.18 KKF97145.1 - 2.2e-06 27.7 10.1 2.2e-06 27.7 10.1 2.0 2 0 0 2 2 2 1 MYND finger Rubredoxin_2 PF18073.1 KKF97145.1 - 0.12 12.2 2.3 0.44 10.3 2.3 2.0 1 0 0 1 1 1 0 Rubredoxin metal binding domain DUF3762 PF12591.8 KKF97147.1 - 0.6 10.4 3.3 2 8.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3762) CRAL_TRIO PF00650.20 KKF97148.1 - 2.2e-16 60.0 0.0 2.9e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKF97148.1 - 0.00024 21.2 0.0 0.00056 20.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SET PF00856.28 KKF97149.1 - 3.8e-14 53.4 0.4 3.8e-14 53.4 0.4 3.8 2 2 1 3 3 3 1 SET domain AWS PF17907.1 KKF97149.1 - 4e-08 33.1 5.4 9.6e-08 31.9 5.4 1.7 1 0 0 1 1 1 1 AWS domain EI24 PF07264.11 KKF97150.1 - 1.3e-08 35.3 7.4 7.1e-07 29.6 7.4 2.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) 2OG-FeII_Oxy PF03171.20 KKF97150.1 - 0.0004 20.8 0.0 0.00095 19.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KKF97150.1 - 0.0012 19.6 0.0 0.013 16.2 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal SKG6 PF08693.10 KKF97150.1 - 4.2 6.8 8.2 0.12 11.8 1.4 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Acetyltransf_9 PF13527.7 KKF97151.1 - 1.4e-07 31.6 0.1 3.1e-07 30.5 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKF97151.1 - 3.9e-05 24.0 0.0 6.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKF97151.1 - 6.7e-05 22.8 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKF97151.1 - 0.00035 20.5 0.0 0.00092 19.1 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KKF97151.1 - 0.00061 20.0 0.1 0.0012 19.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 KKF97151.1 - 0.071 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Glyco_transf_28 PF03033.20 KKF97152.1 - 3.1e-29 101.8 0.0 5.9e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KKF97152.1 - 9e-26 90.0 0.6 6.1e-21 74.4 0.0 2.4 2 0 0 2 2 2 2 GRAM domain PH PF00169.29 KKF97152.1 - 3e-08 34.1 0.0 1.1e-07 32.3 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KKF97152.1 - 0.0013 18.9 0.0 0.035 14.4 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.18 KKF97152.1 - 0.0066 15.3 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.6 KKF97152.1 - 0.014 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 PH domain PH_2 PF08458.10 KKF97152.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.7 2 0 0 2 2 2 0 Plant pleckstrin homology-like region WD40 PF00400.32 KKF97153.1 - 2.1e-09 37.8 5.8 0.12 13.3 0.3 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat HrpB4 PF09502.10 KKF97154.1 - 0.047 13.5 1.5 0.057 13.3 0.1 1.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB4) NIF PF03031.18 KKF97155.1 - 9.3e-27 93.7 0.0 1.9e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KKF97155.1 - 7.6e-06 26.2 0.0 1.8e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KKF97155.1 - 0.00016 21.6 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 KKF97155.1 - 0.00021 21.1 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KKF97155.1 - 0.0031 17.9 0.0 0.0072 16.7 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Biotin_lipoyl_2 PF13533.6 KKF97155.1 - 0.029 14.2 0.0 0.99 9.3 0.0 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like VIT1 PF01988.19 KKF97156.1 - 4.3e-70 235.9 4.4 5.1e-70 235.7 4.4 1.1 1 0 0 1 1 1 1 VIT family Orai-1 PF07856.12 KKF97156.1 - 0.12 12.0 3.2 0.2 11.3 3.2 1.4 1 1 0 1 1 1 0 Mediator of CRAC channel activity DUF2370 PF10176.9 KKF97157.1 - 2.8e-83 279.0 0.0 4.4e-83 278.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Mito_carr PF00153.27 KKF97159.1 - 2.1e-50 168.6 4.8 5.2e-21 74.4 0.3 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein PP-binding PF00550.25 KKF97160.1 - 1.1e-11 44.9 0.1 1.5e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KKF97160.1 - 2.4e-05 24.5 0.1 3e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier AA_permease PF00324.21 KKF97161.1 - 4.6e-104 348.7 44.9 4e-98 329.1 29.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKF97161.1 - 8e-27 94.1 30.8 8e-27 94.1 30.8 2.2 1 1 1 2 2 2 1 Amino acid permease DUF3098 PF11297.8 KKF97161.1 - 0.2 11.3 7.0 2.7 7.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) DUF389 PF04087.14 KKF97161.1 - 3.1 7.8 12.9 1.1 9.3 0.8 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF389) zf_CCCH_4 PF18345.1 KKF97162.1 - 0.078 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Zinc finger domain DUF1857 PF08982.11 KKF97164.1 - 2e-39 134.8 0.0 2.2e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Ion_trans_2 PF07885.16 KKF97165.1 - 1.3e-32 111.6 24.9 2.3e-19 69.1 3.4 3.0 3 0 0 3 3 3 2 Ion channel FBPase PF00316.20 KKF97165.1 - 9.7e-23 80.6 0.0 1.8e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Ion_trans PF00520.31 KKF97165.1 - 0.00024 20.4 16.1 0.00029 20.2 3.7 2.7 2 1 1 3 3 3 2 Ion transport protein Inositol_P PF00459.25 KKF97165.1 - 0.054 13.0 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family Fungal_trans_2 PF11951.8 KKF97166.1 - 1.9e-07 30.2 2.6 1e-06 27.9 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_38 PF18438.1 KKF97166.1 - 0.025 14.6 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 TonB_N PF16031.5 KKF97166.1 - 6.4 7.3 16.5 0.11 13.0 9.2 1.8 2 0 0 2 2 2 0 TonB polyproline region Sporozoite_P67 PF05642.11 KKF97166.1 - 7.1 4.6 7.2 14 3.6 7.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_61 PF03443.14 KKF97168.1 - 1.7e-53 181.7 0.0 2.7e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Transp_cyt_pur PF02133.15 KKF97169.1 - 1.8e-87 294.0 30.5 2.2e-87 293.7 30.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_hydro_61 PF03443.14 KKF97170.1 - 4e-53 180.4 0.1 5.9e-53 179.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4106 PF13388.6 KKF97170.1 - 0.28 10.4 12.8 0.41 9.8 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CAP_GLY PF01302.25 KKF97171.1 - 1.2e-08 34.9 3.4 3e-08 33.6 3.4 1.7 1 0 0 1 1 1 1 CAP-Gly domain Filament PF00038.21 KKF97171.1 - 3.9e-07 30.0 20.2 3.3e-05 23.6 4.8 2.3 2 0 0 2 2 2 2 Intermediate filament protein CLIP1_ZNF PF16641.5 KKF97171.1 - 5.5e-07 29.3 16.6 0.0012 18.7 1.7 3.4 3 0 0 3 3 3 2 CLIP1 zinc knuckle AAA_13 PF13166.6 KKF97171.1 - 0.0028 16.4 10.9 0.0028 16.4 10.9 2.0 2 0 0 2 2 2 1 AAA domain Med4 PF10018.9 KKF97171.1 - 0.013 15.2 2.1 0.013 15.2 2.1 3.2 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF812 PF05667.11 KKF97171.1 - 0.032 13.1 28.8 0.087 11.7 18.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF812) NPV_P10 PF05531.12 KKF97171.1 - 0.062 13.8 11.6 0.88 10.1 0.8 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 KKF97171.1 - 0.22 11.7 20.0 1.2 9.3 5.0 3.8 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family DHR10 PF18595.1 KKF97171.1 - 0.26 11.4 39.3 0.049 13.7 8.7 4.0 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain Lipoprotein_7 PF01540.16 KKF97171.1 - 0.36 10.1 4.2 0.6 9.3 4.2 1.3 1 0 0 1 1 1 0 Adhesin lipoprotein Phage_GP20 PF06810.11 KKF97171.1 - 0.93 9.3 21.2 2.8 7.7 4.9 3.6 3 1 1 4 4 4 0 Phage minor structural protein GP20 Glutaredoxin2_C PF04399.13 KKF97171.1 - 0.98 9.3 8.8 0.54 10.1 0.5 2.7 3 0 0 3 3 2 0 Glutaredoxin 2, C terminal domain C1_2 PF03107.16 KKF97171.1 - 1.1 9.6 3.1 25 5.3 0.2 2.4 2 0 0 2 2 2 0 C1 domain Prominin PF05478.11 KKF97171.1 - 1.4 6.8 5.7 0.7 7.8 2.9 1.5 1 1 0 1 1 1 0 Prominin zf-CCHC_4 PF14392.6 KKF97171.1 - 1.9 8.3 3.2 18 5.2 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle Fez1 PF06818.15 KKF97171.1 - 3.3 8.1 33.6 0.48 10.9 14.3 3.4 1 1 3 4 4 4 0 Fez1 HemX PF04375.14 KKF97171.1 - 3.4 6.9 21.5 0.017 14.4 2.4 3.0 2 1 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Med9 PF07544.13 KKF97171.1 - 6.5 6.9 17.6 0.44 10.7 0.7 4.4 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Spc7 PF08317.11 KKF97171.1 - 7.1 5.4 30.4 1.8 7.4 6.3 3.3 2 1 0 3 3 3 0 Spc7 kinetochore protein Pkinase PF00069.25 KKF97172.1 - 1.7e-25 89.9 0.0 5.3e-20 71.9 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF97172.1 - 2.1e-09 37.0 0.0 5.9e-08 32.3 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKF97172.1 - 0.00043 20.3 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family TFIIF_alpha PF05793.12 KKF97172.1 - 0.046 12.3 8.1 0.064 11.8 8.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FXMR_C2 PF16098.5 KKF97172.1 - 2 8.9 7.8 48 4.6 2.2 3.5 3 1 0 3 3 3 0 Fragile X-related mental retardation protein C-terminal region 2 Glyco_hydro_38N PF01074.22 KKF97173.1 - 1.6e-87 293.6 2.1 1.6e-87 293.6 2.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KKF97173.1 - 4.1e-41 141.4 2.0 3e-40 138.6 0.5 2.7 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KKF97173.1 - 1.3e-26 92.6 0.0 3.1e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_57 PF03065.15 KKF97173.1 - 0.00055 19.2 0.1 0.0017 17.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Cwf_Cwc_15 PF04889.12 KKF97174.1 - 0.0095 15.7 14.7 0.0093 15.7 14.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MPP6 PF10175.9 KKF97174.1 - 0.033 14.7 0.8 0.036 14.6 0.8 1.2 1 0 0 1 1 1 0 M-phase phosphoprotein 6 DUF2457 PF10446.9 KKF97174.1 - 0.041 13.0 15.4 0.046 12.9 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 KKF97174.1 - 0.044 13.5 4.5 0.072 12.7 4.5 1.4 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 KKF97174.1 - 0.23 10.9 9.6 0.22 10.9 9.6 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KKF97174.1 - 0.23 9.6 11.2 0.2 9.8 11.2 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KKF97174.1 - 0.31 10.6 7.8 0.31 10.6 7.8 1.2 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 KKF97174.1 - 0.31 10.3 9.5 0.32 10.3 9.5 1.1 1 0 0 1 1 1 0 BUD22 LAT PF15234.6 KKF97174.1 - 0.31 10.7 8.6 0.45 10.2 8.6 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells NOA36 PF06524.12 KKF97174.1 - 0.55 9.5 16.8 0.74 9.1 16.8 1.1 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.13 KKF97174.1 - 0.75 9.9 10.2 0.73 9.9 10.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KKF97174.1 - 2.3 6.4 8.3 2.5 6.3 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KKF97174.1 - 4.2 5.4 23.0 5.1 5.1 23.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KKF97174.1 - 4.7 5.6 11.1 5.3 5.5 11.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 KKF97174.1 - 5.4 6.1 12.0 5.3 6.1 12.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Ribosomal_L10 PF00466.20 KKF97175.1 - 1.2e-23 83.1 0.0 3e-23 81.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 KKF97175.1 - 5.2e-23 81.4 4.7 5.2e-23 81.4 4.7 2.1 3 0 0 3 3 3 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 KKF97175.1 - 4e-22 78.0 0.0 8e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P CPSF_A PF03178.15 KKF97176.1 - 0.0065 15.8 0.0 0.031 13.6 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region FixS PF03597.15 KKF97176.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type GFRP PF06399.13 KKF97176.1 - 0.22 11.4 0.4 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) NAD_binding_5 PF07994.12 KKF97177.1 - 5.5e-147 489.3 0.0 7e-147 489.0 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KKF97177.1 - 1.9e-45 153.6 0.4 4.1e-45 152.5 0.4 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Nucleoporin2 PF04096.14 KKF97178.1 - 4.8e-51 172.8 0.0 7.2e-51 172.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KKF97178.1 - 2.2e-15 57.3 168.8 8.8e-09 36.1 26.4 5.9 2 2 4 6 6 6 5 Nucleoporin FG repeat region ICL PF00463.21 KKF97180.1 - 3.3e-288 956.4 2.5 3.8e-288 956.3 2.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Trehalase PF01204.18 KKF97181.1 - 1.9e-192 640.6 0.0 2.3e-192 640.4 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KKF97181.1 - 5.4e-17 61.2 1.1 9e-17 60.5 1.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain PNGaseA PF12222.8 KKF97182.1 - 7.6e-162 539.1 1.6 1e-161 538.6 1.6 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.13 KKF97182.1 - 2.7e-11 43.9 0.0 8.9e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) LEA_4 PF02987.16 KKF97182.1 - 0.071 13.2 0.7 0.16 12.1 0.7 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein Hint PF01079.20 KKF97182.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Hint module MARVEL PF01284.23 KKF97183.1 - 6.5e-17 61.9 14.6 7.5e-17 61.7 14.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF2507 PF10702.9 KKF97184.1 - 0.04 13.8 0.4 0.059 13.3 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2507) eIF-5_eIF-2B PF01873.17 KKF97185.1 - 3.1e-42 143.1 0.4 4.6e-42 142.6 0.4 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KKF97185.1 - 0.018 14.5 0.9 0.038 13.5 0.9 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding SAS4 PF15460.6 KKF97187.1 - 2.6e-29 101.2 0.2 4.2e-29 100.5 0.2 1.4 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Peptidase_M1_N PF17900.1 KKF97188.1 - 6.3e-06 26.5 0.0 0.00045 20.5 0.0 2.8 3 0 0 3 3 3 2 Peptidase M1 N-terminal domain Cation_efflux PF01545.21 KKF97189.1 - 1.1e-46 159.1 23.0 3.7e-46 157.4 23.0 1.7 1 1 0 1 1 1 1 Cation efflux family DUF2157 PF09925.9 KKF97189.1 - 0.0067 16.2 2.1 0.26 11.1 0.0 2.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2157) Macoilin PF09726.9 KKF97189.1 - 2.4 6.6 7.2 3.7 6.0 7.2 1.3 1 0 0 1 1 1 0 Macoilin family Glycoprotein_G PF00802.19 KKF97189.1 - 3.1 7.1 8.6 4.3 6.6 5.7 2.1 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G bZIP_1 PF00170.21 KKF97190.1 - 0.058 13.5 3.8 0.11 12.7 3.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor eIF-3_zeta PF05091.12 KKF97191.1 - 3.2e-204 679.7 0.0 4e-204 679.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sulfate_transp PF00916.20 KKF97192.1 - 1.5e-106 356.4 19.1 2e-106 356.0 19.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KKF97192.1 - 9.8e-09 34.9 0.0 1.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KKF97192.1 - 2.5 8.5 17.8 0.044 14.2 5.4 3.0 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily RabGAP-TBC PF00566.18 KKF97193.1 - 1.8e-29 103.0 0.0 1e-24 87.4 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain HlyIII PF03006.20 KKF97194.1 - 4.6e-56 190.0 21.1 5.7e-56 189.7 21.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ead_Ea22 PF13935.6 KKF97194.1 - 0.11 13.2 6.1 3.9 8.1 2.3 2.2 1 1 1 2 2 2 0 Ead/Ea22-like protein Ubiq_cyt_C_chap PF03981.12 KKF97194.1 - 0.14 12.2 0.7 0.29 11.2 0.7 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone DotU PF09850.9 KKF97194.1 - 0.35 10.6 3.0 0.6 9.8 0.5 2.2 1 1 1 2 2 2 0 Type VI secretion system protein DotU FmiP_Thoc5 PF09766.9 KKF97195.1 - 2.2e-32 112.8 11.3 3.1e-32 112.3 11.3 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 KKF97195.1 - 0.0047 17.0 3.1 0.0047 17.0 3.1 2.3 2 1 0 2 2 2 1 Spermatogenesis-associated C-terminus ETF PF01012.21 KKF97195.1 - 0.0066 16.4 0.4 0.0098 15.8 0.4 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain SKA2 PF16740.5 KKF97195.1 - 0.0077 16.0 1.6 0.0077 16.0 1.6 2.5 2 1 0 2 2 2 1 Spindle and kinetochore-associated protein 2 CENP-F_leu_zip PF10473.9 KKF97195.1 - 0.017 15.1 8.3 0.22 11.5 0.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 KKF97195.1 - 0.14 11.5 8.2 0.19 11.0 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cortex-I_coil PF09304.10 KKF97195.1 - 0.58 10.4 12.2 2.4 8.4 3.8 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil YabA PF06156.13 KKF97195.1 - 2 9.1 9.6 2.2 9.0 1.5 2.7 2 1 1 3 3 3 0 Initiation control protein YabA DUF349 PF03993.12 KKF97195.1 - 2.8 8.3 12.9 0.13 12.6 6.1 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) ZapB PF06005.12 KKF97195.1 - 3.3 8.2 15.9 12 6.5 4.7 2.8 2 1 0 2 2 2 0 Cell division protein ZapB Casc1_N PF15927.5 KKF97195.1 - 3.4 7.3 16.0 0.036 13.8 5.0 2.4 2 1 1 3 3 3 0 Cancer susceptibility candidate 1 N-terminus DUF2175 PF09943.9 KKF97195.1 - 3.5 8.0 5.3 1.2 9.4 0.3 2.4 2 2 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) NPL PF17800.1 KKF97196.1 - 1e-31 109.6 1.5 1e-31 109.6 1.5 2.6 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 KKF97196.1 - 2.9e-29 101.2 0.0 7.9e-29 99.8 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2252 PF10009.9 KKF97196.1 - 0.48 9.4 4.3 0.92 8.5 4.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) BSP_II PF05432.11 KKF97196.1 - 5 6.7 35.6 2 8.0 11.9 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) NifU_N PF01592.16 KKF97197.1 - 8.7e-53 177.9 0.0 1.3e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DUF3870 PF12986.7 KKF97197.1 - 0.077 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) MDM31_MDM32 PF08118.11 KKF97198.1 - 2.4e-155 518.2 0.0 3.1e-155 517.8 0.0 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins DUF957 PF06117.11 KKF97198.1 - 0.026 14.1 0.2 0.077 12.6 0.1 1.8 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) KH_8 PF17903.1 KKF97199.1 - 0.00015 21.8 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KKF97199.1 - 0.068 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 KH domain MRP-L20 PF12824.7 KKF97200.1 - 1.8e-53 181.1 3.4 2.1e-53 180.8 3.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KKF97200.1 - 0.0026 17.8 0.4 0.0045 17.0 0.0 1.6 2 0 0 2 2 2 1 Neugrin HTH_11 PF08279.12 KKF97200.1 - 0.097 12.6 0.0 0.76 9.8 0.0 2.4 3 0 0 3 3 3 0 HTH domain FYVE PF01363.21 KKF97201.1 - 3.5 7.8 16.6 0.14 12.3 9.2 2.3 2 0 0 2 2 2 0 FYVE zinc finger FYVE_2 PF02318.16 KKF97201.1 - 5.4 7.3 9.7 7.8 6.8 3.4 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger FCH PF00611.23 KKF97202.1 - 3.7e-24 84.8 2.7 8.4e-24 83.7 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KKF97202.1 - 3.1e-15 55.8 0.1 1.5e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 KKF97202.1 - 1.4e-14 53.7 5.7 2.2e-14 53.1 5.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 KKF97202.1 - 1e-11 44.2 0.0 2e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 SH3 domain Allexi_40kDa PF05549.11 KKF97202.1 - 0.018 14.6 1.5 0.061 12.8 0.0 2.3 2 1 0 2 2 2 0 Allexivirus 40kDa protein SH3_10 PF17902.1 KKF97202.1 - 0.11 12.6 0.0 0.84 9.8 0.0 2.5 3 0 0 3 3 3 0 SH3 domain C1_2 PF03107.16 KKF97202.1 - 0.26 11.7 4.9 0.46 10.8 4.9 1.4 1 0 0 1 1 1 0 C1 domain USP8_interact PF08941.10 KKF97202.1 - 0.63 9.8 5.6 3.5 7.4 0.0 3.2 3 0 0 3 3 3 0 USP8 interacting FapA PF03961.13 KKF97202.1 - 2.3 6.8 11.1 1.7 7.2 4.4 2.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A COG2 PF06148.11 KKF97202.1 - 7.8 6.6 9.6 4.7 7.3 1.5 2.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DEAD PF00270.29 KKF97203.1 - 2.1e-34 118.8 0.0 4e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF97203.1 - 1.1e-25 90.1 0.0 2.6e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF97203.1 - 1.8e-06 28.1 0.0 2.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KKF97203.1 - 0.011 15.2 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KKF97203.1 - 0.019 15.2 0.4 0.47 10.7 0.5 2.7 2 1 0 2 2 2 0 AAA domain ketoacyl-synt PF00109.26 KKF97205.1 - 5.7e-77 258.7 0.0 1.3e-76 257.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KKF97205.1 - 8.6e-68 228.6 2.2 1.2e-67 228.1 0.1 2.4 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KKF97205.1 - 8.4e-43 147.1 0.0 1.5e-42 146.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKF97205.1 - 1.4e-36 125.1 0.9 5.8e-36 123.1 0.2 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KKF97205.1 - 1.2e-23 84.4 0.0 1.7e-22 80.7 0.0 2.8 3 0 0 3 3 3 1 Thioesterase domain PP-binding PF00550.25 KKF97205.1 - 2.6e-20 72.5 1.9 2.7e-11 43.7 0.1 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.6 KKF97205.1 - 5.9e-18 65.1 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 KKF97205.1 - 5.8e-06 27.1 0.5 0.024 15.2 0.0 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.23 KKF97205.1 - 0.00017 21.1 0.2 0.0011 18.4 0.1 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KKF97205.1 - 0.00022 21.7 0.1 0.00091 19.7 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Hydrolase_4 PF12146.8 KKF97205.1 - 0.035 13.4 0.0 0.81 8.9 0.0 2.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Zn_clus PF00172.18 KKF97206.1 - 1.2e-08 34.9 6.4 1.2e-08 34.9 6.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KKF97207.1 - 1.5e-51 175.3 0.0 2.5e-51 174.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKF97207.1 - 2e-47 161.2 0.4 2.7e-47 160.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKF97207.1 - 5.9e-11 42.6 0.1 7.8e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KKF97207.1 - 0.15 12.0 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KKF97207.1 - 0.48 10.5 2.8 1.2 9.2 2.8 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain zf-C2H2 PF00096.26 KKF97208.1 - 1e-07 32.0 16.8 0.00013 22.2 1.5 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 KKF97208.1 - 3.9e-05 22.8 2.0 0.00073 18.6 0.8 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF97208.1 - 0.00028 20.9 11.5 0.00028 20.9 11.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KKF97208.1 - 0.0093 16.4 14.0 0.014 15.8 4.3 3.7 3 0 0 3 3 3 1 Zinc-finger double domain FMN_dh PF01070.18 KKF97208.1 - 0.031 13.3 3.4 0.078 12.0 2.6 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase zf-C2H2_4 PF13894.6 KKF97208.1 - 0.042 14.7 1.2 0.042 14.7 1.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKF97208.1 - 0.095 13.0 1.6 0.55 10.6 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4230 PF14014.6 KKF97208.1 - 5 7.4 7.5 9.1 6.5 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) DUF92 PF01940.16 KKF97209.1 - 5.1e-66 222.5 0.4 6.3e-66 222.2 0.4 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 UCR_Fe-S_N PF10399.9 KKF97209.1 - 1.6 8.1 7.1 1.9 7.9 0.9 2.6 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Flavoprotein PF02441.19 KKF97210.1 - 1.9e-40 138.2 0.0 2.5e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Peptidase_C14 PF00656.22 KKF97211.1 - 1.1e-62 212.2 0.0 1.6e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain gag_pre-integrs PF13976.6 KKF97213.1 - 5.9e-07 29.3 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4134 PF13572.6 KKF97214.1 - 0.029 14.6 0.0 7 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) Mito_carr PF00153.27 KKF97215.1 - 7.8e-55 182.8 0.2 6.2e-22 77.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KKF97215.1 - 0.012 14.8 0.1 0.031 13.5 0.0 1.6 2 0 0 2 2 2 0 Gammaproteobacterial serine protease UDG PF03167.19 KKF97216.1 - 6e-22 78.3 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily SAPS PF04499.15 KKF97216.1 - 0.047 12.5 0.1 0.059 12.2 0.1 1.3 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein OCC1 PF15506.6 KKF97216.1 - 0.61 10.2 3.6 1.5 9.0 3.6 1.7 1 0 0 1 1 1 0 OCC1 family UDPGP PF01704.18 KKF97217.1 - 6.8e-56 189.7 0.0 8.7e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF1708 PF08101.11 KKF97218.1 - 4.1e-164 546.8 0.0 5.7e-164 546.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF726 PF05277.12 KKF97219.1 - 2.7e-07 29.9 0.9 4.4e-07 29.1 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) HSP70 PF00012.20 KKF97220.1 - 1.5e-226 753.3 9.0 1.7e-226 753.1 9.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKF97220.1 - 8.7e-18 64.2 0.6 8e-17 61.0 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KKF97220.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KKF97220.1 - 0.0014 18.1 0.1 0.49 9.8 0.0 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KKF97220.1 - 0.01 16.3 3.8 6.9 7.1 0.0 3.7 3 1 0 3 3 3 0 Cell division protein FtsA TOBE_3 PF12857.7 KKF97220.1 - 0.17 11.8 0.0 0.67 9.9 0.0 2.0 2 0 0 2 2 2 0 TOBE-like domain TraY PF05509.11 KKF97220.1 - 0.31 11.1 2.4 8.6 6.5 0.0 2.9 3 0 0 3 3 3 0 TraY domain RNA_pol_Rpb1_1 PF04997.12 KKF97222.1 - 1.3e-104 349.9 0.0 2.2e-104 349.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KKF97222.1 - 2.6e-100 335.3 0.0 4.4e-100 334.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KKF97222.1 - 6.8e-77 257.4 0.0 1.5e-76 256.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KKF97222.1 - 4.2e-56 189.8 0.3 7e-56 189.1 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KKF97222.1 - 4e-46 156.3 2.3 4e-46 156.3 2.3 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KKF97222.1 - 1.5e-43 148.5 0.0 4.5e-43 146.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KKF97222.1 - 1.6e-37 127.7 0.2 3.8e-37 126.5 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RRM_occluded PF16842.5 KKF97222.1 - 0.066 13.1 0.0 10 6.0 0.1 3.4 3 0 0 3 3 3 0 Occluded RNA-recognition motif WD40 PF00400.32 KKF97223.1 - 3.6e-14 52.9 3.7 0.0015 19.3 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF97223.1 - 1.4e-09 38.1 0.5 0.18 12.1 0.0 4.7 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKF97223.1 - 0.00011 22.1 0.1 0.098 12.5 0.0 3.2 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KKF97223.1 - 0.023 13.2 0.2 2.3 6.6 0.0 2.8 1 1 2 3 3 3 0 Cytochrome D1 heme domain Thg1C PF14413.6 KKF97224.1 - 4.1e-27 94.8 0.2 4.7e-27 94.6 0.2 1.0 1 0 0 1 1 1 1 Thg1 C terminal domain G-patch PF01585.23 KKF97225.1 - 0.0004 20.2 0.0 0.00093 19.0 0.0 1.6 1 1 0 1 1 1 1 G-patch domain LMBR1 PF04791.16 KKF97227.1 - 0.0013 17.8 0.1 0.0013 17.8 0.1 2.8 2 1 0 2 2 2 1 LMBR1-like membrane protein CPSF_A PF03178.15 KKF97228.1 - 6.4e-72 242.6 0.0 1.2e-71 241.7 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 KKF97228.1 - 1.8e-15 56.6 0.0 1.7e-14 53.3 0.0 2.4 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term HVSL PF09749.9 KKF97229.1 - 2.7e-50 171.1 0.0 1.9e-27 96.3 0.3 2.9 1 1 1 2 2 2 2 Uncharacterised conserved protein DUF1365 PF07103.11 KKF97229.1 - 0.0011 18.7 0.0 0.0014 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Serglycin PF04360.12 KKF97229.1 - 0.19 11.6 0.9 0.34 10.9 0.9 1.4 1 0 0 1 1 1 0 Serglycin ERO1 PF04137.15 KKF97230.1 - 1.9e-130 435.2 0.0 3.1e-130 434.5 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) GRIN_C PF15235.6 KKF97230.1 - 0.097 12.9 0.6 0.24 11.6 0.6 1.6 1 0 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus CKS PF01111.19 KKF97231.1 - 6.9e-31 106.3 0.6 1.1e-30 105.7 0.6 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.25 KKF97232.1 - 8.9e-30 102.6 3.8 8.2e-16 57.8 0.1 2.5 2 0 0 2 2 2 2 Bromodomain Mpp10 PF04006.12 KKF97232.1 - 0.12 10.8 30.5 0.14 10.6 14.6 2.2 2 0 0 2 2 2 0 Mpp10 protein Nop14 PF04147.12 KKF97232.1 - 0.17 10.1 37.3 0.24 9.5 17.7 2.3 2 0 0 2 2 2 0 Nop14-like family Raffinose_syn PF05691.12 KKF97233.1 - 1.1e-56 192.0 6.4 5.7e-52 176.5 3.4 3.7 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 ocr PF08684.10 KKF97233.1 - 0.064 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 DNA mimic ocr Peptidase_M16 PF00675.20 KKF97234.1 - 4.9e-55 185.6 0.6 1.2e-54 184.3 0.6 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KKF97234.1 - 3.8e-38 131.3 0.0 7.8e-37 127.1 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Histidinol_dh PF00815.20 KKF97235.1 - 3.6e-157 523.6 1.5 3.6e-157 523.6 1.5 1.5 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.18 KKF97235.1 - 2.7e-22 78.4 0.0 6e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KKF97235.1 - 1.7e-14 54.0 0.4 4.9e-14 52.5 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.15 KKF97236.1 - 3.1e-40 137.1 0.0 4.1e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit LRR_6 PF13516.6 KKF97237.1 - 0.00078 19.3 2.7 12 6.2 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 KKF97237.1 - 1.5 9.3 4.5 4.6 7.8 0.6 3.5 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) Ribosomal_S9 PF00380.19 KKF97238.1 - 5.7e-34 117.2 0.1 6.5e-34 117.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Uricase PF01014.18 KKF97239.1 - 2.3e-78 260.8 0.3 1.9e-39 134.9 0.1 2.0 2 0 0 2 2 2 2 Uricase IcmF_C PF06744.12 KKF97239.1 - 0.039 13.6 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal Ribosomal_L13 PF00572.18 KKF97240.1 - 3.7e-42 143.5 0.0 5.6e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 HMA PF00403.26 KKF97241.1 - 1.8e-10 41.1 0.0 3.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain TPR_2 PF07719.17 KKF97242.1 - 4.1e-16 57.7 1.9 3.7e-05 23.5 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKF97242.1 - 2.3e-15 55.7 4.0 2.6e-06 27.0 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKF97242.1 - 3e-10 39.5 0.5 4.2e-05 23.4 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKF97242.1 - 4e-10 39.8 0.5 3.3e-06 27.3 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKF97242.1 - 2.5e-09 37.1 0.1 0.23 12.2 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKF97242.1 - 1.1e-06 28.3 0.4 0.00041 20.2 0.0 3.8 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKF97242.1 - 5.8e-06 26.9 0.1 0.0032 18.1 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKF97242.1 - 7.8e-06 25.5 1.7 0.00041 20.0 0.3 3.8 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 KKF97242.1 - 0.00046 20.3 0.1 0.31 11.2 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKF97242.1 - 0.0015 18.8 0.1 2.4 8.7 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKF97242.1 - 0.0086 15.9 1.1 0.31 11.0 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PB1 PF00564.24 KKF97242.1 - 0.0087 16.0 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 PB1 domain TPR_14 PF13428.6 KKF97242.1 - 0.016 16.0 0.1 2.6 9.1 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KKF97242.1 - 0.031 14.4 0.2 0.093 12.8 0.1 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 KKF97242.1 - 0.039 14.6 0.0 37 5.3 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_1c PF00749.21 KKF97243.1 - 9.1e-23 80.6 0.0 1.4e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain WGG PF10273.9 KKF97243.1 - 0.041 14.5 1.2 1 10.1 0.1 2.4 2 1 0 2 2 2 0 Pre-rRNA-processing protein TSR2 DEDD_Tnp_IS110 PF01548.17 KKF97243.1 - 0.055 13.3 0.1 0.41 10.5 0.0 2.1 1 1 1 2 2 2 0 Transposase Ribosomal_L32e PF01655.18 KKF97244.1 - 4.1e-46 155.8 2.9 5e-46 155.6 1.4 1.9 1 1 1 2 2 2 1 Ribosomal protein L32 DnaJ_C PF01556.18 KKF97244.1 - 1e-32 113.3 0.1 2e-32 112.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKF97244.1 - 2.1e-24 85.4 2.3 5.1e-24 84.2 2.3 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKF97244.1 - 7.6e-13 48.6 17.1 1.5e-12 47.7 17.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Malate_DH PF12434.8 KKF97244.1 - 0.037 14.1 0.1 0.082 12.9 0.1 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Anti-TRAP PF15777.5 KKF97244.1 - 0.046 13.7 13.2 0.36 10.8 0.8 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KKF97244.1 - 0.71 9.9 6.3 4.6 7.3 0.9 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KKF97244.1 - 2.7 8.2 7.7 1.7 8.8 1.1 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 Lar_restr_allev PF14354.6 KKF97244.1 - 8.8 6.8 8.5 5.7 7.4 5.6 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar Alk_phosphatase PF00245.20 KKF97245.1 - 9.2e-104 347.7 0.0 1.1e-103 347.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KKF97245.1 - 0.015 14.7 0.0 0.044 13.1 0.0 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF624 PF04854.14 KKF97245.1 - 0.2 11.8 0.4 0.66 10.1 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF624 DUF498 PF04430.14 KKF97246.1 - 2.5e-22 79.0 0.0 3e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Ribosomal_L34e PF01199.18 KKF97247.1 - 1.1e-41 141.0 1.8 1.4e-41 140.7 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e PDGF PF00341.17 KKF97247.1 - 0.32 11.3 0.1 0.32 11.3 0.1 1.7 2 0 0 2 2 2 0 PDGF/VEGF domain FAR1 PF03101.15 KKF97248.1 - 6.2e-06 26.8 0.1 1.1e-05 26.0 0.1 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain XhlA PF10779.9 KKF97248.1 - 0.0058 16.8 0.0 0.017 15.3 0.0 1.8 1 1 0 1 1 1 1 Haemolysin XhlA Baculo_PEP_C PF04513.12 KKF97248.1 - 0.013 15.6 1.4 0.014 15.4 0.0 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KRE1 PF17056.5 KKF97248.1 - 0.019 14.7 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 AFT PF08731.11 KKF97248.1 - 0.03 14.7 0.6 0.049 14.0 0.6 1.6 1 1 0 1 1 1 0 Transcription factor AFT CLZ PF16526.5 KKF97248.1 - 0.037 14.4 1.6 0.82 10.1 0.3 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BioT2 PF15368.6 KKF97248.1 - 0.063 13.2 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Spermatogenesis family BioT2 DUF3086 PF11285.8 KKF97248.1 - 0.22 10.6 2.7 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) HSBP1 PF06825.12 KKF97248.1 - 0.45 10.4 6.9 1 9.2 0.8 2.5 1 1 1 2 2 2 0 Heat shock factor binding protein 1 HrpB7 PF09486.10 KKF97248.1 - 0.51 10.7 4.2 0.97 9.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Sugarporin_N PF11471.8 KKF97248.1 - 7.2 6.6 9.0 17 5.5 0.2 3.3 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension PBP_N PF17093.5 KKF97248.1 - 8.2 6.7 8.4 17 5.6 8.1 1.7 1 1 0 1 1 1 0 Penicillin-binding protein N-terminus DUF4678 PF15727.5 KKF97248.1 - 8.3 5.6 11.6 37 3.4 10.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4678) Polysacc_deac_1 PF01522.21 KKF97249.1 - 9.2e-29 99.9 0.0 1.4e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KKF97249.1 - 0.045 12.9 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 RrnaAD PF00398.20 KKF97250.1 - 1.8e-53 181.3 0.0 2.5e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KKF97250.1 - 3.9e-06 27.5 0.0 9.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KKF97250.1 - 6.6e-05 22.6 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_11 PF08241.12 KKF97250.1 - 0.00045 20.8 0.0 0.001 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKF97250.1 - 0.00052 19.6 0.0 0.00078 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KKF97250.1 - 0.0016 17.7 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KKF97250.1 - 0.0045 17.7 0.0 0.0098 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KKF97250.1 - 0.0054 16.5 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KKF97250.1 - 0.008 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF97250.1 - 0.0099 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKF97250.1 - 0.042 13.2 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AAA_lid_4 PF17864.1 KKF97250.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 RuvB AAA lid domain UPF0020 PF01170.18 KKF97250.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF4611 PF15387.6 KKF97250.1 - 7.4 6.9 8.3 23 5.3 8.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PRP1_N PF06424.12 KKF97251.1 - 1.5e-51 174.7 10.5 4.2e-51 173.3 10.5 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 KKF97251.1 - 4.5e-30 104.0 6.0 2.7e-08 34.2 0.9 9.3 6 3 2 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 KKF97251.1 - 1.9e-28 96.7 24.6 0.0011 19.6 0.3 13.4 5 3 7 13 13 12 9 Tetratricopeptide repeat TPR_16 PF13432.6 KKF97251.1 - 1e-12 48.5 7.6 0.00092 19.8 0.3 8.1 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKF97251.1 - 2.2e-12 46.1 5.6 3.5 8.0 0.0 10.8 13 1 0 13 13 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKF97251.1 - 4.3e-09 35.9 2.7 0.92 9.9 0.0 7.1 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KKF97251.1 - 1.3e-08 34.9 0.8 0.051 13.7 0.0 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKF97251.1 - 3e-08 33.5 1.8 0.17 12.3 0.0 7.7 8 1 1 9 9 7 1 Tetratricopeptide repeat NARP1 PF12569.8 KKF97251.1 - 1.3e-07 30.9 10.8 0.18 10.7 0.0 6.0 5 1 2 7 7 7 3 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 KKF97251.1 - 1.5e-05 24.6 0.1 0.1 12.4 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKF97251.1 - 7.8e-05 22.3 0.3 0.87 9.3 0.1 5.8 6 0 0 6 6 6 1 TPR repeat TPR_21 PF09976.9 KKF97251.1 - 0.0002 21.2 15.6 0.059 13.1 2.4 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 KKF97251.1 - 0.00021 21.3 0.9 7.8 6.4 0.0 5.0 3 2 2 5 5 5 1 Virulence factor membrane-bound polymerase, C-terminal DUF3808 PF10300.9 KKF97251.1 - 0.00024 20.0 3.0 0.99 8.1 0.0 4.4 4 1 0 5 5 5 2 Protein of unknown function (DUF3808) TPR_6 PF13174.6 KKF97251.1 - 0.001 19.6 7.6 79 4.2 0.0 7.8 7 1 0 7 7 5 0 Tetratricopeptide repeat Suf PF05843.14 KKF97251.1 - 0.0015 18.5 2.3 2.3 8.1 0.0 4.4 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) ZNRF_3_ecto PF18212.1 KKF97251.1 - 0.0039 17.2 0.6 10 6.1 0.0 3.9 3 0 0 3 3 3 0 ZNRF-3 Ectodomain NTP_transf_7 PF07984.12 KKF97251.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase Dynamitin PF04912.14 KKF97252.1 - 0.0039 16.6 1.2 0.0067 15.8 1.2 1.2 1 0 0 1 1 1 1 Dynamitin Trimer_CC PF08954.11 KKF97252.1 - 0.056 13.0 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Trimerisation motif Vps62 PF06101.11 KKF97253.1 - 5.9e-11 41.4 0.4 1.3e-10 40.3 0.4 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 DUF1302 PF06980.11 KKF97253.1 - 0.031 12.9 0.1 0.046 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Hexapep PF00132.24 KKF97254.1 - 8.6e-09 34.8 10.2 7.5e-05 22.3 5.5 4.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKF97254.1 - 1.1e-05 25.1 0.9 0.17 11.7 0.4 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KKF97254.1 - 0.024 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase AIM24 PF01987.17 KKF97255.1 - 1.4e-53 181.7 0.2 2e-53 181.2 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 TRP PF06011.12 KKF97256.1 - 1.8e-156 521.2 28.8 2.2e-156 520.9 28.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KKF97256.1 - 1.2e-38 132.6 0.0 2.1e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 ML-like domain TcpE PF12648.7 KKF97256.1 - 3.5 8.2 14.1 1.2 9.7 1.8 3.4 2 1 0 2 2 2 0 TcpE family DUF3433 PF11915.8 KKF97257.1 - 3.4e-44 149.2 13.1 9e-24 83.8 1.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Transglut_core PF01841.19 KKF97258.1 - 3.7e-13 49.9 0.1 6.3e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily Glycos_transf_4 PF00953.21 KKF97258.1 - 3.4e-05 23.9 1.6 3.4e-05 23.9 1.6 2.6 4 0 0 4 4 4 1 Glycosyl transferase family 4 Gln_amidase PF15644.6 KKF97258.1 - 0.032 15.3 0.1 0.058 14.4 0.1 1.5 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase DUF553 PF04473.12 KKF97258.1 - 0.076 12.5 0.0 2.5 7.6 0.1 2.7 2 1 0 2 2 2 0 Transglutaminase-like domain PHD PF00628.29 KKF97259.1 - 6.6e-08 32.3 10.4 1.2e-07 31.5 10.4 1.4 1 0 0 1 1 1 1 PHD-finger LCE PF14672.6 KKF97259.1 - 0.11 13.2 5.1 0.25 11.9 5.1 1.6 1 0 0 1 1 1 0 Late cornified envelope MMR_HSR1 PF01926.23 KKF97260.1 - 9.1e-05 22.5 0.0 0.69 10.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Replicase PF03090.17 KKF97260.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Replicase family L51_S25_CI-B8 PF05047.16 KKF97261.1 - 1e-14 54.2 0.0 1.9e-14 53.3 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HECT PF00632.25 KKF97262.1 - 2.1e-72 244.2 0.0 2.9e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ADH_N PF08240.12 KKF97263.1 - 7.8e-25 86.9 0.2 1.7e-24 85.8 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKF97263.1 - 4.2e-16 59.1 0.0 6.5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKF97263.1 - 3.1e-10 39.9 0.0 4.6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKF97263.1 - 7.4e-09 36.8 0.0 1.5e-08 35.7 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KKF97263.1 - 0.0037 16.6 0.2 0.006 15.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KKF97263.1 - 0.0057 17.1 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Staph_opine_DH PF10100.9 KKF97263.1 - 0.016 13.8 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase Sacchrp_dh_NADP PF03435.18 KKF97263.1 - 0.03 14.6 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 KKF97263.1 - 0.11 13.0 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_3 PF03447.16 KKF97263.1 - 0.14 12.8 0.0 0.23 12.1 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain S10_plectin PF03501.15 KKF97264.1 - 2.2e-40 136.6 0.1 2.8e-40 136.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Sde2_N_Ubi PF13019.6 KKF97265.1 - 3.9e-58 195.9 0.1 6.2e-58 195.3 0.1 1.3 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Macoilin PF09726.9 KKF97265.1 - 0.83 8.1 6.4 1.1 7.8 6.4 1.1 1 0 0 1 1 1 0 Macoilin family COX6B PF02297.17 KKF97266.1 - 7.5e-20 71.0 4.3 8.7e-20 70.7 4.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KKF97266.1 - 0.018 15.0 3.0 0.022 14.8 2.1 1.5 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ketoacyl-synt PF00109.26 KKF97266.1 - 0.044 13.3 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain CHCH PF06747.13 KKF97266.1 - 0.079 13.1 0.8 0.21 11.8 0.8 1.8 1 1 0 1 1 1 0 CHCH domain APOBEC_C PF05240.14 KKF97266.1 - 0.082 12.9 2.2 0.076 13.0 1.2 1.6 1 1 0 1 1 1 0 APOBEC-like C-terminal domain B12D PF06522.11 KKF97267.1 - 1.8e-05 24.4 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.22 KKF97268.1 - 8.9e-16 57.5 0.1 2.8e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKF97268.1 - 1.6e-05 24.9 0.0 2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 KKF97268.1 - 0.0073 16.3 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KKF97268.1 - 0.014 15.2 0.0 0.055 13.3 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KKF97268.1 - 0.047 13.7 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KKF97268.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Sec16_C PF12931.7 KKF97269.1 - 1.6e-14 54.3 0.8 9e-14 51.8 0.8 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 KKF97269.1 - 1e-07 31.9 0.0 1e-07 31.9 0.0 3.8 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 KKF97269.1 - 2.5e-05 25.0 6.5 0.25 12.3 0.0 6.1 6 0 0 6 6 6 1 WD domain, G-beta repeat Sec16 PF12932.7 KKF97269.1 - 0.017 15.7 0.0 0.051 14.2 0.0 1.8 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Prp18 PF02840.15 KKF97269.1 - 0.14 12.2 0.2 1.2 9.2 0.0 2.2 1 1 1 2 2 2 0 Prp18 domain GET2 PF08690.10 KKF97270.1 - 5.1e-20 72.4 0.6 2.6e-11 43.8 0.0 2.1 1 1 1 2 2 2 2 GET complex subunit GET2 HMGL-like PF00682.19 KKF97271.1 - 6.3e-79 265.2 0.3 9.3e-79 264.7 0.3 1.2 1 0 0 1 1 1 1 HMGL-like adh_short PF00106.25 KKF97272.1 - 1.4e-20 73.6 0.1 1.3e-16 60.6 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKF97272.1 - 1.6e-11 44.2 0.2 8e-10 38.7 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKF97272.1 - 1e-07 32.1 0.2 1.5e-07 31.5 0.2 1.3 1 0 0 1 1 1 1 KR domain HLH PF00010.26 KKF97273.1 - 4.8e-06 26.4 0.0 9.8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Gp_dh_C PF02800.20 KKF97274.1 - 1.2e-71 239.4 0.1 2.3e-71 238.5 0.0 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KKF97274.1 - 2.6e-37 127.2 0.2 6e-37 126.0 0.2 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KKF97274.1 - 0.063 13.4 0.1 0.23 11.6 0.0 2.0 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 KKF97274.1 - 0.086 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Trypan_PARP PF05887.11 KKF97275.1 - 0.0049 16.8 9.6 0.0049 16.8 9.6 2.3 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) PRP38_assoc PF12871.7 KKF97275.1 - 0.0064 17.1 30.4 0.0064 17.1 30.4 2.4 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term UBN_AB PF14075.6 KKF97276.1 - 0.013 15.2 3.4 0.036 13.8 0.3 2.1 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Tht1 PF04163.12 KKF97276.1 - 0.063 12.0 0.6 0.32 9.7 0.1 1.9 2 0 0 2 2 2 0 Tht1-like nuclear fusion protein DUF4795 PF16043.5 KKF97276.1 - 0.095 12.3 1.5 0.12 12.0 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF2666 PF10869.8 KKF97276.1 - 0.12 12.6 0.0 3 8.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) TBCA PF02970.16 KKF97276.1 - 0.29 11.5 0.0 0.29 11.5 0.0 2.4 4 1 0 4 4 4 0 Tubulin binding cofactor A GYF PF02213.16 KKF97277.1 - 2.1e-12 46.5 2.8 4.4e-12 45.5 2.8 1.6 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.13 KKF97278.1 - 5.1e-152 506.1 1.7 6.3e-152 505.8 1.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KKF97278.1 - 9.7e-22 76.9 0.2 5.2e-21 74.5 0.1 2.4 3 0 0 3 3 3 1 TIP49 AAA-lid domain AAA PF00004.29 KKF97278.1 - 1.4e-08 35.2 0.7 1.7e-05 25.3 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKF97278.1 - 4.2e-08 33.1 0.4 2.7e-05 24.0 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KKF97278.1 - 5.2e-07 29.3 0.8 8.9e-07 28.5 0.8 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KKF97278.1 - 4e-05 24.1 0.1 0.00012 22.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KKF97278.1 - 0.011 16.1 0.7 0.28 11.5 0.7 2.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKF97278.1 - 0.012 15.2 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKF97278.1 - 0.012 15.8 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KKF97278.1 - 0.024 14.0 0.8 0.21 11.0 0.3 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KKF97278.1 - 0.029 14.6 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KKF97278.1 - 0.05 13.4 0.4 0.16 11.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KKF97278.1 - 0.067 13.7 0.0 0.27 11.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain UFD1 PF03152.14 KKF97279.1 - 1.1e-67 226.8 0.0 1.4e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 SMYLE_N PF18615.1 KKF97280.1 - 0.086 12.4 8.6 0.099 12.2 8.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Myb_DNA-bind_3 PF12776.7 KKF97280.1 - 0.97 10.5 7.1 0.95 10.5 2.2 2.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain ALMT PF11744.8 KKF97280.1 - 1.1 8.0 11.7 1.4 7.7 11.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 KKF97280.1 - 1.9 6.7 29.1 2.1 6.5 29.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 KKF97280.1 - 2 8.1 13.9 3.1 7.6 13.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Activator_LAG-3 PF11498.8 KKF97280.1 - 2.4 7.0 47.5 3.6 6.5 47.5 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CDK5_activator PF03261.15 KKF97280.1 - 2.7 7.4 12.6 3.7 7.0 12.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein GREB1 PF15782.5 KKF97280.1 - 2.8 5.0 17.7 3.2 4.8 17.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RNase_E_G PF10150.9 KKF97280.1 - 5 6.4 8.8 7.9 5.8 8.8 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family GET2 PF08690.10 KKF97280.1 - 5.6 6.6 19.3 7.2 6.2 19.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Cpn60_TCP1 PF00118.24 KKF97281.1 - 6.2e-86 289.0 11.2 1.2e-85 288.0 11.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.20 KKF97282.1 - 6.3e-38 129.3 0.3 6.9e-38 129.2 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AAA_14 PF13173.6 KKF97282.1 - 0.099 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain Blt1 PF12754.7 KKF97283.1 - 3.8e-34 118.2 0.1 5.1e-34 117.7 0.1 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KKF97283.1 - 4.4e-12 45.4 0.9 8.4e-12 44.5 0.9 1.5 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 KKF97283.1 - 0.00015 21.5 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 KKF97283.1 - 0.058 13.8 0.1 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain Methyltr_RsmB-F PF01189.17 KKF97284.1 - 8.6e-77 257.3 0.2 1.9e-76 256.2 0.0 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KKF97284.1 - 1.5e-07 31.8 0.9 4.6e-07 30.2 0.0 2.4 3 0 0 3 3 3 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_25 PF13649.6 KKF97284.1 - 0.0016 19.1 0.0 0.0049 17.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KKF97284.1 - 0.007 16.5 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KKF97284.1 - 0.0075 16.1 0.0 0.023 14.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DUF2431 PF10354.9 KKF97284.1 - 0.027 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) XRCC4 PF06632.12 KKF97286.1 - 1.3e-07 30.8 1.8 1.7e-07 30.4 1.8 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 FlxA PF14282.6 KKF97286.1 - 0.46 10.5 9.2 2 8.5 9.2 1.9 1 1 0 1 1 1 0 FlxA-like protein Aldo_ket_red PF00248.21 KKF97287.1 - 8.9e-30 103.9 0.0 1.2e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.14 KKF97288.1 - 1.2e-129 433.2 0.0 1.5e-129 432.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Cytochrom_C552 PF02335.15 KKF97288.1 - 0.11 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c552 Molybdopterin PF00384.22 KKF97289.1 - 6.8e-75 252.7 0.0 1e-72 245.5 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 KKF97289.1 - 9.4e-19 67.8 0.0 2.4e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KKF97289.1 - 4.7e-17 61.2 0.2 4.7e-17 61.2 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region TPP_enzyme_M PF00205.22 KKF97289.1 - 0.0073 16.0 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer2_4 PF13510.6 KKF97289.1 - 0.052 13.6 0.1 0.39 10.8 0.0 2.4 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 KKF97289.1 - 0.13 12.1 1.1 3.3 7.7 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KKF97289.1 - 0.4 10.8 2.4 0.5 10.5 1.0 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain ACBP PF00887.19 KKF97290.1 - 4.1e-22 78.2 0.0 9.3e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Ribonuclease_3 PF00636.26 KKF97291.1 - 1.6e-16 60.9 0.0 6.3e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKF97291.1 - 4.8e-15 55.9 0.0 1.3e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 KKF97291.1 - 0.0074 17.0 0.0 0.022 15.5 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif MRP-S33 PF08293.11 KKF97292.1 - 1.5e-27 95.6 0.0 1.9e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.19 KKF97293.1 - 3.5e-37 124.0 0.4 1.1e-06 28.0 0.0 7.9 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat RasGEF PF00617.19 KKF97293.1 - 0.025 14.8 0.2 0.074 13.3 0.1 1.8 2 0 0 2 2 2 0 RasGEF domain RraB PF06877.11 KKF97293.1 - 0.028 15.1 0.0 0.065 14.0 0.0 1.6 1 0 0 1 1 1 0 Regulator of ribonuclease activity B PP2C PF00481.21 KKF97294.1 - 8.2e-43 146.9 0.0 1.3e-42 146.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KKF97294.1 - 0.0083 16.1 0.0 0.54 10.1 0.0 2.8 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) ApoC-I PF04691.12 KKF97294.1 - 0.12 12.4 0.8 4 7.4 0.1 2.3 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) OAD_gamma PF04277.13 KKF97295.1 - 0.012 16.1 0.9 0.022 15.4 0.5 1.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain SHR3_chaperone PF08229.11 KKF97295.1 - 0.018 14.1 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 PAP_PilO PF06864.12 KKF97295.1 - 0.026 13.4 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Nckap1 PF09735.9 KKF97295.1 - 0.066 11.2 0.0 0.074 11.0 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Ceramidase PF05875.12 KKF97295.1 - 0.12 11.8 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Ceramidase Ribosomal_S5_C PF03719.15 KKF97296.1 - 2e-22 78.4 0.2 7.3e-22 76.6 0.0 2.2 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KKF97296.1 - 1.8e-17 63.0 2.3 3.4e-17 62.2 2.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Sigma70_r3 PF04539.16 KKF97296.1 - 0.0013 18.8 0.1 0.23 11.6 0.1 2.6 2 0 0 2 2 2 1 Sigma-70 region 3 MTS PF05175.14 KKF97296.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DASH_Dad3 PF08656.10 KKF97297.1 - 3.8e-19 68.5 0.3 5.3e-19 68.1 0.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 DUF5356 PF17309.2 KKF97297.1 - 0.018 15.1 0.2 0.021 14.8 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5356) PSP1 PF04468.12 KKF97298.1 - 2e-12 47.2 0.4 4.3e-12 46.1 0.4 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF5094 PF17015.5 KKF97298.1 - 0.21 11.7 0.1 0.21 11.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) Tad PF13400.6 KKF97298.1 - 0.53 10.6 3.7 1.1 9.7 3.7 1.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Ribosomal_L15e PF00827.17 KKF97299.1 - 2e-90 301.6 10.8 2.5e-90 301.3 10.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 PUF PF00806.19 KKF97300.1 - 2.5e-55 181.2 12.1 3.6e-09 35.8 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat GAS PF13851.6 KKF97300.1 - 0.96 8.8 7.3 1.9 7.8 7.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding RNA_pol_Rpb2_6 PF00562.28 KKF97301.1 - 1.8e-119 399.3 0.0 2.9e-119 398.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKF97301.1 - 2.2e-54 184.0 0.6 3.3e-54 183.5 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KKF97301.1 - 7.8e-33 112.7 0.4 1.9e-32 111.5 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KKF97301.1 - 5.5e-29 101.1 0.0 1.3e-28 99.9 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KKF97301.1 - 5.3e-22 77.9 0.0 1.3e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KKF97301.1 - 3.2e-19 68.9 0.0 6.6e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KKF97301.1 - 2.2e-11 44.2 0.7 6.5e-11 42.6 0.7 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MMU163 PF17119.5 KKF97302.1 - 7e-75 251.4 2.5 4.7e-56 189.7 0.4 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Tom5 PF10642.9 KKF97302.1 - 0.14 12.2 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Pkinase PF00069.25 KKF97303.1 - 1.3e-64 218.2 0.0 2.9e-64 217.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF97303.1 - 5.1e-24 85.0 0.0 9.8e-24 84.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF97303.1 - 0.00027 20.3 0.1 0.4 9.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like DGF-1_C PF11040.8 KKF97304.1 - 0.1 12.6 0.8 0.6 10.2 0.3 2.2 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DFRP_C PF16543.5 KKF97305.1 - 3.8e-25 88.2 5.6 3.8e-25 88.2 5.6 3.5 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 KKF97305.1 - 2e-06 28.5 0.7 2e-06 28.5 0.7 3.7 2 2 2 4 4 4 1 Torus domain zf-CCCH PF00642.24 KKF97305.1 - 2.8e-06 27.1 1.2 2.8e-06 27.1 1.2 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KKF97305.1 - 0.00013 21.9 6.7 0.00013 21.9 6.7 2.7 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 KKF97305.1 - 0.00035 20.3 7.0 0.00045 19.9 2.1 2.9 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KKF97305.1 - 0.0083 16.3 0.1 0.32 11.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KKF97305.1 - 0.03 14.8 11.4 0.068 13.7 5.2 2.7 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RRM_1 PF00076.22 KKF97306.1 - 2.4e-17 62.5 0.0 4.4e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKF97306.1 - 0.0045 16.8 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif FoP_duplication PF13865.6 KKF97306.1 - 0.01 16.3 4.8 0.01 16.3 4.8 2.9 2 2 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_60s PF00428.19 KKF97306.1 - 0.31 11.7 22.0 2.4 8.8 1.6 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF5102 PF17104.5 KKF97306.1 - 3.1 7.8 10.8 0.98 9.4 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) CS PF04969.16 KKF97307.1 - 1.5e-08 35.5 0.2 2.5e-08 34.8 0.2 1.3 1 0 0 1 1 1 1 CS domain Snf7 PF03357.21 KKF97308.1 - 1.4e-15 57.3 10.4 1.4e-15 57.3 10.4 2.0 1 1 1 2 2 2 1 Snf7 Ureide_permease PF07168.11 KKF97308.1 - 0.074 11.8 1.1 0.11 11.3 1.1 1.2 1 0 0 1 1 1 0 Ureide permease DUF2408 PF10303.9 KKF97308.1 - 0.22 12.1 3.5 0.082 13.5 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3484 PF11983.8 KKF97308.1 - 4 8.6 5.9 0.48 11.6 0.6 2.1 2 1 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch WD40 PF00400.32 KKF97309.1 - 2.1e-27 94.8 4.3 6e-06 26.9 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF97309.1 - 0.00087 19.5 0.0 0.074 13.4 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKF97309.1 - 0.0021 16.8 0.0 5.5 5.5 0.1 3.8 2 1 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KKF97309.1 - 0.0042 16.5 0.0 0.017 14.5 0.0 2.1 2 1 0 2 2 2 1 WD40-like domain Proteasome PF00227.26 KKF97310.1 - 6e-29 100.9 0.0 6.8e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sigma54_AID PF00309.20 KKF97310.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) DEAD PF00270.29 KKF97311.1 - 3.1e-48 163.8 0.0 1.1e-47 162.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF97311.1 - 3e-32 111.3 0.0 8.6e-32 109.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKF97311.1 - 0.026 14.5 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 KKF97311.1 - 0.048 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit CDV3 PF15359.6 KKF97311.1 - 0.13 12.7 0.5 0.27 11.7 0.5 1.4 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 AMP-binding PF00501.28 KKF97312.1 - 8.3e-14 51.0 0.0 5.3e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Lysine_decarbox PF03641.14 KKF97313.1 - 1.6e-28 99.4 0.0 2.3e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KKF97313.1 - 4.1e-05 23.2 2.1 0.00021 20.9 2.0 1.9 1 1 0 1 1 1 1 SLOG cluster4 family DAGK_cat PF00781.24 KKF97313.1 - 0.092 12.4 1.5 8.2 6.1 0.3 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain AAA_lid_2 PF17863.1 KKF97313.1 - 0.092 12.6 0.3 0.72 9.7 0.1 2.4 3 0 0 3 3 3 0 AAA lid domain Proteasome PF00227.26 KKF97314.1 - 4.2e-49 166.6 0.0 5.4e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKF97314.1 - 7.6e-12 44.7 0.3 1.3e-11 44.0 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.14 KKF97315.1 - 3.7e-44 149.4 8.2 4.2e-44 149.2 8.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 ABC2_membrane_3 PF12698.7 KKF97315.1 - 3.5 6.6 9.8 4.6 6.3 9.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4349 PF14257.6 KKF97315.1 - 6 6.2 4.5 0.69 9.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Chorismate_bind PF00425.18 KKF97316.1 - 2.6e-51 174.7 0.1 2.9e-51 174.5 0.1 1.0 1 0 0 1 1 1 1 chorismate binding enzyme TRAPPC9-Trs120 PF08626.11 KKF97317.1 - 1.5e-233 777.9 0.0 1.8e-233 777.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit adh_short PF00106.25 KKF97318.1 - 2.7e-18 66.1 0.0 4.2e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKF97318.1 - 5.7e-16 58.8 0.0 8.1e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KKF97318.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3523 PF12037.8 KKF97319.1 - 0.04 13.3 0.3 0.04 13.3 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) Hap4_Hap_bind PF10297.9 KKF97320.1 - 3.4e-09 36.5 6.9 3.4e-09 36.5 6.9 2.1 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KKF97320.1 - 0.00048 20.2 9.0 0.00048 20.2 9.0 2.6 2 1 1 3 3 2 1 bZIP transcription factor Cmyb_C PF09316.10 KKF97320.1 - 0.0017 18.1 0.7 0.0035 17.0 0.7 1.6 1 0 0 1 1 1 1 C-myb, C-terminal Spt20 PF12090.8 KKF97320.1 - 0.0057 16.3 10.0 0.0096 15.6 10.0 1.4 1 0 0 1 1 1 1 Spt20 family dsrm PF00035.26 KKF97320.1 - 0.01 16.5 0.7 0.036 14.8 0.0 2.1 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF3371 PF11851.8 KKF97320.1 - 0.019 16.1 4.4 0.019 16.1 4.4 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3371) BolA PF01722.18 KKF97320.1 - 0.032 14.5 1.6 0.043 14.1 0.2 1.9 2 0 0 2 2 2 0 BolA-like protein FAM60A PF15396.6 KKF97320.1 - 0.12 12.4 5.2 0.18 11.8 5.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Fmp27_WPPW PF10359.9 KKF97320.1 - 0.35 9.7 13.3 0.44 9.4 13.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain SUIM_assoc PF16619.5 KKF97320.1 - 2.1 8.4 18.9 4.6 7.4 18.1 2.1 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RBM39linker PF15519.6 KKF97320.1 - 2.2 9.4 10.1 2.7 9.1 0.1 2.7 1 1 1 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein E_Pc_C PF06752.12 KKF97320.1 - 3.7 7.6 17.7 6.5 6.8 17.7 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus V_ATPase_I PF01496.19 KKF97320.1 - 4.5 5.1 11.5 5.8 4.7 11.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 KKF97320.1 - 5.6 7.0 5.6 8 6.4 5.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3646 PF12362.8 KKF97320.1 - 5.7 7.3 9.5 1.6 9.0 0.8 2.2 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal Exonuc_VII_L PF02601.15 KKF97320.1 - 7.7 6.0 13.1 9.7 5.7 13.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rrp15p PF07890.12 KKF97323.1 - 4.6e-37 127.4 11.9 4.6e-37 127.4 11.9 2.2 2 1 0 2 2 2 1 Rrp15p Fer2 PF00111.27 KKF97324.1 - 4.2e-14 52.2 0.5 5.6e-14 51.9 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.27 KKF97325.1 - 4.4e-18 65.0 1.5 9.7e-05 22.2 0.0 5.4 5 0 0 5 5 5 5 Mitochondrial carrier protein Thymidylate_kin PF02223.17 KKF97327.1 - 5.3e-32 111.0 0.0 3.6e-31 108.3 0.0 1.9 1 1 1 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 KKF97327.1 - 0.063 13.5 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_cyclohydroI PF01227.22 KKF97328.1 - 8.3e-71 237.1 1.9 8.3e-71 237.1 1.9 1.5 2 0 0 2 2 2 1 GTP cyclohydrolase I QueF PF14489.6 KKF97328.1 - 0.0024 18.0 0.0 0.0055 16.8 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein WW_FCH_linker PF16623.5 KKF97328.1 - 0.3 11.9 10.6 1.3 9.9 6.2 2.4 2 0 0 2 2 2 0 Unstructured linker region between on GAS7 protein DUF4820 PF16091.5 KKF97328.1 - 4.4 6.6 7.2 8.2 5.7 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Ribosomal_L27 PF01016.19 KKF97329.1 - 9.4e-21 73.6 0.0 9.4e-21 73.6 0.0 2.1 3 0 0 3 3 3 1 Ribosomal L27 protein ECR1_N PF14382.6 KKF97329.1 - 0.049 13.5 0.2 0.09 12.6 0.2 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region IPP-2 PF04979.14 KKF97330.1 - 3.2e-25 89.4 8.4 5.4e-25 88.7 8.4 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) ANAPC10 PF03256.16 KKF97331.1 - 1.2e-47 162.0 0.0 1.8e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Beta-Casp PF10996.8 KKF97331.1 - 0.096 13.0 0.0 0.24 11.7 0.0 1.8 1 1 0 1 1 1 0 Beta-Casp domain DUF2457 PF10446.9 KKF97331.1 - 1.4 8.0 13.7 2 7.5 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Band_7 PF01145.25 KKF97332.1 - 8.8e-28 97.5 2.6 1.5e-27 96.7 2.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KKF97332.1 - 0.034 13.9 0.2 0.055 13.2 0.2 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Kinesin_assoc PF16183.5 KKF97332.1 - 0.21 11.7 2.2 0.28 11.3 1.0 1.7 2 0 0 2 2 2 0 Kinesin-associated Nop PF01798.18 KKF97333.1 - 7.1e-75 251.4 0.9 1.6e-74 250.2 0.9 1.7 1 1 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KKF97333.1 - 1.3e-17 63.9 0.4 7.4e-17 61.5 0.4 2.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.16 KKF97334.1 - 2.8e-100 336.1 0.0 3.3e-100 335.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.22 KKF97335.1 - 2.8e-23 81.9 0.7 9.6e-23 80.2 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S2 PF00318.20 KKF97336.1 - 5.7e-26 91.1 0.1 2.2e-14 53.2 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KKF97336.1 - 0.32 12.4 19.5 2.7 9.4 19.5 2.2 1 1 0 1 1 1 0 40S ribosomal protein SA C-terminus VTC PF09359.10 KKF97337.1 - 1.3e-85 287.2 0.1 2.5e-85 286.2 0.1 1.5 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KKF97337.1 - 1.3e-13 51.2 1.8 1.3e-13 51.2 1.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KKF97337.1 - 5.3e-09 36.5 0.9 6.3e-06 26.3 0.0 3.8 3 1 1 4 4 4 2 SPX domain NnrS PF05940.12 KKF97337.1 - 0.037 13.4 1.0 0.053 12.9 1.0 1.1 1 0 0 1 1 1 0 NnrS protein SLBP_RNA_bind PF15247.6 KKF97337.1 - 0.063 13.4 0.4 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Nic96 PF04097.14 KKF97338.1 - 3.1e-205 683.3 0.0 4.2e-205 682.9 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 FGGY_C PF02782.16 KKF97338.1 - 4.4e-48 163.6 0.4 9.4e-48 162.6 0.4 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKF97338.1 - 1.8e-11 44.1 0.0 1.6e-10 41.0 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Myb_DNA-binding PF00249.31 KKF97340.1 - 4e-06 26.9 0.0 0.19 11.9 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KKF97340.1 - 1.9e-05 24.5 14.7 2.9e-05 23.9 0.0 3.3 3 0 0 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KKF97340.1 - 0.023 15.0 0.2 2.9 8.2 0.1 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain MCM_bind PF09739.9 KKF97340.1 - 1.8 6.9 10.4 3.2 6.1 10.4 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Red1 PF07964.11 KKF97340.1 - 4.8 5.3 14.1 7.7 4.6 14.1 1.3 1 0 0 1 1 1 0 Rec10 / Red1 DUF4551 PF15087.6 KKF97340.1 - 4.9 5.9 19.9 0.16 10.8 13.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) DS PF01916.17 KKF97342.1 - 1.5e-109 365.7 0.0 2.3e-109 365.1 0.0 1.2 1 0 0 1 1 1 1 Deoxyhypusine synthase Pro_isomerase PF00160.21 KKF97342.1 - 2.4e-41 141.6 0.0 6e-41 140.4 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD IF2_assoc PF08364.11 KKF97342.1 - 1.7 8.9 5.6 6.8 7.0 5.6 2.0 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region HSF_DNA-bind PF00447.17 KKF97343.1 - 5.3e-27 94.3 0.4 5.3e-27 94.3 0.4 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Nsp1_C PF05064.13 KKF97343.1 - 0.026 14.3 0.8 0.069 13.0 0.8 1.7 1 0 0 1 1 1 0 Nsp1-like C-terminal region Pro_isomerase PF00160.21 KKF97344.1 - 2e-46 158.1 0.0 2.3e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_hydro_63 PF03200.16 KKF97345.1 - 6.2e-09 35.1 10.7 1.8e-06 27.0 0.1 4.0 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain OSCP PF00213.18 KKF97346.1 - 3.6e-45 154.2 4.1 4.7e-45 153.8 4.1 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Mob1_phocein PF03637.17 KKF97347.1 - 7.4e-42 143.2 0.1 8.9e-42 143.0 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family ATP-grasp_2 PF08442.10 KKF97348.1 - 1.2e-76 256.8 2.2 1.3e-76 256.7 0.5 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KKF97348.1 - 2.5e-26 92.3 0.4 5.1e-26 91.3 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KKF97348.1 - 6.8e-07 29.0 0.4 1.9e-06 27.5 0.1 1.9 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KKF97348.1 - 0.0025 17.6 0.7 0.044 13.6 0.1 2.4 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Arteri_nsp7a PF16749.5 KKF97348.1 - 0.073 13.3 0.3 0.39 10.9 0.1 2.1 2 0 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha OKR_DC_1_N PF03709.15 KKF97348.1 - 0.13 12.6 0.5 2.4 8.5 0.1 2.5 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Thr_synth_N PF14821.6 KKF97349.1 - 1.2e-28 99.1 0.0 2.6e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KKF97349.1 - 6.8e-20 71.7 0.0 5.6e-17 62.1 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme DUF1424 PF07232.11 KKF97349.1 - 0.016 14.2 0.1 2.4 7.1 0.0 2.6 2 1 1 3 3 3 0 Putative rep protein (DUF1424) RTP1_C2 PF10304.9 KKF97350.1 - 3.3e-14 52.2 0.1 5.7e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 RTP1_C1 PF10363.9 KKF97350.1 - 4.9e-10 39.6 0.0 1.2e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF5531 PF17671.1 KKF97351.1 - 0.18 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5531) MBOAT PF03062.19 KKF97352.1 - 2e-49 168.8 17.8 2e-49 168.8 17.8 1.8 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Phtf-FEM1B_bdg PF12129.8 KKF97352.1 - 0.16 11.8 2.5 0.47 10.3 2.5 1.8 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Glyco_hydro_76 PF03663.14 KKF97353.1 - 2.6e-22 79.8 1.5 6.1e-21 75.4 0.4 3.2 1 1 0 2 2 2 1 Glycosyl hydrolase family 76 Cep57_MT_bd PF06657.13 KKF97354.1 - 9.3e-31 106.1 0.1 9.3e-31 106.1 0.1 7.2 5 2 3 8 8 8 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KKF97354.1 - 9.6e-18 64.0 69.4 9.4e-10 38.4 2.5 6.6 4 1 2 6 6 6 3 Centrosome localisation domain of PPC89 NAGPA PF09992.9 KKF97354.1 - 0.0023 18.1 0.1 0.0058 16.8 0.1 1.6 1 0 0 1 1 1 1 Phosphodiester glycosidase KASH_CCD PF14662.6 KKF97354.1 - 0.0034 17.2 79.9 0.026 14.4 13.1 5.8 3 1 2 5 5 5 2 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 KKF97354.1 - 0.1 12.8 45.9 0.22 11.7 2.7 8.6 5 2 2 7 7 7 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 KKF97354.1 - 2.2 8.3 77.8 0.6 10.1 18.5 5.6 4 2 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PI_PP_I PF18363.1 KKF97354.1 - 2.5 8.4 8.2 14 5.9 1.3 3.3 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain APG6_N PF17675.1 KKF97354.1 - 5 7.7 72.5 0.15 12.6 9.8 6.1 2 2 2 4 4 4 0 Apg6 coiled-coil region Noc2 PF03715.13 KKF97355.1 - 4.4e-124 413.6 0.0 7.3e-124 412.9 0.0 1.4 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 KKF97355.1 - 0.0041 15.4 0.0 0.0041 15.4 0.0 3.5 2 2 1 3 3 3 1 Nop14-like family VPS28 PF03997.12 KKF97356.1 - 5e-69 231.8 0.3 6e-69 231.5 0.3 1.1 1 0 0 1 1 1 1 VPS28 protein Pacs-1 PF10254.9 KKF97356.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein MMM1 PF10296.9 KKF97357.1 - 0.00099 18.3 0.0 0.004 16.3 0.0 1.9 2 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PIP5K PF01504.18 KKF97358.1 - 5.8e-28 97.9 3.9 1.3e-20 73.8 0.2 3.1 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KKF97358.1 - 3.2e-23 82.1 0.0 4.7e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BolA PF01722.18 KKF97359.1 - 2.2e-29 101.6 1.6 2.7e-29 101.2 1.6 1.1 1 0 0 1 1 1 1 BolA-like protein NTP_transf_6 PF06042.11 KKF97359.1 - 0.12 12.3 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase AMP-binding PF00501.28 KKF97360.1 - 3.8e-57 193.8 0.0 5.2e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKF97360.1 - 5.7e-14 52.9 0.0 1.3e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.18 KKF97361.1 - 7.6e-54 181.8 0.2 1.1e-53 181.3 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Sin3a_C PF16879.5 KKF97362.1 - 6.8e-59 199.9 0.0 1.6e-58 198.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KKF97362.1 - 1e-38 131.3 0.0 2.4e-38 130.1 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 KKF97362.1 - 1.2e-24 86.2 2.7 3.7e-19 68.6 2.0 2.6 2 0 0 2 2 2 2 Paired amphipathic helix repeat TSP_NTD PF17804.1 KKF97362.1 - 0.036 14.3 0.2 0.036 14.3 0.2 3.3 4 0 0 4 4 4 0 Tail specific protease N-terminal domain Thiolase_N PF00108.23 KKF97363.1 - 1.6e-97 326.0 1.8 1.6e-97 326.0 1.8 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKF97363.1 - 1.4e-47 160.3 1.3 4.7e-47 158.7 0.5 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKF97363.1 - 0.00037 20.2 9.0 0.00042 20.0 3.1 3.0 2 2 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KKF97363.1 - 0.01 14.5 0.1 0.055 12.2 0.1 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 KKF97363.1 - 0.07 13.0 2.4 0.42 10.5 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KKF97363.1 - 0.07 13.3 0.1 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal GTP_EFTU PF00009.27 KKF97364.1 - 1.8e-43 148.4 0.0 2.5e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KKF97364.1 - 6.8e-33 113.9 7.0 1.3e-32 112.9 7.0 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KKF97364.1 - 5.1e-25 87.6 0.0 1.4e-24 86.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KKF97364.1 - 9.5e-20 70.4 0.0 2.1e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KKF97364.1 - 1.6e-08 34.5 0.1 1.9e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KKF97364.1 - 7.1e-07 29.5 0.0 1.5e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKF97364.1 - 0.00019 21.5 0.2 0.00035 20.6 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeS_assembly_P PF01883.19 KKF97365.1 - 8.3e-07 29.1 0.0 4.9e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein 2OG-FeII_Oxy PF03171.20 KKF97366.1 - 0.0096 16.4 0.0 0.034 14.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_4 PF13462.6 KKF97366.1 - 0.07 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin FRG1 PF06229.12 KKF97367.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 FRG1-like domain WD40 PF00400.32 KKF97368.1 - 2e-06 28.4 7.9 0.18 12.7 0.1 4.8 4 1 0 5 5 5 3 WD domain, G-beta repeat Pro_Al_protease PF02983.14 KKF97368.1 - 0.0092 16.0 0.2 0.021 14.9 0.2 1.6 1 0 0 1 1 1 1 Alpha-lytic protease prodomain Sel1 PF08238.12 KKF97369.1 - 1e-32 111.8 23.9 0.00012 22.6 0.1 10.5 10 0 0 10 10 10 7 Sel1 repeat TPR_6 PF13174.6 KKF97369.1 - 1.7 9.5 15.1 20 6.1 0.3 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKF97369.1 - 2.8 7.9 9.1 6.2 6.8 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat IQ PF00612.27 KKF97370.1 - 0.013 15.2 0.3 0.036 13.8 0.3 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_16 PF13191.6 KKF97371.1 - 1.5e-08 35.3 0.2 4.1e-08 33.8 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KKF97371.1 - 2.3e-05 24.4 0.1 4.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DNA_pol3_delta PF06144.13 KKF97371.1 - 0.0032 17.3 0.2 0.0058 16.4 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RsgA_GTPase PF03193.16 KKF97371.1 - 0.014 15.3 0.4 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 KKF97371.1 - 0.035 13.3 0.0 0.074 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 KKF97371.1 - 0.043 14.2 0.1 0.12 12.9 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KKF97371.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KKF97371.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KKF97371.1 - 0.31 11.3 3.0 2.9 8.2 3.0 2.3 1 1 0 1 1 1 0 AAA domain DNA_pol_A_exo1 PF01612.20 KKF97372.1 - 4.7e-43 146.9 0.5 7.4e-43 146.3 0.5 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KKF97372.1 - 1.1e-20 74.0 0.1 4.7e-20 72.1 0.1 2.2 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KKF97372.1 - 2.2e-09 37.2 0.1 6.5e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 HRDC domain Gpi1 PF05024.15 KKF97373.1 - 8.7e-76 254.2 9.9 1.7e-75 253.2 9.9 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.21 KKF97373.1 - 0.0013 18.1 0.6 0.0028 17.0 0.6 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BLOC1S3 PF15753.5 KKF97373.1 - 0.25 11.4 1.6 1.4 9.0 0.7 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Med9 PF07544.13 KKF97374.1 - 3.1e-20 72.0 0.3 6e-20 71.1 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.12 KKF97374.1 - 0.0035 17.8 4.6 0.58 10.7 0.6 2.3 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 KKF97374.1 - 0.008 16.0 1.1 0.012 15.4 1.1 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Spc29 PF17082.5 KKF97374.1 - 0.0084 16.0 0.4 0.012 15.5 0.4 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 DUF3375 PF11855.8 KKF97374.1 - 0.026 13.5 3.0 0.036 13.0 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Apt1 PF10351.9 KKF97374.1 - 0.054 12.3 1.2 0.069 12.0 1.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DivIC PF04977.15 KKF97374.1 - 0.058 13.2 1.4 0.097 12.4 1.4 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF1993 PF09351.10 KKF97374.1 - 0.094 12.9 0.4 0.17 12.1 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) SlyX PF04102.12 KKF97374.1 - 0.15 12.7 4.9 0.2 12.3 3.5 2.0 2 0 0 2 2 2 0 SlyX Med21 PF11221.8 KKF97374.1 - 0.6 10.4 8.3 1.2 9.4 8.3 1.6 1 1 0 1 1 1 0 Subunit 21 of Mediator complex iPGM_N PF06415.13 KKF97375.1 - 1.1e-74 250.5 0.0 1.7e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KKF97375.1 - 1.4e-66 224.4 0.1 1.6e-66 224.2 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KKF97375.1 - 2.1e-06 27.4 0.1 1.1e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKF97375.1 - 2.7e-05 23.9 0.1 4.5e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Prefoldin PF02996.17 KKF97376.1 - 6.5e-35 119.7 0.3 1.1e-34 118.9 0.1 1.5 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 KKF97376.1 - 0.0044 17.0 1.2 2 8.4 0.0 2.7 2 1 0 2 2 2 2 Prefoldin subunit End3 PF12761.7 KKF97376.1 - 0.0047 17.1 0.2 0.073 13.2 0.2 2.2 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 DUF1664 PF07889.12 KKF97376.1 - 0.052 13.6 0.2 7.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CRAL_TRIO PF00650.20 KKF97377.1 - 8.4e-36 123.1 0.0 1.8e-35 122.0 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKF97377.1 - 4.8e-07 29.9 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Mis14 PF08641.12 KKF97378.1 - 4.2e-17 62.7 0.5 5.3e-17 62.4 0.5 1.1 1 0 0 1 1 1 1 Kinetochore protein Mis14 like HGD-D PF06050.13 KKF97378.1 - 0.08 12.7 0.6 0.1 12.3 0.6 1.3 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component PAP1 PF08601.10 KKF97379.1 - 7.9 6.1 9.8 8.8 5.9 9.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 AAA PF00004.29 KKF97380.1 - 2.7e-45 154.0 0.7 8e-45 152.5 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKF97380.1 - 2e-10 40.5 0.5 1.1e-09 38.0 0.0 2.4 3 0 0 3 3 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KKF97380.1 - 6.9e-09 35.8 0.6 2.2e-08 34.2 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KKF97380.1 - 4.3e-08 33.5 0.0 9.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KKF97380.1 - 1.2e-07 32.3 0.3 3.7e-05 24.2 0.0 3.0 2 2 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KKF97380.1 - 3.6e-06 26.3 0.0 8.2e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KKF97380.1 - 3.9e-05 24.0 1.2 0.0088 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KKF97380.1 - 0.0002 21.1 0.0 0.00069 19.4 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KKF97380.1 - 0.00053 20.5 0.0 0.0014 19.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KKF97380.1 - 0.00065 19.3 0.1 0.0026 17.3 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 KKF97380.1 - 0.00071 19.9 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 KKF97380.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 KKF97380.1 - 0.0013 18.8 0.1 0.0055 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KKF97380.1 - 0.0014 18.7 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KKF97380.1 - 0.0014 17.9 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KKF97380.1 - 0.0018 18.6 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 KKF97380.1 - 0.0037 17.2 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 KKF97380.1 - 0.0048 16.6 0.8 0.014 15.1 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KKF97380.1 - 0.0058 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KKF97380.1 - 0.0072 16.1 0.1 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKF97380.1 - 0.0077 15.6 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KKF97380.1 - 0.0083 16.3 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KKF97380.1 - 0.0097 15.3 0.0 0.49 9.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein NACHT PF05729.12 KKF97380.1 - 0.011 15.7 0.9 0.11 12.4 0.0 2.7 3 1 0 3 3 2 0 NACHT domain AAA_24 PF13479.6 KKF97380.1 - 0.023 14.4 0.2 0.054 13.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KKF97380.1 - 0.032 14.7 0.3 5.5 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KKF97380.1 - 0.032 14.0 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KKF97380.1 - 0.041 13.7 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 KKF97380.1 - 0.043 13.7 1.2 0.33 10.8 0.0 2.6 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Viral_Hsp90 PF03225.14 KKF97380.1 - 0.048 12.2 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue ATPase PF06745.13 KKF97380.1 - 0.049 13.0 1.3 0.55 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.26 KKF97380.1 - 0.073 12.8 0.2 1.3 8.7 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KKF97380.1 - 0.083 12.4 1.4 0.27 10.8 0.1 2.2 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KKF97380.1 - 0.086 12.1 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin AAA_19 PF13245.6 KKF97380.1 - 0.12 12.7 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KKF97380.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KKF97380.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KKF97380.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Y_phosphatase PF00102.27 KKF97381.1 - 1.7e-44 152.2 0.0 1.1e-36 126.6 0.0 2.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KKF97381.1 - 0.0017 18.5 0.0 0.0078 16.3 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KKF97381.1 - 0.0046 17.0 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KKF97381.1 - 0.019 14.8 0.0 0.058 13.2 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain RCC1 PF00415.18 KKF97382.1 - 1.7e-25 89.3 10.9 4.7e-05 23.9 0.1 7.8 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KKF97382.1 - 9.5e-10 38.0 23.2 4e-06 26.5 0.1 6.7 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.15 KKF97383.1 - 7e-48 162.3 3.9 7e-48 162.3 3.9 1.8 2 0 0 2 2 2 1 Sec34-like family BUD22 PF09073.10 KKF97383.1 - 0.053 12.9 1.5 0.099 12.0 1.5 1.4 1 0 0 1 1 1 0 BUD22 ACP53EA PF06313.11 KKF97383.1 - 0.062 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Drosophila ACP53EA protein Brix PF04427.18 KKF97384.1 - 1.6e-21 77.3 0.0 2.9e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Brix domain GREB1 PF15782.5 KKF97384.1 - 0.13 9.4 1.7 0.15 9.1 1.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TLP-20 PF06088.11 KKF97384.1 - 2.3 8.1 6.7 3.9 7.3 6.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.14 KKF97384.1 - 3.1 6.0 11.6 4 5.6 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein HGTP_anticodon PF03129.20 KKF97385.1 - 4.5e-20 71.6 0.1 2.1e-19 69.5 0.0 2.3 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KKF97385.1 - 1.5e-07 31.6 0.0 2.8e-06 27.4 0.0 2.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DraK_HK_N PF18092.1 KKF97385.1 - 0.078 13.4 0.0 0.28 11.6 0.0 1.9 1 0 0 1 1 1 0 DraK Histidine Kinase N-terminal domain Pkinase PF00069.25 KKF97386.1 - 9.7e-66 221.8 8.0 9.1e-65 218.6 0.0 2.7 2 1 1 3 3 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF97386.1 - 3.2e-49 167.6 0.0 3.2e-49 167.6 0.0 1.7 2 0 0 2 2 1 1 Protein tyrosine kinase PBD PF00786.28 KKF97386.1 - 2.6e-22 78.9 0.1 2.6e-22 78.9 0.1 2.2 2 0 0 2 2 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KKF97386.1 - 4.5e-06 25.7 5.9 7.1e-06 25.1 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KKF97386.1 - 1e-05 25.0 0.0 1e-05 25.0 0.0 2.0 2 0 0 2 2 1 1 Kinase-like PH_11 PF15413.6 KKF97386.1 - 0.00082 19.8 2.9 0.00088 19.7 0.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KKF97386.1 - 0.037 14.5 0.2 0.14 12.6 0.2 2.0 1 1 0 1 1 1 0 PH domain Haspin_kinase PF12330.8 KKF97386.1 - 0.06 12.3 0.1 0.06 12.3 0.1 2.0 2 0 0 2 2 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KKF97386.1 - 0.071 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 eIF-3_zeta PF05091.12 KKF97386.1 - 1.1 8.1 12.3 1.7 7.5 12.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDRGK PF09756.9 KKF97386.1 - 1.3 8.5 22.1 2.6 7.6 22.1 1.4 1 0 0 1 1 1 0 DDRGK domain DUF4407 PF14362.6 KKF97386.1 - 3 7.1 8.2 4.9 6.4 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GREB1 PF15782.5 KKF97386.1 - 4.2 4.4 6.4 5.9 3.9 6.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer APH PF01636.23 KKF97386.1 - 6.1 6.7 13.1 0.13 12.2 0.4 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Fungal_trans_2 PF11951.8 KKF97387.1 - 5.3e-06 25.5 0.6 5.3e-06 25.5 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKF97387.1 - 0.00018 21.6 1.9 0.00018 21.6 1.9 2.4 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KKF97387.1 - 0.0025 17.9 17.9 0.0025 17.9 17.9 3.4 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 KKF97387.1 - 0.0036 16.3 12.3 0.0036 16.3 12.3 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) Ras PF00071.22 KKF97388.1 - 3.1e-53 179.7 0.0 4.5e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF97388.1 - 5.5e-32 110.5 0.0 8.9e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF97388.1 - 7.5e-12 45.1 0.0 3.2e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKF97388.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKF97388.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKF97388.1 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KKF97388.1 - 0.015 15.7 0.0 0.032 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Kri1 PF05178.12 KKF97389.1 - 1.6e-25 89.7 17.0 1.6e-25 89.7 17.0 5.6 4 3 1 5 5 5 1 KRI1-like family Kri1_C PF12936.7 KKF97389.1 - 1.9e-22 79.2 0.1 1.9e-22 79.2 0.1 4.6 4 2 2 6 6 6 1 KRI1-like family C-terminal Fungal_trans PF04082.18 KKF97390.1 - 1.5e-27 96.3 0.0 2.9e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C50 PF03568.17 KKF97391.1 - 2.6e-150 500.9 0.0 4.2e-150 500.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 KKF97391.1 - 1.8e-06 27.6 0.1 1.8e-05 24.3 0.1 2.3 1 1 0 1 1 1 1 CHAT domain TPR_6 PF13174.6 KKF97391.1 - 0.04 14.6 2.3 13 6.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKF97391.1 - 0.056 13.7 13.0 1.7 9.0 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKF97391.1 - 0.093 13.3 10.4 2.7 8.6 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat SIR2 PF02146.17 KKF97392.1 - 3.9e-06 26.9 0.0 8.2e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Sir2 family NUDIX PF00293.28 KKF97393.1 - 5e-17 62.2 0.0 1.1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KKF97393.1 - 2e-14 54.1 0.0 1e-13 51.8 0.0 2.1 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KKF97393.1 - 3.2e-08 33.1 1.6 5.4e-08 32.4 1.6 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain MFS_1 PF07690.16 KKF97394.1 - 6.8e-22 77.9 44.4 6.8e-22 77.9 44.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Tim17 PF02466.19 KKF97395.1 - 6.1e-26 91.0 3.8 9.9e-26 90.3 3.8 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family eIF-5_eIF-2B PF01873.17 KKF97397.1 - 1.9e-39 134.2 0.0 3.9e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KKF97397.1 - 1.1e-22 79.9 0.3 3.1e-22 78.5 0.3 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Neur_chan_memb PF02932.16 KKF97397.1 - 0.28 11.2 3.2 9.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Atrophin-1 PF03154.15 KKF97397.1 - 0.81 7.9 5.6 1 7.6 5.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family p450 PF00067.22 KKF97398.1 - 2.2e-47 161.9 0.0 1.6e-46 159.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Alpha-amylase PF00128.24 KKF97398.1 - 0.037 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain DUF1749 PF08538.10 KKF97399.1 - 2.3e-66 223.9 0.0 2.8e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KKF97399.1 - 3.8e-09 37.5 0.0 5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKF97399.1 - 0.0025 17.5 0.0 0.014 15.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKF97399.1 - 0.003 16.9 0.0 0.085 12.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KKF97399.1 - 0.049 13.5 0.0 0.38 10.6 0.0 2.3 3 0 0 3 3 3 0 Serine hydrolase PRCC PF10253.9 KKF97400.1 - 7.8e-34 118.3 9.6 7.8e-34 118.3 9.6 2.6 1 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF3517 PF12030.8 KKF97401.1 - 3.8e-74 249.6 0.1 6.3e-74 248.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 KKF97401.1 - 7e-25 88.0 0.1 2.6e-24 86.1 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKF97401.1 - 7e-11 42.3 0.4 7.5e-09 35.6 0.1 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-H2C2_2 PF13465.6 KKF97401.1 - 0.52 10.8 2.2 26 5.5 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-HIT PF04438.16 KKF97401.1 - 0.58 10.1 5.3 12 5.9 0.2 2.9 2 0 0 2 2 2 0 HIT zinc finger NOC3p PF07540.11 KKF97402.1 - 6e-26 90.7 0.1 2.4e-25 88.8 0.1 2.1 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KKF97402.1 - 8.3e-24 84.5 0.5 2.7e-23 82.9 0.0 2.1 1 1 1 2 2 2 1 CBF/Mak21 family PRC2_HTH_1 PF18118.1 KKF97402.1 - 9.2 7.1 10.6 0.38 11.6 0.3 3.2 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain UPF0113 PF03657.13 KKF97403.1 - 8.7e-27 93.2 0.0 1.3e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 KKF97403.1 - 3.3e-25 88.5 0.0 4.5e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 KKF97403.1 - 0.042 13.8 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 PUA domain AA_kinase PF00696.28 KKF97404.1 - 4.5e-40 137.8 1.1 7.1e-40 137.1 1.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KKF97404.1 - 1.6e-17 63.2 0.3 9.5e-17 60.7 0.0 2.2 2 0 0 2 2 2 1 PUA domain WRW PF10206.9 KKF97405.1 - 0.0017 18.7 0.1 0.0034 17.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f WW PF00397.26 KKF97405.1 - 0.0091 16.1 0.6 0.025 14.7 0.6 1.8 1 0 0 1 1 1 1 WW domain RIX1 PF08167.12 KKF97406.1 - 5.6e-56 189.3 0.1 1.7e-55 187.7 0.0 1.9 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis TPR_14 PF13428.6 KKF97407.1 - 2e-06 28.2 8.8 0.083 13.8 0.1 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKF97407.1 - 2.4e-06 27.5 0.2 0.11 12.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKF97407.1 - 1.4e-05 24.8 3.9 0.15 12.3 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKF97407.1 - 2.5e-05 24.7 1.3 0.12 12.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKF97407.1 - 0.00032 20.7 0.6 0.26 11.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKF97407.1 - 0.0029 18.2 11.5 0.18 12.5 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat SGL PF08450.12 KKF97408.1 - 5.2e-61 206.3 0.0 6.1e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region ChuX_HutX PF06228.13 KKF97408.1 - 0.083 12.7 0.0 0.97 9.2 0.0 2.2 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX Aldedh PF00171.22 KKF97409.1 - 1.3e-163 544.8 2.3 1.9e-163 544.2 2.3 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Whi5 PF08528.11 KKF97410.1 - 1.4e-09 37.4 0.3 2.6e-09 36.5 0.3 1.4 1 0 0 1 1 1 1 Whi5 like DUF5042 PF16445.5 KKF97410.1 - 0.17 10.2 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) MecA PF05389.12 KKF97411.1 - 2 8.0 18.4 4.5 6.9 3.3 2.6 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Peptidase_M18 PF02127.15 KKF97412.1 - 2e-176 587.0 0.0 3.5e-176 586.2 0.0 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KKF97412.1 - 2.6e-06 26.7 0.1 7.1e-05 22.0 0.0 2.7 2 1 0 3 3 3 1 M42 glutamyl aminopeptidase Xpo1 PF08389.12 KKF97414.1 - 4.2e-37 127.5 2.5 1.1e-36 126.2 0.1 2.9 3 1 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 KKF97414.1 - 0.00024 21.1 0.6 3.8 8.0 0.0 4.9 6 0 0 6 6 6 2 HEAT repeat DUF3336 PF11815.8 KKF97415.1 - 2.4e-43 147.2 0.3 3.8e-43 146.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KKF97415.1 - 1.1e-16 61.7 0.3 7e-16 59.0 0.1 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase Arf PF00025.21 KKF97416.1 - 7.2e-51 172.1 0.0 8e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KKF97416.1 - 3.7e-06 26.4 0.0 6.2e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 KKF97416.1 - 0.0001 21.9 0.0 0.00013 21.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF97416.1 - 0.00049 20.3 0.0 0.00067 19.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KKF97416.1 - 0.0035 16.7 0.0 0.0035 16.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKF97416.1 - 0.068 13.3 0.0 0.094 12.8 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2457 PF10446.9 KKF97417.1 - 1.1e-56 193.0 98.3 4.3e-30 105.3 6.8 4.1 2 1 2 4 4 4 4 Protein of unknown function (DUF2457) DUF2052 PF09747.9 KKF97417.1 - 0.0046 17.1 31.1 0.015 15.5 16.1 2.6 3 0 0 3 3 3 2 Coiled-coil domain containing protein (DUF2052) HJURP_mid PF12346.8 KKF97417.1 - 0.0059 17.1 0.3 0.014 15.9 0.3 1.6 1 0 0 1 1 1 1 Holliday junction recognition protein-associated repeat SDA1 PF05285.12 KKF97417.1 - 0.01 15.3 51.5 0.15 11.5 4.9 2.3 2 1 0 2 2 2 0 SDA1 CDC45 PF02724.14 KKF97417.1 - 0.098 10.9 36.9 0.021 13.1 19.1 2.4 2 0 0 2 2 2 0 CDC45-like protein CNDH2_C PF16858.5 KKF97417.1 - 0.23 11.3 29.0 0.047 13.6 12.1 2.7 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Vfa1 PF08432.10 KKF97417.1 - 0.46 10.8 27.4 0.34 11.2 12.4 3.2 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.14 KKF97417.1 - 6.8 7.1 10.2 14 6.1 4.6 2.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 CobT PF06213.12 KKF97417.1 - 7.5 5.9 43.3 4.7 6.5 26.7 2.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT ATP-synt_DE_N PF02823.16 KKF97418.1 - 2.6e-16 59.3 0.0 4.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Acyltransferase PF01553.21 KKF97419.1 - 6.8e-32 109.9 0.0 1.1e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.21 KKF97419.1 - 0.051 13.6 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Endoribonuclease L-PSP DUF4484 PF14831.6 KKF97420.1 - 5.1e-55 186.8 0.0 7.6e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) DUF2347 PF09804.9 KKF97420.1 - 1.9e-44 152.4 0.0 1.2e-43 149.7 0.0 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2347) DnaJ PF00226.31 KKF97421.1 - 1.2e-14 54.1 0.4 3.7e-14 52.6 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KKF97421.1 - 1.4e-13 50.7 0.0 3.3e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 Sec63 Brl domain Leuk-A4-hydro_C PF09127.11 KKF97421.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Enkurin PF13864.6 KKF97421.1 - 0.26 11.8 3.2 1.5 9.3 0.2 3.1 3 0 0 3 3 3 0 Calmodulin-binding DUF4045 PF13254.6 KKF97422.1 - 2.5e-78 264.6 33.8 7e-51 174.2 23.7 4.1 3 1 1 4 4 4 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KKF97422.1 - 5.2e-08 32.7 0.0 0.012 15.5 0.0 3.6 3 0 0 3 3 3 3 Gelsolin repeat Arf PF00025.21 KKF97423.1 - 1.9e-62 209.8 0.7 2.2e-62 209.6 0.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKF97423.1 - 5e-13 49.3 0.1 7.2e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKF97423.1 - 7e-12 45.2 0.0 8e-12 45.0 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KKF97423.1 - 3.8e-10 39.5 0.5 6.5e-07 28.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KKF97423.1 - 1.1e-09 38.0 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKF97423.1 - 1.4e-08 34.8 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKF97423.1 - 1.5e-07 31.0 0.0 1.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KKF97423.1 - 0.00034 20.2 0.0 0.0088 15.6 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KKF97423.1 - 0.023 14.2 0.2 0.053 13.1 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 KKF97423.1 - 0.05 13.6 0.0 0.74 9.9 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Mtc PF03820.17 KKF97424.1 - 1.5e-117 392.2 0.0 1.6e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.25 KKF97426.1 - 1.4e-09 37.7 0.1 2.3e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF97426.1 - 0.00092 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Lactamase_B_4 PF13691.6 KKF97427.1 - 5.4e-22 77.2 0.0 1.2e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KKF97427.1 - 5.5e-16 58.7 0.2 1.6e-15 57.2 0.2 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKF97427.1 - 0.00028 21.0 0.2 0.00061 19.8 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CFEM PF05730.11 KKF97428.1 - 7e-13 48.5 14.2 1.3e-12 47.7 14.2 1.4 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.16 KKF97429.1 - 1.8e-29 102.8 21.1 1.8e-29 102.8 21.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKF97429.1 - 5e-09 35.5 13.4 5e-09 35.5 13.4 3.2 2 2 1 3 3 3 1 Sugar (and other) transporter DUF1772 PF08592.11 KKF97430.1 - 5.8e-06 26.7 5.3 9.1e-06 26.0 5.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF4383 PF14325.6 KKF97430.1 - 0.19 12.0 5.6 0.13 12.5 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) adh_short_C2 PF13561.6 KKF97431.1 - 4.2e-36 124.7 1.6 7.7e-36 123.8 1.6 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKF97431.1 - 2.9e-30 105.2 1.1 4e-30 104.7 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKF97431.1 - 1.6e-09 38.0 1.9 2.4e-08 34.1 0.4 2.0 2 0 0 2 2 2 1 KR domain Tantalus PF15386.6 KKF97432.1 - 0.11 12.6 0.2 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Drosophila Tantalus-like PWI PF01480.17 KKF97434.1 - 3.8e-31 107.2 0.0 5.4e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 PWI domain Ras PF00071.22 KKF97435.1 - 4.4e-49 166.2 0.0 5.4e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF97435.1 - 1.9e-29 102.3 0.0 4.8e-29 101.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF97435.1 - 4.5e-10 39.3 0.0 5.9e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKF97435.1 - 0.00039 20.5 0.0 0.0007 19.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KKF97435.1 - 0.00051 20.4 0.1 0.0062 16.9 0.1 2.2 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KKF97435.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 KKF97435.1 - 0.02 14.4 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 KKF97435.1 - 0.027 14.4 0.1 8.3 6.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KKF97435.1 - 0.033 13.4 1.6 1.5 7.9 0.1 2.3 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 KKF97435.1 - 0.037 13.5 0.1 0.082 12.4 0.1 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KKF97435.1 - 0.077 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKF97435.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KKF97435.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKF97435.1 - 0.13 12.6 0.1 0.24 11.8 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Homeodomain PF00046.29 KKF97436.1 - 1.9e-12 46.8 4.1 4.2e-12 45.7 3.4 2.0 2 0 0 2 2 2 1 Homeodomain OSTbeta PF15048.6 KKF97436.1 - 0.0082 16.3 0.8 1.7 8.8 0.6 2.6 2 1 0 2 2 2 2 Organic solute transporter subunit beta protein NAD_kinase PF01513.21 KKF97437.1 - 1.9e-76 257.1 0.0 2.3e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.21 KKF97438.1 - 1.2e-14 54.9 0.0 2.5e-14 53.9 0.0 1.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKF97438.1 - 0.038 14.0 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PTPA PF03095.15 KKF97439.1 - 2.8e-108 361.9 0.0 3.2e-108 361.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Sugar_tr PF00083.24 KKF97440.1 - 8.4e-100 334.7 27.2 4.1e-99 332.5 28.3 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF97440.1 - 8.8e-23 80.8 37.1 5.6e-21 74.9 23.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MaoC_dehydratas PF01575.19 KKF97440.1 - 2.5e-18 65.8 0.0 5.6e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKF97440.1 - 9.3e-05 22.6 0.0 0.00057 20.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase HisG PF01634.18 KKF97441.1 - 2.8e-51 173.6 0.0 5e-51 172.8 0.0 1.4 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KKF97441.1 - 1.8e-27 95.2 0.1 4.7e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain STT3 PF02516.14 KKF97442.1 - 2.3e-141 472.1 36.0 1.5e-136 456.2 34.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.12 KKF97443.1 - 3.7e-23 81.7 0.1 4e-23 81.6 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain WD40 PF00400.32 KKF97444.1 - 1.2e-06 29.2 14.6 0.6 11.1 0.6 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat Dynein_IC2 PF11540.8 KKF97444.1 - 0.14 12.1 2.3 0.32 11.0 2.3 1.6 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 DUF726 PF05277.12 KKF97445.1 - 1.5e-96 323.3 7.0 1.9e-49 168.5 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF726) LRR_12 PF18837.1 KKF97446.1 - 8 6.2 47.3 0.34 10.6 2.1 7.7 5 2 3 8 8 8 0 Leucine-rich repeat DUF846 PF05832.12 KKF97447.1 - 1.6e-42 144.8 5.1 1.9e-42 144.6 5.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.6 KKF97447.1 - 0.061 12.7 1.0 0.083 12.2 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) EF-hand_1 PF00036.32 KKF97448.1 - 1.4e-26 90.0 8.5 3.7e-06 26.1 0.0 5.3 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 KKF97448.1 - 1.8e-23 80.4 6.5 0.00047 19.9 0.0 5.3 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 KKF97448.1 - 2.2e-23 82.5 5.1 3.5e-10 40.2 0.0 4.0 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KKF97448.1 - 1e-22 79.7 7.9 1.2e-08 34.7 0.0 5.2 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 KKF97448.1 - 1.5e-16 59.0 4.8 0.00049 19.5 0.0 4.8 5 0 0 5 5 5 4 EF hand DZR PF12773.7 KKF97449.1 - 0.056 13.5 1.5 0.14 12.2 1.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF3103 PF11301.8 KKF97449.1 - 0.19 10.5 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) Hep_59 PF07052.11 KKF97450.1 - 3.5e-17 63.1 0.0 9.2e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 Polysacc_deac_1 PF01522.21 KKF97451.1 - 4.3e-19 68.6 0.0 6.2e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 KKF97451.1 - 0.0035 16.6 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase HTH_39 PF14090.6 KKF97451.1 - 0.084 12.6 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain WD40 PF00400.32 KKF97453.1 - 7.8e-17 61.4 7.4 0.0055 17.5 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KKF97453.1 - 1e-06 27.7 3.2 5.5e-05 22.0 0.4 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KKF97453.1 - 1.2e-06 28.7 0.4 0.0012 19.1 0.1 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KKF97453.1 - 0.023 13.4 0.1 4.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like HA2 PF04408.23 KKF97454.1 - 9.4e-23 80.6 0.0 9.4e-23 80.6 0.0 3.4 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKF97454.1 - 4.3e-20 71.9 0.0 1.1e-19 70.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKF97454.1 - 4.5e-14 52.7 0.0 1.1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKF97454.1 - 3.1e-07 30.3 0.0 7.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKF97454.1 - 1.3e-05 25.5 0.0 4.5e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKF97454.1 - 9.3e-05 22.2 0.1 0.00037 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KKF97454.1 - 0.00041 19.7 0.0 0.00083 18.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KKF97454.1 - 0.00072 18.7 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KKF97454.1 - 0.0011 19.3 0.0 0.0035 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KKF97454.1 - 0.0011 19.0 0.2 0.78 9.7 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 KKF97454.1 - 0.0029 17.3 0.8 0.0081 15.8 0.1 2.1 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KKF97454.1 - 0.035 14.6 0.0 0.15 12.5 0.0 2.1 1 0 0 1 1 1 0 ABC transporter Flavi_DEAD PF07652.14 KKF97454.1 - 0.042 13.8 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_7 PF12775.7 KKF97454.1 - 0.049 13.2 0.0 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 KKF97454.1 - 0.063 13.7 0.1 0.27 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KKF97454.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATPase PF06745.13 KKF97454.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 KKF97454.1 - 0.069 13.2 0.1 0.48 10.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 KKF97454.1 - 0.071 13.0 0.1 0.74 9.7 0.0 2.7 3 0 0 3 3 3 0 Microtubule binding AAA_33 PF13671.6 KKF97454.1 - 0.1 12.8 1.3 0.28 11.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KKF97454.1 - 0.16 11.8 0.0 0.58 10.0 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Cys_Met_Meta_PP PF01053.20 KKF97455.1 - 6.4e-54 182.9 0.0 6.6e-46 156.6 0.0 2.5 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme UPF0047 PF01894.17 KKF97455.1 - 0.091 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 KAR9 PF08580.10 KKF97456.1 - 4e-136 455.3 36.7 1.5e-132 443.5 3.1 3.1 1 1 2 3 3 3 2 Yeast cortical protein KAR9 PfUIS3 PF11567.8 KKF97456.1 - 0.077 13.4 0.4 1.5 9.2 0.0 2.4 1 1 1 2 2 2 0 Plasmodium falciparum UIS3 membrane protein HIP1_clath_bdg PF16515.5 KKF97456.1 - 0.96 10.1 4.2 37 5.0 0.4 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Syntaxin-6_N PF09177.11 KKF97456.1 - 1.3 9.7 9.1 1.4 9.5 2.7 3.9 3 2 2 5 5 5 0 Syntaxin 6, N-terminal DEAD PF00270.29 KKF97458.1 - 4.6e-23 81.9 0.1 1.4e-22 80.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF97458.1 - 1.9e-19 70.0 0.0 2.2e-15 56.9 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KKF97458.1 - 8.4e-14 52.0 3.4 2.1e-13 50.8 3.4 1.7 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KKF97458.1 - 3e-11 43.1 0.0 2e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 RQC domain ResIII PF04851.15 KKF97458.1 - 2e-09 37.7 0.0 5.6e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KKF97458.1 - 3.1e-05 22.9 0.0 5.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HRDC PF00570.23 KKF97458.1 - 5.7e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 HRDC domain SecA_DEAD PF07517.14 KKF97458.1 - 0.0094 15.3 0.0 0.021 14.2 0.0 1.6 1 1 0 1 1 1 1 SecA DEAD-like domain Golgin_A5 PF09787.9 KKF97458.1 - 0.12 11.8 2.4 0.22 10.9 2.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 PcfK PF14058.6 KKF97458.1 - 0.39 11.0 5.3 0.13 12.6 0.9 2.4 2 0 0 2 2 2 0 PcfK-like protein GPI-anchored PF10342.9 KKF97459.1 - 3.5e-20 72.6 1.0 3.5e-20 72.6 1.0 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KKF97459.1 - 0.00039 20.2 0.2 0.00062 19.6 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Hamartin PF04388.12 KKF97459.1 - 0.22 10.2 10.0 0.24 10.0 10.0 1.2 1 0 0 1 1 1 0 Hamartin protein Tmemb_cc2 PF10267.9 KKF97459.1 - 1.7 7.7 2.7 2 7.5 2.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF908 PF06012.12 KKF97459.1 - 2.1 7.7 7.6 2.6 7.4 7.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PAP1 PF08601.10 KKF97459.1 - 2.1 8.0 13.7 2.6 7.7 13.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Pkinase PF00069.25 KKF97460.1 - 1.8e-34 119.3 0.0 2.9e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF97460.1 - 1.5e-15 57.2 0.0 2.4e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF97460.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KKF97460.1 - 0.0086 16.0 1.6 0.011 15.6 0.2 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKF97460.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KKF97460.1 - 0.032 13.0 0.5 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase PNP_UDP_1 PF01048.20 KKF97461.1 - 6.4e-40 136.9 1.3 7.9e-40 136.6 1.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Med13_C PF06333.12 KKF97462.1 - 3.6e-79 266.4 2.2 4.1e-79 266.2 2.2 1.0 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain Atx10homo_assoc PF09759.9 KKF97463.1 - 8.3e-11 41.8 0.0 4.5e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Fe-ADH PF00465.19 KKF97464.1 - 9.9e-56 189.1 0.1 2.6e-51 174.6 0.2 2.0 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KKF97464.1 - 1.4e-12 47.8 0.0 2.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Formyl_trans_N PF00551.19 KKF97464.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase PAP1 PF08601.10 KKF97465.1 - 3.7e-15 56.5 1.6 4.2e-15 56.4 1.6 1.0 1 0 0 1 1 1 1 Transcription factor PAP1 BSD PF03909.17 KKF97466.1 - 7e-19 67.6 0.3 7e-19 67.6 0.3 2.1 2 0 0 2 2 2 1 BSD domain Suf PF05843.14 KKF97466.1 - 0.0012 18.9 2.3 0.0012 18.9 2.3 2.3 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) WGG PF10273.9 KKF97467.1 - 7.9e-33 113.0 0.5 1.6e-32 112.0 0.5 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF4619 PF15398.6 KKF97467.1 - 0.014 14.9 0.2 0.018 14.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) RRP7 PF12923.7 KKF97467.1 - 0.018 15.1 0.7 0.027 14.6 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Herpes_pp85 PF04637.12 KKF97467.1 - 0.037 12.5 2.8 0.06 11.8 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DHC_N1 PF08385.12 KKF97467.1 - 0.25 9.9 0.1 0.29 9.7 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 GP67 PF17634.2 KKF97467.1 - 2.3 8.7 10.5 5.2 7.6 10.5 1.6 1 0 0 1 1 1 0 Gene product 67 Abhydrolase_3 PF07859.13 KKF97468.1 - 1.7e-39 135.9 0.1 1.4e-28 100.2 0.1 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKF97468.1 - 5.8e-11 41.9 0.0 1.3e-10 40.7 0.0 1.5 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KKF97468.1 - 0.036 13.3 0.0 0.089 12.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 KKF97468.1 - 0.052 12.4 0.0 0.29 9.9 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family MRP-L27 PF09809.9 KKF97469.1 - 1e-17 64.0 0.1 1.3e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF4661 PF15576.6 KKF97470.1 - 0.032 14.2 0.3 0.04 13.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) tRNA-synt_1 PF00133.22 KKF97471.1 - 1.3e-150 502.6 0.0 1.8e-150 502.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKF97471.1 - 5.8e-18 64.8 0.0 2.7e-12 46.1 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KKF97471.1 - 4.9e-15 55.8 0.0 9.2e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KKF97471.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KKF97471.1 - 0.11 11.8 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF945 PF06097.11 KKF97471.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) zf-FPG_IleRS PF06827.14 KKF97471.1 - 0.34 10.8 2.3 0.76 9.7 2.3 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Zea_mays_MuDR PF05928.11 KKF97471.1 - 0.88 9.2 2.3 1.6 8.3 0.8 2.0 2 0 0 2 2 2 0 Zea mays MURB-like protein (MuDR) DUF5627 PF18620.1 KKF97472.1 - 0.14 12.1 0.3 0.42 10.5 0.3 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5627) Ribosomal_L29 PF00831.23 KKF97473.1 - 0.017 15.1 5.1 0.037 14.0 3.7 2.2 1 1 1 2 2 2 0 Ribosomal L29 protein SF-assemblin PF06705.11 KKF97473.1 - 0.084 12.2 2.2 0.13 11.6 2.1 1.4 1 1 0 1 1 1 0 SF-assemblin/beta giardin DUF5358 PF17311.2 KKF97473.1 - 0.11 12.4 0.7 0.16 12.0 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5358) Carb_kinase PF01256.17 KKF97475.1 - 5.5e-54 183.2 0.0 6.7e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KKF97475.1 - 0.0032 16.9 0.0 0.0083 15.5 0.0 1.7 2 1 0 2 2 2 1 Phosphomethylpyrimidine kinase ATP-synt_ab PF00006.25 KKF97476.1 - 4.9e-72 242.0 0.0 7.3e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KKF97476.1 - 4.9e-48 162.6 0.9 8.1e-48 161.9 0.9 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KKF97476.1 - 1.3e-14 54.5 3.6 3.1e-14 53.2 3.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L5_C PF00673.21 KKF97477.1 - 5e-22 77.9 0.0 7.4e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KKF97477.1 - 9.9e-20 70.6 1.4 1.3e-19 70.3 0.0 1.9 3 0 0 3 3 3 1 Ribosomal protein L5 LSM PF01423.22 KKF97478.1 - 7.9e-17 60.7 0.2 1.1e-16 60.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KKF97478.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Hfq protein CDH-cyt PF16010.5 KKF97479.1 - 7.8e-26 90.9 5.2 1.5e-25 89.9 5.2 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KKF97479.1 - 5.6e-07 29.8 1.2 1.7e-06 28.3 1.2 1.8 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 KKF97479.1 - 0.0023 17.7 4.6 0.0023 17.7 4.6 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) Pkinase PF00069.25 KKF97480.1 - 2.4e-69 233.7 0.0 3.1e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKF97480.1 - 1.6e-31 109.6 0.6 2e-31 109.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKF97480.1 - 0.0012 18.2 0.0 0.0055 16.1 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KKF97480.1 - 0.014 14.4 0.2 0.024 13.6 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KKF97480.1 - 0.023 13.5 1.9 0.035 12.9 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KKF97480.1 - 0.069 13.1 0.3 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 KKF97480.1 - 0.1 13.3 0.3 0.49 11.2 0.0 2.4 2 1 0 2 2 2 0 Protein kinase C terminal domain WD40 PF00400.32 KKF97481.1 - 1.3e-16 60.6 15.0 5.5e-08 33.4 1.8 4.1 3 1 0 3 3 3 3 WD domain, G-beta repeat PRP4 PF08799.11 KKF97481.1 - 4e-14 51.8 4.8 8.4e-14 50.8 4.8 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KKF97481.1 - 0.0014 18.9 0.7 0.033 14.5 0.1 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CorA PF01544.18 KKF97483.1 - 1.3e-38 133.0 0.2 3.3e-36 125.1 0.2 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CBF PF03914.17 KKF97484.1 - 2.9e-35 121.8 0.6 4.6e-35 121.2 0.1 1.7 2 0 0 2 2 2 1 CBF/Mak21 family putAbiC PF16872.5 KKF97484.1 - 1.5 9.6 6.1 1.4 9.7 0.4 3.0 3 0 0 3 3 3 0 Putative phage abortive infection protein Mt_ATP-synt_B PF05405.14 KKF97485.1 - 1.3e-50 171.2 6.8 1.7e-50 170.8 6.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) MSC PF09402.10 KKF97486.1 - 2.8e-113 378.8 0.0 3.7e-113 378.4 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KKF97486.1 - 1e-14 53.9 0.0 1.9e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 KKF97486.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Thymopoietin protein FAD_binding_3 PF01494.19 KKF97487.1 - 9.4e-11 41.5 0.1 1.5e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KKF97487.1 - 0.0015 17.7 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Complex1_49kDa PF00346.19 KKF97488.1 - 1.6e-122 407.8 0.0 2.1e-122 407.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KKF97488.1 - 0.0045 16.0 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.26 KKF97489.1 - 1.8e-25 89.5 0.0 3.1e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KKF97489.1 - 1.4e-19 69.3 0.0 1.9e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.21 KKF97490.1 - 7.3e-60 202.3 0.0 1e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KKF97490.1 - 2.2e-28 98.2 0.4 3.7e-28 97.5 0.4 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 KKF97490.1 - 0.0018 18.8 0.1 0.01 16.4 0.0 2.3 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KKF97490.1 - 0.35 10.7 1.2 21 4.9 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Telomere_reg-2 PF10193.9 KKF97491.1 - 4.5e-31 107.5 0.1 2.1e-29 102.2 0.0 2.7 2 0 0 2 2 2 1 Telomere length regulation protein Lipase_GDSL_2 PF13472.6 KKF97491.1 - 0.11 12.9 0.0 0.63 10.4 0.0 2.2 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.25 KKF97492.1 - 2.3e-50 171.4 0.0 1.8e-47 161.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKF97492.1 - 4.1e-36 124.6 0.0 5.6e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKF97492.1 - 3.5e-05 22.8 0.0 7.2e-05 21.7 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KKF97492.1 - 9.9e-05 22.4 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKF97492.1 - 0.0018 17.6 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKF97492.1 - 0.0028 17.0 0.2 0.0076 15.6 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KKF97492.1 - 0.04 13.5 0.0 0.086 12.4 0.0 1.5 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KKF97492.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro_15 PF00723.21 KKF97493.1 - 2.8e-52 178.0 0.0 2.6e-47 161.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 TFIIF_beta_N PF17683.1 KKF97494.1 - 3.1e-28 99.1 0.0 5e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KKF97494.1 - 1.3e-27 95.7 0.3 2.1e-27 95.0 0.3 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain DUF3048_C PF17479.2 KKF97494.1 - 0.032 14.6 0.0 0.62 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain Elongin_A PF06881.11 KKF97495.1 - 0.027 15.0 0.1 0.048 14.2 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Band_7 PF01145.25 KKF97496.1 - 2.1e-22 80.0 3.4 3.2e-22 79.4 3.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family DRMBL PF07522.14 KKF97497.1 - 2.8e-28 98.3 0.0 5.6e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase SPT2 PF08243.11 KKF97497.1 - 0.41 11.2 2.3 1 9.9 2.3 1.6 1 0 0 1 1 1 0 SPT2 chromatin protein LSM PF01423.22 KKF97498.1 - 7.8e-18 63.9 0.7 9.9e-18 63.6 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KKF97498.1 - 4.4e-05 23.5 0.0 5.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 KKF97498.1 - 0.0099 15.5 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Hfq protein DUF150_C PF17384.2 KKF97498.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain LSM14 PF12701.7 KKF97498.1 - 0.015 15.4 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain WD40 PF00400.32 KKF97499.1 - 1.2e-49 165.2 30.9 1.7e-05 25.5 0.5 12.5 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKF97499.1 - 7.9e-19 67.8 7.0 0.14 12.5 0.0 10.4 6 3 5 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KKF97499.1 - 4.2e-18 65.6 0.1 8.7e-18 64.6 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KKF97499.1 - 6.4e-07 28.6 1.1 0.36 9.7 0.0 5.7 5 2 2 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KKF97499.1 - 8.6e-07 28.0 3.1 0.12 11.0 0.0 5.7 6 1 0 6 6 6 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KKF97499.1 - 7.2e-06 26.0 0.3 0.017 15.0 0.1 4.8 4 1 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KKF97499.1 - 0.00017 21.1 0.0 4.5 6.5 0.0 3.4 3 0 0 3 3 3 3 WD40-like domain Nucleoporin_N PF08801.11 KKF97499.1 - 0.0012 17.7 1.1 0.35 9.6 0.0 4.5 5 1 0 5 5 5 1 Nup133 N terminal like Frtz PF11768.8 KKF97499.1 - 0.0058 15.0 0.0 0.053 11.8 0.0 2.2 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz RAB3GAP2_N PF14655.6 KKF97499.1 - 0.044 13.0 0.1 2.3 7.4 0.0 3.3 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WW PF00397.26 KKF97500.1 - 1.1e-11 44.5 0.6 2e-11 43.8 0.6 1.4 1 0 0 1 1 1 1 WW domain FlxA PF14282.6 KKF97500.1 - 0.00066 19.6 3.2 0.00066 19.6 3.2 2.0 2 0 0 2 2 2 1 FlxA-like protein DUF812 PF05667.11 KKF97500.1 - 0.0021 17.0 7.8 0.0025 16.8 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Dehydrin PF00257.19 KKF97500.1 - 0.0044 17.6 0.9 0.0077 16.8 0.9 1.3 1 0 0 1 1 1 1 Dehydrin Gly-zipper_Omp PF13488.6 KKF97500.1 - 0.0054 16.7 3.0 0.011 15.7 3.0 1.4 1 0 0 1 1 1 1 Glycine zipper HR1 PF02185.16 KKF97500.1 - 0.018 15.2 3.2 0.018 15.2 3.2 2.1 1 1 1 2 2 2 0 Hr1 repeat Uds1 PF15456.6 KKF97500.1 - 0.021 15.0 5.0 0.035 14.3 5.0 1.3 1 0 0 1 1 1 0 Up-regulated During Septation UPF0242 PF06785.11 KKF97500.1 - 0.022 14.9 11.0 0.031 14.4 11.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4763 PF15960.5 KKF97500.1 - 0.026 13.9 8.0 0.031 13.6 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF2076 PF09849.9 KKF97500.1 - 0.026 14.6 19.0 0.16 12.0 19.0 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TarH PF02203.15 KKF97500.1 - 0.038 13.9 0.1 0.077 12.9 0.0 1.4 1 1 0 1 1 1 0 Tar ligand binding domain homologue Spc7 PF08317.11 KKF97500.1 - 0.043 12.7 15.6 0.059 12.3 15.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cwf_Cwc_15 PF04889.12 KKF97500.1 - 0.046 13.4 13.5 0.061 13.0 13.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AAA_11 PF13086.6 KKF97500.1 - 0.049 13.4 1.0 0.065 13.0 1.0 1.1 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.13 KKF97500.1 - 0.052 14.1 5.1 0.75 10.4 1.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DLP_helical PF18709.1 KKF97500.1 - 0.057 12.6 6.5 0.073 12.3 6.5 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain DUF1043 PF06295.12 KKF97500.1 - 0.074 13.1 5.8 3.1 7.8 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1043) Cep57_CLD_2 PF14197.6 KKF97500.1 - 0.11 12.6 14.8 0.33 11.1 10.7 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 AKNA PF12443.8 KKF97500.1 - 0.18 12.5 5.6 0.31 11.7 5.6 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor Cnn_1N PF07989.11 KKF97500.1 - 0.41 10.8 9.2 0.14 12.3 6.4 1.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 HSCB_C PF07743.13 KKF97500.1 - 0.5 10.9 13.5 0.91 10.1 13.5 1.4 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain XhlA PF10779.9 KKF97500.1 - 0.51 10.6 6.3 1.4 9.2 6.0 1.9 2 0 0 2 2 2 0 Haemolysin XhlA GrpE PF01025.19 KKF97500.1 - 0.52 10.0 13.1 0.87 9.2 13.0 1.5 1 1 0 1 1 1 0 GrpE AAA_23 PF13476.6 KKF97500.1 - 0.59 10.6 8.1 0.77 10.2 8.1 1.2 1 0 0 1 1 1 0 AAA domain CorA PF01544.18 KKF97500.1 - 0.6 9.4 4.6 0.8 9.0 4.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pepsin-I3 PF06394.13 KKF97500.1 - 0.94 9.7 3.4 31 4.9 4.1 2.4 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain CPP1-like PF11833.8 KKF97500.1 - 1.9 8.1 5.7 21 4.7 0.0 2.2 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Atg14 PF10186.9 KKF97500.1 - 2 7.4 5.3 2.7 7.0 5.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Calpain_inhib PF00748.19 KKF97500.1 - 2.2 8.8 10.6 0.36 11.3 6.9 1.5 2 0 0 2 2 1 0 Calpain inhibitor DUF4140 PF13600.6 KKF97500.1 - 2.8 8.4 7.0 4.8 7.7 7.0 1.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.19 KKF97500.1 - 3.8 5.3 8.3 4.9 4.9 8.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AF-4 PF05110.13 KKF97500.1 - 3.9 5.4 12.0 5.1 5.1 12.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4407 PF14362.6 KKF97500.1 - 5.9 6.2 6.9 8.7 5.6 6.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) EcsC PF12787.7 KKF97500.1 - 7.3 6.2 5.7 1.6 8.3 0.4 2.0 2 0 0 2 2 2 0 EcsC protein family Tho2 PF11262.8 KKF97500.1 - 8.3 5.5 9.0 11 5.1 9.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Peptidase_C14 PF00656.22 KKF97501.1 - 2.1e-62 211.3 0.0 2.6e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CYSTM PF12734.7 KKF97502.1 - 0.0023 18.2 53.7 1.8e+04 -5.5 53.7 4.6 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance P34-Arc PF04045.14 KKF97503.1 - 1.7e-104 348.7 1.3 2.2e-104 348.4 1.3 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc SNase PF00565.17 KKF97504.1 - 4.5e-23 81.8 0.0 5.9e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DDOST_48kD PF03345.14 KKF97504.1 - 0.12 11.2 0.3 0.17 10.7 0.3 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta Iso_dh PF00180.20 KKF97505.1 - 1.6e-122 409.0 0.0 1.1e-120 402.9 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase AAA_lid_3 PF17862.1 KKF97505.1 - 0.0039 17.0 0.1 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain DiS_P_DiS PF06750.13 KKF97506.1 - 2e-05 24.6 0.0 47 4.2 0.0 6.1 6 0 0 6 6 6 0 Bacterial Peptidase A24 N-terminal domain PQQ_3 PF13570.6 KKF97506.1 - 0.087 13.3 3.8 33 5.1 0.1 4.6 3 0 0 3 3 3 0 PQQ-like domain BH3 PF15285.6 KKF97506.1 - 0.4 10.5 11.9 27 4.7 0.0 6.3 7 0 0 7 7 7 0 Beclin-1 BH3 domain, Bcl-2-interacting DUF899 PF05988.12 KKF97506.1 - 0.46 10.0 16.2 5.7 6.4 0.2 6.2 1 1 3 5 5 5 0 Bacterial protein of unknown function (DUF899) Gal11_ABD1 PF18535.1 KKF97506.1 - 2.6 8.2 5.2 7.3 6.8 0.4 3.2 1 1 2 3 3 3 0 Gal11 activator-binding domain (ABD1) Gln-synt_C-ter PF18318.1 KKF97506.1 - 3 7.7 15.9 16 5.4 0.2 4.9 4 1 1 5 5 5 0 Glutamine synthetase C-terminal domain PIH1_CS PF18201.1 KKF97506.1 - 7.6 7.0 27.0 3.1 8.3 0.3 6.1 5 1 2 7 7 7 0 PIH1 CS-like domain dCMP_cyt_deam_1 PF00383.23 KKF97506.1 - 8.2 6.4 8.2 93 3.0 0.0 4.8 5 1 1 6 6 6 0 Cytidine and deoxycytidylate deaminase zinc-binding region MFS_1 PF07690.16 KKF97507.1 - 3.2e-27 95.4 33.2 3.2e-27 95.4 33.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily betaPIX_CC PF16523.5 KKF97508.1 - 0.0046 16.8 0.8 0.0099 15.7 0.8 1.5 1 0 0 1 1 1 1 betaPIX coiled coil Golgin_A5 PF09787.9 KKF97508.1 - 0.0084 15.6 0.8 0.014 14.8 0.8 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 TSC22 PF01166.18 KKF97508.1 - 0.0089 16.3 2.6 0.0089 16.3 2.6 1.7 2 0 0 2 2 2 1 TSC-22/dip/bun family Trypan_PARP PF05887.11 KKF97508.1 - 0.016 15.2 15.4 0.041 13.9 15.4 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Seadorna_VP6 PF07407.11 KKF97508.1 - 0.23 10.3 0.2 0.35 9.8 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein GIT_CC PF16559.5 KKF97508.1 - 6.8 6.6 8.9 0.2 11.5 1.9 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Aminotran_4 PF01063.19 KKF97509.1 - 7.1e-17 62.0 0.1 1.7e-16 60.7 0.1 1.6 1 1 0 1 1 1 1 Amino-transferase class IV DUF3236 PF11576.8 KKF97509.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) TPR_1 PF00515.28 KKF97510.1 - 4.2e-46 153.0 11.5 7.5e-06 25.6 0.1 11.3 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 KKF97510.1 - 2e-44 146.1 12.2 1.1e-05 25.2 0.1 11.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_17 PF13431.6 KKF97510.1 - 6.4e-28 95.1 2.1 4e-05 23.7 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KKF97510.1 - 4.2e-25 85.8 6.9 0.0047 17.0 0.0 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 KKF97510.1 - 1.5e-24 86.3 6.4 2.3e-05 24.9 0.1 6.9 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KKF97510.1 - 4.1e-23 80.8 14.4 3.5e-05 23.4 0.0 8.6 6 2 3 9 9 9 5 TPR repeat TPR_12 PF13424.6 KKF97510.1 - 3.1e-19 69.0 18.8 0.0016 18.7 1.7 8.0 4 3 4 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 KKF97510.1 - 2.9e-18 66.2 13.5 0.00039 20.9 0.6 7.1 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKF97510.1 - 9.9e-15 54.0 15.2 0.017 15.9 0.0 9.3 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKF97510.1 - 9.4e-13 47.2 16.5 0.1 12.7 0.1 9.8 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KKF97510.1 - 2.4e-12 46.8 9.5 4.6e-06 26.7 0.0 5.9 6 1 1 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKF97510.1 - 1.5e-09 37.9 8.9 1.2 9.4 0.0 5.9 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 KKF97510.1 - 1.3e-07 30.9 3.0 0.073 12.5 0.0 5.5 6 0 0 6 6 6 2 SHNi-TPR TPR_6 PF13174.6 KKF97510.1 - 3e-07 30.6 19.0 0.2 12.4 0.0 8.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKF97510.1 - 8e-07 28.7 20.5 0.28 11.1 0.4 8.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_15 PF13429.6 KKF97510.1 - 4.9e-06 26.0 6.0 0.083 12.1 0.1 4.9 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KKF97510.1 - 1.5e-05 24.6 0.4 5.2e-05 22.8 0.1 2.0 2 1 0 2 2 2 1 MalT-like TPR region DUF3856 PF12968.7 KKF97510.1 - 0.00054 20.0 7.1 4.2 7.4 0.1 5.8 3 2 0 4 4 4 2 Domain of Unknown Function (DUF3856) MIT PF04212.18 KKF97510.1 - 0.011 15.8 17.8 5.2 7.2 0.5 6.6 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain MAS20 PF02064.15 KKF97510.1 - 0.027 14.6 4.8 25 5.0 0.0 4.4 4 1 1 5 5 4 0 MAS20 protein import receptor TPR_20 PF14561.6 KKF97510.1 - 0.04 14.2 10.5 1.6 9.1 0.1 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KKF97510.1 - 0.067 12.8 0.1 3.5 7.3 0.2 3.1 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) preATP-grasp_3 PF18301.1 KKF97510.1 - 0.13 12.6 0.4 1.8 8.9 0.2 2.8 2 0 0 2 2 2 0 pre ATP-grasp 3 domain TPR_4 PF07721.14 KKF97510.1 - 0.48 11.2 7.2 69 4.5 0.0 5.9 6 1 1 7 7 4 0 Tetratricopeptide repeat Sel1 PF08238.12 KKF97510.1 - 0.65 10.8 4.1 17 6.2 0.1 3.9 4 0 0 4 4 2 0 Sel1 repeat Filament PF00038.21 KKF97511.1 - 0.0071 16.0 26.4 0.0071 16.0 26.4 4.1 2 1 2 4 4 4 2 Intermediate filament protein Shugoshin_N PF07558.11 KKF97511.1 - 0.0091 15.8 2.5 9.6 6.2 0.1 4.0 3 0 0 3 3 3 2 Shugoshin N-terminal coiled-coil region BRE1 PF08647.11 KKF97511.1 - 0.012 15.7 15.3 0.012 15.7 15.3 6.6 4 2 2 6 6 6 0 BRE1 E3 ubiquitin ligase PspA_IM30 PF04012.12 KKF97511.1 - 0.25 10.9 0.1 0.25 10.9 0.1 6.1 4 1 2 6 6 6 0 PspA/IM30 family Cob_adeno_trans PF01923.18 KKF97511.1 - 0.77 9.9 16.0 0.42 10.8 0.9 3.6 1 1 2 3 3 3 0 Cobalamin adenosyltransferase SlyX PF04102.12 KKF97511.1 - 0.88 10.2 46.4 1.7 9.3 5.1 7.3 5 2 2 7 7 7 0 SlyX TMEM192 PF14802.6 KKF97511.1 - 3.1 6.9 3.9 53 2.8 0.0 3.0 3 0 0 3 3 3 0 TMEM192 family UPF1_Zn_bind PF09416.10 KKF97512.1 - 5.9e-70 234.1 2.8 9.9e-70 233.4 2.8 1.4 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 KKF97512.1 - 4.8e-54 183.9 1.8 1.3e-27 97.3 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 KKF97512.1 - 2e-25 89.6 0.0 3.8e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF5599 PF18141.1 KKF97512.1 - 9.2e-25 86.7 0.0 1.8e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KKF97512.1 - 5.5e-16 58.8 0.1 3.3e-15 56.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF97512.1 - 7.8e-12 45.7 0.0 1.9e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KKF97512.1 - 1.1e-06 28.8 0.0 2.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KKF97512.1 - 2.6e-05 23.9 0.0 0.034 13.7 0.0 2.3 1 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain ATPase PF06745.13 KKF97512.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.9 KKF97512.1 - 0.00079 18.8 0.0 0.0037 16.6 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KKF97512.1 - 0.00083 18.6 0.1 0.86 8.7 0.0 2.8 2 1 1 3 3 3 2 PIF1-like helicase Helicase_RecD PF05127.14 KKF97512.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Helicase DEAD PF00270.29 KKF97512.1 - 0.0031 17.3 0.2 0.0091 15.8 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 KKF97512.1 - 0.013 15.0 0.0 0.056 12.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 KKF97512.1 - 0.054 13.9 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KKF97512.1 - 0.082 13.3 0.3 0.22 12.0 0.3 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 KKF97512.1 - 0.095 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_26 PF13500.6 KKF97512.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KKF97512.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Brix PF04427.18 KKF97513.1 - 7.5e-05 22.9 0.0 0.23 11.5 0.1 2.2 1 1 1 2 2 2 2 Brix domain Syntaxin PF00804.25 KKF97514.1 - 1e-23 84.1 7.1 1e-23 84.1 7.1 1.6 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 KKF97514.1 - 2.4e-08 33.8 7.2 2.5e-08 33.8 0.2 3.0 3 0 0 3 3 3 1 SNARE domain Mer2 PF09074.10 KKF97514.1 - 0.11 12.3 6.3 0.068 13.0 3.2 2.0 1 1 1 2 2 2 0 Mer2 FapA PF03961.13 KKF97514.1 - 0.2 10.2 6.5 0.082 11.5 2.7 2.1 1 1 1 3 3 3 0 Flagellar Assembly Protein A Syntaxin_2 PF14523.6 KKF97514.1 - 0.28 11.6 7.4 0.69 10.3 5.3 2.2 2 0 0 2 2 2 0 Syntaxin-like protein DUF16 PF01519.16 KKF97514.1 - 0.33 11.4 5.7 6 7.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 LMBR1 PF04791.16 KKF97514.1 - 3.8 6.3 9.1 7.2 5.4 8.7 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein Glyco_hydro_47 PF01532.20 KKF97515.1 - 2.7e-159 530.9 0.0 3.1e-159 530.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Biotin_lipoyl_2 PF13533.6 KKF97515.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like DnaJ PF00226.31 KKF97516.1 - 5.4e-21 74.5 0.2 1e-20 73.6 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain CAF20 PF17052.5 KKF97516.1 - 0.047 13.8 0.3 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Cap associated factor Porin_3 PF01459.22 KKF97517.1 - 2.1e-67 227.4 6.4 2.3e-67 227.3 6.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.21 KKF97518.1 - 6.5e-94 315.5 0.1 3.1e-54 185.0 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KKF97518.1 - 6.4e-40 135.9 0.0 9.9e-40 135.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KKF97518.1 - 1.6e-31 109.3 0.0 2.8e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KKF97518.1 - 6.2e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KKF97518.1 - 0.00031 19.9 0.0 0.0012 18.0 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Pex19 PF04614.12 KKF97519.1 - 1.4e-76 257.5 8.9 2.1e-76 257.0 8.9 1.2 1 0 0 1 1 1 1 Pex19 protein family KMP11 PF03037.16 KKF97519.1 - 0.042 14.6 3.6 8.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 GET2 PF08690.10 KKF97519.1 - 0.048 13.3 13.9 0.055 13.2 5.8 2.6 1 1 1 2 2 2 0 GET complex subunit GET2 ABC1 PF03109.16 KKF97521.1 - 1.3e-34 118.9 0.0 2.6e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Rad52_Rad22 PF04098.15 KKF97522.1 - 7.5e-59 198.0 0.0 1.1e-58 197.4 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Cut8 PF08559.10 KKF97523.1 - 8.2e-51 172.9 0.0 9.3e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein VirB7 PF17413.2 KKF97523.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 RRM_1 PF00076.22 KKF97524.1 - 2.4e-19 68.9 2.1 2.1e-12 46.7 0.0 3.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKF97524.1 - 0.00064 19.8 0.0 0.2 11.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 KKF97524.1 - 0.0025 17.6 0.0 0.88 9.4 0.0 2.6 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KKF97524.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Gln-synt_C PF00120.24 KKF97525.1 - 2.1e-64 217.7 0.0 3e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Ribosomal_L24e PF01246.20 KKF97526.1 - 6.2e-31 106.4 5.7 6.2e-31 106.4 5.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e COPI_C PF06957.11 KKF97526.1 - 5 5.8 10.8 6.7 5.3 10.8 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Ku PF02735.16 KKF97527.1 - 3.3e-30 105.3 0.0 6.1e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KKF97527.1 - 4.5e-30 104.3 0.0 1.3e-29 102.7 0.0 1.9 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 KKF97527.1 - 6.7e-08 32.5 0.3 1e-07 31.9 0.3 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KKF97527.1 - 3.7e-05 24.1 0.1 0.00016 22.0 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain Pam16 PF03656.13 KKF97528.1 - 1e-05 25.6 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KKF97528.1 - 4.6e-05 23.5 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 KKF97528.1 - 0.00099 18.7 0.7 0.00099 18.7 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3918) Ad_Cy_reg PF16701.5 KKF97528.1 - 0.053 13.3 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain TMP_2 PF06791.13 KKF97528.1 - 0.082 12.6 0.1 0.088 12.5 0.1 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF4149 PF13664.6 KKF97529.1 - 1.6e-24 86.2 2.3 2.1e-24 85.8 1.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 KKF97529.1 - 0.0014 19.0 0.1 0.002 18.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Jacalin PF01419.17 KKF97530.1 - 2.2e-07 30.8 0.2 4.9e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain NACHT_N PF17100.5 KKF97531.1 - 8.8e-27 94.4 10.4 3e-16 60.0 0.2 3.3 2 1 1 3 3 3 2 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 KKF97531.1 - 2.4e-19 69.3 5.8 2.3e-09 37.7 0.3 3.1 3 0 0 3 3 2 2 WD domain, G-beta repeat NACHT PF05729.12 KKF97531.1 - 5.2e-08 33.0 2.7 1.1e-05 25.4 0.0 2.9 2 1 1 3 3 3 2 NACHT domain ANAPC4_WD40 PF12894.7 KKF97531.1 - 1.7e-06 28.2 0.1 0.0062 16.8 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_19 PF13245.6 KKF97531.1 - 0.0021 18.4 0.1 0.027 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KKF97531.1 - 0.0033 16.7 0.2 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KKF97531.1 - 0.018 15.0 1.5 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KKF97531.1 - 0.053 13.3 0.0 0.053 13.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain ParE_toxin PF05016.15 KKF97531.1 - 0.18 12.5 1.3 4.9 7.8 0.1 3.1 4 0 0 4 4 4 0 ParE toxin of type II toxin-antitoxin system, parDE RNA_helicase PF00910.22 KKF97531.1 - 0.21 12.0 1.4 0.45 10.9 0.1 2.4 2 1 0 2 2 2 0 RNA helicase CP12 PF02672.15 KKF97531.1 - 0.32 11.8 4.3 1.3 9.8 4.3 2.1 1 0 0 1 1 1 0 CP12 domain Sugar_tr PF00083.24 KKF97533.1 - 6.5e-101 338.4 11.8 7.4e-101 338.2 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKF97533.1 - 1.8e-34 119.3 26.8 1.4e-28 99.9 6.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKF97533.1 - 4.1e-05 22.3 14.5 0.0079 14.8 4.9 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 KKF97533.1 - 0.0024 16.4 0.7 0.0024 16.4 0.7 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KKF97533.1 - 0.0076 14.6 0.3 0.2 9.9 0.3 2.4 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Alpha-L-AF_C PF06964.12 KKF97534.1 - 5.6e-25 88.4 0.0 9.7e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Ehrlichia_rpt PF09528.10 KKF97535.1 - 0.019 14.4 1.0 0.047 13.2 1.0 1.7 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Pkinase PF00069.25 KKF97536.1 - 4.4e-16 59.0 0.0 6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KKF97536.1 - 6.9e-05 22.9 2.4 0.00018 21.5 0.3 2.3 1 1 2 3 3 3 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KKF97536.1 - 7.7e-05 22.1 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_ab PF00006.25 KKF97537.1 - 3.2e-66 223.0 0.0 4.5e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KKF97537.1 - 6.4e-14 52.2 1.1 1.3e-13 51.3 1.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 KKF97537.1 - 0.0059 16.7 0.0 0.014 15.6 0.0 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5535) HAS-barrel PF09378.10 KKF97537.1 - 0.037 14.2 0.3 0.087 13.0 0.3 1.6 1 0 0 1 1 1 0 HAS barrel domain HMGL-like PF00682.19 KKF97538.1 - 8.5e-32 110.7 0.1 1e-31 110.5 0.1 1.0 1 0 0 1 1 1 1 HMGL-like DUF362 PF04015.12 KKF97538.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF362) Diphthamide_syn PF01866.17 KKF97539.1 - 1.2e-117 392.7 0.0 1.5e-117 392.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ribosomal_S6e PF01092.19 KKF97540.1 - 5.6e-58 194.4 0.2 1.1e-57 193.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e HECT PF00632.25 KKF97541.1 - 3e-96 322.5 0.6 4.8e-96 321.9 0.1 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KKF97541.1 - 3.7e-22 77.0 19.1 8.8e-08 31.3 0.1 3.9 3 0 0 3 3 3 3 Ubiquitin binding region DUF908 PF06012.12 KKF97542.1 - 3.5e-38 132.0 1.8 4.3e-38 131.7 1.8 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) GDPD PF03009.17 KKF97542.1 - 0.043 13.5 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family RabGAP-TBC PF00566.18 KKF97543.1 - 2.8e-49 167.7 0.4 1.4e-47 162.1 0.1 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 KKF97543.1 - 1.9e-06 27.9 18.7 2.9e-05 24.2 5.4 3.3 1 1 1 2 2 2 2 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 KKF97543.1 - 0.0071 16.6 14.1 0.0071 16.6 14.1 3.7 3 2 1 4 4 4 1 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KKF97543.1 - 2 8.5 9.0 0.46 10.5 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4094 PF13334.6 KKF97543.1 - 3.8 8.0 5.6 1.4 9.4 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) IFP_35_N PF07334.13 KKF97543.1 - 4.7 7.3 5.9 2.3 8.3 2.3 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PspB PF06667.12 KKF97543.1 - 7.8 6.6 7.3 1.1 9.4 1.4 2.6 2 0 0 2 2 2 0 Phage shock protein B TolA_bind_tri PF16331.5 KKF97543.1 - 9 6.4 11.4 0.3 11.2 2.9 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation Ribosomal_S8e PF01201.22 KKF97544.1 - 3.1e-56 189.3 0.7 3.6e-56 189.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Steroid_dh PF02544.16 KKF97545.1 - 2.7e-32 111.8 0.4 4.6e-32 111.1 0.4 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KKF97545.1 - 0.0023 17.5 3.3 0.0049 16.4 3.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KKF97545.1 - 0.012 16.0 1.2 0.034 14.5 0.1 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase Ubiquitin_4 PF18036.1 KKF97545.1 - 0.092 12.8 0.1 2.9 8.0 0.0 2.3 1 1 0 2 2 2 0 Ubiquitin-like domain SOG2 PF10428.9 KKF97546.1 - 1.2e-65 222.7 14.1 1.2e-65 222.7 1.0 3.1 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.6 KKF97546.1 - 6.8e-20 70.6 5.7 3.5e-10 39.5 0.8 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KKF97546.1 - 2.2e-14 53.4 8.2 6.7e-06 26.4 1.5 4.4 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKF97546.1 - 6e-05 23.0 4.6 11 7.0 0.2 5.8 5 0 0 5 5 5 1 Leucine Rich Repeat DUF2408 PF10303.9 KKF97546.1 - 0.0022 18.6 0.0 0.015 15.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) LRR_6 PF13516.6 KKF97546.1 - 0.036 14.1 10.9 0.35 11.0 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich repeat HSP70 PF00012.20 KKF97547.1 - 1.4e-256 852.4 4.9 1.6e-256 852.3 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKF97547.1 - 1.9e-18 66.4 0.0 1.5e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KKF97547.1 - 0.0013 19.1 1.7 2 8.9 0.1 3.4 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 KKF97547.1 - 0.003 17.3 0.0 0.0085 15.8 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KKF97547.1 - 0.0099 15.4 0.0 0.36 10.3 0.0 2.4 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Actin PF00022.19 KKF97547.1 - 0.014 14.0 0.0 0.63 8.6 0.0 2.3 2 0 0 2 2 2 0 Actin Hydantoinase_A PF01968.18 KKF97547.1 - 0.04 13.2 0.1 0.074 12.3 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 KKF97547.1 - 0.048 12.9 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 StbA protein FAM91_C PF14648.6 KKF97547.1 - 0.19 10.5 0.3 0.4 9.5 0.2 1.5 2 0 0 2 2 2 0 FAM91 C-terminus PMBR PF09373.10 KKF97547.1 - 0.31 11.3 1.1 0.68 10.2 0.0 2.2 2 0 0 2 2 2 0 Pseudomurein-binding repeat DUF3128 PF11326.8 KKF97548.1 - 7.7e-24 83.9 2.4 1.3e-23 83.2 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) RNA12 PF10443.9 KKF97549.1 - 3.3e-141 471.0 1.4 5.9e-141 470.2 0.0 1.9 2 0 0 2 2 2 1 RNA12 protein ATPase_2 PF01637.18 KKF97549.1 - 4.8e-09 36.5 0.1 2.6e-07 30.8 0.1 3.0 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KKF97549.1 - 4.4e-05 23.2 0.0 0.0002 21.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 KKF97549.1 - 0.00022 21.7 0.3 0.0013 19.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF2487 PF10673.9 KKF97549.1 - 0.01 15.9 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) AAA_14 PF13173.6 KKF97549.1 - 0.022 14.8 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKF97549.1 - 0.039 13.5 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1192 PF06698.11 KKF97549.1 - 0.044 13.8 3.2 32 4.7 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) AAA_24 PF13479.6 KKF97549.1 - 0.084 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.14 KKF97549.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer AAA_22 PF13401.6 KKF97549.1 - 0.14 12.4 0.0 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKF97549.1 - 0.16 11.2 0.1 6.6 6.0 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin Chorion_S16 PF05836.12 KKF97549.1 - 4.9 7.4 6.7 12 6.2 0.2 3.5 3 0 0 3 3 3 0 Chorion protein S16 CENP-C_C PF11699.8 KKF97550.1 - 9.5e-33 112.3 0.1 1.5e-32 111.6 0.1 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 KKF97550.1 - 4.8e-30 105.0 1.9 4.8e-30 105.0 1.9 3.2 1 1 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 KKF97550.1 - 1.4e-08 34.4 0.0 2.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KKF97550.1 - 0.091 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin RNase_HII PF01351.18 KKF97551.1 - 1.2e-44 152.5 0.0 3.3e-44 151.1 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease HII RHD3 PF05879.12 KKF97552.1 - 2.4e-301 1001.4 0.0 2.9e-301 1001.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KKF97552.1 - 7.6e-08 31.9 0.1 1.3e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KKF97552.1 - 2.5e-05 24.4 0.0 5.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KKF97552.1 - 0.00012 22.1 0.0 0.00034 20.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KKF97552.1 - 0.00014 22.2 1.2 0.0005 20.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AbiEi_3_N PF17194.4 KKF97552.1 - 0.06 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Septin PF00735.18 KKF97552.1 - 0.061 12.6 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Septin RdRP PF05183.12 KKF97553.1 - 2.2e-184 614.4 0.0 2.8e-184 614.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Hexokinase_2 PF03727.16 KKF97554.1 - 4.2e-66 222.8 0.1 6.9e-51 173.0 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KKF97554.1 - 5.8e-59 199.3 0.0 1.1e-58 198.4 0.0 1.5 1 0 0 1 1 1 1 Hexokinase WD40 PF00400.32 KKF97554.1 - 2.6e-12 47.0 11.4 0.28 12.1 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Sigma70_r1_2 PF00140.20 KKF97554.1 - 0.14 12.2 2.7 0.3 11.1 2.7 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 AAA PF00004.29 KKF97556.1 - 1.4e-15 57.9 0.0 2.5e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KKF97556.1 - 2.5e-15 56.7 0.0 7.4e-15 55.1 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KKF97556.1 - 5.6e-12 45.7 0.0 2.8e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KKF97556.1 - 9.4e-09 35.5 0.0 1.5e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KKF97556.1 - 1.7e-07 31.5 0.1 5.8e-07 29.8 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 KKF97556.1 - 8.5e-07 28.9 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 KKF97556.1 - 5e-06 26.4 0.0 1.4e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKF97556.1 - 8.7e-06 26.2 0.0 3.8e-05 24.1 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KKF97556.1 - 9.5e-06 25.9 0.0 7e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KKF97556.1 - 1.6e-05 24.9 0.2 0.00014 21.7 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KKF97556.1 - 2.2e-05 24.4 0.2 7e-05 22.8 0.1 1.9 1 1 1 2 2 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KKF97556.1 - 2.7e-05 24.0 0.0 5.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KKF97556.1 - 0.00013 21.2 0.0 0.00024 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KKF97556.1 - 0.0002 21.7 0.4 0.00071 19.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KKF97556.1 - 0.00025 20.8 0.0 0.00069 19.4 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KKF97556.1 - 0.00045 20.1 0.1 0.0036 17.1 0.1 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKF97556.1 - 0.00046 20.2 0.0 0.00096 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKF97556.1 - 0.0012 19.4 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KKF97556.1 - 0.0012 18.3 0.1 0.0063 15.9 0.1 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KKF97556.1 - 0.0041 16.6 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 KKF97556.1 - 0.0042 16.7 0.0 0.17 11.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 KKF97556.1 - 0.0046 16.7 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.15 KKF97556.1 - 0.0075 16.3 0.0 0.038 14.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 KKF97556.1 - 0.0079 15.6 0.0 0.064 12.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_28 PF13521.6 KKF97556.1 - 0.011 16.0 0.1 0.031 14.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.9 KKF97556.1 - 0.015 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KKF97556.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KKF97556.1 - 0.036 14.6 0.0 0.06 13.9 0.0 1.4 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KKF97556.1 - 0.04 13.8 0.0 0.084 12.8 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KKF97556.1 - 0.096 13.1 0.0 0.22 11.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase TAFII28 PF04719.14 KKF97556.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TIP49_C PF17856.1 KKF97556.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 TIP49 AAA-lid domain DEAD PF00270.29 KKF97556.1 - 0.12 12.1 0.1 1 9.1 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase Fringe PF02434.16 KKF97557.1 - 0.00087 18.8 2.6 0.0029 17.1 1.2 2.3 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 KKF97557.1 - 0.02 14.7 0.1 0.059 13.2 0.0 1.8 1 1 0 1 1 1 0 Galactosyltransferase PAN_4 PF14295.6 KKF97557.1 - 0.046 13.6 2.1 0.12 12.3 2.1 1.7 1 0 0 1 1 1 0 PAN domain RGS PF00615.19 KKF97557.1 - 0.11 12.7 0.4 0.25 11.6 0.1 1.7 2 0 0 2 2 2 0 Regulator of G protein signaling domain NACHT PF05729.12 KKF97558.1 - 1.7e-19 70.3 0.0 2.6e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KKF97558.1 - 0.0018 18.6 0.0 0.0043 17.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKF97558.1 - 0.0024 18.2 0.0 0.0054 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKF97558.1 - 0.0029 18.0 0.0 0.0064 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Mo25 PF08569.11 KKF97558.1 - 0.028 13.8 0.1 0.07 12.5 0.0 1.6 2 0 0 2 2 2 0 Mo25-like GvpD PF07088.11 KKF97558.1 - 0.058 12.0 0.0 0.092 11.3 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein Patatin PF01734.22 KKF97558.1 - 0.061 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase Ferric_reduct PF01794.19 KKF97559.1 - 3.2e-10 40.2 0.2 3.2e-10 40.2 0.2 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component SRP54 PF00448.22 KKF97560.1 - 2.5e-75 252.4 4.1 3.1e-75 252.1 1.4 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KKF97560.1 - 2.9e-30 104.8 4.6 2.9e-30 104.8 4.6 4.1 3 2 2 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.19 KKF97560.1 - 5.5e-14 52.1 0.0 1.5e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 KKF97560.1 - 4.8e-07 30.0 0.0 1.1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KKF97560.1 - 9.8e-07 28.5 0.9 7.3e-06 25.7 0.9 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KKF97560.1 - 2.1e-05 25.0 0.9 7.4e-05 23.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKF97560.1 - 0.00032 21.1 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KKF97560.1 - 0.0005 19.9 0.0 0.0018 18.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KKF97560.1 - 0.00074 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 KKF97560.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ResIII PF04851.15 KKF97560.1 - 0.0021 18.1 0.8 0.01 15.8 0.8 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit MeaB PF03308.16 KKF97560.1 - 0.0033 16.5 0.1 0.0033 16.5 0.1 2.8 2 1 0 2 2 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KKF97560.1 - 0.0034 17.5 0.0 0.0096 16.0 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 KKF97560.1 - 0.0054 16.4 0.3 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 KKF97560.1 - 0.0056 17.2 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KKF97560.1 - 0.0077 16.3 0.4 0.055 13.5 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KKF97560.1 - 0.011 15.6 0.2 0.033 14.0 0.1 1.9 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein MobB PF03205.14 KKF97560.1 - 0.012 15.5 0.0 0.057 13.3 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 KKF97560.1 - 0.012 15.8 0.0 0.036 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKF97560.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KKF97560.1 - 0.016 15.5 0.1 0.039 14.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KKF97560.1 - 0.023 14.1 0.7 3.3 7.1 0.9 3.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 KKF97560.1 - 0.042 13.8 0.8 0.65 9.9 0.8 2.3 1 1 0 1 1 1 0 NTPase AAA_31 PF13614.6 KKF97560.1 - 0.047 13.6 0.2 0.3 11.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KKF97560.1 - 0.053 12.8 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_24 PF13479.6 KKF97560.1 - 0.057 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KKF97560.1 - 0.062 13.7 0.4 0.24 11.8 0.2 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 KKF97560.1 - 0.077 12.4 0.0 0.24 10.8 0.0 1.8 1 0 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.27 KKF97560.1 - 0.097 13.2 0.8 0.24 11.9 0.1 2.1 2 1 0 2 2 2 0 ABC transporter DJ-1_PfpI PF01965.24 KKF97561.1 - 1.5e-14 54.1 0.0 3.6e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KKF97561.1 - 7.8e-06 25.7 0.0 2.3e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 ThiJ/PfpI family-like Catalase_C PF18011.1 KKF97561.1 - 0.0066 16.1 0.1 0.038 13.6 0.0 2.0 2 0 0 2 2 2 1 C-terminal domain found in long catalases GATase_3 PF07685.14 KKF97561.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KKF97561.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DUF1290 PF06947.12 KKF97561.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) Peptidase_C26 PF07722.13 KKF97561.1 - 0.16 11.7 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase C26 DUF4306 PF14154.6 KKF97561.1 - 0.19 11.9 0.0 0.96 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) MFS_1 PF07690.16 KKF97562.1 - 9.1e-12 44.6 31.1 9.1e-12 44.6 31.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.11 KKF97562.1 - 3.5 7.1 8.3 13 5.2 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) TAF6_C PF07571.13 KKF97563.1 - 1.7e-27 95.5 0.1 6e-27 93.8 0.0 1.9 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KKF97563.1 - 1.2e-19 70.2 0.0 3.2e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 KKF97563.1 - 0.00067 19.6 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Sdh_cyt PF01127.22 KKF97564.1 - 2.3e-16 59.9 2.9 2.8e-16 59.6 2.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PLU-1 PF08429.11 KKF97565.1 - 1.1e-92 310.9 15.7 3.5e-90 302.6 15.3 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KKF97565.1 - 7.5e-42 142.4 0.3 1.8e-41 141.2 0.3 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KKF97565.1 - 4.4e-20 72.1 0.1 1.1e-19 70.8 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KKF97565.1 - 3.2e-17 62.2 29.5 1.8e-10 40.5 6.3 3.6 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 KKF97565.1 - 1.9e-16 59.7 1.4 4.3e-16 58.6 1.4 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 KKF97565.1 - 2.3e-12 47.1 5.0 7e-12 45.5 5.0 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger PHD_4 PF16866.5 KKF97565.1 - 0.00012 22.1 23.2 0.0011 19.0 7.2 3.2 2 1 1 3 3 3 2 PHD-finger zf-Sec23_Sec24 PF04810.15 KKF97565.1 - 0.025 14.6 0.9 0.15 12.1 0.1 2.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger PHD_2 PF13831.6 KKF97565.1 - 0.079 12.5 13.0 0.02 14.4 1.3 2.9 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 KKF97565.1 - 0.26 10.9 9.4 0.4 10.3 1.2 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 KKF97565.1 - 0.28 11.6 22.5 0.12 12.7 6.9 3.0 2 0 0 2 2 2 0 Ring finger domain GIDA_assoc PF13932.6 KKF97565.1 - 2.7 8.1 8.0 0.4 10.8 1.8 2.3 1 1 1 2 2 2 0 GidA associated domain C1_1 PF00130.22 KKF97565.1 - 3.7 7.5 16.8 0.97 9.4 0.6 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rubredoxin PF00301.20 KKF97565.1 - 9.5 6.3 9.5 47 4.1 0.2 3.5 2 1 0 2 2 2 0 Rubredoxin DUF3449 PF11931.8 KKF97566.1 - 6.1e-76 254.3 1.6 1.3e-75 253.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KKF97566.1 - 1.1e-24 86.8 0.3 2.1e-24 85.8 0.3 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KKF97566.1 - 2.4e-11 43.3 0.5 4.6e-11 42.4 0.5 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KKF97566.1 - 9.6e-08 32.2 0.8 1.1e-05 25.6 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKF97566.1 - 3.5e-06 27.1 0.1 3.5e-06 27.1 0.1 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PRP9_N PF16958.5 KKF97566.1 - 2.9e-05 24.1 9.7 0.024 14.7 1.4 3.5 2 1 1 3 3 3 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 KKF97566.1 - 0.023 15.0 0.2 0.6 10.5 0.1 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KKF97566.1 - 0.037 14.8 0.8 9.2 7.4 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KKF97566.1 - 0.38 11.3 3.6 1.1 9.8 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.29 KKF97567.1 - 3e-42 144.4 0.1 4.9e-42 143.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF97567.1 - 1.4e-33 115.6 0.0 5.1e-33 113.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KKF97567.1 - 0.00041 20.1 0.1 0.0006 19.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKF97567.1 - 0.002 18.5 0.1 0.014 15.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KKF97567.1 - 0.0025 17.9 0.0 0.0047 16.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KKF97567.1 - 0.042 13.8 0.2 0.15 12.1 0.2 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain TniB PF05621.11 KKF97567.1 - 0.065 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KKF97567.1 - 0.073 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KKF97567.1 - 0.2 11.9 1.1 0.89 9.8 1.1 2.0 1 1 0 1 1 1 0 AAA domain DUF898 PF05987.13 KKF97568.1 - 0.044 12.8 5.7 0.085 11.9 5.7 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF1688 PF07958.11 KKF97569.1 - 7.2e-155 515.8 0.0 8.3e-155 515.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Herpes_capsid PF06112.11 KKF97569.1 - 1.7 8.7 7.5 3.4 7.7 7.5 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein 60KD_IMP PF02096.20 KKF97570.1 - 1.7e-16 60.5 3.0 4.9e-16 59.1 3.0 1.7 1 1 0 1 1 1 1 60Kd inner membrane protein TOM13 PF08219.11 KKF97571.1 - 1.7e-34 117.6 0.0 2.1e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 Gtr1_RagA PF04670.12 KKF97572.1 - 1.7e-91 305.7 0.0 2.1e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KKF97572.1 - 1e-08 35.4 0.0 2.9e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKF97572.1 - 1.1e-08 34.8 0.1 2.9e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 KKF97572.1 - 7.2e-08 32.5 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KKF97572.1 - 8.1e-08 31.9 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KKF97572.1 - 0.00015 21.1 2.0 0.24 10.5 0.5 2.9 2 1 1 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 KKF97572.1 - 0.0036 17.0 0.9 0.05 13.4 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KKF97572.1 - 0.007 16.9 0.2 0.017 15.6 0.2 1.6 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KKF97572.1 - 0.014 15.3 0.3 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 KKF97572.1 - 0.015 14.5 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SCO1-SenC PF02630.14 KKF97572.1 - 0.084 12.8 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 SCO1/SenC SEP PF08059.13 KKF97573.1 - 3.3e-20 72.4 0.0 8.9e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KKF97573.1 - 7e-08 32.6 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KKF97573.1 - 2e-07 30.7 0.0 3.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KKF97573.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain Bromodomain PF00439.25 KKF97574.1 - 1.3e-27 95.6 0.0 4e-19 68.4 0.0 3.0 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 KKF97574.1 - 4.3e-14 52.4 1.3 9.4e-14 51.3 1.3 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF2828 PF11443.8 KKF97575.1 - 0.001 17.3 14.3 0.0014 16.8 14.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Vfa1 PF08432.10 KKF97575.1 - 0.88 9.9 29.3 1.8 8.9 29.3 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.8 KKF97575.1 - 1.1 8.0 25.8 1.6 7.5 25.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 KKF97575.1 - 1.2 9.0 25.2 1.9 8.3 25.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ArAE_2_N PF10337.9 KKF97575.1 - 2.1 7.3 7.6 3.4 6.6 7.6 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal V_ATPase_I PF01496.19 KKF97575.1 - 4 5.2 11.5 7 4.4 11.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2052 PF09747.9 KKF97575.1 - 5.2 7.2 24.8 10 6.2 24.8 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 KKF97575.1 - 5.4 6.7 14.1 12 5.5 14.1 1.7 1 0 0 1 1 1 0 FAM176 family AAA_11 PF13086.6 KKF97575.1 - 6.6 6.4 17.5 12 5.6 17.5 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_S64 PF08192.11 KKF97575.1 - 7.1 5.0 16.7 9.1 4.6 16.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 SOBP PF15279.6 KKF97575.1 - 7.7 7.0 11.1 13 6.3 11.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DDE_Tnp_IS1595 PF12762.7 KKF97575.1 - 8 6.5 13.3 49 3.9 13.3 2.2 1 1 0 1 1 1 0 ISXO2-like transposase domain WD40 PF00400.32 KKF97576.1 - 9.7e-08 32.6 3.0 0.0094 16.8 0.0 3.0 2 1 1 3 3 3 2 WD domain, G-beta repeat BAR_2 PF10455.9 KKF97577.1 - 1e-58 198.8 0.3 1.8e-58 198.0 0.3 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KKF97577.1 - 3e-24 86.0 2.7 3.2e-23 82.6 2.7 2.2 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KKF97577.1 - 0.0055 16.4 0.4 0.019 14.7 0.1 2.1 2 0 0 2 2 2 1 BAR domain of APPL family RNA_pol_I_TF PF04090.12 KKF97577.1 - 0.024 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor ETC_C1_NDUFA5 PF04716.14 KKF97578.1 - 6.8e-25 86.7 3.5 8e-23 80.0 0.1 3.0 3 0 0 3 3 3 2 ETC complex I subunit conserved region QLQ PF08880.11 KKF97578.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 QLQ Phage_TAC_11 PF11836.8 KKF97578.1 - 0.097 12.8 0.3 0.35 11.0 0.2 1.9 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 NAT PF04768.13 KKF97579.1 - 4.1e-49 166.5 0.0 5.1e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase NAD_binding_2 PF03446.15 KKF97580.1 - 7.6e-27 94.4 0.1 1.3e-26 93.7 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KKF97580.1 - 8.8e-11 42.1 0.4 1.7e-10 41.2 0.4 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KKF97580.1 - 1.9e-06 28.0 0.0 5.4e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KKF97580.1 - 1.1e-05 26.0 0.8 4.1e-05 24.1 0.0 2.5 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KKF97580.1 - 0.002 18.4 0.0 0.0048 17.2 0.0 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KKF97580.1 - 0.032 14.1 0.6 0.057 13.3 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H-binding ATP_synt_H PF05493.13 KKF97581.1 - 1.7e-23 82.8 3.6 2e-23 82.6 3.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit H DUF2232 PF09991.9 KKF97581.1 - 0.032 13.4 3.3 0.036 13.2 3.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) MtrC PF04211.13 KKF97581.1 - 0.038 13.1 0.4 0.04 13.0 0.4 1.0 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C VIT1 PF01988.19 KKF97581.1 - 0.32 10.8 3.5 0.34 10.8 3.5 1.0 1 0 0 1 1 1 0 VIT family OppC_N PF12911.7 KKF97581.1 - 0.49 10.4 9.5 4.1 7.4 0.6 2.1 1 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3784 PF12650.7 KKF97581.1 - 0.57 10.4 5.2 0.72 10.1 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) Popeye PF04831.13 KKF97581.1 - 0.63 10.2 2.7 0.76 9.9 2.7 1.1 1 0 0 1 1 1 0 Popeye protein conserved region Arv1 PF04161.13 KKF97582.1 - 1.9e-72 243.9 1.7 2.2e-72 243.6 1.7 1.1 1 0 0 1 1 1 1 Arv1-like family LysM PF01476.20 KKF97583.1 - 0.047 13.8 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 LysM domain Fungal_trans PF04082.18 KKF97584.1 - 2.2e-37 128.5 0.0 4.8e-37 127.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain PigN PF04987.14 KKF97585.1 - 4e-162 540.2 34.1 4e-162 540.2 34.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KKF97585.1 - 1.3e-09 38.2 5.1 5.5e-08 32.8 5.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKF97585.1 - 6.6e-09 35.6 0.1 9.9e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KKF97585.1 - 0.0001 21.7 0.1 0.00019 20.9 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Csm1 PF12539.8 KKF97586.1 - 4.4e-34 117.0 0.0 8.9e-34 116.0 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Rootletin PF15035.6 KKF97586.1 - 0.28 11.2 11.0 0.12 12.3 8.4 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF5094 PF17015.5 KKF97586.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF5094) AAA_13 PF13166.6 KKF97586.1 - 7.1 5.1 8.8 0.13 10.8 1.7 1.6 2 0 0 2 2 2 0 AAA domain DUF2420 PF10336.9 KKF97587.1 - 1.3e-08 34.8 0.2 2.6e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 KKF97588.1 - 9.4e-20 71.1 0.4 1.3e-19 70.6 0.4 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KKF97588.1 - 1e-05 25.5 0.2 1.9e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 KKF97588.1 - 0.00049 20.5 0.2 0.001 19.5 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) LptF_LptG PF03739.14 KKF97588.1 - 0.16 10.8 0.1 0.41 9.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Questin_oxidase PF14027.6 KKF97589.1 - 0.12 11.9 0.9 0.33 10.5 0.8 1.7 1 1 0 1 1 1 0 Questin oxidase-like DUF3886 PF13025.6 KKF97589.1 - 0.14 12.3 4.3 0.35 11.1 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) NEMO PF11577.8 KKF97589.1 - 0.8 9.8 6.3 1.7 8.7 6.3 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Peptidase_S10 PF00450.22 KKF97590.1 - 2e-58 198.8 0.0 4.5e-58 197.6 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase zf-Nse PF11789.8 KKF97591.1 - 1.2e-17 63.5 0.1 2.1e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KKF97591.1 - 0.00018 21.4 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKF97591.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) V_ATPase_I PF01496.19 KKF97591.1 - 0.092 10.6 2.1 0.13 10.2 2.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM237 PF15383.6 KKF97591.1 - 0.16 11.0 0.1 0.32 10.1 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 zf-MIZ PF02891.20 KKF97591.1 - 0.21 11.4 0.1 0.4 10.5 0.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RXT2_N PF08595.11 KKF97591.1 - 1.6 8.7 11.0 0.99 9.4 0.3 3.0 3 0 0 3 3 3 0 RXT2-like, N-terminal PH PF00169.29 KKF97592.1 - 0.0013 19.2 0.0 0.0023 18.4 0.0 1.4 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.18 KKF97592.1 - 0.07 13.0 0.7 0.18 11.7 0.7 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain KH_2 PF07650.17 KKF97592.1 - 1.3 8.9 4.3 6.5 6.7 2.0 2.7 2 1 1 3 3 3 0 KH domain Arrestin_C PF02752.22 KKF97593.1 - 3e-13 50.4 0.2 6.3e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KKF97593.1 - 6.7e-12 45.7 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KKF97593.1 - 0.00098 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like EF_assoc_1 PF08355.12 KKF97594.1 - 6.3e-27 93.0 0.3 1.3e-26 92.0 0.2 1.6 2 0 0 2 2 2 1 EF hand associated EF_assoc_2 PF08356.12 KKF97594.1 - 7.8e-22 77.1 0.0 1e-20 73.5 0.0 2.3 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 KKF97594.1 - 5.3e-05 22.9 0.0 7.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.6 KKF97594.1 - 0.0015 18.9 0.0 0.0023 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KKF97594.1 - 0.0019 17.9 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KKF97594.1 - 0.006 16.9 0.0 0.01 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KKF97594.1 - 0.023 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ploopntkinase3 PF18751.1 KKF97594.1 - 0.07 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Roc PF08477.13 KKF97594.1 - 0.18 12.0 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KKF97594.1 - 0.22 11.1 0.2 0.22 11.1 0.2 1.9 2 0 0 2 2 2 0 EF hand Pox_MCEL PF03291.16 KKF97595.1 - 2.7e-76 256.8 0.0 1.4e-51 175.6 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KKF97595.1 - 3.3e-10 40.5 0.0 2.8e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKF97595.1 - 2.1e-09 38.0 0.2 1.9e-08 35.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKF97595.1 - 9.6e-07 28.8 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKF97595.1 - 1.1e-05 25.3 0.0 5.5e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKF97595.1 - 1.6e-05 25.5 0.0 8e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KKF97595.1 - 0.002 17.4 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Raftlin PF15250.6 KKF97595.1 - 0.081 11.7 5.8 0.092 11.5 0.0 2.1 2 0 0 2 2 2 0 Raftlin FAM92 PF06730.11 KKF97595.1 - 0.62 9.4 3.5 1.1 8.6 3.5 1.3 1 0 0 1 1 1 0 FAM92 protein DUF2058 PF09831.9 KKF97595.1 - 0.95 9.6 7.6 2.2 8.4 7.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF3915 PF13054.6 KKF97595.1 - 3.7 7.6 6.4 9.4 6.2 6.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) RPN7 PF10602.9 KKF97596.1 - 2e-52 177.4 1.4 2.5e-52 177.1 0.3 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KKF97596.1 - 1.5e-15 57.6 0.0 3.8e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain Hpre_diP_synt_I PF07456.11 KKF97596.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase component I TPR_14 PF13428.6 KKF97596.1 - 0.17 12.8 0.9 0.63 11.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKF97596.1 - 0.18 12.5 2.0 1.4 9.7 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 KKF97597.1 - 1.3e-36 126.6 0.0 1.8e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KKF97597.1 - 0.049 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase NDT80_PhoG PF05224.12 KKF97598.1 - 1.3e-44 152.7 0.6 3.4e-44 151.3 0.1 1.8 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Adeno_PIX PF03955.14 KKF97598.1 - 0.071 13.3 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Bromodomain PF00439.25 KKF97599.1 - 4.4e-19 68.3 0.0 6.2e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Bromodomain Ykof PF07615.11 KKF97599.1 - 0.18 12.3 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 YKOF-related Family Mlh1_C PF16413.5 KKF97600.1 - 4.5e-98 327.9 0.0 5.2e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus BUD22 PF09073.10 KKF97602.1 - 0.27 10.5 3.4 0.51 9.6 3.4 1.5 1 0 0 1 1 1 0 BUD22 DnaJ PF00226.31 KKF97603.1 - 4.6e-14 52.3 0.3 4.6e-14 52.3 0.3 2.3 2 1 1 3 3 3 1 DnaJ domain Izumo-Ig PF16706.5 KKF97603.1 - 0.043 13.9 0.1 0.075 13.1 0.1 1.3 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain DEAD PF00270.29 KKF97604.1 - 2.4e-49 167.5 0.1 1.1e-48 165.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKF97604.1 - 1.9e-24 86.2 0.0 1.6e-23 83.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KKF97604.1 - 3.5e-22 78.4 1.6 3.5e-22 78.4 1.6 2.2 2 0 0 2 2 2 1 DBP10CT (NUC160) domain IML1 PF12257.8 KKF97605.1 - 8.3e-98 327.0 0.0 1.2e-97 326.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KKF97605.1 - 4.9e-12 45.7 1.3 8.9e-12 44.9 0.1 2.2 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NOPS PF08075.11 KKF97606.1 - 0.093 12.9 0.0 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 NOPS (NUC059) domain Nipped-B_C PF12830.7 KKF97607.1 - 1.3e-46 158.9 5.3 1.4e-45 155.6 2.3 3.0 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KKF97607.1 - 9.3e-09 35.4 0.5 1.1e-06 28.8 0.1 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KKF97607.1 - 8e-06 25.7 0.1 0.057 13.7 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KKF97607.1 - 0.0036 17.4 0.3 0.13 12.3 0.0 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 TFIIS_C PF01096.18 KKF97608.1 - 6.2e-15 54.8 4.1 1.8e-14 53.3 1.1 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) ArfGap PF01412.18 KKF97608.1 - 0.028 14.5 0.9 0.76 9.9 0.2 2.2 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf RNA_POL_M_15KD PF02150.16 KKF97608.1 - 0.051 13.4 4.0 0.42 10.5 0.1 2.6 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit UCH_1 PF13423.6 KKF97608.1 - 0.057 13.0 1.1 0.077 12.6 1.1 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Baculo_LEF5_C PF11792.8 KKF97608.1 - 0.087 12.5 3.6 1.6 8.5 0.1 2.9 2 1 1 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain HEAT_2 PF13646.6 KKF97609.1 - 3.8e-27 94.5 2.9 1.3e-11 44.7 0.1 3.5 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 KKF97609.1 - 1e-18 66.0 2.5 0.032 14.9 0.0 6.0 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KKF97609.1 - 1.4e-08 34.3 2.2 0.063 13.6 0.1 5.3 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 KKF97609.1 - 0.00074 19.5 3.3 0.11 12.5 0.0 3.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKF97609.1 - 0.00083 19.8 7.1 5.4 7.6 0.4 5.1 3 2 2 5 5 5 2 HEAT-like repeat RuvA_C PF07499.13 KKF97609.1 - 0.28 11.7 5.1 7 7.2 0.2 3.6 3 0 0 3 3 3 0 RuvA, C-terminal domain ParA PF10609.9 KKF97610.1 - 1e-93 313.4 0.0 1.2e-93 313.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KKF97610.1 - 4.1e-08 33.3 0.0 1.1e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KKF97610.1 - 0.00018 21.5 0.0 0.00065 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KKF97610.1 - 0.00073 18.8 0.0 0.0032 16.7 0.1 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KKF97610.1 - 0.0021 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KKF97610.1 - 0.0099 15.4 0.0 0.91 8.9 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 KKF97610.1 - 0.014 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KKF97610.1 - 0.027 14.9 0.0 0.044 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_26 PF13500.6 KKF97610.1 - 0.027 14.3 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KKF97610.1 - 0.053 13.4 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain MipZ PF09140.11 KKF97610.1 - 0.059 12.6 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ T2SSE PF00437.20 KKF97610.1 - 0.084 11.9 0.1 0.82 8.7 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein CLP1_P PF16575.5 KKF97610.1 - 0.086 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 KKF97610.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KKF97610.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 KKF97610.1 - 0.16 12.0 0.2 1.5 8.9 0.2 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KKF97610.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MoCF_biosynth PF00994.24 KKF97611.1 - 1.2e-21 76.9 0.0 3.6e-21 75.3 0.0 1.6 1 1 1 2 2 2 1 Probable molybdopterin binding domain Ras PF00071.22 KKF97612.1 - 3.4e-59 199.1 0.2 4e-59 198.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKF97612.1 - 2.3e-20 73.0 0.0 3.1e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKF97612.1 - 5.2e-08 32.5 0.0 6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKF97612.1 - 1.1e-05 25.1 0.2 7.7e-05 22.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKF97612.1 - 0.00034 20.6 0.6 0.96 9.3 0.1 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKF97612.1 - 0.0021 18.1 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KKF97612.1 - 0.007 16.4 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 KKF97612.1 - 0.061 13.1 2.0 0.49 10.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KKF97613.1 - 1.5e-20 73.9 0.0 1.6e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Dynamin family JAB PF01398.21 KKF97613.1 - 0.16 12.0 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PIG-F PF06699.11 KKF97616.1 - 8.1e-59 198.8 4.0 9.7e-59 198.6 4.0 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2070 PF09843.9 KKF97616.1 - 2.9 6.1 5.5 4.6 5.4 5.5 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Abhydrolase_1 PF00561.20 KKF97617.1 - 5.2e-19 68.9 0.0 1.5e-16 60.9 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKF97617.1 - 5.3e-16 59.9 0.5 2.4e-15 57.7 0.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKF97617.1 - 1.1e-11 44.5 0.0 2.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SRPRB PF09439.10 KKF97618.1 - 7.9e-28 97.1 0.0 2.4e-27 95.5 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKF97618.1 - 3.7e-06 27.0 0.0 6.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KKF97618.1 - 4e-05 23.1 0.0 0.005 16.3 0.0 2.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKF97618.1 - 0.00056 19.5 0.1 0.15 11.6 0.1 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 KKF97618.1 - 0.023 14.9 0.0 0.061 13.5 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKF97618.1 - 0.026 14.1 0.0 0.32 10.6 0.0 2.5 2 1 0 2 2 2 0 Ras family TniB PF05621.11 KKF97618.1 - 0.035 13.5 0.0 0.26 10.7 0.0 2.0 1 1 1 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 KKF97618.1 - 0.038 13.5 0.2 1.9 8.0 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B IstB_IS21 PF01695.17 KKF97618.1 - 0.058 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein cobW PF02492.19 KKF97618.1 - 0.12 12.0 0.0 17 5.0 0.0 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Spo7 PF03907.13 KKF97619.1 - 2.9e-93 311.4 0.0 4.1e-93 310.9 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein DUF565 PF04483.12 KKF97619.1 - 0.0057 17.2 0.5 8.1 7.1 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF565) AAA PF00004.29 KKF97620.1 - 3.2e-10 40.5 0.0 7.3e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKF97620.1 - 5.4e-05 23.2 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KKF97620.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KKF97620.1 - 0.00022 21.2 0.0 0.00094 19.1 0.0 2.0 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KKF97620.1 - 0.00033 20.9 0.0 0.00094 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKF97620.1 - 0.0025 18.0 0.0 0.0071 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKF97620.1 - 0.0026 18.1 0.5 0.024 15.0 0.0 2.6 3 1 0 4 4 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKF97620.1 - 0.0061 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 KKF97620.1 - 0.011 15.4 0.7 0.031 14.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKF97620.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKF97620.1 - 0.037 13.9 0.1 0.082 12.8 0.1 1.6 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KKF97620.1 - 0.056 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KKF97620.1 - 0.085 13.4 0.0 0.31 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKF97620.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KKF97620.1 - 0.2 12.0 0.9 1.9 8.8 0.2 2.7 2 1 0 2 2 2 0 AAA domain Ferrochelatase PF00762.19 KKF97621.1 - 9.6e-96 320.6 0.0 1.1e-95 320.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.16 KKF97622.1 - 1.9e-43 148.6 0.0 5.6e-43 147.0 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KKF97622.1 - 1.2e-34 119.9 0.0 1.8e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KKF97622.1 - 2.7e-22 79.2 0.4 8.3e-22 77.7 0.1 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KKF97622.1 - 3.3e-10 39.5 0.0 5.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KKF97622.1 - 0.03 14.0 0.1 0.03 14.0 0.1 2.2 2 0 0 2 2 2 0 HeH/LEM domain LETM1 PF07766.13 KKF97622.1 - 0.055 12.8 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 LETM1-like protein PPR_3 PF13812.6 KKF97623.1 - 2e-09 37.4 0.6 0.0011 19.0 0.0 3.9 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 KKF97623.1 - 4.5e-07 29.7 1.4 2.2 8.7 0.0 6.6 7 0 0 7 7 7 1 PPR repeat PPR_long PF17177.4 KKF97623.1 - 7.4e-05 22.2 0.0 0.0017 17.8 0.0 2.8 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 KKF97623.1 - 0.0032 17.6 2.4 6.6 7.0 0.0 4.7 6 1 1 7 7 7 2 PPR repeat family TPR_14 PF13428.6 KKF97623.1 - 0.022 15.6 0.1 5.7 8.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKF97623.1 - 0.063 13.3 0.1 0.6 10.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKF97623.1 - 0.092 12.9 0.3 0.46 10.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_1 PF12854.7 KKF97623.1 - 1.2 8.9 3.2 16 5.3 0.0 3.4 4 0 0 4 4 4 0 PPR repeat TRM PF02005.16 KKF97625.1 - 4.1e-106 355.3 0.0 3.4e-104 349.0 0.0 2.1 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KKF97625.1 - 0.0015 18.4 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DAGK_cat PF00781.24 KKF97626.1 - 8.8e-13 48.0 0.0 1.6e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RIO1 PF01163.22 KKF97627.1 - 1.2e-41 142.4 0.0 3.4e-40 137.7 0.0 2.1 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KKF97627.1 - 1.6e-29 101.9 0.2 3.6e-29 100.8 0.1 1.7 2 0 0 2 2 1 1 Rio2, N-terminal APH PF01636.23 KKF97627.1 - 3.7e-08 33.6 0.1 0.0005 20.1 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KKF97627.1 - 3.3e-06 26.6 0.0 0.005 16.2 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family PaaX PF07848.12 KKF97627.1 - 0.055 13.7 0.4 0.15 12.3 0.2 1.8 2 0 0 2 2 2 0 PaaX-like protein RPN2_C PF18004.1 KKF97627.1 - 0.18 11.7 2.8 0.29 11.0 2.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Trypan_PARP PF05887.11 KKF97627.1 - 0.59 10.1 14.1 1.3 9.0 14.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Merozoite_SPAM PF07133.11 KKF97627.1 - 1.8 8.5 22.8 3.2 7.7 22.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) NOA36 PF06524.12 KKF97627.1 - 3.2 7.0 15.3 4.8 6.4 15.3 1.1 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 KKF97627.1 - 4.9 6.6 13.9 7.1 6.1 13.9 1.2 1 0 0 1 1 1 0 PPP4R2 CobT PF06213.12 KKF97627.1 - 7.6 5.8 17.8 13 5.1 17.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 KKF97627.1 - 9.9 4.2 18.9 13 3.8 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family RPN1_RPN2_N PF17781.1 KKF97628.1 - 5.9e-109 364.2 3.4 8.7e-109 363.6 3.4 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KKF97628.1 - 1.7e-25 88.8 0.1 3.3e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KKF97628.1 - 8.6e-19 67.0 18.9 7.4e-08 32.4 0.6 8.9 8 0 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KKF97628.1 - 1.2e-07 32.0 1.6 0.00035 20.9 0.0 4.0 5 0 0 5 5 5 2 HEAT repeats MTHFR PF02219.17 KKF97630.1 - 3.5e-115 384.3 0.0 4.7e-115 383.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TcA_TcB_BD PF18276.1 KKF97630.1 - 0.2 10.7 0.0 0.39 9.7 0.0 1.4 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain HTH_Tnp_Tc5 PF03221.16 KKF97631.1 - 6.5e-18 64.5 1.2 7.8e-07 29.0 0.1 5.0 5 0 0 5 5 5 4 Tc5 transposase DNA-binding domain zf-met PF12874.7 KKF97631.1 - 0.42 11.1 2.6 87 3.7 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type TTSSLRR PF12468.8 KKF97633.1 - 0.79 10.0 0.0 0.79 10.0 0.0 3.3 3 0 0 3 3 3 0 Type III secretion system leucine rich repeat protein CCDC158 PF15921.5 KKF97633.1 - 6.3 4.5 12.8 11 3.7 12.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 RRM_1 PF00076.22 KKF97634.1 - 5.5e-08 32.5 0.4 1.8e-06 27.7 0.2 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKF97634.1 - 5.7e-06 26.2 0.0 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KKF97634.1 - 8e-05 22.6 4.4 0.027 14.5 1.2 3.4 2 1 1 3 3 3 2 RNA binding motif RRM_occluded PF16842.5 KKF97634.1 - 0.00053 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KKF97634.1 - 0.0072 16.6 1.3 0.15 12.3 0.0 2.5 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter AAA_23 PF13476.6 KKF97634.1 - 0.053 14.0 5.2 0.088 13.3 5.2 1.5 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 KKF97634.1 - 0.35 9.9 4.5 0.54 9.3 4.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 KKF97634.1 - 2.5 8.7 10.9 5 7.8 10.9 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NAM-associated PF14303.6 KKF97634.1 - 4.9 7.8 12.8 4.2 8.0 7.8 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain GTP_EFTU PF00009.27 KKF97635.1 - 7.1e-65 218.2 0.2 1.1e-64 217.6 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KKF97635.1 - 1.5e-31 108.7 0.0 6.2e-31 106.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KKF97635.1 - 1.1e-22 79.8 0.0 3.9e-22 78.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 KKF97635.1 - 2e-12 47.0 0.0 6.4e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KKF97635.1 - 1.1e-11 44.9 0.1 4e-11 43.1 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKF97635.1 - 3.3e-05 23.9 1.4 4.5e-05 23.5 0.3 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KKF97635.1 - 0.0031 17.3 0.1 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Solute_trans_a PF03619.16 KKF97636.1 - 8.6e-82 274.6 6.0 8.6e-82 274.6 6.0 1.6 1 1 1 2 2 2 1 Organic solute transporter Ostalpha PI3K_1B_p101 PF10486.9 KKF97636.1 - 0.034 12.0 0.1 0.045 11.5 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SPATA3 PF15662.5 KKF97636.1 - 0.5 11.0 7.2 0.91 10.1 7.2 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Herpes_pp85 PF04637.12 KKF97636.1 - 4 5.7 6.9 5.8 5.2 6.9 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Sec5 PF15469.6 KKF97639.1 - 2e-38 132.1 0.0 7.3e-38 130.3 0.0 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec5 Clathrin_bdg PF15045.6 KKF97639.1 - 0.031 14.3 0.0 2.2 8.4 0.0 2.7 1 1 1 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking LRR_9 PF14580.6 KKF97640.1 - 2.9e-55 186.5 0.2 4.4e-55 185.9 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KKF97640.1 - 2.5e-09 36.8 1.4 2.5e-09 36.8 1.4 2.2 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 KKF97640.1 - 1e-06 28.9 10.9 5.5e-06 26.6 0.8 3.7 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) PspB PF06667.12 KKF97640.1 - 0.088 12.9 1.8 0.21 11.7 1.8 1.6 1 0 0 1 1 1 0 Phage shock protein B T4_Gp59_C PF08994.10 KKF97640.1 - 0.092 13.4 0.1 0.21 12.2 0.0 1.6 2 0 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase C-term SpoIIIAH PF12685.7 KKF97640.1 - 0.11 12.3 0.6 0.15 11.8 0.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein LRR_6 PF13516.6 KKF97640.1 - 0.43 10.8 6.1 25 5.2 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat CBFD_NFYB_HMF PF00808.23 KKF97641.1 - 2.4e-11 43.7 0.2 4.2e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CBS PF00571.28 KKF97642.1 - 2.8e-10 40.5 0.1 0.00032 21.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain Voltage_CLC PF00654.20 KKF97642.1 - 7.4e-10 38.6 8.8 4.5e-06 26.1 0.4 2.7 2 1 1 3 3 3 2 Voltage gated chloride channel DUF5353 PF17304.2 KKF97642.1 - 0.44 10.3 4.4 0.53 10.1 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5353) ATP-synt_C PF00137.21 KKF97643.1 - 6.2e-27 93.7 25.7 3.7e-15 56.0 11.6 2.4 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 KKF97643.1 - 0.013 14.9 1.1 0.09 12.1 0.1 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 MIG-14_Wnt-bd PF06664.12 KKF97643.1 - 2.2 7.4 6.6 0.48 9.6 2.1 2.0 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion ATP_bind_1 PF03029.17 KKF97644.1 - 1.3e-54 185.5 0.1 7.9e-39 133.9 0.0 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Muted PF14942.6 KKF97644.1 - 0.022 15.1 0.1 0.041 14.2 0.1 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Pyridoxal_deC PF00282.19 KKF97645.1 - 2e-97 326.3 0.0 1.2e-96 323.7 0.0 2.0 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain AA_permease_2 PF13520.6 KKF97645.1 - 5e-31 108.0 28.1 5e-31 108.0 28.1 2.0 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 KKF97645.1 - 2.4e-16 59.4 26.0 2.4e-16 59.4 26.0 1.8 1 1 1 2 2 2 2 Amino acid permease Transp_cyt_pur PF02133.15 KKF97646.1 - 2.6e-97 326.4 42.6 2.9e-97 326.2 42.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Ceratocystis_platani-ASM97888v1/GCA_000978885.1_ASM97888v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Ceratocystis_platani-ASM97888v1/GCA_000978885.1_ASM97888v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Ceratocystis_platani-ASM97888v1/GCA_000978885.1_ASM97888v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Ceratocystis_platani-ASM97888v1/GCA_000978885.1_ASM97888v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 15:59:59 2019 # [ok]