# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Metallothio_Euk PF12749.7 CEG19311.1 - 0.1 12.8 6.3 0.18 12.0 6.3 1.3 1 0 0 1 1 1 0 Eukaryotic metallothionein zf-C3HC4_3 PF13920.6 CEG19311.1 - 0.4 10.6 7.5 0.67 9.9 7.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PSI_integrin PF17205.3 CEG19311.1 - 0.49 10.2 11.1 4.8 7.0 3.3 2.3 1 1 1 2 2 2 0 Integrin plexin domain UL42 PF17638.2 CEG19321.1 - 0.16 11.9 0.0 0.18 11.8 0.0 1.0 1 0 0 1 1 1 0 HCMV UL42 Acetyltransf_1 PF00583.25 CEG19324.1 - 0.013 15.7 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEG19324.1 - 0.019 14.9 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEG19324.1 - 0.038 14.0 0.0 0.043 13.8 0.0 1.1 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 CEG19324.1 - 0.054 13.6 0.1 0.082 13.0 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1263 PF06882.12 CEG19326.1 - 0.14 12.2 0.1 0.2 11.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1263) DUF16 PF01519.16 CEG19327.1 - 0.11 13.0 2.8 0.17 12.4 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Prenylcys_lyase PF07156.14 CEG19332.1 - 0.017 14.2 0.0 0.017 14.2 0.0 1.0 1 0 0 1 1 1 0 Prenylcysteine lyase Rieske PF00355.26 CEG19335.1 - 0.024 14.6 0.0 0.029 14.3 0.0 1.3 1 1 0 1 1 1 0 Rieske [2Fe-2S] domain rve_3 PF13683.6 CEG19335.1 - 0.15 11.8 0.0 0.18 11.6 0.0 1.3 1 1 0 1 1 1 0 Integrase core domain Clat_adaptor_s PF01217.20 CEG19336.1 - 4.6e-15 55.8 0.0 1e-07 32.0 0.0 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain CDC37_N PF03234.14 CEG19340.1 - 3.9e-32 111.9 0.6 4.4e-32 111.7 0.6 1.0 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding DFRP_C PF16543.5 CEG19340.1 - 0.019 15.4 1.5 0.019 15.4 1.5 1.4 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 PS_Dcarbxylase PF02666.15 CEG19341.1 - 6.3e-18 65.0 0.0 7.1e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF3074 PF11274.8 CEG19342.1 - 9.7e-07 28.9 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) PAH PF02671.21 CEG19347.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Paired amphipathic helix repeat DUF3072 PF11272.8 CEG19348.1 - 0.06 13.3 0.7 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) DUF659 PF04937.15 CEG19350.1 - 2.7e-05 24.1 0.0 7.6e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CTP_transf_1 PF01148.20 CEG19352.1 - 3.3e-26 92.6 0.1 3.8e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF4250 PF14056.6 CEG19355.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) gpD PF02925.16 CEG19358.1 - 2e-98 326.0 1.7 2.3e-98 325.8 1.7 1.0 1 0 0 1 1 1 1 Bacteriophage scaffolding protein D Microvir_H PF04687.12 CEG19359.1 - 6.6e-217 718.8 22.3 7.5e-217 718.7 22.3 1.0 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) RVT_1 PF00078.27 CEG19362.1 - 1.6e-11 44.2 0.2 1.2e-10 41.3 0.2 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyl-CoA_dh_1 PF00441.24 CEG19367.1 - 3.6e-28 98.7 0.1 3.9e-28 98.5 0.1 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 CEG19367.1 - 5.7e-08 33.1 0.0 6.3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain EMP24_GP25L PF01105.24 CEG19368.1 - 5.1e-25 88.5 0.1 5.6e-25 88.3 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SpvB PF03534.13 CEG19372.1 - 0.075 12.2 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein Ribosomal_L32e PF01655.18 CEG19375.1 - 0.00016 22.1 0.1 0.00023 21.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L32 Proton_antipo_M PF00361.20 CEG19376.1 - 2.2e-31 109.2 13.6 3.4e-31 108.5 13.6 1.3 1 0 0 1 1 1 1 Proton-conducting membrane transporter Cytochrom_B_C PF00032.17 CEG19377.1 - 4.7e-11 42.9 0.5 9.4e-11 41.9 0.5 1.5 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD DUF2254 PF10011.9 CEG19377.1 - 0.0037 16.1 0.3 0.0041 16.0 0.3 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) MotB_plug PF13677.6 CEG19377.1 - 0.088 12.4 0.2 0.17 11.5 0.2 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Proton_antipo_M PF00361.20 CEG19378.1 - 9.7e-62 208.8 18.5 9.7e-62 208.8 18.5 3.0 3 0 0 3 3 3 1 Proton-conducting membrane transporter NADH5_C PF06455.11 CEG19378.1 - 2.3e-10 40.4 23.0 2.3e-10 40.3 15.4 3.1 2 1 0 2 2 2 1 NADH dehydrogenase subunit 5 C-terminus COX1 PF00115.20 CEG19379.1 - 3e-86 290.0 38.0 3.3e-86 289.8 38.0 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I ATP-synt_A PF00119.20 CEG19380.1 - 1.9e-41 142.4 24.8 2.3e-41 142.1 24.8 1.1 1 0 0 1 1 1 1 ATP synthase A chain COX3 PF00510.18 CEG19381.1 - 2.4e-114 381.6 22.4 2.7e-114 381.4 22.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III DUF1129 PF06570.11 CEG19381.1 - 0.84 9.1 7.1 6 6.3 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) GIY-YIG PF01541.24 CEG19382.1 - 0.00081 19.6 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-CCHC_3 PF13917.6 CEH11663.1 - 7.6e-15 54.6 0.5 1.2e-14 54.0 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF2382 PF09557.10 CEH11664.1 - 0.087 13.1 0.2 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2382) MMR_HSR1 PF01926.23 CEH11670.1 - 8.1e-06 25.9 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2974 PF11187.8 CEH11670.1 - 0.00012 21.7 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CEH11670.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) ABC_tran PF00005.27 CEH11670.1 - 0.0049 17.4 0.0 0.016 15.8 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Abhydrolase_6 PF12697.7 CEH11670.1 - 0.0056 17.3 1.2 0.0056 17.3 1.2 2.8 2 2 0 2 2 2 1 Alpha/beta hydrolase family Septin PF00735.18 CEH11670.1 - 0.013 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 CEH11670.1 - 0.018 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 CEH11670.1 - 0.08 13.2 0.0 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF676 PF05057.14 CEH11670.1 - 0.083 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Roc PF08477.13 CEH11670.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CEH11670.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase PPP1R35_C PF15503.6 CEH11671.1 - 0.0078 16.0 2.6 0.02 14.7 2.6 1.6 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus Caerin_1 PF07440.12 CEH11671.1 - 0.0082 16.2 0.2 0.023 14.8 0.2 1.8 1 0 0 1 1 1 1 Caerin 1 protein Dicer_N PF17895.1 CEH11671.1 - 0.99 9.2 0.0 0.99 9.2 0.0 2.7 3 1 1 4 4 4 0 Giardia Dicer N-terminal domain Protamine_P2 PF00841.19 CEH11671.1 - 2.1 8.9 9.0 3.2 8.3 0.5 2.9 2 0 0 2 2 2 0 Sperm histone P2 PTPA PF03095.15 CEH11672.1 - 2e-89 300.1 0.0 2.4e-89 299.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MAT1 PF06391.13 CEH11673.1 - 5.6e-22 78.6 6.3 8.3e-22 78.0 6.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 CEH11673.1 - 1.8e-08 34.1 0.4 3e-08 33.4 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) YqfD PF06898.11 CEH11673.1 - 0.12 11.2 0.8 0.16 10.8 0.8 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD EI24 PF07264.11 CEH11674.1 - 4.1e-27 95.5 12.6 6.1e-27 95.0 12.6 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) JAB PF01398.21 CEH11675.1 - 8.2e-21 74.2 0.0 2.3e-20 72.7 0.0 1.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CEH11675.1 - 1.9e-15 57.3 0.2 4.2e-15 56.2 0.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Ribosomal_L19 PF01245.20 CEH11676.1 - 9.6e-17 60.9 1.7 1.1e-16 60.8 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L19 Spt20 PF12090.8 CEH11676.1 - 0.44 10.1 7.0 0.69 9.5 7.0 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CEH11676.1 - 1.3 9.2 12.8 0.11 12.6 5.5 2.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 EBP50_C PF09007.11 CEH11676.1 - 2.5 9.1 8.3 0.4 11.7 4.0 2.0 2 0 0 2 2 2 0 EBP50, C-terminal DUF1635 PF07795.11 CEH11676.1 - 3.8 7.3 8.0 0.26 11.1 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Ribosomal_L6 PF00347.23 CEH11677.1 - 2.6e-21 76.1 1.3 3.2e-12 46.9 0.3 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 polyprenyl_synt PF00348.17 CEH11678.1 - 3.5e-46 157.4 0.2 2.8e-29 101.9 0.0 3.4 1 1 2 3 3 3 3 Polyprenyl synthetase Methyltransf_23 PF13489.6 CEH11679.1 - 3.2e-06 27.1 0.0 5.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH11679.1 - 7e-05 23.4 0.1 0.033 14.8 0.0 2.8 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH11679.1 - 9.4e-05 23.0 0.1 0.16 12.7 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CEH11679.1 - 0.00013 22.7 0.1 0.0024 18.6 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH11679.1 - 0.0029 17.4 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain MetW PF07021.12 CEH11679.1 - 0.093 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 CEH11679.1 - 0.18 11.4 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain DUF1899 PF08953.11 CEH11683.1 - 6.2e-31 106.1 0.4 1.1e-30 105.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CEH11683.1 - 5.4e-18 64.6 2.6 2.5e-17 62.5 0.7 2.5 2 0 0 2 2 2 1 Type of WD40 repeat WD40 PF00400.32 CEH11683.1 - 1.3e-08 35.3 5.9 0.017 16.0 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH11683.1 - 2.9e-05 24.3 0.0 6.3 7.2 0.1 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEH11683.1 - 0.17 10.8 0.0 0.58 9.0 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SAP130_C PF16014.5 CEH11683.1 - 1.9 7.5 7.3 2.8 6.9 7.3 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Frataxin_Cyay PF01491.16 CEH11684.1 - 6.8e-35 119.4 0.0 9.1e-35 119.0 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Sacchrp_dh_NADP PF03435.18 CEH11685.1 - 6.4e-17 62.0 0.0 1.1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CEH11685.1 - 0.00044 19.8 0.0 0.0014 18.1 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CEH11685.1 - 0.012 15.6 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 CEH11685.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 CEH11685.1 - 0.064 12.6 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FGGY_C PF02782.16 CEH11686.1 - 1e-20 74.3 0.0 3e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CEH11686.1 - 1.2e-08 34.8 0.0 6.9e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain HSP70 PF00012.20 CEH11686.1 - 0.012 13.8 0.0 0.018 13.2 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein CART PF06373.11 CEH11686.1 - 0.045 14.0 0.1 7.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) SWI-SNF_Ssr4 PF08549.10 CEH11687.1 - 5.4e-05 22.1 0.4 5.4e-05 22.1 0.4 4.9 1 1 3 5 5 5 1 Fungal domain of unknown function (DUF1750) DUF1325 PF07039.11 CEH11689.1 - 3.3e-28 98.4 0.0 5.9e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 CEH11689.1 - 0.051 13.4 0.1 0.098 12.5 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain TUDOR PF00567.24 CEH11689.1 - 0.07 13.2 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Tudor domain Ndc1_Nup PF09531.10 CEH11689.1 - 0.53 8.9 6.3 0.82 8.3 6.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CytochromB561_N PF09786.9 CEH11689.1 - 1.3 7.9 9.7 1.8 7.5 9.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SOG2 PF10428.9 CEH11689.1 - 4 6.5 15.7 1.1 8.4 12.2 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein Pneumo_att_G PF05539.11 CEH11689.1 - 6.1 6.3 20.0 0.077 12.6 12.5 1.5 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G AA_permease_2 PF13520.6 CEH11690.1 - 3.4e-55 187.6 55.2 4.3e-55 187.3 55.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEH11690.1 - 6.9e-08 31.5 47.8 9.3e-08 31.1 47.8 1.1 1 0 0 1 1 1 1 Amino acid permease Pox_A14 PF05767.12 CEH11690.1 - 5.1 7.3 7.5 6.3 7.0 0.0 3.9 4 1 0 4 4 4 0 Poxvirus virion envelope protein A14 DUF3145 PF11343.8 CEH11691.1 - 0.035 13.6 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) zf-CCCH_2 PF14608.6 CEH11693.1 - 1.5e-18 66.5 40.1 1.5e-05 25.3 1.0 5.3 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Myb_DNA-binding PF00249.31 CEH11694.1 - 2e-14 53.5 6.6 1.4e-06 28.4 0.8 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH11694.1 - 1.7e-10 40.9 0.3 7.3e-06 26.1 0.0 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CEH11694.1 - 0.00043 20.6 1.8 0.00043 20.6 1.8 3.2 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain PseudoU_synth_2 PF00849.22 CEH11695.1 - 3e-22 79.4 0.0 6.9e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase UPF0020 PF01170.18 CEH11695.1 - 8.4e-13 48.4 0.0 3e-12 46.7 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 CEH11695.1 - 0.00011 21.8 1.2 0.082 12.3 0.0 2.9 2 1 1 3 3 3 2 RRNA methyltransferase AviRa K_oxygenase PF13434.6 CEH11695.1 - 0.064 12.4 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NUC173 PF08161.12 CEH11695.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 NUC173 domain DUF1682 PF07946.14 CEH11695.1 - 0.78 8.9 7.9 1.3 8.2 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) WD40 PF00400.32 CEH11696.1 - 0.004 18.0 15.5 2.5 9.1 0.0 6.1 6 1 0 6 6 6 2 WD domain, G-beta repeat RWD PF05773.22 CEH11696.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain TauD PF02668.16 CEH11697.1 - 2.8e-30 106.0 0.0 3.8e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family F-box-like PF12937.7 CEH11698.1 - 0.00053 19.8 0.3 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEH11698.1 - 0.022 14.6 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 F-box domain GMC_oxred_N PF00732.19 CEH11699.1 - 4.1e-34 118.3 0.1 4.6e-24 85.3 0.0 2.2 1 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 CEH11699.1 - 3.2e-33 115.3 0.0 5.2e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CEH11699.1 - 2e-07 30.5 0.1 0.0019 17.4 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 CEH11699.1 - 0.00011 21.6 0.0 0.00048 19.4 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 CEH11699.1 - 0.00011 22.4 0.1 0.00026 21.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CEH11699.1 - 0.00024 20.3 0.1 0.00043 19.5 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CEH11699.1 - 0.00046 19.9 0.5 0.0011 18.7 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEH11699.1 - 0.0024 17.1 0.3 0.0049 16.1 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CEH11699.1 - 0.0041 16.4 0.0 0.0082 15.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CEH11699.1 - 0.04 12.6 0.1 0.06 12.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CEH11699.1 - 0.064 12.5 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 CEH11699.1 - 0.077 13.3 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain CwfJ_C_1 PF04677.15 CEH11700.1 - 2.2e-26 92.1 0.0 3.3e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CEH11700.1 - 7.5e-08 33.2 0.1 1.9e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 FMO-like PF00743.19 CEH11701.1 - 6.4e-37 127.2 0.0 2.5e-15 55.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CEH11701.1 - 4.7e-10 39.2 0.0 2.3e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEH11701.1 - 4.7e-07 29.4 0.2 0.0032 16.8 0.0 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEH11701.1 - 9.4e-07 28.9 0.3 1.4e-05 25.1 0.3 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CEH11701.1 - 7e-05 23.0 0.2 0.0004 20.5 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEH11701.1 - 0.0021 17.7 0.6 0.94 9.0 0.0 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 CEH11701.1 - 0.035 13.2 0.0 16 4.5 0.0 3.3 4 0 0 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) TPR_8 PF13181.6 CEH11701.1 - 0.063 13.5 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Pyr_redox PF00070.27 CEH11701.1 - 0.12 12.9 0.3 26 5.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L11_N PF03946.14 CEH11702.1 - 2.8e-25 87.9 0.6 4.8e-25 87.2 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CEH11702.1 - 1.1e-23 83.4 0.2 2.2e-23 82.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Reprolysin_2 PF13574.6 CEH11703.1 - 6.7e-42 143.6 3.9 1.6e-41 142.4 3.9 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CEH11703.1 - 7.5e-40 137.2 8.8 7.5e-40 137.2 8.8 3.3 4 1 1 5 5 5 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CEH11703.1 - 1.9e-38 132.2 3.3 4e-38 131.1 3.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CEH11703.1 - 1.7e-14 54.3 26.4 1.7e-14 54.3 26.4 4.3 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 CEH11703.1 - 4e-14 53.2 0.1 2e-13 50.9 0.1 2.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 CEH11703.1 - 5e-07 30.0 0.1 1.4e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 CEH11703.1 - 1.3e-05 25.2 10.0 0.00024 21.1 8.9 3.2 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 CEH11703.1 - 0.00022 21.7 11.2 0.00022 21.7 11.2 3.8 2 1 2 4 4 4 1 ADAM cysteine-rich domain DUF4171 PF13775.6 CEH11703.1 - 0.63 10.5 4.1 0.8 10.1 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) Myc_target_1 PF15179.6 CEH11703.1 - 2.6 7.9 5.4 0.39 10.6 0.4 2.2 2 0 0 2 2 2 0 Myc target protein 1 DUF2420 PF10336.9 CEH11705.1 - 1.5e-09 37.9 0.0 3.3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Ribosomal_L28 PF00830.19 CEH11706.1 - 2e-16 59.9 1.1 3.9e-16 59.0 1.1 1.5 1 0 0 1 1 1 1 Ribosomal L28 family HMG_box PF00505.19 CEH11707.1 - 1.2e-12 48.1 0.2 2.5e-12 47.0 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEH11707.1 - 0.0011 19.6 0.0 0.0032 18.0 0.0 1.8 1 0 0 1 1 1 1 HMG-box domain MIF4G PF02854.19 CEH11709.1 - 5.3e-56 189.6 0.3 8.1e-56 189.0 0.3 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 CEH11709.1 - 2.7e-23 81.9 0.1 7.1e-23 80.6 0.1 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 CEH11709.1 - 7.5e-10 38.8 0.2 3.3e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 MA3 domain Bromodomain PF00439.25 CEH11711.1 - 3.3e-21 75.2 0.1 5.3e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 CEH11711.1 - 1.2e-08 34.8 0.1 4.5e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Bromodomain associated Lactamase_B_2 PF12706.7 CEH11712.1 - 4.2e-28 98.2 0.1 1.1e-27 96.9 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEH11712.1 - 0.00088 19.2 0.9 0.017 15.0 0.5 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Methyltransf_11 PF08241.12 CEH11713.1 - 4.7e-15 56.0 0.0 1.4e-14 54.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH11713.1 - 1.4e-12 48.2 0.0 4.5e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH11713.1 - 1.3e-05 25.8 0.0 3.2e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH11713.1 - 0.0011 18.7 0.0 0.0045 16.8 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH11713.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.8 CEH11713.1 - 0.0072 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) PRODH PF18327.1 CEH11713.1 - 0.32 11.2 2.4 0.63 10.3 2.4 1.4 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain Putative_PNPOx PF01243.20 CEH11714.1 - 2.2e-05 24.5 0.0 0.052 13.7 0.0 2.7 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase RabGAP-TBC PF00566.18 CEH11715.1 - 6.9e-54 182.7 0.0 9.2e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sugar_tr PF00083.24 CEH11717.1 - 2.1e-109 366.4 15.6 2.8e-109 366.0 15.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH11717.1 - 4e-24 85.2 16.0 4e-24 85.2 16.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CEH11717.1 - 2.3e-05 23.0 1.0 2.3e-05 23.0 1.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 CEH11717.1 - 0.00023 20.2 1.1 0.00044 19.3 1.1 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 CEH11717.1 - 0.00076 18.0 0.2 0.00076 18.0 0.2 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 CEH11717.1 - 0.031 13.1 3.9 0.27 10.1 0.0 3.2 3 1 1 4 4 4 0 MFS_1 like family EcKinase PF02958.20 CEH11719.1 - 3.5e-08 33.1 0.0 1.6e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase RINGv PF12906.7 CEH11720.1 - 1.8e-16 60.0 10.3 3.4e-16 59.1 10.3 1.5 1 0 0 1 1 1 1 RING-variant domain DUF4658 PF15555.6 CEH11720.1 - 0.064 13.4 0.5 0.64 10.1 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Colicin PF01024.19 CEH11720.1 - 0.37 10.7 0.9 0.7 9.8 0.2 1.8 2 0 0 2 2 2 0 Colicin pore forming domain zf-RING_2 PF13639.6 CEH11720.1 - 0.41 11.0 9.9 0.9 9.9 9.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 CEH11720.1 - 1.5 8.9 5.2 4.3 7.5 5.2 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CEH11720.1 - 7.7 6.8 6.9 16 5.7 6.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Pantoate_transf PF02548.15 CEH11721.1 - 1.4e-83 280.3 1.8 2.1e-82 276.4 1.8 2.1 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 CEH11721.1 - 0.037 13.5 0.0 0.11 11.9 0.0 1.9 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Cytochrom_C1 PF02167.15 CEH11722.1 - 1.6e-95 319.0 0.0 2.1e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CEH11722.1 - 0.0028 17.9 0.0 0.0067 16.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CEH11722.1 - 0.11 13.7 0.1 0.43 11.7 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c FAD_binding_2 PF00890.24 CEH11723.1 - 1.1e-122 410.1 2.6 1.5e-122 409.7 2.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CEH11723.1 - 4.2e-44 149.6 3.4 6.2e-44 149.1 3.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 CEH11723.1 - 3.2e-05 23.3 0.8 0.027 13.7 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 CEH11723.1 - 0.00069 18.8 1.0 0.16 11.0 2.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CEH11723.1 - 0.021 14.0 0.4 0.073 12.3 0.1 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEH11723.1 - 0.041 13.1 0.3 0.068 12.4 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 CEH11723.1 - 1.4 7.5 3.1 1.6 7.4 0.6 2.3 3 0 0 3 3 3 0 HI0933-like protein Coilin_N PF15862.5 CEH11724.1 - 1.2 8.9 10.9 1.4 8.7 4.6 2.2 2 0 0 2 2 2 0 Coilin N-terminus FAM176 PF14851.6 CEH11724.1 - 1.3 8.6 9.4 2.6 7.7 1.1 2.3 2 0 0 2 2 2 0 FAM176 family RR_TM4-6 PF06459.12 CEH11724.1 - 2.7 7.7 10.2 1 9.1 2.5 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 CEH11724.1 - 3 8.2 7.5 5.2 7.5 0.9 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Topoisom_I_N PF02919.15 CEH11727.1 - 6.6e-77 257.8 1.1 6.6e-77 257.8 1.1 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 CEH11727.1 - 9.3e-70 234.5 1.4 9.3e-70 234.5 1.4 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 CEH11727.1 - 1.1e-15 57.3 0.3 1.1e-12 47.7 0.1 2.9 2 0 0 2 2 2 2 C-terminal topoisomerase domain NAM-associated PF14303.6 CEH11727.1 - 0.025 15.3 0.2 0.025 15.3 0.2 6.0 4 2 0 5 5 5 0 No apical meristem-associated C-terminal domain DUF2489 PF10675.9 CEH11727.1 - 5 7.0 11.6 0.52 10.2 1.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2489) ACC_central PF08326.12 CEH11728.1 - 4.1e-197 656.8 0.0 5.1e-197 656.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CEH11728.1 - 7.8e-148 493.2 0.0 1.3e-147 492.4 0.0 1.4 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CEH11728.1 - 3.7e-53 180.2 0.0 6.6e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CEH11728.1 - 1.3e-27 96.5 0.1 5.2e-27 94.6 0.1 2.2 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEH11728.1 - 1.7e-20 73.1 0.0 2.6e-18 66.1 0.0 3.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CEH11728.1 - 2.3e-13 49.8 0.0 4.9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 CEH11728.1 - 0.00075 19.1 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CEH11728.1 - 0.0075 16.1 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like RimK PF08443.11 CEH11728.1 - 0.023 14.3 0.0 0.066 12.8 0.0 1.7 1 1 0 1 1 1 0 RimK-like ATP-grasp domain NAGLU_C PF12972.7 CEH11728.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain ATP-grasp_3 PF02655.14 CEH11728.1 - 0.19 11.8 0.0 0.64 10.1 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain ABA_GPCR PF12430.8 CEH11730.1 - 3.3e-39 134.5 1.6 3.3e-39 134.5 1.6 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CEH11730.1 - 3e-14 52.8 0.1 2.1e-13 50.2 0.0 2.3 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal EMC3_TMCO1 PF01956.16 CEH11731.1 - 2.3e-54 183.7 0.2 3e-54 183.3 0.2 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like RdRP PF05183.12 CEH11733.1 - 4.4e-104 349.2 0.0 6.3e-104 348.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase CRAL_TRIO PF00650.20 CEH11734.1 - 9.5e-30 103.4 0.0 1.4e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEH11734.1 - 4.4e-11 42.8 0.1 1.1e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CEH11734.1 - 9.9e-09 35.5 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RMI1_N PF08585.12 CEH11734.1 - 0.11 12.3 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein Flavin_Reduct PF01613.18 CEH11735.1 - 6.4e-19 68.5 5.7 1.8e-18 67.1 5.7 1.8 1 1 0 1 1 1 1 Flavin reductase like domain PTPA PF03095.15 CEH11736.1 - 3.5e-117 391.2 0.0 4.2e-117 390.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Snf7 PF03357.21 CEH11737.1 - 2.8e-43 147.5 11.8 3.4e-43 147.2 11.8 1.1 1 0 0 1 1 1 1 Snf7 Laminin_II PF06009.12 CEH11737.1 - 0.28 11.2 6.1 4 7.5 1.7 2.3 1 1 0 2 2 2 0 Laminin Domain II zf-C2H2 PF00096.26 CEH11739.1 - 8.3e-07 29.1 15.3 0.0018 18.6 4.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEH11739.1 - 0.00067 20.3 15.7 0.12 13.2 5.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEH11739.1 - 0.11 13.0 8.8 0.054 14.0 1.8 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 CEH11739.1 - 9.8 6.0 10.3 0.52 10.1 4.3 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type CENP-O PF09496.10 CEH11741.1 - 3e-16 60.1 0.0 5.2e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component GMC_oxred_N PF00732.19 CEH11743.1 - 4.7e-60 203.5 0.1 6.2e-60 203.1 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEH11743.1 - 1.3e-30 106.8 0.1 3.4e-30 105.4 0.1 1.8 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 CEH11743.1 - 0.0007 19.3 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CEH11743.1 - 0.011 14.9 0.9 0.019 14.1 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 CEH11743.1 - 0.034 14.4 0.1 0.11 12.7 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HHH PF00633.23 CEH11743.1 - 0.13 12.2 0.1 8.3 6.5 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif Alpha-amylase_C PF02806.18 CEH11744.1 - 5.3e-24 84.5 0.1 1.5e-23 83.1 0.1 1.8 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CEH11744.1 - 2.6e-17 62.9 0.0 5.6e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CEH11744.1 - 6e-15 55.6 0.0 2.1e-10 40.7 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain APG6 PF04111.12 CEH11745.1 - 2.4e-64 216.6 0.0 3.3e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CEH11745.1 - 8.6e-24 84.6 20.9 1.3e-23 84.0 20.9 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Rpr2 PF04032.16 CEH11745.1 - 0.15 12.4 0.5 0.45 10.8 0.0 2.0 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4407 PF14362.6 CEH11745.1 - 2.2 7.5 6.9 3.1 7.1 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 CEH11745.1 - 5.8 7.7 8.2 2.7 8.7 5.1 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ARPC4 PF05856.12 CEH11746.1 - 1.4e-78 262.3 2.9 1.5e-78 262.1 2.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Glyco_hydro_31 PF01055.26 CEH11747.1 - 1.4e-124 416.7 1.5 2.1e-124 416.1 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CEH11747.1 - 5.3e-19 68.3 0.6 8e-18 64.5 0.1 3.0 4 0 0 4 4 4 1 Galactose mutarotase-like DUF5110 PF17137.4 CEH11747.1 - 6.6e-05 23.1 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) KAR9 PF08580.10 CEH11748.1 - 1.3e-09 37.2 42.4 1.3e-09 37.2 42.4 3.9 2 1 2 4 4 4 1 Yeast cortical protein KAR9 GAS2 PF02187.17 CEH11748.1 - 0.027 14.5 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain DUF3915 PF13054.6 CEH11749.1 - 1.8 8.5 4.2 3.5 7.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3340 PF11818.8 CEH11749.1 - 3.4 7.8 16.1 9.4 6.4 16.1 1.7 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Vma12 PF11712.8 CEH11751.1 - 3.8e-24 85.3 0.2 5.5e-24 84.8 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3754 PF12576.8 CEH11751.1 - 0.2 11.6 0.2 0.33 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) DUF4231 PF14015.6 CEH11751.1 - 0.26 11.8 2.1 0.48 10.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF1690 PF07956.11 CEH11753.1 - 5.3e-21 75.5 13.5 5.3e-21 75.5 13.5 1.4 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) CHCH PF06747.13 CEH11753.1 - 0.079 13.1 0.3 0.13 12.5 0.3 1.3 1 0 0 1 1 1 0 CHCH domain PerC PF06069.11 CEH11753.1 - 0.19 12.0 2.6 0.3 11.4 1.6 1.7 1 1 0 1 1 1 0 PerC transcriptional activator Atg14 PF10186.9 CEH11753.1 - 2.1 7.3 13.1 2.6 7.0 13.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cauli_DNA-bind PF03310.13 CEH11753.1 - 2.6 8.1 6.2 5.1 7.2 4.9 2.2 2 1 0 2 2 2 0 Caulimovirus DNA-binding protein adh_short PF00106.25 CEH11754.1 - 1.8e-39 135.2 0.2 2.6e-39 134.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH11754.1 - 3.3e-21 75.9 0.1 4.5e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH11754.1 - 0.00053 20.0 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CEH11754.1 - 0.011 15.6 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CEH11754.1 - 0.023 13.8 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 CEH11754.1 - 0.088 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ARTD15_N PF18084.1 CEH11754.1 - 0.1 12.9 0.0 0.73 10.1 0.0 2.2 2 0 0 2 2 2 0 ARTD15 N-terminal domain tRNA_bind PF01588.20 CEH11755.1 - 2.2e-27 95.0 0.0 3.7e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 CEH11755.1 - 0.0015 18.6 0.2 0.0042 17.1 0.2 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CEH11755.1 - 0.19 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IHABP4_N PF16174.5 CEH11755.1 - 2.1 8.9 6.5 5.9 7.5 6.5 1.8 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal ABC_tran PF00005.27 CEH11756.1 - 3.5e-34 118.3 0.1 1.2e-33 116.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 CEH11756.1 - 2.6e-33 115.8 10.0 4.6e-33 115.0 10.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CEH11756.1 - 7.9e-05 22.2 0.0 0.0033 16.9 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CEH11756.1 - 0.00047 20.0 0.0 0.00067 19.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEH11756.1 - 0.0013 19.0 0.2 0.02 15.2 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CEH11756.1 - 0.0029 17.5 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CEH11756.1 - 0.0055 17.1 0.2 0.0055 17.1 0.2 2.5 3 1 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 CEH11756.1 - 0.012 15.4 0.9 0.046 13.5 0.0 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEH11756.1 - 0.033 14.1 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF2057 PF09829.9 CEH11756.1 - 0.23 11.6 0.1 0.23 11.6 0.1 4.0 4 2 0 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2057) BPD_transp_1 PF00528.22 CEH11756.1 - 0.37 10.5 10.4 0.087 12.5 1.8 3.1 3 0 0 3 3 3 0 Binding-protein-dependent transport system inner membrane component COesterase PF00135.28 CEH11757.1 - 1.3e-80 271.8 0.0 2e-80 271.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CEH11757.1 - 1.3e-07 31.7 0.1 7.3e-07 29.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEH11757.1 - 0.037 13.5 0.2 0.07 12.6 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PQ-loop PF04193.14 CEH11759.1 - 2.6e-21 75.1 6.7 9.2e-16 57.4 0.3 2.7 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 CEH11759.1 - 0.032 15.1 0.0 0.14 13.0 0.0 2.1 1 0 0 1 1 1 0 ER lumen protein retaining receptor DUF2417 PF10329.9 CEH11759.1 - 0.8 9.1 4.2 2.8 7.3 0.5 2.2 2 0 0 2 2 2 0 Region of unknown function (DUF2417) MFS_1 PF07690.16 CEH11760.1 - 5.7e-37 127.5 50.7 5.7e-37 127.5 50.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH11760.1 - 2.5e-11 43.1 1.7 2.5e-11 43.1 1.7 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter DUF5510 PF17629.2 CEH11760.1 - 0.081 12.9 0.2 0.081 12.9 0.2 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5510) Bax1-I PF01027.20 CEH11761.1 - 5e-30 104.9 11.7 6.7e-30 104.5 11.7 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Prenyltrans PF00432.21 CEH11762.1 - 2e-47 158.6 4.6 9.8e-10 38.0 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CEH11762.1 - 0.0028 16.8 0.0 16 4.5 0.1 3.9 1 1 4 5 5 5 3 Squalene-hopene cyclase N-terminal domain tRNA-synt_2 PF00152.20 CEH11763.1 - 6.5e-87 291.5 0.0 9e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEH11763.1 - 5.2e-13 48.8 0.0 1.2e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1154 PF06631.11 CEH11763.1 - 0.081 13.0 0.7 0.16 12.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) tRNA_anti_2 PF13742.6 CEH11763.1 - 0.088 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain An_peroxidase PF03098.15 CEH11765.1 - 1.9e-38 132.4 0.0 1.3e-25 90.0 0.1 3.9 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 CEH11765.1 - 9.6e-12 44.4 0.0 1.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.9 CEH11767.1 - 4.3e-81 272.4 0.0 1.1e-80 271.1 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 CEH11767.1 - 0.0053 16.7 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1917 PF08939.10 CEH11767.1 - 0.0083 16.1 0.4 0.05 13.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) Spo12 PF05032.12 CEH11768.1 - 5.8e-13 48.5 5.9 9.9e-13 47.8 5.9 1.4 1 0 0 1 1 1 1 Spo12 family MTS PF05175.14 CEH11769.1 - 5.9e-06 25.9 0.0 1.4e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 CEH11769.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CEH11769.1 - 0.0016 18.3 0.0 0.0046 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH11769.1 - 0.0035 18.0 0.0 0.01 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH11769.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 CEH11769.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Pox_MCEL PF03291.16 CEH11769.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Fungal_trans PF04082.18 CEH11770.1 - 4.2e-16 58.8 0.0 8e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH11770.1 - 2.5e-07 30.7 11.6 4.3e-07 29.9 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.6 CEH11771.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RCC1 PF00415.18 CEH11772.1 - 7.3e-39 132.2 5.8 4.1e-09 36.9 0.1 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEH11772.1 - 3e-20 71.5 13.7 7e-06 25.7 1.1 5.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 CEH11772.1 - 4.3e-08 32.9 8.1 4.3e-08 32.9 8.1 1.7 2 0 0 2 2 2 1 PHD-finger UPF0167 PF03691.14 CEH11772.1 - 0.043 13.6 0.6 0.079 12.8 0.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) PHD_4 PF16866.5 CEH11772.1 - 0.65 10.1 12.2 1.5 9.0 12.2 1.7 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 CEH11772.1 - 1.6 8.7 5.0 0.55 10.2 1.7 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Kelch_6 PF13964.6 CEH11772.1 - 7 7.1 5.4 12 6.4 0.4 3.5 4 0 0 4 4 4 0 Kelch motif Polysacc_deac_1 PF01522.21 CEH11774.1 - 1.1e-27 96.4 0.0 2e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Globin PF00042.22 CEH11774.1 - 0.21 12.2 0.0 15 6.2 0.0 2.4 2 0 0 2 2 2 0 Globin HSP70 PF00012.20 CEH11775.1 - 4.6e-61 206.8 2.3 1.1e-58 198.9 0.1 2.8 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CEH11775.1 - 0.096 11.5 0.3 0.21 10.4 0.3 1.5 1 0 0 1 1 1 0 MreB/Mbl protein G-alpha PF00503.20 CEH11777.1 - 1e-114 383.4 0.1 1.2e-114 383.2 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEH11777.1 - 1.2e-15 57.5 0.3 4.1e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEH11777.1 - 9.9e-05 21.8 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CEH11777.1 - 0.012 15.8 0.1 3.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 CEH11777.1 - 0.041 13.2 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family SMP_C2CD2L PF18696.1 CEH11777.1 - 0.07 12.9 0.1 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain AAA_29 PF13555.6 CEH11777.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CEH11777.1 - 0.13 12.3 0.1 9.5 6.3 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Methyltransf_16 PF10294.9 CEH11778.1 - 2.5e-11 43.6 0.0 3.2e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 CEH11778.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CEH11778.1 - 0.023 15.4 0.1 0.11 13.2 0.0 2.2 2 1 1 3 3 3 0 Methyltransferase domain PrmA PF06325.13 CEH11778.1 - 0.043 13.2 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CEH11778.1 - 0.047 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RhoGEF PF00621.20 CEH11779.1 - 0.0084 16.4 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain RhoGEF PF00621.20 CEH11780.1 - 2e-27 96.6 0.0 4.3e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 CEH11780.1 - 5.4e-06 26.2 0.0 9.5e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 BAR domain DUF2015 PF09435.10 CEH11781.1 - 4.5e-27 94.1 0.0 5.3e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Mod_r PF07200.13 CEH11782.1 - 3.5e-29 101.8 5.4 5.7e-29 101.1 5.4 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein SCP-1 PF05483.12 CEH11782.1 - 0.0013 16.8 0.3 0.0014 16.7 0.3 1.0 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) DUF4799 PF16056.5 CEH11782.1 - 0.01 15.1 0.2 0.01 15.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) Rootletin PF15035.6 CEH11782.1 - 0.024 14.7 5.2 0.032 14.3 5.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 CEH11782.1 - 0.026 15.1 0.5 0.052 14.2 0.5 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Mis12 PF05859.12 CEH11782.1 - 0.066 13.3 1.3 0.12 12.5 1.3 1.4 1 0 0 1 1 1 0 Mis12 protein Cnn_1N PF07989.11 CEH11782.1 - 0.091 12.9 2.4 0.23 11.7 2.4 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 polyprenyl_synt PF00348.17 CEH11784.1 - 6.3e-57 192.6 0.0 9.3e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase STAR_dimer PF16544.5 CEH11784.1 - 0.22 11.1 0.0 0.7 9.5 0.0 1.8 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein RIBIOP_C PF04950.12 CEH11785.1 - 1e-101 340.3 0.0 1.6e-101 339.6 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal DUF676 PF05057.14 CEH11785.1 - 1.6e-27 96.5 0.0 2.3e-23 82.8 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) AARP2CN PF08142.12 CEH11785.1 - 9.3e-18 64.1 0.0 2.6e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Pkinase PF00069.25 CEH11786.1 - 5.4e-70 235.8 0.0 6.3e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH11786.1 - 2.4e-34 118.8 0.0 3.1e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH11786.1 - 0.00051 19.5 0.0 0.00069 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEH11786.1 - 0.015 14.6 0.0 0.051 12.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH11786.1 - 0.022 14.7 0.0 0.059 13.3 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family FAD_binding_2 PF00890.24 CEH11786.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GtrA PF04138.14 CEH11786.1 - 0.093 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 GtrA-like protein eIF2A PF08662.11 CEH11787.1 - 2.1e-75 252.9 0.1 3e-74 249.1 0.0 2.7 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CEH11787.1 - 1.9e-05 25.3 0.7 1 10.4 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat CDV3 PF15359.6 CEH11787.1 - 0.069 13.6 3.1 0.28 11.7 0.5 2.5 1 1 1 2 2 2 0 Carnitine deficiency-associated protein 3 Proteasome_A_N PF10584.9 CEH11787.1 - 0.087 12.5 4.5 14 5.5 0.1 4.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Y_phosphatase PF00102.27 CEH11788.1 - 3.5e-52 177.3 0.0 3.8e-25 88.8 0.0 3.1 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 CEH11788.1 - 0.0025 18.3 0.0 0.21 12.1 0.0 2.8 3 0 0 3 3 3 1 Rhodanese-like domain DUF3106 PF11304.8 CEH11788.1 - 0.0088 16.5 0.3 0.021 15.3 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3106) Y_phosphatase3 PF13350.6 CEH11788.1 - 0.0088 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CEH11788.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain R3H-assoc PF13902.6 CEH11788.1 - 0.053 13.9 0.2 0.2 12.0 0.2 2.1 1 0 0 1 1 1 0 R3H-associated N-terminal domain PTPlike_phytase PF14566.6 CEH11788.1 - 0.096 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate AP_endonuc_2 PF01261.24 CEH11789.1 - 3.6e-15 56.0 0.0 9.4e-14 51.4 0.0 2.2 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel Dynein_light PF01221.18 CEH11790.1 - 4.9e-37 126.1 1.1 6.5e-37 125.7 1.1 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 CEH11790.1 - 0.033 13.7 0.2 0.035 13.6 0.2 1.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Response_reg PF00072.24 CEH11792.1 - 5.2e-14 52.4 0.2 9.5e-14 51.5 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain SprA-related PF12118.8 CEH11792.1 - 0.58 9.2 7.6 0.016 14.4 1.6 1.4 2 0 0 2 2 2 0 SprA-related family CPSase_L_D2 PF02786.17 CEH11793.1 - 3e-50 170.7 0.1 1.5e-26 93.2 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 CEH11793.1 - 2.6e-39 134.3 0.2 6.9e-38 129.7 0.2 2.7 2 1 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATPgrasp_Ter PF15632.6 CEH11793.1 - 2e-13 50.2 0.0 1.2e-05 25.1 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 CEH11793.1 - 1.5e-07 31.2 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CEH11793.1 - 0.00016 21.3 0.0 0.00043 19.9 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Halogen_Hydrol PF10112.9 CEH11793.1 - 0.023 14.7 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein LPD22 PF18834.1 CEH11793.1 - 0.059 13.6 0.0 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 Collagen_mid PF15984.5 CEH11793.1 - 0.18 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial collagen, middle region ExoD PF06055.12 CEH11793.1 - 0.19 11.1 0.0 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD Mito_carr PF00153.27 CEH11794.1 - 5.1e-63 209.0 1.8 7.5e-20 70.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein BTAD PF03704.17 CEH11794.1 - 0.078 13.4 0.3 0.13 12.7 0.3 1.3 1 0 0 1 1 1 0 Bacterial transcriptional activator domain RHH_1 PF01402.21 CEH11797.1 - 0.55 10.2 2.6 3 7.9 0.2 2.9 3 1 0 3 3 3 0 Ribbon-helix-helix protein, copG family UPF0029 PF01205.19 CEH11799.1 - 5.2e-11 42.8 0.2 4.7e-10 39.7 0.0 2.6 2 1 0 2 2 2 1 Uncharacterized protein family UPF0029 RabGAP-TBC PF00566.18 CEH11800.1 - 3.2e-28 98.9 0.0 4.6e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1952 PF09189.10 CEH11801.1 - 0.015 15.1 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) DUF4707 PF15806.5 CEH11801.1 - 0.14 11.0 0.9 0.14 11.1 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) Zds_C PF08632.10 CEH11802.1 - 4.4e-25 87.2 2.7 7.2e-25 86.5 2.7 1.3 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term RR_TM4-6 PF06459.12 CEH11802.1 - 9.6 5.9 7.9 21 4.8 7.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zn_clus PF00172.18 CEH11803.1 - 3.8e-09 36.5 9.3 6.9e-09 35.7 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CEH11803.1 - 0.0058 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FliX PF10768.9 CEH11803.1 - 0.35 11.4 3.5 0.35 11.4 0.2 2.6 3 0 0 3 3 3 0 Class II flagellar assembly regulator Glyco_hydro_32N PF00251.20 CEH11804.1 - 1.5e-43 149.5 0.0 2.5e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CEH11804.1 - 3.3e-28 98.7 0.0 4.4e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 CEH11804.1 - 4e-05 23.8 0.0 6.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) PSII_BNR PF14870.6 CEH11804.1 - 0.027 13.8 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 CEH11804.1 - 0.099 11.9 0.1 14 4.8 0.0 2.8 3 0 0 3 3 3 0 BNR repeat-like domain Sugar_tr PF00083.24 CEH11805.1 - 5.5e-56 190.3 15.8 7.2e-56 189.9 15.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH11805.1 - 2.5e-19 69.4 24.7 3.9e-19 68.8 24.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MerE PF05052.12 CEH11805.1 - 8.4 6.4 9.1 1.8 8.5 0.8 3.5 3 1 0 3 3 3 0 MerE protein Ribosomal_S11 PF00411.19 CEH11806.1 - 0.023 15.1 0.2 0.059 13.8 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein S11 Spt20 PF12090.8 CEH11806.1 - 0.24 11.0 2.0 0.39 10.3 2.0 1.2 1 0 0 1 1 1 0 Spt20 family Hamartin PF04388.12 CEH11806.1 - 0.55 8.8 4.0 0.9 8.1 4.0 1.3 1 0 0 1 1 1 0 Hamartin protein DUF4381 PF14316.6 CEH11807.1 - 2.4e-05 24.6 0.1 2.4e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) LPG_synthase_TM PF03706.13 CEH11807.1 - 0.042 13.4 0.2 0.042 13.4 0.2 1.7 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Cadherin_C_2 PF16492.5 CEH11807.1 - 0.1 13.4 0.1 0.55 11.0 0.1 2.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal MASE1 PF05231.14 CEH11807.1 - 0.15 11.2 0.9 0.22 10.6 0.9 1.2 1 0 0 1 1 1 0 MASE1 DUF2140 PF09911.9 CEH11807.1 - 0.15 11.6 0.3 0.57 9.7 0.7 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) CrgA PF06781.12 CEH11807.1 - 0.18 11.9 1.3 0.67 10.1 1.3 1.9 1 0 0 1 1 1 0 Cell division protein CrgA EphA2_TM PF14575.6 CEH11807.1 - 0.22 12.4 0.4 0.76 10.7 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ac110_PIF PF07280.11 CEH11807.1 - 0.64 9.9 2.1 0.95 9.3 2.1 1.2 1 0 0 1 1 1 0 Per os infectivity factor AC110 DUF4713 PF15831.5 CEH11807.1 - 1.2 9.7 3.2 2.1 8.8 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) Shisa PF13908.6 CEH11807.1 - 4.1 7.6 0.0 4.1 7.6 0.0 4.2 4 2 0 5 5 5 0 Wnt and FGF inhibitory regulator Fungal_trans PF04082.18 CEH11808.1 - 3.8e-18 65.5 0.0 5.7e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH11808.1 - 1e-06 28.8 8.4 1.9e-06 27.9 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 CEH11809.1 - 2.8e-19 70.0 0.0 1e-16 61.7 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CEH11809.1 - 4.7e-06 26.6 0.6 0.00087 19.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEH11809.1 - 0.00034 20.3 0.0 0.00072 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEH11809.1 - 0.011 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 CEH11809.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CEH11809.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CEH11809.1 - 0.042 13.8 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 CEH11809.1 - 0.057 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DAP3 PF10236.9 CEH11809.1 - 0.059 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CEH11809.1 - 0.11 12.8 1.9 0.27 11.6 0.2 2.5 2 1 1 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.23 CEH11809.1 - 0.21 11.6 0.1 0.89 9.6 0.1 2.0 2 0 0 2 2 2 0 Dynamin family zf-C2HC5 PF06221.13 CEH11810.1 - 2.1e-14 53.2 7.2 3.6e-14 52.5 7.2 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Ribosomal_60s PF00428.19 CEH11810.1 - 2.3 8.8 14.9 0.17 12.5 2.2 3.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein GtrA PF04138.14 CEH11811.1 - 0.061 13.6 0.9 0.061 13.6 0.9 1.8 2 0 0 2 2 2 0 GtrA-like protein Glyco_hydro_16 PF00722.21 CEH11812.1 - 3e-19 69.2 0.8 3e-19 69.2 0.8 2.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 DUF936 PF06075.12 CEH11812.1 - 1.1 8.2 30.7 1.4 7.8 30.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Utp14 PF04615.13 CEH11812.1 - 8.7 4.8 18.5 11 4.4 18.5 1.0 1 0 0 1 1 1 0 Utp14 protein Glyco_hydro_35 PF01301.19 CEH11813.1 - 1.3e-64 218.8 0.0 1.9e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 CEH11813.1 - 7.9e-45 152.1 0.7 1.2e-28 100.0 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 CEH11813.1 - 1e-26 93.9 2.0 1.7e-26 93.2 0.5 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 CEH11813.1 - 4.1e-15 55.1 0.1 1.2e-14 53.7 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 CEH11813.1 - 0.00012 21.7 0.0 0.00043 19.8 0.0 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) VHS PF00790.19 CEH11814.1 - 3.1e-25 88.7 0.1 6.8e-25 87.6 0.0 1.6 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 CEH11814.1 - 4.1e-16 58.3 0.0 7.9e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEH11814.1 - 7.2e-15 54.6 0.2 1.6e-14 53.5 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEH11814.1 - 1.5e-11 43.8 0.0 3.5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 CEH11814.1 - 1.3e-08 35.0 0.1 4.2e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 GAT domain Hrs_helical PF12210.8 CEH11814.1 - 0.00033 21.1 0.1 0.00073 20.0 0.1 1.5 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate UIM PF02809.20 CEH11814.1 - 0.054 13.4 0.4 0.054 13.4 0.4 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif Syntaxin_2 PF14523.6 CEH11814.1 - 0.099 13.0 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Syntaxin-like protein Nsp1_C PF05064.13 CEH11815.1 - 1.6e-28 98.8 1.6 2.6e-28 98.1 0.2 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region EAR PF07897.11 CEH11815.1 - 0.0054 16.3 12.7 0.023 14.3 0.1 4.8 4 0 0 4 4 4 1 Ethylene-responsive binding factor-associated repression FPP PF05911.11 CEH11815.1 - 0.012 13.8 0.5 0.024 12.8 0.0 1.5 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil Nucleoporin_FG PF13634.6 CEH11815.1 - 0.02 15.7 17.9 0.02 15.7 17.9 7.5 1 1 5 6 6 5 0 Nucleoporin FG repeat region NAM-associated PF14303.6 CEH11815.1 - 0.032 15.0 0.1 0.8 10.4 0.0 3.4 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain ATP-synt_B PF00430.18 CEH11815.1 - 0.12 12.4 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF4795 PF16043.5 CEH11815.1 - 0.17 11.5 0.2 0.32 10.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Fez1 PF06818.15 CEH11815.1 - 0.21 12.0 4.3 8.8 6.7 2.2 2.1 1 1 1 2 2 2 0 Fez1 XhlA PF10779.9 CEH11815.1 - 0.26 11.5 0.6 11 6.3 0.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Laminin_II PF06009.12 CEH11815.1 - 0.34 10.9 1.4 1.3 9.1 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II CENP-Q PF13094.6 CEH11815.1 - 0.34 11.1 3.4 0.37 11.0 0.2 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CLZ PF16526.5 CEH11815.1 - 0.83 10.1 7.6 8.1 6.9 0.1 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_GP20 PF06810.11 CEH11815.1 - 1.1 9.0 3.9 2.9 7.7 1.3 2.5 3 0 0 3 3 3 0 Phage minor structural protein GP20 DUF948 PF06103.11 CEH11815.1 - 1.2 9.4 2.4 29 5.0 0.1 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 CEH11815.1 - 2 8.9 4.3 23 5.5 0.0 2.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.6 CEH11815.1 - 2 8.0 4.0 1.3 8.7 1.2 1.8 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 CEH11815.1 - 3.3 7.8 3.7 5.1 7.2 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CEH11815.1 - 3.5 8.2 6.7 3.5 8.2 3.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 CEH11815.1 - 4.8 6.9 7.3 13 5.5 7.3 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family MscS_porin PF12795.7 CEH11815.1 - 4.9 6.6 12.2 1.6 8.2 7.7 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ATG16 PF08614.11 CEH11815.1 - 6.6 6.9 9.8 5.2 7.2 6.0 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) tRNA-synt_1 PF00133.22 CEH11816.1 - 3.4e-141 471.5 0.0 4.8e-141 471.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CEH11816.1 - 4e-18 65.3 0.0 1e-11 44.2 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CEH11816.1 - 8.1e-18 64.8 0.0 1.5e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 CEH11816.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 CEH11816.1 - 0.038 13.9 3.0 0.069 13.0 3.0 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS V-ATPase_G PF03179.15 CEH11817.1 - 1.2e-32 112.5 16.8 1.4e-32 112.3 16.8 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 CEH11817.1 - 0.027 14.6 15.2 0.027 14.6 15.2 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) YdfA_immunity PF12127.8 CEH11817.1 - 0.047 12.7 4.7 0.028 13.5 3.2 1.3 1 1 0 1 1 1 0 SigmaW regulon antibacterial Ntox34 PF15606.6 CEH11817.1 - 0.09 12.9 2.5 0.14 12.3 0.4 2.2 1 1 2 3 3 3 0 Bacterial toxin 34 Ureide_permease PF07168.11 CEH11817.1 - 1.6 7.4 4.7 1.8 7.2 4.7 1.0 1 0 0 1 1 1 0 Ureide permease DUF4407 PF14362.6 CEH11817.1 - 2.9 7.1 10.3 3.3 7.0 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 CEH11817.1 - 3.3 6.7 8.5 3.7 6.5 8.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 CEH11817.1 - 5.6 6.7 11.9 7 6.4 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) NAPRTase PF04095.16 CEH11818.1 - 8.4e-52 176.2 0.1 4.5e-50 170.5 0.1 2.2 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CEH11818.1 - 9.2e-33 113.3 0.0 1.5e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Retrotrans_gag PF03732.17 CEH11818.1 - 0.039 14.2 0.0 0.097 13.0 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Pertussis_S2S3 PF02918.15 CEH11818.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain FMN_dh PF01070.18 CEH11819.1 - 7.5e-108 360.6 0.0 8.8e-108 360.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CEH11819.1 - 3.5e-06 26.2 0.4 6.5e-06 25.4 0.4 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CEH11819.1 - 0.0015 17.7 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 CEH11819.1 - 0.0073 15.6 0.3 0.62 9.3 0.0 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG DSBA PF01323.20 CEH11820.1 - 2.4e-19 69.9 0.0 2.9e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Ribonuc_red_2_N PF08471.10 CEH11820.1 - 0.17 12.1 0.3 4.6 7.5 0.0 2.7 2 1 1 3 3 3 0 Class II vitamin B12-dependent ribonucleotide reductase Fungal_trans PF04082.18 CEH11822.1 - 2.6e-05 23.4 0.0 4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH11822.1 - 8.5e-05 22.6 12.2 0.00016 21.7 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_luciferase PF00296.20 CEH11823.1 - 1.1e-57 195.9 0.5 1.5e-57 195.5 0.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DSS1_SEM1 PF05160.13 CEH11823.1 - 0.015 15.4 0.1 0.032 14.3 0.1 1.6 1 0 0 1 1 1 0 DSS1/SEM1 family PGM_PMM_I PF02878.16 CEH11824.1 - 4.5e-39 133.3 0.0 7.4e-39 132.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CEH11824.1 - 4.6e-25 88.2 0.0 9.4e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CEH11824.1 - 1.4e-12 47.8 0.0 2.4e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CEH11824.1 - 9.2e-07 28.9 0.0 2.6e-05 24.3 0.0 2.5 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain FAA_hydrolase PF01557.18 CEH11825.1 - 8.2e-05 22.4 0.4 9e-05 22.2 0.4 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HHH PF00633.23 CEH11825.1 - 0.036 13.9 0.6 9.1 6.4 0.2 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Ntox10 PF15520.6 CEH11825.1 - 0.046 13.6 0.0 0.046 13.6 0.0 1.0 1 0 0 1 1 1 0 Novel toxin 10 FAA_hydrolase PF01557.18 CEH11826.1 - 1.9e-24 86.6 0.0 1.8e-12 47.4 0.0 2.0 2 0 0 2 2 2 2 Fumarylacetoacetate (FAA) hydrolase family Clathrin_bdg PF15045.6 CEH11826.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Pyrid_ox_like PF16242.5 CEH11827.1 - 4.2e-29 101.1 0.1 6.5e-29 100.4 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 CEH11827.1 - 2.1e-15 56.6 0.0 6.6e-15 55.1 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF374 PF04028.13 CEH11827.1 - 0.058 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Toxin_31 PF08119.11 CEH11828.1 - 1.1 9.0 4.6 1.9 8.3 0.4 2.1 2 0 0 2 2 2 0 Scorpion acidic alpha-KTx toxin family Gcn1_N PF12074.8 CEH11829.1 - 1.2e-72 245.2 0.1 1.2e-72 245.2 0.1 3.6 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 CEH11829.1 - 1.5e-24 83.9 33.1 0.15 12.4 0.1 19.1 22 0 0 22 22 21 5 HEAT repeat HEAT_EZ PF13513.6 CEH11829.1 - 3.8e-14 52.8 42.7 0.018 15.5 0.0 16.6 14 3 4 18 18 17 4 HEAT-like repeat Cnd1 PF12717.7 CEH11829.1 - 8.7e-14 51.9 0.0 0.15 12.1 0.0 9.9 8 1 2 11 11 11 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CEH11829.1 - 1.8e-12 47.3 0.1 2.9e-05 23.7 0.0 6.6 4 1 1 6 6 6 1 CLASP N terminal HEAT_2 PF13646.6 CEH11829.1 - 2.2e-11 44.0 57.0 0.0015 18.9 0.1 14.4 10 4 7 17 17 17 7 HEAT repeats Vac14_Fab1_bd PF12755.7 CEH11829.1 - 4.8e-09 36.7 0.0 1.7 9.3 0.0 6.9 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region ParcG PF10274.9 CEH11829.1 - 8.5e-06 26.0 0.6 1.6 8.8 0.0 5.4 5 1 0 6 6 6 2 Parkin co-regulated protein Ecm29 PF13001.7 CEH11829.1 - 2.7e-05 23.0 0.1 0.026 13.2 0.0 4.3 3 1 2 5 5 5 1 Proteasome stabiliser TIP120 PF08623.10 CEH11829.1 - 0.006 16.4 0.0 1.4 8.7 0.0 4.4 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) DUF4042 PF13251.6 CEH11829.1 - 0.033 13.9 1.6 5.2 6.7 0.0 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) DUF3437 PF11919.8 CEH11829.1 - 0.061 13.2 2.2 3.8 7.5 0.0 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF3437) DnaJ PF00226.31 CEH11830.1 - 4e-11 42.9 0.0 6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 CEH11831.1 - 8.2e-73 245.0 0.0 1e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH11831.1 - 5.9e-48 163.4 0.0 9.3e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CEH11831.1 - 1.6e-23 82.8 0.1 3.2e-23 81.8 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 CEH11831.1 - 5.6e-06 25.4 0.0 8.5e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEH11831.1 - 0.00016 21.1 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.12 CEH11831.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.14 CEH11831.1 - 0.042 13.2 0.5 0.4 10.0 0.1 2.1 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH11831.1 - 0.061 13.2 0.2 0.43 10.5 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEH11831.1 - 0.28 10.1 0.3 0.89 8.4 0.3 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Rad9 PF04139.13 CEH11833.1 - 8.3e-50 169.6 0.0 1.3e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Rad9 SNF5 PF04855.12 CEH11834.1 - 2.2e-51 175.0 0.3 4.7e-36 124.8 0.0 2.3 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 GATA PF00320.27 CEH11834.1 - 0.0012 18.4 1.0 0.0032 17.0 1.0 1.8 1 0 0 1 1 1 1 GATA zinc finger Aldo_ket_red PF00248.21 CEH11835.1 - 4e-28 98.4 0.0 9.4e-28 97.2 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Proteasome PF00227.26 CEH11836.1 - 5.1e-53 179.4 0.1 6.2e-53 179.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEH11836.1 - 9.8e-14 50.7 0.0 1.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cellulase PF00150.18 CEH11837.1 - 1.5e-12 47.5 0.3 2.4e-12 46.9 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 CEH11841.1 - 4.1e-59 200.1 0.0 2.3e-34 119.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH11841.1 - 2.3e-24 86.1 0.0 7.4e-21 74.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CEH11841.1 - 5.9e-05 22.5 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEH11841.1 - 0.0042 16.1 0.0 0.0064 15.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEH11841.1 - 0.014 15.3 0.1 0.014 15.3 0.1 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 CEH11841.1 - 0.038 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pyridox_oxase_2 PF12766.7 CEH11842.1 - 1.2e-18 67.5 0.0 1.9e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RPAP1_N PF08621.10 CEH11842.1 - 0.029 14.2 1.1 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 RPAP1-like, N-terminal Rep_fac_C PF08542.11 CEH11843.1 - 9.3e-21 74.1 0.0 1.9e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 CEH11843.1 - 3.9e-16 59.7 0.0 1.2e-15 58.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CEH11843.1 - 5.8e-12 45.7 0.0 1.7e-10 40.9 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 CEH11843.1 - 1.8e-06 27.8 0.1 6.4e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CEH11843.1 - 8.3e-06 26.1 0.4 2.8e-05 24.4 0.0 2.2 3 0 0 3 3 1 1 AAA C-terminal domain AAA_24 PF13479.6 CEH11843.1 - 9e-06 25.5 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEH11843.1 - 0.0001 22.2 0.0 0.00058 19.7 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CEH11843.1 - 0.00015 21.8 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEH11843.1 - 0.00033 20.1 0.0 0.00068 19.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CEH11843.1 - 0.0022 18.3 0.0 0.024 14.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEH11843.1 - 0.0023 18.3 0.0 0.015 15.7 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CEH11843.1 - 0.0052 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 CEH11843.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CEH11843.1 - 0.011 16.1 0.0 0.038 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CEH11843.1 - 0.023 14.3 0.0 0.054 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 CEH11843.1 - 0.036 14.0 0.0 0.08 12.9 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain RuvB_N PF05496.12 CEH11843.1 - 0.036 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CEH11843.1 - 0.039 14.0 0.0 0.15 12.1 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit MCM PF00493.23 CEH11843.1 - 0.057 12.5 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 CEH11843.1 - 0.061 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 CEH11843.1 - 0.093 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 CEH11843.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNase_PH PF01138.21 CEH11844.1 - 1e-29 103.7 1.0 1.7e-21 77.1 0.0 2.5 1 1 1 2 2 2 2 3' exoribonuclease family, domain 1 MutL_C PF08676.11 CEH11845.1 - 8.7e-22 77.5 0.0 2.8e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CEH11845.1 - 1.5e-17 63.4 0.0 3.6e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CEH11845.1 - 6.9e-12 45.4 0.0 1.5e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CEH11845.1 - 1.9e-06 28.3 0.1 5.6e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GIT_SHD PF08518.11 CEH11846.1 - 2e-24 84.9 7.7 3e-13 49.1 1.8 3.0 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 CEH11846.1 - 0.00036 20.6 0.1 0.00036 20.6 0.1 3.5 2 1 2 4 4 4 1 G protein-coupled receptor kinase-interacting protein 1 C term DUF812 PF05667.11 CEH11846.1 - 0.00046 19.2 17.4 0.00046 19.2 17.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF812) SlyX PF04102.12 CEH11846.1 - 0.01 16.4 4.5 0.01 16.4 4.5 5.5 3 2 2 5 5 5 0 SlyX DUF3584 PF12128.8 CEH11846.1 - 0.011 13.3 21.5 0.023 12.2 21.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KASH_CCD PF14662.6 CEH11846.1 - 0.055 13.3 29.9 0.043 13.7 27.8 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 CEH11846.1 - 0.28 10.4 21.5 0.6 9.4 5.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Tropomyosin PF00261.20 CEH11846.1 - 0.57 9.5 38.0 0.075 12.4 33.6 1.8 2 0 0 2 2 2 0 Tropomyosin EzrA PF06160.12 CEH11846.1 - 1.3 7.2 27.7 0.32 9.1 5.2 3.0 2 1 0 3 3 3 0 Septation ring formation regulator, EzrA YlqD PF11068.8 CEH11846.1 - 1.3 9.4 18.1 2 8.8 1.6 2.9 2 0 0 2 2 2 0 YlqD protein BLOC1_2 PF10046.9 CEH11846.1 - 2.5 8.5 22.1 0.21 11.9 2.3 4.7 2 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 CEH11846.1 - 3 7.4 33.8 0.47 10.0 16.2 2.7 2 1 1 3 3 3 0 Intermediate filament protein Cep57_CLD_2 PF14197.6 CEH11846.1 - 6.3 7.0 45.3 0.3 11.2 7.7 4.7 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 GPI2 PF06432.11 CEH11847.1 - 4.9e-34 118.0 0.0 6.9e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Zn_peptidase_2 PF04298.12 CEH11847.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Cellulase PF00150.18 CEH11848.1 - 2.6e-08 33.7 2.6 4.7e-08 32.8 2.6 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mucin PF01456.17 CEH11848.1 - 6.6 6.7 39.2 0.29 11.1 30.7 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein U1snRNP70_N PF12220.8 CEH11849.1 - 0.9 10.2 4.1 2.5 8.8 0.1 3.0 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Glyco_hydro_31 PF01055.26 CEH11850.1 - 5.3e-80 269.8 0.1 7.1e-80 269.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CEH11850.1 - 1.6e-11 44.3 0.1 3.6e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 CEH11850.1 - 0.028 14.7 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) PQ-loop PF04193.14 CEH11851.1 - 4.8e-26 90.3 3.6 1e-17 63.6 0.3 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF3054 PF11255.8 CEH11851.1 - 0.013 16.0 0.2 0.028 14.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) Abhydrolase_3 PF07859.13 CEH11852.1 - 1.7e-09 37.9 0.1 3.5e-08 33.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEH11852.1 - 0.061 12.2 0.2 0.41 9.4 0.2 2.0 1 1 0 1 1 1 0 Steryl acetyl hydrolase DUF2985 PF11204.8 CEH11854.1 - 8.6e-14 51.5 0.5 1.7e-09 37.7 0.0 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF2985) DUF2681 PF10883.8 CEH11854.1 - 0.039 14.3 0.2 2.2 8.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) CorA PF01544.18 CEH11854.1 - 0.14 11.5 0.0 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 CEH11854.1 - 0.22 11.5 2.1 0.6 10.2 0.1 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III bZIP_1 PF00170.21 CEH11856.1 - 1.4e-06 28.3 5.1 3e-06 27.2 5.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CEH11856.1 - 0.0068 16.5 3.9 0.014 15.4 3.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Chordopox_A30L PF06015.12 CEH11857.1 - 0.12 12.2 0.3 0.16 11.8 0.3 1.3 1 1 0 1 1 1 0 Chordopoxvirus A30L protein DUF4504 PF14953.6 CEH11858.1 - 1.6e-09 37.6 0.0 1.9e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4504) CENP-T_C PF15511.6 CEH11859.1 - 9.5e-09 35.4 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CEH11859.1 - 0.00011 22.4 0.0 0.00018 21.7 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CEH11859.1 - 0.00016 21.8 0.0 0.00023 21.3 0.0 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CEH11859.1 - 0.00098 19.5 0.0 0.0012 19.2 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 CEH11859.1 - 0.0011 19.4 0.0 0.0013 19.1 0.0 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CEH11859.1 - 0.11 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 CEH11860.1 - 9.9e-51 171.5 3.3 1.1e-50 171.3 3.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CEH11860.1 - 4.5e-05 23.7 0.0 7.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CEH11860.1 - 9.8e-05 22.4 0.8 0.00017 21.7 0.1 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CEH11860.1 - 0.00018 22.1 1.3 0.00024 21.7 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CEH11860.1 - 0.00095 19.4 0.1 0.0021 18.3 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEH11860.1 - 0.013 15.6 0.6 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEH11860.1 - 0.077 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Stress-antifung PF01657.17 CEH11861.1 - 0.089 13.4 0.0 0.25 12.0 0.0 1.8 2 0 0 2 2 2 0 Salt stress response/antifungal DUF5346 PF17281.2 CEH11862.1 - 0.033 14.2 0.6 0.051 13.6 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5346) FMN_dh PF01070.18 CEH11863.1 - 5.1e-106 354.6 0.0 6.4e-106 354.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CEH11863.1 - 6.8e-19 67.8 0.1 1.6e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CEH11863.1 - 0.00026 20.2 0.0 0.00045 19.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CEH11863.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CEH11863.1 - 0.028 13.8 0.1 0.045 13.1 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DUF4517 PF15006.6 CEH11863.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4517) PH_12 PF16457.5 CEH11865.1 - 8.8e-32 110.4 0.0 1.8e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 CEH11865.1 - 2.1e-24 86.6 0.0 3e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 CEH11865.1 - 9.3e-22 77.6 0.0 4.2e-21 75.5 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) SNO PF01174.19 CEH11867.1 - 2.6e-50 170.9 0.0 3.9e-37 127.9 0.0 3.0 2 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 CEH11867.1 - 1.6e-08 34.4 0.1 3.4e-08 33.3 0.0 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 CEH11867.1 - 0.0013 18.5 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 CEH11867.1 - 0.0029 17.3 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 CEH11867.1 - 0.0054 16.6 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family MCM_bind PF09739.9 CEH11868.1 - 1.7e-67 228.3 0.0 8.4e-51 173.1 0.0 3.1 1 1 2 3 3 3 3 Mini-chromosome maintenance replisome factor Bromodomain PF00439.25 CEH11869.1 - 0.02 15.0 0.0 0.086 12.9 0.0 1.9 2 0 0 2 2 2 0 Bromodomain Hexapep_2 PF14602.6 CEH11871.1 - 2.6e-11 43.1 15.4 2.5e-06 27.1 1.6 4.1 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 CEH11871.1 - 1.1e-10 40.7 24.1 1.9e-05 24.2 1.4 4.8 3 1 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) AA_permease PF00324.21 CEH11872.1 - 9.5e-66 222.3 37.3 5.4e-55 186.9 21.9 2.1 1 1 1 2 2 2 2 Amino acid permease adh_short_C2 PF13561.6 CEH11872.1 - 1.3e-27 96.9 0.0 2.4e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH11872.1 - 2.3e-23 82.7 0.0 4.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase SLC12 PF03522.15 CEH11872.1 - 1.1e-18 67.5 0.7 4.4e-10 39.2 0.0 3.4 3 0 0 3 3 3 3 Solute carrier family 12 KR PF08659.10 CEH11872.1 - 5.5e-06 26.4 0.1 1.8e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 KR domain FAD_binding_4 PF01565.23 CEH11873.1 - 3.4e-14 52.8 0.0 3.2e-06 26.9 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain BBE PF08031.12 CEH11873.1 - 3.7e-07 30.1 0.0 6.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Far-17a_AIG1 PF04750.14 CEH11875.1 - 2.4e-29 102.1 1.3 2.8e-29 101.9 1.3 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Aminotran_1_2 PF00155.21 CEH11877.1 - 1.1e-58 199.2 0.0 1.4e-58 198.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Trp_syntA PF00290.20 CEH11878.1 - 2e-86 289.0 0.2 3.6e-86 288.2 0.2 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 CEH11878.1 - 1.6e-49 168.9 0.7 4.5e-49 167.4 0.3 1.9 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme DUF4055 PF13264.6 CEH11878.1 - 0.13 12.5 0.1 17 5.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4055) His_biosynth PF00977.21 CEH11878.1 - 0.13 11.7 0.6 0.68 9.4 0.0 2.4 3 0 0 3 3 3 0 Histidine biosynthesis protein WD40 PF00400.32 CEH11879.1 - 0.0089 16.9 0.7 1.6 9.7 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat PMSR PF01625.21 CEH11880.1 - 1.7e-58 197.2 1.8 2e-58 196.9 1.8 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Cyclin PF08613.11 CEH11881.1 - 8.5e-37 127.0 9.3 8.6e-24 84.7 0.1 3.4 3 1 0 3 3 3 2 Cyclin GrpE PF01025.19 CEH11882.1 - 5.9e-45 152.9 0.0 8.8e-45 152.3 0.0 1.2 1 0 0 1 1 1 1 GrpE UCH PF00443.29 CEH11883.1 - 8.5e-72 241.7 0.0 1.3e-71 241.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CEH11883.1 - 4.6e-14 52.8 0.0 1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 CEH11883.1 - 2.6e-12 47.0 0.0 8.5e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Velvet PF11754.8 CEH11884.1 - 5.9e-45 154.2 0.3 1.1e-27 97.6 0.0 2.8 2 1 1 3 3 3 2 Velvet factor Velvet PF11754.8 CEH11885.1 - 7.7e-27 94.8 0.1 7.7e-27 94.8 0.1 1.7 2 0 0 2 2 2 1 Velvet factor TPT PF03151.16 CEH11887.1 - 8.6e-17 61.4 5.1 1e-16 61.2 5.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CEH11887.1 - 6.4e-05 23.2 7.4 9.1e-05 22.7 7.4 1.2 1 0 0 1 1 1 1 EamA-like transporter family Nuc_sug_transp PF04142.15 CEH11887.1 - 0.0033 16.7 0.1 0.0039 16.4 0.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 CEH11887.1 - 0.012 14.8 3.0 0.014 14.6 3.0 1.1 1 0 0 1 1 1 0 UAA transporter family Multi_Drug_Res PF00893.19 CEH11887.1 - 0.3 11.8 3.7 0.47 11.1 3.7 1.4 1 0 0 1 1 1 0 Small Multidrug Resistance protein TPT PF03151.16 CEH11888.1 - 2.4e-29 102.6 3.7 6.5e-29 101.2 3.7 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CEH11888.1 - 1.8e-06 28.2 8.9 0.00075 19.7 7.0 2.5 2 0 0 2 2 2 2 EamA-like transporter family Lectin_leg-like PF03388.13 CEH11889.1 - 4e-64 216.1 0.1 2e-33 115.7 0.1 2.1 1 1 1 2 2 2 2 Legume-like lectin family Bact_lectin PF18483.1 CEH11889.1 - 2.1e-10 41.0 0.0 6.2e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CEH11889.1 - 6.2e-08 32.5 0.0 1.2e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Legume lectin domain Phage_tail_S PF05069.13 CEH11889.1 - 0.057 13.3 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Phage virion morphogenesis family SR-25 PF10500.9 CEH11889.1 - 6.2 6.4 13.5 10 5.6 13.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_transf_22 PF03901.17 CEH11890.1 - 2.1e-47 162.3 13.4 2.7e-47 162.0 13.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Clat_adaptor_s PF01217.20 CEH11891.1 - 3.4e-55 185.9 2.9 3.7e-55 185.8 2.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FOXP-CC PF16159.5 CEH11892.1 - 0.0036 17.9 9.3 0.02 15.5 0.2 4.4 4 1 0 4 4 4 2 FOXP coiled-coil domain zf-Di19 PF05605.12 CEH11892.1 - 0.085 13.2 0.2 0.085 13.2 0.2 4.8 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DUF4899 PF16240.5 CEH11892.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) ADH_zinc_N_2 PF13602.6 CEH11894.1 - 7.6e-17 62.6 0.1 2e-16 61.2 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CEH11894.1 - 5.1e-13 49.1 0.3 7.9e-13 48.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH11894.1 - 0.016 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CEH11894.1 - 0.025 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus AAA_27 PF13514.6 CEH11894.1 - 0.13 11.8 0.0 3.1 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Torus PF16131.5 CEH11895.1 - 1.1e-05 26.1 5.1 0.0024 18.5 0.4 2.7 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 CEH11895.1 - 2.7e-05 23.8 9.2 0.00099 18.8 1.8 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 CEH11895.1 - 6.4e-05 22.8 8.3 0.00042 20.2 0.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEH11895.1 - 0.00094 19.2 15.1 0.0044 17.0 2.8 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 CEH11895.1 - 0.019 15.1 0.4 0.042 14.1 0.4 1.5 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CEH11895.1 - 1.9 9.1 12.6 0.15 12.6 2.9 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger HEAT_EZ PF13513.6 CEH11896.1 - 3.4e-35 120.0 20.5 2e-14 53.7 0.0 11.8 7 3 5 12 12 12 8 HEAT-like repeat HEAT PF02985.22 CEH11896.1 - 3.2e-26 89.2 7.3 0.0007 19.6 0.0 8.9 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 CEH11896.1 - 2e-21 76.2 0.3 1.2e-05 25.7 0.0 7.8 5 3 3 8 8 8 5 HEAT repeats IBN_N PF03810.19 CEH11896.1 - 4.4e-09 36.1 0.2 2.6e-08 33.7 0.1 2.5 2 0 0 2 2 1 1 Importin-beta N-terminal domain Arm PF00514.23 CEH11896.1 - 1.7e-08 34.2 2.0 0.13 12.4 0.0 5.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CEH11896.1 - 7e-08 33.0 0.0 0.0027 18.3 0.0 3.9 2 2 0 2 2 2 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CEH11896.1 - 2e-07 29.9 0.0 0.0069 15.0 0.0 3.9 4 0 0 4 4 4 2 Adaptin N terminal region DUF3437 PF11919.8 CEH11896.1 - 1.2e-05 25.2 0.1 0.022 14.7 0.0 3.6 4 0 0 4 4 3 1 Domain of unknown function (DUF3437) Cnd1 PF12717.7 CEH11896.1 - 2.2e-05 24.5 0.0 0.66 10.0 0.0 4.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 CEH11896.1 - 3.9e-05 23.0 4.8 0.47 9.5 0.0 4.4 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal Xpo1 PF08389.12 CEH11896.1 - 0.0059 16.7 0.0 0.5 10.4 0.0 3.2 1 1 0 1 1 1 1 Exportin 1-like protein RTP1_C1 PF10363.9 CEH11896.1 - 0.0097 16.1 0.3 0.56 10.4 0.0 3.7 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 CEH11896.1 - 0.048 13.8 0.1 19 5.3 0.0 3.4 3 1 1 4 4 3 0 Parkin co-regulated protein UME PF08064.13 CEH11896.1 - 0.1 12.5 0.1 9.7 6.2 0.0 3.8 4 1 0 4 4 4 0 UME (NUC010) domain DNA_pol_phi PF04931.13 CEH11896.1 - 0.13 10.3 8.0 0.26 9.4 8.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi UNC45-central PF11701.8 CEH11896.1 - 0.13 12.2 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central RNA_pol_3_Rpc31 PF11705.8 CEH11896.1 - 1.8 8.8 13.1 3.1 8.0 13.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRN3 PF05327.11 CEH11896.1 - 2 6.9 5.0 5 5.6 5.0 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 CEH11896.1 - 5.1 6.3 10.2 7.8 5.7 10.2 1.2 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 CEH11896.1 - 6 6.4 10.6 11 5.4 10.6 1.4 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 CEH11896.1 - 8.9 5.6 12.5 13 5.1 12.5 1.1 1 0 0 1 1 1 0 SDA1 Thiolase_N PF00108.23 CEH11897.1 - 2.2e-81 273.1 5.0 2.2e-81 273.1 5.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEH11897.1 - 8.6e-42 141.7 0.4 1.8e-41 140.6 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEH11897.1 - 0.00089 18.9 1.7 0.0094 15.6 0.2 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Kinesin PF00225.23 CEH11898.1 - 3.3e-71 239.9 0.0 5.9e-71 239.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEH11898.1 - 0.0032 17.4 0.0 0.0088 16.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_13 PF13166.6 CEH11898.1 - 0.11 11.1 4.6 0.19 10.4 4.6 1.3 1 0 0 1 1 1 0 AAA domain SlyX PF04102.12 CEH11898.1 - 0.85 10.3 9.0 1.2 9.8 3.1 3.2 2 1 1 3 3 3 0 SlyX Merozoite_SPAM PF07133.11 CEH11898.1 - 2.5 8.1 11.6 0.028 14.4 4.0 1.5 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) WD40 PF00400.32 CEH11900.1 - 4.4e-06 27.3 0.3 0.56 11.2 0.0 5.3 5 1 1 6 6 6 2 WD domain, G-beta repeat Tropomyosin_1 PF12718.7 CEH11901.1 - 3.7e-48 163.3 29.4 4.5e-48 163.0 29.4 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 CEH11901.1 - 6.4e-13 48.6 30.5 8e-06 25.4 8.1 3.6 1 1 2 3 3 3 3 Tropomyosin DUF3450 PF11932.8 CEH11901.1 - 5.3e-06 25.9 22.1 0.00024 20.5 11.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) Uso1_p115_C PF04871.13 CEH11901.1 - 2.5e-05 24.6 31.2 0.0018 18.6 13.1 2.1 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 CEH11901.1 - 8.7e-05 22.0 24.4 0.00095 18.6 8.3 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 CEH11901.1 - 0.00051 20.1 30.4 0.0019 18.2 9.3 3.1 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 CEH11901.1 - 0.00063 19.4 24.0 0.051 13.1 6.9 2.0 1 1 1 2 2 2 2 Intermediate filament protein Laminin_II PF06009.12 CEH11901.1 - 0.0013 18.7 15.7 0.0043 17.1 4.0 2.7 1 1 2 3 3 3 1 Laminin Domain II Myosin_tail_1 PF01576.19 CEH11901.1 - 0.0021 16.0 28.5 0.0025 15.7 28.5 1.0 1 0 0 1 1 1 1 Myosin tail DUF4200 PF13863.6 CEH11901.1 - 0.0022 18.4 30.0 0.11 12.9 13.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) DHR10 PF18595.1 CEH11901.1 - 0.0025 17.9 32.0 0.021 14.9 9.5 2.7 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain DUF1664 PF07889.12 CEH11901.1 - 0.0048 16.9 12.5 0.0064 16.5 2.1 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF1664) Cep57_CLD_2 PF14197.6 CEH11901.1 - 0.0093 16.0 2.7 0.0093 16.0 2.7 3.3 1 1 2 3 3 3 1 Centrosome localisation domain of PPC89 HMMR_N PF15905.5 CEH11901.1 - 0.011 15.3 24.2 0.02 14.4 24.2 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 CEH11901.1 - 0.017 14.0 28.8 0.085 11.7 11.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 CEH11901.1 - 0.021 14.8 28.5 0.63 10.1 13.7 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4691 PF15762.5 CEH11901.1 - 0.023 14.9 8.2 0.013 15.7 6.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4691) ADIP PF11559.8 CEH11901.1 - 0.023 14.8 25.9 1.4 9.0 9.6 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding KELK PF15796.5 CEH11901.1 - 0.041 14.3 4.0 0.041 14.3 4.0 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4164 PF13747.6 CEH11901.1 - 0.049 13.9 29.4 3.7 7.9 5.5 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Prefoldin PF02996.17 CEH11901.1 - 0.053 13.4 16.8 0.11 12.4 10.1 2.6 1 1 1 2 2 2 0 Prefoldin subunit BRE1 PF08647.11 CEH11901.1 - 0.059 13.5 25.7 0.8 9.8 8.7 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase KLRAQ PF10205.9 CEH11901.1 - 0.063 13.5 18.4 0.094 13.0 3.8 2.5 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF724 PF05266.14 CEH11901.1 - 0.068 13.0 24.1 0.37 10.6 6.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Fusion_gly PF00523.18 CEH11901.1 - 0.081 11.2 0.6 0.12 10.6 0.2 1.4 1 1 0 1 1 1 0 Fusion glycoprotein F0 TPR_MLP1_2 PF07926.12 CEH11901.1 - 0.093 12.8 32.2 4.1 7.5 9.3 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SHE3 PF17078.5 CEH11901.1 - 0.11 12.2 23.5 0.21 11.3 7.5 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Alanine_zipper PF11839.8 CEH11901.1 - 0.11 12.9 0.6 0.11 12.9 0.6 3.6 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein ERM PF00769.19 CEH11901.1 - 0.12 12.2 31.9 0.67 9.7 19.3 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family XhlA PF10779.9 CEH11901.1 - 0.14 12.4 22.6 1.2 9.3 4.7 3.6 1 1 1 3 3 3 0 Haemolysin XhlA Lebercilin PF15619.6 CEH11901.1 - 0.2 11.3 30.7 1.3 8.6 16.1 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 CEH11901.1 - 0.21 12.2 19.1 0.22 12.2 1.1 4.2 1 1 3 4 4 4 0 SlyX Fez1 PF06818.15 CEH11901.1 - 0.28 11.6 24.7 0.1 13.1 20.1 1.9 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 CEH11901.1 - 0.29 11.3 12.9 0.29 11.3 7.1 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MAD PF05557.13 CEH11901.1 - 0.29 9.4 25.3 0.24 9.7 12.2 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein PsbQ PF05757.11 CEH11901.1 - 0.32 10.7 11.4 0.79 9.4 2.6 2.2 1 1 1 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF932 PF06067.11 CEH11901.1 - 0.36 10.6 15.4 8.1 6.1 15.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF932) LMBR1 PF04791.16 CEH11901.1 - 0.38 9.6 13.1 0.49 9.2 13.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Tup_N PF08581.10 CEH11901.1 - 0.41 11.0 20.7 0.23 11.8 3.1 2.8 1 1 2 3 3 3 0 Tup N-terminal APG6_N PF17675.1 CEH11901.1 - 0.42 11.1 36.0 9.6 6.7 21.3 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region CHDCT2 PF08074.11 CEH11901.1 - 0.44 10.7 10.1 0.1 12.8 5.2 1.9 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain HrpB7 PF09486.10 CEH11901.1 - 0.52 10.7 25.2 64 3.9 2.6 3.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.11 CEH11901.1 - 0.75 10.0 28.6 2.1 8.5 12.5 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 CEH11901.1 - 0.77 9.8 27.6 1.3 9.1 14.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 CEH11901.1 - 0.95 8.7 21.9 2 7.7 21.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 CEH11901.1 - 0.97 9.7 18.6 0.68 10.2 12.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Med21 PF11221.8 CEH11901.1 - 1 9.6 22.0 0.27 11.5 12.2 2.5 1 1 0 2 2 2 0 Subunit 21 of Mediator complex IZUMO PF15005.6 CEH11901.1 - 1.5 9.4 7.6 1 9.9 5.0 1.9 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Jnk-SapK_ap_N PF09744.9 CEH11901.1 - 1.5 9.1 30.8 2.7 8.2 13.4 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 EF-G-binding_N PF07299.11 CEH11901.1 - 1.6 9.3 8.9 0.55 10.8 2.8 2.5 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DASH_Hsk3 PF08227.11 CEH11901.1 - 1.7 9.1 5.4 9.3 6.7 0.4 2.8 3 0 0 3 3 2 0 DASH complex subunit Hsk3 like NPV_P10 PF05531.12 CEH11901.1 - 1.8 9.1 8.1 1.3 9.5 0.4 3.4 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 CEH11901.1 - 2.2 7.3 24.0 0.22 10.6 7.9 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 CEH11901.1 - 2.2 9.0 17.6 4 8.1 3.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Swi5 PF07061.11 CEH11901.1 - 2.8 8.1 24.6 1.7 8.8 2.2 4.1 1 1 3 4 4 4 0 Swi5 HAUS-augmin3 PF14932.6 CEH11901.1 - 3.2 7.3 24.8 0.3 10.6 16.2 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Seryl_tRNA_N PF02403.22 CEH11901.1 - 3.3 8.0 24.3 7.1 6.9 13.4 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Exonuc_VII_L PF02601.15 CEH11901.1 - 3.5 7.1 19.2 9.2 5.7 19.2 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit HemX PF04375.14 CEH11901.1 - 3.6 6.8 19.9 4.7 6.4 6.4 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase YscO PF07321.12 CEH11901.1 - 3.7 7.5 29.5 2.2 8.2 8.6 3.1 1 1 2 3 3 3 0 Type III secretion protein YscO TMF_TATA_bd PF12325.8 CEH11901.1 - 3.7 7.8 22.9 5.5 7.2 11.3 2.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF16 PF01519.16 CEH11901.1 - 5 7.7 16.2 3.3 8.2 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Lectin_N PF03954.14 CEH11901.1 - 5 6.9 12.3 2 8.2 2.8 3.0 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain TMPIT PF07851.13 CEH11901.1 - 5.1 6.2 18.1 4.4 6.5 5.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein BST2 PF16716.5 CEH11901.1 - 5.2 7.7 21.8 15 6.2 1.8 3.5 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 FlaC_arch PF05377.11 CEH11901.1 - 5.7 7.4 16.9 2.2 8.7 0.6 4.3 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) DUF812 PF05667.11 CEH11901.1 - 5.7 5.7 24.8 12 4.7 24.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Rho_Binding PF08912.11 CEH11901.1 - 6.7 7.6 27.5 4.1 8.3 3.9 3.6 1 1 3 4 4 4 0 Rho Binding DUF641 PF04859.12 CEH11901.1 - 7.2 7.0 18.4 0.43 10.9 3.1 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.19 CEH11901.1 - 7.6 4.3 18.2 0.54 8.1 7.0 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family YdfA_immunity PF12127.8 CEH11901.1 - 7.8 5.5 7.3 1.7 7.6 4.1 1.6 1 1 0 1 1 1 0 SigmaW regulon antibacterial She9_MDM33 PF05546.11 CEH11901.1 - 7.9 6.2 17.6 1.3e+02 2.2 0.9 3.1 1 1 1 2 2 2 0 She9 / Mdm33 family DUF2730 PF10805.8 CEH11901.1 - 9.3 6.4 13.4 0.92 9.6 1.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) CENP-N PF05238.13 CEH11902.1 - 7.4e-28 98.0 0.0 6.2e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 Kinetochore protein CHL4 like DUF3350 PF11830.8 CEH11902.1 - 0.22 11.9 0.4 2.1 8.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) CoA_transf_3 PF02515.17 CEH11903.1 - 8.5e-39 133.7 0.0 2.5e-38 132.2 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III PUB_1 PF18486.1 CEH11903.1 - 0.36 10.7 5.6 0.46 10.4 2.7 2.5 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain DUF4078 PF13300.6 CEH11904.1 - 2.2e-15 56.7 6.4 2.2e-15 56.7 6.4 4.6 5 1 0 5 5 5 1 Domain of unknown function (DUF4078) Tcf25 PF04910.14 CEH11905.1 - 2.2e-93 313.1 0.0 3.1e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 D123 PF07065.14 CEH11905.1 - 8.4e-88 294.4 0.0 7.6e-65 219.1 0.0 2.5 2 0 0 2 2 2 2 D123 CPBP PF02517.16 CEH11906.1 - 1.4e-16 60.6 5.1 1.4e-16 60.6 5.1 2.0 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease RhoGAP PF00620.27 CEH11907.1 - 2.4e-46 157.3 0.0 4.9e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 CEH11907.1 - 2.5e-15 56.5 0.6 6.1e-15 55.3 0.1 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2316 PF10078.9 CEH11907.1 - 0.041 14.1 1.5 0.47 10.7 0.4 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) EF-hand_7 PF13499.6 CEH11908.1 - 3.4e-10 40.2 3.6 5.2e-06 26.8 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEH11908.1 - 1.2e-07 31.0 4.5 0.00025 20.7 0.6 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CEH11908.1 - 8.7e-05 22.3 2.2 0.0018 18.1 0.3 2.6 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CEH11908.1 - 0.0012 18.2 4.7 7.6 6.3 0.4 4.3 4 1 0 4 4 4 3 EF hand EF-hand_11 PF08976.11 CEH11908.1 - 0.012 16.4 0.0 1.1 10.1 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain RRF PF01765.19 CEH11909.1 - 2.8e-36 124.9 0.0 5.8e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 Ribosome recycling factor E1-E2_ATPase PF00122.20 CEH11910.1 - 2.8e-49 167.1 1.1 2.8e-49 167.1 1.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEH11910.1 - 9e-24 84.2 1.6 9.9e-24 84.0 0.1 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CEH11910.1 - 3.6e-22 79.7 4.3 8.3e-22 78.5 2.9 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEH11910.1 - 9.3e-13 47.7 0.0 1.9e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEH11910.1 - 1.5e-10 41.0 0.0 1.2e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEH11910.1 - 0.001 18.9 0.8 0.0042 16.9 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEH11910.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF5437 PF17505.2 CEH11912.1 - 0.25 11.4 2.6 7.2 6.7 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5437) Sad1_UNC PF07738.13 CEH11913.1 - 2.2e-23 82.7 0.0 4.4e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal EVC2_like PF12297.8 CEH11913.1 - 0.67 8.6 5.2 1.3 7.7 5.2 1.4 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein zf-PHD-like PF15446.6 CEH11914.1 - 0.0026 17.4 4.9 0.18 11.4 0.3 2.4 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain DUF4611 PF15387.6 CEH11914.1 - 0.0028 17.8 17.8 0.11 12.8 4.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4611) YycH PF07435.11 CEH11914.1 - 0.0029 16.7 9.5 0.056 12.4 1.0 2.1 2 0 0 2 2 2 2 YycH protein YafO_toxin PF13957.6 CEH11914.1 - 0.0082 16.2 4.9 0.23 11.5 0.6 3.0 3 0 0 3 3 3 1 Toxin YafO, type II toxin-antitoxin system gp37_C PF12604.8 CEH11914.1 - 0.019 14.7 0.0 7.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Tail fibre protein gp37 C terminal DUF568 PF04526.13 CEH11914.1 - 0.046 14.5 2.0 7.1 7.4 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF568) CYTL1 PF15153.6 CEH11914.1 - 0.13 12.3 0.1 25 4.8 0.0 2.4 2 0 0 2 2 2 0 Cytokine-like protein 1 DUF2704 PF10866.8 CEH11914.1 - 0.13 12.2 0.9 3 7.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2704) DUF4634 PF15465.6 CEH11914.1 - 0.26 11.6 1.5 26 5.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4634) SipA_VBS PF17985.1 CEH11914.1 - 0.32 11.0 3.8 15 5.7 0.3 2.5 2 0 0 2 2 2 0 SipA vinculin binding site DUF3022 PF11226.8 CEH11914.1 - 0.46 11.0 10.6 4.6 7.8 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) FAST_2 PF08368.12 CEH11914.1 - 0.51 11.2 5.9 15 6.4 0.6 2.8 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 GAS PF13851.6 CEH11914.1 - 0.95 8.8 34.2 3 7.1 13.3 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4410 PF14366.6 CEH11914.1 - 4.5 7.2 11.7 12 5.8 2.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) Nbl1_Borealin_N PF10444.9 CEH11915.1 - 0.019 14.6 0.6 0.019 14.6 0.6 1.6 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal DUF2911 PF11138.8 CEH11915.1 - 0.07 13.0 0.3 0.078 12.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) DUF1192 PF06698.11 CEH11915.1 - 0.28 11.3 2.9 0.38 10.8 0.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Sel1 PF08238.12 CEH11917.1 - 9.6e-22 76.9 41.7 2.9e-06 27.8 0.5 8.9 10 0 0 10 10 10 4 Sel1 repeat ANAPC1 PF12859.7 CEH11917.1 - 0.17 12.4 3.9 10 6.7 0.7 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 DUF4834 PF16118.5 CEH11917.1 - 0.78 10.7 2.9 2.1 9.3 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF2615 PF11027.8 CEH11917.1 - 1 9.5 2.8 1.3 9.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) Rft-1 PF04506.13 CEH11918.1 - 6.9e-83 279.1 0.0 1.1e-81 275.1 0.0 2.1 1 1 0 1 1 1 1 Rft protein Thymidylate_kin PF02223.17 CEH11919.1 - 2.5e-45 154.5 0.0 3.3e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 CEH11919.1 - 0.0014 18.9 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEH11919.1 - 0.0043 17.2 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CEH11919.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 CEH11919.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PPK2 PF03976.14 CEH11919.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) KH_8 PF17903.1 CEH11920.1 - 2.8e-29 101.0 0.0 6.3e-29 99.9 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain PAP2 PF01569.21 CEH11920.1 - 6.9e-25 87.4 3.5 6.9e-25 87.4 3.5 2.7 3 0 0 3 3 3 1 PAP2 superfamily KH_1 PF00013.29 CEH11920.1 - 0.00042 20.1 0.0 0.00088 19.1 0.0 1.5 1 0 0 1 1 1 1 KH domain Ytca PF17090.5 CEH11920.1 - 0.1 13.2 0.5 0.28 11.7 0.5 1.8 1 1 0 1 1 1 0 Uncharacterised protein family PAP2_3 PF14378.6 CEH11920.1 - 0.17 11.5 14.8 0.023 14.4 9.7 2.2 2 1 0 2 2 2 0 PAP2 superfamily CNDH2_M PF16869.5 CEH11920.1 - 0.25 12.0 5.1 0.25 12.0 0.5 2.6 2 0 0 2 2 2 0 PF16858 PRIMA1 PF16101.5 CEH11920.1 - 1.2 9.2 3.5 4.2 7.4 0.2 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF1761 PF08570.10 CEH11920.1 - 1.7 8.9 6.5 3.3 8.0 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) Methyltransf_11 PF08241.12 CEH11921.1 - 3.8e-13 49.9 0.0 1.1e-12 48.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH11921.1 - 2e-12 47.6 0.1 8e-12 45.7 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEH11921.1 - 1.4e-11 44.2 0.0 2.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CEH11921.1 - 9.7e-07 28.8 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH11921.1 - 1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH11921.1 - 6.6e-06 26.8 0.0 1.5e-05 25.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 CEH11921.1 - 0.039 13.6 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CheR PF01739.18 CEH11921.1 - 0.1 12.0 0.0 0.27 10.7 0.0 1.6 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain PAGK PF15284.6 CEH11922.1 - 0.058 13.3 0.3 0.13 12.1 0.3 1.7 1 0 0 1 1 1 0 Phage-encoded virulence factor CCT_2 PF09425.10 CEH11925.1 - 0.0054 16.6 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Divergent CCT motif CCT PF06203.14 CEH11925.1 - 0.015 15.4 0.4 0.027 14.5 0.4 1.4 1 0 0 1 1 1 0 CCT motif RTP1_C1 PF10363.9 CEH11927.1 - 2.5e-26 92.0 0.8 6.8e-26 90.6 0.3 2.1 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 CEH11927.1 - 0.008 16.2 0.1 0.039 14.0 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CEH11927.1 - 0.05 12.1 0.2 0.13 10.8 0.0 1.7 2 0 0 2 2 2 0 Adaptin N terminal region Adaptin_N PF01602.20 CEH11929.1 - 3.7e-87 293.1 6.4 4.2e-87 292.9 6.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CEH11929.1 - 4.1e-32 111.5 4.9 4.1e-31 108.2 0.2 2.6 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEH11929.1 - 6.4e-07 29.7 5.2 0.012 16.0 0.2 3.8 2 2 2 4 4 4 4 HEAT repeats HEAT PF02985.22 CEH11929.1 - 0.00048 20.2 2.0 0.3 11.5 0.1 4.0 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.23 CEH11929.1 - 0.019 15.0 2.4 0.34 11.0 0.1 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 CEH11929.1 - 0.023 13.9 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain pPIWI_RE_Y PF18156.1 CEH11929.1 - 0.071 13.5 0.0 2.9 8.3 0.0 2.6 2 1 0 2 2 2 0 pPIWI_RE three-gene island domain Y DUF5578 PF17741.1 CEH11929.1 - 0.17 11.2 3.8 0.78 9.1 0.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5578) RasGEF_N_2 PF14663.6 CEH11929.1 - 0.33 11.4 3.0 3.6 8.0 0.1 2.7 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CTP_synth_N PF06418.14 CEH11930.1 - 3.7e-119 396.9 0.1 4.9e-119 396.5 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CEH11930.1 - 7.5e-37 126.9 0.0 1.4e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SR-25 PF10500.9 CEH11931.1 - 0.0031 17.2 3.7 0.0031 17.2 3.7 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Serglycin PF04360.12 CEH11931.1 - 0.0059 16.6 1.0 0.0059 16.6 1.0 1.6 2 0 0 2 2 2 1 Serglycin NAM-associated PF14303.6 CEH11931.1 - 0.02 15.6 1.8 0.02 15.6 1.8 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain TMEM51 PF15345.6 CEH11931.1 - 5.5 6.8 9.1 26 4.5 9.1 2.0 1 1 0 1 1 1 0 Transmembrane protein 51 Aldolase_II PF00596.21 CEH11932.1 - 1.6e-42 145.6 0.8 2.3e-42 145.1 0.8 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Abhydrolase_6 PF12697.7 CEH11933.1 - 6.8e-10 39.9 7.4 2.2e-09 38.3 4.4 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH11933.1 - 4.3e-08 32.7 0.2 1.7e-07 30.8 0.2 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH11933.1 - 3.4e-06 26.9 0.1 3.3e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CEH11933.1 - 0.00015 22.0 0.3 0.00045 20.4 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_3 PF07859.13 CEH11933.1 - 0.00017 21.5 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEH11933.1 - 0.0002 20.9 0.0 0.00052 19.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1100 PF06500.11 CEH11933.1 - 0.0029 16.4 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) LIP PF03583.14 CEH11933.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase DUF2974 PF11187.8 CEH11933.1 - 0.092 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.12 CEH11933.1 - 0.13 10.9 0.0 0.64 8.6 0.0 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) 2OG-FeII_Oxy_2 PF13532.6 CEH11934.1 - 2.8e-30 106.0 0.1 5.2e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PLA2_B PF01735.18 CEH11934.1 - 4e-19 68.4 0.0 6.5e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain CCD PF07860.11 CEH11935.1 - 0.17 12.0 4.1 2.7 8.1 0.7 2.9 2 1 1 3 3 3 0 WisP family C-Terminal Region Amidohydro_1 PF01979.20 CEH11938.1 - 0.018 14.4 0.0 0.094 12.0 0.0 1.8 1 1 0 1 1 1 0 Amidohydrolase family p450 PF00067.22 CEH11939.1 - 2.3e-42 145.3 0.0 3.1e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TBCA PF02970.16 CEH11940.1 - 4.3e-17 62.2 5.0 5e-17 62.0 5.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Pet100 PF09803.9 CEH11941.1 - 5.8e-13 49.2 0.1 6.5e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 Pet100 Hist_deacetyl PF00850.19 CEH11942.1 - 1.7e-54 185.4 0.0 4.3e-40 138.1 0.0 2.3 2 0 0 2 2 2 2 Histone deacetylase domain Pro_isomerase PF00160.21 CEH11943.1 - 2.1e-50 171.1 0.1 2.4e-50 170.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cyt_bd_oxida_II PF02322.15 CEH11945.1 - 0.022 14.1 8.9 0.028 13.8 8.9 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II CoA_binding_3 PF13727.6 CEH11945.1 - 0.051 13.6 0.7 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 CoA-binding domain UTP25 PF06862.12 CEH11946.1 - 2.6e-152 507.9 0.0 3.1e-152 507.7 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 NAD_binding_4 PF07993.12 CEH11947.1 - 4.3e-61 206.3 0.0 1e-59 201.8 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 CEH11947.1 - 3.4e-60 203.8 0.0 6.5e-60 202.9 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme adh_short PF00106.25 CEH11947.1 - 4.9e-51 173.0 4.4 1.4e-50 171.5 4.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH11947.1 - 5.7e-40 137.3 1.0 1.5e-39 136.0 1.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CEH11947.1 - 6e-20 71.7 0.1 6.6e-13 48.7 0.0 3.3 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 CEH11947.1 - 6.7e-19 68.5 3.8 1.4e-15 57.7 2.3 3.1 3 0 0 3 3 2 2 KR domain NAD_binding_10 PF13460.6 CEH11947.1 - 1.8e-11 44.3 0.7 1.1e-06 28.7 0.5 3.3 3 0 0 3 3 3 2 NAD(P)H-binding PP-binding PF00550.25 CEH11947.1 - 2.2e-10 40.7 0.0 5.1e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 CEH11947.1 - 5.3e-09 35.5 0.3 3.3e-05 23.0 0.0 3.1 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CEH11947.1 - 5.5e-07 29.0 2.3 0.0069 15.6 1.2 3.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CEH11947.1 - 9.5e-06 24.9 1.9 0.026 13.6 0.0 3.3 3 1 0 3 3 3 2 RmlD substrate binding domain AMP-binding_C PF13193.6 CEH11947.1 - 5.7e-05 24.0 0.2 0.00019 22.4 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain THF_DHG_CYH_C PF02882.19 CEH11947.1 - 0.00048 19.5 1.2 0.003 16.9 0.3 2.3 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 CEH11947.1 - 0.00095 19.0 1.6 0.0031 17.3 0.8 2.2 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 CEH11947.1 - 0.0022 17.5 0.2 1.2 8.4 0.2 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CEH11947.1 - 0.013 15.0 0.9 3.5 7.1 0.0 2.9 3 0 0 3 3 3 0 NmrA-like family ApoL PF05461.11 CEH11947.1 - 1 8.6 3.4 1.9 7.8 3.4 1.3 1 0 0 1 1 1 0 Apolipoprotein L CDT1_C PF16679.5 CEH11948.1 - 1.8e-09 37.9 9.0 1.9e-09 37.8 0.0 3.1 3 0 0 3 3 3 2 DNA replication factor Cdt1 C-terminal domain CDT1 PF08839.11 CEH11948.1 - 7.2e-08 32.9 0.0 2.1e-06 28.1 0.0 2.9 2 1 0 2 2 2 1 DNA replication factor CDT1 like LSM PF01423.22 CEH11949.1 - 8.1e-18 63.9 0.1 1e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CEH11949.1 - 0.087 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Hfq protein eIF-5_eIF-2B PF01873.17 CEH11950.1 - 2e-40 137.3 0.0 3e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CEH11950.1 - 9.5e-20 70.5 1.7 9.5e-20 70.5 1.7 2.2 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon OS-D PF03392.13 CEH11950.1 - 0.06 13.4 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D RXT2_N PF08595.11 CEH11950.1 - 5.2 7.1 6.1 2.6 8.1 0.4 2.4 2 1 0 2 2 2 0 RXT2-like, N-terminal Hydrolase_4 PF12146.8 CEH11951.1 - 7.7e-30 103.9 0.0 4.5e-17 62.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH11951.1 - 7.7e-12 45.4 0.0 6.2e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH11951.1 - 2.6e-07 31.5 0.2 3.7e-07 31.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CEH11951.1 - 0.00015 21.5 0.1 0.00028 20.6 0.1 1.4 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 CEH11951.1 - 0.00051 19.7 0.0 0.69 9.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Asp2 PF16929.5 CEH11951.1 - 0.006 15.6 0.1 0.0096 14.9 0.1 1.2 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter Peptidase_S10 PF00450.22 CEH11951.1 - 0.072 12.5 0.0 3.1 7.1 0.0 2.3 3 0 0 3 3 3 0 Serine carboxypeptidase FMN_dh PF01070.18 CEH11952.1 - 2e-104 349.4 0.0 2.3e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CEH11952.1 - 2.3e-08 33.5 0.4 4e-08 32.7 0.4 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 CEH11952.1 - 6.3e-06 25.8 0.1 0.00046 19.7 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 CEH11952.1 - 7.3e-06 25.5 1.1 0.0027 17.1 0.2 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 CEH11952.1 - 3.6e-05 23.1 0.2 5.8e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CEH11952.1 - 0.0001 21.8 0.3 0.00015 21.3 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 CEH11952.1 - 0.009 15.3 0.1 0.025 13.8 0.0 1.7 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase Dus PF01207.17 CEH11952.1 - 0.023 13.8 0.1 0.045 12.8 0.1 1.4 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) Abhydrolase_6 PF12697.7 CEH11953.1 - 3.8e-15 57.1 1.1 5.8e-15 56.5 1.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEH11953.1 - 4.9e-14 52.6 0.4 1.2e-12 48.1 0.2 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH11953.1 - 1.1e-09 38.0 0.1 2.4e-09 36.8 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 CEH11953.1 - 0.014 15.7 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus AAA_11 PF13086.6 CEH11954.1 - 2.1e-61 208.0 2.1 3e-61 207.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 CEH11954.1 - 6.9e-47 159.6 0.0 1.1e-46 158.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH11954.1 - 1.4e-09 38.5 0.1 3e-08 34.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEH11954.1 - 1.8e-09 37.6 8.1 2.4e-05 24.2 0.0 3.5 2 2 2 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 CEH11954.1 - 1.8e-09 37.7 1.1 0.092 12.5 0.2 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CEH11954.1 - 3.6e-05 24.0 0.1 0.00069 19.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CEH11954.1 - 0.00014 21.2 1.2 0.16 11.2 0.0 3.3 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 CEH11954.1 - 0.00027 20.7 0.0 0.00088 19.1 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 CEH11954.1 - 0.00031 20.8 0.0 0.011 15.8 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CEH11954.1 - 0.00039 20.0 0.0 0.039 13.5 0.0 2.3 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 CEH11954.1 - 0.00055 20.4 0.8 0.0042 17.5 0.8 2.7 1 1 0 1 1 1 1 AAA ATPase domain UvrD_C PF13361.6 CEH11954.1 - 0.00057 19.4 0.3 0.047 13.1 0.1 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 CEH11954.1 - 0.00081 19.0 0.3 0.0036 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CEH11954.1 - 0.0018 17.8 0.0 1.4 8.3 0.0 2.6 3 0 0 3 3 3 2 PhoH-like protein Glyco_tranf_2_3 PF13641.6 CEH11954.1 - 0.022 14.7 0.1 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase like family 2 AAA_7 PF12775.7 CEH11954.1 - 0.026 14.0 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 CEH11954.1 - 0.061 13.8 0.4 0.38 11.2 0.2 2.2 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Phage_holin_2_4 PF16082.5 CEH11957.1 - 0.059 13.1 2.3 2.7 7.8 0.7 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF4201 PF13870.6 CEH11958.1 - 0.22 11.2 6.2 0.52 10.0 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Pinin_SDK_memA PF04696.13 CEH11960.1 - 7.3e-09 35.8 4.4 7.3e-09 35.8 4.4 4.8 3 1 1 4 4 4 1 pinin/SDK/memA/ protein conserved region TPR_MLP1_2 PF07926.12 CEH11960.1 - 0.027 14.5 1.0 0.027 14.5 1.0 5.2 5 0 0 5 5 5 0 TPR/MLP1/MLP2-like protein Smg4_UPF3 PF03467.15 CEH11961.1 - 1.1e-49 168.8 0.0 1.1e-49 168.8 0.0 3.6 2 2 1 3 3 3 1 Smg-4/UPF3 family DUF5553 PF17707.1 CEH11961.1 - 0.013 14.9 0.1 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5553) RAB3GAP2_C PF14656.6 CEH11961.1 - 0.16 10.2 0.7 0.3 9.3 0.7 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus BRCT PF00533.26 CEH11962.1 - 4.6e-07 30.1 0.0 1e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CEH11962.1 - 0.00027 21.3 0.0 0.00064 20.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CEH11962.1 - 0.036 14.0 0.1 0.087 12.8 0.1 1.7 1 0 0 1 1 1 0 twin BRCT domain PNP_UDP_1 PF01048.20 CEH11962.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily Ribonuclease_T2 PF00445.18 CEH11963.1 - 2.6e-39 135.3 0.2 3.8e-39 134.8 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DPBB_1 PF03330.18 CEH11964.1 - 2e-08 34.4 0.0 4.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase MMS19_C PF12460.8 CEH11966.1 - 4e-66 223.9 0.6 1.6e-65 221.9 0.2 2.2 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 CEH11966.1 - 4.7e-64 216.5 5.1 3.9e-63 213.5 0.0 4.1 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II TRH PF05438.12 CEH11966.1 - 4.8 6.9 9.6 1.7 8.3 3.4 2.3 2 0 0 2 2 2 0 Thyrotropin-releasing hormone (TRH) DUF3402 PF11882.8 CEH11967.1 - 4.6e-108 362.3 1.5 2e-106 356.9 1.6 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 CEH11967.1 - 1.2e-58 198.6 0.0 2.1e-58 197.8 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein Pterin_4a PF01329.19 CEH11967.1 - 0.026 14.7 0.0 0.065 13.4 0.0 1.6 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase Nup88 PF10168.9 CEH11968.1 - 5.9e-19 67.4 5.9 3.1e-10 38.6 0.0 3.2 3 0 0 3 3 3 3 Nuclear pore component YlqD PF11068.8 CEH11968.1 - 0.091 13.1 12.5 2.4 8.5 0.1 2.5 2 0 0 2 2 2 0 YlqD protein DUF919 PF06034.11 CEH11968.1 - 0.17 11.7 3.1 0.62 9.9 3.1 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Syntaxin_2 PF14523.6 CEH11968.1 - 0.23 11.8 6.0 0.33 11.4 2.3 2.5 2 0 0 2 2 2 0 Syntaxin-like protein Nup54 PF13874.6 CEH11968.1 - 0.79 9.8 12.1 1.8 8.7 11.6 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 CLZ PF16526.5 CEH11968.1 - 2.6 8.5 9.7 9.6 6.6 0.6 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1690 PF07956.11 CEH11968.1 - 3 8.2 9.3 6 7.3 7.6 2.4 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) TolA_bind_tri PF16331.5 CEH11968.1 - 3.9 7.6 15.5 27 4.9 0.1 3.3 2 1 1 3 3 3 0 TolA binding protein trimerisation Baculo_PEP_C PF04513.12 CEH11968.1 - 4.2 7.4 5.2 48 4.0 0.8 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 CEH11968.1 - 8 6.8 6.7 35 4.7 0.3 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) HTH_15 PF12324.8 CEH11969.1 - 0.2 11.7 2.4 4.5 7.3 0.2 4.2 4 0 0 4 4 4 0 Helix-turn-helix domain of alkylmercury lyase bZIP_1 PF00170.21 CEH11972.1 - 0.082 13.0 7.6 0.1 12.7 1.4 2.7 2 0 0 2 2 2 0 bZIP transcription factor DIMCO_N PF16844.5 CEH11972.1 - 0.53 10.7 3.1 0.81 10.0 1.0 2.2 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Nbl1_Borealin_N PF10444.9 CEH11972.1 - 0.73 9.5 6.7 0.16 11.6 1.1 2.7 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal MCC-bdg_PDZ PF10506.9 CEH11972.1 - 2.1 8.4 9.2 0.55 10.3 0.8 3.0 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome MCU PF04678.13 CEH11972.1 - 9.3 6.3 6.3 2.2 8.3 0.7 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter 3Beta_HSD PF01073.19 CEH11975.1 - 2.2e-09 36.7 0.0 3.5e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CEH11975.1 - 7.2e-08 31.9 0.2 0.0019 17.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 CEH11975.1 - 1.3e-07 31.4 0.4 3e-07 30.2 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CEH11975.1 - 2.4e-07 30.8 2.3 4.1e-07 30.1 2.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CEH11975.1 - 0.00048 19.6 0.5 0.00084 18.8 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CEH11975.1 - 0.0038 16.8 2.4 0.022 14.3 0.8 2.7 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 CEH11975.1 - 0.0054 16.2 0.3 0.045 13.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CEH11975.1 - 0.0087 16.0 0.7 0.023 14.6 0.6 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CEH11975.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CEH11975.1 - 0.031 13.4 0.0 0.058 12.5 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain WW PF00397.26 CEH11976.1 - 2.2e-05 24.4 2.8 2.2e-05 24.4 2.8 2.3 2 0 0 2 2 2 1 WW domain PIN_4 PF13638.6 CEH11977.1 - 2.5e-05 24.6 0.0 4.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 PIN domain Methyltransf_16 PF10294.9 CEH11978.1 - 0.018 14.8 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Lysine methyltransferase ADH_N PF08240.12 CEH11981.1 - 3.2e-22 78.5 3.4 5.7e-22 77.7 3.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEH11981.1 - 2e-14 53.7 0.0 4.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CEH11981.1 - 1.5e-05 24.4 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 CEH11981.1 - 0.0014 19.7 0.0 0.0033 18.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CEH11981.1 - 0.0017 17.8 0.2 0.004 16.5 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CEH11981.1 - 0.014 15.9 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 CEH11981.1 - 0.017 15.0 1.6 0.02 14.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 CEH11981.1 - 0.2 11.3 0.0 0.43 10.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NADH_4Fe-4S PF10589.9 CEH11981.1 - 2.8 8.1 5.8 2.4 8.3 3.4 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Sec6 PF06046.13 CEH11982.1 - 9.8e-144 479.8 0.2 1.3e-143 479.4 0.2 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 MgsA_C PF12002.8 CEH11983.1 - 3e-49 167.2 0.0 6.6e-49 166.1 0.0 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal TPK_catalytic PF04263.16 CEH11983.1 - 1.2e-30 106.0 0.0 3.2e-30 104.6 0.0 1.7 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain AAA_assoc_2 PF16193.5 CEH11983.1 - 2.4e-24 85.5 0.3 7.5e-24 83.9 0.3 1.8 1 0 0 1 1 1 1 AAA C-terminal domain TPK_B1_binding PF04265.14 CEH11983.1 - 1.2e-12 47.3 0.0 2.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain RuvB_N PF05496.12 CEH11983.1 - 2.7e-11 43.4 0.0 6.3e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 CEH11983.1 - 2.3e-10 41.0 0.1 9.5e-10 39.0 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEH11983.1 - 7.9e-07 29.4 0.1 4.6e-06 26.9 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CEH11983.1 - 3.9e-06 27.4 1.9 8.7e-05 23.0 1.6 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CEH11983.1 - 1.9e-05 24.7 0.2 6e-05 23.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEH11983.1 - 4.4e-05 23.0 0.1 0.021 14.2 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CEH11983.1 - 6.5e-05 23.0 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEH11983.1 - 0.00034 21.2 0.0 0.00093 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CEH11983.1 - 0.00063 19.9 0.0 0.0022 18.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 CEH11983.1 - 0.0012 19.0 0.1 0.0027 17.9 0.1 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 CEH11983.1 - 0.0013 18.4 0.3 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_30 PF13604.6 CEH11983.1 - 0.0023 17.7 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH11983.1 - 0.0026 18.1 0.2 0.11 12.8 0.0 2.6 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 CEH11983.1 - 0.0033 16.9 0.0 0.0092 15.4 0.0 1.8 1 0 0 1 1 1 1 Bacterial TniB protein Sgf11 PF08209.11 CEH11983.1 - 0.0062 16.1 0.9 0.048 13.2 0.6 2.2 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) DUF815 PF05673.13 CEH11983.1 - 0.0074 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 CEH11983.1 - 0.0087 16.6 0.5 0.052 14.1 0.0 2.4 3 0 0 3 3 2 1 ABC transporter AAA_7 PF12775.7 CEH11983.1 - 0.016 14.7 0.3 0.059 12.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 CEH11983.1 - 0.018 15.0 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 CEH11983.1 - 0.027 14.2 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CEH11983.1 - 0.033 14.6 0.0 0.11 12.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.6 CEH11983.1 - 0.038 14.1 0.2 0.18 12.0 0.2 2.4 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 CEH11983.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 CEH11983.1 - 0.068 12.9 0.0 0.068 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEH11983.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf_UBZ PF18439.1 CEH11983.1 - 0.084 12.5 0.4 0.19 11.4 0.4 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger AAA_13 PF13166.6 CEH11983.1 - 0.1 11.2 1.1 0.21 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 CEH11983.1 - 0.12 12.3 0.1 0.38 10.6 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CEH11983.1 - 0.14 11.3 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 CEH11983.1 - 0.19 11.6 0.1 4.3 7.2 0.1 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 CEH11983.1 - 0.34 11.1 3.4 0.31 11.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain DUF812 PF05667.11 CEH11983.1 - 0.38 9.6 5.1 0.6 8.9 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Med3 PF11593.8 CEH11983.1 - 0.47 9.6 27.2 0.043 13.0 22.1 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ndc1_Nup PF09531.10 CEH11983.1 - 3.8 6.1 9.2 6.7 5.3 9.2 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_pp85 PF04637.12 CEH11983.1 - 6 5.2 8.8 10 4.4 8.8 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Hamartin PF04388.12 CEH11983.1 - 6.8 5.2 15.3 10 4.6 15.3 1.2 1 0 0 1 1 1 0 Hamartin protein DCP1 PF06058.13 CEH11984.1 - 5e-23 81.3 0.0 7.8e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family Phage_fiber_2 PF03406.13 CEH11984.1 - 0.068 12.7 0.4 0.068 12.7 0.4 2.6 3 0 0 3 3 3 0 Phage tail fibre repeat 2OG-FeII_Oxy_3 PF13640.6 CEH11990.1 - 0.043 14.7 1.8 0.54 11.2 0.8 2.7 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily SAB PF04382.13 CEH11993.1 - 0.023 14.8 0.3 0.049 13.7 0.3 1.5 1 0 0 1 1 1 0 SAB domain E1-E2_ATPase PF00122.20 CEH11994.1 - 0.052 13.1 0.0 0.075 12.6 0.0 1.3 1 1 0 1 1 1 0 E1-E2 ATPase PT-HINT PF07591.11 CEH11994.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Pretoxin HINT domain RPN13_C PF16550.5 CEH11995.1 - 0.071 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 UCH-binding domain Caskin-Pro-rich PF16907.5 CEH11996.1 - 0.1 13.1 4.7 0.21 12.1 4.7 1.5 1 0 0 1 1 1 0 Proline rich region of Caskin proteins zf-C2H2 PF00096.26 CEH11998.1 - 3.6e-05 24.0 5.4 0.0092 16.4 1.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CEH11998.1 - 0.00048 20.4 2.4 0.039 14.2 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CEH11998.1 - 0.01 16.1 4.7 0.56 10.5 1.5 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CEH11998.1 - 0.011 16.4 1.1 0.011 16.4 1.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger Ima1_N PF09779.9 CEH11998.1 - 0.053 14.4 0.1 0.094 13.6 0.1 1.3 1 0 0 1 1 1 0 Ima1 N-terminal domain zf-HC2 PF13490.6 CEH11998.1 - 0.4 11.0 0.2 0.4 11.0 0.2 2.5 3 0 0 3 3 3 0 Putative zinc-finger Nrap_D4 PF17405.2 CEH11999.1 - 2.9e-47 160.8 0.0 4.7e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 CEH11999.1 - 4.6e-34 117.5 0.3 1.6e-33 115.8 0.1 2.1 3 0 0 3 3 3 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 CEH11999.1 - 1.6e-32 112.8 0.0 3.7e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 CEH11999.1 - 3.9e-31 107.9 0.2 5.5e-29 100.9 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 CEH11999.1 - 3.4e-30 105.0 0.0 5.4e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap PF03813.14 CEH11999.1 - 1.7e-18 67.1 0.0 3.1e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Sedlin_N PF04628.13 CEH12000.1 - 1.6e-23 83.2 0.0 6.5e-21 74.8 0.0 2.1 2 0 0 2 2 2 2 Sedlin, N-terminal conserved region Ribosomal_60s PF00428.19 CEH12000.1 - 6.6 7.4 10.6 5.9 7.5 0.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein RIBIOP_C PF04950.12 CEH12001.1 - 5e-88 295.3 0.2 1.2e-87 294.1 0.0 1.6 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CEH12001.1 - 4.4e-29 100.4 0.2 2.7e-28 97.9 0.0 2.2 2 0 0 2 2 2 1 AARP2CN (NUC121) domain Peptidase_M16_C PF05193.21 CEH12002.1 - 1.6e-40 139.1 0.0 2.1e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CEH12002.1 - 1.8e-20 73.4 0.0 3.6e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) WD40 PF00400.32 CEH12004.1 - 9.1e-08 32.7 0.3 5.1 8.1 0.1 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat U1snRNP70_N PF12220.8 CEH12005.1 - 0.002 18.7 11.0 0.031 14.9 1.3 4.4 4 0 0 4 4 4 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RXT2_N PF08595.11 CEH12005.1 - 5.8 6.9 16.8 5.2 7.1 9.6 3.0 2 1 0 2 2 2 0 RXT2-like, N-terminal SSP160 PF06933.11 CEH12005.1 - 6.8 4.8 9.1 12 4.0 9.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1640 PF07798.11 CEH12006.1 - 5.1e-52 176.5 3.0 5.8e-52 176.3 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.18 CEH12006.1 - 0.0043 17.2 1.5 0.023 14.9 1.5 2.3 1 1 0 1 1 1 1 Homeobox associated leucine zipper DUF2163 PF09931.9 CEH12006.1 - 0.01 16.1 0.4 0.015 15.5 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) TolA_bind_tri PF16331.5 CEH12006.1 - 0.034 14.2 1.3 0.58 10.3 0.9 2.5 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF5082 PF16888.5 CEH12006.1 - 0.061 13.6 2.0 2.3 8.5 0.0 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) Baculo_PEP_C PF04513.12 CEH12006.1 - 0.11 12.5 2.1 1 9.4 1.0 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GreA_GreB_N PF03449.15 CEH12006.1 - 0.22 11.7 6.6 0.054 13.7 2.9 1.9 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Ada_Zn_binding PF02805.16 CEH12007.1 - 1.7e-09 37.6 2.3 4.7e-09 36.2 2.3 1.8 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 CEH12007.1 - 0.009 16.1 0.0 0.048 13.8 0.0 2.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family CAP_N PF01213.19 CEH12007.1 - 1.4 8.3 4.5 0.62 9.5 0.2 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal 4HBT_3 PF13622.6 CEH12009.1 - 5.4e-56 190.6 0.2 6.4e-56 190.4 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CEH12009.1 - 4.5e-29 100.9 0.0 1.1e-21 77.1 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase PTPRCAP PF15713.5 CEH12011.1 - 0.031 14.6 15.4 0.037 14.3 15.4 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Macoilin PF09726.9 CEH12011.1 - 0.26 9.8 12.6 0.31 9.6 12.6 1.0 1 0 0 1 1 1 0 Macoilin family DUF2052 PF09747.9 CEH12011.1 - 1.9 8.5 14.3 2.4 8.2 14.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 CEH12011.1 - 7.1 5.5 9.1 7.8 5.4 9.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Sporozoite_P67 PF05642.11 CEH12011.1 - 7.2 4.6 12.3 8.1 4.4 12.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Presenilin PF01080.17 CEH12011.1 - 8.4 5.0 14.4 9.8 4.8 14.4 1.0 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CEH12011.1 - 9.5 4.0 8.2 9.8 3.9 8.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 CEH12011.1 - 9.6 4.9 7.9 11 4.7 7.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter GMC_oxred_C PF05199.13 CEH12012.1 - 3.2e-14 53.7 0.0 3.2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase HSF_DNA-bind PF00447.17 CEH12013.1 - 3.8e-33 114.0 0.7 5e-33 113.6 0.7 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Cdc6_C PF09079.11 CEH12013.1 - 0.0064 16.4 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain Glycos_transf_2 PF00535.26 CEH12015.1 - 4.2e-29 101.5 0.0 6.7e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 CEH12015.1 - 1.6e-19 70.6 0.8 1.6e-19 70.6 0.8 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEH12015.1 - 3.7e-17 63.0 0.0 5.2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CEH12015.1 - 2.4e-15 56.4 0.0 3.8e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 CEH12015.1 - 1.1e-05 24.3 3.5 0.00051 18.7 1.0 2.9 2 1 1 3 3 3 1 Cellulose synthase UDPG_MGDP_dh_N PF03721.14 CEH12016.1 - 3.2e-58 196.4 0.0 7.5e-58 195.2 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 CEH12016.1 - 1.1e-26 92.8 0.0 2.4e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 CEH12016.1 - 1.7e-19 70.2 0.0 5e-15 55.8 0.0 2.6 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 CEH12016.1 - 0.0027 17.9 0.0 0.17 12.1 0.0 2.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 CEH12016.1 - 0.044 14.0 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 CEH12016.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AcetylCoA_hyd_C PF13336.6 CEH12017.1 - 0.043 13.8 0.0 0.055 13.4 0.0 1.1 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain EamA PF00892.20 CEH12020.1 - 1.9e-17 63.7 32.3 5.7e-11 42.7 14.2 2.5 3 0 0 3 3 3 2 EamA-like transporter family DUF2105 PF09878.9 CEH12020.1 - 0.019 14.7 1.5 0.035 13.8 1.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) DUF202 PF02656.15 CEH12020.1 - 8.5 6.9 10.9 22 5.6 0.4 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF202) Ras PF00071.22 CEH12021.1 - 1.3e-55 187.4 0.0 1.6e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH12021.1 - 8.1e-34 116.4 0.0 1.2e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH12021.1 - 3.7e-14 52.6 0.0 1.5e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEH12021.1 - 2.2e-05 23.9 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEH12021.1 - 0.00088 19.3 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEH12021.1 - 0.0012 18.4 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CEH12021.1 - 0.0013 19.2 0.2 0.0022 18.4 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain RRM_1 PF00076.22 CEH12023.1 - 4.2e-11 42.5 0.0 5.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEH12023.1 - 0.00078 19.5 0.1 0.0011 19.0 0.1 1.3 1 0 0 1 1 1 1 RNA binding motif COG5 PF10392.9 CEH12024.1 - 3.4e-12 46.7 6.5 1e-11 45.1 6.5 1.9 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Proteasome PF00227.26 CEH12025.1 - 1.3e-10 41.1 0.0 2.1e-10 40.4 0.0 1.3 1 1 0 1 1 1 1 Proteasome subunit DUF3989 PF13150.6 CEH12034.1 - 0.0086 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3989) Mur_ligase_M PF08245.12 CEH12036.1 - 0.00074 19.6 0.0 0.03 14.3 0.0 2.8 1 1 1 2 2 2 1 Mur ligase middle domain DUF3040 PF11239.8 CEH12036.1 - 0.11 12.7 0.5 0.28 11.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) RAP80_UIM PF18282.1 CEH12036.1 - 0.85 9.4 5.6 0.21 11.4 1.8 1.9 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif Ribosomal_60s PF00428.19 CEH12036.1 - 6.7 7.4 15.5 1.2 9.8 0.2 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein CLASP_N PF12348.8 CEH12037.1 - 5.6e-26 91.5 0.1 9.9e-26 90.7 0.1 1.3 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 CEH12037.1 - 0.83 10.1 8.9 0.24 11.8 1.3 4.3 5 0 0 5 5 5 0 HEAT repeat C2 PF00168.30 CEH12038.1 - 5.6e-25 87.6 0.0 6.7e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain Peroxidase_2 PF01328.17 CEH12039.1 - 1.9e-45 155.7 0.0 2.8e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 Pkinase PF00069.25 CEH12040.1 - 1.7e-64 217.8 0.0 2.3e-63 214.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH12040.1 - 2.7e-27 95.7 0.0 8.7e-21 74.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CEH12040.1 - 1.1e-07 31.1 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEH12040.1 - 0.0036 17.3 8.4 0.089 12.7 0.1 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CEH12040.1 - 0.01 15.2 0.1 0.12 11.7 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CEH12040.1 - 0.021 14.2 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEH12040.1 - 0.022 13.6 0.0 0.067 12.0 0.0 1.8 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CEH12040.1 - 0.089 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 CEH12040.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SPX PF03105.19 CEH12040.1 - 3.7 7.4 9.4 6.2 6.6 9.4 1.3 1 0 0 1 1 1 0 SPX domain ACBP PF00887.19 CEH12041.1 - 1.6e-16 60.3 0.0 2.4e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein DSPn PF14671.6 CEH12042.1 - 3.2e-33 115.2 0.0 2.4e-31 109.0 0.1 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CEH12042.1 - 5.6e-13 48.9 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEH12042.1 - 0.00011 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CEH12042.1 - 0.00079 19.6 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CEH12042.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family SUR7 PF06687.12 CEH12043.1 - 7.6e-11 42.0 8.6 4e-10 39.7 8.6 1.9 1 1 0 1 1 1 1 SUR7/PalI family DuoxA PF10204.9 CEH12043.1 - 0.0024 17.0 2.3 0.0024 17.0 2.3 1.6 2 0 0 2 2 2 1 Dual oxidase maturation factor Claudin_2 PF13903.6 CEH12043.1 - 0.004 16.9 5.0 0.0066 16.2 5.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 CEH12043.1 - 0.021 14.3 1.0 0.042 13.3 1.0 1.4 1 0 0 1 1 1 0 Clc-like MRAP PF15183.6 CEH12043.1 - 0.22 11.5 0.8 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF805 PF05656.14 CEH12043.1 - 5 7.6 8.6 0.6 10.6 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Tim17 PF02466.19 CEH12044.1 - 2.2e-07 31.3 7.5 3.4e-07 30.6 7.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Polysacc_synt_C PF14667.6 CEH12044.1 - 0.063 13.3 1.4 0.089 12.9 1.4 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Romo1 PF10247.9 CEH12044.1 - 8.2 6.9 11.8 0.47 10.9 2.4 2.8 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 CLU PF13236.6 CEH12045.1 - 5.5e-72 242.2 0.0 8.5e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CEH12045.1 - 6.3e-44 150.1 0.0 1.2e-43 149.2 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 CEH12045.1 - 7.3e-21 74.3 4.5 8.6e-09 35.6 0.0 4.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 CEH12045.1 - 2e-13 49.8 12.6 0.0027 17.5 0.1 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat CLU_N PF15044.6 CEH12045.1 - 1.6e-05 25.2 0.0 0.0001 22.6 0.0 2.4 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term 4HBT_3 PF13622.6 CEH12046.1 - 1.8e-39 136.5 0.1 2.7e-39 135.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CEH12046.1 - 0.00019 21.3 0.1 0.00036 20.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA thioesterase FA_desaturase PF00487.24 CEH12047.1 - 1.5e-24 87.2 20.0 3.3e-13 50.1 8.1 2.5 2 1 1 3 3 3 2 Fatty acid desaturase Popeye PF04831.13 CEH12047.1 - 0.57 10.3 2.6 0.66 10.1 1.0 1.9 2 0 0 2 2 2 0 Popeye protein conserved region Alpha-amylase PF00128.24 CEH12048.1 - 7.2e-21 75.1 0.1 5.1e-20 72.3 0.1 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 CEH12048.1 - 1.1e-06 27.2 0.0 0.12 10.5 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Alpha-amylase_C PF02806.18 CEH12048.1 - 1.6e-06 28.5 0.0 3.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain DUF1939 PF09154.10 CEH12048.1 - 0.00034 20.7 0.1 0.00089 19.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Pex14_N PF04695.13 CEH12049.1 - 9.8 6.8 15.0 0.59 10.8 0.2 3.7 3 1 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med7 PF05983.11 CEH12050.1 - 3.1e-36 125.3 0.4 3.1e-36 125.3 0.4 2.1 2 1 0 2 2 2 1 MED7 protein Cmc1 PF08583.10 CEH12051.1 - 4e-16 58.8 3.1 5.4e-16 58.4 3.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CEH12051.1 - 0.014 15.5 0.4 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 CHCH domain Pet191_N PF10203.9 CEH12051.1 - 0.021 15.1 0.4 6.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF1456 PF07308.13 CEH12051.1 - 0.15 12.4 0.3 0.29 11.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) COX17 PF05051.13 CEH12051.1 - 0.28 11.6 2.2 4.3 7.8 0.1 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Tom6 PF17112.5 CEH12052.1 - 0.18 11.3 1.9 0.26 10.8 1.9 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal Ribosomal_L4 PF00573.22 CEH12053.1 - 5.2e-60 202.4 0.0 7.8e-60 201.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Stathmin PF00836.19 CEH12054.1 - 4.3 7.3 18.3 29 4.6 18.8 2.1 2 1 0 2 2 2 0 Stathmin family adh_short PF00106.25 CEH12057.1 - 6.2e-26 91.1 2.0 2.2e-23 82.7 0.2 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEH12057.1 - 4.3e-20 72.3 4.7 1e-18 67.8 4.7 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH12057.1 - 1.8e-07 31.2 0.1 2.7e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF2201 PF09967.9 CEH12057.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 VWA-like domain (DUF2201) ABC_tran PF00005.27 CEH12058.1 - 4.3e-44 150.4 0.0 2.4e-25 89.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CEH12058.1 - 3e-33 115.7 24.1 3.2e-18 66.4 7.1 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 CEH12058.1 - 1.3e-06 28.0 0.0 0.018 14.5 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEH12058.1 - 0.002 17.9 0.4 1.4 8.7 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CEH12058.1 - 0.0039 17.5 0.3 3.9 7.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 CEH12058.1 - 0.0088 16.2 0.1 0.022 14.9 0.1 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_23 PF13476.6 CEH12058.1 - 0.017 15.6 8.7 0.044 14.3 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 CEH12058.1 - 0.048 13.5 0.8 35 4.1 0.1 3.9 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CEH12058.1 - 0.078 13.4 1.4 0.32 11.4 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain T2SSE PF00437.20 CEH12058.1 - 0.08 12.0 0.7 1.2 8.1 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_25 PF13481.6 CEH12058.1 - 0.094 12.3 0.4 15 5.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain NIF PF03031.18 CEH12059.1 - 4.6e-06 26.5 0.0 0.063 13.0 0.0 3.4 3 0 0 3 3 3 3 NLI interacting factor-like phosphatase Syntaxin-6_N PF09177.11 CEH12061.1 - 0.016 15.8 9.6 0.78 10.3 2.6 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Csm2_III-A PF03750.13 CEH12061.1 - 0.066 14.0 1.8 0.13 13.1 1.8 1.5 1 0 0 1 1 1 0 Csm2 Type III-A Exonuc_VII_L PF02601.15 CEH12061.1 - 0.14 11.7 6.9 0.27 10.7 6.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 CEH12061.1 - 0.14 12.4 8.8 0.11 12.8 2.0 2.7 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Golgin_A5 PF09787.9 CEH12061.1 - 0.15 11.5 14.6 0.28 10.6 14.6 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF573 PF04504.14 CEH12061.1 - 0.28 11.9 3.6 0.55 10.9 3.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF573 XhlA PF10779.9 CEH12061.1 - 0.36 11.1 4.3 0.23 11.7 0.9 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.12 CEH12061.1 - 0.37 10.8 8.9 0.77 9.8 5.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ALMS_motif PF15309.6 CEH12061.1 - 0.41 11.1 10.3 0.062 13.8 6.3 1.7 2 0 0 2 2 1 0 ALMS motif Baculo_PEP_C PF04513.12 CEH12061.1 - 0.43 10.6 4.1 1.3 9.1 3.9 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 CEH12061.1 - 0.48 10.6 7.1 0.94 9.7 7.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Sipho_Gp157 PF05565.11 CEH12061.1 - 0.52 10.3 6.1 0.93 9.5 6.1 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 RPN7 PF10602.9 CEH12061.1 - 1.8 8.3 4.7 2.9 7.6 4.7 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 OmpH PF03938.14 CEH12061.1 - 2.7 8.4 19.0 7.3 6.9 7.4 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Prominin PF05478.11 CEH12061.1 - 3 5.7 6.1 4.2 5.2 6.1 1.2 1 0 0 1 1 1 0 Prominin LMBR1 PF04791.16 CEH12061.1 - 3.3 6.5 9.9 4.8 6.0 9.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TolA_bind_tri PF16331.5 CEH12061.1 - 3.4 7.8 12.8 0.3 11.2 4.3 2.7 1 1 1 2 2 2 0 TolA binding protein trimerisation Nup88 PF10168.9 CEH12061.1 - 6.2 4.5 12.9 8.8 4.0 12.9 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF3584 PF12128.8 CEH12061.1 - 6.3 4.2 20.7 8.8 3.7 20.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec34 PF04136.15 CEH12061.1 - 8.1 6.3 11.8 4.5 7.1 4.8 2.3 1 1 1 2 2 2 0 Sec34-like family V_ATPase_I PF01496.19 CEH12061.1 - 8.4 4.2 11.6 1.6 6.6 4.1 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4404 PF14357.6 CEH12061.1 - 8.9 7.0 10.8 1.4 9.6 4.7 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) UDG PF03167.19 CEH12063.1 - 0.041 13.9 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily Csm1_N PF18504.1 CEH12063.1 - 0.081 13.3 5.2 7 7.1 0.4 3.8 3 0 0 3 3 3 0 Csm1 N-terminal domain YqjK PF13997.6 CEH12063.1 - 0.13 12.5 0.9 2.8 8.2 0.1 2.7 2 0 0 2 2 2 0 YqjK-like protein Spc7 PF08317.11 CEH12063.1 - 1.7 7.5 8.0 1.8 7.4 6.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Methyltransf_16 PF10294.9 CEH12066.1 - 9.3e-12 45.0 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 CEH12066.1 - 0.21 10.9 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RWD PF05773.22 CEH12067.1 - 1.8e-21 76.6 1.1 2.5e-21 76.1 0.1 1.8 2 1 0 2 2 2 1 RWD domain DFRP_C PF16543.5 CEH12067.1 - 0.0056 17.1 10.0 0.0056 17.1 10.0 2.9 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 UPF0183 PF03676.14 CEH12068.1 - 5e-23 82.0 0.0 4.7e-21 75.6 0.0 3.0 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) DSPc PF00782.20 CEH12069.1 - 6.2e-17 61.7 0.0 1.2e-13 51.0 0.0 2.7 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEH12069.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF4495 PF14906.6 CEH12070.1 - 0.037 13.1 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) Tup_N PF08581.10 CEH12070.1 - 0.14 12.5 0.4 0.34 11.2 0.1 1.9 1 1 1 2 2 2 0 Tup N-terminal DUF1664 PF07889.12 CEH12070.1 - 0.17 11.9 0.7 0.71 9.9 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Astro_capsid_p PF12226.8 CEH12071.1 - 0.074 12.2 0.1 0.099 11.8 0.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein THUMP PF02926.17 CEH12072.1 - 2.3e-11 44.0 0.0 4.2e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 THUMP domain GalKase_gal_bdg PF10509.9 CEH12073.1 - 1.4e-20 72.5 0.1 3.4e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CEH12073.1 - 2.2e-12 47.0 0.3 5.8e-12 45.7 0.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CEH12073.1 - 9.1e-12 45.2 0.0 2.6e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Glyco_hydro_43 PF04616.14 CEH12074.1 - 8.7e-10 38.4 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1794 PF08768.11 CEH12074.1 - 0.041 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1794) Frag1 PF10277.9 CEH12075.1 - 9.1e-27 94.0 11.6 2.3e-26 92.7 11.6 1.8 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family E1-E2_ATPase PF00122.20 CEH12075.1 - 1.6 8.2 3.5 1.4 8.4 1.3 2.0 2 0 0 2 2 2 0 E1-E2 ATPase Peptidase_S9 PF00326.21 CEH12076.1 - 4.5e-43 147.2 0.1 8.7e-43 146.3 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 CEH12076.1 - 0.0017 17.1 1.2 0.2 10.3 1.2 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 CEH12076.1 - 0.0097 15.6 0.4 0.084 12.5 0.4 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold DPPIV_N PF00930.21 CEH12076.1 - 0.061 12.1 0.0 0.52 9.0 0.0 2.0 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_1 PF00561.20 CEH12077.1 - 3.3e-15 56.4 0.0 1.1e-12 48.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH12077.1 - 1.7e-14 54.9 0.0 2.2e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH12077.1 - 3.5e-14 52.7 0.0 7.7e-14 51.5 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CEH12077.1 - 6.6e-05 22.8 0.0 0.071 12.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.18 CEH12077.1 - 0.0031 17.1 0.7 0.72 9.4 0.2 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Thioesterase PF00975.20 CEH12077.1 - 0.0085 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 CEH12077.1 - 0.013 14.9 0.2 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 CEH12077.1 - 0.046 13.4 0.2 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.20 CEH12077.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative esterase DUF2920 PF11144.8 CEH12077.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) MOZ_SAS PF01853.18 CEH12078.1 - 1.3e-55 187.9 0.0 4.3e-55 186.1 0.0 1.7 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 CEH12078.1 - 1.5e-14 53.3 1.1 3.5e-06 26.5 0.3 2.4 2 0 0 2 2 2 2 MYST family zinc finger domain BPL_LplA_LipB PF03099.19 CEH12079.1 - 2e-05 24.5 0.0 4.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF3818 PF12825.7 CEH12080.1 - 1.2e-124 415.8 0.0 1.6e-124 415.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CEH12080.1 - 3.3e-38 130.6 0.2 6.4e-38 129.7 0.2 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 CEH12080.1 - 3e-06 27.2 0.0 2.1e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 PX domain Nop14 PF04147.12 CEH12080.1 - 0.12 10.6 5.1 0.17 10.1 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.6 CEH12080.1 - 0.98 9.7 7.9 37 4.6 6.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 CEH12080.1 - 1.1 7.5 6.5 1.7 6.9 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 CEH12080.1 - 1.5 8.1 11.1 3.2 7.0 11.1 1.5 1 0 0 1 1 1 0 BUD22 Apt1 PF10351.9 CEH12080.1 - 7.6 5.3 9.3 19 4.0 9.3 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pro_isomerase PF00160.21 CEH12081.1 - 1.7e-30 106.4 0.0 7.3e-29 101.1 0.0 2.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CEH12081.1 - 5.8e-12 45.2 0.0 1.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med6 PF04934.14 CEH12082.1 - 4.7e-30 104.1 0.0 6.4e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Pal1 PF08316.11 CEH12083.1 - 2.1e-17 64.1 0.3 2.1e-17 64.1 0.3 2.6 3 0 0 3 3 3 1 Pal1 cell morphology protein Mito_fiss_reg PF05308.11 CEH12083.1 - 0.4 10.7 3.6 1.7 8.7 3.6 2.1 1 1 0 1 1 1 0 Mitochondrial fission regulator Memo PF01875.17 CEH12086.1 - 1.7e-66 224.1 0.0 2.9e-64 216.8 0.0 2.7 1 1 0 1 1 1 1 Memo-like protein Pox_RNA_Pol_19 PF05320.12 CEH12086.1 - 0.21 11.5 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Acyl-CoA_dh_1 PF00441.24 CEH12087.1 - 1.2e-16 61.3 2.4 1.1e-15 58.2 2.4 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEH12087.1 - 1.8e-14 53.7 0.2 2.9e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CEH12087.1 - 3.3e-10 40.6 0.1 1.1e-09 38.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CEH12087.1 - 1.5e-06 28.5 0.2 2.4e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MerR-DNA-bind PF09278.11 CEH12088.1 - 0.058 13.9 0.2 0.058 13.9 0.2 3.0 3 0 0 3 3 3 0 MerR, DNA binding SET PF00856.28 CEH12090.1 - 3.7e-10 40.5 0.0 1.8e-09 38.2 0.0 2.2 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 CEH12090.1 - 1.7e-09 37.6 15.0 1.7e-09 37.6 15.0 2.9 3 0 0 3 3 3 1 MYND finger Sugar_tr PF00083.24 CEH12091.1 - 4.1e-87 292.9 22.0 4.8e-87 292.7 22.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH12091.1 - 1.5e-15 57.0 42.7 2e-12 46.7 29.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily YdaS_antitoxin PF15943.5 CEH12092.1 - 0.021 14.7 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT adh_short PF00106.25 CEH12093.1 - 2.3e-38 131.6 0.4 5.3e-38 130.4 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH12093.1 - 9.3e-38 130.1 0.8 4e-37 128.0 0.8 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH12093.1 - 6.6e-10 39.2 1.5 6.6e-10 39.2 1.5 1.6 2 0 0 2 2 2 1 KR domain AlaDh_PNT_C PF01262.21 CEH12093.1 - 0.013 14.8 2.4 0.025 13.9 2.4 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SNF2_N PF00176.23 CEH12094.1 - 1.3e-54 185.3 0.1 2.4e-46 158.1 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CEH12094.1 - 3.7e-17 62.7 0.1 2.8e-15 56.6 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 CEH12094.1 - 1.9e-07 30.9 8.8 1.9e-07 30.9 8.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 CEH12094.1 - 1.2e-06 28.6 0.0 2.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 CEH12094.1 - 1.1e-05 25.1 7.5 2.8e-05 23.9 7.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CEH12094.1 - 1.3e-05 25.0 7.5 1.3e-05 25.0 7.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CEH12094.1 - 0.0001 22.1 0.1 0.00027 20.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 CEH12094.1 - 0.00041 20.1 8.1 0.00041 20.1 8.1 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEH12094.1 - 0.00054 20.2 9.6 0.00054 20.2 9.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CEH12094.1 - 0.0016 18.5 6.8 0.0016 18.5 6.8 2.2 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEH12094.1 - 0.0026 17.7 9.6 0.0026 17.7 9.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 CEH12094.1 - 0.025 14.6 11.9 0.71 9.9 0.8 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_6 PF14835.6 CEH12094.1 - 0.59 10.0 3.4 1.2 9.0 3.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ketoacyl-synt PF00109.26 CEH12095.1 - 1.2e-27 97.1 1.0 2.2e-27 96.2 1.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CEH12095.1 - 8.5e-17 61.3 1.7 9.7e-17 61.1 0.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 CEH12095.1 - 2.7e-14 53.3 0.0 5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Thiolase_N PF00108.23 CEH12095.1 - 0.0014 18.1 1.0 0.0036 16.7 0.6 1.8 1 1 1 2 2 2 1 Thiolase, N-terminal domain DUF1729 PF08354.10 CEH12097.1 - 3e-65 220.5 0.1 5.1e-65 219.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) SAT PF16073.5 CEH12097.1 - 7.3e-36 124.1 0.3 1.5e-35 123.1 0.0 1.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 CEH12097.1 - 9.1e-05 22.5 1.8 0.0011 18.9 0.2 3.1 2 1 1 3 3 3 1 N-terminal domain in fatty acid synthase subunit beta Pkinase PF00069.25 CEH12098.1 - 1.7e-47 162.0 0.0 2.6e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH12098.1 - 5.4e-24 84.9 0.0 9.2e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CEH12098.1 - 0.0035 16.4 0.1 0.0054 15.8 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CEH12098.1 - 0.049 12.4 0.0 0.082 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CEH12098.1 - 0.054 13.4 0.1 0.3 11.0 0.1 2.3 1 1 2 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 CEH12098.1 - 0.11 12.1 0.6 0.91 9.1 0.1 2.2 1 1 1 2 2 2 0 RIO1 family CUE PF02845.16 CEH12099.1 - 3.1e-12 46.0 0.0 5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 CEH12099.1 - 0.062 13.3 1.8 0.11 12.6 1.8 1.3 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 G2BR PF18442.1 CEH12099.1 - 0.39 10.4 6.4 0.67 9.6 6.4 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) DPBB_1 PF03330.18 CEH12100.1 - 2.3e-07 31.0 0.1 5.2e-07 29.8 0.1 1.7 1 1 0 1 1 1 1 Lytic transglycolase zf-NF-X1 PF01422.17 CEH12100.1 - 3.4 7.8 6.8 21 5.3 6.5 2.3 1 1 1 2 2 2 0 NF-X1 type zinc finger MAS20 PF02064.15 CEH12101.1 - 9.6e-39 132.4 0.2 1.4e-38 131.9 0.2 1.3 1 0 0 1 1 1 1 MAS20 protein import receptor WD40 PF00400.32 CEH12102.1 - 1.4e-32 111.1 11.1 4.1e-05 24.3 0.1 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 CEH12102.1 - 7.5e-10 38.6 4.7 1.7e-09 37.4 0.8 2.4 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.8 CEH12102.1 - 4.5e-05 22.3 0.8 0.61 8.7 0.1 3.2 3 0 0 3 3 3 3 Nucleoporin Nup120/160 F-box PF00646.33 CEH12102.1 - 0.00041 20.1 1.7 0.00051 19.8 0.2 1.9 2 0 0 2 2 2 1 F-box domain DUF2040 PF09745.9 CEH12103.1 - 7.2e-29 100.3 19.0 7.2e-29 100.3 19.0 1.7 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF1287 PF06940.11 CEH12103.1 - 0.03 14.0 0.2 0.046 13.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) DDE_3 PF13358.6 CEH12104.1 - 1.8e-15 57.0 0.0 3.2e-15 56.1 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEH12104.1 - 0.031 14.5 1.9 0.041 14.1 0.3 2.0 2 0 0 2 2 2 0 Transposase LSM PF01423.22 CEH12108.1 - 8e-19 67.1 0.3 1.1e-18 66.7 0.3 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CEH12108.1 - 0.019 14.6 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 Hfq protein Prefoldin_2 PF01920.20 CEH12110.1 - 1.3e-11 44.4 9.6 5.3e-07 29.5 0.7 2.2 1 1 1 2 2 2 2 Prefoldin subunit DUF4600 PF15372.6 CEH12110.1 - 0.0027 18.1 3.4 1.1 9.7 0.7 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4600) Seryl_tRNA_N PF02403.22 CEH12110.1 - 0.0045 17.2 11.0 0.068 13.4 4.8 2.1 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 CEH12110.1 - 0.0065 16.2 10.4 0.77 9.6 6.8 2.7 2 1 0 2 2 2 2 Septum formation initiator Spc24 PF08286.11 CEH12110.1 - 0.009 16.2 8.5 0.27 11.5 3.2 2.4 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 VP4_helical PF17478.2 CEH12110.1 - 0.13 11.7 0.7 0.19 11.1 0.7 1.3 1 0 0 1 1 1 0 Rotavirus VP4 helical domain Mod_r PF07200.13 CEH12110.1 - 0.19 11.9 8.5 1.5 8.9 0.1 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PI3K_P85_iSH2 PF16454.5 CEH12110.1 - 0.3 10.7 7.3 2.1 8.0 0.4 2.2 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DASH_Dad3 PF08656.10 CEH12110.1 - 0.31 11.2 3.2 6.1 7.0 0.9 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 FlaC_arch PF05377.11 CEH12110.1 - 0.4 11.1 3.4 1.3 9.5 0.6 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ax_dynein_light PF10211.9 CEH12110.1 - 0.44 10.5 7.6 1.3 8.9 2.6 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain ZapB PF06005.12 CEH12110.1 - 0.66 10.5 11.4 5.8 7.4 0.3 2.5 2 1 0 2 2 2 0 Cell division protein ZapB JIP_LZII PF16471.5 CEH12110.1 - 0.92 9.7 11.4 4.1 7.6 2.1 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 CEH12110.1 - 1.1 9.7 19.7 5.9 7.4 10.7 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4140 PF13600.6 CEH12110.1 - 2.8 8.4 9.0 1.4 9.4 1.9 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CEP209_CC5 PF16574.5 CEH12110.1 - 4.9 7.3 12.5 5 7.3 4.2 2.3 2 1 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 bZIP_1 PF00170.21 CEH12110.1 - 8.8 6.5 11.4 4.7 7.4 3.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor Thiamine_BP PF01910.17 CEH12111.1 - 1.9e-22 79.0 0.0 2.7e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Thiamine-binding protein SNF2_N PF00176.23 CEH12112.1 - 6.9e-33 113.8 0.0 2.1e-32 112.2 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 CEH12112.1 - 6.4e-08 32.3 9.8 1.2e-07 31.4 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEH12112.1 - 0.00016 21.4 9.9 0.00035 20.4 9.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.31 CEH12112.1 - 0.00026 21.3 0.0 0.00051 20.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 CEH12112.1 - 0.00032 20.5 10.3 0.00079 19.2 10.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEH12112.1 - 0.0015 18.8 10.4 0.0015 18.8 10.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CEH12112.1 - 0.0017 18.3 8.9 0.0041 17.0 8.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.20 CEH12112.1 - 0.11 12.2 1.1 0.25 11.1 1.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.6 CEH12112.1 - 0.21 11.4 7.6 0.53 10.1 7.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 CEH12112.1 - 8.1 6.6 16.1 0.042 13.9 5.3 2.8 2 1 1 3 3 3 0 RING-type zinc-finger CS PF04969.16 CEH12113.1 - 2.4e-16 60.5 0.6 3.7e-16 59.9 0.6 1.3 1 0 0 1 1 1 1 CS domain FKBP_C PF00254.28 CEH12114.1 - 3.5e-34 117.0 0.0 4e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF1_GNE PF00736.19 CEH12115.1 - 9.2e-31 105.9 0.8 9.2e-31 105.9 0.8 2.0 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CEH12115.1 - 2.9e-13 50.0 5.0 2.9e-13 50.0 5.0 3.0 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 CEH12115.1 - 0.041 14.1 0.4 0.84 9.9 0.0 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Bystin PF05291.11 CEH12116.1 - 2.6e-120 401.2 0.0 3.5e-120 400.7 0.0 1.1 1 0 0 1 1 1 1 Bystin RasGAP PF00616.19 CEH12117.1 - 1.9e-58 197.6 0.0 4.8e-58 196.3 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 CEH12117.1 - 1.2e-37 129.1 0.1 4e-37 127.4 0.1 2.0 1 0 0 1 1 1 1 RasGAP C-terminus YabA PF06156.13 CEH12117.1 - 0.63 10.7 5.2 24 5.6 0.0 3.6 3 0 0 3 3 3 0 Initiation control protein YabA Pkinase PF00069.25 CEH12118.1 - 6.9e-64 215.7 0.0 8.8e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH12118.1 - 5.9e-39 133.9 0.0 1.1e-38 133.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH12118.1 - 0.00026 20.4 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEH12118.1 - 0.0022 16.8 0.2 0.0047 15.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase ASH PF15780.5 CEH12119.1 - 3.9e-12 46.2 3.6 0.011 16.0 0.1 6.9 8 0 0 8 8 8 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CEH12119.1 - 2.5e-09 37.2 0.2 0.84 9.8 0.1 5.5 5 0 0 5 5 5 3 Flagellar-associated PapD-like TMEM131_like PF12371.8 CEH12119.1 - 2.4e-05 24.5 0.7 0.61 10.4 0.0 5.4 4 1 1 5 5 5 2 Transmembrane protein 131-like DUF1090 PF06476.12 CEH12119.1 - 0.21 11.7 2.5 0.61 10.2 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) PUF PF00806.19 CEH12120.1 - 7.5e-10 37.9 0.0 0.69 9.7 0.0 6.1 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat SurE PF01975.17 CEH12121.1 - 1.3e-25 90.3 0.4 2.8e-25 89.2 0.4 1.6 1 1 0 1 1 1 1 Survival protein SurE PBP PF01161.20 CEH12123.1 - 5.4e-05 23.5 0.0 8.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Na_H_Exchanger PF00999.21 CEH12125.1 - 3.2e-44 151.3 21.8 4.2e-44 150.9 21.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF308 PF03729.13 CEH12125.1 - 0.03 14.7 9.1 1.2 9.5 2.7 3.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Med11 PF10280.9 CEH12126.1 - 0.00013 22.5 0.2 0.00029 21.3 0.2 1.7 1 1 0 1 1 1 1 Mediator complex protein FliT PF05400.13 CEH12126.1 - 4 8.3 9.9 0.41 11.5 3.7 2.4 2 0 0 2 2 2 0 Flagellar protein FliT Peptidase_S8 PF00082.22 CEH12128.1 - 1e-41 143.1 0.5 2.1e-41 142.1 0.5 1.6 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CEH12128.1 - 9.1e-09 36.0 0.3 5.2e-08 33.6 0.3 2.3 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 CEH12128.1 - 1.6e-05 24.8 0.0 5.1e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 PA domain Spt46 PF17734.1 CEH12129.1 - 0.1 12.4 0.4 5.3 6.8 0.1 2.0 1 1 1 2 2 2 0 Spermatogenesis-associated protein 46 Pkinase PF00069.25 CEH12130.1 - 3.3e-43 148.0 0.0 1.1e-41 143.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH12130.1 - 2.4e-13 50.0 0.0 4.5e-12 45.8 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH12130.1 - 0.0011 17.8 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEH12130.1 - 0.0049 16.8 0.5 0.09 12.7 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CEH12130.1 - 0.0057 16.0 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ytp1 PF10355.9 CEH12131.1 - 3.7e-56 190.4 10.9 3.5e-54 183.9 10.9 2.6 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CEH12131.1 - 6e-23 80.6 0.4 6e-23 80.6 0.4 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) EMC3_TMCO1 PF01956.16 CEH12131.1 - 0.8 9.4 2.2 2 8.2 0.0 2.6 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like Mg_trans_NIPA PF05653.14 CEH12132.1 - 7.6e-24 84.3 6.8 1.7e-12 47.1 2.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 CEH12132.1 - 0.31 11.2 17.9 1.4 9.1 5.2 2.5 2 0 0 2 2 2 0 EamA-like transporter family ILVD_EDD PF00920.21 CEH12133.1 - 1.4e-195 650.8 4.1 1.6e-195 650.6 4.1 1.0 1 0 0 1 1 1 1 Dehydratase family Kinesin PF00225.23 CEH12134.1 - 2.2e-103 345.7 0.4 6.8e-103 344.1 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEH12134.1 - 8.5e-25 87.4 0.0 2.7e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding PspB PF06667.12 CEH12134.1 - 0.093 12.8 3.4 1.4 9.0 0.1 3.4 2 0 0 2 2 2 0 Phage shock protein B CAP_GLY PF01302.25 CEH12136.1 - 2.2e-17 62.8 0.3 2.1e-16 59.7 0.0 2.3 2 0 0 2 2 2 1 CAP-Gly domain LRR_8 PF13855.6 CEH12136.1 - 4.5e-12 45.6 8.3 3.4e-06 26.7 0.8 5.5 5 1 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 CEH12136.1 - 4.7e-11 42.7 8.4 0.00022 21.5 0.0 5.1 3 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEH12136.1 - 8.7e-06 25.3 0.0 0.0028 17.2 0.0 3.2 3 1 1 4 4 4 1 Leucine-rich repeat LRR_6 PF13516.6 CEH12136.1 - 0.00011 22.0 3.9 0.7 10.1 0.2 5.4 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 CEH12136.1 - 0.011 16.2 7.1 40 5.3 0.4 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat Thioredoxin PF00085.20 CEH12137.1 - 0.044 13.8 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin DivIC PF04977.15 CEH12140.1 - 4.4 7.1 9.7 0.27 11.0 1.9 2.3 2 1 0 2 2 2 0 Septum formation initiator DUF987 PF06174.11 CEH12141.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF987) OmdA PF13376.6 CEH12142.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DEAD_2 PF06733.15 CEH12142.1 - 0.17 11.5 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 DEAD_2 MIF4G PF02854.19 CEH12145.1 - 1.7e-51 174.9 0.0 1.1e-31 110.2 0.0 3.2 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 CEH12145.1 - 1.4e-29 103.6 1.8 1.4e-29 103.6 1.8 2.5 3 0 0 3 3 3 1 Up-frameshift suppressor 2 RNase_PH PF01138.21 CEH12146.1 - 1.8e-09 38.2 0.0 3.8e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Glyco_hydro_cc PF11790.8 CEH12147.1 - 6.3e-45 153.6 0.0 7.7e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF2851 PF11013.8 CEH12147.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) DEAD PF00270.29 CEH12148.1 - 1.1e-40 139.3 0.0 1.6e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH12148.1 - 3.6e-23 82.0 0.0 2.7e-22 79.2 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH12148.1 - 1.5e-06 28.3 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SIS_2 PF13580.6 CEH12149.1 - 3.1e-13 49.9 0.0 5.8e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 CEH12149.1 - 2e-08 34.1 1.9 4.2e-07 29.9 0.0 3.0 3 0 0 3 3 3 1 SIS domain UDG PF03167.19 CEH12151.1 - 2.9e-15 56.6 0.0 4.9e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PGC7_Stella PF15549.6 CEH12152.1 - 1.1 9.2 7.4 0.11 12.4 2.5 1.8 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain HD PF01966.22 CEH12153.1 - 8.4e-05 22.8 0.1 0.00023 21.4 0.1 1.7 1 1 0 1 1 1 1 HD domain Di19_C PF14571.6 CEH12153.1 - 0.042 14.4 0.3 0.076 13.6 0.0 1.5 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal RhoGAP PF00620.27 CEH12154.1 - 9.2e-35 119.7 0.0 1.5e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RNB PF00773.19 CEH12155.1 - 7.1e-99 331.2 0.0 1e-98 330.7 0.0 1.3 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 CEH12155.1 - 6.9e-22 77.6 0.0 1.4e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 CEH12155.1 - 7.8e-22 77.1 0.0 1.6e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CEH12155.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain DUF1326 PF07040.11 CEH12155.1 - 0.17 11.9 0.2 0.53 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) SMG1_N PF17229.2 CEH12156.1 - 0.059 14.1 0.1 0.22 12.3 0.0 2.0 2 0 0 2 2 2 0 Serine/threonine-protein kinase SMG1 N-terminal KAAG1 PF15354.6 CEH12156.1 - 0.063 13.8 0.5 0.21 12.2 0.5 1.9 1 0 0 1 1 1 0 Kidney-associated antigen 1 Val_tRNA-synt_C PF10458.9 CEH12156.1 - 0.11 12.9 0.2 0.22 11.8 0.2 1.5 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Glyco_hydro_3_C PF01915.22 CEH12157.1 - 1.3e-44 152.7 0.8 2.1e-44 151.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CEH12157.1 - 6.4e-43 147.3 0.0 1.1e-42 146.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CEH12157.1 - 1e-20 73.6 0.0 2.4e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF448 PF04296.13 CEH12158.1 - 0.037 13.9 0.3 5.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF448) NP1-WLL PF11733.8 CEH12158.1 - 0.31 10.8 3.9 0.42 10.3 3.4 1.4 1 1 0 1 1 1 0 Non-capsid protein NP1 tRNA-synt_2d PF01409.20 CEH12159.1 - 1.5e-85 286.6 0.0 2.1e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 CEH12159.1 - 8.5e-13 48.4 0.1 8.5e-13 48.4 0.1 2.1 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 CEH12159.1 - 4.1e-08 32.9 0.0 0.00019 20.9 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 CEH12159.1 - 3.6e-05 23.0 0.9 0.0013 17.9 0.0 2.9 2 1 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 CEH12159.1 - 0.00022 21.1 0.7 0.00045 20.2 0.1 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 CEH12159.1 - 0.019 14.9 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) zf-TFIIIC PF12660.7 CEH12160.1 - 1.4e-09 37.8 1.7 3.4e-09 36.6 1.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 CEH12160.1 - 6.1e-07 29.5 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Uso1_p115_head PF04869.14 CEH12162.1 - 1.8e-58 198.2 0.0 5.1e-58 196.6 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 CEH12162.1 - 9.4e-06 26.0 44.1 9.4e-06 26.0 44.1 3.4 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region DDHD PF02862.17 CEH12163.1 - 3.1e-32 112.6 0.8 2.8e-29 102.9 0.0 3.3 3 0 0 3 3 3 2 DDHD domain WWE PF02825.20 CEH12163.1 - 1.3e-05 25.7 2.9 0.015 15.9 0.7 2.9 2 0 0 2 2 2 2 WWE domain DUF1358 PF07096.11 CEH12163.1 - 0.15 12.1 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) PAP2_3 PF14378.6 CEH12164.1 - 4.2e-19 69.0 20.3 4.2e-19 69.0 20.3 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CEH12164.1 - 1.4e-09 37.8 6.4 1.4e-09 37.8 6.4 2.7 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CEH12164.1 - 0.0064 17.0 5.2 0.014 15.9 4.5 2.0 2 0 0 2 2 2 1 PAP2 superfamily C-terminal Na_Ca_ex PF01699.24 CEH12165.1 - 1.4e-41 142.0 33.2 7.2e-21 74.7 11.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF485 PF04341.12 CEH12165.1 - 0.11 12.5 0.1 0.11 12.5 0.1 3.8 4 2 0 4 4 4 0 Protein of unknown function, DUF485 GATA PF00320.27 CEH12166.1 - 3.3e-13 49.0 3.5 6.4e-13 48.1 3.5 1.5 1 0 0 1 1 1 1 GATA zinc finger SEP PF08059.13 CEH12167.1 - 2.3e-23 82.6 0.0 4.1e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CEH12167.1 - 9.6e-18 64.2 0.0 1.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CEH12167.1 - 3.6e-13 49.1 0.4 6.4e-13 48.3 0.4 1.4 1 0 0 1 1 1 1 UBA-like domain Hydrolase_4 PF12146.8 CEH12169.1 - 0.037 13.3 0.9 3.7 6.7 0.9 2.7 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH12169.1 - 0.075 12.7 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 CEH12170.1 - 6.2e-25 88.0 0.0 8.4e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CEH12170.1 - 3.6e-06 26.8 0.0 0.012 15.3 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH12170.1 - 0.055 12.7 0.0 0.79 8.9 0.0 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Pkinase PF00069.25 CEH12171.1 - 3.8e-10 39.6 0.0 5.8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CEH12171.1 - 0.00037 20.5 0.0 0.0011 19.0 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEH12171.1 - 0.0071 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CEH12171.1 - 0.044 12.8 0.0 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 CEH12171.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EbsA PF17255.2 CEH12173.1 - 0.32 11.3 1.9 0.54 10.6 0.5 2.0 2 0 0 2 2 2 0 EbsA-like protein RRM_1 PF00076.22 CEH12174.1 - 5.6e-14 51.7 0.0 9.5e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CEH12174.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain RRM_occluded PF16842.5 CEH12174.1 - 0.15 11.9 0.1 1.7 8.5 0.0 2.4 2 1 0 2 2 2 0 Occluded RNA-recognition motif AA_permease_2 PF13520.6 CEH12175.1 - 1.1e-33 116.7 39.1 1.4e-33 116.4 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease CusF_Ec PF11604.8 CEH12176.1 - 0.12 12.4 0.6 10 6.2 0.1 2.5 2 0 0 2 2 2 0 Copper binding periplasmic protein CusF DUF99 PF01949.16 CEH12176.1 - 0.18 11.2 0.9 0.38 10.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 CAF1 PF04857.20 CEH12177.1 - 2.1e-22 79.7 0.0 1e-11 44.6 0.0 2.5 2 1 0 2 2 2 2 CAF1 family ribonuclease Phage_sheath_1 PF04984.14 CEH12177.1 - 0.031 14.2 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain Alpha_GJ PF03229.13 CEH12177.1 - 0.33 11.5 8.5 0.53 10.8 8.5 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J Mito_carr PF00153.27 CEH12180.1 - 7.6e-66 218.1 4.4 1.6e-23 82.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tam41_Mmp37 PF09139.11 CEH12181.1 - 1.4e-112 376.3 0.0 1.7e-112 376.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial AAA_33 PF13671.6 CEH12182.1 - 1.8e-18 67.0 3.1 3.6e-16 59.6 1.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEH12182.1 - 0.00019 22.0 2.0 0.022 15.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEH12182.1 - 0.00048 20.5 1.4 0.0018 18.7 1.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 CEH12182.1 - 0.0032 16.8 0.2 0.058 12.7 0.0 2.2 2 1 1 3 3 3 2 Zeta toxin KTI12 PF08433.10 CEH12182.1 - 0.0047 16.4 2.4 0.73 9.2 1.9 2.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 CEH12182.1 - 0.005 17.1 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CEH12182.1 - 0.052 14.1 0.0 0.073 13.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter CobU PF02283.16 CEH12182.1 - 0.1 12.1 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase NACHT PF05729.12 CEH12182.1 - 0.11 12.5 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain GRIM-19 PF06212.12 CEH12183.1 - 3e-32 111.3 0.0 3.5e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein ACBP PF00887.19 CEH12186.1 - 1.2e-28 99.2 0.0 1.5e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein DUF1889 PF08986.10 CEH12186.1 - 0.02 15.3 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) Kelch_5 PF13854.6 CEH12187.1 - 2.5e-11 43.3 0.3 0.033 14.2 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CEH12187.1 - 1.7e-09 37.6 0.5 0.49 10.8 0.0 5.1 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 CEH12187.1 - 1.3e-07 31.5 1.5 0.01 15.8 0.1 5.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CEH12187.1 - 0.00029 21.0 0.6 0.00029 21.0 0.6 6.2 6 1 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CEH12187.1 - 0.00029 20.7 0.0 12 6.0 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 CEH12187.1 - 0.028 14.0 0.0 8.8 6.0 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Metallophos PF00149.28 CEH12188.1 - 5.3e-06 27.1 1.3 1.1e-05 26.0 1.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Clat_adaptor_s PF01217.20 CEH12189.1 - 3.9e-54 182.4 0.1 4.6e-54 182.2 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GTP_EFTU PF00009.27 CEH12190.1 - 2.3e-52 177.4 0.1 3.4e-52 176.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEH12190.1 - 4.1e-41 139.8 0.0 8.4e-41 138.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEH12190.1 - 1.4e-14 54.2 0.4 1.4e-14 54.2 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEH12190.1 - 0.002 18.2 0.1 0.069 13.2 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CEH12190.1 - 0.011 15.5 0.1 14 5.5 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain GTP_EFTU_D4 PF14578.6 CEH12190.1 - 0.019 14.9 0.2 0.063 13.2 0.2 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 NIF3 PF01784.18 CEH12190.1 - 0.05 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) LETM1 PF07766.13 CEH12193.1 - 6.5e-19 68.3 0.0 9.6e-10 38.2 0.0 2.2 1 1 1 2 2 2 2 LETM1-like protein Peptidase_M41 PF01434.18 CEH12194.1 - 7.5e-66 221.6 0.3 7.5e-66 221.6 0.3 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CEH12194.1 - 1.6e-43 148.3 0.0 7.7e-43 146.1 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 CEH12194.1 - 7.4e-13 48.8 0.0 1.9e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_lid_3 PF17862.1 CEH12194.1 - 2.9e-11 43.0 0.2 8.3e-11 41.5 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 CEH12194.1 - 0.0039 16.5 0.0 0.0064 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CEH12194.1 - 0.0053 16.8 0.2 0.094 12.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEH12194.1 - 0.0097 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEH12194.1 - 0.019 15.2 4.0 0.82 9.9 0.1 3.5 3 1 1 4 4 4 0 AAA domain AAA_2 PF07724.14 CEH12194.1 - 0.03 14.4 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CEH12194.1 - 0.036 14.4 4.5 0.053 13.9 0.1 3.4 3 1 0 3 3 3 0 AAA ATPase domain AAA_17 PF13207.6 CEH12194.1 - 0.07 13.6 0.0 0.07 13.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CEH12194.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein UPF0172 PF03665.13 CEH12194.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Mg_chelatase PF01078.21 CEH12194.1 - 0.15 11.4 0.2 0.58 9.5 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Aminotran_1_2 PF00155.21 CEH12195.1 - 8.8e-34 117.2 0.0 2.4e-33 115.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEH12195.1 - 0.00026 19.6 0.0 0.00074 18.2 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CEH12195.1 - 0.0039 16.5 0.0 0.018 14.3 0.0 1.9 2 0 0 2 2 2 1 Beta-eliminating lyase 2OG-FeII_Oxy_5 PF13759.6 CEH12195.1 - 0.12 12.8 0.1 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase HABP4_PAI-RBP1 PF04774.15 CEH12196.1 - 3.9e-12 47.0 0.6 3.9e-12 47.0 0.6 3.0 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Caprin-1_C PF12287.8 CEH12196.1 - 6.3 6.9 9.7 0.041 14.0 0.9 1.8 2 0 0 2 2 2 0 Cytoplasmic activation/proliferation-associated protein-1 C term Mito_carr PF00153.27 CEH12197.1 - 4.8e-43 145.0 8.5 4e-16 58.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-CHY PF05495.12 CEH12198.1 - 5.5e-14 52.4 11.6 1.1e-13 51.4 11.6 1.5 1 1 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.6 CEH12198.1 - 3.6e-05 23.5 4.2 0.0058 16.4 1.2 2.4 1 1 1 2 2 2 2 Cysteine-rich KTR zinc_ribbon_9 PF14369.6 CEH12198.1 - 0.0085 16.3 2.1 0.0085 16.3 2.1 2.8 2 1 0 2 2 2 1 zinc-ribbon zf-FPG_IleRS PF06827.14 CEH12198.1 - 0.0099 15.7 1.5 0.044 13.6 1.5 2.1 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Trm112p PF03966.16 CEH12198.1 - 0.014 16.0 2.4 0.11 13.0 0.6 2.6 2 1 0 2 2 2 0 Trm112p-like protein Elf1 PF05129.13 CEH12198.1 - 0.037 14.1 9.5 0.037 14.1 4.2 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 CEH12198.1 - 0.061 13.2 2.0 0.061 13.2 2.0 3.7 2 2 2 4 4 4 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CEH12198.1 - 0.32 10.9 0.2 0.32 10.9 0.2 2.9 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DUF3797 PF12677.7 CEH12198.1 - 0.5 10.3 0.2 0.5 10.3 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) Zn-ribbon_8 PF09723.10 CEH12198.1 - 1.1 9.5 12.9 0.17 12.0 2.5 2.8 1 1 1 2 2 2 0 Zinc ribbon domain C1_4 PF07975.12 CEH12198.1 - 2.3 8.5 8.8 13 6.1 4.1 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain zf-DBF PF07535.12 CEH12198.1 - 4.3 7.5 9.1 3.8 7.7 1.6 3.1 3 0 0 3 3 3 0 DBF zinc finger zf-C2HC_2 PF13913.6 CEH12198.1 - 4.6 7.3 9.2 0.9 9.5 0.2 2.7 3 0 0 3 3 2 0 zinc-finger of a C2HC-type LIP PF03583.14 CEH12199.1 - 8.7e-56 189.3 0.0 1.3e-55 188.8 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Piwi PF02171.17 CEH12201.1 - 5.1e-71 239.4 0.0 6.7e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CEH12201.1 - 7.3e-15 55.8 0.0 2.3e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CEH12201.1 - 2.7e-13 49.3 0.1 8e-13 47.8 0.1 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 CEH12201.1 - 2.9e-12 46.6 0.0 8.2e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 PAZ domain ArgoMid PF16487.5 CEH12201.1 - 1.6e-06 28.3 0.0 3.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 CEH12201.1 - 6.6e-06 26.4 0.0 1.6e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain Metal_resist PF13801.6 CEH12201.1 - 0.055 13.7 4.4 0.079 13.2 2.1 2.5 2 0 0 2 2 2 0 Heavy-metal resistance PHD PF00628.29 CEH12203.1 - 1.8e-10 40.5 8.2 3.7e-10 39.5 8.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 CEH12203.1 - 0.0037 17.1 0.2 0.0037 17.1 0.2 2.5 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain C1_1 PF00130.22 CEH12203.1 - 0.1 12.5 1.6 0.27 11.2 1.6 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4451 PF14616.6 CEH12203.1 - 4 7.7 6.5 2.6 8.3 0.4 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4451) SR-25 PF10500.9 CEH12204.1 - 0.00015 21.5 17.9 0.00015 21.5 17.9 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Mucin PF01456.17 CEH12204.1 - 0.0059 16.6 5.1 0.0059 16.6 5.1 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein Herpes_TAF50 PF03326.13 CEH12204.1 - 0.017 13.8 2.6 0.028 13.1 2.6 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) LMBR1 PF04791.16 CEH12204.1 - 0.1 11.5 3.5 0.14 11.0 3.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SSP160 PF06933.11 CEH12204.1 - 0.77 7.9 15.1 1.1 7.4 15.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF936 PF06075.12 CEH12204.1 - 0.93 8.3 27.8 1.2 7.9 27.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Macoilin PF09726.9 CEH12204.1 - 1.3 7.5 26.3 1.8 7.0 26.3 1.1 1 0 0 1 1 1 0 Macoilin family RNA_pol_Rpc4 PF05132.14 CEH12204.1 - 6.4 7.2 28.0 13 6.2 12.8 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Striatin PF08232.12 CEH12204.1 - 6.7 7.3 24.2 11 6.6 9.7 2.4 2 0 0 2 2 2 0 Striatin family DUF4614 PF15391.6 CEH12204.1 - 7.4 6.5 35.2 1.9 8.4 10.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) SCP2 PF02036.17 CEH12205.1 - 1.4e-23 83.3 1.1 1.9e-23 82.9 1.1 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CEH12205.1 - 4.2e-05 23.8 0.3 5.5e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Rep_fac-A_C PF08646.10 CEH12205.1 - 0.046 13.5 0.4 0.071 12.9 0.4 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain Cation_efflux PF01545.21 CEH12206.1 - 1.1e-47 162.4 19.4 1.3e-46 158.9 19.4 2.1 1 1 0 1 1 1 1 Cation efflux family MerC PF03203.14 CEH12206.1 - 5.1 7.6 7.7 2.3 8.7 0.6 2.9 2 1 1 3 3 3 0 MerC mercury resistance protein Glutaredoxin PF00462.24 CEH12207.1 - 3.4e-20 72.0 0.0 1.4e-18 66.8 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 CEH12207.1 - 1.9e-12 47.1 0.0 2.9e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEH12207.1 - 0.0056 17.1 0.0 0.47 10.9 0.0 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEH12207.1 - 0.0066 16.8 0.0 0.2 12.0 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 CEH12207.1 - 0.035 14.1 0.1 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain Phosducin PF02114.16 CEH12207.1 - 0.036 13.0 0.0 0.062 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosducin HyaE PF07449.11 CEH12207.1 - 0.055 13.4 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Period_C PF12114.8 CEH12207.1 - 0.14 11.7 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region KH_1 PF00013.29 CEH12208.1 - 2.9e-07 30.2 0.1 2.3e-06 27.4 0.2 2.1 2 0 0 2 2 2 1 KH domain Lsr2 PF11774.8 CEH12209.1 - 0.088 13.0 0.0 0.095 12.9 0.0 1.0 1 0 0 1 1 1 0 Lsr2 SNF2_N PF00176.23 CEH12210.1 - 2.4e-54 184.4 0.1 8e-27 93.9 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CEH12210.1 - 2e-12 47.4 0.1 6.5e-11 42.6 0.2 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 CEH12210.1 - 3.1e-09 37.0 5.1 9.6e-09 35.4 5.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CEH12210.1 - 4.2e-08 32.9 2.7 7.4e-08 32.1 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEH12210.1 - 4.7e-08 32.9 8.5 1e-07 31.8 8.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEH12210.1 - 1.5e-07 31.1 5.8 3e-07 30.2 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH12210.1 - 2e-07 30.9 3.7 3.8e-07 29.9 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CEH12210.1 - 2.5e-06 27.2 6.3 4.9e-06 26.3 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEH12210.1 - 0.00021 21.4 7.6 0.00041 20.5 7.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CEH12210.1 - 0.00028 21.1 1.8 0.00075 19.7 1.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CEH12210.1 - 0.00036 20.3 6.8 0.002 17.9 7.1 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CEH12210.1 - 0.00062 19.4 6.5 0.0014 18.4 6.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-Nse PF11789.8 CEH12210.1 - 0.0055 16.5 3.2 0.014 15.2 3.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 CEH12210.1 - 0.058 13.1 3.2 2.8 7.7 3.9 2.3 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_6 PF14835.6 CEH12210.1 - 0.2 11.6 1.4 0.58 10.1 1.4 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CEH12210.1 - 0.24 11.2 2.7 0.48 10.3 2.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 CEH12210.1 - 0.31 11.0 3.1 0.73 9.8 3.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) KELK PF15796.5 CEH12210.1 - 1.2 9.6 5.7 0.85 10.1 1.1 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SET PF00856.28 CEH12211.1 - 2.4e-17 63.9 0.1 5e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 CEH12211.1 - 1.9e-15 57.4 4.4 1.9e-15 57.4 4.4 2.0 2 0 0 2 2 2 1 Pre-SET motif preSET_CXC PF18264.1 CEH12211.1 - 0.0067 16.9 6.0 0.0067 16.9 6.0 2.9 3 0 0 3 3 3 1 CXC domain HAD_2 PF13419.6 CEH12212.1 - 4.7e-17 62.6 0.0 6.8e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEH12212.1 - 1.4e-08 35.3 0.0 1.3e-06 28.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEH12212.1 - 0.00033 20.7 0.0 0.00085 19.3 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CEH12212.1 - 0.023 15.1 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NPR3 PF03666.13 CEH12215.1 - 1.8e-76 257.8 1.3 6.1e-37 127.5 0.0 3.3 2 1 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 ATP-synt_8 PF00895.20 CEH12215.1 - 0.018 15.5 0.1 0.042 14.3 0.1 1.6 1 0 0 1 1 1 0 ATP synthase protein 8 ABC_trans_N PF14510.6 CEH12215.1 - 1.2 9.8 7.1 0.69 10.6 2.0 3.3 2 0 0 2 2 2 0 ABC-transporter N-terminal TetR_C_33 PF13305.6 CEH12217.1 - 0.013 16.2 2.2 0.14 12.9 0.4 3.2 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Herpes_UL17 PF04559.12 CEH12218.1 - 0.99 8.1 13.6 0.53 9.0 2.1 2.2 2 0 0 2 2 2 0 Herpesvirus UL17 protein E1-E2_ATPase PF00122.20 CEH12220.1 - 1.4e-37 129.0 13.3 1.4e-28 99.6 0.0 3.6 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEH12220.1 - 1.2e-27 96.8 2.5 1.2e-27 96.8 2.5 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CEH12220.1 - 5.4e-21 75.8 0.1 4.5e-20 72.8 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEH12220.1 - 1e-16 60.3 0.0 1e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEH12220.1 - 6.6e-15 55.0 0.0 1.6e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEH12220.1 - 1.3e-07 31.6 0.2 5.1e-05 23.1 0.4 2.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase ABC2_membrane_5 PF13346.6 CEH12220.1 - 2.4 7.7 7.7 0.47 10.0 0.5 2.9 3 0 0 3 3 3 0 ABC-2 family transporter protein DUF543 PF04418.12 CEH12221.1 - 1e-16 60.7 1.0 3.3e-15 55.8 1.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF543) DUF883 PF05957.13 CEH12221.1 - 0.006 17.2 0.6 0.14 12.7 0.5 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) GCV_T PF01571.21 CEH12222.1 - 3.5e-80 269.1 0.0 4.4e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CEH12222.1 - 5.1e-21 74.4 0.2 1.9e-20 72.5 0.2 1.9 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Cutinase PF01083.22 CEH12223.1 - 8.9e-21 74.6 0.1 1.3e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CEH12223.1 - 2.5e-06 27.2 0.1 3.7e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 CEH12223.1 - 0.00032 20.4 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 CEH12223.1 - 0.00034 20.5 0.0 0.00046 20.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF3089 PF11288.8 CEH12223.1 - 0.0019 17.8 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Peptidase_S9 PF00326.21 CEH12223.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family VirJ PF06057.11 CEH12223.1 - 0.035 14.0 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.20 CEH12223.1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.8 CEH12223.1 - 0.07 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ATP-synt_10 PF05176.14 CEH12224.1 - 3.8e-60 203.3 0.0 4.6e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Peptidase_M43 PF05572.13 CEH12225.1 - 1.1e-19 70.9 0.0 2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 CEH12225.1 - 1.3e-05 25.7 0.0 2.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CEH12225.1 - 4.7e-05 23.6 0.9 8.2e-05 22.8 0.9 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CEH12225.1 - 0.0052 16.4 1.2 0.013 15.1 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CEH12225.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M57 PF12388.8 CEH12225.1 - 0.2 11.3 7.9 0.32 10.6 1.7 2.2 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase 3-alpha PF03475.14 CEH12226.1 - 0.098 12.5 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 3-alpha domain Fas_alpha_ACP PF18325.1 CEH12227.1 - 5.4e-71 238.2 0.0 2.3e-70 236.1 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 CEH12227.1 - 1.4e-67 227.3 0.0 2.2e-67 226.6 0.0 1.3 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain adh_short PF00106.25 CEH12227.1 - 8.8e-09 35.1 0.2 3.6e-08 33.1 0.1 2.1 2 1 1 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH12227.1 - 5.6e-07 29.3 0.1 1e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acyl_transf_1 PF00698.21 CEH12227.1 - 7.1e-05 22.5 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 CEH12227.1 - 0.015 15.2 0.0 0.052 13.5 0.0 2.0 1 0 0 1 1 1 0 KR domain DUF3198 PF11433.8 CEH12227.1 - 0.062 13.2 0.2 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) Catalase-rel PF06628.12 CEH12227.1 - 0.2 11.9 0.3 1.5 9.1 0.0 2.5 2 1 0 2 2 2 0 Catalase-related immune-responsive DUF1729 PF08354.10 CEH12228.1 - 2.5e-66 224.0 0.0 4e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 CEH12228.1 - 5.6e-40 137.8 0.0 8.9e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain FAS_meander PF17951.1 CEH12228.1 - 1.4e-37 128.8 0.0 2.7e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 CEH12228.1 - 3.7e-30 104.0 0.0 7e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CEH12228.1 - 2.2e-05 24.6 0.0 8.5e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Mito_carr PF00153.27 CEH12229.1 - 4.3e-60 199.6 4.9 3.5e-24 84.6 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 CEH12229.1 - 0.0048 16.7 0.1 0.02 14.8 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CEH12229.1 - 0.014 15.9 0.1 0.19 12.2 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 CEH12229.1 - 0.045 13.3 0.1 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 EF hand PPTA PF01239.22 CEH12230.1 - 3.2e-41 137.9 7.5 3e-08 33.1 1.6 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 CEH12230.1 - 0.031 14.7 0.1 2.3 8.8 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Velvet PF11754.8 CEH12230.1 - 0.079 12.9 3.4 0.12 12.3 3.4 1.2 1 0 0 1 1 1 0 Velvet factor Thioredoxin_12 PF18400.1 CEH12230.1 - 0.19 11.5 5.1 0.22 11.4 3.5 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain Zip PF02535.22 CEH12230.1 - 0.21 10.7 5.4 0.28 10.4 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CEH12230.1 - 0.47 9.2 7.0 0.63 8.7 7.0 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CEH12230.1 - 0.68 10.0 4.7 0.96 9.5 4.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 CEH12230.1 - 2.4 6.2 4.3 3.1 5.8 4.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec62 PF03839.16 CEH12230.1 - 6.2 6.3 12.8 4.6 6.7 8.2 2.7 3 1 0 3 3 3 0 Translocation protein Sec62 ArfGap PF01412.18 CEH12232.1 - 1.2e-39 135.0 0.2 1.7e-39 134.5 0.2 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NIR_SIR PF01077.22 CEH12234.1 - 2.9e-41 140.6 0.0 5.6e-39 133.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 CEH12234.1 - 7.2e-29 99.4 0.0 2.1e-14 53.1 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 CEH12234.1 - 4.9e-26 91.7 0.0 8.7e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 CEH12234.1 - 4.6e-07 29.8 0.1 8.9e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Fungal_trans PF04082.18 CEH12237.1 - 1.2e-05 24.5 0.0 2.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDC27 PF09507.10 CEH12237.1 - 0.039 13.4 7.3 0.058 12.8 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1266 PF06889.11 CEH12237.1 - 0.095 12.7 2.8 0.46 10.5 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1266) Presenilin PF01080.17 CEH12237.1 - 3.5 6.3 5.0 5.4 5.7 5.0 1.1 1 0 0 1 1 1 0 Presenilin Aminotran_3 PF00202.21 CEH12238.1 - 2.6e-22 79.1 0.0 2.6e-14 52.7 0.0 3.0 2 1 0 2 2 2 2 Aminotransferase class-III V-ATPase_H_N PF03224.14 CEH12241.1 - 3.3e-65 220.4 0.0 3.9e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H LANC_like PF05147.13 CEH12241.1 - 0.14 10.7 0.0 0.36 9.4 0.0 1.6 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein V-ATPase_H_C PF11698.8 CEH12242.1 - 1e-23 83.7 0.0 1.1e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit H IBN_N PF03810.19 CEH12242.1 - 0.035 14.0 0.1 0.32 10.9 0.1 2.1 2 0 0 2 2 2 0 Importin-beta N-terminal domain Peptidase_M9_N PF08453.10 CEH12242.1 - 0.044 13.5 0.0 0.06 13.1 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M9 N-terminal HEAT PF02985.22 CEH12242.1 - 0.057 13.7 0.5 0.24 11.7 0.1 2.2 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 CEH12242.1 - 0.074 13.4 0.1 0.35 11.3 0.1 1.9 1 1 1 2 2 2 0 HEAT repeats NOG1_N PF17835.1 CEH12242.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NOG1 N-terminal helical domain ACOX PF01756.19 CEH12244.1 - 2.4e-43 147.8 0.0 5.4e-43 146.6 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CEH12244.1 - 2.9e-20 72.3 0.1 7.1e-20 71.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 CEH12244.1 - 1.1e-10 42.1 0.1 9.5e-10 39.1 0.0 2.4 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 CEH12244.1 - 5e-05 23.6 2.1 0.00025 21.3 2.1 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain APT PF03440.14 CEH12244.1 - 0.032 14.2 0.0 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 Aerolysin/Pertussis toxin (APT) domain Abhydrolase_2 PF02230.16 CEH12245.1 - 2.2e-15 57.1 0.0 2.8e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase TPR_7 PF13176.6 CEH12246.1 - 0.28 11.3 1.8 0.85 9.8 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PINIT PF14324.6 CEH12247.1 - 3.1e-17 63.3 0.0 4.6e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 CEH12247.1 - 1.5e-16 59.9 0.5 2.3e-16 59.2 0.5 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CEH12247.1 - 3.2e-08 33.3 0.1 6.1e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 CEH12247.1 - 1.2e-06 28.1 0.0 3.3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 SAP domain UBA2_C PF16195.5 CEH12247.1 - 0.018 15.8 1.8 0.018 15.8 1.8 3.3 3 0 0 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus Methyltransf_2 PF00891.18 CEH12248.1 - 2.2e-21 76.1 0.0 3.1e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain TFIIF_alpha PF05793.12 CEH12249.1 - 0.5 8.9 4.9 0.65 8.5 4.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_M28 PF04389.17 CEH12251.1 - 8e-18 64.8 0.0 1.5e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CEH12251.1 - 3.2e-09 36.7 0.3 3.4e-08 33.4 0.1 2.4 2 0 0 2 2 2 1 PA domain Dynamin_M PF01031.20 CEH12252.1 - 1.3e-103 346.2 0.0 2.5e-103 345.2 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CEH12252.1 - 2.3e-54 183.9 0.0 4.8e-54 182.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CEH12252.1 - 3.1e-29 101.0 9.8 4.9e-29 100.3 6.3 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CEH12252.1 - 0.00043 20.4 0.1 0.0045 17.0 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 CEH12252.1 - 0.032 14.0 0.5 2.6 7.7 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 CEH12252.1 - 0.081 13.3 0.1 0.53 10.6 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain FSH1 PF03959.13 CEH12253.1 - 3.4e-47 160.8 0.0 5.3e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) CDC45 PF02724.14 CEH12253.1 - 0.0038 15.6 0.1 0.0049 15.2 0.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Abhydrolase_1 PF00561.20 CEH12253.1 - 0.047 13.3 0.0 6.1 6.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.11 CEH12253.1 - 0.079 12.9 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3180 PF11377.8 CEH12254.1 - 0.039 14.1 2.6 0.073 13.2 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) Gpi16 PF04113.14 CEH12255.1 - 7e-59 199.7 0.4 1.8e-21 76.2 0.1 3.0 2 1 1 3 3 3 3 Gpi16 subunit, GPI transamidase component ACP_syn_III_C PF08541.10 CEH12256.1 - 0.0022 18.1 0.0 0.0038 17.4 0.0 1.3 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Nmad5 PF18757.1 CEH12256.1 - 0.089 13.0 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 ATPase_2 PF01637.18 CEH12256.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea MFS_1 PF07690.16 CEH12259.1 - 3.1e-24 85.5 18.3 4.1e-24 85.2 18.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FixP_N PF14715.6 CEH12259.1 - 0.13 12.1 1.4 3.1 7.6 0.1 2.8 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Peptidase_C97 PF05903.14 CEH12260.1 - 7.5e-33 113.5 0.0 1.2e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 CEH12260.1 - 2.8e-17 62.9 5.9 6.7e-17 61.6 5.9 1.5 1 1 0 1 1 1 1 PUL domain Thioredoxin_2 PF13098.6 CEH12260.1 - 0.12 12.9 0.0 0.3 11.5 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 CEH12260.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Exo_endo_phos PF03372.23 CEH12261.1 - 2.2e-06 27.4 0.0 6.3e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1640 PF07798.11 CEH12262.1 - 4.7e-49 166.8 1.4 8e-49 166.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4407 PF14362.6 CEH12262.1 - 0.46 9.8 6.3 0.32 10.3 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Lipoprotein_15 PF03640.15 CEH12263.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Secreted repeat of unknown function MTHFR PF02219.17 CEH12264.1 - 3.6e-84 282.5 0.0 1.4e-61 208.4 0.0 4.0 2 1 1 3 3 3 3 Methylenetetrahydrofolate reductase SUZ PF12752.7 CEH12264.1 - 1.7 9.4 4.8 10 7.0 0.3 2.6 2 0 0 2 2 2 0 SUZ domain TFCD_C PF12612.8 CEH12267.1 - 4.5e-31 108.2 0.2 8.6e-30 104.0 0.0 3.2 2 1 0 3 3 3 1 Tubulin folding cofactor D C terminal RTP1_C1 PF10363.9 CEH12267.1 - 0.0052 17.0 0.0 4.4 7.5 0.0 3.5 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 CEH12267.1 - 0.0066 17.0 0.0 0.32 11.6 0.0 3.2 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CEH12267.1 - 0.0097 16.1 0.0 0.0097 16.1 0.0 8.8 10 0 0 10 10 10 1 HEAT repeat Cnd1 PF12717.7 CEH12267.1 - 0.01 15.9 0.0 3 7.9 0.0 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CEH12267.1 - 0.047 14.2 9.5 15 6.2 0.0 6.6 5 1 1 6 6 6 0 HEAT-like repeat HEAT_2 PF13646.6 CEH12267.1 - 0.2 12.1 11.1 0.95 9.9 0.0 5.6 6 0 0 6 6 6 0 HEAT repeats Arm PF00514.23 CEH12267.1 - 0.78 9.9 3.2 21 5.3 0.1 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 CEH12267.1 - 2 9.3 0.0 2 9.3 0.0 5.0 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Sugar_tr PF00083.24 CEH12268.1 - 8e-28 97.5 22.0 1.3e-18 67.2 10.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEH12268.1 - 2.3e-23 82.7 31.6 1.3e-16 60.5 17.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily VKG_Carbox PF05090.14 CEH12268.1 - 0.018 13.9 0.4 0.031 13.1 0.3 1.4 1 1 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase INCENP_ARK-bind PF03941.15 CEH12269.1 - 0.0066 16.4 0.2 0.0066 16.4 0.2 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Myb_DNA-bind_6 PF13921.6 CEH12270.1 - 4e-12 46.2 11.2 2.8e-06 27.5 0.1 5.4 4 1 2 6 6 6 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CEH12270.1 - 2.2e-11 43.8 16.8 0.0039 17.4 0.7 6.4 6 0 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CEH12270.1 - 0.00094 19.5 15.5 0.24 11.8 0.2 5.7 7 0 0 7 7 7 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 CEH12270.1 - 3.1 8.2 9.8 27 5.2 0.1 4.7 5 0 0 5 5 5 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PhoD PF09423.10 CEH12271.1 - 5.1e-100 334.9 4.0 6.3e-100 334.6 4.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 CEH12271.1 - 5.4e-22 78.1 0.1 1.6e-21 76.7 0.1 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 CEH12271.1 - 2.4e-05 24.8 0.0 9.5e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain NMT PF01233.19 CEH12273.1 - 1.6e-75 252.3 0.0 2.9e-75 251.5 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 CEH12273.1 - 8.6e-72 241.0 0.0 2e-71 239.8 0.0 1.6 1 1 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 CEH12273.1 - 0.00074 19.6 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEH12273.1 - 0.0015 18.8 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Abhydrolase_3 PF07859.13 CEH12276.1 - 2.2e-17 63.7 0.3 1.1e-15 58.1 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEH12276.1 - 1.3e-09 37.4 0.0 7.3e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CEH12276.1 - 0.029 13.9 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family tRNA-synt_2 PF00152.20 CEH12277.1 - 1.7e-45 155.5 0.1 5.9e-45 153.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 CEH12277.1 - 2.2e-05 23.7 0.1 3.6e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 CEH12277.1 - 3.5e-05 23.7 0.1 9e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ebp2 PF05890.12 CEH12277.1 - 0.35 10.4 6.3 0.67 9.5 6.3 1.3 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 Metallothio_5 PF02067.15 CEH12278.1 - 0.028 14.5 7.0 0.056 13.6 7.0 1.4 1 0 0 1 1 1 0 Metallothionein family 5 FDC-SP PF15215.6 CEH12278.1 - 0.11 13.1 0.1 0.18 12.4 0.1 1.3 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide TPP_enzyme_N PF02776.18 CEH12280.1 - 6.8e-21 74.6 0.2 2.8e-11 43.3 0.0 2.8 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CEH12280.1 - 9e-20 70.8 0.0 1.6e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CEH12280.1 - 1.2e-11 44.6 0.0 3.2e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Aldo_ket_red PF00248.21 CEH12281.1 - 1.5e-46 159.0 0.0 1.1e-45 156.1 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family ADC PF06314.11 CEH12282.1 - 0.0026 17.4 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Presenilin PF01080.17 CEH12282.1 - 0.049 12.4 3.4 0.095 11.5 3.4 1.5 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 CEH12282.1 - 0.23 10.4 1.9 0.33 9.9 1.9 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Spt20 PF12090.8 CEH12282.1 - 9.4 5.8 9.4 12 5.4 8.5 1.6 2 0 0 2 2 2 0 Spt20 family Xan_ur_permease PF00860.20 CEH12283.1 - 7.8e-15 54.5 21.5 2.5e-14 52.8 16.7 3.2 1 1 1 2 2 2 1 Permease family MFS_MOT1 PF16983.5 CEH12283.1 - 0.018 15.5 6.9 0.018 15.5 6.9 2.2 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily FUSC-like PF12805.7 CEH12283.1 - 1.9 7.5 6.5 1.2 8.2 4.4 1.7 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Rav1p_C PF12234.8 CEH12285.1 - 5.2e-145 484.4 0.0 6.6e-145 484.0 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal GFA PF04828.14 CEH12286.1 - 1.9e-22 79.4 0.7 3.4e-22 78.6 0.7 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 CEH12286.1 - 0.042 14.0 3.5 0.92 9.7 0.1 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Rpr2 PF04032.16 CEH12286.1 - 0.18 12.1 2.1 0.45 10.8 0.0 2.2 1 1 2 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Kinesin PF00225.23 CEH12287.1 - 8.1e-61 205.8 0.0 1e-60 205.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEH12287.1 - 2.2e-12 47.1 0.0 3.5e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Big_1 PF02369.16 CEH12288.1 - 0.057 13.4 2.5 3.2 7.8 0.1 2.4 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 1) ZirS_C PF16583.5 CEH12288.1 - 0.073 12.6 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain NEL PF14496.6 CEH12291.1 - 2.7e-31 108.7 3.6 3.1e-31 108.5 3.6 1.0 1 0 0 1 1 1 1 C-terminal novel E3 ligase, LRR-interacting HTH_Tnp_Tc3_1 PF11427.8 CEH12291.1 - 0.11 12.3 0.2 0.5 10.2 0.1 2.0 2 0 0 2 2 2 0 Tc3 transposase CN_hydrolase PF00795.22 CEH12294.1 - 3e-40 138.2 0.0 3.6e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Chromate_transp PF02417.15 CEH12295.1 - 1.5e-59 200.6 30.9 2e-33 115.8 12.3 2.2 2 0 0 2 2 2 2 Chromate transporter SUIM_assoc PF16619.5 CEH12295.1 - 2.4 8.3 9.4 6.6 6.9 9.4 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Zip PF02535.22 CEH12296.1 - 0.077 12.2 0.1 0.077 12.2 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4171 PF13775.6 CEH12296.1 - 0.29 11.6 5.4 0.38 11.2 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) SelP_N PF04592.14 CEH12296.1 - 1.3 8.3 12.4 1.5 8.2 12.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region F_actin_cap_B PF01115.17 CEH12301.1 - 2.3e-75 253.3 0.0 3e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit RhoGEF PF00621.20 CEH12302.1 - 1.3e-34 120.1 0.0 2.4e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF2093 PF09866.9 CEH12302.1 - 0.019 14.4 0.0 0.019 14.4 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2093) Syntaxin-6_N PF09177.11 CEH12302.1 - 0.49 11.0 5.5 1.2 9.7 0.2 3.8 3 1 1 4 4 4 0 Syntaxin 6, N-terminal zf-C4H2 PF10146.9 CEH12302.1 - 3 8.1 6.9 8.2 6.7 5.0 2.6 2 0 0 2 2 2 0 Zinc finger-containing protein WD40 PF00400.32 CEH12303.1 - 3e-18 65.8 5.3 1.4e-06 28.9 0.1 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase PF00069.25 CEH12303.1 - 6.1e-14 52.0 0.0 4.7e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain HEAT PF02985.22 CEH12303.1 - 1.9e-08 33.8 7.7 0.015 15.5 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 CEH12303.1 - 3.2e-06 27.5 3.4 0.13 12.7 0.0 4.4 4 1 1 5 5 5 2 HEAT repeats Pkinase_Tyr PF07714.17 CEH12303.1 - 3.3e-06 26.6 0.0 0.011 15.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Cnd1 PF12717.7 CEH12303.1 - 0.00039 20.5 0.2 0.039 14.0 0.1 2.8 2 2 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 CEH12303.1 - 0.0026 17.1 0.0 0.0086 15.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like HEAT_EZ PF13513.6 CEH12303.1 - 0.033 14.7 0.8 41 4.8 0.2 4.0 3 0 0 3 3 3 0 HEAT-like repeat Pox_TAP PF03355.14 CEH12303.1 - 0.26 10.8 0.0 0.47 10.0 0.0 1.3 1 0 0 1 1 1 0 Viral Trans-Activator Protein Ribosomal_S2 PF00318.20 CEH12304.1 - 8.1e-29 100.4 0.1 6.2e-16 58.3 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CEH12304.1 - 3.9e-09 37.7 3.2 6.2e-09 37.1 3.2 1.3 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus RRM_1 PF00076.22 CEH12305.1 - 7.6e-17 60.9 0.0 1.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GNAT_like PF18407.1 CEH12305.1 - 0.12 12.7 0.5 0.25 11.7 0.5 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyltransferase like domain DUF4490 PF14892.6 CEH12306.1 - 0.15 12.2 0.1 0.21 11.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4490) MBOAT PF03062.19 CEH12308.1 - 3.6e-50 171.3 19.9 6.2e-50 170.5 19.9 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family GHMP_kinases_N PF00288.26 CEH12309.1 - 2.1e-10 40.7 0.2 2.1e-10 40.7 0.2 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CEH12309.1 - 0.00045 20.5 0.3 0.003 17.9 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal Atg14 PF10186.9 CEH12310.1 - 7.9e-14 51.5 2.5 1.5e-13 50.6 2.5 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 SKA2 PF16740.5 CEH12310.1 - 0.36 10.6 3.6 10 5.9 0.1 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 FA_desaturase PF00487.24 CEH12310.1 - 1.3 8.8 4.4 2.8 7.7 4.4 1.5 1 0 0 1 1 1 0 Fatty acid desaturase RPA43_OB PF17875.1 CEH12311.1 - 1.2e-20 74.4 0.4 1.2e-20 74.4 0.4 4.3 3 2 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 CEH12311.1 - 2.1e-05 24.8 0.0 3.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SDP_N PF12278.8 CEH12312.1 - 7.7 6.7 19.5 0.61 10.2 8.1 2.8 2 0 0 2 2 2 0 Sex determination protein N terminal Vac14_Fig4_bd PF11916.8 CEH12313.1 - 2.1e-79 265.3 6.9 2.1e-79 265.3 6.9 2.5 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CEH12313.1 - 1.5e-45 153.7 0.0 8.3e-41 138.5 0.0 4.7 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CEH12313.1 - 7.7e-12 44.4 5.0 0.00035 20.6 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 CEH12313.1 - 3.6e-07 30.5 1.1 0.086 13.4 0.0 6.5 6 0 0 6 6 6 1 HEAT-like repeat Cnd1 PF12717.7 CEH12313.1 - 8.8e-07 29.1 0.4 0.058 13.4 0.4 3.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CEH12313.1 - 1.6e-05 24.6 0.2 1.9 8.0 0.0 4.3 3 1 1 4 4 4 2 CLASP N terminal HEAT_2 PF13646.6 CEH12313.1 - 0.00052 20.3 11.4 6.3 7.3 0.1 6.8 7 1 0 7 7 7 2 HEAT repeats MMS19_C PF12460.8 CEH12313.1 - 0.00078 18.7 4.5 1.1 8.3 0.0 4.2 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 CEH12313.1 - 0.0035 17.3 0.0 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Arm PF00514.23 CEH12313.1 - 0.0074 16.3 0.1 32 4.8 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat ParcG PF10274.9 CEH12313.1 - 0.0094 16.1 0.5 3.7 7.6 0.0 3.6 4 0 0 4 4 4 1 Parkin co-regulated protein Tti2 PF10521.9 CEH12313.1 - 0.017 14.6 2.4 3 7.3 0.0 3.8 5 1 1 6 6 6 0 Tti2 family MIP PF00230.20 CEH12314.1 - 8.4e-07 28.9 8.8 1.4e-06 28.2 8.8 1.3 1 0 0 1 1 1 1 Major intrinsic protein Dor1 PF04124.12 CEH12314.1 - 0.27 9.9 0.7 0.42 9.3 0.7 1.1 1 0 0 1 1 1 0 Dor1-like family AAA PF00004.29 CEH12317.1 - 3.9e-14 53.2 0.0 8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEH12317.1 - 9.1e-11 42.4 0.0 1.7e-09 38.3 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 CEH12317.1 - 6.1e-10 39.1 0.0 1.4e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 CEH12317.1 - 2.8e-07 30.9 0.0 6.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH12317.1 - 0.00077 19.8 0.1 0.003 17.9 0.1 2.0 2 0 0 2 2 1 1 AAA domain Spt5_N PF11942.8 CEH12317.1 - 0.012 16.6 1.9 0.012 16.6 1.9 2.0 2 0 0 2 2 1 0 Spt5 transcription elongation factor, acidic N-terminal TFIIA PF03153.13 CEH12317.1 - 0.026 14.5 3.1 0.042 13.8 3.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_30 PF13604.6 CEH12317.1 - 0.086 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 CEH12317.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.6 CEH12317.1 - 0.14 12.7 0.1 0.51 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CEH12317.1 - 0.14 12.0 0.0 0.57 10.1 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 CEH12317.1 - 0.24 11.1 0.9 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CEH12317.1 - 0.24 11.3 0.0 3 7.7 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Cwf_Cwc_15 PF04889.12 CEH12317.1 - 3.2 7.4 12.0 5.2 6.7 12.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 CEH12317.1 - 4.6 6.5 7.3 7.1 5.9 7.3 1.2 1 0 0 1 1 1 0 NOA36 protein ORMDL PF04061.14 CEH12318.1 - 3.7e-55 185.5 2.2 4.6e-55 185.1 2.2 1.1 1 0 0 1 1 1 1 ORMDL family GTP_EFTU PF00009.27 CEH12320.1 - 3.6e-53 180.0 0.0 5.8e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CEH12320.1 - 6.3e-10 39.0 0.0 1.6e-07 31.3 0.0 2.5 1 1 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.6 CEH12320.1 - 5.4e-08 32.8 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CEH12320.1 - 2e-06 28.1 0.0 4.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEH12320.1 - 0.004 17.2 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FATC PF02260.20 CEH12321.1 - 0.46 10.4 3.5 0.98 9.3 3.5 1.5 1 0 0 1 1 1 0 FATC domain PRIMA1 PF16101.5 CEH12321.1 - 0.78 9.8 5.9 5.3 7.1 2.3 3.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Peptidase_C14 PF00656.22 CEH12322.1 - 3.9e-58 197.3 0.0 4.8e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain ThiC-associated PF13667.6 CEH12322.1 - 0.17 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain DHFR_1 PF00186.19 CEH12323.1 - 2.5e-22 79.3 0.0 5.6e-11 42.4 0.0 3.5 2 1 0 2 2 2 2 Dihydrofolate reductase DEAD_2 PF06733.15 CEH12324.1 - 1.1e-48 165.2 0.0 8e-48 162.4 0.0 2.1 1 1 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CEH12324.1 - 1.1e-45 155.9 0.1 3.3e-45 154.3 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 CEH12324.1 - 1e-40 139.5 2.2 1.1e-36 126.3 0.4 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 CEH12324.1 - 0.00013 22.0 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CEH12324.1 - 0.22 10.2 0.1 1.8 7.2 0.1 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain PhnJ PF06007.11 CEH12326.1 - 0.099 11.6 0.2 0.17 10.9 0.2 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ IMS PF00817.20 CEH12327.1 - 2.1e-28 99.2 0.0 3.8e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CEH12327.1 - 2.3e-06 28.3 0.0 8.2e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 CEH12327.1 - 0.00027 20.3 4.7 0.00069 19.0 1.3 2.7 2 0 0 2 2 2 1 Ubiquitin binding region 14-3-3 PF00244.20 CEH12328.1 - 2.9e-107 357.2 4.5 4.2e-107 356.7 4.5 1.2 1 0 0 1 1 1 1 14-3-3 protein WD40 PF00400.32 CEH12328.1 - 6.1e-07 30.1 9.4 0.075 13.9 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH12328.1 - 7.6e-05 22.9 0.0 0.036 14.3 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain FlaF PF07309.11 CEH12328.1 - 0.047 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF Coatomer_E PF04733.14 CEH12329.1 - 7.7e-42 143.7 0.0 9.2e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_11 PF13414.6 CEH12329.1 - 0.099 12.3 0.6 0.75 9.5 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 CEH12329.1 - 1 9.7 6.7 1.9 8.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEH12329.1 - 3.9 8.5 14.5 6.2 7.9 0.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat Clathrin_lg_ch PF01086.17 CEH12330.1 - 2.3e-49 168.5 3.3 3.4e-49 168.0 3.3 1.2 1 0 0 1 1 1 1 Clathrin light chain IATP PF04568.12 CEH12330.1 - 0.052 14.0 0.4 0.052 14.0 0.4 2.1 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Erythro_esteras PF05139.14 CEH12330.1 - 0.32 10.8 4.6 0.47 10.2 4.6 1.2 1 0 0 1 1 1 0 Erythromycin esterase DUF3128 PF11326.8 CEH12332.1 - 9.4e-20 70.8 2.2 1.7e-19 69.9 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Ndufs5 PF10200.9 CEH12332.1 - 0.064 13.5 0.2 0.11 12.8 0.2 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa M-factor PF03855.13 CEH12332.1 - 2 8.6 4.6 4.2 7.6 4.6 1.5 1 0 0 1 1 1 0 M-factor Methyltransf_16 PF10294.9 CEH12333.1 - 2.4e-14 53.4 0.0 1e-13 51.4 0.0 1.9 2 1 0 2 2 2 1 Lysine methyltransferase Methyltransf_25 PF13649.6 CEH12333.1 - 0.0062 17.2 0.0 0.019 15.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH12333.1 - 0.13 13.0 0.0 0.42 11.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CEH12333.1 - 0.17 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TOM13 PF08219.11 CEH12334.1 - 2e-08 34.1 0.3 4.4e-08 33.0 0.3 1.5 1 0 0 1 1 1 1 Outer membrane protein TOM13 ThrE_2 PF12821.7 CEH12334.1 - 0.18 12.0 0.4 0.26 11.5 0.4 1.2 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE RRM_1 PF00076.22 CEH12336.1 - 6.5e-15 54.7 0.0 8.9e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEH12336.1 - 0.0084 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) He_PIG PF05345.12 CEH12340.1 - 5.2e-07 29.7 13.2 0.019 15.1 0.4 5.5 5 1 1 6 6 6 3 Putative Ig domain BACON PF13004.7 CEH12340.1 - 0.11 12.5 0.6 0.91 9.6 0.0 2.8 3 0 0 3 3 3 0 Putative binding domain, N-terminal CMAS PF02353.20 CEH12341.1 - 2.6e-29 102.3 0.7 3.8e-29 101.8 0.7 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CEH12341.1 - 4.6e-13 49.7 0.0 1.9e-12 47.7 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH12341.1 - 3.4e-12 46.9 0.0 1.1e-11 45.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH12341.1 - 9.5e-11 41.7 0.0 2.6e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CEH12341.1 - 1.1e-08 34.8 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CEH12341.1 - 1e-07 32.6 0.0 2.9e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH12341.1 - 3.8e-06 26.8 0.0 8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEH12341.1 - 0.00027 20.4 0.0 0.00054 19.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.14 CEH12341.1 - 0.0003 20.3 0.0 0.00066 19.1 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 CEH12341.1 - 0.0019 17.8 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 CEH12341.1 - 0.0061 16.3 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 CEH12341.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltr_RsmB-F PF01189.17 CEH12341.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 CEH12341.1 - 0.039 13.3 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 CEH12341.1 - 0.048 13.8 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase TRM13 PF05206.14 CEH12341.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 DOT1 PF08123.13 CEH12341.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF938 PF06080.12 CEH12341.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Adap_comp_sub PF00928.21 CEH12342.1 - 6.1e-93 311.0 0.1 1.3e-92 310.0 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CEH12342.1 - 1.7e-06 28.0 0.2 3.1e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CEH12342.1 - 0.033 13.6 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Iso_dh PF00180.20 CEH12343.1 - 1.3e-116 389.6 0.0 1.5e-116 389.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase 4HBT_3 PF13622.6 CEH12345.1 - 4.5e-11 43.5 0.2 6.3e-11 43.0 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily PP2C PF00481.21 CEH12346.1 - 2.2e-27 96.3 0.0 9e-27 94.3 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C Cyt-b5 PF00173.28 CEH12346.1 - 3.1e-21 75.3 0.0 6.6e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SNF2_N PF00176.23 CEH12347.1 - 5.1e-58 196.5 0.0 7.7e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEH12347.1 - 2.8e-17 63.0 0.0 8.1e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain cwf18 PF08315.12 CEH12348.1 - 7.2e-31 107.6 11.4 1e-30 107.2 11.4 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Sigma70_r2 PF04542.14 CEH12348.1 - 0.0087 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Zn_clus PF00172.18 CEH12349.1 - 1.2e-06 28.5 8.1 2.1e-06 27.8 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3782 PF12644.7 CEH12349.1 - 0.0044 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3782) TetR_C_9 PF14514.6 CEH12349.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Cauli_VI PF01693.16 CEH12350.1 - 1.5e-09 38.0 0.1 3.3e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin COX14 PF14880.6 CEH12351.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c assembly PH PF00169.29 CEH12352.1 - 5.3e-13 49.4 0.0 9.6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 CEH12352.1 - 6.4e-13 48.4 0.1 1.3e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEH12352.1 - 9.8e-13 47.5 0.3 2.1e-12 46.4 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEH12352.1 - 8.7e-09 34.9 0.0 2.1e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 CEH12352.1 - 6.1e-07 29.5 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEH12352.1 - 1.5e-05 25.3 0.1 3.1e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 CEH12352.1 - 0.07 13.4 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Ssu72 PF04722.13 CEH12353.1 - 1.1e-85 286.1 0.0 1.2e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Nucleoporin_FG PF13634.6 CEH12354.1 - 2.2e-05 25.2 81.0 0.012 16.4 39.5 3.2 1 1 2 3 3 3 3 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 CEH12354.1 - 0.00048 18.8 0.1 0.00048 18.8 0.1 3.7 1 1 1 3 3 3 1 Nucleoporin FG repeated region Spc7 PF08317.11 CEH12354.1 - 0.091 11.6 0.5 0.15 10.9 0.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Tup_N PF08581.10 CEH12355.1 - 0.021 15.1 0.1 0.021 15.1 0.1 2.1 2 0 0 2 2 2 0 Tup N-terminal DUF3450 PF11932.8 CEH12355.1 - 8 5.7 9.4 0.27 10.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Snf7 PF03357.21 CEH12357.1 - 7.8e-15 54.9 11.1 9.6e-15 54.6 11.1 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 CEH12357.1 - 0.0012 18.8 3.1 0.0018 18.2 3.1 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 CEH12357.1 - 0.0084 15.8 0.2 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase SidC_N PF18219.1 CEH12357.1 - 0.057 12.4 1.6 0.075 12.0 1.6 1.2 1 0 0 1 1 1 0 SidC N-terminal domain FKBP_C PF00254.28 CEH12357.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3591 PF12157.8 CEH12358.1 - 1.2e-176 587.7 2.4 1.9e-176 587.1 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 CEH12358.1 - 7.3e-06 25.7 1.2 1.7e-05 24.5 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Ribosomal_L44 PF00935.19 CEH12358.1 - 0.25 11.9 1.6 1.1 9.7 1.6 2.1 1 0 0 1 1 1 0 Ribosomal protein L44 zf-CCHC PF00098.23 CEH12358.1 - 0.3 11.2 1.2 0.55 10.4 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle UAA PF08449.11 CEH12359.1 - 5e-41 140.9 5.3 8.6e-41 140.1 5.3 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 CEH12359.1 - 2.6e-07 30.9 18.6 3.6e-06 27.2 4.9 4.2 4 1 0 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CEH12359.1 - 0.0019 17.4 0.5 0.57 9.3 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 CEH12359.1 - 0.0061 15.9 6.7 0.066 12.6 6.7 2.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF5463 PF17551.2 CEH12359.1 - 0.39 10.7 1.4 1.7 8.6 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5463) Vps5 PF09325.10 CEH12360.1 - 9.9e-06 25.3 5.7 1.6e-05 24.6 5.7 1.2 1 0 0 1 1 1 1 Vps5 C terminal like BAR_3 PF16746.5 CEH12360.1 - 0.013 15.2 1.5 0.024 14.3 0.1 1.9 2 0 0 2 2 2 0 BAR domain of APPL family HBS1_N PF08938.10 CEH12360.1 - 0.12 12.7 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 HBS1 N-terminus Dynactin_p62 PF05502.13 CEH12361.1 - 4.2e-54 184.1 12.1 1.1e-50 172.8 13.0 3.0 2 1 0 2 2 2 2 Dynactin p62 family zf-piccolo PF05715.13 CEH12361.1 - 0.12 12.5 4.5 0.78 9.9 0.1 2.9 2 0 0 2 2 2 0 Piccolo Zn-finger CTNNBL PF08216.11 CEH12362.1 - 3.3e-29 101.1 0.1 7.3e-29 100.0 0.1 1.6 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DUF4704 PF15787.5 CEH12362.1 - 0.0075 15.5 0.0 0.028 13.7 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4704) RasGAP PF00616.19 CEH12363.1 - 4.1e-22 78.9 0.0 1.6e-15 57.4 0.0 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 CEH12363.1 - 2.8e-11 43.7 0.0 1.2e-10 41.6 0.0 2.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CEH12363.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 CRAL/TRIO domain TAFH PF07531.14 CEH12363.1 - 0.12 12.5 0.0 0.76 9.9 0.0 2.5 1 0 0 1 1 1 0 NHR1 homology to TAF Beta-lactamase PF00144.24 CEH12364.1 - 9.5e-28 97.4 0.2 2.1e-27 96.2 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase RF-1 PF00472.20 CEH12368.1 - 1.1e-21 77.0 0.5 1.6e-21 76.4 0.5 1.2 1 0 0 1 1 1 1 RF-1 domain HAP1_N PF04849.13 CEH12369.1 - 0.013 14.7 17.7 0.82 8.8 9.1 3.2 2 1 1 3 3 3 0 HAP1 N-terminal conserved region DUF155 PF02582.14 CEH12369.1 - 0.11 12.5 0.6 3.9 7.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 NYD-SP28_assoc PF14775.6 CEH12369.1 - 0.16 12.1 0.1 0.61 10.2 0.1 2.0 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF3138 PF11336.8 CEH12369.1 - 1.7 7.1 3.6 5.2 5.6 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Fungal_TACC PF12709.7 CEH12369.1 - 2.5 8.6 8.3 12 6.4 0.3 3.6 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4686 PF15742.5 CEH12369.1 - 3.2 6.8 14.9 1.8 7.6 10.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) TPR_MLP1_2 PF07926.12 CEH12369.1 - 7 6.7 26.5 12 6.0 3.3 3.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Coatomer_WDAD PF04053.14 CEH12370.1 - 1.7e-150 502.0 0.0 1.5e-148 495.6 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.32 CEH12370.1 - 2.9e-37 126.0 9.4 7.4e-08 32.9 0.0 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH12370.1 - 3.6e-09 36.8 0.0 0.15 12.4 0.0 6.2 6 2 2 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEH12370.1 - 0.013 14.2 0.5 0.14 10.8 0.0 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 CEH12370.1 - 0.068 12.5 0.4 0.74 9.1 0.0 2.4 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Methyltransf_25 PF13649.6 CEH12372.1 - 6.1e-13 49.3 0.0 1.5e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH12372.1 - 4.6e-11 42.8 0.0 9.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH12372.1 - 3e-10 40.6 0.0 7.1e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH12372.1 - 2.8e-05 24.8 0.0 6.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH12372.1 - 0.00059 19.7 0.0 0.0019 18.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEH12372.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CEH12372.1 - 0.0051 16.4 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain OGG_N PF07934.12 CEH12373.1 - 1e-23 83.7 0.1 3.4e-20 72.3 0.1 2.3 2 0 0 2 2 2 2 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CEH12373.1 - 3.4e-07 30.7 0.0 6.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CEH12373.1 - 0.044 13.7 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif ABC_tran PF00005.27 CEH12375.1 - 7.4e-47 159.3 0.0 1.9e-22 80.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CEH12375.1 - 7.3e-22 77.2 0.8 7.3e-22 77.2 0.8 2.8 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 CEH12375.1 - 6.4e-15 55.8 7.2 0.008 16.0 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CEH12375.1 - 7.3e-11 43.0 5.4 7.8e-05 23.3 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.6 CEH12375.1 - 3e-09 37.1 0.0 0.0082 15.9 0.1 3.9 3 1 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 CEH12375.1 - 8.7e-09 35.1 1.2 0.54 9.6 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEH12375.1 - 1.8e-08 34.0 0.3 0.0022 17.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CEH12375.1 - 8.8e-07 29.5 0.0 0.016 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CEH12375.1 - 1.4e-06 28.3 0.7 0.003 17.5 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 CEH12375.1 - 1.8e-06 28.0 0.4 0.0033 17.5 0.1 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CEH12375.1 - 7.6e-06 26.1 3.2 0.27 11.3 0.1 4.0 2 1 1 3 3 3 2 Dynamin family AAA_24 PF13479.6 CEH12375.1 - 1.1e-05 25.3 0.1 0.22 11.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 CEH12375.1 - 1.4e-05 25.1 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 CEH12375.1 - 5.8e-05 23.4 0.8 0.53 10.6 0.2 3.0 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CEH12375.1 - 6.4e-05 23.3 0.0 0.54 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CEH12375.1 - 0.00016 22.1 0.2 1.9 8.9 0.2 3.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEH12375.1 - 0.00037 21.0 0.1 1.1 9.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 CEH12375.1 - 0.001 19.1 0.6 0.47 10.4 0.1 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CEH12375.1 - 0.0014 18.9 1.6 0.71 10.3 0.0 3.2 3 0 0 3 3 3 1 RNA helicase Roc PF08477.13 CEH12375.1 - 0.0018 18.5 0.1 3.2 8.0 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 CEH12375.1 - 0.0025 17.6 4.6 0.092 12.5 0.1 3.4 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CEH12375.1 - 0.0025 18.0 0.4 1.2 9.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain FeoB_N PF02421.18 CEH12375.1 - 0.0032 17.0 0.2 0.15 11.6 0.1 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.18 CEH12375.1 - 0.0062 15.8 0.0 2.1 7.6 0.0 2.5 2 0 0 2 2 2 1 Septin FtsK_SpoIIIE PF01580.18 CEH12375.1 - 0.0077 15.6 0.2 1.4 8.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.14 CEH12375.1 - 0.0087 16.0 0.1 5.8 6.8 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 CEH12375.1 - 0.0088 15.3 0.1 1.9 7.6 0.0 2.6 3 0 0 3 3 2 1 NB-ARC domain cobW PF02492.19 CEH12375.1 - 0.0093 15.6 0.4 4.1 7.0 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 CEH12375.1 - 0.016 15.2 0.0 17 5.5 0.0 4.1 5 0 0 5 5 4 0 AAA domain DUF87 PF01935.17 CEH12375.1 - 0.02 15.0 5.6 3.5 7.7 0.0 4.2 4 1 1 5 5 4 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 CEH12375.1 - 0.022 14.4 0.0 8 6.1 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 CEH12375.1 - 0.035 13.6 0.4 2 7.9 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_25 PF13481.6 CEH12375.1 - 0.041 13.5 0.1 8.5 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CEH12375.1 - 0.043 13.1 0.0 1.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 CEH12375.1 - 0.053 13.5 0.1 5.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_27 PF13514.6 CEH12375.1 - 0.055 13.1 0.1 5.6 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.9 CEH12375.1 - 0.072 12.3 1.3 4.2 6.4 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.9 CEH12375.1 - 0.077 12.7 1.3 13 5.5 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 CEH12375.1 - 0.081 11.9 0.0 14 4.5 0.0 2.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 CEH12375.1 - 0.089 12.7 6.1 1.9 8.3 0.1 4.0 5 0 0 5 5 5 0 NTPase Sigma54_activat PF00158.26 CEH12375.1 - 0.091 12.5 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain G-alpha PF00503.20 CEH12375.1 - 0.098 11.8 0.1 10 5.2 0.0 2.6 3 0 0 3 3 2 0 G-protein alpha subunit SRP54 PF00448.22 CEH12375.1 - 0.43 10.2 3.6 4.8 6.7 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Pox_A32 PF04665.12 CEH12375.1 - 0.62 9.5 5.3 1.4 8.3 0.0 3.0 3 1 1 4 4 4 0 Poxvirus A32 protein ATP19 PF11022.8 CEH12375.1 - 0.76 10.2 0.0 0.76 10.2 0.0 2.6 3 0 0 3 3 2 0 ATP synthase subunit K DivIC PF04977.15 CEH12375.1 - 6 6.7 14.4 1.9 8.3 1.5 2.7 3 0 0 3 3 2 0 Septum formation initiator SelR PF01641.18 CEH12376.1 - 6.5e-48 161.8 0.1 8.2e-48 161.5 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 CEH12376.1 - 0.2 11.9 0.7 0.84 9.9 0.7 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 CEH12376.1 - 1.4 9.0 4.2 12 6.1 0.5 2.2 1 1 2 3 3 3 0 Double zinc ribbon ECH_1 PF00378.20 CEH12377.1 - 3.6e-48 164.1 0.0 4.3e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEH12377.1 - 5.4e-26 91.9 0.1 2.5e-22 79.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CBFD_NFYB_HMF PF00808.23 CEH12378.1 - 1.1e-22 80.0 0.8 1.6e-22 79.6 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEH12378.1 - 0.0011 19.4 0.1 0.0024 18.3 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 CEH12378.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 CEH12378.1 - 0.069 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CENP-X PF09415.10 CEH12378.1 - 0.17 12.2 0.4 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 CENP-S associating Centromere protein X DUF4211 PF13926.6 CEH12379.1 - 3.7e-08 33.6 0.6 9.2e-08 32.3 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) DcrB PF08786.11 CEH12379.1 - 0.039 14.0 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 DcrB RhoGEF PF00621.20 CEH12380.1 - 4.9e-21 75.8 0.0 1.4e-10 41.7 0.0 2.1 2 0 0 2 2 2 2 RhoGEF domain PH PF00169.29 CEH12380.1 - 0.19 12.3 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 PH domain Gly-zipper_Omp PF13488.6 CEH12380.1 - 0.27 11.3 4.4 0.66 10.0 4.4 1.7 1 0 0 1 1 1 0 Glycine zipper DUF732 PF05305.14 CEH12382.1 - 0.013 15.8 1.8 0.018 15.4 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF732) Cofilin_ADF PF00241.20 CEH12383.1 - 1.3e-18 67.0 0.0 1.4e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2052 PF09747.9 CEH12384.1 - 0.29 11.2 10.6 1.2 9.3 10.6 1.8 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) zf-RING_2 PF13639.6 CEH12386.1 - 4.1e-13 49.4 1.5 7.8e-13 48.5 1.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEH12386.1 - 6.8e-11 41.7 0.5 6.8e-11 41.7 0.5 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 CEH12386.1 - 2.5e-07 30.5 0.3 4.5e-07 29.7 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEH12386.1 - 5.8e-07 29.3 0.7 1e-06 28.5 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEH12386.1 - 1.1e-05 25.3 4.4 0.00025 21.0 0.1 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEH12386.1 - 1.2e-05 25.1 0.3 2.1e-05 24.3 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEH12386.1 - 2.5e-05 24.5 2.8 0.00012 22.3 2.8 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.22 CEH12386.1 - 7.2e-05 22.7 0.1 0.0002 21.3 0.1 1.8 1 0 0 1 1 1 1 PA domain zf-C3HC4_3 PF13920.6 CEH12386.1 - 0.00025 20.8 1.8 0.0006 19.6 1.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEH12386.1 - 0.00032 20.5 1.5 0.00062 19.6 1.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEH12386.1 - 0.088 12.9 1.1 0.19 11.8 1.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 CEH12386.1 - 0.18 11.7 1.4 0.35 10.7 1.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 CEH12386.1 - 0.2 11.9 1.8 0.93 9.7 1.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CEH12386.1 - 0.57 9.8 3.0 1.2 8.8 3.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF202 PF02656.15 CEH12388.1 - 7.2e-14 52.0 4.5 7.2e-14 52.0 4.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX2_TM PF02790.15 CEH12388.1 - 0.0069 16.5 0.4 0.11 12.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, transmembrane domain DUF2615 PF11027.8 CEH12388.1 - 1.7 8.8 3.8 0.95 9.6 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Ribosomal_S17 PF00366.20 CEH12389.1 - 3.1e-26 91.3 0.8 4.5e-26 90.7 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 CEH12389.1 - 5.2e-23 81.2 0.0 9.3e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Importin_rep PF18773.1 CEH12389.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Importin 13 repeat Ribosomal_L7Ae PF01248.26 CEH12390.1 - 7.8e-28 96.1 1.2 9.9e-28 95.7 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Chitin_synth_2 PF03142.15 CEH12391.1 - 2.2e-247 821.9 0.0 2.9e-247 821.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CEH12391.1 - 5.7e-87 292.5 0.0 3.5e-86 289.9 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Cornichon PF03311.14 CEH12391.1 - 2.4e-50 169.9 11.8 2.4e-50 169.9 11.8 3.1 3 1 1 4 4 4 1 Cornichon protein Cyt-b5 PF00173.28 CEH12391.1 - 6.1e-15 55.1 0.2 2.3e-09 37.3 0.0 3.6 4 1 0 4 4 4 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 CEH12391.1 - 1.1e-11 45.1 0.0 5e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEH12391.1 - 7.4e-11 42.3 4.4 7.4e-11 42.3 4.4 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CEH12391.1 - 5.3e-08 32.9 0.0 2.3e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEH12391.1 - 0.002 17.6 0.0 0.0058 16.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Mito_carr PF00153.27 CEH12392.1 - 1.2e-54 182.2 5.9 1.4e-19 69.8 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.6 CEH12394.1 - 6e-07 29.6 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.20 CEH12394.1 - 0.039 14.2 0.0 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 PPR repeat PPR_3 PF13812.6 CEH12394.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Pentatricopeptide repeat domain ELYS PF13934.6 CEH12395.1 - 1.9e-17 64.0 0.0 2.9e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly Ras PF00071.22 CEH12396.1 - 3.6e-49 166.5 0.0 4.3e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH12396.1 - 1.2e-29 103.0 0.0 1.8e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH12396.1 - 1.6e-09 37.4 0.0 2.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEH12396.1 - 0.00074 18.9 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEH12396.1 - 0.0017 18.4 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CEH12396.1 - 0.0056 15.9 1.0 1.8 7.6 0.1 2.7 2 1 1 3 3 3 2 G-protein alpha subunit Pox_A32 PF04665.12 CEH12396.1 - 0.023 14.2 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 CEH12396.1 - 0.037 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CEH12396.1 - 0.038 14.4 0.1 0.35 11.3 0.1 2.1 1 1 0 1 1 1 0 RNA helicase DUF5118 PF17162.4 CEH12396.1 - 0.038 13.8 0.1 0.071 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) AAA_24 PF13479.6 CEH12396.1 - 0.045 13.5 0.1 0.1 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CEH12396.1 - 0.066 13.1 0.0 8.8 6.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CEH12396.1 - 0.069 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain STAS PF01740.21 CEH12396.1 - 0.097 12.3 0.0 0.21 11.2 0.0 1.6 1 1 0 1 1 1 0 STAS domain TsaE PF02367.17 CEH12396.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CEH12396.1 - 0.13 12.4 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain DUF1892 PF08987.10 CEH12397.1 - 0.081 13.1 0.1 0.083 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) RRM_1 PF00076.22 CEH12398.1 - 3.5e-28 97.2 0.0 3e-16 59.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEH12398.1 - 2.7e-05 24.2 0.0 7.5e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 CEH12398.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CEH12398.1 - 0.1 12.7 0.2 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 RNA recognition motif zf_CCCH_4 PF18345.1 CEH12400.1 - 3.4e-05 23.8 4.0 6.8e-05 22.8 4.0 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CEH12400.1 - 0.00016 21.5 1.2 0.00027 20.8 1.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEH12400.1 - 0.00023 20.9 1.4 0.00047 19.9 1.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger ABC_tran PF00005.27 CEH12401.1 - 2.6e-61 206.1 0.0 5.2e-32 111.2 0.0 3.7 3 1 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 CEH12401.1 - 8e-55 186.4 15.2 8.4e-28 97.8 2.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CEH12401.1 - 3.2e-18 66.0 0.7 1.3e-09 37.9 0.1 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CEH12401.1 - 1e-09 37.7 1.6 0.0014 17.5 0.0 4.4 4 1 0 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 CEH12401.1 - 1.4e-08 34.8 0.0 0.0067 16.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CEH12401.1 - 1.9e-08 33.9 3.9 0.0026 17.5 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CEH12401.1 - 2.2e-07 31.2 0.2 0.055 13.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 CEH12401.1 - 6.7e-07 29.1 0.0 0.016 14.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 CEH12401.1 - 2.4e-06 27.8 0.0 0.044 13.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CEH12401.1 - 1.3e-05 25.8 0.1 0.23 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CEH12401.1 - 1.4e-05 25.1 0.0 0.58 9.9 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 CEH12401.1 - 1.5e-05 24.6 0.2 0.083 12.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_15 PF13175.6 CEH12401.1 - 3.1e-05 23.9 0.0 0.27 10.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 CEH12401.1 - 0.00011 22.7 0.1 0.22 12.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain DUF3987 PF13148.6 CEH12401.1 - 0.00016 20.8 1.1 0.0058 15.7 1.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_16 PF13191.6 CEH12401.1 - 0.00039 20.9 8.9 0.12 12.7 0.3 3.4 2 2 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 CEH12401.1 - 0.00043 19.5 0.1 0.14 11.3 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.14 CEH12401.1 - 0.00044 20.3 0.1 0.84 9.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CEH12401.1 - 0.0026 18.2 0.1 1.8 9.0 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CEH12401.1 - 0.0029 16.8 0.1 0.95 8.6 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 CEH12401.1 - 0.0041 16.9 7.2 0.16 11.7 0.0 3.7 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.6 CEH12401.1 - 0.0079 16.4 2.9 3.2 8.1 0.5 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 CEH12401.1 - 0.0083 16.2 0.0 11 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CEH12401.1 - 0.0095 16.3 0.0 7.6 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 CEH12401.1 - 0.0098 15.2 1.2 0.55 9.5 0.1 3.0 3 0 0 3 3 3 1 Zeta toxin ATP-synt_ab PF00006.25 CEH12401.1 - 0.011 15.4 2.6 6.9 6.3 0.0 3.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 CEH12401.1 - 0.015 15.4 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CEH12401.1 - 0.023 14.5 0.2 2.9 7.6 0.0 3.1 3 1 1 4 4 3 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 CEH12401.1 - 0.029 14.1 0.0 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CEH12401.1 - 0.041 13.6 0.2 3.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 CEH12401.1 - 0.056 13.4 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 CEH12401.1 - 0.056 13.7 1.4 9.8 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 CEH12401.1 - 0.057 13.8 8.2 1.3 9.4 0.0 4.2 5 1 0 5 5 3 0 AAA domain NACHT PF05729.12 CEH12401.1 - 0.08 12.9 5.0 2.1 8.2 0.0 3.8 5 0 0 5 5 3 0 NACHT domain Roc PF08477.13 CEH12401.1 - 0.11 12.7 0.0 26 5.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase bPH_3 PF14470.6 CEH12402.1 - 0.067 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain DUF4503 PF14951.6 CEH12402.1 - 0.073 11.5 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Ashwin PF15323.6 CEH12402.1 - 0.41 10.6 2.1 0.76 9.8 2.1 1.4 1 0 0 1 1 1 0 Developmental protein Med3 PF11593.8 CEH12402.1 - 1.4 8.0 15.7 2.1 7.5 15.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RAP1 PF07218.11 CEH12402.1 - 7.3 4.7 6.5 9.9 4.3 6.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.16 CEH12403.1 - 1.2e-07 31.1 39.9 1.2e-07 31.1 39.9 2.6 2 2 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 CEH12403.1 - 6.1e-07 28.3 26.5 1.6e-05 23.7 26.5 2.3 1 1 0 1 1 1 1 MFS/sugar transport protein DUF2892 PF11127.8 CEH12403.1 - 0.56 10.3 0.0 0.56 10.3 0.0 4.8 6 0 0 6 6 6 0 Protein of unknown function (DUF2892) ADH_zinc_N_2 PF13602.6 CEH12404.1 - 3e-08 34.8 0.0 1.1e-07 33.0 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CEH12404.1 - 4.3e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH12404.1 - 0.0057 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DPBB_1 PF03330.18 CEH12405.1 - 0.0019 18.5 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Mito_carr PF00153.27 CEH12406.1 - 2e-48 162.3 5.7 4.9e-16 58.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 CEH12406.1 - 0.012 15.8 0.0 2.8 8.2 0.0 2.8 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF2620 PF10941.8 CEH12406.1 - 0.12 12.5 2.2 0.7 10.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF2620 KCH PF16944.5 CEH12407.1 - 1.2e-85 287.3 14.0 1.5e-85 287.0 14.0 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF2516 PF10724.9 CEH12407.1 - 3.6 7.9 6.8 3.8 7.8 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) CHRD PF07452.12 CEH12409.1 - 1.7e-30 106.4 0.3 1.2e-15 58.5 0.2 2.4 2 0 0 2 2 2 2 CHRD domain Imm31 PF15591.6 CEH12409.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 31 TRAPP PF04051.16 CEH12409.1 - 0.2 11.4 0.0 1.4 8.7 0.0 2.0 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component PTH2 PF01981.16 CEH12410.1 - 4.4e-08 33.4 0.1 1.2e-07 32.1 0.1 1.7 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Zein-binding PF04576.15 CEH12410.1 - 0.056 13.7 2.1 0.065 13.5 0.2 2.1 2 0 0 2 2 2 0 Zein-binding Ribosomal_60s PF00428.19 CEH12410.1 - 6.5 7.4 9.2 19 5.9 0.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein TCTP PF00838.17 CEH12411.1 - 9.3e-71 237.5 0.8 1e-70 237.4 0.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Cas9_b_hairpin PF17893.1 CEH12411.1 - 0.069 13.0 0.1 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain MFS_1 PF07690.16 CEH12412.1 - 4.1e-34 118.0 38.6 2.5e-32 112.2 34.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH12412.1 - 6.8e-12 45.0 9.6 6.8e-12 45.0 9.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Mem_trans PF03547.18 CEH12412.1 - 7.1e-05 21.4 0.0 0.00095 17.7 0.0 2.1 2 0 0 2 2 2 1 Membrane transport protein DUF1682 PF07946.14 CEH12412.1 - 0.065 12.4 3.0 0.11 11.7 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_M50 PF02163.22 CEH12412.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M50 CPSF100_C PF13299.6 CEH12412.1 - 4.4 7.5 5.9 2.9 8.1 0.2 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal U1snRNP70_N PF12220.8 CEH12412.1 - 9.1 7.0 9.0 9.5 6.9 6.4 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Abhydrolase_6 PF12697.7 CEH12413.1 - 1.8e-10 41.8 1.3 1.8e-10 41.8 1.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family MFS_1 PF07690.16 CEH12414.1 - 1.9e-16 59.9 20.5 5.3e-15 55.2 6.7 2.7 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH12414.1 - 6.8e-06 25.2 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter Palm_thioest PF02089.15 CEH12415.1 - 2.2e-81 273.3 0.0 2.7e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 CEH12415.1 - 0.0052 16.2 0.0 0.014 14.7 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 CEH12415.1 - 0.0067 16.1 0.1 0.19 11.3 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold ox_reductase_C PF08635.10 CEH12416.1 - 4.3e-73 243.6 0.1 6.1e-73 243.1 0.1 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 CEH12416.1 - 3.3e-24 86.0 0.0 7.8e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CEH12416.1 - 0.019 15.0 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Ank_2 PF12796.7 CEH12417.1 - 2.2e-17 63.4 5.1 9.8e-07 29.3 0.1 7.1 5 2 2 7 7 7 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEH12417.1 - 3.5e-14 53.0 0.4 0.0027 18.3 0.0 6.4 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEH12417.1 - 4.9e-11 42.6 2.2 4.1 7.8 0.0 8.0 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 CEH12417.1 - 4e-10 39.7 4.1 0.014 15.9 0.0 7.6 8 0 0 8 8 8 2 Ankyrin repeat Ank_3 PF13606.6 CEH12417.1 - 1.2e-09 37.6 2.2 0.034 14.7 0.0 7.7 8 0 0 8 8 8 2 Ankyrin repeat adh_short_C2 PF13561.6 CEH12418.1 - 9.9e-33 113.6 5.9 2.5e-19 69.7 0.2 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH12418.1 - 2.3e-27 95.7 5.6 5.1e-26 91.3 5.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH12418.1 - 2.2e-05 24.5 5.5 8.7e-05 22.5 0.8 2.3 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CEH12418.1 - 0.014 14.9 3.6 0.56 9.6 3.6 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 CEH12418.1 - 0.064 13.2 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF4536 PF15055.6 CEH12418.1 - 0.45 10.8 2.6 0.87 9.9 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) MDM31_MDM32 PF08118.11 CEH12419.1 - 5.8e-178 592.8 0.0 4.3e-177 590.0 0.0 2.0 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins FGase PF05013.12 CEH12419.1 - 0.0048 17.1 0.5 0.07 13.3 0.2 2.2 2 0 0 2 2 2 1 N-formylglutamate amidohydrolase LisH PF08513.11 CEH12420.1 - 1.4e-05 24.8 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 LisH P5CR_dimer PF14748.6 CEH12420.1 - 0.14 12.4 1.2 0.35 11.1 1.2 1.6 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation ArgJ PF01960.18 CEH12421.1 - 8.3e-133 442.7 0.0 1.1e-132 442.4 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Ribosomal_S13 PF00416.22 CEH12422.1 - 9.7e-24 84.2 0.0 1.5e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CEH12422.1 - 0.011 14.5 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) MWFE PF15879.5 CEH12423.1 - 2.1e-22 79.0 0.9 2.6e-22 78.7 0.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Acyltransferase PF01553.21 CEH12424.1 - 2.4e-19 69.3 0.0 3.4e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Glyco_hydro_16 PF00722.21 CEH12425.1 - 1.4e-36 125.6 0.6 2e-36 125.1 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.6 CEH12425.1 - 0.014 15.6 0.2 0.027 14.6 0.1 1.6 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Pilin PF00114.19 CEH12425.1 - 0.07 14.1 2.0 0.1 13.5 0.2 2.1 2 1 0 2 2 2 0 Pilin (bacterial filament) Laminin_G_2 PF02210.24 CEH12425.1 - 0.099 13.2 0.0 0.24 12.0 0.0 1.7 1 1 1 2 2 2 0 Laminin G domain zf-C2H2 PF00096.26 CEH12428.1 - 8.6e-06 25.9 9.7 0.013 16.0 1.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 CEH12428.1 - 0.073 13.7 0.5 9.3 7.0 0.0 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 CEH12428.1 - 0.15 12.5 12.8 0.18 12.3 2.0 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEH12428.1 - 0.41 11.6 7.4 6.7 7.8 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger F-box-like PF12937.7 CEH12429.1 - 1.4e-09 37.7 1.0 1.4e-09 37.7 1.0 2.7 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 CEH12429.1 - 1.6e-07 31.5 2.6 3.3 8.3 0.0 6.9 5 3 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEH12429.1 - 0.0002 21.1 11.0 1.2 9.3 0.0 7.4 9 0 0 9 9 9 2 Leucine Rich repeat F-box PF00646.33 CEH12429.1 - 0.0011 18.8 0.8 0.45 10.5 0.2 3.6 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 CEH12429.1 - 0.011 16.1 5.5 72 4.5 0.0 6.3 7 0 0 7 7 7 0 Leucine Rich Repeat STAS_2 PF13466.6 CEH12429.1 - 0.04 14.3 1.3 1.6 9.1 0.0 3.2 1 1 1 2 2 2 0 STAS domain PP2C PF00481.21 CEH12430.1 - 1.7e-66 224.5 0.2 1.3e-51 175.8 0.4 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Pkinase_fungal PF17667.1 CEH12431.1 - 6.5e-06 25.2 0.4 0.039 12.7 0.1 3.6 3 2 0 3 3 3 3 Fungal protein kinase DUF5315 PF17242.2 CEH12431.1 - 0.016 15.0 0.3 2.2 8.2 0.1 3.6 3 0 0 3 3 3 0 Disordered region of unknown function (DUF5315) B9-C2 PF07162.11 CEH12432.1 - 0.066 13.4 0.1 0.091 13.0 0.1 1.2 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein GN3L_Grn1 PF08701.11 CEH12433.1 - 9.1e-24 83.4 19.3 9.1e-24 83.4 19.3 3.7 3 1 0 3 3 3 1 GNL3L/Grn1 putative GTPase SDA1 PF05285.12 CEH12433.1 - 0.0046 16.4 26.7 0.0046 16.4 26.7 3.6 3 1 0 3 3 3 2 SDA1 zf-CCHC PF00098.23 CEH12434.1 - 8.3e-30 101.5 48.3 1.9e-07 30.8 2.3 6.6 6 1 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 CEH12434.1 - 1.8e-09 37.1 30.3 0.0066 16.2 0.6 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.6 CEH12434.1 - 0.029 14.3 31.5 1.4 8.9 0.3 6.0 2 2 3 5 5 5 0 Zinc knuckle zf-CCHC_2 PF13696.6 CEH12434.1 - 0.063 13.1 40.5 0.28 11.1 2.4 6.5 6 0 0 6 6 6 0 Zinc knuckle zf-CCHC_5 PF14787.6 CEH12434.1 - 0.067 12.9 0.8 0.067 12.9 0.8 6.1 5 1 1 6 6 6 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 CEH12434.1 - 0.26 11.7 0.0 0.26 11.7 0.0 3.7 3 1 1 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G CHCH PF06747.13 CEH12435.1 - 0.0013 18.8 3.3 0.0013 18.8 3.3 2.3 2 0 0 2 2 2 1 CHCH domain CX9C PF16860.5 CEH12435.1 - 0.025 14.6 10.4 0.23 11.5 1.8 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 CEH12435.1 - 1.4 9.3 10.0 8.1 6.8 0.7 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 MMR_HSR1_Xtn PF16897.5 CEH12436.1 - 6.2e-40 135.5 0.7 3.1e-39 133.2 0.3 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CEH12436.1 - 1.4e-20 73.1 0.0 2.7e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CEH12436.1 - 1.6e-20 73.3 0.0 3.8e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH12436.1 - 4.3e-09 36.1 0.2 1.4e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CEH12436.1 - 0.035 14.2 0.3 1.4 9.0 0.0 2.4 1 1 1 2 2 2 0 Dynamin family MeaB PF03308.16 CEH12436.1 - 0.059 12.3 0.5 0.13 11.2 0.5 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Slu7 PF11708.8 CEH12437.1 - 7.7e-88 294.7 17.0 7.7e-88 294.7 17.0 2.6 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor EF-hand_1 PF00036.32 CEH12438.1 - 3.2e-27 92.0 13.9 1.3e-07 30.6 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEH12438.1 - 2.5e-21 75.9 7.7 3.1e-12 46.8 1.6 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEH12438.1 - 1.8e-20 71.1 9.6 2.2e-05 24.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CEH12438.1 - 7e-18 63.2 14.9 7.2e-06 25.3 0.9 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CEH12438.1 - 4.1e-11 42.6 15.7 0.0097 15.7 0.3 4.3 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CEH12438.1 - 3.4e-05 24.1 0.0 0.037 14.4 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEH12438.1 - 0.00012 21.9 7.4 0.03 14.3 0.5 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEH12438.1 - 0.00014 22.1 0.1 1.1 9.6 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain VCBS PF13517.6 CEH12438.1 - 0.1 13.2 1.0 20 5.9 0.2 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella ABC_tran PF00005.27 CEH12439.1 - 3.3e-38 131.3 0.6 9.6e-19 68.3 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CEH12439.1 - 2.9e-11 43.7 3.2 0.0027 17.6 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEH12439.1 - 1.3e-07 31.3 0.1 0.12 11.8 0.0 3.9 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEH12439.1 - 3.4e-06 26.7 0.3 0.088 12.6 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CEH12439.1 - 4.5e-05 24.1 4.7 0.35 11.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CEH12439.1 - 7.1e-05 22.8 0.1 0.05 13.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 CEH12439.1 - 7.2e-05 23.2 0.3 0.41 11.1 0.0 3.4 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 CEH12439.1 - 7.4e-05 22.8 0.2 0.75 9.9 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_28 PF13521.6 CEH12439.1 - 0.00051 20.3 2.3 0.86 9.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 CEH12439.1 - 0.00075 19.5 0.2 1.1 9.2 0.0 2.9 3 0 0 3 3 2 2 NACHT domain NTPase_1 PF03266.15 CEH12439.1 - 0.00091 19.2 0.0 0.12 12.3 0.0 3.2 3 0 0 3 3 3 1 NTPase AAA_5 PF07728.14 CEH12439.1 - 0.0013 18.7 0.1 4.8 7.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CEH12439.1 - 0.0095 16.3 0.0 5.4 7.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 CEH12439.1 - 0.0099 16.3 10.4 0.086 13.2 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CEH12439.1 - 0.0099 16.1 0.8 6.4 7.1 0.2 3.3 2 2 0 2 2 2 0 AAA domain DUF815 PF05673.13 CEH12439.1 - 0.015 14.5 0.1 0.7 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CEH12439.1 - 0.018 14.6 0.0 0.77 9.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CEH12439.1 - 0.022 14.5 0.1 2.5 7.8 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 CEH12439.1 - 0.022 14.9 7.5 1.4 9.0 0.1 4.1 3 2 0 3 3 3 0 AAA domain AAA_25 PF13481.6 CEH12439.1 - 0.025 14.2 4.3 1.6 8.3 0.9 3.5 2 2 0 2 2 2 0 AAA domain TsaE PF02367.17 CEH12439.1 - 0.049 13.6 0.0 3.1 7.8 0.0 2.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 CEH12439.1 - 0.053 13.8 0.1 0.28 11.4 0.0 2.4 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit RuvB_N PF05496.12 CEH12439.1 - 0.076 12.8 0.2 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 CEH12439.1 - 0.076 12.6 0.2 6 6.5 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 CEH12439.1 - 0.1 11.7 0.0 4.7 6.3 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_15 PF13175.6 CEH12439.1 - 0.1 12.3 0.1 23 4.6 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 CEH12439.1 - 0.11 11.9 0.1 3.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 CEH12439.1 - 0.16 12.2 0.0 6.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran_Xtn PF12848.7 CEH12439.1 - 1 9.4 11.4 0.066 13.3 5.0 2.4 3 0 0 3 3 1 0 ABC transporter PhzC-PhzF PF02567.16 CEH12441.1 - 6.1e-39 134.2 0.0 1.3e-38 133.2 0.0 1.4 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 CEH12441.1 - 0.0031 16.6 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Proline racemase UDPGP PF01704.18 CEH12442.1 - 2.7e-197 655.4 0.2 3.1e-197 655.2 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Aldedh PF00171.22 CEH12443.1 - 1.8e-105 353.1 0.1 2.1e-105 352.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA PF00004.29 CEH12444.1 - 9e-53 178.2 0.0 2.5e-39 134.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEH12444.1 - 4.9e-10 39.0 0.2 1.1e-09 37.9 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 CEH12444.1 - 1.7e-09 37.3 0.3 7.6e-08 32.0 0.0 2.8 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 CEH12444.1 - 5.6e-09 36.4 0.0 0.00029 21.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEH12444.1 - 1.8e-08 34.9 0.0 0.0094 16.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 CEH12444.1 - 2.1e-08 34.5 0.0 1.2e-05 25.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CEH12444.1 - 1.3e-07 31.7 0.1 0.0019 18.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEH12444.1 - 2.7e-07 30.5 0.1 0.0086 15.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CEH12444.1 - 6.8e-07 29.2 0.1 0.021 14.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CEH12444.1 - 1.2e-06 28.7 0.0 0.049 13.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CEH12444.1 - 1.7e-06 27.6 0.3 0.0066 15.8 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CEH12444.1 - 2e-06 27.3 0.0 0.053 12.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 CEH12444.1 - 6.4e-06 26.7 0.0 0.022 15.3 0.0 3.3 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 CEH12444.1 - 1.2e-05 25.6 0.0 0.059 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 CEH12444.1 - 2e-05 24.4 0.1 0.083 12.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 CEH12444.1 - 6.2e-05 22.8 0.0 0.88 9.3 0.0 3.2 3 0 0 3 3 3 2 Sigma-54 interaction domain NACHT PF05729.12 CEH12444.1 - 9.2e-05 22.4 1.4 0.24 11.3 0.0 3.5 4 0 0 4 4 3 1 NACHT domain TsaE PF02367.17 CEH12444.1 - 9.5e-05 22.4 0.0 0.08 12.9 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CEH12444.1 - 9.9e-05 22.0 0.1 0.39 10.3 0.1 3.0 3 0 0 3 3 2 2 AAA domain ATPase PF06745.13 CEH12444.1 - 0.00011 21.7 0.1 0.0081 15.5 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_11 PF13086.6 CEH12444.1 - 0.00013 21.9 0.1 0.47 10.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CEH12444.1 - 0.00014 21.7 0.0 0.49 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CEH12444.1 - 0.00024 21.1 0.0 0.54 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 CEH12444.1 - 0.00029 20.4 0.0 0.35 10.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_7 PF12775.7 CEH12444.1 - 0.00034 20.2 0.9 0.029 13.9 0.0 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 CEH12444.1 - 0.00039 21.0 0.4 0.11 13.0 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_3 PF07726.11 CEH12444.1 - 0.00085 19.2 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 CEH12444.1 - 0.0019 17.3 0.0 0.91 8.6 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 CEH12444.1 - 0.003 17.8 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CEH12444.1 - 0.0041 17.5 0.4 1.3 9.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CEH12444.1 - 0.0095 15.9 0.3 17 5.3 0.0 3.4 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 CEH12444.1 - 0.0098 15.1 0.1 3.6 6.7 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain ResIII PF04851.15 CEH12444.1 - 0.015 15.4 0.0 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CEH12444.1 - 0.015 14.6 0.1 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 CEH12444.1 - 0.015 15.8 0.1 5.4 7.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain DAP3 PF10236.9 CEH12444.1 - 0.034 13.3 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CEH12444.1 - 0.1 12.4 0.2 7.5 6.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.10 CEH12444.1 - 0.11 12.0 0.1 3 7.2 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CEH12444.1 - 0.13 11.5 0.1 3.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Hydin_ADK PF17213.3 CEH12444.1 - 0.14 12.4 0.6 2.1 8.6 0.2 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Proteasome PF00227.26 CEH12445.1 - 5.8e-42 143.3 0.1 6.6e-42 143.1 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Myb_DNA-binding PF00249.31 CEH12446.1 - 1.1e-11 44.7 1.0 2.5e-11 43.6 1.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH12446.1 - 7.5e-06 26.1 0.7 1.6e-05 25.1 0.7 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ERM PF00769.19 CEH12446.1 - 0.05 13.4 5.5 0.22 11.3 5.5 2.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family COX14 PF14880.6 CEH12448.1 - 0.0025 17.6 1.0 0.0025 17.6 1.0 1.6 2 0 0 2 2 2 1 Cytochrome oxidase c assembly GDPD PF03009.17 CEH12449.1 - 1.8e-31 109.9 0.0 2.8e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 CEH12449.1 - 0.00032 21.0 1.3 0.00093 19.6 1.3 1.9 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PPI_Ypi1 PF07491.11 CEH12450.1 - 4.2e-23 80.9 7.8 4.2e-23 80.9 7.8 3.4 2 1 0 2 2 2 1 Protein phosphatase inhibitor LAP1C PF05609.12 CEH12450.1 - 2.4 7.2 13.3 3.2 6.7 13.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DNA_pol_phi PF04931.13 CEH12450.1 - 9.2 4.2 9.0 10 4.1 9.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi TPR_21 PF09976.9 CEH12452.1 - 0.17 11.5 0.1 0.34 10.6 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain RNase_H PF00075.24 CEH12454.1 - 1e-05 25.7 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 RNase H Complex1_LYR PF05347.15 CEH12456.1 - 6.1e-08 32.6 0.1 1.4e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CEH12456.1 - 0.00037 21.2 0.1 0.00079 20.1 0.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Ribosomal_L31 PF01197.18 CEH12456.1 - 0.017 15.3 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L31 ASD2 PF08687.11 CEH12456.1 - 0.083 12.4 0.0 0.083 12.4 0.0 2.1 3 0 0 3 3 3 0 Apx/Shroom domain ASD2 3-HAO PF06052.12 CEH12457.1 - 2.2e-57 192.9 0.0 2.6e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 CEH12457.1 - 2.5e-06 27.1 0.0 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CEH12457.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 CEH12457.1 - 0.048 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Adaptin_N PF01602.20 CEH12458.1 - 1.1e-121 407.0 10.4 1.5e-121 406.6 10.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CEH12458.1 - 1.5e-42 144.3 0.1 4.9e-42 142.7 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 CEH12458.1 - 1.6e-10 41.3 0.0 4.4e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CEH12458.1 - 0.0013 18.8 2.6 0.01 15.9 0.0 2.9 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Leo1 PF04004.13 CEH12459.1 - 4.2e-39 134.0 0.2 1.2e-38 132.5 0.2 1.8 1 0 0 1 1 1 1 Leo1-like protein Glyco_hydro_cc PF11790.8 CEH12460.1 - 1.6e-49 168.6 1.4 1.8e-49 168.5 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.13 CEH12460.1 - 0.0026 16.8 0.0 0.0032 16.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 CEH12460.1 - 0.026 14.0 0.3 0.037 13.4 0.3 1.4 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Pmp3 PF01679.17 CEH12461.1 - 2.8e-17 62.6 9.5 3.2e-17 62.5 9.5 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pmp3 PF01679.17 CEH12462.1 - 2.5e-22 78.8 8.4 3e-22 78.6 8.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Fungal_trans PF04082.18 CEH12466.1 - 7e-11 41.7 0.2 1.1e-10 41.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH12466.1 - 1.3e-07 31.6 6.6 3.7e-07 30.1 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RanBP PF00641.18 CEH12466.1 - 0.28 10.5 1.9 0.94 8.9 1.9 1.9 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others MFS_1 PF07690.16 CEH12467.1 - 5.9e-43 147.1 36.0 1.3e-41 142.7 36.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CEH12467.1 - 2.4e-14 52.7 17.0 3.6e-14 52.1 17.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) VHS PF00790.19 CEH12469.1 - 1.4e-37 128.7 0.2 3.7e-37 127.3 0.0 1.8 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 CEH12469.1 - 1.3e-15 57.2 5.3 2.4e-15 56.4 5.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 CEH12469.1 - 2.5e-06 27.0 5.9 0.016 15.1 2.0 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif Hist_deacetyl PF00850.19 CEH12470.1 - 9.9e-81 271.6 0.0 1.3e-80 271.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain WD40 PF00400.32 CEH12471.1 - 1e-40 136.9 11.8 1.6e-08 35.0 0.4 7.4 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH12471.1 - 1.9e-13 50.5 0.1 0.00092 19.5 0.0 5.2 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEH12471.1 - 7.1e-09 35.1 0.1 0.0055 15.7 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CEH12471.1 - 0.00016 21.1 0.1 0.017 14.5 0.0 2.4 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 CEH12471.1 - 0.0038 15.8 0.0 0.022 13.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 CEH12471.1 - 0.0097 15.3 0.0 3.1 7.0 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 CEH12471.1 - 0.03 13.0 0.1 8.5 4.9 0.0 2.9 2 2 1 3 3 3 0 Nucleoporin Nup120/160 DpaA_N PF16924.5 CEH12471.1 - 0.12 12.5 0.0 0.75 9.9 0.0 2.0 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain Acyl-CoA_dh_N PF02771.16 CEH12474.1 - 6.6e-26 91.2 0.0 1.1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 CEH12474.1 - 8.5e-25 87.7 0.0 1.5e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEH12474.1 - 1.8e-20 72.9 0.0 3.5e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEH12474.1 - 4.1e-09 36.8 0.5 1.5e-08 35.0 0.3 2.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Rit1_C PF17184.4 CEH12475.1 - 2.3e-39 135.5 0.0 9.7e-31 107.2 0.0 2.1 1 1 1 2 2 2 2 Rit1 N-terminal domain zf-U1 PF06220.12 CEH12476.1 - 8.4e-19 67.1 6.9 1.1e-18 66.7 6.9 1.2 1 0 0 1 1 1 1 U1 zinc finger Flavokinase PF01687.17 CEH12477.1 - 1.3e-25 89.8 0.0 1.8e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Cullin_binding PF03556.15 CEH12478.1 - 1.5e-32 112.6 0.2 2.1e-32 112.1 0.2 1.2 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 CEH12478.1 - 1.6e-08 34.2 0.2 3e-08 33.4 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain Cu-oxidase_3 PF07732.15 CEH12479.1 - 9.2e-32 109.6 0.7 2.3e-31 108.3 0.7 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CEH12479.1 - 8.8e-20 70.8 13.4 5.8e-14 52.0 5.8 3.7 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 CEH12479.1 - 7.3e-19 68.4 0.0 1.8e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase HMG_box PF00505.19 CEH12480.1 - 3.5e-19 69.0 13.2 4.6e-11 43.0 2.3 3.2 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CEH12480.1 - 7.5e-19 68.1 8.4 7.4e-09 36.1 2.2 2.8 2 0 0 2 2 2 2 HMG-box domain DUF1561 PF07598.11 CEH12480.1 - 0.0017 16.7 0.0 0.0024 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1561) YABBY PF04690.13 CEH12480.1 - 0.3 11.7 10.9 0.13 12.8 7.1 2.3 1 1 1 2 2 2 0 YABBY protein Zn_clus PF00172.18 CEH12481.1 - 0.0026 17.8 14.6 0.0031 17.6 10.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 CEH12482.1 - 4.1e-40 137.8 0.0 4.9e-22 78.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain SWIB PF02201.18 CEH12482.1 - 3.3e-23 81.3 0.0 7.9e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase_Tyr PF07714.17 CEH12482.1 - 1.5e-13 50.6 0.0 1.2e-10 41.1 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase DEK_C PF08766.11 CEH12482.1 - 9.6e-05 22.2 0.1 0.0002 21.2 0.1 1.6 1 0 0 1 1 1 1 DEK C terminal domain APH PF01636.23 CEH12482.1 - 0.014 15.4 0.3 0.088 12.7 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CEH12482.1 - 0.17 11.2 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like CRAL_TRIO PF00650.20 CEH12483.1 - 4.3e-35 120.8 0.0 7.7e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEH12483.1 - 7.6e-10 38.8 0.1 7.6e-10 38.8 0.1 2.5 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain YacG PF03884.14 CEH12483.1 - 0.13 12.0 0.3 0.3 10.9 0.3 1.5 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG Isochorismatase PF00857.20 CEH12484.1 - 4.1e-29 102.0 0.1 7.7e-29 101.1 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family Iso_dh PF00180.20 CEH12485.1 - 1.4e-100 336.8 0.0 1.8e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase fn3_2 PF16893.5 CEH12486.1 - 1.5e-34 118.0 0.1 2.7e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 CEH12486.1 - 6.8e-26 90.0 0.1 1.3e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 CEH12486.1 - 4.8e-07 30.1 0.0 7.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CEH12486.1 - 2.6e-06 27.3 0.0 2.2e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CEH12486.1 - 2.6e-05 24.5 0.0 0.00018 21.8 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 CEH12486.1 - 0.00017 21.7 0.0 0.00044 20.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 CEH12486.1 - 0.0015 18.9 0.0 0.004 17.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain NmrA PF05368.13 CEH12487.1 - 1.6e-07 31.2 0.0 1.7e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 CEH12487.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Ysc84 PF04366.12 CEH12489.1 - 1.2e-35 122.1 0.0 2.7e-35 120.9 0.0 1.7 1 0 0 1 1 1 1 Las17-binding protein actin regulator DUF4683 PF15735.5 CEH12489.1 - 0.19 11.3 0.7 0.36 10.4 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) Mob1_phocein PF03637.17 CEH12490.1 - 2.4e-61 206.7 0.4 3.2e-61 206.2 0.4 1.1 1 0 0 1 1 1 1 Mob1/phocein family Rhodanese PF00581.20 CEH12491.1 - 1.9e-05 25.1 0.0 4.6e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain zf-CCHC PF00098.23 CEH12493.1 - 2.1e-07 30.7 0.9 3.5e-07 30.0 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle Phage_Mu_Gam PF07352.12 CEH12493.1 - 0.094 12.6 0.4 0.15 11.9 0.4 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Retrotrans_gag PF03732.17 CEH12493.1 - 0.1 12.9 1.4 4.3 7.7 0.0 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein MerR-DNA-bind PF09278.11 CEH12493.1 - 0.84 10.2 0.1 0.84 10.2 0.1 2.6 2 0 0 2 2 2 0 MerR, DNA binding SR-25 PF10500.9 CEH12495.1 - 0.058 13.0 3.6 0.19 11.3 3.6 1.9 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Myb_DNA-binding PF00249.31 CEH12495.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain GATase PF00117.28 CEH12496.1 - 4.7e-05 23.2 0.4 0.00019 21.3 0.1 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Far-17a_AIG1 PF04750.14 CEH12496.1 - 0.36 10.1 0.7 1.1 8.5 0.7 1.6 1 1 0 1 1 1 0 FAR-17a/AIG1-like protein YEATS PF03366.16 CEH12497.1 - 2.3e-35 120.4 0.0 3.8e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 YEATS family Amino_oxidase PF01593.24 CEH12499.1 - 2.1e-19 70.2 2.0 3e-13 49.9 0.0 3.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEH12499.1 - 3.5e-14 52.8 0.0 9.4e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEH12499.1 - 1.5e-05 24.8 0.2 1.5e-05 24.8 0.2 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEH12499.1 - 4.4e-05 23.5 0.1 0.043 13.8 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CEH12499.1 - 8.5e-05 21.8 0.3 0.00019 20.7 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CEH12499.1 - 0.004 17.7 0.3 0.012 16.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEH12499.1 - 0.007 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEH12499.1 - 0.015 14.5 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 CEH12499.1 - 0.018 13.8 0.1 0.094 11.4 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 CEH12499.1 - 0.065 12.3 0.2 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2063 PF09836.9 CEH12501.1 - 0.094 13.0 0.4 0.33 11.2 0.2 2.1 2 0 0 2 2 2 0 Putative DNA-binding domain TMP_2 PF06791.13 CEH12501.1 - 0.22 11.2 6.2 0.52 10.0 6.2 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF3439 PF11921.8 CEH12501.1 - 1 9.3 3.6 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) AAA_5 PF07728.14 CEH12502.1 - 2.7e-114 377.3 0.0 1.3e-20 73.8 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CEH12502.1 - 1.9e-47 159.8 11.2 1.1e-15 57.7 0.1 6.8 6 0 0 6 6 5 3 Midasin AAA lid domain AAA PF00004.29 CEH12502.1 - 2.8e-27 95.7 0.0 0.0092 16.4 0.0 7.6 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 CEH12502.1 - 1e-26 93.3 0.0 2.5e-07 30.6 0.0 7.7 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 CEH12502.1 - 3.9e-25 88.0 0.3 5.8e-24 84.2 0.0 3.3 3 1 0 3 3 2 1 Midasin AAA lid domain AAA_7 PF12775.7 CEH12502.1 - 2.1e-22 79.5 0.0 0.00011 21.8 0.0 7.4 7 0 0 7 7 7 4 P-loop containing dynein motor region Dynein_heavy PF03028.15 CEH12502.1 - 2.6e-18 66.2 0.0 0.00026 21.0 0.0 7.4 9 0 0 9 9 6 4 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 CEH12502.1 - 8.4e-18 65.2 0.5 0.22 12.0 0.0 7.7 7 0 0 7 7 6 4 AAA domain AAA_6 PF12774.7 CEH12502.1 - 2.5e-17 62.8 0.1 0.0083 15.1 0.1 7.6 8 0 0 8 8 7 4 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 CEH12502.1 - 3.7e-17 62.7 5.8 0.0078 16.0 0.0 7.9 6 2 0 6 6 5 3 AAA domain AAA_33 PF13671.6 CEH12502.1 - 3.1e-16 59.8 3.7 0.0012 19.1 0.1 7.8 7 0 0 7 7 6 2 AAA domain TsaE PF02367.17 CEH12502.1 - 5.3e-16 58.8 3.1 0.23 11.5 0.0 7.2 7 0 0 7 7 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CEH12502.1 - 5.3e-16 59.1 7.6 0.028 14.7 0.1 8.5 8 1 0 8 8 6 4 AAA domain AAA_16 PF13191.6 CEH12502.1 - 7.2e-15 55.8 67.1 0.00019 21.8 2.7 12.8 12 3 0 12 12 9 6 AAA ATPase domain Sigma54_activat PF00158.26 CEH12502.1 - 1.7e-14 53.9 0.0 0.0034 17.1 0.0 6.4 7 0 0 7 7 7 3 Sigma-54 interaction domain ABC_tran PF00005.27 CEH12502.1 - 6.8e-14 52.5 0.0 0.15 12.6 0.0 6.7 6 0 0 6 6 6 3 ABC transporter AAA_28 PF13521.6 CEH12502.1 - 7.2e-12 45.9 5.1 0.96 9.7 0.0 8.8 8 0 0 8 8 7 2 AAA domain Zeta_toxin PF06414.12 CEH12502.1 - 7.8e-12 44.9 1.6 0.081 12.2 0.0 6.6 6 0 0 6 6 6 2 Zeta toxin T2SSE PF00437.20 CEH12502.1 - 2e-11 43.5 0.1 0.051 12.6 0.0 6.9 7 0 0 7 7 6 1 Type II/IV secretion system protein RNA_helicase PF00910.22 CEH12502.1 - 7.1e-10 39.2 0.1 6 7.3 0.0 6.5 6 0 0 6 6 6 0 RNA helicase AAA_14 PF13173.6 CEH12502.1 - 1.2e-09 38.3 0.0 0.0093 16.0 0.0 6.2 7 0 0 7 7 5 1 AAA domain AAA_19 PF13245.6 CEH12502.1 - 1.5e-09 38.3 3.8 1.6 9.1 0.0 6.6 6 0 0 6 6 5 2 AAA domain Sigma54_activ_2 PF14532.6 CEH12502.1 - 3.1e-09 37.1 0.9 0.01 15.9 0.0 5.1 5 0 0 5 5 4 2 Sigma-54 interaction domain AAA_25 PF13481.6 CEH12502.1 - 4.8e-09 36.1 6.5 1.9 8.0 0.0 6.4 6 0 0 6 6 5 3 AAA domain AAA_23 PF13476.6 CEH12502.1 - 7.9e-09 36.3 5.6 1.4 9.4 0.0 7.5 8 0 0 8 8 7 2 AAA domain Rad17 PF03215.15 CEH12502.1 - 9.6e-09 35.4 0.4 0.25 11.2 0.0 6.2 6 0 0 6 6 6 1 Rad17 P-loop domain RuvB_N PF05496.12 CEH12502.1 - 2.6e-08 33.7 3.5 0.19 11.4 0.0 6.7 7 0 0 7 7 6 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CEH12502.1 - 3.7e-08 33.3 0.8 2.6 7.8 0.0 5.9 5 0 0 5 5 5 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CEH12502.1 - 4.9e-08 33.1 0.0 3.7 7.4 0.0 5.7 6 0 0 6 6 5 0 RsgA GTPase Mg_chelatase PF01078.21 CEH12502.1 - 5.8e-08 32.4 3.9 3.2 7.1 0.0 8.1 8 0 0 8 8 8 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 CEH12502.1 - 1.8e-07 30.8 0.0 2.8 7.8 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain TniB PF05621.11 CEH12502.1 - 1.9e-07 30.6 0.0 0.41 10.0 0.0 5.1 5 0 0 5 5 4 1 Bacterial TniB protein NACHT PF05729.12 CEH12502.1 - 5.6e-07 29.6 9.0 0.95 9.4 0.1 7.1 8 0 0 8 8 6 1 NACHT domain SRP54 PF00448.22 CEH12502.1 - 9.3e-06 25.4 3.1 1.1 8.8 0.1 4.7 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain Roc PF08477.13 CEH12502.1 - 1.8e-05 24.9 0.3 12 6.2 0.1 5.5 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CEH12502.1 - 2e-05 24.3 1.7 4 7.0 0.0 5.8 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 CEH12502.1 - 4.1e-05 22.9 0.5 3.4 6.8 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 CEH12502.1 - 0.0002 21.3 1.0 18 5.2 0.1 5.6 6 0 0 6 6 6 0 NTPase PduV-EutP PF10662.9 CEH12502.1 - 0.00025 20.8 1.1 6 6.6 0.0 4.6 5 0 0 5 5 4 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.13 CEH12502.1 - 0.0005 19.4 1.3 0.24 10.6 0.1 4.1 4 0 0 4 4 4 1 TIP49 P-loop domain MMR_HSR1 PF01926.23 CEH12502.1 - 0.00089 19.3 0.0 18 5.5 0.0 5.5 5 0 0 5 5 5 0 50S ribosome-binding GTPase AAA_8 PF12780.7 CEH12502.1 - 0.002 17.5 0.9 5.8 6.2 0.0 4.4 5 0 0 5 5 4 0 P-loop containing dynein motor region D4 AAA_24 PF13479.6 CEH12502.1 - 0.0024 17.6 0.0 28 4.4 0.0 5.1 6 0 0 6 6 5 0 AAA domain DEAD PF00270.29 CEH12502.1 - 0.0036 17.1 0.2 10 5.8 0.0 4.2 4 0 0 4 4 3 0 DEAD/DEAH box helicase SRPRB PF09439.10 CEH12502.1 - 0.0057 16.1 0.1 31 3.9 0.0 5.1 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit ResIII PF04851.15 CEH12502.1 - 0.012 15.6 0.1 23 4.9 0.0 3.8 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit IPT PF01745.16 CEH12502.1 - 0.043 13.2 0.0 17 4.7 0.0 3.4 3 0 0 3 3 3 0 Isopentenyl transferase CbiA PF01656.23 CEH12502.1 - 0.067 13.3 4.2 7.3 6.7 0.1 4.4 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.18 CEH12502.1 - 0.096 12.4 0.0 5.6 6.6 0.0 3.1 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CEH12502.1 - 0.2 11.6 0.0 8.6 6.2 0.0 3.2 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_21 PF13304.6 CEH12502.1 - 0.31 10.8 2.5 26 4.5 0.0 4.4 5 0 0 5 5 4 0 AAA domain, putative AbiEii toxin, Type IV TA system CPT PF07931.12 CEH12502.1 - 0.33 10.8 5.0 26 4.6 0.0 6.1 8 1 0 8 8 6 0 Chloramphenicol phosphotransferase-like protein dNK PF01712.19 CEH12502.1 - 0.38 10.6 2.0 77 3.0 0.0 4.5 5 0 0 5 5 5 0 Deoxynucleoside kinase PhoH PF02562.16 CEH12502.1 - 1 8.8 3.8 22 4.4 0.0 3.6 4 0 0 4 4 4 0 PhoH-like protein TPR_1 PF00515.28 CEH12503.1 - 5.8e-07 29.1 2.9 0.0017 18.1 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.31 CEH12503.1 - 1.2e-05 25.4 0.0 2.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 CEH12503.1 - 0.00021 21.2 12.4 0.0013 18.7 1.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.31 CEH12503.1 - 0.00029 20.6 0.0 0.0011 18.9 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Apo-CII PF05355.11 CEH12503.1 - 0.84 9.8 4.0 0.44 10.7 0.4 2.4 2 0 0 2 2 2 0 Apolipoprotein C-II CPSF_A PF03178.15 CEH12504.1 - 1e-70 238.6 0.0 1.8e-70 237.9 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region NifW PF03206.14 CEH12504.1 - 0.2 12.2 0.4 0.74 10.4 0.0 2.2 3 0 0 3 3 3 0 Nitrogen fixation protein NifW Med13_N PF11597.8 CEH12505.1 - 1.4e-05 24.7 10.5 0.0002 20.8 0.0 2.9 3 0 0 3 3 3 2 Mediator complex subunit 13 N-terminal DUF1629 PF07791.11 CEH12505.1 - 0.16 12.1 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) Serglycin PF04360.12 CEH12505.1 - 0.44 10.5 7.4 0.38 10.7 0.5 3.0 2 0 0 2 2 2 0 Serglycin PA26 PF04636.13 CEH12505.1 - 1.3 7.8 5.2 39 3.0 7.4 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Abhydrolase_6 PF12697.7 CEH12506.1 - 3.7e-13 50.6 0.3 4.6e-13 50.3 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEH12506.1 - 6.4e-13 48.9 0.2 1.3e-11 44.6 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH12506.1 - 6.4e-11 42.0 0.2 1.2e-10 41.0 0.2 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Fungal_trans PF04082.18 CEH12507.1 - 0.0072 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 CEH12508.1 - 1.1e-27 96.8 0.1 2.1e-27 95.8 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH12508.1 - 2.6e-12 47.0 1.0 1.9e-11 44.2 1.0 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 CEH12508.1 - 4.1e-12 46.2 0.4 9.3e-12 45.0 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2306 PF10067.9 CEH12508.1 - 0.00044 20.5 3.6 0.011 16.0 3.6 2.6 1 1 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF5118 PF17162.4 CEH12508.1 - 0.0023 17.7 0.0 0.0094 15.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5118) Epimerase PF01370.21 CEH12508.1 - 0.014 14.9 0.4 0.03 13.8 0.4 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CEH12508.1 - 0.023 14.6 0.2 0.043 13.7 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CEH12508.1 - 0.098 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2OG-FeII_Oxy_3 PF13640.6 CEH12509.1 - 0.0034 18.2 1.1 0.027 15.4 0.4 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 CEH12509.1 - 0.02 14.7 0.2 0.44 10.3 0.1 2.0 1 1 1 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 CEH12510.1 - 2.5e-24 85.9 47.6 2.5e-24 85.9 47.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Anophelin PF10731.9 CEH12510.1 - 0.17 11.7 2.0 0.44 10.4 0.8 2.2 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Trp_DMAT PF11991.8 CEH12511.1 - 8e-61 206.5 0.0 1.1e-60 206.0 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 CEH12512.1 - 1.8e-58 198.4 0.0 7.5e-58 196.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF485 PF04341.12 CEH12512.1 - 0.17 11.9 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 CLZ PF16526.5 CEH12513.1 - 0.1 13.0 3.2 8.6 6.8 0.1 3.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Zn_clus PF00172.18 CEH12513.1 - 1.9 8.7 11.6 1.7 8.8 3.6 1.9 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_5_C PF18564.1 CEH12514.1 - 9.2e-11 42.1 0.0 3.8e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 CEH12514.1 - 1.4e-07 31.2 0.0 1.9e-06 27.6 0.1 2.3 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF2183 PF09949.9 CEH12517.1 - 2.5e-24 85.5 0.0 6e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 CEH12517.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DSHCT PF08148.12 CEH12518.1 - 6.5e-54 182.0 1.2 1.5e-53 180.8 0.8 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 CEH12518.1 - 2.2e-29 103.3 0.0 3.3e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 CEH12518.1 - 3.1e-19 69.4 0.0 7.4e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CEH12518.1 - 5.2e-07 29.8 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEH12518.1 - 1.9e-05 25.0 0.0 7.1e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CEH12518.1 - 0.065 13.5 0.0 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 CEH12521.1 - 7.4e-26 90.9 55.0 1.1e-22 80.5 37.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1634 PF07843.11 CEH12521.1 - 0.0054 16.8 2.8 0.0054 16.8 2.8 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1634) DNA_pol_E_B PF04042.16 CEH12524.1 - 3.7e-34 117.9 0.0 5.4e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CEH12524.1 - 3.3e-23 82.2 0.0 5.1e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain LodA_N PF17990.1 CEH12524.1 - 0.049 13.6 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal RhoGEF PF00621.20 CEH12525.1 - 7.5e-17 62.2 0.0 1.4e-12 48.2 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain Bromodomain PF00439.25 CEH12526.1 - 2.4e-51 171.8 0.0 1.1e-17 63.8 0.0 3.7 3 0 0 3 3 3 3 Bromodomain HEAT_2 PF13646.6 CEH12526.1 - 0.0016 18.8 5.8 0.011 16.1 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats Peptidase_M1 PF01433.20 CEH12526.1 - 0.0061 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3881 PF12997.7 CEH12526.1 - 0.098 11.9 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) CENP-H PF05837.12 CEH12527.1 - 2.5e-11 43.9 1.1 2.5e-11 43.9 1.1 1.7 2 0 0 2 2 2 1 Centromere protein H (CENP-H) HTH_1 PF00126.27 CEH12527.1 - 0.075 13.0 1.6 1.1 9.2 0.2 2.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family RXLR PF16810.5 CEH12527.1 - 4.4 7.7 7.0 1.4 9.4 1.2 2.4 1 1 1 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Nbl1_Borealin_N PF10444.9 CEH12528.1 - 1.1e-08 34.6 0.0 1.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal SLY PF12485.8 CEH12528.1 - 0.012 16.3 2.0 0.016 16.0 2.0 1.1 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Wzy_C PF04932.15 CEH12531.1 - 0.32 10.6 3.2 0.36 10.4 3.2 1.3 1 0 0 1 1 1 0 O-Antigen ligase Beach PF02138.18 CEH12533.1 - 1.7e-109 365.5 0.0 2.5e-109 364.9 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CEH12533.1 - 6e-09 35.9 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH FYVE PF01363.21 CEH12533.1 - 2e-05 24.6 4.1 4.6e-05 23.5 4.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger Laminin_G_3 PF13385.6 CEH12533.1 - 0.0002 21.6 0.0 0.00062 19.9 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF3689 PF12463.8 CEH12533.1 - 0.00033 20.1 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) zf-AN1 PF01428.16 CEH12533.1 - 1.5 9.1 4.7 3.4 7.9 4.7 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger FYVE_2 PF02318.16 CEH12533.1 - 5.7 7.2 6.1 15 5.8 6.1 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger CMAS PF02353.20 CEH12534.1 - 5.2e-30 104.7 0.0 1.2e-18 67.3 0.0 2.9 2 1 1 3 3 3 2 Mycolic acid cyclopropane synthetase ADH_N PF08240.12 CEH12535.1 - 8.7e-13 48.1 0.0 1.1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEH12536.1 - 2.8e-13 50.0 0.8 1.2e-12 48.0 0.8 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Gp_dh_N PF00044.24 CEH12536.1 - 0.072 13.4 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 CEH12536.1 - 0.1 13.7 0.1 0.28 12.2 0.0 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CEH12536.1 - 0.13 11.7 0.0 0.46 9.9 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Pkinase PF00069.25 CEH12537.1 - 6.5e-67 225.7 0.0 8.4e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH12537.1 - 1.1e-28 100.3 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEH12537.1 - 0.02 14.8 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEH12537.1 - 0.027 13.4 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Aldo_ket_red PF00248.21 CEH12538.1 - 2.6e-27 95.8 0.0 1.4e-26 93.4 0.0 2.0 2 0 0 2 2 2 1 Aldo/keto reductase family Yae1_N PF09811.9 CEH12538.1 - 2.9e-09 36.5 0.5 5.9e-09 35.5 0.5 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF5320 PF17253.2 CEH12538.1 - 4.8 8.3 7.8 1.3e+02 3.7 4.2 3.5 2 1 0 2 2 2 0 Family of unknown function (DUF5320) zf_CCCH_4 PF18345.1 CEH12541.1 - 1.5e-13 50.3 32.6 3.2e-06 27.0 3.1 5.4 5 0 0 5 5 5 4 Zinc finger domain zf-CCCH PF00642.24 CEH12541.1 - 1.2e-12 47.3 30.3 9.6e-05 22.2 1.2 5.4 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CEH12541.1 - 3.6e-10 40.5 20.8 0.00028 21.6 0.5 5.2 1 1 4 5 5 5 4 Torus domain zf-CCHC PF00098.23 CEH12541.1 - 4.4e-06 26.5 0.9 4.4e-06 26.5 0.9 2.6 3 0 0 3 3 3 1 Zinc knuckle zf-CCCH_4 PF18044.1 CEH12541.1 - 1.7e-05 24.5 0.6 1.7e-05 24.5 0.6 4.8 5 1 0 5 5 5 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CEH12541.1 - 2 8.6 17.1 29 4.9 8.2 4.3 1 1 3 4 4 4 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CEH12541.1 - 4 8.0 39.4 0.73 10.4 2.0 6.0 6 0 0 6 6 6 0 RNA-binding, Nab2-type zinc finger NIF PF03031.18 CEH12542.1 - 3.8e-21 75.5 0.0 4.4e-20 72.0 0.0 2.3 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 CEH12542.1 - 1.7e-08 34.3 0.0 4.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CEH12542.1 - 0.0014 19.0 0.0 0.0034 17.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CEH12542.1 - 0.0068 16.8 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain MFS_1 PF07690.16 CEH12543.1 - 1e-36 126.6 21.8 1e-36 126.6 21.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily F-actin_cap_A PF01267.17 CEH12544.1 - 2.1e-72 243.7 0.0 2.5e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF924 PF06041.11 CEH12544.1 - 0.053 13.6 0.2 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF924) SafA PF17073.5 CEH12545.1 - 2.6 8.1 3.8 12 5.9 0.8 2.9 3 0 0 3 3 3 0 Two-component-system connector protein AAA PF00004.29 CEH12546.1 - 5e-22 78.8 0.1 1.4e-10 41.7 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEH12546.1 - 3e-12 47.3 3.5 7e-05 23.3 0.1 3.9 3 1 1 4 4 4 2 AAA ATPase domain AAA_lid_3 PF17862.1 CEH12546.1 - 1.7e-07 30.9 0.2 5.2e-07 29.4 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 CEH12546.1 - 2.7e-07 31.2 0.1 0.021 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEH12546.1 - 5.6e-07 29.9 1.8 0.0033 17.7 0.0 3.2 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 CEH12546.1 - 1.9e-06 28.2 0.0 0.012 16.0 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 CEH12546.1 - 4.1e-06 27.0 1.9 0.041 14.0 0.1 3.1 3 1 0 3 3 2 2 AAA domain TsaE PF02367.17 CEH12546.1 - 3.3e-05 23.9 0.2 0.23 11.5 0.1 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CEH12546.1 - 3.5e-05 23.6 0.1 0.026 14.2 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_25 PF13481.6 CEH12546.1 - 3.7e-05 23.4 1.8 0.22 11.1 0.5 2.9 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CEH12546.1 - 4.3e-05 23.4 0.1 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 CEH12546.1 - 9.2e-05 23.0 0.2 0.029 14.9 0.0 3.0 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.6 CEH12546.1 - 9.6e-05 22.8 0.2 0.16 12.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CEH12546.1 - 0.00022 20.5 0.0 0.015 14.5 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 CEH12546.1 - 0.00027 20.9 0.8 0.97 9.3 0.0 3.0 2 1 1 3 3 3 2 NACHT domain APS_kinase PF01583.20 CEH12546.1 - 0.00034 20.5 0.0 0.31 10.9 0.0 3.4 2 1 1 3 3 3 1 Adenylylsulphate kinase IstB_IS21 PF01695.17 CEH12546.1 - 0.00037 20.3 0.1 0.54 10.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 CEH12546.1 - 0.00037 20.5 0.3 0.41 10.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CEH12546.1 - 0.00052 19.6 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 CEH12546.1 - 0.00061 19.8 0.0 0.032 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CEH12546.1 - 0.001 18.8 0.1 0.055 13.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CEH12546.1 - 0.0012 18.2 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin NTPase_1 PF03266.15 CEH12546.1 - 0.0014 18.5 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 NTPase ATPase PF06745.13 CEH12546.1 - 0.0022 17.4 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 2 KaiC AAA_24 PF13479.6 CEH12546.1 - 0.0023 17.7 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CEH12546.1 - 0.0027 17.5 0.0 0.025 14.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain CbiA PF01656.23 CEH12546.1 - 0.0029 17.6 0.0 0.012 15.6 0.0 1.8 2 1 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 CEH12546.1 - 0.0046 16.7 0.7 0.14 11.9 0.1 2.7 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 CEH12546.1 - 0.006 16.5 0.5 2.5 8.0 0.1 3.1 4 0 0 4 4 3 1 Rad17 P-loop domain CLP1_P PF16575.5 CEH12546.1 - 0.01 15.6 0.0 0.18 11.6 0.0 2.6 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_28 PF13521.6 CEH12546.1 - 0.013 15.8 4.7 1.1 9.5 1.0 3.2 2 1 1 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 CEH12546.1 - 0.015 15.4 0.0 0.41 10.7 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 CEH12546.1 - 0.016 14.6 0.6 0.24 10.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CEH12546.1 - 0.017 14.3 0.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 CEH12546.1 - 0.02 15.0 0.1 1.2 9.2 0.0 3.0 3 1 0 3 3 3 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CEH12546.1 - 0.02 14.7 0.0 0.09 12.6 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 CEH12546.1 - 0.024 15.0 0.2 2 8.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain IPT PF01745.16 CEH12546.1 - 0.049 13.0 0.1 9.4 5.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase cobW PF02492.19 CEH12546.1 - 0.062 12.9 0.0 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 CEH12546.1 - 0.083 12.1 0.1 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 CEH12546.1 - 0.088 12.0 0.2 0.62 9.2 0.0 2.3 2 1 1 3 3 3 0 TIP49 P-loop domain Cytidylate_kin PF02224.18 CEH12546.1 - 0.096 12.4 0.1 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_3 PF07726.11 CEH12546.1 - 0.098 12.5 0.0 0.89 9.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pyridoxal_deC PF00282.19 CEH12546.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain PRK PF00485.18 CEH12546.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 CEH12546.1 - 0.17 11.1 0.0 0.51 9.6 0.0 1.7 2 0 0 2 2 2 0 Septin Glyco_hydro_42 PF02449.15 CEH12547.1 - 2.7e-77 260.7 3.2 3.8e-77 260.1 3.2 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.10 CEH12547.1 - 6.1e-25 87.9 0.0 1.1e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain DUF4434 PF14488.6 CEH12547.1 - 0.076 13.0 0.2 0.48 10.4 0.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) TPR_MLP1_2 PF07926.12 CEH12550.1 - 0.00028 20.9 17.6 0.00028 20.9 17.6 23.7 2 1 21 24 24 24 10 TPR/MLP1/MLP2-like protein SOGA PF11365.8 CEH12550.1 - 0.0058 17.7 7.9 0.0058 17.7 7.9 22.5 4 4 21 27 27 27 1 Protein SOGA Uso1_p115_C PF04871.13 CEH12550.1 - 0.0073 16.7 26.7 0.0073 16.7 26.7 25.6 5 1 19 26 26 26 2 Uso1 / p115 like vesicle tethering protein, C terminal region BCDHK_Adom3 PF10436.9 CEH12551.1 - 7.6e-21 74.6 0.1 1e-20 74.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CEH12551.1 - 3.7e-08 33.9 0.0 2.5e-06 28.0 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEH12551.1 - 2.9e-07 30.4 0.0 5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAR1 PF03101.15 CEH12552.1 - 3.2e-06 27.7 1.1 1.2e-05 25.9 1.1 2.0 1 0 0 1 1 1 1 FAR1 DNA-binding domain JAKMIP_CC3 PF16034.5 CEH12553.1 - 0.0081 16.1 1.3 0.01 15.8 1.3 1.1 1 0 0 1 1 1 1 JAKMIP CC3 domain LapA_dom PF06305.11 CEH12553.1 - 0.031 14.1 0.9 0.09 12.6 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain GT87 PF09594.10 CEH12553.1 - 0.052 13.2 0.2 0.06 13.0 0.2 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 87 GRIM-19 PF06212.12 CEH12553.1 - 0.064 13.2 0.1 0.088 12.8 0.1 1.3 1 0 0 1 1 1 0 GRIM-19 protein PgaD PF13994.6 CEH12553.1 - 0.078 13.0 0.6 0.11 12.6 0.5 1.4 1 1 0 1 1 1 0 PgaD-like protein Shugoshin_N PF07558.11 CEH12553.1 - 0.16 11.9 2.5 0.25 11.2 2.5 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region ZapB PF06005.12 CEH12553.1 - 0.21 12.0 3.3 0.15 12.5 1.2 1.7 1 1 1 2 2 2 0 Cell division protein ZapB DUF4381 PF14316.6 CEH12553.1 - 0.45 10.7 2.1 0.57 10.4 1.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) DivIC PF04977.15 CEH12553.1 - 0.46 10.3 5.5 7.8 6.4 0.3 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF4381 PF14316.6 CEH12554.1 - 0.0096 16.2 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) VirB8 PF04335.13 CEH12554.1 - 0.052 13.4 0.0 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 VirB8 protein PA28_beta PF02252.18 CEH12556.1 - 0.0005 19.8 0.1 0.00068 19.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit DUF1456 PF07308.13 CEH12556.1 - 0.07 13.5 0.3 0.24 11.7 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1456) DUF4200 PF13863.6 CEH12556.1 - 0.2 12.1 10.5 0.33 11.3 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF5401 PF17380.2 CEH12556.1 - 1.8 6.5 9.3 2.1 6.3 9.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) ADSL_C PF10397.9 CEH12557.1 - 2.5e-16 60.0 0.0 9.6e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Lyase_1 PF00206.20 CEH12557.1 - 5.9e-08 32.5 0.0 1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Lyase DUF4179 PF13786.6 CEH12558.1 - 0.086 13.3 0.0 6.1 7.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DUF1043 PF06295.12 CEH12558.1 - 1 9.4 4.8 1.7 8.6 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1043) PEP-utilisers_N PF05524.13 CEH12558.1 - 2.1 8.5 6.0 18 5.6 0.5 3.7 4 0 0 4 4 4 0 PEP-utilising enzyme, N-terminal HemX PF04375.14 CEH12558.1 - 6.8 5.9 10.5 5.7 6.1 0.4 3.9 5 0 0 5 5 5 0 HemX, putative uroporphyrinogen-III C-methyltransferase Y_phosphatase2 PF03162.13 CEH12559.1 - 4e-51 172.9 0.0 4.8e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CEH12559.1 - 0.0019 18.2 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEH12559.1 - 0.029 13.9 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 CEH12559.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain ATF7IP_BD PF16788.5 CEH12560.1 - 0.049 13.7 6.0 0.073 13.2 6.0 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain CDC45 PF02724.14 CEH12560.1 - 0.37 9.0 2.3 0.41 8.9 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MPC PF03650.13 CEH12561.1 - 6.1e-36 122.9 0.1 7.4e-36 122.6 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DNA_primase_S PF01896.19 CEH12563.1 - 4.3e-51 173.5 0.0 9.9e-51 172.3 0.0 1.6 1 1 0 1 1 1 1 DNA primase small subunit DS PF01916.17 CEH12564.1 - 3.6e-132 440.0 0.0 4.2e-132 439.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase PCSK9_C3 PF18463.1 CEH12565.1 - 0.00074 19.7 0.3 1.4 9.2 0.1 2.6 2 0 0 2 2 2 2 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Use1 PF09753.9 CEH12567.1 - 0.24 11.1 4.7 0.12 12.1 2.2 1.7 1 1 1 2 2 2 0 Membrane fusion protein Use1 MFS_1 PF07690.16 CEH12570.1 - 6.6e-22 77.9 41.5 3.5e-13 49.2 28.4 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.16 CEH12570.1 - 0.05 13.3 3.3 5.1 6.8 0.1 2.9 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CEH12572.1 - 2e-22 79.6 24.2 2e-22 79.6 24.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 CEH12572.1 - 1.2 8.9 5.7 3.6 7.4 0.8 2.7 2 0 0 2 2 2 0 Bacteriophage holin family HP1 YrhK PF14145.6 CEH12572.1 - 3 7.8 9.3 0.63 10.0 1.8 3.2 3 1 0 3 3 3 0 YrhK-like protein Hva1_TUDOR PF11160.8 CEH12575.1 - 3.8e-15 55.8 2.3 3.8e-15 55.8 2.3 3.0 2 1 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain SHE3 PF17078.5 CEH12576.1 - 0.0014 18.4 5.8 0.0014 18.4 5.8 2.7 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 LOH1CR12 PF10158.9 CEH12576.1 - 0.29 11.2 3.7 3.8 7.6 0.0 3.3 1 1 2 3 3 3 0 Tumour suppressor protein Baculo_PEP_C PF04513.12 CEH12576.1 - 0.66 10.0 5.0 11 6.1 2.7 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 CEH12576.1 - 0.68 10.2 3.6 1.9 8.7 0.1 3.2 3 0 0 3 3 3 0 Haemolysin XhlA LPP PF04728.13 CEH12576.1 - 0.82 10.1 7.1 13 6.3 2.8 3.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF948 PF06103.11 CEH12576.1 - 1.6 9.0 9.3 3.7 7.9 0.7 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3619 PF12279.8 CEH12576.1 - 5.1 7.4 9.3 0.66 10.3 3.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Abhydrolase_6 PF12697.7 CEH12578.1 - 5.3e-05 23.9 1.9 5.3e-05 23.9 1.9 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CEH12578.1 - 0.011 15.5 0.1 0.023 14.4 0.1 1.5 1 1 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 CEH12578.1 - 0.022 14.1 0.0 0.058 12.6 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 CEH12578.1 - 0.029 14.1 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family ARL17 PF15840.5 CEH12578.1 - 0.052 13.9 0.8 0.19 12.1 0.8 1.9 1 0 0 1 1 1 0 ADP-ribosylation factor-like protein 17 Abhydrolase_3 PF07859.13 CEH12578.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 CEH12578.1 - 0.084 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme HIT PF01230.23 CEH12579.1 - 0.013 16.3 0.1 0.016 15.9 0.1 1.3 1 1 0 1 1 1 0 HIT domain SLD5_C PF16922.5 CEH12582.1 - 1.2e-13 51.0 0.0 2.6e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CEH12582.1 - 1.8e-05 25.2 0.0 2.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein MFS_1 PF07690.16 CEH12583.1 - 1.2e-35 123.1 30.1 1.2e-35 123.1 30.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH12583.1 - 1.9e-10 40.2 14.4 5.6e-10 38.7 5.7 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 CEH12583.1 - 2.7e-10 39.3 5.9 2.7e-10 39.3 5.9 2.1 1 1 2 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 CEH12583.1 - 4.1e-08 32.9 0.6 4.1e-08 32.9 0.6 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB FPN1 PF06963.12 CEH12583.1 - 0.0014 17.3 0.5 0.0025 16.4 0.5 1.4 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF4551 PF15087.6 CEH12583.1 - 9.4 4.9 5.2 13 4.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Zn-C2H2_12 PF18112.1 CEH12584.1 - 0.095 13.2 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain DUF2423 PF10338.9 CEH12585.1 - 8.1e-10 38.8 4.6 8.1e-10 38.8 4.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) PAC4 PF16093.5 CEH12585.1 - 0.25 11.5 2.9 2.7 8.2 1.4 2.5 2 1 0 2 2 2 0 Proteasome assembly chaperone 4 Paf1 PF03985.13 CEH12585.1 - 1.1 8.2 7.0 1.3 7.9 7.0 1.0 1 0 0 1 1 1 0 Paf1 DUF4451 PF14616.6 CEH12586.1 - 5.9e-13 49.1 0.1 1e-12 48.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Response_reg PF00072.24 CEH12587.1 - 9.6e-21 74.1 0.0 1.4e-15 57.4 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain Lactamase_B_2 PF12706.7 CEH12588.1 - 1.7e-09 37.5 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NifU_N PF01592.16 CEH12589.1 - 2.6e-51 173.1 0.0 4.1e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain Sugar_tr PF00083.24 CEH12590.1 - 1e-21 77.4 19.5 8.2e-21 74.4 19.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Lactamase_B_2 PF12706.7 CEH12591.1 - 4.2e-11 42.7 2.3 2.9e-07 30.2 0.3 2.7 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 CEH12591.1 - 8.8e-07 28.5 0.0 3e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease PALP PF00291.25 CEH12592.1 - 1e-57 195.8 0.1 1.6e-56 191.9 0.1 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF755 PF05501.11 CEH12592.1 - 0.11 12.8 3.6 0.52 10.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) LSM PF01423.22 CEH12593.1 - 9.7e-14 50.8 0.0 1.3e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEH12593.1 - 0.0049 17.0 0.2 0.012 15.8 0.2 1.6 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 CEH12593.1 - 0.087 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain FUSC_2 PF13515.6 CEH12594.1 - 2.1e-15 57.0 14.0 2.1e-15 57.0 14.0 2.8 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 CEH12594.1 - 2.1e-13 49.7 10.9 2.1e-13 49.7 10.9 3.4 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.8 CEH12594.1 - 7.3e-09 35.0 9.0 5.1e-07 28.9 2.6 3.2 3 0 0 3 3 3 2 Aluminium activated malate transporter ArAE_2_N PF10337.9 CEH12594.1 - 7.2e-07 28.6 5.6 0.00015 21.0 0.0 3.4 3 0 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 CEH12594.1 - 2.9e-06 27.3 1.4 7.7e-06 25.9 1.1 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_1 PF06081.11 CEH12594.1 - 0.00012 22.3 3.0 0.00012 22.3 3.0 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 1 PDT PF00800.18 CEH12594.1 - 0.083 12.7 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 Prephenate dehydratase YqhR PF11085.8 CEH12594.1 - 0.15 12.0 0.9 0.3 11.0 0.9 1.4 1 0 0 1 1 1 0 Conserved membrane protein YqhR Asparaginase PF00710.20 CEH12595.1 - 7.3e-44 149.6 0.3 1.1e-43 149.0 0.3 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CEH12595.1 - 4.4e-15 55.9 0.0 9.6e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain AA_permease PF00324.21 CEH12596.1 - 5.2e-112 374.9 32.5 6.2e-112 374.6 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEH12596.1 - 8.1e-32 110.6 35.2 1.2e-31 110.0 35.2 1.3 1 1 0 1 1 1 1 Amino acid permease Pro-kuma_activ PF09286.11 CEH12597.1 - 1.2e-42 145.6 1.2 1.4e-42 145.4 0.4 1.5 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CEH12597.1 - 1.3e-05 24.7 1.3 2.1e-05 23.9 1.3 1.3 1 0 0 1 1 1 1 Subtilase family DUF1770 PF08589.10 CEH12598.1 - 5.8e-06 27.2 0.9 9.7e-06 26.5 0.2 1.6 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) Thia_YuaJ PF09515.10 CEH12598.1 - 0.18 11.8 0.2 0.25 11.4 0.2 1.1 1 0 0 1 1 1 0 Thiamine transporter protein (Thia_YuaJ) DUF3835 PF12927.7 CEH12599.1 - 0.00089 20.1 6.0 0.16 12.9 0.1 4.3 3 1 0 3 3 3 2 Domain of unknown function (DUF3835) Rpn3_C PF08375.11 CEH12599.1 - 1.1 9.7 3.3 2 8.9 0.7 2.9 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal HalX PF08663.10 CEH12599.1 - 2.3 8.6 13.6 0.35 11.2 1.6 3.9 3 0 0 3 3 3 0 HalX domain Methyltransf_4 PF02390.17 CEH12600.1 - 7.9e-48 162.2 0.0 2.4e-36 124.8 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_25 PF13649.6 CEH12600.1 - 0.00023 21.8 0.0 0.007 17.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH12600.1 - 0.0027 17.5 0.0 0.034 13.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH12600.1 - 0.0045 17.7 0.0 0.019 15.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH12600.1 - 0.0054 17.4 0.0 1 10.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 CEH12600.1 - 0.019 14.5 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Histone methylation protein DOT1 MTS PF05175.14 CEH12600.1 - 0.048 13.2 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain RNA_pol_Rpb4 PF03874.16 CEH12601.1 - 1.6e-10 41.4 1.2 6.3e-10 39.5 1.2 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 MRP-L47 PF06984.13 CEH12602.1 - 3.1e-15 56.0 1.3 5.1e-15 55.4 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 CEH12602.1 - 0.011 15.7 0.4 0.011 15.7 0.4 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein Macoilin PF09726.9 CEH12604.1 - 0.0025 16.5 22.2 0.0031 16.2 22.2 1.1 1 0 0 1 1 1 1 Macoilin family R2K_2 PF18299.1 CEH12604.1 - 0.011 15.6 0.7 0.021 14.7 0.7 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 AAA_13 PF13166.6 CEH12604.1 - 0.1 11.3 25.2 0.063 11.9 23.3 1.4 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.11 CEH12604.1 - 0.21 10.4 39.7 0.56 9.0 19.3 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein HAP1_N PF04849.13 CEH12604.1 - 0.69 9.1 36.0 2.2 7.4 35.2 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 CEH12604.1 - 1.1 9.3 18.7 1.1 9.4 4.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 CEH12604.1 - 1.8 8.3 16.4 0.17 11.7 3.2 3.5 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) BLOC1_2 PF10046.9 CEH12604.1 - 3.4 8.0 21.0 0.054 13.8 3.8 3.8 2 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 CEH12604.1 - 5 7.2 39.0 2.5 8.2 6.8 3.9 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 CEH12604.1 - 7.1 6.2 38.9 1.3 8.7 30.3 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 CEH12604.1 - 7.5 7.0 18.2 14 6.2 1.2 4.3 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Retrotrans_gag PF03732.17 CEH12605.1 - 1.8e-05 24.9 0.0 4.5e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 CEH12606.1 - 5.4e-18 65.3 0.0 7.6e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CEH12607.1 - 8.3e-33 112.8 0.3 1.4e-32 112.1 0.3 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEH12607.1 - 1.8e-27 95.3 0.1 3.1e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEH12607.1 - 7.8e-19 67.5 0.2 1.9e-18 66.3 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEH12607.1 - 1.9e-13 50.7 0.0 1.6e-12 47.7 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 CEH12607.1 - 1.7e-05 24.6 0.0 5e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEH12607.1 - 8.2e-05 22.7 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DnaJ-X PF14308.6 CEH12611.1 - 1.4e-50 171.6 6.8 1.4e-50 171.6 6.8 2.1 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CEH12611.1 - 2.1e-26 91.8 0.3 9.1e-26 89.8 0.3 2.2 1 0 0 1 1 1 1 DnaJ domain Tmemb_55A PF09788.9 CEH12611.1 - 0.093 11.8 0.9 0.18 10.8 0.9 1.4 1 0 0 1 1 1 0 Transmembrane protein 55A Ubiq_cyt_C_chap PF03981.12 CEH12611.1 - 0.16 12.0 2.9 4.5 7.4 0.0 2.5 2 1 0 2 2 2 0 Ubiquinol-cytochrome C chaperone IBR PF01485.21 CEH12611.1 - 0.22 11.8 1.7 0.5 10.6 1.7 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ASFV_J13L PF05568.11 CEH12611.1 - 0.98 9.1 2.9 3.5 7.3 0.4 2.7 3 0 0 3 3 3 0 African swine fever virus J13L protein RNA_pol_Rpc4 PF05132.14 CEH12611.1 - 2 8.8 5.0 0.57 10.6 1.7 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 CDT1_C PF16679.5 CEH12611.1 - 2.3 8.7 8.0 0.76 10.2 4.2 2.2 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain HA2 PF04408.23 CEH12611.1 - 7.8 6.8 6.3 6.9 7.0 0.2 2.5 2 0 0 2 2 2 0 Helicase associated domain (HA2) DUF4187 PF13821.6 CEH12612.1 - 5.2e-18 64.6 1.9 5.2e-18 64.6 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 CEH12612.1 - 5e-05 23.1 0.8 0.00014 21.7 0.8 1.8 1 0 0 1 1 1 1 G-patch domain Ribosomal_60s PF00428.19 CEH12612.1 - 9.6 6.9 11.5 2.5 8.8 5.2 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein SAM_PNT PF02198.16 CEH12613.1 - 0.04 13.9 0.0 0.067 13.2 0.0 1.4 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF3439 PF11921.8 CEH12617.1 - 0.84 9.6 8.2 8.6 6.4 4.5 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) NAD_binding_7 PF13241.6 CEH12619.1 - 1.3e-27 96.3 0.0 2.1e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CEH12619.1 - 1e-24 85.9 0.1 1.6e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 CEH12619.1 - 6e-12 44.8 1.2 6e-12 44.8 1.2 2.1 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central SH2_2 PF14633.6 CEH12620.1 - 1.4e-68 230.6 0.0 1.4e-68 230.6 0.0 2.3 2 0 0 2 2 2 1 SH2 domain SPT6_acidic PF14632.6 CEH12620.1 - 3e-20 72.6 35.6 3e-20 72.6 35.6 7.0 5 2 2 7 7 7 2 Acidic N-terminal SPT6 YqgF PF14639.6 CEH12620.1 - 8.3e-20 71.1 0.0 1.8e-18 66.7 0.0 2.5 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 CEH12620.1 - 1.5e-15 57.4 0.0 3.5e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 CEH12620.1 - 1e-09 38.8 0.0 3.1e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_9 PF17674.1 CEH12620.1 - 0.00016 22.5 0.0 0.0017 19.2 0.1 2.9 2 0 0 2 2 2 1 HHH domain ProQ_C PF17516.2 CEH12620.1 - 0.0047 16.3 0.8 2 7.9 0.1 2.4 2 0 0 2 2 2 2 ProQ C-terminal domain ALS_ss_C PF10369.9 CEH12620.1 - 0.04 14.1 0.1 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 Small subunit of acetolactate synthase S1 PF00575.23 CEH12620.1 - 0.05 13.9 0.5 0.23 11.8 0.5 2.1 1 1 0 1 1 1 0 S1 RNA binding domain Tex_YqgF PF16921.5 CEH12620.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Tex protein YqgF-like domain Ras PF00071.22 CEH12621.1 - 1.9e-24 86.1 0.0 2.1e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH12621.1 - 2.1e-13 50.5 0.0 2.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH12621.1 - 5.7e-05 22.6 0.0 6.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEH12621.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.6 CEH12621.1 - 0.023 14.3 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEH12621.1 - 0.041 14.4 0.0 0.061 13.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CEH12621.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region RRM_1 PF00076.22 CEH12622.1 - 2.1e-16 59.5 0.0 4.9e-07 29.5 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CbiK PF06180.11 CEH12623.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Abhydrolase_6 PF12697.7 CEH12623.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lyase_aromatic PF00221.19 CEH12625.1 - 4.4e-124 414.7 4.3 4.4e-124 414.7 4.3 1.8 1 1 1 2 2 2 1 Aromatic amino acid lyase Abhydrolase_6 PF12697.7 CEH12626.1 - 3.2e-09 37.7 2.4 3.2e-09 37.7 2.4 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEH12626.1 - 0.00082 19.1 0.0 0.39 10.3 0.0 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold Esterase PF00756.20 CEH12626.1 - 0.0097 15.6 0.0 0.0097 15.6 0.0 1.6 2 0 0 2 2 2 1 Putative esterase AMP-binding PF00501.28 CEH12627.1 - 4.6e-18 65.0 0.2 6.8e-18 64.5 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PI3_PI4_kinase PF00454.27 CEH12628.1 - 5.4e-53 180.4 0.0 8.7e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 CEH12628.1 - 1.5e-22 79.4 0.1 1.2e-21 76.6 0.0 2.7 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.23 CEH12628.1 - 1.8e-19 70.2 5.8 3.2e-19 69.4 5.8 1.3 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 CEH12628.1 - 2.6e-07 30.3 0.0 6.7e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 FATC domain GMC_oxred_C PF05199.13 CEH12628.1 - 0.82 10.2 2.9 1.3 9.6 0.6 2.5 3 0 0 3 3 3 0 GMC oxidoreductase SnoaL_4 PF13577.6 CEH12628.1 - 2.8 8.1 5.9 10 6.2 0.2 2.8 2 0 0 2 2 2 0 SnoaL-like domain CCB1 PF12046.8 CEH12629.1 - 0.062 12.6 0.0 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B Pro_isomerase PF00160.21 CEH12631.1 - 2.5e-46 157.8 0.4 3.9e-46 157.2 0.4 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CEH12631.1 - 7.3e-05 22.6 4.6 0.02 15.0 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEH12631.1 - 0.00018 21.1 2.1 0.36 10.7 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEH12631.1 - 0.0024 17.5 0.4 0.025 14.3 0.2 2.5 2 0 0 2 2 2 1 TPR repeat DUF5113 PF17140.4 CEH12631.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) TPR_9 PF13371.6 CEH12631.1 - 0.25 11.5 3.1 1.3 9.2 1.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEH12632.1 - 6.3e-22 76.4 0.5 7.7e-10 38.2 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEH12632.1 - 1.8e-18 65.1 0.6 1.8e-07 30.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEH12632.1 - 1.1e-16 60.2 4.0 5.4e-06 26.0 0.0 3.2 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 CEH12632.1 - 9.3e-16 56.7 1.3 1.8e-05 24.6 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEH12632.1 - 5.8e-10 39.1 1.4 0.015 16.1 0.0 4.0 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEH12632.1 - 8.2e-10 38.4 0.4 0.00061 20.0 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEH12632.1 - 6.7e-08 32.9 3.1 0.0012 19.3 0.1 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEH12632.1 - 7.2e-08 31.9 0.2 0.00049 19.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEH12632.1 - 3.2e-07 30.5 1.1 0.02 15.1 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEH12632.1 - 1.9e-06 28.4 6.7 9.8e-05 22.9 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CEH12632.1 - 1.2e-05 24.7 0.5 0.0016 17.7 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEH12632.1 - 0.00021 21.1 0.4 0.91 9.5 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEH12632.1 - 0.0043 17.2 0.0 0.068 13.3 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 CEH12632.1 - 0.078 13.1 0.8 11 6.2 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.12 CEH12632.1 - 0.11 12.3 0.5 1.6 8.4 0.1 2.4 1 1 2 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_6 PF13174.6 CEH12632.1 - 0.51 11.1 5.0 9.1 7.2 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Sel1 PF08238.12 CEH12633.1 - 2.9e-40 135.8 29.4 1.4e-07 31.9 1.2 8.2 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 CEH12633.1 - 0.00059 20.3 1.4 0.11 13.2 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 CEH12633.1 - 0.037 14.3 0.1 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat baeRF_family12 PF18856.1 CEH12633.1 - 0.17 12.5 0.0 0.66 10.5 0.0 2.0 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 TPR_19 PF14559.6 CEH12633.1 - 4.9 7.8 11.3 5.3 7.6 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat IF-2B PF01008.17 CEH12634.1 - 6.7e-61 206.0 0.0 1.2e-60 205.1 0.0 1.4 2 0 0 2 2 2 1 Initiation factor 2 subunit family SR-25 PF10500.9 CEH12634.1 - 2 7.9 12.6 3.2 7.3 12.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rtf2 PF04641.12 CEH12634.1 - 2.2 7.6 6.9 3.2 7.0 6.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger E1-N PF14463.6 CEH12635.1 - 0.053 13.3 1.4 0.093 12.5 1.4 1.4 1 0 0 1 1 1 0 E1 N-terminal domain MBF1 PF08523.10 CEH12636.1 - 6.3e-13 49.0 0.5 1.4e-12 47.8 0.5 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CEH12636.1 - 7.1e-12 45.2 0.5 1.2e-11 44.4 0.5 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 CEH12636.1 - 0.0067 16.4 0.2 0.0099 15.9 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 CEH12636.1 - 0.013 15.9 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain I-set PF07679.16 CEH12638.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Transposase_21 PF02992.14 CEH12640.1 - 0.087 12.1 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Transposase family tnp2 CLAG PF03805.13 CEH12650.1 - 0.21 9.2 0.1 0.26 8.8 0.1 1.0 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein Methyltransf_31 PF13847.6 CEH12652.1 - 8.2e-06 25.7 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH12652.1 - 0.00017 22.3 0.0 0.0003 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH12652.1 - 0.003 18.2 0.0 0.0052 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH12652.1 - 0.029 14.2 0.0 0.04 13.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PWI PF01480.17 CEH12653.1 - 6.1e-26 90.5 0.1 9.4e-26 89.9 0.1 1.2 1 0 0 1 1 1 1 PWI domain Fer2_3 PF13085.6 CEH12654.1 - 2.3e-32 111.2 0.0 4.2e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CEH12654.1 - 2.7e-09 37.4 6.4 2.7e-09 37.4 6.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CEH12654.1 - 7.8e-08 32.3 3.2 7.8e-08 32.3 3.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CEH12654.1 - 1.2e-07 32.1 6.6 1.2e-07 32.1 6.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 CEH12654.1 - 0.00054 20.5 3.0 0.00054 20.5 3.0 2.2 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CEH12654.1 - 0.014 15.3 1.0 0.014 15.3 1.0 2.1 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 CEH12654.1 - 0.94 9.7 0.1 0.94 9.7 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 CEH12654.1 - 3 8.1 14.7 0.33 11.1 8.2 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain WD40 PF00400.32 CEH12655.1 - 9.7e-17 61.1 15.7 0.034 15.0 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 CEH12655.1 - 2.7e-11 43.8 0.0 5.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain DUF4404 PF14357.6 CEH12656.1 - 0.11 13.2 1.5 2.2 9.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) VanZ PF04892.12 CEH12657.1 - 2.3e-05 25.1 0.4 4.4e-05 24.1 0.4 1.5 1 1 0 1 1 1 1 VanZ like family Acyl_transf_3 PF01757.22 CEH12657.1 - 0.41 9.6 5.3 0.14 11.2 1.9 1.4 1 1 1 2 2 2 0 Acyltransferase family Strabismus PF06638.11 CEH12657.1 - 1 7.9 3.7 1.6 7.3 3.7 1.1 1 0 0 1 1 1 0 Strabismus protein Peptidase_M28 PF04389.17 CEH12658.1 - 3.4e-38 131.3 0.0 5e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CEH12658.1 - 9.6e-14 51.2 2.5 1.6e-13 50.5 1.7 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 CEH12658.1 - 0.00018 21.2 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 VPS9 PF02204.18 CEH12659.1 - 5.4e-29 100.5 0.0 8.8e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CEH12659.1 - 4.7e-11 42.8 0.3 1.4e-10 41.3 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 CEH12659.1 - 1.8e-08 33.9 0.0 3.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 CEH12659.1 - 5.8e-07 29.0 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif SNARE PF05739.19 CEH12659.1 - 0.16 12.0 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 SNARE domain SYF2 PF08231.12 CEH12660.1 - 1e-43 149.5 8.6 1e-43 149.5 8.6 2.0 2 0 0 2 2 2 1 SYF2 splicing factor Annexin PF00191.20 CEH12661.1 - 1.8e-52 175.2 0.5 3.1e-15 56.0 0.0 4.3 4 1 0 4 4 4 4 Annexin DUF5617 PF18493.1 CEH12661.1 - 0.062 13.4 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) DUF1168 PF06658.12 CEH12663.1 - 9.1e-36 122.7 23.6 5.1e-35 120.2 23.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) BAF1_ABF1 PF04684.13 CEH12663.1 - 0.4 9.7 6.9 0.42 9.6 6.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RskA PF10099.9 CEH12663.1 - 2.6 8.3 15.7 0.6 10.4 12.3 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA XRN_M PF17846.1 CEH12663.1 - 6.4 5.6 6.8 8.7 5.2 6.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain SAPS PF04499.15 CEH12663.1 - 9.3 4.9 8.2 13 4.4 8.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.6 CEH12663.1 - 10 5.4 12.6 14 5.0 12.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Methyltrans_RNA PF04452.14 CEH12665.1 - 0.28 10.5 0.6 0.32 10.3 0.1 1.4 2 0 0 2 2 2 0 RNA methyltransferase Arf PF00025.21 CEH12666.1 - 1.2e-73 246.3 0.1 1.3e-73 246.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEH12666.1 - 7.1e-15 55.3 0.0 9.7e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CEH12666.1 - 5.6e-14 52.1 0.7 4.2e-09 36.0 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CEH12666.1 - 1.3e-13 50.8 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CEH12666.1 - 2e-13 50.2 0.0 2.3e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CEH12666.1 - 1.5e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEH12666.1 - 1.5e-05 25.1 0.0 2.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH12666.1 - 0.012 15.2 0.3 0.027 14.0 0.3 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 CEH12666.1 - 0.037 13.9 0.4 0.088 12.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 CEH12666.1 - 0.049 12.6 0.3 0.22 10.5 0.3 2.0 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CEH12666.1 - 0.084 12.5 0.6 0.33 10.5 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain WD40 PF00400.32 CEH12667.1 - 3.2e-06 27.8 5.0 0.021 15.7 0.8 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat PPR_2 PF13041.6 CEH12668.1 - 8.6e-28 96.3 0.0 4.4e-07 30.0 0.0 6.9 6 1 2 8 8 8 6 PPR repeat family PPR PF01535.20 CEH12668.1 - 1.9e-19 68.5 3.5 0.0024 18.0 0.0 8.8 9 0 0 9 9 9 5 PPR repeat PPR_1 PF12854.7 CEH12668.1 - 4.5e-16 58.3 0.0 0.0023 17.6 0.0 6.1 6 0 0 6 6 6 3 PPR repeat PPR_3 PF13812.6 CEH12668.1 - 2.3e-10 40.4 0.0 9.8e-06 25.6 0.0 4.2 3 1 2 5 5 5 4 Pentatricopeptide repeat domain PPR_long PF17177.4 CEH12668.1 - 2e-05 24.1 0.0 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PH_9 PF15410.6 CEH12669.1 - 1.4e-25 90.0 0.0 2.9e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 CEH12669.1 - 5.7e-25 88.1 0.0 9.9e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Response_reg PF00072.24 CEH12670.1 - 7.1e-19 68.0 0.3 2.6e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 CEH12670.1 - 6.9e-12 45.9 2.8 3.6e-11 43.6 0.0 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CEH12670.1 - 4.8e-09 36.1 0.4 2.2e-08 34.0 0.3 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 CEH12670.1 - 0.022 15.1 0.2 0.32 11.3 0.2 2.8 1 1 0 1 1 1 0 GAF domain DUF3731 PF12531.8 CEH12670.1 - 0.094 12.5 0.3 0.22 11.3 0.3 1.5 1 0 0 1 1 1 0 DNA-K related protein CcdA PF07362.12 CEH12670.1 - 1 9.8 3.5 13 6.3 0.1 3.1 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Longin PF13774.6 CEH12671.1 - 5.7e-21 74.3 0.0 8.8e-21 73.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CEH12671.1 - 1e-14 54.1 0.1 1.9e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Synaptobrevin E1-E2_ATPase PF00122.20 CEH12671.1 - 0.17 11.4 0.3 0.71 9.4 0.1 1.9 2 0 0 2 2 2 0 E1-E2 ATPase ANTH PF07651.16 CEH12672.1 - 5e-73 245.5 0.0 2.5e-72 243.2 0.0 2.3 1 0 0 1 1 1 1 ANTH domain I_LWEQ PF01608.17 CEH12672.1 - 2.3e-55 187.0 12.1 2.3e-55 187.0 12.1 5.7 4 2 1 6 6 6 1 I/LWEQ domain ENTH PF01417.20 CEH12672.1 - 0.00025 21.1 0.0 0.0027 17.8 0.0 2.8 2 0 0 2 2 2 1 ENTH domain TcdB_N PF12918.7 CEH12672.1 - 0.0099 16.1 0.3 0.031 14.6 0.3 1.9 1 0 0 1 1 1 1 TcdB toxin N-terminal helical domain Pox_A21 PF05323.12 CEH12673.1 - 0.16 12.6 0.0 0.36 11.4 0.0 1.7 1 0 0 1 1 1 0 Poxvirus A21 Protein Med15_fungi PF05397.12 CEH12674.1 - 1e-22 80.5 0.1 1e-22 80.5 0.1 3.7 3 0 0 3 3 3 1 Mediator complex subunit 15 ARID PF01388.21 CEH12674.1 - 3.6e-13 50.0 0.0 1.4e-12 48.1 0.0 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain ABC2_membrane PF01061.24 CEH12676.1 - 2.1e-34 118.8 16.4 2.1e-34 118.8 16.4 2.1 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 CEH12676.1 - 1.5e-22 80.6 0.0 2.6e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CEH12676.1 - 9.2e-05 22.4 0.7 0.069 12.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CEH12676.1 - 0.003 17.5 0.1 0.0058 16.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CEH12676.1 - 0.015 15.7 0.1 0.03 14.7 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 CEH12676.1 - 0.035 14.3 0.2 0.27 11.5 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_3 PF12698.7 CEH12676.1 - 0.049 12.7 20.8 0.1 11.7 20.8 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_29 PF13555.6 CEH12676.1 - 0.1 12.4 0.3 0.26 11.1 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2207 PF09972.9 CEH12676.1 - 1.5 7.5 0.0 1.5 7.5 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) ubiquitin PF00240.23 CEH12677.1 - 0.0043 16.8 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CEH12677.1 - 0.0069 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CEH12677.1 - 0.0077 16.8 0.1 0.032 14.8 0.0 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Flg_hook PF02120.16 CEH12677.1 - 0.15 11.9 0.6 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK DASH_Spc19 PF08287.11 CEH12678.1 - 2.2e-29 102.4 8.1 2.9e-29 102.0 8.1 1.2 1 0 0 1 1 1 1 Spc19 Caprin-1_dimer PF18293.1 CEH12678.1 - 0.035 14.6 1.3 0.072 13.6 1.3 1.6 1 1 0 1 1 1 0 Caprin-1 dimerization domain Taxilin PF09728.9 CEH12678.1 - 0.036 13.3 7.1 0.05 12.8 7.1 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein FAD-SLDH PF12318.8 CEH12678.1 - 0.42 10.7 6.6 0.26 11.3 2.8 2.3 1 1 2 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase SLIDE PF09111.10 CEH12678.1 - 0.63 10.1 3.5 2.4 8.2 0.8 2.1 2 0 0 2 2 2 0 SLIDE Lzipper-MIP1 PF14389.6 CEH12678.1 - 0.75 10.1 12.3 3.4 8.0 7.6 3.3 2 1 2 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 RPS31 PF17067.5 CEH12678.1 - 0.91 9.7 3.9 1.7 8.9 3.9 1.4 1 0 0 1 1 1 0 Ribosomal protein S31e DUF1843 PF08898.10 CEH12678.1 - 1.3 9.6 0.0 1.3 9.6 0.0 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF1843) Bromodomain PF00439.25 CEH12679.1 - 2.4e-16 59.6 0.0 4e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain SOG2 PF10428.9 CEH12681.1 - 4.8 6.3 8.1 6.7 5.8 8.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein IGR PF09597.10 CEH12682.1 - 5.4e-05 23.2 0.0 0.00027 21.0 0.0 2.1 2 0 0 2 2 2 1 IGR protein motif Ank_2 PF12796.7 CEH12683.1 - 5.6e-34 116.6 4.7 1.1e-12 48.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEH12683.1 - 9.1e-27 90.2 0.3 0.00021 21.5 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 CEH12683.1 - 1.4e-26 91.7 2.4 7.9e-06 26.1 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 CEH12683.1 - 9.1e-25 86.7 1.6 2.3e-07 31.2 0.0 5.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEH12683.1 - 7.1e-22 77.2 3.1 8.7e-09 35.5 0.1 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Glyoxalase_6 PF18029.1 CEH12683.1 - 0.021 15.6 2.0 4.4 8.1 0.3 3.0 2 1 0 2 2 2 0 Glyoxalase-like domain DUF3459 PF11941.8 CEH12683.1 - 0.058 13.7 0.2 0.16 12.3 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) DIM1 PF02966.16 CEH12684.1 - 1.5e-65 218.9 0.0 1.7e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CEH12684.1 - 0.013 15.5 0.1 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin Urm1 PF09138.11 CEH12685.1 - 3.7e-24 84.9 0.0 3.4e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CEH12685.1 - 0.0017 18.9 0.0 0.0033 18.0 0.0 1.5 1 0 0 1 1 1 1 ThiS family MRP-L20 PF12824.7 CEH12689.1 - 3.8e-29 102.0 4.3 7e-29 101.1 4.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Pyr_redox_2 PF07992.14 CEH12689.1 - 1.3e-09 37.7 0.0 1.8e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HTH_11 PF08279.12 CEH12689.1 - 0.0094 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_32 PF13565.6 CEH12689.1 - 0.015 15.9 0.3 0.043 14.4 0.3 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Neugrin PF06413.11 CEH12689.1 - 0.029 14.4 0.1 0.053 13.5 0.1 1.4 1 0 0 1 1 1 0 Neugrin DcpS_C PF11969.8 CEH12690.1 - 2.7e-13 50.4 3.8 2.7e-08 34.3 0.5 3.0 3 0 0 3 3 3 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CEH12690.1 - 6.6e-11 42.8 0.3 1.2e-05 26.0 0.1 2.3 2 0 0 2 2 2 2 HIT domain zf-C2HE PF16278.5 CEH12690.1 - 9.7e-08 32.4 0.8 3.3e-07 30.7 0.3 2.2 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger Alginate_lyase PF05426.12 CEH12691.1 - 1.5e-53 182.1 3.4 6.7e-53 180.0 1.0 2.1 2 0 0 2 2 2 2 Alginate lyase Ank_2 PF12796.7 CEH12692.1 - 3.7e-16 59.5 0.1 9.2e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEH12692.1 - 3.9e-13 48.3 3.0 0.0017 18.7 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 CEH12692.1 - 3.9e-13 49.6 0.5 4.8e-11 43.0 0.2 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEH12692.1 - 1.4e-12 47.6 1.2 2e-05 24.8 0.1 4.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CEH12692.1 - 1.1e-11 44.6 4.9 0.00032 21.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Spem1 PF15670.5 CEH12693.1 - 0.0023 17.6 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Spermatid maturation protein 1 DUF2613 PF11021.8 CEH12693.1 - 0.14 12.3 0.0 0.49 10.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) zf-C2H2 PF00096.26 CEH12694.1 - 2e-08 34.2 14.2 0.00059 20.2 3.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEH12694.1 - 7.1e-08 32.5 20.2 8.7e-05 22.8 5.3 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEH12694.1 - 0.043 14.7 2.1 0.043 14.7 2.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 CEH12694.1 - 0.058 14.0 0.5 0.058 14.0 0.5 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain TFIIA PF03153.13 CEH12695.1 - 1.3e-47 163.7 29.2 2.8e-29 103.4 18.4 3.1 2 1 1 3 3 3 2 Transcription factor IIA, alpha/beta subunit YL1_C PF08265.11 CEH12695.1 - 5e-16 58.2 0.1 8.6e-16 57.4 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Mer2 PF09074.10 CEH12697.1 - 6 6.6 8.4 3.2 7.5 5.1 2.0 1 1 1 2 2 2 0 Mer2 TRAM_LAG1_CLN8 PF03798.16 CEH12698.1 - 5.6e-06 26.2 13.3 7.7e-06 25.8 13.3 1.2 1 0 0 1 1 1 1 TLC domain DUF3391 PF11871.8 CEH12698.1 - 1.5 9.3 4.2 4.2 7.9 4.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) adh_short PF00106.25 CEH12699.1 - 3.3e-22 78.9 0.0 7.1e-22 77.8 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH12699.1 - 9.5e-18 64.6 0.0 3.6e-17 62.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH12699.1 - 0.0053 16.7 3.6 0.095 12.6 2.6 2.6 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 CEH12699.1 - 0.011 15.2 0.7 0.04 13.4 0.7 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 CEH12699.1 - 0.022 15.0 0.6 0.043 14.1 0.6 1.5 1 0 0 1 1 1 0 TrkA-N domain DFP PF04127.15 CEH12699.1 - 0.073 12.9 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein SSF PF00474.17 CEH12701.1 - 5.5e-19 68.3 30.5 5.5e-19 68.3 30.5 1.9 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2839 PF10999.8 CEH12701.1 - 0.22 11.9 0.0 0.22 11.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) EIF_2_alpha PF07541.12 CEH12702.1 - 3.1e-38 130.4 0.3 1.6e-37 128.2 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CEH12702.1 - 4.4e-14 52.6 1.3 1.1e-13 51.3 1.3 1.7 1 0 0 1 1 1 1 S1 RNA binding domain RhoGEF PF00621.20 CEH12704.1 - 1.2e-29 103.9 0.0 1.8e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Transcrip_reg PF01709.20 CEH12706.1 - 7.9e-41 140.0 3.2 3e-32 112.0 0.2 3.0 1 1 1 2 2 2 2 Transcriptional regulator DUF2841 PF11001.8 CEH12707.1 - 2.3e-38 131.0 0.3 3.7e-38 130.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) NOB1_Zn_bind PF08772.11 CEH12711.1 - 9.5e-24 83.4 0.7 1.7e-23 82.5 0.7 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 CEH12711.1 - 3.5e-21 75.5 0.3 1.1e-20 73.9 0.3 1.9 1 0 0 1 1 1 1 PIN domain of ribonuclease PIN_4 PF13638.6 CEH12711.1 - 0.00078 19.7 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 PIN domain DZR PF12773.7 CEH12711.1 - 0.015 15.3 1.4 0.026 14.5 1.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon FliJ PF02050.16 CEH12711.1 - 0.022 15.0 0.1 0.022 15.0 0.1 1.7 2 0 0 2 2 2 0 Flagellar FliJ protein zf-NADH-PPase PF09297.11 CEH12711.1 - 0.091 12.4 4.7 4 7.2 0.1 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Sec62 PF03839.16 CEH12712.1 - 4.5e-51 173.4 4.2 3.9e-50 170.4 4.2 2.0 1 1 0 1 1 1 1 Translocation protein Sec62 Glyco_tran_28_C PF04101.16 CEH12713.1 - 4.1e-17 62.7 0.1 1.3e-13 51.2 0.0 2.6 3 0 0 3 3 3 2 Glycosyltransferase family 28 C-terminal domain Presenilin PF01080.17 CEH12713.1 - 0.93 8.2 2.7 1.3 7.7 2.7 1.1 1 0 0 1 1 1 0 Presenilin MutS_V PF00488.21 CEH12714.1 - 1.2e-75 253.8 0.0 3e-75 252.4 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CEH12714.1 - 1.1e-31 110.6 2.2 1.4e-31 110.2 0.6 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CEH12714.1 - 5.9e-19 68.7 0.4 6e-18 65.4 0.0 2.8 4 0 0 4 4 4 1 MutS domain II MutS_IV PF05190.18 CEH12714.1 - 6.1e-17 61.7 0.5 1.4e-16 60.6 0.1 1.9 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 CEH12714.1 - 7.6e-11 42.3 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 CEH12714.1 - 0.078 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CEH12714.1 - 0.12 12.3 0.5 42 4.0 0.0 3.2 3 0 0 3 3 3 0 NTPase Adap_comp_sub PF00928.21 CEH12716.1 - 5.7e-83 278.3 0.0 7e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CEH12716.1 - 0.00066 19.6 0.5 0.0011 18.9 0.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_M48 PF01435.18 CEH12717.1 - 3.4e-30 105.3 0.1 6.5e-30 104.4 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M48 Kelch_2 PF07646.15 CEH12717.1 - 0.089 12.8 0.2 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Kelch motif SPX PF03105.19 CEH12719.1 - 7.2e-67 227.0 44.9 1.7e-41 143.5 35.7 3.2 1 1 0 2 2 2 2 SPX domain DUF953 PF06110.11 CEH12721.1 - 9e-10 38.2 0.0 1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 CEH12721.1 - 7.2e-06 25.9 0.0 9.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CEH12721.1 - 0.0071 16.6 0.0 0.15 12.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CEH12721.1 - 0.0083 16.6 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CEH12721.1 - 0.0089 15.8 0.0 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin PNRC PF15365.6 CEH12722.1 - 9.7e-06 25.2 6.3 9.7e-06 25.2 6.3 3.1 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif RPA43_OB PF17875.1 CEH12722.1 - 1.2 9.8 4.7 0.25 12.0 0.9 1.9 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Ank_2 PF12796.7 CEH12723.1 - 7.5e-39 132.2 7.8 8.1e-15 55.2 0.0 3.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEH12723.1 - 4.1e-22 78.2 5.0 4e-06 27.3 0.1 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CEH12723.1 - 7e-22 76.9 15.1 2.1e-06 27.9 0.2 6.7 6 0 0 6 6 6 3 Ankyrin repeat DHHC PF01529.20 CEH12723.1 - 2.1e-20 73.2 24.6 4.5e-11 43.0 8.7 2.5 2 0 0 2 2 2 2 DHHC palmitoyltransferase Ank_5 PF13857.6 CEH12723.1 - 9.7e-20 70.4 2.0 1.4e-06 28.5 0.1 4.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEH12723.1 - 1.7e-18 64.8 6.7 0.00051 20.3 0.1 6.3 6 0 0 6 6 6 4 Ankyrin repeat Spb1_C PF07780.12 CEH12725.1 - 4.1e-73 245.5 31.9 4.1e-73 245.5 31.9 3.4 3 2 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 CEH12725.1 - 5.1e-54 183.1 0.0 8.6e-54 182.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CEH12725.1 - 2.8e-41 141.1 2.7 2.8e-41 141.1 2.7 6.5 5 1 0 5 5 5 1 Domain of unknown function (DUF3381) SET PF00856.28 CEH12726.1 - 1.5e-07 31.9 0.3 5.5e-07 30.1 0.1 2.1 2 1 0 2 2 2 1 SET domain RecX PF02631.16 CEH12726.1 - 0.031 14.7 0.0 0.076 13.5 0.0 1.6 1 0 0 1 1 1 0 RecX family tRNA-synt_1 PF00133.22 CEH12727.1 - 7.1e-221 734.6 0.0 3.8e-220 732.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CEH12727.1 - 5.5e-23 81.6 0.0 1.4e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CEH12727.1 - 1.3e-15 57.1 0.7 2.7e-05 23.1 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA_anti-codon PF01336.25 CEH12728.1 - 7.4e-09 35.5 0.1 1.5e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 CEH12728.1 - 1.1e-08 35.6 0.4 1e-07 32.6 0.1 2.2 2 0 0 2 2 2 1 Replication protein A C terminal RMI2 PF16100.5 CEH12728.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 B12D PF06522.11 CEH12729.1 - 2.3e-22 78.5 0.3 2.7e-22 78.3 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit EST1_DNA_bind PF10373.9 CEH12730.1 - 5e-32 111.5 0.0 3e-31 109.0 0.0 2.0 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CEH12730.1 - 6.3e-17 62.5 0.1 4.5e-16 59.7 0.0 2.4 2 0 0 2 2 2 1 Telomerase activating protein Est1 ATP-synt_F PF01990.17 CEH12731.1 - 2.6e-29 101.4 0.0 3e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit EF-hand_7 PF13499.6 CEH12733.1 - 8.9e-27 93.3 9.9 2.5e-15 56.7 2.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CEH12733.1 - 9.6e-26 87.4 13.9 2.6e-09 35.9 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CEH12733.1 - 5.2e-23 79.0 9.8 3.8e-08 32.6 0.1 5.0 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CEH12733.1 - 1.5e-16 60.0 12.3 6.3e-09 35.6 1.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CEH12733.1 - 1.3e-15 56.1 12.8 1.8e-05 24.0 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CEH12733.1 - 5.3e-10 39.5 0.8 0.001 19.3 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CEH12733.1 - 1.8e-07 31.0 1.0 0.00087 19.2 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CEH12733.1 - 0.00046 20.2 0.4 0.043 13.8 0.0 3.1 1 1 3 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 CEH12733.1 - 0.011 16.0 0.1 5.7 7.3 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CEH12733.1 - 0.071 13.3 3.2 0.48 10.6 0.1 3.0 2 1 0 2 2 2 0 Dockerin type I domain TauD PF02668.16 CEH12734.1 - 1.1e-45 156.5 0.5 1.7e-45 155.9 0.5 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AZUL PF16558.5 CEH12734.1 - 0.085 13.1 2.5 0.2 11.9 2.5 1.5 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A GST_C_3 PF14497.6 CEH12735.1 - 3e-09 37.0 0.0 4.6e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CEH12735.1 - 6.9e-09 36.0 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEH12735.1 - 3.1e-08 33.8 0.0 5.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEH12735.1 - 8.8e-05 22.8 0.0 0.00044 20.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEH12735.1 - 0.0035 17.3 0.0 0.0085 16.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEH12735.1 - 0.03 14.5 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF836 PF05768.14 CEH12735.1 - 0.18 12.3 0.0 9.2 6.8 0.0 2.4 2 1 0 2 2 2 0 Glutaredoxin-like domain (DUF836) FBPase PF00316.20 CEH12736.1 - 3.4e-73 245.2 0.5 5e-73 244.6 0.5 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 CEH12736.1 - 0.0011 18.6 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family SPX PF03105.19 CEH12739.1 - 1.1e-37 130.8 0.1 3.4e-24 86.5 0.0 2.4 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 CEH12739.1 - 3.6e-29 101.9 59.0 8.6e-25 87.5 33.2 2.1 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 CEH12739.1 - 4.8e-28 98.4 34.6 7e-28 97.9 34.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region YbhQ PF11076.8 CEH12739.1 - 5.6 7.0 7.2 2.7 8.0 1.3 2.9 3 0 0 3 3 3 0 Putative inner membrane protein YbhQ Rot1 PF10681.9 CEH12740.1 - 1.1e-55 188.5 1.2 1.3e-55 188.1 1.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF5640 PF18692.1 CEH12740.1 - 0.16 12.0 0.4 0.97 9.5 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5640) CKS PF01111.19 CEH12741.1 - 2.3e-34 117.5 1.7 3.2e-34 117.0 1.7 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Dcc1 PF09724.9 CEH12741.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 SNF2_N PF00176.23 CEH12742.1 - 1.6e-60 204.7 0.0 4.4e-60 203.2 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEH12742.1 - 7.4e-16 58.5 0.0 1.8e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH12742.1 - 5.4e-10 39.5 0.0 1.3e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEH12742.1 - 1.2e-06 28.4 0.0 3.6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 CEH12742.1 - 0.00011 21.5 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Prefoldin PF02996.17 CEH12743.1 - 0.0052 16.7 5.1 0.013 15.4 0.6 2.4 2 1 0 2 2 2 2 Prefoldin subunit BHD_3 PF10405.9 CEH12744.1 - 4.6e-28 97.4 0.1 8.6e-28 96.6 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 CEH12744.1 - 3e-24 85.4 0.2 3e-24 85.4 0.2 2.4 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 CEH12744.1 - 2.2e-16 60.5 0.4 2.2e-16 60.5 0.4 5.9 6 1 0 6 6 6 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 CEH12744.1 - 7.1e-16 57.8 0.0 1.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 CEH12744.1 - 1.3e-05 25.6 0.5 7.9e-05 23.1 0.1 2.5 2 0 0 2 2 2 1 Transglutaminase-like superfamily PACT_coil_coil PF10495.9 CEH12744.1 - 0.23 12.1 2.6 0.5 11.0 0.1 3.0 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein COG7 PF10191.9 CEH12745.1 - 1.3e-42 146.1 0.1 2.9e-23 82.1 0.0 4.1 4 0 0 4 4 4 4 Golgi complex component 7 (COG7) DUF726 PF05277.12 CEH12746.1 - 2.2e-50 171.5 0.5 2e-35 122.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF726) DUF3089 PF11288.8 CEH12746.1 - 0.012 15.2 0.0 0.034 13.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2207 PF09972.9 CEH12746.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Brix PF04427.18 CEH12748.1 - 1.2e-19 71.2 0.0 2.5e-17 63.6 0.0 2.3 1 1 0 1 1 1 1 Brix domain Zn_clus PF00172.18 CEH12749.1 - 1.8e-05 24.8 5.2 3.9e-05 23.7 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_21 PF13506.6 CEH12750.1 - 5.8e-20 71.5 0.1 6e-08 32.3 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CEH12750.1 - 2.6e-13 50.4 0.0 4.8e-12 46.2 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF2474 PF10617.9 CEH12750.1 - 0.033 14.0 1.7 0.13 12.2 1.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) WW PF00397.26 CEH12752.1 - 2.5e-07 30.7 0.7 4.3e-07 29.9 0.7 1.4 1 0 0 1 1 1 1 WW domain Trnau1ap PF17654.1 CEH12752.1 - 1.8 9.4 11.3 5.5 7.9 0.6 2.3 2 0 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins Amidohydro_1 PF01979.20 CEH12753.1 - 5.6e-53 180.4 0.0 2.7e-23 82.9 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_3 PF07969.11 CEH12753.1 - 0.0033 16.9 0.1 1.4 8.3 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family TFIID-18kDa PF02269.16 CEH12754.1 - 1.3e-29 102.1 0.3 2.3e-28 98.1 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Adaptin_binding PF10199.9 CEH12754.1 - 0.0066 17.1 0.9 0.0066 17.1 0.9 2.1 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 TFIIE-A_C PF11521.8 CEH12754.1 - 0.024 15.0 1.0 0.067 13.5 1.0 1.8 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha MutS_II PF05188.17 CEH12754.1 - 0.16 12.3 1.6 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 MutS domain II Pkinase PF00069.25 CEH12755.1 - 3.8e-59 200.2 0.0 5.4e-57 193.1 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH12755.1 - 2.8e-22 79.2 0.0 8.6e-22 77.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH12755.1 - 0.00021 20.7 0.0 0.00032 20.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CEH12755.1 - 0.03 14.2 0.1 0.16 11.9 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEH12755.1 - 0.087 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 CEH12755.1 - 0.095 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CoA_binding_2 PF13380.6 CEH12756.1 - 2.1e-28 99.2 0.0 2.4e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain GDI PF00996.18 CEH12757.1 - 1.2e-205 683.1 0.0 1.4e-205 682.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CEH12757.1 - 0.0082 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ribosomal_S15 PF00312.22 CEH12758.1 - 4.8e-22 78.0 0.2 4.8e-22 78.0 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 SpoU_methylas_C PF12105.8 CEH12758.1 - 0.021 14.5 0.2 0.044 13.5 0.2 1.5 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal ETF_QO PF05187.13 CEH12759.1 - 2.8e-40 136.6 0.0 4.6e-40 135.9 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CEH12759.1 - 1.3e-06 28.3 1.4 0.00099 18.8 1.3 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEH12759.1 - 4.8e-06 26.7 0.1 2.1e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CEH12759.1 - 2.5e-05 23.5 2.0 0.00021 20.5 1.6 2.1 1 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CEH12759.1 - 5.2e-05 22.6 0.0 8.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEH12759.1 - 0.00012 20.9 0.8 0.00023 20.0 0.8 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 CEH12759.1 - 0.00048 19.4 0.2 0.00093 18.5 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 CEH12759.1 - 0.00062 18.9 0.1 0.0011 18.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CEH12759.1 - 0.0017 17.7 0.9 0.0027 17.0 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEH12759.1 - 0.0021 18.0 0.3 0.0042 17.1 0.3 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 CEH12759.1 - 0.0041 16.4 0.3 0.0072 15.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CEH12759.1 - 0.0055 16.1 0.6 0.0087 15.5 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4_7 PF12838.7 CEH12759.1 - 0.028 15.0 0.8 0.064 13.8 0.8 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pyr_redox PF00070.27 CEH12759.1 - 0.14 12.8 0.4 9.2 6.9 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEH12759.1 - 0.16 11.0 0.5 0.24 10.4 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 CEH12759.1 - 0.17 10.7 2.1 0.12 11.2 0.5 1.5 2 0 0 2 2 2 0 Tryptophan halogenase zf-RING_2 PF13639.6 CEH12760.1 - 1.3e-08 35.0 8.8 2e-08 34.4 8.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEH12760.1 - 6.3e-06 25.8 7.3 1e-05 25.1 7.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CEH12760.1 - 2e-05 24.5 8.6 3e-05 23.9 8.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEH12760.1 - 2.8e-05 23.9 7.8 4e-05 23.4 7.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEH12760.1 - 5.6e-05 22.9 9.2 9e-05 22.2 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEH12760.1 - 0.0074 16.1 8.8 0.012 15.5 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEH12760.1 - 0.065 13.5 7.9 0.46 10.8 7.9 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CEH12760.1 - 0.12 12.4 9.7 0.24 11.4 9.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CEH12760.1 - 0.92 9.2 4.8 1.5 8.5 4.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CEH12760.1 - 9.3 6.2 9.3 15 5.6 9.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 WD40 PF00400.32 CEH12761.1 - 7.2e-45 150.1 12.4 9e-09 35.8 0.6 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH12761.1 - 8.9e-15 54.8 1.5 0.00041 20.6 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEH12761.1 - 0.00064 18.5 2.3 1.4 7.5 0.0 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 LisH PF08513.11 CEH12761.1 - 0.018 15.0 0.3 0.032 14.2 0.3 1.4 1 0 0 1 1 1 0 LisH eIF2A PF08662.11 CEH12761.1 - 0.037 13.9 0.0 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A VWA_3_C PF18571.1 CEH12761.1 - 0.12 12.3 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain Rootletin PF15035.6 CEH12761.1 - 0.18 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Nucleoporin_N PF08801.11 CEH12761.1 - 0.19 10.4 0.0 1.8 7.2 0.0 2.4 3 0 0 3 3 3 0 Nup133 N terminal like Ge1_WD40 PF16529.5 CEH12761.1 - 2.2 7.2 11.5 18 4.1 4.2 3.9 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pirin PF02678.16 CEH12762.1 - 4.5e-28 97.4 0.2 9.5e-28 96.3 0.2 1.5 1 0 0 1 1 1 1 Pirin RibD_C PF01872.17 CEH12762.1 - 8.7e-27 94.3 0.1 3.3e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 RibD C-terminal domain Cupin_2 PF07883.11 CEH12762.1 - 4.1e-08 32.8 1.5 4.1e-06 26.4 0.3 3.1 3 0 0 3 3 3 2 Cupin domain His_Phos_1 PF00300.22 CEH12763.1 - 7.8e-33 113.8 0.1 5.1e-29 101.4 0.1 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) JmjC PF02373.22 CEH12764.1 - 4.1e-14 53.0 0.0 9e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase FYVE PF01363.21 CEH12764.1 - 0.0009 19.3 4.0 0.0032 17.6 4.0 1.9 1 0 0 1 1 1 1 FYVE zinc finger zinc-ribbon_6 PF10005.9 CEH12764.1 - 0.021 15.5 2.4 0.021 15.5 2.4 2.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-B_box PF00643.24 CEH12764.1 - 0.028 14.6 4.2 0.065 13.4 4.2 1.6 1 0 0 1 1 1 0 B-box zinc finger Cupin_8 PF13621.6 CEH12764.1 - 0.056 13.1 0.0 0.56 9.9 0.0 2.5 1 1 0 1 1 1 0 Cupin-like domain PRP1_N PF06424.12 CEH12766.1 - 1.4e-50 171.6 3.9 5.1e-50 169.7 3.9 2.0 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CEH12766.1 - 6.3e-25 85.7 37.3 0.019 15.7 0.0 13.4 6 5 8 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 CEH12766.1 - 3.8e-17 62.6 22.7 0.011 16.2 1.5 8.7 9 1 0 9 9 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 CEH12766.1 - 6.5e-09 35.2 2.6 0.013 15.5 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEH12766.1 - 5.1e-05 23.2 0.2 0.042 14.1 0.0 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEH12766.1 - 0.00026 21.6 29.5 1.4 9.6 3.0 7.9 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEH12766.1 - 0.013 15.9 1.1 39 4.9 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEH12766.1 - 0.038 13.8 0.0 9.9 6.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEH12766.1 - 0.078 13.7 16.5 19 6.2 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEH12766.1 - 0.19 12.1 11.3 2 8.7 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Suf PF05843.14 CEH12766.1 - 0.39 10.7 6.4 48 3.8 0.0 5.5 6 1 0 6 6 6 0 Suppressor of forked protein (Suf) LSM PF01423.22 CEH12767.1 - 7.3e-21 73.6 0.0 8e-21 73.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEH12767.1 - 0.00061 19.9 0.0 0.00076 19.6 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain RNase_Zc3h12a PF11977.8 CEH12767.1 - 0.16 11.8 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain AA_permease PF00324.21 CEH12768.1 - 3.1e-85 286.6 35.4 4e-85 286.2 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEH12768.1 - 5e-21 75.0 34.4 7.1e-21 74.5 34.4 1.2 1 0 0 1 1 1 1 Amino acid permease SKN1 PF03935.15 CEH12769.1 - 4.3e-84 282.7 0.0 5.1e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 CEH12770.1 - 6.5e-85 285.4 0.0 8.7e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Cytochrom_B561 PF03188.16 CEH12771.1 - 4e-15 56.2 6.9 4e-15 56.2 6.9 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Cyclin PF08613.11 CEH12772.1 - 4.8e-06 27.0 0.0 1.3e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Cyclin KH_1 PF00013.29 CEH12774.1 - 7.4e-42 141.0 11.9 9.5e-17 60.6 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CEH12774.1 - 3.9e-11 42.6 5.5 0.0038 17.0 0.1 3.6 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CEH12774.1 - 5.2e-09 35.8 0.6 0.097 12.6 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CEH12774.1 - 0.00065 19.7 4.8 0.085 12.9 0.1 3.4 3 0 0 3 3 3 1 NusA-like KH domain CLASP_N PF12348.8 CEH12775.1 - 5.6e-22 78.4 0.0 2.5e-07 30.5 0.0 4.5 4 0 0 4 4 4 4 CLASP N terminal HEAT_2 PF13646.6 CEH12775.1 - 1e-12 48.3 11.9 0.0026 18.1 0.0 7.9 6 2 1 7 7 7 4 HEAT repeats HEAT PF02985.22 CEH12775.1 - 2.2e-12 46.1 4.5 0.023 14.9 0.0 7.6 8 0 0 8 8 8 3 HEAT repeat Cnd1 PF12717.7 CEH12775.1 - 2.1e-07 31.1 0.0 1.6 8.7 0.0 6.7 6 2 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CEH12775.1 - 4.3e-05 23.9 2.8 1.1 9.8 0.1 5.7 4 0 0 4 4 4 1 HEAT-like repeat RTP1_C1 PF10363.9 CEH12775.1 - 0.00084 19.5 0.1 18 5.5 0.0 5.0 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 CEH12775.1 - 0.0025 16.5 0.1 5.1 5.5 0.0 3.8 4 0 0 4 4 4 2 Adaptin N terminal region TAN PF11640.8 CEH12775.1 - 0.0073 16.4 0.1 20 5.3 0.0 5.0 5 0 0 5 5 5 0 Telomere-length maintenance and DNA damage repair Cohesin_HEAT PF12765.7 CEH12775.1 - 0.069 13.5 1.1 24 5.3 0.2 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Pex2_Pex12 PF04757.14 CEH12776.1 - 1.9e-32 112.7 2.2 2.9e-32 112.1 2.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region SPX PF03105.19 CEH12776.1 - 3.7 7.4 5.5 7.6 6.3 5.5 1.5 1 0 0 1 1 1 0 SPX domain SH3_1 PF00018.28 CEH12777.1 - 1.3e-11 43.9 0.0 2.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEH12777.1 - 1.6e-09 37.4 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEH12777.1 - 1.2e-07 31.2 0.0 2.5e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 CEH12777.1 - 0.0023 17.9 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain KTI12 PF08433.10 CEH12778.1 - 1.2e-52 179.1 0.0 2.6e-52 177.9 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CEH12778.1 - 1.1e-07 32.2 2.0 3.5e-07 30.5 0.6 2.6 2 1 0 2 2 2 1 AAA domain PCMT PF01135.19 CEH12779.1 - 1.6e-54 184.9 0.0 1.2e-39 136.3 0.0 2.2 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CEH12779.1 - 0.00026 20.8 0.2 0.00045 20.1 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH12779.1 - 0.00074 20.2 0.0 0.0014 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH12779.1 - 0.0014 19.2 0.0 0.0027 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CEH12779.1 - 0.004 17.2 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH12779.1 - 0.0099 15.7 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEH12779.1 - 0.011 15.2 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 CEH12779.1 - 0.014 14.4 0.1 0.19 10.6 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1698) MetW PF07021.12 CEH12779.1 - 0.033 13.8 0.1 0.061 12.9 0.1 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 CEH12779.1 - 0.043 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HTH_DeoR PF08220.12 CEH12779.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MTS PF05175.14 CEH12779.1 - 0.21 11.1 0.1 0.57 9.7 0.1 1.5 1 1 1 2 2 2 0 Methyltransferase small domain Prp18 PF02840.15 CEH12781.1 - 2.2e-60 202.9 0.1 5.5e-60 201.6 0.1 1.7 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 CEH12781.1 - 3.1e-08 33.0 3.6 8.4e-08 31.6 3.6 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Spore_coat_CotO PF14153.6 CEH12781.1 - 9.5 6.1 8.6 1.5 8.7 1.0 2.3 2 0 0 2 2 2 0 Spore coat protein CotO PMM PF03332.13 CEH12782.1 - 3.6e-99 331.0 0.1 5e-99 330.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase RabGAP-TBC PF00566.18 CEH12782.1 - 4.2e-23 82.1 0.0 2.9e-22 79.4 0.0 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MRPL52 PF18699.1 CEH12782.1 - 0.33 11.2 8.6 1.7 8.9 0.0 3.7 3 0 0 3 3 3 0 Mitoribosomal protein mL52 FAM176 PF14851.6 CEH12783.1 - 0.059 13.0 1.4 0.15 11.7 1.4 1.7 1 0 0 1 1 1 0 FAM176 family RGS12_us1 PF16613.5 CEH12784.1 - 0.54 10.6 7.8 5.2 7.4 0.2 3.2 3 0 0 3 3 3 0 Unstructured region of RGS12 GST_N_3 PF13417.6 CEH12785.1 - 1.1e-08 35.3 0.0 2.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEH12785.1 - 2.9e-06 27.5 0.0 7.6e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEH12785.1 - 5.1e-05 23.2 1.0 0.00049 20.1 0.9 2.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEH12785.1 - 0.0021 18.3 0.2 0.049 13.9 0.1 3.0 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEH12785.1 - 0.029 14.6 0.1 0.13 12.4 0.1 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Dor1 PF04124.12 CEH12786.1 - 5.6e-13 48.3 7.1 1.1e-12 47.3 4.1 2.4 2 0 0 2 2 2 2 Dor1-like family Rcd1 PF04078.13 CEH12787.1 - 2.8e-123 410.3 1.1 3.6e-123 409.9 1.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Scs3p PF10261.9 CEH12788.1 - 2.9e-41 141.6 0.0 5.2e-25 88.4 0.0 2.7 2 1 0 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM Hexokinase_2 PF03727.16 CEH12789.1 - 1.1e-81 273.8 0.0 1.5e-81 273.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEH12789.1 - 2.7e-67 226.6 0.0 4e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase ComR_TPR PF18710.1 CEH12789.1 - 0.12 11.9 0.8 0.2 11.2 0.3 1.7 2 0 0 2 2 2 0 ComR tetratricopeptide DUF2862 PF11061.8 CEH12789.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) DUF2834 PF11196.8 CEH12790.1 - 0.001 19.4 15.1 0.19 12.1 0.7 3.9 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) DUF5134 PF17197.4 CEH12790.1 - 0.047 13.6 4.2 0.08 12.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) Peptidase_M20 PF01546.28 CEH12794.1 - 9.8e-24 84.2 0.0 1.8e-23 83.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CEH12794.1 - 1.6e-09 37.7 0.0 3.9e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CEH12794.1 - 0.0013 18.5 0.0 0.0041 16.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 PI_PP_C PF18365.1 CEH12794.1 - 0.15 12.1 0.0 17 5.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain CRAL_TRIO PF00650.20 CEH12795.1 - 1.5e-39 135.3 0.0 2e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CEH12795.1 - 1.1e-05 25.6 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEH12795.1 - 0.0004 20.5 0.2 0.00084 19.5 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PRiA4_ORF3 PF07929.11 CEH12795.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein TRM PF02005.16 CEH12796.1 - 1.9e-110 369.6 0.0 3.6e-82 276.5 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase GTP_EFTU PF00009.27 CEH12798.1 - 1.4e-56 191.1 0.0 2.7e-56 190.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CEH12798.1 - 1.1e-33 115.5 0.7 2.4e-33 114.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 CEH12798.1 - 2.4e-30 104.5 0.0 8.6e-30 102.7 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 CEH12798.1 - 8.2e-25 86.7 0.1 1.9e-24 85.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CEH12798.1 - 4.4e-13 49.4 0.0 1.1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CEH12798.1 - 7.3e-06 25.8 0.0 2.2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Glyco_hydro_28 PF00295.17 CEH12800.1 - 2.3e-41 141.9 0.0 3.1e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 GMC_oxred_N PF00732.19 CEH12802.1 - 0.037 13.4 0.2 0.045 13.1 0.2 1.1 1 0 0 1 1 1 0 GMC oxidoreductase Leu_zip PF15294.6 CEH12803.1 - 0.026 14.1 0.6 0.037 13.5 0.6 1.1 1 0 0 1 1 1 0 Leucine zipper PspB PF06667.12 CEH12804.1 - 0.047 13.7 0.3 0.098 12.7 0.3 1.5 1 0 0 1 1 1 0 Phage shock protein B HTH_26 PF13443.6 CEH12804.1 - 0.079 13.4 0.6 0.26 11.7 0.0 2.0 2 1 1 3 3 3 0 Cro/C1-type HTH DNA-binding domain RT_RNaseH PF17917.1 CEH12806.1 - 3.4e-32 110.9 0.0 7.1e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEH12806.1 - 2e-31 108.0 0.1 4.2e-31 106.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEH12806.1 - 2.6e-16 59.8 0.1 4.9e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEH12806.1 - 1.4e-12 47.9 0.0 4.3e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEH12806.1 - 8.9e-12 44.9 0.1 3e-11 43.3 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEH12806.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger ADH_zinc_N PF00107.26 CEH12807.1 - 1.3e-08 34.9 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CEH12807.1 - 0.21 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus TP_methylase PF00590.20 CEH12808.1 - 3.4e-37 128.5 0.7 5.1e-36 124.6 0.7 2.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 CEH12808.1 - 6.1e-10 39.5 0.0 8.2e-09 35.8 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 CEH12808.1 - 1.6e-09 37.0 0.2 3.4e-09 36.0 0.2 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 CEH12808.1 - 2e-09 37.0 5.4 8.6e-08 31.7 1.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal PH PF00169.29 CEH12809.1 - 1.6e-05 25.3 0.1 5.4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 PH domain betaPIX_CC PF16523.5 CEH12809.1 - 0.063 13.1 0.5 11 5.9 0.0 2.5 1 1 1 2 2 2 0 betaPIX coiled coil CAF1A PF12253.8 CEH12809.1 - 0.089 13.0 5.7 0.28 11.4 5.7 1.9 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A AIP3 PF03915.13 CEH12809.1 - 0.13 11.4 5.0 0.24 10.4 5.0 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 Mito_carr PF00153.27 CEH12811.1 - 1.1e-62 207.9 0.2 2.9e-24 84.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glug PF07581.12 CEH12811.1 - 0.52 10.8 2.8 0.53 10.8 0.1 2.4 3 0 0 3 3 3 0 The GLUG motif DUF3292 PF11696.8 CEH12812.1 - 4.3e-11 41.9 0.1 4.3e-06 25.4 0.1 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF3292) DUF639 PF04842.12 CEH12812.1 - 0.13 11.7 0.0 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) LIP PF03583.14 CEH12814.1 - 1.4e-53 182.1 0.0 2e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 CEH12814.1 - 1.1 8.7 5.4 13 5.1 0.2 2.8 1 1 1 2 2 2 0 Prolyl oligopeptidase family HLH PF00010.26 CEH12816.1 - 7.8e-08 32.2 3.3 1.6e-07 31.2 3.3 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Selenoprotein_S PF06936.11 CEH12816.1 - 1.1 9.1 9.6 0.76 9.6 7.4 1.8 1 1 1 2 2 2 0 Selenoprotein S (SelS) zf-C2H2 PF00096.26 CEH12819.1 - 2e-06 27.9 15.2 0.00024 21.4 1.8 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEH12819.1 - 0.00099 19.4 4.0 0.00099 19.4 4.0 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEH12819.1 - 0.01 16.6 12.0 0.68 10.9 3.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger SKN1 PF03935.15 CEH12820.1 - 3.7e-190 632.6 0.7 4.4e-190 632.4 0.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 CEH12820.1 - 2.2e-05 24.0 0.3 0.0044 16.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 P16-Arc PF04699.14 CEH12826.1 - 2.9e-49 167.4 0.0 3.3e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 CEH12826.1 - 0.0028 17.9 0.0 0.0044 17.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Phage-MuB_C PF09077.11 CEH12826.1 - 0.12 12.3 0.1 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 Mu B transposition protein, C terminal Ins_P5_2-kin PF06090.12 CEH12828.1 - 9.2e-24 84.5 0.0 2.2e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase TPR_1 PF00515.28 CEH12828.1 - 1.1e-11 44.1 1.2 0.00056 19.6 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEH12828.1 - 3.5e-11 42.3 16.9 2.7e-05 23.9 0.1 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEH12828.1 - 3.7e-11 43.4 10.9 0.0005 20.5 1.2 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEH12828.1 - 2.5e-09 36.6 9.4 0.0019 18.3 0.0 6.3 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEH12828.1 - 3.6e-09 37.1 3.7 3.6e-09 37.1 3.7 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEH12828.1 - 1.5e-08 34.2 0.0 0.00026 20.6 0.0 3.5 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 CEH12828.1 - 5.3e-06 26.4 6.3 0.0018 18.5 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEH12828.1 - 6.9e-05 23.1 22.2 0.0067 16.7 0.5 6.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEH12828.1 - 0.00021 21.8 43.5 0.006 17.3 0.1 9.3 7 3 3 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEH12828.1 - 0.0045 16.9 16.0 0.27 11.4 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH12828.1 - 0.012 15.9 5.9 0.58 10.4 0.1 4.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CEH12828.1 - 0.23 11.6 20.0 0.15 12.2 2.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat SCAB-Ig PF16709.5 CEH12829.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein Pkinase PF00069.25 CEH12830.1 - 1.3e-66 224.6 0.0 4.9e-59 199.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH12830.1 - 8.9e-37 126.8 0.0 1e-32 113.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 CEH12830.1 - 1.9e-09 37.1 0.1 3.4e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CEH12830.1 - 3.4e-08 33.2 0.0 6.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEH12830.1 - 0.0045 16.0 0.2 0.0072 15.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CEH12830.1 - 0.045 13.4 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CEH12830.1 - 0.048 13.6 0.1 0.048 13.6 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEH12830.1 - 0.093 11.5 0.0 0.093 11.5 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase Rep_fac-A_3 PF08661.11 CEH12831.1 - 5.4e-24 84.6 0.0 6e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Hat1_N PF10394.9 CEH12832.1 - 3.1e-44 151.0 0.0 4.6e-24 85.5 0.0 2.5 1 1 1 2 2 2 2 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.18 CEH12832.1 - 0.0017 18.1 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_1 PF00583.25 CEH12832.1 - 0.0077 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEH12832.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ACOX PF01756.19 CEH12833.1 - 4.5e-09 36.1 0.0 9e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 CEH12833.1 - 6.2e-06 26.5 0.0 1.6e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEH12833.1 - 1.1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain TAL_effector PF03377.13 CEH12833.1 - 0.03 14.7 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 TAL effector repeat LRR19-TM PF15176.6 CEH12836.1 - 4.2 7.4 6.8 6.7 6.8 0.2 3.2 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Mitofilin PF09731.9 CEH12837.1 - 5.5e-61 207.2 21.5 5.4e-34 118.1 15.3 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein ISG65-75 PF11727.8 CEH12837.1 - 0.0064 15.8 8.5 0.0064 15.8 8.5 2.7 2 1 1 3 3 3 1 Invariant surface glycoprotein Exonuc_VII_L PF02601.15 CEH12837.1 - 0.12 11.9 9.8 0.77 9.3 3.3 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1771 PF08590.10 CEH12837.1 - 1.6 9.2 18.3 8.3 6.9 1.9 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1771) SAP PF02037.27 CEH12838.1 - 6.8e-12 44.9 1.4 1.1e-11 44.2 0.3 2.0 2 0 0 2 2 2 1 SAP domain Aminotran_5 PF00266.19 CEH12839.1 - 6.1e-06 25.4 0.0 9.1e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V XPA_C PF05181.12 CEH12840.1 - 5.9e-24 83.8 3.3 1.1e-23 83.0 3.3 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 CEH12840.1 - 1.4e-05 25.0 1.2 2.6e-05 24.2 1.2 1.4 1 0 0 1 1 1 1 XPA protein N-terminal WLM PF08325.10 CEH12841.1 - 2e-50 171.5 0.1 3.2e-50 170.9 0.1 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 CEH12841.1 - 8.7e-06 24.9 13.4 1.2e-05 24.5 3.3 3.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others SRP-alpha_N PF04086.13 CEH12841.1 - 0.017 15.1 0.4 0.017 15.1 0.4 1.6 1 1 1 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Rotamase PF00639.21 CEH12841.1 - 0.017 16.0 1.7 0.57 11.2 0.0 3.6 3 1 2 5 5 5 0 PPIC-type PPIASE domain Vps36-NZF-N PF16988.5 CEH12841.1 - 0.02 14.2 7.0 1.2 8.5 0.6 3.3 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 CEH12841.1 - 0.83 9.7 9.0 2 8.5 9.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon T3SSipB PF16535.5 CEH12841.1 - 0.97 9.9 6.0 1.2 9.6 2.6 2.4 3 0 0 3 3 3 0 Type III cell invasion protein SipB C1_2 PF03107.16 CEH12841.1 - 1.8 8.9 9.1 3.2 8.2 0.5 2.9 2 1 0 2 2 2 0 C1 domain SUV3_C PF12513.8 CEH12842.1 - 7.7e-14 51.4 0.5 2e-13 50.0 0.5 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CEH12842.1 - 1.4e-09 38.3 0.0 3.7e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 CEH12842.1 - 0.078 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 CPDase PF07823.11 CEH12843.1 - 5.1e-17 62.2 0.1 3.3e-16 59.6 0.1 1.9 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 CEH12843.1 - 3.4e-05 23.8 0.2 0.013 15.4 0.0 2.2 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 CEH12843.1 - 0.021 15.0 0.0 0.052 13.7 0.0 1.7 2 0 0 2 2 2 0 LigT like Phosphoesterase Neural_ProG_Cyt PF06567.11 CEH12843.1 - 0.053 13.8 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain 3HBOH PF10605.9 CEH12843.1 - 0.13 10.4 0.0 0.16 10.1 0.0 1.0 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) SNF2_N PF00176.23 CEH12844.1 - 1.5e-49 168.6 0.0 2.6e-49 167.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 CEH12844.1 - 1.2e-40 139.6 0.0 8.2e-40 136.9 0.0 2.1 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 CEH12844.1 - 8.5e-14 51.8 0.0 3.3e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH12844.1 - 7.4e-07 29.3 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CEH12844.1 - 7.2e-05 22.1 0.0 0.00058 19.1 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 BSP PF04450.12 CEH12846.1 - 1.4e-40 139.3 0.0 1.7e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 CEH12846.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 CEH12846.1 - 0.00037 20.8 0.1 0.00054 20.3 0.1 1.2 1 0 0 1 1 1 1 Effector protein BLM10_mid PF16507.5 CEH12847.1 - 2.7e-145 485.0 0.0 4.9e-145 484.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 CEH12847.1 - 8.3e-24 83.3 0.1 1.2e-22 79.6 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 CEH12847.1 - 3.7e-05 23.6 1.1 0.012 15.8 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.23 CEH12847.1 - 0.0003 20.7 1.6 0.0016 18.4 0.0 3.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CEH12847.1 - 0.00095 19.5 11.8 0.0064 16.9 0.1 5.3 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 CEH12847.1 - 0.0078 16.7 0.1 0.19 12.3 0.1 3.5 2 0 0 2 2 2 1 HEAT-like repeat BLM10_N PF16547.5 CEH12847.1 - 0.053 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Cnd1 PF12717.7 CEH12847.1 - 0.16 12.0 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 VWA_2 PF13519.6 CEH12848.1 - 4.6e-23 81.9 0.1 1.3e-22 80.5 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 CEH12848.1 - 1.4e-09 38.4 0.0 2.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 CEH12848.1 - 3.4e-07 29.7 4.8 0.00028 20.6 2.5 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif Ssl1 PF04056.14 CEH12848.1 - 2.2e-06 27.7 0.0 3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like YjeF_N PF03853.15 CEH12848.1 - 0.05 13.5 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus Neugrin PF06413.11 CEH12848.1 - 0.17 11.9 1.6 0.61 10.1 0.1 2.1 2 0 0 2 2 2 0 Neugrin STE3 PF02076.15 CEH12850.1 - 3.8e-76 256.1 11.2 4.7e-76 255.8 11.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor MARVEL PF01284.23 CEH12850.1 - 0.53 10.3 10.8 0.032 14.3 3.9 2.6 2 1 1 3 3 3 0 Membrane-associating domain Pheromone PF08015.11 CEH12851.1 - 0.045 14.8 0.0 3.9 8.6 0.0 2.1 2 0 0 2 2 2 0 Fungal mating-type pheromone STE3 PF02076.15 CEH12852.1 - 1.2e-67 228.2 6.5 1.3e-67 228.0 6.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.12 CEH12852.1 - 0.067 13.0 0.2 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Orf78 PF06024.12 CEH12852.1 - 0.23 11.8 1.1 1.7 9.0 0.3 2.2 2 0 0 2 2 2 0 Orf78 (ac78) IKKbetaNEMObind PF12179.8 CEH12853.1 - 0.0071 16.4 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 I-kappa-kinase-beta NEMO binding domain Elong_Iki1 PF10483.9 CEH12853.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Elongator subunit Iki1 RNase_H2-Ydr279 PF09468.10 CEH12854.1 - 8e-11 42.4 0.8 1.3e-10 41.7 0.8 1.4 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 CEH12854.1 - 1.1e-10 41.6 0.0 4.8e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Ydr279p protein triple barrel domain NmrA PF05368.13 CEH12855.1 - 5.7e-18 65.3 0.0 7.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Ribosomal_S19 PF00203.21 CEH12858.1 - 2e-26 91.7 0.1 2.1e-26 91.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_S13_N PF08069.12 CEH12860.1 - 1.6e-25 88.9 0.1 3.1e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CEH12860.1 - 1.1e-13 51.2 0.1 1.7e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 HTH_32 PF13565.6 CEH12860.1 - 0.021 15.4 4.2 0.11 13.1 4.2 2.1 1 1 0 1 1 1 0 Homeodomain-like domain PAX PF00292.18 CEH12860.1 - 0.044 13.7 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain Ribosomal_S6e PF01092.19 CEH12861.1 - 6.8e-51 171.5 0.1 1.5e-50 170.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Exo_endo_phos PF03372.23 CEH12862.1 - 3e-17 62.9 0.2 4.7e-17 62.3 0.2 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Forkhead PF00250.18 CEH12863.1 - 1.2e-10 41.5 0.2 2.2e-10 40.7 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain Lipase_3 PF01764.25 CEH12865.1 - 3.5e-16 59.3 0.0 1e-15 57.9 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) RRM_1 PF00076.22 CEH12866.1 - 2.2e-15 56.2 0.0 3.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nuc_sug_transp PF04142.15 CEH12867.1 - 7.6e-06 25.3 0.1 1.4e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CEH12867.1 - 0.00026 21.2 25.5 0.0082 16.3 5.9 3.4 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 CEH12867.1 - 0.0015 17.9 2.6 0.0015 17.9 2.6 1.8 1 1 1 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 CEH12867.1 - 5.3 6.2 12.4 46 3.1 12.4 2.2 1 1 0 1 1 1 0 UAA transporter family Chorismate_bind PF00425.18 CEH12868.1 - 4.5e-78 262.4 0.0 6.8e-78 261.8 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 CEH12868.1 - 1.4e-26 93.4 0.0 5.3e-26 91.5 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Protocadherin PF08374.11 CEH12871.1 - 0.045 13.7 0.1 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Protocadherin DUF4064 PF13273.6 CEH12871.1 - 0.066 13.5 7.9 8.1 6.8 2.3 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF4064) Tetraspanin PF00335.20 CEH12871.1 - 0.18 11.5 12.7 1 9.0 12.6 2.0 1 1 0 1 1 1 0 Tetraspanin family ICE2 PF08426.10 CEH12871.1 - 0.53 9.3 4.1 0.14 11.2 1.1 1.6 2 0 0 2 2 2 0 ICE2 FMO-like PF00743.19 CEH12873.1 - 1.4e-11 43.5 0.0 1.1e-05 24.1 0.0 2.3 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CEH12873.1 - 1.9e-06 28.0 0.0 5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CEH12873.1 - 1.5e-05 24.4 0.0 0.13 11.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEH12873.1 - 0.00045 19.5 0.0 0.0055 15.9 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CEH12873.1 - 0.00075 18.8 0.3 1.6 7.9 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEH12873.1 - 0.012 15.2 0.3 0.11 12.0 0.2 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEH12873.1 - 0.12 12.4 0.0 21 5.1 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 CEH12873.1 - 0.13 11.3 0.0 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GST_C PF00043.25 CEH12874.1 - 4.5e-11 42.8 0.0 1.4e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CEH12874.1 - 8.5e-10 38.8 0.1 3.4e-09 36.9 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CEH12874.1 - 6.6e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEH12874.1 - 2.2e-07 30.8 0.0 5.9e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CEH12874.1 - 2.8e-07 30.7 0.0 4.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CEH12874.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.22 CEH12876.1 - 8.1e-24 83.2 0.0 1.2e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 CEH12876.1 - 3.1e-09 36.0 0.0 0.0071 16.0 0.0 3.6 3 0 0 3 3 3 3 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 CEH12876.1 - 0.0078 16.1 0.0 4.4 7.2 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RCR PF12273.8 CEH12878.1 - 0.37 11.5 2.8 0.2 12.3 1.0 1.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Acyltransferase PF01553.21 CEH12879.1 - 1.2e-22 80.0 0.0 2.7e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CEH12879.1 - 5.3e-05 23.2 0.7 0.00015 21.8 0.2 1.9 2 0 0 2 2 2 1 Acyltransferase C-terminus Mid1 PF12929.7 CEH12882.1 - 5.8e-57 193.8 0.1 7.7e-57 193.4 0.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 CEH12882.1 - 0.0053 17.4 0.5 0.12 13.0 0.0 2.5 2 1 0 2 2 2 1 Fz domain fn3 PF00041.21 CEH12882.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain DDOST_48kD PF03345.14 CEH12884.1 - 2.5e-76 257.2 0.0 3.5e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DHHC PF01529.20 CEH12884.1 - 5.6e-08 33.0 0.1 5.6e-08 33.0 0.1 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-Nse PF11789.8 CEH12885.1 - 3.2e-18 65.3 0.1 5.3e-18 64.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 CEH12885.1 - 4e-08 33.3 0.0 8.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.6 CEH12885.1 - 4.6e-05 23.4 0.3 9e-05 22.4 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEH12885.1 - 0.017 14.9 0.8 0.031 14.1 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 CEH12885.1 - 0.045 13.5 1.2 0.099 12.4 1.2 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-ANAPC11 PF12861.7 CEH12885.1 - 0.079 13.0 0.1 0.22 11.6 0.2 1.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CEH12885.1 - 0.1 12.5 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 CEH12885.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 CEH12885.1 - 0.2 12.0 0.6 0.35 11.2 0.6 1.5 1 0 0 1 1 1 0 Ring finger domain Prefoldin PF02996.17 CEH12886.1 - 1.2e-26 93.0 0.5 1.6e-26 92.5 0.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit Sec1 PF00995.23 CEH12886.1 - 0.0023 17.2 0.9 0.0031 16.8 0.9 1.1 1 0 0 1 1 1 1 Sec1 family CNTF PF01110.17 CEH12886.1 - 0.0025 17.2 0.9 0.0044 16.4 0.9 1.4 1 0 0 1 1 1 1 Ciliary neurotrophic factor Ribosomal_L28e PF01778.17 CEH12887.1 - 5.9e-17 62.5 0.2 8.6e-17 61.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family ssDNA_TraI_N PF18272.1 CEH12887.1 - 0.076 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain Pkinase PF00069.25 CEH12888.1 - 3e-36 125.1 0.0 7.2e-35 120.6 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH12888.1 - 2.9e-21 75.9 0.0 7.2e-21 74.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH12888.1 - 0.0034 16.7 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEH12888.1 - 0.4 10.6 6.0 0.95 9.3 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF2203 PF09969.9 CEH12888.1 - 1.6 9.4 4.2 3.3 8.4 4.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Type_III_YscG PF09477.10 CEH12889.1 - 0.098 12.7 0.4 0.16 12.1 0.4 1.5 1 1 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) PAC4 PF16093.5 CEH12891.1 - 0.00012 22.2 1.1 0.001 19.2 0.1 2.3 2 0 0 2 2 2 1 Proteasome assembly chaperone 4 DUF3035 PF11233.8 CEH12891.1 - 0.19 12.0 4.8 0.36 11.1 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) Vps26 PF03643.15 CEH12892.1 - 2e-129 430.5 1.8 2.2e-129 430.3 1.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CEH12892.1 - 0.039 14.0 0.3 1.7 8.7 0.0 3.0 2 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Ras PF00071.22 CEH12894.1 - 8.8e-53 178.2 0.0 1e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH12894.1 - 1.9e-22 79.7 0.0 2.9e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH12894.1 - 8.3e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEH12894.1 - 0.02 14.8 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CEH12894.1 - 0.021 15.2 0.0 0.26 11.7 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 CEH12894.1 - 0.17 11.7 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CAF1A PF12253.8 CEH12896.1 - 4.4e-22 78.0 1.9 4.4e-22 78.0 1.9 3.1 2 1 1 3 3 3 1 Chromatin assembly factor 1 subunit A AA_kinase PF00696.28 CEH12897.1 - 1e-41 143.1 0.3 1.9e-41 142.2 0.3 1.5 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 CEH12897.1 - 1.3e-10 41.1 1.0 3.8e-05 23.6 0.0 3.1 3 0 0 3 3 3 2 PUA domain GATase_5 PF13507.6 CEH12898.1 - 4.2e-95 317.8 0.0 5.9e-95 317.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CEH12898.1 - 1.3e-40 139.1 2.0 1e-26 93.9 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 CEH12898.1 - 8.2e-23 80.7 0.0 7.2e-22 77.7 0.0 2.4 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain TruB_C PF09142.11 CEH12898.1 - 0.026 14.3 0.0 0.11 12.3 0.0 2.1 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal AIRS PF00586.24 CEH12898.1 - 0.18 12.5 4.7 1.5 9.5 0.0 3.9 3 1 1 4 4 4 0 AIR synthase related protein, N-terminal domain DUF1490 PF07371.12 CEH12898.1 - 0.62 10.2 6.5 2.9 8.1 1.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) Peroxidase_2 PF01328.17 CEH12899.1 - 1e-28 101.1 0.0 3e-24 86.6 0.0 2.1 2 0 0 2 2 2 2 Peroxidase, family 2 PrmC_N PF17827.1 CEH12901.1 - 0.13 12.8 0.3 8.3 7.1 0.1 2.4 2 0 0 2 2 2 0 PrmC N-terminal domain DUF659 PF04937.15 CEH12902.1 - 9.7e-06 25.5 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CEH12902.1 - 0.06 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF3072 PF11272.8 CEH12902.1 - 0.15 12.0 0.9 2.4 8.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3072) DUF659 PF04937.15 CEH12904.1 - 9.7e-06 25.5 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CEH12904.1 - 0.06 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF3072 PF11272.8 CEH12904.1 - 0.15 12.0 0.9 2.4 8.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3072) RINGv PF12906.7 CEH12906.1 - 0.008 16.3 0.3 0.014 15.6 0.3 1.4 1 0 0 1 1 1 1 RING-variant domain DUF308 PF03729.13 CEH12906.1 - 0.31 11.4 10.6 0.5 10.7 0.6 3.3 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF2157 PF09925.9 CEH12906.1 - 0.33 10.7 2.0 1.1 9.0 0.1 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) Rhomboid PF01694.22 CEH12907.1 - 1.9e-10 40.9 18.5 2.8e-09 37.1 18.5 2.3 1 1 0 1 1 1 1 Rhomboid family Bax1-I PF01027.20 CEH12907.1 - 9 6.1 14.4 3.2 7.5 8.4 2.5 2 1 1 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 Ribonuclease PF00545.20 CEH12908.1 - 6.3e-05 23.6 0.5 8.7e-05 23.2 0.5 1.2 1 0 0 1 1 1 1 ribonuclease SurA_N_3 PF13624.6 CEH12908.1 - 0.032 14.0 0.0 0.041 13.7 0.0 1.1 1 0 0 1 1 1 0 SurA N-terminal domain Ras PF00071.22 CEH12909.1 - 2.3e-53 180.1 0.0 2.7e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH12909.1 - 4e-19 69.0 0.0 5.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH12909.1 - 7.4e-07 28.8 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEH12909.1 - 0.08 12.5 0.1 0.68 9.4 0.0 2.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Brr6_like_C_C PF10104.9 CEH12910.1 - 1.3e-28 99.4 0.0 1.8e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain XRCC4 PF06632.12 CEH12910.1 - 0.073 11.9 0.5 0.11 11.4 0.5 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 MFS_1 PF07690.16 CEH12912.1 - 8e-23 80.9 34.4 1.3e-22 80.2 34.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CEH12912.1 - 0.02 13.3 3.0 0.032 12.7 3.0 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Baculo_helicase PF04735.12 CEH12912.1 - 0.31 8.5 0.0 0.42 8.1 0.0 1.0 1 0 0 1 1 1 0 Baculovirus DNA helicase DUF2070 PF09843.9 CEH12912.1 - 7.9 4.6 7.0 14 3.8 7.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) WSC PF01822.19 CEH12913.1 - 7.9e-43 144.5 38.3 1.7e-15 56.9 12.7 3.3 3 0 0 3 3 3 3 WSC domain RNA_pol_N PF01194.17 CEH12914.1 - 2.9e-31 107.5 0.4 3.4e-31 107.3 0.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit ApoO PF09769.9 CEH12915.1 - 1.7e-27 95.9 0.4 3.3e-27 95.0 0.0 1.6 2 0 0 2 2 2 1 Apolipoprotein O Methyltransf_10 PF05971.12 CEH12916.1 - 1.7e-55 188.5 0.1 6.3e-38 130.8 0.0 2.2 1 1 0 2 2 2 2 RNA methyltransferase PGA2 PF07543.12 CEH12916.1 - 0.18 11.8 0.3 0.34 10.9 0.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 HEAT PF02985.22 CEH12917.1 - 6.7e-17 60.1 14.1 0.00033 20.7 0.0 10.3 11 1 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 CEH12917.1 - 1.7e-16 60.3 13.4 8.4e-08 32.6 0.0 7.7 7 1 1 8 8 8 3 HEAT-like repeat Arm PF00514.23 CEH12917.1 - 2.3e-06 27.5 9.9 0.0022 18.0 0.0 5.7 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 CEH12917.1 - 4.7e-06 26.4 0.1 0.00022 21.1 0.0 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CEH12917.1 - 2.1e-05 24.8 17.6 0.016 15.6 0.0 7.4 4 2 4 9 9 8 2 HEAT repeats Cnd1 PF12717.7 CEH12917.1 - 0.0014 18.7 0.1 0.23 11.5 0.0 4.1 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CEH12917.1 - 0.0052 15.4 0.1 0.19 10.3 0.0 2.5 2 0 0 2 2 2 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 CEH12917.1 - 0.033 14.8 0.5 20 5.9 0.5 4.7 3 2 2 5 5 5 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CEH12917.1 - 0.043 13.4 0.0 4.4 6.8 0.0 3.5 3 0 0 3 3 3 0 CLASP N terminal V-ATPase_H_C PF11698.8 CEH12917.1 - 0.21 11.7 0.1 0.65 10.1 0.1 1.9 1 0 0 1 1 1 0 V-ATPase subunit H BPL_LplA_LipB PF03099.19 CEH12919.1 - 0.0016 18.4 0.0 0.0052 16.7 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family RINGv PF12906.7 CEH12920.1 - 2e-05 24.6 10.2 3.7e-05 23.8 10.2 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.6 CEH12920.1 - 0.012 15.4 3.1 0.025 14.4 3.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 CEH12920.1 - 0.042 14.2 6.1 0.079 13.3 6.1 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 CEH12920.1 - 0.39 10.9 4.0 0.74 10.0 4.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CEH12920.1 - 0.93 9.2 3.6 2 8.1 3.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RNA_polI_A34 PF08208.11 CEH12921.1 - 7.6e-11 42.5 6.9 1.2e-09 38.6 6.9 2.3 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RRM_1 PF00076.22 CEH12922.1 - 7.2e-12 45.0 0.0 1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NIF3 PF01784.18 CEH12924.1 - 1.2e-52 179.0 0.0 1.6e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) HLH PF00010.26 CEH12925.1 - 6.7e-09 35.6 0.9 1.2e-08 34.8 0.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TolA_bind_tri PF16331.5 CEH12925.1 - 0.044 13.9 0.5 0.044 13.9 0.5 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 CEH12925.1 - 5 7.2 12.9 1.1 9.3 2.1 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein eIF-5a PF01287.20 CEH12926.1 - 1.9e-26 91.9 0.1 2.6e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold TgMIC1 PF11476.8 CEH12926.1 - 0.0022 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 Toxoplasma gondii micronemal protein 1 TgMIC1 EFP_N PF08207.12 CEH12926.1 - 0.0053 16.8 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Adap_comp_sub PF00928.21 CEH12927.1 - 2.4e-16 59.9 0.0 3.6e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CEH12927.1 - 1.4e-07 31.5 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LSM PF01423.22 CEH12928.1 - 4.3e-19 68.0 0.0 5.2e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 CEH12928.1 - 5.5 7.6 13.7 9.3 6.9 13.7 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 FA_desaturase PF00487.24 CEH12929.1 - 2.3e-25 89.9 22.0 4.6e-25 88.9 22.0 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CEH12929.1 - 9.4e-10 38.5 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tetraspanin PF00335.20 CEH12931.1 - 0.0087 15.8 0.8 0.13 11.9 0.2 2.1 2 0 0 2 2 2 1 Tetraspanin family TctB PF07331.11 CEH12931.1 - 0.034 14.4 5.3 1.1 9.6 3.6 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family PI3_PI4_kinase PF00454.27 CEH12932.1 - 1.3e-22 80.8 0.0 3.9e-22 79.3 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SurE PF01975.17 CEH12934.1 - 5.5e-13 49.1 0.0 8.5e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Imm_superinfect PF14373.6 CEH12934.1 - 0.14 12.1 0.3 0.44 10.5 0.2 1.8 2 0 0 2 2 2 0 Superinfection immunity protein RED_N PF07808.13 CEH12935.1 - 6.8e-05 22.6 1.8 6.8e-05 22.6 1.8 2.1 2 0 0 2 2 2 1 RED-like protein N-terminal region DUF1179 PF06678.11 CEH12935.1 - 9.6 6.2 10.4 4.8 7.2 3.1 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1179) Mus7 PF09462.10 CEH12936.1 - 2.7e-107 360.2 0.8 4e-107 359.6 0.8 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Ribonucleas_3_2 PF11469.8 CEH12936.1 - 0.092 13.2 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease III F-box-like PF12937.7 CEH12938.1 - 8.7e-06 25.5 1.6 1.1e-05 25.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEH12938.1 - 0.076 12.9 0.1 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 F-box domain DHBP_synthase PF00926.19 CEH12939.1 - 1.6e-67 226.8 0.1 1.8e-67 226.6 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase SNARE_assoc PF09335.11 CEH12940.1 - 3.8e-05 24.1 0.2 9e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein CbiM PF01891.16 CEH12940.1 - 0.31 10.8 6.2 0.47 10.3 6.2 1.2 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Glyco_hydro_20 PF00728.22 CEH12941.1 - 8.5e-74 249.0 0.0 1.2e-73 248.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CEH12941.1 - 1.1e-07 32.5 5.1 9.3e-07 29.6 5.1 2.4 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CEH12941.1 - 0.0099 16.7 0.1 0.039 14.7 0.1 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF348 PF03990.14 CEH12941.1 - 0.1 12.3 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain Herpes_glycoH_C PF17488.2 CEH12943.1 - 0.1 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain Tim17 PF02466.19 CEH12944.1 - 2e-28 98.9 6.0 2.9e-28 98.5 6.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ribosom_S12_S23 PF00164.25 CEH12945.1 - 1.6e-35 121.1 0.2 2.5e-35 120.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L14 PF00238.19 CEH12946.1 - 6.4e-36 123.1 0.1 7.2e-36 122.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e KH_8 PF17903.1 CEH12947.1 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CEH12947.1 - 0.0013 18.5 0.3 0.0029 17.4 0.3 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 CEH12947.1 - 0.096 12.6 0.1 9 6.3 0.0 2.4 2 0 0 2 2 2 0 KH domain APG5 PF04106.12 CEH12948.1 - 1.2e-49 169.0 0.0 1.4e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Aldo_ket_red PF00248.21 CEH12951.1 - 2.6e-17 62.9 0.0 1.3e-08 34.4 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Myotub-related PF06602.14 CEH12953.1 - 6.3e-141 469.4 0.0 8.6e-141 468.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Vps36_ESCRT-II PF11605.8 CEH12953.1 - 0.061 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Y_phosphatase PF00102.27 CEH12953.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CEH12953.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DPBB_1 PF03330.18 CEH12954.1 - 2.7e-05 24.4 0.0 6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase AbiEi_3 PF11459.8 CEH12954.1 - 0.25 11.0 0.9 0.42 10.3 0.9 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system RhlB PF12300.8 CEH12954.1 - 1.7 8.8 15.1 3.5 7.7 9.5 2.3 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB BcrAD_BadFG PF01869.20 CEH12955.1 - 2.2e-15 56.9 0.2 1.2e-14 54.4 0.2 2.1 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family TRAUB PF08164.12 CEH12956.1 - 2.3e-22 79.3 0.0 7.2e-22 77.7 0.0 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 CEH12956.1 - 5.7e-11 43.3 0.2 1.6e-10 41.8 0.2 1.8 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor F_bP_aldolase PF01116.20 CEH12957.1 - 5.9e-72 242.5 0.0 7.1e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PEN-2 PF10251.9 CEH12959.1 - 0.59 10.6 7.0 2.1 8.8 1.8 2.7 1 1 1 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Methyltransf_2 PF00891.18 CEH12960.1 - 1.5e-22 80.0 0.1 8.2e-21 74.3 0.1 2.2 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 CEH12960.1 - 0.052 14.3 0.0 0.29 11.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DUF5644 PF18712.1 CEH12960.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5644) MA3 PF02847.17 CEH12961.1 - 1.2e-29 102.5 0.1 2.7e-29 101.5 0.1 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 CEH12961.1 - 2.5e-13 50.2 0.5 9.6e-13 48.3 0.0 2.1 2 1 0 2 2 2 1 MIF4G domain DEAD PF00270.29 CEH12962.1 - 2.9e-39 134.6 0.0 1.7e-38 132.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH12962.1 - 6.4e-33 113.4 0.1 2.2e-29 102.0 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 CEH12962.1 - 1.1e-06 28.7 0.0 2.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CEH12962.1 - 0.074 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain PAP2_3 PF14378.6 CEH12963.1 - 1.4e-20 73.8 18.2 3.1e-15 56.4 2.4 2.8 2 1 1 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 CEH12963.1 - 3.1e-07 30.2 3.8 8.3e-07 28.8 3.2 2.1 1 1 0 1 1 1 1 PAP2 superfamily Sec10 PF07393.11 CEH12964.1 - 2.7e-235 783.1 0.0 3.3e-235 782.8 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF1759 PF03564.15 CEH12964.1 - 0.19 11.6 0.1 0.41 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Drf_GBD PF06371.13 CEH12965.1 - 9e-07 28.6 0.0 8.2e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain PEMT PF04191.13 CEH12966.1 - 2e-31 108.5 5.6 2e-31 108.5 5.6 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase Cyanate_lyase PF02560.14 CEH12967.1 - 2.6e-33 113.7 0.0 3.9e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 CEH12967.1 - 0.00066 20.0 0.0 0.00092 19.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Asp PF00026.23 CEH12968.1 - 6.5e-40 137.5 4.4 8e-39 133.9 4.4 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CEH12968.1 - 0.0072 16.9 2.4 0.21 12.2 0.4 2.6 2 0 0 2 2 2 1 Aspartyl protease DUF4148 PF13663.6 CEH12968.1 - 0.1 12.8 1.4 0.2 11.8 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) ATP-synt_ab_C PF00306.27 CEH12969.1 - 0.07 13.5 0.6 0.16 12.3 0.6 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain Med9 PF07544.13 CEH12969.1 - 0.11 12.6 4.9 1.4 9.0 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3410 PF11890.8 CEH12969.1 - 0.13 12.1 0.2 0.3 10.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) GAS PF13851.6 CEH12969.1 - 0.88 8.9 15.5 1.6 8.1 6.0 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 CEH12969.1 - 2.2 8.3 20.8 0.19 11.8 3.3 2.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion KLRAQ PF10205.9 CEH12969.1 - 5.5 7.3 12.6 0.41 10.9 1.5 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.9 CEH12969.1 - 7 5.6 14.8 0.19 10.8 6.4 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 CEH12969.1 - 8.3 6.4 22.2 8.2 6.5 3.3 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 2OG-FeII_Oxy_2 PF13532.6 CEH12970.1 - 7.2e-09 36.1 0.0 2.1e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 CEH12971.1 - 1.3e-22 80.0 0.0 1.7e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CEH12971.1 - 6.7e-11 41.9 0.9 1.3e-10 41.0 0.9 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding PF00501.28 CEH12972.1 - 3.1e-17 62.3 0.0 4.5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEH12972.1 - 0.041 14.9 0.2 0.093 13.7 0.2 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain gpW PF02831.15 CEH12973.1 - 0.074 13.0 0.6 0.19 11.6 0.2 1.9 2 0 0 2 2 2 0 gpW ICE2 PF08426.10 CEH12974.1 - 4e-57 194.2 10.0 1.3e-32 113.5 0.2 2.0 2 0 0 2 2 2 2 ICE2 Hydrolase_4 PF12146.8 CEH12975.1 - 2.6e-07 30.2 0.0 0.00028 20.2 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH12975.1 - 1.5e-06 28.1 0.1 9.1e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold His_Phos_2 PF00328.22 CEH12980.1 - 3.6e-15 56.2 0.0 5.3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) G-patch PF01585.23 CEH12981.1 - 6.6e-12 45.1 1.8 1.3e-11 44.2 1.8 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CEH12981.1 - 0.00013 22.0 0.2 0.00038 20.5 0.2 1.8 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 CEH12981.1 - 0.0029 17.8 0.6 0.0045 17.2 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEH12981.1 - 0.018 15.4 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CEH12981.1 - 0.11 13.1 0.5 0.19 12.2 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF4778 PF16008.5 CEH12981.1 - 0.86 9.6 4.2 1.6 8.7 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Myb_DNA-bind_6 PF13921.6 CEH12982.1 - 4.1e-06 26.9 0.1 7.6e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CEH12982.1 - 0.00071 19.7 0.2 0.0028 17.8 0.2 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CEH12983.1 - 1.6e-06 28.2 0.1 2.5e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH12983.1 - 0.0045 17.2 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CEH12984.1 - 0.00021 21.4 0.0 0.00059 20.0 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain RR_TM4-6 PF06459.12 CEH12984.1 - 0.0016 18.3 0.6 0.0022 17.8 0.6 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Myb_DNA-bind_6 PF13921.6 CEH12984.1 - 0.0035 17.6 0.1 0.01 16.1 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4746 PF15928.5 CEH12984.1 - 0.094 12.1 3.6 0.12 11.8 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 CEH12984.1 - 0.13 12.1 4.2 0.15 11.8 4.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myb_DNA-binding PF00249.31 CEH12985.1 - 0.00096 19.3 0.2 0.0023 18.1 0.2 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH12985.1 - 0.11 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ndc1_Nup PF09531.10 CEH12985.1 - 0.24 10.1 5.3 0.25 10.0 5.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.13 CEH12985.1 - 0.28 11.1 13.2 0.32 10.9 13.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.9 CEH12985.1 - 0.57 8.7 7.3 0.65 8.5 7.3 1.0 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CEH12985.1 - 2.1 5.4 8.3 2.4 5.2 8.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TMEM247 PF15444.6 CEH12985.1 - 3.1 7.8 10.1 4.2 7.4 9.8 1.3 1 1 0 1 1 1 0 Transmembrane protein 247 Myb_DNA-binding PF00249.31 CEH12986.1 - 0.00046 20.3 0.2 0.0011 19.1 0.2 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH12986.1 - 0.032 14.5 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ndc1_Nup PF09531.10 CEH12986.1 - 0.11 11.1 4.7 0.12 11.0 4.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 CEH12986.1 - 0.66 8.5 5.9 0.74 8.3 5.9 1.0 1 0 0 1 1 1 0 Macoilin family TMEM247 PF15444.6 CEH12986.1 - 9.5 6.2 9.8 14 5.6 9.5 1.4 1 1 0 1 1 1 0 Transmembrane protein 247 TruB_N PF01509.18 CEH12987.1 - 6.3e-47 159.7 0.0 2e-38 132.1 0.0 2.1 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) DUF4429 PF14472.6 CEH12987.1 - 0.12 13.0 0.7 21 5.8 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4429) FRG PF08867.11 CEH12989.1 - 0.063 14.2 0.0 0.087 13.8 0.0 1.3 1 0 0 1 1 1 0 FRG domain Hydrolase_6 PF13344.6 CEH12992.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 CEH12993.1 - 2.9e-15 56.0 0.0 5.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5536 PF17688.1 CEH12993.1 - 0.19 11.6 2.7 0.47 10.3 2.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5536) Thi4 PF01946.17 CEH12995.1 - 2.6e-96 321.4 0.2 4.3e-96 320.7 0.0 1.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 CEH12995.1 - 7.9e-10 38.8 3.6 1.6e-07 31.3 1.8 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEH12995.1 - 2.4e-06 27.7 1.4 6.1e-06 26.4 1.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CEH12995.1 - 1.2e-05 24.6 0.6 3.1e-05 23.2 0.6 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 CEH12995.1 - 1.3e-05 25.2 2.0 0.00061 19.8 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CEH12995.1 - 3.3e-05 23.3 0.1 4.3e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEH12995.1 - 0.00012 21.3 1.7 0.00098 18.3 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 CEH12995.1 - 0.00036 19.3 0.3 0.00067 18.5 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 CEH12995.1 - 0.013 14.9 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CEH12995.1 - 0.014 14.3 0.2 0.021 13.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 CEH12995.1 - 0.031 13.5 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEH12995.1 - 0.088 11.9 0.1 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Abhydrolase_3 PF07859.13 CEH12996.1 - 3.6e-30 105.4 0.0 2.9e-22 79.6 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEH12996.1 - 6.1e-08 31.9 0.0 1.7e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CEH12996.1 - 0.043 13.3 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Mak10 PF04112.13 CEH12997.1 - 2.3e-43 147.6 0.0 3.9e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase AlaDh_PNT_N PF05222.15 CEH12998.1 - 2e-27 96.1 0.0 6.9e-27 94.4 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF4618 PF15397.6 CEH12999.1 - 0.0075 15.7 8.3 0.1 12.0 2.8 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) WHIM1 PF15612.6 CEH12999.1 - 0.37 10.4 5.4 4.6 6.9 0.2 2.9 3 0 0 3 3 3 0 WSTF, HB1, Itc1p, MBD9 motif 1 OmpH PF03938.14 CEH12999.1 - 1.2 9.5 9.6 7.6 6.9 2.9 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CENP-H PF05837.12 CEH12999.1 - 1.2 9.6 14.9 6.5 7.2 6.0 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) SRC-1 PF08832.10 CEH12999.1 - 6.2 8.0 6.1 3 9.0 0.1 3.3 2 1 2 4 4 4 0 Steroid receptor coactivator DUF5437 PF17505.2 CEH12999.1 - 6.8 6.8 6.5 8.2 6.5 0.1 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5437) LZ_Tnp_IS66 PF13007.7 CEH13000.1 - 0.011 16.5 0.4 0.015 16.0 0.4 1.2 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain VHS PF00790.19 CEH13003.1 - 9.7e-15 54.6 0.0 1.6e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 VHS domain YdfA_immunity PF12127.8 CEH13003.1 - 0.17 10.9 2.5 0.31 10.1 2.5 1.3 1 0 0 1 1 1 0 SigmaW regulon antibacterial Ifi-6-16 PF06140.13 CEH13004.1 - 1.4e-12 47.3 6.6 8.2e-06 25.6 1.0 2.4 2 0 0 2 2 2 2 Interferon-induced 6-16 family Ntox47 PF15540.6 CEH13004.1 - 0.00044 20.5 0.4 0.27 11.5 0.0 2.6 1 1 2 3 3 3 2 Bacterial toxin 47 EspA PF03433.13 CEH13004.1 - 0.01 15.7 2.0 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 EspA-like secreted protein TMP_2 PF06791.13 CEH13004.1 - 0.017 14.8 1.4 3.6 7.2 0.1 2.2 2 0 0 2 2 2 0 Prophage tail length tape measure protein TAL_effector PF03377.13 CEH13004.1 - 0.063 13.6 0.0 7.2 7.0 0.0 2.4 2 0 0 2 2 2 0 TAL effector repeat DUF934 PF06073.12 CEH13004.1 - 0.16 11.9 0.1 8.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF934) RNA_pol PF00940.19 CEH13005.1 - 1.5e-203 676.2 0.3 1.3e-158 528.2 0.0 2.5 2 1 1 3 3 3 2 DNA-dependent RNA polymerase RPOL_N PF14700.6 CEH13005.1 - 2.2e-85 287.1 4.3 4.6e-85 286.0 4.3 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 CEH13005.1 - 0.0001 22.4 0.0 0.07 13.3 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family DUF2564 PF10819.8 CEH13005.1 - 0.081 13.3 0.9 0.31 11.4 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) PPR PF01535.20 CEH13005.1 - 0.12 12.7 0.3 3.6 8.0 0.0 3.0 3 0 0 3 3 3 0 PPR repeat CTP_transf_1 PF01148.20 CEH13006.1 - 8.3e-67 225.7 18.7 8.5e-62 209.3 9.8 2.1 2 0 0 2 2 2 2 Cytidylyltransferase family OAD_gamma PF04277.13 CEH13006.1 - 0.61 10.7 0.0 0.61 10.7 0.0 4.5 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain SRP54 PF00448.22 CEH13007.1 - 9.4e-75 250.6 0.3 1.5e-74 249.9 0.3 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CEH13007.1 - 9.8e-31 106.3 0.7 9.8e-31 106.3 0.7 3.6 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 CEH13007.1 - 2.9e-14 53.1 0.4 2.9e-14 53.1 0.4 1.8 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CEH13007.1 - 5.4e-05 22.8 1.0 0.0013 18.3 1.0 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CEH13007.1 - 7.7e-05 22.9 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CEH13007.1 - 0.0002 20.4 2.4 0.00063 18.8 0.6 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 CEH13007.1 - 0.0027 17.6 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 CEH13007.1 - 0.003 17.6 0.0 0.0081 16.2 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 CEH13007.1 - 0.0076 16.0 0.2 0.026 14.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEH13007.1 - 0.0088 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 CEH13007.1 - 0.03 13.7 0.2 1.2 8.6 0.1 2.6 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit APS_kinase PF01583.20 CEH13007.1 - 0.065 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 CEH13007.1 - 0.085 12.6 0.2 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein VirE PF05272.11 CEH13007.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E DUF3052 PF11253.8 CEH13007.1 - 0.17 11.8 0.0 0.54 10.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) NTPase_1 PF03266.15 CEH13007.1 - 0.54 10.1 2.1 1.4 8.8 0.1 2.5 3 0 0 3 3 3 0 NTPase Pan3_PK PF18101.1 CEH13008.1 - 1.8e-63 212.6 0.0 2.1e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Zn_clus PF00172.18 CEH13010.1 - 4.9e-05 23.4 6.9 0.0001 22.3 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CxC1 PF18802.1 CEH13010.1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases HALZ PF02183.18 CEH13010.1 - 0.39 11.0 2.8 0.2 11.9 0.5 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Sugar_tr PF00083.24 CEH13012.1 - 9.4e-31 107.1 24.7 5e-23 81.7 6.9 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 CEH13012.1 - 1.1e-25 90.4 34.4 1.1e-25 90.4 34.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 CEH13012.1 - 1.3e-05 24.7 2.9 1.3e-05 24.7 2.9 2.4 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Phage_holin_2_4 PF16082.5 CEH13012.1 - 0.22 11.3 1.5 0.82 9.4 1.5 2.0 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like SET PF00856.28 CEH13013.1 - 3.2e-15 56.9 0.2 9e-13 48.9 0.0 3.6 3 1 0 3 3 3 2 SET domain Aa_trans PF01490.18 CEH13014.1 - 1e-18 67.3 19.2 2.2e-18 66.2 19.2 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PS_Dcarbxylase PF02666.15 CEH13015.1 - 3e-49 167.3 0.0 5.2e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2742 PF10888.8 CEH13015.1 - 0.037 14.3 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) Endotoxin_N PF03945.14 CEH13015.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain EMC3_TMCO1 PF01956.16 CEH13016.1 - 0.37 10.5 3.6 0.97 9.1 3.6 1.8 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like HIP1_clath_bdg PF16515.5 CEH13016.1 - 1.7 9.3 11.3 2.3 8.9 1.0 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GLTSCR1 PF15249.6 CEH13016.1 - 4.5 7.8 7.9 3.2 8.3 1.9 2.6 1 1 2 3 3 3 0 Conserved region of unknown function on GLTSCR protein Ribonuclease PF00545.20 CEH13017.1 - 1.5e-06 28.8 0.5 3.6e-06 27.6 0.4 1.6 1 1 1 2 2 2 1 ribonuclease Exo_endo_phos PF03372.23 CEH13018.1 - 0.00043 19.9 0.0 0.0035 16.9 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Asp PF00026.23 CEH13019.1 - 2.1e-72 244.2 0.5 1.2e-71 241.8 0.5 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEH13019.1 - 1.9e-12 47.8 0.8 4.9e-09 36.7 0.2 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal DUF3106 PF11304.8 CEH13019.1 - 0.29 11.6 1.6 0.45 11.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) adh_short PF00106.25 CEH13020.1 - 2.4e-35 121.8 0.0 1.4e-34 119.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH13020.1 - 9.2e-26 90.8 0.0 1.2e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH13020.1 - 0.0023 17.8 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CEH13020.1 - 0.0037 16.7 0.0 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Amidohydro_3 PF07969.11 CEH13021.1 - 4.6e-59 201.1 0.7 1.5e-40 140.1 0.6 2.0 1 1 1 2 2 2 2 Amidohydrolase family Peptidase_C65 PF10275.9 CEH13024.1 - 3.2e-44 151.2 0.0 7.5e-23 81.2 0.0 2.1 1 1 1 2 2 2 2 Peptidase C65 Otubain OTU PF02338.19 CEH13024.1 - 7.1e-05 23.3 0.0 0.00014 22.3 0.0 1.5 1 1 0 1 1 1 1 OTU-like cysteine protease Rv2175c_C PF18367.1 CEH13024.1 - 0.16 12.1 0.1 0.38 10.9 0.1 1.7 1 1 0 1 1 1 0 Rv2175c C-terminal domain of unknown function Vps35 PF03635.17 CEH13026.1 - 2.8e-90 303.9 0.4 3.3e-90 303.6 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Vps35 PF03635.17 CEH13027.1 - 8e-104 348.6 0.0 1e-103 348.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 HMG_box PF00505.19 CEH13028.1 - 1.4e-14 54.3 0.7 1.4e-14 54.3 0.7 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEH13028.1 - 5e-10 39.8 0.9 5e-10 39.8 0.9 1.5 1 1 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 CEH13028.1 - 0.052 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain Pantoate_ligase PF02569.15 CEH13029.1 - 6.3e-88 294.4 0.0 7.3e-88 294.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase 4HBT PF03061.22 CEH13030.1 - 0.046 14.1 0.2 0.13 12.6 0.2 1.7 1 0 0 1 1 1 0 Thioesterase superfamily 4HBT PF03061.22 CEH13031.1 - 0.064 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily Apt1 PF10351.9 CEH13033.1 - 3.7e-127 425.1 0.2 3.7e-127 425.1 0.2 5.2 6 0 0 6 6 6 2 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 CEH13033.1 - 7.2e-69 232.9 6.9 2.2e-68 231.3 2.9 2.7 2 1 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 CEH13033.1 - 7.2e-45 152.9 0.0 1.3e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CEH13033.1 - 9.5e-39 132.8 0.0 1.7e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CEH13033.1 - 2.5e-24 85.9 0.0 1.1e-23 83.9 0.0 2.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.9 CEH13033.1 - 0.00085 17.6 0.1 0.0018 16.5 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Mg_trans_NIPA PF05653.14 CEH13035.1 - 4.1e-61 206.7 0.0 3.1e-57 194.0 0.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 CEH13035.1 - 0.0003 21.0 2.0 0.0003 21.0 2.0 3.2 2 1 0 2 2 2 1 EamA-like transporter family SLC35F PF06027.12 CEH13035.1 - 0.092 12.2 0.0 0.092 12.2 0.0 1.6 2 0 0 2 2 2 0 Solute carrier family 35 AAA PF00004.29 CEH13036.1 - 6e-61 204.7 0.0 4.4e-45 153.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEH13036.1 - 1.2e-08 35.5 2.0 0.0081 16.6 0.0 4.7 4 0 0 4 4 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 CEH13036.1 - 2.2e-06 27.3 3.5 0.011 15.5 0.1 3.1 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CEH13036.1 - 2e-05 24.4 0.0 0.0054 16.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEH13036.1 - 2.5e-05 24.3 0.1 0.031 14.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEH13036.1 - 4.9e-05 23.6 0.2 0.028 14.7 0.1 3.5 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CEH13036.1 - 0.00016 22.0 0.1 0.61 10.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 CEH13036.1 - 0.00055 19.2 0.0 2.1 7.4 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CEH13036.1 - 0.00089 19.8 0.0 0.034 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEH13036.1 - 0.001 19.3 1.1 0.47 10.6 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 CEH13036.1 - 0.0017 18.0 0.4 0.032 13.8 0.1 3.0 3 1 1 4 4 4 1 AAA domain TIP49 PF06068.13 CEH13036.1 - 0.0019 17.5 0.2 0.042 13.1 0.0 2.4 3 0 0 3 3 2 1 TIP49 P-loop domain ATPase PF06745.13 CEH13036.1 - 0.0023 17.3 0.1 0.0059 16.0 0.0 1.6 2 0 0 2 2 1 1 KaiC Sigma54_activat PF00158.26 CEH13036.1 - 0.0026 17.5 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 CEH13036.1 - 0.0032 17.2 0.0 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 CEH13036.1 - 0.0033 17.4 0.1 0.27 11.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 CEH13036.1 - 0.0056 16.8 0.0 0.021 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 CEH13036.1 - 0.0059 16.6 0.0 0.82 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 CEH13036.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 CEH13036.1 - 0.017 14.5 0.3 0.059 12.7 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CEH13036.1 - 0.025 14.9 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 CEH13036.1 - 0.031 14.2 1.0 4.4 7.2 0.1 2.8 2 0 0 2 2 2 0 NACHT domain Vps4_C PF09336.10 CEH13036.1 - 0.044 13.8 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain PhoH PF02562.16 CEH13036.1 - 0.049 13.1 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 CEH13036.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CEH13036.1 - 0.096 12.4 0.1 0.25 11.0 0.1 1.7 2 0 0 2 2 1 0 AAA domain IATP PF04568.12 CEH13037.1 - 0.074 13.5 3.0 0.077 13.4 3.0 1.1 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF4140 PF13600.6 CEH13037.1 - 0.083 13.3 0.6 0.083 13.3 0.6 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 CEH13037.1 - 0.12 12.6 3.1 0.15 12.3 3.1 1.1 1 0 0 1 1 1 0 Haemolysin XhlA DivIC PF04977.15 CEH13037.1 - 0.19 11.5 3.7 0.22 11.3 3.7 1.1 1 0 0 1 1 1 0 Septum formation initiator ATP_sub_h PF10775.9 CEH13038.1 - 1.7e-24 85.6 1.4 3e-24 84.8 1.4 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h FYVE PF01363.21 CEH13039.1 - 0.021 14.9 3.3 0.044 13.9 3.3 1.4 1 0 0 1 1 1 0 FYVE zinc finger Erg28 PF03694.13 CEH13040.1 - 1.7e-37 128.2 1.9 2.1e-37 127.9 1.9 1.1 1 0 0 1 1 1 1 Erg28 like protein LIM PF00412.22 CEH13042.1 - 1.8e-19 69.7 15.6 6.2e-11 42.4 4.0 2.8 2 1 0 2 2 2 2 LIM domain zf-ACC PF17848.1 CEH13042.1 - 1.3 9.2 6.0 1.7 8.8 0.2 3.2 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf_UBZ PF18439.1 CEH13042.1 - 2 8.1 11.0 13 5.5 0.1 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger S4 PF01479.25 CEH13043.1 - 1e-10 41.2 0.8 1e-10 41.2 0.8 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 CEH13043.1 - 3.7e-06 27.7 0.1 6.5e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 CEH13044.1 - 3.1e-20 71.9 5.0 1.7e-18 66.3 3.9 2.1 2 0 0 2 2 2 2 Ribosomal protein L21e Got1 PF04178.12 CEH13046.1 - 2.2e-12 47.4 0.0 2.4e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family CUE PF02845.16 CEH13048.1 - 2.5e-07 30.2 0.0 4.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 CEH13048.1 - 0.041 14.0 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) IATP PF04568.12 CEH13048.1 - 0.29 11.6 0.1 0.29 11.6 0.1 3.3 2 1 1 3 3 3 0 Mitochondrial ATPase inhibitor, IATP DSPc PF00782.20 CEH13051.1 - 4.7e-06 26.4 0.0 7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Acetyltransf_2 PF00797.17 CEH13053.1 - 2.6e-26 92.9 2.8 8.2e-24 84.7 2.8 2.2 1 1 0 1 1 1 1 N-acetyltransferase RhoGEF PF00621.20 CEH13055.1 - 2.5e-33 115.9 0.0 3.4e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 CEH13055.1 - 4.5e-19 68.4 5.9 8.1e-19 67.5 5.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 CEH13055.1 - 7.2e-05 23.3 0.0 0.0035 17.8 0.0 2.7 3 0 0 3 3 3 1 PH domain FYVE_2 PF02318.16 CEH13055.1 - 0.13 12.4 4.3 0.26 11.5 4.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger eIF2_C PF09173.11 CEH13057.1 - 1.1e-36 124.9 0.3 3.1e-36 123.5 0.3 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CEH13057.1 - 1.4e-22 80.2 1.6 1.3e-21 77.1 1.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CEH13057.1 - 2.7e-10 40.5 1.9 4.5e-10 39.8 0.2 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 CEH13057.1 - 0.00026 20.9 0.8 0.0031 17.4 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CEH13057.1 - 0.00055 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CEH13057.1 - 0.021 14.9 0.2 0.12 12.5 0.2 2.4 1 1 0 1 1 1 0 Dynamin family MMR_HSR1_Xtn PF16897.5 CEH13057.1 - 0.03 14.3 0.1 0.03 14.3 0.1 2.2 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 CEH13057.1 - 0.031 14.0 0.9 1.9 8.2 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mucin PF01456.17 CEH13058.1 - 0.019 15.0 1.3 0.023 14.7 1.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein HLH PF00010.26 CEH13059.1 - 6.7e-09 35.6 0.0 2e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.25 CEH13060.1 - 3.2e-56 190.6 0.2 1.4e-34 119.7 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH13060.1 - 3.3e-23 82.3 0.3 2.9e-15 56.3 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CEH13060.1 - 0.0054 15.7 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CEH13060.1 - 0.011 15.1 0.2 0.058 12.7 0.0 2.2 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 CEH13060.1 - 0.027 14.4 7.3 0.054 13.4 0.1 3.3 2 1 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 CEH13060.1 - 0.035 14.8 0.0 0.13 13.0 0.0 2.1 1 0 0 1 1 1 0 Protein kinase C terminal domain DUF1615 PF07759.12 CEH13060.1 - 0.25 10.5 0.5 0.41 9.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) SDH_alpha PF03313.15 CEH13061.1 - 3.7e-92 308.7 0.6 3.7e-92 308.7 0.6 1.6 2 0 0 2 2 2 1 Serine dehydratase alpha chain SDH_beta PF03315.15 CEH13061.1 - 1.5e-49 168.4 0.3 8.1e-49 166.0 0.0 2.3 2 1 0 2 2 2 1 Serine dehydratase beta chain OPT PF03169.15 CEH13062.1 - 8.5e-141 470.6 39.1 9.7e-141 470.4 39.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1242 PF06842.12 CEH13063.1 - 1.5e-17 63.1 1.0 2e-17 62.7 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.13 CEH13063.1 - 0.12 12.7 0.3 0.23 11.7 0.2 1.5 2 0 0 2 2 2 0 LST-1 protein HEM4 PF02602.15 CEH13064.1 - 7.1e-26 91.0 0.0 7.3e-18 64.8 0.0 2.5 2 0 0 2 2 2 2 Uroporphyrinogen-III synthase HemD Cyclin_N PF00134.23 CEH13066.1 - 4.8e-37 126.6 0.1 8.1e-37 125.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEH13066.1 - 2.9e-07 30.6 0.0 1e-06 28.9 0.0 2.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain FSA_C PF10479.9 CEH13066.1 - 0.37 8.9 5.4 0.57 8.2 5.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus LAG1-DNAbind PF09271.11 CEH13067.1 - 8.9e-19 68.6 0.0 5.6e-18 66.0 0.0 2.2 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 CEH13067.1 - 2.7e-07 30.9 0.0 6.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF4519 PF15012.6 CEH13068.1 - 2 8.6 5.5 3.3 7.9 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Syja_N PF02383.18 CEH13072.1 - 1.8e-87 293.7 0.2 2.3e-87 293.3 0.2 1.1 1 0 0 1 1 1 1 SacI homology domain RRM_1 PF00076.22 CEH13073.1 - 4.2e-11 42.5 0.0 1.4e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3602 PF12223.8 CEH13073.1 - 0.015 15.9 1.1 0.015 15.9 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) DUF2852 PF11014.8 CEH13073.1 - 0.12 12.6 0.2 0.93 9.7 0.0 2.5 2 2 2 4 4 4 0 Protein of unknown function (DUF2852) PDT PF00800.18 CEH13074.1 - 1.1e-23 83.9 0.0 1.3e-22 80.5 0.0 2.1 1 1 0 1 1 1 1 Prephenate dehydratase Adeno_VII PF03228.14 CEH13074.1 - 0.038 14.6 0.0 0.2 12.3 0.0 2.1 2 0 0 2 2 2 0 Adenoviral core protein VII Coq4 PF05019.13 CEH13075.1 - 3.4e-72 242.4 0.0 2.9e-61 206.6 0.0 2.1 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Secretin_N_2 PF07655.13 CEH13075.1 - 0.0027 18.2 3.9 0.0045 17.5 2.0 2.1 2 0 0 2 2 2 1 Secretin N-terminal domain BCIP PF13862.6 CEH13076.1 - 7.1e-35 120.7 0.0 8.5e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF765 PF05570.11 CEH13076.1 - 0.16 12.2 0.8 0.31 11.3 0.8 1.5 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) DNA_ligase_OB_2 PF14743.6 CEH13077.1 - 5.8e-18 64.7 0.1 1.9e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 CEH13077.1 - 1.1e-05 25.2 0.0 3.3e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain SWIM PF04434.17 CEH13077.1 - 0.08 12.6 0.4 0.17 11.6 0.4 1.5 1 0 0 1 1 1 0 SWIM zinc finger Ribosomal_L19e PF01280.20 CEH13077.1 - 8.8 6.4 8.3 0.14 12.2 0.6 2.0 2 0 0 2 2 2 0 Ribosomal protein L19e LXG PF04740.12 CEH13079.1 - 0.43 10.3 9.0 1.7 8.3 0.1 4.1 3 1 1 4 4 4 0 LXG domain of WXG superfamily Lum_binding PF00677.17 CEH13080.1 - 2.7e-39 133.0 0.0 1.8e-20 72.7 0.0 2.4 2 0 0 2 2 2 2 Lumazine binding domain Actin PF00022.19 CEH13081.1 - 9.4e-33 113.4 0.0 1e-29 103.4 0.0 3.0 3 0 0 3 3 3 2 Actin MreB_Mbl PF06723.13 CEH13081.1 - 1.9e-05 23.7 0.0 3.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein F5_F8_type_C PF00754.25 CEH13083.1 - 6.6e-08 32.7 0.1 2.8e-07 30.7 0.1 2.0 1 1 0 1 1 1 1 F5/8 type C domain Glyco_hydro_63 PF03200.16 CEH13083.1 - 9.5e-05 21.3 5.5 0.008 15.0 5.5 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Trehalase PF01204.18 CEH13083.1 - 0.00042 19.3 1.2 0.00042 19.3 1.2 1.5 2 0 0 2 2 2 1 Trehalase Bac_rhamnosid6H PF17389.2 CEH13083.1 - 0.003 16.9 0.3 0.0059 15.9 0.3 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain SBF PF01758.16 CEH13086.1 - 4.5e-47 160.2 12.6 8.5e-47 159.4 12.6 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family Tim44 PF04280.15 CEH13087.1 - 2.7e-34 118.4 0.0 5.4e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 Tim44-like domain CENP-O PF09496.10 CEH13087.1 - 0.027 14.5 0.2 0.076 13.0 0.3 1.7 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component DUF3435 PF11917.8 CEH13087.1 - 0.029 13.3 0.1 0.045 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) B277 PF17623.2 CEH13087.1 - 0.091 11.8 0.2 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function Mis12 PF05859.12 CEH13089.1 - 2.1e-28 99.1 0.1 4.2e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 Mis12 protein DUF2992 PF11208.8 CEH13089.1 - 0.095 12.9 2.7 0.061 13.6 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) DNA_pol3_delta2 PF13177.6 CEH13090.1 - 5.2e-11 42.6 0.0 8.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CEH13090.1 - 9.8e-06 26.0 0.1 2.5e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CEH13090.1 - 0.00026 21.3 0.1 0.00099 19.5 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 CEH13090.1 - 0.0057 16.9 0.2 0.046 14.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 CEH13090.1 - 0.0082 16.1 0.0 0.02 14.8 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 CEH13090.1 - 0.012 15.8 0.5 0.14 12.4 0.2 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CEH13090.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Glyco_hydro_25 PF01183.20 CEH13092.1 - 2e-46 158.4 0.2 2.3e-46 158.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Nefa_Nip30_N PF10187.9 CEH13093.1 - 0.082 13.3 2.6 0.16 12.3 2.6 1.5 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Beta-APP PF03494.13 CEH13095.1 - 0.077 12.9 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) SepRS_C PF18006.1 CEH13097.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 O-phosphoseryl-tRNA synthetase C-terminal domain DUF2380 PF09533.10 CEH13098.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) SyrA PF11089.8 CEH13099.1 - 0.11 12.6 0.2 0.22 11.6 0.2 1.4 1 0 0 1 1 1 0 Exopolysaccharide production repressor MFS_1 PF07690.16 CEH13100.1 - 8.4e-25 87.4 20.9 8.4e-25 87.4 20.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Arylsulfotran_2 PF14269.6 CEH13101.1 - 2.1e-53 181.7 10.7 1.6e-46 159.1 4.2 2.1 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 CEH13101.1 - 7.1e-12 44.9 6.0 1.2e-11 44.1 6.0 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) OTU PF02338.19 CEH13104.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 OTU-like cysteine protease Acyl_transf_1 PF00698.21 CEH13107.1 - 3.5e-05 23.5 13.9 0.0012 18.4 0.0 4.4 4 1 0 4 4 4 2 Acyl transferase domain Pur_DNA_glyco PF02245.16 CEH13107.1 - 0.16 11.4 0.6 1.4 8.3 0.1 2.5 3 0 0 3 3 3 0 Methylpurine-DNA glycosylase (MPG) Flavoprotein PF02441.19 CEH13109.1 - 4.1e-49 166.3 0.1 1.1e-48 165.0 0.1 1.8 2 0 0 2 2 2 1 Flavoprotein VPS9 PF02204.18 CEH13109.1 - 2.2e-19 69.6 0.0 9.9e-19 67.5 0.0 1.9 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Staph_haemo PF05480.11 CEH13110.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Staphylococcus haemolytic protein UIM PF02809.20 CEH13111.1 - 0.0097 15.8 0.5 0.028 14.3 0.5 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif RCC1 PF00415.18 CEH13113.1 - 3e-10 40.6 9.9 0.094 13.4 0.2 8.1 9 0 0 9 9 9 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEH13113.1 - 3.6e-08 33.0 12.7 6.6e-05 22.6 0.0 6.7 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Auxin_repressed PF05564.12 CEH13115.1 - 0.073 13.8 0.3 0.073 13.8 0.3 2.9 3 1 0 3 3 3 0 Dormancy/auxin associated protein BTB PF00651.31 CEH13115.1 - 0.19 12.0 0.1 0.37 11.0 0.1 1.4 1 0 0 1 1 1 0 BTB/POZ domain Abhydrolase_6 PF12697.7 CEH13116.1 - 2.4e-11 44.7 0.0 3.8e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH13116.1 - 3.2e-09 36.4 0.0 6.5e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH13116.1 - 1.9e-07 31.0 0.2 1.7e-06 27.9 0.2 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF4978 PF16349.5 CEH13116.1 - 0.0031 17.2 1.4 0.0052 16.4 0.3 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4978) Peptidase_S9 PF00326.21 CEH13116.1 - 0.018 14.5 0.6 1.4 8.3 0.2 3.1 1 1 1 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_8 PF06259.12 CEH13116.1 - 0.035 13.8 0.4 0.079 12.6 0.3 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase RRM_1 PF00076.22 CEH13117.1 - 9.6e-41 137.5 0.0 2.5e-14 52.9 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEH13117.1 - 1.2e-05 25.3 0.0 2.1 8.5 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 CEH13117.1 - 0.0016 18.3 0.0 0.29 11.0 0.0 3.6 4 1 0 4 4 4 1 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 CEH13117.1 - 0.0084 15.9 0.0 2.8 7.7 0.0 3.1 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 CEH13117.1 - 0.024 14.7 0.0 14 5.8 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif TPR_16 PF13432.6 CEH13117.1 - 0.05 14.3 1.9 0.14 12.8 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ysc84 PF04366.12 CEH13118.1 - 5.1e-39 133.0 0.7 1.2e-38 131.7 0.4 1.8 2 0 0 2 2 2 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CEH13118.1 - 4.3e-11 42.3 0.0 8.5e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEH13118.1 - 1.1e-10 41.2 0.0 2.5e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEH13118.1 - 6.6e-09 35.3 0.1 9.1e-08 31.7 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain DUF3104 PF11302.8 CEH13118.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) UPF0242 PF06785.11 CEH13119.1 - 0.026 14.6 2.6 0.041 14.0 2.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XkdW PF09636.10 CEH13119.1 - 0.24 11.5 1.5 0.46 10.6 1.5 1.5 1 1 0 1 1 1 0 XkdW protein DUF3450 PF11932.8 CEH13119.1 - 0.25 10.6 2.8 0.7 9.2 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HALZ PF02183.18 CEH13119.1 - 0.77 10.0 5.4 0.39 11.0 1.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper YabA PF06156.13 CEH13119.1 - 0.95 10.1 4.4 3.8 8.2 4.4 2.0 1 1 0 1 1 1 0 Initiation control protein YabA PI3K_P85_iSH2 PF16454.5 CEH13120.1 - 0.032 13.8 0.2 0.033 13.8 0.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Enkurin PF13864.6 CEH13120.1 - 0.045 14.2 0.8 0.083 13.3 0.8 1.3 1 0 0 1 1 1 0 Calmodulin-binding XhlA PF10779.9 CEH13120.1 - 1.2 9.4 4.8 0.41 10.9 2.0 1.7 2 1 0 2 2 2 0 Haemolysin XhlA ETRAMP PF09716.10 CEH13120.1 - 3.4 7.8 6.0 0.81 9.8 0.3 2.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) GSH-S_N PF02951.14 CEH13121.1 - 0.0024 18.0 3.8 0.5 10.5 0.2 2.2 1 1 1 2 2 2 2 Prokaryotic glutathione synthetase, N-terminal domain IFT46_B_C PF12317.8 CEH13121.1 - 0.062 13.0 0.6 0.071 12.8 0.6 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF5633 PF18656.1 CEH13122.1 - 0.088 12.7 2.7 0.8 9.6 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5633) ParE_toxin PF05016.15 CEH13124.1 - 0.3 11.7 3.6 0.35 11.5 0.7 2.5 2 1 1 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE Spc7 PF08317.11 CEH13124.1 - 0.79 8.5 17.8 1.5 7.6 17.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Ribosomal_L29 PF00831.23 CEH13124.1 - 3.3 7.7 9.9 2.5 8.1 1.6 2.9 2 1 0 2 2 2 0 Ribosomal L29 protein Sec2p PF06428.11 CEH13124.1 - 4.7 7.3 14.8 3.6 7.6 10.0 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p YflT PF11181.8 CEH13126.1 - 0.053 14.0 5.7 0.53 10.8 1.6 2.7 2 0 0 2 2 2 0 Heat induced stress protein YflT 5_nucleotid PF05761.14 CEH13126.1 - 2.7 6.8 6.8 4.5 6.1 6.8 1.4 1 0 0 1 1 1 0 5' nucleotidase family TMCO5 PF14992.6 CEH13127.1 - 3.5 7.1 8.6 25 4.3 8.6 1.8 1 1 0 1 1 1 0 TMCO5 family HalX PF08663.10 CEH13128.1 - 0.043 14.1 4.2 0.043 14.1 4.2 2.2 2 1 1 3 3 3 0 HalX domain DUF3685 PF12452.8 CEH13128.1 - 0.088 12.5 0.5 0.13 12.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) YlqD PF11068.8 CEH13128.1 - 0.24 11.8 6.8 0.4 11.1 6.8 1.3 1 0 0 1 1 1 0 YlqD protein DDE_Tnp_IS66 PF03050.14 CEH13128.1 - 1.2 8.6 11.0 1.8 8.0 11.0 1.2 1 0 0 1 1 1 0 Transposase IS66 family LMP PF04778.12 CEH13131.1 - 0.0043 17.0 4.4 0.007 16.3 4.4 1.3 1 0 0 1 1 1 1 LMP repeated region SlyX PF04102.12 CEH13131.1 - 0.072 13.7 0.5 4.9 7.8 0.1 2.6 2 1 0 2 2 2 0 SlyX PKcGMP_CC PF16808.5 CEH13131.1 - 1.1 9.2 9.2 0.52 10.2 0.2 3.1 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0184 PF03670.13 CEH13133.1 - 0.035 14.5 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Spc7 PF08317.11 CEH13134.1 - 0.16 10.8 33.6 0.037 12.9 17.9 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 CEH13134.1 - 0.33 10.3 35.5 0.018 14.4 10.8 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fzo_mitofusin PF04799.13 CEH13134.1 - 1.1 8.8 18.9 4 6.9 2.9 3.5 4 0 0 4 4 4 0 fzo-like conserved region YabA PF06156.13 CEH13138.1 - 0.029 15.0 5.4 0.029 15.0 5.4 3.5 1 1 2 4 4 4 0 Initiation control protein YabA PRKG1_interact PF15898.5 CEH13138.1 - 0.045 14.7 26.3 0.72 10.8 7.9 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain APC_N_CC PF16689.5 CEH13138.1 - 0.049 13.7 7.6 0.077 13.1 5.2 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain FOXP-CC PF16159.5 CEH13138.1 - 0.22 12.2 5.5 1.6 9.4 2.1 2.9 2 0 0 2 2 2 0 FOXP coiled-coil domain HALZ PF02183.18 CEH13138.1 - 1.8 8.8 20.2 0.72 10.1 0.4 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.8 CEH13138.1 - 3.7 7.6 21.8 3.9 7.5 8.9 3.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 CEH13140.1 - 0.021 13.7 3.2 0.024 13.5 3.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2597 PF10772.9 CEH13140.1 - 0.039 14.0 0.1 0.051 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) DUF29 PF01724.16 CEH13140.1 - 0.051 13.8 1.5 0.061 13.5 1.0 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF29 Vma12 PF11712.8 CEH13140.1 - 0.081 13.0 0.0 0.085 12.9 0.0 1.3 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase 3-PAP PF12578.8 CEH13140.1 - 0.32 10.7 0.2 0.32 10.7 0.2 1.9 2 0 0 2 2 2 0 Myotubularin-associated protein DUF724 PF05266.14 CEH13140.1 - 0.72 9.7 4.5 0.88 9.4 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PRKG1_interact PF15898.5 CEH13140.1 - 1.9 9.5 6.4 2.9 8.8 6.4 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Cep57_CLD_2 PF14197.6 CEH13140.1 - 2.9 8.1 11.1 6.7 6.9 4.4 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF4407 PF14362.6 CEH13140.1 - 3.1 7.1 9.5 1.9 7.8 8.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 CEH13141.1 - 1.3e-06 28.2 81.1 0.0053 16.7 10.9 5.8 3 2 2 5 5 5 3 TATA element modulatory factor 1 DNA binding HAP1_N PF04849.13 CEH13141.1 - 0.27 10.4 46.8 0.3 10.3 14.5 2.7 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Cob_adeno_trans PF01923.18 CEH13141.1 - 1.2 9.3 17.4 0.043 14.0 2.9 3.2 1 1 3 4 4 4 0 Cobalamin adenosyltransferase MAD PF05557.13 CEH13141.1 - 1.8 6.9 56.5 28 2.9 29.6 2.6 1 1 1 2 2 2 0 Mitotic checkpoint protein ATG16 PF08614.11 CEH13141.1 - 2.2 8.4 56.2 0.16 12.1 12.0 3.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 CEH13141.1 - 2.7 6.5 46.1 0.42 9.2 18.3 2.1 1 1 1 2 2 2 0 AAA domain BLOC1_2 PF10046.9 CEH13141.1 - 2.8 8.3 40.5 0.082 13.2 7.6 5.1 3 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 CEH13141.1 - 3.5 8.0 57.0 9.5 6.6 19.3 3.5 1 1 1 2 2 1 0 Fez1 Fib_alpha PF08702.10 CEH13141.1 - 4 7.6 39.3 0.16 12.2 6.8 4.5 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 CEH13141.1 - 6.2 7.4 45.4 1.1 9.8 4.5 5.0 1 1 3 4 4 4 0 Protein of unknown function DUF16 DUF3450 PF11932.8 CEH13141.1 - 8.5 5.6 37.9 0.11 11.8 6.2 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF641 PF04859.12 CEH13141.1 - 9.8 6.5 48.1 2.6 8.4 6.7 5.8 1 1 5 6 6 6 0 Plant protein of unknown function (DUF641) DUF3053 PF11254.8 CEH13143.1 - 0.044 13.4 0.8 0.073 12.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) DUF3552 PF12072.8 CEH13144.1 - 0.0078 15.7 3.8 0.0088 15.5 3.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) PKcGMP_CC PF16808.5 CEH13144.1 - 0.37 10.7 11.5 0.45 10.4 0.7 3.5 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAM76 PF16046.5 CEH13144.1 - 4.9 6.4 5.9 17 4.6 6.0 1.7 1 1 0 1 1 1 0 FAM76 protein WD40 PF00400.32 CEH13145.1 - 8.8e-36 121.3 15.0 7.3e-07 29.8 0.3 7.9 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH13145.1 - 5.6e-14 52.2 0.4 8.7e-05 22.7 0.0 5.4 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 CEH13145.1 - 1.4e-09 37.4 2.1 3.4e-09 36.1 2.1 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 CEH13145.1 - 0.00034 19.7 0.0 4.3 6.2 0.0 4.2 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein HMMR_C PF15908.5 CEH13145.1 - 0.033 14.4 0.3 0.13 12.5 0.0 2.0 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal HsbA PF12296.8 CEH13146.1 - 0.012 16.1 0.7 0.019 15.4 0.7 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Zn_clus PF00172.18 CEH13149.1 - 0.0017 18.5 5.8 0.0017 18.5 5.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 CEH13150.1 - 7.9e-13 48.7 0.0 3.2e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 NAD(P)H-binding Protoglobin PF11563.8 CEH13150.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protoglobin LIP PF03583.14 CEH13152.1 - 2.6e-47 161.5 0.7 3.6e-47 161.1 0.7 1.2 1 0 0 1 1 1 1 Secretory lipase DUF829 PF05705.14 CEH13152.1 - 0.083 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) HsbA PF12296.8 CEH13153.1 - 0.00046 20.6 0.6 0.00068 20.1 0.6 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A SecD_SecF PF02355.16 CEH13153.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein export membrane protein HsbA PF12296.8 CEH13154.1 - 1.1e-06 29.1 0.1 1.6e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF4449 PF14613.6 CEH13156.1 - 2e-23 83.3 2.1 2e-23 83.3 2.1 4.0 3 2 0 3 3 3 1 Protein of unknown function (DUF4449) DUF1910 PF08928.10 CEH13156.1 - 0.13 12.3 0.2 0.56 10.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) RBM39linker PF15519.6 CEH13159.1 - 2.4 9.3 6.3 1.8 9.7 1.3 3.1 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Sec7 PF01369.20 CEH13160.1 - 3.3e-30 105.1 0.0 5.1e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain SAM_1 PF00536.30 CEH13160.1 - 7.9e-06 26.2 0.0 1.7e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CEH13160.1 - 7.8e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 CEH13160.1 - 0.024 15.1 0.0 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 PH domain Iso_dh PF00180.20 CEH13161.1 - 2.4e-79 267.0 0.0 3e-79 266.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase His_biosynth PF00977.21 CEH13163.1 - 1.2e-19 70.8 0.1 9.3e-10 38.3 0.0 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 CEH13163.1 - 0.064 12.6 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Pectinesterase PF01095.19 CEH13164.1 - 1e-10 40.8 0.7 2.1e-10 39.8 0.7 1.5 1 1 0 1 1 1 1 Pectinesterase RRM_1 PF00076.22 CEH13165.1 - 7e-26 89.9 0.0 2.1e-13 49.9 0.0 4.9 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEH13165.1 - 0.0049 17.0 0.0 0.022 14.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif PMT PF02366.18 CEH13167.1 - 1.2e-79 267.3 15.8 2.5e-79 266.3 15.8 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CEH13167.1 - 5.5e-67 225.2 4.6 5.5e-67 225.2 4.6 2.9 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CEH13167.1 - 1.3e-16 61.0 3.0 4.8e-16 59.1 1.0 2.0 1 1 1 2 2 2 2 MIR domain DUF2975 PF11188.8 CEH13167.1 - 1.5 8.7 6.5 0.21 11.5 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) LIP PF03583.14 CEH13168.1 - 9.5e-55 185.9 0.0 1.3e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase ABC_tran PF00005.27 CEH13169.1 - 6.9e-24 84.9 0.0 2e-23 83.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CEH13169.1 - 5.4e-09 36.3 1.3 0.0021 17.9 0.4 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEH13169.1 - 1.3e-06 28.1 0.3 0.0069 15.8 0.0 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 CEH13169.1 - 0.00012 22.1 0.2 0.00012 22.1 0.2 2.3 3 0 0 3 3 3 1 ABC transporter MMR_HSR1 PF01926.23 CEH13169.1 - 0.0013 18.8 0.4 0.0032 17.5 0.4 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CEH13169.1 - 0.0019 17.9 0.0 0.0088 15.8 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 CEH13169.1 - 0.0027 17.9 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_23 PF13476.6 CEH13169.1 - 0.013 16.1 0.0 0.03 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CEH13169.1 - 0.014 15.8 0.0 0.23 11.8 0.0 2.4 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.6 CEH13169.1 - 0.016 15.7 0.0 0.36 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CEH13169.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 CEH13169.1 - 0.023 14.6 0.1 0.058 13.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 CEH13169.1 - 0.049 12.6 0.1 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CEH13169.1 - 0.062 13.0 0.1 0.24 11.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CEH13169.1 - 0.11 12.1 0.2 0.21 11.3 0.1 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CEH13169.1 - 0.13 12.5 0.1 0.39 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain Thymidylat_synt PF00303.19 CEH13170.1 - 2.2e-87 292.6 0.0 2.4e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.22 CEH13171.1 - 2.6e-28 99.0 0.1 3.6e-28 98.6 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RVT_1 PF00078.27 CEH13174.1 - 0.022 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Zn_Tnp_IS1595 PF12760.7 CEH13175.1 - 0.055 13.5 0.3 0.055 13.5 0.3 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-RVT PF13966.6 CEH13175.1 - 0.55 11.0 3.8 0.38 11.5 1.4 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase HMG_CoA_synt_N PF01154.17 CEH13176.1 - 3.4e-86 287.5 0.1 6.6e-86 286.6 0.1 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 CEH13176.1 - 5.5e-83 278.8 0.2 1.8e-82 277.2 0.2 1.7 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 CEH13176.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SLAC1 PF03595.17 CEH13177.1 - 1.7e-81 274.0 46.5 2e-81 273.8 46.5 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel FF PF01846.19 CEH13178.1 - 5.6e-13 48.8 0.0 2.2e-09 37.3 0.0 3.7 3 0 0 3 3 3 2 FF domain WW PF00397.26 CEH13178.1 - 7.2e-07 29.2 16.8 0.00013 21.9 4.1 3.2 3 0 0 3 3 3 2 WW domain RRM_1 PF00076.22 CEH13178.1 - 3.6e-05 23.5 0.0 0.018 14.8 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin PF00085.20 CEH13179.1 - 1.2e-27 95.9 0.0 1.5e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEH13179.1 - 8.6e-09 35.8 0.2 1.7e-08 34.9 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CEH13179.1 - 2.5e-05 23.8 0.0 2.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CEH13179.1 - 0.00037 20.8 0.0 0.0012 19.1 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CEH13179.1 - 0.00074 19.3 0.0 0.0009 19.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CEH13179.1 - 0.00079 19.6 0.0 0.0023 18.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 CEH13179.1 - 0.0027 17.9 0.1 0.0096 16.1 0.1 1.9 2 1 0 2 2 2 1 Glutaredoxin AhpC-TSA PF00578.21 CEH13179.1 - 0.02 14.8 0.1 0.033 14.1 0.1 1.3 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_3 PF13192.6 CEH13179.1 - 0.11 12.6 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_6 PF13848.6 CEH13179.1 - 0.15 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain baeRF_family10 PF18854.1 CEH13180.1 - 0.056 13.7 0.3 0.056 13.7 0.3 3.1 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 10 Apis_Csd PF11671.8 CEH13180.1 - 6.1 6.8 5.5 14 5.6 5.5 1.6 1 0 0 1 1 1 0 Complementary sex determiner protein Kelch_4 PF13418.6 CEH13181.1 - 3.1e-32 110.3 12.8 8e-06 25.8 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 CEH13181.1 - 3.2e-31 106.6 4.0 3.2e-05 23.4 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CEH13181.1 - 1.3e-28 98.5 7.1 4.6e-06 26.5 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CEH13181.1 - 1.2e-27 95.6 13.9 8.4e-08 32.3 0.0 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 CEH13181.1 - 3.1e-24 84.4 10.7 6e-06 26.4 0.1 5.9 4 2 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CEH13181.1 - 3.7e-22 77.4 11.6 5.5e-07 29.3 0.1 6.3 6 0 0 6 6 6 5 Kelch motif MFS_1 PF07690.16 CEH13182.1 - 1.4e-33 116.3 30.8 1.4e-33 116.3 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH13182.1 - 1.2e-11 44.2 1.8 1.2e-11 44.2 1.8 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CEH13182.1 - 1.6e-06 26.8 2.0 2.4e-06 26.3 2.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 CEH13182.1 - 0.0094 14.2 0.1 0.017 13.3 0.1 1.4 1 0 0 1 1 1 1 BT1 family Zn_clus PF00172.18 CEH13183.1 - 0.0082 16.2 7.7 0.016 15.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.19 CEH13185.1 - 3.3e-11 43.6 0.5 2e-10 41.0 0.3 1.9 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family MFS_1 PF07690.16 CEH13188.1 - 1.2e-15 57.4 30.7 8.7e-12 44.6 25.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 CEH13188.1 - 1.5e-13 50.8 5.1 1.5e-13 50.8 5.1 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF3482 PF11981.8 CEH13188.1 - 1.3 8.4 6.8 0.059 12.8 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) TAF PF02969.17 CEH13189.1 - 2.2e-16 59.8 0.0 6.5e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 CEH13189.1 - 8.1e-13 48.5 0.2 2.1e-12 47.2 0.2 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 CEH13189.1 - 4.2e-05 23.9 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 LEAP-2 PF07359.11 CEH13190.1 - 0.0056 16.5 2.3 0.012 15.4 0.7 2.4 2 0 0 2 2 2 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Dickkopf_N PF04706.12 CEH13190.1 - 0.019 15.5 26.1 0.091 13.3 4.9 3.9 3 1 1 4 4 4 0 Dickkopf N-terminal cysteine-rich region EB PF01683.18 CEH13190.1 - 0.024 14.9 2.6 0.024 14.9 2.6 3.3 2 1 2 4 4 4 0 EB module AAA_33 PF13671.6 CEH13190.1 - 0.066 13.4 0.0 0.81 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF4229 PF14012.6 CEH13190.1 - 0.076 13.1 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) WD40 PF00400.32 CEH13191.1 - 1.6e-17 63.5 11.5 0.0025 18.6 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH13191.1 - 1.4e-09 38.2 0.1 0.037 14.3 0.0 5.1 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEH13191.1 - 5.9e-07 29.6 0.3 0.0014 18.6 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEH13191.1 - 0.00014 21.3 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 CEH13191.1 - 0.056 12.1 0.1 0.093 11.4 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 NUDIX_4 PF14815.6 CEH13192.1 - 1.3e-18 67.0 0.7 1.5e-09 37.8 0.0 2.9 2 1 0 2 2 2 2 NUDIX domain HhH-GPD PF00730.25 CEH13192.1 - 5.2e-15 55.8 0.0 1.2e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CEH13192.1 - 7.4e-09 35.0 0.0 2.5e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 CEH13192.1 - 5.3 7.5 10.7 12 6.4 10.7 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III zf-C2H2_jaz PF12171.8 CEH13196.1 - 4.1e-08 33.3 1.1 7.4e-08 32.5 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CEH13196.1 - 0.0063 16.8 0.0 0.0094 16.3 0.0 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CEH13196.1 - 0.029 14.8 0.3 0.05 14.0 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Ribosomal_L35Ae PF01247.18 CEH13197.1 - 1.6e-43 146.7 1.4 1.8e-43 146.6 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CEH13197.1 - 0.00039 20.6 0.1 0.53 10.5 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain MFS_1 PF07690.16 CEH13201.1 - 3e-32 111.9 30.0 3e-32 111.9 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH13201.1 - 3.2e-06 26.3 11.9 1.4e-05 24.2 8.7 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Amidinotransf PF02274.17 CEH13203.1 - 1.3e-05 24.4 0.0 7.3e-05 22.0 0.0 1.9 2 1 1 3 3 3 1 Amidinotransferase PepSY_2 PF13670.6 CEH13203.1 - 0.081 12.9 0.7 7.1 6.7 0.0 2.6 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Fungal_trans PF04082.18 CEH13205.1 - 5.1e-07 29.0 0.0 0.0021 17.2 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH13205.1 - 9.3e-05 22.5 9.1 0.00017 21.7 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_1 PF00300.22 CEH13206.1 - 1.7e-38 132.3 0.0 2e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MMtag PF10159.9 CEH13207.1 - 1.2e-28 99.2 5.4 1.2e-28 99.2 5.4 2.8 2 1 0 2 2 2 1 Multiple myeloma tumor-associated LSM PF01423.22 CEH13207.1 - 7.7e-08 31.9 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEH13207.1 - 0.21 11.8 0.0 0.43 10.8 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain RRP14 PF15459.6 CEH13207.1 - 1 10.0 6.5 9.6 6.9 0.6 3.0 3 0 0 3 3 3 0 60S ribosome biogenesis protein Rrp14 YlbD_coat PF14071.6 CEH13212.1 - 0.17 12.1 0.1 0.28 11.5 0.1 1.2 1 0 0 1 1 1 0 Putative coat protein CsbD PF05532.12 CEH13213.1 - 0.00042 20.2 0.5 0.00097 19.0 0.5 1.6 1 0 0 1 1 1 1 CsbD-like Ubiq_cyt_C_chap PF03981.12 CEH13214.1 - 1.8e-27 96.1 0.0 6.9e-25 87.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone HSP70 PF00012.20 CEH13215.1 - 3.5e-65 220.4 0.5 3.5e-65 220.4 0.5 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CEH13215.1 - 1.3e-06 27.5 2.7 2.3e-05 23.4 0.6 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin PF00022.19 CEH13215.1 - 4.5e-06 25.5 0.2 0.007 15.0 0.1 2.2 2 0 0 2 2 2 2 Actin PilM_2 PF11104.8 CEH13215.1 - 0.00016 20.8 0.0 0.41 9.6 0.0 2.4 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; FtsA PF14450.6 CEH13215.1 - 0.00047 20.5 0.9 0.0032 17.9 0.6 2.6 1 1 0 1 1 1 1 Cell division protein FtsA Alpha_L_fucos PF01120.17 CEH13215.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-fucosidase eIF-3c_N PF05470.12 CEH13216.1 - 5.8e-137 457.5 3.6 6.8e-137 457.3 3.6 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CEH13216.1 - 4.5e-14 52.8 0.0 3.2e-13 50.1 0.0 2.4 2 0 0 2 2 2 1 PCI domain eIF-3c_N PF05470.12 CEH13217.1 - 1.8e-18 66.2 2.7 2.1e-18 66.0 2.7 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus VirJ PF06057.11 CEH13217.1 - 0.052 13.4 0.1 0.058 13.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Swi5 PF07061.11 CEH13217.1 - 0.081 13.0 0.8 0.17 12.0 0.3 1.8 2 0 0 2 2 2 0 Swi5 AAA PF00004.29 CEH13218.1 - 2.1e-40 138.2 0.0 4e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CEH13218.1 - 5.6e-21 74.2 0.1 1.3e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CEH13218.1 - 0.00014 22.3 0.2 0.049 14.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CEH13218.1 - 0.00018 21.5 0.1 0.0019 18.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CEH13218.1 - 0.00049 20.3 0.1 0.0048 17.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CEH13218.1 - 0.00086 19.6 0.5 0.11 12.8 0.0 2.5 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CEH13218.1 - 0.0013 18.5 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 CEH13218.1 - 0.002 17.6 0.1 0.051 13.0 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_lid_3 PF17862.1 CEH13218.1 - 0.0075 16.0 0.1 0.047 13.5 0.1 2.3 1 1 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 CEH13218.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CEH13218.1 - 0.016 14.6 0.2 0.052 12.9 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CEH13218.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 CEH13218.1 - 0.053 13.3 0.2 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CEH13218.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CEH13218.1 - 0.13 11.9 0.1 0.31 10.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.9 CEH13218.1 - 0.14 12.2 1.8 0.36 10.9 1.8 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_25 PF13481.6 CEH13218.1 - 0.21 11.2 0.4 1.6 8.2 0.1 2.4 1 1 0 2 2 2 0 AAA domain Ribosomal_L4 PF00573.22 CEH13220.1 - 6.4e-40 136.9 0.5 6.4e-40 136.9 0.5 2.1 2 1 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CEH13220.1 - 1.5e-24 85.8 5.7 4.7e-24 84.2 5.7 1.8 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain SAP PF02037.27 CEH13222.1 - 6.2e-05 22.7 0.4 6.2e-05 22.7 0.4 1.9 2 0 0 2 2 2 1 SAP domain DEAD PF00270.29 CEH13223.1 - 8.6e-36 123.3 0.0 3e-18 66.2 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase DUF4217 PF13959.6 CEH13223.1 - 1.6e-23 82.7 0.2 3.4e-23 81.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 CEH13223.1 - 8.2e-18 64.8 0.0 2.9e-17 63.0 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH13223.1 - 0.0015 18.5 0.0 0.0051 16.8 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CEH13223.1 - 0.059 12.6 0.0 0.059 12.6 0.0 2.0 2 0 0 2 2 2 0 SecA DEAD-like domain CMS1 PF14617.6 CEH13223.1 - 0.07 12.5 0.0 0.07 12.5 0.0 3.2 3 1 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Phos_pyr_kin PF08543.12 CEH13224.1 - 3.1e-73 246.2 0.8 4.1e-51 173.7 0.0 3.2 2 1 1 3 3 3 3 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CEH13224.1 - 1.4e-28 100.2 0.1 2.2e-28 99.5 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Dynamin_M PF01031.20 CEH13225.1 - 2.3e-108 361.8 0.0 5.3e-108 360.6 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CEH13225.1 - 1.1e-55 188.3 0.0 1.8e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CEH13225.1 - 2.9e-27 94.6 0.9 2.9e-27 94.6 0.9 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CEH13225.1 - 4.8e-05 23.4 0.2 0.0011 19.1 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase TipAS PF07739.13 CEH13225.1 - 0.0099 16.4 0.0 0.033 14.7 0.0 1.8 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain AAA_16 PF13191.6 CEH13225.1 - 0.032 14.6 0.6 0.83 10.0 0.1 2.6 2 0 0 2 2 2 0 AAA ATPase domain RabGAP-TBC PF00566.18 CEH13226.1 - 1.3e-48 165.6 0.1 1.8e-48 165.0 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 CEH13226.1 - 0.00041 20.2 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.6 CEH13226.1 - 0.0043 17.5 0.3 0.46 11.0 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CEH13226.1 - 0.024 14.5 0.1 0.99 9.5 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain DUF2854 PF11016.8 CEH13227.1 - 0.2 11.6 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) PQ-loop PF04193.14 CEH13228.1 - 2e-17 62.7 1.3 1.7e-12 46.9 0.2 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 CEH13228.1 - 0.012 16.5 0.6 0.2 12.5 0.0 2.4 2 0 0 2 2 2 0 ER lumen protein retaining receptor DoxX_2 PF13564.6 CEH13228.1 - 0.036 14.2 2.4 0.065 13.3 0.3 2.2 2 0 0 2 2 2 0 DoxX-like family MAP65_ASE1 PF03999.12 CEH13230.1 - 0.041 12.6 3.3 2.1 7.0 0.1 2.8 3 0 0 3 3 3 0 Microtubule associated protein (MAP65/ASE1 family) DUF641 PF04859.12 CEH13230.1 - 0.042 14.2 0.5 0.12 12.7 0.5 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Golgin_A5 PF09787.9 CEH13230.1 - 0.046 13.2 1.7 0.084 12.3 1.7 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3405 PF11885.8 CEH13231.1 - 1.7e-80 271.1 6.6 2.9e-52 177.9 0.3 3.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) Wzz PF02706.15 CEH13231.1 - 0.15 12.4 0.1 0.27 11.6 0.1 1.3 1 0 0 1 1 1 0 Chain length determinant protein WD40 PF00400.32 CEH13233.1 - 2.4e-20 72.5 19.5 0.007 17.2 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH13233.1 - 9.8e-07 29.0 0.4 0.007 16.6 0.0 4.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain VCBS PF13517.6 CEH13233.1 - 0.11 13.1 0.1 0.75 10.4 0.1 2.4 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DNA_binding_1 PF01035.20 CEH13234.1 - 3.7e-21 75.1 0.0 5.7e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Periviscerokin PF08259.11 CEH13234.1 - 3.3 8.3 5.4 3.8 8.1 1.0 2.6 2 0 0 2 2 2 0 Periviscerokinin family Mg_trans_NIPA PF05653.14 CEH13235.1 - 1.2e-90 303.6 28.3 1.6e-90 303.2 28.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CEH13235.1 - 0.00094 19.4 14.9 0.00094 19.4 14.9 3.6 2 2 0 2 2 2 1 EamA-like transporter family DUF5362 PF17319.2 CEH13235.1 - 0.037 13.9 0.0 0.037 13.9 0.0 3.5 3 2 1 4 4 4 0 Family of unknown function (DUF5362) SKN1 PF03935.15 CEH13236.1 - 5.3e-171 569.4 5.3 9e-170 565.4 5.3 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Dabb PF07876.12 CEH13237.1 - 9.2e-16 58.3 0.2 1.1e-15 58.1 0.2 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1687 PF07955.11 CEH13238.1 - 4.8e-05 23.8 5.9 0.00024 21.6 5.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Glutaredoxin PF00462.24 CEH13239.1 - 2.2e-14 53.4 0.0 3.7e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 CEH13239.1 - 0.0054 17.1 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 CEH13239.1 - 0.17 11.6 0.0 22 4.8 0.0 2.2 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Dfp1_Him1_M PF08630.10 CEH13241.1 - 2.2e-32 111.9 0.3 6e-32 110.5 0.0 2.0 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 CEH13241.1 - 8.7e-19 67.4 0.4 2.1e-18 66.2 0.4 1.7 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 CEH13241.1 - 0.039 13.9 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 twin BRCT domain NUDIX PF00293.28 CEH13242.1 - 1.1e-13 51.3 0.4 1.3e-13 51.1 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 CEH13242.1 - 1.1e-05 25.4 0.4 2.5e-05 24.2 0.4 1.6 1 1 0 1 1 1 1 NUDIX domain Suc_Fer-like PF06999.12 CEH13243.1 - 2.4e-23 83.0 0.0 5.4e-23 81.9 0.0 1.6 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.27 CEH13243.1 - 4.7e-09 36.1 2.5 2.4e-08 33.8 2.5 2.1 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Zn_clus PF00172.18 CEH13244.1 - 0.0016 18.5 8.1 0.0052 16.9 8.1 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EBP50_C PF09007.11 CEH13244.1 - 0.93 10.5 9.5 0.37 11.8 5.1 2.4 2 1 0 2 2 2 0 EBP50, C-terminal ATP-synt_ab PF00006.25 CEH13245.1 - 2.2e-65 220.3 0.0 3.7e-65 219.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CEH13245.1 - 2.4e-12 47.2 0.9 4.4e-12 46.3 0.2 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 CEH13245.1 - 0.038 12.9 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TPR_20 PF14561.6 CEH13246.1 - 0.011 16.0 0.1 7.7 6.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 CEH13246.1 - 0.079 12.4 0.3 3.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Coatomer epsilon subunit Mito_carr PF00153.27 CEH13247.1 - 1.2e-61 204.6 1.6 2.1e-19 69.2 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Efg1 PF10153.9 CEH13248.1 - 1.5e-27 96.2 5.4 1.5e-27 96.2 5.4 1.6 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DUF3435 PF11917.8 CEH13248.1 - 0.015 14.3 4.9 0.024 13.6 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DEAD PF00270.29 CEH13249.1 - 2.8e-39 134.7 0.1 4.4e-39 134.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH13249.1 - 5.5e-28 97.5 0.9 3.6e-27 94.9 0.8 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH13249.1 - 1.1e-05 25.5 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC_5 PF14787.6 CEH13252.1 - 0.00012 21.7 0.8 0.00028 20.5 0.8 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 CEH13252.1 - 0.00054 19.9 0.5 0.00054 19.9 0.5 2.0 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 CEH13252.1 - 0.016 15.4 0.1 0.17 12.2 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 CEH13252.1 - 0.061 13.2 0.3 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 CEH13252.1 - 0.07 13.1 0.4 0.16 12.0 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Choline_transpo PF04515.12 CEH13253.1 - 3.6e-57 194.0 17.1 4e-57 193.9 17.1 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF5391 PF17369.2 CEH13253.1 - 0.071 13.1 4.5 1.1 9.4 0.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5391) GMC_oxred_C PF05199.13 CEH13254.1 - 3.2e-17 63.4 0.0 6.6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CEH13254.1 - 1.5e-16 60.6 0.0 2.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase PIG-L PF02585.17 CEH13256.1 - 3.9e-26 92.2 0.0 5.5e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Cas6 PF09559.10 CEH13256.1 - 0.15 12.0 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 Cas6 Crispr Bestrophin PF01062.21 CEH13258.1 - 1.5e-27 96.7 0.0 2.1e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF1772 PF08592.11 CEH13258.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF3792 PF12670.7 CEH13258.1 - 0.07 13.3 0.8 0.07 13.3 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Clat_adaptor_s PF01217.20 CEH13259.1 - 1.1e-10 41.6 0.0 1.5e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Mon1 PF03164.14 CEH13260.1 - 3.6e-95 319.4 0.0 7.1e-92 308.6 0.0 2.1 2 0 0 2 2 2 2 Trafficking protein Mon1 RF-1 PF00472.20 CEH13261.1 - 1.5e-19 70.0 2.5 1.5e-19 70.0 2.5 3.2 4 0 0 4 4 4 1 RF-1 domain Glyco_hydro_16 PF00722.21 CEH13262.1 - 5.6e-08 32.4 0.0 9.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DLH PF01738.18 CEH13263.1 - 2e-24 86.4 1.3 2.4e-24 86.1 1.3 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CEH13263.1 - 0.0035 17.0 0.0 0.024 14.3 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH13263.1 - 0.072 12.3 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 SARAF PF06682.12 CEH13264.1 - 3.2e-60 204.5 0.0 3.7e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis adh_short PF00106.25 CEH13265.1 - 8.6e-32 110.2 0.1 1.1e-31 109.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH13265.1 - 2.5e-24 86.2 0.0 3.2e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH13265.1 - 0.0024 17.8 0.1 0.0032 17.4 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CEH13265.1 - 0.0087 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) CDO_I PF05995.12 CEH13265.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Cysteine dioxygenase type I zf-SNAP50_C PF12251.8 CEH13266.1 - 3.2e-06 26.9 3.5 1.4e-05 24.9 0.0 3.0 3 1 0 3 3 3 1 snRNA-activating protein of 50kDa MW C terminal SLED PF12140.8 CEH13266.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 SLED domain TANGO2 PF05742.12 CEH13267.1 - 4.6e-52 177.6 0.0 4.8e-38 131.7 0.0 2.1 2 0 0 2 2 2 2 Transport and Golgi organisation 2 MIP PF00230.20 CEH13268.1 - 8.4e-42 143.4 14.9 1.2e-41 142.9 14.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein CAP_N PF01213.19 CEH13268.1 - 1.5 8.3 10.5 2.7 7.4 10.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 CEH13268.1 - 2.7 8.0 8.6 1.2 9.2 5.2 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator PRIMA1 PF16101.5 CEH13268.1 - 7.3 6.6 11.2 15 5.7 11.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MFS_1 PF07690.16 CEH13269.1 - 1.9e-22 79.7 37.2 2.2e-15 56.4 16.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH13269.1 - 1.2e-15 57.4 17.6 4.2e-15 55.6 17.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2583 PF10762.9 CEH13269.1 - 0.02 15.3 0.1 0.11 13.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) DUF4384 PF14326.6 CEH13271.1 - 0.068 13.3 0.1 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) MFS_1 PF07690.16 CEH13272.1 - 1.3e-37 129.5 44.3 1.8e-37 129.1 44.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RAI1 PF08652.11 CEH13273.1 - 1.1e-16 60.7 0.0 3.1e-16 59.3 0.0 1.8 1 1 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease PMAIP1 PF15150.6 CEH13273.1 - 0.12 12.2 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced PHA_gran_rgn PF09650.10 CEH13273.1 - 0.13 12.6 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Acyl-CoA_dh_1 PF00441.24 CEH13274.1 - 2.3e-41 141.5 1.2 2.3e-41 141.5 1.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEH13274.1 - 3.2e-36 124.4 0.0 8.7e-36 123.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CEH13274.1 - 3.3e-27 94.5 0.0 8.4e-27 93.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEH13274.1 - 4.7e-15 56.0 0.6 4.7e-15 56.0 0.6 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CEH13274.1 - 0.072 13.7 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Glyco_hydro_31 PF01055.26 CEH13275.1 - 5.5e-103 345.5 0.9 7.1e-103 345.1 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CEH13275.1 - 9.6e-08 32.2 0.7 4.5e-07 30.1 0.2 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF1388 PF07142.12 CEH13275.1 - 0.31 11.0 7.4 0.61 10.1 7.4 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) Aldose_epim PF01263.20 CEH13276.1 - 2.1e-56 191.4 0.0 2.7e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Het-C PF07217.11 CEH13277.1 - 5.3e-207 688.8 0.0 1.2e-206 687.7 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF2780 PF11075.8 CEH13277.1 - 0.074 13.2 0.7 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) Epimerase PF01370.21 CEH13278.1 - 7e-12 45.3 0.0 1.5e-11 44.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEH13278.1 - 4.9e-09 35.6 0.0 1.2e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CEH13278.1 - 8.7e-07 28.4 0.0 5.6e-06 25.7 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 CEH13278.1 - 4.5e-06 26.7 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CEH13278.1 - 0.00049 19.6 0.1 0.0059 16.1 0.0 2.5 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CEH13278.1 - 0.001 18.7 1.1 0.0018 17.9 0.2 1.9 2 1 0 2 2 2 1 NmrA-like family DUF3425 PF11905.8 CEH13279.1 - 7.1e-13 48.6 1.1 3e-12 46.6 0.2 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CEH13279.1 - 0.14 12.2 5.9 0.18 11.9 2.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor Vta1_C PF18097.1 CEH13280.1 - 0.33 10.7 2.4 2.4 8.0 0.7 2.1 2 0 0 2 2 2 0 Vta1 C-terminal domain Synaptobrevin PF00957.21 CEH13285.1 - 2e-25 88.4 1.1 2.6e-25 88.0 1.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CEH13285.1 - 5.4e-21 74.4 0.0 9.8e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain CTD_bind PF04818.13 CEH13287.1 - 0.0028 18.4 0.0 0.0057 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Zn-C2H2_12 PF18112.1 CEH13287.1 - 0.77 10.3 6.8 0.36 11.3 0.2 3.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf_UBZ PF18439.1 CEH13287.1 - 1.5 8.5 9.6 1.3 8.7 4.4 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger p450 PF00067.22 CEH13288.1 - 5.5e-77 259.5 0.0 4.5e-49 167.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MBOAT PF03062.19 CEH13289.1 - 9e-52 176.5 1.4 1.9e-51 175.5 0.0 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family CD24 PF14984.6 CEH13289.1 - 0.17 12.2 0.1 0.17 12.2 0.1 3.9 3 1 1 4 4 4 0 CD24 protein PITH PF06201.13 CEH13290.1 - 2.4e-32 112.2 0.0 9.1e-32 110.4 0.0 1.8 2 0 0 2 2 2 1 PITH domain DUF4031 PF13223.6 CEH13290.1 - 0.039 14.2 0.0 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4031) OxoDH_E1alpha_N PF12573.8 CEH13290.1 - 0.56 10.0 3.1 25 4.8 0.1 2.9 3 0 0 3 3 3 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Nop PF01798.18 CEH13291.1 - 9.7e-84 280.4 0.0 9.7e-84 280.4 0.0 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin DUF2431 PF10354.9 CEH13291.1 - 1.3e-29 103.6 0.0 2.9e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) UCH PF00443.29 CEH13292.1 - 5.3e-40 137.5 0.0 7.5e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CEH13292.1 - 4.9e-25 87.6 11.3 1.7e-20 73.1 0.7 2.7 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 CEH13292.1 - 5e-24 83.8 2.6 9.4e-23 79.7 0.5 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 CEH13292.1 - 2.7e-12 46.9 1.0 4.2e-05 23.3 0.0 4.4 4 1 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CEH13292.1 - 6e-07 29.3 2.0 9.2e-07 28.6 0.1 2.3 3 0 0 3 3 3 1 UBA/TS-N domain UBA_4 PF14555.6 CEH13292.1 - 0.025 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Ribosomal_L33 PF00471.20 CEH13292.1 - 0.15 12.6 1.9 3.8 8.0 0.2 2.5 2 0 0 2 2 2 0 Ribosomal protein L33 MitMem_reg PF13012.6 CEH13293.1 - 3.6e-31 107.9 0.5 6.2e-31 107.1 0.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CEH13293.1 - 4.7e-28 97.5 0.0 1.3e-27 96.2 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Nucleoside_tran PF01733.18 CEH13294.1 - 7.1e-29 101.2 7.0 2.6e-16 59.9 0.0 3.4 2 1 1 3 3 3 2 Nucleoside transporter ATP_bind_1 PF03029.17 CEH13295.1 - 5e-70 236.0 0.0 1.1e-69 234.9 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CEH13295.1 - 0.00023 21.2 0.0 0.001 19.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CEH13295.1 - 0.0025 18.3 0.7 0.0054 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEH13295.1 - 0.0066 16.9 0.0 0.024 15.0 0.0 1.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CEH13295.1 - 0.013 15.2 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 CEH13295.1 - 0.015 14.5 0.0 0.47 9.6 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.6 CEH13295.1 - 0.022 15.3 0.0 0.48 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 CEH13295.1 - 0.029 13.9 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_15 PF13175.6 CEH13295.1 - 0.043 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CEH13295.1 - 0.047 13.6 0.0 11 5.8 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_24 PF13479.6 CEH13295.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEH13295.1 - 0.082 13.1 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEH13295.1 - 0.09 13.3 0.0 0.21 12.1 0.0 1.7 2 0 0 2 2 1 0 ABC transporter Sigma54_activ_2 PF14532.6 CEH13295.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain FXR_C1 PF16096.5 CEH13295.1 - 0.14 12.4 1.0 0.57 10.4 0.0 2.4 3 0 0 3 3 3 0 Fragile X-related 1 protein C-terminal region 2 AAA_22 PF13401.6 CEH13295.1 - 0.17 12.2 0.0 0.5 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CEH13295.1 - 0.18 11.3 0.8 0.28 10.8 0.1 1.7 2 1 0 2 2 2 0 AAA domain Asp_protease PF09668.10 CEH13296.1 - 6.1e-59 197.2 0.0 9.1e-59 196.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEH13296.1 - 5.4e-21 75.0 0.0 1.7e-20 73.3 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEH13296.1 - 1.2e-10 41.9 0.0 5.1e-10 39.8 0.0 2.2 2 0 0 2 2 1 1 Aspartyl protease ubiquitin PF00240.23 CEH13296.1 - 2.4e-09 36.8 0.0 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 CEH13296.1 - 4e-06 26.6 0.0 7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CEH13296.1 - 0.00058 20.1 0.0 0.0019 18.5 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.31 CEH13296.1 - 0.00099 19.0 0.1 0.0023 17.8 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 CEH13296.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 CEH13296.1 - 0.0064 16.3 0.3 0.019 14.8 0.3 1.8 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_15 PF18403.1 CEH13296.1 - 0.014 15.3 2.0 0.92 9.4 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin-like domain Asp-B-Hydro_N PF05279.11 CEH13296.1 - 0.089 12.8 5.8 0.14 12.2 5.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TBK1_ULD PF18396.1 CEH13296.1 - 0.12 12.3 0.1 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain eIF3_subunit PF08597.10 CEH13296.1 - 0.22 11.4 6.3 0.39 10.6 6.3 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Condensation PF00668.20 CEH13297.1 - 0.0023 16.7 0.0 0.015 14.0 0.0 1.9 2 0 0 2 2 2 1 Condensation domain AATase PF07247.12 CEH13297.1 - 0.071 11.6 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Alcohol acetyltransferase MFS_1 PF07690.16 CEH13298.1 - 9.8e-42 143.1 26.1 9.8e-42 143.1 26.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH13298.1 - 5.9e-15 55.1 6.2 5.9e-15 55.1 6.2 2.5 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 CEH13298.1 - 3.5e-08 33.1 5.3 3.5e-08 33.1 5.3 2.7 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 CEH13298.1 - 0.00039 19.0 4.5 0.0008 17.9 4.5 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF5313 PF17240.2 CEH13298.1 - 0.14 12.6 0.1 0.14 12.6 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5313) acVLRF1 PF18859.1 CEH13298.1 - 0.15 12.3 1.3 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor Peptidase_S8 PF00082.22 CEH13300.1 - 1.7e-56 191.7 0.2 2.6e-56 191.1 0.2 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 CEH13300.1 - 2.5e-46 157.6 0.0 3.7e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II tRNA-synt_2b PF00587.25 CEH13301.1 - 1.1e-28 100.5 0.0 1.5e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEH13301.1 - 5e-05 23.4 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain DUF1749 PF08538.10 CEH13302.1 - 0.055 12.6 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.25 CEH13302.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) WD40 PF00400.32 CEH13303.1 - 4.5e-35 119.1 20.4 1e-06 29.3 0.0 9.2 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.7 CEH13303.1 - 1.8e-10 40.5 0.0 3.8e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEH13303.1 - 1.9e-09 37.2 0.0 4.7e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 CEH13303.1 - 9.9e-08 31.1 4.6 0.15 10.7 0.1 6.0 4 2 3 7 7 7 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 CEH13303.1 - 0.0034 17.2 0.2 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 F-box ANAPC4_WD40 PF12894.7 CEH13303.1 - 0.0061 16.8 0.4 2.9 8.3 0.0 4.1 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CRAL_TRIO PF00650.20 CEH13304.1 - 1.9e-30 105.7 0.0 3.1e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEH13304.1 - 3.7e-11 43.0 0.2 1.2e-10 41.4 0.2 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CEH13304.1 - 4.9e-05 23.5 0.0 8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Mucin PF01456.17 CEH13304.1 - 1.4 8.9 6.2 2.3 8.2 6.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DPM3 PF08285.11 CEH13306.1 - 7.8e-27 93.3 0.0 8.6e-27 93.2 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Glyco_hydro_3_C PF01915.22 CEH13307.1 - 5.8e-44 150.5 0.0 9.4e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CEH13307.1 - 9.7e-32 110.6 0.0 8.7e-31 107.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CEH13307.1 - 1.1e-23 83.1 0.5 2.1e-23 82.2 0.5 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain TolA_bind_tri PF16331.5 CEH13308.1 - 0.015 15.4 0.3 0.025 14.6 0.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF2259 PF10016.9 CEH13309.1 - 0.42 10.5 2.9 0.81 9.6 2.4 1.8 1 1 0 1 1 1 0 Predicted secreted protein (DUF2259) COMP PF11598.8 CEH13309.1 - 9.3 6.8 7.0 20 5.8 0.0 3.1 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein PrkA PF06798.12 CEH13310.1 - 0.0084 15.8 0.1 0.0096 15.6 0.1 1.1 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain BicD PF09730.9 CEH13310.1 - 0.0095 14.4 0.2 0.0099 14.4 0.2 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D TBCA PF02970.16 CEH13310.1 - 0.014 15.7 0.4 0.02 15.2 0.4 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor A PSCyt2 PF07583.11 CEH13310.1 - 0.095 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) UPF0242 PF06785.11 CEH13310.1 - 0.15 12.1 4.2 0.17 12.0 4.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2570 PF10828.8 CEH13311.1 - 1.2 9.0 3.6 6.2 6.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Oxysterol_BP PF01237.18 CEH13312.1 - 0.11 11.3 2.4 0.16 10.8 2.4 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein PV-1 PF06637.11 CEH13312.1 - 0.28 10.0 5.2 0.44 9.3 5.2 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Pyr_redox_2 PF07992.14 CEH13314.1 - 1.8e-38 132.5 0.1 5.1e-38 131.0 0.2 1.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 CEH13314.1 - 6.3e-20 71.3 0.0 1.3e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.6 CEH13314.1 - 1.1e-12 47.7 0.0 2.6e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 CEH13314.1 - 1.7e-12 47.5 4.8 1.4e-10 41.3 3.9 2.7 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.27 CEH13314.1 - 1.5e-11 44.7 0.7 1.5e-11 44.7 0.7 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 CEH13314.1 - 1.3e-09 37.9 0.0 7.7e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 CEH13314.1 - 1.2e-08 34.7 0.0 2.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain NAD_binding_9 PF13454.6 CEH13314.1 - 0.0036 17.3 1.3 6.1 6.8 0.0 3.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding Rubredoxin_C PF18267.1 CEH13314.1 - 0.011 15.7 0.1 8.5 6.4 0.0 2.7 2 0 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain K_oxygenase PF13434.6 CEH13314.1 - 0.094 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CEH13314.1 - 0.14 11.4 0.0 9.1 5.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 CEH13314.1 - 0.26 11.6 2.2 13 6.1 0.2 2.4 2 0 0 2 2 2 0 TrkA-N domain Oxidored_molyb PF00174.19 CEH13315.1 - 2.3e-56 190.1 0.0 5.7e-56 188.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CEH13315.1 - 7.1e-47 158.9 0.1 1.4e-46 157.9 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 CEH13315.1 - 3.5e-24 85.0 0.0 2.7e-23 82.2 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CEH13315.1 - 2.6e-23 82.8 0.0 8.3e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 CEH13315.1 - 2.5e-19 69.2 0.1 5.6e-19 68.1 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 CEH13315.1 - 0.0021 18.2 0.0 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF5102 PF17104.5 CEH13316.1 - 1.4e-46 159.8 0.0 2.6e-46 159.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) MCU PF04678.13 CEH13317.1 - 0.019 15.1 2.0 0.03 14.4 2.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Lebercilin PF15619.6 CEH13317.1 - 0.053 13.2 9.2 0.074 12.7 9.2 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 CEH13317.1 - 0.083 11.8 10.7 0.12 11.3 10.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 CEH13317.1 - 0.11 12.6 0.3 0.11 12.6 0.3 2.9 2 1 0 2 2 2 0 bZIP transcription factor TryThrA_C PF12319.8 CEH13317.1 - 1.1 8.7 10.4 0.063 12.8 4.3 1.9 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Shugoshin_N PF07558.11 CEH13317.1 - 1.5 8.8 5.0 0.34 10.8 0.8 2.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region HalX PF08663.10 CEH13317.1 - 3.3 8.1 5.7 1.4 9.3 1.3 2.2 1 1 0 2 2 2 0 HalX domain ATG16 PF08614.11 CEH13319.1 - 0.01 16.1 4.5 0.019 15.2 4.0 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FPP PF05911.11 CEH13319.1 - 0.015 13.5 2.7 0.02 13.1 2.7 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil BLOC1_2 PF10046.9 CEH13319.1 - 0.063 13.6 0.7 0.15 12.4 0.7 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 CEH13319.1 - 0.088 12.9 1.7 0.14 12.2 1.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ribosomal_S5 PF00333.20 CEH13321.1 - 1.8e-28 98.3 1.5 3.5e-28 97.4 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CEH13321.1 - 7.9e-22 76.5 0.1 1.5e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S10 PF00338.22 CEH13322.1 - 4.8e-27 94.1 0.3 5.6e-27 93.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GFA PF04828.14 CEH13323.1 - 0.003 17.9 1.7 1.2 9.5 0.1 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Zn_Tnp_IS1595 PF12760.7 CEH13323.1 - 0.003 17.5 8.1 0.24 11.4 0.6 2.2 1 1 1 2 2 2 2 Transposase zinc-ribbon domain zf-CCHC_2 PF13696.6 CEH13323.1 - 0.018 14.9 3.9 2.6 8.0 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-C4pol PF14260.6 CEH13323.1 - 0.022 15.2 1.1 0.057 13.9 1.1 1.6 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta UPF0167 PF03691.14 CEH13323.1 - 0.024 14.4 0.1 4.4 7.1 0.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) Gmx_para_CXXCG PF09535.10 CEH13323.1 - 0.039 13.2 1.2 2.3 7.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) DZR PF12773.7 CEH13323.1 - 0.056 13.5 4.5 0.092 12.8 3.6 1.8 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L40e PF01020.17 CEH13323.1 - 0.06 13.2 4.1 3.5 7.6 0.2 2.5 2 0 0 2 2 2 0 Ribosomal L40e family DUF2845 PF11006.8 CEH13323.1 - 0.061 13.4 1.3 5 7.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2845) zf_C2H2_13 PF18508.1 CEH13323.1 - 0.068 12.8 7.1 1.4 8.6 0.4 2.3 2 0 0 2 2 2 0 Zinc finger domain zf-ribbon_3 PF13248.6 CEH13323.1 - 0.12 11.8 1.1 9.7 5.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HTH_23 PF13384.6 CEH13323.1 - 0.13 12.1 0.8 6.9 6.6 0.1 2.4 2 1 1 3 3 3 0 Homeodomain-like domain Peptidase_C98 PF15499.6 CEH13323.1 - 0.13 11.7 0.4 13 5.2 0.1 1.9 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2688 PF10892.8 CEH13323.1 - 0.18 11.3 7.0 2.3 7.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) zf-RRN7 PF11781.8 CEH13323.1 - 0.28 10.9 6.6 4.7 7.0 0.7 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-RanBP PF00641.18 CEH13323.1 - 0.29 10.5 3.4 8.8 5.7 0.2 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others ribosomal_L24 PF17136.4 CEH13323.1 - 0.38 11.2 2.3 2.3 8.6 2.5 2.0 1 1 1 2 2 2 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 DUF5538 PF17692.1 CEH13323.1 - 0.4 10.7 4.7 2.6 8.1 0.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5538) PDCD2_C PF04194.13 CEH13323.1 - 1.4 8.9 3.1 15 5.6 0.3 2.0 1 1 1 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain zf-CCHC PF00098.23 CEH13323.1 - 3.5 7.9 10.0 5.7 7.2 0.2 2.9 4 0 0 4 4 2 0 Zinc knuckle RNA_POL_M_15KD PF02150.16 CEH13323.1 - 3.6 7.5 4.8 20 5.2 0.5 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit CBFD_NFYB_HMF PF00808.23 CEH13324.1 - 2.9e-18 65.9 0.8 4.2e-18 65.4 0.8 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEH13324.1 - 4.5e-13 49.7 0.2 4.5e-13 49.7 0.2 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DnaJ PF00226.31 CEH13325.1 - 3.8e-17 62.2 0.1 7e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain Sec3_C PF09763.9 CEH13325.1 - 0.21 9.9 1.4 0.29 9.5 1.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF1682 PF07946.14 CEH13325.1 - 0.86 8.8 7.9 1.2 8.2 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) P21-Arc PF04062.14 CEH13326.1 - 1.1e-76 256.7 0.0 1.2e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit HA2 PF04408.23 CEH13327.1 - 1.5e-21 76.7 0.2 1.2e-20 73.8 0.0 2.7 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEH13327.1 - 1.7e-16 60.4 0.0 3.3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEH13327.1 - 5.3e-13 49.3 0.0 1.6e-12 47.7 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEH13327.1 - 8.3e-08 32.2 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEH13327.1 - 2.5e-05 24.6 0.1 7.2e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEH13327.1 - 0.0004 20.2 0.0 0.0015 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CEH13327.1 - 0.0094 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CEH13327.1 - 0.016 15.4 0.1 0.081 13.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 CEH13327.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 CEH13327.1 - 0.018 15.4 0.1 0.04 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CEH13327.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 CEH13327.1 - 0.039 13.5 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 CEH13327.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 CEH13327.1 - 0.047 14.2 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 CEH13327.1 - 0.052 13.1 0.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 CEH13327.1 - 0.058 13.5 0.1 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 CEH13327.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 CEH13327.1 - 0.066 13.2 0.0 0.39 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CEH13327.1 - 0.092 12.2 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 CEH13327.1 - 0.13 12.6 0.0 0.13 12.6 0.0 2.9 3 1 0 3 3 1 0 AAA ATPase domain Myosin_head PF00063.21 CEH13327.1 - 0.23 9.6 0.0 0.35 9.0 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Nop14 PF04147.12 CEH13328.1 - 1.9e-258 860.2 0.5 2.6e-258 859.8 0.5 1.1 1 0 0 1 1 1 1 Nop14-like family Proteasome PF00227.26 CEH13329.1 - 2.1e-34 118.6 0.0 2.6e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SAMP PF05924.11 CEH13329.1 - 0.02 14.2 0.7 0.034 13.5 0.7 1.3 1 0 0 1 1 1 0 SAMP Motif PIG-P PF08510.12 CEH13330.1 - 1.1e-27 96.3 0.0 1.5e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 CEH13330.1 - 0.014 15.6 4.5 0.028 14.7 4.5 1.4 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Per1 PF04080.13 CEH13330.1 - 0.18 11.5 0.9 0.24 11.1 0.9 1.1 1 0 0 1 1 1 0 Per1-like family Pyr_redox_2 PF07992.14 CEH13331.1 - 1.2e-64 218.4 8.3 1.9e-64 217.7 8.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEH13331.1 - 3.8e-39 133.4 0.1 9e-39 132.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CEH13331.1 - 2.8e-19 69.5 7.1 1.6e-16 60.6 1.5 3.3 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEH13331.1 - 5.9e-11 42.4 0.6 5.9e-11 42.4 0.6 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CEH13331.1 - 8.8e-11 41.6 3.6 4.1e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEH13331.1 - 6.6e-08 32.7 3.4 0.00051 20.2 0.5 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CEH13331.1 - 1.1e-06 28.1 2.1 1.1e-06 28.1 2.1 2.9 4 0 0 4 4 4 1 FAD binding domain GIDA PF01134.22 CEH13331.1 - 1.4e-06 27.7 14.0 3.6e-06 26.3 5.2 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CEH13331.1 - 2.6e-06 26.9 6.6 0.0049 16.2 0.6 2.9 2 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CEH13331.1 - 2.2e-05 23.8 2.0 0.00074 18.8 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 CEH13331.1 - 7.9e-05 21.5 12.1 0.00077 18.3 0.8 4.0 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 CEH13331.1 - 0.00012 21.4 0.1 0.48 9.5 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 CEH13331.1 - 0.0027 17.0 9.8 0.11 11.8 0.8 3.2 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 CEH13331.1 - 0.32 10.0 1.4 2.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 CEH13331.1 - 0.42 11.1 4.2 0.42 11.1 0.2 2.8 3 0 0 3 3 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 CEH13331.1 - 2.2 8.1 5.7 0.33 10.8 0.7 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 CEH13332.1 - 5.9e-10 38.6 25.2 1.2e-09 37.6 16.9 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CEH13332.1 - 3.6e-05 22.5 0.4 3.6e-05 22.5 0.4 2.6 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 CEH13332.1 - 0.047 12.5 0.0 0.074 11.9 0.0 1.4 1 0 0 1 1 1 0 MFS_1 like family Pol_alpha_B_N PF08418.10 CEH13333.1 - 3.2e-32 112.5 0.0 5e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 CEH13333.1 - 5.8e-30 104.2 0.1 8.6e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Na_Ca_ex PF01699.24 CEH13334.1 - 4.8e-45 153.2 42.0 1.1e-26 93.6 16.1 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Zip PF02535.22 CEH13334.1 - 0.00084 18.6 4.9 0.07 12.3 5.5 2.6 2 0 0 2 2 2 1 ZIP Zinc transporter Sec10 PF07393.11 CEH13334.1 - 0.26 9.6 3.6 0.37 9.1 3.6 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Trypan_PARP PF05887.11 CEH13334.1 - 0.28 11.1 15.1 0.059 13.3 10.2 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Macoilin PF09726.9 CEH13334.1 - 4.2 5.8 10.5 7.2 5.0 10.5 1.2 1 0 0 1 1 1 0 Macoilin family Dicty_REP PF05086.12 CEH13334.1 - 5.3 4.9 6.1 7.5 4.4 6.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DEAD PF00270.29 CEH13335.1 - 2.4e-46 157.7 0.0 4.1e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH13335.1 - 2.2e-30 105.2 0.0 6.4e-30 103.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH13335.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_L18A PF01775.17 CEH13336.1 - 3.4e-54 182.1 0.2 4.2e-54 181.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Cpn60_TCP1 PF00118.24 CEH13337.1 - 1.2e-150 502.4 11.6 1.5e-150 502.1 11.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 CEH13337.1 - 0.0003 20.4 0.1 0.00081 18.9 0.0 1.7 2 0 0 2 2 2 1 Telomere recombination dCMP_cyt_deam_1 PF00383.23 CEH13338.1 - 1e-24 86.3 0.6 2e-24 85.4 0.6 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEH13338.1 - 1.6e-09 37.6 0.1 4.7e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 MafB19-like deaminase APOBEC4_like PF18774.1 CEH13338.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase SNAD4 PF18750.1 CEH13338.1 - 0.026 14.6 0.1 0.055 13.6 0.1 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 AAA_18 PF13238.6 CEH13338.1 - 0.048 14.2 0.0 0.091 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEH13338.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEH13338.1 - 0.087 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L1 PF00687.21 CEH13339.1 - 1.3e-44 152.4 2.1 1.7e-44 152.0 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L23eN PF03939.13 CEH13340.1 - 4.8e-22 77.9 11.4 4.8e-22 77.9 11.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CEH13340.1 - 6.5e-14 52.1 2.4 4.9e-13 49.3 0.6 2.4 2 1 0 2 2 2 1 Ribosomal protein L23 TusA PF01206.17 CEH13340.1 - 0.015 15.1 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Sulfurtransferase TusA DASH_Dam1 PF08653.10 CEH13341.1 - 8.8e-21 73.5 0.2 1.4e-20 72.8 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 Ribosomal_L37ae PF01780.19 CEH13342.1 - 8.6e-43 144.3 9.3 9.6e-43 144.2 9.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 CEH13342.1 - 0.0027 17.6 3.3 0.0046 16.9 3.3 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 CEH13342.1 - 0.004 17.2 0.6 0.0054 16.8 0.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-BED PF02892.15 CEH13342.1 - 0.014 15.5 4.7 0.43 10.7 0.3 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 CEH13342.1 - 0.049 14.1 5.3 1.9 9.0 0.9 2.2 1 1 1 2 2 2 0 Zinc-finger double domain C1_2 PF03107.16 CEH13342.1 - 0.62 10.4 3.6 1.9 8.9 3.7 1.7 1 1 0 1 1 1 0 C1 domain DUF2235 PF09994.9 CEH13344.1 - 1.4e-60 205.2 0.0 2.1e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) HSF_DNA-bind PF00447.17 CEH13345.1 - 1.6e-19 70.3 0.0 2.5e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Adaptin_N PF01602.20 CEH13348.1 - 5.1e-95 319.0 5.9 6.5e-68 229.6 6.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 CEH13348.1 - 3.9e-56 188.5 0.0 1.1e-55 187.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CEH13348.1 - 1.9e-55 186.6 0.1 4.5e-55 185.4 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 CEH13348.1 - 9.1e-11 42.1 2.8 0.0046 17.0 0.0 4.7 1 1 3 4 4 4 4 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEH13348.1 - 1.1e-08 35.3 9.2 0.031 14.6 0.2 6.0 3 1 3 6 6 6 4 HEAT repeats HEAT PF02985.22 CEH13348.1 - 3.6e-08 33.0 0.3 0.037 14.3 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat DUF5578 PF17741.1 CEH13348.1 - 0.0071 15.8 4.0 0.18 11.2 1.4 2.9 2 0 0 2 2 2 1 Family of unknown function (DUF5578) RTP1_C1 PF10363.9 CEH13348.1 - 0.02 15.0 5.0 1.7 8.8 0.0 3.6 3 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF5071 PF16804.5 CEH13348.1 - 0.024 14.9 0.1 11 6.3 0.0 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF5071) PaaB PF06243.11 CEH13348.1 - 0.061 13.6 0.2 0.19 11.9 0.1 1.9 2 0 0 2 2 2 0 Phenylacetic acid degradation B Ribosomal_L16 PF00252.18 CEH13350.1 - 2.1e-41 141.0 0.0 2.7e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PCI PF01399.27 CEH13352.1 - 0.064 13.8 0.0 0.22 12.1 0.0 1.9 2 0 0 2 2 2 0 PCI domain AAA PF00004.29 CEH13353.1 - 8.1e-44 149.2 0.0 1.4e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEH13353.1 - 1.5e-10 40.7 0.1 3.5e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CEH13353.1 - 3.9e-08 33.1 0.5 9.2e-08 31.9 0.5 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CEH13353.1 - 1.2e-07 32.0 0.0 2.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CEH13353.1 - 3.5e-06 27.0 0.0 1.5e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEH13353.1 - 6e-06 26.7 0.1 6.1e-05 23.5 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEH13353.1 - 2.9e-05 24.4 0.1 0.0052 17.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CEH13353.1 - 9e-05 22.3 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CEH13353.1 - 0.0013 18.0 0.0 0.0027 17.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CEH13353.1 - 0.0017 18.5 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEH13353.1 - 0.0025 17.6 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CEH13353.1 - 0.0037 17.8 0.0 0.023 15.2 0.0 2.3 3 0 0 3 3 2 1 AAA domain PhoH PF02562.16 CEH13353.1 - 0.0046 16.4 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 CEH13353.1 - 0.0074 15.7 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CEH13353.1 - 0.0087 15.8 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 CEH13353.1 - 0.0093 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CEH13353.1 - 0.011 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CEH13353.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 CEH13353.1 - 0.023 14.1 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 CEH13353.1 - 0.028 14.1 0.1 0.11 12.1 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.13 CEH13353.1 - 0.031 13.4 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CEH13353.1 - 0.042 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CEH13353.1 - 0.044 14.2 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.9 CEH13353.1 - 0.047 14.0 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_14 PF13173.6 CEH13353.1 - 0.053 13.6 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CEH13353.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CEH13353.1 - 0.075 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RILP PF11461.8 CEH13353.1 - 0.082 13.1 1.1 0.16 12.2 1.1 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein Zeta_toxin PF06414.12 CEH13353.1 - 0.094 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 CEH13353.1 - 0.099 13.0 0.1 0.48 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CEH13353.1 - 0.13 12.0 0.0 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cnd3 PF12719.7 CEH13354.1 - 2.3e-64 217.4 0.2 5.9e-64 216.1 0.0 1.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Anti-adapt_IraP PF10796.9 CEH13354.1 - 0.095 13.3 0.0 0.53 10.9 0.0 2.3 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein HEAT PF02985.22 CEH13354.1 - 0.11 12.8 1.5 7.9 7.0 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 CEH13354.1 - 0.2 12.0 8.3 0.35 11.3 0.1 4.3 5 0 0 5 5 5 0 HEAT repeats ORC6 PF05460.13 CEH13354.1 - 0.93 8.7 5.9 2 7.6 5.9 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pcc1 PF09341.10 CEH13355.1 - 9.5e-17 60.9 0.7 1.2e-16 60.6 0.7 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 ABC_tran PF00005.27 CEH13356.1 - 3.5e-33 115.0 0.1 2e-16 60.7 0.0 3.1 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 CEH13356.1 - 2.1e-12 46.6 5.8 2.1e-12 46.6 5.8 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 CEH13356.1 - 2.4e-11 43.5 4.7 0.0015 18.0 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CEH13356.1 - 3e-07 30.5 5.0 0.22 11.3 0.9 4.0 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CEH13356.1 - 3.3e-06 27.1 0.1 0.088 12.5 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 CEH13356.1 - 6.6e-06 26.6 0.0 0.022 15.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CEH13356.1 - 8.2e-06 25.8 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CEH13356.1 - 7.1e-05 23.1 0.0 0.027 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEH13356.1 - 8.9e-05 22.9 0.0 0.036 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CEH13356.1 - 0.00016 21.3 0.3 0.52 10.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 CEH13356.1 - 0.00064 19.7 0.0 0.5 10.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4 PF00037.27 CEH13356.1 - 0.00069 19.3 4.0 0.00069 19.3 4.0 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain NACHT PF05729.12 CEH13356.1 - 0.0013 18.7 0.9 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 CEH13356.1 - 0.0014 18.2 0.0 0.023 14.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region TniB PF05621.11 CEH13356.1 - 0.0015 18.0 0.0 0.095 12.1 0.0 2.7 3 0 0 3 3 3 1 Bacterial TniB protein RNA_helicase PF00910.22 CEH13356.1 - 0.0018 18.6 0.0 0.59 10.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 CEH13356.1 - 0.0027 17.5 0.3 0.82 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 CEH13356.1 - 0.0027 18.3 7.9 0.0074 16.9 0.3 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_23 PF13476.6 CEH13356.1 - 0.0029 18.1 2.5 0.076 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 CEH13356.1 - 0.003 17.6 11.4 0.0067 16.5 11.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_33 PF13671.6 CEH13356.1 - 0.0034 17.6 0.0 0.95 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CEH13356.1 - 0.0055 16.4 1.6 0.63 9.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 CEH13356.1 - 0.0062 15.8 0.0 0.37 9.9 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain TsaE PF02367.17 CEH13356.1 - 0.0071 16.3 0.1 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_6 PF12837.7 CEH13356.1 - 0.0087 16.1 3.1 0.0087 16.1 3.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain SbcCD_C PF13558.6 CEH13356.1 - 0.014 15.6 0.0 5.9 7.2 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 CEH13356.1 - 0.019 15.2 0.1 7.5 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CEH13356.1 - 0.025 14.6 1.1 22 5.1 0.0 4.1 4 1 1 5 5 5 0 AAA domain VirE PF05272.11 CEH13356.1 - 0.025 14.3 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_16 PF13484.6 CEH13356.1 - 0.033 15.1 0.3 0.033 15.1 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_18 PF13238.6 CEH13356.1 - 0.035 14.7 0.0 6.1 7.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 CEH13356.1 - 0.064 13.4 11.3 0.16 12.2 11.3 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.6 CEH13356.1 - 0.065 12.9 0.8 3.2 7.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 CEH13356.1 - 0.077 12.7 0.2 11 5.7 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase Fer4_10 PF13237.6 CEH13356.1 - 0.083 13.0 16.3 0.08 13.1 2.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Septin PF00735.18 CEH13356.1 - 0.14 11.5 0.1 4.7 6.4 0.0 2.5 2 1 1 3 3 3 0 Septin AAA_5 PF07728.14 CEH13356.1 - 0.14 12.2 1.6 2.4 8.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Fer4_8 PF13183.6 CEH13356.1 - 0.36 11.3 5.7 0.44 11.0 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Cyclin PF08613.11 CEH13357.1 - 1e-06 29.2 2.4 1e-05 26.0 0.0 2.8 3 0 0 3 3 3 1 Cyclin SAD_SRA PF02182.17 CEH13358.1 - 4.7e-32 110.8 0.0 7e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain REV PF00424.18 CEH13358.1 - 0.068 13.2 4.1 1.5 8.9 0.6 2.8 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) Ribosomal_L3 PF00297.22 CEH13360.1 - 1.9e-177 589.8 7.2 2.2e-177 589.6 7.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 MerB PF03243.15 CEH13361.1 - 0.049 13.8 0.0 0.056 13.6 0.0 1.0 1 0 0 1 1 1 0 Alkylmercury lyase Gly_transf_sug PF04488.15 CEH13362.1 - 8.6e-21 74.4 0.0 1.5e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Polysacc_deac_3 PF15421.6 CEH13362.1 - 0.084 11.4 0.1 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase Histone_H2A_C PF16211.5 CEH13364.1 - 1.8e-17 62.8 2.5 3.4e-17 61.9 2.5 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CEH13364.1 - 2.1e-17 63.7 0.0 2.7e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CEH13364.1 - 9.1e-06 25.9 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEH13365.1 - 3.2e-22 79.3 2.9 4.3e-22 78.9 2.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CEH13365.1 - 1.4e-06 28.5 0.1 3.2e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CEH13365.1 - 0.00028 21.3 0.0 0.00051 20.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 CEH13365.1 - 0.033 13.8 1.3 1.4 8.5 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain CENP-W PF15510.6 CEH13365.1 - 0.055 13.7 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein YscO-like PF16789.5 CEH13365.1 - 0.067 13.2 0.5 0.085 12.9 0.5 1.1 1 0 0 1 1 1 0 YscO-like protein Complex1_LYR PF05347.15 CEH13366.1 - 5.7e-07 29.5 0.4 1.1e-06 28.5 0.4 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CEH13366.1 - 0.00026 21.7 0.3 0.00063 20.4 0.3 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Ribosomal_L16 PF00252.18 CEH13367.1 - 8e-15 55.0 0.1 3.3e-08 33.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein L16p/L10e zf-ZPR1 PF03367.13 CEH13368.1 - 2.7e-109 362.1 0.0 6.2e-54 182.1 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Lar_restr_allev PF14354.6 CEH13368.1 - 0.02 15.3 0.2 11 6.5 0.1 2.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 CEH13368.1 - 0.12 12.4 2.7 5.2 7.2 0.1 3.1 3 0 0 3 3 3 0 Double zinc ribbon Tim17 PF02466.19 CEH13369.1 - 9.7e-22 77.5 6.6 1.6e-21 76.7 6.6 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_S8e PF01201.22 CEH13371.1 - 2.7e-36 124.8 4.5 4.3e-36 124.1 4.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e Gpr1_Fun34_YaaH PF01184.19 CEH13373.1 - 2.9e-50 170.8 20.5 3.7e-50 170.4 20.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family AAA PF00004.29 CEH13374.1 - 1.3e-90 300.6 0.0 1.1e-46 158.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEH13374.1 - 6.1e-21 74.0 1.1 5.2e-10 39.0 0.1 2.9 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CEH13374.1 - 2.9e-14 53.1 0.0 2.6e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CEH13374.1 - 1.2e-12 48.6 3.7 0.0038 17.6 0.0 5.2 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 CEH13374.1 - 5.9e-11 42.5 0.7 0.00054 20.0 0.2 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEH13374.1 - 9e-11 42.2 1.7 0.033 14.5 0.0 4.8 2 2 2 4 4 4 2 AAA domain AAA_2 PF07724.14 CEH13374.1 - 1.8e-10 41.2 0.0 0.0011 19.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CEH13374.1 - 4.7e-09 36.6 0.0 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CEH13374.1 - 1.4e-07 31.1 0.3 0.0046 16.2 0.0 2.9 2 1 1 3 3 3 2 TIP49 P-loop domain Mg_chelatase PF01078.21 CEH13374.1 - 7e-07 28.8 0.5 0.035 13.5 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CEH13374.1 - 2e-06 27.9 0.0 0.041 13.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CEH13374.1 - 2.8e-06 27.7 0.0 0.075 13.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 CEH13374.1 - 2.2e-05 24.5 1.1 0.08 12.8 0.0 3.8 3 1 1 4 4 4 1 NACHT domain AAA_3 PF07726.11 CEH13374.1 - 2.2e-05 24.3 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CEH13374.1 - 2.5e-05 24.1 0.5 0.14 11.9 0.0 2.5 2 1 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 CEH13374.1 - 7.3e-05 22.8 0.0 0.3 11.0 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain Cytidylate_kin2 PF13189.6 CEH13374.1 - 8.3e-05 22.8 0.0 0.078 13.1 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.27 CEH13374.1 - 0.00013 22.5 0.0 0.2 12.2 0.0 2.7 2 0 0 2 2 2 1 ABC transporter ATPase PF06745.13 CEH13374.1 - 0.0002 20.8 0.1 3.5 6.9 0.0 3.3 3 0 0 3 3 3 1 KaiC AAA_18 PF13238.6 CEH13374.1 - 0.0002 21.9 0.0 0.24 11.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CEH13374.1 - 0.00023 21.0 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CEH13374.1 - 0.00025 20.8 0.0 0.26 11.0 0.0 3.4 3 1 0 3 3 3 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 CEH13374.1 - 0.00025 21.2 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 CEH13374.1 - 0.00026 20.5 0.0 0.29 10.6 0.0 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 CEH13374.1 - 0.00051 19.7 3.9 0.94 9.0 0.1 4.0 3 1 2 5 5 5 2 AAA domain AAA_28 PF13521.6 CEH13374.1 - 0.00064 20.0 0.0 0.89 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CEH13374.1 - 0.0007 19.6 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 CEH13374.1 - 0.00086 19.7 0.3 1.8 9.0 0.1 2.7 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 CEH13374.1 - 0.0011 18.3 0.1 0.61 9.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Vps4_C PF09336.10 CEH13374.1 - 0.002 18.1 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.18 CEH13374.1 - 0.0026 17.5 0.0 0.98 9.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CEH13374.1 - 0.0027 16.9 0.0 0.03 13.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 CEH13374.1 - 0.0047 16.2 0.1 3 6.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TniB PF05621.11 CEH13374.1 - 0.0092 15.4 0.0 21 4.5 0.0 3.5 4 0 0 4 4 3 0 Bacterial TniB protein AAA_24 PF13479.6 CEH13374.1 - 0.012 15.4 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 CEH13374.1 - 0.014 14.3 0.0 0.77 8.6 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase PhoH PF02562.16 CEH13374.1 - 0.026 14.0 0.5 7.5 5.9 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein SKI PF01202.22 CEH13374.1 - 0.029 14.5 0.1 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase ATPase_2 PF01637.18 CEH13374.1 - 0.04 13.8 0.1 8 6.3 0.0 3.0 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CEH13374.1 - 0.041 14.2 1.9 3.3 8.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CEH13374.1 - 0.058 13.1 3.0 10 5.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 CEH13374.1 - 0.077 12.1 0.0 7.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.15 CEH13374.1 - 0.25 11.3 0.0 16 5.3 0.0 2.5 2 0 0 2 2 2 0 NTPase PUB PF09409.10 CEH13375.1 - 2.3e-10 40.3 0.0 4.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 PUB domain Thioredoxin_4 PF13462.6 CEH13375.1 - 1.4 9.1 5.1 0.36 11.0 0.3 2.2 2 1 0 2 2 2 0 Thioredoxin Folliculin PF11704.8 CEH13375.1 - 4.1 7.2 6.4 1.3 8.9 1.9 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport EamA PF00892.20 CEH13376.1 - 2.4e-06 27.8 25.3 9e-06 25.9 4.8 3.3 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 CEH13376.1 - 0.0013 18.3 6.6 0.0046 16.5 1.7 2.2 2 0 0 2 2 2 2 Solute carrier family 35 DUF3955 PF13127.6 CEH13376.1 - 0.0029 17.4 2.9 0.0029 17.4 2.9 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3955) PgpA PF04608.13 CEH13376.1 - 0.26 11.3 3.8 0.12 12.4 0.7 2.0 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A DUF1003 PF06210.11 CEH13376.1 - 1.6 8.8 4.3 0.51 10.5 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) CX9C PF16860.5 CEH13377.1 - 7.2e-05 22.7 3.9 0.0076 16.2 1.2 2.1 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 CEH13377.1 - 0.00021 21.4 3.5 0.00042 20.5 3.5 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.13 CEH13377.1 - 0.0037 17.4 3.2 0.042 14.0 3.0 2.0 1 1 1 2 2 2 1 CHCH domain Cmc1 PF08583.10 CEH13377.1 - 0.011 15.7 2.8 1.7 8.7 1.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 CEH13377.1 - 0.018 15.4 0.9 0.026 14.9 0.9 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.8 CEH13377.1 - 0.026 14.9 3.1 0.062 13.7 3.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) SNAP PF14938.6 CEH13378.1 - 2.1e-88 296.4 12.3 2.4e-88 296.2 12.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CEH13378.1 - 1.9e-06 28.1 5.0 0.017 15.4 3.3 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEH13378.1 - 0.0083 16.2 6.2 4.6 7.6 0.1 5.4 2 2 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEH13378.1 - 0.026 14.3 3.0 7.8 6.5 0.2 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 CEH13378.1 - 0.032 13.3 2.7 0.16 11.0 0.1 2.1 2 0 0 2 2 2 0 Spatacsin C-terminus TPR_7 PF13176.6 CEH13378.1 - 0.04 14.0 5.8 2.7 8.2 0.3 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4810 PF16068.5 CEH13378.1 - 0.056 14.0 0.6 0.24 12.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) SNF2_N PF00176.23 CEH13379.1 - 1.1e-72 244.7 0.2 2.6e-72 243.5 0.2 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEH13379.1 - 3.1e-22 79.0 0.1 4.3e-19 68.9 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 CEH13379.1 - 5.6e-20 71.4 7.8 5.6e-20 71.4 7.8 3.6 3 0 0 3 3 3 1 HSA Bromodomain PF00439.25 CEH13379.1 - 1.3e-14 54.0 0.1 3.8e-14 52.5 0.1 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 CEH13379.1 - 5.2e-12 46.2 0.9 5.2e-12 46.2 0.9 3.3 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 CEH13379.1 - 1.1e-10 41.1 0.1 1.1e-10 41.1 0.1 3.6 3 0 0 3 3 3 1 QLQ ResIII PF04851.15 CEH13379.1 - 6.1e-09 36.1 0.0 2.5e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TCL1_MTCP1 PF01840.17 CEH13379.1 - 0.067 12.9 0.1 0.26 11.0 0.1 1.9 1 0 0 1 1 1 0 TCL1/MTCP1 family DBINO PF13892.6 CEH13379.1 - 2 8.8 15.2 9.4 6.6 14.9 2.4 1 1 0 1 1 1 0 DNA-binding domain 2-Hacid_dh_C PF02826.19 CEH13381.1 - 4.7e-28 97.7 0.0 1.1e-27 96.6 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CEH13381.1 - 5.3e-05 23.3 0.0 8.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 CEH13381.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CEH13381.1 - 0.0035 17.7 0.0 0.0065 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding XdhC_C PF13478.6 CEH13381.1 - 0.015 15.8 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Fumerase_C PF05683.12 CEH13382.1 - 0.052 12.9 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 Fumarase C-terminus PVL_ORF50 PF07768.11 CEH13383.1 - 0.26 11.6 2.6 0.62 10.4 2.6 1.6 1 0 0 1 1 1 0 PVL ORF-50-like family adh_short_C2 PF13561.6 CEH13384.1 - 9.6e-32 110.4 0.0 1.4e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH13384.1 - 1.3e-21 76.9 0.0 1.8e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH13384.1 - 0.00045 20.2 0.1 0.0014 18.5 0.0 1.8 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 CEH13384.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 CEH13384.1 - 0.014 15.8 0.0 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding P_proprotein PF01483.20 CEH13384.1 - 0.049 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Proprotein convertase P-domain Citrate_bind PF16114.5 CEH13386.1 - 3.4e-88 293.8 0.1 6.4e-88 292.9 0.1 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 CEH13386.1 - 9e-19 67.8 0.0 7.3e-16 58.2 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 CEH13386.1 - 7e-15 55.2 0.1 1.3e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 CEH13386.1 - 1.1e-11 45.2 0.0 2.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 CEH13386.1 - 1.6e-07 31.1 0.0 3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 CEH13386.1 - 3.5e-06 26.8 0.0 9.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.6 CEH13386.1 - 0.11 11.9 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain Frag1 PF10277.9 CEH13387.1 - 9.8e-39 133.1 16.5 1.1e-38 132.9 16.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Pox_A14 PF05767.12 CEH13387.1 - 0.16 12.1 7.9 0.034 14.3 3.4 2.1 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 Gate PF07670.14 CEH13387.1 - 0.18 12.1 6.5 0.028 14.7 1.9 2.0 2 1 0 2 2 2 0 Nucleoside recognition Yip1 PF04893.17 CEH13387.1 - 0.2 11.3 13.1 0.062 13.0 8.0 2.3 1 1 1 2 2 2 0 Yip1 domain Cation_ATPase_C PF00689.21 CEH13387.1 - 0.25 11.0 13.4 0.88 9.3 2.8 2.3 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Phage_holin_3_6 PF07332.11 CEH13387.1 - 1.2 9.3 15.5 1.4 9.0 3.1 3.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SUR7 PF06687.12 CEH13387.1 - 7 6.2 15.9 7.1 6.2 4.6 2.9 1 1 1 2 2 2 0 SUR7/PalI family E1_dh PF00676.20 CEH13388.1 - 1.2e-111 372.4 0.1 1.5e-111 372.2 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CEH13388.1 - 0.00014 21.2 0.1 0.00027 20.3 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 CEH13388.1 - 0.0031 17.3 1.4 0.0031 17.3 1.4 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DIM PF08194.12 CEH13390.1 - 0.0017 18.5 0.7 0.0029 17.8 0.7 1.3 1 0 0 1 1 1 1 DIM protein GTP_cyclohydroI PF01227.22 CEH13391.1 - 1.6e-73 245.9 0.3 2.3e-73 245.4 0.3 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CEH13391.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein HATPase_c_2 PF13581.6 CEH13391.1 - 0.044 13.8 0.2 0.097 12.6 0.2 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MFS_1 PF07690.16 CEH13392.1 - 4.5e-34 117.9 41.7 6.7e-34 117.3 41.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily 2-oxoacid_dh PF00198.23 CEH13393.1 - 4.6e-77 258.6 0.0 6e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CEH13393.1 - 7e-19 67.4 0.7 2e-18 66.0 0.7 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CEH13393.1 - 8.8e-17 61.2 0.9 3e-16 59.5 0.9 2.0 1 0 0 1 1 1 1 e3 binding domain SspB PF04386.13 CEH13393.1 - 5.2 6.9 8.3 11 5.8 0.0 2.6 2 1 1 3 3 3 0 Stringent starvation protein B AMPK1_CBM PF16561.5 CEH13394.1 - 2.1e-25 88.7 0.0 3.5e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CEH13394.1 - 1.7e-13 50.7 0.1 1.7e-13 50.7 0.1 1.9 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Ndc80_HEC PF03801.13 CEH13395.1 - 2.2e-29 102.1 0.0 4.5e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 CEH13395.1 - 3.4e-12 46.3 11.3 6.1e-12 45.4 4.9 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF5595) Cytochrom_NNT PF03264.14 CEH13395.1 - 2.6 7.7 6.8 0.13 12.0 1.1 1.7 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region AAA_12 PF13087.6 CEH13396.1 - 1.7e-51 174.7 0.0 2.6e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEH13396.1 - 2.7e-50 171.6 0.0 5.7e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH13396.1 - 4.3e-15 56.3 0.1 3.2e-14 53.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEH13396.1 - 2e-12 47.2 0.2 1.1e-08 35.1 0.1 3.1 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CEH13396.1 - 2.2e-06 27.6 0.6 0.78 9.4 0.0 3.5 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CEH13396.1 - 2.1e-05 24.2 0.2 9.9e-05 22.0 0.0 2.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 CEH13396.1 - 0.0076 15.7 0.1 0.022 14.2 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 CEH13396.1 - 0.0079 16.2 0.0 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CEH13396.1 - 0.033 14.6 0.1 0.13 12.7 0.1 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CEH13396.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEH13396.1 - 0.14 12.4 0.0 0.7 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEH13397.1 - 1.1e-41 142.4 0.0 1.7e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CEH13397.1 - 2.7e-10 40.0 0.1 6e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CEH13397.1 - 5.1e-10 39.0 0.2 1.1e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CEH13397.1 - 4.8e-07 30.3 0.0 0.00023 21.6 0.0 2.9 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 CEH13397.1 - 5.4e-07 29.7 0.0 6.3e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CEH13397.1 - 2.6e-06 27.7 0.1 8.6e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CEH13397.1 - 6.4e-06 26.0 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEH13397.1 - 0.00023 21.5 0.1 0.0048 17.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 CEH13397.1 - 0.0024 18.4 0.0 0.0082 16.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.13 CEH13397.1 - 0.0028 16.9 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CEH13397.1 - 0.0039 16.6 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CEH13397.1 - 0.0048 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CEH13397.1 - 0.0048 16.1 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 CEH13397.1 - 0.0051 16.4 0.0 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 CEH13397.1 - 0.0073 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CEH13397.1 - 0.0077 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEH13397.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CEH13397.1 - 0.011 15.5 0.0 0.035 13.8 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CEH13397.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 CEH13397.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CEH13397.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CEH13397.1 - 0.026 13.9 0.1 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 CEH13397.1 - 0.033 13.6 0.1 0.06 12.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 CEH13397.1 - 0.033 14.4 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CEH13397.1 - 0.038 14.5 0.3 12 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CEH13397.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CEH13397.1 - 0.063 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CEH13397.1 - 0.074 12.6 0.4 0.19 11.2 0.1 1.8 2 0 0 2 2 1 0 AAA domain Prot_ATP_OB_N PF17758.1 CEH13397.1 - 0.083 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain CPT PF07931.12 CEH13397.1 - 0.094 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 CEH13397.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Ferritin_2 PF13668.6 CEH13398.1 - 3.6e-08 33.7 0.3 3.6e-08 33.7 0.3 2.0 3 0 0 3 3 3 1 Ferritin-like domain WD40_4 PF16300.5 CEH13399.1 - 1.6e-25 88.7 0.2 3.2e-12 46.1 0.1 2.7 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 CEH13399.1 - 2.6e-08 34.4 3.5 0.049 14.5 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH13399.1 - 8.8e-08 32.4 0.0 0.033 14.5 0.0 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 CEH13399.1 - 0.035 14.0 0.0 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) Spc24 PF08286.11 CEH13400.1 - 8.5e-07 29.2 1.9 0.00017 21.8 0.0 2.6 2 1 0 2 2 2 2 Spc24 subunit of Ndc80 APG6_N PF17675.1 CEH13400.1 - 0.0082 16.7 14.9 0.02 15.4 4.3 2.4 1 1 1 2 2 2 2 Apg6 coiled-coil region Noelin-1 PF12308.8 CEH13400.1 - 0.22 11.5 3.8 4.7 7.3 0.7 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein FAM76 PF16046.5 CEH13400.1 - 0.23 10.8 3.4 0.32 10.3 3.4 1.2 1 0 0 1 1 1 0 FAM76 protein Fez1 PF06818.15 CEH13400.1 - 3.4 8.1 10.8 2.4 8.6 8.9 1.6 1 1 1 2 2 2 0 Fez1 MutS_V PF00488.21 CEH13402.1 - 8e-63 211.9 0.0 1.4e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CEH13402.1 - 5.8e-35 121.3 5.0 1.6e-34 119.8 5.0 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CEH13402.1 - 5.8e-18 65.2 0.0 1.3e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CEH13402.1 - 5.3e-09 36.5 0.0 2e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 CEH13402.1 - 0.0055 16.3 0.1 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CEH13402.1 - 0.085 13.3 0.1 0.99 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Smr PF01713.21 CEH13403.1 - 1.2e-09 38.4 0.7 4.8e-09 36.5 0.1 2.4 2 0 0 2 2 2 1 Smr domain CUE PF02845.16 CEH13403.1 - 1.7e-06 27.6 0.0 9.1e-06 25.3 0.0 2.2 3 0 0 3 3 3 1 CUE domain DUF1771 PF08590.10 CEH13403.1 - 2.6e-06 27.7 4.8 2.6e-06 27.7 4.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) UBA PF00627.31 CEH13403.1 - 0.005 16.7 1.8 0.025 14.5 0.4 2.9 3 0 0 3 3 3 1 UBA/TS-N domain GvpL_GvpF PF06386.11 CEH13403.1 - 0.0088 16.0 1.0 0.025 14.5 1.0 1.7 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF DUF1400 PF07176.11 CEH13403.1 - 0.28 11.5 4.7 6.2 7.1 0.1 3.1 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) COQ7 PF03232.13 CEH13404.1 - 2.1e-66 222.9 0.1 2.7e-66 222.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 CEH13404.1 - 0.00088 19.7 0.0 0.0015 18.9 0.0 1.5 2 0 0 2 2 2 1 Rubrerythrin Ferritin PF00210.24 CEH13404.1 - 0.002 18.1 0.0 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 Ferritin-like domain MgtE_N PF03448.17 CEH13404.1 - 0.017 15.7 0.3 0.06 13.9 0.0 1.9 2 0 0 2 2 2 0 MgtE intracellular N domain FliG_N PF14842.6 CEH13404.1 - 0.1 13.2 0.1 0.84 10.2 0.0 2.3 2 0 0 2 2 2 0 FliG N-terminal domain Polysacc_deac_1 PF01522.21 CEH13406.1 - 9.6e-21 74.0 0.0 1.8e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Asparaginase PF00710.20 CEH13407.1 - 6.1e-54 182.5 0.0 4.7e-53 179.6 0.0 2.2 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CEH13407.1 - 5.8e-15 55.5 0.0 1.9e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 CEH13407.1 - 2.2e-08 34.6 0.1 9.3e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEH13407.1 - 5.4e-07 30.0 0.4 1.8e-06 28.4 0.4 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CEH13407.1 - 7.9e-06 26.1 2.3 0.025 15.0 0.3 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CEH13407.1 - 5.2e-05 23.5 2.1 0.012 15.9 0.2 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEH13407.1 - 6.2e-05 23.1 0.3 0.075 13.6 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat APC1_C PF18122.1 CEH13407.1 - 0.03 14.3 0.2 0.086 12.8 0.2 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain adh_short PF00106.25 CEH13408.1 - 2.2e-06 27.3 0.0 0.029 13.8 0.0 2.5 1 1 1 2 2 2 2 short chain dehydrogenase FA_hydroxylase PF04116.13 CEH13409.1 - 4e-23 82.2 21.2 8.7e-23 81.1 21.2 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily ESSS PF10183.9 CEH13410.1 - 3.2e-07 30.5 0.0 3.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TPR_19 PF14559.6 CEH13412.1 - 5.1e-11 42.9 13.4 2e-05 25.0 0.4 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEH13412.1 - 2.6e-08 33.5 2.8 0.95 9.8 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEH13412.1 - 2.4e-06 27.7 32.9 0.0029 17.9 0.5 8.9 10 1 1 11 11 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEH13412.1 - 6.3e-06 25.8 1.8 0.0031 17.2 0.1 4.6 5 0 0 5 5 5 1 TPR repeat TPR_2 PF07719.17 CEH13412.1 - 7.3e-06 25.7 31.1 1.2 9.5 0.0 10.9 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEH13412.1 - 8e-06 25.5 8.0 12 5.9 0.0 9.6 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEH13412.1 - 3.1e-05 24.4 36.5 0.00029 21.4 0.1 11.8 12 1 1 13 13 12 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEH13412.1 - 7.5e-05 22.8 0.5 0.19 12.2 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEH13412.1 - 9.4e-05 22.8 7.8 25 5.8 0.1 7.9 7 0 0 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH13412.1 - 0.00039 20.6 5.2 0.013 15.7 0.4 4.8 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Complex1_LYR PF05347.15 CEH13412.1 - 0.0011 19.0 0.2 0.008 16.2 0.0 2.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) TPR_20 PF14561.6 CEH13412.1 - 0.0024 18.1 2.2 0.058 13.7 0.1 4.3 4 1 1 5 5 3 1 Tetratricopeptide repeat Na_Ca_ex_C PF16494.5 CEH13412.1 - 0.0041 17.6 0.0 0.021 15.3 0.0 2.2 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain TPR_16 PF13432.6 CEH13412.1 - 0.014 16.1 0.1 0.014 16.1 0.1 8.4 10 1 1 11 11 9 0 Tetratricopeptide repeat SidC_N PF18219.1 CEH13412.1 - 0.088 11.8 0.0 0.39 9.6 0.0 1.8 1 1 1 2 2 2 0 SidC N-terminal domain Complex1_LYR_2 PF13233.6 CEH13412.1 - 0.18 12.6 3.1 0.37 11.6 0.1 3.3 3 0 0 3 3 2 0 Complex1_LYR-like TPR_4 PF07721.14 CEH13412.1 - 0.7 10.7 13.0 3 8.7 0.0 6.7 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEH13412.1 - 1.4 9.1 11.2 22 5.4 0.1 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEH13412.1 - 1.8 8.5 20.1 1.5 8.8 0.2 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Alanine_zipper PF11839.8 CEH13412.1 - 2.1 8.8 10.4 9.3 6.7 10.4 2.2 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein RCC1 PF00415.18 CEH13413.1 - 3.1e-53 178.2 17.4 2.4e-10 40.9 0.1 8.7 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEH13413.1 - 3.7e-31 106.3 26.6 4.5e-08 32.7 0.7 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat DHquinase_II PF01220.19 CEH13414.1 - 2.1e-58 195.9 0.1 2.4e-58 195.7 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Peripla_BP_1 PF00532.21 CEH13414.1 - 0.018 14.5 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family PCNA_N PF00705.18 CEH13414.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain GTF2I PF02946.14 CEH13414.1 - 0.23 11.6 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 GTF2I-like repeat MCM PF00493.23 CEH13415.1 - 1.9e-45 154.7 0.1 5.5e-25 87.8 0.0 2.3 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 CEH13415.1 - 1.3e-29 102.6 0.0 2.2e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEH13415.1 - 1.4e-18 67.1 0.8 3.2e-18 65.9 0.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CEH13415.1 - 3.3e-13 50.1 0.0 6.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase_C PF13335.6 CEH13415.1 - 0.049 14.3 0.6 0.2 12.3 0.6 2.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal DUF4449 PF14613.6 CEH13416.1 - 1.5e-08 34.9 0.7 1.5e-08 34.9 0.7 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) Neugrin PF06413.11 CEH13416.1 - 4.6e-07 30.1 1.3 4.6e-07 30.1 1.3 4.2 4 2 1 5 5 5 1 Neugrin RsfS PF02410.15 CEH13416.1 - 4.8e-07 30.1 0.2 5.3e-06 26.8 0.0 2.8 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation MRP-L20 PF12824.7 CEH13416.1 - 0.00021 21.5 3.6 0.00021 21.5 3.6 3.6 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.12 CEH13416.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 HTH domain FAD_binding_3 PF01494.19 CEH13417.1 - 2.4e-19 69.8 2.8 1.2e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 CEH13417.1 - 2.9e-06 26.6 0.0 4.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CEH13417.1 - 8.4e-05 21.9 3.2 0.0012 18.1 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEH13417.1 - 8.7e-05 22.7 3.3 0.0002 21.5 2.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CEH13417.1 - 0.00089 18.2 3.6 0.57 9.0 0.9 3.2 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.24 CEH13417.1 - 0.0016 18.1 1.2 0.016 14.8 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CEH13417.1 - 0.0045 16.3 0.2 0.0092 15.2 0.2 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 CEH13417.1 - 0.0089 15.2 0.1 0.016 14.3 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 CEH13417.1 - 0.016 14.9 0.3 0.031 13.9 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 CEH13417.1 - 0.019 15.5 6.0 0.072 13.7 0.7 3.4 5 0 0 5 5 4 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 CEH13417.1 - 0.03 13.4 0.0 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase FAD_oxidored PF12831.7 CEH13417.1 - 0.082 12.2 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CEH13417.1 - 0.25 10.0 2.2 0.23 10.1 0.9 1.5 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 CEH13417.1 - 0.29 10.4 2.4 1.2 8.3 0.3 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase PXA PF02194.15 CEH13418.1 - 9.5e-28 97.4 2.6 9.5e-28 97.4 2.6 2.0 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.12 CEH13418.1 - 4.1e-07 30.6 0.0 1.5e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Sorting nexin C terminal adh_short PF00106.25 CEH13419.1 - 3.3e-34 118.1 0.5 5.9e-27 94.4 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEH13419.1 - 1.6e-18 67.1 0.0 1.3e-16 60.8 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH13419.1 - 8.2e-05 22.6 0.3 0.42 10.5 0.0 2.4 1 1 0 2 2 2 2 KR domain Sld5 PF05916.11 CEH13420.1 - 0.00019 21.8 0.9 0.00045 20.6 0.9 1.7 1 1 0 1 1 1 1 GINS complex protein Proteasome PF00227.26 CEH13421.1 - 5.3e-45 153.3 4.5 1.3e-42 145.5 0.3 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 CEH13421.1 - 7.3e-15 54.3 0.4 1.3e-14 53.5 0.4 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ATP-synt_Eps PF04627.13 CEH13422.1 - 8e-18 64.2 0.7 1e-17 63.8 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain MotY_N PF18393.1 CEH13422.1 - 0.031 14.4 0.2 0.038 14.1 0.2 1.1 1 0 0 1 1 1 0 MotY N-terminal domain Ribosomal_L23 PF00276.20 CEH13423.1 - 0.00036 20.8 0.0 0.00084 19.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 RdRP_4 PF02123.16 CEH13423.1 - 0.055 12.3 1.5 0.088 11.7 1.5 1.2 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase Fmp27_WPPW PF10359.9 CEH13423.1 - 0.52 9.1 7.0 0.85 8.4 7.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF572 PF04502.13 CEH13424.1 - 6.1e-56 190.4 12.8 6.1e-56 190.4 12.8 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF572) DUF866 PF05907.13 CEH13424.1 - 0.076 12.9 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) HypA PF01155.19 CEH13424.1 - 0.15 12.0 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 CEH13424.1 - 0.24 11.8 1.9 0.71 10.3 1.9 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-ACC PF17848.1 CEH13424.1 - 1.1 9.4 4.3 25 5.1 0.5 2.8 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DUF1451 PF07295.11 CEH13424.1 - 5.8 7.0 6.9 1.4 9.0 1.6 2.5 2 1 1 3 3 3 0 Zinc-ribbon containing domain CDC45 PF02724.14 CEH13425.1 - 5.6e-34 117.5 0.0 6.4e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein CDC45 PF02724.14 CEH13426.1 - 1.2e-80 271.7 0.5 1.5e-80 271.3 0.5 1.2 1 0 0 1 1 1 1 CDC45-like protein MiaE_2 PF13794.6 CEH13426.1 - 0.18 11.5 1.7 10 5.7 0.1 2.7 2 1 1 3 3 3 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like eIF-1a PF01176.19 CEH13427.1 - 1.5e-21 75.9 0.0 2.1e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RRM_1 PF00076.22 CEH13428.1 - 4.7e-07 29.5 0.0 9.3e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_22 PF03901.17 CEH13432.1 - 8.5e-65 219.6 16.6 1.2e-63 215.8 16.6 2.2 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family SQS_PSY PF00494.19 CEH13433.1 - 2.2e-36 125.7 0.0 3e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase TctB PF07331.11 CEH13433.1 - 0.054 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family ADH_zinc_N_2 PF13602.6 CEH13434.1 - 1.1e-17 65.3 0.0 3e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CEH13434.1 - 4.3e-09 36.4 0.0 1.2e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH13434.1 - 0.00036 20.4 0.0 0.00088 19.1 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CEH13434.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Eno-Rase_NADH_b PF12242.8 CEH13434.1 - 0.11 12.2 0.2 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UAA PF08449.11 CEH13435.1 - 6.8e-07 28.8 15.6 1.2e-05 24.7 15.6 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 CEH13435.1 - 0.00036 20.7 4.6 0.00036 20.7 4.6 2.9 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 CEH13435.1 - 0.0087 15.4 13.7 0.04 13.3 0.7 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family HS1_rep PF02218.15 CEH13435.1 - 0.058 13.7 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Repeat in HS1/Cortactin PHO4 PF01384.20 CEH13435.1 - 0.27 10.2 13.9 0.13 11.3 3.8 2.5 1 1 1 2 2 2 0 Phosphate transporter family MTHFR PF02219.17 CEH13437.1 - 7.7e-108 360.1 0.0 1.1e-107 359.7 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TFIIB PF00382.19 CEH13438.1 - 1e-29 102.4 0.1 1.2e-17 63.7 0.0 3.3 2 1 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CEH13438.1 - 2.7e-22 79.0 2.2 2.7e-22 79.0 2.2 4.1 3 2 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CEH13438.1 - 4.4e-05 22.9 1.3 9.6e-05 21.8 1.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding GPS2_interact PF15784.5 CEH13438.1 - 0.059 13.8 0.2 0.059 13.8 0.2 2.4 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain OrfB_Zn_ribbon PF07282.11 CEH13438.1 - 0.062 13.2 1.0 0.15 12.0 1.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2318 PF10080.9 CEH13438.1 - 0.082 13.0 0.4 0.15 12.2 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zinc-ribbons_6 PF07191.12 CEH13438.1 - 0.2 11.6 0.4 0.36 10.8 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbons Ribosomal_S27e PF01667.17 CEH13438.1 - 0.31 10.8 1.0 0.55 10.0 1.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 Rep_fac-A_C PF08646.10 CEH13439.1 - 4.1e-55 185.6 4.3 2.9e-54 182.8 1.8 2.2 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CEH13439.1 - 1.3e-31 108.3 0.0 5.7e-31 106.3 0.0 2.0 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 CEH13439.1 - 1.4e-10 41.0 0.3 5.1e-09 36.0 0.1 3.0 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 CEH13439.1 - 1.7e-06 28.2 1.3 6.1e-05 23.3 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF223 Rep-A_N PF04057.12 CEH13439.1 - 9.2e-06 25.6 0.2 1.8e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF4539 PF15072.6 CEH13439.1 - 0.062 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) IBR PF01485.21 CEH13439.1 - 0.084 13.1 1.4 0.18 12.0 1.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Drc1-Sld2 PF11719.8 CEH13440.1 - 5.9e-09 36.0 1.6 5.9e-09 36.0 1.6 2.6 1 1 1 2 2 2 1 DNA replication and checkpoint protein Sigma70_r3 PF04539.16 CEH13440.1 - 0.022 14.9 0.1 0.22 11.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-70 region 3 RRP36 PF06102.12 CEH13442.1 - 1.3e-36 126.1 18.4 1.3e-36 126.1 18.4 3.7 3 2 0 3 3 3 1 rRNA biogenesis protein RRP36 Urb2 PF10441.9 CEH13443.1 - 2.4e-36 125.6 0.8 2.4e-36 125.6 0.8 5.5 4 1 1 5 5 5 2 Urb2/Npa2 family Pkinase PF00069.25 CEH13444.1 - 2.9e-65 220.3 0.0 3.4e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH13444.1 - 4.1e-32 111.5 0.0 5.2e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH13444.1 - 3.9e-05 23.1 0.0 6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEH13444.1 - 0.00029 19.9 0.1 0.0026 16.8 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEH13444.1 - 0.0024 17.8 0.0 0.0038 17.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CEH13444.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 CEH13444.1 - 0.22 10.8 0.2 0.6 9.4 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 CEH13446.1 - 2.3e-34 118.9 10.9 2.3e-34 118.9 10.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Aminotran_4 PF01063.19 CEH13446.1 - 3.7e-14 53.1 0.0 6.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV Sugar_tr PF00083.24 CEH13446.1 - 3.3e-10 39.4 0.4 3.3e-10 39.4 0.4 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CEH13446.1 - 0.0093 14.4 0.4 0.019 13.4 0.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SelB-wing_2 PF09106.11 CEH13446.1 - 0.036 14.3 0.6 0.21 11.8 0.2 2.4 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DUF1295 PF06966.12 CEH13446.1 - 0.036 13.6 0.2 0.074 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) PKcGMP_CC PF16808.5 CEH13446.1 - 0.13 12.2 0.8 0.26 11.2 0.8 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MFS_4 PF06779.14 CEH13446.1 - 0.13 11.5 9.3 0.012 14.9 2.1 2.2 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 CEH13446.1 - 0.5 9.2 4.5 0.53 9.1 0.1 2.5 2 1 0 2 2 2 0 MFS_1 like family FAD_binding_1 PF00667.20 CEH13447.1 - 3.7e-24 85.5 0.0 5.1e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CEH13447.1 - 1.6e-11 44.8 0.0 4.2e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Fib_alpha PF08702.10 CEH13450.1 - 0.022 15.0 2.0 0.03 14.5 2.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 CEH13450.1 - 0.038 14.5 3.3 0.053 14.0 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Dynactin_p22 PF07426.11 CEH13450.1 - 0.16 11.8 3.4 0.21 11.4 3.4 1.1 1 0 0 1 1 1 0 Dynactin subunit p22 PKcGMP_CC PF16808.5 CEH13450.1 - 0.62 10.0 5.1 2.5 8.0 0.2 2.7 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SET PF00856.28 CEH13451.1 - 0.0031 17.9 0.5 0.071 13.5 0.0 2.3 1 1 0 2 2 2 1 SET domain SYS1 PF09801.9 CEH13452.1 - 3.4e-13 50.0 2.7 1e-09 38.7 2.3 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DUF4229 PF14012.6 CEH13452.1 - 2.6 8.2 8.0 18 5.5 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Cullin PF00888.22 CEH13453.1 - 0.075 11.6 0.0 0.58 8.7 0.0 2.0 2 0 0 2 2 2 0 Cullin family DUF1771 PF08590.10 CEH13454.1 - 1.7e-10 41.1 3.9 1.7e-10 41.1 3.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 CEH13454.1 - 0.00041 20.7 0.2 0.0011 19.2 0.2 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH_3 PF15663.5 CEH13454.1 - 0.047 13.9 5.3 0.38 11.0 5.3 2.1 1 1 1 2 2 2 0 Zinc-finger containing family CUE PF02845.16 CEH13454.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 CUE domain HBS1_N PF08938.10 CEH13454.1 - 0.16 12.3 0.3 0.34 11.2 0.0 1.6 2 0 0 2 2 2 0 HBS1 N-terminus zf-CCCH PF00642.24 CEH13454.1 - 0.17 11.9 5.6 2 8.4 0.3 2.4 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CEH13454.1 - 0.52 10.9 6.6 3.2 8.4 1.0 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEH13454.1 - 0.93 10.2 4.4 3.5 8.4 0.2 2.3 1 1 1 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 CEH13454.1 - 2.4 8.4 6.5 8 6.7 0.6 2.8 2 1 0 2 2 2 0 Zinc finger domain Asp PF00026.23 CEH13456.1 - 4.6e-42 144.6 0.9 5.4e-42 144.3 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEH13456.1 - 0.0083 16.4 1.1 0.5 10.6 0.3 2.5 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal SRF-TF PF00319.18 CEH13457.1 - 1.1e-22 79.2 0.0 1.8e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Hydantoinase_A PF01968.18 CEH13458.1 - 6.3e-89 298.1 0.0 1.6e-88 296.8 0.0 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CEH13458.1 - 8.6e-61 204.7 1.0 4.3e-60 202.5 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Prenyltrans PF00432.21 CEH13459.1 - 7.6e-31 105.5 2.0 1.2e-09 37.7 0.2 3.5 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat Nbl1_Borealin_N PF10444.9 CEH13460.1 - 0.056 13.1 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Ribosomal_L12_N PF16320.5 CEH13461.1 - 1.4e-09 37.5 17.2 10 5.9 0.0 9.2 9 0 0 9 9 9 2 Ribosomal protein L7/L12 dimerisation domain HTH_1 PF00126.27 CEH13461.1 - 5.2e-06 26.3 0.0 15 5.6 0.0 5.4 4 3 2 6 6 6 2 Bacterial regulatory helix-turn-helix protein, lysR family CheC PF04509.12 CEH13461.1 - 7.5e-05 22.5 6.4 17 5.4 0.0 6.2 8 0 0 8 8 8 0 CheC-like family sCache_2 PF17200.4 CEH13461.1 - 8.3e-05 22.5 0.0 21 4.9 0.0 4.0 2 1 2 4 4 4 0 Single Cache domain 2 IF3_N PF05198.16 CEH13461.1 - 0.00021 21.5 1.1 0.059 13.6 0.1 3.0 2 1 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain CitT PF12431.8 CEH13461.1 - 0.0018 18.6 1.2 57 4.2 0.0 4.3 4 0 0 4 4 4 0 Transcriptional regulator LPD14 PF18827.1 CEH13461.1 - 0.002 18.4 0.5 17 5.6 0.0 3.8 1 1 2 4 4 4 0 Large polyvalent protein-associated domain 14 VWA_2 PF13519.6 CEH13461.1 - 0.098 13.3 4.6 27 5.5 0.0 4.7 1 1 4 5 5 5 0 von Willebrand factor type A domain DUF3913 PF13052.6 CEH13461.1 - 0.17 12.2 1.5 70 3.8 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3913) tRNA_synt_1c_R1 PF04558.15 CEH13461.1 - 0.22 11.5 1.3 1.3 9.0 0.1 2.5 1 1 2 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 FCD PF07729.12 CEH13461.1 - 0.79 10.2 3.5 16 5.9 0.0 3.6 4 0 0 4 4 4 0 FCD domain ABC2_membrane PF01061.24 CEH13462.1 - 2.7e-56 190.3 48.5 1e-30 106.7 15.2 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CEH13462.1 - 1.3e-36 126.2 0.2 8.4e-17 62.0 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 CEH13462.1 - 1.1e-29 102.2 6.9 4.1e-24 84.3 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CEH13462.1 - 2.3e-13 50.5 0.0 5.2e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CEH13462.1 - 1.4e-08 35.3 0.8 4.1e-05 24.0 0.4 3.0 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CEH13462.1 - 1.8e-06 27.9 0.5 1.5e-05 25.0 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_21 PF13304.6 CEH13462.1 - 5.6e-05 23.1 0.2 0.05 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CEH13462.1 - 0.0004 20.0 0.1 0.0056 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CEH13462.1 - 0.0016 18.3 0.2 0.15 12.0 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 CEH13462.1 - 0.0051 17.1 3.7 0.11 12.8 0.3 3.5 3 1 0 3 3 3 1 AAA domain SMC_N PF02463.19 CEH13462.1 - 0.0052 16.2 0.0 0.41 10.0 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEH13462.1 - 0.0094 15.7 0.8 0.23 11.2 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 CEH13462.1 - 0.02 15.1 0.1 0.26 11.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CEH13462.1 - 0.024 15.2 0.0 1.8 9.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 CEH13462.1 - 0.028 14.9 0.3 3.7 8.0 0.2 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 CEH13462.1 - 0.065 13.3 0.7 0.74 9.9 0.2 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase dNK PF01712.19 CEH13462.1 - 0.093 12.6 0.1 0.85 9.4 0.0 2.4 3 0 0 3 3 2 0 Deoxynucleoside kinase DnaB_C PF03796.15 CEH13462.1 - 0.12 11.7 0.1 0.91 8.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain TsaE PF02367.17 CEH13462.1 - 0.14 12.2 1.2 0.3 11.1 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 CEH13462.1 - 0.14 11.8 2.2 1.6 8.3 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 CEH13462.1 - 0.23 11.7 3.7 0.76 10.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 CEH13462.1 - 0.37 11.3 2.5 0.3 11.5 0.1 2.0 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 CEH13462.1 - 3.6 7.2 6.3 1.5 8.5 0.4 2.8 3 0 0 3 3 2 0 AAA domain Thioredoxin PF00085.20 CEH13463.1 - 4.8e-41 138.9 0.0 2e-20 72.7 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CEH13463.1 - 3.2e-09 37.0 0.0 0.033 14.1 0.0 4.2 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CEH13463.1 - 7.8e-06 26.3 0.0 0.048 14.1 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEH13463.1 - 0.00038 20.7 0.5 0.031 14.6 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 CEH13463.1 - 0.011 15.8 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain DSBA PF01323.20 CEH13463.1 - 0.013 15.3 0.6 4.3 7.1 0.2 2.3 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_7 PF13899.6 CEH13463.1 - 0.025 14.8 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 CEH13463.1 - 0.051 13.5 0.2 0.9 9.5 0.0 2.6 3 0 0 3 3 3 0 AhpC/TSA family zf-U1 PF06220.12 CEH13463.1 - 0.13 12.0 0.2 0.31 10.9 0.2 1.5 1 0 0 1 1 1 0 U1 zinc finger OST3_OST6 PF04756.13 CEH13463.1 - 0.18 11.1 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 CEH13463.1 - 0.2 11.8 1.2 17 5.5 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin TraF PF13728.6 CEH13463.1 - 1.4 8.7 0.0 1.4 8.7 0.0 3.8 3 1 0 3 3 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 CEH13463.1 - 4.9 7.4 6.4 1.8 8.8 0.4 2.5 2 0 0 2 2 2 0 Glutaredoxin Amino_oxidase PF01593.24 CEH13464.1 - 3e-23 82.8 0.0 4e-20 72.5 0.0 2.3 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEH13464.1 - 2.7e-12 46.7 0.4 8.6e-12 45.1 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEH13464.1 - 1.9e-10 40.5 0.5 4.1e-06 26.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEH13464.1 - 2e-10 40.8 2.3 2.3e-09 37.3 2.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEH13464.1 - 3.9e-07 29.5 1.5 6.6e-05 22.2 1.6 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 CEH13464.1 - 3.8e-05 24.2 3.5 0.004 17.7 1.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEH13464.1 - 4.9e-05 22.2 0.5 0.0021 16.9 0.9 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CEH13464.1 - 5.4e-05 22.7 0.2 0.0017 17.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CEH13464.1 - 9e-05 21.9 1.5 0.001 18.4 1.7 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CEH13464.1 - 0.0017 17.6 0.2 0.0035 16.6 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 CEH13464.1 - 0.002 17.3 3.2 0.023 13.7 0.4 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein ApbA PF02558.16 CEH13464.1 - 0.0024 17.5 2.3 0.0047 16.6 2.3 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 CEH13464.1 - 0.0094 16.0 1.0 0.066 13.2 0.2 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 CEH13464.1 - 0.0095 16.0 0.2 0.016 15.2 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.19 CEH13464.1 - 0.044 13.1 0.1 5.7 6.2 0.0 2.4 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 CEH13464.1 - 0.077 12.2 0.8 0.14 11.4 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CEH13464.1 - 0.08 12.8 1.2 0.14 12.0 1.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 CEH13464.1 - 0.17 11.8 0.5 0.36 10.8 0.5 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.14 CEH13464.1 - 0.27 10.0 5.4 4.1 6.2 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.25 CEH13464.1 - 0.32 10.4 1.7 0.55 9.7 1.7 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GIDA PF01134.22 CEH13464.1 - 2.8 6.9 5.4 1.1 8.2 2.6 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Bac_rhodopsin PF01036.18 CEH13465.1 - 3.6e-49 167.4 15.0 4.3e-49 167.1 15.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Gaa1 PF04114.14 CEH13465.1 - 0.019 14.0 3.2 0.027 13.5 3.2 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component RPE65 PF03055.15 CEH13466.1 - 1.8e-108 363.7 0.0 2.1e-108 363.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CTD_bind PF04818.13 CEH13467.1 - 9e-05 23.2 0.1 0.0004 21.1 0.1 2.1 1 1 0 1 1 1 1 RNA polymerase II-binding domain. FadR_C PF07840.12 CEH13467.1 - 0.35 10.8 1.1 0.58 10.0 1.1 1.6 1 1 0 1 1 1 0 FadR C-terminal domain HD PF01966.22 CEH13470.1 - 4.3e-05 23.7 0.8 8.5e-05 22.8 0.8 1.5 1 0 0 1 1 1 1 HD domain RCC1_2 PF13540.6 CEH13474.1 - 8.2e-09 35.0 10.0 2.5e-05 23.9 0.1 4.8 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CEH13474.1 - 3.5e-07 30.7 6.5 0.27 11.9 0.1 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 CEH13474.1 - 6.9e-05 22.7 1.5 7.3e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 F-box-like Hira PF07569.11 CEH13474.1 - 0.045 13.5 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 TUP1-like enhancer of split F-box PF00646.33 CEH13474.1 - 0.15 12.0 0.1 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 F-box domain Ala_racemase_N PF01168.20 CEH13475.1 - 1.7e-14 54.0 0.0 6.5e-11 42.3 0.0 2.3 1 1 1 2 2 2 2 Alanine racemase, N-terminal domain Glyoxalase PF00903.25 CEH13476.1 - 9.9e-19 67.8 0.1 1.3e-18 67.4 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 CEH13476.1 - 0.091 12.8 0.1 0.15 12.1 0.1 1.7 1 1 0 1 1 1 0 CppA N-terminal Glyoxalase_4 PF13669.6 CEH13476.1 - 0.097 12.9 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.25 CEH13477.1 - 3.6e-27 95.1 0.0 5.5e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH13477.1 - 2.5e-11 43.6 0.0 3.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH13477.1 - 2.8e-05 24.1 0.0 6.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Telomere_reg-2 PF10193.9 CEH13478.1 - 2.3e-30 105.2 0.0 6.9e-30 103.7 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein Ribosomal_L34 PF00468.17 CEH13478.1 - 0.083 12.9 0.5 0.18 11.8 0.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L34 SRP14 PF02290.15 CEH13479.1 - 5.3e-18 65.2 0.6 1e-17 64.2 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle 14kD protein GlcNAc PF11397.8 CEH13479.1 - 0.082 12.3 0.5 0.12 11.8 0.5 1.1 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) CPSase_L_D2 PF02786.17 CEH13480.1 - 2.2e-111 370.4 0.0 1.1e-81 273.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CEH13480.1 - 5.1e-48 162.1 0.0 1e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CEH13480.1 - 9.7e-45 152.7 0.0 8.5e-44 149.6 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 CEH13480.1 - 1.1e-43 148.8 0.0 2.1e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 CEH13480.1 - 1.3e-38 132.1 0.0 2.8e-38 131.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CEH13480.1 - 6.7e-31 107.5 0.0 1.2e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 CEH13480.1 - 1.6e-16 60.4 0.1 4.7e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CEH13480.1 - 9.7e-16 57.8 0.0 1.8e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CEH13480.1 - 4.4e-11 42.6 0.1 2.5e-05 24.1 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 CEH13480.1 - 4.9e-10 39.5 0.0 2.3e-09 37.3 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain Peptidase_C26 PF07722.13 CEH13480.1 - 1.6e-05 24.8 0.4 0.0016 18.3 0.1 2.7 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 CEH13480.1 - 6.6e-05 23.0 0.0 0.22 11.6 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 CEH13480.1 - 0.00023 21.0 0.0 0.18 11.6 0.0 3.6 3 0 0 3 3 3 1 DJ-1/PfpI family TrkA_N PF02254.18 CEH13480.1 - 0.011 15.9 0.0 0.51 10.6 0.0 3.3 3 0 0 3 3 3 0 TrkA-N domain GARS_A PF01071.19 CEH13480.1 - 0.028 14.2 0.0 0.3 10.8 0.0 2.7 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain UPF0172 PF03665.13 CEH13481.1 - 3.9e-32 111.9 0.0 4.6e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) WES_acyltransf PF03007.16 CEH13482.1 - 9.8e-09 35.3 0.0 9.8e-09 35.3 0.0 2.1 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 CEH13482.1 - 2.7e-07 30.7 0.0 6.2e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1298) Pex14_N PF04695.13 CEH13482.1 - 0.35 11.5 15.3 0.26 11.9 11.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cyt-b5 PF00173.28 CEH13483.1 - 1.7e-22 79.3 0.0 1.9e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CHORD PF04968.12 CEH13484.1 - 5e-23 81.6 5.1 5e-23 81.6 5.1 1.7 2 0 0 2 2 2 1 CHORD CS PF04969.16 CEH13484.1 - 1.1e-06 29.6 0.1 1.7e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 CS domain Mito_carr PF00153.27 CEH13485.1 - 1.4e-13 50.5 0.1 1.8e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.27 CEH13486.1 - 8.9e-17 60.8 0.0 1.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein RraA-like PF03737.15 CEH13487.1 - 5.4e-36 124.0 0.0 6.7e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA HECT PF00632.25 CEH13488.1 - 1.1e-71 241.8 0.0 1.5e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RIX1 PF08167.12 CEH13488.1 - 0.012 15.4 0.0 0.062 13.0 0.0 2.2 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis LtrA PF06772.11 CEH13489.1 - 1.5e-33 116.5 19.2 2.1e-33 116.0 19.2 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) zf-C2H2 PF00096.26 CEH13492.1 - 1.2e-07 31.8 7.6 0.0026 18.1 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEH13492.1 - 2.4e-05 24.8 7.0 0.028 15.2 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEH13492.1 - 0.59 10.7 3.0 0.63 10.6 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Q_salvage PF10343.9 CEH13493.1 - 1.1e-05 25.2 0.0 0.00028 20.5 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family Glycos_transf_2 PF00535.26 CEH13494.1 - 3.6e-32 111.5 0.0 4.5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CEH13494.1 - 9.1e-14 51.9 0.0 1.4e-13 51.2 0.0 1.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CEH13494.1 - 4.6e-06 26.3 0.0 6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CEH13494.1 - 0.00066 19.2 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Ank_4 PF13637.6 CEH13495.1 - 2.7e-15 56.5 0.4 2.6e-09 37.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEH13495.1 - 4.5e-13 49.1 0.9 1.1e-06 28.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEH13495.1 - 8.4e-11 41.1 0.1 8.2e-05 22.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CEH13495.1 - 1.9e-08 34.8 0.0 3.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CEH13495.1 - 3.5e-05 24.1 0.1 0.0016 18.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Methyltransf_25 PF13649.6 CEH13495.1 - 0.0054 17.4 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CEH13495.1 - 0.057 14.5 0.0 0.24 12.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Acetyltransf_1 PF00583.25 CEH13497.1 - 7.7e-10 39.0 0.0 1.2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CEH13497.1 - 1.1e-06 28.6 0.0 3.1e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 CEH13497.1 - 1.1e-06 28.5 0.0 3.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEH13497.1 - 5.2e-05 23.6 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CEH13497.1 - 0.0019 18.4 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PfkB PF00294.24 CEH13498.1 - 4.2e-39 134.6 0.0 4.9e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Indigoidine_A PF04227.12 CEH13499.1 - 3.6e-111 371.2 0.7 7.5e-111 370.1 0.7 1.5 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 CEH13499.1 - 3.8e-16 59.3 0.0 7.8e-07 28.7 0.0 2.6 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DAO PF01266.24 CEH13500.1 - 7.1e-23 81.7 0.0 1.3e-21 77.6 0.0 2.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase OPA3 PF07047.12 CEH13502.1 - 2.5e-40 137.1 1.9 4.2e-40 136.4 1.9 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF3782 PF12644.7 CEH13502.1 - 0.0036 17.4 0.2 0.011 15.9 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3782) Peptidase_C48 PF02902.19 CEH13504.1 - 2e-27 96.5 1.3 3.5e-11 43.4 0.1 3.3 2 1 1 3 3 3 3 Ulp1 protease family, C-terminal catalytic domain PG_binding_4 PF12229.8 CEH13504.1 - 0.14 12.4 0.6 0.32 11.3 0.6 1.5 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Alk_phosphatase PF00245.20 CEH13505.1 - 9e-73 245.6 0.0 3.8e-70 236.9 0.0 2.5 1 1 0 1 1 1 1 Alkaline phosphatase CDP-OH_P_transf PF01066.21 CEH13506.1 - 6.4e-13 49.3 1.6 9.7e-13 48.7 0.3 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Thioredoxin_8 PF13905.6 CEH13507.1 - 4.9e-09 36.4 0.0 1.1e-07 32.1 0.0 2.4 3 0 0 3 3 3 1 Thioredoxin-like Forkhead_N PF08430.12 CEH13507.1 - 0.025 15.2 5.6 0.044 14.4 5.6 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region Redoxin PF08534.10 CEH13507.1 - 0.03 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Redoxin Septin PF00735.18 CEH13508.1 - 1.6e-112 375.4 0.2 2.1e-112 375.0 0.2 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CEH13508.1 - 2.6e-09 37.1 0.0 7.1e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEH13508.1 - 1.2e-06 28.5 3.4 2.9e-06 27.3 0.8 2.7 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 CEH13508.1 - 3.2e-06 26.8 2.3 2.7e-05 23.8 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CEH13508.1 - 2.6e-05 24.4 0.2 6.1e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEH13508.1 - 4.1e-05 23.2 0.7 0.00013 21.6 0.5 2.0 2 1 0 2 2 2 1 Ras family AAA_22 PF13401.6 CEH13508.1 - 0.00014 22.1 0.5 0.00052 20.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEH13508.1 - 0.0002 21.8 0.1 0.00061 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 CEH13508.1 - 0.00064 19.1 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 CEH13508.1 - 0.0016 18.9 0.1 0.0049 17.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.9 CEH13508.1 - 0.0042 16.8 0.8 0.16 11.7 0.4 2.6 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 CEH13508.1 - 0.007 16.9 1.1 0.41 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 CEH13508.1 - 0.011 15.5 1.4 2.7 7.7 0.2 2.6 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein FOXP-CC PF16159.5 CEH13508.1 - 0.016 15.8 0.6 0.052 14.2 0.6 1.9 1 0 0 1 1 1 0 FOXP coiled-coil domain AAA_7 PF12775.7 CEH13508.1 - 0.022 14.3 0.1 0.048 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CEH13508.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 CEH13508.1 - 0.024 14.0 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 CEH13508.1 - 0.025 14.3 0.1 0.051 13.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CEH13508.1 - 0.029 13.9 0.2 0.086 12.4 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CEH13508.1 - 0.035 13.4 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CLP1_P PF16575.5 CEH13508.1 - 0.036 13.9 0.1 1.5 8.6 0.0 2.3 1 1 1 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 CEH13508.1 - 0.048 12.9 0.1 0.082 12.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 CEH13508.1 - 0.048 13.4 0.4 0.048 13.4 0.4 2.2 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CEH13508.1 - 0.064 13.0 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.23 CEH13508.1 - 0.065 13.3 5.4 0.49 10.4 0.2 2.7 2 1 1 3 3 3 0 Dynamin family RNA_helicase PF00910.22 CEH13508.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 CEH13508.1 - 0.1 12.6 0.4 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 CEH13508.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_25 PF13481.6 CEH13508.1 - 0.21 11.2 1.3 0.27 10.8 0.1 1.8 2 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 CEH13508.1 - 0.91 9.3 4.8 8.7 6.1 1.0 3.0 2 1 0 2 2 2 0 Bacterial dnaA protein TACC_C PF05010.14 CEH13508.1 - 1.5 8.5 10.4 0.049 13.4 3.5 1.8 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cep57_CLD_2 PF14197.6 CEH13508.1 - 8.4 6.6 9.4 1.6 8.8 3.4 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Casc1_N PF15927.5 CEH13508.1 - 8.9 5.9 13.9 0.06 13.0 5.1 1.8 3 0 0 3 3 1 0 Cancer susceptibility candidate 1 N-terminus zf-CSL PF05207.13 CEH13509.1 - 3.5e-22 77.9 0.6 4.9e-22 77.4 0.6 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 CEH13509.1 - 0.0017 18.4 1.7 0.0027 17.8 1.5 1.5 1 1 0 1 1 1 1 Zinc ribbon domain zf-RING_4 PF14570.6 CEH13509.1 - 0.036 13.9 0.6 0.074 12.9 0.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Terminase_GpA PF05876.12 CEH13509.1 - 0.04 12.5 0.1 0.078 11.5 0.2 1.4 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) zf-RING_7 PF02591.15 CEH13509.1 - 0.041 14.1 0.1 0.093 12.9 0.1 1.5 1 0 0 1 1 1 0 C4-type zinc ribbon domain zinc_ribbon_4 PF13717.6 CEH13509.1 - 0.11 12.5 0.6 0.17 11.9 0.6 1.3 1 0 0 1 1 1 0 zinc-ribbon domain LIP PF03583.14 CEH13511.1 - 9.8e-52 176.0 0.1 1.7e-51 175.3 0.1 1.2 1 0 0 1 1 1 1 Secretory lipase PAS_9 PF13426.7 CEH13511.1 - 1.7e-17 63.6 0.0 4.8e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain RGS PF00615.19 CEH13511.1 - 8.2e-07 29.3 0.3 1.5e-06 28.5 0.3 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_4 PF08448.10 CEH13511.1 - 9.3e-07 29.1 0.0 1.6e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 CEH13511.1 - 4.2e-05 23.5 0.0 0.00019 21.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 CEH13511.1 - 0.00043 20.5 0.0 0.0014 18.9 0.0 1.9 2 0 0 2 2 2 1 PAS fold Prp19 PF08606.11 CEH13511.1 - 0.062 13.3 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 Prp19/Pso4-like 4HBT PF03061.22 CEH13512.1 - 7.5e-11 42.2 0.0 1e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 CEH13512.1 - 0.00058 20.2 0.0 0.00087 19.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily ZZ PF00569.17 CEH13515.1 - 4.8e-08 32.7 28.9 6.8e-07 29.0 0.4 3.6 3 1 0 3 3 3 3 Zinc finger, ZZ type PB1 PF00564.24 CEH13515.1 - 2.6e-06 27.3 0.0 5.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 PB1 domain CAP_N PF01213.19 CEH13515.1 - 2.6 7.4 4.7 0.43 10.0 0.9 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal cobW PF02492.19 CEH13516.1 - 7.1e-32 110.4 0.0 8.8e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CEH13516.1 - 0.00031 19.8 0.1 0.12 11.4 0.0 2.0 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CEH13516.1 - 0.012 16.0 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 CEH13516.1 - 0.032 14.8 0.0 0.052 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CEH13516.1 - 0.056 13.5 0.0 0.35 10.9 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase CbtA PF09490.10 CEH13516.1 - 0.093 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) ABC_tran PF00005.27 CEH13516.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Pox_A32 PF04665.12 CEH13516.1 - 0.26 10.7 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein SelP_N PF04592.14 CEH13516.1 - 0.99 8.8 9.6 1.4 8.3 9.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Anoctamin PF04547.12 CEH13517.1 - 1.8e-95 320.4 1.3 2.3e-95 320.1 1.3 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel UAA PF08449.11 CEH13518.1 - 1.3e-73 247.9 13.7 1.3e-58 198.6 7.2 2.1 2 0 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.15 CEH13518.1 - 0.0042 16.3 1.8 0.0065 15.7 1.8 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF3671 PF12420.8 CEH13518.1 - 0.62 10.2 2.7 0.5 10.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function dsDNA_bind PF01984.20 CEH13519.1 - 2.5e-23 82.5 0.2 3.1e-23 82.2 0.2 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain FMN_dh PF01070.18 CEH13520.1 - 3.9e-119 397.8 0.0 4.7e-119 397.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CEH13520.1 - 2.9e-21 75.4 0.0 7.1e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CEH13520.1 - 0.00068 18.9 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CEH13520.1 - 0.00068 18.7 0.1 0.0014 17.7 0.1 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 CEH13520.1 - 0.015 14.6 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG FAD_binding_4 PF01565.23 CEH13521.1 - 9.5e-22 77.2 1.5 3.1e-21 75.6 1.1 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 CEH13521.1 - 3.9e-11 42.9 0.4 1.2e-10 41.3 0.4 1.8 1 0 0 1 1 1 1 Berberine and berberine like SET PF00856.28 CEH13522.1 - 5.1e-05 23.7 0.0 0.00025 21.5 0.0 1.7 1 1 0 1 1 1 1 SET domain Hexapep PF00132.24 CEH13525.1 - 3.3e-09 36.1 12.5 0.00032 20.3 0.9 4.2 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) DUF3352 PF11832.8 CEH13525.1 - 0.13 10.8 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) WD40 PF00400.32 CEH13526.1 - 5.5e-11 42.8 11.0 0.0028 18.4 0.1 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat AF-4 PF05110.13 CEH13530.1 - 0.25 9.4 4.2 0.37 8.8 4.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LisH PF08513.11 CEH13532.1 - 0.00026 20.8 0.4 0.00044 20.1 0.4 1.4 1 0 0 1 1 1 1 LisH cwf18 PF08315.12 CEH13533.1 - 0.0038 17.9 1.5 0.0065 17.1 1.5 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DUF1713 PF08213.11 CEH13535.1 - 9.4e-10 38.3 23.2 2.6e-09 36.8 23.2 1.8 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pkinase PF00069.25 CEH13536.1 - 3.2e-52 177.5 0.1 4.3e-52 177.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH13536.1 - 3.2e-20 72.5 0.0 5.9e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CEH13536.1 - 0.06 12.3 0.5 0.088 11.8 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Proteasome PF00227.26 CEH13537.1 - 7.9e-60 201.6 0.2 9.7e-60 201.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEH13537.1 - 2.4e-14 52.7 0.2 5.1e-14 51.6 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 CEH13537.1 - 0.05 13.7 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Aminotran_1_2 PF00155.21 CEH13538.1 - 1.9e-83 280.6 0.0 2.2e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF676 PF05057.14 CEH13540.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 CEH13540.1 - 0.0013 19.4 0.1 0.0025 18.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.8 CEH13540.1 - 0.0087 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Lipase_3 PF01764.25 CEH13540.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 CEH13540.1 - 0.043 13.5 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 CEH13540.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 CEH13540.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase MgtE PF01769.16 CEH13541.1 - 1e-36 126.1 23.6 4.1e-20 72.4 6.4 3.7 2 1 1 3 3 3 2 Divalent cation transporter Amidohydro_3 PF07969.11 CEH13542.1 - 3e-16 59.9 0.8 2e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 CEH13542.1 - 3.2e-13 49.7 0.1 8.4e-10 38.5 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family CHCH PF06747.13 CEH13546.1 - 0.00022 21.3 4.6 0.00041 20.4 4.6 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 CEH13546.1 - 0.39 11.2 3.0 0.82 10.1 3.0 1.6 1 0 0 1 1 1 0 GCK domain Na_Ca_ex PF01699.24 CEH13548.1 - 5.9e-38 130.2 25.3 1.8e-19 70.2 9.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3169 PF11368.8 CEH13548.1 - 0.043 13.3 1.1 0.22 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) ATP-synt_8 PF00895.20 CEH13548.1 - 0.78 10.2 3.5 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 DUF4234 PF14018.6 CEH13548.1 - 2.4 8.3 5.0 6 7.1 0.1 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4234) BAR_2 PF10455.9 CEH13549.1 - 6.2e-43 147.0 0.0 1.4e-42 145.9 0.0 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CEH13549.1 - 4.2e-17 62.6 1.7 2.8e-13 50.1 0.7 2.1 2 0 0 2 2 2 2 BAR domain Spectrin PF00435.21 CEH13549.1 - 0.038 14.5 4.8 0.15 12.6 0.1 2.8 2 1 0 2 2 2 0 Spectrin repeat Uds1 PF15456.6 CEH13549.1 - 0.066 13.4 7.1 0.14 12.3 0.0 2.6 2 1 0 2 2 2 0 Up-regulated During Septation MobC PF05713.11 CEH13549.1 - 0.09 13.3 0.1 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) Seryl_tRNA_N PF02403.22 CEH13549.1 - 0.22 11.8 3.7 0.8 10.0 0.0 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 CEH13549.1 - 0.25 10.7 3.3 1.2 8.5 0.0 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Phasin_2 PF09361.10 CEH13549.1 - 0.26 11.6 10.4 0.24 11.7 8.3 2.1 2 0 0 2 2 2 0 Phasin protein ABC_tran_CTD PF16326.5 CEH13549.1 - 1.1 9.6 8.1 2.4 8.5 2.8 2.9 2 2 0 2 2 2 0 ABC transporter C-terminal domain HSCB_C PF07743.13 CEH13549.1 - 5.2 7.6 12.5 0.8 10.2 5.0 3.1 3 2 0 3 3 3 0 HSCB C-terminal oligomerisation domain WGG PF10273.9 CEH13550.1 - 3.2e-18 66.2 0.0 5.1e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Tub_N PF16322.5 CEH13550.1 - 0.039 14.4 1.4 0.06 13.8 1.4 1.3 1 0 0 1 1 1 0 Tubby N-terminal Glyco_transf_17 PF04724.13 CEH13551.1 - 8.8e-125 416.3 0.0 1.1e-124 416.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Phage_holin_2_4 PF16082.5 CEH13551.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like RNase_H PF00075.24 CEH13552.1 - 2.3e-15 57.1 0.0 4.7e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 CEH13552.1 - 0.0017 18.2 0.1 0.0068 16.2 0.1 2.1 2 1 0 2 2 2 1 Reverse transcriptase-like CSRNP_N PF16019.5 CEH13552.1 - 0.14 12.1 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Acetyltransf_7 PF13508.7 CEH13554.1 - 0.00043 20.7 0.0 0.0011 19.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEH13554.1 - 0.0025 17.7 0.0 0.45 10.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEH13554.1 - 0.071 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Phos_pyr_kin PF08543.12 CEH13555.1 - 5.5e-07 29.2 0.0 9.7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CEH13555.1 - 6.3e-05 22.4 0.1 0.00015 21.2 0.0 1.6 2 0 0 2 2 2 1 pfkB family carbohydrate kinase ubiquitin PF00240.23 CEH13556.1 - 3.7e-26 90.7 0.1 4.1e-26 90.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEH13556.1 - 4.8e-14 51.9 0.1 5.3e-14 51.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEH13556.1 - 0.00026 21.4 0.0 0.00068 20.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CEH13556.1 - 0.0013 18.6 0.0 0.0016 18.4 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CEH13556.1 - 0.016 15.6 0.0 0.017 15.5 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain HATPase_c PF02518.26 CEH13556.1 - 0.078 13.5 0.1 0.089 13.3 0.1 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ubiquitin_4 PF18036.1 CEH13556.1 - 0.21 11.7 0.1 13 6.0 0.2 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain GST_C_3 PF14497.6 CEH13558.1 - 9.6e-25 86.7 0.1 6.9e-24 83.9 0.2 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEH13558.1 - 0.0043 17.1 0.0 0.0061 16.5 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEH13558.1 - 0.0094 16.1 0.0 0.021 15.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Gln-synt_N_2 PF16952.5 CEH13559.1 - 0.091 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain Zn_clus PF00172.18 CEH13560.1 - 1.6e-05 24.9 10.4 2.4e-05 24.4 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 CEH13562.1 - 3.6e-14 52.9 3.5 0.0015 19.3 0.0 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH13562.1 - 0.0021 18.3 0.0 59 4.1 0.0 5.0 3 3 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CEH13562.1 - 0.0031 17.2 3.7 0.17 11.5 0.6 3.5 3 1 1 4 4 4 2 PQQ-like domain Nup160 PF11715.8 CEH13562.1 - 0.024 13.3 0.0 0.047 12.3 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CIA30 PF08547.12 CEH13563.1 - 1.1e-18 67.7 0.0 5.1e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) ubiquitin PF00240.23 CEH13565.1 - 4.4e-69 228.2 5.4 7.4e-34 115.3 0.5 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CEH13565.1 - 3.6e-32 110.0 6.4 1.7e-15 56.6 0.6 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEH13565.1 - 7.7e-12 45.5 1.3 0.00027 21.3 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain zf-AN1 PF01428.16 CEH13565.1 - 4.2e-10 39.6 3.6 6.8e-10 38.9 3.6 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger TBK1_ULD PF18396.1 CEH13565.1 - 1.4e-07 31.3 0.3 0.021 14.8 0.1 2.3 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CEH13565.1 - 1.6e-07 31.6 0.4 0.027 14.8 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEH13565.1 - 4.3e-07 30.0 0.3 0.039 14.1 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CEH13565.1 - 4.1e-06 27.3 0.1 0.075 13.6 0.0 2.3 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CEH13565.1 - 0.00014 21.7 0.1 0.5 10.2 0.0 2.3 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 CEH13565.1 - 0.00029 20.8 8.3 10 6.2 0.2 4.2 4 0 0 4 4 4 0 Ubiquitin-like domain DUF3861 PF12977.7 CEH13565.1 - 0.015 15.4 0.2 8.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 CEH13565.1 - 0.019 14.8 0.4 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 ACT domain DUF2870 PF11069.8 CEH13565.1 - 0.027 14.8 0.0 13 6.2 0.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 CEH13565.1 - 0.029 13.7 0.1 0.63 9.3 0.0 2.3 2 0 0 2 2 2 0 RNA methyltransferase Big_7 PF17957.1 CEH13565.1 - 0.049 14.4 0.0 19 6.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig domain TmoB PF06234.12 CEH13565.1 - 0.093 12.8 0.9 20 5.4 0.1 2.7 2 2 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) FlgD_ig PF13860.6 CEH13565.1 - 0.32 10.9 1.3 28 4.6 0.1 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain Tash_PEST PF07708.11 CEH13565.1 - 0.41 10.9 9.6 4.4 7.6 1.5 2.4 2 0 0 2 2 2 0 Tash protein PEST motif Plexin_cytopl PF08337.12 CEH13565.1 - 1.4 7.5 4.3 15 4.1 0.3 2.9 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain F-box-like PF12937.7 CEH13566.1 - 2.7e-06 27.2 0.8 0.0027 17.6 0.3 3.0 2 0 0 2 2 2 2 F-box-like DNA_pol_B_palm PF14792.6 CEH13567.1 - 3.9e-18 65.7 0.0 9.7e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 CEH13567.1 - 1.1e-17 64.0 0.0 2.2e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 CEH13567.1 - 7.2e-10 39.1 0.6 2.2e-09 37.6 0.2 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CEH13567.1 - 9.6e-05 22.1 0.0 0.00028 20.6 0.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.23 CEH13567.1 - 0.0039 17.4 0.0 0.0076 16.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.6 CEH13567.1 - 0.046 14.3 0.0 0.59 10.8 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain AT_hook PF02178.19 CEH13567.1 - 0.13 12.2 5.8 0.6 10.2 5.8 2.3 1 0 0 1 1 1 0 AT hook motif DUF2178 PF09946.9 CEH13568.1 - 0.011 15.9 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Sec2p PF06428.11 CEH13571.1 - 9.8e-06 25.5 5.8 9.8e-06 25.5 5.8 2.6 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p RYDR_ITPR PF01365.21 CEH13571.1 - 0.13 11.6 0.3 0.26 10.7 0.3 1.4 1 0 0 1 1 1 0 RIH domain FA_hydroxylase PF04116.13 CEH13572.1 - 6.2e-20 71.9 6.3 6.2e-20 71.9 6.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1229 PF06797.11 CEH13572.1 - 0.056 13.7 4.8 0.22 11.8 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1229) Ammonium_transp PF00909.21 CEH13574.1 - 1.3e-110 369.9 28.4 1.5e-110 369.7 28.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.25 CEH13575.1 - 3.6e-61 206.8 0.0 3.4e-59 200.4 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH13575.1 - 1.9e-27 96.2 0.1 2.3e-26 92.6 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEH13575.1 - 0.0056 15.7 0.3 0.0082 15.1 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEH13575.1 - 0.0082 16.1 0.4 0.29 11.0 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF809 PF05663.11 CEH13577.1 - 0.78 9.9 3.9 1.3 9.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) G-patch PF01585.23 CEH13577.1 - 3.9 7.4 8.6 1.2 9.1 3.7 2.4 2 0 0 2 2 2 0 G-patch domain Glutaredoxin PF00462.24 CEH13578.1 - 2.7e-21 75.5 0.0 3.4e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CEH13578.1 - 0.00034 20.6 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain GST_N_3 PF13417.6 CEH13578.1 - 0.00063 20.1 0.0 0.0007 20.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 CEH13578.1 - 0.0013 18.6 0.6 0.083 12.7 0.1 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 CEH13578.1 - 0.002 18.6 0.1 0.0051 17.2 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 CEH13578.1 - 0.0026 18.2 0.0 0.0033 17.8 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 CEH13578.1 - 0.019 15.2 0.2 3.2 7.9 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin GST_N_2 PF13409.6 CEH13578.1 - 0.031 14.6 0.0 0.041 14.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain UQ_con PF00179.26 CEH13579.1 - 5e-40 136.4 0.0 6.9e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 CEH13579.1 - 5.2e-16 58.2 0.5 9.3e-16 57.4 0.5 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain FeoA PF04023.14 CEH13579.1 - 0.0025 18.1 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 FeoA domain Prok-E2_B PF14461.6 CEH13579.1 - 0.005 16.5 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_6 PF18039.1 CEH13579.1 - 0.03 14.2 0.1 0.054 13.4 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain UBA PF00627.31 CEH13579.1 - 0.097 12.6 0.1 0.86 9.6 0.0 2.5 3 0 0 3 3 3 0 UBA/TS-N domain Aminotran_1_2 PF00155.21 CEH13580.1 - 4.3e-34 118.3 0.0 5.4e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_31 PF01055.26 CEH13581.1 - 3.6e-107 359.3 2.2 5.5e-107 358.7 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CEH13581.1 - 2.8e-21 75.9 0.1 7e-21 74.6 0.1 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Fungal_trans PF04082.18 CEH13583.1 - 1.6e-21 76.5 0.0 2.7e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH13583.1 - 2.9e-09 36.9 1.9 2.9e-09 36.9 1.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Caleosin PF05042.13 CEH13584.1 - 7.6e-66 221.2 0.0 9.5e-66 220.9 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein CLASP_N PF12348.8 CEH13585.1 - 7.5e-69 231.8 0.0 4.3e-58 196.6 0.0 3.2 2 1 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 CEH13585.1 - 0.0012 19.0 4.7 14 6.2 0.1 6.6 8 0 0 8 8 8 2 HEAT repeat DUF3361 PF11841.8 CEH13585.1 - 0.06 13.3 0.6 2.3 8.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) DUF962 PF06127.11 CEH13586.1 - 1.1e-23 83.1 0.0 1.8e-23 82.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SH3_9 PF14604.6 CEH13588.1 - 4.9e-24 83.9 4.0 2.2e-15 56.2 0.2 2.7 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.20 CEH13588.1 - 2.9e-20 72.3 0.0 5e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 CEH13588.1 - 4.7e-19 67.7 4.6 3.8e-14 52.0 0.2 3.1 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 CEH13588.1 - 1.4e-16 59.9 0.3 7.5e-10 38.3 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain UPF0164 PF03687.13 CEH13588.1 - 0.17 10.6 0.4 0.28 10.0 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) Pkinase_fungal PF17667.1 CEH13590.1 - 1.1e-11 44.1 4.9 1.1e-07 31.0 0.1 3.4 2 2 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 CEH13590.1 - 0.0021 17.1 0.0 0.0042 16.1 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 CEH13590.1 - 0.022 14.2 0.1 0.044 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein kinase domain DUF3318 PF11780.8 CEH13590.1 - 0.15 12.0 0.5 0.52 10.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) ABC2_membrane PF01061.24 CEH13591.1 - 4.8e-74 248.3 64.1 7.6e-40 136.6 29.4 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CEH13591.1 - 4.2e-36 124.5 0.0 2.2e-18 67.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CEH13591.1 - 4.4e-19 68.2 9.0 1.2e-18 66.8 0.2 3.3 3 0 0 3 3 2 1 CDR ABC transporter AAA_21 PF13304.6 CEH13591.1 - 8.1e-06 25.8 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEH13591.1 - 0.00011 21.9 0.9 0.018 14.8 0.1 3.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CEH13591.1 - 0.00018 22.1 0.1 0.0077 16.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 CEH13591.1 - 0.00025 20.3 14.8 0.00025 20.3 14.8 3.3 3 0 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CEH13591.1 - 0.00041 20.3 0.4 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CEH13591.1 - 0.0014 19.0 0.0 0.074 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CEH13591.1 - 0.0015 18.1 0.0 0.0042 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEH13591.1 - 0.0026 17.9 0.0 0.75 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CEH13591.1 - 0.0043 17.0 0.0 0.36 10.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 CEH13591.1 - 0.0085 16.4 0.6 0.46 10.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CEH13591.1 - 0.016 15.5 1.0 0.037 14.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 CEH13591.1 - 0.053 13.0 0.0 0.28 10.6 0.0 2.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 CEH13591.1 - 0.12 12.7 0.0 27 5.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 CEH13591.1 - 0.13 12.4 0.4 7.4 6.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 CEH13591.1 - 0.16 12.4 0.0 0.56 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEH13591.1 - 0.32 10.7 1.9 1 9.1 0.3 2.4 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 CEH13591.1 - 0.35 10.4 1.4 2.4 7.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Phage_holin_5_2 PF16079.5 CEH13591.1 - 2.6 8.4 6.7 0.56 10.6 0.7 2.8 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Aha1_N PF09229.11 CEH13593.1 - 1.1e-27 96.9 0.0 1.6e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal RNA_polI_A34 PF08208.11 CEH13593.1 - 0.045 13.8 3.5 0.061 13.4 3.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TMEM247 PF15444.6 CEH13593.1 - 0.17 11.9 1.1 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 247 Glyco_hydro_16 PF00722.21 CEH13594.1 - 1.8e-06 27.5 0.7 4.6e-06 26.2 0.0 2.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 Apt1 PF10351.9 CEH13594.1 - 5.7 5.7 6.7 0.2 10.5 0.8 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Homoserine_dh PF00742.19 CEH13595.1 - 1.4e-46 158.6 0.0 1.8e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CEH13595.1 - 5.7e-14 52.8 0.0 1.2e-13 51.7 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CEH13595.1 - 0.16 12.4 0.2 1.2 9.6 0.2 2.3 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ecl1 PF12855.7 CEH13596.1 - 0.00095 20.4 16.3 0.00095 20.4 16.3 2.9 3 0 0 3 3 3 1 ECL1/2/3 zinc binding proteins Apt1 PF10351.9 CEH13596.1 - 0.015 14.2 3.1 0.02 13.8 3.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain MGC-24 PF05283.11 CEH13596.1 - 0.21 12.0 22.4 6.1 7.3 22.4 2.6 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin BUD22 PF09073.10 CEH13596.1 - 0.6 9.4 4.3 1 8.6 4.3 1.3 1 0 0 1 1 1 0 BUD22 Podoplanin PF05808.11 CEH13596.1 - 1.2 9.2 20.8 5.5 7.1 20.8 2.0 1 1 0 1 1 1 0 Podoplanin DHHC PF01529.20 CEH13598.1 - 2.9e-05 24.2 0.0 5.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF2568 PF10823.8 CEH13598.1 - 0.12 12.7 3.5 0.38 11.1 3.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2568) Mt_ATP-synt_B PF05405.14 CEH13599.1 - 1.9e-44 151.2 6.3 2.2e-44 151.0 6.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ribosomal_S20p PF01649.18 CEH13599.1 - 1.3 9.7 9.1 1.6 9.4 1.4 2.2 1 1 1 2 2 2 0 Ribosomal protein S20 Glyco_hydro_43 PF04616.14 CEH13600.1 - 1.9e-20 73.4 7.5 7.2e-09 35.4 1.5 3.8 4 1 0 4 4 4 3 Glycosyl hydrolases family 43 Glyco_hydro_18 PF00704.28 CEH13602.1 - 5e-61 207.1 0.5 6.3e-61 206.8 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Macoilin PF09726.9 CEH13602.1 - 0.21 10.1 8.0 0.29 9.6 8.0 1.1 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 CEH13602.1 - 0.55 9.2 4.9 0.76 8.7 4.9 1.1 1 0 0 1 1 1 0 Mitoguardin NPR3 PF03666.13 CEH13602.1 - 0.68 8.7 6.8 0.97 8.2 6.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CEH13602.1 - 3.3 6.4 5.8 4.6 5.9 5.8 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CEH13602.1 - 5.7 5.7 9.7 7.8 5.2 9.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NST1 PF13945.6 CEH13602.1 - 7.5 6.6 9.9 12 5.9 9.9 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator RAP1 PF07218.11 CEH13602.1 - 8.4 4.5 10.8 12 4.1 10.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_hydro_38N PF01074.22 CEH13603.1 - 2.9e-74 250.1 0.1 4.1e-74 249.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CEH13603.1 - 4.1e-41 141.4 0.0 7.6e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CEH13603.1 - 8e-24 83.6 0.3 1.5e-23 82.7 0.3 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CEH13603.1 - 3.5e-09 36.6 0.0 8.7e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 CEH13603.1 - 0.00069 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Glyco_hydro_79C PF16862.5 CEH13605.1 - 2.2e-17 63.8 3.0 2.2e-17 63.8 3.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Shisa PF13908.6 CEH13605.1 - 0.0039 17.5 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.16 CEH13605.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 CEH13605.1 - 0.028 15.3 0.0 0.074 13.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Alpha_GJ PF03229.13 CEH13605.1 - 0.77 10.3 20.8 0.34 11.5 7.1 3.5 3 0 0 3 3 3 0 Alphavirus glycoprotein J FeoB_N PF02421.18 CEH13607.1 - 0.025 14.1 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B DnaJ PF00226.31 CEH13608.1 - 4.9e-15 55.4 0.6 9.9e-15 54.4 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain PNK3P PF08645.11 CEH13609.1 - 2.6e-45 154.0 0.0 1.2e-42 145.4 0.0 2.2 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CEH13609.1 - 3.2e-19 69.5 0.1 1.2e-08 35.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain KTI12 PF08433.10 CEH13609.1 - 0.042 13.3 1.0 1.7 8.0 1.0 2.2 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CEH13609.1 - 0.1 11.9 0.0 0.46 9.7 0.0 1.9 1 1 1 2 2 2 0 Zeta toxin CENP-B_dimeris PF09026.10 CEH13610.1 - 0.0052 17.2 4.1 0.013 15.8 4.1 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain NOA36 PF06524.12 CEH13610.1 - 0.29 10.4 6.2 0.55 9.5 6.2 1.4 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 CEH13610.1 - 1.1 9.6 3.9 2.6 8.5 3.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SPX PF03105.19 CEH13612.1 - 2.9 7.7 6.6 3.3 7.5 6.6 1.1 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 CEH13612.1 - 4.5 4.2 6.3 5.4 4.0 6.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Menin PF05053.13 CEH13612.1 - 7.2 4.8 11.2 9.2 4.5 11.2 1.1 1 0 0 1 1 1 0 Menin FMO-like PF00743.19 CEH13613.1 - 1.6e-18 66.5 0.0 1.1e-17 63.7 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CEH13613.1 - 1.5e-15 57.2 0.9 6.5e-12 45.3 0.9 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEH13613.1 - 2.9e-12 46.5 0.6 4.6e-09 36.0 0.3 3.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEH13613.1 - 2.4e-10 40.5 0.5 6.5e-08 32.5 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 CEH13613.1 - 1.1e-09 38.0 1.3 2.7e-07 30.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CEH13613.1 - 3e-08 33.8 2.3 2.8e-07 30.7 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 CEH13613.1 - 3.2e-06 26.6 2.0 0.021 14.1 0.5 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CEH13613.1 - 2.6e-05 24.7 7.5 0.009 16.6 1.1 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CEH13613.1 - 5e-05 23.4 0.2 0.33 11.0 0.1 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 CEH13613.1 - 6.2e-05 23.0 4.2 0.003 17.5 0.2 3.5 4 0 0 4 4 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 CEH13613.1 - 0.00084 18.7 0.1 0.025 13.9 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 CEH13613.1 - 0.0019 18.1 0.4 0.0019 18.1 0.4 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CEH13613.1 - 0.0031 17.9 0.0 0.79 10.2 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding HI0933_like PF03486.14 CEH13613.1 - 0.0095 14.7 4.2 0.27 9.9 1.0 2.4 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 CEH13613.1 - 0.013 14.6 6.3 0.16 11.0 1.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CEH13613.1 - 0.022 13.8 0.3 0.064 12.3 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 CEH13613.1 - 0.025 13.8 2.1 0.1 11.8 0.6 2.1 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 CEH13613.1 - 0.028 14.0 0.4 0.056 13.0 0.4 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 CEH13613.1 - 0.038 13.2 3.3 0.3 10.3 0.6 2.3 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.21 CEH13613.1 - 0.043 13.2 0.4 6.6 6.0 0.2 2.2 2 0 0 2 2 2 0 ThiF family FAD_binding_2 PF00890.24 CEH13613.1 - 0.16 11.0 9.0 0.041 13.0 2.5 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_2 PF03446.15 CEH13613.1 - 0.16 12.1 0.1 0.31 11.2 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Syntaxin_2 PF14523.6 CEH13614.1 - 6.9e-14 52.0 3.3 1.8e-12 47.5 0.7 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 CEH13614.1 - 3.6e-13 49.3 2.0 6.4e-13 48.5 0.3 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CEH13614.1 - 0.0016 18.2 2.1 0.0016 18.2 2.1 2.6 2 1 0 2 2 2 1 Syntaxin Spore_III_AB PF09548.10 CEH13614.1 - 0.024 14.7 2.3 0.068 13.3 0.1 2.6 2 2 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF2730 PF10805.8 CEH13614.1 - 0.14 12.3 1.0 0.68 10.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Synaptobrevin PF00957.21 CEH13614.1 - 0.18 11.6 0.6 0.8 9.5 0.0 2.4 2 1 1 3 3 3 0 Synaptobrevin Herpes_US9 PF06072.11 CEH13614.1 - 0.33 10.8 1.0 0.54 10.2 0.2 1.7 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 BRE1 PF08647.11 CEH13614.1 - 4.4 7.5 7.2 0.59 10.2 0.2 3.0 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF16 PF01519.16 CEH13614.1 - 7.3 7.1 8.1 4.3 7.9 0.3 3.0 1 1 1 3 3 3 0 Protein of unknown function DUF16 SHR3_chaperone PF08229.11 CEH13615.1 - 2.3e-38 131.1 0.0 2.8e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5527 PF17665.1 CEH13615.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) DUF2231 PF09990.9 CEH13615.1 - 0.26 11.8 3.9 1.3 9.5 1.4 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF1772 PF08592.11 CEH13615.1 - 0.31 11.3 5.5 2 8.7 5.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Glyco_hydro_15 PF00723.21 CEH13617.1 - 3.8e-49 167.7 0.0 1.8e-27 96.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 Bin3 PF06859.12 CEH13620.1 - 7.9e-26 90.8 0.0 1.6e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 CEH13620.1 - 2.1e-09 37.3 0.0 5.7e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH13620.1 - 4.7e-07 30.5 0.0 7.2e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH13620.1 - 6.5e-07 30.0 0.1 6.8e-06 26.7 0.0 2.6 1 1 2 3 3 3 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEH13620.1 - 7.6e-05 22.2 0.0 0.0016 17.9 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_11 PF08241.12 CEH13620.1 - 0.00032 21.3 0.0 0.0017 19.0 0.0 2.1 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH13620.1 - 0.0005 19.9 0.0 0.00076 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEH13620.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 CEH13620.1 - 0.081 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Metallophos PF00149.28 CEH13621.1 - 2.4e-27 96.8 0.0 7.9e-27 95.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CEH13621.1 - 4.7e-22 78.1 0.0 1.3e-21 76.7 0.0 1.7 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 CEH13621.1 - 1e-14 53.6 1.1 0.0018 18.0 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEH13621.1 - 9e-09 34.8 3.8 0.017 15.2 0.0 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEH13621.1 - 2.6e-06 27.0 3.7 0.0026 17.4 0.0 3.9 6 0 0 6 6 6 2 TPR repeat TPR_8 PF13181.6 CEH13621.1 - 0.0004 20.4 0.4 8.5 6.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEH13621.1 - 0.0018 18.5 0.2 0.17 12.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEH13621.1 - 0.022 15.6 0.3 7.4 7.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEH13621.1 - 0.035 14.8 0.5 0.16 12.7 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEH13621.1 - 0.17 12.1 0.2 2.9 8.1 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF2408 PF10303.9 CEH13622.1 - 8.5e-51 172.1 2.3 3e-36 124.9 0.0 4.8 3 2 0 4 4 4 3 Protein of unknown function (DUF2408) HCR PF07111.12 CEH13622.1 - 0.048 11.7 0.5 0.086 10.9 0.5 1.3 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) BUD22 PF09073.10 CEH13622.1 - 0.78 9.0 6.5 1.5 8.0 6.5 1.4 1 0 0 1 1 1 0 BUD22 DUF1664 PF07889.12 CEH13622.1 - 1.2 9.1 3.2 1.7 8.7 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4455 PF14643.6 CEH13622.1 - 8 5.0 6.9 3.6 6.1 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4455) Pkinase PF00069.25 CEH13623.1 - 4e-55 187.0 0.0 5.4e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH13623.1 - 6.5e-19 68.2 0.0 1.2e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEH13623.1 - 0.0035 17.3 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CEH13623.1 - 0.013 15.2 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Serinc PF03348.15 CEH13624.1 - 6.1e-147 490.0 0.1 7.1e-147 489.8 0.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Ribosomal_S8 PF00410.19 CEH13627.1 - 1.9e-09 37.5 0.0 4.6e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S4e PF00900.20 CEH13628.1 - 1.8e-32 111.0 0.2 4.9e-32 109.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CEH13628.1 - 6.2e-23 80.2 1.3 7.5e-23 79.9 0.0 1.8 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CEH13628.1 - 3.4e-20 71.8 5.4 6.2e-20 71.0 5.4 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 CEH13628.1 - 9.1e-05 22.1 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 CEH13628.1 - 0.00037 20.4 4.4 0.0015 18.5 4.4 2.1 1 0 0 1 1 1 1 KOW motif CwfJ_C_2 PF04676.14 CEH13629.1 - 3.6e-30 104.8 0.1 3.6e-30 104.8 0.1 3.1 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 CEH13629.1 - 9.5e-29 99.7 0.1 1.5e-28 99.1 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF410 PF04190.13 CEH13631.1 - 1.3e-50 172.6 0.0 3.9e-50 171.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF410) TPR_14 PF13428.6 CEH13631.1 - 0.051 14.4 0.4 0.33 11.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S49 PF01343.18 CEH13632.1 - 5.5e-45 153.1 0.0 1.4e-28 99.8 0.0 2.6 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.23 CEH13632.1 - 0.0043 17.0 0.1 0.023 14.6 0.0 2.1 2 0 0 2 2 2 1 Clp protease Glyco_trans_4_4 PF13579.6 CEH13633.1 - 1.7e-07 31.8 7.3 1.7e-07 31.8 7.3 2.8 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 CEH13633.1 - 6.1e-06 26.7 0.0 1.5e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CEH13633.1 - 6.8e-05 23.2 0.0 0.00028 21.2 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CEH13633.1 - 0.0014 18.6 3.0 0.0032 17.5 3.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CEH13633.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 BST2 PF16716.5 CEH13637.1 - 2.2 8.9 7.2 4.8 7.8 0.4 3.4 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 Actin PF00022.19 CEH13638.1 - 2.9e-18 65.7 0.0 3.6e-08 32.4 0.0 2.5 3 0 0 3 3 3 2 Actin Actin_micro PF17003.5 CEH13638.1 - 2.2e-07 30.4 0.1 0.00034 19.9 0.1 2.3 2 0 0 2 2 2 2 Putative actin-like family Aminotran_1_2 PF00155.21 CEH13639.1 - 6.7e-18 65.0 0.0 8.8e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CEH13639.1 - 0.00045 19.1 0.0 0.0018 17.2 0.0 1.9 1 1 1 2 2 2 1 Alanine-glyoxylate amino-transferase zf-C2H2_aberr PF17017.5 CEH13640.1 - 9.5e-08 32.4 1.1 0.012 15.8 0.1 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 CEH13640.1 - 0.013 15.9 10.4 0.42 11.2 0.3 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEH13640.1 - 0.22 12.0 3.5 8.6 7.0 1.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEH13640.1 - 2 9.4 13.4 11 7.2 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Lon_C PF05362.13 CEH13643.1 - 1.2e-62 211.1 0.0 1.9e-62 210.5 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CEH13643.1 - 1.6e-23 83.5 0.0 3.9e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEH13643.1 - 1.2e-09 38.2 0.0 3.4e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 CEH13643.1 - 3.7e-08 33.2 0.0 8.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase LON_substr_bdg PF02190.16 CEH13643.1 - 4.2e-08 33.3 0.0 7.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_22 PF13401.6 CEH13643.1 - 1.9e-05 24.9 0.2 0.0028 17.9 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEH13643.1 - 8.3e-05 23.0 0.1 8.3e-05 23.0 0.1 3.1 3 1 1 4 4 3 1 AAA ATPase domain AAA_2 PF07724.14 CEH13643.1 - 0.0016 18.6 0.0 0.0059 16.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CEH13643.1 - 0.0024 17.3 0.0 0.0072 15.7 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CEH13643.1 - 0.0059 16.4 0.1 0.022 14.5 0.1 1.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 CEH13643.1 - 0.0061 16.4 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CEH13643.1 - 0.0095 16.1 0.0 0.0095 16.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CEH13643.1 - 0.013 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CEH13643.1 - 0.013 15.0 0.0 0.039 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CEH13643.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TniB PF05621.11 CEH13643.1 - 0.017 14.5 0.1 3.3 7.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein AAA_7 PF12775.7 CEH13643.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CEH13643.1 - 0.037 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_PrkA PF08298.11 CEH13643.1 - 0.039 12.9 0.0 0.75 8.6 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_23 PF13476.6 CEH13643.1 - 0.062 13.8 9.3 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CEH13643.1 - 0.075 13.6 0.0 0.075 13.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CEH13643.1 - 0.084 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CEH13643.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 CEH13643.1 - 0.088 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 CEH13643.1 - 0.093 12.6 0.1 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 CEH13643.1 - 0.097 12.4 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 CEH13643.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Rad17 PF03215.15 CEH13643.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 CEH13643.1 - 1.1 9.8 4.4 0.44 11.1 0.1 2.4 2 1 1 3 3 2 0 ABC transporter M PF02370.16 CEH13643.1 - 3.9 8.4 7.5 29 5.7 0.6 3.4 2 0 0 2 2 2 0 M protein repeat Pro_CA PF00484.19 CEH13644.1 - 4.9e-39 134.1 0.1 6.9e-39 133.6 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.20 CEH13644.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2922 PF11148.8 CEH13644.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) HEAT_2 PF13646.6 CEH13645.1 - 0.0001 22.6 11.5 0.005 17.2 0.0 6.1 5 1 4 9 9 9 4 HEAT repeats HEAT PF02985.22 CEH13645.1 - 0.00023 21.2 1.0 6.5 7.3 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat SIKE PF05769.11 CEH13645.1 - 0.0067 16.4 3.4 0.1 12.5 0.2 2.5 2 0 0 2 2 2 1 SIKE family MCD_N PF17408.2 CEH13645.1 - 0.041 14.0 0.6 0.22 11.7 0.1 2.6 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain MutS_II PF05188.17 CEH13645.1 - 0.051 13.9 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 MutS domain II HEAT_EZ PF13513.6 CEH13645.1 - 1.2 9.7 7.5 51 4.5 0.2 4.9 4 1 1 5 5 5 0 HEAT-like repeat MFS_1 PF07690.16 CEH13646.1 - 3.8e-15 55.7 24.7 1e-14 54.3 24.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 CEH13646.1 - 9.2e-11 41.7 1.0 2.6e-10 40.2 1.0 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 FMO-like PF00743.19 CEH13647.1 - 8.5e-11 41.0 0.2 1.2e-09 37.1 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CEH13647.1 - 2.4e-09 36.9 0.1 1.1e-08 34.7 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEH13647.1 - 2.6e-07 30.2 0.2 4.5e-05 22.8 0.0 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEH13647.1 - 1.4e-06 28.4 0.0 0.00013 22.1 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CEH13647.1 - 1.4e-06 27.7 0.1 5.1e-05 22.6 0.0 2.6 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CEH13647.1 - 1.5e-06 28.1 0.1 0.01 15.5 0.0 3.5 4 1 0 5 5 5 2 FAD dependent oxidoreductase Thi4 PF01946.17 CEH13647.1 - 1.2e-05 24.7 0.1 0.0065 15.7 0.0 2.6 3 0 0 3 3 3 2 Thi4 family Pyr_redox PF00070.27 CEH13647.1 - 4.4e-05 23.9 0.8 0.61 10.7 0.0 3.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 CEH13647.1 - 0.0018 16.9 0.0 0.12 10.9 0.0 2.2 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 CEH13647.1 - 0.0078 15.5 0.0 0.46 9.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 CEH13647.1 - 0.013 15.5 0.0 0.27 11.3 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 CEH13647.1 - 0.016 14.3 0.2 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CEH13647.1 - 0.02 14.0 0.1 0.21 10.6 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.6 CEH13647.1 - 0.18 12.2 0.0 0.97 9.9 0.0 2.2 3 0 0 3 3 3 0 Putative NAD(P)-binding Ras PF00071.22 CEH13648.1 - 6.4e-54 181.9 0.0 7.4e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH13648.1 - 4.2e-31 107.7 0.0 5.3e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH13648.1 - 1.4e-14 53.9 0.0 2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEH13648.1 - 8.4e-06 25.8 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEH13648.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CEH13648.1 - 0.0052 16.5 0.1 0.0081 15.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 CEH13648.1 - 0.0077 15.6 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEH13648.1 - 0.014 14.8 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CEH13648.1 - 0.087 13.2 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CEH13648.1 - 0.18 11.7 0.0 1 9.2 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Mito_carr PF00153.27 CEH13650.1 - 6.6e-61 202.3 3.6 6e-23 80.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CEH13650.1 - 0.00055 20.3 6.2 0.52 10.7 0.0 3.2 2 1 1 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family V4R PF02830.18 CEH13650.1 - 0.25 11.4 0.8 1.4 9.0 0.0 2.4 3 0 0 3 3 3 0 V4R domain Bacteriocin_IIc PF10439.9 CEH13650.1 - 0.25 11.5 3.1 4.5 7.5 0.0 3.3 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Serine_protease PF18405.1 CEH13650.1 - 3 6.9 7.3 21 4.2 0.0 3.9 3 1 1 4 4 4 0 Gammaproteobacterial serine protease Romo1 PF10247.9 CEH13650.1 - 7.3 7.0 7.0 7.1 7.1 0.1 3.6 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 SQS_PSY PF00494.19 CEH13651.1 - 8e-52 176.3 2.9 1.2e-51 175.8 2.9 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF4131 PF13567.6 CEH13651.1 - 3.1 7.4 7.0 0.57 9.8 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) D-ser_dehydrat PF14031.6 CEH13652.1 - 8.2e-18 64.9 0.1 5.1e-17 62.3 0.0 2.4 2 1 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CEH13652.1 - 1e-11 44.9 0.1 3e-11 43.4 0.1 1.7 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Metallophos PF00149.28 CEH13653.1 - 1.2e-13 52.0 0.0 3e-12 47.5 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ORC2 PF04084.14 CEH13654.1 - 7.9e-31 107.2 0.0 1.3e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 UxaE PF16257.5 CEH13654.1 - 0.056 12.1 0.0 0.085 11.5 0.0 1.1 1 0 0 1 1 1 0 tagaturonate epimerase AT_hook PF02178.19 CEH13654.1 - 2.1 8.5 28.6 0.1 12.6 1.8 4.3 4 0 0 4 4 4 0 AT hook motif PHF5 PF03660.14 CEH13655.1 - 2.7e-31 107.9 2.9 1.1e-24 86.6 2.4 2.0 1 1 1 2 2 2 2 PHF5-like protein Sec1 PF00995.23 CEH13656.1 - 1.5e-122 410.8 0.0 1.8e-122 410.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family FUN14 PF04930.15 CEH13657.1 - 4.8e-22 78.2 1.7 5.9e-22 77.9 1.7 1.1 1 0 0 1 1 1 1 FUN14 family Ntox47 PF15540.6 CEH13657.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 2 0 0 2 2 2 0 Bacterial toxin 47 GST_N_2 PF13409.6 CEH13658.1 - 6.5e-19 68.0 0.0 1.5e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEH13658.1 - 4.2e-14 52.3 0.0 8.4e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEH13658.1 - 3.7e-08 33.5 0.0 6.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEH13658.1 - 3.2e-06 27.2 0.1 6.9e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CEH13658.1 - 0.0097 16.3 0.0 4.6 7.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain tRNA-synt_1d PF00750.19 CEH13659.1 - 1.4e-94 316.9 1.4 1.9e-94 316.5 1.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CEH13659.1 - 1.6e-21 76.7 0.1 3.5e-21 75.6 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain POT1 PF02765.17 CEH13659.1 - 0.11 12.3 0.0 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 Methyltransf_25 PF13649.6 CEH13660.1 - 3.3e-09 37.3 0.0 3.2e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH13660.1 - 2.5e-06 27.4 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH13660.1 - 0.00016 22.4 0.0 0.0011 19.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH13660.1 - 0.00029 21.4 0.0 0.00082 20.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH13660.1 - 0.0096 15.7 0.1 0.042 13.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEH13660.1 - 0.011 15.2 0.0 0.046 13.2 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.19 CEH13660.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1752 PF08550.10 CEH13661.1 - 2.5e-11 43.2 4.8 2.5e-11 43.2 4.8 2.1 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1752) RRN3 PF05327.11 CEH13661.1 - 0.67 8.4 6.7 1.1 7.8 6.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nucleo_P87 PF07267.11 CEH13661.1 - 8.3 5.1 6.0 14 4.4 6.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 tRNA-synt_2 PF00152.20 CEH13663.1 - 7.3e-62 209.2 0.0 3e-51 174.4 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) ThiF PF00899.21 CEH13667.1 - 3.4e-104 347.5 0.0 5.5e-70 235.5 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CEH13667.1 - 6.1e-93 311.4 0.2 1.1e-92 310.5 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 CEH13667.1 - 4.3e-33 113.3 0.2 1.2e-32 111.9 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 CEH13667.1 - 4.1e-28 97.9 0.0 8.8e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 CEH13667.1 - 1.1e-23 83.2 0.1 2.7e-23 81.9 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Ribosomal_L33 PF00471.20 CEH13668.1 - 9.3e-10 38.8 0.1 1e-09 38.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 DUF1729 PF08354.10 CEH13668.1 - 0.0072 15.3 0.1 0.0072 15.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MGS PF02142.22 CEH13668.1 - 0.1 12.8 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 MGS-like domain UCH PF00443.29 CEH13670.1 - 4.3e-41 141.1 0.0 8.1e-41 140.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEH13670.1 - 2.1e-09 37.4 0.0 2.4e-08 34.0 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Arginosuc_synth PF00764.19 CEH13671.1 - 1.2e-152 508.8 0.0 1.4e-152 508.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CEH13671.1 - 0.0006 19.4 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CEH13671.1 - 0.045 12.5 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Aminotran_3 PF00202.21 CEH13672.1 - 1.1e-79 268.0 0.0 1.5e-79 267.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CEH13672.1 - 0.00065 19.0 0.0 0.00092 18.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CEH13672.1 - 0.013 14.3 0.0 0.04 12.7 0.0 1.7 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Thiolase_N PF00108.23 CEH13673.1 - 9.3e-78 261.2 0.3 1.1e-77 260.9 0.3 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEH13673.1 - 3.3e-40 136.5 2.6 4.9e-40 136.0 0.4 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEH13673.1 - 0.00053 19.6 0.9 0.0012 18.5 0.9 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Rsa3 PF14615.6 CEH13674.1 - 1e-12 47.4 0.0 1.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 NST1 PF13945.6 CEH13674.1 - 0.042 14.0 8.5 0.056 13.6 8.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Het-C PF07217.11 CEH13674.1 - 0.36 9.3 1.9 0.46 8.9 1.9 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C SOBP PF15279.6 CEH13674.1 - 0.86 10.2 4.1 0.99 10.0 4.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1771 PF08590.10 CEH13675.1 - 1.3e-22 80.0 7.1 1.3e-22 80.0 7.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 CEH13675.1 - 1.1e-12 48.1 0.7 1.1e-12 48.1 0.7 2.4 3 0 0 3 3 3 1 Smr domain DUF4407 PF14362.6 CEH13675.1 - 0.014 14.8 6.4 0.019 14.4 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dishevelled PF02377.15 CEH13675.1 - 0.33 11.4 2.9 0.64 10.4 2.9 1.4 1 0 0 1 1 1 0 Dishevelled specific domain Chorion_3 PF05387.11 CEH13675.1 - 2.2 7.9 12.5 0.26 10.9 4.9 2.2 2 0 0 2 2 2 0 Chorion family 3 DUF2828 PF11443.8 CEH13676.1 - 1.2e-126 423.4 0.0 2.7e-112 376.0 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) MLVIN_C PF18697.1 CEH13676.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Ribosomal_S2 PF00318.20 CEH13678.1 - 5.1e-51 172.9 0.0 1.5e-50 171.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S2 SIS_2 PF13580.6 CEH13678.1 - 0.0027 17.7 0.0 0.27 11.3 0.0 2.8 2 0 0 2 2 2 1 SIS domain DUF3721 PF12518.8 CEH13678.1 - 0.015 15.1 0.0 0.05 13.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function HrpA_pilin PF09589.10 CEH13678.1 - 0.4 11.4 7.0 0.19 12.4 1.5 2.6 2 0 0 2 2 2 0 HrpA pilus formation protein DUF3435 PF11917.8 CEH13679.1 - 2.3 7.0 9.1 2.6 6.9 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF4407 PF14362.6 CEH13679.1 - 4.2 6.6 9.4 5 6.4 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 CEH13679.1 - 4.7 7.1 11.7 0.75 9.6 1.7 2.2 1 1 1 2 2 2 0 Septum formation initiator CENP-K PF11802.8 CEH13679.1 - 7.6 6.0 11.3 21 4.6 8.0 1.9 1 1 1 2 2 2 0 Centromere-associated protein K TAF8_C PF10406.9 CEH13679.1 - 9 7.0 7.2 1.8 9.2 1.2 2.3 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Kinesin PF00225.23 CEH13680.1 - 9e-96 320.7 0.1 1e-95 320.5 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEH13680.1 - 2.3e-34 118.5 0.0 4.5e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 CEH13680.1 - 0.051 13.8 0.1 0.13 12.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain UpxZ PF06603.11 CEH13680.1 - 0.16 12.3 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists ADH_N_2 PF16884.5 CEH13681.1 - 1.5e-26 92.4 0.1 6e-26 90.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 CEH13681.1 - 1.6e-09 37.8 0.0 3.3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEH13681.1 - 0.00024 22.1 0.0 0.0017 19.4 0.0 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 CEH13681.1 - 0.0059 16.1 0.0 0.0083 15.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 CEH13681.1 - 0.042 13.3 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mito_carr PF00153.27 CEH13683.1 - 6e-42 141.5 1.0 2.9e-19 68.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_Me_trans PF04252.13 CEH13684.1 - 3.9e-54 183.3 0.0 8.3e-54 182.2 0.0 1.5 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase UDG PF03167.19 CEH13685.1 - 0.022 14.7 0.0 0.57 10.2 0.0 2.1 1 1 0 2 2 2 0 Uracil DNA glycosylase superfamily 5-FTHF_cyc-lig PF01812.20 CEH13686.1 - 6.5e-21 75.0 0.0 8.4e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Flg_hook PF02120.16 CEH13687.1 - 0.059 13.3 0.3 0.063 13.2 0.3 1.1 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK DUF3818 PF12825.7 CEH13688.1 - 1.3e-57 195.4 0.0 2.6e-57 194.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CEH13688.1 - 1.1e-29 103.0 0.3 2.2e-29 102.1 0.3 1.5 1 0 0 1 1 1 1 PX-associated Zn_clus PF00172.18 CEH13689.1 - 2.2e-08 34.1 9.2 3.7e-08 33.4 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MRG PF05712.13 CEH13690.1 - 1.2e-60 204.3 0.0 1.5e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CEH13690.1 - 6e-11 42.1 0.1 1.3e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.17 CEH13690.1 - 0.0085 16.5 0.1 0.025 15.0 0.1 1.7 1 0 0 1 1 1 1 PWWP domain Chromo PF00385.24 CEH13690.1 - 0.047 13.6 1.3 0.13 12.2 1.3 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TAF4 PF05236.14 CEH13690.1 - 0.14 11.9 4.9 0.25 11.1 4.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Shadoo PF14999.6 CEH13690.1 - 0.19 11.8 14.7 0.026 14.6 7.1 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF5558 PF17713.1 CEH13692.1 - 0.12 12.8 3.3 0.16 12.4 3.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5558) DUF1691 PF07950.11 CEH13693.1 - 3.2e-08 34.2 1.0 1.1e-07 32.6 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1691) DUF498 PF04430.14 CEH13694.1 - 0.0002 21.4 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DUF3446 PF11928.8 CEH13694.1 - 0.11 12.8 6.3 0.25 11.7 6.3 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain DnaJ PF00226.31 CEH13695.1 - 6e-11 42.3 0.0 9.6e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Syntaxin PF00804.25 CEH13696.1 - 1.3e-31 109.8 12.2 2.2e-31 109.1 12.2 1.3 1 0 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 CEH13696.1 - 0.00014 22.2 14.2 0.00019 21.7 8.2 2.4 2 0 0 2 2 2 1 Syntaxin-like protein BLOC1_2 PF10046.9 CEH13696.1 - 0.012 15.9 10.7 0.58 10.5 0.6 3.3 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMCO5 PF14992.6 CEH13696.1 - 0.044 13.4 12.2 0.017 14.7 6.4 2.0 2 0 0 2 2 2 0 TMCO5 family SNARE PF05739.19 CEH13696.1 - 0.064 13.3 0.5 0.064 13.3 0.5 2.5 3 0 0 3 3 3 0 SNARE domain Allexi_40kDa PF05549.11 CEH13696.1 - 0.09 12.3 6.6 0.063 12.8 1.3 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Tht1 PF04163.12 CEH13696.1 - 0.12 11.1 1.7 0.098 11.4 0.2 1.5 2 0 0 2 2 2 0 Tht1-like nuclear fusion protein CdvA PF18822.1 CEH13696.1 - 0.12 12.2 8.1 0.53 10.1 1.7 2.8 2 1 0 2 2 2 0 CdvA-like coiled-coil domain IL11 PF07400.11 CEH13696.1 - 0.14 11.8 2.4 2 8.1 0.2 2.2 2 0 0 2 2 2 0 Interleukin 11 Spectrin PF00435.21 CEH13696.1 - 0.2 12.1 7.3 0.28 11.7 1.3 2.6 2 0 0 2 2 2 0 Spectrin repeat Gp-FAR-1 PF05823.12 CEH13696.1 - 0.24 11.8 5.3 0.14 12.5 2.6 2.0 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Vac_Fusion PF02346.16 CEH13696.1 - 0.36 10.5 3.6 7.3 6.3 0.2 3.2 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Baculo_PEP_C PF04513.12 CEH13696.1 - 0.52 10.3 12.5 0.51 10.4 4.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 CEH13696.1 - 1.3 9.3 11.3 1.5 9.1 3.8 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 CEH13696.1 - 1.9 6.9 9.0 0.15 10.6 2.4 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 CEH13696.1 - 2.7 8.2 13.0 2.9 8.1 1.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 CEH13696.1 - 3.9 5.3 8.4 0.74 7.7 3.3 1.8 2 0 0 2 2 2 0 Prominin Syntaxin-6_N PF09177.11 CEH13696.1 - 4.3 7.9 10.6 3.1 8.4 4.3 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF16 PF01519.16 CEH13696.1 - 4.5 7.8 17.2 0.18 12.3 2.0 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 Herpes_UL25 PF01499.16 CEH13696.1 - 7.1 5.0 12.3 0.66 8.4 4.8 2.1 1 1 1 2 2 2 0 Herpesvirus UL25 family Cauli_AT PF03233.13 CEH13696.1 - 8 6.4 8.5 16 5.4 2.3 2.5 2 1 0 2 2 2 0 Aphid transmission protein DUF2203 PF09969.9 CEH13696.1 - 8.1 7.2 12.2 7.9 7.2 2.1 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) PIN_8 PF18476.1 CEH13696.1 - 8.5 6.2 14.1 3.2 7.6 7.7 2.3 1 1 1 2 2 2 0 PIN like domain tRNA-synt_2 PF00152.20 CEH13697.1 - 6.4e-77 258.7 0.0 8.8e-77 258.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEH13697.1 - 2.5e-13 49.8 0.0 6.2e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CEH13697.1 - 4.4e-08 32.9 0.0 0.00019 21.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ribosomal_60s PF00428.19 CEH13697.1 - 0.92 10.1 15.1 16 6.2 0.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein LIP PF03583.14 CEH13698.1 - 5.8e-55 186.6 0.0 8.5e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase DcpS PF05652.12 CEH13699.1 - 3.4e-25 88.9 0.0 6.3e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 CEH13699.1 - 2.5e-24 85.9 0.0 4e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CEH13699.1 - 0.12 13.2 1.2 0.75 10.6 1.2 2.2 1 1 0 1 1 1 0 HIT domain DPPIV_N PF00930.21 CEH13700.1 - 1.8e-82 276.9 0.0 2.8e-82 276.3 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CEH13700.1 - 6.9e-45 153.1 0.4 1.1e-44 152.4 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 CEH13700.1 - 0.024 13.3 0.0 0.062 12.0 0.0 1.7 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) BLOC1S3 PF15753.5 CEH13700.1 - 0.058 13.5 1.0 0.1 12.7 1.0 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 MPP6 PF10175.9 CEH13701.1 - 0.0001 22.8 11.2 0.00059 20.3 8.3 2.8 2 1 0 2 2 2 1 M-phase phosphoprotein 6 Nucleo_P87 PF07267.11 CEH13701.1 - 0.016 14.1 11.3 0.025 13.5 11.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MSP1a PF11670.8 CEH13701.1 - 3.6 6.8 10.0 1.3 8.2 5.1 2.2 1 1 1 2 2 2 0 Major surface protein 1a (MSP1a) E1-E2_ATPase PF00122.20 CEH13702.1 - 3.7e-30 104.8 0.0 1.2e-29 103.2 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 CEH13702.1 - 3.8e-26 91.6 0.0 1.1e-25 90.2 0.0 1.8 1 1 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 CEH13702.1 - 8.6e-21 75.2 0.0 5.4e-12 46.5 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEH13702.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 CEH13702.1 - 5.9e-05 22.9 6.2 0.00013 21.7 6.2 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 CEH13702.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEH13702.1 - 0.014 15.2 0.0 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FliJ PF02050.16 CEH13705.1 - 0.0035 17.6 4.7 0.0035 17.6 4.7 2.7 1 1 1 2 2 2 1 Flagellar FliJ protein EPOP PF15223.6 CEH13705.1 - 0.035 13.5 7.5 0.048 13.0 7.5 1.1 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein TetR_C_13 PF16925.5 CEH13705.1 - 0.069 13.1 0.1 0.22 11.5 0.1 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain FAM76 PF16046.5 CEH13705.1 - 1.7 7.9 11.8 1.8 7.8 10.9 1.5 1 1 0 1 1 1 0 FAM76 protein SYCE1 PF15233.6 CEH13705.1 - 3.5 7.7 12.7 0.27 11.3 5.3 2.4 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF4200 PF13863.6 CEH13705.1 - 7.8 6.9 18.6 5.5 7.4 13.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Tropomyosin PF00261.20 CEH13705.1 - 9.9 5.4 25.0 6.9 6.0 7.7 3.1 1 1 1 3 3 3 0 Tropomyosin Zn_ribbon_recom PF13408.6 CEH13710.1 - 0.0034 17.9 0.6 0.0066 16.9 0.6 1.4 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain OTU PF02338.19 CEH13710.1 - 0.0049 17.4 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease DUF348 PF03990.14 CEH13710.1 - 0.081 12.7 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain DUF543 PF04418.12 CEH13710.1 - 0.28 11.2 1.1 0.67 10.0 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Kelch_4 PF13418.6 CEH13711.1 - 1e-20 73.5 1.7 1.5e-05 24.9 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CEH13711.1 - 2.3e-19 69.2 1.9 1.8e-05 24.9 0.0 6.7 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CEH13711.1 - 6.7e-10 38.7 0.2 0.0048 16.9 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CEH13711.1 - 1.1e-08 34.5 0.0 0.034 13.7 0.0 5.4 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 CEH13711.1 - 2.5e-08 33.9 0.3 0.011 16.0 0.0 4.9 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CEH13711.1 - 0.00054 19.8 0.9 0.33 11.0 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Acetyltransf_1 PF00583.25 CEH13712.1 - 5e-16 59.0 0.0 8.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CEH13712.1 - 1.4e-09 37.7 0.1 2.4e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CEH13712.1 - 2.3e-09 37.3 0.0 3.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEH13712.1 - 4.3e-09 36.7 0.0 7.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CEH13712.1 - 3.4e-06 26.8 0.1 1.7e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CEH13712.1 - 6.8e-06 26.8 0.0 8.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CEH13712.1 - 8.4e-05 22.6 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CEH13712.1 - 0.17 12.0 0.1 0.31 11.2 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Catalase PF00199.19 CEH13713.1 - 1.3e-161 538.0 0.0 1.7e-161 537.6 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CEH13713.1 - 3.1e-13 49.7 0.0 7.2e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Exo84_C PF16528.5 CEH13714.1 - 1e-52 179.0 0.0 1.4e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Exocyst component 84 C-terminal GCP_C_terminal PF04130.13 CEH13715.1 - 7.6e-21 74.9 0.0 9.2e-12 45.0 0.0 2.7 2 1 0 2 2 2 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CEH13715.1 - 1.2e-07 31.7 0.0 3.9e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal F-box PF00646.33 CEH13715.1 - 0.39 10.7 2.4 1.9 8.4 0.3 2.5 2 0 0 2 2 2 0 F-box domain DUF4407 PF14362.6 CEH13715.1 - 1.7 8.0 7.7 4.7 6.5 7.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sox17_18_mid PF12067.8 CEH13716.1 - 0.005 16.9 0.1 0.017 15.1 0.1 1.9 1 0 0 1 1 1 1 Sox 17/18 central domain NICE-1 PF15845.5 CEH13716.1 - 0.023 15.5 4.7 0.039 14.7 0.0 3.0 2 1 0 2 2 2 0 Cysteine-rich C-terminal 1 family Actin PF00022.19 CEH13717.1 - 3.9e-129 430.8 0.0 6.4e-128 426.8 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CEH13717.1 - 0.026 13.3 0.0 3.3 6.5 0.0 2.7 2 1 0 2 2 2 0 MreB/Mbl protein Pkinase PF00069.25 CEH13718.1 - 6.2e-61 206.1 0.0 6.7e-37 127.3 0.0 3.8 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CEH13718.1 - 1.1e-27 97.0 0.0 1.5e-15 57.2 0.0 4.0 3 1 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 CEH13718.1 - 2.6e-26 92.7 0.0 2.6e-26 92.7 0.0 1.7 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs RWD PF05773.22 CEH13718.1 - 8.2e-12 45.4 0.0 1.7e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 CEH13718.1 - 8.7e-07 28.5 0.0 8.7e-07 28.5 0.0 2.8 3 0 0 3 3 3 1 Histidyl-tRNA synthetase APH PF01636.23 CEH13718.1 - 0.00056 19.9 0.0 0.00056 19.9 0.0 3.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family HGTP_anticodon PF03129.20 CEH13718.1 - 0.00058 19.9 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Kinase-like PF14531.6 CEH13718.1 - 0.0037 16.6 0.1 0.07 12.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CEH13718.1 - 0.0039 16.8 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CEH13718.1 - 0.021 13.8 0.0 0.021 13.8 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 CEH13718.1 - 0.026 14.2 0.1 0.086 12.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 CEH13718.1 - 0.1 11.4 3.2 0.11 11.3 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase VCBS PF13517.6 CEH13719.1 - 1.3e-24 86.5 7.4 2.7e-07 31.0 0.8 5.8 4 2 2 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CEH13719.1 - 4.7e-07 29.8 20.4 0.0009 19.3 0.0 6.5 6 0 0 6 6 6 2 FG-GAP repeat TcdB_toxin_midN PF12256.8 CEH13719.1 - 0.0001 21.8 4.5 25 4.2 0.1 6.0 4 2 2 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region CoA_transf_3 PF02515.17 CEH13720.1 - 4.7e-60 203.7 0.0 1.2e-59 202.4 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III adh_short_C2 PF13561.6 CEH13721.1 - 1.2e-12 47.9 0.0 1.4e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH13721.1 - 3.4e-12 46.2 0.0 4.3e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH13721.1 - 0.038 13.9 0.0 0.062 13.2 0.0 1.4 1 1 0 1 1 1 0 KR domain AhpC-TSA_2 PF13911.6 CEH13722.1 - 6.4e-13 48.8 0.0 8.8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 CEH13722.1 - 0.00023 20.9 0.0 0.00045 19.9 0.0 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CEH13722.1 - 0.00032 20.6 0.0 0.0026 17.7 0.0 2.0 1 1 0 1 1 1 1 AhpC/TSA family Cytochrom_C PF00034.21 CEH13723.1 - 6.9e-11 43.2 0.0 1e-10 42.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CEH13723.1 - 2.9e-08 33.9 1.9 3.2e-07 30.6 1.9 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CEH13723.1 - 0.0028 17.4 0.8 0.014 15.1 0.8 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 CEH13723.1 - 0.0061 17.2 0.0 0.0065 17.1 0.0 1.1 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase Asn_synthase PF00733.21 CEH13724.1 - 4e-12 46.5 0.6 2.8e-05 23.9 0.1 2.3 2 1 0 2 2 2 2 Asparagine synthase RTA1 PF04479.13 CEH13725.1 - 6.9e-48 163.0 6.8 9.1e-48 162.6 6.8 1.2 1 0 0 1 1 1 1 RTA1 like protein CRAL_TRIO PF00650.20 CEH13726.1 - 1.4e-30 106.1 0.1 2.3e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEH13726.1 - 7e-10 38.9 0.6 7e-10 38.9 0.6 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CEH13726.1 - 0.0029 17.8 0.0 0.0049 17.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MFS_1 PF07690.16 CEH13727.1 - 1.6e-23 83.2 39.5 6.3e-14 51.7 10.1 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH13727.1 - 2.2e-08 33.4 2.1 2.2e-08 33.4 2.1 3.3 1 1 2 3 3 3 2 Sugar (and other) transporter DUF2380 PF09533.10 CEH13728.1 - 0.064 12.9 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) NodZ PF05830.11 CEH13728.1 - 0.08 11.7 0.2 0.08 11.7 0.2 1.0 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Cyclin_N PF00134.23 CEH13729.1 - 1.2e-43 147.8 0.1 3.5e-42 143.2 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEH13729.1 - 4.5e-31 107.4 0.2 7.8e-31 106.6 0.2 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF1971 PF09313.11 CEH13731.1 - 0.13 12.3 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) Ribosomal_S8e PF01201.22 CEH13732.1 - 2.1e-52 176.9 1.4 2.6e-52 176.7 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Zip PF02535.22 CEH13733.1 - 1.1e-30 107.0 4.3 2.5e-30 105.8 4.3 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter ETF PF01012.21 CEH13734.1 - 2.5e-45 154.6 3.5 4.5e-45 153.8 3.5 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CEH13734.1 - 8e-34 115.5 0.1 1.8e-33 114.4 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain EMP24_GP25L PF01105.24 CEH13735.1 - 1.9e-43 148.5 0.0 2.3e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ORC2 PF04084.14 CEH13735.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 CDC37_N PF03234.14 CEH13736.1 - 3.6e-35 121.7 4.3 6.8e-35 120.8 0.2 2.5 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_C PF08564.10 CEH13736.1 - 9.4e-20 70.6 0.3 9.4e-20 70.6 0.3 2.3 2 0 0 2 2 2 1 Cdc37 C terminal domain HTH_22 PF13309.6 CEH13736.1 - 0.051 13.7 1.0 0.4 10.8 0.1 2.4 2 0 0 2 2 2 0 HTH domain DUF1779 PF08680.10 CEH13736.1 - 0.081 13.1 3.7 0.43 10.7 0.0 2.9 3 0 0 3 3 3 0 TATA-box binding Peptidase_S30 PF01577.16 CEH13736.1 - 0.11 12.1 2.4 0.27 10.8 2.4 1.6 1 0 0 1 1 1 0 Potyvirus P1 protease DFRP_C PF16543.5 CEH13736.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.8 2 1 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 V-SNARE PF05008.15 CEH13736.1 - 3.3 8.2 7.2 1.1 9.7 0.4 3.2 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DASH_Duo1 PF08651.10 CEH13737.1 - 1.4e-18 66.4 0.0 2.1e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 Lipase_3 PF01764.25 CEH13738.1 - 1.1e-14 54.5 0.0 1.7e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CEH13738.1 - 0.18 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEH13738.1 - 0.34 11.5 5.1 0.087 13.4 1.3 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family zf-C2H2 PF00096.26 CEH13739.1 - 6.5e-09 35.8 17.7 1.1e-05 25.6 3.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 CEH13739.1 - 2.4e-07 30.8 5.5 2.4e-07 30.8 5.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_11 PF16622.5 CEH13739.1 - 1.7e-05 24.4 14.6 0.016 14.9 2.5 2.8 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 CEH13739.1 - 0.014 16.2 24.1 0.032 15.0 3.7 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger Fer4_10 PF13237.6 CEH13739.1 - 0.1 12.7 0.2 0.1 12.7 0.2 3.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain UBZ_FAAP20 PF15750.5 CEH13739.1 - 3.5 7.6 5.2 1.5 8.8 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger RRM_1 PF00076.22 CEH13740.1 - 1.7e-32 111.0 0.0 4.2e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBFB_NFYA PF02045.15 CEH13741.1 - 2.2e-09 37.8 7.4 4.4e-09 36.8 4.6 2.6 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B RSN1_7TM PF02714.15 CEH13742.1 - 1.9e-51 175.0 22.7 6.1e-36 124.1 9.0 2.6 1 1 1 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CEH13742.1 - 1.2e-37 129.1 1.3 1.2e-37 129.1 1.3 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CEH13742.1 - 2e-37 129.1 0.0 3.9e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CEH13742.1 - 1.4e-08 34.8 0.0 3.7e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter JAB PF01398.21 CEH13743.1 - 1.6e-28 99.1 0.1 2.3e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 CEH13743.1 - 9.7e-28 96.9 0.7 2.2e-27 95.8 0.7 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 CEH13743.1 - 0.00015 21.6 0.1 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CEH13743.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Nefa_Nip30_N PF10187.9 CEH13744.1 - 1.1e-28 99.6 15.9 1.1e-28 99.6 15.9 2.1 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 CEH13744.1 - 0.89 9.1 19.2 1.8 8.1 19.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) DUF4718 PF15842.5 CEH13744.1 - 2.4 7.9 5.7 2.4 7.9 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4718) SAPS PF04499.15 CEH13744.1 - 3.8 6.2 6.9 5.3 5.7 6.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HMG-CoA_red PF00368.18 CEH13745.1 - 3.2e-137 457.4 5.6 4.4e-137 457.0 5.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 CEH13745.1 - 5e-17 62.1 1.6 2.6e-07 30.6 0.2 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CEH13745.1 - 0.02 13.0 1.0 0.082 11.0 0.0 2.1 2 0 0 2 2 2 0 Patched family Zn_clus PF00172.18 CEH13747.1 - 5e-07 29.7 11.1 5e-07 29.7 11.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNase_NucA_NucB PF14040.6 CEH13748.1 - 3.3e-25 88.7 4.2 4.8e-25 88.2 4.2 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Redoxin PF08534.10 CEH13749.1 - 4.3e-27 94.6 0.0 4.8e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CEH13749.1 - 6.3e-11 42.3 0.0 7.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF4406 PF14359.6 CEH13749.1 - 0.074 13.5 0.1 8 7.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4406) DJ-1_PfpI PF01965.24 CEH13750.1 - 5.3e-42 143.4 0.2 6e-42 143.2 0.2 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 CEH13750.1 - 0.0003 20.5 0.3 0.00063 19.4 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain found in long catalases ThiJ_like PF17124.5 CEH13750.1 - 0.0017 18.0 0.2 0.035 13.8 0.0 2.2 1 1 0 2 2 2 1 ThiJ/PfpI family-like GATase_3 PF07685.14 CEH13750.1 - 0.0054 16.4 0.0 0.0077 15.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Glyco_transf_41 PF13844.6 CEH13751.1 - 2.9e-103 345.8 0.0 3.3e-49 167.6 0.0 4.0 3 1 1 4 4 4 3 Glycosyl transferase family 41 TPR_1 PF00515.28 CEH13751.1 - 1e-20 72.6 0.3 2.1e-06 27.3 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEH13751.1 - 9e-15 53.5 4.7 0.00029 20.7 0.0 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEH13751.1 - 1.4e-14 53.4 5.0 0.00028 20.5 0.0 5.5 3 2 3 6 6 6 4 TPR repeat TPR_17 PF13431.6 CEH13751.1 - 3.8e-14 51.9 9.6 0.002 18.4 0.0 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEH13751.1 - 2.5e-12 46.0 0.0 9.2e-05 22.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEH13751.1 - 1.8e-11 43.5 16.0 0.0012 18.6 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEH13751.1 - 7.3e-10 38.2 0.2 0.033 14.2 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEH13751.1 - 2.7e-09 37.2 12.6 0.032 14.5 0.1 6.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEH13751.1 - 1.5e-08 35.0 0.4 0.18 12.3 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEH13751.1 - 9.4e-07 29.2 13.8 0.022 15.6 0.0 6.5 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEH13751.1 - 0.0013 19.4 23.2 0.0012 19.4 0.0 7.0 6 1 1 7 7 6 2 Tetratricopeptide repeat BTAD PF03704.17 CEH13751.1 - 0.0017 18.8 2.4 0.069 13.6 0.0 4.1 3 1 1 4 4 4 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 CEH13751.1 - 0.01 16.0 0.0 0.099 12.8 0.0 2.8 2 1 0 2 2 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEH13751.1 - 0.041 14.5 0.0 26 5.8 0.0 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF247 PF03140.15 CEH13751.1 - 0.21 10.8 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function Rdx PF10262.9 CEH13752.1 - 1.1e-18 67.1 0.0 2.2e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 Rdx family Peroxidase_ext PF11895.8 CEH13752.1 - 0.027 14.4 3.0 0.068 13.1 3.0 1.7 1 0 0 1 1 1 0 Fungal peroxidase extension region Ribosomal_L22 PF00237.19 CEH13754.1 - 1.7e-22 79.6 1.0 2.5e-22 79.0 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DUF1351 PF07083.11 CEH13754.1 - 0.21 11.3 2.9 0.45 10.3 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) Sec8_exocyst PF04048.14 CEH13755.1 - 5e-38 130.2 0.1 1.1e-37 129.1 0.1 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 CEH13755.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 CEH13755.1 - 0.011 14.3 0.3 0.021 13.4 0.3 1.3 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 COG2 PF06148.11 CEH13755.1 - 0.35 11.0 2.3 0.35 10.9 0.4 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4795 PF16043.5 CEH13755.1 - 0.41 10.2 1.4 4.9 6.7 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) KfrA_N PF11740.8 CEH13755.1 - 7 7.4 9.2 1.9 9.2 0.3 3.5 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term Form_Nir_trans PF01226.17 CEH13758.1 - 1.4e-58 198.1 21.2 1.6e-58 197.9 21.2 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter PIG-Y PF15159.6 CEH13759.1 - 1.1e-06 29.4 0.6 1.9e-06 28.7 0.6 1.4 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PAPS_reduct PF01507.19 CEH13760.1 - 6.1e-41 140.4 0.0 8e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF2570 PF10828.8 CEH13762.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF202 PF02656.15 CEH13763.1 - 5.4e-19 68.4 0.8 5.4e-19 68.4 0.8 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF202) vATP-synt_E PF01991.18 CEH13764.1 - 1.5e-61 207.3 16.1 1.7e-61 207.1 16.1 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Afaf PF15339.6 CEH13764.1 - 0.12 12.1 5.3 0.09 12.5 2.3 1.9 2 0 0 2 2 2 0 Acrosome formation-associated factor PriA_C PF18074.1 CEH13764.1 - 1.6 9.6 10.7 2.8 8.8 1.6 2.7 3 0 0 3 3 3 0 Primosomal protein N C-terminal domain Yippee-Mis18 PF03226.14 CEH13765.1 - 2.1e-24 85.7 0.0 3.3e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly VPS13_mid_rpt PF16910.5 CEH13766.1 - 2.6e-97 324.9 6.4 3.6e-93 311.3 0.4 5.0 6 0 0 6 6 6 2 Repeating coiled region of VPS13 VPS13 PF16908.5 CEH13766.1 - 3.2e-80 269.3 2.7 2.9e-77 259.6 0.2 3.4 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 CEH13766.1 - 3.3e-79 266.1 0.0 5.5e-76 255.5 0.0 3.4 2 1 1 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 CEH13766.1 - 4.2e-66 222.1 0.6 1.7e-60 203.8 0.0 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CEH13766.1 - 4.9e-39 133.1 0.1 1.8e-38 131.2 0.1 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 CEH13766.1 - 5.5e-06 26.6 0.0 2.3e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain TRAPPC-Trs85 PF12739.7 CEH13767.1 - 5.4e-103 345.1 0.0 7.6e-103 344.6 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF572 PF04502.13 CEH13768.1 - 2.2e-05 24.3 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) Peptidase_C48 PF02902.19 CEH13769.1 - 8.9e-05 22.4 0.0 0.00099 19.0 0.0 2.0 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain CCD PF07860.11 CEH13769.1 - 0.0036 17.3 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 WisP family C-Terminal Region GATA PF00320.27 CEH13770.1 - 3.4e-12 45.8 2.5 6.6e-12 44.8 2.5 1.5 1 0 0 1 1 1 1 GATA zinc finger Sel_put PF04328.13 CEH13770.1 - 0.091 12.8 2.1 0.17 12.0 0.1 2.5 2 0 0 2 2 2 0 Selenoprotein, putative DUF768 PF05589.11 CEH13770.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF768) RasGEF PF00617.19 CEH13771.1 - 2.6e-46 158.1 0.0 4.4e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CEH13771.1 - 2.9e-06 27.5 0.0 6.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 CEH13771.1 - 0.017 14.7 0.2 0.042 13.4 0.2 1.7 1 1 0 1 1 1 0 Ras family AAA_33 PF13671.6 CEH13771.1 - 0.029 14.5 0.9 0.057 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CEH13771.1 - 0.031 14.5 0.1 0.28 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CEH13771.1 - 0.036 14.5 2.1 0.056 13.8 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 CEH13771.1 - 0.092 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 CEH13771.1 - 0.12 12.9 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Pep1_7 PF17232.2 CEH13771.1 - 4.8 7.7 0.0 4.8 7.7 0.0 4.0 4 0 0 4 4 4 0 Elicitor peptide 1-7 Pex24p PF06398.11 CEH13772.1 - 1.6e-30 106.3 3.4 1.7e-27 96.4 0.1 2.5 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Nup192 PF11894.8 CEH13773.1 - 1.2e-245 818.3 0.0 1.6e-245 817.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 ALG11_N PF15924.5 CEH13774.1 - 3.7e-74 249.3 0.0 5.2e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CEH13774.1 - 1.8e-16 60.2 0.0 3.7e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEH13774.1 - 9.9e-08 32.5 0.0 3.9e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CEH13774.1 - 0.012 15.9 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 His_Phos_2 PF00328.22 CEH13776.1 - 1.8e-28 100.0 0.0 4.4e-28 98.7 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PHD PF00628.29 CEH13777.1 - 1.6e-13 50.3 18.6 8.5e-08 32.0 6.3 3.2 3 0 0 3 3 3 2 PHD-finger TetR_C_6 PF13977.6 CEH13777.1 - 0.073 13.3 0.3 2.5 8.4 0.1 3.1 3 0 0 3 3 3 0 BetI-type transcriptional repressor, C-terminal Zf_RING PF16744.5 CEH13777.1 - 1.1 9.4 10.3 0.041 14.0 3.9 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger zf-PHD-like PF15446.6 CEH13777.1 - 1.2 8.8 9.2 0.15 11.6 3.0 2.7 4 0 0 4 4 4 0 PHD/FYVE-zinc-finger like domain FA_desaturase PF00487.24 CEH13778.1 - 1.7e-24 87.0 18.8 2.2e-24 86.7 18.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Pkinase PF00069.25 CEH13779.1 - 8.1e-52 176.2 0.0 4.5e-51 173.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH13779.1 - 1.4e-26 93.3 0.0 3.3e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase NAM-associated PF14303.6 CEH13779.1 - 2.6 8.7 11.7 7.4 7.3 11.7 1.7 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Borrelia_P83 PF05262.11 CEH13779.1 - 2.9 6.3 9.4 4.1 5.8 9.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 CEH13779.1 - 4.3 7.1 11.3 6.9 6.4 11.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP12 PF07542.11 CEH13780.1 - 1.7e-40 138.1 0.6 5.1e-40 136.5 0.0 1.9 2 0 0 2 2 2 1 ATP12 chaperone protein Nup96 PF12110.8 CEH13781.1 - 3.7e-93 311.8 1.0 5.4e-93 311.3 1.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 CEH13781.1 - 7.8e-53 178.6 0.0 1.2e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 CEH13781.1 - 6.4e-22 78.2 334.0 1.8e-07 31.9 39.5 13.5 5 2 8 13 13 13 8 Nucleoporin FG repeat region HLH PF00010.26 CEH13782.1 - 3.6e-09 36.5 0.4 9.1e-09 35.2 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Aconitase PF00330.20 CEH13783.1 - 8.6e-150 499.7 0.0 1.1e-149 499.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEH13783.1 - 1.4e-41 141.9 0.0 2.2e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Velvet PF11754.8 CEH13785.1 - 6e-48 164.0 13.3 7.7e-32 111.2 0.1 4.2 3 1 1 4 4 4 2 Velvet factor FHA PF00498.26 CEH13786.1 - 3.3e-14 53.0 0.1 6.1e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEH13786.1 - 0.00035 20.8 0.0 0.0013 19.0 0.0 1.9 2 0 0 2 2 1 1 Inner membrane component of T3SS, cytoplasmic domain Spc7 PF08317.11 CEH13786.1 - 0.0057 15.6 5.8 0.072 12.0 0.0 2.3 2 0 0 2 2 2 1 Spc7 kinetochore protein SKA2 PF16740.5 CEH13786.1 - 0.012 15.4 0.6 0.36 10.6 0.2 2.9 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 CEH13786.1 - 0.014 15.4 3.1 0.71 9.9 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 CEH13786.1 - 0.043 13.8 6.6 0.31 11.0 1.2 2.9 2 1 0 2 2 2 0 Prefoldin subunit Phage_GP20 PF06810.11 CEH13786.1 - 0.19 11.5 2.3 4.5 7.1 0.0 3.1 3 1 1 4 4 4 0 Phage minor structural protein GP20 Sugarporin_N PF11471.8 CEH13786.1 - 0.22 11.5 9.5 0.087 12.8 2.2 3.0 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension CC2-LZ PF16516.5 CEH13786.1 - 0.44 10.9 7.4 0.33 11.4 1.1 2.7 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator GED PF02212.18 CEH13786.1 - 0.58 10.4 1.8 24 5.1 0.2 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain HalX PF08663.10 CEH13786.1 - 0.59 10.5 11.3 21 5.5 0.4 4.6 2 2 3 5 5 5 0 HalX domain GAS PF13851.6 CEH13786.1 - 1.4 8.2 6.3 0.29 10.5 0.5 2.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spectrin PF00435.21 CEH13786.1 - 1.9 9.0 9.1 3.7 8.1 0.4 3.0 2 1 0 2 2 2 0 Spectrin repeat Filament PF00038.21 CEH13786.1 - 2.3 7.7 6.1 10 5.6 0.6 2.7 2 1 0 2 2 2 0 Intermediate filament protein JAKMIP_CC3 PF16034.5 CEH13786.1 - 2.7 7.9 11.2 4.9 7.0 1.5 2.7 3 0 0 3 3 2 0 JAKMIP CC3 domain Tropomyosin_1 PF12718.7 CEH13786.1 - 3.3 7.9 11.4 1.7 8.8 0.7 3.1 3 0 0 3 3 3 0 Tropomyosin like CENP-F_leu_zip PF10473.9 CEH13786.1 - 3.6 7.6 12.8 0.8 9.7 1.1 3.0 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.13 CEH13786.1 - 5.5 5.2 8.4 0.25 9.7 2.0 1.8 2 0 0 2 2 2 0 Mitotic checkpoint protein Sec2p PF06428.11 CEH13786.1 - 6.2 6.9 7.0 0.4 10.7 0.4 2.5 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p FUSC PF04632.12 CEH13786.1 - 7.9 4.9 13.7 5.8 5.3 0.1 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family GATA PF00320.27 CEH13787.1 - 5.7e-26 89.8 13.4 6.9e-14 51.2 2.8 2.4 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 CEH13787.1 - 1.6e-05 24.6 0.0 3.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 CEH13787.1 - 0.001 19.1 0.8 0.69 10.1 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 CEH13787.1 - 0.0075 16.4 3.4 0.2 11.8 0.2 2.5 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2387 PF09526.10 CEH13787.1 - 0.024 14.8 0.5 1.6 8.9 0.1 2.5 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) OrfB_Zn_ribbon PF07282.11 CEH13787.1 - 0.033 14.1 4.6 0.82 9.6 0.5 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain GET2 PF08690.10 CEH13787.1 - 0.051 13.2 3.1 0.074 12.7 2.5 1.6 1 1 0 1 1 1 0 GET complex subunit GET2 Elf1 PF05129.13 CEH13787.1 - 0.073 13.1 0.7 5.4 7.1 0.1 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like ICA69 PF04629.14 CEH13787.1 - 0.078 13.3 0.9 0.21 11.8 0.9 1.7 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain DZR PF12773.7 CEH13787.1 - 0.078 13.0 3.9 0.55 10.3 4.1 2.3 1 1 1 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 CEH13787.1 - 0.079 12.8 5.1 0.62 10.0 0.7 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 CEH13787.1 - 0.092 12.3 3.2 4.5 6.9 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Nudix_N_2 PF14803.6 CEH13787.1 - 0.18 11.8 5.9 2 8.4 1.0 2.7 2 0 0 2 2 2 0 Nudix N-terminal UCR_hinge PF02320.16 CEH13788.1 - 3.5e-23 81.6 6.1 8.4e-23 80.4 6.1 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Herpes_DNAp_acc PF04929.12 CEH13788.1 - 0.096 11.7 2.9 0.11 11.5 2.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ribosomal_L13 PF00572.18 CEH13790.1 - 1e-49 168.0 0.3 1.2e-49 167.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 AMP-binding PF00501.28 CEH13792.1 - 1.5e-66 224.8 0.0 2.1e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 CEH13792.1 - 2.1e-07 30.4 2.8 0.0018 17.9 0.0 5.1 6 1 0 6 6 6 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 CEH13792.1 - 2.7e-05 25.1 0.0 6.6e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 CEH13792.1 - 0.00024 20.8 0.5 0.00024 20.8 0.5 4.0 5 0 0 5 5 5 2 Hexapeptide repeat of succinyl-transferase PP-binding PF00550.25 CEH13792.1 - 0.00036 20.8 0.0 0.00079 19.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site BPL_N PF09825.9 CEH13794.1 - 2.2e-07 30.3 0.1 3.4e-05 23.1 0.1 2.2 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal PDEase_I PF00233.19 CEH13795.1 - 5.6e-43 147.4 0.0 1e-22 81.1 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Glycogen_syn PF05693.13 CEH13797.1 - 0 1131.7 0.0 0 1131.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 CEH13797.1 - 9.5e-07 28.8 0.1 5.3e-06 26.3 0.1 2.2 1 1 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 CEH13797.1 - 4.6e-06 26.3 0.0 0.00021 20.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEH13797.1 - 1.5e-05 25.5 0.0 0.0075 16.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CEH13797.1 - 3e-05 24.5 0.0 9.8e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 CEH13797.1 - 7e-05 22.9 0.4 0.00014 21.9 0.4 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DUF1978 PF09321.10 CEH13797.1 - 0.14 11.4 1.5 1.7 7.9 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1978) SPO22 PF08631.10 CEH13798.1 - 1.7e-19 70.4 2.4 6.4e-18 65.2 0.3 2.7 2 1 1 3 3 3 2 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.7 CEH13798.1 - 0.03 14.5 1.0 0.27 11.5 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 rve_3 PF13683.6 CEH13798.1 - 0.15 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain TPR_19 PF14559.6 CEH13798.1 - 3.1 8.4 6.3 20 5.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat 2-oxoacid_dh PF00198.23 CEH13799.1 - 3.3e-79 265.6 0.0 4.6e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CEH13799.1 - 1.4e-18 66.4 0.9 2.7e-18 65.6 0.9 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CEH13799.1 - 6.8e-05 22.6 0.1 0.0069 16.2 0.0 2.8 1 1 1 2 2 2 1 Biotin-lipoyl like Coilin_N PF15862.5 CEH13799.1 - 0.00015 21.6 9.3 0.00043 20.1 9.3 1.8 1 1 0 1 1 1 1 Coilin N-terminus HlyD_3 PF13437.6 CEH13799.1 - 0.0002 22.0 0.2 0.044 14.5 0.0 2.5 1 1 1 2 2 2 1 HlyD family secretion protein Presenilin PF01080.17 CEH13799.1 - 0.0021 16.9 13.6 0.0035 16.2 13.6 1.3 1 0 0 1 1 1 1 Presenilin TFIIF_alpha PF05793.12 CEH13799.1 - 0.0027 16.4 26.9 0.0034 16.0 26.9 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GCV_H PF01597.19 CEH13799.1 - 0.005 16.7 0.5 0.012 15.5 0.5 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein DDHD PF02862.17 CEH13799.1 - 0.023 14.8 5.6 0.039 14.1 5.6 1.4 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 CEH13799.1 - 0.036 12.4 19.9 0.047 12.0 19.9 1.1 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 CEH13799.1 - 0.13 12.5 11.9 0.2 11.9 11.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SpoIIP PF07454.11 CEH13799.1 - 0.14 11.6 13.1 0.21 11.0 13.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Neur_chan_memb PF02932.16 CEH13799.1 - 0.27 11.3 6.2 0.38 10.8 6.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CCSAP PF15748.5 CEH13799.1 - 0.27 11.4 19.6 0.4 10.8 19.6 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Paf1 PF03985.13 CEH13799.1 - 0.51 9.3 22.7 0.79 8.7 22.7 1.3 1 0 0 1 1 1 0 Paf1 NPR3 PF03666.13 CEH13799.1 - 0.59 8.9 17.8 0.83 8.4 17.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.10 CEH13799.1 - 0.77 10.1 21.6 1.6 9.0 21.6 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GREB1 PF15782.5 CEH13799.1 - 0.83 6.7 12.5 0.99 6.4 12.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CEH13799.1 - 1.2 8.3 8.4 1.6 7.8 8.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Band_3_cyto PF07565.13 CEH13799.1 - 1.2 8.9 7.9 2.3 7.9 7.9 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Borrelia_P83 PF05262.11 CEH13799.1 - 1.6 7.1 18.6 2.2 6.7 18.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Nop14 PF04147.12 CEH13799.1 - 1.7 6.8 25.5 2.2 6.4 25.5 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 CEH13799.1 - 3 7.6 23.7 5.2 6.8 23.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 CEH13799.1 - 3.2 7.2 14.5 5 6.6 14.5 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF913 PF06025.12 CEH13799.1 - 3.6 6.5 9.2 5.1 6.0 9.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) LAP1C PF05609.12 CEH13799.1 - 3.7 6.5 17.4 5.1 6.1 17.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) FAM60A PF15396.6 CEH13799.1 - 4 7.4 13.0 7 6.6 13.0 1.4 1 0 0 1 1 1 0 Protein Family FAM60A PTPRCAP PF15713.5 CEH13799.1 - 4.2 7.7 24.7 7.6 6.8 24.7 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated MDM10 PF12519.8 CEH13799.1 - 6.2 5.6 11.6 8.4 5.1 11.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Spt20 PF12090.8 CEH13799.1 - 6.4 6.3 24.8 10 5.7 24.8 1.2 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CEH13799.1 - 7.5 5.5 16.0 12 4.9 16.0 1.4 1 0 0 1 1 1 0 Drosophila roughex protein SAPS PF04499.15 CEH13799.1 - 9.5 4.9 17.4 3.9 6.1 14.3 1.7 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein FAM76 PF16046.5 CEH13799.1 - 9.9 5.4 22.8 16 4.7 21.2 1.9 2 0 0 2 2 2 0 FAM76 protein MARVEL PF01284.23 CEH13800.1 - 0.0032 17.5 13.3 0.0032 17.5 13.3 1.7 1 1 1 2 2 2 1 Membrane-associating domain DUF3130 PF11328.8 CEH13804.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 Scaffolding_pro PF11418.8 CEH13804.1 - 0.11 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Phi29 scaffolding protein CusF_Ec PF11604.8 CEH13805.1 - 0.066 13.2 0.0 6.4 6.8 0.0 2.9 3 0 0 3 3 3 0 Copper binding periplasmic protein CusF PPR_2 PF13041.6 CEH13806.1 - 1.5e-14 53.9 0.1 0.014 15.6 0.0 7.2 6 2 2 8 8 8 4 PPR repeat family PPR PF01535.20 CEH13806.1 - 8.8e-14 50.7 2.3 0.00011 22.2 0.0 6.4 5 1 0 5 5 5 3 PPR repeat PPR_1 PF12854.7 CEH13806.1 - 5e-11 42.1 6.5 9e-05 22.1 0.0 6.1 6 1 0 6 6 6 3 PPR repeat PPR_3 PF13812.6 CEH13806.1 - 4.9e-09 36.1 0.0 0.1 12.7 0.0 3.8 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR_long PF17177.4 CEH13806.1 - 9.1e-07 28.4 2.2 0.013 14.9 0.1 4.3 4 1 0 5 5 5 2 Pentacotripeptide-repeat region of PRORP Sec34 PF04136.15 CEH13807.1 - 4.7e-31 107.7 0.0 1.1e-30 106.5 0.0 1.6 1 0 0 1 1 1 1 Sec34-like family Exo70 PF03081.15 CEH13807.1 - 0.099 11.7 0.5 5.6 5.9 0.0 2.5 2 0 0 2 2 2 0 Exo70 exocyst complex subunit DEAD PF00270.29 CEH13808.1 - 3.2e-35 121.5 0.0 7.3e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH13808.1 - 4.5e-21 75.3 0.0 1.2e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH13808.1 - 5.3e-09 36.3 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CEH13808.1 - 7.7e-05 23.1 0.9 0.0037 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CEH13808.1 - 0.0061 16.8 1.1 0.25 11.6 1.1 2.6 1 1 0 1 1 1 1 AAA domain RAP1 PF07218.11 CEH13808.1 - 4.6 5.4 11.5 7 4.8 11.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ubiquitin PF00240.23 CEH13809.1 - 1.9e-34 117.2 0.5 3.3e-34 116.5 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 CEH13809.1 - 2.2e-24 85.3 0.8 2.2e-24 85.3 0.8 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CEH13809.1 - 4.3e-16 58.5 0.6 7.6e-16 57.7 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEH13809.1 - 3.1e-05 24.3 0.1 0.00014 22.3 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEH13809.1 - 4.2e-05 23.6 0.5 0.00097 19.2 0.6 2.4 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CEH13809.1 - 0.0063 16.8 0.6 0.012 15.9 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 CEH13809.1 - 0.0064 17.0 0.5 0.0089 16.6 0.5 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 CEH13809.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 CEH13809.1 - 0.018 15.1 1.1 5.7 7.1 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 CEH13809.1 - 0.051 13.8 0.4 0.085 13.1 0.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain W2 PF02020.18 CEH13810.1 - 0.014 15.6 0.2 0.029 14.5 0.2 1.6 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Metallophos PF00149.28 CEH13811.1 - 2.7e-23 83.5 0.0 4.9e-21 76.2 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEH13811.1 - 0.0039 17.6 0.3 0.0078 16.6 0.3 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain aGPT-Pplase1 PF18723.1 CEH13813.1 - 1.9e-73 247.3 0.0 2.6e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 CEH13813.1 - 7.7e-09 35.3 0.3 1.8e-08 34.1 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DASH_Dad4 PF08650.10 CEH13814.1 - 1.6e-27 95.3 1.6 1.8e-27 95.1 1.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 CEH13814.1 - 0.038 14.2 1.0 0.048 13.8 1.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 tRNA-synt_2b PF00587.25 CEH13815.1 - 6.4e-36 124.0 0.0 1.1e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CEH13815.1 - 5.9e-15 55.4 4.2 1.1e-14 54.5 4.2 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 CEH13815.1 - 0.077 13.1 1.1 0.2 11.7 1.1 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 CEH13817.1 - 0.0036 16.2 11.6 0.0036 16.2 11.6 7.1 1 1 5 7 7 7 5 Spc7 kinetochore protein GWT1 PF06423.12 CEH13819.1 - 2e-25 89.6 0.0 4.1e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 GWT1 Ligase_CoA PF00549.19 CEH13820.1 - 6.3e-12 45.6 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 CEH13820.1 - 5.9e-07 30.1 0.4 1.5e-06 28.8 0.4 1.7 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 CEH13820.1 - 2.9e-06 27.1 0.0 9.4e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain MFS_1 PF07690.16 CEH13823.1 - 4.7e-37 127.7 41.1 4.7e-37 127.7 41.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH13823.1 - 2.7e-13 49.6 13.1 2.7e-13 49.6 13.1 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CEH13823.1 - 5.4e-06 25.1 6.4 9.5e-06 24.3 6.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HemY_N PF07219.13 CEH13823.1 - 0.082 13.1 0.1 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 HemY protein N-terminus MFS_1_like PF12832.7 CEH13823.1 - 0.37 9.6 11.6 0.16 10.8 8.4 2.1 2 0 0 2 2 2 0 MFS_1 like family Arc PF03869.14 CEH13824.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Arc-like DNA binding domain IKI3 PF04762.12 CEH13826.1 - 9.3e-191 636.2 0.0 1.9e-147 492.9 0.0 2.5 1 1 1 2 2 2 2 IKI3 family DUF29 PF01724.16 CEH13826.1 - 0.73 10.1 3.7 4.4 7.5 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF29 PP2C_2 PF13672.6 CEH13827.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C tRNA-synt_2 PF00152.20 CEH13828.1 - 2.2e-78 263.5 0.0 3.3e-78 262.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 CEH13828.1 - 0.03 14.3 0.1 0.58 10.1 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 CEH13828.1 - 0.037 13.5 0.0 0.97 8.9 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) EHN PF06441.12 CEH13829.1 - 3.1e-26 91.9 4.7 1.6e-20 73.5 0.3 2.5 1 1 1 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CEH13829.1 - 1.1e-11 44.9 0.5 1.7e-11 44.2 0.5 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_KA1 PF16797.5 CEH13829.1 - 0.079 12.7 1.0 7.7 6.2 0.1 2.4 1 1 1 2 2 2 0 Fungal kinase associated-1 domain RNA_lig_T4_1 PF09511.10 CEH13830.1 - 3.1e-70 236.5 0.1 1.4e-69 234.4 0.0 2.0 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.11 CEH13830.1 - 3.4e-22 79.3 0.3 3.3e-08 33.8 0.2 3.5 2 1 1 3 3 3 3 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 CEH13830.1 - 6.6e-17 61.8 0.1 2.2e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain KTI12 PF08433.10 CEH13830.1 - 0.021 14.3 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 2_5_RNA_ligase2 PF13563.6 CEH13830.1 - 0.028 14.3 2.6 4.6 7.1 0.1 2.9 3 0 0 3 3 3 0 2'-5' RNA ligase superfamily CPT PF07931.12 CEH13830.1 - 0.037 13.9 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein HSP20 PF00011.21 CEH13831.1 - 1e-20 73.8 0.4 1.7e-19 69.9 0.4 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CEH13831.1 - 3.3e-07 29.7 0.0 6.9e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF150_C PF17384.2 CEH13831.1 - 0.073 13.2 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 RimP C-terminal SH3 domain LTV PF04180.14 CEH13832.1 - 4.5e-69 234.0 37.4 4.3e-50 171.5 3.6 4.4 2 1 2 4 4 4 4 Low temperature viability protein HAP1_N PF04849.13 CEH13833.1 - 7.1e-06 25.4 9.7 8.4e-06 25.2 1.0 3.1 3 0 0 3 3 3 1 HAP1 N-terminal conserved region ATP-synt_D PF01813.17 CEH13833.1 - 0.2 11.5 1.4 0.33 10.7 0.4 1.8 2 0 0 2 2 2 0 ATP synthase subunit D Filament PF00038.21 CEH13833.1 - 0.35 10.4 7.7 0.14 11.8 3.7 2.1 2 0 0 2 2 2 0 Intermediate filament protein HAUS-augmin3 PF14932.6 CEH13833.1 - 0.4 10.2 3.4 11 5.5 3.4 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 ABC_tran_CTD PF16326.5 CEH13833.1 - 0.43 10.9 11.5 0.69 10.2 4.3 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain TPR_MLP1_2 PF07926.12 CEH13833.1 - 0.46 10.5 11.6 0.46 10.6 8.4 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlxA PF14282.6 CEH13833.1 - 0.6 10.1 5.4 2.2 8.4 5.4 2.0 1 0 0 1 1 1 0 FlxA-like protein DUF3450 PF11932.8 CEH13833.1 - 0.78 9.0 7.7 2.5 7.3 7.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) SHE3 PF17078.5 CEH13833.1 - 1.4 8.5 4.5 1.2 8.8 3.0 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 CEH13833.1 - 3.4 8.2 10.8 0.65 10.5 3.2 2.9 2 0 0 2 2 2 0 Apg6 coiled-coil region RRM_1 PF00076.22 CEH13834.1 - 6.3e-30 102.8 2.5 6.9e-18 64.2 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCV_T_C PF08669.11 CEH13834.1 - 0.091 12.7 0.2 0.59 10.1 0.1 2.2 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain zf-LYAR PF08790.11 CEH13836.1 - 1.4e-12 47.3 0.4 2.6e-12 46.4 0.4 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger G-patch PF01585.23 CEH13836.1 - 3.9e-06 26.6 2.8 1.2e-05 25.1 2.8 1.8 1 0 0 1 1 1 1 G-patch domain TFIIA PF03153.13 CEH13836.1 - 2.8 7.9 37.4 2.1 8.2 6.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GDP_Man_Dehyd PF16363.5 CEH13837.1 - 1.2e-43 149.8 0.0 1.6e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEH13837.1 - 2.5e-39 135.2 0.0 3.3e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEH13837.1 - 1e-13 50.9 0.0 5.1e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CEH13837.1 - 1.2e-08 34.4 0.0 9e-08 31.6 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CEH13837.1 - 3.5e-08 32.9 0.3 7.1e-08 31.9 0.3 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CEH13837.1 - 8e-06 25.9 0.5 3e-05 24.0 0.5 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CEH13837.1 - 5.4e-05 22.5 0.0 0.00012 21.4 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CEH13837.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 CEH13837.1 - 0.096 12.2 0.2 0.76 9.3 0.2 2.3 1 1 0 1 1 1 0 NmrA-like family Acetyltransf_1 PF00583.25 CEH13838.1 - 4.7e-10 39.7 0.0 6.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEH13838.1 - 4.9e-10 39.4 0.1 7.3e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEH13838.1 - 7.4e-08 32.7 0.0 1.4e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEH13838.1 - 1.5e-07 31.2 0.0 2.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CEH13838.1 - 0.0064 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Autophagy_act_C PF03987.15 CEH13839.1 - 2.1e-11 44.3 0.0 5.3e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain NMT1 PF09084.11 CEH13839.1 - 0.00073 19.5 0.1 0.0012 18.8 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like CRM1_C PF08767.11 CEH13840.1 - 1.4e-117 392.4 1.8 9.8e-117 389.7 0.0 2.8 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 CEH13840.1 - 1.4e-38 132.3 5.2 1.4e-38 132.3 5.2 3.3 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CEH13840.1 - 1.2e-33 114.5 4.1 1.2e-33 114.5 4.1 2.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CEH13840.1 - 4.7e-30 103.4 3.4 5.7e-30 103.2 0.9 2.7 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CEH13840.1 - 1.8e-19 69.0 1.1 4.9e-19 67.6 1.1 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CEH13840.1 - 8.1e-14 51.3 1.5 3.8e-13 49.1 1.5 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain UCH PF00443.29 CEH13840.1 - 0.16 11.4 0.0 0.4 10.1 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF4795 PF16043.5 CEH13840.1 - 1.3 8.5 4.3 0.61 9.7 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Ank_2 PF12796.7 CEH13842.1 - 2.9e-51 172.0 0.4 1e-13 51.6 0.0 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEH13842.1 - 1.2e-30 105.4 0.6 1.2e-08 35.3 0.0 5.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.19 CEH13842.1 - 1.6e-26 94.2 10.9 7e-17 62.4 0.8 3.4 2 1 0 3 3 3 2 SPX domain Ank_3 PF13606.6 CEH13842.1 - 3.7e-19 66.8 0.5 0.0073 16.7 0.0 7.8 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 CEH13842.1 - 5e-19 67.8 5.3 0.0035 17.7 0.0 7.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 CEH13842.1 - 5.1e-18 64.9 3.3 0.0029 17.9 0.0 7.0 1 1 6 7 7 7 7 Ankyrin repeats (many copies) GDPD PF03009.17 CEH13842.1 - 5.7e-11 42.6 0.0 1.7e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RFX_DNA_binding PF02257.15 CEH13843.1 - 8.7e-14 51.9 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain Fis1_TPR_N PF14852.6 CEH13846.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat V-SNARE PF05008.15 CEH13851.1 - 5.6e-17 61.9 2.9 5.6e-17 61.9 2.9 2.5 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 CEH13851.1 - 1.1e-15 57.7 7.7 1.1e-15 57.7 7.7 3.3 4 1 1 5 5 5 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 CEH13851.1 - 0.00027 19.1 0.7 0.00049 18.2 0.7 1.4 1 1 0 1 1 1 1 Prominin Sec20 PF03908.13 CEH13851.1 - 0.0012 18.7 0.3 0.0028 17.5 0.3 1.7 1 0 0 1 1 1 1 Sec20 SNARE PF05739.19 CEH13851.1 - 0.041 13.9 0.8 0.13 12.3 0.8 1.9 1 0 0 1 1 1 0 SNARE domain DUF3510 PF12022.8 CEH13851.1 - 0.076 13.4 0.3 0.076 13.4 0.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) Sec8_exocyst PF04048.14 CEH13851.1 - 0.079 12.8 3.9 0.9 9.4 0.5 2.5 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain LXG PF04740.12 CEH13851.1 - 0.11 12.2 3.7 0.17 11.6 0.4 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily FAM92 PF06730.11 CEH13851.1 - 0.13 11.7 2.6 0.095 12.1 0.5 1.7 2 0 0 2 2 2 0 FAM92 protein BAR PF03114.18 CEH13851.1 - 0.13 11.9 2.7 0.49 10.0 2.7 2.0 1 1 0 1 1 1 0 BAR domain zf-CpG_bind_C PF12269.8 CEH13851.1 - 0.67 9.7 4.4 0.6 9.8 0.4 2.0 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain YqjK PF13997.6 CEH13851.1 - 0.68 10.2 9.1 0.27 11.5 1.8 2.5 2 0 0 2 2 2 0 YqjK-like protein DUF3847 PF12958.7 CEH13851.1 - 0.76 9.9 7.9 9.4 6.4 0.7 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3847) DUF3813 PF12758.7 CEH13851.1 - 0.77 10.1 6.4 3.4 8.1 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Exonuc_VII_L PF02601.15 CEH13851.1 - 1.9 8.0 12.5 34 3.9 12.5 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit WXG100 PF06013.12 CEH13851.1 - 2.1 8.6 14.4 1.4 9.2 1.3 4.7 3 1 1 5 5 5 0 Proteins of 100 residues with WXG DUF2730 PF10805.8 CEH13851.1 - 2.6 8.2 7.9 0.83 9.8 0.2 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) DUF4407 PF14362.6 CEH13851.1 - 4.2 6.6 14.9 24 4.1 14.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RNA_pol_Rpb1_5 PF04998.17 CEH13852.1 - 7e-83 278.1 0.0 2.3e-82 276.4 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CEH13852.1 - 1.7e-63 213.8 0.0 3.4e-63 212.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CEH13852.1 - 4.7e-36 124.1 0.0 8.5e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CEH13852.1 - 1.2e-25 90.5 0.0 2.1e-21 76.6 0.0 3.6 4 0 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 CEH13852.1 - 3.9e-22 78.2 0.0 1.1e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Cwf_Cwc_15 PF04889.12 CEH13852.1 - 1.8 8.3 17.3 4.6 6.9 17.3 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol3_a_NII PF11490.8 CEH13852.1 - 4 7.3 4.7 10 6.1 4.7 1.7 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Ceramidase PF05875.12 CEH13853.1 - 3.9e-77 259.2 1.6 4.6e-77 259.0 1.6 1.0 1 0 0 1 1 1 1 Ceramidase QWRF PF04484.12 CEH13853.1 - 6.4 6.4 10.5 9.5 5.9 10.5 1.1 1 0 0 1 1 1 0 QWRF family DnaJ-X PF14308.6 CEH13854.1 - 1.2e-64 217.7 0.9 1.2e-64 217.7 0.9 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CEH13854.1 - 4.2e-20 71.6 0.2 1.2e-19 70.2 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain FSA_C PF10479.9 CEH13854.1 - 0.044 11.9 2.1 0.062 11.4 2.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ndc1_Nup PF09531.10 CEH13854.1 - 1.5 7.4 2.5 2.2 6.8 2.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ank_2 PF12796.7 CEH13855.1 - 8e-09 36.0 0.1 7.3e-07 29.7 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEH13855.1 - 2.1e-08 34.5 2.6 7.3e-06 26.4 0.5 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CEH13855.1 - 5.4e-08 32.9 0.0 0.0057 17.0 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CEH13855.1 - 6.6e-07 29.2 0.0 0.022 15.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CEH13855.1 - 0.006 16.9 0.8 0.069 13.5 0.5 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Sds3 PF08598.11 CEH13856.1 - 3e-28 99.3 4.9 6.1e-28 98.3 4.9 1.5 1 0 0 1 1 1 1 Sds3-like Spindle_Spc25 PF08234.12 CEH13858.1 - 3.8e-12 46.2 0.0 1.2e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Exonuc_VII_L PF02601.15 CEH13858.1 - 0.047 13.2 3.1 0.057 13.0 3.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 CEH13858.1 - 0.7 8.7 16.6 0.3 9.9 13.5 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein TMCO5 PF14992.6 CEH13858.1 - 1.5 8.3 15.0 2.2 7.8 15.0 1.2 1 0 0 1 1 1 0 TMCO5 family Atg14 PF10186.9 CEH13858.1 - 3 6.8 10.5 4.7 6.2 10.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 CEH13858.1 - 6.9 7.0 12.3 0.72 10.1 6.2 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Ribonuc_red_sm PF00268.21 CEH13859.1 - 8.4e-120 399.4 1.8 1.1e-119 399.1 1.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SPC12 PF06645.13 CEH13860.1 - 7.8e-27 93.2 0.4 9.7e-27 92.9 0.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ExoD PF06055.12 CEH13860.1 - 0.07 12.5 1.4 0.24 10.8 1.1 1.8 1 1 1 2 2 2 0 Exopolysaccharide synthesis, ExoD O-antigen_lig PF13425.6 CEH13860.1 - 0.11 11.3 1.8 0.13 11.0 1.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein NmrA PF05368.13 CEH13861.1 - 3.5e-32 111.8 0.2 4.8e-32 111.4 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CEH13861.1 - 1.8e-08 34.5 0.0 2.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Mito_carr PF00153.27 CEH13862.1 - 5.4e-57 189.7 11.0 7.2e-23 80.3 0.0 5.0 3 1 0 3 3 3 3 Mitochondrial carrier protein RIX1 PF08167.12 CEH13864.1 - 2.5e-07 30.6 0.3 2.5e-07 30.6 0.3 3.0 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Brix PF04427.18 CEH13866.1 - 3.8e-26 92.4 0.1 4.9e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 Brix domain EAP30 PF04157.16 CEH13867.1 - 1.5e-20 73.5 0.0 6.9e-20 71.3 0.0 2.0 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 CEH13867.1 - 3.6e-09 36.7 0.0 9.6e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 CEH13867.1 - 1.5e-05 24.2 15.1 0.0027 17.1 4.0 3.7 2 2 0 2 2 2 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 CEH13867.1 - 0.0023 17.2 7.7 0.09 12.1 0.3 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 CEH13867.1 - 0.23 11.5 5.7 0.37 10.9 0.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 CEH13867.1 - 2.7 8.1 11.4 1.8 8.7 0.2 2.9 2 2 1 3 3 3 0 Sec23/Sec24 zinc finger Rad21_Rec8_N PF04825.13 CEH13868.1 - 1.1e-35 122.1 0.0 1.7e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CEH13868.1 - 1.1e-14 53.4 0.0 2.6e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 CEH13868.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Ribosomal_S5 PF00333.20 CEH13869.1 - 5e-17 61.6 0.9 9.8e-17 60.7 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CEH13869.1 - 1.7e-15 56.2 0.0 4.3e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain ParA PF10609.9 CEH13870.1 - 3.7e-57 193.6 0.0 6.9e-46 156.7 0.0 2.0 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase PcrB PF01884.17 CEH13870.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 PcrB family AAA_26 PF13500.6 CEH13870.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain Spt5-NGN PF03439.13 CEH13870.1 - 0.22 11.5 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Polyketide_cyc PF03364.20 CEH13871.1 - 5e-24 85.0 0.0 6.3e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 CEH13871.1 - 3.8e-08 33.7 0.0 5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_15 PF09445.10 CEH13872.1 - 1.6e-13 50.5 0.0 5.5e-12 45.6 0.0 2.2 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase LapA_dom PF06305.11 CEH13873.1 - 0.065 13.1 0.8 0.2 11.5 0.2 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Glyco_hydro_88 PF07470.13 CEH13876.1 - 9.8e-13 47.9 0.2 1.5e-12 47.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 HILPDA PF15220.6 CEH13876.1 - 0.068 13.3 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated Methyltransf_12 PF08242.12 CEH13877.1 - 1e-09 39.0 0.2 7.7e-09 36.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH13877.1 - 1.5e-09 38.0 0.0 3.2e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH13877.1 - 1.2e-07 32.3 0.0 3e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH13877.1 - 0.001 18.9 0.0 0.016 15.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CEH13877.1 - 0.0037 16.8 0.1 0.0072 15.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CEH13877.1 - 0.0042 17.7 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Gastrin PF00918.17 CEH13877.1 - 0.21 12.6 0.3 0.21 12.6 0.3 1.6 2 0 0 2 2 2 0 Gastrin/cholecystokinin family DUF3281 PF11685.8 CEH13878.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3281) DPM2 PF07297.12 CEH13879.1 - 9.3e-28 96.4 0.3 1.1e-27 96.2 0.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 CEH13879.1 - 3.4e-05 23.7 0.5 4e-05 23.5 0.5 1.1 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 CEH13879.1 - 0.0011 19.0 0.5 0.0013 18.7 0.5 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III PsbW PF07123.12 CEH13879.1 - 0.25 11.4 0.7 0.39 10.7 0.7 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) TPP_enzyme_N PF02776.18 CEH13880.1 - 9.2e-54 181.6 0.0 2.2e-53 180.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CEH13880.1 - 5.7e-45 152.8 0.0 1.6e-43 148.1 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CEH13880.1 - 4.1e-43 146.4 1.1 2.1e-42 144.1 0.2 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 CEH13880.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Tubulin PF00091.25 CEH13881.1 - 4e-66 223.0 0.0 5.4e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEH13881.1 - 1.6e-48 164.0 0.0 2.4e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CEH13881.1 - 0.00025 20.8 0.0 0.00065 19.4 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CEH13881.1 - 0.071 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin like SAP18 PF06487.12 CEH13883.1 - 8.4e-23 81.1 0.0 1.8e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Vps16_N PF04841.13 CEH13884.1 - 1.9e-73 247.6 0.0 1.3e-49 169.1 0.0 2.4 3 0 0 3 3 3 2 Vps16, N-terminal region Vps16_C PF04840.12 CEH13884.1 - 5.9e-60 203.0 0.2 8.2e-33 113.8 0.1 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 CEH13884.1 - 0.087 13.1 0.0 14 6.0 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 CEH13885.1 - 1.2e-37 129.3 0.0 3.2e-36 124.7 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH13885.1 - 4.2e-18 65.7 0.0 1.2e-17 64.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CEH13885.1 - 2.2e-15 56.6 0.3 2.2e-15 56.6 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CEH13885.1 - 0.00029 20.9 0.0 0.0008 19.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEH13885.1 - 0.014 15.7 2.2 0.95 9.7 0.3 3.4 2 1 0 2 2 2 0 AAA domain Trimer_CC PF08954.11 CEH13885.1 - 0.022 14.3 0.0 0.093 12.3 0.0 2.1 1 0 0 1 1 1 0 Trimerisation motif Prosystemin PF07376.11 CEH13885.1 - 0.31 10.5 3.0 0.55 9.7 3.0 1.2 1 0 0 1 1 1 0 Prosystemin HVSL PF09749.9 CEH13886.1 - 1.9e-20 73.4 0.0 2.6e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 CEH13886.1 - 0.0014 18.5 0.4 0.0037 17.2 0.1 1.8 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily RNA_pol_L_2 PF13656.6 CEH13887.1 - 9.1e-27 92.7 0.0 1.2e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CEH13887.1 - 4.8e-12 45.1 0.0 7.9e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L7Ae PF01248.26 CEH13888.1 - 1.9e-18 66.0 0.3 3.8e-18 65.0 0.2 1.6 1 1 1 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CEH13888.1 - 0.022 14.8 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 SUI1 PF01253.22 CEH13889.1 - 6.9e-28 97.0 0.4 1e-27 96.5 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 PPTA PF01239.22 CEH13890.1 - 9.8e-33 110.9 18.0 2e-09 36.9 0.2 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF3449 PF11931.8 CEH13892.1 - 3.3e-71 238.9 1.6 1.1e-70 237.1 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 CEH13892.1 - 5.1e-21 75.0 0.0 1.1e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 CEH13892.1 - 6.2e-11 42.3 1.2 1.3e-06 28.5 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEH13892.1 - 1.4e-09 38.0 1.9 1.9e-06 28.0 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 CEH13892.1 - 7.8e-07 28.9 0.6 7.8e-07 28.9 0.6 2.1 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-DBF PF07535.12 CEH13892.1 - 0.0005 20.1 1.0 0.039 14.1 0.0 2.6 2 0 0 2 2 2 1 DBF zinc finger zf-C2H2_2 PF12756.7 CEH13892.1 - 0.068 13.5 0.1 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CEH13892.1 - 0.15 13.0 1.5 24 6.1 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger RRN3 PF05327.11 CEH13893.1 - 3.6e-152 507.8 0.0 7.1e-152 506.8 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Ribonuclease_3 PF00636.26 CEH13895.1 - 2e-05 25.2 0.0 8.5e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain Chon_Sulph_att PF06566.11 CEH13895.1 - 2.4 8.0 7.3 12 5.6 7.3 2.0 1 1 0 1 1 1 0 Chondroitin sulphate attachment domain HicB_lk_antitox PF15919.5 CEH13896.1 - 0.059 13.5 0.0 0.063 13.4 0.0 1.0 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system ATP-synt_J PF04911.12 CEH13898.1 - 1.7e-22 78.7 0.3 1.9e-22 78.6 0.3 1.0 1 0 0 1 1 1 1 ATP synthase j chain ResIII PF04851.15 CEH13899.1 - 3.5e-19 69.5 0.0 7.5e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEH13899.1 - 2.9e-18 66.2 0.3 8.1e-18 64.8 0.3 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEH13899.1 - 4.3e-15 55.9 0.0 1.5e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CEH13899.1 - 0.00018 21.2 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Cupin_2 PF07883.11 CEH13900.1 - 7.7e-10 38.4 0.1 1.6e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 Cupin domain Lyx_isomer PF07385.12 CEH13900.1 - 0.038 13.2 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 D-lyxose isomerase AraC_binding PF02311.19 CEH13900.1 - 0.098 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Chs7 PF12271.8 CEH13901.1 - 3.7e-116 387.5 19.7 4.2e-116 387.3 19.7 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone NMT1 PF09084.11 CEH13903.1 - 7.5e-66 222.2 0.0 9.6e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 CEH13903.1 - 7.7e-06 25.8 0.3 7.8e-05 22.5 0.1 2.3 2 1 0 2 2 2 1 NMT1-like family Phosphonate-bd PF12974.7 CEH13903.1 - 0.0063 16.1 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.7 CEH13903.1 - 0.0064 15.6 0.0 0.052 12.7 0.0 2.0 1 1 1 2 2 2 1 PBP superfamily domain Tfb2 PF03849.14 CEH13904.1 - 2.9e-116 388.3 0.0 3.4e-116 388.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CEH13904.1 - 3.2e-25 88.3 0.1 7e-25 87.2 0.1 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CEH13904.1 - 0.016 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain FluMu_N PF17891.1 CEH13904.1 - 0.22 11.3 1.4 21 5.0 0.0 2.7 3 0 0 3 3 3 0 Mu-like prophage FluMu N-terminal domain Ribosomal_S7e PF01251.18 CEH13905.1 - 9.8e-51 172.1 6.3 8.2e-27 94.1 0.2 2.5 2 1 1 3 3 3 2 Ribosomal protein S7e RNA_pol_Rpb2_6 PF00562.28 CEH13906.1 - 2.6e-109 365.9 0.0 5.3e-109 364.9 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CEH13906.1 - 1.3e-34 119.5 0.0 5.3e-34 117.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CEH13906.1 - 4.9e-29 100.3 0.1 2.4e-26 91.7 0.0 2.8 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CEH13906.1 - 4.6e-24 84.2 0.0 9.4e-24 83.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 CEH13906.1 - 7.9e-18 64.8 0.0 5.3e-17 62.1 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CEH13906.1 - 1.8e-15 57.1 0.0 2.8e-14 53.3 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 ESCRT-II PF05871.12 CEH13907.1 - 4.1e-30 104.9 0.1 8.1e-30 103.9 0.1 1.5 1 0 0 1 1 1 1 ESCRT-II complex subunit UBA PF00627.31 CEH13907.1 - 2.2e-07 30.7 0.0 0.043 13.7 0.0 2.8 3 0 0 3 3 3 2 UBA/TS-N domain Vta1 PF04652.16 CEH13908.1 - 1.1e-12 48.2 0.3 3e-11 43.5 0.1 2.2 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 CEH13908.1 - 6.4e-12 45.0 2.4 1.5e-11 43.8 2.4 1.7 1 0 0 1 1 1 1 Vta1 C-terminal domain Abhydrolase_1 PF00561.20 CEH13910.1 - 3.9e-10 39.8 0.1 9e-10 38.6 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH13910.1 - 0.00078 18.8 0.3 0.12 11.6 0.1 3.0 3 1 0 3 3 3 2 Serine aminopeptidase, S33 Cpn60_TCP1 PF00118.24 CEH13911.1 - 2.1e-144 481.8 14.6 8.4e-90 301.7 6.0 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Bim_N PF06773.11 CEH13912.1 - 0.1 12.3 0.4 3.9 7.2 0.1 2.4 2 0 0 2 2 2 0 Bim protein N-terminus RrnaAD PF00398.20 CEH13913.1 - 1.4e-56 191.5 0.0 1.9e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CEH13913.1 - 7e-07 29.9 0.0 2.9e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH13913.1 - 2.4e-05 24.9 0.0 9.1e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 CEH13913.1 - 0.0018 17.9 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 CEH13913.1 - 0.039 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CEH13913.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 CEH13913.1 - 0.068 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CEH13913.1 - 0.069 13.9 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CEH13913.1 - 0.079 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_28 PF02636.17 CEH13913.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 CEH13913.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.13 CEH13913.1 - 0.19 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.15 CEH13914.1 - 2.8e-46 158.1 0.2 1.4e-23 83.9 0.5 3.0 2 1 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CEH13914.1 - 0.14 12.8 0.0 1.1 10.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 CEH13914.1 - 0.15 11.6 0.0 15 5.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain WD40 PF00400.32 CEH13915.1 - 9.5e-34 114.9 26.4 3.8e-09 37.0 0.1 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CEH13915.1 - 6.6e-27 94.3 0.0 1.1e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CEH13915.1 - 3.2e-06 27.3 0.0 0.04 14.2 0.0 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEH13915.1 - 0.00065 18.5 0.5 0.22 10.1 0.0 3.3 4 0 0 4 4 4 2 Nucleoporin Nup120/160 MAP65_ASE1 PF03999.12 CEH13915.1 - 0.35 9.5 2.1 0.51 9.0 2.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TAP42 PF04177.12 CEH13916.1 - 1.7e-59 201.6 0.0 2.9e-59 200.8 0.0 1.4 1 1 0 1 1 1 1 TAP42-like family PCI PF01399.27 CEH13917.1 - 4.5e-12 46.4 0.1 1e-11 45.3 0.1 1.6 1 0 0 1 1 1 1 PCI domain ubiquitin PF00240.23 CEH13918.1 - 4.5e-137 446.0 18.7 1.3e-33 114.6 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 CEH13918.1 - 2.8e-63 209.7 20.7 3e-15 55.8 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEH13918.1 - 3.5e-23 81.8 9.2 0.00045 20.6 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 CEH13918.1 - 4e-16 58.7 3.0 0.033 14.1 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEH13918.1 - 1.6e-14 54.0 2.7 0.11 12.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CEH13918.1 - 1.8e-14 53.8 8.0 0.042 14.2 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 CEH13918.1 - 5e-13 49.5 1.1 0.36 11.4 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CEH13918.1 - 4.6e-10 39.6 0.5 0.94 9.3 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 CEH13918.1 - 4.3e-07 29.9 24.6 16 5.7 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 CEH13918.1 - 5e-07 29.3 0.6 1 8.7 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 CEH13918.1 - 3.9e-06 26.9 2.8 12 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 CEH13918.1 - 4.4e-06 27.4 0.1 30 5.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain DUF2870 PF11069.8 CEH13918.1 - 5.6e-06 26.7 0.0 30 5.1 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 CEH13918.1 - 1e-05 25.3 3.8 11 5.9 0.0 4.3 4 0 0 4 4 4 0 ACT domain TmoB PF06234.12 CEH13918.1 - 1.1e-05 25.4 0.1 29 4.9 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 CEH13918.1 - 5.6e-05 23.2 3.2 6.9 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 CEH13918.1 - 0.00033 20.2 0.1 21 4.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 CEH13918.1 - 0.00036 21.1 0.9 73 4.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF493 PF04359.14 CEH13918.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 CEH13918.1 - 0.0069 16.5 0.0 91 3.3 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 CEH13918.1 - 0.011 15.9 5.3 64 3.8 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 CEH13918.1 - 0.041 13.7 9.2 43 4.1 0.1 4.4 4 0 0 4 4 4 0 FlgD Ig-like domain Tash_PEST PF07708.11 CEH13918.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 CEH13918.1 - 0.35 11.4 8.8 51 4.4 1.5 4.0 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 CEH13918.1 - 1.1 9.5 4.6 2.4e+02 2.0 0.0 4.0 4 0 0 4 4 4 0 Flagellar protein YcgR PI3K_p85B PF02192.16 CEH13918.1 - 1.2 9.0 8.5 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 CEH13918.1 - 1.2 9.3 9.9 1e+02 3.2 0.1 4.4 4 0 0 4 4 4 0 Cnl2/NKP2 family protein MRP-L46 PF11788.8 CEH13919.1 - 7.8e-22 78.3 0.2 1.3e-21 77.5 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 baeRF_family11 PF18855.1 CEH13919.1 - 0.0076 16.6 0.1 0.043 14.1 0.0 2.1 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 11 Fe-S_biosyn PF01521.20 CEH13920.1 - 5.4e-19 68.4 0.0 8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis mRNA_triPase PF02940.15 CEH13922.1 - 1.6e-38 132.6 0.0 4.7e-38 131.1 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain AHJR-like PF18743.1 CEH13922.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 REase_AHJR-like HSCB_C PF07743.13 CEH13923.1 - 3.5e-18 65.9 4.2 3.5e-18 65.9 4.2 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CEH13923.1 - 0.04 14.1 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain cwf21 PF08312.12 CEH13923.1 - 0.056 13.6 1.7 0.12 12.5 1.7 1.7 1 1 0 1 1 1 0 cwf21 domain MLANA PF14991.6 CEH13923.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A 4HBT_2 PF13279.6 CEH13926.1 - 4.1e-12 46.7 0.0 7.2e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Phosphodiest PF01663.22 CEH13927.1 - 1.3e-50 173.0 0.1 2.1e-50 172.3 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Hydrolase_like PF13242.6 CEH13927.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 CEH13927.1 - 0.071 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Mito_carr PF00153.27 CEH13928.1 - 1.2e-49 166.2 5.4 1.1e-16 60.5 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEH13928.1 - 0.13 11.4 4.2 0.16 11.1 0.1 2.7 4 0 0 4 4 4 0 Gammaproteobacterial serine protease DUF401 PF04165.12 CEH13929.1 - 0.044 13.1 0.3 0.061 12.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF401) Cyclin_C_2 PF16899.5 CEH13930.1 - 5.3e-13 49.2 1.4 1.7e-11 44.4 0.6 3.0 2 1 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 CEH13930.1 - 0.00069 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Zn_clus PF00172.18 CEH13932.1 - 1.5e-05 25.0 8.9 2.5e-05 24.3 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PFL-like PF02901.15 CEH13935.1 - 0.21 10.2 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like TAF8_C PF10406.9 CEH13936.1 - 5.3e-12 46.1 0.3 5.3e-12 46.1 0.3 2.0 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 CEH13936.1 - 0.036 14.1 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated PNGaseA PF12222.8 CEH13939.1 - 2e-89 300.4 0.0 2e-89 300.4 0.0 1.5 2 0 0 2 2 2 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Ada3 PF10198.9 CEH13940.1 - 2.9e-22 79.2 0.1 2.9e-22 79.2 0.1 1.7 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Pkinase PF00069.25 CEH13941.1 - 3.4e-68 229.9 0.0 4.4e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH13941.1 - 1.6e-49 168.5 0.0 2.2e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH13941.1 - 6.5e-05 21.9 0.0 9.9e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEH13941.1 - 0.0071 15.3 0.0 0.73 8.7 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 CEH13941.1 - 0.022 14.1 0.0 0.054 12.8 0.0 1.6 2 0 0 2 2 2 0 Kinase-like YIF1 PF03878.15 CEH13942.1 - 4.1e-91 304.8 0.1 5.2e-91 304.4 0.1 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 CEH13942.1 - 0.0045 16.7 8.1 0.01 15.6 8.1 1.7 1 1 0 1 1 1 1 Yip1 domain NTF2 PF02136.20 CEH13943.1 - 1.6e-29 102.9 0.0 2.7e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 CEH13943.1 - 0.00033 20.4 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.6 CEH13943.1 - 0.18 10.9 0.1 0.29 10.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Semialdhyde_dh PF01118.24 CEH13945.1 - 5.6e-06 26.8 0.0 1.2e-05 25.7 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 CEH13945.1 - 5.5e-05 22.8 0.0 8.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CEH13945.1 - 9.4e-05 22.4 0.1 0.00013 22.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CEH13945.1 - 0.00074 18.8 0.0 0.018 14.2 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein DXP_reductoisom PF02670.16 CEH13945.1 - 0.0036 18.0 0.0 0.006 17.3 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.19 CEH13945.1 - 0.017 14.1 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3798 PF12683.7 CEH13945.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) PEP_hydrolase PF09370.10 CEH13945.1 - 0.12 11.6 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like TsaE PF02367.17 CEH13945.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TetR_C_19 PF17924.1 CEH13945.1 - 0.13 12.9 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Phage_Gp19 PF09355.10 CEH13945.1 - 0.29 11.6 0.9 0.64 10.5 0.3 1.8 1 1 1 2 2 2 0 Phage protein Gp19/Gp15/Gp42 TIG PF01833.24 CEH13946.1 - 1.6e-12 47.3 4.3 9.4e-11 41.7 0.3 3.1 3 0 0 3 3 3 2 IPT/TIG domain Ank_3 PF13606.6 CEH13946.1 - 2.1e-08 33.8 0.9 0.013 16.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CEH13946.1 - 4.8e-08 33.1 0.4 2.6e-07 30.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEH13946.1 - 2e-07 31.5 0.1 8.4e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEH13946.1 - 4.2e-07 30.4 0.6 1e-06 29.2 0.6 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CEH13946.1 - 6.3e-06 26.4 2.6 0.097 13.2 0.4 2.7 2 0 0 2 2 2 2 Ankyrin repeat DNA_pol_phi PF04931.13 CEH13946.1 - 0.95 7.5 7.8 1.7 6.7 7.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi Antimicrobial_5 PF08026.11 CEH13947.1 - 0.022 14.8 0.3 0.03 14.4 0.3 1.3 1 0 0 1 1 1 0 Bee antimicrobial peptide WD40 PF00400.32 CEH13948.1 - 2.5e-17 62.9 9.9 5.1e-06 27.1 0.0 8.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH13948.1 - 1e-10 41.8 0.0 0.002 18.4 0.0 4.7 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CEH13948.1 - 6.3e-05 22.8 0.2 0.063 13.2 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CEH13948.1 - 0.0027 16.7 0.0 0.27 10.2 0.0 2.7 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEH13948.1 - 0.17 11.7 0.1 34 4.2 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Cpn60_TCP1 PF00118.24 CEH13949.1 - 2.4e-160 534.4 3.0 2.8e-160 534.2 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LRR_4 PF12799.7 CEH13951.1 - 3.8e-31 106.6 34.9 1.7e-08 34.6 0.1 7.7 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEH13951.1 - 2.8e-20 72.5 6.2 2.7e-07 30.3 0.0 4.0 1 1 3 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 CEH13951.1 - 6.8e-19 67.4 30.4 6.1e-08 32.3 2.3 5.8 3 2 2 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 CEH13951.1 - 0.11 12.6 25.4 18 5.7 0.0 9.5 12 1 0 12 12 12 0 Leucine Rich repeat LRR_1 PF00560.33 CEH13951.1 - 0.19 12.4 30.2 6.7 7.7 0.1 9.8 10 1 0 10 10 10 0 Leucine Rich Repeat PPP4R2 PF09184.11 CEH13951.1 - 9.7 5.7 7.8 15 5.1 7.8 1.2 1 0 0 1 1 1 0 PPP4R2 Aminotran_5 PF00266.19 CEH13952.1 - 1.8e-89 300.3 0.0 3.5e-89 299.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CEH13952.1 - 1.6e-05 24.3 0.1 2.8e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase PHD PF00628.29 CEH13953.1 - 3.8e-06 26.7 4.3 6.3e-06 26.0 4.3 1.3 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 CEH13954.1 - 0.069 13.5 0.1 3.2 8.1 0.0 3.5 2 1 1 3 3 3 0 SET domain Cyt_bd_oxida_II PF02322.15 CEH13955.1 - 0.0041 16.5 2.2 0.0041 16.5 2.2 1.9 2 0 0 2 2 2 1 Cytochrome bd terminal oxidase subunit II 7TM_GPCR_Srd PF10317.9 CEH13955.1 - 0.0077 15.5 0.7 0.012 14.9 0.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd FtsX PF02687.21 CEH13955.1 - 0.017 15.6 5.8 0.098 13.1 0.5 2.2 2 0 0 2 2 2 0 FtsX-like permease family DUF21 PF01595.20 CEH13955.1 - 1 9.1 6.7 1 9.0 5.1 1.7 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain DUF2207 PF09972.9 CEH13955.1 - 9.7 4.8 10.2 45 2.6 10.2 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ACPS PF01648.20 CEH13956.1 - 2.8e-10 40.3 0.0 7.3e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Cyclin PF08613.11 CEH13956.1 - 3.6e-09 37.2 3.3 4.8e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 Cyclin BolA PF01722.18 CEH13957.1 - 5.9e-16 58.5 0.0 1.1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein ResIII PF04851.15 CEH13958.1 - 4.4e-21 75.6 0.0 1.6e-20 73.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEH13958.1 - 1.2e-15 57.8 0.0 4.3e-15 56.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEH13958.1 - 2.3e-12 47.0 0.0 4.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CEH13958.1 - 3.6e-06 26.8 0.0 6.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 CEH13958.1 - 0.0022 17.3 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 CEH13958.1 - 0.021 14.4 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CEH13958.1 - 0.025 14.8 0.0 0.077 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CEH13958.1 - 0.026 13.6 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 CEH13958.1 - 0.031 14.0 0.1 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 CEH13958.1 - 0.077 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_11 PF13086.6 CEH13958.1 - 3.3 7.4 10.0 5.9 6.6 0.0 3.3 3 1 1 4 4 4 0 AAA domain Lipase_3 PF01764.25 CEH13960.1 - 5.3e-08 32.8 0.0 5e-07 29.7 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) SAM_decarbox PF01536.16 CEH13962.1 - 1.1e-117 393.0 0.0 3e-117 391.6 0.0 1.6 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DOPA_dioxygen PF08883.11 CEH13962.1 - 0.072 13.3 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 Dopa 4,5-dioxygenase family Abhydrolase_4 PF08386.10 CEH13963.1 - 5.7e-11 42.4 0.0 3e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 CEH13963.1 - 0.046 13.0 0.0 0.85 8.8 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Shisa PF13908.6 CEH13964.1 - 0.019 15.2 0.1 0.033 14.5 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator IHABP4_N PF16174.5 CEH13964.1 - 2.1 8.9 7.7 1.7 9.2 5.5 1.7 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Nup54 PF13874.6 CEH13966.1 - 1.6e-28 99.6 7.7 1.6e-28 99.6 7.7 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 CEH13966.1 - 2.3e-05 24.2 0.0 5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Nup54 C-terminal interacting domain Laminin_II PF06009.12 CEH13966.1 - 0.036 14.1 1.4 0.097 12.7 1.4 1.8 1 0 0 1 1 1 0 Laminin Domain II XPG_I PF00867.18 CEH13967.1 - 3e-16 59.5 0.0 2.5e-15 56.6 0.0 2.2 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CEH13967.1 - 0.00056 20.3 0.0 0.0017 18.8 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain GEN1_C PF18380.1 CEH13967.1 - 0.0023 18.8 0.1 0.0023 18.8 0.1 3.1 4 1 0 4 4 4 1 Holliday junction resolvase Gen1 C-terminal domain Se-cys_synth_N PF12390.8 CEH13967.1 - 0.03 14.5 0.2 0.11 12.7 0.2 2.1 1 0 0 1 1 1 0 Selenocysteine synthase N terminal EHN PF06441.12 CEH13968.1 - 4.7e-27 94.5 0.0 8.8e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CEH13968.1 - 3.7e-06 26.8 0.2 6.7e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH13968.1 - 0.00029 21.5 0.2 0.00052 20.7 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.25 CEH13969.1 - 2.4e-65 220.6 0.0 2.8e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH13969.1 - 2.1e-30 105.9 0.0 1.1e-29 103.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH13969.1 - 6.6e-05 22.4 0.1 0.00018 20.9 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEH13969.1 - 0.0001 21.7 0.1 0.00017 21.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CEH13969.1 - 0.002 17.8 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CEH13969.1 - 0.0029 17.6 0.2 0.87 9.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEH13969.1 - 0.0037 16.3 0.0 0.0053 15.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CEH13969.1 - 0.06 13.0 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 zf-C2H2 PF00096.26 CEH13971.1 - 1.9e-05 24.9 4.0 0.057 13.9 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEH13971.1 - 0.00089 19.9 1.1 2.7 9.1 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Tyr_Deacylase PF02580.16 CEH13972.1 - 4.2e-44 150.6 0.0 3.2e-43 147.7 0.0 1.9 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase 4HBT PF03061.22 CEH13973.1 - 8.4e-17 61.3 1.6 2.2e-08 34.3 0.1 2.7 2 0 0 2 2 2 2 Thioesterase superfamily NolX PF05819.11 CEH13973.1 - 0.075 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 NolX protein SET PF00856.28 CEH13974.1 - 0.12 12.8 0.0 0.32 11.4 0.0 2.0 1 1 0 1 1 1 0 SET domain Spo7 PF03907.13 CEH13975.1 - 3.8e-29 101.8 0.4 4.5e-25 88.4 0.1 2.3 2 0 0 2 2 2 2 Spo7-like protein Tmemb_18A PF09771.9 CEH13975.1 - 0.35 11.3 0.1 0.35 11.3 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 188 PPR_2 PF13041.6 CEH13977.1 - 1.8e-35 120.9 0.0 3.5e-11 43.1 0.0 6.7 6 1 1 7 7 7 4 PPR repeat family PPR PF01535.20 CEH13977.1 - 5.5e-29 98.4 1.3 3e-05 24.0 0.0 11.0 13 0 0 13 13 13 7 PPR repeat PPR_1 PF12854.7 CEH13977.1 - 4.4e-18 64.7 0.0 0.0055 16.4 0.0 8.1 8 0 0 8 8 8 4 PPR repeat PPR_3 PF13812.6 CEH13977.1 - 1.2e-17 63.7 0.0 2e-05 24.6 0.0 6.1 5 1 1 6 6 6 3 Pentatricopeptide repeat domain PPR_long PF17177.4 CEH13977.1 - 1.4e-07 31.1 0.0 0.032 13.6 0.0 4.7 2 2 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CEH13977.1 - 0.015 15.8 10.9 1.1 9.8 0.0 6.1 7 1 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEH13977.1 - 0.061 14.2 24.2 5.4 8.1 0.1 10.1 11 1 1 12 12 12 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEH13977.1 - 0.3 11.0 2.8 61 3.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 CEH13977.1 - 0.35 11.6 6.1 3.3 8.6 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEH13977.1 - 0.42 11.3 14.0 1.2 9.8 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 CEH13978.1 - 1.5e-11 44.0 0.3 2.4e-08 33.6 0.2 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 CEH13978.1 - 1.2e-09 38.1 0.3 8.9e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.12 CEH13978.1 - 5.3e-08 31.9 1.0 0.0002 20.2 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 CEH13978.1 - 6e-07 30.3 2.6 1.9e-06 28.6 2.5 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEH13978.1 - 1.4e-06 28.1 0.2 6.2e-06 26.0 0.3 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CEH13978.1 - 1.6e-05 24.6 0.4 2.4e-05 24.1 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 CEH13978.1 - 0.00012 21.6 0.2 0.0013 18.3 0.2 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1100 PF06500.11 CEH13978.1 - 0.0024 16.8 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.11 CEH13978.1 - 0.039 13.9 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 CEH13978.1 - 0.23 9.9 0.1 2 6.8 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II NAT PF04768.13 CEH13980.1 - 1.4e-46 158.3 0.0 2.7e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 CEH13980.1 - 6e-29 101.3 0.0 1.9e-28 99.7 0.0 2.0 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 CEH13980.1 - 5.3e-27 94.7 0.0 1.2e-26 93.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 CEH13980.1 - 6.5e-08 32.9 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 CEH13980.1 - 0.032 14.4 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pam16 PF03656.13 CEH13980.1 - 0.52 10.3 0.0 0.52 10.3 0.0 2.5 3 0 0 3 3 3 0 Pam16 CENP-F_leu_zip PF10473.9 CEH13981.1 - 0.0044 17.1 1.5 0.0044 17.1 1.5 2.3 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mitofilin PF09731.9 CEH13981.1 - 0.0058 15.5 2.4 0.0058 15.5 2.4 1.8 2 0 0 2 2 2 1 Mitochondrial inner membrane protein Atg14 PF10186.9 CEH13981.1 - 0.012 14.7 0.2 0.012 14.7 0.2 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 CEH13981.1 - 0.017 15.3 4.3 0.46 10.7 0.5 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tropomyosin_1 PF12718.7 CEH13981.1 - 0.065 13.4 11.2 0.16 12.2 3.3 2.2 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.11 CEH13981.1 - 0.067 12.1 9.1 0.029 13.2 1.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein FlxA PF14282.6 CEH13981.1 - 0.14 12.2 2.4 0.2 11.7 0.4 2.3 2 1 0 2 2 2 0 FlxA-like protein DUF4407 PF14362.6 CEH13981.1 - 0.36 10.1 8.3 1.1 8.6 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Filament PF00038.21 CEH13981.1 - 0.46 10.0 8.2 2.5 7.6 1.6 2.4 2 0 0 2 2 2 0 Intermediate filament protein DUF4140 PF13600.6 CEH13981.1 - 2.9 8.4 11.1 15 6.1 0.1 3.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.14 CEH13981.1 - 5.4 7.4 5.5 22 5.4 0.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Med9 PF07544.13 CEH13981.1 - 6.4 6.9 8.4 13 5.9 0.5 3.3 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 S1 PF00575.23 CEH13982.1 - 1.2e-30 105.6 4.3 4.5e-10 39.7 0.3 9.4 11 0 0 11 11 11 4 S1 RNA binding domain Suf PF05843.14 CEH13982.1 - 2.3e-07 31.1 0.0 2.3e-07 31.1 0.0 4.1 2 1 3 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CEH13982.1 - 1e-06 29.1 1.5 0.95 10.5 0.0 5.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEH13982.1 - 1.1e-06 29.1 0.1 0.58 10.7 0.0 4.7 3 1 3 6 6 6 3 Tetratricopeptide repeat NRDE-2 PF08424.10 CEH13982.1 - 3.7e-06 26.3 9.6 9.5e-06 24.9 1.0 2.8 1 1 2 3 3 3 2 NRDE-2, necessary for RNA interference TPR_12 PF13424.6 CEH13982.1 - 7.1e-05 23.0 0.0 0.067 13.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEH13982.1 - 0.00029 21.3 2.0 0.0025 18.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 CEH13982.1 - 0.003 17.5 3.9 2.3 8.2 0.0 5.6 7 0 0 7 7 7 1 RNase II-type exonuclease C-terminal S1 domain TPR_2 PF07719.17 CEH13982.1 - 0.005 16.9 0.4 7.7 6.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat RPA43_OB PF17875.1 CEH13982.1 - 1.2 9.8 0.0 1.2 9.8 0.0 6.8 5 1 1 6 6 6 0 RPA43 OB domain in RNA Pol I RNase_PH PF01138.21 CEH13983.1 - 3.1e-12 47.1 0.0 6.1e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEH13983.1 - 4.6e-05 23.4 0.0 7.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 LNS2 PF08235.13 CEH13984.1 - 2.1e-98 328.3 0.0 8.9e-76 254.3 0.0 2.2 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CEH13984.1 - 1.2e-28 99.1 0.1 3.7e-17 62.1 0.0 2.7 3 0 0 3 3 3 2 lipin, N-terminal conserved region Lipin_mid PF16876.5 CEH13984.1 - 3.9e-14 52.6 0.0 7.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Creatinase_N_2 PF16189.5 CEH13985.1 - 2.7e-44 151.1 0.0 1.6e-42 145.4 0.0 2.5 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CEH13985.1 - 3.5e-44 151.0 0.0 5.4e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CEH13985.1 - 2e-22 79.0 0.1 5.5e-22 77.6 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CEH13985.1 - 1.3e-20 74.4 0.1 1.2e-17 64.8 0.0 2.6 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Yip1 PF04893.17 CEH13986.1 - 1.1e-08 35.0 11.0 1.9e-08 34.2 11.0 1.4 1 0 0 1 1 1 1 Yip1 domain MFS_1 PF07690.16 CEH13988.1 - 2.5e-13 49.7 50.6 2.4e-08 33.3 26.9 3.0 2 1 2 4 4 4 2 Major Facilitator Superfamily CRPA PF05745.11 CEH13988.1 - 0.056 13.4 0.4 6.5 6.8 0.3 3.3 2 1 1 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Pox_A14 PF05767.12 CEH13988.1 - 0.44 10.7 4.9 0.096 12.9 0.4 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Condensation PF00668.20 CEH13989.1 - 1.2e-86 291.3 0.0 8.3e-48 163.2 0.0 3.4 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 CEH13989.1 - 3.6e-80 269.6 0.0 5.2e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CEH13989.1 - 5.7e-23 81.0 1.6 1.6e-07 31.6 0.2 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CEH13989.1 - 0.002 19.1 0.0 0.0069 17.3 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YAcAr PF10686.9 CEH13989.1 - 0.0023 17.8 0.0 0.0088 16.0 0.0 2.0 1 0 0 1 1 1 1 YspA, cpYpsA-related SLOG family HTH_23 PF13384.6 CEH13989.1 - 0.12 12.2 0.2 0.45 10.4 0.2 2.1 1 0 0 1 1 1 0 Homeodomain-like domain ECH_1 PF00378.20 CEH13990.1 - 6.8e-44 150.1 0.0 8.6e-40 136.6 0.0 2.7 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEH13990.1 - 5.3e-24 85.3 0.0 5.3e-20 72.2 0.0 2.6 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase DUF1631 PF07793.11 CEH13990.1 - 0.02 13.4 0.7 0.065 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) SPX PF03105.19 CEH13990.1 - 0.12 12.2 1.7 0.16 11.9 1.7 1.1 1 0 0 1 1 1 0 SPX domain Acetyltransf_8 PF13523.6 CEH13991.1 - 3.6e-25 88.3 0.0 7.4e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.13 CEH13992.1 - 1.5e-17 64.1 0.6 5.5e-17 62.3 0.1 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 CEH13992.1 - 1.3e-09 37.9 0.0 1.6e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 CEH13992.1 - 1.9e-06 27.7 0.0 3.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 CEH13992.1 - 1.1e-05 25.0 0.4 0.069 12.6 0.5 2.6 2 1 1 3 3 3 2 Prolyl oligopeptidase family COesterase PF00135.28 CEH13992.1 - 0.0085 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 CEH13992.1 - 0.013 14.2 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 CEH13992.1 - 0.11 12.1 0.3 0.23 11.1 0.3 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold ABC_membrane PF00664.23 CEH13993.1 - 1.4e-67 228.2 16.5 1.7e-36 126.3 5.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEH13993.1 - 1.1e-47 162.0 0.0 5.2e-26 91.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 CEH13993.1 - 8e-08 32.9 0.1 0.0061 17.0 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain SMC_N PF02463.19 CEH13993.1 - 2.1e-07 30.6 0.1 0.099 12.1 0.0 3.7 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEH13993.1 - 1.7e-06 27.7 0.4 0.019 14.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 CEH13993.1 - 1.7e-06 27.7 0.4 0.0067 16.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEH13993.1 - 3.1e-06 27.5 0.8 0.016 15.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CEH13993.1 - 4.1e-06 26.8 0.0 0.042 13.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CEH13993.1 - 1.6e-05 24.8 6.2 0.17 11.6 0.1 3.3 3 0 0 3 3 3 3 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CEH13993.1 - 2.9e-05 24.1 1.2 0.15 12.2 0.2 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase TsaE PF02367.17 CEH13993.1 - 9.4e-05 22.4 0.3 0.55 10.2 0.1 3.3 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 CEH13993.1 - 0.00014 22.5 0.2 0.3 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CEH13993.1 - 0.00014 21.2 0.6 0.2 10.9 0.2 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 CEH13993.1 - 0.00017 21.4 2.9 0.16 11.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 CEH13993.1 - 0.00028 21.4 0.2 1.3 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CEH13993.1 - 0.00045 20.0 0.4 0.29 10.9 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 CEH13993.1 - 0.00057 19.4 0.5 0.23 11.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 CEH13993.1 - 0.00057 20.0 5.4 0.0049 17.0 0.5 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 CEH13993.1 - 0.00091 19.6 0.1 1.5 9.2 0.0 3.0 3 0 0 3 3 2 1 RNA helicase T2SSE PF00437.20 CEH13993.1 - 0.0023 17.0 0.0 0.42 9.6 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein cobW PF02492.19 CEH13993.1 - 0.0027 17.3 1.4 0.81 9.2 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 CEH13993.1 - 0.0041 16.5 0.3 0.053 12.9 0.1 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 CEH13993.1 - 0.0059 15.6 1.9 0.27 10.1 0.2 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 CEH13993.1 - 0.009 16.1 1.6 0.8 9.7 0.4 2.4 2 0 0 2 2 2 1 Dynamin family ATPase_2 PF01637.18 CEH13993.1 - 0.0096 15.9 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 CEH13993.1 - 0.01 16.3 0.9 2.2 8.7 0.1 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CEH13993.1 - 0.011 15.6 2.0 2.7 7.9 0.3 2.5 2 0 0 2 2 2 0 NACHT domain MobB PF03205.14 CEH13993.1 - 0.011 15.6 0.7 0.99 9.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 CEH13993.1 - 0.017 15.3 3.2 3.9 7.6 0.1 3.1 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 CEH13993.1 - 0.022 14.0 1.0 2.7 7.1 0.1 2.7 3 0 0 3 3 2 0 NB-ARC domain AAA_21 PF13304.6 CEH13993.1 - 0.032 14.0 0.9 3.1 7.5 0.1 2.6 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 CEH13993.1 - 0.039 13.8 1.2 2.2 8.2 0.1 2.9 3 0 0 3 3 2 0 NTPase dNK PF01712.19 CEH13993.1 - 0.092 12.6 1.5 6.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase DEAD PF00270.29 CEH13993.1 - 0.093 12.5 1.5 6.4 6.5 0.1 3.6 4 0 0 4 4 4 0 DEAD/DEAH box helicase Ploopntkinase3 PF18751.1 CEH13993.1 - 0.14 12.1 1.0 7.9 6.3 0.1 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 CLP1_P PF16575.5 CEH13993.1 - 0.15 11.9 0.2 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 CEH13993.1 - 0.15 11.6 4.0 1.7 8.2 0.1 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 CEH13993.1 - 0.17 12.1 0.9 27 5.0 0.1 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 CEH13993.1 - 0.18 11.8 0.9 69 3.4 0.1 3.7 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CEH13993.1 - 0.19 11.4 0.4 7.9 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 CEH13993.1 - 0.2 10.6 0.7 10 4.9 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain DUF3584 PF12128.8 CEH13993.1 - 0.2 9.2 0.2 0.3 8.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PduV-EutP PF10662.9 CEH13993.1 - 0.25 11.1 0.7 16 5.2 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 CEH13993.1 - 0.36 9.8 3.3 0.78 8.7 0.1 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 CEH13993.1 - 0.95 9.2 3.0 1.8 8.3 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 CEH13993.1 - 1.3 9.2 7.0 2.1 8.6 0.2 3.1 3 0 0 3 3 3 0 AAA domain NTF2 PF02136.20 CEH13995.1 - 0.051 14.2 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain PEN-2 PF10251.9 CEH13997.1 - 0.028 14.8 0.3 0.051 14.0 0.3 1.3 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Coprogen_oxidas PF01218.18 CEH13998.1 - 2.5e-117 390.8 0.0 5.6e-117 389.7 0.0 1.5 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase BAF PF02961.14 CEH13998.1 - 0.12 12.9 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 Barrier to autointegration factor START PF01852.19 CEH13999.1 - 2.8e-07 30.2 0.1 3.9e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 START domain AIRC PF00731.20 CEH14000.1 - 8.9e-62 207.0 0.3 1.8e-61 206.1 0.3 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 CEH14000.1 - 1e-51 174.9 0.0 1.7e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 CEH14000.1 - 3.1e-19 68.4 0.0 7.3e-19 67.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 CEH14000.1 - 0.00018 21.0 0.0 0.00035 20.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 CEH14000.1 - 0.00054 19.6 0.0 0.002 17.7 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 3HCDH_N PF02737.18 CEH14000.1 - 0.0028 17.6 0.4 0.0062 16.4 0.4 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEH14000.1 - 0.061 12.6 0.5 0.17 11.2 0.5 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SGL PF08450.12 CEH14001.1 - 1e-25 90.8 0.1 2.9e-25 89.3 0.1 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 CEH14001.1 - 0.0031 17.6 0.0 0.011 15.8 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 CEH14001.1 - 0.021 15.0 0.0 0.054 13.7 0.0 1.8 1 1 0 1 1 1 0 Arylesterase NHL PF01436.21 CEH14001.1 - 0.078 13.1 1.5 11 6.3 0.0 3.6 4 0 0 4 4 4 0 NHL repeat Fasciclin PF02469.22 CEH14002.1 - 9.9e-14 51.7 0.0 1.7e-10 41.2 0.0 3.8 3 1 0 3 3 3 2 Fasciclin domain FH2 PF02181.23 CEH14003.1 - 4.7e-79 266.2 0.0 2e-77 260.9 0.0 2.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CEH14003.1 - 6.7e-24 84.5 0.0 1.6e-18 67.0 0.0 2.7 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CEH14003.1 - 1.9e-05 24.4 0.1 6.2e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 Diaphanous FH3 Domain HMMR_N PF15905.5 CEH14003.1 - 0.28 10.6 11.4 0.14 11.6 0.9 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 CEH14003.1 - 0.41 10.1 15.4 0.13 11.7 11.8 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 Gon7 PF08738.10 CEH14003.1 - 0.75 9.9 6.9 2.6 8.2 0.8 3.4 2 1 1 3 3 3 0 Gon7 family FAM184 PF15665.5 CEH14003.1 - 5.3 6.8 17.5 0.96 9.2 0.1 2.9 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B CtIP_N PF10482.9 CEH14003.1 - 7.9 6.6 7.3 52 3.9 0.0 3.4 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain RCC1 PF00415.18 CEH14004.1 - 1.3e-21 77.0 1.2 0.00064 20.3 0.0 6.7 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEH14004.1 - 1.1e-07 31.4 3.9 0.17 11.7 0.1 5.6 6 1 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat SBP_bac_10 PF07596.11 CEH14004.1 - 0.00021 21.4 0.6 0.00038 20.5 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1559) IMPDH PF00478.25 CEH14005.1 - 4.5e-130 433.7 2.1 5.2e-130 433.5 2.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CEH14005.1 - 2.7e-15 56.5 0.2 1.1e-06 29.0 0.0 3.2 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 CEH14005.1 - 1.7e-09 37.2 0.8 5.7e-09 35.5 0.8 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CEH14005.1 - 4.4e-08 32.9 1.6 1.3e-07 31.3 1.6 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 CEH14005.1 - 2.5e-05 23.8 15.5 0.00039 19.9 8.9 3.4 3 1 0 3 3 3 2 Nitronate monooxygenase ThiG PF05690.14 CEH14005.1 - 0.00098 18.5 1.5 0.0023 17.3 1.5 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 CEH14005.1 - 0.015 14.7 0.9 0.22 10.9 0.2 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DUF561 PF04481.12 CEH14005.1 - 0.017 14.3 0.3 0.36 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) EAL PF00563.20 CEH14005.1 - 0.055 13.0 0.1 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 EAL domain YpsA PF06908.11 CEH14005.1 - 0.098 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Dus PF01207.17 CEH14005.1 - 0.12 11.5 1.0 0.89 8.6 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 CEH14005.1 - 1 8.5 3.7 0.49 9.6 0.4 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase GTP_EFTU PF00009.27 CEH14007.1 - 2.3e-43 148.0 0.0 3.5e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEH14007.1 - 7.5e-32 110.0 1.7 2e-31 108.6 0.1 2.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEH14007.1 - 1.3e-08 35.1 2.0 3.2e-08 33.9 2.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEH14007.1 - 0.0015 18.6 0.0 0.0079 16.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 CEH14007.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein GTP_EFTU_D4 PF14578.6 CEH14007.1 - 0.38 10.7 2.6 0.62 10.0 0.6 2.4 4 0 0 4 4 4 0 Elongation factor Tu domain 4 MRP-S33 PF08293.11 CEH14009.1 - 1.4e-17 63.7 0.0 1.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PGM_PMM_I PF02878.16 CEH14010.1 - 4.8e-17 62.0 0.0 5.9e-08 32.5 0.0 3.3 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CEH14010.1 - 5.7e-13 48.8 0.1 3e-12 46.5 0.1 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CEH14010.1 - 0.0043 17.2 0.0 0.0093 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CEH14010.1 - 0.04 14.5 0.1 0.24 12.0 0.1 2.5 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SR-25 PF10500.9 CEH14011.1 - 0.13 11.8 6.9 0.21 11.2 6.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ArfGap PF01412.18 CEH14013.1 - 1.3e-35 121.9 0.4 3.9e-35 120.4 0.4 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 CEH14013.1 - 7e-09 36.2 0.0 2.2e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 PH domain BAR_3 PF16746.5 CEH14013.1 - 0.0013 18.4 0.4 0.0013 18.4 0.4 1.9 2 0 0 2 2 2 1 BAR domain of APPL family Pyr_redox_2 PF07992.14 CEH14014.1 - 1.1e-38 133.2 0.0 1e-37 129.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEH14014.1 - 9.5e-12 45.3 0.0 3.1e-10 40.5 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TAF6_C PF07571.13 CEH14015.1 - 0.0048 17.2 0.0 0.0049 17.2 0.0 1.1 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain DUF4112 PF13430.6 CEH14016.1 - 7.8e-32 109.7 0.1 9.9e-32 109.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) TctA PF01970.16 CEH14016.1 - 0.027 13.2 0.0 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family TFIIS_C PF01096.18 CEH14018.1 - 9.2e-12 44.6 0.6 9.2e-12 44.6 0.6 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CEH14018.1 - 4.1e-10 39.4 1.1 4.1e-10 39.4 1.1 3.3 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CEH14018.1 - 0.0038 17.2 9.0 0.022 14.7 1.9 2.4 2 1 0 2 2 2 2 Transposase zinc-ribbon domain DUF2197 PF09963.9 CEH14018.1 - 0.007 16.6 5.5 0.025 14.8 0.9 2.5 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) Lar_restr_allev PF14354.6 CEH14018.1 - 0.01 16.2 0.9 0.01 16.2 0.9 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 CEH14018.1 - 0.024 14.7 7.8 0.23 11.5 0.3 2.8 2 1 1 3 3 3 0 Double zinc ribbon zf-CSL PF05207.13 CEH14018.1 - 0.04 13.6 6.0 1.4 8.7 0.2 3.0 2 1 1 3 3 3 0 CSL zinc finger CDH-cyt PF16010.5 CEH14018.1 - 0.041 13.6 0.1 0.041 13.6 0.1 1.4 2 0 0 2 2 2 0 Cytochrome domain of cellobiose dehydrogenase DUF3268 PF11672.8 CEH14018.1 - 0.047 14.0 3.5 1.8 8.9 0.3 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 CEH14018.1 - 0.049 13.7 10.2 2.6 8.2 0.4 3.6 4 0 0 4 4 4 0 Zinc ribbon domain NMD3 PF04981.13 CEH14018.1 - 0.051 13.0 3.1 0.69 9.3 0.3 2.1 2 0 0 2 2 2 0 NMD3 family zf_UBZ PF18439.1 CEH14018.1 - 0.058 13.0 5.1 2.5 7.8 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 CEH14018.1 - 0.16 12.0 2.8 0.17 11.9 0.3 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 CEH14018.1 - 0.23 11.0 3.5 0.61 9.7 1.0 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding IBR PF01485.21 CEH14018.1 - 0.44 10.8 9.5 2.3e+02 2.1 9.5 2.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-TFIIB PF13453.6 CEH14018.1 - 0.52 9.7 9.9 0.82 9.1 0.6 3.2 2 2 1 3 3 3 0 Transcription factor zinc-finger C1_1 PF00130.22 CEH14018.1 - 0.87 9.5 9.4 0.76 9.7 0.3 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_SprT PF17283.2 CEH14018.1 - 4.6 7.2 13.7 12 5.9 0.1 3.4 3 1 0 3 3 3 0 SprT-like zinc ribbon domain Pkinase PF00069.25 CEH14019.1 - 1.2e-53 182.1 0.0 6e-53 179.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH14019.1 - 1.2e-24 87.0 0.0 6.5e-24 84.6 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase PH_3 PF14593.6 CEH14019.1 - 2.9e-10 40.2 0.0 0.00042 20.4 0.0 2.3 2 0 0 2 2 2 2 PH domain Kinase-like PF14531.6 CEH14019.1 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEH14019.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cmc1 PF08583.10 CEH14020.1 - 1.6e-16 60.1 1.1 1.9e-16 59.9 1.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 CEH14020.1 - 0.0057 16.4 0.4 0.0074 16.0 0.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 CEH14020.1 - 0.039 14.0 2.1 3.3 7.8 0.2 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GCK PF07802.11 CEH14020.1 - 0.063 13.7 1.3 0.099 13.1 0.7 1.6 1 1 1 2 2 2 0 GCK domain GatB_N PF02934.15 CEH14022.1 - 1.2e-44 152.8 0.4 1.8e-44 152.2 0.0 1.4 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CEH14022.1 - 4.3e-18 65.6 0.0 2.3e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 GatB domain YqeY PF09424.10 CEH14022.1 - 0.085 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Yqey-like protein PI-PLC-X PF00388.19 CEH14023.1 - 7.8e-57 190.9 0.0 1.6e-56 189.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CEH14023.1 - 6.6e-36 123.2 0.0 1.7e-35 121.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.6 CEH14023.1 - 6.2e-06 26.6 0.1 1.8e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair C2 PF00168.30 CEH14023.1 - 0.0064 16.8 0.0 0.62 10.4 0.0 2.7 2 0 0 2 2 2 1 C2 domain EF-hand_1 PF00036.32 CEH14023.1 - 0.021 14.3 0.0 4.9 6.9 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.6 CEH14023.1 - 0.18 11.7 0.2 0.69 9.8 0.1 2.0 1 1 1 2 2 2 0 EF hand HA2 PF04408.23 CEH14027.1 - 9.3e-12 45.2 0.9 2e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CEH14027.1 - 9e-08 32.4 0.0 2.7e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CEH14027.1 - 2.8e-05 24.4 0.0 9e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CEH14027.1 - 0.0006 19.6 0.4 1.4 8.7 0.2 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_19 PF13245.6 CEH14027.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEH14027.1 - 0.012 15.9 0.3 0.19 12.0 0.3 2.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 CEH14027.1 - 0.15 12.1 0.2 8.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UFD1 PF03152.14 CEH14028.1 - 3.4e-64 215.5 0.0 4.3e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF1295 PF06966.12 CEH14029.1 - 9.4e-52 175.9 1.3 1.4e-51 175.3 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 CEH14029.1 - 8.1e-06 25.9 1.9 8.6e-06 25.8 0.0 2.0 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 CEH14029.1 - 0.003 17.9 2.3 0.0041 17.5 0.0 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 CEH14029.1 - 0.0089 16.4 0.7 0.018 15.4 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Mito_carr PF00153.27 CEH14030.1 - 1.5e-12 47.3 0.2 1.7e-10 40.7 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein LacY_symp PF01306.19 CEH14030.1 - 0.19 10.5 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 LacY proton/sugar symporter Acyl-CoA_dh_2 PF08028.11 CEH14031.1 - 4.1e-05 23.9 0.1 6.4e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 CEH14031.1 - 0.0046 17.2 0.0 0.0071 16.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SKG6 PF08693.10 CEH14033.1 - 0.024 14.0 0.7 0.024 14.0 0.7 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF4514 PF14986.6 CEH14033.1 - 0.19 11.7 0.1 0.37 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) HA2 PF04408.23 CEH14034.1 - 1.1e-23 83.6 0.1 1.1e-23 83.6 0.1 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEH14034.1 - 1.1e-21 77.0 0.0 2.3e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEH14034.1 - 6.4e-14 52.2 0.0 2.4e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEH14034.1 - 3.3e-07 30.2 0.1 6.5e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase S1 PF00575.23 CEH14034.1 - 1.4e-06 28.6 0.0 3.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 CEH14034.1 - 0.0004 20.7 0.0 0.001 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEH14034.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CEH14034.1 - 0.0048 16.0 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 CEH14034.1 - 0.013 14.8 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CEH14034.1 - 0.02 15.2 0.1 0.037 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEH14034.1 - 0.025 15.1 0.3 0.71 10.4 0.1 3.0 2 1 0 2 2 1 0 ABC transporter Microtub_bd PF16796.5 CEH14034.1 - 0.043 13.8 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding Flavi_DEAD PF07652.14 CEH14034.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.16 CEH14034.1 - 0.065 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 CEH14034.1 - 0.16 12.0 0.0 6.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Lipase_3 PF01764.25 CEH14035.1 - 4e-11 43.0 0.0 9.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CEH14035.1 - 0.12 12.9 2.9 0.12 13.0 0.8 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family MOSP_N PF02707.16 CEH14037.1 - 0.097 12.4 0.1 0.15 11.8 0.1 1.3 1 1 0 1 1 1 0 Major Outer Sheath Protein N-terminal region Thaumatin PF00314.17 CEH14038.1 - 7e-11 42.2 0.7 2.9e-09 36.9 0.5 2.0 2 0 0 2 2 2 2 Thaumatin family PHO4 PF01384.20 CEH14039.1 - 1.3e-114 382.8 16.2 1.5e-114 382.6 16.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family Asp_protease_2 PF13650.6 CEH14040.1 - 7.7e-05 23.3 0.5 0.54 10.9 0.1 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CEH14040.1 - 0.025 15.1 0.1 1.4 9.5 0.0 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Sas10 PF09368.10 CEH14041.1 - 0.034 14.6 0.6 0.041 14.4 0.6 1.1 1 0 0 1 1 1 0 Sas10 C-terminal domain Bromo_TP PF07524.13 CEH14041.1 - 0.092 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Bromodomain associated ABM PF03992.16 CEH14052.1 - 0.00012 22.1 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase RPN7 PF10602.9 CEH14052.1 - 0.032 13.9 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 26S proteasome subunit RPN7 ADH_zinc_N PF00107.26 CEH14053.1 - 1.1e-15 57.8 0.7 1.1e-15 57.8 0.7 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEH14053.1 - 2.3e-15 57.8 0.1 4.6e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH14053.1 - 1.1e-07 31.7 0.1 4.9e-07 29.6 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 CEH14053.1 - 0.0026 17.5 0.4 0.0041 16.9 0.4 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N_2 PF16884.5 CEH14053.1 - 0.051 13.5 0.1 0.13 12.2 0.1 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase SAP18 PF06487.12 CEH14054.1 - 0.038 14.2 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Sin_N PF04801.13 CEH14055.1 - 1e-32 113.9 0.0 1.6e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region Ribosomal_L21p PF00829.21 CEH14056.1 - 1.8e-17 63.5 0.3 5.8e-10 39.3 0.6 2.2 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein Peptidase_C1_2 PF03051.15 CEH14057.1 - 2e-134 448.7 0.3 7.5e-134 446.8 0.3 1.7 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 CEH14057.1 - 3.1e-06 27.4 0.2 0.0074 16.4 0.2 2.9 2 1 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.13 CEH14057.1 - 0.0086 15.3 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Phage portal protein, lambda family DAO PF01266.24 CEH14058.1 - 1.8e-32 113.3 0.0 2.4e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEH14058.1 - 9.7e-07 28.9 0.4 1.8e-05 24.9 0.1 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CEH14058.1 - 3.5e-06 26.4 0.1 0.023 13.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 CEH14058.1 - 3.7e-06 27.4 0.0 0.0028 18.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEH14058.1 - 0.0014 18.0 0.1 0.02 14.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CEH14058.1 - 0.0022 17.3 0.1 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CEH14058.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 CEH14058.1 - 0.038 13.6 0.1 0.16 11.6 0.0 2.1 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 CEH14058.1 - 0.039 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 CEH14058.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Amino_oxidase PF01593.24 CEH14058.1 - 0.083 12.2 0.1 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 CEH14058.1 - 0.093 11.8 0.0 0.68 8.9 0.0 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 CEH14058.1 - 0.13 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 CEH14058.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TAL_effector PF03377.13 CEH14058.1 - 0.19 12.1 0.9 11 6.5 0.0 2.6 2 0 0 2 2 2 0 TAL effector repeat UDPG_MGDP_dh_N PF03721.14 CEH14058.1 - 0.21 11.2 0.1 0.4 10.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sen15 PF09631.10 CEH14059.1 - 1.9e-14 53.8 0.1 9.2e-14 51.6 0.1 2.0 1 1 0 1 1 1 1 Sen15 protein DUF3246 PF11596.8 CEH14059.1 - 0.0093 15.4 0.6 0.011 15.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) CENP-B_dimeris PF09026.10 CEH14059.1 - 0.015 15.6 7.7 0.03 14.7 7.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 CEH14059.1 - 0.026 14.4 0.9 0.036 13.9 0.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PI3K_1B_p101 PF10486.9 CEH14059.1 - 0.04 11.7 0.6 0.045 11.5 0.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM176 PF14851.6 CEH14059.1 - 0.042 13.5 0.5 0.063 12.9 0.5 1.3 1 0 0 1 1 1 0 FAM176 family DUF3245 PF11595.8 CEH14059.1 - 0.4 11.1 5.2 0.71 10.3 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) NOA36 PF06524.12 CEH14059.1 - 0.66 9.2 7.5 0.85 8.9 7.5 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 CEH14059.1 - 2.6 8.3 7.2 5.2 7.4 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 CEH14059.1 - 3 5.8 5.9 4 5.4 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi PAM2 PF07145.15 CEH14060.1 - 0.13 12.0 9.5 2.3 8.1 0.0 4.1 5 0 0 5 5 5 0 Ataxin-2 C-terminal region Baculo_PEP_C PF04513.12 CEH14060.1 - 0.37 10.8 7.1 12 6.0 1.0 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PUF PF00806.19 CEH14061.1 - 3.5e-64 209.0 10.6 3.6e-09 35.8 0.1 8.7 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat RA PF00788.23 CEH14061.1 - 0.097 13.3 0.4 9.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain AMP-binding PF00501.28 CEH14062.1 - 1.2e-75 254.8 0.0 1.6e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 CEH14062.1 - 2.5e-18 66.0 0.5 3.8e-17 62.1 0.5 2.1 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 CEH14062.1 - 8e-07 29.3 0.1 1.7e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CEH14062.1 - 0.031 15.3 0.0 0.1 13.6 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain UQ_con PF00179.26 CEH14064.1 - 2.9e-47 159.9 0.0 3.6e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEH14064.1 - 0.00068 19.3 0.0 0.00094 18.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B CWC25 PF12542.8 CEH14065.1 - 1.3e-22 80.7 0.1 1.3e-22 80.7 0.1 3.5 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 CEH14065.1 - 4.9e-13 49.0 10.1 4.9e-13 49.0 10.1 4.7 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Met_10 PF02475.16 CEH14066.1 - 3.1e-59 200.1 0.0 4.9e-59 199.4 0.0 1.3 1 1 0 1 1 1 1 Met-10+ like-protein UEV PF05743.13 CEH14068.1 - 1.2e-33 115.6 0.1 1.9e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 CEH14068.1 - 2.3e-25 88.3 0.1 4e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 Vps23 core domain RWD PF05773.22 CEH14068.1 - 0.17 12.2 0.2 0.4 11.0 0.0 1.7 2 0 0 2 2 2 0 RWD domain Arf PF00025.21 CEH14069.1 - 1.1e-56 191.0 0.0 1.3e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEH14069.1 - 1.4e-10 41.5 0.0 1.9e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CEH14069.1 - 3.2e-10 39.7 0.0 4.1e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CEH14069.1 - 9.8e-09 34.8 0.1 3.1e-05 23.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CEH14069.1 - 5.3e-07 29.4 0.0 6.7e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CEH14069.1 - 5.7e-07 29.1 0.0 6.9e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEH14069.1 - 1.7e-06 28.1 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH14069.1 - 0.017 14.6 0.0 0.041 13.4 0.0 1.6 1 1 1 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 CEH14069.1 - 0.055 13.0 0.0 8.6 5.8 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CEH14069.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain NOG1 PF06858.14 CEH14069.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) DUF3384 PF11864.8 CEH14070.1 - 1.2e-50 172.8 0.9 4.8e-40 137.9 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 CEH14070.1 - 8.9e-49 165.6 0.0 1.6e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 CEH14070.1 - 3.6e-41 141.5 0.3 2.6e-35 122.2 0.2 3.3 3 0 0 3 3 3 3 Tuberin DOT1 PF08123.13 CEH14073.1 - 1.1e-64 217.7 0.0 1.4e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 CEH14073.1 - 0.045 13.8 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain BTB PF00651.31 CEH14074.1 - 0.004 17.4 0.0 0.0075 16.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain GYF PF02213.16 CEH14075.1 - 5e-05 22.9 0.0 0.00016 21.3 0.0 1.8 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CEH14075.1 - 0.11 12.3 0.9 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 GYF domain 2 Oxysterol_BP PF01237.18 CEH14081.1 - 4.1e-68 229.9 0.5 1.2e-60 205.3 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein NOA36 PF06524.12 CEH14083.1 - 1 8.6 3.1 1.7 7.9 3.1 1.2 1 0 0 1 1 1 0 NOA36 protein PAM2 PF07145.15 CEH14084.1 - 0.011 15.3 0.4 0.034 13.8 0.4 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Macoilin PF09726.9 CEH14084.1 - 0.031 12.9 15.0 0.052 12.1 15.0 1.3 1 0 0 1 1 1 0 Macoilin family MCM3AP_GANP PF16769.5 CEH14084.1 - 1.2 7.3 8.7 1.9 6.6 8.7 1.3 1 0 0 1 1 1 0 MCM3AP domain of GANP Cob_adeno_trans PF01923.18 CEH14084.1 - 1.4 9.0 7.0 0.35 11.0 2.8 1.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Xpo1 PF08389.12 CEH14085.1 - 4.9e-22 78.6 0.1 5.3e-19 68.8 0.0 4.0 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.19 CEH14085.1 - 3.7e-05 23.6 0.6 0.00012 21.9 0.6 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain F-box-like PF12937.7 CEH14087.1 - 1.2e-06 28.3 2.1 1.2e-06 28.3 2.1 3.1 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 CEH14087.1 - 3.9e-05 23.4 2.0 4.8e-05 23.1 0.3 2.1 2 0 0 2 2 2 1 F-box domain DUF2802 PF10975.8 CEH14087.1 - 0.093 12.9 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Phasin PF05597.11 CEH14088.1 - 0.076 13.0 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PHA_synth_III_E PF09712.10 CEH14089.1 - 0.016 14.3 0.5 0.038 13.1 0.5 1.5 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) FliJ PF02050.16 CEH14089.1 - 0.044 14.0 6.2 0.63 10.3 0.9 2.8 2 0 0 2 2 2 0 Flagellar FliJ protein GCR1_C PF12550.8 CEH14089.1 - 0.1 13.0 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes End3 PF12761.7 CEH14089.1 - 0.12 12.6 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Fib_alpha PF08702.10 CEH14089.1 - 0.17 12.0 0.7 6.2 7.0 0.2 3.2 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF5583 PF17821.1 CEH14090.1 - 0.003 17.5 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5583) GCH_III PF05165.12 CEH14090.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase III PINIT PF14324.6 CEH14090.1 - 0.09 13.1 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 PINIT domain MULE PF10551.9 CEH14091.1 - 2.4e-24 85.6 0.2 6.4e-24 84.2 0.2 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 CEH14091.1 - 2.9e-07 29.7 0.0 3.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family OST_IS PF18246.1 CEH14091.1 - 0.055 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Oligosaccharyltransferase Insert domain DUF1990 PF09348.10 CEH14091.1 - 0.065 13.3 0.1 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1990) Vps16_C PF04840.12 CEH14091.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Vps16, C-terminal region Abhydro_lipase PF04083.16 CEH14092.1 - 1.4e-13 50.2 0.0 2.4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CEH14092.1 - 0.00018 21.2 0.2 0.00028 20.6 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DoxX_2 PF13564.6 CEH14092.1 - 0.025 14.7 0.2 6.5 6.9 0.1 2.3 2 0 0 2 2 2 0 DoxX-like family Hydrolase_4 PF12146.8 CEH14092.1 - 0.093 12.0 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 His_biosynth PF00977.21 CEH14093.1 - 2.8e-37 128.4 0.5 3.2e-21 75.9 0.1 2.6 2 1 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.28 CEH14093.1 - 1.2e-17 64.3 0.0 2.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 CEH14093.1 - 4.1e-07 29.8 0.0 8.8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 CEH14093.1 - 0.00021 21.2 0.0 0.0053 16.6 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 CEH14093.1 - 0.085 12.6 0.6 0.76 9.5 0.6 2.2 1 1 0 1 1 1 0 Peptidase C26 Ipi1_N PF12333.8 CEH14094.1 - 5.7e-14 52.5 2.6 2.3e-13 50.6 0.9 2.9 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Alkyl_sulf_dimr PF14863.6 CEH14094.1 - 0.21 12.1 0.7 0.64 10.5 0.1 2.1 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation PhoD PF09423.10 CEH14095.1 - 4.2e-34 118.1 0.2 2.8e-32 112.1 0.2 2.5 1 1 0 1 1 1 1 PhoD-like phosphatase Glyco_hydro_43 PF04616.14 CEH14096.1 - 6.9e-07 28.9 0.1 7.5e-07 28.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Paf67 PF10255.9 CEH14098.1 - 2.1e-166 553.9 0.0 2.9e-166 553.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 CEH14098.1 - 0.0025 17.8 2.3 0.013 15.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEH14098.1 - 0.0065 16.3 0.4 0.089 12.6 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Spt5_N PF11942.8 CEH14098.1 - 0.055 14.4 2.3 9.1 7.3 1.5 2.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ras PF00071.22 CEH14099.1 - 1.4e-60 203.6 0.0 1.6e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH14099.1 - 4.5e-36 123.7 0.0 7.6e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH14099.1 - 4.3e-13 49.1 0.0 5.2e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEH14099.1 - 2.4e-06 27.6 0.0 3.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEH14099.1 - 1.5e-05 24.5 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEH14099.1 - 2.1e-05 24.1 0.0 4.7e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEH14099.1 - 9.4e-05 22.4 1.3 0.32 10.9 0.1 2.5 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 CEH14099.1 - 0.0047 17.3 0.1 0.011 16.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain B12-binding PF02310.19 CEH14099.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain AAA_22 PF13401.6 CEH14099.1 - 0.13 12.5 0.1 1.2 9.4 0.1 2.2 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 CEH14099.1 - 0.15 11.4 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 CEH14099.1 - 0.19 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Septin HGTP_anticodon PF03129.20 CEH14100.1 - 2.9e-19 69.0 0.0 2.5e-08 33.9 0.0 4.1 3 1 2 5 5 5 2 Anticodon binding domain tRNA-synt_2b PF00587.25 CEH14100.1 - 7.3e-17 61.9 0.0 1.3e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 CEH14100.1 - 4e-12 46.2 0.0 7.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.15 CEH14100.1 - 5.8e-08 32.9 0.1 1.3e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain zf-RRN7 PF11781.8 CEH14100.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn-ribbon_8 PF09723.10 CEH14100.1 - 0.19 11.9 0.2 0.43 10.7 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain HMG_box PF00505.19 CEH14101.1 - 1.5e-12 47.7 19.9 8e-07 29.4 2.7 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CEH14101.1 - 1.2e-09 38.6 13.2 9.3e-05 22.9 1.3 2.8 2 0 0 2 2 2 2 HMG-box domain Arabino_trans_C PF14896.6 CEH14101.1 - 0.04 12.9 5.0 0.038 13.0 3.7 1.4 1 1 0 1 1 1 0 EmbC C-terminal domain Deltameth_res PF16020.5 CEH14101.1 - 0.12 12.3 0.5 0.34 10.8 0.5 1.8 1 0 0 1 1 1 0 Deltamethrin resistance DUF3449 PF11931.8 CEH14101.1 - 0.9 9.3 11.8 0.67 9.7 0.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) DUF3856 PF12968.7 CEH14101.1 - 2.5 8.2 7.0 2.6 8.1 0.3 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) RRS1 PF04939.12 CEH14102.1 - 4.1e-47 160.1 2.6 7.3e-47 159.2 2.6 1.4 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) VGLL4 PF15245.6 CEH14102.1 - 1.8 8.6 5.1 1.3 9.1 2.1 1.9 1 1 1 2 2 2 0 Transcription cofactor vestigial-like protein 4 UMP1 PF05348.11 CEH14103.1 - 2.4e-24 85.8 0.2 3.1e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Diphthamide_syn PF01866.17 CEH14104.1 - 1.1e-89 300.9 0.0 2e-50 171.9 0.0 3.8 1 1 1 2 2 2 2 Putative diphthamide synthesis protein BTB PF00651.31 CEH14105.1 - 1e-09 38.6 0.0 0.0016 18.6 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain MFS_1 PF07690.16 CEH14106.1 - 1.3e-29 103.3 32.3 1.6e-29 102.9 32.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH14106.1 - 3.5e-16 59.1 0.6 4.9e-16 58.6 0.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CEH14106.1 - 0.00062 18.3 5.2 0.00082 17.9 5.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 CEH14106.1 - 0.0019 17.5 7.7 0.0032 16.8 7.7 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF536 PF04394.14 CEH14107.1 - 0.04 13.8 1.1 0.11 12.3 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF536 Pkinase PF00069.25 CEH14108.1 - 1.7e-66 224.3 0.0 2.6e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH14108.1 - 3.1e-36 125.0 0.0 1.5e-26 93.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEH14108.1 - 4.1e-05 23.0 0.8 0.00055 19.3 0.8 2.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CEH14108.1 - 0.00078 19.4 2.0 0.0011 18.9 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CEH14108.1 - 0.031 13.3 0.1 0.053 12.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CC2-LZ PF16516.5 CEH14108.1 - 0.27 11.6 2.2 19 5.7 0.8 2.6 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator NT-C2 PF10358.9 CEH14110.1 - 1.5e-06 28.0 0.0 0.00032 20.4 0.0 2.3 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins NAD_binding_5 PF07994.12 CEH14111.1 - 1.5e-145 484.6 0.0 1.9e-145 484.2 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CEH14111.1 - 4.3e-40 136.3 0.1 8.2e-40 135.5 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase COX6A PF02046.15 CEH14114.1 - 1.6e-31 109.1 0.2 2e-31 108.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Cyclin PF08613.11 CEH14115.1 - 9.1e-11 42.4 0.0 2.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEH14115.1 - 4.9e-05 23.1 0.0 8.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ABC_tran PF00005.27 CEH14116.1 - 1e-46 158.9 0.0 1.6e-27 96.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 CEH14116.1 - 2.7e-37 128.9 15.1 1.1e-18 67.9 5.0 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 CEH14116.1 - 2.5e-06 27.1 0.0 0.22 10.9 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEH14116.1 - 1.7e-05 25.3 0.2 0.035 14.5 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain T2SSE PF00437.20 CEH14116.1 - 2.4e-05 23.6 0.0 0.017 14.2 0.0 2.9 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.6 CEH14116.1 - 2.8e-05 24.1 5.9 0.038 13.8 0.0 4.3 3 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEH14116.1 - 4.1e-05 23.2 0.2 0.05 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CEH14116.1 - 0.00017 22.2 0.1 0.12 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CEH14116.1 - 0.0092 16.1 0.6 5.7 7.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.6 CEH14116.1 - 0.0099 16.1 2.9 2.6 8.3 0.0 3.2 3 0 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 CEH14116.1 - 0.013 15.7 0.1 8.6 6.6 0.1 2.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CEH14116.1 - 0.023 14.8 2.3 0.14 12.2 0.2 2.4 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 CEH14116.1 - 0.041 14.1 0.5 2 8.7 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 CEH14116.1 - 0.093 11.5 0.4 6 5.5 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.19 CEH14116.1 - 0.13 11.8 0.6 10 5.7 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 CEH14116.1 - 0.44 10.6 2.0 0.75 9.8 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 CEH14116.1 - 0.47 10.6 3.0 2 8.6 0.0 3.1 3 1 0 3 3 2 0 AAA domain Fructosamin_kin PF03881.14 CEH14117.1 - 5.5e-62 209.6 0.0 6.7e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 CEH14117.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TIM PF00121.18 CEH14118.1 - 3.6e-52 177.2 0.0 4.6e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase DUF829 PF05705.14 CEH14119.1 - 6.8e-24 85.1 0.1 2e-17 63.9 0.1 3.5 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) TERB2 PF15101.6 CEH14119.1 - 3.2 7.7 7.0 11 6.1 7.0 1.9 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Sulfotransfer_4 PF17784.1 CEH14120.1 - 7.1e-26 91.4 0.0 1.6e-25 90.2 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Zn_clus PF00172.18 CEH14123.1 - 0.99 9.6 3.7 2.2 8.5 3.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_22 PF13401.6 CEH14124.1 - 8.7e-15 55.2 0.0 2.5e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CEH14124.1 - 9.8e-09 35.7 0.0 2.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEH14124.1 - 1.8e-05 25.2 2.9 0.0002 21.8 0.2 3.6 2 1 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 CEH14124.1 - 0.00021 20.8 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 CEH14124.1 - 0.00049 20.1 0.0 0.00096 19.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_lid_10 PF17872.1 CEH14124.1 - 0.0034 17.5 0.1 0.0084 16.2 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_14 PF13173.6 CEH14124.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CEH14124.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 CEH14124.1 - 0.025 14.7 0.0 0.1 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain Cdc6_C PF09079.11 CEH14124.1 - 0.083 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain AAA_19 PF13245.6 CEH14124.1 - 0.092 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CEH14124.1 - 0.11 12.3 0.0 2.2 8.1 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 CEH14124.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PIF1 PF05970.14 CEH14124.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 CEH14124.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CEH14124.1 - 0.21 11.5 0.1 3.8 7.4 0.0 2.2 2 0 0 2 2 2 0 NTPase PSP1 PF04468.12 CEH14125.1 - 9.8e-28 96.3 0.6 2.1e-27 95.2 0.6 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DOCK_N PF16172.5 CEH14126.1 - 3.3e-111 371.9 0.0 8e-111 370.6 0.0 1.7 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 CEH14126.1 - 8.7e-77 259.0 0.0 1.2e-76 258.4 0.0 1.2 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 CEH14126.1 - 2.8e-49 167.6 0.0 7e-49 166.3 0.0 1.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins GCP_C_terminal PF04130.13 CEH14127.1 - 1.7e-34 119.7 0.0 2.7e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CEH14127.1 - 1.3e-07 31.6 0.0 2.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal LRR_6 PF13516.6 CEH14128.1 - 0.0024 17.8 8.1 13 6.1 0.0 7.0 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.7 CEH14128.1 - 0.07 13.6 10.6 1.9 9.0 0.0 5.6 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEH14128.1 - 0.074 12.8 3.5 11 5.8 0.3 4.2 3 2 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 CEH14128.1 - 0.11 13.1 5.3 1.4e+02 3.7 0.0 5.9 4 3 1 5 5 5 0 Leucine Rich Repeat DUF4148 PF13663.6 CEH14129.1 - 2.1 8.6 9.2 2.1 8.6 3.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Leu_zip PF15294.6 CEH14129.1 - 2.7 7.5 15.1 4.2 6.8 14.7 1.4 1 1 0 1 1 1 0 Leucine zipper BLOC1_2 PF10046.9 CEH14129.1 - 2.7 8.4 6.4 1.6 9.0 1.5 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4509 PF14970.6 CEH14129.1 - 4.3 7.2 9.3 1.3 8.9 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4509) DUF4200 PF13863.6 CEH14129.1 - 7.4 7.0 24.3 0.094 13.1 6.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FAD_binding_3 PF01494.19 CEH14130.1 - 2.7e-08 33.5 0.5 1.2e-05 24.8 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CEH14130.1 - 1e-07 31.9 0.7 1e-07 31.9 0.7 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEH14130.1 - 3.4e-06 27.2 0.1 1.1e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEH14130.1 - 0.00078 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CEH14130.1 - 0.0015 17.7 0.3 0.12 11.4 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CEH14130.1 - 0.003 16.7 0.1 0.0049 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 CEH14130.1 - 0.008 15.1 0.1 0.013 14.3 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 CEH14130.1 - 0.0097 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEH14130.1 - 0.024 15.2 0.0 0.05 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 CEH14130.1 - 0.039 13.0 0.0 0.058 12.4 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase ApbA PF02558.16 CEH14130.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 CEH14130.1 - 0.077 11.7 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 CEH14130.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF383 PF04063.14 CEH14130.1 - 0.21 11.2 0.0 0.51 10.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF383) G-patch PF01585.23 CEH14131.1 - 0.00032 20.5 3.6 0.00032 20.5 3.6 2.3 2 0 0 2 2 2 1 G-patch domain HalOD2 PF18547.1 CEH14131.1 - 0.022 14.7 0.6 0.064 13.2 0.6 1.8 1 0 0 1 1 1 0 Halobacterial output domain 2 bZIP_1 PF00170.21 CEH14132.1 - 1.5e-05 25.0 6.2 1.5e-05 25.0 6.2 2.3 2 0 0 2 2 2 1 bZIP transcription factor Myb_DNA-binding PF00249.31 CEH14136.1 - 8.8e-36 121.9 3.7 3.5e-17 62.3 1.5 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH14136.1 - 6.1e-23 80.8 3.3 5.5e-16 58.6 0.0 4.2 2 1 2 4 4 4 3 Myb-like DNA-binding domain SLIDE PF09111.10 CEH14136.1 - 0.00039 20.4 0.0 1.4 8.9 0.0 2.8 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 CEH14136.1 - 0.0024 17.9 1.6 0.16 12.1 1.3 2.7 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 CEH14136.1 - 0.12 12.7 0.7 7.5 7.0 0.1 3.0 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Spore_III_AB PF09548.10 CEH14136.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 CEH14136.1 - 0.17 12.3 1.8 3.6 8.0 0.2 2.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain UBN_AB PF14075.6 CEH14138.1 - 1.9e-32 112.7 0.0 2.7e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Ubinuclein conserved middle domain HUN PF08729.10 CEH14138.1 - 5.9e-08 32.6 0.2 1.5e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain CAF1C_H4-bd PF12265.8 CEH14139.1 - 4.7e-32 110.1 0.1 1.3e-31 108.6 0.1 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CEH14139.1 - 2.7e-23 81.8 6.6 0.00011 22.9 0.3 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH14139.1 - 1.3e-06 28.6 2.2 0.044 14.1 0.0 5.3 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEH14139.1 - 0.0014 18.5 0.2 0.0097 15.8 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PA_decarbox PF05870.11 CEH14140.1 - 1.4e-20 73.5 0.1 1.9e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF PF10703.9 CEH14140.1 - 0.036 14.0 0.0 0.19 11.7 0.0 2.0 1 1 0 1 1 1 0 MoaF N-terminal domain Rad60-SLD_2 PF13881.6 CEH14141.1 - 7e-14 51.9 0.0 1.6e-13 50.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Erf4 PF10256.9 CEH14142.1 - 5.1e-29 100.7 0.0 6.1e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Ras PF00071.22 CEH14143.1 - 1.1e-63 213.7 0.1 1.3e-63 213.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH14143.1 - 2.9e-34 117.9 0.1 4.6e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH14143.1 - 5.1e-13 48.8 0.1 6.3e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEH14143.1 - 0.0001 22.3 0.0 0.00024 21.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEH14143.1 - 0.00011 21.8 0.2 0.00026 20.6 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEH14143.1 - 0.00013 21.9 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CEH14143.1 - 0.00032 20.1 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CEH14143.1 - 0.012 15.1 0.0 0.66 9.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 CEH14143.1 - 0.015 15.7 0.0 0.024 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CEH14143.1 - 0.044 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 CEH14143.1 - 0.047 13.1 0.0 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 CEH14143.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MCM PF00493.23 CEH14143.1 - 0.095 11.8 0.0 0.33 10.0 0.0 1.8 2 1 0 2 2 2 0 MCM P-loop domain ABC_tran PF00005.27 CEH14143.1 - 0.11 13.0 0.2 0.61 10.6 0.2 2.0 1 1 0 1 1 1 0 ABC transporter LSM PF01423.22 CEH14146.1 - 1.2e-10 41.0 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain ABC_membrane PF00664.23 CEH14147.1 - 6.2e-45 154.0 12.5 8.1e-25 88.0 4.2 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEH14147.1 - 5.6e-43 146.8 0.0 7.5e-25 88.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEH14147.1 - 1.6e-11 44.1 0.2 0.00014 21.4 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEH14147.1 - 4.5e-07 29.5 0.1 0.012 15.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CEH14147.1 - 6e-07 29.6 1.5 0.29 10.9 0.1 3.4 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 CEH14147.1 - 4.4e-06 26.0 0.0 0.066 12.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 CEH14147.1 - 2.2e-05 24.5 0.0 0.0081 16.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 CEH14147.1 - 3.7e-05 24.3 0.1 0.51 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEH14147.1 - 6.3e-05 23.3 0.0 0.37 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 CEH14147.1 - 7.5e-05 22.4 1.7 0.033 13.8 0.2 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CEH14147.1 - 0.00014 22.3 11.7 0.024 15.0 6.2 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CEH14147.1 - 0.00049 19.7 0.0 0.96 9.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CEH14147.1 - 0.001 18.8 0.0 1.2 8.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CEH14147.1 - 0.0027 17.6 0.1 3.3 7.6 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase TrwB_AAD_bind PF10412.9 CEH14147.1 - 0.0029 16.6 0.0 0.55 9.1 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 CEH14147.1 - 0.0045 16.8 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.17 CEH14147.1 - 0.0046 16.8 0.1 2.3 7.9 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 CEH14147.1 - 0.0064 16.2 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CEH14147.1 - 0.0096 16.0 0.9 6.1 6.9 0.1 2.9 3 0 0 3 3 3 0 Dynamin family MobB PF03205.14 CEH14147.1 - 0.0098 15.8 0.7 2.4 8.1 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 CEH14147.1 - 0.011 15.8 0.0 0.053 13.6 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 CEH14147.1 - 0.011 15.8 0.0 3.1 8.0 0.1 3.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CEH14147.1 - 0.015 14.3 0.1 0.034 13.1 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 CEH14147.1 - 0.02 14.4 0.1 2 7.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CEH14147.1 - 0.02 14.8 0.3 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 CEH14147.1 - 0.021 15.4 0.1 6 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CEH14147.1 - 0.026 13.9 0.2 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 CEH14147.1 - 0.027 14.2 0.1 7.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CEH14147.1 - 0.03 14.7 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEH14147.1 - 0.046 14.2 0.3 5.7 7.4 0.1 3.5 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CEH14147.1 - 0.067 13.1 0.5 6.3 6.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 CEH14147.1 - 0.11 11.8 0.2 4 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.12 CEH14147.1 - 0.13 11.7 0.1 6.1 6.2 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 CEH14147.1 - 0.46 10.5 2.6 20 5.2 0.0 3.7 5 0 0 5 5 3 0 AAA domain (dynein-related subfamily) UPA_2 PF17809.1 CEH14148.1 - 0.027 14.3 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 UPA domain RabGAP-TBC PF00566.18 CEH14149.1 - 5.7e-47 160.1 0.3 2.5e-41 141.7 0.1 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain TcpS PF17456.2 CEH14149.1 - 0.16 12.0 4.0 11 6.0 1.4 2.4 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S DivIVA PF05103.13 CEH14149.1 - 1.1 9.4 9.2 0.15 12.1 3.5 2.2 2 0 0 2 2 2 0 DivIVA protein DUF4315 PF14193.6 CEH14149.1 - 5.4 7.1 8.4 20 5.3 2.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4315) ArsA_ATPase PF02374.15 CEH14152.1 - 1e-111 373.0 4.0 3e-72 243.4 0.5 2.0 1 1 1 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 CEH14152.1 - 2.5e-12 47.1 0.1 1.5e-11 44.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 CEH14152.1 - 6.7e-12 45.6 0.0 1.6e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CEH14152.1 - 3.5e-05 23.4 0.1 9.3e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 CEH14152.1 - 3.6e-05 23.4 0.0 9.2e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 CEH14152.1 - 5.1e-05 22.8 4.1 0.00017 21.1 1.1 2.7 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 CEH14152.1 - 0.00013 21.6 0.0 0.00068 19.3 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PhoH PF02562.16 CEH14152.1 - 0.0057 16.1 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.6 CEH14152.1 - 0.029 13.9 0.9 0.33 10.5 0.5 2.4 2 1 1 3 3 3 0 AAA domain VirC1 PF07015.11 CEH14152.1 - 0.083 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein AAA_24 PF13479.6 CEH14152.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CEH14152.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MipZ PF09140.11 CEH14152.1 - 0.18 11.1 0.0 0.35 10.1 0.0 1.5 2 0 0 2 2 2 0 ATPase MipZ SWIRM PF04433.17 CEH14153.1 - 3e-29 101.2 0.0 6.7e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 CEH14153.1 - 4.8e-29 100.1 7.1 4.8e-29 100.1 7.1 2.0 2 0 0 2 2 2 1 SWIRM-associated region 1 SWIRM-assoc_2 PF16496.5 CEH14153.1 - 2.8e-22 79.2 0.4 6.6e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal Myb_DNA-binding PF00249.31 CEH14153.1 - 3.6e-10 39.9 0.0 6.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH14153.1 - 1.3e-06 28.5 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 CEH14153.1 - 0.0052 16.6 1.9 0.011 15.5 1.9 1.5 1 1 0 1 1 1 1 Zinc finger, ZZ type Cellulase PF00150.18 CEH14154.1 - 1.1e-11 44.8 3.2 1.5e-11 44.2 3.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RhoGAP PF00620.27 CEH14155.1 - 2.6e-23 82.6 0.0 4.3e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 CEH14155.1 - 1.1e-16 61.2 0.0 3e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 CEH14155.1 - 2.3e-08 34.0 4.8 0.0005 20.1 4.3 2.5 2 0 0 2 2 2 2 WW domain MT-A70 PF05063.14 CEH14156.1 - 2.4e-35 122.0 0.0 4.9e-34 117.7 0.0 2.1 1 1 0 1 1 1 1 MT-A70 Septin PF00735.18 CEH14157.1 - 2.1e-108 361.9 0.8 2.2e-108 361.8 0.0 1.3 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CEH14157.1 - 8.2e-08 32.3 0.0 2.1e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEH14157.1 - 0.00022 21.2 3.9 0.0063 16.4 0.6 3.2 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 CEH14157.1 - 0.00037 20.6 4.4 0.043 13.9 0.1 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 CEH14157.1 - 0.00055 19.5 0.5 0.027 14.0 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CEH14157.1 - 0.0033 16.8 0.0 0.0068 15.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.18 CEH14157.1 - 0.0047 16.3 0.2 0.0099 15.3 0.2 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 CEH14157.1 - 0.0067 16.7 0.9 0.015 15.6 0.0 2.1 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEH14157.1 - 0.0069 16.6 0.1 0.022 15.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH14157.1 - 0.012 15.9 0.2 0.18 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CEH14157.1 - 0.012 16.0 0.9 0.024 15.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 CEH14157.1 - 0.016 15.5 3.1 0.24 11.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain IIGP PF05049.13 CEH14157.1 - 0.017 14.2 0.2 0.044 12.8 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 CEH14157.1 - 0.018 15.3 0.0 0.05 13.8 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CEH14157.1 - 0.028 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CEH14157.1 - 0.033 14.7 1.7 1.4 9.4 0.0 3.2 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 CEH14157.1 - 0.04 14.4 0.1 0.14 12.6 0.0 2.0 2 1 0 2 2 2 0 ABC transporter Gtr1_RagA PF04670.12 CEH14157.1 - 0.052 12.9 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 CEH14157.1 - 0.075 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 CEH14157.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_23 PF13476.6 CEH14157.1 - 0.16 12.5 12.7 5.1 7.6 12.7 2.1 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 CEH14157.1 - 0.19 11.3 0.4 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 Ras family ATP_bind_1 PF03029.17 CEH14157.1 - 0.23 11.2 1.2 1.6 8.4 0.4 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 CEH14157.1 - 1.3 9.1 5.4 1.4 9.0 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Pkinase PF00069.25 CEH14158.1 - 5.4e-56 189.9 0.0 4.4e-55 186.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH14158.1 - 1.2e-26 93.5 0.0 8.1e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CEH14158.1 - 0.0023 17.9 0.2 0.34 10.8 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEH14158.1 - 0.011 15.1 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CEH14158.1 - 0.02 14.2 0.1 0.061 12.7 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEH14158.1 - 0.034 13.1 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RAMA PF18755.1 CEH14158.1 - 0.11 12.9 0.3 0.31 11.5 0.3 1.7 1 0 0 1 1 1 0 Restriction Enzyme Adenine Methylase Associated WD40 PF00400.32 CEH14159.1 - 0.0011 19.7 10.9 0.49 11.3 0.2 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 CEH14159.1 - 0.041 14.4 1.7 15 6.2 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain BEX PF04538.12 CEH14159.1 - 2.4 8.7 11.4 7.5 7.2 4.9 3.1 3 0 0 3 3 3 0 Brain expressed X-linked like family TLP-20 PF06088.11 CEH14159.1 - 2.8 7.8 6.2 5.2 6.9 2.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) YL1 PF05764.13 CEH14159.1 - 3.8 7.5 17.1 0.34 11.0 7.4 2.8 3 0 0 3 3 3 0 YL1 nuclear protein DUF4611 PF15387.6 CEH14159.1 - 8.1 6.7 15.3 4.1 7.7 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SUR7 PF06687.12 CEH14160.1 - 9.9e-16 58.0 6.7 1.4e-15 57.5 6.7 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 CEH14160.1 - 0.0021 17.9 2.5 0.0027 17.5 1.9 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Phage_holin_3_6 PF07332.11 CEH14160.1 - 0.022 14.8 4.0 0.022 14.8 4.0 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Wzy_C PF04932.15 CEH14160.1 - 0.029 14.0 0.5 0.076 12.6 0.3 1.9 2 0 0 2 2 2 0 O-Antigen ligase DUF3169 PF11368.8 CEH14160.1 - 0.06 12.8 1.4 0.091 12.3 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) DUF2070 PF09843.9 CEH14160.1 - 0.074 11.3 7.5 0.12 10.7 7.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) BRI3BP PF14965.6 CEH14160.1 - 0.098 12.2 3.8 0.15 11.5 3.8 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DUF2254 PF10011.9 CEH14160.1 - 1 8.1 5.0 1.9 7.2 5.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF2628 PF10947.8 CEH14160.1 - 4.5 7.7 10.5 4.1 7.8 7.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) adh_short PF00106.25 CEH14161.1 - 7.3e-05 22.3 0.0 0.49 9.8 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase AAA PF00004.29 CEH14162.1 - 3e-24 85.9 0.0 8.8e-24 84.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 CEH14162.1 - 3.1e-05 24.0 0.4 0.0003 20.8 0.4 2.1 1 1 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 CEH14162.1 - 3.7e-05 24.2 2.4 5.2e-05 23.7 0.6 2.4 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 CEH14162.1 - 8.1e-05 22.6 0.0 0.00019 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEH14162.1 - 0.00015 22.1 0.2 0.00087 19.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CEH14162.1 - 0.0007 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CEH14162.1 - 0.0014 19.1 0.0 0.0027 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEH14162.1 - 0.0027 17.4 0.1 0.011 15.5 0.1 2.0 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 CEH14162.1 - 0.0031 17.1 0.1 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEH14162.1 - 0.0051 16.4 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 CEH14162.1 - 0.0052 16.0 0.0 0.0085 15.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 CEH14162.1 - 0.0055 16.6 0.4 1.9 8.4 0.1 2.5 1 1 1 2 2 2 1 NACHT domain AAA_24 PF13479.6 CEH14162.1 - 0.0075 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CEH14162.1 - 0.012 15.9 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 CEH14162.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CEH14162.1 - 0.015 14.6 0.0 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.6 CEH14162.1 - 0.032 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 CEH14162.1 - 0.042 14.2 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 CEH14162.1 - 0.042 14.1 0.3 0.19 11.9 0.2 2.2 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 CEH14162.1 - 0.052 13.7 0.3 0.11 12.6 0.3 1.7 1 1 0 1 1 1 0 AAA domain PTPRCAP PF15713.5 CEH14162.1 - 0.053 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Mg_chelatase PF01078.21 CEH14162.1 - 0.055 12.9 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 CEH14162.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 CEH14162.1 - 0.096 12.4 0.2 0.23 11.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.9 CEH14162.1 - 0.1 11.8 0.4 1.3 8.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 CEH14162.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 CEH14162.1 - 0.16 12.4 0.0 0.43 11.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter TIP120 PF08623.10 CEH14163.1 - 2e-53 180.6 1.3 4.3e-49 166.5 0.0 4.9 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) zf-DNL PF05180.12 CEH14163.1 - 7.8e-27 93.0 0.1 1.6e-26 92.0 0.1 1.5 1 0 0 1 1 1 1 DNL zinc finger HEAT_2 PF13646.6 CEH14163.1 - 1.1e-13 51.4 38.6 0.0078 16.6 0.7 10.7 9 2 1 10 10 10 6 HEAT repeats HEAT_EZ PF13513.6 CEH14163.1 - 8.1e-11 42.2 28.3 0.053 14.0 0.7 10.6 9 1 1 10 10 10 4 HEAT-like repeat HEAT PF02985.22 CEH14163.1 - 2.5e-10 39.7 28.2 0.35 11.2 0.0 12.4 13 0 0 13 13 13 3 HEAT repeat Cnd1 PF12717.7 CEH14163.1 - 6.4e-10 39.3 2.2 0.0077 16.3 0.0 4.5 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CEH14163.1 - 1.4e-08 33.8 12.5 0.058 11.9 0.1 5.3 4 1 1 5 5 5 3 Adaptin N terminal region RTP1_C1 PF10363.9 CEH14163.1 - 0.00096 19.3 4.8 13 6.0 0.3 6.3 5 2 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 CEH14163.1 - 0.008 16.2 7.4 1.6 8.9 0.2 5.1 5 0 0 5 5 4 2 Armadillo/beta-catenin-like repeat MMU163 PF17119.5 CEH14163.1 - 0.032 13.4 0.0 5.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis MMS19_C PF12460.8 CEH14163.1 - 0.094 11.8 14.1 0.59 9.2 0.6 4.7 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal API5 PF05918.11 CEH14163.1 - 0.26 10.0 5.0 0.31 9.8 0.5 3.0 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) DUF2664 PF10867.8 CEH14163.1 - 0.79 10.2 3.5 36 4.9 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) DUF3731 PF12531.8 CEH14163.1 - 7.6 6.3 8.4 9.8 5.9 0.0 4.3 4 1 1 5 5 5 0 DNA-K related protein DUF3336 PF11815.8 CEH14164.1 - 1e-43 148.3 0.5 1.6e-43 147.7 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CEH14164.1 - 1.5e-17 64.5 0.0 3.5e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Ferritin_2 PF13668.6 CEH14165.1 - 8.2e-37 126.4 4.1 1.4e-36 125.7 4.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain Vps8 PF12816.7 CEH14166.1 - 2.4e-68 229.6 0.0 4e-68 228.8 0.0 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 ANAPC4_WD40 PF12894.7 CEH14166.1 - 0.0052 17.1 0.0 0.47 10.8 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 CEH14166.1 - 0.011 15.7 0.3 3.2 7.6 0.0 3.2 3 0 0 3 3 3 0 Region in Clathrin and VPS WD40 PF00400.32 CEH14166.1 - 0.039 14.8 2.8 0.082 13.8 0.2 3.1 2 1 1 3 3 3 0 WD domain, G-beta repeat TB2_DP1_HVA22 PF03134.19 CEH14167.1 - 5.1e-28 96.8 4.1 5.1e-28 96.8 4.1 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family zf-HC5HC2H_2 PF13832.6 CEH14168.1 - 1.7e-17 63.6 1.9 1.7e-17 63.6 1.9 4.2 4 0 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CEH14168.1 - 2.4e-14 53.3 2.8 2.4e-14 53.3 2.8 4.4 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 CEH14168.1 - 1.1e-11 44.4 25.2 2.3e-09 37.0 6.3 5.4 6 0 0 6 6 6 2 PHD-finger BAH PF01426.18 CEH14168.1 - 1.3e-07 31.5 0.0 2.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.6 CEH14168.1 - 1.7e-05 24.2 4.1 1.7e-05 24.2 4.1 5.5 8 0 0 8 8 8 2 PHD-finger GATA PF00320.27 CEH14168.1 - 0.0003 20.3 5.1 0.0003 20.3 5.1 3.4 3 0 0 3 3 3 1 GATA zinc finger DUF4666 PF15697.5 CEH14168.1 - 0.091 13.5 2.8 1.9 9.2 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) ELM2 PF01448.24 CEH14168.1 - 0.1 13.4 0.1 0.64 10.8 0.1 2.3 1 1 0 1 1 1 0 ELM2 domain Myb_DNA-bind_7 PF15963.5 CEH14168.1 - 0.21 11.5 0.5 0.47 10.4 0.5 1.5 1 0 0 1 1 1 0 Myb DNA-binding like C1_2 PF03107.16 CEH14168.1 - 2 8.8 32.6 0.91 9.9 2.6 6.0 6 0 0 6 6 6 0 C1 domain Oxysterol_BP PF01237.18 CEH14170.1 - 2.2e-89 299.9 2.1 1.4e-79 267.7 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Oxysterol_BP PF01237.18 CEH14171.1 - 8.3e-116 386.9 0.0 1.5e-115 386.0 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 CEH14171.1 - 1.5e-16 60.4 1.9 6.4e-16 58.4 0.1 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CEH14171.1 - 2.6e-05 24.6 0.0 8e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 PH domain MFS_1 PF07690.16 CEH14172.1 - 2.9e-26 92.2 43.1 7.5e-23 81.0 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH14172.1 - 1.3e-17 63.8 18.1 1.8e-13 50.2 5.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEH14173.1 - 1.4e-48 165.7 30.1 4e-43 147.7 19.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH14173.1 - 4.8e-13 48.8 8.0 4.8e-13 48.8 8.0 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CEH14173.1 - 7.2e-09 34.6 0.6 1.3e-08 33.8 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 CEH14173.1 - 2.4 6.9 11.3 0.37 9.6 1.9 3.1 2 2 1 3 3 3 0 MFS_1 like family zf-UBR PF02207.20 CEH14174.1 - 2.7e-19 69.1 14.0 2.7e-19 69.1 14.0 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CEH14174.1 - 2.4e-11 43.2 0.2 1.3e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Astro_capsid_p PF12226.8 CEH14174.1 - 0.52 9.4 1.8 0.98 8.5 1.8 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-met2 PF12907.7 CEH14175.1 - 2.8e-12 46.5 1.1 4e-12 46.1 1.1 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 CEH14175.1 - 1.7e-09 38.3 8.2 1.7e-09 38.3 8.2 1.5 2 0 0 2 2 2 1 4F5 protein family HLH PF00010.26 CEH14176.1 - 3.6e-05 23.6 0.0 0.0001 22.2 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Lactamase_B_2 PF12706.7 CEH14177.1 - 2.9e-22 79.2 0.0 1.6e-21 76.8 0.0 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEH14177.1 - 6.3e-06 26.2 0.0 3.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CEH14177.1 - 0.0053 16.8 0.6 0.0053 16.8 0.6 2.1 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily TPT PF03151.16 CEH14178.1 - 3.4e-22 79.1 18.0 4.4e-22 78.8 18.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CEH14178.1 - 3.2e-09 37.1 29.5 5.9e-05 23.3 9.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CEH14178.1 - 0.88 8.7 21.4 1.1 8.4 18.6 2.0 1 1 1 2 2 2 0 UAA transporter family DUF89 PF01937.19 CEH14179.1 - 6.2e-101 337.9 0.0 7.5e-101 337.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF866 PF05907.13 CEH14180.1 - 2.7e-45 154.0 0.1 3.1e-45 153.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) NTF2 PF02136.20 CEH14180.1 - 0.076 13.6 0.1 0.11 13.1 0.1 1.3 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Aldo_ket_red PF00248.21 CEH14181.1 - 1.6e-49 168.7 0.0 8.9e-48 163.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family AAR2 PF05282.11 CEH14182.1 - 2.1e-39 135.9 0.1 2.8e-39 135.5 0.1 1.1 1 0 0 1 1 1 1 AAR2 protein SF3A2 PF16835.5 CEH14183.1 - 2.6e-28 98.2 0.0 4.3e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CEH14183.1 - 9.1e-07 29.1 0.7 2.1e-06 27.9 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 CEH14183.1 - 0.059 13.3 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 CEH14183.1 - 0.1 12.1 1.0 0.19 11.3 1.0 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like FAM72 PF14976.6 CEH14184.1 - 2.7e-16 60.0 0.7 6.3e-16 58.8 0.7 1.6 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 CEH14184.1 - 0.03 14.5 5.0 0.39 11.0 1.8 2.6 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cullin PF00888.22 CEH14187.1 - 1.2e-162 542.7 0.0 1.5e-162 542.4 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CEH14187.1 - 2.3e-23 82.0 1.2 5.5e-23 80.8 1.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain UPF0220 PF05255.11 CEH14188.1 - 6.3e-48 162.5 0.1 7.5e-48 162.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Ank_2 PF12796.7 CEH14189.1 - 1.4e-12 48.0 0.0 2.7e-11 43.9 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CEH14189.1 - 7.8e-12 45.1 0.0 0.00031 21.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CEH14189.1 - 2.1e-11 43.0 0.0 0.00076 19.8 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CEH14189.1 - 9.7e-11 41.7 0.0 5.5e-09 36.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEH14189.1 - 8.7e-10 39.0 0.0 0.00069 20.1 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Cytochrom_B_N_2 PF13631.6 CEH14190.1 - 0.061 13.3 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Tox-HNH-HHH PF15637.6 CEH14190.1 - 0.2 11.8 0.0 8.5 6.6 0.0 2.4 2 1 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif VHS PF00790.19 CEH14191.1 - 2.5e-27 95.4 0.5 5.1e-27 94.4 0.5 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 CEH14191.1 - 4.6e-16 58.2 0.0 9.3e-16 57.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEH14191.1 - 2e-15 56.3 0.1 4.2e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEH14191.1 - 2.1e-11 43.3 0.0 4.7e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 CEH14191.1 - 1.4e-08 34.9 0.5 3.9e-08 33.5 0.5 1.8 1 0 0 1 1 1 1 GAT domain DUF3361 PF11841.8 CEH14191.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) UIM PF02809.20 CEH14191.1 - 1.8 8.6 7.3 0.087 12.8 1.0 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif PDCD2_C PF04194.13 CEH14192.1 - 6.9e-32 110.9 5.4 9.6e-32 110.4 0.0 3.5 4 1 0 4 4 4 1 Programmed cell death protein 2, C-terminal putative domain Cwf_Cwc_15 PF04889.12 CEH14192.1 - 0.15 11.8 8.0 0.036 13.8 3.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pterin_bind PF00809.22 CEH14193.1 - 8.3e-80 268.0 2.9 1.1e-78 264.3 2.9 2.3 1 1 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 CEH14193.1 - 6.5e-44 149.0 1.2 9.9e-23 80.8 0.9 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 CEH14193.1 - 9.5e-33 113.1 0.0 2e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) EF-hand_1 PF00036.32 CEH14194.1 - 6.3e-42 138.0 11.9 5.5e-10 38.1 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEH14194.1 - 9.3e-36 122.1 2.0 3.3e-18 65.9 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEH14194.1 - 7.3e-32 106.6 6.4 1.3e-09 37.2 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CEH14194.1 - 3.5e-31 106.8 10.5 2.9e-14 52.7 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CEH14194.1 - 3.4e-26 89.5 8.4 9.6e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CEH14194.1 - 3.6e-16 59.2 0.1 2e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CEH14194.1 - 2.3e-09 37.1 0.9 5.9e-05 23.0 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CEH14194.1 - 1.2e-08 35.2 0.0 0.00098 19.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 CEH14194.1 - 1.3e-06 28.3 0.1 0.039 14.0 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 CEH14194.1 - 4.9e-05 23.4 4.9 0.0085 16.3 0.5 3.1 1 1 1 2 2 2 2 Dockerin type I domain EF-hand_11 PF08976.11 CEH14194.1 - 5.5e-05 24.0 0.0 0.019 15.8 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 CEH14194.1 - 6.3e-05 23.0 0.4 0.00026 21.0 0.1 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 CEH14194.1 - 0.00042 20.0 2.0 0.00048 19.8 2.0 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 CEH14194.1 - 0.001 19.0 1.3 0.64 9.9 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF5580 PF17743.1 CEH14194.1 - 0.0027 16.3 0.0 0.0027 16.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Poly_export PF02563.16 CEH14194.1 - 0.0028 17.8 0.1 0.4 10.9 0.0 3.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein SapB_1 PF05184.15 CEH14194.1 - 0.0037 17.2 0.7 18 5.5 0.0 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 1 RNA_pol_Rpb4 PF03874.16 CEH14194.1 - 0.0037 17.6 0.4 1.6 9.1 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 MotA_activ PF09114.10 CEH14194.1 - 0.0063 16.6 0.5 0.11 12.7 0.1 2.3 1 1 0 2 2 2 1 Transcription factor MotA, activation domain DUF4497 PF14924.6 CEH14194.1 - 0.0065 16.9 0.0 1 9.9 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) dCache_2 PF08269.11 CEH14194.1 - 0.01 15.0 0.2 0.48 9.6 0.1 2.3 1 1 1 2 2 2 0 Cache domain TerB PF05099.13 CEH14194.1 - 0.025 14.5 0.2 1.2 9.1 0.0 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB EF-hand_14 PF17959.1 CEH14194.1 - 0.035 14.4 0.1 10 6.5 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 CEH14194.1 - 0.036 13.9 0.8 0.97 9.3 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF1811 PF08838.10 CEH14194.1 - 0.038 14.2 0.0 14 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) RuvA_C PF07499.13 CEH14194.1 - 0.059 13.8 0.1 6.1 7.4 0.0 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain Fe_hyd_lg_C PF02906.14 CEH14194.1 - 0.065 12.9 0.2 0.12 12.0 0.2 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DEAD PF00270.29 CEH14195.1 - 6.3e-42 143.3 0.0 1.3e-41 142.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH14195.1 - 3.4e-30 104.7 0.0 1.9e-28 99.0 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CEH14195.1 - 0.013 14.8 0.0 0.013 14.8 0.0 3.9 2 1 2 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit DAGAT PF03982.13 CEH14195.1 - 0.035 13.0 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase NTP_transf_9 PF04248.12 CEH14196.1 - 1.5e-24 85.7 1.1 7.9e-24 83.4 0.3 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF427) PIN_11 PF18479.1 CEH14196.1 - 0.099 12.8 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 PIN like domain Ras PF00071.22 CEH14197.1 - 1.8e-29 102.5 0.0 9.6e-27 93.6 0.0 3.0 3 0 0 3 3 3 1 Ras family Roc PF08477.13 CEH14197.1 - 1.1e-23 83.7 0.0 2.9e-23 82.4 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH14197.1 - 1.3e-05 24.7 0.0 3.6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEH14197.1 - 0.035 14.2 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 CEH14197.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CEH14197.1 - 0.11 12.9 0.2 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Transcrip_act PF04949.13 CEH14198.1 - 0.051 13.5 1.8 0.096 12.6 1.8 1.4 1 0 0 1 1 1 0 Transcriptional activator L51_S25_CI-B8 PF05047.16 CEH14198.1 - 0.08 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain UQ_con PF00179.26 CEH14199.1 - 4.5e-28 97.6 0.0 5.6e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEH14199.1 - 0.0024 17.5 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CEH14199.1 - 0.0055 16.6 0.0 0.0079 16.1 0.0 1.2 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.11 CEH14199.1 - 0.015 15.0 0.0 0.023 14.3 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 DNA_ligase_A_C PF04679.15 CEH14199.1 - 0.028 15.0 0.0 0.093 13.3 0.0 1.7 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region RWD PF05773.22 CEH14199.1 - 0.14 12.4 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 CEH14200.1 - 2.3e-35 120.0 12.5 7.5e-07 29.8 0.4 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 CEH14200.1 - 0.00024 19.9 0.5 3.2 6.3 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PQQ_3 PF13570.6 CEH14200.1 - 0.034 14.6 1.7 0.11 13.0 0.1 2.8 4 0 0 4 4 4 0 PQQ-like domain MSP PF01716.18 CEH14200.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide Nucleoporin_N PF08801.11 CEH14200.1 - 0.23 10.2 0.2 16 4.1 0.0 3.1 2 1 1 4 4 4 0 Nup133 N terminal like zf-RING_5 PF14634.6 CEH14201.1 - 7.6e-06 25.8 4.4 1.5e-05 24.8 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEH14201.1 - 0.0002 21.3 2.0 0.00037 20.5 2.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger FYVE PF01363.21 CEH14201.1 - 0.00028 20.9 4.8 0.00071 19.7 4.8 1.7 1 1 0 1 1 1 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 CEH14201.1 - 0.0043 16.9 1.4 0.0043 16.9 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEH14201.1 - 0.0089 16.4 7.8 0.022 15.1 7.8 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEH14201.1 - 0.012 15.5 6.3 0.042 13.7 6.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEH14201.1 - 0.013 15.3 6.9 0.015 15.1 2.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 CEH14201.1 - 0.027 14.8 2.6 3.4 8.0 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon zf-AD PF07776.15 CEH14201.1 - 0.068 13.4 0.8 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-C3HC4_4 PF15227.6 CEH14201.1 - 0.082 13.1 8.9 5.7 7.2 10.3 2.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zinc_ribbon_5 PF13719.6 CEH14201.1 - 0.23 11.2 0.2 0.23 11.2 0.2 2.7 2 1 0 2 2 1 0 zinc-ribbon domain Rtf2 PF04641.12 CEH14201.1 - 0.33 10.3 9.0 0.044 13.1 0.5 2.3 1 1 0 2 2 2 0 Rtf2 RING-finger DZR PF12773.7 CEH14201.1 - 0.4 10.7 7.3 13 6.0 7.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon Rpr2 PF04032.16 CEH14201.1 - 0.66 10.3 4.8 5.6 7.3 3.6 2.5 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain IBR PF01485.21 CEH14201.1 - 1.3 9.3 4.8 30 4.9 4.9 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 CEH14201.1 - 1.5 8.8 11.4 17 5.4 6.7 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zinc-ribbons_6 PF07191.12 CEH14201.1 - 2.2 8.3 6.4 99 3.0 6.5 2.4 1 1 0 1 1 1 0 zinc-ribbons UPF0547 PF10571.9 CEH14201.1 - 5.2 7.2 11.1 0.93 9.6 1.0 3.1 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 ING PF12998.7 CEH14203.1 - 7.4e-16 58.6 0.1 1.6e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CEH14203.1 - 0.00013 21.7 7.3 0.00022 21.1 7.3 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CEH14203.1 - 0.21 11.8 1.2 0.44 10.8 1.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF5320 PF17253.2 CEH14203.1 - 3 9.0 11.6 6.6 7.9 9.6 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) PrmA PF06325.13 CEH14204.1 - 9.6e-13 48.2 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CEH14204.1 - 5.5e-10 39.8 0.0 2.2e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH14204.1 - 2.2e-09 37.3 0.0 4.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH14204.1 - 2e-07 31.6 0.0 6.7e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH14204.1 - 1.2e-05 25.2 0.0 2.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEH14204.1 - 3.2e-05 23.5 0.1 6e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 CEH14204.1 - 6.2e-05 24.0 0.0 0.00029 21.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CEH14204.1 - 9.4e-05 22.4 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEH14204.1 - 0.00052 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 CEH14204.1 - 0.0018 18.0 0.1 0.003 17.2 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 CEH14204.1 - 0.0021 17.8 0.1 0.0033 17.2 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CEH14204.1 - 0.0029 17.3 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 CEH14204.1 - 0.0048 17.6 0.0 0.023 15.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 CEH14204.1 - 0.0062 15.5 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 CEH14204.1 - 0.014 15.3 0.1 0.038 14.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 CEH14204.1 - 0.039 13.3 0.3 0.083 12.2 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 CEH14204.1 - 0.056 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family C2 PF00168.30 CEH14205.1 - 2e-16 60.2 0.0 8.6e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 C2 domain PS_Dcarbxylase PF02666.15 CEH14206.1 - 2.2e-57 193.8 0.0 3.8e-57 193.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 CEH14206.1 - 2.7e-16 59.7 0.0 6.9e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 CEH14206.1 - 0.41 10.7 2.1 2.8 8.1 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain SR-25 PF10500.9 CEH14206.1 - 3 7.4 22.9 0.01 15.5 6.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TPR_1 PF00515.28 CEH14207.1 - 1.3e-52 173.6 30.2 1.8e-07 30.6 0.0 10.6 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 CEH14207.1 - 4.6e-49 160.6 25.1 1.3e-05 24.9 0.0 10.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 CEH14207.1 - 4.3e-41 135.7 17.1 3.2e-05 23.8 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.6 CEH14207.1 - 1.9e-30 102.9 9.6 0.00021 21.9 0.0 8.5 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 CEH14207.1 - 1.3e-26 90.6 4.9 0.097 12.7 0.0 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 CEH14207.1 - 1.3e-24 86.5 16.4 6.5e-05 23.4 0.3 6.8 5 1 3 8 8 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 CEH14207.1 - 1.1e-23 81.8 16.6 0.0083 16.4 0.0 10.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 CEH14207.1 - 2.9e-23 82.2 20.7 3.8e-06 27.4 0.0 8.2 5 2 2 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 CEH14207.1 - 3.4e-23 81.7 17.4 0.00017 21.8 0.7 7.7 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEH14207.1 - 1.5e-20 72.6 29.3 2.3e-06 27.2 1.6 9.7 5 2 4 9 9 9 5 TPR repeat TPR_6 PF13174.6 CEH14207.1 - 2.3e-19 68.7 16.8 0.04 14.6 0.0 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_9 PF13371.6 CEH14207.1 - 1.9e-18 66.4 8.6 0.0068 16.5 0.3 6.2 1 1 5 7 7 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH14207.1 - 5.3e-10 39.4 6.9 4.7e-05 23.5 1.8 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CEH14207.1 - 7e-07 28.7 9.3 0.2 10.8 1.0 5.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 CEH14207.1 - 9.8e-05 22.1 10.4 0.75 9.5 0.6 5.1 4 3 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CEH14207.1 - 0.00072 19.3 16.7 12 5.9 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat ChAPs PF09295.10 CEH14207.1 - 0.063 12.3 0.3 9.2 5.1 0.1 2.5 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.9 CEH14207.1 - 0.069 12.9 2.6 6 6.5 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TOM20_plant PF06552.12 CEH14207.1 - 0.19 11.4 3.3 18 5.0 0.0 3.9 4 2 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 SNAP PF14938.6 CEH14207.1 - 0.27 10.6 15.7 5.7 6.3 0.2 4.7 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP BTAD PF03704.17 CEH14207.1 - 0.31 11.5 4.7 6.7 7.1 0.3 3.2 2 2 1 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 CEH14207.1 - 0.33 11.3 6.4 0.56 10.6 0.1 4.2 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 CEH14207.1 - 7.7 6.6 25.3 6.3 6.9 1.4 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat T7SS_ESX_EspC PF10824.8 CEH14209.1 - 0.032 14.7 0.4 0.041 14.4 0.4 1.2 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm tRNA_m1G_MT PF01746.21 CEH14210.1 - 4e-22 78.9 0.0 2e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase DUF1682 PF07946.14 CEH14210.1 - 1.8 7.7 6.5 3.1 6.9 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HSF_DNA-bind PF00447.17 CEH14211.1 - 3.2e-25 88.6 0.1 6e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Sigma70_ner PF04546.13 CEH14211.1 - 0.9 9.4 0.0 0.9 9.4 0.0 4.6 3 1 1 4 4 4 0 Sigma-70, non-essential region E1-E2_ATPase PF00122.20 CEH14212.1 - 3.5e-39 134.2 0.2 9e-39 132.9 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CEH14212.1 - 8.5e-28 98.1 0.1 2.8e-27 96.4 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CEH14212.1 - 2.2e-14 53.6 14.0 0.001 19.5 0.0 5.7 5 1 1 6 6 6 4 Heavy-metal-associated domain HAD PF12710.7 CEH14212.1 - 1.1e-06 29.2 0.0 2.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CEH14212.1 - 0.00044 20.1 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1658 PF07871.11 CEH14212.1 - 0.028 14.3 0.1 0.13 12.3 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) Sulfate_transp PF00916.20 CEH14213.1 - 1.3e-61 208.5 14.3 2e-61 207.9 14.3 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 CEH14213.1 - 6e-14 51.9 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 CEH14213.1 - 5.4e-12 45.4 0.1 9.7e-12 44.6 0.1 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CEH14213.1 - 0.00059 20.2 13.5 0.019 15.3 2.8 3.1 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily UCR_UQCRX_QCR9 PF05365.12 CEH14213.1 - 0.093 12.7 0.0 0.33 10.9 0.0 2.0 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Ras PF00071.22 CEH14214.1 - 1.5e-54 184.0 0.0 1.8e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH14214.1 - 3.6e-31 107.9 0.0 5.2e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH14214.1 - 5.8e-12 45.4 0.0 7.3e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEH14214.1 - 1.5e-07 31.5 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEH14214.1 - 7.5e-06 25.5 0.0 9.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEH14214.1 - 2.4e-05 24.3 0.0 0.0015 18.5 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CEH14214.1 - 0.00014 21.5 0.0 0.0019 17.8 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CEH14214.1 - 0.0029 17.0 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 CEH14214.1 - 0.0083 16.1 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CEH14214.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CEH14214.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 CEH14214.1 - 0.012 15.4 0.1 0.43 10.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CEH14214.1 - 0.013 15.2 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CEH14214.1 - 0.017 14.7 0.0 0.042 13.4 0.0 1.6 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CEH14214.1 - 0.018 15.3 0.0 0.033 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CEH14214.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CEH14214.1 - 0.028 13.7 0.1 0.45 9.8 0.0 2.2 2 0 0 2 2 2 0 Septin ATPase_2 PF01637.18 CEH14214.1 - 0.042 13.8 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CEH14214.1 - 0.048 14.2 0.0 0.095 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 CEH14214.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 CEH14214.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NTPase_1 PF03266.15 CEH14214.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 CEH14214.1 - 0.19 11.5 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Csm1 PF12539.8 CEH14215.1 - 3e-11 43.8 0.0 5.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 SHE3 PF17078.5 CEH14215.1 - 0.0062 16.3 1.1 0.01 15.6 1.1 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Lzipper-MIP1 PF14389.6 CEH14215.1 - 0.11 12.8 0.4 0.11 12.8 0.4 2.8 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 MDM10 PF12519.8 CEH14215.1 - 0.12 11.3 6.0 0.2 10.5 6.0 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Cep57_CLD_2 PF14197.6 CEH14215.1 - 0.18 11.9 14.9 6.2 7.0 2.7 4.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 XhlA PF10779.9 CEH14215.1 - 0.34 11.1 1.9 11 6.3 0.1 2.8 2 0 0 2 2 2 0 Haemolysin XhlA Dmrt1 PF12374.8 CEH14215.1 - 0.49 10.9 4.2 12 6.5 0.4 2.9 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 Mt_ATP-synt_D PF05873.12 CEH14215.1 - 0.94 9.3 5.7 12 5.8 0.1 3.2 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) FapA PF03961.13 CEH14215.1 - 1.4 7.4 5.5 0.64 8.6 3.0 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 CEH14215.1 - 2.1 8.3 11.5 1.2 9.1 1.0 3.6 2 1 0 3 3 3 0 Prefoldin subunit DUF4407 PF14362.6 CEH14215.1 - 7.9 5.7 24.5 13 5.0 23.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 CEH14215.1 - 8.1 6.9 7.2 9.6 6.7 0.6 3.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) JIP_LZII PF16471.5 CEH14215.1 - 9.7 6.4 9.4 1.3 9.2 1.1 3.2 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Actin PF00022.19 CEH14216.1 - 3.7e-54 183.9 0.0 5.4e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 Actin DUF3040 PF11239.8 CEH14216.1 - 0.1 12.9 0.1 0.1 12.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Chitin_synth_2 PF03142.15 CEH14217.1 - 5.6e-247 820.5 0.1 7.3e-247 820.1 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CEH14217.1 - 1.4e-12 48.1 0.4 1.1e-11 45.1 0.3 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEH14217.1 - 1.3e-10 41.6 5.7 1.3e-10 41.6 5.7 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 CEH14217.1 - 0.00098 18.6 0.4 0.87 9.0 0.1 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 DSPc PF00782.20 CEH14219.1 - 6.4e-05 22.8 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CEH14219.1 - 0.015 15.4 0.0 0.049 13.7 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.12 CEH14219.1 - 0.038 13.7 0.2 0.067 12.9 0.2 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 CEH14219.1 - 0.1 12.1 1.6 0.71 9.4 1.6 2.0 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Nodulin_late PF07127.11 CEH14222.1 - 0.042 14.2 0.2 0.068 13.5 0.2 1.3 1 0 0 1 1 1 0 Late nodulin protein Ferrochelatase PF00762.19 CEH14224.1 - 9.4e-107 356.7 0.0 1.1e-106 356.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 CEH14224.1 - 0.01 16.1 0.0 4.4 7.7 0.0 2.6 2 0 0 2 2 2 0 CbiX zf-RING_2 PF13639.6 CEH14225.1 - 4.3e-15 55.8 6.8 7e-15 55.1 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEH14225.1 - 3.3e-13 49.7 3.8 6.7e-13 48.7 3.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEH14225.1 - 1.1e-11 44.4 7.3 1.9e-11 43.6 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEH14225.1 - 6.8e-10 38.7 6.3 6.8e-10 38.7 6.3 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEH14225.1 - 7.4e-10 38.4 1.9 1.4e-09 37.5 1.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CEH14225.1 - 8.7e-10 38.5 2.7 1.5e-09 37.7 2.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEH14225.1 - 6.3e-08 32.4 3.2 1.1e-07 31.6 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH14225.1 - 1.9e-07 30.9 3.9 2.9e-07 30.3 3.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEH14225.1 - 3.9e-07 30.0 1.2 7.3e-07 29.2 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CEH14225.1 - 7.9e-05 22.7 2.8 0.00016 21.8 2.8 1.5 1 1 0 1 1 1 1 RING-variant domain PHD PF00628.29 CEH14225.1 - 0.00011 22.0 3.5 0.00073 19.4 4.1 1.9 2 0 0 2 2 2 1 PHD-finger Prok-RING_4 PF14447.6 CEH14225.1 - 0.00011 21.9 6.9 0.0031 17.3 6.5 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CEH14225.1 - 0.00038 20.0 2.0 0.00072 19.1 2.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 CEH14225.1 - 0.0027 17.5 5.3 0.0061 16.3 5.1 1.7 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 CEH14225.1 - 0.0037 17.0 1.6 0.0061 16.4 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 CEH14225.1 - 0.0048 17.1 5.8 0.018 15.2 5.8 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING-like PF08746.11 CEH14225.1 - 0.016 15.5 3.2 0.016 15.5 3.2 2.2 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_4 PF15227.6 CEH14225.1 - 0.037 14.2 3.2 0.1 12.8 3.2 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 CEH14225.1 - 0.088 12.9 2.3 0.16 12.1 2.3 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger Tmpp129 PF10272.9 CEH14225.1 - 0.14 11.4 0.5 0.22 10.8 0.5 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Zn-C2H2_12 PF18112.1 CEH14225.1 - 0.19 12.2 2.1 5.2 7.6 0.4 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_9 PF13901.6 CEH14225.1 - 0.25 11.3 2.8 0.35 10.8 2.8 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zinc_ribbon_16 PF17034.5 CEH14225.1 - 0.3 11.3 3.8 0.29 11.3 2.2 1.8 1 1 1 2 2 2 0 Zinc-ribbon like family Prok-RING_1 PF14446.6 CEH14225.1 - 0.4 10.6 2.9 1.1 9.3 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-P11 PF03854.14 CEH14225.1 - 2.1 8.1 6.8 0.81 9.4 1.4 2.2 1 1 1 2 2 2 0 P-11 zinc finger zf-C3H2C3 PF17122.5 CEH14225.1 - 3.3 7.8 8.8 0.34 11.0 2.8 2.3 2 1 0 2 2 2 0 Zinc-finger SIN1_PH PF16979.5 CEH14227.1 - 1.4e-24 86.4 0.0 2.1e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 CEH14227.1 - 0.00063 19.9 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 TUG ubiquitin-like domain RA PF00788.23 CEH14227.1 - 0.0011 19.6 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RBD PF02196.15 CEH14227.1 - 0.0035 17.4 0.1 0.0065 16.5 0.1 1.5 1 0 0 1 1 1 1 Raf-like Ras-binding domain CRIM PF16978.5 CEH14228.1 - 8.3e-33 113.5 0.0 1.4e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain Glyco_transf_15 PF01793.16 CEH14230.1 - 4.8e-117 390.8 5.9 5.7e-117 390.6 5.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RPN7 PF10602.9 CEH14231.1 - 2.5e-45 154.3 0.6 3.5e-45 153.8 0.6 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CEH14231.1 - 5.9e-15 55.7 0.0 1.9e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CEH14231.1 - 0.00046 20.2 0.0 0.00081 19.4 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Ribonuc_2-5A PF06479.12 CEH14233.1 - 7.6e-41 139.3 0.0 1.4e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 CEH14233.1 - 1.4e-37 129.5 0.0 1.9e-35 122.5 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH14233.1 - 2.5e-18 66.3 0.0 5.2e-18 65.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH14233.1 - 8.3e-05 21.5 0.0 0.00044 19.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CEH14233.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH14233.1 - 0.019 14.9 0.1 0.056 13.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CEH14233.1 - 0.025 14.1 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL BC10 PF06726.12 CEH14234.1 - 8.9e-11 41.9 9.0 2.1e-10 40.6 9.0 1.6 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Polysacc_deac_1 PF01522.21 CEH14235.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase CX9C PF16860.5 CEH14238.1 - 2.6e-13 49.7 2.8 9.2e-11 41.6 1.3 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 CEH14238.1 - 0.0039 17.5 2.4 0.5 10.7 0.3 2.3 1 1 0 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 CEH14238.1 - 0.0095 15.9 3.5 0.26 11.3 0.7 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 CEH14238.1 - 0.012 15.8 2.8 1.8 8.9 2.9 2.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 CEH14238.1 - 0.015 15.5 3.3 0.35 11.1 0.9 2.2 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.13 CEH14238.1 - 0.019 15.1 3.3 0.082 13.1 1.2 2.6 2 1 1 3 3 3 0 CHCH domain Pet191_N PF10203.9 CEH14238.1 - 1.2 9.5 5.6 20 5.6 1.1 2.5 1 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 FF PF01846.19 CEH14239.1 - 2.4e-26 91.7 15.7 8.7e-05 22.6 3.6 6.4 5 1 0 5 5 5 5 FF domain WW PF00397.26 CEH14239.1 - 3.7e-08 33.3 4.4 3.7e-08 33.3 4.4 2.6 2 0 0 2 2 2 1 WW domain RhoGAP-FF1 PF16512.5 CEH14239.1 - 9.4e-06 26.2 5.7 0.03 15.0 0.8 3.2 2 0 0 2 2 2 2 p190-A and -B Rho GAPs FF domain DNA_pol_E_B PF04042.16 CEH14239.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B HECT PF00632.25 CEH14240.1 - 9.4e-96 320.9 0.0 1.2e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AAA PF00004.29 CEH14241.1 - 9.1e-32 110.2 0.2 2.1e-31 109.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEH14241.1 - 1.6e-08 34.9 0.3 7.7e-08 32.7 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEH14241.1 - 9.1e-07 29.4 0.1 3.4e-06 27.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CEH14241.1 - 1.1e-06 28.8 0.0 3.1e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEH14241.1 - 6.7e-06 26.7 0.0 1.3e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CEH14241.1 - 1.2e-05 24.9 0.3 0.019 14.6 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 CEH14241.1 - 1.3e-05 25.4 0.0 2.8e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 CEH14241.1 - 3.1e-05 23.9 0.1 0.0005 20.0 0.1 2.4 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 CEH14241.1 - 4.2e-05 23.6 0.1 0.041 13.8 0.1 2.2 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CEH14241.1 - 5.6e-05 23.2 0.0 9.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CEH14241.1 - 0.00024 20.9 0.0 0.00047 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CEH14241.1 - 0.00035 20.6 0.2 0.0012 18.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 CEH14241.1 - 0.00046 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CEH14241.1 - 0.00047 19.9 0.1 0.0013 18.5 0.1 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 CEH14241.1 - 0.00064 19.6 0.1 0.0015 18.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CEH14241.1 - 0.0007 19.9 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CEH14241.1 - 0.00074 19.9 0.0 0.0021 18.4 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_30 PF13604.6 CEH14241.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CEH14241.1 - 0.0019 18.7 0.0 0.0037 17.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.18 CEH14241.1 - 0.0021 17.9 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CEH14241.1 - 0.0031 17.5 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 CEH14241.1 - 0.0033 17.2 0.1 0.007 16.1 0.1 1.7 1 1 0 1 1 1 1 Cytidylate kinase IstB_IS21 PF01695.17 CEH14241.1 - 0.0035 17.1 0.0 0.0084 15.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.6 CEH14241.1 - 0.0071 16.8 0.0 0.016 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CEH14241.1 - 0.0098 15.1 0.1 0.12 11.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CEH14241.1 - 0.0099 15.3 0.0 0.029 13.8 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CEH14241.1 - 0.011 16.1 0.5 0.046 14.0 0.1 2.1 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 CEH14241.1 - 0.015 15.2 0.7 0.066 13.1 0.0 2.1 1 1 1 2 2 2 0 NTPase TIP49 PF06068.13 CEH14241.1 - 0.017 14.4 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_13 PF13166.6 CEH14241.1 - 0.018 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad51 PF08423.11 CEH14241.1 - 0.019 14.2 0.3 1.4 8.1 0.1 2.1 1 1 1 2 2 2 0 Rad51 Cas3_C PF18395.1 CEH14241.1 - 0.023 15.2 0.4 1.3 9.6 0.0 3.2 4 0 0 4 4 2 0 Cas3 C-terminal domain AAA_7 PF12775.7 CEH14241.1 - 0.028 13.9 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 CEH14241.1 - 0.033 13.4 0.0 1.8 7.7 0.0 2.3 1 1 0 2 2 2 0 KAP family P-loop domain ATPase PF06745.13 CEH14241.1 - 0.043 13.1 0.0 0.18 11.1 0.0 1.9 1 1 0 1 1 1 0 KaiC PduV-EutP PF10662.9 CEH14241.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 CEH14241.1 - 0.056 12.9 0.1 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 CEH14241.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CEH14241.1 - 0.069 13.1 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF2075 PF09848.9 CEH14241.1 - 0.071 12.3 0.0 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 CEH14241.1 - 0.076 12.6 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.26 CEH14241.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 CEH14241.1 - 0.093 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 CEH14241.1 - 0.094 13.2 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 CEH14241.1 - 0.18 11.3 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 COesterase PF00135.28 CEH14242.1 - 1.4e-05 24.2 0.0 1.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CEH14242.1 - 3.4e-05 23.8 0.0 0.00016 21.6 0.1 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEH14242.1 - 0.00067 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CEH14242.1 - 0.011 15.6 0.0 0.039 13.8 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CEH14242.1 - 0.043 13.1 0.0 0.095 11.9 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEH14242.1 - 0.36 11.4 4.5 0.44 11.1 4.5 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.7 CEH14243.1 - 1.1e-08 34.8 3.3 1.7e-08 34.2 3.3 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEH14243.1 - 0.00037 20.3 1.3 0.00062 19.6 1.3 1.3 1 0 0 1 1 1 1 F-box domain UQ_con PF00179.26 CEH14244.1 - 8.7e-05 22.2 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DASH_Dad3 PF08656.10 CEH14245.1 - 2.6e-21 75.5 1.0 3.4e-21 75.1 1.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 AftA_C PF12249.8 CEH14245.1 - 0.051 13.2 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal PAP_assoc PF03828.19 CEH14246.1 - 1.5e-15 57.2 0.0 3.2e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CEH14246.1 - 1.1e-07 32.1 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CEH14246.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Aminotran_4 PF01063.19 CEH14247.1 - 2.8e-28 99.3 0.0 6.8e-28 98.0 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV LCD1 PF09798.9 CEH14250.1 - 0.073 11.6 3.5 0.089 11.3 3.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein PIEZO PF15917.5 CEH14250.1 - 0.88 9.0 5.3 1.4 8.3 5.3 1.2 1 0 0 1 1 1 0 Piezo Peptidase_S49_N PF08496.10 CEH14250.1 - 1.6 8.8 5.0 2.3 8.3 5.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_23 PF13476.6 CEH14250.1 - 4.5 7.7 7.9 6.5 7.2 7.9 1.1 1 0 0 1 1 1 0 AAA domain Ribosomal_L37 PF08561.10 CEH14250.1 - 7.9 7.0 11.0 17 6.0 11.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 GREB1 PF15782.5 CEH14250.1 - 9.7 3.2 10.7 12 2.8 10.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sel1 PF08238.12 CEH14251.1 - 6e-12 45.8 20.5 2.3e-05 24.9 0.4 4.8 4 0 0 4 4 4 3 Sel1 repeat Usp PF00582.26 CEH14252.1 - 3.4e-18 66.5 0.2 6.2e-18 65.7 0.1 1.5 1 1 0 1 1 1 1 Universal stress protein family Toprim_4 PF13662.6 CEH14252.1 - 0.013 15.9 0.1 0.073 13.6 0.0 2.1 2 0 0 2 2 2 0 Toprim domain WW_like PF17890.1 CEH14252.1 - 0.014 15.5 0.0 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Peptidoglycan hydrolase LytB WW-like domain DNA_photolyase PF00875.18 CEH14252.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 DNA photolyase Peptidase_S24 PF00717.23 CEH14254.1 - 0.055 13.4 0.1 0.07 13.1 0.1 1.1 1 0 0 1 1 1 0 Peptidase S24-like Peptidase_S9 PF00326.21 CEH14255.1 - 1.5e-39 135.7 0.0 3e-39 134.7 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CEH14255.1 - 1.3e-09 38.1 0.8 3.8e-06 26.7 0.2 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH14255.1 - 1.1e-07 31.4 0.2 0.0006 19.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 CEH14255.1 - 7.5e-07 28.9 0.0 2.5e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 CEH14255.1 - 0.00052 19.7 0.0 0.44 10.1 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 CEH14255.1 - 0.0044 17.7 2.7 0.005 17.5 1.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CEH14255.1 - 0.032 14.1 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 CEH14255.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PhoPQ_related PF10142.9 CEH14255.1 - 0.22 10.2 0.0 0.33 9.5 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Trypsin_2 PF13365.6 CEH14256.1 - 1.7e-07 32.2 1.2 0.039 14.9 0.0 3.2 2 1 1 3 3 3 2 Trypsin-like peptidase domain Peptidase_S29 PF02907.15 CEH14256.1 - 0.053 13.3 0.3 0.14 11.8 0.3 1.7 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease RNA_pol_Rpb1_1 PF04997.12 CEH14257.1 - 5.8e-103 344.5 0.0 8.5e-103 343.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CEH14257.1 - 3e-102 341.6 0.1 4.9e-102 340.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CEH14257.1 - 9.7e-74 247.1 0.0 1.8e-73 246.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CEH14257.1 - 5.1e-54 183.0 0.1 1.8e-53 181.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 CEH14257.1 - 5.5e-45 153.1 0.0 1.3e-44 151.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 CEH14257.1 - 1.3e-38 132.0 0.3 2.5e-38 131.1 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 CEH14257.1 - 2.2e-38 130.5 0.0 5.1e-38 129.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CEH14257.1 - 4.3e-15 55.2 233.0 0.004 17.4 8.2 15.9 10 3 3 16 16 16 12 RNA polymerase Rpb1 C-terminal repeat RRM_1 PF00076.22 CEH14258.1 - 1.5e-31 108.1 0.0 4.7e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEH14258.1 - 0.0031 17.3 0.0 0.0089 15.9 0.0 1.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CEH14258.1 - 0.097 12.8 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif MRC1 PF09444.10 CEH14261.1 - 3.1e-25 89.4 20.6 3.1e-25 89.4 20.6 6.9 5 1 1 6 6 6 2 MRC1-like domain Cyto_heme_lyase PF01265.17 CEH14262.1 - 1.6e-39 136.2 12.5 5.5e-37 127.9 2.8 2.7 1 1 0 2 2 2 2 Cytochrome c/c1 heme lyase SAGA-Tad1 PF12767.7 CEH14263.1 - 3e-42 145.0 0.0 9.7e-42 143.3 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit FAM165 PF14981.6 CEH14263.1 - 0.041 13.7 0.3 0.078 12.8 0.3 1.4 1 0 0 1 1 1 0 FAM165 family BPL_N PF09825.9 CEH14264.1 - 1.4e-75 254.8 0.0 2.4e-75 254.0 0.0 1.4 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 CEH14264.1 - 2.6e-19 69.4 0.0 5.4e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CEH14264.1 - 0.084 12.8 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 Biotin protein ligase C terminal domain GATase_3 PF07685.14 CEH14264.1 - 0.092 12.3 0.0 0.42 10.2 0.0 1.8 1 1 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Proteasome PF00227.26 CEH14265.1 - 9.1e-50 168.8 0.3 1.1e-49 168.5 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF4116 PF13475.6 CEH14265.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) NCBP3 PF10309.9 CEH14266.1 - 4.9e-12 45.5 0.0 7.7e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Cation_efflux PF01545.21 CEH14267.1 - 8.9e-17 61.5 4.7 1.1e-16 61.1 4.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CEH14267.1 - 7.2e-11 42.1 0.0 3.9e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter Asp PF00026.23 CEH14269.1 - 8.1e-35 120.7 0.0 7.8e-34 117.5 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEH14269.1 - 2.7e-16 60.3 0.3 5.6e-15 56.0 0.4 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CEH14269.1 - 0.00013 22.6 0.1 1.6 9.4 0.0 3.5 3 0 0 3 3 3 1 Aspartyl protease SASP PF00269.20 CEH14269.1 - 0.013 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type gag-asp_proteas PF13975.6 CEH14269.1 - 0.016 15.7 0.0 16 6.1 0.0 3.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease PetG PF02529.15 CEH14270.1 - 0.05 13.5 1.4 0.1 12.4 0.1 2.1 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 DUF2415 PF10313.9 CEH14271.1 - 3.4e-06 26.9 0.0 1e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 CEH14271.1 - 4.2e-06 27.0 0.0 0.073 13.4 0.0 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CEH14271.1 - 0.00031 20.6 1.7 0.99 9.4 0.2 4.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 CEH14271.1 - 0.017 14.5 0.2 0.078 12.3 0.1 2.0 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 CEH14271.1 - 0.017 14.1 0.1 0.13 11.2 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 CEH14271.1 - 0.042 14.7 4.8 0.17 12.8 0.3 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat DPPIV_N PF00930.21 CEH14271.1 - 0.11 11.3 0.1 1.6 7.4 0.0 2.1 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region NOA36 PF06524.12 CEH14271.1 - 0.25 10.6 3.6 0.39 10.0 3.6 1.2 1 0 0 1 1 1 0 NOA36 protein ArsB PF02040.15 CEH14272.1 - 1.7e-08 34.2 3.2 1.7e-08 34.2 3.2 1.6 2 0 0 2 2 2 1 Arsenical pump membrane protein Pkinase PF00069.25 CEH14273.1 - 4.6e-42 144.2 0.1 1.8e-21 76.7 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH14273.1 - 9.5e-12 44.7 0.4 3.6e-08 33.0 0.2 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Metallophos PF00149.28 CEH14274.1 - 7.4e-11 42.9 0.0 2.5e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEH14274.1 - 1e-06 29.0 0.1 2.1e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Urease_linker PF18473.1 CEH14275.1 - 0.014 15.3 7.2 0.36 10.7 1.0 2.5 2 0 0 2 2 2 0 Urease subunit beta-alpha linker domain LIAS_N PF16881.5 CEH14276.1 - 1.3e-15 57.7 0.0 3.2e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CEH14276.1 - 2.2e-11 44.4 0.0 3.6e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Lactamase_B PF00753.27 CEH14278.1 - 4.7e-12 46.3 0.4 1e-11 45.3 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEH14278.1 - 4.3e-05 23.1 1.0 0.00017 21.2 0.2 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain FAM199X PF15814.5 CEH14278.1 - 0.06 12.4 0.2 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X F-box-like PF12937.7 CEH14279.1 - 0.056 13.3 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 F-box-like Epimerase PF01370.21 CEH14280.1 - 4.8e-18 65.5 0.1 1.1e-17 64.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CEH14280.1 - 5e-10 39.6 0.1 1e-09 38.5 0.0 1.6 1 1 1 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CEH14280.1 - 5.3e-08 32.6 0.1 6.3e-07 29.1 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CEH14280.1 - 8.2e-07 28.8 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 CEH14280.1 - 8.9e-07 28.3 0.0 2.3e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 CEH14280.1 - 1.6e-05 24.1 0.0 3.2e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 CEH14280.1 - 0.00043 20.5 0.0 0.00079 19.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 CEH14280.1 - 0.00064 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 CEH14280.1 - 0.01 15.0 0.5 0.028 13.6 0.2 1.8 1 1 0 2 2 2 0 Male sterility protein adh_short PF00106.25 CEH14280.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_2 PF03446.15 CEH14280.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase tRNA_U5-meth_tr PF05958.11 CEH14281.1 - 2e-20 73.1 0.0 2.4e-19 69.5 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CEH14281.1 - 3.7e-08 33.3 0.0 7.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH14281.1 - 4e-06 27.4 0.0 1.4e-05 25.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CEH14281.1 - 1.9e-05 24.3 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 CEH14281.1 - 9.8e-05 22.9 0.0 0.00022 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEH14281.1 - 0.00013 21.5 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 CEH14281.1 - 0.00049 19.8 0.1 0.0023 17.6 0.0 2.1 3 0 0 3 3 3 1 Conserved hypothetical protein 95 PrmA PF06325.13 CEH14281.1 - 0.0045 16.4 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 CEH14281.1 - 0.0071 15.7 0.0 0.059 12.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 CEH14281.1 - 0.0076 16.0 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TPMT PF05724.11 CEH14281.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 CEH14281.1 - 0.16 11.4 0.0 0.46 9.9 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase NAM-associated PF14303.6 CEH14281.1 - 0.81 10.4 8.5 1.3 9.7 8.5 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Porphobil_deam PF01379.20 CEH14282.1 - 7.1e-66 221.6 0.0 2.3e-61 206.9 0.0 2.3 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CEH14282.1 - 2.8e-15 56.4 0.8 7.9e-09 35.8 0.1 3.3 3 0 0 3 3 3 2 Porphobilinogen deaminase, C-terminal domain Requiem_N PF14051.6 CEH14283.1 - 0.027 14.7 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. NUDIX PF00293.28 CEH14286.1 - 2.3e-05 24.4 0.0 0.00011 22.3 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain PEP_mutase PF13714.6 CEH14286.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase GET2 PF08690.10 CEH14288.1 - 7.6e-09 35.7 0.0 0.005 16.6 0.4 2.5 2 1 0 2 2 2 2 GET complex subunit GET2 DUF5310 PF17237.2 CEH14289.1 - 9.8e-19 67.0 3.3 1.1e-18 66.7 3.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) KH_1 PF00013.29 CEH14290.1 - 3.1e-34 116.6 0.1 3.8e-08 33.0 0.0 6.8 7 0 0 7 7 7 5 KH domain RhoGAP PF00620.27 CEH14291.1 - 2.8e-47 160.4 0.1 2.6e-46 157.2 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 CEH14291.1 - 1.1e-15 57.5 30.0 5e-09 36.3 3.2 3.4 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 CEH14291.1 - 2.7e-06 27.2 7.5 2.7e-06 27.2 7.5 4.0 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Suppressor_APC PF11414.8 CEH14291.1 - 0.037 14.1 4.3 0.16 12.1 4.3 2.1 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein ZnuA PF01297.17 CEH14291.1 - 0.044 13.2 0.2 0.11 11.9 0.2 1.6 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF3541 PF12060.8 CEH14291.1 - 0.8 9.3 3.7 1.8 8.2 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) Paired_CXXCH_1 PF09699.10 CEH14291.1 - 4.2 7.2 10.8 1.9 8.3 2.1 3.0 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Fungal_TACC PF12709.7 CEH14291.1 - 5.6 7.5 8.1 0.51 10.8 1.0 2.6 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins SRR1 PF07985.12 CEH14292.1 - 4.3e-11 42.7 0.0 7.8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 SRR1 DUF155 PF02582.14 CEH14293.1 - 1.4e-48 165.3 0.0 2.5e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 IPP-2 PF04979.14 CEH14293.1 - 0.47 11.2 8.1 0.7 10.6 0.3 2.3 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) DUF908 PF06012.12 CEH14293.1 - 2.1 7.7 5.0 3.6 6.9 5.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Spt5_N PF11942.8 CEH14293.1 - 2.8 9.0 12.2 2.9 9.0 1.7 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal NADH_B2 PF14813.6 CEH14294.1 - 0.0012 18.6 0.3 0.0015 18.2 0.3 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 COX7B PF05392.11 CEH14294.1 - 0.18 11.5 1.0 0.3 10.8 0.0 1.8 1 1 1 2 2 2 0 Cytochrome C oxidase chain VIIB QLQ PF08880.11 CEH14295.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 QLQ IQCJ-SCHIP1 PF15157.6 CEH14295.1 - 0.22 11.4 0.3 0.3 10.9 0.3 1.2 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif MAPEG PF01124.18 CEH14296.1 - 7.1e-24 84.2 1.6 8.2e-24 84.0 1.6 1.0 1 0 0 1 1 1 1 MAPEG family Lipase_GDSL_2 PF13472.6 CEH14298.1 - 0.00042 20.8 0.9 0.00072 20.0 0.9 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4015 PF13200.6 CEH14299.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain CBS PF00571.28 CEH14301.1 - 1.6e-08 34.8 0.1 0.032 14.7 0.0 4.4 4 0 0 4 4 4 2 CBS domain Acetyltransf_1 PF00583.25 CEH14302.1 - 7.8e-16 58.4 0.0 9.1e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEH14302.1 - 2.7e-10 40.2 0.1 3.1e-10 40.1 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEH14302.1 - 2e-07 31.4 0.0 2.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEH14302.1 - 7.2e-06 25.9 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CEH14302.1 - 0.00051 20.1 0.0 0.0008 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CEH14302.1 - 0.001 18.6 0.3 0.007 15.9 0.1 2.0 2 0 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 CEH14302.1 - 0.12 13.0 0.0 0.14 12.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Band_7 PF01145.25 CEH14303.1 - 1.9e-23 83.4 5.8 2.7e-23 82.9 5.2 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CEH14303.1 - 0.00011 21.4 2.5 0.00014 21.0 2.5 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF3290 PF11694.8 CEH14304.1 - 0.0063 16.5 2.8 0.067 13.2 0.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3290) SHR3_chaperone PF08229.11 CEH14305.1 - 0.0017 17.4 0.2 0.004 16.1 0.0 1.7 2 0 0 2 2 2 1 ER membrane protein SH3 Thioesterase PF00975.20 CEH14306.1 - 9.2e-12 45.6 0.9 2.1e-11 44.4 0.9 1.7 1 1 0 1 1 1 1 Thioesterase domain Glucosamine_iso PF01182.20 CEH14308.1 - 2.5e-60 204.1 0.0 3.2e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NDUF_B12 PF08122.12 CEH14309.1 - 5.7e-16 58.3 0.7 9.4e-16 57.6 0.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Inositol_P PF00459.25 CEH14310.1 - 4.4e-70 236.3 0.5 5.2e-70 236.1 0.5 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Cu_amine_oxidN1 PF07833.11 CEH14310.1 - 0.034 14.6 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 Copper amine oxidase N-terminal domain ATP-synt_B PF00430.18 CEH14310.1 - 0.04 14.0 3.0 0.053 13.6 2.0 1.6 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) SIKE PF05769.11 CEH14313.1 - 2.2e-08 34.2 9.3 1.6e-06 28.2 3.6 2.3 2 0 0 2 2 2 2 SIKE family Shugoshin_N PF07558.11 CEH14313.1 - 0.037 13.9 2.2 0.35 10.8 0.0 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region NYD-SP28_assoc PF14775.6 CEH14313.1 - 1.6 8.9 7.5 16 5.7 0.3 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain YabA PF06156.13 CEH14313.1 - 1.8 9.3 9.9 11 6.8 0.1 3.2 2 1 1 3 3 3 0 Initiation control protein YabA PikAIV_N PF18605.1 CEH14313.1 - 5.3 6.7 7.3 22 4.7 3.2 2.5 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain SKN1 PF03935.15 CEH14315.1 - 3.6e-175 583.2 0.2 2.6e-173 577.0 0.2 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 CEH14315.1 - 0.00085 18.8 0.0 0.22 11.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 FtsJ PF01728.19 CEH14316.1 - 6e-28 98.1 0.0 9e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pex24p PF06398.11 CEH14317.1 - 0.0027 16.8 3.5 0.0047 16.0 3.5 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin UBM PF14377.6 CEH14318.1 - 3.4e-25 86.7 13.7 4.4e-11 41.8 0.3 3.8 3 0 0 3 3 3 3 Ubiquitin binding region SKA1 PF07160.12 CEH14318.1 - 0.38 10.5 7.4 11 5.8 5.2 3.4 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DivIC PF04977.15 CEH14318.1 - 1.8 8.4 5.9 5.9 6.7 5.9 1.8 1 0 0 1 1 1 0 Septum formation initiator eIF-3c_N PF05470.12 CEH14318.1 - 1.9 6.7 6.6 4.6 5.4 6.6 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF908 PF06012.12 CEH14319.1 - 1.3e-78 265.0 5.7 2e-47 162.3 0.0 3.1 2 1 1 3 3 3 3 Domain of Unknown Function (DUF908) DUF913 PF06025.12 CEH14319.1 - 8e-13 48.1 0.2 5.3e-08 32.2 0.0 3.0 2 1 1 3 3 3 2 Domain of Unknown Function (DUF913) Arm PF00514.23 CEH14319.1 - 0.11 12.6 0.2 1.9 8.7 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat RsdA_SigD_bd PF16751.5 CEH14319.1 - 0.18 12.1 1.0 31 4.9 0.1 2.8 2 0 0 2 2 2 0 Anti-sigma-D factor RsdA to sigma factor binding region HYLS1_C PF15311.6 CEH14320.1 - 0.086 13.6 0.1 0.19 12.5 0.1 1.6 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus Apt1 PF10351.9 CEH14321.1 - 6.4 5.5 10.2 8.6 5.1 10.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-4CXXC_R1 PF10497.9 CEH14322.1 - 3.8e-16 59.1 10.8 6.7e-16 58.3 10.8 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 AT_hook PF02178.19 CEH14322.1 - 0.07 13.0 19.1 0.45 10.5 5.5 3.6 2 0 0 2 2 2 0 AT hook motif PAS_4 PF08448.10 CEH14322.1 - 0.27 11.5 0.0 0.27 11.5 0.0 2.9 2 1 0 2 2 2 0 PAS fold SPRY PF00622.28 CEH14324.1 - 4.3e-20 72.0 0.1 7e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 SPRY domain IBN_N PF03810.19 CEH14325.1 - 8.2e-08 32.1 0.1 2.9e-07 30.3 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 CEH14325.1 - 0.037 12.5 0.0 0.066 11.7 0.0 1.3 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus ECH_1 PF00378.20 CEH14329.1 - 8.2e-30 103.9 0.1 1.2e-29 103.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEH14329.1 - 9.1e-18 64.8 0.4 1.3e-17 64.3 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CEH14330.1 - 6.1e-48 163.3 0.7 6.6e-48 163.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEH14330.1 - 4.4e-13 49.4 1.1 1.7e-09 37.6 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Ribosomal_L44 PF00935.19 CEH14331.1 - 4.2 7.9 4.9 0.83 10.2 1.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L44 Med31 PF05669.12 CEH14334.1 - 1.4e-26 92.3 0.1 1.8e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 SOH1 Bromodomain PF00439.25 CEH14335.1 - 2.8e-31 107.4 0.4 1.4e-16 60.3 0.2 3.0 2 1 0 2 2 2 2 Bromodomain BET PF17035.5 CEH14335.1 - 5.5e-21 74.5 0.5 1.1e-20 73.6 0.5 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FlxA PF14282.6 CEH14335.1 - 0.26 11.3 2.4 1.5 8.8 0.1 3.1 3 0 0 3 3 3 0 FlxA-like protein CDC45 PF02724.14 CEH14335.1 - 1.5 7.1 5.4 2.8 6.1 5.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 CEH14336.1 - 3.7e-60 203.5 1.2 4e-58 196.9 0.1 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH14336.1 - 1.7e-16 60.3 0.0 2.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEH14336.1 - 4.2e-09 36.7 0.0 6.2e-07 29.6 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEH14336.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CEH14336.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CEH14336.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CEH14336.1 - 0.051 13.1 0.1 0.051 13.1 0.1 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF382 PF04037.13 CEH14338.1 - 4e-54 182.1 0.2 7e-54 181.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 CEH14338.1 - 1.6e-17 63.0 4.1 4.4e-17 61.7 4.1 1.8 1 0 0 1 1 1 1 PSP DNA_pol_phi PF04931.13 CEH14338.1 - 0.27 9.3 12.4 0.51 8.4 12.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi FAD_binding_3 PF01494.19 CEH14339.1 - 2.2e-11 43.6 0.7 0.0013 18.1 0.0 3.3 3 0 0 3 3 3 3 FAD binding domain Ehrlichia_rpt PF09528.10 CEH14339.1 - 0.01 15.3 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) SE PF08491.10 CEH14339.1 - 0.012 14.6 0.0 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.17 CEH14339.1 - 0.053 12.7 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TssO PF17561.2 CEH14339.1 - 0.21 11.7 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO F-box-like PF12937.7 CEH14340.1 - 0.00085 19.2 0.3 0.0025 17.7 0.3 1.9 1 0 0 1 1 1 1 F-box-like Slx4 PF09494.10 CEH14341.1 - 3.7e-12 46.0 0.0 8.6e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease Ish1 PF10281.9 CEH14341.1 - 0.00024 21.4 0.0 0.16 12.3 0.0 3.4 3 0 0 3 3 3 1 Putative stress-responsive nuclear envelope protein PG_isomerase_N PF18353.1 CEH14341.1 - 0.071 13.5 1.9 7.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Phosphoglucose isomerase N-terminal domain DNApol_Exo PF18136.1 CEH14342.1 - 5.1e-88 294.9 0.0 5.6e-78 261.9 0.0 2.5 2 0 0 2 2 2 2 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CEH14342.1 - 1.2e-45 156.2 0.0 3e-45 154.9 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family A Menin PF05053.13 CEH14343.1 - 0.4 9.0 9.8 0.13 10.6 6.6 1.6 1 1 0 1 1 1 0 Menin DUF2486 PF10667.9 CEH14343.1 - 0.96 9.6 17.7 4 7.6 17.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2486) FAD_binding_2 PF00890.24 CEH14345.1 - 1.5e-91 307.6 0.5 1.9e-91 307.2 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 CEH14345.1 - 2.5e-20 72.4 0.2 2.3e-19 69.3 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 CEH14345.1 - 3.9e-16 59.6 0.1 6.4e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CEH14345.1 - 1.5e-10 41.1 1.0 4.4e-10 39.5 1.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEH14345.1 - 2.6e-09 36.7 0.6 3.4e-08 33.1 0.4 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEH14345.1 - 4.3e-09 36.5 0.1 4.3e-09 36.5 0.1 3.0 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CEH14345.1 - 1.1e-07 31.3 0.5 0.0016 17.6 0.1 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 CEH14345.1 - 6.1e-07 28.5 3.8 3.9e-05 22.5 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 CEH14345.1 - 2.5e-05 23.7 0.0 0.062 12.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CEH14345.1 - 3.4e-05 23.2 0.1 6.6e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CEH14345.1 - 0.0022 18.5 0.7 0.026 15.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEH14345.1 - 0.0024 17.2 2.3 0.0087 15.3 2.3 1.9 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CEH14345.1 - 0.003 16.8 0.9 0.062 12.5 0.4 2.4 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 CEH14345.1 - 0.012 14.9 0.4 0.2 10.9 0.1 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 CEH14345.1 - 0.026 14.5 0.9 0.76 9.8 0.9 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 CEH14345.1 - 0.12 12.9 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding WD40 PF00400.32 CEH14346.1 - 1.3e-25 89.2 9.1 3.6e-06 27.6 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 CEH14346.1 - 1.9e-08 33.4 0.0 0.0086 14.8 0.0 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CEH14346.1 - 0.014 15.7 0.0 1.5 9.2 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CENP-F_leu_zip PF10473.9 CEH14346.1 - 1.1 9.3 8.6 1.9 8.5 8.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pyr_redox_2 PF07992.14 CEH14347.1 - 6.5e-20 71.5 0.0 1.4e-16 60.6 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEH14347.1 - 2e-08 34.6 0.0 7e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEH14347.1 - 0.0053 16.8 0.2 0.019 14.9 0.0 2.0 1 1 1 2 2 2 1 FAD-NAD(P)-binding Eno-Rase_NADH_b PF12242.8 CEH14347.1 - 0.022 14.5 0.1 12 5.8 0.0 3.2 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox_3 PF13738.6 CEH14347.1 - 0.037 13.3 0.0 0.29 10.4 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Med26 PF08711.11 CEH14348.1 - 1.3e-10 41.1 0.3 3.4e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Rgp1 PF08737.10 CEH14349.1 - 3e-88 296.8 0.0 4.9e-88 296.1 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 CEH14349.1 - 1.5e-05 25.1 0.1 0.029 14.4 0.0 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain IU_nuc_hydro PF01156.19 CEH14350.1 - 4e-28 98.9 0.5 5.2e-28 98.5 0.5 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase AAA_11 PF13086.6 CEH14351.1 - 2.2e-23 83.4 0.3 3.6e-15 56.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 CEH14351.1 - 1.1e-16 61.1 0.0 2.2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH14351.1 - 1.5e-12 48.0 0.0 3.3e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEH14351.1 - 2.9e-12 46.7 3.3 6.5e-12 45.6 0.0 3.1 3 1 0 3 3 3 1 AAA domain UvrD-helicase PF00580.21 CEH14351.1 - 6.2e-07 29.2 0.0 7e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 CEH14351.1 - 0.00029 20.9 0.0 0.00059 19.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 CEH14351.1 - 0.00055 19.5 0.0 0.0018 17.7 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein Helicase_RecD PF05127.14 CEH14351.1 - 0.00059 19.7 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 CEH14351.1 - 0.021 15.2 0.1 0.096 13.1 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 CEH14351.1 - 0.026 14.3 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase Serglycin PF04360.12 CEH14351.1 - 0.083 12.8 2.3 0.19 11.6 2.3 1.5 1 0 0 1 1 1 0 Serglycin AAA_7 PF12775.7 CEH14351.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 CEH14351.1 - 0.12 11.5 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein F-box PF00646.33 CEH14352.1 - 0.0048 16.8 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain Ig_6 PF18452.1 CEH14352.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain MCH PF02289.16 CEH14353.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Cyclohydrolase (MCH) Peptidase_M43 PF05572.13 CEH14355.1 - 4e-15 56.0 0.0 7.5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 CEH14355.1 - 8.2e-08 32.1 0.4 0.0016 18.2 0.1 2.3 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CEH14355.1 - 8.5e-08 32.6 1.1 1.3e-06 28.7 1.1 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CEH14355.1 - 2.3e-06 28.1 2.5 7.7e-05 23.2 2.5 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CEH14355.1 - 0.00067 19.5 0.6 0.0059 16.5 0.6 2.0 1 1 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.6 CEH14355.1 - 0.0029 17.5 1.6 0.0055 16.6 1.6 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CEH14355.1 - 0.005 15.8 0.8 0.0081 15.1 0.8 1.2 1 0 0 1 1 1 1 Peptidase M66 DUF4953 PF16313.5 CEH14355.1 - 0.093 11.9 0.6 0.17 11.0 0.6 1.3 1 0 0 1 1 1 0 Met-zincin Metallopep PF12044.8 CEH14355.1 - 0.098 11.2 1.8 0.17 10.5 1.8 1.2 1 0 0 1 1 1 0 Putative peptidase family Pyr_redox_2 PF07992.14 CEH14356.1 - 1.7e-41 142.4 3.6 2.3e-41 142.0 3.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 CEH14356.1 - 3e-15 55.9 0.0 6.5e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 CEH14356.1 - 3.6e-12 46.7 10.0 4.3e-11 43.2 1.7 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEH14356.1 - 1.6e-05 24.3 0.6 0.00014 21.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEH14356.1 - 0.00019 20.7 0.1 1.9 7.6 0.0 3.1 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CEH14356.1 - 0.0026 17.7 0.4 0.27 11.2 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 CEH14356.1 - 0.017 13.8 4.9 0.022 13.5 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein Amino_oxidase PF01593.24 CEH14356.1 - 0.032 13.5 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 CEH14356.1 - 0.059 12.9 0.2 10 5.6 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Reductase_C PF14759.6 CEH14356.1 - 0.065 13.8 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Reductase C-terminal FLgD_tudor PF13861.6 CEH14356.1 - 0.24 11.7 1.3 4.9 7.5 0.0 3.2 3 0 0 3 3 3 0 FlgD Tudor-like domain GPI-anchored PF10342.9 CEH14358.1 - 7.6e-10 39.4 0.5 7.6e-10 39.4 0.5 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RlaP PF10127.9 CEH14360.1 - 1.4e-14 54.3 0.0 2.8e-14 53.3 0.0 1.5 1 1 0 1 1 1 1 RNA repair pathway DNA polymerase beta family Polbeta PF18765.1 CEH14360.1 - 0.0013 18.8 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase HEPN_SAV2148 PF18725.1 CEH14360.1 - 0.037 13.4 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 SAV2148-like HEPN Na_H_Exchanger PF00999.21 CEH14361.1 - 2e-18 66.4 40.2 8.8e-08 31.3 13.4 4.1 3 1 0 3 3 3 3 Sodium/hydrogen exchanger family Na_Ala_symp PF01235.17 CEH14361.1 - 0.043 13.1 1.3 0.084 12.2 1.3 1.4 1 0 0 1 1 1 0 Sodium:alanine symporter family Sel1 PF08238.12 CEH14363.1 - 3.6e-46 154.6 16.9 2.2e-07 31.3 0.1 7.9 7 0 0 7 7 7 7 Sel1 repeat DEAD PF00270.29 CEH14364.1 - 1.1e-20 74.1 0.7 1e-19 71.0 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 CEH14364.1 - 9.3e-05 22.5 0.0 0.00048 20.2 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 CEH14364.1 - 0.038 13.0 0.0 0.081 12.0 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 CEH14364.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 CEH14364.1 - 0.11 12.7 0.3 1.5 9.1 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 CEH14364.1 - 0.13 12.6 0.1 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain rRNA_proc-arch PF13234.6 CEH14365.1 - 7e-75 252.4 0.0 1.1e-74 251.7 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 CEH14365.1 - 7.4e-55 185.1 2.0 7.4e-55 185.1 2.0 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain Cauli_AT PF03233.13 CEH14365.1 - 0.16 11.9 0.4 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Aphid transmission protein HalX PF08663.10 CEH14365.1 - 0.24 11.8 9.0 1.9 8.8 0.6 3.2 2 0 0 2 2 2 0 HalX domain KELK PF15796.5 CEH14365.1 - 0.27 11.7 7.4 0.54 10.8 1.0 3.3 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CENP-F_leu_zip PF10473.9 CEH14365.1 - 1.1 9.3 15.2 0.15 12.1 1.2 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.13 CEH14365.1 - 2.2 8.4 9.3 0.86 9.7 0.8 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein TMF_TATA_bd PF12325.8 CEH14365.1 - 3.5 7.9 10.5 1.2 9.4 0.1 3.8 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding CTP_transf_like PF01467.26 CEH14366.1 - 6.2e-25 88.1 0.0 8.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like OTU PF02338.19 CEH14367.1 - 0.0033 17.9 0.0 0.0072 16.8 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease YkyA PF10368.9 CEH14367.1 - 0.012 15.3 1.3 0.022 14.4 1.3 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Tektin PF03148.14 CEH14367.1 - 0.1 11.3 3.9 0.17 10.6 3.9 1.2 1 0 0 1 1 1 0 Tektin family Seryl_tRNA_N PF02403.22 CEH14367.1 - 0.58 10.4 5.9 1.3 9.3 5.9 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cyt-b5 PF00173.28 CEH14368.1 - 7.3e-19 67.7 0.0 1.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MAP65_ASE1 PF03999.12 CEH14369.1 - 0.026 13.2 0.7 0.038 12.7 0.7 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF3138 PF11336.8 CEH14369.1 - 0.24 10.0 5.1 0.21 10.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) BRE1 PF08647.11 CEH14369.1 - 0.76 9.9 8.9 5.7 7.1 0.3 3.0 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase eIF-3_zeta PF05091.12 CEH14370.1 - 1.6e-169 565.3 0.0 3e-169 564.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAA_hydrolase PF01557.18 CEH14371.1 - 4.5e-46 157.3 0.0 6.5e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FYDLN_acid PF09538.10 CEH14377.1 - 0.56 10.9 6.0 1.2 9.9 1.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Rho_GDI PF02115.17 CEH14384.1 - 3.2e-53 180.4 0.0 3.7e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor STATa_Ig PF18214.1 CEH14384.1 - 0.15 12.0 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain Oxidored_FMN PF00724.20 CEH14385.1 - 7.9e-43 147.0 0.0 9.7e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Nitroreductase PF00881.24 CEH14388.1 - 6.9e-07 29.5 0.1 8.3e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family CENP-B_dimeris PF09026.10 CEH14391.1 - 0.00024 21.5 0.7 0.00062 20.1 0.7 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain TFIIE-A_C PF11521.8 CEH14391.1 - 0.3 11.4 4.9 1.1 9.5 1.3 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha ELO PF01151.18 CEH14392.1 - 2e-47 161.8 12.3 2.8e-35 122.1 6.9 2.0 1 1 1 2 2 2 2 GNS1/SUR4 family FA_hydroxylase PF04116.13 CEH14392.1 - 0.032 14.6 2.5 0.032 14.6 2.5 1.7 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily MAT1 PF06391.13 CEH14393.1 - 0.16 11.8 4.8 0.44 10.3 4.8 1.7 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 GDA1_CD39 PF01150.17 CEH14395.1 - 1.8e-89 300.3 0.0 4.7e-89 299.0 0.0 1.6 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family STAG PF08514.11 CEH14396.1 - 2e-32 111.4 0.3 8.7e-32 109.4 0.3 2.2 1 0 0 1 1 1 1 STAG domain Ecm29 PF13001.7 CEH14396.1 - 0.029 13.1 0.0 0.05 12.3 0.0 1.4 1 0 0 1 1 1 0 Proteasome stabiliser E1-E2_ATPase PF00122.20 CEH14397.1 - 1.5e-28 99.6 0.7 3.8e-28 98.2 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CEH14397.1 - 5.3e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) P5-ATPase PF12409.8 CEH14397.1 - 8.6e-06 25.9 2.7 2.3e-05 24.5 0.1 2.7 2 0 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_C PF00689.21 CEH14397.1 - 4.3e-05 23.3 7.0 4.3e-05 23.3 7.0 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CEH14397.1 - 0.00048 20.5 1.8 0.0018 18.6 1.8 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Gas_vesicle_C PF01304.17 CEH14400.1 - 1 9.4 2.6 1.9 8.5 2.6 1.5 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain BCAS2 PF05700.11 CEH14402.1 - 7.3e-57 192.4 2.6 8.7e-57 192.1 2.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) ZapB PF06005.12 CEH14402.1 - 0.053 14.0 2.5 0.053 14.0 2.5 2.7 3 0 0 3 3 3 0 Cell division protein ZapB Enkurin PF13864.6 CEH14402.1 - 0.22 12.0 7.9 0.2 12.1 5.5 2.1 2 1 0 2 2 2 0 Calmodulin-binding Seryl_tRNA_N PF02403.22 CEH14402.1 - 7.3 6.9 8.1 31 4.9 0.1 3.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2013 PF09431.10 CEH14403.1 - 3e-52 176.4 3.3 4.8e-52 175.8 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) RrnaAD PF00398.20 CEH14404.1 - 3e-21 75.7 0.0 6.6e-21 74.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase ACBP PF00887.19 CEH14405.1 - 3.7e-24 84.8 0.0 6.6e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein PMI_typeI PF01238.21 CEH14406.1 - 1.3e-110 370.1 0.0 2e-98 330.0 0.0 2.1 1 1 1 2 2 2 2 Phosphomannose isomerase type I Bombinin PF05298.11 CEH14406.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Bombinin Methyltransf_25 PF13649.6 CEH14408.1 - 7.3e-11 42.6 0.0 7.7e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH14408.1 - 4.7e-10 39.5 0.0 6.1e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEH14408.1 - 1e-08 34.8 0.1 4.5e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CEH14408.1 - 6.1e-08 32.7 0.0 8.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CEH14408.1 - 1.1e-07 31.6 0.1 1.7e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CEH14408.1 - 1.6e-07 32.0 0.1 4e-07 30.7 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH14408.1 - 1.7e-07 31.2 0.0 1.1e-05 25.4 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH14408.1 - 1.2e-06 29.1 0.0 1.6e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CEH14408.1 - 5.4e-05 22.6 0.0 7.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 CEH14408.1 - 0.00033 20.7 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 CEH14408.1 - 0.00069 19.3 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DREV PF05219.12 CEH14408.1 - 0.0015 17.7 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 CEH14408.1 - 0.0051 16.4 0.2 0.0094 15.6 0.2 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 CEH14408.1 - 0.007 15.8 0.1 0.0097 15.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 CEH14408.1 - 0.026 14.1 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 CheR PF01739.18 CEH14408.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.11 CEH14408.1 - 0.15 11.0 0.0 0.46 9.4 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1698) DnaJ PF00226.31 CEH14409.1 - 1.2e-16 60.6 0.4 2.1e-16 59.8 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain CcmD PF04995.14 CEH14409.1 - 0.084 13.0 0.1 0.084 13.0 0.1 2.3 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Glyco_transf_15 PF01793.16 CEH14409.1 - 0.16 11.2 0.1 0.22 10.7 0.1 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase SDA1 PF05285.12 CEH14411.1 - 2.6e-84 283.6 34.1 2.6e-84 283.6 34.1 2.0 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 CEH14411.1 - 1.8e-18 66.6 0.8 4.6e-18 65.3 0.1 2.2 3 0 0 3 3 3 1 NUC130/3NT domain BATS PF06968.13 CEH14412.1 - 7.9e-20 70.8 0.2 1.9e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 CEH14412.1 - 1.5e-12 48.2 0.0 2.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily U3_assoc_6 PF08640.11 CEH14415.1 - 1.5e-16 60.2 6.0 3.3e-14 52.7 0.7 3.2 3 0 0 3 3 3 2 U3 small nucleolar RNA-associated protein 6 RecX PF02631.16 CEH14415.1 - 0.014 15.8 0.2 0.054 14.0 0.2 2.0 1 0 0 1 1 1 0 RecX family TPR_19 PF14559.6 CEH14415.1 - 0.019 15.4 1.4 2.1 8.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Pmp3 PF01679.17 CEH14416.1 - 7.1e-24 83.8 7.9 7.9e-24 83.6 7.9 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RPN6_N PF18055.1 CEH14417.1 - 1.3e-36 125.5 5.9 1.9e-36 125.0 4.5 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CEH14417.1 - 1.6e-20 73.6 0.0 6.2e-20 71.7 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 CEH14417.1 - 2.1e-12 46.5 0.2 4.6e-12 45.4 0.2 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 CEH14417.1 - 0.044 13.1 12.4 0.14 11.5 11.0 2.0 1 1 0 1 1 1 0 MalT-like TPR region TPR_7 PF13176.6 CEH14417.1 - 0.17 12.0 8.3 31 4.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat GlutR_dimer PF00745.20 CEH14417.1 - 0.93 10.0 6.7 1.2 9.7 0.4 3.4 3 1 1 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain TPR_12 PF13424.6 CEH14417.1 - 2.4 8.5 12.6 48 4.3 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2203 PF09969.9 CEH14417.1 - 3.4 8.4 5.3 2.8 8.7 0.0 2.9 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Ribosomal_S11 PF00411.19 CEH14418.1 - 2e-09 37.8 0.1 4.9e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 zf-met PF12874.7 CEH14420.1 - 0.00056 20.2 2.0 0.00099 19.4 2.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEH14420.1 - 0.0015 18.8 0.9 0.0024 18.1 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF2015 PF09435.10 CEH14420.1 - 0.031 14.2 0.1 0.031 14.2 0.1 1.7 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2015) DUF678 PF05077.12 CEH14420.1 - 0.15 12.2 1.8 0.26 11.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF678) TMCO5 PF14992.6 CEH14421.1 - 0.078 12.6 2.2 0.12 12.0 2.2 1.2 1 0 0 1 1 1 0 TMCO5 family DUF641 PF04859.12 CEH14421.1 - 0.08 13.3 1.4 0.16 12.3 1.4 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CorA PF01544.18 CEH14421.1 - 0.092 12.0 2.0 0.15 11.3 2.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 CEH14421.1 - 0.098 12.7 2.2 0.2 11.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cortex-I_coil PF09304.10 CEH14421.1 - 0.18 12.0 3.1 0.35 11.1 3.1 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil Spc24 PF08286.11 CEH14421.1 - 0.38 11.0 3.3 0.85 9.9 3.3 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ADIP PF11559.8 CEH14421.1 - 2.8 8.0 7.6 5.4 7.1 7.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Sas10 PF09368.10 CEH14424.1 - 7.8e-21 74.3 4.8 3.3e-20 72.3 4.8 2.2 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CEH14424.1 - 1.2e-06 29.0 4.3 1.4e-06 28.8 0.1 2.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Cyt-b5 PF00173.28 CEH14425.1 - 6.8e-12 45.4 0.0 9.3e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FtsJ PF01728.19 CEH14426.1 - 6.3e-37 127.4 0.0 8.4e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Histone PF00125.24 CEH14427.1 - 5.2e-51 172.4 1.7 5.8e-51 172.3 1.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CEH14427.1 - 3.1e-05 24.3 0.0 4.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CEH14427.1 - 0.00011 22.3 0.3 0.00018 21.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CEH14427.1 - 0.00057 20.5 1.9 0.00073 20.1 1.9 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CEH14427.1 - 0.0059 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CEH14427.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF1769 PF08588.10 CEH14428.1 - 2.8e-15 56.2 0.2 5.4e-15 55.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) PXA PF02194.15 CEH14429.1 - 3.1e-16 59.9 0.1 9.1e-15 55.1 0.0 2.9 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.12 CEH14429.1 - 4e-11 43.5 0.1 5.7e-10 39.8 0.0 2.9 3 0 0 3 3 3 1 Sorting nexin C terminal DHHA2 PF02833.14 CEH14432.1 - 1.2e-15 57.9 0.1 2.1e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CEH14432.1 - 3.2e-08 33.7 0.0 7.4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 DHH family Bac_rhodopsin PF01036.18 CEH14433.1 - 5.4e-47 160.2 17.7 6.9e-47 159.9 17.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein SUR7 PF06687.12 CEH14433.1 - 0.2 11.3 5.4 1.5 8.4 3.5 2.4 2 1 0 2 2 2 0 SUR7/PalI family COX7a PF02238.15 CEH14433.1 - 4.1 7.9 5.8 4 7.9 0.1 3.2 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII DHHC PF01529.20 CEH14434.1 - 1.5e-34 118.9 3.1 1.5e-34 118.9 3.1 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase CrgA PF06781.12 CEH14434.1 - 0.17 12.0 1.0 0.62 10.2 0.1 2.2 2 0 0 2 2 2 0 Cell division protein CrgA CBS PF00571.28 CEH14435.1 - 1e-26 93.2 10.3 7.7e-07 29.5 0.1 5.7 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 CEH14435.1 - 1.7e-05 24.6 0.0 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain DUF4604 PF15377.6 CEH14435.1 - 0.0034 17.8 2.3 0.0034 17.8 2.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) NYN PF01936.18 CEH14435.1 - 0.035 14.6 0.0 0.073 13.6 0.0 1.5 1 0 0 1 1 1 0 NYN domain Ribosomal_S27e PF01667.17 CEH14436.1 - 2e-29 101.1 3.7 2.4e-29 100.8 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 CEH14436.1 - 0.068 12.7 0.6 0.096 12.2 0.6 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_12 PF11331.8 CEH14436.1 - 0.13 12.1 3.4 0.62 9.9 2.5 2.3 1 1 1 2 2 2 0 Probable zinc-ribbon domain zinc_ribbon_4 PF13717.6 CEH14436.1 - 0.14 12.1 1.5 2.3 8.2 1.5 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zf-CSL PF05207.13 CEH14436.1 - 0.17 11.6 2.2 0.42 10.4 2.2 1.7 1 1 0 1 1 1 0 CSL zinc finger Brix PF04427.18 CEH14437.1 - 1.5e-36 126.4 0.0 1.9e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain Ribosomal_L17 PF01196.19 CEH14438.1 - 1.5e-34 118.8 0.0 1.6e-25 89.8 0.0 2.6 1 1 1 2 2 2 2 Ribosomal protein L17 DUF1769 PF08588.10 CEH14439.1 - 1.1e-23 83.2 0.2 2.6e-23 82.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) DSPc PF00782.20 CEH14440.1 - 5.6e-26 90.9 0.0 3.3e-18 65.8 0.0 3.2 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEH14440.1 - 0.00093 18.8 0.0 0.013 15.1 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CEH14440.1 - 0.02 15.0 0.0 0.054 13.6 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate Glyco_hydro_72 PF03198.14 CEH14441.1 - 6.4e-88 295.0 0.0 8.9e-88 294.6 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CEH14441.1 - 2e-13 50.8 0.8 4e-13 49.9 0.8 1.6 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 CEH14441.1 - 7.1e-05 22.4 0.1 0.00021 20.8 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chlam_PMP PF02415.17 CEH14441.1 - 0.0017 18.7 2.8 0.016 15.7 2.8 2.8 1 0 0 1 1 1 1 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Glucan_synthase PF02364.15 CEH14442.1 - 0 1309.2 0.0 0 1308.7 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CEH14442.1 - 8.1e-41 139.4 0.0 2.1e-40 138.0 0.0 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 UCH PF00443.29 CEH14446.1 - 1.2e-47 162.6 0.0 1.7e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEH14446.1 - 2.7e-27 96.2 0.3 5.7e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CEH14446.1 - 0.22 11.0 1.5 0.84 9.1 1.9 1.7 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase SNARE PF05739.19 CEH14447.1 - 1.7e-11 43.9 0.3 4.7e-11 42.5 0.3 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CEH14447.1 - 0.00013 21.8 18.2 0.00037 20.2 15.5 2.6 2 1 0 2 2 2 1 Syntaxin Prominin PF05478.11 CEH14447.1 - 0.07 11.1 4.0 0.15 10.0 4.0 1.7 1 1 0 1 1 1 0 Prominin NPFF PF15085.6 CEH14447.1 - 0.92 9.9 6.6 0.13 12.6 0.4 2.5 3 0 0 3 3 3 0 Neuropeptide FF Epimerase PF01370.21 CEH14448.1 - 1.9e-05 24.3 0.0 0.0005 19.6 0.0 2.5 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CEH14448.1 - 0.023 14.6 0.0 0.38 10.6 0.0 2.6 2 1 0 2 2 2 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 CEH14448.1 - 0.025 13.7 0.0 0.088 11.9 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 CEH14448.1 - 0.035 13.1 0.0 0.33 9.9 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CEH14448.1 - 0.09 11.9 0.0 1.8 7.7 0.0 2.7 3 0 0 3 3 3 0 Male sterility protein GDP_Man_Dehyd PF16363.5 CEH14448.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NDUFA12 PF05071.16 CEH14449.1 - 3.8e-27 94.9 1.5 4.7e-27 94.7 1.5 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Myb_DNA-binding PF00249.31 CEH14450.1 - 1.9e-09 37.6 0.0 0.0014 18.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEH14450.1 - 0.049 13.5 0.3 0.44 10.5 0.0 2.5 2 0 0 2 2 2 0 Myb DNA-binding like DUF4089 PF13318.6 CEH14450.1 - 2.6 8.6 5.3 1.2 9.6 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) Pkinase PF00069.25 CEH14451.1 - 0.0002 20.8 0.0 0.00042 19.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CEH14451.1 - 0.00026 20.4 0.1 0.00056 19.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH14451.1 - 0.0003 20.8 0.1 0.0022 18.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Sugar_tr PF00083.24 CEH14452.1 - 3.7e-126 421.6 19.2 4.6e-126 421.3 19.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH14452.1 - 3.4e-23 82.1 32.5 3.2e-18 65.8 7.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OPT PF03169.15 CEH14454.1 - 1.8e-117 393.6 34.5 3.9e-117 392.4 34.5 1.5 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Reticulon PF02453.17 CEH14454.1 - 0.017 15.1 2.2 0.068 13.1 2.2 2.0 1 0 0 1 1 1 0 Reticulon 4HBT PF03061.22 CEH14455.1 - 1.7e-08 34.7 0.0 3.3e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 CEH14455.1 - 6.4e-08 33.1 0.0 8.8e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 CEH14455.1 - 7.1e-05 22.2 0.5 0.018 14.3 0.3 2.2 2 0 0 2 2 2 2 Acyl-ACP thioesterase MFS_1 PF07690.16 CEH14457.1 - 3.9e-07 29.3 17.8 3.9e-07 29.3 17.8 3.5 2 2 0 2 2 2 1 Major Facilitator Superfamily NUDIX PF00293.28 CEH14458.1 - 2.1e-10 40.7 0.0 3.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain OxoDH_E1alpha_N PF12573.8 CEH14458.1 - 0.016 15.0 0.5 0.043 13.6 0.5 1.8 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal adh_short_C2 PF13561.6 CEH14459.1 - 1.1e-45 156.0 0.0 6.1e-24 84.9 0.0 3.0 3 0 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH14459.1 - 7.8e-43 146.2 0.0 5.9e-17 61.8 0.0 3.1 3 0 0 3 3 3 3 short chain dehydrogenase KR PF08659.10 CEH14459.1 - 2.2e-07 31.0 0.1 2e-05 24.6 0.0 2.4 2 1 0 2 2 2 2 KR domain RICTOR_N PF14664.6 CEH14460.1 - 2.5e-85 286.7 0.0 4.7e-85 285.8 0.0 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 CEH14460.1 - 4.1e-33 113.3 0.1 1e-30 105.6 0.1 4.3 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 CEH14460.1 - 4.2e-31 107.5 0.2 4.8e-29 100.9 0.0 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 CEH14460.1 - 1.2e-29 102.4 0.2 7.3e-27 93.4 0.1 3.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 CEH14460.1 - 4.1e-12 46.0 0.0 2e-11 43.8 0.0 2.3 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.22 CEH14460.1 - 0.00015 21.7 3.2 0.11 12.8 0.1 5.2 4 0 0 4 4 4 1 HEAT repeat Uds1 PF15456.6 CEH14460.1 - 0.0015 18.7 5.0 0.0021 18.2 0.0 3.4 3 0 0 3 3 3 1 Up-regulated During Septation HEAT_EZ PF13513.6 CEH14460.1 - 0.055 14.0 7.8 14 6.3 0.0 5.9 5 1 0 5 5 5 0 HEAT-like repeat ABC_tran_CTD PF16326.5 CEH14460.1 - 0.18 12.1 1.0 0.39 11.0 0.1 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain ABC_membrane PF00664.23 CEH14461.1 - 6.4e-47 160.5 4.3 8.2e-47 160.1 4.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CEH14461.1 - 1.1e-32 113.4 0.0 3.3e-32 111.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 CEH14461.1 - 0.00032 21.1 1.7 0.0055 17.1 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 CEH14461.1 - 0.0037 16.7 0.0 0.021 14.2 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CEH14461.1 - 0.0059 15.5 0.0 0.0098 14.7 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class Glu-tRNAGln PF02686.15 CEH14461.1 - 0.028 14.7 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Zeta_toxin PF06414.12 CEH14461.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin UDPGP PF01704.18 CEH14462.1 - 1.1e-43 149.5 0.0 1.4e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CEH14462.1 - 0.0016 18.8 0.3 0.0068 16.8 0.0 2.2 3 0 0 3 3 3 1 MobA-like NTP transferase domain ORC5_C PF14630.6 CEH14463.1 - 3.1e-54 184.4 1.4 3.8e-54 184.1 1.4 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Nop14 PF04147.12 CEH14464.1 - 0.00011 20.7 8.5 0.00011 20.7 8.5 1.6 2 0 0 2 2 2 1 Nop14-like family SDA1 PF05285.12 CEH14464.1 - 0.011 15.2 17.2 0.015 14.7 17.2 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 CEH14464.1 - 0.12 11.0 14.1 0.16 10.5 14.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SpoIIIAH PF12685.7 CEH14464.1 - 0.25 11.1 5.5 0.39 10.5 5.5 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 CEH14464.1 - 0.5 8.6 13.5 0.69 8.1 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 CEH14464.1 - 2 7.9 15.4 3.2 7.3 15.4 1.2 1 0 0 1 1 1 0 PPP4R2 SURF2 PF05477.11 CEH14464.1 - 3 7.5 11.9 4.4 6.9 11.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NOA36 PF06524.12 CEH14464.1 - 5.2 6.3 20.6 8.2 5.7 20.6 1.3 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 CEH14464.1 - 6 6.8 6.8 11 5.9 6.8 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RR_TM4-6 PF06459.12 CEH14464.1 - 7.1 6.4 8.2 10 5.8 8.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DNA_pol_phi PF04931.13 CEH14464.1 - 8.3 4.4 22.9 13 3.7 22.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Spore_coat_CotO PF14153.6 CEH14464.1 - 9.2 6.2 7.5 14 5.6 7.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Pkinase PF00069.25 CEH14465.1 - 3.4e-74 249.5 0.0 4e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH14465.1 - 4.4e-36 124.5 0.0 6e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEH14465.1 - 0.00056 19.0 0.0 0.012 14.6 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CEH14465.1 - 0.0078 15.6 0.1 0.024 13.9 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 CEH14465.1 - 0.015 15.2 0.0 0.11 12.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CEH14465.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 CEH14465.1 - 0.15 11.3 0.3 0.39 10.0 0.3 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CDP-OH_P_transf PF01066.21 CEH14467.1 - 5.1e-14 52.8 0.4 5.1e-14 52.8 0.4 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Trehalase PF01204.18 CEH14468.1 - 2.9e-171 570.8 3.9 3.6e-171 570.4 3.9 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CEH14468.1 - 1.6e-16 59.7 0.2 3e-16 58.8 0.2 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain CAP PF00188.26 CEH14468.1 - 0.053 14.4 0.5 0.15 12.9 0.0 1.9 2 0 0 2 2 2 0 Cysteine-rich secretory protein family Metallophos PF00149.28 CEH14469.1 - 5.1e-10 40.2 0.0 2.7e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2464 PF10240.9 CEH14469.1 - 0.098 12.2 0.0 9.7 5.7 0.0 2.3 2 0 0 2 2 2 0 Multivesicular body subunit 12 DUF4112 PF13430.6 CEH14470.1 - 1.9e-27 95.6 0.9 2.5e-27 95.2 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) MIT PF04212.18 CEH14471.1 - 5e-08 32.9 0.2 1.1e-07 31.8 0.2 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain GST_N_3 PF13417.6 CEH14472.1 - 2.4e-17 63.1 0.0 4.8e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEH14472.1 - 1e-14 54.6 0.0 2.1e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEH14472.1 - 5.3e-09 36.3 0.1 8.5e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEH14472.1 - 0.009 16.0 0.1 0.022 14.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 CEH14472.1 - 0.014 15.9 0.0 0.036 14.6 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DNA_pol_B_thumb PF14791.6 CEH14473.1 - 4.5e-09 36.4 0.0 0.00085 19.4 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase beta thumb Syndecan PF01034.20 CEH14474.1 - 0.023 14.6 1.0 0.038 13.9 1.0 1.3 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 CEH14474.1 - 0.025 15.4 0.0 0.048 14.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 CEH14474.1 - 0.029 14.6 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4538 PF15061.6 CEH14474.1 - 0.047 13.4 0.1 0.081 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) CcmD PF04995.14 CEH14474.1 - 0.17 12.0 0.9 0.35 11.0 0.9 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2207 PF09972.9 CEH14474.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FeoB_associated PF12669.7 CEH14474.1 - 0.21 12.0 1.5 0.41 11.1 1.5 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein zf-C3HC4_3 PF13920.6 CEH14475.1 - 5.7e-08 32.5 8.5 1.6e-07 31.0 8.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEH14475.1 - 1.1e-06 28.4 5.4 1.9e-06 27.7 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEH14475.1 - 0.00032 21.0 6.3 0.00065 20.0 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CEH14475.1 - 0.0013 18.6 4.5 0.0023 17.9 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEH14475.1 - 0.0019 18.2 3.9 0.0025 17.8 2.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEH14475.1 - 0.013 15.4 6.8 0.13 12.1 6.8 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-H2C2_2 PF13465.6 CEH14475.1 - 0.13 12.7 0.1 0.26 11.8 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double domain zf-RING_4 PF14570.6 CEH14475.1 - 0.69 9.8 4.4 1.6 8.6 4.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CEH14475.1 - 1.4 8.8 8.9 0.065 13.1 2.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) XRN_M PF17846.1 CEH14476.1 - 2e-144 481.8 0.2 1.1e-104 350.9 0.0 2.4 3 0 0 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 CEH14476.1 - 5.5e-101 337.0 1.0 8.5e-101 336.4 0.0 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 CEH14476.1 - 0.0042 17.1 6.4 0.0074 16.3 6.4 1.4 1 0 0 1 1 1 1 Zinc knuckle ATP-synt_DE_N PF02823.16 CEH14477.1 - 2.2e-17 62.7 0.0 3.1e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Glyco_transf_28 PF03033.20 CEH14478.1 - 2.5e-28 98.9 0.0 4.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 CEH14478.1 - 1.2e-20 73.5 0.0 9.9e-14 51.2 0.0 3.2 3 0 0 3 3 3 2 GRAM domain PH PF00169.29 CEH14478.1 - 7.6e-07 29.6 0.0 4.2e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 CEH14478.1 - 0.00058 18.8 0.0 0.00091 18.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 CEH14478.1 - 0.00098 19.5 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_12 PF16457.5 CEH14478.1 - 0.05 14.1 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain TruD PF01142.18 CEH14479.1 - 7.3e-54 183.2 0.0 7.1e-42 143.7 0.0 4.5 4 2 0 4 4 4 4 tRNA pseudouridine synthase D (TruD) LSM PF01423.22 CEH14482.1 - 8.9e-17 60.5 0.1 1.1e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain ATP-synt_G PF04718.15 CEH14484.1 - 2.2e-17 63.7 1.0 6e-17 62.3 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Chlorosome_CsmC PF11098.8 CEH14484.1 - 0.11 12.5 1.8 0.24 11.4 1.8 1.6 1 0 0 1 1 1 0 Chlorosome envelope protein C Abhydrolase_6 PF12697.7 CEH14485.1 - 0.0012 19.5 2.0 0.0012 19.5 2.0 3.1 2 1 1 3 3 3 1 Alpha/beta hydrolase family Pkinase PF00069.25 CEH14486.1 - 1.3e-50 172.3 0.0 2e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH14486.1 - 8.2e-20 71.2 0.0 1.7e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEH14486.1 - 0.0084 16.1 0.1 0.0084 16.1 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CEH14486.1 - 0.081 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family zf-CCHC PF00098.23 CEH14487.1 - 2.6e-15 55.7 19.4 7.6e-05 22.6 2.9 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 CEH14487.1 - 8.7e-09 35.0 15.1 0.0011 18.7 0.0 4.2 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 CEH14487.1 - 0.00087 19.0 16.6 0.065 13.0 0.2 4.2 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.6 CEH14487.1 - 3.6 7.6 15.1 3.7 7.6 0.5 4.4 3 1 1 4 4 4 0 Zinc knuckle EF_TS PF00889.19 CEH14488.1 - 9.7e-11 41.7 0.0 4.9e-10 39.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor TS Y_phosphatase2 PF03162.13 CEH14489.1 - 5.5e-22 78.1 0.0 3.4e-21 75.5 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family DinB PF05163.12 CEH14490.1 - 0.0018 18.2 0.2 0.0047 16.9 0.2 1.6 1 0 0 1 1 1 1 DinB family VPS9 PF02204.18 CEH14490.1 - 0.021 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain Apolipoprotein PF01442.18 CEH14490.1 - 4.5 7.1 13.6 3.1 7.6 4.9 3.6 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain Sugar_tr PF00083.24 CEH14491.1 - 1.7e-57 195.3 6.8 3.3e-57 194.3 6.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH14491.1 - 3.5e-20 72.3 26.3 3.5e-20 72.3 26.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_16 PF10294.9 CEH14492.1 - 2.4e-21 76.2 0.0 1e-13 51.4 0.0 3.0 2 1 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 CEH14492.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Actin PF00022.19 CEH14493.1 - 5.2e-88 295.4 0.0 8.2e-87 291.4 0.0 1.9 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CEH14493.1 - 0.0041 17.5 0.0 0.19 12.2 0.0 2.8 2 1 0 2 2 2 1 Cell division protein FtsA CRC_subunit PF08624.10 CEH14494.1 - 2.3e-40 138.2 0.0 4.3e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit HlyD_D23 PF16576.5 CEH14494.1 - 0.001 18.3 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Abhydrolase_6 PF12697.7 CEH14495.1 - 0.0038 17.9 0.0 0.0073 16.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Carn_acyltransf PF00755.20 CEH14497.1 - 1.1e-159 532.9 0.0 1.2e-159 532.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CGI-121 PF08617.10 CEH14498.1 - 7.4e-34 117.2 0.0 9.1e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 MFS_1 PF07690.16 CEH14500.1 - 3.8e-21 75.4 42.6 1.7e-13 50.2 18.1 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Defensin_propep PF00879.18 CEH14500.1 - 0.11 12.7 0.8 1.7 9.0 1.9 2.3 2 0 0 2 2 2 0 Defensin propeptide DUF543 PF04418.12 CEH14500.1 - 0.12 12.3 1.2 0.62 10.1 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) OATP PF03137.20 CEH14500.1 - 0.26 9.5 12.6 0.018 13.4 3.3 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MS_channel PF00924.18 CEH14501.1 - 5.4e-17 62.0 0.3 9.7e-17 61.2 0.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 CEH14501.1 - 0.014 14.9 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 CEH14501.1 - 0.072 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 CEH14501.1 - 0.086 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain NAD_binding_4 PF07993.12 CEH14502.1 - 3e-12 46.3 0.2 4.6e-09 35.8 0.1 3.0 2 1 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 CEH14502.1 - 9.2e-10 38.4 0.2 3e-09 36.7 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEH14502.1 - 6.1e-09 35.3 0.0 1.9e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CEH14502.1 - 8.3e-05 22.1 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CEH14502.1 - 0.00017 21.5 0.1 0.00031 20.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DEDD_Tnp_IS110 PF01548.17 CEH14502.1 - 0.054 13.4 0.6 0.085 12.7 0.6 1.3 1 0 0 1 1 1 0 Transposase LCAT PF02450.15 CEH14502.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase F-box-like PF12937.7 CEH14503.1 - 0.087 12.7 0.1 0.29 11.1 0.1 1.9 2 0 0 2 2 2 0 F-box-like Ig_mannosidase PF17753.1 CEH14504.1 - 3.7e-21 74.7 0.0 9.4e-21 73.4 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 CEH14504.1 - 3.4e-07 30.8 0.2 1e-06 29.2 0.1 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 CEH14504.1 - 0.00064 20.4 0.0 0.0018 18.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF1897 PF09005.10 CEH14504.1 - 0.12 11.9 2.7 0.28 10.7 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) Sugar_tr PF00083.24 CEH14505.1 - 4.5e-82 276.3 16.9 6e-82 275.9 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH14505.1 - 4.5e-14 52.2 25.6 6.5e-14 51.6 25.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OrfB_Zn_ribbon PF07282.11 CEH14506.1 - 0.035 14.0 0.2 0.095 12.6 0.2 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 CEH14506.1 - 0.072 13.2 0.9 16 5.7 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 CEH14506.1 - 0.21 11.1 0.1 0.48 10.0 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Acetyltransf_1 PF00583.25 CEH14507.1 - 1.2e-11 44.9 0.0 1.8e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEH14507.1 - 2.8e-05 24.1 0.0 3.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEH14507.1 - 3.9e-05 24.0 0.0 7.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEH14507.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 CEH14507.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Mpv17_PMP22 PF04117.12 CEH14508.1 - 8e-25 86.8 0.8 1.3e-24 86.1 0.8 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family UXS1_N PF11803.8 CEH14508.1 - 0.069 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal DFRP_C PF16543.5 CEH14510.1 - 8.4e-19 67.9 6.7 8.4e-19 67.9 6.7 3.6 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_3 PF15663.5 CEH14510.1 - 8e-06 26.0 0.8 0.0044 17.2 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 CEH14510.1 - 0.11 12.3 10.9 9.4 6.2 0.3 4.3 4 0 0 4 4 4 0 CCCH-type zinc finger Torus PF16131.5 CEH14510.1 - 1.9 9.2 21.1 12 6.6 0.4 4.1 2 1 1 3 3 3 0 Torus domain zf_CCCH_4 PF18345.1 CEH14510.1 - 3.2 8.0 15.6 10 6.3 4.8 4.0 3 1 0 3 3 3 0 Zinc finger domain PWWP PF00855.17 CEH14511.1 - 1.2e-17 64.1 0.2 1.2e-17 64.1 0.2 2.1 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 CEH14511.1 - 2.1e-05 24.5 0.0 4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CDC45 PF02724.14 CEH14511.1 - 8.9 4.5 11.5 10 4.3 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Lipase_3 PF01764.25 CEH14512.1 - 3.1e-12 46.6 0.0 6.8e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Sugar_tr PF00083.24 CEH14513.1 - 2.5e-111 372.8 20.9 3.1e-111 372.4 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH14513.1 - 2e-13 50.0 11.5 2e-13 50.0 11.5 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CEH14513.1 - 0.00011 20.7 2.7 0.00011 20.7 2.7 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TPR_19 PF14559.6 CEH14513.1 - 0.0023 18.4 0.0 0.0059 17.1 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Rx_N PF18052.1 CEH14513.1 - 0.051 13.9 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 Rx N-terminal domain PALB2_WD40 PF16756.5 CEH14514.1 - 0.014 14.3 0.0 0.018 14.0 0.0 1.0 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain DAHP_synth_1 PF00793.20 CEH14515.1 - 8.9e-94 313.4 0.0 1.7e-93 312.5 0.0 1.5 1 0 0 1 1 1 1 DAHP synthetase I family Aldedh PF00171.22 CEH14515.1 - 1.1e-14 53.8 0.1 1.2e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 CEH14517.1 - 3.8e-22 78.7 37.4 2.5e-18 66.2 11.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH14517.1 - 0.00045 19.2 9.1 0.00045 19.2 9.1 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2370 PF10176.9 CEH14517.1 - 0.27 10.8 0.5 0.59 9.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) YL1 PF05764.13 CEH14517.1 - 1.2 9.2 5.2 0.29 11.2 1.5 1.8 2 0 0 2 2 2 0 YL1 nuclear protein GMC_oxred_N PF00732.19 CEH14518.1 - 2e-59 201.4 0.0 2.9e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEH14518.1 - 6.6e-32 111.0 0.2 1.3e-31 110.0 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CEH14518.1 - 2.9e-05 23.3 0.7 0.029 13.4 0.5 2.4 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 CEH14518.1 - 0.0013 17.9 0.1 0.0022 17.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 CEH14518.1 - 0.0015 17.8 0.1 0.0035 16.6 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 CEH14518.1 - 0.0032 17.7 1.5 0.0063 16.7 0.6 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CEH14518.1 - 0.029 13.1 1.0 0.46 9.1 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 CEH14518.1 - 0.036 13.3 0.1 0.84 8.8 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEH14518.1 - 0.038 13.2 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEH14518.1 - 0.12 12.0 6.6 0.41 10.2 5.4 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 CEH14518.1 - 0.12 12.6 0.2 0.63 10.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Gar1 PF04410.14 CEH14521.1 - 6.6e-32 110.4 0.0 7.8e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Fip1 PF05182.13 CEH14522.1 - 7.1e-17 60.6 2.3 1.3e-16 59.8 2.3 1.4 1 0 0 1 1 1 1 Fip1 motif YlbD_coat PF14071.6 CEH14522.1 - 1.6 9.0 4.8 0.71 10.1 0.1 2.5 2 0 0 2 2 2 0 Putative coat protein Dickkopf_N PF04706.12 CEH14523.1 - 0.4 11.2 20.1 1.4 9.5 10.2 3.7 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Pkinase PF00069.25 CEH14524.1 - 4.4e-66 222.9 0.0 6.4e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH14524.1 - 1.4e-33 116.3 0.0 2e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH14524.1 - 1.5e-09 37.6 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEH14524.1 - 0.00093 18.6 0.2 0.0017 17.7 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEH14524.1 - 0.00094 18.1 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEH14524.1 - 0.00096 19.1 0.7 0.0021 18.0 0.7 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEH14524.1 - 0.0011 18.0 0.1 0.0019 17.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CEH14524.1 - 0.084 12.5 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 RIO1 family LAG1-DNAbind PF09271.11 CEH14525.1 - 2.7e-43 148.2 0.4 5.9e-43 147.1 0.0 1.9 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 CEH14525.1 - 5.2e-17 62.5 0.0 4e-16 59.6 0.0 2.4 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain TIG PF01833.24 CEH14525.1 - 0.004 17.2 0.1 0.013 15.6 0.1 1.9 1 0 0 1 1 1 1 IPT/TIG domain AAA_9 PF12781.7 CEH14527.1 - 1.5e-70 236.8 0.1 1.5e-70 236.8 0.1 2.9 3 0 0 3 3 3 1 ATP-binding dynein motor region MT PF12777.7 CEH14527.1 - 5.6e-43 147.3 8.2 9.3e-43 146.6 8.2 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 CEH14527.1 - 5.2e-39 134.3 0.0 1e-38 133.3 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CEH14527.1 - 7e-33 113.8 0.0 1.4e-32 112.8 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CEH14527.1 - 5.2e-28 97.5 0.0 2.6e-27 95.2 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 CEH14527.1 - 8.9e-05 21.9 0.0 0.0002 20.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 CENP-H PF05837.12 CEH14527.1 - 0.014 15.8 3.1 0.014 15.8 3.1 4.8 4 1 1 5 5 5 0 Centromere protein H (CENP-H) DASH_Duo1 PF08651.10 CEH14527.1 - 0.99 9.2 3.8 9.7 6.1 0.0 3.3 3 0 0 3 3 3 0 DASH complex subunit Duo1 Phage_GP20 PF06810.11 CEH14527.1 - 5 6.9 19.8 5.1 6.9 0.0 3.6 3 1 0 3 3 3 0 Phage minor structural protein GP20 ERM PF00769.19 CEH14527.1 - 6.7 6.4 36.3 0.016 15.0 13.0 3.2 3 1 0 3 3 3 0 Ezrin/radixin/moesin family DUF5082 PF16888.5 CEH14528.1 - 0.45 10.8 12.7 0.068 13.5 1.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Prominin PF05478.11 CEH14528.1 - 3.4 5.5 11.8 0.39 8.6 3.5 2.1 2 0 0 2 2 2 0 Prominin UPF0449 PF15136.6 CEH14528.1 - 5.4 7.5 9.2 4.6 7.8 3.1 3.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 PQ-loop PF04193.14 CEH14529.1 - 5.1e-27 93.4 4.4 3.1e-12 46.1 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat NAD_binding_8 PF13450.6 CEH14530.1 - 1.4e-12 47.7 0.0 4.1e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CEH14530.1 - 0.0002 20.8 0.0 0.0012 18.2 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 CEH14530.1 - 0.00084 19.4 0.3 0.0064 16.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 CEH14530.1 - 0.023 13.9 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 CEH14530.1 - 0.03 14.9 0.0 0.08 13.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 CEH14530.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 MCRA family Cyclin_N PF00134.23 CEH14531.1 - 1.3e-05 25.0 0.1 0.00014 21.6 0.1 2.1 1 1 0 1 1 1 1 Cyclin, N-terminal domain DUF1744 PF08490.12 CEH14532.1 - 7.6e-126 419.9 0.0 1.4e-125 419.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CEH14532.1 - 5.8e-77 259.1 0.0 8.5e-77 258.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CEH14532.1 - 6.6e-13 48.2 0.1 1.7e-11 43.5 0.0 2.7 2 2 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CEH14532.1 - 6.6e-10 39.0 0.2 1.9e-09 37.6 0.2 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CEH14532.1 - 3.3e-05 23.9 0.1 0.00015 21.8 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily Hexokinase_2 PF03727.16 CEH14533.1 - 2.7e-76 256.2 0.0 3.5e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEH14533.1 - 4.3e-72 242.2 0.0 5.9e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase ATP-synt_I PF03899.15 CEH14533.1 - 0.076 13.4 0.1 7.4 7.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase I chain Gly-zipper_Omp PF13488.6 CEH14533.1 - 0.45 10.6 4.0 1.6 8.8 1.3 2.5 2 0 0 2 2 2 0 Glycine zipper RRP7 PF12923.7 CEH14534.1 - 1.9e-28 99.0 1.9 2.7e-28 98.5 0.5 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 CEH14534.1 - 1.3e-05 25.0 0.0 0.00012 21.9 0.0 2.3 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 CEH14534.1 - 4.1e-05 23.3 0.0 0.00081 19.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L30_N PF08079.12 CEH14535.1 - 1.2e-25 89.5 17.1 1.2e-25 89.5 17.1 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CEH14535.1 - 6.4e-16 58.0 1.1 6.4e-16 58.0 1.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PGBA_C PF15437.6 CEH14535.1 - 0.22 11.9 10.5 0.36 11.2 10.5 1.3 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal VSG_B PF13206.6 CEH14535.1 - 1.3 8.2 5.7 1.8 7.7 5.7 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF5427 PF10310.9 CEH14536.1 - 2.4e-27 96.1 2.0 1.2e-25 90.4 0.1 2.9 1 1 1 2 2 2 2 Family of unknown function (DUF5427) CLTH PF10607.9 CEH14537.1 - 2.3e-29 102.2 0.0 3.2e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CEH14537.1 - 1.6e-08 34.2 0.4 4e-08 32.9 0.2 1.8 2 0 0 2 2 2 1 LisH Methyltransf_16 PF10294.9 CEH14538.1 - 4.1e-13 49.4 0.0 9e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 CEH14538.1 - 0.00067 20.4 0.0 0.0018 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH14538.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH14538.1 - 0.0063 17.2 0.0 0.022 15.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 CEH14538.1 - 0.079 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 CEH14538.1 - 0.13 12.1 0.0 0.36 10.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CEH14538.1 - 0.22 11.3 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ODC_AZ PF02100.17 CEH14539.1 - 3.2e-09 36.8 0.0 5.5e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme UQ_con PF00179.26 CEH14540.1 - 1e-52 177.5 0.0 1.2e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEH14540.1 - 0.0026 17.5 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CEH14540.1 - 0.0027 18.0 0.0 0.0032 17.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 CEH14540.1 - 0.044 13.6 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Molydop_binding PF01568.21 CEH14541.1 - 0.11 12.5 0.1 0.42 10.6 0.1 2.0 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain MFS_1 PF07690.16 CEH14542.1 - 2.1e-38 132.2 43.4 8.3e-37 126.9 42.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH14542.1 - 4.7e-12 45.5 9.3 4.7e-12 45.5 9.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CEH14542.1 - 1e-09 37.4 11.4 2.2e-09 36.3 10.9 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3948 PF13134.6 CEH14542.1 - 0.15 11.8 3.8 0.44 10.3 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Glyco_transf_24 PF18404.1 CEH14543.1 - 2.3e-138 460.1 2.2 3.2e-138 459.6 2.2 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CEH14543.1 - 3.5e-51 174.6 0.0 3.6e-49 168.0 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 CEH14543.1 - 5.4e-40 137.3 0.1 2.1e-39 135.4 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 CEH14543.1 - 9.7e-37 127.0 0.0 2.5e-35 122.4 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CEH14543.1 - 1.7e-33 115.0 0.0 3.3e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 CEH14543.1 - 8.1e-27 93.8 0.0 1.9e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 CEH14543.1 - 4.2e-06 26.5 0.2 7.1e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DIL PF01843.19 CEH14545.1 - 2.2e-27 95.4 2.7 4.9e-27 94.2 2.7 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 CEH14545.1 - 3.3e-11 43.6 0.0 8.3e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEH14545.1 - 4.7e-11 43.0 0.0 8.7e-05 23.0 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEH14545.1 - 2.2e-09 36.8 0.0 0.00021 21.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CEH14545.1 - 3.5e-09 36.7 0.0 0.00018 21.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CEH14545.1 - 4.8e-08 33.1 0.1 0.00028 21.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) MRP-S27 PF10037.9 CEH14545.1 - 0.03 13.2 2.8 0.049 12.5 2.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF883 PF05957.13 CEH14547.1 - 0.0024 18.5 2.9 0.0024 18.5 2.9 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.8 CEH14547.1 - 0.011 15.0 5.2 0.015 14.6 5.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Borrelia_P83 PF05262.11 CEH14547.1 - 0.036 12.6 5.0 0.045 12.2 5.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CRISPR_Cse1 PF09481.10 CEH14547.1 - 0.039 13.1 1.7 0.045 12.8 1.7 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) Pex26 PF07163.12 CEH14547.1 - 0.12 11.7 1.4 0.16 11.2 1.4 1.1 1 0 0 1 1 1 0 Pex26 protein DUF4230 PF14014.6 CEH14547.1 - 0.15 12.3 1.8 0.2 11.9 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) TMPIT PF07851.13 CEH14547.1 - 0.17 11.1 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein GARP PF16731.5 CEH14547.1 - 0.42 10.3 14.5 0.088 12.5 11.0 1.5 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma YdfA_immunity PF12127.8 CEH14547.1 - 0.72 8.9 6.3 0.61 9.1 5.2 1.4 2 0 0 2 2 2 0 SigmaW regulon antibacterial ATP-synt_B PF00430.18 CEH14547.1 - 1.1 9.3 14.5 2 8.5 14.5 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) UcrQ PF02939.16 CEH14548.1 - 7.6e-30 102.7 0.8 8.8e-30 102.5 0.8 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 CEH14548.1 - 0.061 13.7 0.2 0.1 13.0 0.2 1.4 1 1 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 NTP_transf_2 PF01909.23 CEH14549.1 - 0.012 15.8 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain OAS1_C PF10421.9 CEH14549.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus SPT2 PF08243.11 CEH14550.1 - 6.6e-16 58.8 26.7 6.6e-16 58.8 26.7 4.9 4 2 1 5 5 5 1 SPT2 chromatin protein Cyclophil_like PF04126.13 CEH14551.1 - 0.13 12.1 0.1 0.19 11.5 0.1 1.3 1 1 0 1 1 1 0 Cyclophilin-like p450 PF00067.22 CEH14552.1 - 2.3e-34 118.9 0.0 3.3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Syntaxin-6_N PF09177.11 CEH14555.1 - 9.1e-19 67.9 1.9 1.9e-18 66.9 0.2 2.0 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 CEH14555.1 - 2.7e-06 27.3 0.1 7.1e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 CEH14555.1 - 6.2e-05 22.8 0.4 0.00028 20.7 0.0 2.0 2 1 0 2 2 2 1 Membrane fusion protein Use1 DUF3584 PF12128.8 CEH14555.1 - 0.0019 15.8 4.4 0.0028 15.3 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HisKA_3 PF07730.13 CEH14555.1 - 0.017 15.7 3.5 1.9 9.0 0.3 2.6 2 0 0 2 2 2 0 Histidine kinase Fez1 PF06818.15 CEH14555.1 - 0.22 12.0 4.0 0.88 10.0 4.0 1.9 1 1 0 1 1 1 0 Fez1 PspA_IM30 PF04012.12 CEH14555.1 - 0.23 11.0 4.1 4.1 6.9 2.6 2.2 1 1 1 2 2 2 0 PspA/IM30 family DUF16 PF01519.16 CEH14555.1 - 0.42 11.1 1.8 2 9.0 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 ATG16 PF08614.11 CEH14555.1 - 1.4 9.1 6.7 7.5 6.7 1.4 2.2 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 CEH14555.1 - 6.4 6.0 10.5 58 2.9 10.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FKBP_C PF00254.28 CEH14556.1 - 1.8e-34 117.9 0.0 3.2e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Mlh1_C PF16413.5 CEH14557.1 - 4.3e-77 259.1 0.0 6.1e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CEH14557.1 - 1.4e-29 102.2 0.0 2.4e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CEH14557.1 - 7.4e-09 35.5 0.0 1.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CEH14557.1 - 2e-08 34.7 0.0 1.7e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4777 PF16007.5 CEH14557.1 - 0.53 10.6 1.5 26 5.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4777) zf-CCCH PF00642.24 CEH14558.1 - 6.5e-06 25.9 5.3 1.3e-05 25.0 5.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEH14558.1 - 0.48 10.3 3.7 0.79 9.6 3.7 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEH14558.1 - 1.2 9.3 3.8 5.9 7.1 3.8 2.0 1 1 0 1 1 1 0 Zinc finger domain Ferric_reduct PF01794.19 CEH14560.1 - 2.8e-26 92.1 8.5 2.8e-26 92.1 8.5 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEH14560.1 - 4.6e-08 33.3 0.0 9.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEH14560.1 - 3.1e-07 30.4 0.0 6.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain AAA PF00004.29 CEH14561.1 - 1.7e-41 141.8 0.0 3.1e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 CEH14561.1 - 2.3e-21 75.6 7.4 5.2e-21 74.5 7.4 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CEH14561.1 - 5.3e-08 32.5 0.0 1.9e-07 30.8 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain Vps4_C PF09336.10 CEH14561.1 - 3.1e-07 30.3 0.0 1.3e-06 28.3 0.0 2.1 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 CEH14561.1 - 3.2e-06 27.6 0.1 0.00058 20.3 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 CEH14561.1 - 6.2e-05 22.4 0.0 0.00018 20.9 0.0 1.8 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_5 PF07728.14 CEH14561.1 - 7.8e-05 22.7 0.0 0.00023 21.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEH14561.1 - 9.3e-05 22.7 0.1 0.0096 16.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CEH14561.1 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CEH14561.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CEH14561.1 - 0.00067 20.0 0.0 0.019 15.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 CEH14561.1 - 0.0007 19.8 0.0 0.0023 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEH14561.1 - 0.00099 19.1 0.0 0.0041 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CEH14561.1 - 0.002 17.3 0.0 0.0043 16.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 CEH14561.1 - 0.0036 16.9 0.1 0.17 11.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 CEH14561.1 - 0.0044 17.6 0.1 0.014 15.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 CEH14561.1 - 0.0046 17.1 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 CEH14561.1 - 0.016 15.6 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CEH14561.1 - 0.019 14.7 0.1 0.06 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CEH14561.1 - 0.025 14.0 0.0 0.062 12.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CEH14561.1 - 0.041 13.2 0.1 2.9 7.2 0.0 2.6 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.26 CEH14561.1 - 0.056 13.1 0.0 0.42 10.3 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 CEH14561.1 - 0.059 13.3 0.3 2.2 8.1 0.0 2.7 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CEH14561.1 - 0.094 12.6 0.0 0.48 10.3 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_7 PF12775.7 CEH14561.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF4407 PF14362.6 CEH14561.1 - 0.14 11.5 1.3 0.2 11.0 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PhoH PF02562.16 CEH14561.1 - 0.17 11.3 0.1 0.45 9.9 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein RhlB PF12300.8 CEH14561.1 - 0.47 10.6 4.6 0.93 9.6 0.3 2.3 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB VirionAssem_T7 PF11653.8 CEH14562.1 - 0.047 14.2 4.6 0.09 13.3 4.6 1.5 1 1 0 1 1 1 0 Bacteriophage T7 virion assembly protein TPPII_N PF12583.8 CEH14562.1 - 0.21 12.2 9.2 0.29 11.7 9.1 1.3 1 1 0 1 1 1 0 Tripeptidyl peptidase II N terminal BRF1 PF07741.13 CEH14562.1 - 10 6.6 8.5 1.5e+02 2.8 8.5 2.0 1 1 0 1 1 1 0 Brf1-like TBP-binding domain ANAPC1 PF12859.7 CEH14564.1 - 6.1e-10 39.8 1.3 6.1e-10 39.8 1.3 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 Spt4 PF06093.13 CEH14565.1 - 7.7e-26 90.0 0.2 9.1e-26 89.8 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger WD40 PF00400.32 CEH14566.1 - 2.9e-42 141.8 25.6 2.5e-09 37.6 0.4 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH14566.1 - 2.4e-15 56.6 0.0 0.0024 18.1 0.0 6.6 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEH14566.1 - 6.8e-08 31.8 0.2 0.0037 16.3 0.0 4.2 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CEH14566.1 - 0.045 13.7 1.5 2.6 8.1 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat FRG1 PF06229.12 CEH14567.1 - 1.1e-13 51.3 1.6 2.1e-13 50.4 0.0 2.2 2 1 0 2 2 2 1 FRG1-like domain XPG_N PF00752.17 CEH14569.1 - 3e-32 111.1 0.0 5.9e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CEH14569.1 - 6.4e-30 103.4 0.0 1.4e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CEH14569.1 - 8.7e-08 32.7 0.0 2.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Fe_dep_repr_C PF02742.15 CEH14569.1 - 0.016 15.3 0.3 1.4 9.0 0.0 3.0 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain HHH_5 PF14520.6 CEH14569.1 - 0.026 15.1 0.1 0.1 13.2 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain CENP-K PF11802.8 CEH14570.1 - 1.7e-19 70.5 6.4 1.7e-17 63.9 6.4 2.5 1 1 0 1 1 1 1 Centromere-associated protein K Rsd_AlgQ PF04353.13 CEH14570.1 - 0.0075 16.2 0.6 0.016 15.2 0.6 1.6 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Selenoprotein_S PF06936.11 CEH14570.1 - 0.039 13.8 2.9 0.067 13.0 2.9 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) CENP-Q PF13094.6 CEH14570.1 - 0.2 11.8 15.7 0.042 14.1 3.3 3.2 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.12 CEH14570.1 - 0.79 9.8 13.9 19 5.3 8.9 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHR10 PF18595.1 CEH14570.1 - 8.1 6.5 17.5 0.076 13.1 7.0 2.5 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Tubulin_3 PF14881.6 CEH14571.1 - 4.6e-19 68.8 3.1 2.3e-18 66.5 0.7 2.7 2 1 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 CEH14571.1 - 1.4e-05 25.4 0.1 7.7e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 Misato Segment II tubulin-like domain Ten1_2 PF15490.6 CEH14572.1 - 1.3e-13 50.7 0.0 1.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit MFS_1 PF07690.16 CEH14573.1 - 6.4e-44 150.3 28.7 2.6e-43 148.3 26.1 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH14573.1 - 1.5e-09 37.2 12.2 3.3e-09 36.1 1.2 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter BT1 PF03092.16 CEH14573.1 - 0.0022 16.3 0.1 0.37 8.9 0.0 2.4 2 0 0 2 2 2 2 BT1 family TMEM141 PF15110.6 CEH14573.1 - 0.069 13.7 0.2 0.22 12.1 0.2 1.9 1 0 0 1 1 1 0 TMEM141 protein family DUF1295 PF06966.12 CEH14574.1 - 5.9e-05 22.7 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 CEH14574.1 - 0.00083 19.7 0.8 0.0015 18.9 0.2 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CEH14574.1 - 0.0017 18.8 0.0 0.0039 17.5 0.0 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1616 PF07760.11 CEH14574.1 - 0.13 11.6 0.1 0.24 10.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) DUF1129 PF06570.11 CEH14574.1 - 0.51 9.8 2.0 0.35 10.3 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) CPSase_L_D2 PF02786.17 CEH14575.1 - 1.3e-68 230.7 0.0 2.2e-68 229.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CEH14575.1 - 4e-44 149.7 0.0 1.1e-43 148.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEH14575.1 - 9.1e-36 122.2 0.0 1.8e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CEH14575.1 - 5.5e-15 54.9 2.2 1.2e-14 53.9 2.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CEH14575.1 - 3.4e-11 43.1 0.0 6.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 CEH14575.1 - 1.6e-06 27.8 0.7 4.9e-05 23.1 0.3 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp PF02222.22 CEH14575.1 - 5.3e-06 26.1 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 CEH14575.1 - 0.00037 21.2 1.0 1.5 9.5 0.1 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 CEH14575.1 - 0.00056 20.0 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CEH14575.1 - 0.0092 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.9 CEH14575.1 - 0.16 11.9 0.4 0.35 10.8 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_D23 PF16576.5 CEH14575.1 - 0.16 11.1 0.9 4.1 6.6 0.1 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF3512 PF12024.8 CEH14576.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) Hydrolase_4 PF12146.8 CEH14577.1 - 2.9e-11 43.1 0.0 5.8e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH14577.1 - 4.3e-08 33.1 0.1 0.00024 20.8 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH14577.1 - 1.2e-06 29.3 0.1 1.6e-06 28.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 CEH14577.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 CEH14577.1 - 0.12 11.8 0.0 0.75 9.2 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family 2-Hacid_dh_C PF02826.19 CEH14578.1 - 6.2e-40 136.4 0.0 1.3e-28 99.6 0.0 2.2 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEH14578.1 - 2.7e-26 91.8 0.0 3.3e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 CEH14578.1 - 0.033 14.8 0.0 0.12 13.0 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Mito_carr PF00153.27 CEH14579.1 - 1.3e-46 156.5 1.8 5.8e-18 64.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.18 CEH14580.1 - 1.4e-07 31.5 9.9 2.3e-07 30.8 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 CEH14582.1 - 3.7e-58 197.4 0.0 8.7e-37 126.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 HSP70 PF00012.20 CEH14583.1 - 5.5e-258 857.1 11.3 6.3e-258 856.9 11.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEH14583.1 - 7e-19 67.8 0.7 3.5e-17 62.2 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Spectrin PF00435.21 CEH14583.1 - 0.012 16.1 8.6 0.58 10.7 0.5 3.0 3 0 0 3 3 3 0 Spectrin repeat DUF4624 PF15417.6 CEH14583.1 - 0.023 14.5 0.2 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4624) Hydantoinase_A PF01968.18 CEH14583.1 - 0.025 13.8 4.0 0.031 13.5 0.2 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase ApbA_C PF08546.11 CEH14583.1 - 0.043 14.0 0.1 16 5.7 0.0 2.9 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal FtsA PF14450.6 CEH14583.1 - 0.056 13.9 1.7 21 5.6 0.0 3.4 3 0 0 3 3 3 0 Cell division protein FtsA FGGY_C PF02782.16 CEH14583.1 - 0.057 13.1 0.0 0.47 10.1 0.0 2.5 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain FUSC PF04632.12 CEH14583.1 - 0.062 11.8 0.9 0.1 11.1 0.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF778 PF05608.12 CEH14583.1 - 0.15 12.5 0.8 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF778) FIVAR PF07554.13 CEH14583.1 - 0.63 10.8 8.1 0.82 10.5 3.4 3.1 3 0 0 3 3 3 0 FIVAR domain Ribosomal_L2_C PF03947.18 CEH14584.1 - 2.9e-45 153.5 3.5 5.5e-45 152.6 3.5 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CEH14584.1 - 1.7e-16 60.0 0.0 3.9e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.16 CEH14585.1 - 1.5e-26 93.2 40.3 4.8e-25 88.2 34.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Band_7 PF01145.25 CEH14587.1 - 1.5e-25 90.2 0.7 2.2e-25 89.7 0.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family sCache_3_2 PF17203.4 CEH14587.1 - 0.12 12.5 2.4 0.61 10.2 0.1 2.3 2 0 0 2 2 2 0 Single cache domain 3 DUF2605 PF10792.9 CEH14587.1 - 0.3 11.0 3.4 19 5.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) Vps52 PF04129.12 CEH14588.1 - 1.1e-32 113.4 0.0 4.1e-29 101.7 0.0 2.2 2 0 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 CEH14588.1 - 5.6e-09 35.0 1.5 1.4e-08 33.7 1.5 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec3 Zn_clus PF00172.18 CEH14589.1 - 4.8e-10 39.4 22.9 6.8e-06 26.1 8.1 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PRMT5 PF05185.16 CEH14590.1 - 6.6e-61 205.1 0.0 1.2e-60 204.3 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 CEH14590.1 - 4.2e-55 186.7 0.0 1.6e-54 184.8 0.0 1.8 1 1 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 CEH14590.1 - 4.8e-49 166.6 0.0 7.3e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Oxidored_FMN PF00724.20 CEH14590.1 - 6.1e-35 121.1 0.0 1.8e-32 113.0 0.0 2.3 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Methyltransf_25 PF13649.6 CEH14590.1 - 0.00013 22.6 0.0 0.00029 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH14590.1 - 0.005 16.7 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH14590.1 - 0.011 16.4 0.0 0.03 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 CEH14591.1 - 6e-24 83.9 9.1 0.00099 19.9 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH14591.1 - 4e-17 62.3 6.2 6.2e-08 32.8 0.3 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEH14591.1 - 2.4e-06 27.6 1.5 0.0002 21.3 0.6 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DHC_N1 PF08385.12 CEH14594.1 - 4.1e-119 398.8 0.4 4.1e-119 398.8 0.4 2.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CEH14594.1 - 6.9e-104 348.1 0.2 6.9e-104 348.1 0.2 2.2 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CEH14594.1 - 3.3e-93 312.2 0.0 1.3e-92 310.3 0.0 2.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 CEH14594.1 - 3.9e-43 147.1 0.0 4.6e-36 124.0 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_8 PF12780.7 CEH14594.1 - 1.2e-39 136.3 0.0 4.1e-39 134.5 0.0 2.1 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 CEH14594.1 - 1.3e-31 109.5 0.0 4.3e-13 49.4 0.0 6.0 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CEH14594.1 - 2.8e-15 56.5 0.0 7.7e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CEH14594.1 - 8.3e-15 55.4 0.0 0.002 18.6 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEH14594.1 - 4.4e-13 49.7 3.8 0.0027 18.0 0.0 6.1 6 1 1 7 7 6 3 AAA domain AAA_16 PF13191.6 CEH14594.1 - 2.2e-11 44.5 4.9 0.48 10.8 0.4 6.6 5 1 0 6 6 5 3 AAA ATPase domain AAA_18 PF13238.6 CEH14594.1 - 2.2e-07 31.5 0.0 3 8.4 0.0 4.9 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 CEH14594.1 - 3.7e-07 29.5 0.0 0.0039 16.3 0.0 3.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_30 PF13604.6 CEH14594.1 - 1.7e-05 24.6 0.8 8.3 6.1 0.0 4.9 4 1 0 4 4 4 0 AAA domain AAA_33 PF13671.6 CEH14594.1 - 3.2e-05 24.1 3.0 1.1 9.4 0.0 4.7 4 0 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 CEH14594.1 - 9.1e-05 22.3 0.0 0.048 13.4 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CEH14594.1 - 0.00011 21.7 0.3 0.85 9.0 0.0 3.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CEH14594.1 - 0.00012 22.4 3.8 0.24 11.7 0.0 5.3 5 1 1 6 6 5 1 AAA domain AAA_11 PF13086.6 CEH14594.1 - 0.00018 21.4 0.0 1.1 9.0 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_lid_1 PF17857.1 CEH14594.1 - 0.00019 21.6 0.0 0.00057 20.1 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_29 PF13555.6 CEH14594.1 - 0.00036 20.2 0.1 6.5 6.6 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain Rad17 PF03215.15 CEH14594.1 - 0.00059 19.8 0.1 21 5.0 0.0 5.0 5 0 0 5 5 5 0 Rad17 P-loop domain ABC_tran PF00005.27 CEH14594.1 - 0.00095 19.7 0.6 9.9 6.7 0.0 4.5 4 0 0 4 4 3 0 ABC transporter AAA_25 PF13481.6 CEH14594.1 - 0.0049 16.5 0.2 0.81 9.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CEH14594.1 - 0.019 15.3 0.5 20 5.6 0.0 4.2 4 0 0 4 4 4 0 RNA helicase RuvB_N PF05496.12 CEH14594.1 - 0.037 13.8 0.1 10 5.8 0.0 3.7 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CEH14594.1 - 0.043 13.8 0.0 3.4 7.7 0.0 3.3 3 0 0 3 3 2 0 AAA domain ResIII PF04851.15 CEH14594.1 - 0.067 13.2 0.0 19 5.2 0.0 3.6 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 CEH14594.1 - 0.1 12.3 0.0 18 5.0 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.6 CEH14594.1 - 0.19 11.9 2.3 97 3.2 0.2 4.7 5 0 0 5 5 4 0 AAA domain TsaE PF02367.17 CEH14594.1 - 0.24 11.4 2.1 13 5.8 0.0 4.1 5 0 0 5 5 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cut8 PF08559.10 CEH14595.1 - 1.4e-08 34.7 0.0 3.8e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Cut8, nuclear proteasome tether protein RNase_P_p30 PF01876.16 CEH14596.1 - 8.2e-44 149.6 0.0 2.8e-43 147.9 0.0 1.9 1 1 0 1 1 1 1 RNase P subunit p30 LIM_bind PF01803.16 CEH14597.1 - 2.4e-39 135.3 0.0 1.6e-38 132.6 0.0 2.2 1 1 0 1 1 1 1 LIM-domain binding protein DUF3546 PF12066.8 CEH14598.1 - 7.8e-15 55.0 1.0 2.4e-14 53.5 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 CEH14598.1 - 2.1e-06 28.3 0.0 7.5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Arsenite-resistance protein 2 HTH_Tnp_Tc3_2 PF01498.18 CEH14599.1 - 0.089 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Transposase TFIIF_alpha PF05793.12 CEH14600.1 - 0.067 11.8 12.9 0.089 11.4 12.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BSP_II PF05432.11 CEH14600.1 - 0.1 12.3 8.9 0.16 11.6 8.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2457 PF10446.9 CEH14600.1 - 0.89 8.6 21.6 1.4 8.0 21.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.13 CEH14600.1 - 1.1 9.3 9.9 1.7 8.7 9.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 CEH14600.1 - 6.2 6.0 19.3 8.3 5.6 19.3 1.1 1 0 0 1 1 1 0 BUD22 Nop52 PF05997.12 CEH14601.1 - 1.2e-68 231.2 0.0 1.5e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 CEH14601.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II PALP PF00291.25 CEH14602.1 - 4.3e-66 223.3 0.1 5.7e-66 222.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_C48 PF02902.19 CEH14603.1 - 3.8e-28 98.8 0.0 9.9e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Arf PF00025.21 CEH14604.1 - 8.8e-64 214.1 0.0 1e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CEH14604.1 - 2.8e-12 46.5 0.1 1.7e-07 30.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CEH14604.1 - 7.9e-11 42.2 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEH14604.1 - 4.1e-09 36.2 0.0 5.1e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CEH14604.1 - 1.7e-07 31.3 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEH14604.1 - 2.5e-07 30.3 0.0 3.1e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEH14604.1 - 6.9e-07 28.9 0.0 9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit CdhD PF03599.16 CEH14604.1 - 0.24 10.0 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit ABC_membrane PF00664.23 CEH14605.1 - 8.6e-57 192.9 24.4 3.1e-29 102.5 10.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEH14605.1 - 2.7e-43 147.8 3.6 5.4e-18 65.8 0.0 3.8 2 1 1 3 3 3 3 ABC transporter AAA_21 PF13304.6 CEH14605.1 - 3.1e-13 50.2 2.5 0.00097 19.0 0.1 3.9 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEH14605.1 - 1.2e-10 41.2 5.8 0.0014 18.1 0.3 4.2 2 2 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEH14605.1 - 2e-07 30.7 0.7 0.0032 17.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CEH14605.1 - 2.8e-07 31.1 1.3 0.0086 16.5 0.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 CEH14605.1 - 1.8e-06 28.6 0.4 0.11 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CEH14605.1 - 3.2e-06 27.2 0.2 0.012 15.7 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEH14605.1 - 7.4e-05 22.7 0.7 0.19 11.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CEH14605.1 - 8.1e-05 22.9 1.9 0.071 13.4 0.2 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CEH14605.1 - 0.00021 21.1 1.2 0.67 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CEH14605.1 - 0.00034 20.3 1.1 0.22 11.1 0.1 2.9 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CEH14605.1 - 0.00036 20.6 0.6 0.81 9.7 0.1 2.6 2 0 0 2 2 2 2 Dynamin family T2SSE PF00437.20 CEH14605.1 - 0.00064 18.9 0.2 0.25 10.4 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 CEH14605.1 - 0.001 19.6 0.4 2.6 8.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 CEH14605.1 - 0.0018 17.7 0.5 0.13 11.6 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 CEH14605.1 - 0.0018 17.3 1.3 0.78 8.6 0.2 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 CEH14605.1 - 0.0051 17.2 0.5 2.1 8.8 0.1 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CEH14605.1 - 0.0058 16.8 2.6 12 6.0 0.1 3.7 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 CEH14605.1 - 0.0068 15.9 0.1 3.2 7.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 CEH14605.1 - 0.0071 16.3 1.8 2.8 7.8 0.1 2.8 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 CEH14605.1 - 0.0095 15.9 0.6 0.13 12.2 0.1 2.3 2 0 0 2 2 2 1 NTPase AAA_15 PF13175.6 CEH14605.1 - 0.01 15.6 0.3 4.8 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 CEH14605.1 - 0.013 14.8 0.6 4.1 6.6 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 CEH14605.1 - 0.018 14.6 2.3 2.5 7.7 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 CEH14605.1 - 0.018 15.1 2.5 0.04 14.0 0.3 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 CEH14605.1 - 0.025 14.8 0.2 4.4 7.5 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CEH14605.1 - 0.054 12.7 0.7 2.6 7.2 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 CEH14605.1 - 0.056 13.8 0.2 17 5.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 CEH14605.1 - 0.073 12.8 0.4 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 CEH14605.1 - 0.079 13.2 0.2 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CEH14605.1 - 0.11 12.6 0.7 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CEH14605.1 - 0.35 10.9 3.5 28 4.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CEH14605.1 - 0.43 10.3 3.1 45 3.7 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein MobB PF03205.14 CEH14605.1 - 0.85 9.5 2.5 2.3 8.1 0.1 2.6 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ACT_3 PF10000.9 CEH14606.1 - 2.4e-09 37.0 0.0 4.3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 CEH14606.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 ACT domain adh_short_C2 PF13561.6 CEH14607.1 - 2.8e-41 141.6 0.8 5.5e-40 137.4 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH14607.1 - 1e-39 136.0 0.9 3.4e-38 131.1 0.9 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH14607.1 - 7.9e-10 38.9 0.1 1.4e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CEH14607.1 - 0.0023 17.8 0.0 0.0073 16.2 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Fe-ADH PF00465.19 CEH14608.1 - 6.3e-61 206.2 0.0 1.1e-60 205.4 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CEH14608.1 - 3.6e-11 43.2 0.1 0.00035 20.4 0.0 2.7 2 1 0 2 2 2 2 Iron-containing alcohol dehydrogenase PFK PF00365.20 CEH14608.1 - 0.0066 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase RabGAP-TBC PF00566.18 CEH14609.1 - 5.4e-51 173.3 0.0 1.5e-50 171.8 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EccE PF11203.8 CEH14609.1 - 0.26 11.7 4.7 0.25 11.7 0.9 3.1 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Ras PF00071.22 CEH14610.1 - 7e-58 194.8 0.1 8.2e-58 194.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH14610.1 - 2.9e-20 72.7 0.0 4e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH14610.1 - 1.1e-08 34.8 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEH14610.1 - 3.5e-05 23.4 0.0 6.6e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEH14610.1 - 0.00022 21.2 0.0 0.31 10.9 0.0 2.4 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 CEH14610.1 - 0.004 17.2 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CEH14610.1 - 0.0087 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 CEH14610.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Abhydrolase_2 PF02230.16 CEH14611.1 - 2e-06 27.8 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CEH14611.1 - 0.012 15.3 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 CEH14611.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.22 CEH14611.1 - 0.013 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF2235 PF09994.9 CEH14611.1 - 0.037 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DnaB PF00772.21 CEH14611.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Aminotran_5 PF00266.19 CEH14612.1 - 3.1e-14 52.7 0.0 6.5e-14 51.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V SNARE_assoc PF09335.11 CEH14615.1 - 1.1e-07 32.4 5.5 1.8e-07 31.7 2.0 2.6 2 0 0 2 2 2 1 SNARE associated Golgi protein Sgf11 PF08209.11 CEH14616.1 - 5.7e-10 38.6 0.5 5.7e-10 38.6 0.5 1.6 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 CEH14616.1 - 0.00077 19.3 0.5 0.0034 17.2 0.1 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Yippee-Mis18 PF03226.14 CEH14618.1 - 1.3e-13 51.1 0.3 1.4e-13 50.9 0.3 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Endonuclease_7 PF02945.15 CEH14618.1 - 0.0091 15.9 1.3 0.022 14.6 1.3 1.7 1 1 0 1 1 1 1 Recombination endonuclease VII SelR PF01641.18 CEH14618.1 - 0.027 14.5 0.2 0.034 14.2 0.2 1.1 1 0 0 1 1 1 0 SelR domain Phyto_Pns9_10 PF05878.11 CEH14618.1 - 0.07 12.3 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DZR PF12773.7 CEH14618.1 - 0.09 12.8 0.5 2 8.5 0.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon GYF PF02213.16 CEH14619.1 - 5.8e-17 61.1 1.1 1e-16 60.3 1.1 1.4 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CEH14619.1 - 0.0087 15.9 0.4 0.041 13.7 0.1 2.2 2 0 0 2 2 2 1 GYF domain 2 DUF3292 PF11696.8 CEH14620.1 - 3.1e-184 614.0 2.5 7.9e-145 483.8 0.0 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3292) Hexapep PF00132.24 CEH14621.1 - 3.2e-11 42.5 2.8 5.5e-11 41.8 2.8 1.4 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CEH14621.1 - 1.6e-09 37.3 1.6 2.8e-09 36.6 1.6 1.4 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 CEH14621.1 - 5.3e-07 29.8 0.1 8.6e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase HEAT_2 PF13646.6 CEH14622.1 - 6.8e-28 96.9 8.7 1.6e-16 60.5 0.6 3.6 3 1 1 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 CEH14622.1 - 2.7e-17 61.6 7.2 8.5e-06 26.0 0.0 6.7 6 1 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.22 CEH14622.1 - 2.9e-08 33.3 3.7 0.054 13.8 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.23 CEH14622.1 - 0.00024 21.0 0.3 1.3 9.2 0.1 3.7 2 1 1 3 3 3 2 Armadillo/beta-catenin-like repeat Vitellogenin_N PF01347.22 CEH14622.1 - 0.0017 16.9 0.2 0.37 9.1 0.2 3.2 1 1 2 3 3 3 2 Lipoprotein amino terminal region HEAT_EZ PF13513.6 CEH14622.1 - 0.0019 18.7 10.9 1.7 9.2 0.1 5.7 5 2 2 7 7 7 2 HEAT-like repeat DUF2150 PF09920.9 CEH14622.1 - 0.023 14.7 0.3 7.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) zf-CCCH_6 PF18585.1 CEH14622.1 - 0.087 12.7 0.1 6 6.8 0.1 2.8 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 RNA_pol_Rpc4 PF05132.14 CEH14623.1 - 2e-28 99.7 0.1 2e-28 99.7 0.1 4.7 3 2 1 4 4 4 2 RNA polymerase III RPC4 PI3K_1B_p101 PF10486.9 CEH14624.1 - 3 5.5 9.9 4 5.1 9.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MMR_HSR1_Xtn PF16897.5 CEH14626.1 - 4.3e-39 132.8 0.3 8.1e-39 131.9 0.3 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CEH14626.1 - 9.9e-21 73.6 0.0 4.2e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.23 CEH14626.1 - 1.3e-20 73.6 0.0 3.2e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH14626.1 - 9.9e-12 44.7 0.0 1.9e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CEH14626.1 - 0.00048 20.2 0.2 0.084 12.9 0.0 2.4 1 1 1 2 2 2 1 Dynamin family AAA_18 PF13238.6 CEH14626.1 - 0.0044 17.6 0.0 0.5 10.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 CEH14626.1 - 0.023 13.8 0.1 0.056 12.5 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain ABC_tran PF00005.27 CEH14626.1 - 0.057 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 CEH14626.1 - 0.17 12.1 0.4 0.34 11.2 0.4 1.5 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.18 CEH14627.1 - 1.4e-86 290.8 0.4 2.1e-86 290.2 0.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEH14627.1 - 0.0001 21.5 14.2 0.0001 21.5 14.2 1.8 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family CS PF04969.16 CEH14628.1 - 5.6e-05 24.1 0.1 9.7e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 CS domain tRNA-synt_1g PF09334.11 CEH14628.1 - 0.0068 15.2 0.3 0.0088 14.8 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) Med15 PF09606.10 CEH14628.1 - 0.046 12.4 5.2 0.061 12.0 5.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CRAL_TRIO PF00650.20 CEH14629.1 - 1.6e-34 118.9 0.0 2.7e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEH14629.1 - 7.4e-13 48.5 0.6 1.6e-12 47.4 0.6 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ThiS PF02597.20 CEH14629.1 - 0.00045 20.8 0.0 0.0045 17.6 0.0 2.6 1 1 0 1 1 1 1 ThiS family DUF5486 PF17588.2 CEH14629.1 - 6.8 6.7 7.9 0.67 9.9 0.5 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5486) 5_nucleotid_C PF02872.18 CEH14630.1 - 0.013 15.8 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Defensin_beta PF00711.19 CEH14631.1 - 0.094 12.8 2.7 3.8 7.6 0.4 3.3 2 0 0 2 2 2 0 Beta defensin Defensin_1 PF00323.19 CEH14631.1 - 0.47 11.1 5.9 5.6 7.6 0.8 3.0 2 0 0 2 2 2 0 Mammalian defensin Cytidylate_kin PF02224.18 CEH14632.1 - 0.44 10.2 5.6 0.54 9.9 5.6 1.1 1 0 0 1 1 1 0 Cytidylate kinase RT_RNaseH PF17917.1 CEH14634.1 - 2.9e-32 111.1 0.1 6e-32 110.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEH14634.1 - 6.9e-32 109.5 0.0 1.5e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEH14634.1 - 4.2e-26 91.8 0.0 7.3e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEH14634.1 - 6.2e-17 61.9 0.0 1.4e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEH14634.1 - 8.6e-12 45.0 0.4 2.3e-11 43.6 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEH14634.1 - 0.005 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Gti1_Pac2 PF09729.9 CEH14635.1 - 1.4e-31 110.0 3.5 7.5e-26 91.3 0.0 2.8 2 1 1 3 3 3 2 Gti1/Pac2 family DUF3712 PF12505.8 CEH14637.1 - 8.8e-17 61.5 0.0 8e-09 35.8 0.0 5.3 5 1 0 5 5 5 3 Protein of unknown function (DUF3712) LEA_2 PF03168.13 CEH14637.1 - 1.5e-05 25.5 0.1 0.11 13.1 0.0 4.6 4 0 0 4 4 4 2 Late embryogenesis abundant protein DUF4982 PF16355.5 CEH14637.1 - 0.023 14.6 0.0 0.072 13.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) 60KD_IMP PF02096.20 CEH14638.1 - 0.00013 21.9 0.0 0.00014 21.8 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Sensor PF13796.6 CEH14638.1 - 0.03 14.4 0.6 0.042 13.9 0.6 1.3 1 1 0 1 1 1 0 Putative sensor NEMP PF10225.9 CEH14638.1 - 0.033 13.9 0.0 0.036 13.7 0.0 1.0 1 0 0 1 1 1 0 NEMP family Gram_pos_anchor PF00746.21 CEH14640.1 - 0.085 12.8 1.8 0.085 12.8 1.8 1.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif AF-4 PF05110.13 CEH14641.1 - 1.2 7.2 13.2 2.4 6.2 13.2 1.5 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4551 PF15087.6 CEH14641.1 - 2.3 6.9 7.2 3.8 6.2 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Gln-synt_C PF00120.24 CEH14643.1 - 6.3e-18 64.9 0.0 7.2e-15 54.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CEH14643.1 - 3e-12 46.1 0.0 5e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain FAD_binding_2 PF00890.24 CEH14643.1 - 0.0032 16.6 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2985 PF11204.8 CEH14644.1 - 7.9e-28 96.4 3.5 1.2e-27 95.8 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) WES_acyltransf PF03007.16 CEH14645.1 - 7e-16 58.8 0.0 1.8e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 CEH14645.1 - 1.5e-09 38.0 0.0 3.5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) SLAC1 PF03595.17 CEH14646.1 - 2.2e-68 230.9 46.6 2.5e-68 230.7 46.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ABC1 PF03109.16 CEH14647.1 - 8.1e-25 87.3 0.0 1.5e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CEH14647.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family KH_5 PF13184.6 CEH14647.1 - 0.19 11.9 0.1 0.74 9.9 0.0 2.0 2 0 0 2 2 2 0 NusA-like KH domain DUF4611 PF15387.6 CEH14649.1 - 1.4 9.2 6.5 0.11 12.7 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MIS13 PF08202.11 CEH14650.1 - 3.9e-15 55.9 6.0 2.5e-14 53.3 3.9 3.1 2 1 0 2 2 2 1 Mis12-Mtw1 protein family WD40 PF00400.32 CEH14651.1 - 4.7e-07 30.4 9.0 0.52 11.3 0.0 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat SRA1 PF07304.11 CEH14651.1 - 1.1e-05 25.2 0.2 7.7e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 CEH14651.1 - 0.012 15.2 0.2 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 MFAP1 PF06991.11 CEH14653.1 - 4.8e-47 160.6 31.8 4.8e-47 160.6 31.8 3.6 3 1 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing tRNA-synt_1 PF00133.22 CEH14654.1 - 3.6e-38 131.2 0.0 8.9e-30 103.5 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CEH14654.1 - 9.3e-16 57.5 0.0 3.2e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CEH14654.1 - 4.6e-11 42.9 0.1 1e-10 41.8 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CEH14654.1 - 3.2e-07 30.0 0.0 7.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Cys_Met_Meta_PP PF01053.20 CEH14655.1 - 1.1e-121 406.0 0.0 1.8e-121 405.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 CEH14655.1 - 2.7e-12 46.7 3.4 2.7e-12 46.7 3.4 3.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CEH14655.1 - 4.7e-07 30.1 0.0 1.6e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 CEH14655.1 - 0.008 15.7 0.6 0.017 14.6 0.6 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature RPA_interact_C PF14768.6 CEH14658.1 - 0.081 13.5 0.2 0.19 12.3 0.1 1.6 2 0 0 2 2 2 0 Replication protein A interacting C-terminal Pyr_redox_2 PF07992.14 CEH14659.1 - 2.1e-69 234.0 0.5 1.3e-43 149.3 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEH14659.1 - 3.9e-32 110.8 1.0 3.9e-32 110.8 1.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CEH14659.1 - 2.8e-22 79.1 10.4 1.4e-18 67.2 0.1 3.8 3 1 1 4 4 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEH14659.1 - 1.7e-13 50.5 1.9 1.1e-07 31.4 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEH14659.1 - 4.8e-06 26.2 0.4 1.7e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CEH14659.1 - 6.7e-06 25.1 4.6 0.11 11.2 1.3 3.5 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 CEH14659.1 - 0.001 19.3 1.5 0.0028 17.8 1.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CEH14659.1 - 0.0014 17.9 0.3 0.0036 16.5 0.0 1.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 CEH14659.1 - 0.0021 18.5 0.3 0.2 12.1 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 CEH14659.1 - 0.0083 15.3 7.3 0.1 11.7 3.4 3.0 3 0 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 CEH14659.1 - 0.034 14.0 0.0 0.034 14.0 0.0 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CEH14659.1 - 1.2 8.1 5.6 2.9 6.9 3.7 2.4 2 1 0 2 2 2 0 Glucose inhibited division protein A SMK-1 PF04802.15 CEH14661.1 - 7.8e-71 237.9 0.1 1.8e-70 236.7 0.0 1.7 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Pribosyltran PF00156.27 CEH14663.1 - 3.2e-12 46.3 0.4 4.6e-12 45.7 0.4 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF3718 PF12514.8 CEH14663.1 - 0.00054 20.1 0.5 2.1 8.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3718) Fels1 PF05666.11 CEH14663.1 - 0.019 14.6 0.3 7.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Fels-1 Prophage Protein-like NDK PF00334.19 CEH14664.1 - 5.8e-32 110.5 0.0 8.5e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glycos_transf_4 PF00953.21 CEH14665.1 - 3e-32 111.8 5.0 7.8e-32 110.5 5.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 4 Mito_carr PF00153.27 CEH14667.1 - 1.9e-67 223.2 5.1 7.6e-24 83.5 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein ABC_membrane_2 PF06472.15 CEH14668.1 - 4.7e-93 311.5 0.7 6.1e-93 311.1 0.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CEH14668.1 - 4.5e-18 66.1 0.0 8.4e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CEH14668.1 - 0.0096 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CEH14668.1 - 0.012 16.1 0.0 0.012 16.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 CEH14668.1 - 0.023 14.1 0.1 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF2990 PF11693.8 CEH14668.1 - 0.038 14.2 0.1 0.52 10.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) AAA_29 PF13555.6 CEH14668.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HA2 PF04408.23 CEH14669.1 - 4.1e-15 56.0 2.6 1e-14 54.7 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CEH14669.1 - 1e-14 54.8 0.1 8.5e-14 51.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEH14669.1 - 2.8e-07 30.5 0.4 5.2e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 CEH14669.1 - 6.2e-06 26.8 8.1 0.0064 17.2 0.0 3.3 3 0 0 3 3 3 2 Double-stranded RNA binding motif AAA_19 PF13245.6 CEH14669.1 - 0.00024 21.4 0.0 0.00083 19.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 CEH14669.1 - 0.00035 20.9 0.0 0.00075 19.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA PF00004.29 CEH14670.1 - 3.9e-50 169.7 0.0 3.9e-41 140.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEH14670.1 - 3.4e-09 36.3 0.0 1e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CEH14670.1 - 9.4e-05 22.6 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CEH14670.1 - 0.00015 22.2 0.0 0.00015 22.2 0.0 5.1 5 1 0 5 5 4 1 AAA ATPase domain IstB_IS21 PF01695.17 CEH14670.1 - 0.00016 21.4 0.0 0.00062 19.5 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.6 CEH14670.1 - 0.00031 20.6 0.3 0.37 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CEH14670.1 - 0.0018 18.3 0.0 0.012 15.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CEH14670.1 - 0.0032 18.0 0.0 0.035 14.6 0.0 2.8 2 1 1 3 3 2 1 AAA domain AAA_22 PF13401.6 CEH14670.1 - 0.004 17.4 1.1 0.21 11.9 0.2 3.8 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CEH14670.1 - 0.0062 16.1 0.1 0.082 12.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 CEH14670.1 - 0.027 14.6 0.0 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 CEH14670.1 - 0.044 13.2 0.3 1.1 8.6 0.0 2.6 3 0 0 3 3 3 0 PhoH-like protein AAA_33 PF13671.6 CEH14670.1 - 0.071 13.3 0.0 0.071 13.3 0.0 3.3 4 0 0 4 4 3 0 AAA domain Sigma54_activat PF00158.26 CEH14670.1 - 0.08 12.6 0.0 0.76 9.5 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 CEH14670.1 - 0.088 12.2 1.1 0.29 10.5 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Bromodomain PF00439.25 CEH14670.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Bromodomain RNA_helicase PF00910.22 CEH14670.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 CEH14670.1 - 0.17 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TIP49 PF06068.13 CEH14670.1 - 0.2 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Velvet PF11754.8 CEH14671.1 - 3.7e-67 226.9 0.3 1.4e-66 225.0 0.0 1.9 2 0 0 2 2 2 1 Velvet factor Hydrolase_like PF13242.6 CEH14672.1 - 6.8e-20 70.9 0.1 1.9e-19 69.5 0.1 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 CEH14672.1 - 1.5e-16 60.3 0.0 4e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEH14672.1 - 2.4e-05 24.7 0.1 0.025 14.9 0.0 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEH14672.1 - 0.014 15.5 0.0 0.05 13.7 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mito_carr PF00153.27 CEH14673.1 - 4.6e-32 109.8 4.8 3.5e-15 55.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEH14673.1 - 0.0066 15.6 0.2 0.067 12.3 0.1 2.1 2 0 0 2 2 2 1 Gammaproteobacterial serine protease LEA_4 PF02987.16 CEH14673.1 - 0.025 14.6 0.4 0.049 13.7 0.4 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein MFS_1 PF07690.16 CEH14674.1 - 2.9e-40 138.3 54.6 5.6e-32 111.0 18.9 3.9 2 2 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 CEH14674.1 - 2.5e-15 55.9 20.3 3.7e-15 55.4 20.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CEH14674.1 - 1.1e-10 41.0 5.5 1.1e-10 41.0 5.5 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MerC PF03203.14 CEH14674.1 - 6.3 7.3 0.0 6.3 7.3 0.0 4.6 3 1 1 4 4 4 0 MerC mercury resistance protein PALP PF00291.25 CEH14676.1 - 2.9e-31 109.0 0.0 5.9e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 CEH14676.1 - 0.044 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain LAL_C2 PF18603.1 CEH14676.1 - 0.19 11.9 0.0 0.48 10.6 0.0 1.6 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 Packaging_FI PF14000.6 CEH14676.1 - 0.39 11.2 2.8 0.9 10.0 2.8 1.5 1 0 0 1 1 1 0 DNA packaging protein FI FDF PF09532.10 CEH14677.1 - 1.3e-07 32.4 0.6 1.3e-07 32.4 0.6 2.2 1 1 1 2 2 2 1 FDF domain Med3 PF11593.8 CEH14677.1 - 0.53 9.4 12.6 0.88 8.7 12.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LsmAD PF06741.13 CEH14677.1 - 1.6 9.3 3.8 1 9.9 0.1 2.4 2 0 0 2 2 2 0 LsmAD domain Hamartin PF04388.12 CEH14677.1 - 3.3 6.3 7.2 4.4 5.8 7.2 1.3 1 0 0 1 1 1 0 Hamartin protein Ribophorin_I PF04597.14 CEH14678.1 - 2.2e-109 366.6 0.0 2.5e-109 366.4 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I TAP35_44 PF07265.11 CEH14678.1 - 0.73 9.9 3.5 0.28 11.2 0.2 1.9 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 DAPG_hydrolase PF18089.1 CEH14679.1 - 5.2e-73 245.3 0.0 6.3e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 DAPG hydrolase PhiG domain Yos1 PF08571.10 CEH14680.1 - 1.7e-30 105.1 0.4 2e-30 104.9 0.4 1.1 1 0 0 1 1 1 1 Yos1-like Phosducin PF02114.16 CEH14681.1 - 9.7e-10 37.8 0.5 3.1e-09 36.2 0.0 2.0 2 1 1 3 3 3 1 Phosducin DUF4611 PF15387.6 CEH14681.1 - 0.015 15.5 7.0 0.38 11.0 2.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NAM-associated PF14303.6 CEH14681.1 - 4.3 8.0 9.4 0.73 10.5 0.8 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain tRNA-synt_1c PF00749.21 CEH14682.1 - 8.9e-106 353.3 0.0 1.2e-105 352.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CEH14682.1 - 2.5e-29 102.4 0.0 4e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 CEH14682.1 - 0.02 14.2 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_3 PF14497.6 CEH14682.1 - 0.1 12.8 0.0 1.3 9.3 0.0 2.6 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain DUF3567 PF12091.8 CEH14682.1 - 0.17 12.0 0.2 26 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) AMP-binding PF00501.28 CEH14683.1 - 1.9e-63 214.5 0.0 3.8e-63 213.6 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEH14683.1 - 0.00018 22.4 0.0 0.47 11.5 0.0 3.2 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain CSN7a_helixI PF18392.1 CEH14684.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Get5_C PF18514.1 CEH14685.1 - 0.05 13.3 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Get5 C-terminal domain Antimicrobial15 PF08110.12 CEH14685.1 - 0.11 12.7 0.2 0.27 11.5 0.2 1.6 1 0 0 1 1 1 0 Ocellatin family Fungal_trans PF04082.18 CEH14686.1 - 4.5e-08 32.5 0.1 7.3e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH14686.1 - 2.3e-06 27.6 10.4 5.1e-06 26.5 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 CEH14686.1 - 0.085 13.4 5.1 0.24 11.9 5.1 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Selenoprotein_S PF06936.11 CEH14686.1 - 0.19 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) EB1 PF03271.17 CEH14688.1 - 4.1e-16 58.9 0.6 7.3e-16 58.1 0.6 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CEH14688.1 - 4.9e-05 23.5 0.2 7.8e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 CEH14688.1 - 0.037 14.1 0.2 0.058 13.5 0.2 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein DUF1269 PF06897.12 CEH14688.1 - 0.084 13.2 0.1 0.084 13.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) HSBP1 PF06825.12 CEH14688.1 - 0.096 12.6 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Kdo PF06293.14 CEH14689.1 - 0.0018 17.6 0.1 0.0047 16.3 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEH14689.1 - 0.0054 15.5 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CEH14689.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain YabA PF06156.13 CEH14690.1 - 0.17 12.6 0.8 0.2 12.3 0.8 1.3 1 1 0 1 1 1 0 Initiation control protein YabA Grg1 PF11034.8 CEH14691.1 - 6.4e-29 100.0 9.9 7.2e-29 99.8 9.9 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 LEA_1 PF03760.15 CEH14691.1 - 0.71 10.5 8.8 2 9.1 8.8 2.0 1 1 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Peptidase_M24 PF00557.24 CEH14692.1 - 4.6e-24 85.3 0.2 6e-24 84.9 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 MRP-S25 PF13741.6 CEH14693.1 - 1.1e-34 120.0 0.0 2e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 Maf PF02545.14 CEH14694.1 - 4.5e-45 153.5 0.0 5.2e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Ndufs5 PF10200.9 CEH14695.1 - 4.1e-05 23.7 0.5 6.2e-05 23.2 0.5 1.4 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 CEH14695.1 - 0.017 15.5 3.5 0.017 15.5 3.5 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3128) COX6B PF02297.17 CEH14695.1 - 0.2 11.9 0.4 0.2 11.9 0.4 2.5 2 1 1 3 3 3 0 Cytochrome oxidase c subunit VIb zf-HC5HC2H_2 PF13832.6 CEH14696.1 - 1.2e-32 112.3 9.4 1.2e-32 112.3 9.4 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CEH14696.1 - 2.3e-24 85.5 7.3 2.3e-24 85.5 7.3 3.4 3 1 0 3 3 3 2 PHD-like zinc-binding domain EPL1 PF10513.9 CEH14696.1 - 1.3e-21 77.6 0.2 1.3e-21 77.6 0.2 4.4 3 1 1 4 4 4 1 Enhancer of polycomb-like Bromodomain PF00439.25 CEH14696.1 - 4.4e-18 65.1 0.0 8.3e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 CEH14696.1 - 1.2e-14 53.6 2.6 1.2e-14 53.6 2.6 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CEH14696.1 - 1e-09 38.1 9.2 1e-09 38.1 9.2 2.7 2 0 0 2 2 2 2 PHD-finger PWWP PF00855.17 CEH14696.1 - 0.00023 21.5 0.1 0.00023 21.5 0.1 2.6 2 0 0 2 2 2 1 PWWP domain Glyco_transf_8 PF01501.20 CEH14697.1 - 5.2e-10 39.3 0.0 1.9e-08 34.2 0.0 2.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mucin PF01456.17 CEH14701.1 - 0.0047 16.9 14.4 0.0059 16.6 14.4 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein CytochromB561_N PF09786.9 CEH14701.1 - 0.055 12.5 2.8 0.062 12.3 2.8 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF2448 PF10476.9 CEH14701.1 - 0.14 12.0 1.2 0.22 11.3 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Joubert PF15392.6 CEH14701.1 - 0.22 11.2 0.8 0.26 11.0 0.8 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated DUF1180 PF06679.12 CEH14701.1 - 1.3 9.4 10.5 2.6 8.4 10.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) SOG2 PF10428.9 CEH14701.1 - 1.6 7.9 7.9 1.7 7.8 7.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein WD40 PF00400.32 CEH14702.1 - 5.6e-54 178.9 30.9 4.7e-09 36.7 0.0 9.4 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH14702.1 - 6.2e-17 61.7 2.5 0.0037 17.5 0.0 5.5 3 3 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEH14702.1 - 2.4e-08 33.1 5.0 0.015 14.0 0.1 4.4 3 1 1 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.11 CEH14702.1 - 0.00026 20.9 0.0 0.0028 17.6 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEH14702.1 - 0.022 13.7 0.1 5.4 5.9 0.0 3.8 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CEH14702.1 - 0.024 13.6 0.3 1.8 7.4 0.1 2.6 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain NLE PF08154.12 CEH14702.1 - 0.024 15.1 0.0 0.045 14.3 0.0 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain Nbas_N PF15492.6 CEH14702.1 - 0.042 13.2 0.5 8.6 5.6 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal ABC2_membrane PF01061.24 CEH14703.1 - 6.9e-39 133.4 18.9 8.8e-39 133.1 18.9 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CEH14703.1 - 1.4e-25 90.4 0.2 3e-25 89.3 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CEH14703.1 - 2.4e-05 24.3 0.6 0.081 12.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CEH14703.1 - 0.00091 19.8 0.0 0.0044 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CEH14703.1 - 0.00092 19.1 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CEH14703.1 - 0.00096 19.6 0.7 0.002 18.5 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEH14703.1 - 0.0016 18.7 0.1 0.074 13.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEH14703.1 - 0.0023 17.5 0.1 0.0079 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CEH14703.1 - 0.0073 16.4 0.1 0.022 14.8 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 CEH14703.1 - 0.0076 16.5 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CEH14703.1 - 0.015 15.1 0.2 0.032 14.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 CEH14703.1 - 0.026 14.6 0.3 0.054 13.6 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain T2SSE PF00437.20 CEH14703.1 - 0.06 12.4 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 CEH14703.1 - 0.084 13.4 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEH14703.1 - 0.1 12.5 0.5 0.2 11.5 0.0 1.7 2 0 0 2 2 1 0 NACHT domain FeoB_N PF02421.18 CEH14703.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B MeaB PF03308.16 CEH14703.1 - 0.15 11.0 2.0 0.23 10.4 0.2 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 CEH14703.1 - 0.16 12.3 0.0 0.41 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 CEH14703.1 - 1.5 7.9 25.8 8.8 5.3 25.8 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein Zn_clus PF00172.18 CEH14704.1 - 5.1e-07 29.7 8.9 1e-06 28.7 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4061 PF13270.6 CEH14704.1 - 0.065 13.6 0.4 0.15 12.4 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) DUF3294 PF07957.11 CEH14704.1 - 0.11 12.2 0.6 0.19 11.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) TPR_MLP1_2 PF07926.12 CEH14704.1 - 3 7.9 10.1 0.84 9.7 6.0 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lipase_3 PF01764.25 CEH14705.1 - 1.3e-15 57.5 0.0 9.5e-11 41.7 0.0 2.5 2 0 0 2 2 2 2 Lipase (class 3) ThiD2 PF17792.1 CEH14706.1 - 0.038 14.5 0.1 0.44 11.0 0.0 2.2 2 0 0 2 2 2 0 ThiD2 family tRNA-synt_2 PF00152.20 CEH14707.1 - 7e-77 258.6 0.0 9e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEH14707.1 - 1.4e-06 28.2 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CEH14707.1 - 0.09 12.2 0.2 12 5.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) RVT_1 PF00078.27 CEH14709.1 - 3.3e-24 85.6 0.0 5.1e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CEH14709.1 - 2.8e-13 49.8 0.0 5.8e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEH14709.1 - 2.6e-05 24.5 0.0 4.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEH14711.1 - 1.3e-09 38.2 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEH14711.1 - 0.00069 19.7 0.3 0.0015 18.6 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CEH14712.1 - 2.2e-31 108.2 0.0 4.4e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEH14712.1 - 4.1e-28 97.4 0.2 2e-13 50.2 0.0 2.4 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEH14712.1 - 5.2e-10 39.2 0.2 2.2e-08 33.9 0.1 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEH14713.1 - 3.3e-05 23.5 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 CEH14714.1 - 0.0019 18.5 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein tRNA-synt_His PF13393.6 CEH14716.1 - 1.6e-37 129.5 1.7 3.8e-33 115.1 0.0 3.0 3 0 0 3 3 3 2 Histidyl-tRNA synthetase ERCC4 PF02732.15 CEH14716.1 - 7.8e-22 78.1 0.0 1.7e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain WHEP-TRS PF00458.20 CEH14716.1 - 5.4e-09 36.1 5.5 6.3e-09 35.9 3.3 2.3 2 0 0 2 2 2 1 WHEP-TRS domain HGTP_anticodon PF03129.20 CEH14716.1 - 3.3e-07 30.4 0.0 1.2e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CEH14716.1 - 0.0027 17.3 0.0 0.0059 16.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 CEH14716.1 - 0.016 14.3 0.5 0.15 11.1 0.2 2.4 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) PRIMA1 PF16101.5 CEH14716.1 - 4.5 7.3 5.1 9.9 6.2 5.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mei5 PF10376.9 CEH14717.1 - 0.017 15.0 0.3 0.036 13.9 0.3 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein Complex1_30kDa PF00329.19 CEH14718.1 - 3.8e-47 159.9 0.0 5.5e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit HutD PF05962.11 CEH14719.1 - 0.0066 16.4 0.7 0.0084 16.1 0.7 1.1 1 0 0 1 1 1 1 HutD DUF1501 PF07394.12 CEH14719.1 - 0.039 13.0 4.2 0.048 12.7 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4200 PF13863.6 CEH14719.1 - 0.085 13.3 13.9 0.11 12.9 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF737 PF05300.11 CEH14719.1 - 0.37 11.1 11.6 0.42 11.0 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Herpes_UL6 PF01763.16 CEH14719.1 - 0.48 8.9 2.9 0.58 8.6 2.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF2185 PF09951.9 CEH14720.1 - 2.8e-21 75.1 0.0 3.7e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2185) Barwin PF00967.17 CEH14720.1 - 0.087 12.7 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Barwin family ketoacyl-synt PF00109.26 CEH14722.1 - 1.9e-57 194.8 0.6 4.7e-57 193.5 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 CEH14722.1 - 2.1e-24 85.9 0.0 3.4e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Ketoacyl-synt_C PF02801.22 CEH14722.1 - 9.9e-16 57.8 2.0 3.2e-14 52.9 0.9 3.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 CEH14722.1 - 4.1e-06 27.2 0.2 1.9e-05 25.1 0.2 2.2 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 CEH14722.1 - 1.3e-05 25.5 0.0 3.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 CEH14722.1 - 0.024 14.0 1.5 0.046 13.1 0.3 2.1 2 0 0 2 2 2 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 CEH14722.1 - 0.21 11.4 5.2 0.64 9.9 0.7 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.26 CEH14723.1 - 5e-21 75.0 0.2 1.2e-20 73.8 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.7 CEH14723.1 - 1.1e-18 68.6 0.3 1.8e-17 64.7 0.0 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family ADH_N_2 PF16884.5 CEH14723.1 - 4.2e-18 65.2 0.0 8.7e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 CEH14723.1 - 2.2e-07 32.0 0.0 9e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Chlorophyllase2 PF12740.7 CEH14723.1 - 8.3e-05 21.6 0.1 0.00022 20.2 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 CEH14723.1 - 0.00028 20.6 0.0 0.0014 18.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH14723.1 - 0.0037 16.6 0.0 0.009 15.3 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CEH14723.1 - 0.052 13.6 0.0 0.18 11.9 0.0 2.0 1 1 0 1 1 1 0 Thioesterase domain LIDHydrolase PF10230.9 CEH14723.1 - 0.061 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF2855 PF11017.8 CEH14723.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2855) DASH_Duo1 PF08651.10 CEH14723.1 - 0.16 11.8 0.2 0.43 10.4 0.1 1.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 Abhydrolase_3 PF07859.13 CEH14724.1 - 8.7e-19 68.2 0.7 4.7e-18 65.8 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEH14724.1 - 2.8e-10 39.6 0.0 4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 CEH14724.1 - 0.001 19.7 2.4 0.0026 18.4 1.7 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Lipase PF00151.19 CEH14724.1 - 0.011 15.1 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 Lipase Peptidase_S9 PF00326.21 CEH14724.1 - 0.054 13.0 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.28 CEH14724.1 - 0.13 11.1 0.0 11 4.7 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family BAAT_C PF08840.11 CEH14724.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal SGL PF08450.12 CEH14725.1 - 0.016 14.8 0.0 3.8 7.0 0.0 2.8 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Ldl_recept_b PF00058.17 CEH14725.1 - 0.017 15.6 0.4 2.7 8.5 0.0 3.2 3 0 0 3 3 3 0 Low-density lipoprotein receptor repeat class B Nop14 PF04147.12 CEH14725.1 - 0.019 13.2 2.1 0.025 12.8 2.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CEH14725.1 - 0.034 12.5 2.7 0.049 11.9 2.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Glypican PF01153.19 CEH14725.1 - 0.14 11.0 1.8 0.2 10.4 1.8 1.1 1 0 0 1 1 1 0 Glypican Sporozoite_P67 PF05642.11 CEH14725.1 - 0.16 10.1 0.7 0.24 9.4 0.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Presenilin PF01080.17 CEH14725.1 - 0.22 10.2 1.7 0.31 9.8 1.7 1.1 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 CEH14725.1 - 0.24 11.1 0.4 0.49 10.1 0.4 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MDM31_MDM32 PF08118.11 CEH14725.1 - 0.37 9.4 0.3 0.52 8.9 0.3 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF3915 PF13054.6 CEH14725.1 - 0.54 10.2 1.5 1.1 9.3 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) XAP5 PF04921.14 CEH14725.1 - 0.72 9.6 3.5 1.1 9.0 3.5 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Roughex PF06020.11 CEH14725.1 - 1.1 8.3 9.5 1.8 7.6 9.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Rep_4 PF05797.11 CEH14725.1 - 1.4 8.0 5.5 2 7.4 5.5 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) TRAP_alpha PF03896.16 CEH14725.1 - 2.4 7.3 4.1 3.6 6.7 4.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ketoacyl-synt PF00109.26 CEH14726.1 - 2.2e-52 178.1 0.2 6.9e-52 176.5 0.2 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CEH14726.1 - 3.2e-39 134.7 0.4 3e-38 131.5 0.0 2.4 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 CEH14726.1 - 4.6e-28 97.6 0.6 1.1e-27 96.3 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 CEH14726.1 - 5.5e-19 68.5 0.1 1.3e-18 67.3 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 CEH14726.1 - 3.1e-10 40.0 0.0 6.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.23 CEH14726.1 - 1.6e-05 24.4 0.3 4e-05 23.1 0.3 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 CEH14726.1 - 2.7e-05 23.7 0.0 7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 CEH14726.1 - 0.00052 20.3 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 CEH14726.1 - 0.0088 16.5 0.0 0.025 15.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 CEH14726.1 - 0.086 12.7 0.1 0.43 10.5 0.1 2.3 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Lipase_GDSL_2 PF13472.6 CEH14727.1 - 0.005 17.2 0.1 0.96 9.8 0.0 2.5 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CEH14727.1 - 0.012 15.7 0.5 0.7 9.8 0.5 2.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Mcp5_PH PF12814.7 CEH14728.1 - 3.8e-41 140.0 0.0 7.6e-41 139.1 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 CEH14728.1 - 0.00027 21.4 0.0 0.00065 20.2 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF2937 PF11157.8 CEH14728.1 - 0.077 12.7 2.2 0.28 10.9 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF1664 PF07889.12 CEH14728.1 - 2.7 8.0 11.3 3 7.9 0.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) IMS PF00817.20 CEH14729.1 - 3.2e-35 121.4 0.0 8.6e-35 119.9 0.0 1.7 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CEH14729.1 - 0.00096 19.8 0.0 0.003 18.2 0.0 1.9 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CEH14729.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif Hva1_TUDOR PF11160.8 CEH14730.1 - 2.9e-16 59.3 4.3 3.4e-16 59.1 4.3 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Sec23_trunk PF04811.15 CEH14731.1 - 1.1e-72 244.6 0.0 1.7e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CEH14731.1 - 5.9e-23 80.6 0.6 1.3e-22 79.6 0.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CEH14731.1 - 2.5e-15 56.2 8.0 4.7e-15 55.4 8.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CEH14731.1 - 1.3e-14 54.7 0.0 4.1e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CEH14731.1 - 0.00023 21.0 0.0 0.00047 20.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CEH14731.1 - 0.013 14.9 2.7 0.025 13.9 2.7 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain WD40 PF00400.32 CEH14733.1 - 1e-61 203.4 14.7 1.6e-09 38.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CEH14733.1 - 2.1e-27 95.2 5.1 3.6e-27 94.5 5.1 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CEH14733.1 - 2.2e-24 85.6 0.2 1.4e-05 25.3 0.0 6.7 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEH14733.1 - 6.8e-10 38.7 0.0 0.036 13.4 0.0 4.6 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 CEH14733.1 - 3.6e-09 36.1 0.6 0.64 8.9 0.0 5.8 2 2 5 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEH14733.1 - 6.7e-06 25.0 0.9 0.51 8.9 0.3 3.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 CEH14733.1 - 0.00012 21.9 0.4 2.7 8.0 0.0 4.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 CEH14733.1 - 0.00029 19.5 0.4 0.079 11.5 0.0 2.8 1 1 0 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.6 CEH14733.1 - 0.0035 16.7 0.9 8.3 5.6 0.0 4.1 2 2 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal GAS PF13851.6 CEH14733.1 - 0.0044 16.4 0.3 0.0075 15.6 0.3 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding CEP63 PF17045.5 CEH14733.1 - 0.025 14.5 2.1 0.039 13.9 2.1 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Clathrin_lg_ch PF01086.17 CEH14733.1 - 0.1 12.7 0.2 0.17 11.9 0.2 1.2 1 0 0 1 1 1 0 Clathrin light chain DUF4402 PF14352.6 CEH14733.1 - 0.11 13.2 0.0 16 6.2 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4402) nos_propeller PF18764.1 CEH14733.1 - 0.13 12.2 0.0 37 4.3 0.0 3.7 3 1 1 4 4 4 0 Nitrous oxide reductase propeller repeat Uso1_p115_C PF04871.13 CEH14733.1 - 0.18 12.2 0.9 0.34 11.3 0.9 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DPPIV_N PF00930.21 CEH14733.1 - 0.2 10.4 0.0 9.4 4.9 0.0 2.7 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region TPX2 PF06886.11 CEH14733.1 - 1.2 9.4 3.2 2.1 8.7 3.2 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Proteasome_A_N PF10584.9 CEH14733.1 - 1.8 8.3 4.6 72 3.2 0.0 4.4 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature AMP-binding PF00501.28 CEH14734.1 - 5.7e-10 38.4 0.1 1.3e-09 37.2 0.0 1.5 1 1 1 2 2 2 1 AMP-binding enzyme GGDEF_2 PF17853.1 CEH14734.1 - 0.073 13.3 1.3 0.72 10.1 0.1 3.1 3 1 1 4 4 4 0 GGDEF-like domain Glyco_hydro_47 PF01532.20 CEH14737.1 - 6.2e-51 173.7 0.0 3e-28 98.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 DUF2236 PF09995.9 CEH14738.1 - 2e-07 31.5 0.0 2.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2236 PF09995.9 CEH14739.1 - 0.0077 16.5 1.1 0.015 15.5 0.1 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) ICMT PF04140.14 CEH14740.1 - 5.6e-15 55.5 0.2 9e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CEH14740.1 - 4.7e-10 39.8 0.4 3.7e-08 33.7 0.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 CEH14740.1 - 0.02 14.4 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Ribosomal_S9 PF00380.19 CEH14741.1 - 2.7e-39 134.4 0.1 5.7e-39 133.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S9/S16 MRFAP1 PF15155.6 CEH14741.1 - 0.091 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 MORF4 family-associated protein1 baeRF_family3 PF18845.1 CEH14741.1 - 0.1 12.9 0.4 0.16 12.2 0.4 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 DUF1706 PF08020.11 CEH14741.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) MafB19-deam PF14437.6 CEH14742.1 - 8.6e-20 70.9 0.0 2e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 CEH14742.1 - 1.7e-19 69.5 0.0 2.9e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 CEH14742.1 - 0.0068 16.5 0.5 0.084 12.9 0.5 2.3 1 1 0 1 1 1 1 Bd3614-like deaminase AID PF18767.1 CEH14742.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Activation induced deaminase RNA_ligase PF09414.10 CEH14744.1 - 4.2e-28 98.7 0.0 7e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 CEH14744.1 - 3.7e-12 46.6 0.2 4.2e-05 23.7 0.0 2.7 1 1 1 2 2 2 2 AAA domain Y_phosphatase PF00102.27 CEH14744.1 - 0.00073 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Zeta_toxin PF06414.12 CEH14744.1 - 0.0061 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.17 CEH14744.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 CEH14744.1 - 0.009 16.3 0.0 0.028 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain DSPc PF00782.20 CEH14744.1 - 0.0096 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain APS_kinase PF01583.20 CEH14744.1 - 0.015 15.2 0.2 6.7 6.6 0.0 2.4 1 1 1 2 2 2 0 Adenylylsulphate kinase 6PF2K PF01591.18 CEH14744.1 - 0.02 14.2 0.0 0.051 12.9 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Y_phosphatase3 PF13350.6 CEH14744.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 CEH14744.1 - 0.088 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) AAA_16 PF13191.6 CEH14744.1 - 0.11 12.9 0.1 2.7 8.4 0.0 2.7 3 0 0 3 3 2 0 AAA ATPase domain AAA_17 PF13207.6 CEH14744.1 - 0.11 12.9 0.0 4.1 7.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain 3HCDH_RFF PF18321.1 CEH14744.1 - 0.71 10.4 2.5 7.6 7.1 0.1 3.1 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain gerPA PF10676.9 CEH14745.1 - 0.001 19.3 10.8 5 7.4 0.1 4.5 3 1 2 5 5 5 3 Spore germination protein gerPA/gerPF Nudix_N_2 PF14803.6 CEH14745.1 - 0.34 10.9 2.1 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal Antimicrobial23 PF16048.5 CEH14746.1 - 0.51 10.1 2.6 1.1 9.0 2.6 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide DUF4226 PF10774.9 CEH14746.1 - 0.6 10.4 3.3 1.8 8.9 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Peptidase_C50 PF03568.17 CEH14747.1 - 1.9e-117 392.8 0.0 3.2e-117 392.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 KptA_kDCL PF18176.1 CEH14747.1 - 0.0033 17.3 0.1 0.01 15.7 0.1 1.9 1 0 0 1 1 1 1 KptA in kinetoplastid DICER domain UCH_1 PF13423.6 CEH14749.1 - 2.6e-61 208.0 0.4 3.9e-61 207.4 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 CEH14749.1 - 7.1e-16 59.2 0.0 2.6e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Exonuclease UCH PF00443.29 CEH14749.1 - 0.00086 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 CEH14749.1 - 0.0089 16.9 5.6 4.2 8.4 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1921 PF09081.10 CEH14749.1 - 0.089 13.0 1.3 0.23 11.7 0.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1921) cobW PF02492.19 CEH14750.1 - 7.9e-35 120.0 1.1 1e-34 119.7 1.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 CEH14750.1 - 0.00084 19.3 0.3 0.0017 18.3 0.1 1.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 CEH14750.1 - 0.008 16.6 0.1 0.0096 16.3 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 CEH14750.1 - 0.017 14.9 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 CEH14750.1 - 0.043 12.8 1.0 0.073 12.0 1.0 1.5 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 CEH14750.1 - 0.06 13.1 0.3 0.16 11.7 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CEH14750.1 - 0.063 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 CEH14750.1 - 0.085 11.9 0.6 0.12 11.4 0.6 1.3 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 CEH14750.1 - 0.1 12.7 0.2 0.16 12.2 0.2 1.5 1 1 0 1 1 1 0 AAA domain ADH_zinc_N_2 PF13602.6 CEH14750.1 - 0.12 13.4 0.0 0.15 13.1 0.0 1.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase cobW PF02492.19 CEH14751.1 - 1.1e-09 38.1 0.1 1.8e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CEH14751.1 - 1.7e-07 31.0 0.1 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain DUF4637 PF15470.6 CEH14751.1 - 0.11 12.3 0.5 0.19 11.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 CEH14751.1 - 7.8 4.5 7.9 11 3.9 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Fer4_15 PF13459.6 CEH14751.1 - 8.4 7.2 9.5 6.7 7.5 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain Sugar_tr PF00083.24 CEH14754.1 - 3.1e-44 151.6 10.3 4.1e-41 141.3 5.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEH14754.1 - 7.2e-20 71.2 21.0 9.1e-11 41.3 5.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily SAPS PF04499.15 CEH14755.1 - 5.1e-136 454.3 0.0 9.7e-136 453.4 0.0 1.5 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Formyl_trans_N PF00551.19 CEH14755.1 - 6.8e-20 71.6 0.0 1.8e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CEH14755.1 - 0.0011 19.1 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain tRNA-synt_1 PF00133.22 CEH14756.1 - 1.2e-210 700.8 0.0 2.4e-209 696.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CEH14756.1 - 1.3e-37 129.1 1.7 1.5e-37 128.9 0.2 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CEH14756.1 - 8.9e-12 44.4 0.1 9.4e-05 21.3 0.0 4.8 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CEH14756.1 - 1.2e-07 31.4 0.8 7.9e-06 25.5 0.0 2.7 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CEH14756.1 - 0.0059 16.0 0.0 0.61 9.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 CEH14756.1 - 0.1 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.25 CEH14756.1 - 0.18 11.1 0.7 0.84 8.9 0.0 2.4 3 1 0 3 3 3 0 tRNA synthetases class I (W and Y) AAA PF00004.29 CEH14757.1 - 1.6e-15 57.7 0.0 2.6e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 CEH14757.1 - 8.9e-12 45.4 0.2 4.2e-11 43.2 0.1 2.0 2 0 0 2 2 2 1 BCS1 N terminal DUF815 PF05673.13 CEH14757.1 - 0.00062 19.0 0.1 0.001 18.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CEH14757.1 - 0.043 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_8 PF12780.7 CEH14757.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_16 PF13191.6 CEH14757.1 - 0.087 13.2 0.0 0.17 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Ank_2 PF12796.7 CEH14758.1 - 8.6e-12 45.5 0.0 1.9e-06 28.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEH14758.1 - 2.2e-09 37.7 0.1 0.00011 22.7 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEH14758.1 - 9.7e-09 35.3 0.1 4.3e-05 23.7 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEH14758.1 - 1.9e-06 28.1 0.1 0.0017 18.7 0.5 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CEH14758.1 - 3.5e-05 23.9 0.1 0.065 13.8 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeat DEAD PF00270.29 CEH14760.1 - 8.4e-44 149.4 0.1 1.2e-43 148.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH14760.1 - 9e-28 96.8 0.5 8.9e-27 93.6 0.3 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH14760.1 - 0.0028 17.7 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CEH14760.1 - 0.04 13.2 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Acetyltransf_1 PF00583.25 CEH14761.1 - 3.3e-14 53.1 0.0 4e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEH14761.1 - 6.8e-06 26.4 0.0 8.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEH14761.1 - 0.00029 20.8 0.0 0.00036 20.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CEH14761.1 - 0.001 19.0 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Malate_synthase PF01274.22 CEH14764.1 - 1.1e-26 93.2 0.0 1.2e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Malate_synthase PF01274.22 CEH14765.1 - 1e-152 509.1 0.0 1.2e-152 508.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 CEH14765.1 - 0.0025 17.0 0.0 0.0038 16.4 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family E3_UFM1_ligase PF09743.9 CEH14765.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 DUF1349 PF07081.11 CEH14766.1 - 5.4e-25 88.1 0.2 6.6e-25 87.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) PH_9 PF15410.6 CEH14767.1 - 7.1e-08 32.8 0.1 1.5e-06 28.6 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CEH14767.1 - 6.6e-07 29.8 0.0 0.021 15.3 0.0 2.4 2 0 0 2 2 2 2 PH domain SDA1 PF05285.12 CEH14767.1 - 0.18 11.2 3.2 0.34 10.3 3.2 1.4 1 0 0 1 1 1 0 SDA1 PH_11 PF15413.6 CEH14767.1 - 0.33 11.4 0.5 3.2 8.2 0.5 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain DNA_pol_phi PF04931.13 CEH14767.1 - 5.2 5.0 8.3 7.4 4.5 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DEAD PF00270.29 CEH14768.1 - 6.8e-43 146.5 0.0 1e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CEH14768.1 - 1.3e-05 25.2 0.0 6.5e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CEH14768.1 - 0.037 13.7 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Pex2_Pex12 PF04757.14 CEH14768.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region DUF2052 PF09747.9 CEH14768.1 - 0.089 12.9 3.2 0.19 11.9 3.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CMS1 PF14617.6 CEH14768.1 - 0.84 8.9 6.9 0.97 8.7 0.0 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit zf-met PF12874.7 CEH14769.1 - 8.5e-06 26.0 0.6 1.5e-05 25.2 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEH14769.1 - 0.00018 21.7 0.2 0.00029 21.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CEH14769.1 - 0.4 11.2 3.0 0.58 10.7 1.3 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Selenoprotein_S PF06936.11 CEH14769.1 - 9.6 6.0 15.6 7.1 6.4 3.4 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) efThoc1 PF11957.8 CEH14770.1 - 4.2e-86 289.6 0.8 2.9e-80 270.3 0.0 2.8 2 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor DUF3446 PF11928.8 CEH14770.1 - 0.03 14.6 12.4 0.075 13.3 12.4 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain TPT PF03151.16 CEH14772.1 - 1.1e-19 70.9 16.9 1.3e-19 70.6 16.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Sec61_beta PF03911.16 CEH14772.1 - 6.1 7.0 10.5 15 5.7 0.6 4.2 3 0 0 3 3 3 0 Sec61beta family Glyco_hydro_2_C PF02836.17 CEH14773.1 - 1.6e-14 53.7 0.0 3.7e-13 49.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 CEH14773.1 - 5.4e-14 52.5 0.1 9.3e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 CEH14773.1 - 8.6e-09 36.0 0.0 2.9e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Exo_endo_phos PF03372.23 CEH14775.1 - 1e-21 77.5 0.0 1e-21 77.5 0.0 2.5 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 CEH14775.1 - 1.4e-07 31.1 1.9 0.00025 20.7 0.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CEH14775.1 - 6.4e-06 26.4 4.3 0.036 14.5 0.4 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) DHO_dh PF01180.21 CEH14777.1 - 1.8e-94 316.3 0.0 2.9e-94 315.6 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase dCache_2 PF08269.11 CEH14777.1 - 0.016 14.4 0.2 0.028 13.6 0.2 1.3 1 0 0 1 1 1 0 Cache domain ApoO PF09769.9 CEH14777.1 - 0.033 14.1 0.8 0.075 13.0 0.8 1.6 1 0 0 1 1 1 0 Apolipoprotein O FMN_dh PF01070.18 CEH14777.1 - 0.14 11.2 3.5 0.32 10.0 1.1 2.6 3 1 0 3 3 3 0 FMN-dependent dehydrogenase UPF0242 PF06785.11 CEH14779.1 - 0.011 15.8 0.6 0.02 15.0 0.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 CEH14779.1 - 0.019 15.6 3.1 0.042 14.5 3.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DivIVA PF05103.13 CEH14779.1 - 0.089 12.9 0.4 0.22 11.6 0.4 1.6 1 0 0 1 1 1 0 DivIVA protein DUF148 PF02520.17 CEH14779.1 - 0.14 12.3 4.3 0.33 11.1 4.3 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 Spc7 PF08317.11 CEH14779.1 - 0.15 10.9 4.3 0.26 10.2 4.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 CEH14779.1 - 0.17 10.5 1.5 0.26 9.9 1.5 1.1 1 0 0 1 1 1 0 AAA domain EzrA PF06160.12 CEH14779.1 - 0.35 9.0 3.8 0.53 8.4 3.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HR1 PF02185.16 CEH14779.1 - 0.37 10.9 6.3 5.9 7.1 2.2 2.8 2 0 0 2 2 2 0 Hr1 repeat TPR_MLP1_2 PF07926.12 CEH14779.1 - 0.39 10.8 5.2 1.2 9.2 5.2 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cluap1 PF10234.9 CEH14779.1 - 0.65 9.3 5.7 1.3 8.4 5.7 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 IFT57 PF10498.9 CEH14779.1 - 0.65 8.9 4.6 1 8.3 4.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Lipoprotein_20 PF13942.6 CEH14779.1 - 0.85 9.5 4.6 1.6 8.6 4.6 1.3 1 0 0 1 1 1 0 YfhG lipoprotein KxDL PF10241.9 CEH14779.1 - 1.3 9.3 4.3 3.6 7.9 4.3 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein Fzo_mitofusin PF04799.13 CEH14779.1 - 1.5 8.4 5.3 3.3 7.3 5.3 1.6 1 0 0 1 1 1 0 fzo-like conserved region DUF1664 PF07889.12 CEH14779.1 - 2.5 8.2 6.2 5.3 7.1 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 CEH14779.1 - 2.9 7.7 13.0 0.18 11.6 6.8 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4665 PF15679.5 CEH14779.1 - 3 8.5 4.3 1.6 9.4 1.7 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4665) DUF773 PF05600.12 CEH14779.1 - 3.4 6.3 6.7 5.3 5.7 6.7 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Methyltransf_23 PF13489.6 CEH14780.1 - 1.9e-07 31.1 0.0 3.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH14780.1 - 1.4e-06 28.9 0.0 0.0051 17.5 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CEH14780.1 - 1.7e-05 25.4 0.0 0.0021 18.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CEH14780.1 - 4.9e-05 24.3 0.1 9.6e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH14780.1 - 0.00023 21.8 0.0 0.001 19.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH14780.1 - 0.00067 19.5 0.0 0.0066 16.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.8 CEH14781.1 - 2.6e-141 471.3 0.0 3.5e-141 470.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 CEH14781.1 - 3.5e-10 40.5 0.0 1.6e-09 38.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH14781.1 - 9.2e-09 35.3 0.0 3.3e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH14781.1 - 6.8e-08 33.1 0.0 7.2e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH14781.1 - 4.3e-07 30.6 0.0 1.5e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH14781.1 - 4e-06 26.7 0.0 1.2e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEH14781.1 - 0.00052 19.4 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CEH14781.1 - 0.00083 18.7 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 CEH14781.1 - 0.009 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 CEH14781.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) adh_short PF00106.25 CEH14783.1 - 9.3e-32 110.1 0.9 1.4e-31 109.5 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH14783.1 - 7.1e-25 87.9 0.4 1.1e-24 87.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH14783.1 - 1.2e-06 28.6 0.3 1.7e-06 28.1 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 CEH14783.1 - 0.019 15.1 0.4 0.051 13.8 0.1 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 CEH14783.1 - 0.13 11.3 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.26 CEH14784.1 - 1.3e-10 41.4 0.0 2.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH14784.1 - 0.23 11.4 0.2 3 7.8 0.1 2.8 3 1 1 4 4 4 0 Alcohol dehydrogenase GroES-like domain FTHFS PF01268.19 CEH14785.1 - 9.8e-260 862.5 0.5 2.1e-259 861.4 0.0 1.7 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CEH14785.1 - 1.2e-63 213.3 1.8 1.2e-63 213.3 1.8 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CEH14785.1 - 1.5e-36 125.2 0.0 6e-36 123.2 0.1 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Prefoldin PF02996.17 CEH14785.1 - 0.01 15.8 0.6 0.066 13.1 0.0 2.5 2 0 0 2 2 2 0 Prefoldin subunit OCD_Mu_crystall PF02423.15 CEH14785.1 - 0.021 13.8 0.3 0.04 12.9 0.3 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Mito_carr PF00153.27 CEH14786.1 - 5.6e-62 205.7 3.7 2.4e-21 75.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GPP34 PF05719.11 CEH14787.1 - 1.2e-67 227.9 0.1 1.4e-67 227.7 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) DUF1488 PF07369.11 CEH14787.1 - 0.053 13.5 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) Complex1_LYR PF05347.15 CEH14788.1 - 7.8e-06 25.8 2.3 1.9e-05 24.6 2.3 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxogl_dehyd_N PF16078.5 CEH14788.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus F-box PF00646.33 CEH14791.1 - 0.0029 17.4 0.3 0.007 16.2 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CEH14791.1 - 0.015 15.2 0.2 0.042 13.8 0.2 1.8 1 0 0 1 1 1 0 F-box-like NAD_binding_2 PF03446.15 CEH14793.1 - 0.028 14.6 0.0 0.031 14.4 0.0 1.0 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F-box PF00646.33 CEH14795.1 - 1.2e-05 25.1 1.0 3.5e-05 23.6 0.3 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CEH14795.1 - 3.4e-05 23.6 0.2 3.4e-05 23.6 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 CEH14796.1 - 8.1e-05 22.4 1.7 0.00017 21.4 0.6 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEH14796.1 - 0.00014 21.6 0.8 0.00027 20.7 0.8 1.6 1 0 0 1 1 1 1 F-box domain DnaT PF17948.1 CEH14798.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 DnaT DNA-binding domain DUF5407 PF17401.2 CEH14798.1 - 0.15 12.4 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5407) F-box-like PF12937.7 CEH14799.1 - 1.9e-08 34.1 0.1 3.6e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEH14799.1 - 3.7e-06 26.7 0.0 1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain RVT_2 PF07727.14 CEH14800.1 - 8.7e-53 179.4 0.0 1.2e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_6 PF13964.6 CEH14800.1 - 0.12 12.7 0.1 0.95 9.9 0.0 2.4 2 1 0 2 2 2 0 Kelch motif Retrotran_gag_2 PF14223.6 CEH14801.1 - 9.5e-12 44.8 0.0 1.2e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type eIF3g PF12353.8 CEH14801.1 - 0.035 14.5 0.2 0.064 13.6 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Dioxygenase_N PF04444.14 CEH14801.1 - 0.056 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Cullin_binding PF03556.15 CEH14801.1 - 0.12 12.8 0.2 0.19 12.2 0.2 1.3 1 0 0 1 1 1 0 Cullin binding F-box PF00646.33 CEH14802.1 - 0.0028 17.5 0.2 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 F-box domain DMA PF03474.14 CEH14803.1 - 0.018 14.6 0.1 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif Retrotran_gag_2 PF14223.6 CEH14805.1 - 4.1e-16 58.9 0.0 7.1e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CEH14805.1 - 1.4e-07 31.3 0.0 3.8e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_3 PF14244.6 CEH14805.1 - 1.1e-06 28.3 0.2 2.2e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVT_2 PF07727.14 CEH14805.1 - 5e-05 23.1 0.0 8.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4219 PF13961.6 CEH14805.1 - 0.0031 17.1 0.7 0.036 13.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) zf-CCHC_4 PF14392.6 CEH14805.1 - 0.37 10.5 2.0 0.8 9.5 2.0 1.6 1 0 0 1 1 1 0 Zinc knuckle F-box PF00646.33 CEH14806.1 - 0.04 13.8 1.4 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 CEH14806.1 - 0.23 11.4 0.1 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 F-box-like PWI PF01480.17 CEH14807.1 - 0.00029 21.1 0.0 0.00066 20.0 0.0 1.5 1 0 0 1 1 1 1 PWI domain ETF_alpha PF00766.19 CEH14807.1 - 1 9.4 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain SPT16 PF08644.11 CEH14807.1 - 1.7 8.8 3.5 1.2 9.3 0.6 2.2 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Med4 PF10018.9 CEH14808.1 - 2.1e-07 30.8 2.5 2.1e-07 30.8 2.5 1.5 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 HeLo PF14479.6 CEH14808.1 - 1.4 8.7 8.0 0.036 13.9 1.7 1.5 2 0 0 2 2 2 0 Prion-inhibition and propagation FlgN PF05130.12 CEH14808.1 - 2 8.9 7.2 0.13 12.8 0.9 2.2 2 1 1 3 3 3 0 FlgN protein NotI PF12183.8 CEH14809.1 - 0.06 12.7 0.3 0.061 12.7 0.3 1.1 1 0 0 1 1 1 0 Restriction endonuclease NotI F-box-like PF12937.7 CEH14810.1 - 1.3e-05 25.0 0.0 4e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEH14810.1 - 0.001 18.9 0.1 0.0046 16.8 0.0 2.1 2 0 0 2 2 2 1 F-box domain CBM65_1 PF18259.1 CEH14810.1 - 0.058 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding module 65 domain 1 DUF2140 PF09911.9 CEH14810.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) F-box-like PF12937.7 CEH14811.1 - 0.00018 21.3 0.2 0.00042 20.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEH14812.1 - 6e-05 22.8 0.7 0.00013 21.7 0.7 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEH14812.1 - 0.0085 16.0 0.7 0.0085 16.0 0.7 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEH14813.1 - 0.00041 20.2 0.4 0.0011 18.8 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEH14813.1 - 0.0077 16.1 0.4 0.016 15.1 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEH14814.1 - 1.4e-05 24.8 0.7 1.4e-05 24.8 0.7 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 CEH14814.1 - 0.00013 21.8 0.2 0.00013 21.8 0.2 2.2 3 0 0 3 3 3 1 F-box-like Chorion_1 PF01723.16 CEH14814.1 - 0.16 11.9 0.2 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Chorion protein F-box-like PF12937.7 CEH14816.1 - 5.2e-07 29.5 0.5 1.2e-06 28.3 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEH14816.1 - 1.3e-05 24.9 0.6 4.6e-05 23.2 0.6 2.0 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 CEH14819.1 - 4.1e-09 36.9 0.4 0.00066 20.4 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH14819.1 - 9.8e-06 25.8 0.0 2.5 8.5 0.0 3.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain G-patch PF01585.23 CEH14822.1 - 5.9e-10 38.9 1.4 1.1e-09 38.0 1.4 1.4 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CEH14822.1 - 0.034 14.0 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 CEH14823.1 - 1.4e-22 80.2 46.4 2.2e-16 59.8 27.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GDWWSH PF15667.5 CEH14824.1 - 0.26 10.7 1.5 5.6 6.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function with motif GDWWSH Gtr1_RagA PF04670.12 CEH14826.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF4632 PF15451.6 CEH14828.1 - 0.017 15.2 0.2 0.03 14.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) CIA30 PF08547.12 CEH14831.1 - 6.9e-12 45.7 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) PX PF00787.24 CEH14832.1 - 0.0094 15.9 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 PX domain Hexapep PF00132.24 CEH14833.1 - 4.4e-13 48.4 8.3 2.5e-05 23.8 0.9 4.7 2 2 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) W2 PF02020.18 CEH14833.1 - 0.0017 18.5 0.4 0.0017 18.5 0.4 2.3 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep_2 PF14602.6 CEH14833.1 - 0.0024 17.6 5.9 0.64 9.8 1.6 3.2 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CEH14833.1 - 0.0075 14.4 0.4 0.011 13.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 CEH14833.1 - 0.017 14.1 0.3 0.027 13.4 0.3 1.2 1 0 0 1 1 1 0 L-fucokinase Nse4_C PF08743.10 CEH14834.1 - 2.3e-29 101.5 0.1 9.7e-29 99.5 0.0 2.1 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 CEH14834.1 - 4.5e-12 45.9 0.8 1.2e-11 44.6 0.8 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF3762 PF12591.8 CEH14834.1 - 0.064 13.5 0.6 0.13 12.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) DUF3140 PF11338.8 CEH14835.1 - 1.7e-34 118.1 1.6 2e-34 117.9 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) DUF1843 PF08898.10 CEH14835.1 - 0.01 16.3 0.2 0.017 15.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Aminotran_1_2 PF00155.21 CEH14836.1 - 1.2e-30 107.0 0.0 3.3e-19 69.3 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II PseudoU_synth_1 PF01416.20 CEH14837.1 - 2.9e-11 43.8 0.0 1.2e-09 38.6 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF1688 PF07958.11 CEH14838.1 - 1.2e-156 521.7 0.0 1.4e-156 521.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) WD40 PF00400.32 CEH14839.1 - 8.6e-10 39.1 5.1 0.047 14.6 0.1 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat tRNA_synthFbeta PF17759.1 CEH14841.1 - 6.4e-43 146.7 0.0 8.9e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CEH14841.1 - 2.1e-30 104.8 0.1 2.4e-29 101.4 0.0 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CEH14841.1 - 6.1e-23 81.4 0.0 1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CEH14841.1 - 2.8e-19 69.2 0.0 2.1e-17 63.2 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 CEH14841.1 - 0.02 14.4 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Herpes_V23 PF01802.17 CEH14841.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Tfb4 PF03850.14 CEH14842.1 - 1e-57 195.8 8.4 6.3e-57 193.2 8.4 1.8 1 1 0 1 1 1 1 Transcription factor Tfb4 Bd3614-deam PF14439.6 CEH14842.1 - 0.011 15.8 1.2 0.039 14.0 1.2 2.0 1 0 0 1 1 1 0 Bd3614-like deaminase AAA_assoc_2 PF16193.5 CEH14842.1 - 0.048 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA C-terminal domain zf-HIT PF04438.16 CEH14842.1 - 9.7 6.2 10.6 26 4.8 4.6 2.3 2 0 0 2 2 2 0 HIT zinc finger HNH_2 PF13391.6 CEH14843.1 - 4.2e-05 23.6 0.0 0.00015 21.8 0.0 1.9 1 1 0 1 1 1 1 HNH endonuclease LSM14 PF12701.7 CEH14846.1 - 7.8e-22 77.2 0.0 1.2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CEH14846.1 - 1.3e-08 35.7 0.1 0.00022 22.0 0.1 2.6 2 0 0 2 2 2 2 FDF domain SM-ATX PF14438.6 CEH14846.1 - 5.8e-05 23.1 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain CENP-I PF07778.11 CEH14847.1 - 1.7e-12 46.9 0.0 9e-09 34.6 0.0 3.0 3 0 0 3 3 3 2 Mis6 HSP70 PF00012.20 CEH14849.1 - 2.6e-255 848.3 4.5 2.9e-255 848.1 4.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEH14849.1 - 6e-15 54.9 0.1 1.7e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 CEH14849.1 - 0.011 15.0 0.1 0.027 13.7 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.6 CEH14849.1 - 0.023 15.1 2.2 15 6.0 0.1 3.5 3 2 0 3 3 3 0 Cell division protein FtsA FGGY_C PF02782.16 CEH14849.1 - 0.023 14.4 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 CEH14849.1 - 0.039 13.5 0.0 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family RNA_GG_bind PF10258.9 CEH14849.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 PHAX RNA-binding domain Borrelia_P83 PF05262.11 CEH14851.1 - 1.4 7.4 25.3 0.71 8.3 12.8 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein DUF3807 PF12720.7 CEH14851.1 - 1.9 8.7 29.6 2.6 8.3 8.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.12 CEH14851.1 - 2.8 7.7 26.3 3 7.6 8.2 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 GATase_2 PF00310.21 CEH14852.1 - 2e-173 577.0 0.0 2.6e-173 576.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CEH14852.1 - 1.2e-154 515.0 0.2 2.6e-154 513.8 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CEH14852.1 - 7.8e-115 383.2 0.0 6.2e-114 380.2 0.0 2.0 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CEH14852.1 - 1e-85 286.2 2.1 1.8e-85 285.3 2.1 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 CEH14852.1 - 1.3e-26 93.5 0.1 8.6e-26 90.8 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CEH14852.1 - 3e-22 78.5 0.0 6.4e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 CEH14852.1 - 1.5e-09 38.0 0.1 5.9e-09 36.0 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CEH14852.1 - 8.9e-07 28.5 1.0 2.2e-06 27.2 0.1 2.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 CEH14852.1 - 1.2e-06 29.0 1.9 0.00032 21.2 0.1 3.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEH14852.1 - 6.9e-06 25.5 0.6 0.019 14.2 0.0 4.1 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEH14852.1 - 1.2e-05 24.2 0.2 5.8e-05 22.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 CEH14852.1 - 1.3e-05 24.9 0.8 0.0013 18.4 0.3 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CEH14852.1 - 4.2e-05 23.1 0.6 8.2e-05 22.1 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEH14852.1 - 0.00021 20.5 0.3 0.00051 19.3 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CEH14852.1 - 0.00063 19.1 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 CEH14852.1 - 0.002 18.5 0.0 2.4 8.6 0.0 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 CEH14852.1 - 0.0028 16.7 0.2 0.32 10.0 0.1 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein AdoHcyase_NAD PF00670.21 CEH14852.1 - 0.0049 17.0 0.6 4.9 7.2 0.1 2.7 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMN_dh PF01070.18 CEH14852.1 - 0.0055 15.8 3.0 0.0078 15.3 1.6 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Thi4 PF01946.17 CEH14852.1 - 0.015 14.6 0.1 0.04 13.2 0.1 1.7 1 0 0 1 1 1 0 Thi4 family GATase_6 PF13522.6 CEH14852.1 - 0.023 14.9 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_binding_9 PF13454.6 CEH14852.1 - 0.044 13.8 0.1 0.91 9.5 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 CEH14852.1 - 0.089 12.2 0.1 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEH14852.1 - 0.11 11.7 0.6 9.5 5.4 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CEH14852.1 - 0.49 9.4 2.9 0.34 9.9 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Peptidase_M3 PF01432.20 CEH14853.1 - 4.2e-133 445.0 0.0 5.7e-133 444.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 CEH14853.1 - 0.14 12.4 0.8 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 Effector protein Peptidase_M50B PF13398.6 CEH14853.1 - 0.21 11.2 0.2 0.37 10.4 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Sporozoite_P67 PF05642.11 CEH14854.1 - 0.13 10.3 7.0 0.019 13.1 2.1 2.0 1 1 0 2 2 2 0 Sporozoite P67 surface antigen Peptidase_M18 PF02127.15 CEH14854.1 - 0.21 10.4 0.3 0.31 9.8 0.3 1.2 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) CDC27 PF09507.10 CEH14854.1 - 5.9 6.2 9.6 3 7.1 2.9 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Peptidase_S24 PF00717.23 CEH14855.1 - 6.5e-08 32.4 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Cys_Met_Meta_PP PF01053.20 CEH14856.1 - 1.3e-152 507.8 0.0 1.4e-152 507.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CEH14856.1 - 2.1e-11 43.8 0.1 5.7e-11 42.3 0.1 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CEH14856.1 - 7.9e-11 41.7 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CEH14856.1 - 5.6e-10 38.7 0.1 8.1e-10 38.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CEH14856.1 - 8.3e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 CEH14856.1 - 0.0044 15.6 0.0 0.0056 15.3 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 CEH14856.1 - 0.0049 15.6 0.0 0.007 15.1 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDC-P PF02347.16 CEH14856.1 - 0.04 12.7 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Asparaginase_C PF17763.1 CEH14856.1 - 0.055 13.7 0.0 0.46 10.7 0.0 2.3 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain Zn_clus PF00172.18 CEH14858.1 - 2.2e-09 37.3 12.9 3.8e-09 36.5 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CEH14858.1 - 0.009 15.1 0.0 0.021 13.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain JmjC PF02373.22 CEH14859.1 - 2e-38 131.3 0.2 4.4e-38 130.2 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CEH14859.1 - 1.1e-14 54.1 0.2 3.8e-14 52.4 0.2 2.0 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.6 CEH14859.1 - 2.6e-11 43.7 0.6 6.4e-11 42.4 0.1 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CEH14859.1 - 1.1e-10 41.6 1.0 2.5e-10 40.5 0.1 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain Cellulase PF00150.18 CEH14860.1 - 5.2e-17 62.2 3.3 8.1e-17 61.6 3.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.22 CEH14861.1 - 1.9e-41 142.3 0.0 3.1e-41 141.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 CEH14862.1 - 2e-17 63.7 0.0 6.2e-14 52.3 0.0 2.6 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH14862.1 - 6e-05 23.7 0.5 0.00029 21.5 0.2 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family HLH PF00010.26 CEH14863.1 - 0.00093 19.1 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Lzipper-MIP1 PF14389.6 CEH14863.1 - 0.033 14.5 1.9 0.07 13.4 0.3 2.2 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1722 PF08349.11 CEH14863.1 - 0.23 11.8 0.0 0.45 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) MFS_1 PF07690.16 CEH14865.1 - 4.5e-35 121.2 21.3 4.5e-35 121.2 21.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH14865.1 - 7e-14 51.5 3.6 7e-14 51.5 3.6 2.1 3 1 0 3 3 3 1 Sugar (and other) transporter AA_kinase PF00696.28 CEH14866.1 - 1.5e-25 90.2 0.2 2.7e-24 86.1 0.2 2.3 1 1 0 1 1 1 1 Amino acid kinase family Cys_Met_Meta_PP PF01053.20 CEH14867.1 - 2.9e-131 437.5 0.0 3.4e-131 437.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CEH14867.1 - 1.8e-11 43.6 0.0 2.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CEH14867.1 - 4.4e-08 32.8 0.1 4.5e-07 29.5 0.0 2.3 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CEH14867.1 - 1e-07 31.5 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CEH14867.1 - 0.0071 15.7 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 CEH14867.1 - 0.06 11.9 0.1 0.093 11.2 0.1 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase ATP_bind_1 PF03029.17 CEH14868.1 - 2.3e-63 214.2 0.0 2.7e-55 187.8 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 CEH14868.1 - 0.013 15.2 0.1 0.031 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CEH14868.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 CEH14868.1 - 0.08 11.9 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CEH14868.1 - 0.091 12.9 0.2 1.1 9.4 0.2 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 CEH14868.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 CEH14868.1 - 0.14 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain LSM PF01423.22 CEH14869.1 - 1.3e-17 63.2 0.0 1.6e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEH14869.1 - 0.00017 21.6 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CEH14869.1 - 0.042 14.0 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain RVT_2 PF07727.14 CEH14870.1 - 3.3e-55 187.4 0.0 5e-55 186.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CEH14870.1 - 8.2e-22 77.4 0.0 1.9e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 CEH14870.1 - 1.2e-16 60.9 0.0 3.6e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CEH14870.1 - 7.4e-11 41.7 0.6 1.5e-10 40.8 0.6 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 CEH14870.1 - 0.00019 21.0 0.5 0.00059 19.4 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 CEH14870.1 - 0.06 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain bZIP_1 PF00170.21 CEH14870.1 - 0.17 12.0 3.2 0.43 10.7 3.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor zf-CCHC_5 PF14787.6 CEH14870.1 - 0.61 9.9 4.8 0.15 11.8 1.1 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DFP PF04127.15 CEH14873.1 - 0.00014 21.8 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DFP PF04127.15 CEH14874.1 - 0.0021 17.9 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein HlyD PF00529.20 CEH14874.1 - 0.081 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 HlyD membrane-fusion protein of T1SS COX7a PF02238.15 CEH14875.1 - 3.2e-18 65.9 0.7 3.6e-18 65.7 0.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII TrmO_C PF18389.1 CEH14875.1 - 0.028 14.5 0.5 0.036 14.2 0.5 1.2 1 0 0 1 1 1 0 TrmO C-terminal domain GFO_IDH_MocA PF01408.22 CEH14876.1 - 6.6e-14 52.8 0.0 1.1e-13 52.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CEH14876.1 - 1.4e-08 34.7 0.0 2.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 CEH14876.1 - 0.00012 22.7 0.0 0.00022 21.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Peptidase_S10 PF00450.22 CEH14877.1 - 5.1e-71 240.3 0.0 6.4e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Zn_clus PF00172.18 CEH14880.1 - 4e-06 26.8 12.0 4e-06 26.8 12.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOZART1 PF12554.8 CEH14881.1 - 1.8e-13 50.0 0.1 2.2e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SSF PF00474.17 CEH14882.1 - 1.1e-12 47.5 30.7 3.1e-09 36.2 22.6 2.5 1 1 1 2 2 2 2 Sodium:solute symporter family 7tm_7 PF08395.12 CEH14882.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.6 3 1 1 4 4 4 0 7tm Chemosensory receptor YqeY PF09424.10 CEH14883.1 - 2e-30 105.7 4.9 2.5e-30 105.4 4.9 1.1 1 0 0 1 1 1 1 Yqey-like protein Apolipo_F PF15148.6 CEH14883.1 - 0.00069 19.2 1.2 0.00089 18.8 0.7 1.3 1 1 0 1 1 1 1 Apolipoprotein F GatB_Yqey PF02637.18 CEH14883.1 - 0.055 13.3 3.5 0.14 12.1 3.5 1.8 1 1 0 1 1 1 0 GatB domain IKKbetaNEMObind PF12179.8 CEH14883.1 - 0.056 13.5 0.2 2.9 8.0 0.1 2.6 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Tn7_Tnp_TnsA_C PF08721.11 CEH14883.1 - 0.15 12.7 0.2 2.4 8.9 0.0 2.5 2 1 1 3 3 3 0 TnsA endonuclease C terminal Dak2 PF02734.17 CEH14883.1 - 0.39 10.6 8.3 0.17 11.8 0.9 2.1 1 1 1 2 2 2 0 DAK2 domain ATE_C PF04377.15 CEH14884.1 - 3.1e-47 160.6 0.0 5e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CEH14884.1 - 2.6e-28 98.2 1.1 6.1e-28 97.0 1.1 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus SLX9 PF15341.6 CEH14885.1 - 0.16 12.4 2.6 0.25 11.7 1.9 1.7 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF737 PF05300.11 CEH14885.1 - 0.29 11.5 3.3 0.55 10.5 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) tRNA_int_endo PF01974.17 CEH14886.1 - 6.8e-14 51.7 0.0 2.2e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain COG4 PF08318.12 CEH14887.1 - 2.6e-87 293.1 0.0 4e-87 292.4 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein Fzo_mitofusin PF04799.13 CEH14887.1 - 0.027 14.0 0.7 0.42 10.1 0.1 2.6 2 0 0 2 2 2 0 fzo-like conserved region HSCB_C PF07743.13 CEH14887.1 - 5.4 7.6 12.4 55 4.4 8.2 3.7 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain GDP_Man_Dehyd PF16363.5 CEH14888.1 - 4.2e-49 167.7 0.0 5.2e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEH14888.1 - 9.7e-46 156.2 0.0 1.5e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CEH14888.1 - 6.9e-11 41.8 0.0 9.9e-07 28.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 CEH14888.1 - 2e-09 36.8 0.0 3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CEH14888.1 - 5.1e-07 29.1 0.0 7.9e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CEH14888.1 - 1.2e-06 27.9 0.0 0.00055 19.2 0.0 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 CEH14888.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase tRNA-synt_1c PF00749.21 CEH14889.1 - 1.6e-83 280.2 0.2 3.6e-83 279.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain DLIC PF05783.11 CEH14891.1 - 3.4e-48 164.7 0.2 1.9e-32 112.7 0.0 5.9 6 0 0 6 6 6 4 Dynein light intermediate chain (DLIC) AAA PF00004.29 CEH14891.1 - 0.00034 21.0 0.1 0.00072 20.0 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEH14891.1 - 0.00044 20.7 0.2 0.0023 18.3 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEH14891.1 - 0.0012 19.1 0.1 0.014 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CEH14891.1 - 0.019 15.2 0.1 0.07 13.4 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CEH14891.1 - 0.033 14.5 0.1 0.076 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CEH14891.1 - 0.033 13.9 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CEH14891.1 - 0.034 13.5 0.0 0.63 9.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 CEH14891.1 - 0.035 14.1 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 CEH14891.1 - 0.036 13.3 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 CEH14891.1 - 0.039 13.5 0.2 0.16 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CEH14891.1 - 0.056 12.8 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 CEH14891.1 - 0.098 12.4 1.4 0.21 11.3 0.2 2.1 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 CEH14891.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 CEH14891.1 - 0.13 12.8 0.2 0.34 11.4 0.2 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CEH14891.1 - 0.14 12.4 0.7 0.37 11.0 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CEH14891.1 - 0.17 12.5 0.0 0.47 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 CEH14891.1 - 0.19 11.3 0.0 9.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain HAT_KAT11 PF08214.11 CEH14892.1 - 6.3e-31 107.9 0.0 2.2e-30 106.2 0.0 1.7 1 1 0 1 1 1 1 Histone acetylation protein zf-CHCC PF10276.9 CEH14893.1 - 1.6e-18 66.5 1.2 2.3e-18 65.9 1.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf-RING_2 PF13639.6 CEH14895.1 - 8.8e-08 32.4 5.9 1.6e-06 28.3 2.2 2.5 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CEH14895.1 - 1.6e-06 27.8 1.6 1.6e-06 27.8 1.6 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEH14895.1 - 6.5e-06 26.3 1.0 6.5e-06 26.3 1.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEH14895.1 - 6.9e-06 25.8 0.6 6.9e-06 25.8 0.6 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEH14895.1 - 1.4e-05 24.9 5.0 2.9e-05 23.8 1.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEH14895.1 - 0.0003 20.6 4.7 0.00047 20.0 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH14895.1 - 0.0011 18.8 3.3 0.0038 17.1 1.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEH14895.1 - 0.0071 16.4 0.4 0.014 15.4 0.1 1.6 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Elong_Iki1 PF10483.9 CEH14895.1 - 0.0098 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Elongator subunit Iki1 Zn_ribbon_17 PF17120.5 CEH14895.1 - 0.011 15.3 2.6 0.025 14.2 2.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CEH14895.1 - 0.016 14.9 4.3 0.1 12.3 0.3 3.0 3 0 0 3 3 3 0 RING-like zinc finger zf-P11 PF03854.14 CEH14895.1 - 0.016 14.8 0.8 0.016 14.8 0.8 1.7 2 0 0 2 2 2 0 P-11 zinc finger Rad50_zn_hook PF04423.14 CEH14895.1 - 0.026 14.4 1.2 0.049 13.5 0.2 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif SUR7 PF06687.12 CEH14895.1 - 0.03 13.9 0.0 0.08 12.6 0.0 1.6 1 1 0 1 1 1 0 SUR7/PalI family zf-RING_UBOX PF13445.6 CEH14895.1 - 0.032 14.2 7.8 0.095 12.7 1.9 3.1 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.6 CEH14895.1 - 0.17 11.7 3.5 0.074 12.9 0.6 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 CEH14895.1 - 0.18 12.1 1.5 0.42 11.0 1.5 1.6 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 CEH14895.1 - 0.4 10.9 5.2 0.85 9.8 2.9 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-AN1 PF01428.16 CEH14896.1 - 3.1e-16 59.2 30.4 3.1e-09 36.8 8.7 2.5 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CEH14896.1 - 0.0029 17.9 4.5 0.0029 17.9 4.5 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain 4HBT PF03061.22 CEH14897.1 - 2e-09 37.6 0.1 3.8e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 CEH14897.1 - 0.0024 18.2 0.8 0.0045 17.3 0.1 1.7 2 0 0 2 2 2 1 Thioesterase-like superfamily Ribosomal_L36e PF01158.18 CEH14898.1 - 5.7e-36 122.6 6.3 6.6e-36 122.4 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.6 CEH14898.1 - 0.092 12.9 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pinin_SDK_memA PF04696.13 CEH14898.1 - 0.66 10.0 7.0 0.17 11.9 3.7 1.7 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region L51_S25_CI-B8 PF05047.16 CEH14899.1 - 3.4e-12 46.1 0.0 4.4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Prok_Ub PF14454.6 CEH14899.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic Ubiquitin FAD_binding_3 PF01494.19 CEH14900.1 - 1.7e-53 182.1 0.1 2e-52 178.6 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 CEH14900.1 - 6e-18 65.4 0.0 1.9e-17 63.8 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 CEH14900.1 - 4.9e-06 26.4 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CEH14900.1 - 1.2e-05 24.2 0.0 1.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 CEH14900.1 - 1.9e-05 23.9 0.3 5e-05 22.6 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CEH14900.1 - 2e-05 24.0 0.0 4.2e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEH14900.1 - 5.7e-05 23.3 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CEH14900.1 - 0.00027 20.3 0.1 0.00047 19.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 CEH14900.1 - 0.00059 19.2 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CEH14900.1 - 0.0033 16.5 0.2 0.0052 15.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 CEH14900.1 - 0.0083 15.0 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.7 CEH14900.1 - 0.016 14.6 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEH14900.1 - 0.017 15.1 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 CEH14900.1 - 0.021 15.4 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEH14900.1 - 0.066 12.3 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 CEH14900.1 - 0.18 11.4 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2457 PF10446.9 CEH14901.1 - 0.23 10.6 1.4 0.23 10.6 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PTPlike_phytase PF14566.6 CEH14902.1 - 0.00094 19.3 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 CEH14902.1 - 0.00098 18.9 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CEH14902.1 - 0.0022 18.0 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEH14902.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase E1-E2_ATPase PF00122.20 CEH14903.1 - 2.3e-41 141.3 1.7 2.3e-41 141.3 1.7 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEH14903.1 - 8.9e-35 120.0 14.2 3.3e-33 114.9 3.8 3.2 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CEH14903.1 - 4.3e-17 63.1 0.7 2.6e-15 57.3 0.7 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEH14903.1 - 3.8e-13 48.9 0.0 9.5e-13 47.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEH14903.1 - 5.8e-09 35.9 0.0 1.4e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEH14903.1 - 7.5e-05 22.6 0.3 0.00013 21.8 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 CEH14903.1 - 0.17 11.7 0.0 0.17 11.7 0.0 3.6 3 1 1 4 4 4 0 Predicted membrane protein (DUF2157) Iron_permease PF04120.12 CEH14903.1 - 0.52 10.1 2.4 1.4 8.7 2.4 1.7 1 0 0 1 1 1 0 Low affinity iron permease Transket_pyr PF02779.24 CEH14905.1 - 2.9e-32 111.8 0.1 4.9e-32 111.0 0.0 1.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CEH14905.1 - 9.9e-23 80.4 0.0 1.6e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aldo_ket_red PF00248.21 CEH14906.1 - 1.3e-46 159.1 0.0 8.6e-46 156.5 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L10 PF00466.20 CEH14906.1 - 3.6e-05 23.8 0.0 0.00016 21.7 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L10 Herpes_UL6 PF01763.16 CEH14906.1 - 0.014 14.0 0.0 0.023 13.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Anophelin PF10731.9 CEH14907.1 - 0.38 10.6 1.6 1.3 9.0 1.6 1.9 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito FliT PF05400.13 CEH14907.1 - 4.3 8.2 8.2 0.71 10.7 0.1 2.8 3 0 0 3 3 3 0 Flagellar protein FliT Dna2 PF08696.11 CEH14908.1 - 6.2e-25 88.2 0.0 4.2e-19 69.2 0.0 2.9 3 0 0 3 3 3 2 DNA replication factor Dna2 Myc_target_1 PF15179.6 CEH14908.1 - 0.45 10.4 8.8 0.85 9.5 8.8 1.4 1 0 0 1 1 1 0 Myc target protein 1 AAA_11 PF13086.6 CEH14909.1 - 1.4e-37 130.0 0.4 2.5e-18 66.8 0.1 2.0 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CEH14909.1 - 6.7e-17 61.8 0.0 1.3e-16 60.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH14909.1 - 1.8e-12 47.8 0.0 2.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CEH14909.1 - 2.1e-06 27.6 0.1 0.033 13.9 0.0 2.1 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 CEH14909.1 - 2.7e-05 23.9 0.3 5.6e-05 22.8 0.2 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CEH14909.1 - 4.2e-05 24.0 0.0 6.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.14 CEH14909.1 - 5.2e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 1 0 1 1 1 1 Helicase AAA_22 PF13401.6 CEH14909.1 - 0.0005 20.3 0.1 0.00092 19.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CEH14909.1 - 0.00065 19.3 0.0 0.0011 18.5 0.0 1.4 1 1 0 1 1 1 1 P-loop containing dynein motor region UvrD-helicase PF00580.21 CEH14909.1 - 0.00072 19.2 0.2 0.0015 18.1 0.1 1.5 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain MeaB PF03308.16 CEH14909.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CEH14909.1 - 0.003 18.1 0.0 0.0046 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 CEH14909.1 - 0.0041 16.4 0.0 0.079 12.1 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_5 PF07728.14 CEH14909.1 - 0.0041 17.1 0.0 0.0075 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MobB PF03205.14 CEH14909.1 - 0.0042 17.0 0.1 0.0072 16.2 0.1 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.9 CEH14909.1 - 0.0047 15.9 0.1 0.0092 14.9 0.1 1.5 1 1 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_31 PF13614.6 CEH14909.1 - 0.0057 16.6 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEH14909.1 - 0.0062 16.7 0.0 0.0098 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CEH14909.1 - 0.0076 16.7 0.4 0.014 15.8 0.4 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CEH14909.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CEH14909.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.9 CEH14909.1 - 0.015 14.6 0.0 0.047 12.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 CEH14909.1 - 0.016 14.2 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 CEH14909.1 - 0.017 15.1 0.0 0.044 13.8 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 CEH14909.1 - 0.018 15.1 0.4 0.033 14.2 0.4 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TsaE PF02367.17 CEH14909.1 - 0.047 13.7 0.1 0.37 10.8 0.1 2.1 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 CEH14909.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 CEH14909.1 - 0.077 12.8 0.1 0.25 11.1 0.1 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 CEH14909.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CEH14909.1 - 0.095 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CEH14909.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thioredoxin_16 PF18569.1 CEH14909.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain PEPCK_ATP PF01293.20 CEH14909.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Zeta_toxin PF06414.12 CEH14909.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin 6PF2K PF01591.18 CEH14909.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.27 CEH14909.1 - 0.17 12.4 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter KTI12 PF08433.10 CEH14909.1 - 0.2 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_12 PF13087.6 CEH14910.1 - 1.2e-24 87.0 0.3 1.7e-24 86.6 0.3 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 CEH14910.1 - 0.031 13.6 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Atx10homo_assoc PF09759.9 CEH14911.1 - 5.7e-05 23.1 0.0 0.0021 18.1 0.0 3.1 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain CcdA PF07362.12 CEH14912.1 - 0.077 13.4 1.4 13 6.3 0.3 2.3 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA UCH_C PF18031.1 CEH14912.1 - 0.2 11.6 0.6 0.42 10.5 0.6 1.5 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases DUF3040 PF11239.8 CEH14912.1 - 6.4 7.1 5.6 0.59 10.4 0.3 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) DBR1 PF05011.13 CEH14913.1 - 1.6e-33 116.1 0.0 4e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CEH14913.1 - 2e-07 31.7 0.2 3.2e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEH14913.1 - 0.019 15.2 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Cation_ATPase_C PF00689.21 CEH14914.1 - 1.8e-47 161.4 17.9 2.2e-40 138.3 4.1 2.8 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CEH14914.1 - 1.6e-39 135.3 0.1 4.5e-39 133.8 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CEH14914.1 - 1.8e-20 72.8 0.0 4.4e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEH14914.1 - 8.6e-17 62.1 0.5 4.7e-15 56.5 0.5 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEH14914.1 - 5.9e-09 35.5 0.4 5.9e-08 32.3 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEH14914.1 - 0.0043 16.8 0.7 0.058 13.1 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Oxidored_q3 PF00499.20 CEH14914.1 - 0.045 13.5 1.6 0.72 9.6 0.1 2.8 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Cyclin_N PF00134.23 CEH14915.1 - 1.4e-08 34.5 0.0 3e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CEH14915.1 - 0.009 16.4 0.1 0.026 14.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin C-terminal domain XPG_I PF00867.18 CEH14917.1 - 2.3e-25 88.8 0.0 5.3e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CEH14917.1 - 3e-23 82.2 0.0 6e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CEH14917.1 - 9.9e-06 25.2 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 CEH14917.1 - 0.026 15.1 0.0 0.093 13.3 0.0 2.0 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 CEH14917.1 - 0.063 13.9 0.1 3.6 8.3 0.0 2.6 2 1 0 2 2 2 0 Helix-hairpin-helix domain ATP-synt_C PF00137.21 CEH14918.1 - 3.1e-30 104.3 30.7 7.4e-17 61.5 11.7 3.0 3 0 0 3 3 3 2 ATP synthase subunit C Insulin_TMD PF17870.1 CEH14918.1 - 6.6 6.9 6.6 1.5 9.0 0.6 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment NOC3p PF07540.11 CEH14919.1 - 1.2e-26 93.0 0.0 3.3e-26 91.6 0.0 1.8 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 CEH14919.1 - 1.1e-12 48.3 0.9 3.1e-12 46.8 0.1 2.2 2 0 0 2 2 2 1 CBF/Mak21 family Mito_carr PF00153.27 CEH14923.1 - 1.2e-30 105.2 1.1 4.6e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Peptidase_C13 PF01650.18 CEH14924.1 - 2.1e-42 145.4 0.1 2.7e-42 145.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family MFS_1 PF07690.16 CEH14927.1 - 1.9e-23 83.0 19.3 1.6e-11 43.8 5.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily MMS22L_N PF14910.6 CEH14928.1 - 0.021 13.3 0.0 0.026 13.0 0.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal Pyr_redox_2 PF07992.14 CEH14929.1 - 5.9e-27 94.7 0.1 2.1e-15 56.7 0.0 4.1 4 0 0 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEH14929.1 - 4.4e-15 56.0 0.1 4.8e-11 43.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEH14929.1 - 0.00022 20.5 0.1 0.0089 15.2 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 CEH14929.1 - 0.0042 16.0 0.0 4.9 5.9 0.0 3.2 3 0 0 3 3 3 2 Tryptophan halogenase Abhydrolase_1 PF00561.20 CEH14929.1 - 0.016 14.8 0.6 0.18 11.5 0.0 2.5 2 1 1 3 3 3 0 alpha/beta hydrolase fold NAD_binding_8 PF13450.6 CEH14929.1 - 0.029 14.6 0.1 2.5 8.4 0.0 2.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CEH14929.1 - 0.03 13.6 0.0 2.3 7.4 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEH14929.1 - 0.034 13.4 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Thi4 family KAAG1 PF15354.6 CEH14930.1 - 0.3 11.7 5.3 16 6.1 0.6 3.6 1 1 1 2 2 2 0 Kidney-associated antigen 1 UPF0542 PF15086.6 CEH14930.1 - 0.47 10.4 1.3 1.6 8.7 0.1 2.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 Cpn60_TCP1 PF00118.24 CEH14932.1 - 3e-144 481.3 0.5 3.4e-144 481.1 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RTA1 PF04479.13 CEH14933.1 - 3.5e-44 150.9 6.3 3.5e-44 150.9 6.3 1.9 1 1 0 1 1 1 1 RTA1 like protein Fungal_trans PF04082.18 CEH14934.1 - 0.0026 16.9 0.2 0.0047 16.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 CEH14935.1 - 4.2e-08 32.1 0.0 1.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.21 CEH14935.1 - 0.00012 21.4 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 CEH14935.1 - 0.00024 20.4 0.0 0.34 10.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEH14935.1 - 0.0096 15.0 1.3 0.014 14.5 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 CEH14935.1 - 0.033 14.2 0.0 5.3 7.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CEH14935.1 - 0.036 13.3 0.0 2.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.29 CEH14936.1 - 4.3e-43 147.1 0.0 1.4e-42 145.4 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH14936.1 - 2.4e-31 108.4 0.0 4.6e-23 81.7 0.0 3.3 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CEH14936.1 - 8.7e-06 25.8 0.0 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rrp15p PF07890.12 CEH14936.1 - 0.21 12.0 7.7 0.74 10.1 7.7 2.0 1 0 0 1 1 1 0 Rrp15p Tom22 PF04281.13 CEH14936.1 - 0.24 11.2 1.6 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF2986 PF11661.8 CEH14936.1 - 0.76 10.4 4.8 0.14 12.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) ThrE PF06738.12 CEH14937.1 - 4.1e-57 193.3 6.8 4.1e-57 193.3 6.8 2.4 2 1 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 CEH14937.1 - 1.3e-10 41.6 2.6 1.3e-10 41.6 2.6 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Dak1 PF02733.17 CEH14941.1 - 1.9e-98 329.2 0.0 1.5e-97 326.2 0.0 2.0 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 CEH14941.1 - 9.9e-42 142.8 6.8 1.7e-41 142.0 6.8 1.4 1 0 0 1 1 1 1 DAK2 domain DNA_primase_lrg PF04104.14 CEH14943.1 - 3.5e-85 285.6 0.0 5.2e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Mis14 PF08641.12 CEH14944.1 - 2.5e-10 40.8 2.1 5e-10 39.8 2.1 1.5 1 0 0 1 1 1 1 Kinetochore protein Mis14 like DUF2570 PF10828.8 CEH14944.1 - 0.22 11.4 2.4 2.1 8.2 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Thioredoxin_4 PF13462.6 CEH14945.1 - 6.7e-10 39.4 0.0 9e-08 32.4 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin RPN1_RPN2_N PF17781.1 CEH14946.1 - 3.8e-121 404.2 0.0 1.9e-120 401.9 0.0 1.9 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 CEH14946.1 - 3.4e-18 65.1 14.3 0.00022 21.5 0.1 8.0 7 0 0 7 7 7 4 Proteasome/cyclosome repeat RPN1_C PF18051.1 CEH14946.1 - 5.9e-15 55.0 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 CEH14946.1 - 1.1e-05 25.7 0.4 0.48 10.9 0.0 3.7 3 0 0 3 3 3 2 HEAT repeats TPR_5 PF12688.7 CEH14946.1 - 0.16 12.2 1.2 3.4 7.9 0.1 3.2 3 0 0 3 3 3 0 Tetratrico peptide repeat Nop PF01798.18 CEH14947.1 - 1.3e-81 273.4 0.0 1.3e-81 273.4 0.0 2.2 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CEH14947.1 - 3.1e-16 59.5 0.1 1.3e-15 57.5 0.1 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DASH_Dad1 PF08649.10 CEH14948.1 - 6.8e-22 77.4 0.1 8.5e-22 77.1 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 SBDS_C PF09377.10 CEH14949.1 - 2e-34 118.1 0.0 4.6e-34 116.9 0.0 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 CEH14949.1 - 7.4e-32 109.3 0.5 1.3e-31 108.5 0.5 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HMMR_C PF15908.5 CEH14949.1 - 0.13 12.5 1.2 0.2 11.9 0.2 1.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal MCM PF00493.23 CEH14950.1 - 1.2e-99 331.9 0.0 1.7e-99 331.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEH14950.1 - 2.2e-38 131.0 0.0 3.8e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 CEH14950.1 - 3.2e-30 105.5 37.2 1.9e-29 102.9 28.9 3.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 CEH14950.1 - 1.7e-24 86.1 1.5 1.7e-24 86.1 1.5 2.5 3 0 0 3 3 2 1 MCM AAA-lid domain MCM_N PF14551.6 CEH14950.1 - 5.8e-13 49.3 0.0 1.6e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CEH14950.1 - 3.3e-08 33.2 0.0 1.2e-06 28.1 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CEH14950.1 - 9.4e-06 25.7 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CEH14950.1 - 0.00062 19.6 0.1 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SelR PF01641.18 CEH14950.1 - 0.018 15.1 0.1 1 9.5 0.1 2.4 2 0 0 2 2 2 0 SelR domain Zn_ribbon_2 PF12674.7 CEH14950.1 - 0.018 15.7 0.4 0.045 14.4 0.4 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain DUF1931 PF09123.11 CEH14950.1 - 0.026 14.7 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Sigma54_activat PF00158.26 CEH14950.1 - 0.034 13.9 0.1 0.24 11.1 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain SmaI PF17411.2 CEH14950.1 - 0.084 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease AAA PF00004.29 CEH14950.1 - 0.12 12.8 0.0 0.4 11.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CEH14950.1 - 0.15 11.9 3.3 0.18 11.7 0.2 2.7 2 0 0 2 2 2 0 AAA lid domain DSS1_SEM1 PF05160.13 CEH14951.1 - 2.2e-21 75.7 9.5 5.7e-21 74.3 9.5 1.6 1 1 0 1 1 1 1 DSS1/SEM1 family LSM PF01423.22 CEH14952.1 - 4.2e-13 48.8 0.1 5.3e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CEH14952.1 - 0.0009 18.8 0.1 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 Hfq protein Nkap_C PF06047.11 CEH14954.1 - 7e-45 151.3 4.5 7e-45 151.3 4.5 2.4 2 1 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain DUF3827 PF12877.7 CEH14954.1 - 4.5 5.5 19.5 7.5 4.8 19.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Macoilin PF09726.9 CEH14954.1 - 5.9 5.3 15.1 9.5 4.6 15.1 1.3 1 0 0 1 1 1 0 Macoilin family TPR_19 PF14559.6 CEH14955.1 - 5.7e-06 26.7 4.5 0.00011 22.6 6.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat F-box-like PF12937.7 CEH14955.1 - 6.8e-05 22.7 1.2 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEH14955.1 - 0.00071 19.4 0.1 0.00071 19.4 0.1 2.4 3 0 0 3 3 3 1 F-box domain TPR_14 PF13428.6 CEH14955.1 - 0.007 17.1 8.1 0.039 14.8 0.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CEH14955.1 - 0.018 15.0 1.0 0.043 13.7 1.0 1.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal TPR_2 PF07719.17 CEH14955.1 - 2.8 8.3 6.0 3.8 7.9 0.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 CEH14956.1 - 1.6e-12 47.1 0.0 3.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3678 PF12435.8 CEH14956.1 - 0.24 10.8 2.5 0.55 9.6 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Nuf2 PF03800.14 CEH14957.1 - 3.5e-34 117.9 0.1 1.1e-33 116.3 0.0 1.8 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 CEH14957.1 - 6.2e-12 45.6 23.1 6.2e-12 45.6 23.1 3.5 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain MerR-DNA-bind PF09278.11 CEH14957.1 - 0.34 11.5 9.3 0.2 12.2 1.2 3.5 2 1 0 2 2 2 0 MerR, DNA binding Urb2 PF10441.9 CEH14957.1 - 0.48 10.3 4.0 3.2 7.6 2.8 2.5 2 1 0 2 2 2 0 Urb2/Npa2 family NDUFB10 PF10249.9 CEH14957.1 - 0.97 9.9 6.1 0.097 13.2 1.0 2.0 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 Spc7 PF08317.11 CEH14957.1 - 9.6 5.0 33.9 0.012 14.6 12.2 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein Ribosomal_L29 PF00831.23 CEH14958.1 - 2.4e-17 62.7 1.4 2.4e-17 62.7 1.4 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein DUF5403 PF17395.2 CEH14958.1 - 0.12 12.6 0.5 0.24 11.7 0.2 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5403) HTH_12 PF08461.10 CEH14958.1 - 0.71 9.9 5.3 0.23 11.4 2.1 1.9 2 1 0 2 2 2 0 Ribonuclease R winged-helix domain Ribosomal_L18 PF17135.4 CEH14959.1 - 3.4e-90 300.5 1.9 3.8e-90 300.3 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CEH14959.1 - 0.0033 18.1 0.1 0.0033 18.1 0.1 2.1 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Adenylate_cycl PF01295.18 CEH14959.1 - 0.17 10.5 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I HMG_box_2 PF09011.10 CEH14961.1 - 0.24 12.0 1.4 1 10.0 0.0 2.6 3 0 0 3 3 3 0 HMG-box domain SCP1201-deam PF14428.6 CEH14961.1 - 2.7 7.9 4.4 8.3 6.3 0.1 3.0 2 1 1 3 3 3 0 SCP1.201-like deaminase WHEP-TRS PF00458.20 CEH14963.1 - 0.055 13.6 7.0 0.15 12.2 0.1 3.3 2 1 0 2 2 2 0 WHEP-TRS domain DUF4047 PF13256.6 CEH14963.1 - 0.093 12.9 0.7 0.24 11.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Ada_Zn_binding PF02805.16 CEH14963.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Metal binding domain of Ada Glyco_hydro2_C5 PF18565.1 CEH14963.1 - 0.21 11.5 2.9 13 5.7 0.1 2.6 3 0 0 3 3 3 0 Glycoside hydrolase family 2 C-terminal domain 5 Oxidored_molyb PF00174.19 CEH14964.1 - 6.7e-31 107.2 0.0 1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CEH14964.1 - 5.2e-08 33.0 0.0 1.7e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Calcipressin PF04847.12 CEH14965.1 - 7.1e-28 97.6 0.0 1.5e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 Calcipressin Voldacs PF03517.13 CEH14965.1 - 1.5e-16 60.8 1.5 7.4e-16 58.5 1.5 2.0 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Sugar_tr PF00083.24 CEH14966.1 - 2.7e-57 194.6 3.3 1.2e-54 185.9 0.8 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEH14966.1 - 1.5e-17 63.6 9.5 3.1e-17 62.5 9.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CEH14966.1 - 0.35 9.4 8.1 0.041 12.4 3.1 2.0 2 1 0 2 2 2 0 MFS/sugar transport protein Phage_holin_3_2 PF04550.12 CEH14966.1 - 2 9.0 7.8 0.33 11.5 1.9 2.6 2 0 0 2 2 2 0 Phage holin family 2 Chromate_transp PF02417.15 CEH14966.1 - 3.4 7.8 9.4 0.19 11.8 2.3 2.0 2 0 0 2 2 2 0 Chromate transporter Spt20 PF12090.8 CEH14968.1 - 0.41 10.2 2.4 0.66 9.5 2.4 1.3 1 0 0 1 1 1 0 Spt20 family Snf7 PF03357.21 CEH14969.1 - 4.2e-33 114.4 17.0 5e-33 114.1 17.0 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 CEH14969.1 - 0.043 13.7 4.8 0.052 13.5 4.8 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway TPR_MLP1_2 PF07926.12 CEH14969.1 - 0.15 12.1 10.5 0.49 10.5 10.1 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein YlqD PF11068.8 CEH14969.1 - 0.16 12.3 11.8 0.22 11.9 10.8 1.6 1 1 1 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.15 CEH14969.1 - 0.23 11.0 6.4 0.27 10.8 6.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Remorin_C PF03763.13 CEH14969.1 - 0.9 9.4 12.6 0.17 11.7 8.6 1.8 1 1 0 2 2 2 0 Remorin, C-terminal region OmpH PF03938.14 CEH14969.1 - 2.9 8.2 13.7 5.4 7.4 12.3 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Myb_DNA-bind_7 PF15963.5 CEH14970.1 - 4.9e-24 84.0 0.1 4.9e-24 84.0 0.1 2.1 2 0 0 2 2 2 1 Myb DNA-binding like HMG_box PF00505.19 CEH14970.1 - 1.7e-08 34.8 3.4 1.7e-08 34.8 3.4 3.0 2 0 0 2 2 2 1 HMG (high mobility group) box Myb_DNA-binding PF00249.31 CEH14970.1 - 5.6e-08 32.8 0.2 1.4e-07 31.5 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain HMG_box_2 PF09011.10 CEH14970.1 - 1.5e-05 25.5 5.2 1.5e-05 25.5 5.2 2.7 2 0 0 2 2 2 1 HMG-box domain Myb_DNA-bind_6 PF13921.6 CEH14970.1 - 0.097 12.9 0.3 0.24 11.7 0.3 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Nitroreductase PF00881.24 CEH14972.1 - 1.6e-26 93.3 0.1 6.5e-26 91.4 0.1 1.8 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 CEH14972.1 - 5.6e-08 32.6 0.0 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 2 Putative TM nitroreductase HbrB PF08539.11 CEH14973.1 - 1.3e-50 171.7 0.0 2.9e-50 170.6 0.0 1.6 1 0 0 1 1 1 1 HbrB-like His_Phos_1 PF00300.22 CEH14973.1 - 3.4e-34 118.2 0.5 2.2e-30 105.8 0.2 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Arf PF00025.21 CEH14974.1 - 2e-15 56.7 0.0 8.1e-13 48.2 0.0 2.6 1 1 0 2 2 2 2 ADP-ribosylation factor family AAA_16 PF13191.6 CEH14974.1 - 1.5e-09 38.5 0.0 2.9e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 CEH14974.1 - 1.6e-07 31.5 0.1 0.0011 19.2 0.0 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CEH14974.1 - 1.3e-06 27.8 0.2 0.00085 18.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CEH14974.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEH14974.1 - 0.008 15.6 0.0 0.024 14.0 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CEH14974.1 - 0.0085 15.7 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 1 Ras family TniB PF05621.11 CEH14974.1 - 0.025 14.0 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 CEH14974.1 - 0.047 14.0 0.1 0.079 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CEH14974.1 - 0.099 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEH14974.1 - 0.12 12.9 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter eRF1_2 PF03464.15 CEH14976.1 - 5e-44 149.8 0.0 8.3e-44 149.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CEH14976.1 - 2.7e-35 121.3 0.2 5.8e-35 120.2 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CEH14976.1 - 4.4e-18 65.5 0.0 7.5e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CEH14976.1 - 2.1e-09 37.8 0.0 3.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CEH14976.1 - 5e-09 36.5 0.0 1.3e-08 35.2 0.0 1.6 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 Ribosomal_L7Ae PF01248.26 CEH14977.1 - 4e-14 52.1 0.2 4.7e-14 51.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1512 PF07431.12 CEH14977.1 - 0.046 12.7 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DUF4605 PF15378.6 CEH14977.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) DUF4746 PF15928.5 CEH14978.1 - 0.11 11.9 6.6 0.25 10.7 6.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Rotamase PF00639.21 CEH14979.1 - 1e-17 64.8 0.0 1.4e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CEH14979.1 - 5.8e-16 59.1 0.0 9.2e-16 58.4 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CEH14979.1 - 1.2e-05 25.2 0.5 1.2e-05 25.2 0.5 1.8 2 0 0 2 2 2 1 WW domain Rhodanese PF00581.20 CEH14980.1 - 0.059 13.9 0.0 0.5 10.9 0.0 2.2 2 0 0 2 2 2 0 Rhodanese-like domain DUF2205 PF10224.9 CEH14981.1 - 3.5e-11 42.9 0.3 4.5e-11 42.6 0.3 1.2 1 0 0 1 1 1 1 Short coiled-coil protein MitMem_reg PF13012.6 CEH14981.1 - 0.17 12.3 1.3 1.6 9.2 0.2 1.9 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Ribosomal_S16 PF00886.19 CEH14986.1 - 5.3e-24 84.1 0.1 1.3e-23 82.8 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S16 CsbD PF05532.12 CEH14987.1 - 0.0019 18.0 5.2 0.0019 18.0 5.2 1.7 1 1 0 1 1 1 1 CsbD-like Vps51 PF08700.11 CEH14989.1 - 3.2e-17 62.4 0.3 6.5e-17 61.4 0.3 1.4 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 CEH14989.1 - 0.00018 21.7 0.7 0.00028 21.1 0.7 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 CEH14989.1 - 0.00018 20.3 1.0 0.00026 19.8 1.0 1.1 1 0 0 1 1 1 1 Dor1-like family LIF_OSM PF01291.17 CEH14989.1 - 0.051 13.7 0.2 0.077 13.1 0.2 1.2 1 0 0 1 1 1 0 LIF / OSM family SKA2 PF16740.5 CEH14989.1 - 0.057 13.2 0.3 0.2 11.5 0.1 1.9 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 FUSC PF04632.12 CEH14989.1 - 0.28 9.7 10.2 0.37 9.3 10.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FYVE PF01363.21 CEH14990.1 - 3.7e-17 62.2 3.4 6.6e-17 61.4 3.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 CEH14990.1 - 0.0033 17.1 0.4 0.0033 17.1 0.4 2.6 2 0 0 2 2 2 1 Rabenosyn Rab binding domain Zn-C2H2_12 PF18112.1 CEH14990.1 - 0.18 12.3 0.2 0.44 11.0 0.2 1.7 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain UPF0547 PF10571.9 CEH14990.1 - 0.24 11.5 1.9 0.61 10.2 1.9 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-piccolo PF05715.13 CEH14990.1 - 0.25 11.5 2.7 10 6.4 1.6 2.5 2 0 0 2 2 2 0 Piccolo Zn-finger DZR PF12773.7 CEH14990.1 - 2.2 8.4 4.7 6.4 6.9 2.4 2.2 2 0 0 2 2 2 0 Double zinc ribbon DEAD PF00270.29 CEH14991.1 - 1e-44 152.4 0.0 1.8e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH14991.1 - 7.4e-23 81.0 0.1 2.6e-22 79.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CEH14991.1 - 1.9e-20 72.9 0.1 4.3e-20 71.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CEH14991.1 - 4.5e-06 26.8 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 CEH14991.1 - 0.022 14.9 0.6 0.046 13.9 0.0 1.9 2 0 0 2 2 2 0 Helicase C-terminal domain CPSF73-100_C PF11718.8 CEH14992.1 - 1.2e-57 195.0 0.2 3.6e-57 193.4 0.0 1.8 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CEH14992.1 - 8.5e-30 103.3 0.0 1.9e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CEH14992.1 - 1.2e-19 70.5 0.0 2.6e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CEH14992.1 - 5e-18 65.8 0.1 1.1e-17 64.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 CEH14992.1 - 2.5e-17 62.6 0.3 4.7e-17 61.7 0.3 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CEH14992.1 - 1.1e-07 31.6 0.3 2.4e-06 27.2 0.2 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEH14992.1 - 2.4e-06 27.5 0.1 9.4e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain PMT PF02366.18 CEH14995.1 - 4.8e-77 258.9 16.7 4.8e-77 258.9 16.7 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CEH14995.1 - 1.6e-51 174.7 8.5 4.4e-51 173.3 8.5 1.8 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CEH14995.1 - 1.6e-23 83.5 0.1 3.1e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 MIR domain Pribosyltran PF00156.27 CEH14996.1 - 4.8e-06 26.2 0.0 1.3e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Trans_reg_C PF00486.28 CEH14996.1 - 0.036 14.1 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal EC042_2821 PF18740.1 CEH14996.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 EC042_2821-lke REase NAC PF01849.18 CEH14998.1 - 8.3e-19 67.3 0.0 2e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 NAC domain Wzz PF02706.15 CEH14998.1 - 0.14 12.4 0.9 0.31 11.4 0.9 1.5 1 0 0 1 1 1 0 Chain length determinant protein PGA2 PF07543.12 CEH14998.1 - 4 7.4 7.7 7 6.6 7.7 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Ribosomal_L2_C PF03947.18 CEH14999.1 - 2e-29 102.3 0.2 8.9e-29 100.3 0.2 2.1 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CEH14999.1 - 2e-25 88.6 0.4 4.6e-25 87.4 0.4 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Striatin PF08232.12 CEH15000.1 - 1.9e-50 171.5 0.0 1.9e-50 171.5 0.0 2.4 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 CEH15000.1 - 7e-36 121.6 5.3 8.3e-06 26.5 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH15000.1 - 0.00036 20.8 0.0 19 5.6 0.0 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Choline_transpo PF04515.12 CEH15001.1 - 3.7e-53 180.8 0.8 9.7e-53 179.5 0.1 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter AA_kinase PF00696.28 CEH15001.1 - 1.8e-36 126.0 0.0 5.4e-36 124.4 0.0 1.9 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 CEH15001.1 - 1.2e-09 37.8 0.4 0.00084 19.1 0.0 2.9 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 CEH15001.1 - 1.5e-09 37.5 1.1 2.9e-06 27.0 0.2 2.7 2 0 0 2 2 2 2 ACT domain Dus PF01207.17 CEH15002.1 - 9.6e-44 149.7 0.0 5.8e-31 107.7 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Torus PF16131.5 CEH15002.1 - 1.2 9.8 5.2 0.68 10.7 1.7 2.3 2 0 0 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 CEH15002.1 - 1.6 8.6 7.0 2.5 8.0 0.9 3.2 3 0 0 3 3 3 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEH15002.1 - 3.8 7.7 6.6 4 7.6 0.2 3.1 2 1 1 3 3 3 0 Zinc finger domain Atg8 PF02991.16 CEH15003.1 - 9.5e-52 173.5 0.1 1.1e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CEH15003.1 - 5.4e-07 29.9 0.0 6.6e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Alg6_Alg8 PF03155.15 CEH15005.1 - 3.8e-140 468.1 18.0 1.1e-135 453.4 15.0 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Rad51 PF08423.11 CEH15006.1 - 4.1e-12 45.9 0.3 1.2e-10 41.1 0.1 2.2 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.6 CEH15006.1 - 0.00066 19.3 0.1 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CEH15006.1 - 0.0028 17.2 0.2 0.0043 16.5 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CEH15006.1 - 0.067 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 KaiC Ligase_CoA PF00549.19 CEH15008.1 - 4.2e-09 36.4 0.0 1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase SpoIIE PF07228.12 CEH15008.1 - 1e-06 28.8 0.0 0.002 18.1 0.0 2.9 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) AF-4 PF05110.13 CEH15008.1 - 4.2 5.3 17.9 8 4.4 17.9 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SNARE_assoc PF09335.11 CEH15009.1 - 2.4e-12 47.4 3.4 2.4e-12 47.4 3.4 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DSPc PF00782.20 CEH15011.1 - 7.7e-19 67.8 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RhoGAP PF00620.27 CEH15012.1 - 3.9e-37 127.4 0.0 6.9e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 CEH15012.1 - 1.4e-12 48.1 0.0 3.8e-11 43.5 0.0 2.7 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CEH15012.1 - 6.5e-11 42.4 0.0 1.9e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 RasGEF N-terminal motif PH PF00169.29 CEH15012.1 - 1.1e-05 25.8 0.1 0.029 14.9 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 CEH15012.1 - 0.036 14.4 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Gly-zipper_Omp PF13488.6 CEH15012.1 - 5.1 7.2 13.7 19 5.3 13.7 2.0 1 0 0 1 1 1 0 Glycine zipper Gpr1_Fun34_YaaH PF01184.19 CEH15013.1 - 3.9e-25 88.7 20.7 4.6e-25 88.4 20.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family TMEM223 PF14640.6 CEH15013.1 - 0.1 12.8 0.8 15 5.7 0.3 2.4 2 0 0 2 2 2 0 Transmembrane protein 223 OsmC PF02566.19 CEH15014.1 - 1.5e-16 60.7 0.0 2.2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein PYNP_C PF07831.13 CEH15014.1 - 0.091 12.4 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain R3H PF01424.22 CEH15015.1 - 1.2e-11 44.5 0.2 2.1e-11 43.6 0.2 1.4 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 CEH15015.1 - 1.4e-07 31.2 0.1 3.6e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OPT PF03169.15 CEH15016.1 - 8e-166 553.2 52.3 9.4e-166 553.0 52.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 CEH15016.1 - 0.84 9.9 6.6 3.5 7.9 6.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) DUF3275 PF11679.8 CEH15017.1 - 1.8 8.5 5.2 0.35 10.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) IDO PF01231.18 CEH15018.1 - 7.8e-136 453.3 0.0 9.5e-136 453.0 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PBP PF01161.20 CEH15019.1 - 8.4e-06 26.1 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Not1 PF04054.15 CEH15020.1 - 1.6e-107 359.7 0.0 4.3e-107 358.2 0.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CEH15020.1 - 1.2e-92 309.4 4.2 2e-92 308.6 2.0 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 CEH15020.1 - 2.2e-53 180.2 0.9 2.2e-53 180.2 0.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 CEH15020.1 - 3.7e-48 163.2 0.0 3.7e-48 163.2 0.0 2.8 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 CEH15020.1 - 2e-47 161.1 1.0 2e-47 161.1 1.0 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF2992 PF11208.8 CEH15020.1 - 1.8 8.8 17.5 0.018 15.3 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Tht1 PF04163.12 CEH15021.1 - 9.1e-09 34.6 0.2 1.7e-08 33.7 0.2 1.4 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein FRG PF08867.11 CEH15021.1 - 0.064 14.2 2.8 0.069 14.1 0.7 2.1 2 0 0 2 2 2 0 FRG domain PAGK PF15284.6 CEH15021.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.5 3 0 0 3 3 3 0 Phage-encoded virulence factor CENP-Q PF13094.6 CEH15021.1 - 2.3 8.4 17.1 14 5.8 17.1 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit AA_permease_2 PF13520.6 CEH15022.1 - 2.2e-49 168.5 49.7 2.7e-49 168.1 49.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEH15022.1 - 1.9e-26 92.8 45.3 2.5e-26 92.3 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2620 PF10941.8 CEH15022.1 - 0.13 12.4 0.1 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF2620 EcsC PF12787.7 CEH15022.1 - 1.6 8.3 2.9 2.8 7.5 2.9 1.3 1 0 0 1 1 1 0 EcsC protein family Sec7 PF01369.20 CEH15023.1 - 1.2e-65 220.6 0.0 1.9e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CEH15023.1 - 1.1e-14 54.6 0.1 1.1e-12 48.1 0.0 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal CAP_N PF01213.19 CEH15023.1 - 4.5 6.7 5.8 9.2 5.6 5.8 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PDEase_II PF02112.15 CEH15024.1 - 8.5e-36 123.7 0.0 1.9e-35 122.6 0.0 1.5 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 CEH15024.1 - 0.063 12.8 0.1 0.16 11.5 0.1 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Peptidase_M13_N PF05649.13 CEH15025.1 - 6.6e-87 292.7 0.0 8.6e-87 292.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CEH15025.1 - 1.3e-55 188.2 0.0 2.2e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 DUF4094 PF13334.6 CEH15025.1 - 0.17 12.4 0.0 8.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Mcl1_mid PF12341.8 CEH15026.1 - 1.6e-73 247.7 0.0 3.1e-73 246.7 0.0 1.5 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 CEH15026.1 - 1.2e-08 35.4 0.9 0.19 12.7 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH15026.1 - 3.7e-06 27.2 0.0 0.00012 22.3 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain ALG3 PF05208.13 CEH15027.1 - 2e-118 396.0 6.1 2.4e-118 395.7 6.1 1.0 1 0 0 1 1 1 1 ALG3 protein Hid1 PF12722.7 CEH15028.1 - 1.7e-119 400.2 0.0 1.8e-104 350.5 0.0 3.2 2 1 1 3 3 3 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CEH15028.1 - 1.9e-59 201.7 0.0 4.3e-59 200.5 0.0 1.5 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DNA_pol_phi PF04931.13 CEH15028.1 - 0.3 9.2 16.5 0.49 8.4 16.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 CEH15028.1 - 1.8 7.5 7.0 17 4.2 0.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) SGL PF08450.12 CEH15029.1 - 0.00048 19.8 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region TrkH PF02386.16 CEH15031.1 - 1.4e-109 366.8 12.6 6.6e-107 358.0 3.9 2.1 2 0 0 2 2 2 2 Cation transport protein zf-RING_2 PF13639.6 CEH15032.1 - 0.00017 21.8 5.4 0.0038 17.5 2.7 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CEH15032.1 - 0.013 15.4 1.6 0.013 15.4 1.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEH15032.1 - 0.018 14.9 3.9 0.018 14.9 3.9 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEH15032.1 - 0.28 11.1 7.9 0.62 10.0 4.4 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEH15032.1 - 0.79 10.0 4.5 0.44 10.9 1.8 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain COesterase PF00135.28 CEH15033.1 - 3.5e-89 300.0 0.0 4.3e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CEH15033.1 - 2.9e-05 24.0 1.0 0.00012 22.0 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Serglycin PF04360.12 CEH15033.1 - 0.075 13.0 0.5 0.14 12.1 0.5 1.3 1 0 0 1 1 1 0 Serglycin RNA_pol_Rpb1_5 PF04998.17 CEH15036.1 - 1.7e-82 276.8 0.5 2.9e-82 276.1 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CEH15036.1 - 1.3e-79 267.8 0.0 2.4e-79 266.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CEH15036.1 - 8.2e-70 234.3 0.0 1.4e-69 233.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CEH15036.1 - 1.2e-36 126.0 0.0 3.2e-36 124.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CEH15036.1 - 4.4e-30 103.8 0.0 1.1e-29 102.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-ISL3 PF14690.6 CEH15036.1 - 0.022 15.4 0.3 0.022 15.4 0.3 2.4 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF4349 PF14257.6 CEH15037.1 - 0.24 10.8 2.7 0.38 10.2 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) WD40 PF00400.32 CEH15038.1 - 2.4e-15 56.7 18.9 0.0068 17.2 0.3 6.3 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH15038.1 - 5.6e-08 33.0 0.3 0.17 12.2 0.0 5.8 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEH15038.1 - 0.015 14.3 0.5 0.1 11.6 0.2 2.4 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Endonuclease_NS PF01223.23 CEH15039.1 - 8.9e-53 179.4 0.0 1.4e-50 172.2 0.0 2.1 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease UPF0121 PF03661.13 CEH15041.1 - 2.9e-47 161.1 3.9 3.4e-47 160.9 3.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) IPPT PF01715.17 CEH15042.1 - 1.7e-56 191.6 0.8 1.5e-30 106.7 0.3 2.3 2 0 0 2 2 2 2 IPP transferase UPF0020 PF01170.18 CEH15042.1 - 2.4e-06 27.4 0.1 1.4e-05 24.9 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AAA_33 PF13671.6 CEH15042.1 - 0.00011 22.3 0.2 0.28 11.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 CEH15042.1 - 0.011 15.2 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 CEH15042.1 - 0.012 16.1 0.0 0.028 14.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 CEH15042.1 - 0.014 16.0 0.3 0.64 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CEH15042.1 - 0.024 14.2 0.1 0.079 12.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEH15042.1 - 0.037 14.3 0.2 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CEH15042.1 - 0.048 13.8 0.1 0.16 12.1 0.1 1.9 1 0 0 1 1 1 0 Helicase HerA, central domain IPT PF01745.16 CEH15042.1 - 0.072 12.5 1.8 0.18 11.2 0.1 2.5 2 1 0 2 2 2 0 Isopentenyl transferase RsgA_GTPase PF03193.16 CEH15042.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase dsrm PF00035.26 CEH15043.1 - 4.2e-05 24.2 0.0 7.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 CEH15043.1 - 0.047 14.3 0.4 0.1 13.2 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease III domain SPT16 PF08644.11 CEH15044.1 - 8.5e-57 191.6 0.1 2e-56 190.4 0.1 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 CEH15044.1 - 3e-43 147.4 0.4 9.6e-43 145.8 0.4 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 CEH15044.1 - 2.9e-24 85.9 0.0 5.5e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CEH15044.1 - 1.8e-13 50.7 0.1 6e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF1373 PF07117.11 CEH15044.1 - 6.5 6.7 9.8 16 5.4 9.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) BTB PF00651.31 CEH15045.1 - 2.8e-10 40.4 0.0 0.00013 22.1 0.0 3.3 3 0 0 3 3 3 3 BTB/POZ domain MATH PF00917.26 CEH15045.1 - 0.046 13.9 0.2 0.099 12.8 0.2 1.6 1 0 0 1 1 1 0 MATH domain FAD_binding_8 PF08022.12 CEH15046.1 - 1.2e-18 67.2 0.0 3e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CEH15046.1 - 1.8e-12 47.5 8.3 4.9e-12 46.1 8.3 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEH15046.1 - 5.8e-12 46.0 0.0 1.8e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain EF-hand_7 PF13499.6 CEH15046.1 - 8.2e-06 26.2 0.5 2e-05 25.0 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CEH15046.1 - 9.6e-05 22.0 0.3 0.00034 20.3 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CEH15046.1 - 0.00036 19.9 0.2 0.001 18.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CEH15046.1 - 0.0024 17.3 0.1 0.007 15.8 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CEH15046.1 - 0.004 17.0 0.1 0.013 15.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair Hep_59 PF07052.11 CEH15047.1 - 5.8e-25 88.1 0.4 5.8e-25 88.1 0.4 2.7 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 AMP-binding PF00501.28 CEH15048.1 - 2e-73 247.4 0.0 2.8e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEH15048.1 - 1.1e-14 55.1 2.9 3e-14 53.8 0.4 3.0 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 CEH15050.1 - 2.9e-73 246.5 0.0 3.5e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15050.1 - 2.3e-30 105.8 0.0 2.9e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH15050.1 - 9.6e-09 35.0 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEH15050.1 - 3.9e-05 22.6 0.0 6.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEH15050.1 - 0.00072 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH15050.1 - 0.0067 16.4 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family NTF2 PF02136.20 CEH15052.1 - 2.9e-07 31.1 0.0 2.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 CEH15052.1 - 1.8e-06 28.0 0.0 1.5e-05 25.0 0.0 2.0 1 1 1 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 AMP-binding PF00501.28 CEH15053.1 - 5.1e-75 252.7 0.0 6.7e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ThrE PF06738.12 CEH15056.1 - 3.9e-50 170.5 23.1 1e-49 169.1 4.6 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CEH15056.1 - 3.6e-09 36.8 9.9 3.6e-09 36.8 9.9 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Mit_ribos_Mrp51 PF11709.8 CEH15057.1 - 3.9e-13 49.7 0.1 1.8e-12 47.5 0.1 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit QCR10 PF09796.9 CEH15058.1 - 4.3e-25 87.5 0.1 5.7e-25 87.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.10 CEH15058.1 - 0.05 13.5 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein HOOK PF05622.12 CEH15059.1 - 9.8e-58 195.9 47.2 9.8e-58 195.9 47.2 2.1 1 1 1 2 2 2 2 HOOK protein NYD-SP28_assoc PF14775.6 CEH15059.1 - 0.88 9.7 4.3 1.4 9.1 0.6 3.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain Adaptin_N PF01602.20 CEH15060.1 - 3.8e-139 464.6 1.3 4.9e-139 464.3 1.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CEH15060.1 - 6.7e-57 192.0 0.2 1.8e-53 180.9 0.0 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEH15060.1 - 2.5e-14 53.4 7.0 4.7e-07 30.1 0.2 6.0 2 1 4 6 6 6 3 HEAT repeats HEAT PF02985.22 CEH15060.1 - 4.9e-11 41.9 4.4 0.0078 16.4 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat Cnd3 PF12719.7 CEH15060.1 - 5.4e-06 25.8 0.2 0.0053 16.0 0.1 2.4 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 CEH15060.1 - 2.7e-05 24.6 1.9 0.23 12.0 0.1 6.0 5 2 2 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 CEH15060.1 - 5.2e-05 22.9 0.1 0.11 12.0 0.0 3.0 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.23 CEH15060.1 - 0.0013 18.7 1.1 0.61 10.2 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 CEH15060.1 - 0.019 15.2 2.4 2.8 8.1 0.0 4.2 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 CEH15060.1 - 0.17 11.8 1.1 0.97 9.3 0.1 2.5 2 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Ras PF00071.22 CEH15061.1 - 8.4e-63 210.8 0.9 9.8e-63 210.6 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH15061.1 - 6e-35 120.1 0.1 9.3e-35 119.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH15061.1 - 2.3e-17 63.0 0.1 2.9e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEH15061.1 - 4.2e-06 26.5 0.5 1.5e-05 24.6 0.5 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEH15061.1 - 7.6e-06 25.9 0.8 0.0098 15.8 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase SRPRB PF09439.10 CEH15061.1 - 7.7e-06 25.5 0.0 1.2e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEH15061.1 - 1.8e-05 24.2 0.1 2.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEH15061.1 - 0.00095 19.2 0.1 0.0015 18.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH15061.1 - 0.0074 15.8 0.1 0.054 13.0 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_5 PF07728.14 CEH15061.1 - 0.0089 16.0 0.0 0.02 14.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CEH15061.1 - 0.01 16.2 0.1 0.57 10.6 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CEH15061.1 - 0.012 15.1 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 CEH15061.1 - 0.024 15.0 0.0 0.03 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CEH15061.1 - 0.031 14.8 0.0 0.046 14.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CEH15061.1 - 0.034 14.4 0.1 0.074 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CEH15061.1 - 0.042 13.6 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 CEH15061.1 - 0.051 13.0 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Na_H_Exchanger PF00999.21 CEH15062.1 - 1.3e-64 218.4 37.7 1.6e-64 218.1 37.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Dabb PF07876.12 CEH15064.1 - 1e-14 54.9 0.0 1.1e-14 54.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ran_BP1 PF00638.18 CEH15065.1 - 2.2e-11 44.1 0.1 5.2e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 RanBP1 domain PAPS_reduct PF01507.19 CEH15066.1 - 3.8e-21 75.9 0.0 1.2e-16 61.2 0.0 2.6 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Pkinase PF00069.25 CEH15067.1 - 9.4e-72 241.5 0.0 1.5e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Abhydrolase_3 PF07859.13 CEH15067.1 - 1.9e-44 152.0 0.0 4.6e-44 150.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pkinase_Tyr PF07714.17 CEH15067.1 - 2.1e-33 115.7 0.0 3.6e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Say1_Mug180 PF10340.9 CEH15067.1 - 1.2e-10 40.9 0.0 3.5e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase YrbL-PhoP_reg PF10707.9 CEH15067.1 - 0.00058 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 CEH15067.1 - 0.0012 18.2 0.0 0.0034 16.8 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEH15067.1 - 0.1 11.3 0.0 0.1 11.3 0.0 2.3 2 1 0 2 2 2 0 Fungal protein kinase SOR_SNZ PF01680.17 CEH15069.1 - 5e-112 372.7 5.0 6.8e-112 372.2 5.0 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 CEH15069.1 - 2.3e-07 30.4 5.2 3.5e-05 23.3 0.2 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 CEH15069.1 - 0.0059 15.7 0.2 2.7 7.0 0.1 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 CEH15069.1 - 0.013 14.7 0.4 0.18 10.9 0.0 2.6 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 CEH15069.1 - 0.036 13.2 0.1 0.59 9.2 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 CEH15069.1 - 0.038 13.5 0.3 0.7 9.3 0.0 2.4 3 0 0 3 3 3 0 Histidine biosynthesis protein TetR_C_27 PF17935.1 CEH15069.1 - 0.089 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PGAP1 PF07819.13 CEH15070.1 - 0.017 14.9 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 CEH15070.1 - 0.022 14.0 0.3 0.039 13.2 0.3 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 CEH15070.1 - 0.027 14.3 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 CEH15070.1 - 0.028 13.9 0.0 0.067 12.7 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 CEH15070.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 CEH15070.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CEH15070.1 - 0.13 12.9 10.7 0.13 12.9 9.5 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family UCR_TM PF02921.14 CEH15071.1 - 2.9e-12 46.9 0.7 2.9e-12 46.9 0.7 2.0 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 CEH15071.1 - 1.5e-10 40.9 0.0 2.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF1772 PF08592.11 CEH15072.1 - 4.5e-12 46.5 1.2 4.5e-12 46.5 1.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF423 PF04241.15 CEH15074.1 - 1.3e-24 86.2 4.2 1.8e-24 85.7 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Ion_trans PF00520.31 CEH15075.1 - 4e-126 419.2 65.9 3.3e-41 141.1 3.3 5.1 5 0 0 5 5 5 5 Ion transport protein PKD_channel PF08016.12 CEH15075.1 - 0.0017 17.2 58.5 0.04 12.6 2.0 8.0 7 2 1 8 8 8 7 Polycystin cation channel Arf PF00025.21 CEH15076.1 - 6.7e-76 253.6 0.0 7.7e-76 253.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEH15076.1 - 2.8e-15 56.6 0.0 3.8e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEH15076.1 - 8.3e-13 48.3 0.0 9e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CEH15076.1 - 2.1e-11 43.6 0.5 7.2e-07 28.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CEH15076.1 - 3.6e-11 42.8 0.0 4.5e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEH15076.1 - 1.9e-09 37.3 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEH15076.1 - 0.00025 21.1 0.0 0.00037 20.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CEH15076.1 - 0.0016 17.8 0.1 0.0025 17.2 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase DUF4185 PF13810.6 CEH15076.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Glyco_hydro_5_C PF18564.1 CEH15077.1 - 7.1e-19 68.1 0.0 1.5e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 CEH15077.1 - 2.1e-12 47.1 0.0 4.8e-05 22.9 0.0 3.0 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) GMC_oxred_C PF05199.13 CEH15077.1 - 0.0042 17.6 0.0 0.0095 16.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase zf-C3HC4_3 PF13920.6 CEH15078.1 - 2.8e-06 27.1 9.0 2.8e-06 27.1 9.0 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 CEH15078.1 - 0.094 13.2 0.2 0.094 13.2 0.2 5.3 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C3HC4 PF00097.25 CEH15078.1 - 9.6 6.2 28.9 0.35 10.8 11.1 3.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CEH15079.1 - 5.6e-44 150.0 0.2 9.7e-44 149.2 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH15079.1 - 8.7e-32 109.8 0.1 3.9e-31 107.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH15079.1 - 4.7e-06 26.7 0.0 7.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CEH15079.1 - 0.001 19.5 0.5 0.0068 16.7 0.3 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEH15079.1 - 0.0019 17.9 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 CEH15079.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 CEH15079.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Helicase Dynactin PF12455.8 CEH15081.1 - 3.5e-75 252.9 0.6 3.5e-75 252.9 0.6 4.2 4 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 CEH15081.1 - 6.1e-20 71.0 0.1 9.9e-20 70.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Gal11_ABD1 PF18535.1 CEH15081.1 - 0.02 15.0 0.3 0.074 13.1 0.0 2.1 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) SesA PF17107.5 CEH15081.1 - 5.7 7.2 14.9 0.54 10.5 2.3 3.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Far-17a_AIG1 PF04750.14 CEH15082.1 - 0.016 14.5 13.3 0.0077 15.6 9.0 2.2 1 1 1 2 2 2 0 FAR-17a/AIG1-like protein MFS_1 PF07690.16 CEH15083.1 - 6.4e-29 101.0 23.1 6.4e-29 101.0 23.1 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_17 PF17668.1 CEH15083.1 - 0.054 14.3 0.6 0.63 10.9 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SE PF08491.10 CEH15084.1 - 5.2e-95 317.6 0.0 8.5e-95 316.9 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CEH15084.1 - 1.2e-11 44.4 0.0 2.3e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 CEH15084.1 - 2.3e-09 37.3 0.6 2.1e-05 24.3 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CEH15084.1 - 0.00029 20.3 1.5 0.00048 19.6 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEH15084.1 - 0.00067 19.8 2.2 0.0027 17.9 0.9 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CEH15084.1 - 0.0011 17.9 0.8 0.38 9.6 0.2 2.2 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 CEH15084.1 - 0.0015 17.7 0.3 0.03 13.4 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CEH15084.1 - 0.0038 16.5 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEH15084.1 - 0.014 14.7 0.1 0.042 13.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 CEH15084.1 - 0.016 13.9 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 CEH15084.1 - 0.063 13.9 0.5 0.15 12.7 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEH15084.1 - 0.13 11.3 2.7 0.13 11.3 1.5 1.5 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 CEH15084.1 - 0.16 11.3 0.2 0.29 10.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain BatA PF07584.11 CEH15084.1 - 2.9 8.3 7.5 85 3.6 0.3 3.7 3 1 0 3 3 3 0 Aerotolerance regulator N-terminal Cyclase PF04199.13 CEH15085.1 - 1.1e-17 64.5 0.0 1.8e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase RabGAP-TBC PF00566.18 CEH15086.1 - 2.2e-33 115.7 0.0 3.7e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 CEH15087.1 - 8.6e-69 231.8 0.0 1.2e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15087.1 - 3.3e-49 167.5 0.0 4.8e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH15087.1 - 8e-06 24.9 0.1 2e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CEH15087.1 - 0.00077 18.9 0.0 0.0028 17.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like UBA PF00627.31 CEH15088.1 - 0.00064 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Pil1 PF13805.6 CEH15089.1 - 1.9e-32 112.9 4.0 2.8e-32 112.3 4.0 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 DUF4201 PF13870.6 CEH15089.1 - 0.096 12.4 4.5 0.18 11.5 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Cnn_1N PF07989.11 CEH15089.1 - 0.11 12.7 4.9 0.22 11.7 4.9 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 GIT_CC PF16559.5 CEH15089.1 - 0.12 12.3 0.9 0.31 10.9 0.9 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Gp-FAR-1 PF05823.12 CEH15089.1 - 0.12 12.7 0.6 0.23 11.8 0.6 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) APG6_N PF17675.1 CEH15089.1 - 0.16 12.5 3.1 0.36 11.4 3.1 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Prefoldin_2 PF01920.20 CEH15089.1 - 0.2 11.7 2.4 0.28 11.2 1.4 1.7 1 1 0 1 1 1 0 Prefoldin subunit PspB PF06667.12 CEH15089.1 - 0.2 11.7 0.1 0.52 10.4 0.1 1.7 1 0 0 1 1 1 0 Phage shock protein B DUF2730 PF10805.8 CEH15089.1 - 0.24 11.5 0.8 0.5 10.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) UPF0242 PF06785.11 CEH15089.1 - 0.36 10.9 2.7 0.6 10.2 2.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 CEH15089.1 - 0.39 9.6 5.5 0.32 9.8 3.8 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 CEH15089.1 - 0.68 9.0 3.9 1.1 8.3 3.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 CEH15089.1 - 3.7 8.0 5.9 4.7 7.7 4.7 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 CEH15089.1 - 4.1 7.5 7.9 12 6.0 7.9 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding MBG PF17883.1 CEH15091.1 - 0.045 14.3 0.1 10 6.8 0.3 2.3 2 0 0 2 2 2 0 MBG domain Profilin PF00235.19 CEH15091.1 - 0.047 14.0 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Profilin DUF4887 PF16228.5 CEH15093.1 - 2.9 8.0 20.2 0.8 9.9 14.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) SNARE_assoc PF09335.11 CEH15094.1 - 1.4e-12 48.1 3.8 1.4e-12 48.1 3.8 2.7 2 1 2 4 4 4 1 SNARE associated Golgi protein COX7a PF02238.15 CEH15094.1 - 0.018 15.4 0.2 0.065 13.6 0.2 2.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII Myb_DNA-bind_6 PF13921.6 CEH15098.1 - 0.003 17.8 0.0 0.005 17.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CEH15098.1 - 0.07 13.3 0.0 4.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Corona_nucleoca PF00937.18 CEH15098.1 - 0.096 11.7 1.3 0.095 11.7 1.3 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein HTH_AsnC-type PF13404.6 CEH15098.1 - 0.39 10.6 2.3 1.7 8.6 2.3 1.9 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain YdaS_antitoxin PF15943.5 CEH15099.1 - 0.012 15.4 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Colicin-DNase PF12639.7 CEH15099.1 - 0.063 14.1 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin Myb_DNA-binding PF00249.31 CEH15100.1 - 0.00028 21.0 0.3 0.5 10.6 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH15100.1 - 0.00096 19.4 0.2 0.0021 18.3 0.2 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.8 CEH15100.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TetR_C_8 PF14278.6 CEH15100.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region YdaS_antitoxin PF15943.5 CEH15101.1 - 0.12 12.2 0.8 0.47 10.4 0.2 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Myb_DNA-binding PF00249.31 CEH15102.1 - 0.00065 19.8 0.0 0.0037 17.4 0.0 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain ORF45 PF17620.2 CEH15103.1 - 0.17 12.0 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function CybS PF05328.12 CEH15104.1 - 4.9e-40 136.3 0.0 6e-40 136.0 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Mito_carr PF00153.27 CEH15105.1 - 0.018 14.9 0.5 0.21 11.5 0.1 2.6 2 1 0 2 2 2 0 Mitochondrial carrier protein Rod_cone_degen PF15201.6 CEH15105.1 - 0.18 11.9 4.3 12 6.1 0.1 3.6 3 0 0 3 3 3 0 Progressive rod-cone degeneration DUF938 PF06080.12 CEH15106.1 - 1.2e-32 113.3 1.5 9.1e-16 58.2 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF938) TAXi_C PF14541.6 CEH15106.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal COX4 PF02936.14 CEH15107.1 - 1.8e-38 131.7 0.1 2.5e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV SPAM PF02090.15 CEH15107.1 - 0.024 14.4 0.0 0.024 14.4 0.0 1.4 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein HMG_box_2 PF09011.10 CEH15107.1 - 0.12 13.0 6.2 0.4 11.3 0.1 2.9 2 1 1 3 3 3 0 HMG-box domain Pyr_redox_2 PF07992.14 CEH15108.1 - 2.1e-51 174.9 0.4 2.4e-51 174.7 0.4 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEH15108.1 - 1.5e-18 67.1 0.6 6.9e-15 55.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEH15108.1 - 6.3e-17 61.9 0.5 6.5e-14 52.3 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEH15108.1 - 7.1e-06 26.2 0.1 0.0011 19.1 0.0 2.7 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CEH15108.1 - 3.2e-05 23.2 3.5 0.0062 15.7 0.1 3.4 3 1 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 CEH15108.1 - 3.7e-05 23.3 0.0 0.0057 16.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 CEH15108.1 - 3.7e-05 23.1 0.4 0.00022 20.6 0.0 2.2 2 1 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 CEH15108.1 - 0.00025 20.3 2.4 0.01 14.9 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 CEH15108.1 - 0.00042 20.7 0.1 0.074 13.5 0.0 2.9 2 2 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CEH15108.1 - 0.00085 18.7 0.5 0.026 13.8 0.0 2.7 2 1 1 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 CEH15108.1 - 0.0011 18.2 0.2 0.68 9.0 0.0 3.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CEH15108.1 - 0.0013 18.3 0.5 0.19 11.3 0.3 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CEH15108.1 - 0.0018 17.2 0.2 0.054 12.3 0.0 2.6 2 1 1 3 3 3 1 Tryptophan halogenase Shikimate_DH PF01488.20 CEH15108.1 - 0.0041 17.2 0.1 3.9 7.5 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 CEH15108.1 - 0.005 15.6 0.1 0.029 13.1 0.1 2.2 3 0 0 3 3 3 1 HI0933-like protein F420_oxidored PF03807.17 CEH15108.1 - 0.016 15.8 0.1 0.99 10.0 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SH3BGR PF04908.15 CEH15109.1 - 2.7e-07 30.6 0.0 1.3e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein PCI PF01399.27 CEH15110.1 - 1.9e-09 38.0 0.6 7.9e-09 36.0 0.1 2.4 2 0 0 2 2 2 1 PCI domain DUF5497 PF17601.2 CEH15110.1 - 0.011 16.1 0.1 0.27 11.6 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5497) Aminotran_5 PF00266.19 CEH15111.1 - 1.8e-31 109.5 0.0 1.1e-21 77.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V HAD_2 PF13419.6 CEH15112.1 - 1.2e-08 35.3 0.0 2.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEH15112.1 - 2.6e-05 24.6 0.0 7.6e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEH15112.1 - 0.00026 21.0 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.8 CEH15112.1 - 0.046 13.2 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) HTH_1 PF00126.27 CEH15112.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.5 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family SUZ PF12752.7 CEH15113.1 - 4.5e-10 40.1 4.5 4.5e-10 40.1 4.5 6.6 6 1 0 6 6 6 1 SUZ domain UCH PF00443.29 CEH15114.1 - 1.3e-41 142.9 0.0 1.7e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEH15114.1 - 4.1e-09 36.5 0.0 9.4e-07 28.7 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase An_peroxidase PF03098.15 CEH15115.1 - 6.2e-37 127.4 0.1 8e-28 97.3 0.1 3.4 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 CEH15115.1 - 6.1e-11 41.7 0.0 1.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 CEH15117.1 - 2.6e-75 253.9 33.1 3.4e-75 253.5 33.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEH15117.1 - 4.2e-15 55.3 31.6 8.2e-15 54.3 31.5 1.5 1 1 0 1 1 1 1 Amino acid permease Herpes_U26 PF07402.11 CEH15117.1 - 0.044 13.4 2.1 0.22 11.1 0.1 2.2 2 0 0 2 2 2 0 Human herpesvirus U26 protein AgrB PF04647.15 CEH15117.1 - 2.3 7.5 6.1 1.9 7.8 0.2 3.0 3 1 0 3 3 3 0 Accessory gene regulator B SOCS PF12610.8 CEH15118.1 - 0.56 10.6 5.5 3.5 8.1 0.2 2.4 2 0 0 2 2 2 0 Suppressor of cytokine signalling HEAT_2 PF13646.6 CEH15119.1 - 1.2e-05 25.5 11.2 0.021 15.2 0.0 5.1 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 CEH15119.1 - 6e-05 23.0 22.6 0.081 13.2 0.0 8.2 10 0 0 10 10 10 3 HEAT repeat Cnd1 PF12717.7 CEH15119.1 - 0.0036 17.4 0.4 2.5 8.1 0.0 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CEH15119.1 - 0.0044 15.6 0.2 1.5 7.3 0.0 2.6 2 1 1 3 3 3 2 Adaptin N terminal region MMS19_N PF14500.6 CEH15119.1 - 0.047 13.3 0.2 0.095 12.3 0.2 1.4 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II DAO PF01266.24 CEH15120.1 - 2.3e-50 172.1 2.2 2.6e-50 172.0 2.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEH15120.1 - 0.0079 16.4 1.0 0.049 13.9 0.3 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CEH15120.1 - 0.082 13.5 0.5 27 5.4 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DSBA PF01323.20 CEH15121.1 - 8e-32 110.6 0.1 9.1e-32 110.4 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain CDC50 PF03381.15 CEH15122.1 - 6.1e-90 301.5 0.0 7.5e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family VMA21 PF09446.10 CEH15122.1 - 1.6 8.9 4.7 1 9.5 1.9 2.0 2 0 0 2 2 2 0 VMA21-like domain pPIWI_RE_Z PF18155.1 CEH15123.1 - 0.043 13.7 0.1 0.05 13.5 0.1 1.0 1 0 0 1 1 1 0 pPIWI RE three-gene island domain Z RabGAP-TBC PF00566.18 CEH15125.1 - 7.2e-19 68.3 0.0 6e-09 35.9 0.0 3.1 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Response_reg PF00072.24 CEH15126.1 - 2e-19 69.8 0.0 3.7e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 CEH15126.1 - 3.6e-15 56.5 0.0 6.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CEH15126.1 - 9.8e-06 25.5 0.1 2.6e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 CEH15126.1 - 0.017 14.9 0.0 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_2 PF12796.7 CEH15127.1 - 4.4e-13 49.6 0.0 2.7e-06 27.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CEH15127.1 - 2e-08 34.3 0.1 4.7e-05 23.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CEH15127.1 - 1.8e-06 28.4 0.1 0.00049 20.6 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEH15127.1 - 2.6e-06 27.3 0.0 0.00097 19.4 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 CEH15127.1 - 4.7e-06 26.8 0.0 1.4e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) FSH1 PF03959.13 CEH15128.1 - 2.3e-14 53.6 0.0 2.9e-13 50.0 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF4477 PF14780.6 CEH15128.1 - 0.0098 15.5 0.1 0.022 14.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4477) PigN PF04987.14 CEH15129.1 - 1.1e-113 380.6 8.6 1.5e-113 380.1 8.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Sulfatase PF00884.23 CEH15129.1 - 5.1e-05 22.8 0.1 8.9e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CEH15129.1 - 0.00031 20.4 1.1 0.0045 16.6 0.3 2.4 1 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CEH15129.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF4231 PF14015.6 CEH15129.1 - 1.4 9.5 3.7 2.7 8.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) RNase_P_Rpp14 PF01900.19 CEH15130.1 - 2.3e-19 69.5 0.1 3.2e-19 69.1 0.1 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Cofac_haem_bdg PF04187.13 CEH15131.1 - 1e-21 77.9 0.0 6.4e-14 52.5 0.0 3.1 2 2 0 2 2 2 2 Haem-binding uptake, Tiki superfamily, ChaN adh_short PF00106.25 CEH15132.1 - 5.6e-47 159.7 1.5 7.5e-47 159.3 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH15132.1 - 8.2e-30 104.1 0.6 1e-29 103.8 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH15132.1 - 2.3e-10 40.7 0.5 3e-10 40.3 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEH15132.1 - 0.0032 17.0 0.5 0.006 16.1 0.1 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CEH15132.1 - 0.0048 16.1 0.2 0.0063 15.7 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 CEH15132.1 - 0.029 14.1 0.6 0.075 12.8 0.6 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.18 CEH15132.1 - 0.035 14.0 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 CEH15132.1 - 0.066 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 CEH15132.1 - 0.078 12.6 0.3 0.15 11.7 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 CEH15132.1 - 0.085 12.1 0.2 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain AA_permease_2 PF13520.6 CEH15133.1 - 1e-50 172.9 38.5 1.1e-46 159.6 29.7 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 CEH15133.1 - 8.8e-15 54.3 33.0 2.3e-11 43.0 16.0 3.0 3 0 0 3 3 3 3 Amino acid permease GWT1 PF06423.12 CEH15133.1 - 1.1 9.4 6.2 0.55 10.3 0.4 2.9 1 1 1 2 2 2 0 GWT1 PET117 PF15786.5 CEH15134.1 - 2.7e-17 62.8 5.0 2.3e-16 59.8 5.0 1.9 1 1 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial SR-25 PF10500.9 CEH15134.1 - 0.0021 17.7 1.5 0.0025 17.5 1.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.16 CEH15134.1 - 0.048 13.7 0.0 0.053 13.6 0.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PCRF PF03462.18 CEH15135.1 - 3.5e-42 144.5 0.7 3.5e-42 144.5 0.7 2.0 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CEH15135.1 - 5.3e-35 119.8 6.6 1.7e-34 118.3 6.6 1.9 1 0 0 1 1 1 1 RF-1 domain R_equi_Vir PF05526.11 CEH15135.1 - 0.3 10.9 1.3 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein CMS1 PF14617.6 CEH15136.1 - 0.86 8.9 6.3 0.043 13.2 0.4 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DNA_topoisoIV PF00521.20 CEH15137.1 - 2e-130 435.5 0.0 3.4e-130 434.7 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CEH15137.1 - 1.4e-52 177.4 0.6 1.4e-52 177.4 0.6 2.4 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CEH15137.1 - 1.7e-27 96.0 2.5 3.4e-27 95.0 2.5 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CEH15137.1 - 3.4e-13 50.1 0.0 9.2e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CEH15137.1 - 7.7e-08 32.5 0.0 2.9e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Toprim domain NusA_N PF08529.11 CEH15137.1 - 0.51 10.7 4.7 0.41 11.0 0.2 3.1 3 1 0 3 3 3 0 NusA N-terminal domain Na_Ca_ex PF01699.24 CEH15138.1 - 2.3e-13 50.3 34.3 3.5e-08 33.5 11.4 2.6 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Caveolin PF01146.17 CEH15138.1 - 0.34 10.9 0.1 0.34 10.9 0.1 2.5 3 0 0 3 3 3 0 Caveolin ATG_C PF09333.11 CEH15139.1 - 6.6e-25 87.3 0.4 2.5e-24 85.4 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 CEH15139.1 - 1.1e-08 35.0 0.0 5.8e-08 32.6 0.0 2.3 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.7 CEH15139.1 - 4.5e-08 33.2 0.0 1.7e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CEH15139.1 - 0.0002 21.2 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal EF-hand_4 PF12763.7 CEH15140.1 - 2e-33 114.4 0.0 6.7e-13 48.5 0.0 3.3 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 CEH15140.1 - 8.1e-07 28.8 0.0 1.7e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.6 CEH15140.1 - 0.00012 22.4 0.0 0.54 10.7 0.0 3.7 2 1 0 2 2 2 1 EF-hand domain pair UBA_3 PF09288.10 CEH15140.1 - 0.00031 20.5 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain EF-hand_1 PF00036.32 CEH15140.1 - 0.0013 18.2 0.0 7 6.5 0.0 4.1 4 0 0 4 4 4 0 EF hand zf-C4H2 PF10146.9 CEH15140.1 - 0.0052 17.1 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 Zinc finger-containing protein EF-hand_6 PF13405.6 CEH15140.1 - 0.025 14.5 2.1 39 4.5 0.0 4.9 6 0 0 6 6 4 0 EF-hand domain ATG16 PF08614.11 CEH15140.1 - 0.05 13.8 25.7 4.1 7.6 24.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 CEH15140.1 - 0.17 11.2 18.3 0.26 10.6 6.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 CEH15140.1 - 0.21 10.1 9.9 0.29 9.6 9.9 1.1 1 0 0 1 1 1 0 Macoilin family Mto2_bdg PF12808.7 CEH15140.1 - 0.47 10.8 7.1 0.11 12.8 2.7 2.2 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Spc7 PF08317.11 CEH15140.1 - 0.52 9.1 19.1 0.62 8.9 18.3 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF812 PF05667.11 CEH15140.1 - 0.6 8.9 13.8 0.88 8.4 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tup_N PF08581.10 CEH15140.1 - 0.6 10.4 8.6 0.55 10.6 4.6 2.2 2 0 0 2 2 2 0 Tup N-terminal TSC22 PF01166.18 CEH15140.1 - 0.69 10.3 3.1 0.91 9.9 1.9 1.8 2 0 0 2 2 1 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 CEH15140.1 - 0.84 9.7 21.4 5.2 7.1 21.2 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phlebovirus_NSM PF07246.11 CEH15140.1 - 0.89 8.9 6.5 1.4 8.2 6.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CtIP_N PF10482.9 CEH15140.1 - 1.2 9.2 8.5 2.4 8.2 8.5 1.4 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain APG6_N PF17675.1 CEH15140.1 - 1.8 9.1 21.7 1.5 9.3 4.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-Q PF13094.6 CEH15140.1 - 2.8 8.1 23.7 0.33 11.1 4.9 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit YabA PF06156.13 CEH15140.1 - 3.2 8.4 11.6 0.36 11.5 4.7 2.2 1 1 2 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 CEH15140.1 - 3.5 8.0 19.0 16 5.9 19.1 1.8 1 1 0 1 1 1 0 Fez1 bZIP_1 PF00170.21 CEH15140.1 - 4 7.6 10.3 0.46 10.6 3.2 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF4201 PF13870.6 CEH15140.1 - 4.5 7.0 17.2 9.7 5.9 12.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) MscS_porin PF12795.7 CEH15140.1 - 4.7 6.7 26.9 5.9 6.4 1.8 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Lebercilin PF15619.6 CEH15140.1 - 5.2 6.7 20.8 3.5 7.3 14.9 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TPR_MLP1_2 PF07926.12 CEH15140.1 - 5.9 7.0 22.4 0.85 9.7 17.8 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 CEH15140.1 - 6.4 7.0 7.4 12 6.1 7.4 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family BRE1 PF08647.11 CEH15140.1 - 7.4 6.7 20.1 9.5 6.4 12.2 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Pox_A_type_inc PF04508.12 CEH15142.1 - 0.083 12.8 0.9 11 6.0 0.6 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Laminin_II PF06009.12 CEH15142.1 - 0.092 12.8 0.4 0.092 12.8 0.4 2.6 1 1 2 3 3 3 0 Laminin Domain II MscS_porin PF12795.7 CEH15142.1 - 0.16 11.5 12.7 0.15 11.6 6.7 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF4200 PF13863.6 CEH15142.1 - 0.16 12.4 12.1 0.34 11.3 6.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Exonuc_VII_L PF02601.15 CEH15142.1 - 0.28 10.7 7.1 0.42 10.1 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec8_exocyst PF04048.14 CEH15142.1 - 0.92 9.4 4.3 9.7 6.1 0.4 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ADIP PF11559.8 CEH15142.1 - 1.5 8.9 14.2 0.22 11.6 4.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 CEH15142.1 - 4.7 6.6 14.4 15 4.9 14.5 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 MRPL52 PF18699.1 CEH15142.1 - 10 6.4 8.0 1.5 9.0 3.5 1.9 2 0 0 2 2 2 0 Mitoribosomal protein mL52 IglC PF11550.8 CEH15143.1 - 0.16 11.4 0.3 0.25 10.8 0.3 1.2 1 0 0 1 1 1 0 Intracellular growth locus C protein Zn_ribbon_17 PF17120.5 CEH15144.1 - 3.9e-05 23.2 3.0 7.7e-05 22.2 3.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type C1_2 PF03107.16 CEH15144.1 - 0.0031 17.8 3.6 0.0056 17.0 0.9 2.2 2 0 0 2 2 2 1 C1 domain C1_1 PF00130.22 CEH15144.1 - 0.034 14.0 2.0 0.034 14.0 2.0 1.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 CEH15144.1 - 0.044 13.7 6.3 0.17 11.8 6.3 1.9 1 1 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 CEH15144.1 - 0.17 12.2 8.7 0.62 10.4 8.7 1.9 1 1 0 1 1 1 0 Ring finger domain zf-HC5HC2H PF13771.6 CEH15144.1 - 0.34 11.2 4.1 0.8 10.0 4.1 1.5 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.8 CEH15144.1 - 0.36 11.0 2.1 0.63 10.3 2.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 CEH15144.1 - 0.38 10.7 5.2 0.056 13.4 1.2 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 CEH15144.1 - 1.7 8.8 8.5 0.9 9.7 3.7 2.3 1 1 1 2 2 2 0 PHD-finger DUF4449 PF14613.6 CEH15145.1 - 0.0012 19.0 3.5 0.0012 19.0 3.5 4.1 2 1 0 3 3 3 1 Protein of unknown function (DUF4449) JHBP PF06585.11 CEH15145.1 - 0.0086 15.3 0.2 0.016 14.4 0.2 1.4 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) Pkinase PF00069.25 CEH15148.1 - 6.8e-66 222.3 0.0 7.9e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15148.1 - 6.7e-33 114.1 0.0 8.5e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH15148.1 - 6.6e-07 28.9 0.0 8.1e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like PUF PF00806.19 CEH15149.1 - 4e-06 26.2 0.0 0.0074 15.9 0.0 3.0 2 0 0 2 2 2 2 Pumilio-family RNA binding repeat Gon7 PF08738.10 CEH15150.1 - 0.079 13.1 4.7 0.25 11.4 4.6 2.0 1 1 0 1 1 1 0 Gon7 family Parathyroid PF01279.17 CEH15150.1 - 0.33 11.6 3.0 2.9 8.6 0.1 3.0 2 1 0 2 2 2 0 Parathyroid hormone family Robl_LC7 PF03259.17 CEH15151.1 - 2.1 8.2 5.1 29 4.5 0.2 3.3 2 0 0 2 2 2 0 Roadblock/LC7 domain DUF2781 PF10914.8 CEH15152.1 - 5e-22 78.9 5.1 1.9e-20 73.7 5.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) TadE PF07811.12 CEH15152.1 - 0.13 12.6 0.7 0.35 11.2 0.7 1.7 1 0 0 1 1 1 0 TadE-like protein Tafi-CsgC PF10610.9 CEH15153.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Thin aggregative fimbriae synthesis protein zf-RING_2 PF13639.6 CEH15154.1 - 4.1e-10 39.8 1.0 6.3e-10 39.2 1.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEH15154.1 - 9.4e-09 35.4 0.4 1.6e-08 34.7 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEH15154.1 - 1e-07 31.6 1.8 1.5e-07 31.1 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEH15154.1 - 2e-06 27.5 0.8 3.2e-06 26.9 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH15154.1 - 5.8e-06 26.2 0.3 8.8e-06 25.6 0.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEH15154.1 - 1.1e-05 25.2 0.3 1.7e-05 24.6 0.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEH15154.1 - 1.8e-05 24.5 0.5 2.9e-05 23.8 0.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEH15154.1 - 6.1e-05 23.0 0.1 9e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CEH15154.1 - 0.00017 21.3 0.1 0.00017 21.3 0.1 1.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CEH15154.1 - 0.0031 17.5 1.4 0.0031 17.5 1.4 1.5 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CEH15154.1 - 0.0036 16.9 1.2 0.01 15.5 1.3 1.7 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 CEH15154.1 - 0.085 13.0 0.8 0.17 12.0 0.8 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 CEH15154.1 - 0.13 12.0 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CDC24_OB3 PF17244.2 CEH15154.1 - 0.15 11.8 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 zf-C3H2C3 PF17122.5 CEH15154.1 - 0.31 11.1 4.2 0.63 10.1 4.2 1.5 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 CEH15154.1 - 0.43 10.8 4.2 9.3 6.5 4.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain DUF2849 PF11011.8 CEH15154.1 - 3.8 8.2 7.2 0.27 11.9 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) HpcH_HpaI PF03328.14 CEH15156.1 - 2.2e-15 56.4 0.0 3.5e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 CEH15156.1 - 4.7e-08 32.6 0.0 7.8e-08 31.8 0.0 1.3 1 1 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold ADIP PF11559.8 CEH15158.1 - 0.0068 16.5 7.9 0.0077 16.3 7.9 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Striatin PF08232.12 CEH15158.1 - 0.014 16.0 4.0 0.017 15.7 4.0 1.2 1 0 0 1 1 1 0 Striatin family Shugoshin_N PF07558.11 CEH15158.1 - 0.014 15.3 8.9 1.3 8.9 8.8 2.9 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 CEH15158.1 - 0.041 14.5 3.4 0.051 14.2 3.4 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 CEH15158.1 - 0.053 13.3 7.2 1.6 8.5 0.3 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF2205 PF10224.9 CEH15158.1 - 0.083 12.9 5.5 0.49 10.4 4.6 2.0 1 1 1 2 2 2 0 Short coiled-coil protein Fzo_mitofusin PF04799.13 CEH15158.1 - 0.088 12.4 1.5 0.091 12.3 1.5 1.2 1 0 0 1 1 1 0 fzo-like conserved region FlaC_arch PF05377.11 CEH15158.1 - 0.12 12.8 3.0 3.8 8.0 0.2 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 CEH15158.1 - 0.63 10.4 6.4 7.9 6.9 4.1 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family CCDC-167 PF15188.6 CEH15158.1 - 1 9.7 6.8 9.6 6.6 6.8 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 M PF02370.16 CEH15158.1 - 3.1 8.7 6.2 7.4 7.5 0.3 3.2 3 1 1 4 4 4 0 M protein repeat Hs1pro-1_C PF07014.12 CEH15159.1 - 0.039 13.4 0.1 0.045 13.2 0.1 1.0 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus MecA_N PF05223.11 CEH15159.1 - 0.043 14.1 0.2 0.05 13.9 0.2 1.1 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain AD PF09793.9 CEH15159.1 - 0.12 12.5 0.9 0.16 12.1 0.9 1.4 1 1 0 1 1 1 0 Anticodon-binding domain Quaking_NLS PF16551.5 CEH15161.1 - 0.18 11.5 1.5 0.27 11.0 0.2 1.9 2 0 0 2 2 2 0 Putative nuclear localisation signal of quaking EB PF01683.18 CEH15163.1 - 0.032 14.5 2.7 0.042 14.2 0.1 2.1 2 0 0 2 2 2 0 EB module TFX_C PF14601.6 CEH15165.1 - 0.064 13.2 0.0 0.8 9.7 0.0 2.2 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term FMO-like PF00743.19 CEH15168.1 - 4.2e-19 68.4 0.1 1.4e-15 56.7 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 CEH15168.1 - 2e-12 46.9 1.5 1e-09 38.1 0.1 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CEH15168.1 - 3.6e-09 36.3 0.4 1.2e-06 28.0 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEH15168.1 - 1.8e-07 30.7 0.3 7e-06 25.5 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEH15168.1 - 2.1e-06 27.9 1.6 1.6e-05 25.0 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEH15168.1 - 3e-06 27.0 5.9 0.18 11.4 0.1 3.2 2 1 1 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEH15168.1 - 2.9e-05 24.1 2.6 0.005 16.8 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CEH15168.1 - 0.027 15.0 1.2 7.3 7.2 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEH15168.1 - 0.051 12.8 0.8 0.14 11.4 0.2 1.8 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.15 CEH15168.1 - 0.066 11.8 0.1 0.43 9.1 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 CEH15168.1 - 0.086 11.9 0.1 0.086 11.9 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 CEH15168.1 - 0.2 10.7 2.9 2.6 7.0 0.0 2.3 1 1 1 2 2 2 0 FAD binding domain KR PF08659.10 CEH15169.1 - 3.7e-25 88.9 1.5 8.8e-25 87.7 1.5 1.6 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 CEH15169.1 - 2.1e-10 40.8 0.2 6.8e-10 39.2 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thioesterase PF00975.20 CEH15169.1 - 5.7e-09 36.4 0.0 1.2e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PSD3 PF07626.11 CEH15169.1 - 0.023 15.2 0.0 1.3 9.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) adh_short_C2 PF13561.6 CEH15169.1 - 0.024 14.2 1.6 0.25 10.9 0.9 2.5 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH15169.1 - 0.053 13.0 1.7 0.25 10.8 1.7 2.1 1 1 0 1 1 1 0 short chain dehydrogenase Symplekin_C PF12295.8 CEH15171.1 - 2.6e-53 180.9 0.0 8.2e-53 179.3 0.0 1.9 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 CEH15171.1 - 7.7e-35 120.6 0.4 1.9e-34 119.3 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) DUF4310 PF14187.6 CEH15171.1 - 0.19 11.4 1.1 0.36 10.4 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) DUF1764 PF08576.10 CEH15172.1 - 1.4e-08 35.6 0.8 3.3e-07 31.1 0.4 2.4 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) RGS_DHEX PF18148.1 CEH15172.1 - 0.058 13.5 0.7 0.16 12.1 0.3 1.8 1 1 1 2 2 2 0 Regulator of G-protein signalling DHEX domain CLP1_P PF16575.5 CEH15173.1 - 2.1e-19 70.0 0.0 1.4e-08 34.8 0.0 3.9 3 1 0 3 3 3 3 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 CEH15173.1 - 0.0031 17.6 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.13 CEH15173.1 - 0.036 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 CEH15173.1 - 0.063 13.7 0.8 0.21 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 CEH15173.1 - 0.13 12.3 0.1 0.33 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain LRIF1 PF15741.5 CEH15173.1 - 0.94 7.9 6.9 1.4 7.3 6.9 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 GREB1 PF15782.5 CEH15173.1 - 1.2 6.2 7.7 1.8 5.6 7.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CEH15173.1 - 8.1 4.9 11.5 16 3.9 11.5 1.4 1 0 0 1 1 1 0 Macoilin family Sld5 PF05916.11 CEH15174.1 - 0.0058 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein DAO PF01266.24 CEH15175.1 - 2.4e-36 126.1 0.2 3.3e-36 125.6 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEH15175.1 - 4.6e-10 39.2 0.0 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEH15175.1 - 7.7e-09 35.1 0.1 0.00015 21.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 CEH15175.1 - 9.7e-09 34.9 0.1 1.2e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 CEH15175.1 - 4.6e-07 30.3 0.0 3.9e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEH15175.1 - 6.7e-07 29.5 0.3 2.5e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CEH15175.1 - 1.6e-06 27.1 0.0 0.013 14.2 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 CEH15175.1 - 9.2e-05 22.5 0.0 0.32 11.0 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 CEH15175.1 - 0.00011 21.7 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 CEH15175.1 - 0.00051 20.0 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CEH15175.1 - 0.0011 18.2 0.0 1.4 7.9 0.0 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CEH15175.1 - 0.0014 17.9 0.0 0.03 13.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 CEH15175.1 - 0.0017 18.6 0.0 0.0042 17.3 0.0 1.7 2 0 0 2 2 1 1 TrkA-N domain K_oxygenase PF13434.6 CEH15175.1 - 0.0022 17.2 0.0 0.49 9.5 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 CEH15175.1 - 0.0089 15.1 0.1 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 CEH15175.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 CEH15175.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CEH15175.1 - 0.015 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 CEH15175.1 - 0.017 14.4 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Glyco_transf_4 PF13439.6 CEH15175.1 - 0.023 14.7 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 NAD_binding_2 PF03446.15 CEH15175.1 - 0.043 14.0 0.0 0.095 12.9 0.0 1.6 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 CEH15175.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF364 PF04016.12 CEH15175.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative heavy-metal chelation NAD_binding_7 PF13241.6 CEH15175.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding YjgF_endoribonc PF14588.6 CEH15176.1 - 0.069 13.3 0.0 8.5 6.5 0.0 2.3 2 0 0 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease MutS_V PF00488.21 CEH15177.1 - 8.7e-66 221.5 0.2 1.5e-65 220.8 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CEH15177.1 - 5.2e-35 121.4 1.8 2e-33 116.2 0.2 2.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CEH15177.1 - 3.4e-34 117.5 0.0 8.2e-34 116.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CEH15177.1 - 3.1e-13 50.2 0.0 7.6e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II zf-C2H2_3 PF13878.6 CEH15177.1 - 1.9e-11 43.6 0.3 4.3e-11 42.4 0.3 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_13 PF13880.6 CEH15177.1 - 2.7e-11 43.3 0.0 6.6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase MutS_IV PF05190.18 CEH15177.1 - 0.0013 19.0 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_30 PF13604.6 CEH15177.1 - 0.042 13.6 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 CEH15177.1 - 0.057 13.7 0.1 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Transglut_core3 PF13471.6 CEH15177.1 - 0.11 12.4 0.2 1.8 8.5 0.0 3.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily Rnk_N PF14760.6 CEH15177.1 - 0.95 10.0 3.6 13 6.3 2.6 3.2 3 0 0 3 3 3 0 Rnk N-terminus TMF_TATA_bd PF12325.8 CEH15184.1 - 0.0084 16.3 2.6 0.01 16.0 2.2 1.3 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding LMP PF04778.12 CEH15184.1 - 0.025 14.5 1.0 0.025 14.5 1.0 1.2 1 0 0 1 1 1 0 LMP repeated region BRE1 PF08647.11 CEH15184.1 - 0.031 14.3 3.7 0.04 14.0 2.8 1.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase HIP1_clath_bdg PF16515.5 CEH15184.1 - 0.035 14.7 4.9 0.041 14.5 4.9 1.1 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 CEH15184.1 - 0.092 12.8 0.8 0.11 12.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ADIP PF11559.8 CEH15185.1 - 0.0011 19.1 16.5 0.0043 17.2 15.3 1.9 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding DUF2968 PF11180.8 CEH15185.1 - 0.0019 17.8 18.1 0.0022 17.6 18.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) ATG16 PF08614.11 CEH15185.1 - 0.007 16.6 16.6 0.0084 16.4 16.6 1.2 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CEH15185.1 - 0.037 14.6 16.6 0.048 14.2 16.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 CEH15185.1 - 0.046 13.7 16.9 0.066 13.2 16.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 CEH15185.1 - 0.06 13.8 17.6 0.44 11.0 4.4 2.2 1 1 1 2 2 2 0 Cell division protein ZapB DUF3073 PF11273.8 CEH15185.1 - 0.082 13.7 8.1 2.3 9.0 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) DUF1664 PF07889.12 CEH15185.1 - 0.19 11.7 4.6 0.19 11.8 3.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 CEH15185.1 - 0.23 11.2 14.6 1.7 8.5 3.8 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4164 PF13747.6 CEH15185.1 - 0.36 11.1 12.9 0.075 13.3 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF4094 PF13334.6 CEH15185.1 - 0.4 11.1 6.3 0.95 9.9 6.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) CLZ PF16526.5 CEH15185.1 - 0.47 10.8 8.9 0.14 12.5 5.2 2.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Golgin_A5 PF09787.9 CEH15185.1 - 0.55 9.6 16.7 0.66 9.4 16.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 HAUS6_N PF14661.6 CEH15185.1 - 1 8.9 11.1 1.1 8.8 11.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus UPF0242 PF06785.11 CEH15185.1 - 1.8 8.7 15.3 2.2 8.3 15.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_Maf PF03131.17 CEH15185.1 - 1.8 9.1 13.1 5.6 7.5 2.9 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor Tho2 PF11262.8 CEH15185.1 - 3.6 6.7 8.8 5.9 6.0 8.8 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spc7 PF08317.11 CEH15185.1 - 3.8 6.3 16.5 4.5 6.1 16.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CEH15186.1 - 3.2 7.8 34.4 1.4 8.9 2.3 4.1 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LOH1CR12 PF10158.9 CEH15188.1 - 2.3e-05 24.4 0.3 0.61 10.1 0.0 3.0 1 1 2 3 3 3 2 Tumour suppressor protein Ribosom_S12_S23 PF00164.25 CEH15188.1 - 6.7e-05 22.5 0.1 0.28 10.8 0.0 2.5 1 1 2 3 3 3 2 Ribosomal protein S12/S23 DUF1727 PF08353.10 CEH15188.1 - 0.00077 19.4 0.1 0.19 11.7 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1727) DASH_Dad3 PF08656.10 CEH15188.1 - 0.015 15.4 0.0 18 5.5 0.0 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad3 OKR_DC_1_C PF03711.15 CEH15188.1 - 0.023 15.0 0.2 1.7 8.9 0.0 2.3 1 1 1 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain MTS_N PF08468.11 CEH15188.1 - 0.023 14.7 1.5 3.8 7.6 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal Lipase_3 PF01764.25 CEH15188.1 - 0.032 14.1 0.1 16 5.4 0.0 2.7 2 1 1 3 3 3 0 Lipase (class 3) DUF5082 PF16888.5 CEH15188.1 - 0.036 14.3 0.0 2.3 8.5 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Tape_meas_lam_C PF09718.10 CEH15188.1 - 0.042 14.0 2.2 3.6 7.8 0.1 2.9 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Nup88 PF10168.9 CEH15188.1 - 0.059 11.2 0.0 0.11 10.3 0.0 1.3 1 1 0 1 1 1 0 Nuclear pore component SLATT_6 PF18169.1 CEH15189.1 - 0.27 10.8 0.0 0.51 9.9 0.0 1.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 PTH2 PF01981.16 CEH15191.1 - 9.9e-47 158.1 0.2 1.5e-46 157.5 0.2 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 C6 PF01681.17 CEH15191.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 C6 domain BNIP3 PF06553.12 CEH15191.1 - 2.8 7.6 5.3 1 9.0 0.1 2.3 2 1 1 3 3 3 0 BNIP3 PC_rep PF01851.22 CEH15192.1 - 2.5e-42 141.2 21.2 9.1e-10 38.5 0.0 8.5 8 0 0 8 8 8 7 Proteasome/cyclosome repeat RPN2_C PF18004.1 CEH15192.1 - 2.9e-42 144.3 3.4 1.1e-41 142.4 3.0 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 CEH15192.1 - 1.8e-18 66.7 5.7 1.9e-13 50.6 0.1 4.5 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 CEH15192.1 - 0.00039 20.9 2.3 0.79 10.3 0.1 5.2 3 1 1 4 4 4 1 HEAT-like repeat HEAT PF02985.22 CEH15192.1 - 0.00048 20.2 5.4 1 9.8 0.1 5.6 8 0 0 8 8 6 2 HEAT repeat HEAT_PBS PF03130.16 CEH15192.1 - 0.0035 17.9 3.7 37 5.4 0.0 5.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Utp13 PF08625.11 CEH15192.1 - 0.014 15.3 0.1 0.057 13.3 0.1 2.1 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Cnd1 PF12717.7 CEH15192.1 - 0.11 12.6 0.0 1.8 8.6 0.0 2.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Vfa1 PF08432.10 CEH15192.1 - 0.14 12.5 3.3 0.31 11.3 3.3 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TPR_4 PF07721.14 CEH15192.1 - 0.17 12.6 1.3 11 7.0 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 CEH15192.1 - 0.71 10.1 4.5 10 6.4 0.1 4.1 4 1 1 5 5 5 0 Tetratrico peptide repeat DUF3140 PF11338.8 CEH15193.1 - 0.0027 18.1 0.0 0.0042 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) Dynamin_N PF00350.23 CEH15194.1 - 8e-18 65.1 0.9 2.4e-17 63.5 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CEH15194.1 - 3.4e-12 46.5 0.0 1.8e-11 44.1 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEH15194.1 - 3.5e-08 33.2 0.1 2e-05 24.2 0.1 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEH15194.1 - 4e-05 23.6 1.3 0.19 11.6 0.2 2.9 2 1 1 3 3 3 2 RsgA GTPase cobW PF02492.19 CEH15194.1 - 0.0023 17.6 0.1 0.32 10.6 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CEH15194.1 - 0.0064 16.7 0.0 0.7 10.1 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH15194.1 - 0.0069 15.9 0.4 0.81 9.1 0.0 2.6 2 0 0 2 2 2 1 ADP-ribosylation factor family IIGP PF05049.13 CEH15194.1 - 0.011 14.9 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 CEH15194.1 - 0.017 15.5 0.0 0.061 13.7 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CEH15194.1 - 0.02 14.7 0.8 0.062 13.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 CEH15194.1 - 0.02 14.9 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NicO PF03824.16 CEH15194.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein AAA_18 PF13238.6 CEH15194.1 - 0.11 13.0 0.1 4.6 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 CEH15195.1 - 5.5e-46 156.5 0.0 1.9e-45 154.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH15195.1 - 2.8e-30 104.9 0.0 3.3e-29 101.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MMR_HSR1 PF01926.23 CEH15196.1 - 5e-16 58.8 0.4 1.4e-13 50.9 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH15196.1 - 2.6e-07 30.3 0.1 5.5e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CEH15196.1 - 3.1e-07 30.1 0.0 0.00031 20.3 0.0 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEH15196.1 - 4e-05 23.6 0.1 0.005 16.8 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CEH15196.1 - 0.0022 18.1 1.3 0.82 9.7 0.5 3.3 2 1 1 3 3 3 1 Dynamin family AAA_18 PF13238.6 CEH15196.1 - 0.0058 17.2 0.0 0.017 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Virul_Fac PF10139.9 CEH15196.1 - 0.0063 14.8 0.5 0.012 13.9 0.5 1.3 1 0 0 1 1 1 1 Putative bacterial virulence factor AIG1 PF04548.16 CEH15196.1 - 0.098 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 CEH15196.1 - 0.099 12.1 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit B-block_TFIIIC PF04182.12 CEH15197.1 - 3.4e-06 27.1 0.0 2.9e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_micro PF17007.5 CEH15197.1 - 0.034 13.0 0.0 0.085 11.7 0.0 1.6 1 0 0 1 1 1 0 HTH-like HTH_20 PF12840.7 CEH15197.1 - 0.064 13.3 0.0 0.24 11.5 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 CEH15197.1 - 0.085 12.8 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 MarR family Raftlin PF15250.6 CEH15197.1 - 0.81 8.4 5.5 9.3 4.9 0.1 2.7 2 0 0 2 2 2 0 Raftlin AT_hook PF02178.19 CEH15197.1 - 0.83 9.7 5.0 3.3 7.9 5.0 2.1 1 0 0 1 1 1 0 AT hook motif CIAPIN1 PF05093.13 CEH15199.1 - 1e-30 106.2 6.4 1e-30 106.2 6.4 2.3 2 1 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 CEH15199.1 - 1.6e-06 28.4 0.0 2.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus DUF4203 PF13886.6 CEH15200.1 - 0.00013 21.7 0.2 0.00085 19.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) LIP PF03583.14 CEH15203.1 - 1e-41 143.1 0.0 1.5e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Lipase_3 PF01764.25 CEH15203.1 - 0.055 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) His_Phos_1 PF00300.22 CEH15205.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) mRNA_cap_C PF03919.15 CEH15206.1 - 1.2e-15 58.1 0.2 2.5e-14 53.8 0.2 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain mRNA_cap_enzyme PF01331.19 CEH15207.1 - 5.4e-29 101.4 0.0 8.3e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 CEH15207.1 - 3.6e-06 26.8 0.0 0.043 13.4 0.0 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 CEH15207.1 - 0.0024 18.2 0.0 0.0031 17.8 0.0 1.2 1 0 0 1 1 1 1 RNA ligase DNA_pol_E_B PF04042.16 CEH15208.1 - 2e-45 154.7 0.1 2.9e-45 154.2 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PPR_2 PF13041.6 CEH15209.1 - 0.00026 21.1 0.0 0.12 12.6 0.0 3.5 2 1 1 3 3 3 2 PPR repeat family Proteasome PF00227.26 CEH15210.1 - 1.1e-49 168.5 0.1 1.4e-49 168.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit NTP_transferase PF00483.23 CEH15211.1 - 2.3e-38 132.2 0.0 2.2e-37 129.0 0.0 2.2 1 1 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.18 CEH15211.1 - 3.5e-06 27.0 1.1 5e-06 26.5 0.3 1.7 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Zw10 PF06248.13 CEH15212.1 - 3.1e-06 26.1 0.0 1.1e-05 24.3 0.0 1.8 3 0 0 3 3 3 1 Centromere/kinetochore Zw10 YscO PF07321.12 CEH15212.1 - 0.59 10.1 0.0 0.59 10.1 0.0 4.0 4 0 0 4 4 4 0 Type III secretion protein YscO HECT PF00632.25 CEH15213.1 - 2e-94 316.5 0.0 2.7e-94 316.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CEH15213.1 - 1.8e-34 117.4 18.0 3.6e-12 46.1 2.6 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.30 CEH15213.1 - 8.8e-21 74.1 0.2 2.1e-20 72.9 0.2 1.6 1 0 0 1 1 1 1 C2 domain S10_plectin PF03501.15 CEH15215.1 - 6.1e-42 141.6 0.0 7.4e-42 141.3 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Ribosomal_L44 PF00935.19 CEH15216.1 - 1.3e-35 121.7 11.6 2e-35 121.1 11.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L34e PF01199.18 CEH15217.1 - 1.1e-42 144.2 5.2 1.5e-42 143.8 5.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.6 CEH15217.1 - 0.0093 16.0 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c FhuF_C PF11575.8 CEH15217.1 - 0.29 11.1 4.1 6.6 6.8 0.1 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Ribosomal_S30 PF04758.14 CEH15218.1 - 1.5e-28 98.8 8.6 1.6e-28 98.6 8.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S14 PF00253.21 CEH15219.1 - 1.1e-15 57.1 1.3 1.5e-15 56.7 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Vps51 PF08700.11 CEH15226.1 - 4.8e-10 39.4 0.0 2.6e-09 37.0 0.0 2.3 1 0 0 1 1 1 1 Vps51/Vps67 MarR_2 PF12802.7 CEH15226.1 - 0.01 15.7 0.4 3.8 7.5 0.1 2.9 2 0 0 2 2 2 0 MarR family DUF2383 PF09537.10 CEH15226.1 - 0.046 14.1 1.5 0.17 12.2 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Apo-VLDL-II PF05418.11 CEH15226.1 - 0.15 12.6 0.0 0.41 11.3 0.0 1.6 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) FlgN PF05130.12 CEH15226.1 - 2.8 8.4 12.6 0.38 11.2 4.0 3.5 3 0 0 3 3 3 0 FlgN protein WD40 PF00400.32 CEH15227.1 - 1.6e-16 60.4 18.3 0.0012 19.7 0.2 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 CEH15227.1 - 0.085 12.9 0.0 0.58 10.2 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region POT1PC PF16686.5 CEH15228.1 - 1.2e-12 48.0 0.0 2.4e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 CEH15228.1 - 7.2e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 DZR PF12773.7 CEH15228.1 - 0.12 12.5 0.9 0.32 11.0 0.9 1.7 1 0 0 1 1 1 0 Double zinc ribbon Apt1 PF10351.9 CEH15228.1 - 2.9 6.6 6.2 4.5 6.0 6.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3450 PF11932.8 CEH15229.1 - 0.61 9.3 17.5 0.095 12.0 10.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Cnn_1N PF07989.11 CEH15229.1 - 1.8 8.8 14.6 3.5 7.9 4.0 3.5 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 SOBP PF15279.6 CEH15229.1 - 3.4 8.2 5.8 4.8 7.7 5.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein V_ATPase_I PF01496.19 CEH15229.1 - 3.6 5.4 13.2 4.5 5.1 13.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 CEH15229.1 - 6.4 6.2 19.7 7.4 6.0 19.1 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit VSG_B PF13206.6 CEH15229.1 - 8.4 5.5 16.1 6.7 5.9 15.0 1.4 1 1 0 1 1 1 0 Trypanosomal VSG domain HIP1_clath_bdg PF16515.5 CEH15229.1 - 9.6 6.9 24.7 2.7 8.7 8.3 3.6 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 CEH15229.1 - 9.7 6.4 34.1 0.98 9.6 7.8 2.7 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DnaJ PF00226.31 CEH15233.1 - 2.8e-16 59.4 0.1 7.5e-16 58.0 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain RAC_head PF16717.5 CEH15233.1 - 2.1e-13 51.1 8.9 2.1e-13 51.1 8.9 3.0 2 1 0 2 2 2 1 Ribosome-associated complex head domain Menin PF05053.13 CEH15233.1 - 0.27 9.5 10.7 0.42 8.9 10.7 1.2 1 0 0 1 1 1 0 Menin LMBR1 PF04791.16 CEH15233.1 - 0.44 9.4 2.1 0.43 9.4 2.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MSA_2 PF00985.17 CEH15233.1 - 1.2 9.5 7.3 2.8 8.3 7.3 1.6 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DUF913 PF06025.12 CEH15233.1 - 1.7 7.6 4.5 2.8 6.8 4.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 CEH15233.1 - 4.5 7.3 11.4 1.2 9.2 6.7 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Proteasome PF00227.26 CEH15234.1 - 2.1e-46 157.8 0.0 2.9e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEH15234.1 - 6.1e-13 48.2 0.2 1.3e-12 47.1 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fungal_trans PF04082.18 CEH15235.1 - 7.9e-06 25.1 0.0 2.7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Lipase_3 PF01764.25 CEH15236.1 - 5.3e-06 26.4 0.1 0.00032 20.6 0.1 2.5 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CEH15236.1 - 0.006 17.2 2.7 0.006 17.2 2.7 3.2 3 1 1 4 4 4 1 Alpha/beta hydrolase family MMR_HSR1 PF01926.23 CEH15236.1 - 0.0071 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CEH15236.1 - 0.06 13.4 0.0 2 8.4 0.0 2.3 1 1 1 2 2 2 0 Dynamin family G10 PF01125.17 CEH15237.1 - 1.2e-64 216.5 2.6 1.3e-64 216.4 2.6 1.0 1 0 0 1 1 1 1 G10 protein RelB_N PF18506.1 CEH15237.1 - 0.0072 16.1 0.3 0.013 15.3 0.3 1.4 1 0 0 1 1 1 1 RelB Antitoxin alpha helical domain BLOC1S3 PF15753.5 CEH15239.1 - 0.0093 16.1 0.1 0.023 14.8 0.1 1.7 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF3584 PF12128.8 CEH15239.1 - 0.026 12.1 10.5 0.033 11.7 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 CEH15239.1 - 0.038 14.1 1.2 0.059 13.5 1.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YwqJ-deaminase PF14431.6 CEH15239.1 - 0.12 12.6 1.7 0.21 11.8 0.2 2.0 1 1 0 2 2 2 0 YwqJ-like deaminase Atg14 PF10186.9 CEH15239.1 - 4.8 6.2 7.8 4.4 6.3 6.7 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4512 PF14975.6 CEH15239.1 - 5.2 7.9 5.4 37 5.2 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) IHABP4_N PF16174.5 CEH15239.1 - 6.1 7.4 14.2 0.19 12.3 6.4 2.2 1 1 2 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal NPC1_N PF16414.5 CEH15240.1 - 1.2e-74 251.0 1.0 2.5e-74 249.9 1.0 1.5 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 CEH15240.1 - 1.7e-57 195.1 0.1 8.8e-32 110.1 0.0 3.9 3 1 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 CEH15240.1 - 2.4e-39 134.6 10.2 5.4e-21 75.0 0.2 3.1 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 CEH15240.1 - 0.012 15.5 0.5 0.026 14.4 0.5 1.5 1 0 0 1 1 1 0 Folate receptor family ACR_tran PF00873.19 CEH15240.1 - 0.76 7.3 3.3 1.1 6.8 3.3 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TFIID-18kDa PF02269.16 CEH15241.1 - 9.1e-17 60.9 0.1 3.1e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit AD PF09793.9 CEH15242.1 - 8.2e-19 67.5 0.0 1.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain GTP_EFTU PF00009.27 CEH15244.1 - 1.5e-29 102.9 0.0 2.9e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CEH15244.1 - 1.4e-19 69.9 0.8 4.4e-09 36.3 0.0 2.9 3 0 0 3 3 3 2 Elongation Factor G, domain II RF3_C PF16658.5 CEH15244.1 - 0.00044 20.1 0.0 0.0016 18.3 0.0 1.9 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain GAT PF03127.14 CEH15244.1 - 0.11 12.9 0.9 0.22 11.8 0.9 1.5 1 0 0 1 1 1 0 GAT domain RGS PF00615.19 CEH15245.1 - 9.6e-40 135.5 0.0 2e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 CEH15245.1 - 3.4e-08 33.4 0.0 3.2e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Asp PF00026.23 CEH15246.1 - 9.6e-27 94.2 0.0 1.7e-26 93.4 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Amnionless PF14828.6 CEH15246.1 - 0.064 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless NOA36 PF06524.12 CEH15247.1 - 0.0065 15.8 9.7 0.0091 15.4 9.7 1.3 1 0 0 1 1 1 1 NOA36 protein DUF370 PF04025.12 CEH15247.1 - 0.024 14.7 0.1 0.045 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF370) DNA_pol_phi PF04931.13 CEH15247.1 - 1.6 6.8 14.2 2.4 6.2 14.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi CARD PF00619.21 CEH15247.1 - 3.8 7.6 7.9 1.3 9.1 0.9 2.3 2 0 0 2 2 2 0 Caspase recruitment domain Proteasome PF00227.26 CEH15248.1 - 1.2e-32 112.9 0.0 2.1e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit AMP-binding PF00501.28 CEH15249.1 - 5.9e-70 236.0 0.0 8.1e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CEH15249.1 - 1.1e-64 218.2 0.0 1.6e-64 217.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 CEH15249.1 - 8.5e-11 42.1 0.1 4e-10 39.9 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.20 CEH15249.1 - 1.7e-08 33.6 0.0 0.0013 17.4 0.0 3.2 2 1 0 2 2 2 2 Condensation domain Epimerase PF01370.21 CEH15249.1 - 8.2e-06 25.4 0.0 2.8e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEH15249.1 - 2.4e-05 23.5 0.0 0.037 13.0 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 CEH15249.1 - 0.00066 20.6 0.6 0.0072 17.3 0.1 3.0 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 CEH15249.1 - 0.061 12.4 0.0 3.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF2370 PF10176.9 CEH15250.1 - 2.7e-72 243.1 0.0 8.3e-72 241.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF202 PF02656.15 CEH15250.1 - 0.08 13.4 2.9 0.32 11.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) TRP PF06011.12 CEH15252.1 - 1.8e-32 112.6 15.0 1.8e-32 112.6 15.0 2.3 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel PBP1_TM PF14812.6 CEH15255.1 - 0.022 15.1 0.5 0.022 15.1 0.5 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal XhlA PF10779.9 CEH15255.1 - 1 9.6 2.8 1.1 9.5 0.2 2.4 2 0 0 2 2 2 0 Haemolysin XhlA adh_short PF00106.25 CEH15256.1 - 7.6e-07 28.8 0.0 0.0072 15.8 0.0 3.1 3 0 0 3 3 3 3 short chain dehydrogenase KR PF08659.10 CEH15256.1 - 0.029 14.3 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 KR domain RAI16-like PF10257.9 CEH15260.1 - 1.2e-46 159.3 0.0 1.7e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Ank_2 PF12796.7 CEH15261.1 - 1.8e-48 163.0 0.1 1.5e-18 67.2 0.1 2.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEH15261.1 - 2.8e-28 97.6 1.3 1.2e-08 35.0 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEH15261.1 - 5.8e-24 84.2 0.3 1e-11 45.1 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEH15261.1 - 2.2e-22 76.7 0.1 0.00027 21.1 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CEH15261.1 - 5.8e-19 67.6 0.3 0.00014 22.2 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.21 CEH15261.1 - 7.4e-18 64.4 6.3 7.4e-18 64.4 6.3 2.3 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.6 CEH15261.1 - 1.4e-06 28.5 5.4 1.4e-06 28.5 5.4 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEH15261.1 - 0.00032 20.5 4.8 0.00032 20.5 4.8 3.0 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEH15261.1 - 0.0015 18.2 5.4 0.0015 18.2 5.4 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 CEH15261.1 - 0.0023 18.2 3.5 0.0023 18.2 3.5 2.6 3 0 0 3 3 3 1 RING-H2 zinc finger domain FYVE_2 PF02318.16 CEH15261.1 - 2.2 8.5 8.9 0.042 14.1 1.5 1.9 2 0 0 2 2 1 0 FYVE-type zinc finger DUF4774 PF15999.5 CEH15261.1 - 8.1 6.4 11.5 0.68 9.8 0.5 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4774) LRR_4 PF12799.7 CEH15262.1 - 2.7e-05 24.4 0.8 0.00074 19.9 0.2 2.2 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEH15262.1 - 6.2e-05 22.7 1.5 0.0028 17.4 0.4 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 CEH15262.1 - 1.3 9.8 3.9 31 5.6 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 CEH15263.1 - 2.7e-10 39.8 12.6 0.00025 20.7 0.0 3.7 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CEH15263.1 - 1.5e-09 38.0 8.5 8.4e-05 22.9 0.1 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEH15263.1 - 0.015 15.3 5.9 1.2 9.4 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.6 CEH15263.1 - 0.13 11.7 0.1 0.96 8.9 0.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 CEH15263.1 - 2.2 9.1 9.3 30 5.7 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Cupin_3 PF05899.12 CEH15265.1 - 0.00096 18.8 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 CEH15265.1 - 0.0036 17.1 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Ectoine_synth PF06339.12 CEH15265.1 - 0.059 13.6 0.1 0.069 13.3 0.1 1.2 1 0 0 1 1 1 0 Ectoine synthase Pirin_C PF05726.13 CEH15265.1 - 0.091 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Pirin C-terminal cupin domain Glyco_transf_22 PF03901.17 CEH15267.1 - 9.3e-15 54.8 5.5 1.3e-14 54.3 5.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SPP PF06550.11 CEH15267.1 - 0.0031 17.0 1.2 0.0051 16.3 1.2 1.4 1 0 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease COX6B PF02297.17 CEH15268.1 - 4.3e-23 81.3 1.3 8.2e-23 80.4 1.3 1.4 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb COX17 PF05051.13 CEH15268.1 - 0.034 14.5 0.2 11 6.5 0.2 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CHD5 PF04420.14 CEH15269.1 - 2.1e-36 125.2 0.2 2.1e-36 125.2 0.2 1.6 2 0 0 2 2 2 1 CHD5-like protein DUF2749 PF10907.8 CEH15269.1 - 0.36 11.0 2.6 0.42 10.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) Wtap PF17098.5 CEH15270.1 - 0.00044 20.2 0.3 0.00085 19.3 0.3 1.4 1 0 0 1 1 1 1 WTAP/Mum2p family UPF0172 PF03665.13 CEH15273.1 - 0.12 12.4 0.2 0.61 10.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) MDM10 PF12519.8 CEH15277.1 - 1e-87 295.0 0.2 1.6e-87 294.3 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 CEH15277.1 - 0.0044 16.5 0.0 0.29 10.6 0.0 2.5 3 0 0 3 3 3 2 Eukaryotic porin MFS_1 PF07690.16 CEH15278.1 - 5.3e-30 104.5 28.6 5.3e-30 104.5 28.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH15278.1 - 1.3e-08 34.1 10.2 5.8e-08 32.0 10.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CEH15278.1 - 2.5e-05 22.9 0.7 4.8e-05 22.0 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Kinesin PF00225.23 CEH15279.1 - 1e-110 369.8 0.0 1.7e-110 369.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEH15279.1 - 6.5e-24 84.6 0.0 7.9e-23 81.0 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding PAP_central PF04928.17 CEH15279.1 - 0.0085 15.1 1.1 0.015 14.3 1.1 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain GPS2_interact PF15784.5 CEH15279.1 - 0.19 12.2 4.4 0.55 10.7 4.4 1.8 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF648 PF04890.13 CEH15279.1 - 0.23 11.2 0.5 0.4 10.4 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF648) COG5 PF10392.9 CEH15279.1 - 1.2 9.3 7.2 2.6 8.2 7.2 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Wtap PF17098.5 CEH15279.1 - 1.4 8.8 11.9 0.14 12.1 6.1 2.1 2 0 0 2 2 2 0 WTAP/Mum2p family UPF0242 PF06785.11 CEH15279.1 - 1.6 8.8 9.6 0.099 12.7 2.8 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TFB6 PF17110.5 CEH15280.1 - 1.3e-06 28.2 10.5 4e-06 26.7 3.5 3.0 3 1 0 3 3 3 2 Subunit 11 of the general transcription factor TFIIH BUD22 PF09073.10 CEH15280.1 - 0.11 11.8 10.5 0.16 11.3 10.5 1.2 1 0 0 1 1 1 0 BUD22 VMA21 PF09446.10 CEH15281.1 - 1.1e-09 38.3 12.8 2.3e-09 37.2 12.8 1.5 1 1 0 1 1 1 1 VMA21-like domain Antimicrobial22 PF16047.5 CEH15283.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide ECH_1 PF00378.20 CEH15284.1 - 2.3e-22 79.6 0.1 4.2e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 CEH15284.1 - 0.011 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain ECH_1 PF00378.20 CEH15285.1 - 9.6e-35 120.1 0.4 4.3e-30 104.8 0.4 3.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEH15285.1 - 3.3e-26 92.6 0.1 4.6e-25 88.8 0.1 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UPF0160 PF03690.13 CEH15287.1 - 2.6e-123 411.7 0.0 2.9e-123 411.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF4841 PF16129.5 CEH15287.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) HCO3_cotransp PF00955.21 CEH15288.1 - 5.3e-51 174.0 11.6 5.8e-27 94.7 5.6 4.4 2 2 2 4 4 4 2 HCO3- transporter family OAD_gamma PF04277.13 CEH15289.1 - 0.14 12.7 4.7 0.29 11.7 2.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Plasmodium_Vir PF05795.11 CEH15289.1 - 2.6 7.4 4.0 3.9 6.8 4.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SurA_N_3 PF13624.6 CEH15289.1 - 5.7 6.7 14.9 12 5.7 14.9 1.4 1 0 0 1 1 1 0 SurA N-terminal domain X PF00739.19 CEH15289.1 - 7 6.8 12.7 0.28 11.3 0.5 2.7 2 1 0 2 2 2 0 Trans-activation protein X DUF3391 PF11871.8 CEH15289.1 - 9.2 6.8 12.0 18 5.9 7.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Complex1_LYR PF05347.15 CEH15290.1 - 3.7e-09 36.5 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CEH15290.1 - 0.00026 21.7 0.0 0.00031 21.4 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Hist_deacetyl PF00850.19 CEH15291.1 - 5.6e-83 278.9 0.0 8.2e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 CEH15291.1 - 5.6e-31 107.6 0.0 9.2e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain DUF202 PF02656.15 CEH15293.1 - 6.9 7.2 11.9 1.1 9.7 2.5 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF202) Sua5_yciO_yrdC PF01300.18 CEH15295.1 - 9.7e-51 171.8 0.0 9.2e-46 155.6 0.0 2.2 1 1 1 2 2 2 2 Telomere recombination SUA5 PF03481.13 CEH15295.1 - 7.8e-10 39.4 0.0 1.3e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF3842 PF12953.7 CEH15295.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) LGT PF01790.18 CEH15297.1 - 0.0025 17.1 0.5 0.0045 16.2 0.5 1.4 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase AA_permease PF00324.21 CEH15298.1 - 1e-101 340.9 33.2 1.2e-101 340.7 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEH15298.1 - 1.9e-29 102.8 38.1 2.2e-29 102.5 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF648 PF04890.13 CEH15298.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF648) Arm PF00514.23 CEH15299.1 - 1.3e-15 56.8 24.1 0.0013 18.7 0.1 7.9 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CEH15299.1 - 0.00053 20.0 23.3 0.37 11.2 0.0 8.5 9 0 0 9 9 9 2 HEAT repeat M11L PF11099.8 CEH15299.1 - 0.0037 17.5 1.0 0.022 15.0 0.0 2.6 3 0 0 3 3 3 1 Apoptosis regulator M11L like DUF4042 PF13251.6 CEH15299.1 - 0.044 13.5 1.1 0.078 12.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) DUF3361 PF11841.8 CEH15299.1 - 0.068 13.1 0.1 1.4 8.8 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3361) Phage_holin_3_1 PF05106.12 CEH15299.1 - 0.13 12.7 0.7 4.4 7.8 0.0 3.2 4 0 0 4 4 4 0 Phage holin family (Lysis protein S) HEAT_2 PF13646.6 CEH15299.1 - 0.19 12.1 26.3 1.1 9.7 3.0 7.2 4 3 2 6 6 6 0 HEAT repeats ELL PF10390.9 CEH15300.1 - 0.0018 17.8 0.5 0.0018 17.8 0.5 3.2 3 1 0 3 3 3 2 RNA polymerase II elongation factor ELL BrnA_antitoxin PF14384.6 CEH15300.1 - 0.31 11.5 0.0 0.31 11.5 0.0 3.6 4 0 0 4 4 4 0 BrnA antitoxin of type II toxin-antitoxin system YlqD PF11068.8 CEH15301.1 - 0.14 12.5 1.8 0.2 12.1 1.8 1.2 1 0 0 1 1 1 0 YlqD protein ubiquitin PF00240.23 CEH15302.1 - 3.9e-18 64.9 0.2 6e-18 64.4 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEH15302.1 - 5e-09 35.9 0.7 8.4e-09 35.1 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CEH15302.1 - 3.7e-06 27.4 0.0 6.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEH15302.1 - 0.00021 21.4 0.0 0.00036 20.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 CEH15302.1 - 0.0041 17.0 0.1 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_4 PF18036.1 CEH15302.1 - 0.032 14.3 0.5 0.31 11.1 0.2 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain FAM199X PF15814.5 CEH15302.1 - 0.04 13.0 1.9 0.058 12.5 1.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X Ubiquitin_2 PF14560.6 CEH15302.1 - 0.14 12.6 0.3 0.41 11.1 0.3 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 CEH15302.1 - 0.17 11.9 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain GerD PF17898.1 CEH15302.1 - 0.24 11.3 1.2 0.5 10.3 1.2 1.5 1 0 0 1 1 1 0 Spore germination GerD central core domain G_glu_transpept PF01019.21 CEH15303.1 - 1.3e-50 172.7 0.0 3.6e-44 151.4 0.0 2.1 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase RL10P_insert PF17777.1 CEH15305.1 - 8.7e-23 80.1 0.0 1.3e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CEH15305.1 - 7.8e-15 54.8 0.0 1.2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 GP67 PF17634.2 CEH15305.1 - 0.03 14.7 8.4 1.1 9.7 7.6 2.4 2 0 0 2 2 2 0 Gene product 67 GCIP PF13324.6 CEH15305.1 - 0.17 11.4 0.5 0.25 10.9 0.5 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 CEH15305.1 - 0.84 10.1 7.9 1.9 8.9 7.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3425 PF11905.8 CEH15307.1 - 1.1e-17 64.2 1.5 2.5e-17 63.0 0.3 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CEH15307.1 - 0.22 11.7 9.1 0.44 10.7 9.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 CEH15307.1 - 0.36 11.0 12.0 0.69 10.0 12.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper ANAPC_CDC26 PF10471.9 CEH15307.1 - 0.56 11.1 7.3 2.6 8.9 7.3 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 DUF3808 PF10300.9 CEH15310.1 - 1.2e-84 284.7 0.1 2.6e-84 283.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 CEH15310.1 - 0.0078 16.2 8.9 0.29 11.4 0.3 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 CEH15310.1 - 0.046 14.4 2.1 0.095 13.4 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEH15310.1 - 0.067 13.9 0.0 48 4.9 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ubiquitin PF00240.23 CEH15310.1 - 0.12 12.1 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family ANAPC3 PF12895.7 CEH15310.1 - 1.4 9.2 5.5 2.8 8.2 1.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5466 PF17554.2 CEH15310.1 - 3 8.1 6.8 0.26 11.5 0.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5466) PBP_sp32 PF07222.12 CEH15310.1 - 6.4 6.1 6.5 14 5.1 6.5 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Lyase_aromatic PF00221.19 CEH15311.1 - 3.7e-75 253.4 3.1 3.2e-57 194.2 1.8 2.2 2 0 0 2 2 2 2 Aromatic amino acid lyase TetR_C_31 PF17940.1 CEH15311.1 - 0.067 13.4 2.3 3.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Hemerythrin PF01814.23 CEH15311.1 - 0.25 11.9 3.3 7.6 7.2 0.1 2.8 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Pkinase PF00069.25 CEH15313.1 - 1.6e-57 194.9 0.0 1.1e-37 129.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15313.1 - 2.1e-24 86.2 0.0 5.4e-19 68.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 CEH15313.1 - 4.2e-10 39.8 0.0 9.2e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 CEH15313.1 - 8.9e-08 31.8 0.2 0.00011 21.7 0.0 2.6 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 CEH15313.1 - 0.00013 22.0 0.0 0.0012 18.8 0.0 2.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family PAS_9 PF13426.7 CEH15313.1 - 0.0016 18.6 0.0 0.0052 17.0 0.0 1.8 2 0 0 2 2 1 1 PAS domain FTA2 PF13095.6 CEH15313.1 - 0.013 15.2 0.0 6.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CEH15313.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 CEH15313.1 - 0.048 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEH15313.1 - 0.13 11.0 0.0 0.31 9.8 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 CEH15313.1 - 0.23 10.4 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_S18 PF01084.20 CEH15314.1 - 1.1e-15 57.5 0.2 2.8e-15 56.3 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 Ribosomal_L29e PF01779.17 CEH15315.1 - 5.8e-21 74.5 10.8 8.4e-21 74.0 10.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family DUF4505 PF14956.6 CEH15316.1 - 0.018 14.8 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) TAP_C PF03943.13 CEH15317.1 - 3.6e-14 52.1 0.9 5.8e-14 51.5 0.2 1.8 2 0 0 2 2 2 1 TAP C-terminal domain LRR_9 PF14580.6 CEH15317.1 - 1.2e-05 24.8 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CEH15317.1 - 0.019 15.4 1.3 0.2 12.1 0.4 2.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEH15317.1 - 0.16 11.8 0.1 0.51 10.1 0.1 1.8 1 0 0 1 1 1 0 Leucine rich repeat HK PF02110.15 CEH15318.1 - 4.9e-63 212.8 7.1 1.7e-62 211.0 2.4 2.4 2 1 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 CEH15318.1 - 2.2e-45 154.2 0.1 3.6e-45 153.5 0.1 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 CEH15318.1 - 0.00021 20.8 0.1 0.00048 19.6 0.1 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF1935 PF09149.10 CEH15320.1 - 0.066 13.6 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Tim17 PF02466.19 CEH15320.1 - 1.9 8.9 6.6 19 5.7 6.6 2.3 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family LSM_int_assoc PF16605.5 CEH15321.1 - 0.075 13.2 0.3 0.2 11.8 0.3 1.7 1 0 0 1 1 1 0 LSM-interacting associated unstructured Glt_symporter PF03616.14 CEH15321.1 - 0.17 10.5 0.0 0.35 9.5 0.0 1.4 1 0 0 1 1 1 0 Sodium/glutamate symporter MAGE PF01454.19 CEH15322.1 - 1.8e-45 155.3 0.0 4.4e-45 154.0 0.0 1.7 1 0 0 1 1 1 1 MAGE family MarR PF01047.22 CEH15322.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 MarR family DUF2890 PF11081.8 CEH15323.1 - 0.97 9.5 2.9 1.3 9.1 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CoaE PF01121.20 CEH15324.1 - 1.6e-51 174.6 0.0 2.2e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CEH15324.1 - 0.0036 17.9 0.0 0.016 15.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Cation_ATPase_N PF00690.26 CEH15324.1 - 0.02 14.6 0.0 0.065 12.9 0.0 1.9 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus AAA_33 PF13671.6 CEH15324.1 - 0.05 13.8 1.1 0.095 12.9 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.6 CEH15324.1 - 0.056 13.7 0.0 0.093 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CEH15324.1 - 0.092 13.2 0.0 0.23 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CEH15324.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain FA_desaturase PF00487.24 CEH15326.1 - 7.4e-06 26.0 1.2 7.2e-05 22.8 1.3 2.0 2 0 0 2 2 2 1 Fatty acid desaturase Pkinase PF00069.25 CEH15327.1 - 1.7e-73 247.2 0.0 3e-73 246.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15327.1 - 2.9e-35 121.8 0.0 5.2e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH15327.1 - 1.3e-05 24.7 2.5 0.68 9.2 0.0 3.7 4 0 0 4 4 4 3 Kinase-like Pkinase_fungal PF17667.1 CEH15327.1 - 0.0054 15.5 5.1 0.029 13.1 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEH15327.1 - 0.015 15.3 5.1 0.62 9.9 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Paf1 PF03985.13 CEH15327.1 - 2.3 7.1 18.5 3.6 6.5 15.0 2.1 2 0 0 2 2 2 0 Paf1 Ima1_N PF09779.9 CEH15327.1 - 3.7 8.4 9.4 5.6 7.8 0.2 2.5 2 0 0 2 2 2 0 Ima1 N-terminal domain Connexin PF00029.19 CEH15327.1 - 7.4 6.2 5.2 19 4.9 5.2 1.6 1 0 0 1 1 1 0 Connexin DHDPS PF00701.22 CEH15328.1 - 1e-39 136.0 0.0 1.2e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SelB-wing_1 PF09105.10 CEH15328.1 - 0.34 10.9 2.0 25 4.9 0.3 2.5 2 0 0 2 2 2 0 Elongation factor SelB, winged helix HORMA PF02301.18 CEH15330.1 - 1.8e-27 96.3 0.0 2.1e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 CEH15330.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial HORMA domain 2 CN_hydrolase PF00795.22 CEH15331.1 - 1.6e-48 165.4 0.0 2e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_1 PF00076.22 CEH15331.1 - 7.4e-19 67.3 0.0 1.2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEH15331.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ICMT PF04140.14 CEH15332.1 - 1e-26 93.2 0.5 3.2e-26 91.6 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CEH15332.1 - 1.5e-09 38.2 3.1 1.9e-09 37.9 0.3 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 CEH15332.1 - 0.0065 16.0 3.1 0.0092 15.5 2.4 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) NnrU PF07298.11 CEH15332.1 - 0.0075 15.8 11.0 0.025 14.1 11.1 1.8 1 1 1 2 2 2 1 NnrU protein ABC_membrane PF00664.23 CEH15333.1 - 1.2e-77 261.3 21.7 2e-40 139.2 1.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEH15333.1 - 6.2e-50 169.3 0.1 1.1e-30 107.0 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEH15333.1 - 5.7e-08 32.5 0.0 0.0026 17.3 0.2 3.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEH15333.1 - 0.00024 21.5 7.6 0.012 16.0 0.5 3.4 3 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 CEH15333.1 - 0.00088 19.3 0.3 0.25 11.4 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_ATPase PF09818.9 CEH15333.1 - 0.0016 17.3 0.2 0.0037 16.1 0.2 1.5 1 0 0 1 1 1 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 CEH15333.1 - 0.014 15.3 0.0 8.8 6.2 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 CEH15333.1 - 0.033 14.3 0.6 3 7.9 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 CEH15333.1 - 0.078 12.7 0.8 6.1 6.7 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 CEH15333.1 - 0.1 12.6 3.3 2.3 8.2 0.0 2.8 3 0 0 3 3 3 0 Dynamin family AAA_21 PF13304.6 CEH15333.1 - 0.17 11.7 0.2 24 4.6 0.0 2.6 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system GMC_oxred_N PF00732.19 CEH15334.1 - 5e-42 144.3 0.8 6.4e-42 143.9 0.2 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEH15334.1 - 1.7e-23 83.8 0.6 1.7e-23 83.8 0.6 2.4 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CEH15334.1 - 1.2e-07 31.2 2.2 1.9e-05 23.9 0.9 2.5 3 0 0 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.19 CEH15334.1 - 1.1e-05 24.8 0.3 3.6e-05 23.2 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CEH15334.1 - 5.6e-05 22.5 1.4 0.00018 20.9 1.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEH15334.1 - 6.4e-05 22.7 2.8 0.039 13.5 1.5 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEH15334.1 - 8.5e-05 22.7 0.8 0.00029 21.0 0.8 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CEH15334.1 - 0.00086 18.6 0.4 0.0021 17.3 0.4 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CEH15334.1 - 0.0017 17.1 0.6 0.011 14.4 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CEH15334.1 - 0.005 16.2 1.5 0.0084 15.5 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 CEH15334.1 - 0.14 11.2 0.2 0.23 10.5 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AA_permease PF00324.21 CEH15335.1 - 1.9e-123 412.6 23.2 2.4e-123 412.3 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEH15335.1 - 3.2e-36 125.1 26.0 4.2e-36 124.7 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease Nop16 PF09420.10 CEH15336.1 - 2.9e-50 171.2 3.1 4.7e-50 170.5 3.1 1.3 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 XAP5 PF04921.14 CEH15338.1 - 2.7e-82 276.4 15.5 6.5e-82 275.1 15.5 1.8 1 1 0 1 1 1 1 XAP5, circadian clock regulator DUF3512 PF12024.8 CEH15338.1 - 0.0024 17.4 1.2 0.95 8.9 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3512) RuBisCO_small PF00101.20 CEH15338.1 - 0.096 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain Arf PF00025.21 CEH15339.1 - 3.1e-36 124.4 0.0 8.9e-26 90.4 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CEH15339.1 - 4.8e-14 52.6 0.0 8e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEH15339.1 - 4.2e-13 49.2 0.0 1.5e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 CEH15339.1 - 2.8e-07 30.1 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEH15339.1 - 3e-06 26.8 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEH15339.1 - 6.2e-06 26.3 0.0 7.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CEH15339.1 - 1.2e-05 24.7 0.3 3.3e-05 23.2 0.1 1.7 1 1 1 2 2 2 1 G-protein alpha subunit Cupin_6 PF12852.7 CEH15339.1 - 0.044 13.5 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Cupin AAA_7 PF12775.7 CEH15339.1 - 0.053 13.0 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 CEH15339.1 - 0.093 12.8 0.1 2.3 8.3 0.3 2.1 1 1 1 2 2 2 0 Dynamin family ABC2_membrane PF01061.24 CEH15340.1 - 5.4e-33 114.2 21.9 5.4e-33 114.2 21.9 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CEH15340.1 - 3.3e-26 92.4 0.0 5.2e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 CEH15340.1 - 1.9e-09 37.1 23.5 3.5e-09 36.2 23.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 CEH15340.1 - 0.0014 18.3 0.1 0.0032 17.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEH15340.1 - 0.0045 16.9 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CEH15340.1 - 0.016 15.0 0.0 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system hEGF PF12661.7 CEH15340.1 - 0.018 15.6 17.9 0.88 10.3 0.2 4.3 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_2 PF07974.13 CEH15340.1 - 0.025 14.9 27.9 0.57 10.6 11.7 4.0 3 0 0 3 3 3 0 EGF-like domain AAA_22 PF13401.6 CEH15340.1 - 0.046 14.0 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CEH15340.1 - 0.081 13.5 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Imm_superinfect PF14373.6 CEH15340.1 - 0.14 12.1 3.7 0.47 10.4 3.7 1.9 1 0 0 1 1 1 0 Superinfection immunity protein AAA_25 PF13481.6 CEH15340.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CEH15340.1 - 0.21 11.7 0.0 0.45 10.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 CEH15340.1 - 0.26 11.7 0.0 0.45 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.24 CEH15340.1 - 0.7 10.1 32.1 0.37 11.0 0.8 4.0 4 0 0 4 4 3 0 Laminin EGF domain DUF295 PF03478.18 CEH15340.1 - 1.1 8.9 3.4 4.4 7.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF295) DUF2157 PF09925.9 CEH15340.1 - 9.1 6.1 11.1 3.5 7.4 6.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) IBN_N PF03810.19 CEH15341.1 - 9.5e-06 25.4 0.1 5e-05 23.1 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CEH15341.1 - 0.0073 16.7 1.9 0.028 14.8 0.1 2.9 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 CEH15341.1 - 0.0097 16.1 0.1 0.073 13.4 0.1 2.7 1 0 0 1 1 1 1 HEAT repeat Xpo1 PF08389.12 CEH15341.1 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Exportin 1-like protein DUF5076 PF16826.5 CEH15341.1 - 0.18 11.8 1.1 0.99 9.4 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5076) Peptidase_A22B PF04258.13 CEH15343.1 - 2e-78 263.8 3.9 7.1e-47 160.3 0.2 2.1 1 1 1 2 2 2 2 Signal peptide peptidase SPP PF06550.11 CEH15343.1 - 2.8e-07 30.3 2.0 3.3e-05 23.5 0.5 2.2 2 0 0 2 2 2 2 Signal-peptide peptidase, presenilin aspartyl protease COX7a PF02238.15 CEH15343.1 - 0.076 13.4 4.6 0.3 11.5 0.2 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII SMC_N PF02463.19 CEH15344.1 - 1.7e-65 220.6 2.3 2.4e-65 220.0 2.3 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CEH15344.1 - 6.6e-30 103.8 0.6 1.8e-29 102.4 0.1 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CEH15344.1 - 2e-18 67.3 15.1 4.1e-12 46.5 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 CEH15344.1 - 1.1e-16 62.0 16.5 1.1e-16 62.0 16.5 5.9 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 CEH15344.1 - 1.4e-16 61.2 4.6 8e-08 32.4 0.9 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEH15344.1 - 0.011 15.5 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 CEH15344.1 - 0.46 9.5 8.8 1.5 7.8 1.8 3.1 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 CEH15344.1 - 0.84 10.2 0.0 0.84 10.2 0.0 5.8 4 2 0 4 4 4 0 ABC transporter Peptidase_M55 PF04951.13 CEH15344.1 - 1.3 8.4 4.6 0.6 9.5 0.8 2.4 2 0 0 2 2 2 0 D-aminopeptidase AFG1_ATPase PF03969.16 CEH15346.1 - 7.8e-38 130.3 0.1 4.9e-35 121.1 0.0 2.7 2 1 0 2 2 2 2 AFG1-like ATPase LIME1 PF15332.6 CEH15346.1 - 0.0095 15.6 0.4 0.46 10.0 0.0 2.3 2 0 0 2 2 2 2 Lck-interacting transmembrane adapter 1 AAA_16 PF13191.6 CEH15346.1 - 0.054 13.9 0.1 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain EMP24_GP25L PF01105.24 CEH15347.1 - 3e-40 138.1 0.2 1.9e-28 99.6 0.0 2.1 2 0 0 2 2 2 2 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.18 CEH15348.1 - 1e-23 83.9 4.0 5.9e-17 62.1 0.4 2.4 1 1 1 2 2 2 2 RanBP1 domain WH1 PF00568.23 CEH15348.1 - 0.07 13.1 0.3 7.1 6.6 0.0 2.1 2 0 0 2 2 2 0 WH1 domain D5_N PF08706.11 CEH15348.1 - 0.22 11.8 2.5 0.37 11.0 2.5 1.4 1 1 0 1 1 1 0 D5 N terminal like Lactamase_B_6 PF16661.5 CEH15349.1 - 4.8e-43 146.8 0.0 6.6e-41 139.9 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CEH15349.1 - 2.7e-24 86.2 0.0 2.7e-24 86.2 0.0 2.9 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 CEH15349.1 - 9.1e-13 48.5 0.0 3.7e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 CEH15349.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Hist_deacetyl PF00850.19 CEH15350.1 - 3.6e-82 276.3 0.0 4.8e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain zf-MYND PF01753.18 CEH15351.1 - 0.054 13.6 4.2 0.098 12.8 4.2 1.4 1 0 0 1 1 1 0 MYND finger DivIC PF04977.15 CEH15351.1 - 0.21 11.4 0.0 0.52 10.1 0.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Atg14 PF10186.9 CEH15352.1 - 7.5e-09 35.1 0.0 1.4e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Sugar_tr PF00083.24 CEH15356.1 - 8e-96 321.6 9.1 9.4e-96 321.4 9.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH15356.1 - 6.1e-23 81.3 22.4 1.1e-22 80.4 22.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Herpes_UL56 PF04534.12 CEH15357.1 - 0.011 15.2 0.3 0.011 15.2 0.3 1.9 2 0 0 2 2 2 0 Herpesvirus UL56 protein Putative_PNPOx PF01243.20 CEH15357.1 - 0.079 13.2 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase PQQ PF01011.21 CEH15357.1 - 0.2 11.7 0.2 0.89 9.6 0.0 2.2 3 0 0 3 3 3 0 PQQ enzyme repeat RRN9 PF10680.9 CEH15357.1 - 1 9.7 5.4 0.89 9.9 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor DUF3391 PF11871.8 CEH15357.1 - 4.4 7.9 7.5 23 5.5 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Abhydrolase_3 PF07859.13 CEH15358.1 - 1.4e-34 119.9 0.0 3.5e-34 118.5 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CEH15358.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ribonuc_L-PSP PF01042.21 CEH15359.1 - 7.7e-30 103.4 2.4 7.6e-28 97.0 2.4 2.0 1 1 0 1 1 1 1 Endoribonuclease L-PSP adh_short_C2 PF13561.6 CEH15360.1 - 3.3e-61 206.8 0.3 4.4e-61 206.4 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH15360.1 - 3.3e-44 150.7 0.2 4.9e-44 150.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH15360.1 - 5.7e-12 45.9 0.0 9.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEH15360.1 - 0.013 14.9 0.1 0.074 12.5 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CEH15360.1 - 0.024 13.8 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein His_biosynth PF00977.21 CEH15360.1 - 0.078 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Vps55 PF04133.14 CEH15361.1 - 6.4e-41 139.0 8.2 7.2e-41 138.8 8.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Mito_morph_reg PF14972.6 CEH15361.1 - 0.025 14.2 0.5 0.041 13.5 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator CYYR1 PF10873.8 CEH15361.1 - 0.064 13.7 0.7 0.089 13.2 0.7 1.2 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF4231 PF14015.6 CEH15361.1 - 0.98 9.9 7.0 5.4 7.5 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Peptidase_C12 PF01088.21 CEH15363.1 - 4.6e-47 160.5 0.0 1.2e-46 159.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 AMP-binding PF00501.28 CEH15366.1 - 1.7e-73 247.6 0.0 3e-45 154.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CEH15366.1 - 1.6e-11 45.0 0.9 3.4e-10 40.8 0.2 3.1 3 2 0 3 3 3 1 AMP-binding enzyme C-terminal domain Zip PF02535.22 CEH15367.1 - 5.6e-64 216.5 8.4 6.4e-64 216.3 8.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter AbbA_antirepres PF14156.6 CEH15368.1 - 0.086 12.7 0.4 0.2 11.5 0.4 1.6 1 0 0 1 1 1 0 Antirepressor AbbA ADK PF00406.22 CEH15370.1 - 1.3e-27 96.8 0.0 3.9e-17 62.7 0.0 2.3 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CEH15370.1 - 2.3e-16 60.4 0.2 1.1e-14 55.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEH15370.1 - 1.4e-05 25.6 0.0 6.8e-05 23.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 CEH15370.1 - 0.099 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase MOZ_SAS PF01853.18 CEH15372.1 - 1.8e-81 272.1 0.0 2.4e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CEH15372.1 - 6e-24 83.4 2.4 1.2e-23 82.4 2.4 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CEH15372.1 - 0.003 17.9 0.0 0.0065 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEH15372.1 - 0.03 14.6 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-met PF12874.7 CEH15372.1 - 0.59 10.6 3.0 4 8.0 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CobN-Mg_chel PF02514.16 CEH15373.1 - 0.14 9.8 0.0 0.17 9.6 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase TMEM171 PF15471.6 CEH15375.1 - 1.2 8.0 3.3 2.7 6.9 3.3 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 Transferase PF02458.15 CEH15376.1 - 0.049 12.3 0.0 0.1 11.2 0.0 1.5 2 0 0 2 2 2 0 Transferase family CENP-P PF13096.6 CEH15377.1 - 0.026 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P End3 PF12761.7 CEH15377.1 - 0.058 13.6 4.4 0.099 12.8 4.4 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF1640 PF07798.11 CEH15377.1 - 0.37 10.8 4.7 0.7 9.9 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TFIIA PF03153.13 CEH15377.1 - 0.39 10.6 9.5 0.44 10.5 9.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CEH15377.1 - 0.84 9.1 13.7 0.26 10.8 10.8 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Uso1_p115_C PF04871.13 CEH15377.1 - 1.8 8.9 12.1 0.29 11.5 8.1 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region LPP PF04728.13 CEH15377.1 - 2.8 8.4 7.3 0.74 10.3 0.6 3.0 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Ndc1_Nup PF09531.10 CEH15377.1 - 4 6.0 11.7 6.5 5.3 11.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4407 PF14362.6 CEH15377.1 - 4.1 6.7 12.9 3.6 6.8 11.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5320 PF17253.2 CEH15377.1 - 4.9 8.3 5.2 2.6 9.2 1.7 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5320) RTA1 PF04479.13 CEH15378.1 - 3.9e-62 209.5 5.0 3.9e-62 209.5 5.0 1.3 2 0 0 2 2 2 1 RTA1 like protein ABC_cobalt PF09819.9 CEH15378.1 - 0.049 13.8 0.8 0.049 13.8 0.8 2.3 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component adh_short PF00106.25 CEH15379.1 - 1.3e-27 96.6 0.0 1.9e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH15379.1 - 1.2e-23 83.9 0.0 1.6e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CEH15379.1 - 9.8e-09 35.4 0.1 1.2e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CEH15379.1 - 3.4e-07 30.0 0.0 5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CEH15379.1 - 2.9e-06 27.3 0.4 3.8e-06 26.9 0.4 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 CEH15379.1 - 0.12 11.4 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CEH15379.1 - 0.14 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pep3_Vps18 PF05131.14 CEH15381.1 - 1.5e-48 164.4 0.0 2.8e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CEH15381.1 - 1.2e-09 38.2 0.0 9.1e-08 32.1 0.0 2.6 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CEH15381.1 - 1.1e-05 25.8 0.0 4.3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 CEH15381.1 - 0.00038 20.0 1.4 0.001 18.6 1.4 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CEH15381.1 - 0.00063 19.4 2.1 0.0014 18.3 2.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CEH15381.1 - 0.01 16.1 2.1 0.031 14.6 2.1 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CEH15381.1 - 0.014 15.3 2.6 0.033 14.0 2.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH15381.1 - 0.017 15.1 2.1 0.039 13.9 2.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF2175 PF09943.9 CEH15381.1 - 0.021 15.1 0.1 0.079 13.3 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-HC5HC2H_2 PF13832.6 CEH15381.1 - 0.13 12.4 0.2 0.34 11.1 0.2 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-C3H2C3 PF17122.5 CEH15381.1 - 0.18 11.8 0.8 0.48 10.5 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger zf-rbx1 PF12678.7 CEH15381.1 - 0.27 11.6 0.9 0.68 10.3 0.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEH15381.1 - 0.37 10.7 1.5 0.85 9.5 1.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEH15381.1 - 0.38 10.8 1.3 0.87 9.7 1.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Ribosomal_60s PF00428.19 CEH15381.1 - 1.3 9.7 28.6 0.13 12.8 3.4 4.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Zf_RING PF16744.5 CEH15381.1 - 1.3 9.2 4.6 0.34 11.0 0.7 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger TPR_2 PF07719.17 CEH15381.1 - 8.3 6.8 6.3 29 5.1 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat BCDHK_Adom3 PF10436.9 CEH15382.1 - 5.4e-42 143.4 0.2 8e-42 142.8 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CEH15382.1 - 0.078 13.5 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RcbX PF02341.15 CEH15382.1 - 0.08 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 RbcX protein Pyr_redox_2 PF07992.14 CEH15384.1 - 2.1e-51 174.9 0.1 2.9e-51 174.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEH15384.1 - 2.8e-09 37.4 3.0 0.01 16.4 0.0 3.8 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEH15384.1 - 0.0064 15.8 0.2 7.6 5.7 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_1_4 PF13692.6 CEH15384.1 - 0.031 14.7 0.0 0.085 13.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 GIDA PF01134.22 CEH15384.1 - 0.049 12.7 1.7 2.8 6.9 0.3 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A NCE101 PF11654.8 CEH15384.1 - 0.068 12.9 0.0 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Non-classical export protein 1 RVT_1 PF00078.27 CEH15386.1 - 3.6e-20 72.4 0.0 4.4e-19 68.9 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Replic_Relax PF13814.6 CEH15386.1 - 0.076 13.1 0.2 0.076 13.1 0.2 2.8 3 0 0 3 3 3 0 Replication-relaxation Glyco_hydro_11 PF00457.17 CEH15390.1 - 2e-37 128.5 1.4 5.9e-37 127.0 1.4 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 OTU PF02338.19 CEH15393.1 - 3e-23 82.7 0.0 4.5e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease ATP-synt_D PF01813.17 CEH15394.1 - 7.4e-58 195.6 7.5 2.3e-29 102.6 1.4 2.1 1 1 1 2 2 2 2 ATP synthase subunit D Lactamase_B_2 PF12706.7 CEH15397.1 - 0.00045 19.8 0.3 0.0018 17.8 0.3 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 CEH15397.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase Homeobox_KN PF05920.11 CEH15398.1 - 6.1e-18 64.4 0.1 1.9e-17 62.8 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CEH15398.1 - 4.3e-05 23.3 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain Eaf7 PF07904.13 CEH15400.1 - 1.7e-05 25.1 0.0 1.7e-05 25.1 0.0 3.8 2 2 0 2 2 2 1 Chromatin modification-related protein EAF7 gerPA PF10676.9 CEH15401.1 - 0.31 11.3 1.0 1e+02 3.3 0.0 3.8 3 0 0 3 3 3 0 Spore germination protein gerPA/gerPF Dioxygenase_C PF00775.21 CEH15402.1 - 2.6e-08 33.5 0.2 2.9e-07 30.1 0.2 2.2 1 1 0 1 1 1 1 Dioxygenase LRR_4 PF12799.7 CEH15404.1 - 0.0042 17.5 2.4 0.012 16.0 0.1 2.7 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEH15404.1 - 0.15 12.2 1.0 52 4.3 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich repeat Cgr1 PF03879.14 CEH15405.1 - 1.8e-19 70.1 21.6 2e-19 69.9 21.6 1.0 1 0 0 1 1 1 1 Cgr1 family DUF4558 PF15104.6 CEH15405.1 - 0.082 13.0 11.3 0.045 13.8 8.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4558) Yop-YscD_cpl PF16697.5 CEH15406.1 - 0.0018 18.6 0.1 0.0041 17.4 0.1 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 CEH15406.1 - 0.0018 18.6 0.0 0.0034 17.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain TPR_1 PF00515.28 CEH15407.1 - 4e-13 48.6 0.2 0.3 11.0 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEH15407.1 - 7.7e-07 28.8 43.9 0.023 14.8 0.0 12.5 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEH15407.1 - 0.0001 22.9 3.8 0.00043 20.9 0.7 11.4 13 3 1 14 14 12 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEH15407.1 - 0.0011 18.6 10.9 0.029 14.0 0.0 6.5 8 0 0 8 8 8 1 TPR repeat TPR_8 PF13181.6 CEH15407.1 - 0.0041 17.2 11.9 5.2 7.5 0.0 8.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEH15407.1 - 0.02 15.2 2.4 10 6.7 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEH15407.1 - 0.31 11.1 19.5 17 5.7 0.1 8.5 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEH15407.1 - 0.44 10.9 0.0 0.17 12.2 0.7 12.8 10 4 3 13 13 13 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEH15407.1 - 1.1 9.2 0.0 1.1 9.2 0.0 11.2 14 0 0 14 14 13 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEH15407.1 - 2.4 8.7 0.0 2.4 8.7 0.0 10.6 13 1 0 13 13 11 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEH15407.1 - 3.8 8.6 68.7 1.4 9.9 0.0 14.7 14 3 2 16 16 14 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEH15407.1 - 9 7.2 22.2 62 4.6 0.0 9.4 10 0 0 10 10 9 0 Tetratricopeptide repeat SH3_1 PF00018.28 CEH15408.1 - 7.9e-05 22.2 0.1 0.00022 20.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CEH15408.1 - 0.00075 19.3 0.2 0.0039 17.0 0.2 2.1 1 1 0 1 1 1 1 Variant SH3 domain Lactococcin_972 PF09683.10 CEH15408.1 - 0.68 10.5 0.0 0.68 10.5 0.0 3.2 4 0 0 4 4 4 0 Bacteriocin (Lactococcin_972) Abhydrolase_6 PF12697.7 CEH15409.1 - 1.3e-08 35.8 0.0 2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CEH15409.1 - 7.5e-05 22.4 0.0 0.00016 21.3 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 CEH15409.1 - 0.00016 21.4 0.0 0.0022 17.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH15409.1 - 0.00019 20.8 0.0 0.56 9.4 0.0 3.0 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CEH15409.1 - 0.004 16.6 0.0 0.083 12.4 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CEH15409.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M50B PF13398.6 CEH15410.1 - 3e-56 190.2 19.6 3.8e-56 189.9 19.6 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 CEH15410.1 - 0.19 11.0 0.4 0.43 9.8 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M50 Peptidase_M41 PF01434.18 CEH15410.1 - 0.21 11.4 0.1 0.31 10.9 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M41 ELFV_dehydrog PF00208.21 CEH15411.1 - 5.9e-56 189.9 0.0 8.2e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CEH15411.1 - 2.8e-25 88.1 0.0 7e-17 60.3 0.0 2.9 2 1 1 3 3 3 3 Bacterial NAD-glutamate dehydrogenase MT-A70 PF05063.14 CEH15412.1 - 1.2e-51 175.1 0.0 3.2e-34 118.3 0.0 2.2 2 0 0 2 2 2 2 MT-A70 WW PF00397.26 CEH15414.1 - 0.00014 21.9 0.2 0.00014 21.9 0.2 2.4 3 0 0 3 3 3 1 WW domain DUF4448 PF14610.6 CEH15415.1 - 0.041 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) FeoB_associated PF12669.7 CEH15415.1 - 0.27 11.7 0.3 0.49 10.8 0.3 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Macoilin PF09726.9 CEH15415.1 - 0.52 8.8 7.0 0.82 8.2 7.0 1.3 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_17 PF00332.18 CEH15416.1 - 0.022 14.3 1.5 2.4 7.7 0.2 2.2 1 1 1 2 2 2 0 Glycosyl hydrolases family 17 LPD23 PF18838.1 CEH15416.1 - 0.14 11.9 1.6 0.3 10.9 0.1 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 VTC PF09359.10 CEH15418.1 - 3.6e-99 331.6 0.0 7.4e-99 330.6 0.0 1.6 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 CEH15418.1 - 1.8e-19 70.9 25.1 7.7e-07 29.4 0.2 4.4 2 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 CEH15418.1 - 1.8e-13 50.7 0.3 4e-13 49.6 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Clc-like PF07062.12 CEH15418.1 - 0.62 9.5 1.8 1.1 8.6 1.8 1.3 1 0 0 1 1 1 0 Clc-like Mob1_phocein PF03637.17 CEH15419.1 - 1.2e-19 71.0 0.0 1.8e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family DUF913 PF06025.12 CEH15419.1 - 0.051 12.5 0.1 0.077 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sigma70_ner PF04546.13 CEH15419.1 - 0.091 12.6 4.8 0.18 11.7 4.8 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Vfa1 PF08432.10 CEH15419.1 - 6 7.1 7.7 20 5.5 0.2 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 CEH15419.1 - 6.4 4.9 10.9 8.5 4.5 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family HSP70 PF00012.20 CEH15420.1 - 2.6e-154 514.7 0.0 3.2e-154 514.4 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEH15420.1 - 1.1e-09 37.6 0.0 1.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein CsbD PF05532.12 CEH15422.1 - 0.023 14.6 3.5 0.11 12.4 0.2 2.5 2 1 0 2 2 2 0 CsbD-like YtxH PF12732.7 CEH15422.1 - 0.037 14.6 0.4 0.037 14.6 0.4 1.6 2 0 0 2 2 2 0 YtxH-like protein Mito_carr PF00153.27 CEH15423.1 - 5.2e-18 64.7 0.1 6.7e-06 25.9 0.0 5.3 5 0 0 5 5 5 5 Mitochondrial carrier protein START PF01852.19 CEH15425.1 - 9.4e-07 28.4 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 START domain Tannase PF07519.11 CEH15431.1 - 3.9e-77 260.2 1.1 2.4e-76 257.6 1.4 1.9 2 0 0 2 2 2 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 CEH15431.1 - 0.044 13.0 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Kinesin PF00225.23 CEH15432.1 - 1.5e-111 372.5 1.6 2.4e-111 371.9 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEH15432.1 - 1.3e-26 93.3 0.0 3.6e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding FPP PF05911.11 CEH15432.1 - 0.00011 20.7 4.0 0.00011 20.7 4.0 3.0 2 1 1 3 3 3 1 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 CEH15432.1 - 0.008 16.4 79.4 0.015 15.6 14.1 5.6 1 1 3 5 5 5 3 Autophagy protein 16 (ATG16) EMP24_GP25L PF01105.24 CEH15432.1 - 0.014 15.4 0.3 0.014 15.4 0.3 3.8 4 1 1 5 5 5 0 emp24/gp25L/p24 family/GOLD Sox_N PF12444.8 CEH15432.1 - 0.025 15.7 0.9 1.4 10.1 0.0 4.1 3 0 0 3 3 3 0 Sox developmental protein N terminal CinA_KH PF18146.1 CEH15432.1 - 0.78 9.9 3.2 7.2 6.9 0.7 3.8 2 1 1 3 3 3 0 Damage-inducible protein CinA KH domain GAS PF13851.6 CEH15432.1 - 0.97 8.7 73.4 0.31 10.4 7.6 6.0 3 1 3 6 6 6 0 Growth-arrest specific micro-tubule binding PI_PP_I PF18363.1 CEH15432.1 - 3.9 7.7 6.9 2.5 8.3 1.2 3.0 3 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain Filament PF00038.21 CEH15432.1 - 9.7 5.7 64.7 0.45 10.0 37.4 3.9 2 1 2 4 4 4 0 Intermediate filament protein Foie-gras_1 PF11817.8 CEH15433.1 - 1e-16 61.3 0.1 3.8e-16 59.5 0.1 2.0 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.12 CEH15433.1 - 3.7e-14 52.4 0.1 4.2e-07 29.1 0.5 2.2 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi TPR_6 PF13174.6 CEH15433.1 - 0.014 16.0 0.0 0.084 13.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ALGX PF16822.5 CEH15433.1 - 0.091 12.4 2.5 0.92 9.1 0.1 2.6 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX MT-A70 PF05063.14 CEH15434.1 - 1.2e-09 38.3 0.3 0.00085 19.3 0.0 3.9 2 1 1 3 3 3 2 MT-A70 PVL_ORF50 PF07768.11 CEH15434.1 - 0.0092 16.3 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 PVL ORF-50-like family SOG2 PF10428.9 CEH15435.1 - 1.7e-59 202.4 3.5 1.7e-59 202.4 3.5 5.3 3 2 1 5 5 5 2 RAM signalling pathway protein LRR_8 PF13855.6 CEH15435.1 - 9.4e-17 60.5 0.4 2.8e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CEH15435.1 - 8.7e-11 41.9 1.2 0.00047 20.5 0.0 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEH15435.1 - 0.00012 22.1 0.0 9.7 7.2 0.0 5.0 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 CEH15435.1 - 0.14 12.3 1.8 9.7 6.5 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 CEH15437.1 - 1.1e-11 44.8 11.8 0.00015 22.1 0.8 6.2 5 2 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEH15437.1 - 1.6e-10 40.8 0.8 8.1e-06 25.4 0.6 2.8 3 0 0 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 CEH15437.1 - 8.7e-09 35.0 17.2 8.7e-09 35.0 3.4 4.8 4 2 2 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 CEH15437.1 - 5.4e-08 32.3 10.3 0.41 11.4 0.1 6.9 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 CEH15437.1 - 0.21 11.8 16.4 18 5.7 0.1 7.1 8 0 0 8 8 8 0 Leucine Rich repeat TBCC PF07986.12 CEH15438.1 - 3.5e-14 52.6 0.1 6.1e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 CEH15438.1 - 0.15 12.6 2.8 0.17 12.3 1.0 2.0 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain GST_N_3 PF13417.6 CEH15439.1 - 0.00054 20.3 0.0 0.0019 18.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEH15439.1 - 0.058 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.20 CEH15440.1 - 4.5e-21 74.8 0.0 5.9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEH15440.1 - 0.001 19.5 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CEH15440.1 - 0.0048 17.1 0.0 0.026 14.7 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin ACOX PF01756.19 CEH15441.1 - 4.9e-26 91.4 0.1 9e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CEH15441.1 - 1e-16 61.6 0.4 1e-14 55.2 0.0 2.3 2 0 0 2 2 2 2 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CEH15441.1 - 2.7e-12 46.7 0.0 5.9e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Abhydro_lipase PF04083.16 CEH15442.1 - 1.9e-15 56.2 0.0 3.5e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CEH15442.1 - 9.3e-08 32.0 0.1 1.9e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH15442.1 - 0.0091 15.3 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SIR2 PF02146.17 CEH15443.1 - 5.8e-54 182.7 0.0 8.2e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family UQ_con PF00179.26 CEH15443.1 - 1.8e-35 121.6 0.0 1e-18 67.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme COX5B PF01215.19 CEH15443.1 - 0.1 12.3 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb OrfB_Zn_ribbon PF07282.11 CEH15443.1 - 0.17 11.8 2.7 0.13 12.2 0.8 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain SAICAR_synt PF01259.18 CEH15444.1 - 1.3e-91 306.7 0.0 1.9e-91 306.1 0.0 1.2 1 0 0 1 1 1 1 SAICAR synthetase SET PF00856.28 CEH15445.1 - 1.9e-11 44.6 0.0 1.6e-10 41.7 0.0 2.4 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 CEH15445.1 - 7.6e-11 42.8 0.7 2.2e-10 41.3 0.7 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Dus PF01207.17 CEH15446.1 - 7.3e-47 160.0 0.0 1.1e-46 159.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Pkinase PF00069.25 CEH15447.1 - 9e-66 221.9 0.0 1.2e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15447.1 - 8.4e-45 153.1 0.0 1.2e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH15447.1 - 5.8e-09 35.2 0.0 2e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CEH15447.1 - 1.2e-08 34.6 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEH15447.1 - 0.021 14.7 0.0 0.76 9.7 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CEH15447.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEH15447.1 - 0.7 8.8 2.6 1.2 8.0 0.0 2.4 2 1 0 2 2 2 0 Haspin like kinase domain Med10 PF09748.9 CEH15448.1 - 3.3e-22 78.7 0.0 4.5e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex EXS PF03124.14 CEH15449.1 - 2.1e-46 158.8 0.0 2.6e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 EXS family SOG2 PF10428.9 CEH15449.1 - 0.12 11.5 2.3 0.17 11.1 2.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NUFIP2 PF15293.6 CEH15449.1 - 7.4 5.3 11.0 11 4.8 11.0 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 EXS PF03124.14 CEH15450.1 - 3.2e-25 89.2 0.2 3.6e-25 89.0 0.2 1.1 1 0 0 1 1 1 1 EXS family Lactamase_B_2 PF12706.7 CEH15451.1 - 2.7e-20 72.8 0.0 1.4e-19 70.4 0.0 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEH15451.1 - 3.8e-07 30.1 0.0 0.00011 22.1 0.0 3.3 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CEH15451.1 - 0.004 17.2 0.0 0.023 14.7 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Herpes_UL17 PF04559.12 CEH15451.1 - 0.12 11.1 4.7 0.034 13.0 1.2 1.7 2 0 0 2 2 2 0 Herpesvirus UL17 protein Cytochrome-c551 PF10643.9 CEH15452.1 - 0.73 9.4 3.8 0.98 8.9 1.6 2.0 1 1 1 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 V-ATPase_C PF03223.15 CEH15454.1 - 2.3e-120 402.4 0.1 2.5e-120 402.3 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Peroxin-13_N PF04088.13 CEH15455.1 - 7e-50 169.1 0.3 1e-49 168.5 0.3 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 CEH15455.1 - 4e-12 45.6 0.0 7.1e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEH15455.1 - 1.1e-10 40.9 0.0 1.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEH15455.1 - 2.1e-10 40.3 0.1 3.4e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.14 CEH15455.1 - 0.038 13.6 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region TFIIS_M PF07500.14 CEH15456.1 - 1.2e-29 103.0 0.2 2.8e-29 101.8 0.0 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CEH15456.1 - 2.1e-17 62.6 7.2 3.4e-17 62.0 7.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CEH15456.1 - 1.8e-08 34.2 0.3 4.3e-08 33.0 0.3 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF1660 PF07874.11 CEH15456.1 - 0.064 13.8 0.6 0.1 13.1 0.1 1.6 1 1 0 1 1 1 0 Prophage protein (DUF1660) Prim-Pol PF09250.11 CEH15458.1 - 0.023 15.1 0.0 0.032 14.6 0.0 1.2 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal UTP15_C PF09384.10 CEH15459.1 - 2.1e-36 124.8 0.0 3.4e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CEH15459.1 - 4.1e-24 84.4 15.4 8.9e-08 32.7 0.1 7.8 7 1 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 CEH15459.1 - 0.00014 20.5 0.2 0.0025 16.4 0.1 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 CEH15459.1 - 0.00024 21.3 0.0 0.0058 16.9 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEH15459.1 - 0.00089 18.0 0.0 0.0019 16.9 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEH15459.1 - 0.032 13.2 0.2 4.5 6.1 0.0 3.2 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Fer2 PF00111.27 CEH15460.1 - 9.3e-12 44.7 0.2 1.6e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HIT PF01230.23 CEH15461.1 - 8.2e-25 87.4 0.3 1.2e-24 86.9 0.0 1.3 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 CEH15461.1 - 2.9e-14 53.5 0.0 4.2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CEH15461.1 - 0.0063 16.4 0.1 0.0093 15.8 0.1 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pkinase PF00069.25 CEH15462.1 - 5.6e-19 68.5 0.0 1.9e-14 53.7 0.0 3.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15462.1 - 4.9e-13 49.0 0.0 3.2e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase ANAPC15 PF15243.6 CEH15462.1 - 0.61 10.5 2.3 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 rRNA_processing PF08524.11 CEH15464.1 - 0.053 13.6 18.1 0.05 13.6 13.6 2.5 2 1 0 2 2 2 0 rRNA processing RRM_1 PF00076.22 CEH15466.1 - 2.7e-32 110.4 0.0 2.2e-19 69.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEH15466.1 - 8.9e-06 25.7 0.1 0.0083 16.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 CEH15466.1 - 0.048 13.9 0.2 0.093 13.0 0.2 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter PfkB PF00294.24 CEH15467.1 - 2.6e-09 36.8 0.0 4.8e-09 35.9 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase tRNA-synt_1b PF00579.25 CEH15468.1 - 2.1e-64 217.6 0.0 3.3e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) IMPa_helical PF18642.1 CEH15468.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Immunomodulating metalloprotease helical domain GCIP PF13324.6 CEH15469.1 - 8.3e-16 58.4 6.4 7.9e-15 55.2 1.7 3.4 2 1 0 2 2 2 2 Grap2 and cyclin-D-interacting Ribosomal_S21e PF01249.18 CEH15470.1 - 1.1e-36 124.8 0.0 1.2e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e ADH_zinc_N PF00107.26 CEH15471.1 - 2.1e-25 89.2 0.3 3.3e-25 88.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH15471.1 - 8.6e-12 44.9 0.1 7e-10 38.8 0.0 2.9 2 2 2 4 4 4 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CEH15471.1 - 3.2e-11 44.4 0.1 5.9e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CEH15471.1 - 0.0023 17.8 0.0 0.0054 16.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 CEH15471.1 - 0.018 15.3 0.1 0.028 14.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain GAD PF02938.14 CEH15471.1 - 0.059 13.6 0.3 17 5.8 0.1 3.0 2 0 0 2 2 2 0 GAD domain MIF4G PF02854.19 CEH15472.1 - 0.23 11.0 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain TP2 PF01254.18 CEH15474.1 - 1.7 9.3 11.6 1.9 9.1 11.6 1.0 1 0 0 1 1 1 0 Nuclear transition protein 2 adh_short PF00106.25 CEH15475.1 - 2.1e-22 79.5 0.6 2e-09 37.2 1.8 3.1 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEH15475.1 - 8.8e-14 51.6 2.7 7.4e-07 29.0 0.0 3.1 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH15475.1 - 8e-06 25.9 1.6 4.2e-05 23.5 1.6 1.9 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CEH15475.1 - 0.0084 16.0 1.1 0.015 15.2 1.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_S10 PF00450.22 CEH15477.1 - 1e-106 357.9 0.0 1.3e-106 357.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Snapin_Pallidin PF14712.6 CEH15478.1 - 0.15 12.5 1.3 0.31 11.5 0.7 1.8 2 0 0 2 2 2 0 Snapin/Pallidin FlxA PF14282.6 CEH15478.1 - 0.71 9.9 5.3 0.24 11.4 0.6 2.5 3 0 0 3 3 3 0 FlxA-like protein NDUF_B4 PF07225.12 CEH15479.1 - 1.4e-05 25.0 0.0 1.6e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DAP3 PF10236.9 CEH15480.1 - 2.3e-32 112.5 0.0 3.4e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CEH15480.1 - 2.8e-07 31.1 0.4 5.6e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 CEH15480.1 - 0.015 15.7 0.0 0.12 12.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Ric8 PF10165.9 CEH15481.1 - 1.2e-106 357.6 0.0 1.5e-106 357.3 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DUF1840 PF08895.11 CEH15481.1 - 0.58 10.5 2.7 7.3 7.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) GATA PF00320.27 CEH15482.1 - 1.3e-16 59.9 1.2 2.5e-16 59.0 1.2 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 CEH15482.1 - 8.2e-13 47.9 1.3 1.6e-12 47.0 1.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Herpes_LMP2 PF07415.11 CEH15482.1 - 0.96 8.2 2.5 2.5 6.8 2.5 1.6 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Mannosyl_trans3 PF11051.8 CEH15483.1 - 3.7e-41 141.3 0.0 5.8e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative BSD PF03909.17 CEH15484.1 - 2.1e-18 66.1 0.6 8.5e-15 54.5 0.2 2.7 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 CEH15484.1 - 1.8e-08 34.6 0.0 5e-08 33.2 0.0 1.8 2 1 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Mannosyl_trans3 PF11051.8 CEH15485.1 - 3.2e-20 72.6 0.0 6.8e-20 71.6 0.0 1.5 1 1 0 1 1 1 1 Mannosyltransferase putative EB PF01683.18 CEH15487.1 - 0.00028 21.1 55.5 0.2 12.0 10.9 4.9 1 1 3 4 4 4 4 EB module Dickkopf_N PF04706.12 CEH15487.1 - 0.0041 17.6 54.4 0.83 10.2 15.7 3.7 3 1 0 3 3 3 3 Dickkopf N-terminal cysteine-rich region UPF0506 PF11703.8 CEH15487.1 - 0.053 13.9 8.0 0.053 13.9 8.0 3.7 3 1 0 3 3 3 0 UPF0506 Nuc_sug_transp PF04142.15 CEH15488.1 - 4e-64 216.8 12.3 2.1e-43 148.7 0.9 2.5 1 1 1 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 CEH15488.1 - 0.0001 21.6 12.8 0.00021 20.6 12.8 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 CEH15488.1 - 0.00032 20.9 2.7 0.00032 20.9 2.7 3.4 3 1 1 4 4 4 1 EamA-like transporter family PUNUT PF16913.5 CEH15488.1 - 1.3 8.2 16.6 0.093 11.9 10.3 1.9 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport DUF4395 PF14340.6 CEH15488.1 - 1.5 9.2 10.5 0.47 10.8 1.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4395) DUF1129 PF06570.11 CEH15488.1 - 1.8 8.0 6.4 0.63 9.5 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) CRT-like PF08627.10 CEH15488.1 - 1.9 7.3 9.8 15 4.4 9.8 2.2 1 1 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like Stealth_CR2 PF11380.8 CEH15489.1 - 1.1e-12 48.1 0.1 1e-07 32.1 0.0 3.5 3 0 0 3 3 3 2 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 CEH15489.1 - 7.3e-05 22.6 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR1 PF17101.5 CEH15489.1 - 0.00026 20.7 0.1 0.00091 18.9 0.1 2.0 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 CEH15489.1 - 0.00026 20.8 0.1 0.00067 19.5 0.1 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 EF-hand_5 PF13202.6 CEH15489.1 - 0.065 12.7 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 EF hand Glycos_transf_1 PF00534.20 CEH15490.1 - 1.6e-26 92.9 0.0 4.1e-26 91.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEH15490.1 - 2.3e-12 47.5 0.2 2.2e-11 44.3 0.2 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CEH15490.1 - 5.1e-06 26.8 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CEH15490.1 - 5.1e-06 26.6 0.0 9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 GMC_oxred_C PF05199.13 CEH15493.1 - 1.4e-29 103.5 0.0 2e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CEH15493.1 - 1.7e-19 70.3 0.0 2.3e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Abhydrolase_3 PF07859.13 CEH15494.1 - 5.5e-11 42.7 0.5 1.2e-10 41.6 0.2 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEH15494.1 - 4.1e-07 29.7 0.0 0.0017 17.8 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family AidB_N PF18158.1 CEH15495.1 - 2.8e-17 63.1 0.0 7.3e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 CEH15495.1 - 7.8e-13 48.4 0.0 1.9e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CEH15495.1 - 4.2e-10 40.0 1.8 1.7e-08 34.8 0.1 3.2 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEH15495.1 - 0.0001 22.9 0.2 0.00041 21.0 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain ArAE_2_N PF10337.9 CEH15496.1 - 1.8e-33 116.3 0.0 1.8e-33 116.3 0.0 1.7 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CEH15496.1 - 2.2e-11 44.0 22.0 3.6e-11 43.3 17.2 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like MFAP1 PF06991.11 CEH15496.1 - 0.0056 16.6 1.0 0.012 15.5 1.0 1.5 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing SR-25 PF10500.9 CEH15496.1 - 0.021 14.4 2.8 0.035 13.7 2.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FHA PF00498.26 CEH15497.1 - 1.4e-05 25.3 0.1 4.1e-05 23.9 0.1 1.8 1 1 0 1 1 1 1 FHA domain ATP-synt_C PF00137.21 CEH15498.1 - 2.5e-33 114.2 35.5 1.6e-21 76.4 15.5 2.3 2 0 0 2 2 2 2 ATP synthase subunit C IncD PF17628.2 CEH15498.1 - 2.4 8.0 5.4 3.3 7.5 4.6 1.7 1 1 0 1 1 1 0 Inclusion membrane protein D DNA_methylase PF00145.17 CEH15499.1 - 2.5e-47 161.8 0.0 1.4e-46 159.4 0.0 1.9 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 CEH15499.1 - 0.043 13.4 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 CEH15499.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PAP2 PF01569.21 CEH15500.1 - 1.1e-16 60.8 5.3 1.1e-16 60.8 5.3 2.0 2 0 0 2 2 2 1 PAP2 superfamily DinB_2 PF12867.7 CEH15501.1 - 0.00018 22.0 1.1 0.00035 21.1 1.1 1.5 1 1 0 1 1 1 1 DinB superfamily DinB PF05163.12 CEH15501.1 - 0.0074 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 DinB family MDMPI_N PF11716.8 CEH15501.1 - 0.011 16.4 0.2 0.019 15.7 0.2 1.4 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Docking PF08990.11 CEH15501.1 - 0.045 13.4 0.2 0.074 12.7 0.2 1.4 1 0 0 1 1 1 0 Erythronolide synthase docking ABC_membrane PF00664.23 CEH15502.1 - 1.4e-111 372.5 21.8 1e-59 202.4 7.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEH15502.1 - 3.6e-70 234.8 0.1 1.7e-34 119.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEH15502.1 - 5.1e-14 52.2 0.0 1.9e-05 24.2 0.8 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CEH15502.1 - 2e-09 36.8 0.3 0.0022 16.9 0.0 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 CEH15502.1 - 8.6e-07 28.6 0.4 0.0032 17.2 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CEH15502.1 - 1.5e-06 28.7 5.1 0.0021 18.5 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CEH15502.1 - 5e-06 26.5 0.1 0.14 12.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CEH15502.1 - 6e-06 26.2 0.0 0.063 13.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 CEH15502.1 - 7.4e-06 25.4 0.0 0.013 14.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 CEH15502.1 - 2.6e-05 24.5 5.5 0.23 11.7 0.2 4.1 3 2 0 3 3 2 2 AAA domain AAA_30 PF13604.6 CEH15502.1 - 7.8e-05 22.5 1.7 0.57 9.9 0.3 3.8 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CEH15502.1 - 0.00036 20.5 0.0 0.29 11.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 CEH15502.1 - 0.0008 19.8 1.3 4.7 7.6 0.1 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 CEH15502.1 - 0.0014 18.8 0.4 1.9 8.6 0.0 2.9 3 0 0 3 3 2 2 Helicase HerA, central domain G-alpha PF00503.20 CEH15502.1 - 0.004 16.4 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_23 PF13476.6 CEH15502.1 - 0.0048 17.4 0.2 0.87 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEH15502.1 - 0.0056 16.3 0.8 0.25 10.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 CEH15502.1 - 0.0076 16.3 0.1 9.1 6.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CEH15502.1 - 0.016 15.5 0.4 3.8 7.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 CEH15502.1 - 0.027 14.0 0.0 5.5 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 CEH15502.1 - 0.035 14.3 0.1 2.8 8.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 CEH15502.1 - 0.069 13.4 9.2 1.5 9.1 0.6 3.9 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 CEH15502.1 - 0.079 12.7 0.1 7.9 6.2 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CEH15502.1 - 0.097 13.2 0.0 16 6.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CEH15502.1 - 0.11 12.9 1.5 31 5.0 0.0 3.8 4 0 0 4 4 3 0 AAA domain APS_kinase PF01583.20 CEH15502.1 - 0.12 12.3 0.2 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase Rad17 PF03215.15 CEH15502.1 - 0.14 12.1 0.2 2.4 8.0 0.2 2.5 2 1 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 CEH15502.1 - 0.19 11.4 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain FA_desaturase PF00487.24 CEH15502.1 - 9 6.0 9.0 1 9.2 0.7 3.2 3 1 0 3 3 3 0 Fatty acid desaturase Methyltr_RsmB-F PF01189.17 CEH15503.1 - 2.6e-11 43.5 0.0 9.4e-05 22.1 0.0 3.6 3 0 0 3 3 3 3 16S rRNA methyltransferase RsmB/F adh_short_C2 PF13561.6 CEH15506.1 - 2.2e-50 171.4 0.1 2.8e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH15506.1 - 2.3e-48 164.2 0.1 2.9e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH15506.1 - 2.2e-07 31.0 0.0 3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CEH15506.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Bac_A_amyl_C PF18612.1 CEH15506.1 - 0.018 14.8 0.0 0.056 13.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial Alpha amylase C-terminal domain NlpE_C PF17185.4 CEH15506.1 - 0.038 14.3 0.1 0.08 13.2 0.1 1.5 1 0 0 1 1 1 0 NlpE C-terminal OB domain Fib_alpha PF08702.10 CEH15508.1 - 5.5 7.2 14.1 2.4 8.3 0.0 4.4 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Mpp10 PF04006.12 CEH15509.1 - 0.18 10.2 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Mpp10 protein Methyltransf_25 PF13649.6 CEH15510.1 - 0.00028 21.5 0.1 0.00054 20.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PIG-P PF08510.12 CEH15511.1 - 0.84 9.6 4.6 0.2 11.6 0.6 2.0 2 0 0 2 2 2 0 PIG-P PPR_2 PF13041.6 CEH15512.1 - 4e-25 87.8 0.0 2.1e-08 34.2 0.0 7.7 7 1 1 8 8 8 3 PPR repeat family PPR PF01535.20 CEH15512.1 - 1.5e-16 59.4 0.6 0.031 14.5 0.0 9.5 11 0 0 11 11 11 4 PPR repeat PPR_3 PF13812.6 CEH15512.1 - 1.5e-15 57.0 0.0 7.9e-06 25.9 0.0 5.5 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.4 CEH15512.1 - 4.4e-10 39.3 0.9 4.5e-05 22.9 0.0 5.1 3 2 2 5 5 5 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CEH15512.1 - 1.4e-06 27.9 0.1 0.21 11.3 0.0 5.7 6 0 0 6 6 6 2 PPR repeat TPR_7 PF13176.6 CEH15512.1 - 0.049 13.7 0.1 7.8 6.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat OMPdecase PF00215.24 CEH15513.1 - 2.6e-71 239.8 0.2 3.9e-71 239.2 0.2 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family ChaC PF04752.12 CEH15513.1 - 1.8e-48 164.9 0.0 2.9e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein DUF1754 PF08555.10 CEH15514.1 - 8.2e-06 26.5 1.1 8.2e-06 26.5 1.1 2.0 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) FH2 PF02181.23 CEH15517.1 - 1.6e-69 234.8 2.1 1.6e-69 234.8 2.1 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CEH15517.1 - 1.5e-45 155.1 0.0 5.6e-45 153.2 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CEH15517.1 - 9.6e-38 129.8 0.8 2.8e-37 128.2 0.0 2.2 2 1 0 2 2 2 1 Diaphanous FH3 Domain CorA PF01544.18 CEH15517.1 - 7.1 5.9 7.6 1.3 8.3 0.4 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein KH_1 PF00013.29 CEH15518.1 - 3.8e-45 151.6 9.4 6.1e-17 61.2 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CEH15518.1 - 7.2e-16 57.8 5.1 3.3e-05 23.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CEH15518.1 - 9.8e-06 25.4 1.2 0.68 9.8 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CEH15518.1 - 0.016 15.3 7.1 0.77 9.9 0.1 3.6 3 1 0 3 3 3 0 NusA-like KH domain MOEP19 PF16005.5 CEH15518.1 - 0.11 12.5 0.0 8 6.5 0.0 2.8 3 0 0 3 3 3 0 KH-like RNA-binding domain MFS_1 PF07690.16 CEH15521.1 - 1.9e-32 112.6 39.5 1.9e-32 112.6 39.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CEH15521.1 - 1.4e-06 27.0 2.4 2.3e-06 26.4 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CEH15521.1 - 0.0028 16.0 3.5 0.0028 16.0 3.5 2.1 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M16 PF00675.20 CEH15522.1 - 2.7e-53 179.9 0.2 4.9e-53 179.1 0.2 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CEH15522.1 - 4.3e-39 134.4 0.0 9.1e-37 126.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain Nop53 PF07767.11 CEH15523.1 - 2.3e-55 188.6 20.5 2.6e-55 188.4 20.5 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) RICH PF05062.12 CEH15523.1 - 0.03 14.7 1.6 0.084 13.2 1.6 1.8 1 0 0 1 1 1 0 RICH domain PDZ_2 PF13180.6 CEH15523.1 - 0.12 12.7 0.3 0.26 11.6 0.3 1.5 1 0 0 1 1 1 0 PDZ domain tRNA-synt_2b PF00587.25 CEH15524.1 - 1.8e-37 129.1 0.0 3.2e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEH15524.1 - 2.4e-17 62.8 0.0 5.7e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 CEH15524.1 - 1.9e-14 53.4 0.0 4.1e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 CEH15524.1 - 1.4e-10 41.1 0.0 2.8e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Metallophos PF00149.28 CEH15525.1 - 4e-29 102.6 0.2 1.4e-28 100.8 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 CEH15525.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) APS_kinase PF01583.20 CEH15526.1 - 5.7e-69 231.0 0.0 6.8e-69 230.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 CEH15526.1 - 0.00023 21.7 0.0 0.00034 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEH15526.1 - 0.00046 20.4 0.0 0.00072 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CEH15526.1 - 0.0086 15.5 0.0 0.016 14.7 0.0 1.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 CLP1_P PF16575.5 CEH15526.1 - 0.023 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 CEH15526.1 - 0.024 13.9 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 CEH15526.1 - 0.026 14.2 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Myb_DNA-binding PF00249.31 CEH15528.1 - 7.3e-33 112.5 9.8 3.3e-12 46.4 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH15528.1 - 1.2e-27 96.0 2.1 7.7e-15 54.9 0.5 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 CEH15528.1 - 0.0021 18.2 2.2 0.79 9.9 0.2 4.0 3 2 0 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.8 CEH15528.1 - 0.0024 17.9 2.8 0.24 11.5 1.4 2.6 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 CEH15528.1 - 0.049 13.5 0.2 3.3 7.7 0.0 2.7 3 0 0 3 3 3 0 Myb DNA-binding like SLIDE PF09111.10 CEH15528.1 - 0.056 13.5 0.0 39 4.3 0.0 3.1 1 1 2 3 3 3 0 SLIDE MADF_DNA_bdg PF10545.9 CEH15528.1 - 0.076 13.3 7.3 2.5 8.5 0.9 3.0 2 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CEH15528.1 - 0.086 13.2 7.2 1.9 8.9 1.5 3.2 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain MFS_1 PF07690.16 CEH15531.1 - 1.1e-11 44.2 29.3 1.1e-11 44.2 29.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2019 PF09450.10 CEH15531.1 - 0.091 12.7 0.5 0.25 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) DUF2613 PF11021.8 CEH15531.1 - 1.2 9.3 4.7 5.8 7.1 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) DUF2207 PF09972.9 CEH15531.1 - 3.5 6.3 4.4 8.4 5.0 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) pXO2-34 PF17362.2 CEH15533.1 - 0.012 15.4 0.0 39 4.2 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function Lipase_3 PF01764.25 CEH15535.1 - 2.1e-23 82.7 0.0 2.8e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CEH15535.1 - 0.043 14.4 1.7 0.075 13.6 1.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH15535.1 - 0.053 12.8 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TFIIS_M PF07500.14 CEH15536.1 - 5.4e-13 49.4 0.9 1.8e-12 47.8 0.9 1.9 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 CEH15536.1 - 1.3e-09 38.1 0.0 3.7e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 CEH15536.1 - 2.2e-09 37.0 7.1 3.8e-09 36.3 7.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CEH15536.1 - 0.16 11.5 3.1 0.35 10.5 3.1 1.5 1 0 0 1 1 1 0 PHD-finger CRAL_TRIO PF00650.20 CEH15537.1 - 1.3e-32 112.8 0.0 2e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEH15537.1 - 6.2e-10 39.1 0.8 6.2e-10 39.1 0.8 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CEH15537.1 - 2.6e-09 37.4 0.0 4.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF5348 PF17295.2 CEH15538.1 - 0.28 11.1 1.0 7.4 6.6 0.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5348) S36_mt PF10937.8 CEH15541.1 - 1.9e-14 55.2 0.8 2.3e-14 54.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Porin_3 PF01459.22 CEH15542.1 - 6.1e-79 265.3 0.5 7e-79 265.1 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin ETC_C1_NDUFA4 PF04800.12 CEH15543.1 - 4.4e-35 119.8 0.5 6.2e-35 119.3 0.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Zn_clus PF00172.18 CEH15544.1 - 8.3e-06 25.8 7.7 8.3e-06 25.8 7.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 CEH15544.1 - 0.00078 19.8 0.0 0.00078 19.8 0.0 1.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEH15544.1 - 0.0095 16.7 0.0 0.04 14.8 0.0 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger DUF1610 PF07754.11 CEH15544.1 - 0.1 12.6 0.6 0.27 11.2 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) SET PF00856.28 CEH15546.1 - 1.6e-09 38.3 0.0 8.8e-09 36.0 0.0 2.3 2 1 0 2 2 2 1 SET domain HhH-GPD PF00730.25 CEH15547.1 - 5.8e-16 58.9 0.0 1.2e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CEH15547.1 - 2.4e-08 33.4 0.0 8.2e-08 31.7 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif Ank_4 PF13637.6 CEH15548.1 - 5.9e-21 74.6 0.6 8.8e-13 48.5 0.1 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEH15548.1 - 5.9e-19 68.4 0.0 4e-09 36.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 CEH15548.1 - 9.4e-16 57.5 0.0 4.9e-05 23.6 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CEH15548.1 - 1.2e-14 54.1 0.4 1.3e-06 28.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEH15548.1 - 4.7e-13 48.1 0.1 0.00093 19.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 CEH15548.1 - 1.6e-05 24.7 0.1 0.00054 19.8 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain BCOR PF15808.5 CEH15548.1 - 0.11 12.7 0.8 0.27 11.4 0.8 1.5 1 0 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region Metallophos_2 PF12850.7 CEH15549.1 - 0.0033 17.7 0.0 0.0053 17.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CEH15549.1 - 0.19 12.2 0.0 0.24 11.9 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase GAF PF01590.26 CEH15552.1 - 2.2e-08 34.8 0.0 7.2e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 CEH15552.1 - 3.7e-07 30.5 1.0 7.6e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 GAF domain ATG16 PF08614.11 CEH15552.1 - 0.64 10.2 3.2 14 5.9 0.4 3.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Abhydrolase_3 PF07859.13 CEH15553.1 - 5.2e-30 104.9 0.3 4.4e-14 52.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Glyco_hydro_20b PF02838.15 CEH15553.1 - 0.0037 18.1 0.1 0.0058 17.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF4202 PF13875.6 CEH15554.1 - 5.7e-56 189.4 0.1 1e-55 188.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Methyltransf_23 PF13489.6 CEH15554.1 - 4.9e-15 55.7 0.0 1.3e-14 54.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH15554.1 - 2.7e-12 47.3 0.0 9.5e-12 45.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH15554.1 - 7.7e-12 45.8 0.0 5.3e-11 43.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH15554.1 - 3e-09 37.4 0.0 9.2e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH15554.1 - 1.1e-06 28.5 0.0 2.4e-05 24.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CEH15554.1 - 0.00086 18.6 0.0 0.072 12.3 0.0 2.3 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family HMG_box PF00505.19 CEH15554.1 - 0.0036 17.7 1.5 0.01 16.2 0.0 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box MTS PF05175.14 CEH15554.1 - 0.0096 15.5 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CEH15554.1 - 0.012 14.9 0.0 0.076 12.3 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 CEH15554.1 - 0.058 14.4 0.0 0.82 10.7 0.0 2.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 CEH15554.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase R3H PF01424.22 CEH15556.1 - 3.1e-11 43.1 0.0 1e-10 41.5 0.0 2.0 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 CEH15556.1 - 1.5e-06 28.0 1.4 1.5e-06 28.0 1.4 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CEH15556.1 - 0.0063 16.6 1.8 0.016 15.3 0.7 2.5 2 0 0 2 2 2 1 G-patch domain Fcf1 PF04900.12 CEH15558.1 - 9.9e-37 125.3 1.1 1.5e-36 124.7 1.1 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CEH15558.1 - 9e-11 42.1 0.0 1.4e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 PIN like domain NDUF_B7 PF05676.13 CEH15559.1 - 2.6e-28 97.5 2.8 3.4e-28 97.2 2.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Myb_DNA-binding PF00249.31 CEH15561.1 - 0.055 13.7 0.4 0.16 12.2 0.4 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain DUF3012 PF11216.8 CEH15561.1 - 0.15 12.1 1.4 0.25 11.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) NAD_binding_1 PF00175.21 CEH15563.1 - 1.1e-07 32.5 0.0 7.4e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CEH15563.1 - 0.00068 19.8 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DnaJ PF00226.31 CEH15564.1 - 4.3e-19 68.4 0.1 4.3e-19 68.4 0.1 2.6 3 0 0 3 3 3 1 DnaJ domain DUF2332 PF10094.9 CEH15564.1 - 0.033 13.7 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) RNA_pol_Rpb5_C PF01191.19 CEH15564.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain MIF4G_like_2 PF09090.11 CEH15565.1 - 3e-66 223.6 0.1 8.9e-66 222.1 0.0 1.9 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.11 CEH15565.1 - 7.5e-64 215.0 0.0 1.8e-63 213.8 0.0 1.6 2 0 0 2 2 2 1 MIF4G like BAF1_ABF1 PF04684.13 CEH15565.1 - 0.0033 16.5 2.9 0.0033 16.5 2.9 1.7 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor UbiA PF01040.18 CEH15566.1 - 4.4e-46 157.2 7.5 5e-46 157.0 7.5 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3404 PF11884.8 CEH15568.1 - 0.05 12.8 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) Dicty_REP PF05086.12 CEH15570.1 - 3.1 5.7 4.5 4.1 5.3 4.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.8 CEH15570.1 - 4.7 6.3 10.1 8.4 5.5 10.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NOG1_N PF17835.1 CEH15571.1 - 6.4e-46 156.2 0.3 6.4e-46 156.2 0.3 2.3 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 CEH15571.1 - 3.9e-27 93.8 0.1 7.9e-27 92.8 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CEH15571.1 - 3.1e-18 65.9 0.0 1e-17 64.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH15571.1 - 1.1e-08 34.8 0.0 2.4e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B NOGCT PF08155.11 CEH15571.1 - 4.4e-06 26.6 0.2 4.4e-06 26.6 0.2 2.3 1 1 1 2 2 2 1 NOGCT (NUC087) domain Dynamin_N PF00350.23 CEH15571.1 - 0.0012 19.0 2.7 1.9 8.5 0.0 3.6 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 CEH15571.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 CEH15571.1 - 0.023 14.6 0.0 0.92 9.4 0.0 3.1 2 1 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CEH15571.1 - 0.08 13.2 0.0 0.56 10.4 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CEH15571.1 - 0.11 12.9 0.1 0.48 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NFACT-R_1 PF05670.13 CEH15572.1 - 1.1e-39 135.4 0.0 2.3e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF4407 PF14362.6 CEH15572.1 - 6.1 6.1 15.2 6.8 5.9 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myb_DNA-bind_6 PF13921.6 CEH15573.1 - 0.01 16.1 0.0 0.035 14.3 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Leuk-A4-hydro_C PF09127.11 CEH15573.1 - 0.024 14.7 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Myb_DNA-binding PF00249.31 CEH15573.1 - 0.096 12.9 0.2 0.67 10.2 0.2 2.3 1 1 0 1 1 1 0 Myb-like DNA-binding domain BSP_II PF05432.11 CEH15573.1 - 0.18 11.5 13.0 0.26 11.0 13.0 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SWIRM-assoc_2 PF16496.5 CEH15573.1 - 0.24 10.2 15.3 0.35 9.7 15.3 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CDC45 PF02724.14 CEH15573.1 - 2.1 6.5 9.7 2.4 6.4 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CCSAP PF15748.5 CEH15573.1 - 2.3 8.3 18.3 3.6 7.7 18.3 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 CEH15573.1 - 7.9 5.1 8.8 8.8 5.0 8.8 1.2 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CEH15573.1 - 9 5.6 9.2 12 5.2 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PTPlike_phytase PF14566.6 CEH15574.1 - 5.7e-124 409.8 0.0 9e-43 146.1 0.0 3.3 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 CEH15574.1 - 0.00041 20.2 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PrpF PF04303.13 CEH15576.1 - 6.2e-51 173.5 0.2 8.1e-35 120.5 0.0 3.1 3 0 0 3 3 3 3 PrpF protein DUF3263 PF11662.8 CEH15576.1 - 0.025 14.4 0.1 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) TetR_C_36 PF18598.1 CEH15577.1 - 0.017 15.1 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Glyco_hydro_63 PF03200.16 CEH15579.1 - 3e-160 534.2 0.0 4.3e-159 530.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CEH15579.1 - 5.3e-39 134.6 0.0 9.8e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 CEH15579.1 - 2.2e-09 36.7 0.3 2.9e-09 36.3 0.3 1.2 1 0 0 1 1 1 1 Trehalase GST_N_3 PF13417.6 CEH15580.1 - 1e-15 57.9 0.0 1.8e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEH15580.1 - 3.8e-14 52.8 0.0 1.2e-13 51.1 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEH15580.1 - 9.4e-09 35.5 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CEH15580.1 - 7.8e-07 29.2 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEH15580.1 - 2.2e-06 27.8 0.0 4.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEH15580.1 - 9.5e-06 25.6 0.1 3.4e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GTA_holin_3TM PF11351.8 CEH15580.1 - 0.11 13.0 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release GST_N_4 PF17172.4 CEH15580.1 - 0.19 12.5 0.0 0.8 10.5 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain SeleniumBinding PF11524.8 CEH15580.1 - 0.21 12.0 0.0 0.53 10.8 0.0 1.6 2 0 0 2 2 2 0 Selenium binding protein Glyco_hydro_16 PF00722.21 CEH15581.1 - 6.6e-14 51.8 0.0 1.2e-13 50.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 CEH15582.1 - 1.2e-46 159.1 4.4 1.2e-46 159.1 4.4 2.1 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CEH15582.1 - 1.7e-06 27.9 0.0 4.8e-05 23.2 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CEH15582.1 - 0.0015 18.5 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CEH15582.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 PAN_4 PF14295.6 CEH15583.1 - 0.00031 20.6 8.0 0.13 12.1 2.8 2.9 2 1 1 3 3 3 2 PAN domain Abhydrolase_1 PF00561.20 CEH15583.1 - 0.019 14.6 0.2 0.14 11.8 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold WSC PF01822.19 CEH15584.1 - 7.2e-119 388.2 161.9 8.8e-18 64.3 12.9 9.1 10 0 0 10 10 10 8 WSC domain Abhydrolase_5 PF12695.7 CEH15584.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family SpoIIIAH PF12685.7 CEH15584.1 - 3.7 7.3 7.7 4.7 7.0 0.6 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein WW PF00397.26 CEH15585.1 - 0.3 11.2 8.2 21 5.3 0.0 3.9 4 0 0 4 4 4 0 WW domain Phage_ABA_S PF18066.1 CEH15587.1 - 0.084 13.6 0.0 0.3 11.8 0.0 1.8 1 1 0 1 1 1 0 Phage ABA sandwich domain GTP_EFTU PF00009.27 CEH15588.1 - 6.7e-43 146.5 0.0 9.7e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CEH15588.1 - 1.4e-36 125.8 3.4 2.4e-36 125.0 3.4 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CEH15588.1 - 1.8e-23 82.6 0.0 3.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CEH15588.1 - 4.8e-20 71.4 0.0 1.9e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CEH15588.1 - 1.2e-09 38.4 0.3 8.4e-09 35.7 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CEH15588.1 - 5e-06 26.5 0.1 5e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CEH15588.1 - 3.4e-05 23.9 0.1 6.7e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CEH15588.1 - 0.0095 15.4 0.0 0.035 13.5 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CEH15588.1 - 0.044 13.4 0.0 0.15 11.7 0.0 1.8 1 1 0 1 1 1 0 Ras family Cyclin_N PF00134.23 CEH15589.1 - 5.3e-09 35.9 0.0 2.2e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain Defensin_2 PF01097.18 CEH15591.1 - 2e-05 24.4 17.4 0.0053 16.7 2.5 2.3 2 0 0 2 2 2 2 Arthropod defensin Toxin_3 PF00537.18 CEH15591.1 - 0.017 15.3 5.8 0.017 15.3 5.8 2.2 2 0 0 2 2 2 0 Scorpion toxin-like domain Gamma-thionin PF00304.20 CEH15591.1 - 0.083 13.2 18.2 0.77 10.1 3.7 2.3 2 0 0 2 2 2 0 Gamma-thionin family Miga PF10265.9 CEH15594.1 - 0.07 12.1 3.5 0.09 11.7 3.5 1.0 1 0 0 1 1 1 0 Mitoguardin OMP_b-brl PF13505.6 CEH15596.1 - 0.15 12.2 0.1 0.15 12.2 0.1 1.2 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain WD40 PF00400.32 CEH15598.1 - 4.2e-24 84.4 1.9 2.9e-06 27.9 0.0 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat Sof1 PF04158.14 CEH15598.1 - 7.8e-24 83.8 6.9 1.2e-23 83.1 6.9 1.3 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 CEH15598.1 - 5.6e-05 23.4 0.0 1.1 9.6 0.0 4.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_1 PF00561.20 CEH15599.1 - 2.2e-15 57.0 0.4 1.7e-14 54.1 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH15599.1 - 9.8e-14 51.2 0.9 1.8e-13 50.3 0.9 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEH15599.1 - 3.1e-10 41.0 0.0 3.8e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 CEH15599.1 - 0.0008 18.2 0.1 0.0094 14.7 0.1 2.1 1 1 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 CEH15599.1 - 0.011 14.7 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.20 CEH15599.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain WD40 PF00400.32 CEH15600.1 - 2e-21 75.9 17.5 7.8e-08 32.9 0.1 6.7 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH15600.1 - 8.9e-08 32.3 0.1 0.088 13.1 0.0 4.7 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEH15600.1 - 0.042 13.7 0.0 7 6.5 0.0 3.0 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A TFIID_20kDa PF03847.13 CEH15601.1 - 8.8e-32 109.4 0.4 1.2e-31 109.0 0.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 CEH15601.1 - 0.053 13.6 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 CEH15601.1 - 0.095 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aldo_ket_red PF00248.21 CEH15604.1 - 1.2e-15 57.4 0.0 3.6e-07 29.7 0.0 3.1 3 0 0 3 3 3 3 Aldo/keto reductase family ADH_zinc_N PF00107.26 CEH15605.1 - 6.5e-25 87.6 0.0 1e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEH15605.1 - 7.1e-13 49.8 0.0 1.8e-12 48.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH15605.1 - 7.1e-07 29.1 0.0 3.2e-06 27.0 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Peptidase_S8 PF00082.22 CEH15607.1 - 9e-37 126.9 3.2 1.3e-36 126.4 3.2 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CEH15607.1 - 6.4e-26 90.2 0.2 1.5e-25 89.1 0.2 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CEH15607.1 - 0.0032 18.2 2.4 0.04 14.7 0.0 2.6 2 0 0 2 2 2 1 Peptidase S8 pro-domain Syja_N PF02383.18 CEH15608.1 - 1.1e-85 287.8 0.0 1.5e-85 287.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 CEH15608.1 - 1.3e-25 89.3 0.0 2.6e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase ATP_synt_H PF05493.13 CEH15609.1 - 2.2e-23 82.5 2.6 2.6e-23 82.2 2.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.6 CEH15609.1 - 0.027 14.6 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix APH PF01636.23 CEH15610.1 - 1.7e-09 38.0 2.9 3.2e-09 37.1 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEH15610.1 - 2.8e-09 36.9 0.0 3.4e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase Asp PF00026.23 CEH15611.1 - 2.3e-65 221.1 1.0 2.3e-65 221.1 1.0 1.4 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEH15611.1 - 9.1e-08 32.5 4.0 0.00049 20.4 0.1 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal ArfGap PF01412.18 CEH15611.1 - 0.019 15.0 0.0 0.058 13.5 0.0 1.7 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf gag-asp_proteas PF13975.6 CEH15611.1 - 0.026 15.1 0.4 2.4 8.8 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Lysis_col PF02402.16 CEH15611.1 - 0.044 13.5 0.5 19 5.0 0.1 3.1 3 0 0 3 3 3 0 Lysis protein Peptidase_M24 PF00557.24 CEH15612.1 - 1.1e-38 133.1 0.1 1.7e-38 132.5 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF19 PF01579.18 CEH15614.1 - 0.041 13.7 0.1 0.05 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF19) DUF1281 PF06924.11 CEH15614.1 - 0.043 13.4 0.0 0.044 13.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) CoatB PF10389.9 CEH15615.1 - 0.0082 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Bacteriophage coat protein B Chitin_synth_1 PF01644.17 CEH15616.1 - 1e-66 223.9 0.9 1.5e-66 223.4 0.9 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 CEH15616.1 - 7.6e-27 94.1 0.5 1.2e-20 73.7 0.0 3.0 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 CEH15616.1 - 3.3e-23 81.4 0.1 1e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 CEH15616.1 - 1e-09 38.6 0.3 1e-09 38.6 0.3 2.4 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEH15616.1 - 0.022 14.6 0.0 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF3488 PF11992.8 CEH15616.1 - 0.08 11.9 6.1 0.16 10.9 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Aminotran_5 PF00266.19 CEH15618.1 - 1.4e-30 106.5 0.0 1.9e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Doppel PF11466.8 CEH15619.1 - 0.25 11.0 1.9 16 5.2 0.0 3.0 3 0 0 3 3 3 0 Prion-like protein Doppel DUF1748 PF08520.10 CEH15620.1 - 8.7e-21 73.6 0.0 1.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Asp PF00026.23 CEH15622.1 - 9.2e-61 206.0 0.1 1.1e-60 205.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEH15622.1 - 6.5e-14 52.5 1.5 6e-12 46.2 0.3 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CEH15622.1 - 0.016 15.8 0.6 5.6 7.7 0.1 2.8 2 1 0 2 2 2 0 Aspartyl protease DUF3809 PF12723.7 CEH15622.1 - 0.16 12.2 0.1 0.5 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3809) Pyocin_S PF06958.12 CEH15623.1 - 0.075 13.6 2.8 0.11 13.1 2.8 1.2 1 0 0 1 1 1 0 S-type Pyocin Roughex PF06020.11 CEH15623.1 - 0.19 10.8 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein UQ_con PF00179.26 CEH15624.1 - 7.5e-39 132.6 0.1 9.7e-39 132.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CEH15624.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.4 1 1 0 1 1 1 0 UEV domain 6PF2K PF01591.18 CEH15626.1 - 1.3e-70 237.2 0.0 1.8e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEH15626.1 - 6.2e-23 81.5 0.0 2.9e-20 72.8 0.0 3.1 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CEH15626.1 - 1.8e-07 31.4 0.0 5.8e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF4850 PF16142.5 CEH15626.1 - 0.069 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) GBP PF02263.19 CEH15626.1 - 0.099 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain KTI12 PF08433.10 CEH15626.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SKG6 PF08693.10 CEH15628.1 - 0.18 11.2 8.5 0.31 10.5 8.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Myc_target_1 PF15179.6 CEH15628.1 - 0.62 9.9 4.7 0.094 12.6 0.6 1.6 2 0 0 2 2 2 0 Myc target protein 1 Transket_pyr PF02779.24 CEH15630.1 - 2.9e-45 154.1 0.0 4.4e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CEH15630.1 - 1.7e-38 131.3 0.0 2.7e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CEH15630.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II COX15-CtaA PF02628.15 CEH15631.1 - 1.1e-88 297.4 6.2 2.3e-88 296.4 6.2 1.5 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein DUF1467 PF07330.12 CEH15631.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1467) Pribosyltran_N PF13793.6 CEH15632.1 - 9e-44 148.1 0.2 7e-43 145.3 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CEH15632.1 - 1.3e-39 136.2 3.6 4.6e-33 114.8 0.3 2.9 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CEH15632.1 - 9.2e-14 51.3 2.2 1.5e-13 50.6 0.4 2.1 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CEH15632.1 - 0.011 15.1 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase RNase_PH PF01138.21 CEH15632.1 - 0.056 13.9 0.1 0.45 11.0 0.1 2.2 2 0 0 2 2 2 0 3' exoribonuclease family, domain 1 Iso_dh PF00180.20 CEH15634.1 - 8.6e-75 252.0 0.0 1e-74 251.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RRM_1 PF00076.22 CEH15635.1 - 6.7e-09 35.5 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LsmAD PF06741.13 CEH15637.1 - 2.9e-23 82.2 2.0 5e-23 81.4 2.0 1.3 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 CEH15637.1 - 2.6e-10 40.3 0.0 4.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain AMP-binding PF00501.28 CEH15638.1 - 1.1e-48 165.9 0.0 1.3e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Ig_Tie2_1 PF10430.9 CEH15638.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 AMP-binding PF00501.28 CEH15639.1 - 3.1e-09 35.9 0.2 5e-09 35.3 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEH15639.1 - 4.7e-05 24.3 0.5 7.6e-05 23.6 0.5 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-B_box PF00643.24 CEH15640.1 - 0.0024 18.0 3.6 0.0024 18.0 3.6 1.9 2 0 0 2 2 2 1 B-box zinc finger DUF4573 PF15140.6 CEH15640.1 - 0.023 14.5 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) Fungal_trans PF04082.18 CEH15641.1 - 2.9e-18 65.9 0.6 4.9e-18 65.1 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH15641.1 - 0.00011 22.2 15.0 0.00022 21.3 15.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAGK_cat PF00781.24 CEH15642.1 - 2.2e-13 49.9 0.0 5.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain LCCL PF03815.19 CEH15644.1 - 1.1e-13 51.1 0.0 2.2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 LCCL domain DUF1308 PF07000.11 CEH15644.1 - 0.011 15.7 0.5 0.069 13.1 0.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1308) DUF5614 PF18474.1 CEH15644.1 - 0.074 12.3 0.2 0.23 10.8 0.1 1.8 3 0 0 3 3 3 0 Family of unknown function (DUF5614) DUF3413 PF11893.8 CEH15644.1 - 8.5 5.5 8.1 0.4 9.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Gpi1 PF05024.15 CEH15645.1 - 2.5e-59 200.5 4.4 4.3e-59 199.8 4.4 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Mad3_BUB1_I PF08311.12 CEH15646.1 - 3.8e-34 117.3 0.1 7.1e-34 116.4 0.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 CEH15646.1 - 2.4e-09 37.0 0.0 1.3e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15646.1 - 0.002 17.5 0.0 0.0045 16.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase 6PGD PF00393.19 CEH15647.1 - 8.7e-128 425.7 0.0 1.1e-127 425.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CEH15647.1 - 1.9e-52 177.6 0.0 2.7e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CEH15647.1 - 0.013 16.1 0.1 0.028 15.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 CEH15647.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CoatB PF10389.9 CEH15647.1 - 0.39 10.6 2.8 0.83 9.5 0.4 2.3 2 0 0 2 2 2 0 Bacteriophage coat protein B G-gamma PF00631.22 CEH15648.1 - 1.3e-22 79.6 0.0 1.4e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain FPN1 PF06963.12 CEH15649.1 - 1.7e-111 372.9 10.2 2e-111 372.6 10.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Peptidase_A8 PF01252.18 CEH15649.1 - 0.12 12.6 0.2 0.12 12.6 0.2 3.3 2 1 2 4 4 4 0 Signal peptidase (SPase) II Herpes_gE PF02480.16 CEH15650.1 - 0.013 14.3 0.3 0.021 13.6 0.3 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 CEH15650.1 - 0.086 12.7 0.2 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family TMEM51 PF15345.6 CEH15650.1 - 2.3 8.0 14.1 0.35 10.7 0.1 3.5 2 1 2 4 4 4 0 Transmembrane protein 51 Glyoxal_oxid_N PF07250.11 CEH15651.1 - 2.2e-31 108.9 0.5 5.6e-28 97.8 0.2 3.8 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CEH15651.1 - 9.2e-25 86.8 0.4 2.1e-24 85.6 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) WD40 PF00400.32 CEH15652.1 - 5.9e-10 39.6 5.9 0.002 18.9 0.2 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH15652.1 - 3.2e-05 24.2 0.0 0.72 10.2 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Utp14 PF04615.13 CEH15653.1 - 0.25 9.9 44.0 0.39 9.2 44.0 1.3 1 0 0 1 1 1 0 Utp14 protein EAL PF00563.20 CEH15654.1 - 0.15 11.5 0.0 0.17 11.4 0.0 1.0 1 0 0 1 1 1 0 EAL domain Methyltransf_23 PF13489.6 CEH15656.1 - 8.3e-11 42.0 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH15656.1 - 3e-09 37.5 0.0 7e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH15656.1 - 7.5e-06 26.6 0.0 1.8e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH15656.1 - 4.1e-05 23.4 0.0 9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH15656.1 - 4.4e-05 24.0 0.0 8.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEH15656.1 - 0.00059 19.2 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 CEH15656.1 - 0.0045 16.5 0.0 0.0075 15.8 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Pox_MCEL PF03291.16 CEH15656.1 - 0.0075 15.4 0.0 0.056 12.5 0.0 1.9 2 0 0 2 2 2 1 mRNA capping enzyme NNMT_PNMT_TEMT PF01234.17 CEH15656.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family NodS PF05401.11 CEH15656.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Phage_holin_3_6 PF07332.11 CEH15657.1 - 4.3 7.4 12.5 0.28 11.2 5.2 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III VIT1 PF01988.19 CEH15657.1 - 6.1 6.6 9.1 2.4 8.0 6.1 1.8 2 0 0 2 2 2 0 VIT family SART-1 PF03343.13 CEH15659.1 - 1.5e-133 446.7 48.1 1.8e-133 446.4 48.1 1.1 1 0 0 1 1 1 1 SART-1 family G-patch_2 PF12656.7 CEH15660.1 - 1.7e-23 82.4 0.7 4.7e-23 81.1 0.7 1.8 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 CEH15660.1 - 3.7e-09 36.3 2.2 7.8e-09 35.3 2.2 1.6 1 0 0 1 1 1 1 G-patch domain ABC_membrane PF00664.23 CEH15661.1 - 1e-37 130.3 3.2 1.4e-37 129.9 3.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CEH15661.1 - 3.5e-35 121.5 0.0 8e-35 120.3 0.0 1.6 2 0 0 2 2 1 1 ABC transporter AAA_16 PF13191.6 CEH15661.1 - 0.0038 17.6 0.0 0.01 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CEH15661.1 - 0.0048 16.8 0.0 0.031 14.1 0.0 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CEH15661.1 - 0.0062 16.8 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CEH15661.1 - 0.015 15.3 0.0 0.15 12.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CEH15661.1 - 0.019 14.7 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 CEH15661.1 - 0.02 14.4 0.1 1.6 8.1 0.1 2.5 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 CEH15661.1 - 0.023 15.1 0.0 0.2 12.1 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CEH15661.1 - 0.039 13.9 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 CEH15661.1 - 0.044 13.8 0.0 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 CEH15661.1 - 0.052 13.3 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_23 PF13476.6 CEH15661.1 - 0.055 14.0 0.3 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CEH15661.1 - 0.06 13.6 0.1 4.4 7.5 0.1 2.4 1 1 0 2 2 2 0 AAA domain DUF3987 PF13148.6 CEH15661.1 - 0.076 12.0 0.1 0.25 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.23 CEH15661.1 - 0.15 12.2 0.0 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 CEH15661.1 - 0.15 12.6 0.0 0.48 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Acyltransferase PF01553.21 CEH15663.1 - 1.6e-19 69.8 0.0 3.3e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase ComS PF17584.2 CEH15663.1 - 0.35 10.4 0.1 0.35 10.4 0.1 2.0 2 0 0 2 2 2 0 Bacillus competence protein S MFS_1 PF07690.16 CEH15665.1 - 6e-29 101.1 30.3 9.5e-29 100.4 30.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily 4HBT_2 PF13279.6 CEH15666.1 - 3.4e-10 40.5 0.0 9.3e-10 39.1 0.0 1.6 1 1 1 2 2 2 1 Thioesterase-like superfamily 4HBT PF03061.22 CEH15666.1 - 8.8e-06 26.0 0.0 0.00019 21.7 0.0 2.5 1 1 1 2 2 2 1 Thioesterase superfamily COesterase PF00135.28 CEH15668.1 - 1.1e-77 262.1 0.0 1.4e-77 261.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CEH15668.1 - 6.1e-06 26.2 0.1 1.4e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEH15668.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lung_7-TM_R PF06814.13 CEH15669.1 - 4.3e-34 118.1 17.7 1.6e-33 116.3 17.7 1.7 1 1 0 1 1 1 1 Lung seven transmembrane receptor ICL PF00463.21 CEH15671.1 - 1.4e-165 551.8 0.5 1.6e-165 551.6 0.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CEH15671.1 - 0.00018 21.1 0.1 0.0003 20.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 CEH15671.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Carn_acyltransf PF00755.20 CEH15673.1 - 1.1e-192 641.8 0.0 1.3e-192 641.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Glycos_trans_3N PF02885.17 CEH15673.1 - 0.69 9.8 3.0 7.4 6.5 0.0 3.2 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Pkinase PF00069.25 CEH15674.1 - 1e-63 215.2 0.0 1.4e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15674.1 - 1.8e-28 99.5 0.0 3.2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEH15674.1 - 2.7e-14 53.6 0.1 1.1e-13 51.7 0.1 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 CEH15674.1 - 6.1e-09 36.1 0.0 2.4e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 CEH15674.1 - 2.7e-07 30.2 0.0 2.5e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CEH15674.1 - 0.0025 16.8 0.0 0.0048 15.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CEH15674.1 - 0.011 15.3 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEH15674.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CEH15674.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.24 CEH15675.1 - 7e-106 354.8 14.2 8.5e-106 354.5 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH15675.1 - 1.2e-14 54.1 38.7 1.1e-09 37.7 14.2 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily FliS PF02561.14 CEH15676.1 - 0.0027 18.0 0.0 0.0036 17.6 0.0 1.2 1 0 0 1 1 1 1 Flagellar protein FliS Methyltransf_3 PF01596.17 CEH15677.1 - 6.6e-29 100.6 0.0 8.1e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 CEH15677.1 - 8.6e-06 26.7 0.0 1.4e-05 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_4 PF07993.12 CEH15678.1 - 6.3e-25 87.8 0.0 3.3e-24 85.4 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 CEH15678.1 - 2.2e-06 27.3 0.0 4.7e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CEH15678.1 - 7.3e-06 26.3 0.1 4.5e-05 23.7 0.1 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.10 CEH15678.1 - 5.5e-05 23.2 0.5 0.00015 21.7 0.5 1.8 1 1 0 1 1 1 1 KR domain LPD15 PF18828.1 CEH15678.1 - 0.0023 17.7 0.2 2.7 7.9 0.0 2.6 2 0 0 2 2 2 2 Large polyvalent-protein-associated domain 15 AMP-binding_C PF13193.6 CEH15678.1 - 0.0027 18.7 0.0 1.1 10.3 0.0 3.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.17 CEH15678.1 - 0.015 14.4 0.4 3.1 6.8 0.0 2.4 2 0 0 2 2 2 0 RmlD substrate binding domain Aldo_ket_red PF00248.21 CEH15679.1 - 2.7e-68 230.3 0.0 3.1e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AP_endonuc_2 PF01261.24 CEH15679.1 - 0.12 11.8 0.0 0.45 9.9 0.0 1.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DHQ_synthase PF01761.20 CEH15680.1 - 4.6e-47 160.4 0.0 6.1e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 CEH15680.1 - 1.5e-11 44.5 0.0 2.1e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Peptidase_M28 PF04389.17 CEH15681.1 - 1.7e-24 86.6 0.0 2.3e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CEH15681.1 - 6.2e-08 32.6 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TPR_2 PF07719.17 CEH15682.1 - 6.6e-27 91.4 7.9 8.1e-05 22.4 0.0 9.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 CEH15682.1 - 3.7e-21 74.0 0.1 0.00038 20.1 0.0 7.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEH15682.1 - 1e-14 53.4 0.1 0.066 13.5 0.0 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 CEH15682.1 - 2.2e-12 47.1 17.6 1.1e-08 35.2 1.5 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH15682.1 - 5.6e-12 45.7 10.2 0.00011 22.3 0.2 4.9 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CEH15682.1 - 6.5e-10 39.5 20.5 5.8e-05 23.7 0.1 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEH15682.1 - 4.2e-09 36.0 1.1 0.02 14.5 0.0 6.7 7 1 1 8 8 8 2 TPR repeat TPR_14 PF13428.6 CEH15682.1 - 3.7e-08 33.5 14.5 0.16 12.9 0.1 8.0 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 CEH15682.1 - 1.1e-06 28.9 0.1 4.6 8.1 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEH15682.1 - 1.8e-06 28.4 5.4 8.1 7.0 0.0 6.5 5 1 3 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEH15682.1 - 5.3e-06 26.4 3.0 0.19 12.2 0.0 6.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEH15682.1 - 1.5e-05 24.7 3.1 1.1 9.5 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEH15682.1 - 5.6e-05 23.2 9.8 0.11 12.6 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEH15682.1 - 0.0024 17.7 11.2 0.029 14.2 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 CEH15682.1 - 0.46 11.2 13.1 2.5 9.0 0.5 6.3 6 1 1 7 7 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CEH15682.1 - 1.4 8.2 16.0 0.015 14.6 2.9 3.6 4 1 2 6 6 6 0 MalT-like TPR region TPR_20 PF14561.6 CEH15682.1 - 6.7 7.1 8.8 2.5 8.5 0.1 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat Peptidase_M18 PF02127.15 CEH15683.1 - 6.6e-159 529.3 0.0 7.8e-159 529.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CEH15683.1 - 0.001 18.2 0.0 0.39 9.7 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase CAF1C_H4-bd PF12265.8 CEH15684.1 - 1.1e-14 54.4 0.0 4.2e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CEH15684.1 - 1.4e-12 47.9 11.8 3.3e-06 27.7 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.11 CEH15684.1 - 1.1e-05 25.5 0.0 0.00014 21.8 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CEH15684.1 - 4.8e-05 23.6 0.5 0.029 14.7 0.2 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PMP22_Claudin PF00822.20 CEH15685.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Ferritin_2 PF13668.6 CEH15687.1 - 1.3e-41 142.0 5.9 2.7e-41 140.9 5.9 1.6 1 0 0 1 1 1 1 Ferritin-like domain Fungal_trans_2 PF11951.8 CEH15688.1 - 3.7e-07 29.3 2.7 6.9e-06 25.1 3.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain PEX11 PF05648.14 CEH15689.1 - 4.7e-60 202.8 2.4 5.3e-60 202.7 2.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_C74 PF12387.8 CEH15689.1 - 0.17 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Haspin_kinase PF12330.8 CEH15690.1 - 3e-57 194.3 0.0 5.1e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEH15690.1 - 0.26 11.2 3.1 1 9.2 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family RCC1 PF00415.18 CEH15691.1 - 9.3e-18 64.6 21.9 0.00014 22.4 0.2 8.6 7 3 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEH15691.1 - 1.3e-06 28.0 32.6 0.013 15.3 0.5 8.1 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.22 CEH15692.1 - 1.6e-06 27.8 0.0 4.1e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AdoMet_MTase PF07757.13 CEH15693.1 - 1.6e-33 115.4 0.3 1.5e-15 57.5 0.1 2.4 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 CEH15693.1 - 0.02 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain M20_dimer PF07687.14 CEH15694.1 - 2.9e-11 43.3 0.1 1.3e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 CEH15694.1 - 1.8e-08 34.3 0.0 2.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TLD PF07534.16 CEH15695.1 - 2.7e-25 89.2 0.0 8.9e-24 84.3 0.0 2.5 2 0 0 2 2 2 1 TLD Ribosomal_L1 PF00687.21 CEH15696.1 - 3.3e-17 62.9 0.0 2.9e-16 59.8 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF2_N PF00176.23 CEH15697.1 - 2.3e-50 171.3 0.0 5e-50 170.2 0.0 1.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEH15697.1 - 5.4e-21 75.0 0.0 1.1e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CEH15697.1 - 9.7e-11 41.4 0.0 2.6e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 CEH15697.1 - 0.00012 22.2 0.0 0.00072 19.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.24 CEH15697.1 - 0.02 14.8 0.1 0.21 11.5 0.0 2.5 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Sas10_Utp3 PF04000.15 CEH15698.1 - 2.8e-11 43.9 1.7 2.8e-11 43.9 1.7 3.4 2 2 0 2 2 2 1 Sas10/Utp3/C1D family SpoIIIAH PF12685.7 CEH15698.1 - 3.7 7.3 14.5 9.1 6.0 10.9 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein PP-binding PF00550.25 CEH15701.1 - 1.3e-14 54.3 0.3 1.9e-14 53.7 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CEH15701.1 - 7.5e-06 26.1 0.1 1.1e-05 25.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier ABC1 PF03109.16 CEH15702.1 - 1.1e-21 77.2 0.0 3.1e-14 53.2 0.0 2.3 2 0 0 2 2 2 2 ABC1 family RhoGEF PF00621.20 CEH15703.1 - 1.2e-34 120.2 0.0 1.9e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 CEH15703.1 - 2e-07 30.7 0.2 0.017 14.8 0.1 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CEH15703.1 - 0.0036 17.7 0.9 1 9.9 0.1 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEH15703.1 - 0.051 14.1 0.6 20 6.2 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat Pkr1 PF08636.10 CEH15704.1 - 3.7e-21 75.0 0.1 4.7e-21 74.7 0.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 ABC-3 PF00950.17 CEH15704.1 - 0.0037 16.8 0.2 0.004 16.7 0.2 1.1 1 0 0 1 1 1 1 ABC 3 transport family SKIP_SNW PF02731.15 CEH15705.1 - 5.2e-69 231.0 0.3 5.2e-69 231.0 0.3 2.2 2 0 0 2 2 2 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.12 CEH15705.1 - 0.0004 20.2 10.6 0.0011 18.7 10.6 1.7 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein FAM199X PF15814.5 CEH15705.1 - 2.9 6.9 8.3 4.9 6.1 8.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X ApbA_C PF08546.11 CEH15706.1 - 1.4e-32 112.5 0.1 2.5e-32 111.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CEH15706.1 - 6.2e-17 61.6 0.0 5.1e-13 48.9 0.0 2.8 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA AMP-binding PF00501.28 CEH15707.1 - 3.8e-49 167.4 0.0 5.9e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CEH15707.1 - 1.7e-12 47.5 0.4 3.9e-12 46.4 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 CEH15707.1 - 6.1e-11 41.6 3.7 0.0054 16.4 0.0 6.6 6 1 1 7 7 7 3 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 CEH15707.1 - 3e-05 24.9 2.2 0.046 14.7 0.0 3.6 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain GH3 PF03321.13 CEH15707.1 - 0.062 12.1 0.0 1.9 7.2 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Hexapep_2 PF14602.6 CEH15707.1 - 0.11 12.3 7.9 4 7.3 0.0 4.8 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase Pox_A12 PF04651.13 CEH15708.1 - 0.35 10.9 4.9 0.087 12.9 0.8 1.9 2 0 0 2 2 2 0 Poxvirus A12 protein Myb_Cef PF11831.8 CEH15710.1 - 1.6e-59 201.4 5.3 1.6e-59 201.4 5.3 4.5 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 CEH15710.1 - 1.6e-22 79.4 6.0 4.1e-11 42.9 1.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH15710.1 - 5.8e-20 71.3 7.8 3e-13 49.8 3.8 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 CEH15710.1 - 0.0017 18.1 0.6 0.88 9.5 0.0 3.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain Cpn60_TCP1 PF00118.24 CEH15711.1 - 4.6e-148 493.9 0.8 5.7e-148 493.6 0.8 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PLDc PF00614.22 CEH15711.1 - 0.17 12.1 0.3 35 4.8 0.0 2.5 2 0 0 2 2 2 0 Phospholipase D Active site motif Enolase_N PF03952.16 CEH15711.1 - 0.57 10.3 6.1 0.5 10.5 0.1 3.1 3 0 0 3 3 3 0 Enolase, N-terminal domain RNA_pol_L_2 PF13656.6 CEH15712.1 - 5.3e-29 99.8 0.0 1e-28 98.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CEH15712.1 - 2.2e-10 39.8 0.0 3.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF4335 PF14233.6 CEH15712.1 - 0.046 13.6 0.1 0.28 11.1 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4335) SRP68 PF16969.5 CEH15713.1 - 2.9e-49 168.5 21.6 2.3e-43 149.1 7.6 3.2 2 1 0 2 2 2 2 RNA-binding signal recognition particle 68 LIDHydrolase PF10230.9 CEH15714.1 - 1.3e-43 149.5 0.0 2.8e-43 148.4 0.0 1.5 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CEH15714.1 - 0.00011 22.9 12.3 0.00024 21.8 11.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH15714.1 - 0.00097 18.5 0.0 0.002 17.4 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH15714.1 - 0.0022 17.7 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CEH15714.1 - 0.071 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Ras PF00071.22 CEH15715.1 - 2.2e-54 183.4 0.0 2.5e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH15715.1 - 7.5e-22 77.8 0.0 9.7e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH15715.1 - 1.6e-05 24.4 0.0 2.2e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Tetraspanin PF00335.20 CEH15716.1 - 0.33 10.6 10.5 0.029 14.1 4.6 1.9 1 1 1 2 2 2 0 Tetraspanin family DUF4231 PF14015.6 CEH15716.1 - 5.8 7.4 8.5 0.71 10.4 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) GTP_EFTU PF00009.27 CEH15719.1 - 5.5e-67 225.1 0.3 7.5e-67 224.6 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CEH15719.1 - 1.3e-33 115.3 0.0 3.4e-33 114.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CEH15719.1 - 2.9e-17 62.5 0.0 6.7e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CEH15719.1 - 2.2e-14 53.3 0.0 6e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CEH15719.1 - 3.1e-13 49.9 0.0 1e-12 48.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEH15719.1 - 1.1e-05 25.4 0.1 2.3e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase CN_hydrolase PF00795.22 CEH15720.1 - 5.6e-11 42.3 0.4 1.2e-05 24.8 0.0 2.7 4 0 0 4 4 4 2 Carbon-nitrogen hydrolase Kelch_4 PF13418.6 CEH15721.1 - 3.8e-29 100.4 13.1 1e-10 41.5 0.6 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CEH15721.1 - 3.2e-27 94.2 9.5 3.9e-10 39.8 0.1 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CEH15721.1 - 3.8e-25 87.2 10.4 1.7e-11 43.5 0.3 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CEH15721.1 - 3.4e-22 77.9 10.0 4.8e-10 39.4 0.3 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_5 PF13854.6 CEH15721.1 - 1.6e-21 75.8 6.2 1.5e-07 31.2 0.1 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CEH15721.1 - 3.8e-16 58.4 7.5 1.3e-05 25.0 0.1 5.4 5 0 0 5 5 5 4 Kelch motif DUF3240 PF11582.8 CEH15721.1 - 0.22 11.7 1.0 1.2 9.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3240) Vac_Fusion PF02346.16 CEH15721.1 - 7.1 6.3 9.5 23 4.7 1.2 4.1 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 ApoO PF09769.9 CEH15721.1 - 7.2 6.6 13.8 13 5.7 0.3 4.9 3 2 1 4 4 4 0 Apolipoprotein O WD40 PF00400.32 CEH15723.1 - 1.5e-16 60.4 9.7 6.3e-05 23.7 0.3 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH15723.1 - 2e-16 60.0 4.5 1.6e-05 25.1 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEH15723.1 - 0.0069 15.4 0.1 0.15 11.0 0.0 2.8 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 CEH15723.1 - 0.032 12.3 1.1 1.4 6.8 0.0 2.5 3 0 0 3 3 3 0 IKI3 family PRP38 PF03371.15 CEH15724.1 - 2.1e-56 190.5 0.2 2.4e-56 190.3 0.2 1.0 1 0 0 1 1 1 1 PRP38 family DASH_Ask1 PF08655.10 CEH15725.1 - 7.5e-25 86.6 0.0 1.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Ask1 DUF2059 PF09832.9 CEH15726.1 - 0.027 14.5 1.4 4 7.6 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) RNA_pol_A_bac PF01000.26 CEH15727.1 - 7.7e-25 87.5 0.0 1.3e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CEH15727.1 - 3e-20 71.4 0.0 5.1e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RRM_1 PF00076.22 CEH15728.1 - 4.3e-13 48.9 0.1 8.3e-10 38.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEH15728.1 - 7.8e-08 32.0 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ChapFlgA PF13144.6 CEH15728.1 - 0.018 15.1 1.5 6.3 6.9 0.2 2.6 1 1 1 2 2 2 0 Chaperone for flagella basal body P-ring formation Draxin PF15550.6 CEH15728.1 - 0.024 14.5 8.1 0.036 13.9 8.1 1.2 1 0 0 1 1 1 0 Draxin Peptidase_C53 PF05550.11 CEH15728.1 - 0.2 11.3 0.1 1.6 8.3 0.0 2.1 1 1 0 2 2 2 0 Pestivirus Npro endopeptidase C53 TRAP-gamma PF07074.12 CEH15728.1 - 1.2 8.7 5.3 12 5.4 0.2 2.6 2 1 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) RBM39linker PF15519.6 CEH15728.1 - 7 7.8 7.1 27 5.9 0.1 2.9 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein VHS PF00790.19 CEH15729.1 - 1.6e-22 79.8 0.0 5.4e-22 78.2 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 CEH15729.1 - 1.5e-06 28.4 0.6 3.5e-06 27.2 0.6 1.7 1 0 0 1 1 1 1 GAT domain YqaH PF17448.2 CEH15729.1 - 0.027 14.8 0.3 0.095 13.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized YqaH-like Tfb4 PF03850.14 CEH15729.1 - 1.4 8.4 4.8 2.4 7.6 4.8 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF4210 PF13915.6 CEH15731.1 - 1.7e-25 89.4 0.0 3.3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) JmjC PF02373.22 CEH15731.1 - 0.0031 17.9 0.1 0.0052 17.2 0.1 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CEH15731.1 - 0.0033 17.2 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 CEH15731.1 - 0.0045 16.7 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CEH15731.1 - 0.073 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Cupin Cupin_4 PF08007.12 CEH15731.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein GPI PF06560.11 CEH15731.1 - 0.26 10.5 0.1 0.57 9.4 0.0 1.5 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Pkinase PF00069.25 CEH15733.1 - 2.6e-27 95.8 0.0 3.3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15733.1 - 6.5e-16 58.4 0.0 8.4e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH15733.1 - 1.1e-09 37.6 0.1 1.9e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEH15733.1 - 0.0006 19.8 0.0 0.0088 16.0 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CEH15733.1 - 0.022 14.1 0.1 0.15 11.4 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CEH15733.1 - 0.044 12.7 0.1 0.065 12.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sugar_tr PF00083.24 CEH15735.1 - 1.1e-102 344.3 19.1 1.4e-102 343.9 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH15735.1 - 2.6e-30 105.5 20.8 2.1e-29 102.6 22.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CEH15735.1 - 0.00077 18.4 0.7 0.011 14.6 0.0 2.2 1 1 1 2 2 2 2 MFS_1 like family Spt5_N PF11942.8 CEH15735.1 - 1.1 10.3 5.0 3.1 8.8 5.0 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2062 PF09835.9 CEH15735.1 - 4.6 7.1 10.1 2.4 8.0 0.1 3.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) PAC3 PF10178.9 CEH15736.1 - 0.0044 17.1 0.1 0.015 15.4 0.0 2.0 2 1 0 2 2 2 1 Proteasome assembly chaperone 3 DUF1178 PF06676.11 CEH15737.1 - 0.01 16.2 0.2 0.011 16.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) SNF2_N PF00176.23 CEH15738.1 - 7.8e-63 212.3 0.0 1e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEH15738.1 - 1.1e-12 48.2 0.0 2.7e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH15738.1 - 6.4e-09 36.0 0.1 3.8e-06 27.0 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 CEH15738.1 - 0.00033 20.6 6.1 0.00089 19.2 5.6 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CEH15738.1 - 0.0098 15.8 7.8 0.072 13.0 7.1 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEH15738.1 - 0.14 12.1 6.7 0.38 10.7 6.5 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEH15738.1 - 0.29 11.2 4.4 1 9.5 4.4 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 CEH15738.1 - 2.9 8.3 6.0 6.8 7.1 6.0 1.7 1 0 0 1 1 1 0 Ring finger domain QRPTase_C PF01729.19 CEH15739.1 - 2.5e-50 170.5 0.4 3.1e-50 170.2 0.4 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 CEH15739.1 - 7.3e-19 67.6 0.0 2.7e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain IPT PF01745.16 CEH15739.1 - 0.13 11.7 0.0 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 Isopentenyl transferase Tubulin PF00091.25 CEH15740.1 - 8.3e-61 205.6 0.0 1.1e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEH15740.1 - 1.4e-39 135.1 0.0 2.1e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CEH15740.1 - 1.3e-05 25.5 0.0 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CEH15740.1 - 0.0004 19.7 0.0 0.0008 18.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 CEH15740.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain RasGAP PF00616.19 CEH15740.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.4 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Pkinase PF00069.25 CEH15741.1 - 9.8e-49 166.1 0.0 2e-48 165.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15741.1 - 5.2e-22 78.4 0.0 7.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH15741.1 - 0.00025 20.5 0.0 0.0005 19.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEH15741.1 - 0.16 10.7 0.1 0.37 9.5 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase zf-C2H2 PF00096.26 CEH15742.1 - 1.8e-08 34.4 17.2 4.8e-05 23.6 2.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEH15742.1 - 1.2e-05 25.5 9.9 1.4e-05 25.3 3.5 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CEH15742.1 - 0.00042 20.5 0.2 0.0011 19.2 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CEH15742.1 - 0.00083 20.0 12.8 0.0018 19.0 1.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEH15742.1 - 0.0019 18.1 0.5 0.0047 16.9 0.5 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 CEH15742.1 - 0.0022 18.3 3.7 0.0068 16.8 0.4 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 CEH15742.1 - 0.0022 18.6 13.4 0.02 15.5 0.3 3.2 1 1 2 3 3 3 2 FOXP coiled-coil domain NARP1 PF12569.8 CEH15743.1 - 2e-139 465.9 3.7 2e-139 465.9 3.7 1.6 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CEH15743.1 - 2.1e-13 49.3 17.7 0.00032 20.6 0.0 11.2 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEH15743.1 - 2.8e-10 39.6 0.1 0.00054 19.7 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEH15743.1 - 3.9e-09 36.6 35.3 0.0031 18.2 0.0 12.1 9 5 6 15 15 15 4 Tetratricopeptide repeat TPR_19 PF14559.6 CEH15743.1 - 7.2e-09 36.0 26.3 0.65 10.6 5.5 8.1 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEH15743.1 - 3.3e-06 27.7 40.3 0.074 13.7 0.1 10.7 8 3 2 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEH15743.1 - 0.0018 18.4 0.3 0.0018 18.4 0.3 6.8 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEH15743.1 - 0.0039 17.3 11.1 0.51 10.7 0.5 7.2 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEH15743.1 - 0.005 17.4 18.8 4.1 8.3 0.6 9.2 11 2 1 12 12 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEH15743.1 - 0.01 15.8 14.7 5.9 7.2 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEH15743.1 - 0.025 14.8 23.2 0.78 10.1 0.0 7.1 7 1 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH15743.1 - 0.026 14.8 12.3 2.4 8.5 0.0 5.5 6 1 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5327 PF17261.2 CEH15743.1 - 0.072 13.8 0.5 0.3 11.9 0.5 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Fis1_TPR_C PF14853.6 CEH15743.1 - 0.085 12.9 1.1 27 4.9 0.0 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 CEH15743.1 - 0.27 10.9 1.4 11 5.8 0.0 3.6 3 0 0 3 3 3 0 TPR repeat TPR_4 PF07721.14 CEH15743.1 - 4.6 8.2 39.2 0.57 11.0 0.2 8.6 9 0 0 9 9 8 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 CEH15745.1 - 0.023 15.5 0.9 0.07 14.0 0.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.12 CEH15745.1 - 0.087 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Esterase_phd PF10503.9 CEH15746.1 - 0.023 14.2 0.8 0.2 11.1 0.0 2.4 3 0 0 3 3 3 0 Esterase PHB depolymerase Lipase_3 PF01764.25 CEH15746.1 - 0.038 13.8 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) SPX PF03105.19 CEH15746.1 - 0.058 13.3 3.5 0.066 13.1 3.5 1.1 1 0 0 1 1 1 0 SPX domain DUF4551 PF15087.6 CEH15746.1 - 1.1 8.1 2.9 1.4 7.6 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Menin PF05053.13 CEH15746.1 - 2.1 6.6 3.8 2.8 6.2 3.8 1.1 1 0 0 1 1 1 0 Menin Miga PF10265.9 CEH15746.1 - 2.2 7.1 4.3 3.2 6.6 4.3 1.1 1 0 0 1 1 1 0 Mitoguardin PAP1 PF08601.10 CEH15746.1 - 4.8 6.8 15.4 7.1 6.2 15.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.9 CEH15746.1 - 5.2 5.8 7.5 8.5 5.1 7.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNase_H2_suC PF08615.11 CEH15747.1 - 7.1e-16 58.7 0.0 3.6e-15 56.4 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SMYLE_N PF18615.1 CEH15747.1 - 0.2 11.1 3.5 0.24 10.9 3.5 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain HORMA PF02301.18 CEH15748.1 - 3.5e-07 30.0 0.0 8.8e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 HORMA domain CENP-T_C PF15511.6 CEH15749.1 - 3.9e-14 52.7 0.0 5.5e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Trp_halogenase PF04820.14 CEH15749.1 - 0.079 11.8 0.0 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Glycophorin_A PF01102.18 CEH15750.1 - 0.023 14.9 1.0 0.034 14.4 1.0 1.3 1 0 0 1 1 1 0 Glycophorin A PAF PF15715.5 CEH15750.1 - 0.77 10.3 11.1 1.7 9.2 11.1 1.5 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Apt1 PF10351.9 CEH15750.1 - 6.2 5.5 6.1 7.1 5.4 6.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain LIP PF03583.14 CEH15751.1 - 5.8e-57 193.2 0.0 7.4e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.20 CEH15751.1 - 0.034 13.8 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold UQ_con PF00179.26 CEH15753.1 - 4.1e-45 152.9 0.0 4.6e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme WD40 PF00400.32 CEH15755.1 - 3.7e-32 109.8 11.2 8.1e-07 29.6 0.0 7.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH15755.1 - 6.8e-14 51.9 0.0 0.0015 18.8 0.1 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEH15755.1 - 5.1e-06 26.5 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEH15755.1 - 0.0036 16.7 0.0 0.16 11.2 0.0 2.5 2 1 1 3 3 3 1 WD40-like domain CBS PF00571.28 CEH15756.1 - 0.015 15.7 1.4 0.24 11.9 0.0 3.1 3 0 0 3 3 3 0 CBS domain DUF21 PF01595.20 CEH15757.1 - 2.2e-13 50.3 1.9 2.8e-13 50.0 0.1 1.8 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain Sulfate_transp PF00916.20 CEH15757.1 - 0.37 9.5 4.8 0.42 9.3 0.4 2.1 2 0 0 2 2 2 0 Sulfate permease family Pkr1 PF08636.10 CEH15757.1 - 1.3 9.2 6.4 0.53 10.5 2.3 2.2 2 0 0 2 2 2 0 ER protein Pkr1 PseudoU_synth_1 PF01416.20 CEH15761.1 - 8.5e-21 74.5 0.0 5.5e-17 62.2 0.0 3.5 3 0 0 3 3 3 2 tRNA pseudouridine synthase Transmemb_17 PF09799.9 CEH15762.1 - 0.05 14.2 12.6 0.36 11.4 0.0 3.2 2 1 1 3 3 3 0 Predicted membrane protein DUF3759 PF12585.8 CEH15763.1 - 1.6e-38 130.6 9.9 2e-38 130.3 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RNA_pol_Rpb2_6 PF00562.28 CEH15764.1 - 2.8e-126 421.7 0.2 4.7e-126 421.0 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CEH15764.1 - 5.8e-64 215.3 0.0 8.4e-64 214.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CEH15764.1 - 3.1e-42 144.4 0.0 7.3e-42 143.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CEH15764.1 - 3e-32 110.9 0.3 6.4e-32 109.8 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CEH15764.1 - 8.1e-25 86.8 0.1 2e-24 85.5 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 CEH15764.1 - 5.8e-24 84.2 0.7 1.2e-23 83.2 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 CEH15764.1 - 6.9e-20 71.4 1.0 1.6e-19 70.2 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 CEH15764.1 - 0.13 13.0 0.1 0.35 11.6 0.1 1.7 1 0 0 1 1 1 0 MRN-interacting protein RNA_POL_M_15KD PF02150.16 CEH15764.1 - 0.36 10.8 1.1 1 9.3 1.1 1.7 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Ribosomal_S28e PF01200.18 CEH15765.1 - 8.3e-31 105.8 2.1 9.2e-31 105.6 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e zf-ZPR1 PF03367.13 CEH15765.1 - 0.06 13.2 0.1 0.064 13.1 0.1 1.1 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Ribosomal_S7 PF00177.21 CEH15766.1 - 1.1e-36 125.7 1.4 1.4e-36 125.4 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e bZIP_1 PF00170.21 CEH15767.1 - 5.1e-10 39.3 2.4 1.3e-09 38.0 2.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor DUF3425 PF11905.8 CEH15767.1 - 1.4e-09 38.0 0.1 1.7e-08 34.5 0.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 CEH15767.1 - 0.00091 19.3 2.3 0.003 17.6 2.3 1.9 1 0 0 1 1 1 1 Basic region leucine zipper PTH2 PF01981.16 CEH15767.1 - 0.17 12.2 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 DUF4692 PF15763.5 CEH15767.1 - 1.3 9.5 3.4 3.2 8.2 3.4 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) NCBP3 PF10309.9 CEH15768.1 - 7.4e-07 28.9 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 CEH15768.1 - 0.0016 18.4 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain PfkB PF00294.24 CEH15769.1 - 5.5e-62 209.8 0.2 9.6e-62 209.0 0.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MutS_V PF00488.21 CEH15769.1 - 1.1e-45 156.0 3.0 3.2e-44 151.2 1.1 3.6 3 1 1 4 4 4 1 MutS domain V MutS_I PF01624.20 CEH15769.1 - 6.8e-10 39.2 0.2 5.8e-09 36.2 0.0 2.4 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 CEH15769.1 - 1.2e-07 32.1 1.2 0.0094 16.2 0.5 2.4 1 1 1 2 2 2 2 MutS domain III MutS_IV PF05190.18 CEH15769.1 - 1.9e-05 24.9 0.1 4e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV Phos_pyr_kin PF08543.12 CEH15769.1 - 0.002 17.6 0.0 0.0046 16.4 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DEC-1_C PF04626.13 CEH15769.1 - 0.018 15.4 0.2 0.045 14.2 0.2 1.6 1 0 0 1 1 1 0 Dec-1 protein, C terminal region Aldo_ket_red PF00248.21 CEH15771.1 - 2e-54 184.8 0.0 2.3e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tom5 PF10642.9 CEH15773.1 - 2.5e-17 62.6 0.1 2.7e-17 62.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Hepar_II_III PF07940.13 CEH15774.1 - 2.7e-09 37.0 0.1 5.3e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF4118 PF13493.6 CEH15775.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Ribosomal_L22e PF01776.17 CEH15776.1 - 2.8e-44 149.9 0.0 3.2e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Cupin_8 PF13621.6 CEH15777.1 - 9.6e-32 110.7 0.0 6.7e-21 75.2 0.0 3.3 2 1 1 3 3 3 2 Cupin-like domain Cupin_4 PF08007.12 CEH15777.1 - 0.071 12.6 2.3 0.3 10.5 0.0 2.9 3 1 0 3 3 3 0 Cupin superfamily protein Pcc1 PF09341.10 CEH15777.1 - 0.099 12.8 0.3 0.27 11.4 0.3 1.7 1 0 0 1 1 1 0 Transcription factor Pcc1 DIOX_N PF14226.6 CEH15778.1 - 8.2e-18 65.3 0.0 2e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CEH15778.1 - 3.8e-14 53.0 0.0 7.1e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prenylcys_lyase PF07156.14 CEH15780.1 - 3.8e-28 98.6 0.5 2e-27 96.3 0.5 1.8 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 CEH15780.1 - 2.9e-06 27.4 0.1 9.7e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEH15780.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEH15780.1 - 0.0019 18.2 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 CEH15780.1 - 0.0052 16.4 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CEH15780.1 - 0.024 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 CEH15780.1 - 0.049 12.9 0.2 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Thi4 family TAFII28 PF04719.14 CEH15780.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Prenylcys_lyase PF07156.14 CEH15781.1 - 8.5e-36 123.8 0.0 2.5e-20 72.9 0.0 2.1 2 0 0 2 2 2 2 Prenylcysteine lyase Pkinase PF00069.25 CEH15782.1 - 5.3e-63 212.8 0.0 1e-61 208.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15782.1 - 1.9e-34 119.1 0.0 3.5e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CEH15782.1 - 5.6e-21 74.2 21.4 2.4e-11 43.4 8.8 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 CEH15782.1 - 5.4e-19 68.1 19.1 3.2e-11 43.2 7.3 2.4 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 CEH15782.1 - 2.4e-08 34.6 1.0 7.3e-08 33.0 1.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 CEH15782.1 - 4.8e-06 26.8 0.1 9.9e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 CEH15782.1 - 0.0041 16.5 0.0 0.008 15.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CEH15782.1 - 0.031 13.9 0.3 2.4 7.8 0.1 2.5 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MSA-2c PF12238.8 CEH15782.1 - 0.041 13.9 0.3 0.041 13.9 0.3 2.8 2 0 0 2 2 1 0 Merozoite surface antigen 2c C1_2 PF03107.16 CEH15782.1 - 0.096 13.0 16.8 0.85 10.0 5.2 2.4 2 0 0 2 2 2 0 C1 domain DUF4407 PF14362.6 CEH15782.1 - 1.1 8.6 2.7 7.3 5.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Tropomyosin PF00261.20 CEH15782.1 - 3.2 7.1 10.0 5.6 6.3 1.1 2.3 2 0 0 2 2 2 0 Tropomyosin Rad17 PF03215.15 CEH15783.1 - 8.6e-20 71.4 0.0 2.5e-19 69.9 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CEH15783.1 - 4.9e-07 30.3 0.0 1.5e-06 28.7 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEH15783.1 - 3.3e-05 24.2 0.0 7.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CEH15783.1 - 0.016 15.7 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 CEH15783.1 - 0.045 14.3 0.0 0.085 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MbeB_N PF04837.12 CEH15783.1 - 0.077 13.3 0.2 7.8 6.9 0.1 2.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region AAA_assoc_2 PF16193.5 CEH15783.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain T2SSE PF00437.20 CEH15783.1 - 0.74 8.8 2.1 3.3 6.7 0.1 2.5 2 1 1 3 3 3 0 Type II/IV secretion system protein Cofilin_ADF PF00241.20 CEH15784.1 - 1.2e-39 134.8 0.1 1.4e-39 134.7 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Complex1_51K PF01512.17 CEH15785.1 - 2.9e-48 163.6 0.0 4.9e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CEH15785.1 - 1.2e-31 108.6 0.2 2.1e-31 107.8 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CEH15785.1 - 3.4e-08 33.2 0.0 9.6e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 SLBB domain SURF1 PF02104.15 CEH15786.1 - 2.8e-36 125.4 0.0 3.5e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 SURF1 family SNF2_N PF00176.23 CEH15787.1 - 3e-65 220.2 0.2 6.3e-65 219.2 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 CEH15787.1 - 3.7e-51 173.0 20.5 3.7e-51 173.0 20.5 4.6 5 0 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 CEH15787.1 - 3.7e-17 62.7 0.0 9.2e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH15787.1 - 1e-07 32.1 0.8 3.3e-07 30.4 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CEH15787.1 - 0.058 12.6 3.4 0.07 12.3 0.0 2.6 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 DUF1117 PF06547.12 CEH15787.1 - 0.79 10.3 5.9 0.74 10.4 2.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) bZIP_1 PF00170.21 CEH15789.1 - 6.3e-09 35.8 8.8 1.5e-07 31.4 6.8 2.4 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.9 CEH15789.1 - 2.5e-06 27.4 4.6 2.5e-06 27.4 4.6 2.2 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.15 CEH15789.1 - 0.022 14.8 1.0 0.022 14.8 1.0 3.4 3 0 0 3 3 3 0 Basic region leucine zipper Glyco_hydro_92 PF07971.12 CEH15790.1 - 1.4e-105 353.9 0.0 2.2e-105 353.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 CEH15790.1 - 4.5e-42 144.6 1.5 7.5e-42 143.9 1.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Kdo PF06293.14 CEH15791.1 - 2.4e-06 27.1 0.0 2.4e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CEH15791.1 - 4.8e-06 26.1 0.0 6.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CEH15791.1 - 0.0001 22.3 0.4 0.013 15.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 CEH15791.1 - 0.00057 19.3 0.0 0.0012 18.3 0.0 1.3 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 CEH15791.1 - 0.0031 16.4 0.0 0.0039 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) RIO1 PF01163.22 CEH15791.1 - 0.0046 16.6 0.0 0.099 12.2 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 CEH15791.1 - 0.011 15.1 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH15791.1 - 0.032 13.0 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Iron_traffic PF04362.14 CEH15791.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking SUR7 PF06687.12 CEH15793.1 - 2.1e-19 70.0 13.1 3.3e-19 69.4 13.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Rsm22 PF09243.10 CEH15794.1 - 1.4e-35 122.9 0.0 3e-11 43.1 0.0 4.5 4 1 0 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Zn_clus PF00172.18 CEH15795.1 - 0.00026 21.0 17.4 0.00039 20.5 17.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-AN1 PF01428.16 CEH15797.1 - 3.7e-07 30.2 2.0 5.3e-07 29.7 2.0 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger zf-C2HC5 PF06221.13 CEH15797.1 - 0.0099 15.8 0.4 0.015 15.3 0.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Pkinase PF00069.25 CEH15798.1 - 8e-68 228.7 0.0 1.2e-67 228.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15798.1 - 4e-28 98.4 0.0 6.4e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CEH15798.1 - 3.4e-05 23.5 0.1 6.9e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 CEH15798.1 - 0.00027 20.4 0.3 0.59 9.4 0.1 2.4 1 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 CEH15798.1 - 0.0014 17.7 0.1 0.0022 17.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEH15798.1 - 0.053 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH15798.1 - 0.35 10.7 3.5 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family XRCC4 PF06632.12 CEH15798.1 - 0.72 8.7 5.3 1.1 8.0 5.3 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 NARP1 PF12569.8 CEH15798.1 - 1.8 7.4 6.4 2.6 6.9 6.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 WD40 PF00400.32 CEH15800.1 - 6.9e-35 118.5 19.3 7.7e-09 36.1 0.1 8.3 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH15800.1 - 6.1e-21 74.5 0.1 0.0014 18.9 0.0 6.3 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CEH15800.1 - 0.00025 20.9 0.1 0.00065 19.6 0.1 1.8 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 CEH15800.1 - 0.003 16.3 0.0 0.26 9.9 0.0 3.3 4 0 0 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEH15800.1 - 0.01 14.8 0.0 7.7 5.4 0.0 3.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEH15800.1 - 0.025 14.5 0.0 0.14 12.0 0.0 2.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF1751 PF08551.10 CEH15801.1 - 4.3e-23 81.7 5.2 8.8e-23 80.8 2.6 2.4 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CEH15801.1 - 0.019 14.9 3.3 0.062 13.3 3.3 1.9 1 1 0 1 1 1 0 Rhomboid family VEGFR-2_TMD PF17988.1 CEH15801.1 - 2.1 7.9 6.9 0.12 11.8 0.9 2.0 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain Sel1 PF08238.12 CEH15802.1 - 8.7e-13 48.5 13.5 2.4e-07 31.2 0.2 5.7 6 0 0 6 6 6 3 Sel1 repeat TrbI PF03743.14 CEH15802.1 - 0.3 10.9 3.6 0.79 9.5 3.6 1.7 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein GARS_A PF01071.19 CEH15805.1 - 1.5e-68 230.4 0.0 1.8e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 CEH15805.1 - 0.012 15.6 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.17 CEH15805.1 - 0.049 13.1 0.1 0.066 12.7 0.1 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 CEH15805.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 CEH15805.1 - 0.16 11.2 0.0 5.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp AIRS_C PF02769.22 CEH15806.1 - 2.2e-27 96.1 0.0 5.6e-25 88.3 0.0 2.1 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 CEH15806.1 - 2.2e-09 37.9 0.9 3.7e-09 37.1 0.9 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Pkinase PF00069.25 CEH15807.1 - 5.7e-22 78.3 0.0 2.6e-21 76.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15807.1 - 1.5e-12 47.4 0.0 1e-11 44.7 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH15807.1 - 0.037 13.3 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF3958 PF13125.6 CEH15807.1 - 4.7 7.5 9.7 0.11 12.7 1.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) EXOSC1 PF10447.9 CEH15811.1 - 8.7e-25 87.5 0.3 3e-24 85.7 0.3 1.8 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 MreC PF04085.14 CEH15811.1 - 0.0058 16.5 0.1 0.013 15.4 0.1 1.5 1 1 0 1 1 1 1 rod shape-determining protein MreC ECR1_N PF14382.6 CEH15811.1 - 0.0075 16.1 1.5 0.027 14.3 1.5 2.0 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CPSF_A PF03178.15 CEH15812.1 - 1.7e-39 136.1 0.0 3.7e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CEH15812.1 - 5.1e-28 98.0 0.0 7.9e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF5546 PF17700.1 CEH15812.1 - 0.056 13.8 0.7 0.31 11.4 0.7 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5546) DivIC PF04977.15 CEH15813.1 - 3 7.7 5.8 18 5.2 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator SH3_9 PF14604.6 CEH15814.1 - 6.2e-22 77.2 1.2 5.3e-10 39.0 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CEH15814.1 - 4.8e-19 67.7 0.2 2.3e-09 36.7 0.1 2.5 2 0 0 2 2 2 2 SH3 domain FCH PF00611.23 CEH15814.1 - 1.9e-10 40.9 0.3 2.2e-09 37.5 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 CEH15814.1 - 4.9e-10 38.9 0.1 1.8e-06 27.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 CEH15814.1 - 0.093 13.0 0.7 0.27 11.6 0.2 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain SH3_10 PF17902.1 CEH15814.1 - 0.12 12.5 0.0 18 5.5 0.0 2.7 2 0 0 2 2 2 0 SH3 domain FAD-oxidase_C PF02913.19 CEH15816.1 - 1.8e-58 198.1 0.0 2.4e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CEH15816.1 - 2.1e-26 92.3 2.5 4.6e-12 45.8 0.3 3.3 1 1 2 3 3 3 3 FAD binding domain Nipped-B_C PF12830.7 CEH15817.1 - 5.2e-43 147.2 0.0 3.8e-42 144.4 0.0 2.4 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 CEH15817.1 - 8.6e-07 29.1 1.6 8.6e-07 29.1 1.6 2.3 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 CEH15817.1 - 0.00067 20.0 6.7 0.011 16.0 4.3 3.7 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 CEH15817.1 - 0.012 15.6 0.1 0.03 14.4 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CEH15817.1 - 0.064 13.8 6.0 0.33 11.5 0.3 3.7 2 1 2 4 4 4 0 HEAT-like repeat HEAT PF02985.22 CEH15817.1 - 1.1 9.7 8.7 0.46 10.9 0.1 3.9 4 0 0 4 4 4 0 HEAT repeat PAP2 PF01569.21 CEH15818.1 - 6.7e-14 51.8 4.4 5.9e-13 48.8 4.4 2.1 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 CEH15818.1 - 1.1e-05 25.5 0.9 4.9e-05 23.5 0.0 2.1 2 1 1 3 3 3 1 Divergent PAP2 family BP28CT PF08146.12 CEH15819.1 - 2.9e-25 89.0 1.6 6.3e-25 87.9 0.0 2.5 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 CEH15819.1 - 9.2e-09 35.7 0.6 9.2e-09 35.7 0.6 4.8 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 CEH15819.1 - 0.0003 20.8 1.0 0.015 15.5 0.1 3.7 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.6 CEH15819.1 - 0.038 14.4 13.0 0.2 12.1 0.5 5.5 7 0 0 7 7 7 0 HEAT repeats Cohesin_HEAT PF12765.7 CEH15819.1 - 0.062 13.6 2.3 6.3 7.2 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion FTO_CTD PF12934.7 CEH15819.1 - 0.13 12.1 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 FTO C-terminal domain HEAT_EZ PF13513.6 CEH15819.1 - 6.8 7.3 16.5 5.1 7.7 0.1 6.1 6 0 0 6 6 6 0 HEAT-like repeat Mitoc_mL59 PF18126.1 CEH15820.1 - 1.1e-21 77.5 6.1 1.9e-21 76.7 6.1 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Pkinase PF00069.25 CEH15821.1 - 2.5e-46 158.2 0.0 5.7e-46 157.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15821.1 - 2.1e-24 86.2 0.0 3.2e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEH15821.1 - 0.054 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEH15821.1 - 0.13 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CEH15821.1 - 0.24 10.7 0.0 0.39 10.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like eIF2A PF08662.11 CEH15823.1 - 9.7e-39 133.3 0.3 1.2e-16 61.1 0.0 4.9 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A YkyB PF14177.6 CEH15823.1 - 0.0012 19.2 1.3 0.29 11.4 0.0 3.0 2 1 1 3 3 3 2 YkyB-like protein RRM_1 PF00076.22 CEH15823.1 - 0.0065 16.3 0.1 0.029 14.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CEH15823.1 - 0.0069 17.2 1.4 1.9 9.5 0.0 4.4 6 0 0 6 6 6 1 WD domain, G-beta repeat DUF2992 PF11208.8 CEH15823.1 - 0.049 13.9 3.5 0.087 13.1 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF445 PF04286.12 CEH15823.1 - 0.21 11.4 2.5 0.31 10.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) OmpH PF03938.14 CEH15823.1 - 0.46 10.8 7.3 0.94 9.8 7.3 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CALCOCO1 PF07888.11 CEH15824.1 - 0.0078 15.1 3.0 0.0085 15.0 3.0 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like RE_Alw26IDE PF09665.10 CEH15824.1 - 0.07 12.3 1.2 0.073 12.2 1.2 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) BRE1 PF08647.11 CEH15824.1 - 0.079 13.0 7.4 0.058 13.5 4.8 1.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase IHABP4_N PF16174.5 CEH15824.1 - 0.2 12.3 9.2 0.25 11.9 9.2 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal HAUS6_N PF14661.6 CEH15824.1 - 1.9 8.0 4.7 2.5 7.6 4.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Homeodomain PF00046.29 CEH15825.1 - 3.2e-13 49.3 0.1 8.2e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEH15825.1 - 2.3e-05 24.2 0.3 4.5e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Helicase_C PF00271.31 CEH15826.1 - 6.6e-17 61.9 0.0 1.5e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 CEH15826.1 - 5e-16 58.9 0.7 1.3e-15 57.6 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 CEH15826.1 - 5.5e-12 45.8 0.1 1e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEH15826.1 - 5.8e-06 26.6 0.1 1.5e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CEH15826.1 - 0.0039 16.6 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 CEH15826.1 - 0.048 12.7 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein K_channel_TID PF07941.11 CEH15826.1 - 0.067 13.7 1.5 0.17 12.4 1.5 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain AAA_16 PF13191.6 CEH15826.1 - 0.12 12.7 0.0 0.48 10.8 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CEH15826.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SARAF PF06682.12 CEH15827.1 - 0.049 13.3 2.0 0.058 13.0 2.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Sec5 PF15469.6 CEH15828.1 - 8.2e-22 77.9 0.1 1.2e-21 77.4 0.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec5 CENP-H PF05837.12 CEH15828.1 - 0.0013 19.1 1.2 3.3 8.1 0.0 2.8 2 1 0 2 2 2 2 Centromere protein H (CENP-H) DUF4835 PF16119.5 CEH15828.1 - 0.0026 16.9 0.0 2.3 7.3 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4835) RuvA_C PF07499.13 CEH15829.1 - 0.027 14.9 0.0 0.1 13.0 0.0 2.0 1 0 0 1 1 1 0 RuvA, C-terminal domain UBA PF00627.31 CEH15829.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain SARAF PF06682.12 CEH15829.1 - 0.11 12.2 2.0 0.17 11.5 2.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis MDMPI_N PF11716.8 CEH15829.1 - 4.5 8.0 8.9 0.14 12.9 1.0 2.2 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain UPF0061 PF02696.14 CEH15830.1 - 3.7e-95 319.5 0.0 7.1e-94 315.2 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family PSD4 PF07631.11 CEH15830.1 - 0.45 11.1 4.4 11 6.6 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1592) Trypan_PARP PF05887.11 CEH15832.1 - 0.042 13.8 0.3 0.042 13.8 0.3 2.6 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 CEH15833.1 - 1.4e-69 234.4 0.0 2.1e-69 233.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15833.1 - 3.6e-47 160.8 0.0 5.8e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH15833.1 - 0.0024 17.2 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEH15833.1 - 0.01 14.6 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Arm PF00514.23 CEH15833.1 - 0.015 15.3 0.2 11 6.3 0.0 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat EutK_C PF16365.5 CEH15833.1 - 0.029 14.4 0.1 12 6.0 0.1 2.8 2 0 0 2 2 2 0 Ethanolamine utilization protein EutK C-terminus Na_H_Exchanger PF00999.21 CEH15835.1 - 6.4e-50 170.0 15.3 8.6e-50 169.6 15.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 CEH15835.1 - 8.2e-05 22.6 0.6 0.00043 20.3 0.0 2.4 2 0 0 2 2 2 1 YrhC-like protein NAD_binding_10 PF13460.6 CEH15836.1 - 5.3e-06 26.5 0.1 9.1e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CEH15836.1 - 0.0051 16.4 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 CEH15836.1 - 0.023 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 CEH15836.1 - 0.046 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 CEH15836.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IGR PF09597.10 CEH15836.1 - 0.074 13.2 0.0 16 5.7 0.0 2.9 3 0 0 3 3 3 0 IGR protein motif NAD_binding_3 PF03447.16 CEH15836.1 - 0.1 13.3 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Zf_RING PF16744.5 CEH15840.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Solute_trans_a PF03619.16 CEH15841.1 - 2e-78 263.6 17.0 2.4e-78 263.3 17.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.11 CEH15841.1 - 0.37 11.0 3.5 0.29 11.3 0.4 2.4 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RRM_1 PF00076.22 CEH15842.1 - 2.7e-05 23.9 0.0 4.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bZIP_2 PF07716.15 CEH15845.1 - 0.0063 16.6 5.1 0.0063 16.6 5.1 2.4 2 0 0 2 2 2 1 Basic region leucine zipper TSC22 PF01166.18 CEH15845.1 - 0.018 15.3 0.1 0.047 14.0 0.1 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 CEH15845.1 - 0.038 13.9 0.2 0.071 13.0 0.2 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 CEH15845.1 - 0.44 11.2 0.0 0.44 11.2 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA PRKG1_interact PF15898.5 CEH15845.1 - 4.8 8.1 14.6 0.38 11.7 1.9 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain PCI PF01399.27 CEH15846.1 - 5.9e-18 65.3 0.3 1.4e-17 64.1 0.3 1.7 1 0 0 1 1 1 1 PCI domain FeoC PF09012.10 CEH15846.1 - 0.0018 18.3 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator TPR_10 PF13374.6 CEH15846.1 - 0.018 14.9 1.0 0.83 9.6 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3384 PF11864.8 CEH15846.1 - 0.082 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) zf-CCCH_4 PF18044.1 CEH15847.1 - 2.3e-12 46.4 17.8 4.9e-07 29.4 5.3 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEH15847.1 - 1.7e-08 34.3 15.5 1.5e-05 24.9 5.2 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CEH15847.1 - 3.4e-08 33.2 13.8 0.00041 20.2 4.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CEH15847.1 - 1.5e-07 31.6 22.2 7.4e-06 26.2 8.2 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEH15847.1 - 9.5e-05 23.1 0.1 9.5e-05 23.1 0.1 3.1 3 0 0 3 3 3 1 Torus domain Ank_2 PF12796.7 CEH15847.1 - 0.00016 22.2 0.1 0.00029 21.4 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEH15847.1 - 0.0024 18.1 0.0 0.0048 17.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEH15847.1 - 0.0032 18.0 0.0 0.0097 16.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEH15847.1 - 0.021 15.3 0.0 0.08 13.5 0.0 2.0 2 0 0 2 2 1 0 Ankyrin repeat Ank PF00023.30 CEH15847.1 - 0.038 14.4 0.0 0.098 13.2 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat HMG14_17 PF01101.18 CEH15847.1 - 3.4 8.7 16.9 0.095 13.7 7.5 2.7 2 1 0 2 2 2 0 HMG14 and HMG17 WD40 PF00400.32 CEH15848.1 - 3.9e-16 59.1 23.7 0.0019 19.0 0.2 7.4 6 1 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 CEH15848.1 - 0.024 13.2 1.0 1.2 7.6 0.0 2.9 2 1 1 3 3 3 0 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 CEH15848.1 - 0.074 13.4 0.0 2 8.8 0.0 3.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CEH15848.1 - 0.11 11.2 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like BUD22 PF09073.10 CEH15848.1 - 2.1 7.6 17.2 3.8 6.7 17.2 1.5 1 0 0 1 1 1 0 BUD22 Pyr_redox_3 PF13738.6 CEH15853.1 - 3.1e-11 43.1 0.0 4.1e-10 39.4 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEH15853.1 - 1.5e-09 37.5 0.0 2.4e-06 27.0 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 CEH15853.1 - 4.7e-08 31.9 0.1 1.6e-07 30.2 0.3 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 CEH15853.1 - 1.4e-07 31.0 0.0 5.2e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CEH15853.1 - 5.4e-07 29.8 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEH15853.1 - 0.011 15.4 0.0 0.042 13.4 0.0 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CEH15853.1 - 0.026 13.6 0.1 2.2 7.2 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 CEH15853.1 - 0.087 12.8 0.0 2.9 7.9 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding RPAP3_C PF13877.6 CEH15854.1 - 1.1e-10 41.9 0.4 3.9e-10 40.1 0.4 1.7 1 1 0 1 1 1 1 Potential Monad-binding region of RPAP3 FHA PF00498.26 CEH15855.1 - 0.0085 16.4 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain SCF PF02404.15 CEH15856.1 - 0.071 12.4 0.2 0.077 12.3 0.2 1.1 1 0 0 1 1 1 0 Stem cell factor Dicer_dimer PF03368.14 CEH15857.1 - 0.0076 16.4 1.1 4.7 7.4 0.1 2.6 1 1 1 2 2 2 2 Dicer dimerisation domain DEAD PF00270.29 CEH15858.1 - 9.6e-34 116.7 0.0 1.5e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH15858.1 - 3.4e-25 88.5 0.1 7.9e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CEH15858.1 - 0.0097 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 CEH15858.1 - 0.034 13.5 0.0 0.092 12.1 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit TPR_19 PF14559.6 CEH15859.1 - 0.00074 20.0 1.6 0.0017 18.8 1.6 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH15859.1 - 0.02 15.1 3.4 0.03 14.6 3.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SQS_PSY PF00494.19 CEH15860.1 - 2e-34 119.3 0.0 5.5e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Squalene/phytoene synthase NAD_binding_8 PF13450.6 CEH15861.1 - 1e-09 38.4 0.3 3.6e-09 36.7 0.3 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CEH15861.1 - 7.8e-08 32.0 0.0 1.6e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 CEH15861.1 - 7.3e-05 22.5 0.3 7.3e-05 22.5 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEH15861.1 - 0.00059 19.2 0.4 0.0011 18.3 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEH15861.1 - 0.0014 17.9 0.3 0.0025 17.1 0.3 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 CEH15861.1 - 0.0048 16.9 0.4 0.0097 15.9 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CEH15861.1 - 0.05 12.7 0.6 0.083 12.0 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 CEH15861.1 - 0.053 12.9 1.3 0.075 12.4 0.5 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 CEH15861.1 - 0.072 13.7 0.3 0.26 11.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.21 CEH15862.1 - 2.1e-34 119.1 0.1 7e-33 114.1 0.1 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family DDHD PF02862.17 CEH15863.1 - 4e-27 95.8 2.0 2.6e-25 89.9 0.0 3.1 2 2 0 2 2 2 1 DDHD domain Abhydrolase_6 PF12697.7 CEH15863.1 - 0.013 16.1 1.2 0.058 14.0 0.1 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Cellulase PF00150.18 CEH15864.1 - 1.9e-08 34.1 0.4 2.6e-07 30.4 0.4 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Got1 PF04178.12 CEH15865.1 - 8.9e-20 71.2 19.6 1.2e-19 70.7 19.6 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3566 PF12089.8 CEH15865.1 - 1.9 8.8 15.5 2.2 8.6 14.2 1.7 1 1 1 2 2 2 0 Transmembrane domain of unknown function (DUF3566) Stevor PF17410.2 CEH15865.1 - 4.6 6.7 5.8 6.3 6.3 5.8 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SEN1_N PF12726.7 CEH15866.1 - 3e-58 197.7 0.0 7.2e-48 163.4 0.0 3.1 2 1 0 2 2 2 2 SEN1 N terminal AAA_11 PF13086.6 CEH15866.1 - 9e-46 156.8 2.8 3.6e-36 125.3 0.4 2.8 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.6 CEH15866.1 - 3.8e-24 85.4 0.1 5.1e-18 65.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CEH15866.1 - 8.5e-09 35.4 0.9 2.2e-08 34.0 0.9 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH15866.1 - 6.5e-07 29.8 1.8 1.4e-06 28.7 0.4 2.4 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CEH15866.1 - 3.3e-05 23.7 0.3 0.015 15.1 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CEH15866.1 - 0.014 15.0 0.0 0.55 9.7 0.1 2.3 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 CEH15866.1 - 0.026 13.6 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 CEH15866.1 - 0.072 13.5 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CEH15866.1 - 0.16 11.1 0.2 0.73 9.0 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CEH15866.1 - 0.17 12.1 0.1 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain SIN1 PF05422.12 CEH15866.1 - 1.1 9.8 4.4 0.76 10.3 0.9 2.5 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) Melibiase_2 PF16499.5 CEH15867.1 - 1.5e-35 122.8 0.9 2.5e-35 122.0 0.9 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CEH15867.1 - 8.8e-08 32.1 0.1 2.4e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CEH15867.1 - 0.0062 15.5 0.0 0.021 13.8 0.0 1.9 2 0 0 2 2 2 1 Melibiase CBM_6 PF03422.15 CEH15867.1 - 0.075 13.3 0.6 0.18 12.1 0.6 1.7 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) Mago_nashi PF02792.14 CEH15868.1 - 9.2e-40 136.1 0.0 1e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.20 CEH15869.1 - 1.4e-112 376.9 0.0 2e-112 376.4 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CEH15869.1 - 5.1e-52 176.0 0.6 1.1e-51 175.0 0.6 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CEH15869.1 - 1.8e-29 102.2 0.0 6.1e-29 100.5 0.0 2.0 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CEH15869.1 - 1.2e-19 70.5 3.9 1.1e-10 41.8 0.1 6.0 3 2 4 7 7 7 5 HEAT repeats Cnd1 PF12717.7 CEH15869.1 - 2.3e-08 34.2 5.4 0.0063 16.6 0.2 3.9 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEH15869.1 - 1.4e-05 25.0 6.5 2.3 8.7 0.3 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_PBS PF03130.16 CEH15869.1 - 4.2 8.3 17.3 1.7 9.5 0.3 6.1 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat PPR_2 PF13041.6 CEH15870.1 - 0.0011 19.1 0.1 2.6 8.3 0.1 2.7 2 0 0 2 2 2 2 PPR repeat family GATA PF00320.27 CEH15871.1 - 2e-13 49.7 3.3 4.4e-13 48.6 3.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.7 CEH15871.1 - 0.14 12.2 0.2 0.32 11.1 0.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon CtaG_Cox11 PF04442.14 CEH15872.1 - 3.7e-55 186.1 0.0 4.6e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DnaJ_CXXCXGXG PF00684.19 CEH15873.1 - 0.012 15.9 10.2 0.19 12.1 3.2 2.5 2 0 0 2 2 2 0 DnaJ central domain DUF5351 PF17302.2 CEH15873.1 - 0.023 14.8 2.4 0.023 14.8 2.4 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5351) SRP_SPB PF02978.19 CEH15875.1 - 0.14 12.8 1.2 0.46 11.1 1.2 1.9 1 0 0 1 1 1 0 Signal peptide binding domain Mating_N PF12731.7 CEH15881.1 - 0.0059 16.7 0.1 0.0072 16.4 0.1 1.1 1 0 0 1 1 1 1 Mating-type protein beta 1 HLH PF00010.26 CEH15882.1 - 5.2e-09 35.9 0.0 1.3e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Fcf2 PF08698.11 CEH15883.1 - 3.6e-21 75.4 0.0 4.1e-19 68.8 0.0 2.6 2 0 0 2 2 2 2 Fcf2 pre-rRNA processing MFS_1 PF07690.16 CEH15885.1 - 1.3e-23 83.5 37.1 1.8e-22 79.8 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH15885.1 - 9.5e-09 34.6 0.0 9.5e-09 34.6 0.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1295 PF06966.12 CEH15887.1 - 6.4e-43 147.0 0.4 6.1e-42 143.7 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 CEH15887.1 - 0.0066 16.9 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PRIMA1 PF16101.5 CEH15887.1 - 0.055 13.5 3.2 0.1 12.6 3.2 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 adh_short_C2 PF13561.6 CEH15888.1 - 6.3e-49 166.6 2.7 2.2e-46 158.3 2.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH15888.1 - 1.1e-48 165.3 1.3 1.4e-48 165.0 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH15888.1 - 7.5e-11 42.3 1.2 1.3e-10 41.5 1.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CEH15888.1 - 0.12 12.2 0.6 0.19 11.6 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4430 PF14478.6 CEH15891.1 - 0.0041 17.7 0.1 0.0082 16.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) Mucin PF01456.17 CEH15891.1 - 0.14 12.1 49.6 0.064 13.2 15.4 2.9 3 0 0 3 3 3 0 Mucin-like glycoprotein MGC-24 PF05283.11 CEH15891.1 - 2.8 8.4 24.5 0.74 10.3 7.7 2.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Hist_deacetyl PF00850.19 CEH15892.1 - 4e-43 148.0 0.3 7.9e-43 147.1 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Gryzun PF07919.12 CEH15893.1 - 0.069 11.9 2.6 2.7 6.7 0.3 2.1 2 0 0 2 2 2 0 Gryzun, putative trafficking through Golgi DUF4242 PF14026.6 CEH15894.1 - 0.14 12.4 0.1 0.2 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Glyco_hydro_30 PF02055.16 CEH15895.1 - 0.14 11.1 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain RT_RNaseH PF17917.1 CEH15898.1 - 2e-67 224.1 0.4 1e-32 112.5 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEH15898.1 - 2.1e-55 184.9 3.9 2e-12 47.0 0.0 4.4 4 0 0 4 4 4 4 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEH15898.1 - 1e-53 182.1 0.1 6.4e-28 97.8 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEH15898.1 - 3.4e-12 46.3 0.0 7.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CEH15898.1 - 5.9e-11 42.1 0.0 1.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CEH15898.1 - 1.3e-06 28.6 0.0 3.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 CEH15898.1 - 0.025 15.2 0.0 0.06 14.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Retrotran_gag_2 PF14223.6 CEH15898.1 - 0.04 13.6 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type 7TM_GPCR_Srsx PF10320.9 CEH15898.1 - 0.079 12.3 0.1 6.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx Staufen_C PF16482.5 CEH15898.1 - 0.13 12.5 0.0 41 4.4 0.0 3.6 5 0 0 5 5 5 0 Staufen C-terminal domain GIIM PF08388.11 CEH15898.1 - 0.4 10.8 2.1 2.4e+02 1.9 0.0 4.3 4 0 0 4 4 4 0 Group II intron, maturase-specific domain zf-CCHC_5 PF14787.6 CEH15899.1 - 6.9e-06 25.7 1.0 6.9e-06 25.7 1.0 1.8 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 CEH15899.1 - 0.00045 20.2 0.9 0.001 19.0 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CEH15899.1 - 0.0092 16.2 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 CEH15899.1 - 0.049 13.5 0.7 0.083 12.7 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 CEH15899.1 - 0.058 13.4 0.6 0.16 12.0 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 CEH15899.1 - 5.1 7.0 6.8 1.8 8.5 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle Cys_Met_Meta_PP PF01053.20 CEH15901.1 - 3e-26 91.9 0.0 1e-19 70.4 0.0 2.3 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Nas2_N PF18265.1 CEH15901.1 - 7.2e-20 70.7 0.1 1.6e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 Nas2 N_terminal domain Aminotran_1_2 PF00155.21 CEH15901.1 - 0.0012 18.0 0.0 0.0029 16.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II adh_short PF00106.25 CEH15902.1 - 1e-24 87.1 0.0 6.2e-20 71.5 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEH15902.1 - 8.7e-20 71.3 0.1 1.4e-16 60.7 0.2 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH15902.1 - 1.5e-09 38.0 0.3 2.7e-09 37.2 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEH15902.1 - 7.8e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CEH15902.1 - 0.0018 17.7 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 CEH15902.1 - 0.034 14.4 0.2 0.086 13.1 0.2 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_transf_9 PF01075.17 CEH15902.1 - 0.077 12.3 0.8 0.16 11.2 0.8 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) MBOAT PF03062.19 CEH15903.1 - 6.7e-38 130.9 5.6 6.7e-38 130.9 5.6 2.3 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CEH15903.1 - 0.00088 19.5 1.4 0.0023 18.1 1.4 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ribosomal_L24e PF01246.20 CEH15904.1 - 6.4e-19 68.0 4.6 6.4e-19 68.0 4.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e HAGH_C PF16123.5 CEH15904.1 - 0.0067 16.9 1.6 0.0067 16.9 1.6 1.9 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus CCDC71L PF15374.6 CEH15904.1 - 0.85 8.8 12.6 1.1 8.4 12.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L ATP-synt_ab PF00006.25 CEH15905.1 - 1.7e-72 243.6 0.0 2.8e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CEH15905.1 - 6e-40 136.5 0.0 1e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CEH15905.1 - 4.1e-20 72.1 1.6 9.4e-20 70.9 1.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CEH15905.1 - 0.024 14.8 0.5 0.053 13.7 0.5 1.6 1 0 0 1 1 1 0 HAS barrel domain TniB PF05621.11 CEH15905.1 - 0.063 12.7 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein TPR_1 PF00515.28 CEH15906.1 - 9.7e-27 91.7 15.4 7.4e-05 22.4 0.0 6.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 CEH15906.1 - 8.1e-25 84.9 17.5 0.00047 20.1 0.0 7.7 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 CEH15906.1 - 1.3e-20 71.8 0.4 3e-05 23.9 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat ANAPC8 PF04049.13 CEH15906.1 - 4.1e-14 52.8 2.5 4.9e-07 29.9 0.0 3.0 3 0 0 3 3 3 2 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 CEH15906.1 - 2.4e-13 49.7 14.6 2.2e-06 28.0 0.8 7.9 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEH15906.1 - 5.9e-12 45.1 9.2 0.00014 21.4 0.0 5.7 5 1 1 6 6 6 2 TPR repeat TPR_7 PF13176.6 CEH15906.1 - 3.2e-11 42.4 5.2 0.011 15.7 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEH15906.1 - 3.7e-11 43.5 21.4 3.6e-05 24.3 1.7 7.9 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEH15906.1 - 6.8e-11 41.8 3.6 0.43 11.1 0.1 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEH15906.1 - 6.8e-09 35.9 12.8 5.8e-05 23.3 0.6 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 CEH15906.1 - 3.7e-08 32.9 1.2 4.2e-06 26.2 0.3 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEH15906.1 - 5.2e-07 30.1 8.1 0.0024 18.3 0.1 5.6 3 1 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH15906.1 - 1.2e-06 28.6 15.6 0.0043 17.2 1.2 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CEH15906.1 - 1.8e-05 24.8 14.3 0.00024 21.2 2.1 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEH15906.1 - 7.5e-05 22.5 9.6 0.25 11.3 0.2 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat ChAPs PF09295.10 CEH15906.1 - 0.00038 19.6 0.0 0.01 14.9 0.0 2.8 3 1 1 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CEH15906.1 - 0.0019 18.7 5.9 2.6 8.8 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat SNAP PF14938.6 CEH15906.1 - 0.0021 17.5 1.2 0.006 16.0 0.1 2.2 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP BTAD PF03704.17 CEH15906.1 - 0.079 13.4 8.4 0.25 11.8 1.1 3.0 3 0 0 3 3 3 0 Bacterial transcriptional activator domain AMP-binding PF00501.28 CEH15907.1 - 5e-75 252.7 0.0 7e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEH15907.1 - 1.1e-19 71.2 0.3 2.4e-19 70.1 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CEH15907.1 - 1.9e-05 24.5 0.1 1.9e-05 24.5 0.1 2.1 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus BAG PF02179.16 CEH15911.1 - 3.2e-17 62.7 0.1 4.4e-17 62.3 0.1 1.2 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 CEH15911.1 - 1.4e-07 31.1 0.0 2.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Cyto_heme_lyase PF01265.17 CEH15912.1 - 7.7e-76 255.5 17.9 3.1e-60 204.3 6.3 2.9 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase Sortilin-Vps10 PF15902.5 CEH15914.1 - 2.8e-263 873.5 0.0 2.7e-148 494.5 0.0 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CEH15914.1 - 3.1e-85 284.8 9.2 3.5e-45 154.4 3.1 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal CHB_HEX_C PF03174.13 CEH15914.1 - 4.7e-05 23.3 1.7 0.16 12.0 0.0 5.4 5 2 1 6 6 6 1 Chitobiase/beta-hexosaminidase C-terminal domain BNR PF02012.20 CEH15914.1 - 0.029 14.3 53.2 0.23 11.6 0.9 11.7 13 0 0 13 13 13 0 BNR/Asp-box repeat PSII_BNR PF14870.6 CEH15914.1 - 0.25 10.6 6.3 22 4.2 0.0 5.4 4 3 1 6 6 6 0 Photosynthesis system II assembly factor YCF48 PRKG1_interact PF15898.5 CEH15915.1 - 0.031 15.2 1.0 0.031 15.2 1.0 11.4 3 3 7 10 10 10 0 cGMP-dependent protein kinase interacting domain Pox_A_type_inc PF04508.12 CEH15915.1 - 0.12 12.3 12.6 1.6 8.7 0.1 5.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat SH3_1 PF00018.28 CEH15916.1 - 7.2e-41 137.6 6.7 2.5e-15 55.8 0.1 4.1 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 CEH15916.1 - 1.2e-40 137.1 8.4 7e-15 54.6 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 CEH15916.1 - 8e-32 108.9 0.0 1.5e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 CEH15916.1 - 7.2e-22 76.8 0.0 1.5e-05 24.6 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain DUF1720 PF08226.11 CEH15916.1 - 1.4e-05 25.4 34.9 1.4e-05 25.4 34.9 5.2 2 1 2 4 4 4 2 Domain of unknown function (DUF1720) SH3_10 PF17902.1 CEH15916.1 - 1.9e-05 24.6 0.1 0.00069 19.6 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SAM_4 PF18017.1 CEH15916.1 - 7.8e-05 22.6 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 CEH15916.1 - 0.00022 21.4 3.4 0.003 17.8 0.3 3.1 4 0 0 4 4 4 1 Bacterial SH3 domain zf-RING_UBOX PF13445.6 CEH15917.1 - 2e-07 30.9 4.8 2.6e-07 30.5 3.4 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CEH15917.1 - 2.4e-07 31.0 8.2 5.4e-07 29.8 7.9 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEH15917.1 - 2.5e-06 27.1 1.2 2.5e-06 27.1 1.2 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 CEH15917.1 - 3.2e-06 27.0 8.4 6.3e-06 26.1 8.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Spc7 PF08317.11 CEH15917.1 - 4.3e-06 25.9 22.6 4.3e-06 25.9 22.6 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein zf-C3HC4 PF00097.25 CEH15917.1 - 7.8e-05 22.5 8.0 0.00017 21.4 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEH15917.1 - 7.8e-05 22.9 6.9 0.00024 21.3 6.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEH15917.1 - 0.00045 20.0 1.9 0.0013 18.5 1.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BBP1_C PF15272.6 CEH15917.1 - 0.00056 19.8 6.5 0.00056 19.8 6.5 2.4 1 1 0 2 2 2 1 Spindle pole body component BBP1, C-terminal zf-C3HC4_4 PF15227.6 CEH15917.1 - 0.0012 18.9 5.7 0.0037 17.4 5.7 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CEH15917.1 - 0.0029 17.8 0.9 0.0029 17.8 0.9 1.9 2 0 0 2 2 2 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CEH15917.1 - 0.072 13.1 4.6 0.15 12.1 4.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MAD PF05557.13 CEH15917.1 - 1 7.6 35.5 0.81 8.0 34.3 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein Zn_ribbon_17 PF17120.5 CEH15917.1 - 2.6 7.7 9.7 6.6 6.4 9.7 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FlaC_arch PF05377.11 CEH15917.1 - 6.2 7.3 6.9 65 4.0 0.8 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Hira PF07569.11 CEH15918.1 - 3.2e-32 112.1 0.1 6e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 CEH15918.1 - 2.9e-20 72.2 23.6 4.4e-07 30.5 0.1 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH15918.1 - 5e-08 33.1 0.6 0.02 15.2 0.0 5.1 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 CEH15918.1 - 0.00012 21.9 0.4 0.00036 20.3 0.4 1.9 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 CEH15918.1 - 0.046 12.7 0.0 27 3.6 0.0 3.3 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CEH15918.1 - 0.047 13.7 2.6 12 5.9 0.4 4.2 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat Vezatin PF12632.7 CEH15919.1 - 3.5e-19 69.2 0.2 9.7e-13 48.1 0.1 3.4 2 1 0 2 2 2 2 Mysoin-binding motif of peroxisomes DUF2306 PF10067.9 CEH15920.1 - 1.1e-08 35.4 13.2 1.1e-08 35.4 13.2 2.1 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) Rnk_N PF14760.6 CEH15921.1 - 0.0014 19.1 0.2 0.4 11.2 0.1 3.1 2 0 0 2 2 2 2 Rnk N-terminus Glyco_hydro_18 PF00704.28 CEH15922.1 - 2.3e-10 40.7 0.0 2.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1884 PF08967.10 CEH15922.1 - 0.025 14.8 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1884) Inhibitor_Mig-6 PF11555.8 CEH15922.1 - 0.27 11.4 2.2 4.2 7.5 0.2 2.6 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Ribosomal_L27A PF00828.19 CEH15923.1 - 2.2e-21 76.8 0.0 3.3e-21 76.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 CEH15923.1 - 0.21 11.7 0.7 3.8 7.6 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5026) zf-RING_5 PF14634.6 CEH15924.1 - 4.1e-06 26.6 8.3 7.8e-06 25.8 3.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zinc_ribbon_10 PF10058.9 CEH15924.1 - 0.032 14.0 0.7 0.06 13.1 0.7 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein POTRA PF07244.15 CEH15924.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.3 1 0 0 1 1 1 0 Surface antigen variable number repeat zf-piccolo PF05715.13 CEH15924.1 - 0.15 12.2 3.3 0.33 11.1 3.3 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_6 PF14835.6 CEH15924.1 - 0.39 10.6 2.4 0.27 11.1 0.3 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CEH15924.1 - 1.1 9.2 8.1 0.48 10.3 3.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CEH15924.1 - 7.2 6.6 7.4 1.4 8.8 0.2 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) THOC7 PF05615.13 CEH15925.1 - 1.2e-07 32.1 2.3 2.2e-07 31.2 2.3 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 APG6_N PF17675.1 CEH15925.1 - 0.024 15.2 1.3 0.045 14.3 1.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region MCD_N PF17408.2 CEH15925.1 - 0.055 13.6 0.4 0.13 12.4 0.4 1.8 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain zf-C4H2 PF10146.9 CEH15925.1 - 0.057 13.7 0.1 0.081 13.2 0.1 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DNA_photolyase PF00875.18 CEH15925.1 - 0.092 12.7 1.4 4 7.4 0.2 2.3 1 1 1 2 2 2 0 DNA photolyase ATF7IP_BD PF16788.5 CEH15925.1 - 0.12 12.5 1.9 0.11 12.6 0.2 1.9 2 0 0 2 2 2 0 ATF-interacting protein binding domain MUG113 PF13455.6 CEH15926.1 - 2.6e-11 44.0 0.0 5.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 CEH15926.1 - 3.4e-08 34.0 0.1 1.4e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 T5orf172 domain SmpA_OmlA PF04355.13 CEH15926.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 SmpA / OmlA family zf-primase PF09329.11 CEH15926.1 - 0.18 11.6 2.8 0.98 9.3 0.4 2.4 2 0 0 2 2 2 0 Primase zinc finger SNRNP27 PF08648.12 CEH15927.1 - 1.1e-29 102.3 1.1 2.7e-29 101.0 1.1 1.8 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins PIF1 PF05970.14 CEH15928.1 - 2e-55 188.5 0.2 8.8e-48 163.3 0.2 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CEH15928.1 - 1.3e-22 80.4 0.1 2.3e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH15928.1 - 1.1e-09 38.8 0.0 2.6e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEH15928.1 - 9.3e-06 26.0 0.0 2.8e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CEH15928.1 - 0.0002 20.9 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 CEH15928.1 - 0.00023 20.9 0.1 0.00064 19.5 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 CEH15928.1 - 0.00053 18.1 1.1 0.016 13.2 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.6 CEH15928.1 - 0.00079 19.8 0.0 0.0027 18.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CEH15928.1 - 0.0078 16.2 0.2 0.18 11.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 CEH15928.1 - 0.012 14.8 0.9 0.23 10.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CEH15928.1 - 0.027 13.9 0.1 0.29 10.6 0.0 2.3 2 1 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 CEH15928.1 - 0.036 14.0 0.1 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 CEH15928.1 - 0.045 14.3 0.0 0.22 12.1 0.0 2.2 1 0 0 1 1 1 0 ABC transporter SH3_13 PF18335.1 CEH15928.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Viral_helicase1 PF01443.18 CEH15928.1 - 0.063 13.0 0.4 9.3 5.9 0.1 3.1 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CEH15928.1 - 0.064 13.0 2.7 0.38 10.5 0.0 2.9 2 1 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 CEH15928.1 - 0.069 12.0 0.1 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 CEH15928.1 - 0.079 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 CEH15928.1 - 0.1 13.1 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 CEH15930.1 - 5.3e-38 130.9 0.0 1.4e-37 129.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH15930.1 - 1.3e-14 54.1 0.0 2.4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEH15930.1 - 0.00046 20.2 0.1 0.0038 17.2 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CEH15930.1 - 0.003 17.2 0.0 0.0072 15.9 0.0 1.6 1 0 0 1 1 1 1 RIO1 family CENP-T_C PF15511.6 CEH15934.1 - 1.7e-08 34.5 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CEH15934.1 - 0.00012 22.3 0.0 0.00019 21.6 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CEH15934.1 - 0.00039 20.5 0.1 0.00056 20.0 0.0 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CEH15934.1 - 0.0015 18.8 0.0 0.002 18.4 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 CEH15934.1 - 0.002 18.5 0.0 0.0023 18.3 0.0 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CEH15934.1 - 0.17 12.0 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MS_channel PF00924.18 CEH15935.1 - 1.2e-16 60.9 2.0 1.2e-16 60.9 2.0 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 CEH15935.1 - 0.00011 21.4 0.2 0.00025 20.4 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CEH15935.1 - 0.00028 20.6 0.0 0.00072 19.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CEH15935.1 - 0.024 14.1 0.5 0.056 13.0 0.5 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 CEH15935.1 - 0.05 14.1 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair PBP1_TM PF14812.6 CEH15935.1 - 0.12 12.8 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LIM PF00412.22 CEH15937.1 - 6e-20 71.2 22.7 1.5e-12 47.6 2.8 4.6 5 0 0 5 5 5 3 LIM domain MPTase-PolyVal PF18818.1 CEH15937.1 - 0.015 15.3 0.2 0.058 13.5 0.1 1.8 2 0 0 2 2 2 0 Metallopeptidase superfamily domain zf-C2H2 PF00096.26 CEH15937.1 - 7.5 7.2 9.5 10 6.8 0.4 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type RhoGAP PF00620.27 CEH15938.1 - 6.1e-37 126.8 0.1 9.8e-37 126.1 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain Ribophorin_II PF05817.14 CEH15940.1 - 1.5e-13 50.2 0.0 2e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II ACTH_assoc PF16102.5 CEH15940.1 - 0.3 11.9 2.1 1.4 9.8 0.4 2.7 2 0 0 2 2 2 0 ACTH-associated domain Sua5_yciO_yrdC PF01300.18 CEH15941.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Telomere recombination Nup35_RRM_2 PF14605.6 CEH15941.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Methyltr_RsmB-F PF01189.17 CEH15942.1 - 2.5e-35 121.9 0.0 4.6e-32 111.3 0.0 2.9 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F RPAP1_N PF08621.10 CEH15944.1 - 0.47 10.3 1.8 0.4 10.5 0.3 1.6 2 0 0 2 2 2 0 RPAP1-like, N-terminal DUF4448 PF14610.6 CEH15945.1 - 0.00052 19.9 0.0 0.00099 18.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 CEH15945.1 - 0.02 15.6 0.5 0.037 14.8 0.5 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MFS_1 PF07690.16 CEH15946.1 - 2e-29 102.6 25.6 3e-29 102.1 25.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1003 PF06210.11 CEH15946.1 - 0.028 14.5 0.2 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) MRVI1 PF05781.12 CEH15946.1 - 0.23 10.1 0.3 0.44 9.2 0.3 1.4 1 0 0 1 1 1 0 MRVI1 protein TPR_1 PF00515.28 CEH15947.1 - 2.4e-25 87.2 20.1 0.00011 21.8 0.1 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 CEH15947.1 - 6.4e-25 85.2 20.2 0.0013 18.7 0.5 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.31 CEH15947.1 - 9.3e-21 73.7 1.3 9.3e-21 73.7 1.3 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 CEH15947.1 - 1.9e-18 66.7 22.3 0.00062 20.2 0.1 6.3 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEH15947.1 - 1.3e-15 57.7 29.4 1.4e-07 32.0 1.2 7.4 4 3 3 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 CEH15947.1 - 9.9e-13 47.2 17.9 1.7 9.0 0.4 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 CEH15947.1 - 2.1e-12 47.1 23.1 0.00059 20.1 0.7 6.6 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CEH15947.1 - 3.7e-12 46.0 21.6 0.0065 17.2 0.1 7.9 5 3 4 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH15947.1 - 2.5e-11 43.6 14.3 0.00023 21.3 1.4 4.0 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CEH15947.1 - 3.8e-10 39.3 17.6 1e-06 28.3 0.3 7.0 6 2 2 8 8 8 2 TPR repeat TPR_9 PF13371.6 CEH15947.1 - 1.6e-09 37.8 9.9 0.012 15.8 0.1 4.3 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 CEH15947.1 - 2.1e-09 36.7 13.5 0.025 14.6 0.0 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEH15947.1 - 7.7e-09 35.3 12.1 0.053 13.9 0.3 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 CEH15947.1 - 1.6e-08 34.6 13.1 0.15 12.8 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEH15947.1 - 0.00098 19.1 12.2 0.062 13.4 0.3 5.0 6 1 1 7 7 5 2 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 CEH15947.1 - 0.002 18.2 10.3 0.0058 16.7 0.4 4.0 4 0 0 4 4 4 1 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 CEH15947.1 - 0.006 16.0 7.3 0.023 14.1 0.2 3.7 4 0 0 4 4 4 1 SHNi-TPR MIT PF04212.18 CEH15947.1 - 0.006 16.6 19.5 1.2 9.3 0.2 5.2 3 1 2 5 5 5 2 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 CEH15947.1 - 0.043 12.8 0.4 1.5 7.8 0.1 2.6 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4363 PF14276.6 CEH15947.1 - 0.25 11.5 7.0 1.3 9.2 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) SCAB_CC PF16712.5 CEH15947.1 - 0.58 10.0 4.3 0.29 11.0 0.2 2.4 3 1 0 3 3 3 0 Coiled-coil regions of plant-specific actin-binding protein HSCB_C PF07743.13 CEH15947.1 - 1.1 9.8 10.0 8.9 6.9 0.5 4.1 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain TPR_10 PF13374.6 CEH15947.1 - 3.4 7.7 22.9 13 5.8 0.1 6.9 7 1 1 8 8 8 0 Tetratricopeptide repeat HIP1_clath_bdg PF16515.5 CEH15947.1 - 4.5 7.9 9.3 13 6.5 0.1 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Adenylsucc_synt PF00709.21 CEH15948.1 - 3.3e-174 579.7 0.0 3.8e-174 579.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MA3 PF02847.17 CEH15949.1 - 6.5e-13 48.6 0.0 1.4e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 CEH15949.1 - 3.8e-11 43.0 0.0 7.4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain Abhydrolase_1 PF00561.20 CEH15950.1 - 0.00034 20.3 0.4 0.00053 19.7 0.4 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH15950.1 - 0.00038 21.1 0.1 0.00049 20.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 CEH15950.1 - 0.0042 16.6 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) BAAT_C PF08840.11 CEH15950.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal NAD_binding_2 PF03446.15 CEH15951.1 - 2.9e-29 102.3 0.0 5.5e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CEH15951.1 - 7.1e-29 100.5 0.0 1.2e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IML1 PF12257.8 CEH15952.1 - 3.8e-110 367.5 0.0 5.4e-110 367.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 CEH15952.1 - 5.1e-19 68.1 0.2 1.1e-18 67.1 0.2 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Thioesterase PF00975.20 CEH15952.1 - 0.066 13.3 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Thioesterase domain ATP_transf PF09830.9 CEH15953.1 - 1.2e-17 63.8 0.0 2.8e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase Sec15 PF04091.12 CEH15954.1 - 5.5e-85 285.5 0.0 9.7e-85 284.7 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 CEH15954.1 - 9.5e-07 28.8 0.4 1.9e-05 24.6 0.1 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 CEH15954.1 - 8.9e-05 22.6 0.6 8.9e-05 22.6 0.6 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 CEH15954.1 - 0.0004 20.6 3.6 0.00043 20.5 0.2 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 CEH15954.1 - 0.0004 20.4 0.7 0.021 14.9 0.0 3.1 2 1 1 3 3 3 1 Vps51/Vps67 DUF2258 PF10015.9 CEH15954.1 - 0.0098 16.0 0.6 0.063 13.4 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2258) ATG16 PF08614.11 CEH15954.1 - 0.062 13.5 1.2 0.2 11.8 1.2 1.9 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 CEH15954.1 - 0.11 12.9 0.8 3.9 8.0 0.0 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FAM194 PF14977.6 CEH15954.1 - 0.19 11.0 0.0 0.5 9.6 0.0 1.7 1 0 0 1 1 1 0 FAM194 protein Vps53_N PF04100.12 CEH15954.1 - 0.24 10.3 2.8 0.24 10.3 0.1 2.3 3 0 0 3 3 3 0 Vps53-like, N-terminal ArfGap PF01412.18 CEH15955.1 - 1.1e-31 109.3 0.0 2.3e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf tRNA-synt_1e PF01406.19 CEH15956.1 - 7.2e-123 409.7 0.0 1.7e-122 408.5 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CEH15956.1 - 3.6e-09 35.8 0.2 4.3e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 CEH15956.1 - 0.00068 20.1 0.8 0.0036 17.8 0.0 2.7 3 0 0 3 3 3 1 DALR domain tRNA-synt_1 PF00133.22 CEH15956.1 - 0.0052 15.1 0.2 0.097 10.9 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 CEH15956.1 - 0.088 11.7 0.9 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain WD40 PF00400.32 CEH15957.1 - 3.2e-06 27.8 8.0 0.57 11.2 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Fungal_trans PF04082.18 CEH15958.1 - 9.7e-13 47.7 0.1 1.5e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH15958.1 - 0.00069 19.7 14.9 0.0012 18.9 14.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERCC3_RAD25_C PF16203.5 CEH15960.1 - 2e-120 400.6 0.1 3.5e-120 399.8 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CEH15960.1 - 8.2e-35 119.7 0.0 1.5e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH15960.1 - 4.8e-18 65.7 0.0 8.8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEH15960.1 - 4.4e-13 49.6 0.2 1.2e-12 48.1 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CEH15960.1 - 7e-09 34.9 0.0 8.6e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CEH15960.1 - 3.8e-06 26.8 0.8 5.1e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase GST_N PF02798.20 CEH15961.1 - 3.8e-13 49.6 0.0 6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CEH15961.1 - 1.3e-09 38.3 0.0 2.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEH15961.1 - 8.1e-08 32.5 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PTS_EIIC_2 PF13303.6 CEH15961.1 - 0.083 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC UCH PF00443.29 CEH15962.1 - 7.8e-60 202.5 0.0 1.2e-59 202.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEH15962.1 - 5.1e-19 69.0 0.0 1.1e-15 58.1 0.0 2.2 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 CEH15962.1 - 4.7e-05 23.5 0.7 8.9e-05 22.7 0.7 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain zf-MIZ PF02891.20 CEH15962.1 - 0.001 18.8 0.2 0.0031 17.2 0.1 1.8 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger ADIP PF11559.8 CEH15963.1 - 2e-14 54.0 10.3 2e-14 54.0 10.3 3.9 4 1 1 5 5 5 1 Afadin- and alpha -actinin-Binding TetR_C_34 PF17929.1 CEH15963.1 - 0.0013 18.8 0.6 0.013 15.6 0.0 2.9 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain CPSase_sm_chain PF00988.22 CEH15964.1 - 3.7e-45 152.9 0.0 6.2e-45 152.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CEH15964.1 - 4.3e-36 124.5 0.0 5.9e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CEH15964.1 - 1.9e-05 24.5 1.2 0.044 13.5 0.2 2.8 2 1 1 3 3 3 2 Peptidase C26 RT_RNaseH PF17917.1 CEH15967.1 - 3.7e-32 110.7 0.4 7.4e-32 109.8 0.4 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEH15967.1 - 3.3e-28 97.7 0.1 6.7e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEH15967.1 - 2.5e-23 82.8 0.0 4.6e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEH15967.1 - 4e-18 65.3 0.0 9.2e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CEH15967.1 - 4.4e-13 48.9 0.0 9.7e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CEH15967.1 - 5.7e-10 39.4 0.0 1.9e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 CEH15969.1 - 1.8e-23 82.4 0.0 3.3e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEH15969.1 - 9.3e-19 67.7 0.0 2.2e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEH15969.1 - 2.3e-15 56.8 0.0 6.2e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEH15969.1 - 2.3e-11 43.6 0.0 5.3e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CEH15969.1 - 2.7e-09 36.9 0.0 4.6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CEH15969.1 - 0.0017 19.0 0.1 0.0041 17.7 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 CEH15969.1 - 0.032 14.5 0.0 0.089 13.0 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Inhibitor_I42 PF09394.10 CEH15970.1 - 0.1 13.0 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 FAM184 PF15665.5 CEH15972.1 - 0.041 13.7 0.1 0.045 13.5 0.1 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B PTPLA PF04387.14 CEH15975.1 - 1.2e-51 174.8 3.8 1.9e-51 174.1 3.8 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Glycos_transf_2 PF00535.26 CEH15976.1 - 2.5e-21 76.2 0.0 4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CEH15976.1 - 6.1e-07 29.6 0.0 1.5e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CEH15976.1 - 0.0053 17.3 0.0 0.016 15.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CEH15976.1 - 0.043 13.3 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Presenilin PF01080.17 CEH15977.1 - 9.7 4.8 7.0 15 4.3 7.0 1.2 1 0 0 1 1 1 0 Presenilin BAR PF03114.18 CEH15978.1 - 3.2e-48 164.4 2.7 3.8e-48 164.2 2.7 1.1 1 0 0 1 1 1 1 BAR domain AAA_13 PF13166.6 CEH15978.1 - 0.016 13.9 0.8 0.021 13.5 0.8 1.3 1 0 0 1 1 1 0 AAA domain HAUS-augmin3 PF14932.6 CEH15978.1 - 0.023 14.3 0.9 0.033 13.8 0.2 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Arfaptin PF06456.13 CEH15978.1 - 0.055 13.0 2.1 0.085 12.4 2.1 1.3 1 1 0 1 1 1 0 Arfaptin-like domain Cpn60_TCP1 PF00118.24 CEH15981.1 - 1e-146 489.5 11.2 1.1e-146 489.3 11.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_pol3_beta PF00712.19 CEH15981.1 - 0.0077 16.4 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III beta subunit, N-terminal domain CRM1_repeat PF18777.1 CEH15981.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Glycogen_syn PF05693.13 CEH15981.1 - 0.16 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase BCDHK_Adom3 PF10436.9 CEH15983.1 - 1.5e-61 207.0 0.0 3.2e-61 205.9 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CEH15983.1 - 1.3e-12 48.2 0.0 2.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEH15983.1 - 0.00024 20.9 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA PF00004.29 CEH15984.1 - 5.5e-45 153.0 0.0 3.2e-44 150.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CEH15984.1 - 2.9e-09 36.7 0.1 1.8e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CEH15984.1 - 1.9e-08 34.4 0.1 6.3e-08 32.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEH15984.1 - 7.2e-08 33.0 0.5 3.1e-05 24.4 0.0 3.0 2 2 2 4 4 4 1 AAA ATPase domain AAA_2 PF07724.14 CEH15984.1 - 8.4e-08 32.5 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CEH15984.1 - 3.8e-06 26.3 0.1 1.9e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CEH15984.1 - 3.9e-05 24.0 0.7 0.01 16.1 0.1 2.9 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CEH15984.1 - 0.00028 20.7 0.0 0.00076 19.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 CEH15984.1 - 0.00034 20.4 0.1 0.00094 18.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CEH15984.1 - 0.00045 20.5 0.4 0.0018 18.5 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 CEH15984.1 - 0.00056 20.5 0.0 0.0027 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CEH15984.1 - 0.00067 19.6 0.3 0.0038 17.2 0.0 2.3 3 0 0 3 3 3 1 NTPase TIP49 PF06068.13 CEH15984.1 - 0.0014 18.0 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 CEH15984.1 - 0.0017 18.4 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CEH15984.1 - 0.002 18.1 0.0 0.0049 16.9 0.0 1.6 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CEH15984.1 - 0.0026 17.3 0.1 0.017 14.7 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CEH15984.1 - 0.0037 17.6 0.0 0.0078 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_lid_3 PF17862.1 CEH15984.1 - 0.0042 16.8 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 CEH15984.1 - 0.0044 17.2 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CEH15984.1 - 0.0045 16.4 0.2 0.64 9.4 0.0 2.9 3 0 0 3 3 3 1 Bacterial TniB protein Mg_chelatase PF01078.21 CEH15984.1 - 0.0075 15.7 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CEH15984.1 - 0.0081 16.1 0.1 0.071 13.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_3 PF07726.11 CEH15984.1 - 0.0083 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CEH15984.1 - 0.0095 15.7 0.2 0.032 14.0 0.0 2.1 3 0 0 3 3 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 CEH15984.1 - 0.026 14.3 0.2 0.049 13.4 0.2 1.5 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CEH15984.1 - 0.044 13.7 0.5 0.39 10.6 0.0 2.5 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 CEH15984.1 - 0.049 13.4 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 CEH15984.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 1 0 Bacterial dnaA protein AAA_23 PF13476.6 CEH15984.1 - 0.062 13.8 0.7 0.62 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CEH15984.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.16 CEH15984.1 - 0.074 11.9 0.1 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase AAA_29 PF13555.6 CEH15984.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CEH15984.1 - 0.12 12.0 1.7 0.2 11.2 0.5 2.0 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CEH15984.1 - 0.12 12.7 0.1 0.4 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CEH15984.1 - 0.12 12.1 0.2 1.4 8.6 0.0 2.5 3 1 0 3 3 2 0 Sigma-54 interaction domain ATPase PF06745.13 CEH15984.1 - 0.13 11.6 0.0 0.62 9.4 0.0 2.0 2 0 0 2 2 2 0 KaiC Ctr PF04145.15 CEH15985.1 - 2.3e-26 93.2 0.6 2.7e-26 92.9 0.6 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 CEH15986.1 - 4.7e-23 81.7 12.4 1.5e-22 80.0 12.4 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEH15986.1 - 2.2e-12 47.4 0.0 3.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEH15986.1 - 2.8e-07 30.6 0.0 5.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CEH15986.1 - 2.3e-05 25.0 0.0 0.00019 22.1 0.0 2.4 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain Cpn60_TCP1 PF00118.24 CEH15988.1 - 2.3e-156 521.3 3.7 2.6e-156 521.1 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Acyl-thio_N PF12590.8 CEH15988.1 - 0.12 13.0 0.0 0.33 11.5 0.0 1.7 2 0 0 2 2 2 0 Acyl-ATP thioesterase START PF01852.19 CEH15989.1 - 5.6e-12 45.5 0.1 3.2e-08 33.2 0.1 3.1 2 1 0 2 2 2 2 START domain Med15 PF09606.10 CEH15989.1 - 0.34 9.5 11.8 0.56 8.8 11.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal gag_pre-integrs PF13976.6 CEH15994.1 - 2.5e-05 24.0 0.2 5.1e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-RRN7 PF11781.8 CEH15994.1 - 0.22 11.2 3.3 0.26 11.0 0.6 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RVT_2 PF07727.14 CEH15995.1 - 6.4e-58 196.3 0.0 8.4e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Proteasome PF00227.26 CEH15995.1 - 0.0042 16.6 0.1 0.02 14.3 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit DUF4310 PF14187.6 CEH15998.1 - 0.021 14.5 0.8 0.034 13.8 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) DUF3389 PF11869.8 CEH15998.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3389) Big_8 PF17961.1 CEH15998.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig domain ZZ PF00569.17 CEH15999.1 - 2e-09 37.1 32.5 8.2e-07 28.7 11.0 3.1 3 0 0 3 3 3 2 Zinc finger, ZZ type Peptidase_M20 PF01546.28 CEH15999.1 - 0.13 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 C1_2 PF03107.16 CEH15999.1 - 4.4 7.7 33.8 4.1 7.8 12.4 3.4 3 0 0 3 3 3 0 C1 domain Gly-zipper_Omp PF13488.6 CEH16000.1 - 0.0048 16.9 4.0 0.012 15.6 4.0 1.6 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_OmpA PF13436.6 CEH16000.1 - 0.035 13.9 2.8 0.083 12.7 2.8 1.6 1 0 0 1 1 1 0 Glycine-zipper domain DUF347 PF03988.12 CEH16000.1 - 0.036 14.3 0.1 0.1 12.8 0.1 1.8 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Gly-zipper_YMGG PF13441.6 CEH16000.1 - 0.055 13.2 3.6 0.13 12.0 3.6 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 CEH16000.1 - 0.08 12.8 4.9 0.22 11.4 4.9 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain LapA_dom PF06305.11 CEH16000.1 - 0.25 11.2 4.8 0.39 10.6 0.4 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain HSP70 PF00012.20 CEH16002.1 - 0.007 14.6 0.0 0.031 12.5 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein Thymopoietin PF08198.11 CEH16002.1 - 0.14 11.8 0.0 0.46 10.1 0.0 1.9 1 0 0 1 1 1 0 Thymopoietin protein OTU PF02338.19 CEH16004.1 - 0.00096 19.6 0.4 0.0029 18.1 0.1 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease DUF4246 PF14033.6 CEH16006.1 - 1.2e-114 383.9 0.0 2.1e-114 383.2 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4246) HLH PF00010.26 CEH16007.1 - 1.2e-05 25.1 0.0 3.5e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain LETM1 PF07766.13 CEH16008.1 - 1.4e-101 339.4 2.6 1.4e-101 339.4 2.6 2.5 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 CEH16008.1 - 4.6e-05 23.8 6.0 0.00025 21.4 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CEH16008.1 - 0.00069 19.4 0.1 2.4 8.3 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CEH16008.1 - 0.011 15.2 2.4 0.4 10.3 0.0 3.8 4 0 0 4 4 4 0 EF hand DUF3719 PF12516.8 CEH16008.1 - 0.016 14.9 0.1 0.048 13.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) EF-hand_8 PF13833.6 CEH16008.1 - 0.018 14.9 1.2 0.071 13.0 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain pair DUF3677 PF12432.8 CEH16008.1 - 0.15 12.4 1.3 1 9.7 1.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) EXOSC1 PF10447.9 CEH16008.1 - 2.1 9.0 5.3 1.1 9.9 1.0 2.5 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Mob_synth_C PF06463.13 CEH16009.1 - 2.8e-34 117.8 0.0 2.6e-33 114.7 0.0 2.1 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C MoaC PF01967.21 CEH16010.1 - 3.7e-14 53.0 1.7 2.6e-12 47.0 1.7 2.1 1 1 0 1 1 1 1 MoaC family zf-C2H2 PF00096.26 CEH16011.1 - 0.062 13.8 4.0 0.13 12.7 4.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Sfi1_C PF10638.9 CEH16011.1 - 0.13 13.1 0.0 0.83 10.4 0.0 2.1 2 0 0 2 2 2 0 Spindle body associated protein C-terminus Pilosulin PF17499.2 CEH16012.1 - 0.079 13.1 0.2 0.86 9.8 0.0 2.1 2 0 0 2 2 2 0 Ant venom peptides Cpn60_TCP1 PF00118.24 CEH16014.1 - 7.3e-148 493.2 4.1 9.4e-119 397.2 0.8 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family DEAD PF00270.29 CEH16015.1 - 7.4e-50 169.1 0.0 3e-49 167.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH16015.1 - 3.8e-25 88.4 0.0 1.4e-24 86.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH16015.1 - 0.019 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NuDC PF16273.5 CEH16015.1 - 0.25 11.9 0.1 0.25 11.9 0.1 4.6 4 0 0 4 4 4 0 Nuclear distribution C domain PLDc_2 PF13091.6 CEH16016.1 - 2e-05 24.5 0.0 4.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 CEH16016.1 - 0.0017 18.5 1.5 0.039 14.1 0.0 2.4 2 0 0 2 2 2 1 Phospholipase D Active site motif PNP_UDP_1 PF01048.20 CEH16018.1 - 3.2e-22 78.9 0.3 4.1e-22 78.6 0.3 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily ThiF PF00899.21 CEH16020.1 - 5.6e-35 120.9 0.0 1.4e-34 119.6 0.0 1.5 1 1 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CEH16020.1 - 0.02 15.2 0.4 0.071 13.4 0.3 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CEH16020.1 - 0.23 11.7 0.1 0.4 10.9 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain TRAPPC9-Trs120 PF08626.11 CEH16021.1 - 6.9e-21 73.4 0.0 8.6e-21 73.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Mo-co_dimer PF03404.16 CEH16021.1 - 0.033 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Herpes_ori_bp PF02399.15 CEH16021.1 - 0.16 10.0 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein TRAPPC9-Trs120 PF08626.11 CEH16022.1 - 2.9e-72 243.6 0.0 3.4e-70 236.8 0.0 2.0 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit KAsynt_C_assoc PF16197.5 CEH16022.1 - 0.0083 16.6 0.1 0.036 14.5 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension HEAT_2 PF13646.6 CEH16023.1 - 0.0068 16.8 0.6 5.2 7.5 0.1 3.1 1 1 1 2 2 2 2 HEAT repeats XhlA PF10779.9 CEH16025.1 - 3.8 7.8 5.1 3.6 7.8 0.2 3.2 2 1 1 3 3 3 0 Haemolysin XhlA NTF2 PF02136.20 CEH16026.1 - 3.8e-35 121.0 0.2 4.2e-35 120.9 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 CEH16026.1 - 7.4e-05 23.1 0.0 8.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 CEH16026.1 - 0.017 15.7 0.0 0.022 15.4 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain TpcC PF12642.7 CEH16026.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Conjugative transposon protein TcpC SRP-alpha_N PF04086.13 CEH16027.1 - 6.4e-46 157.6 0.4 9.4e-46 157.0 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 CEH16027.1 - 1e-41 142.7 0.7 4.5e-31 108.0 0.2 3.2 1 1 1 2 2 2 2 SRP54-type protein, GTPase domain SRP54_N PF02881.19 CEH16027.1 - 2.5e-08 34.0 0.0 7.1e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 CEH16027.1 - 0.0011 19.4 0.7 0.049 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 CEH16027.1 - 0.0059 16.7 0.0 0.018 15.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 CEH16027.1 - 0.016 15.5 0.0 0.072 13.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CEH16027.1 - 0.055 13.2 0.0 0.2 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 CEH16027.1 - 0.062 12.5 0.0 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase DUF3533 PF12051.8 CEH16028.1 - 4.5e-80 269.4 17.3 5.3e-80 269.2 17.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.7 CEH16028.1 - 4.2e-06 26.1 24.2 5.9e-06 25.6 24.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein NIF PF03031.18 CEH16029.1 - 1.1e-41 142.3 0.0 1.9e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PRELI PF04707.14 CEH16030.1 - 2.6e-31 108.6 0.0 3.6e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Aminotran_4 PF01063.19 CEH16030.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Amino-transferase class IV Ribosomal_L22 PF00237.19 CEH16031.1 - 4.8e-37 126.3 0.0 6.4e-37 125.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Proteasome PF00227.26 CEH16033.1 - 1.4e-36 125.8 0.0 1.6e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 CEH16033.1 - 0.00021 21.3 0.0 0.031 14.4 0.0 2.2 2 0 0 2 2 2 2 Phage late-transcription coactivator Ribosomal_L5_C PF00673.21 CEH16034.1 - 7.1e-13 48.5 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CEH16034.1 - 0.018 15.4 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L5 DUF1908 PF08926.11 CEH16034.1 - 0.29 10.2 3.2 0.51 9.4 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1908) PGI PF00342.19 CEH16035.1 - 2e-223 742.4 0.0 2.3e-223 742.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase C2 PF00168.30 CEH16036.1 - 1e-22 80.4 0.0 1.7e-14 53.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain TMEM208_SND2 PF05620.11 CEH16037.1 - 1.4e-42 145.4 1.8 2.7e-42 144.4 1.8 1.4 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF5367 PF17329.2 CEH16037.1 - 2.2 8.4 7.5 1.5 9.0 4.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5367) Med18 PF09637.10 CEH16038.1 - 0.033 14.0 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Med18 protein Forkhead PF00250.18 CEH16039.1 - 1.7e-22 79.5 0.0 3.6e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain THF_DHG_CYH PF00763.23 CEH16039.1 - 1.5e-21 76.9 0.0 2.4e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CEH16039.1 - 2.4e-11 43.2 0.0 1e-07 31.4 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TPR_1 PF00515.28 CEH16040.1 - 7.6e-15 54.0 8.3 0.00057 19.6 0.9 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEH16040.1 - 3.1e-14 52.4 8.6 9.6e-05 22.0 0.4 4.2 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.17 CEH16040.1 - 2.4e-13 49.1 11.5 4.8e-05 23.1 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEH16040.1 - 7.6e-12 45.7 3.8 2.2e-10 41.0 0.7 2.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEH16040.1 - 1.5e-09 38.0 6.7 0.0018 18.6 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEH16040.1 - 4.4e-09 36.7 8.0 0.0004 20.8 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEH16040.1 - 2.8e-08 33.9 9.6 0.057 14.3 0.3 4.3 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEH16040.1 - 6.9e-07 29.2 3.5 0.18 12.2 0.2 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 CEH16040.1 - 1.8e-06 28.2 2.6 0.0095 16.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEH16040.1 - 3.5e-06 27.1 1.8 0.00014 22.0 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEH16040.1 - 4.4e-06 26.5 6.6 0.05 13.8 0.1 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH16040.1 - 0.0022 18.2 3.6 0.0048 17.1 0.6 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 YfiO PF13525.6 CEH16040.1 - 0.015 15.0 0.2 0.028 14.2 0.2 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein NYD-SP12_N PF15015.6 CEH16040.1 - 0.015 13.7 0.1 0.017 13.5 0.1 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal TPR_7 PF13176.6 CEH16040.1 - 0.082 13.0 3.7 2.6 8.3 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEH16040.1 - 0.13 12.2 5.0 7.3 6.6 0.8 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SPC25 PF06703.11 CEH16041.1 - 4.2e-35 120.9 0.0 4.9e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Lactamase_B_3 PF13483.6 CEH16042.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain TRAP_alpha PF03896.16 CEH16043.1 - 3.5e-05 23.2 0.0 5.6e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit UvdE PF03851.14 CEH16044.1 - 2.5e-81 273.0 0.0 3.5e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE His_Phos_2 PF00328.22 CEH16045.1 - 4.6e-06 26.2 0.3 0.015 14.7 0.0 2.8 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) Sulfate_transp PF00916.20 CEH16046.1 - 1.4e-111 372.9 20.0 1.8e-111 372.6 20.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CEH16046.1 - 5.9e-07 29.1 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.10 CEH16046.1 - 0.13 12.2 2.2 0.96 9.5 2.2 2.5 1 0 0 1 1 1 0 Stannin transmembrane MFS_MOT1 PF16983.5 CEH16046.1 - 0.29 11.5 14.8 0.66 10.4 2.6 3.3 3 2 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF2034 PF10356.9 CEH16047.1 - 3.2e-14 52.8 0.0 8.3e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 CEH16047.1 - 0.13 12.3 0.1 1 9.4 0.0 2.4 2 1 0 2 2 2 0 Restriction endonuclease MFS_1 PF07690.16 CEH16049.1 - 1.7e-37 129.2 40.8 1.7e-37 129.2 40.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH16049.1 - 2.7e-15 56.2 16.8 2.7e-15 56.2 5.1 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 CEH16049.1 - 9e-13 47.5 17.0 1.3e-12 47.0 17.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fst_toxin PF13955.6 CEH16049.1 - 0.8 9.7 6.0 11 6.1 0.5 3.3 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system DUF5325 PF17259.2 CEH16049.1 - 2.8 7.9 5.7 0.56 10.1 0.2 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Hydrolase_4 PF12146.8 CEH16050.1 - 1.8e-27 96.1 1.0 3.5e-27 95.2 1.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEH16050.1 - 1.3e-07 32.4 0.2 2.7e-07 31.4 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEH16050.1 - 1e-06 28.6 0.2 0.00024 20.8 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 CEH16050.1 - 6.6e-05 22.6 0.1 0.37 10.3 0.0 3.1 3 0 0 3 3 3 2 Dienelactone hydrolase family Esterase PF00756.20 CEH16050.1 - 0.05 13.2 0.1 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Putative esterase RasGEF PF00617.19 CEH16051.1 - 4.8e-58 196.3 0.2 8.1e-58 195.5 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CEH16051.1 - 2.1e-29 101.9 0.2 4.7e-29 100.7 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 CEH16051.1 - 1.8e-11 43.4 0.1 3.9e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEH16051.1 - 1.8e-09 37.1 0.0 4.4e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CEH16051.1 - 1.2e-08 34.7 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 CEH16051.1 - 0.00049 20.1 0.0 0.023 14.8 0.0 2.5 2 0 0 2 2 2 1 WW domain Polyoma_agno PF01736.16 CEH16051.1 - 0.16 11.7 0.1 0.4 10.4 0.1 1.7 1 0 0 1 1 1 0 Polyomavirus agnoprotein Isy1 PF06246.12 CEH16053.1 - 3.7e-85 285.6 0.4 5.1e-85 285.1 0.4 1.2 1 0 0 1 1 1 1 Isy1-like splicing family Bot1p PF12298.8 CEH16054.1 - 2.9e-23 82.9 0.8 3.3e-22 79.5 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein zf-RING_2 PF13639.6 CEH16057.1 - 3.9e-09 36.7 16.5 2.5e-07 30.9 5.1 3.6 3 1 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 CEH16057.1 - 2.7e-08 33.7 3.1 2e-05 24.5 0.0 3.3 2 1 1 3 3 3 2 RING-type zinc-finger zf-rbx1 PF12678.7 CEH16057.1 - 4.2e-05 23.7 14.4 0.0013 19.0 5.2 3.2 3 0 0 3 3 3 2 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CEH16057.1 - 0.0021 17.9 10.7 0.0086 15.9 2.8 3.5 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CEH16057.1 - 0.0027 17.4 12.8 0.09 12.5 0.2 3.8 4 0 0 4 4 4 2 RING-like zinc finger zf-RING_5 PF14634.6 CEH16057.1 - 0.0036 17.2 11.7 0.016 15.2 2.2 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CEH16057.1 - 0.0042 16.9 13.5 0.018 14.9 2.8 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEH16057.1 - 0.0073 16.3 0.9 0.0073 16.3 0.9 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CEH16057.1 - 0.014 15.5 3.4 0.014 15.5 3.4 2.1 2 1 0 2 2 2 0 RING-variant domain Zn_ribbon_17 PF17120.5 CEH16057.1 - 0.26 10.9 11.4 0.48 10.1 3.6 3.4 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CEH16057.1 - 0.7 9.8 12.3 0.1 12.5 3.0 3.3 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEH16057.1 - 0.76 9.7 20.4 0.077 12.9 0.7 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CEH16057.1 - 1.7 8.6 18.0 0.39 10.6 2.4 4.3 5 0 0 5 5 5 0 PHD-finger ThiF PF00899.21 CEH16058.1 - 2.9e-65 220.0 0.0 4.3e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 CEH16058.1 - 7.8e-15 55.5 0.1 6e-10 39.5 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 CEH16058.1 - 2.8e-07 31.0 0.1 3.3e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 CEH16058.1 - 0.015 15.7 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 CEH16058.1 - 0.015 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Dermcidin PF15291.6 CEH16058.1 - 0.16 12.5 0.1 0.16 12.5 0.1 2.1 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide DUF2407_C PF13373.6 CEH16058.1 - 0.29 11.3 0.8 0.61 10.3 0.8 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain Abhydrolase_1 PF00561.20 CEH16059.1 - 1.4e-44 152.7 0.1 4.6e-42 144.4 0.1 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 CEH16059.1 - 4.8e-05 23.1 0.2 8e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CEH16059.1 - 7.5e-05 22.1 0.1 0.038 13.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEH16059.1 - 0.015 15.9 6.6 0.05 14.2 6.6 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.28 CEH16062.1 - 1.7e-77 261.5 0.0 3.1e-77 260.6 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CEH16062.1 - 2.8e-09 37.2 2.9 0.0003 20.7 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold MG2 PF01835.19 CEH16063.1 - 0.049 14.1 0.0 0.086 13.3 0.0 1.6 1 0 0 1 1 1 0 MG2 domain F-box-like PF12937.7 CEH16064.1 - 0.00022 21.0 0.4 0.00044 20.1 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEH16064.1 - 0.001 18.9 0.6 0.002 18.0 0.6 1.4 1 0 0 1 1 1 1 F-box domain Mito_fiss_reg PF05308.11 CEH16064.1 - 4.9 7.2 8.5 0.34 10.9 2.8 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator ECH_1 PF00378.20 CEH16065.1 - 1.1e-35 123.1 0.0 2.9e-35 121.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEH16065.1 - 2.8e-14 53.3 0.0 1.7e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase GATase_6 PF13522.6 CEH16066.1 - 5.1e-13 49.4 0.0 1.5e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CEH16066.1 - 2.3e-09 37.2 0.0 4.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 CEH16066.1 - 1.1e-08 34.7 0.1 1.9e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 CEH16066.1 - 1.2e-05 24.3 0.0 2.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glyco_transf_90 PF05686.12 CEH16068.1 - 5e-22 78.4 7.2 6.6e-18 64.8 4.6 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 Methyltransf_23 PF13489.6 CEH16068.1 - 0.075 12.9 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain SKG6 PF08693.10 CEH16070.1 - 0.48 9.9 3.0 0.81 9.1 3.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PTR2 PF00854.21 CEH16071.1 - 2.4e-82 276.9 4.9 3.1e-82 276.5 4.9 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 CEH16071.1 - 1.5e-12 47.1 14.8 5.5e-12 45.3 11.7 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily SAE2 PF08573.10 CEH16072.1 - 6.4e-08 33.7 4.3 3.9e-05 24.7 0.3 5.7 4 2 1 5 5 5 2 DNA repair protein endonuclease SAE2/CtIP C-terminus HALZ PF02183.18 CEH16072.1 - 0.037 14.2 0.3 0.037 14.2 0.3 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper GIT_CC PF16559.5 CEH16072.1 - 0.55 10.1 4.3 0.18 11.7 0.6 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor UBX PF00789.20 CEH16074.1 - 1.1e-09 38.4 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain Rubrerythrin PF02915.17 CEH16075.1 - 0.14 12.6 2.2 0.93 9.9 1.6 2.0 1 1 1 2 2 2 0 Rubrerythrin Glyco_hydro_18 PF00704.28 CEH16076.1 - 2.3e-73 247.7 0.0 2.6e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HIG_1_N PF04588.13 CEH16077.1 - 2.9e-16 59.4 0.2 4.1e-16 58.9 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Zn_clus PF00172.18 CEH16078.1 - 6.8e-07 29.3 7.6 1.5e-06 28.2 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CEH16078.1 - 0.0028 16.7 0.0 0.012 14.7 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Med26 PF08711.11 CEH16078.1 - 0.035 14.1 0.1 0.083 12.9 0.1 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Peptidase_S9 PF00326.21 CEH16079.1 - 1.5e-08 34.3 1.2 6.8e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CEH16079.1 - 1.4e-06 28.3 0.1 0.0036 17.2 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold LIP PF03583.14 CEH16079.1 - 0.027 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_2 PF02230.16 CEH16079.1 - 0.038 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 CEH16079.1 - 0.067 13.1 0.0 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 CEH16079.1 - 0.068 12.4 0.1 1.6 8.0 0.0 2.4 2 1 0 3 3 3 0 Serine aminopeptidase, S33 ASL_C2 PF14698.6 CEH16081.1 - 2.2e-24 86.0 0.0 4.3e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Lyase_1 PF00206.20 CEH16081.1 - 1.4e-10 41.1 0.0 2.9e-10 40.1 0.0 1.5 2 0 0 2 2 2 1 Lyase Lyase_1 PF00206.20 CEH16082.1 - 3e-80 269.9 0.0 3.4e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Lyase SHE3 PF17078.5 CEH16083.1 - 0.00027 20.8 19.8 0.0021 17.8 4.4 2.8 2 1 1 3 3 3 2 SWI5-dependent HO expression protein 3 WD40_alt PF14077.6 CEH16083.1 - 0.056 13.3 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF1664 PF07889.12 CEH16083.1 - 1 9.4 12.1 0.59 10.2 0.6 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Sterol-sensing PF12349.8 CEH16084.1 - 9.7e-44 148.9 14.9 1.7e-43 148.1 14.9 1.3 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CEH16084.1 - 1.1e-14 53.5 7.1 1.6e-14 53.0 7.1 1.1 1 0 0 1 1 1 1 Patched family ANAPC4_WD40 PF12894.7 CEH16084.1 - 0.0035 17.6 0.0 0.029 14.7 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEH16084.1 - 1.9 9.5 4.5 15 6.6 0.7 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat Cation_efflux PF01545.21 CEH16085.1 - 1.9e-30 106.1 18.1 2e-30 106.0 13.3 2.6 2 1 0 2 2 2 2 Cation efflux family CLPTM1 PF05602.12 CEH16086.1 - 7.6e-89 298.7 0.0 2.2e-87 293.9 0.0 2.3 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 CEH16086.1 - 0.00078 19.2 1.4 0.00078 19.2 1.4 1.8 2 0 0 2 2 2 1 PQ loop repeat GPI-anchored PF10342.9 CEH16088.1 - 2.8e-05 24.8 0.0 4.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family V-SNARE_C PF12352.8 CEH16089.1 - 1.2e-17 63.9 5.6 2.7e-17 62.8 5.6 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CEH16089.1 - 0.048 13.6 0.7 0.2 11.6 0.0 2.3 3 0 0 3 3 3 0 Sec20 DUF1644 PF07800.12 CEH16089.1 - 0.1 12.6 0.5 0.22 11.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) DNA_pol_A_exo1 PF01612.20 CEH16090.1 - 8.9e-35 120.0 0.1 1.6e-34 119.2 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CEH16090.1 - 1.8e-12 47.8 0.0 5.2e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 CEH16090.1 - 3.6e-09 36.5 0.1 1e-08 35.0 0.1 1.8 1 0 0 1 1 1 1 HRDC domain BLOC1_2 PF10046.9 CEH16092.1 - 0.0009 19.5 0.1 0.0017 18.6 0.1 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 HEM4 PF02602.15 CEH16092.1 - 0.0067 15.8 0.0 0.0075 15.6 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF4456 PF14644.6 CEH16092.1 - 0.079 12.6 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) CCCAP PF15964.5 CEH16092.1 - 0.16 10.2 0.0 0.16 10.2 0.0 1.0 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family DUF3818 PF12825.7 CEH16094.1 - 8.8e-43 146.6 0.0 1.2e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) Epimerase PF01370.21 CEH16095.1 - 1.1e-17 64.3 0.0 2e-17 63.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CEH16095.1 - 9.1e-12 44.7 0.0 1.7e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 CEH16095.1 - 6.2e-11 41.8 0.0 8.7e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CEH16095.1 - 4.9e-10 39.6 0.3 2.3e-09 37.4 0.1 2.2 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 CEH16095.1 - 5.5e-10 39.2 0.1 7.2e-09 35.5 0.4 2.2 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 CEH16095.1 - 2.8e-09 36.8 0.1 4.6e-09 36.1 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CEH16095.1 - 8e-07 28.5 0.0 1.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 CEH16095.1 - 0.03 13.8 0.0 0.065 12.7 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Clat_adaptor_s PF01217.20 CEH16096.1 - 3.9e-17 62.5 0.1 4.8e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA PF00004.29 CEH16097.1 - 3e-12 47.1 0.0 7.3e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CEH16097.1 - 1.4e-06 28.4 0.1 0.00055 19.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 CEH16097.1 - 9.3e-06 25.5 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CEH16097.1 - 0.00018 21.5 0.0 0.0019 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEH16097.1 - 0.0021 18.4 5.5 0.0024 18.3 0.0 3.5 4 1 1 5 5 3 1 AAA ATPase domain AAA_5 PF07728.14 CEH16097.1 - 0.0026 17.8 0.0 0.0058 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 CEH16097.1 - 0.0082 16.5 0.1 0.034 14.5 0.1 2.1 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 CEH16097.1 - 0.0099 16.2 0.0 0.27 11.5 0.0 2.5 1 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 CEH16097.1 - 0.014 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 CEH16097.1 - 0.033 14.3 0.0 0.13 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CEH16097.1 - 0.041 13.5 0.0 0.56 9.8 0.0 2.4 1 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CEH16097.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 CEH16097.1 - 0.049 14.2 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CEH16097.1 - 0.083 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 CEH16097.1 - 0.089 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CEH16097.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CEH16097.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 CEH16097.1 - 0.79 9.9 0.0 0.79 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain Chitin_synth_2 PF03142.15 CEH16098.1 - 2.3e-283 940.6 0.0 3.2e-283 940.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CEH16098.1 - 1.2e-12 48.2 0.1 3.3e-12 46.8 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEH16098.1 - 4.3e-12 46.4 0.9 1.3e-11 44.8 0.9 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 CEH16098.1 - 4.1e-05 23.1 0.0 0.0062 16.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CEH16098.1 - 0.033 14.0 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Fungal_trans PF04082.18 CEH16099.1 - 1.3e-10 40.7 0.0 1.1e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CEH16099.1 - 7.2e-06 26.2 7.0 0.0016 18.8 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEH16099.1 - 0.016 16.0 0.7 0.016 16.0 0.7 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEH16099.1 - 2.2 8.9 4.9 0.51 10.9 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 CEH16099.1 - 3.1 7.9 8.2 1 9.5 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger YchF-GTPase_C PF06071.13 CEH16100.1 - 3.1e-34 117.0 0.1 8.6e-34 115.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CEH16100.1 - 1.6e-16 60.4 0.0 5.4e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH16100.1 - 3.5e-05 23.4 0.0 6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GATA PF00320.27 CEH16101.1 - 5.7e-14 51.4 3.2 1e-13 50.6 3.2 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CEH16101.1 - 0.082 12.4 0.5 0.14 11.7 0.5 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding YidD PF01809.18 CEH16102.1 - 0.081 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative membrane protein insertion efficiency factor PLU-1 PF08429.11 CEH16103.1 - 3.4e-50 171.1 0.1 6e-50 170.3 0.1 1.4 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.22 CEH16103.1 - 2e-41 141.0 0.2 4.6e-41 139.8 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 CEH16103.1 - 4.8e-26 90.4 51.8 4.7e-13 48.8 3.5 3.9 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 CEH16103.1 - 6.1e-17 62.1 0.0 3.1e-16 59.8 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 CEH16103.1 - 1.8e-14 53.4 0.1 4.7e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 CEH16103.1 - 6e-11 42.6 3.6 6e-11 42.6 3.6 2.3 3 0 0 3 3 3 1 C5HC2 zinc finger Prok-RING_1 PF14446.6 CEH16103.1 - 0.84 9.6 24.3 0.097 12.6 2.9 3.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 CEH16103.1 - 5 7.3 22.8 0.14 12.3 0.5 3.9 3 0 0 3 3 3 0 KIAA1045 RING finger Vps54 PF07928.12 CEH16104.1 - 1.2e-53 181.1 1.6 2.2e-53 180.3 1.6 1.5 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.9 CEH16104.1 - 0.00037 20.4 0.1 0.00063 19.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 CEH16104.1 - 0.014 14.4 1.0 0.017 14.0 0.1 1.5 2 0 0 2 2 2 0 RINT-1 / TIP-1 family Urb2 PF10441.9 CEH16104.1 - 0.84 9.5 4.2 1.4 8.8 2.0 2.2 1 1 1 2 2 2 0 Urb2/Npa2 family zf-MYND PF01753.18 CEH16105.1 - 8.7e-08 32.1 13.9 1.8e-07 31.1 13.9 1.6 1 0 0 1 1 1 1 MYND finger TIP49 PF06068.13 CEH16106.1 - 2.3e-156 520.4 0.1 3e-156 520.0 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CEH16106.1 - 7.9e-22 77.2 1.2 7.9e-22 77.2 1.2 2.4 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 CEH16106.1 - 6.5e-10 39.5 1.8 1.5e-07 31.9 0.1 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEH16106.1 - 8.4e-08 32.1 0.3 0.00031 20.5 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEH16106.1 - 1.6e-05 25.2 0.2 0.21 11.8 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 CEH16106.1 - 2.4e-05 24.3 0.1 0.01 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 CEH16106.1 - 3.3e-05 23.3 0.1 6.5e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 CEH16106.1 - 3.5e-05 23.5 1.1 0.00013 21.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEH16106.1 - 4.7e-05 23.8 0.5 4.7e-05 23.8 0.5 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 CEH16106.1 - 0.00018 21.9 2.4 0.0013 19.1 0.8 2.7 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CEH16106.1 - 0.0003 20.3 0.4 0.012 15.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 CEH16106.1 - 0.00076 19.9 0.3 0.0019 18.6 0.3 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CEH16106.1 - 0.0027 17.4 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 CEH16106.1 - 0.0031 17.0 0.1 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 CEH16106.1 - 0.0082 15.9 1.3 0.097 12.4 0.8 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CEH16106.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Prot_ATP_ID_OB PF16450.5 CEH16106.1 - 0.013 15.5 0.8 0.049 13.6 0.8 2.0 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain DUF2075 PF09848.9 CEH16106.1 - 0.016 14.5 0.1 0.051 12.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 CEH16106.1 - 0.016 15.4 0.0 0.044 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEH16106.1 - 0.017 15.1 0.0 0.086 12.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 CEH16106.1 - 0.019 15.5 2.4 0.026 15.1 0.0 2.4 2 1 1 3 3 2 0 AAA domain AAA_28 PF13521.6 CEH16106.1 - 0.023 14.9 1.0 0.075 13.3 0.0 2.4 2 2 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CEH16106.1 - 0.034 14.1 1.6 0.47 10.4 0.4 3.1 2 1 0 2 2 2 0 NTPase YjeF_N PF03853.15 CEH16106.1 - 0.043 13.7 0.2 0.077 12.9 0.2 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus AAA_11 PF13086.6 CEH16106.1 - 0.068 12.9 0.2 0.14 11.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CEH16106.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Pil1 PF13805.6 CEH16107.1 - 1.2e-48 165.9 0.0 2.1e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3808 PF10300.9 CEH16108.1 - 1.8e-72 244.6 0.4 3.2e-72 243.8 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.20 CEH16108.1 - 1.4e-30 106.1 0.0 3.1e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CEH16108.1 - 2.6e-12 47.1 0.1 1.3e-11 44.8 0.0 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEH16108.1 - 5e-11 42.6 5.4 9e-10 38.6 0.5 2.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain TPR_8 PF13181.6 CEH16108.1 - 0.00037 20.5 2.8 0.89 9.9 0.4 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEH16108.1 - 0.00052 20.3 2.2 8.1 6.8 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Gly-zipper_Omp PF13488.6 CEH16108.1 - 0.0013 18.7 10.7 0.42 10.6 5.4 2.4 2 0 0 2 2 2 2 Glycine zipper TPR_2 PF07719.17 CEH16108.1 - 0.0071 16.4 11.5 2.7 8.3 0.4 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEH16108.1 - 0.086 13.5 3.9 10 7.0 0.3 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEH16108.1 - 0.35 10.8 7.7 1.8 8.5 0.7 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L12 PF00542.19 CEH16109.1 - 1.3e-18 67.1 8.6 2.1e-18 66.4 6.5 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CEH16109.1 - 8.7e-14 51.0 6.8 8.7e-14 51.0 6.8 2.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain RhoGAP PF00620.27 CEH16110.1 - 0.029 14.2 0.0 0.14 12.0 0.0 2.1 2 1 0 2 2 2 0 RhoGAP domain ZapB PF06005.12 CEH16110.1 - 0.11 12.9 0.0 0.34 11.4 0.0 1.9 1 0 0 1 1 1 0 Cell division protein ZapB DUF4298 PF14131.6 CEH16110.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Polysacc_deac_1 PF01522.21 CEH16111.1 - 1e-21 77.1 0.0 3.2e-21 75.5 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Pyr_redox_2 PF07992.14 CEH16114.1 - 2.4e-25 89.4 0.0 3e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEH16114.1 - 1.4e-09 38.4 0.0 3.3e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEH16114.1 - 5.9e-06 25.8 0.0 8.6e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEH16114.1 - 0.001 18.3 0.0 0.0025 17.0 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 CEH16114.1 - 0.0073 15.4 0.6 0.025 13.6 0.1 2.1 2 1 1 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 CEH16114.1 - 0.15 11.6 2.5 12 5.4 0.0 3.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase RQC PF09382.10 CEH16115.1 - 1.7e-22 79.3 0.3 3.5e-22 78.3 0.3 1.5 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 CEH16115.1 - 1.5e-20 73.7 0.0 1.4e-19 70.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH16115.1 - 7.3e-19 68.1 0.0 3.1e-18 66.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CEH16115.1 - 3.2e-16 59.8 4.2 1.5e-15 57.7 4.2 2.3 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 CEH16115.1 - 1.1e-06 28.5 0.2 4e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 HRDC domain ResIII PF04851.15 CEH16115.1 - 9.9e-05 22.4 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PEP_hydrolase PF09370.10 CEH16115.1 - 0.084 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Pro-kuma_activ PF09286.11 CEH16116.1 - 2.6e-15 56.9 0.0 4.8e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Zn_clus PF00172.18 CEH16117.1 - 1.9e-06 27.9 10.8 3.4e-06 27.1 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CEH16117.1 - 0.0013 17.8 0.0 0.0057 15.7 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF3795 PF12675.7 CEH16117.1 - 0.19 12.1 8.4 0.42 11.1 8.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) K_oxygenase PF13434.6 CEH16118.1 - 4.5e-11 42.5 0.0 1.6e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CEH16118.1 - 0.00018 20.9 0.0 0.26 10.5 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEH16118.1 - 0.054 13.5 0.5 2.2 8.3 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CEH16118.1 - 0.059 12.4 0.1 0.099 11.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 CEH16118.1 - 0.13 12.5 0.4 17 5.7 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MIP PF00230.20 CEH16121.1 - 7.9e-46 156.6 7.3 1.2e-45 156.1 7.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF1269 PF06897.12 CEH16121.1 - 0.062 13.6 5.7 2.8 8.3 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) Peptidase_M76 PF09768.9 CEH16122.1 - 6e-63 211.7 3.3 8.1e-63 211.2 3.3 1.2 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 CEH16122.1 - 0.0016 18.3 1.5 0.0031 17.3 1.5 1.5 1 0 0 1 1 1 1 SprT-like family Proteasome PF00227.26 CEH16123.1 - 7.3e-47 159.3 0.0 9.5e-47 158.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEH16123.1 - 1.5e-13 50.1 0.8 4.7e-13 48.5 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-Mss51 PF13824.6 CEH16124.1 - 7.1e-17 61.2 0.1 1.3e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Amidohydro_1 PF01979.20 CEH16125.1 - 4.7e-66 223.5 0.6 1.1e-65 222.3 0.3 1.7 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 CEH16125.1 - 3.4e-55 185.6 1.0 6.9e-55 184.6 1.0 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 CEH16125.1 - 2.3e-41 140.1 0.8 4.8e-41 139.1 0.2 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.20 CEH16125.1 - 3.9e-34 116.6 0.0 7.5e-34 115.7 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 CEH16125.1 - 5.4e-08 32.7 0.5 7.1e-06 25.8 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family PHD PF00628.29 CEH16127.1 - 1.2e-08 34.7 11.1 2.2e-08 33.9 11.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CEH16127.1 - 0.031 13.8 7.5 0.058 13.0 7.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.6 CEH16127.1 - 0.83 9.3 4.3 0.52 9.9 1.8 2.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-CW PF07496.15 CEH16127.1 - 0.83 9.7 3.5 1.7 8.7 3.5 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger Prefoldin PF02996.17 CEH16128.1 - 2e-27 95.5 0.5 2e-27 95.5 0.5 1.3 1 1 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 CEH16128.1 - 0.058 13.6 6.2 3.2 8.0 2.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Med2 PF11214.8 CEH16128.1 - 0.17 12.0 5.2 0.23 11.6 2.1 2.0 1 1 1 2 2 2 0 Mediator complex subunit 2 OmpH PF03938.14 CEH16128.1 - 0.58 10.5 10.5 0.11 12.8 4.9 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.20 CEH16128.1 - 0.79 9.7 11.2 0.13 12.2 0.6 2.7 2 1 1 3 3 3 0 Prefoldin subunit WD40 PF00400.32 CEH16129.1 - 6.3e-38 128.1 19.0 0.00036 21.3 0.0 11.9 11 0 0 11 11 11 8 WD domain, G-beta repeat Utp12 PF04003.12 CEH16129.1 - 1.5e-16 60.6 0.7 2.6e-16 59.9 0.7 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CEH16129.1 - 2.1e-12 47.1 0.3 0.086 13.2 0.0 7.3 6 2 2 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 CEH16129.1 - 2.4e-06 27.1 0.0 0.00055 19.3 0.0 3.4 2 2 2 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 CEH16129.1 - 1.8e-05 23.9 0.1 9.1 5.1 0.0 5.2 5 1 1 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEH16129.1 - 0.0013 17.5 0.0 1.6 7.2 0.0 4.5 5 0 0 5 5 5 1 Nucleoporin Nup120/160 ECH_1 PF00378.20 CEH16130.1 - 1.3e-13 50.8 0.0 2.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEH16130.1 - 0.2 11.1 0.1 0.28 10.6 0.1 1.3 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Syja_N PF02383.18 CEH16131.1 - 3.9e-66 223.5 0.0 5.5e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CEH16131.1 - 8.1e-10 38.6 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF92 PF01940.16 CEH16133.1 - 4.8e-72 242.2 6.8 6e-72 241.9 6.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 FMO-like PF00743.19 CEH16133.1 - 0.22 9.9 0.0 0.31 9.4 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Colicin_V PF02674.16 CEH16133.1 - 9 6.3 11.4 8.9 6.3 1.3 3.0 2 2 0 2 2 2 0 Colicin V production protein EF-hand_4 PF12763.7 CEH16134.1 - 0.15 12.1 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand WD40 PF00400.32 CEH16135.1 - 1.9e-14 53.8 1.5 0.01 16.7 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH16135.1 - 2e-09 37.6 0.1 0.56 10.5 0.0 5.2 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CEH16135.1 - 0.15 12.6 1.2 1.1 9.9 0.1 2.9 4 0 0 4 4 4 0 PQQ-like domain Nucleoporin_N PF08801.11 CEH16136.1 - 3.5e-62 210.6 0.0 5.3e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CEH16136.1 - 2.4e-28 99.2 1.9 4e-28 98.5 1.9 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Cnd2 PF05786.14 CEH16137.1 - 5.5e-105 352.7 0.0 7e-105 352.4 0.0 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CEH16137.1 - 0.029 14.6 0.0 0.078 13.2 0.0 1.7 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal TauD PF02668.16 CEH16138.1 - 1.3e-53 182.5 0.3 1.8e-53 182.1 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UnbV_ASPIC PF07593.12 CEH16138.1 - 0.0015 18.4 0.6 0.71 9.9 0.1 2.7 2 0 0 2 2 2 2 ASPIC and UnbV OTU PF02338.19 CEH16140.1 - 0.0026 18.2 0.0 0.0052 17.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 CEH16140.1 - 0.028 14.9 0.0 0.073 13.6 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-C2H2_2 PF12756.7 CEH16140.1 - 0.14 12.5 0.2 0.25 11.7 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) TFIID_30kDa PF03540.13 CEH16141.1 - 2.7e-25 88.0 0.0 4.9e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.28 CEH16141.1 - 7.4e-09 35.9 0.0 0.0015 18.9 0.0 2.6 2 1 0 2 2 2 2 CBS domain TAF4 PF05236.14 CEH16141.1 - 0.07 12.9 1.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Bromo_TP PF07524.13 CEH16141.1 - 0.17 11.9 0.0 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated Ribosomal_60s PF00428.19 CEH16141.1 - 3 8.5 0.0 3 8.5 0.0 2.7 3 1 0 3 3 3 0 60s Acidic ribosomal protein Glutaredoxin PF00462.24 CEH16143.1 - 4.4e-16 58.9 0.1 6.3e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Turandot PF07240.11 CEH16143.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot DUF2752 PF10825.8 CEH16143.1 - 0.19 11.8 0.0 5.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) PLDc_2 PF13091.6 CEH16144.1 - 4.8e-18 65.3 0.0 8.4e-14 51.6 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CEH16144.1 - 0.15 12.3 0.1 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 Phospholipase D Active site motif HTH_28 PF13518.6 CEH16146.1 - 0.013 15.6 1.0 0.82 9.9 0.0 3.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 CEH16146.1 - 0.67 9.8 3.0 20 5.1 0.0 3.7 4 0 0 4 4 4 0 Homeodomain-like domain RNase_HII PF01351.18 CEH16147.1 - 6.1e-42 143.7 0.0 8.6e-39 133.4 0.0 2.3 1 1 0 1 1 1 1 Ribonuclease HII FAM70 PF14967.6 CEH16149.1 - 4.6 6.6 6.2 8.2 5.8 6.2 1.3 1 0 0 1 1 1 0 FAM70 protein WD40 PF00400.32 CEH16150.1 - 2.6e-13 50.2 7.3 1.3e-05 25.8 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH16150.1 - 0.084 13.2 0.0 6.4 7.2 0.0 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L28e PF01778.17 CEH16151.1 - 1.6e-33 115.9 1.9 4.1e-33 114.5 0.3 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CEH16151.1 - 9e-25 87.2 24.0 9e-25 87.2 24.0 2.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 CEH16151.1 - 1.2e-05 24.8 23.7 1.8e-05 24.3 23.7 1.2 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 CEH16151.1 - 0.03 14.1 1.9 0.05 13.3 1.4 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain zf_C2H2_6 PF18450.1 CEH16151.1 - 0.29 10.9 0.7 0.54 10.0 0.7 1.4 1 0 0 1 1 1 0 Zinc Finger domain Nop14 PF04147.12 CEH16151.1 - 5.1 5.2 27.5 6.7 4.8 27.5 1.2 1 0 0 1 1 1 0 Nop14-like family Nup188 PF10487.9 CEH16152.1 - 6.3e-28 97.2 0.0 3.6e-13 48.4 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 ERAP1_C PF11838.8 CEH16152.1 - 0.047 13.2 0.3 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 ERAP1-like C-terminal domain Sybindin PF04099.12 CEH16153.1 - 4.5e-34 117.4 0.0 5e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CEH16153.1 - 1.9e-06 28.0 0.0 2.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF1768 PF08719.11 CEH16154.1 - 6.8e-29 101.2 0.0 1e-28 100.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Nfu_N PF08712.11 CEH16156.1 - 6.6e-33 112.6 0.1 1.3e-32 111.6 0.1 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CEH16156.1 - 7.3e-28 96.5 0.1 1.3e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 CEH16156.1 - 0.062 13.4 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Peptidase_S9 PF00326.21 CEH16158.1 - 0.00014 21.4 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CEH16158.1 - 0.0012 18.1 0.0 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 CEH16158.1 - 0.0033 16.6 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF915 PF06028.11 CEH16158.1 - 0.0044 16.4 0.0 0.036 13.4 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 CEH16158.1 - 0.027 14.1 0.6 1.3 8.6 0.4 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold cwf21 PF08312.12 CEH16159.1 - 9.6e-14 51.3 10.3 9.6e-14 51.3 10.3 2.4 2 0 0 2 2 2 1 cwf21 domain CYSTM PF12734.7 CEH16160.1 - 0.034 14.5 41.4 0.034 14.5 41.4 4.9 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance MFS_1 PF07690.16 CEH16162.1 - 6.6e-51 173.3 45.7 8.5e-49 166.3 46.2 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CEH16162.1 - 1.6e-18 66.5 17.6 2.1e-18 66.1 17.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CEH16162.1 - 2.5e-16 59.6 3.8 2.5e-16 59.6 3.8 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter PUCC PF03209.15 CEH16162.1 - 0.003 16.6 23.0 0.038 13.0 3.7 2.4 2 0 0 2 2 2 2 PUCC protein YjcB PF15940.5 CEH16162.1 - 0.013 15.7 0.6 0.056 13.6 0.6 2.2 1 0 0 1 1 1 0 Family of unknown function ThiF PF00899.21 CEH16163.1 - 9.3e-65 218.4 0.0 1.3e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 CEH16163.1 - 2.7e-28 98.0 0.2 4.1e-28 97.4 0.2 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 CEH16163.1 - 0.0042 17.2 0.6 0.01 15.9 0.0 1.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 CEH16163.1 - 0.044 13.4 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UBA_e1_thiolCys PF10585.9 CEH16163.1 - 0.065 13.2 0.3 3.7 7.4 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site Sacchrp_dh_NADP PF03435.18 CEH16163.1 - 0.087 13.1 0.6 0.61 10.3 0.0 2.5 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 CEH16163.1 - 0.094 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 CEH16163.1 - 0.12 13.0 0.1 0.29 11.8 0.1 1.7 1 0 0 1 1 1 0 PglD N-terminal domain Retrotrans_gag PF03732.17 CEH16166.1 - 5.4e-06 26.6 1.8 1.5e-05 25.2 0.9 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein MIP PF00230.20 CEH16168.1 - 8.9e-41 140.1 12.9 1.2e-40 139.6 12.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Med21 PF11221.8 CEH16171.1 - 0.0032 17.7 0.0 0.0032 17.7 0.0 3.4 2 1 1 3 3 3 1 Subunit 21 of Mediator complex UPF0242 PF06785.11 CEH16171.1 - 0.0072 16.4 2.3 0.0089 16.1 2.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus GTP_EFTU PF00009.27 CEH16173.1 - 8.8e-41 139.6 0.0 1.3e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEH16173.1 - 3e-08 33.7 0.0 0.002 18.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 CEH16173.1 - 1.9e-07 31.4 0.0 4.2e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEH16173.1 - 0.006 16.9 0.2 0.024 15.0 0.2 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CEH16173.1 - 0.015 15.2 0.3 0.043 13.7 0.3 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 SRPRB PF09439.10 CEH16173.1 - 0.13 11.7 0.0 2.7 7.4 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CEH16173.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SLAC1 PF03595.17 CEH16175.1 - 1.1e-48 166.1 48.8 1.7e-48 165.6 48.8 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel WD40 PF00400.32 CEH16176.1 - 1.2e-11 45.0 5.1 0.0045 17.8 0.0 6.9 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH16176.1 - 5.3e-06 26.6 0.1 0.063 13.6 0.0 4.5 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 CEH16176.1 - 0.26 10.0 0.0 0.56 8.9 0.0 1.5 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 CEH16177.1 - 4.2e-10 40.1 18.8 0.0068 17.2 0.3 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH16177.1 - 0.00011 22.5 0.0 0.035 14.4 0.0 3.1 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CEH16177.1 - 0.079 13.5 0.2 0.63 10.6 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain GREB1 PF15782.5 CEH16179.1 - 2.2 5.3 3.9 3 4.9 3.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAP1 PF08601.10 CEH16179.1 - 5 6.7 10.1 8.3 6.0 10.1 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Tho1_MOS11_C PF18592.1 CEH16180.1 - 6.2e-08 32.3 16.8 1.8e-07 30.8 1.9 3.6 4 0 0 4 4 4 2 Tho1/MOS11 C-terminal domain SAP PF02037.27 CEH16180.1 - 0.00079 19.1 0.1 0.0019 17.9 0.1 1.7 1 0 0 1 1 1 1 SAP domain TEBP_beta PF07404.11 CEH16180.1 - 1.7 7.9 16.2 2.6 7.3 16.2 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) MDD_C PF18376.1 CEH16181.1 - 1e-68 230.8 0.0 1.5e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CEH16181.1 - 7.2e-06 26.2 4.5 7.2e-06 26.2 4.5 2.3 4 0 0 4 4 4 1 GHMP kinases N terminal domain Tegument_dsDNA PF12818.7 CEH16181.1 - 0.015 14.5 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein DUF2780 PF11075.8 CEH16181.1 - 0.14 12.3 5.2 0.22 11.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) RRM_1 PF00076.22 CEH16182.1 - 2.6e-13 49.6 0.0 1.6e-05 24.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adeno_PIX PF03955.14 CEH16182.1 - 0.0059 16.8 1.9 0.0059 16.8 1.9 2.8 4 0 0 4 4 4 1 Adenovirus hexon-associated protein (IX) RRM_7 PF16367.5 CEH16182.1 - 0.0087 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Inhibitor_I34 PF10466.9 CEH16182.1 - 0.45 11.1 3.1 1.4 9.5 3.1 1.8 1 0 0 1 1 1 0 Saccharopepsin inhibitor I34 DUF1275 PF06912.11 CEH16183.1 - 4.4e-25 88.7 11.7 7e-25 88.1 11.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Abhydrolase_9_N PF15420.6 CEH16183.1 - 0.07 13.1 0.1 0.07 13.1 0.1 3.2 2 1 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus DUF3010 PF11215.8 CEH16184.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3010) Cwf_Cwc_15 PF04889.12 CEH16186.1 - 8.6e-73 245.1 22.7 9.7e-73 244.9 22.7 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Menin PF05053.13 CEH16186.1 - 0.38 9.1 10.8 0.54 8.6 10.8 1.2 1 0 0 1 1 1 0 Menin Rax2 PF12768.7 CEH16187.1 - 1.5e-34 119.3 0.0 8.2e-33 113.7 0.0 3.6 4 0 0 4 4 4 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 CEH16187.1 - 5.3e-11 42.0 0.1 3.2e-10 39.4 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CEH16187.1 - 3.8e-09 36.3 0.0 9.6e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEH16187.1 - 0.0052 16.4 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.6 CEH16187.1 - 0.022 15.0 3.1 80 3.7 0.0 6.3 6 0 0 6 6 6 0 Kelch motif VirB3 PF05101.13 CEH16187.1 - 0.14 12.4 1.5 0.29 11.4 1.5 1.4 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein PQQ_3 PF13570.6 CEH16187.1 - 1.1 9.8 16.9 0.44 11.1 0.4 6.8 7 0 0 7 7 7 0 PQQ-like domain DUF3330 PF11809.8 CEH16188.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Suf PF05843.14 CEH16191.1 - 0.00014 22.0 7.0 0.051 13.6 0.4 4.8 4 1 0 5 5 5 2 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 CEH16191.1 - 0.00091 19.2 7.5 5 7.1 0.1 6.2 7 1 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 CEH16191.1 - 0.042 14.7 36.6 18 6.5 0.0 12.3 13 3 2 15 15 15 0 Tetratricopeptide repeat Endonuc_subdom PF09062.10 CEH16191.1 - 0.18 12.7 0.5 0.53 11.1 0.2 1.9 2 0 0 2 2 2 0 PI-PfuI Endonuclease subdomain TPR_8 PF13181.6 CEH16191.1 - 0.23 11.7 5.3 74 3.9 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEH16191.1 - 0.59 10.5 13.1 18 5.7 0.4 5.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEH16191.1 - 1.2 9.9 5.2 2.1e+02 2.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEH16191.1 - 3.4 8.2 15.1 1.1 9.8 0.9 6.5 8 1 0 9 9 9 0 Tetratricopeptide repeat HAT PF02184.16 CEH16191.1 - 5.2 7.1 20.2 4.8 7.2 0.3 6.8 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat TPR_2 PF07719.17 CEH16191.1 - 6.5 7.1 23.1 4.6 7.6 0.0 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat zf-U1 PF06220.12 CEH16192.1 - 2.2e-05 24.1 0.1 3.7e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger BMP2K_C PF15282.6 CEH16192.1 - 0.038 13.9 5.3 0.24 11.2 5.3 2.1 1 1 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus ATG22 PF11700.8 CEH16194.1 - 6.7e-126 420.7 18.1 7.9e-126 420.5 18.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 CEH16194.1 - 4.6e-10 39.0 34.5 0.00011 21.3 1.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily TRAM_LAG1_CLN8 PF03798.16 CEH16197.1 - 5.2e-45 153.6 13.8 8.1e-45 153.0 13.8 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 CEH16197.1 - 3.5e-10 39.4 0.0 3.5e-10 39.4 0.0 2.4 3 1 0 3 3 3 1 TRAM1-like protein Flu_C_NS2 PF03555.14 CEH16198.1 - 0.11 12.7 0.4 0.42 10.8 0.3 2.0 2 0 0 2 2 2 0 Influenza C non-structural protein (NS2) RR_TM4-6 PF06459.12 CEH16198.1 - 1.6 8.5 4.4 2 8.2 4.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Oxidored_q6 PF01058.22 CEH16199.1 - 4.4e-21 75.1 0.1 7.1e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit ANTH PF07651.16 CEH16200.1 - 3.2e-50 170.7 0.0 4.1e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 CEH16200.1 - 3.3e-07 30.4 0.0 6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 CEH16200.1 - 0.0053 17.1 44.0 0.0053 17.1 44.0 9.1 1 1 3 4 4 4 1 Domain of unknown function (DUF1720) VHS PF00790.19 CEH16200.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain MMS19_N PF14500.6 CEH16200.1 - 0.12 12.0 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Bax1-I PF01027.20 CEH16201.1 - 3.3e-37 128.3 24.7 3.8e-37 128.1 24.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 CEH16201.1 - 1.1e-07 31.7 5.5 1.5e-07 31.2 5.5 1.3 1 0 0 1 1 1 1 Bax inhibitor 1 like DUF2070 PF09843.9 CEH16201.1 - 7.2 4.8 16.8 9.5 4.4 16.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) OSCP PF00213.18 CEH16202.1 - 7.4e-37 127.1 0.1 8.8e-37 126.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit NAP PF00956.18 CEH16203.1 - 3e-98 328.3 4.1 4.3e-98 327.8 4.1 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Peptidase_C54 PF03416.19 CEH16204.1 - 2.2e-94 315.9 0.0 3e-94 315.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 PAC4 PF16093.5 CEH16205.1 - 0.08 13.1 0.1 0.35 11.1 0.1 2.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 SF3b1 PF08920.10 CEH16206.1 - 1.5e-30 106.1 0.6 1.5e-30 106.1 0.6 2.8 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 CEH16206.1 - 6e-12 45.8 13.3 0.001 19.4 0.1 8.4 4 2 5 9 9 9 4 HEAT repeats HEAT_EZ PF13513.6 CEH16206.1 - 7.6e-12 45.5 6.8 0.028 14.9 0.0 7.5 7 1 1 8 8 7 2 HEAT-like repeat Adaptin_N PF01602.20 CEH16206.1 - 2e-07 30.0 0.3 0.00035 19.3 0.2 4.1 1 1 1 2 2 2 1 Adaptin N terminal region HEAT PF02985.22 CEH16206.1 - 7.3e-07 28.9 9.6 0.96 9.9 0.1 8.7 10 0 0 10 10 9 1 HEAT repeat UME PF08064.13 CEH16206.1 - 9.8e-06 25.4 0.0 0.15 12.0 0.0 4.7 4 1 1 5 5 5 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 CEH16206.1 - 2.3e-05 24.9 1.4 2.2 8.9 0.0 5.0 6 0 0 6 6 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CEH16206.1 - 7e-05 22.9 5.7 3.8 7.5 0.0 6.1 6 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CEH16206.1 - 0.00012 21.7 1.3 0.051 13.1 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal NUC173 PF08161.12 CEH16206.1 - 0.00022 21.0 1.8 0.93 9.1 0.0 4.2 5 1 1 6 6 6 2 NUC173 domain MMS19_C PF12460.8 CEH16206.1 - 0.00023 20.4 0.0 0.12 11.5 0.0 3.7 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal TIP120 PF08623.10 CEH16206.1 - 0.00025 20.9 0.4 0.97 9.2 0.0 3.8 4 0 0 4 4 4 2 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 CEH16206.1 - 0.00082 19.3 0.6 4 7.3 0.0 4.1 4 1 0 4 4 4 2 Domain of unknown function (DUF3385) Dopey_N PF04118.14 CEH16206.1 - 0.006 15.7 0.5 0.19 10.8 0.0 3.1 3 0 0 3 3 3 1 Dopey, N-terminal LIDHydrolase PF10230.9 CEH16206.1 - 0.044 13.3 0.0 0.75 9.3 0.0 2.5 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DNA_pol_phi PF04931.13 CEH16206.1 - 0.14 10.3 0.0 3.5 5.6 0.0 2.4 1 1 0 1 1 1 0 DNA polymerase phi OS-D PF03392.13 CEH16207.1 - 0.055 13.6 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D DUF2340 PF10209.9 CEH16208.1 - 1.2e-40 138.6 0.2 1.5e-40 138.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 CEH16208.1 - 0.072 13.4 0.1 0.091 13.1 0.1 1.2 1 0 0 1 1 1 0 Blt1 N-terminal domain RNase_PH PF01138.21 CEH16209.1 - 7.2e-12 45.9 0.0 1.3e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF3412 PF11892.8 CEH16209.1 - 0.072 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) WW_FCH_linker PF16623.5 CEH16212.1 - 0.019 15.7 0.3 0.042 14.6 0.0 1.6 2 0 0 2 2 2 0 Unstructured linker region between on GAS7 protein FAD_binding_3 PF01494.19 CEH16213.1 - 4.1e-24 85.5 0.0 7.5e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CEH16213.1 - 5.9e-08 32.7 1.8 3.8e-05 23.4 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEH16213.1 - 7.7e-05 22.9 0.1 0.00021 21.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEH16213.1 - 0.00089 18.6 0.2 0.0017 17.6 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEH16213.1 - 0.0013 17.9 0.1 0.0017 17.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CEH16213.1 - 0.0021 18.6 0.1 0.052 14.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 CEH16213.1 - 0.0027 16.8 0.0 0.73 8.8 0.0 2.7 3 0 0 3 3 3 1 Squalene epoxidase HI0933_like PF03486.14 CEH16213.1 - 0.0067 15.2 0.5 0.013 14.2 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 CEH16213.1 - 0.032 13.1 0.5 5 5.8 0.2 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 CEH16213.1 - 0.037 13.3 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CEH16213.1 - 0.052 12.8 0.1 0.098 11.9 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 CEH16213.1 - 0.059 12.9 0.1 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 CEH16213.1 - 0.064 12.3 3.4 0.17 10.9 3.3 2.0 1 1 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 CEH16213.1 - 0.11 11.9 0.5 0.22 10.9 0.5 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CEH16213.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 CEH16213.1 - 0.19 11.4 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3721 PF12518.8 CEH16213.1 - 0.49 10.3 2.2 7.2 6.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function Pescadillo_N PF06732.11 CEH16214.1 - 1.5e-111 372.3 1.0 2.5e-111 371.6 0.0 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 CEH16214.1 - 0.00044 20.6 0.0 0.0026 18.1 0.0 2.2 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Adeno_E1A PF02703.14 CEH16214.1 - 0.05 13.2 0.8 0.085 12.4 0.8 1.3 1 0 0 1 1 1 0 Early E1A protein FAD_binding_4 PF01565.23 CEH16215.1 - 1.2e-26 93.1 1.8 2.6e-26 92.0 1.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CEH16215.1 - 1.5e-14 53.8 0.3 2.9e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF4766 PF15973.5 CEH16215.1 - 3.9 8.1 7.8 0.9 10.1 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) tRNA-synt_1b PF00579.25 CEH16216.1 - 9e-20 71.2 0.1 4.9e-19 68.8 0.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) F1F0-ATPsyn_F PF10791.9 CEH16217.1 - 2.8e-22 79.0 0.0 5e-22 78.2 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Iso_dh PF00180.20 CEH16218.1 - 5.4e-90 302.0 0.0 2.6e-89 299.8 0.0 1.8 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1447 PF07288.11 CEH16218.1 - 0.21 11.7 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) Ribosomal_S25 PF03297.15 CEH16220.1 - 6.5e-38 129.0 3.5 8.1e-38 128.7 3.5 1.1 1 0 0 1 1 1 1 S25 ribosomal protein DDRGK PF09756.9 CEH16220.1 - 0.037 13.6 1.2 0.065 12.8 1.1 1.4 1 1 0 1 1 1 0 DDRGK domain BioT2 PF15368.6 CEH16220.1 - 0.063 13.2 1.9 0.073 13.0 1.7 1.3 1 1 0 1 1 1 0 Spermatogenesis family BioT2 Mt_ATP-synt_D PF05873.12 CEH16221.1 - 9.4e-16 58.0 0.3 1.2e-15 57.7 0.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) RPW8 PF05659.11 CEH16221.1 - 0.0029 17.3 2.4 0.086 12.5 0.3 1.8 1 1 1 2 2 2 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 Peptidase_M17_N PF02789.17 CEH16221.1 - 0.017 15.0 1.2 0.031 14.1 0.1 1.8 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain TMPIT PF07851.13 CEH16221.1 - 0.018 14.3 1.4 0.022 14.0 1.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein JAKMIP_CC3 PF16034.5 CEH16221.1 - 0.019 14.9 0.8 0.022 14.7 0.8 1.1 1 0 0 1 1 1 0 JAKMIP CC3 domain Tropomyosin PF00261.20 CEH16221.1 - 0.024 14.0 3.6 1.5 8.1 0.5 2.1 2 0 0 2 2 2 0 Tropomyosin DUF2408 PF10303.9 CEH16221.1 - 0.032 14.8 3.0 0.14 12.7 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Prominin PF05478.11 CEH16221.1 - 0.046 11.7 0.2 0.052 11.5 0.2 1.0 1 0 0 1 1 1 0 Prominin Dor1 PF04124.12 CEH16221.1 - 0.054 12.2 1.7 0.059 12.1 1.7 1.1 1 0 0 1 1 1 0 Dor1-like family Con-6 PF10346.9 CEH16221.1 - 0.09 12.8 1.1 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Conidiation protein 6 Baculo_PEP_C PF04513.12 CEH16221.1 - 0.091 12.8 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus T3SS_needle_E PF08988.10 CEH16221.1 - 0.1 12.7 1.8 1.1 9.5 0.3 2.3 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Rx_N PF18052.1 CEH16221.1 - 0.26 11.6 3.5 2 8.7 0.4 2.3 1 1 1 2 2 2 0 Rx N-terminal domain DUF1366 PF07104.11 CEH16221.1 - 0.26 11.0 3.0 0.42 10.3 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1366) Syntaxin_2 PF14523.6 CEH16221.1 - 0.27 11.6 4.8 0.68 10.3 0.7 2.1 1 1 1 2 2 2 0 Syntaxin-like protein Spc24 PF08286.11 CEH16221.1 - 0.34 11.2 2.4 2.8 8.2 0.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 CEH16221.1 - 1.3 9.3 6.4 1.7 8.9 5.4 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 CEH16221.1 - 2.4 8.7 7.4 9.8 6.7 3.4 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Syntaxin PF00804.25 CEH16221.1 - 2.8 7.5 6.7 66 3.1 6.7 2.6 1 1 0 1 1 1 0 Syntaxin PBS_linker_poly PF00427.21 CEH16222.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Mating_N PF12731.7 CEH16224.1 - 0.14 12.2 0.3 0.5 10.5 0.2 1.8 1 1 0 2 2 2 0 Mating-type protein beta 1 ATP-sulfurylase PF01747.17 CEH16225.1 - 1e-86 289.8 0.1 1.5e-86 289.2 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 CEH16225.1 - 3.7e-56 189.4 0.0 5.5e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 CEH16225.1 - 7.9e-55 184.9 0.0 1.3e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain PH PF00169.29 CEH16226.1 - 4e-05 24.1 0.1 0.00043 20.8 0.0 2.5 3 0 0 3 3 3 1 PH domain AMPK1_CBM PF16561.5 CEH16227.1 - 4.9e-20 71.5 0.0 7.6e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_20 PF00686.19 CEH16227.1 - 0.043 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Starch binding domain Pkinase PF00069.25 CEH16228.1 - 3.4e-16 59.4 0.0 8.3e-14 51.6 0.0 2.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH16228.1 - 4.2e-05 22.9 0.0 0.00031 20.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CEH16228.1 - 0.0026 17.7 0.1 0.0059 16.6 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEH16228.1 - 0.039 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CEH16228.1 - 0.049 12.7 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GREB1 PF15782.5 CEH16228.1 - 0.19 8.9 5.7 0.27 8.3 5.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Bromodomain PF00439.25 CEH16230.1 - 4.2e-22 78.0 0.1 7.5e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CEH16230.1 - 3.6e-08 33.6 2.0 4.7e-08 33.3 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEH16230.1 - 1.9e-07 31.1 0.0 4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEH16230.1 - 0.00028 21.2 0.1 0.00057 20.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_M20 PF01546.28 CEH16232.1 - 1.4e-20 73.9 0.0 2.1e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 CEH16232.1 - 7.1e-15 55.2 14.0 1.3e-05 25.9 0.0 7.1 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.14 CEH16232.1 - 4.1e-09 36.3 0.0 7.6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Nucleoporin_N PF08801.11 CEH16232.1 - 1.1e-05 24.4 0.1 0.093 11.4 0.1 3.4 3 1 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 CEH16232.1 - 0.032 12.9 0.2 0.88 8.1 0.0 3.0 3 1 1 4 4 4 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CEH16232.1 - 0.047 14.0 0.0 11 6.4 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SecY PF00344.20 CEH16234.1 - 6e-70 235.9 7.4 7.3e-70 235.6 7.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CEH16234.1 - 1.7e-17 62.9 0.3 9.4e-17 60.6 0.3 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p CBM_4_9 PF02018.17 CEH16235.1 - 0.016 15.5 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain UPF0506 PF11703.8 CEH16235.1 - 0.92 9.9 34.5 5.9 7.4 12.4 3.2 3 1 0 3 3 3 0 UPF0506 EB PF01683.18 CEH16235.1 - 5 7.5 35.3 0.36 11.2 4.4 3.6 1 1 3 4 4 4 0 EB module zf-H2C2_2 PF13465.6 CEH16236.1 - 1.8e-12 47.1 15.5 2e-07 31.1 0.6 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CEH16236.1 - 1.1e-10 41.4 17.8 0.0025 18.2 3.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEH16236.1 - 7.7e-09 35.7 15.3 0.011 16.5 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CEH16236.1 - 6.9e-06 25.7 6.8 0.01 15.6 0.5 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CEH16236.1 - 5.8e-05 23.0 10.2 0.0039 17.1 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CEH16236.1 - 0.00096 19.5 5.1 1.7 9.1 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEH16236.1 - 0.0027 17.9 4.7 0.28 11.5 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding IBR PF01485.21 CEH16236.1 - 0.028 14.6 4.8 0.2 11.9 4.8 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_8 PF15909.5 CEH16236.1 - 0.093 13.0 2.0 0.25 11.7 2.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 CEH16236.1 - 0.19 12.2 5.6 11 6.6 1.4 2.8 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 CEH16236.1 - 0.21 11.7 3.9 0.12 12.5 1.5 1.9 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 CEH16236.1 - 0.24 11.4 3.7 4.6 7.3 0.2 2.6 1 1 1 2 2 2 0 BED zinc finger zf_UBZ PF18439.1 CEH16236.1 - 0.5 10.0 1.6 11 5.7 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 CEH16236.1 - 0.63 10.1 3.1 14 5.8 0.3 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zf-trcl PF13451.6 CEH16236.1 - 0.84 9.6 3.7 2.5 8.1 0.2 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain C1_4 PF07975.12 CEH16236.1 - 1.1 9.6 3.9 3.1 8.1 3.7 1.9 1 1 1 2 2 2 0 TFIIH C1-like domain zf-AN1 PF01428.16 CEH16236.1 - 3.9 7.7 7.2 6.6 7.0 2.8 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger Pkinase PF00069.25 CEH16237.1 - 8.9e-30 103.9 0.0 1.3e-24 87.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CEH16237.1 - 1.6e-14 53.8 0.0 3.3e-12 46.3 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CEH16237.1 - 2e-08 33.9 0.0 3.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEH16237.1 - 0.0014 18.0 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosom_S12_S23 PF00164.25 CEH16238.1 - 3.2e-49 165.3 0.8 4e-49 165.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L27e PF01777.18 CEH16239.1 - 5e-33 113.3 0.7 6.3e-33 113.0 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CEH16239.1 - 0.089 12.8 0.5 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 KOW motif SNF2_N PF00176.23 CEH16240.1 - 2.3e-69 233.8 0.0 3.2e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 CEH16240.1 - 5.7e-21 74.2 0.0 1.8e-20 72.7 0.0 1.9 2 0 0 2 2 2 1 HIRAN domain Helicase_C PF00271.31 CEH16240.1 - 1.6e-15 57.4 0.0 4.5e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 CEH16240.1 - 5.7e-05 22.9 13.8 0.0001 22.1 13.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEH16240.1 - 0.00012 21.9 16.6 0.00021 21.1 16.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 CEH16240.1 - 0.00032 20.8 0.0 0.32 11.0 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 CEH16240.1 - 0.013 15.3 16.5 0.028 14.2 16.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEH16240.1 - 0.015 15.6 15.6 0.028 14.8 15.6 1.4 1 0 0 1 1 1 0 Ring finger domain AAA_34 PF13872.6 CEH16240.1 - 0.024 13.5 0.0 0.053 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-RING_5 PF14634.6 CEH16240.1 - 0.067 13.2 15.9 0.12 12.4 15.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEH16240.1 - 1.4 9.0 12.9 3.1 7.9 12.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger RNase_T PF00929.24 CEH16241.1 - 3.6e-20 73.2 0.0 4.9e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease AalphaY_MDB PF04611.12 CEH16241.1 - 0.096 12.7 0.1 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region DUF3552 PF12072.8 CEH16242.1 - 0.00031 20.2 3.4 0.00031 20.2 3.4 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3552) Pectinesterase PF01095.19 CEH16246.1 - 3.9e-07 29.1 0.1 7.2e-07 28.2 0.1 1.5 1 1 0 1 1 1 1 Pectinesterase Glyco_hydro_92 PF07971.12 CEH16247.1 - 2.4e-118 396.0 0.1 3.5e-118 395.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 CEH16247.1 - 5.6e-34 118.1 0.2 8.4e-34 117.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DUF3844 PF12955.7 CEH16248.1 - 7.3e-27 93.6 3.3 1.2e-26 92.9 3.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) PX PF00787.24 CEH16249.1 - 1.1e-23 83.3 0.2 1.7e-23 82.7 0.2 1.3 1 0 0 1 1 1 1 PX domain LysM PF01476.20 CEH16251.1 - 1.3e-05 25.1 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 LysM domain Ras PF00071.22 CEH16252.1 - 1.4e-46 158.0 0.5 1.9e-46 157.6 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH16252.1 - 2.4e-17 63.3 0.0 5e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH16252.1 - 7.1e-08 32.1 0.0 9.7e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEH16252.1 - 5.7e-06 26.3 0.0 0.008 16.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CEH16252.1 - 8e-06 25.5 0.4 4.1e-05 23.2 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEH16252.1 - 8.6e-05 22.6 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH16252.1 - 0.00023 20.7 0.1 0.0037 16.8 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 CEH16252.1 - 0.00052 19.5 0.0 0.00072 19.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 CEH16252.1 - 0.014 15.4 0.1 0.034 14.2 0.1 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 CEH16252.1 - 0.15 12.4 0.0 0.26 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain zn-ribbon_14 PF16503.5 CEH16253.1 - 1.2e-16 59.8 4.1 1.2e-16 59.8 4.1 2.2 2 0 0 2 2 2 1 Zinc-ribbon ATP_bind_3 PF01171.20 CEH16253.1 - 1.9e-14 53.9 0.0 2.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 CEH16253.1 - 0.2 11.3 4.9 0.076 12.6 1.1 2.2 2 0 0 2 2 2 0 RecR protein Pkinase PF00069.25 CEH16254.1 - 8.7e-64 215.4 0.0 1.2e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH16254.1 - 1.2e-35 123.1 0.0 2.2e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH16254.1 - 6.9e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEH16254.1 - 0.039 13.9 6.0 0.17 11.7 0.1 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3584 PF12128.8 CEH16254.1 - 3.7 4.9 17.3 6.1 4.2 17.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Macoilin PF09726.9 CEH16254.1 - 4 5.9 10.0 8.7 4.8 10.0 1.6 1 0 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 CEH16254.1 - 6.8 6.2 12.2 9.5 5.7 11.5 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit MCM PF00493.23 CEH16256.1 - 2.2e-97 324.5 0.2 3.5e-97 323.9 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEH16256.1 - 4.7e-33 113.7 0.0 8.6e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEH16256.1 - 6.9e-24 84.1 0.5 1.4e-23 83.1 0.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CEH16256.1 - 1.4e-15 57.8 0.0 4e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CEH16256.1 - 8.8e-08 31.8 0.0 1.4e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEH16256.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEH16256.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sporozoite_P67 PF05642.11 CEH16256.1 - 0.094 10.8 0.5 0.14 10.3 0.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRM_1 PF00076.22 CEH16257.1 - 3.8e-32 109.9 0.0 3.4e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEH16257.1 - 0.0006 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CEH16257.1 - 0.0036 16.9 0.0 0.014 15.0 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 CEH16258.1 - 1.9e-20 73.1 14.5 1.9e-20 73.1 14.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CEH16258.1 - 0.045 12.6 2.0 0.046 12.6 1.0 1.4 1 1 0 1 1 1 0 MFS_1 like family Aminotran_3 PF00202.21 CEH16260.1 - 9.2e-80 268.3 0.0 1.1e-79 268.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III 2-Hacid_dh_C PF02826.19 CEH16262.1 - 3.3e-44 150.4 0.0 5.5e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEH16262.1 - 6.5e-23 80.9 0.0 8.2e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 CEH16262.1 - 0.0091 15.3 0.0 1.9 7.7 0.0 2.3 1 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 CEH16262.1 - 0.012 15.7 0.0 0.09 12.8 0.0 2.3 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HMMR_C PF15908.5 CEH16263.1 - 0.018 15.3 4.1 0.018 15.3 4.1 4.5 2 1 2 5 5 5 0 Hyaluronan mediated motility receptor C-terminal HORMA PF02301.18 CEH16263.1 - 1.6 8.3 9.2 0.2 11.2 0.6 2.8 3 0 0 3 3 3 0 HORMA domain GAS PF13851.6 CEH16263.1 - 6.6 6.0 75.2 3.6 6.9 32.5 5.8 2 2 3 5 5 5 0 Growth-arrest specific micro-tubule binding APH PF01636.23 CEH16264.1 - 2.6e-19 70.1 0.0 5.5e-19 69.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family CAP_GLY PF01302.25 CEH16265.1 - 1.2e-15 57.2 0.3 2.1e-15 56.5 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 CEH16265.1 - 4.8e-06 26.3 3.9 1.1e-05 25.2 3.9 1.6 1 0 0 1 1 1 1 CLIP1 zinc knuckle DUF4201 PF13870.6 CEH16265.1 - 0.0066 16.2 4.3 0.0066 16.2 4.3 6.3 4 3 2 6 6 6 1 Domain of unknown function (DUF4201) THOC7 PF05615.13 CEH16265.1 - 0.017 15.4 0.4 0.017 15.4 0.4 7.9 3 2 3 6 6 6 0 Tho complex subunit 7 Filament PF00038.21 CEH16265.1 - 0.019 14.5 0.6 0.019 14.5 0.6 5.6 2 2 2 4 4 4 0 Intermediate filament protein CBFD_NFYB_HMF PF00808.23 CEH16266.1 - 3.1e-12 46.6 0.2 6.6e-12 45.5 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEH16266.1 - 0.0058 17.0 2.6 0.017 15.5 2.6 2.0 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CEH16266.1 - 0.0092 16.1 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Herpes_Helicase PF02689.14 CEH16266.1 - 0.05 11.5 0.0 0.059 11.3 0.0 1.1 1 0 0 1 1 1 0 Helicase Telomerase_RBD PF12009.8 CEH16267.1 - 7.2e-37 126.5 0.0 1.6e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CEH16267.1 - 8.3e-13 48.4 0.0 3.5e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0489 PF12640.7 CEH16269.1 - 0.003 17.8 0.1 0.003 17.8 0.1 1.2 1 0 0 1 1 1 1 UPF0489 domain HSF_DNA-bind PF00447.17 CEH16270.1 - 7.3e-31 106.6 0.5 1.2e-30 106.0 0.5 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Macoilin PF09726.9 CEH16270.1 - 0.036 12.6 0.3 0.049 12.2 0.3 1.2 1 0 0 1 1 1 0 Macoilin family Ferric_reduct PF01794.19 CEH16271.1 - 4.2e-17 62.4 9.3 2e-16 60.2 9.3 2.2 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CEH16271.1 - 1.1e-14 54.4 0.0 1.1e-09 38.4 0.1 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 CEH16271.1 - 6.3e-07 29.6 0.0 0.0054 16.9 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain GGDEF_2 PF17853.1 CEH16271.1 - 0.027 14.7 0.9 0.49 10.7 1.0 2.8 2 1 0 2 2 2 0 GGDEF-like domain Pkinase PF00069.25 CEH16272.1 - 5.8e-48 163.6 0.0 8.2e-47 159.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH16272.1 - 2e-23 83.0 0.0 1.2e-17 64.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase adh_short_C2 PF13561.6 CEH16273.1 - 1.3e-40 139.5 0.5 1.7e-40 139.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH16273.1 - 1.3e-29 103.1 0.1 1.8e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH16273.1 - 9.5e-06 25.6 0.1 1.4e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1748 PF08520.10 CEH16275.1 - 8e-21 73.7 0.1 9e-21 73.6 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PRKCSH-like PF12999.7 CEH16276.1 - 1.4e-49 168.2 6.4 2.2e-49 167.6 5.3 1.9 1 1 1 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CEH16276.1 - 7.1e-22 77.7 0.0 1.5e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CEH16276.1 - 3.5e-10 40.7 0.4 9.2e-10 39.4 0.4 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein RabGAP-TBC PF00566.18 CEH16277.1 - 3.1e-16 59.7 0.0 7.7e-16 58.4 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PBECR5 PF18814.1 CEH16277.1 - 0.01 15.8 0.0 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 EPSP_synthase PF00275.20 CEH16278.1 - 9e-124 413.3 0.0 1.3e-123 412.8 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CEH16278.1 - 5.4e-95 317.5 1.1 1.1e-94 316.5 0.0 2.1 3 0 0 3 3 3 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CEH16278.1 - 5.7e-50 170.7 0.0 1e-49 169.8 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CEH16278.1 - 2.5e-25 89.4 0.0 2.8e-24 86.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 CEH16278.1 - 3.9e-24 84.7 0.0 1.1e-23 83.2 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 CEH16278.1 - 9.1e-06 25.3 0.7 3.8e-05 23.4 0.1 2.4 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 CEH16278.1 - 2.2e-05 24.3 0.9 5.7e-05 22.9 0.9 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 CEH16278.1 - 0.00012 22.2 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 CEH16278.1 - 0.084 13.0 0.1 15 5.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain Pkinase PF00069.25 CEH16279.1 - 1.4e-45 155.7 0.0 4.8e-34 117.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH16279.1 - 2.9e-16 59.5 0.0 2e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CEH16279.1 - 0.0051 16.8 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEH16279.1 - 0.0059 16.0 0.0 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEH16279.1 - 0.016 14.0 0.0 0.03 13.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 CEH16279.1 - 0.02 13.9 0.0 0.14 11.1 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 CEH16279.1 - 0.022 14.1 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease PF00324.21 CEH16280.1 - 8e-119 397.4 42.9 9.1e-119 397.2 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEH16280.1 - 8.4e-33 113.8 44.6 1.1e-32 113.4 44.4 1.3 1 1 0 1 1 1 1 Amino acid permease Polysacc_deac_1 PF01522.21 CEH16282.1 - 3.3e-24 85.1 0.0 6.7e-24 84.2 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase FAD_binding_7 PF03441.14 CEH16283.1 - 1.4e-53 181.4 0.3 2e-53 180.9 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CEH16283.1 - 3.4e-19 69.4 0.0 6.6e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase RCR PF12273.8 CEH16284.1 - 8.6e-07 29.6 10.0 8.6e-07 29.6 10.0 2.3 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.10 CEH16284.1 - 0.0029 17.0 0.9 0.004 16.5 0.9 1.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Prominin PF05478.11 CEH16284.1 - 0.12 10.3 0.0 0.16 9.9 0.0 1.0 1 0 0 1 1 1 0 Prominin Josephin PF02099.17 CEH16285.1 - 5.7e-46 156.6 0.0 1.5e-45 155.2 0.0 1.7 1 0 0 1 1 1 1 Josephin UIM PF02809.20 CEH16285.1 - 0.0039 17.0 3.7 0.0039 17.0 3.7 5.2 4 0 0 4 4 4 2 Ubiquitin interaction motif SelK_SelG PF10961.8 CEH16285.1 - 4.4 8.0 7.3 62 4.3 5.8 3.4 3 0 0 3 3 3 0 Selenoprotein SelK_SelG Skp1_POZ PF03931.15 CEH16287.1 - 3e-08 33.7 0.0 4.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain adh_short PF00106.25 CEH16288.1 - 6.8e-07 28.9 0.1 0.0082 15.6 0.0 3.4 3 1 0 3 3 3 2 short chain dehydrogenase Phage_tail_APC PF16778.5 CEH16288.1 - 0.05 13.5 0.1 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 Phage tail assembly chaperone protein SIMPL PF04402.14 CEH16292.1 - 1.1e-24 88.1 3.1 1.2e-24 87.9 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Npun_R1517 PF18068.1 CEH16292.1 - 0.022 15.0 0.1 4.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Npun R1517 DUF1357 PF07094.11 CEH16292.1 - 0.045 13.8 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) Arrestin_N PF00339.29 CEH16293.1 - 0.07 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain SIR2 PF02146.17 CEH16294.1 - 1.7e-30 106.3 0.0 2.4e-29 102.5 0.0 2.1 1 1 0 1 1 1 1 Sir2 family MMR_HSR1 PF01926.23 CEH16296.1 - 3e-11 43.4 0.0 7.2e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEH16296.1 - 0.005 16.8 0.6 0.33 10.8 0.2 2.7 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 CEH16296.1 - 0.026 14.1 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 CEH16296.1 - 0.11 12.8 1.1 1.5 9.2 0.2 2.9 2 0 0 2 2 2 0 AAA ATPase domain IIGP PF05049.13 CEH16296.1 - 0.28 10.2 0.1 0.48 9.4 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 CEH16296.1 - 0.28 11.2 1.7 0.66 10.0 0.2 2.4 3 0 0 3 3 3 0 Dynamin family Not3 PF04065.15 CEH16297.1 - 3.7e-88 294.8 18.7 5.2e-88 294.4 18.7 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CEH16297.1 - 4.3e-36 123.9 8.9 1.5e-35 122.1 8.9 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Glyco_hydro_67C PF07477.12 CEH16297.1 - 0.054 13.0 0.6 0.096 12.2 0.6 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus DUF2203 PF09969.9 CEH16297.1 - 1.7 9.4 10.3 2.1 9.1 3.8 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) HIP1_clath_bdg PF16515.5 CEH16297.1 - 5.7 7.6 18.4 1.9 9.1 8.1 3.1 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UBA PF00627.31 CEH16298.1 - 9.9e-22 76.5 5.6 2.2e-14 53.0 0.1 2.9 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 CEH16298.1 - 4.7e-21 74.3 0.3 7.2e-21 73.7 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 CEH16298.1 - 4e-17 61.7 6.8 7.5e-17 60.8 6.8 1.4 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 CEH16298.1 - 5e-07 29.5 0.6 1.5e-06 28.0 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 CEH16298.1 - 0.00011 22.0 0.0 0.0055 16.5 0.0 2.7 2 0 0 2 2 2 1 UBA-like domain CUE PF02845.16 CEH16298.1 - 0.00096 18.8 1.1 1.1 9.0 0.0 3.8 3 1 1 4 4 4 1 CUE domain Rad60-SLD_2 PF13881.6 CEH16298.1 - 0.0028 17.8 0.1 0.0064 16.6 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Metal_resist PF13801.6 CEH16298.1 - 0.0067 16.6 13.0 0.14 12.3 6.8 3.5 3 1 1 4 4 4 1 Heavy-metal resistance HBS1_N PF08938.10 CEH16298.1 - 0.04 14.2 0.1 11 6.4 0.1 2.6 2 0 0 2 2 2 0 HBS1 N-terminus DUF2407 PF10302.9 CEH16298.1 - 0.056 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UBA_3 PF09288.10 CEH16298.1 - 0.11 12.3 0.0 24 4.8 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Ubiquitin_2 PF14560.6 CEH16298.1 - 0.22 12.0 0.1 0.43 11.1 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain FSA_C PF10479.9 CEH16298.1 - 1.6 6.8 7.9 2.1 6.4 7.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus STI1 PF17830.1 CEH16298.1 - 3.9 7.5 7.5 14 5.7 0.5 3.1 3 1 1 4 4 3 0 STI1 domain p450 PF00067.22 CEH16299.1 - 3.7e-77 260.0 0.0 2.3e-76 257.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 PAP_PilO PF06864.12 CEH16299.1 - 0.051 12.4 0.3 0.089 11.6 0.3 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) ATG27 PF09451.10 CEH16300.1 - 1.1e-38 133.6 0.0 1.6e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 CEH16300.1 - 0.0013 18.8 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat Sulf_transp PF04143.14 CEH16300.1 - 0.058 13.0 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Sulphur transport NACHT_N PF17100.5 CEH16301.1 - 0.016 15.1 1.3 0.02 14.8 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase Raftlin PF15250.6 CEH16301.1 - 0.89 8.2 2.7 1.4 7.6 2.7 1.3 1 0 0 1 1 1 0 Raftlin GREB1 PF15782.5 CEH16301.1 - 6.3 3.8 8.1 8.3 3.4 8.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4385 PF14328.6 CEH16302.1 - 3.2e-55 186.2 0.1 3.2e-55 186.2 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4385) ParA PF10609.9 CEH16303.1 - 3.3e-67 226.5 0.0 8.5e-67 225.2 0.0 1.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CEH16303.1 - 9.8e-09 35.3 0.0 2.1e-07 31.0 0.0 2.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CEH16303.1 - 6.9e-06 26.1 3.5 0.026 14.4 1.0 2.2 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 CEH16303.1 - 3.3e-05 23.2 8.3 0.0004 19.7 2.1 2.9 2 1 1 3 3 3 2 Anion-transporting ATPase MipZ PF09140.11 CEH16303.1 - 0.0031 16.8 0.6 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 CEH16303.1 - 0.0041 16.7 0.4 0.0078 15.8 0.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 CEH16303.1 - 0.2 11.4 1.7 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 CEH16303.1 - 5.9 6.3 5.7 3.9 6.8 0.2 2.8 3 1 0 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family GFO_IDH_MocA PF01408.22 CEH16304.1 - 3.5e-14 53.7 0.0 1.6e-13 51.5 0.0 2.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SHE3 PF17078.5 CEH16304.1 - 3.5e-08 33.5 15.1 5.5e-08 32.8 15.1 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 BBP1_C PF15272.6 CEH16304.1 - 0.084 12.7 9.9 0.082 12.7 8.7 1.6 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF5339 PF17274.2 CEH16304.1 - 4.8 8.1 11.9 27 5.7 0.6 4.1 3 0 0 3 3 3 0 Family of unknown function (DUF5339) DHR10 PF18595.1 CEH16304.1 - 5 7.2 35.0 5.5 7.1 11.1 3.0 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF2951 PF11166.8 CEH16304.1 - 5.8 7.2 7.6 5.9 7.2 1.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) DUF5344 PF17279.2 CEH16304.1 - 5.8 7.6 8.6 11 6.6 0.3 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5344) SPC22 PF04573.12 CEH16305.1 - 1.3e-44 151.7 0.3 1.5e-44 151.5 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit RINT1_TIP1 PF04437.13 CEH16305.1 - 0.023 13.6 0.1 0.029 13.3 0.1 1.1 1 0 0 1 1 1 0 RINT-1 / TIP-1 family BolA PF01722.18 CEH16306.1 - 8e-30 103.0 0.3 9.1e-30 102.8 0.3 1.0 1 0 0 1 1 1 1 BolA-like protein WD40 PF00400.32 CEH16307.1 - 6.8e-15 55.2 4.5 5.1e-06 27.1 0.1 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH16307.1 - 3e-06 27.5 0.4 0.3 11.4 0.0 4.8 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Aldo_ket_red PF00248.21 CEH16308.1 - 3.1e-64 217.0 0.0 3.5e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SPAM PF02090.15 CEH16309.1 - 0.024 14.5 4.4 0.042 13.6 4.4 1.3 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DnaJ PF00226.31 CEH16310.1 - 8.1e-18 64.3 0.3 2.9e-17 62.5 0.1 2.2 2 0 0 2 2 1 1 DnaJ domain TPR_2 PF07719.17 CEH16310.1 - 4.9e-17 60.6 22.2 0.0049 16.9 0.1 7.7 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 CEH16310.1 - 5.6e-16 58.9 25.6 4.8e-09 36.7 2.0 5.9 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 CEH16310.1 - 8.8e-16 57.0 15.8 0.00059 19.6 0.1 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 CEH16310.1 - 5.4e-15 55.7 29.0 1.8e-06 28.4 1.9 6.0 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEH16310.1 - 2.3e-12 46.4 10.2 0.0025 18.1 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEH16310.1 - 6.6e-12 44.7 10.8 0.075 13.3 0.1 6.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEH16310.1 - 1.8e-11 43.9 24.9 0.00081 20.0 1.1 7.4 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 CEH16310.1 - 1e-10 41.6 17.6 1.8e-06 28.0 0.3 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEH16310.1 - 4.3e-10 39.1 7.5 0.00035 20.2 0.1 5.1 4 1 1 5 5 5 3 TPR repeat Fis1_TPR_C PF14853.6 CEH16310.1 - 1.1e-08 35.0 16.0 0.036 14.1 0.2 7.3 6 2 2 8 8 8 3 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CEH16310.1 - 6.1e-06 26.4 9.7 0.025 14.8 0.3 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF5113 PF17140.4 CEH16310.1 - 0.0038 17.1 1.6 0.054 13.3 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF5113) TPR_20 PF14561.6 CEH16310.1 - 0.0047 17.2 15.8 0.44 10.9 0.2 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEH16310.1 - 0.0066 17.0 16.0 0.55 11.0 0.2 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat Cytochrom_B562 PF07361.11 CEH16310.1 - 0.042 14.5 0.9 0.042 14.5 0.9 3.9 4 1 0 4 4 4 0 Cytochrome b562 TPR_4 PF07721.14 CEH16310.1 - 0.082 13.6 13.6 3.9 8.4 3.5 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 CEH16310.1 - 0.45 11.0 16.4 0.8 10.1 0.5 4.7 2 2 2 5 5 5 0 Bacterial transcriptional activator domain TPR_12 PF13424.6 CEH16310.1 - 2 8.8 18.4 2.7 8.4 1.3 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat YfiO PF13525.6 CEH16310.1 - 4.8 6.9 9.6 0.31 10.8 0.6 3.2 3 2 1 4 4 3 0 Outer membrane lipoprotein DUF2428 PF10350.9 CEH16311.1 - 1.9e-58 197.9 0.1 3.4e-58 197.1 0.1 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) PIGA PF08288.12 CEH16311.1 - 1.3e-40 137.8 0.2 3.7e-40 136.4 0.2 1.9 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CEH16311.1 - 2.5e-29 102.4 2.1 2.5e-29 102.4 2.1 2.2 2 0 0 2 2 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CEH16311.1 - 9.5e-23 80.6 0.0 1.9e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEH16311.1 - 1.4e-19 70.9 0.0 3.6e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CEH16311.1 - 2.7e-14 53.9 0.5 2.7e-14 53.9 0.5 4.2 4 0 0 4 4 3 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CEH16311.1 - 2.2e-06 27.7 0.0 4.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CEH16311.1 - 0.00083 19.7 0.1 0.0036 17.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 HEAT PF02985.22 CEH16311.1 - 0.0015 18.6 16.2 0.48 10.8 0.0 7.5 9 1 0 9 9 6 1 HEAT repeat Vac14_Fab1_bd PF12755.7 CEH16311.1 - 0.084 13.5 0.0 6.2 7.5 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Arm PF00514.23 CEH16311.1 - 0.11 12.6 0.0 4.4 7.5 0.0 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 CEH16311.1 - 0.22 10.1 1.1 1.1 7.7 0.0 2.4 2 1 1 3 3 3 0 Adaptin N terminal region HEAT_2 PF13646.6 CEH16311.1 - 0.35 11.3 17.1 0.28 11.6 0.2 6.0 6 1 2 8 8 6 0 HEAT repeats HEAT_EZ PF13513.6 CEH16311.1 - 0.51 10.9 8.6 1.7 9.3 0.0 4.8 3 0 0 3 3 3 0 HEAT-like repeat NUP50 PF08911.11 CEH16312.1 - 0.0015 19.1 0.2 0.0015 19.1 0.2 5.6 6 1 0 6 6 6 1 NUP50 (Nucleoporin 50 kDa) Oxysterol_BP PF01237.18 CEH16313.1 - 3.7e-121 404.5 0.0 7.5e-121 403.5 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 CEH16313.1 - 6.4e-11 42.7 0.0 1.2e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 CEH16313.1 - 1.1e-10 40.7 0.0 0.017 15.6 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 CEH16313.1 - 3.6e-10 39.8 0.1 7.3e-05 23.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CEH16313.1 - 4.4e-09 36.4 0.0 9.6e-06 25.8 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEH16313.1 - 4.7e-09 36.6 0.0 8.8e-05 23.0 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEH16313.1 - 4.9e-09 36.6 0.1 2.5e-06 28.0 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PH_11 PF15413.6 CEH16313.1 - 1.2e-05 25.7 0.1 3.3e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CEH16313.1 - 0.0048 17.1 0.1 0.012 15.8 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEAD_assoc PF08494.11 CEH16313.1 - 0.1 12.4 4.7 0.087 12.6 1.4 2.2 2 0 0 2 2 2 0 DEAD/H associated WcbI PF18588.1 CEH16313.1 - 0.4 10.3 2.2 1 9.0 2.2 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI Glyco_hydro_3_C PF01915.22 CEH16315.1 - 2.3e-42 145.3 0.0 3.6e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CEH16315.1 - 3.5e-39 135.1 0.0 6.3e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CEH16315.1 - 1.6e-26 92.2 0.2 3.7e-26 91.0 0.2 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain C2 PF00168.30 CEH16316.1 - 6.5e-14 52.1 0.0 3.5e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain NT-C2 PF10358.9 CEH16316.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins MBF1 PF08523.10 CEH16316.1 - 0.14 12.6 0.1 0.38 11.2 0.1 1.7 1 0 0 1 1 1 0 Multiprotein bridging factor 1 5_nucleotid_C PF02872.18 CEH16317.1 - 9.3e-33 113.7 0.0 1.2e-24 87.4 0.0 2.8 3 0 0 3 3 3 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CEH16317.1 - 3.5e-07 30.9 0.0 5.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 CEH16318.1 - 8.2e-28 97.3 29.0 8.2e-28 97.3 29.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DNA_processg_A PF02481.15 CEH16318.1 - 0.0066 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 DNA recombination-mediator protein A SNF2_N PF00176.23 CEH16319.1 - 1.2e-53 182.1 0.0 2.1e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEH16319.1 - 2.6e-17 63.2 0.3 7.4e-17 61.7 0.3 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH16319.1 - 6.2e-11 42.6 0.0 1.4e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CEH16319.1 - 1.2e-08 34.5 0.1 2.8e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 CEH16319.1 - 5.8e-05 22.1 0.0 0.00012 21.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 EMG1 PF03587.14 CEH16320.1 - 9.6e-77 257.0 0.0 1.2e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase HMG_box PF00505.19 CEH16321.1 - 1.6e-15 57.3 0.6 1.6e-15 57.3 0.6 2.5 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEH16321.1 - 3e-12 47.0 0.7 3e-12 47.0 0.7 2.1 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.13 CEH16321.1 - 0.058 13.9 1.1 0.058 13.9 1.1 2.1 2 1 0 3 3 3 0 YABBY protein Metal_resist PF13801.6 CEH16321.1 - 1.5 9.0 14.2 0.73 10.0 3.1 3.3 3 1 0 3 3 3 0 Heavy-metal resistance Snf7 PF03357.21 CEH16322.1 - 8.5e-42 142.7 16.0 8.5e-42 142.7 16.0 2.0 1 1 0 2 2 2 1 Snf7 SBDS_C PF09377.10 CEH16322.1 - 0.17 11.9 3.4 0.32 11.0 3.4 1.5 1 1 0 1 1 1 0 SBDS protein C-terminal domain Vps54_N PF10475.9 CEH16322.1 - 0.22 10.8 5.0 0.54 9.5 4.7 1.7 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex CTP_transf_like PF01467.26 CEH16323.1 - 5.1e-25 88.3 0.0 7.7e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_binding_1 PF00667.20 CEH16324.1 - 1.1e-55 188.7 0.0 1.5e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CEH16324.1 - 1e-07 32.6 0.0 2.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 CEH16324.1 - 1.4e-06 28.6 0.0 5.2e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II FAD_binding_6 PF00970.24 CEH16324.1 - 0.038 14.3 0.0 0.57 10.6 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain NAD_kinase PF01513.21 CEH16328.1 - 4.3e-58 196.8 0.0 9.4e-58 195.7 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CEH16328.1 - 0.0095 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain zf-rbx1 PF12678.7 CEH16329.1 - 1.1e-25 89.7 13.1 1.7e-25 89.1 13.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CEH16329.1 - 2.3e-17 62.8 12.0 2.9e-17 62.5 12.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CEH16329.1 - 1.8e-06 28.2 17.0 0.0001 22.5 17.0 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEH16329.1 - 0.00041 20.2 12.2 0.0043 16.9 12.2 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEH16329.1 - 0.00067 19.5 15.3 0.054 13.3 15.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEH16329.1 - 0.021 14.6 11.6 0.1 12.4 4.9 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEH16329.1 - 0.28 10.9 15.2 0.085 12.5 5.3 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CEH16329.1 - 0.29 11.2 8.2 1.3 9.1 8.2 2.2 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 CEH16329.1 - 0.31 11.2 14.0 0.089 13.0 9.2 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.6 CEH16329.1 - 1.4 8.9 12.2 7.5 6.6 12.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CEH16329.1 - 5.2 7.3 9.3 0.36 11.0 0.7 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CEH16329.1 - 6 6.7 21.2 43 4.0 17.0 2.7 2 1 0 2 2 2 0 RING-like zinc finger DUF3325 PF11804.8 CEH16330.1 - 6.8 6.9 6.5 1.1 9.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) LRR_4 PF12799.7 CEH16331.1 - 4.5e-09 36.4 23.7 0.00052 20.4 10.8 4.8 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEH16331.1 - 1.5e-07 31.0 21.5 0.0002 21.0 10.4 3.7 2 1 0 3 3 3 2 Leucine rich repeat Herpes_LP PF03363.13 CEH16331.1 - 0.011 15.5 0.8 0.011 15.5 0.8 2.2 2 0 0 2 2 2 0 Herpesvirus leader protein LRR_9 PF14580.6 CEH16331.1 - 0.19 11.2 2.6 0.52 9.8 2.6 1.7 1 1 0 1 1 1 0 Leucine-rich repeat Arrestin_N PF00339.29 CEH16332.1 - 5.2e-05 23.3 0.1 0.00051 20.1 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain BPS1 PF05633.11 CEH16332.1 - 0.12 11.4 0.4 0.2 10.6 0.4 1.3 1 0 0 1 1 1 0 Protein BYPASS1-related PRA1 PF03208.19 CEH16333.1 - 2.3e-35 121.3 0.3 2.7e-35 121.1 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein PALP PF00291.25 CEH16334.1 - 8.4e-78 261.8 0.6 1.2e-77 261.3 0.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CEH16334.1 - 1.5e-36 124.0 0.0 1.1e-22 79.6 0.0 3.0 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase Peripla_BP_6 PF13458.6 CEH16334.1 - 0.054 13.1 0.3 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Periplasmic binding protein AMMECR1 PF01871.17 CEH16335.1 - 2.1e-48 164.1 0.0 2.4e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 MHYT PF03707.16 CEH16337.1 - 1.3e-13 50.9 23.1 2.9e-06 27.3 2.8 4.8 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat Peptidase_A22B PF04258.13 CEH16337.1 - 0.007 15.9 1.2 0.014 14.9 1.2 1.4 1 0 0 1 1 1 1 Signal peptide peptidase Saf_2TM PF18303.1 CEH16337.1 - 0.069 12.7 2.1 2.4 7.8 0.2 2.7 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF2890 PF11081.8 CEH16337.1 - 0.085 13.0 5.8 0.25 11.4 5.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Transgly_assoc PF04226.13 CEH16337.1 - 0.57 10.5 7.8 1.8 8.9 7.8 1.8 1 0 0 1 1 1 0 Transglycosylase associated protein SNF2_N PF00176.23 CEH16338.1 - 4.1e-61 206.6 0.2 6.5e-61 206.0 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 CEH16338.1 - 2.2e-21 76.1 0.3 1.3e-20 73.6 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 CEH16338.1 - 3.6e-19 68.4 2.2 8.4e-14 51.2 0.4 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CEH16338.1 - 3.9e-19 69.0 0.0 9.7e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH16338.1 - 1.2e-09 38.4 0.0 4.1e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 CEH16338.1 - 4.2e-07 30.3 0.0 4.2e-07 30.3 0.0 4.0 3 0 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 DEAD PF00270.29 CEH16338.1 - 1.9e-05 24.5 0.0 3.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase CDH1_2_SANT_HL1 PF18375.1 CEH16338.1 - 0.039 14.6 0.0 0.039 14.6 0.0 3.2 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 LRR_9 PF14580.6 CEH16339.1 - 9.2e-57 191.3 0.1 1.1e-56 191.0 0.1 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CEH16339.1 - 9.1e-09 35.5 5.8 0.00086 19.7 0.1 2.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEH16339.1 - 2.2e-08 33.7 0.8 7.6e-08 32.0 0.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat cNMP_binding PF00027.29 CEH16340.1 - 4.6e-38 129.2 0.2 1.4e-17 63.5 0.1 3.1 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CEH16340.1 - 2.4e-11 43.1 0.8 4.5e-11 42.2 0.8 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit RPEL PF02755.15 CEH16341.1 - 1.9e-07 30.5 17.2 2.5e-05 23.8 2.1 3.8 4 1 0 4 4 4 2 RPEL repeat Pkinase PF00069.25 CEH16342.1 - 4.4e-29 101.7 0.0 1.6e-21 76.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH16342.1 - 3e-12 46.4 0.0 6.5e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH16342.1 - 0.00046 19.6 0.0 0.38 10.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DUF3704 PF12488.8 CEH16342.1 - 0.75 9.5 3.3 0.83 9.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) ADH_zinc_N PF00107.26 CEH16343.1 - 4.9e-31 107.4 0.1 1.1e-30 106.3 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEH16343.1 - 2e-12 48.3 0.0 3.3e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CEH16343.1 - 7e-05 22.2 0.3 0.00012 21.5 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 CEH16343.1 - 0.00043 20.1 0.0 0.002 18.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 CEH16343.1 - 0.013 15.0 0.6 0.027 13.9 0.2 1.8 2 0 0 2 2 2 0 short chain dehydrogenase HupF_HypC PF01455.18 CEH16343.1 - 0.014 15.6 0.1 0.051 13.7 0.0 2.1 2 0 0 2 2 2 0 HupF/HypC family Med14 PF08638.11 CEH16344.1 - 1.4e-50 171.4 0.0 2.5e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 CBP4 PF07960.11 CEH16345.1 - 4.1e-08 33.1 0.0 5.1e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 CEH16345.1 - 0.063 13.2 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 ADH_N PF08240.12 CEH16346.1 - 1.6e-30 105.2 0.3 3.9e-30 103.9 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEH16346.1 - 6.3e-21 74.7 0.0 1.1e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CEH16346.1 - 1.5e-05 24.4 0.1 3.5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 CEH16346.1 - 5.8e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 CEH16346.1 - 0.0011 19.2 0.1 0.0027 17.9 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Rhodanese PF00581.20 CEH16346.1 - 0.0069 16.9 0.0 0.027 15.0 0.0 2.1 3 0 0 3 3 3 1 Rhodanese-like domain ADH_zinc_N_2 PF13602.6 CEH16346.1 - 0.012 16.6 0.0 0.025 15.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 CEH16346.1 - 0.039 14.2 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_25 PF13649.6 CEH16346.1 - 0.12 13.1 0.0 0.4 11.4 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 CEH16346.1 - 0.18 11.2 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dmrt1 PF12374.8 CEH16346.1 - 7.8 7.0 7.2 3.6 8.1 0.1 3.0 3 0 0 3 3 2 0 Double-sex mab3 related transcription factor 1 Alpha-amylase PF00128.24 CEH16347.1 - 6.8e-97 325.0 0.0 9.5e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 CEH16347.1 - 0.096 11.8 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain BRE1 PF08647.11 CEH16348.1 - 5.3e-22 77.7 9.4 5.3e-22 77.7 9.4 6.3 5 1 1 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 CEH16348.1 - 7.7e-08 32.1 9.0 1.3e-07 31.3 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEH16348.1 - 5.4e-07 29.5 5.0 9.7e-07 28.7 5.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEH16348.1 - 3.7e-06 26.7 9.6 6.2e-06 26.0 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH16348.1 - 8e-06 25.7 11.2 1.3e-05 25.0 11.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CEH16348.1 - 1e-05 25.3 11.6 1.7e-05 24.6 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CEH16348.1 - 0.00032 20.5 2.6 0.00059 19.7 2.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 CEH16348.1 - 0.00056 20.2 9.7 0.00093 19.5 9.7 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CEH16348.1 - 0.00094 19.0 7.7 0.0017 18.2 7.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CEH16348.1 - 0.037 14.2 7.7 0.078 13.1 7.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CEH16348.1 - 0.045 14.1 4.9 0.094 13.0 4.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 CEH16348.1 - 1.7 8.6 5.6 3.2 7.7 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 CEH16348.1 - 4.4 6.9 4.4 2.2 7.8 1.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.6 CEH16348.1 - 4.5 7.1 9.4 14 5.6 9.4 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Gtr1_RagA PF04670.12 CEH16349.1 - 1.3e-85 286.5 0.0 1.7e-85 286.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 CEH16349.1 - 3.7e-06 27.1 0.0 8.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CEH16349.1 - 9.6e-06 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CEH16349.1 - 0.00012 21.5 0.0 0.00026 20.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CEH16349.1 - 0.00015 21.4 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CEH16349.1 - 0.013 14.7 0.5 3.3 6.8 0.0 2.4 1 1 1 2 2 2 0 G-protein alpha subunit Integrase_DNA PF02920.15 CEH16349.1 - 0.038 13.7 0.1 0.08 12.7 0.1 1.5 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase PduV-EutP PF10662.9 CEH16349.1 - 0.06 13.1 0.4 0.15 11.8 0.2 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DASH_Spc19 PF08287.11 CEH16349.1 - 0.069 13.1 0.1 0.26 11.2 0.0 2.0 2 1 0 2 2 2 0 Spc19 ABC_tran PF00005.27 CEH16349.1 - 0.15 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 CEH16349.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain X PF00739.19 CEH16351.1 - 0.045 13.9 0.3 0.049 13.8 0.3 1.1 1 0 0 1 1 1 0 Trans-activation protein X G-alpha PF00503.20 CEH16352.1 - 5.8e-122 407.3 2.6 6.6e-122 407.1 2.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEH16352.1 - 5.9e-17 61.7 2.2 6e-12 45.4 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEH16352.1 - 1.3e-05 24.7 3.7 0.00051 19.5 0.2 2.7 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region zf-CHC2 PF01807.20 CEH16352.1 - 9.4e-05 22.2 0.1 0.00034 20.4 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Roc PF08477.13 CEH16352.1 - 0.00053 20.2 0.2 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CEH16352.1 - 0.015 15.4 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CEH16352.1 - 0.017 14.8 0.6 0.076 12.8 0.2 2.2 2 1 1 3 3 3 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CEH16352.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 CEH16352.1 - 0.08 12.5 0.0 3.1 7.3 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain YgbB PF02542.16 CEH16352.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 YgbB family Carn_acyltransf PF00755.20 CEH16354.1 - 2.3e-205 683.7 0.0 2.7e-205 683.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Peptidase_M14 PF00246.24 CEH16355.1 - 2.9e-61 207.8 0.0 4.3e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Retrotrans_gag PF03732.17 CEH16357.1 - 3.9e-05 23.8 0.1 3.9e-05 23.8 0.1 2.0 2 1 0 2 2 2 1 Retrotransposon gag protein DcrB PF08786.11 CEH16357.1 - 0.061 13.4 3.4 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 DcrB DUF4554 PF15091.6 CEH16357.1 - 0.13 11.1 2.0 0.17 10.8 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) TBCC_N PF16752.5 CEH16357.1 - 0.21 12.0 9.4 0.19 12.2 8.0 1.7 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF4094 PF13334.6 CEH16357.1 - 1.6 9.2 4.9 1.3 9.5 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) ABC_tran_Xtn PF12848.7 CEH16357.1 - 1.9 8.6 10.3 5.2 7.2 10.3 1.8 1 0 0 1 1 1 0 ABC transporter TipAS PF07739.13 CEH16357.1 - 2.5 8.7 7.6 2.6 8.6 5.7 2.2 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain DUF349 PF03993.12 CEH16357.1 - 3.8 7.9 10.5 0.63 10.4 6.7 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) RT_RNaseH_2 PF17919.1 CEH16358.1 - 2.5e-36 123.7 0.0 5.3e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEH16358.1 - 1.1e-35 122.1 0.1 3e-35 120.7 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEH16358.1 - 1.7e-20 72.9 0.0 4.3e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CEH16358.1 - 4.8e-18 65.5 0.4 2.2e-17 63.3 0.4 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEH16358.1 - 2.4e-15 56.8 0.1 6.9e-15 55.3 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEH16358.1 - 4.1e-14 52.2 0.4 8.3e-14 51.2 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 CEH16358.1 - 4.4e-07 29.7 0.5 9.1e-07 28.7 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CEH16358.1 - 0.00081 19.1 1.1 0.0025 17.5 1.1 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 CEH16358.1 - 0.0027 17.5 2.0 0.0062 16.3 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 CEH16358.1 - 0.17 12.5 0.0 0.79 10.4 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease RVT_2 PF07727.14 CEH16360.1 - 6.9e-57 192.9 0.0 9.8e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CEH16360.1 - 2.5e-16 59.6 0.4 7e-16 58.1 0.2 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type rve PF00665.26 CEH16360.1 - 5.2e-16 58.9 0.0 2.1e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 CEH16360.1 - 7e-07 29.0 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CEH16360.1 - 0.0052 16.5 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 CEH16360.1 - 0.3 11.3 3.7 0.78 9.9 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 CEH16361.1 - 1.1e-72 244.6 0.0 1.4e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH16361.1 - 5.6e-30 104.5 0.0 1.7e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEH16361.1 - 6.2e-09 35.6 0.1 0.016 14.6 0.0 3.0 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 CEH16361.1 - 0.0028 16.5 0.0 0.0053 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEH16361.1 - 0.045 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH16361.1 - 0.11 12.4 0.1 0.55 10.1 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Abhydrolase_3 PF07859.13 CEH16363.1 - 3.2e-32 112.1 0.1 1.1e-22 81.0 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_31 PF13847.6 CEH16364.1 - 4.5e-13 49.3 0.0 7.2e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH16364.1 - 1.4e-11 45.0 0.2 3.2e-11 43.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 CEH16364.1 - 4e-11 42.8 0.1 5.7e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CEH16364.1 - 6.3e-10 39.1 0.0 3e-09 36.9 0.0 1.9 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH16364.1 - 2.1e-08 34.7 0.0 5.6e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEH16364.1 - 3.6e-07 29.8 0.0 4.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CEH16364.1 - 1.7e-06 28.7 0.0 3.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CEH16364.1 - 2.2e-05 23.6 0.0 3.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 CEH16364.1 - 4.4e-05 23.3 0.1 6.9e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CEH16364.1 - 9.3e-05 22.0 0.3 0.0002 20.9 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CEH16364.1 - 0.00058 19.8 0.1 0.0009 19.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CEH16364.1 - 0.00079 20.4 0.0 0.0016 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CEH16364.1 - 0.00098 19.3 0.4 0.0023 18.0 0.4 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 CEH16364.1 - 0.0012 18.2 0.1 0.0018 17.6 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 CEH16364.1 - 0.0069 16.1 0.2 0.01 15.6 0.2 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 CEH16364.1 - 0.023 14.3 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 CEH16364.1 - 0.026 14.5 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 CEH16364.1 - 0.36 10.2 1.5 0.59 9.5 0.3 2.0 2 1 0 2 2 2 0 Tellurite resistance protein TehB Tctex-1 PF03645.13 CEH16365.1 - 0.0038 17.4 0.5 0.068 13.4 0.5 2.2 1 1 0 1 1 1 1 Tctex-1 family DUF1577 PF07614.11 CEH16365.1 - 0.052 12.6 0.2 0.065 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) CarD_CdnL_TRCF PF02559.16 CEH16365.1 - 0.21 12.3 0.9 1.5 9.6 0.2 2.1 2 0 0 2 2 2 0 CarD-like/TRCF domain Methyltransf_16 PF10294.9 CEH16366.1 - 2e-39 135.1 0.0 2.5e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CEH16366.1 - 0.0026 17.3 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CEH16366.1 - 0.047 14.4 0.0 0.082 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GPI-anchored PF10342.9 CEH16367.1 - 0.00091 19.9 0.2 0.00091 19.9 0.2 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Apt1 PF10351.9 CEH16367.1 - 0.049 12.5 8.3 0.052 12.4 8.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMEM154 PF15102.6 CEH16367.1 - 0.11 12.5 1.7 0.19 11.6 1.7 1.4 1 0 0 1 1 1 0 TMEM154 protein family Inositol_P PF00459.25 CEH16367.1 - 0.15 11.5 0.5 0.22 11.0 0.5 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family SPX PF03105.19 CEH16367.1 - 0.3 11.0 11.5 0.31 10.9 11.5 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 CEH16367.1 - 0.9 8.7 13.6 1 8.5 13.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FAM220 PF15487.6 CEH16367.1 - 3.3 7.3 8.7 4.3 6.9 8.7 1.1 1 0 0 1 1 1 0 FAM220 family Tmemb_cc2 PF10267.9 CEH16367.1 - 9.4 5.3 6.2 11 5.0 6.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein EFP_N PF08207.12 CEH16368.1 - 0.13 12.3 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Aminotran_1_2 PF00155.21 CEH16370.1 - 3.6e-57 194.2 0.0 1.1e-56 192.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CEH16370.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2240 PF09999.9 CEH16370.1 - 0.13 11.9 0.0 1.9 8.1 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2240) Cys_Met_Meta_PP PF01053.20 CEH16370.1 - 0.22 10.0 0.0 1.4 7.4 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 CEH16371.1 - 2.5e-05 23.8 0.0 5.6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 CEH16371.1 - 2.9e-05 24.0 0.4 1.6 9.2 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 CEH16371.1 - 0.00022 21.3 0.0 0.0092 16.0 0.0 2.2 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 CEH16371.1 - 0.0032 16.8 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CEH16371.1 - 0.0081 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CLASP_N PF12348.8 CEH16371.1 - 0.018 14.6 0.0 0.16 11.5 0.0 2.1 1 1 1 2 2 2 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 CEH16371.1 - 0.16 12.6 0.0 9.5 6.9 0.0 2.6 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CEH16371.1 - 4.9 7.8 10.3 0.45 11.1 0.2 3.9 5 0 0 5 5 5 0 HEAT-like repeat UPF0113_N PF17833.1 CEH16372.1 - 1.5e-29 102.4 0.0 2.5e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CEH16372.1 - 2.1e-22 79.1 0.0 3.2e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 CEH16372.1 - 0.032 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain DUF1825 PF08855.10 CEH16372.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Pribosyltran_N PF13793.6 CEH16373.1 - 1.2e-41 141.3 0.2 2.9e-41 140.0 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CEH16373.1 - 4.6e-37 127.8 0.8 8.6e-31 107.4 0.3 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CEH16373.1 - 5.8e-15 55.2 1.9 7.8e-08 32.0 0.2 2.9 3 0 0 3 3 3 2 Phosphoribosyl transferase domain UPRTase PF14681.6 CEH16373.1 - 0.0032 16.9 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BRO1 PF03097.18 CEH16374.1 - 8.8e-18 64.3 0.0 4.8e-17 61.8 0.0 2.0 1 1 0 1 1 1 1 BRO1-like domain RNA_pol_Rpb1_R PF05001.13 CEH16374.1 - 0.92 10.0 5.5 2.6 8.6 5.5 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat IMS PF00817.20 CEH16375.1 - 1.4e-42 145.2 0.1 3.1e-42 144.1 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CEH16375.1 - 6.5e-12 46.2 0.9 3.8e-11 43.7 0.9 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CEH16375.1 - 1.1e-06 28.6 0.0 2.5e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif VPS28 PF03997.12 CEH16375.1 - 0.017 14.8 0.2 0.09 12.4 0.0 2.2 2 0 0 2 2 2 0 VPS28 protein UIM PF02809.20 CEH16375.1 - 6.1 7.0 10.4 0.29 11.1 3.5 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif tRNA-synt_2b PF00587.25 CEH16376.1 - 3.6e-38 131.3 0.0 9.6e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEH16376.1 - 1e-06 28.8 0.0 2.7e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.6 CEH16376.1 - 0.016 14.5 0.0 0.047 13.0 0.0 1.8 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Syntaxin-18_N PF10496.9 CEH16377.1 - 1.9e-09 37.6 0.3 2.4e-08 34.1 0.0 2.6 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 CEH16377.1 - 3.6e-05 23.7 0.1 0.00015 21.7 0.0 2.1 2 0 0 2 2 2 1 SNARE domain DUF2203 PF09969.9 CEH16377.1 - 0.35 11.6 4.5 0.98 10.2 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) RNase_PH PF01138.21 CEH16378.1 - 1e-25 90.7 0.2 1.6e-25 90.1 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNA_pol_Rpc34 PF05158.12 CEH16379.1 - 1.5e-73 248.1 0.1 3.3e-62 210.8 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit MarR PF01047.22 CEH16379.1 - 0.003 17.5 0.1 0.007 16.3 0.1 1.6 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 CEH16379.1 - 0.0092 15.8 0.1 3.6 7.6 0.1 2.7 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB HxlR PF01638.17 CEH16379.1 - 0.032 14.1 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix LT-IIB PF06453.11 CEH16379.1 - 0.09 12.7 0.0 0.88 9.5 0.0 2.1 2 0 0 2 2 2 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) F-box-like PF12937.7 CEH16381.1 - 9.1e-05 22.3 0.0 0.00033 20.5 0.0 2.0 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CEH16381.1 - 0.19 12.2 2.3 9 6.9 0.1 3.6 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) Sec1 PF00995.23 CEH16382.1 - 3.7e-107 360.0 0.0 4.3e-107 359.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family IU_nuc_hydro PF01156.19 CEH16383.1 - 7e-48 163.8 0.0 1.1e-47 163.1 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LEA_2 PF03168.13 CEH16385.1 - 6e-05 23.5 0.1 0.00016 22.1 0.0 1.9 2 0 0 2 2 2 1 Late embryogenesis abundant protein Arrestin_C PF02752.22 CEH16385.1 - 0.017 15.6 0.0 0.036 14.5 0.0 1.5 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Sigma54_DBD PF04552.13 CEH16385.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54, DNA binding domain VPS28 PF03997.12 CEH16386.1 - 4.5e-60 202.6 0.0 5.3e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein FAD_binding_1 PF00667.20 CEH16387.1 - 2e-56 191.0 0.0 3.2e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CEH16387.1 - 5.8e-33 114.1 0.8 1.1e-32 113.2 0.3 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CEH16387.1 - 9.1e-23 81.0 0.0 3.7e-22 79.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 CEH16387.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain PGF-CTERM PF18204.1 CEH16387.1 - 0.28 11.2 3.0 0.67 10.0 3.0 1.7 1 0 0 1 1 1 0 PGF-CTERM motif Glyco_H_20C_C PF18088.1 CEH16388.1 - 2.6e-39 135.1 0.0 6.4e-39 133.8 0.0 1.7 2 0 0 2 2 2 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 CEH16388.1 - 5.2e-12 45.8 0.0 2e-10 40.6 0.0 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHAD PF05235.14 CEH16388.1 - 0.038 14.0 0.2 1.5 8.8 0.0 2.5 2 1 0 2 2 2 0 CHAD domain Fungal_trans PF04082.18 CEH16389.1 - 7e-29 100.7 0.0 1.5e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain APG9 PF04109.16 CEH16389.1 - 0.048 12.7 0.1 0.07 12.1 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg9 SIR2 PF02146.17 CEH16390.1 - 1.5e-54 184.6 0.0 2.5e-54 183.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 CEH16390.1 - 2e-06 27.7 0.7 0.00078 19.2 0.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 CEH16390.1 - 0.023 14.4 0.1 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TRAPP PF04051.16 CEH16391.1 - 1.1e-19 70.7 0.1 7.4e-13 48.5 0.0 2.3 1 1 1 2 2 2 2 Transport protein particle (TRAPP) component FtsK_gamma PF09397.10 CEH16391.1 - 0.02 14.7 0.1 3.3 7.6 0.0 2.9 2 0 0 2 2 2 0 Ftsk gamma domain eIF-6 PF01912.18 CEH16392.1 - 8.4e-81 270.1 0.4 1.1e-80 269.6 0.4 1.2 1 0 0 1 1 1 1 eIF-6 family Hydrolase_4 PF12146.8 CEH16393.1 - 9.2e-48 162.6 0.0 1.8e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEH16393.1 - 1.3e-11 45.5 0.1 1.3e-11 45.5 0.1 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEH16393.1 - 4.6e-10 39.6 0.0 5e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Glyco_transf_8 PF01501.20 CEH16393.1 - 5.4e-08 32.7 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Peptidase_S9 PF00326.21 CEH16393.1 - 0.00015 21.3 0.1 0.0009 18.8 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 CEH16393.1 - 0.0026 17.4 0.0 0.0068 16.1 0.0 1.7 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 CEH16393.1 - 0.032 14.1 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_transf_24 PF18404.1 CEH16393.1 - 0.036 13.5 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Glucosyltransferase 24 DLH PF01738.18 CEH16393.1 - 0.048 13.2 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family LCAT PF02450.15 CEH16393.1 - 0.052 12.7 0.0 0.47 9.6 0.0 2.0 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.16 CEH16393.1 - 0.054 13.3 0.1 1.4 8.6 0.0 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 CEH16393.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Mannosyl_trans3 PF11051.8 CEH16393.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative RRM_1 PF00076.22 CEH16394.1 - 6.8e-58 192.4 0.0 3e-18 65.4 0.0 7.8 8 0 0 8 8 8 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRN3 PF05327.11 CEH16394.1 - 0.00016 20.4 1.3 0.00016 20.4 1.3 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 RRM_7 PF16367.5 CEH16394.1 - 0.00038 20.5 0.0 3 8.0 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 CEH16394.1 - 0.015 15.6 0.3 61 3.8 0.1 5.1 3 2 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 CEH16394.1 - 0.033 14.0 0.0 3.6 7.4 0.0 2.8 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 CEH16394.1 - 0.046 13.7 0.0 2.5 8.2 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif AhpC-TSA PF00578.21 CEH16395.1 - 7.6e-29 100.2 0.0 1e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEH16395.1 - 8.9e-12 44.9 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CEH16395.1 - 1.1e-08 34.7 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Herpes_V23 PF01802.17 CEH16395.1 - 0.037 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein DUF2375 PF09558.10 CEH16395.1 - 0.045 13.8 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) Latarcin PF10279.9 CEH16396.1 - 0.0034 17.8 1.3 0.0083 16.5 1.3 1.6 1 0 0 1 1 1 1 Latarcin precursor RHH_5 PF07878.11 CEH16396.1 - 0.023 14.6 0.3 0.083 12.8 0.3 2.0 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Cnd1 PF12717.7 CEH16396.1 - 0.088 12.8 0.0 25 4.9 0.0 2.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 MCM PF00493.23 CEH16397.1 - 3.7e-102 340.2 0.5 5.4e-102 339.6 0.5 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEH16397.1 - 5.9e-39 132.8 0.1 1.1e-38 132.0 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 CEH16397.1 - 8.1e-29 100.0 0.1 1.6e-28 99.1 0.1 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 CEH16397.1 - 1.2e-26 93.0 3.1 4e-26 91.2 1.2 2.4 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CEH16397.1 - 3.8e-18 66.0 0.9 8.8e-18 64.8 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CEH16397.1 - 7.5e-08 32.0 0.0 1e-06 28.3 0.1 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEH16397.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEH16397.1 - 0.0035 17.1 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Succ_DH_flav_C PF02910.20 CEH16397.1 - 0.0043 17.0 0.1 0.014 15.3 0.1 1.8 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term AAA_5 PF07728.14 CEH16397.1 - 0.024 14.6 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) His_Phos_2 PF00328.22 CEH16398.1 - 2.7e-70 237.7 0.0 3.7e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CEH16398.1 - 2.4e-32 110.9 0.0 5.4e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CEH16398.1 - 4.4e-06 26.4 0.0 8.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Proteasome PF00227.26 CEH16399.1 - 2.1e-24 86.1 0.0 2.5e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit TRP PF06011.12 CEH16400.1 - 9.3e-66 222.3 4.8 1.5e-65 221.6 4.8 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CEH16400.1 - 3e-31 108.7 0.1 4.4e-31 108.1 0.1 1.3 1 0 0 1 1 1 1 ML-like domain UPF0242 PF06785.11 CEH16400.1 - 1 9.5 1.7 1.3 9.1 0.4 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Corona_M PF01635.18 CEH16400.1 - 6.3 6.0 11.5 0.59 9.4 5.2 2.3 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein Erg28 PF03694.13 CEH16401.1 - 0.088 13.2 0.7 0.15 12.5 0.7 1.3 1 0 0 1 1 1 0 Erg28 like protein CSN8_PSD8_EIF3K PF10075.9 CEH16402.1 - 6.2e-31 107.3 0.0 8.1e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CEH16402.1 - 2.5e-05 23.8 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Proteasome PF00227.26 CEH16403.1 - 5.5e-59 198.8 0.1 9.2e-59 198.1 0.1 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 CEH16403.1 - 8.1e-13 47.8 0.2 1.4e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FtsZ_C PF12327.8 CEH16403.1 - 0.064 13.6 0.5 0.15 12.3 0.5 1.6 1 0 0 1 1 1 0 FtsZ family, C-terminal domain Asp PF00026.23 CEH16404.1 - 1.4e-41 143.0 0.0 2e-28 99.8 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEH16404.1 - 1.8e-12 47.8 2.6 1e-05 25.8 0.3 2.4 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal SbcCD_C PF13558.6 CEH16404.1 - 0.57 10.5 2.2 3.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CEH16406.1 - 1.1e-26 93.9 0.5 1.6e-26 93.4 0.1 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEH16406.1 - 0.00014 22.0 0.0 0.012 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CEH16406.1 - 0.00085 19.6 0.1 0.0035 17.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 CEH16406.1 - 0.0021 17.5 0.0 0.0048 16.4 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 CEH16406.1 - 0.0025 18.1 0.1 0.0099 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CEH16406.1 - 0.0026 17.2 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CEH16406.1 - 0.0034 17.8 0.1 0.0059 17.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.17 CEH16406.1 - 0.005 16.5 0.1 0.84 9.3 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase NTPase_1 PF03266.15 CEH16406.1 - 0.015 15.2 0.5 0.051 13.5 0.0 2.0 2 0 0 2 2 2 0 NTPase DAP3 PF10236.9 CEH16406.1 - 0.021 14.0 0.1 0.077 12.2 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 dNK PF01712.19 CEH16406.1 - 0.044 13.6 0.5 9.5 6.0 0.0 2.3 2 1 0 2 2 2 0 Deoxynucleoside kinase MeaB PF03308.16 CEH16406.1 - 0.047 12.7 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 CEH16406.1 - 0.05 13.6 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CEH16406.1 - 0.05 13.3 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEH16406.1 - 0.051 14.0 0.0 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 CEH16406.1 - 0.074 13.5 0.0 0.18 12.2 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CEH16406.1 - 0.083 12.5 0.3 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 CEH16406.1 - 0.087 12.9 0.0 0.53 10.4 0.1 2.0 2 0 0 2 2 2 0 Shikimate kinase ADK PF00406.22 CEH16406.1 - 0.09 12.9 0.1 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase AAA_17 PF13207.6 CEH16406.1 - 0.095 13.1 0.0 2.2 8.7 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 CEH16406.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain Put_Phosphatase PF06888.12 CEH16407.1 - 7e-49 166.3 0.0 8e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 CEH16407.1 - 7.6e-06 26.4 0.1 1.5e-05 25.5 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AP_endonuc_2 PF01261.24 CEH16408.1 - 2.4e-26 92.5 0.4 9.2e-26 90.6 0.1 2.0 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Vwaint PF14624.6 CEH16411.1 - 0.031 14.4 0.7 0.071 13.2 0.7 1.6 1 0 0 1 1 1 0 VWA / Hh protein intein-like Ras PF00071.22 CEH16412.1 - 8.3e-45 152.3 0.0 3.3e-42 143.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CEH16412.1 - 3.2e-33 114.5 0.1 4.8e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH16412.1 - 5.3e-12 45.5 0.0 9.2e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEH16412.1 - 1.4e-05 25.1 0.0 3.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CEH16412.1 - 0.00037 20.0 0.1 0.00059 19.3 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEH16412.1 - 0.0011 18.4 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 CEH16412.1 - 0.0058 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RhoGEF PF00621.20 CEH16413.1 - 9e-19 68.4 0.0 1.4e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain RNase_H PF00075.24 CEH16414.1 - 3.8e-32 111.4 0.0 1.1e-31 109.9 0.0 1.8 1 1 0 1 1 1 1 RNase H Cauli_VI PF01693.16 CEH16414.1 - 3e-17 62.6 0.9 6.8e-17 61.5 0.9 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 CEH16414.1 - 0.00062 19.6 0.7 0.0029 17.4 0.0 2.2 3 0 0 3 3 3 1 Reverse transcriptase-like DUF2797 PF10977.8 CEH16415.1 - 0.15 11.9 0.3 0.24 11.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) TRP PF06011.12 CEH16416.1 - 0.75 8.4 6.2 8.4 5.0 0.0 3.1 3 0 0 3 3 3 0 Transient receptor potential (TRP) ion channel Actin PF00022.19 CEH16417.1 - 4.6e-37 127.6 0.0 4.9e-36 124.2 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CEH16417.1 - 0.012 14.4 0.0 0.05 12.4 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein UPF0242 PF06785.11 CEH16420.1 - 0.0036 17.4 2.6 0.0036 17.4 2.6 5.5 1 1 2 3 3 3 2 Uncharacterised protein family (UPF0242) N-terminus CDPS PF16715.5 CEH16421.1 - 0.0086 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Cyclodipeptide synthase Utp14 PF04615.13 CEH16422.1 - 3.3e-35 121.9 0.9 4.2e-35 121.6 0.9 1.0 1 0 0 1 1 1 1 Utp14 protein Utp14 PF04615.13 CEH16423.1 - 2.4e-98 330.6 34.0 2.9e-70 237.8 6.9 2.0 1 1 1 2 2 2 2 Utp14 protein Ribonuc_red_lgC PF02867.15 CEH16424.1 - 2.1e-183 610.6 0.0 2.7e-183 610.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CEH16424.1 - 8.6e-25 86.6 0.0 2.1e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CEH16424.1 - 7.7e-17 61.7 0.1 1.9e-16 60.4 0.1 1.7 1 0 0 1 1 1 1 ATP cone domain GMC_oxred_N PF00732.19 CEH16425.1 - 9.1e-60 202.5 0.0 1.2e-59 202.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEH16425.1 - 6e-29 101.4 0.1 1.4e-28 100.2 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CEH16425.1 - 2.8e-05 23.4 1.4 0.00035 19.8 1.3 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CEH16425.1 - 0.00035 20.7 0.4 0.00097 19.3 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEH16425.1 - 0.0013 18.0 0.6 0.014 14.6 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEH16425.1 - 0.0015 17.8 1.1 0.25 10.6 1.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEH16425.1 - 0.0023 17.2 0.4 0.044 13.0 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 CEH16425.1 - 0.0032 16.6 0.3 0.0048 16.0 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CEH16425.1 - 0.0091 15.6 3.4 0.0091 15.6 3.4 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CEH16425.1 - 0.03 13.6 0.6 0.03 13.6 0.6 1.9 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 CEH16425.1 - 0.048 13.9 0.4 0.16 12.3 0.3 1.9 2 0 0 2 2 1 0 TrkA-N domain HI0933_like PF03486.14 CEH16425.1 - 0.058 12.1 0.5 0.1 11.3 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 CEH16425.1 - 0.1 13.2 0.8 0.23 12.0 0.8 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CEH16425.1 - 0.16 10.8 0.5 0.26 10.1 0.5 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Srg PF02118.21 CEH16426.1 - 0.065 12.9 0.4 0.1 12.2 0.4 1.2 1 0 0 1 1 1 0 Srg family chemoreceptor ketoacyl-synt PF00109.26 CEH16427.1 - 2.5e-58 197.6 2.0 3.4e-58 197.2 0.8 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CEH16427.1 - 1.7e-32 111.9 0.1 4.2e-32 110.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 CEH16427.1 - 1.2e-27 96.9 0.0 2.4e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 CEH16427.1 - 5.7e-24 85.2 0.3 9.3e-11 41.8 0.0 2.4 1 1 1 2 2 2 2 Acyl transferase domain KR PF08659.10 CEH16427.1 - 6.3e-12 45.8 0.0 1.5e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 CEH16427.1 - 1.2e-10 42.0 0.0 2.9e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 CEH16427.1 - 5.6e-10 39.4 0.0 1.5e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 CEH16427.1 - 4.8e-09 36.7 0.0 2.8e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 CEH16427.1 - 2.3e-08 34.0 0.0 5.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH16427.1 - 7.7e-06 25.8 0.0 2.3e-05 24.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain ACP_syn_III PF08545.10 CEH16427.1 - 9e-05 22.3 0.6 0.00043 20.1 0.6 2.3 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 CEH16427.1 - 0.0001 21.7 0.1 0.00024 20.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.6 CEH16427.1 - 0.00038 21.1 0.1 0.0034 18.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.12 CEH16427.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_11 PF08241.12 CEH16427.1 - 0.0059 17.2 0.1 0.025 15.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 CEH16427.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase MAGI_u5 PF16666.5 CEH16427.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI GMC_oxred_C PF05199.13 CEH16428.1 - 7.3e-28 97.9 0.0 1.8e-27 96.6 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CEH16428.1 - 1.6e-19 70.4 0.0 2.3e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase NmrA PF05368.13 CEH16429.1 - 2.4e-19 69.8 0.0 6.1e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 CEH16429.1 - 3.9e-15 56.2 0.1 1.1e-14 54.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CEH16429.1 - 0.00098 19.5 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 CEH16429.1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEH16429.1 - 0.0095 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_3 PF03447.16 CEH16429.1 - 0.032 14.9 0.1 0.83 10.3 0.1 2.8 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 CEH16429.1 - 0.047 12.9 0.1 0.19 10.9 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein AAA_21 PF13304.6 CEH16430.1 - 1.3e-06 28.5 0.8 1.3e-06 28.5 0.8 2.7 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CEH16430.1 - 2.4e-05 24.5 0.0 8.8e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF913 PF06025.12 CEH16431.1 - 0.11 11.5 0.9 0.14 11.1 0.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) LPD23 PF18838.1 CEH16432.1 - 0.039 13.7 0.7 0.061 13.1 0.1 1.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 Mit_KHE1 PF10173.9 CEH16433.1 - 1.8e-11 44.5 0.0 1.8e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related C2 PF00168.30 CEH16434.1 - 0.00011 22.5 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 CEH16435.1 - 2.2e-13 50.4 0.0 4.4e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 CEH16435.1 - 0.023 14.1 0.0 6.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain DUF966 PF06136.13 CEH16435.1 - 0.38 10.4 11.9 0.74 9.5 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Malic_M PF03949.15 CEH16436.1 - 5.9e-90 301.0 0.0 7.8e-90 300.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CEH16436.1 - 3.9e-65 219.1 0.0 7.1e-65 218.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain VWA PF00092.28 CEH16437.1 - 0.00025 21.3 0.0 0.00047 20.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Sdh_cyt PF01127.22 CEH16438.1 - 6.3e-23 81.1 1.3 7.8e-23 80.8 1.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NPL4 PF05021.15 CEH16439.1 - 2.3e-103 345.8 0.0 3.1e-103 345.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CEH16439.1 - 0.00038 20.6 0.0 0.00064 19.9 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region Mgm101p PF06420.12 CEH16439.1 - 0.055 13.0 0.1 0.088 12.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 zf-RanBP PF00641.18 CEH16439.1 - 0.11 11.9 1.2 0.22 10.9 1.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others FAD_binding_7 PF03441.14 CEH16440.1 - 1.7e-64 217.1 0.1 2.8e-64 216.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CEH16440.1 - 3.1e-32 111.8 0.0 5.3e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase HECT PF00632.25 CEH16441.1 - 5.3e-71 239.6 0.0 7.9e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 CEH16441.1 - 0.0034 17.0 1.3 0.0034 17.0 1.3 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif Ntox4 PF15541.6 CEH16443.1 - 0.093 13.1 0.1 0.17 12.3 0.1 1.4 1 1 1 2 2 2 0 Bacterial toxin 4 eIF3_N PF09440.10 CEH16444.1 - 4.6e-41 140.4 5.3 4.6e-41 140.4 5.3 2.1 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 CEH16444.1 - 6.7e-11 42.6 0.1 1.3e-10 41.7 0.1 1.5 1 0 0 1 1 1 1 PCI domain FoP_duplication PF13865.6 CEH16444.1 - 4.5 7.9 13.6 9.7 6.8 13.6 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Bmt2 PF11968.8 CEH16445.1 - 9.6e-29 100.8 0.8 2.2e-14 53.8 0.0 2.4 3 0 0 3 3 3 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 CEH16445.1 - 7.8e-05 22.6 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH16445.1 - 0.068 13.9 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 CEH16446.1 - 7.3e-16 58.3 0.0 2.5e-14 53.3 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH16446.1 - 6.8e-13 48.5 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEH16446.1 - 2.4e-05 24.4 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CEH16446.1 - 0.0024 17.5 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CEH16446.1 - 0.0098 14.9 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEH16446.1 - 0.051 12.9 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Homeodomain PF00046.29 CEH16448.1 - 6e-08 32.4 0.3 1.4e-07 31.3 0.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEH16448.1 - 2.8e-05 23.9 1.0 4.4e-05 23.3 0.2 1.8 2 0 0 2 2 2 1 Homeobox KN domain HTH_10 PF04967.12 CEH16449.1 - 0.018 14.8 0.1 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 HTH DNA binding domain DUF3952 PF13130.6 CEH16449.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) YabA PF06156.13 CEH16449.1 - 0.83 10.3 3.9 0.57 10.8 0.6 2.3 2 1 1 3 3 3 0 Initiation control protein YabA SHNi-TPR PF10516.9 CEH16453.1 - 2e-11 43.1 0.3 2e-11 43.1 0.3 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 CEH16453.1 - 0.0013 19.0 11.8 0.024 14.9 2.3 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF4533 PF15047.6 CEH16453.1 - 0.035 13.7 2.1 0.036 13.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) FIN1 PF17300.2 CEH16453.1 - 0.21 11.1 3.9 0.34 10.4 3.9 1.3 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Acyltransferase PF01553.21 CEH16455.1 - 5.4e-15 55.2 0.0 9.5e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase CTK3 PF12243.8 CEH16458.1 - 7.6e-20 71.2 0.0 5e-19 68.5 0.0 2.1 1 1 1 2 2 2 1 CTD kinase subunit gamma CTK3 RNA_pol_Rpb5_C PF01191.19 CEH16459.1 - 4.4e-32 109.8 0.2 9.2e-32 108.7 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CEH16459.1 - 8.1e-18 64.8 0.8 4.5e-17 62.4 0.1 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 CEH16459.1 - 0.0039 17.2 0.1 0.0081 16.2 0.1 1.6 1 1 1 2 2 2 1 Restriction endonuclease Peptidase_A3 PF02160.15 CEH16459.1 - 0.089 12.3 0.2 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) DUF4890 PF16231.5 CEH16459.1 - 0.41 11.2 2.6 1.1 9.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4890) p450 PF00067.22 CEH16460.1 - 1.2e-44 152.9 0.8 1.5e-17 63.5 0.2 3.0 1 1 2 3 3 3 3 Cytochrome P450 Armet PF10208.9 CEH16460.1 - 0.093 12.7 0.3 3.6 7.5 0.1 2.2 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding NUDIX PF00293.28 CEH16461.1 - 8.6e-12 45.2 0.1 1.5e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DUF1992 PF09350.10 CEH16462.1 - 3.8e-20 71.8 0.6 5.1e-19 68.2 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Solute_trans_a PF03619.16 CEH16464.1 - 4.2e-86 288.7 28.1 5.2e-86 288.4 28.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3605 PF12239.8 CEH16465.1 - 6.8e-21 75.2 0.1 9.6e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) DEAD PF00270.29 CEH16466.1 - 1.9e-29 102.7 0.0 3.1e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 CEH16466.1 - 9e-20 71.2 1.0 3.1e-19 69.5 1.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 CEH16466.1 - 3.1e-14 53.2 0.4 1.8e-13 50.8 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH16466.1 - 6.6e-05 23.0 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 CEH16466.1 - 0.0008 19.7 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like WW PF00397.26 CEH16467.1 - 1.3e-07 31.6 6.6 1.5e-07 31.4 5.4 1.8 2 0 0 2 2 2 1 WW domain eIF3m_C_helix PF18005.1 CEH16468.1 - 5.7e-09 35.5 0.8 1.2e-08 34.5 0.8 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 CEH16468.1 - 1.1e-08 35.6 0.0 5.6e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain BID PF06393.11 CEH16468.1 - 0.1 12.1 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) Ribosomal_L6e PF01159.19 CEH16469.1 - 5.3e-34 117.1 0.0 8.8e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e RNA_pol_I_A49 PF06870.12 CEH16470.1 - 3.2e-78 263.3 0.0 4.6e-78 262.8 0.0 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF2462 PF09495.10 CEH16471.1 - 9.1e-17 61.6 9.5 9.1e-17 61.6 9.5 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) DUF3224 PF11528.8 CEH16471.1 - 0.04 13.7 0.1 0.054 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) STE PF02200.16 CEH16474.1 - 2.5e-10 40.8 0.0 4.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor Nop25 PF09805.9 CEH16475.1 - 1.4e-18 67.6 18.0 1.4e-18 67.6 18.0 2.7 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) Ribosomal_S7 PF00177.21 CEH16476.1 - 1.9e-32 112.0 1.7 2.6e-32 111.5 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF4764 PF15961.5 CEH16477.1 - 0.028 13.1 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) Baseplate_J PF04865.14 CEH16477.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Baseplate J-like protein zf-C2H2_11 PF16622.5 CEH16477.1 - 0.18 11.6 1.2 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type Xpo1 PF08389.12 CEH16479.1 - 2.4e-16 60.2 0.0 1.2e-15 57.8 0.0 2.4 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 CEH16479.1 - 1.1 9.6 6.0 1.8 9.0 0.1 4.4 5 0 0 5 5 5 0 HEAT repeats HEAT PF02985.22 CEH16479.1 - 1.4 9.4 4.3 2.1 8.8 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat PIG-X PF08320.12 CEH16483.1 - 2.7e-07 30.7 0.0 0.00023 21.2 0.0 2.7 2 1 0 2 2 2 2 PIG-X / PBN1 ThiF PF00899.21 CEH16484.1 - 4.3e-16 59.0 0.0 1.5e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 ThiF family DHHC PF01529.20 CEH16485.1 - 1.4e-37 128.7 4.3 1.4e-37 128.7 4.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.7 CEH16485.1 - 0.77 9.8 7.8 1.4 9.0 7.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 CEH16485.1 - 1.9 8.3 4.3 3.7 7.4 4.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain ABC2_membrane PF01061.24 CEH16485.1 - 6.1 6.2 14.8 0.026 13.9 2.7 2.2 2 1 0 2 2 2 0 ABC-2 type transporter 2OG-FeII_Oxy_2 PF13532.6 CEH16487.1 - 2.8e-16 60.3 1.3 7.8e-14 52.3 0.0 3.1 2 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily GLE1 PF07817.13 CEH16489.1 - 2.5e-64 216.9 0.0 3.7e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein Elongin_A PF06881.11 CEH16490.1 - 2.8e-08 34.2 0.1 1.2e-07 32.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Amino_oxidase PF01593.24 CEH16492.1 - 3.9e-33 115.4 0.2 1.7e-15 57.3 0.0 3.1 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEH16492.1 - 1.9e-12 47.2 0.0 6.6e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CEH16492.1 - 0.014 14.1 0.1 0.02 13.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 CEH16492.1 - 0.16 11.2 0.0 1.1 8.5 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 CEH16493.1 - 1.7e-20 73.3 42.9 4.2e-14 52.3 29.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_Tnp_Tc5 PF03221.16 CEH16494.1 - 1.5e-09 37.7 0.1 3.8e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Crp_2 PF13545.6 CEH16494.1 - 0.0049 16.8 0.3 1.7 8.7 0.0 3.0 3 0 0 3 3 3 2 Crp-like helix-turn-helix domain CENP-B_N PF04218.13 CEH16494.1 - 0.033 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_4 PF13613.6 CEH16494.1 - 0.06 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease SPX PF03105.19 CEH16498.1 - 0.0051 16.8 3.5 0.0051 16.8 3.5 2.6 2 1 0 2 2 2 1 SPX domain Rhodanese PF00581.20 CEH16499.1 - 1.3e-14 54.6 0.0 1.9e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Fungal_trans PF04082.18 CEH16502.1 - 6.9e-09 35.1 0.0 7.3e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain MRP-S28 PF10213.9 CEH16503.1 - 1.7e-27 96.3 0.0 2.7e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein adh_short PF00106.25 CEH16504.1 - 6.1e-50 169.4 0.8 8.8e-50 168.9 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH16504.1 - 1.7e-30 106.3 1.2 2.3e-30 105.9 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH16504.1 - 1.6e-08 34.7 0.2 2.4e-08 34.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEH16504.1 - 5.1e-07 29.4 0.4 3e-06 26.9 0.2 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CEH16504.1 - 4.9e-06 26.6 0.7 1.2e-05 25.3 0.3 1.8 1 1 1 2 2 2 1 NAD(P)H-binding SurE PF01975.17 CEH16504.1 - 0.005 16.6 0.4 0.063 13.0 0.1 2.1 2 0 0 2 2 2 1 Survival protein SurE RmlD_sub_bind PF04321.17 CEH16504.1 - 0.021 13.9 0.1 0.048 12.8 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain CHDNT PF08073.12 CEH16504.1 - 0.056 13.4 0.6 0.36 10.8 0.6 2.1 1 1 0 1 1 1 0 CHDNT (NUC034) domain DUF5470 PF17564.2 CEH16504.1 - 0.068 13.4 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5470) 2-Hacid_dh_C PF02826.19 CEH16505.1 - 5.7e-58 195.2 0.0 8.1e-58 194.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEH16505.1 - 2.4e-16 59.6 0.0 3e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CEH16505.1 - 1e-07 32.2 0.0 3.7e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CEH16505.1 - 0.0045 16.6 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 CEH16505.1 - 0.0063 17.1 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 CEH16505.1 - 0.088 12.1 0.5 0.18 11.2 0.5 1.4 1 0 0 1 1 1 0 ThiF family Gln-synt_C-ter PF18318.1 CEH16505.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase C-terminal domain Ribosomal_L3 PF00297.22 CEH16506.1 - 4.8e-12 45.5 0.5 9.6e-12 44.6 0.6 1.4 2 0 0 2 2 2 1 Ribosomal protein L3 CMAS PF02353.20 CEH16507.1 - 5.5e-64 216.1 0.3 7e-64 215.8 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CEH16507.1 - 8.5e-15 55.2 0.2 2.9e-13 50.3 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH16507.1 - 2.8e-14 53.6 0.1 4.2e-12 46.6 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH16507.1 - 8.9e-12 45.2 0.0 2e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 CEH16507.1 - 2.1e-06 27.4 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 CEH16507.1 - 6.6e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CEH16507.1 - 3.1e-05 23.8 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 CEH16507.1 - 4.2e-05 24.2 0.0 0.00011 22.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEH16507.1 - 0.0003 20.4 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 CEH16507.1 - 0.0034 16.5 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 CEH16507.1 - 0.0094 16.0 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CEH16507.1 - 0.048 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF4672 PF15716.5 CEH16507.1 - 0.06 13.0 1.9 0.11 12.1 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) DUF21 PF01595.20 CEH16508.1 - 6.2e-36 123.7 0.2 1.8e-35 122.3 0.2 1.8 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CEH16508.1 - 3e-06 27.6 0.6 0.064 13.7 0.0 3.3 3 0 0 3 3 3 2 CBS domain Casc1_N PF15927.5 CEH16508.1 - 2.2 7.9 8.4 4.4 6.9 8.4 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF1681 PF07933.14 CEH16510.1 - 7.5e-52 175.0 0.0 8.8e-52 174.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) FA_hydroxylase PF04116.13 CEH16515.1 - 3.5e-23 82.4 7.6 3.5e-23 82.4 7.6 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 CEH16516.1 - 3.8e-27 95.1 44.3 1.6e-26 93.1 37.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SRAP PF02586.14 CEH16517.1 - 1e-42 146.2 0.0 1.7e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Asp-B-Hydro_N PF05279.11 CEH16517.1 - 0.016 15.3 17.6 0.024 14.7 17.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HD_3 PF13023.6 CEH16519.1 - 2.7e-42 144.5 0.1 2.7e-42 144.5 0.1 1.8 2 0 0 2 2 2 1 HD domain HD_2 PF12917.7 CEH16519.1 - 1.2e-09 38.1 0.2 2.3e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CEH16519.1 - 0.029 14.6 0.4 0.069 13.4 0.4 1.6 1 0 0 1 1 1 0 HD domain Acetyltransf_1 PF00583.25 CEH16520.1 - 1.5e-09 38.1 0.0 5e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEH16520.1 - 1.6e-07 31.6 0.1 2.6e-06 27.8 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEH16520.1 - 3.7e-06 26.9 0.3 0.012 15.6 0.1 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CEH16520.1 - 0.018 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEH16520.1 - 0.043 13.8 0.2 0.45 10.5 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein DUF3408 PF11888.8 CEH16520.1 - 0.054 13.6 0.4 0.076 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) KAAG1 PF15354.6 CEH16520.1 - 0.46 11.1 2.2 0.36 11.4 0.5 1.7 2 0 0 2 2 2 0 Kidney-associated antigen 1 Arf PF00025.21 CEH16521.1 - 1.4e-79 265.6 0.1 1.6e-79 265.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEH16521.1 - 1.5e-14 54.2 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CEH16521.1 - 2.6e-14 53.1 0.0 3.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CEH16521.1 - 4.7e-13 49.1 0.0 5.1e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CEH16521.1 - 6e-13 48.7 1.2 3.9e-09 36.1 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CEH16521.1 - 1.1e-10 41.3 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEH16521.1 - 2.3e-06 27.6 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CEH16521.1 - 0.0069 15.7 0.7 0.019 14.2 0.7 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase EPL1 PF10513.9 CEH16522.1 - 5.4e-19 69.1 0.0 5.4e-19 69.1 0.0 3.5 3 1 0 3 3 3 1 Enhancer of polycomb-like DUF2605 PF10792.9 CEH16522.1 - 0.066 13.1 2.3 0.53 10.2 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) GMC_oxred_N PF00732.19 CEH16525.1 - 2.3e-54 184.8 0.0 3.1e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEH16525.1 - 4.7e-36 124.5 0.0 7.6e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 CEH16525.1 - 4e-06 26.3 0.1 0.0013 18.0 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEH16525.1 - 0.00021 20.5 5.4 0.17 10.9 2.7 2.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CEH16525.1 - 0.001 19.3 0.9 0.0027 17.9 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CEH16525.1 - 0.0018 17.4 0.7 0.0027 16.8 0.7 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CEH16525.1 - 0.026 14.1 5.4 0.087 12.4 2.3 2.8 4 0 0 4 4 4 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CEH16525.1 - 0.21 10.2 0.6 0.46 9.1 0.6 1.5 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 CEH16525.1 - 0.22 11.8 0.2 0.47 10.7 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain EF_assoc_2 PF08356.12 CEH16526.1 - 6.7e-28 96.5 0.0 6.4e-27 93.4 0.0 2.2 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 CEH16526.1 - 1.4e-26 93.0 0.0 3.2e-17 62.6 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 CEH16526.1 - 1.7e-26 91.6 1.3 4.9e-26 90.1 0.2 2.3 2 0 0 2 2 2 1 EF hand associated Roc PF08477.13 CEH16526.1 - 2.6e-16 59.9 0.0 2e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 CEH16526.1 - 3.1e-10 39.2 0.2 0.00082 19.1 0.0 2.9 3 0 0 3 3 2 2 EF-hand domain EF-hand_7 PF13499.6 CEH16526.1 - 5e-09 36.5 0.1 0.0033 17.8 0.1 2.7 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CEH16526.1 - 1.5e-08 33.6 1.2 0.0067 15.9 0.1 2.9 3 0 0 3 3 3 2 EF hand MMR_HSR1 PF01926.23 CEH16526.1 - 1.3e-07 31.7 0.0 0.0078 16.3 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CEH16526.1 - 8.8e-06 26.0 0.0 0.2 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain EF-hand_5 PF13202.6 CEH16526.1 - 1.3e-05 24.4 4.1 0.0031 16.9 0.1 2.9 3 0 0 3 3 2 2 EF hand RsgA_GTPase PF03193.16 CEH16526.1 - 2.3e-05 24.3 0.1 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CEH16526.1 - 3.4e-05 24.3 0.2 0.3 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CEH16526.1 - 4.2e-05 23.2 0.2 0.41 10.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran PF00005.27 CEH16526.1 - 8.9e-05 23.0 0.1 0.32 11.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter Dynamin_N PF00350.23 CEH16526.1 - 0.00018 21.6 0.5 0.11 12.6 0.1 2.4 2 1 0 2 2 2 1 Dynamin family NACHT PF05729.12 CEH16526.1 - 0.00027 20.9 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 CEH16526.1 - 0.0003 20.6 0.2 0.45 10.2 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 CEH16526.1 - 0.00043 20.4 0.1 0.7 10.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CEH16526.1 - 0.00071 19.1 0.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 CEH16526.1 - 0.0013 18.5 0.1 0.92 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEH16526.1 - 0.0024 18.4 0.5 0.2 12.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CEH16526.1 - 0.0027 18.1 0.0 0.45 10.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.18 CEH16526.1 - 0.0031 16.9 0.1 0.056 12.8 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF815 PF05673.13 CEH16526.1 - 0.0034 16.6 0.1 2.5 7.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) MCM PF00493.23 CEH16526.1 - 0.0063 15.6 0.1 0.4 9.7 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain AAA_24 PF13479.6 CEH16526.1 - 0.008 15.9 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CEH16526.1 - 0.008 15.4 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain SPARC_Ca_bdg PF10591.9 CEH16526.1 - 0.0097 16.2 0.1 9.2 6.6 0.0 3.2 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Septin PF00735.18 CEH16526.1 - 0.012 14.9 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 CEH16526.1 - 0.013 15.1 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 CEH16526.1 - 0.014 14.5 0.3 0.79 8.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Arf PF00025.21 CEH16526.1 - 0.015 14.8 0.0 3.3 7.1 0.0 3.2 3 1 0 3 3 3 0 ADP-ribosylation factor family Ploopntkinase3 PF18751.1 CEH16526.1 - 0.016 15.1 0.0 6.3 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 EF-hand_8 PF13833.6 CEH16526.1 - 0.017 15.0 0.4 7 6.6 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair SRPRB PF09439.10 CEH16526.1 - 0.017 14.5 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 CEH16526.1 - 0.02 15.1 0.1 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 CEH16526.1 - 0.02 14.6 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E ATP_bind_1 PF03029.17 CEH16526.1 - 0.021 14.6 1.5 6.7 6.4 0.2 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 CEH16526.1 - 0.025 14.9 0.1 9.4 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CEH16526.1 - 0.027 14.0 0.2 7.1 6.2 0.0 2.6 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 CEH16526.1 - 0.028 13.7 0.0 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AIG1 PF04548.16 CEH16526.1 - 0.043 13.1 0.5 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 AIG1 family AAA PF00004.29 CEH16526.1 - 0.051 14.0 0.1 1.2 9.5 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 CEH16526.1 - 0.07 12.3 0.2 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit TsaE PF02367.17 CEH16526.1 - 0.1 12.6 0.0 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF-hand_10 PF14788.6 CEH16526.1 - 0.11 12.4 1.4 0.32 10.9 0.2 2.1 2 0 0 2 2 2 0 EF hand NTPase_1 PF03266.15 CEH16526.1 - 0.15 12.0 0.1 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 NTPase Adeno_IVa2 PF02456.15 CEH16526.1 - 0.21 10.3 0.1 5.2 5.7 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein TrwB_AAD_bind PF10412.9 CEH16526.1 - 0.26 10.1 0.0 13 4.6 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Aldedh PF00171.22 CEH16527.1 - 2.1e-125 418.9 1.2 2.6e-125 418.6 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 CEH16527.1 - 0.00032 19.9 0.1 0.00064 18.9 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pox_TAA1 PF03295.14 CEH16527.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal S4 PF01479.25 CEH16527.1 - 0.072 12.8 0.2 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 S4 domain eIF-5_eIF-2B PF01873.17 CEH16528.1 - 1.4e-40 137.8 0.1 2.1e-40 137.3 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 CEH16528.1 - 0.021 14.4 0.1 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-HYPF PF07503.12 CEH16528.1 - 0.063 13.1 0.4 9.2 6.1 0.1 2.5 2 0 0 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 CEH16528.1 - 0.18 12.2 3.8 2 8.8 0.0 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain DUF3275 PF11679.8 CEH16528.1 - 0.32 11.0 4.9 0.51 10.3 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Elf1 PF05129.13 CEH16528.1 - 2.2 8.4 5.6 0.2 11.7 0.7 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like CK_II_beta PF01214.18 CEH16529.1 - 9.5e-76 253.7 0.0 1.3e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Pho88 PF10032.9 CEH16531.1 - 1.9e-70 235.9 0.0 2.1e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DER1 PF04511.15 CEH16532.1 - 1.2e-49 168.9 3.6 1.4e-49 168.7 3.6 1.0 1 0 0 1 1 1 1 Der1-like family PRP3 PF08572.10 CEH16533.1 - 2.6e-69 233.4 0.3 2.6e-69 233.4 0.3 1.5 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CEH16533.1 - 2.6e-36 124.9 0.1 1.1e-35 122.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) U3_snoRNA_assoc PF08297.11 CEH16533.1 - 1.6 9.5 12.7 0.2 12.4 1.6 3.5 3 0 0 3 3 3 0 U3 snoRNA associated 3HCDH_N PF02737.18 CEH16534.1 - 3.4e-52 177.0 3.4 4.6e-52 176.5 3.4 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CEH16534.1 - 7.6e-07 29.7 0.1 3.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.14 CEH16534.1 - 0.00072 19.2 0.6 0.0018 17.9 0.6 1.7 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 CEH16534.1 - 0.003 17.8 1.6 0.0091 16.3 1.6 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF1188 PF06690.11 CEH16534.1 - 0.0091 15.6 0.1 0.019 14.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_Gly3P_dh_N PF01210.23 CEH16534.1 - 0.0096 15.9 1.1 0.018 15.0 1.1 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 CEH16534.1 - 0.014 15.5 5.4 0.35 11.0 4.6 2.7 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CEH16534.1 - 0.11 12.6 2.6 0.37 10.9 1.5 2.4 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CEH16534.1 - 0.48 11.0 5.3 23 5.7 5.3 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_N PF08240.12 CEH16535.1 - 1.2e-26 92.7 1.7 1.2e-26 92.7 1.7 2.4 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEH16535.1 - 1.1e-13 51.4 0.1 1.9e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CEH16535.1 - 9.2e-05 22.0 1.1 0.00045 19.8 1.1 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CEH16535.1 - 0.055 14.5 0.0 0.11 13.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Polysacc_deac_1 PF01522.21 CEH16537.1 - 8.5e-23 80.6 0.0 1.7e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEH16537.1 - 0.0044 16.3 0.0 0.011 15.0 0.0 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 DPBB_1 PF03330.18 CEH16538.1 - 6.4e-09 36.0 0.0 1.4e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase MGC-24 PF05283.11 CEH16538.1 - 0.022 15.2 11.4 0.046 14.2 11.4 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SOG2 PF10428.9 CEH16538.1 - 0.029 13.6 13.4 0.037 13.2 13.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Sporozoite_P67 PF05642.11 CEH16538.1 - 0.044 11.9 13.0 0.059 11.5 13.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 CEH16538.1 - 0.11 10.7 23.3 0.15 10.2 23.3 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DAG_kinase_N PF14513.6 CEH16538.1 - 0.23 11.6 3.5 0.37 11.0 3.5 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus SPX PF03105.19 CEH16538.1 - 0.44 10.4 8.3 0.61 9.9 8.3 1.3 1 0 0 1 1 1 0 SPX domain NPR3 PF03666.13 CEH16538.1 - 0.47 9.2 3.8 0.58 8.9 3.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 CEH16538.1 - 0.49 9.2 12.1 0.62 8.8 12.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ORC6 PF05460.13 CEH16538.1 - 0.62 9.3 9.7 0.69 9.1 9.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SpoIIIAH PF12685.7 CEH16538.1 - 4.1 7.2 9.8 6.4 6.5 9.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Presenilin PF01080.17 CEH16538.1 - 4.3 6.0 6.7 6 5.5 6.7 1.1 1 0 0 1 1 1 0 Presenilin Mucin PF01456.17 CEH16538.1 - 4.3 7.3 33.3 0.19 11.7 27.3 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Sec3_C PF09763.9 CEH16538.1 - 5.5 5.3 4.9 6.4 5.0 4.9 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 TPR_MLP1_2 PF07926.12 CEH16539.1 - 1.8e-26 92.7 24.7 1.8e-26 92.7 24.7 19.0 6 4 11 19 19 19 5 TPR/MLP1/MLP2-like protein DUF1492 PF07374.11 CEH16539.1 - 0.72 10.0 8.8 3.8 7.7 0.0 5.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1492) Jag_N PF14804.6 CEH16539.1 - 6 7.3 6.1 7.4 7.0 0.1 3.9 3 0 0 3 3 3 0 Jag N-terminus Na_H_Exchanger PF00999.21 CEH16540.1 - 3.8e-64 216.9 24.7 5.1e-64 216.4 24.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CAS_CSE1 PF03378.15 CEH16542.1 - 3.3e-126 421.4 0.0 8.7e-126 420.0 0.0 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 CEH16542.1 - 7e-117 390.4 0.0 1.3e-116 389.5 0.0 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 CEH16542.1 - 5.6e-09 35.8 0.1 1.7e-07 31.1 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CEH16542.1 - 0.00049 20.2 2.7 0.014 15.5 0.0 4.3 5 1 1 6 6 6 1 Exportin 1-like protein MOR2-PAG1_C PF14225.6 CEH16542.1 - 0.2 11.5 2.1 0.75 9.6 0.4 2.7 3 0 0 3 3 3 0 Cell morphogenesis C-terminal WD40 PF00400.32 CEH16543.1 - 3e-23 81.7 14.6 0.00011 22.9 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 CEH16543.1 - 0.064 11.9 0.8 1 7.9 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEH16543.1 - 0.18 10.7 0.0 8.8 5.2 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LMWPc PF01451.21 CEH16544.1 - 1.1e-37 129.6 0.0 1.3e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase LAT PF15234.6 CEH16546.1 - 0.14 11.8 0.6 0.17 11.6 0.6 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells RTC PF01137.21 CEH16547.1 - 1.7e-50 171.3 0.1 2e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CEH16547.1 - 1.6e-29 102.4 0.0 2.8e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF1752 PF08550.10 CEH16548.1 - 4.9e-11 42.3 1.5 9.1e-11 41.4 1.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3295 PF11702.8 CEH16548.1 - 9.9e-10 38.4 7.6 9.9e-10 38.4 7.6 6.1 3 2 1 6 6 6 1 Protein of unknown function (DUF3295) Enkurin PF13864.6 CEH16548.1 - 7.5 7.1 7.4 0.68 10.4 0.3 2.4 2 0 0 2 2 2 0 Calmodulin-binding SAP30_Sin3_bdg PF13867.6 CEH16550.1 - 0.0013 19.0 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 ANAPC4_WD40 PF12894.7 CEH16551.1 - 2.7e-07 30.8 0.2 0.0012 19.0 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEH16551.1 - 3e-05 24.7 2.0 0.33 11.9 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat TFIIIC_delta PF12657.7 CEH16551.1 - 0.00012 22.1 0.2 0.00055 19.9 0.0 2.2 2 1 1 3 3 3 1 Transcription factor IIIC subunit delta N-term Thiolase_N PF00108.23 CEH16552.1 - 3.4e-20 72.5 0.2 4.5e-18 65.6 0.0 2.5 2 1 1 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEH16552.1 - 1.9e-10 40.5 0.5 1.6e-09 37.5 0.4 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEH16552.1 - 7.1e-07 29.1 3.2 0.00021 21.0 1.2 2.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CEH16552.1 - 0.014 15.2 0.3 0.36 10.7 0.2 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 CEH16552.1 - 0.016 13.9 0.0 0.48 9.1 0.0 2.2 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 CEH16552.1 - 0.12 12.4 1.0 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain Pkinase PF00069.25 CEH16553.1 - 8.1e-37 127.0 0.0 2.7e-36 125.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH16553.1 - 4.6e-16 58.9 0.0 8.9e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEH16553.1 - 0.0027 17.1 0.0 0.013 14.8 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH16553.1 - 0.0087 16.0 0.1 0.0087 16.0 0.1 3.2 4 0 0 4 4 4 1 Phosphotransferase enzyme family NAD_binding_10 PF13460.6 CEH16555.1 - 1.8e-12 47.6 0.0 3.7e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CEH16555.1 - 3.9e-12 46.2 0.0 5.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CEH16555.1 - 4e-12 46.1 0.1 5.8e-11 42.3 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEH16555.1 - 1.3e-11 44.0 0.1 7.3e-11 41.6 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CEH16555.1 - 1.2e-09 37.7 0.0 2e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CEH16555.1 - 1e-05 24.8 0.1 0.044 12.9 0.1 3.1 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 CEH16555.1 - 0.00043 19.8 0.0 0.00076 19.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 CEH16555.1 - 0.00045 19.7 0.0 0.00095 18.7 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 CEH16555.1 - 0.0017 17.9 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH16555.1 - 0.0046 16.9 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 KR domain DapB_N PF01113.20 CEH16555.1 - 0.015 15.4 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 CEH16555.1 - 0.038 13.1 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HMGL-like PF00682.19 CEH16557.1 - 1.6e-26 93.4 0.0 7.2e-21 74.9 0.0 2.1 1 1 1 2 2 2 2 HMGL-like Thiolase_C PF02803.18 CEH16558.1 - 2.8e-44 149.7 0.3 4.6e-44 149.0 0.3 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 CEH16558.1 - 2.2e-36 125.6 1.4 1e-35 123.4 0.4 2.0 1 1 1 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III_C PF08541.10 CEH16558.1 - 0.0031 17.6 0.1 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal GPI-anchored PF10342.9 CEH16560.1 - 2.7e-10 40.9 1.0 3e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HRXXH PF13933.6 CEH16561.1 - 6.1e-73 245.4 0.0 7.9e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Zip PF02535.22 CEH16563.1 - 2.2e-40 138.9 16.0 2.2e-40 138.9 16.0 2.6 2 1 0 2 2 2 2 ZIP Zinc transporter SCP2 PF02036.17 CEH16564.1 - 0.019 15.5 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 SCP-2 sterol transfer family ANAPC4_WD40 PF12894.7 CEH16566.1 - 2e-06 28.0 0.0 0.25 11.7 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEH16566.1 - 9.1e-05 23.2 0.1 0.0024 18.7 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CEH16566.1 - 0.16 10.9 0.1 0.9 8.4 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein XPG_I PF00867.18 CEH16567.1 - 8.3e-11 42.1 0.2 5.8e-10 39.4 0.2 2.3 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CEH16567.1 - 8.6e-05 22.9 0.1 0.004 17.6 0.1 2.4 1 1 1 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 CEH16567.1 - 0.00062 19.3 0.1 0.00062 19.3 0.1 2.0 3 0 0 3 3 3 1 XPG domain containing HhH-GPD PF00730.25 CEH16568.1 - 1.9e-10 41.1 0.0 3.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UbiA PF01040.18 CEH16569.1 - 1e-55 188.8 21.4 1.5e-55 188.3 21.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Cullin PF00888.22 CEH16570.1 - 7.4e-183 609.5 7.1 7.4e-183 609.5 7.1 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CEH16570.1 - 4.3e-27 93.9 4.0 4.3e-27 93.9 4.0 2.4 3 0 0 3 3 3 1 Cullin protein neddylation domain DUF2848 PF11010.8 CEH16570.1 - 0.082 12.5 0.1 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) Penicillinase_R PF03965.16 CEH16570.1 - 0.25 11.7 0.1 0.25 11.7 0.1 3.6 4 1 0 4 4 4 0 Penicillinase repressor Arv1 PF04161.13 CEH16571.1 - 2.6e-34 119.2 0.1 3.4e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Arv1-like family HMGL-like PF00682.19 CEH16573.1 - 6.7e-75 252.1 0.0 9.7e-75 251.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 CEH16573.1 - 1.9e-16 60.2 0.1 3.5e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain MAPEG PF01124.18 CEH16574.1 - 8.6e-08 32.2 0.1 1.2e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 MAPEG family adh_short_C2 PF13561.6 CEH16575.1 - 1.1e-42 146.1 0.3 1.5e-42 145.7 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH16575.1 - 2.3e-36 125.1 0.1 3.1e-36 124.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH16575.1 - 7.1e-12 45.6 0.2 1e-11 45.1 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CEH16575.1 - 0.027 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) COesterase PF00135.28 CEH16580.1 - 3.7e-79 266.9 0.0 1.8e-77 261.4 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CEH16580.1 - 2.2e-06 27.7 0.1 6.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold SET PF00856.28 CEH16581.1 - 1.6e-12 48.1 0.0 2.9e-10 40.8 0.0 3.4 2 1 0 2 2 2 1 SET domain Glyco_transf_15 PF01793.16 CEH16582.1 - 5.5e-94 315.1 0.0 7e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ldh_1_N PF00056.23 CEH16586.1 - 1.5e-43 148.3 0.0 2.2e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CEH16586.1 - 3.9e-37 127.8 0.0 3.8e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CEH16586.1 - 0.002 17.2 0.0 0.0042 16.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 CEH16586.1 - 0.015 14.6 0.0 0.064 12.6 0.0 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 CEH16586.1 - 0.029 14.8 0.1 0.076 13.5 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 CEH16586.1 - 0.12 11.9 0.1 0.35 10.4 0.1 1.7 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase DUF3292 PF11696.8 CEH16587.1 - 3.3e-11 42.3 25.2 1.1e-05 24.1 1.3 4.5 5 0 0 5 5 5 3 Protein of unknown function (DUF3292) PRT_C PF08372.10 CEH16587.1 - 3.3e-06 26.9 0.7 6.5e-06 26.0 0.7 1.4 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 CEH16587.1 - 0.00013 22.0 5.1 0.018 15.0 2.4 2.3 2 0 0 2 2 2 2 Reticulon Pex24p PF06398.11 CEH16587.1 - 0.11 11.5 0.1 0.59 9.0 0.0 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Sin_N PF04801.13 CEH16587.1 - 0.21 10.8 3.5 0.37 10.0 3.5 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region EI24 PF07264.11 CEH16587.1 - 0.49 10.6 6.2 0.8 9.9 6.2 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) PHD PF00628.29 CEH16589.1 - 1e-05 25.3 18.4 1.7e-05 24.6 18.4 1.4 1 0 0 1 1 1 1 PHD-finger UNC-79 PF14776.6 CEH16589.1 - 0.44 9.3 3.1 0.68 8.6 3.1 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Pet127 PF08634.10 CEH16591.1 - 4.9e-92 308.2 0.0 7e-92 307.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 POP1 PF06978.11 CEH16592.1 - 1.8e-21 77.1 14.5 1.8e-21 77.1 14.5 4.4 3 1 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CEH16592.1 - 1.1e-20 73.8 0.0 4e-20 71.9 0.0 2.0 1 0 0 1 1 1 1 POPLD (NUC188) domain Synaptonemal_3 PF15191.6 CEH16592.1 - 0.043 13.6 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 GCV_T_C PF08669.11 CEH16592.1 - 0.071 13.0 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DUF1541 PF07563.11 CEH16592.1 - 0.13 12.2 1.2 0.29 11.0 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Hydrolase_6 PF13344.6 CEH16593.1 - 6.8e-32 109.6 0.0 1.3e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEH16593.1 - 4.8e-18 65.0 0.0 8.6e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CEH16593.1 - 9.8e-07 29.3 0.0 1.2e-05 25.7 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEH16593.1 - 1.5e-05 25.1 0.2 0.068 13.3 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Telomere_Sde2_2 PF13297.6 CEH16593.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Telomere stability C-terminal PGP_phosphatase PF09419.10 CEH16593.1 - 0.03 13.9 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 CEH16593.1 - 0.032 13.8 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) ACOX PF01756.19 CEH16594.1 - 1.6e-41 141.9 0.0 3.2e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CEH16594.1 - 2.2e-25 89.6 0.0 3.7e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CEH16594.1 - 5.9e-13 48.8 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CEH16594.1 - 0.0014 18.8 0.3 0.0071 16.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEH16594.1 - 0.058 14.0 0.0 0.38 11.4 0.0 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Gag_p19 PF02228.16 CEH16594.1 - 0.13 12.7 0.0 0.65 10.5 0.0 2.2 2 0 0 2 2 2 0 Major core protein p19 DUF4887 PF16228.5 CEH16595.1 - 0.11 12.6 2.2 0.38 10.9 2.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Ysc84 PF04366.12 CEH16596.1 - 1.6e-42 144.3 0.2 1.6e-42 144.3 0.2 2.0 3 0 0 3 3 3 1 Las17-binding protein actin regulator Metallophos PF00149.28 CEH16597.1 - 7.3e-36 124.6 0.1 1.3e-35 123.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEH16597.1 - 0.078 13.4 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Ubie_methyltran PF01209.18 CEH16598.1 - 4.2e-68 229.2 0.0 1.6e-37 129.1 0.0 2.3 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CEH16598.1 - 1.2e-13 51.5 0.0 1.2e-05 25.9 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 CEH16598.1 - 4.4e-12 46.5 0.0 6.7e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CEH16598.1 - 6.6e-11 42.8 0.0 1.3e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH16598.1 - 1.2e-09 38.1 0.0 0.00012 21.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CEH16598.1 - 8.8e-06 25.6 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CEH16598.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase vATP-synt_AC39 PF01992.16 CEH16599.1 - 6.2e-103 344.8 0.0 7.6e-103 344.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit ANAPC4 PF12896.7 CEH16600.1 - 4.8e-13 49.1 0.3 9e-13 48.2 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 CEH16600.1 - 0.036 14.3 1.5 0.067 13.5 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Trypsin_2 PF13365.6 CEH16601.1 - 0.018 16.0 0.1 0.026 15.4 0.1 1.2 1 0 0 1 1 1 0 Trypsin-like peptidase domain PHD PF00628.29 CEH16602.1 - 3.9e-07 29.9 7.1 7.4e-07 29.0 7.1 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 CEH16602.1 - 1.7e-05 24.7 3.5 2.9e-05 23.9 3.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 CEH16602.1 - 0.0096 16.2 0.7 0.023 15.0 0.7 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-RING_9 PF13901.6 CEH16602.1 - 0.074 13.0 0.7 0.16 12.0 0.7 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon WSD PF15613.6 CEH16602.1 - 0.15 12.5 0.0 0.15 12.5 0.0 2.9 3 1 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF2754 PF10953.8 CEH16602.1 - 0.2 11.9 0.0 0.46 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) ADH_zinc_N PF00107.26 CEH16605.1 - 1.8e-12 47.3 0.3 6.1e-12 45.6 0.3 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH16605.1 - 1.4e-08 34.6 0.1 4.8e-08 32.8 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CEH16605.1 - 0.00012 23.1 0.0 0.00024 22.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MBOAT_2 PF13813.6 CEH16606.1 - 9.2e-08 32.3 0.9 2.2e-07 31.0 0.9 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family zf-CCHC PF00098.23 CEH16607.1 - 3e-07 30.2 1.0 5.9e-07 29.3 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEH16607.1 - 0.00017 21.3 2.2 0.00031 20.5 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CEH16607.1 - 0.00022 21.4 0.1 0.00022 21.4 0.1 3.0 3 1 1 4 4 4 1 Retrotransposon gag protein zf-CCHC_5 PF14787.6 CEH16607.1 - 0.00044 19.9 1.7 0.0012 18.5 1.7 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Asp_protease_2 PF13650.6 CEH16607.1 - 0.13 12.9 0.0 0.38 11.4 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF3802 PF12290.8 CEH16607.1 - 2 8.9 5.8 5.8 7.5 4.9 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) RT_RNaseH_2 PF17919.1 CEH16608.1 - 3.6e-38 129.6 0.0 7e-38 128.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEH16608.1 - 1.3e-37 128.3 0.1 2.9e-37 127.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEH16608.1 - 6.3e-21 74.2 0.0 1.3e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CEH16608.1 - 7.8e-21 74.6 0.3 2.7e-20 72.9 0.3 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 CEH16608.1 - 1.8e-14 53.4 0.6 3.6e-14 52.4 0.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CEH16608.1 - 0.012 15.8 0.0 0.047 13.9 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Phage_mat-A PF03863.13 CEH16609.1 - 0.0028 16.7 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Phage maturation protein Sugar_tr PF00083.24 CEH16613.1 - 1.6e-106 356.9 16.6 5.7e-106 355.1 16.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH16613.1 - 3.2e-24 85.5 27.8 2.4e-15 56.4 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PIP5K PF01504.18 CEH16615.1 - 2.6e-96 322.0 0.0 1.2e-95 319.8 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase adh_short PF00106.25 CEH16618.1 - 2.6e-44 151.0 0.0 1.6e-37 128.9 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEH16618.1 - 2.7e-41 141.7 0.0 7e-37 127.2 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH16618.1 - 3.4e-07 30.4 0.4 5.5e-07 29.7 0.4 1.4 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 CEH16618.1 - 0.032 14.3 0.2 0.092 12.8 0.1 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain LigB PF02900.18 CEH16619.1 - 9.1e-24 84.0 0.0 1.2e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase KdpA PF03814.15 CEH16619.1 - 0.27 9.4 0.0 0.38 8.9 0.0 1.1 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit HHH_8 PF14716.6 CEH16624.1 - 0.11 12.8 0.2 0.19 12.1 0.2 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain Voltage_CLC PF00654.20 CEH16626.1 - 2.1e-88 296.9 30.5 3.2e-88 296.4 30.5 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 CEH16626.1 - 3.4e-12 46.6 0.0 6.4e-06 26.5 0.0 2.8 2 0 0 2 2 2 2 CBS domain UPF0220 PF05255.11 CEH16626.1 - 0.25 10.9 3.0 0.75 9.3 3.0 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) Ras PF00071.22 CEH16627.1 - 2.2e-34 118.4 0.1 2.6e-34 118.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH16627.1 - 2.4e-26 92.3 0.0 3.5e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH16627.1 - 4.1e-08 32.9 0.0 5.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEH16627.1 - 7.5e-07 28.7 0.1 9.6e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 CEH16627.1 - 0.00017 20.5 0.0 0.12 11.1 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 CEH16627.1 - 0.017 14.3 0.4 0.089 11.9 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 CEH16627.1 - 0.051 13.0 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEH16627.1 - 0.053 13.6 0.0 0.079 13.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 CEH16627.1 - 0.12 11.8 0.0 1.8 7.9 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein PHP_C PF13263.6 CEH16627.1 - 0.16 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 PHP-associated DUF2554 PF10829.8 CEH16628.1 - 0.018 15.4 0.5 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) Baculo_PEP_C PF04513.12 CEH16629.1 - 0.02 15.0 1.7 0.033 14.2 1.7 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMP_2 PF06791.13 CEH16629.1 - 0.27 10.9 3.0 0.35 10.5 2.5 1.5 1 1 1 2 2 2 0 Prophage tail length tape measure protein Caveolin PF01146.17 CEH16629.1 - 4.8 7.2 5.9 6.3 6.8 0.3 2.2 1 1 0 2 2 2 0 Caveolin Amino_oxidase PF01593.24 CEH16630.1 - 4.8e-17 62.4 0.0 6e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase G-alpha PF00503.20 CEH16631.1 - 8.9e-102 340.9 0.0 1e-101 340.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEH16631.1 - 9.7e-12 44.7 0.2 8.9e-07 28.5 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 CEH16631.1 - 0.033 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 CEH16631.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 CEH16631.1 - 0.036 13.4 0.5 6.6 6.0 0.1 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF2231 PF09990.9 CEH16631.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) Glyco_transf_28 PF03033.20 CEH16633.1 - 2.6e-18 66.4 0.0 6.4e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 CEH16633.1 - 5.5e-06 26.8 0.0 0.00013 22.5 0.0 2.6 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 CEH16633.1 - 0.00014 20.9 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GRAM PF02893.20 CEH16633.1 - 0.00061 19.6 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 2 GRAM domain Prenyltransf PF01255.19 CEH16633.1 - 0.005 16.4 0.0 0.038 13.5 0.0 2.3 3 0 0 3 3 3 1 Putative undecaprenyl diphosphate synthase PH_BEACH PF14844.6 CEH16633.1 - 0.048 13.8 0.0 21 5.3 0.0 3.0 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH DUF4081 PF13312.6 CEH16633.1 - 0.31 11.2 2.6 1.7 8.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4081) dCMP_cyt_deam_1 PF00383.23 CEH16634.1 - 2.6e-07 30.5 0.2 0.00012 21.9 0.0 2.7 2 1 1 3 3 3 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEH16634.1 - 0.028 14.2 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 MafB19-like deaminase DnaJ PF00226.31 CEH16635.1 - 0.0031 17.6 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CEH16635.1 - 0.014 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Pam16 Transp_cyt_pur PF02133.15 CEH16636.1 - 6.9e-23 81.1 20.3 6.9e-23 81.1 20.3 2.3 3 0 0 3 3 3 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4658 PF15555.6 CEH16636.1 - 8.1 6.6 6.3 11 6.1 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Kelch_4 PF13418.6 CEH16637.1 - 1.5e-26 92.1 6.8 2.5e-05 24.2 0.0 7.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CEH16637.1 - 3.2e-25 87.8 8.5 1.4e-05 25.2 2.5 7.5 7 1 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.6 CEH16637.1 - 4.1e-19 68.4 0.1 4.1e-19 68.4 0.1 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.6 CEH16637.1 - 3.3e-17 62.1 5.2 0.00018 21.4 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 CEH16637.1 - 6.1e-15 54.9 4.7 8.6e-05 22.7 0.0 5.8 6 1 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CEH16637.1 - 6.1e-09 35.5 3.6 4.8e-05 23.2 0.1 4.8 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 CEH16637.1 - 3.1e-07 29.9 6.7 9.4e-05 21.9 0.1 4.5 4 1 0 4 4 4 2 Kelch motif Paramyxo_ncap PF00973.19 CEH16637.1 - 0.12 11.3 0.6 0.27 10.1 0.6 1.5 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein LIP PF03583.14 CEH16638.1 - 2e-52 178.3 0.0 2.8e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase DUF829 PF05705.14 CEH16638.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Mito_carr PF00153.27 CEH16641.1 - 2.6e-33 113.8 1.9 2.7e-17 62.5 0.3 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.27 CEH16642.1 - 2.1e-11 43.6 0.1 2.3e-11 43.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein SKN1 PF03935.15 CEH16645.1 - 1.8e-176 587.5 0.0 2.6e-176 586.9 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) UQ_con PF00179.26 CEH16647.1 - 9e-44 148.5 0.0 1e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEH16647.1 - 0.0073 16.0 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CEH16647.1 - 0.0098 16.2 0.4 0.017 15.4 0.3 1.5 1 1 0 1 1 1 1 RWD domain Cyt-b5 PF00173.28 CEH16648.1 - 6.6e-19 67.8 3.0 7.9e-19 67.6 0.1 2.4 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 CEH16648.1 - 8.3e-15 55.3 15.8 8.3e-15 55.3 15.8 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3100 PF11299.8 CEH16648.1 - 0.65 9.4 4.7 0.55 9.6 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3100) Ribosomal_L5e PF17144.4 CEH16650.1 - 5.6e-77 257.3 0.0 5.6e-77 257.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CEH16650.1 - 2.4e-29 102.1 6.6 2.4e-29 102.1 6.6 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 CEH16650.1 - 0.003 17.9 0.5 0.0056 17.0 0.1 1.6 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thr_synth_N PF14821.6 CEH16650.1 - 0.012 15.8 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Threonine synthase N terminus Ribosomal_L15e PF00827.17 CEH16651.1 - 1.3e-87 292.5 7.3 1.5e-87 292.3 7.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 Cys_Met_Meta_PP PF01053.20 CEH16653.1 - 2.9e-116 388.1 0.0 6.1e-112 373.9 0.0 2.1 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CEH16653.1 - 0.0058 15.8 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 CEH16653.1 - 0.0077 14.8 0.0 0.01 14.4 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase DUF4971 PF16341.5 CEH16653.1 - 0.14 11.9 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) Glyco_hydro_3_C PF01915.22 CEH16654.1 - 6.9e-47 160.0 0.0 1.1e-46 159.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CEH16654.1 - 4.1e-37 128.2 0.0 2.2e-24 86.4 0.0 2.7 2 1 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CEH16654.1 - 1.7e-15 56.9 0.0 3.5e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ThuA PF06283.11 CEH16655.1 - 2e-42 145.8 0.0 2.4e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Trehalose utilisation Rtt106_N PF18215.1 CEH16655.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain TPR_1 PF00515.28 CEH16656.1 - 7.2e-23 79.4 1.9 1.9e-08 33.7 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEH16656.1 - 2.4e-22 77.2 14.4 1.1e-06 28.3 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEH16656.1 - 1.4e-16 59.9 4.2 0.00028 20.5 0.1 4.6 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 CEH16656.1 - 5.7e-15 54.2 4.7 0.00093 19.2 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEH16656.1 - 2.3e-12 46.6 23.4 0.00025 21.6 1.8 7.1 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEH16656.1 - 1.1e-11 45.0 10.2 0.0021 18.5 0.3 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEH16656.1 - 2e-09 37.9 17.6 1.3e-05 25.8 0.1 5.3 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEH16656.1 - 3.3e-09 36.9 10.4 0.047 14.0 0.0 4.8 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEH16656.1 - 4.3e-09 36.1 5.0 0.0004 20.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEH16656.1 - 2.1e-05 24.2 7.1 0.12 12.4 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEH16656.1 - 0.00024 21.5 9.0 5 8.0 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEH16656.1 - 0.00074 19.6 3.4 0.29 11.3 0.2 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH16656.1 - 0.0019 18.4 6.0 0.0061 16.8 0.6 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CEH16656.1 - 0.003 16.8 1.8 1.4 8.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Coatomer_E PF04733.14 CEH16656.1 - 0.007 15.8 1.1 0.4 10.0 0.2 3.0 2 1 0 2 2 2 1 Coatomer epsilon subunit LAL_C2 PF18603.1 CEH16656.1 - 0.026 14.7 2.4 8.5 6.6 0.0 3.6 4 0 0 4 4 4 0 L-amino acid ligase C-terminal domain 2 TPR_3 PF07720.12 CEH16656.1 - 0.15 12.1 0.0 2.4 8.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Nucleoporin_FG2 PF15967.5 CEH16656.1 - 0.23 9.9 8.2 0.38 9.2 8.2 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeated region TPR_10 PF13374.6 CEH16656.1 - 0.35 10.8 13.4 0.59 10.1 0.1 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CEH16656.1 - 0.43 10.5 4.0 6.1 6.7 0.1 2.7 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal SHNi-TPR PF10516.9 CEH16656.1 - 0.62 9.6 3.6 69 3.0 0.1 3.7 3 0 0 3 3 3 0 SHNi-TPR BTAD PF03704.17 CEH16656.1 - 2.3 8.6 20.5 2.1 8.8 6.0 4.3 4 1 0 5 5 4 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 CEH16656.1 - 5.2 7.5 20.0 0.73 10.2 0.6 4.8 5 1 1 6 6 4 0 Tetratricopeptide repeat MIT PF04212.18 CEH16656.1 - 8.2 6.6 10.3 4.7 7.4 0.0 4.4 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain NDK PF00334.19 CEH16658.1 - 4.8e-53 178.8 0.0 6e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Peptidase_S9 PF00326.21 CEH16659.1 - 1.8e-05 24.3 0.3 5.4e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CEH16659.1 - 0.0072 15.6 0.4 0.077 12.3 0.0 2.4 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Sld5 PF05916.11 CEH16660.1 - 0.061 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 GINS complex protein DSBA PF01323.20 CEH16661.1 - 3.1e-06 27.1 0.4 2.5e-05 24.1 0.2 1.9 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 CEH16661.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin SSP160 PF06933.11 CEH16662.1 - 0.45 8.7 17.3 0.46 8.6 17.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SOG2 PF10428.9 CEH16662.1 - 3.1 6.9 12.8 3.3 6.8 12.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 CEH16662.1 - 3.7 6.3 6.8 4 6.2 6.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Arrestin_C PF02752.22 CEH16664.1 - 1.2e-09 38.7 0.8 1e-07 32.5 0.2 2.7 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEH16664.1 - 0.00022 21.3 0.2 0.43 10.6 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain PGBA_C PF15437.6 CEH16664.1 - 9.3 6.7 26.7 5.8 7.4 0.5 4.5 4 0 0 4 4 4 0 Plasminogen-binding protein pgbA C-terminal Ribosomal_L24e PF01246.20 CEH16665.1 - 6.9e-33 112.7 0.7 1.7e-32 111.4 0.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e DUF4407 PF14362.6 CEH16665.1 - 0.61 9.4 6.5 0.71 9.2 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_E PF05680.12 CEH16665.1 - 2.9 8.3 9.6 8.2 6.8 9.2 1.8 1 1 1 2 2 2 0 ATP synthase E chain Ribosomal_L38e PF01781.18 CEH16666.1 - 1.9e-35 120.7 1.9 2.8e-35 120.2 1.9 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family Ribosomal_L18p PF00861.22 CEH16666.1 - 0.031 14.6 0.2 0.061 13.7 0.1 1.5 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast adh_short PF00106.25 CEH16667.1 - 1.4e-39 135.6 0.2 2.1e-39 135.0 0.1 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH16667.1 - 9.7e-28 97.3 0.1 1.4e-27 96.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH16667.1 - 1.2e-08 35.0 0.3 2.5e-08 34.0 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEH16667.1 - 0.00066 19.2 0.3 0.0015 18.1 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEH16667.1 - 0.0021 17.1 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 CEH16667.1 - 0.063 13.1 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MIP PF00230.20 CEH16672.1 - 1.3e-42 146.1 4.8 1.7e-42 145.7 4.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pirin PF02678.16 CEH16673.1 - 5.2e-30 103.6 0.1 1.1e-29 102.6 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 CEH16673.1 - 1.4e-16 60.7 0.0 2.6e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 CEH16673.1 - 0.0066 16.1 3.8 0.037 13.7 1.3 2.3 2 0 0 2 2 2 1 Cupin domain Hen1_Lam_C PF18441.1 CEH16675.1 - 0.035 13.9 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Hen1 La-motif C-terminal domain zf-C2H2 PF00096.26 CEH16676.1 - 8.5e-05 22.8 13.1 0.018 15.5 2.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEH16676.1 - 0.00043 20.6 1.5 0.00043 20.6 1.5 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-CHCC PF10276.9 CEH16676.1 - 0.027 14.5 0.2 0.053 13.6 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger domain zf-C2H2_4 PF13894.6 CEH16676.1 - 0.028 15.2 11.1 0.23 12.4 1.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger IBR PF01485.21 CEH16676.1 - 0.029 14.6 0.3 0.055 13.7 0.3 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_6 PF13912.6 CEH16676.1 - 0.34 11.0 1.8 0.77 9.8 1.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Sec23_trunk PF04811.15 CEH16677.1 - 1.9e-75 253.6 0.0 2.8e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CEH16677.1 - 5.4e-31 107.2 0.0 1e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CEH16677.1 - 5.1e-26 90.5 0.1 1.3e-25 89.2 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CEH16677.1 - 7.2e-16 58.0 6.2 1.4e-15 57.1 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CEH16677.1 - 3.2e-13 49.4 0.0 7.7e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat SUIM_assoc PF16619.5 CEH16677.1 - 0.063 13.3 2.6 0.16 12.0 2.6 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 tRNA-synt_1b PF00579.25 CEH16678.1 - 3.3e-72 243.3 0.0 4.3e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NCD1 PF04904.13 CEH16678.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) WH1 PF00568.23 CEH16679.1 - 8.6e-17 61.1 0.0 1.2e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 CEH16679.1 - 5e-09 36.4 0.0 9.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 CEH16679.1 - 0.0099 15.7 0.2 0.03 14.2 0.2 1.9 1 0 0 1 1 1 1 WH2 motif DCP1 PF06058.13 CEH16679.1 - 0.087 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family Flu_M1_C PF08289.11 CEH16679.1 - 0.13 12.5 0.5 0.58 10.4 0.0 2.2 2 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain Aa_trans PF01490.18 CEH16680.1 - 1.6e-31 109.5 28.9 2.1e-31 109.1 28.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEH16680.1 - 5.3e-06 25.7 9.1 5.3e-06 25.7 9.1 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Abhydrolase_9_N PF15420.6 CEH16680.1 - 0.0044 17.1 7.6 0.0044 17.1 7.6 3.5 3 2 1 4 4 4 2 Alpha/beta-hydrolase family N-terminus SGT1 PF07093.11 CEH16681.1 - 4.5e-40 137.7 26.5 6.9e-12 44.6 0.1 5.3 5 1 0 5 5 5 4 SGT1 protein Rabaptin PF03528.15 CEH16682.1 - 0.12 11.1 0.2 0.19 10.4 0.2 1.2 1 0 0 1 1 1 0 Rabaptin ODV-E18 PF10717.9 CEH16683.1 - 0.091 12.6 3.3 2.7 7.9 0.6 2.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 R3H-assoc PF13902.6 CEH16685.1 - 0.18 12.2 0.3 0.18 12.2 0.3 2.0 2 1 1 3 3 3 0 R3H-associated N-terminal domain Acetyltransf_3 PF13302.7 CEH16686.1 - 7.4e-23 81.7 0.0 1.1e-22 81.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEH16686.1 - 0.0045 16.9 0.0 0.039 13.9 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 CEH16686.1 - 0.008 15.9 3.1 1.4 8.6 1.8 2.8 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain cNMP_binding PF00027.29 CEH16687.1 - 6.3e-26 90.3 0.0 2.9e-12 46.5 0.0 5.4 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 CEH16687.1 - 5e-17 62.8 1.6 2.7e-11 44.0 1.1 3.1 2 0 0 2 2 2 2 Patatin-like phospholipase RNase_PH PF01138.21 CEH16688.1 - 4.9e-22 78.8 0.1 9.6e-22 77.9 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Kinesin PF00225.23 CEH16690.1 - 4.9e-46 157.2 0.0 1.7e-24 86.4 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CEH16690.1 - 8.1e-08 32.3 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding ATP-synt_B PF00430.18 CEH16690.1 - 0.13 12.4 3.7 0.36 10.9 3.7 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) HHV-5_US34A PF17087.5 CEH16692.1 - 0.19 11.9 0.7 0.19 11.9 0.7 2.0 1 1 1 2 2 2 0 Herpesvirus US34A protein family DSX_dimer PF08828.10 CEH16693.1 - 0.079 12.6 0.1 0.2 11.3 0.1 1.7 1 1 0 1 1 1 0 Doublesex dimerisation domain Get5_C PF18514.1 CEH16693.1 - 0.15 11.8 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Get5 C-terminal domain DUF5346 PF17281.2 CEH16694.1 - 0.049 13.7 0.1 0.12 12.4 0.0 1.6 2 1 1 3 3 3 0 Family of unknown function (DUF5346) DUF2477 PF10631.9 CEH16696.1 - 0.012 16.3 0.5 0.015 16.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Polyketide_cyc2 PF10604.9 CEH16697.1 - 4.7e-07 30.2 0.2 6.1e-07 29.8 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 CEH16697.1 - 0.011 16.0 0.4 0.016 15.4 0.3 1.4 1 1 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Suc_Fer-like PF06999.12 CEH16699.1 - 1.3e-34 119.8 0.0 5.3e-29 101.5 0.0 2.4 1 1 1 2 2 2 2 Sucrase/ferredoxin-like POTRA_1 PF08478.10 CEH16701.1 - 0.17 12.2 0.1 0.28 11.5 0.1 1.3 1 0 0 1 1 1 0 POTRA domain, FtsQ-type AhpC-TSA PF00578.21 CEH16702.1 - 1e-24 86.8 0.0 1.6e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEH16702.1 - 5.9e-12 45.5 0.0 1.5e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Redoxin Patatin PF01734.22 CEH16705.1 - 2e-20 73.9 0.0 5.8e-20 72.3 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Peptidase_M43 PF05572.13 CEH16707.1 - 1.2e-12 48.0 0.0 1.9e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CEH16707.1 - 0.0001 22.5 0.0 0.00048 20.3 0.0 1.9 1 1 1 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CEH16707.1 - 0.023 14.3 0.1 0.05 13.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Mito_carr PF00153.27 CEH16708.1 - 5.6e-41 138.4 1.7 1.8e-13 50.2 0.1 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein RSRP PF17069.5 CEH16708.1 - 2.1 7.8 29.1 5.2 6.6 24.2 2.5 3 0 0 3 3 3 0 Arginine/Serine-Rich protein 1 Sporozoite_P67 PF05642.11 CEH16708.1 - 7.1 4.6 11.7 11 4.0 11.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen eIF3_subunit PF08597.10 CEH16709.1 - 5.9e-40 137.7 15.7 6.8e-40 137.5 15.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Isy1 PF06246.12 CEH16709.1 - 0.016 14.7 3.6 0.062 12.9 0.0 2.2 2 0 0 2 2 2 0 Isy1-like splicing family HMG_box PF00505.19 CEH16709.1 - 0.12 12.8 0.2 0.12 12.8 0.2 2.6 3 0 0 3 3 3 0 HMG (high mobility group) box ERO1 PF04137.15 CEH16710.1 - 1.1e-125 419.5 0.0 1.6e-125 419.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) SPX PF03105.19 CEH16710.1 - 0.9 9.4 5.0 1.7 8.5 0.3 2.2 2 0 0 2 2 2 0 SPX domain CENP-C_C PF11699.8 CEH16711.1 - 2.8e-25 88.3 0.0 4.6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 CEH16711.1 - 0.00018 21.1 0.0 0.00036 20.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Bindin PF02084.15 CEH16711.1 - 0.06 13.6 0.3 0.06 13.6 0.3 3.4 3 1 1 4 4 4 0 Bindin Pyridoxal_deC PF00282.19 CEH16712.1 - 9.4e-16 57.5 0.0 1.1e-14 54.0 0.0 2.3 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CEH16712.1 - 5.1e-09 35.6 0.0 8.6e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CEH16712.1 - 5.8e-07 29.1 0.2 1e-06 28.3 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.21 CEH16712.1 - 0.037 12.7 0.0 0.061 12.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Cys_Met_Meta_PP PF01053.20 CEH16712.1 - 0.077 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 CEH16713.1 - 2.3e-37 128.8 0.0 3.7e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinetochor_Ybp2 PF08568.10 CEH16713.1 - 6.1e-11 41.5 0.0 1.6e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Pkinase_Tyr PF07714.17 CEH16713.1 - 2.3e-10 40.2 0.0 4.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEH16713.1 - 1.6e-05 25.0 0.0 1.6e-05 25.0 0.0 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEH16713.1 - 0.004 16.8 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CEH16713.1 - 0.051 12.3 0.0 0.16 10.7 0.0 1.8 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CEH16713.1 - 0.075 12.4 0.1 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_1 PF00561.20 CEH16714.1 - 4e-40 138.1 1.0 8.4e-20 71.5 0.1 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 CEH16714.1 - 0.09 12.9 0.1 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein CN_hydrolase PF00795.22 CEH16715.1 - 1.8e-36 125.8 0.0 3e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 CEH16715.1 - 1.3e-20 73.6 0.0 4.2e-19 68.6 0.0 2.2 1 1 0 1 1 1 1 NAD synthase RPEL PF02755.15 CEH16716.1 - 0.22 11.3 1.2 0.5 10.2 1.2 1.6 1 0 0 1 1 1 0 RPEL repeat MULE PF10551.9 CEH16717.1 - 1.6e-27 95.7 0.4 3.4e-27 94.7 0.4 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 CEH16717.1 - 0.013 14.4 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 Transposase, Mutator family PalH PF08733.10 CEH16718.1 - 0.00073 18.6 0.1 0.0011 18.0 0.1 1.2 1 0 0 1 1 1 1 PalH/RIM21 DUF4084 PF13321.6 CEH16718.1 - 0.1 12.2 0.2 0.15 11.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4084) Asn_synthase PF00733.21 CEH16719.1 - 3.1e-90 303.4 2.8 5.5e-55 187.5 0.3 2.4 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CEH16719.1 - 1.1e-37 128.7 0.0 1.7e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CEH16719.1 - 1.2e-30 106.5 0.0 3.3e-29 101.8 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CEH16719.1 - 0.00014 21.4 0.0 0.00028 20.4 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 CEH16719.1 - 0.036 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 CEH16719.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase DUF3237 PF11578.8 CEH16720.1 - 1.9e-21 76.5 0.0 2.2e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) GFA PF04828.14 CEH16721.1 - 1.4e-15 57.4 0.0 1.9e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Rhomboid PF01694.22 CEH16722.1 - 8.2e-21 74.6 8.1 8.2e-21 74.6 8.1 1.7 2 0 0 2 2 2 1 Rhomboid family IBN_N PF03810.19 CEH16723.1 - 1.5e-10 40.8 0.0 8.8e-10 38.4 0.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.10 CEH16723.1 - 4.6e-05 22.4 0.0 0.00011 21.2 0.0 1.6 1 0 0 1 1 1 1 Cse1 HEAT PF02985.22 CEH16723.1 - 0.019 15.2 0.0 0.49 10.8 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat Xpo1 PF08389.12 CEH16723.1 - 0.04 14.0 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 Exportin 1-like protein DNA_pol_phi PF04931.13 CEH16723.1 - 5.7 4.9 7.2 5.4 5.0 5.1 1.9 2 0 0 2 2 2 0 DNA polymerase phi Peptidase_S26 PF10502.9 CEH16724.1 - 2.2e-09 37.2 0.0 6.3e-06 26.0 0.0 2.5 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 CEH16724.1 - 2.9e-08 33.5 0.0 6.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like MFS_1 PF07690.16 CEH16725.1 - 3.4e-22 78.9 43.6 3.4e-22 78.9 43.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH16725.1 - 1.4e-10 40.7 26.2 4.5e-06 25.8 7.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1129 PF06570.11 CEH16725.1 - 0.35 10.3 3.9 0.11 12.0 0.2 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) AflR PF08493.10 CEH16726.1 - 0.0088 15.5 2.3 0.0088 15.5 2.3 2.2 2 1 0 2 2 2 1 Aflatoxin regulatory protein Peptidase_M28 PF04389.17 CEH16727.1 - 3e-33 115.2 0.0 8.1e-33 113.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 Phage_Coat_A PF05357.13 CEH16728.1 - 5.6e-05 22.8 0.4 7.8e-05 22.4 0.4 1.2 1 0 0 1 1 1 1 Phage Coat Protein A YSIRK_signal PF04650.17 CEH16728.1 - 0.9 9.5 4.0 1.4 8.9 4.0 1.3 1 0 0 1 1 1 0 YSIRK type signal peptide DUF3767 PF12597.8 CEH16729.1 - 6.1e-20 70.9 0.3 8e-20 70.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Lipase_3 PF01764.25 CEH16731.1 - 2e-24 86.1 0.0 3.1e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 CEH16731.1 - 0.0096 15.9 0.0 0.027 14.4 0.0 1.6 1 1 0 2 2 2 1 Cutinase Abhydrolase_6 PF12697.7 CEH16731.1 - 0.022 15.3 0.2 0.055 14.1 0.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 CEH16731.1 - 0.099 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CEH16731.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FUSC_2 PF13515.6 CEH16732.1 - 6.6e-18 65.0 8.6 6.6e-18 65.0 8.6 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 CEH16732.1 - 3e-10 39.3 1.4 3e-10 39.3 1.4 4.7 5 0 0 5 5 5 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 CEH16732.1 - 2.5e-08 34.0 0.0 6.7e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 CEH16732.1 - 1.3e-07 30.8 0.5 2e-05 23.7 0.3 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2076 PF09849.9 CEH16732.1 - 0.00016 21.8 11.2 0.00016 21.8 11.2 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 CEH16732.1 - 0.00082 19.4 4.8 0.0016 18.5 4.8 1.5 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CEH16732.1 - 0.047 13.7 1.5 0.081 13.0 1.5 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Phage_holin_3_6 PF07332.11 CEH16732.1 - 2.9 8.0 9.1 16 5.6 9.1 2.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ELO PF01151.18 CEH16733.1 - 1.4e-57 195.1 3.6 1.7e-57 194.9 3.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF218 PF02698.17 CEH16734.1 - 9.1e-15 54.8 0.0 3.1e-13 49.9 0.0 2.2 1 1 0 1 1 1 1 DUF218 domain CoA_binding_2 PF13380.6 CEH16735.1 - 0.011 16.3 0.0 0.14 12.7 0.0 2.2 2 0 0 2 2 2 0 CoA binding domain ATP-grasp_3 PF02655.14 CEH16735.1 - 0.12 12.4 0.0 0.51 10.4 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain Acatn PF13000.7 CEH16736.1 - 5.5e-159 530.2 19.4 3e-79 267.0 12.5 3.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Fumble PF03630.14 CEH16737.1 - 1.9e-118 395.5 0.0 2.9e-117 391.5 0.0 2.5 1 1 0 1 1 1 1 Fumble AAA_18 PF13238.6 CEH16738.1 - 0.00027 21.5 0.0 0.004 17.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CEH16738.1 - 0.0017 18.9 0.0 0.0033 17.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PRK PF00485.18 CEH16738.1 - 0.0034 17.1 0.1 0.04 13.7 0.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 CEH16738.1 - 0.017 15.5 0.7 0.07 13.5 0.2 2.2 2 1 0 2 2 2 0 AAA ATPase domain Cytidylate_kin PF02224.18 CEH16738.1 - 0.039 13.7 0.1 5.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase CbiA PF01656.23 CEH16738.1 - 0.045 13.8 0.0 0.092 12.8 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 CEH16738.1 - 0.077 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.10 CEH16738.1 - 0.091 12.2 0.1 0.58 9.6 0.0 2.0 1 1 1 2 2 2 0 Chromatin associated protein KTI12 CLP1_P PF16575.5 CEH16738.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 CEH16738.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.6 CEH16738.1 - 0.25 11.6 1.0 0.54 10.5 0.2 2.0 3 0 0 3 3 3 0 AAA domain p450 PF00067.22 CEH16739.1 - 1e-25 90.4 0.0 3.7e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 VATC PF18716.1 CEH16741.1 - 0.098 12.5 0.9 0.23 11.3 0.9 1.7 1 0 0 1 1 1 0 Vms1-associating treble clef domain Metallothio_Pro PF02069.16 CEH16741.1 - 0.16 12.2 1.9 0.32 11.3 1.9 1.4 1 0 0 1 1 1 0 Prokaryotic metallothionein PPP4R2 PF09184.11 CEH16741.1 - 0.39 10.3 0.0 0.39 10.3 0.0 2.2 3 0 0 3 3 3 0 PPP4R2 TraT PF05818.12 CEH16742.1 - 0.15 11.8 1.7 0.19 11.4 1.7 1.4 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein TFIIB PF00382.19 CEH16743.1 - 2.8e-30 104.1 4.3 2e-17 63.0 0.9 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CEH16743.1 - 1e-11 44.2 0.4 1.6e-11 43.5 0.4 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 CEH16743.1 - 0.0055 16.4 0.4 0.076 12.8 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEH16743.1 - 0.0065 16.5 0.1 1.6 8.9 0.0 2.5 2 1 0 2 2 2 2 Cyclin, C-terminal domain RB_B PF01857.20 CEH16743.1 - 0.015 15.4 0.4 0.036 14.1 0.4 1.8 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain SF-assemblin PF06705.11 CEH16743.1 - 0.062 12.6 0.3 0.097 12.0 0.3 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin AAA_2 PF07724.14 CEH16746.1 - 4.9e-42 143.9 0.0 2.1e-38 132.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CEH16746.1 - 1.1e-31 108.9 0.7 1.1e-31 108.9 0.7 2.7 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 CEH16746.1 - 8e-27 93.1 0.3 3e-26 91.3 0.0 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CEH16746.1 - 2.7e-20 73.2 0.0 5.8e-10 39.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEH16746.1 - 8.4e-12 45.3 0.1 2.4e-06 27.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CEH16746.1 - 1.8e-11 44.1 0.1 7e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 CEH16746.1 - 3.2e-07 30.2 0.2 0.00063 19.5 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_16 PF13191.6 CEH16746.1 - 7.7e-07 29.6 16.1 0.0069 16.8 8.0 5.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CEH16746.1 - 1.2e-06 28.8 9.1 0.016 15.5 0.6 5.2 3 2 1 4 4 3 2 AAA domain ATPase_2 PF01637.18 CEH16746.1 - 9.1e-06 25.7 1.3 0.048 13.6 0.0 3.2 3 1 0 4 4 2 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CEH16746.1 - 1.8e-05 25.3 0.1 0.21 12.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CEH16746.1 - 3.3e-05 23.5 0.0 0.32 10.5 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ResIII PF04851.15 CEH16746.1 - 0.00014 21.9 0.0 0.099 12.6 0.0 2.9 2 1 0 3 3 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 CEH16746.1 - 0.00017 20.9 0.0 0.0036 16.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.6 CEH16746.1 - 0.0002 21.4 0.0 0.36 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_6 PF12774.7 CEH16746.1 - 0.00023 20.3 0.0 0.0042 16.1 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_3 PF07726.11 CEH16746.1 - 0.00052 19.9 0.0 0.0069 16.3 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 CEH16746.1 - 0.00055 19.6 0.0 0.16 11.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 CEH16746.1 - 0.0011 18.5 0.1 0.42 10.0 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 CEH16746.1 - 0.0014 18.1 0.0 0.16 11.4 0.0 3.2 2 1 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 CEH16746.1 - 0.0018 18.6 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.6 CEH16746.1 - 0.0032 17.8 0.1 6.2 7.2 0.1 3.8 3 1 0 4 4 3 0 AAA domain TIP49 PF06068.13 CEH16746.1 - 0.0038 16.5 0.3 2.2 7.4 0.0 2.8 3 0 0 3 3 3 1 TIP49 P-loop domain DUF815 PF05673.13 CEH16746.1 - 0.0041 16.3 0.7 0.5 9.5 0.0 3.4 3 2 0 3 3 3 1 Protein of unknown function (DUF815) TsaE PF02367.17 CEH16746.1 - 0.0046 17.0 0.0 3.3 7.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CEH16746.1 - 0.0053 16.5 1.5 8.2 6.2 0.9 4.1 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain CbiA PF01656.23 CEH16746.1 - 0.0062 16.6 0.0 4.1 7.5 0.0 3.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 CEH16746.1 - 0.013 14.5 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 CEH16746.1 - 0.014 15.3 0.3 0.36 10.7 0.0 2.7 3 0 0 3 3 2 0 NACHT domain DUF853 PF05872.12 CEH16746.1 - 0.014 14.0 0.0 1.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Torsin PF06309.11 CEH16746.1 - 0.017 15.2 0.0 0.074 13.2 0.0 1.9 2 0 0 2 2 2 0 Torsin AAA_30 PF13604.6 CEH16746.1 - 0.02 14.6 4.1 1.8 8.2 0.2 3.5 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.6 CEH16746.1 - 0.022 14.5 0.0 7.9 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CEH16746.1 - 0.027 13.4 0.0 1 8.2 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain DNA_pol3_delta2 PF13177.6 CEH16746.1 - 0.059 13.1 0.0 2 8.2 0.0 2.7 2 1 0 2 2 2 0 DNA polymerase III, delta subunit AAA_28 PF13521.6 CEH16746.1 - 0.061 13.6 7.3 3 8.1 0.4 3.8 3 2 0 3 3 2 0 AAA domain AAA_33 PF13671.6 CEH16746.1 - 0.083 13.0 2.2 2.7 8.2 0.0 3.3 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 CEH16746.1 - 0.11 11.9 0.0 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein PilJ PF13675.6 CEH16746.1 - 0.12 12.4 5.8 2.6 8.1 2.7 3.6 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term AAA_23 PF13476.6 CEH16746.1 - 0.23 11.9 6.7 53 4.2 0.0 3.6 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CEH16746.1 - 0.26 11.4 2.5 20 5.2 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain MPS2 PF17060.5 CEH16746.1 - 0.34 10.1 6.4 0.11 11.7 3.3 1.7 2 0 0 2 2 2 0 Monopolar spindle protein 2 Spc7 PF08317.11 CEH16746.1 - 1.5 7.6 11.7 3.7 6.3 11.7 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 CEH16746.1 - 2.4 8.4 11.4 7.8 6.8 9.4 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.8 CEH16746.1 - 2.6 8.3 11.8 1.9 8.7 9.0 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1090 PF06476.12 CEH16746.1 - 2.6 8.2 9.2 3.8 7.7 7.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) V_ATPase_I PF01496.19 CEH16746.1 - 4 5.2 4.0 5.4 4.8 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 CEH16746.1 - 4.2 6.4 10.8 7.9 5.5 10.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YlqD PF11068.8 CEH16746.1 - 5 7.5 6.7 5.8 7.3 5.5 1.8 1 1 0 1 1 1 0 YlqD protein Cupin_1 PF00190.22 CEH16747.1 - 4.6e-38 130.2 0.0 3.9e-19 68.7 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CEH16747.1 - 1.1e-25 89.1 1.2 9.6e-15 54.1 0.3 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 CEH16747.1 - 5.9e-09 35.9 0.3 0.0031 17.4 0.1 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 CEH16747.1 - 2.5e-08 33.5 0.2 0.0013 18.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 CEH16747.1 - 6.8e-06 26.0 0.0 0.0039 17.1 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase RWP-RK PF02042.15 CEH16747.1 - 0.15 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 RWP-RK domain SBP56 PF05694.11 CEH16751.1 - 2.1e-11 43.3 0.0 2e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 CEH16751.1 - 0.0063 15.8 0.0 2 7.6 0.0 2.6 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.11 CEH16751.1 - 0.014 14.5 0.0 0.1 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Cellulase PF00150.18 CEH16752.1 - 2.9e-13 49.9 0.1 1.1e-12 48.0 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ERG4_ERG24 PF01222.17 CEH16753.1 - 6.3e-131 437.1 21.3 7.5e-131 436.8 21.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Sterol-sensing PF12349.8 CEH16753.1 - 0.52 10.1 7.7 1.9 8.3 0.8 3.0 3 0 0 3 3 3 0 Sterol-sensing domain of SREBP cleavage-activation Ras PF00071.22 CEH16755.1 - 1.7e-56 190.3 0.0 2e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH16755.1 - 2.6e-22 79.3 0.0 3.5e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH16755.1 - 6.9e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CEH16755.1 - 0.00036 20.0 0.0 0.00049 19.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DNA_pol_B PF00136.21 CEH16756.1 - 1.8e-152 508.3 0.2 2.6e-152 507.8 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CEH16756.1 - 3.2e-85 286.2 0.0 8e-85 284.9 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CEH16756.1 - 3.5e-16 59.4 5.9 8.1e-16 58.3 5.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CEH16756.1 - 0.0032 16.4 0.4 0.0078 15.1 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral zf-RING-like PF08746.11 CEH16756.1 - 0.031 14.6 1.2 0.1 12.9 1.2 1.9 1 0 0 1 1 1 0 RING-like domain RNase_H_2 PF13482.6 CEH16756.1 - 0.032 14.2 0.1 0.14 12.1 0.1 2.1 1 1 0 1 1 1 0 RNase_H superfamily Alg6_Alg8 PF03155.15 CEH16757.1 - 1.6e-115 386.9 10.0 3.4e-87 293.5 7.8 2.2 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Phage_term_sma PF07141.11 CEH16758.1 - 3 7.6 7.2 10 5.8 0.1 3.3 2 1 1 4 4 4 0 Putative bacteriophage terminase small subunit UPF0047 PF01894.17 CEH16760.1 - 6.9e-36 122.9 0.0 7.9e-36 122.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Hpt PF01627.23 CEH16761.1 - 1.3e-08 34.9 0.0 2.8e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Hpt domain Zn_clus PF00172.18 CEH16762.1 - 0.0062 16.6 7.8 0.014 15.5 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gpr1_Fun34_YaaH PF01184.19 CEH16763.1 - 2.8e-63 213.3 21.7 3.5e-63 213.0 21.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 CEH16764.1 - 1.9e-37 128.9 11.6 2.4e-37 128.6 11.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family EXS PF03124.14 CEH16764.1 - 0.039 13.3 1.6 0.049 12.9 1.6 1.2 1 0 0 1 1 1 0 EXS family Oxidored_q2 PF00420.24 CEH16764.1 - 0.51 10.0 9.2 5 6.8 0.0 3.5 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L EXS PF03124.14 CEH16765.1 - 3.4e-83 279.7 25.3 4.5e-83 279.3 25.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CEH16765.1 - 7.9e-49 167.6 8.7 7.9e-49 167.6 8.7 1.8 2 0 0 2 2 2 1 SPX domain FtsX PF02687.21 CEH16765.1 - 0.11 12.9 0.2 0.11 12.9 0.2 1.9 2 0 0 2 2 2 0 FtsX-like permease family DUF3309 PF11752.8 CEH16765.1 - 0.28 11.2 2.3 0.61 10.2 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Porin_3 PF01459.22 CEH16766.1 - 2.6e-63 214.0 1.0 2.9e-63 213.9 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF615 PF04751.14 CEH16767.1 - 0.064 13.2 0.9 0.12 12.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Phage_holin_3_6 PF07332.11 CEH16767.1 - 7.2 6.7 7.9 0.53 10.3 1.0 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Motile_Sperm PF00635.26 CEH16768.1 - 1.8e-25 88.9 0.1 3.4e-25 88.0 0.1 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 CEH16768.1 - 1.4e-05 25.2 0.1 3.4e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Pkinase PF00069.25 CEH16769.1 - 2.1e-25 89.6 0.0 2.6e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH16769.1 - 9.6e-13 48.0 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH16769.1 - 6.1e-08 31.8 0.0 8.1e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEH16769.1 - 0.0024 17.9 1.0 3.5 7.5 0.0 3.0 4 0 0 4 4 4 2 Phosphotransferase enzyme family DUF4719 PF15843.5 CEH16770.1 - 0.028 14.5 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Ras PF00071.22 CEH16771.1 - 5.7e-48 162.6 0.0 6.6e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH16771.1 - 1.5e-16 60.7 0.0 2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH16771.1 - 1.7e-05 24.3 0.0 1.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEH16771.1 - 2.8e-05 24.1 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CEH16771.1 - 0.00021 20.9 0.0 0.00064 19.3 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEH16771.1 - 0.0006 19.9 0.0 0.00093 19.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zip PF02535.22 CEH16772.1 - 6.9e-50 170.1 0.1 1.1e-49 169.4 0.1 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter ABC1 PF03109.16 CEH16775.1 - 2.8e-31 108.1 0.3 5.1e-31 107.3 0.3 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CEH16775.1 - 0.00044 19.9 0.1 0.00096 18.8 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 CEH16775.1 - 0.0026 17.2 0.0 0.039 13.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain WaaY PF06176.11 CEH16775.1 - 0.003 17.2 0.1 0.011 15.3 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 CEH16775.1 - 0.044 13.7 2.0 0.14 12.0 0.0 2.8 3 1 1 4 4 4 0 Phosphotransferase enzyme family Trp_oprn_chp PF09534.10 CEH16775.1 - 3.9 7.2 9.8 0.28 10.9 3.5 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Fer4 PF00037.27 CEH16776.1 - 3.3e-15 55.2 17.9 2.4e-09 36.6 6.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CEH16776.1 - 8.2e-13 48.7 11.0 1.3e-12 48.1 11.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CEH16776.1 - 4.4e-11 43.5 7.5 5.4e-06 27.3 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 CEH16776.1 - 3.9e-10 39.7 22.1 3.1e-07 30.4 12.6 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 CEH16776.1 - 9.7e-10 38.4 6.1 0.00017 21.7 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CEH16776.1 - 1.1e-09 38.2 10.3 2e-09 37.5 10.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 CEH16776.1 - 2.4e-08 34.4 2.2 0.0023 18.5 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CEH16776.1 - 5.7e-08 32.5 18.7 0.00047 20.1 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 CEH16776.1 - 3.9e-07 30.4 16.5 0.00032 21.1 10.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CEH16776.1 - 1.7e-06 27.7 13.2 0.0028 17.6 2.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CEH16776.1 - 4.3e-06 26.8 11.6 0.0006 20.1 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 CEH16776.1 - 0.00027 21.4 10.8 0.032 14.8 0.5 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 CEH16776.1 - 0.0013 18.9 8.3 0.11 12.7 1.3 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 CEH16776.1 - 0.01 16.7 16.9 0.014 16.3 4.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 CEH16776.1 - 0.18 12.0 7.2 1.5 9.1 0.4 2.5 1 1 1 2 2 2 0 c-SKI Smad4 binding domain ETF_QO PF05187.13 CEH16776.1 - 0.92 9.7 5.7 2.3 8.4 0.8 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 CEH16776.1 - 1 10.2 12.0 3.3 8.6 2.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 CEH16776.1 - 9.7 7.0 16.0 0.46 11.3 3.3 2.9 2 2 1 3 3 3 0 4Fe-4S single cluster domain N-SET PF11764.8 CEH16777.1 - 0.41 10.7 3.4 0.82 9.8 3.4 1.4 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N DSPc PF00782.20 CEH16778.1 - 2.2e-23 82.5 0.0 1.8e-22 79.6 0.0 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEH16778.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SAB PF04382.13 CEH16779.1 - 0.3 11.2 1.6 9.5 6.4 0.1 2.7 2 0 0 2 2 2 0 SAB domain RasGEF PF00617.19 CEH16780.1 - 3e-46 157.8 0.0 5.3e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CEH16780.1 - 2.6e-14 53.3 0.1 5.8e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif IL11 PF07400.11 CEH16780.1 - 0.11 12.2 0.1 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Interleukin 11 Radical_SAM_C PF16199.5 CEH16781.1 - 3.9e-29 100.5 0.0 8.1e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CEH16781.1 - 4.8e-18 66.1 0.1 1.5e-17 64.5 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CEH16781.1 - 9.7e-10 38.7 0.0 2.2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEH16781.1 - 6.3e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEH16781.1 - 0.032 14.6 0.1 0.073 13.5 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RRM_1 PF00076.22 CEH16782.1 - 6.9e-26 89.9 0.0 1.3e-09 37.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CEH16782.1 - 0.071 12.9 0.0 15 5.4 0.0 2.5 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain GAS2 PF02187.17 CEH16784.1 - 2.2e-09 37.2 0.0 6.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain FapA PF03961.13 CEH16784.1 - 0.091 11.3 0.1 0.33 9.5 0.1 1.9 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CEH16784.1 - 1.6 8.9 15.5 0.022 15.0 1.2 4.3 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Methyltransf_11 PF08241.12 CEH16785.1 - 3.6e-10 40.4 0.0 9.6e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH16785.1 - 2.5e-08 34.5 0.0 1e-07 32.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH16785.1 - 1e-06 29.4 0.0 2.4e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH16785.1 - 1.2e-06 28.4 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CEH16785.1 - 0.033 13.9 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 CEH16785.1 - 0.037 15.1 0.0 0.088 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 CEH16785.1 - 0.056 12.6 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_31 PF13847.6 CEH16785.1 - 0.17 11.7 0.0 1.6 8.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 CEH16785.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ecl1 PF12855.7 CEH16786.1 - 2.5e-05 25.5 10.9 2.5e-05 25.5 10.9 5.4 1 1 3 4 4 4 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 CEH16786.1 - 0.022 14.9 1.1 0.043 13.9 1.1 1.4 1 0 0 1 1 1 0 MYND finger DUF2116 PF09889.9 CEH16786.1 - 0.12 12.4 1.1 0.26 11.3 1.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RRM_1 PF00076.22 CEH16787.1 - 2.2e-31 107.5 0.0 8.8e-15 54.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEH16787.1 - 1.2e-10 41.3 0.0 5.1e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Pam16 PF03656.13 CEH16788.1 - 1.9e-20 73.2 0.2 2.8e-20 72.6 0.2 1.2 1 0 0 1 1 1 1 Pam16 BTB PF00651.31 CEH16789.1 - 0.0075 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Abhydrolase_6 PF12697.7 CEH16790.1 - 8e-05 23.3 2.0 0.00013 22.6 2.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEH16790.1 - 0.0034 17.1 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH16790.1 - 0.13 11.5 0.0 6.4 6.0 0.0 2.7 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Las1 PF04031.13 CEH16791.1 - 4.6e-45 153.5 1.7 7.9e-45 152.7 0.5 2.0 2 0 0 2 2 2 1 Las1-like DER1 PF04511.15 CEH16791.1 - 3.4e-39 134.8 2.2 4.7e-39 134.3 2.2 1.2 1 0 0 1 1 1 1 Der1-like family GCFC PF07842.12 CEH16792.1 - 3.8e-70 236.7 10.5 5.4e-70 236.2 10.5 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 CEH16792.1 - 2.2e-10 40.8 5.7 2.2e-10 40.8 5.7 3.2 2 1 1 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.23 CEH16792.1 - 4.7e-07 29.6 4.0 4.7e-07 29.6 4.0 2.1 2 0 0 2 2 2 1 G-patch domain TilS PF09179.11 CEH16792.1 - 0.023 15.2 2.2 0.023 15.2 2.2 2.2 2 0 0 2 2 2 0 TilS substrate binding domain Lyase_1 PF00206.20 CEH16793.1 - 9.6e-118 393.1 0.0 1.2e-117 392.7 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CEH16793.1 - 1.1e-18 67.4 0.6 3.3e-18 65.9 0.0 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus ADH_N PF08240.12 CEH16793.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 CEH16794.1 - 2.5e-32 112.2 32.6 7.7e-32 110.6 33.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2905 PF11146.8 CEH16794.1 - 0.15 12.2 5.9 2.1 8.6 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) Peptidase_M56 PF05569.11 CEH16795.1 - 1.6 7.9 6.0 0.28 10.4 0.4 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 Pro_isomerase PF00160.21 CEH16797.1 - 5.4e-48 163.2 0.0 7.3e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 CEH16798.1 - 2.4e-62 210.7 0.0 1.2e-61 208.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH16798.1 - 4.8e-37 127.6 0.0 1.5e-34 119.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH16798.1 - 0.0039 16.0 0.0 0.0059 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEH16798.1 - 0.014 14.4 0.3 0.23 10.3 0.1 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 CEH16798.1 - 0.031 13.6 0.0 0.064 12.6 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 CEH16798.1 - 0.031 13.3 0.3 0.051 12.6 0.3 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CEH16798.1 - 0.064 13.2 0.0 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.25 CEH16801.1 - 1e-21 77.3 0.0 1.6e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEH16801.1 - 6.1e-15 55.4 0.0 3.8e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH16801.1 - 2.9e-07 30.6 0.0 1.3e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 KR domain SRF-TF PF00319.18 CEH16802.1 - 2.5e-20 71.7 0.0 4.3e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Cut12 PF11500.8 CEH16803.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Cutinase PF01083.22 CEH16804.1 - 2.2e-12 47.3 0.0 2.9e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Cutinase DUF883 PF05957.13 CEH16805.1 - 0.0017 18.9 31.1 0.52 11.0 3.6 4.1 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 CEH16805.1 - 0.0061 16.5 26.3 0.011 15.7 26.3 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Folliculin PF11704.8 CEH16805.1 - 6 6.7 10.6 0.92 9.4 4.7 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport GMC_oxred_N PF00732.19 CEH16806.1 - 6.5e-41 140.6 0.0 4.4e-40 137.9 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEH16806.1 - 8e-25 88.0 0.0 1.5e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CEH16806.1 - 0.0072 16.5 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thr_synth_N PF14821.6 CEH16807.1 - 3.5e-23 81.6 0.0 1.1e-22 80.1 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 CEH16807.1 - 3.8e-18 65.9 0.1 1.2e-17 64.3 0.1 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KELK PF15796.5 CEH16807.1 - 0.17 12.4 0.1 0.17 12.4 0.1 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase tRNA-synt_2d PF01409.20 CEH16808.1 - 9.5e-45 153.0 0.0 8e-25 87.7 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CEH16808.1 - 2.2e-24 85.7 0.0 2.9e-23 82.1 0.0 2.5 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain DEAD PF00270.29 CEH16809.1 - 9.5e-44 149.2 0.0 3.4e-43 147.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH16809.1 - 6.7e-25 87.6 0.0 6.7e-24 84.4 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH16809.1 - 0.00047 20.2 0.0 0.0015 18.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 CEH16809.1 - 0.0027 17.7 1.1 0.005 16.9 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CEH16809.1 - 0.013 15.2 0.5 0.029 14.1 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle ERCC3_RAD25_C PF16203.5 CEH16809.1 - 0.041 13.1 0.1 0.041 13.1 0.1 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase zf-CCHC_2 PF13696.6 CEH16809.1 - 0.083 12.7 0.6 0.15 11.9 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2285 PF10074.9 CEH16809.1 - 0.11 13.1 3.0 0.33 11.6 3.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) PP2C PF00481.21 CEH16810.1 - 1.3e-77 261.0 0.0 2.9e-77 259.8 0.0 1.6 1 1 1 2 2 2 1 Protein phosphatase 2C Exo_endo_phos PF03372.23 CEH16811.1 - 4.1e-08 33.0 0.0 6.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DASH_Hsk3 PF08227.11 CEH16812.1 - 4.7e-15 55.7 1.8 6.4e-15 55.2 1.8 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Flg_bb_rod PF00460.20 CEH16812.1 - 0.056 13.4 2.4 0.14 12.2 2.4 1.7 1 0 0 1 1 1 0 Flagella basal body rod protein CH PF00307.31 CEH16814.1 - 1.9e-41 140.6 0.0 9.4e-22 77.3 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 CEH16814.1 - 5.6e-21 74.4 0.2 2.1e-20 72.5 0.0 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 CEH16814.1 - 8.7e-08 31.9 0.1 0.0007 19.4 0.0 3.1 2 1 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.21 CEH16814.1 - 0.0024 18.3 3.7 1.2 9.7 0.2 2.8 2 0 0 2 2 2 2 Spectrin repeat EF-hand_6 PF13405.6 CEH16814.1 - 0.0038 17.0 0.0 0.014 15.3 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_14 PF17959.1 CEH16814.1 - 0.17 12.3 0.0 4.7 7.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain GDA1_CD39 PF01150.17 CEH16815.1 - 4.4e-88 295.8 0.0 5.5e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Glyco_hydro_79C PF16862.5 CEH16816.1 - 3.5e-17 63.2 0.1 7.5e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain WD40 PF00400.32 CEH16817.1 - 1.5e-24 85.8 0.1 0.0024 18.7 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH16817.1 - 9.7e-13 48.2 0.1 0.0058 16.9 0.0 4.9 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 CEH16817.1 - 2.3e-08 34.1 0.0 6.3e-06 26.1 0.0 2.3 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 CEH16817.1 - 0.012 14.6 1.2 1.2 8.0 0.0 3.1 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CBF PF03914.17 CEH16818.1 - 2.7e-26 92.6 0.2 2.7e-26 92.6 0.2 2.5 3 0 0 3 3 3 1 CBF/Mak21 family BUD22 PF09073.10 CEH16818.1 - 0.24 10.7 13.9 0.093 12.1 1.0 3.1 3 0 0 3 3 3 0 BUD22 GOLD_2 PF13897.6 CEH16818.1 - 7 7.2 7.0 0.48 10.9 0.6 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Kei1 PF08552.11 CEH16821.1 - 5e-48 163.5 1.0 5e-48 163.5 1.0 1.4 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 Ribosomal_S24e PF01282.19 CEH16822.1 - 3.2e-31 107.1 0.0 3.2e-31 107.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S24e C9orf72-like PF15019.6 CEH16822.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 C9orf72-like protein family Ribosomal_S9 PF00380.19 CEH16823.1 - 6e-32 110.7 0.6 6.8e-32 110.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Acetyltransf_17 PF17668.1 CEH16823.1 - 0.024 15.5 0.0 0.033 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rpn3_C PF08375.11 CEH16824.1 - 2e-26 92.2 1.3 2e-26 92.2 1.3 2.7 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CEH16824.1 - 3.1e-22 79.1 0.1 1e-21 77.4 0.1 1.9 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CEH16824.1 - 0.055 13.6 0.5 0.17 12.1 0.5 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat RNA_pol_Rpc4 PF05132.14 CEH16824.1 - 9.4 6.7 8.5 26 5.2 8.5 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 TIP49 PF06068.13 CEH16825.1 - 4.7e-160 532.6 0.1 6.3e-160 532.1 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CEH16825.1 - 1.9e-22 79.2 0.1 4.4e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CEH16825.1 - 8.2e-11 42.5 0.1 1.1e-06 29.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEH16825.1 - 7.4e-09 35.5 0.0 6e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEH16825.1 - 3.2e-06 27.5 0.3 0.099 12.9 0.2 2.5 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CEH16825.1 - 2.7e-05 24.2 0.1 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEH16825.1 - 4.9e-05 23.8 0.1 0.00035 21.0 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CEH16825.1 - 0.00035 20.2 0.1 0.001 18.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CEH16825.1 - 0.0014 18.9 0.1 0.0025 18.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH16825.1 - 0.0018 18.6 1.4 0.061 13.7 1.4 2.4 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CEH16825.1 - 0.0029 17.4 0.0 2.8 7.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DnaB_C PF03796.15 CEH16825.1 - 0.0057 16.0 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain NACHT PF05729.12 CEH16825.1 - 0.006 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Mg_chelatase PF01078.21 CEH16825.1 - 0.0085 15.5 0.1 0.39 10.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 CEH16825.1 - 0.02 14.2 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 CEH16825.1 - 0.032 14.0 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 CEH16825.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CEH16825.1 - 0.075 13.0 0.0 0.73 9.8 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CEH16825.1 - 0.098 12.7 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CEH16825.1 - 0.099 13.2 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEH16825.1 - 0.21 11.1 0.1 0.73 9.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region PPP4R2 PF09184.11 CEH16826.1 - 2.8e-07 30.5 0.0 2.8e-07 30.5 0.0 3.2 3 1 0 3 3 3 1 PPP4R2 Trm112p PF03966.16 CEH16827.1 - 3.1e-17 62.9 0.0 4.3e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein PhnA_Zn_Ribbon PF08274.12 CEH16827.1 - 0.094 12.7 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon RIO1 PF01163.22 CEH16829.1 - 1.5e-38 132.3 0.4 2.4e-26 92.5 0.0 2.5 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 CEH16829.1 - 3.6e-19 68.7 0.0 1.2e-18 67.1 0.0 1.9 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 CEH16829.1 - 4.4e-06 26.8 0.7 0.0077 16.2 0.2 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CEH16829.1 - 5.1e-05 22.7 0.0 0.00088 18.7 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PHO4 PF01384.20 CEH16831.1 - 2.2e-99 332.7 22.9 2.5e-99 332.5 22.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family RseC_MucC PF04246.12 CEH16831.1 - 1.6 8.7 9.4 0.21 11.6 0.2 3.5 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC URO-D PF01208.17 CEH16832.1 - 1.1e-136 455.6 0.0 1.2e-136 455.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) ANAPC10 PF03256.16 CEH16833.1 - 6.7e-48 162.8 0.1 1.2e-47 162.0 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) SH PF01445.17 CEH16836.1 - 0.00031 20.6 2.2 0.018 15.0 0.0 2.4 2 0 0 2 2 2 2 Viral small hydrophobic protein Vma12 PF11712.8 CEH16836.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Na_Ala_symp PF01235.17 CEH16841.1 - 0.088 12.1 0.2 0.09 12.1 0.2 1.0 1 0 0 1 1 1 0 Sodium:alanine symporter family Prenyltransf PF01255.19 CEH16844.1 - 8.4e-68 228.2 0.0 9.9e-68 228.0 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Fcf1 PF04900.12 CEH16845.1 - 8.6e-21 74.2 3.1 1.6e-20 73.3 3.1 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CEH16845.1 - 0.007 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 PIN like domain SR-25 PF10500.9 CEH16845.1 - 0.11 12.0 9.1 0.27 10.8 9.1 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4787 PF16029.5 CEH16845.1 - 1 9.5 8.0 2.7 8.1 2.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4787) Herpes_capsid PF06112.11 CEH16845.1 - 5.5 7.0 12.6 10 6.2 12.6 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MMM1 PF10296.9 CEH16847.1 - 1e-06 28.1 0.0 1.4e-05 24.4 0.0 2.6 2 1 1 3 3 3 1 Maintenance of mitochondrial morphology protein 1 Spt20 PF12090.8 CEH16847.1 - 2.7 7.6 14.2 0.55 9.8 6.4 2.4 2 0 0 2 2 2 0 Spt20 family Phosphodiest PF01663.22 CEH16848.1 - 1.9e-08 34.3 0.2 8.5e-08 32.2 0.2 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Mito_fiss_reg PF05308.11 CEH16848.1 - 0.11 12.5 20.7 0.77 9.8 7.9 3.5 3 0 0 3 3 3 0 Mitochondrial fission regulator PRIMA1 PF16101.5 CEH16848.1 - 2 8.5 29.1 3.2 7.8 3.7 3.5 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 CEH16848.1 - 2.1 7.7 30.5 0.6 9.5 1.9 3.6 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal NUC153 PF08159.12 CEH16849.1 - 2.5e-10 40.0 9.3 8.1e-10 38.3 1.3 3.1 3 0 0 3 3 3 2 NUC153 domain Curto_V2 PF07325.11 CEH16849.1 - 3.7 7.4 5.0 19 5.2 0.0 2.9 3 0 0 3 3 3 0 Curtovirus V2 protein WBS_methylT PF12589.8 CEH16850.1 - 3.4e-22 79.0 4.7 3.4e-22 79.0 4.7 1.5 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 CEH16850.1 - 7.8e-12 45.7 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH16850.1 - 2.4e-10 41.0 0.0 4.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH16850.1 - 1.1e-07 32.5 0.0 2.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH16850.1 - 3.6e-06 26.9 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH16850.1 - 1.1e-05 25.3 0.0 2e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 CEH16850.1 - 0.0069 16.1 0.3 0.029 14.1 0.0 2.0 2 1 0 2 2 2 1 DNA methylase PCMT PF01135.19 CEH16850.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 CEH16850.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) EF-hand_1 PF00036.32 CEH16856.1 - 0.00043 19.6 2.0 0.088 12.4 0.1 2.7 2 0 0 2 2 2 2 EF hand PAN_4 PF14295.6 CEH16856.1 - 0.0014 18.5 0.3 0.0014 18.5 0.3 2.4 3 0 0 3 3 3 1 PAN domain EF-hand_8 PF13833.6 CEH16856.1 - 0.0053 16.6 1.0 1.7 8.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair PAN_1 PF00024.26 CEH16856.1 - 0.013 15.4 2.8 0.013 15.4 2.8 2.3 1 1 1 2 2 2 0 PAN domain EF-hand_6 PF13405.6 CEH16856.1 - 0.068 13.1 3.8 0.21 11.6 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 CEH16856.1 - 0.093 12.3 0.3 0.33 10.5 0.1 2.0 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 CEH16856.1 - 0.14 12.6 0.1 2.7 8.5 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair PAN_3 PF08277.12 CEH16856.1 - 1.2 9.0 5.0 0.29 11.0 0.1 2.5 3 0 0 3 3 3 0 PAN-like domain Glyco_hydro_18 PF00704.28 CEH16857.1 - 5.8e-72 243.1 0.2 7e-72 242.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 CEH16857.1 - 5.9e-10 39.5 20.5 1.6e-09 38.0 20.5 1.8 1 0 0 1 1 1 1 Chitin recognition protein Ank PF00023.30 CEH16858.1 - 5.2e-08 33.0 1.7 0.0023 18.3 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 CEH16858.1 - 5.7e-05 23.6 0.0 0.00074 20.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEH16858.1 - 7e-05 22.9 0.3 0.24 12.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 CEH16858.1 - 0.00035 21.1 0.0 0.23 12.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEH16858.1 - 0.0023 18.2 0.1 3.5 8.0 0.0 4.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) LysM PF01476.20 CEH16859.1 - 7.6e-38 128.3 0.1 1.5e-08 34.6 0.0 5.9 6 0 0 6 6 6 5 LysM domain TPR_2 PF07719.17 CEH16867.1 - 0.021 14.9 1.1 0.075 13.2 1.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEH16867.1 - 0.027 14.7 0.1 0.079 13.2 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEH16867.1 - 0.13 12.3 1.6 0.23 11.6 0.6 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CEH16867.1 - 0.14 12.9 1.7 0.83 10.4 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MerR-DNA-bind PF09278.11 CEH16867.1 - 0.42 11.2 6.3 0.99 10.0 0.2 3.3 3 0 0 3 3 3 0 MerR, DNA binding TFIIS_C PF01096.18 CEH16868.1 - 3.5e-16 58.8 1.8 3.5e-16 58.8 1.8 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CEH16868.1 - 5.1e-07 29.5 6.0 0.00025 20.8 0.1 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 CEH16868.1 - 1.6e-05 24.3 10.8 0.012 15.2 1.4 2.9 2 1 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.7 CEH16868.1 - 2.1e-05 24.4 6.7 0.011 15.7 0.1 2.9 2 1 1 3 3 3 2 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 CEH16868.1 - 0.00023 21.0 5.2 0.023 14.6 0.1 2.9 2 1 0 2 2 2 1 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.6 CEH16868.1 - 0.0033 17.8 6.6 0.016 15.6 0.1 3.5 4 0 0 4 4 3 1 Zinc-finger double domain zf-ribbon_3 PF13248.6 CEH16868.1 - 0.0051 16.2 15.7 0.76 9.3 3.4 4.1 3 1 0 3 3 3 2 zinc-ribbon domain IBR PF01485.21 CEH16868.1 - 0.0078 16.4 4.4 2 8.7 0.0 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain DNA_ligase_ZBD PF03119.16 CEH16868.1 - 0.01 15.9 9.3 0.027 14.5 0.8 3.2 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-TFIIB PF13453.6 CEH16868.1 - 0.014 14.7 0.9 0.014 14.7 0.9 3.0 2 1 0 2 2 2 0 Transcription factor zinc-finger Prok-RING_1 PF14446.6 CEH16868.1 - 0.016 15.1 8.8 0.045 13.7 1.0 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_7 PF02591.15 CEH16868.1 - 0.028 14.6 7.7 7.4 6.8 0.0 4.2 4 0 0 4 4 4 0 C4-type zinc ribbon domain HypA PF01155.19 CEH16868.1 - 0.042 13.9 5.2 2.9 8.0 5.2 2.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nudix_N_2 PF14803.6 CEH16868.1 - 0.058 13.3 11.0 0.47 10.4 2.3 3.6 2 2 1 3 3 3 0 Nudix N-terminal CpXC PF14353.6 CEH16868.1 - 0.064 13.3 6.3 16 5.6 0.1 3.9 2 1 2 4 4 4 0 CpXC protein zinc_ribbon_9 PF14369.6 CEH16868.1 - 0.094 13.0 10.4 11 6.3 0.0 3.9 3 1 1 4 4 4 0 zinc-ribbon Terminase_GpA PF05876.12 CEH16868.1 - 0.1 11.2 0.5 0.24 9.9 0.5 1.7 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zf-NADH-PPase PF09297.11 CEH16868.1 - 0.12 12.0 11.6 1.4 8.6 2.3 3.3 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Nop10p PF04135.12 CEH16868.1 - 0.15 12.1 3.7 0.65 10.1 0.2 3.1 2 1 1 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family zinc_ribbon_5 PF13719.6 CEH16868.1 - 0.16 11.7 0.5 0.16 11.7 0.5 3.3 3 1 0 3 3 3 0 zinc-ribbon domain Desulfoferrod_N PF06397.12 CEH16868.1 - 0.18 11.5 3.9 2.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain Ogr_Delta PF04606.12 CEH16868.1 - 0.23 11.5 7.8 0.63 10.1 2.1 3.1 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.10 CEH16868.1 - 0.25 11.5 15.3 2.4 8.4 0.5 4.0 2 2 2 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 CEH16868.1 - 0.26 11.3 13.1 0.42 10.6 3.7 3.4 2 2 1 3 3 3 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 CEH16868.1 - 0.29 11.1 9.3 5.1 7.1 2.0 3.4 3 1 0 3 3 2 0 PhnA Zinc-Ribbon zf-IS66 PF13005.7 CEH16868.1 - 0.29 11.6 13.2 0.79 10.2 1.1 3.6 3 1 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-ISL3 PF14690.6 CEH16868.1 - 0.34 11.6 11.3 3.1 8.5 0.1 3.8 3 1 1 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DNA_RNApol_7kD PF03604.13 CEH16868.1 - 0.35 10.6 11.5 0.53 10.0 2.2 3.6 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 CEH16868.1 - 0.35 10.8 14.3 10 6.1 0.2 4.2 3 1 1 4 4 4 0 zinc-ribbon domain HscB_4_cys PF18256.1 CEH16868.1 - 0.37 10.6 7.5 2.6 7.9 0.1 3.9 4 0 0 4 4 4 0 Co-chaperone HscB tetracysteine metal binding motif zf-LITAF-like PF10601.9 CEH16868.1 - 0.47 10.8 4.8 21 5.5 0.1 3.6 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain DUF3268 PF11672.8 CEH16868.1 - 0.48 10.8 4.7 0.69 10.3 0.6 2.5 2 1 0 2 2 2 0 zinc-finger-containing domain zf_C2H2_10 PF18414.1 CEH16868.1 - 1 8.9 5.3 7.3 6.2 0.8 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger zinc_ribbon_2 PF13240.6 CEH16868.1 - 1.1 9.0 18.5 1.4 8.7 2.8 3.8 4 0 0 4 4 4 0 zinc-ribbon domain PHD PF00628.29 CEH16868.1 - 1.4 8.9 7.6 1.6 8.7 0.4 2.7 2 1 0 2 2 2 0 PHD-finger zf-C4_Topoisom PF01396.19 CEH16868.1 - 1.8 8.4 13.9 5.7 6.8 5.2 3.5 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Rubredoxin PF00301.20 CEH16868.1 - 2.5 8.2 7.1 31 4.7 0.1 3.8 4 0 0 4 4 4 0 Rubredoxin NOB1_Zn_bind PF08772.11 CEH16868.1 - 2.5 8.3 10.8 5.3 7.3 1.6 3.2 2 2 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Zn_ribbon_recom PF13408.6 CEH16868.1 - 3 8.4 7.0 23 5.6 0.9 3.0 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-FPG_IleRS PF06827.14 CEH16868.1 - 3.1 7.7 11.8 2.6 8.0 0.9 3.4 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DUF35_N PF12172.8 CEH16868.1 - 4.5 7.3 9.6 21 5.1 0.1 3.7 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Ribosomal_S27e PF01667.17 CEH16868.1 - 4.7 7.0 9.6 3.1 7.6 0.1 3.2 3 1 1 4 4 3 0 Ribosomal protein S27 PADR1 PF08063.12 CEH16868.1 - 6.1 6.7 9.8 1.8 8.4 0.1 3.3 3 1 0 3 3 3 0 PADR1 (NUC008) domain zf-RRN7 PF11781.8 CEH16868.1 - 8.1 6.2 13.9 3.3 7.5 0.4 4.1 4 1 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_15 PF17032.5 CEH16868.1 - 9.2 7.1 10.5 1.3e+02 3.4 2.3 3.4 1 1 1 2 2 2 0 zinc-ribbon family Methyltransf_23 PF13489.6 CEH16869.1 - 8.1e-17 61.5 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CEH16869.1 - 8.2e-08 31.5 0.0 1.1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 CEH16869.1 - 3.5e-07 30.9 0.0 5.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH16869.1 - 2.6e-05 24.1 0.0 0.0001 22.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH16869.1 - 0.00029 21.4 0.0 0.00052 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH16869.1 - 0.026 15.2 0.0 0.042 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain zf-ANAPC11 PF12861.7 CEH16870.1 - 3.1e-30 104.1 7.1 3.9e-30 103.7 7.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CEH16870.1 - 2.6e-18 66.1 8.4 3.6e-18 65.6 8.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEH16870.1 - 5.3e-08 33.1 9.2 4e-07 30.3 9.2 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEH16870.1 - 1.5e-05 24.8 4.5 3.7e-05 23.5 4.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEH16870.1 - 3.7e-05 23.7 2.8 3.7e-05 23.7 2.8 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEH16870.1 - 0.0038 17.1 10.1 0.026 14.5 10.4 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 CEH16870.1 - 0.017 14.8 9.8 0.45 10.3 9.8 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 CEH16870.1 - 0.019 14.8 14.7 0.58 10.1 14.7 2.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CEH16870.1 - 0.036 14.2 10.4 0.14 12.4 10.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 CEH16870.1 - 0.068 13.0 2.2 0.1 12.4 2.2 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CEH16870.1 - 0.087 13.0 0.8 0.087 13.0 0.8 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CEH16870.1 - 0.37 10.7 9.1 4.5 7.2 9.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CEH16870.1 - 2.4 8.0 9.0 3.1 7.7 5.5 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 CEH16870.1 - 3 7.8 11.2 20 5.1 11.2 2.1 1 1 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 CEH16870.1 - 3.7 7.2 13.0 23 4.7 12.5 2.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Steroid_dh PF02544.16 CEH16871.1 - 5.5e-34 117.3 0.3 7.8e-34 116.8 0.3 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CEH16871.1 - 3.3e-05 23.5 0.2 4.7e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) YukD PF08817.10 CEH16871.1 - 0.00024 21.7 0.0 0.0004 21.0 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.23 CEH16871.1 - 0.0027 17.4 0.4 0.0049 16.6 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family PEMT PF04191.13 CEH16871.1 - 0.007 16.7 0.2 0.015 15.7 0.2 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase UAE_UbL PF14732.6 CEH16871.1 - 0.023 15.3 0.1 0.038 14.6 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UN_NPL4 PF11543.8 CEH16871.1 - 0.041 14.4 0.1 0.075 13.5 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 ICMT PF04140.14 CEH16871.1 - 0.043 14.2 0.7 0.091 13.2 0.1 1.9 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ubiquitin_4 PF18036.1 CEH16871.1 - 0.16 12.0 0.3 9.7 6.3 0.3 2.5 1 1 0 1 1 1 0 Ubiquitin-like domain TMA7 PF09072.10 CEH16873.1 - 2.1e-15 57.3 18.6 2.3e-15 57.1 18.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Arrestin_N PF00339.29 CEH16874.1 - 7.6e-06 26.0 0.0 2.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CEH16874.1 - 0.00035 21.0 0.0 0.0026 18.2 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Asp-B-Hydro_N PF05279.11 CEH16874.1 - 5.1 7.1 9.5 11 6.0 9.5 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AMP-binding PF00501.28 CEH16876.1 - 7e-69 232.4 0.0 5.7e-34 117.4 0.0 2.4 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CEH16876.1 - 3e-11 44.1 0.0 1.4e-10 41.9 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TMV_coat PF00721.21 CEH16876.1 - 0.05 13.4 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Virus coat protein (TMV like) UBX PF00789.20 CEH16877.1 - 1.1e-06 28.7 0.0 2.7e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain Hamartin PF04388.12 CEH16877.1 - 0.36 9.5 7.7 0.43 9.2 7.7 1.0 1 0 0 1 1 1 0 Hamartin protein Presenilin PF01080.17 CEH16877.1 - 5.1 5.7 8.6 6.7 5.4 8.6 1.2 1 0 0 1 1 1 0 Presenilin Abhydrolase_1 PF00561.20 CEH16878.1 - 4.8e-23 82.1 0.3 3.6e-19 69.4 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 CEH16878.1 - 1.2e-13 51.0 0.0 3.2e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Gemini_mov PF01708.16 CEH16878.1 - 0.091 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein Thioredoxin PF00085.20 CEH16879.1 - 7.1e-56 186.6 0.1 8.7e-27 93.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 CEH16879.1 - 5.2e-19 68.9 0.1 5.2e-19 68.9 0.1 3.3 4 1 0 4 4 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 CEH16879.1 - 1.8e-16 60.6 0.9 1.7e-07 31.6 0.0 3.1 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CEH16879.1 - 3.4e-15 56.2 0.0 2.4e-08 33.7 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family TraF PF13728.6 CEH16879.1 - 1.2e-09 38.3 3.6 7.6e-05 22.6 0.0 3.3 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 CEH16879.1 - 1.2e-08 35.2 0.3 0.16 12.3 0.0 4.3 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 CEH16879.1 - 9.6e-08 32.1 0.3 0.00022 21.3 0.1 2.9 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CEH16879.1 - 6.2e-07 29.4 0.0 0.0089 15.9 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.13 CEH16879.1 - 1.9e-06 28.1 0.8 0.037 14.2 0.0 2.5 2 0 0 2 2 2 2 ERp29, N-terminal domain Redoxin PF08534.10 CEH16879.1 - 6e-05 22.8 0.1 0.0074 16.0 0.0 2.5 2 0 0 2 2 2 1 Redoxin HyaE PF07449.11 CEH16879.1 - 0.00027 20.9 0.0 0.1 12.6 0.0 2.6 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 CEH16879.1 - 0.0056 16.5 3.6 0.079 12.7 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_4 PF13462.6 CEH16879.1 - 0.062 13.5 7.4 4.4 7.4 0.2 3.6 3 1 0 3 3 3 0 Thioredoxin Thioredoxin_5 PF13743.6 CEH16879.1 - 0.35 10.5 3.7 3.4 7.3 0.0 3.6 3 2 2 5 5 5 0 Thioredoxin Phasin PF05597.11 CEH16879.1 - 0.46 10.5 7.4 0.62 10.1 6.1 1.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YtxH PF12732.7 CEH16879.1 - 0.48 11.0 14.8 0.51 10.9 8.2 2.7 2 0 0 2 2 2 0 YtxH-like protein SOAR PF16533.5 CEH16879.1 - 2.2 8.3 5.8 0.72 9.9 1.8 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region Sec63 PF02889.16 CEH16880.1 - 6.1e-147 487.6 0.0 1e-78 264.1 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CEH16880.1 - 7.3e-45 152.9 0.0 1.4e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CEH16880.1 - 1.1e-33 115.7 0.1 6.3e-33 113.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 CEH16880.1 - 2.4e-23 83.0 0.0 1.7e-14 54.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEH16880.1 - 5.6e-11 42.8 0.0 7.5e-07 29.5 0.0 3.3 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CEH16880.1 - 1.4e-05 25.3 0.1 0.17 12.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CEH16880.1 - 0.00045 20.0 0.1 0.24 11.1 0.1 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 CEH16880.1 - 0.11 11.9 0.1 2 7.8 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein BUD22 PF09073.10 CEH16880.1 - 3.4 6.9 27.1 1.6 8.0 4.4 2.4 2 0 0 2 2 2 0 BUD22 RHD3 PF05879.12 CEH16881.1 - 1.6e-235 783.7 0.0 2e-235 783.4 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 CEH16881.1 - 3.7e-05 23.8 0.0 8.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CEH16881.1 - 0.00026 21.1 0.0 0.0009 19.3 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GBP PF02263.19 CEH16881.1 - 0.0012 18.2 0.1 0.0022 17.3 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 CEH16881.1 - 0.0057 16.9 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEH16881.1 - 0.21 11.9 2.6 0.73 10.2 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain DUF3254 PF11630.8 CEH16882.1 - 0.059 13.6 1.0 0.063 13.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) DUF3602 PF12223.8 CEH16883.1 - 5.7e-18 65.3 40.8 9.5e-10 39.0 8.1 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Glyoxal_oxid_N PF07250.11 CEH16884.1 - 4.1e-27 94.9 0.4 1.4e-13 50.7 0.1 4.5 4 1 0 4 4 4 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CEH16884.1 - 1.9e-18 66.6 0.0 4e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) SKG6 PF08693.10 CEH16884.1 - 0.098 12.1 6.2 0.22 11.0 6.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain stn_TNFRSF12A PF12191.8 CEH16884.1 - 0.14 12.3 1.1 0.28 11.4 0.1 1.9 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Adeno_E3_CR2 PF02439.15 CEH16884.1 - 0.31 10.8 2.1 0.62 9.9 2.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-CCHC PF00098.23 CEH16885.1 - 0.069 13.3 1.5 0.17 12.0 1.5 1.7 1 1 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 CEH16885.1 - 0.12 12.8 0.2 0.23 11.9 0.2 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G CaiF_GrlA PF07180.11 CEH16885.1 - 0.16 11.9 0.7 0.26 11.2 0.7 1.3 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator 6PF2K PF01591.18 CEH16886.1 - 2.5e-63 213.4 0.0 3.2e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEH16886.1 - 3.9e-21 75.6 0.0 4.4e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CEH16886.1 - 0.0003 21.0 0.0 0.00056 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain GluRS_N PF18466.1 CEH16886.1 - 0.05 14.0 0.1 0.18 12.2 0.1 2.0 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain KTI12 PF08433.10 CEH16886.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Linker_histone PF00538.19 CEH16888.1 - 6.4e-24 84.1 0.2 6.4e-24 84.1 0.2 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family Herpes_UL17 PF04559.12 CEH16888.1 - 6.5 5.4 7.3 8.2 5.1 7.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein SnoaL PF07366.12 CEH16889.1 - 6.6e-23 80.9 0.0 8.1e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 CEH16889.1 - 1.9e-08 34.8 0.0 3e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain VHS PF00790.19 CEH16890.1 - 4.3e-40 136.8 0.0 9.9e-40 135.6 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 CEH16890.1 - 3.8e-19 68.8 0.2 1.8e-18 66.6 0.0 2.3 3 0 0 3 3 3 1 GAT domain Exonuc_VII_L PF02601.15 CEH16890.1 - 0.0022 17.6 0.1 0.0047 16.5 0.0 1.4 1 1 0 1 1 1 1 Exonuclease VII, large subunit GGA_N-GAT PF18308.1 CEH16890.1 - 2.1 8.0 6.0 1.4 8.6 0.3 3.1 3 0 0 3 3 3 0 GGA N-GAT domain DIE2_ALG10 PF04922.12 CEH16891.1 - 6.8e-111 371.3 13.7 2.4e-86 290.5 11.8 2.1 2 0 0 2 2 2 2 DIE2/ALG10 family FA_desaturase PF00487.24 CEH16892.1 - 7.7e-15 55.4 26.2 1.2e-14 54.7 26.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CEH16892.1 - 1.9e-14 53.5 0.1 3.5e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cellulase PF00150.18 CEH16896.1 - 2.5e-07 30.4 0.0 4.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) S1-P1_nuclease PF02265.16 CEH16897.1 - 2.5e-43 148.7 0.1 7.9e-38 130.7 1.3 2.3 2 0 0 2 2 2 2 S1/P1 Nuclease Mem_trans PF03547.18 CEH16897.1 - 8.3e-32 110.0 6.3 8.9e-24 83.6 0.3 3.1 3 0 0 3 3 3 3 Membrane transport protein Herpes_DNAp_acc PF04929.12 CEH16897.1 - 0.35 9.8 2.9 0.74 8.7 2.9 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor IATP PF04568.12 CEH16897.1 - 0.81 10.1 5.0 13 6.3 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Snf7 PF03357.21 CEH16898.1 - 6.9e-31 107.1 16.8 6.9e-31 107.1 16.8 1.5 1 1 0 1 1 1 1 Snf7 Adenine_glyco PF03352.13 CEH16898.1 - 0.39 10.5 3.6 0.61 9.8 3.6 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase DUF4407 PF14362.6 CEH16898.1 - 9.5 5.5 13.2 95 2.2 13.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RNB PF00773.19 CEH16899.1 - 1.1e-48 166.3 0.0 3.8e-48 164.5 0.0 1.9 1 1 0 1 1 1 1 RNB domain SAC3_GANP PF03399.16 CEH16900.1 - 1.5e-93 313.4 0.0 2e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Nup84_Nup100 PF04121.13 CEH16901.1 - 1.5e-148 496.1 4.7 1.8e-148 495.8 4.7 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Wbp11 PF09429.10 CEH16902.1 - 1.4e-17 63.9 10.2 1.4e-17 63.9 10.2 2.2 3 0 0 3 3 3 1 WW domain binding protein 11 NpwBP PF12622.7 CEH16902.1 - 4e-07 30.7 29.6 4e-07 30.7 29.6 4.2 2 1 1 3 3 3 1 mRNA biogenesis factor TFIIE-A_C PF11521.8 CEH16902.1 - 3.2 8.1 8.5 0.37 11.1 3.2 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Rad52_Rad22 PF04098.15 CEH16903.1 - 4.6e-51 172.7 0.0 8.3e-51 171.9 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein eIF_4EBP PF05456.11 CEH16904.1 - 1.2e-11 44.6 5.5 3.6e-11 43.0 0.9 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) MutL_C PF08676.11 CEH16905.1 - 3.4e-08 33.4 0.1 5.4e-06 26.2 0.1 3.2 2 1 0 2 2 2 2 MutL C terminal dimerisation domain DUF4549 PF15082.6 CEH16906.1 - 0.097 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Tom22 PF04281.13 CEH16907.1 - 4.3e-37 127.0 0.4 5.8e-37 126.6 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 SANT_DAMP1_like PF16282.5 CEH16908.1 - 1.7e-32 111.4 2.6 2.9e-32 110.7 2.6 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Sec23_trunk PF04811.15 CEH16909.1 - 3.1e-53 180.8 0.0 1e-52 179.2 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CEH16909.1 - 2.4e-23 81.9 0.0 4.5e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CEH16909.1 - 7.2e-20 71.5 0.0 1.6e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CEH16909.1 - 5.6e-15 55.1 3.3 1.1e-14 54.1 3.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CEH16909.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat UPF1_Zn_bind PF09416.10 CEH16910.1 - 2.4e-70 235.4 3.6 4.4e-70 234.5 3.6 1.4 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CEH16910.1 - 2.1e-57 193.9 0.0 4.2e-57 193.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEH16910.1 - 1.9e-50 172.1 2.4 6.1e-29 101.6 0.2 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CEH16910.1 - 4.7e-31 106.9 0.2 1.2e-30 105.6 0.0 1.8 2 0 0 2 2 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CEH16910.1 - 1.8e-13 50.6 0.0 7.4e-13 48.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH16910.1 - 1.4e-10 41.7 0.1 4.6e-10 40.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 CEH16910.1 - 3.7e-05 23.8 0.0 6.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CEH16910.1 - 4.8e-05 22.8 0.9 0.0035 16.7 0.1 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 CEH16910.1 - 0.00015 21.6 0.1 0.43 10.3 0.0 3.2 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CEH16910.1 - 0.00035 20.5 0.0 0.00083 19.3 0.0 1.7 1 1 0 1 1 1 1 Helicase PIF1 PF05970.14 CEH16910.1 - 0.0014 17.9 0.1 0.081 12.1 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase ATPase PF06745.13 CEH16910.1 - 0.027 13.8 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 KaiC SRP54 PF00448.22 CEH16910.1 - 0.03 14.0 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CEH16910.1 - 0.04 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 CEH16910.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Ribosomal_S13_N PF08069.12 CEH16910.1 - 0.11 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain PhoH PF02562.16 CEH16910.1 - 0.15 11.5 0.0 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 CEH16910.1 - 0.16 11.8 0.4 0.29 10.9 0.4 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 CEH16910.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CEH16910.1 - 0.22 11.0 0.2 1.3 8.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 CEH16911.1 - 2.2e-17 63.7 0.0 4e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CEH16911.1 - 5.9e-12 45.7 0.0 7.3e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CEH16911.1 - 9.6e-10 38.8 0.0 2.6e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 CEH16911.1 - 3.2e-07 30.5 0.0 1.9e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 CEH16911.1 - 3.7e-06 27.3 0.1 0.00042 20.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEH16911.1 - 1.8e-05 24.7 0.0 3.1e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEH16911.1 - 2.9e-05 24.5 0.0 0.00086 19.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CEH16911.1 - 0.00031 20.5 0.0 0.00089 19.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CEH16911.1 - 0.00035 20.6 0.0 0.0007 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CEH16911.1 - 0.0006 19.8 0.0 0.0015 18.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CEH16911.1 - 0.00063 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEH16911.1 - 0.0007 19.4 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CEH16911.1 - 0.00098 19.4 0.0 0.0033 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 CEH16911.1 - 0.0012 18.3 0.1 0.036 13.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CEH16911.1 - 0.0028 17.2 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 CEH16911.1 - 0.0042 17.4 0.1 0.031 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 CEH16911.1 - 0.012 14.7 0.0 0.031 13.4 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain AAA_28 PF13521.6 CEH16911.1 - 0.012 15.8 0.0 0.028 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 CEH16911.1 - 0.012 15.3 0.2 0.092 12.5 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 CEH16911.1 - 0.014 15.4 0.0 0.14 12.1 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.11 CEH16911.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CEH16911.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CEH16911.1 - 0.025 13.7 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 CEH16911.1 - 0.028 14.9 0.0 0.084 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CEH16911.1 - 0.039 13.2 0.0 0.2 10.9 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CEH16911.1 - 0.079 12.4 0.1 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.6 CEH16911.1 - 0.094 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.28 CEH16913.1 - 2.2e-94 316.5 0.0 2.8e-94 316.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEH16913.1 - 6.1e-06 27.1 0.4 3.7e-05 24.6 0.2 2.5 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 CEH16914.1 - 4.3e-37 128.1 0.0 6.5e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II zf-CCCH PF00642.24 CEH16915.1 - 9.5e-06 25.4 11.9 0.0026 17.7 0.1 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CEH16915.1 - 8e-05 23.3 0.1 0.0062 17.2 0.0 2.7 2 0 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 CEH16915.1 - 0.016 15.0 1.3 0.016 15.0 1.3 2.9 3 0 0 3 3 3 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEH16915.1 - 0.023 14.8 0.6 0.023 14.8 0.6 2.9 3 0 0 3 3 3 0 Zinc finger domain zf-C3HC4_2 PF13923.6 CEH16915.1 - 0.24 11.3 1.8 0.56 10.1 1.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 CEH16915.1 - 0.51 10.9 3.8 0.44 11.1 0.7 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-RING_5 PF14634.6 CEH16915.1 - 1.1 9.3 5.8 2.5 8.1 5.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 CEH16915.1 - 4.5 7.7 11.2 1 9.7 7.3 2.0 2 0 0 2 2 2 0 Ring finger domain CN_hydrolase PF00795.22 CEH16916.1 - 2.5e-46 158.1 0.0 5.2e-46 157.1 0.0 1.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Git3 PF11710.8 CEH16918.1 - 0.003 17.3 1.7 0.0042 16.9 1.7 1.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 CEH16918.1 - 0.0079 15.6 0.0 0.0079 15.6 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3341 PF11821.8 CEH16918.1 - 0.1 12.2 2.9 0.15 11.7 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) GPR_Gpa2_C PF11970.8 CEH16919.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term HEAT_2 PF13646.6 CEH16923.1 - 0.011 16.2 0.2 0.013 15.8 0.2 1.1 1 0 0 1 1 1 0 HEAT repeats Abhydrolase_6 PF12697.7 CEH16926.1 - 1.9e-12 48.3 3.5 1.9e-12 48.3 3.5 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CEH16926.1 - 0.00016 21.9 0.1 0.00033 20.9 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 CEH16926.1 - 0.00053 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 CEH16926.1 - 0.0013 18.5 0.0 0.85 9.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH16926.1 - 0.0014 17.9 0.1 0.0042 16.4 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 CEH16926.1 - 0.014 15.3 0.1 0.028 14.3 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 CEH16926.1 - 0.07 12.7 0.0 8.4 5.9 0.0 2.5 3 0 0 3 3 3 0 Dienelactone hydrolase family Fungal_trans PF04082.18 CEH16928.1 - 9.2e-12 44.5 0.0 1.5e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH16928.1 - 0.00056 20.0 7.8 0.00093 19.3 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ceramidase_alk PF04734.13 CEH16930.1 - 1.6e-157 525.2 0.0 1.6e-111 373.5 0.0 4.0 2 1 1 3 3 3 3 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 CEH16930.1 - 2e-39 135.2 0.0 3.3e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Snf7 PF03357.21 CEH16931.1 - 8.1e-17 61.4 13.6 8.1e-17 61.4 13.6 1.7 2 0 0 2 2 2 1 Snf7 DASH_Spc34 PF08657.10 CEH16931.1 - 0.01 15.7 4.1 0.01 15.7 4.1 2.2 1 1 1 2 2 2 0 DASH complex subunit Spc34 DUF16 PF01519.16 CEH16931.1 - 2.7 8.5 7.0 0.38 11.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Dickkopf_N PF04706.12 CEH16933.1 - 9.8 6.8 8.4 9.2 6.8 5.5 2.1 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Catalase PF00199.19 CEH16934.1 - 2.2e-185 616.2 0.2 2.7e-185 616.0 0.2 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CEH16934.1 - 1.4e-17 63.6 0.0 3.4e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive TOM20_plant PF06552.12 CEH16934.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 GalP_UDP_transf PF01087.22 CEH16935.1 - 7.5e-64 215.6 0.0 1.1e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 CEH16935.1 - 2.1e-47 160.9 0.0 6.7e-47 159.3 0.0 1.9 2 1 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 CEH16935.1 - 2.9e-06 26.4 0.1 0.028 13.3 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4921) HIT PF01230.23 CEH16935.1 - 0.083 13.6 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 HIT domain THOC7 PF05615.13 CEH16937.1 - 0.0019 18.5 0.4 1.1 9.5 0.1 2.2 2 0 0 2 2 2 2 Tho complex subunit 7 Endotoxin_M PF00555.19 CEH16937.1 - 0.087 12.9 0.0 10 6.1 0.0 2.2 2 0 0 2 2 2 0 delta endotoxin Peroxidase_2 PF01328.17 CEH16938.1 - 3.2e-42 145.2 0.0 4.3e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Catalase PF00199.19 CEH16939.1 - 1.9e-144 481.5 1.0 2.6e-144 481.1 1.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CEH16939.1 - 9.5e-11 41.8 0.2 3e-10 40.2 0.2 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive Scm3 PF10384.9 CEH16940.1 - 6.3e-09 35.4 0.0 1.9e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Centromere protein Scm3 PI3Ka PF00613.20 CEH16941.1 - 2.5e-49 167.2 0.0 4.2e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CEH16941.1 - 1.4e-46 159.4 0.0 1.6e-30 106.7 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CEH16941.1 - 2.2e-26 92.4 0.0 3.5e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Zn_clus PF00172.18 CEH16942.1 - 1.1e-06 28.6 12.8 1.6e-06 28.1 12.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAP10 PF07213.11 CEH16943.1 - 0.0015 18.4 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 DAP10 membrane protein RCR PF12273.8 CEH16943.1 - 0.01 16.5 8.4 0.47 11.1 8.4 2.7 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 CEH16943.1 - 0.083 13.8 0.0 0.17 12.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5419 PF17441.2 CEH16943.1 - 0.12 12.5 0.4 24 5.1 0.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5419) Adeno_E3_CR2 PF02439.15 CEH16943.1 - 0.13 12.0 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 UCH PF00443.29 CEH16944.1 - 1.4e-43 149.2 0.0 1.8e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEH16944.1 - 3.2e-18 66.4 0.9 1.1e-17 64.6 0.9 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CEH16944.1 - 3.8e-09 36.7 7.1 3.8e-09 36.7 7.1 3.1 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein PEP-utilizers PF00391.23 CEH16944.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain zf-ribbon_3 PF13248.6 CEH16944.1 - 2 7.9 5.9 5 6.7 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain UreD PF01774.17 CEH16945.1 - 1.5e-44 152.4 0.1 2.2e-44 151.9 0.1 1.2 1 0 0 1 1 1 1 UreD urease accessory protein Abhydrolase_9_N PF15420.6 CEH16947.1 - 0.081 12.9 10.8 0.26 11.3 4.2 2.4 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Tmemb_55A PF09788.9 CEH16947.1 - 4.4 6.3 5.2 11 5.0 1.5 2.2 2 0 0 2 2 2 0 Transmembrane protein 55A MARVEL PF01284.23 CEH16949.1 - 0.00083 19.4 9.5 0.0017 18.4 9.1 1.6 1 1 0 1 1 1 1 Membrane-associating domain Ste5 PF11610.8 CEH16949.1 - 2.6 8.0 4.4 0.7 9.8 1.0 1.8 2 0 0 2 2 2 0 Scaffold protein Ste5, Fus3-binding region DUF3392 PF11872.8 CEH16949.1 - 7.6 6.8 11.0 1.6 9.0 6.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) RRM_1 PF00076.22 CEH16951.1 - 1.2e-22 79.5 0.0 1.7e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEH16951.1 - 0.0053 16.8 0.0 0.0086 16.2 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif IPP-2 PF04979.14 CEH16953.1 - 1e-17 65.1 8.2 1.3e-15 58.3 8.2 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) HSP20 PF00011.21 CEH16954.1 - 0.2 11.8 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 Hsp20/alpha crystallin family DnaJ_C PF01556.18 CEH16957.1 - 2e-33 115.5 0.0 3.7e-33 114.7 0.0 1.4 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.31 CEH16957.1 - 7.5e-23 80.4 1.7 1.3e-22 79.7 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEH16957.1 - 1.5e-13 50.9 16.3 2.7e-13 50.0 16.3 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 CEH16957.1 - 0.00071 19.6 6.9 0.24 11.4 1.1 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 CEH16957.1 - 0.31 11.0 11.4 1.1 9.2 2.7 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 CEH16957.1 - 1.1 9.4 7.4 3.1 7.9 7.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon NinF PF05810.12 CEH16957.1 - 9.4 6.2 9.5 1.3 8.9 1.8 2.5 2 1 1 3 3 3 0 NinF protein DPBB_1 PF03330.18 CEH16960.1 - 4e-09 36.6 0.0 5.9e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEH16960.1 - 0.0032 17.3 0.3 0.0067 16.3 0.2 1.4 1 1 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 CEH16960.1 - 0.13 12.4 0.1 0.4 10.8 0.1 1.7 1 1 1 2 2 2 0 Cerato-platanin Ribosomal_L37 PF08561.10 CEH16961.1 - 1.1e-26 93.7 0.2 2e-26 92.9 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 YtpI PF14007.6 CEH16962.1 - 5 7.3 7.2 0.9 9.7 2.9 2.0 2 0 0 2 2 2 0 YtpI-like protein AdoHcyase PF05221.17 CEH16963.1 - 1.3e-129 431.6 0.0 1.4e-75 254.2 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CEH16963.1 - 9.5e-85 282.6 2.5 1.6e-84 281.9 2.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CEH16963.1 - 5.8e-08 32.3 0.1 1.2e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CEH16963.1 - 0.00026 20.6 0.2 0.00042 19.9 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CEH16963.1 - 0.0034 17.6 0.0 0.0093 16.2 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Oxysterol_BP PF01237.18 CEH16964.1 - 1e-42 146.3 1.0 5.1e-25 88.1 2.3 4.0 2 1 0 2 2 2 2 Oxysterol-binding protein DUF3869 PF12985.7 CEH16964.1 - 0.011 16.1 0.1 0.061 13.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3869) La PF05383.17 CEH16966.1 - 8.3e-19 67.4 0.0 1.3e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 La domain SHMT PF00464.19 CEH16967.1 - 3.6e-171 569.2 0.0 4.3e-171 568.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CEH16967.1 - 6.9e-05 22.3 0.0 0.00024 20.5 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Macro PF01661.21 CEH16967.1 - 0.023 14.7 0.2 0.079 13.0 0.0 1.9 2 0 0 2 2 2 0 Macro domain Band_7 PF01145.25 CEH16968.1 - 1.7e-21 77.0 0.7 1.7e-21 77.0 0.7 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Lactonase PF10282.9 CEH16969.1 - 2.6e-63 214.4 0.0 3.4e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 CEH16969.1 - 0.00083 18.0 0.0 0.038 12.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 CEH16969.1 - 0.09 12.7 2.9 3.3 7.8 0.1 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat zf-C2H2 PF00096.26 CEH16970.1 - 0.0022 18.4 15.1 0.28 11.7 4.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEH16970.1 - 0.1 13.5 13.2 0.86 10.6 1.9 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger CHORD PF04968.12 CEH16970.1 - 7 7.5 8.9 20 6.0 0.9 2.9 1 1 1 2 2 2 0 CHORD Peptidase_M16 PF00675.20 CEH16972.1 - 9.1e-21 74.4 0.2 1.8e-20 73.4 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CEH16972.1 - 5.2e-12 46.2 0.0 1.1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Spore_IV_A PF09547.10 CEH16972.1 - 0.22 10.4 0.0 0.34 9.8 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Ribosomal_L11_N PF03946.14 CEH16973.1 - 2.1e-22 78.7 0.1 3.6e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CEH16973.1 - 2e-16 60.3 0.5 3.6e-16 59.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_S26e PF01283.19 CEH16974.1 - 1.8e-55 185.9 7.6 2.2e-55 185.7 7.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e CYTL1 PF15153.6 CEH16974.1 - 0.12 12.3 2.7 0.19 11.7 0.5 1.9 1 1 1 2 2 2 0 Cytokine-like protein 1 RabGAP-TBC PF00566.18 CEH16976.1 - 3.5e-44 151.0 0.0 8.7e-44 149.7 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FAD_binding_7 PF03441.14 CEH16977.1 - 6.9e-48 162.8 0.2 1e-47 162.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CEH16977.1 - 1.2e-22 80.7 0.0 2.7e-22 79.5 0.0 1.5 1 1 0 1 1 1 1 DNA photolyase MTS PF05175.14 CEH16978.1 - 0.00032 20.3 0.1 0.005 16.4 0.1 2.5 1 1 1 2 2 2 1 Methyltransferase small domain DEAD PF00270.29 CEH16979.1 - 2e-36 125.4 0.2 4.2e-36 124.3 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH16979.1 - 2.2e-25 89.1 0.1 4.7e-24 84.9 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH16979.1 - 1.6e-07 31.5 0.0 3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CEH16979.1 - 0.013 14.8 0.0 0.039 13.3 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Syntaphilin PF15290.6 CEH16979.1 - 0.029 14.0 0.4 0.051 13.2 0.4 1.3 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp HlyIII PF03006.20 CEH16980.1 - 1.2e-57 195.3 22.8 5.7e-57 193.0 22.8 1.8 1 1 0 1 1 1 1 Haemolysin-III related zf-RING_UBOX PF13445.6 CEH16983.1 - 1.9e-09 37.4 1.1 3.8e-09 36.4 1.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEH16983.1 - 1.3e-08 34.6 1.2 2.2e-08 33.8 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEH16983.1 - 5.5e-08 32.5 0.3 1.2e-07 31.5 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEH16983.1 - 5e-05 23.6 5.4 8.6e-05 22.8 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CEH16983.1 - 6.3e-05 23.0 1.2 0.00012 22.2 1.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CEH16983.1 - 0.00033 20.6 2.9 0.00062 19.7 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEH16983.1 - 0.001 18.9 3.9 0.0016 18.2 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEH16983.1 - 0.0013 18.5 1.9 0.0029 17.4 1.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CEH16983.1 - 0.0075 16.1 1.9 0.013 15.3 1.9 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 CEH16983.1 - 0.62 9.9 5.0 1.7 8.5 5.0 1.8 1 1 0 1 1 1 0 RING-like zinc finger WD40 PF00400.32 CEH16984.1 - 4e-44 147.7 16.2 5.4e-08 33.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH16984.1 - 5.2e-11 42.7 0.5 0.037 14.3 0.0 5.0 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEH16984.1 - 6.1e-05 21.9 4.3 0.025 13.2 0.1 3.9 2 1 0 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 CEH16984.1 - 0.0037 17.2 2.7 8.9 6.4 0.1 5.3 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat JUPITER PF17054.5 CEH16984.1 - 0.029 13.8 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Cytochrom_D1 PF02239.16 CEH16984.1 - 0.029 12.9 0.1 0.53 8.7 0.1 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain La PF05383.17 CEH16985.1 - 2.9e-18 65.7 0.0 6.6e-18 64.5 0.0 1.6 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 CEH16985.1 - 2.5e-07 30.4 0.4 4.2e-07 29.7 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 CEH16986.1 - 1.5e-37 128.3 0.1 1.8e-37 128.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NOA36 PF06524.12 CEH16986.1 - 9 5.5 8.0 12 5.1 8.0 1.1 1 0 0 1 1 1 0 NOA36 protein adh_short_C2 PF13561.6 CEH16987.1 - 6e-38 130.7 0.1 8.5e-38 130.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH16987.1 - 2.1e-35 122.0 0.3 3.8e-35 121.1 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH16987.1 - 0.0001 22.2 0.2 0.00019 21.4 0.0 1.6 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 CEH16987.1 - 0.0053 16.1 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 CEH16987.1 - 0.077 13.0 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CEH16987.1 - 0.16 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Tetraspanin PF00335.20 CEH16988.1 - 1e-06 28.7 9.2 1.9e-06 27.8 9.2 1.5 1 0 0 1 1 1 1 Tetraspanin family CcmD PF04995.14 CEH16988.1 - 0.52 10.4 4.2 2.9 8.0 4.2 2.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FliS PF02561.14 CEH16992.1 - 0.12 12.6 0.4 0.43 10.8 0.2 2.0 2 1 0 2 2 2 0 Flagellar protein FliS Transglut_core3 PF13471.6 CEH16994.1 - 0.03 14.2 0.3 0.061 13.2 0.3 1.9 1 1 0 1 1 1 0 Transglutaminase-like superfamily DUF3177 PF11375.8 CEH16997.1 - 0.034 13.9 1.4 0.075 12.8 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) OppC_N PF12911.7 CEH16997.1 - 0.87 9.6 3.3 7.3 6.7 0.1 3.3 2 1 1 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Lipase_GDSL_2 PF13472.6 CEH17000.1 - 1.1e-05 25.9 1.0 0.00013 22.5 1.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CEH17000.1 - 2e-05 24.7 0.0 2.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase EZH2_N PF18601.1 CEH17000.1 - 0.2 12.0 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 EZH2 N-terminal domain PIG-S PF10510.9 CEH17002.1 - 9.1e-98 328.3 2.5 1.2e-97 327.9 2.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Trs65 PF12735.7 CEH17002.1 - 0.0046 16.4 1.8 0.024 14.1 0.1 2.1 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 FAD-oxidase_C PF02913.19 CEH17003.1 - 9.1e-60 202.4 0.0 1.8e-59 201.4 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CEH17003.1 - 3.3e-31 107.9 0.2 5.7e-31 107.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain SUIM_assoc PF16619.5 CEH17003.1 - 3.1 7.9 11.7 7.2 6.8 11.7 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FLILHELTA PF10306.9 CEH17008.1 - 7.3e-17 61.6 0.0 2.4e-16 59.9 0.0 2.0 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA tRNA-synt_2b PF00587.25 CEH17008.1 - 1.8e-16 60.6 0.0 3.1e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Spc7 PF08317.11 CEH17008.1 - 0.099 11.5 5.5 0.15 10.9 5.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 CEH17008.1 - 9.7 6.1 9.1 4.1 7.3 5.1 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF4601 PF15373.6 CEH17013.1 - 0.089 11.7 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) AAA PF00004.29 CEH17014.1 - 4.2e-83 276.4 0.0 3.1e-41 140.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEH17014.1 - 3.3e-25 87.6 1.6 1.6e-12 47.0 0.4 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CEH17014.1 - 1.2e-11 45.3 0.4 7.9e-05 23.1 0.0 4.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CEH17014.1 - 6.8e-10 39.1 0.0 9.5e-05 22.4 0.0 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEH17014.1 - 1.6e-09 37.7 0.0 0.00028 20.7 0.0 3.2 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CEH17014.1 - 1.5e-08 35.0 0.0 0.0017 18.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CEH17014.1 - 2.5e-08 33.9 0.0 3.6e-05 23.6 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein TIP49 PF06068.13 CEH17014.1 - 7.9e-08 31.9 0.1 0.0072 15.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 CEH17014.1 - 3.2e-07 30.6 0.0 0.0022 18.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEH17014.1 - 8.2e-06 26.1 3.6 0.07 13.4 0.2 4.4 3 2 1 4 4 3 1 AAA domain AAA_25 PF13481.6 CEH17014.1 - 1.3e-05 24.9 0.3 0.27 10.8 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 CEH17014.1 - 7.9e-05 23.2 0.0 0.015 15.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CEH17014.1 - 0.00016 21.1 1.2 0.34 10.3 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CEH17014.1 - 0.00023 21.2 0.0 0.055 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CEH17014.1 - 0.00035 20.9 0.0 0.58 10.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 CEH17014.1 - 0.00079 19.7 0.1 1.4 9.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CEH17014.1 - 0.00085 18.7 0.0 0.17 11.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 CEH17014.1 - 0.00088 18.8 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 CEH17014.1 - 0.0012 18.7 0.0 0.52 10.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CEH17014.1 - 0.006 16.5 0.7 0.16 11.9 0.0 2.8 2 2 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 CEH17014.1 - 0.0061 16.6 0.0 0.58 10.2 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CEH17014.1 - 0.0062 16.3 0.0 0.073 12.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CEH17014.1 - 0.01 15.7 0.0 0.66 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CEH17014.1 - 0.022 15.2 0.0 3.9 7.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CEH17014.1 - 0.022 14.5 0.0 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain ATPase_2 PF01637.18 CEH17014.1 - 0.034 14.0 0.0 8.1 6.3 0.0 3.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 CEH17014.1 - 0.041 13.0 0.0 0.93 8.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 CEH17014.1 - 0.041 13.0 0.0 0.71 9.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) PhoH PF02562.16 CEH17014.1 - 0.063 12.7 0.1 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein IPT PF01745.16 CEH17014.1 - 0.07 12.5 0.1 2.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase ABC_tran PF00005.27 CEH17014.1 - 0.072 13.6 0.0 2.3 8.7 0.0 2.8 2 1 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.6 CEH17014.1 - 0.072 13.2 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Vps4_C PF09336.10 CEH17014.1 - 0.077 13.0 0.1 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain ATPase PF06745.13 CEH17014.1 - 0.088 12.1 0.0 5.2 6.3 0.0 2.9 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 CEH17014.1 - 0.11 12.5 0.4 6.1 6.7 0.0 3.7 4 2 2 6 6 4 0 NACHT domain SKI PF01202.22 CEH17014.1 - 2.5 8.2 4.1 44 4.1 0.3 3.2 3 0 0 3 3 3 0 Shikimate kinase RRM_1 PF00076.22 CEH17015.1 - 1.7e-17 63.0 0.1 1.8e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEH17015.1 - 0.00032 20.3 0.0 0.01 15.4 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CEH17015.1 - 0.044 13.9 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 DEAD PF00270.29 CEH17016.1 - 1.3e-15 57.6 0.0 2.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH17016.1 - 4.2e-06 27.1 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DNA_pol_B PF00136.21 CEH17017.1 - 7e-89 298.6 0.0 9.9e-89 298.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CEH17017.1 - 8.8e-25 87.6 0.0 3.6e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 CEH17017.1 - 0.093 11.6 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral MAP65_ASE1 PF03999.12 CEH17017.1 - 2.6 6.6 7.4 5.2 5.6 7.4 1.5 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) zf-C4pol PF14260.6 CEH17018.1 - 3.2e-09 37.1 9.6 8.5e-08 32.6 9.6 2.1 1 1 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF2797 PF10977.8 CEH17018.1 - 0.18 11.7 7.2 0.35 10.7 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2797) RecR PF02132.15 CEH17018.1 - 0.18 11.4 11.0 0.18 11.4 3.9 2.3 2 0 0 2 2 2 0 RecR protein GNAT_acetyltr_2 PF13718.6 CEH17021.1 - 2.5e-88 295.3 0.5 1.2e-87 293.1 0.0 2.2 2 1 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 CEH17021.1 - 2.4e-60 203.4 0.0 5.3e-60 202.3 0.0 1.6 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 CEH17021.1 - 7e-47 160.1 10.8 2.2e-29 102.9 0.1 2.5 2 0 0 2 2 2 2 Possible tRNA binding domain DUF1726 PF08351.11 CEH17021.1 - 5.9e-29 99.8 0.0 1.7e-28 98.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_7 PF13508.7 CEH17021.1 - 0.014 15.8 0.0 0.049 14.1 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEH17021.1 - 0.023 14.9 0.0 0.084 13.1 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 CEH17021.1 - 0.081 12.9 0.2 19 5.3 0.0 2.7 2 0 0 2 2 2 0 FR47-like protein DnaJ_C PF01556.18 CEH17022.1 - 2.1e-31 109.0 0.0 2.8e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEH17022.1 - 3.7e-24 84.6 0.1 5.5e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEH17022.1 - 1.9e-11 44.1 19.2 3.1e-11 43.5 19.2 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CEH17022.1 - 0.00035 20.5 12.3 0.1 12.6 1.6 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CEH17022.1 - 0.22 11.6 6.1 2.9 7.9 1.4 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CEH17022.1 - 3.2 7.8 10.0 6.9 6.8 1.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon SKN1 PF03935.15 CEH17024.1 - 8.6e-187 621.5 1.4 9.9e-187 621.3 1.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Asp PF00026.23 CEH17025.1 - 5.5e-114 380.8 0.0 6.3e-114 380.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEH17025.1 - 4.3e-16 59.7 1.7 6.9e-14 52.5 1.8 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEH17025.1 - 4.4e-05 23.3 0.0 0.001 18.8 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CEH17025.1 - 0.00027 21.5 0.0 0.087 13.5 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CEH17025.1 - 0.0013 19.2 0.0 0.43 11.2 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Pkinase PF00069.25 CEH17026.1 - 6.2e-74 248.7 0.0 8.4e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17026.1 - 6.9e-36 123.8 0.0 1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 CEH17026.1 - 6.5e-18 65.3 0.0 8.6e-16 58.4 0.0 2.6 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 CEH17026.1 - 3.1e-08 33.3 0.0 4.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.11 CEH17026.1 - 1.4e-06 28.3 0.5 3.2e-06 27.1 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.22 CEH17026.1 - 0.0029 17.2 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CEH17026.1 - 0.019 13.9 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pap_E4 PF02711.14 CEH17026.1 - 0.066 14.2 0.6 0.28 12.2 0.6 2.1 1 0 0 1 1 1 0 E4 protein YukC PF10140.9 CEH17026.1 - 0.41 9.4 1.2 0.46 9.3 0.1 1.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Ku PF02735.16 CEH17029.1 - 1.6e-35 122.6 0.0 2.5e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CEH17029.1 - 2.3e-10 40.6 0.0 1.6e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CEH17029.1 - 4.2e-10 40.2 0.0 1.2e-09 38.7 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 CEH17029.1 - 1.3e-08 34.4 0.0 2.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain TPR_14 PF13428.6 CEH17030.1 - 2.5e-07 30.9 39.5 0.0059 17.3 0.6 9.9 6 3 4 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEH17030.1 - 7.5e-07 28.7 4.0 0.075 12.9 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEH17030.1 - 0.0003 21.2 29.5 0.0029 18.1 1.7 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEH17030.1 - 0.00057 20.1 0.8 26 5.5 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEH17030.1 - 0.0066 16.6 8.1 0.12 12.6 0.0 5.4 7 0 0 7 7 7 1 Tetratricopeptide repeat ChAPs PF09295.10 CEH17030.1 - 0.024 13.7 0.8 0.06 12.3 0.1 1.9 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 CEH17030.1 - 0.034 14.3 19.8 0.072 13.2 0.1 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEH17030.1 - 0.11 12.6 12.7 7.1 6.9 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.25 CEH17031.1 - 2.7e-69 233.5 0.0 3.7e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17031.1 - 2.1e-48 164.9 0.0 3.2e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 CEH17031.1 - 6e-19 68.2 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 CEH17031.1 - 1.9e-11 43.9 0.0 3.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEH17031.1 - 3.9e-10 40.0 0.0 7.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 CEH17031.1 - 4.5e-05 22.9 0.0 0.0004 19.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEH17031.1 - 0.013 14.3 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SAM_4 PF18017.1 CEH17031.1 - 0.02 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AXIN1_TNKS_BD PF16646.5 CEH17031.1 - 0.14 13.1 8.4 3.8 8.5 1.7 3.8 2 0 0 2 2 2 0 Axin-1 tankyrase binding domain RA PF00788.23 CEH17031.1 - 0.16 12.6 0.0 0.32 11.7 0.0 1.4 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain PPP4R2 PF09184.11 CEH17031.1 - 0.24 11.0 8.5 0.46 10.0 8.5 1.5 1 0 0 1 1 1 0 PPP4R2 DnaJ PF00226.31 CEH17033.1 - 2.8e-17 62.6 1.0 4.7e-17 61.9 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain Bacteriocin_IIc PF10439.9 CEH17033.1 - 0.0055 16.8 6.9 0.01 15.9 0.9 2.4 2 0 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide PRY PF13765.6 CEH17033.1 - 0.096 12.3 0.3 5 6.8 0.1 2.4 2 0 0 2 2 2 0 SPRY-associated domain Gly-zipper_YMGG PF13441.6 CEH17033.1 - 1.4 8.7 14.3 7.3 6.4 7.7 2.6 2 1 0 2 2 2 0 YMGG-like Gly-zipper Methyltransf_28 PF02636.17 CEH17034.1 - 3.6e-61 207.1 0.0 4.8e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Mito_carr PF00153.27 CEH17035.1 - 2.1e-72 239.1 0.3 1.8e-24 85.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EVE PF01878.18 CEH17037.1 - 6.5e-22 78.1 0.0 1e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 EVE domain PDH PF02153.17 CEH17038.1 - 1.8e-13 50.1 0.0 2.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 CEH17038.1 - 4.9e-08 33.4 0.0 1.5e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CEH17038.1 - 2.4e-06 27.8 0.0 4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CEH17038.1 - 0.00028 20.9 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CEH17038.1 - 0.00055 19.3 0.0 0.00091 18.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CEH17038.1 - 0.0049 16.5 0.0 0.0094 15.6 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CEH17038.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 CEH17038.1 - 0.029 14.2 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.18 CEH17038.1 - 0.09 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Tmemb_cc2 PF10267.9 CEH17039.1 - 0.0043 16.3 0.2 0.0049 16.1 0.2 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Pex14_N PF04695.13 CEH17039.1 - 6.7 7.3 12.5 4.1 8.0 2.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HEAT PF02985.22 CEH17040.1 - 1.7e-36 121.1 20.4 0.016 15.4 0.1 13.9 15 0 0 15 15 15 9 HEAT repeat HEAT_2 PF13646.6 CEH17040.1 - 2.1e-33 114.5 12.3 6.7e-11 42.4 0.0 7.6 3 3 5 8 8 8 7 HEAT repeats HEAT_EZ PF13513.6 CEH17040.1 - 2.1e-13 50.4 15.2 0.23 12.0 0.1 8.4 6 1 2 8 8 8 5 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CEH17040.1 - 8.7e-12 45.5 0.5 0.025 15.1 0.0 6.3 3 2 4 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CEH17040.1 - 3.6e-10 40.1 6.0 0.0046 17.0 0.1 5.3 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CEH17040.1 - 0.00016 21.3 0.5 0.3 10.6 0.0 4.1 2 2 2 4 4 4 2 CLASP N terminal Adaptin_N PF01602.20 CEH17040.1 - 0.00061 18.5 6.6 0.14 10.6 0.2 4.3 4 1 0 4 4 4 2 Adaptin N terminal region Arm PF00514.23 CEH17040.1 - 0.0016 18.4 1.9 18 5.6 0.0 5.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 CEH17040.1 - 0.077 13.2 7.1 8.7 6.6 0.1 4.2 4 2 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 CEH17040.1 - 0.1 13.3 0.2 12 7.0 0.0 4.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF2470 PF10615.9 CEH17041.1 - 7.5e-08 32.9 0.0 2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 CEH17041.1 - 8.9e-05 22.7 0.1 0.00016 21.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Syja_N PF02383.18 CEH17042.1 - 8.8e-76 255.3 0.0 1.5e-75 254.5 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Phage_tail_T PF06223.12 CEH17042.1 - 0.049 14.2 0.1 0.3 11.6 0.0 2.4 3 0 0 3 3 3 0 Minor tail protein T MAD PF05557.13 CEH17043.1 - 1.2e-30 106.5 65.3 1.3e-30 106.4 14.1 2.0 2 0 0 2 2 2 2 Mitotic checkpoint protein ATG16 PF08614.11 CEH17043.1 - 0.00011 22.5 9.3 0.00011 22.5 9.3 6.3 2 2 4 6 6 6 1 Autophagy protein 16 (ATG16) TLE_N PF03920.15 CEH17043.1 - 3.4 7.8 17.1 0.082 13.0 1.2 4.4 3 2 1 4 4 4 0 Groucho/TLE N-terminal Q-rich domain Ncstrn_small PF18266.1 CEH17044.1 - 0.035 14.1 0.1 0.056 13.4 0.0 1.4 2 0 0 2 2 2 0 Nicastrin small lobe LPMO_10 PF03067.15 CEH17044.1 - 0.067 13.8 0.0 0.081 13.6 0.0 1.1 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading CotE PF10628.9 CEH17045.1 - 0.064 12.9 0.5 0.13 11.9 0.5 1.5 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) FTR1 PF03239.14 CEH17046.1 - 2e-49 168.5 5.3 4.9e-31 108.0 2.9 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family CbtA PF09490.10 CEH17046.1 - 0.0017 18.1 0.3 0.0017 18.1 0.3 2.5 3 1 0 3 3 3 1 Probable cobalt transporter subunit (CbtA) Herpes_glycop PF01528.16 CEH17046.1 - 0.0039 16.1 0.0 0.0089 14.9 0.0 1.6 1 0 0 1 1 1 1 Herpesvirus glycoprotein M OPT PF03169.15 CEH17047.1 - 1.9e-114 383.6 1.9 5.3e-114 382.1 1.9 1.6 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF4328 PF14219.6 CEH17047.1 - 0.25 10.9 6.5 0.23 11.0 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) Cu-oxidase_2 PF07731.14 CEH17048.1 - 6.3e-36 123.1 4.6 4.1e-35 120.5 2.8 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 CEH17048.1 - 2.2e-21 76.7 0.2 2.6e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase HVSL PF09749.9 CEH17048.1 - 0.04 13.4 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein Mre11_DNA_bind PF04152.14 CEH17049.1 - 3.8e-46 157.5 0.7 7.5e-46 156.5 0.7 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CEH17049.1 - 2e-11 44.8 1.2 4.3e-11 43.7 1.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEH17049.1 - 3.1e-05 24.2 0.3 0.0014 18.8 0.3 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIE-A_C PF11521.8 CEH17049.1 - 0.41 11.0 9.9 10 6.5 1.1 3.9 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Arm PF00514.23 CEH17050.1 - 5.9e-94 305.6 13.0 6.1e-13 48.3 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CEH17050.1 - 1.2e-21 76.0 1.1 2.3e-21 75.1 1.1 1.5 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 CEH17050.1 - 2.5e-19 69.4 3.2 5.9e-06 26.7 0.1 6.7 3 2 3 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.6 CEH17050.1 - 1.3e-17 64.0 0.3 4e-06 27.1 0.0 5.3 2 1 4 6 6 6 6 HEAT repeats HEAT PF02985.22 CEH17050.1 - 5.1e-14 51.2 3.0 0.0007 19.6 0.0 7.4 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.20 CEH17050.1 - 3e-06 26.1 0.0 6.7e-05 21.6 0.0 2.6 1 1 2 3 3 3 1 Adaptin N terminal region Arm_2 PF04826.13 CEH17050.1 - 8.2e-06 25.5 0.0 0.14 11.6 0.0 4.0 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 CEH17050.1 - 7.9e-05 22.7 0.0 0.094 12.8 0.0 4.0 4 1 1 5 5 5 1 V-ATPase subunit H RICTOR_V PF14668.6 CEH17050.1 - 0.00082 19.6 6.3 0.088 13.1 0.1 4.4 3 2 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 CEH17050.1 - 0.0023 18.4 0.9 0.4 11.5 0.1 4.5 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 CEH17050.1 - 0.031 14.3 0.0 6.1 6.9 0.0 3.1 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain GTP_cyclohydro2 PF00925.20 CEH17051.1 - 5.4e-64 214.7 0.2 5.5e-63 211.4 0.2 2.1 1 1 0 1 1 1 1 GTP cyclohydrolase II Herpes_DNAp_acc PF04929.12 CEH17051.1 - 4.5 6.1 9.5 12 4.7 9.5 1.7 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Talin_middle PF09141.10 CEH17052.1 - 0.0081 16.2 0.8 0.014 15.4 0.8 1.3 1 0 0 1 1 1 1 Talin, middle domain FlxA PF14282.6 CEH17052.1 - 0.073 13.1 12.4 0.12 12.4 12.4 1.3 1 0 0 1 1 1 0 FlxA-like protein Atg14 PF10186.9 CEH17052.1 - 0.2 10.7 6.8 0.26 10.3 6.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HALZ PF02183.18 CEH17052.1 - 0.5 10.6 4.4 0.86 9.9 4.4 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3450 PF11932.8 CEH17052.1 - 0.5 9.6 7.6 0.78 9.0 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) LCD1 PF09798.9 CEH17052.1 - 8.1 4.8 7.5 11 4.4 7.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Pkinase PF00069.25 CEH17056.1 - 1.4e-61 208.2 0.0 1.7e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17056.1 - 4e-46 157.4 0.1 5.2e-46 157.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CEH17056.1 - 4.7e-05 23.1 0.1 0.0001 22.0 0.1 1.5 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.6 CEH17056.1 - 0.0003 20.2 0.0 0.0081 15.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CEH17056.1 - 0.0046 16.1 0.2 0.0082 15.2 0.2 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 CEH17056.1 - 0.0095 14.7 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CEH17056.1 - 0.16 11.5 0.2 0.23 10.9 0.2 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 CEH17056.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 CEH17056.1 - 0.21 11.2 0.1 0.32 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 RabGAP-TBC PF00566.18 CEH17058.1 - 5.8e-33 114.4 2.1 5.5e-30 104.6 0.2 3.2 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Cep57_MT_bd PF06657.13 CEH17059.1 - 1.5e-07 31.8 0.8 1.5e-07 31.8 0.8 1.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Syntaxin PF00804.25 CEH17059.1 - 0.48 10.1 4.6 0.76 9.4 2.1 2.2 1 1 1 2 2 2 0 Syntaxin rve_3 PF13683.6 CEH17061.1 - 0.079 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF1708 PF08101.11 CEH17062.1 - 5.6e-19 68.6 0.0 2.6e-16 59.8 0.0 2.6 2 2 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 CEH17062.1 - 0.0016 18.3 0.0 0.0061 16.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain DENN PF02141.21 CEH17063.1 - 1.1e-20 74.4 0.0 1.7e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Spc7 PF08317.11 CEH17063.1 - 0.28 10.0 14.7 0.028 13.3 9.9 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein FlxA PF14282.6 CEH17063.1 - 0.45 10.5 13.3 6.4 6.8 0.4 3.2 2 0 0 2 2 2 0 FlxA-like protein GAS PF13851.6 CEH17063.1 - 1 8.7 10.7 0.55 9.6 7.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SOGA PF11365.8 CEH17063.1 - 1.2 10.4 8.3 8.1 7.7 8.0 2.8 1 1 0 1 1 1 0 Protein SOGA YTH PF04146.15 CEH17064.1 - 2.5e-55 186.9 0.0 9.9e-55 185.0 0.0 2.0 2 0 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 CEH17064.1 - 0.0053 16.5 0.4 1 9.2 0.1 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4329 PF14220.6 CEH17064.1 - 0.029 14.4 0.1 0.097 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) Mcm10 PF09332.11 CEH17064.1 - 0.3 10.5 3.4 0.6 9.5 3.4 1.4 1 0 0 1 1 1 0 Mcm10 replication factor Lysine_decarbox PF03641.14 CEH17065.1 - 1.2e-30 106.3 0.0 3.9e-30 104.6 0.0 1.8 1 1 0 1 1 1 1 Possible lysine decarboxylase ABC_tran PF00005.27 CEH17065.1 - 3.4e-14 53.5 0.3 2.1e-07 31.5 0.0 2.8 2 1 1 3 3 3 2 ABC transporter LDcluster4 PF18306.1 CEH17065.1 - 5.9e-12 45.5 0.3 3.8e-08 33.1 0.2 2.3 2 0 0 2 2 2 2 SLOG cluster4 family AAA_21 PF13304.6 CEH17065.1 - 3.5e-10 40.2 3.0 8.7e-05 22.5 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CEH17065.1 - 0.00029 21.3 0.9 0.00088 19.7 0.1 2.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 CEH17065.1 - 0.00043 20.6 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CEH17065.1 - 0.0015 18.2 0.1 0.0037 17.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEH17065.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 CEH17065.1 - 0.021 14.4 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CEH17065.1 - 0.052 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CEH17065.1 - 0.094 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CEH17065.1 - 0.096 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 CEH17065.1 - 0.11 12.7 0.1 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CEH17065.1 - 0.26 11.0 0.1 0.38 10.4 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain ADH_zinc_N PF00107.26 CEH17066.1 - 1.3e-11 44.6 1.4 4.8e-11 42.8 0.4 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEH17066.1 - 9.5e-10 39.6 0.1 6.1e-09 37.0 0.0 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH17066.1 - 7.2e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF922 PF06037.11 CEH17066.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) NAD_binding_10 PF13460.6 CEH17067.1 - 4.5e-26 91.9 0.0 6.6e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CEH17067.1 - 0.0017 17.6 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 CEH17067.1 - 0.0068 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family SAND PF01342.21 CEH17067.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 SAND domain Phage_tail_APC PF16778.5 CEH17067.1 - 0.087 12.7 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Phage tail assembly chaperone protein DeoC PF01791.9 CEH17068.1 - 1.1e-06 28.5 1.1 1.5e-06 28.0 1.1 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 CEH17068.1 - 0.0013 18.2 0.3 0.004 16.6 0.0 1.9 2 1 1 3 3 3 1 Histidine biosynthesis protein Ribosomal_L13e PF01294.18 CEH17069.1 - 1.5e-64 217.1 5.0 2.3e-64 216.5 5.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S10 PF00338.22 CEH17070.1 - 3.2e-19 69.0 0.0 7.1e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FA_hydroxylase PF04116.13 CEH17072.1 - 7.1e-21 74.9 12.0 7.1e-21 74.9 12.0 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily ABC_membrane PF00664.23 CEH17074.1 - 1.2e-42 146.5 8.2 9.6e-20 71.3 1.0 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 CEH17074.1 - 3.8e-33 114.9 0.0 2.6e-25 89.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEH17074.1 - 3.5e-10 39.7 0.0 0.0037 16.7 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 CEH17074.1 - 0.0046 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 CEH17074.1 - 0.0072 16.6 0.0 0.52 10.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 CEH17074.1 - 0.03 14.1 0.1 7.4 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEH17074.1 - 0.055 13.2 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CEH17074.1 - 0.11 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 CEH17074.1 - 0.14 12.7 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CEH17074.1 - 0.15 11.2 0.0 0.56 9.3 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain NUDIX_2 PF13869.6 CEH17075.1 - 5.7e-78 260.8 0.0 6.5e-78 260.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Ammonium_transp PF00909.21 CEH17076.1 - 1.1e-108 363.5 27.9 1.3e-108 363.3 27.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 CEH17076.1 - 0.029 14.4 2.5 0.029 14.4 2.5 2.4 2 0 0 2 2 2 0 Bacteriophage P21 holin S Pil1 PF13805.6 CEH17078.1 - 8.5e-19 68.1 0.1 1.5e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 RhoGEF PF00621.20 CEH17078.1 - 0.15 12.3 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 RhoGEF domain LOR PF04525.12 CEH17079.1 - 1.7e-20 73.4 0.0 2.1e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related Apt1 PF10351.9 CEH17080.1 - 0.017 14.0 7.8 0.02 13.8 7.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sec3_C PF09763.9 CEH17080.1 - 0.019 13.4 2.0 0.024 13.0 2.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 SPX PF03105.19 CEH17080.1 - 0.066 13.1 9.2 0.08 12.8 9.2 1.3 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 CEH17080.1 - 0.1 11.3 2.5 0.14 10.9 2.5 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CEH17080.1 - 0.47 9.1 9.6 0.59 8.8 9.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pol_alpha_B_N PF08418.10 CEH17080.1 - 0.69 9.8 13.8 1 9.3 13.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RR_TM4-6 PF06459.12 CEH17080.1 - 0.72 9.6 2.5 1.1 9.1 2.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Utp14 PF04615.13 CEH17080.1 - 0.85 8.1 7.5 1.1 7.7 7.5 1.1 1 0 0 1 1 1 0 Utp14 protein Miga PF10265.9 CEH17080.1 - 1.3 7.9 9.4 1.7 7.5 9.4 1.1 1 0 0 1 1 1 0 Mitoguardin NPR3 PF03666.13 CEH17080.1 - 6 5.5 7.9 7.6 5.2 7.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tmemb_cc2 PF10267.9 CEH17080.1 - 6.7 5.7 7.4 9.1 5.3 7.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Plasmodium_Vir PF05795.11 CEH17080.1 - 8 5.8 8.4 49 3.2 9.1 1.7 1 1 1 2 2 2 0 Plasmodium vivax Vir protein SOBP PF15279.6 CEH17080.1 - 9.7 6.7 9.6 16 6.0 9.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein UQ_con PF00179.26 CEH17081.1 - 1.8e-18 66.5 0.0 3.1e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Fungal_trans PF04082.18 CEH17082.1 - 5.1e-17 61.8 0.0 9.8e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH17082.1 - 3.4e-07 30.3 11.1 6.2e-07 29.4 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COPIIcoated_ERV PF07970.12 CEH17083.1 - 1e-76 257.7 0.0 1.5e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CEH17083.1 - 2.1e-27 95.3 0.4 3.9e-27 94.4 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TPPK_C PF12555.8 CEH17083.1 - 0.064 13.3 2.0 0.16 12.0 2.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal TPR_1 PF00515.28 CEH17084.1 - 5e-11 41.9 1.8 0.00028 20.6 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEH17084.1 - 3e-10 39.4 3.3 0.0059 16.6 0.2 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 CEH17084.1 - 3.2e-09 36.8 0.3 1.1e-08 35.0 0.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEH17084.1 - 0.0004 21.0 5.9 0.0059 17.2 0.3 3.0 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEH17084.1 - 0.00084 19.8 4.6 0.047 14.2 0.4 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEH17084.1 - 0.0024 18.1 5.3 1.5 9.2 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEH17084.1 - 0.004 17.4 1.0 0.42 11.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEH17084.1 - 0.033 13.9 2.3 1.1 9.0 0.0 3.6 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.6 CEH17084.1 - 0.035 14.1 0.5 14 5.9 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEH17084.1 - 0.047 14.5 7.7 7.7 7.6 0.1 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 CEH17084.1 - 0.14 12.0 0.7 0.3 10.9 0.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Aa_trans PF01490.18 CEH17088.1 - 5.9e-46 157.0 28.7 3e-38 131.6 19.9 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Lysyl_oxidase PF01186.17 CEH17091.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Lysyl oxidase gag_pre-integrs PF13976.6 CEH17091.1 - 0.02 14.8 0.5 0.049 13.5 0.5 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain Cation_efflux PF01545.21 CEH17093.1 - 2e-25 89.7 1.0 3.1e-25 89.1 1.0 1.3 1 0 0 1 1 1 1 Cation efflux family TFIIA PF03153.13 CEH17093.1 - 0.6 10.0 3.7 0.81 9.6 3.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ICL PF00463.21 CEH17094.1 - 9e-190 631.6 0.0 1e-189 631.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CEH17094.1 - 7.1e-10 38.7 0.0 1.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF2458 PF10454.9 CEH17094.1 - 0.12 12.1 0.2 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF3235 PF11574.8 CEH17094.1 - 0.66 10.9 2.2 6.9 7.6 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3235) Chitin_synth_2 PF03142.15 CEH17095.1 - 9.5e-236 783.5 0.4 1.4e-235 782.9 0.4 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CEH17095.1 - 1.7e-127 426.5 0.0 8.8e-116 387.8 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) DEK_C PF08766.11 CEH17095.1 - 8.5e-21 73.6 0.2 6.8e-13 48.3 0.2 3.6 3 0 0 3 3 3 2 DEK C terminal domain Cyt-b5 PF00173.28 CEH17095.1 - 4.2e-14 52.4 0.2 2.4e-10 40.4 0.0 3.2 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 CEH17095.1 - 1.3e-13 51.3 2.4 4.2e-13 49.7 2.4 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEH17095.1 - 2.6e-10 40.6 0.0 7.1e-09 35.9 0.0 2.8 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CEH17095.1 - 0.00052 19.9 0.0 0.21 11.4 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Aldedh PF00171.22 CEH17096.1 - 4.8e-148 493.5 0.0 5.5e-148 493.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Thx PF17070.5 CEH17096.1 - 0.0016 18.4 0.8 0.004 17.2 0.8 1.6 1 0 0 1 1 1 1 30S ribosomal protein Thx LuxC PF05893.14 CEH17096.1 - 0.0093 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) HAD PF12710.7 CEH17097.1 - 1.8e-06 28.5 0.1 4.6e-06 27.2 0.1 1.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DIL PF01843.19 CEH17097.1 - 0.11 12.7 0.5 1.9 8.8 0.0 2.2 2 0 0 2 2 2 0 DIL domain Pkinase PF00069.25 CEH17098.1 - 0.0017 17.7 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CEH17099.1 - 1.8e-14 53.7 0.0 2.2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17099.1 - 4.6e-06 26.1 0.0 9e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH17099.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Rad60-SLD PF11976.8 CEH17100.1 - 3.3e-16 58.9 0.1 4.3e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CEH17100.1 - 8.6e-08 31.8 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family TPR_1 PF00515.28 CEH17101.1 - 1.7e-31 106.7 7.8 1.1e-07 31.3 0.0 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 CEH17101.1 - 9.4e-30 100.3 13.2 3.3e-06 26.8 0.0 11.0 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 CEH17101.1 - 3.2e-20 72.5 26.3 4.2e-05 24.1 0.0 7.6 5 2 3 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 CEH17101.1 - 2.7e-18 65.3 14.0 0.0006 19.4 0.1 8.1 6 2 3 9 9 9 5 TPR repeat TPR_8 PF13181.6 CEH17101.1 - 5.6e-18 63.6 7.7 4.4e-05 23.4 0.0 8.9 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEH17101.1 - 1.8e-15 56.1 1.6 0.24 11.9 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEH17101.1 - 1.9e-13 50.5 22.7 0.026 14.8 0.1 8.0 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEH17101.1 - 2.2e-13 49.8 21.9 0.091 13.6 0.5 10.0 6 4 5 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 CEH17101.1 - 6.9e-13 48.9 22.3 5.5e-05 23.6 0.4 7.5 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 CEH17101.1 - 6.1e-10 38.4 10.7 1.6 9.0 0.1 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 CEH17101.1 - 1.7e-09 37.7 7.5 4e-05 23.7 0.1 5.5 3 1 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH17101.1 - 1.4e-08 34.8 5.5 0.019 15.1 0.0 5.2 3 1 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CEH17101.1 - 0.00061 19.6 12.3 4.9 7.2 0.3 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEH17101.1 - 0.00081 18.7 11.9 0.29 10.3 0.5 4.3 2 1 0 3 3 3 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 CEH17101.1 - 0.028 14.5 0.1 3.8 7.7 0.0 3.1 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region SHNi-TPR PF10516.9 CEH17101.1 - 0.076 12.5 3.8 5.2 6.6 0.0 3.6 3 0 0 3 3 3 0 SHNi-TPR VIT PF08487.10 CEH17101.1 - 1.7 8.9 6.2 0.31 11.3 0.3 2.7 4 0 0 4 4 2 0 Vault protein inter-alpha-trypsin domain DUF3712 PF12505.8 CEH17102.1 - 8.6e-97 320.0 23.6 4.4e-23 81.9 0.0 8.1 7 0 0 7 7 7 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 CEH17102.1 - 2.5e-07 31.2 8.6 0.71 10.5 0.1 6.9 6 0 0 6 6 6 3 Late embryogenesis abundant protein LRR_6 PF13516.6 CEH17104.1 - 1.2e-14 53.0 17.3 0.0018 18.2 0.2 6.4 6 0 0 6 6 6 5 Leucine Rich repeat GAT PF03127.14 CEH17104.1 - 1.5e-05 25.2 0.5 5e-05 23.5 0.5 1.9 1 0 0 1 1 1 1 GAT domain LRR_1 PF00560.33 CEH17104.1 - 8.9e-05 22.5 1.0 17 6.4 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 CEH17104.1 - 0.00028 21.2 8.2 0.043 14.3 0.4 3.8 1 1 2 4 4 4 2 Leucine Rich repeats (2 copies) DUF4551 PF15087.6 CEH17104.1 - 0.3 9.9 0.1 0.3 9.9 0.1 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF4551) FUSC PF04632.12 CEH17104.1 - 0.79 8.2 9.9 1.1 7.7 9.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LRR_8 PF13855.6 CEH17104.1 - 2.3 8.0 13.4 1.7 8.5 1.4 4.3 2 2 1 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 CEH17105.1 - 0.00042 20.1 0.8 0.48 10.6 0.3 2.8 2 0 0 2 2 2 2 Leucine Rich repeat LRR_1 PF00560.33 CEH17105.1 - 0.14 12.8 0.3 52 5.0 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 CEH17105.1 - 0.16 11.8 0.1 1.4 8.7 0.0 2.4 3 0 0 3 3 3 0 Leucine rich repeat Sugar_tr PF00083.24 CEH17106.1 - 1.5e-16 60.4 18.0 1.9e-14 53.4 4.9 2.6 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 CEH17106.1 - 4.8e-09 35.6 4.4 4.8e-09 35.6 4.4 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 CEH17106.1 - 0.0024 16.5 0.3 0.0024 16.5 0.3 2.3 2 1 0 2 2 2 2 MFS/sugar transport protein Peptidase_M16 PF00675.20 CEH17107.1 - 1.4e-09 38.1 0.0 2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF2052 PF09747.9 CEH17108.1 - 0.041 14.0 3.9 0.06 13.5 3.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PGM1_C PF18105.1 CEH17108.1 - 0.091 12.3 1.1 0.25 10.9 0.0 2.4 3 0 0 3 3 3 0 PGM1 C-terminal domain PCI PF01399.27 CEH17109.1 - 0.00021 21.7 0.0 0.0032 18.0 0.0 2.5 2 1 0 2 2 2 1 PCI domain TPR_19 PF14559.6 CEH17109.1 - 0.04 14.4 0.1 0.2 12.2 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 CEH17112.1 - 0.02 14.7 0.2 0.051 13.5 0.0 1.8 2 0 0 2 2 2 0 F-box-like FAD_binding_3 PF01494.19 CEH17113.1 - 6.5e-31 107.8 0.0 8.8e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CEH17113.1 - 2.4e-06 27.0 0.3 0.0032 16.7 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEH17113.1 - 4.2e-06 26.6 0.2 0.00041 20.1 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEH17113.1 - 8.9e-06 25.9 0.1 1.8e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CEH17113.1 - 1.7e-05 25.3 0.5 0.00013 22.4 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CEH17113.1 - 0.00067 18.6 0.0 1.2 7.9 0.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.24 CEH17113.1 - 0.0011 18.1 0.0 0.0027 16.8 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 CEH17113.1 - 0.0055 16.6 0.0 0.008 16.1 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 CEH17113.1 - 0.0083 15.8 0.2 0.014 15.1 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 CEH17113.1 - 0.034 12.9 0.1 0.76 8.4 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 CEH17113.1 - 0.047 12.9 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 CEH17113.1 - 0.047 12.8 0.1 0.086 11.9 0.1 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A XdhC_C PF13478.6 CEH17113.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Pkinase PF00069.25 CEH17115.1 - 2.8e-54 184.3 0.0 3.7e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17115.1 - 1.4e-30 106.5 0.0 1.9e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CEH17115.1 - 2.5e-16 59.2 0.2 4.7e-16 58.3 0.2 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 CEH17115.1 - 6.4e-05 22.4 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEH17115.1 - 0.00023 20.2 0.1 0.00037 19.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CEH17115.1 - 0.00025 20.5 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEH17115.1 - 0.00091 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family bZIP_1 PF00170.21 CEH17117.1 - 5.7e-07 29.5 8.8 5.7e-07 29.5 8.8 2.5 3 0 0 3 3 3 1 bZIP transcription factor DUF3472 PF11958.8 CEH17117.1 - 0.073 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) Glutaredoxin2_C PF04399.13 CEH17117.1 - 0.081 12.8 0.1 0.27 11.0 0.1 1.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DUF4407 PF14362.6 CEH17117.1 - 0.097 12.0 7.9 0.019 14.3 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FeoC PF09012.10 CEH17117.1 - 0.1 12.7 0.1 0.3 11.2 0.1 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator FUSC PF04632.12 CEH17117.1 - 1.5 7.2 10.4 2.1 6.7 2.2 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Meth_synt_2 PF01717.18 CEH17118.1 - 2.9e-148 493.4 0.0 4.7e-141 469.7 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CEH17118.1 - 2.8e-113 378.6 0.0 2e-106 356.0 0.0 3.1 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 CEH17118.1 - 0.00052 19.7 0.8 0.0015 18.2 0.8 1.9 1 0 0 1 1 1 1 Short C-terminal domain VbhA PF18495.1 CEH17118.1 - 0.11 12.4 0.0 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Antitoxin VbhA URO-D PF01208.17 CEH17118.1 - 0.18 11.0 0.0 14 4.7 0.0 2.9 3 0 0 3 3 3 0 Uroporphyrinogen decarboxylase (URO-D) RRM_1 PF00076.22 CEH17119.1 - 3e-12 46.2 0.0 0.0061 16.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mog1 PF04603.12 CEH17120.1 - 6e-33 114.1 0.0 8.4e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein LacAB_rpiB PF02502.18 CEH17122.1 - 1.4e-32 112.6 0.0 1.6e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4514 PF14986.6 CEH17122.1 - 0.0042 17.0 0.6 0.012 15.6 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4514) ECH_2 PF16113.5 CEH17123.1 - 6.6e-90 302.0 0.0 4.1e-89 299.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CEH17123.1 - 3.3e-23 82.3 0.0 3.7e-22 78.8 0.0 2.3 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF3684 PF12449.8 CEH17123.1 - 0.083 10.7 0.0 0.11 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) MFS_1 PF07690.16 CEH17124.1 - 5e-26 91.5 18.0 9.5e-26 90.5 18.0 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily UCR_Fe-S_N PF10399.9 CEH17124.1 - 2 7.8 7.6 1.1 8.7 1.9 2.9 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF4203 PF13886.6 CEH17126.1 - 1.7e-10 40.9 0.1 2.6e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF1180 PF06679.12 CEH17126.1 - 0.37 11.2 4.8 0.14 12.6 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF1772 PF08592.11 CEH17126.1 - 0.61 10.4 3.4 2.6 8.4 3.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) FeS_assembly_P PF01883.19 CEH17127.1 - 5.3e-12 45.7 0.0 1.2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein MoCF_biosynth PF00994.24 CEH17128.1 - 8.1e-55 184.4 0.2 3.2e-26 91.7 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 CEH17128.1 - 2.3e-32 111.9 0.3 4e-32 111.2 0.3 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 CEH17128.1 - 1.5e-11 44.3 0.2 5e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) T2SSE PF00437.20 CEH17128.1 - 8.8e-05 21.7 0.3 0.7 8.9 0.1 3.2 3 0 0 3 3 3 2 Type II/IV secretion system protein CarboxypepD_reg PF13620.6 CEH17128.1 - 0.053 13.8 0.6 0.44 10.9 0.1 2.5 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain FlgD_ig PF13860.6 CEH17128.1 - 0.084 12.7 0.0 18 5.3 0.0 2.8 2 0 0 2 2 2 0 FlgD Ig-like domain SNF2_N PF00176.23 CEH17129.1 - 6.1e-25 87.7 0.0 1.3e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 CEH17129.1 - 3.5e-13 49.6 0.0 1.1e-12 48.0 0.0 1.8 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase ResIII PF04851.15 CEH17129.1 - 1.3e-05 25.3 0.0 0.0011 19.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEH17129.1 - 6.5e-05 23.2 0.0 0.00089 19.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TP6A_N PF04406.14 CEH17130.1 - 3.2e-13 49.5 0.0 5.4e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase ubiquitin PF00240.23 CEH17130.1 - 0.15 11.8 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family Glyco_hydro_16 PF00722.21 CEH17131.1 - 3.5e-31 108.0 0.1 6.5e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Methyltransf_25 PF13649.6 CEH17131.1 - 6.1e-06 26.9 0.3 0.076 13.7 0.1 3.4 2 2 0 3 3 3 2 Methyltransferase domain PrmA PF06325.13 CEH17131.1 - 0.00064 19.2 0.0 0.0032 16.9 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) DUF3180 PF11377.8 CEH17131.1 - 0.0097 16.1 2.8 0.02 15.0 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3180) Methyltransf_23 PF13489.6 CEH17131.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 CEH17131.1 - 0.016 15.9 0.0 11 6.7 0.0 3.0 2 1 0 3 3 3 0 Methyltransferase domain TMEM154 PF15102.6 CEH17131.1 - 0.03 14.2 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family MTS PF05175.14 CEH17131.1 - 0.068 12.7 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Mito_carr PF00153.27 CEH17132.1 - 1.2e-14 54.0 0.4 2.6e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Pollen_allerg_2 PF01620.16 CEH17132.1 - 0.11 12.7 1.4 0.63 10.2 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) Abhydrolase_3 PF07859.13 CEH17133.1 - 2.5e-21 76.5 0.1 4.2e-18 66.0 0.0 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 CEH17133.1 - 0.00091 18.2 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family DUF2974 PF11187.8 CEH17133.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 CEH17133.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase ICMT PF04140.14 CEH17134.1 - 1.3e-15 57.6 0.6 2.2e-14 53.6 0.1 2.3 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CEH17134.1 - 1.2e-09 38.5 0.7 7.1e-08 32.8 0.3 2.5 2 0 0 2 2 2 1 Phospholipid methyltransferase SPRY PF00622.28 CEH17136.1 - 4.9e-07 29.9 0.0 4.1e-06 26.9 0.0 2.4 3 0 0 3 3 3 1 SPRY domain PEMT PF04191.13 CEH17137.1 - 9e-20 71.1 0.7 4.1e-13 49.6 0.0 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase RhoGAP PF00620.27 CEH17138.1 - 1.4e-43 148.3 0.0 2.4e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 CEH17138.1 - 5.5e-11 42.9 0.0 1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PX PF00787.24 CEH17138.1 - 7.5e-07 29.1 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 PX domain Aldo_ket_red PF00248.21 CEH17139.1 - 4.4e-30 104.9 0.0 2.9e-18 66.1 0.0 3.0 1 1 2 3 3 3 3 Aldo/keto reductase family ADH_N PF08240.12 CEH17140.1 - 1.1e-21 76.7 1.9 1.8e-21 76.1 1.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEH17140.1 - 2.9e-17 62.9 0.0 4.6e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CEH17140.1 - 0.0073 15.7 0.2 0.013 14.9 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEH17140.1 - 0.019 14.2 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 CEH17140.1 - 0.031 15.1 0.0 0.067 14.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 CEH17140.1 - 0.061 13.8 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Oxidored_nitro PF00148.19 CEH17140.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase RRM_1 PF00076.22 CEH17141.1 - 1.1e-71 236.6 1.2 1.8e-15 56.5 0.0 7.6 5 2 1 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CEH17141.1 - 7.1e-07 29.2 1.4 0.061 13.1 0.1 5.4 5 1 0 5 5 5 1 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 CEH17141.1 - 2.7e-05 24.2 3.1 0.013 15.5 0.0 5.0 6 0 0 6 6 6 1 Limkain b1 RRM_occluded PF16842.5 CEH17141.1 - 7.7e-05 22.5 0.0 2.4 8.1 0.0 4.7 5 0 0 5 5 5 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CEH17141.1 - 0.0029 17.7 0.0 6.2 7.0 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif RRM_2 PF04059.12 CEH17141.1 - 0.13 12.5 0.0 4.8 7.5 0.0 3.4 4 0 0 4 4 4 0 RNA recognition motif 2 Abhydrolase_2 PF02230.16 CEH17142.1 - 3.5e-28 98.9 0.0 1.5e-18 67.4 0.0 3.0 2 1 1 3 3 3 3 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CEH17142.1 - 0.048 12.9 0.0 0.081 12.2 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Sulfotransfer_3 PF13469.6 CEH17143.1 - 0.0023 18.3 0.3 0.12 12.7 0.3 2.8 1 1 0 1 1 1 1 Sulfotransferase family BEN PF10523.9 CEH17143.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 BEN domain LIP PF03583.14 CEH17144.1 - 2e-47 161.9 0.1 2.7e-47 161.5 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase GFA PF04828.14 CEH17145.1 - 0.00096 19.5 0.1 0.0018 18.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pro_isomerase PF00160.21 CEH17146.1 - 1.7e-46 158.4 0.2 1.9e-46 158.2 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltrn_RNA_3 PF02598.17 CEH17147.1 - 9.2e-93 310.8 0.0 1.2e-92 310.5 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Heme_oxygenase PF01126.20 CEH17148.1 - 1.7e-14 54.1 0.0 5.2e-11 42.7 0.0 2.9 2 1 0 2 2 2 2 Heme oxygenase Pkinase PF00069.25 CEH17149.1 - 2.9e-05 23.6 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CEH17149.1 - 3e-05 23.5 0.0 5.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH17149.1 - 0.0047 16.9 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEH17149.1 - 0.021 13.6 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 CEH17150.1 - 1.2e-47 162.4 0.0 1.7e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEH17150.1 - 2.4e-47 161.6 0.0 3.4e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 CEH17150.1 - 0.00026 20.8 2.0 0.00055 19.8 2.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 CEH17150.1 - 0.00074 19.7 0.9 0.0021 18.3 0.9 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CEH17150.1 - 0.0024 18.0 0.7 0.006 16.7 0.7 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain APH PF01636.23 CEH17150.1 - 0.0027 17.7 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEH17150.1 - 0.0038 16.6 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family C1_2 PF03107.16 CEH17150.1 - 0.0057 17.0 1.0 0.012 16.0 1.0 1.5 1 0 0 1 1 1 1 C1 domain Haspin_kinase PF12330.8 CEH17150.1 - 0.0085 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CEH17150.1 - 0.014 14.2 0.7 0.021 13.6 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase PHD PF00628.29 CEH17150.1 - 0.02 14.8 3.8 0.047 13.6 3.8 1.6 1 0 0 1 1 1 0 PHD-finger Kinase-like PF14531.6 CEH17150.1 - 0.14 11.5 0.0 0.37 10.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like UCR_14kD PF02271.16 CEH17152.1 - 9.2e-36 121.8 1.8 1e-35 121.6 1.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Dus PF01207.17 CEH17153.1 - 1.6e-61 208.1 0.0 4.8e-61 206.5 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TPR_2 PF07719.17 CEH17153.1 - 0.0033 17.4 6.1 0.067 13.3 0.9 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ThiG PF05690.14 CEH17153.1 - 0.0082 15.5 0.1 0.0082 15.5 0.1 1.7 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 CEH17153.1 - 0.009 15.4 0.2 0.023 14.1 0.2 1.6 1 0 0 1 1 1 1 Nitronate monooxygenase TPR_1 PF00515.28 CEH17153.1 - 0.023 14.5 1.6 0.023 14.5 1.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat AOX PF01786.17 CEH17154.1 - 1.3e-87 292.9 0.1 1.6e-87 292.7 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 CEH17154.1 - 0.052 13.3 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 RSN1_7TM PF02714.15 CEH17155.1 - 1.4e-66 224.7 22.3 2.2e-66 224.0 22.3 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CEH17155.1 - 9.2e-30 103.5 0.0 9.2e-30 103.5 0.0 3.1 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CEH17155.1 - 2.2e-17 63.8 0.0 3.8e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter HMA PF00403.26 CEH17156.1 - 2e-17 63.4 0.3 2.3e-17 63.2 0.3 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain TsaE PF02367.17 CEH17159.1 - 0.0014 18.7 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CEH17159.1 - 0.0021 18.2 0.0 0.0051 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CEH17159.1 - 0.0042 16.4 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin MobB PF03205.14 CEH17159.1 - 0.0056 16.6 0.0 0.046 13.6 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 CEH17159.1 - 0.0072 16.7 0.1 0.026 14.9 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CEH17159.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 CEH17159.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 CEH17159.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 CEH17159.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_7 PF12775.7 CEH17159.1 - 0.03 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 CEH17159.1 - 0.052 13.6 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CEH17159.1 - 0.066 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CEH17159.1 - 0.087 13.2 0.0 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 CEH17159.1 - 0.1 11.5 0.0 0.21 10.5 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 CEH17159.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CEH17159.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NTPase Alanine_zipper PF11839.8 CEH17160.1 - 1 9.8 11.1 0.76 10.2 3.9 2.6 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein NMO PF03060.15 CEH17161.1 - 3.4e-31 108.9 3.7 5.2e-23 81.9 0.3 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 CEH17161.1 - 0.0018 17.4 0.0 0.016 14.3 0.0 2.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CEH17161.1 - 0.0034 16.5 0.2 0.0054 15.8 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Jnk-SapK_ap_N PF09744.9 CEH17163.1 - 0.23 11.7 1.4 0.39 10.9 1.4 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 RRM_1 PF00076.22 CEH17164.1 - 1.2e-50 169.2 0.0 5.7e-17 61.3 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CEH17164.1 - 6.8e-05 22.9 0.0 0.14 12.2 0.0 3.1 3 0 0 3 3 3 2 Limkain b1 RRM_3 PF08777.11 CEH17164.1 - 0.00081 19.4 0.0 0.65 10.1 0.0 3.0 3 0 0 3 3 3 1 RNA binding motif ATP-grasp_2 PF08442.10 CEH17164.1 - 0.0015 18.1 0.0 1.4 8.5 0.0 3.3 3 0 0 3 3 3 1 ATP-grasp domain GRP PF07172.11 CEH17164.1 - 0.022 15.5 24.3 0.022 15.5 24.3 3.4 2 1 1 3 3 3 0 Glycine rich protein family RRM_5 PF13893.6 CEH17164.1 - 0.039 13.5 0.0 4.7 6.8 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PknH_C PF14032.6 CEH17164.1 - 0.039 13.8 0.1 26 4.6 0.0 3.1 3 0 0 3 3 3 0 PknH-like extracellular domain RRM_7 PF16367.5 CEH17164.1 - 0.18 11.9 0.0 14 5.8 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif RRM_Rrp7 PF17799.1 CEH17164.1 - 0.23 11.2 0.0 23 4.7 0.0 2.6 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Peptidase_M36 PF02128.15 CEH17165.1 - 2.5e-123 411.9 0.0 3.4e-123 411.5 0.0 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 CEH17165.1 - 3.3e-07 30.0 0.1 6.8e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif NAM-associated PF14303.6 CEH17166.1 - 6.7 7.4 6.0 10 6.8 0.0 2.2 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain Erv26 PF04148.13 CEH17167.1 - 5.4e-05 23.1 0.1 5.9e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 EI24 PF07264.11 CEH17167.1 - 0.00055 20.2 0.2 0.00061 20.1 0.2 1.0 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PRA1 PF03208.19 CEH17167.1 - 0.021 14.5 0.8 0.024 14.3 0.8 1.1 1 0 0 1 1 1 0 PRA1 family protein Cyt_bd_oxida_II PF02322.15 CEH17167.1 - 0.025 14.0 1.2 0.026 13.9 1.2 1.0 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF2721 PF11026.8 CEH17167.1 - 0.14 12.0 5.4 4 7.3 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Y_phosphatase2 PF03162.13 CEH17169.1 - 2e-42 144.6 0.0 2.4e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CEH17169.1 - 4.8e-09 36.5 0.0 8.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEH17169.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ABC_tran PF00005.27 CEH17170.1 - 1.1e-43 149.1 0.0 1.3e-24 87.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEH17170.1 - 6.6e-19 68.8 0.0 0.0023 17.8 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEH17170.1 - 1.1e-14 54.4 0.9 6.2e-05 22.5 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEH17170.1 - 5.5e-09 35.6 0.1 0.0049 16.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CEH17170.1 - 1.4e-06 28.9 7.4 0.014 15.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 CEH17170.1 - 3.2e-06 27.5 0.0 0.22 11.8 0.0 4.7 6 0 0 6 6 4 1 AAA domain DUF3730 PF12530.8 CEH17170.1 - 1.4e-05 24.8 0.6 0.14 11.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3730) DUF87 PF01935.17 CEH17170.1 - 2.4e-05 24.5 0.3 0.028 14.5 0.2 3.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 CEH17170.1 - 8.9e-05 22.4 2.7 0.2 11.3 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 CEH17170.1 - 0.0001 22.3 0.0 1 9.5 0.1 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase 4HB PF17947.1 CEH17170.1 - 0.00013 21.9 0.0 0.00068 19.7 0.0 2.2 1 0 0 1 1 1 1 Four helical bundle domain AAA PF00004.29 CEH17170.1 - 0.00015 22.2 0.0 3.8 7.9 0.0 5.0 4 1 1 5 5 5 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CEH17170.1 - 0.00015 22.0 0.0 0.89 9.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CEH17170.1 - 0.0002 21.3 0.0 0.36 10.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 CEH17170.1 - 0.00022 21.2 0.0 0.47 10.3 0.0 2.8 2 0 0 2 2 2 2 NACHT domain HEAT_EZ PF13513.6 CEH17170.1 - 0.00022 21.6 1.6 8.7 7.0 0.0 5.2 4 1 1 5 5 4 0 HEAT-like repeat AAA_18 PF13238.6 CEH17170.1 - 0.00027 21.5 0.0 0.35 11.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEH17170.1 - 0.00035 21.0 0.5 0.48 10.8 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain G-alpha PF00503.20 CEH17170.1 - 0.00038 19.7 0.0 0.17 11.0 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit MeaB PF03308.16 CEH17170.1 - 0.00096 18.2 0.1 0.069 12.1 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CEH17170.1 - 0.0015 18.2 0.1 11 5.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 CEH17170.1 - 0.0016 17.7 0.0 1.8 7.7 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.22 CEH17170.1 - 0.0016 18.8 0.0 2.6 8.5 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.6 CEH17170.1 - 0.0038 17.4 0.0 4.4 7.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain Chromo PF00385.24 CEH17170.1 - 0.004 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CLASP_N PF12348.8 CEH17170.1 - 0.0043 16.6 0.0 0.048 13.2 0.0 2.2 1 1 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 CEH17170.1 - 0.0047 17.1 2.0 0.18 12.1 0.0 4.3 5 0 0 5 5 3 1 HEAT repeat SbcCD_C PF13558.6 CEH17170.1 - 0.0053 17.0 0.0 0.21 11.9 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UME PF08064.13 CEH17170.1 - 0.0089 15.9 1.2 2.9 7.8 0.3 3.5 3 1 1 4 4 3 1 UME (NUC010) domain AAA_5 PF07728.14 CEH17170.1 - 0.0091 16.0 3.6 16 5.5 0.0 4.8 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 CEH17170.1 - 0.01 14.6 4.0 1.5 7.4 0.0 3.4 3 1 1 4 4 3 0 AAA domain EF-hand_7 PF13499.6 CEH17170.1 - 0.014 15.8 0.2 0.36 11.3 0.0 3.2 3 0 0 3 3 2 0 EF-hand domain pair AAA_24 PF13479.6 CEH17170.1 - 0.016 15.0 0.0 1.6 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF3437 PF11919.8 CEH17170.1 - 0.017 15.0 0.8 0.95 9.4 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) DUF815 PF05673.13 CEH17170.1 - 0.027 13.7 0.3 3.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 CEH17170.1 - 0.033 14.4 0.0 7.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 CEH17170.1 - 0.049 13.5 0.0 5.9 6.8 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_27 PF13514.6 CEH17170.1 - 0.078 12.6 0.5 9.7 5.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CEH17170.1 - 0.096 12.0 0.2 14 4.9 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 CEH17170.1 - 0.1 12.4 0.1 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TetR_C_16 PF17920.1 CEH17170.1 - 0.11 12.8 0.5 1.2 9.4 0.0 2.9 3 0 0 3 3 2 0 Tetracyclin repressor-like, C-terminal domain TsaE PF02367.17 CEH17170.1 - 0.11 12.5 0.1 24 5.0 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 CEH17170.1 - 0.12 11.9 0.1 16 5.0 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Urb2 PF10441.9 CEH17170.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Urb2/Npa2 family AAA_7 PF12775.7 CEH17170.1 - 0.2 11.2 0.1 17 4.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CEH17170.1 - 1.3 8.8 8.8 4.2 7.2 0.2 4.1 4 1 0 4 4 3 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 CEH17170.1 - 9.9 6.2 6.9 3.8 7.5 0.0 3.2 4 0 0 4 4 2 0 Dynamin family AFG1_ATPase PF03969.16 CEH17171.1 - 2.8e-88 296.2 0.1 1.5e-59 201.7 0.0 2.6 3 0 0 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.6 CEH17171.1 - 0.0014 19.0 0.0 0.0082 16.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEH17171.1 - 0.0027 18.0 0.0 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CEH17171.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CEH17171.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CEH17171.1 - 0.028 14.9 0.0 0.13 12.7 0.0 2.1 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 CEH17171.1 - 0.083 12.9 0.0 0.31 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CEH17171.1 - 0.1 13.0 0.1 0.94 9.9 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CEH17171.1 - 0.19 12.1 0.1 0.83 10.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase SRP9-21 PF05486.12 CEH17172.1 - 0.00037 20.8 0.1 0.0058 17.0 0.1 2.2 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Sin3a_C PF16879.5 CEH17176.1 - 1.1e-69 235.3 0.0 1.3e-67 228.6 0.0 3.2 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 CEH17176.1 - 3.5e-42 142.3 11.6 9.1e-18 64.1 0.0 3.9 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CEH17176.1 - 3.2e-33 113.7 0.3 7.6e-33 112.5 0.3 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor Hus1 PF04005.12 CEH17177.1 - 6.2e-65 219.2 0.2 7.1e-65 219.0 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein Noelin-1 PF12308.8 CEH17177.1 - 0.0075 16.2 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 Neurogenesis glycoprotein Agglutinin PF07468.11 CEH17177.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 Agglutinin domain SpoVIF PF14069.6 CEH17177.1 - 0.11 12.2 0.1 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 Stage VI sporulation protein F HAD_2 PF13419.6 CEH17180.1 - 3.5e-07 30.5 0.0 2.1e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEH17180.1 - 3.3e-06 27.1 0.0 6.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CEH17180.1 - 0.00072 19.9 0.0 0.0057 17.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SOG2 PF10428.9 CEH17180.1 - 0.79 8.9 13.8 1 8.4 13.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein GTP_EFTU PF00009.27 CEH17181.1 - 1.1e-49 168.6 0.0 2.2e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CEH17181.1 - 3.5e-42 142.9 0.3 6.4e-42 142.1 0.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CEH17181.1 - 8.7e-16 57.7 0.0 1.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 CEH17181.1 - 1.1e-07 31.9 0.0 2.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CEH17181.1 - 4.1e-06 27.1 0.1 8.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CEH17181.1 - 0.00038 20.3 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 CEH17181.1 - 0.00039 20.4 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II AIG1 PF04548.16 CEH17181.1 - 0.0038 16.6 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 CEH17181.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Ras family Cu-oxidase_3 PF07732.15 CEH17182.1 - 1.1e-30 106.1 1.9 2.8e-30 104.8 0.1 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 CEH17182.1 - 7.7e-22 78.1 0.0 4.2e-21 75.7 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CEH17182.1 - 2.9e-11 43.2 3.4 1.8e-06 27.7 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase MARVEL PF01284.23 CEH17186.1 - 0.00017 21.6 10.7 0.00024 21.1 10.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2207 PF09972.9 CEH17186.1 - 2.7 6.6 4.0 3.8 6.2 4.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CM_2 PF01817.21 CEH17189.1 - 0.0058 17.0 0.1 0.39 11.1 0.0 2.5 2 0 0 2 2 2 2 Chorismate mutase type II SGS PF05002.15 CEH17190.1 - 7e-31 106.2 2.1 1.6e-30 105.0 2.1 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.16 CEH17190.1 - 5.3e-13 49.8 0.1 8.9e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 CS domain DPBB_1 PF03330.18 CEH17191.1 - 1.8e-09 37.7 0.1 1.1e-08 35.2 0.0 2.3 2 0 0 2 2 2 1 Lytic transglycolase CDC45 PF02724.14 CEH17191.1 - 0.054 11.8 19.5 0.07 11.4 19.5 1.2 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 CEH17191.1 - 0.096 9.8 15.9 0.11 9.6 15.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 CEH17191.1 - 0.74 7.9 17.7 0.9 7.6 17.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOG2 PF10428.9 CEH17191.1 - 0.76 8.9 18.5 0.92 8.6 18.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 CEH17191.1 - 0.81 8.5 15.7 1.1 8.1 15.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 CEH17191.1 - 1.1 8.5 9.4 1.6 7.9 9.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF572 PF04502.13 CEH17191.1 - 1.4 8.4 23.7 1.9 8.0 23.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.9 CEH17191.1 - 1.7 7.1 18.2 2 6.9 18.2 1.1 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 CEH17191.1 - 3.1 6.5 14.9 4.7 5.9 14.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 CEH17191.1 - 3.9 7.7 17.4 5.9 7.1 17.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Lin-8 PF03353.15 CEH17191.1 - 7.2 6.1 22.3 10 5.6 22.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pneumo_att_G PF05539.11 CEH17193.1 - 5.5 6.5 6.0 8.4 5.9 6.0 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Aa_trans PF01490.18 CEH17194.1 - 6.4e-81 272.1 33.6 8e-81 271.8 33.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YpmT PF17431.2 CEH17194.1 - 0.12 12.5 2.4 1 9.5 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized YmpT-like DUF2269 PF10027.9 CEH17194.1 - 2.6 8.1 12.1 6.6 6.8 5.4 2.5 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Sugar_tr PF00083.24 CEH17195.1 - 2.2e-105 353.2 19.1 2.6e-105 352.9 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH17195.1 - 1.5e-22 80.0 32.7 3e-14 52.7 13.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily PSP1 PF04468.12 CEH17196.1 - 0.0031 17.8 1.3 3.9 7.8 0.0 2.9 3 0 0 3 3 3 2 PSP1 C-terminal conserved region GATA PF00320.27 CEH17198.1 - 4.2e-14 51.9 3.7 4.2e-14 51.9 3.7 1.9 2 0 0 2 2 2 1 GATA zinc finger PAS_3 PF08447.12 CEH17198.1 - 9.3e-11 41.9 0.0 2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 CEH17198.1 - 6.8e-06 26.3 0.0 2.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 CEH17198.1 - 8.5e-06 25.7 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 CEH17198.1 - 0.0066 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 CEH17198.1 - 0.033 14.3 0.1 0.07 13.3 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 CEH17198.1 - 0.14 11.7 1.2 0.39 10.3 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding DUF883 PF05957.13 CEH17198.1 - 2.7 8.7 6.9 0.42 11.2 1.5 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) UreF PF01730.16 CEH17199.1 - 5.9e-21 75.4 0.7 1.2e-20 74.4 0.7 1.5 1 0 0 1 1 1 1 UreF DHHC PF01529.20 CEH17200.1 - 4.7e-30 104.4 3.5 4.7e-30 104.4 3.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-tcix PF14952.6 CEH17200.1 - 0.0046 16.5 1.3 0.0087 15.7 1.3 1.3 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding DUF35_N PF12172.8 CEH17200.1 - 0.14 12.1 3.7 0.3 11.0 3.7 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 CEH17200.1 - 0.81 9.8 7.9 1.5 8.9 7.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon UBM PF14377.6 CEH17201.1 - 0.049 13.1 0.0 3.1 7.4 0.0 2.9 2 0 0 2 2 2 0 Ubiquitin binding region Mito_carr PF00153.27 CEH17202.1 - 3.5e-12 46.1 0.2 4.8e-05 23.2 0.0 4.3 4 0 0 4 4 4 3 Mitochondrial carrier protein Herpes_LMP1 PF05297.11 CEH17202.1 - 1.2 8.2 6.9 2.3 7.3 6.9 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Chalcone_2 PF16035.5 CEH17203.1 - 4.1e-34 118.2 0.8 1.7e-31 109.6 0.8 2.5 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 CEH17203.1 - 4.1e-06 27.0 0.0 0.00052 20.2 0.1 2.2 2 0 0 2 2 2 2 Chalcone isomerase-like ubiquitin PF00240.23 CEH17204.1 - 1.7e-09 37.3 0.0 1.9e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CEH17204.1 - 0.00011 22.6 0.1 0.00038 20.8 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 CEH17204.1 - 0.00025 20.8 0.0 0.00029 20.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 CEH17204.1 - 0.018 15.5 0.0 0.023 15.2 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RAWUL PF16207.5 CEH17204.1 - 0.071 13.8 0.0 0.086 13.5 0.0 1.2 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like EnY2 PF10163.9 CEH17205.1 - 2.6e-17 63.0 0.0 3.2e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 TPR_14 PF13428.6 CEH17205.1 - 0.071 14.0 1.0 0.18 12.7 0.4 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat DSBA PF01323.20 CEH17205.1 - 0.13 12.0 0.6 0.17 11.7 0.6 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Histone PF00125.24 CEH17206.1 - 2.3e-44 150.9 0.0 2.7e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CEH17206.1 - 0.00038 20.6 0.0 0.00056 20.0 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CEH17206.1 - 0.005 17.2 0.0 0.0072 16.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CEH17206.1 - 0.027 14.7 0.3 0.1 12.9 0.2 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEH17206.1 - 0.034 14.2 0.1 0.05 13.7 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PP2C PF00481.21 CEH17207.1 - 4.1e-34 118.4 0.0 4.9e-31 108.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C DUF3445 PF11927.8 CEH17208.1 - 2.2e-49 168.1 0.0 2.9e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) 2OG-FeII_Oxy_3 PF13640.6 CEH17210.1 - 0.042 14.7 0.0 0.075 13.9 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF1479 PF07350.12 CEH17211.1 - 2.1e-133 445.1 0.0 4e-133 444.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1479) FAD_binding_4 PF01565.23 CEH17212.1 - 1.4e-23 83.2 0.1 2.5e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain N6-adenineMlase PF10237.9 CEH17213.1 - 1.1e-36 126.0 0.0 1.6e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Haspin_kinase PF12330.8 CEH17213.1 - 0.043 12.8 1.2 0.067 12.1 1.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TEX13 PF15186.6 CEH17213.1 - 0.59 9.8 7.2 1 9.1 7.1 1.4 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family Aa_trans PF01490.18 CEH17214.1 - 1.1e-59 202.3 5.9 1.3e-59 201.9 5.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2107 PF09880.9 CEH17214.1 - 0.085 13.0 3.6 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2107) Saf_2TM PF18303.1 CEH17214.1 - 0.95 9.0 3.2 4.2 7.0 3.2 2.1 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain SET PF00856.28 CEH17215.1 - 7.2e-06 26.5 0.0 5.2e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 SET domain Pkinase PF00069.25 CEH17216.1 - 9.8e-62 208.7 0.0 1.4e-61 208.2 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17216.1 - 3.8e-33 114.9 0.0 4.8e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEH17216.1 - 0.00089 18.7 0.4 0.0034 16.8 0.4 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEH17216.1 - 0.0014 17.6 0.1 0.002 17.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEH17216.1 - 0.0017 18.3 0.4 0.031 14.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CEH17216.1 - 0.0049 16.2 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Phage_sheath_1C PF17482.2 CEH17216.1 - 0.035 14.1 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain Pkinase_fungal PF17667.1 CEH17216.1 - 0.068 11.9 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YukC PF10140.9 CEH17216.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Acid_PPase PF12689.7 CEH17217.1 - 2.6e-55 186.9 0.0 3.2e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase SMI1_KNR4 PF09346.10 CEH17218.1 - 3.4e-23 82.5 0.0 7.9e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DUF2442 PF10387.9 CEH17218.1 - 0.058 13.7 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) EAF PF09816.9 CEH17220.1 - 6.8e-11 42.5 0.0 1.4e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Uds1 PF15456.6 CEH17221.1 - 5.5e-21 75.1 1.2 5.5e-21 75.1 1.2 9.4 6 2 2 9 9 9 3 Up-regulated During Septation Tweety PF04906.13 CEH17221.1 - 1.6 7.4 4.2 1.5 7.4 1.2 2.5 2 0 0 2 2 2 0 Tweety Mpv17_PMP22 PF04117.12 CEH17222.1 - 9.3e-07 29.0 0.2 1.2e-06 28.7 0.2 1.1 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3337 PF11816.8 CEH17224.1 - 1.7e-42 145.2 0.0 6.4e-28 97.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.32 CEH17224.1 - 6.2e-13 49.0 24.6 6.9e-05 23.5 0.2 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH17224.1 - 0.00022 21.4 0.1 0.0081 16.4 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEH17224.1 - 0.061 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RAWUL PF16207.5 CEH17224.1 - 0.12 13.1 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like RPAP2_Rtr1 PF04181.13 CEH17225.1 - 3.6e-11 43.2 0.2 7.5e-11 42.2 0.2 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Flu_M1_C PF08289.11 CEH17225.1 - 0.16 12.2 2.4 2.6 8.3 0.2 2.9 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain SpoIIE PF07228.12 CEH17226.1 - 7.3e-07 29.3 0.0 4.2e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CEH17226.1 - 9.6e-06 25.4 0.0 3.5e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CEH17226.1 - 0.00038 20.2 0.0 0.0027 17.4 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C G6PD_C PF02781.16 CEH17227.1 - 2.8e-104 348.4 0.0 3.5e-104 348.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CEH17227.1 - 1.3e-58 198.5 0.0 1.9e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Tubulin PF00091.25 CEH17228.1 - 4.4e-69 232.6 0.0 9.9e-69 231.5 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEH17228.1 - 1.1e-45 154.8 0.3 4.1e-33 114.2 0.1 2.3 1 1 1 2 2 2 2 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CEH17228.1 - 8.1e-06 26.1 0.0 2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CEH17228.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CEH17228.1 - 0.0079 15.4 0.0 0.024 13.9 0.0 1.7 2 0 0 2 2 2 1 Tubulin like NlpE_C PF17185.4 CEH17228.1 - 0.12 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 NlpE C-terminal OB domain Zn_clus PF00172.18 CEH17230.1 - 3.9e-06 26.9 7.9 6.3e-06 26.2 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dmrt1 PF12374.8 CEH17230.1 - 9.8 6.7 9.7 59 4.2 5.5 3.0 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 GTP_EFTU PF00009.27 CEH17231.1 - 8.3e-57 191.9 0.2 1.2e-56 191.4 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEH17231.1 - 3e-24 85.5 0.0 6e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEH17231.1 - 2.6e-15 56.6 3.7 3.5e-15 56.1 2.6 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEH17231.1 - 4.9e-05 23.4 0.1 9e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEH17231.1 - 0.0028 17.6 0.1 0.0063 16.4 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 CEH17231.1 - 0.0051 16.4 0.7 0.008 15.8 0.1 1.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CEH17231.1 - 0.014 15.2 0.2 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sec61_beta PF03911.16 CEH17232.1 - 3.7e-17 62.1 1.0 4.9e-17 61.7 1.0 1.2 1 0 0 1 1 1 1 Sec61beta family Methyltransf_11 PF08241.12 CEH17235.1 - 4.9e-21 75.2 0.0 7.9e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH17235.1 - 7.6e-18 65.0 0.0 1.3e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH17235.1 - 1.4e-14 54.1 0.0 1.9e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH17235.1 - 2.4e-12 47.5 0.0 4e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEH17235.1 - 3.9e-12 46.0 0.0 5.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CEH17235.1 - 8.3e-09 35.5 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 CEH17235.1 - 0.0082 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_29 PF03141.16 CEH17235.1 - 0.026 13.1 0.0 0.034 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 CEH17235.1 - 0.039 13.8 0.0 0.05 13.4 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase MTS PF05175.14 CEH17235.1 - 0.051 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.18 CEH17235.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 NNMT_PNMT_TEMT PF01234.17 CEH17235.1 - 0.21 10.7 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF2457 PF10446.9 CEH17236.1 - 2.7 7.1 6.9 2.9 6.9 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ArAE_2 PF10334.9 CEH17238.1 - 8.1e-45 153.4 0.0 1.4e-44 152.6 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 CEH17238.1 - 4.1e-44 151.4 9.7 1.5e-38 133.0 5.8 3.4 3 1 0 3 3 3 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CEH17238.1 - 1.2e-09 38.3 14.3 1.2e-09 38.3 14.3 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like Fe-ADH PF00465.19 CEH17239.1 - 2.8e-92 309.4 0.0 3.5e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CEH17239.1 - 3.1e-12 46.7 0.0 6.5e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Lactamase_B PF00753.27 CEH17240.1 - 2.2e-11 44.1 1.6 8.2e-11 42.3 1.6 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEH17240.1 - 2.6e-06 27.1 0.6 8.4e-06 25.4 0.6 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Palm_thioest PF02089.15 CEH17241.1 - 3.3e-07 30.4 0.0 5.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 CEH17241.1 - 1.9e-06 27.8 0.0 7.3e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 CEH17241.1 - 9.4e-06 25.3 0.0 2.1e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 CEH17241.1 - 6.4e-05 22.7 0.1 0.0008 19.1 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 CEH17241.1 - 0.00096 18.6 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 CEH17241.1 - 0.001 19.3 0.6 0.0033 17.6 0.0 2.1 3 0 0 3 3 3 1 Thioesterase domain LCAT PF02450.15 CEH17241.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 CEH17241.1 - 0.084 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 p450 PF00067.22 CEH17242.1 - 6.9e-55 186.6 0.0 8.7e-41 140.1 0.2 3.1 2 1 0 2 2 2 2 Cytochrome P450 DUF676 PF05057.14 CEH17243.1 - 1.6e-05 24.5 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CEH17243.1 - 0.00046 20.0 0.0 0.00096 18.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 CEH17243.1 - 0.00054 19.9 0.0 0.00093 19.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 CEH17243.1 - 0.015 15.0 0.4 0.052 13.2 0.4 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold FMN_red PF03358.15 CEH17244.1 - 4.9e-10 39.4 0.1 8.9e-10 38.5 0.0 1.5 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CEH17244.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 CEH17244.1 - 0.13 12.5 0.1 0.39 10.9 0.1 1.7 1 1 0 1 1 1 0 Flavodoxin DUF3320 PF11784.8 CEH17245.1 - 0.1 12.6 1.1 6 6.9 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3320) ORC6 PF05460.13 CEH17247.1 - 6.4e-05 22.4 24.5 0.011 15.1 0.2 2.1 1 1 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) BRK PF07533.16 CEH17247.1 - 0.19 11.4 0.2 0.48 10.1 0.1 1.7 2 0 0 2 2 2 0 BRK domain Nucleo_P87 PF07267.11 CEH17247.1 - 0.53 9.1 5.8 0.7 8.7 5.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Hamartin PF04388.12 CEH17247.1 - 2.4 6.7 11.2 2.9 6.4 11.2 1.1 1 0 0 1 1 1 0 Hamartin protein SBDS PF01172.18 CEH17249.1 - 1.3e-15 57.2 0.1 4.6e-15 55.5 0.1 1.7 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein IU_nuc_hydro PF01156.19 CEH17250.1 - 5.1e-31 108.4 0.0 7.4e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ADH_N PF08240.12 CEH17251.1 - 7.1e-22 77.3 3.5 1.9e-21 76.0 3.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEH17251.1 - 3.6e-13 49.6 0.0 1.1e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEH17251.1 - 6.9e-07 30.4 0.0 1.5e-06 29.3 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase XdhC_C PF13478.6 CEH17251.1 - 0.0006 20.3 0.0 0.019 15.5 0.0 2.3 2 0 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 CEH17251.1 - 0.0035 16.7 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEH17251.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_C PF16653.5 CEH17253.1 - 1.1e-84 284.7 0.0 1.9e-84 283.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 CEH17253.1 - 1.2e-65 220.4 0.0 2.7e-65 219.3 0.0 1.6 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 CEH17253.1 - 3.9e-23 82.1 0.9 7.2e-23 81.3 0.2 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 CEH17253.1 - 2.9e-17 62.3 0.5 5.6e-17 61.4 0.5 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CEH17253.1 - 4.5e-05 24.1 0.0 0.0058 17.3 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.6 CEH17253.1 - 0.00033 20.6 0.1 0.00059 19.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 CEH17253.1 - 0.00038 20.5 0.1 0.0023 18.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 CEH17253.1 - 0.002 18.6 0.1 0.02 15.3 0.0 2.6 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 CEH17253.1 - 0.0052 17.5 0.1 0.61 10.9 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain F420_oxidored PF03807.17 CEH17253.1 - 0.029 15.0 0.0 0.076 13.6 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 CEH17253.1 - 0.15 12.5 0.6 11 6.6 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding TFIIF_beta PF02270.15 CEH17255.1 - 7.5e-29 99.7 0.5 1.3e-28 98.9 0.5 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 CEH17255.1 - 7.1e-17 62.4 0.0 1.5e-16 61.3 0.0 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 CEH17255.1 - 0.0064 17.3 1.4 0.015 16.1 1.5 1.7 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain ECM11 PF15463.6 CEH17255.1 - 0.11 13.1 0.7 0.24 12.0 0.2 1.7 1 1 0 1 1 1 0 Extracellular mutant protein 11 Tyr-DNA_phospho PF06087.12 CEH17256.1 - 4.3e-34 118.1 0.0 3.7e-25 88.7 0.0 2.2 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase PITH PF06201.13 CEH17257.1 - 1.1e-38 132.9 0.0 1.3e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain PBP_sp32 PF07222.12 CEH17257.1 - 0.17 11.4 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 MoaE PF02391.17 CEH17258.1 - 1.2e-35 122.2 0.0 1.5e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SUIM_assoc PF16619.5 CEH17259.1 - 0.075 13.1 0.1 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SOG2 PF10428.9 CEH17260.1 - 2.7 7.1 12.8 2.9 7.0 12.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1275 PF06912.11 CEH17262.1 - 3.2e-29 102.2 13.4 8.1e-29 100.9 13.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) TcpE PF12648.7 CEH17263.1 - 0.07 13.7 0.6 0.14 12.7 0.6 1.4 1 0 0 1 1 1 0 TcpE family Pkinase PF00069.25 CEH17265.1 - 1.4e-39 136.0 0.0 2.4e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17265.1 - 7.1e-29 100.9 0.0 9.3e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEH17265.1 - 0.0022 18.0 0.0 0.6 10.0 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CEH17265.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 CEH17265.1 - 0.041 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEH17265.1 - 0.076 11.8 0.1 0.15 10.9 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase NicO PF03824.16 CEH17267.1 - 6.4e-40 137.3 8.9 9.7e-37 126.8 0.9 2.6 3 0 0 3 3 3 2 High-affinity nickel-transport protein DUF4231 PF14015.6 CEH17267.1 - 3.5 8.1 9.7 4.2 7.9 1.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) YacG PF03884.14 CEH17268.1 - 0.02 14.6 0.1 0.052 13.3 0.1 1.6 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG Aminotran_1_2 PF00155.21 CEH17269.1 - 2.9e-44 151.7 0.0 3.8e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 CEH17269.1 - 0.011 14.4 0.0 0.023 13.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III Aldo_ket_red PF00248.21 CEH17270.1 - 3.5e-49 167.6 0.1 3.5e-47 161.0 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TrmE_N PF10396.9 CEH17270.1 - 0.046 14.0 0.0 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus GFO_IDH_MocA PF01408.22 CEH17270.1 - 0.1 13.4 0.2 0.84 10.5 0.2 2.1 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Eisosome1 PF12757.7 CEH17270.1 - 1.1 9.5 4.5 24 5.2 0.2 3.2 2 1 0 2 2 2 0 Eisosome protein 1 FAT PF02259.23 CEH17271.1 - 3.9e-70 236.8 9.0 8.7e-70 235.6 9.0 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CEH17271.1 - 4.4e-29 102.0 0.0 1.2e-28 100.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CEH17271.1 - 0.004 17.0 0.1 0.0098 15.7 0.1 1.7 1 0 0 1 1 1 1 FATC domain MRP-L46 PF11788.8 CEH17271.1 - 0.19 12.5 0.2 0.56 11.0 0.2 1.7 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 PI3_PI4_kinase PF00454.27 CEH17272.1 - 3.4e-34 118.8 0.0 2.1e-33 116.2 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 CEH17272.1 - 0.0089 16.0 3.1 0.029 14.3 3.1 1.9 1 1 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 CEH17272.1 - 0.01 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PI3Ka PF00613.20 CEH17272.1 - 0.013 14.9 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) FbpC_C_terminal PF17845.1 CEH17272.1 - 0.078 13.1 0.6 1.9 8.6 0.2 2.8 2 0 0 2 2 2 0 FbpC C-terminal regulatory nucleotide binding domain Paramyxo_C PF01692.18 CEH17272.1 - 0.14 11.5 0.3 0.31 10.4 0.3 1.5 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C DcpS_C PF11969.8 CEH17273.1 - 1.2e-14 54.8 1.3 7e-14 52.3 1.3 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CEH17273.1 - 3.4e-06 27.7 2.9 3.6e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 HIT domain FR47 PF08445.10 CEH17273.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein MGC-24 PF05283.11 CEH17273.1 - 0.54 10.7 5.0 1.7 9.1 2.4 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RNase_T PF00929.24 CEH17274.1 - 7.1e-28 98.2 0.0 8.7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Peptidase_C2 PF00648.21 CEH17275.1 - 2.7e-16 59.5 0.0 4.6e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CEH17275.1 - 2.3e-15 57.1 0.0 1.7e-07 31.6 0.0 4.7 3 2 0 3 3 3 3 Calpain large subunit, domain III MIT PF04212.18 CEH17275.1 - 0.0027 17.8 1.4 0.0048 16.9 1.4 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain CRCB PF02537.15 CEH17276.1 - 5.9e-22 77.8 20.3 1.6e-15 57.2 8.5 2.6 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) LON_substr_bdg PF02190.16 CEH17277.1 - 5.5e-23 81.9 0.0 1.3e-22 80.7 0.0 1.6 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 CEH17277.1 - 3.2e-06 27.2 3.0 6.9e-06 26.1 3.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CEH17277.1 - 1.6e-05 24.6 3.1 3e-05 23.8 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEH17277.1 - 2.9e-05 24.0 3.9 6.1e-05 23.0 3.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEH17277.1 - 0.00013 21.7 1.8 0.00027 20.7 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEH17277.1 - 0.00059 19.7 4.0 0.0012 18.6 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CEH17277.1 - 0.052 13.4 1.1 0.12 12.3 1.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CEH17277.1 - 0.11 12.3 1.9 0.23 11.3 1.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CEH17277.1 - 0.25 11.7 4.1 0.63 10.4 4.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 CEH17277.1 - 0.32 11.0 7.6 0.66 10.0 7.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain IPK PF03770.16 CEH17278.1 - 1.3e-50 172.0 0.0 2e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Alpha-L-AF_C PF06964.12 CEH17279.1 - 9.9e-25 87.6 0.1 2.6e-24 86.2 0.1 1.7 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain IF3_N PF05198.16 CEH17280.1 - 6.3e-07 29.6 0.4 1.5e-06 28.4 0.4 1.6 1 1 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain Abhydrolase_3 PF07859.13 CEH17281.1 - 1.9e-14 54.0 0.1 2.8e-11 43.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEH17281.1 - 2.4e-07 30.4 0.4 0.00024 20.7 0.0 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CEH17281.1 - 0.00013 22.6 3.3 0.00024 21.8 3.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEH17281.1 - 0.0039 16.9 0.1 0.23 11.0 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 CEH17281.1 - 0.0078 15.8 0.0 0.045 13.3 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 CEH17281.1 - 0.032 14.0 0.0 0.093 12.5 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Melibiase_2 PF16499.5 CEH17282.1 - 3.2e-19 69.2 2.2 3.2e-15 56.0 0.2 2.7 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 CEH17282.1 - 2e-11 43.8 0.2 3.9e-11 42.9 0.2 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 CEH17282.1 - 0.045 14.0 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain MDM1 PF15501.6 CEH17283.1 - 5.3e-05 22.6 4.7 5.9e-05 22.4 4.7 1.2 1 0 0 1 1 1 1 Nuclear protein MDM1 Macoilin PF09726.9 CEH17283.1 - 0.0047 15.6 2.7 0.0047 15.6 2.7 1.1 1 0 0 1 1 1 1 Macoilin family DUF4614 PF15391.6 CEH17283.1 - 0.0093 16.0 8.2 0.017 15.2 8.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) Apt1 PF10351.9 CEH17283.1 - 0.023 13.6 6.0 0.028 13.3 6.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CEH17283.1 - 0.063 13.2 12.7 0.076 12.9 12.7 1.1 1 0 0 1 1 1 0 SPX domain AF-4 PF05110.13 CEH17283.1 - 0.15 10.1 19.5 0.17 9.9 19.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Rrn6 PF10214.9 CEH17283.1 - 0.17 10.3 17.8 0.2 10.1 17.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PAP1 PF08601.10 CEH17283.1 - 0.18 11.5 10.1 0.22 11.2 10.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Peroxin-3 PF04882.12 CEH17283.1 - 0.46 9.4 5.0 0.64 8.9 5.0 1.2 1 0 0 1 1 1 0 Peroxin-3 Secretin_N_2 PF07655.13 CEH17283.1 - 0.5 10.9 16.8 0.85 10.2 16.8 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain CCDC106 PF15794.5 CEH17283.1 - 0.74 9.5 10.4 1.1 8.9 10.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF1635 PF07795.11 CEH17283.1 - 0.84 9.5 4.3 1.4 8.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Miga PF10265.9 CEH17283.1 - 1.4 7.9 5.7 1.7 7.5 5.7 1.1 1 0 0 1 1 1 0 Mitoguardin NPR3 PF03666.13 CEH17283.1 - 1.5 7.5 7.4 2 7.1 7.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CEH17283.1 - 4.9 5.8 4.9 6.7 5.4 4.9 1.1 1 0 0 1 1 1 0 Presenilin CCDC24 PF15669.5 CEH17283.1 - 5.7 6.7 10.8 19 5.0 10.8 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family CorA PF01544.18 CEH17284.1 - 7e-18 65.0 5.3 3.8e-08 33.0 0.6 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein RAMP PF04901.13 CEH17284.1 - 0.11 12.5 0.2 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 Receptor activity modifying family Glyco_hydro_32N PF00251.20 CEH17286.1 - 1e-82 278.2 5.0 1.4e-82 277.7 5.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CEH17286.1 - 1.8e-07 31.3 1.0 5.8e-07 29.6 0.5 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal GYF PF02213.16 CEH17286.1 - 0.048 13.3 1.7 0.78 9.5 0.2 2.9 3 0 0 3 3 3 0 GYF domain Coatomer_WDAD PF04053.14 CEH17288.1 - 9.5e-138 460.0 0.0 1.6e-137 459.2 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CEH17288.1 - 2.8e-98 329.3 0.0 3.6e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CEH17288.1 - 8.3e-43 143.6 11.4 7.3e-08 33.0 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH17288.1 - 2.1e-12 47.2 0.1 0.0015 18.8 0.0 6.4 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CEH17288.1 - 0.063 12.0 0.2 0.45 9.2 0.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like TPR_2 PF07719.17 CEH17288.1 - 0.29 11.4 1.8 6.2 7.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Nup160 PF11715.8 CEH17288.1 - 0.75 8.4 5.5 2.7 6.6 0.0 3.2 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Glyco_transf_90 PF05686.12 CEH17291.1 - 3.9e-24 85.3 0.0 7.5e-24 84.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 Nucleoporin_FG2 PF15967.5 CEH17291.1 - 0.049 12.2 1.3 0.068 11.7 1.3 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region DUF1929 PF09118.11 CEH17292.1 - 0.084 13.2 0.1 0.093 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) MARVEL PF01284.23 CEH17293.1 - 1.9e-05 24.7 8.3 3.4e-05 23.9 8.3 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.6 CEH17293.1 - 0.028 14.9 0.8 0.028 14.9 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Ndc1_Nup PF09531.10 CEH17293.1 - 2.6 6.6 5.2 0.21 10.3 0.7 1.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF4013 PF13197.6 CEH17293.1 - 7.3 6.4 15.1 31 4.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) WD40 PF00400.32 CEH17294.1 - 0.51 11.3 11.4 8 7.5 0.1 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat Sugar_tr PF00083.24 CEH17295.1 - 9.7e-114 380.7 18.9 1.1e-113 380.5 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH17295.1 - 6e-19 68.2 36.2 6e-19 68.2 36.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 CEH17296.1 - 7e-11 42.2 0.0 2.8e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Lactamase_B PF00753.27 CEH17297.1 - 3e-06 27.4 2.0 0.00066 19.7 0.3 2.5 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEH17297.1 - 0.0059 16.1 0.1 0.014 14.9 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain zf-HIT PF04438.16 CEH17298.1 - 2.4e-05 24.1 10.5 2.4e-05 24.1 10.5 1.6 2 0 0 2 2 2 1 HIT zinc finger zf-B_box PF00643.24 CEH17298.1 - 1.5 9.0 9.2 2.7 8.2 9.2 1.3 1 0 0 1 1 1 0 B-box zinc finger DWNN PF08783.11 CEH17299.1 - 2e-26 92.0 0.0 3.8e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 CEH17299.1 - 2.9e-08 33.4 6.0 5e-08 32.6 6.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CEH17299.1 - 0.00019 21.3 1.8 0.00019 21.3 1.8 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CEH17299.1 - 0.0014 18.6 0.7 0.0014 18.6 0.7 1.8 2 0 0 2 2 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 CEH17299.1 - 0.011 15.6 12.1 0.011 15.6 12.1 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEH17299.1 - 0.13 12.7 10.8 0.26 11.6 10.8 1.6 1 0 0 1 1 1 0 Ring finger domain zf-CCHC_5 PF14787.6 CEH17299.1 - 0.14 11.9 0.8 0.37 10.5 0.8 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C3HC4_4 PF15227.6 CEH17299.1 - 0.15 12.2 12.3 0.32 11.2 12.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CEH17299.1 - 0.79 9.6 14.6 0.033 14.0 8.9 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEH17299.1 - 2.8 7.9 13.0 4.9 7.1 13.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEH17299.1 - 5.4 7.1 9.0 11 6.1 9.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Rer1 PF03248.13 CEH17300.1 - 4.4e-73 244.6 0.0 5.2e-73 244.4 0.0 1.0 1 0 0 1 1 1 1 Rer1 family Peptidase_M1 PF01433.20 CEH17301.1 - 1.2e-34 119.8 0.0 1.7e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CEH17301.1 - 1.8e-32 111.8 0.2 3e-32 111.1 0.2 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CEH17301.1 - 6.1e-17 62.4 0.0 1.8e-16 60.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Aldedh PF00171.22 CEH17302.1 - 2.7e-120 402.0 0.0 4.3e-120 401.4 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Regulator_TrmB PF11495.8 CEH17302.1 - 0.22 10.7 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB SQHop_cyclase_C PF13243.6 CEH17304.1 - 4.4e-57 193.6 1.6 1e-51 176.0 1.1 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CEH17304.1 - 1.2e-50 172.2 0.6 6e-43 147.0 0.1 3.4 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 CEH17304.1 - 3.5e-27 93.8 12.6 6.1e-08 32.3 0.2 6.4 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 CEH17304.1 - 8.8e-06 25.0 0.0 0.0013 17.9 0.0 3.7 2 1 2 4 4 4 1 A-macroglobulin TED domain Pec_lyase PF09492.10 CEH17304.1 - 0.031 13.6 0.0 7 5.9 0.0 3.9 4 1 1 5 5 5 0 Pectic acid lyase AAA_2 PF07724.14 CEH17305.1 - 2.3e-16 60.4 0.0 7.4e-13 49.0 0.0 2.3 1 1 1 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CEH17305.1 - 1.4e-09 38.4 0.0 2.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEH17305.1 - 6.1e-05 23.5 0.4 0.00025 21.5 0.2 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CEH17305.1 - 8.5e-05 22.6 0.2 0.00024 21.1 0.2 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CEH17305.1 - 0.00016 21.4 0.7 0.00055 19.6 0.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEH17305.1 - 0.00056 19.7 0.4 0.00099 18.9 0.4 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CEH17305.1 - 0.00097 18.6 2.6 0.29 10.5 0.2 3.0 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CEH17305.1 - 0.00098 19.4 0.1 0.0034 17.7 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CEH17305.1 - 0.0013 18.9 0.1 0.0061 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 CEH17305.1 - 0.0038 16.4 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain ABC_tran PF00005.27 CEH17305.1 - 0.01 16.3 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CEH17305.1 - 0.026 14.6 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CEH17305.1 - 0.026 14.2 0.0 0.28 10.9 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CEH17305.1 - 0.029 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.6 CEH17305.1 - 0.041 13.7 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 CEH17305.1 - 0.048 12.9 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 CEH17305.1 - 0.069 13.1 0.0 0.84 9.7 0.0 2.4 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 CEH17305.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 CEH17305.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CEH17305.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ClpB_D2-small PF10431.9 CEH17305.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_18 PF13238.6 CEH17305.1 - 0.17 12.4 0.1 0.9 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 CEH17305.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CEH17305.1 - 0.23 11.9 0.0 0.46 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 CEH17305.1 - 0.23 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Pox_A32 PF04665.12 CEH17305.1 - 0.23 10.9 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein YCII PF03795.14 CEH17307.1 - 2.8e-06 27.7 0.0 7.6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 YCII-related domain Complex1_49kDa PF00346.19 CEH17308.1 - 4.1e-122 406.5 0.0 5.2e-122 406.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CEH17308.1 - 0.0015 17.6 0.0 0.003 16.5 0.0 1.5 1 1 0 1 1 1 1 Nickel-dependent hydrogenase Zn_Tnp_IS1 PF03811.13 CEH17308.1 - 0.054 13.2 0.2 13 5.6 0.0 2.4 2 0 0 2 2 2 0 InsA N-terminal domain NIF PF03031.18 CEH17310.1 - 7.2e-23 81.1 0.0 1.1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 CEH17310.1 - 0.00011 21.9 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Adaptin_N PF01602.20 CEH17311.1 - 4.8e-52 177.2 2.3 5.9e-52 176.9 2.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CEH17311.1 - 7.8e-12 45.5 1.4 4.1e-10 39.9 0.0 2.6 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CEH17311.1 - 2.4e-05 24.5 0.8 0.00015 21.9 0.1 2.6 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 CEH17311.1 - 2.6e-05 24.5 9.1 0.0014 19.0 0.9 4.4 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 CEH17311.1 - 0.014 15.6 0.6 3.2 8.2 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat Arm_2 PF04826.13 CEH17311.1 - 0.027 13.9 0.1 0.085 12.3 0.1 1.9 1 1 0 1 1 1 0 Armadillo-like CinA PF02464.17 CEH17312.1 - 1.5e-33 115.6 0.1 1.6e-33 115.4 0.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein CLTH PF10607.9 CEH17313.1 - 2.1e-09 37.5 0.0 3.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CEH17313.1 - 2.4e-07 30.7 0.5 4.1e-07 29.9 0.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEH17313.1 - 0.00021 21.1 0.9 0.00036 20.4 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH17313.1 - 0.00028 20.8 0.7 0.00047 20.1 0.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CEH17313.1 - 0.0029 17.7 1.0 0.0058 16.8 1.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CEH17313.1 - 0.0033 17.2 0.8 0.0063 16.3 0.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CEH17313.1 - 0.0068 16.3 0.8 0.012 15.5 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEH17313.1 - 0.0099 16.2 1.5 0.019 15.3 1.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEH17313.1 - 0.13 12.1 1.5 0.23 11.3 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Alg14 PF08660.11 CEH17314.1 - 2.6e-50 170.8 0.0 8.7e-50 169.1 0.0 1.8 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Homeodomain PF00046.29 CEH17316.1 - 1.8e-16 59.7 1.9 4e-16 58.6 1.9 1.6 1 0 0 1 1 1 1 Homeodomain BrkDBD PF09607.10 CEH17316.1 - 0.0055 16.4 0.4 0.027 14.3 1.0 1.9 2 0 0 2 2 2 1 Brinker DNA-binding domain MRP-L20 PF12824.7 CEH17316.1 - 0.0064 16.7 0.2 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Cadherin_tail PF15974.5 CEH17316.1 - 0.038 14.3 0.5 0.13 12.5 0.3 2.0 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region HemS PF05171.12 CEH17316.1 - 0.17 11.9 0.0 0.51 10.3 0.0 1.8 1 1 0 1 1 1 0 Haemin-degrading HemS.ChuX domain Clr2_transil PF16761.5 CEH17317.1 - 8.2e-16 58.6 0.3 1.6e-15 57.7 0.3 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 CEH17317.1 - 4.6e-12 46.9 0.0 2.3e-10 41.4 0.0 2.9 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 WW PF00397.26 CEH17317.1 - 2.9e-06 27.2 0.2 6.4e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 WW domain TIMELESS PF04821.14 CEH17318.1 - 2.9e-62 210.5 0.0 6.2e-62 209.4 0.0 1.6 1 0 0 1 1 1 1 Timeless protein DUF1295 PF06966.12 CEH17319.1 - 1.1e-34 120.0 0.1 2.2e-31 109.2 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1295) AMP-binding PF00501.28 CEH17320.1 - 3e-72 243.5 0.0 1.1e-71 241.7 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEH17320.1 - 5.2e-20 72.2 0.4 1.1e-19 71.2 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain VMA21 PF09446.10 CEH17322.1 - 0.16 12.1 0.1 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 VMA21-like domain UvrD_C PF13361.6 CEH17323.1 - 3.2e-60 204.4 0.1 1.1e-32 113.7 0.1 2.5 2 1 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 CEH17323.1 - 6.2e-60 203.3 0.4 1.5e-59 202.1 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 CEH17323.1 - 8.7e-27 94.2 0.0 2.9e-26 92.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CEH17323.1 - 1.7e-09 37.3 0.1 5.1e-09 35.8 0.1 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CEH17323.1 - 0.00087 19.1 0.0 0.076 12.7 0.0 2.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Rab5-bind PF09311.11 CEH17323.1 - 0.015 14.7 1.9 0.027 13.9 1.0 2.0 1 1 0 1 1 1 0 Rabaptin-like protein AAA_22 PF13401.6 CEH17323.1 - 0.028 14.7 0.2 0.2 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arg_tRNA_synt_N PF03485.16 CEH17323.1 - 0.057 14.0 0.8 0.84 10.3 0.1 2.9 3 0 0 3 3 3 0 Arginyl tRNA synthetase N terminal domain Sec7 PF01369.20 CEH17324.1 - 5.1e-33 114.3 1.1 8e-33 113.6 1.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 CEH17324.1 - 1.6e-10 41.4 0.0 4.6e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CEH17324.1 - 2.4e-09 37.6 0.0 4.8e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Myticin-prepro PF10690.9 CEH17325.1 - 2.3 8.5 5.7 1.7 8.9 4.4 1.4 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel adh_short PF00106.25 CEH17326.1 - 1.6e-86 288.8 11.7 1.9e-43 148.2 1.7 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEH17326.1 - 5.4e-71 238.9 12.3 2.9e-37 128.5 2.9 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH17326.1 - 6.6e-30 104.4 5.3 1.6e-15 57.5 0.6 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 CEH17326.1 - 5.1e-27 93.9 0.0 1.6e-26 92.3 0.0 1.9 2 0 0 2 2 2 1 MaoC like domain THF_DHG_CYH_C PF02882.19 CEH17326.1 - 1.4e-05 24.5 0.1 0.014 14.7 0.1 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 CEH17326.1 - 0.00052 19.4 0.5 0.058 12.7 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CEH17326.1 - 0.0018 18.2 6.3 0.27 11.1 0.6 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2690 PF10901.8 CEH17326.1 - 0.06 13.6 0.4 6.6 7.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2690) PglL_A PF15864.5 CEH17326.1 - 1.6 8.5 8.2 10 6.0 1.0 2.7 2 0 0 2 2 2 0 Protein glycosylation ligase DUF543 PF04418.12 CEH17326.1 - 3.6 7.6 10.0 8.2 6.5 1.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF543) DUF1365 PF07103.11 CEH17327.1 - 5.1e-56 190.0 0.0 7e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Pyridoxal_deC PF00282.19 CEH17328.1 - 2.2e-67 227.4 0.0 3.5e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CEH17328.1 - 0.00087 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MutS_I PF01624.20 CEH17328.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 MutS domain I BLUF PF04940.12 CEH17329.1 - 8.6e-29 99.5 0.0 1.2e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Sensors of blue-light using FAD 2OG-FeII_Oxy PF03171.20 CEH17330.1 - 4.4e-11 43.2 0.0 9.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CEH17330.1 - 1.9e-09 38.3 0.0 3.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Redoxin PF08534.10 CEH17331.1 - 1.2e-29 102.9 0.1 1.4e-29 102.7 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CEH17331.1 - 2.9e-11 43.3 0.0 4.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family FAD_binding_4 PF01565.23 CEH17333.1 - 6.4e-19 68.1 0.3 1.1e-18 67.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Esterase PF00756.20 CEH17334.1 - 4.6e-44 151.0 0.0 5.6e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CEH17334.1 - 0.0038 16.5 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 CEH17334.1 - 0.066 12.1 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme STIMATE PF12400.8 CEH17335.1 - 3.3e-32 111.7 0.0 4.6e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 STIMATE family TUDOR PF00567.24 CEH17337.1 - 0.0012 18.8 0.0 0.0033 17.4 0.0 1.6 2 0 0 2 2 2 1 Tudor domain RP-C_C PF11800.8 CEH17337.1 - 0.0039 17.3 0.8 0.0039 17.3 0.8 2.0 2 0 0 2 2 2 1 Replication protein C C-terminal region SMN PF06003.12 CEH17337.1 - 0.005 16.1 9.9 0.0056 16.0 0.2 2.3 1 1 0 2 2 2 1 Survival motor neuron protein (SMN) Tudor_3 PF18115.1 CEH17337.1 - 0.0082 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain CDC45 PF02724.14 CEH17337.1 - 7 4.8 10.0 6.7 4.9 2.4 2.1 2 0 0 2 2 2 0 CDC45-like protein Pro_CA PF00484.19 CEH17338.1 - 3.7e-15 56.6 0.0 7.8e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 Carbonic anhydrase MFS_1 PF07690.16 CEH17339.1 - 1.8e-20 73.2 22.2 1.7e-15 56.8 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4500 PF14937.6 CEH17339.1 - 0.4 10.7 1.9 31 4.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) TRAM_LAG1_CLN8 PF03798.16 CEH17340.1 - 1.8e-28 99.6 13.5 2.3e-28 99.3 13.5 1.1 1 0 0 1 1 1 1 TLC domain GST_N PF02798.20 CEH17341.1 - 3.2e-08 33.8 0.0 5.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CEH17341.1 - 4.6e-08 33.2 0.0 7.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEH17341.1 - 7.7e-07 29.2 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CEH17341.1 - 3.3e-05 24.2 0.0 5.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEH17341.1 - 0.0012 18.9 0.0 0.0028 17.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.27 CEH17342.1 - 5.4e-66 218.6 3.6 3e-21 75.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TMEM135_C_rich PF15982.5 CEH17343.1 - 0.01 16.4 0.2 0.13 12.9 0.2 2.3 1 1 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 CEH17343.1 - 0.13 12.7 6.8 25 5.3 0.1 3.7 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF3493 PF11998.8 CEH17343.1 - 1.3 9.3 7.6 0.45 10.7 1.0 2.8 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 Oxidored_FMN PF00724.20 CEH17344.1 - 9.6e-40 136.9 0.0 1.3e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family YadA_stalk PF05662.14 CEH17344.1 - 0.047 14.1 1.2 1.8 9.0 1.2 2.8 1 1 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin DPBB_1 PF03330.18 CEH17345.1 - 1.6e-09 37.9 0.3 2.7e-09 37.2 0.3 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEH17345.1 - 1e-05 25.4 1.9 1.6e-05 24.7 1.9 1.6 1 1 0 1 1 1 1 Barwin family HypA PF01155.19 CEH17345.1 - 0.069 13.2 0.1 0.076 13.0 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_repr_REX1B PF14966.6 CEH17346.1 - 3.4e-08 34.0 1.2 0.002 18.8 0.0 3.0 2 1 1 3 3 3 2 DNA repair REX1-B WXG100 PF06013.12 CEH17346.1 - 0.57 10.4 5.2 31 4.9 1.0 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF515 PF04415.12 CEH17346.1 - 1.1 7.6 9.7 1.3 7.3 6.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF515) GDC-P PF02347.16 CEH17347.1 - 5e-07 28.9 0.5 2e-06 26.9 0.2 1.8 2 0 0 2 2 2 1 Glycine cleavage system P-protein Aminotran_5 PF00266.19 CEH17347.1 - 0.0019 17.2 0.1 0.0035 16.4 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CEH17347.1 - 0.002 17.5 0.1 0.003 16.9 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 CEH17348.1 - 9.4e-121 403.6 0.0 1.2e-120 403.3 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein Ribosomal_S17e PF00833.18 CEH17351.1 - 3.1e-59 198.2 0.0 3.8e-59 198.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.19 CEH17353.1 - 2.8e-24 85.5 0.1 3.7e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 API5 PF05918.11 CEH17356.1 - 0.013 14.4 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF1320 PF07030.12 CEH17356.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) TPMT PF05724.11 CEH17357.1 - 6.8e-34 117.4 0.0 8e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 CEH17357.1 - 5.1e-08 33.5 0.0 1e-07 32.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH17357.1 - 7.5e-08 32.4 0.0 9.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH17357.1 - 8.9e-08 32.7 0.0 2.6e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH17357.1 - 1.3e-07 31.5 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH17357.1 - 1.8e-06 28.6 0.0 4.6e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Sfi1 PF08457.10 CEH17358.1 - 8.7e-14 51.0 61.0 7e-10 38.1 51.2 2.7 1 1 1 2 2 2 2 Sfi1 spindle body protein GST_C_3 PF14497.6 CEH17358.1 - 0.047 13.9 0.1 0.31 11.3 0.0 2.3 2 1 1 3 3 3 0 Glutathione S-transferase, C-terminal domain Sfi1 PF08457.10 CEH17359.1 - 2.8e-08 32.8 17.4 0.00017 20.3 7.2 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein PGAP1 PF07819.13 CEH17362.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 CEH17362.1 - 0.005 16.1 0.0 0.012 14.9 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LCAT PF02450.15 CEH17362.1 - 0.0077 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CEH17362.1 - 0.013 16.2 0.2 0.037 14.6 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEH17362.1 - 0.017 14.7 0.1 0.074 12.7 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold adh_short_C2 PF13561.6 CEH17363.1 - 1.6e-59 201.3 5.9 1.9e-59 201.1 5.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH17363.1 - 3.1e-39 134.5 5.7 4e-39 134.1 5.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH17363.1 - 1.1e-11 45.0 2.9 1.5e-11 44.5 2.9 1.2 1 0 0 1 1 1 1 KR domain IQ PF00612.27 CEH17364.1 - 0.00023 20.7 0.9 0.00063 19.3 0.9 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif SR-25 PF10500.9 CEH17364.1 - 0.0012 18.5 10.7 0.0012 18.5 10.7 2.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CEH17364.1 - 0.0054 17.4 9.1 0.0054 17.4 9.1 4.2 3 1 1 4 4 4 1 Immortalisation up-regulated protein Acetyltransf_10 PF13673.7 CEH17365.1 - 9.2e-09 35.3 0.0 3.6e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEH17365.1 - 1.6e-07 31.6 0.0 2.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEH17365.1 - 6.3e-06 26.4 0.0 1.4e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 CEH17365.1 - 0.002 18.8 0.0 0.0044 17.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEH17365.1 - 0.014 15.4 0.1 0.051 13.5 0.1 1.8 1 1 0 1 1 1 0 FR47-like protein GNAT_acetyltr_2 PF13718.6 CEH17365.1 - 0.032 13.7 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 GFO_IDH_MocA PF01408.22 CEH17366.1 - 4.5e-26 92.0 2.0 5.7e-26 91.7 0.5 1.9 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 CEH17366.1 - 3.7e-06 27.6 0.8 7.1e-06 26.7 0.8 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CEH17366.1 - 0.14 12.6 0.5 0.83 10.1 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pex14_N PF04695.13 CEH17367.1 - 0.041 14.5 2.8 0.076 13.7 2.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_7 PF13176.6 CEH17367.1 - 0.72 10.0 4.8 3.6 7.8 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CEH17367.1 - 0.78 9.9 9.8 3.7 7.7 0.3 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 CEH17367.1 - 9.2 6.7 19.9 3.6 7.9 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat AhpC-TSA PF00578.21 CEH17368.1 - 1.5e-27 96.0 0.0 2.1e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEH17368.1 - 2.4e-18 66.2 0.0 3.9e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF3306 PF11748.8 CEH17368.1 - 0.00024 22.0 3.3 0.00024 22.0 3.3 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3306) AhpC-TSA_2 PF13911.6 CEH17368.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF4551 PF15087.6 CEH17368.1 - 3 6.6 12.9 3.8 6.2 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 CEH17368.1 - 3.8 6.1 12.0 4 6.0 12.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CHCH PF06747.13 CEH17369.1 - 3.5e-05 23.8 1.3 4.8e-05 23.4 1.3 1.2 1 0 0 1 1 1 1 CHCH domain Abhydrolase_1 PF00561.20 CEH17372.1 - 9.3e-12 45.1 0.1 4.6e-10 39.6 0.0 2.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 CEH17372.1 - 1.8e-09 37.7 0.0 5.3e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Bap31 PF05529.12 CEH17374.1 - 1.7e-39 134.8 13.2 4.9e-37 126.8 3.7 2.1 2 0 0 2 2 2 2 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CEH17374.1 - 3.3e-08 33.4 0.9 5.4e-08 32.7 0.9 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain LPP PF04728.13 CEH17374.1 - 0.017 15.5 2.4 0.017 15.5 2.4 1.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper SlyX PF04102.12 CEH17374.1 - 0.22 12.1 0.3 0.22 12.1 0.3 2.4 3 0 0 3 3 3 0 SlyX DivIC PF04977.15 CEH17374.1 - 0.23 11.3 3.6 0.21 11.4 1.4 2.0 2 0 0 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 CEH17374.1 - 0.34 11.0 0.1 0.34 11.0 0.1 2.3 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 CEH17374.1 - 0.66 9.3 10.4 2 7.7 9.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Podoplanin PF05808.11 CEH17376.1 - 0.013 15.6 0.1 0.013 15.6 0.1 2.1 2 0 0 2 2 2 0 Podoplanin DUF2207 PF09972.9 CEH17376.1 - 0.031 13.1 0.0 0.099 11.4 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Bac_rhamnosid_C PF17390.2 CEH17376.1 - 0.038 13.8 1.0 0.32 10.8 0.0 2.6 3 0 0 3 3 3 0 Bacterial alpha-L-rhamnosidase C-terminal domain DUF2627 PF11118.8 CEH17376.1 - 0.18 12.4 0.0 0.32 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Metallophos PF00149.28 CEH17377.1 - 2e-12 48.0 1.2 2.7e-12 47.6 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 CEH17377.1 - 0.09 11.0 0.3 0.33 9.2 0.0 1.9 2 1 1 3 3 3 0 Firmicute fructose-1,6-bisphosphatase zf_C2H2_ZHX PF18387.1 CEH17379.1 - 0.0031 17.1 0.3 0.0049 16.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain 4F5 PF04419.14 CEH17379.1 - 0.0079 17.1 7.3 0.011 16.6 7.3 1.2 1 0 0 1 1 1 1 4F5 protein family Basic PF01586.16 CEH17379.1 - 0.045 14.9 0.6 0.067 14.4 0.6 1.3 1 0 0 1 1 1 0 Myogenic Basic domain zf-met2 PF12907.7 CEH17379.1 - 0.079 13.1 3.8 0.48 10.6 3.8 2.1 1 1 0 1 1 1 0 Zinc-binding zf-C2H2_4 PF13894.6 CEH17379.1 - 0.08 13.8 0.2 0.14 13.1 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DAO PF01266.24 CEH17381.1 - 1.5e-25 90.6 1.9 2.2e-25 90.0 1.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase PMI_typeI PF01238.21 CEH17381.1 - 0.081 12.1 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I ApbA PF02558.16 CEH17381.1 - 0.088 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GST_N PF02798.20 CEH17382.1 - 1.2e-14 54.4 0.0 2.3e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CEH17382.1 - 4.8e-11 42.9 0.0 1.1e-10 41.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEH17382.1 - 4.3e-09 36.5 0.0 7.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CEH17382.1 - 9.2e-07 29.0 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEH17382.1 - 2.4e-05 24.4 0.0 3.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEH17382.1 - 2.5e-05 24.2 0.1 5.7e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BolA PF01722.18 CEH17383.1 - 2.1e-12 47.1 0.0 5.9e-12 45.7 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein MFS_1 PF07690.16 CEH17385.1 - 2.4e-34 118.9 24.0 2.4e-34 118.9 24.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MASE2 PF05230.11 CEH17385.1 - 0.033 14.3 5.7 1.7 8.8 0.4 2.9 2 0 0 2 2 2 0 MASE2 domain Opy2 PF09463.10 CEH17386.1 - 0.00035 20.8 19.0 0.00057 20.2 19.0 1.3 1 0 0 1 1 1 1 Opy2 protein Myc_N PF01056.18 CEH17386.1 - 0.061 13.2 15.2 0.42 10.5 4.5 3.3 4 0 0 4 4 4 0 Myc amino-terminal region WD40 PF00400.32 CEH17387.1 - 5.1e-18 65.1 0.5 8.9e-08 32.7 0.6 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH17387.1 - 0.076 13.3 0.0 0.61 10.4 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CEH17388.1 - 4.3e-68 229.5 0.0 5.8e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17388.1 - 5.1e-36 124.3 0.0 7.6e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH17388.1 - 0.00017 21.0 0.0 0.00033 20.1 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEH17388.1 - 0.06 12.3 0.0 0.94 8.4 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CEH17388.1 - 0.15 10.8 0.0 0.15 10.8 0.0 2.3 3 0 0 3 3 3 0 Fungal protein kinase Osmo_CC PF08946.10 CEH17389.1 - 0.0099 16.1 0.6 6.3 7.1 0.0 3.0 2 0 0 2 2 2 2 Osmosensory transporter coiled coil Peptidase_S66 PF02016.15 CEH17389.1 - 0.065 13.3 0.6 0.22 11.7 0.6 2.0 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain DUF3461 PF11944.8 CEH17389.1 - 0.076 13.2 2.6 2.6 8.2 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3461) AAA_lid_7 PF17867.1 CEH17389.1 - 0.12 12.6 1.4 9.4 6.5 0.1 2.5 1 1 1 2 2 2 0 Midasin AAA lid domain Baculo_PEP_C PF04513.12 CEH17389.1 - 0.12 12.4 1.6 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MtrG PF04210.13 CEH17389.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.9 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G CoA_transf_3 PF02515.17 CEH17390.1 - 9.2e-87 291.5 1.9 7.7e-64 216.1 0.9 3.1 2 1 0 2 2 2 2 CoA-transferase family III Citrate_synt PF00285.21 CEH17391.1 - 1.8e-122 408.9 0.0 2.2e-122 408.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain CRAL_TRIO PF00650.20 CEH17392.1 - 7.7e-13 48.5 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain SLT PF01464.20 CEH17393.1 - 1.3e-12 47.4 0.0 3e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Transglycosylase SLT domain Macoilin PF09726.9 CEH17393.1 - 0.32 9.5 8.0 0.37 9.3 8.0 1.2 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 CEH17393.1 - 0.88 8.3 5.3 1.1 8.0 5.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CEH17393.1 - 2.2 6.9 5.1 3.2 6.4 5.1 1.1 1 0 0 1 1 1 0 Presenilin TPR_2 PF07719.17 CEH17394.1 - 0.00067 19.6 0.4 0.0023 17.9 0.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEH17394.1 - 0.0012 18.6 0.3 0.0028 17.4 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.18 CEH17394.1 - 0.019 15.0 0.2 0.046 13.8 0.2 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 CEH17394.1 - 0.059 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 TPR repeat TPR_7 PF13176.6 CEH17394.1 - 0.11 12.5 0.2 0.32 11.1 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEH17394.1 - 0.2 12.6 0.1 0.2 12.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SMBP PF16785.5 CEH17394.1 - 5.1 7.4 9.8 0.25 11.6 3.7 1.9 2 0 0 2 2 2 0 Small metal-binding protein PUL PF08324.11 CEH17395.1 - 5e-44 150.6 2.3 6.8e-44 150.2 2.3 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 CEH17395.1 - 5.1e-42 142.7 0.0 1.5e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CEH17395.1 - 5.2e-25 87.2 9.1 2.9e-05 24.8 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 CEH17395.1 - 0.0019 18.2 0.0 7.5 6.6 0.0 3.6 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Arm PF00514.23 CEH17395.1 - 0.035 14.2 0.2 0.23 11.6 0.1 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat WD40 PF00400.32 CEH17396.1 - 1.7e-28 98.2 11.5 0.0075 17.1 0.1 11.0 10 1 1 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH17396.1 - 5.4e-19 68.3 0.1 0.00028 21.1 0.0 6.4 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 CEH17396.1 - 2.1e-06 27.3 0.0 0.25 10.6 0.0 3.8 4 0 0 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 CEH17396.1 - 1e-05 24.7 6.9 0.13 11.2 0.0 5.4 4 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CEH17396.1 - 9.8e-05 22.2 0.2 1.1 9.3 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 CEH17396.1 - 0.0063 15.8 0.0 0.84 8.8 0.0 2.9 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 CEH17396.1 - 0.0099 14.6 0.1 0.51 8.9 0.0 3.0 3 0 0 3 3 3 1 Nucleoporin Nup120/160 TruB_C PF09142.11 CEH17396.1 - 6.8 6.6 8.1 2.6 7.9 0.4 3.7 3 1 1 4 4 4 0 tRNA Pseudouridine synthase II, C terminal Sel1 PF08238.12 CEH17397.1 - 9.3e-17 61.1 12.5 9.6e-09 35.7 0.4 5.6 5 0 0 5 5 5 4 Sel1 repeat TPR_6 PF13174.6 CEH17397.1 - 0.012 16.2 1.4 26 5.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEH17397.1 - 0.23 11.6 3.5 0.56 10.5 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PAS_9 PF13426.7 CEH17399.1 - 4.3e-27 94.4 0.0 4.6e-15 55.8 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 CEH17399.1 - 1.2e-15 57.5 0.0 1.1e-08 35.1 0.0 4.1 3 1 0 3 3 3 2 PAS fold PAS_3 PF08447.12 CEH17399.1 - 2.2e-15 56.7 0.0 1e-07 32.1 0.0 4.6 4 0 0 4 4 4 2 PAS fold PAS_4 PF08448.10 CEH17399.1 - 6.4e-08 32.8 0.3 8.4e-05 22.8 0.0 4.0 4 0 0 4 4 4 1 PAS fold PAS_8 PF13188.7 CEH17399.1 - 8.2e-06 25.7 0.0 0.056 13.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 CEH17399.1 - 0.00069 19.7 0.0 0.0074 16.4 0.0 2.6 2 0 0 2 2 2 1 PAS domain Enolase_C PF00113.22 CEH17400.1 - 5.7e-134 446.0 0.1 8e-134 445.5 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CEH17400.1 - 1.1e-53 180.9 0.1 1.9e-53 180.1 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CEH17400.1 - 1.6e-06 27.8 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CEH17400.1 - 0.084 12.0 0.6 0.16 11.1 0.1 1.6 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus YbaJ PF10757.9 CEH17401.1 - 0.018 15.6 0.1 0.037 14.6 0.1 1.4 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ DUF3493 PF11998.8 CEH17401.1 - 0.43 10.8 4.0 15 5.8 0.0 3.7 2 1 1 3 3 3 0 Low psii accumulation1 / Rep27 Hydantoinase_B PF02538.14 CEH17403.1 - 5.2e-217 721.3 0.0 6e-217 721.1 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase DUF2347 PF09804.9 CEH17404.1 - 1.4e-21 77.3 0.0 2.7e-21 76.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 CEH17404.1 - 0.09 13.3 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Mito_carr PF00153.27 CEH17405.1 - 1.1e-33 115.0 0.9 4.4e-16 58.6 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein NYN PF01936.18 CEH17406.1 - 5.1e-23 82.2 0.0 1e-22 81.2 0.0 1.4 1 0 0 1 1 1 1 NYN domain V-SNARE_C PF12352.8 CEH17407.1 - 6.7e-16 58.3 0.4 1.4e-15 57.3 0.4 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CEH17407.1 - 0.0001 22.2 0.1 0.00028 20.7 0.0 1.7 2 0 0 2 2 2 1 Sec20 DUF726 PF05277.12 CEH17408.1 - 2.3e-114 381.9 0.6 3e-114 381.5 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Methyltransf_11 PF08241.12 CEH17409.1 - 7.6e-12 45.7 0.0 1.5e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH17409.1 - 5.7e-11 43.0 0.0 1e-10 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH17409.1 - 4e-10 40.3 0.0 1.7e-09 38.3 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH17409.1 - 5.2e-09 36.2 0.0 7.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH17409.1 - 3.6e-06 26.8 0.0 5.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEH17409.1 - 0.00048 19.5 0.0 0.00071 19.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CAP_N PF01213.19 CEH17409.1 - 0.13 11.7 1.5 0.2 11.1 1.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Med3 PF11593.8 CEH17410.1 - 0.039 13.2 7.1 0.051 12.8 7.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRM_1 PF00076.22 CEH17411.1 - 5.1e-16 58.2 0.0 1e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEH17411.1 - 2.6e-06 27.4 0.0 4.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Chorismate_bind PF00425.18 CEH17412.1 - 1.6e-68 231.0 0.0 4.2e-68 229.7 0.0 1.7 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 CEH17412.1 - 8e-22 77.9 0.0 5.6e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 CEH17412.1 - 6.5e-07 29.7 0.0 0.11 12.7 0.0 3.4 2 1 0 2 2 2 2 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 CEH17412.1 - 0.00068 19.4 0.1 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase C26 ABC_tran PF00005.27 CEH17414.1 - 3.1e-32 112.0 0.4 5.2e-18 65.9 0.1 3.2 2 1 0 2 2 2 2 ABC transporter Chromo PF00385.24 CEH17414.1 - 2.5e-10 40.1 0.1 5.4e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_21 PF13304.6 CEH17414.1 - 3.1e-10 40.3 0.1 0.019 14.8 0.0 3.3 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEH17414.1 - 2.8e-09 36.7 0.0 0.035 13.5 0.0 3.6 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain HEAT_2 PF13646.6 CEH17414.1 - 4.2e-05 23.9 7.4 0.33 11.4 0.4 4.9 4 1 0 4 4 4 2 HEAT repeats 4HB PF17947.1 CEH17414.1 - 9.3e-05 22.4 0.1 0.00031 20.8 0.1 1.8 1 0 0 1 1 1 1 Four helical bundle domain HEAT PF02985.22 CEH17414.1 - 0.0002 21.3 0.8 23 5.6 0.0 5.7 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 CEH17414.1 - 0.00038 20.9 5.2 5.9 7.5 0.0 4.8 5 0 0 5 5 4 1 HEAT-like repeat CLASP_N PF12348.8 CEH17414.1 - 0.0014 18.3 0.2 0.0091 15.6 0.0 2.4 2 1 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.7 CEH17414.1 - 0.012 15.7 0.1 1.6 8.7 0.0 3.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 AAA_22 PF13401.6 CEH17414.1 - 0.017 15.4 0.2 1.1 9.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CEH17414.1 - 0.069 12.9 0.6 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CEH17414.1 - 0.076 13.5 2.9 0.14 12.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Adaptin_N PF01602.20 CEH17414.1 - 0.17 10.4 0.0 0.35 9.4 0.0 1.5 1 0 0 1 1 1 0 Adaptin N terminal region Acyl-CoA_dh_C PF12806.7 CEH17414.1 - 0.19 11.9 2.1 0.44 10.7 0.8 2.3 2 0 0 2 2 1 0 Acetyl-CoA dehydrogenase C-terminal like MMS19_C PF12460.8 CEH17414.1 - 0.97 8.5 3.0 19 4.2 0.1 2.7 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal ABC_tran_Xtn PF12848.7 CEH17414.1 - 2.8 8.0 9.3 0.25 11.4 0.7 3.0 3 0 0 3 3 3 0 ABC transporter zf-UBR PF02207.20 CEH17415.1 - 1.5e-08 34.7 7.7 1.5e-08 34.7 7.7 3.8 3 1 2 5 5 5 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 CEH17415.1 - 0.00024 21.0 1.0 0.00024 21.0 1.0 3.8 3 1 1 4 4 4 1 PHD-finger Zf_RING PF16744.5 CEH17415.1 - 0.0044 17.1 0.3 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 KIAA1045 RING finger BNIP3 PF06553.12 CEH17415.1 - 0.61 9.7 12.4 0.62 9.7 7.2 2.5 2 0 0 2 2 2 0 BNIP3 PHD_4 PF16866.5 CEH17415.1 - 4.3 7.5 8.3 0.28 11.3 0.6 2.9 3 0 0 3 3 3 0 PHD-finger CCAP PF11105.8 CEH17423.1 - 0.025 14.6 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a PIEZO PF15917.5 CEH17424.1 - 0.054 13.0 1.3 0.071 12.6 1.3 1.2 1 0 0 1 1 1 0 Piezo DUF3808 PF10300.9 CEH17424.1 - 0.2 10.4 2.6 0.54 8.9 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3808) Vps5 PF09325.10 CEH17425.1 - 0.015 14.9 15.2 0.023 14.3 15.1 1.4 1 1 0 1 1 1 0 Vps5 C terminal like DUF3552 PF12072.8 CEH17425.1 - 0.18 11.2 28.8 0.64 9.4 16.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Fez1 PF06818.15 CEH17425.1 - 2.4 8.6 25.6 0.33 11.4 7.0 2.2 1 1 1 2 2 2 0 Fez1 Apolipoprotein PF01442.18 CEH17426.1 - 1.6 8.6 61.9 0.11 12.4 47.0 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain TFIIA PF03153.13 CEH17426.1 - 2.1 8.3 27.6 2.9 7.8 27.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cache_3-Cache_2 PF17201.4 CEH17426.1 - 2.4 7.4 8.0 5.3 6.2 8.0 1.5 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain Whi5 PF08528.11 CEH17428.1 - 0.0043 16.6 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 Whi5 like LtrA PF06772.11 CEH17429.1 - 1.2e-31 110.2 33.9 1.6e-18 67.0 1.1 2.2 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) KbaA PF14089.6 CEH17429.1 - 0.026 14.4 7.7 0.014 15.2 4.7 2.0 2 0 0 2 2 2 0 KinB-signalling pathway activation in sporulation Cpn60_TCP1 PF00118.24 CEH17431.1 - 1.4e-85 287.8 5.6 2.7e-85 286.9 5.6 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M22 PF00814.25 CEH17432.1 - 1.9e-80 270.4 0.0 4.5e-66 223.3 0.0 3.2 1 1 1 2 2 2 2 Glycoprotease family Amidase PF01425.21 CEH17432.1 - 2.8e-66 224.3 0.0 1.7e-59 202.0 0.0 3.2 2 1 0 2 2 2 2 Amidase ELH PF02323.15 CEH17432.1 - 0.03 13.7 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Egg-laying hormone precursor Spermine_synth PF01564.17 CEH17432.1 - 0.12 11.8 0.2 17 4.7 0.0 2.3 2 0 0 2 2 2 0 Spermine/spermidine synthase domain NUFIP1 PF10453.9 CEH17433.1 - 4.7e-12 45.6 2.0 1.3e-11 44.1 2.0 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 CEH17433.1 - 2.2e-05 24.2 0.9 3.8e-05 23.5 0.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEH17433.1 - 0.00057 19.8 5.6 0.0011 18.9 5.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CEH17433.1 - 0.0032 17.2 2.5 0.0054 16.5 2.5 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CEH17433.1 - 0.0037 17.9 0.1 0.0037 17.9 0.1 2.2 2 0 0 2 2 2 1 Torus domain zf-RING_2 PF13639.6 CEH17437.1 - 9.8e-05 22.6 6.3 0.00011 22.4 3.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CEH17437.1 - 0.00089 19.5 3.0 0.0025 18.1 3.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEH17437.1 - 0.0016 18.3 2.1 0.0016 18.3 2.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH17437.1 - 0.0017 18.3 6.6 0.0076 16.2 6.6 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEH17437.1 - 0.0034 17.2 3.4 0.0034 17.2 3.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CEH17437.1 - 0.058 13.2 0.9 0.13 12.0 0.3 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CEH17437.1 - 0.16 11.8 6.6 0.11 12.3 2.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEH17437.1 - 0.56 10.3 3.3 1.5 8.9 0.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CEH17437.1 - 1.6 8.8 7.1 1.7 8.8 3.6 2.7 2 1 0 2 2 2 0 RING-type zinc-finger DUF4407 PF14362.6 CEH17437.1 - 2.9 7.2 8.0 0.11 11.9 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-RING-like PF08746.11 CEH17437.1 - 4.4 7.7 5.8 2.5 8.5 3.2 1.9 2 0 0 2 2 2 0 RING-like domain Asp-B-Hydro_N PF05279.11 CEH17437.1 - 7.2 6.6 9.7 0.54 10.3 4.9 1.5 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region tRNA_int_endo PF01974.17 CEH17438.1 - 4.6e-18 65.1 0.0 1.1e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 CEH17438.1 - 0.11 12.2 0.1 8 6.2 0.0 2.4 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain Cys_Met_Meta_PP PF01053.20 CEH17439.1 - 8.8e-55 185.8 0.0 1.3e-45 155.6 0.0 2.4 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Avl9 PF09794.9 CEH17440.1 - 1.8e-130 435.0 0.0 2.4e-130 434.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 CEH17440.1 - 4e-09 36.4 0.0 2e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 CEH17440.1 - 4.3e-08 33.1 0.0 3.1e-07 30.3 0.0 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 CEH17440.1 - 0.00041 20.9 0.0 0.00041 20.9 0.0 1.7 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 CEH17440.1 - 0.069 13.1 0.0 3.9 7.4 0.0 2.8 3 0 0 3 3 3 0 DENN (AEX-3) domain PhoLip_ATPase_C PF16212.5 CEH17441.1 - 3.8e-69 233.2 20.6 3.8e-69 233.2 20.6 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEH17441.1 - 1.9e-22 78.7 1.0 1.9e-22 78.7 1.0 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CEH17441.1 - 5.7e-20 71.2 0.0 5.2e-09 36.1 0.0 2.6 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEH17441.1 - 2.5e-10 41.0 0.4 1.1e-07 32.4 0.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEH17441.1 - 2.5e-07 30.4 3.6 4.5e-06 26.3 0.0 3.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEH17441.1 - 0.0005 19.9 0.2 0.0067 16.2 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 CEH17441.1 - 0.028 14.1 15.9 0.017 14.9 13.1 2.0 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus ATP_sub_h PF10775.9 CEH17445.1 - 0.14 12.2 0.1 0.14 12.2 0.1 2.3 3 0 0 3 3 3 0 ATP synthase complex subunit h Chromo_shadow PF01393.19 CEH17447.1 - 6.1e-15 55.1 0.7 7.4e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 CEH17447.1 - 1.4e-14 53.7 0.6 4.2e-14 52.2 0.6 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cwf_Cwc_15 PF04889.12 CEH17447.1 - 0.0012 18.6 40.3 0.0042 16.9 22.4 2.1 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein Spore_coat_CotO PF14153.6 CEH17447.1 - 0.65 9.9 24.9 0.31 10.9 8.9 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Merozoite_SPAM PF07133.11 CEH17447.1 - 6.3 6.7 44.4 0.74 9.8 25.2 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) HNF-1_N PF04814.13 CEH17447.1 - 7.1 7.2 17.6 1.3 9.6 6.2 2.1 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus UBA2_C PF16195.5 CEH17448.1 - 0.096 13.4 3.5 0.2 12.3 3.5 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus HA2 PF04408.23 CEH17449.1 - 6.6e-15 55.3 0.7 3.2e-14 53.1 0.1 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CEH17449.1 - 8.4e-13 48.6 0.0 2.2e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEH17449.1 - 6.9e-12 45.5 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 CEH17449.1 - 2.8e-11 43.6 0.0 7.8e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 CEH17449.1 - 0.00052 20.3 0.0 0.0018 18.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CEH17449.1 - 0.0019 17.3 0.0 0.0051 15.9 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 CEH17449.1 - 0.0024 17.9 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 CEH17449.1 - 0.042 13.4 0.1 4.5 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain LURAP PF14854.6 CEH17449.1 - 0.079 12.9 0.4 0.31 11.0 0.4 2.0 1 0 0 1 1 1 0 Leucine rich adaptor protein ATPase PF06745.13 CEH17449.1 - 0.093 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 CEH17449.1 - 0.11 12.9 0.0 0.35 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain tRNA_int_end_N2 PF12928.7 CEH17450.1 - 2.7e-15 56.3 0.6 1.4e-14 54.0 0.6 2.1 1 1 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 CEH17450.1 - 0.014 15.1 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain TPR_2 PF07719.17 CEH17451.1 - 2.1e-08 33.6 2.1 0.031 14.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEH17451.1 - 8.1e-07 28.6 0.9 0.17 11.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEH17451.1 - 2.5e-05 24.7 3.3 0.007 16.9 0.2 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEH17451.1 - 0.0031 18.2 2.5 2.4 9.2 0.4 3.1 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEH17451.1 - 0.004 17.8 2.6 0.18 12.5 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEH17451.1 - 0.025 14.6 0.3 6.1 7.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEH17451.1 - 0.092 13.1 2.0 4.2 7.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH17451.1 - 0.1 12.8 0.4 5.6 7.3 0.3 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CEH17451.1 - 0.12 12.6 0.1 6.1 7.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_B PF00136.21 CEH17452.1 - 3.8e-116 388.5 0.0 4.9e-116 388.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CEH17452.1 - 7.7e-53 179.0 5.7 1.5e-52 178.1 5.7 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 CEH17452.1 - 2e-23 83.1 0.0 3.5e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 CEH17452.1 - 3.6e-18 65.4 3.0 3.6e-18 65.4 3.0 2.3 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 CEH17452.1 - 0.066 12.1 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral YL1 PF05764.13 CEH17452.1 - 0.17 12.0 4.7 0.47 10.5 4.7 1.7 1 0 0 1 1 1 0 YL1 nuclear protein Tannase PF07519.11 CEH17453.1 - 4.4e-58 197.3 0.6 1.4e-45 156.1 0.0 3.3 3 0 0 3 3 3 3 Tannase and feruloyl esterase Esterase PF00756.20 CEH17453.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 CEH17453.1 - 0.085 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DHHA1 PF02272.19 CEH17453.1 - 0.29 11.6 3.4 0.97 9.8 3.4 1.9 1 0 0 1 1 1 0 DHHA1 domain LEAP-2 PF07359.11 CEH17454.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) HEPN_SAV_6107 PF18726.1 CEH17455.1 - 0.039 14.5 0.3 0.059 13.9 0.3 1.2 1 0 0 1 1 1 0 SAV_6107-like HEPN zf-CCCH PF00642.24 CEH17456.1 - 1.5e-09 37.5 2.7 2.5e-09 36.8 2.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEH17456.1 - 1.4e-05 25.0 4.4 2.3e-05 24.3 4.4 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CEH17456.1 - 0.0019 18.0 2.8 0.0028 17.4 2.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CEH17456.1 - 0.098 13.2 2.0 0.17 12.4 2.0 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_8 PF18633.1 CEH17456.1 - 9.1 6.5 7.1 1.1 9.4 1.5 2.3 3 0 0 3 3 3 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 ORC4_C PF14629.6 CEH17457.1 - 2.4e-33 115.3 0.1 4.9e-33 114.3 0.1 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 CEH17457.1 - 1e-09 39.0 0.5 1e-09 39.0 0.5 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CEH17457.1 - 0.026 14.8 0.4 0.41 10.9 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 CEH17457.1 - 0.03 13.8 0.1 0.056 12.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 CEH17457.1 - 0.051 13.6 0.1 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 CEH17457.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 CEH17457.1 - 0.11 12.9 0.1 3.9 7.9 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CEH17457.1 - 0.13 11.3 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 CEH17457.1 - 0.14 12.7 0.1 0.14 12.7 0.1 1.7 2 0 0 2 2 2 0 ABC transporter MCM PF00493.23 CEH17457.1 - 0.17 10.9 0.1 0.34 10.0 0.1 1.4 1 0 0 1 1 1 0 MCM P-loop domain Glyco_hydro_47 PF01532.20 CEH17459.1 - 4e-104 349.0 0.2 4.8e-104 348.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CBFD_NFYB_HMF PF00808.23 CEH17460.1 - 3e-16 59.5 0.4 3e-16 59.5 0.4 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YolD PF08863.10 CEH17460.1 - 0.03 14.4 0.7 0.06 13.4 0.7 1.5 1 0 0 1 1 1 0 YolD-like protein CENP-W PF15510.6 CEH17460.1 - 0.033 14.4 0.2 0.055 13.7 0.2 1.3 1 0 0 1 1 1 0 CENP-W protein DUF2767 PF10965.8 CEH17460.1 - 0.037 14.0 0.2 0.37 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2767) Aminotran_4 PF01063.19 CEH17461.1 - 2.9e-15 56.7 0.0 4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Steroid_dh PF02544.16 CEH17462.1 - 1.4e-16 60.8 0.0 2.5e-07 30.8 0.0 3.4 3 0 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase eRF1_1 PF03463.15 CEH17463.1 - 1.8e-48 163.8 0.0 2.6e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 CEH17463.1 - 5.7e-22 78.5 0.0 8.7e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CEH17463.1 - 1.6e-21 76.9 0.0 3.3e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 DASH_Spc34 PF08657.10 CEH17464.1 - 0.77 9.5 7.9 0.47 10.2 0.1 3.0 2 1 0 2 2 2 0 DASH complex subunit Spc34 Prominin PF05478.11 CEH17464.1 - 1.3 6.8 4.3 1.5 6.6 0.1 2.0 2 0 0 2 2 2 0 Prominin Ax_dynein_light PF10211.9 CEH17464.1 - 2.4 8.0 14.5 0.83 9.6 0.7 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4407 PF14362.6 CEH17464.1 - 4 6.7 14.1 7.4 5.8 14.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myosin_head PF00063.21 CEH17465.1 - 1.1e-226 754.3 0.0 1.3e-226 754.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CEH17465.1 - 1.2e-46 158.8 0.0 1.8e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 CEH17465.1 - 1.3e-10 41.0 0.2 2.8e-10 39.9 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEH17465.1 - 1.7e-10 40.4 0.6 3.2e-10 39.5 0.6 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEH17465.1 - 4e-06 26.4 0.0 9.3e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CEH17465.1 - 4.2e-05 23.7 0.5 9.3e-05 22.6 0.5 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Hpr_kinase_C PF07475.12 CEH17465.1 - 0.0071 15.9 0.2 0.51 9.8 0.0 2.4 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 CEH17465.1 - 0.0081 16.4 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEH17465.1 - 0.028 14.8 0.0 0.1 12.9 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain SH3_4 PF06347.13 CEH17465.1 - 0.029 14.2 0.2 0.07 13.0 0.2 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Sigma54_activat PF00158.26 CEH17465.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CEH17465.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.9 CEH17465.1 - 0.092 11.6 0.3 0.36 9.7 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Hexapep PF00132.24 CEH17466.1 - 3.3e-05 23.4 6.6 0.0013 18.4 2.1 3.4 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 CEH17466.1 - 0.009 14.2 0.3 0.034 12.3 0.3 1.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) Rhabdo_ncap PF00945.18 CEH17466.1 - 1.4 7.7 3.0 2.4 6.9 3.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Hexapep_2 PF14602.6 CEH17466.1 - 2.1 8.2 11.4 2.9 7.7 3.3 4.1 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase TIM PF00121.18 CEH17467.1 - 4.2e-90 301.4 0.1 4.7e-90 301.2 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 CEH17467.1 - 0.0025 17.3 0.1 0.009 15.5 0.1 1.8 1 1 1 2 2 2 1 CutC family zf-C2H2 PF00096.26 CEH17468.1 - 5.8e-23 80.0 29.3 6.1e-06 26.4 1.1 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEH17468.1 - 4.1e-19 68.1 26.6 3.3e-09 36.8 0.2 6.2 5 1 1 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEH17468.1 - 4.7e-08 33.2 26.3 0.02 15.7 0.8 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CEH17468.1 - 0.00087 19.5 6.0 0.0039 17.5 3.1 3.0 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 CEH17468.1 - 0.0031 17.2 0.1 0.0031 17.2 0.1 3.6 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CEH17468.1 - 0.012 15.9 6.5 0.63 10.4 0.1 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Pro_CA PF00484.19 CEH17469.1 - 5.6e-14 52.7 0.1 1.9e-13 51.0 0.1 1.8 1 1 0 1 1 1 1 Carbonic anhydrase RRM_1 PF00076.22 CEH17471.1 - 1.3e-08 34.5 0.0 2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase_fungal PF17667.1 CEH17472.1 - 1.6e-14 53.5 0.2 1.9e-09 36.8 0.0 3.7 3 1 0 3 3 3 2 Fungal protein kinase RPN7 PF10602.9 CEH17473.1 - 7e-41 139.8 0.1 1.4e-40 138.9 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CEH17473.1 - 1.3e-06 28.8 0.0 4.2e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.6 CEH17473.1 - 0.0097 16.2 4.2 0.28 11.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEH17473.1 - 0.029 14.5 0.4 3.5 8.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ST7 PF04184.12 CEH17473.1 - 0.058 11.8 0.0 0.083 11.3 0.0 1.2 1 0 0 1 1 1 0 ST7 protein TPR_1 PF00515.28 CEH17473.1 - 0.069 13.0 0.3 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 CEH17474.1 - 1.3e-31 108.1 25.8 1.2e-05 25.9 0.1 8.6 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH17474.1 - 1.6e-11 44.3 1.9 0.0085 16.4 0.1 5.2 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 CEH17474.1 - 1.4e-08 34.5 0.0 3.6e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 CEH17474.1 - 1.2e-05 24.2 1.8 0.47 9.0 0.0 5.0 4 1 1 5 5 5 1 Nucleoporin Nup120/160 WD40_like PF17005.5 CEH17474.1 - 2.8e-05 23.6 0.1 0.21 10.9 0.0 3.1 2 1 1 3 3 3 2 WD40-like domain PQQ_3 PF13570.6 CEH17474.1 - 0.014 15.9 2.3 1.1 9.8 0.1 4.0 3 1 0 3 3 3 0 PQQ-like domain F-box PF00646.33 CEH17474.1 - 0.02 14.8 0.1 0.05 13.5 0.1 1.7 1 0 0 1 1 1 0 F-box domain DUF3235 PF11574.8 CEH17474.1 - 2 9.4 13.5 0.12 13.2 0.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) FmiP_Thoc5 PF09766.9 CEH17475.1 - 3e-28 99.2 10.7 4.2e-28 98.7 10.7 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Spc7 PF08317.11 CEH17475.1 - 0.77 8.6 15.7 0.1 11.4 1.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 CEH17475.1 - 1 9.2 5.5 2.3 8.1 0.3 2.7 2 1 0 2 2 2 0 Septum formation initiator DUF2203 PF09969.9 CEH17475.1 - 1.1 10.0 8.0 0.19 12.5 0.9 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 CEH17475.1 - 1.2 9.6 17.2 0.18 12.4 3.0 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region BRCA-2_OB1 PF09103.10 CEH17476.1 - 5.9e-29 100.5 0.0 1.1e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 CEH17476.1 - 1.7e-08 34.4 0.3 3.7e-08 33.3 0.3 1.5 1 0 0 1 1 1 1 BRCA2, helical DTHCT PF08070.11 CEH17476.1 - 0.03 15.1 0.5 0.03 15.1 0.5 3.8 3 1 1 4 4 4 0 DTHCT (NUC029) region SNase PF00565.17 CEH17477.1 - 3.1e-49 166.0 1.0 2e-19 70.1 0.0 6.5 6 1 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 CEH17477.1 - 1e-15 57.9 0.0 2.3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 CEH17477.1 - 0.0034 17.8 0.0 1.8 9.1 0.0 2.8 2 0 0 2 2 2 2 Agenet domain Kin17_mid PF10357.9 CEH17478.1 - 3.1e-46 156.4 1.4 3.1e-46 156.4 1.4 1.6 2 1 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 CEH17478.1 - 3.8e-06 27.0 2.7 3.8e-06 27.0 2.7 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEH17478.1 - 0.0011 19.2 2.7 0.0027 18.1 2.7 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CEH17478.1 - 0.0041 17.4 0.9 0.04 14.3 0.1 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) K_oxygenase PF13434.6 CEH17478.1 - 0.011 14.9 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Cdc6_C PF09079.11 CEH17478.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain zf-C2H2_4 PF13894.6 CEH17478.1 - 0.094 13.6 1.5 0.16 12.9 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger AKAP95 PF04988.12 CEH17478.1 - 0.16 12.2 2.2 0.12 12.6 0.7 1.6 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 CEH17478.1 - 0.18 12.3 2.4 0.25 11.9 1.2 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-DBF PF07535.12 CEH17478.1 - 1.1 9.4 6.3 1.3 9.2 0.5 2.5 2 0 0 2 2 2 0 DBF zinc finger HA2 PF04408.23 CEH17479.1 - 1.9e-18 66.7 0.0 5.7e-18 65.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEH17479.1 - 2.6e-15 56.5 0.0 6.4e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEH17479.1 - 3.4e-13 49.9 0.0 9.9e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEH17479.1 - 6.5e-07 29.3 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEH17479.1 - 0.0001 22.6 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH17479.1 - 0.00055 20.3 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CEH17479.1 - 0.019 14.1 0.1 0.047 12.8 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 CEH17479.1 - 0.035 14.2 0.1 1.5 8.9 0.1 2.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CEH17479.1 - 0.076 12.5 0.0 0.59 9.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.6 CEH17479.1 - 0.079 13.5 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Alk_phosphatase PF00245.20 CEH17480.1 - 1.8e-88 297.3 0.1 2.4e-88 296.9 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Malt_amylase_C PF16657.5 CEH17481.1 - 0.017 15.3 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Alpha-amylase PF00128.24 CEH17482.1 - 3.1e-108 362.3 0.1 3.9e-108 362.0 0.1 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 CEH17482.1 - 0.0058 15.8 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Pkinase PF00069.25 CEH17483.1 - 3.1e-45 154.6 0.0 2.2e-44 151.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17483.1 - 1.5e-27 96.6 0.0 7.5e-27 94.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CEH17483.1 - 0.035 13.5 0.3 0.062 12.6 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEH17483.1 - 0.099 11.9 0.1 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like PH_4 PF15404.6 CEH17484.1 - 1.3e-39 135.9 0.0 2.9e-39 134.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CEH17484.1 - 0.087 13.3 0.0 1.2e+02 3.3 0.0 4.5 5 0 0 5 5 5 0 PH domain SKG6 PF08693.10 CEH17486.1 - 0.0045 16.4 0.2 0.008 15.6 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Eno-Rase_NADH_b PF12242.8 CEH17486.1 - 0.0051 16.5 0.2 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FGGY_N PF00370.21 CEH17487.1 - 0.0093 15.6 0.0 0.024 14.2 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain Pheromone PF08015.11 CEH17488.1 - 5.2 8.2 10.7 24 6.1 10.1 2.5 1 1 0 1 1 1 0 Fungal mating-type pheromone NADH-u_ox-rdase PF10785.9 CEH17489.1 - 7.2e-31 106.7 0.2 9.6e-31 106.3 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 CEH17489.1 - 4e-11 42.7 0.1 5.9e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Aminotran_1_2 PF00155.21 CEH17490.1 - 5.1e-40 137.7 0.0 9.2e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEH17490.1 - 0.018 13.6 0.0 0.036 12.6 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme ATG11 PF10377.9 CEH17491.1 - 3e-32 111.4 0.1 1e-31 109.6 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.12 CEH17491.1 - 6.5e-05 22.2 0.2 6.5e-05 22.2 0.2 4.8 4 1 1 5 5 5 2 Autophagy protein Apg17 DUF758 PF05527.11 CEH17491.1 - 0.33 10.9 1.4 0.56 10.2 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF758) Epimerase PF01370.21 CEH17492.1 - 0.0032 17.0 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family CagS PF16707.5 CEH17493.1 - 0.084 12.9 0.0 0.1 12.6 0.0 1.0 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori FMO-like PF00743.19 CEH17494.1 - 1.1e-26 93.3 0.0 6.3e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CEH17494.1 - 4.6e-14 52.3 0.0 2e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEH17494.1 - 2.4e-11 43.5 0.0 2e-07 30.6 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEH17494.1 - 4.9e-08 33.1 0.0 1.2e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CEH17494.1 - 3.1e-06 26.7 0.0 6e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 CEH17494.1 - 5.3e-06 25.8 0.8 3e-05 23.3 0.1 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CEH17494.1 - 8e-06 25.7 1.9 0.0001 22.0 0.9 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEH17494.1 - 0.00012 22.1 0.1 0.00065 19.7 0.1 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CEH17494.1 - 0.00013 22.5 0.9 0.0021 18.6 0.2 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 CEH17494.1 - 0.0041 16.7 0.2 0.0087 15.7 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 CEH17494.1 - 0.0052 16.1 0.0 0.009 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CEH17494.1 - 0.0058 15.9 0.0 0.046 13.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family IlvN PF07991.12 CEH17494.1 - 0.027 14.0 0.1 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_2 PF00890.24 CEH17494.1 - 0.028 13.5 0.2 0.17 10.9 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 CEH17494.1 - 0.029 13.7 0.1 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CEH17494.1 - 0.044 14.2 0.0 17 5.9 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 CEH17494.1 - 0.055 12.8 0.2 0.7 9.2 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AT_hook PF02178.19 CEH17495.1 - 0.2 11.6 15.1 0.65 10.1 4.2 3.4 2 0 0 2 2 2 0 AT hook motif RRM_1 PF00076.22 CEH17497.1 - 0.00046 20.0 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 CEH17497.1 - 0.062 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-CHC2 PF01807.20 CEH17498.1 - 0.11 12.3 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 CHC2 zinc finger Gar1 PF04410.14 CEH17499.1 - 1.1e-30 106.4 1.1 5.6e-29 100.9 0.0 3.1 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region BTB_2 PF02214.22 CEH17499.1 - 0.0011 19.3 0.0 0.0052 17.1 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Macoilin PF09726.9 CEH17499.1 - 2.9 6.4 12.9 1.4 7.4 10.6 1.7 2 0 0 2 2 2 0 Macoilin family TRAM_LAG1_CLN8 PF03798.16 CEH17500.1 - 9.6e-34 116.9 29.2 9.6e-34 116.9 29.2 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CEH17500.1 - 2.2e-20 72.1 0.0 2.2e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein Abhydrolase_6 PF12697.7 CEH17502.1 - 1.7e-19 71.3 0.8 5.3e-19 69.7 0.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEH17502.1 - 8.4e-16 58.4 0.1 2.7e-12 46.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH17502.1 - 6.7e-07 28.8 0.0 1.5e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 CEH17502.1 - 0.003 17.7 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 CEH17502.1 - 0.047 13.2 0.0 0.16 11.4 0.0 1.8 2 1 1 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CEH17502.1 - 0.14 12.0 0.0 22 4.7 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Cu_amine_oxid PF01179.20 CEH17503.1 - 5.7e-151 503.1 0.1 8e-123 410.4 0.0 2.0 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 CEH17503.1 - 5.7e-13 49.1 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Mannosyl_trans PF05007.13 CEH17504.1 - 3.2e-52 178.0 9.0 3.2e-52 178.0 9.0 2.3 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CEH17504.1 - 1.3e-09 37.7 3.1 0.0033 16.5 0.0 3.4 2 1 1 3 3 3 3 GPI transamidase subunit PIG-U Pro_dh PF01619.18 CEH17505.1 - 1.8e-57 195.1 0.0 3e-25 89.4 0.1 3.2 2 1 1 3 3 3 3 Proline dehydrogenase Spore_YpjB PF09577.10 CEH17505.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) FGGY_C PF02782.16 CEH17506.1 - 1.3e-43 149.0 0.1 1.3e-43 149.0 0.1 2.0 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CEH17506.1 - 3.2e-17 62.9 0.8 2.1e-09 37.3 0.0 3.1 3 0 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 CEH17506.1 - 0.0011 18.5 0.1 0.027 14.0 0.0 2.3 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Phage_GPL PF05926.11 CEH17506.1 - 0.55 10.2 5.2 6.6 6.7 0.4 2.9 3 0 0 3 3 3 0 Phage head completion protein (GPL) Methyltransf_33 PF10017.9 CEH17507.1 - 1.9e-59 201.3 0.0 3.1e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 CEH17507.1 - 2.5e-10 40.4 0.0 9.4e-09 35.2 0.0 2.3 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 CEH17507.1 - 0.0014 19.1 0.1 0.044 14.3 0.0 2.7 1 1 1 2 2 2 2 DinB superfamily SF1-HH PF16275.5 CEH17510.1 - 6.7e-37 126.3 0.9 1.8e-36 124.9 0.1 2.0 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 CEH17510.1 - 3.1e-09 36.5 13.3 1.8e-05 24.6 2.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CEH17510.1 - 1.9e-05 24.5 11.3 0.0033 17.4 3.7 2.4 1 1 1 2 2 2 2 Zinc knuckle DUF1897 PF09005.10 CEH17510.1 - 3.1e-05 23.4 9.3 3.1e-05 23.4 9.3 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1897) KH_1 PF00013.29 CEH17510.1 - 3.3e-05 23.6 0.6 8.1e-05 22.4 0.6 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_2 PF13696.6 CEH17510.1 - 0.0025 17.6 14.4 0.17 11.7 3.8 2.5 2 0 0 2 2 2 2 Zinc knuckle WD40 PF00400.32 CEH17511.1 - 2.5e-11 44.0 16.8 0.00038 21.2 0.4 6.1 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH17511.1 - 3e-09 37.1 0.0 0.0023 18.2 0.0 3.9 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 CEH17511.1 - 0.0083 14.9 0.5 1.2 7.8 0.3 2.9 2 1 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 CEH17511.1 - 0.038 13.9 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat CsbD PF05532.12 CEH17512.1 - 1.5e-15 56.8 18.1 7.5e-10 38.6 6.8 2.0 1 1 1 2 2 2 2 CsbD-like Alanine_zipper PF11839.8 CEH17512.1 - 0.012 16.0 6.6 0.65 10.4 0.6 2.2 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Gp5_C PF06715.12 CEH17512.1 - 0.24 11.6 4.6 2.9 8.2 0.2 3.1 3 1 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) Pkinase PF00069.25 CEH17513.1 - 1.4e-21 77.1 0.0 1e-09 38.2 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17513.1 - 3.1e-08 33.2 0.0 0.00088 18.6 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Fungal_trans PF04082.18 CEH17514.1 - 4e-10 39.2 0.1 7.3e-10 38.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH17514.1 - 1.9e-05 24.7 8.3 3.9e-05 23.7 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 CEH17514.1 - 0.19 12.1 4.0 0.51 10.7 4.0 1.7 1 0 0 1 1 1 0 Opy2 protein HrpB7 PF09486.10 CEH17515.1 - 0.0021 18.4 15.5 0.0021 18.4 15.5 8.0 2 1 4 7 7 7 1 Bacterial type III secretion protein (HrpB7) ADH_zinc_N PF00107.26 CEH17516.1 - 1.4e-11 44.5 0.1 3.4e-11 43.2 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH17516.1 - 4.2e-08 33.0 0.0 7.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CEH17516.1 - 0.011 16.8 0.0 0.019 16.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase IPT PF01745.16 CEH17516.1 - 0.22 10.9 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Isopentenyl transferase AAA PF00004.29 CEH17517.1 - 7.7e-39 133.1 0.0 1.2e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEH17517.1 - 5.2e-09 35.8 0.0 1.6e-08 34.2 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 CEH17517.1 - 1.7e-06 27.9 0.0 5.1e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEH17517.1 - 3.1e-05 24.0 0.1 0.00012 22.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEH17517.1 - 4e-05 24.1 0.3 0.0011 19.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 CEH17517.1 - 5.5e-05 22.7 0.3 0.0025 17.2 0.3 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CEH17517.1 - 6e-05 23.3 0.3 0.0019 18.5 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEH17517.1 - 6.1e-05 23.6 0.0 0.0011 19.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CEH17517.1 - 0.00013 22.2 0.0 0.00025 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CEH17517.1 - 0.00021 21.5 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEH17517.1 - 0.00026 21.0 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CEH17517.1 - 0.00052 19.3 0.2 0.0047 16.2 0.1 2.3 2 1 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 CEH17517.1 - 0.00056 19.7 0.0 0.00095 18.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 CEH17517.1 - 0.0012 18.9 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 CEH17517.1 - 0.0024 17.4 0.1 0.013 15.1 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 CEH17517.1 - 0.0032 17.7 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CEH17517.1 - 0.0064 16.1 0.4 0.085 12.4 0.4 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CEH17517.1 - 0.009 15.7 0.2 0.023 14.5 0.3 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CEH17517.1 - 0.0097 16.3 0.0 0.026 14.9 0.0 1.7 1 1 1 2 2 1 1 RNA helicase Sigma54_activat PF00158.26 CEH17517.1 - 0.01 15.5 0.1 0.052 13.3 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain TniB PF05621.11 CEH17517.1 - 0.014 14.9 0.0 2.3 7.6 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein Guanylate_kin PF00625.21 CEH17517.1 - 0.018 14.7 0.0 0.055 13.1 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase DUF815 PF05673.13 CEH17517.1 - 0.03 13.5 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 CEH17517.1 - 0.037 14.5 0.5 0.099 13.1 0.1 1.9 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 CEH17517.1 - 0.038 14.0 0.1 0.071 13.1 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CEH17517.1 - 0.04 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Rad17 PF03215.15 CEH17517.1 - 0.041 13.8 0.0 0.094 12.6 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain HIGH_NTase1_ass PF16581.5 CEH17517.1 - 0.046 13.7 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region NACHT PF05729.12 CEH17517.1 - 0.048 13.6 0.2 0.17 11.8 0.1 2.0 2 0 0 2 2 1 0 NACHT domain IPT PF01745.16 CEH17517.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase CPT PF07931.12 CEH17517.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 CEH17517.1 - 0.082 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Bac_DnaA PF00308.18 CEH17517.1 - 0.096 12.5 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.27 CEH17517.1 - 0.1 13.1 0.2 0.24 11.9 0.0 1.7 2 0 0 2 2 1 0 ABC transporter AAA_3 PF07726.11 CEH17517.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CEH17517.1 - 0.16 11.2 0.3 0.27 10.5 0.3 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 CEH17517.1 - 0.18 11.5 0.5 0.62 9.7 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 CEH17517.1 - 0.21 10.5 0.1 0.31 9.9 0.1 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region C2 PF00168.30 CEH17519.1 - 1.3e-68 227.8 0.1 2.5e-18 66.3 0.0 4.5 4 0 0 4 4 4 4 C2 domain NT-C2 PF10358.9 CEH17519.1 - 0.00012 21.9 0.1 0.054 13.2 0.0 3.3 3 0 0 3 3 3 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ras PF00071.22 CEH17520.1 - 1.8e-54 183.7 0.0 2.1e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH17520.1 - 1.2e-20 73.9 0.0 1.8e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH17520.1 - 5.3e-07 29.2 0.0 5.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEH17520.1 - 0.0006 19.4 0.1 0.0048 16.5 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEH17520.1 - 0.0024 17.8 0.1 0.81 9.6 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CEH17520.1 - 0.0039 16.6 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CEH17520.1 - 0.0043 16.6 0.2 0.026 14.1 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 CEH17520.1 - 0.0078 15.7 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CEH17520.1 - 0.087 13.2 0.1 0.18 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 CEH17520.1 - 0.11 12.5 0.3 0.22 11.6 0.3 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 CEH17520.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ion_trans_2 PF07885.16 CEH17523.1 - 2.3e-26 91.6 25.8 9e-14 51.2 2.5 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CEH17523.1 - 0.0042 16.3 6.4 0.0042 16.3 6.4 2.7 2 1 0 2 2 2 1 Ion transport protein Ank_4 PF13637.6 CEH17524.1 - 2.4e-10 40.7 0.4 6.7e-05 23.4 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEH17524.1 - 3.7e-08 33.0 1.3 0.035 14.7 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 CEH17524.1 - 1.5e-06 28.7 1.9 0.0057 17.2 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEH17524.1 - 1.8e-05 24.9 4.9 0.0091 16.3 0.7 3.4 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CEH17524.1 - 0.00018 21.8 5.4 0.41 11.2 0.8 4.0 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 CEH17524.1 - 0.0047 16.8 0.2 0.074 12.9 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain FMO-like PF00743.19 CEH17525.1 - 1.1e-13 50.4 0.1 8.8e-12 44.2 0.1 2.8 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CEH17525.1 - 3.6e-10 39.6 0.0 6.6e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEH17525.1 - 6.5e-09 35.4 0.0 5.8e-07 29.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CEH17525.1 - 5e-08 32.6 0.5 0.0019 17.5 0.0 2.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEH17525.1 - 1.8e-06 28.0 0.0 3.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEH17525.1 - 0.00015 21.5 0.0 0.015 14.9 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEH17525.1 - 0.00066 19.7 0.7 0.24 11.4 0.2 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CEH17525.1 - 0.00077 20.0 0.0 0.14 12.7 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CEH17525.1 - 0.0016 18.5 0.1 0.1 12.7 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 CEH17525.1 - 0.11 11.7 0.2 0.26 10.5 0.1 1.5 2 0 0 2 2 2 0 Thi4 family CRISPR_Cse1 PF09481.10 CEH17525.1 - 0.12 11.4 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) MFS_1 PF07690.16 CEH17526.1 - 2.1e-37 128.9 36.6 1.8e-33 116.0 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH17526.1 - 7.4e-24 84.4 13.2 2.2e-22 79.6 13.2 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter SLX9 PF15341.6 CEH17528.1 - 3.4e-12 46.9 7.9 3.4e-12 46.9 7.9 1.6 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 HA2 PF04408.23 CEH17529.1 - 3.1e-22 78.9 0.7 1.5e-21 76.7 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEH17529.1 - 2e-13 50.5 0.0 4.1e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEH17529.1 - 2.9e-10 40.5 0.0 1.5e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEH17529.1 - 3e-05 23.9 0.0 0.00022 21.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEH17529.1 - 0.00018 21.8 0.0 0.00074 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CEH17529.1 - 0.032 13.6 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 CEH17529.1 - 0.048 14.2 0.1 0.93 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CEH17529.1 - 0.12 11.4 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein SMP PF04927.12 CEH17529.1 - 3.1 8.3 8.2 0.28 11.7 1.2 2.9 2 0 0 2 2 2 0 Seed maturation protein zf-H2C2_2 PF13465.6 CEH17530.1 - 0.00079 19.7 2.6 0.28 11.7 0.3 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-Di19 PF05605.12 CEH17530.1 - 0.0085 16.4 2.4 0.0085 16.4 2.4 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CEH17530.1 - 0.0099 16.3 0.3 0.0099 16.3 0.3 3.3 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf_Hakai PF18408.1 CEH17530.1 - 0.055 13.2 0.2 0.18 11.6 0.2 1.9 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain zf-C2H2_12 PF18658.1 CEH17530.1 - 0.097 12.3 6.1 1.4 8.5 2.1 2.9 1 1 1 2 2 2 0 Zinc-finger C2H2-type FYDLN_acid PF09538.10 CEH17530.1 - 0.14 12.9 0.8 0.37 11.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_4 PF13894.6 CEH17530.1 - 0.2 12.6 8.3 0.57 11.2 0.2 3.7 2 1 0 2 2 2 0 C2H2-type zinc finger GAGA PF09237.11 CEH17530.1 - 0.21 11.4 6.7 0.099 12.5 4.2 1.8 1 1 0 1 1 1 0 GAGA factor Ofd1_CTDD PF10637.9 CEH17531.1 - 4.9e-82 275.1 0.0 2.4e-77 259.8 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CEH17531.1 - 9.2e-30 103.2 0.0 4.1e-29 101.1 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CEH17531.1 - 1.2e-14 55.0 0.0 2.5e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily His_Phos_1 PF00300.22 CEH17531.1 - 1.6e-10 41.0 1.3 2.7e-09 37.0 0.7 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 2OG-FeII_Oxy PF03171.20 CEH17531.1 - 0.053 14.0 0.0 0.26 11.8 0.0 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Septin PF00735.18 CEH17532.1 - 2e-27 96.2 0.0 1.3e-07 31.2 0.0 4.8 5 0 0 5 5 5 4 Septin AAA_16 PF13191.6 CEH17532.1 - 0.00016 22.1 0.1 0.0005 20.5 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CEH17532.1 - 0.00049 19.5 0.0 0.00087 18.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.6 CEH17532.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CEH17532.1 - 0.025 13.8 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 CEH17532.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CEH17532.1 - 0.094 11.9 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CEH17532.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain PPR_2 PF13041.6 CEH17533.1 - 0.0038 17.4 0.0 0.6 10.3 0.0 2.9 2 0 0 2 2 2 2 PPR repeat family RXT2_N PF08595.11 CEH17534.1 - 0.017 15.2 8.4 0.12 12.4 0.0 3.5 3 0 0 3 3 3 0 RXT2-like, N-terminal DUF1741 PF08427.10 CEH17535.1 - 1.4e-21 77.3 0.0 2.3e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) CBFD_NFYB_HMF PF00808.23 CEH17536.1 - 3.3e-15 56.1 0.1 5.4e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEH17536.1 - 1.2e-07 32.2 0.5 4.2e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Peptidase_S10 PF00450.22 CEH17537.1 - 1.5e-70 238.7 0.0 2e-70 238.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase UDPG_MGDP_dh_N PF03721.14 CEH17538.1 - 3.7e-55 186.4 0.0 1.6e-54 184.3 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 CEH17538.1 - 5.9e-36 123.1 0.0 6.3e-35 119.8 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 CEH17538.1 - 4.7e-32 110.1 0.0 8.7e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain COA2 PF17051.5 CEH17539.1 - 0.011 15.7 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 ELFV_dehydrog PF00208.21 CEH17540.1 - 9.1e-73 244.9 0.6 1.2e-72 244.5 0.6 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CEH17540.1 - 4.2e-46 156.0 0.0 9e-46 155.0 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 CEH17540.1 - 0.034 14.6 0.1 0.1 13.1 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF2255 PF10012.9 CEH17540.1 - 0.14 12.3 0.0 1 9.5 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2255) Pkinase PF00069.25 CEH17541.1 - 1.5e-66 224.5 0.0 2.1e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17541.1 - 1.4e-47 162.2 0.0 2e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH17541.1 - 1e-08 34.8 0.0 1.7e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CEH17541.1 - 0.0016 17.8 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH17541.1 - 0.0022 17.9 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ras_bdg_2 PF14847.6 CEH17541.1 - 0.0038 17.5 0.0 0.0074 16.6 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Haspin_kinase PF12330.8 CEH17541.1 - 0.076 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CEH17541.1 - 0.11 11.6 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PD40 PF07676.12 CEH17541.1 - 0.14 12.1 2.7 0.98 9.4 0.1 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PCI PF01399.27 CEH17543.1 - 6.4e-17 62.0 0.0 2.7e-16 60.0 0.0 2.1 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 CEH17543.1 - 4.9e-12 45.7 0.5 1e-11 44.7 0.5 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Paf67 PF10255.9 CEH17543.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 CSN8_PSD8_EIF3K PF10075.9 CEH17543.1 - 0.06 13.3 0.0 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family TPR_16 PF13432.6 CEH17543.1 - 0.094 13.4 0.4 5.9 7.6 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3579 PF12112.8 CEH17545.1 - 0.0064 17.0 0.0 0.0088 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3579) Mito_carr PF00153.27 CEH17546.1 - 6.7e-56 186.2 0.5 2.6e-20 72.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GST_N PF02798.20 CEH17547.1 - 0.00015 22.1 0.0 0.00061 20.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEH17547.1 - 0.027 14.8 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF1917 PF08939.10 CEH17548.1 - 1.4e-13 51.3 0.0 2.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Xan_ur_permease PF00860.20 CEH17549.1 - 4.1e-51 173.9 31.3 1.3e-49 168.9 31.3 2.1 1 1 0 1 1 1 1 Permease family Phage_holin_2_3 PF16080.5 CEH17549.1 - 9.3 6.1 11.9 0.46 10.3 1.4 3.4 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Nramp PF01566.18 CEH17550.1 - 4.9e-85 285.6 28.4 3.5e-38 131.5 8.8 3.0 3 0 0 3 3 3 3 Natural resistance-associated macrophage protein Abhydrolase_1 PF00561.20 CEH17552.1 - 1.3e-22 80.7 0.1 1.7e-22 80.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH17552.1 - 8.5e-13 49.4 8.3 1.1e-12 49.1 8.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH17552.1 - 1.7e-09 37.4 0.2 2.4e-09 36.8 0.2 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CEH17552.1 - 0.012 15.8 0.0 2.1 8.4 0.0 2.7 2 1 0 2 2 2 0 Thioesterase domain Ndr PF03096.14 CEH17552.1 - 0.021 13.6 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Ndr family DUF3530 PF12048.8 CEH17552.1 - 0.13 11.7 0.0 0.34 10.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) Rep_fac_C PF08542.11 CEH17553.1 - 1.2e-27 96.1 0.0 2.4e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 CEH17553.1 - 3.6e-12 46.9 0.0 6.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CEH17553.1 - 1.2e-11 44.6 0.0 6.9e-10 38.9 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 CEH17553.1 - 9.6e-07 28.9 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEH17553.1 - 1.4e-06 28.8 0.0 0.00013 22.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 CEH17553.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEH17553.1 - 1.7e-05 25.1 0.0 0.021 15.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 CEH17553.1 - 0.00024 20.9 0.0 0.00062 19.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CEH17553.1 - 0.00063 19.7 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 CEH17553.1 - 0.0025 17.6 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.13 CEH17553.1 - 0.006 16.4 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 CEH17553.1 - 0.0074 15.7 0.0 0.081 12.3 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 CEH17553.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CEH17553.1 - 0.016 15.2 0.0 0.044 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 CEH17553.1 - 0.016 14.2 0.0 0.043 12.8 0.0 1.7 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CEH17553.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CEH17553.1 - 0.054 12.8 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 CEH17553.1 - 0.069 13.1 0.1 0.21 11.5 0.1 1.8 1 1 1 2 2 2 0 NTPase AAA_assoc_2 PF16193.5 CEH17553.1 - 0.098 13.0 0.0 0.56 10.6 0.0 2.2 3 0 0 3 3 3 0 AAA C-terminal domain AAA_19 PF13245.6 CEH17553.1 - 0.15 12.4 0.1 1.5 9.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.22 CEH17553.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain WD40 PF00400.32 CEH17554.1 - 8.6e-24 83.4 12.1 0.00045 21.0 0.1 7.1 5 2 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH17554.1 - 8.8e-09 35.5 0.7 0.037 14.3 0.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEH17554.1 - 0.0016 17.5 0.1 3.8 6.4 0.0 3.7 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CEH17554.1 - 0.0085 15.5 1.4 0.056 12.8 0.1 2.5 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal CbiG_N PF11760.8 CEH17554.1 - 0.039 14.0 0.6 1.2 9.2 0.2 2.5 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal DUF844 PF05815.11 CEH17555.1 - 0.11 11.7 3.3 0.39 9.9 0.9 2.0 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF844) DivIC PF04977.15 CEH17555.1 - 0.19 11.5 6.4 4.6 7.1 1.7 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF2232 PF09991.9 CEH17555.1 - 0.22 10.7 0.1 0.37 9.9 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) bZIP_1 PF00170.21 CEH17555.1 - 0.24 11.5 6.4 5.8 7.1 0.5 2.6 2 0 0 2 2 2 0 bZIP transcription factor SlyX PF04102.12 CEH17555.1 - 5.3 7.7 7.7 10 6.8 2.4 2.4 2 0 0 2 2 2 0 SlyX Aldedh PF00171.22 CEH17557.1 - 9.7e-177 588.1 0.3 1.1e-176 587.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 CEH17557.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family Aldo_ket_red PF00248.21 CEH17558.1 - 6.7e-63 212.6 0.0 7.6e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF5549 PF17703.1 CEH17561.1 - 0.045 13.4 0.1 1.8 8.2 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5549) GRDP-like PF07173.12 CEH17563.1 - 5e-16 59.6 0.5 1.2e-12 48.7 0.0 4.2 3 1 1 4 4 4 2 Glycine-rich domain-containing protein-like Corona_NS1 PF06145.11 CEH17563.1 - 0.015 14.8 0.1 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 Acyl-CoA_dh_1 PF00441.24 CEH17564.1 - 1.1e-43 149.1 1.1 1.1e-43 149.1 1.1 1.9 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEH17564.1 - 4.9e-27 94.8 0.9 2e-26 92.9 0.1 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CEH17564.1 - 1.1e-23 83.2 0.1 1.9e-23 82.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEH17564.1 - 5.2e-20 72.1 0.2 5.2e-20 72.1 0.2 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AgrD PF05931.11 CEH17564.1 - 0.029 14.4 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal AgrD protein DUF4698 PF15769.5 CEH17564.1 - 0.062 12.4 1.4 0.087 11.9 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) LPP PF04728.13 CEH17564.1 - 0.19 12.1 2.4 0.65 10.4 0.1 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Chromo PF00385.24 CEH17565.1 - 7.3e-05 22.6 0.1 0.00014 21.7 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FAM177 PF14774.6 CEH17565.1 - 0.067 13.6 0.3 0.17 12.3 0.2 1.7 1 1 0 1 1 1 0 FAM177 family Plasmodium_Vir PF05795.11 CEH17567.1 - 5.3 6.4 14.9 1.6 8.1 7.0 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Macoilin PF09726.9 CEH17567.1 - 5.6 5.4 23.8 4.1 5.8 4.2 2.3 2 0 0 2 2 2 0 Macoilin family DUF572 PF04502.13 CEH17567.1 - 9.1 5.8 17.8 16 5.0 10.9 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) SNARE PF05739.19 CEH17568.1 - 0.00088 19.2 0.7 0.0021 18.0 0.7 1.7 1 1 0 1 1 1 1 SNARE domain DUF384 PF04064.13 CEH17568.1 - 0.16 11.8 0.9 0.28 11.1 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF384) SWIRM PF04433.17 CEH17569.1 - 2.9e-05 24.3 0.0 7.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain DUF3306 PF11748.8 CEH17569.1 - 3.3 8.6 13.9 0.13 13.1 0.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3306) ZZ PF00569.17 CEH17570.1 - 5.3e-12 45.3 5.3 9.3e-12 44.6 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CEH17570.1 - 3.5e-10 39.9 0.0 6.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH17570.1 - 0.00029 21.0 0.0 0.0005 20.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 CEH17570.1 - 0.044 14.1 4.0 0.081 13.2 4.0 1.4 1 0 0 1 1 1 0 C1 domain Caskin-Pro-rich PF16907.5 CEH17570.1 - 0.9 10.1 5.0 0.35 11.4 2.0 1.8 2 0 0 2 2 2 0 Proline rich region of Caskin proteins OTCace_N PF02729.21 CEH17571.1 - 5.8e-46 156.2 0.0 1.1e-45 155.3 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 CEH17571.1 - 2.1e-45 154.6 0.0 2.9e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF4451 PF14616.6 CEH17572.1 - 3.4e-17 62.8 0.4 7.5e-16 58.4 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4451) HEAT_EZ PF13513.6 CEH17574.1 - 8.1e-30 102.9 14.0 7.5e-08 32.7 0.0 10.7 11 2 1 12 12 11 4 HEAT-like repeat HEAT PF02985.22 CEH17574.1 - 1.1e-17 62.5 21.5 0.0031 17.6 0.1 12.0 13 0 0 13 13 12 3 HEAT repeat HEAT_2 PF13646.6 CEH17574.1 - 8e-17 61.4 13.2 0.025 15.0 0.0 8.4 6 3 2 9 9 8 6 HEAT repeats UME PF08064.13 CEH17574.1 - 1.1e-12 47.7 0.0 0.18 11.7 0.0 6.4 5 2 1 6 6 6 4 UME (NUC010) domain Cnd1 PF12717.7 CEH17574.1 - 1.4e-11 44.7 1.6 0.0047 17.0 0.0 5.6 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 CEH17574.1 - 6.7e-08 32.3 0.0 2.3e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 CEH17574.1 - 2.8e-07 29.5 2.1 0.023 13.3 0.0 4.5 4 1 1 5 5 5 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 CEH17574.1 - 6.2e-07 29.9 0.0 3.5 8.3 0.0 5.5 5 1 1 6 6 5 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 CEH17574.1 - 6.5e-07 29.3 0.0 2.9 7.6 0.0 4.9 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis MMS19_N PF14500.6 CEH17574.1 - 4e-05 23.3 0.2 0.034 13.7 0.1 4.3 5 0 0 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 CEH17574.1 - 7.1e-05 22.1 0.0 6 5.9 0.1 5.4 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 CEH17574.1 - 0.00039 20.1 0.0 0.31 10.6 0.0 4.3 4 0 0 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 CEH17574.1 - 0.00047 20.3 3.3 9.3 6.5 0.0 5.9 6 1 1 7 7 6 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 CEH17574.1 - 0.00061 19.7 0.4 1.2 9.1 0.0 4.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) Cohesin_HEAT PF12765.7 CEH17574.1 - 0.00066 19.9 0.2 4.6 7.6 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Dopey_N PF04118.14 CEH17574.1 - 0.00066 18.9 0.0 1.1 8.3 0.0 3.7 2 1 1 3 3 3 2 Dopey, N-terminal CAS_CSE1 PF03378.15 CEH17574.1 - 0.0015 17.1 0.2 4.8 5.6 0.0 4.0 4 0 0 4 4 4 2 CAS/CSE protein, C-terminus DUF3385 PF11865.8 CEH17574.1 - 0.0016 18.4 1.1 4.8 7.1 0.0 5.3 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) Cnd3 PF12719.7 CEH17574.1 - 0.0025 17.0 5.0 0.88 8.7 0.6 4.5 5 1 0 5 5 5 1 Nuclear condensing complex subunits, C-term domain ParcG PF10274.9 CEH17574.1 - 0.011 15.8 0.0 0.25 11.5 0.0 2.9 1 1 1 2 2 2 0 Parkin co-regulated protein DUF2267 PF10025.9 CEH17574.1 - 0.042 14.1 0.9 0.82 10.0 0.3 3.2 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2267) Mon2_C PF16206.5 CEH17574.1 - 0.095 10.8 0.1 4 5.5 0.0 2.2 2 0 0 2 2 2 0 C-terminal region of Mon2 protein DUF3304 PF11745.8 CEH17574.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) adh_short PF00106.25 CEH17578.1 - 4.7e-11 42.5 0.7 1.2e-09 38.0 1.4 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH17578.1 - 4.1e-08 33.1 0.3 2e-07 30.8 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 CEH17578.1 - 0.001 19.0 0.3 0.0016 18.3 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 CEH17578.1 - 0.0023 17.8 0.4 0.0038 17.2 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 CEH17578.1 - 0.0033 17.6 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 CEH17578.1 - 0.035 13.5 0.1 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 CEH17578.1 - 0.14 12.8 0.3 0.24 12.0 0.3 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_1 PF00561.20 CEH17579.1 - 2.9e-18 66.4 0.0 8.7e-17 61.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEH17579.1 - 3.4e-18 65.8 0.0 1.2e-14 54.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEH17579.1 - 5.1e-14 53.4 1.9 5.1e-14 53.4 1.9 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CEH17579.1 - 2.2e-06 27.7 0.1 0.00048 20.1 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 CEH17579.1 - 1.1e-05 25.3 0.1 2.1e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 CEH17579.1 - 0.00016 21.4 0.0 0.0006 19.5 0.0 2.0 3 0 0 3 3 3 1 Lipid-droplet associated hydrolase BAAT_C PF08840.11 CEH17579.1 - 0.00024 21.1 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.7 CEH17579.1 - 0.0013 17.7 0.0 0.0081 15.1 0.0 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 CEH17579.1 - 0.0019 18.0 0.0 0.067 13.0 0.0 2.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 CEH17579.1 - 0.0019 18.1 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 Serine hydrolase DUF915 PF06028.11 CEH17579.1 - 0.005 16.2 0.0 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 CEH17579.1 - 0.014 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Chlorophyllase PF07224.11 CEH17579.1 - 0.023 13.7 0.0 0.15 11.0 0.0 2.0 1 1 0 1 1 1 0 Chlorophyllase PolyA_pol PF01743.20 CEH17580.1 - 5e-19 69.0 0.0 4.8e-18 65.8 0.0 2.3 2 1 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CEH17580.1 - 6.3e-06 25.9 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A BUD22 PF09073.10 CEH17581.1 - 0.054 12.8 0.6 0.05 13.0 0.6 1.1 1 0 0 1 1 1 0 BUD22 DA1-like PF12315.8 CEH17581.1 - 0.17 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein DA1 RTBV_P12 PF06361.11 CEH17581.1 - 2 8.9 5.3 0.45 10.9 1.5 1.8 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein PLDc_2 PF13091.6 CEH17582.1 - 2e-20 73.0 0.0 3.4e-08 33.5 0.0 3.3 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 CEH17582.1 - 7.9e-16 57.5 2.1 1.1e-07 31.8 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif Sugar_tr PF00083.24 CEH17583.1 - 1.6e-34 119.6 19.6 3.7e-18 65.6 8.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEH17583.1 - 6.6e-25 87.8 64.6 2.9e-20 72.5 39.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MASE2 PF05230.11 CEH17583.1 - 0.026 14.6 0.5 0.75 9.9 0.0 3.1 3 0 0 3 3 3 0 MASE2 domain ADH_N PF08240.12 CEH17585.1 - 1e-26 92.9 1.3 3.5e-26 91.2 1.3 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEH17585.1 - 2.3e-22 79.4 0.9 3.8e-22 78.6 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CEH17585.1 - 0.0075 15.6 1.9 0.013 14.8 1.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CEH17585.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CEH17585.1 - 0.077 12.6 0.2 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TAF4 PF05236.14 CEH17587.1 - 2.2e-28 99.8 14.2 2.2e-28 99.8 14.2 3.0 2 2 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Ndc1_Nup PF09531.10 CEH17587.1 - 0.24 10.0 16.6 0.52 8.9 16.6 1.7 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fungal_trans PF04082.18 CEH17588.1 - 2.4e-20 72.7 0.0 4.6e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH17588.1 - 4.9e-08 33.0 7.2 1.3e-07 31.7 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 CEH17589.1 - 1.5e-05 25.0 8.9 3.4e-05 23.9 8.9 1.6 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CEH17589.1 - 0.041 12.9 0.1 0.32 10.0 0.0 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain DEC-1_N PF04625.13 CEH17589.1 - 0.19 10.7 1.5 4.8 6.1 1.8 2.5 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DJ-1_PfpI PF01965.24 CEH17590.1 - 2.6e-14 53.4 0.0 5.8e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CEH17590.1 - 0.0052 16.5 0.0 0.052 13.2 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like DUF5380 PF17351.2 CEH17590.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5380) FA_desaturase PF00487.24 CEH17591.1 - 2e-24 86.8 19.2 5.8e-14 52.5 5.6 2.2 2 0 0 2 2 2 2 Fatty acid desaturase DUF3474 PF11960.8 CEH17591.1 - 3.2e-06 27.4 0.0 7.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FHA PF00498.26 CEH17592.1 - 3e-13 49.9 0.0 5.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 CEH17592.1 - 1e-10 41.1 12.7 1.7e-10 40.4 12.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CEH17592.1 - 2.5e-07 30.9 13.7 3.9e-07 30.3 13.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEH17592.1 - 0.0024 17.6 14.2 0.0039 17.0 14.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEH17592.1 - 0.0049 17.1 8.9 0.0095 16.2 8.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CEH17592.1 - 0.013 15.6 5.5 0.023 14.8 5.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CEH17592.1 - 0.017 15.0 13.0 0.027 14.4 13.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH17592.1 - 0.084 12.9 11.9 0.14 12.1 11.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEH17592.1 - 0.84 9.7 12.7 1.6 8.8 12.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 CEH17592.1 - 4 7.4 11.7 6.9 6.6 11.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CEH17592.1 - 4.2 7.1 9.6 7 6.3 9.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 CEH17592.1 - 5.8 6.9 8.6 10 6.1 8.6 1.4 1 0 0 1 1 1 0 PHD-finger AMP-binding PF00501.28 CEH17593.1 - 4.4e-87 292.4 0.0 5.6e-87 292.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEH17593.1 - 4.7e-12 46.7 0.1 1.6e-11 45.0 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ERG2_Sigma1R PF04622.12 CEH17594.1 - 1.3e-79 266.4 0.0 1.6e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein MBOAT_2 PF13813.6 CEH17595.1 - 1.3e-16 60.6 1.3 1.1e-14 54.4 0.2 3.1 2 1 0 2 2 2 2 Membrane bound O-acyl transferase family AA_permease PF00324.21 CEH17596.1 - 1.4e-108 363.5 37.2 1.8e-108 363.2 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEH17596.1 - 2.5e-23 82.6 40.6 3.7e-23 82.1 40.6 1.2 1 0 0 1 1 1 1 Amino acid permease Spore_YtrH PF14034.6 CEH17596.1 - 0.045 13.9 2.1 0.12 12.5 2.1 1.7 1 0 0 1 1 1 0 Sporulation protein YtrH Zn_clus PF00172.18 CEH17597.1 - 4.6e-07 29.8 10.5 1.9e-06 27.9 10.5 1.9 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF836 PF05768.14 CEH17599.1 - 6.9e-11 42.4 0.0 9.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DUF1223 PF06764.11 CEH17599.1 - 0.097 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) N2227 PF07942.12 CEH17600.1 - 1.9e-91 306.0 0.0 2.6e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein DNAP_B_exo_N PF08452.10 CEH17601.1 - 0.0031 16.9 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B exonuclease domain, N-terminal Aldedh PF00171.22 CEH17602.1 - 1.3e-155 518.4 0.3 1.5e-155 518.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CEH17602.1 - 0.14 11.5 0.0 12 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Pyridoxal_deC PF00282.19 CEH17603.1 - 1.3e-85 287.4 0.0 2.8e-85 286.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Complex1_LYR_2 PF13233.6 CEH17604.1 - 9.8e-11 42.3 0.3 2e-10 41.3 0.3 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Oberon_cc PF16312.5 CEH17604.1 - 0.32 10.9 5.3 0.44 10.5 3.4 2.1 2 1 0 2 2 2 0 Coiled-coil region of Oberon TFIID-31kDa PF02291.15 CEH17605.1 - 1.3e-34 118.9 0.0 1.9e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEH17605.1 - 0.00046 20.2 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated LAP1C PF05609.12 CEH17605.1 - 1.7 7.7 7.4 2.3 7.2 7.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 CEH17605.1 - 3.5 5.7 14.3 4.5 5.4 14.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 CEH17605.1 - 7.7 4.5 16.3 10 4.1 16.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 CEH17605.1 - 8.6 5.2 11.4 12 4.8 11.4 1.1 1 0 0 1 1 1 0 Paf1 Cript PF10235.9 CEH17606.1 - 3.1e-18 66.1 7.7 3.1e-18 66.1 7.7 2.1 2 1 0 2 2 2 1 Microtubule-associated protein CRIPT zinc_ribbon_15 PF17032.5 CEH17606.1 - 0.0037 18.0 0.4 0.0037 18.0 0.4 2.8 3 0 0 3 3 3 1 zinc-ribbon family DZR PF12773.7 CEH17606.1 - 0.15 12.1 11.4 0.2 11.7 6.0 2.6 1 1 1 2 2 2 0 Double zinc ribbon zf-dskA_traR PF01258.17 CEH17606.1 - 0.21 11.5 0.0 0.21 11.5 0.0 3.0 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger DUF2039 PF10217.9 CEH17606.1 - 1.2 9.6 11.3 0.35 11.2 5.7 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) C1_2 PF03107.16 CEH17606.1 - 2.2 8.6 11.3 2 8.8 6.7 2.7 2 1 0 2 2 2 0 C1 domain zinc_ribbon_2 PF13240.6 CEH17606.1 - 2.3 8.0 12.3 18 5.2 5.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain C1_1 PF00130.22 CEH17606.1 - 2.7 7.9 12.4 11 6.1 3.9 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NinF PF05810.12 CEH17606.1 - 2.7 7.9 5.0 5.7 6.9 0.6 2.3 2 0 0 2 2 2 0 NinF protein zf_UBZ PF18439.1 CEH17606.1 - 3 7.5 5.9 19 5.0 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C3HC4_3 PF13920.6 CEH17606.1 - 4.6 7.2 10.7 25 4.8 6.8 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.12 CEH17606.1 - 5.5 6.6 11.3 3.3e+02 0.9 0.1 3.1 2 1 0 2 2 2 0 TFIIB zinc-binding Peptidase_M24 PF00557.24 CEH17608.1 - 1e-46 159.3 0.0 1.7e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CEH17608.1 - 1.5e-39 134.5 0.0 2.5e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain ThiF PF00899.21 CEH17609.1 - 8.9e-57 192.2 0.0 1.3e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CEH17609.1 - 7.1e-06 26.1 0.8 4.7e-05 23.5 0.0 2.4 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Rhodanese PF00581.20 CEH17609.1 - 0.0043 17.5 0.0 0.024 15.1 0.0 2.3 2 1 0 2 2 2 1 Rhodanese-like domain NAD_binding_7 PF13241.6 CEH17609.1 - 0.0052 17.2 0.1 0.011 16.2 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CEH17609.1 - 0.035 14.4 1.8 0.11 12.7 0.7 2.4 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 CEH17609.1 - 0.065 12.5 0.1 0.098 11.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 CEH17609.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 60KD_IMP PF02096.20 CEH17611.1 - 2.9e-14 53.3 0.0 4.2e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_S4 PF00163.19 CEH17612.1 - 1.8e-12 48.0 0.8 2.6e-12 47.5 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 CEH17612.1 - 2.2e-07 30.5 0.1 4.1e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 S4 domain THDPS_N_2 PF14805.6 CEH17612.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal CoA_binding PF02629.19 CEH17613.1 - 3e-29 101.6 0.3 7.4e-29 100.3 0.0 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CEH17613.1 - 3.1e-21 75.8 0.0 5.1e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CEH17613.1 - 1.3e-08 34.7 0.0 2.9e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CEH17613.1 - 9.2e-05 22.9 0.0 0.00025 21.5 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 CEH17613.1 - 0.061 14.2 0.0 0.26 12.1 0.0 2.1 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold PIG-U PF06728.13 CEH17614.1 - 2.2e-86 290.3 19.4 2.7e-86 290.0 19.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Flavin_Reduct PF01613.18 CEH17614.1 - 0.006 16.6 1.0 0.006 16.6 1.0 1.6 2 0 0 2 2 2 1 Flavin reductase like domain Fun_ATP-synt_8 PF05933.13 CEH17614.1 - 1.2 9.3 6.1 1 9.6 2.1 2.8 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) SH3_1 PF00018.28 CEH17615.1 - 5.5e-15 54.7 0.2 7.9e-15 54.2 0.2 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEH17615.1 - 1.7e-10 40.6 0.2 2.5e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEH17615.1 - 1.1e-08 34.6 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 CEH17615.1 - 0.004 17.2 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 CEH17615.1 - 0.057 13.7 0.3 0.12 12.6 0.3 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain hSH3 PF14603.6 CEH17615.1 - 0.17 12.3 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain Cupin_8 PF13621.6 CEH17616.1 - 1.9e-16 60.6 0.0 3.6e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CEH17616.1 - 2.3e-13 50.6 0.2 9e-09 35.8 0.1 2.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase Acetyltransf_1 PF00583.25 CEH17617.1 - 7.2e-09 35.9 0.0 1.8e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEH17617.1 - 2.9e-07 30.5 0.0 5.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEH17617.1 - 4.1e-06 27.1 0.0 8.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CEH17617.1 - 0.0034 17.5 0.0 0.009 16.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEH17617.1 - 0.0069 16.3 0.0 0.016 15.2 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein pP_pnuc_1 PF18165.1 CEH17617.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease SCAMP PF04144.13 CEH17618.1 - 5.7e-47 160.3 9.7 6.7e-47 160.0 9.7 1.0 1 0 0 1 1 1 1 SCAMP family DUF4061 PF13270.6 CEH17618.1 - 0.023 15.0 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) DUF4200 PF13863.6 CEH17618.1 - 0.25 11.7 3.2 0.37 11.2 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Peptidase_S8 PF00082.22 CEH17620.1 - 3e-45 154.8 0.1 5.8e-45 153.8 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Raffinose_syn PF05691.12 CEH17621.1 - 9.9e-05 20.3 0.0 0.0083 14.0 0.0 2.3 2 0 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 His_Phos_2 PF00328.22 CEH17624.1 - 9.1e-20 71.3 0.0 1.5e-18 67.4 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ING PF12998.7 CEH17626.1 - 2.6e-10 40.8 0.0 3.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CEH17626.1 - 6.9e-05 22.7 8.9 0.00011 22.0 8.9 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CEH17626.1 - 0.039 14.2 1.3 0.071 13.4 1.3 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 CEH17626.1 - 0.084 12.4 3.3 0.15 11.6 3.3 1.4 1 0 0 1 1 1 0 PHD-finger Abhydrolase_1 PF00561.20 CEH17627.1 - 1e-16 61.3 0.3 2e-15 57.1 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH17627.1 - 9.2e-16 59.1 0.0 1.4e-15 58.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH17627.1 - 8.6e-11 41.6 0.1 1.9e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CEH17627.1 - 2.8e-07 30.5 0.1 7e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 CEH17627.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 CEH17627.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 CEH17627.1 - 0.0024 18.0 0.0 0.0037 17.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 CEH17627.1 - 0.0029 16.5 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 CEH17627.1 - 0.01 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.13 CEH17627.1 - 0.029 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 CEH17627.1 - 0.068 11.7 0.2 3.4 6.1 0.1 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF3089 PF11288.8 CEH17627.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lipase_3 PF01764.25 CEH17627.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 CEH17627.1 - 0.15 11.6 0.0 0.9 9.0 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family OmdA PF13376.6 CEH17628.1 - 7.3e-14 51.5 0.7 1.8e-13 50.3 0.7 1.7 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated CRAL_TRIO PF00650.20 CEH17629.1 - 2.2e-25 89.2 0.0 3.3e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEH17629.1 - 7.5e-07 29.2 0.1 1.6e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF3544 PF12064.8 CEH17629.1 - 3.6 7.8 9.7 0.49 10.6 5.5 1.6 2 0 0 2 2 2 0 Protein kinase C-binding protein 1 WD40 PF00400.32 CEH17630.1 - 1.9e-19 69.6 10.1 5.5e-07 30.2 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 CEH17630.1 - 4.5e-05 22.3 0.1 0.52 8.9 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CEH17630.1 - 4.5e-05 23.7 0.0 0.26 11.6 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEH17630.1 - 0.0088 15.0 0.0 0.53 9.2 0.0 2.7 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NUDE_C PF04880.13 CEH17631.1 - 1.2e-13 52.0 8.1 1.2e-13 52.0 8.1 5.2 2 2 4 6 6 6 1 NUDE protein, C-terminal conserved region HALZ PF02183.18 CEH17631.1 - 0.028 14.6 0.7 0.18 12.1 0.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 CEH17631.1 - 0.17 12.0 35.4 0.34 11.0 5.3 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Sec8_exocyst PF04048.14 CEH17631.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.2 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain TMV_coat PF00721.21 CEH17631.1 - 0.79 9.5 4.6 2.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Virus coat protein (TMV like) IFP_35_N PF07334.13 CEH17631.1 - 0.88 9.7 3.0 1.2 9.2 0.1 2.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Occludin_ELL PF07303.13 CEH17631.1 - 1.2 9.9 20.5 0.57 10.9 1.1 3.4 2 1 2 4 4 4 0 Occludin homology domain SOGA PF11365.8 CEH17631.1 - 1.3 10.1 20.6 1.2 10.3 2.5 3.7 2 1 1 3 3 3 0 Protein SOGA PRKG1_interact PF15898.5 CEH17631.1 - 1.8 9.5 31.3 0.21 12.5 12.7 3.5 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain SLATT_5 PF18160.1 CEH17631.1 - 2.2 7.6 7.6 3.7 6.8 7.6 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 SlyX PF04102.12 CEH17631.1 - 2.5 8.8 19.2 5.1 7.8 1.2 4.6 3 1 1 4 4 4 0 SlyX DUF4665 PF15679.5 CEH17631.1 - 4.7 7.9 9.2 0.43 11.2 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) Prefoldin PF02996.17 CEH17631.1 - 5 7.1 21.2 1.1 9.1 0.6 4.5 4 1 1 5 5 5 0 Prefoldin subunit DUF3450 PF11932.8 CEH17631.1 - 6.3 6.0 24.6 5.1 6.3 11.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) gpD PF02925.16 CEH17632.1 - 0.019 14.9 0.4 0.037 14.0 0.4 1.5 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D Saf_2TM PF18303.1 CEH17632.1 - 1.9 8.1 5.2 0.29 10.7 1.1 1.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain NUDIX PF00293.28 CEH17633.1 - 3.6e-15 56.2 0.2 1.3e-14 54.4 0.2 1.8 1 1 0 1 1 1 1 NUDIX domain Septin PF00735.18 CEH17634.1 - 2.5e-110 368.2 0.4 3.2e-110 367.9 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CEH17634.1 - 6.9e-10 39.0 0.0 1.5e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEH17634.1 - 3.4e-06 27.1 0.1 3.5e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 CEH17634.1 - 6.9e-06 25.5 0.4 1.4e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 CEH17634.1 - 9.6e-06 25.7 0.1 0.082 13.0 0.1 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 CEH17634.1 - 1.8e-05 24.4 0.4 0.0015 18.1 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 CEH17634.1 - 0.00018 20.9 0.1 0.00034 20.0 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 CEH17634.1 - 0.00079 19.7 0.2 0.0043 17.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEH17634.1 - 0.00093 19.6 0.0 0.0023 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 CEH17634.1 - 0.0038 17.7 0.3 0.012 16.1 0.0 1.9 2 1 0 2 2 2 1 ABC transporter IIGP PF05049.13 CEH17634.1 - 0.0051 15.9 0.1 0.013 14.5 0.1 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 CEH17634.1 - 0.0093 15.5 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 CEH17634.1 - 0.012 15.8 1.0 0.21 11.7 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain T2SSE PF00437.20 CEH17634.1 - 0.017 14.2 0.1 0.044 12.8 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 CEH17634.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 CEH17634.1 - 0.025 13.8 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Gtr1_RagA PF04670.12 CEH17634.1 - 0.028 13.8 0.1 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 CEH17634.1 - 0.045 12.9 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 CEH17634.1 - 0.053 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CEH17634.1 - 0.3 11.1 3.3 1.1 9.3 0.1 2.9 3 1 0 3 3 3 0 AAA domain Ribosomal_L7Ae PF01248.26 CEH17635.1 - 1.6e-22 79.0 0.2 3e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CEH17635.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 DUF4050 PF13259.6 CEH17635.1 - 0.65 10.3 2.4 0.94 9.8 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) RR_TM4-6 PF06459.12 CEH17635.1 - 2.1 8.1 6.3 3.2 7.5 6.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 baeRF_family10 PF18854.1 CEH17637.1 - 0.012 15.8 1.1 0.049 13.9 1.1 2.0 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 G_glu_transpept PF01019.21 CEH17638.1 - 4.7e-152 507.4 0.1 5.4e-152 507.2 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase COX16 PF14138.6 CEH17639.1 - 1.2e-24 86.6 0.5 1.9e-24 86.0 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 Evr1_Alr PF04777.13 CEH17639.1 - 3.3e-24 85.3 0.1 7.8e-24 84.0 0.1 1.7 1 0 0 1 1 1 1 Erv1 / Alr family DUF3606 PF12244.8 CEH17639.1 - 4.9 7.2 7.3 37 4.4 0.6 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3606) dCMP_cyt_deam_1 PF00383.23 CEH17640.1 - 1.3e-12 47.4 0.1 2.1e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CEH17640.1 - 7.3e-11 42.4 4.7 1.5e-09 38.2 1.6 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region UPF0016 PF01169.19 CEH17641.1 - 4.7e-51 171.0 27.7 1.5e-22 79.7 9.0 3.2 3 0 0 3 3 3 3 Uncharacterized protein family UPF0016 TauE PF01925.19 CEH17641.1 - 0.077 12.6 18.1 0.33 10.6 4.0 2.8 2 1 1 3 3 3 0 Sulfite exporter TauE/SafE DUF4131 PF13567.6 CEH17641.1 - 4 7.1 9.0 3.9 7.1 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) NUDIX PF00293.28 CEH17642.1 - 1.9e-08 34.4 0.0 3.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CBM_11 PF03425.13 CEH17643.1 - 0.14 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) LCAT PF02450.15 CEH17644.1 - 3.1e-88 296.6 0.0 9.9e-88 294.9 0.0 1.7 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CEH17644.1 - 0.0074 16.9 0.6 0.019 15.6 0.1 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family DELLA PF12041.8 CEH17644.1 - 0.04 13.8 0.1 0.36 10.7 0.0 2.5 3 0 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal Lipase_3 PF01764.25 CEH17644.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Spc7 PF08317.11 CEH17645.1 - 0.78 8.6 5.6 1.4 7.8 5.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein GCP_C_terminal PF04130.13 CEH17646.1 - 6.8e-16 58.6 0.1 1.3e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CEH17646.1 - 6.3e-09 35.9 0.0 1.9e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Prefoldin_2 PF01920.20 CEH17647.1 - 3.7e-17 62.2 6.0 4.3e-17 62.0 5.2 1.5 1 1 0 1 1 1 1 Prefoldin subunit DUF641 PF04859.12 CEH17647.1 - 0.00029 21.2 5.3 0.038 14.3 0.3 2.2 2 0 0 2 2 2 2 Plant protein of unknown function (DUF641) Syntaxin-6_N PF09177.11 CEH17647.1 - 0.0025 18.3 2.4 1 9.9 0.1 2.3 2 0 0 2 2 2 2 Syntaxin 6, N-terminal FliD_C PF07195.12 CEH17647.1 - 0.0075 15.7 3.8 0.59 9.5 1.0 2.0 2 0 0 2 2 2 2 Flagellar hook-associated protein 2 C-terminus Spc24 PF08286.11 CEH17647.1 - 0.012 15.8 7.2 0.14 12.4 0.6 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HIP1_clath_bdg PF16515.5 CEH17647.1 - 0.015 15.9 10.1 0.44 11.2 5.0 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2046 PF09755.9 CEH17647.1 - 0.034 13.4 5.6 0.043 13.0 1.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) APG6_N PF17675.1 CEH17647.1 - 0.035 14.6 13.4 0.13 12.8 4.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region APC_basic PF05956.11 CEH17647.1 - 0.07 12.6 1.9 0.082 12.4 1.9 1.0 1 0 0 1 1 1 0 APC basic domain CENP-F_leu_zip PF10473.9 CEH17647.1 - 0.097 12.7 9.0 0.9 9.6 1.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 CEH17647.1 - 0.14 12.6 8.7 0.51 10.8 8.8 1.7 1 1 0 1 1 1 0 Fez1 Rx_N PF18052.1 CEH17647.1 - 0.17 12.2 5.0 1.8 8.9 0.5 2.2 2 0 0 2 2 2 0 Rx N-terminal domain Spc29 PF17082.5 CEH17647.1 - 0.2 11.5 2.4 0.22 11.3 1.6 1.5 1 1 0 1 1 1 0 Spindle Pole Component 29 ERM PF00769.19 CEH17647.1 - 0.2 11.4 13.0 0.48 10.2 12.7 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Prefoldin PF02996.17 CEH17647.1 - 0.28 11.1 6.7 5.2 7.0 0.5 2.6 2 1 1 3 3 3 0 Prefoldin subunit Cluap1 PF10234.9 CEH17647.1 - 0.42 10.0 10.8 2.8 7.3 10.8 1.9 1 1 0 1 1 1 0 Clusterin-associated protein-1 OmpH PF03938.14 CEH17647.1 - 0.6 10.5 15.0 0.13 12.6 5.8 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.9 CEH17647.1 - 0.68 10.7 3.0 2.5 8.8 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 CEH17647.1 - 0.69 9.1 6.3 0.4 9.9 1.8 1.9 1 1 1 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 CEH17647.1 - 0.71 9.2 8.9 2.3 7.5 8.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 CEH17647.1 - 0.74 7.7 3.3 0.79 7.6 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 CEH17647.1 - 1 8.2 11.6 1.3 7.9 2.8 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 CEH17647.1 - 1.1 9.3 11.0 0.84 9.7 1.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding YkyA PF10368.9 CEH17647.1 - 1.3 8.6 10.9 0.25 11.0 1.9 2.1 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Fib_alpha PF08702.10 CEH17647.1 - 1.5 9.0 5.2 11 6.2 0.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.6 CEH17647.1 - 2.1 8.4 16.4 2.3 8.2 3.6 2.2 2 0 0 2 2 2 0 FlxA-like protein TMF_DNA_bd PF12329.8 CEH17647.1 - 2.6 8.1 12.6 2.9 8.0 1.2 2.5 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 CEH17647.1 - 3.5 8.1 6.6 0.75 10.2 0.7 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 CEH17647.1 - 4.2 7.2 9.4 4.2 7.2 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 CEH17647.1 - 4.4 6.5 13.3 0.31 10.3 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 CEH17647.1 - 6.6 6.8 12.5 2.3 8.3 3.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 CEH17647.1 - 6.8 7.4 7.6 3.1 8.5 2.5 2.0 1 1 1 2 2 2 0 Initiation control protein YabA MAM33 PF02330.16 CEH17648.1 - 6.3e-43 147.2 0.2 6.8e-43 147.1 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Peptidase_S9_N PF02897.15 CEH17650.1 - 6.1e-79 265.7 0.0 8.8e-79 265.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CEH17650.1 - 7.9e-48 162.7 0.1 1.4e-47 161.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CEH17650.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_47 PF01532.20 CEH17651.1 - 1e-122 410.3 0.0 1.2e-122 410.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_65m PF03632.15 CEH17652.1 - 7.2e-44 150.2 1.9 4.6e-34 117.9 0.4 3.2 1 1 2 3 3 3 3 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 CEH17652.1 - 1.6e-05 24.7 0.0 4.5e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.25 CEH17652.1 - 0.00019 21.6 0.7 0.0064 16.6 0.7 2.9 1 1 0 1 1 1 1 F5/8 type C domain DNAPolymera_Pol PF11590.8 CEH17652.1 - 0.067 13.1 0.8 9.5 6.2 0.0 2.9 3 0 0 3 3 3 0 DNA polymerase catalytic subunit Pol CobD_Cbib PF03186.13 CEH17654.1 - 0.027 13.7 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 CobD/Cbib protein Orthopox_F6 PF06601.12 CEH17654.1 - 0.084 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Orthopoxvirus F6 protein DUF2934 PF11154.8 CEH17654.1 - 5.7 6.7 8.2 0.13 12.0 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) DUF4331 PF14224.6 CEH17655.1 - 0.18 11.0 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4331) HSP70 PF00012.20 CEH17656.1 - 0.00036 18.9 1.6 0.00053 18.3 0.1 2.0 2 1 1 3 3 3 1 Hsp70 protein Mer2 PF09074.10 CEH17657.1 - 0.032 14.1 0.5 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Mer2 LMBR1 PF04791.16 CEH17657.1 - 0.5 9.2 3.0 6.8 5.5 0.8 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF3450 PF11932.8 CEH17659.1 - 0.0043 16.4 0.6 0.0043 16.4 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 CEH17659.1 - 0.0048 17.0 1.9 2.4 8.2 0.1 2.5 2 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Herpes_ICP4_N PF03584.15 CEH17659.1 - 0.0072 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Herpesvirus ICP4-like protein N-terminal region TBCC_N PF16752.5 CEH17659.1 - 0.016 15.6 8.4 0.13 12.7 0.4 2.9 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain RHD3 PF05879.12 CEH17659.1 - 0.047 11.9 2.3 0.073 11.2 2.3 1.3 1 1 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Beta_protein PF14350.6 CEH17659.1 - 0.05 13.0 0.6 0.093 12.1 0.6 1.5 1 0 0 1 1 1 0 Beta protein CC2-LZ PF16516.5 CEH17659.1 - 0.07 13.5 0.2 0.07 13.5 0.2 2.3 3 1 0 3 3 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator LMBR1 PF04791.16 CEH17659.1 - 0.076 11.9 2.5 0.1 11.5 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein APG17 PF04108.12 CEH17659.1 - 0.12 11.5 8.3 0.18 10.9 0.3 2.5 3 0 0 3 3 3 0 Autophagy protein Apg17 PIN_8 PF18476.1 CEH17659.1 - 0.18 11.6 7.0 0.28 11.0 1.6 2.1 1 1 1 2 2 2 0 PIN like domain DUF641 PF04859.12 CEH17659.1 - 0.22 11.9 3.3 0.56 10.6 0.4 2.5 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) NPV_P10 PF05531.12 CEH17659.1 - 0.3 11.6 2.2 1.5 9.3 0.3 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Mt_ATP-synt_D PF05873.12 CEH17659.1 - 0.32 10.8 2.4 0.39 10.5 0.3 2.1 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Exonuc_VII_L PF02601.15 CEH17659.1 - 0.5 9.9 10.4 0.92 9.0 1.3 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 CEH17659.1 - 0.5 10.5 5.8 0.68 10.1 0.9 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 CEH17659.1 - 0.54 10.5 9.9 0.3 11.3 2.2 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 CEH17659.1 - 0.63 10.1 6.3 0.31 11.1 2.0 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF4407 PF14362.6 CEH17659.1 - 0.71 9.2 3.6 0.91 8.8 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HD_4 PF13328.6 CEH17659.1 - 0.96 9.2 5.2 1.1 8.9 0.0 2.8 3 1 0 3 3 3 0 HD domain LTXXQ PF07813.12 CEH17659.1 - 1.1 10.0 6.2 0.14 12.9 0.9 2.2 3 0 0 3 3 2 0 LTXXQ motif family protein TMPIT PF07851.13 CEH17659.1 - 1.1 8.4 4.1 0.67 9.2 0.4 2.1 2 0 0 2 2 2 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 CEH17659.1 - 2.3 8.3 10.5 0.21 11.7 1.2 3.1 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 CEH17659.1 - 3.2 7.9 10.2 1.2 9.3 3.9 2.5 2 1 0 2 2 2 0 Tropomyosin like TACC_C PF05010.14 CEH17659.1 - 3.6 7.3 9.7 14 5.4 2.5 3.0 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PRELI PF04707.14 CEH17660.1 - 4.4e-16 59.1 0.0 5.5e-07 29.5 0.0 3.1 3 0 0 3 3 3 3 PRELI-like family DUF1651 PF07864.11 CEH17660.1 - 0.082 13.3 0.0 0.61 10.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1651) MaoC_dehydratas PF01575.19 CEH17661.1 - 0.00024 20.6 0.1 0.00045 19.8 0.1 1.4 1 0 0 1 1 1 1 MaoC like domain p450 PF00067.22 CEH17662.1 - 8.1e-51 173.2 0.0 9.9e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DASH_Duo1 PF08651.10 CEH17662.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 CorA PF01544.18 CEH17664.1 - 3.6e-45 154.5 0.5 4.9e-45 154.1 0.5 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 CEH17664.1 - 0.076 13.1 0.6 0.16 12.0 0.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_cc PF11790.8 CEH17665.1 - 1.1e-51 175.7 0.9 1.5e-51 175.3 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.13 CEH17665.1 - 0.012 14.6 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Glyco_hydro_59 PF02057.15 CEH17665.1 - 0.047 12.9 0.3 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 CMD PF02627.20 CEH17666.1 - 1.1e-19 70.2 0.2 1.7e-19 69.6 0.2 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Cerato-platanin PF07249.12 CEH17671.1 - 0.016 15.3 3.3 0.03 14.5 0.4 2.7 2 1 1 3 3 3 0 Cerato-platanin DPBB_1 PF03330.18 CEH17671.1 - 0.045 14.0 0.2 0.045 14.0 0.2 2.4 3 1 0 3 3 3 0 Lytic transglycolase Apt1 PF10351.9 CEH17671.1 - 0.07 12.0 3.8 0.082 11.8 3.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SWI-SNF_Ssr4 PF08549.10 CEH17671.1 - 0.28 9.8 3.7 0.31 9.6 3.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Macoilin PF09726.9 CEH17671.1 - 7.3 5.0 6.8 8.7 4.8 6.8 1.1 1 0 0 1 1 1 0 Macoilin family ADH_zinc_N_2 PF13602.6 CEH17673.1 - 2.5e-13 51.2 0.4 1e-12 49.2 0.4 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CEH17673.1 - 0.008 16.2 0.1 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Rhomboid PF01694.22 CEH17674.1 - 2.3e-29 102.4 9.2 4.9e-29 101.3 9.2 1.6 1 0 0 1 1 1 1 Rhomboid family DUF4448 PF14610.6 CEH17676.1 - 0.019 14.8 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Methyltransf_28 PF02636.17 CEH17677.1 - 1.3e-31 110.2 0.0 2e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 CEH17677.1 - 0.00014 21.1 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 CEH17677.1 - 0.0012 19.5 0.1 0.0088 16.8 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain PRMT5 PF05185.16 CEH17677.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.6 CEH17677.1 - 0.036 14.8 0.0 6.4 7.6 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain BAT PF15915.5 CEH17678.1 - 0.00054 19.9 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 GAF and HTH_10 associated domain RRM_1 PF00076.22 CEH17678.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.6 CEH17678.1 - 0.43 10.5 6.9 1.2 9.1 6.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEH17678.1 - 0.85 9.6 14.8 1.7 8.6 14.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DDE_Tnp_4 PF13359.6 CEH17679.1 - 1.5e-20 73.4 0.1 4.2e-20 72.0 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CEH17679.1 - 1.5e-07 31.3 0.1 1.2e-06 28.3 0.1 2.5 1 1 0 1 1 1 1 Transposase DDE domain Fip1 PF05182.13 CEH17679.1 - 0.028 13.9 0.1 0.068 12.7 0.1 1.6 1 0 0 1 1 1 0 Fip1 motif DUF4818 PF16089.5 CEH17679.1 - 0.17 12.4 0.4 0.47 10.9 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4818) DUF3452 PF11934.8 CEH17679.1 - 0.24 11.0 1.1 1.2 8.7 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) MADF_DNA_bdg PF10545.9 CEH17680.1 - 0.068 13.5 1.5 0.59 10.5 0.4 2.6 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FANCD2OS PF15124.6 CEH17681.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.0 1 0 0 1 1 1 0 FANCD2 opposite strand protein HSP70 PF00012.20 CEH17682.1 - 3.3e-192 639.9 12.3 1.4e-129 433.0 1.8 3.1 2 1 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 CEH17682.1 - 1.8e-10 40.2 0.2 0.00021 20.2 0.2 2.2 1 1 1 2 2 2 2 MreB/Mbl protein Abhydrolase_6 PF12697.7 CEH17682.1 - 0.0067 17.0 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family FGGY_C PF02782.16 CEH17682.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Abhydrolase_1 PF00561.20 CEH17682.1 - 0.024 14.3 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DDR PF08841.10 CEH17682.1 - 0.024 13.6 0.8 0.11 11.5 0.3 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CEH17682.1 - 0.086 12.1 0.9 0.18 11.1 0.9 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase PGAP1 PF07819.13 CEH17682.1 - 0.16 11.6 0.0 0.54 9.9 0.0 1.8 1 0 0 1 1 1 0 PGAP1-like protein PIN_8 PF18476.1 CEH17682.1 - 6.3 6.6 5.5 18 5.1 0.1 2.2 2 0 0 2 2 2 0 PIN like domain Bacillus_HBL PF05791.11 CEH17683.1 - 0.065 13.0 0.1 0.078 12.8 0.1 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) zf-C2H2 PF00096.26 CEH17684.1 - 2.8e-18 65.3 29.6 2.4e-05 24.5 1.9 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEH17684.1 - 3.3e-18 65.2 20.6 7.5e-06 26.1 0.2 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEH17684.1 - 5.9e-08 32.9 27.2 0.012 16.3 1.6 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEH17684.1 - 0.04 14.2 6.1 0.67 10.3 0.2 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CEH17684.1 - 0.06 14.0 9.3 0.85 10.3 0.1 4.0 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-TRAF PF02176.18 CEH17684.1 - 1.5 9.6 11.7 0.7 10.6 0.3 3.2 2 1 1 3 3 3 0 TRAF-type zinc finger BSP_II PF05432.11 CEH17684.1 - 2.6 7.7 14.0 5.8 6.5 14.0 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) zf-met PF12874.7 CEH17684.1 - 3.7 8.1 10.0 7.9 7.0 0.5 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type PTCB-BRCT PF12738.7 CEH17685.1 - 1.2e-12 47.6 0.0 1.2e-05 25.2 0.0 3.9 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 CEH17685.1 - 8.8e-09 35.6 0.0 0.00018 21.8 0.0 4.0 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CEH17685.1 - 2.9e-05 24.4 0.0 0.0039 17.6 0.0 3.1 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CEH17685.1 - 0.0033 17.7 0.3 0.089 13.1 0.0 3.2 4 0 0 4 4 4 1 DNA ligase 3 BRCT domain HSF_DNA-bind PF00447.17 CEH17686.1 - 9.7e-32 109.5 2.1 1.3e-31 109.1 0.7 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 CEH17686.1 - 1.4e-25 89.6 1.2 5.6e-25 87.7 0.2 2.2 2 0 0 2 2 2 1 Response regulator receiver domain GOLGA2L5 PF15070.6 CEH17686.1 - 0.029 13.1 6.6 0.044 12.4 6.6 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 MobL PF18555.1 CEH17686.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 MobL relaxases AATF-Che1 PF13339.6 CEH17686.1 - 0.56 10.9 2.2 1.5 9.5 2.2 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor PI3_PI4_kinase PF00454.27 CEH17687.1 - 2.4e-54 184.8 0.0 3.7e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 CEH17687.1 - 1.6e-18 67.2 0.0 9.2e-18 64.8 0.0 2.4 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 CEH17687.1 - 5.4e-09 35.7 0.5 1.8e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 FATC domain DUF5400 PF17379.2 CEH17687.1 - 0.066 13.7 0.5 13 6.3 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5400) HEAT PF02985.22 CEH17687.1 - 0.18 12.1 2.9 4.1 7.9 0.1 4.4 3 0 0 3 3 3 0 HEAT repeat FHA PF00498.26 CEH17688.1 - 8.3e-06 26.1 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Gti1_Pac2 PF09729.9 CEH17690.1 - 5e-60 202.7 0.1 2e-59 200.7 0.0 2.0 2 1 0 2 2 2 1 Gti1/Pac2 family Peptidase_S8 PF00082.22 CEH17691.1 - 1.9e-29 102.9 10.0 3.2e-29 102.1 10.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CEH17691.1 - 4.2e-13 49.8 0.2 7.5e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ribosomal_L14e PF01929.17 CEH17692.1 - 1.1e-30 105.9 1.3 1.5e-30 105.5 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CEH17692.1 - 4.7e-07 29.6 0.3 7.7e-07 28.9 0.3 1.4 1 0 0 1 1 1 1 KOW motif DUF1269 PF06897.12 CEH17692.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Rib_5-P_isom_A PF06026.14 CEH17693.1 - 1.4e-59 200.6 0.0 1.7e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) XPG_I_2 PF12813.7 CEH17694.1 - 0.00036 20.1 0.1 0.00081 18.9 0.1 1.6 1 0 0 1 1 1 1 XPG domain containing DUF3146 PF11344.8 CEH17694.1 - 0.0056 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3146) HSP70 PF00012.20 CEH17696.1 - 3.5e-259 861.1 14.7 3.9e-259 860.9 14.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEH17696.1 - 2.2e-12 46.5 5.8 2e-10 40.0 2.8 2.6 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CEH17696.1 - 0.0007 20.0 9.3 0.099 13.1 0.1 4.1 3 1 0 3 3 3 2 Cell division protein FtsA DUF1798 PF08807.10 CEH17696.1 - 0.028 14.5 1.1 0.069 13.3 1.1 1.6 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Ploopntkinase3 PF18751.1 CEH17696.1 - 0.19 11.7 1.9 3.4 7.5 0.0 2.7 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 FUSC PF04632.12 CEH17696.1 - 1.1 7.7 4.2 1.7 7.0 4.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.22 CEH17696.1 - 2.5 8.4 10.1 7.5 6.8 10.1 1.9 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Raco_middle PF17651.1 CEH17696.1 - 8.9 6.0 7.7 18 5.0 0.0 3.8 4 1 1 5 5 5 0 RACo middle region His_Phos_1 PF00300.22 CEH17698.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Methyltransf_11 PF08241.12 CEH17699.1 - 1.9e-09 38.0 0.0 4.7e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH17699.1 - 2.9e-09 37.5 0.0 2e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH17699.1 - 8.9e-07 28.8 0.0 3.1e-06 27.1 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH17699.1 - 0.00021 21.9 0.0 0.00087 20.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH17699.1 - 0.005 16.7 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEH17699.1 - 0.027 13.9 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DnaB_bind PF10410.9 CEH17699.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase RDM PF11002.8 CEH17699.1 - 0.18 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 RFPL defining motif (RDM) TPR_2 PF07719.17 CEH17700.1 - 2e-10 40.0 2.5 0.00014 21.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEH17700.1 - 1.8e-08 33.8 1.6 0.00073 19.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEH17700.1 - 3.7e-06 26.7 0.1 0.015 15.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEH17700.1 - 5.5e-06 26.9 7.7 0.015 16.0 5.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEH17700.1 - 1.8e-05 24.3 0.9 0.11 12.2 0.1 3.2 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 CEH17700.1 - 0.00026 21.6 6.7 0.014 16.1 0.4 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEH17700.1 - 0.0011 19.5 1.5 0.057 13.9 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 CEH17700.1 - 0.0029 17.7 1.0 0.071 13.2 1.0 2.1 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 CEH17700.1 - 0.008 16.5 2.8 1.2 9.4 0.4 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 CEH17700.1 - 0.023 15.1 2.5 0.12 12.8 2.5 2.0 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 CEH17700.1 - 0.055 13.6 1.3 0.098 12.8 0.4 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEH17700.1 - 0.084 12.9 0.5 4 7.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEH17700.1 - 0.18 12.5 2.5 52 4.8 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEH17700.1 - 0.26 11.2 2.5 23 5.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 CEH17700.1 - 0.35 11.6 3.0 6.9 7.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Inositol_P PF00459.25 CEH17701.1 - 2.5e-50 171.5 0.0 1.2e-49 169.3 0.0 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family PX PF00787.24 CEH17702.1 - 5.2e-17 61.8 0.0 1.3e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 PX domain Zn_clus PF00172.18 CEH17703.1 - 1.3e-08 34.8 8.0 2.4e-08 34.0 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 CEH17703.1 - 0.34 11.4 4.4 3.2 8.3 0.6 2.4 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family BAR PF03114.18 CEH17704.1 - 7e-42 143.7 3.8 1e-41 143.2 3.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CEH17704.1 - 6.2e-15 54.5 0.0 1.2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEH17704.1 - 3.6e-13 49.2 0.2 5.6e-13 48.5 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEH17704.1 - 1.7e-09 37.2 0.1 2.8e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain FAM92 PF06730.11 CEH17704.1 - 0.0049 16.3 1.9 0.0075 15.7 1.2 1.6 1 1 1 2 2 2 1 FAM92 protein CALCOCO1 PF07888.11 CEH17707.1 - 1.7e-05 23.9 41.3 1.7e-05 23.9 41.3 8.6 3 2 5 8 8 8 2 Calcium binding and coiled-coil domain (CALCOCO1) like MscS_porin PF12795.7 CEH17707.1 - 0.0039 16.8 23.2 0.0039 16.8 23.2 12.3 4 3 4 10 10 10 3 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 CEH17707.1 - 0.0046 17.0 18.2 0.0046 17.0 18.2 17.5 7 4 10 19 19 19 3 TPR/MLP1/MLP2-like protein DUF244 PF03112.14 CEH17707.1 - 0.069 13.0 0.8 0.71 9.7 0.1 2.9 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF HTH_34 PF13601.6 CEH17707.1 - 0.069 13.3 0.9 4.8 7.4 0.0 3.7 3 0 0 3 3 3 0 Winged helix DNA-binding domain NMD3 PF04981.13 CEH17708.1 - 6.4e-82 274.7 1.8 1e-81 274.0 1.8 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 CEH17708.1 - 0.036 14.1 3.9 1.3 9.1 3.9 2.6 1 1 0 1 1 1 0 Double zinc ribbon SUIM_assoc PF16619.5 CEH17708.1 - 0.041 13.9 0.2 40 4.4 0.0 3.9 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Plus-3 PF03126.18 CEH17709.1 - 2.2e-11 44.3 0.2 1e-08 35.6 0.2 2.6 1 1 0 1 1 1 1 Plus-3 domain PRIMA1 PF16101.5 CEH17709.1 - 0.072 13.1 1.6 0.14 12.2 1.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SAM_2 PF07647.17 CEH17710.1 - 9.5e-10 38.5 0.0 1.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEH17710.1 - 3.6e-06 27.3 0.0 7.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 CEH17710.1 - 0.028 14.5 0.2 0.07 13.2 0.2 1.6 1 0 0 1 1 1 0 IGR protein motif SAM_3 PF18016.1 CEH17710.1 - 0.038 13.8 0.2 1 9.2 0.0 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 CEH17710.1 - 0.09 13.0 0.2 0.22 11.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Gtr1_RagA PF04670.12 CEH17712.1 - 2.8e-30 105.4 0.0 2.1e-10 40.3 0.0 3.1 3 0 0 3 3 3 3 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEH17712.1 - 0.00015 21.8 0.0 0.00032 20.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CEH17712.1 - 0.00029 21.3 0.0 0.00058 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Arf PF00025.21 CEH17712.1 - 0.013 15.0 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_14 PF13173.6 CEH17712.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CEH17712.1 - 0.099 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ApeC PF16977.5 CEH17713.1 - 0.0071 16.3 0.1 0.01 15.8 0.1 1.2 1 0 0 1 1 1 1 C-terminal domain of apextrin Sec63 PF02889.16 CEH17714.1 - 4.7e-22 78.4 0.0 2.4e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CEH17714.1 - 1.1e-15 57.8 0.3 3.8e-09 36.5 0.0 3.1 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH17714.1 - 1e-09 38.7 0.0 9.2e-09 35.6 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH17714.1 - 2.7e-07 30.8 0.0 5.2e-05 23.3 0.0 2.5 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CEH17714.1 - 0.003 17.3 0.3 0.0098 15.6 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CEH17714.1 - 0.0049 17.2 0.7 0.022 15.1 0.1 2.4 3 1 0 3 3 3 1 AAA domain MarR PF01047.22 CEH17714.1 - 0.0057 16.5 0.0 0.02 14.8 0.0 2.0 1 0 0 1 1 1 1 MarR family NTPase_1 PF03266.15 CEH17714.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 CEH17714.1 - 0.066 13.5 0.3 20 5.5 0.0 2.8 1 1 1 2 2 2 0 AAA domain UvrD-helicase PF00580.21 CEH17714.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 CEH17714.1 - 0.17 11.3 0.0 0.43 10.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region adh_short PF00106.25 CEH17715.1 - 1.3e-37 129.2 0.0 1.6e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH17715.1 - 4.5e-19 69.0 0.0 5.9e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH17715.1 - 1.8e-10 41.0 0.0 2.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEH17715.1 - 4.8e-06 26.2 0.0 7.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 CEH17715.1 - 4.1e-05 24.1 0.0 9.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 CEH17715.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CEH17715.1 - 0.0024 17.9 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 CEH17715.1 - 0.0044 16.2 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF4142 PF13628.6 CEH17715.1 - 0.014 15.6 0.1 0.027 14.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) NAD_binding_10 PF13460.6 CEH17715.1 - 0.023 14.6 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 CEH17715.1 - 0.028 14.3 0.1 0.054 13.4 0.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 CEH17715.1 - 0.033 13.7 0.1 0.046 13.3 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family DUF692 PF05114.13 CEH17715.1 - 0.035 13.3 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF692) GDP_Man_Dehyd PF16363.5 CEH17715.1 - 0.039 13.3 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 CEH17715.1 - 0.045 14.0 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Mastoparan_2 PF08251.11 CEH17715.1 - 3.5 8.1 4.4 0.69 10.3 0.4 2.0 2 0 0 2 2 1 0 Mastoparan peptide DNA_ligase_A_C PF04679.15 CEH17716.1 - 1.2e-08 35.4 0.0 0.0019 18.8 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase C terminal region Acetyltransf_10 PF13673.7 CEH17717.1 - 9.6e-10 38.5 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEH17717.1 - 4.8e-09 36.5 0.0 6.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEH17717.1 - 2.5e-07 30.9 0.0 3.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CEH17717.1 - 0.00048 20.0 0.0 0.0021 18.0 0.0 1.8 1 1 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 CEH17717.1 - 0.00066 19.8 0.0 0.00081 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TauD PF02668.16 CEH17718.1 - 2e-24 86.8 2.3 4.1e-23 82.5 2.3 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA PF00004.29 CEH17719.1 - 0.0014 19.1 0.0 0.0035 17.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEH17719.1 - 0.0063 16.9 3.7 0.0099 16.3 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 CEH17719.1 - 0.033 14.1 0.0 0.076 12.9 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 CEH17719.1 - 0.035 14.4 0.1 0.13 12.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.13 CEH17720.1 - 3.2e-26 92.5 0.0 5.3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEH17720.1 - 0.037 13.5 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CEH17720.1 - 0.11 12.1 0.2 0.2 11.3 0.2 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 CEH17720.1 - 0.22 10.3 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Say1_Mug180 PF10340.9 CEH17720.1 - 0.29 10.0 0.0 0.44 9.4 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase F-box-like PF12937.7 CEH17721.1 - 4.4e-05 23.3 0.0 0.00022 21.1 0.0 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 CEH17721.1 - 0.032 14.1 2.4 1.8 8.5 2.4 2.9 1 1 0 1 1 1 0 F-box domain HORMA PF02301.18 CEH17723.1 - 1.1e-59 201.6 0.0 2.4e-59 200.5 0.0 1.6 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 CEH17723.1 - 8.1e-08 32.0 7.4 1.5e-07 31.2 7.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CEH17723.1 - 0.0016 18.0 2.8 0.0027 17.2 2.8 1.4 1 0 0 1 1 1 1 PHD-finger ARF7EP_C PF14949.6 CEH17723.1 - 1.3 9.7 7.0 15 6.3 2.6 3.0 2 0 0 2 2 2 0 ARF7 effector protein C-terminus Profilin PF00235.19 CEH17725.1 - 3.8e-47 159.7 0.0 4.2e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Profilin Sec10 PF07393.11 CEH17726.1 - 9.9e-97 325.1 0.0 5e-96 322.7 0.0 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 CEH17726.1 - 2.6e-05 24.0 0.0 5.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEH17726.1 - 0.00093 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain ADK PF00406.22 CEH17727.1 - 5.6e-38 130.4 0.0 6.6e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEH17727.1 - 3.2e-18 66.5 0.0 4.6e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CEH17727.1 - 1.6e-14 53.6 0.0 2.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CEH17727.1 - 3e-06 27.8 0.0 5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CEH17727.1 - 0.024 14.9 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEH17727.1 - 0.04 14.1 0.1 0.06 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CEH17727.1 - 0.17 11.6 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Mito_carr PF00153.27 CEH17728.1 - 1.2e-27 95.6 3.9 1.3e-14 53.9 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Zip PF02535.22 CEH17729.1 - 0.019 14.2 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Ctr PF04145.15 CEH17731.1 - 8.5e-34 117.3 0.0 1.5e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 Ctr copper transporter family DUF1150 PF06620.11 CEH17731.1 - 0.025 14.7 0.1 0.044 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) DUF1146 PF06612.11 CEH17731.1 - 0.18 11.9 2.1 0.41 10.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) ABC_membrane PF00664.23 CEH17732.1 - 3.9e-77 259.6 22.2 1.4e-42 146.2 9.7 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEH17732.1 - 2.4e-62 209.5 0.0 5.3e-31 108.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEH17732.1 - 3.8e-11 42.8 0.0 0.0044 16.5 0.0 3.6 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEH17732.1 - 2e-10 41.3 0.4 0.00012 22.5 0.2 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CEH17732.1 - 1.3e-08 35.2 0.3 0.016 15.5 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CEH17732.1 - 1.8e-06 27.6 0.2 0.031 14.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CEH17732.1 - 2.8e-06 27.3 0.0 7.5 6.3 0.0 4.2 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 CEH17732.1 - 5.2e-06 26.5 0.0 0.6 10.1 0.0 4.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CEH17732.1 - 5.2e-06 27.0 0.0 0.16 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CEH17732.1 - 1.8e-05 24.7 0.2 0.1 12.5 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase ABC_ATPase PF09818.9 CEH17732.1 - 3.2e-05 22.9 0.0 0.03 13.1 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 CEH17732.1 - 3.6e-05 23.4 0.1 0.76 9.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 CEH17732.1 - 4.1e-05 23.8 0.0 0.054 13.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CEH17732.1 - 9e-05 22.7 0.1 0.21 11.6 0.0 2.8 3 0 0 3 3 2 2 Helicase HerA, central domain SbcCD_C PF13558.6 CEH17732.1 - 9.2e-05 22.6 1.7 0.75 10.1 0.2 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 CEH17732.1 - 0.00042 20.7 0.0 0.85 10.0 0.0 2.5 2 0 0 2 2 2 2 RNA helicase APS_kinase PF01583.20 CEH17732.1 - 0.00045 20.1 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase ATP-synt_ab PF00006.25 CEH17732.1 - 0.00052 19.7 0.0 0.82 9.3 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 CEH17732.1 - 0.00067 19.0 1.4 0.58 9.4 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA PF00004.29 CEH17732.1 - 0.00073 20.0 0.0 11 6.5 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CEH17732.1 - 0.00076 19.3 0.1 1.3 8.7 0.0 3.3 4 0 0 4 4 2 1 AAA domain AAA_7 PF12775.7 CEH17732.1 - 0.00076 19.0 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 CEH17732.1 - 0.0037 17.2 0.0 3.7 7.4 0.0 2.8 2 0 0 2 2 2 1 NACHT domain PRK PF00485.18 CEH17732.1 - 0.0063 16.3 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.26 CEH17732.1 - 0.0072 16.0 0.0 4.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CEH17732.1 - 0.0077 16.0 0.1 10 5.8 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein G-alpha PF00503.20 CEH17732.1 - 0.0099 15.1 0.0 0.9 8.6 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_28 PF13521.6 CEH17732.1 - 0.011 16.0 0.3 9.2 6.5 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 CEH17732.1 - 0.011 15.4 0.1 3.6 7.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain CbiA PF01656.23 CEH17732.1 - 0.012 15.6 0.2 5.5 7.1 0.0 3.0 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TniB PF05621.11 CEH17732.1 - 0.024 14.0 0.0 25 4.2 0.0 3.4 3 0 0 3 3 3 0 Bacterial TniB protein Sigma54_activ_2 PF14532.6 CEH17732.1 - 0.031 14.4 0.0 14 5.8 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_15 PF13175.6 CEH17732.1 - 0.032 13.9 0.0 3.1 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 CEH17732.1 - 0.038 14.4 0.1 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CEH17732.1 - 0.06 13.4 0.0 20 5.3 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 CEH17732.1 - 0.1 12.5 0.0 7.4 6.4 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NB-ARC PF00931.22 CEH17732.1 - 0.12 11.6 0.1 14 4.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Thymidylate_kin PF02223.17 CEH17732.1 - 0.12 12.0 0.0 18 4.9 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase Viral_helicase1 PF01443.18 CEH17732.1 - 0.14 11.9 0.0 24 4.6 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 CEH17732.1 - 0.17 12.4 0.1 14 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain FA_desaturase PF00487.24 CEH17732.1 - 2.1 8.1 3.9 9.4 6.0 3.9 2.1 1 0 0 1 1 1 0 Fatty acid desaturase Cyclin_N PF00134.23 CEH17733.1 - 2e-08 34.1 0.0 3.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CEH17733.1 - 0.00017 22.0 0.2 0.00017 22.0 0.2 2.6 2 1 0 2 2 2 1 Cyclin NolX PF05819.11 CEH17734.1 - 0.088 12.1 0.0 0.088 12.1 0.0 1.0 1 0 0 1 1 1 0 NolX protein CorA PF01544.18 CEH17736.1 - 5.2e-07 29.3 1.3 7.5e-07 28.8 1.3 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein BRI3BP PF14965.6 CEH17736.1 - 0.1 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Negative regulator of p53/TP53 BTB PF00651.31 CEH17737.1 - 2.1e-10 40.8 0.0 1.6e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain CAP_GLY PF01302.25 CEH17737.1 - 1.7e-07 31.2 0.0 7.5e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 CAP-Gly domain zf-Tim10_DDP PF02953.15 CEH17738.1 - 4.2e-09 35.9 1.4 7.8e-09 35.1 1.4 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FAD_binding_4 PF01565.23 CEH17739.1 - 3.2e-27 94.9 1.4 5.4e-27 94.2 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CEH17739.1 - 3.1e-10 40.0 0.0 7.4e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like IF4E PF01652.18 CEH17740.1 - 3.7e-47 160.1 0.0 5.7e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Abhydrolase_3 PF07859.13 CEH17741.1 - 6.4e-36 124.2 0.2 8e-36 123.9 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 CEH17741.1 - 0.00013 21.6 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CEH17741.1 - 0.0054 16.2 0.2 0.069 12.6 0.2 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 CEH17741.1 - 0.0058 15.6 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S15 PF02129.18 CEH17741.1 - 0.041 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 CEH17741.1 - 0.071 12.0 0.1 0.73 8.6 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family Chlorophyllase PF07224.11 CEH17741.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Pro-kuma_activ PF09286.11 CEH17742.1 - 4.2e-33 114.6 0.0 1.2e-32 113.1 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CEH17742.1 - 4.7e-07 29.4 0.2 7.8e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Subtilase family Sugar_tr PF00083.24 CEH17743.1 - 1.6e-123 413.0 25.3 1.8e-123 412.8 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEH17743.1 - 1.1e-16 60.7 35.4 1.1e-16 60.7 35.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 CEH17744.1 - 3.5e-13 49.9 0.9 4.4e-13 49.6 0.9 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH17744.1 - 6.1e-06 27.0 1.9 9.2e-06 26.4 1.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 CEH17744.1 - 0.00014 20.9 0.3 0.003 16.5 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 CEH17744.1 - 0.0011 18.3 0.1 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 CAP_GLY PF01302.25 CEH17744.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.6 2 0 0 2 2 2 0 CAP-Gly domain VirJ PF06057.11 CEH17744.1 - 0.031 14.2 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 CEH17744.1 - 0.05 13.4 0.0 9.9 5.9 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 CEH17744.1 - 0.093 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 CEH17744.1 - 0.093 12.2 0.3 2.5 7.5 0.1 2.7 2 1 0 2 2 2 0 Prolyl oligopeptidase family LIDHydrolase PF10230.9 CEH17744.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase KilA-N PF04383.13 CEH17745.1 - 0.0014 18.5 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 KilA-N domain Ham1p_like PF01725.16 CEH17746.1 - 1.6e-51 174.9 0.0 1.8e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DnaJ_C PF01556.18 CEH17747.1 - 3e-30 105.2 0.0 3.9e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CEH17747.1 - 1.8e-06 28.2 8.6 2.9e-06 27.5 8.6 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-NADH-PPase PF09297.11 CEH17747.1 - 0.92 9.2 4.5 0.5 10.1 0.6 2.5 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Anti-TRAP PF15777.5 CEH17747.1 - 2.2 8.3 6.5 2.8 8.0 4.6 2.2 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-TFIIB PF13453.6 CEH17747.1 - 2.4 7.6 5.1 7.4 6.0 5.1 1.8 1 1 0 1 1 1 0 Transcription factor zinc-finger Pkinase PF00069.25 CEH17749.1 - 8.5e-25 87.6 0.0 9.6e-24 84.2 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17749.1 - 3.3e-10 39.7 0.0 5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH17749.1 - 0.00026 19.9 0.0 0.00049 19.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEH17749.1 - 0.037 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ER_lumen_recept PF00810.18 CEH17750.1 - 2.1e-54 184.3 6.6 3.1e-54 183.8 6.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CEH17750.1 - 0.017 14.9 7.3 4.1 7.3 0.2 4.1 3 1 1 4 4 4 0 PQ loop repeat CMS1 PF14617.6 CEH17751.1 - 5.7e-36 124.1 14.4 2.5e-20 72.9 0.1 2.8 1 1 2 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit tRNA_synt_1c_R2 PF04557.15 CEH17751.1 - 6.6 7.7 9.9 7.8 7.5 2.7 2.5 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 ALO PF04030.14 CEH17752.1 - 7.5e-62 209.5 0.0 2.5e-53 181.5 0.0 2.4 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CEH17752.1 - 3.4e-15 56.0 0.0 8.7e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Gemini_AL1_M PF08283.11 CEH17752.1 - 0.17 12.0 0.0 0.72 10.0 0.0 1.9 2 0 0 2 2 2 0 Geminivirus rep protein central domain DUF4097 PF13349.6 CEH17754.1 - 0.0012 18.3 0.1 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 Putative adhesin Myosin_head PF00063.21 CEH17755.1 - 3.7e-266 884.7 0.0 2.5e-265 882.0 0.0 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CEH17755.1 - 6.3e-13 47.5 121.5 6.3e-13 47.5 121.5 3.1 3 0 0 3 3 3 2 Myosin tail Myosin_N PF02736.19 CEH17755.1 - 2e-06 27.5 0.0 4.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Tropomyosin_1 PF12718.7 CEH17755.1 - 0.0058 16.8 16.7 0.0058 16.8 16.7 9.6 3 2 6 9 9 9 2 Tropomyosin like DUF4600 PF15372.6 CEH17755.1 - 0.0087 16.5 10.1 0.0087 16.5 10.1 9.0 5 2 3 9 9 9 1 Domain of unknown function (DUF4600) AAA_22 PF13401.6 CEH17755.1 - 0.36 11.1 0.0 0.36 11.1 0.0 4.6 4 1 1 5 5 5 0 AAA domain HCNGP PF07818.13 CEH17756.1 - 7.8e-18 64.9 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein Barttin PF15462.6 CEH17756.1 - 3.8 7.2 10.0 0.23 11.2 1.9 2.3 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Sod_Fe_C PF02777.18 CEH17757.1 - 1.9e-37 127.5 0.5 3.8e-37 126.5 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CEH17757.1 - 2.6e-33 114.3 3.5 6e-33 113.2 3.5 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain SMC_Nse1 PF07574.13 CEH17759.1 - 2.5e-29 102.6 0.0 1.6e-28 99.9 0.0 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CEH17759.1 - 1.2e-07 31.9 5.7 4.2e-07 30.2 5.7 1.9 1 1 0 1 1 1 1 RING-like domain NOA36 PF06524.12 CEH17759.1 - 0.016 14.6 5.3 0.024 14.0 5.3 1.3 1 0 0 1 1 1 0 NOA36 protein zf-HC5HC2H PF13771.6 CEH17759.1 - 0.16 12.3 5.1 0.055 13.7 2.2 1.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-ribbon_3 PF13248.6 CEH17759.1 - 0.95 9.0 5.4 3.2 7.3 0.6 3.0 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 CEH17759.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.6 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Zn_Tnp_IS91 PF14319.6 CEH17759.1 - 1.7 8.7 6.1 6.4 6.9 0.5 2.8 3 0 0 3 3 3 0 Transposase zinc-binding domain FYDLN_acid PF09538.10 CEH17759.1 - 2 9.2 12.8 8.6 7.1 12.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) HTH_31 PF13560.6 CEH17760.1 - 0.029 14.7 0.1 0.057 13.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S19 PF00203.21 CEH17762.1 - 1.7e-30 104.7 0.3 2.3e-30 104.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 CEH17762.1 - 0.0098 16.0 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH SKI PF01202.22 CEH17763.1 - 3.9e-24 85.6 0.0 7e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase DHquinase_I PF01487.15 CEH17763.1 - 2.8e-14 53.9 0.0 2.7e-10 40.9 0.0 2.5 1 1 1 2 2 2 2 Type I 3-dehydroquinase AAA PF00004.29 CEH17763.1 - 0.083 13.3 0.1 0.26 11.7 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEH17763.1 - 0.086 13.2 0.4 0.88 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain MbeD_MobD PF04899.12 CEH17764.1 - 0.091 12.9 1.1 0.54 10.4 0.1 2.4 2 0 0 2 2 2 0 MbeD/MobD like G-alpha PF00503.20 CEH17765.1 - 2.4e-95 319.7 0.0 3.4e-95 319.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEH17765.1 - 1.4e-12 47.4 0.1 8.1e-08 31.9 0.0 2.9 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.6 CEH17765.1 - 0.0011 19.2 0.0 0.0031 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEH17765.1 - 0.002 17.9 0.0 0.0042 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEH17765.1 - 0.0076 16.6 0.5 0.022 15.2 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 CEH17765.1 - 0.011 16.0 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CEH17765.1 - 0.017 15.6 0.4 0.1 13.1 0.0 2.2 1 1 1 2 2 2 0 ABC transporter TniB PF05621.11 CEH17765.1 - 0.019 14.4 0.2 0.034 13.5 0.2 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Myosin_head PF00063.21 CEH17765.1 - 0.033 12.4 0.0 0.047 11.9 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Rad17 PF03215.15 CEH17765.1 - 0.042 13.8 0.2 0.097 12.6 0.1 1.6 2 0 0 2 2 1 0 Rad17 P-loop domain NB-ARC PF00931.22 CEH17765.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 CEH17765.1 - 0.06 13.2 0.0 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Mg_chelatase PF01078.21 CEH17765.1 - 0.069 12.5 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CEH17765.1 - 0.082 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEH17765.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 CEH17765.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain UPF0242 PF06785.11 CEH17766.1 - 1 9.4 2.6 12 5.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MARVEL PF01284.23 CEH17766.1 - 7.7 6.5 10.3 0.34 10.9 0.1 2.8 3 1 0 3 3 3 0 Membrane-associating domain Thaumatin PF00314.17 CEH17767.1 - 1.7e-10 40.9 0.9 4.8e-10 39.4 1.0 1.6 1 1 0 1 1 1 1 Thaumatin family Pribosyltran PF00156.27 CEH17768.1 - 1.2e-15 57.4 0.1 1.4e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CEH17768.1 - 0.0025 17.3 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase NMO PF03060.15 CEH17771.1 - 2.1e-48 165.4 0.8 1.2e-46 159.6 0.8 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CEH17771.1 - 7.5e-09 35.0 0.6 0.00092 18.3 0.5 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CEH17771.1 - 0.0016 17.6 0.5 0.0023 17.0 0.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1902 PF08972.11 CEH17771.1 - 0.013 15.4 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) TMP-TENI PF02581.17 CEH17771.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase His_biosynth PF00977.21 CEH17771.1 - 0.096 12.1 0.1 0.21 11.0 0.1 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein CCT_2 PF09425.10 CEH17772.1 - 0.13 12.2 1.5 0.13 12.2 1.5 2.0 2 0 0 2 2 2 0 Divergent CCT motif Acyltransferase PF01553.21 CEH17773.1 - 2.9e-11 43.1 0.0 0.00015 21.3 0.0 2.6 3 0 0 3 3 3 2 Acyltransferase CTP-dep_RFKase PF01982.16 CEH17773.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF120 ASF1_hist_chap PF04729.13 CEH17774.1 - 3.4e-68 228.4 0.0 4.1e-68 228.2 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Kinesin PF00225.23 CEH17775.1 - 2.8e-110 368.4 0.3 3.9e-110 367.9 0.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 CEH17775.1 - 8e-40 136.9 9.6 4.2e-33 115.0 0.9 3.3 2 1 1 3 3 3 2 Kinesin-associated DUF3694 PF12473.8 CEH17775.1 - 1.8e-36 126.1 0.0 4.8e-36 124.7 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 CEH17775.1 - 9.9e-27 93.7 0.0 9.9e-27 93.7 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 CEH17775.1 - 8.3e-13 48.8 0.0 1.7e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 PH domain KIF1B PF12423.8 CEH17775.1 - 1.7e-06 28.3 0.0 4.9e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 CEH17775.1 - 2.6e-06 27.7 0.0 1.2e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 FHA domain EAP30 PF04157.16 CEH17775.1 - 0.078 12.3 0.3 0.31 10.3 0.1 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family Peroxin-3 PF04882.12 CEH17776.1 - 6.7e-120 401.2 0.0 1.9e-118 396.5 0.0 2.2 1 1 0 1 1 1 1 Peroxin-3 TFIIA PF03153.13 CEH17776.1 - 0.17 11.8 11.1 0.27 11.2 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3934 PF13070.6 CEH17776.1 - 0.22 12.0 0.6 0.56 10.7 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) BTG PF07742.12 CEH17777.1 - 4.6e-17 61.9 0.0 7.8e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 BTG family DASH_Spc34 PF08657.10 CEH17777.1 - 0.17 11.7 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 Septin PF00735.18 CEH17779.1 - 6.7e-121 402.9 0.1 1.1e-120 402.2 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CEH17779.1 - 2.3e-08 34.1 0.1 6.7e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEH17779.1 - 5.5e-07 29.6 0.1 5.9e-05 23.0 0.0 2.8 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CEH17779.1 - 0.00016 21.8 1.5 0.037 14.1 0.0 3.0 2 1 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 CEH17779.1 - 0.0006 19.4 3.1 0.0097 15.5 0.0 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CEH17779.1 - 0.0018 18.5 0.4 0.01 16.1 0.0 2.4 3 1 0 3 3 3 1 AAA domain Ras PF00071.22 CEH17779.1 - 0.0021 17.7 0.0 0.018 14.6 0.0 2.4 2 0 0 2 2 2 1 Ras family AIG1 PF04548.16 CEH17779.1 - 0.0047 16.3 0.3 0.016 14.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 CEH17779.1 - 0.012 16.1 7.1 0.022 15.3 0.5 2.8 1 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 CEH17779.1 - 0.015 15.7 0.1 0.046 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CEH17779.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 CEH17779.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Exonuc_VII_L PF02601.15 CEH17779.1 - 0.11 12.0 6.4 0.17 11.4 6.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 CEH17779.1 - 0.19 11.5 2.0 9.1 6.0 0.0 3.2 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.6 CEH17779.1 - 1.7 8.4 5.4 1.6 8.5 3.4 1.8 2 0 0 2 2 2 0 AAA domain Strep_SA_rep PF06696.11 CEH17779.1 - 1.9 8.6 7.9 0.49 10.5 0.6 2.5 2 0 0 2 2 2 0 Streptococcal surface antigen repeat ABC_tran PF00005.27 CEH17780.1 - 7.7e-47 159.3 0.0 4.6e-28 98.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CEH17780.1 - 3.5e-36 125.3 13.3 1.1e-25 90.9 1.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CEH17780.1 - 3.4e-08 33.2 0.4 0.11 12.0 0.2 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEH17780.1 - 2.9e-07 30.1 1.5 0.015 15.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CEH17780.1 - 8.4e-07 29.1 2.6 0.044 13.6 0.1 4.2 3 2 1 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CEH17780.1 - 4.3e-06 27.1 0.1 0.00059 20.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CEH17780.1 - 7.5e-05 22.8 0.1 0.11 12.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CEH17780.1 - 0.0017 18.4 0.5 0.41 10.7 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 CEH17780.1 - 0.0017 18.7 4.4 0.015 15.7 0.4 3.2 2 1 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 CEH17780.1 - 0.0019 18.7 0.1 1.5 9.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CEH17780.1 - 0.0069 16.3 0.2 0.47 10.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 CEH17780.1 - 0.0069 16.1 0.0 3.2 7.4 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CEH17780.1 - 0.0072 15.9 1.4 2.1 7.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 CEH17780.1 - 0.009 15.8 0.0 0.03 14.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain T2SSE PF00437.20 CEH17780.1 - 0.011 14.8 0.2 3 6.8 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 CEH17780.1 - 0.016 14.5 0.8 1.8 7.8 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_33 PF13671.6 CEH17780.1 - 0.02 15.0 0.1 5 7.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 CEH17780.1 - 0.034 14.4 0.2 0.62 10.3 0.1 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CEH17780.1 - 0.038 13.7 0.0 0.19 11.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 CEH17780.1 - 0.063 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_ATPase PF09818.9 CEH17780.1 - 0.073 11.9 0.6 2.2 7.0 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NTPase_1 PF03266.15 CEH17780.1 - 0.097 12.6 0.0 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 NTPase Pox_A32 PF04665.12 CEH17780.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.14 CEH17780.1 - 0.2 11.5 0.2 0.78 9.6 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.18 CEH17780.1 - 0.21 10.8 0.0 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Septin NB-ARC PF00931.22 CEH17780.1 - 0.58 9.3 2.2 2.2 7.4 0.6 2.7 2 1 0 2 2 2 0 NB-ARC domain DUF3593 PF12159.8 CEH17780.1 - 5 7.2 6.4 3.6 7.7 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3593) Skp1 PF01466.19 CEH17781.1 - 6.8e-30 102.9 0.4 1.5e-29 101.8 0.4 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CEH17781.1 - 5.2e-23 81.0 0.2 1.4e-22 79.6 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 CEH17781.1 - 0.011 16.0 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain RhoGEF PF00621.20 CEH17782.1 - 6.7e-33 114.5 0.1 1.4e-32 113.4 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 CEH17782.1 - 2.8e-16 58.9 0.9 1.2e-07 31.2 0.1 2.6 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.7 CEH17782.1 - 1.6e-15 56.9 0.0 4.6e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_9 PF14604.6 CEH17782.1 - 4.2e-14 52.1 1.0 1.7e-07 31.0 0.1 2.9 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.20 CEH17782.1 - 1.4e-08 34.3 0.9 3.5e-08 33.0 0.9 1.7 1 0 0 1 1 1 1 WH2 motif SH3_2 PF07653.17 CEH17782.1 - 3.7e-06 26.5 0.0 0.023 14.3 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PH_13 PF16652.5 CEH17782.1 - 7.9e-06 25.8 0.0 2.5e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain UIM PF02809.20 CEH17782.1 - 0.11 12.5 4.5 0.95 9.5 0.8 3.3 2 0 0 2 2 2 0 Ubiquitin interaction motif HTH_9 PF08221.11 CEH17784.1 - 9.1e-16 57.7 6.2 6.7e-08 32.5 0.0 4.4 5 0 0 5 5 5 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 CEH17784.1 - 8.1e-11 42.2 0.0 2.7e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 CEH17784.1 - 7.5e-09 35.4 0.4 1.6e-07 31.2 0.3 3.0 3 0 0 3 3 3 1 TFIIE alpha subunit ERG4_ERG24 PF01222.17 CEH17785.1 - 3.9e-143 477.3 6.6 4.5e-143 477.1 6.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CEH17785.1 - 0.00014 21.4 0.1 0.00028 20.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CEH17785.1 - 0.0043 17.4 1.9 0.012 16.0 0.0 2.7 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 CEH17785.1 - 0.011 16.1 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Med17 PF10156.9 CEH17786.1 - 6.6e-12 44.9 7.6 1.2e-05 24.2 0.0 2.9 3 1 0 3 3 3 2 Subunit 17 of Mediator complex Hist_deacetyl PF00850.19 CEH17787.1 - 6.5e-84 282.0 0.0 9.8e-84 281.4 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Actin PF00022.19 CEH17788.1 - 1.1e-147 492.0 0.0 5.1e-147 489.7 0.0 1.8 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 CEH17788.1 - 0.003 16.2 0.0 0.0042 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase eIF3g PF12353.8 CEH17789.1 - 0.26 11.7 2.1 0.29 11.5 1.4 1.7 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Bud13 PF09736.9 CEH17790.1 - 3.7e-36 124.7 1.8 4.3e-36 124.5 1.8 1.1 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex HAT PF02184.16 CEH17791.1 - 7e-16 57.9 59.2 4.4e-08 32.9 1.6 13.6 14 1 0 14 14 14 3 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 CEH17791.1 - 5.8e-15 54.7 36.8 3e-05 24.5 0.4 11.5 5 2 7 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 CEH17791.1 - 1.6e-14 54.2 4.1 8.8e-07 29.4 0.0 6.4 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEH17791.1 - 2.3e-08 33.5 4.6 0.023 14.8 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CEH17791.1 - 4.1e-06 26.8 14.4 0.15 12.0 0.1 6.9 6 2 0 6 6 6 2 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 CEH17791.1 - 5e-06 27.1 2.3 0.00022 21.8 0.1 6.7 5 2 3 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEH17791.1 - 1.6e-05 24.7 0.3 0.16 12.3 0.1 5.7 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEH17791.1 - 0.0013 18.9 0.1 1.6 9.2 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEH17791.1 - 0.011 15.4 0.0 1.7 8.4 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_15 PF13429.6 CEH17791.1 - 0.016 14.5 31.1 0.17 11.1 0.4 5.9 3 2 4 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEH17791.1 - 0.018 15.2 16.7 0.036 14.2 0.9 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEH17791.1 - 0.019 14.8 0.1 9.8 6.2 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEH17791.1 - 0.11 12.6 0.0 12 6.1 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 CEH17791.1 - 0.98 9.6 9.0 10 6.4 0.0 5.9 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEH17791.1 - 3.3 8.5 14.7 76 4.3 0.0 7.5 7 1 0 7 7 7 0 Tetratricopeptide repeat LCM PF04072.14 CEH17792.1 - 1.4e-18 67.5 0.0 2.1e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PMT PF02366.18 CEH17793.1 - 9.9e-79 264.4 13.0 9.9e-79 264.4 13.0 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CEH17793.1 - 7.8e-62 208.4 8.5 7.8e-62 208.4 8.5 1.9 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CEH17793.1 - 6.7e-37 127.1 0.0 1.8e-36 125.7 0.0 1.7 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.6 CEH17793.1 - 6e-05 23.3 10.3 6e-05 23.3 10.3 3.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Mito_carr PF00153.27 CEH17794.1 - 2.1e-46 155.8 0.8 6.8e-16 58.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2258 PF10015.9 CEH17795.1 - 0.079 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Utp21 PF04192.12 CEH17796.1 - 2.4e-18 66.5 0.0 4.1e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 CEH17796.1 - 1.1e-12 48.1 0.0 0.021 15.1 0.0 7.4 3 2 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEH17796.1 - 2.3e-12 47.2 12.0 0.0046 17.8 0.0 7.4 8 1 0 8 8 8 4 WD domain, G-beta repeat Tti2 PF10521.9 CEH17796.1 - 1.3e-06 28.2 0.0 4.3e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Tti2 family VID27 PF08553.10 CEH17796.1 - 0.061 12.4 0.1 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Sugar_tr PF00083.24 CEH17798.1 - 9.6e-06 24.7 13.3 0.0043 16.0 6.8 3.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEH17798.1 - 0.00024 20.1 35.4 0.0079 15.2 21.6 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Carb_kinase PF01256.17 CEH17799.1 - 8.3e-43 146.6 0.0 9.6e-30 103.8 0.0 2.0 1 1 1 2 2 2 2 Carbohydrate kinase RIC1 PF07064.13 CEH17800.1 - 1e-51 175.8 0.0 1.6e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 CEH17800.1 - 0.012 15.8 0.0 0.077 13.3 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_sub6 PF10419.9 CEH17801.1 - 4.2e-13 49.0 0.0 6.8e-13 48.3 0.0 1.4 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain Presenilin PF01080.17 CEH17801.1 - 3.2 6.4 6.3 3.6 6.3 6.3 1.0 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 CEH17802.1 - 2.6e-23 81.8 12.0 0.0055 17.5 0.1 10.9 10 1 1 11 11 11 4 WD domain, G-beta repeat CTP_transf_like PF01467.26 CEH17802.1 - 3.5e-06 27.3 0.0 7.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like ANAPC4_WD40 PF12894.7 CEH17802.1 - 0.00026 21.2 1.5 18 5.7 0.2 5.7 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M17_N PF02789.17 CEH17802.1 - 0.054 13.3 1.4 0.63 9.9 0.2 3.0 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain MFS_1 PF07690.16 CEH17803.1 - 2.8e-13 49.5 22.8 2.8e-13 49.5 22.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Ost5 PF05251.12 CEH17803.1 - 0.0032 17.7 0.3 0.0032 17.7 0.3 3.2 4 0 0 4 4 4 1 Oligosaccharyltransferase subunit 5 UCH PF00443.29 CEH17804.1 - 5.3e-46 157.2 0.0 7.3e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEH17804.1 - 7.2e-24 84.9 0.7 2.4e-17 63.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CEH17804.1 - 0.00031 20.3 0.0 0.22 10.9 0.1 2.8 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF1104 PF06518.11 CEH17804.1 - 0.17 12.3 0.1 0.71 10.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) zf-AD PF07776.15 CEH17804.1 - 0.2 11.9 0.2 0.2 11.9 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) ING PF12998.7 CEH17805.1 - 1.3e-13 51.4 0.0 2.6e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CEH17805.1 - 0.00031 20.6 5.0 0.00049 19.9 5.0 1.3 1 0 0 1 1 1 1 PHD-finger Serglycin PF04360.12 CEH17805.1 - 0.00057 19.8 0.6 0.0014 18.6 0.6 1.7 1 0 0 1 1 1 1 Serglycin zf-C4pol PF14260.6 CEH17805.1 - 0.52 10.8 0.1 0.52 10.8 0.1 2.5 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta RNA_pol_A_bac PF01000.26 CEH17806.1 - 7.6e-26 90.7 0.0 2.2e-25 89.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CEH17806.1 - 2.5e-19 68.5 0.0 3.4e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-C2HC_2 PF13913.6 CEH17807.1 - 0.038 13.9 2.5 0.074 13.0 2.5 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 CEH17807.1 - 0.077 13.5 1.0 1.2 9.7 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain DUF3770 PF12603.8 CEH17808.1 - 0.11 12.0 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) Nucleoporin_FG2 PF15967.5 CEH17811.1 - 0.0053 15.4 1.0 0.0089 14.6 1.0 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeated region QslA_E PF18226.1 CEH17814.1 - 0.00045 20.1 0.0 0.00064 19.6 0.0 1.2 1 0 0 1 1 1 1 LasR-specific antiactivator QslA chain E NblA PF04485.12 CEH17816.1 - 0.013 15.9 0.4 0.022 15.2 0.4 1.3 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA Clathrin PF00637.20 CEH17819.1 - 2.5e-13 50.1 0.3 0.00017 21.5 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.8 CEH17819.1 - 1.4e-12 47.7 0.5 2.8e-12 46.7 0.5 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 CEH17819.1 - 5.7e-08 32.7 7.3 1.1e-07 31.7 7.3 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 CEH17819.1 - 0.00032 20.5 7.0 0.00062 19.6 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEH17819.1 - 0.025 14.9 6.9 0.052 13.9 6.9 1.6 1 0 0 1 1 1 0 Ring finger domain TPR_2 PF07719.17 CEH17819.1 - 0.046 13.9 0.3 1.2 9.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_5 PF14634.6 CEH17819.1 - 0.075 13.0 6.8 0.14 12.1 6.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain TPR_16 PF13432.6 CEH17819.1 - 0.26 11.9 0.0 0.26 11.9 0.0 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 CEH17819.1 - 0.56 10.5 6.5 1.3 9.4 6.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CEH17819.1 - 2.9 8.0 6.9 6.2 6.9 6.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CEH17819.1 - 4.5 7.2 5.8 8.8 6.3 5.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3725 PF12523.8 CEH17820.1 - 0.00069 19.9 0.2 0.01 16.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3725) zf-C2HE PF16278.5 CEH17820.1 - 0.0056 17.1 0.4 0.6 10.6 0.0 2.7 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger SprT-like PF10263.9 CEH17820.1 - 0.043 13.7 0.7 0.085 12.7 0.3 1.7 2 0 0 2 2 2 0 SprT-like family zinc_ribbon_11 PF11682.8 CEH17820.1 - 0.23 11.5 2.6 9.7 6.2 0.1 2.6 2 1 0 2 2 2 0 Probable zinc-ribbon DUF3085 PF11284.8 CEH17822.1 - 0.016 15.5 0.9 0.11 12.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3085) SDA1 PF05285.12 CEH17826.1 - 0.18 11.2 14.7 0.29 10.5 14.7 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CEH17826.1 - 0.34 9.1 21.6 0.51 8.5 21.6 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 CEH17826.1 - 0.56 9.5 15.8 1.3 8.3 15.8 1.6 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 CEH17826.1 - 5.6 5.3 20.5 7.8 4.8 20.5 1.1 1 0 0 1 1 1 0 Mpp10 protein NAD_kinase PF01513.21 CEH17827.1 - 1.6e-21 76.7 0.0 7.3e-21 74.6 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CEH17827.1 - 0.17 11.5 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 CEH17828.1 - 4.2e-44 150.9 0.3 9.9e-44 149.7 0.0 1.7 2 0 0 2 2 2 1 ATP-NAD kinase Torus PF16131.5 CEH17829.1 - 1.1e-08 35.8 0.2 2.8e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 CEH17829.1 - 4.8e-07 29.6 4.2 1.2e-06 28.4 4.2 1.7 1 0 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 CEH17829.1 - 2e-06 27.5 0.0 4.4e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 CEH17829.1 - 0.00015 21.5 2.5 0.00015 21.5 2.5 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEH17829.1 - 0.00036 20.3 3.6 0.00077 19.2 3.6 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CEH17829.1 - 0.00045 20.4 0.2 0.0011 19.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger containing family RRM_occluded PF16842.5 CEH17829.1 - 0.0069 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif FYVE PF01363.21 CEH17829.1 - 0.021 15.0 0.3 0.021 15.0 0.3 2.0 3 0 0 3 3 3 0 FYVE zinc finger zf-CCCH_2 PF14608.6 CEH17829.1 - 0.44 11.1 6.7 0.086 13.3 2.7 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger CAP PF00188.26 CEH17830.1 - 0.17 12.7 0.8 0.43 11.4 0.1 2.0 2 0 0 2 2 2 0 Cysteine-rich secretory protein family Arm PF00514.23 CEH17832.1 - 0.062 13.4 7.8 2.4 8.3 0.2 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 CEH17832.1 - 0.2 11.6 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) zf-rbx1 PF12678.7 CEH17833.1 - 1.2e-09 38.3 7.7 2e-09 37.6 7.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEH17833.1 - 2.8e-08 34.0 10.8 2.4e-07 31.0 10.8 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEH17833.1 - 8.5e-07 28.7 5.7 1.4e-06 28.1 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEH17833.1 - 4.6e-06 26.4 5.1 1e-05 25.3 5.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEH17833.1 - 8.6e-06 25.7 1.3 1.6e-05 24.8 1.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CEH17833.1 - 0.0001 22.0 3.8 0.0001 22.0 3.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH17833.1 - 0.00028 20.8 5.5 0.00051 20.0 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEH17833.1 - 0.00056 19.9 1.9 0.0011 18.9 1.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEH17833.1 - 0.0018 18.1 8.4 0.011 15.6 8.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEH17833.1 - 0.0083 15.8 1.4 0.0083 15.8 1.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CEH17833.1 - 0.025 14.7 1.4 0.057 13.6 1.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CEH17833.1 - 0.15 11.9 0.3 0.35 10.7 0.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 CEH17833.1 - 0.18 11.5 4.6 0.72 9.5 5.2 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_9 PF13901.6 CEH17833.1 - 0.24 11.4 2.6 0.38 10.7 2.6 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-C3H2C3 PF17122.5 CEH17833.1 - 0.38 10.8 2.6 0.75 9.9 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 CEH17833.1 - 0.42 11.0 3.0 0.92 9.9 3.0 1.5 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 CEH17833.1 - 5.9 7.1 5.7 17 5.7 5.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Aldedh PF00171.22 CEH17834.1 - 1.9e-127 425.6 0.0 2.3e-127 425.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 CEH17834.1 - 0.0024 17.0 0.0 0.0066 15.5 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Ferric_reduct PF01794.19 CEH17837.1 - 5.8e-19 68.4 12.4 5.8e-19 68.4 12.4 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEH17837.1 - 5.7e-17 62.3 0.0 1e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEH17837.1 - 5.7e-15 55.3 0.0 5.4e-14 52.2 0.0 2.4 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 CEH17837.1 - 0.0013 19.4 0.0 0.29 11.8 0.0 2.5 1 1 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF2070 PF09843.9 CEH17837.1 - 4.4 5.5 10.3 8.6 4.5 10.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GNAT_C PF18164.1 CEH17838.1 - 0.032 13.9 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 GNAT-like C-terminal domain WD40 PF00400.32 CEH17839.1 - 2e-49 164.5 20.5 1e-09 38.8 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH17839.1 - 6.9e-16 58.3 0.8 0.00043 20.5 0.0 5.6 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEH17839.1 - 2.7e-08 32.9 7.1 0.14 10.8 0.1 5.6 2 2 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CEH17839.1 - 1e-07 32.0 0.0 0.0027 17.6 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEH17839.1 - 0.0004 19.8 0.0 0.04 13.3 0.0 3.4 2 1 3 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 CEH17839.1 - 0.0035 16.4 0.1 7.8 5.4 0.0 3.6 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CEH17839.1 - 0.0074 15.3 1.7 0.21 10.5 0.0 3.4 2 1 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 CEH17839.1 - 0.03 12.6 0.1 0.061 11.6 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 CEH17839.1 - 0.1 11.6 0.2 0.3 10.1 0.0 1.8 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain Kelch_6 PF13964.6 CEH17839.1 - 0.13 12.6 0.1 2.9 8.3 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Nbas_N PF15492.6 CEH17839.1 - 0.4 10.0 2.9 4.5 6.5 0.1 3.0 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Molybdopterin PF00384.22 CEH17840.1 - 2.5e-66 224.4 0.0 1.6e-65 221.8 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 CEH17840.1 - 3.6e-18 65.4 0.2 1.2e-17 63.7 0.2 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 CEH17840.1 - 3.9e-16 59.5 0.1 1.4e-15 57.7 0.1 2.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 CEH17840.1 - 4.5e-16 58.1 0.1 4.5e-16 58.1 0.1 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 CEH17840.1 - 3.6e-07 30.0 1.2 3.6e-07 30.0 1.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 CEH17840.1 - 0.0026 17.5 0.0 0.055 13.2 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 CEH17840.1 - 0.17 11.7 1.3 4.6 7.2 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.23 CEH17841.1 - 4.9e-60 203.1 0.1 2.8e-59 200.6 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEH17841.1 - 4e-18 65.8 0.2 1.5e-17 64.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH17841.1 - 7.9e-10 39.0 0.2 6.4e-08 32.8 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CEH17841.1 - 0.0019 17.4 2.8 0.002 17.3 0.0 2.4 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DBINO PF13892.6 CEH17841.1 - 0.0029 18.0 0.9 0.0029 18.0 0.9 2.9 3 1 1 4 4 4 1 DNA-binding domain Hamartin PF04388.12 CEH17841.1 - 0.78 8.3 7.6 1.4 7.5 7.6 1.3 1 0 0 1 1 1 0 Hamartin protein PSII_Pbs31 PF18240.1 CEH17841.1 - 1 9.8 6.7 0.065 13.7 0.6 2.1 2 0 0 2 2 2 0 Photosystem II Psb31 protein AhpC-TSA_2 PF13911.6 CEH17842.1 - 6.8e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme HAD PF12710.7 CEH17842.1 - 0.02 15.3 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SSF PF00474.17 CEH17844.1 - 4.9e-19 68.5 22.8 8.8e-19 67.6 22.8 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Orf78 PF06024.12 CEH17844.1 - 0.11 12.8 1.2 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) ETRAMP PF09716.10 CEH17844.1 - 1.7 8.7 6.6 78 3.4 0.4 3.8 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Zn_clus PF00172.18 CEH17845.1 - 7.9e-08 32.3 6.7 2.6e-07 30.7 6.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MaoC_dehydratas PF01575.19 CEH17846.1 - 1.2e-26 92.7 0.0 2.8e-26 91.5 0.0 1.6 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CEH17846.1 - 2.9e-05 24.2 0.0 0.004 17.3 0.0 2.5 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase Rad21_Rec8_N PF04825.13 CEH17847.1 - 8.1e-27 93.6 0.0 1.4e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CEH17847.1 - 8.4e-12 44.2 0.0 1.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 CEH17847.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Dynamitin PF04912.14 CEH17848.1 - 6.4e-61 206.8 2.6 6.4e-61 206.8 2.6 1.6 2 0 0 2 2 2 1 Dynamitin Golgin_A5 PF09787.9 CEH17848.1 - 0.13 11.7 9.7 1.6 8.1 4.1 2.9 2 1 1 3 3 3 0 Golgin subfamily A member 5 UCMA PF17085.5 CEH17848.1 - 0.92 9.5 6.8 1.2 9.1 5.1 2.0 2 0 0 2 2 2 0 Unique cartilage matrix associated protein DUF4140 PF13600.6 CEH17848.1 - 4.8 7.7 9.9 29 5.2 0.0 4.3 4 1 1 5 5 5 0 N-terminal domain of unknown function (DUF4140) Ndc1_Nup PF09531.10 CEH17849.1 - 0.0034 16.2 2.3 0.0058 15.4 2.3 1.4 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF5427 PF10310.9 CEH17849.1 - 0.87 8.5 8.1 1.3 7.9 8.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4834 PF16118.5 CEH17849.1 - 2 9.4 4.7 5.5 8.0 4.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4614 PF15391.6 CEH17849.1 - 2.3 8.2 23.4 4.2 7.3 23.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 CEH17849.1 - 3.9 6.2 15.0 5.4 5.7 15.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pex14_N PF04695.13 CEH17849.1 - 8.1 7.1 16.8 0.59 10.8 10.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CEH17849.1 - 9.3 4.9 7.8 14 4.3 7.8 1.2 1 0 0 1 1 1 0 Presenilin Polysacc_deac_1 PF01522.21 CEH17850.1 - 6.7e-24 84.2 0.0 1.2e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEH17850.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 ThuA PF06283.11 CEH17851.1 - 1.2e-42 146.5 0.0 1.5e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation Varsurf_PPLC PF03490.13 CEH17853.1 - 0.016 15.2 0.2 0.048 13.6 0.2 1.8 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C PI-PLC-C1 PF16670.5 CEH17853.1 - 0.084 11.9 0.6 2.3 7.2 0.0 2.3 1 1 1 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent Mso1_C PF14477.6 CEH17853.1 - 9.9 6.7 11.2 2.4 8.6 0.7 3.5 3 0 0 3 3 3 0 Membrane-polarising domain of Mso1 NAD_binding_1 PF00175.21 CEH17854.1 - 3.8e-26 91.9 0.0 5.8e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CEH17854.1 - 7.2e-18 64.8 0.0 1.3e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CEH17854.1 - 8.9e-06 25.9 0.0 0.0012 19.0 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CEH17854.1 - 0.023 14.9 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Tristanin_u2 PF16638.5 CEH17856.1 - 0.029 15.2 0.9 0.07 14.0 0.9 1.6 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers PUF PF00806.19 CEH17860.1 - 1.9e-49 162.6 0.5 7.2e-08 31.7 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat CPL PF08144.11 CEH17860.1 - 0.027 14.8 1.2 7.2 6.9 0.1 4.1 1 1 2 4 4 4 0 CPL (NUC119) domain Glyco_hydro_47 PF01532.20 CEH17862.1 - 8.1e-149 496.4 0.0 1e-148 496.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 CEH17862.1 - 0.077 12.5 0.8 8.4 5.8 0.1 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 Glyco_hydro_43 PF04616.14 CEH17863.1 - 9.4e-14 51.4 2.3 9.4e-14 51.4 2.3 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 43 Ssl1 PF04056.14 CEH17864.1 - 7.3e-67 224.9 0.0 1.6e-66 223.8 0.0 1.5 1 0 0 1 1 1 1 Ssl1-like Nup160 PF11715.8 CEH17864.1 - 7.1e-28 97.6 0.0 2.5e-25 89.1 0.0 2.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 VWA_2 PF13519.6 CEH17864.1 - 4.7e-14 52.9 0.1 1.6e-12 48.0 0.0 3.2 3 0 0 3 3 3 1 von Willebrand factor type A domain GST_C_3 PF14497.6 CEH17865.1 - 4.9e-09 36.3 0.0 1.5e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEH17865.1 - 2.6e-07 30.7 0.0 5.7e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEH17865.1 - 4.3e-07 29.9 0.4 1.6e-06 28.0 0.2 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CEH17865.1 - 0.00012 22.4 0.0 0.00025 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CEH17865.1 - 0.033 14.0 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SPA PF08616.10 CEH17866.1 - 1.9e-31 108.4 0.0 3e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 CEH17866.1 - 6.4e-22 78.5 0.4 2.2e-20 73.5 0.4 2.3 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 CEH17866.1 - 2.4e-05 23.2 0.0 0.017 13.8 0.0 2.4 2 0 0 2 2 2 2 Transport protein Avl9 Arrestin_N PF00339.29 CEH17867.1 - 5.1e-06 26.6 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DRIM PF07539.12 CEH17868.1 - 1.7e-172 575.0 7.7 1.8e-172 574.9 0.2 3.8 4 0 0 4 4 4 1 Down-regulated in metastasis DUF3385 PF11865.8 CEH17868.1 - 0.0019 18.2 1.2 1.2 9.0 0.0 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) DUF3361 PF11841.8 CEH17868.1 - 0.0081 16.1 0.1 0.087 12.8 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Lambda_CIII PF02061.16 CEH17868.1 - 0.13 12.3 0.0 0.64 10.1 0.0 2.2 1 0 0 1 1 1 0 Lambda Phage CIII HEAT PF02985.22 CEH17868.1 - 5.9 7.4 12.3 3.2 8.3 0.2 5.9 6 0 0 6 6 6 0 HEAT repeat SAE2 PF08573.10 CEH17869.1 - 5.3 8.2 7.5 12 7.0 0.3 3.4 3 0 0 3 3 3 0 DNA repair protein endonuclease SAE2/CtIP C-terminus PBP PF01161.20 CEH17873.1 - 4.3e-07 30.3 0.0 6.2e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SHOCT PF09851.9 CEH17873.1 - 0.052 13.3 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Short C-terminal domain RXLR PF16810.5 CEH17873.1 - 0.11 12.9 1.0 0.12 12.8 0.1 1.4 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Arf PF00025.21 CEH17874.1 - 5e-66 221.5 0.0 5.6e-66 221.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CEH17874.1 - 2.8e-10 39.9 0.0 1.1e-06 28.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CEH17874.1 - 3.7e-09 36.3 0.0 4.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CEH17874.1 - 1.4e-07 31.2 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH17874.1 - 2.3e-07 31.0 0.0 5.8e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CEH17874.1 - 5.2e-07 29.8 0.0 7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEH17874.1 - 0.00011 21.7 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEH17874.1 - 0.014 15.0 0.1 0.37 10.3 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CEH17874.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.8 CEH17874.1 - 0.19 10.9 0.0 0.82 8.8 0.0 1.8 2 0 0 2 2 2 0 Centromere protein M (CENP-M) MFS_1 PF07690.16 CEH17875.1 - 1.5e-19 70.2 31.3 1.6e-16 60.2 14.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CEH17875.1 - 6.4e-19 68.4 8.1 1.9e-18 66.9 3.2 2.4 2 0 0 2 2 2 2 Nodulin-like DUF3392 PF11872.8 CEH17875.1 - 0.93 9.8 8.3 5.1 7.4 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3392) GFO_IDH_MocA PF01408.22 CEH17876.1 - 1.7e-11 45.0 1.3 1.6e-10 41.8 1.3 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 CEH17876.1 - 0.028 14.9 0.0 0.099 13.1 0.0 1.8 2 0 0 2 2 2 0 CoA binding domain Sugar_tr PF00083.24 CEH17877.1 - 7.9e-77 259.0 10.2 1.2e-55 189.2 1.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEH17877.1 - 1e-12 47.7 28.9 5.6e-12 45.2 29.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CEH17877.1 - 0.0013 17.3 0.2 0.0018 16.7 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LSM PF01423.22 CEH17878.1 - 1.3e-14 53.6 0.0 1.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEH17878.1 - 0.0081 16.3 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 CEH17878.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain DUF2733 PF10813.8 CEH17880.1 - 0.19 11.5 0.2 0.36 10.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) DnaJ PF00226.31 CEH17882.1 - 4.6e-22 77.9 0.4 8e-22 77.1 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain WLM PF08325.10 CEH17882.1 - 0.54 10.3 5.0 1.5 8.8 5.0 1.8 1 1 0 1 1 1 0 WLM domain DUF4880 PF16220.5 CEH17883.1 - 0.016 15.0 1.4 0.054 13.4 1.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) AA_permease_2 PF13520.6 CEH17885.1 - 1.6e-57 195.3 38.9 1.9e-57 195.0 38.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEH17885.1 - 3.7e-26 91.8 33.4 4.6e-26 91.4 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease Ferric_reduct PF01794.19 CEH17886.1 - 1.7e-15 57.3 9.5 4.4e-15 55.9 9.5 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CEH17886.1 - 1.3e-14 54.2 0.0 2.9e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CEH17886.1 - 8.9e-11 42.1 0.0 1e-08 35.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Polysacc_deac_1 PF01522.21 CEH17887.1 - 6.3e-27 93.9 0.0 1e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase HAMP PF00672.25 CEH17888.1 - 1.1e-38 131.4 16.5 5.5e-08 33.1 0.1 9.1 8 2 1 9 9 9 6 HAMP domain HATPase_c PF02518.26 CEH17888.1 - 2.6e-27 95.5 0.0 1.3e-26 93.3 0.0 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CEH17888.1 - 1.5e-25 89.5 1.3 3.3e-23 82.0 0.6 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 CEH17888.1 - 2e-16 59.8 2.2 2.3e-15 56.4 0.3 4.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Rab5-bind PF09311.11 CEH17888.1 - 0.035 13.5 8.4 0.96 8.8 0.0 4.3 3 2 0 3 3 3 0 Rabaptin-like protein TMF_TATA_bd PF12325.8 CEH17888.1 - 0.2 11.9 5.0 7.1 6.9 0.0 4.3 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF3829 PF12889.7 CEH17888.1 - 1 8.8 4.2 10 5.5 0.0 3.8 3 1 0 4 4 4 0 Protein of unknown function (DUF3829) SpoIIID PF12116.8 CEH17888.1 - 3 8.0 4.3 27 4.9 0.0 4.2 6 0 0 6 6 6 0 Stage III sporulation protein D ALS_ss_C PF10369.9 CEH17890.1 - 1.7e-19 69.8 0.1 2.7e-17 62.7 0.0 2.3 2 0 0 2 2 2 2 Small subunit of acetolactate synthase DUF2187 PF09953.9 CEH17890.1 - 0.071 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) DnaJ_C PF01556.18 CEH17891.1 - 4.9e-42 143.5 0.3 6.6e-42 143.1 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEH17891.1 - 2.1e-21 75.8 0.2 3.5e-21 75.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEH17891.1 - 1.3e-14 54.3 19.5 2.4e-14 53.4 19.5 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CEH17891.1 - 0.013 15.5 11.0 0.038 13.9 1.0 2.8 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein SUV3_C PF12513.8 CEH17891.1 - 0.056 13.4 0.0 54 3.8 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial degradasome RNA helicase subunit C terminal HypA PF01155.19 CEH17891.1 - 5.5 7.1 11.2 8.5 6.4 3.1 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 CEH17891.1 - 5.6 6.6 7.6 1.1 8.8 1.8 2.1 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Aconitase PF00330.20 CEH17892.1 - 5.7e-146 487.1 0.0 8.7e-146 486.5 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEH17892.1 - 1.1e-30 106.6 0.0 2.4e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.9 CEH17892.1 - 5.2e-07 29.9 5.0 3.7e-06 27.2 0.4 2.9 3 0 0 3 3 3 1 Mitochondrial ribosomal protein L28 DUF2514 PF10721.9 CEH17893.1 - 1.8 8.6 13.5 0.039 14.0 5.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) DUF572 PF04502.13 CEH17893.1 - 1.8 8.1 10.9 2.6 7.6 10.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) PIEZO PF15917.5 CEH17893.1 - 2.5 7.5 8.9 0.5 9.8 4.3 1.9 2 0 0 2 2 2 0 Piezo RNA_pol_Rpb6 PF01192.22 CEH17894.1 - 2.6e-18 65.7 0.1 3.8e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF4549 PF15082.6 CEH17894.1 - 0.21 11.3 0.0 0.29 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Pro_isomerase PF00160.21 CEH17895.1 - 1.9e-50 171.2 0.0 2.2e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HATPase_c PF02518.26 CEH17896.1 - 8.9e-18 64.8 0.2 2.3e-17 63.5 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CEH17896.1 - 1.2e-15 57.7 0.0 4.6e-10 39.7 0.0 2.9 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 CEH17896.1 - 2.8e-15 56.1 0.0 9.1e-15 54.5 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Na_H_Exchanger PF00999.21 CEH17897.1 - 5.5e-55 186.7 48.9 7.6e-55 186.2 48.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3445 PF11927.8 CEH17898.1 - 1.3e-40 139.5 0.0 9.7e-40 136.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) EPSP_synthase PF00275.20 CEH17901.1 - 2.2e-96 323.1 2.1 2.4e-96 323.0 2.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) RTC PF01137.21 CEH17901.1 - 0.026 13.7 0.0 0.24 10.6 0.0 2.3 1 1 1 2 2 2 0 RNA 3'-terminal phosphate cyclase EAP30 PF04157.16 CEH17903.1 - 5e-58 196.2 0.0 6.1e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Ish1 PF10281.9 CEH17904.1 - 1.6e-54 181.9 13.2 5.1e-10 39.5 0.2 6.9 7 0 0 7 7 7 6 Putative stress-responsive nuclear envelope protein 6PGD PF00393.19 CEH17904.1 - 0.00011 21.7 6.9 0.18 11.1 0.1 3.5 2 1 1 3 3 3 3 6-phosphogluconate dehydrogenase, C-terminal domain Peptidase_M19 PF01244.21 CEH17905.1 - 6.1e-94 314.8 0.0 7e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) E1_DerP2_DerF2 PF02221.15 CEH17906.1 - 9.4e-27 94.1 0.1 1.3e-26 93.6 0.1 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 CEH17906.1 - 0.0019 18.6 0.0 0.03 14.7 0.0 2.1 1 1 1 2 2 2 1 ML-like domain Pdase_C33_assoc PF14756.6 CEH17906.1 - 0.11 12.5 0.6 0.3 11.0 0.6 1.8 1 0 0 1 1 1 0 Peptidase_C33-associated domain GTP_EFTU PF00009.27 CEH17907.1 - 4e-33 114.6 0.0 1.9e-32 112.4 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CEH17907.1 - 2.3e-14 53.5 4.2 5.2e-10 39.6 0.3 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF-2 PF11987.8 CEH17907.1 - 3.2e-13 49.7 0.0 9.5e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CEH17907.1 - 1.2e-05 25.4 0.0 5e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CEH17907.1 - 8.3e-05 22.4 0.0 0.00024 20.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 CEH17907.1 - 0.0037 17.5 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CEH17907.1 - 0.014 15.1 0.0 0.045 13.5 0.0 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DDE_2 PF02914.15 CEH17907.1 - 0.18 11.5 3.3 0.4 10.4 3.3 1.5 1 0 0 1 1 1 0 Bacteriophage Mu transposase Pkinase PF00069.25 CEH17908.1 - 1.8e-53 181.6 0.0 3.5e-48 164.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH17908.1 - 1e-34 120.0 0.0 1.1e-30 106.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH17908.1 - 0.00012 21.0 1.5 0.00023 20.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CEH17908.1 - 0.00026 20.4 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 CEH17908.1 - 0.0011 18.1 0.2 0.0019 17.2 0.2 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 CEH17908.1 - 0.0078 16.2 0.9 0.12 12.2 0.1 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CEH17908.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 CEH17909.1 - 3.2e-05 23.7 0.6 8.3e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like WD40 PF00400.32 CEH17909.1 - 1.2 10.1 4.1 57 4.8 0.1 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat CoA_trans PF01144.23 CEH17911.1 - 2.5e-99 331.0 0.4 2.3e-60 203.7 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CEH17911.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 CEH17911.1 - 0.043 12.1 0.1 0.073 11.4 0.1 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter CD52 PF15116.6 CEH17911.1 - 2.4 8.3 4.4 25 5.0 0.9 2.7 2 0 0 2 2 2 0 CAMPATH-1 antigen BRAP2 PF07576.12 CEH17912.1 - 1.1e-23 83.3 0.1 2.9e-23 82.0 0.0 1.6 2 0 0 2 2 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CEH17912.1 - 7.1e-18 64.7 4.0 1.6e-17 63.5 4.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CEH17912.1 - 1.1e-07 32.0 9.3 3e-07 30.7 9.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEH17912.1 - 1.6e-06 27.9 8.7 4.6e-06 26.4 8.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEH17912.1 - 2.2e-05 24.7 5.1 6.1e-05 23.2 5.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain KASH_CCD PF14662.6 CEH17912.1 - 4.1e-05 23.5 7.7 6.4e-05 22.9 7.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-RING_UBOX PF13445.6 CEH17912.1 - 7.3e-05 22.7 3.1 0.00023 21.1 3.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEH17912.1 - 0.00018 21.3 6.9 0.00041 20.1 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEH17912.1 - 0.0006 19.5 4.2 0.0014 18.3 4.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CEH17912.1 - 0.0014 18.5 6.8 0.0014 18.5 6.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEH17912.1 - 0.0049 16.7 6.5 0.0049 16.7 6.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEH17912.1 - 0.0092 16.0 4.4 0.025 14.6 3.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger AIP3 PF03915.13 CEH17912.1 - 0.022 13.9 5.1 0.035 13.2 5.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 DUF4719 PF15843.5 CEH17912.1 - 0.053 13.6 0.7 0.11 12.6 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) zf-RING_4 PF14570.6 CEH17912.1 - 0.075 12.8 6.7 0.2 11.5 6.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C4 PF00105.18 CEH17912.1 - 0.19 12.2 3.0 0.47 10.9 3.0 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Lsr2 PF11774.8 CEH17912.1 - 0.32 11.1 2.3 0.56 10.4 1.2 2.0 1 1 1 2 2 2 0 Lsr2 Jnk-SapK_ap_N PF09744.9 CEH17912.1 - 0.35 11.1 9.7 0.76 10.0 9.7 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HALZ PF02183.18 CEH17912.1 - 1 9.6 3.7 0.63 10.3 1.4 1.7 2 0 0 2 2 1 0 Homeobox associated leucine zipper ATG16 PF08614.11 CEH17912.1 - 1.3 9.2 17.6 0.46 10.7 14.2 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BST2 PF16716.5 CEH17912.1 - 1.3 9.6 8.6 3.7 8.2 4.1 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF4407 PF14362.6 CEH17912.1 - 1.9 7.8 16.6 0.54 9.6 4.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 CEH17912.1 - 2.5 8.1 7.3 6.9 6.7 0.3 2.9 2 1 1 3 3 3 0 Prefoldin subunit FUSC PF04632.12 CEH17912.1 - 3.4 6.1 7.7 5.3 5.5 7.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sugarporin_N PF11471.8 CEH17912.1 - 5.4 7.0 6.9 0.5 10.4 0.6 2.6 3 0 0 3 3 2 0 Maltoporin periplasmic N-terminal extension GGACT PF06094.12 CEH17913.1 - 7e-10 39.6 0.0 1.9e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Dicistro_VP4 PF11492.8 CEH17913.1 - 0.14 12.1 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 RRM_1 PF00076.22 CEH17914.1 - 1.9e-18 66.0 0.0 2.7e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 CEH17914.1 - 4.5e-09 36.8 1.0 9.4e-09 35.8 1.0 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 CEH17914.1 - 0.0017 18.5 0.0 0.0044 17.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CEH17914.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chromo PF00385.24 CEH17915.1 - 0.0013 18.6 0.6 0.0024 17.8 0.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4196 PF13846.6 CEH17915.1 - 0.0076 16.4 3.7 0.019 15.1 3.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4196) TauD PF02668.16 CEH17916.1 - 6.4e-33 114.7 0.0 9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CEH17916.1 - 1.2e-13 51.5 0.0 1.1e-11 45.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF971) SHR3_chaperone PF08229.11 CEH17920.1 - 5.4e-40 136.4 0.0 6.5e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 OST3_OST6 PF04756.13 CEH17921.1 - 7.6e-86 288.1 0.1 1.1e-85 287.6 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 CEH17921.1 - 0.00065 19.6 0.0 0.0019 18.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Sec7_N PF12783.7 CEH17922.1 - 1e-40 139.2 0.3 9.2e-40 136.1 0.0 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CEH17922.1 - 3.7e-39 134.2 4.5 3.7e-39 134.2 4.5 1.9 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 CEH17922.1 - 1.9e-18 66.1 0.4 2.3e-11 42.7 0.3 3.5 3 0 0 3 3 3 3 C-terminal region of Mon2 protein Urb2 PF10441.9 CEH17922.1 - 8.8e-05 22.5 1.1 0.0005 20.1 0.2 2.9 3 0 0 3 3 3 1 Urb2/Npa2 family DUF1981 PF09324.10 CEH17922.1 - 0.0017 18.2 0.0 0.016 15.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) WD40 PF00400.32 CEH17923.1 - 4.7e-31 106.3 18.8 2.6e-06 28.0 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH17923.1 - 4.7e-13 49.2 0.4 0.0015 18.8 0.0 5.0 2 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEH17923.1 - 0.16 11.2 0.0 8.4 5.6 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain p450 PF00067.22 CEH17926.1 - 1.7e-22 79.8 0.0 2.2e-21 76.2 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 CEH17927.1 - 3.2e-22 79.0 0.1 3e-21 75.8 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH17927.1 - 7.2e-09 35.5 0.1 1.2e-07 31.5 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH17927.1 - 0.0035 17.3 0.1 0.017 15.0 0.1 1.8 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.17 CEH17927.1 - 0.0049 17.4 0.1 0.014 15.9 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CEH17927.1 - 0.0051 16.7 0.2 0.0091 15.9 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CEH17927.1 - 0.087 13.1 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 CEH17927.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HIG_1_N PF04588.13 CEH17928.1 - 1.5e-05 25.1 0.3 4.5e-05 23.6 0.3 1.9 1 0 0 1 1 1 1 Hypoxia induced protein conserved region CFEM PF05730.11 CEH17929.1 - 0.0004 20.4 10.8 0.00066 19.7 10.8 1.4 1 0 0 1 1 1 1 CFEM domain Secretin_N_2 PF07655.13 CEH17929.1 - 0.33 11.5 11.3 0.33 11.5 1.1 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain ODV-E18 PF10717.9 CEH17929.1 - 0.89 9.5 5.9 5.6 6.9 1.4 2.7 2 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Serglycin PF04360.12 CEH17929.1 - 9.9 6.1 7.4 6.3 6.7 0.4 2.3 2 0 0 2 2 2 0 Serglycin Sec3_C PF09763.9 CEH17930.1 - 1.5e-178 595.5 0.0 1.9e-178 595.1 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 CEH17930.1 - 2.9e-20 72.2 0.1 5.8e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 CEH17930.1 - 0.044 12.5 0.3 0.07 11.9 0.3 1.2 1 0 0 1 1 1 0 Vps52 / Sac2 family Tetraspanin PF00335.20 CEH17931.1 - 4.4e-11 42.9 2.7 6e-11 42.5 2.7 1.2 1 0 0 1 1 1 1 Tetraspanin family HMMR_N PF15905.5 CEH17933.1 - 1.7e-05 24.5 146.9 0.00032 20.3 23.9 6.4 2 1 4 6 6 6 4 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 CEH17933.1 - 0.00014 22.4 21.5 0.00014 22.4 21.5 10.6 2 2 8 11 11 11 2 Apg6 coiled-coil region Cnn_1N PF07989.11 CEH17933.1 - 0.00033 20.8 2.8 0.00033 20.8 2.8 12.4 8 2 4 12 12 11 2 Centrosomin N-terminal motif 1 FPP PF05911.11 CEH17933.1 - 0.00047 18.5 24.4 0.00047 18.5 24.4 5.8 2 1 3 5 5 5 3 Filament-like plant protein, long coiled-coil AAA_13 PF13166.6 CEH17933.1 - 0.00062 18.6 26.8 0.00062 18.6 26.8 5.6 2 1 4 6 6 5 1 AAA domain DHR10 PF18595.1 CEH17933.1 - 0.0012 18.9 15.1 0.0012 18.9 15.1 11.7 2 2 11 13 13 10 2 Designed helical repeat protein 10 domain Spc7 PF08317.11 CEH17933.1 - 0.0032 16.4 165.2 0.0067 15.4 24.4 9.5 2 2 8 10 10 10 8 Spc7 kinetochore protein Golgin_A5 PF09787.9 CEH17933.1 - 0.0032 17.0 22.0 0.0032 17.0 22.0 9.2 2 2 7 9 9 9 4 Golgin subfamily A member 5 ATG16 PF08614.11 CEH17933.1 - 0.0094 16.2 19.7 0.0094 16.2 19.7 9.0 2 2 6 8 8 7 3 Autophagy protein 16 (ATG16) ZapB PF06005.12 CEH17933.1 - 0.016 15.6 6.2 0.016 15.6 6.2 14.3 5 4 5 10 10 7 0 Cell division protein ZapB DUF812 PF05667.11 CEH17933.1 - 0.87 8.4 140.3 0.73 8.6 37.1 6.1 2 1 3 5 5 5 0 Protein of unknown function (DUF812) Fez1 PF06818.15 CEH17933.1 - 7 7.1 158.9 0.16 12.4 22.3 8.0 2 2 4 6 6 6 0 Fez1 LSM PF01423.22 CEH17934.1 - 4.5e-18 64.7 0.4 6.2e-18 64.3 0.4 1.2 1 0 0 1 1 1 1 LSM domain Propep_M14 PF02244.16 CEH17934.1 - 0.014 15.7 0.2 0.019 15.3 0.2 1.2 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Hfq PF17209.3 CEH17934.1 - 0.044 13.4 0.1 0.094 12.4 0.1 1.5 1 0 0 1 1 1 0 Hfq protein Asp_Glu_race PF01177.22 CEH17935.1 - 1.7e-08 34.6 0.1 2.7e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Allantoicase PF03561.15 CEH17936.1 - 1.9e-83 277.6 0.0 1.1e-40 138.9 0.0 2.4 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 CEH17936.1 - 3.2e-48 164.0 0.0 4.9e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase Transp_cyt_pur PF02133.15 CEH17938.1 - 5.5e-119 397.8 34.9 6.3e-119 397.6 34.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MotA_ExbB PF01618.16 CEH17938.1 - 0.19 11.5 1.2 1.6 8.5 1.1 2.4 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family WD40 PF00400.32 CEH17939.1 - 2e-29 101.2 5.5 0.00019 22.1 0.0 8.0 7 1 0 7 7 7 6 WD domain, G-beta repeat Prp19 PF08606.11 CEH17939.1 - 2.5e-29 101.0 0.4 4.2e-29 100.3 0.4 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 CEH17939.1 - 2.1e-15 56.8 0.0 0.085 13.2 0.0 5.9 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 CEH17939.1 - 0.0062 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain eIF2A PF08662.11 CEH17939.1 - 0.014 15.3 0.1 23 4.8 0.0 3.7 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEH17939.1 - 0.26 10.6 0.0 0.62 9.3 0.0 1.5 2 0 0 2 2 2 0 WD40-like domain Ribosomal_L27A PF00828.19 CEH17940.1 - 1.9e-36 125.6 0.1 2.9e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Hydrolase_4 PF12146.8 CEH17941.1 - 8e-15 54.7 0.0 1.9e-09 37.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH17941.1 - 2.2e-11 43.9 0.1 6.7e-08 32.5 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH17941.1 - 4.1e-06 27.6 0.3 5.9e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 CEH17941.1 - 8.6e-05 22.5 0.0 0.00025 21.1 0.0 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.12 CEH17941.1 - 0.00048 19.2 0.0 0.00068 18.7 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 CEH17941.1 - 0.0016 18.0 0.0 0.098 12.2 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 CEH17941.1 - 0.002 16.9 0.0 0.021 13.5 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 CEH17941.1 - 0.034 13.6 0.0 7.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 CEH17941.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) zf-RING_2 PF13639.6 CEH17942.1 - 2.2e-06 27.9 5.6 4.2e-06 27.0 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 CEH17942.1 - 9.2e-05 22.4 0.8 0.00018 21.5 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CEH17942.1 - 0.00029 21.1 3.9 0.00055 20.2 3.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain C1_1 PF00130.22 CEH17942.1 - 0.011 15.6 0.3 0.019 14.8 0.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.8 CEH17942.1 - 0.011 15.9 2.5 0.02 15.0 2.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.25 CEH17942.1 - 0.08 12.8 5.8 0.13 12.1 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2256 PF10013.9 CEH17942.1 - 0.11 12.7 0.5 0.25 11.5 0.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) RINGv PF12906.7 CEH17942.1 - 0.13 12.4 5.1 0.25 11.5 5.1 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CEH17942.1 - 0.21 11.9 1.6 0.44 10.9 1.6 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 CEH17942.1 - 0.29 11.0 3.0 0.55 10.1 3.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEH17942.1 - 0.33 10.8 7.9 0.77 9.6 7.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CEH17942.1 - 0.5 10.3 3.5 0.9 9.5 3.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 CEH17942.1 - 0.67 9.9 1.9 1.1 9.2 1.9 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PRCC PF10253.9 CEH17943.1 - 2e-05 25.5 44.1 3.2e-05 24.9 35.4 3.2 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Sec16_C PF12931.7 CEH17944.1 - 3.9e-93 312.4 0.0 5.5e-93 311.9 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CEH17944.1 - 5.9e-15 55.9 0.0 1.9e-14 54.2 0.0 2.0 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Rod_cone_degen PF15201.6 CEH17944.1 - 0.66 10.1 5.2 15 5.8 0.2 4.0 3 0 0 3 3 3 0 Progressive rod-cone degeneration CLN3 PF02487.17 CEH17945.1 - 9.2e-118 393.7 0.1 1.1e-117 393.5 0.1 1.0 1 0 0 1 1 1 1 CLN3 protein zf-RING_4 PF14570.6 CEH17947.1 - 2.2e-21 75.4 12.0 3.5e-21 74.7 12.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CEH17947.1 - 9.6e-07 28.6 9.3 1.6e-06 27.9 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEH17947.1 - 5.1e-05 23.0 9.2 0.0051 16.6 9.7 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 CEH17947.1 - 0.0016 18.3 0.0 0.0082 15.9 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 CEH17947.1 - 0.0032 17.8 12.1 0.0054 17.0 12.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-UDP PF14569.6 CEH17947.1 - 0.035 14.2 4.1 0.072 13.2 4.1 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 CEH17947.1 - 0.082 12.8 11.5 0.14 12.0 11.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nup35_RRM_2 PF14605.6 CEH17947.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.11 CEH17947.1 - 0.21 11.5 4.1 0.34 10.8 4.1 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 CEH17947.1 - 0.27 11.1 11.4 0.45 10.4 11.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEH17947.1 - 1.2 9.2 7.3 4.3 7.5 7.5 1.8 1 1 1 2 2 2 0 RING-type zinc-finger MAP65_ASE1 PF03999.12 CEH17947.1 - 1.7 7.3 8.8 0.57 8.8 2.7 2.1 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Rtf2 PF04641.12 CEH17947.1 - 6.6 6.0 9.2 6 6.1 2.3 2.5 2 0 0 2 2 2 0 Rtf2 RING-finger MMR_HSR1 PF01926.23 CEH17948.1 - 1.3e-16 60.7 0.0 2.3e-14 53.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEH17948.1 - 1.7e-07 31.3 0.0 0.00029 20.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CEH17948.1 - 5.3e-06 26.0 0.0 9.5e-05 22.0 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 CEH17948.1 - 0.024 14.0 0.0 0.024 14.0 0.0 2.0 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 CEH17948.1 - 0.04 13.5 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 CEH17948.1 - 0.041 13.9 0.0 0.041 13.9 0.0 2.5 2 1 1 3 3 3 0 Dynamin family AAA_15 PF13175.6 CEH17948.1 - 0.2 11.3 2.1 1.8 8.2 0.4 2.1 2 0 0 2 2 2 0 AAA ATPase domain RRN3 PF05327.11 CEH17948.1 - 0.29 9.6 1.8 0.42 9.1 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RR_TM4-6 PF06459.12 CEH17948.1 - 1.3 8.8 9.3 5 6.9 6.6 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 CEH17948.1 - 2.3 8.6 6.3 0.66 10.4 1.6 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Fungal_trans PF04082.18 CEH17950.1 - 0.051 12.6 0.0 0.099 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH17950.1 - 0.16 12.1 1.1 0.44 10.7 1.1 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 CEH17952.1 - 3.4e-42 141.6 14.3 3e-11 43.7 1.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH17952.1 - 1.3e-14 54.2 0.8 0.0019 18.5 0.1 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEH17952.1 - 1.6e-05 23.7 1.6 0.23 10.1 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEH17952.1 - 1.8e-05 23.9 0.2 1.6 7.6 0.0 4.6 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CEH17952.1 - 0.00024 20.2 0.7 0.00033 19.7 0.0 1.6 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 CEH17952.1 - 0.00071 18.0 0.0 0.0011 17.3 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 CEH17952.1 - 0.00092 18.1 0.1 1.8 7.2 0.0 3.8 1 1 2 3 3 3 2 Nup133 N terminal like Hira PF07569.11 CEH17952.1 - 0.0031 17.3 0.2 1.8 8.2 0.0 3.3 1 1 1 2 2 2 1 TUP1-like enhancer of split Cytochrom_D1 PF02239.16 CEH17952.1 - 0.073 11.6 0.1 4.4 5.7 0.0 3.1 3 2 2 5 5 5 0 Cytochrome D1 heme domain Pkinase_fungal PF17667.1 CEH17953.1 - 8.7e-15 54.4 5.7 6.6e-11 41.6 0.2 3.6 2 1 1 3 3 3 2 Fungal protein kinase Ribosomal_L37e PF01907.19 CEH17955.1 - 7.2e-27 93.3 13.3 1.4e-26 92.4 13.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 CEH17955.1 - 0.024 14.7 1.6 0.038 14.0 1.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 CEH17955.1 - 0.081 12.9 0.9 0.11 12.5 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2883 PF11097.8 CEH17955.1 - 0.64 10.2 4.9 4.6 7.4 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2883) Ribosomal_L7Ae PF01248.26 CEH17956.1 - 2.5e-22 78.4 0.0 2.9e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FKBP_C PF00254.28 CEH17956.1 - 0.053 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase XRN_M PF17846.1 CEH17957.1 - 1.9e-103 346.8 0.9 4.8e-103 345.5 0.9 1.6 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CEH17957.1 - 3.6e-93 311.5 0.4 8.5e-93 310.2 0.0 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 CEH17957.1 - 2.5e-64 216.6 0.0 4.9e-64 215.6 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 CEH17957.1 - 6.2e-23 80.7 0.8 1.7e-22 79.3 0.8 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 CEH17957.1 - 2.3e-19 69.4 0.1 5.6e-19 68.1 0.1 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain Xrn1_D3 PF18194.1 CEH17957.1 - 0.0025 17.9 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 AAA PF00004.29 CEH17958.1 - 1.6e-41 141.8 0.0 2.7e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CEH17958.1 - 5.1e-11 42.4 0.0 1.2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CEH17958.1 - 2e-08 33.9 0.5 3.8e-08 33.0 0.5 1.4 1 0 0 1 1 1 1 AAA+ lid domain DUF815 PF05673.13 CEH17958.1 - 9.2e-06 25.0 0.0 4.4e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 CEH17958.1 - 9.6e-06 25.8 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CEH17958.1 - 3.2e-05 24.2 1.0 0.031 14.5 0.1 2.6 2 1 1 3 3 2 2 AAA domain AAA_16 PF13191.6 CEH17958.1 - 0.00012 22.5 0.5 0.0053 17.2 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CEH17958.1 - 0.00036 20.5 0.5 0.0033 17.4 0.3 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEH17958.1 - 0.00059 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CEH17958.1 - 0.0027 18.2 0.0 0.011 16.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CEH17958.1 - 0.0052 16.0 0.1 0.085 12.0 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 CEH17958.1 - 0.0055 16.9 0.3 0.015 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.11 CEH17958.1 - 0.0058 16.5 0.1 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 CEH17958.1 - 0.0074 15.9 0.1 0.039 13.6 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_14 PF13173.6 CEH17958.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CEH17958.1 - 0.026 13.9 0.6 0.74 9.1 0.1 2.6 2 1 1 3 3 3 0 KaiC IstB_IS21 PF01695.17 CEH17958.1 - 0.038 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 CEH17958.1 - 0.073 12.2 0.3 0.56 9.4 0.0 2.3 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 CEH17958.1 - 0.075 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 CEH17958.1 - 0.081 13.2 0.6 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CEH17958.1 - 0.089 12.7 0.3 0.79 9.6 0.1 2.2 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.6 CEH17958.1 - 0.11 12.2 0.1 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CEH17958.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 CEH17958.1 - 0.14 11.6 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Histone PF00125.24 CEH17958.1 - 0.15 12.4 0.0 0.15 12.4 0.0 2.2 2 1 1 3 3 2 0 Core histone H2A/H2B/H3/H4 MCM PF00493.23 CEH17959.1 - 8.5e-105 348.8 0.0 1.5e-104 348.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEH17959.1 - 2.8e-34 117.7 0.0 5.4e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEH17959.1 - 5.6e-30 103.6 1.7 1.4e-29 102.4 1.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CEH17959.1 - 1.2e-13 51.5 0.0 2.9e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 CEH17959.1 - 4.1e-06 26.9 0.0 9.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEH17959.1 - 5.8e-06 25.8 0.0 0.0006 19.2 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEH17959.1 - 6.7e-05 22.8 0.1 0.0011 18.8 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEH17959.1 - 0.054 13.2 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 CEH17959.1 - 0.055 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RBD-FIP PF09457.10 CEH17959.1 - 0.057 13.3 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 FIP domain Mg_chelatase_C PF13335.6 CEH17959.1 - 0.14 12.8 5.9 0.071 13.8 1.1 2.9 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA_30 PF13604.6 CEH17959.1 - 0.8 9.4 3.2 0.69 9.6 0.2 2.3 3 0 0 3 3 3 0 AAA domain TRAPP PF04051.16 CEH17961.1 - 4.7e-31 107.5 0.0 1.6e-28 99.3 0.0 2.1 2 0 0 2 2 2 2 Transport protein particle (TRAPP) component SSP160 PF06933.11 CEH17961.1 - 5.7 5.0 11.7 7.6 4.6 11.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NUC173 PF08161.12 CEH17962.1 - 1.4e-58 198.0 0.1 8.2e-57 192.2 0.0 3.4 4 0 0 4 4 4 1 NUC173 domain DNA_pol_phi PF04931.13 CEH17962.1 - 0.036 12.2 3.1 0.3 9.1 4.5 1.8 2 0 0 2 2 2 0 DNA polymerase phi CdiI_2 PF18593.1 CEH17962.1 - 0.12 13.0 0.0 0.45 11.2 0.0 2.0 1 0 0 1 1 1 0 CdiI immunity protein SMC_N PF02463.19 CEH17963.1 - 4.2e-64 216.0 0.0 4.5e-63 212.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CEH17963.1 - 6.7e-20 71.5 1.0 2.4e-19 69.7 0.2 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CEH17963.1 - 4.2e-13 50.2 20.2 4.2e-13 50.2 20.2 5.8 2 2 2 4 4 1 1 AAA domain AAA_21 PF13304.6 CEH17963.1 - 7.6e-11 42.4 5.3 6e-05 23.0 0.8 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CEH17963.1 - 4.9e-06 26.5 7.7 4.9e-06 26.5 7.7 3.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CEH17963.1 - 3.6e-05 23.4 0.1 0.00013 21.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain MscS_porin PF12795.7 CEH17963.1 - 0.00012 21.8 28.8 0.00012 21.8 28.8 6.5 3 2 2 6 6 6 1 Mechanosensitive ion channel porin domain GAS PF13851.6 CEH17963.1 - 0.0055 16.1 13.5 0.0055 16.1 13.5 7.2 3 2 4 7 7 7 4 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 CEH17963.1 - 0.095 13.2 0.1 0.095 13.2 0.1 5.4 2 2 1 3 3 2 0 ABC transporter AAA PF00004.29 CEH17963.1 - 0.17 12.3 3.4 6.3 7.2 0.6 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4140 PF13600.6 CEH17963.1 - 1 9.9 0.0 1 9.9 0.0 9.5 5 3 2 7 7 6 0 N-terminal domain of unknown function (DUF4140) YvbH_ext PF11724.8 CEH17963.1 - 1.3 9.4 4.0 30 5.0 0.1 3.4 3 0 0 3 3 3 0 YvbH-like oligomerisation region Fez1 PF06818.15 CEH17963.1 - 3.1 8.2 84.4 0.4 11.1 19.8 6.1 3 2 3 6 6 6 0 Fez1 DASH_Dad4 PF08650.10 CEH17963.1 - 3.2 7.8 7.3 3.3 7.7 0.2 4.3 4 0 0 4 4 4 0 DASH complex subunit Dad4 NPV_P10 PF05531.12 CEH17963.1 - 4.5 7.8 36.7 4.2 7.9 0.9 8.4 5 4 2 7 7 7 0 Nucleopolyhedrovirus P10 protein Methyltransf_24 PF13578.6 CEH17965.1 - 0.027 15.5 0.2 0.046 14.7 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C65 PF10275.9 CEH17965.1 - 0.028 13.9 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain Peptidase_C101 PF16218.5 CEH17965.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C101 OTU PF02338.19 CEH17965.1 - 0.19 12.3 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 OTU-like cysteine protease BRF1 PF07741.13 CEH17966.1 - 0.035 14.4 3.9 0.088 13.2 3.9 1.7 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF572 PF04502.13 CEH17966.1 - 0.15 11.7 7.8 0.2 11.3 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FSA_C PF10479.9 CEH17966.1 - 1.2 7.2 21.2 1.7 6.7 21.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Plasmodium_Vir PF05795.11 CEH17966.1 - 3.6 6.9 4.9 4.9 6.5 4.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein IBN_N PF03810.19 CEH17968.1 - 0.0065 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain OTU PF02338.19 CEH17968.1 - 0.0085 16.6 0.0 0.0097 16.4 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease PAH PF02671.21 CEH17968.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Paired amphipathic helix repeat CW_binding_2 PF04122.12 CEH17968.1 - 0.13 12.9 0.0 0.17 12.6 0.0 1.4 1 1 0 1 1 1 0 Putative cell wall binding repeat 2 Mitofilin PF09731.9 CEH17970.1 - 0.014 14.3 15.5 0.02 13.7 15.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AAA_13 PF13166.6 CEH17970.1 - 5.4 5.5 12.3 8 5.0 12.3 1.1 1 0 0 1 1 1 0 AAA domain RT_RNaseH_2 PF17919.1 CEH17972.1 - 1.4e-16 60.3 0.0 3.4e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEH17972.1 - 5.9e-15 55.4 0.0 1.4e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEH17972.1 - 1.5e-14 54.2 0.0 5.4e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CEH17972.1 - 3e-05 23.6 0.0 5.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 CEH17973.1 - 0.015 15.2 0.2 0.046 13.7 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 CEH17973.1 - 0.066 12.9 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEH17973.1 - 0.75 10.0 5.2 1.3 9.2 5.2 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.14 CEH17974.1 - 3.4e-32 112.0 0.0 2.5e-25 89.5 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEH17975.1 - 2.2e-22 79.5 0.0 1.1e-21 77.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 CEH17975.1 - 5.3e-15 55.3 0.0 8.6e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CEH17975.1 - 3.5e-07 30.0 0.0 8.8e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CEH17975.1 - 0.00015 21.5 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain eIF3g PF12353.8 CEH17975.1 - 0.057 13.8 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF1180 PF06679.12 CEH17975.1 - 3.2 8.1 5.0 6.7 7.1 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4149 PF13664.6 CEH17976.1 - 0.059 13.7 8.7 1 9.7 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) PRRSV_2b PF07069.11 CEH17976.1 - 0.67 10.5 3.8 7.2 7.2 0.3 2.8 1 1 1 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Oxidored-like PF09791.9 CEH17980.1 - 1.2e-07 31.3 5.4 1.2e-07 31.3 5.4 1.6 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal WD40 PF00400.32 CEH17981.1 - 2.5e-06 28.1 0.9 0.01 16.7 0.0 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH17981.1 - 0.00084 19.6 0.0 0.21 11.9 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DNApol3-delta_C PF09115.10 CEH17981.1 - 0.059 13.9 0.3 0.12 12.9 0.3 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal RPW8 PF05659.11 CEH17981.1 - 0.086 12.5 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Y_phosphatase PF00102.27 CEH17982.1 - 1.4e-25 90.2 2.1 3.6e-16 59.4 0.0 3.1 2 1 1 3 3 3 3 Protein-tyrosine phosphatase SNCAIP_SNCA_bd PF16700.5 CEH17982.1 - 0.17 11.6 0.1 0.43 10.3 0.1 1.7 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain MFS_1 PF07690.16 CEH17983.1 - 5.7e-33 114.3 76.5 3.8e-31 108.3 48.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Aconitase PF00330.20 CEH17984.1 - 1.1e-161 538.9 0.0 1.6e-161 538.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEH17984.1 - 4e-33 114.5 0.0 7.4e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain VirE1 PF12189.8 CEH17984.1 - 0.071 13.2 0.4 0.071 13.2 0.4 1.9 2 0 0 2 2 2 0 Single-strand DNA-binding protein CEP19 PF14933.6 CEH17984.1 - 0.19 12.0 0.3 6.6 7.0 0.1 2.8 3 0 0 3 3 3 0 CEP19-like protein DUF4885 PF16226.5 CEH17984.1 - 0.27 10.2 0.7 2 7.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4885) UQ_con PF00179.26 CEH17986.1 - 3.6e-14 52.6 0.0 4.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.18 CEH17986.1 - 0.059 12.7 1.4 0.11 11.8 0.1 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PLRV_ORF5 PF01690.17 CEH17987.1 - 0.014 14.2 0.5 0.016 14.0 0.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein ETF PF01012.21 CEH17989.1 - 3.8e-41 141.0 3.0 4.8e-41 140.6 3.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain EF-hand_6 PF13405.6 CEH17991.1 - 3.2e-07 29.7 0.0 0.026 14.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CEH17991.1 - 6.4e-07 29.7 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CEH17991.1 - 1.5e-06 27.4 0.0 0.023 14.2 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 CEH17991.1 - 2.1e-05 23.7 0.0 0.057 13.0 0.0 2.4 2 0 0 2 2 2 2 EF hand RRM_1 PF00076.22 CEH17991.1 - 4.2e-05 23.3 0.1 0.00014 21.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_8 PF13833.6 CEH17991.1 - 0.0052 16.6 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair Peptidase_M1 PF01433.20 CEH17992.1 - 7.2e-68 228.4 0.0 1.2e-67 227.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CEH17992.1 - 2.3e-42 145.3 0.2 1.2e-41 143.0 0.2 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CEH17992.1 - 2.1e-38 132.7 4.9 2.2e-19 70.1 0.5 2.6 1 1 1 2 2 2 2 ERAP1-like C-terminal domain Gcd10p PF04189.13 CEH17993.1 - 9.2e-54 182.6 0.0 1.5e-53 181.9 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family DUF202 PF02656.15 CEH17994.1 - 2.4e-20 72.8 4.1 3.5e-20 72.2 0.6 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF5336 PF17270.2 CEH17994.1 - 0.009 15.7 0.6 0.15 11.7 0.1 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5336) DUF3784 PF12650.7 CEH17994.1 - 0.025 14.7 1.6 0.07 13.3 1.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) FCD PF07729.12 CEH17994.1 - 0.039 14.4 0.1 0.071 13.5 0.1 1.5 1 1 0 1 1 1 0 FCD domain FA_hydroxylase PF04116.13 CEH17995.1 - 5.6e-19 68.8 17.8 5.6e-19 68.8 17.8 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4670 PF15709.5 CEH17995.1 - 0.28 10.5 1.4 0.36 10.1 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) TIP41 PF04176.13 CEH17996.1 - 4.2e-25 88.2 0.0 1.8e-24 86.1 0.0 2.0 2 1 0 2 2 2 1 TIP41-like family Pex14_N PF04695.13 CEH17997.1 - 1.9e-26 93.6 0.7 1.9e-26 93.6 0.7 2.3 3 0 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1664 PF07889.12 CEH17997.1 - 8.6e-05 22.6 0.5 0.00019 21.5 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Atg14 PF10186.9 CEH17997.1 - 0.0013 17.9 0.1 0.0019 17.4 0.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_I PF06008.14 CEH17997.1 - 0.0028 17.4 3.9 0.0047 16.7 3.9 1.2 1 0 0 1 1 1 1 Laminin Domain I DUF5344 PF17279.2 CEH17997.1 - 0.0077 16.8 5.5 0.083 13.5 1.7 2.5 1 1 1 2 2 2 1 Family of unknown function (DUF5344) Myosin_tail_1 PF01576.19 CEH17997.1 - 0.011 13.6 4.7 0.015 13.2 4.7 1.0 1 0 0 1 1 1 0 Myosin tail Sec34 PF04136.15 CEH17997.1 - 0.021 14.7 2.6 0.85 9.5 0.1 2.3 2 0 0 2 2 2 0 Sec34-like family zf-C4H2 PF10146.9 CEH17997.1 - 0.026 14.8 0.1 0.06 13.7 0.0 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein DUF2524 PF10732.9 CEH17997.1 - 0.037 14.3 0.4 0.068 13.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) AAA_13 PF13166.6 CEH17997.1 - 0.056 12.1 0.7 0.073 11.7 0.7 1.1 1 0 0 1 1 1 0 AAA domain Ran-binding PF05508.11 CEH17997.1 - 0.059 12.3 2.9 0.099 11.6 2.9 1.3 1 0 0 1 1 1 0 RanGTP-binding protein NPV_P10 PF05531.12 CEH17997.1 - 0.066 13.7 7.4 5.4 7.6 3.3 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 CEH17997.1 - 0.11 11.9 3.7 0.18 11.2 3.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tektin PF03148.14 CEH17997.1 - 0.12 11.2 4.3 3.1 6.4 0.1 2.1 1 1 1 2 2 2 0 Tektin family Matrilin_ccoil PF10393.9 CEH17997.1 - 0.12 12.2 0.2 0.36 10.7 0.2 1.8 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin IFT57 PF10498.9 CEH17997.1 - 0.15 11.0 5.7 0.4 9.6 1.9 2.1 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 EzrA PF06160.12 CEH17997.1 - 0.17 10.0 4.7 0.26 9.4 4.7 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Cortex-I_coil PF09304.10 CEH17997.1 - 0.18 12.1 6.4 0.15 12.3 4.2 1.8 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF948 PF06103.11 CEH17997.1 - 0.22 11.8 4.4 3.4 8.0 0.8 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3584 PF12128.8 CEH17997.1 - 0.22 9.0 5.1 0.31 8.5 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.19 CEH17997.1 - 0.33 10.7 7.1 0.95 9.2 7.1 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family SKA1 PF07160.12 CEH17997.1 - 0.48 10.2 3.8 4.5 7.1 3.7 2.1 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 TMPIT PF07851.13 CEH17997.1 - 0.54 9.4 2.3 0.97 8.6 2.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 CEH17997.1 - 0.63 8.9 8.4 3.7 6.3 0.9 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.11 CEH17997.1 - 0.78 9.8 8.1 2.3 8.3 3.2 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RmuC PF02646.16 CEH17997.1 - 0.8 8.8 5.5 7.3 5.6 0.6 2.2 1 1 1 2 2 2 0 RmuC family Laminin_II PF06009.12 CEH17997.1 - 1 9.4 6.2 2.6 8.0 6.0 1.8 1 1 0 1 1 1 0 Laminin Domain II TPR_MLP1_2 PF07926.12 CEH17997.1 - 1.1 9.3 8.1 0.36 10.9 0.8 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Occludin_ELL PF07303.13 CEH17997.1 - 1.1 10.0 4.1 21 5.9 4.1 2.2 1 1 0 1 1 1 0 Occludin homology domain BLOC1_2 PF10046.9 CEH17997.1 - 1.3 9.4 5.9 2.5 8.5 0.6 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1319 PF07028.11 CEH17997.1 - 2.1 8.6 7.8 27 5.0 5.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) DUF812 PF05667.11 CEH17997.1 - 3.5 6.4 10.1 75 2.0 10.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Mt_ATP-synt_D PF05873.12 CEH17997.1 - 4 7.3 5.5 14 5.5 0.4 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) GATase_4 PF13230.6 CEH17998.1 - 1.2e-18 66.9 0.1 4.4e-18 65.2 0.1 1.7 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 CEH17998.1 - 5.6e-10 39.5 0.0 1.2e-09 38.5 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF4203 PF13886.6 CEH17999.1 - 9.9e-06 25.4 13.4 9.9e-06 25.4 13.4 2.0 1 1 0 2 2 2 2 Domain of unknown function (DUF4203) PX PF00787.24 CEH18000.1 - 1.3e-17 63.8 0.0 2.9e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 PX domain BshC PF10079.9 CEH18000.1 - 0.16 10.7 0.1 0.24 10.1 0.1 1.3 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC ORC_WH_C PF18137.1 CEH18001.1 - 3.8e-37 127.5 0.0 7.6e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 CEH18001.1 - 0.00023 20.4 0.1 0.004 16.3 0.0 2.5 3 0 0 3 3 3 1 Origin recognition complex (ORC) subunit 3 N-terminus PRK PF00485.18 CEH18005.1 - 2.9e-07 30.4 0.0 3.8e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 CEH18005.1 - 0.00025 20.1 0.0 0.00041 19.4 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 CEH18005.1 - 0.0027 16.9 0.0 0.0038 16.4 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 CEH18005.1 - 0.0029 17.7 0.4 0.3 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEH18005.1 - 0.0033 18.0 0.0 0.02 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEH18005.1 - 0.0063 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CEH18005.1 - 0.0093 16.4 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CEH18005.1 - 0.014 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 CEH18005.1 - 0.054 12.6 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.12 CEH18005.1 - 0.082 12.7 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DDE_3 PF13358.6 CEH18006.1 - 5.3e-15 55.5 0.0 7.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease FBA_3 PF08268.12 CEH18007.1 - 0.0016 18.4 0.4 0.0026 17.7 0.4 1.3 1 0 0 1 1 1 1 F-box associated domain RT_RNaseH_2 PF17919.1 CEH18008.1 - 1.2e-19 70.2 0.0 2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEH18008.1 - 7.2e-16 58.4 0.0 1.6e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEH18008.1 - 1.1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEH18009.1 - 1.8e-11 44.3 0.0 4.8e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 CEH18009.1 - 0.0098 16.0 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_3 PF13358.6 CEH18009.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease rve_3 PF13683.6 CEH18009.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Tim54 PF11711.8 CEH18010.1 - 4.4e-47 160.7 0.0 8.4e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF3331 PF11811.8 CEH18010.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) SPX PF03105.19 CEH18011.1 - 4.5 7.1 8.7 6.5 6.6 8.7 1.3 1 0 0 1 1 1 0 SPX domain Mito_carr PF00153.27 CEH18012.1 - 3.9e-38 129.3 3.4 9.1e-18 64.0 0.1 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein NCE101 PF11654.8 CEH18013.1 - 1.3e-17 63.2 0.2 1.9e-17 62.7 0.2 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 Surp PF01805.20 CEH18015.1 - 3.6e-05 23.7 0.0 7.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 CEH18015.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 CEH18015.1 - 0.16 12.8 0.0 0.45 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Rad60-SLD PF11976.8 CEH18016.1 - 3.8e-06 26.6 0.0 9.8e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TmoB PF06234.12 CEH18016.1 - 0.07 13.2 0.3 0.48 10.5 0.0 2.5 3 0 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) DUF2151 PF10221.9 CEH18016.1 - 1.1 7.8 6.3 0.86 8.1 4.4 1.7 1 1 1 2 2 2 0 Cell cycle and development regulator BRO1 PF03097.18 CEH18017.1 - 8.7e-96 321.1 1.2 1.3e-95 320.5 0.0 1.9 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CEH18017.1 - 3.5e-36 125.0 15.9 7.1e-34 117.4 15.9 2.3 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF5315 PF17242.2 CEH18017.1 - 0.17 11.8 5.3 1.4 8.8 0.9 3.1 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) FliT PF05400.13 CEH18017.1 - 7.3 7.5 12.5 0.19 12.5 3.0 3.3 3 1 0 3 3 3 0 Flagellar protein FliT MMM1 PF10296.9 CEH18018.1 - 2.7e-53 181.2 0.0 1.3e-52 178.9 0.0 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Cupin_1 PF00190.22 CEH18019.1 - 1.6e-30 105.7 0.0 5.6e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CEH18019.1 - 1.5e-27 95.1 0.9 3.9e-14 52.1 0.3 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 CEH18019.1 - 3.9e-08 32.9 0.0 0.012 15.2 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 CEH18019.1 - 4.4e-07 29.9 0.3 0.0011 18.9 0.0 2.6 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_7 PF12973.7 CEH18019.1 - 8e-05 22.5 0.1 0.26 11.2 0.0 2.7 2 0 0 2 2 2 2 ChrR Cupin-like domain DUF1971 PF09313.11 CEH18019.1 - 0.011 15.8 0.1 0.029 14.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) cNMP_binding PF00027.29 CEH18019.1 - 0.011 15.8 0.0 0.5 10.5 0.0 2.4 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain MitoNEET_N PF10660.9 CEH18019.1 - 0.021 14.9 0.0 0.072 13.1 0.0 1.9 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Ectoine_synth PF06339.12 CEH18019.1 - 0.058 13.6 0.0 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Ectoine synthase Cupin_6 PF12852.7 CEH18019.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Cupin HSF_DNA-bind PF00447.17 CEH18020.1 - 3.1e-30 104.7 0.4 4.7e-30 104.1 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding HisG PF01634.18 CEH18024.1 - 1.9e-52 177.4 0.0 2.6e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 CEH18024.1 - 6.6e-24 83.9 0.0 1.6e-23 82.6 0.1 1.7 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 CEH18024.1 - 0.00015 21.8 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like Zn_clus PF00172.18 CEH18025.1 - 6.8e-09 35.7 7.5 1.1e-08 35.1 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CEH18025.1 - 0.00021 20.4 0.0 0.00042 19.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain OTU PF02338.19 CEH18027.1 - 2.1e-13 50.9 0.0 5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CEH18027.1 - 0.018 14.5 0.0 5.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase C65 Otubain Lin-8 PF03353.15 CEH18027.1 - 4.8 6.7 6.4 2.1 7.9 0.5 2.6 2 1 1 3 3 3 0 Ras-mediated vulval-induction antagonist PhoLip_ATPase_C PF16212.5 CEH18028.1 - 2.2e-49 168.5 15.4 2.2e-49 168.5 15.4 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEH18028.1 - 2.8e-17 62.1 1.3 7e-17 60.9 1.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CEH18028.1 - 3.1e-13 50.5 0.9 2.2e-06 28.1 0.7 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEH18028.1 - 6.3e-10 39.0 0.0 1.9e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CEH18028.1 - 2.5e-08 33.7 5.0 0.002 17.7 0.0 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 CEH18028.1 - 0.016 15.0 0.0 0.041 13.6 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase RINT1_TIP1 PF04437.13 CEH18029.1 - 8e-54 183.3 0.0 4.9e-53 180.8 0.0 2.1 1 1 0 1 1 1 1 RINT-1 / TIP-1 family BLUF PF04940.12 CEH18029.1 - 0.12 12.5 0.0 0.38 10.9 0.0 1.8 1 1 0 1 1 1 0 Sensors of blue-light using FAD TipAS PF07739.13 CEH18029.1 - 7.1 7.2 10.7 0.49 11.0 0.4 3.6 4 0 0 4 4 4 0 TipAS antibiotic-recognition domain RINT1_TIP1 PF04437.13 CEH18030.1 - 3.6e-10 39.3 0.1 4.1e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family C12orf66_like PF09404.10 CEH18030.1 - 0.092 11.6 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like Nop PF01798.18 CEH18031.1 - 1.5e-71 240.5 0.0 2.1e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CEH18031.1 - 3e-38 131.4 4.5 7e-38 130.2 4.5 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain Glycophorin_A PF01102.18 CEH18032.1 - 0.00015 22.0 0.0 0.00036 20.7 0.0 1.7 1 0 0 1 1 1 1 Glycophorin A Syndecan PF01034.20 CEH18032.1 - 0.0039 17.1 0.9 0.0069 16.3 0.9 1.3 1 0 0 1 1 1 1 Syndecan domain Podoplanin PF05808.11 CEH18032.1 - 0.012 15.7 0.1 0.028 14.5 0.0 1.6 2 0 0 2 2 2 0 Podoplanin DUF4381 PF14316.6 CEH18032.1 - 0.029 14.6 0.2 0.049 13.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TRP PF06011.12 CEH18032.1 - 0.03 13.0 0.1 0.046 12.4 0.1 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Amnionless PF14828.6 CEH18032.1 - 0.059 12.2 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless TraL PF07178.11 CEH18032.1 - 0.079 13.4 0.2 0.13 12.8 0.2 1.2 1 0 0 1 1 1 0 TraL protein EphA2_TM PF14575.6 CEH18032.1 - 0.17 12.7 0.0 0.3 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CCSMST1 PF15013.6 CEH18032.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 CCSMST1 family VSP PF03302.13 CEH18032.1 - 0.18 10.6 0.5 0.31 9.9 0.5 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein VEGFR-2_TMD PF17988.1 CEH18032.1 - 0.39 10.2 6.7 0.64 9.5 6.7 1.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain FeoB_associated PF12669.7 CEH18032.1 - 3.6 8.1 4.2 11 6.6 4.2 1.8 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein WD40 PF00400.32 CEH18033.1 - 0.0069 17.2 0.0 0.17 12.8 0.0 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH18033.1 - 0.13 12.5 0.0 13 6.2 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain FAD_binding_3 PF01494.19 CEH18034.1 - 2.3e-21 76.4 5.0 4.2e-11 42.7 0.4 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 CEH18034.1 - 9.7e-05 22.1 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CEH18034.1 - 0.00031 19.9 1.7 0.25 10.3 0.0 3.2 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 CEH18034.1 - 0.00083 19.4 0.1 0.0071 16.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.10 CEH18034.1 - 0.0016 17.6 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 CEH18034.1 - 0.023 14.9 0.0 0.075 13.3 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.17 CEH18034.1 - 0.067 13.8 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 CEH18034.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox_2 PF07992.14 CEH18034.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEH18034.1 - 0.14 12.8 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 CEH18034.1 - 0.16 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 CEH18034.1 - 0.22 10.8 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Chitin_synth_1 PF01644.17 CEH18035.1 - 3.5e-79 264.5 0.1 4.9e-79 264.0 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CEH18035.1 - 1.8e-30 104.7 0.3 4.9e-30 103.3 0.2 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CEH18035.1 - 3.4e-24 85.4 11.1 9.6e-21 74.0 0.7 2.1 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CEH18035.1 - 1e-05 25.5 8.7 4.6e-05 23.4 8.7 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DUF1218 PF06749.12 CEH18035.1 - 9.9 6.8 7.2 2 9.0 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Polysacc_deac_1 PF01522.21 CEH18036.1 - 2.5e-26 92.0 0.0 1e-25 90.0 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEH18036.1 - 0.0075 15.5 0.0 0.0097 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 CEH18036.1 - 0.068 12.8 0.3 0.13 11.9 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Roughex PF06020.11 CEH18037.1 - 0.34 10.0 6.6 0.54 9.3 6.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF5327 PF17261.2 CEH18037.1 - 4.8 8.0 7.1 79 4.1 3.8 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5327) CCDC53 PF10152.9 CEH18037.1 - 8.1 6.8 10.3 1.2 9.6 3.1 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TBP PF00352.21 CEH18038.1 - 1.5e-67 223.5 0.1 9.8e-33 112.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CEH18038.1 - 1.5e-05 25.0 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 CEH18038.1 - 0.11 12.3 0.1 0.6 10.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) PIP5K PF01504.18 CEH18039.1 - 6.2e-42 143.7 0.0 1.7e-32 112.8 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CEH18039.1 - 9.9e-20 70.6 0.0 1.5e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tfb5 PF06331.12 CEH18040.1 - 1.1e-24 86.1 0.2 1.2e-24 86.0 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Tim17 PF02466.19 CEH18041.1 - 9.8e-32 109.6 7.0 1.2e-31 109.3 7.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family VIT1 PF01988.19 CEH18041.1 - 0.062 13.2 2.2 0.081 12.8 1.8 1.7 1 1 0 1 1 1 0 VIT family EMC1_C PF07774.13 CEH18042.1 - 4e-56 190.0 0.0 6.5e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CEH18042.1 - 7.2e-08 32.3 13.1 0.00037 20.2 2.6 4.9 3 2 2 5 5 5 3 PQQ-like domain PQQ PF01011.21 CEH18042.1 - 0.063 13.2 4.5 39 4.4 0.1 5.2 5 0 0 5 5 5 0 PQQ enzyme repeat DUF1668 PF07893.13 CEH18042.1 - 0.098 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) COesterase PF00135.28 CEH18045.1 - 6.2e-68 229.9 0.0 1.1e-67 229.1 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CEH18045.1 - 2.6e-06 27.4 0.0 0.0012 18.8 0.0 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold NMT1 PF09084.11 CEH18045.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 2 0 0 2 2 2 0 NMT1/THI5 like P53 PF00870.18 CEH18046.1 - 0.094 12.5 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 P53 DNA-binding domain Pkinase PF00069.25 CEH18047.1 - 3.3e-72 243.0 0.0 4.1e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH18047.1 - 1e-31 110.2 0.0 1.4e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEH18047.1 - 9e-13 48.7 0.8 2.6e-12 47.3 0.8 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CEH18047.1 - 1.3e-06 27.6 0.0 2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CEH18047.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.5 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 CEH18047.1 - 0.11 12.1 0.0 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEH18047.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C2 PF00168.30 CEH18047.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.8 1 1 0 1 1 1 0 C2 domain GST_N_3 PF13417.6 CEH18048.1 - 9.1e-19 67.7 0.0 3.1e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEH18048.1 - 1.7e-16 60.2 0.1 3.7e-15 56.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEH18048.1 - 7.5e-12 45.4 0.1 2.8e-11 43.6 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 CEH18048.1 - 2.3e-05 24.9 0.0 3.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEH18048.1 - 0.0017 18.4 0.5 0.0064 16.5 0.4 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CEH18048.1 - 0.0075 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Acyl_transf_3 PF01757.22 CEH18049.1 - 3e-05 23.2 6.0 3e-05 23.2 6.0 2.5 1 1 0 2 2 2 2 Acyltransferase family Glyco_tranf_2_3 PF13641.6 CEH18050.1 - 6.2e-11 42.6 0.4 3e-05 24.0 0.1 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEH18050.1 - 1.6e-08 34.7 7.5 1.6e-08 34.7 7.5 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Histone PF00125.24 CEH18051.1 - 8e-17 61.8 0.0 1.1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CEH18051.1 - 2.3e-12 46.4 0.1 4.8e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CEH18051.1 - 0.00083 19.6 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ_CXXCXGXG PF00684.19 CEH18052.1 - 0.88 10.0 25.1 0.99 9.8 13.1 2.4 1 1 0 2 2 2 0 DnaJ central domain Acyl_transf_3 PF01757.22 CEH18054.1 - 1.4e-17 63.8 29.7 3.2e-17 62.6 29.7 1.6 1 0 0 1 1 1 1 Acyltransferase family Glyco_transf_20 PF00982.21 CEH18055.1 - 1.6e-153 511.8 0.0 2.2e-153 511.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEH18055.1 - 3.2e-24 85.4 0.0 5.9e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 CEH18055.1 - 0.019 14.7 0.0 0.07 12.9 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF89 PF01937.19 CEH18056.1 - 2.8e-107 358.7 0.5 3.6e-107 358.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 WD40 PF00400.32 CEH18056.1 - 0.015 16.1 0.0 3.2 8.8 0.0 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat Colicin_Ia PF11504.8 CEH18057.1 - 0.069 13.3 0.0 0.081 13.0 0.0 1.1 1 0 0 1 1 1 0 Colicin Ia Cation_efflux PF01545.21 CEH18058.1 - 1.6e-06 28.0 5.6 2.9e-06 27.2 5.6 1.5 1 0 0 1 1 1 1 Cation efflux family DUF2162 PF09930.9 CEH18058.1 - 1.1 8.7 5.5 3.6 6.9 5.5 1.8 1 1 0 1 1 1 0 Predicted transporter (DUF2162) E1_dh PF00676.20 CEH18059.1 - 4e-64 216.4 0.0 5.6e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CEH18059.1 - 2.1e-63 213.2 0.0 3.5e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CEH18059.1 - 8e-47 158.7 0.0 1.4e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CEH18059.1 - 1e-14 53.8 1.5 1.2e-14 53.6 0.3 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus HEPN_SAV_6107 PF18726.1 CEH18060.1 - 0.14 12.7 0.0 0.17 12.4 0.0 1.1 1 0 0 1 1 1 0 SAV_6107-like HEPN Myb_DNA-binding PF00249.31 CEH18062.1 - 6.6e-16 58.2 0.0 1.2e-07 31.8 0.0 3.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEH18062.1 - 4.8e-13 49.1 0.0 9e-06 25.9 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF5364 PF17322.2 CEH18062.1 - 0.081 13.2 2.5 0.098 13.0 0.0 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5364) DUF1749 PF08538.10 CEH18066.1 - 5.9e-49 166.8 0.0 1.5e-47 162.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) DUF5572 PF17733.1 CEH18066.1 - 3.8e-18 65.0 1.3 7e-18 64.2 1.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Abhydrolase_6 PF12697.7 CEH18066.1 - 3.4e-06 27.8 0.0 4.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH18066.1 - 1.1e-05 24.8 0.0 5.1e-05 22.7 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH18066.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CEH18066.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase EF-hand_1 PF00036.32 CEH18068.1 - 1.5e-27 93.1 9.6 3.3e-08 32.5 0.0 5.3 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CEH18068.1 - 5.8e-25 87.5 7.7 3.4e-17 62.7 1.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEH18068.1 - 2.2e-23 80.1 5.3 2.8e-06 26.8 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CEH18068.1 - 2.9e-13 48.6 11.0 0.00043 19.7 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 CEH18068.1 - 3.8e-13 49.0 10.2 0.00011 22.0 1.6 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 CEH18068.1 - 3.7e-08 33.2 3.7 0.0067 16.4 0.0 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEH18068.1 - 0.0011 19.2 0.8 0.13 12.6 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CEH18068.1 - 0.0034 17.7 1.4 1.6 9.0 0.1 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_3 PF09069.11 CEH18068.1 - 0.046 14.1 0.1 0.16 12.4 0.0 1.8 2 1 0 2 2 2 0 EF-hand Caleosin PF05042.13 CEH18068.1 - 0.41 10.6 3.5 13 5.7 0.1 3.1 2 1 1 3 3 3 0 Caleosin related protein CBF_beta PF02312.17 CEH18071.1 - 0.023 14.3 0.2 0.065 12.9 0.2 1.7 1 1 0 1 1 1 0 Core binding factor beta subunit Synaptobrevin PF00957.21 CEH18072.1 - 1.5e-32 111.2 1.3 1.7e-32 111.1 1.3 1.0 1 0 0 1 1 1 1 Synaptobrevin CK_II_beta PF01214.18 CEH18073.1 - 1.2e-81 272.8 0.0 1.6e-81 272.5 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CSTF2_hinge PF14327.6 CEH18074.1 - 1.6e-31 108.6 1.9 3e-31 107.7 1.9 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 CEH18074.1 - 1.8e-20 72.5 0.0 2.8e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 CEH18074.1 - 4.2e-12 45.4 9.0 5.4e-12 45.1 4.3 2.7 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 CEH18074.1 - 0.005 16.9 0.1 0.011 15.8 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif DUF2249 PF10006.9 CEH18074.1 - 0.029 14.2 0.0 0.69 9.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) MRP-L27 PF09809.9 CEH18075.1 - 0.00027 20.7 0.3 0.0051 16.6 0.3 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF3535 PF12054.8 CEH18076.1 - 3.7e-96 323.0 5.6 7.3e-95 318.8 0.1 3.6 4 1 0 4 4 4 2 Domain of unknown function (DUF3535) SNF2_N PF00176.23 CEH18076.1 - 5.7e-64 216.0 0.0 1.3e-63 214.9 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEH18076.1 - 1.9e-16 60.4 0.0 5.3e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 CEH18076.1 - 1.4e-12 46.7 26.4 0.71 10.3 0.2 11.3 10 0 0 10 10 10 6 HEAT repeat Vac14_Fab1_bd PF12755.7 CEH18076.1 - 2.2e-09 37.8 0.0 0.0085 16.7 0.0 3.3 2 1 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 CEH18076.1 - 0.0001 22.6 28.4 0.24 11.8 0.4 8.4 8 0 0 8 8 8 2 HEAT repeats DUF3385 PF11865.8 CEH18076.1 - 0.03 14.3 0.4 0.39 10.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) ResIII PF04851.15 CEH18076.1 - 0.039 13.9 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Adaptin_N PF01602.20 CEH18076.1 - 0.18 10.3 2.9 3.2 6.2 0.2 2.9 4 0 0 4 4 4 0 Adaptin N terminal region Cnd1 PF12717.7 CEH18076.1 - 0.31 11.1 7.8 0.93 9.5 0.8 3.8 3 2 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.8 CEH18076.1 - 0.43 11.2 5.9 31 5.2 0.0 5.2 6 0 0 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.6 CEH18076.1 - 1.1 9.9 29.3 5 7.7 0.9 9.9 9 2 2 11 11 10 0 HEAT-like repeat Formyl_trans_N PF00551.19 CEH18077.1 - 9.1e-35 120.0 0.0 1e-32 113.3 0.0 2.6 1 1 0 1 1 1 1 Formyl transferase NuA4 PF09340.10 CEH18078.1 - 3.8e-17 61.9 0.1 6.6e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 EB PF01683.18 CEH18079.1 - 0.25 11.7 7.0 1.4 9.3 0.2 2.3 2 0 0 2 2 2 0 EB module Plant_zn_clust PF10533.9 CEH18079.1 - 0.3 11.1 5.3 0.34 10.9 2.5 2.4 2 0 0 2 2 2 0 Plant zinc cluster domain hEGF PF12661.7 CEH18079.1 - 1.1 10.0 0.2 1.1 10.0 0.2 2.5 2 0 0 2 2 2 0 Human growth factor-like EGF SUZ PF12752.7 CEH18080.1 - 4.7e-11 43.3 0.9 4.7e-11 43.3 0.9 4.1 3 1 0 3 3 3 1 SUZ domain Serglycin PF04360.12 CEH18080.1 - 0.059 13.3 1.4 0.32 10.9 0.0 2.6 3 0 0 3 3 3 0 Serglycin Aa_trans PF01490.18 CEH18081.1 - 4.4e-68 229.9 17.3 6.4e-68 229.3 17.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NOT2_3_5 PF04153.18 CEH18082.1 - 9.9e-32 109.8 0.3 9.9e-32 109.8 0.3 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Protocadherin PF08374.11 CEH18083.1 - 0.0003 20.9 0.2 0.00045 20.3 0.2 1.3 1 0 0 1 1 1 1 Protocadherin LapA_dom PF06305.11 CEH18083.1 - 0.0031 17.3 0.5 0.0053 16.5 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Vpu PF00558.19 CEH18083.1 - 0.0081 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Vpu protein MFS_1 PF07690.16 CEH18083.1 - 0.032 13.2 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Imm17 PF15562.6 CEH18083.1 - 0.13 12.1 0.3 0.23 11.3 0.3 1.4 1 0 0 1 1 1 0 Immunity protein 17 Sec1 PF00995.23 CEH18084.1 - 3.3e-118 396.4 0.0 4e-118 396.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Dioxygenase_C PF00775.21 CEH18085.1 - 0.00012 21.6 0.7 0.00017 21.1 0.1 1.5 2 0 0 2 2 2 1 Dioxygenase CDH-cyt PF16010.5 CEH18086.1 - 3.2e-16 59.6 1.5 1.9e-15 57.0 2.4 1.8 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase DUF4079 PF13301.6 CEH18086.1 - 3.3e-08 33.8 0.1 1.1e-05 25.6 0.1 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF4079) Cytochrom_B561 PF03188.16 CEH18086.1 - 4.5e-08 33.3 10.9 1e-07 32.2 10.9 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 CEH18086.1 - 0.00012 21.9 3.6 0.00012 21.9 3.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.17 CEH18086.1 - 0.00061 20.0 0.1 0.0011 19.1 0.1 1.3 1 0 0 1 1 1 1 DOMON domain Cation_efflux PF01545.21 CEH18086.1 - 0.18 11.5 6.0 0.11 12.2 1.3 2.2 1 1 1 2 2 2 0 Cation efflux family MerC PF03203.14 CEH18086.1 - 0.51 10.8 14.1 1.3 9.5 8.6 3.0 3 1 0 3 3 3 0 MerC mercury resistance protein L_HMGIC_fpl PF10242.9 CEH18086.1 - 1.1 9.4 6.9 1.8 8.7 0.2 2.4 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein ATPase_gene1 PF09527.10 CEH18086.1 - 4.7 7.5 13.2 0.21 11.8 6.0 2.4 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DSPc PF00782.20 CEH18087.1 - 1.5e-21 76.6 0.0 2.3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEH18087.1 - 0.00087 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 CEH18087.1 - 0.015 14.2 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Init_tRNA_PT PF04179.12 CEH18087.1 - 0.063 13.6 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 CEH18087.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate SRP19 PF01922.17 CEH18087.1 - 0.15 13.1 0.0 0.48 11.4 0.0 1.8 2 0 0 2 2 2 0 SRP19 protein Ribophorin_II PF05817.14 CEH18087.1 - 0.16 10.5 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II ABM PF03992.16 CEH18088.1 - 1.6e-06 28.1 0.0 1.8e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ADH_zinc_N PF00107.26 CEH18089.1 - 1e-12 48.1 0.1 1.7e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEH18089.1 - 0.00041 21.4 0.0 0.0016 19.5 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH18089.1 - 0.0037 17.1 0.0 1.3 8.9 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 CEH18089.1 - 0.051 14.0 0.2 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 CEH18089.1 - 0.06 12.8 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family VIT1 PF01988.19 CEH18090.1 - 1.5e-61 208.0 3.1 2.1e-61 207.5 3.1 1.2 1 0 0 1 1 1 1 VIT family Lactonase PF10282.9 CEH18091.1 - 2.7e-22 79.5 0.0 6e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller EthD PF07110.11 CEH18092.1 - 3.9e-06 27.9 0.5 0.015 16.4 0.1 2.5 2 0 0 2 2 2 2 EthD domain ESPR PF13018.6 CEH18092.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system Mvb12 PF09452.10 CEH18092.1 - 0.12 12.9 0.3 21 5.6 0.0 2.9 3 0 0 3 3 3 0 ESCRT-I subunit Mvb12 DUF5376 PF17346.2 CEH18093.1 - 0.19 12.1 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5376) Surp PF01805.20 CEH18094.1 - 1.7e-51 172.0 8.8 1.1e-18 66.9 0.3 3.6 2 1 1 3 3 3 3 Surp module MutS_V PF00488.21 CEH18094.1 - 1.4e-46 158.9 0.1 2.4e-46 158.2 0.1 1.3 1 0 0 1 1 1 1 MutS domain V PRP21_like_P PF12230.8 CEH18094.1 - 4.5e-41 141.1 0.3 1.2e-40 139.8 0.3 1.7 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein MutS_III PF05192.18 CEH18094.1 - 2.1e-09 37.9 0.9 2.1e-09 37.9 0.9 2.4 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 CEH18094.1 - 0.069 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV zf_UBZ PF18439.1 CEH18094.1 - 0.096 12.3 0.2 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Toprim_Crpt PF13342.6 CEH18094.1 - 0.1 12.6 9.5 7.8 6.5 0.4 3.5 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase CTI PF06934.11 CEH18094.1 - 0.13 10.8 0.1 0.2 10.1 0.1 1.2 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) Tox-GHH PF15636.6 CEH18094.1 - 4.4 7.4 11.7 0.052 13.5 3.1 2.2 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin UQ_con PF00179.26 CEH18095.1 - 4.3e-45 152.8 0.0 5e-45 152.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEH18095.1 - 0.043 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B SLD3 PF08639.10 CEH18096.1 - 6.8e-09 35.0 1.9 6.8e-09 35.0 1.9 1.8 2 0 0 2 2 2 1 DNA replication regulator SLD3 SMC_N PF02463.19 CEH18097.1 - 6.7e-21 74.7 0.0 1.2e-20 73.9 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CEH18097.1 - 2.3e-15 57.7 13.9 2.3e-15 57.7 13.9 5.7 3 2 0 3 3 2 1 AAA domain AAA_15 PF13175.6 CEH18097.1 - 8e-07 29.1 3.9 3.2e-05 23.8 0.0 3.0 2 2 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CEH18097.1 - 0.0029 17.3 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CEH18097.1 - 0.0035 17.2 2.2 0.0091 15.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 CEH18097.1 - 0.073 12.6 0.0 0.073 12.6 0.0 4.6 4 3 3 8 8 8 0 AAA domain AAA_25 PF13481.6 CEH18097.1 - 0.084 12.4 1.4 0.52 9.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEH18097.1 - 0.13 12.7 0.6 1.2 9.6 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CEH18097.1 - 0.13 12.8 0.0 0.13 12.8 0.0 4.4 3 2 0 3 3 2 0 ABC transporter ATP_bind_1 PF03029.17 CEH18097.1 - 0.46 10.2 3.7 2.1 8.1 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Baculo_PEP_C PF04513.12 CEH18097.1 - 1.2 9.2 18.3 0.16 12.0 2.4 3.9 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Chitin_synth_1 PF01644.17 CEH18098.1 - 6.5e-79 263.6 0.1 1e-78 262.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CEH18098.1 - 4.8e-30 103.3 0.2 9.6e-30 102.4 0.2 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CEH18098.1 - 6.9e-25 87.7 1.8 1.7e-18 66.6 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CEH18098.1 - 9.9e-06 25.6 7.8 3.7e-05 23.7 7.8 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 TMEM173 PF15009.6 CEH18098.1 - 0.2 10.8 0.8 0.41 9.8 0.8 1.5 1 0 0 1 1 1 0 Transmembrane protein 173 Iwr1 PF08574.10 CEH18099.1 - 7.8e-08 33.2 16.3 7.8e-08 33.2 16.3 4.4 1 1 2 3 3 3 1 Transcription factor Iwr1 Cupin_8 PF13621.6 CEH18100.1 - 1.1e-41 143.3 0.0 1.3e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CEH18100.1 - 0.006 17.0 0.0 0.019 15.4 0.0 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase FAP PF07174.11 CEH18100.1 - 0.031 13.7 0.3 0.05 13.1 0.3 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) zf-C2H2 PF00096.26 CEH18101.1 - 0.0021 18.4 0.4 0.019 15.4 0.4 2.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf_ZIC PF18366.1 CEH18101.1 - 1.2 9.3 5.3 0.4 10.8 1.6 2.0 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 CEH18101.1 - 2.1 9.4 7.8 1.7 9.7 0.1 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Esterase PF00756.20 CEH18102.1 - 0.00016 21.4 0.1 0.00038 20.2 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 CEH18102.1 - 0.003 17.1 0.1 0.0068 15.9 0.1 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Fungal_trans PF04082.18 CEH18104.1 - 2.1e-13 49.9 0.3 2.8e-12 46.2 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Glycos_transf_3 PF00591.21 CEH18106.1 - 8.2e-70 235.3 0.0 7.7e-69 232.1 0.0 2.0 1 1 1 2 2 2 1 Glycosyl transferase family, a/b domain ASFV_J13L PF05568.11 CEH18106.1 - 0.88 9.3 3.3 2 8.1 3.3 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein PDH PF02153.17 CEH18108.1 - 1.1e-20 73.8 0.0 1.8e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 CEH18108.1 - 0.00078 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CEH18108.1 - 0.0095 16.5 0.0 0.026 15.1 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 CEH18108.1 - 0.011 16.5 0.0 0.025 15.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 CEH18108.1 - 0.074 12.7 0.4 0.34 10.5 0.4 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 CEH18108.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ADH_N PF08240.12 CEH18109.1 - 3.1e-30 104.2 2.1 7.2e-30 103.1 2.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEH18109.1 - 6.6e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CEH18109.1 - 2.7e-08 33.6 0.1 7.8e-08 32.0 0.1 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CEH18109.1 - 0.0002 22.4 0.0 0.00045 21.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.16 CEH18109.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CEH18109.1 - 0.03 14.2 0.1 0.063 13.2 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 CEH18109.1 - 0.031 13.9 0.1 0.05 13.2 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 CEH18109.1 - 0.082 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MOZART1 PF12554.8 CEH18109.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Glyco_tran_WecB PF03808.13 CEH18109.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family zf-C2H2 PF00096.26 CEH18110.1 - 1.2e-06 28.7 7.5 0.014 15.8 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 CEH18110.1 - 5.1e-06 26.5 9.0 1.3e-05 25.2 9.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CEH18110.1 - 0.0001 21.5 0.8 0.00022 20.4 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 CEH18110.1 - 0.00012 22.7 9.4 0.13 13.2 0.3 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEH18110.1 - 0.00038 20.7 7.1 0.03 14.6 1.3 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Allexi_40kDa PF05549.11 CEH18110.1 - 0.00071 19.2 0.2 0.00071 19.2 0.2 1.9 2 0 0 2 2 2 1 Allexivirus 40kDa protein zf-C2H2_11 PF16622.5 CEH18110.1 - 0.07 12.9 3.0 0.22 11.3 3.0 1.9 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-met PF12874.7 CEH18110.1 - 0.17 12.3 1.5 3.1 8.3 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CEH18110.1 - 5.1 7.7 15.0 0.57 10.7 1.9 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Chorismate_synt PF01264.21 CEH18111.1 - 1.2e-135 451.5 0.0 2.3e-135 450.5 0.0 1.4 1 1 0 1 1 1 1 Chorismate synthase RE_AccI PF09545.10 CEH18111.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease Ribosomal_60s PF00428.19 CEH18111.1 - 0.42 11.2 5.7 1.1 10.0 5.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DAHP_synth_2 PF01474.16 CEH18112.1 - 9.6e-164 545.0 0.0 1.1e-163 544.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family FAD_binding_3 PF01494.19 CEH18114.1 - 5.3e-69 233.1 0.0 6.7e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CEH18114.1 - 0.0038 16.8 1.1 0.062 12.9 0.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CEH18114.1 - 0.0064 15.2 0.1 0.01 14.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 CEH18114.1 - 0.01 15.1 0.3 0.057 12.6 0.1 2.0 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 CEH18114.1 - 0.017 15.0 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 CEH18114.1 - 0.018 14.3 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEH18114.1 - 0.05 13.0 1.5 0.064 12.6 0.7 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CEH18114.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 CEH18114.1 - 0.15 12.3 0.1 0.53 10.5 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CEH18114.1 - 0.16 11.0 0.5 0.29 10.2 0.5 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CEH18114.1 - 0.2 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 CEH18114.1 - 0.2 11.9 0.1 0.36 11.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 CEH18115.1 - 4.7e-16 59.0 0.2 1.6e-15 57.2 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CEH18115.1 - 3.6e-14 53.1 0.1 2.2e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CEH18115.1 - 1.6e-13 50.4 0.0 2.1e-07 30.4 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 CEH18115.1 - 3.4e-12 45.9 0.0 5.4e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 CEH18115.1 - 4e-10 39.6 0.0 2.1e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 CEH18115.1 - 4e-07 29.7 0.0 6.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CEH18115.1 - 4.2e-05 22.8 0.0 7.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 CEH18115.1 - 0.0012 19.3 0.1 0.021 15.2 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 CEH18115.1 - 0.0062 16.0 0.0 0.026 14.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 CEH18115.1 - 0.012 14.7 0.0 0.17 11.0 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain TPP_enzyme_N PF02776.18 CEH18116.1 - 4e-30 104.7 0.0 8.7e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CEH18116.1 - 1.2e-15 57.6 0.1 1.8e-14 53.8 0.1 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CEH18116.1 - 3.3e-15 56.0 0.2 2.1e-14 53.4 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF922 PF06037.11 CEH18116.1 - 0.097 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) MFS_1 PF07690.16 CEH18117.1 - 8.5e-38 130.2 61.0 8.9e-35 120.2 60.5 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily TMIE PF16038.5 CEH18117.1 - 0.096 12.5 0.1 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 TMIE protein CcmD PF04995.14 CEH18117.1 - 8.9 6.5 7.2 22 5.2 0.8 3.3 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) EPSP_synthase PF00275.20 CEH18118.1 - 6.9e-98 328.1 0.0 1.1e-97 327.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CEH18118.1 - 2.9e-87 292.1 0.2 4.8e-87 291.4 0.2 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CEH18118.1 - 1.6e-44 152.9 0.0 3e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CEH18118.1 - 8.6e-27 94.2 0.0 1.3e-25 90.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 CEH18118.1 - 8e-24 83.7 0.2 1.8e-23 82.6 0.2 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 CEH18118.1 - 4.9e-07 29.7 1.5 1.1e-06 28.6 1.5 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 CEH18118.1 - 2.7e-05 24.2 0.0 6.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 CEH18118.1 - 0.0011 18.6 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CEH18118.1 - 0.018 15.3 0.7 0.43 10.8 0.0 3.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain AAA_16 PF13191.6 CEH18118.1 - 0.03 14.7 0.0 0.42 11.0 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain p450 PF00067.22 CEH18120.1 - 4.7e-79 266.3 0.0 6.4e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Kri1_C PF12936.7 CEH18122.1 - 6.2e-23 80.8 0.0 6.2e-23 80.8 0.0 4.4 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 CEH18122.1 - 1.9e-21 76.5 5.6 1.9e-21 76.5 5.6 4.6 5 0 0 5 5 5 2 KRI1-like family ECH_1 PF00378.20 CEH18123.1 - 1.3e-34 119.6 0.1 2.6e-34 118.6 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEH18123.1 - 7.6e-20 71.7 0.0 5.2e-18 65.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CBM_4_9 PF02018.17 CEH18125.1 - 0.0013 19.0 8.4 0.14 12.5 0.1 4.5 4 0 0 4 4 4 2 Carbohydrate binding domain EB PF01683.18 CEH18125.1 - 1.5 9.1 36.2 3.1 8.2 6.2 3.8 1 1 3 4 4 4 0 EB module PAM2 PF07145.15 CEH18129.1 - 0.014 15.0 0.0 0.048 13.4 0.0 2.0 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Cyd_oper_YbgE PF09600.10 CEH18129.1 - 0.13 12.6 0.3 3.5 8.1 0.1 2.4 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Glyco_hydro_cc PF11790.8 CEH18130.1 - 5.7e-49 166.8 4.9 7.4e-49 166.5 4.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_2_C PF02836.17 CEH18130.1 - 0.00024 20.3 0.7 0.00036 19.7 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain CUTL PF16557.5 CEH18130.1 - 0.034 14.3 2.7 0.22 11.7 2.7 2.3 1 1 1 2 2 2 0 CUT1-like DNA-binding domain of SATB PBD PF00786.28 CEH18132.1 - 0.0067 16.8 0.1 0.016 15.6 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Herpes_gE PF02480.16 CEH18133.1 - 0.013 14.3 0.1 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mid2 PF04478.12 CEH18133.1 - 0.017 15.0 0.2 0.017 15.0 0.2 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor GST_N_3 PF13417.6 CEH18134.1 - 0.0089 16.4 0.0 0.025 15.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CEH18134.1 - 0.025 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 CEH18135.1 - 1.7e-49 168.6 0.0 3.2e-49 167.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.8 CEH18135.1 - 4.2e-43 147.6 0.0 1e-42 146.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.17 CEH18135.1 - 4.3e-32 111.4 0.0 1.2e-31 110.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH18135.1 - 0.0028 16.5 0.0 0.0048 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEH18135.1 - 0.056 13.4 0.2 1.1 9.1 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family SCP2 PF02036.17 CEH18136.1 - 3.6e-19 69.1 0.4 5.9e-19 68.4 0.4 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CEH18136.1 - 0.0012 19.1 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Aa_trans PF01490.18 CEH18139.1 - 1.2e-27 96.7 31.5 1.5e-27 96.4 31.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF996 PF06195.13 CEH18139.1 - 0.023 15.0 2.8 0.023 15.0 2.8 3.8 2 2 0 3 3 3 0 Protein of unknown function (DUF996) DUF5056 PF16479.5 CEH18139.1 - 0.04 14.2 3.3 0.051 13.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) NADH_Oxid_Nqo15 PF11497.8 CEH18139.1 - 0.088 12.8 0.1 4.4 7.4 0.0 2.3 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 p450 PF00067.22 CEH18140.1 - 1.6e-28 99.7 0.0 2e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.11 CEH18141.1 - 5.6e-06 25.5 0.0 9.5e-06 24.7 0.0 1.5 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) DUF5601 PF18151.1 CEH18142.1 - 0.12 12.7 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) His_Phos_2 PF00328.22 CEH18143.1 - 1.1e-05 25.0 0.0 0.049 13.0 0.0 2.7 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.22 CEH18144.1 - 3.3e-15 55.7 0.0 4.9e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEH18144.1 - 2.3e-05 24.0 0.0 3.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEH18144.1 - 0.054 13.5 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_8 PF11835.8 CEH18144.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain SNF5 PF04855.12 CEH18145.1 - 9.3e-41 140.2 0.0 6.1e-40 137.5 0.0 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DUF543 PF04418.12 CEH18146.1 - 0.0022 17.9 1.1 0.0052 16.7 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Ndc1_Nup PF09531.10 CEH18146.1 - 3.8 6.1 8.1 5.7 5.5 8.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phytase-like PF13449.6 CEH18147.1 - 2.4e-32 113.0 0.3 3e-32 112.7 0.3 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.11 CEH18147.1 - 0.11 11.7 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 SdiA-regulated Ssl1 PF04056.14 CEH18148.1 - 0.022 14.6 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Ssl1-like DAD PF02109.16 CEH18149.1 - 1.7e-35 121.6 4.7 1.9e-35 121.5 4.7 1.0 1 0 0 1 1 1 1 DAD family DUF373 PF04123.13 CEH18149.1 - 0.12 11.8 0.2 0.11 11.9 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2838 PF10998.8 CEH18150.1 - 4.6e-36 123.4 9.2 4.6e-36 123.4 9.2 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2838) Pkinase PF00069.25 CEH18151.1 - 1.3e-66 224.6 0.0 1.8e-66 224.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH18151.1 - 6.1e-36 124.0 0.0 8.9e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH18151.1 - 4.7e-12 45.8 0.0 6.9e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEH18151.1 - 0.059 12.3 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CEH18151.1 - 0.073 12.4 0.1 0.29 10.4 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dynactin_p22 PF07426.11 CEH18152.1 - 8.2e-07 29.0 3.1 5.8e-05 23.0 0.1 3.3 3 1 1 4 4 4 2 Dynactin subunit p22 TatD_DNase PF01026.21 CEH18155.1 - 3.5e-14 52.8 0.0 7.1e-13 48.5 0.0 2.1 1 1 0 1 1 1 1 TatD related DNase NYAP_N PF15439.6 CEH18155.1 - 0.014 14.6 0.3 0.021 14.1 0.3 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter FRG2 PF15315.6 CEH18155.1 - 0.036 14.3 0.2 0.036 14.3 0.2 1.9 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Sdh5 PF03937.16 CEH18156.1 - 2.9e-24 84.8 0.6 4.9e-24 84.1 0.6 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Mannosyl_trans2 PF04188.13 CEH18157.1 - 1.4e-21 77.4 4.3 4.1e-19 69.2 4.3 2.7 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) RhoGAP PF00620.27 CEH18158.1 - 2.6e-17 63.0 0.0 3.9e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Homeodomain PF00046.29 CEH18161.1 - 1.1e-18 66.8 0.8 1.8e-18 66.1 0.8 1.3 1 0 0 1 1 1 1 Homeodomain DUF4614 PF15391.6 CEH18163.1 - 0.029 14.4 0.4 0.029 14.4 0.4 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4614) PAS PF00989.25 CEH18163.1 - 0.084 12.9 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold Zn_clus PF00172.18 CEH18163.1 - 0.22 11.7 1.0 0.61 10.3 1.0 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF262 PF03235.14 CEH18164.1 - 2.3e-14 54.1 0.0 2.3e-13 50.8 0.0 1.9 1 1 1 2 2 2 2 Protein of unknown function DUF262 LIM PF00412.22 CEH18165.1 - 9.6e-19 67.4 11.4 7.2e-11 42.2 2.1 5.1 5 0 0 5 5 5 3 LIM domain DZR PF12773.7 CEH18165.1 - 0.22 11.6 11.6 1 9.4 0.0 3.2 2 2 0 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 CEH18165.1 - 0.7 9.8 15.5 0.3 11.0 1.8 3.7 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF2685 PF10886.8 CEH18165.1 - 2 8.7 5.9 9.9 6.4 1.6 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2685) GTSE1_N PF15259.6 CEH18166.1 - 0.16 12.2 1.5 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 tRNA-synt_1b PF00579.25 CEH18167.1 - 3.3e-61 207.2 0.0 4.7e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 CEH18167.1 - 0.0013 18.4 0.0 0.0049 16.6 0.0 1.9 2 0 0 2 2 2 1 S4 domain Peptidase_S10 PF00450.22 CEH18170.1 - 3.2e-72 244.2 0.0 3.9e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 CEH18170.1 - 0.07 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CEH18170.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Bot1p PF12298.8 CEH18171.1 - 0.04 14.1 0.3 0.048 13.8 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein CNOT11 PF10155.9 CEH18172.1 - 8.1e-06 26.0 0.1 8.8e-05 22.7 0.1 2.2 1 1 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 DCP2 PF05026.13 CEH18173.1 - 2.2e-25 88.8 0.0 3.5e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 CEH18173.1 - 1.4e-15 57.5 0.0 3.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Sde2_N_Ubi PF13019.6 CEH18174.1 - 1.2e-39 135.7 1.9 1.2e-39 135.7 1.9 1.7 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain ATP_bind_1 PF03029.17 CEH18175.1 - 4.4e-82 275.5 0.0 5.2e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CEH18175.1 - 1.3e-05 25.7 1.4 6.3e-05 23.4 0.7 2.7 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 CEH18175.1 - 0.00043 20.6 0.2 0.0013 19.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain CLP1_P PF16575.5 CEH18175.1 - 0.00052 19.9 0.0 0.0029 17.4 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 CEH18175.1 - 0.00057 19.9 0.0 0.0007 19.6 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 CEH18175.1 - 0.0007 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 CEH18175.1 - 0.0011 19.5 0.0 0.0025 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 CEH18175.1 - 0.0021 17.6 0.0 1.8 8.1 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain cobW PF02492.19 CEH18175.1 - 0.0022 17.6 0.1 0.079 12.5 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CEH18175.1 - 0.0022 17.7 0.2 0.004 16.9 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 CEH18175.1 - 0.0027 17.5 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CEH18175.1 - 0.0027 17.3 0.2 0.036 13.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEH18175.1 - 0.0028 17.4 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CEH18175.1 - 0.0058 16.7 0.0 0.073 13.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_35 PF14516.6 CEH18175.1 - 0.0096 14.8 0.0 2.7 6.7 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_14 PF13173.6 CEH18175.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEH18175.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 CEH18175.1 - 0.016 15.1 0.1 0.023 14.6 0.1 1.5 1 1 0 1 1 1 0 NTPase ABC_tran PF00005.27 CEH18175.1 - 0.019 15.5 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 CEH18175.1 - 0.024 15.0 0.0 0.08 13.3 0.0 1.9 2 0 0 2 2 1 0 RNA helicase MeaB PF03308.16 CEH18175.1 - 0.025 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 CEH18175.1 - 0.029 14.4 0.0 0.24 11.4 0.0 2.3 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 CEH18175.1 - 0.032 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 CEH18175.1 - 0.033 14.6 0.1 0.12 12.8 0.0 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CEH18175.1 - 0.037 13.6 0.0 0.037 13.6 0.0 2.2 3 0 0 3 3 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 CEH18175.1 - 0.047 12.9 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 CEH18175.1 - 0.064 13.2 0.3 0.84 9.5 0.1 2.5 3 0 0 3 3 3 0 RsgA GTPase AAA_19 PF13245.6 CEH18175.1 - 0.07 13.5 0.9 0.54 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_31 PF13614.6 CEH18175.1 - 0.07 13.0 0.1 0.91 9.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.22 CEH18175.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CEH18175.1 - 0.073 13.2 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CEH18175.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.9 CEH18175.1 - 0.081 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 CEH18175.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase IstB_IS21 PF01695.17 CEH18175.1 - 0.13 12.0 0.1 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.13 CEH18175.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CobU PF02283.16 CEH18175.1 - 0.18 11.4 0.1 0.6 9.7 0.0 1.9 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase KH_1 PF00013.29 CEH18177.1 - 2e-87 287.0 26.6 4.1e-13 49.0 0.2 14.3 13 2 0 13 13 13 10 KH domain KH_2 PF07650.17 CEH18177.1 - 1.8e-14 53.3 15.3 0.00063 19.5 0.2 8.5 8 1 1 9 9 9 5 KH domain KH_4 PF13083.6 CEH18177.1 - 1.1e-08 34.8 4.6 0.19 11.6 0.0 6.8 7 0 0 7 7 7 3 KH domain SLS PF14611.6 CEH18177.1 - 1.3e-08 35.0 1.6 0.43 10.4 0.0 6.5 5 2 1 7 7 7 4 Mitochondrial inner-membrane-bound regulator YbbR PF07949.12 CEH18177.1 - 0.0036 17.6 21.2 2 8.8 0.0 7.3 9 0 0 9 9 9 3 YbbR-like protein KH_5 PF13184.6 CEH18177.1 - 0.0066 16.5 4.0 21 5.3 0.0 5.5 6 0 0 6 6 6 1 NusA-like KH domain Calreticulin PF00262.18 CEH18178.1 - 7.6e-162 538.3 8.8 9.8e-162 537.9 8.8 1.1 1 0 0 1 1 1 1 Calreticulin family CWC25 PF12542.8 CEH18178.1 - 3 8.8 7.7 0.091 13.7 1.0 1.9 2 0 0 2 2 2 0 Pre-mRNA splicing factor Arm PF00514.23 CEH18179.1 - 2.6e-73 240.1 25.7 9.7e-12 44.5 0.1 11.3 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEH18179.1 - 2.3e-15 56.7 20.9 0.00096 19.6 0.2 8.9 7 3 3 10 10 10 5 HEAT-like repeat HEAT_2 PF13646.6 CEH18179.1 - 2.9e-15 56.4 10.4 0.008 16.5 0.0 7.2 3 2 4 7 7 7 4 HEAT repeats Arm_2 PF04826.13 CEH18179.1 - 1.5e-10 41.0 4.6 8.8e-07 28.6 1.0 2.6 1 1 0 2 2 2 2 Armadillo-like HEAT PF02985.22 CEH18179.1 - 2.1e-10 39.9 21.8 0.86 10.0 0.0 9.9 11 0 0 11 11 10 4 HEAT repeat Adaptin_N PF01602.20 CEH18179.1 - 5.8e-10 38.3 7.7 1.3e-07 30.6 0.1 2.8 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.12 CEH18179.1 - 2.4e-09 35.9 0.1 5.1e-09 34.9 0.1 1.3 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 CEH18179.1 - 7.3e-08 32.1 3.4 0.0039 16.5 1.2 4.4 1 1 3 4 4 4 3 V-ATPase subunit H DUF3361 PF11841.8 CEH18179.1 - 5.5e-07 29.6 4.3 0.041 13.8 0.1 4.5 3 1 1 4 4 4 2 Domain of unknown function (DUF3361) Cnd1 PF12717.7 CEH18179.1 - 2.1e-05 24.6 5.1 0.13 12.3 0.1 4.2 2 2 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 CEH18179.1 - 0.00049 19.6 4.0 6.8 6.0 0.5 4.3 2 1 2 4 4 4 1 Family of unknown function (DUF5578) IFRD PF05004.13 CEH18179.1 - 0.001 18.3 0.8 0.66 9.0 0.1 3.9 3 1 1 4 4 4 1 Interferon-related developmental regulator (IFRD) V-ATPase_H_C PF11698.8 CEH18179.1 - 0.0015 18.6 1.8 18 5.5 0.1 5.0 3 1 3 6 6 6 0 V-ATPase subunit H Proteasom_PSMB PF10508.9 CEH18179.1 - 0.018 13.5 1.2 8.9 4.7 0.0 3.1 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Atx10homo_assoc PF09759.9 CEH18179.1 - 0.1 12.7 3.4 1.4 9.0 0.0 3.7 3 1 0 4 4 3 0 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 CEH18179.1 - 0.1 13.3 10.6 1.1e+02 3.9 0.0 7.4 9 0 0 9 9 7 0 PBS lyase HEAT-like repeat YqfD PF06898.11 CEH18179.1 - 0.2 10.4 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD SH3_1 PF00018.28 CEH18180.1 - 5.9e-23 80.2 0.0 3e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CEH18180.1 - 6.7e-15 54.7 0.0 1.4e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CEH18180.1 - 7.2e-13 48.0 0.0 2e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 CEH18180.1 - 1.1e-06 28.6 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 CEH18180.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 PB1 domain S4 PF01479.25 CEH18182.1 - 3.6e-09 36.2 0.0 6.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain RR_TM4-6 PF06459.12 CEH18182.1 - 0.6 9.9 5.7 0.9 9.3 5.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Red1 PF07964.11 CEH18182.1 - 1.3 7.2 5.7 1.7 6.8 5.7 1.1 1 0 0 1 1 1 0 Rec10 / Red1 S-AdoMet_synt_C PF02773.16 CEH18183.1 - 7.3e-66 220.4 1.4 1.2e-65 219.7 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CEH18183.1 - 1.8e-46 157.3 0.0 3.7e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CEH18183.1 - 8.4e-45 151.5 1.4 8.4e-45 151.5 0.2 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 CEH18183.1 - 0.026 13.3 0.3 0.17 10.6 0.1 2.1 2 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) adh_short PF00106.25 CEH18184.1 - 5.6e-22 78.2 0.0 2.6e-19 69.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEH18184.1 - 2.5e-12 46.9 0.0 4.8e-12 46.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH18184.1 - 0.0019 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain USP7_ICP0_bdg PF12436.8 CEH18189.1 - 6.9e-88 294.0 1.1 1.2e-87 293.2 0.7 1.6 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 CEH18189.1 - 4.9e-64 215.8 1.9 1.8e-62 210.7 0.2 3.0 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 CEH18189.1 - 4.1e-49 167.4 0.0 6.2e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEH18189.1 - 4.4e-21 75.8 0.0 8.5e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 CEH18189.1 - 1.2e-09 38.3 0.2 6.9e-09 35.9 0.0 2.3 3 0 0 3 3 3 1 MATH domain F-box-like PF12937.7 CEH18189.1 - 0.0025 17.7 0.0 0.0064 16.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Rad60-SLD PF11976.8 CEH18189.1 - 0.16 11.9 0.1 1.7 8.6 0.0 2.8 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like CAMSAP_CC1 PF17095.5 CEH18189.1 - 5.5 6.9 6.7 16 5.5 6.7 1.7 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin SIR2 PF02146.17 CEH18190.1 - 7.6e-22 78.1 0.0 1.3e-20 74.0 0.0 2.4 2 0 0 2 2 2 1 Sir2 family Macro PF01661.21 CEH18191.1 - 1.1e-40 138.4 0.0 2.9e-40 137.0 0.1 1.6 2 0 0 2 2 2 1 Macro domain E1-E2_ATPase PF00122.20 CEH18192.1 - 2.6e-44 150.9 0.4 1e-40 139.2 0.0 3.7 3 1 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 CEH18192.1 - 3.3e-17 63.5 0.1 6.6e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEH18192.1 - 2.5e-10 39.9 0.0 5.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEH18192.1 - 0.002 17.9 0.1 0.0039 17.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase YrvL PF14184.6 CEH18192.1 - 2.8 8.1 11.4 0.074 13.2 4.0 2.2 2 0 0 2 2 2 0 Regulatory protein YrvL Glyoxalase PF00903.25 CEH18193.1 - 7.6e-06 26.1 0.0 3.3e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Adeno_IVa2 PF02456.15 CEH18193.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein FAD_binding_7 PF03441.14 CEH18194.1 - 5e-72 241.6 2.4 7.7e-72 241.0 2.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CEH18194.1 - 5e-35 120.9 0.0 9.8e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase N_NLPC_P60 PF12912.7 CEH18194.1 - 0.034 14.5 1.4 0.46 10.9 0.2 2.5 2 0 0 2 2 2 0 NLPC_P60 stabilising domain, N term Usp PF00582.26 CEH18194.1 - 0.34 11.4 4.0 1.2 9.6 0.1 2.7 2 1 0 2 2 2 0 Universal stress protein family Nnf1 PF03980.14 CEH18196.1 - 1.1e-06 28.9 4.0 1.1e-06 28.9 4.0 2.2 2 0 0 2 2 2 1 Nnf1 Rb_C PF08934.10 CEH18196.1 - 0.077 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Rb C-terminal domain KxDL PF10241.9 CEH18196.1 - 0.51 10.7 2.2 2.6 8.4 0.8 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein Methyltransf_31 PF13847.6 CEH18197.1 - 2.7e-05 24.0 0.4 0.00013 21.8 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CEH18197.1 - 0.00014 21.5 0.3 0.0025 17.4 0.3 2.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CEH18197.1 - 0.0022 18.7 0.7 0.0063 17.2 0.1 2.2 2 2 0 2 2 2 1 Methyltransferase domain PrmC_N PF17827.1 CEH18197.1 - 0.0045 17.5 0.4 0.12 13.0 1.1 2.9 2 1 0 2 2 2 1 PrmC N-terminal domain Methyltransf_32 PF13679.6 CEH18197.1 - 0.011 15.7 1.3 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain N6_Mtase PF02384.16 CEH18197.1 - 0.034 13.4 0.0 0.076 12.3 0.0 1.5 2 0 0 2 2 2 0 N-6 DNA Methylase N6-adenineMlase PF10237.9 CEH18197.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase UPF0020 PF01170.18 CEH18197.1 - 0.14 11.8 0.2 2 8.1 0.2 2.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Sec66 PF09802.9 CEH18198.1 - 1.7e-24 86.4 1.1 2.1e-24 86.1 0.1 1.5 2 0 0 2 2 2 1 Preprotein translocase subunit Sec66 DUF2336 PF10098.9 CEH18198.1 - 0.024 14.1 2.4 0.51 9.8 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) Acyl-CoA_dh_1 PF00441.24 CEH18200.1 - 1.4e-27 96.8 0.7 2.8e-27 95.8 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEH18200.1 - 6.8e-24 83.9 0.0 1.4e-17 63.7 0.0 2.6 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEH18200.1 - 9.1e-13 48.6 1.1 1.8e-12 47.7 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEH18200.1 - 3.6e-10 40.5 0.0 7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain SpoIIM PF01944.17 CEH18201.1 - 0.03 14.4 2.0 0.038 14.0 2.0 1.3 1 1 0 1 1 1 0 Stage II sporulation protein M EBP PF05241.12 CEH18201.1 - 3.8 7.0 10.9 52 3.2 10.9 2.1 1 1 0 1 1 1 0 Emopamil binding protein Actin PF00022.19 CEH18202.1 - 1.3e-109 366.6 0.0 1e-108 363.6 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CEH18202.1 - 0.0057 15.5 0.0 0.028 13.3 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein TMEM51 PF15345.6 CEH18203.1 - 0.0083 16.0 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 DUF2070 PF09843.9 CEH18203.1 - 5.3 5.2 6.1 8.1 4.6 6.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RabGAP-TBC PF00566.18 CEH18204.1 - 1.7e-46 158.6 0.0 2.3e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.28 CEH18204.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEH18204.1 - 0.073 12.8 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain DUF2256 PF10013.9 CEH18206.1 - 3.9e-12 46.1 5.4 6.6e-12 45.4 5.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) PLATZ PF04640.14 CEH18206.1 - 0.015 15.9 1.5 0.034 14.8 1.5 1.6 1 0 0 1 1 1 0 PLATZ transcription factor zf-FCS PF06467.14 CEH18206.1 - 0.097 12.6 3.7 0.31 11.0 3.7 1.9 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-FLZ PF04570.14 CEH18206.1 - 0.29 10.6 1.2 1 8.9 1.2 1.9 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Pkinase PF00069.25 CEH18207.1 - 2.6e-50 171.2 0.0 5.6e-30 104.6 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CEH18207.1 - 3.2e-24 85.6 0.0 2.9e-19 69.4 0.0 3.5 4 0 0 4 4 4 3 Protein tyrosine kinase Kinase-like PF14531.6 CEH18207.1 - 5.6e-05 22.6 0.0 0.25 10.6 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 CEH18207.1 - 0.0078 15.0 1.1 0.02 13.7 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEH18207.1 - 0.028 14.3 0.0 0.028 14.3 0.0 3.0 4 0 0 4 4 4 0 Phosphotransferase enzyme family Kdo PF06293.14 CEH18207.1 - 0.16 11.3 0.2 0.52 9.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TauD PF02668.16 CEH18210.1 - 8e-50 170.1 1.1 1.3e-49 169.4 1.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mu-like_Pro PF10123.9 CEH18211.1 - 0.015 14.9 0.4 0.015 14.9 0.4 1.0 1 0 0 1 1 1 0 Mu-like prophage I protein Aft1_HRA PF11786.8 CEH18212.1 - 6e-22 77.8 8.6 6e-22 77.8 8.6 2.9 3 2 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.21 CEH18212.1 - 1.8e-12 47.1 7.0 2.6e-12 46.7 7.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CEH18212.1 - 8.7e-07 28.9 9.9 1.2e-06 28.5 9.4 1.4 1 1 0 1 1 1 1 Basic region leucine zipper THOC7 PF05615.13 CEH18212.1 - 0.016 15.5 0.7 0.02 15.2 0.7 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 bZIP_Maf PF03131.17 CEH18212.1 - 0.22 12.1 6.1 0.34 11.5 6.1 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4407 PF14362.6 CEH18212.1 - 0.41 9.9 1.5 0.73 9.1 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phlebovirus_NSM PF07246.11 CEH18212.1 - 0.49 9.7 1.5 0.68 9.3 1.5 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Chitin_synth_1 PF01644.17 CEH18213.1 - 3.4e-72 241.8 0.0 5.1e-72 241.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CEH18213.1 - 2.1e-27 94.9 0.0 3.5e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CEH18213.1 - 7e-25 87.6 0.1 8.8e-19 67.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CEH18213.1 - 3.5e-10 40.1 0.4 3.5e-10 40.1 0.4 1.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 zf-HIT PF04438.16 CEH18214.1 - 1.9e-07 30.8 7.4 2.9e-07 30.2 7.4 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-CCHC_4 PF14392.6 CEH18214.1 - 0.97 9.2 9.3 0.3 10.9 2.1 2.2 1 1 1 2 2 2 0 Zinc knuckle DUF4834 PF16118.5 CEH18215.1 - 0.0042 18.0 0.3 0.0063 17.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Insulin_TMD PF17870.1 CEH18215.1 - 0.02 15.0 0.6 0.032 14.3 0.6 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DivIC PF04977.15 CEH18215.1 - 6.2 6.7 6.9 16 5.3 0.2 2.1 2 0 0 2 2 2 0 Septum formation initiator PP2C PF00481.21 CEH18216.1 - 2e-49 168.6 0.7 4.7e-49 167.3 0.7 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 CEH18216.1 - 1.8e-42 142.9 64.4 3e-08 33.3 0.3 10.3 8 2 3 11 11 11 8 Leucine rich repeat LRR_4 PF12799.7 CEH18216.1 - 1.6e-39 133.3 63.6 2.9e-05 24.3 1.7 13.1 8 3 7 15 15 15 14 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 CEH18216.1 - 1.9e-24 86.3 0.0 3.7e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 CEH18216.1 - 1.4e-07 31.2 20.1 0.046 13.2 0.3 5.2 2 1 3 5 5 5 3 Leucine-rich repeat LRR_5 PF13306.6 CEH18216.1 - 0.0042 17.0 5.2 8.6 6.3 0.1 4.1 1 1 3 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CEH18216.1 - 0.0053 17.1 46.1 20 6.2 0.1 14.8 15 2 0 15 15 15 1 Leucine Rich Repeat PP2C_2 PF13672.6 CEH18216.1 - 0.024 14.3 0.1 0.056 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C ENTH PF01417.20 CEH18217.1 - 5e-47 159.0 0.5 8.2e-47 158.3 0.1 1.6 2 0 0 2 2 2 1 ENTH domain UIM PF02809.20 CEH18217.1 - 0.003 17.4 13.5 0.0059 16.5 0.5 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif ANTH PF07651.16 CEH18217.1 - 0.0052 15.8 0.3 0.0093 15.0 0.2 1.6 1 1 0 1 1 1 1 ANTH domain VIR_N PF15912.5 CEH18217.1 - 1.3 8.6 0.0 1.3 8.6 0.0 2.5 3 0 0 3 3 3 0 Virilizer, N-terminal CDC27 PF09507.10 CEH18217.1 - 2.3 7.5 17.1 4.2 6.7 17.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_17 PF13207.6 CEH18217.1 - 3.1 8.2 7.9 2.5 8.5 4.2 2.3 2 0 0 2 2 2 0 AAA domain Paf1 PF03985.13 CEH18218.1 - 2.5e-43 148.7 12.5 1.5e-42 146.1 12.5 2.1 1 1 0 1 1 1 1 Paf1 ATG13 PF10033.9 CEH18219.1 - 4.7e-32 111.6 0.0 7.2e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 PIN_4 PF13638.6 CEH18220.1 - 6.9e-19 68.4 0.0 1.5e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 CEH18220.1 - 3.1e-09 36.7 0.0 8.6e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain PIN_9 PF18477.1 CEH18220.1 - 0.04 14.2 0.1 0.67 10.3 0.1 2.4 2 0 0 2 2 2 0 PIN like domain 2_5_RNA_ligase2 PF13563.6 CEH18222.1 - 2.6e-17 63.2 0.7 6.5e-07 29.4 0.1 3.1 3 0 0 3 3 3 3 2'-5' RNA ligase superfamily WLM PF08325.10 CEH18225.1 - 3.8e-30 105.4 3.2 3.8e-30 105.4 3.2 2.3 2 1 0 2 2 2 1 WLM domain zf-RanBP PF00641.18 CEH18225.1 - 0.00039 19.7 7.4 0.001 18.3 7.4 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 CEH18225.1 - 0.00053 20.1 1.7 0.0015 18.6 1.7 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 Gly_acyl_tr_N PF06021.11 CEH18226.1 - 0.032 14.3 2.8 0.065 13.3 2.8 1.4 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase UPF0147 PF03685.13 CEH18226.1 - 0.089 12.9 0.8 0.27 11.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) Herpes_capsid PF06112.11 CEH18226.1 - 1.8 8.6 12.9 7.3 6.6 12.9 2.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein BST2 PF16716.5 CEH18226.1 - 9.7 6.9 11.7 2 9.0 4.5 3.5 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 LUC7 PF03194.15 CEH18227.1 - 6.9e-62 209.4 3.6 5e-60 203.3 3.6 2.2 1 1 0 1 1 1 1 LUC7 N_terminus TORC_N PF12884.7 CEH18227.1 - 0.068 14.0 0.3 0.13 13.1 0.3 1.5 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus Auts2 PF15336.6 CEH18227.1 - 1.3 9.1 10.0 0.14 12.3 5.1 1.8 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein PPR PF01535.20 CEH18229.1 - 9.4e-10 38.1 0.2 0.089 13.1 0.0 5.5 5 0 0 5 5 5 3 PPR repeat PPR_2 PF13041.6 CEH18229.1 - 1.3e-09 38.0 0.0 0.048 13.9 0.0 5.5 8 0 0 8 8 8 3 PPR repeat family PPR_3 PF13812.6 CEH18229.1 - 0.0013 18.8 0.0 0.54 10.4 0.0 3.5 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 CEH18229.1 - 0.024 14.3 0.1 0.88 9.3 0.0 3.4 2 0 0 2 2 2 0 PPR repeat ATP-synt PF00231.19 CEH18230.1 - 1.7e-54 185.5 7.5 5.5e-41 141.1 1.4 2.0 1 1 1 2 2 2 2 ATP synthase MFS_1 PF07690.16 CEH18231.1 - 7.5e-16 58.0 48.3 1.1e-15 57.4 34.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily RA PF00788.23 CEH18232.1 - 2.6e-14 53.6 0.0 5.5e-10 39.7 0.0 3.1 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 CEH18232.1 - 7e-08 32.0 0.0 2.4e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CEH18232.1 - 0.0096 15.8 0.2 0.057 13.3 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain Par3_HAL_N_term PF12053.8 CEH18232.1 - 0.11 12.7 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins DUF155 PF02582.14 CEH18233.1 - 4.8e-50 170.1 0.0 7.3e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Helo_like_N PF17111.5 CEH18233.1 - 0.049 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins ADH_zinc_N PF00107.26 CEH18234.1 - 2.5e-21 76.0 0.1 5.9e-21 74.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CEH18234.1 - 5.9e-17 61.5 0.0 9.7e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 CEH18234.1 - 1.9e-09 38.7 0.0 7.3e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 CEH18234.1 - 0.00042 20.2 0.1 0.32 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2855) UDPGT PF00201.18 CEH18235.1 - 0.028 13.2 0.0 0.075 11.8 0.1 1.6 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 CEH18235.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 CEH18236.1 - 0.2 10.4 0.1 0.24 10.2 0.1 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Tri3 PF07428.11 CEH18237.1 - 0.00022 20.3 0.0 0.00068 18.7 0.0 1.7 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 p450 PF00067.22 CEH18238.1 - 1.2e-53 182.5 0.0 5.4e-42 144.1 0.0 3.6 3 1 0 3 3 3 3 Cytochrome P450 DUF4680 PF15730.5 CEH18238.1 - 0.0087 16.4 3.8 0.02 15.2 3.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4680) AhpC-TSA_2 PF13911.6 CEH18239.1 - 1.1e-08 35.2 0.0 2.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Lon_C PF05362.13 CEH18241.1 - 9.8e-38 129.7 0.1 1.2e-37 129.5 0.1 1.1 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 CEH18241.1 - 1.1e-05 25.2 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Birna_VP4 PF01768.16 CEH18241.1 - 0.014 15.2 0.1 0.018 14.9 0.1 1.1 1 0 0 1 1 1 0 Birnavirus VP4 protein TRI12 PF06609.13 CEH18241.1 - 0.021 13.2 0.0 0.026 13.0 0.0 1.0 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MGC-24 PF05283.11 CEH18242.1 - 3.6 8.0 8.8 5 7.6 8.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PAF-AH_p_II PF03403.13 CEH18244.1 - 7.4e-45 153.1 0.0 6.9e-44 149.9 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 CEH18244.1 - 0.00011 21.2 0.0 0.00023 20.2 0.0 1.4 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 CEH18244.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.8 CEH18244.1 - 0.015 14.5 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH18244.1 - 0.048 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH18244.1 - 0.065 13.8 2.8 0.41 11.2 2.8 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sod_Fe_C PF02777.18 CEH18245.1 - 5.3e-18 65.1 0.0 5.9e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Carboxyl_trans PF01039.22 CEH18247.1 - 2.3e-159 531.2 1.7 5.8e-101 338.6 0.0 2.0 1 1 1 2 2 2 2 Carboxyl transferase domain MdcE PF06833.11 CEH18247.1 - 0.00047 19.7 1.1 0.027 14.0 0.1 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) ACCA PF03255.14 CEH18247.1 - 0.033 14.1 1.9 8.8 6.2 0.0 2.9 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit S-methyl_trans PF02574.16 CEH18248.1 - 9.2e-50 169.9 0.0 1.5e-48 165.9 0.0 2.0 1 1 0 1 1 1 1 Homocysteine S-methyltransferase GPS PF01825.21 CEH18248.1 - 0.67 10.5 0.1 0.67 10.5 0.1 2.5 2 1 1 3 3 3 0 GPCR proteolysis site, GPS, motif EBP PF05241.12 CEH18249.1 - 4.2e-61 205.5 8.6 5.4e-61 205.1 8.6 1.1 1 0 0 1 1 1 1 Emopamil binding protein ADH_N PF08240.12 CEH18250.1 - 5.5e-28 97.0 0.2 1e-27 96.2 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEH18250.1 - 3e-22 79.0 0.0 5.5e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CEH18250.1 - 1.6e-08 34.3 0.1 0.00085 18.9 0.0 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CEH18250.1 - 2.9e-05 25.1 0.0 5.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 CEH18250.1 - 0.022 14.3 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 CEH18250.1 - 0.024 13.9 0.0 0.047 12.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CEH18250.1 - 0.071 12.4 0.4 0.13 11.6 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 CEH18250.1 - 0.11 13.3 0.0 0.33 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.6 CEH18250.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fe_hyd_lg_C PF02906.14 CEH18251.1 - 2.4e-55 187.8 0.0 5.5e-55 186.7 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain BTB PF00651.31 CEH18252.1 - 0.049 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Scramblase PF03803.15 CEH18253.1 - 6.1e-51 172.8 0.0 8.1e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Scramblase CENP-U PF13097.6 CEH18253.1 - 2.3 8.2 4.0 3.8 7.4 4.0 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DAO PF01266.24 CEH18254.1 - 6e-37 128.0 1.1 7.8e-37 127.7 1.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEH18254.1 - 0.00053 20.0 0.7 0.0011 18.9 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CEH18254.1 - 0.0012 19.1 0.1 0.0042 17.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain APG12 PF04110.13 CEH18255.1 - 5.3e-30 103.7 0.0 6.2e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 CEH18255.1 - 0.0041 17.3 0.0 0.005 17.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Acyltransferase PF01553.21 CEH18256.1 - 2.4e-33 114.6 0.0 4.2e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase ChpXY PF10216.9 CEH18256.1 - 0.23 10.5 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) Ribonuclease_3 PF00636.26 CEH18257.1 - 4.6e-34 117.2 0.0 3.3e-18 66.2 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 CEH18257.1 - 4.3e-19 68.5 0.1 4.8e-18 65.1 0.0 2.5 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 CEH18257.1 - 2.3e-14 53.6 0.0 8.2e-09 35.7 0.0 3.5 2 1 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 CEH18257.1 - 3.1e-13 50.0 0.0 2.9e-11 43.7 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEH18257.1 - 1.5e-11 44.4 0.0 2.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CEH18257.1 - 5.9e-11 42.7 0.0 1.2e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 CEH18257.1 - 0.046 14.4 0.0 8.1 7.2 0.0 2.8 2 0 0 2 2 2 0 Double-stranded RNA binding motif Strumpellin PF10266.9 CEH18257.1 - 0.052 11.2 0.0 0.077 10.7 0.0 1.1 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin Forkhead PF00250.18 CEH18258.1 - 3.5e-14 52.8 0.0 6.1e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CEH18258.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Ytp1 PF10355.9 CEH18259.1 - 2.1e-101 338.8 0.2 3.2e-101 338.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CEH18259.1 - 7.9e-18 64.2 0.7 7.9e-18 64.2 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) adh_short PF00106.25 CEH18260.1 - 1.4e-18 67.1 0.9 1e-09 38.2 0.7 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEH18260.1 - 1.2e-08 34.8 1.4 0.0028 17.2 1.9 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH18260.1 - 0.00027 20.9 0.0 0.00054 19.9 0.0 1.5 1 0 0 1 1 1 1 KR domain CEND1 PF15677.5 CEH18261.1 - 3.5 8.2 12.4 4.5 7.8 12.4 1.1 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Ribosomal_S3Ae PF01015.18 CEH18262.1 - 7.5e-91 303.2 0.7 8.8e-91 303.0 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 CEH18262.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region RRM_1 PF00076.22 CEH18263.1 - 1.6e-14 53.5 0.0 2.6e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CEH18263.1 - 5.4e-09 36.5 1.9 5.4e-09 36.5 1.9 2.6 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 MFS_1 PF07690.16 CEH18265.1 - 1.2e-29 103.4 17.9 1.2e-29 103.4 17.9 2.8 2 2 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH18265.1 - 6.8e-12 45.0 0.4 6.8e-12 45.0 0.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4381 PF14316.6 CEH18265.1 - 0.02 15.1 2.3 0.067 13.4 2.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PsbY PF06298.11 CEH18267.1 - 0.0042 17.0 0.6 0.0059 16.5 0.6 1.2 1 0 0 1 1 1 1 Photosystem II protein Y (PsbY) Diphthamide_syn PF01866.17 CEH18268.1 - 1.2e-78 264.6 0.0 4.4e-77 259.5 0.0 2.1 1 1 0 1 1 1 1 Putative diphthamide synthesis protein WD40 PF00400.32 CEH18269.1 - 1.1e-07 32.4 3.7 0.0053 17.6 0.2 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CEH18269.1 - 0.0094 14.9 0.0 0.32 9.9 0.0 2.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 CEH18269.1 - 0.021 15.1 0.1 19 5.6 0.0 3.8 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEH18269.1 - 0.12 11.0 1.5 8.2 4.9 0.1 2.5 1 1 2 3 3 3 0 Nucleoporin Nup120/160 GA PF01468.17 CEH18270.1 - 0.058 13.7 0.2 0.2 12.0 0.2 2.0 1 0 0 1 1 1 0 GA module PhageMin_Tail PF10145.9 CEH18270.1 - 0.085 12.7 0.1 0.085 12.7 0.1 2.0 2 0 0 2 2 2 0 Phage-related minor tail protein Histidinol_dh PF00815.20 CEH18272.1 - 5.2e-156 519.8 0.7 1.2e-155 518.5 0.7 1.6 1 1 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 CEH18272.1 - 7.6e-23 80.1 0.1 1.4e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 CEH18272.1 - 1.9e-12 47.4 0.1 5.8e-12 45.9 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 CEH18272.1 - 0.0058 16.8 1.1 0.0084 16.3 0.1 1.9 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain Peptidase_S28 PF05577.12 CEH18274.1 - 4.5e-42 144.4 0.0 1.6e-41 142.5 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Actin PF00022.19 CEH18275.1 - 8.1e-112 373.8 0.0 9.7e-112 373.5 0.0 1.1 1 0 0 1 1 1 1 Actin XPG_N PF00752.17 CEH18276.1 - 3.2e-31 107.8 0.0 8.3e-31 106.5 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CEH18276.1 - 2.7e-26 91.7 0.0 6.7e-26 90.5 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 CEH18276.1 - 2e-06 27.5 0.0 7.5e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 XPG domain containing ADH_zinc_N PF00107.26 CEH18277.1 - 4.5e-07 29.9 0.0 7.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CEH18277.1 - 0.00018 21.4 0.0 0.00048 20.0 0.0 1.6 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_N PF08240.12 CEH18277.1 - 0.002 18.0 0.0 0.0081 16.0 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CEH18277.1 - 0.14 13.2 0.0 0.31 12.1 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase GHMP_kinases_C PF08544.13 CEH18277.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 GHMP kinases C terminal DLH PF01738.18 CEH18278.1 - 4.9e-05 23.0 0.0 0.0045 16.6 0.1 2.0 1 1 1 2 2 2 2 Dienelactone hydrolase family B56 PF01603.20 CEH18280.1 - 1.5e-49 169.1 2.1 1.6e-49 169.0 2.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.20 CEH18281.1 - 3.9e-120 401.6 7.2 3.5e-80 270.0 0.3 2.1 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) EOS1 PF12326.8 CEH18282.1 - 2.3e-51 174.2 0.0 4.7e-51 173.2 0.0 1.5 1 0 0 1 1 1 1 N-glycosylation protein Usp PF00582.26 CEH18283.1 - 4e-15 56.6 0.3 6.4e-15 55.9 0.3 1.4 1 0 0 1 1 1 1 Universal stress protein family RasGAP PF00616.19 CEH18285.1 - 3.2e-47 160.9 0.1 1e-46 159.3 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 CEH18285.1 - 1.5e-46 158.0 3.9 1.5e-46 158.0 3.9 2.2 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 CEH18285.1 - 4e-24 82.1 27.6 0.015 15.0 0.2 10.0 9 0 0 9 9 9 9 IQ calmodulin-binding motif CH PF00307.31 CEH18285.1 - 4e-14 52.7 0.0 8.7e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Paz_1 PF18349.1 CEH18285.1 - 0.061 13.3 0.0 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 PAZ domain Borrelia_P83 PF05262.11 CEH18285.1 - 0.25 9.8 11.5 0.41 9.1 11.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein LysM PF01476.20 CEH18286.1 - 0.00071 19.6 0.1 0.0026 17.8 0.1 1.9 2 0 0 2 2 2 1 LysM domain zf-RING_10 PF16685.5 CEH18286.1 - 0.023 14.8 3.5 0.023 14.8 3.5 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 Baculo_IE-1 PF05290.11 CEH18286.1 - 0.073 13.0 0.8 0.13 12.2 0.8 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) SNF2_N PF00176.23 CEH18287.1 - 2e-75 253.7 0.0 4.1e-75 252.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CEH18287.1 - 2.8e-37 127.2 2.1 8e-37 125.7 0.3 2.7 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 CEH18287.1 - 1.2e-30 106.6 6.4 1.2e-30 106.6 6.4 3.8 4 1 0 4 4 2 1 HAND Helicase_C PF00271.31 CEH18287.1 - 9.5e-21 74.2 0.1 1.8e-17 63.7 0.0 3.5 4 0 0 4 4 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CEH18287.1 - 1e-10 41.9 0.0 1e-09 38.6 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 CEH18287.1 - 2e-06 27.9 0.3 0.011 15.9 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 CEH18287.1 - 7.3e-06 25.4 1.0 2.1e-05 23.9 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CEH18287.1 - 9.7e-06 25.5 0.0 2.7e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 CEH18287.1 - 8.9e-05 22.9 4.1 8.9e-05 22.9 4.1 3.4 3 1 1 4 4 3 1 DNA-binding domain AAA_14 PF13173.6 CEH18287.1 - 0.0054 16.8 1.7 0.044 13.8 0.0 3.3 3 1 0 3 3 3 1 AAA domain ERCC3_RAD25_C PF16203.5 CEH18287.1 - 0.017 14.4 0.1 0.017 14.4 0.1 2.5 3 1 1 4 4 4 0 ERCC3/RAD25/XPB C-terminal helicase UPF0261 PF06792.11 CEH18287.1 - 0.059 12.3 0.2 0.37 9.7 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0261) AAA_22 PF13401.6 CEH18287.1 - 0.2 11.9 1.9 0.88 9.8 0.0 2.9 3 1 0 3 3 3 0 AAA domain Cyclin_N PF00134.23 CEH18289.1 - 3e-44 149.8 0.2 6.7e-41 139.0 0.3 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEH18289.1 - 3.1e-27 95.0 0.0 6.4e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Romo1 PF10247.9 CEH18291.1 - 3.8e-23 81.6 16.1 4.8e-23 81.3 16.1 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Na_H_antiport_1 PF06965.12 CEH18291.1 - 0.07 12.0 2.2 0.079 11.8 2.2 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter 1 DHHA2 PF02833.14 CEH18292.1 - 1.8e-19 70.3 0.0 3.2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CEH18292.1 - 9.2e-09 35.5 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 DHH family polyprenyl_synt PF00348.17 CEH18293.1 - 1.3e-64 217.7 0.0 8.3e-57 192.2 0.0 2.6 2 1 0 2 2 2 2 Polyprenyl synthetase NUDIX PF00293.28 CEH18294.1 - 4.3e-12 46.2 0.3 8.1e-12 45.3 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain Hydrolase_4 PF12146.8 CEH18295.1 - 2.4e-06 27.0 0.0 0.052 12.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Pkinase_Tyr PF07714.17 CEH18298.1 - 5.4e-44 150.4 0.0 7.6e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEH18298.1 - 1.5e-41 142.5 0.0 2.2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SAP PF02037.27 CEH18298.1 - 0.00062 19.5 0.1 0.0016 18.2 0.1 1.8 1 0 0 1 1 1 1 SAP domain Serglycin PF04360.12 CEH18298.1 - 0.11 12.5 4.1 2.1 8.3 0.0 3.3 3 0 0 3 3 3 0 Serglycin Haspin_kinase PF12330.8 CEH18298.1 - 0.14 11.1 0.1 0.25 10.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CEH18298.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Peptidase_M20 PF01546.28 CEH18299.1 - 1.4e-34 119.7 0.0 1.8e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CEH18299.1 - 6.8e-11 42.1 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Ras PF00071.22 CEH18300.1 - 1.5e-52 177.4 0.0 1.9e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH18300.1 - 3.8e-27 94.9 0.0 5.7e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH18300.1 - 1e-11 44.6 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 CEH18300.1 - 1.3e-06 28.0 0.1 1.5e-05 24.6 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CEH18300.1 - 9e-06 25.8 0.0 1.3e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEH18300.1 - 0.00057 19.8 0.0 0.069 13.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CEH18300.1 - 0.0023 17.5 0.1 0.0071 15.9 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CEH18300.1 - 0.079 12.4 0.0 0.24 10.8 0.0 1.7 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CEH18300.1 - 0.099 12.9 0.0 1.1 9.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF4834 PF16118.5 CEH18301.1 - 0.54 11.2 1.3 51 4.9 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MgtC PF02308.16 CEH18301.1 - 2.2 8.6 20.9 0.2 12.0 4.3 2.8 2 1 1 3 3 3 0 MgtC family Pex16 PF08610.10 CEH18302.1 - 6e-114 380.6 0.0 7.3e-114 380.3 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) E1_dh PF00676.20 CEH18303.1 - 6.6e-89 297.8 0.0 8.1e-89 297.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 CEH18303.1 - 0.00023 21.0 0.6 0.0032 17.3 0.6 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 CEH18303.1 - 0.00078 18.7 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase MOSC_N PF03476.16 CEH18304.1 - 6.2e-23 80.9 0.0 1.2e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 CEH18304.1 - 1.1e-15 57.8 0.0 5.6e-15 55.5 0.0 2.1 2 1 0 2 2 2 1 MOSC domain LRR_6 PF13516.6 CEH18305.1 - 1.1e-09 37.5 14.9 0.033 14.2 0.1 7.2 8 0 0 8 8 8 4 Leucine Rich repeat adh_short PF00106.25 CEH18306.1 - 2.6e-23 82.5 0.0 1.1e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEH18306.1 - 1.2e-14 54.5 0.0 6.6e-13 48.8 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH18306.1 - 2.6e-06 27.4 0.0 4.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEH18306.1 - 0.0088 15.5 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 CEH18306.1 - 0.021 14.7 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 YjeF-related protein N-terminus Pyr_redox_3 PF13738.6 CEH18306.1 - 0.034 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 CEH18306.1 - 0.047 14.0 0.0 0.088 13.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 CEH18306.1 - 0.047 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SMC_hinge PF06470.13 CEH18306.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain GCS PF03074.16 CEH18307.1 - 8.6e-175 581.4 0.0 1.1e-174 581.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 CEH18307.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) W2 PF02020.18 CEH18308.1 - 8e-14 51.5 0.0 2.4e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF3081 PF11280.8 CEH18308.1 - 0.13 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) ArfGap PF01412.18 CEH18309.1 - 6.5e-20 71.4 0.1 1.2e-19 70.5 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf HhH-GPD PF00730.25 CEH18311.1 - 4.8e-09 36.6 0.0 7.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SH3BP5 PF05276.14 CEH18311.1 - 0.032 14.0 1.3 0.032 14.0 1.3 1.5 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) DEPP PF15343.6 CEH18311.1 - 0.62 10.1 8.9 0.37 10.8 6.3 1.9 1 1 1 2 2 2 0 Decidual protein induced by progesterone family DUF4770 PF15994.5 CEH18311.1 - 1.1 9.4 5.7 0.91 9.7 4.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4770) Lipase_GDSL_2 PF13472.6 CEH18312.1 - 7.7e-14 52.5 0.0 1.1e-13 51.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CEH18312.1 - 3.5e-09 36.9 0.0 9e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MTBP_C PF14920.6 CEH18313.1 - 0.16 11.7 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 MDM2-binding ALAD PF00490.21 CEH18314.1 - 2e-118 395.2 0.0 2.3e-118 395.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase HP1451_C PF18472.1 CEH18314.1 - 0.052 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 HP1451 C-terminal domain HAGH_C PF16123.5 CEH18315.1 - 2e-19 69.9 0.0 3.5e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CEH18315.1 - 3.7e-11 43.4 2.0 1.2e-10 41.8 2.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEH18315.1 - 0.0052 16.3 0.2 0.088 12.3 0.1 2.7 1 1 1 3 3 3 1 Beta-lactamase superfamily domain FERM_f0 PF16511.5 CEH18315.1 - 0.077 13.3 0.1 5.8 7.3 0.0 2.4 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM LRR_6 PF13516.6 CEH18316.1 - 0.011 15.8 9.0 18 5.7 1.5 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 CEH18316.1 - 0.075 13.6 7.4 13 6.8 0.2 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 CEH18316.1 - 8.4 7.0 15.9 0.27 11.7 2.8 3.2 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) THOC2_N PF16134.5 CEH18317.1 - 2.1e-140 469.4 0.0 5.4e-140 468.0 0.0 1.7 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 CEH18317.1 - 6.1e-88 294.9 0.0 1.4e-87 293.7 0.0 1.6 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 CEH18317.1 - 1.5e-30 105.1 0.1 3.4e-30 103.9 0.1 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Vac14_Fig4_bd PF11916.8 CEH18317.1 - 0.16 11.6 0.1 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding GFO_IDH_MocA PF01408.22 CEH18318.1 - 1.5e-18 67.8 0.2 2.2e-18 67.2 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 CEH18318.1 - 0.01 16.5 0.1 0.019 15.6 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ASH PF15780.5 CEH18318.1 - 0.15 12.3 0.1 0.37 11.0 0.1 1.7 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SNARE PF05739.19 CEH18319.1 - 6.9e-15 54.8 0.2 1.4e-14 53.8 0.2 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CEH18319.1 - 6.5e-07 29.2 3.3 0.00043 20.0 0.3 2.2 2 0 0 2 2 2 2 Syntaxin Syntaxin-18_N PF10496.9 CEH18319.1 - 0.00055 20.1 1.9 0.00085 19.5 0.1 2.1 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DUF1664 PF07889.12 CEH18319.1 - 0.018 15.1 0.6 0.85 9.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 CEH18319.1 - 0.033 14.7 2.2 0.049 14.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF3130 PF11328.8 CEH18319.1 - 0.053 13.8 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 Glyco_tranf_2_3 PF13641.6 CEH18320.1 - 1.5e-33 116.6 0.1 1.1e-20 74.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CEH18320.1 - 1.6e-09 37.5 0.1 0.00029 20.4 0.0 3.0 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CEH18320.1 - 6.1e-09 35.9 0.0 8.9e-07 28.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 2 HSBP1 PF06825.12 CEH18321.1 - 4.1e-14 52.1 0.2 5.9e-14 51.6 0.2 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 TRCF PF03461.15 CEH18321.1 - 0.0076 16.6 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 TRCF domain DUF3375 PF11855.8 CEH18321.1 - 0.055 12.4 0.3 0.076 11.9 0.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3375) Apolipoprotein PF01442.18 CEH18321.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CLZ PF16526.5 CEH18321.1 - 0.068 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LZ_Tnp_IS66 PF13007.7 CEH18321.1 - 0.66 10.8 0.1 0.66 10.8 0.1 2.2 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain CCDC53 PF10152.9 CEH18321.1 - 8.3 6.8 6.1 6.3 7.2 0.0 2.2 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex K_oxygenase PF13434.6 CEH18322.1 - 1.6e-63 214.9 0.0 2e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CEH18322.1 - 0.0047 16.2 0.0 0.12 11.6 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEH18322.1 - 0.1 11.8 0.0 0.98 8.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEH18322.1 - 0.16 12.5 0.0 0.75 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ras PF00071.22 CEH18324.1 - 1.9e-65 219.4 4.6 1.5e-50 171.0 1.5 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 CEH18324.1 - 1.6e-41 141.3 0.8 1.2e-26 93.3 0.2 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH18324.1 - 8.2e-14 51.4 1.9 4.3e-10 39.3 0.6 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEH18324.1 - 2e-08 34.0 0.2 3.2e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEH18324.1 - 1.3e-05 25.1 0.0 0.0077 16.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CEH18324.1 - 0.00026 21.0 0.1 0.00089 19.3 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CEH18324.1 - 0.0018 17.7 0.3 0.34 10.3 0.1 2.3 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEH18324.1 - 0.0037 16.7 0.7 0.023 14.1 0.7 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CEH18324.1 - 0.017 14.7 0.2 0.82 9.2 0.1 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 CEH18324.1 - 0.041 14.1 0.0 9.6 6.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CEH18324.1 - 0.057 12.8 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein TetR_C_16 PF17920.1 CEH18324.1 - 0.087 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain BOP1NT PF08145.12 CEH18325.1 - 3.5e-102 341.8 5.6 5.4e-102 341.2 5.6 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CEH18325.1 - 5.8e-22 77.6 3.9 2.5e-07 31.3 0.0 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH18325.1 - 6.2e-07 29.6 0.1 0.017 15.4 0.0 4.6 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PHD20L1_u1 PF16660.5 CEH18325.1 - 0.2 12.4 1.0 0.72 10.6 1.0 1.9 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 TEX19 PF15553.6 CEH18325.1 - 0.46 10.4 8.6 6.2 6.8 6.3 2.7 2 0 0 2 2 2 0 Testis-expressed protein 19 Actin PF00022.19 CEH18326.1 - 2.7e-26 92.1 0.0 4.5e-21 74.9 0.0 4.0 3 1 0 3 3 3 3 Actin PilN PF05137.13 CEH18326.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) Aldedh PF00171.22 CEH18328.1 - 6.4e-72 242.5 0.0 7.8e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Seryl_tRNA_N PF02403.22 CEH18329.1 - 0.011 16.0 1.8 0.022 15.0 0.2 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3818 PF12825.7 CEH18329.1 - 0.15 11.1 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) OmpH PF03938.14 CEH18329.1 - 1.4 9.2 9.6 4.2 7.7 9.4 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Aminotran_1_2 PF00155.21 CEH18330.1 - 1.2e-42 146.4 0.1 1.9e-42 145.7 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CEH18330.1 - 2.1e-06 26.9 0.0 3.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CEH18330.1 - 3.5e-05 22.5 0.0 5.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CEH18330.1 - 0.0011 18.3 0.2 0.002 17.5 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CEH18330.1 - 0.003 16.9 0.3 0.005 16.2 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Preseq_ALAS PF09029.10 CEH18330.1 - 9.9 6.7 7.5 4.2 7.9 2.9 2.4 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence TEA PF01285.18 CEH18333.1 - 4.3e-29 100.4 0.1 9.1e-29 99.3 0.1 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Pyridoxal_deC PF00282.19 CEH18334.1 - 1e-19 70.5 0.2 1.6e-13 50.2 0.1 2.6 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 CEH18334.1 - 0.00053 19.3 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CEH18334.1 - 0.0012 18.1 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SHMT PF00464.19 CEH18334.1 - 0.011 14.3 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase SepSecS PF05889.13 CEH18334.1 - 0.022 13.5 0.0 0.56 8.8 0.0 2.4 2 1 1 3 3 3 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Peptidase_S10 PF00450.22 CEH18335.1 - 1.2e-88 298.3 0.2 1.6e-88 298.0 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Ndc1_Nup PF09531.10 CEH18337.1 - 9e-41 140.3 17.3 4.2e-40 138.0 17.3 1.9 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup COesterase PF00135.28 CEH18338.1 - 1.4e-74 251.9 2.8 7.5e-65 219.7 0.8 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CEH18338.1 - 1.9e-05 24.6 0.2 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chorion_2 PF03964.15 CEH18338.1 - 0.047 14.5 1.2 0.1 13.5 0.2 2.0 1 1 1 2 2 2 0 Chorion family 2 Y_phosphatase2 PF03162.13 CEH18339.1 - 2.3e-55 186.7 0.1 3.2e-55 186.2 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CEH18339.1 - 9.7e-07 29.0 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEH18339.1 - 0.00092 18.8 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CEH18339.1 - 0.0041 16.9 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain FXMR_C2 PF16098.5 CEH18339.1 - 0.14 12.6 0.2 3.9 8.0 0.1 2.6 1 1 1 2 2 2 0 Fragile X-related mental retardation protein C-terminal region 2 MmgE_PrpD PF03972.14 CEH18340.1 - 1.7e-137 458.6 0.1 2.1e-137 458.3 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RabGAP-TBC PF00566.18 CEH18341.1 - 3.4e-21 75.9 1.2 2.3e-16 60.1 0.3 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GMP_synt_C PF00958.22 CEH18342.1 - 1.6e-42 143.5 0.0 3.1e-42 142.5 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CEH18342.1 - 3.8e-38 131.2 0.0 8.3e-38 130.1 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CEH18342.1 - 5.3e-11 42.1 0.2 2.6e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CEH18342.1 - 2.5e-09 37.2 0.0 5.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 CEH18342.1 - 0.00049 19.0 0.4 0.00092 18.1 0.2 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 CEH18342.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 CEH18342.1 - 0.003 17.1 0.0 0.09 12.3 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 CEH18342.1 - 0.017 14.4 0.1 0.031 13.6 0.1 1.4 1 0 0 1 1 1 0 Arginosuccinate synthase sCache_like PF16736.5 CEH18342.1 - 0.15 12.1 0.2 0.27 11.3 0.2 1.4 1 0 0 1 1 1 0 Single Cache-like HOASN PF14515.6 CEH18342.1 - 0.16 12.4 0.1 0.35 11.3 0.1 1.5 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices PCNA_N PF00705.18 CEH18343.1 - 5.6e-51 171.5 1.8 1.1e-50 170.6 1.8 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CEH18343.1 - 1.1e-40 138.7 0.2 3.2e-19 69.4 0.0 3.2 3 1 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CEH18343.1 - 0.0059 16.1 0.0 0.022 14.2 0.0 2.0 2 1 0 2 2 2 1 Rad9 ICMT PF04140.14 CEH18344.1 - 1.2e-14 54.4 0.3 1.3e-13 51.2 0.3 2.2 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CEH18344.1 - 2.2e-10 40.9 0.8 4.5e-10 39.9 0.8 1.6 1 1 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 CEH18344.1 - 0.054 13.0 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Zn_clus PF00172.18 CEH18346.1 - 0.00065 19.8 9.1 0.00065 19.8 9.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CASP_C PF08172.12 CEH18347.1 - 6.6e-58 196.0 4.3 6.6e-58 196.0 4.3 3.9 2 1 1 3 3 3 1 CASP C terminal Nif11 PF07862.11 CEH18347.1 - 0.027 14.8 0.3 0.027 14.8 0.3 3.4 3 0 0 3 3 3 0 Nif11 domain CENP-H PF05837.12 CEH18347.1 - 0.093 13.1 0.3 0.093 13.1 0.3 6.5 4 1 3 7 7 7 0 Centromere protein H (CENP-H) DUF5624 PF18538.1 CEH18347.1 - 2.3 8.3 5.4 34 4.6 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5624) Baculo_F PF12259.8 CEH18347.1 - 3.6 6.0 5.5 39 2.6 5.3 2.3 1 1 0 1 1 1 0 Baculovirus F protein ATG7_N PF16420.5 CEH18348.1 - 1.2e-82 278.0 0.0 1.4e-82 277.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CEH18348.1 - 5e-45 153.8 0.0 9.1e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CEH18348.1 - 0.043 13.9 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CEH18348.1 - 0.19 11.1 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zinc_ribbon_10 PF10058.9 CEH18349.1 - 3.5e-17 61.8 0.7 5.6e-17 61.2 0.7 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Mu-like_Com PF10122.9 CEH18349.1 - 0.0031 16.9 0.3 0.0066 15.9 0.3 1.5 1 0 0 1 1 1 1 Mu-like prophage protein Com COG5 PF10392.9 CEH18349.1 - 0.22 11.7 0.2 0.39 10.9 0.2 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 zf-RanBP PF00641.18 CEH18349.1 - 0.97 8.8 3.6 1.9 7.9 0.2 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others TF_Zn_Ribbon PF08271.12 CEH18349.1 - 2.3 7.8 4.1 8.4 6.0 4.3 1.8 1 1 1 2 2 2 0 TFIIB zinc-binding ATP11 PF06644.11 CEH18350.1 - 2.6e-74 250.4 0.6 4.2e-74 249.8 0.6 1.3 1 0 0 1 1 1 1 ATP11 protein DUF4603 PF15376.6 CEH18350.1 - 0.095 10.1 9.2 0.13 9.6 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Rab5ip PF07019.12 CEH18351.1 - 8.6e-11 42.3 6.2 1.2e-10 41.8 6.2 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DAGK_cat PF00781.24 CEH18352.1 - 3.4e-24 84.9 0.1 6.5e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SNARE_assoc PF09335.11 CEH18353.1 - 3.7e-14 53.3 5.8 9.6e-14 51.9 5.8 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein Mob1_phocein PF03637.17 CEH18355.1 - 2.8e-77 258.5 0.0 3.3e-77 258.3 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Acetyltransf_1 PF00583.25 CEH18356.1 - 4.4e-05 23.7 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEH18356.1 - 0.0045 17.4 0.0 0.0082 16.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEH18356.1 - 0.0076 16.2 0.2 0.037 14.0 0.1 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain PRR18 PF15671.5 CEH18357.1 - 0.23 11.3 8.7 0.37 10.6 8.7 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 VPS9 PF02204.18 CEH18358.1 - 2.5e-13 50.1 0.0 5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Peptidase_S10 PF00450.22 CEH18359.1 - 2.4e-103 346.8 0.1 3.6e-103 346.2 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Apolipoprotein PF01442.18 CEH18359.1 - 0.063 13.1 1.1 0.1 12.5 1.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phosducin PF02114.16 CEH18360.1 - 1.2e-14 54.0 0.1 3.2e-09 36.1 0.0 3.3 3 0 0 3 3 3 3 Phosducin zf-C3HC4 PF00097.25 CEH18361.1 - 7.1e-09 35.4 1.6 7.1e-09 35.4 1.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEH18361.1 - 7.1e-08 32.3 3.0 7.1e-08 32.3 3.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEH18361.1 - 1.4e-07 31.2 5.1 6e-07 29.2 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEH18361.1 - 1.6e-07 31.5 4.6 5.1e-06 26.7 2.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 CEH18361.1 - 1.3e-05 25.3 3.4 1.3e-05 25.3 3.4 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CEH18361.1 - 3.5e-05 23.6 4.1 4.5e-05 23.2 0.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH18361.1 - 7.8e-05 22.6 1.3 7.8e-05 22.6 1.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CEH18361.1 - 0.083 13.2 0.3 0.083 13.2 0.3 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-Nse PF11789.8 CEH18361.1 - 0.085 12.7 0.6 0.2 11.5 0.6 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CEH18361.1 - 0.43 10.5 7.8 0.62 10.0 3.7 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CEH18361.1 - 0.93 9.3 7.0 0.92 9.3 4.3 2.2 2 0 0 2 2 2 0 RING-like zinc finger Methyltransf_3 PF01596.17 CEH18362.1 - 0.22 10.7 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase Fe-S_biosyn PF01521.20 CEH18363.1 - 7.3e-09 35.8 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PEHE PF15275.6 CEH18364.1 - 0.0002 22.0 2.6 0.0002 22.0 2.6 4.2 4 1 0 4 4 4 1 PEHE domain SAS4 PF15460.6 CEH18364.1 - 0.00033 20.7 4.3 0.00069 19.7 4.3 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 TPR_2 PF07719.17 CEH18365.1 - 5.7e-21 72.9 51.4 4.9e-05 23.1 0.6 16.9 17 1 0 17 17 16 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEH18365.1 - 1.5e-17 64.0 104.3 3.6e-07 30.7 6.6 16.1 11 5 5 16 16 16 5 Tetratricopeptide repeat TPR_8 PF13181.6 CEH18365.1 - 1.6e-15 55.9 28.5 0.0061 16.7 0.2 13.7 14 1 0 14 14 13 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEH18365.1 - 1.6e-15 57.3 66.0 0.00013 22.4 0.0 13.5 11 3 4 15 15 14 7 Tetratricopeptide repeat TPR_1 PF00515.28 CEH18365.1 - 2.3e-15 55.7 35.4 2.8e-05 23.7 0.1 13.7 15 1 0 15 15 15 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEH18365.1 - 6.8e-14 51.2 12.6 0.0065 16.8 0.1 12.2 12 1 1 13 13 12 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEH18365.1 - 1.8e-13 50.1 93.4 6.1e-07 29.7 0.5 19.1 13 5 6 19 19 18 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEH18365.1 - 2.3e-11 43.2 31.5 0.00057 19.5 0.0 13.0 15 1 1 16 16 16 3 TPR repeat TPR_9 PF13371.6 CEH18365.1 - 4.2e-06 26.8 0.7 4.2e-06 26.8 0.7 10.1 11 1 0 11 11 10 3 Tetratricopeptide repeat ChAPs PF09295.10 CEH18365.1 - 0.00016 20.8 0.8 0.82 8.6 0.1 3.5 3 1 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 CEH18365.1 - 0.00097 19.6 0.6 0.00097 19.6 0.6 8.0 8 1 1 9 9 9 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 CEH18365.1 - 0.0013 19.0 18.7 0.041 14.1 0.2 6.8 7 0 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 CEH18365.1 - 0.01 14.8 7.9 0.22 10.4 1.8 3.5 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 CEH18365.1 - 0.011 16.1 73.4 0.086 13.1 1.9 12.6 10 4 3 13 13 13 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEH18365.1 - 0.049 13.7 0.9 15 5.8 0.0 4.9 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 CEH18365.1 - 0.21 11.7 28.4 1.8 8.8 0.3 10.0 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEH18365.1 - 2.6 8.8 32.6 70 4.4 0.0 11.8 14 0 0 14 14 11 0 Tetratricopeptide repeat tRNA-synt_2c PF01411.19 CEH18366.1 - 4.3e-212 705.5 0.0 5.5e-212 705.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CEH18366.1 - 2.4e-14 53.2 0.4 4.8e-14 52.2 0.4 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CEH18366.1 - 3.2e-06 27.6 8.9 1.5e-05 25.4 8.9 2.2 1 1 0 1 1 1 1 DHHA1 domain SpoVS PF04232.12 CEH18367.1 - 0.078 12.7 0.4 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Stage V sporulation protein S (SpoVS) TPR_1 PF00515.28 CEH18369.1 - 1.1e-20 72.5 0.1 3.1e-05 23.6 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEH18369.1 - 2e-14 52.5 6.8 0.00021 21.2 0.1 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEH18369.1 - 2.8e-13 49.3 1.8 0.00096 18.8 0.0 5.1 4 1 1 5 5 5 3 TPR repeat TPR_8 PF13181.6 CEH18369.1 - 4.5e-11 42.0 0.2 0.0063 16.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEH18369.1 - 2.1e-10 40.3 7.7 0.002 18.4 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEH18369.1 - 3.3e-10 39.9 17.6 0.0016 19.1 0.0 6.4 7 1 1 8 8 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEH18369.1 - 8.3e-08 31.7 7.3 0.017 15.1 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEH18369.1 - 8.7e-08 32.2 4.2 0.0017 18.4 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEH18369.1 - 1e-07 32.5 9.0 0.0018 18.9 0.2 6.0 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEH18369.1 - 3.2e-07 30.5 4.7 6.2e-06 26.4 0.2 4.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEH18369.1 - 8.8e-06 26.1 10.0 0.042 14.4 0.0 5.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 CEH18369.1 - 0.00011 21.9 0.6 0.0046 16.8 0.4 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH18369.1 - 0.026 14.7 5.0 0.097 12.9 0.5 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 CEH18369.1 - 0.044 13.8 0.1 15 5.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 CEH18369.1 - 0.14 12.5 12.2 0.4 11.0 1.5 5.0 3 2 1 5 5 5 0 Tetratricopeptide repeat Raftlin PF15250.6 CEH18369.1 - 5 5.8 5.9 4.9 5.8 4.0 1.8 2 0 0 2 2 2 0 Raftlin adh_short_C2 PF13561.6 CEH18370.1 - 4.8e-54 183.4 1.3 6.1e-54 183.0 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH18370.1 - 3.8e-44 150.5 3.1 5.1e-44 150.1 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH18370.1 - 2.3e-19 70.0 0.7 3.1e-19 69.6 0.7 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CEH18370.1 - 0.00054 19.5 0.2 0.001 18.6 0.2 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEH18370.1 - 0.018 14.5 0.8 0.034 13.6 0.8 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CoA_binding PF02629.19 CEH18370.1 - 0.062 14.0 2.0 0.16 12.7 0.1 2.3 2 1 0 2 2 2 0 CoA binding domain YAcAr PF10686.9 CEH18370.1 - 0.58 10.1 5.1 2.4 8.2 0.6 3.7 2 2 2 4 4 4 0 YspA, cpYpsA-related SLOG family DUF1772 PF08592.11 CEH18371.1 - 0.012 16.0 0.0 0.028 14.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) PAP_central PF04928.17 CEH18376.1 - 6.7e-110 365.9 0.0 8.7e-110 365.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CEH18376.1 - 3.1e-51 173.4 0.0 5.2e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CEH18376.1 - 1.2e-10 41.5 0.0 4.7e-10 39.6 0.0 2.0 1 1 1 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 CEH18376.1 - 0.0088 15.8 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain Ccdc124 PF06244.12 CEH18377.1 - 9.2e-25 87.7 15.2 2.9e-24 86.0 15.2 1.9 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF4829 PF16111.5 CEH18377.1 - 0.11 13.3 1.6 0.14 13.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4829) DUF2852 PF11014.8 CEH18377.1 - 3.5 7.8 6.1 0.28 11.3 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) TspO_MBR PF03073.15 CEH18378.1 - 3e-37 127.7 11.7 3.5e-37 127.5 11.7 1.0 1 0 0 1 1 1 1 TspO/MBR family bZIP_1 PF00170.21 CEH18379.1 - 2.4e-06 27.5 3.9 5.1e-06 26.5 3.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CEH18379.1 - 6.8e-06 26.1 4.9 1.2e-05 25.2 4.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper MRJP PF03022.16 CEH18380.1 - 1e-29 103.8 0.0 1.8e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Major royal jelly protein Phytase-like PF13449.6 CEH18380.1 - 0.0005 20.1 0.0 0.023 14.6 0.0 2.2 1 1 0 1 1 1 1 Esterase-like activity of phytase PD40 PF07676.12 CEH18380.1 - 0.0017 18.2 0.1 0.0057 16.6 0.0 2.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 CEH18380.1 - 0.0034 17.0 0.2 0.016 14.8 0.1 2.0 2 1 0 2 2 2 1 PQQ-like domain Reg_prop PF07494.11 CEH18380.1 - 0.14 12.5 0.0 0.75 10.2 0.0 2.3 1 0 0 1 1 1 0 Two component regulator propeller GWT1 PF06423.12 CEH18382.1 - 0.015 15.4 0.5 0.026 14.7 0.5 1.4 1 0 0 1 1 1 0 GWT1 Cation_ATPase_C PF00689.21 CEH18382.1 - 1.5 8.5 5.3 0.32 10.7 1.8 1.5 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF1682 PF07946.14 CEH18383.1 - 6.2e-71 239.2 0.0 7.2e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Peptidase_S49_N PF08496.10 CEH18383.1 - 8 6.5 11.1 17 5.5 9.5 2.4 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Nucleoporin_C PF03177.14 CEH18384.1 - 1.1e-87 295.2 3.7 1.3e-87 295.0 3.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 CEH18384.1 - 3.5e-17 62.3 0.0 5e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Ribosomal_S11 PF00411.19 CEH18387.1 - 0.1 13.0 2.9 0.21 12.0 2.9 1.4 1 0 0 1 1 1 0 Ribosomal protein S11 NICE-1 PF15845.5 CEH18389.1 - 0.27 12.0 2.0 0.48 11.2 2.0 1.3 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family VIR_N PF15912.5 CEH18389.1 - 2.8 7.5 21.4 4 7.0 21.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Asp-B-Hydro_N PF05279.11 CEH18389.1 - 9.7 6.2 38.7 13 5.7 38.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Metallophos PF00149.28 CEH18390.1 - 9.6e-37 127.5 0.8 1.4e-36 126.9 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEH18390.1 - 1.3e-05 25.5 0.1 2.5e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 CEH18390.1 - 0.061 12.9 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain RCC1 PF00415.18 CEH18392.1 - 2.8e-18 66.2 4.0 0.00045 20.8 0.0 5.7 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEH18392.1 - 5.7e-10 38.7 6.6 2.6e-07 30.2 0.1 4.8 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CEH18392.1 - 1.5e-06 28.4 0.0 2.5e-05 24.5 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain Ank_4 PF13637.6 CEH18392.1 - 1e-05 26.0 0.3 0.00012 22.6 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEH18392.1 - 0.017 15.6 0.0 0.073 13.7 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.30 CEH18392.1 - 0.02 15.3 0.1 0.062 13.8 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 CEH18392.1 - 0.028 15.0 0.0 0.069 13.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF4646 PF15496.6 CEH18394.1 - 4.3e-21 75.8 0.0 7.7e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Med19 PF10278.9 CEH18394.1 - 5.7 6.8 10.0 1.3 8.9 6.9 1.5 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 V-ATPase_G PF03179.15 CEH18395.1 - 0.21 12.1 7.0 0.37 11.4 7.0 1.5 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Neur_chan_memb PF02932.16 CEH18395.1 - 1.1 9.3 3.4 1.5 8.8 3.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GCD14 PF08704.10 CEH18396.1 - 1e-45 156.3 0.2 6.6e-26 91.5 0.1 2.1 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 CEH18396.1 - 0.045 13.5 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SF3b10 PF07189.11 CEH18397.1 - 1.5e-31 108.3 0.0 1.8e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) RhoGEF PF00621.20 CEH18399.1 - 1.9e-12 47.8 0.0 7e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain DUF1765 PF08578.10 CEH18400.1 - 7.3e-27 94.3 4.5 1.3e-26 93.5 4.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) TFIIA PF03153.13 CEH18401.1 - 0.5 10.3 15.9 0.69 9.8 15.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GARP PF16731.5 CEH18401.1 - 4.4 6.9 41.1 1.4 8.6 26.6 2.4 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Arrestin_C PF02752.22 CEH18402.1 - 2.2e-18 67.0 0.0 1.4e-17 64.4 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEH18402.1 - 0.0011 19.0 0.0 0.021 14.9 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Seipin PF06775.14 CEH18404.1 - 4.9e-44 150.8 0.0 6.7e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Rrn6 PF10214.9 CEH18404.1 - 6 5.2 14.0 13 4.2 14.0 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3425 PF11905.8 CEH18405.1 - 5.7e-18 65.1 0.2 1.3e-17 63.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Pkinase PF00069.25 CEH18406.1 - 3.7e-59 200.2 0.0 4.6e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH18406.1 - 3.8e-36 124.7 0.0 5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH18406.1 - 1.7e-06 27.6 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEH18406.1 - 0.0021 18.0 0.0 0.13 12.2 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEH18406.1 - 0.0076 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEH18406.1 - 0.027 13.4 0.1 0.054 12.4 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain zf-CCCH PF00642.24 CEH18407.1 - 7.4e-13 48.1 16.6 2.4e-06 27.3 3.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEH18407.1 - 0.0029 17.6 10.9 0.0078 16.2 3.3 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 CEH18407.1 - 0.034 14.4 6.9 0.037 14.2 1.4 2.3 2 0 0 2 2 2 0 Zinc-finger containing family RRM_1 PF00076.22 CEH18407.1 - 0.073 12.9 0.0 1.2 9.0 0.0 2.3 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 CEH18407.1 - 0.58 10.9 4.5 0.55 11.0 0.2 2.5 2 0 0 2 2 2 0 Torus domain RasGAP PF00616.19 CEH18408.1 - 9.6e-21 74.4 0.0 1.6e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CcmD PF04995.14 CEH18409.1 - 0.032 14.3 0.8 0.059 13.5 0.8 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FeoB_associated PF12669.7 CEH18409.1 - 0.073 13.5 1.7 0.14 12.5 1.7 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SKG6 PF08693.10 CEH18409.1 - 0.17 11.3 3.7 0.35 10.3 3.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 CEH18409.1 - 0.21 12.5 0.9 0.88 10.5 0.9 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UQ_con PF00179.26 CEH18413.1 - 9.3e-23 80.4 0.0 1.4e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Transferase PF02458.15 CEH18414.1 - 1.4e-29 103.1 0.0 8.9e-29 100.4 0.0 1.8 1 1 0 1 1 1 1 Transferase family Condensation PF00668.20 CEH18414.1 - 1.6e-06 27.1 0.0 2.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Condensation domain MULE PF10551.9 CEH18417.1 - 6.3e-16 58.6 0.1 1.5e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain Fungal_trans PF04082.18 CEH18420.1 - 4.4e-26 91.5 0.1 7e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CEH18420.1 - 5.4e-09 36.0 8.1 0.00035 20.9 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEH18420.1 - 5.4e-06 26.8 5.5 0.0053 17.5 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Exo_endo_phos PF03372.23 CEH18421.1 - 6.7e-11 42.1 0.0 1.4e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Amidase PF01425.21 CEH18423.1 - 1.4e-79 268.2 0.0 3.3e-78 263.7 0.0 2.0 1 1 0 1 1 1 1 Amidase Sec7 PF01369.20 CEH18424.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 1 1 2 2 2 0 Sec7 domain DRMBL PF07522.14 CEH18426.1 - 6.3e-30 103.6 0.0 1.1e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CEH18426.1 - 0.1 12.1 0.1 0.59 9.6 0.0 2.1 1 1 1 2 2 2 0 Beta-lactamase superfamily domain FAM176 PF14851.6 CEH18427.1 - 0.094 12.4 4.7 0.14 11.8 4.7 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 CEH18427.1 - 2.6 6.2 10.7 2.6 6.2 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CEH18427.1 - 3.9 7.2 9.6 4 7.2 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DEAD PF00270.29 CEH18428.1 - 7.3e-35 120.3 0.0 1.3e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH18428.1 - 5.5e-28 97.5 0.0 1.6e-26 92.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH18428.1 - 0.0012 18.8 0.0 0.02 14.9 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEH18428.1 - 0.029 14.6 0.0 1.5 9.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain SSI PF00720.17 CEH18428.1 - 0.46 10.5 4.2 4 7.5 0.9 2.4 1 1 1 2 2 2 0 Subtilisin inhibitor-like NUDIX PF00293.28 CEH18429.1 - 5.3e-15 55.6 0.0 1.1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 CEH18429.1 - 2.4e-13 50.6 0.1 7.4e-13 49.0 0.1 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain JAB PF01398.21 CEH18430.1 - 1.2e-42 144.6 0.6 1.3e-27 96.1 0.0 2.4 1 1 1 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CEH18430.1 - 7.3e-15 55.4 0.3 1.2e-14 54.7 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CEH18430.1 - 7.2e-09 35.4 0.0 3.3e-05 23.6 0.0 2.4 1 1 1 2 2 2 2 Prokaryotic homologs of the JAB domain KH_6 PF15985.5 CEH18431.1 - 1.6e-09 37.9 0.0 3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 CEH18431.1 - 0.0021 17.9 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain GDI PF00996.18 CEH18433.1 - 1e-35 123.2 0.0 1.6e-19 69.8 0.0 2.2 1 1 1 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CEH18433.1 - 0.00037 20.7 0.1 0.00076 19.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pkinase PF00069.25 CEH18435.1 - 4.8e-70 235.9 0.0 6e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH18435.1 - 3.9e-36 124.7 0.0 5.1e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH18435.1 - 2.1e-08 33.9 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEH18435.1 - 2.2e-05 23.9 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEH18435.1 - 7.3e-05 21.7 1.1 0.00013 20.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEH18435.1 - 0.00046 20.2 0.0 0.00085 19.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CEH18435.1 - 0.004 16.7 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 CEH18435.1 - 0.035 13.1 0.1 0.035 13.1 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain PRKCSH PF07915.13 CEH18436.1 - 7.9e-16 58.8 0.0 5.3e-15 56.2 0.0 2.3 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 CEH18436.1 - 0.055 13.2 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein DUF2237 PF09996.9 CEH18437.1 - 1.4e-41 141.1 0.0 1.7e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Nic96 PF04097.14 CEH18438.1 - 6.4e-142 474.1 0.0 8.5e-75 252.4 0.1 2.1 1 1 1 2 2 2 2 Nup93/Nic96 GHMP_kinases_N PF00288.26 CEH18439.1 - 4.9e-12 45.9 0.8 1.7e-11 44.2 0.8 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CEH18439.1 - 2.9e-05 24.3 0.1 8.7e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal PilJ PF13675.6 CEH18439.1 - 0.11 12.5 0.4 0.43 10.6 0.1 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_11 PF13414.6 CEH18440.1 - 8.3e-12 44.6 2.8 0.021 14.5 0.5 4.9 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.17 CEH18440.1 - 3.3e-10 39.3 24.3 0.073 13.2 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 CEH18440.1 - 1.7e-09 37.1 13.0 0.15 11.9 0.1 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEH18440.1 - 3.8e-09 36.6 35.8 0.0053 17.5 0.5 8.1 5 1 4 9 9 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 CEH18440.1 - 2.6e-08 34.2 16.0 0.042 14.4 0.1 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEH18440.1 - 5.5e-06 26.9 30.4 0.05 14.3 6.1 6.5 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEH18440.1 - 1.3e-05 25.2 13.1 0.093 13.2 0.0 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH18440.1 - 4e-05 23.8 10.5 0.031 14.5 0.1 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CEH18440.1 - 0.00042 20.3 10.8 0.36 11.2 0.4 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEH18440.1 - 0.004 17.4 26.0 0.28 11.5 0.4 6.6 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 CEH18440.1 - 0.27 12.0 8.8 5.8 7.9 0.0 5.9 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEH18440.1 - 0.4 11.4 7.1 9.6 7.1 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEH18440.1 - 1.4 9.2 13.5 1.1e+02 3.2 0.2 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEH18440.1 - 1.5 9.0 12.4 2.5 8.3 0.5 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEH18440.1 - 6 6.9 10.4 16 5.6 0.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Inv-AAD PF18785.1 CEH18441.1 - 6.1e-26 90.8 0.2 1.4e-19 70.2 0.0 2.2 1 1 1 2 2 2 2 Invertebrate-AID/APOBEC-deaminase PAP2 PF01569.21 CEH18441.1 - 7.6e-08 32.2 8.4 2.3e-07 30.6 8.4 1.8 1 1 0 1 1 1 1 PAP2 superfamily dCMP_cyt_deam_1 PF00383.23 CEH18441.1 - 5.4e-07 29.4 0.1 1.4e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 CEH18441.1 - 0.00078 19.4 0.0 0.0044 16.9 0.0 2.0 1 1 0 1 1 1 1 APOBEC-like N-terminal domain MgtC PF02308.16 CEH18441.1 - 0.23 11.8 1.2 0.47 10.8 1.2 1.5 1 0 0 1 1 1 0 MgtC family UbiA PF01040.18 CEH18441.1 - 0.28 10.4 7.7 0.014 14.7 2.4 1.5 2 0 0 2 2 2 0 UbiA prenyltransferase family GTP_CH_N PF12471.8 CEH18442.1 - 1.8e-83 279.0 0.0 2.6e-83 278.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 CEH18442.1 - 4.7e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 2 0 0 2 2 2 1 GTP cyclohydrolase II EF-hand_1 PF00036.32 CEH18443.1 - 9.4e-21 71.8 0.3 1.4e-05 24.3 0.0 4.5 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CEH18443.1 - 1.7e-19 68.0 0.2 6.8e-05 22.5 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CEH18443.1 - 5.5e-18 65.2 0.0 2.1e-08 34.5 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CEH18443.1 - 5.2e-15 54.2 0.3 0.0026 17.2 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CEH18443.1 - 4.7e-13 48.8 0.2 9.3e-08 31.8 0.0 3.9 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 CEH18443.1 - 0.016 15.5 0.0 32 4.9 0.0 3.8 3 2 0 3 3 3 0 EF-hand domain Vps39_2 PF10367.9 CEH18444.1 - 5.5e-23 81.5 0.0 1.4e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 CEH18444.1 - 0.00017 21.8 0.4 0.009 16.3 0.0 3.1 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 CEH18444.1 - 0.002 18.0 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Region in Clathrin and VPS MAP70 PF07058.11 CEH18444.1 - 0.027 13.2 0.0 0.05 12.3 0.0 1.3 1 0 0 1 1 1 0 Microtubule-associated protein 70 TPR_8 PF13181.6 CEH18444.1 - 0.043 14.1 0.5 1.6 9.1 0.3 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEH18444.1 - 0.049 13.5 0.4 3.9 7.4 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 CEH18444.1 - 0.052 13.8 1.2 0.12 12.6 0.3 2.0 2 0 0 2 2 2 0 Tetratrico peptide repeat LINES_N PF14694.6 CEH18444.1 - 0.063 12.7 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Lines N-terminus TPR_12 PF13424.6 CEH18444.1 - 1.4 9.3 6.1 42 4.5 0.2 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat PAP1 PF08601.10 CEH18446.1 - 0.0053 16.6 0.5 0.0053 16.6 0.5 1.8 2 0 0 2 2 2 1 Transcription factor PAP1 Acetyltransf_1 PF00583.25 CEH18447.1 - 1.8e-11 44.3 0.0 2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEH18447.1 - 7e-10 38.9 0.0 8.1e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEH18447.1 - 3.1e-09 37.1 0.0 3.6e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEH18447.1 - 0.0037 17.2 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CEH18447.1 - 0.054 13.6 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pro_isomerase PF00160.21 CEH18448.1 - 2.4e-36 125.4 0.2 5.1e-36 124.3 0.0 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Dsh_C PF12316.8 CEH18448.1 - 0.13 12.6 4.9 0.2 12.0 4.9 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal WD40 PF00400.32 CEH18449.1 - 0.0099 16.7 0.2 0.0099 16.7 0.2 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat His_Phos_2 PF00328.22 CEH18450.1 - 5.2e-24 85.3 0.0 6.4e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lipoprotein_15 PF03640.15 CEH18450.1 - 0.072 12.6 0.3 0.18 11.4 0.3 1.6 1 0 0 1 1 1 0 Secreted repeat of unknown function DUF1590 PF07629.11 CEH18450.1 - 0.16 11.8 0.9 0.43 10.4 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) DUF3510 PF12022.8 CEH18451.1 - 8.7e-17 61.7 0.0 2.7e-16 60.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 CEH18451.1 - 8.8e-13 48.5 4.7 1.2e-10 41.6 3.3 3.1 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 SelP_N PF04592.14 CEH18451.1 - 1.7 8.0 9.6 3.3 7.0 9.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region His_Phos_1 PF00300.22 CEH18453.1 - 1.5e-15 57.4 3.1 2.3e-15 56.8 3.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ADH_zinc_N PF00107.26 CEH18456.1 - 1e-15 57.9 0.0 1.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEH18456.1 - 4.5e-15 55.5 2.3 1.1e-14 54.2 2.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 CEH18456.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MR_MLE_N PF02746.16 CEH18456.1 - 0.052 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Phage_holin_3_3 PF16083.5 CEH18456.1 - 0.074 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III AlaDh_PNT_C PF01262.21 CEH18456.1 - 0.077 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RseC_MucC PF04246.12 CEH18456.1 - 0.13 12.2 1.9 0.23 11.4 1.9 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC LIP PF03583.14 CEH18458.1 - 3.3e-43 148.1 0.0 4.5e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 CEH18458.1 - 0.00057 19.2 0.5 0.037 13.3 0.5 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CEH18458.1 - 0.0079 15.7 0.8 6.3 6.2 0.0 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family FAD_binding_4 PF01565.23 CEH18459.1 - 4.7e-20 71.7 1.4 9.5e-20 70.8 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CEH18459.1 - 0.011 15.8 0.1 0.068 13.3 0.0 2.4 2 0 0 2 2 2 0 Berberine and berberine like Aldo_ket_red PF00248.21 CEH18460.1 - 3.3e-35 121.7 0.0 1.5e-33 116.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MCM PF00493.23 CEH18463.1 - 1.4e-97 325.2 0.0 2e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEH18463.1 - 2e-38 131.1 1.0 3.6e-38 130.3 1.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEH18463.1 - 3.7e-26 91.4 1.1 7.5e-26 90.4 1.1 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 CEH18463.1 - 1.3e-08 35.0 0.0 5.1e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEH18463.1 - 5.2e-08 32.5 0.1 4.8e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEH18463.1 - 5.6e-05 23.0 0.1 0.00072 19.4 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEH18463.1 - 0.0029 17.3 0.1 0.73 9.5 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_16 PF13191.6 CEH18463.1 - 0.05 14.0 1.9 0.13 12.6 0.1 2.8 2 2 0 2 2 2 0 AAA ATPase domain Cdc6_C PF09079.11 CEH18463.1 - 0.11 12.5 0.1 0.92 9.5 0.0 2.6 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain PadR PF03551.14 CEH18463.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family AAA_lid_2 PF17863.1 CEH18463.1 - 0.14 12.0 2.1 0.47 10.3 0.3 2.3 2 0 0 2 2 2 0 AAA lid domain GATase PF00117.28 CEH18464.1 - 4.8e-06 26.5 0.0 8.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I HHH_2 PF12826.7 CEH18464.1 - 0.15 12.1 0.8 17 5.6 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif ATG16 PF08614.11 CEH18465.1 - 2.3e-39 135.7 13.8 3.2e-39 135.2 13.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 CEH18465.1 - 0.019 14.5 11.7 0.03 13.9 11.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TraF PF13728.6 CEH18465.1 - 0.052 13.4 0.8 0.099 12.4 0.8 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein SH3_11 PF18103.1 CEH18465.1 - 0.14 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain ING PF12998.7 CEH18465.1 - 0.9 10.2 9.4 0.38 11.4 0.9 2.3 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding TolA_bind_tri PF16331.5 CEH18465.1 - 1.1 9.3 21.6 0.8 9.8 0.6 3.4 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF4407 PF14362.6 CEH18465.1 - 1.3 8.4 11.0 1.6 8.0 10.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin_2 PF14523.6 CEH18465.1 - 2 8.8 11.2 0.34 11.3 5.6 2.3 2 1 0 3 3 3 0 Syntaxin-like protein HIP1_clath_bdg PF16515.5 CEH18465.1 - 3.7 8.2 22.2 2.8 8.6 13.3 3.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prominin PF05478.11 CEH18465.1 - 4.4 5.1 10.6 6.1 4.7 10.6 1.1 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.10 CEH18465.1 - 7.6 6.7 10.2 4.8 7.4 7.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 CEH18465.1 - 9 6.4 7.2 9.7 6.3 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Abhydrolase_3 PF07859.13 CEH18466.1 - 1e-21 77.8 0.3 3.1e-20 72.9 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEH18466.1 - 2.5e-17 62.8 0.0 2.8e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CEH18466.1 - 0.039 13.4 0.0 0.092 12.2 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family zf-C4H2 PF10146.9 CEH18467.1 - 0.072 13.4 2.6 0.083 13.2 2.6 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein PQ-loop PF04193.14 CEH18468.1 - 4.1e-24 84.1 4.2 1.1e-11 44.3 0.1 2.7 3 0 0 3 3 3 2 PQ loop repeat SAM_PNT PF02198.16 CEH18469.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain IGR PF09597.10 CEH18469.1 - 0.21 11.7 0.5 0.64 10.2 0.5 1.9 1 0 0 1 1 1 0 IGR protein motif 2OG-FeII_Oxy_2 PF13532.6 CEH18470.1 - 1e-09 38.9 0.1 2.5e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FAM75 PF14650.6 CEH18471.1 - 0.32 10.5 1.4 0.52 9.8 1.4 1.2 1 0 0 1 1 1 0 FAM75 family BMFP PF04380.13 CEH18475.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Membrane fusogenic activity MerR-DNA-bind PF09278.11 CEH18476.1 - 0.61 10.7 14.2 0.99 10.0 4.1 3.7 3 1 0 3 3 3 0 MerR, DNA binding MPC PF03650.13 CEH18480.1 - 1.7e-35 121.5 0.0 2e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers HAD_2 PF13419.6 CEH18481.1 - 0.18 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase P34-Arc PF04045.14 CEH18482.1 - 2.7e-99 331.8 0.2 5.9e-97 324.1 0.2 2.1 1 1 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF3638 PF12340.8 CEH18482.1 - 0.051 12.9 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Ran_BP1 PF00638.18 CEH18483.1 - 1.7e-15 57.4 0.0 1.2e-07 32.0 0.0 2.2 2 0 0 2 2 2 2 RanBP1 domain WH1 PF00568.23 CEH18483.1 - 0.0068 16.3 0.0 3.6 7.6 0.0 2.4 2 1 0 2 2 2 2 WH1 domain Spore_coat_CotO PF14153.6 CEH18483.1 - 1.6 8.6 15.1 0.37 10.7 11.7 1.5 1 1 1 2 2 2 0 Spore coat protein CotO GCIP PF13324.6 CEH18483.1 - 1.8 8.1 7.4 2.9 7.4 7.4 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Macoilin PF09726.9 CEH18483.1 - 1.9 6.9 8.6 2.3 6.7 8.6 1.1 1 0 0 1 1 1 0 Macoilin family LAP1C PF05609.12 CEH18483.1 - 2 7.4 12.4 3 6.9 12.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) YL1 PF05764.13 CEH18483.1 - 5.4 7.1 20.2 7.7 6.5 20.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Apt1 PF10351.9 CEH18483.1 - 9.2 5.0 13.4 13 4.5 13.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_pol_Rpb2_6 PF00562.28 CEH18485.1 - 5.6e-65 219.9 0.0 9.4e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CEH18485.1 - 2.2e-61 206.9 0.2 3.2e-61 206.4 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CEH18485.1 - 8.9e-33 113.5 0.6 1.8e-32 112.5 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CEH18485.1 - 1e-32 112.4 0.1 2.5e-32 111.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CEH18485.1 - 7.9e-26 90.1 1.4 1.8e-25 89.0 1.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CEH18485.1 - 1.3e-20 73.3 0.8 5.8e-20 71.3 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CEH18485.1 - 1.9e-10 41.1 0.7 7.3e-10 39.3 0.7 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L13 PF00572.18 CEH18486.1 - 0.0013 19.0 0.9 0.16 12.2 0.1 2.8 1 1 0 2 2 2 1 Ribosomal protein L13 Ribosomal_L32e PF01655.18 CEH18487.1 - 1.1e-35 122.3 0.0 1.2e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_S3_C PF00189.20 CEH18488.1 - 7.3e-25 87.3 1.0 5.3e-24 84.5 0.5 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CEH18488.1 - 1.3e-12 47.3 0.0 2.3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 CEH18488.1 - 0.016 15.7 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 CEH18488.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus ubiquitin PF00240.23 CEH18489.1 - 1.4e-34 117.7 0.5 1.9e-34 117.2 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CEH18489.1 - 5.8e-30 102.9 10.9 8.8e-30 102.4 10.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CEH18489.1 - 2.8e-16 59.1 0.6 4.5e-16 58.4 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEH18489.1 - 2e-05 25.0 0.1 7.7e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CEH18489.1 - 0.0048 17.2 0.0 0.0084 16.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CEH18489.1 - 0.0049 16.8 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEH18489.1 - 0.0069 16.5 0.1 0.013 15.6 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CEH18489.1 - 0.013 15.5 1.1 4 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CEH18489.1 - 0.027 15.0 0.1 0.033 14.7 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Pex24p PF06398.11 CEH18490.1 - 5.7e-19 68.3 2.7 5.7e-19 68.3 2.7 2.5 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Opi1 PF08618.10 CEH18491.1 - 7.2e-106 354.9 2.0 9.1e-95 318.4 1.5 3.2 3 0 0 3 3 3 2 Transcription factor Opi1 REF PF05755.12 CEH18491.1 - 7.5e-06 25.9 0.6 0.075 12.8 0.0 2.8 3 0 0 3 3 3 2 Rubber elongation factor protein (REF) COX4 PF02936.14 CEH18491.1 - 0.03 14.3 1.6 0.063 13.3 1.6 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV AvrPtoB-E3_ubiq PF09046.10 CEH18491.1 - 0.12 12.6 0.0 58 4.0 0.0 3.2 3 0 0 3 3 3 0 AvrPtoB E3 ubiquitin ligase PH PF00169.29 CEH18493.1 - 0.00045 20.7 0.3 0.24 11.9 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 CEH18493.1 - 0.00083 19.7 0.0 0.08 13.3 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain CPSase_L_D2 PF02786.17 CEH18494.1 - 8.4e-83 277.0 0.2 1.4e-82 276.3 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CEH18494.1 - 2.3e-62 210.3 0.0 3.9e-62 209.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CEH18494.1 - 1.1e-38 132.2 0.1 2.3e-38 131.1 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain HMGL-like PF00682.19 CEH18494.1 - 6.1e-29 101.4 0.0 1.2e-28 100.4 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.19 CEH18494.1 - 9.5e-29 99.7 0.0 2.8e-28 98.1 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CEH18494.1 - 7.2e-17 61.0 1.0 1.6e-16 59.9 1.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CEH18494.1 - 1e-15 57.3 4.5 5.4e-08 32.5 0.3 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CEH18494.1 - 1.6e-10 40.9 0.0 3.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CEH18494.1 - 1e-07 31.7 0.1 2.2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CEH18494.1 - 1.4e-06 28.5 0.0 2.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 CEH18494.1 - 1.4e-06 28.0 0.1 6.3e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 CEH18494.1 - 7e-06 26.7 0.5 0.037 14.7 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.19 CEH18494.1 - 4.4e-05 23.3 0.0 8.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 CEH18494.1 - 0.00011 21.8 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GCV_H PF01597.19 CEH18494.1 - 0.00023 21.1 1.1 0.0042 17.0 0.3 2.9 2 1 1 3 3 3 1 Glycine cleavage H-protein RnfC_N PF13375.6 CEH18494.1 - 0.00024 21.0 0.4 0.00053 19.9 0.4 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 CEH18494.1 - 0.00079 18.7 0.3 0.013 14.7 0.1 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion NQRA PF05896.11 CEH18494.1 - 0.001 18.5 0.1 0.0022 17.5 0.1 1.5 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.9 CEH18494.1 - 0.0022 18.0 0.1 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.6 CEH18494.1 - 0.0047 16.2 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp PTS_EIIA_1 PF00358.20 CEH18494.1 - 0.15 11.8 0.1 2.5 7.9 0.1 2.8 2 1 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 CEH18494.1 - 0.19 12.0 2.7 1.4 9.2 0.1 3.3 3 1 1 4 4 2 0 Peptidase family M23 PEX11 PF05648.14 CEH18495.1 - 8.2e-16 58.1 0.0 7.3e-14 51.8 0.0 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DNA_ligase_A_M PF01068.21 CEH18496.1 - 2.8e-07 30.4 0.0 5.7e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 CEH18496.1 - 1.6e-06 28.0 0.1 3.8e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain RNA_ligase PF09414.10 CEH18496.1 - 5.1e-05 23.6 0.0 0.00016 22.0 0.0 1.8 1 1 0 1 1 1 1 RNA ligase DAGAT PF03982.13 CEH18497.1 - 4e-55 186.8 1.9 1.3e-40 139.2 0.1 2.7 1 1 1 2 2 2 2 Diacylglycerol acyltransferase Tau95 PF09734.9 CEH18499.1 - 1.3e-33 116.7 0.5 1.3e-33 116.7 0.5 3.3 4 0 0 4 4 4 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CEH18499.1 - 1.4e-16 60.8 0.0 5.9e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Tau95 Triple barrel domain AIP3 PF03915.13 CEH18500.1 - 7.7e-128 427.1 0.0 1e-127 426.6 0.0 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Syntaxin-6_N PF09177.11 CEH18500.1 - 0.036 14.6 2.9 6.3 7.4 0.0 3.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal TMF_TATA_bd PF12325.8 CEH18500.1 - 0.065 13.5 5.4 0.82 9.9 1.1 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2408 PF10303.9 CEH18500.1 - 0.098 13.2 1.2 0.24 11.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Spc7 PF08317.11 CEH18500.1 - 6.4 5.5 6.0 12 4.6 0.0 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein SPT_ssu-like PF11779.8 CEH18501.1 - 0.0045 16.6 1.3 0.0061 16.2 1.3 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like UPF0242 PF06785.11 CEH18501.1 - 0.18 11.9 0.1 0.23 11.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Flagellin_C PF00700.21 CEH18503.1 - 1.2 9.6 3.8 0.68 10.3 1.1 2.0 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF4050 PF13259.6 CEH18503.1 - 7.3 6.9 11.0 0.24 11.7 1.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Zn_clus PF00172.18 CEH18504.1 - 0.00025 21.1 8.6 0.00044 20.3 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 CEH18504.1 - 0.24 11.4 0.0 0.44 10.6 0.0 1.4 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.25 CEH18505.1 - 3.2e-35 121.8 0.0 4.2e-21 75.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH18505.1 - 8e-13 48.3 0.0 6e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF4994 PF16385.5 CEH18505.1 - 0.013 15.4 0.0 0.05 13.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function Kinase-like PF14531.6 CEH18505.1 - 0.036 13.4 0.0 0.45 9.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Acyl-CoA_dh_1 PF00441.24 CEH18511.1 - 4.1e-49 166.6 1.4 6.5e-49 166.0 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEH18511.1 - 3.8e-27 94.3 1.4 6.5e-27 93.6 0.4 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CEH18511.1 - 3.6e-23 82.4 0.7 6e-23 81.7 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CEH18511.1 - 3.2e-18 66.3 1.1 5.7e-18 65.5 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CEH18511.1 - 0.0012 18.6 0.2 0.0048 16.6 0.2 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short PF00106.25 CEH18512.1 - 1.3e-32 112.8 0.1 1.8e-32 112.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH18512.1 - 4.6e-21 75.4 0.0 6.6e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH18512.1 - 1e-07 32.0 0.1 2.3e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CEH18512.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family tRNA_bind_3 PF17176.4 CEH18514.1 - 0.13 12.6 0.0 21 5.4 0.0 2.7 3 0 0 3 3 3 0 tRNA-binding domain Pyrophosphatase PF00719.19 CEH18515.1 - 1e-64 217.2 1.0 7.6e-55 185.1 0.1 2.2 1 1 1 2 2 2 2 Inorganic pyrophosphatase SAPI PF16560.5 CEH18515.1 - 0.1 12.2 0.0 9.3 5.8 0.0 2.3 1 1 1 2 2 2 0 Putative mobile pathogenicity island Ribosomal_L6 PF00347.23 CEH18517.1 - 6.8e-14 52.3 0.0 1.3e-11 45.0 0.0 2.7 3 0 0 3 3 3 2 Ribosomal protein L6 LSM PF01423.22 CEH18518.1 - 7.6e-19 67.2 0.3 3e-18 65.3 0.3 1.7 1 1 0 1 1 1 1 LSM domain RNase_H2_suC PF08615.11 CEH18518.1 - 0.034 14.3 0.1 0.047 13.9 0.1 1.1 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) HPP PF04982.13 CEH18520.1 - 6.3e-38 129.7 10.0 6.3e-38 129.7 10.0 1.5 2 0 0 2 2 2 1 HPP family PDZ_5 PF17817.1 CEH18521.1 - 0.0028 17.9 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF3670 PF12419.8 CEH18521.1 - 0.037 13.9 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 SNF2 Helicase protein AICARFT_IMPCHas PF01808.18 CEH18522.1 - 1.7e-87 293.6 0.1 2.5e-87 293.1 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CEH18522.1 - 4.2e-21 74.9 0.0 8.9e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Porin_4 PF13609.6 CEH18524.1 - 0.074 12.8 0.1 0.074 12.8 0.1 1.1 1 0 0 1 1 1 0 Gram-negative porin Forkhead PF00250.18 CEH18525.1 - 2.4e-31 107.8 0.0 3.9e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain CDP-OH_P_transf PF01066.21 CEH18527.1 - 1.4e-14 54.6 0.0 1.4e-14 54.6 0.0 2.9 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Utp11 PF03998.13 CEH18529.1 - 2e-59 201.5 9.9 6.2e-59 199.9 9.9 1.7 1 1 0 1 1 1 1 Utp11 protein Sigma70_ner PF04546.13 CEH18529.1 - 0.057 13.3 6.7 0.88 9.4 2.6 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region REC104 PF17378.2 CEH18529.1 - 0.1 12.4 0.0 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Meiotic recombination protein REC104 DUF4798 PF16055.5 CEH18529.1 - 5 7.4 18.3 0.07 13.4 7.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4798) DPBB_1 PF03330.18 CEH18530.1 - 1.8e-06 28.1 0.0 2.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase NRDE-2 PF08424.10 CEH18531.1 - 1.8e-53 181.8 0.1 1.8e-53 181.8 0.1 3.3 4 0 0 4 4 4 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CEH18531.1 - 0.26 12.2 25.0 1.7 9.7 0.2 8.0 7 1 1 8 8 8 0 Tetratricopeptide repeat CN_hydrolase PF00795.22 CEH18532.1 - 4.3e-16 59.0 0.0 5.5e-14 52.1 0.0 3.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 CEH18533.1 - 4.9e-34 117.8 30.5 4.9e-34 117.8 30.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH18533.1 - 1.2e-08 34.3 5.6 1.2e-08 34.3 5.6 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter UL42 PF17638.2 CEH18533.1 - 0.28 11.2 0.1 0.28 11.2 0.1 2.3 3 0 0 3 3 3 0 HCMV UL42 Glyco_hydro_63 PF03200.16 CEH18534.1 - 3.5e-08 32.6 5.0 1.4e-06 27.3 0.8 4.3 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain MRP-S34 PF16053.5 CEH18536.1 - 6e-08 32.4 0.1 0.00033 20.3 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial 28S ribosomal protein S34 CDC27 PF09507.10 CEH18536.1 - 0.18 11.2 12.3 0.014 14.9 7.5 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 CEH18536.1 - 1.2 8.9 8.9 2.1 8.1 8.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CEH18536.1 - 5.1 5.8 5.7 7.1 5.3 5.7 1.2 1 0 0 1 1 1 0 Presenilin Ribosomal_S13 PF00416.22 CEH18537.1 - 1.6e-54 183.7 2.0 1.8e-54 183.5 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CEH18537.1 - 0.009 14.8 0.0 0.0094 14.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 CEH18537.1 - 0.056 13.7 0.1 0.27 11.5 0.0 2.1 1 1 2 3 3 3 0 Helix-hairpin-helix motif CH PF00307.31 CEH18537.1 - 0.059 13.6 0.1 0.083 13.1 0.1 1.3 1 0 0 1 1 1 0 Calponin homology (CH) domain DUF2746 PF10874.8 CEH18537.1 - 0.098 13.1 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Cullin PF00888.22 CEH18538.1 - 6.2e-196 652.7 0.0 2.2e-194 647.6 0.0 3.0 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CEH18538.1 - 1.8e-29 101.6 0.8 4.3e-29 100.3 0.8 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Rrf2 PF02082.20 CEH18538.1 - 0.0066 16.8 0.0 0.025 14.9 0.0 1.9 1 0 0 1 1 1 1 Transcriptional regulator TetR_C_29 PF17938.1 CEH18538.1 - 0.1 12.7 0.1 0.34 11.0 0.1 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MIEAP PF16026.5 CEH18538.1 - 0.19 11.9 2.8 0.46 10.7 1.3 2.2 2 0 0 2 2 2 0 Mitochondria-eating protein CNH PF00780.22 CEH18539.1 - 2.6e-63 214.2 0.0 3.5e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 CEH18539.1 - 3.1e-11 43.5 0.0 6.4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 CEH18539.1 - 0.023 14.5 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain PH_16 PF17838.1 CEH18539.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 PH domain Homeodomain PF00046.29 CEH18540.1 - 1.7e-11 43.8 9.8 5.2e-09 35.8 0.3 2.4 1 1 1 2 2 2 2 Homeodomain CDC27 PF09507.10 CEH18541.1 - 4.2e-14 52.8 25.2 7.9e-11 42.0 25.2 2.7 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 DnaJ PF00226.31 CEH18542.1 - 4.3e-15 55.6 0.1 7.2e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 CEH18542.1 - 4.3e-13 48.8 0.0 7e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 CSL zinc finger Sugar_tr PF00083.24 CEH18543.1 - 9.6e-72 242.3 25.9 7.3e-33 114.1 6.6 3.1 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 CEH18543.1 - 3.5e-12 45.9 41.5 8.1e-11 41.4 10.9 3.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 CEH18543.1 - 0.25 11.9 4.4 0.63 10.6 3.2 2.3 1 1 0 1 1 1 0 Phage holin family 2 COesterase PF00135.28 CEH18545.1 - 3.3e-74 250.6 0.0 4.4e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CEH18545.1 - 1.6e-07 31.4 0.8 0.00099 19.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pyrid_oxidase_2 PF13883.6 CEH18546.1 - 3.2e-17 63.0 0.3 5e-17 62.4 0.3 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ThiF PF00899.21 CEH18547.1 - 7.1e-14 51.8 0.0 9.9e-13 48.0 0.0 2.3 1 1 0 1 1 1 1 ThiF family BcrAD_BadFG PF01869.20 CEH18547.1 - 0.04 13.4 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family E1_4HB PF16191.5 CEH18547.1 - 0.1 12.8 0.2 16 5.8 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-activating enzyme E1 four-helix bundle Pkinase PF00069.25 CEH18548.1 - 4.6e-60 203.2 0.0 6.7e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH18548.1 - 8.4e-30 103.9 0.0 1.3e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEH18548.1 - 0.0013 18.7 0.0 0.0053 16.7 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Fungal_KA1 PF16797.5 CEH18548.1 - 0.0042 16.8 0.0 0.43 10.3 0.0 2.3 2 0 0 2 2 2 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 CEH18548.1 - 0.072 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 CEH18548.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CEH18548.1 - 0.21 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 CEH18548.1 - 0.21 11.1 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Clathrin PF00637.20 CEH18551.1 - 7.3e-180 590.0 20.8 2e-32 112.0 0.1 7.8 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 CEH18551.1 - 7e-37 124.0 0.6 5.3e-07 29.6 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 CEH18551.1 - 6e-33 112.6 0.3 2.2e-32 110.7 0.3 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 CEH18551.1 - 1.3e-09 37.2 0.0 3.2e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 CEH18551.1 - 0.0015 17.7 2.6 0.23 10.5 0.0 4.0 4 0 0 4 4 4 1 Coatomer WD associated region TPR_2 PF07719.17 CEH18551.1 - 0.019 15.1 0.9 70 3.9 0.4 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEH18551.1 - 0.039 13.8 0.7 14 5.7 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEH18551.1 - 0.17 12.0 6.0 13 6.1 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEH18551.1 - 0.9 10.5 12.4 14 6.9 0.1 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat PPR PF01535.20 CEH18551.1 - 4 7.9 5.4 75 3.9 0.0 4.8 6 0 0 6 6 6 0 PPR repeat RSN1_7TM PF02714.15 CEH18554.1 - 5.1e-72 242.5 23.5 5.1e-72 242.5 23.5 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CEH18554.1 - 6.9e-36 124.1 0.0 9.7e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CEH18554.1 - 1.1e-21 77.2 0.0 1.1e-21 77.2 0.0 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4690 PF15756.5 CEH18554.1 - 0.12 13.0 0.6 0.36 11.4 0.0 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF3717 PF12512.8 CEH18554.1 - 0.14 12.0 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) Sm_multidrug_ex PF06695.11 CEH18554.1 - 0.31 11.7 0.0 0.31 11.7 0.0 3.3 4 1 0 4 4 4 0 Putative small multi-drug export protein Rad51 PF08423.11 CEH18555.1 - 3.2e-124 413.2 0.0 3.8e-124 413.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CEH18555.1 - 1.3e-10 41.2 0.1 1.8e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CEH18555.1 - 9.5e-10 38.4 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 CEH18555.1 - 6.4e-08 33.1 0.2 1.2e-07 32.2 0.2 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 CEH18555.1 - 5.8e-07 29.1 0.0 1.1e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.11 CEH18555.1 - 0.00053 19.2 0.9 0.041 13.0 0.8 2.1 1 1 1 2 2 2 2 PAXNEB protein AAA_24 PF13479.6 CEH18555.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CEH18555.1 - 0.002 17.5 0.1 0.031 13.6 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain HHH PF00633.23 CEH18555.1 - 0.022 14.6 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif GCP_N_terminal PF17681.1 CEH18556.1 - 6.9e-63 213.1 0.0 1.8e-62 211.7 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CEH18556.1 - 1.5e-41 142.9 4.9 1.5e-41 142.9 4.9 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal AsnC_trans_reg2 PF17805.1 CEH18560.1 - 0.22 11.7 0.4 0.45 10.7 0.4 1.4 1 0 0 1 1 1 0 AsnC-like ligand binding domain Methyltr_RsmB-F PF01189.17 CEH18561.1 - 2.4e-71 239.5 0.0 4.3e-71 238.7 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CEH18561.1 - 6.5e-08 33.0 0.0 1.7e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 CEH18561.1 - 0.0021 17.8 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.19 CEH18561.1 - 0.0049 17.0 0.0 0.03 14.4 0.1 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 CEH18561.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Tma16 PF11176.8 CEH18562.1 - 1.8e-32 112.3 5.1 2.2e-32 112.0 5.1 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DELLA PF12041.8 CEH18562.1 - 0.2 11.6 1.4 2.5 8.0 0.1 2.4 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal UPRTase PF14681.6 CEH18563.1 - 3.8e-77 258.4 0.0 4.4e-77 258.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CEH18563.1 - 8.2e-06 25.4 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NmrA PF05368.13 CEH18564.1 - 1.1e-23 84.0 0.0 1.5e-22 80.3 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CEH18564.1 - 1.3e-13 51.3 0.0 1.9e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 CEH18564.1 - 4.3e-07 30.2 0.1 7.5e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 CEH18564.1 - 9.4e-07 28.5 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 CEH18564.1 - 0.00026 21.5 0.0 0.013 16.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 CEH18564.1 - 0.00091 19.8 0.3 0.0024 18.4 0.3 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 CEH18564.1 - 0.0013 18.7 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 CEH18564.1 - 0.0017 17.4 0.1 0.0028 16.7 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 CEH18564.1 - 0.0018 18.4 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CEH18564.1 - 0.0024 17.9 0.1 0.0044 17.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CEH18564.1 - 0.0025 18.2 0.1 0.0044 17.4 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding HI0933_like PF03486.14 CEH18564.1 - 0.0027 16.5 0.3 0.0089 14.8 0.0 1.8 1 1 1 2 2 2 1 HI0933-like protein GDP_Man_Dehyd PF16363.5 CEH18564.1 - 0.0034 16.8 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ApbA PF02558.16 CEH18564.1 - 0.0061 16.2 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 CEH18564.1 - 0.015 15.5 0.1 0.025 14.9 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 CEH18564.1 - 0.018 14.5 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Pyr_redox_3 PF13738.6 CEH18564.1 - 0.045 13.0 0.1 0.072 12.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CEH18564.1 - 0.051 13.5 0.2 0.093 12.6 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 CEH18564.1 - 0.11 13.2 0.2 14 6.4 0.0 2.3 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEH18564.1 - 0.11 11.8 0.4 0.17 11.2 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 CEH18564.1 - 0.19 10.9 0.9 1.3 8.1 0.2 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rxt3 PF08642.10 CEH18565.1 - 1.4e-21 77.6 3.0 2.3e-20 73.6 0.0 3.0 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 CEH18565.1 - 0.011 15.9 0.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 0 LCCL domain TERB2 PF15101.6 CEH18565.1 - 0.051 13.6 2.2 0.094 12.8 2.2 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SART-1 PF03343.13 CEH18565.1 - 0.073 11.6 10.0 0.11 11.0 10.0 1.2 1 0 0 1 1 1 0 SART-1 family EPL1 PF10513.9 CEH18565.1 - 1.3 9.4 4.9 3.5 8.0 4.9 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like PHM7_cyt PF14703.6 CEH18565.1 - 1.6 8.9 6.7 3.2 8.0 6.7 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RR_TM4-6 PF06459.12 CEH18565.1 - 3.9 7.2 9.4 8.8 6.1 9.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PIEZO PF15917.5 CEH18565.1 - 4.7 6.6 12.1 9.1 5.7 12.1 1.3 1 0 0 1 1 1 0 Piezo MFS_1 PF07690.16 CEH18566.1 - 3.8e-42 144.5 39.6 2e-39 135.6 42.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CEH18566.1 - 5.1e-22 78.0 17.1 6.6e-22 77.7 17.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CEH18566.1 - 1.8e-10 40.3 8.4 1.8e-10 40.3 8.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter CNH PF00780.22 CEH18567.1 - 4.5e-82 275.7 0.0 8e-82 274.9 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 CEH18567.1 - 5.2e-36 124.6 0.0 7.4e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CEH18567.1 - 6.2e-33 113.8 0.0 2.2e-32 112.0 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 CEH18567.1 - 1.6e-13 50.5 0.0 3.4e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HRI1 PF16815.5 CEH18568.1 - 0.14 11.9 0.0 0.42 10.3 0.0 1.5 1 1 0 2 2 2 0 Protein HRI1 YjeF_N PF03853.15 CEH18569.1 - 1.4e-28 99.9 0.0 9.6e-28 97.2 0.0 2.0 2 0 0 2 2 2 1 YjeF-related protein N-terminus Peptidase_S24 PF00717.23 CEH18570.1 - 0.00022 21.1 0.0 0.14 12.1 0.0 2.5 2 1 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.9 CEH18570.1 - 0.00037 20.3 0.0 0.0032 17.2 0.0 2.4 2 1 0 2 2 2 1 Signal peptidase, peptidase S26 Methyltransf_PK PF05891.12 CEH18571.1 - 2e-48 164.8 0.1 3.7e-44 150.9 0.1 3.1 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 CEH18571.1 - 1.8e-07 31.1 0.0 4.9e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH18571.1 - 0.00083 20.0 0.0 0.002 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH18571.1 - 0.0016 19.1 0.0 0.0033 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH18571.1 - 0.0056 17.3 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Retrotran_gag_2 PF14223.6 CEH18572.1 - 0.0012 18.6 0.0 0.0029 17.3 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type SPA PF08616.10 CEH18573.1 - 1.1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 CEH18573.1 - 0.01 15.8 0.7 0.054 13.5 0.0 2.5 3 0 0 3 3 3 0 DENN (AEX-3) domain Avl9 PF09794.9 CEH18573.1 - 0.012 14.4 0.0 2.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Transport protein Avl9 Polysacc_synt_4 PF04669.13 CEH18574.1 - 2.4e-20 72.9 2.7 1.8e-18 66.8 2.7 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis HMG_box PF00505.19 CEH18575.1 - 2.3e-08 34.3 4.0 1.6e-05 25.2 2.2 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box Abhydrolase_6 PF12697.7 CEH18576.1 - 0.0051 17.4 0.2 0.0076 16.9 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CEH18576.1 - 0.046 13.6 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) GPI-anchored PF10342.9 CEH18577.1 - 3e-09 37.5 0.2 5.1e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 CEH18577.1 - 0.053 13.3 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) GATA PF00320.27 CEH18579.1 - 1.1e-27 95.3 16.2 5.4e-15 54.7 6.4 2.7 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.10 CEH18579.1 - 4.8e-05 23.4 1.2 0.32 11.2 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 CEH18579.1 - 0.00026 20.4 3.9 0.042 13.4 2.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Auto_anti-p27 PF06677.12 CEH18579.1 - 0.054 13.7 4.2 0.86 9.8 0.6 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF4892 PF16234.5 CEH18579.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4892) FYVE PF01363.21 CEH18579.1 - 5.8 7.1 5.8 12 6.1 0.4 2.6 3 0 0 3 3 3 0 FYVE zinc finger ETC_C1_NDUFA5 PF04716.14 CEH18581.1 - 1.1e-21 76.3 0.1 1.8e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Sds3 PF08598.11 CEH18582.1 - 1.6e-08 34.9 0.4 2.6e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 Sds3-like SOG2 PF10428.9 CEH18582.1 - 0.00086 18.6 3.9 0.00086 18.6 3.9 2.1 2 0 0 2 2 2 2 RAM signalling pathway protein Methyltransf_16 PF10294.9 CEH18583.1 - 9.6e-16 58.0 0.0 1e-07 31.9 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 CEH18583.1 - 0.00051 19.9 0.0 0.00093 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Glyco_trans_2_3 PF13632.6 CEH18586.1 - 6e-11 42.6 0.3 6e-11 42.6 0.3 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEH18586.1 - 0.00019 21.4 0.1 0.00046 20.1 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CEH18586.1 - 0.0083 15.9 0.2 1.5 8.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 DUF2786 PF10979.8 CEH18586.1 - 0.2 11.6 0.4 0.48 10.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Cellulase PF00150.18 CEH18587.1 - 2.4e-24 86.3 0.1 3.2e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AAA PF00004.29 CEH18588.1 - 1.1e-96 320.3 0.0 7.4e-47 159.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEH18588.1 - 1.3e-26 92.1 6.6 1.6e-13 50.2 0.3 3.1 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 CEH18588.1 - 8.4e-20 70.8 0.1 2.9e-19 69.0 0.1 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CEH18588.1 - 5.1e-15 55.6 0.0 5.6e-06 26.2 0.0 3.7 3 2 1 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CEH18588.1 - 1.8e-13 51.0 0.0 3.2e-07 30.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CEH18588.1 - 2.8e-12 47.0 0.1 6.8e-06 26.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 CEH18588.1 - 2.5e-11 43.7 0.5 1.7e-05 24.8 0.1 3.4 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEH18588.1 - 2.6e-11 44.2 0.4 0.0018 18.7 0.0 4.6 3 2 0 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.17 CEH18588.1 - 3.9e-11 42.6 0.0 7.9e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.13 CEH18588.1 - 2.2e-09 37.0 0.1 0.0014 17.9 0.1 2.7 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 CEH18588.1 - 7.2e-09 36.0 0.1 0.02 15.2 0.0 4.0 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CEH18588.1 - 7.8e-08 32.0 0.3 0.0053 16.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 CEH18588.1 - 2.4e-07 30.6 0.1 5.7e-06 26.2 0.0 3.0 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 CEH18588.1 - 2.6e-07 31.3 0.2 0.0098 16.4 0.0 3.3 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 CEH18588.1 - 4.7e-07 30.2 0.0 0.016 15.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 CEH18588.1 - 7.1e-07 29.1 0.0 0.018 14.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 CEH18588.1 - 1.2e-06 28.1 0.1 0.012 15.2 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 CEH18588.1 - 1.5e-06 27.5 0.1 0.0053 15.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 CEH18588.1 - 1.7e-06 28.1 0.0 0.018 15.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 CEH18588.1 - 1.9e-06 27.4 0.1 0.55 9.5 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 CEH18588.1 - 2.8e-06 27.0 2.1 0.3 10.6 0.1 3.9 2 2 2 4 4 3 2 AAA domain AAA_24 PF13479.6 CEH18588.1 - 5.7e-06 26.2 0.0 0.2 11.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 CEH18588.1 - 8.3e-06 26.1 0.0 0.081 13.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 CEH18588.1 - 8.7e-06 25.5 0.0 0.32 10.7 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 CEH18588.1 - 9.5e-06 24.9 0.0 0.0052 16.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 CEH18588.1 - 2.8e-05 24.7 0.0 0.074 13.6 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.18 CEH18588.1 - 3e-05 24.0 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein TsaE PF02367.17 CEH18588.1 - 7.7e-05 22.7 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CEH18588.1 - 0.00014 21.9 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 CEH18588.1 - 0.00014 21.7 0.0 0.65 9.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CEH18588.1 - 0.00015 21.3 0.2 0.65 9.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 CEH18588.1 - 0.00023 21.1 0.2 1 9.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 CEH18588.1 - 0.00026 20.9 0.2 0.15 11.9 0.0 2.9 3 0 0 3 3 3 1 NACHT domain ATPase_2 PF01637.18 CEH18588.1 - 0.00041 20.4 0.2 2.5 7.9 0.0 3.2 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_17 PF13207.6 CEH18588.1 - 0.00049 20.5 2.7 0.63 10.5 0.0 3.3 4 1 0 4 4 2 2 AAA domain AAA_30 PF13604.6 CEH18588.1 - 0.0007 19.4 0.5 1.2 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 CEH18588.1 - 0.00098 18.5 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 CEH18588.1 - 0.0012 18.6 0.0 0.15 11.8 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 CEH18588.1 - 0.0016 17.8 0.0 1.3 8.3 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin Sigma54_activ_2 PF14532.6 CEH18588.1 - 0.0022 18.1 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 CEH18588.1 - 0.0023 18.3 1.6 2.4 8.5 0.0 3.5 3 1 1 4 4 2 1 AAA domain NB-ARC PF00931.22 CEH18588.1 - 0.0026 17.0 0.0 0.48 9.6 0.0 2.5 3 0 0 3 3 2 1 NB-ARC domain NTPase_1 PF03266.15 CEH18588.1 - 0.014 15.3 0.4 2.6 7.9 0.0 3.5 3 0 0 3 3 3 0 NTPase IPT PF01745.16 CEH18588.1 - 0.026 13.9 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 CEH18588.1 - 0.027 14.2 0.3 4.7 6.9 0.0 3.0 3 0 0 3 3 2 0 Cytidylate kinase T2SSE PF00437.20 CEH18588.1 - 0.028 13.5 0.0 0.48 9.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AFG1_ATPase PF03969.16 CEH18588.1 - 0.038 12.9 0.1 5.5 5.8 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Zot PF05707.12 CEH18588.1 - 0.05 13.2 0.0 1.7 8.2 0.0 2.8 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.14 CEH18588.1 - 0.059 12.6 0.0 0.57 9.4 0.0 2.3 2 1 0 2 2 2 0 KAP family P-loop domain AAA_6 PF12774.7 CEH18588.1 - 0.14 11.1 0.1 6.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region UFD1 PF03152.14 CEH18588.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 PIF1 PF05970.14 CEH18588.1 - 0.17 11.0 0.0 5.7 6.0 0.0 2.7 2 0 0 2 2 2 0 PIF1-like helicase Hydin_ADK PF17213.3 CEH18588.1 - 0.84 9.9 2.5 44 4.3 0.0 3.7 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain PH PF00169.29 CEH18590.1 - 1.7e-11 44.6 0.0 7e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 CEH18590.1 - 0.02 15.3 0.3 0.14 12.6 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain NIF PF03031.18 CEH18592.1 - 5.6e-47 159.4 0.0 6.7e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_L5_C PF00673.21 CEH18593.1 - 1.3e-21 76.5 0.0 2.6e-21 75.6 0.0 1.5 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CEH18593.1 - 1.5e-19 70.1 0.0 2.5e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CEH18593.1 - 0.16 11.7 0.6 0.32 10.7 0.2 1.7 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain TatD_DNase PF01026.21 CEH18594.1 - 6.9e-49 166.5 0.0 9e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 CEH18594.1 - 5.5e-05 23.1 0.0 0.077 12.8 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase DUF4350 PF14258.6 CEH18595.1 - 0.0084 16.5 0.0 1.2 9.7 0.0 3.7 3 1 2 5 5 5 1 Domain of unknown function (DUF4350) DAG_kinase_N PF14513.6 CEH18595.1 - 0.014 15.6 0.3 0.26 11.5 0.0 3.0 4 1 1 5 5 5 0 Diacylglycerol kinase N-terminus Adeno_E1A PF02703.14 CEH18595.1 - 0.14 11.7 4.7 0.34 10.5 4.7 1.6 1 0 0 1 1 1 0 Early E1A protein Rib_recp_KP_reg PF05104.12 CEH18595.1 - 5.3 8.1 9.9 11 7.0 9.9 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region MGC-24 PF05283.11 CEH18595.1 - 5.5 7.4 8.6 9.5 6.7 8.6 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pyr_redox_2 PF07992.14 CEH18596.1 - 7.7e-08 31.9 0.0 1.4e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 CEH18596.1 - 1e-06 27.5 0.0 3.6e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 CEH18596.1 - 2.6e-06 26.8 0.0 4.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CEH18596.1 - 2.9e-06 26.8 0.0 5.6e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Gly_transf_sug PF04488.15 CEH18597.1 - 1.2e-08 35.5 0.0 2.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif RdRP PF05183.12 CEH18599.1 - 3.8e-161 537.7 0.0 4.9e-161 537.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Zn_clus PF00172.18 CEH18600.1 - 5.5e-11 42.4 6.7 8.9e-11 41.7 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_20 PF00982.21 CEH18602.1 - 3.2e-185 616.3 0.0 8.4e-138 460.0 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 CEH18602.1 - 0.014 14.9 0.1 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF2563 PF10817.8 CEH18602.1 - 1.2 9.7 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2563) His_Phos_1 PF00300.22 CEH18604.1 - 6.4e-16 58.6 0.7 8.2e-13 48.5 0.4 3.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF3446 PF11928.8 CEH18604.1 - 0.28 11.5 0.0 0.28 11.5 0.0 2.8 2 1 1 3 3 3 0 Early growth response N-terminal domain Orn_Arg_deC_N PF02784.16 CEH18605.1 - 1.2e-72 244.3 0.0 1.7e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CEH18605.1 - 1.6e-16 60.3 0.0 2.6e-16 59.7 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain E1-E2_ATPase PF00122.20 CEH18607.1 - 1.6e-21 76.6 0.0 4.3e-21 75.2 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CEH18607.1 - 1.2e-16 61.7 0.1 3e-09 37.5 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEH18607.1 - 0.024 14.7 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEH18607.1 - 0.065 13.0 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PAT1 PF09770.9 CEH18608.1 - 2e-122 410.2 4.9 4.5e-122 409.0 4.9 1.6 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DEAD PF00270.29 CEH18610.1 - 1.2e-45 155.4 0.0 2.4e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH18610.1 - 2.6e-30 105.0 0.0 5.2e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UTP25 PF06862.12 CEH18610.1 - 0.077 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 CEH18610.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit hDGE_amylase PF14701.6 CEH18611.1 - 3.9e-163 543.6 0.0 5.9e-163 543.0 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CEH18611.1 - 2.8e-109 365.6 0.0 4e-109 365.0 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CEH18611.1 - 3.2e-82 276.0 0.0 4.7e-82 275.5 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CEH18611.1 - 9.5e-22 76.9 0.0 1.9e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme GATA PF00320.27 CEH18614.1 - 2.9e-13 49.2 3.3 5e-13 48.4 3.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Pex2_Pex12 PF04757.14 CEH18615.1 - 2.8e-24 86.0 1.6 3.9e-24 85.5 1.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 CEH18615.1 - 1.7e-09 37.9 7.8 2.6e-09 37.3 7.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEH18615.1 - 4.2e-09 36.1 6.6 6.8e-09 35.4 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEH18615.1 - 8e-08 32.4 5.0 1.4e-07 31.7 5.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CEH18615.1 - 2.5e-07 30.4 6.4 4.3e-07 29.7 6.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEH18615.1 - 2.7e-07 30.4 5.5 4e-07 29.8 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH18615.1 - 5.3e-07 29.5 4.8 7.8e-07 29.0 4.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CEH18615.1 - 1.8e-05 24.5 7.1 2.9e-05 23.8 7.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEH18615.1 - 3.8e-05 23.6 2.8 3.9e-05 23.6 1.3 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CEH18615.1 - 0.0037 17.4 2.8 0.0037 17.4 2.8 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CEH18615.1 - 0.01 15.9 3.5 0.02 15.0 3.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CEH18615.1 - 0.039 13.8 5.0 0.057 13.2 5.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 CEH18615.1 - 0.057 13.7 3.3 0.11 12.8 3.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_10 PF16685.5 CEH18615.1 - 0.32 11.2 5.6 0.58 10.3 5.6 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 CEH18615.1 - 1.3 8.9 5.0 0.59 9.9 2.7 1.6 2 0 0 2 2 2 0 RING-like zinc finger Aminotran_3 PF00202.21 CEH18616.1 - 2.6e-79 266.8 0.0 3.1e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Esterase_phd PF10503.9 CEH18617.1 - 0.0014 18.1 0.1 0.0021 17.6 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 CEH18617.1 - 0.19 10.9 0.4 0.54 9.5 0.3 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 tRNA-synt_2b PF00587.25 CEH18620.1 - 9.1e-08 32.3 0.0 3.1e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEH18620.1 - 0.0055 16.8 0.4 3.8 7.7 0.0 2.7 1 1 1 2 2 2 2 Anticodon binding domain Plectin PF00681.20 CEH18620.1 - 0.0093 15.8 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 1 Plectin repeat SPG4 PF17325.2 CEH18620.1 - 8.4 7.5 7.1 79 4.4 0.0 3.1 3 0 0 3 3 3 0 Stationary phase protein 4 Fis1_TPR_N PF14852.6 CEH18621.1 - 1.6e-14 53.3 0.7 2.3e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEH18621.1 - 2.8e-10 40.1 1.0 4.3e-10 39.5 1.0 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 CEH18621.1 - 0.0012 18.8 0.2 0.0034 17.4 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEH18621.1 - 0.21 11.5 0.7 0.4 10.6 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_membrane_2 PF06472.15 CEH18622.1 - 8.1e-95 317.3 0.8 1.2e-94 316.8 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CEH18622.1 - 4.2e-14 53.2 0.0 3.3e-13 50.3 0.0 2.5 3 0 0 3 3 3 1 ABC transporter AAA_23 PF13476.6 CEH18622.1 - 0.0016 19.0 0.2 1.6 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEH18622.1 - 0.0016 18.8 0.5 0.0063 16.9 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CEH18622.1 - 0.0039 17.0 0.0 0.018 14.8 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 CEH18622.1 - 0.0085 16.5 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEH18622.1 - 0.013 16.1 0.0 0.03 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CEH18622.1 - 0.024 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 CEH18622.1 - 0.046 13.4 0.1 0.24 11.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CEH18622.1 - 0.049 13.0 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CEH18622.1 - 0.084 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) baeRF_family12 PF18856.1 CEH18622.1 - 0.089 13.4 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 Cytidylate_kin PF02224.18 CEH18622.1 - 0.11 12.2 0.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase NACHT PF05729.12 CEH18622.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_12 PF13087.6 CEH18623.1 - 5e-34 117.7 0.0 1e-33 116.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEH18623.1 - 4.3e-12 46.4 0.4 3.8e-08 33.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 CEH18623.1 - 1.4e-05 25.5 0.0 5.5e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CEH18623.1 - 0.0033 16.7 0.4 0.033 13.4 0.0 2.9 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CEH18623.1 - 0.0061 16.3 0.0 0.044 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CEH18623.1 - 0.068 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4512 PF14975.6 CEH18625.1 - 0.11 13.3 0.5 1.7 9.4 0.5 3.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF1604 PF07713.13 CEH18627.1 - 9.7e-32 108.7 13.3 2.2e-28 97.9 3.2 3.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1604) G-patch PF01585.23 CEH18627.1 - 6.7e-06 25.9 0.3 2.4e-05 24.2 0.3 2.0 1 0 0 1 1 1 1 G-patch domain PAN_4 PF14295.6 CEH18628.1 - 0.058 13.3 3.1 0.15 12.0 3.1 1.7 1 0 0 1 1 1 0 PAN domain DUF3410 PF11890.8 CEH18629.1 - 0.07 12.9 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) F-box-like PF12937.7 CEH18631.1 - 0.029 14.2 0.3 0.068 13.1 0.3 1.6 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 CEH18632.1 - 1e-23 83.9 43.6 1e-23 83.9 43.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DEC-1_N PF04625.13 CEH18632.1 - 0.91 8.5 3.3 9.4 5.1 4.1 1.9 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region RHS PF03527.14 CEH18632.1 - 1.3 8.9 3.2 25 4.7 0.2 2.4 2 0 0 2 2 2 0 RHS protein Abhydrolase_6 PF12697.7 CEH18634.1 - 3.3e-15 57.3 3.8 3.3e-15 57.3 3.8 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEH18634.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold ketoacyl-synt PF00109.26 CEH18635.1 - 1.9e-51 175.1 0.7 3.8e-51 174.1 0.7 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CEH18635.1 - 4.9e-40 137.3 0.2 1.4e-39 135.9 0.2 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 CEH18635.1 - 2.3e-38 132.5 0.8 6.8e-38 130.9 0.8 1.8 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 CEH18635.1 - 9.2e-32 109.5 0.1 2.8e-31 108.0 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 CEH18635.1 - 1.3e-30 106.7 2.1 1.7e-30 106.3 0.2 2.2 3 0 0 3 3 3 1 Polyketide synthase dehydratase Thioesterase PF00975.20 CEH18635.1 - 3.1e-11 43.8 0.3 1.5e-10 41.6 0.1 2.2 2 0 0 2 2 2 1 Thioesterase domain KAsynt_C_assoc PF16197.5 CEH18635.1 - 2.4e-10 40.9 0.0 7.6e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 CEH18635.1 - 2e-08 34.4 0.3 4.4e-08 33.4 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 CEH18635.1 - 1.2e-07 31.4 0.6 3.9e-07 29.7 0.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 CEH18635.1 - 1.1e-06 28.6 0.0 2.6e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH18635.1 - 0.00046 20.0 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.10 CEH18635.1 - 0.00063 19.5 1.7 0.0013 18.5 0.1 2.4 3 0 0 3 3 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_25 PF13649.6 CEH18635.1 - 0.00088 19.9 0.0 0.0032 18.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 CEH18635.1 - 0.0013 18.2 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.12 CEH18635.1 - 0.011 16.4 0.0 0.041 14.6 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CEH18635.1 - 0.092 13.4 0.0 0.29 11.8 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain RT_RNaseH_2 PF17919.1 CEH18636.1 - 1.8e-25 88.9 0.2 1.3e-14 54.1 0.1 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEH18636.1 - 6.6e-25 87.9 0.0 1.1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CEH18636.1 - 9.2e-16 58.0 0.0 1.9e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 CEH18636.1 - 0.07 13.8 0.0 0.38 11.4 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease FAM104 PF15434.6 CEH18637.1 - 0.035 14.7 3.7 0.042 14.4 3.7 1.1 1 0 0 1 1 1 0 Family 104 PI-PLC-X PF00388.19 CEH18641.1 - 2.4e-43 147.2 0.0 3.5e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CEH18641.1 - 1.7e-34 118.6 0.0 3.1e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CEH18641.1 - 0.00018 21.7 0.0 0.00051 20.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain WH2 PF02205.20 CEH18642.1 - 4.9e-05 23.0 0.8 0.00014 21.6 0.8 1.8 1 0 0 1 1 1 1 WH2 motif WAPL PF07814.13 CEH18643.1 - 4.3e-08 32.3 1.8 6.2e-08 31.8 0.2 2.0 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin DUF1860 PF08949.10 CEH18643.1 - 0.13 12.0 0.6 0.27 11.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) EGF_2 PF07974.13 CEH18643.1 - 0.2 12.1 0.6 0.4 11.1 0.6 1.5 1 0 0 1 1 1 0 EGF-like domain DUF5316 PF17247.2 CEH18646.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5316) TAFII28 PF04719.14 CEH18650.1 - 1.6e-23 82.6 1.2 5.5e-23 80.9 1.2 1.9 1 1 0 1 1 1 1 hTAFII28-like protein conserved region MlaC PF05494.12 CEH18650.1 - 0.023 14.5 0.4 0.038 13.7 0.4 1.3 1 0 0 1 1 1 0 MlaC protein RNA_pol_3_Rpc31 PF11705.8 CEH18650.1 - 0.21 11.8 11.6 0.72 10.1 2.4 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 RPN2_C PF18004.1 CEH18650.1 - 2.4 8.1 16.5 4.7 7.1 6.5 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Myc_N PF01056.18 CEH18650.1 - 7.7 6.3 18.2 7.4 6.4 6.2 2.3 1 1 1 2 2 2 0 Myc amino-terminal region GIY-YIG PF01541.24 CEH18651.1 - 3.1e-06 27.4 0.0 1e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 GIY-YIG catalytic domain FANCL_C PF11793.8 CEH18651.1 - 0.058 13.6 1.7 0.77 10.0 0.2 2.6 3 0 0 3 3 3 0 FANCL C-terminal domain zf-RING_2 PF13639.6 CEH18651.1 - 1.6 9.2 6.6 3.1 8.2 0.1 3.3 3 0 0 3 3 3 0 Ring finger domain TPR_1 PF00515.28 CEH18652.1 - 5e-38 127.4 22.6 2.8e-06 26.9 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 CEH18652.1 - 5.6e-35 119.1 5.6 5.1e-17 61.6 1.4 3.6 5 0 0 5 5 3 2 STI1 domain TPR_2 PF07719.17 CEH18652.1 - 5.8e-28 94.7 34.0 0.00059 19.7 0.0 9.8 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 CEH18652.1 - 1.5e-19 68.5 22.2 6.7e-05 22.8 0.2 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 CEH18652.1 - 1.7e-17 63.8 22.1 0.0011 19.5 0.0 6.3 6 1 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEH18652.1 - 2.5e-17 62.3 22.0 0.00048 19.8 0.0 9.0 6 2 3 9 9 9 4 TPR repeat TPR_19 PF14559.6 CEH18652.1 - 3.9e-15 56.1 21.3 0.0002 21.8 2.6 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEH18652.1 - 6.7e-13 48.7 22.1 5.3e-09 36.2 1.3 6.9 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEH18652.1 - 1.9e-10 40.7 21.2 0.92 10.5 0.0 8.8 5 3 4 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEH18652.1 - 5.7e-08 32.6 7.6 0.028 14.8 0.0 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEH18652.1 - 3.1e-06 27.3 5.8 0.23 11.6 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEH18652.1 - 6.5e-05 22.7 18.1 0.055 13.5 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH18652.1 - 0.012 15.8 20.1 0.02 15.1 3.8 4.4 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CEH18652.1 - 0.012 16.2 16.6 7.8 7.4 0.0 7.7 7 1 0 7 7 7 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CEH18652.1 - 0.097 12.8 4.2 0.11 12.5 1.0 2.6 3 0 0 3 3 2 0 Anaphase-promoting complex subunit 5 Fibrillarin_2 PF10113.9 CEH18652.1 - 0.11 11.1 0.9 0.18 10.4 0.9 1.2 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein NSF PF02071.20 CEH18652.1 - 1.2 10.2 3.5 1.5e+02 3.9 0.0 4.7 4 0 0 4 4 2 0 Aromatic-di-Alanine (AdAR) repeat TPR_10 PF13374.6 CEH18652.1 - 1.9 8.5 24.6 4.2 7.4 0.0 7.5 8 1 1 9 9 9 0 Tetratricopeptide repeat Gly_radical PF01228.21 CEH18652.1 - 2.6 8.6 4.7 4 8.0 0.1 3.3 4 1 0 4 4 3 0 Glycine radical Pyr_redox_2 PF07992.14 CEH18653.1 - 3.6e-06 26.4 0.0 6.1e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEH18653.1 - 0.015 15.2 0.0 0.055 13.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CEH18653.1 - 0.064 13.5 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Kinesin PF00225.23 CEH18653.1 - 0.18 10.7 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain MIP PF00230.20 CEH18654.1 - 2.2e-49 168.2 14.8 3.1e-49 167.7 14.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF2456 PF10445.9 CEH18655.1 - 6e-15 55.1 2.3 1.4e-14 53.9 2.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) DUF383 PF04063.14 CEH18656.1 - 6.5e-38 130.3 0.0 1.8e-37 128.9 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CEH18656.1 - 3.8e-18 65.1 2.4 1.1e-17 63.6 2.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) SR-25 PF10500.9 CEH18656.1 - 1.3 8.5 12.8 2.6 7.6 12.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HEAT PF02985.22 CEH18656.1 - 3.6 8.1 5.6 1.9 9.0 0.1 3.4 3 0 0 3 3 3 0 HEAT repeat WD40 PF00400.32 CEH18657.1 - 1.1e-38 130.5 12.4 1.8e-05 25.4 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH18657.1 - 2.3e-17 63.1 1.2 0.0082 16.4 0.1 6.2 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain SH3_2 PF07653.17 CEH18658.1 - 2.5e-06 27.1 0.0 5.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEH18658.1 - 0.00085 18.9 0.1 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CEH18658.1 - 0.0024 17.7 0.0 0.0057 16.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Fasciclin PF02469.22 CEH18659.1 - 1.9e-29 102.5 0.1 7.9e-20 71.4 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain COPIIcoated_ERV PF07970.12 CEH18660.1 - 2.5e-38 132.2 0.1 4.3e-38 131.4 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CEH18660.1 - 4.1e-22 78.3 0.0 7.1e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Adaptin_N PF01602.20 CEH18663.1 - 4e-143 477.7 2.8 4.7e-143 477.5 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CEH18663.1 - 5.7e-19 68.5 0.1 1.2e-18 67.4 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CEH18663.1 - 3.3e-05 24.0 4.2 0.0065 16.5 0.1 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEH18663.1 - 0.00012 22.4 4.4 1.9 8.9 0.1 4.7 4 0 0 4 4 4 2 HEAT repeats Peptidase_M73 PF12389.8 CEH18663.1 - 0.011 15.6 0.6 0.049 13.5 0.1 2.1 2 0 0 2 2 2 0 Camelysin metallo-endopeptidase NopRA1 PF16201.5 CEH18663.1 - 0.039 13.5 0.0 0.97 9.0 0.0 2.6 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 EXOSC1 PF10447.9 CEH18663.1 - 0.08 13.6 0.9 5.4 7.7 0.1 2.8 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 UDPGP PF01704.18 CEH18663.1 - 0.14 10.7 0.2 0.24 10.0 0.2 1.2 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase V-ATPase_H_C PF11698.8 CEH18663.1 - 0.36 11.0 1.2 6.2 7.0 0.1 3.1 2 1 1 3 3 3 0 V-ATPase subunit H UPF0086 PF01868.16 CEH18666.1 - 1.5e-19 69.7 0.0 5.7e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function UPF0086 MMS1_N PF10433.9 CEH18667.1 - 8.9e-142 473.1 0.0 1.9e-141 472.0 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CEH18667.1 - 3.4e-87 292.8 0.0 7.3e-87 291.7 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region Nup160 PF11715.8 CEH18667.1 - 0.27 9.9 0.3 17 3.9 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PX PF00787.24 CEH18670.1 - 3.9e-22 78.4 0.6 8.1e-22 77.3 0.6 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CEH18670.1 - 1.4e-07 31.3 3.2 0.00029 20.5 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Surfac_D-trimer PF09006.11 CEH18670.1 - 0.1 12.5 0.0 0.99 9.4 0.1 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Mito_carr PF00153.27 CEH18671.1 - 2.4e-30 104.3 5.5 1.8e-19 69.4 0.1 2.6 3 0 0 3 3 3 2 Mitochondrial carrier protein UQ_con PF00179.26 CEH18672.1 - 1.5e-46 157.5 0.0 1.8e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEH18672.1 - 0.00047 19.9 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CEH18672.1 - 0.017 15.0 0.1 0.033 14.1 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 CEH18672.1 - 0.072 13.4 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain DAHP_synth_1 PF00793.20 CEH18673.1 - 1.5e-97 325.8 0.0 1.9e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Pkinase PF00069.25 CEH18674.1 - 1.8e-69 234.0 0.0 2.4e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH18674.1 - 6.2e-25 87.9 0.0 1.1e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase IF-2B PF01008.17 CEH18675.1 - 3.1e-47 161.1 0.1 3.6e-47 160.9 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family FliG_C PF01706.16 CEH18675.1 - 0.071 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 FliG C-terminal domain Sterol_MT_C PF08498.10 CEH18676.1 - 4.6e-29 100.5 1.3 7.1e-29 99.9 1.3 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CEH18676.1 - 3.9e-20 72.3 0.0 7.9e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH18676.1 - 2.7e-18 66.2 0.0 4.9e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH18676.1 - 5.4e-17 62.3 0.0 1e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH18676.1 - 7e-15 55.2 0.0 9.9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEH18676.1 - 9.7e-14 51.3 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CEH18676.1 - 6.4e-11 42.9 0.0 1.8e-10 41.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEH18676.1 - 2e-07 30.6 0.0 3.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CEH18676.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 CEH18676.1 - 0.00095 18.4 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.12 CEH18676.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CEH18676.1 - 0.0016 18.5 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CEH18676.1 - 0.0029 17.2 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_29 PF03141.16 CEH18676.1 - 0.0049 15.5 0.0 0.0079 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 CEH18676.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CEH18676.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain UPF0020 PF01170.18 CEH18676.1 - 0.025 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 CEH18676.1 - 0.042 13.2 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 CEH18676.1 - 0.065 14.3 0.0 0.15 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 CEH18676.1 - 0.13 11.6 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PX PF00787.24 CEH18677.1 - 3e-11 43.3 0.0 4.8e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 PX domain MFS_1 PF07690.16 CEH18678.1 - 1.6e-28 99.7 21.4 1.6e-28 99.7 21.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily rve PF00665.26 CEH18679.1 - 3.4e-19 69.2 0.0 8.1e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 CEH18679.1 - 1.1e-05 25.3 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease rve_3 PF13683.6 CEH18679.1 - 0.011 15.5 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 0 Integrase core domain DDE_Tnp_IS240 PF13610.6 CEH18679.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 DDE domain Flavokinase PF01687.17 CEH18680.1 - 0.085 13.2 0.0 0.38 11.1 0.0 1.8 1 1 1 2 2 2 0 Riboflavin kinase Tristanin_u2 PF16638.5 CEH18681.1 - 0.046 14.6 0.6 0.046 14.6 0.6 3.1 3 0 0 3 3 3 0 Unstructured region on methyltransferase between zinc-fingers Btz PF09405.10 CEH18681.1 - 0.29 11.4 8.8 0.36 11.1 0.9 3.2 3 0 0 3 3 3 0 CASC3/Barentsz eIF4AIII binding Pro_isomerase PF00160.21 CEH18682.1 - 2.7e-45 154.5 0.0 2e-44 151.7 0.0 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 CEH18682.1 - 6.2e-06 25.8 0.9 6e-05 22.5 0.0 2.2 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 CEH18682.1 - 0.025 14.7 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein RCR PF12273.8 CEH18686.1 - 0.031 14.9 0.0 0.04 14.6 0.0 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DivIC PF04977.15 CEH18688.1 - 0.00031 20.5 20.5 0.021 14.6 8.9 2.7 1 1 2 3 3 3 2 Septum formation initiator BRE1 PF08647.11 CEH18688.1 - 0.0024 17.9 11.1 0.0024 17.9 11.1 2.0 1 1 0 2 2 2 1 BRE1 E3 ubiquitin ligase FUSC PF04632.12 CEH18688.1 - 0.009 14.6 0.7 0.011 14.3 0.7 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family CENP-H PF05837.12 CEH18688.1 - 0.0099 16.3 17.8 0.044 14.2 11.9 2.1 1 1 1 2 2 2 2 Centromere protein H (CENP-H) DUF3450 PF11932.8 CEH18688.1 - 0.064 12.5 12.5 0.086 12.1 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2244 PF10003.9 CEH18688.1 - 0.068 12.8 0.2 4 7.1 0.2 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) ZapB PF06005.12 CEH18688.1 - 0.11 12.9 25.4 0.12 12.8 9.1 2.7 1 1 1 2 2 2 0 Cell division protein ZapB MRP-L47 PF06984.13 CEH18688.1 - 0.17 12.0 7.2 5 7.3 6.1 2.6 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF4140 PF13600.6 CEH18688.1 - 0.37 11.2 6.3 0.38 11.2 2.1 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) JIP_LZII PF16471.5 CEH18688.1 - 0.42 10.8 7.0 2 8.6 1.0 2.5 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II HALZ PF02183.18 CEH18688.1 - 0.57 10.4 14.6 0.16 12.2 3.8 2.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper Spc7 PF08317.11 CEH18688.1 - 0.67 8.8 13.3 0.93 8.3 13.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Seadorna_VP6 PF07407.11 CEH18688.1 - 0.88 8.4 7.3 1.9 7.4 2.3 2.0 1 1 1 2 2 2 0 Seadornavirus VP6 protein YabA PF06156.13 CEH18688.1 - 1.6 9.4 12.9 20 5.9 12.9 2.2 1 1 0 1 1 1 0 Initiation control protein YabA ADIP PF11559.8 CEH18688.1 - 4.8 7.3 21.1 1.5 8.9 17.4 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 CEH18688.1 - 5.5 7.5 16.9 0.88 10.1 12.2 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region CCDC92 PF14916.6 CEH18689.1 - 0.00053 19.7 0.5 0.0011 18.7 0.5 1.6 1 1 0 1 1 1 1 Coiled-coil domain of unknown function Herpes_BLRF2 PF05812.12 CEH18689.1 - 0.00071 19.7 0.5 0.00071 19.7 0.5 2.4 2 1 0 2 2 2 1 Herpesvirus BLRF2 protein ADIP PF11559.8 CEH18689.1 - 0.0038 17.3 6.8 0.0038 17.3 6.8 2.0 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 CEH18689.1 - 0.009 16.3 2.4 0.086 13.2 0.5 2.4 1 1 1 2 2 2 1 TSC-22/dip/bun family YabA PF06156.13 CEH18689.1 - 0.011 16.4 2.7 0.011 16.4 2.7 1.6 2 0 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 CEH18689.1 - 0.013 15.7 2.0 0.021 15.1 1.4 1.6 1 1 0 1 1 1 0 Homeobox associated leucine zipper ATG16 PF08614.11 CEH18689.1 - 0.016 15.4 11.8 0.02 15.1 10.5 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Macoilin PF09726.9 CEH18689.1 - 0.028 13.0 7.0 0.034 12.7 7.0 1.1 1 0 0 1 1 1 0 Macoilin family SlyX PF04102.12 CEH18689.1 - 0.041 14.5 6.3 1.2 9.8 1.7 2.4 1 1 1 2 2 2 0 SlyX APC_N_CC PF16689.5 CEH18689.1 - 0.047 13.8 1.6 0.11 12.6 1.2 1.8 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain JIP_LZII PF16471.5 CEH18689.1 - 0.06 13.5 2.6 0.3 11.3 0.2 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II FAM76 PF16046.5 CEH18689.1 - 0.11 11.8 9.2 0.19 11.0 9.2 1.4 1 0 0 1 1 1 0 FAM76 protein ABC_tran_CTD PF16326.5 CEH18689.1 - 0.16 12.2 7.6 0.28 11.5 1.5 2.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain DivIC PF04977.15 CEH18689.1 - 0.25 11.1 15.0 0.25 11.1 1.6 3.0 1 1 2 3 3 3 0 Septum formation initiator DUF641 PF04859.12 CEH18689.1 - 0.26 11.6 8.1 0.1 12.9 4.5 1.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF45 PF01863.17 CEH18689.1 - 0.27 11.2 3.3 0.34 10.9 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 USP8_interact PF08941.10 CEH18689.1 - 0.42 10.4 5.5 0.045 13.6 1.3 1.5 2 0 0 2 2 2 0 USP8 interacting DUF16 PF01519.16 CEH18689.1 - 0.65 10.5 6.4 1.6 9.2 6.4 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 KLRAQ PF10205.9 CEH18689.1 - 0.69 10.2 10.9 0.064 13.5 4.7 1.9 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein UPF0242 PF06785.11 CEH18689.1 - 1 9.5 11.6 3.4 7.7 10.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 CEH18689.1 - 3.4 7.8 11.0 0.11 12.6 2.2 2.5 2 1 1 3 3 3 0 bZIP transcription factor DUF4407 PF14362.6 CEH18689.1 - 4.4 6.6 14.0 1.3 8.3 3.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Lgl_C PF08596.10 CEH18691.1 - 1.5e-14 53.5 0.0 1.6e-09 37.0 0.0 3.0 3 0 0 3 3 3 2 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 CEH18691.1 - 9.3e-05 22.7 0.0 0.029 14.6 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEH18691.1 - 0.003 18.3 2.8 0.12 13.3 0.1 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Frtz PF11768.8 CEH18691.1 - 0.024 13.0 0.0 0.044 12.1 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz ApbE PF02424.15 CEH18692.1 - 0.0095 15.5 0.6 0.015 14.9 0.6 1.4 1 0 0 1 1 1 1 ApbE family DUF2184 PF09950.9 CEH18692.1 - 0.011 15.1 0.2 0.023 14.1 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) Zwilch PF09817.9 CEH18692.1 - 0.089 11.2 0.2 0.13 10.7 0.2 1.1 1 0 0 1 1 1 0 RZZ complex, subunit zwilch DUF4649 PF15507.6 CEH18692.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) Autophagy_N PF03986.13 CEH18693.1 - 8.2e-37 126.2 1.1 1.8e-20 73.3 0.1 3.2 3 0 0 3 3 3 2 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CEH18693.1 - 1.4e-18 67.2 0.1 2.3e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CEH18693.1 - 1.9e-13 49.7 0.6 3.2e-13 48.9 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Meth_synt_2 PF01717.18 CEH18694.1 - 3.3e-11 43.0 0.0 5.7e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Thiolase_C PF02803.18 CEH18695.1 - 7.9e-43 145.0 0.1 1.1e-42 144.5 0.1 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 CEH18695.1 - 3.9e-30 105.1 0.0 8.4e-30 104.0 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain PALP PF00291.25 CEH18696.1 - 4.6e-31 108.3 0.1 8.4e-31 107.5 0.1 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IBR PF01485.21 CEH18697.1 - 1e-09 38.5 17.8 2.8e-09 37.0 9.5 3.1 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain PGAP1 PF07819.13 CEH18698.1 - 1.3e-56 192.0 0.0 1.8e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 CEH18698.1 - 0.00049 19.4 0.0 0.00081 18.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 CEH18698.1 - 0.0051 16.4 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 CEH18698.1 - 0.0086 15.4 0.0 0.021 14.2 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 CEH18698.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative esterase Abhydrolase_8 PF06259.12 CEH18698.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase Lipase_3 PF01764.25 CEH18698.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) FCH PF00611.23 CEH18699.1 - 7.4e-14 51.8 2.7 3.6e-13 49.6 0.2 2.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 CEH18699.1 - 9.6e-11 41.1 0.2 1.8e-10 40.2 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEH18699.1 - 7.3e-10 38.6 0.1 1.2e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEH18699.1 - 2e-06 27.4 0.0 3.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Lebercilin PF15619.6 CEH18699.1 - 0.71 9.5 4.9 0.25 11.0 1.2 1.9 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TPR_MLP1_2 PF07926.12 CEH18699.1 - 7.6 6.6 10.4 1.6 8.8 5.9 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein She9_MDM33 PF05546.11 CEH18700.1 - 1.2e-42 146.0 5.0 1.3e-42 145.9 5.0 1.0 1 0 0 1 1 1 1 She9 / Mdm33 family PepSY_TM PF03929.16 CEH18700.1 - 0.00045 20.0 0.1 0.00052 19.8 0.1 1.0 1 0 0 1 1 1 1 PepSY-associated TM region DUF1133 PF06576.11 CEH18700.1 - 0.0084 15.5 0.4 0.0096 15.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1133) Cas_Cas02710 PF09670.10 CEH18700.1 - 0.022 13.6 4.6 0.028 13.2 4.6 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Uds1 PF15456.6 CEH18700.1 - 1.4 9.1 12.2 2.3 8.4 12.2 1.3 1 1 0 1 1 1 0 Up-regulated During Septation ZapB PF06005.12 CEH18700.1 - 2.7 8.5 12.1 2.1 8.9 6.6 2.1 2 0 0 2 2 2 0 Cell division protein ZapB NDUFA12 PF05071.16 CEH18701.1 - 4.9e-09 36.9 0.4 1.2e-08 35.6 0.0 1.8 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 FAD_binding_4 PF01565.23 CEH18701.1 - 0.12 12.1 1.1 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain 4HBT_3 PF13622.6 CEH18702.1 - 8.1e-22 78.7 0.3 3.2e-19 70.2 0.3 2.1 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF3046 PF11248.8 CEH18702.1 - 0.003 17.9 0.1 4.5 7.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3046) LRR_10 PF18805.1 CEH18702.1 - 0.73 9.5 2.5 36 4.1 0.1 2.9 3 0 0 3 3 3 0 Leucine-rich repeat AAA_5 PF07728.14 CEH18703.1 - 1.7e-58 196.5 0.0 2.3e-25 89.2 0.0 4.1 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEH18703.1 - 0.0035 17.8 1.0 2.7 8.3 0.0 4.0 3 1 0 3 3 3 2 AAA ATPase domain Peptidase_C97 PF05903.14 CEH18704.1 - 1.7e-17 63.6 0.0 1.1e-12 48.0 0.0 2.1 2 0 0 2 2 2 2 PPPDE putative peptidase domain Thioredoxin PF00085.20 CEH18705.1 - 2.4e-31 107.8 0.0 2.8e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEH18705.1 - 1.6e-08 35.0 0.1 3.1e-07 30.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CEH18705.1 - 6e-06 26.1 0.0 7.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CEH18705.1 - 1.2e-05 24.8 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CEH18705.1 - 3.3e-05 24.1 0.0 0.01 16.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 CEH18705.1 - 0.00032 20.4 0.1 0.018 14.8 0.0 2.1 1 1 1 2 2 2 1 Redoxin Glutaredoxin PF00462.24 CEH18705.1 - 0.0024 18.1 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 CEH18705.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 CEH18705.1 - 0.034 14.1 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF2847 PF11009.8 CEH18705.1 - 0.057 13.3 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DIM1 PF02966.16 CEH18705.1 - 0.091 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_5 PF13743.6 CEH18705.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 CEH18705.1 - 0.15 12.1 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain NTS_2 PF15448.6 CEH18705.1 - 0.16 12.4 0.1 4.4 7.8 0.0 2.2 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein zf-H2C2_2 PF13465.6 CEH18707.1 - 1.5e-11 44.2 16.0 1.8e-06 28.1 0.1 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CEH18707.1 - 8.7e-11 41.7 17.5 0.0001 22.6 3.0 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEH18707.1 - 9.7e-11 41.6 12.8 0.0045 17.7 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEH18707.1 - 1e-05 25.7 1.8 1.4 9.3 0.0 3.7 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CEH18707.1 - 0.11 12.3 1.8 15 5.5 0.7 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type IBR PF01485.21 CEH18707.1 - 0.33 11.2 3.6 0.18 12.0 1.6 1.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-H2C2_5 PF13909.6 CEH18707.1 - 0.81 9.5 9.4 0.06 13.1 0.7 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CEH18707.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.3 3 1 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CEH18707.1 - 1.2 9.6 4.7 8.6 6.9 0.0 3.5 3 1 0 3 3 3 0 Zinc-finger of C2H2 type Abhydrolase_6 PF12697.7 CEH18708.1 - 1.9e-08 35.2 0.6 3e-08 34.6 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH18708.1 - 8.7e-07 28.4 0.0 2.3e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CEH18708.1 - 1.6e-05 24.9 0.1 3.5e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CEH18708.1 - 5.2e-05 23.0 0.0 8.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CEH18708.1 - 0.0034 17.5 0.0 0.0091 16.1 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.18 CEH18708.1 - 0.045 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) UNC-93 PF05978.16 CEH18709.1 - 3.4e-06 26.8 3.0 3.4e-06 26.8 3.0 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CEH18709.1 - 3.5e-06 26.2 32.2 3.5e-06 26.2 32.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily BRCA2 PF00634.18 CEH18709.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 BRCA2 repeat MgtE PF01769.16 CEH18709.1 - 2.1 8.7 10.3 0.25 11.7 0.3 3.1 3 0 0 3 3 3 0 Divalent cation transporter Asp PF00026.23 CEH18710.1 - 2.1e-32 112.8 9.2 8.4e-32 110.8 9.2 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CEH18710.1 - 3.6e-06 27.5 1.9 0.019 15.6 0.6 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CEH18710.1 - 0.00018 22.0 1.0 0.47 11.1 0.1 3.2 4 0 0 4 4 4 2 gag-polyprotein putative aspartyl protease Acetyltransf_7 PF13508.7 CEH18711.1 - 1.9e-08 34.6 0.0 2.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEH18711.1 - 3.8e-08 33.3 0.0 4.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEH18711.1 - 7.6e-07 29.4 0.0 9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CEH18711.1 - 0.00015 21.7 0.0 0.00019 21.3 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CEH18711.1 - 0.021 14.9 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4149 PF13664.6 CEH18712.1 - 5e-19 68.5 0.3 5e-19 68.5 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) RGS PF00615.19 CEH18713.1 - 7.5e-12 45.6 0.0 7.5e-07 29.4 0.0 2.5 2 1 0 2 2 2 2 Regulator of G protein signaling domain Metallophos_2 PF12850.7 CEH18714.1 - 1.1e-20 74.4 0.1 2e-20 73.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CEH18714.1 - 4.1e-05 24.2 2.7 0.11 13.0 0.2 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase SAPS PF04499.15 CEH18714.1 - 0.28 9.9 5.4 0.34 9.6 5.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CEH18714.1 - 3.5 6.3 10.0 4.6 5.9 10.0 1.1 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 CEH18714.1 - 4.7 6.5 20.2 6.3 6.1 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NIPSNAP PF07978.13 CEH18715.1 - 1.2e-37 128.2 1.3 6.4e-27 93.8 0.1 2.2 2 0 0 2 2 2 2 NIPSNAP LytR_C PF13399.6 CEH18715.1 - 0.039 14.9 0.4 0.093 13.7 0.4 1.8 1 1 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator DUF1754 PF08555.10 CEH18717.1 - 0.053 14.3 0.5 0.091 13.6 0.5 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF4719 PF15843.5 CEH18717.1 - 3.7 7.6 5.6 0.64 10.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) STE2 PF02116.15 CEH18719.1 - 0.003 16.9 10.5 0.0041 16.5 8.2 1.9 1 1 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR SLC3A2_N PF16028.5 CEH18719.1 - 0.14 11.7 1.7 0.23 11.0 0.1 2.2 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Ribosomal_L11_N PF03946.14 CEH18722.1 - 0.039 13.8 0.2 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain AMP-binding PF00501.28 CEH18723.1 - 8e-65 219.1 0.0 1e-64 218.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEH18723.1 - 1.1e-09 39.1 0.2 5.1e-09 37.0 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ELO PF01151.18 CEH18725.1 - 4e-55 187.0 14.8 4.9e-55 186.8 14.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2236 PF09995.9 CEH18725.1 - 0.064 13.5 0.0 0.16 12.2 0.0 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) CX9C PF16860.5 CEH18728.1 - 0.1 12.6 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF4532 PF15046.6 CEH18730.1 - 0.0052 16.0 0.5 0.0059 15.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4532) bZIP_1 PF00170.21 CEH18731.1 - 3.9e-07 30.1 7.1 1.4e-06 28.3 7.1 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CEH18731.1 - 3.1e-05 24.0 4.1 3.1e-05 24.0 4.1 2.2 1 1 1 2 2 2 2 Basic region leucine zipper RAC_head PF16717.5 CEH18731.1 - 0.00075 20.4 2.1 0.0016 19.4 2.1 1.5 1 0 0 1 1 1 1 Ribosome-associated complex head domain Spc7 PF08317.11 CEH18731.1 - 0.0017 17.3 1.4 0.0025 16.7 1.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein HIGH_NTase1 PF05636.11 CEH18731.1 - 0.0019 17.5 0.1 0.0027 17.0 0.1 1.3 1 0 0 1 1 1 1 HIGH Nucleotidyl Transferase DUF812 PF05667.11 CEH18731.1 - 0.0057 15.6 0.9 0.0066 15.4 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) KLRAQ PF10205.9 CEH18731.1 - 0.0065 16.7 2.0 0.015 15.5 2.0 1.6 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein CASP_C PF08172.12 CEH18731.1 - 0.015 14.6 1.9 0.031 13.6 1.9 1.6 1 0 0 1 1 1 0 CASP C terminal Yuri_gagarin PF15934.5 CEH18731.1 - 0.084 12.7 3.1 0.13 12.1 3.1 1.2 1 0 0 1 1 1 0 Yuri gagarin PKcGMP_CC PF16808.5 CEH18731.1 - 0.093 12.6 0.9 0.26 11.2 0.9 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_Maf PF03131.17 CEH18731.1 - 0.12 12.9 4.1 0.29 11.7 4.1 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor YabA PF06156.13 CEH18731.1 - 0.63 10.7 1.9 1.1 9.9 1.3 1.6 1 1 0 1 1 1 0 Initiation control protein YabA Macoilin PF09726.9 CEH18731.1 - 2.7 6.5 6.4 3.5 6.1 6.4 1.3 1 0 0 1 1 1 0 Macoilin family TTL PF03133.15 CEH18732.1 - 1.3e-43 149.2 0.0 3.1e-43 148.0 0.0 1.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CEH18732.1 - 0.17 11.1 0.0 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 YheC/D like ATP-grasp PhyH PF05721.13 CEH18733.1 - 1.2e-08 35.5 0.0 3.4e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) ATP-synt_E PF05680.12 CEH18734.1 - 9.1e-13 48.4 0.1 9.1e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain MAGE_N PF12440.8 CEH18734.1 - 0.041 14.6 0.5 0.045 14.4 0.5 1.1 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal SspP PF08179.12 CEH18735.1 - 0.13 12.7 0.0 23 5.5 0.0 2.5 2 0 0 2 2 2 0 Small acid-soluble spore protein P family Metallophos PF00149.28 CEH18736.1 - 2.1e-36 126.4 0.1 3.5e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEH18736.1 - 1.1e-16 60.9 0.0 2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Mntp PF02659.15 CEH18738.1 - 0.034 13.9 5.0 0.064 13.0 5.0 1.4 1 0 0 1 1 1 0 Putative manganese efflux pump Nitrate_red_gam PF02665.14 CEH18738.1 - 0.059 12.9 7.5 1.3 8.6 0.3 2.3 1 1 1 2 2 2 0 Nitrate reductase gamma subunit Cupin_8 PF13621.6 CEH18739.1 - 8.6e-30 104.3 0.0 1e-29 104.0 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CEH18739.1 - 1.5e-06 27.9 0.1 3.6e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 CEH18739.1 - 0.00019 21.9 0.0 0.00061 20.2 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 CEH18739.1 - 0.042 13.6 0.2 0.094 12.4 0.0 1.6 2 0 0 2 2 2 0 Cupin domain Cupin_1 PF00190.22 CEH18739.1 - 0.063 12.9 0.0 0.08 12.5 0.0 1.3 1 1 0 1 1 1 0 Cupin DnaJ PF00226.31 CEH18741.1 - 1.8e-11 43.9 2.3 4.5e-11 42.7 2.3 1.7 1 1 0 1 1 1 1 DnaJ domain DivIC PF04977.15 CEH18741.1 - 1.9 8.3 5.5 0.3 10.9 1.6 1.6 2 0 0 2 2 2 0 Septum formation initiator DnaJ PF00226.31 CEH18742.1 - 3.9e-15 55.7 0.0 9.3e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Rrn6 PF10214.9 CEH18742.1 - 1.8 6.9 7.9 2.4 6.5 7.9 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Spt5_N PF11942.8 CEH18742.1 - 3.7 8.6 15.1 8.3 7.5 15.1 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal EMP24_GP25L PF01105.24 CEH18743.1 - 5.9e-37 127.4 0.0 6.8e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Trimer_CC PF08954.11 CEH18743.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Trimerisation motif TRPM_tetra PF16519.5 CEH18743.1 - 0.074 13.2 0.1 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Tetramerisation domain of TRPM adh_short PF00106.25 CEH18744.1 - 3.1e-39 134.5 0.1 3.7e-39 134.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH18744.1 - 5.2e-28 98.2 0.0 5.6e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH18744.1 - 3.9e-16 59.5 0.2 5.5e-16 59.0 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CEH18744.1 - 0.0016 17.9 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 CEH18744.1 - 0.0031 17.0 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 CEH18744.1 - 0.083 12.8 0.4 0.57 10.1 0.0 2.1 1 1 1 2 2 2 0 YjeF-related protein N-terminus Eno-Rase_NADH_b PF12242.8 CEH18744.1 - 0.14 11.9 0.2 0.36 10.6 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Noc2 PF03715.13 CEH18745.1 - 4.8e-116 387.2 0.2 1.2e-115 385.9 0.0 1.7 2 0 0 2 2 2 1 Noc2p family TFIIA PF03153.13 CEH18745.1 - 5.1 7.0 35.9 0.025 14.6 8.6 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Amino_oxidase PF01593.24 CEH18746.1 - 4.1e-09 36.2 0.0 5.8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEH18746.1 - 1.3e-07 31.8 0.2 2.3e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEH18746.1 - 1.1e-05 24.8 0.2 0.032 13.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEH18746.1 - 0.0098 15.9 0.1 0.27 11.2 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CEH18746.1 - 0.031 13.5 0.3 0.23 10.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEH18746.1 - 0.057 13.0 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CEH18746.1 - 0.14 10.8 0.2 0.38 9.4 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 CEH18746.1 - 0.16 11.2 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain VbhA PF18495.1 CEH18746.1 - 0.2 11.6 1.2 4 7.4 1.0 2.7 2 0 0 2 2 2 0 Antitoxin VbhA MTP18 PF10558.9 CEH18749.1 - 4.5e-63 212.3 0.1 7.5e-63 211.5 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Solute_trans_a PF03619.16 CEH18750.1 - 2e-72 243.9 6.4 2.4e-72 243.6 6.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GREB1 PF15782.5 CEH18750.1 - 4.6 4.2 4.2 5.5 4.0 4.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HsbA PF12296.8 CEH18752.1 - 7.9e-21 74.7 9.5 7.9e-21 74.7 9.5 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A UPRTase PF14681.6 CEH18754.1 - 1.2e-44 152.2 0.1 1.2e-41 142.5 0.0 2.1 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase Phosphoesterase PF04185.14 CEH18755.1 - 1.3e-25 90.4 1.8 2.3e-25 89.6 1.8 1.4 1 1 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.15 CEH18756.1 - 2.6e-39 133.9 2.7 4.8e-38 129.8 0.4 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CEH18756.1 - 1.1e-29 102.9 2.6 3.5e-26 91.6 0.1 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 CEH18756.1 - 1.4e-26 93.5 0.0 3.8e-26 92.1 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase N_BRCA1_IG PF16158.5 CEH18756.1 - 0.059 14.1 0.0 0.28 11.9 0.0 2.1 2 0 0 2 2 2 0 Ig-like domain from next to BRCA1 gene HAD PF12710.7 CEH18757.1 - 4.3e-18 66.4 0.0 5.5e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CEH18757.1 - 3.2e-07 30.1 4.3 4.2e-06 26.5 2.6 2.5 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 CEH18757.1 - 6e-05 22.5 0.7 0.00015 21.3 0.3 1.7 2 0 0 2 2 2 1 Putative Phosphatase PhoU_div PF01865.16 CEH18757.1 - 0.032 13.6 0.4 0.49 9.7 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF47 Hydrolase PF00702.26 CEH18757.1 - 0.19 12.0 1.5 52 4.0 0.0 3.0 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase CSN8_PSD8_EIF3K PF10075.9 CEH18758.1 - 4.8e-22 78.5 0.0 3.3e-21 75.8 0.0 2.1 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Fungal_trans PF04082.18 CEH18760.1 - 1.4e-17 63.6 0.0 2.8e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEH18760.1 - 1.1e-09 38.3 9.3 1.8e-09 37.5 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Usp PF00582.26 CEH18761.1 - 3.7e-20 72.9 0.1 3.7e-20 72.9 0.1 2.9 3 0 0 3 3 3 1 Universal stress protein family Cellulase PF00150.18 CEH18762.1 - 5.2e-18 65.5 0.2 7.8e-18 64.9 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DEAD PF00270.29 CEH18763.1 - 6.8e-16 58.5 0.0 1.6e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH18763.1 - 0.00052 20.3 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BRO1 PF03097.18 CEH18764.1 - 1.9e-109 366.0 0.0 3.8e-85 286.1 0.0 2.6 2 1 1 3 3 3 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CEH18764.1 - 7.2e-68 229.0 11.0 7.2e-68 229.0 11.0 1.9 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Med5 PF08689.10 CEH18765.1 - 1.6e-22 79.3 0.0 2.4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit Med5 PK PF00224.21 CEH18766.1 - 5.6e-167 554.9 13.2 1.2e-100 336.8 3.8 2.1 1 1 1 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 CEH18766.1 - 1.3e-35 122.1 0.0 3.3e-35 120.8 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CEH18766.1 - 2e-05 23.9 0.9 0.011 14.9 0.1 2.8 1 1 2 3 3 3 2 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 CEH18766.1 - 0.031 13.3 0.3 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF218 PF02698.17 CEH18766.1 - 0.076 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 DUF218 domain APG9 PF04109.16 CEH18767.1 - 2e-196 653.7 4.3 2.4e-196 653.4 4.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 SURF4 PF02077.15 CEH18768.1 - 1.6e-95 319.7 2.9 1.9e-95 319.5 2.9 1.0 1 0 0 1 1 1 1 SURF4 family DUF5562 PF17717.1 CEH18768.1 - 0.0074 16.3 2.3 0.029 14.4 0.3 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5562) RRM_1 PF00076.22 CEH18769.1 - 1e-21 76.5 0.0 1.4e-12 47.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GMC_oxred_N PF00732.19 CEH18770.1 - 1.3e-65 221.7 0.1 1.8e-65 221.3 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEH18770.1 - 2.8e-30 105.8 0.0 8.7e-30 104.1 0.0 1.9 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CEH18770.1 - 2.8e-05 24.3 0.1 8.2e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEH18770.1 - 0.00033 20.0 0.2 0.0018 17.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CEH18770.1 - 0.00076 18.6 4.5 0.00093 18.3 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CEH18770.1 - 0.0017 17.5 6.5 0.0054 15.9 1.5 2.5 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 CEH18770.1 - 0.0022 17.6 0.1 0.0022 17.6 0.1 2.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 CEH18770.1 - 0.0048 16.2 0.2 0.0089 15.3 0.2 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 CEH18770.1 - 0.12 12.3 1.8 0.64 10.0 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CEH18770.1 - 0.39 9.9 3.8 1.5 8.0 1.3 2.6 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M16_M PF16187.5 CEH18771.1 - 4.5e-95 318.1 0.0 7.3e-95 317.5 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CEH18771.1 - 3.8e-41 140.5 0.2 1.4e-40 138.7 0.1 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CEH18771.1 - 2.9e-30 105.6 0.0 1.5e-19 70.8 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain PXA PF02194.15 CEH18772.1 - 5.2e-34 117.8 0.0 1.8e-33 116.1 0.0 2.0 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 CEH18772.1 - 1.1e-23 83.9 3.3 8e-23 81.2 0.1 3.8 5 0 0 5 5 5 1 Sorting nexin C terminal PX PF00787.24 CEH18772.1 - 6.8e-12 45.4 0.0 1.4e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 PX domain LytR_cpsA_psr PF03816.14 CEH18772.1 - 0.0026 17.9 0.0 0.0079 16.4 0.0 1.8 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain RGS PF00615.19 CEH18772.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Regulator of G protein signaling domain ADH_N PF08240.12 CEH18773.1 - 2.1e-18 66.2 0.7 4.3e-18 65.2 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEH18773.1 - 1.5e-07 31.5 0.0 2.4e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 CEH18773.1 - 0.00051 19.4 0.0 0.00085 18.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 CEH18773.1 - 0.014 14.8 0.0 0.06 12.7 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEH18773.1 - 0.019 14.3 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 CEH18773.1 - 0.026 15.0 0.0 0.038 14.5 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox PF00070.27 CEH18773.1 - 0.032 14.8 0.0 0.31 11.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 CEH18773.1 - 0.15 11.4 1.8 3.1 7.1 0.6 2.3 2 0 0 2 2 2 0 ThiF family Cyclin_N PF00134.23 CEH18775.1 - 1.5e-15 57.1 0.1 2.5e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CEH18775.1 - 1.1e-09 38.8 0.1 1.7e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin CCDC23 PF15674.5 CEH18776.1 - 0.072 13.1 0.2 0.098 12.7 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 Metallophos PF00149.28 CEH18778.1 - 1.3e-13 51.9 3.6 2.6e-13 50.9 3.6 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEH18778.1 - 1.7e-06 28.3 3.1 9.6e-05 22.6 3.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Kinesin PF00225.23 CEH18779.1 - 3.2e-107 358.3 0.2 8.6e-107 356.9 0.2 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEH18779.1 - 5.8e-24 84.7 0.0 2e-23 83.0 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding ApoO PF09769.9 CEH18779.1 - 3.6 7.5 7.8 1.4 8.9 0.1 3.9 2 1 0 3 3 3 0 Apolipoprotein O CRF PF00473.17 CEH18779.1 - 4.7 7.4 6.0 3.5 7.8 1.4 3.3 3 0 0 3 3 3 0 Corticotropin-releasing factor family G_glu_transpept PF01019.21 CEH18781.1 - 3.7e-127 425.2 0.5 4.5e-127 424.9 0.5 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase IBR PF01485.21 CEH18782.1 - 4.4e-20 71.7 44.2 1.4e-11 44.4 3.2 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CEH18782.1 - 0.00014 21.7 1.0 0.00014 21.7 1.0 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEH18782.1 - 0.00061 19.8 1.3 0.00061 19.8 1.3 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 CEH18782.1 - 0.00094 19.5 0.8 0.00094 19.5 0.8 4.0 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 CEH18782.1 - 0.00098 18.9 1.8 0.00098 18.9 1.8 4.8 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEH18782.1 - 0.071 13.3 0.4 0.071 13.3 0.4 4.4 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING DUF4965 PF16335.5 CEH18783.1 - 2.3e-70 235.8 0.1 3.8e-70 235.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 CEH18783.1 - 5.9e-54 183.0 0.1 5.9e-54 183.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 CEH18783.1 - 3e-47 161.3 0.2 6.5e-47 160.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) ZIP4_domain PF18292.1 CEH18783.1 - 0.002 18.0 0.2 0.005 16.8 0.2 1.6 1 0 0 1 1 1 1 Zinc transporter ZIP4 domain Ctr PF04145.15 CEH18784.1 - 5.2e-27 95.3 0.0 6.6e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF1286 PF06939.11 CEH18784.1 - 0.04 14.2 1.4 0.095 13.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1286) F-box PF00646.33 CEH18785.1 - 0.00028 20.7 0.8 0.0018 18.1 0.2 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CEH18785.1 - 0.014 15.3 0.2 0.044 13.7 0.2 1.9 1 0 0 1 1 1 0 F-box-like p450 PF00067.22 CEH18787.1 - 6.8e-58 196.5 0.0 1.1e-57 195.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Sec39 PF08314.11 CEH18788.1 - 1.8e-38 132.6 0.0 2.9e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 GAIN PF16489.5 CEH18788.1 - 0.035 13.5 0.3 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 GPCR-Autoproteolysis INducing (GAIN) domain VASt PF16016.5 CEH18790.1 - 2.6e-38 131.8 0.0 4e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CEH18790.1 - 1.9e-22 79.3 0.0 3.2e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Matrilin_ccoil PF10393.9 CEH18790.1 - 0.3 11.0 0.5 0.52 10.2 0.5 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin MFS_1 PF07690.16 CEH18791.1 - 2e-29 102.7 38.3 3e-18 65.9 8.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH18791.1 - 2e-19 69.8 13.2 1.2e-18 67.2 0.2 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter Rhomboid_SP PF12595.8 CEH18792.1 - 0.097 12.0 0.2 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 Rhomboid serine protease RRM_1 PF00076.22 CEH18793.1 - 4.4e-38 128.9 1.1 7.2e-22 77.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CEH18793.1 - 2.1e-10 41.5 1.5 2.1e-10 41.5 1.5 3.6 3 1 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 CEH18793.1 - 2.1e-06 27.5 0.0 0.0023 17.7 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CEH18793.1 - 0.00012 21.7 0.0 0.0024 17.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CEH18793.1 - 0.11 12.6 0.1 0.11 12.6 0.1 3.0 3 0 0 3 3 3 0 Limkain b1 RRM_8 PF11835.8 CEH18793.1 - 0.15 12.3 0.0 0.64 10.3 0.0 2.0 2 0 0 2 2 2 0 RRM-like domain Prefoldin_2 PF01920.20 CEH18794.1 - 1.4e-19 70.0 5.3 1.6e-19 69.8 5.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit EzrA PF06160.12 CEH18794.1 - 0.0051 15.1 5.2 0.34 9.0 0.3 2.0 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.8 CEH18794.1 - 0.0071 16.6 3.4 0.013 15.7 3.3 1.4 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF812 PF05667.11 CEH18794.1 - 0.0087 15.0 2.8 0.013 14.4 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FlaC_arch PF05377.11 CEH18794.1 - 0.018 15.5 1.8 0.054 13.9 0.2 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.17 CEH18794.1 - 0.023 14.6 5.7 0.44 10.5 1.0 2.2 1 1 1 2 2 2 0 Prefoldin subunit Rx_N PF18052.1 CEH18794.1 - 0.036 14.3 0.2 0.72 10.2 0.0 2.1 2 0 0 2 2 2 0 Rx N-terminal domain Dynein_AAA_lid PF17852.1 CEH18794.1 - 0.049 13.7 0.1 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain DASH_Dad3 PF08656.10 CEH18794.1 - 0.06 13.4 2.1 0.11 12.6 0.1 2.1 2 1 0 2 2 2 0 DASH complex subunit Dad3 CENP-F_leu_zip PF10473.9 CEH18794.1 - 0.073 13.1 5.4 0.73 9.9 0.2 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1394 PF07159.12 CEH18794.1 - 0.099 11.9 1.2 0.14 11.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) Helo_like_N PF17111.5 CEH18794.1 - 0.16 11.3 2.6 1.7 8.0 0.4 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins YabA PF06156.13 CEH18794.1 - 0.19 12.4 3.9 9.6 6.9 0.5 2.1 2 0 0 2 2 2 0 Initiation control protein YabA YscO PF07321.12 CEH18794.1 - 0.36 10.8 9.5 0.15 12.0 2.9 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO ATG16 PF08614.11 CEH18794.1 - 0.38 10.9 8.0 2.5 8.3 0.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IFT57 PF10498.9 CEH18794.1 - 0.46 9.4 5.3 1.7 7.6 0.9 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 CEH18794.1 - 0.87 9.6 10.7 0.58 10.2 1.3 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 CEH18794.1 - 1.3 9.3 6.1 1.3 9.2 0.5 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 CEH18794.1 - 2.4 8.7 11.2 3.3 8.2 1.3 2.0 1 1 0 2 2 2 0 Apg6 coiled-coil region bVLRF1 PF18826.1 CEH18795.1 - 2.6e-47 160.4 0.0 5.2e-47 159.4 0.0 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 CEH18795.1 - 0.0062 16.8 0.0 0.044 14.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CEH18795.1 - 0.016 15.6 0.0 0.046 14.2 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 CEH18795.1 - 0.026 15.1 0.0 0.083 13.5 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat MecA PF05389.12 CEH18795.1 - 0.031 13.9 0.4 0.068 12.8 0.0 1.7 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Ank_2 PF12796.7 CEH18795.1 - 0.11 13.1 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEH18795.1 - 0.18 12.4 0.0 0.44 11.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Dopey_N PF04118.14 CEH18796.1 - 1.2e-109 366.2 0.0 2.4e-109 365.2 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal Velvet PF11754.8 CEH18798.1 - 9.7e-18 65.0 8.1 7.3e-13 49.0 0.3 2.8 2 1 0 3 3 3 2 Velvet factor Prenyltrans PF00432.21 CEH18799.1 - 1e-26 92.4 11.3 3.8e-08 32.9 0.2 5.9 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CEH18799.1 - 0.00019 20.6 0.0 0.04 13.0 0.0 2.3 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain MutS_V PF00488.21 CEH18800.1 - 4.1e-50 170.4 0.0 9.1e-50 169.3 0.0 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CEH18800.1 - 2.1e-28 99.9 4.3 2.1e-28 99.9 4.3 2.1 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CEH18800.1 - 1.3e-07 32.0 0.0 0.00032 21.0 0.0 2.6 2 0 0 2 2 2 2 MutS domain II MutS_IV PF05190.18 CEH18800.1 - 0.0036 17.6 0.0 0.0085 16.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.6 CEH18800.1 - 0.004 17.2 0.1 0.022 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CEH18800.1 - 0.028 14.7 0.1 0.26 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CEH18800.1 - 0.084 13.4 0.2 0.24 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CEH18800.1 - 0.09 12.9 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CEH18800.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain p450 PF00067.22 CEH18801.1 - 2e-60 204.8 0.0 3.5e-41 141.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Kelch_4 PF13418.6 CEH18802.1 - 5e-17 61.6 14.0 9.8e-08 31.9 0.0 5.7 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CEH18802.1 - 7.9e-07 28.9 4.2 0.011 15.7 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CEH18802.1 - 2.2e-05 24.6 30.8 0.13 12.6 0.3 7.9 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CEH18802.1 - 9.9e-05 22.5 6.9 0.38 11.1 0.0 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 CEH18802.1 - 0.0021 17.6 4.9 4.2 7.0 0.6 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CEH18802.1 - 0.053 13.5 3.1 21 5.3 0.0 4.4 4 0 0 4 4 4 0 Kelch motif PhoLip_ATPase_C PF16212.5 CEH18803.1 - 1.3e-68 231.4 28.6 1.3e-68 231.4 28.6 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEH18803.1 - 2.8e-22 78.2 4.7 7.8e-22 76.7 4.7 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CEH18803.1 - 3.2e-12 46.4 0.0 3.6e-11 43.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEH18803.1 - 6.3e-11 43.0 2.0 4.4e-06 27.1 1.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEH18803.1 - 7.5e-06 25.6 0.1 4.2e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEH18803.1 - 0.0004 20.2 0.4 0.0077 16.0 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FliN_N PF16973.5 CEH18807.1 - 0.016 15.0 0.1 0.016 15.0 0.1 1.8 2 0 0 2 2 2 0 Flagellar motor switch protein FliN N-terminal DUF802 PF05650.11 CEH18807.1 - 0.055 14.0 0.4 0.21 12.1 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF802) RhoGAP PF00620.27 CEH18808.1 - 6.1e-38 130.0 0.0 1.1e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 CEH18808.1 - 0.0015 18.8 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain AAA_3 PF07726.11 CEH18808.1 - 0.033 14.0 0.0 0.09 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) BAR_3 PF16746.5 CEH18810.1 - 0.0097 15.6 1.0 0.021 14.5 1.0 1.5 1 0 0 1 1 1 1 BAR domain of APPL family Sigma70_ner PF04546.13 CEH18810.1 - 0.022 14.7 1.5 0.35 10.7 1.5 2.3 1 1 0 1 1 1 0 Sigma-70, non-essential region SSF PF00474.17 CEH18811.1 - 8.2e-11 41.4 20.1 1.1e-10 41.0 18.3 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family Spore_permease PF03845.13 CEH18811.1 - 0.00012 21.0 5.9 0.00031 19.7 5.9 1.6 1 0 0 1 1 1 1 Spore germination protein adh_short_C2 PF13561.6 CEH18812.1 - 1.2e-37 129.7 0.0 1.8e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH18812.1 - 1.2e-25 90.1 0.0 1.7e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH18812.1 - 1.1e-06 28.7 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Wax2_C PF12076.8 CEH18812.1 - 0.044 13.5 0.0 10 5.8 0.0 2.1 2 0 0 2 2 2 0 WAX2 C-terminal domain THF_DHG_CYH_C PF02882.19 CEH18812.1 - 0.079 12.3 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 CEH18812.1 - 0.084 12.3 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Oxidored_nitro PF00148.19 CEH18812.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase NMO PF03060.15 CEH18813.1 - 3.5e-53 181.1 0.4 5.1e-53 180.6 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CEH18813.1 - 1.7e-11 43.8 0.7 1.7e-11 43.8 0.7 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CEH18813.1 - 0.00038 19.6 1.0 0.00059 19.0 1.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PNP_phzG_C PF10590.9 CEH18814.1 - 1.9e-16 59.8 1.0 3.7e-16 58.9 1.0 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 CEH18814.1 - 2.2e-15 56.6 0.0 4.2e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cellulase PF00150.18 CEH18815.1 - 8.2e-19 68.1 2.1 1.5e-18 67.2 2.1 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glycos_transf_1 PF00534.20 CEH18816.1 - 1.4e-30 106.1 0.0 3.6e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CEH18816.1 - 1.9e-24 86.6 0.0 3.2e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CEH18816.1 - 1.9e-24 86.6 0.0 3.9e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CEH18816.1 - 2.7e-14 53.9 1.1 1.1e-13 52.0 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CEH18816.1 - 0.0022 18.3 4.2 0.26 11.7 0.0 3.4 2 1 1 3 3 3 1 Glycosyl transferases group 1 DUF2471 PF10616.9 CEH18816.1 - 0.025 15.1 0.4 0.052 14.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2471) REV1_C PF16727.5 CEH18816.1 - 0.075 13.4 0.2 0.23 11.9 0.2 1.7 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Ank_2 PF12796.7 CEH18817.1 - 5.9e-23 81.3 0.0 1.2e-15 57.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEH18817.1 - 3.4e-19 68.9 5.1 2.1e-10 40.9 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEH18817.1 - 4.8e-13 48.0 1.5 8.1e-05 22.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CEH18817.1 - 5.5e-13 48.7 6.0 1.3e-05 25.4 0.3 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CEH18817.1 - 4.2e-10 39.7 5.7 8.8e-05 22.7 0.1 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) TFA2_Winged_2 PF18121.1 CEH18818.1 - 1.3e-16 60.0 0.0 3.1e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 CEH18818.1 - 9.3e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 TFIIE beta subunit core domain FoP_duplication PF13865.6 CEH18818.1 - 1.2 9.7 4.9 2.5 8.7 4.9 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Rot1 PF10681.9 CEH18819.1 - 5e-45 153.6 7.3 5.2e-45 153.5 3.9 2.2 2 1 0 2 2 2 1 Chaperone for protein-folding within the ER, fungal Ribosomal_S21 PF01165.20 CEH18820.1 - 4.1e-09 36.0 2.8 7.6e-09 35.2 2.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 DUF5523 PF17661.1 CEH18821.1 - 0.059 13.0 5.4 0.066 12.9 5.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF2457 PF10446.9 CEH18821.1 - 0.083 12.0 19.4 0.085 12.0 19.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 CEH18821.1 - 0.43 9.9 16.3 0.48 9.7 16.3 1.1 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 CEH18821.1 - 0.54 10.1 17.0 0.69 9.8 17.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 CEH18821.1 - 0.63 8.1 24.9 0.7 7.9 24.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 CEH18821.1 - 0.74 9.8 7.7 0.92 9.5 7.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Astro_capsid_p PF12226.8 CEH18821.1 - 1.1 8.4 15.2 1.2 8.2 15.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 CEH18821.1 - 1.5 6.9 18.3 1.5 6.9 18.3 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 CEH18821.1 - 2.3 7.4 18.4 2.6 7.3 18.4 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 CEH18821.1 - 2.4 6.3 12.3 2.5 6.3 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 CEH18821.1 - 3.2 7.1 15.9 3.3 7.0 15.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 CEH18821.1 - 3.4 7.0 19.0 3.8 6.8 19.0 1.1 1 0 0 1 1 1 0 SDA1 GCIP PF13324.6 CEH18821.1 - 3.5 7.2 9.8 3.8 7.0 9.8 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Zip PF02535.22 CEH18821.1 - 5.6 6.1 6.0 6.4 5.9 6.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter PPP4R2 PF09184.11 CEH18821.1 - 7.6 6.0 18.5 9 5.8 18.5 1.1 1 0 0 1 1 1 0 PPP4R2 Ebp2 PF05890.12 CEH18822.1 - 6.2e-69 232.5 3.2 7.2e-69 232.3 3.2 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 HalX PF08663.10 CEH18822.1 - 0.042 14.2 0.6 0.042 14.2 0.6 2.3 3 0 0 3 3 3 0 HalX domain Cdh1_DBD_1 PF18196.1 CEH18822.1 - 0.51 10.7 6.4 0.82 10.0 6.4 1.3 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 NAT PF04768.13 CEH18823.1 - 3e-30 105.1 0.0 8e-20 71.2 0.0 2.2 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase CdiA_C_tRNase PF18664.1 CEH18823.1 - 0.08 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain AA_kinase PF00696.28 CEH18824.1 - 0.12 12.0 0.3 0.17 11.5 0.3 1.5 1 1 0 1 1 1 0 Amino acid kinase family GRAB PF10375.9 CEH18825.1 - 1.4e-07 31.1 1.7 1.4e-07 31.1 1.7 2.4 2 0 0 2 2 2 1 GRIP-related Arf-binding domain GRIP PF01465.20 CEH18825.1 - 5.9e-05 22.9 0.2 0.0002 21.2 0.2 1.9 1 0 0 1 1 1 1 GRIP domain SlyX PF04102.12 CEH18825.1 - 0.008 16.8 2.0 0.008 16.8 2.0 4.3 3 1 1 4 4 4 1 SlyX Holin_BhlA PF10960.8 CEH18825.1 - 0.11 12.4 10.4 2.3 8.2 0.1 3.6 2 2 1 3 3 3 0 BhlA holin family MPS2 PF17060.5 CEH18825.1 - 0.26 10.5 12.9 0.093 12.0 3.4 2.2 2 0 0 2 2 2 0 Monopolar spindle protein 2 SLATT_5 PF18160.1 CEH18825.1 - 0.32 10.3 2.7 0.38 10.0 0.8 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Spc42p PF11544.8 CEH18825.1 - 0.48 10.5 7.6 0.22 11.5 1.3 3.0 2 1 0 2 2 2 0 Spindle pole body component Spc42p Baculo_PEP_C PF04513.12 CEH18825.1 - 1 9.4 5.2 0.66 10.0 0.9 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CEH18825.1 - 3.8 7.6 7.4 1.1 9.3 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 CEH18825.1 - 8.4 6.6 18.4 1e+02 3.1 4.1 2.6 1 1 1 2 2 2 0 Zinc finger-containing protein TPR_2 PF07719.17 CEH18826.1 - 0.00016 21.6 1.6 13 6.2 1.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEH18826.1 - 0.006 17.3 11.5 0.15 13.0 0.1 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEH18826.1 - 0.024 15.3 0.0 0.024 15.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEH18826.1 - 0.044 13.9 2.8 0.96 9.6 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEH18826.1 - 0.061 13.8 17.0 0.56 10.8 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEH18826.1 - 0.12 12.5 1.6 2 8.7 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEH18826.1 - 0.18 12.5 2.7 30 5.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Metallophos PF00149.28 CEH18827.1 - 1.1e-39 137.1 0.1 1.5e-39 136.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEH18827.1 - 1.4e-19 70.3 0.5 2.7e-19 69.3 0.3 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain TAL_FSA PF00923.19 CEH18828.1 - 9.4e-94 314.0 0.4 1.1e-93 313.8 0.4 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase EI24 PF07264.11 CEH18829.1 - 2.3e-09 37.7 2.5 3.5e-09 37.1 2.5 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ribonucleas_3_3 PF14622.6 CEH18830.1 - 3.1e-24 85.6 0.1 5.1e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CEH18830.1 - 0.022 15.4 0.0 0.053 14.2 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease III domain zf-C2H2 PF00096.26 CEH18831.1 - 1.8e-09 37.5 14.1 1.3e-05 25.4 3.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEH18831.1 - 0.0002 21.9 11.9 0.098 13.5 3.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEH18831.1 - 0.00039 20.7 3.4 0.00039 20.7 3.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 CEH18831.1 - 0.0026 18.0 0.6 0.0081 16.4 0.6 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 CEH18831.1 - 0.011 16.4 4.4 0.14 12.8 0.4 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 CEH18831.1 - 1.4 9.0 7.1 2.6 8.2 2.2 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 CEH18831.1 - 9.8 6.0 7.5 12 5.8 1.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Mo25 PF08569.11 CEH18833.1 - 5.9e-134 446.6 6.7 6.9e-134 446.3 6.7 1.0 1 0 0 1 1 1 1 Mo25-like DUF4479 PF14794.6 CEH18833.1 - 0.042 13.7 1.5 0.68 9.8 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4479) Spore_GerQ PF09671.10 CEH18833.1 - 0.065 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) HEAT_2 PF13646.6 CEH18833.1 - 0.094 13.1 0.0 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats CH PF00307.31 CEH18834.1 - 7.9e-77 254.5 0.0 1.9e-19 69.8 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 CEH18834.1 - 7.7e-07 29.5 0.2 1.6e-05 25.3 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.8 CEH18834.1 - 6.6e-06 25.9 0.0 0.32 10.9 0.0 3.5 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.6 CEH18834.1 - 0.00098 18.9 0.4 7.8 6.7 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CEH18834.1 - 0.0023 17.4 1.2 0.033 13.7 0.0 3.1 3 0 0 3 3 3 1 EF hand CH_2 PF06294.11 CEH18834.1 - 0.062 13.4 0.0 14 5.9 0.0 2.9 3 0 0 3 3 3 0 CH-like domain in sperm protein EF-hand_9 PF14658.6 CEH18834.1 - 0.17 12.2 0.5 2.4 8.5 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain Sec2p PF06428.11 CEH18835.1 - 1.2e-16 60.5 6.9 1.2e-16 60.5 6.9 2.9 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p SF-assemblin PF06705.11 CEH18835.1 - 0.5 9.7 10.6 0.089 12.1 4.5 2.0 1 1 1 2 2 2 0 SF-assemblin/beta giardin FlxA PF14282.6 CEH18835.1 - 1.8 8.6 7.2 0.35 10.9 1.9 2.7 2 0 0 2 2 2 0 FlxA-like protein COG5 PF10392.9 CEH18835.1 - 2.2 8.5 6.4 4.8 7.4 1.2 2.6 1 1 1 2 2 2 0 Golgi transport complex subunit 5 AMP-binding PF00501.28 CEH18836.1 - 5.5e-94 315.2 0.1 6.6e-94 314.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEH18836.1 - 3.6e-27 95.2 0.5 4.5e-25 88.4 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CEH18836.1 - 5.8e-18 64.6 1.8 1.4e-17 63.3 1.2 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 CEH18836.1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) DEAD PF00270.29 CEH18837.1 - 7.7e-43 146.3 0.3 1.3e-42 145.5 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH18837.1 - 2e-33 115.1 0.2 1.1e-32 112.6 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEH18837.1 - 0.0002 21.4 0.0 0.00042 20.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CEH18837.1 - 0.00066 20.0 0.0 0.035 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEH18837.1 - 0.0091 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 CEH18837.1 - 0.017 13.9 0.1 0.56 8.9 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_RecD PF05127.14 CEH18837.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Helicase Ribul_P_3_epim PF00834.19 CEH18838.1 - 3.6e-65 219.1 0.1 4.4e-65 218.8 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 CEH18838.1 - 0.0041 16.9 0.0 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 CEH18838.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family LSM PF01423.22 CEH18839.1 - 5.2e-18 64.5 0.6 6.4e-18 64.2 0.6 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 CEH18839.1 - 0.025 14.5 0.2 0.044 13.7 0.2 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain SM-ATX PF14438.6 CEH18839.1 - 0.036 14.2 0.2 0.043 13.9 0.2 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF2642 PF10842.8 CEH18839.1 - 0.061 13.2 0.3 0.72 9.7 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2642) Gemin7 PF11095.8 CEH18839.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) WD40 PF00400.32 CEH18840.1 - 1.5e-41 139.6 24.7 1.8e-07 31.7 0.0 12.5 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.12 CEH18840.1 - 1.4e-20 73.6 0.1 2.3e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CEH18840.1 - 1.5e-20 73.3 0.0 0.00066 19.9 0.0 9.4 5 3 6 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEH18840.1 - 9.7e-07 28.0 3.9 1.1 8.1 0.0 6.4 5 2 2 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CEH18840.1 - 0.00024 21.0 0.0 4.2 7.4 0.0 5.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 CEH18840.1 - 0.00056 19.8 0.3 28 4.5 0.0 5.6 5 1 2 8 8 8 0 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.7 CEH18840.1 - 0.00079 19.4 0.2 5.5 6.9 0.0 4.3 4 0 0 4 4 4 1 Transcription factor IIIC subunit delta N-term Nup160 PF11715.8 CEH18840.1 - 0.0013 17.5 0.1 0.21 10.2 0.0 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CEH18840.1 - 0.0021 17.7 0.8 0.17 11.5 0.8 2.6 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.16 CEH18840.1 - 0.015 13.8 0.0 1.3 7.5 0.0 3.0 3 0 0 3 3 3 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 CEH18840.1 - 0.026 13.3 0.0 1.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 CEH18840.1 - 0.18 11.1 0.0 2.2 7.5 0.0 2.6 2 1 1 3 3 3 0 WD40-like domain PI3_PI4_kinase PF00454.27 CEH18841.1 - 6e-28 98.3 0.0 8.5e-19 68.3 0.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CEH18841.1 - 9.8e-21 74.0 0.0 2.2e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Hemerythrin PF01814.23 CEH18842.1 - 2.2e-09 38.0 1.5 2.5e-09 37.8 1.5 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain JAB PF01398.21 CEH18843.1 - 1.6e-16 60.4 0.0 3.3e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 CEH18843.1 - 2.6e-07 30.8 0.0 9.8e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 CEH18843.1 - 0.00053 19.7 0.4 0.002 17.9 0.0 2.2 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain DEAD PF00270.29 CEH18846.1 - 2.7e-44 151.0 0.0 4.9e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH18846.1 - 1.6e-26 92.8 0.0 3.6e-25 88.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CEH18846.1 - 2.9e-18 65.8 0.1 6.1e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 CEH18846.1 - 1.5e-05 24.4 0.0 2.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CEH18846.1 - 0.0084 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SHQ1 PF04925.15 CEH18850.1 - 3.8e-23 82.0 0.0 6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein Ammonium_transp PF00909.21 CEH18851.1 - 6e-86 288.6 27.1 7.6e-86 288.3 27.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MBOAT_2 PF13813.6 CEH18852.1 - 7.9e-08 32.5 0.6 7e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family MscS_TM PF12794.7 CEH18852.1 - 0.026 13.4 0.5 0.026 13.4 0.5 2.1 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 WAC_Acf1_DNA_bd PF10537.9 CEH18856.1 - 5.8e-31 107.0 1.0 1.2e-30 106.0 0.1 2.1 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CEH18856.1 - 3.6e-26 91.5 0.1 3.6e-26 91.5 0.1 3.4 4 0 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 CEH18856.1 - 3.9e-10 39.9 0.0 8.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 CEH18856.1 - 0.0026 17.2 0.0 0.0065 16.0 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Choline_kinase PF01633.20 CEH18857.1 - 2.9e-13 49.9 0.0 8.5e-13 48.4 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CEH18857.1 - 2.3e-05 24.5 4.5 0.15 12.0 0.0 3.0 2 1 0 2 2 2 2 Phosphotransferase enzyme family tRNA_deacylase PF04414.12 CEH18857.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase RRM_1 PF00076.22 CEH18858.1 - 2.1e-08 33.8 0.1 0.0012 18.6 0.0 3.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NCE101 PF11654.8 CEH18859.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Non-classical export protein 1 UPRTase PF14681.6 CEH18860.1 - 2.9e-65 219.6 0.0 3.3e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Aconitase PF00330.20 CEH18861.1 - 2.9e-110 369.4 0.4 2.7e-109 366.2 0.4 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEH18861.1 - 5.5e-21 75.3 0.0 2e-20 73.5 0.0 1.9 1 1 0 1 1 1 1 Aconitase C-terminal domain Anthrax_toxA PF03497.16 CEH18861.1 - 0.021 14.9 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Anthrax toxin LF subunit adh_short PF00106.25 CEH18863.1 - 1.2e-28 99.9 1.5 7.8e-28 97.3 1.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH18863.1 - 1.2e-27 97.0 1.0 1.1e-25 90.5 1.0 2.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH18863.1 - 3.6e-07 30.3 0.5 8.2e-07 29.1 0.5 1.6 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 CEH18863.1 - 0.0055 16.6 0.3 0.0097 15.8 0.3 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus ADH_zinc_N PF00107.26 CEH18863.1 - 0.051 13.6 0.3 0.1 12.6 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 CEH18863.1 - 0.062 12.5 0.2 0.093 11.9 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Suf PF05843.14 CEH18866.1 - 6e-76 256.2 0.2 6e-74 249.7 0.0 3.9 5 1 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CEH18866.1 - 0.0006 20.3 2.5 0.12 12.9 0.1 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CEH18866.1 - 0.0028 16.9 5.0 2.6 7.1 0.0 5.2 4 2 1 5 5 5 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CEH18866.1 - 0.0079 16.9 19.3 0.12 13.2 0.4 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat SPO22 PF08631.10 CEH18866.1 - 0.1 12.1 0.1 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 CEH18866.1 - 0.49 11.1 2.6 6.3 7.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SMC_N PF02463.19 CEH18867.1 - 7.4e-25 87.7 0.0 3.4e-24 85.5 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CEH18867.1 - 2.2e-15 57.7 20.2 2.2e-15 57.7 20.2 5.3 2 2 2 4 4 4 1 AAA domain AAA_15 PF13175.6 CEH18867.1 - 7.8e-12 45.6 0.8 7.8e-12 45.6 0.8 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 CEH18867.1 - 8.9e-06 25.7 4.5 0.038 13.8 0.5 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEH18867.1 - 0.00026 20.7 0.1 0.00054 19.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2996 PF11210.8 CEH18867.1 - 0.029 14.8 0.7 0.15 12.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2996) GA-like PF17573.2 CEH18867.1 - 0.1 12.5 2.0 2.4 8.1 0.6 3.6 3 0 0 3 3 3 0 GA-like domain DUF3584 PF12128.8 CEH18867.1 - 2.4 5.5 84.4 0.022 12.3 38.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) HEAT_EZ PF13513.6 CEH18868.1 - 5.4e-05 23.6 6.9 0.64 10.6 1.6 5.4 4 1 1 5 5 5 3 HEAT-like repeat HEAT PF02985.22 CEH18868.1 - 0.00052 20.1 3.9 1.7 9.1 0.0 5.9 4 0 0 4 4 4 1 HEAT repeat PUL PF08324.11 CEH18868.1 - 0.038 13.2 2.2 0.07 12.4 0.1 2.4 2 1 0 3 3 3 0 PUL domain Vac14_Fab1_bd PF12755.7 CEH18868.1 - 0.12 13.0 0.0 0.37 11.4 0.0 1.8 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region IF4E PF01652.18 CEH18869.1 - 3.4e-45 153.7 0.2 3.4e-35 121.2 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic initiation factor 4E Thioredoxin PF00085.20 CEH18870.1 - 0.2 11.7 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin SNF2_N PF00176.23 CEH18871.1 - 2.6e-42 144.8 0.0 4.6e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEH18871.1 - 8.2e-08 32.6 0.2 1.9e-07 31.4 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 CEH18871.1 - 4.2e-05 23.3 4.1 9.6e-05 22.2 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEH18871.1 - 0.00048 20.0 5.7 0.0012 18.8 5.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEH18871.1 - 0.04 13.8 6.2 0.097 12.5 6.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LAGLIDADG_WhiA PF14527.6 CEH18871.1 - 0.061 13.4 0.3 0.21 11.7 0.3 1.9 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain TFA2_Winged_2 PF18121.1 CEH18871.1 - 0.078 12.7 0.0 1.2 8.8 0.0 2.9 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Prok-RING_4 PF14447.6 CEH18871.1 - 0.42 10.5 5.7 1.2 9.1 5.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEH18871.1 - 0.46 10.5 8.8 1 9.4 8.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CEH18871.1 - 1.3 9.0 13.5 0.038 13.8 6.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 CEH18871.1 - 1.8 8.7 4.6 4.2 7.5 4.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_2 PF13639.6 CEH18871.1 - 3.1 8.2 14.2 0.13 12.7 8.0 2.0 2 0 0 2 2 2 0 Ring finger domain Pkinase PF00069.25 CEH18872.1 - 8e-50 169.6 0.0 1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH18872.1 - 6e-35 120.8 0.0 4.9e-33 114.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEH18872.1 - 7.7e-06 24.9 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEH18872.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CEH18872.1 - 0.036 13.4 0.0 0.43 9.8 0.0 2.3 3 0 0 3 3 3 0 Kinase-like Transketolase_N PF00456.21 CEH18873.1 - 1.5e-146 487.6 0.3 2.3e-146 487.0 0.1 1.4 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CEH18873.1 - 5.4e-43 146.7 0.0 1.3e-42 145.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CEH18873.1 - 6.4e-11 42.2 0.0 1.4e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CEH18873.1 - 0.00018 20.8 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 CEH18873.1 - 0.0011 18.0 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component NAC PF01849.18 CEH18874.1 - 4.4e-22 77.8 0.0 9.2e-22 76.8 0.0 1.6 1 0 0 1 1 1 1 NAC domain T3SSipB PF16535.5 CEH18874.1 - 0.026 15.0 0.2 0.12 12.8 0.0 2.0 2 1 0 2 2 2 0 Type III cell invasion protein SipB SET PF00856.28 CEH18875.1 - 3.6e-18 66.5 3.7 4.1e-18 66.3 0.1 2.8 2 2 0 2 2 2 1 SET domain N-SET PF11764.8 CEH18875.1 - 2.2e-13 50.7 7.3 5e-08 33.2 0.3 3.5 2 1 2 4 4 4 2 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.22 CEH18875.1 - 3.9e-05 23.4 0.0 0.00027 20.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pmp3 PF01679.17 CEH18877.1 - 2.1e-25 88.6 26.0 9.7e-22 76.9 12.5 2.1 2 0 0 2 2 2 2 Proteolipid membrane potential modulator Mg_trans_NIPA PF05653.14 CEH18878.1 - 2e-100 335.7 12.6 2.5e-100 335.4 12.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CEH18878.1 - 0.0027 17.9 5.5 0.0027 17.9 5.5 3.6 4 0 0 4 4 4 2 EamA-like transporter family UCH PF00443.29 CEH18879.1 - 4.8e-05 23.0 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4188 PF13826.6 CEH18881.1 - 4.1e-18 65.8 0.1 5.2e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) MuF_C PF18819.1 CEH18881.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 2 1 0 2 2 2 0 Phage MuF-C-terminal domain Prominin PF05478.11 CEH18882.1 - 0.42 8.5 0.4 0.55 8.1 0.4 1.0 1 0 0 1 1 1 0 Prominin Phage_Gp23 PF10669.9 CEH18882.1 - 2.5 8.5 7.0 3.3 8.1 6.3 1.6 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) HECT_2 PF09814.9 CEH18883.1 - 2.7e-24 85.7 0.3 1.1e-23 83.7 0.3 2.0 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Rubredoxin PF00301.20 CEH18883.1 - 0.037 14.1 0.1 0.094 12.8 0.1 1.7 1 0 0 1 1 1 0 Rubredoxin GoLoco PF02188.17 CEH18883.1 - 0.74 9.4 7.2 0.083 12.4 0.5 2.9 3 0 0 3 3 3 0 GoLoco motif TamB PF04357.13 CEH18885.1 - 0.044 13.0 0.0 0.046 12.9 0.0 1.0 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex YTH PF04146.15 CEH18888.1 - 2.1e-33 115.6 1.4 5.1e-33 114.4 0.1 2.1 2 0 0 2 2 2 1 YT521-B-like domain Beta_elim_lyase PF01212.21 CEH18889.1 - 5.2e-50 170.4 1.1 1.6e-38 132.7 0.0 2.1 2 0 0 2 2 2 2 Beta-eliminating lyase Bac_luciferase PF00296.20 CEH18889.1 - 0.016 14.6 1.5 0.16 11.4 0.5 2.2 1 1 1 2 2 2 0 Luciferase-like monooxygenase Svf1_C PF17187.4 CEH18890.1 - 2.6e-45 154.2 0.0 4.5e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 CEH18890.1 - 8.7e-42 142.9 0.2 1.3e-41 142.4 0.2 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain MS_channel PF00924.18 CEH18891.1 - 2.5e-18 66.4 0.5 4.4e-18 65.6 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel FA_hydroxylase PF04116.13 CEH18891.1 - 0.98 9.8 14.1 0.056 13.8 6.4 2.7 2 1 1 3 3 3 0 Fatty acid hydroxylase superfamily ChAPs PF09295.10 CEH18893.1 - 5.2e-157 522.9 0.0 7.7e-157 522.3 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 CEH18893.1 - 7.1e-12 45.7 1.4 2.2e-05 24.9 0.7 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEH18893.1 - 4e-07 29.6 3.8 0.17 12.0 0.1 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEH18893.1 - 3.2e-06 27.4 1.1 5.1 8.0 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH18893.1 - 5.1e-05 23.4 3.3 0.025 14.8 1.5 4.2 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CEH18893.1 - 0.0027 17.8 2.9 0.66 10.3 0.0 4.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEH18893.1 - 0.0045 16.2 2.5 0.056 12.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEH18893.1 - 0.016 16.0 8.6 21 6.3 0.2 6.0 3 2 4 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEH18893.1 - 0.029 15.0 9.0 0.078 13.6 0.6 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEH18893.1 - 0.24 11.5 1.8 10 6.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEH18893.1 - 2 8.8 5.9 79 3.7 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat NDK PF00334.19 CEH18894.1 - 0.021 14.9 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Nucleoside diphosphate kinase DUF4193 PF13834.6 CEH18894.1 - 0.22 12.0 2.1 0.63 10.6 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) Sporozoite_P67 PF05642.11 CEH18898.1 - 1.1 7.2 3.5 1.6 6.7 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF747 PF05346.11 CEH18899.1 - 5.9e-119 397.3 0.2 7.8e-119 396.9 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Cellulase PF00150.18 CEH18901.1 - 5.3e-15 55.6 0.0 8.1e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mss4 PF04421.13 CEH18902.1 - 2.4e-08 34.0 0.0 8.2e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Mss4 protein Acetyltransf_7 PF13508.7 CEH18902.1 - 3.1e-05 24.3 0.0 5.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEH18902.1 - 3.7e-05 23.9 0.0 0.0004 20.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CEH18902.1 - 0.0028 17.6 0.0 0.0093 15.9 0.0 1.9 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CEH18902.1 - 0.0032 17.4 0.0 0.052 13.5 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Sugarporin_N PF11471.8 CEH18902.1 - 0.096 12.7 2.7 0.92 9.5 0.7 3.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Acetyltransf_15 PF17013.5 CEH18902.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 CEH18902.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PLA2_B PF01735.18 CEH18904.1 - 1.5e-126 422.7 1.2 1.9e-126 422.4 1.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PARP PF00644.20 CEH18905.1 - 2.9e-52 177.1 0.1 6.5e-52 176.0 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CEH18905.1 - 1.5e-31 109.3 0.0 2.7e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CEH18905.1 - 3.3e-18 65.5 0.1 8.4e-18 64.2 0.0 1.8 2 0 0 2 2 2 1 WGR domain BRCT PF00533.26 CEH18905.1 - 1.9e-09 37.8 0.0 4.2e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CEH18905.1 - 2.8e-08 33.6 0.0 5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CEH18905.1 - 6.8e-06 26.4 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain CDC45 PF02724.14 CEH18905.1 - 1.4 7.1 4.9 2.4 6.4 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 CEH18905.1 - 7.9 5.7 7.0 16 4.7 7.0 1.4 1 0 0 1 1 1 0 NOA36 protein PalH PF08733.10 CEH18906.1 - 0.28 10.1 2.4 0.21 10.6 0.4 1.8 1 1 1 2 2 2 0 PalH/RIM21 Sporozoite_P67 PF05642.11 CEH18907.1 - 0.034 12.3 6.3 0.037 12.1 6.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PH PF00169.29 CEH18908.1 - 3.4e-36 123.9 3.3 5.5e-19 68.6 3.5 3.3 3 0 0 3 3 3 3 PH domain PH_3 PF14593.6 CEH18908.1 - 6.2e-18 64.8 4.7 9.6e-07 28.9 2.8 3.2 3 0 0 3 3 3 3 PH domain PH_11 PF15413.6 CEH18908.1 - 1.2e-12 48.1 17.0 1.8e-05 25.1 9.8 4.3 3 1 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 CEH18908.1 - 1.3e-12 47.8 4.4 1.7e-07 31.4 2.8 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 CEH18908.1 - 6.5e-05 23.3 4.5 0.0039 17.5 1.4 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain PH_4 PF15404.6 CEH18908.1 - 0.00046 20.0 2.8 0.55 10.0 0.1 3.4 2 1 0 3 3 3 2 Pleckstrin homology domain PH_13 PF16652.5 CEH18908.1 - 0.0014 18.5 3.6 0.26 11.1 0.8 3.1 3 0 0 3 3 3 1 Pleckstrin homology domain PH_2 PF08458.10 CEH18908.1 - 0.016 15.6 0.2 2.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Mcp5_PH PF12814.7 CEH18908.1 - 0.043 13.9 8.3 0.68 10.1 0.0 2.9 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology PH_6 PF15406.6 CEH18908.1 - 0.083 13.2 0.0 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Sec3-PIP2_bind PF15277.6 CEH18908.1 - 0.095 12.8 0.8 0.21 11.7 0.8 1.6 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps36_ESCRT-II PF11605.8 CEH18908.1 - 0.6 10.3 3.6 2.8 8.2 0.1 2.8 2 1 1 3 3 3 0 Vacuolar protein sorting protein 36 Vps36 NAP PF00956.18 CEH18909.1 - 3.2e-23 82.3 24.6 7.5e-19 67.9 17.6 3.5 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) OmpH PF03938.14 CEH18909.1 - 0.19 12.1 3.7 0.12 12.7 0.8 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GCIP PF13324.6 CEH18909.1 - 2.7 7.5 12.4 5.9 6.4 12.4 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4611 PF15387.6 CEH18909.1 - 2.9 8.2 11.0 9.2 6.6 11.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 CEH18909.1 - 4 6.7 13.3 8.2 5.6 13.3 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 CEH18909.1 - 8.2 6.9 19.8 18 5.8 19.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 CEH18909.1 - 9.5 6.0 13.9 4.6 7.1 7.9 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Spc7 PF08317.11 CEH18910.1 - 3.7e-44 150.9 6.4 3.7e-44 150.9 6.4 2.5 3 0 0 3 3 3 1 Spc7 kinetochore protein Lzipper-MIP1 PF14389.6 CEH18910.1 - 0.0024 18.1 2.1 0.0024 18.1 2.1 2.9 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 RmuC PF02646.16 CEH18910.1 - 0.012 14.8 0.8 0.012 14.8 0.8 2.5 2 0 0 2 2 2 0 RmuC family Spc7_C2 PF15577.6 CEH18910.1 - 0.039 14.0 0.1 0.084 13.0 0.1 1.5 1 0 0 1 1 1 0 Spc7_C2 Phage_TAC_4 PF08748.11 CEH18910.1 - 0.21 11.9 0.0 0.21 11.9 0.0 3.9 4 1 0 4 4 4 0 Phage tail assembly chaperone IlvN PF07991.12 CEH18911.1 - 7.6e-42 142.7 0.0 1.3e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 CEH18911.1 - 3e-39 134.6 0.0 5e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain DUF240 PF03086.14 CEH18911.1 - 0.045 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF240) Methyltransf_7 PF03492.15 CEH18913.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Cofilin_ADF PF00241.20 CEH18915.1 - 1.1e-09 38.1 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cwf_Cwc_15 PF04889.12 CEH18915.1 - 0.066 12.9 7.4 0.18 11.5 7.4 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PS_Dcarbxylase PF02666.15 CEH18916.1 - 3.7e-70 235.6 0.0 3.8e-68 229.0 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 CEH18916.1 - 0.069 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 MNLL subunit DUF1353 PF07087.11 CEH18917.1 - 0.079 12.7 0.3 17 5.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1353) DMRL_synthase PF00885.19 CEH18918.1 - 2.4e-52 176.5 0.1 2.8e-52 176.3 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase ADAM_spacer1 PF05986.14 CEH18918.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 ADAM-TS Spacer 1 zf-H2C2_2 PF13465.6 CEH18919.1 - 9.5e-09 35.3 0.1 9.5e-09 35.3 0.1 1.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 CEH18919.1 - 3.3e-07 30.4 2.3 1.3e-05 25.4 0.4 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEH18919.1 - 0.0027 18.4 2.6 0.012 16.4 0.4 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEH18919.1 - 0.012 15.6 0.7 0.036 14.1 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 CEH18919.1 - 0.024 15.0 0.9 1.9 9.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF3198 PF11433.8 CEH18919.1 - 0.027 14.4 1.1 7.4 6.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) DUF3437 PF11919.8 CEH18919.1 - 0.036 14.0 0.5 7.1 6.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) ZapB PF06005.12 CEH18919.1 - 0.22 12.0 9.4 1.7 9.2 1.5 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Med8 PF10232.9 CEH18919.1 - 5.1 6.6 7.3 7.2 6.1 0.2 2.7 2 1 1 3 3 3 0 Mediator of RNA polymerase II transcription complex subunit 8 Asparaginase_2 PF01112.18 CEH18921.1 - 1.3e-43 149.2 0.2 3e-21 75.8 0.1 3.0 3 0 0 3 3 3 3 Asparaginase Choline_kin_N PF04428.14 CEH18924.1 - 0.27 11.0 0.6 1.1 9.0 0.2 2.0 2 0 0 2 2 2 0 Choline kinase N terminus RVT_1 PF00078.27 CEH18927.1 - 3.3e-26 92.2 0.1 5.7e-26 91.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CEH18927.1 - 8.3e-22 77.5 0.0 2e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEH18927.1 - 5.5e-19 68.5 0.0 1.5e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 CEH18927.1 - 1.8e-11 43.9 0.0 4.6e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEH18927.1 - 3.1e-10 40.0 1.9 4.1e-10 39.6 0.4 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 CEH18927.1 - 0.014 15.2 0.7 0.1 12.4 0.0 2.9 4 0 0 4 4 4 0 Integrase core domain Adhes-Ig_like PF09085.10 CEH18938.1 - 0.026 14.6 0.1 0.073 13.2 0.0 1.6 1 1 1 2 2 2 0 Adhesion molecule, immunoglobulin-like LacI PF00356.21 CEH18939.1 - 0.28 11.0 0.6 0.59 10.0 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family NGP1NT PF08153.12 CEH18940.1 - 7e-47 158.8 0.9 7.1e-46 155.6 0.0 2.8 3 0 0 3 3 3 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CEH18940.1 - 3.8e-17 62.4 0.0 2.3e-14 53.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH18940.1 - 3.2e-06 26.7 0.5 6.3e-06 25.8 0.1 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 CEH18940.1 - 1.1e-05 25.0 0.1 0.031 13.7 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEH18940.1 - 0.00062 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Roc PF08477.13 CEH18940.1 - 0.029 14.6 0.2 5.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Coatomer_E PF04733.14 CEH18940.1 - 0.03 13.8 0.0 0.074 12.5 0.0 1.6 2 0 0 2 2 2 0 Coatomer epsilon subunit Gtr1_RagA PF04670.12 CEH18940.1 - 0.033 13.5 0.1 0.066 12.6 0.1 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Nop14 PF04147.12 CEH18940.1 - 1.7 6.8 17.1 2.4 6.3 17.1 1.1 1 0 0 1 1 1 0 Nop14-like family Dynamin_N PF00350.23 CEH18940.1 - 2 8.4 7.0 3.4 7.7 0.1 3.6 3 1 1 4 4 4 0 Dynamin family Thg1C PF14413.6 CEH18941.1 - 8.9e-43 145.3 0.0 1.4e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 CEH18941.1 - 2.6e-38 130.9 0.2 1.9e-37 128.1 0.2 2.1 1 1 0 1 1 1 1 tRNAHis guanylyltransferase TRAPPC10 PF12584.8 CEH18942.1 - 8.9e-22 77.5 0.0 2.2e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 EHN PF06441.12 CEH18943.1 - 5.7e-20 71.7 0.0 1.6e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CEH18943.1 - 8.9e-06 25.5 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold SET PF00856.28 CEH18944.1 - 1.1e-16 61.6 0.0 4.4e-16 59.7 0.0 2.0 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 CEH18944.1 - 0.0035 18.0 7.0 0.0035 18.0 7.0 2.2 2 1 0 2 2 2 1 Pre-SET motif RRM_1 PF00076.22 CEH18945.1 - 1.9e-12 46.8 0.0 2.5e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEH18945.1 - 0.013 15.4 0.1 0.039 14.0 0.0 1.8 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 CEH18945.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PAM2 PF07145.15 CEH18946.1 - 0.024 14.3 0.6 0.082 12.6 0.6 2.0 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Arginase PF00491.21 CEH18947.1 - 2.3e-79 266.8 0.0 2.7e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family HMGL-like PF00682.19 CEH18948.1 - 1.5e-79 267.3 1.8 2e-79 266.8 1.8 1.2 1 0 0 1 1 1 1 HMGL-like T3SSipB PF16535.5 CEH18948.1 - 0.0037 17.7 0.6 0.0076 16.7 0.6 1.5 1 0 0 1 1 1 1 Type III cell invasion protein SipB PHP PF02811.19 CEH18949.1 - 0.032 14.5 0.0 0.044 14.1 0.0 1.4 1 1 0 1 1 1 0 PHP domain DnaJ PF00226.31 CEH18950.1 - 2.8e-20 72.2 0.2 5e-20 71.4 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 CEH18950.1 - 8.2e-19 67.8 0.0 1.5e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DEAD PF00270.29 CEH18951.1 - 3.1e-41 141.1 0.0 6.6e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH18951.1 - 4.5e-25 88.2 0.0 1e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CEH18951.1 - 2.7e-18 66.0 0.7 7.3e-18 64.6 0.7 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 CEH18951.1 - 0.0068 16.4 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEH18951.1 - 0.081 13.2 0.0 0.3 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain Dehalogenase PF13486.6 CEH18964.1 - 0.014 14.8 0.2 0.016 14.6 0.2 1.1 1 0 0 1 1 1 0 Reductive dehalogenase subunit THOC2_N PF16134.5 CEH18965.1 - 0.3 9.7 2.8 0.39 9.3 2.8 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus BUD22 PF09073.10 CEH18971.1 - 0.0014 18.1 13.2 0.0019 17.6 13.2 1.1 1 0 0 1 1 1 1 BUD22 Dsh_C PF12316.8 CEH18971.1 - 0.0014 19.0 0.5 0.0014 19.0 0.5 1.8 2 0 0 2 2 2 1 Segment polarity protein dishevelled (Dsh) C terminal Tub_N PF16322.5 CEH18971.1 - 0.12 12.7 10.2 0.18 12.2 10.2 1.3 1 0 0 1 1 1 0 Tubby N-terminal SDA1 PF05285.12 CEH18971.1 - 0.32 10.4 18.6 0.42 10.0 18.6 1.1 1 0 0 1 1 1 0 SDA1 Myc_N PF01056.18 CEH18971.1 - 0.8 9.5 6.8 1.2 8.9 6.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region TFIIF_alpha PF05793.12 CEH18971.1 - 1.1 7.7 18.2 1.5 7.3 18.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 CEH18971.1 - 1.3 7.2 19.6 1.6 6.9 19.6 1.1 1 0 0 1 1 1 0 Nop14-like family UPF0688 PF15772.5 CEH18971.1 - 1.7 8.8 9.6 0.18 12.0 5.0 1.6 2 0 0 2 2 2 0 UPF0688 family Presenilin PF01080.17 CEH18971.1 - 2 7.1 4.4 2.8 6.6 4.4 1.2 1 0 0 1 1 1 0 Presenilin Csm1_N PF18504.1 CEH18973.1 - 0.0022 18.3 1.4 0.63 10.4 0.2 3.3 1 1 3 4 4 4 1 Csm1 N-terminal domain Tup_N PF08581.10 CEH18973.1 - 0.0023 18.2 0.3 0.033 14.5 0.0 2.5 2 0 0 2 2 2 1 Tup N-terminal DUF4686 PF15742.5 CEH18973.1 - 0.0033 16.6 0.8 0.0043 16.2 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) FapA PF03961.13 CEH18973.1 - 0.01 14.5 2.3 0.013 14.1 2.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pkip-1 PF06878.11 CEH18973.1 - 0.014 15.5 1.2 0.69 10.0 1.0 2.2 1 1 0 1 1 1 0 Pkip-1 protein Ax_dynein_light PF10211.9 CEH18973.1 - 0.027 14.4 2.1 0.048 13.6 1.9 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain Rootletin PF15035.6 CEH18973.1 - 0.054 13.5 3.4 0.044 13.8 2.0 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Filament PF00038.21 CEH18973.1 - 0.07 12.7 4.4 1.4 8.5 2.3 2.0 1 1 1 2 2 2 0 Intermediate filament protein ApoO PF09769.9 CEH18973.1 - 0.073 13.0 0.7 1.8 8.5 0.3 2.3 1 1 1 2 2 2 0 Apolipoprotein O PRKG1_interact PF15898.5 CEH18973.1 - 0.083 13.8 0.6 0.083 13.8 0.6 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Occludin_ELL PF07303.13 CEH18973.1 - 0.093 13.5 1.3 2.6 8.8 0.5 2.7 1 1 2 3 3 3 0 Occludin homology domain HALZ PF02183.18 CEH18973.1 - 0.099 12.9 0.2 0.099 12.9 0.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper HalX PF08663.10 CEH18973.1 - 0.16 12.3 2.5 0.56 10.6 0.7 2.6 1 1 1 2 2 2 0 HalX domain OmpH PF03938.14 CEH18973.1 - 0.29 11.5 5.5 0.73 10.2 5.1 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 CEH18973.1 - 4.4 7.4 12.9 0.71 9.9 8.1 2.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein UPF0172 PF03665.13 CEH18975.1 - 0.0092 16.0 0.7 0.0092 16.0 0.7 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) StbA PF06406.11 CEH18975.1 - 0.017 14.4 0.4 0.031 13.5 0.4 1.4 1 0 0 1 1 1 0 StbA protein DinB_2 PF12867.7 CEH18975.1 - 0.065 13.8 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 DinB superfamily FidL_like PF15941.5 CEH18975.1 - 1.2 9.6 3.9 0.47 10.9 0.7 1.9 2 0 0 2 2 2 0 FidL-like putative membrane protein KfrA_N PF11740.8 CEH18975.1 - 3.9 8.2 10.8 5.9 7.6 1.5 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Viral_Beta_CD PF04530.12 CEH18976.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Viral Beta C/D like family tRNA-synt_His PF13393.6 CEH18990.1 - 0.011 15.0 0.9 0.015 14.6 0.9 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase SBD_N PF07005.11 CEH18990.1 - 0.075 12.8 0.6 0.11 12.2 0.6 1.2 1 0 0 1 1 1 0 Sugar-binding N-terminal domain DUF4473 PF14747.6 CEH18995.1 - 0.11 13.1 0.1 0.56 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) G-gamma PF00631.22 CEH18996.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 GGL domain DUF4287 PF14117.6 CEH19002.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) Tim29 PF10171.9 CEH19002.1 - 0.053 13.0 0.3 0.23 10.9 0.1 1.8 1 1 1 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 DUF883 PF05957.13 CEH19002.1 - 0.11 13.1 7.0 0.31 11.7 0.9 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2175 PF09943.9 CEH19002.1 - 0.2 11.9 1.3 0.29 11.5 0.5 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Sporozoite_P67 PF05642.11 CEH19005.1 - 0.16 10.0 0.1 0.19 9.8 0.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Fucose_iso_C PF02952.17 CEH19009.1 - 0.00024 20.8 0.8 0.19 11.4 0.2 2.2 2 0 0 2 2 2 2 L-fucose isomerase, C-terminal domain RCC1 PF00415.18 CEH19009.1 - 0.042 14.5 0.4 18 6.1 0.1 2.7 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat IF2_assoc PF08364.11 CEH19009.1 - 0.57 10.5 1.9 12 6.2 0.2 2.4 2 0 0 2 2 2 0 Bacterial translation initiation factor IF-2 associated region MFS_1 PF07690.16 CEH19010.1 - 8.7e-19 67.6 42.8 8.7e-19 67.6 42.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CEH19010.1 - 7.5e-05 21.7 12.5 7.5e-05 21.7 12.5 2.1 2 0 0 2 2 2 1 MFS_1 like family DUF1256 PF06866.11 CEH19010.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) ATPase_gene1 PF09527.10 CEH19010.1 - 8.4 6.7 19.9 6.2 7.1 6.5 4.0 2 2 1 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter AMP-binding PF00501.28 CEH19011.1 - 3.6e-35 121.4 0.0 6.5e-33 113.9 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 CEH19011.1 - 4.7e-11 42.3 0.0 7.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CEH19011.1 - 2.8e-08 33.5 0.0 4.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family EF-hand_7 PF13499.6 CEH19012.1 - 9e-13 48.5 0.3 1e-06 29.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEH19012.1 - 1.1e-11 43.7 2.3 0.00012 21.7 0.1 3.3 4 1 1 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 CEH19012.1 - 4.8e-11 41.4 1.0 0.00023 20.5 0.0 3.4 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 CEH19012.1 - 3.2e-06 27.3 0.0 0.00035 20.8 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CEH19012.1 - 2.4e-05 24.1 0.2 0.0022 17.8 0.0 3.2 2 2 2 4 4 4 1 EF-hand domain pair EF-hand_11 PF08976.11 CEH19012.1 - 0.021 15.7 0.0 0.036 14.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 CEH19012.1 - 0.026 14.0 0.1 0.65 9.6 0.0 2.6 2 0 0 2 2 2 0 EF hand GPHH PF16905.5 CEH19012.1 - 0.13 12.0 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated zinc_ribbon_15 PF17032.5 CEH19018.1 - 6.1e-07 30.1 0.1 1e-06 29.4 0.1 1.3 1 0 0 1 1 1 1 zinc-ribbon family zf-FPG_IleRS PF06827.14 CEH19018.1 - 0.022 14.6 2.6 0.86 9.5 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn_ribbon_SprT PF17283.2 CEH19018.1 - 0.023 14.6 1.6 0.073 13.0 1.5 1.8 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 CEH19018.1 - 0.32 11.0 5.6 0.73 9.9 5.6 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DNA_ligase_A_M PF01068.21 CEH19019.1 - 1.4e-53 181.6 0.1 7.4e-52 176.0 0.1 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CEH19019.1 - 3e-43 148.1 0.0 5.6e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CEH19019.1 - 3.1e-23 82.2 0.0 7.9e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region eIF-3c_N PF05470.12 CEH19019.1 - 1.6e-05 23.4 0.0 8.5e-05 21.1 0.0 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_ligase_OB_2 PF14743.6 CEH19019.1 - 0.033 14.2 0.1 6.1 6.9 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain Nop14 PF04147.12 CEH19019.1 - 5.9 5.0 29.8 9.1 4.3 29.8 1.2 1 0 0 1 1 1 0 Nop14-like family SHS2_Rpb7-N PF03876.17 CEH19020.1 - 1.2e-11 44.8 0.0 1.9e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CEH19020.1 - 6.1e-11 42.5 0.3 1.3e-10 41.4 0.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DUF4234 PF14018.6 CEH19021.1 - 0.00025 21.1 0.3 0.0062 16.6 1.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4234) Use1 PF09753.9 CEH19021.1 - 0.013 15.3 0.0 0.016 14.9 0.0 1.2 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF2201_N PF13203.6 CEH19024.1 - 0.045 13.3 1.0 0.077 12.6 1.0 1.5 1 1 0 1 1 1 0 Putative metallopeptidase domain Filaggrin PF03516.13 CEH19024.1 - 1.4 9.7 6.1 0.23 12.2 1.9 1.8 2 0 0 2 2 2 0 Filaggrin CCDC50_N PF15295.6 CEH19027.1 - 0.02 15.1 1.8 0.51 10.5 0.1 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus DUF2642 PF10842.8 CEH19027.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) PTS_2-RNA PF01885.16 CEH19028.1 - 1e-63 214.7 0.0 8.8e-38 130.2 0.0 2.1 1 1 1 2 2 2 2 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF3856 PF12968.7 CEH19028.1 - 0.083 13.0 1.0 9.2 6.3 0.1 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) Mgm101p PF06420.12 CEH19029.1 - 3.5e-79 264.2 0.0 4.2e-79 264.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Pex19 PF04614.12 CEH19030.1 - 3.5e-63 213.6 0.5 1.2e-62 211.9 0.0 1.8 1 1 1 2 2 2 1 Pex19 protein family KinB_sensor PF16767.5 CEH19030.1 - 0.033 14.7 0.1 0.072 13.6 0.1 1.5 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB BID PF06393.11 CEH19030.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 BH3 interacting domain (BID) Upf2 PF04050.14 CEH19030.1 - 0.16 12.7 3.8 6.6 7.5 0.0 3.4 3 1 1 4 4 4 0 Up-frameshift suppressor 2 GHMP_kinases_C PF08544.13 CEH19030.1 - 0.35 11.2 6.0 6.8 7.1 0.0 3.8 4 0 0 4 4 4 0 GHMP kinases C terminal Pheromone PF08015.11 CEH19030.1 - 7.4 7.7 9.3 27 5.9 9.3 2.0 1 0 0 1 1 1 0 Fungal mating-type pheromone MFS_1 PF07690.16 CEH19031.1 - 5.9e-18 64.9 49.9 1.5e-09 37.2 25.0 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CEH19031.1 - 1.5e-05 23.6 12.3 3.4e-05 22.5 12.2 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2145 PF09916.9 CEH19032.1 - 0.031 14.0 0.1 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2145) Dicty_REP PF05086.12 CEH19035.1 - 0.018 13.1 5.1 0.021 12.8 5.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NOA36 PF06524.12 CEH19035.1 - 0.25 10.6 8.0 0.33 10.2 8.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4606 PF15379.6 CEH19038.1 - 0.25 11.6 6.0 0.29 11.4 5.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4606) Vps53_N PF04100.12 CEH19040.1 - 5.6e-71 239.5 0.0 1e-70 238.6 0.0 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.13 CEH19040.1 - 2.5e-05 22.8 0.0 6.2e-05 21.6 0.0 1.7 1 1 0 1 1 1 1 Exocyst complex component Sec6 VPS53_C PF16854.5 CEH19040.1 - 2.6e-05 24.2 0.0 6.8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 53 C-terminus Laminin_II PF06009.12 CEH19040.1 - 0.076 13.0 4.0 0.23 11.5 4.0 1.8 1 0 0 1 1 1 0 Laminin Domain II adh_short PF00106.25 CEH19040.1 - 0.083 12.3 3.8 0.16 11.4 3.8 1.4 1 0 0 1 1 1 0 short chain dehydrogenase zf-C2H2 PF00096.26 CEH19041.1 - 2.1e-09 37.3 58.8 0.025 15.0 1.8 9.7 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CEH19041.1 - 0.00011 22.3 0.7 0.4 11.0 0.0 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CEH19041.1 - 0.0007 20.2 58.1 0.048 14.5 1.0 10.3 10 0 0 10 10 10 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEH19041.1 - 0.021 15.2 0.2 0.021 15.2 0.2 8.3 11 0 0 11 11 11 0 Zinc-finger double domain zf-met PF12874.7 CEH19041.1 - 0.045 14.2 1.0 4.1 7.9 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 CEH19041.1 - 0.067 13.5 20.7 0.048 14.0 1.0 6.2 5 1 1 6 6 6 0 C2H2-type zinc ribbon P5CR_dimer PF14748.6 CEH19043.1 - 2.7e-23 82.2 2.9 2.7e-23 82.2 2.9 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CEH19043.1 - 9.2e-15 55.0 0.6 5.4e-11 42.9 0.0 2.8 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent GPHR_N PF12537.8 CEH19043.1 - 0.14 12.3 0.8 0.31 11.1 0.8 1.5 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal Aminotran_3 PF00202.21 CEH19046.1 - 2.1e-123 412.0 0.0 2.5e-123 411.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CEH19046.1 - 0.0002 20.7 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CEH19046.1 - 0.014 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Haem_degrading PF03928.14 CEH19047.1 - 1e-19 70.8 0.0 1.4e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Haem-degrading FAD_binding_4 PF01565.23 CEH19050.1 - 1.6e-15 57.0 1.3 2.9e-15 56.2 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CEH19050.1 - 4.2e-07 30.0 0.3 1e-06 28.7 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like HpcH_HpaI PF03328.14 CEH19051.1 - 4.6e-30 104.4 0.0 5.5e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 CEH19051.1 - 0.028 13.5 0.0 0.098 11.7 0.0 1.7 2 0 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain p450 PF00067.22 CEH19052.1 - 7.1e-62 209.6 0.0 9.3e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MHYT PF03707.16 CEH19052.1 - 0.13 12.5 0.9 0.28 11.4 0.9 1.5 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Trp_DMAT PF11991.8 CEH19053.1 - 6.9e-43 147.4 0.0 9.2e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase MOR2-PAG1_N PF14222.6 CEH19057.1 - 4.4e-123 412.1 0.0 8.4e-123 411.2 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 CEH19057.1 - 5.4e-83 278.7 0.2 5.4e-83 278.7 0.2 2.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 CEH19057.1 - 1.5e-28 99.1 0.1 7.3e-14 50.4 0.0 3.6 3 1 0 3 3 3 3 Cell morphogenesis central region DUF664 PF04978.12 CEH19057.1 - 0.035 14.5 1.3 0.16 12.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF664) LIG3_BRCT PF16759.5 CEH19057.1 - 0.04 14.2 0.1 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain HEAT_EZ PF13513.6 CEH19057.1 - 0.066 13.7 0.0 3.3 8.3 0.0 4.1 3 0 0 3 3 3 0 HEAT-like repeat HHH PF00633.23 CEH19058.1 - 0.00011 21.9 0.2 0.00027 20.7 0.2 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CEH19058.1 - 0.013 16.1 0.0 0.029 15.0 0.0 1.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain Transposase_20 PF02371.16 CEH19058.1 - 0.029 14.7 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family Sad1_UNC PF07738.13 CEH19060.1 - 1.9e-23 82.9 0.0 6.6e-12 45.6 0.0 2.5 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal DUF3560 PF12083.8 CEH19060.1 - 0.045 13.9 0.7 0.045 13.9 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) Mei5 PF10376.9 CEH19060.1 - 6.9 6.5 8.4 0.31 10.9 1.5 2.0 2 0 0 2 2 2 0 Double-strand recombination repair protein 3HCDH_N PF02737.18 CEH19063.1 - 6.2e-40 137.0 0.9 6.5e-39 133.7 0.9 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CEH19063.1 - 2.4e-33 114.6 0.1 1.1e-32 112.5 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF2813 PF11398.8 CEH19063.1 - 0.0062 15.9 0.0 0.008 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) PhyH PF05721.13 CEH19064.1 - 2e-46 158.9 0.0 7.4e-45 153.8 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 CEH19064.1 - 0.038 14.4 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase GHMP_kinases_N PF00288.26 CEH19064.1 - 0.11 12.8 3.4 0.21 11.8 0.3 2.3 2 0 0 2 2 2 0 GHMP kinases N terminal domain Chorion_2 PF03964.15 CEH19064.1 - 6.6 7.6 8.9 2.7 8.9 1.9 2.5 2 0 0 2 2 2 0 Chorion family 2 His_Phos_2 PF00328.22 CEH19065.1 - 2.3e-40 139.1 0.0 3.4e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ist1 PF03398.14 CEH19066.1 - 1.9e-49 167.7 3.0 2.4e-49 167.4 3.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway BDHCT PF08072.11 CEH19066.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 BDHCT (NUC031) domain bZIP_1 PF00170.21 CEH19067.1 - 2.6e-08 33.8 15.7 4.9e-08 33.0 15.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CEH19067.1 - 2.3e-05 24.4 11.9 2.3e-05 24.4 11.9 2.2 1 1 1 2 2 2 1 Basic region leucine zipper DivIC PF04977.15 CEH19067.1 - 0.17 11.7 4.7 0.32 10.8 4.7 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4778 PF16008.5 CEH19067.1 - 0.52 10.3 4.1 0.98 9.4 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Zn_clus PF00172.18 CEH19069.1 - 3.6e-07 30.2 12.6 6.2e-07 29.4 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TTSSLRR PF12468.8 CEH19070.1 - 0.003 17.8 1.2 0.0042 17.3 1.2 1.4 1 1 0 1 1 1 1 Type III secretion system leucine rich repeat protein DUF4781 PF16013.5 CEH19070.1 - 0.034 13.0 0.1 0.046 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) HLH PF00010.26 CEH19073.1 - 5e-13 48.8 0.3 9.9e-13 47.8 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4743 PF15916.5 CEH19076.1 - 2.7e-12 46.7 0.0 4.4e-07 29.9 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4743) NUDIX PF00293.28 CEH19076.1 - 0.0025 17.8 0.5 0.0044 17.0 0.5 1.3 1 0 0 1 1 1 1 NUDIX domain TolB_N PF04052.13 CEH19076.1 - 0.18 12.0 0.0 4.6 7.5 0.0 2.8 2 1 1 3 3 3 0 TolB amino-terminal domain MFS_1 PF07690.16 CEH19077.1 - 1.5e-27 96.4 33.6 1.5e-27 96.4 33.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PFK PF00365.20 CEH19078.1 - 9.7e-184 609.2 0.4 5.4e-87 291.7 0.1 3.2 3 0 0 3 3 3 3 Phosphofructokinase PapJ PF14855.6 CEH19078.1 - 0.0013 18.5 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Pilus-assembly fibrillin subunit, chaperone DUF1510 PF07423.11 CEH19078.1 - 0.55 10.4 2.1 7 6.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1510) Myosin_head PF00063.21 CEH19081.1 - 6.4e-255 847.6 0.0 8.6e-255 847.1 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 CEH19081.1 - 8.3e-28 96.7 1.6 8.3e-28 96.7 1.6 3.9 4 1 0 4 4 4 1 DIL domain IQ PF00612.27 CEH19081.1 - 8e-10 37.6 29.5 0.041 13.7 0.2 7.1 7 0 0 7 7 6 5 IQ calmodulin-binding motif AAA_22 PF13401.6 CEH19081.1 - 0.0083 16.4 0.0 0.033 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Fib_alpha PF08702.10 CEH19081.1 - 0.042 14.0 3.2 0.098 12.8 2.4 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 CEH19081.1 - 0.055 14.1 17.2 0.11 13.1 8.8 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_16 PF13191.6 CEH19081.1 - 0.38 11.1 0.0 0.38 11.1 0.0 3.2 2 1 0 3 3 3 0 AAA ATPase domain Fez1 PF06818.15 CEH19081.1 - 0.4 11.1 21.9 0.24 11.8 14.3 2.5 1 1 1 2 2 2 0 Fez1 FapA PF03961.13 CEH19081.1 - 0.7 8.4 6.1 1.2 7.7 6.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A ABC_tran PF00005.27 CEH19081.1 - 0.71 10.4 2.3 4.1 7.9 0.0 2.8 2 1 0 2 2 1 0 ABC transporter FlaC_arch PF05377.11 CEH19081.1 - 1 9.8 7.1 0.35 11.3 0.5 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) ATPase PF06745.13 CEH19081.1 - 1.3 8.3 4.9 11 5.3 0.0 2.8 2 1 1 3 3 3 0 KaiC DUF16 PF01519.16 CEH19081.1 - 1.9 9.0 8.1 14 6.3 0.6 3.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 CEH19081.1 - 2.2 8.3 7.7 4 7.5 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 CEH19081.1 - 2.6 8.1 27.5 0.53 10.4 15.3 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 CEH19081.1 - 3.1 6.3 18.4 0.63 8.6 8.5 2.0 1 1 1 2 2 2 0 AAA domain TMF_DNA_bd PF12329.8 CEH19081.1 - 3.5 7.7 20.4 2.5 8.2 2.4 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 CEH19081.1 - 3.9 6.3 22.2 0.72 8.7 10.3 2.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 CEH19081.1 - 4.3 7.6 23.9 4.2 7.6 6.2 3.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 CEH19081.1 - 4.6 7.6 12.1 2.6 8.4 0.6 3.4 2 1 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4337 PF14235.6 CEH19081.1 - 4.9 7.3 14.2 0.92 9.6 1.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) CtIP_N PF10482.9 CEH19081.1 - 6 6.9 12.7 9.9 6.2 9.4 2.7 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain GAS PF13851.6 CEH19081.1 - 9.6 5.5 18.0 26 4.1 18.0 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATP-synt_ab PF00006.25 CEH19082.1 - 2e-61 207.4 0.0 3e-61 206.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CEH19082.1 - 2.1e-23 82.6 1.8 6.2e-23 81.1 1.8 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 CEH19082.1 - 0.0019 18.1 0.1 0.0038 17.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CEH19082.1 - 0.0092 16.4 0.4 0.028 14.8 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CEH19082.1 - 0.025 15.0 0.0 0.21 12.0 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 CEH19082.1 - 0.03 14.3 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CEH19082.1 - 0.041 13.8 0.2 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 CEH19082.1 - 0.043 13.2 0.2 0.068 12.5 0.2 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 CEH19082.1 - 0.1 13.1 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 CEH19082.1 - 0.1 12.9 1.0 0.37 11.1 0.4 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEH19082.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 CEH19082.1 - 0.17 11.9 0.1 0.53 10.3 0.1 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T3SS_ATPase_C PF18269.1 CEH19082.1 - 0.19 11.6 0.2 1.2 9.1 0.2 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NB-ARC PF00931.22 CEH19082.1 - 0.2 10.8 2.0 0.18 11.0 0.4 1.6 2 0 0 2 2 2 0 NB-ARC domain TrwB_AAD_bind PF10412.9 CEH19082.1 - 0.24 10.3 0.3 0.4 9.5 0.3 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain HLH PF00010.26 CEH19085.1 - 1.5e-12 47.3 0.3 2.4e-12 46.6 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MAP65_ASE1 PF03999.12 CEH19086.1 - 0.97 8.0 18.9 0.64 8.6 12.2 2.1 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) PIP5K PF01504.18 CEH19087.1 - 1.2e-36 126.3 0.0 2.5e-35 122.0 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PQ-loop PF04193.14 CEH19089.1 - 4.4e-26 90.4 9.7 3.9e-14 52.1 0.4 3.1 4 0 0 4 4 4 2 PQ loop repeat Cwf_Cwc_15 PF04889.12 CEH19090.1 - 0.0036 17.1 13.1 0.0052 16.6 13.1 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CBFD_NFYB_HMF PF00808.23 CEH19090.1 - 0.0043 17.3 0.0 0.0043 17.3 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CEH19090.1 - 0.049 13.8 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PPP4R2 PF09184.11 CEH19090.1 - 0.16 11.5 6.2 0.22 11.1 6.2 1.2 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 CEH19090.1 - 0.17 12.1 13.7 0.27 11.5 13.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 CEH19090.1 - 0.6 10.5 10.7 1.2 9.6 10.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Plasmodium_Vir PF05795.11 CEH19090.1 - 0.7 9.3 1.7 0.84 9.0 1.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nop14 PF04147.12 CEH19090.1 - 1.3 7.1 14.3 1.8 6.7 14.3 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 CEH19090.1 - 4.4 6.0 5.7 5.6 5.6 5.7 1.3 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 CEH19090.1 - 4.9 6.4 12.1 7.7 5.7 12.1 1.2 1 0 0 1 1 1 0 NOA36 protein Fasciclin PF02469.22 CEH19091.1 - 4.4e-21 75.4 0.3 2.4e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain BIR PF00653.21 CEH19092.1 - 1.2e-34 118.8 1.1 2.2e-20 73.1 0.2 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain GFD1 PF17331.2 CEH19092.1 - 0.0012 19.0 2.7 0.0027 17.8 2.7 1.6 1 0 0 1 1 1 1 GFD1 mRNA transport factor Mt_ATP-synt_B PF05405.14 CEH19092.1 - 0.085 12.5 0.3 0.22 11.1 0.3 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) p450 PF00067.22 CEH19093.1 - 1e-51 176.2 0.0 1.4e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.28 CEH19094.1 - 1.4e-28 100.0 0.0 9.8e-20 70.9 0.0 2.9 1 1 2 3 3 3 3 Carboxylesterase family OPT PF03169.15 CEH19095.1 - 2.8e-95 320.2 43.1 3.2e-95 320.0 43.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2207 PF09972.9 CEH19095.1 - 0.0053 15.6 0.5 0.35 9.6 0.0 3.1 3 0 0 3 3 3 1 Predicted membrane protein (DUF2207) ATP-grasp_2 PF08442.10 CEH19100.1 - 3.5e-70 235.7 0.8 6e-70 234.9 0.8 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CEH19100.1 - 4.4e-20 72.0 0.6 1.2e-19 70.7 0.6 1.8 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CEH19100.1 - 9.8e-09 35.0 1.6 1.4e-08 34.5 0.4 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 CEH19100.1 - 0.0002 21.2 2.6 0.0002 21.2 2.6 2.1 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MitMem_reg PF13012.6 CEH19101.1 - 3.6e-23 82.1 1.1 7.4e-23 81.1 1.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CEH19101.1 - 2.9e-13 49.8 0.0 2.3e-11 43.7 0.0 2.5 2 1 0 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ras PF00071.22 CEH19102.1 - 1.9e-62 209.7 0.1 2.2e-62 209.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH19102.1 - 1e-33 116.1 0.0 1.6e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH19102.1 - 1.8e-12 47.1 0.0 2.5e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEH19102.1 - 5.5e-06 26.5 0.0 9.7e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEH19102.1 - 0.00011 21.8 0.2 0.00083 19.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEH19102.1 - 0.00062 19.7 0.2 0.19 11.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CEH19102.1 - 0.0037 17.5 0.1 0.052 13.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CEH19102.1 - 0.0037 17.7 0.1 0.0064 16.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 CEH19102.1 - 0.0048 16.3 0.0 0.0069 15.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEH19102.1 - 0.0076 15.6 0.1 0.017 14.5 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 CEH19102.1 - 0.02 14.6 0.0 0.084 12.6 0.0 1.9 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CEH19102.1 - 0.036 14.6 0.3 0.051 14.1 0.3 1.7 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 CEH19102.1 - 0.037 14.3 0.2 0.31 11.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEH19102.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEH19102.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CEH19102.1 - 0.082 12.3 0.0 0.23 10.8 0.0 1.7 2 1 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 CEH19102.1 - 0.083 12.0 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 CEH19102.1 - 0.084 12.7 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 CEH19102.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MoCF_biosynth PF00994.24 CEH19103.1 - 3.3e-33 114.4 0.0 5.1e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain TAFII55_N PF04658.13 CEH19104.1 - 1.3e-47 161.5 0.0 2.8e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region BING4CT PF08149.11 CEH19105.1 - 2.2e-33 113.9 0.0 4.7e-32 109.6 0.0 2.9 3 0 0 3 3 3 1 BING4CT (NUC141) domain Coatomer_WDAD PF04053.14 CEH19105.1 - 6.8e-07 28.7 0.0 1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CEH19105.1 - 0.00064 20.5 0.2 0.79 10.7 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH19105.1 - 0.083 13.2 0.0 3.6 7.9 0.0 2.8 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ras PF00071.22 CEH19108.1 - 1.4e-51 174.3 0.0 1.8e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEH19108.1 - 2.2e-33 115.0 0.0 3.2e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEH19108.1 - 4.5e-12 45.8 0.0 6.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEH19108.1 - 4.4e-06 26.2 0.0 5.4e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEH19108.1 - 6.4e-05 22.6 0.0 0.0026 17.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 CEH19108.1 - 0.0021 17.6 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 CEH19108.1 - 0.0059 16.1 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CEH19108.1 - 0.0073 16.2 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CEH19108.1 - 0.011 16.0 1.3 0.071 13.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CEH19108.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 CEH19108.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 CEH19108.1 - 0.046 13.3 0.0 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CEH19108.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CEH19108.1 - 0.052 12.9 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 KaiC Pox_A32 PF04665.12 CEH19108.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.18 CEH19108.1 - 0.22 10.8 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 CEH19108.1 - 0.23 11.2 0.0 1 9.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DAHP_synth_2 PF01474.16 CEH19110.1 - 9.8e-162 538.4 0.0 1.1e-161 538.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family NAD_binding_2 PF03446.15 CEH19112.1 - 0.12 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CEH19112.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Cation_ATPase_C PF00689.21 CEH19113.1 - 3e-28 98.8 8.4 3e-28 98.8 8.4 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CEH19113.1 - 5.8e-18 64.8 0.0 1.1e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEH19113.1 - 1.3e-15 58.2 0.3 8.9e-07 29.4 0.1 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEH19113.1 - 5e-12 45.3 0.0 5e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 CEH19113.1 - 1.7e-06 27.7 1.8 1.7e-06 27.7 1.8 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEH19113.1 - 0.00057 19.7 0.5 0.002 17.9 0.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RVT_1 PF00078.27 CEH19114.1 - 7.2e-21 74.7 0.3 1.9e-20 73.3 0.2 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 CEH19114.1 - 0.00026 20.9 4.3 0.00065 19.7 4.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CEH19114.1 - 0.036 14.3 2.8 0.23 11.8 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Phage_Mu_Gam PF07352.12 CEH19114.1 - 0.097 12.6 1.8 0.11 12.4 0.5 1.7 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Asp_protease_2 PF13650.6 CEH19114.1 - 0.16 12.6 0.1 0.62 10.7 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Herpes_UL6 PF01763.16 CEH19114.1 - 0.18 10.3 0.8 0.27 9.7 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like CCD48 PF15799.5 CEH19114.1 - 0.55 8.5 6.3 0.88 7.8 6.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 zf-CCHC_3 PF13917.6 CEH19114.1 - 0.64 10.0 3.9 0.33 10.9 0.3 2.2 2 0 0 2 2 2 0 Zinc knuckle Integrase_H2C2 PF17921.1 CEH19115.1 - 7.9e-21 73.9 0.1 2.3e-20 72.4 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEH19115.1 - 1.1e-12 48.2 0.0 2.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CEH19115.1 - 0.04 14.2 0.2 0.15 12.3 0.2 2.1 1 0 0 1 1 1 0 H2C2 zinc finger rve PF00665.26 CEH19118.1 - 4.1e-18 65.7 0.0 1.2e-17 64.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 CEH19118.1 - 1.6e-15 57.3 0.2 3.4e-15 56.2 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEH19118.1 - 1.1e-12 47.9 0.1 2.4e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CEH19118.1 - 2.9e-05 24.0 0.0 5.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CEH19118.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 CEH19118.1 - 0.047 13.5 0.1 0.87 9.4 0.0 2.8 3 0 0 3 3 3 0 Integrase core domain Retrotrans_gag PF03732.17 CEH19119.1 - 0.00022 21.4 1.2 0.00064 19.9 0.4 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 CEH19119.1 - 0.0016 18.4 3.1 0.0027 17.7 3.1 1.4 1 0 0 1 1 1 1 Zinc knuckle MCM_N PF14551.6 CEH19119.1 - 0.011 16.3 0.0 7.3 7.2 0.0 2.5 2 0 0 2 2 2 0 MCM N-terminal domain Baculo_PEP_C PF04513.12 CEH19119.1 - 0.22 11.6 3.6 12 6.0 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CD24 PF14984.6 CEH19119.1 - 0.53 10.5 2.7 22 5.4 0.2 2.6 2 0 0 2 2 2 0 CD24 protein Spore_YtfJ PF09579.10 CEH19120.1 - 0.045 13.9 0.1 0.063 13.4 0.1 1.2 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) VID27 PF08553.10 CEH19121.1 - 3e-132 441.0 0.0 4.9e-132 440.3 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain adh_short_C2 PF13561.6 CEH19121.1 - 1.1e-47 162.5 7.5 2e-45 155.2 4.4 3.1 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH19121.1 - 5.1e-43 146.8 2.6 1e-42 145.9 2.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase VID27_PH PF17747.1 CEH19121.1 - 3e-29 101.5 0.6 8e-29 100.1 0.1 2.0 2 1 0 2 2 2 1 VID27 PH-like domain VID27_N PF17748.1 CEH19121.1 - 2.5e-14 53.5 0.3 2.5e-14 53.5 0.3 2.8 2 1 0 2 2 2 1 VID27 N-terminal region KR PF08659.10 CEH19121.1 - 8.4e-13 48.6 1.1 2.3e-12 47.2 0.6 2.0 2 0 0 2 2 2 1 KR domain AdoHcyase_NAD PF00670.21 CEH19121.1 - 0.00091 19.3 0.4 0.0025 17.9 0.4 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 CEH19121.1 - 0.017 15.0 1.0 0.046 13.6 1.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CEH19121.1 - 0.066 12.6 0.1 0.22 10.9 0.1 1.8 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CEH19121.1 - 0.079 12.3 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Rrp15p PF07890.12 CEH19122.1 - 1.4e-28 99.9 0.2 1.4e-28 99.9 0.2 3.0 1 1 1 2 2 2 1 Rrp15p DUF4611 PF15387.6 CEH19122.1 - 2.5 8.4 10.4 13 6.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Zn_clus PF00172.18 CEH19123.1 - 0.00025 21.1 4.7 0.00047 20.2 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 CEH19124.1 - 1.9e-67 228.3 0.0 5e-67 226.9 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CEH19124.1 - 1.6e-10 41.2 0.1 3.8e-10 40.0 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEH19124.1 - 0.00016 21.2 0.1 0.00031 20.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_transf_20 PF00982.21 CEH19125.1 - 6.4e-125 417.5 0.0 1.6e-124 416.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEH19125.1 - 9.2e-72 240.9 0.0 1.5e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 CEH19125.1 - 8.2e-05 22.5 0.0 0.17 11.6 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase rve_3 PF13683.6 CEH19125.1 - 0.042 13.6 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain Nefa_Nip30_N PF10187.9 CEH19126.1 - 0.0018 18.6 0.4 0.0018 18.6 0.4 3.9 3 1 1 4 4 4 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF3808 PF10300.9 CEH19126.1 - 0.14 10.9 1.4 0.24 10.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) L31 PF09784.9 CEH19126.1 - 0.25 11.8 4.4 7.1 7.1 0.0 3.5 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 HHH_9 PF17674.1 CEH19126.1 - 1.2 10.1 4.5 0.83 10.6 0.5 3.0 2 1 1 3 3 3 0 HHH domain Tmemb_14 PF03647.13 CEH19127.1 - 2.8e-20 72.8 7.2 3.3e-20 72.6 7.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Ccdc124 PF06244.12 CEH19128.1 - 1.2e-05 25.8 2.0 1.4e-05 25.7 2.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 CEH19128.1 - 7.6e-05 23.1 1.9 9.3e-05 22.8 1.9 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEH19128.1 - 0.0003 21.3 0.3 0.00037 21.0 0.3 1.1 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 CEH19128.1 - 0.00047 20.8 0.6 0.00052 20.6 0.6 1.0 1 0 0 1 1 1 1 YABBY protein MOZ_SAS PF01853.18 CEH19130.1 - 5.6e-76 254.2 0.0 8.6e-76 253.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CEH19130.1 - 6.9e-20 70.4 0.7 2.5e-19 68.6 0.7 2.0 1 0 0 1 1 1 1 MYST family zinc finger domain PHD PF00628.29 CEH19130.1 - 1.9e-18 66.1 20.1 2e-11 43.6 4.4 3.3 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.5 CEH19130.1 - 0.013 15.6 6.5 0.013 15.6 6.5 3.0 1 1 1 2 2 2 0 PHD-finger DPBB_1 PF03330.18 CEH19131.1 - 1.3e-05 25.4 0.1 3e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEH19131.1 - 0.002 17.9 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Barwin family VIR_N PF15912.5 CEH19131.1 - 0.014 15.0 4.6 0.02 14.5 4.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4614 PF15391.6 CEH19131.1 - 0.12 12.4 4.9 0.17 11.8 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) EFTUD2 PF16004.5 CEH19131.1 - 0.13 12.9 8.6 0.19 12.3 8.6 1.2 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Zip PF02535.22 CEH19131.1 - 0.95 8.6 2.8 1.1 8.4 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 CEH19131.1 - 2.2 6.4 8.3 2.8 6.1 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CEH19131.1 - 7.9 5.1 4.8 9.2 4.9 4.8 1.1 1 0 0 1 1 1 0 Presenilin PLDc PF00614.22 CEH19132.1 - 1.5e-15 56.6 0.1 9.3e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CEH19132.1 - 8.1e-13 48.4 0.0 6.6e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 CEH19132.1 - 6.7e-09 35.7 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 PX domain CUE PF02845.16 CEH19133.1 - 2.1e-13 49.7 0.2 7e-13 48.0 0.1 1.9 2 0 0 2 2 2 1 CUE domain UBA PF00627.31 CEH19133.1 - 0.00098 19.0 0.4 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain GET2 PF08690.10 CEH19133.1 - 1.3 8.6 11.0 3.2 7.4 11.0 1.6 1 0 0 1 1 1 0 GET complex subunit GET2 Citrate_synt PF00285.21 CEH19134.1 - 5e-93 312.0 0.0 6e-93 311.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Robl_LC7 PF03259.17 CEH19136.1 - 2e-06 27.5 0.0 1.8e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Roadblock/LC7 domain CAP_N PF01213.19 CEH19136.1 - 2.2 7.7 4.5 3 7.2 4.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4770 PF15994.5 CEH19137.1 - 0.091 13.0 4.5 0.16 12.2 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Spem1 PF15670.5 CEH19137.1 - 0.98 8.9 7.5 1.6 8.3 7.5 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 MFS_1 PF07690.16 CEH19140.1 - 7.5e-29 100.7 43.1 1.3e-28 100.0 36.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Arylesterase PF01731.20 CEH19141.1 - 0.004 17.3 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 2 Arylesterase EMP24_GP25L PF01105.24 CEH19142.1 - 7.2e-41 140.1 0.0 8.5e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PGK PF00162.19 CEH19144.1 - 1.7e-146 488.0 0.8 2e-146 487.8 0.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase TFIIS_C PF01096.18 CEH19145.1 - 1.4e-20 72.9 3.2 1.8e-20 72.5 3.2 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 CEH19145.1 - 0.0015 18.5 0.7 0.0023 17.9 0.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 CEH19145.1 - 0.79 9.9 5.0 4.9 7.4 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain ANAPC4_WD40 PF12894.7 CEH19147.1 - 3.1e-08 33.8 0.2 0.057 13.7 0.0 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEH19147.1 - 5.8e-06 27.0 3.7 0.67 10.9 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Hira PF07569.11 CEH19147.1 - 0.17 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split Coa1 PF08695.10 CEH19148.1 - 4.4e-21 74.8 0.1 9.1e-20 70.6 0.1 2.1 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 HATPase_c PF02518.26 CEH19150.1 - 8e-29 100.4 0.0 1.6e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 CEH19150.1 - 6.9e-26 90.7 3.2 3.8e-09 36.8 0.1 5.8 4 1 0 4 4 4 4 PAS fold Response_reg PF00072.24 CEH19150.1 - 1.3e-25 89.7 0.0 2.8e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 CEH19150.1 - 1.2e-19 70.1 0.1 4.3e-19 68.3 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 CEH19150.1 - 6.8e-15 55.1 0.7 2e-14 53.6 0.7 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CEH19150.1 - 8.8e-15 54.8 0.0 3.5e-09 36.8 0.0 3.9 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 CEH19150.1 - 4e-11 42.9 0.0 0.001 19.1 0.0 5.2 5 0 0 5 5 5 2 PAS fold PAS_8 PF13188.7 CEH19150.1 - 2e-05 24.5 0.0 0.54 10.3 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS_7 PF12860.7 CEH19150.1 - 0.015 15.5 0.4 3.8 7.7 0.0 3.6 3 0 0 3 3 3 0 PAS fold SMC_N PF02463.19 CEH19151.1 - 1.6e-61 207.5 0.0 3.7e-61 206.4 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CEH19151.1 - 6.3e-29 100.7 0.0 2.7e-28 98.6 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CEH19151.1 - 1.1e-14 55.4 7.0 1.1e-14 55.4 7.0 7.1 2 2 3 6 6 3 1 AAA domain AAA_21 PF13304.6 CEH19151.1 - 7.7e-12 45.6 10.8 5.8e-08 32.9 0.0 3.9 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CEH19151.1 - 3.2e-08 33.7 13.3 3.2e-08 33.7 13.3 4.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 CEH19151.1 - 5.4e-08 32.5 0.0 1.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 CEH19151.1 - 0.00048 19.1 13.5 0.00048 19.1 13.5 6.1 4 1 2 6 6 6 4 Spc7 kinetochore protein ADIP PF11559.8 CEH19151.1 - 0.0014 18.7 9.2 0.0014 18.7 9.2 8.5 5 2 4 9 9 9 2 Afadin- and alpha -actinin-Binding SbcCD_C PF13558.6 CEH19151.1 - 0.0087 16.3 0.0 0.053 13.8 0.0 2.4 2 0 0 2 2 1 1 Putative exonuclease SbcCD, C subunit EzrA PF06160.12 CEH19151.1 - 0.028 12.6 0.1 0.028 12.6 0.1 5.6 4 1 1 6 6 6 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 CEH19151.1 - 0.053 13.6 22.0 11 6.0 0.0 5.9 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.27 CEH19151.1 - 0.062 13.8 0.0 0.062 13.8 0.0 6.3 5 2 0 5 5 4 0 ABC transporter Laminin_II PF06009.12 CEH19151.1 - 0.16 12.0 58.2 0.052 13.6 4.9 7.7 4 2 3 7 7 7 0 Laminin Domain II CLZ PF16526.5 CEH19151.1 - 0.2 12.0 0.1 0.2 12.0 0.1 8.5 9 2 2 11 11 9 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_22 PF13401.6 CEH19151.1 - 9.6 6.5 8.6 9.4 6.5 0.0 3.9 4 0 0 4 4 4 0 AAA domain Bromodomain PF00439.25 CEH19152.1 - 1.9e-37 127.2 0.7 7.3e-18 64.4 0.1 2.3 2 0 0 2 2 2 2 Bromodomain DUF3724 PF12521.8 CEH19152.1 - 4 7.6 5.6 33 4.7 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) Xol-1_GHMP-like PF09109.10 CEH19153.1 - 0.038 13.9 0.1 0.063 13.2 0.1 1.2 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like Cnd1 PF12717.7 CEH19157.1 - 4.9e-55 186.0 0.5 3.9e-48 163.6 0.0 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CEH19157.1 - 4.4e-30 104.7 1.7 5.6e-29 101.1 0.0 3.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term Adaptin_N PF01602.20 CEH19157.1 - 2.4e-08 33.0 0.6 6.1e-06 25.1 0.1 2.7 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.6 CEH19157.1 - 1.1e-05 25.7 0.9 0.017 15.5 0.0 4.7 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 CEH19157.1 - 4.5e-05 23.4 6.6 0.26 11.6 0.1 5.5 6 0 0 6 6 6 2 HEAT repeat Cnd3 PF12719.7 CEH19157.1 - 0.0011 18.3 2.0 0.0015 17.8 0.1 2.2 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 CEH19157.1 - 0.0045 17.2 0.4 5.5 7.2 0.0 4.2 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CEH19157.1 - 0.6 10.7 9.5 11 6.7 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat Pkinase PF00069.25 CEH19158.1 - 3.7e-58 197.0 0.0 3.2e-35 121.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEH19158.1 - 2.5e-26 92.5 0.0 9.2e-16 57.9 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.24 CEH19158.1 - 3e-06 27.8 1.0 1.5e-05 25.6 1.0 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 CEH19158.1 - 0.025 14.2 0.3 4.8 6.8 0.0 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CEH19158.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIS PF01380.22 CEH19161.1 - 1.1e-62 209.7 0.3 1.6e-32 112.1 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CEH19161.1 - 5e-16 59.1 0.0 1.2e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CEH19161.1 - 9.1e-12 45.0 0.0 3.7e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CEH19161.1 - 0.00013 21.0 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II YoeB_toxin PF06769.14 CEH19161.1 - 0.042 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 YoeB-like toxin of bacterial type II toxin-antitoxin system GATase_2 PF00310.21 CEH19161.1 - 0.14 10.8 0.0 2.6 6.7 0.0 2.1 1 1 1 2 2 2 0 Glutamine amidotransferases class-II SH3_9 PF14604.6 CEH19162.1 - 4.4e-12 45.7 0.1 6.1e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEH19162.1 - 5.1e-12 45.2 0.1 7.4e-12 44.7 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEH19162.1 - 2e-08 33.8 0.0 3.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain zf-CCHC PF00098.23 CEH19163.1 - 3.8e-19 67.8 21.2 8.5e-09 35.1 3.9 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 CEH19163.1 - 1.4e-06 28.2 7.0 0.061 13.3 0.5 3.3 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 CEH19163.1 - 2e-06 27.5 17.4 0.0012 18.6 0.6 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 CEH19163.1 - 0.2 11.4 8.5 4.5 7.1 0.3 3.1 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_5 PF14787.6 CEH19163.1 - 0.77 9.5 12.2 1.1 9.0 0.5 3.5 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Pmp3 PF01679.17 CEH19164.1 - 2.3e-13 50.1 4.2 3.4e-13 49.6 4.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Mito_carr PF00153.27 CEH19165.1 - 6.2e-36 122.2 7.3 4.5e-17 61.7 0.4 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein SHNi-TPR PF10516.9 CEH19165.1 - 0.024 14.1 1.1 1.8 8.1 0.2 2.3 2 0 0 2 2 2 0 SHNi-TPR DUF3040 PF11239.8 CEH19165.1 - 0.09 13.1 1.2 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Pyridoxal_deC PF00282.19 CEH19166.1 - 3.5e-54 184.0 0.0 6.3e-54 183.1 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 CEH19166.1 - 0.00014 21.2 0.0 0.0003 20.2 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CEH19166.1 - 0.0081 15.1 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Pkinase PF00069.25 CEH19167.1 - 2e-71 240.5 0.0 2.7e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH19167.1 - 4.8e-40 137.5 0.0 7.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CEH19167.1 - 1.9e-16 60.0 0.0 7.8e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CEH19167.1 - 8.2e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEH19167.1 - 0.063 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Aa_trans PF01490.18 CEH19168.1 - 0.00055 18.8 7.1 0.00055 18.8 7.1 1.6 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein DUF2157 PF09925.9 CEH19169.1 - 0.065 13.0 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) YqzE PF14038.6 CEH19169.1 - 0.17 11.9 0.1 0.38 10.8 0.0 1.6 2 0 0 2 2 2 0 YqzE-like protein VRR_NUC PF08774.11 CEH19173.1 - 2e-18 66.4 0.1 4.4e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 VRR-NUC domain BDV_P10 PF06515.11 CEH19173.1 - 0.073 13.1 0.1 9.5 6.3 0.0 2.8 2 0 0 2 2 2 0 Borna disease virus P10 protein Pkinase PF00069.25 CEH19174.1 - 4.7e-56 190.1 0.0 6.1e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH19174.1 - 8.7e-28 97.3 0.0 1.1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEH19174.1 - 0.00025 20.5 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEH19174.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH19174.1 - 0.097 12.6 1.5 1.6 8.6 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Biotin_lipoyl PF00364.22 CEH19175.1 - 2.8e-05 23.9 0.0 4.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Adeno_PV PF03910.13 CEH19175.1 - 0.081 11.6 0.8 0.1 11.3 0.8 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV 2-oxoacid_dh PF00198.23 CEH19176.1 - 7e-55 186.0 0.0 1.1e-54 185.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 CEH19176.1 - 2e-15 56.8 0.1 6.2e-15 55.3 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Got1 PF04178.12 CEH19177.1 - 8.6e-19 68.0 12.7 1.3e-18 67.5 12.7 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF373 PF04123.13 CEH19177.1 - 2.8 7.3 5.6 4.2 6.7 5.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) YrhK PF14145.6 CEH19177.1 - 8.5 6.3 19.4 1.4 8.9 5.3 2.4 1 1 1 2 2 2 0 YrhK-like protein ANAPC5 PF12862.7 CEH19178.1 - 8.6e-12 45.0 2.1 3.1e-11 43.2 2.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 DUF2225 PF09986.9 CEH19178.1 - 0.054 13.2 0.3 0.092 12.5 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 CEH19178.1 - 0.084 12.8 1.1 0.76 9.7 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Aa_trans PF01490.18 CEH19179.1 - 8.9e-24 83.9 28.9 4e-23 81.8 27.6 2.1 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF21 PF01595.20 CEH19179.1 - 3.5 7.3 14.0 6.1 6.5 2.1 3.1 2 1 1 3 3 3 0 Cyclin M transmembrane N-terminal domain RNA_pol_Rbc25 PF08292.12 CEH19180.1 - 2.3e-31 108.7 0.0 3.2e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CEH19180.1 - 3.7e-16 59.2 0.1 9.8e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CEH19180.1 - 0.04 14.3 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain Pam17 PF08566.10 CEH19182.1 - 4.5e-37 127.4 0.0 5e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF4527 PF15030.6 CEH19182.1 - 0.022 14.2 0.5 0.03 13.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) PKS_DE PF18369.1 CEH19182.1 - 0.055 14.0 0.2 0.16 12.6 0.1 1.9 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain Apo-CII PF05355.11 CEH19182.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein C-II DASH_Dad2 PF08654.10 CEH19183.1 - 2.7e-21 75.8 0.0 3.7e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 NUDIX PF00293.28 CEH19185.1 - 1.6e-26 92.9 0.0 2.1e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MMM1 PF10296.9 CEH19186.1 - 2.2e-09 36.9 0.0 1.2e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Sporozoite_P67 PF05642.11 CEH19186.1 - 0.68 7.9 2.4 5 5.1 2.0 2.0 1 1 1 2 2 2 0 Sporozoite P67 surface antigen Glyco_transf_22 PF03901.17 CEH19187.1 - 1.5e-79 268.2 14.8 2.8e-79 267.3 14.8 1.4 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family PRIMA1 PF16101.5 CEH19187.1 - 4.1 7.5 5.2 9.6 6.3 0.5 2.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PMT_2 PF13231.6 CEH19187.1 - 7.9 6.7 15.1 0.081 13.1 2.7 3.1 3 0 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Ku_PK_bind PF08785.11 CEH19188.1 - 9.1e-25 87.1 0.1 3.2e-24 85.4 0.1 2.0 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 CEH19188.1 - 1.3e-24 87.1 0.0 2.8e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 CEH19188.1 - 1.1 10.0 4.8 1.4 9.7 2.3 2.7 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm EamA PF00892.20 CEH19189.1 - 3.1e-14 53.3 7.2 3.1e-14 53.3 7.2 2.3 3 0 0 3 3 3 1 EamA-like transporter family DUF3021 PF11457.8 CEH19189.1 - 0.16 12.3 4.8 0.062 13.6 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Use1 PF09753.9 CEH19190.1 - 2e-14 53.9 0.1 5.6e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 Membrane fusion protein Use1 CDC73_C PF05179.14 CEH19191.1 - 2.3e-42 144.3 0.0 3.2e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal APC_u15 PF16636.5 CEH19193.1 - 0.025 15.0 2.5 0.025 15.0 2.5 3.9 4 0 0 4 4 4 0 Unstructured region on APC between APC_crr regions 5 and 6 LPD25 PF18840.1 CEH19193.1 - 0.038 14.5 1.1 0.13 12.8 1.1 1.9 1 0 0 1 1 1 0 Large polyvalent protein associated domain 25 Sec1 PF00995.23 CEH19194.1 - 3e-124 416.4 0.0 3.6e-124 416.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Snf7 PF03357.21 CEH19196.1 - 4.5e-35 120.8 14.0 5.3e-35 120.6 14.0 1.0 1 0 0 1 1 1 1 Snf7 Bac_GDH PF05088.12 CEH19196.1 - 0.41 8.1 7.6 0.52 7.7 7.6 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase RbsD_FucU PF05025.13 CEH19196.1 - 0.67 10.4 3.5 1 9.8 1.6 2.0 1 1 1 2 2 2 0 RbsD / FucU transport protein family Rad1 PF02144.16 CEH19198.1 - 2.4e-59 200.7 0.0 3.3e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 RNA_pol_Rpb8 PF03870.15 CEH19200.1 - 1e-08 35.5 0.0 1.1e-08 35.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 DUF4410 PF14366.6 CEH19200.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) DHQ_synthase PF01761.20 CEH19201.1 - 6.4e-87 291.0 0.0 8.6e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 CEH19201.1 - 4.5e-05 23.3 2.1 0.0001 22.1 2.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 CEH19201.1 - 0.91 8.3 6.0 4.3 6.0 6.0 2.2 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase FA_hydroxylase PF04116.13 CEH19203.1 - 1.7e-07 31.7 3.1 1.7e-07 31.7 3.1 2.4 2 2 0 2 2 2 1 Fatty acid hydroxylase superfamily ScsC_N PF18312.1 CEH19204.1 - 0.16 11.8 0.1 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Cyt-b5 PF00173.28 CEH19205.1 - 3.4e-10 39.9 0.0 5.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2207 PF09972.9 CEH19205.1 - 0.033 13.0 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RRM_1 PF00076.22 CEH19206.1 - 4.3e-35 119.4 0.0 1.2e-17 63.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CEH19206.1 - 3.6e-17 62.3 0.5 8.2e-09 35.5 0.0 3.4 3 0 0 3 3 3 3 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.8 CEH19206.1 - 0.0021 18.1 0.2 1.1 9.3 0.1 2.7 2 0 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 CEH19206.1 - 0.015 14.9 0.0 0.25 10.9 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAM2 PF07145.15 CEH19206.1 - 0.051 13.3 2.6 0.66 9.8 0.1 2.8 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Nup35_RRM PF05172.13 CEH19206.1 - 0.17 11.9 0.0 0.49 10.4 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Rad51 PF08423.11 CEH19207.1 - 0.0027 17.0 0.0 6 6.1 0.0 3.0 3 0 0 3 3 3 2 Rad51 AAA_19 PF13245.6 CEH19207.1 - 0.0072 16.7 0.3 0.022 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CEH19207.1 - 0.0097 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEH19207.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEH19207.1 - 0.031 14.6 0.0 0.094 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEH19207.1 - 0.035 13.8 0.3 0.18 11.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEH19207.1 - 0.039 14.4 0.0 0.097 13.1 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CEH19207.1 - 0.051 13.2 3.2 1.8 8.1 3.2 2.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CEH19207.1 - 0.07 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.9 CEH19207.1 - 0.14 11.1 0.1 7.1 5.4 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 CEH19207.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 CEH19207.1 - 0.21 11.9 2.1 0.39 11.1 0.8 2.4 2 1 0 2 2 2 0 AAA ATPase domain Methyltransf_23 PF13489.6 CEH19208.1 - 2.3e-19 69.8 0.0 2.9e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH19208.1 - 5.2e-17 62.3 0.0 7.3e-16 58.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH19208.1 - 2.4e-15 57.0 0.1 6.9e-15 55.6 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH19208.1 - 2.1e-13 50.8 0.1 3.1e-11 43.8 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH19208.1 - 4.9e-13 49.1 0.1 1.3e-11 44.5 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEH19208.1 - 1.4e-05 24.6 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase NodS PF05401.11 CEH19208.1 - 0.00073 19.2 0.0 0.042 13.5 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 CEH19208.1 - 0.001 18.5 0.0 1 8.6 0.0 2.1 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 CEH19208.1 - 0.0013 17.8 0.0 0.14 11.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) MTS PF05175.14 CEH19208.1 - 0.0013 18.3 0.0 0.0032 17.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 CEH19208.1 - 0.0022 18.0 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 CEH19208.1 - 0.0057 16.3 0.0 0.0087 15.7 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) DUF2750 PF11042.8 CEH19208.1 - 0.0088 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2750) PrmA PF06325.13 CEH19208.1 - 0.016 14.6 0.0 0.066 12.6 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 CEH19208.1 - 0.025 13.7 0.0 0.47 9.5 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase DUF4936 PF16290.5 CEH19208.1 - 0.076 13.7 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4936) MetW PF07021.12 CEH19208.1 - 0.13 11.9 0.4 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PCMT PF01135.19 CEH19208.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PGM_PMM_I PF02878.16 CEH19214.1 - 2.7e-34 117.9 0.0 4e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CEH19214.1 - 2.7e-28 98.4 0.0 4.5e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CEH19214.1 - 6.3e-15 55.7 0.0 1.5e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 3Beta_HSD PF01073.19 CEH19215.1 - 1.7e-66 224.1 0.0 1.1e-62 211.6 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CEH19215.1 - 9.1e-38 130.1 0.0 1.3e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CEH19215.1 - 5.7e-18 65.4 0.0 2.3e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CEH19215.1 - 2.5e-14 53.0 0.0 3.9e-10 39.3 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 CEH19215.1 - 1.8e-13 50.8 0.0 3.3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CEH19215.1 - 2e-13 50.1 0.0 8e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CEH19215.1 - 1.5e-10 40.7 1.1 2.5e-10 40.0 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CEH19215.1 - 9.1e-06 25.4 0.5 1.5e-05 24.7 0.5 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 CEH19215.1 - 1.6e-05 24.9 0.3 3.9e-05 23.6 0.3 1.6 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 CEH19215.1 - 0.021 15.4 0.0 0.047 14.3 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.21 CEH19215.1 - 0.069 12.9 0.2 4.1 7.1 0.0 2.6 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Macro PF01661.21 CEH19215.1 - 0.086 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Macro domain adh_short PF00106.25 CEH19217.1 - 4.3e-12 45.9 0.6 2.4e-07 30.4 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEH19217.1 - 8.3e-07 28.8 1.6 1.2e-05 25.0 1.6 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH19217.1 - 1.3e-05 25.1 0.2 2.5e-05 24.3 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CEH19217.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Retrotrans_gag PF03732.17 CEH19218.1 - 2.6e-06 27.6 0.0 5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 CEH19220.1 - 9.1e-26 90.7 0.0 3.5e-24 85.6 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 CEH19221.1 - 1.1e-77 255.8 0.6 5.2e-20 71.0 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CEH19221.1 - 4.8e-26 90.7 0.8 4.4e-25 87.6 0.8 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 CEH19221.1 - 0.00023 21.2 0.2 7.5 6.7 0.2 4.9 4 1 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 CEH19221.1 - 0.00037 20.5 3.1 0.097 12.7 1.5 3.4 3 1 1 4 4 4 1 RNA binding motif YflT PF11181.8 CEH19221.1 - 0.0097 16.4 0.9 0.48 11.0 0.3 2.6 2 0 0 2 2 2 1 Heat induced stress protein YflT Nup35_RRM_2 PF14605.6 CEH19221.1 - 0.017 15.1 0.3 11 6.1 0.0 3.8 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Methyltransf_16 PF10294.9 CEH19222.1 - 1.2e-13 51.1 0.0 2e-08 34.2 0.0 3.2 1 1 1 2 2 2 2 Lysine methyltransferase COG6 PF06419.11 CEH19223.1 - 6e-144 480.6 0.0 8.1e-144 480.2 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 IMUP PF15761.5 CEH19223.1 - 6.5 7.5 11.0 9.5 7.0 0.1 3.2 3 0 0 3 3 3 0 Immortalisation up-regulated protein RVT_1 PF00078.27 CEH19225.1 - 1.8e-06 27.6 0.0 3.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CEH19225.1 - 0.00035 20.8 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Med22 PF06179.12 CEH19226.1 - 1.2e-12 47.9 0.2 4e-12 46.3 0.1 2.0 1 1 1 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex RIO1 PF01163.22 CEH19227.1 - 2.7e-67 226.0 0.0 2.7e-67 226.0 0.0 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CEH19227.1 - 0.00038 20.5 0.6 1.3 8.9 0.2 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 CEH19227.1 - 0.014 14.8 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 CEH19227.1 - 0.038 13.3 0.8 0.17 11.2 0.8 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEH19227.1 - 0.067 11.9 0.1 0.067 11.9 0.1 1.8 2 0 0 2 2 2 0 Fungal protein kinase AMP-binding PF00501.28 CEH19228.1 - 1.2e-90 304.2 0.0 1.5e-90 303.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEH19228.1 - 8.4e-11 42.7 0.1 1.6e-10 41.8 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Chorismate_synt PF01264.21 CEH19229.1 - 5.8e-123 409.8 0.0 6.9e-123 409.5 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Prefoldin_2 PF01920.20 CEH19230.1 - 3.2e-13 49.6 3.4 4.3e-13 49.1 3.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4312 PF14189.6 CEH19230.1 - 0.017 15.1 0.3 0.033 14.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) CCDC144C PF14915.6 CEH19230.1 - 0.11 11.6 10.3 0.11 11.6 1.5 2.0 1 1 0 2 2 2 0 CCDC144C protein coiled-coil region Sec20 PF03908.13 CEH19230.1 - 0.51 10.3 4.2 0.54 10.2 1.2 2.1 2 0 0 2 2 2 0 Sec20 Cep57_MT_bd PF06657.13 CEH19230.1 - 0.6 10.6 6.7 0.2 12.1 2.0 2.2 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 CEH19230.1 - 0.77 9.6 6.8 1.4 8.8 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator JIP_LZII PF16471.5 CEH19230.1 - 2.4 8.4 7.0 3.4 7.9 0.2 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 CEH19230.1 - 2.6 8.6 10.2 2.2 8.8 2.6 2.0 1 1 0 2 2 2 0 Apg6 coiled-coil region Ribosomal_L31e PF01198.19 CEH19231.1 - 8e-29 99.7 0.7 1e-28 99.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Ribosomal_S19e PF01090.19 CEH19232.1 - 1.5e-53 180.1 0.0 1.9e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e SGT1 PF07093.11 CEH19232.1 - 0.01 14.3 0.4 0.01 14.3 0.4 1.1 1 0 0 1 1 1 0 SGT1 protein RNA_pol_3_Rpc31 PF11705.8 CEH19232.1 - 0.035 14.4 9.6 0.043 14.1 9.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 CEH19232.1 - 0.13 11.7 8.0 0.15 11.4 8.0 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 CEH19232.1 - 0.15 11.3 11.2 0.18 11.1 11.2 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 CEH19232.1 - 0.42 10.6 5.5 0.54 10.3 5.5 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 CEH19232.1 - 0.59 9.8 11.1 0.71 9.6 11.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 CEH19232.1 - 1.8 6.7 11.4 2 6.5 11.4 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CEH19232.1 - 2.6 6.2 7.3 2.9 6.1 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_1c PF00749.21 CEH19234.1 - 1.3e-105 352.7 0.0 2.2e-105 352.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 CEH19234.1 - 4.6e-32 111.3 0.0 8.3e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 CEH19234.1 - 4.9e-25 88.4 0.0 1.1e-24 87.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 CEH19234.1 - 3.3e-06 27.9 2.4 3.3e-06 27.9 2.4 2.6 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DAO_C PF16901.5 CEH19234.1 - 0.095 12.6 0.3 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase Amidase PF01425.21 CEH19235.1 - 5.5e-92 309.1 1.9 1.9e-88 297.4 1.9 3.0 1 1 0 1 1 1 1 Amidase TEX19 PF15553.6 CEH19235.1 - 0.081 12.9 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Testis-expressed protein 19 Patatin PF01734.22 CEH19235.1 - 0.23 11.6 2.2 0.7 10.0 2.2 1.7 1 1 0 1 1 1 0 Patatin-like phospholipase Aldo_ket_red PF00248.21 CEH19236.1 - 2e-47 161.8 0.0 2.3e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Torus PF16131.5 CEH19237.1 - 1e-34 119.5 0.9 2.1e-34 118.5 0.1 2.0 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 CEH19237.1 - 3.5e-09 36.4 0.0 7.7e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 CEH19237.1 - 0.002 18.0 3.5 0.0038 17.1 3.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 CEH19237.1 - 0.0058 16.6 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 CEH19237.1 - 0.016 15.0 4.9 0.028 14.2 4.9 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEH19237.1 - 0.018 15.1 4.3 0.032 14.3 4.3 1.4 1 0 0 1 1 1 0 Zinc finger domain RRM_5 PF13893.6 CEH19237.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM199X PF15814.5 CEH19237.1 - 4.7 6.2 11.2 19 4.2 9.2 2.2 2 0 0 2 2 2 0 Protein family FAM199X N_BRCA1_IG PF16158.5 CEH19238.1 - 2.4e-18 66.7 0.7 7.2e-12 45.9 0.1 3.6 2 1 0 2 2 2 2 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 CEH19238.1 - 8.9e-07 28.6 11.4 0.00035 20.3 1.6 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type FA_hydroxylase PF04116.13 CEH19239.1 - 1.5e-23 83.6 16.3 1.5e-23 83.6 16.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribonuc_P_40 PF08584.11 CEH19240.1 - 3.8e-23 82.2 0.1 7.2e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Dynamin_N PF00350.23 CEH19241.1 - 3.5e-42 144.3 0.0 7.8e-42 143.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 CEH19241.1 - 2.5e-06 26.9 0.0 1.6e-05 24.3 0.0 2.4 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 CEH19241.1 - 9.1e-05 22.5 0.0 0.00033 20.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Raf1_N PF18578.1 CEH19241.1 - 0.01 16.3 0.7 0.052 14.0 0.7 2.3 1 0 0 1 1 1 1 Rubisco accumulation factor 1 alpha helical domain AAA_21 PF13304.6 CEH19241.1 - 0.049 13.4 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CEH19241.1 - 0.069 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 CEH19241.1 - 0.11 12.8 1.7 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Cir_N PF10197.9 CEH19242.1 - 0.071 13.3 5.1 9.3 6.5 0.0 3.8 3 0 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF3235 PF11574.8 CEH19244.1 - 0.13 13.2 0.6 0.13 13.2 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3235) ABC_membrane PF00664.23 CEH19248.1 - 3.2e-67 227.1 22.8 8.2e-36 124.1 6.4 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 CEH19248.1 - 2.4e-42 144.7 0.1 1.4e-25 90.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEH19248.1 - 3.5e-08 33.1 4.6 0.0012 18.3 0.3 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEH19248.1 - 5.6e-07 29.2 0.8 0.018 14.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEH19248.1 - 4.2e-06 26.8 0.0 0.05 13.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CEH19248.1 - 5.9e-06 26.4 0.0 0.01 15.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 CEH19248.1 - 1.1e-05 25.9 2.1 0.022 15.2 0.8 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 CEH19248.1 - 2e-05 25.2 4.7 0.081 13.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 CEH19248.1 - 4.3e-05 23.8 3.1 0.66 10.2 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 CEH19248.1 - 4.3e-05 23.5 0.1 0.19 11.5 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 CEH19248.1 - 0.00017 21.0 0.3 0.72 9.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.18 CEH19248.1 - 0.0014 18.0 1.1 0.81 9.0 0.1 2.8 2 0 0 2 2 2 2 FtsK/SpoIIIE family CbiM PF01891.16 CEH19248.1 - 0.0018 18.1 1.1 0.0018 18.1 1.1 2.2 2 1 0 2 2 1 1 Cobalt uptake substrate-specific transmembrane region cobW PF02492.19 CEH19248.1 - 0.0039 16.8 1.3 0.98 9.0 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 CEH19248.1 - 0.0039 16.3 0.0 0.9 8.5 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 CEH19248.1 - 0.0043 16.6 0.8 1.3 8.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 CEH19248.1 - 0.0045 16.9 3.9 1.3 8.9 0.1 3.0 3 0 0 3 3 3 2 NACHT domain NB-ARC PF00931.22 CEH19248.1 - 0.0072 15.5 0.5 0.55 9.4 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 CEH19248.1 - 0.014 15.4 7.5 0.15 12.1 0.0 3.1 4 0 0 4 4 2 0 Dynamin family AAA_15 PF13175.6 CEH19248.1 - 0.016 14.9 0.5 1.2 8.8 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 CEH19248.1 - 0.031 14.0 1.0 2.2 7.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CEH19248.1 - 0.032 14.3 0.2 0.032 14.3 0.2 2.3 3 0 0 3 3 2 0 Helicase HerA, central domain Ploopntkinase3 PF18751.1 CEH19248.1 - 0.05 13.5 0.1 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 CEH19248.1 - 0.06 13.5 5.2 9.7 6.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CEH19248.1 - 0.063 13.0 0.4 0.27 11.0 0.0 2.2 3 0 0 3 3 1 0 AAA domain MeaB PF03308.16 CEH19248.1 - 0.068 12.1 0.5 0.78 8.7 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 CEH19248.1 - 0.08 12.8 0.0 2 8.2 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 CEH19248.1 - 0.1 11.8 0.3 4.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 CEH19248.1 - 0.13 12.7 0.0 34 4.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 CEH19248.1 - 0.14 12.0 0.1 9 6.0 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CEH19248.1 - 0.15 12.6 3.6 12 6.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain Septin PF00735.18 CEH19248.1 - 0.16 11.2 0.0 6.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Septin Pox_A32 PF04665.12 CEH19248.1 - 0.17 11.3 0.5 0.71 9.3 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein DEAD PF00270.29 CEH19248.1 - 0.29 10.9 1.1 13 5.5 0.1 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase ABC_ATPase PF09818.9 CEH19248.1 - 0.54 9.0 3.1 1.7 7.4 0.0 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class GSH_synth_ATP PF03917.17 CEH19249.1 - 5.9e-86 288.6 0.0 7.1e-86 288.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CEH19249.1 - 3.2e-24 85.3 1.1 1.1e-13 51.5 0.1 2.7 2 1 1 3 3 3 2 Eukaryotic glutathione synthase DUF202 PF02656.15 CEH19250.1 - 0.11 13.0 12.8 4 7.9 12.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) RHH_5 PF07878.11 CEH19252.1 - 0.017 15.0 1.1 0.043 13.7 0.1 2.3 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HA2 PF04408.23 CEH19254.1 - 2.6e-25 88.8 0.0 5.6e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEH19254.1 - 1.1e-17 64.2 0.0 3.4e-17 62.6 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEH19254.1 - 1.6e-11 44.5 0.0 8.6e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEH19254.1 - 1.4e-08 34.7 0.3 2.9e-08 33.7 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEH19254.1 - 4.1e-06 27.1 0.1 1.2e-05 25.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEH19254.1 - 0.00022 21.6 0.2 0.0005 20.4 0.2 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CEH19254.1 - 0.0031 16.8 0.0 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 CEH19254.1 - 0.022 14.7 1.1 0.054 13.5 0.6 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain SRP54 PF00448.22 CEH19254.1 - 0.041 13.5 0.5 0.18 11.4 0.5 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 CEH19254.1 - 0.054 12.5 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 CEH19254.1 - 0.063 12.6 0.0 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.6 CEH19254.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CEH19254.1 - 0.12 11.8 0.1 0.74 9.2 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein ABC_tran PF00005.27 CEH19254.1 - 0.14 12.7 0.0 0.47 11.0 0.0 1.9 2 0 0 2 2 2 0 ABC transporter 2-Hacid_dh_C PF02826.19 CEH19255.1 - 1.6e-50 171.0 0.0 2.3e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEH19255.1 - 1.8e-33 115.0 0.0 2.4e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CEH19255.1 - 0.00049 20.3 0.1 0.0021 18.2 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 CEH19255.1 - 0.012 15.3 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 ACT domain DUF5615 PF18480.1 CEH19255.1 - 0.018 14.8 0.6 0.34 10.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5615) AdoHcyase_NAD PF00670.21 CEH19255.1 - 0.092 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain tRNA-synt_1g PF09334.11 CEH19256.1 - 3.4e-79 266.4 2.1 3.9e-69 233.3 0.2 3.0 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CEH19256.1 - 1.4e-12 46.7 0.2 2.5e-08 32.7 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CEH19256.1 - 3e-07 30.1 0.1 0.0094 15.3 0.0 3.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 CEH19256.1 - 4.2e-05 23.6 0.1 7.8e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DALR_1 PF05746.15 CEH19256.1 - 0.00045 20.4 0.0 0.00091 19.4 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Toprim_4 PF13662.6 CEH19256.1 - 0.088 13.3 0.4 6 7.4 0.0 2.7 3 0 0 3 3 3 0 Toprim domain SRP19 PF01922.17 CEH19257.1 - 1e-20 74.4 0.0 1.8e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein NDUF_C2 PF06374.11 CEH19258.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.6 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) zn-ribbon_14 PF16503.5 CEH19258.1 - 0.3 10.6 1.2 0.55 9.8 1.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon Condensation PF00668.20 CEH19259.1 - 7.5e-18 64.4 0.0 1.1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Condensation domain ABC_tran PF00005.27 CEH19260.1 - 3.1e-43 147.6 0.1 7.2e-21 75.1 0.2 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CEH19260.1 - 3.6e-35 121.9 12.3 2.5e-26 93.0 5.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CEH19260.1 - 3.7e-11 42.9 6.0 0.00042 19.8 0.2 4.2 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEH19260.1 - 5.6e-09 36.6 0.6 0.00017 22.0 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CEH19260.1 - 6.5e-09 36.0 0.9 0.12 12.2 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEH19260.1 - 4.6e-08 32.7 0.8 0.0018 18.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEH19260.1 - 1.7e-07 31.3 0.0 0.017 15.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CEH19260.1 - 3.6e-07 30.5 0.2 0.0026 18.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 CEH19260.1 - 3.6e-06 26.5 0.1 0.06 12.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family NB-ARC PF00931.22 CEH19260.1 - 7.9e-05 22.0 0.0 0.13 11.4 0.0 2.5 2 1 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.6 CEH19260.1 - 0.00012 21.7 0.0 0.35 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CEH19260.1 - 0.00026 21.0 0.8 0.1 12.7 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 CEH19260.1 - 0.00034 21.2 0.0 0.075 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEH19260.1 - 0.00076 19.7 0.0 0.26 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CEH19260.1 - 0.0013 18.7 1.6 0.45 10.4 0.2 2.6 2 1 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 CEH19260.1 - 0.0017 18.1 0.5 0.063 13.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CEH19260.1 - 0.0079 15.5 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 CEH19260.1 - 0.018 14.8 0.0 3.3 7.4 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CEH19260.1 - 0.025 15.0 0.0 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 CEH19260.1 - 0.027 13.9 2.2 0.54 9.7 0.2 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein ATP-synt_ab PF00006.25 CEH19260.1 - 0.032 13.9 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 CEH19260.1 - 0.033 13.9 0.1 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CEH19260.1 - 0.049 12.9 0.0 0.59 9.3 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_5 PF07728.14 CEH19260.1 - 0.057 13.4 1.1 2.5 8.1 0.0 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) DUF3987 PF13148.6 CEH19260.1 - 0.062 12.3 0.0 6.5 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Dynamin_N PF00350.23 CEH19260.1 - 0.074 13.1 0.1 8 6.5 0.0 2.6 2 0 0 2 2 2 0 Dynamin family T2SSE PF00437.20 CEH19260.1 - 0.082 11.9 0.2 3.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 CEH19260.1 - 0.11 11.9 0.1 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 CEH19260.1 - 0.12 12.0 1.3 5.5 6.5 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 CEH19260.1 - 0.15 12.2 4.6 1.5 8.8 0.6 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 CEH19260.1 - 0.22 11.2 0.0 3.5 7.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain adh_short PF00106.25 CEH19261.1 - 8.9e-29 100.3 0.1 4e-27 95.0 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH19261.1 - 3.2e-17 62.9 0.1 5e-16 59.0 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH19261.1 - 1e-11 45.1 0.2 2.3e-11 43.9 0.2 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CEH19261.1 - 0.017 15.0 0.3 0.034 14.0 0.3 1.8 1 1 0 1 1 1 0 NAD(P)H-binding DFP PF04127.15 CEH19261.1 - 0.018 14.9 0.4 0.061 13.2 0.4 1.8 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.21 CEH19261.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CEH19261.1 - 0.21 11.5 0.1 0.35 10.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Synaptobrevin PF00957.21 CEH19263.1 - 9.8e-14 50.9 1.5 1.1e-13 50.8 0.4 1.6 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 CEH19263.1 - 1.7e-10 40.8 0.0 3.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 CEH19263.1 - 0.067 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region ApoLp-III PF07464.11 CEH19264.1 - 0.017 15.3 2.1 0.033 14.3 1.1 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Phage_Mu_Gam PF07352.12 CEH19264.1 - 0.047 13.6 1.7 0.09 12.7 1.7 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein MHB PF16525.5 CEH19264.1 - 0.047 13.9 0.5 0.099 12.9 0.5 1.6 1 0 0 1 1 1 0 Haemophore, haem-binding DUF4407 PF14362.6 CEH19264.1 - 1.8 7.8 5.7 7.1 5.9 5.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L27 PF01016.19 CEH19265.1 - 1.7e-33 114.5 0.8 2.4e-33 114.0 0.8 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Npa1 PF11707.8 CEH19266.1 - 1.2e-65 222.2 0.0 2e-64 218.1 0.0 2.6 2 1 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.10 CEH19266.1 - 0.044 14.5 0.1 0.52 11.0 0.0 2.7 2 0 0 2 2 2 0 Creb binding Fes1 PF08609.10 CEH19267.1 - 8.7e-25 87.4 0.1 5.1e-24 85.0 0.0 2.4 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 CEH19267.1 - 0.0062 16.7 3.3 5.2 7.6 0.1 4.3 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.23 CEH19267.1 - 0.0094 16.0 0.8 0.34 11.0 0.0 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CEH19267.1 - 0.032 14.6 1.4 1.1 9.7 0.4 3.0 1 1 2 3 3 3 0 HEAT repeats Topoisom_bac PF01131.20 CEH19275.1 - 5.6e-83 279.2 0.0 1.1e-81 275.0 0.0 2.4 2 1 0 2 2 2 1 DNA topoisomerase zf-GRF PF06839.12 CEH19275.1 - 3.3e-28 97.5 16.2 1.1e-15 57.4 5.1 2.8 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC PF00098.23 CEH19275.1 - 1.7e-19 68.9 17.3 4.5e-08 32.8 1.8 3.7 3 0 0 3 3 3 3 Zinc knuckle Toprim PF01751.22 CEH19275.1 - 2.9e-17 62.8 0.0 7.7e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Toprim domain zf-CCHC_2 PF13696.6 CEH19275.1 - 3.4e-12 46.0 16.3 0.00083 19.1 0.8 3.7 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 CEH19275.1 - 2.9e-09 36.7 10.2 0.00077 19.4 0.4 3.6 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 CEH19275.1 - 4.6e-06 26.2 12.6 0.081 12.7 0.2 3.7 3 0 0 3 3 3 3 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 CEH19275.1 - 0.019 15.4 12.3 0.67 10.4 0.6 3.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.6 CEH19275.1 - 1.5 8.6 8.2 2.1 8.1 0.2 3.3 3 0 0 3 3 3 0 Zinc knuckle BCS1_N PF08740.11 CEH19276.1 - 2.6e-48 164.5 0.7 4.1e-48 163.8 0.7 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CEH19276.1 - 6e-16 59.1 0.0 1.3e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CEH19276.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CEH19276.1 - 0.016 15.6 0.5 0.062 13.7 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 CEH19276.1 - 0.027 13.6 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 CEH19276.1 - 0.13 12.7 0.1 0.48 10.8 0.1 2.0 1 1 0 1 1 1 0 RNA helicase ATPase PF06745.13 CEH19276.1 - 0.13 11.5 0.0 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 KaiC DNA_pol_phi PF04931.13 CEH19277.1 - 2.7e-133 445.8 19.4 2.7e-133 445.8 19.4 2.1 2 1 0 2 2 2 1 DNA polymerase phi TLE_N PF03920.15 CEH19278.1 - 0.0013 18.8 0.2 0.0021 18.1 0.1 1.4 1 1 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain HisKA_3 PF07730.13 CEH19278.1 - 0.022 15.2 7.3 0.17 12.5 1.7 2.2 1 1 1 2 2 2 0 Histidine kinase V-SNARE PF05008.15 CEH19278.1 - 0.06 13.7 1.2 0.084 13.3 1.2 1.3 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus PRAI PF00697.22 CEH19278.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase FUSC PF04632.12 CEH19278.1 - 5.7 5.3 8.6 6.6 5.1 8.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family MIP PF00230.20 CEH19287.1 - 1.1e-47 162.7 15.5 1.4e-47 162.3 15.5 1.2 1 0 0 1 1 1 1 Major intrinsic protein Senescence PF06911.12 CEH19289.1 - 0.0053 17.1 15.8 0.11 12.8 9.2 3.2 3 1 1 4 4 4 2 Senescence-associated protein RRF PF01765.19 CEH19289.1 - 0.023 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Glyoxalase_4 PF13669.6 CEH19289.1 - 0.045 14.0 0.1 0.084 13.2 0.1 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ApoLp-III PF07464.11 CEH19289.1 - 0.078 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) HTH_8 PF02954.19 CEH19289.1 - 0.11 12.4 0.7 3.1 7.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Synuclein PF01387.17 CEH19289.1 - 0.3 11.3 20.9 0.27 11.4 18.8 1.7 1 1 0 1 1 1 0 Synuclein V-ATPase_G_2 PF16999.5 CEH19289.1 - 0.4 11.1 3.1 0.36 11.3 0.9 2.0 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Chlorosome_CsmC PF11098.8 CEH19289.1 - 0.47 10.4 13.1 6.7 6.7 12.5 2.4 1 1 1 2 2 2 0 Chlorosome envelope protein C DUF4175 PF13779.6 CEH19291.1 - 0.043 11.7 13.9 0.056 11.3 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) mono-CXXC PF15626.6 CEH19291.1 - 0.16 12.3 0.6 0.41 11.0 0.6 1.7 1 0 0 1 1 1 0 single CXXC unit DUF3043 PF11241.8 CEH19291.1 - 0.69 9.9 5.1 1.1 9.3 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Neur_chan_memb PF02932.16 CEH19291.1 - 1.4 8.9 4.1 1.6 8.7 4.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CEH19291.1 - 2.9 7.6 8.7 3.3 7.4 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CEH19291.1 - 3 6.5 7.3 3.1 6.5 7.3 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CEH19291.1 - 3.4 5.7 4.4 3.6 5.6 4.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCDC53 PF10152.9 CEH19291.1 - 6.5 7.2 11.7 11 6.4 11.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Connexin PF00029.19 CEH19291.1 - 7.1 6.3 5.6 8 6.1 5.3 1.2 1 1 0 1 1 1 0 Connexin Pox_Ag35 PF03286.14 CEH19292.1 - 0.0087 15.9 6.1 0.0087 15.9 6.1 2.7 2 1 0 2 2 2 1 Pox virus Ag35 surface protein Sigma70_ner PF04546.13 CEH19292.1 - 2.9 7.7 8.9 0.86 9.4 5.5 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.11 CEH19292.1 - 9.4 6.2 16.5 0.63 10.1 5.2 2.9 3 0 0 3 3 3 0 RXT2-like, N-terminal Gaa1 PF04114.14 CEH19293.1 - 2.6e-63 214.8 6.9 5.4e-21 75.2 0.1 4.2 1 1 3 4 4 4 4 Gaa1-like, GPI transamidase component Helicase_C_2 PF13307.6 CEH19298.1 - 1.8e-55 187.7 0.0 4.5e-55 186.4 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CEH19298.1 - 1.2e-43 148.8 0.0 2.6e-43 147.7 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 CEH19298.1 - 0.0063 16.3 0.0 0.31 10.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CEH19298.1 - 0.058 13.4 0.1 4.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit YebO PF13974.6 CEH19298.1 - 0.48 10.5 2.2 59 3.8 2.7 2.8 2 0 0 2 2 2 0 YebO-like protein Hydrophobin PF01185.18 CEH19299.1 - 2.7e-15 56.8 8.8 3.5e-15 56.4 8.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin zinc_ribbon_10 PF10058.9 CEH19300.1 - 0.014 15.1 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Hydrophobin PF01185.18 CEH19301.1 - 2.1e-14 53.9 13.4 4.3e-14 52.9 13.4 1.5 1 0 0 1 1 1 1 Fungal hydrophobin Apolipoprotein PF01442.18 CEH19301.1 - 0.11 12.4 0.9 0.15 11.9 0.9 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Vps39_2 PF10367.9 CEH19302.1 - 1.6e-06 28.5 2.6 3.9e-06 27.3 0.0 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 CEH19302.1 - 0.16 12.2 0.5 4.8 7.5 0.0 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 NatB_MDM20 PF09797.9 CEH19303.1 - 2.3e-49 168.4 1.2 3.8e-49 167.7 0.1 1.8 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit FdhE PF04216.12 CEH19303.1 - 3.2 7.6 11.2 14 5.4 0.3 3.7 3 1 1 4 4 4 0 Protein involved in formate dehydrogenase formation Abhydrolase_6 PF12697.7 CEH19306.1 - 1.6e-11 45.3 0.0 2.4e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH19306.1 - 1.5e-08 34.2 0.0 2.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH19306.1 - 0.0035 17.0 0.1 0.015 14.9 0.1 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEH19306.1 - 0.022 14.3 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thiolase_N PF00108.23 CEH19310.1 - 1.2e-93 313.3 3.7 2e-93 312.5 3.7 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEH19310.1 - 8.3e-43 144.9 1.2 1.2e-41 141.2 0.7 2.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEH19310.1 - 5.3e-06 26.2 2.7 5.3e-05 22.9 0.4 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain HpcH_HpaI PF03328.14 CEH19311.1 - 4.5e-33 114.3 0.0 6.4e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 CEH19311.1 - 5.8e-05 22.1 0.1 8.5e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain EF1G PF00647.19 CEH19312.1 - 2.6e-42 143.2 0.1 4.7e-42 142.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CEH19312.1 - 9.9e-22 77.0 0.2 8.4e-10 38.7 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEH19312.1 - 2.4e-14 53.3 0.3 7.8e-06 26.0 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CEH19312.1 - 1.7e-13 50.7 0.0 4.1e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEH19312.1 - 7.6e-10 38.7 2.6 0.0009 19.2 0.1 2.8 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CEH19312.1 - 2.2e-08 34.4 0.0 5.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.19 CEH19312.1 - 1.4e-05 25.6 26.8 0.0066 17.0 11.6 2.8 3 0 0 3 3 2 2 60s Acidic ribosomal protein GST_N_2 PF13409.6 CEH19312.1 - 7.2e-05 23.0 0.0 0.00021 21.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CEH19312.1 - 0.0018 18.0 0.7 2.1 8.2 0.1 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain TamB PF04357.13 CEH19312.1 - 0.16 11.2 1.3 6.7 5.8 0.0 2.2 2 0 0 2 2 2 0 TamB, inner membrane protein subunit of TAM complex RNA_pol_Rpc4 PF05132.14 CEH19312.1 - 0.23 11.9 3.3 4.9 7.6 2.3 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Hc1 PF07432.13 CEH19312.1 - 2.3 8.6 26.6 5.1 7.5 7.8 2.3 2 0 0 2 2 2 0 Histone H1-like protein Hc1 DUF3391 PF11871.8 CEH19312.1 - 4.2 7.9 7.4 25 5.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) IGPD PF00475.18 CEH19314.1 - 7e-60 201.5 0.8 9e-60 201.2 0.5 1.3 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DUF2917 PF11142.8 CEH19314.1 - 0.095 12.1 0.0 0.31 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) zf-Tim10_DDP PF02953.15 CEH19315.1 - 5.6e-19 67.5 0.2 6.7e-19 67.3 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger LSM PF01423.22 CEH19316.1 - 2.6e-20 71.9 0.1 2.9e-20 71.7 0.1 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CEH19316.1 - 0.1 12.3 0.1 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Hfq protein ABC_trans_N PF14510.6 CEH19317.1 - 2e-09 37.9 1.5 6.6e-09 36.3 1.3 2.0 1 1 0 1 1 1 1 ABC-transporter N-terminal ABC_tran PF00005.27 CEH19317.1 - 7.6e-05 23.2 0.1 0.00016 22.2 0.1 1.6 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 CEH19318.1 - 1.7e-56 191.0 47.3 3.5e-33 114.8 19.2 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CEH19318.1 - 2.6e-22 79.8 0.3 8.6e-17 61.9 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 CEH19318.1 - 1e-15 57.4 0.0 1e-15 57.4 0.0 3.8 4 0 0 4 4 3 1 CDR ABC transporter AAA_25 PF13481.6 CEH19318.1 - 7.3e-05 22.4 0.2 0.0002 21.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CEH19318.1 - 0.00024 21.0 0.1 0.49 10.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CEH19318.1 - 0.00032 21.1 0.6 0.00086 19.7 0.6 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CEH19318.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CEH19318.1 - 0.0077 15.9 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 CEH19318.1 - 0.014 14.8 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEH19318.1 - 0.021 15.1 0.3 0.44 10.8 0.1 2.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CEH19318.1 - 0.03 14.1 0.1 0.072 12.8 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.6 CEH19318.1 - 0.032 14.7 0.1 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CEH19318.1 - 0.061 13.2 0.7 0.14 12.1 0.7 1.6 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 CEH19318.1 - 0.077 12.7 2.2 0.16 11.7 0.4 2.2 2 0 0 2 2 2 0 AAA domain DUF150 PF02576.17 CEH19318.1 - 0.19 12.2 0.9 20 5.7 0.2 2.6 1 1 1 2 2 2 0 RimP N-terminal domain Shugoshin_N PF07558.11 CEH19319.1 - 1.7e-05 24.6 0.9 2.7e-05 23.9 0.9 1.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region YesK PF14150.6 CEH19319.1 - 0.24 11.6 0.1 0.4 10.9 0.1 1.3 1 0 0 1 1 1 0 YesK-like protein PKcGMP_CC PF16808.5 CEH19319.1 - 0.42 10.5 2.0 0.84 9.5 2.0 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ost5 PF05251.12 CEH19320.1 - 1.9e-25 88.9 15.8 8.6e-19 67.6 7.1 2.2 2 0 0 2 2 2 2 Oligosaccharyltransferase subunit 5 Fig1 PF12351.8 CEH19320.1 - 0.056 13.4 6.9 1.3 8.9 3.5 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 LapA_dom PF06305.11 CEH19320.1 - 0.52 10.2 0.0 0.52 10.2 0.0 3.0 2 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Neur_chan_memb PF02932.16 CEH19320.1 - 2.1 8.4 5.0 17 5.4 0.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ORC5_C PF14630.6 CEH19320.1 - 7.6 6.0 6.6 11 5.4 1.8 2.1 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus Aldose_epim PF01263.20 CEH19321.1 - 4.3e-11 42.7 0.2 0.00014 21.3 0.0 2.2 2 0 0 2 2 2 2 Aldose 1-epimerase GCV_H PF01597.19 CEH19322.1 - 2.2e-39 134.1 0.1 2.6e-39 133.9 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CEH19322.1 - 0.00023 21.0 0.4 0.00036 20.3 0.4 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 CEH19322.1 - 0.0029 17.5 0.1 0.0048 16.8 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain LysM PF01476.20 CEH19323.1 - 1.4e-07 31.4 0.0 0.019 15.0 0.0 2.3 2 0 0 2 2 2 2 LysM domain Glyco_hydro_9 PF00759.19 CEH19324.1 - 1.5e-07 31.2 0.0 1.8e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF4448 PF14610.6 CEH19324.1 - 0.017 14.9 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Insulin_TMD PF17870.1 CEH19324.1 - 0.12 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Glyco_hydro_9 PF00759.19 CEH19325.1 - 3.4e-31 109.1 0.3 4.8e-31 108.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Bcr-Abl_Oligo PF09036.10 CEH19327.1 - 7.3 6.7 6.4 9.1 6.4 0.1 3.0 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain SO_alpha_A3 PF17806.1 CEH19329.1 - 0.0012 19.1 0.0 2.1 8.8 0.0 2.7 2 1 0 2 2 2 2 Sarcosine oxidase A3 domain Bac_surface_Ag PF01103.23 CEH19330.1 - 1.9e-17 63.7 0.0 3.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Surface antigen DUF3074 PF11274.8 CEH19331.1 - 7.2e-38 130.4 0.0 9.6e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) DUF455 PF04305.14 CEH19332.1 - 2.1e-83 279.6 0.0 3.2e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 CEH19332.1 - 5.9e-05 22.9 0.1 0.00015 21.6 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CEH19332.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain MiaE_2 PF13794.6 CEH19332.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like tRNA-synt_1g PF09334.11 CEH19333.1 - 1.2e-151 504.9 0.0 1.5e-151 504.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CEH19333.1 - 3.9e-08 32.0 0.2 8.3e-06 24.3 0.0 3.4 2 2 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) WHEP-TRS PF00458.20 CEH19333.1 - 0.00028 21.0 3.7 0.00028 21.0 3.7 2.0 2 0 0 2 2 2 1 WHEP-TRS domain Anticodon_1 PF08264.13 CEH19333.1 - 0.0088 16.0 0.5 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DZR PF12773.7 CEH19333.1 - 1.4 9.0 5.3 2.8 8.0 4.4 1.8 1 1 1 2 2 2 0 Double zinc ribbon Diphthami_syn_2 PF01902.17 CEH19334.1 - 4.7e-18 65.5 0.0 4.2e-16 59.1 0.0 2.6 2 1 0 2 2 2 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CEH19334.1 - 9.8e-16 57.9 0.0 2e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP Stb3 PF10330.9 CEH19334.1 - 0.081 13.0 0.1 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Putative Sin3 binding protein Metallophos PF00149.28 CEH19335.1 - 1.2e-37 130.4 0.1 1.7e-37 129.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 CEH19335.1 - 0.0055 16.4 0.0 0.0086 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 CEH19335.1 - 0.15 12.5 0.2 0.52 10.8 0.2 1.9 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain RFC1 PF08519.12 CEH19336.1 - 1.6e-63 213.5 0.0 8.2e-48 162.5 0.0 2.8 3 0 0 3 3 3 2 Replication factor RFC1 C terminal domain BRCT PF00533.26 CEH19336.1 - 4.8e-13 49.3 0.0 9.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 CEH19336.1 - 1.3e-09 38.6 0.0 3.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CEH19336.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 CEH19336.1 - 0.00061 20.3 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain GREB1 PF15782.5 CEH19336.1 - 0.015 12.5 0.0 0.015 12.5 0.0 2.5 2 1 0 2 2 1 0 Gene regulated by oestrogen in breast cancer AAA_16 PF13191.6 CEH19336.1 - 0.016 15.6 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 CEH19336.1 - 0.022 14.5 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 CEH19336.1 - 0.032 14.6 0.0 0.096 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_33 PF13671.6 CEH19336.1 - 0.032 14.4 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CEH19336.1 - 0.054 13.9 0.0 0.23 11.9 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 CEH19336.1 - 0.061 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CEH19336.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glycos_trans_3N PF02885.17 CEH19337.1 - 0.15 11.9 0.3 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain LIM PF00412.22 CEH19338.1 - 7e-11 42.2 23.0 1.6e-05 25.0 1.7 5.7 6 1 0 6 6 6 3 LIM domain DZR PF12773.7 CEH19338.1 - 0.018 15.1 0.8 0.018 15.1 0.8 5.9 6 1 0 6 6 6 0 Double zinc ribbon CDP-OH_P_transf PF01066.21 CEH19339.1 - 4.4e-13 49.8 0.6 4.4e-13 49.8 0.6 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CAP_N PF01213.19 CEH19340.1 - 2.1e-109 365.8 0.2 2.1e-109 365.8 0.2 1.8 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CEH19340.1 - 7.1e-62 207.7 0.5 9.4e-62 207.3 0.5 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CEH19340.1 - 0.037 13.8 3.1 0.064 13.0 3.1 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C Formyl_trans_N PF00551.19 CEH19341.1 - 1.7e-34 119.1 0.1 4.4e-34 117.8 0.0 1.6 2 0 0 2 2 2 1 Formyl transferase ACT PF01842.25 CEH19341.1 - 0.001 18.8 0.1 0.0054 16.5 0.0 2.2 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 CEH19341.1 - 0.012 15.6 0.0 0.08 12.9 0.0 2.3 2 0 0 2 2 2 0 ACT domain Amino_oxidase PF01593.24 CEH19343.1 - 1.9e-46 159.3 0.6 2.8e-45 155.4 0.6 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEH19343.1 - 6.8e-11 42.2 0.4 2.9e-10 40.2 0.4 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CEH19343.1 - 2.8e-08 33.3 1.0 4.7e-08 32.5 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CEH19343.1 - 4.7e-07 29.5 0.2 7e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 CEH19343.1 - 9.3e-06 25.4 5.7 0.00011 22.0 5.7 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEH19343.1 - 3.8e-05 23.1 0.0 5.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEH19343.1 - 0.00021 20.7 1.6 0.002 17.4 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 CEH19343.1 - 0.00022 21.7 0.6 0.017 15.6 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEH19343.1 - 0.00045 19.1 0.8 0.00082 18.2 0.8 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 CEH19343.1 - 0.0013 17.9 0.4 0.0022 17.2 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 CEH19343.1 - 0.0052 16.1 0.3 0.0079 15.5 0.3 1.2 1 0 0 1 1 1 1 Thi4 family DUF1353 PF07087.11 CEH19343.1 - 0.023 14.4 0.0 0.13 12.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1353) RLL PF10036.9 CEH19343.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein PAP_assoc PF03828.19 CEH19344.1 - 6.4e-14 51.9 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CEH19344.1 - 4.2e-06 26.9 0.0 8.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CEH19344.1 - 0.0019 18.3 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Pkinase PF00069.25 CEH19345.1 - 4.4e-46 157.4 0.0 6.1e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH19345.1 - 1.1e-33 116.6 0.0 1.7e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CEH19345.1 - 7.7e-07 29.4 0.0 2.5e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 CEH19345.1 - 2.5e-05 23.2 0.0 5.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEH19345.1 - 0.00055 19.3 0.0 0.0022 17.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like AMP-binding PF00501.28 CEH19346.1 - 8.9e-30 103.6 0.1 9.1e-28 97.0 0.2 2.6 2 1 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 CEH19346.1 - 3.8e-21 75.4 0.0 6.4e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CEH19346.1 - 1.7e-14 53.9 0.0 2.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CEH19346.1 - 2.4e-07 30.5 0.0 3.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 CEH19346.1 - 1.3e-05 25.4 0.5 0.00018 21.8 0.2 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 CEH19346.1 - 0.00024 20.2 0.0 0.00068 18.7 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family SRI PF08236.11 CEH19347.1 - 9.8e-22 76.9 2.8 2.4e-21 75.7 2.8 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 CEH19347.1 - 5.3e-20 72.5 6.7 2.5e-19 70.3 0.1 3.5 3 1 0 3 3 3 2 SET domain AWS PF17907.1 CEH19347.1 - 1.9e-12 47.0 7.0 1.9e-12 47.0 7.0 2.1 2 0 0 2 2 2 1 AWS domain PGP_phosphatase PF09419.10 CEH19348.1 - 8.3e-37 126.4 0.0 1.7e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 CEH19348.1 - 0.037 14.1 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like FlhE PF06366.13 CEH19348.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein FlhE FYVE PF01363.21 CEH19349.1 - 0.043 14.0 0.4 0.14 12.4 0.4 1.8 1 0 0 1 1 1 0 FYVE zinc finger LRR_6 PF13516.6 CEH19349.1 - 0.6 10.3 14.8 14 6.1 0.3 7.1 8 0 0 8 8 8 0 Leucine Rich repeat RRM_1 PF00076.22 CEH19352.1 - 2.4e-13 49.7 0.0 3.4e-10 39.6 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_6 PF00970.24 CEH19353.1 - 2.1e-33 114.6 0.0 3.4e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CEH19353.1 - 6.2e-30 104.1 0.0 9.5e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CEH19353.1 - 1.5e-05 25.2 0.0 0.00045 20.4 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CEH19353.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain ZZ PF00569.17 CEH19354.1 - 0.011 15.6 0.6 0.025 14.4 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Sec63 PF02889.16 CEH19355.1 - 3.1e-69 233.0 0.0 4.9e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 CEH19355.1 - 7.3e-38 130.1 0.7 9.5e-27 93.9 0.2 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 CEH19355.1 - 2.6e-13 50.3 0.0 5.9e-10 39.4 0.0 2.6 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEH19355.1 - 2.2e-08 34.4 1.1 0.0076 16.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain Helicase_C PF00271.31 CEH19355.1 - 3.8e-07 30.4 0.0 0.00022 21.6 0.0 4.2 3 2 0 3 3 3 1 Helicase conserved C-terminal domain AAA_16 PF13191.6 CEH19355.1 - 0.00036 21.0 7.5 0.041 14.3 0.2 3.9 3 0 0 3 3 3 2 AAA ATPase domain Helicase_PWI PF18149.1 CEH19355.1 - 0.001 19.3 0.0 0.0029 17.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain CTU2 PF10288.9 CEH19356.1 - 1.6e-14 54.1 0.4 5.8e-14 52.3 0.0 2.2 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 Kelch_4 PF13418.6 CEH19357.1 - 3.9e-16 58.8 8.5 0.0088 16.0 0.0 5.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CEH19357.1 - 5.6e-11 42.2 0.0 0.0053 16.7 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CEH19357.1 - 6.4e-09 35.9 8.5 8.9e-05 22.7 0.1 5.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CEH19357.1 - 0.00033 20.2 0.1 0.79 9.4 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CEH19357.1 - 0.013 15.5 0.1 4.6 7.4 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Herpes_gE PF02480.16 CEH19357.1 - 0.036 12.8 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E LRS4 PF10422.9 CEH19357.1 - 7.1 6.1 6.5 63 3.0 6.5 2.4 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 GST_C_6 PF17171.4 CEH19359.1 - 3.5e-12 45.9 0.1 8e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CEH19359.1 - 0.00098 19.4 0.2 0.0033 17.7 0.2 1.9 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 CEH19359.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Radial_spoke PF04712.12 CEH19359.1 - 0.27 10.1 3.9 0.43 9.5 3.9 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Cwf_Cwc_15 PF04889.12 CEH19359.1 - 0.95 9.2 10.2 0.024 14.4 3.7 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 CEH19359.1 - 1.4 8.1 7.7 2.3 7.5 7.7 1.3 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 CEH19359.1 - 3.7 7.2 6.8 10 5.7 6.8 1.7 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 CEH19359.1 - 5.3 7.5 19.6 12 6.4 19.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SCA7 PF08313.12 CEH19360.1 - 1.8e-26 91.8 1.0 3.4e-26 90.9 1.0 1.5 1 0 0 1 1 1 1 SCA7, zinc-binding domain zf-C2HC_2 PF13913.6 CEH19360.1 - 0.004 17.0 0.2 0.0076 16.1 0.2 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type DUF4746 PF15928.5 CEH19360.1 - 1.1 8.7 4.2 0.15 11.5 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Pox_MCEL PF03291.16 CEH19361.1 - 1.1e-71 241.7 0.0 1.8e-71 241.0 0.0 1.3 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CEH19361.1 - 2.5e-11 44.1 0.0 5.6e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH19361.1 - 7e-10 38.9 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH19361.1 - 2e-08 34.8 0.0 4.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH19361.1 - 3.2e-07 30.9 0.0 6.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH19361.1 - 7.5e-07 29.1 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEH19361.1 - 0.00098 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 CEH19361.1 - 0.0084 15.3 0.0 0.04 13.1 0.0 2.0 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_PK PF05891.12 CEH19361.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Mor PF08765.11 CEH19362.1 - 0.043 13.8 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Mor transcription activator family Gp_dh_C PF02800.20 CEH19363.1 - 5.2e-69 230.9 0.1 7.1e-69 230.4 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CEH19363.1 - 4.5e-40 136.1 0.1 1e-39 134.9 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADK PF00406.22 CEH19364.1 - 1.9e-57 193.6 0.1 2.4e-57 193.3 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEH19364.1 - 4.3e-22 79.0 0.1 1.2e-21 77.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CEH19364.1 - 6.5e-17 61.2 0.2 1.7e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CEH19364.1 - 0.00015 21.9 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEH19364.1 - 0.00038 21.0 0.0 0.0014 19.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CEH19364.1 - 0.015 15.7 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 CEH19364.1 - 0.055 13.2 0.2 2.8 7.6 0.1 2.6 2 1 1 3 3 3 0 Thymidylate kinase AAA_5 PF07728.14 CEH19364.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FMO-like PF00743.19 CEH19365.1 - 7.7e-32 110.4 0.0 3.3e-22 78.6 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CEH19365.1 - 9.1e-11 41.6 0.0 6.8e-06 25.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEH19365.1 - 2e-09 37.1 0.0 1.8e-08 34.0 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEH19365.1 - 2.7e-07 30.7 0.3 3.1e-06 27.3 0.2 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CEH19365.1 - 5.9e-06 26.4 0.2 1.6e-05 25.0 0.1 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CEH19365.1 - 1.7e-05 24.1 0.0 0.00068 18.9 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 CEH19365.1 - 0.0016 17.8 0.0 0.025 13.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 CEH19365.1 - 0.002 17.3 0.2 0.6 9.1 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CEH19365.1 - 0.0069 16.0 0.0 0.097 12.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CEH19365.1 - 0.019 14.2 0.0 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 CEH19365.1 - 0.047 14.3 0.1 0.29 11.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEH19365.1 - 0.05 12.8 0.1 0.082 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 CEH19365.1 - 0.067 11.9 0.1 0.12 11.1 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 CEH19365.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Sod_Fe_N PF00081.22 CEH19366.1 - 5.8e-33 113.2 1.8 7.9e-33 112.8 1.8 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 CEH19366.1 - 2.2e-16 59.9 0.0 4.4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain TFIID-31kDa PF02291.15 CEH19366.1 - 0.16 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Membr_traf_MHD PF10540.9 CEH19367.1 - 1e-14 55.0 1.0 2.3e-08 34.4 0.9 2.8 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 CEH19367.1 - 1.8e-09 37.8 0.0 4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 CEH19367.1 - 0.0016 17.1 0.8 0.0025 16.5 0.1 1.6 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) Uteroglobin PF01099.17 CEH19367.1 - 0.13 12.6 0.0 0.44 10.9 0.0 1.9 1 0 0 1 1 1 0 Uteroglobin family Ldh_1_N PF00056.23 CEH19368.1 - 3.7e-45 153.5 0.4 5.9e-45 152.8 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CEH19368.1 - 1.2e-39 135.9 0.1 2.1e-39 135.1 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CEH19368.1 - 8.3e-05 21.7 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CEH19368.1 - 0.00071 19.5 0.2 0.0024 17.8 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Nop14 PF04147.12 CEH19369.1 - 0.47 8.6 2.7 0.61 8.2 2.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 CEH19369.1 - 7.5 5.6 10.1 10 5.1 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HhH-GPD PF00730.25 CEH19370.1 - 1.9e-08 34.7 0.2 6.4e-08 33.0 0.0 2.1 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein AT_hook PF02178.19 CEH19370.1 - 3.2 7.9 6.8 1.5 8.9 3.7 2.3 2 0 0 2 2 2 0 AT hook motif MFS_1 PF07690.16 CEH19371.1 - 6.3e-42 143.8 37.6 7.2e-40 137.0 36.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3602 PF12223.8 CEH19372.1 - 8.7 7.0 7.8 0.85 10.3 1.7 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3602) ABC1 PF03109.16 CEH19374.1 - 4.6e-30 104.2 0.0 7.1e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 CEH19374.1 - 0.00074 19.0 0.0 0.0066 15.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Complex1_LYR_2 PF13233.6 CEH19375.1 - 4.2e-16 59.4 2.9 6.5e-16 58.9 2.7 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CEH19375.1 - 2.5e-10 40.3 0.4 7e-10 38.8 0.4 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF3829 PF12889.7 CEH19375.1 - 0.053 13.0 0.3 0.069 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF4028 PF13220.6 CEH19375.1 - 0.14 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) Phage-MuB_C PF09077.11 CEH19375.1 - 0.27 11.2 2.2 11 6.0 0.2 2.7 3 0 0 3 3 3 0 Mu B transposition protein, C terminal zf-primase PF09329.11 CEH19377.1 - 3.9e-09 36.2 0.7 3.9e-09 36.2 0.7 2.1 2 0 0 2 2 2 1 Primase zinc finger UPF0029 PF01205.19 CEH19378.1 - 1.7e-30 105.5 0.1 4.8e-30 104.0 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CEH19378.1 - 1.2e-09 38.5 0.0 3.4e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 RWD domain LZ3wCH PF18517.1 CEH19378.1 - 0.12 12.4 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Leucine zipper with capping helix domain Sporozoite_P67 PF05642.11 CEH19378.1 - 0.18 9.8 4.7 0.26 9.3 4.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LRR_4 PF12799.7 CEH19379.1 - 1.2e-16 60.5 16.1 6.8e-06 26.3 2.7 4.6 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEH19379.1 - 7.1e-15 54.5 12.6 2.3e-09 36.9 4.0 4.4 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 CEH19379.1 - 0.015 15.7 16.8 4.9 8.1 0.5 6.7 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 CEH19379.1 - 0.047 13.8 21.2 0.58 10.3 0.2 5.6 6 0 0 6 6 6 0 Leucine Rich repeat DUF3640 PF12342.8 CEH19379.1 - 1.3 8.8 4.0 0.48 10.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) F-box-like PF12937.7 CEH19380.1 - 0.0011 18.8 0.1 0.0026 17.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like Biotin_lipoyl PF00364.22 CEH19381.1 - 3.8e-22 77.9 1.1 8.4e-22 76.8 1.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CEH19381.1 - 1.7e-07 31.4 0.0 4.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CEH19381.1 - 7.3e-05 22.5 0.1 0.00034 20.4 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like Clathrin PF00637.20 CEH19382.1 - 3.5e-25 88.5 0.1 7.1e-25 87.5 0.1 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_1 PF10366.9 CEH19382.1 - 0.0057 16.9 0.2 4.1 7.7 0.0 3.1 3 1 1 4 4 4 2 Vacuolar sorting protein 39 domain 1 SCNM1_acidic PF15805.5 CEH19382.1 - 0.19 11.5 1.6 0.49 10.1 1.6 1.7 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 WD40 PF00400.32 CEH19382.1 - 0.67 10.9 2.1 0.86 10.6 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-rbx1 PF12678.7 CEH19382.1 - 0.68 10.3 2.2 0.62 10.4 0.3 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain FAT PF02259.23 CEH19383.1 - 2.4e-115 385.5 0.2 5.6e-115 384.2 0.2 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CEH19383.1 - 9e-69 232.0 0.0 2.1e-68 230.8 0.0 1.7 2 0 0 2 2 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CEH19383.1 - 2e-58 196.8 0.1 3e-55 186.5 0.0 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CEH19383.1 - 1.1e-42 144.5 0.3 1.1e-42 144.5 0.3 3.2 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 CEH19383.1 - 2.2e-18 66.4 24.8 0.0002 21.7 0.3 11.6 9 1 2 12 12 12 3 HEAT repeats FATC PF02260.20 CEH19383.1 - 9.5e-15 54.1 0.9 3.4e-14 52.4 0.9 2.1 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CEH19383.1 - 1.4e-11 43.6 17.7 0.051 13.8 0.0 10.7 10 0 0 10 10 10 2 HEAT repeat UME PF08064.13 CEH19383.1 - 8.9e-05 22.4 0.7 0.067 13.1 0.0 4.7 4 0 0 4 4 4 1 UME (NUC010) domain Cnd1 PF12717.7 CEH19383.1 - 0.0022 18.0 1.4 5.8 6.9 0.3 4.9 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CEH19383.1 - 0.0069 16.9 34.0 0.8 10.3 0.4 12.4 13 2 2 15 15 14 1 HEAT-like repeat TPR_2 PF07719.17 CEH19383.1 - 0.024 14.7 3.7 7.3 7.0 0.2 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEH19383.1 - 0.031 14.1 2.2 7.1 6.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEH19383.1 - 0.069 13.4 0.8 1.2 9.4 0.1 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 IFRD PF05004.13 CEH19383.1 - 0.075 12.1 7.4 1.8 7.6 0.1 4.4 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) TPR_19 PF14559.6 CEH19383.1 - 0.11 13.0 0.2 4.2 8.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEH19383.1 - 0.26 11.4 2.1 8.8 6.6 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Proteasom_PSMB PF10508.9 CEH19383.1 - 0.52 8.8 2.0 10 4.5 0.0 3.2 4 1 1 5 5 5 0 Proteasome non-ATPase 26S subunit TPR_16 PF13432.6 CEH19383.1 - 0.96 10.2 7.3 19 6.0 0.1 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 CEH19384.1 - 7.8e-17 61.7 0.0 1.5e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH19384.1 - 5e-15 56.0 0.0 1.2e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH19384.1 - 2.9e-08 34.4 0.0 5.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEH19384.1 - 1.6e-06 28.0 0.0 3.1e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEH19384.1 - 2.4e-06 27.5 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEH19384.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pkinase PF00069.25 CEH19385.1 - 2e-67 227.4 0.0 2.5e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEH19385.1 - 2.4e-32 112.2 0.0 3.1e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEH19385.1 - 1.1e-05 24.5 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEH19385.1 - 0.00047 19.6 0.0 0.0014 18.1 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEH19385.1 - 0.00069 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEH19385.1 - 0.0063 15.9 0.0 0.043 13.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 CEH19385.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CEH19385.1 - 0.025 14.2 0.0 0.053 13.1 0.0 1.5 2 0 0 2 2 2 0 RIO1 family DUF3987 PF13148.6 CEH19386.1 - 0.014 14.4 2.9 0.015 14.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF5308 PF17233.2 CEH19386.1 - 0.061 13.6 4.4 0.084 13.1 4.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) RNA_pol_Rpc4 PF05132.14 CEH19386.1 - 4 7.9 7.8 4.8 7.6 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Methyltransf_31 PF13847.6 CEH19389.1 - 9.8e-14 51.4 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEH19389.1 - 1.6e-08 35.2 0.3 2.9e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEH19389.1 - 3.7e-05 24.3 0.0 5.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEH19389.1 - 0.034 14.8 0.0 0.054 14.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CEH19389.1 - 0.037 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 CEH19389.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 CEH19389.1 - 0.055 13.5 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 CEH19389.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase 4HBT PF03061.22 CEH19390.1 - 8.6e-07 29.2 0.0 1.3e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 CEH19390.1 - 0.085 13.0 0.2 0.13 12.4 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) 4F5 PF04419.14 CEH19391.1 - 6e-09 36.6 12.4 6e-09 36.6 12.4 2.8 2 2 0 2 2 2 1 4F5 protein family GST_C_6 PF17171.4 CEH19392.1 - 0.00032 20.4 0.1 0.0014 18.3 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CEH19392.1 - 0.031 15.0 0.0 0.065 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Ion_trans PF00520.31 CEH19393.1 - 0.00015 21.1 14.8 0.00032 20.0 14.8 1.5 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CEH19393.1 - 0.0061 15.3 0.2 0.0061 15.3 0.2 2.2 2 0 0 2 2 2 1 Polycystin cation channel MCPsignal PF00015.21 CEH19393.1 - 0.061 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PLA2_B PF01735.18 CEH19394.1 - 2.2e-18 66.0 0.0 6.9e-09 34.6 0.8 2.2 2 0 0 2 2 2 2 Lysophospholipase catalytic domain Ribosomal_L30 PF00327.20 CEH19395.1 - 6.5e-10 38.8 0.1 1e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e L31 PF09784.9 CEH19396.1 - 2.7e-44 149.8 0.0 3e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 UQ_con PF00179.26 CEH19397.1 - 3.9e-44 149.7 0.0 4.4e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEH19397.1 - 0.0046 16.7 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Per1 PF04080.13 CEH19399.1 - 9.7e-97 323.7 0.1 1.2e-96 323.5 0.1 1.1 1 0 0 1 1 1 1 Per1-like family ALIX_LYPXL_bnd PF13949.6 CEH19399.1 - 0.12 11.7 0.1 0.17 11.1 0.1 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV zf-C2H2 PF00096.26 CEH19400.1 - 4.9e-06 26.7 16.9 0.00079 19.8 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEH19400.1 - 3.4e-05 24.1 4.9 3.4e-05 24.1 4.9 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEH19400.1 - 0.0091 16.8 13.4 0.081 13.8 0.8 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEH19400.1 - 0.21 11.9 2.9 24 5.4 2.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CEH19400.1 - 5.3 7.2 12.7 0.34 11.0 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger 2OG-FeII_Oxy_2 PF13532.6 CEH19401.1 - 3.1e-26 92.8 0.0 7.7e-26 91.5 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ubiquitin_2 PF14560.6 CEH19401.1 - 0.0024 18.3 0.0 0.0053 17.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain UIM PF02809.20 CEH19401.1 - 0.004 17.0 17.2 0.045 13.7 2.6 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif Glyoxal_oxid_N PF07250.11 CEH19401.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Ribosomal_S6 PF01250.17 CEH19402.1 - 3.7e-21 75.2 0.0 4.5e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 TraD PF06412.11 CEH19402.1 - 0.094 12.5 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Conjugal transfer protein TraD Vac_ImportDeg PF09783.9 CEH19403.1 - 6.1e-55 185.4 0.0 3.5e-49 166.7 0.0 2.1 2 0 0 2 2 2 2 Vacuolar import and degradation protein NPR2 PF06218.11 CEH19404.1 - 2.2e-82 277.2 2.9 2.4e-39 135.3 0.8 5.1 3 2 1 4 4 4 4 Nitrogen permease regulator 2 GTP_EFTU PF00009.27 CEH19405.1 - 9.3e-27 93.8 3.8 2.6e-20 72.8 2.8 3.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CEH19405.1 - 7.3e-26 90.3 0.5 1.6e-25 89.3 0.5 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CEH19405.1 - 1.7e-06 28.1 0.1 5.1e-06 26.5 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH19405.1 - 0.024 14.2 0.0 5.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B DotD PF16816.5 CEH19405.1 - 0.024 14.6 0.1 0.65 10.0 0.0 2.8 2 0 0 2 2 2 0 DotD protein GTP_EFTU_D2 PF03144.25 CEH19405.1 - 0.049 14.0 2.6 3.7 8.0 0.2 3.3 3 0 0 3 3 3 0 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CEH19405.1 - 0.075 12.9 0.2 0.53 10.2 0.2 2.4 1 1 0 1 1 1 0 Elongation factor Tu domain 4 DUF3506 PF12014.8 CEH19407.1 - 7.2e-10 39.0 0.0 2.3e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 CEH19407.1 - 0.0019 18.0 0.1 0.0047 16.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEH19407.1 - 0.0063 16.4 0.6 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain Na_Ca_ex PF01699.24 CEH19408.1 - 5.6e-19 68.6 31.6 1.1e-11 44.9 12.9 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 CEH19408.1 - 1.8e-13 51.0 8.7 1.8e-13 51.0 8.7 3.6 3 0 0 3 3 3 1 Inner membrane component domain Otopetrin PF03189.13 CEH19408.1 - 0.12 11.1 0.6 0.4 9.4 0.6 1.8 1 0 0 1 1 1 0 Otopetrin Ufd2P_core PF10408.9 CEH19409.1 - 7.7e-185 616.1 0.0 9.4e-185 615.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CEH19409.1 - 3.8e-26 91.1 2.0 2.6e-25 88.4 0.4 2.9 3 0 0 3 3 3 1 U-box domain CRAL_TRIO_2 PF13716.6 CEH19410.1 - 1.7e-27 96.3 0.1 3.2e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 CEH19410.1 - 2.8e-24 85.7 0.0 4.4e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 CEH19410.1 - 5.6e-06 26.2 0.1 3.7e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain Rtf2 PF04641.12 CEH19411.1 - 2e-50 171.6 4.3 2.9e-50 171.1 4.2 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger Asp PF00026.23 CEH19412.1 - 2e-34 119.5 0.1 2.8e-34 119.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEH19412.1 - 1.2e-07 32.2 4.8 3e-06 27.6 0.3 3.8 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Gram_pos_anchor PF00746.21 CEH19412.1 - 0.096 12.6 7.8 0.046 13.7 2.8 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF3188 PF11384.8 CEH19412.1 - 0.13 12.0 2.9 0.25 11.1 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) SKG6 PF08693.10 CEH19412.1 - 0.37 10.2 7.8 0.62 9.5 7.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M28 PF04389.17 CEH19414.1 - 2.7e-36 125.1 0.0 4e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 DUF2070 PF09843.9 CEH19414.1 - 0.074 11.3 18.9 0.15 10.4 18.9 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short_C2 PF13561.6 CEH19415.1 - 2.5e-49 167.9 5.6 3e-49 167.7 5.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEH19415.1 - 5.4e-43 146.7 2.6 7.1e-43 146.4 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEH19415.1 - 1.3e-08 35.0 3.2 2.9e-08 33.8 3.2 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CEH19415.1 - 0.024 13.8 0.2 0.038 13.1 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Hydrolase_like PF13242.6 CEH19416.1 - 1.2e-05 25.3 0.1 0.0046 17.0 0.0 2.8 3 0 0 3 3 3 2 HAD-hyrolase-like Hydrolase_6 PF13344.6 CEH19416.1 - 8e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PH_10 PF15411.6 CEH19417.1 - 5.9e-25 87.9 0.0 1.2e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_UBOX PF13445.6 CEH19417.1 - 0.00041 20.3 0.1 0.00092 19.2 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger VWA PF00092.28 CEH19417.1 - 0.0048 17.2 0.0 0.057 13.7 0.0 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CEH19417.1 - 0.0049 16.8 0.0 0.018 15.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 CEH19417.1 - 0.0057 17.0 1.7 0.0066 16.8 0.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CEH19417.1 - 0.0066 16.4 0.2 0.014 15.3 0.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEH19417.1 - 0.33 10.8 0.8 0.73 9.7 0.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ndc1_Nup PF09531.10 CEH19419.1 - 3.9 6.1 5.0 4.1 6.0 5.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup 4HBT PF03061.22 CEH19420.1 - 8.8e-11 42.0 0.3 1.5e-10 41.3 0.3 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 CEH19420.1 - 0.00028 21.0 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) HLH PF00010.26 CEH19421.1 - 7.9e-16 57.8 0.3 2.4e-15 56.2 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 CEH19421.1 - 0.0022 18.1 1.1 0.0022 18.1 1.1 2.9 2 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit YL1 PF05764.13 CEH19421.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.8 3 0 0 3 3 3 0 YL1 nuclear protein Sensor PF13796.6 CEH19421.1 - 0.17 11.9 5.1 0.31 11.1 0.0 2.9 2 1 0 2 2 2 0 Putative sensor PHY PF00360.20 CEH19422.1 - 1.1e-26 93.3 0.0 2.6e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region Response_reg PF00072.24 CEH19422.1 - 1.4e-17 63.9 0.0 7.8e-17 61.5 0.0 2.2 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 CEH19422.1 - 1.4e-17 64.2 3.5 1.9e-16 60.6 1.8 2.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 CEH19422.1 - 4.1e-12 46.9 0.2 2.1e-11 44.6 0.0 2.4 2 0 0 2 2 2 1 GAF domain PAS_2 PF08446.11 CEH19422.1 - 1.4e-10 41.8 0.0 3.8e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 CEH19422.1 - 2.9e-10 40.0 1.6 8.5e-10 38.5 1.6 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Endosulfine PF04667.17 CEH19423.1 - 4.9e-27 93.9 0.0 7.6e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Acyl-CoA_dh_1 PF00441.24 CEH19425.1 - 4.5e-29 101.6 0.4 8.2e-29 100.8 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEH19425.1 - 7.4e-18 64.5 0.2 1.7e-17 63.4 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 CEH19425.1 - 5.8e-16 58.4 0.0 1.4e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 CEH19425.1 - 1.6e-12 48.0 0.1 2.8e-11 44.1 0.0 2.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CEH19425.1 - 6.3e-07 29.7 0.2 1.1e-06 29.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain COesterase PF00135.28 CEH19426.1 - 4.4e-60 204.0 0.0 4.2e-59 200.8 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CEH19426.1 - 0.00011 22.1 0.1 0.03 14.2 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEH19426.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1180 PF06679.12 CEH19426.1 - 0.37 11.2 7.2 0.12 12.8 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) SecE PF00584.20 CEH19427.1 - 1.2e-14 53.9 0.0 1.7e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Nucleos_tra2_C PF07662.13 CEH19428.1 - 3.2e-64 216.6 2.0 7.1e-64 215.5 2.0 1.6 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CEH19428.1 - 4.3e-13 49.7 5.8 4.3e-13 49.7 5.8 3.5 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Rpr2 PF04032.16 CEH19429.1 - 3.8e-12 46.3 0.1 7.5e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF3602 PF12223.8 CEH19431.1 - 0.0074 16.9 1.7 0.0074 16.9 1.7 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF3602) Zn_clus PF00172.18 CEH19432.1 - 1.9e-10 40.7 6.1 3.1e-10 40.0 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP1_N PF06424.12 CEH19433.1 - 0.1 13.0 6.4 0.26 11.7 6.4 1.6 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal MMTV_SAg PF01054.17 CEH19433.1 - 3.9 7.0 6.7 3 7.4 2.1 2.1 1 1 1 2 2 2 0 Mouse mammary tumour virus superantigen Inhibitor_I9 PF05922.16 CEH19434.1 - 0.011 16.4 0.0 0.032 14.9 0.0 1.9 1 1 0 1 1 1 0 Peptidase inhibitor I9 zf-CDGSH PF09360.10 CEH19435.1 - 0.01 16.0 0.0 0.04 14.1 0.0 1.9 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type FAM199X PF15814.5 CEH19436.1 - 0.086 11.9 1.9 0.1 11.6 1.9 1.1 1 0 0 1 1 1 0 Protein family FAM199X L51_S25_CI-B8 PF05047.16 CEH19437.1 - 3.8e-05 23.5 0.1 5.5e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain pPIWI_RE_X PF13111.6 CEH19437.1 - 0.012 14.8 0.1 0.015 14.6 0.1 1.1 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain Tcp11 PF05794.13 CEH19438.1 - 5.4e-91 305.9 0.0 1.7e-90 304.3 0.0 1.8 1 1 0 1 1 1 1 T-complex protein 11 LIM PF00412.22 CEH19439.1 - 2.7e-15 56.3 31.8 8.6e-08 32.3 7.0 4.2 4 0 0 4 4 4 3 LIM domain SR-25 PF10500.9 CEH19440.1 - 0.12 12.0 27.7 0.13 11.8 27.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cactin_mid PF10312.9 CEH19441.1 - 1.3e-64 217.6 7.1 2.2e-64 216.8 7.1 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 CEH19441.1 - 1.2e-56 190.0 6.1 1.9e-56 189.4 6.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 CEH19441.1 - 0.014 15.8 0.0 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) peroxidase PF00141.23 CEH19442.1 - 2.3e-47 161.6 0.0 3.6e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase PH_10 PF15411.6 CEH19444.1 - 2.7e-40 137.4 0.0 5.5e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 CEH19444.1 - 1.4e-38 133.0 0.1 2.2e-38 132.3 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 CEH19444.1 - 8.9e-28 96.4 0.0 1.6e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 CEH19444.1 - 9.7e-09 35.0 0.2 2e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 CEH19444.1 - 0.0016 19.0 0.0 0.0044 17.5 0.0 1.8 1 0 0 1 1 1 1 PH domain CH PF00307.31 CEH19444.1 - 0.0056 16.9 0.0 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain PH_17 PF18012.1 CEH19444.1 - 0.18 11.6 0.2 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 PH domain SNase PF00565.17 CEH19445.1 - 4.7e-22 78.5 2.6 1.6e-18 67.1 0.0 2.2 1 1 1 2 2 2 2 Staphylococcal nuclease homologue MIF4G_like_2 PF09090.11 CEH19446.1 - 0.048 13.1 0.4 0.06 12.8 0.4 1.1 1 0 0 1 1 1 0 MIF4G like ThiS PF02597.20 CEH19446.1 - 0.051 14.2 0.2 0.088 13.5 0.2 1.4 1 0 0 1 1 1 0 ThiS family UPF0242 PF06785.11 CEH19446.1 - 0.051 13.7 0.2 0.061 13.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 CEH19446.1 - 0.069 12.0 1.5 0.086 11.7 1.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein E1-E2_ATPase PF00122.20 CEH19447.1 - 2.5e-42 144.4 3.1 2.5e-42 144.4 3.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CEH19447.1 - 1.7e-35 123.2 0.9 4.1e-35 122.0 0.7 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CEH19447.1 - 5e-27 94.1 0.1 3.1e-13 50.0 0.0 2.5 2 0 0 2 2 2 2 Heavy-metal-associated domain Fer2_BFD PF04324.15 CEH19447.1 - 0.0045 17.3 1.1 0.27 11.6 0.2 3.1 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Hydrolase_3 PF08282.12 CEH19447.1 - 0.0068 16.2 0.4 0.014 15.2 0.1 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HTH_AsnC-type PF13404.6 CEH19447.1 - 0.13 12.1 3.4 0.5 10.2 0.1 3.5 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain HAD PF12710.7 CEH19447.1 - 0.15 12.4 0.1 0.71 10.2 0.1 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.21 CEH19448.1 - 2.1e-48 164.5 0.1 6.2e-48 163.1 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CEH19448.1 - 1.5e-10 41.4 0.3 9.6e-05 23.1 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH19448.1 - 0.0013 18.9 0.0 0.21 11.9 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEH19448.1 - 0.0042 16.1 0.3 0.056 12.4 0.2 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 CEH19448.1 - 0.13 12.3 0.5 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Mito_carr PF00153.27 CEH19450.1 - 1.2e-73 243.1 6.8 2e-22 78.9 0.0 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein tRNA_Me_trans PF03054.16 CEH19451.1 - 1.9e-90 303.3 0.0 7.2e-57 192.8 0.0 3.0 1 1 1 2 2 2 2 tRNA methyl transferase ThiI PF02568.14 CEH19451.1 - 0.018 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 CEH19451.1 - 0.14 11.3 0.6 0.96 8.5 0.1 2.0 2 0 0 2 2 2 0 NAD synthase CBM_21 PF03370.13 CEH19452.1 - 2.9e-30 104.7 0.1 4.7e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CEH19452.1 - 1e-07 32.4 0.3 2.5e-07 31.2 0.3 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) ISAV_HA PF06215.11 CEH19453.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin GSHPx PF00255.19 CEH19454.1 - 2.4e-41 139.7 0.3 3e-41 139.3 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CEH19454.1 - 7.7e-05 22.6 0.2 0.00017 21.5 0.2 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEH19454.1 - 0.00011 21.9 0.1 0.00022 21.0 0.1 1.5 1 1 0 1 1 1 1 Redoxin RNA12 PF10443.9 CEH19455.1 - 1.9e-123 412.5 0.1 3.8e-123 411.5 0.1 1.5 1 1 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 CEH19455.1 - 1.1e-05 25.5 0.0 0.003 17.5 0.0 2.4 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea Fasciclin PF02469.22 CEH19456.1 - 1.5e-56 190.1 0.0 2.4e-17 63.4 0.0 7.7 6 2 0 6 6 6 6 Fasciclin domain DUF4381 PF14316.6 CEH19456.1 - 0.11 12.7 3.1 0.35 11.1 2.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SIP1 PF04938.12 CEH19457.1 - 4.7e-20 72.3 0.0 9e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) zf-C3HC4 PF00097.25 CEH19458.1 - 1.4e-10 40.9 8.2 2.5e-10 40.1 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEH19458.1 - 1.7e-08 34.4 5.0 1.7e-08 34.4 5.0 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CEH19458.1 - 3.1e-08 33.3 4.6 3.1e-08 33.3 4.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEH19458.1 - 6e-08 32.4 6.6 1.1e-07 31.6 3.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEH19458.1 - 9.7e-08 31.9 12.3 2.6e-07 30.5 6.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEH19458.1 - 4e-07 29.9 6.2 4e-07 29.9 6.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 CEH19458.1 - 2.8e-06 27.1 2.0 2.8e-06 27.1 2.0 1.6 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 CEH19458.1 - 1.7e-05 25.1 5.2 1.7e-05 25.1 5.2 2.3 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CEH19458.1 - 0.0069 16.2 8.5 0.12 12.3 5.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEH19458.1 - 0.011 16.0 5.6 0.084 13.2 2.5 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain FYVE PF01363.21 CEH19458.1 - 0.022 14.9 4.8 0.74 10.0 1.9 2.7 2 0 0 2 2 2 0 FYVE zinc finger zf-ANAPC11 PF12861.7 CEH19458.1 - 0.049 13.7 1.6 0.52 10.4 0.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CEH19458.1 - 0.061 13.1 8.7 0.086 12.7 5.6 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain U-box PF04564.15 CEH19458.1 - 0.071 13.3 0.0 0.28 11.4 0.0 2.1 1 0 0 1 1 1 0 U-box domain SAP PF02037.27 CEH19458.1 - 0.087 12.6 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 SAP domain zf-Di19 PF05605.12 CEH19458.1 - 0.087 13.1 0.8 0.76 10.1 0.1 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.6 CEH19458.1 - 0.13 12.2 7.4 2.7 8.0 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-WRNIP1_ubi PF18279.1 CEH19458.1 - 0.26 12.0 0.8 0.71 10.7 0.0 2.2 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C2H2_4 PF13894.6 CEH19458.1 - 0.5 11.3 0.2 0.5 11.3 0.2 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-RING_10 PF16685.5 CEH19458.1 - 0.68 10.1 3.2 1.6 8.9 3.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Mago-bind PF09282.10 CEH19459.1 - 4.4e-14 52.0 1.6 4.4e-14 52.0 1.6 2.0 2 0 0 2 2 2 1 Mago binding Macoilin PF09726.9 CEH19459.1 - 2.8 6.4 8.6 3.6 6.0 8.6 1.1 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 CEH19460.1 - 2.1e-34 119.0 18.9 2.1e-34 119.0 18.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH19460.1 - 3.4e-13 49.3 1.7 3.4e-13 49.3 1.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CEH19460.1 - 1.2e-07 30.5 0.3 1.9e-07 29.9 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pex2_Pex12 PF04757.14 CEH19461.1 - 8.2e-42 143.3 1.6 1e-41 143.0 1.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CEH19461.1 - 1.8e-05 24.5 2.6 2.8e-05 23.9 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEH19461.1 - 0.18 12.1 3.7 0.35 11.2 3.7 1.5 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 CEH19461.1 - 1.3 8.9 4.7 14 5.6 5.1 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEH19461.1 - 1.4 8.8 3.7 2.4 8.1 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEH19461.1 - 2.3 8.1 6.5 9.3 6.2 6.5 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M22 PF00814.25 CEH19462.1 - 3.2e-50 171.4 0.6 5.8e-16 59.0 0.9 4.1 3 1 1 4 4 4 4 Glycoprotease family Senescence PF06911.12 CEH19463.1 - 6.2e-39 134.2 1.9 9.6e-39 133.6 1.9 1.3 1 0 0 1 1 1 1 Senescence-associated protein DIOX_N PF14226.6 CEH19464.1 - 6.9e-25 88.1 0.0 9.6e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CEH19464.1 - 2.7e-15 56.7 0.0 6.4e-15 55.5 0.0 1.7 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily SUR7 PF06687.12 CEH19465.1 - 1.6e-19 70.4 5.7 1.9e-19 70.1 5.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 CEH19465.1 - 0.013 15.2 3.2 0.011 15.5 1.8 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MFS_1 PF07690.16 CEH19466.1 - 9.4e-25 87.3 36.5 1.4e-19 70.2 17.5 3.1 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH19466.1 - 2.9e-06 26.4 0.4 2.9e-06 26.4 0.4 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TssN PF17555.2 CEH19466.1 - 0.04 13.3 0.4 0.068 12.5 0.4 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN Tetraspanin PF00335.20 CEH19466.1 - 0.5 10.0 1.9 2.3 7.9 0.3 2.4 2 0 0 2 2 2 0 Tetraspanin family MARVEL PF01284.23 CEH19466.1 - 2.8 8.0 24.3 0.97 9.5 0.0 3.9 4 1 0 4 4 4 0 Membrane-associating domain ADH_zinc_N PF00107.26 CEH19467.1 - 1.4e-18 67.1 0.4 2.4e-18 66.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEH19467.1 - 5.9e-08 33.8 0.1 1.3e-07 32.8 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 CEH19467.1 - 7.7e-05 22.2 0.2 0.00013 21.5 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEH19467.1 - 0.005 16.4 0.1 0.01 15.4 0.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 CEH19467.1 - 0.008 16.0 0.0 0.024 14.5 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 CEH19467.1 - 0.076 13.2 0.6 0.24 11.6 0.3 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF459 PF04311.13 CEH19467.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) LRR_6 PF13516.6 CEH19468.1 - 3e-08 33.1 8.6 1.2 9.4 0.1 6.8 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 CEH19468.1 - 0.008 16.6 10.4 5.2 7.6 0.3 4.8 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEH19468.1 - 0.58 10.9 5.1 52 5.0 0.0 5.2 7 0 0 7 7 7 0 Leucine Rich Repeat eIF3g PF12353.8 CEH19469.1 - 8.2e-43 145.8 3.4 1.4e-42 145.0 3.4 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CEH19469.1 - 2.2e-20 72.2 0.0 3.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEH19469.1 - 0.00028 20.9 1.5 0.15 12.2 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif PHM7_cyt PF14703.6 CEH19469.1 - 0.026 14.8 0.8 8.2 6.6 0.0 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 CEH19469.1 - 0.18 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SPOR PF05036.13 CEH19469.1 - 0.22 12.0 0.8 1.1 9.7 0.0 2.5 3 0 0 3 3 3 0 Sporulation related domain GLTP PF08718.11 CEH19470.1 - 6.5e-48 162.8 0.0 8.4e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) IRF-2BP1_2 PF11261.8 CEH19471.1 - 0.079 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger LrgB PF04172.16 CEH19472.1 - 7e-41 140.1 11.1 7e-41 140.1 11.1 2.0 2 0 0 2 2 2 1 LrgB-like family CcmD PF04995.14 CEH19472.1 - 0.00096 19.2 0.4 0.0049 16.9 0.0 2.5 2 0 0 2 2 2 1 Heme exporter protein D (CcmD) muHD PF10291.9 CEH19473.1 - 2.8e-54 184.3 0.0 4.5e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 CEH19473.1 - 1.2e-05 25.5 1.2 5.3e-05 23.4 1.2 2.1 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain AATF-Che1 PF13339.6 CEH19473.1 - 0.31 11.7 5.9 0.7 10.6 5.9 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor ORF_12_N PF18042.1 CEH19473.1 - 8.2 6.9 6.6 2.9 8.4 0.7 3.2 3 1 0 3 3 3 0 ORF 12 gene product N-terminal Cutinase PF01083.22 CEH19474.1 - 7.4e-22 78.2 0.2 1.3e-21 77.4 0.2 1.4 1 0 0 1 1 1 1 Cutinase PEPCK_ATP PF01293.20 CEH19476.1 - 1.6e-217 722.7 0.0 2e-217 722.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 CEH19476.1 - 0.0073 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEH19476.1 - 0.0088 16.4 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CEH19476.1 - 0.04 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 CEH19478.1 - 3.9e-41 140.6 0.0 9e-41 139.4 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEH19478.1 - 2.2e-06 27.4 0.1 5e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CEH19478.1 - 6.6e-05 22.9 0.0 0.00022 21.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEH19478.1 - 7.9e-05 22.9 0.0 0.005 17.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 CEH19478.1 - 0.00023 21.3 0.0 0.00068 19.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CEH19478.1 - 0.0007 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 CEH19478.1 - 0.0016 18.9 0.1 0.023 15.1 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CEH19478.1 - 0.0087 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CEH19478.1 - 0.0088 16.3 0.0 0.027 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEH19478.1 - 0.016 14.7 0.0 0.039 13.5 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CEH19478.1 - 0.02 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CEH19478.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 CEH19478.1 - 0.075 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CEH19478.1 - 0.076 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CEH19478.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CEH19478.1 - 0.089 13.3 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CEH19478.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 CEH19478.1 - 0.16 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CEH19478.1 - 0.16 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CEH19478.1 - 0.19 11.4 0.1 0.95 9.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain TraT PF05818.12 CEH19478.1 - 0.54 9.9 2.7 0.85 9.3 2.7 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Exo_endo_phos PF03372.23 CEH19479.1 - 5.8e-07 29.3 0.4 1e-06 28.5 0.4 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 CEH19479.1 - 1.6e-06 28.1 13.6 4.5e-06 26.6 9.3 3.1 2 1 0 2 2 2 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 CEH19479.1 - 0.00099 18.9 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase F-box-like PF12937.7 CEH19480.1 - 3.3e-07 30.1 1.0 7.5e-07 28.9 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEH19480.1 - 1.7e-06 27.7 0.4 3.4e-06 26.8 0.4 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 CEH19480.1 - 3.9e-05 24.3 3.7 28 5.8 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box_4 PF15966.5 CEH19480.1 - 0.0071 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 F-box PQQ_3 PF13570.6 CEH19480.1 - 0.086 13.4 0.3 2.4 8.8 0.0 3.2 1 1 1 2 2 2 0 PQQ-like domain SH3_9 PF14604.6 CEH19481.1 - 5.8e-10 38.9 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEH19481.1 - 3.1e-07 29.9 0.0 5.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.11 CEH19481.1 - 0.015 15.4 0.6 0.015 15.4 0.6 1.8 2 0 0 2 2 2 0 Podoplanin MAGI_u5 PF16666.5 CEH19482.1 - 0.28 11.3 6.6 0.32 11.2 6.6 1.1 1 0 0 1 1 1 0 Unstructured region on MAGI PIF PF05092.12 CEH19483.1 - 0.042 12.6 0.0 0.055 12.2 0.0 1.1 1 0 0 1 1 1 0 Per os infectivity DUF2663 PF10864.8 CEH19485.1 - 0.14 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) LapA_dom PF06305.11 CEH19485.1 - 0.43 10.4 0.1 0.43 10.4 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RasGEF PF00617.19 CEH19486.1 - 1.8e-46 158.5 0.0 3.4e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CEH19486.1 - 1.3e-20 73.6 0.1 2.4e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.17 CEH19486.1 - 9.9e-13 47.6 0.0 1.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEH19486.1 - 1.5e-12 46.9 0.0 2.8e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEH19486.1 - 2e-12 46.8 0.0 3.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain IKI3 PF04762.12 CEH19486.1 - 0.23 9.4 0.0 0.34 8.8 0.0 1.1 1 0 0 1 1 1 0 IKI3 family GTP1_OBG PF01018.22 CEH19489.1 - 1.3e-34 119.0 2.7 3.4e-26 91.7 2.1 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 CEH19489.1 - 1.3e-19 70.3 0.0 6.2e-19 68.2 0.0 2.1 2 1 1 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEH19489.1 - 0.00017 21.1 0.0 0.021 14.4 0.0 3.0 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CEH19489.1 - 0.00021 20.9 0.0 0.024 14.2 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CEH19489.1 - 0.00044 20.3 0.0 0.15 12.1 0.0 3.0 3 0 0 3 3 3 1 Dynamin family Arf PF00025.21 CEH19489.1 - 0.002 17.6 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family ABC_tran PF00005.27 CEH19489.1 - 0.018 15.6 0.3 0.057 13.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NOG1 PF06858.14 CEH19489.1 - 0.02 14.7 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) cobW PF02492.19 CEH19489.1 - 0.061 12.9 0.0 6.9 6.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CEH19489.1 - 0.075 13.3 0.0 6.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SUI1 PF01253.22 CEH19490.1 - 1e-17 64.4 0.0 4.4e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CEH19490.1 - 1.5e-10 41.6 1.0 3.4e-10 40.5 0.0 2.2 2 1 0 2 2 2 1 Pre-PUA-like domain SWIB PF02201.18 CEH19490.1 - 0.0051 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain CLTH PF10607.9 CEH19492.1 - 2.8e-15 56.5 0.0 5e-15 55.7 0.0 1.4 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40 PF00400.32 CEH19493.1 - 3.9e-38 128.8 11.5 4.4e-08 33.7 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEH19493.1 - 3e-13 49.9 0.0 4.6e-05 23.6 0.0 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CEH19493.1 - 0.001 17.7 0.0 0.13 10.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 CEH19493.1 - 0.0023 17.8 0.0 0.42 10.5 0.0 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 CEH19493.1 - 0.0069 16.0 0.0 0.48 10.0 0.0 2.9 2 1 0 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 CEH19493.1 - 0.09 11.7 0.5 8.3 5.3 0.1 2.8 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 CEH19493.1 - 8.3 6.2 8.9 3.4 7.4 0.1 3.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Tmemb_170 PF10190.9 CEH19494.1 - 0.0084 16.5 1.0 0.019 15.4 1.0 1.5 1 0 0 1 1 1 1 Putative transmembrane protein 170 T3SS_needle_F PF09392.10 CEH19494.1 - 0.038 14.2 0.1 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF883 PF05957.13 CEH19494.1 - 0.048 14.3 0.9 0.14 12.8 0.9 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Rho_N PF07498.12 CEH19494.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain RNase_T PF00929.24 CEH19496.1 - 1.5e-10 41.9 0.0 3.3e-07 31.0 0.0 2.9 3 0 0 3 3 3 2 Exonuclease SAP PF02037.27 CEH19496.1 - 4.4e-08 32.7 0.6 9.8e-08 31.6 0.2 1.7 2 0 0 2 2 2 1 SAP domain Semialdhyde_dhC PF02774.18 CEH19497.1 - 2.3e-38 132.1 0.2 5.5e-38 130.9 0.1 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CEH19497.1 - 1.1e-27 96.9 0.0 2.1e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CEH19497.1 - 0.066 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.20 CEH19497.1 - 0.17 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain MbtH PF03621.13 CEH19498.1 - 0.066 12.7 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 MbtH-like protein UCH PF00443.29 CEH19499.1 - 1.9e-44 152.1 0.0 2.6e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEH19499.1 - 1.2e-11 44.8 3.7 3.7e-07 30.1 0.7 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CEH19499.1 - 2.9e-08 33.4 0.0 7.4e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 CEH19499.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Nop25 PF09805.9 CEH19499.1 - 0.45 11.0 10.4 0.25 11.8 5.1 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) YL1 PF05764.13 CEH19500.1 - 1.8e-39 136.3 14.6 1.8e-39 136.3 14.6 1.5 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 CEH19500.1 - 3.4e-13 49.1 0.8 5.7e-13 48.4 0.8 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain MFS_1 PF07690.16 CEH19501.1 - 2.4e-37 128.7 67.0 1.5e-33 116.3 44.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEH19501.1 - 2.7e-09 36.4 6.4 2.7e-09 36.4 6.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter A_deaminase PF00962.22 CEH19502.1 - 7.1e-118 393.7 0.1 1.1e-117 393.1 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Methyltransf_16 PF10294.9 CEH19503.1 - 1e-16 61.2 0.0 1.7e-15 57.2 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 CEH19503.1 - 0.029 15.1 0.2 0.12 13.1 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CEH19503.1 - 0.068 13.0 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CEH19503.1 - 0.14 12.9 0.1 0.57 11.0 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain E1-E2_ATPase PF00122.20 CEH19504.1 - 3.2e-50 170.2 8.0 4.7e-50 169.6 2.7 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEH19504.1 - 6.5e-44 149.8 4.0 1.2e-43 149.0 1.3 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CEH19504.1 - 1.4e-25 90.8 3.7 4.1e-25 89.3 0.6 3.1 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEH19504.1 - 2.3e-21 75.2 0.1 6.1e-21 73.9 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEH19504.1 - 1.9e-15 56.7 0.0 3.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 CEH19504.1 - 2.8e-06 27.9 0.0 1e-05 26.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CEH19504.1 - 0.00017 21.4 1.7 0.001 18.9 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Galactosyl_T PF01762.21 CEH19505.1 - 5e-08 33.0 0.3 3.5e-05 23.7 0.0 2.9 2 1 1 3 3 3 2 Galactosyltransferase KH_6 PF15985.5 CEH19506.1 - 3.3e-11 43.4 0.0 1.1e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 CEH19506.1 - 1.2e-07 31.4 0.1 2.2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Arrestin_C PF02752.22 CEH19508.1 - 1.8e-14 54.3 0.0 4.6e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEH19508.1 - 0.0056 16.7 0.2 4.3 7.4 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Peptidase_M24 PF00557.24 CEH19510.1 - 2.1e-37 128.9 0.0 3.3e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 CEH19510.1 - 1.2e-31 110.0 0.0 3.8e-30 105.1 0.0 2.8 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 CEH19510.1 - 8.3e-18 65.3 0.0 2.1e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CEH19510.1 - 2e-15 56.6 0.2 2.6e-14 53.0 0.7 2.7 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 ATP-synt_ab PF00006.25 CEH19511.1 - 4e-106 353.4 0.0 5.8e-106 352.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CEH19511.1 - 8.7e-43 145.0 0.0 1.5e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CEH19511.1 - 4.8e-15 55.8 3.3 1.3e-14 54.4 3.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain zf-HIT PF04438.16 CEH19512.1 - 5.4e-09 35.8 11.0 8.9e-09 35.1 11.0 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 CEH19512.1 - 3.1 8.0 14.4 6 7.0 14.4 1.5 1 0 0 1 1 1 0 MYND finger TP_methylase PF00590.20 CEH19513.1 - 1.5e-17 64.3 2.3 1.9e-17 63.9 0.2 2.2 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases HypD PF01924.16 CEH19513.1 - 0.087 11.9 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase formation hypA family Abhydrolase_1 PF00561.20 CEH19514.1 - 5.6e-21 75.3 0.5 2.3e-19 70.1 0.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEH19514.1 - 1.9e-13 51.5 0.4 4.1e-13 50.4 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH19514.1 - 5.1e-12 45.6 0.3 1.5e-11 44.0 0.2 1.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 CMD PF02627.20 CEH19514.1 - 6.4e-08 32.5 0.8 4.3e-07 29.9 0.0 2.7 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Peptidase_S9 PF00326.21 CEH19514.1 - 0.0026 17.3 0.5 0.25 10.8 0.0 3.0 2 2 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 CEH19514.1 - 0.014 15.0 0.3 0.034 13.8 0.3 1.7 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 CEH19514.1 - 0.021 14.7 0.0 0.066 13.0 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 CEH19514.1 - 0.033 14.1 0.1 0.17 11.8 0.1 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 CEH19514.1 - 0.056 13.5 0.3 0.17 11.9 0.1 1.8 2 1 0 2 2 2 0 Thioesterase domain DUF2236 PF09995.9 CEH19515.1 - 1.6e-11 44.9 0.7 1.6e-11 44.9 0.7 1.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Mito_carr PF00153.27 CEH19516.1 - 4.1e-37 126.0 8.3 5.2e-16 58.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MCU PF04678.13 CEH19517.1 - 1.1e-26 94.1 0.3 1.1e-26 94.1 0.3 2.2 2 1 0 2 2 2 1 Mitochondrial calcium uniporter DUF2839 PF10999.8 CEH19517.1 - 0.18 12.2 0.0 0.18 12.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) UQ_con PF00179.26 CEH19519.1 - 1.8e-20 73.0 0.0 3.2e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CEH19519.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain UBA PF00627.31 CEH19519.1 - 0.041 13.8 3.9 0.048 13.6 1.9 2.3 2 0 0 2 2 2 0 UBA/TS-N domain IBR PF01485.21 CEH19519.1 - 4.3 7.6 6.9 4.6 7.5 5.4 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Glyco_hydro_cc PF11790.8 CEH19521.1 - 5.1e-28 98.2 0.0 7.6e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core GvpL_GvpF PF06386.11 CEH19522.1 - 0.04 13.8 0.0 0.04 13.8 0.0 2.5 2 1 1 3 3 3 0 Gas vesicle synthesis protein GvpL/GvpF zf-RanBP PF00641.18 CEH19523.1 - 3.8e-06 26.1 13.8 0.0053 16.0 1.6 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 CEH19523.1 - 0.12 12.4 3.6 0.79 9.8 0.2 2.7 2 0 0 2 2 2 0 Double zinc ribbon Thioredoxin PF00085.20 CEH19524.1 - 2.8e-58 194.3 1.8 6.6e-28 96.7 0.1 3.7 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CEH19524.1 - 6.6e-37 127.2 1.2 1.9e-31 109.4 0.1 3.5 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CEH19524.1 - 3.1e-07 30.5 0.1 0.0046 17.1 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CEH19524.1 - 6.2e-07 29.9 0.8 0.015 15.8 0.1 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CEH19524.1 - 6.7e-07 28.9 0.0 0.015 14.7 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CEH19524.1 - 3e-06 27.5 0.1 0.049 14.0 0.0 3.8 4 1 1 5 5 5 2 Thioredoxin-like Calsequestrin PF01216.17 CEH19524.1 - 3e-05 23.2 2.6 4.9e-05 22.5 2.6 1.3 1 0 0 1 1 1 1 Calsequestrin Redoxin PF08534.10 CEH19524.1 - 0.0025 17.5 1.4 0.11 12.2 0.1 2.9 3 0 0 3 3 3 1 Redoxin AhpC-TSA PF00578.21 CEH19524.1 - 0.008 16.1 0.7 0.56 10.1 0.0 3.0 2 1 1 3 3 3 1 AhpC/TSA family TraF PF13728.6 CEH19524.1 - 0.12 12.1 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein PWI PF01480.17 CEH19525.1 - 8.2e-08 32.5 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 CEH19525.1 - 4.5e-07 29.8 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CEH19525.1 - 6.6e-07 29.1 0.0 5e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 CEH19525.1 - 1.2e-06 28.2 4.4 2.4e-06 27.3 4.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEH19525.1 - 0.00031 20.7 6.7 0.00066 19.7 6.7 1.6 1 0 0 1 1 1 1 Zinc finger domain RRM_3 PF08777.11 CEH19525.1 - 0.015 15.3 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif DUF1631 PF07793.11 CEH19525.1 - 0.041 12.3 0.1 0.041 12.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) PRKG1_interact PF15898.5 CEH19525.1 - 0.37 11.7 4.4 0.86 10.5 4.4 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain T3SSipB PF16535.5 CEH19525.1 - 0.83 10.1 6.3 2.1 8.8 6.3 1.7 1 0 0 1 1 1 0 Type III cell invasion protein SipB LCAT PF02450.15 CEH19526.1 - 3.8e-10 39.5 0.0 7.9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CEH19526.1 - 3.4e-06 27.8 0.1 1.3e-05 25.9 0.1 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH19526.1 - 3.2e-05 23.3 0.0 7.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH19526.1 - 0.00023 20.9 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 CEH19526.1 - 0.00078 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 CEH19526.1 - 0.0037 17.0 0.2 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Putative esterase DUF900 PF05990.12 CEH19526.1 - 0.004 16.7 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 CEH19526.1 - 0.062 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase DUF676 PF05057.14 CEH19526.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) EphA2_TM PF14575.6 CEH19527.1 - 0.0037 18.1 0.0 0.0086 16.9 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain YLP PF02757.17 CEH19527.1 - 0.045 13.7 0.7 0.2 11.7 0.7 2.2 1 0 0 1 1 1 0 YLP motif DUF4381 PF14316.6 CEH19527.1 - 0.11 12.7 0.3 0.27 11.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DEAD PF00270.29 CEH19528.1 - 3.2e-37 128.0 0.0 9.3e-36 123.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH19528.1 - 3.8e-18 65.8 0.0 5.6e-17 62.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CEH19528.1 - 0.0027 17.0 0.0 0.0054 16.0 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CEH19528.1 - 0.068 13.2 1.0 1.3 9.0 0.0 3.1 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit Spem1 PF15670.5 CEH19528.1 - 0.11 12.1 0.2 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Spermatid maturation protein 1 DAHP_synth_2 PF01474.16 CEH19529.1 - 3.8e-183 609.0 0.0 4.4e-183 608.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family MIP PF00230.20 CEH19530.1 - 3.5e-43 147.9 7.9 4.4e-43 147.6 7.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein TALPID3 PF15324.6 CEH19532.1 - 1.4 6.5 3.5 2 6.0 3.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Med12 PF09497.10 CEH19533.1 - 1.5e-24 86.0 0.1 4e-24 84.7 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 EMP70 PF02990.16 CEH19534.1 - 1.1e-184 615.0 0.1 1.3e-184 614.8 0.1 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 ApbA_C PF08546.11 CEH19536.1 - 8.5e-22 77.7 0.0 1.3e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CEH19536.1 - 4.4e-21 75.1 0.0 6.2e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.21 CEH19536.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase E3_binding PF02817.17 CEH19536.1 - 0.02 15.2 1.0 15 6.1 0.1 4.1 4 0 0 4 4 4 0 e3 binding domain 2-Hacid_dh_C PF02826.19 CEH19536.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain COX5A PF02284.16 CEH19537.1 - 1.5e-40 137.3 0.1 1.9e-40 137.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va NTase_sub_bind PF08780.11 CEH19537.1 - 0.052 13.5 0.1 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like V_ATPase_I PF01496.19 CEH19538.1 - 0 1028.7 0.0 0 1028.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ATG16 PF08614.11 CEH19538.1 - 0.025 14.8 0.5 0.081 13.1 0.0 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF2427 PF10348.9 CEH19538.1 - 2 8.3 8.3 0.55 10.0 2.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) Amino_oxidase PF01593.24 CEH19540.1 - 3.2e-32 112.4 0.1 4.4e-32 112.0 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEH19540.1 - 7.6e-05 22.9 0.1 0.0002 21.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CEH19540.1 - 0.0039 16.5 0.1 0.0061 15.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEH19540.1 - 0.028 13.7 0.3 0.045 13.0 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 CEH19540.1 - 0.22 10.7 0.1 0.41 9.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 CEH19543.1 - 3.7e-31 108.4 36.4 5.1e-31 107.9 36.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PAF-AH_p_II PF03403.13 CEH19544.1 - 1.8e-36 125.5 0.0 2.8e-17 62.3 0.0 4.3 4 1 0 4 4 4 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 CEH19544.1 - 0.0025 16.8 0.0 0.027 13.4 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 CEH19544.1 - 0.013 16.1 1.2 0.013 16.1 1.2 2.1 2 1 1 3 3 3 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEH19544.1 - 0.017 14.4 0.1 1.7 7.9 0.1 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH19544.1 - 0.033 13.8 0.0 0.097 12.3 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 CEH19544.1 - 0.039 12.9 0.0 0.28 10.2 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase RuBisCO_large PF00016.20 CEH19544.1 - 0.045 13.0 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Nop10p PF04135.12 CEH19545.1 - 2.1e-21 75.7 0.2 2.4e-21 75.5 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF3413 PF11893.8 CEH19546.1 - 0.00025 20.3 1.2 0.00025 20.3 1.2 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3413) HCV_capsid PF01543.17 CEH19548.1 - 0.059 13.6 3.6 1.4 9.1 0.9 3.5 2 0 0 2 2 2 0 Hepatitis C virus capsid protein MFS_1 PF07690.16 CEH19549.1 - 5.4e-29 101.2 39.0 1.7e-28 99.6 39.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Rad10 PF03834.14 CEH19551.1 - 3.7e-45 152.6 0.0 5.2e-45 152.1 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.7 CEH19551.1 - 0.00016 21.7 0.0 0.0052 16.9 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CEH19551.1 - 0.00023 21.7 0.1 0.0011 19.5 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain UIM PF02809.20 CEH19551.1 - 0.021 14.7 0.5 0.021 14.7 0.5 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif RAP80_UIM PF18282.1 CEH19551.1 - 0.11 12.3 0.5 0.77 9.6 0.6 2.3 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif ER-remodelling PF14755.6 CEH19551.1 - 1.1 9.6 14.7 1.6 9.0 12.8 2.2 2 0 0 2 2 2 0 Intracellular membrane remodeller NCA2 PF08637.10 CEH19552.1 - 2.5e-80 269.8 1.7 2.5e-80 269.8 1.7 1.8 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 FAA_hydro_N_2 PF18288.1 CEH19552.1 - 0.11 12.9 1.0 4.7 7.7 0.0 3.5 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 BCNT PF07572.12 CEH19553.1 - 3.9e-15 55.7 0.0 9.2e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUF4578 PF15147.6 CEH19553.1 - 7.4 7.5 6.1 39 5.1 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) IMS PF00817.20 CEH19554.1 - 3.7e-38 130.9 0.1 1.9e-37 128.6 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family REV1_C PF16727.5 CEH19554.1 - 2.2e-16 60.0 0.2 2.2e-16 60.0 0.2 2.0 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 CEH19554.1 - 1.7e-12 46.3 10.8 4e-05 22.9 0.5 3.9 3 0 0 3 3 3 3 Ubiquitin binding region IMS_C PF11799.8 CEH19554.1 - 1e-11 45.6 0.0 2.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 CEH19554.1 - 2.6e-09 37.4 0.0 5.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CEH19554.1 - 3.7e-05 23.9 0.0 7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 CEH19554.1 - 0.0026 18.1 0.0 0.0053 17.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain mCpol PF18182.1 CEH19554.1 - 0.19 12.1 0.1 0.56 10.6 0.0 1.8 2 0 0 2 2 2 0 minimal CRISPR polymerase domain 2Fe-2S_thioredx PF01257.19 CEH19555.1 - 5.1e-60 201.5 0.0 6.4e-60 201.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Homeodomain PF00046.29 CEH19556.1 - 2.3e-14 53.0 1.9 5.3e-14 51.8 1.9 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEH19556.1 - 0.00043 20.1 0.1 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain BLOC1S3 PF15753.5 CEH19556.1 - 0.25 11.5 4.6 0.32 11.1 0.9 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 ACPS PF01648.20 CEH19557.1 - 2.2e-12 47.1 0.0 2.8e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily FANCM-MHF_bd PF16783.5 CEH19557.1 - 0.12 12.4 1.4 0.6 10.2 0.2 2.1 2 0 0 2 2 2 0 FANCM to MHF binding domain Peptidase_S9 PF00326.21 CEH19558.1 - 4.4e-33 114.5 0.0 9.3e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PIG-H PF10181.9 CEH19558.1 - 4.2e-11 42.5 0.0 9.4e-11 41.4 0.0 1.6 1 1 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DLH PF01738.18 CEH19558.1 - 3.4e-07 30.0 0.0 7.2e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 CEH19558.1 - 0.00054 19.3 0.0 0.22 10.7 0.0 2.7 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEH19558.1 - 0.0081 15.8 0.2 13 5.3 0.0 3.2 2 1 1 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.20 CEH19558.1 - 0.0092 15.7 0.1 0.022 14.4 0.1 1.6 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 CEH19558.1 - 0.015 15.2 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 CEH19558.1 - 0.015 15.2 0.0 0.81 9.5 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.13 CEH19558.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) COesterase PF00135.28 CEH19558.1 - 0.13 11.1 0.0 1.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family AXE1 PF05448.12 CEH19558.1 - 0.17 10.5 0.0 0.97 8.0 0.0 2.2 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) LIP PF03583.14 CEH19558.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_2 PF02230.16 CEH19558.1 - 0.21 11.4 0.0 13 5.6 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase TFIIA_gamma_N PF02268.16 CEH19559.1 - 4.1e-25 87.5 0.1 5.9e-25 87.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 CEH19559.1 - 1.1e-18 67.1 0.0 1.8e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TetR_C_28 PF17937.1 CEH19561.1 - 0.045 14.2 0.3 6.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ABC2_membrane_4 PF12730.7 CEH19561.1 - 5.3 7.0 7.0 1.5 8.7 0.3 2.7 3 0 0 3 3 3 0 ABC-2 family transporter protein Sporozoite_P67 PF05642.11 CEH19562.1 - 0.0018 16.5 0.1 0.0018 16.5 0.1 5.3 2 2 3 5 5 5 1 Sporozoite P67 surface antigen GPI-anchored PF10342.9 CEH19564.1 - 1.3e-10 41.9 2.1 3e-10 40.7 2.1 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family adh_short PF00106.25 CEH19566.1 - 2.4e-19 69.6 0.9 1.6e-08 34.2 0.0 4.0 2 2 2 4 4 4 3 short chain dehydrogenase adh_short_C2 PF13561.6 CEH19566.1 - 2.8e-11 43.5 3.0 3.9e-06 26.6 0.3 4.0 3 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEH19566.1 - 3.3e-05 23.9 1.1 0.013 15.4 0.1 2.3 2 0 0 2 2 2 2 KR domain BatA PF07584.11 CEH19566.1 - 0.47 10.9 8.5 0.28 11.6 2.8 2.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF2849 PF11011.8 CEH19567.1 - 0.12 13.0 0.1 0.12 13.0 0.1 4.1 6 0 0 6 6 6 0 Protein of unknown function (DUF2849) BUD22 PF09073.10 CEH19568.1 - 1.6e-56 192.5 56.5 1.6e-56 192.5 56.5 2.4 2 1 0 2 2 2 1 BUD22 Lumazine_bd_2 PF12893.7 CEH19568.1 - 0.11 13.2 0.1 0.35 11.6 0.1 1.8 1 0 0 1 1 1 0 Putative lumazine-binding Ima1_N PF09779.9 CEH19569.1 - 8.9e-19 68.7 2.8 4.9e-18 66.3 2.8 2.2 1 1 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 CEH19569.1 - 0.31 11.1 2.9 3.7 7.7 0.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon Complex1_LYR PF05347.15 CEH19570.1 - 5.7e-08 32.7 5.0 1.1e-07 31.8 5.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ILVD_EDD PF00920.21 CEH19571.1 - 1.1e-202 674.2 0.1 1.3e-202 674.0 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family DAO PF01266.24 CEH19572.1 - 3.4e-51 174.9 0.4 6.4e-51 174.0 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CEH19572.1 - 1.5e-43 147.6 0.1 3e-43 146.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 CEH19572.1 - 2.5e-07 31.0 0.1 5.7e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.24 CEH19572.1 - 1.1e-05 24.7 4.8 2.8e-05 23.4 3.8 2.2 2 1 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 CEH19572.1 - 8.2e-05 22.1 0.3 8.2e-05 22.1 0.3 1.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase EF-hand_6 PF13405.6 CEH19572.1 - 0.0002 21.0 6.0 0.00074 19.3 0.1 3.0 3 0 0 3 3 2 1 EF-hand domain EF-hand_8 PF13833.6 CEH19572.1 - 0.00025 20.8 0.1 0.00025 20.8 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CEH19572.1 - 0.0018 17.7 4.1 0.015 14.8 0.0 3.3 3 0 0 3 3 3 1 EF hand NAD_binding_8 PF13450.6 CEH19572.1 - 0.005 17.0 0.4 0.039 14.2 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CEH19572.1 - 0.0073 15.4 0.2 0.11 11.6 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CEH19572.1 - 0.0091 15.3 0.1 0.038 13.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEH19572.1 - 0.01 15.1 1.2 0.11 11.7 1.2 2.1 1 1 0 1 1 1 0 FAD binding domain EF-hand_5 PF13202.6 CEH19572.1 - 0.062 12.8 0.1 0.062 12.8 0.1 2.2 2 0 0 2 2 2 0 EF hand Dockerin_1 PF00404.18 CEH19572.1 - 0.084 13.1 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Dockerin type I domain HI0933_like PF03486.14 CEH19572.1 - 0.099 11.3 1.2 0.17 10.6 1.2 1.3 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 CEH19572.1 - 0.12 12.2 0.2 0.27 11.1 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 CEH19572.1 - 0.13 11.5 0.1 0.37 10.0 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEH19572.1 - 0.23 12.1 0.8 0.58 10.8 0.8 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-C2H2_2 PF12756.7 CEH19573.1 - 8.3e-32 109.5 0.6 2.5e-26 91.9 0.1 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CEH19573.1 - 1.5e-09 37.9 4.3 5.5e-08 32.9 3.0 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEH19573.1 - 8e-05 22.9 6.4 0.00049 20.4 2.2 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CEH19573.1 - 0.0004 21.0 10.0 0.15 12.9 0.3 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEH19573.1 - 0.31 11.1 6.8 1.7 8.7 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger GILT PF03227.16 CEH19574.1 - 4.4e-14 52.6 0.0 7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Stevor PF17410.2 CEH19574.1 - 0.075 12.6 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame peroxidase PF00141.23 CEH19575.1 - 3.5e-46 157.8 0.0 4.9e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Mito_carr PF00153.27 CEH19576.1 - 2.9e-56 187.4 2.3 1.6e-18 66.4 0.1 4.1 4 0 0 4 4 4 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEH19576.1 - 0.0018 17.5 0.1 0.64 9.1 0.0 3.6 4 0 0 4 4 4 1 Gammaproteobacterial serine protease DHHC PF01529.20 CEH19577.1 - 6.7e-35 120.1 8.5 6.7e-35 120.1 8.5 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Evr1_Alr PF04777.13 CEH19578.1 - 8e-27 93.6 0.0 1.1e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family FGGY_N PF00370.21 CEH19581.1 - 5.9e-66 222.5 0.2 7.7e-66 222.1 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CEH19581.1 - 4.3e-64 215.9 1.2 9.6e-64 214.8 1.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain RNB PF00773.19 CEH19582.1 - 2.5e-71 240.7 2.4 3.8e-61 207.2 0.1 2.2 1 1 1 2 2 2 2 RNB domain Rrp44_S1 PF17215.3 CEH19582.1 - 3.5e-21 75.0 0.1 7.9e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 CEH19582.1 - 4.4e-16 58.7 0.0 1e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CEH19582.1 - 6.2e-13 48.7 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain PIN_4 PF13638.6 CEH19582.1 - 2.8e-09 37.3 0.0 1e-08 35.5 0.0 2.0 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 CEH19582.1 - 5.8e-06 26.4 0.0 0.00098 19.2 0.0 3.0 3 0 0 3 3 3 1 Cold shock domain OB_RNB PF08206.11 CEH19582.1 - 0.19 11.4 1.2 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain NIF PF03031.18 CEH19584.1 - 7.3e-54 181.8 0.0 9.8e-54 181.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TctA PF01970.16 CEH19584.1 - 0.48 9.1 0.7 0.76 8.4 0.7 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family CENP-B_dimeris PF09026.10 CEH19584.1 - 0.78 10.2 10.7 2.2 8.7 10.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_L14 PF00238.19 CEH19585.1 - 5.8e-45 152.3 2.1 6.7e-45 152.1 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PIN_4 PF13638.6 CEH19586.1 - 7.1e-20 71.6 0.0 1.2e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 PIN domain DEAD PF00270.29 CEH19587.1 - 1.2e-19 70.8 0.0 2.2e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEH19587.1 - 6.8e-16 58.6 0.0 5.4e-14 52.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CEH19587.1 - 6.3e-09 36.4 0.1 1.5e-08 35.2 0.1 1.7 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 CEH19587.1 - 5.6e-06 26.5 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CTP_transf_1 PF01148.20 CEH19587.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family AAA_16 PF13191.6 CEH19588.1 - 1.6e-06 28.6 1.5 2.4e-06 28.0 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 CEH19588.1 - 0.0014 18.3 0.1 0.0077 15.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 CEH19588.1 - 0.0042 16.8 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CEH19588.1 - 0.0064 16.8 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 CEH19588.1 - 0.036 13.0 0.3 0.13 11.1 0.0 1.9 2 1 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Asp_Glu_race PF01177.22 CEH19588.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase T2SSE PF00437.20 CEH19588.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 CEH19588.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 CEH19588.1 - 0.16 12.3 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain SCO1-SenC PF02630.14 CEH19589.1 - 2.8e-41 140.6 0.0 4.7e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC CAP_GLY PF01302.25 CEH19589.1 - 9.5e-24 83.2 0.7 1.9e-23 82.3 0.7 1.5 1 0 0 1 1 1 1 CAP-Gly domain AhpC-TSA PF00578.21 CEH19589.1 - 0.0093 15.9 0.0 0.042 13.8 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family MAP65_ASE1 PF03999.12 CEH19589.1 - 1.1 7.9 2.1 1.4 7.5 2.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4336 PF14234.6 CEH19590.1 - 2.4e-09 36.8 0.1 0.0002 20.7 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Secretin_N PF03958.17 CEH19592.1 - 0.028 14.8 0.1 0.039 14.4 0.1 1.6 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain TFIIE_alpha PF02002.17 CEH19593.1 - 4.1e-15 55.5 0.0 9.1e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TRAPP PF04051.16 CEH19594.1 - 5.1e-32 110.6 0.0 8.3e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SWIB PF02201.18 CEH19595.1 - 5.9e-23 80.6 0.0 8.9e-23 80.0 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain COX7C PF02935.16 CEH19596.1 - 7.3e-15 55.0 0.4 7.9e-15 54.9 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Brix PF04427.18 CEH19597.1 - 8.2e-19 68.5 0.0 1.3e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Brix domain LAT PF15234.6 CEH19597.1 - 0.032 14.0 2.2 0.071 12.8 2.2 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells Cas_Csy4 PF09618.10 CEH19597.1 - 0.14 12.3 4.2 0.32 11.1 4.2 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) RSN1_7TM PF02714.15 CEH19599.1 - 1.6e-35 122.8 25.5 2.3e-35 122.2 25.5 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CEH19599.1 - 4.6e-18 66.1 0.1 2.2e-13 50.8 0.0 2.9 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CEH19599.1 - 2.7e-13 50.0 2.7 2.7e-13 50.0 2.7 3.1 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport Phage_holin_4_2 PF04020.13 CEH19599.1 - 6.7 7.4 13.1 1.7 9.4 4.3 2.9 2 0 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV HOIP-UBA PF16678.5 CEH19602.1 - 0.027 14.5 0.1 0.027 14.5 0.1 1.1 1 0 0 1 1 1 0 HOIP UBA domain pair Mit_KHE1 PF10173.9 CEH19604.1 - 0.16 12.0 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related His_Phos_1 PF00300.22 CEH19605.1 - 2.5e-15 56.7 0.0 5.1e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MerR-DNA-bind PF09278.11 CEH19605.1 - 0.65 10.6 4.6 0.34 11.5 1.6 2.0 1 1 1 2 2 2 0 MerR, DNA binding Plexin_cytopl PF08337.12 CEH19606.1 - 0.044 12.5 0.5 0.073 11.7 0.5 1.3 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain HlyIII PF03006.20 CEH19607.1 - 4.1e-44 151.0 12.8 5.6e-44 150.5 12.8 1.2 1 0 0 1 1 1 1 Haemolysin-III related DUF1691 PF07950.11 CEH19607.1 - 0.022 15.5 0.7 0.048 14.4 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Na_H_Exchanger PF00999.21 CEH19609.1 - 1.1e-37 129.7 43.1 1e-20 73.9 18.3 2.3 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family PALP PF00291.25 CEH19610.1 - 6e-61 206.4 0.9 1.1e-39 136.6 0.1 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme CTP_transf_3 PF02348.19 CEH19610.1 - 0.049 13.6 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Titin_Z PF09042.11 CEH19610.1 - 0.57 10.2 5.3 0.18 11.8 1.6 2.0 2 0 0 2 2 2 0 Titin Z DUF3395 PF11875.8 CEH19611.1 - 4.8e-34 117.5 0.0 9.4e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CEH19611.1 - 2.7e-18 65.8 0.1 4.7e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain ABC_membrane PF00664.23 CEH19612.1 - 4e-60 203.8 20.1 1.7e-33 116.5 5.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEH19612.1 - 4.3e-51 173.0 0.1 1.8e-30 106.2 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEH19612.1 - 3.8e-08 33.0 4.6 0.0024 17.3 1.6 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEH19612.1 - 1.9e-07 31.6 1.9 0.0071 16.7 1.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 CEH19612.1 - 6.4e-07 29.5 0.2 0.02 15.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 CEH19612.1 - 1.4e-06 28.4 0.1 0.031 14.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEH19612.1 - 2.8e-06 27.0 0.4 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain cobW PF02492.19 CEH19612.1 - 1.4e-05 24.8 1.2 0.046 13.3 0.1 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CEH19612.1 - 2.1e-05 24.5 0.1 0.15 11.9 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CEH19612.1 - 7.4e-05 23.3 0.0 0.42 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 CEH19612.1 - 0.00011 21.4 0.1 0.0076 15.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.23 CEH19612.1 - 0.00013 22.1 0.6 0.11 12.6 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 CEH19612.1 - 0.00022 21.5 4.4 0.46 10.8 0.2 3.3 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CEH19612.1 - 0.00035 19.9 0.8 0.077 12.3 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin TrwB_AAD_bind PF10412.9 CEH19612.1 - 0.00094 18.2 1.6 0.026 13.4 0.2 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.14 CEH19612.1 - 0.0011 18.9 0.1 0.048 13.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 CEH19612.1 - 0.0012 18.6 10.2 0.063 13.0 0.1 3.7 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 CEH19612.1 - 0.0013 19.2 0.2 0.86 10.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CEH19612.1 - 0.0021 18.1 0.4 1.1 9.3 0.1 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CEH19612.1 - 0.0027 17.2 0.2 2.4 7.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region ATP_bind_1 PF03029.17 CEH19612.1 - 0.0041 16.9 0.6 1.3 8.7 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 CEH19612.1 - 0.0062 16.3 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CEH19612.1 - 0.0063 16.7 0.7 1.7 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CEH19612.1 - 0.007 15.7 0.2 1.9 7.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Roc PF08477.13 CEH19612.1 - 0.0077 16.4 0.2 3.1 8.0 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 CEH19612.1 - 0.016 15.3 0.3 0.2 11.7 0.0 2.5 3 0 0 3 3 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 CEH19612.1 - 0.017 15.3 0.4 2.8 8.2 0.1 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 CEH19612.1 - 0.021 14.7 2.5 4.2 7.3 0.2 2.6 2 0 0 2 2 2 0 NACHT domain Adeno_IVa2 PF02456.15 CEH19612.1 - 0.023 13.5 0.0 0.52 9.0 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein IstB_IS21 PF01695.17 CEH19612.1 - 0.054 13.2 0.1 7.7 6.2 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 CEH19612.1 - 0.057 13.8 2.7 11 6.4 0.2 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 CEH19612.1 - 0.074 12.6 2.0 1.7 8.1 0.0 2.7 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 CEH19612.1 - 0.074 12.0 0.9 0.5 9.3 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PIF1 PF05970.14 CEH19612.1 - 0.096 11.8 0.0 6.6 5.8 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase ATP-synt_ab PF00006.25 CEH19612.1 - 0.1 12.2 0.3 4.7 6.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 CEH19612.1 - 0.11 12.8 0.8 24 5.4 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_5 PF07728.14 CEH19612.1 - 0.12 12.4 0.9 47 4.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 CEH19612.1 - 0.14 12.3 0.0 0.69 10.0 0.0 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 CEH19612.1 - 0.19 11.4 0.0 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CEH19612.1 - 0.41 10.2 7.2 8 6.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 CEH19612.1 - 0.64 9.2 2.5 1.5 7.9 0.1 2.5 3 0 0 3 3 3 0 NB-ARC domain DEAD PF00270.29 CEH19612.1 - 3 7.6 5.5 16 5.2 2.6 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase AMP-binding PF00501.28 CEH19613.1 - 5.5e-196 651.2 0.0 1.2e-68 231.6 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 CEH19613.1 - 2e-135 452.0 0.0 1.4e-29 103.1 0.0 6.2 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.25 CEH19613.1 - 8.9e-26 90.0 11.3 4.7e-06 26.9 0.2 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CEH19613.1 - 4.1e-08 34.1 0.0 0.1 13.6 0.0 4.0 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 CEH19613.1 - 4e-05 23.5 2.3 0.42 10.3 0.1 4.4 4 0 0 4 4 4 2 Wax ester synthase-like Acyl-CoA acyltransferase domain zf-CCHC PF00098.23 CEH19614.1 - 3.3e-07 30.1 1.0 6.6e-07 29.1 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEH19614.1 - 0.00018 21.2 2.2 0.00035 20.3 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CEH19614.1 - 0.00025 21.2 0.1 0.00025 21.2 0.1 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_5 PF14787.6 CEH19614.1 - 0.00042 20.0 1.6 0.0012 18.5 1.6 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CEH19614.1 - 0.11 12.5 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Ceraceosorus_bombacis/GCA_900000165.1_Ceraceosorus_bombacis_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Ceraceosorus_bombacis/GCA_900000165.1_Ceraceosorus_bombacis_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Ceraceosorus_bombacis/GCA_900000165.1_Ceraceosorus_bombacis_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Ceraceosorus_bombacis/GCA_900000165.1_Ceraceosorus_bombacis_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 16:13:52 2019 # [ok]