# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- zf-C3HC4_3 PF13920.1 CEG19311.1 - 1.2 8.9 8.0 2 8.1 5.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Acetyltransf_1 PF00583.19 CEG19324.1 - 0.00095 19.1 0.1 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 CEG19324.1 - 0.0071 16.3 0.1 0.0095 15.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEG19324.1 - 0.031 14.0 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 FR47-like protein SinI PF08671.5 CEG19325.1 - 0.54 9.7 2.0 21 4.6 0.0 2.1 2 0 0 2 2 2 0 Anti-repressor SinI DUF3453 PF11935.3 CEG19327.1 - 0.098 12.0 0.6 0.11 11.8 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) DUF16 PF01519.11 CEG19327.1 - 0.39 10.9 3.1 0.53 10.5 2.1 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 SIMPL PF04402.9 CEG19334.1 - 0.011 15.6 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Rieske PF00355.21 CEG19335.1 - 0.016 14.7 0.1 0.025 14.1 0.0 1.3 1 1 0 1 1 1 0 Rieske [2Fe-2S] domain Clat_adaptor_s PF01217.15 CEG19336.1 - 3.8e-15 55.8 0.0 8.2e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain CDC37_N PF03234.9 CEG19340.1 - 5e-31 108.3 0.6 5.1e-31 108.3 0.4 1.0 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding TAF1D PF15333.1 CEG19340.1 - 0.079 12.7 0.1 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D PS_Dcarbxylase PF02666.10 CEG19341.1 - 6.9e-18 64.6 0.0 7.8e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF3074 PF11274.3 CEG19342.1 - 1.1e-05 25.1 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) PAH PF02671.16 CEG19347.1 - 0.034 13.7 0.0 0.09 12.4 0.0 1.7 1 1 0 1 1 1 0 Paired amphipathic helix repeat DUF3072 PF11272.3 CEG19348.1 - 0.039 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) CTP_transf_1 PF01148.15 CEG19352.1 - 1.9e-26 93.3 0.2 2.2e-26 93.0 0.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family OTU PF02338.14 CEG19353.1 - 0.033 14.7 0.1 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 OTU-like cysteine protease gpD PF02925.11 CEG19358.1 - 5.9e-92 304.8 1.7 6.8e-92 304.7 1.2 1.0 1 0 0 1 1 1 1 Bacteriophage scaffolding protein D DUF2560 PF10834.3 CEG19358.1 - 0.07 13.1 0.3 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) Microvir_H PF04687.7 CEG19359.1 - 3.5e-181 601.0 22.8 4.2e-181 600.8 15.8 1.0 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) MRP-S31 PF15433.1 CEG19359.1 - 0.29 10.5 12.6 0.4 10.0 8.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 rRNA_processing PF08524.6 CEG19359.1 - 0.48 10.1 11.2 13 5.5 9.0 2.0 1 1 1 2 2 2 0 rRNA processing Myb_DNA-bind_3 PF12776.2 CEG19359.1 - 0.94 10.1 6.3 2.7 8.6 0.5 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain ABC2_membrane_3 PF12698.2 CEG19359.1 - 8.6 5.2 8.8 14 4.6 6.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein RVT_1 PF00078.22 CEG19362.1 - 4.1e-08 32.8 0.2 2.9e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyl-CoA_dh_1 PF00441.19 CEG19367.1 - 8.2e-29 100.6 0.1 8.9e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 CEG19367.1 - 1.4e-07 31.8 0.0 1.5e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain EMP24_GP25L PF01105.19 CEG19368.1 - 1.5e-25 90.0 0.1 1.6e-25 89.8 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribosomal_L32e PF01655.13 CEG19375.1 - 0.00019 21.4 0.1 0.00029 20.8 0.0 1.5 1 1 1 2 2 2 1 Ribosomal protein L32 Oxidored_q1 PF00361.15 CEG19376.1 - 4.9e-27 94.8 14.2 4.9e-27 94.8 9.9 2.2 1 1 1 2 2 2 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Cytochrom_B_C PF00032.12 CEG19377.1 - 2e-11 43.9 1.1 3.4e-11 43.2 0.7 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD AP2 PF00847.15 CEG19377.1 - 0.04 14.0 0.5 0.07 13.2 0.1 1.6 2 0 0 2 2 2 0 AP2 domain Oxidored_q1 PF00361.15 CEG19378.1 - 2.3e-63 214.0 14.7 2.3e-63 214.0 10.2 3.5 3 1 1 4 4 4 1 NADH-Ubiquinone/plastoquinone (complex I), various chains NADH5_C PF06455.6 CEG19378.1 - 1.3e-10 40.9 22.9 1.9e-10 40.4 10.9 3.2 2 1 0 2 2 2 1 NADH dehydrogenase subunit 5 C-terminus Baculo_E56 PF04639.7 CEG19378.1 - 0.23 10.1 5.8 0.12 11.0 1.1 2.2 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope COX1 PF00115.15 CEG19379.1 - 1.1e-95 320.9 36.6 1.2e-95 320.8 25.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I E1-E2_ATPase PF00122.15 CEG19379.1 - 0.69 8.8 3.0 1.3 8.0 2.1 1.4 1 0 0 1 1 1 0 E1-E2 ATPase ATP-synt_A PF00119.15 CEG19380.1 - 3.6e-51 173.7 23.3 4.3e-51 173.4 16.2 1.1 1 0 0 1 1 1 1 ATP synthase A chain COX3 PF00510.13 CEG19381.1 - 1.2e-112 375.5 20.7 1.3e-112 375.4 14.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III GIY-YIG PF01541.19 CEG19382.1 - 1.3e-07 31.8 0.2 1.1e-06 28.9 0.0 2.3 2 0 0 2 2 2 1 GIY-YIG catalytic domain zf-CCHC_3 PF13917.1 CEH11663.1 - 7.9e-15 54.3 0.7 1.3e-14 53.6 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle MMR_HSR1 PF01926.18 CEH11670.1 - 1.8e-06 27.8 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Abhydrolase_6 PF12697.2 CEH11670.1 - 1.8e-06 27.9 0.0 2.7e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.3 CEH11670.1 - 4e-05 23.0 0.0 7.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 CEH11670.1 - 0.00039 20.0 0.0 0.00089 18.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) ABC_tran PF00005.22 CEH11670.1 - 0.0041 17.4 0.0 0.013 15.8 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Septin PF00735.13 CEH11670.1 - 0.012 14.7 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_29 PF13555.1 CEH11670.1 - 0.064 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF676 PF05057.9 CEH11670.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_22 PF13401.1 CEH11670.1 - 0.071 13.2 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CEH11670.1 - 0.073 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 CEH11670.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CEH11670.1 - 0.23 11.2 0.0 19 5.0 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Caerin_1 PF07440.7 CEH11671.1 - 0.0068 16.2 0.2 0.019 14.8 0.1 1.8 1 0 0 1 1 1 1 Caerin 1 protein PTPA PF03095.10 CEH11672.1 - 1.4e-83 280.5 0.0 1.9e-83 280.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MAT1 PF06391.8 CEH11673.1 - 2e-21 76.4 3.7 3.2e-21 75.8 2.6 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 EI24 PF07264.6 CEH11674.1 - 1.3e-25 90.1 11.9 1.9e-25 89.6 8.2 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF273 PF03314.9 CEH11674.1 - 0.18 11.1 0.1 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 PRA1 PF03208.14 CEH11674.1 - 3.7 6.8 9.9 0.87 8.9 1.9 2.2 2 0 0 2 2 2 0 PRA1 family protein JAB PF01398.16 CEH11675.1 - 2.2e-18 66.0 0.0 6.4e-18 64.5 0.0 1.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CEH11675.1 - 9.6e-11 41.7 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Cas_VVA1548 PF09652.5 CEH11675.1 - 0.11 12.4 0.2 0.92 9.5 0.0 2.4 3 0 0 3 3 3 0 Putative CRISPR-associated protein (Cas_VVA1548) Ribosomal_L19 PF01245.15 CEH11676.1 - 3.5e-24 84.7 0.7 3.5e-24 84.7 0.5 1.5 2 0 0 2 2 2 1 Ribosomal protein L19 APC_CDC26 PF10471.4 CEH11676.1 - 7.8 7.3 12.4 2 9.2 6.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Ribosomal_L6 PF00347.18 CEH11677.1 - 4.6e-23 81.5 0.7 1.1e-11 45.0 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 DUF4338 PF14236.1 CEH11677.1 - 0.062 11.9 0.0 0.075 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) polyprenyl_synt PF00348.12 CEH11678.1 - 3.1e-33 114.7 0.1 6.7e-25 87.4 0.0 3.4 1 1 2 3 3 3 3 Polyprenyl synthetase Methyltransf_23 PF13489.1 CEH11679.1 - 4.5e-07 29.7 0.0 8.1e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH11679.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH11679.1 - 0.00011 22.4 0.0 0.00039 20.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH11679.1 - 0.00016 22.0 0.2 0.0032 17.8 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH11679.1 - 0.00037 20.9 0.0 0.064 13.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH11679.1 - 0.00046 19.7 0.0 0.59 9.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CEH11679.1 - 0.0031 18.0 0.0 0.22 12.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 CEH11679.1 - 0.077 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.9 CEH11679.1 - 0.13 11.6 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain MKT1_C PF12246.3 CEH11682.1 - 0.16 10.9 0.0 3.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication DUF1900 PF08954.6 CEH11683.1 - 4.9e-46 155.6 0.0 1.3e-45 154.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CEH11683.1 - 9.7e-31 105.2 0.2 1.8e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CEH11683.1 - 1.4e-13 50.1 7.4 2.2e-07 30.4 0.2 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Frataxin_Cyay PF01491.11 CEH11684.1 - 3.3e-32 110.5 0.0 4.6e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Unstab_antitox PF09720.5 CEH11684.1 - 0.09 12.4 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Putative addiction module component Saccharop_dh PF03435.13 CEH11685.1 - 4.4e-23 81.9 0.0 5.7e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CEH11685.1 - 0.0016 18.4 0.1 0.0029 17.6 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CEH11685.1 - 0.0029 17.0 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CEH11685.1 - 0.036 14.1 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 CEH11685.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FGGY_C PF02782.11 CEH11686.1 - 1.9e-21 76.5 0.0 5e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CEH11686.1 - 4.6e-09 35.9 0.0 3.1e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain HSP70 PF00012.15 CEH11686.1 - 0.0056 14.6 0.0 0.0082 14.1 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein DUF1325 PF07039.6 CEH11689.1 - 9.2e-28 96.4 0.0 1.6e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.5 CEH11689.1 - 0.0097 15.5 0.2 0.016 14.7 0.2 1.3 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain TUDOR PF00567.19 CEH11689.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Tudor domain Period_C PF12114.3 CEH11689.1 - 3.8 7.0 10.7 9 5.8 7.4 1.6 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Pneumo_att_G PF05539.6 CEH11689.1 - 5 6.3 20.0 0.064 12.6 8.7 1.5 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G AA_permease_2 PF13520.1 CEH11690.1 - 1.8e-52 178.3 55.3 2.2e-52 178.0 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEH11690.1 - 1.5e-09 36.7 49.0 2.1e-09 36.2 34.0 1.2 1 0 0 1 1 1 1 Amino acid permease CoA_transf_3 PF02515.12 CEH11692.1 - 0.11 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 CoA-transferase family III IncA PF04156.9 CEH11692.1 - 0.14 11.7 0.3 0.24 11.0 0.2 1.4 1 1 0 1 1 1 0 IncA protein zf-CCCH_2 PF14608.1 CEH11693.1 - 2.2e-10 40.0 41.4 0.0015 18.4 1.1 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 CEH11693.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Myb_DNA-binding PF00249.26 CEH11694.1 - 3.3e-11 43.0 3.0 7.5e-05 22.7 0.1 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH11694.1 - 1e-09 38.3 1.7 7.9e-06 25.8 0.0 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CEH11694.1 - 0.00027 21.0 1.8 0.00027 21.0 1.2 3.3 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain TAF4 PF05236.9 CEH11694.1 - 4.4 6.5 32.4 1.5 7.9 0.5 2.8 3 0 0 3 3 3 0 Transcription initiation factor TFIID component TAF4 family PseudoU_synth_2 PF00849.17 CEH11695.1 - 4.1e-23 82.0 0.0 9.8e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 RNA pseudouridylate synthase UPF0020 PF01170.13 CEH11695.1 - 2.6e-14 53.1 0.0 6.2e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CEH11695.1 - 6.8e-14 51.9 0.2 4.4e-13 49.2 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.3 CEH11695.1 - 0.034 13.1 0.0 1.1 8.2 0.0 2.4 1 1 1 2 2 2 0 RRNA methyltransferase AviRa K_oxygenase PF13434.1 CEH11695.1 - 0.076 11.9 0.0 0.19 10.5 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) WD40 PF00400.27 CEH11696.1 - 1.4e-10 40.6 18.9 0.0016 18.2 0.0 6.5 5 2 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.17 CEH11696.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain TauD PF02668.11 CEH11697.1 - 7.3e-29 101.2 0.0 9.3e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Dict-STAT-coil PF09267.5 CEH11697.1 - 0.083 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil F-box-like PF12937.2 CEH11698.1 - 0.0005 19.7 0.5 0.0017 18.0 0.0 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 CEH11698.1 - 0.011 15.4 0.0 0.03 13.9 0.0 1.8 1 0 0 1 1 1 0 F-box domain PRANC PF09372.5 CEH11698.1 - 0.062 13.2 0.1 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 PRANC domain GMC_oxred_C PF05199.8 CEH11699.1 - 2.6e-34 118.5 0.0 4.1e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CEH11699.1 - 3.4e-34 118.3 0.1 3.8e-24 85.3 0.0 2.2 1 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 CEH11699.1 - 1.3e-07 30.8 0.5 3.1e-06 26.3 0.4 2.2 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 CEH11699.1 - 8.5e-05 21.6 0.1 0.00014 20.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 CEH11699.1 - 0.00021 21.2 0.1 0.00054 19.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEH11699.1 - 0.00028 19.9 0.1 0.00077 18.4 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CEH11699.1 - 0.00031 20.8 0.0 0.012 15.6 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CEH11699.1 - 0.0039 16.3 0.0 0.0082 15.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 CEH11699.1 - 0.0075 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEH11699.1 - 0.043 12.2 0.1 0.063 11.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein CwfJ_C_1 PF04677.10 CEH11700.1 - 1.8e-26 92.1 0.0 2.8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CEH11700.1 - 1.2e-12 48.1 0.1 3.7e-12 46.5 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 FMO-like PF00743.14 CEH11701.1 - 5.3e-37 127.2 0.0 2.1e-15 55.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CEH11701.1 - 3.2e-11 43.6 0.0 1.5e-10 41.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEH11701.1 - 2.5e-08 33.8 0.3 3.3e-07 30.2 0.2 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CEH11701.1 - 3.6e-08 33.5 0.0 0.0001 22.2 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH11701.1 - 1.4e-05 24.9 0.1 7.5e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CEH11701.1 - 0.011 16.1 0.0 7.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CEH11701.1 - 0.018 14.1 0.1 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.1 CEH11701.1 - 0.038 12.9 0.0 18 4.1 0.0 3.2 4 0 0 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) TPR_8 PF13181.1 CEH11701.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Shikimate_DH PF01488.15 CEH11701.1 - 0.095 12.7 0.2 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L11 PF00298.14 CEH11702.1 - 1.3e-24 86.1 0.2 2.5e-24 85.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 CEH11702.1 - 2.9e-24 84.2 0.3 5.2e-24 83.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Reprolysin_5 PF13688.1 CEH11703.1 - 4.4e-40 137.6 8.9 4.4e-40 137.6 6.2 3.3 4 1 1 5 5 5 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 CEH11703.1 - 2.1e-37 128.6 1.1 4.8e-37 127.5 0.8 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CEH11703.1 - 9.6e-37 126.6 3.8 2.8e-36 125.2 2.6 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CEH11703.1 - 1.1e-20 74.3 0.5 1.1e-20 74.3 0.4 2.8 3 0 0 3 3 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CEH11703.1 - 4.3e-13 49.2 26.3 4.3e-13 49.2 18.2 4.3 2 1 2 4 4 2 1 Disintegrin Pep_M12B_propep PF01562.14 CEH11703.1 - 1.5e-08 34.4 0.1 3.9e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.14 CEH11703.1 - 3e-07 30.2 8.3 3.5e-05 23.5 5.7 3.2 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M43 PF05572.8 CEH11703.1 - 0.015 14.9 0.1 0.04 13.5 0.1 1.7 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.19 CEH11703.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M64 PF09471.5 CEH11703.1 - 0.18 11.4 0.1 0.31 10.6 0.1 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 HemY_N PF07219.8 CEH11703.1 - 0.22 11.0 0.5 0.48 10.0 0.3 1.5 1 0 0 1 1 1 0 HemY protein N-terminus DUF2937 PF11157.3 CEH11703.1 - 0.3 10.3 0.5 14 4.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF2420 PF10336.4 CEH11705.1 - 1.1e-16 60.4 0.0 2.2e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Ribosomal_L28 PF00830.14 CEH11706.1 - 3.8e-18 65.0 0.9 6.7e-18 64.2 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L28 family HMG_box PF00505.14 CEH11707.1 - 5.8e-13 48.9 0.2 1.2e-12 47.9 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEH11707.1 - 0.0017 18.6 0.0 0.005 17.1 0.0 1.8 1 0 0 1 1 1 1 HMG-box domain DUF3846 PF12957.2 CEH11708.1 - 0.058 13.1 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) ASFV_J13L PF05568.6 CEH11708.1 - 4.9 6.6 6.5 5.8 6.4 4.5 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein MIF4G PF02854.14 CEH11709.1 - 9.3e-55 185.2 0.2 1.4e-54 184.6 0.1 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CEH11709.1 - 3.3e-23 81.3 0.1 9.1e-23 79.9 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 CEH11709.1 - 4e-11 42.6 0.3 2e-10 40.3 0.1 2.1 2 0 0 2 2 2 1 MA3 domain Bromodomain PF00439.20 CEH11711.1 - 1.5e-21 76.0 0.1 2.6e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 CEH11711.1 - 1.1e-08 34.7 0.1 3.1e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated Lactamase_B_2 PF12706.2 CEH11712.1 - 1.2e-28 99.9 0.2 2.3e-28 99.0 0.1 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CEH11712.1 - 1.6e-05 24.6 0.8 0.0003 20.5 0.3 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Methyltransf_11 PF08241.7 CEH11713.1 - 4.6e-15 55.8 0.0 1.3e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH11713.1 - 1.6e-07 31.6 0.0 6.7e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH11713.1 - 1.7e-06 28.6 0.0 6.8e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH11713.1 - 3.8e-06 26.7 0.0 1e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH11713.1 - 1.4e-05 25.5 0.0 3.3e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 CEH11713.1 - 0.0076 15.0 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.1 CEH11713.1 - 0.013 15.1 0.0 0.044 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Pyridox_oxidase PF01243.15 CEH11714.1 - 0.00037 20.4 0.0 0.23 11.5 0.0 2.7 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase RabGAP-TBC PF00566.13 CEH11715.1 - 1.6e-51 174.8 0.0 2.2e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sugar_tr PF00083.19 CEH11717.1 - 5.7e-106 354.7 17.2 8.2e-106 354.2 11.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH11717.1 - 6.3e-24 84.3 15.8 6.3e-24 84.3 11.0 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CEH11717.1 - 6.7e-08 31.3 18.1 0.00027 19.4 0.8 3.3 3 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 CEH11717.1 - 1.9e-05 23.0 1.0 1.9e-05 23.0 0.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 CEH11717.1 - 0.0002 20.1 1.2 0.00037 19.3 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 CEH11717.1 - 0.0011 17.1 0.2 0.0011 17.1 0.1 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.2 CEH11717.1 - 0.11 12.3 0.0 0.11 12.3 0.0 3.5 4 0 0 4 4 4 0 MFS_1 like family EcKinase PF02958.15 CEH11719.1 - 1e-15 57.7 0.0 2.3e-14 53.2 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase RINGv PF12906.2 CEH11720.1 - 2.1e-16 59.6 10.6 4.2e-16 58.6 7.3 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CEH11720.1 - 4.5 7.1 15.0 0.32 10.8 6.8 1.9 2 0 0 2 2 2 0 Ring finger domain Pantoate_transf PF02548.10 CEH11721.1 - 8.3e-83 277.4 0.4 5.3e-78 261.7 0.1 2.2 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 CEH11721.1 - 0.009 15.2 0.0 0.027 13.6 0.0 1.7 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase Cytochrom_C1 PF02167.10 CEH11722.1 - 6.7e-83 277.6 0.0 9.5e-83 277.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CEH11722.1 - 0.00098 19.2 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CEH11722.1 - 0.054 14.3 0.1 0.16 12.7 0.1 2.0 2 1 0 2 2 2 0 Cytochrome c FAD_binding_2 PF00890.19 CEH11723.1 - 4.1e-123 411.3 2.7 5.3e-123 410.9 1.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CEH11723.1 - 1.8e-45 153.9 3.1 2.7e-45 153.3 2.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 CEH11723.1 - 2.4e-06 26.7 0.5 0.0044 16.1 0.1 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 CEH11723.1 - 0.00057 18.8 1.0 0.13 11.0 1.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 CEH11723.1 - 0.0021 17.0 0.1 0.0084 15.0 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CEH11723.1 - 0.011 15.6 4.3 0.056 13.3 0.1 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEH11723.1 - 0.056 12.4 0.3 0.09 11.8 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CEH11723.1 - 1.2 7.5 3.4 1.2 7.5 0.5 2.3 3 0 0 3 3 3 0 HI0933-like protein CorA PF01544.13 CEH11724.1 - 0.042 12.8 0.1 0.079 11.9 0.0 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3991 PF13154.1 CEH11724.1 - 0.053 13.7 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) RNA_polI_A34 PF08208.6 CEH11724.1 - 8.1 6.0 18.0 0.56 9.8 7.9 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Topoisom_I_N PF02919.10 CEH11727.1 - 6.1e-77 257.7 1.1 6.1e-77 257.7 0.8 2.5 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CEH11727.1 - 6.2e-59 198.9 1.7 1.8e-58 197.4 1.2 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CEH11727.1 - 7.6e-16 57.5 0.2 4e-13 48.8 0.0 2.8 2 0 0 2 2 2 2 C-terminal topoisomerase domain ACC_central PF08326.7 CEH11728.1 - 2.2e-183 611.1 0.0 3e-183 610.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CEH11728.1 - 9.7e-143 476.0 0.0 3.3e-142 474.3 0.0 1.8 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CEH11728.1 - 3e-53 180.2 0.0 5.5e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CEH11728.1 - 2.4e-23 82.3 0.1 1.1e-22 80.2 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CEH11728.1 - 5.3e-21 74.6 0.0 7e-19 67.7 0.0 3.6 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CEH11728.1 - 4e-13 48.7 0.0 8.6e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CEH11728.1 - 1e-11 44.9 0.0 2.8e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 CEH11728.1 - 0.00034 20.0 0.0 0.00086 18.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CEH11728.1 - 0.0032 17.1 0.0 0.011 15.3 0.0 2.0 1 0 0 1 1 1 1 Biotin-lipoyl like RimK PF08443.6 CEH11728.1 - 0.0066 15.9 0.0 0.053 12.9 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 CEH11728.1 - 0.016 14.5 0.0 0.044 13.1 0.0 1.7 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CEH11728.1 - 0.082 12.7 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain ABA_GPCR PF12430.3 CEH11730.1 - 8.9e-41 139.1 0.2 1.5e-40 138.4 0.2 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CEH11730.1 - 8.6e-11 41.7 0.0 4.1e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) DUF106 PF01956.11 CEH11731.1 - 1.8e-55 187.0 0.2 2.3e-55 186.6 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 DUF2617 PF10936.3 CEH11732.1 - 0.068 12.7 0.0 0.068 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF2617 RdRP PF05183.7 CEH11733.1 - 6.1e-99 332.2 0.0 9.4e-99 331.6 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase CRAL_TRIO PF00650.15 CEH11734.1 - 4e-30 104.4 0.0 5.9e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEH11734.1 - 5.6e-12 45.6 0.1 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CEH11734.1 - 1.3e-11 44.5 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Flavin_Reduct PF01613.13 CEH11735.1 - 5.4e-18 65.3 7.1 2.4e-17 63.2 4.9 2.1 1 1 0 1 1 1 1 Flavin reductase like domain PTPA PF03095.10 CEH11736.1 - 1e-111 372.9 0.0 1.3e-111 372.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Snf7 PF03357.16 CEH11737.1 - 1.6e-42 144.7 12.7 2.1e-42 144.4 8.8 1.1 1 0 0 1 1 1 1 Snf7 Peptidase_C11 PF03415.9 CEH11737.1 - 0.0013 17.7 0.9 0.0017 17.4 0.6 1.0 1 0 0 1 1 1 1 Clostripain family Prefoldin_2 PF01920.15 CEH11737.1 - 0.076 12.7 5.2 0.44 10.3 0.0 2.9 2 1 0 2 2 2 0 Prefoldin subunit Cas_Csx8 PF09657.5 CEH11737.1 - 0.11 11.1 2.4 2.1 7.0 0.1 2.0 1 1 1 2 2 2 0 CRISPR-associated protein Csx8 (Cas_Csx8) Laminin_II PF06009.7 CEH11737.1 - 0.19 11.4 6.0 1.3 8.8 1.2 2.2 1 1 0 2 2 2 0 Laminin Domain II DUF848 PF05852.6 CEH11737.1 - 0.48 10.2 4.8 0.38 10.5 1.7 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) zf-C4H2 PF10146.4 CEH11737.1 - 0.48 10.3 4.1 0.53 10.2 2.5 1.5 1 1 1 2 2 2 0 Zinc finger-containing protein TMF_DNA_bd PF12329.3 CEH11737.1 - 0.59 9.9 6.1 4.8 7.0 0.5 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 CEH11737.1 - 0.85 9.9 3.9 6.4 7.0 0.1 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 CEH11737.1 - 1.1 8.8 7.8 0.3 10.7 0.1 3.1 3 1 1 4 4 4 0 Prefoldin subunit YlqD PF11068.3 CEH11737.1 - 7.6 6.5 8.6 1.7 8.6 2.3 2.1 1 1 1 2 2 2 0 YlqD protein zf-C2H2 PF00096.21 CEH11739.1 - 3.3e-07 30.2 15.5 0.0011 19.2 3.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEH11739.1 - 0.0018 18.4 1.4 0.0018 18.4 1.0 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEH11739.1 - 0.046 14.0 14.8 0.39 11.1 3.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3587 PF12132.3 CEH11740.1 - 0.14 11.3 4.3 0.18 10.9 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) CENP-O PF09496.5 CEH11741.1 - 3.4e-14 52.8 0.0 8.4e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component GMC_oxred_N PF00732.14 CEH11743.1 - 3.9e-60 203.5 0.1 5.1e-60 203.1 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CEH11743.1 - 2.3e-32 112.2 0.1 5.8e-32 110.9 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CEH11743.1 - 0.00058 18.8 0.2 0.0014 17.6 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CEH11743.1 - 0.0072 15.2 1.3 0.021 13.7 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HHH PF00633.18 CEH11743.1 - 0.031 13.9 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif NAD_binding_8 PF13450.1 CEH11743.1 - 0.035 14.1 0.1 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Alpha-amylase_C PF02806.13 CEH11744.1 - 2e-23 82.3 0.1 9.6e-23 80.1 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CEH11744.1 - 1.2e-18 67.6 0.0 2.9e-13 49.8 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 CEH11744.1 - 5.2e-15 55.2 0.0 1.1e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) APG6 PF04111.7 CEH11745.1 - 1.6e-101 339.5 0.1 1.9e-101 339.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 CEH11745.1 - 0.54 8.0 6.5 0.69 7.6 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ARPC4 PF05856.7 CEH11746.1 - 1.1e-74 249.5 2.7 1.2e-74 249.3 1.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF3677 PF12432.3 CEH11746.1 - 0.12 12.8 0.2 14 6.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) Glyco_hydro_31 PF01055.21 CEH11747.1 - 2.1e-132 442.1 1.4 3e-132 441.5 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CEH11747.1 - 7.5e-17 60.9 0.1 3.5e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like KAR9 PF08580.5 CEH11748.1 - 0.00019 19.8 24.8 0.0038 15.5 16.5 3.2 1 1 1 2 2 2 1 Yeast cortical protein KAR9 GAS2 PF02187.12 CEH11748.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain DUF2422 PF10337.4 CEH11748.1 - 0.39 9.4 0.4 0.52 9.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Zw10 PF06248.8 CEH11748.1 - 0.46 8.5 0.2 0.66 8.0 0.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 IFT57 PF10498.4 CEH11748.1 - 0.86 8.2 3.0 8.3 5.0 0.4 2.1 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 Exo_endo_phos PF03372.18 CEH11749.1 - 1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ycf1 PF05758.7 CEH11749.1 - 1 7.0 3.5 1.4 6.4 2.4 1.1 1 0 0 1 1 1 0 Ycf1 Vma12 PF11712.3 CEH11751.1 - 3e-23 82.1 0.1 4.3e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Dppa2_A PF14049.1 CEH11751.1 - 0.43 10.4 4.2 0.25 11.1 1.0 2.1 2 1 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates DUF1690 PF07956.6 CEH11753.1 - 9.9e-15 54.7 9.2 9.9e-15 54.7 6.4 1.4 2 0 0 2 2 2 1 Protein of Unknown function (DUF1690) FliG_M PF14841.1 CEH11753.1 - 0.038 13.9 1.2 0.062 13.3 0.3 1.7 2 0 0 2 2 2 0 FliG middle domain CHCH PF06747.8 CEH11753.1 - 0.038 13.9 0.4 0.061 13.2 0.3 1.3 1 0 0 1 1 1 0 CHCH domain PerC PF06069.6 CEH11753.1 - 0.16 12.0 2.6 0.25 11.4 1.1 1.7 1 1 0 1 1 1 0 PerC transcriptional activator FlaC_arch PF05377.6 CEH11753.1 - 0.6 10.0 3.0 22 5.0 0.1 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 CEH11753.1 - 1.9 7.3 14.7 2.7 6.8 10.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cauli_DNA-bind PF03310.8 CEH11753.1 - 2.2 8.1 6.2 4.2 7.2 3.4 2.2 2 1 0 2 2 2 0 Caulimovirus DNA-binding protein Hex_IIIa PF02455.11 CEH11753.1 - 7 5.2 9.2 7.9 5.0 6.4 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF4140 PF13600.1 CEH11753.1 - 8.3 6.9 13.5 2.6 8.5 2.9 2.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) adh_short PF00106.20 CEH11754.1 - 6e-23 81.5 0.1 9.9e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH11754.1 - 6.9e-10 39.1 0.1 9.8e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CEH11754.1 - 6.1e-05 23.1 0.2 0.00011 22.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CEH11754.1 - 0.00016 21.4 0.1 0.00025 20.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CEH11754.1 - 0.027 13.3 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 CEH11754.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CEH11754.1 - 0.09 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CEH11754.1 - 0.098 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA_bind PF01588.15 CEH11755.1 - 9.9e-28 95.8 0.0 1.7e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.1 CEH11755.1 - 0.00012 21.9 0.1 0.00031 20.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEH11755.1 - 0.00069 20.0 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.22 CEH11756.1 - 2.9e-34 118.3 0.1 9.6e-34 116.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 CEH11756.1 - 3.4e-24 85.7 10.5 5.6e-24 84.9 7.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CEH11756.1 - 7.2e-06 26.1 0.0 0.0031 17.5 0.0 2.2 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CEH11756.1 - 8.7e-05 21.8 0.0 0.0033 16.7 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CEH11756.1 - 9.4e-05 22.4 1.3 0.00032 20.7 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CEH11756.1 - 0.0018 18.4 0.6 0.016 15.3 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CEH11756.1 - 0.0035 16.8 0.1 0.022 14.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 CEH11756.1 - 0.0057 15.8 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 COesterase PF00135.23 CEH11757.1 - 3.2e-89 300.0 0.0 5.9e-89 299.1 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CEH11757.1 - 4.1e-08 33.0 0.1 2.4e-07 30.5 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEH11757.1 - 0.014 14.5 0.2 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PQ-loop PF04193.9 CEH11759.1 - 1.2e-21 75.9 6.6 7.2e-16 57.4 0.2 2.7 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.13 CEH11759.1 - 0.038 14.4 0.1 0.038 14.4 0.0 2.4 2 2 0 2 2 2 0 ER lumen protein retaining receptor MFS_1 PF07690.11 CEH11760.1 - 3e-37 128.1 50.4 3e-37 128.1 34.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH11760.1 - 3.9e-12 45.4 0.5 3.9e-12 45.4 0.4 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter Bax1-I PF01027.15 CEH11761.1 - 1.5e-28 99.8 12.7 2.1e-28 99.3 8.8 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Prenyltrans PF00432.16 CEH11762.1 - 4e-48 160.6 4.0 2.9e-10 39.5 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CEH11762.1 - 5.3e-29 100.9 0.0 8.4e-11 42.2 0.0 3.8 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CEH11762.1 - 0.00033 20.6 0.0 0.096 12.7 0.0 2.9 1 1 2 3 3 3 3 Prenyltransferase-like tRNA-synt_2 PF00152.15 CEH11763.1 - 5.4e-71 239.0 0.0 7.7e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CEH11763.1 - 6.3e-13 48.3 0.0 1.4e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ish1 PF10281.4 CEH11763.1 - 0.087 12.9 0.2 0.67 10.0 0.1 2.5 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein TPP1 PF10341.4 CEH11763.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD An_peroxidase PF03098.10 CEH11765.1 - 7.4e-79 265.5 0.0 1e-76 258.4 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 CEH11765.1 - 7.9e-12 44.4 0.0 1.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 HAUS6_N PF14661.1 CEH11766.1 - 1.4 8.1 6.7 1.8 7.8 4.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2235 PF09994.4 CEH11767.1 - 2.9e-72 243.3 0.0 5.3e-72 242.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.6 CEH11767.1 - 0.0042 16.8 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Spo12 PF05032.7 CEH11768.1 - 1.3e-09 37.4 4.3 2.3e-09 36.7 3.0 1.4 1 0 0 1 1 1 1 Spo12 family Methyltransf_18 PF12847.2 CEH11769.1 - 2e-06 28.3 0.1 6.4e-06 26.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEH11769.1 - 5.7e-06 25.8 0.0 1.5e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 CEH11769.1 - 0.00016 20.9 0.0 0.00026 20.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CEH11769.1 - 0.0015 18.5 1.0 0.0093 15.9 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH11769.1 - 0.0019 17.9 0.0 0.011 15.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH11769.1 - 0.0034 16.9 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CEH11769.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB FmrO PF07091.6 CEH11769.1 - 0.18 10.8 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Fungal_trans PF04082.13 CEH11770.1 - 1.3e-16 60.2 0.0 2.5e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH11770.1 - 2.1e-07 30.7 11.6 3.6e-07 29.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.1 CEH11771.1 - 5e-15 56.1 0.0 1.7e-14 54.4 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEH11771.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like RCC1 PF00415.13 CEH11772.1 - 2.4e-30 104.4 11.6 1.5e-08 34.7 0.0 6.9 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CEH11772.1 - 4.1e-19 67.6 17.1 3.9e-06 26.3 1.2 5.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 CEH11772.1 - 8.2e-08 31.8 8.3 1.8e-07 30.7 5.7 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 CEH11772.1 - 0.019 14.9 2.1 0.059 13.3 1.4 1.9 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 CEH11772.1 - 0.069 12.8 1.0 0.24 11.1 0.7 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Polysacc_deac_1 PF01522.16 CEH11774.1 - 1.4e-28 99.0 0.0 2.7e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase PIN_2 PF10130.4 CEH11774.1 - 0.12 12.4 0.6 0.25 11.3 0.4 1.4 1 0 0 1 1 1 0 PIN domain Globin PF00042.17 CEH11774.1 - 0.17 12.2 0.0 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Globin HSP70 PF00012.15 CEH11775.1 - 1.4e-60 204.9 3.0 2.8e-58 197.2 0.1 2.9 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CEH11775.1 - 0.08 11.5 0.3 0.17 10.4 0.2 1.5 1 0 0 1 1 1 0 MreB/Mbl protein G-alpha PF00503.15 CEH11777.1 - 4.3e-128 427.3 0.3 5.1e-128 427.0 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEH11777.1 - 9.6e-16 57.5 0.3 3.5e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEH11777.1 - 0.00015 20.9 0.0 0.51 9.4 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CEH11777.1 - 0.0029 18.0 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 CEH11777.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_16 PF10294.4 CEH11778.1 - 6.6e-12 45.2 0.0 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CEH11778.1 - 0.00021 21.8 0.0 0.00057 20.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH11778.1 - 0.0016 18.4 2.9 0.0042 17.0 2.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH11778.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 CEH11778.1 - 0.037 13.1 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RhoGEF PF00621.15 CEH11779.1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 RhoGEF domain RhoGEF PF00621.15 CEH11780.1 - 4.4e-28 98.3 0.2 1.1e-27 97.1 0.0 1.6 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 CEH11780.1 - 4.8e-10 39.3 0.0 8.2e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 BAR domain DUF2015 PF09435.5 CEH11781.1 - 4.7e-27 94.3 0.0 5.3e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Amnionless PF14828.1 CEH11781.1 - 0.027 12.9 0.0 0.032 12.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless Mod_r PF07200.8 CEH11782.1 - 2.4e-18 66.4 10.5 9.2e-17 61.3 3.5 2.2 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein SCP-1 PF05483.7 CEH11782.1 - 0.0011 16.8 0.3 0.0012 16.7 0.2 1.0 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) NUDE_C PF04880.8 CEH11782.1 - 0.0036 17.6 1.0 0.0059 16.9 0.7 1.4 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region ATG16 PF08614.6 CEH11782.1 - 0.0049 16.7 4.9 0.032 14.0 2.1 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Rootletin PF15035.1 CEH11782.1 - 0.0059 16.6 5.5 0.0059 16.6 3.8 1.4 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF972 PF06156.8 CEH11782.1 - 0.051 13.9 1.2 0.1 12.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 CEH11782.1 - 0.6 9.1 4.8 0.74 8.7 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 CEH11782.1 - 1.9 6.7 8.7 2.2 6.6 6.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family polyprenyl_synt PF00348.12 CEH11784.1 - 3.4e-47 160.4 0.0 4.8e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase DUF663 PF04950.7 CEH11785.1 - 6.1e-80 268.3 0.0 8.6e-80 267.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) DUF676 PF05057.9 CEH11785.1 - 1.3e-27 96.5 0.0 1.9e-23 82.8 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) AARP2CN PF08142.7 CEH11785.1 - 2e-17 62.5 0.0 4.6e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Lipase_3 PF01764.20 CEH11785.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.20 CEH11786.1 - 2.4e-66 223.5 0.0 2.7e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH11786.1 - 4.8e-34 117.6 0.0 5.9e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH11786.1 - 0.00011 21.3 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEH11786.1 - 0.0098 14.9 0.0 0.025 13.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEH11786.1 - 0.018 14.7 0.2 0.064 12.9 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family FAD_binding_2 PF00890.19 CEH11786.1 - 0.042 12.6 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GtrA PF04138.9 CEH11786.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 GtrA-like protein eIF2A PF08662.6 CEH11787.1 - 2.1e-75 252.6 0.1 3.8e-74 248.5 0.0 2.8 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CEH11787.1 - 0.00022 20.9 0.3 6.7 6.7 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Proteasome_A_N PF10584.4 CEH11787.1 - 0.14 11.4 3.0 15 5.0 0.0 4.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature IKI3 PF04762.7 CEH11787.1 - 0.14 9.9 0.1 0.38 8.4 0.0 1.7 2 0 0 2 2 2 0 IKI3 family Y_phosphatase PF00102.22 CEH11788.1 - 4.9e-53 179.8 0.0 1.6e-25 89.8 0.0 3.1 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 CEH11788.1 - 8.3e-05 22.9 0.0 0.0013 19.0 0.0 2.8 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 CEH11788.1 - 0.0039 17.4 0.0 0.015 15.5 0.0 2.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 CEH11788.1 - 0.0061 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF3106 PF11304.3 CEH11788.1 - 0.007 16.7 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3106) PTPlike_phytase PF14566.1 CEH11788.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate AP_endonuc_2 PF01261.19 CEH11789.1 - 1.1e-13 50.9 0.0 4.1e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel Dynein_light PF01221.13 CEH11790.1 - 1.1e-37 127.8 0.8 1.5e-37 127.4 0.6 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 YcxB PF14317.1 CEH11790.1 - 0.16 11.2 0.3 2.9 7.1 0.1 2.2 2 0 0 2 2 2 0 YcxB-like protein DUF1218 PF06749.7 CEH11791.1 - 0.1 13.0 0.8 0.1 13.0 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Response_reg PF00072.19 CEH11792.1 - 1.2e-13 51.0 0.3 2.2e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain CPSase_L_D2 PF02786.12 CEH11793.1 - 3e-50 170.4 0.1 1.1e-26 93.4 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 CEH11793.1 - 9.9e-41 138.3 0.5 2.8e-25 88.4 0.0 2.7 2 1 1 3 3 3 2 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 CEH11793.1 - 6.5e-22 78.1 0.2 1.2e-16 60.9 0.1 2.9 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CEH11793.1 - 1e-17 63.8 0.0 1.4e-09 37.2 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_chain PF00289.17 CEH11793.1 - 4e-16 59.0 0.0 1e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp PF02222.17 CEH11793.1 - 2.7e-07 30.1 0.0 6.6e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CEH11793.1 - 0.00019 20.9 0.0 0.00042 19.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CEH11793.1 - 0.1 12.4 0.1 3.5 7.4 0.0 2.8 3 1 0 3 3 3 0 ATP-grasp domain Mito_carr PF00153.22 CEH11794.1 - 1.6e-65 216.8 3.4 5.9e-21 73.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein BTAD PF03704.12 CEH11794.1 - 0.035 14.4 0.3 0.055 13.7 0.2 1.2 1 0 0 1 1 1 0 Bacterial transcriptional activator domain UPF0029 PF01205.14 CEH11799.1 - 4.3e-09 36.0 0.0 1.8e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized protein family UPF0029 RabGAP-TBC PF00566.13 CEH11800.1 - 2.4e-31 108.8 0.0 3.6e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Zds_C PF08632.5 CEH11802.1 - 6.3e-20 70.3 1.3 1.1e-19 69.5 0.9 1.3 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Zn_clus PF00172.13 CEH11803.1 - 3.1e-09 36.5 9.3 5.7e-09 35.7 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CEH11803.1 - 4.6e-09 35.5 0.1 7.2e-09 34.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.15 CEH11804.1 - 5.3e-44 150.8 0.0 8.6e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CEH11804.1 - 2.6e-12 46.9 0.1 4.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Nuc_recep-AF1 PF11825.3 CEH11804.1 - 0.0085 16.0 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 BNR_2 PF13088.1 CEH11804.1 - 0.014 14.7 0.4 11 5.2 0.0 3.2 3 0 0 3 3 3 0 BNR repeat-like domain PSII_BNR PF14870.1 CEH11804.1 - 0.034 13.1 0.0 0.065 12.2 0.0 1.4 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Sugar_tr PF00083.19 CEH11805.1 - 6.1e-54 183.3 19.2 8.2e-54 182.8 13.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH11805.1 - 2.9e-19 68.9 24.7 4.7e-19 68.3 17.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_S11 PF00411.14 CEH11806.1 - 0.06 13.5 0.2 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S11 DUF4381 PF14316.1 CEH11807.1 - 0.0001 22.4 0.2 0.0001 22.4 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) CcmH PF03918.9 CEH11807.1 - 0.16 10.9 0.5 0.35 9.8 0.3 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein YajC PF02699.10 CEH11807.1 - 0.23 11.1 0.5 0.51 10.0 0.3 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit DUF2140 PF09911.4 CEH11807.1 - 0.37 9.9 0.6 0.69 9.0 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF1443 PF07280.6 CEH11807.1 - 0.53 9.9 2.1 0.79 9.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) DUF2500 PF10694.4 CEH11807.1 - 0.61 10.1 2.1 0.95 9.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) DUF4131 PF13567.1 CEH11807.1 - 0.92 8.8 3.1 2.6 7.4 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PgaD PF13994.1 CEH11807.1 - 1.3 8.4 4.3 0.38 10.2 0.5 1.9 2 0 0 2 2 2 0 PgaD-like protein Fungal_trans PF04082.13 CEH11808.1 - 2.1e-20 72.6 0.0 3.2e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH11808.1 - 8.3e-07 28.8 8.4 1.6e-06 27.9 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 CEH11809.1 - 2.3e-19 70.0 0.0 8.5e-17 61.7 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CEH11809.1 - 1.6e-07 31.5 0.1 0.00078 19.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CEH11809.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 CEH11809.1 - 0.00069 20.0 0.0 0.028 14.9 0.0 3.0 3 0 0 3 3 3 1 Miro-like protein DUF258 PF03193.11 CEH11809.1 - 0.0026 16.9 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 CEH11809.1 - 0.0033 16.5 0.0 0.33 9.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 CEH11809.1 - 0.024 14.9 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEH11809.1 - 0.028 14.0 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 CEH11809.1 - 0.046 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CEH11809.1 - 0.054 13.4 1.5 0.16 11.9 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.4 CEH11809.1 - 0.062 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Dynamin_N PF00350.18 CEH11809.1 - 0.11 12.3 0.1 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.1 CEH11809.1 - 0.14 12.2 0.0 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain zf-C2HC5 PF06221.8 CEH11810.1 - 7.6e-13 48.0 5.2 1.3e-12 47.2 3.6 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type PWI PF01480.12 CEH11810.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 PWI domain Ribosomal_60s PF00428.14 CEH11810.1 - 2.5 8.5 15.8 0.13 12.6 2.1 3.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein GtrA PF04138.9 CEH11811.1 - 0.027 14.4 0.9 0.027 14.4 0.6 1.8 2 0 0 2 2 2 0 GtrA-like protein Glyco_hydro_16 PF00722.16 CEH11812.1 - 8.4e-20 70.8 0.7 8.4e-20 70.8 0.5 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_35 PF01301.14 CEH11813.1 - 1.3e-61 208.7 0.0 1.9e-61 208.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 CEH11813.1 - 7.5e-37 125.9 3.8 5.4e-18 65.2 0.3 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 CEH11813.1 - 1.2e-26 93.1 1.2 1.2e-26 93.1 0.8 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 CEH11813.1 - 7.8e-14 50.8 0.9 2.3e-13 49.3 0.1 2.2 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 CEH11813.1 - 9.3e-05 21.7 0.0 0.00034 19.9 0.0 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) VHS PF00790.14 CEH11814.1 - 2.5e-25 88.7 0.1 5.7e-25 87.6 0.0 1.6 2 0 0 2 2 2 1 VHS domain SH3_9 PF14604.1 CEH11814.1 - 2.1e-16 59.2 0.1 4.6e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEH11814.1 - 6.6e-16 57.4 0.0 1.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEH11814.1 - 4.4e-12 45.2 0.0 1e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 CEH11814.1 - 3.3e-05 23.7 0.2 0.00011 22.1 0.1 1.9 1 0 0 1 1 1 1 GAT domain Hrs_helical PF12210.3 CEH11814.1 - 0.0016 18.6 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate UIM PF02809.15 CEH11814.1 - 6.4 6.6 7.6 0.19 11.4 0.4 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif Nsp1_C PF05064.8 CEH11815.1 - 6.1e-29 100.0 0.9 1.2e-28 99.0 0.2 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 CEH11815.1 - 1e-08 35.4 224.4 0.00021 21.4 21.4 6.5 1 1 5 6 6 6 4 Nucleoporin FG repeat region DUF4200 PF13863.1 CEH11815.1 - 0.089 12.7 3.2 0.19 11.6 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Laminin_II PF06009.7 CEH11815.1 - 0.12 12.1 0.8 0.63 9.7 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II Filament PF00038.16 CEH11815.1 - 0.21 10.9 3.3 0.48 9.8 2.3 1.4 1 1 0 1 1 1 0 Intermediate filament protein IncA PF04156.9 CEH11815.1 - 0.22 11.1 5.1 0.75 9.3 2.9 2.0 2 1 0 2 2 2 0 IncA protein Syntaxin PF00804.20 CEH11815.1 - 0.23 11.6 3.5 0.53 10.4 0.6 2.2 1 1 0 2 2 2 0 Syntaxin CENP-Q PF13094.1 CEH11815.1 - 0.25 11.3 3.6 1.4 8.9 0.0 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 CEH11815.1 - 0.32 10.8 2.5 0.52 10.1 0.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 CEH11815.1 - 0.35 10.2 3.5 0.83 9.0 0.6 2.5 3 0 0 3 3 3 0 Phage minor structural protein GP20 ERM PF00769.14 CEH11815.1 - 1 8.8 5.1 3.4 7.1 2.2 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family APG6 PF04111.7 CEH11815.1 - 1.5 7.8 4.3 2.2 7.2 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 NPV_P10 PF05531.7 CEH11815.1 - 1.7 8.9 4.3 19 5.5 0.0 2.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 CEH11815.1 - 8.6 6.2 10.2 17 5.2 2.3 2.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 tRNA-synt_1 PF00133.17 CEH11816.1 - 2.2e-145 485.0 0.0 3e-145 484.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CEH11816.1 - 1.1e-20 74.0 0.0 1.8e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CEH11816.1 - 2.9e-20 72.3 0.0 3.6e-12 45.6 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CEH11816.1 - 0.00087 18.6 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 CEH11816.1 - 0.0043 16.6 2.6 0.0078 15.8 1.8 1.4 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS DUF945 PF06097.6 CEH11816.1 - 0.26 10.0 0.0 0.39 9.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) V-ATPase_G PF03179.10 CEH11817.1 - 1.4e-32 112.1 16.9 1.6e-32 111.9 11.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 CEH11817.1 - 0.015 15.1 15.3 0.015 15.1 10.6 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) YdfA_immunity PF12127.3 CEH11817.1 - 0.023 13.6 4.8 0.022 13.6 2.9 1.3 1 1 0 1 1 1 0 SigmaW regulon antibacterial DUF2362 PF10154.4 CEH11817.1 - 0.034 12.8 3.7 0.041 12.5 2.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) RE_TaqI PF09573.5 CEH11817.1 - 0.11 11.6 3.1 0.14 11.3 2.1 1.1 1 0 0 1 1 1 0 TaqI restriction endonuclease DUF1675 PF07897.6 CEH11817.1 - 0.14 12.0 4.7 0.14 12.0 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Mod_r PF07200.8 CEH11817.1 - 0.62 9.9 10.6 1 9.2 7.4 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein RRF PF01765.14 CEH11817.1 - 0.9 8.9 8.6 1.3 8.4 6.0 1.3 1 0 0 1 1 1 0 Ribosome recycling factor IncA PF04156.9 CEH11817.1 - 1.1 8.8 11.2 0.46 10.0 4.7 1.9 1 1 1 2 2 2 0 IncA protein DUF1104 PF06518.6 CEH11817.1 - 1.3 9.1 9.4 2.5 8.2 6.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) ATP11 PF06644.6 CEH11817.1 - 1.6 8.1 8.5 1.9 7.9 5.9 1.1 1 0 0 1 1 1 0 ATP11 protein DUF3552 PF12072.3 CEH11817.1 - 2 7.6 18.7 4.2 6.5 13.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4407 PF14362.1 CEH11817.1 - 2.9 6.7 9.9 3.2 6.6 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MRP-S31 PF15433.1 CEH11817.1 - 3 7.1 10.1 3.5 6.9 7.0 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 APG6 PF04111.7 CEH11817.1 - 4.2 6.3 9.6 4.4 6.2 6.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Vfa1 PF08432.5 CEH11817.1 - 4.3 7.3 11.8 5.1 7.0 8.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NAPRTase PF04095.11 CEH11818.1 - 1.7e-51 174.8 0.0 6.6e-43 146.7 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Retrotrans_gag PF03732.12 CEH11818.1 - 0.026 14.5 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Pertussis_S2S3 PF02918.10 CEH11818.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain FMN_dh PF01070.13 CEH11819.1 - 7.6e-113 376.9 0.0 8.7e-113 376.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 CEH11819.1 - 1.5e-06 27.4 0.5 5e-06 25.6 0.2 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 CEH11819.1 - 0.0011 18.0 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 CEH11819.1 - 0.0057 15.7 0.2 0.51 9.3 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DSBA PF01323.15 CEH11820.1 - 2e-19 69.9 0.0 2.4e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Fungal_trans PF04082.13 CEH11822.1 - 2.3e-08 33.2 0.1 3.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH11822.1 - 7e-05 22.6 12.2 0.00013 21.7 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_luciferase PF00296.15 CEH11823.1 - 6.3e-62 209.4 0.8 8.3e-62 209.0 0.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DSS1_SEM1 PF05160.8 CEH11823.1 - 0.031 14.0 0.1 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 DSS1/SEM1 family PGM_PMM_I PF02878.11 CEH11824.1 - 1.1e-39 135.0 0.0 1.9e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CEH11824.1 - 3.3e-25 88.4 0.0 6.7e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CEH11824.1 - 3.5e-11 43.1 0.0 6.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CEH11824.1 - 1.4e-07 31.4 0.0 4.5e-06 26.5 0.0 2.6 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain FAA_hydrolase PF01557.13 CEH11825.1 - 6.7e-05 22.4 0.4 7e-05 22.3 0.2 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HHH PF00633.18 CEH11825.1 - 0.19 11.4 1.8 13 5.6 0.1 2.3 1 1 1 2 2 2 0 Helix-hairpin-helix motif FAA_hydrolase PF01557.13 CEH11826.1 - 6e-23 81.4 0.0 2.6e-12 46.6 0.0 2.0 2 0 0 2 2 2 2 Fumarylacetoacetate (FAA) hydrolase family Clathrin_bdg PF15045.1 CEH11826.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Pyridox_oxidase PF01243.15 CEH11827.1 - 1.1e-14 54.2 0.0 8.7e-14 51.3 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF374 PF04028.8 CEH11827.1 - 0.081 12.1 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Toxin_31 PF08119.6 CEH11828.1 - 0.94 9.0 4.6 1.6 8.3 0.3 2.1 2 0 0 2 2 2 0 Scorpion acidic alpha-KTx toxin family DUF3554 PF12074.3 CEH11829.1 - 1.7e-42 146.0 2.8 2.9e-41 142.0 0.0 3.9 6 0 0 6 6 6 1 Domain of unknown function (DUF3554) HEAT PF02985.17 CEH11829.1 - 3.7e-27 91.9 29.4 0.037 14.0 0.0 17.6 19 0 0 19 19 19 7 HEAT repeat HEAT_2 PF13646.1 CEH11829.1 - 5.4e-20 71.4 62.7 9.9e-08 32.1 0.1 14.7 11 5 5 16 16 16 5 HEAT repeats CLASP_N PF12348.3 CEH11829.1 - 1.5e-14 53.9 0.1 9.5e-07 28.3 0.0 6.7 4 1 0 5 5 5 1 CLASP N terminal HEAT_EZ PF13513.1 CEH11829.1 - 3.3e-12 46.4 48.5 0.0069 16.8 0.0 17.1 13 5 7 20 20 20 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CEH11829.1 - 5.9e-10 39.4 0.0 0.75 10.2 0.0 7.2 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region ParcG PF10274.4 CEH11829.1 - 7e-06 26.0 0.6 1.3 8.8 0.0 5.4 5 1 0 6 6 6 2 Parkin co-regulated protein Cnd1 PF12717.2 CEH11829.1 - 8.8e-06 25.6 0.0 7.7 6.3 0.0 7.2 4 1 4 8 8 8 1 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 CEH11829.1 - 0.0003 20.7 0.6 19 5.2 0.0 5.7 5 1 2 7 7 7 0 UME (NUC010) domain Adaptin_N PF01602.15 CEH11829.1 - 0.0008 17.8 0.1 28 2.8 0.0 6.4 8 0 0 8 8 8 0 Adaptin N terminal region DnaJ PF00226.26 CEH11830.1 - 1.2e-10 40.9 0.0 2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 CEH11831.1 - 3.2e-72 242.7 0.0 4.1e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH11831.1 - 9.3e-48 162.5 0.0 1.5e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CEH11831.1 - 6.7e-22 77.6 0.1 1.3e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 CEH11831.1 - 8.8e-05 21.6 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 CEH11831.1 - 0.017 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.18 CEH11831.1 - 0.031 13.9 0.1 0.35 10.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CEH11831.1 - 0.33 10.0 0.3 1.4 7.9 0.0 1.9 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MSP1_C PF07462.6 CEH11831.1 - 7.9 4.7 6.4 20 3.4 4.4 1.6 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Rad9 PF04139.8 CEH11833.1 - 1.2e-49 168.7 0.0 2.2e-49 167.8 0.0 1.4 2 0 0 2 2 2 1 Rad9 SNF5 PF04855.7 CEH11834.1 - 2.3e-59 200.8 0.2 3.2e-44 151.2 0.0 2.3 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 GATA PF00320.22 CEH11834.1 - 0.00052 19.2 1.5 0.0015 17.8 1.1 1.9 1 0 0 1 1 1 1 GATA zinc finger Aldo_ket_red PF00248.16 CEH11835.1 - 2.7e-32 111.7 0.0 3.7e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Mrr_cat PF04471.7 CEH11835.1 - 0.083 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease Proteasome PF00227.21 CEH11836.1 - 1.2e-52 177.9 0.1 1.5e-52 177.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEH11836.1 - 1.4e-14 53.0 0.0 2.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cellulase PF00150.13 CEH11837.1 - 1.2e-12 47.6 0.3 2e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 CEH11841.1 - 8.7e-64 215.1 0.0 9.7e-37 126.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH11841.1 - 2.1e-24 85.9 0.0 5.7e-21 74.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CEH11841.1 - 0.00092 18.3 0.1 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEH11841.1 - 0.0054 16.4 0.1 0.0054 16.4 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEH11841.1 - 0.039 12.9 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 CEH11841.1 - 0.05 12.9 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pyridox_oxase_2 PF12766.2 CEH11842.1 - 2.4e-19 69.4 0.0 3.8e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RPAP1_N PF08621.5 CEH11842.1 - 0.014 15.0 0.7 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 RPAP1-like, N-terminal Rep_fac_C PF08542.6 CEH11843.1 - 6.7e-19 67.6 0.0 1.2e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 CEH11843.1 - 4.5e-16 59.2 0.0 1.4e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CEH11843.1 - 1.1e-12 47.8 0.0 1.6e-11 44.1 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 CEH11843.1 - 8.2e-06 25.9 0.0 6.1e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH11843.1 - 4.5e-05 23.1 0.0 0.00012 21.7 0.0 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CEH11843.1 - 5.6e-05 22.8 0.0 0.00013 21.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CEH11843.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CEH11843.1 - 0.00014 21.5 0.0 0.00035 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 CEH11843.1 - 0.00016 21.3 0.0 0.00031 20.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CEH11843.1 - 0.00028 20.1 0.0 0.00058 19.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CEH11843.1 - 0.00084 19.3 0.0 0.014 15.4 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 CEH11843.1 - 0.0013 17.4 0.0 0.12 10.9 0.0 2.2 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 CEH11843.1 - 0.0018 17.7 0.0 0.0044 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CEH11843.1 - 0.0028 17.2 0.1 0.0064 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CEH11843.1 - 0.01 15.2 0.1 3.4 7.0 0.0 2.5 2 1 0 3 3 3 0 AAA-like domain RuvB_N PF05496.7 CEH11843.1 - 0.033 13.2 0.0 0.07 12.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 CEH11843.1 - 0.038 12.9 0.0 0.07 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 CEH11843.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.24 CEH11843.1 - 0.091 12.2 0.0 1.7 8.0 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.1 CEH11843.1 - 0.094 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 CEH11843.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNase_PH PF01138.16 CEH11844.1 - 1.2e-29 103.2 1.5 1.6e-21 77.0 0.0 2.6 1 1 1 2 2 2 2 3' exoribonuclease family, domain 1 MutL_C PF08676.6 CEH11845.1 - 5.9e-21 74.5 0.0 1.6e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 CEH11845.1 - 1.6e-17 63.0 0.0 3.8e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CEH11845.1 - 1e-12 47.8 0.0 2.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CEH11845.1 - 8.6e-11 41.5 0.1 2.4e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Anillin PF08174.6 CEH11845.1 - 0.0011 19.0 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 Cell division protein anillin TPPII_N PF12583.3 CEH11845.1 - 0.42 10.7 6.9 6.1 6.9 0.3 3.4 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal GIT_SHD PF08518.6 CEH11846.1 - 2.4e-25 87.5 9.6 3.6e-14 51.8 0.9 3.5 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT DUF812 PF05667.6 CEH11846.1 - 0.00067 18.2 17.3 0.00067 18.2 12.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF812) DUF3584 PF12128.3 CEH11846.1 - 0.025 11.9 24.1 0.004 14.5 13.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 CEH11846.1 - 0.026 14.2 20.4 1.1e+02 2.5 3.9 4.2 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein Fumble PF03630.9 CEH11846.1 - 0.11 11.3 2.3 0.19 10.5 1.6 1.3 1 0 0 1 1 1 0 Fumble Filament PF00038.16 CEH11846.1 - 0.63 9.4 34.9 0.15 11.5 11.2 3.0 2 1 1 3 3 3 0 Intermediate filament protein DUF244 PF03112.9 CEH11846.1 - 2.4 7.6 5.9 0.5 9.8 1.1 1.9 1 1 1 2 2 2 0 Uncharacterized protein family (ORF7) DUF SlyX PF04102.7 CEH11846.1 - 3.3 8.1 23.1 0.024 15.0 3.0 5.0 2 1 3 5 5 5 0 SlyX Mod_r PF07200.8 CEH11846.1 - 3.4 7.5 29.9 8.6 6.2 5.2 4.6 2 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein GPI2 PF06432.6 CEH11847.1 - 1.6e-34 119.5 0.0 2.2e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Zn_peptidase_2 PF04298.7 CEH11847.1 - 0.032 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Cellulase PF00150.13 CEH11848.1 - 1.9e-08 33.8 2.6 3.5e-08 32.9 1.8 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mucin PF01456.12 CEH11848.1 - 5.4 6.7 39.2 0.24 11.1 21.3 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Glyco_hydro_31 PF01055.21 CEH11850.1 - 2.1e-75 254.2 0.0 2.8e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CEH11850.1 - 1.8e-11 43.7 0.2 3.8e-11 42.6 0.2 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like PQ-loop PF04193.9 CEH11851.1 - 7.4e-27 92.6 3.8 3.3e-18 64.9 0.2 2.4 2 0 0 2 2 2 2 PQ loop repeat Abhydrolase_3 PF07859.8 CEH11852.1 - 1.1e-09 38.1 0.1 2.6e-08 33.7 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CEH11852.1 - 0.05 12.2 0.2 0.34 9.4 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) BAH PF01426.13 CEH11852.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 BAH domain DUF2985 PF11204.3 CEH11854.1 - 1.3e-14 53.7 0.6 4e-10 39.2 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2985) DUF2749 PF10907.3 CEH11854.1 - 0.088 12.6 2.0 2.6 7.9 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) bZIP_1 PF00170.16 CEH11856.1 - 1.7e-05 24.6 6.8 3.6e-05 23.6 4.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEH11856.1 - 0.0018 18.0 3.7 0.0037 17.0 2.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Chordopox_A30L PF06015.7 CEH11857.1 - 0.096 12.3 0.1 0.12 11.9 0.1 1.3 1 1 0 1 1 1 0 Chordopoxvirus A30L protein DUF4504 PF14953.1 CEH11858.1 - 5e-11 42.4 0.0 1e-06 28.3 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4504) Histone PF00125.19 CEH11859.1 - 4e-13 49.2 0.0 4.8e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CEH11859.1 - 9e-05 22.4 0.0 0.00015 21.7 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CEH11859.1 - 0.00021 21.1 0.1 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CEH11859.1 - 0.00026 21.1 0.0 0.00031 20.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CEH11859.1 - 0.0036 16.5 0.0 0.0038 16.5 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Histone PF00125.19 CEH11860.1 - 8.2e-30 102.7 0.8 1.4e-29 102.0 0.5 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CEH11860.1 - 2.4e-05 24.4 0.0 4.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CEH11860.1 - 0.00097 19.1 0.1 0.0022 18.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CEH11860.1 - 0.014 15.1 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated FMN_dh PF01070.13 CEH11863.1 - 1.6e-105 352.8 0.0 2.2e-105 352.4 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CEH11863.1 - 1.4e-19 69.6 0.0 3.3e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CEH11863.1 - 0.0003 19.8 0.0 0.00051 19.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CEH11863.1 - 0.0019 17.1 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 CEH11863.1 - 0.036 13.2 0.1 0.063 12.4 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Vfa1 PF08432.5 CEH11864.1 - 3.4 7.6 8.8 0.39 10.7 2.7 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 ELMO_CED12 PF04727.8 CEH11865.1 - 1.8e-28 99.1 0.0 2.7e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 CEH11865.1 - 9.3e-09 35.1 0.0 3.9e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Glyco_hydro_16 PF00722.16 CEH11866.1 - 3e-06 26.6 0.1 4.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SNO PF01174.14 CEH11867.1 - 2.2e-50 170.9 0.0 3.2e-37 127.9 0.0 3.0 2 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 CEH11867.1 - 9.7e-09 35.0 0.5 2.2e-08 33.8 0.1 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 CEH11867.1 - 0.0001 21.7 0.0 0.0073 15.7 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 CEH11867.1 - 0.0015 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 CEH11867.1 - 0.0049 16.6 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DUF4066 PF13278.1 CEH11867.1 - 0.028 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative amidotransferase DUF4154 PF13689.1 CEH11867.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) Racemase_4 PF13615.1 CEH11868.1 - 4.9e-06 26.7 0.2 1.3e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 Putative alanine racemase Bromodomain PF00439.20 CEH11869.1 - 0.0057 16.5 0.0 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 Bromodomain Hexapep PF00132.19 CEH11871.1 - 1.6e-11 43.1 21.1 3.8e-06 26.1 0.4 4.7 3 1 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CEH11871.1 - 7.9e-11 41.3 15.0 1.4e-05 24.5 1.1 4.1 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase AA_permease PF00324.16 CEH11872.1 - 5.4e-66 222.8 37.1 4.9e-55 186.7 14.9 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 CEH11872.1 - 8.2e-18 64.1 32.3 8.2e-18 64.1 22.4 1.6 1 1 1 2 2 2 1 Amino acid permease adh_short PF00106.20 CEH11872.1 - 8.9e-12 45.2 0.0 2.1e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH11872.1 - 6.8e-10 39.1 0.0 1.6e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH11872.1 - 9.3e-07 28.6 0.1 2.6e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 KR domain FAD_binding_4 PF01565.18 CEH11873.1 - 7e-15 54.7 0.0 1.3e-06 27.9 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain BBE PF08031.7 CEH11873.1 - 1.8e-07 30.9 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Far-17a_AIG1 PF04750.9 CEH11875.1 - 3.3e-36 124.3 1.7 3.8e-36 124.1 1.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Aminotran_1_2 PF00155.16 CEH11877.1 - 8.4e-59 199.3 0.0 1.2e-58 198.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Trp_syntA PF00290.15 CEH11878.1 - 1.1e-85 286.3 0.5 1.6e-85 285.8 0.1 1.5 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 CEH11878.1 - 4.4e-48 164.0 0.2 7.3e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 CEH11878.1 - 0.075 12.2 0.6 0.47 9.6 0.0 2.4 3 0 0 3 3 3 0 Histidine biosynthesis protein WD40 PF00400.27 CEH11879.1 - 0.0017 18.1 0.0 0.042 13.7 0.0 2.9 3 1 0 3 3 3 1 WD domain, G-beta repeat PMSR PF01625.16 CEH11880.1 - 7.6e-55 185.0 1.5 9.4e-55 184.7 1.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Cyclin PF08613.6 CEH11881.1 - 1.5e-36 126.0 0.0 2.4e-22 79.9 0.0 2.7 2 0 0 2 2 2 2 Cyclin GrpE PF01025.14 CEH11882.1 - 1.2e-44 151.7 0.0 1.9e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 GrpE IncA PF04156.9 CEH11882.1 - 0.059 12.9 3.8 0.14 11.7 2.5 1.5 1 1 0 1 1 1 0 IncA protein UCH PF00443.24 CEH11883.1 - 5.5e-78 261.7 0.0 1.1e-77 260.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEH11883.1 - 7.4e-21 74.8 0.0 1.2e-09 38.0 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CEH11883.1 - 1.5e-12 47.7 0.0 3.3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 DUSP domain CAP_N PF01213.14 CEH11883.1 - 1.1 8.5 8.4 0.032 13.5 1.0 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Velvet PF11754.3 CEH11884.1 - 1.5e-46 158.5 0.0 2.1e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Velvet PF11754.3 CEH11885.1 - 6.2e-24 84.7 0.0 9.6e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Velvet factor TPT PF03151.11 CEH11887.1 - 6.5e-21 74.5 9.1 7.9e-21 74.3 6.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.6 CEH11887.1 - 3.3e-05 22.9 4.3 3.8e-05 22.7 3.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CEH11887.1 - 0.00011 22.2 8.6 0.00015 21.7 5.9 1.2 1 0 0 1 1 1 1 EamA-like transporter family Nuc_sug_transp PF04142.10 CEH11887.1 - 0.00012 21.2 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF914 PF06027.7 CEH11887.1 - 0.0023 16.8 0.1 0.0029 16.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 CEH11887.1 - 0.15 12.2 5.2 0.19 11.9 3.6 1.1 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Multi_Drug_Res PF00893.14 CEH11887.1 - 0.26 11.7 3.8 0.41 11.1 2.6 1.4 1 0 0 1 1 1 0 Small Multidrug Resistance protein TPT PF03151.11 CEH11888.1 - 1.8e-06 27.7 1.6 2.5e-06 27.2 0.0 2.1 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 CEH11888.1 - 0.001 19.0 6.8 0.001 19.0 4.7 2.0 2 0 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 CEH11888.1 - 0.0036 16.2 2.2 0.0057 15.6 1.5 1.4 1 1 0 1 1 1 1 UAA transporter family Lectin_leg-like PF03388.8 CEH11889.1 - 3.3e-64 216.1 0.1 1.6e-33 115.7 0.1 2.1 1 1 1 2 2 2 2 Legume-like lectin family Lectin_legB PF00139.14 CEH11889.1 - 2.9e-07 30.1 0.0 0.00071 19.0 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain SR-25 PF10500.4 CEH11889.1 - 7.9 5.8 12.9 12 5.2 8.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_transf_22 PF03901.12 CEH11890.1 - 3e-47 161.5 13.5 3.8e-47 161.2 9.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Clat_adaptor_s PF01217.15 CEH11891.1 - 2.8e-55 185.9 2.9 3.1e-55 185.8 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-Di19 PF05605.7 CEH11892.1 - 0.089 12.9 0.2 0.089 12.9 0.1 4.9 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 CEH11892.1 - 1.5 9.2 10.8 33 5.0 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger double domain DUF776 PF05604.6 CEH11893.1 - 0.11 12.6 0.5 0.24 11.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF776) ADH_zinc_N_2 PF13602.1 CEH11894.1 - 1.5e-16 61.3 0.2 6.1e-16 59.4 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CEH11894.1 - 1.2e-11 44.2 1.4 3.1e-11 42.9 1.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH11894.1 - 0.007 16.1 0.1 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Gemini_AL1_M PF08283.6 CEH11894.1 - 0.092 12.5 0.1 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Geminivirus rep protein central domain zf-CCCH PF00642.19 CEH11895.1 - 0.00068 19.2 7.9 0.0019 17.8 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CEH11895.1 - 1.1 9.3 12.7 1.3 9.1 2.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type HEAT_EZ PF13513.1 CEH11896.1 - 2.9e-32 110.3 19.9 1.9e-11 44.0 0.0 11.2 9 3 3 12 12 12 7 HEAT-like repeat HEAT PF02985.17 CEH11896.1 - 1e-27 93.6 12.5 0.00017 21.3 0.0 9.4 10 0 0 10 10 8 5 HEAT repeat HEAT_2 PF13646.1 CEH11896.1 - 1e-25 89.7 0.6 1.1e-06 28.7 0.0 8.0 4 4 5 9 9 9 6 HEAT repeats IBN_N PF03810.14 CEH11896.1 - 8.3e-09 35.2 1.5 8.2e-08 32.0 0.1 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 CEH11896.1 - 1.2e-08 35.1 0.0 0.0023 18.2 0.0 4.1 3 2 0 3 3 2 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 CEH11896.1 - 2.3e-08 33.5 3.4 0.24 11.2 0.0 6.5 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 CEH11896.1 - 3.9e-07 28.7 0.0 0.011 14.0 0.0 3.9 4 0 0 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.2 CEH11896.1 - 7.2e-06 25.9 0.2 0.2 11.4 0.0 4.9 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.7 CEH11896.1 - 0.0015 18.4 0.1 0.52 10.2 0.0 3.8 3 1 0 3 3 3 1 Exportin 1-like protein Proteasom_PSMB PF10508.4 CEH11896.1 - 0.0016 16.7 0.0 0.93 7.6 0.0 3.1 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 CEH11896.1 - 0.0038 16.0 6.3 2.3 6.8 0.0 4.4 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal Ipi1_N PF12333.3 CEH11896.1 - 0.0046 16.8 0.0 52 3.8 0.0 5.1 7 0 0 7 7 5 0 Rix1 complex component involved in 60S ribosome maturation DUF3437 PF11919.3 CEH11896.1 - 0.022 14.4 0.0 0.86 9.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) ParcG PF10274.4 CEH11896.1 - 0.04 13.8 0.1 16 5.3 0.0 3.4 3 1 1 4 4 3 0 Parkin co-regulated protein UNC45-central PF11701.3 CEH11896.1 - 0.087 12.4 0.1 0.84 9.2 0.0 2.6 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central DUF2435 PF10363.4 CEH11896.1 - 0.11 12.4 0.5 1.4 8.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Homeobox PF00046.24 CEH11896.1 - 0.11 12.0 0.0 0.36 10.4 0.0 1.9 1 0 0 1 1 1 0 Homeobox domain DUF2457 PF10446.4 CEH11896.1 - 2 7.0 18.0 3.4 6.2 12.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.3 CEH11896.1 - 4.9 7.0 15.9 8.2 6.2 11.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 EBV-NA3 PF05009.7 CEH11896.1 - 7.1 5.7 5.6 12 5.0 3.9 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Thiolase_N PF00108.18 CEH11897.1 - 2.7e-85 285.5 4.3 5.1e-85 284.6 3.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CEH11897.1 - 3.9e-42 142.5 0.4 8.2e-42 141.5 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CEH11897.1 - 0.024 14.1 2.3 0.065 12.6 0.3 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Kinesin PF00225.18 CEH11898.1 - 4.7e-72 242.5 0.0 8.1e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF1319 PF07028.6 CEH11898.1 - 0.094 12.9 5.8 3.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) SlyX PF04102.7 CEH11898.1 - 3.9 7.9 9.7 1 9.7 0.3 3.4 2 1 1 3 3 3 0 SlyX WD40 PF00400.27 CEH11900.1 - 1.2e-11 43.9 0.3 4.6e-05 23.1 0.0 5.0 4 1 1 5 5 5 3 WD domain, G-beta repeat Tropomyosin_1 PF12718.2 CEH11901.1 - 9.3e-46 155.2 29.7 1.1e-45 154.9 20.6 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CEH11901.1 - 1.1e-13 50.8 32.0 1e-05 24.7 5.9 3.2 1 1 2 3 3 3 3 Tropomyosin Filament PF00038.16 CEH11901.1 - 0.00013 21.5 23.8 0.017 14.6 4.8 2.0 1 1 1 2 2 2 2 Intermediate filament protein CENP-F_leu_zip PF10473.4 CEH11901.1 - 0.0011 18.8 30.5 0.0033 17.2 6.6 3.1 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 CEH11901.1 - 0.0024 17.6 15.2 0.011 15.5 2.5 2.7 1 1 2 3 3 3 2 Laminin Domain II TMF_DNA_bd PF12329.3 CEH11901.1 - 0.004 16.9 29.4 0.0075 16.0 5.9 3.3 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 CEH11901.1 - 0.0052 16.7 29.9 0.17 11.8 5.9 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) DUF3450 PF11932.3 CEH11901.1 - 0.0056 15.9 19.6 0.056 12.6 6.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) WEMBL PF05701.6 CEH11901.1 - 0.01 14.3 29.3 0.52 8.6 20.3 2.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light ADIP PF11559.3 CEH11901.1 - 0.015 15.1 25.9 0.95 9.3 5.8 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 CEH11901.1 - 0.017 12.9 31.8 0.011 13.5 8.3 2.0 1 1 1 2 2 2 0 Myosin tail ERM PF00769.14 CEH11901.1 - 0.024 14.1 30.7 0.078 12.5 11.2 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family GAS PF13851.1 CEH11901.1 - 0.035 13.2 24.9 0.094 11.8 6.6 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding SlyX PF04102.7 CEH11901.1 - 0.039 14.3 17.9 0.074 13.4 0.9 4.1 2 2 2 4 4 4 0 SlyX Prefoldin PF02996.12 CEH11901.1 - 0.046 13.3 16.4 0.081 12.5 7.0 2.6 1 1 1 2 2 2 0 Prefoldin subunit Atg14 PF10186.4 CEH11901.1 - 0.085 11.7 23.1 0.019 13.8 11.4 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 CEH11901.1 - 0.1 12.7 13.2 0.041 14.0 4.8 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 CEH11901.1 - 0.11 12.1 26.8 0.0089 15.6 14.6 1.8 1 1 1 2 2 2 0 IncA protein DASH_Hsk3 PF08227.6 CEH11901.1 - 0.12 12.5 4.0 0.45 10.7 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like APG6 PF04111.7 CEH11901.1 - 0.14 11.2 30.3 0.95 8.4 11.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Striatin PF08232.7 CEH11901.1 - 0.15 12.3 18.7 0.52 10.6 5.8 2.1 1 1 1 2 2 2 0 Striatin family Nup54 PF13874.1 CEH11901.1 - 0.16 11.6 18.2 0.052 13.2 3.8 2.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Reo_sigmaC PF04582.7 CEH11901.1 - 0.16 11.0 4.0 0.64 9.1 1.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4164 PF13747.1 CEH11901.1 - 0.26 11.4 30.0 4.3 7.5 3.9 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) YscO PF07321.7 CEH11901.1 - 0.32 10.8 27.8 1.1 9.0 12.0 2.8 1 1 1 2 2 2 0 Type III secretion protein YscO TPR_MLP1_2 PF07926.7 CEH11901.1 - 0.39 10.4 29.1 1.4 8.6 4.3 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 CEH11901.1 - 0.45 10.3 11.9 0.12 12.1 1.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 CEH11901.1 - 0.64 8.6 24.7 3.9 6.0 9.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 CEH11901.1 - 0.77 9.5 21.2 1.7 8.3 7.8 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF641 PF04859.7 CEH11901.1 - 0.78 9.4 16.1 0.35 10.6 2.9 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ATG16 PF08614.6 CEH11901.1 - 0.91 9.3 26.1 0.83 9.4 5.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) KLRAQ PF10205.4 CEH11901.1 - 0.94 9.5 19.4 3.7 7.6 3.1 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein WXG100 PF06013.7 CEH11901.1 - 1.3 9.0 12.6 1.4 8.9 0.7 3.8 2 1 2 4 4 4 0 Proteins of 100 residues with WXG Rootletin PF15035.1 CEH11901.1 - 1.5 8.7 24.3 0.49 10.3 13.8 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion BRE1 PF08647.6 CEH11901.1 - 1.5 8.8 22.6 3.9 7.5 6.3 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase NPV_P10 PF05531.7 CEH11901.1 - 1.5 9.1 8.1 1.1 9.5 0.3 3.4 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Ax_dynein_light PF10211.4 CEH11901.1 - 1.5 8.6 23.0 1.7 8.4 4.4 2.6 1 1 2 3 3 3 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.17 CEH11901.1 - 2.3 8.2 24.2 10 6.1 9.5 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tup_N PF08581.5 CEH11901.1 - 2.4 8.4 18.8 0.55 10.4 1.5 2.8 1 1 2 3 3 3 0 Tup N-terminal V_ATPase_I PF01496.14 CEH11901.1 - 2.4 5.9 16.6 4.2 5.1 11.5 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF932 PF06067.6 CEH11901.1 - 3 7.0 15.0 0.38 10.0 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF932) Uds1 PF15456.1 CEH11901.1 - 3.2 7.7 24.8 9.3 6.2 12.9 2.6 1 1 1 2 2 2 0 Up-regulated During Septation DUF972 PF06156.8 CEH11901.1 - 3.9 7.8 19.8 5.4 7.4 5.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Cep57_CLD_2 PF14197.1 CEH11901.1 - 4.4 7.3 31.2 1.3 8.9 3.3 3.3 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Occludin_ELL PF07303.8 CEH11901.1 - 4.6 8.0 15.1 2.2 9.0 0.3 3.5 1 1 1 2 2 1 0 Occludin homology domain Rabaptin PF03528.10 CEH11901.1 - 6.8 6.6 24.4 49 3.8 7.6 3.2 1 1 1 2 2 2 0 Rabaptin DUF3584 PF12128.3 CEH11901.1 - 7.1 3.8 29.1 18 2.5 20.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF724 PF05266.9 CEH11901.1 - 7.3 6.1 23.4 13 5.2 8.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF2951 PF11166.3 CEH11901.1 - 8.8 6.2 17.3 2.5 8.0 4.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) DUF3560 PF12083.3 CEH11901.1 - 9.8 6.2 19.4 2.6 8.1 0.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3560) CENP-N PF05238.8 CEH11902.1 - 1.7e-28 99.7 0.0 3.9e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Kinetochore protein CHL4 like DUF3350 PF11830.3 CEH11902.1 - 0.17 11.9 0.7 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) CoA_transf_3 PF02515.12 CEH11903.1 - 1.7e-35 122.0 0.1 6e-35 120.2 0.0 1.9 1 1 0 2 2 2 1 CoA-transferase family III DUF4078 PF13300.1 CEH11904.1 - 4.6e-16 58.7 5.6 4.6e-16 58.7 3.9 4.4 5 1 0 5 5 5 1 Domain of unknown function (DUF4078) Tcf25 PF04910.9 CEH11905.1 - 3e-76 256.7 0.0 4.4e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 D123 PF07065.9 CEH11905.1 - 5.8e-71 239.0 0.0 1.4e-53 181.9 0.0 2.7 2 1 0 2 2 2 2 D123 Abi PF02517.11 CEH11906.1 - 2.4e-15 56.4 4.9 2.4e-15 56.4 3.4 2.0 2 0 0 2 2 2 1 CAAX protease self-immunity RhoGAP PF00620.22 CEH11907.1 - 2e-46 157.3 0.0 4.1e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 CEH11907.1 - 2.1e-14 53.4 3.0 4.1e-14 52.5 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2316 PF10078.4 CEH11907.1 - 0.094 12.7 1.2 0.82 9.7 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) EF-hand_7 PF13499.1 CEH11908.1 - 1.4e-12 47.5 5.9 5.7e-07 29.5 0.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEH11908.1 - 3.1e-07 29.6 5.3 0.00019 21.0 0.5 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CEH11908.1 - 2.2e-05 23.4 2.4 3.3 7.2 0.0 4.3 3 1 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CEH11908.1 - 0.00033 20.2 2.8 0.0084 15.7 0.3 2.7 2 1 1 3 3 3 1 EF-hand domain pair NR_Repeat PF14046.1 CEH11908.1 - 0.12 12.1 0.5 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Nuclear receptor repeat RRF PF01765.14 CEH11909.1 - 1.1e-36 125.8 0.0 2e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Ribosome recycling factor E1-E2_ATPase PF00122.15 CEH11910.1 - 4.5e-75 251.6 4.0 8.4e-75 250.7 2.8 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CEH11910.1 - 9.6e-34 117.6 0.0 3.3e-33 115.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CEH11910.1 - 6.8e-24 84.3 1.7 8.3e-24 84.1 0.1 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus HAD PF12710.2 CEH11910.1 - 1.3e-16 61.3 0.0 3.4e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEH11910.1 - 9.7e-14 51.1 0.0 3.7e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CEH11910.1 - 5.3e-13 48.2 0.0 1.2e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEH11910.1 - 0.0007 19.2 0.9 0.0025 17.4 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pox_F12L PF03337.8 CEH11910.1 - 0.27 9.0 0.0 0.45 8.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F12L protein Sad1_UNC PF07738.8 CEH11913.1 - 2.3e-25 88.9 0.0 6.7e-25 87.4 0.0 1.8 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal YycH PF07435.6 CEH11914.1 - 0.0017 17.1 8.6 0.047 12.3 0.6 2.1 2 0 0 2 2 2 2 YycH protein Ricin_B_lectin PF00652.17 CEH11914.1 - 0.029 14.3 2.5 0.28 11.2 0.3 2.5 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain FAST_2 PF08368.7 CEH11914.1 - 0.081 13.3 5.0 7.4 7.0 0.3 3.1 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 SprA-related PF12118.3 CEH11914.1 - 0.9 8.8 34.0 2.2 7.5 8.9 2.1 2 0 0 2 2 2 0 SprA-related family DUF3664 PF12406.3 CEH11914.1 - 1.8 9.2 18.8 3.6 8.2 3.2 2.5 2 0 0 2 2 2 0 Surface protein DUF4611 PF15387.1 CEH11914.1 - 6.6 6.9 15.9 6 7.0 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FYDLN_acid PF09538.5 CEH11914.1 - 8.9 6.9 11.0 20 5.8 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Dfp1_Him1_M PF08630.5 CEH11914.1 - 9 6.1 9.5 18 5.1 0.9 2.7 2 0 0 2 2 2 0 Dfp1/Him1, central region I_LWEQ PF01608.12 CEH11915.1 - 0.026 14.4 2.8 0.029 14.2 1.9 1.1 1 0 0 1 1 1 0 I/LWEQ domain Nbl1_Borealin_N PF10444.4 CEH11915.1 - 0.044 13.1 0.5 0.09 12.1 0.3 1.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal DUF1192 PF06698.6 CEH11915.1 - 0.37 10.6 2.7 0.58 10.0 0.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Sel1 PF08238.7 CEH11917.1 - 1.5e-23 82.7 42.8 3.5e-08 33.8 0.6 9.8 10 0 0 10 10 10 4 Sel1 repeat DUF1980 PF09323.5 CEH11917.1 - 0.013 15.2 0.0 0.041 13.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) FLO_LFY PF01698.11 CEH11917.1 - 0.64 8.8 7.8 0.15 10.8 0.1 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein Rft-1 PF04506.8 CEH11918.1 - 1.3e-53 182.2 0.0 6.8e-40 136.9 0.0 2.2 2 0 0 2 2 2 2 Rft protein Thymidylate_kin PF02223.12 CEH11919.1 - 1.5e-44 151.6 0.0 1.9e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 CEH11919.1 - 4.9e-05 23.3 0.0 8.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEH11919.1 - 0.0031 17.3 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CEH11919.1 - 0.0095 15.1 0.0 0.023 13.9 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_5 PF07728.9 CEH11919.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PPK2 PF03976.9 CEH11919.1 - 0.049 12.9 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) PAP2 PF01569.16 CEH11920.1 - 1.7e-21 76.2 3.5 1.7e-21 76.2 2.4 2.6 3 0 0 3 3 3 1 PAP2 superfamily KH_1 PF00013.24 CEH11920.1 - 3.9e-05 23.2 0.0 7.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CEH11920.1 - 0.00015 21.3 0.0 0.00038 20.0 0.0 1.7 1 0 0 1 1 1 1 KH domain Methyltransf_11 PF08241.7 CEH11921.1 - 3.2e-13 49.9 0.0 8.3e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEH11921.1 - 1.2e-11 44.2 0.0 1.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CEH11921.1 - 3.2e-07 30.0 0.0 4.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH11921.1 - 2.1e-06 28.1 0.0 5.4e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH11921.1 - 2.2e-05 24.2 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH11921.1 - 2.9e-05 24.3 0.0 0.0001 22.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH11921.1 - 0.00025 21.0 0.1 0.00097 19.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 CEH11921.1 - 0.0031 17.1 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 CEH11921.1 - 0.041 14.4 0.0 0.083 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 CEH11921.1 - 0.11 11.7 0.0 0.34 10.1 0.0 1.6 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain PAGK PF15284.1 CEH11922.1 - 0.056 13.1 1.5 0.091 12.5 0.2 2.0 2 0 0 2 2 2 0 Phage-encoded virulence factor DUF3043 PF11241.3 CEH11922.1 - 1.4 8.5 5.5 3.1 7.3 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) 2Fe-2S_Ferredox PF11591.3 CEH11924.1 - 0.69 9.6 3.3 1.6 8.4 2.3 1.6 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide CCT_2 PF09425.5 CEH11925.1 - 0.00057 19.3 0.4 0.0013 18.2 0.2 1.6 1 0 0 1 1 1 1 Divergent CCT motif DUF2435 PF10363.4 CEH11927.1 - 3.5e-23 81.2 0.4 1.5e-22 79.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 CEH11927.1 - 0.012 15.9 0.5 0.012 15.9 0.3 3.6 5 0 0 5 5 5 0 HEAT repeats MMS19_N PF14500.1 CEH11927.1 - 0.032 13.5 0.2 1.4 8.1 0.0 2.8 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Adaptin_N PF01602.15 CEH11927.1 - 0.036 12.3 0.2 0.093 11.0 0.0 1.7 2 0 0 2 2 2 0 Adaptin N terminal region DUF2828 PF11443.3 CEH11927.1 - 0.062 11.4 0.0 0.088 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) HEAT PF02985.17 CEH11927.1 - 0.56 10.4 3.8 8.6 6.7 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Adaptin_N PF01602.15 CEH11929.1 - 1.7e-95 320.3 6.5 1.9e-95 320.1 4.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CEH11929.1 - 5.7e-09 36.0 3.2 4.8e-07 29.7 0.2 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CEH11929.1 - 8.4e-08 32.4 4.3 0.024 14.9 0.2 3.7 2 1 0 3 3 3 3 HEAT repeats HEAT PF02985.17 CEH11929.1 - 0.0011 18.9 1.1 0.09 12.9 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 CEH11929.1 - 0.0036 17.0 0.7 0.3 10.9 0.1 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CEH11929.1 - 0.042 14.3 0.4 48 4.6 0.1 4.1 3 0 0 3 3 3 0 HEAT-like repeat CTP_synth_N PF06418.9 CEH11930.1 - 1.4e-116 388.4 0.4 1.9e-116 387.9 0.3 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CEH11930.1 - 4.9e-36 123.9 0.0 8.9e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.18 CEH11930.1 - 0.005 16.2 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Bul1_N PF04425.7 CEH11931.1 - 0.2 10.1 1.5 0.16 10.5 0.1 1.5 2 0 0 2 2 2 0 Bul1 N terminus Aldolase_II PF00596.16 CEH11932.1 - 8.7e-42 142.8 0.8 1.2e-41 142.3 0.5 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Abhydrolase_6 PF12697.2 CEH11933.1 - 9.7e-16 58.3 4.2 9.7e-16 58.3 2.9 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH11933.1 - 5e-14 52.2 0.0 1.3e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH11933.1 - 9.7e-07 28.5 0.9 0.0028 17.2 0.1 3.1 2 2 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.15 CEH11933.1 - 2e-05 24.9 0.0 5.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 CEH11933.1 - 8.9e-05 21.7 0.0 0.00023 20.4 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CEH11933.1 - 0.00021 20.9 0.0 0.00053 19.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.6 CEH11933.1 - 0.0024 16.4 0.0 0.0036 15.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.7 CEH11933.1 - 0.028 12.9 0.0 0.23 9.8 0.0 2.1 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 CEH11933.1 - 0.081 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 CEH11933.1 - 0.092 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.13 CEH11933.1 - 0.11 11.7 0.2 1.8 7.8 0.0 2.7 3 1 0 3 3 3 0 Dienelactone hydrolase family 2OG-FeII_Oxy_2 PF13532.1 CEH11934.1 - 4.6e-32 111.4 0.1 8.2e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PLA2_B PF01735.13 CEH11934.1 - 2.2e-19 68.9 0.0 3.6e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain 2OG-FeII_Oxy PF03171.15 CEH11934.1 - 9.9e-08 32.1 0.0 1.9e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.9 CEH11938.1 - 0.025 14.1 0.1 0.04 13.4 0.1 1.5 1 1 0 1 1 1 0 Amidohydrolase p450 PF00067.17 CEH11939.1 - 1.9e-42 145.3 0.0 2.5e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TBCA PF02970.11 CEH11940.1 - 2.1e-17 62.9 6.5 2.4e-17 62.7 4.5 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A MDH PF02315.11 CEH11940.1 - 0.038 13.9 0.5 0.048 13.6 0.4 1.1 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit DUF2346 PF09803.4 CEH11941.1 - 0.011 15.5 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) FTCD_C PF04961.7 CEH11941.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Hist_deacetyl PF00850.14 CEH11942.1 - 4.6e-52 177.2 0.0 6.4e-38 130.7 0.0 2.4 2 0 0 2 2 2 2 Histone deacetylase domain Pro_isomerase PF00160.16 CEH11943.1 - 1.2e-47 162.0 0.1 1.4e-47 161.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Serglycin PF04360.7 CEH11944.1 - 0.017 14.8 4.7 0.017 14.8 3.2 2.5 3 0 0 3 3 3 0 Serglycin MSA-2c PF12238.3 CEH11944.1 - 3.5 7.2 8.5 0.3 10.7 0.2 2.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c CoA_binding_3 PF13727.1 CEH11945.1 - 1.2 8.9 4.7 1.7 8.4 0.0 2.4 2 1 0 2 2 2 0 CoA-binding domain DUF1253 PF06862.7 CEH11946.1 - 2.4e-135 451.3 0.0 2.9e-135 451.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) AMP-binding PF00501.23 CEH11947.1 - 2.7e-64 217.1 0.1 5.5e-64 216.0 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CEH11947.1 - 1.8e-63 213.7 0.0 1.4e-61 207.5 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 CEH11947.1 - 1.9e-31 109.2 11.6 2.2e-30 105.8 2.3 3.6 5 0 0 5 5 4 2 short chain dehydrogenase Epimerase PF01370.16 CEH11947.1 - 7e-23 81.2 0.6 2.9e-14 53.0 0.0 3.4 3 2 0 3 3 3 2 NAD dependent epimerase/dehydratase family KR PF08659.5 CEH11947.1 - 3e-20 72.6 3.9 1.2e-16 60.8 2.1 3.6 3 0 0 3 3 3 2 KR domain adh_short_C2 PF13561.1 CEH11947.1 - 8.1e-20 71.6 0.4 2e-19 70.3 0.3 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CEH11947.1 - 6.1e-14 52.4 3.8 1.4e-06 28.4 0.7 4.0 4 0 0 4 4 4 3 NADH(P)-binding 3Beta_HSD PF01073.14 CEH11947.1 - 3.3e-10 39.1 0.2 7.3e-06 24.8 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 CEH11947.1 - 6.5e-08 33.4 0.3 2.4e-07 31.6 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 CEH11947.1 - 9.2e-08 32.2 0.0 2.3e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 CEH11947.1 - 1.7e-07 30.4 2.4 0.0011 17.8 0.0 3.5 4 0 0 4 4 4 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CEH11947.1 - 1.2e-06 27.7 1.7 0.019 13.8 0.8 3.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 CEH11947.1 - 0.0004 19.4 1.3 0.0022 17.0 0.2 2.3 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 CEH11947.1 - 0.001 18.7 1.8 0.0029 17.2 0.4 2.2 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 CEH11947.1 - 0.016 14.9 2.5 0.071 12.9 1.9 1.9 2 0 0 2 2 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 CEH11947.1 - 0.025 13.8 0.5 6.7 5.8 0.0 2.8 3 0 0 3 3 3 0 NmrA-like family Semialdhyde_dh PF01118.19 CEH11947.1 - 0.028 14.7 0.3 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ApoL PF05461.6 CEH11947.1 - 0.4 9.8 3.5 0.67 9.1 2.4 1.2 1 0 0 1 1 1 0 Apolipoprotein L CDT1 PF08839.6 CEH11948.1 - 0.001 19.0 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 DNA replication factor CDT1 like LSM PF01423.17 CEH11949.1 - 1.9e-15 56.1 0.1 2.4e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain eIF-5_eIF-2B PF01873.12 CEH11950.1 - 7.5e-42 141.9 0.0 1.1e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CEH11950.1 - 6.9e-23 80.4 2.2 6.9e-23 80.4 1.5 2.2 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon RsbRD_N PF14361.1 CEH11950.1 - 0.22 11.9 3.0 2.1 8.8 0.2 2.6 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF4611 PF15387.1 CEH11950.1 - 0.8 9.8 12.1 2 8.5 1.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Abhydrolase_6 PF12697.2 CEH11951.1 - 5.8e-17 62.3 0.2 1.1e-16 61.4 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH11951.1 - 5.9e-12 45.5 0.0 1.8e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH11951.1 - 6.9e-10 38.8 0.0 1.9e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 CEH11951.1 - 0.00012 21.5 0.1 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 CEH11951.1 - 0.0029 16.9 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CEH11951.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S10 PF00450.17 CEH11951.1 - 0.12 11.5 0.1 1.6 7.8 0.0 2.4 3 0 0 3 3 3 0 Serine carboxypeptidase FMN_dh PF01070.13 CEH11952.1 - 1.2e-106 356.5 0.0 1.4e-106 356.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 CEH11952.1 - 5.2e-08 32.1 0.8 8.5e-08 31.4 0.6 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 CEH11952.1 - 4.5e-07 29.3 0.6 7e-07 28.7 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 CEH11952.1 - 4.1e-06 26.2 0.1 0.00043 19.6 0.0 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 CEH11952.1 - 4.8e-06 25.8 1.2 0.002 17.2 0.1 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 CEH11952.1 - 2.7e-05 23.2 0.2 4.1e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 CEH11952.1 - 0.0069 15.3 0.1 0.018 14.0 0.0 1.7 1 1 0 2 2 2 1 Dihydroorotate dehydrogenase Dus PF01207.12 CEH11952.1 - 0.01 14.6 0.1 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) PcrB PF01884.12 CEH11952.1 - 0.041 13.1 0.4 3.2 6.9 0.0 2.2 1 1 1 2 2 2 0 PcrB family IGPS PF00218.16 CEH11952.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Abhydrolase_6 PF12697.2 CEH11953.1 - 2.7e-21 76.5 0.8 3.5e-21 76.1 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH11953.1 - 2.5e-12 46.8 0.3 5.8e-10 39.1 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH11953.1 - 3.1e-09 36.7 0.1 4.8e-09 36.1 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CEH11953.1 - 0.00043 20.0 0.2 0.0013 18.5 0.0 2.0 2 1 0 2 2 2 1 Putative lysophospholipase EHN PF06441.7 CEH11953.1 - 0.0046 16.8 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Corona_5a PF06336.6 CEH11953.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Coronavirus 5a protein AAA_11 PF13086.1 CEH11954.1 - 9.9e-57 192.2 0.3 1e-55 188.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 CEH11954.1 - 5e-47 159.8 0.0 8.6e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CEH11954.1 - 1.5e-09 37.7 1.1 0.076 12.5 0.1 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 CEH11954.1 - 4.6e-09 36.1 4.7 7.5e-05 22.3 0.1 3.5 3 1 1 4 4 4 2 AAA domain AAA_19 PF13245.1 CEH11954.1 - 1.9e-08 33.9 3.8 7.6e-08 31.9 0.7 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CEH11954.1 - 4.6e-06 26.8 0.0 0.00079 19.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 CEH11954.1 - 0.00012 21.1 0.6 0.18 10.7 0.0 3.0 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) UvrD_C PF13361.1 CEH11954.1 - 0.00029 20.4 0.7 0.011 15.2 0.1 2.3 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CEH11954.1 - 0.00032 20.0 0.0 0.033 13.5 0.0 2.3 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 CEH11954.1 - 0.00052 20.0 3.9 0.0026 17.7 1.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain PhoH PF02562.11 CEH11954.1 - 0.00053 19.2 0.0 0.66 9.1 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein UvrD_C_2 PF13538.1 CEH11954.1 - 0.00057 19.9 0.4 0.0019 18.3 0.1 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 CEH11954.1 - 0.00069 19.0 0.1 0.0027 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CEH11954.1 - 0.0027 17.5 0.4 0.29 10.9 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA PF00004.24 CEH11954.1 - 0.049 13.8 0.4 0.25 11.5 0.3 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) CD4-extracel PF09191.5 CEH11954.1 - 0.086 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 CD4, extracellular Toxin_52 PF15605.1 CEH11958.1 - 0.058 13.2 2.4 4.8 7.1 0.0 3.2 3 0 0 3 3 3 0 Putative toxin 52 Orthopox_A5L PF06193.6 CEH11958.1 - 0.12 12.3 3.1 0.62 9.9 0.2 2.8 2 1 0 2 2 2 0 Orthopoxvirus A5L protein-like DUF4201 PF13870.1 CEH11958.1 - 0.77 9.1 6.1 1.3 8.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Vezatin PF12632.2 CEH11958.1 - 1.6 7.7 9.6 2.4 7.1 0.1 2.8 3 0 0 3 3 3 0 Mysoin-binding motif of peroxisomes Pinin_SDK_memA PF04696.8 CEH11960.1 - 5e-07 29.3 0.9 5e-07 29.3 0.6 3.1 4 0 0 4 4 4 1 pinin/SDK/memA/ protein conserved region Smg4_UPF3 PF03467.10 CEH11961.1 - 3.3e-33 115.1 1.8 3.8e-33 114.9 0.0 2.1 2 0 0 2 2 2 1 Smg-4/UPF3 family BRCT PF00533.21 CEH11962.1 - 3.3e-07 30.3 0.0 7.5e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PNP_UDP_1 PF01048.15 CEH11962.1 - 0.067 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily PTCB-BRCT PF12738.2 CEH11962.1 - 0.073 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 twin BRCT domain Rib_recp_KP_reg PF05104.7 CEH11962.1 - 4 7.9 7.6 9.7 6.6 4.8 1.9 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region Ribonuclease_T2 PF00445.13 CEH11963.1 - 1.2e-37 129.3 0.6 1.7e-37 128.8 0.4 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DPBB_1 PF03330.13 CEH11964.1 - 1.3e-09 37.8 0.0 2.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel MMS19_N PF14500.1 CEH11966.1 - 3.1e-62 210.2 2.1 3.1e-60 203.6 0.0 3.7 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 CEH11966.1 - 9e-54 182.7 0.2 4.8e-53 180.3 0.0 2.3 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal UME PF08064.8 CEH11966.1 - 0.022 14.6 1.1 12 5.9 0.0 3.3 3 0 0 3 3 3 0 UME (NUC010) domain DUF3402 PF11882.3 CEH11967.1 - 2.5e-120 402.2 0.0 8e-119 397.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CEH11967.1 - 7.5e-42 143.1 0.0 5.3e-41 140.3 0.0 2.1 1 1 0 1 1 1 1 N1221-like protein Pterin_4a PF01329.14 CEH11967.1 - 0.014 15.1 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase Nup88 PF10168.4 CEH11968.1 - 2.6e-15 55.3 8.5 3.2e-08 31.9 0.0 3.1 3 0 0 3 3 3 3 Nuclear pore component DUF919 PF06034.6 CEH11968.1 - 0.14 11.7 3.1 0.51 9.9 2.2 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) YlqD PF11068.3 CEH11968.1 - 0.17 11.9 11.2 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 YlqD protein DUF948 PF06103.6 CEH11968.1 - 0.98 9.3 3.2 2.3 8.1 0.7 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 CEH11968.1 - 3.4 7.4 5.2 39 4.0 0.6 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF202 PF02656.10 CEH11971.1 - 0.56 10.4 4.9 0.41 10.9 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) bZIP_1 PF00170.16 CEH11972.1 - 0.06 13.3 10.5 0.051 13.5 1.9 2.8 2 1 0 2 2 2 0 bZIP transcription factor DUF607 PF04678.8 CEH11972.1 - 0.23 11.3 6.1 0.27 11.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Herpes_BLRF2 PF05812.7 CEH11972.1 - 0.31 10.8 4.3 8.3 6.2 0.3 2.8 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein CortBP2 PF09727.4 CEH11974.1 - 0.013 15.0 0.6 0.021 14.3 0.4 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 MIS13 PF08202.6 CEH11974.1 - 0.021 13.9 0.4 0.036 13.1 0.3 1.3 1 0 0 1 1 1 0 Mis12-Mtw1 protein family 3Beta_HSD PF01073.14 CEH11975.1 - 9.8e-11 40.8 0.1 1.5e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CEH11975.1 - 2.3e-09 37.5 1.6 6.8e-09 35.9 1.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CEH11975.1 - 2.4e-08 33.6 0.0 3.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CEH11975.1 - 1.5e-07 30.6 0.2 0.00092 18.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein KR PF08659.5 CEH11975.1 - 0.004 16.8 2.2 0.0079 15.8 0.8 1.9 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 CEH11975.1 - 0.0065 15.7 2.1 0.084 12.1 0.4 2.9 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.20 CEH11975.1 - 0.0072 16.2 1.6 0.0072 16.2 1.1 2.3 1 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CEH11975.1 - 0.021 13.7 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WW PF00397.21 CEH11976.1 - 0.088 12.6 0.4 0.088 12.6 0.3 2.6 3 0 0 3 3 3 0 WW domain PIN_4 PF13638.1 CEH11977.1 - 1.7e-06 28.1 0.0 3.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 PIN domain PAP1 PF08601.5 CEH11977.1 - 3.9 7.0 7.8 0.14 11.8 0.6 1.9 2 0 0 2 2 2 0 Transcription factor PAP1 Methyltransf_16 PF10294.4 CEH11978.1 - 0.018 14.5 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase ADH_N PF08240.7 CEH11981.1 - 2e-22 79.0 3.4 3.8e-22 78.1 2.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEH11981.1 - 1.2e-13 50.6 0.0 2.8e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEH11981.1 - 0.0023 17.0 0.2 0.0055 15.8 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CEH11981.1 - 0.0067 16.0 0.0 0.0067 16.0 0.0 2.6 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CEH11981.1 - 0.011 15.4 0.0 0.032 13.8 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CEH11981.1 - 0.016 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NADH_4Fe-4S PF10589.4 CEH11981.1 - 0.034 13.3 1.2 0.086 12.0 0.8 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region ELFV_dehydrog PF00208.16 CEH11981.1 - 0.051 13.1 0.1 0.098 12.2 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ApbA PF02558.11 CEH11981.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 CEH11981.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 CEH11981.1 - 0.76 9.6 2.0 2.1 8.1 1.4 1.7 1 0 0 1 1 1 0 ThiF family Sec6 PF06046.8 CEH11982.1 - 9.6e-140 466.3 0.3 1.3e-139 465.9 0.2 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 MgsA_C PF12002.3 CEH11983.1 - 3.7e-50 169.8 0.0 7.8e-50 168.8 0.0 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal TPK_catalytic PF04263.11 CEH11983.1 - 4.9e-21 74.5 0.0 1.4e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 CEH11983.1 - 2.5e-13 49.5 0.0 4.6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain RuvB_N PF05496.7 CEH11983.1 - 6.8e-13 48.2 0.0 1.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CEH11983.1 - 2.4e-10 40.7 0.1 1e-09 38.6 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CEH11983.1 - 3.3e-07 30.4 0.1 8.5e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 CEH11983.1 - 1.1e-06 28.8 0.2 4.8e-06 26.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CEH11983.1 - 2.6e-06 27.3 0.0 7.5e-06 25.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CEH11983.1 - 1.5e-05 24.7 0.1 5e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CEH11983.1 - 3.6e-05 23.0 0.1 0.016 14.3 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CEH11983.1 - 0.00013 21.9 9.3 0.0012 18.8 3.6 3.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CEH11983.1 - 0.00048 20.0 0.0 0.0017 18.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 CEH11983.1 - 0.0008 18.9 0.3 0.92 8.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 CEH11983.1 - 0.0012 19.0 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CEH11983.1 - 0.0016 17.2 0.1 0.4 9.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Sgf11 PF08209.6 CEH11983.1 - 0.0023 17.2 1.0 0.011 15.0 0.4 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) AAA_19 PF13245.1 CEH11983.1 - 0.0023 17.6 0.0 0.0099 15.6 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CEH11983.1 - 0.0024 18.6 0.0 0.0062 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CEH11983.1 - 0.0072 16.6 0.5 0.043 14.1 0.0 2.4 3 0 0 3 3 2 1 ABC transporter DUF815 PF05673.8 CEH11983.1 - 0.0096 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CEH11983.1 - 0.012 15.4 0.0 0.064 13.1 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CEH11983.1 - 0.015 14.8 0.0 0.015 14.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CEH11983.1 - 0.018 14.7 0.4 0.044 13.4 0.0 1.8 2 0 0 2 2 1 0 NACHT domain AAA_13 PF13166.1 CEH11983.1 - 0.022 13.2 0.0 0.041 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CEH11983.1 - 0.026 14.2 0.2 4.5 6.9 0.1 2.3 1 1 1 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 CEH11983.1 - 0.028 14.6 0.0 0.089 12.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase IstB_IS21 PF01695.12 CEH11983.1 - 0.028 13.8 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein cobW PF02492.14 CEH11983.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_3 PF07726.6 CEH11983.1 - 0.11 12.0 0.1 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hamartin PF04388.7 CEH11983.1 - 2.7 6.5 20.7 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Hamartin protein Med3 PF11593.3 CEH11983.1 - 7.9 5.6 21.4 1 8.5 11.3 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DCP1 PF06058.8 CEH11984.1 - 5.8e-18 65.1 0.0 8.6e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family DUF2239 PF09998.4 CEH11988.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) 2OG-FeII_Oxy_3 PF13640.1 CEH11990.1 - 0.17 12.4 2.8 0.97 9.9 0.8 2.6 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily PT-HINT PF07591.6 CEH11994.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Pretoxin HINT domain zf-C2H2_jaz PF12171.3 CEH11998.1 - 1.6e-05 24.8 4.1 0.028 14.5 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CEH11998.1 - 3.4e-05 23.9 5.2 0.034 14.4 0.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH11998.1 - 0.0049 17.1 7.1 0.024 14.9 0.9 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 CEH11998.1 - 0.0051 16.9 4.6 0.35 11.0 1.0 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 CEH11998.1 - 1.1 9.6 6.6 1 9.7 1.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Nrap PF03813.9 CEH11999.1 - 9.4e-196 652.3 0.0 1.5e-195 651.6 0.0 1.3 1 1 0 1 1 1 1 Nrap protein Sedlin_N PF04628.8 CEH12000.1 - 2.5e-25 88.8 0.0 3.5e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Sedlin, N-terminal conserved region Ribosomal_60s PF00428.14 CEH12000.1 - 6.5 7.2 11.9 3.4 8.1 0.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF663 PF04950.7 CEH12001.1 - 2.2e-84 282.9 0.0 4.9e-84 281.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CEH12001.1 - 3.6e-27 93.7 0.0 1e-26 92.2 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Peptidase_M16_C PF05193.16 CEH12002.1 - 1.6e-38 132.2 0.0 2.2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CEH12002.1 - 3.8e-21 75.4 0.0 7.8e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) WD40 PF00400.27 CEH12004.1 - 6.7e-08 32.1 0.1 4.5 7.3 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat SSP160 PF06933.6 CEH12005.1 - 5.7 4.8 9.1 9.7 4.0 6.3 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1640 PF07798.6 CEH12006.1 - 2.8e-57 193.6 1.3 3.2e-57 193.4 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.13 CEH12006.1 - 0.012 15.3 1.6 0.045 13.4 1.1 2.1 1 0 0 1 1 1 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 CEH12006.1 - 0.094 12.5 2.1 0.83 9.4 0.7 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 CEH12006.1 - 0.14 11.6 1.1 0.21 11.1 0.8 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GreA_GreB_N PF03449.10 CEH12006.1 - 0.35 10.9 6.2 0.74 9.9 2.4 2.3 1 1 0 2 2 2 0 Transcription elongation factor, N-terminal Ada_Zn_binding PF02805.11 CEH12007.1 - 5.6e-07 29.0 1.5 1.4e-06 27.7 1.1 1.7 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 CEH12007.1 - 0.037 13.8 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Mito_fiss_reg PF05308.6 CEH12007.1 - 0.15 11.3 0.0 0.15 11.3 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial fission regulator 4HBT_3 PF13622.1 CEH12009.1 - 1e-35 123.7 0.8 1.2e-35 123.4 0.6 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 CEH12009.1 - 3.8e-29 100.9 0.0 8.7e-22 77.1 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase Gly-zipper_OmpA PF13436.1 CEH12010.1 - 0.0017 18.0 14.2 0.0017 18.0 9.8 5.7 4 1 1 6 6 6 1 Glycine-zipper containing OmpA-like membrane domain DUF2098 PF09871.4 CEH12011.1 - 0.069 13.0 4.1 0.13 12.2 2.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Macoilin PF09726.4 CEH12011.1 - 0.36 9.0 14.8 0.42 8.8 10.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Orbi_VP6 PF01516.11 CEH12011.1 - 0.85 8.6 12.1 1 8.3 8.4 1.0 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF1510 PF07423.6 CEH12011.1 - 1.2 8.4 15.3 1.4 8.1 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 CEH12011.1 - 4.7 4.8 6.7 4.8 4.7 4.6 1.0 1 0 0 1 1 1 0 Ycf1 MMR1 PF08505.5 CEH12011.1 - 4.9 7.1 12.0 6.5 6.7 8.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Neur_chan_memb PF02932.11 CEH12011.1 - 5.1 6.8 8.1 6.4 6.5 5.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MIP-T3 PF10243.4 CEH12011.1 - 5.4 5.3 18.9 6.1 5.2 13.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sporozoite_P67 PF05642.6 CEH12011.1 - 5.9 4.6 12.3 6.7 4.4 8.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM60A PF15396.1 CEH12011.1 - 6.8 6.3 9.2 8.4 6.0 6.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A GMC_oxred_C PF05199.8 CEH12012.1 - 3.3e-14 53.3 0.0 3.4e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase HSF_DNA-bind PF00447.12 CEH12013.1 - 1.5e-35 121.4 0.3 2e-35 121.0 0.2 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Cdc6_C PF09079.6 CEH12013.1 - 0.0018 17.9 0.0 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 CDC6, C terminal Glyco_tranf_2_3 PF13641.1 CEH12015.1 - 2.4e-32 112.6 0.0 3.2e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CEH12015.1 - 5e-26 91.3 0.0 8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 CEH12015.1 - 3.4e-21 75.8 1.0 3.4e-21 75.8 0.7 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 CEH12015.1 - 1.4e-15 56.9 0.0 2.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 CEH12015.1 - 8.1e-06 24.4 3.6 0.00024 19.5 0.7 2.9 2 1 1 3 3 3 1 Cellulose synthase Glyco_tranf_2_2 PF10111.4 CEH12015.1 - 8.3e-05 21.7 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 UDPG_MGDP_dh_N PF03721.9 CEH12016.1 - 5.3e-56 188.9 0.0 1.8e-55 187.2 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 CEH12016.1 - 2.5e-25 88.5 0.0 5.3e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 CEH12016.1 - 5.9e-20 71.3 0.1 4.2e-15 55.7 0.0 2.8 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Saccharop_dh PF03435.13 CEH12016.1 - 0.055 12.4 0.0 0.094 11.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 CEH12016.1 - 0.11 12.1 0.0 0.33 10.5 0.0 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AcetylCoA_hyd_C PF13336.1 CEH12017.1 - 0.051 13.2 0.0 0.066 12.8 0.0 1.1 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_16 PF00722.16 CEH12018.1 - 0.025 13.8 0.1 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 EamA PF00892.15 CEH12020.1 - 8.3e-18 64.6 28.8 2.2e-09 37.4 7.6 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CEH12020.1 - 2.4 8.3 25.7 0.13 12.4 5.0 3.2 2 1 1 3 3 3 0 Multidrug resistance efflux transporter Ras PF00071.17 CEH12021.1 - 1.2e-55 187.3 0.0 1.4e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH12021.1 - 1e-19 71.1 0.0 1.6e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH12021.1 - 2.9e-14 52.6 0.0 1.2e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEH12021.1 - 3.7e-07 29.5 0.0 4.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEH12021.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEH12021.1 - 0.0017 18.3 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CEH12021.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain RRM_1 PF00076.17 CEH12023.1 - 2e-11 43.3 0.0 2.7e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH12023.1 - 5.4e-09 35.9 0.0 7.8e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH12023.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEH12023.1 - 0.0027 17.5 0.1 0.004 16.9 0.1 1.3 1 1 0 1 1 1 1 RNA binding motif COG5 PF10392.4 CEH12024.1 - 2.8e-12 46.7 6.5 8.5e-12 45.1 4.5 1.9 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Proteasome PF00227.21 CEH12025.1 - 8.7e-11 41.4 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit zf-CCHC_5 PF14787.1 CEH12030.1 - 0.26 10.7 1.2 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger GUN4 PF05419.7 CEH12033.1 - 0.044 13.5 0.2 0.058 13.2 0.1 1.2 1 0 0 1 1 1 0 GUN4-like DUF3989 PF13150.1 CEH12034.1 - 0.021 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Mur_ligase_M PF08245.7 CEH12036.1 - 0.00011 22.2 0.2 0.0028 17.7 0.1 2.7 1 1 0 1 1 1 1 Mur ligase middle domain CLASP_N PF12348.3 CEH12037.1 - 1.7e-27 96.2 0.1 3e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 CEH12037.1 - 0.59 10.3 5.9 0.31 11.2 0.6 3.4 4 0 0 4 4 4 0 HEAT repeat C2 PF00168.25 CEH12038.1 - 1.1e-17 63.5 0.0 3.4e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain Peroxidase_2 PF01328.12 CEH12039.1 - 1.2e-15 56.9 0.0 2.2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 Pkinase PF00069.20 CEH12040.1 - 3.8e-62 209.7 0.1 1.6e-41 142.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH12040.1 - 6.1e-27 94.3 0.0 1.2e-20 73.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEH12040.1 - 0.00017 20.6 0.2 0.0013 17.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CEH12040.1 - 0.0027 17.5 7.9 0.067 12.9 0.0 3.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CEH12040.1 - 0.04 12.6 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 CEH12040.1 - 0.096 11.4 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Med15 PF09606.5 CEH12040.1 - 3.6 5.6 63.9 4.9 5.2 44.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ACBP PF00887.14 CEH12041.1 - 7.9e-16 57.5 0.0 9.8e-16 57.2 0.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein DSPn PF14671.1 CEH12042.1 - 6.8e-31 107.1 0.0 2.6e-29 101.9 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CEH12042.1 - 4.4e-14 52.2 0.0 9.9e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEH12042.1 - 8.6e-06 25.2 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CEH12042.1 - 0.0006 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CEH12042.1 - 0.0077 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family SUR7 PF06687.7 CEH12043.1 - 3.3e-10 39.8 16.0 1.6e-09 37.6 10.9 2.0 1 1 0 1 1 1 1 SUR7/PalI family DuoxA PF10204.4 CEH12043.1 - 0.00079 18.5 2.7 0.00079 18.5 1.9 1.4 2 0 0 2 2 2 1 Dual oxidase maturation factor Claudin_2 PF13903.1 CEH12043.1 - 0.0056 16.3 6.9 0.016 14.8 4.5 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 CEH12043.1 - 0.017 14.3 1.0 0.035 13.3 0.7 1.4 1 0 0 1 1 1 0 Clc-like DUF3796 PF12676.2 CEH12043.1 - 0.19 11.9 1.5 0.96 9.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) Tim17 PF02466.14 CEH12044.1 - 1.2e-11 44.7 10.1 2e-11 44.0 7.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Polysacc_synt_C PF14667.1 CEH12044.1 - 0.032 14.0 0.8 0.055 13.2 0.6 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain CLU PF13236.1 CEH12045.1 - 1e-73 247.4 0.0 1.6e-73 246.7 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 CEH12045.1 - 8.9e-42 142.8 0.0 1.7e-41 141.9 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 CEH12045.1 - 3.3e-19 68.5 3.1 4.9e-09 35.9 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 CEH12045.1 - 2.9e-10 39.7 12.7 0.00063 19.5 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.1 CEH12045.1 - 5.6e-05 23.2 0.0 0.0012 18.9 0.0 2.8 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term 4HBT_3 PF13622.1 CEH12046.1 - 2.3e-34 119.2 0.1 3.4e-34 118.7 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 CEH12046.1 - 0.00015 21.3 0.1 0.0003 20.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA thioesterase FA_desaturase PF00487.19 CEH12047.1 - 6.2e-29 101.2 14.2 1.4e-15 57.4 0.2 2.3 2 0 0 2 2 2 2 Fatty acid desaturase Alpha-amylase PF00128.19 CEH12048.1 - 3.8e-25 88.9 0.0 1.7e-24 86.7 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 CEH12048.1 - 1.1e-07 30.0 0.0 0.022 12.5 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.5 CEH12048.1 - 0.0021 17.9 0.1 0.0052 16.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Alpha-amylase_C PF02806.13 CEH12048.1 - 0.03 14.4 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Med7 PF05983.6 CEH12050.1 - 4.7e-24 85.0 11.6 2.1e-13 50.3 6.1 2.3 2 0 0 2 2 2 2 MED7 protein Toxin_58 PF15536.1 CEH12050.1 - 0.074 12.8 0.1 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 58 PXA PF02194.10 CEH12050.1 - 0.26 10.8 4.2 0.068 12.7 0.5 1.7 2 0 0 2 2 2 0 PXA domain Cmc1 PF08583.5 CEH12051.1 - 2e-16 59.4 3.0 2.8e-16 59.0 2.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CEH12051.1 - 0.02 14.7 0.6 0.54 10.2 0.0 2.4 2 0 0 2 2 2 0 CHCH domain Pet191_N PF10203.4 CEH12051.1 - 0.071 13.1 0.7 12 5.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Ribosomal_L4 PF00573.17 CEH12053.1 - 1.8e-59 200.4 0.0 2.6e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF1993 PF09351.5 CEH12054.1 - 0.023 14.6 0.5 0.072 13.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) adh_short PF00106.20 CEH12057.1 - 9.5e-18 64.6 0.0 1.7e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH12057.1 - 2.1e-08 34.2 0.0 3.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH12057.1 - 3e-08 33.5 0.1 4.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CEH12057.1 - 0.016 15.2 0.2 0.9 9.5 0.1 2.4 2 0 0 2 2 2 0 NADH(P)-binding DUF2201 PF09967.4 CEH12057.1 - 0.045 13.7 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 VWA-like domain (DUF2201) Eno-Rase_NADH_b PF12242.3 CEH12057.1 - 0.19 11.5 2.1 0.23 11.2 0.6 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ABC_tran PF00005.22 CEH12058.1 - 3.5e-44 150.4 0.0 2e-25 89.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CEH12058.1 - 1e-28 100.5 23.5 7.4e-15 55.0 5.6 3.6 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 CEH12058.1 - 1.4e-06 27.6 0.1 0.017 14.3 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CEH12058.1 - 0.00027 21.0 0.3 6.4 6.6 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 CEH12058.1 - 0.00096 18.6 0.3 0.24 10.9 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 CEH12058.1 - 0.0026 18.0 7.3 0.031 14.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CEH12058.1 - 0.0029 17.0 0.1 0.69 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 CEH12058.1 - 0.0077 16.0 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 CEH12058.1 - 0.012 15.7 0.4 5.3 7.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CEH12058.1 - 0.017 14.5 0.1 4.4 6.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 CEH12058.1 - 0.037 12.9 0.8 0.72 8.7 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein SbcCD_C PF13558.1 CEH12058.1 - 0.053 13.4 0.3 3.4 7.6 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NIF PF03031.13 CEH12059.1 - 1.4e-05 24.8 0.0 0.19 11.3 0.0 3.4 3 0 0 3 3 3 3 NLI interacting factor-like phosphatase Nup88 PF10168.4 CEH12061.1 - 0.029 12.2 6.7 0.041 11.7 4.6 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF1759 PF03564.10 CEH12061.1 - 0.03 14.1 1.1 0.061 13.1 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Phytoreo_S7 PF07236.6 CEH12061.1 - 0.051 11.8 0.5 0.074 11.3 0.3 1.2 1 0 0 1 1 1 0 Phytoreovirus S7 protein Sipho_Gp157 PF05565.6 CEH12061.1 - 0.062 12.8 3.6 0.1 12.1 2.5 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Bacillus_HBL PF05791.6 CEH12061.1 - 0.095 12.0 6.3 0.47 9.7 1.1 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) BLOC1_2 PF10046.4 CEH12061.1 - 0.23 11.6 8.3 0.049 13.7 1.8 2.5 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.6 CEH12061.1 - 0.3 8.5 4.1 0.42 8.1 2.8 1.1 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.7 CEH12061.1 - 0.36 10.6 4.1 1.1 9.1 2.7 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.15 CEH12061.1 - 0.41 10.4 6.5 4.3 7.1 0.2 3.1 1 1 1 2 2 2 0 Prefoldin subunit DUF1664 PF07889.7 CEH12061.1 - 0.97 9.2 4.1 1.1 9.0 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IFT57 PF10498.4 CEH12061.1 - 1 8.0 10.9 1.5 7.4 7.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 zf-C4H2 PF10146.4 CEH12061.1 - 2.5 8.0 11.1 0.15 12.0 2.5 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein DUF3584 PF12128.3 CEH12061.1 - 4.2 4.5 20.5 5.8 4.0 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mnd1 PF03962.10 CEH12061.1 - 7.5 6.1 17.0 2.8 7.5 3.1 2.3 1 1 1 2 2 2 0 Mnd1 family UDG PF03167.14 CEH12063.1 - 0.014 14.8 0.0 0.037 13.4 0.0 1.7 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily Spc7 PF08317.6 CEH12063.1 - 0.021 13.5 3.4 0.042 12.5 2.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 CEH12063.1 - 0.14 11.7 2.1 0.34 10.4 1.5 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 CEH12063.1 - 0.34 10.8 0.1 1 9.3 0.1 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2570 PF10828.3 CEH12063.1 - 0.37 10.4 2.4 9.8 5.8 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) IncA PF04156.9 CEH12063.1 - 0.81 9.2 17.5 0.027 14.0 3.1 3.3 3 0 0 3 3 3 0 IncA protein APG6 PF04111.7 CEH12063.1 - 2.9 6.8 5.8 6.8 5.6 4.0 1.7 1 0 0 1 1 1 0 Autophagy protein Apg6 Methyltransf_16 PF10294.4 CEH12066.1 - 1.5e-12 47.3 0.0 2.3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CEH12066.1 - 0.018 14.8 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GlyL_C PF12524.3 CEH12066.1 - 8.2 6.4 6.6 5.7 6.9 0.4 3.0 3 0 0 3 3 3 0 dsDNA virus glycoprotein L C terminal RWD PF05773.17 CEH12067.1 - 2.4e-20 72.5 0.9 4.2e-20 71.7 0.1 1.8 2 0 0 2 2 2 1 RWD domain UPF0183 PF03676.9 CEH12068.1 - 1.2e-12 47.0 0.0 6.7e-12 44.6 0.0 2.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) DSPc PF00782.15 CEH12069.1 - 1.8e-16 59.9 0.0 2.4e-13 49.8 0.0 2.7 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEH12069.1 - 0.021 14.1 0.1 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF4495 PF14906.1 CEH12070.1 - 0.077 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) THUMP PF02926.12 CEH12072.1 - 1.9e-11 44.0 0.0 3.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 THUMP domain SHP PF03579.8 CEH12072.1 - 0.17 11.2 0.5 0.32 10.3 0.3 1.4 1 0 0 1 1 1 0 Small hydrophobic protein GalKase_gal_bdg PF10509.4 CEH12073.1 - 2.2e-20 71.6 0.7 4e-20 70.8 0.1 1.8 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 CEH12073.1 - 1.6e-11 44.2 0.0 4.5e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CEH12073.1 - 1.8e-11 43.9 0.9 3.8e-11 42.8 0.2 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain Glyco_hydro_43 PF04616.9 CEH12074.1 - 4.4e-10 39.1 0.0 1.3e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Frag1 PF10277.4 CEH12075.1 - 1e-30 106.8 11.4 2.5e-30 105.5 7.9 1.7 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Peptidase_S9 PF00326.16 CEH12076.1 - 4e-42 143.8 0.1 8.4e-42 142.7 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CEH12076.1 - 2.2e-05 24.4 1.4 4.9e-05 23.3 0.3 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH12076.1 - 3.8e-05 23.4 0.0 8.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 CEH12076.1 - 0.00081 17.9 0.8 0.1 11.0 0.6 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DPPIV_N PF00930.16 CEH12076.1 - 0.029 12.9 0.0 0.19 10.2 0.0 2.1 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_6 PF12697.2 CEH12077.1 - 5.9e-28 98.2 0.0 7.7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH12077.1 - 3.8e-19 69.1 0.0 1.5e-16 60.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH12077.1 - 1.3e-12 47.7 0.0 4.3e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CEH12077.1 - 4.1e-06 26.3 0.0 0.0027 17.1 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.13 CEH12077.1 - 0.00033 20.0 0.7 0.083 12.1 0.2 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CEH12077.1 - 0.0021 17.8 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CEH12077.1 - 0.0038 17.4 0.0 0.0095 16.1 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain DUF2048 PF09752.4 CEH12077.1 - 0.0082 15.0 0.1 0.55 9.0 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2048) Peptidase_S9 PF00326.16 CEH12077.1 - 0.0092 15.2 0.2 2.4 7.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 CEH12077.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.8 CEH12077.1 - 0.05 13.0 0.1 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) MOZ_SAS PF01853.13 CEH12078.1 - 1.4e-54 184.1 0.0 2.3e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family BPL_LplA_LipB PF03099.14 CEH12079.1 - 1.4e-10 41.2 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF3818 PF12825.2 CEH12080.1 - 7.2e-114 380.0 0.0 9.5e-114 379.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CEH12080.1 - 2.4e-37 127.5 0.2 4.9e-37 126.6 0.2 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 CEH12080.1 - 9.6e-07 28.5 0.0 7e-06 25.8 0.0 2.5 1 1 0 1 1 1 1 PX domain Nop14 PF04147.7 CEH12080.1 - 1.1 7.1 9.7 1.7 6.4 6.7 1.2 1 0 0 1 1 1 0 Nop14-like family Pro_isomerase PF00160.16 CEH12081.1 - 1.5e-31 109.7 0.0 2e-30 106.0 0.0 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CEH12081.1 - 1e-12 47.5 0.0 2.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH12081.1 - 1.5e-08 34.4 0.0 3.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH12081.1 - 0.00035 20.3 0.0 0.0007 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med6 PF04934.9 CEH12082.1 - 4.9e-29 100.6 0.0 6.3e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component SPAN-X PF07458.7 CEH12082.1 - 0.015 15.5 1.2 0.031 14.4 0.8 1.6 1 1 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome Pal1 PF08316.6 CEH12083.1 - 1.6e-17 64.2 0.3 1.6e-17 64.2 0.2 2.8 3 0 0 3 3 3 1 Pal1 cell morphology protein Memo PF01875.12 CEH12086.1 - 1.2e-66 224.3 0.0 1.8e-63 213.9 0.0 3.0 1 1 0 1 1 1 1 Memo-like protein Pox_RNA_Pol_19 PF05320.7 CEH12086.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Acyl-CoA_dh_1 PF00441.19 CEH12087.1 - 3e-16 59.8 2.1 1.3e-15 57.7 1.4 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEH12087.1 - 6.2e-13 48.0 0.3 1.2e-12 47.0 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CEH12087.1 - 1.4e-09 38.5 0.2 4.6e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CEH12087.1 - 2e-05 24.8 0.2 3.3e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MerR-DNA-bind PF09278.6 CEH12088.1 - 0.083 13.2 0.2 0.083 13.2 0.1 2.9 3 0 0 3 3 3 0 MerR, DNA binding zf-MYND PF01753.13 CEH12090.1 - 8.8e-10 38.2 15.0 8.8e-10 38.2 10.4 3.0 3 0 0 3 3 3 1 MYND finger SET PF00856.23 CEH12090.1 - 3.5e-09 37.1 0.1 9.6e-09 35.7 0.0 2.0 2 1 0 2 2 2 1 SET domain zf-Mss51 PF13824.1 CEH12090.1 - 7.2 6.5 14.7 14 5.6 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Sugar_tr PF00083.19 CEH12091.1 - 1.7e-83 280.7 24.4 2e-83 280.4 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH12091.1 - 1.1e-15 57.2 42.8 1.1e-12 47.3 20.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 CEH12093.1 - 1e-20 74.3 5.6 9.6e-20 71.1 3.9 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH12093.1 - 5.7e-19 68.8 0.8 2.5e-17 63.4 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH12093.1 - 8.8e-10 38.5 2.1 8.8e-10 38.5 1.4 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 CEH12093.1 - 0.072 13.0 4.2 2.2 8.2 2.6 2.6 2 1 0 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 CEH12093.1 - 0.18 11.8 1.3 0.34 10.9 0.9 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SNF2_N PF00176.18 CEH12094.1 - 1.1e-66 224.6 0.1 4.5e-53 179.9 0.1 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 CEH12094.1 - 1e-12 47.6 0.0 3.2e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 CEH12094.1 - 1.5e-07 30.9 8.8 1.5e-07 30.9 6.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEH12094.1 - 3.1e-06 26.7 7.2 3.1e-06 26.7 5.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH12094.1 - 4.8e-06 26.5 8.2 4.8e-06 26.5 5.7 2.6 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 CEH12094.1 - 5.1e-06 26.4 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CEH12094.1 - 1.6e-05 24.4 0.0 3.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 CEH12094.1 - 0.0014 18.2 9.4 0.0014 18.2 6.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CEH12094.1 - 0.0018 18.0 7.1 0.0051 16.6 5.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CEH12094.1 - 0.0023 17.7 9.6 0.0023 17.7 6.7 1.9 2 0 0 2 2 1 1 Ring finger domain Zn_Tnp_IS91 PF14319.1 CEH12094.1 - 0.0044 16.5 10.5 0.42 10.1 2.1 2.6 2 0 0 2 2 2 2 Transposase zinc-binding domain zf-RING_UBOX PF13445.1 CEH12094.1 - 0.0044 16.7 1.8 0.013 15.1 1.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CEH12094.1 - 0.049 13.4 2.9 0.11 12.2 2.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ketoacyl-synt PF00109.21 CEH12095.1 - 4.8e-27 95.0 2.0 9.3e-27 94.1 1.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 CEH12095.1 - 3.2e-16 59.1 0.0 7.4e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 CEH12095.1 - 4.1e-16 58.8 0.3 1.3e-15 57.3 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 CEH12095.1 - 0.0002 20.4 0.6 0.00055 19.0 0.2 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain Pkinase PF00069.20 CEH12098.1 - 5.9e-49 166.5 0.0 8.8e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH12098.1 - 1.5e-23 83.1 0.0 2.5e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CEH12098.1 - 0.002 17.0 0.1 0.003 16.4 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 CEH12098.1 - 0.013 15.2 0.1 0.075 12.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CEH12098.1 - 0.045 12.7 0.0 0.12 11.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.17 CEH12098.1 - 0.057 12.7 0.6 0.68 9.2 0.0 2.3 1 1 1 2 2 2 0 RIO1 family CUE PF02845.11 CEH12099.1 - 2.4e-12 46.1 0.0 3.8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain DPBB_1 PF03330.13 CEH12100.1 - 3e-08 33.5 0.1 9.2e-08 31.9 0.1 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel MAS20 PF02064.10 CEH12101.1 - 9.2e-20 70.7 0.3 2.9e-19 69.1 0.2 1.7 1 1 0 1 1 1 1 MAS20 protein import receptor WD40 PF00400.27 CEH12102.1 - 3e-43 144.2 13.1 6.4e-09 35.3 0.0 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 CEH12102.1 - 2.5e-10 39.8 4.4 7.3e-10 38.4 0.6 2.4 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 CEH12102.1 - 6.8e-08 31.0 0.2 0.087 10.9 0.0 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 F-box PF00646.28 CEH12102.1 - 0.00017 21.1 0.2 0.00017 21.1 0.1 1.9 2 0 0 2 2 2 1 F-box domain DUF2040 PF09745.4 CEH12103.1 - 2.4e-27 95.2 19.9 2.4e-27 95.2 13.8 1.8 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) RAP1 PF07218.6 CEH12103.1 - 1.7 6.6 12.0 2.3 6.1 8.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DDE_3 PF13358.1 CEH12104.1 - 3.3e-18 65.8 0.0 5.4e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2610 PF11020.3 CEH12104.1 - 0.0072 16.0 0.4 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2610) rve PF00665.21 CEH12104.1 - 0.038 14.0 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Rubrerythrin PF02915.12 CEH12104.1 - 0.13 12.6 0.4 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 Rubrerythrin HTH_Tnp_Tc3_2 PF01498.13 CEH12104.1 - 0.13 12.3 0.2 0.13 12.3 0.2 1.8 2 0 0 2 2 2 0 Transposase FYRC PF05965.9 CEH12105.1 - 0.083 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 F/Y rich C-terminus Vac_Fusion PF02346.11 CEH12107.1 - 0.035 13.5 0.1 13 5.3 0.0 2.6 2 0 0 2 2 2 0 Chordopoxvirus fusion protein LSM PF01423.17 CEH12108.1 - 2.6e-17 62.0 0.3 3.7e-17 61.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain Prefoldin_2 PF01920.15 CEH12110.1 - 1.5e-11 44.0 9.7 4.3e-07 29.6 0.4 2.2 1 1 0 2 2 2 2 Prefoldin subunit Spc24 PF08286.6 CEH12110.1 - 0.0033 17.0 8.5 0.012 15.3 2.6 2.4 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF4600 PF15372.1 CEH12110.1 - 0.0064 16.6 7.0 0.83 9.8 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4600) Seryl_tRNA_N PF02403.17 CEH12110.1 - 0.0066 16.4 12.0 0.064 13.2 3.3 2.1 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain DUF2681 PF10883.3 CEH12110.1 - 0.012 15.7 0.9 0.94 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DivIC PF04977.10 CEH12110.1 - 0.014 14.8 11.8 0.7 9.4 5.0 2.8 2 1 0 2 2 2 0 Septum formation initiator HALZ PF02183.13 CEH12110.1 - 0.13 11.9 9.1 0.6 9.8 0.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.3 CEH12110.1 - 0.16 11.8 3.8 2.6 7.9 0.7 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Rho_Binding PF08912.6 CEH12110.1 - 0.48 10.7 5.3 4.4 7.6 0.7 2.5 2 0 0 2 2 2 0 Rho Binding Laminin_II PF06009.7 CEH12110.1 - 0.49 10.1 3.4 0.71 9.6 1.2 1.9 2 0 0 2 2 2 0 Laminin Domain II DASH_Dad3 PF08656.5 CEH12110.1 - 0.76 9.5 5.1 1.8 8.2 0.8 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 Prefoldin PF02996.12 CEH12110.1 - 0.82 9.3 5.4 5.9 6.5 0.8 2.2 2 0 0 2 2 2 0 Prefoldin subunit CENP-Q PF13094.1 CEH12110.1 - 1.1 9.2 11.1 0.39 10.7 2.4 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Ax_dynein_light PF10211.4 CEH12110.1 - 1.7 8.4 8.5 1.8 8.3 2.0 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4140 PF13600.1 CEH12110.1 - 1.8 9.0 7.7 1.5 9.3 1.2 2.4 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIVA PF05103.8 CEH12110.1 - 1.8 8.6 7.3 34 4.5 4.2 2.2 1 1 0 1 1 1 0 DivIVA protein V_ATPase_I PF01496.14 CEH12110.1 - 2.3 5.9 6.2 3.3 5.4 4.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 CEH12110.1 - 2.4 8.5 12.8 13 6.1 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 CEH12110.1 - 2.8 7.8 6.9 0.75 9.6 1.5 2.1 2 0 0 2 2 2 0 Basic region leucine zipper TBPIP PF07106.8 CEH12110.1 - 3.2 7.2 10.2 4.9 6.6 0.3 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 CEH12110.1 - 6.2 6.3 12.6 33 3.9 8.8 1.9 1 1 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 CEH12110.1 - 8.4 6.4 10.2 12 5.9 2.4 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF77 PF01910.12 CEH12111.1 - 1.1e-24 85.8 0.0 1.5e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF77 SNF2_N PF00176.18 CEH12112.1 - 1.5e-31 109.3 0.0 6.4e-23 80.9 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 CEH12112.1 - 1e-07 31.4 9.7 2.2e-07 30.4 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH12112.1 - 0.00026 20.5 10.3 0.00066 19.2 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH12112.1 - 0.00037 20.4 11.1 0.0011 18.9 7.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH12112.1 - 0.0025 17.4 9.4 0.0065 16.1 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CEH12112.1 - 0.0027 17.5 11.0 0.0027 17.5 7.6 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.1 CEH12112.1 - 0.059 12.9 5.9 0.15 11.5 4.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Helicase_C PF00271.26 CEH12112.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-RING_4 PF14570.1 CEH12112.1 - 0.17 11.4 7.7 0.43 10.1 5.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CEH12112.1 - 0.74 9.5 6.0 0.76 9.5 3.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger CS PF04969.11 CEH12113.1 - 8.3e-17 61.5 0.4 1.3e-16 60.9 0.3 1.3 1 0 0 1 1 1 1 CS domain DUF4404 PF14357.1 CEH12113.1 - 0.083 13.3 0.9 0.14 12.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) FKBP_C PF00254.23 CEH12114.1 - 6.1e-33 112.7 0.0 7e-33 112.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF1_GNE PF00736.14 CEH12115.1 - 1.7e-29 101.3 1.4 1.7e-29 101.3 1.0 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CEH12115.1 - 2.7e-13 49.8 5.3 2.7e-13 49.8 3.7 2.9 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 CEH12115.1 - 0.061 13.3 0.2 0.69 9.9 0.0 2.4 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.7 CEH12115.1 - 0.074 12.7 0.8 0.12 12.0 0.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GST_C_2 PF13410.1 CEH12115.1 - 0.18 11.7 1.4 3 7.7 1.0 2.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bystin PF05291.6 CEH12116.1 - 1e-119 399.0 0.0 1.5e-119 398.4 0.0 1.1 1 0 0 1 1 1 1 Bystin RasGAP PF00616.14 CEH12117.1 - 3.7e-55 186.6 0.2 1.3e-54 184.8 0.0 2.1 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 CEH12117.1 - 1.6e-38 131.5 0.1 4.9e-38 130.0 0.1 1.9 1 0 0 1 1 1 1 RasGAP C-terminus DUF972 PF06156.8 CEH12117.1 - 0.034 14.4 5.3 1.6 9.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF972) KxDL PF10241.4 CEH12117.1 - 0.053 13.4 2.2 2.5 8.0 0.1 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein bZIP_1 PF00170.16 CEH12117.1 - 0.21 11.5 2.9 0.75 9.8 0.1 3.0 2 0 0 2 2 2 0 bZIP transcription factor MitMem_reg PF13012.1 CEH12117.1 - 0.22 11.6 4.0 8.7 6.4 0.1 2.9 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Pkinase PF00069.20 CEH12118.1 - 1.2e-65 221.2 0.0 1.6e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH12118.1 - 2e-39 135.2 0.0 3.4e-39 134.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH12118.1 - 8.6e-05 21.6 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEH12118.1 - 0.026 14.2 0.2 3.4 7.3 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family SRP-alpha_N PF04086.8 CEH12118.1 - 0.32 10.3 3.7 0.5 9.7 2.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PapD-like PF14874.1 CEH12119.1 - 2e-09 37.2 0.2 0.69 9.8 0.1 5.5 5 0 0 5 5 5 4 Flagellar-associated PapD-like DUF1090 PF06476.7 CEH12119.1 - 0.041 13.5 2.8 0.1 12.2 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) PUF PF00806.14 CEH12120.1 - 6.2e-10 37.9 0.0 0.57 9.7 0.0 6.1 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat SurE PF01975.12 CEH12121.1 - 1.3e-25 89.8 0.1 2.5e-25 88.9 0.1 1.5 1 1 0 1 1 1 1 Survival protein SurE PBP PF01161.15 CEH12123.1 - 4.2e-09 36.3 0.0 6.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF1517 PF07466.6 CEH12124.1 - 0.014 14.4 0.4 0.029 13.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Na_H_Exchanger PF00999.16 CEH12125.1 - 1.8e-39 135.3 22.2 2.5e-39 134.8 15.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peptidase_S8 PF00082.17 CEH12128.1 - 1.3e-40 139.3 1.7 1.6e-40 139.0 0.2 1.9 2 0 0 2 2 2 1 Subtilase family PA PF02225.17 CEH12128.1 - 1.4e-08 34.3 0.0 3.5e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 CEH12128.1 - 5.2e-08 33.2 0.9 5.3e-07 30.0 0.3 2.7 3 0 0 3 3 3 1 Fn3-like domain (DUF1034) Fn3-like PF14310.1 CEH12128.1 - 0.11 12.4 0.0 33 4.5 0.0 3.0 3 0 0 3 3 3 0 Fibronectin type III-like domain Pkinase PF00069.20 CEH12130.1 - 3.5e-45 154.2 0.0 2.8e-42 144.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH12130.1 - 4.4e-13 48.8 0.0 1.1e-11 44.3 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.9 CEH12130.1 - 0.0012 17.9 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEH12130.1 - 0.0042 16.8 0.5 0.088 12.5 0.2 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Ytp1 PF10355.4 CEH12131.1 - 1.3e-71 241.0 12.3 1.3e-71 241.0 8.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CEH12131.1 - 5.9e-23 80.4 0.6 5.9e-23 80.4 0.4 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) COPR5 PF15340.1 CEH12131.1 - 0.11 12.8 1.4 0.18 12.1 1.0 1.3 1 0 0 1 1 1 0 Cooperator of PRMT5 family DUF106 PF01956.11 CEH12131.1 - 0.53 9.8 2.2 1 8.8 0.0 2.6 3 0 0 3 3 3 0 Integral membrane protein DUF106 Mg_trans_NIPA PF05653.9 CEH12132.1 - 2e-25 89.4 6.2 3.2e-13 49.3 1.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 CEH12132.1 - 0.032 14.4 16.7 0.028 14.6 2.9 2.5 2 0 0 2 2 2 0 Multidrug resistance efflux transporter EamA PF00892.15 CEH12132.1 - 0.15 12.1 18.4 0.99 9.4 4.4 2.5 2 0 0 2 2 2 0 EamA-like transporter family ILVD_EDD PF00920.16 CEH12133.1 - 6.9e-189 628.5 4.9 8e-189 628.3 3.4 1.0 1 0 0 1 1 1 1 Dehydratase family Kinesin PF00225.18 CEH12134.1 - 2e-103 345.6 0.2 5.7e-103 344.1 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain PspB PF06667.7 CEH12134.1 - 2.1 8.3 8.2 0.7 9.8 0.1 3.7 3 0 0 3 3 3 0 Phage shock protein B LRR_4 PF12799.2 CEH12136.1 - 7.5e-17 60.5 2.2 1e-05 24.9 0.0 5.2 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) CAP_GLY PF01302.20 CEH12136.1 - 6.5e-15 54.5 0.2 1e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 CAP-Gly domain LRR_8 PF13855.1 CEH12136.1 - 2.1e-12 46.5 14.4 1.8e-06 27.6 1.3 5.0 4 1 2 6 6 6 4 Leucine rich repeat LRR_6 PF13516.1 CEH12136.1 - 2.7e-07 29.9 8.4 1.5 9.1 0.2 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 CEH12136.1 - 1e-05 24.8 5.8 1.8 8.8 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.1 CEH12136.1 - 0.00089 18.8 0.0 0.062 12.8 0.0 2.8 2 1 1 3 3 3 1 Leucine-rich repeat LRR_7 PF13504.1 CEH12136.1 - 0.0015 18.4 8.4 4.7 7.8 0.2 6.1 5 1 0 5 5 5 2 Leucine rich repeat PRP1_N PF06424.7 CEH12137.1 - 0.04 14.2 0.8 0.058 13.7 0.5 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Thioredoxin PF00085.15 CEH12137.1 - 0.045 13.4 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin TAFH PF07531.9 CEH12140.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 NHR1 homology to TAF DivIC PF04977.10 CEH12140.1 - 0.42 10.1 6.3 0.23 10.9 1.3 2.3 2 0 0 2 2 2 0 Septum formation initiator OmdA PF13376.1 CEH12142.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DEAD_2 PF06733.10 CEH12142.1 - 0.076 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 DEAD_2 MIF4G PF02854.14 CEH12145.1 - 2.3e-51 174.1 0.0 2.2e-30 105.6 0.0 3.2 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.9 CEH12145.1 - 2.9e-27 95.5 6.7 2.9e-27 95.5 4.7 1.9 2 0 0 2 2 2 1 Up-frameshift suppressor 2 RNase_PH PF01138.16 CEH12146.1 - 2.5e-10 40.7 0.0 4.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Glyco_hydro_cc PF11790.3 CEH12147.1 - 3.8e-44 150.8 0.0 4.6e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DEAD PF00270.24 CEH12148.1 - 2.2e-39 134.6 0.0 3.4e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH12148.1 - 2.6e-22 78.4 0.0 5.7e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH12148.1 - 2.1e-05 24.4 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CEH12148.1 - 0.013 15.2 0.1 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CEH12148.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuBisCO_large PF00016.15 CEH12148.1 - 0.061 12.1 1.9 0.1 11.4 1.3 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain SIS_2 PF13580.1 CEH12149.1 - 1.1e-11 44.6 0.0 2.7e-11 43.3 0.0 1.7 1 1 0 1 1 1 1 SIS domain SIS PF01380.17 CEH12149.1 - 8.3e-09 35.1 1.2 1.3e-07 31.3 0.0 2.9 3 0 0 3 3 3 1 SIS domain Flavoprotein PF02441.14 CEH12149.1 - 0.046 13.3 0.2 0.089 12.4 0.1 1.5 1 0 0 1 1 1 0 Flavoprotein UDG PF03167.14 CEH12151.1 - 2.1e-14 53.2 0.1 5.7e-14 51.8 0.0 1.7 1 1 1 2 2 2 1 Uracil DNA glycosylase superfamily Herpes_UL32 PF06070.6 CEH12152.1 - 1.3 7.3 19.0 1.6 7.0 13.2 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 HD PF01966.17 CEH12153.1 - 5.2e-05 23.2 0.1 0.00014 21.8 0.1 1.7 1 1 0 1 1 1 1 HD domain DUF1484 PF07363.6 CEH12153.1 - 0.05 13.9 0.0 0.092 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) Di19_C PF14571.1 CEH12153.1 - 0.14 12.5 0.2 0.29 11.4 0.0 1.6 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal RhoGAP PF00620.22 CEH12154.1 - 1.2e-34 119.1 0.0 2e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 CEH12154.1 - 0.019 13.8 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) RNB PF00773.14 CEH12155.1 - 1.6e-95 320.1 0.0 2.3e-95 319.6 0.0 1.2 1 0 0 1 1 1 1 RNB domain KAAG1 PF15354.1 CEH12156.1 - 0.052 13.8 0.5 0.17 12.2 0.4 1.9 1 0 0 1 1 1 0 Kidney-associated antigen 1 Glyco_hydro_3 PF00933.16 CEH12157.1 - 1.9e-76 256.9 0.0 3.1e-76 256.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CEH12157.1 - 2.5e-49 167.8 0.1 1.2e-48 165.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CEH12157.1 - 1.9e-20 72.5 0.0 4.9e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF448 PF04296.8 CEH12158.1 - 9.2e-05 21.9 0.3 0.13 11.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF448) tRNA-synt_2d PF01409.15 CEH12159.1 - 5.5e-86 287.7 0.0 7.7e-86 287.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CEH12159.1 - 3.5e-06 26.7 0.0 6.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 CEH12159.1 - 2.1e-05 23.4 0.7 0.0017 17.2 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) zf-TFIIIC PF12660.2 CEH12160.1 - 6.1e-13 48.5 1.6 1.5e-12 47.3 1.1 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 CEH12160.1 - 6.4e-07 29.2 0.0 1.8e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Uso1_p115_head PF04869.9 CEH12162.1 - 8.1e-49 166.0 0.0 1.6e-48 165.0 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 CEH12162.1 - 0.0077 16.1 32.7 0.0077 16.1 22.6 2.8 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region DDHD PF02862.12 CEH12163.1 - 8.7e-39 133.6 10.7 1e-38 133.4 0.0 3.5 3 1 0 3 3 3 2 DDHD domain WWE PF02825.15 CEH12163.1 - 3.4e-05 23.1 0.1 0.023 14.0 0.0 2.6 2 0 0 2 2 2 2 WWE domain Abhydrolase_5 PF12695.2 CEH12163.1 - 0.057 13.1 0.0 0.21 11.3 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1358 PF07096.6 CEH12163.1 - 0.11 12.1 0.0 0.74 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) PAP2 PF01569.16 CEH12164.1 - 1.2e-08 34.6 19.7 4.5e-07 29.5 13.6 2.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 CEH12164.1 - 1.8e-05 24.3 9.9 3.2e-05 23.5 6.9 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 CEH12164.1 - 0.0023 18.1 4.4 0.0081 16.4 3.0 1.9 1 0 0 1 1 1 1 PAP2 superfamily C-terminal Na_Ca_ex PF01699.19 CEH12165.1 - 2e-42 144.1 27.9 1.9e-21 76.1 5.8 2.5 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF485 PF04341.7 CEH12165.1 - 5.9 6.6 9.8 0.71 9.6 0.0 3.9 3 1 0 4 4 4 0 Protein of unknown function, DUF485 GATA PF00320.22 CEH12166.1 - 3.4e-13 48.6 3.9 6.8e-13 47.7 2.7 1.5 1 0 0 1 1 1 1 GATA zinc finger SEP PF08059.8 CEH12167.1 - 2.5e-23 82.1 0.0 4.2e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 CEH12167.1 - 9.8e-18 64.0 0.0 1.8e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CEH12167.1 - 4.9e-13 48.3 0.3 8.7e-13 47.5 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain Stm1_N PF09598.5 CEH12167.1 - 2.6 8.8 7.6 0.48 11.1 0.1 3.2 3 0 0 3 3 3 0 Stm1 Abhydrolase_6 PF12697.2 CEH12169.1 - 4.6e-13 49.5 4.0 1e-12 48.4 1.2 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH12169.1 - 3.1e-06 27.0 0.1 5.7e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CEH12170.1 - 2.5e-25 89.0 0.0 3.8e-25 88.4 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CEH12170.1 - 1.1e-10 41.4 0.0 1.8e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH12170.1 - 3e-06 26.9 0.0 0.0084 15.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEH12170.1 - 3.8e-05 23.6 0.0 0.086 12.7 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Pkinase PF00069.20 CEH12171.1 - 4.8e-10 39.0 0.0 8.2e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CEH12171.1 - 0.00088 19.0 0.0 0.0023 17.7 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CEH12171.1 - 0.014 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CEH12171.1 - 0.037 12.8 0.0 0.052 12.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 CEH12171.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RRM_1 PF00076.17 CEH12174.1 - 9.8e-14 50.7 0.0 1.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH12174.1 - 2.8e-09 36.8 0.0 4.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH12174.1 - 5.5e-08 32.5 0.0 8.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.1 CEH12175.1 - 7.7e-31 107.0 38.9 1e-30 106.6 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease CusF_Ec PF11604.3 CEH12176.1 - 0.18 11.6 0.5 8.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Copper binding periplasmic protein CusF CAF1 PF04857.15 CEH12177.1 - 1.3e-65 221.3 0.0 1.9e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Alpha_GJ PF03229.8 CEH12177.1 - 0.27 11.5 8.5 0.44 10.8 5.9 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J Antimicrobial10 PF08105.6 CEH12178.1 - 0.011 15.2 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 Metchnikowin family Mito_carr PF00153.22 CEH12180.1 - 1.2e-65 217.2 4.4 1.5e-22 79.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mmp37 PF09139.6 CEH12181.1 - 7.6e-108 360.4 0.0 9.1e-108 360.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 AAA_33 PF13671.1 CEH12182.1 - 3.6e-22 78.7 3.1 1e-21 77.3 0.8 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CEH12182.1 - 5.1e-05 23.5 0.1 0.1 12.9 0.0 2.3 1 1 1 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CEH12182.1 - 0.00028 20.0 0.0 0.17 10.9 0.0 2.2 1 1 1 2 2 2 2 Zeta toxin KTI12 PF08433.5 CEH12182.1 - 0.00045 19.5 1.4 0.15 11.2 0.9 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 CEH12182.1 - 0.00058 19.9 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEH12182.1 - 0.0043 17.8 0.4 0.046 14.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEH12182.1 - 0.005 16.8 0.6 0.0068 16.4 0.4 1.3 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 CEH12182.1 - 0.032 14.7 0.0 0.068 13.6 0.0 1.6 1 1 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 CEH12182.1 - 0.043 14.1 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter CobU PF02283.11 CEH12182.1 - 0.052 12.9 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase NACHT PF05729.7 CEH12182.1 - 0.12 11.9 0.1 0.33 10.5 0.0 1.8 3 0 0 3 3 3 0 NACHT domain GRIM-19 PF06212.7 CEH12183.1 - 1.3e-34 118.6 0.0 1.5e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein ACBP PF00887.14 CEH12186.1 - 1.4e-30 104.7 0.0 1.8e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein DUF1889 PF08986.5 CEH12186.1 - 0.016 15.3 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) Tox-REase-5 PF15648.1 CEH12186.1 - 0.096 12.9 0.2 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 Kelch_5 PF13854.1 CEH12187.1 - 2.9e-12 46.2 0.5 0.0051 16.7 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 CEH12187.1 - 9.9e-10 38.1 0.3 0.11 12.7 0.0 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CEH12187.1 - 3.5e-08 33.0 5.3 0.077 12.7 0.1 5.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CEH12187.1 - 2.1e-05 24.5 12.5 0.0019 18.2 0.0 6.6 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CEH12187.1 - 0.00024 20.7 0.0 10 6.0 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 CEH12187.1 - 0.0025 17.3 0.0 3.6 7.2 0.0 3.5 3 1 0 3 3 3 2 Kelch motif Metallophos PF00149.23 CEH12188.1 - 7.1e-06 25.5 0.2 1.6e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Clat_adaptor_s PF01217.15 CEH12189.1 - 3.2e-54 182.4 0.1 3.8e-54 182.2 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GTP_EFTU PF00009.22 CEH12190.1 - 7.2e-55 185.3 0.1 1.1e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CEH12190.1 - 9.1e-37 125.2 0.0 2.2e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CEH12190.1 - 2.9e-17 62.5 0.6 2.9e-17 62.5 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CEH12190.1 - 2.8e-05 23.6 0.2 6.8e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CEH12190.1 - 0.0058 16.5 0.4 0.021 14.7 0.3 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CEH12190.1 - 0.022 14.2 0.1 4 7.0 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain LETM1 PF07766.8 CEH12193.1 - 1e-18 67.3 0.1 4.8e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 LETM1-like protein Peptidase_M41 PF01434.13 CEH12194.1 - 9.9e-73 244.1 0.9 9.9e-73 244.1 0.7 1.5 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 CEH12194.1 - 1.1e-43 148.5 0.0 5.8e-43 146.2 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CEH12194.1 - 1.7e-12 47.4 0.0 4.4e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 CEH12194.1 - 0.00026 21.1 0.0 0.18 11.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEH12194.1 - 0.0011 19.7 0.1 0.0058 17.4 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 CEH12194.1 - 0.0031 17.2 0.4 0.011 15.4 0.3 2.0 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 CEH12194.1 - 0.0032 16.2 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 CEH12194.1 - 0.004 16.8 0.3 0.07 12.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CEH12194.1 - 0.0085 15.1 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CEH12194.1 - 0.03 13.7 0.4 0.097 12.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CEH12194.1 - 0.035 13.5 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TetR_C PF02909.12 CEH12194.1 - 0.057 13.0 0.8 4 7.0 0.3 2.7 2 0 0 2 2 2 0 Tetracyclin repressor, C-terminal all-alpha domain AAA_16 PF13191.1 CEH12194.1 - 0.087 12.8 0.1 0.087 12.8 0.1 3.4 3 2 2 5 5 5 0 AAA ATPase domain Aminotran_1_2 PF00155.16 CEH12195.1 - 6.9e-34 117.3 0.0 1.9e-33 115.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CEH12195.1 - 0.00011 20.6 0.0 0.00025 19.4 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CEH12195.1 - 0.022 13.9 0.0 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CEH12195.1 - 0.086 11.8 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family HABP4_PAI-RBP1 PF04774.10 CEH12196.1 - 4.6e-05 23.8 1.9 4.6e-05 23.8 1.3 4.3 2 2 3 5 5 5 1 Hyaluronan / mRNA binding family Stm1_N PF09598.5 CEH12196.1 - 0.042 14.5 1.9 0.042 14.5 1.3 5.6 3 3 0 3 3 3 0 Stm1 Mito_carr PF00153.22 CEH12197.1 - 9.5e-46 153.4 9.9 2.8e-17 62.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-CHY PF05495.7 CEH12198.1 - 3.3e-16 59.1 13.6 4.8e-16 58.6 9.5 1.2 1 0 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.1 CEH12198.1 - 0.0018 17.6 2.7 0.17 11.3 0.6 2.4 2 0 0 2 2 2 1 Cysteine-rich KTR zf-ribbon_3 PF13248.1 CEH12198.1 - 0.0053 15.9 4.9 0.17 11.1 1.0 2.7 2 1 0 2 2 2 1 zinc-ribbon domain zf-RING_3 PF14369.1 CEH12198.1 - 0.0093 15.9 2.1 0.0093 15.9 1.4 2.7 2 1 0 2 2 2 1 zinc-finger Trm112p PF03966.11 CEH12198.1 - 0.011 16.1 2.3 0.093 13.1 0.4 2.6 2 1 0 2 2 2 0 Trm112p-like protein zinc_ribbon_5 PF13719.1 CEH12198.1 - 0.011 15.2 2.0 0.011 15.2 1.4 3.4 2 2 1 3 3 3 0 zinc-ribbon domain Elf1 PF05129.8 CEH12198.1 - 0.014 15.0 8.1 0.032 13.9 2.3 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 CEH12198.1 - 0.02 14.6 9.6 0.61 9.9 4.6 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 CEH12198.1 - 0.03 14.0 2.1 0.03 14.0 1.4 3.6 2 2 1 3 3 3 0 zinc-ribbon domain C1_4 PF07975.7 CEH12198.1 - 0.073 13.0 7.3 0.14 12.1 0.7 2.7 2 1 1 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 CEH12198.1 - 0.092 12.7 9.6 0.11 12.4 0.9 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 CEH12198.1 - 0.46 10.0 8.2 0.26 10.8 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 CEH12198.1 - 0.49 10.2 10.2 0.31 10.8 4.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon DUF3797 PF12677.2 CEH12198.1 - 0.49 10.0 0.1 0.49 10.0 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) HypA PF01155.14 CEH12198.1 - 0.54 9.9 8.0 4.2 7.1 5.6 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-H2C2_2 PF13465.1 CEH12198.1 - 2.5 8.5 6.1 40 4.7 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Evr1_Alr PF04777.8 CEH12198.1 - 5.6 6.9 8.1 46 4.0 5.5 2.2 1 1 1 2 2 2 0 Erv1 / Alr family Cys_rich_CPXG PF14255.1 CEH12198.1 - 8.3 6.3 8.3 12 5.7 0.3 3.0 2 1 1 3 3 3 0 Cysteine-rich CPXCG zf-FPG_IleRS PF06827.9 CEH12198.1 - 8.6 6.1 9.9 0.079 12.6 1.0 2.0 2 0 0 2 2 1 0 Zinc finger found in FPG and IleRS zf-C2HC_2 PF13913.1 CEH12198.1 - 8.7 6.1 9.0 1.6 8.5 0.1 2.7 3 0 0 3 3 2 0 zinc-finger of a C2HC-type LIP PF03583.9 CEH12199.1 - 2.4e-59 200.9 0.1 3.4e-59 200.4 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Piwi PF02171.12 CEH12201.1 - 1.2e-69 234.6 0.0 1.6e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CEH12201.1 - 8.6e-19 67.1 0.0 3.9e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 PAZ domain DUF1785 PF08699.5 CEH12201.1 - 3.6e-13 48.6 0.1 1.2e-12 46.9 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Metal_resist PF13801.1 CEH12201.1 - 0.93 9.4 8.3 0.49 10.4 2.3 2.8 3 0 0 3 3 3 0 Heavy-metal resistance NST1 PF13945.1 CEH12202.1 - 0.18 11.8 1.7 0.21 11.6 1.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator PHD PF00628.24 CEH12203.1 - 7.9e-11 41.4 8.3 1.6e-10 40.5 5.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.3 CEH12203.1 - 0.0063 16.0 0.3 0.0063 16.0 0.2 2.5 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain C1_1 PF00130.17 CEH12203.1 - 0.032 13.9 1.9 0.089 12.5 1.3 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mucin PF01456.12 CEH12204.1 - 0.0049 16.6 5.1 0.0049 16.6 3.5 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein SSP160 PF06933.6 CEH12204.1 - 0.64 7.9 15.1 0.9 7.4 10.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CAF-1_p150 PF11600.3 CEH12204.1 - 2.9 7.1 48.7 6.4 6.0 33.7 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SCP2 PF02036.12 CEH12205.1 - 7.7e-23 80.7 0.8 1e-22 80.3 0.6 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CEH12205.1 - 5.2e-05 23.2 0.3 7.2e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Rep_fac-A_C PF08646.5 CEH12205.1 - 0.042 13.5 0.5 0.14 11.8 0.2 1.7 1 1 1 2 2 2 0 Replication factor-A C terminal domain Cation_efflux PF01545.16 CEH12206.1 - 1.3e-75 254.1 8.7 7.6e-75 251.6 6.0 1.8 1 1 0 1 1 1 1 Cation efflux family MerC PF03203.9 CEH12206.1 - 0.25 11.7 7.0 0.39 11.0 0.1 3.1 2 1 1 3 3 3 0 MerC mercury resistance protein Glutaredoxin PF00462.19 CEH12207.1 - 3.6e-20 71.6 0.0 7.8e-19 67.4 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CEH12207.1 - 2.2e-13 49.7 0.0 3.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CEH12207.1 - 0.0038 17.3 0.0 0.11 12.5 0.0 2.5 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CEH12207.1 - 0.023 14.4 0.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain Phosducin PF02114.11 CEH12207.1 - 0.03 13.0 0.0 0.052 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosducin TrbC_Ftype PF09673.5 CEH12207.1 - 0.086 12.4 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_2 PF13098.1 CEH12207.1 - 0.12 12.6 0.0 4.3 7.5 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin-like domain KH_1 PF00013.24 CEH12208.1 - 1.1e-08 34.5 0.1 2e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 CEH12208.1 - 0.00056 19.4 0.8 0.0073 15.9 0.2 2.5 2 0 0 2 2 2 1 KH domain DUF2360 PF10152.4 CEH12208.1 - 0.78 10.0 12.3 3 8.0 3.5 2.7 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) SNF2_N PF00176.18 CEH12210.1 - 1.9e-53 181.2 0.1 1.4e-26 92.9 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CEH12210.1 - 6.9e-10 38.6 4.5 1.6e-09 37.4 3.1 1.7 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 CEH12210.1 - 1e-09 38.1 0.0 5.6e-09 35.7 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 CEH12210.1 - 5e-09 36.0 6.2 9.7e-09 35.1 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH12210.1 - 1.5e-07 31.0 3.9 2.7e-07 30.1 2.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEH12210.1 - 3.6e-07 29.7 2.8 6.2e-07 28.9 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEH12210.1 - 1.4e-06 27.8 7.6 3.3e-06 26.6 5.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CEH12210.1 - 2.1e-06 27.2 6.3 4e-06 26.3 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CEH12210.1 - 9.5e-05 22.1 7.9 0.00018 21.2 5.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CEH12210.1 - 0.00062 19.8 0.3 0.0018 18.3 0.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 CEH12210.1 - 0.018 14.5 3.4 0.043 13.3 2.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 CEH12210.1 - 0.056 13.2 2.3 0.17 11.6 1.6 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 CEH12210.1 - 0.062 12.7 3.3 1.9 7.9 2.6 2.3 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.1 CEH12210.1 - 0.17 11.5 2.3 0.33 10.5 1.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SET PF00856.23 CEH12211.1 - 7e-22 78.4 0.1 1.1e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.11 CEH12211.1 - 1.3e-14 54.3 4.9 1.3e-14 54.3 3.4 2.0 2 0 0 2 2 2 1 Pre-SET motif HAD_2 PF13419.1 CEH12212.1 - 1.2e-14 54.9 0.0 2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEH12212.1 - 1.7e-08 35.1 0.0 4.1e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEH12212.1 - 7.3e-08 32.0 0.0 1.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CEH12212.1 - 0.041 14.0 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NPR3 PF03666.8 CEH12215.1 - 2.4e-66 224.1 0.0 1.8e-34 119.1 0.0 3.0 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 ATP-synt_8 PF00895.15 CEH12215.1 - 0.06 13.5 0.4 0.15 12.3 0.3 1.6 1 0 0 1 1 1 0 ATP synthase protein 8 Herpes_UL17 PF04559.7 CEH12218.1 - 0.82 8.1 13.6 0.44 9.0 1.5 2.2 2 0 0 2 2 2 0 Herpesvirus UL17 protein E1-E2_ATPase PF00122.15 CEH12220.1 - 1.1e-62 211.0 2.5 1.1e-62 211.0 1.7 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEH12220.1 - 3.3e-30 104.9 2.5 3.3e-30 104.9 1.7 2.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEH12220.1 - 5.3e-29 102.1 0.0 7.9e-23 81.9 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEH12220.1 - 7.2e-18 63.8 1.1 1.6e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CEH12220.1 - 2.6e-14 52.9 0.0 7.1e-14 51.5 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEH12220.1 - 1.1e-08 35.4 0.5 4.5e-08 33.4 0.1 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEH12220.1 - 1.8e-07 31.0 0.1 6.3e-05 22.6 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF543 PF04418.7 CEH12221.1 - 1.1e-15 57.3 0.1 4.5e-15 55.3 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF543) DUF883 PF05957.8 CEH12221.1 - 0.007 16.7 1.0 0.11 12.9 0.4 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) GCV_T PF01571.16 CEH12222.1 - 1.3e-61 207.6 0.1 1.8e-61 207.1 0.1 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CEH12222.1 - 1.8e-24 85.5 0.2 5.2e-24 84.1 0.1 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CEH12222.1 - 0.0018 18.1 0.1 0.0049 16.7 0.0 1.8 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family Cutinase PF01083.17 CEH12223.1 - 4.9e-27 94.8 0.1 6.8e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 CEH12223.1 - 1.3e-07 31.4 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold PE-PPE PF08237.6 CEH12223.1 - 1.5e-06 27.7 0.1 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.20 CEH12223.1 - 9.9e-06 25.2 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CEH12223.1 - 2.4e-05 24.3 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH12223.1 - 0.0089 15.7 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEH12223.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3089 PF11288.3 CEH12223.1 - 0.014 14.5 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) VWA_2 PF13519.1 CEH12223.1 - 0.022 14.8 0.1 0.083 12.9 0.0 1.8 1 1 1 2 2 2 0 von Willebrand factor type A domain VirJ PF06057.6 CEH12223.1 - 0.052 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.15 CEH12223.1 - 0.085 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain ATP-synt_10 PF05176.9 CEH12224.1 - 1.7e-60 204.3 0.0 2.1e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Peptidase_M43 PF05572.8 CEH12225.1 - 4.3e-21 75.1 0.0 8.2e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 CEH12225.1 - 1.2e-05 25.4 0.4 2e-05 24.7 0.3 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CEH12225.1 - 2.6e-05 24.2 0.8 3.9e-05 23.6 0.5 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 CEH12225.1 - 7.9e-05 23.1 0.2 0.00022 21.7 0.2 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CEH12225.1 - 0.0003 20.3 1.3 0.01 15.3 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 CEH12225.1 - 0.0017 17.7 5.1 0.02 14.2 3.6 2.1 1 1 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M7 PF02031.11 CEH12225.1 - 0.0051 16.5 1.0 0.013 15.1 0.7 1.8 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family adh_short_C2 PF13561.1 CEH12227.1 - 1.3e-21 77.5 0.1 1.2e-20 74.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEH12227.1 - 2.5e-05 24.2 0.2 0.00019 21.3 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 CEH12228.1 - 6.5e-38 130.8 0.0 1.2e-37 129.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain MaoC_dehydratas PF01575.14 CEH12228.1 - 7.2e-31 106.1 0.1 1.4e-30 105.1 0.1 1.4 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 CEH12228.1 - 4.9e-30 103.0 0.3 1.4e-29 101.6 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 CEH12228.1 - 1e-08 35.0 0.0 1.2e-07 31.5 0.0 2.5 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Mito_carr PF00153.22 CEH12229.1 - 2e-60 200.4 4.8 6.7e-24 83.4 0.0 3.8 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CEH12229.1 - 0.0012 18.9 0.3 0.022 14.9 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CEH12229.1 - 0.0029 17.3 0.3 0.012 15.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CEH12229.1 - 0.029 13.6 0.1 0.1 11.9 0.1 2.0 2 0 0 2 2 2 0 EF hand PPTA PF01239.17 CEH12230.1 - 9.8e-43 141.7 6.4 1.6e-08 33.5 0.4 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF572 PF04502.8 CEH12230.1 - 0.02 14.1 8.8 0.032 13.4 6.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) TPR_17 PF13431.1 CEH12230.1 - 0.098 12.9 0.0 31 5.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Zip PF02535.17 CEH12230.1 - 1.3 7.9 9.8 1.9 7.4 6.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 CEH12230.1 - 1.9 8.3 4.1 2.8 7.7 2.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CEH12230.1 - 2.6 5.6 5.5 3.4 5.2 3.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ArfGap PF01412.13 CEH12232.1 - 5.6e-40 135.7 0.2 8.4e-40 135.2 0.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRN7 PF11781.3 CEH12232.1 - 0.3 10.6 1.3 0.56 9.7 0.9 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 NIR_SIR PF01077.17 CEH12234.1 - 7.5e-41 139.1 0.0 1.9e-37 128.0 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 CEH12234.1 - 3.4e-29 100.2 0.0 2.1e-14 52.8 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 CEH12234.1 - 1.7e-26 92.9 0.0 3.1e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 CEH12234.1 - 4.2e-07 29.7 0.1 8.7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Fungal_trans PF04082.13 CEH12237.1 - 4.6e-07 28.9 0.0 8.9e-07 28.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSP90 PF00183.13 CEH12237.1 - 0.069 11.5 4.5 0.098 11.0 3.1 1.1 1 0 0 1 1 1 0 Hsp90 protein Ycf1 PF05758.7 CEH12237.1 - 0.33 8.5 1.0 0.49 8.0 0.7 1.1 1 0 0 1 1 1 0 Ycf1 Aminotran_3 PF00202.16 CEH12238.1 - 3.1e-22 78.8 0.0 4.8e-15 55.2 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class-III V-ATPase_H_N PF03224.9 CEH12241.1 - 1.1e-63 215.3 0.0 1.2e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CEH12242.1 - 3.3e-24 85.0 0.1 3.6e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_2 PF13646.1 CEH12242.1 - 0.0094 16.2 0.2 0.036 14.3 0.2 1.8 1 1 0 1 1 1 1 HEAT repeats RIX1 PF08167.7 CEH12242.1 - 0.024 14.2 0.2 0.31 10.6 0.1 1.9 1 1 1 2 2 2 0 rRNA processing/ribosome biogenesis Peptidase_M9_N PF08453.5 CEH12242.1 - 0.025 13.9 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M9 N-terminal HEAT PF02985.17 CEH12242.1 - 0.049 13.7 0.1 0.16 12.1 0.1 1.9 1 0 0 1 1 1 0 HEAT repeat IBN_N PF03810.14 CEH12242.1 - 0.06 13.2 0.1 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Importin-beta N-terminal domain ACOX PF01756.14 CEH12244.1 - 1.8e-45 154.6 0.0 4.6e-45 153.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 CEH12244.1 - 4.4e-14 51.7 0.9 1.1e-13 50.4 0.6 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 CEH12244.1 - 3e-10 40.4 0.1 1.7e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 CEH12244.1 - 9.3e-05 22.5 2.5 0.00061 19.9 1.7 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Abhydrolase_2 PF02230.11 CEH12245.1 - 5.3e-15 55.4 0.0 6.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 CEH12245.1 - 2.7e-07 30.7 3.4 3.6e-07 30.2 2.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH12245.1 - 0.00074 19.2 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_11 PF13414.1 CEH12246.1 - 0.4 10.3 11.4 0.28 10.8 2.5 3.2 2 1 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 CEH12246.1 - 0.54 9.9 3.0 0.46 10.1 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-MIZ PF02891.15 CEH12247.1 - 2.2e-16 59.0 0.6 3.5e-16 58.4 0.4 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.1 CEH12247.1 - 1.3e-15 57.7 0.0 2.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.3 CEH12247.1 - 2e-07 30.4 0.1 3.4e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 CEH12247.1 - 1.8e-06 27.2 0.0 5.5e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 SAP domain Methyltransf_2 PF00891.13 CEH12248.1 - 7.1e-23 81.0 0.0 9.1e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 CEH12248.1 - 0.00022 20.9 0.0 0.00047 19.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TFIIF_alpha PF05793.7 CEH12249.1 - 0.41 8.9 4.9 0.53 8.5 3.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_M28 PF04389.12 CEH12251.1 - 6.8e-14 51.9 0.2 1.6e-13 50.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 CEH12251.1 - 6.7e-05 22.5 0.1 0.00018 21.1 0.1 1.7 1 0 0 1 1 1 1 PA domain Dynamin_M PF01031.15 CEH12252.1 - 1.4e-105 352.3 0.0 2.4e-105 351.5 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CEH12252.1 - 1.5e-54 184.3 0.0 3e-54 183.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CEH12252.1 - 2.7e-27 94.4 9.4 3.9e-27 93.9 4.5 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CEH12252.1 - 0.0036 17.2 1.4 0.044 13.7 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CEH12252.1 - 0.065 13.7 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein FSH1 PF03959.8 CEH12253.1 - 6.9e-47 159.6 0.0 1.1e-46 159.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 CEH12253.1 - 0.00044 20.2 0.0 0.04 13.7 0.0 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH12253.1 - 0.00052 19.7 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH12253.1 - 0.045 13.2 0.0 0.98 8.9 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 CEH12253.1 - 0.052 13.2 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal CDC45 PF02724.9 CEH12253.1 - 0.079 10.9 0.0 0.1 10.5 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_2 PF02230.11 CEH12253.1 - 0.1 12.0 0.2 1.2 8.4 0.1 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF1191 PF06697.7 CEH12254.1 - 0.018 13.8 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) UPF0016 PF01169.14 CEH12254.1 - 0.025 14.6 1.1 0.055 13.6 0.1 1.9 2 1 0 2 2 2 0 Uncharacterized protein family UPF0016 DUF1275 PF06912.6 CEH12254.1 - 0.033 13.3 0.2 0.037 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) MFS_1 PF07690.11 CEH12254.1 - 0.07 11.8 0.1 0.07 11.8 0.1 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Gpi16 PF04113.9 CEH12255.1 - 9.9e-54 182.3 0.1 1.3e-20 73.0 0.0 3.0 2 1 1 3 3 3 3 Gpi16 subunit, GPI transamidase component ACP_syn_III_C PF08541.5 CEH12256.1 - 0.0069 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal BOP1NT PF08145.7 CEH12256.1 - 0.014 15.1 0.1 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 BOP1NT (NUC169) domain Arch_ATPase PF01637.13 CEH12256.1 - 0.043 13.5 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase MFS_1 PF07690.11 CEH12259.1 - 3e-24 85.3 18.2 4e-24 84.9 12.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 CEH12259.1 - 0.026 14.5 1.0 0.11 12.5 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1228) FixP_N PF14715.1 CEH12259.1 - 0.13 11.6 1.0 2.6 7.5 0.1 2.8 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Peptidase_C97 PF05903.9 CEH12260.1 - 1.2e-31 109.5 0.0 1.8e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 CEH12260.1 - 1.7e-10 40.1 0.1 3.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 CEH12260.1 - 0.028 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Tox-PL-2 PF15643.1 CEH12260.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Papain fold toxin 2 Thioredoxin_2 PF13098.1 CEH12260.1 - 0.19 11.9 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Exo_endo_phos PF03372.18 CEH12261.1 - 1.2e-09 38.5 0.0 2.1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1640 PF07798.6 CEH12262.1 - 7.4e-12 45.6 5.0 2.9e-11 43.7 3.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) OmpH PF03938.9 CEH12262.1 - 0.037 13.9 3.8 0.12 12.2 0.4 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MTHFR PF02219.12 CEH12264.1 - 2.4e-84 282.8 0.0 9.9e-62 208.6 0.0 4.0 2 1 1 3 3 3 3 Methylenetetrahydrofolate reductase ESR1_C PF12743.2 CEH12266.1 - 0.065 12.7 0.4 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal TFCD_C PF12612.3 CEH12267.1 - 8.4e-27 93.8 4.0 8.6e-26 90.5 0.0 4.2 4 2 1 6 6 6 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.1 CEH12267.1 - 0.0012 19.2 17.5 1.8 9.1 0.0 7.8 6 1 1 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.1 CEH12267.1 - 0.0018 18.4 14.1 0.26 11.5 0.0 6.0 5 1 0 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.2 CEH12267.1 - 0.011 16.0 0.0 0.39 11.1 0.0 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CEH12267.1 - 0.014 15.4 0.0 0.014 15.4 0.0 8.8 10 0 0 10 10 10 0 HEAT repeat Arm PF00514.18 CEH12267.1 - 0.16 11.8 3.7 8.9 6.3 0.1 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 CEH12267.1 - 1.6 9.3 0.0 1.6 9.3 0.0 5.0 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Sugar_tr PF00083.19 CEH12268.1 - 3.7e-26 91.7 25.1 1.1e-18 67.1 8.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEH12268.1 - 3.8e-23 81.7 32.4 1.2e-16 60.3 12.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily INCENP_ARK-bind PF03941.10 CEH12269.1 - 0.0057 16.4 0.1 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Myb_DNA-binding PF00249.26 CEH12270.1 - 1e-12 47.8 10.4 0.0063 16.5 0.2 6.1 6 0 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH12270.1 - 2.9e-12 46.5 14.6 6e-06 26.2 0.1 5.7 3 1 4 7 7 7 4 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CEH12270.1 - 1.2e-05 25.2 12.4 0.29 11.2 0.0 5.7 6 0 0 6 6 6 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 CEH12270.1 - 9 6.5 9.6 23 5.2 0.1 4.6 4 1 1 5 5 5 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PhoD PF09423.5 CEH12271.1 - 1.2e-129 432.8 5.3 1.4e-129 432.5 3.6 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase NMT PF01233.14 CEH12273.1 - 3.2e-76 254.4 0.1 6.3e-76 253.4 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 CEH12273.1 - 1.2e-60 204.2 0.0 4.2e-60 202.4 0.0 1.9 2 1 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 CEH12273.1 - 0.00012 21.9 0.0 0.00044 20.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CEH12273.1 - 0.063 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.8 CEH12276.1 - 8e-18 64.7 0.3 3e-16 59.6 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CEH12276.1 - 1.1e-09 37.4 0.0 6.1e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 CEH12276.1 - 0.036 13.2 0.0 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Plectin PF00681.15 CEH12276.1 - 0.11 12.0 0.0 34 4.0 0.0 3.2 3 0 0 3 3 3 0 Plectin repeat tRNA-synt_2 PF00152.15 CEH12277.1 - 1.2e-46 159.1 0.2 7.2e-46 156.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 CEH12277.1 - 1e-05 24.5 0.1 1.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 CEH12277.1 - 4.2e-05 23.3 0.1 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Sec6 PF06046.8 CEH12277.1 - 0.095 10.7 0.8 0.19 9.7 0.6 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec6 Metallothio_5 PF02067.10 CEH12278.1 - 0.04 13.9 5.8 0.079 13.0 4.0 1.4 1 0 0 1 1 1 0 Metallothionein family 5 TPP_enzyme_N PF02776.13 CEH12280.1 - 5e-23 81.4 0.2 1.9e-12 47.0 0.0 2.9 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CEH12280.1 - 7.4e-22 77.5 0.0 1.4e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CEH12280.1 - 9.3e-12 44.7 0.0 2.5e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Aldo_ket_red PF00248.16 CEH12281.1 - 7.8e-51 172.5 0.0 9.9e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADC PF06314.6 CEH12282.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Xan_ur_permease PF00860.15 CEH12283.1 - 4.1e-15 55.1 21.1 1.8e-14 53.0 11.5 3.2 1 1 1 2 2 2 1 Permease family FUSC-like PF12805.2 CEH12283.1 - 1.2 8.0 4.1 2.4 7.0 2.8 1.5 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Rav1p_C PF12234.3 CEH12285.1 - 8.6e-126 420.6 0.0 1.2e-125 420.1 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 CEH12285.1 - 2.5 8.1 7.7 0.84 9.6 0.1 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat GFA PF04828.9 CEH12286.1 - 4.8e-23 80.9 0.6 8.3e-23 80.1 0.4 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 CEH12286.1 - 0.00068 19.3 0.1 0.0041 16.8 0.1 2.1 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NOB1_Zn_bind PF08772.6 CEH12286.1 - 0.071 12.9 3.8 0.41 10.5 0.1 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Rpr2 PF04032.11 CEH12286.1 - 0.42 10.5 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Kinesin PF00225.18 CEH12287.1 - 3.1e-61 206.9 0.0 3.9e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain AAA_24 PF13479.1 CEH12287.1 - 0.068 12.7 0.0 1.9 8.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain PMT_C PF11647.3 CEH12289.1 - 0.095 12.3 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 NEL PF14496.1 CEH12291.1 - 1.5e-31 109.4 3.7 1.7e-31 109.2 2.5 1.0 1 0 0 1 1 1 1 C-terminal novel E3 ligase, LRR-interacting HTH_Tnp_Tc3_1 PF11427.3 CEH12291.1 - 0.092 12.3 0.2 0.42 10.2 0.1 2.0 2 0 0 2 2 2 0 Tc3 transposase GABP-alpha PF11620.3 CEH12293.1 - 0.11 12.4 0.1 1.2 9.1 0.0 2.4 2 1 1 3 3 3 0 GA-binding protein alpha chain CN_hydrolase PF00795.17 CEH12294.1 - 8.4e-30 103.5 0.1 1.1e-29 103.1 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Chromate_transp PF02417.10 CEH12295.1 - 5.6e-55 185.5 30.0 4.9e-28 97.8 6.6 2.8 2 1 0 2 2 2 2 Chromate transporter Ferric_reduct PF01794.14 CEH12295.1 - 3.8 7.6 9.4 0.054 13.5 0.5 2.3 3 1 0 3 3 3 0 Ferric reductase like transmembrane component NicO PF03824.11 CEH12296.1 - 0.13 11.5 0.3 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Zip PF02535.17 CEH12296.1 - 0.16 10.9 5.4 0.18 10.8 3.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PDGF_N PF04692.8 CEH12296.1 - 0.23 11.9 1.4 0.36 11.3 1.0 1.3 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region SelP_N PF04592.9 CEH12296.1 - 3.3 7.0 10.9 4.1 6.7 7.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region F_actin_cap_B PF01115.12 CEH12301.1 - 3e-75 252.5 0.0 4.1e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit RhoGEF PF00621.15 CEH12302.1 - 3e-35 121.7 0.0 6.2e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF2093 PF09866.4 CEH12302.1 - 0.045 12.9 0.0 0.15 11.2 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) Syntaxin-6_N PF09177.6 CEH12302.1 - 1.1 9.7 5.4 1.6 9.1 0.1 3.5 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.8 CEH12302.1 - 9.4 5.5 7.0 2.1 7.7 0.4 2.8 2 1 1 3 3 3 0 fzo-like conserved region WD40 PF00400.27 CEH12303.1 - 1.1e-20 72.6 5.8 4.1e-09 35.9 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase PF00069.20 CEH12303.1 - 1.7e-17 63.4 0.0 3.9e-17 62.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 CEH12303.1 - 1.7e-09 36.9 8.2 0.012 15.5 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat Pkinase_Tyr PF07714.12 CEH12303.1 - 2.3e-06 26.9 0.1 0.01 14.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_2 PF13646.1 CEH12303.1 - 3.3e-05 24.0 4.7 0.024 14.8 0.3 4.3 4 1 1 5 5 5 2 HEAT repeats Kinase-like PF14531.1 CEH12303.1 - 0.0068 15.3 0.0 0.041 12.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RasGEF_N_2 PF14663.1 CEH12303.1 - 0.11 12.4 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pox_TAP PF03355.9 CEH12303.1 - 0.22 10.8 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Viral Trans-Activator Protein CPSF_A PF03178.10 CEH12303.1 - 0.23 10.5 0.0 0.39 9.7 0.0 1.2 1 0 0 1 1 1 0 CPSF A subunit region Ribosomal_S2 PF00318.15 CEH12304.1 - 2.3e-44 151.1 0.0 4.5e-41 140.4 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 RRM_1 PF00076.17 CEH12305.1 - 5.9e-17 61.0 0.0 9.9e-17 60.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH12305.1 - 4.5e-09 36.1 0.0 8e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH12305.1 - 0.00086 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CITED PF04487.7 CEH12307.1 - 0.061 13.5 0.4 0.066 13.4 0.3 1.1 1 0 0 1 1 1 0 CITED MBOAT PF03062.14 CEH12308.1 - 4.6e-46 157.4 20.2 4.6e-46 157.4 14.0 1.7 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family ESSS PF10183.4 CEH12308.1 - 0.013 15.8 0.1 0.039 14.3 0.0 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GHMP_kinases_N PF00288.21 CEH12309.1 - 2.9e-13 49.6 0.1 2.9e-13 49.6 0.1 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CEH12309.1 - 0.00047 20.2 0.6 0.0031 17.6 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal Atg14 PF10186.4 CEH12310.1 - 5.7e-18 64.8 2.8 1e-17 64.0 1.9 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 CEH12310.1 - 0.13 11.2 2.2 11 4.9 0.0 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 SHS2_Rpb7-N PF03876.12 CEH12311.1 - 1.9e-05 24.7 0.0 3.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 APG6 PF04111.7 CEH12312.1 - 0.56 9.2 9.7 1 8.3 6.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Vac14_Fig4_bd PF11916.3 CEH12313.1 - 1.5e-80 268.6 9.3 6.7e-80 266.5 4.0 2.5 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CEH12313.1 - 2.4e-46 156.0 0.0 1.5e-41 140.6 0.0 4.7 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CEH12313.1 - 1.5e-15 55.8 6.9 2.7e-05 23.8 0.0 7.4 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 CEH12313.1 - 7.5e-09 35.7 6.8 0.017 15.3 0.0 5.8 4 2 1 5 5 5 4 HEAT repeats CLASP_N PF12348.3 CEH12313.1 - 5e-06 26.0 0.2 0.62 9.3 0.0 4.4 4 1 1 5 5 5 2 CLASP N terminal HEAT_EZ PF13513.1 CEH12313.1 - 5.6e-05 23.4 5.3 0.15 12.5 0.0 6.9 6 2 2 8 8 8 1 HEAT-like repeat Cnd1 PF12717.2 CEH12313.1 - 0.0077 16.0 2.1 1.4 8.7 0.0 3.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 CEH12313.1 - 0.0078 16.1 0.5 3.1 7.6 0.0 3.6 4 0 0 4 4 4 1 Parkin co-regulated protein MIP PF00230.15 CEH12314.1 - 2.4e-06 27.1 9.3 3.7e-06 26.5 6.5 1.3 1 0 0 1 1 1 1 Major intrinsic protein Dor1 PF04124.7 CEH12314.1 - 0.23 9.9 0.7 0.34 9.3 0.5 1.1 1 0 0 1 1 1 0 Dor1-like family V_ATPase_I PF01496.14 CEH12314.1 - 3.3 5.4 2.4 2.7 5.7 0.2 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family AAA PF00004.24 CEH12317.1 - 6.9e-13 48.9 0.0 1.4e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEH12317.1 - 6.2e-11 42.6 0.0 3.1e-10 40.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CEH12317.1 - 3.3e-06 27.2 0.0 9.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH12317.1 - 0.00013 21.6 1.1 0.00048 19.8 0.2 2.3 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 CEH12317.1 - 0.049 13.3 0.0 0.28 10.8 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 CEH12317.1 - 0.051 13.8 0.1 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CEH12317.1 - 0.068 13.9 0.2 0.48 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain PIF1 PF05970.9 CEH12317.1 - 0.071 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase NACHT PF05729.7 CEH12317.1 - 0.081 12.5 0.0 0.41 10.2 0.0 2.1 1 1 0 1 1 1 0 NACHT domain Zot PF05707.7 CEH12317.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PPP4R2 PF09184.6 CEH12317.1 - 7 6.0 9.1 12 5.2 6.3 1.3 1 0 0 1 1 1 0 PPP4R2 ORMDL PF04061.9 CEH12318.1 - 3.8e-55 185.1 2.9 4.9e-55 184.8 2.0 1.1 1 0 0 1 1 1 1 ORMDL family GTP_EFTU PF00009.22 CEH12320.1 - 6.6e-49 165.8 0.0 1.2e-48 165.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CEH12320.1 - 1.6e-09 37.5 0.0 3.1e-07 30.1 0.0 2.5 1 1 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 CEH12320.1 - 1.5e-08 34.3 0.0 3.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CEH12320.1 - 8.6e-07 28.9 0.0 2.3e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEH12320.1 - 0.0048 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.13 CEH12320.1 - 0.018 14.6 0.0 0.066 12.7 0.0 2.0 1 1 0 1 1 1 0 Elongation factor G, domain IV FATC PF02260.15 CEH12321.1 - 0.41 10.1 3.1 0.94 8.9 2.2 1.6 1 0 0 1 1 1 0 FATC domain Peptidase_C14 PF00656.17 CEH12322.1 - 5.3e-62 209.7 0.0 6.5e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain ThiC-associated PF13667.1 CEH12322.1 - 0.039 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain DHFR_1 PF00186.14 CEH12323.1 - 3.8e-23 81.8 0.0 2.1e-11 43.6 0.0 3.3 2 1 1 3 3 3 3 Dihydrofolate reductase DUF1227 PF06777.6 CEH12324.1 - 7.9e-54 181.3 0.3 7.9e-54 181.3 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 CEH12324.1 - 8.4e-47 159.2 0.1 2.3e-46 157.8 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 CEH12324.1 - 1.6e-44 151.3 0.0 3.4e-43 147.0 0.0 2.3 1 1 0 1 1 1 1 DEAD_2 SNF2_N PF00176.18 CEH12324.1 - 0.00098 18.0 0.0 0.003 16.3 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 CEH12324.1 - 0.016 14.7 0.1 5.6 6.4 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.10 CEH12324.1 - 0.017 14.9 2.3 0.2 11.4 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CEH12324.1 - 0.066 13.3 0.1 6.2 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CEH12324.1 - 0.11 11.7 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein PhnJ PF06007.6 CEH12326.1 - 0.022 13.5 0.1 0.038 12.7 0.1 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ IMS PF00817.15 CEH12327.1 - 1.5e-27 96.1 0.0 3.3e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CEH12327.1 - 1.3e-05 25.1 0.0 0.0002 21.3 0.0 2.5 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 CEH12327.1 - 0.015 15.2 1.9 0.038 13.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4414) 14-3-3 PF00244.15 CEH12328.1 - 2.7e-117 389.9 5.4 3.6e-117 389.5 3.8 1.2 1 0 0 1 1 1 1 14-3-3 protein WD40 PF00400.27 CEH12328.1 - 2.2e-08 33.6 8.5 0.00065 19.4 0.9 5.2 4 1 0 4 4 4 2 WD domain, G-beta repeat SPACA7 PF15307.1 CEH12328.1 - 0.061 13.4 0.7 0.39 10.8 0.5 2.3 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 Apc4_WD40 PF12894.2 CEH12328.1 - 0.15 11.6 0.0 0.54 9.8 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_E PF04733.9 CEH12329.1 - 6.4e-42 143.7 0.0 7.6e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 CEH12329.1 - 0.04 14.2 13.0 0.05 13.9 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CEH12329.1 - 0.091 13.4 14.7 0.26 12.0 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEH12329.1 - 0.12 12.0 1.1 0.97 9.1 0.0 2.9 3 1 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 CEH12329.1 - 1.1 9.4 6.9 1.7 8.7 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Clathrin_lg_ch PF01086.12 CEH12330.1 - 2.5e-39 135.5 14.2 6.8e-37 127.5 6.7 2.3 1 1 1 2 2 2 2 Clathrin light chain NMDAR2_C PF10565.4 CEH12330.1 - 0.024 13.3 1.3 0.028 13.1 0.9 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus DUF4407 PF14362.1 CEH12330.1 - 0.51 9.2 5.5 0.89 8.4 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DEC-1_C PF04626.8 CEH12330.1 - 1.1 9.4 4.6 1.3 9.1 2.1 1.9 1 1 0 1 1 1 0 Dec-1 protein, C terminal region DUF4337 PF14235.1 CEH12330.1 - 1.3 8.8 6.6 2.2 8.0 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3128 PF11326.3 CEH12332.1 - 6e-21 74.3 1.1 1e-20 73.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Ndufs5 PF10200.4 CEH12332.1 - 0.039 13.9 0.3 0.069 13.1 0.2 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Methyltransf_16 PF10294.4 CEH12333.1 - 1.7e-15 56.9 0.0 7.7e-15 54.7 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CEH12333.1 - 8.3e-07 29.5 0.0 1.4e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH12333.1 - 0.019 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CEH12333.1 - 0.028 13.8 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 CEH12333.1 - 0.081 13.4 0.0 0.26 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain TOM13 PF08219.6 CEH12334.1 - 4.7e-09 35.8 0.4 1.2e-08 34.6 0.3 1.6 1 0 0 1 1 1 1 Outer membrane protein TOM13 RRM_1 PF00076.17 CEH12336.1 - 1.8e-15 56.3 0.0 2.5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH12336.1 - 9.7e-12 44.6 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH12336.1 - 4.5e-09 36.0 0.0 6.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARF7EP_C PF14949.1 CEH12339.1 - 3.3 8.1 5.7 1 9.7 1.1 2.1 2 0 0 2 2 2 0 ARF7 effector protein C-terminus He_PIG PF05345.7 CEH12340.1 - 6.2e-07 29.3 12.7 0.02 14.9 0.3 5.4 5 1 1 6 6 6 3 Putative Ig domain BACON PF13004.2 CEH12340.1 - 0.043 14.0 1.1 0.43 10.8 0.0 3.0 3 0 0 3 3 3 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal CMAS PF02353.15 CEH12341.1 - 1.6e-29 102.8 0.7 2.3e-29 102.3 0.5 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 CEH12341.1 - 3.1e-12 46.3 0.0 1.6e-11 44.0 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH12341.1 - 5.8e-12 45.9 0.0 1.5e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEH12341.1 - 1.7e-09 37.2 0.0 3.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CEH12341.1 - 4.6e-08 33.6 0.0 1.4e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH12341.1 - 7.3e-08 32.8 0.0 2.2e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH12341.1 - 3.8e-07 29.9 0.1 1.1e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH12341.1 - 5.4e-05 23.4 0.0 0.00015 22.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEH12341.1 - 0.00052 19.1 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 CEH12341.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 CEH12341.1 - 0.0021 18.0 0.0 0.0056 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CEH12341.1 - 0.0042 16.2 0.0 0.0083 15.3 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 CEH12341.1 - 0.0051 16.3 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.10 CEH12341.1 - 0.01 14.9 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.13 CEH12341.1 - 0.032 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DOT1 PF08123.8 CEH12341.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF938 PF06080.7 CEH12341.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Adap_comp_sub PF00928.16 CEH12342.1 - 8.1e-92 307.0 0.0 1.1e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CEH12342.1 - 1.4e-06 28.0 0.2 2.5e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Iso_dh PF00180.15 CEH12343.1 - 9e-119 396.4 0.0 1e-118 396.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase 4HBT_3 PF13622.1 CEH12345.1 - 8.3e-15 55.2 0.1 1.3e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily PP2C PF00481.16 CEH12346.1 - 5.2e-26 91.5 0.0 2.6e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Cyt-b5 PF00173.23 CEH12346.1 - 1.2e-22 79.5 0.0 3.8e-22 77.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain SNF2_N PF00176.18 CEH12347.1 - 3.4e-63 213.2 0.0 5.6e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEH12347.1 - 7e-14 51.4 0.0 1.8e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain cwf18 PF08315.7 CEH12348.1 - 5.1e-28 98.1 9.3 7e-28 97.6 6.5 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Sigma70_r2 PF04542.9 CEH12348.1 - 0.0079 15.7 0.0 0.023 14.2 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 DUF3166 PF11365.3 CEH12348.1 - 0.12 12.8 0.2 0.12 12.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) Zn_clus PF00172.13 CEH12349.1 - 1e-06 28.5 8.1 1.7e-06 27.8 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TetR_C_9 PF14514.1 CEH12349.1 - 0.073 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, TetR, C-terminal Glyoxalase_2 PF12681.2 CEH12350.1 - 3.2e-06 27.7 0.0 7.7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase-like domain Cauli_VI PF01693.11 CEH12350.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Abhydrolase_5 PF12695.2 CEH12351.1 - 0.001 18.8 0.3 0.0046 16.7 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH12351.1 - 0.01 15.7 2.2 0.041 13.7 0.0 2.5 1 1 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CEH12351.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein SH3_9 PF14604.1 CEH12352.1 - 7.6e-14 51.0 0.1 1.5e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 CEH12352.1 - 6.7e-13 48.7 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 CEH12352.1 - 1.1e-12 47.0 0.3 2.5e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEH12352.1 - 1.3e-09 37.4 0.0 3e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 CEH12352.1 - 4.4e-08 32.8 0.0 8.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CEH12352.1 - 2.3e-05 24.4 0.1 4.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 CEH12352.1 - 0.058 13.4 0.2 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PH_11 PF15413.1 CEH12352.1 - 0.076 13.2 0.1 0.21 11.8 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Ssu72 PF04722.8 CEH12353.1 - 1.2e-81 272.7 0.0 1.4e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Pirin PF02678.11 CEH12353.1 - 0.036 13.9 0.1 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Pirin LMWPc PF01451.16 CEH12353.1 - 0.15 12.4 0.7 0.34 11.2 0.3 1.7 1 1 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Nucleoporin_FG PF13634.1 CEH12354.1 - 5.5e-08 33.0 94.1 0.00018 21.7 30.6 2.2 1 1 1 2 2 2 2 Nucleoporin FG repeat region Snf7 PF03357.16 CEH12357.1 - 2.7e-23 82.1 12.9 3.5e-23 81.8 9.0 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 CEH12357.1 - 0.00033 20.1 2.2 0.00049 19.5 1.6 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway GrpE PF01025.14 CEH12357.1 - 1 8.8 6.2 1.2 8.6 3.3 1.8 1 1 0 1 1 1 0 GrpE T2SM PF04612.7 CEH12357.1 - 1.6 8.5 7.0 0.26 11.0 0.2 2.4 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein M CDC37_N PF03234.9 CEH12357.1 - 9.9 6.4 9.9 0.71 10.1 1.5 2.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF3591 PF12157.3 CEH12358.1 - 4.2e-176 585.8 1.8 7.1e-176 585.0 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 CEH12358.1 - 7.2e-06 25.5 0.7 1.7e-05 24.4 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Usp PF00582.21 CEH12358.1 - 0.56 10.3 4.7 3.4 7.8 3.3 2.4 1 0 0 1 1 1 0 Universal stress protein family Med16 PF11635.3 CEH12358.1 - 0.57 8.0 0.2 0.86 7.4 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 16 UAA PF08449.6 CEH12359.1 - 1.4e-65 221.1 3.9 2.1e-64 217.3 2.7 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 CEH12359.1 - 1.4e-08 34.5 11.7 1.1e-06 28.3 2.7 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CEH12359.1 - 4.1e-06 26.8 22.7 1.2e-05 25.3 5.2 4.2 4 1 0 4 4 4 2 EamA-like transporter family DUF914 PF06027.7 CEH12359.1 - 0.00016 20.6 0.2 0.0012 17.7 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 CEH12359.1 - 0.00065 19.8 7.4 0.0047 17.1 0.4 2.9 3 0 0 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CEH12359.1 - 0.00099 18.2 0.4 0.19 10.8 0.0 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter Vps5 PF09325.5 CEH12360.1 - 1e-07 31.4 6.4 1.6e-07 30.8 4.4 1.2 1 0 0 1 1 1 1 Vps5 C terminal like Dynactin_p62 PF05502.8 CEH12361.1 - 3.8e-78 263.3 0.0 5.1e-47 160.7 2.3 2.4 2 1 1 3 3 3 2 Dynactin p62 family CTNNBL PF08216.6 CEH12362.1 - 5.9e-24 83.7 0.8 1.5e-23 82.4 0.6 1.7 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear RasGAP PF00616.14 CEH12363.1 - 2.2e-32 112.3 0.0 5e-32 111.1 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 CEH12363.1 - 1.6e-11 44.3 0.0 9.2e-11 41.8 0.0 2.4 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CEH12363.1 - 0.059 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 CRAL/TRIO domain DUF3632 PF12311.3 CEH12363.1 - 0.076 12.8 0.1 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) GrpE PF01025.14 CEH12363.1 - 0.47 9.9 0.1 1.1 8.7 0.0 1.5 1 0 0 1 1 1 0 GrpE Beta-lactamase PF00144.19 CEH12364.1 - 7.8e-28 97.4 0.2 1.7e-27 96.2 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase RF-1 PF00472.15 CEH12368.1 - 3.2e-17 62.3 0.3 4.5e-17 61.8 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain Glyco_hydro_9 PF00759.14 CEH12368.1 - 0.099 11.5 0.2 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 HALZ PF02183.13 CEH12369.1 - 0.079 12.6 12.2 18 5.1 0.1 5.0 3 1 1 4 4 4 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 CEH12369.1 - 0.14 11.8 0.2 0.62 9.8 0.1 2.1 1 0 0 1 1 1 0 Sperm tail C-terminal domain Bap31 PF05529.7 CEH12369.1 - 2 7.8 4.8 29 4.0 0.0 2.7 1 1 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF972 PF06156.8 CEH12369.1 - 2.5 8.4 15.2 30 5.0 0.0 4.6 3 2 2 5 5 5 0 Protein of unknown function (DUF972) HAP1_N PF04849.8 CEH12369.1 - 3.7 6.4 19.8 2.8 6.7 0.3 2.9 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Coatomer_WDAD PF04053.9 CEH12370.1 - 1.1e-152 508.9 0.0 3.5e-151 503.9 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 CEH12370.1 - 4.1e-48 159.6 12.8 8.6e-11 41.2 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CEH12370.1 - 0.011 15.5 0.0 13 5.5 0.0 4.1 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 CEH12370.1 - 0.015 13.4 0.1 0.1 10.7 0.0 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.1 CEH12370.1 - 0.044 12.8 0.3 0.43 9.6 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DUF2051 PF09738.4 CEH12371.1 - 0.27 10.4 2.5 0.17 11.1 0.6 1.6 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) Methyltransf_23 PF13489.1 CEH12372.1 - 1.8e-11 44.0 0.0 4.4e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH12372.1 - 1.6e-08 34.8 0.0 3.8e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH12372.1 - 9e-08 32.4 0.0 2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH12372.1 - 2.1e-05 24.9 0.0 4.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH12372.1 - 6.4e-05 23.5 0.0 0.00018 22.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH12372.1 - 7.2e-05 22.8 0.0 0.00023 21.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH12372.1 - 0.00032 20.3 0.0 0.00096 18.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEH12372.1 - 0.00082 18.5 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CEH12372.1 - 0.029 13.7 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 CEH12372.1 - 0.03 14.3 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase OGG_N PF07934.7 CEH12373.1 - 1.2e-23 83.3 0.2 7.1e-20 71.1 0.2 2.3 2 0 0 2 2 2 2 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CEH12373.1 - 3.3e-07 30.5 0.0 7.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CEH12373.1 - 0.15 11.7 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif ABC_tran PF00005.22 CEH12375.1 - 6.1e-47 159.3 0.0 1.6e-22 80.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 CEH12375.1 - 5.1e-21 74.2 0.7 5.1e-21 74.2 0.5 2.8 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 CEH12375.1 - 2.3e-17 63.8 5.6 0.0025 17.8 0.0 4.7 3 1 2 5 5 5 4 AAA domain AAA_23 PF13476.1 CEH12375.1 - 5.6e-10 39.8 7.1 0.00028 21.3 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 CEH12375.1 - 3.2e-09 36.1 0.2 0.00092 18.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CEH12375.1 - 8.3e-09 34.9 1.1 0.49 9.5 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CEH12375.1 - 1.8e-07 32.0 0.1 0.045 14.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 CEH12375.1 - 2.5e-06 27.9 0.0 0.086 13.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 CEH12375.1 - 3.7e-06 26.2 0.1 0.002 17.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CEH12375.1 - 4.3e-06 26.6 0.0 0.007 16.3 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 CEH12375.1 - 5.6e-06 26.1 0.0 0.1 12.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 CEH12375.1 - 2.9e-05 24.1 0.2 0.23 11.4 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 CEH12375.1 - 5e-05 22.7 0.1 0.14 11.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CEH12375.1 - 5.2e-05 23.5 1.8 0.31 11.3 0.0 3.0 3 1 0 3 3 2 2 AAA domain Dynamin_N PF00350.18 CEH12375.1 - 5.8e-05 22.9 5.0 0.22 11.3 0.0 3.8 2 1 1 3 3 3 2 Dynamin family AAA_15 PF13175.1 CEH12375.1 - 6.2e-05 22.2 9.8 0.19 10.7 0.0 4.5 4 1 1 5 5 5 2 AAA ATPase domain MobB PF03205.9 CEH12375.1 - 6.6e-05 22.6 0.7 0.55 9.9 0.1 3.2 2 1 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CEH12375.1 - 7.2e-05 22.9 3.8 0.057 13.5 0.0 3.5 3 3 1 4 4 2 2 AAA domain AAA_28 PF13521.1 CEH12375.1 - 7.7e-05 22.7 0.0 0.41 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CEH12375.1 - 0.00015 21.3 0.1 0.25 10.7 0.1 3.2 3 0 0 3 3 3 1 AAA-like domain AAA PF00004.24 CEH12375.1 - 0.00015 21.9 0.1 2.1 8.5 0.1 3.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 CEH12375.1 - 0.00041 19.8 0.2 1 8.7 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_5 PF07728.9 CEH12375.1 - 0.00073 19.2 0.6 0.35 10.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 CEH12375.1 - 0.00091 19.0 0.0 0.64 9.9 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CEH12375.1 - 0.0012 18.9 1.6 0.59 10.3 0.0 3.2 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.1 CEH12375.1 - 0.002 18.0 0.2 0.74 9.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain FeoB_N PF02421.13 CEH12375.1 - 0.0027 16.9 0.1 0.13 11.5 0.1 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_14 PF13173.1 CEH12375.1 - 0.0032 17.3 0.0 12 5.8 0.0 4.3 5 0 0 5 5 4 0 AAA domain cobW PF02492.14 CEH12375.1 - 0.0033 16.9 0.3 0.92 8.9 0.0 2.9 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 CEH12375.1 - 0.0039 16.7 0.5 0.57 9.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 CEH12375.1 - 0.004 16.8 0.0 0.44 10.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Septin PF00735.13 CEH12375.1 - 0.0049 15.9 0.0 2.1 7.2 0.0 2.5 2 0 0 2 2 2 1 Septin AAA_30 PF13604.1 CEH12375.1 - 0.01 15.4 5.0 0.16 11.5 0.1 3.2 3 1 0 3 3 3 0 AAA domain T2SE PF00437.15 CEH12375.1 - 0.012 14.5 0.1 2.5 6.9 0.0 2.5 2 1 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 CEH12375.1 - 0.019 14.4 1.0 6.1 6.3 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 CEH12375.1 - 0.027 13.3 0.0 5.3 5.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.12 CEH12375.1 - 0.027 14.2 6.2 2.9 7.6 0.0 4.1 4 1 1 5 5 4 0 Domain of unknown function DUF87 DivIC PF04977.10 CEH12375.1 - 0.034 13.6 7.3 1.8 8.0 1.0 2.7 2 0 0 2 2 2 0 Septum formation initiator ATP-synt_ab PF00006.20 CEH12375.1 - 0.041 13.3 1.4 8.5 5.8 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DAP3 PF10236.4 CEH12375.1 - 0.042 12.7 0.7 2.3 7.0 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.10 CEH12375.1 - 0.067 12.9 5.4 2.9 7.5 0.1 4.1 5 0 0 5 5 5 0 NTPase Pox_A32 PF04665.7 CEH12375.1 - 0.85 8.8 5.4 3.1 7.0 0.0 3.1 4 0 0 4 4 4 0 Poxvirus A32 protein AAA_13 PF13166.1 CEH12375.1 - 1.8 6.9 11.3 1.1 7.6 0.0 3.9 5 0 0 5 5 5 0 AAA domain SelR PF01641.13 CEH12376.1 - 3.7e-48 162.2 0.1 4.8e-48 161.9 0.1 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 CEH12376.1 - 0.43 10.4 3.0 4.5 7.1 2.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon ECH PF00378.15 CEH12377.1 - 3.7e-49 167.0 0.0 4.4e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CBFD_NFYB_HMF PF00808.18 CEH12378.1 - 1.7e-22 79.2 0.8 2.4e-22 78.7 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEH12378.1 - 0.00062 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 CEH12378.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit HalX PF08663.5 CEH12378.1 - 0.046 13.6 2.0 0.13 12.2 1.4 1.8 1 0 0 1 1 1 0 HalX domain DUF3069 PF11269.3 CEH12378.1 - 0.22 11.6 1.5 0.37 10.8 0.3 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3069) RhoGEF PF00621.15 CEH12380.1 - 1.2e-22 80.6 0.0 5e-22 78.6 0.0 1.9 1 1 0 1 1 1 1 RhoGEF domain DUF732 PF05305.9 CEH12382.1 - 0.02 14.9 1.2 0.025 14.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF732) DUF3844 PF12955.2 CEH12382.1 - 0.077 13.1 1.1 0.11 12.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) Cofilin_ADF PF00241.15 CEH12383.1 - 4.3e-11 42.7 0.0 4.7e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MAP65_ASE1 PF03999.7 CEH12384.1 - 0.047 12.3 0.0 0.054 12.0 0.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF2052 PF09747.4 CEH12384.1 - 0.51 10.2 9.8 2.8 7.8 6.8 1.9 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) zf-RING_2 PF13639.1 CEH12386.1 - 3.3e-15 55.6 1.3 5.8e-15 54.8 0.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEH12386.1 - 4.3e-09 36.2 1.6 7.4e-09 35.4 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH12386.1 - 5.6e-08 32.3 0.3 1e-07 31.5 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain PA PF02225.17 CEH12386.1 - 1.2e-07 31.3 0.1 1.3e-06 28.0 0.0 2.7 1 1 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 CEH12386.1 - 9.9e-07 28.7 1.1 2e-06 27.8 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CEH12386.1 - 8.1e-06 25.4 2.3 1.4e-05 24.6 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH12386.1 - 9.9e-06 25.1 0.3 1.7e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEH12386.1 - 0.011 15.4 2.3 0.043 13.5 0.0 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 CEH12386.1 - 0.039 13.4 1.2 0.081 12.4 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 CEH12386.1 - 0.073 12.9 1.1 0.16 11.8 0.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CEH12386.1 - 0.17 11.8 1.9 0.77 9.7 1.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain DUF1180 PF06679.7 CEH12386.1 - 2.5 7.9 0.0 2.5 7.9 0.0 3.9 4 1 0 4 4 3 0 Protein of unknown function (DUF1180) DUF202 PF02656.10 CEH12388.1 - 3.8e-12 46.2 4.8 3.8e-12 46.2 3.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LHC PF00556.15 CEH12388.1 - 0.07 12.9 0.3 0.07 12.9 0.2 2.4 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF2615 PF11027.3 CEH12388.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Ribosomal_S17 PF00366.15 CEH12389.1 - 5.5e-28 96.8 1.6 7.6e-28 96.3 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L7Ae PF01248.21 CEH12390.1 - 2e-28 97.7 1.3 2.6e-28 97.3 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2042 PF09743.4 CEH12390.1 - 0.078 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) Chitin_synth_2 PF03142.10 CEH12391.1 - 9.1e-245 813.0 0.0 1.2e-244 812.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CEH12391.1 - 5.6e-101 338.6 0.0 1.1e-100 337.7 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Cornichon PF03311.9 CEH12391.1 - 8.7e-50 168.1 9.9 8.7e-50 168.1 6.9 2.9 2 1 0 2 2 2 1 Cornichon protein Cyt-b5 PF00173.23 CEH12391.1 - 1.7e-16 59.7 1.2 4.2e-08 32.8 0.0 3.2 4 0 0 4 4 4 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 CEH12391.1 - 9.7e-16 58.2 0.1 2.8e-12 46.9 0.0 3.6 4 0 0 4 4 4 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CEH12391.1 - 3.5e-15 56.2 5.1 3.5e-15 56.2 3.6 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CEH12391.1 - 2e-08 34.0 0.0 5.3e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEH12391.1 - 0.00015 21.0 0.0 0.00038 19.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Jiv90 PF14901.1 CEH12391.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Mito_carr PF00153.22 CEH12392.1 - 1.6e-57 191.2 0.4 5.7e-19 67.6 0.3 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.1 CEH12394.1 - 9.3e-07 28.7 0.0 2.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.15 CEH12394.1 - 0.03 14.3 0.0 0.1 12.6 0.0 2.0 1 0 0 1 1 1 0 PPR repeat PPR_3 PF13812.1 CEH12394.1 - 0.054 13.8 0.0 0.18 12.1 0.0 2.0 1 0 0 1 1 1 0 Pentatricopeptide repeat domain ELYS PF13934.1 CEH12395.1 - 1.9e-13 50.6 0.0 3.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex assembly Ras PF00071.17 CEH12396.1 - 3.3e-49 166.3 0.0 3.9e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH12396.1 - 6.3e-15 55.7 0.0 9.8e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH12396.1 - 1.4e-09 37.4 0.0 1.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEH12396.1 - 0.00036 19.7 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CEH12396.1 - 0.0043 15.7 0.8 1 7.9 0.0 2.5 2 1 1 3 3 3 2 G-protein alpha subunit Pox_A32 PF04665.7 CEH12396.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.17 CEH12396.1 - 0.031 14.4 0.1 0.29 11.3 0.0 2.1 1 1 0 1 1 1 0 RNA helicase STAS PF01740.16 CEH12396.1 - 0.08 12.3 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 STAS domain AAA_22 PF13401.1 CEH12396.1 - 0.089 12.9 0.2 0.26 11.4 0.1 1.7 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CEH12396.1 - 0.097 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.17 CEH12398.1 - 2.8e-28 97.3 0.0 3.3e-16 58.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH12398.1 - 3.1e-19 68.6 0.0 2.5e-10 40.1 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH12398.1 - 7.2e-15 54.5 0.0 4.9e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEH12398.1 - 1.7e-05 24.6 0.0 4.5e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 CEH12398.1 - 0.0025 17.5 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CEH12398.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 zf-CCCH PF00642.19 CEH12400.1 - 0.00038 20.0 1.2 0.00067 19.2 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UPF0258 PF06789.7 CEH12400.1 - 0.053 13.5 0.1 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) zf-CCCH_2 PF14608.1 CEH12400.1 - 0.67 10.0 2.4 1.5 8.9 1.6 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type ABC_tran PF00005.22 CEH12401.1 - 2.1e-61 206.1 0.0 4.3e-32 111.2 0.0 3.7 3 1 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 CEH12401.1 - 4.3e-45 154.2 17.5 9.9e-23 80.9 4.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CEH12401.1 - 5.3e-18 65.0 0.6 1.5e-09 37.3 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 CEH12401.1 - 8.1e-12 44.4 1.4 0.00033 19.3 0.0 4.4 4 1 0 4 4 4 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 CEH12401.1 - 3.1e-10 40.5 0.0 0.18 11.7 0.0 4.2 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 CEH12401.1 - 3.1e-10 39.4 1.4 0.00038 19.9 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CEH12401.1 - 1.6e-09 38.6 0.0 0.0037 18.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CEH12401.1 - 7.8e-09 34.9 0.0 0.0036 16.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CEH12401.1 - 1.2e-08 34.5 0.3 0.023 14.1 0.0 4.2 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.1 CEH12401.1 - 7.2e-07 29.4 0.3 0.1 12.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 CEH12401.1 - 1.1e-06 28.6 0.1 0.058 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CEH12401.1 - 1.1e-06 28.9 0.0 0.0087 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CEH12401.1 - 2.5e-06 27.6 4.2 0.0095 15.9 0.2 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 CEH12401.1 - 3e-05 24.4 0.2 0.26 11.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CEH12401.1 - 4.7e-05 22.9 1.0 0.59 9.5 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain MobB PF03205.9 CEH12401.1 - 9.5e-05 22.1 0.2 0.24 11.1 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 CEH12401.1 - 0.00013 21.4 2.5 0.52 9.7 0.6 3.3 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 CEH12401.1 - 0.00028 20.6 0.1 0.7 9.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) DUF3987 PF13148.1 CEH12401.1 - 0.00037 19.1 1.4 0.009 14.6 1.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_14 PF13173.1 CEH12401.1 - 0.00045 20.1 0.0 3.6 7.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 CEH12401.1 - 0.00052 19.8 2.4 0.63 9.9 0.2 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.15 CEH12401.1 - 0.0013 17.4 1.0 0.24 10.0 0.0 2.6 2 1 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.7 CEH12401.1 - 0.0018 17.4 0.5 0.31 10.1 0.1 2.9 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.24 CEH12401.1 - 0.0023 18.1 0.1 1.4 9.0 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CEH12401.1 - 0.0038 16.9 0.8 1.2 8.7 0.0 3.4 4 0 0 4 4 3 1 NACHT domain MMR_HSR1 PF01926.18 CEH12401.1 - 0.0077 16.1 0.0 5 7.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 CEH12401.1 - 0.0079 16.3 0.0 6.3 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 CEH12401.1 - 0.011 15.2 0.1 2.3 7.6 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 CEH12401.1 - 0.022 14.7 0.8 5.4 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 CEH12401.1 - 0.023 14.2 0.1 2.4 7.6 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.1 CEH12401.1 - 0.033 13.2 0.0 4.3 6.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 CEH12401.1 - 0.034 14.6 0.2 12 6.4 0.0 2.8 2 1 0 2 2 2 0 Miro-like protein NB-ARC PF00931.17 CEH12401.1 - 0.034 12.9 0.0 3.6 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.13 CEH12401.1 - 0.11 12.0 0.0 8.9 5.8 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family bPH_3 PF14470.1 CEH12402.1 - 0.033 14.4 0.0 0.051 13.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain WWbp PF10349.4 CEH12402.1 - 0.089 13.6 9.1 3.1 8.7 6.2 2.4 1 1 0 1 1 1 0 WW-domain ligand protein Med3 PF11593.3 CEH12402.1 - 0.66 9.1 7.7 1 8.5 5.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RAP1 PF07218.6 CEH12402.1 - 6.2 4.7 6.5 8.4 4.3 4.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_2 PF13347.1 CEH12403.1 - 1.1e-06 27.3 19.8 1.1e-06 27.3 13.7 1.7 2 0 0 2 2 2 1 MFS/sugar transport protein ADH_zinc_N_2 PF13602.1 CEH12404.1 - 1.8e-07 32.0 0.0 6.6e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CEH12404.1 - 0.00023 20.7 0.0 0.00058 19.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH12404.1 - 0.0058 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DPBB_1 PF03330.13 CEH12405.1 - 0.0029 17.5 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Mito_carr PF00153.22 CEH12406.1 - 2e-50 168.4 5.8 4.1e-17 61.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 CEH12406.1 - 0.00096 19.0 0.0 1.7 8.5 0.0 3.2 3 0 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF2620 PF10941.3 CEH12406.1 - 0.66 10.0 3.2 0.74 9.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF2620 CHRD PF07452.7 CEH12409.1 - 3e-19 69.7 0.0 2.2e-08 34.7 0.0 2.9 2 1 0 2 2 2 2 CHRD domain PTH2 PF01981.11 CEH12410.1 - 0.0024 17.5 0.2 0.0059 16.2 0.1 1.9 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Zein-binding PF04576.10 CEH12410.1 - 0.063 13.4 0.2 0.19 11.8 0.1 1.9 1 0 0 1 1 1 0 Zein-binding TCTP PF00838.12 CEH12411.1 - 5.4e-65 218.3 1.0 6e-65 218.2 0.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein GerPC PF10737.4 CEH12411.1 - 0.03 14.1 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Spore germination protein GerPC MFS_1 PF07690.11 CEH12412.1 - 8.2e-34 116.8 38.9 3.6e-32 111.4 24.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH12412.1 - 2.4e-09 36.2 27.3 2.4e-09 36.2 18.9 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter Mem_trans PF03547.13 CEH12412.1 - 4.2e-07 28.6 0.0 9e-05 20.9 0.0 2.3 2 0 0 2 2 2 2 Membrane transport protein Abhydrolase_6 PF12697.2 CEH12413.1 - 1.3e-22 80.7 0.8 1.3e-22 80.7 0.6 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH12413.1 - 2.2e-06 27.4 0.0 4.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 CEH12414.1 - 1.1e-16 60.4 19.7 3.2e-15 55.7 4.1 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH12414.1 - 1.6e-05 23.7 0.0 2.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 CEH12414.1 - 0.058 11.7 13.2 0.43 8.9 6.3 2.8 3 0 0 3 3 3 0 MFS/sugar transport protein Palm_thioest PF02089.10 CEH12415.1 - 5.3e-56 189.6 0.0 7e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 CEH12415.1 - 0.0002 21.3 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CEH12415.1 - 0.0024 16.9 0.0 0.006 15.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 CEH12415.1 - 0.0025 17.3 0.0 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold ox_reductase_C PF08635.5 CEH12416.1 - 3.5e-73 243.6 0.1 5e-73 243.1 0.1 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 CEH12416.1 - 4.8e-23 81.9 0.0 1e-22 80.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CEH12416.1 - 0.074 12.8 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Ank_2 PF12796.2 CEH12417.1 - 1.8e-24 85.8 12.2 1.4e-09 38.1 0.1 7.3 4 2 3 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEH12417.1 - 1.6e-17 63.4 2.9 0.00094 19.6 0.0 7.5 7 2 1 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 CEH12417.1 - 2.7e-15 55.3 19.0 3.2e-06 26.6 0.0 10.7 12 0 0 12 12 12 2 Ankyrin repeat Ank_3 PF13606.1 CEH12417.1 - 7e-12 44.3 0.7 0.0029 17.6 0.0 7.6 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.1 CEH12417.1 - 2.6e-11 43.3 7.1 0.44 10.8 0.0 8.2 6 1 2 8 8 8 3 Ankyrin repeats (many copies) adh_short_C2 PF13561.1 CEH12418.1 - 7e-17 61.9 3.1 6.9e-10 39.0 0.5 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEH12418.1 - 6.5e-15 55.4 7.7 4.9e-12 46.0 1.4 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CEH12418.1 - 8.9e-06 25.4 5.2 0.00015 21.4 0.6 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 CEH12418.1 - 0.029 13.7 2.6 0.33 10.3 1.8 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MDM31_MDM32 PF08118.6 CEH12419.1 - 1.6e-122 409.5 0.4 3.2e-62 210.6 0.0 3.1 3 0 0 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins LisH PF08513.6 CEH12420.1 - 1.4e-05 24.6 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 LisH ArgJ PF01960.13 CEH12421.1 - 1.9e-129 431.4 0.0 2.1e-129 431.3 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Ribosomal_S13 PF00416.17 CEH12422.1 - 2.6e-25 88.9 0.0 3.4e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CEH12422.1 - 0.0025 16.4 0.0 0.0035 15.9 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Acyltransferase PF01553.16 CEH12424.1 - 2.1e-18 66.0 0.0 2.9e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Glyco_hydro_16 PF00722.16 CEH12425.1 - 7.2e-36 123.2 1.0 1e-35 122.7 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pilin PF00114.14 CEH12425.1 - 0.07 13.8 1.9 0.1 13.2 0.3 2.0 2 1 0 2 2 2 0 Pilin (bacterial filament) Toxin_56 PF15534.1 CEH12425.1 - 0.13 12.8 0.3 0.31 11.5 0.2 1.6 1 0 0 1 1 1 0 Putative toxin 56 zf-C2H2 PF00096.21 CEH12428.1 - 8.9e-06 25.7 9.3 0.023 15.0 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEH12428.1 - 2.5e-05 24.3 7.8 0.0034 17.6 1.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEH12428.1 - 0.064 13.6 10.2 0.56 10.6 1.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger F-box-like PF12937.2 CEH12429.1 - 8.6e-10 38.1 1.1 8.6e-10 38.1 0.8 2.3 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.1 CEH12429.1 - 1.3e-06 27.8 4.4 9.6 6.6 0.0 7.9 9 0 0 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.28 CEH12429.1 - 2.6e-05 23.6 13.5 14 6.1 0.0 8.1 7 2 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.2 CEH12429.1 - 0.00037 20.0 6.3 4.9 6.8 0.0 6.1 3 2 2 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.28 CEH12429.1 - 0.001 18.6 1.1 0.42 10.3 0.1 3.6 3 0 0 3 3 3 1 F-box domain STAS_2 PF13466.1 CEH12429.1 - 0.028 14.4 2.9 2.5 8.1 0.1 3.4 1 1 1 2 2 2 0 STAS domain PP2C PF00481.16 CEH12430.1 - 3.7e-67 226.3 0.5 1.6e-51 175.1 0.3 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C STN1_2 PF09170.5 CEH12431.1 - 0.079 12.7 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 B9-C2 PF07162.6 CEH12432.1 - 0.0029 17.4 0.1 0.0036 17.0 0.1 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein GN3L_Grn1 PF08701.6 CEH12433.1 - 6.6e-24 83.6 20.3 6.6e-24 83.6 14.0 3.5 3 0 0 3 3 3 1 GNL3L/Grn1 putative GTPase SDA1 PF05285.7 CEH12433.1 - 0.0033 16.7 24.5 0.0033 16.7 17.0 3.9 3 1 1 4 4 4 1 SDA1 MMR_HSR1 PF01926.18 CEH12433.1 - 0.059 13.3 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase zf-CCHC PF00098.18 CEH12434.1 - 5.4e-29 98.7 47.1 8.9e-07 28.5 1.4 6.8 6 1 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.1 CEH12434.1 - 7.2e-08 31.9 32.5 0.023 14.3 0.4 5.8 6 0 0 6 6 6 5 Zinc knuckle eIF3g PF12353.3 CEH12434.1 - 0.12 12.2 0.0 0.12 12.2 0.0 3.9 3 1 1 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.1 CEH12434.1 - 0.13 12.0 31.2 1.6 8.4 0.2 6.0 2 2 3 5 5 5 0 Zinc knuckle zf-CCHC_2 PF13696.1 CEH12434.1 - 5.2 6.6 35.5 3.2 7.3 0.4 6.3 4 2 2 6 6 6 0 Zinc knuckle RMF PF04957.7 CEH12434.1 - 5.8 6.6 10.4 3.2 7.5 0.2 3.8 3 1 1 4 4 4 0 Ribosome modulation factor CHCH PF06747.8 CEH12435.1 - 0.0014 18.5 3.1 0.0014 18.5 2.1 2.3 2 0 0 2 2 2 1 CHCH domain Pet191_N PF10203.4 CEH12435.1 - 0.65 10.0 9.1 2.7 8.1 5.2 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.3 CEH12435.1 - 4.1 7.6 5.6 1.4 9.1 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Cmc1 PF08583.5 CEH12435.1 - 8.4 6.2 12.0 2.1 8.1 1.9 2.7 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like TGS PF02824.16 CEH12436.1 - 2.8e-20 71.8 0.0 5.7e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CEH12436.1 - 4.1e-18 65.4 0.1 1.3e-17 63.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEH12436.1 - 3e-09 36.3 0.2 1e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 CEH12436.1 - 0.0077 16.7 0.0 0.026 15.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CEH12436.1 - 0.013 15.2 0.4 0.42 10.4 0.0 2.4 1 1 1 2 2 2 0 Dynamin family ArgK PF03308.11 CEH12436.1 - 0.046 12.4 0.5 0.1 11.3 0.3 1.6 1 0 0 1 1 1 0 ArgK protein MOSP_C PF02722.10 CEH12436.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal region GTP_EFTU PF00009.22 CEH12436.1 - 0.097 12.0 0.4 7.5 5.9 0.0 2.8 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Slu7 PF11708.3 CEH12437.1 - 4.3e-71 239.4 17.0 4.3e-71 239.4 11.8 2.2 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor SR-25 PF10500.4 CEH12437.1 - 0.0059 16.1 22.4 0.0059 16.1 15.5 2.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 CEH12437.1 - 3.8 5.6 25.9 0.033 12.5 10.0 2.2 2 0 0 2 2 2 0 Transmembrane protein EF-hand_1 PF00036.27 CEH12438.1 - 4.7e-27 91.2 14.1 2.2e-07 29.6 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CEH12438.1 - 2.7e-23 81.8 3.5 7.3e-11 42.0 0.9 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEH12438.1 - 9e-20 68.7 9.3 1.7e-05 24.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CEH12438.1 - 1.2e-19 68.7 14.9 3.9e-06 25.9 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CEH12438.1 - 3.7e-13 48.8 17.1 0.0003 20.3 1.5 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CEH12438.1 - 4.9e-05 23.3 0.0 0.0076 16.2 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CEH12438.1 - 0.00011 21.9 7.4 0.025 14.3 0.4 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CEH12438.1 - 0.00055 19.7 0.1 0.84 9.5 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain VCBS PF13517.1 CEH12438.1 - 0.019 15.2 0.9 4.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella ABC_tran PF00005.22 CEH12439.1 - 2.7e-38 131.3 0.6 8e-19 68.3 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CEH12439.1 - 4.8e-13 49.7 0.1 0.0015 18.5 0.0 4.3 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 CEH12439.1 - 1.8e-07 30.6 0.1 0.11 11.7 0.0 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CEH12439.1 - 5.9e-07 28.9 0.2 0.057 12.9 0.0 3.1 2 1 1 3 3 3 2 P-loop containing region of AAA domain AAA PF00004.24 CEH12439.1 - 6e-05 23.2 0.3 0.35 11.0 0.0 3.4 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CEH12439.1 - 0.0001 21.9 1.0 0.18 11.5 0.1 4.3 4 0 0 4 4 4 1 Part of AAA domain DUF258 PF03193.11 CEH12439.1 - 0.00012 21.3 0.0 0.036 13.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 CEH12439.1 - 0.00023 21.5 3.8 0.72 10.1 0.1 3.3 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CEH12439.1 - 0.0003 20.2 3.4 0.57 9.5 0.9 3.5 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 CEH12439.1 - 0.00042 20.0 0.0 0.49 10.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 CEH12439.1 - 0.00042 20.4 0.3 0.8 9.8 0.1 3.6 2 2 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CEH12439.1 - 0.00043 20.2 0.8 1.4 8.8 0.0 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 CEH12439.1 - 0.00052 20.0 2.2 1.3 8.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CEH12439.1 - 0.00071 19.6 0.2 0.00071 19.6 0.1 3.9 3 2 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 CEH12439.1 - 0.00086 20.1 2.4 1.1 10.0 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CEH12439.1 - 0.0013 18.4 0.1 3.9 7.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 CEH12439.1 - 0.0032 17.3 0.0 0.025 14.4 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 CEH12439.1 - 0.0058 16.3 0.0 0.94 9.1 0.0 3.1 4 0 0 4 4 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 CEH12439.1 - 0.0067 16.1 0.0 0.41 10.3 0.0 3.0 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.17 CEH12439.1 - 0.0079 16.3 0.0 4.5 7.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 CEH12439.1 - 0.031 14.1 11.1 0.19 11.6 0.1 4.1 4 2 0 4 4 4 0 AAA domain SRP54 PF00448.17 CEH12439.1 - 0.053 12.9 0.2 5.3 6.4 0.1 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 CEH12439.1 - 0.068 13.0 0.0 27 4.6 0.0 3.3 4 0 0 4 4 3 0 AAA domain Miro PF08477.8 CEH12439.1 - 0.073 13.5 0.0 3.9 8.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 CEH12439.1 - 0.16 11.6 2.2 8.4 6.0 0.0 3.2 4 0 0 4 4 4 0 Archaeal ATPase ABC_tran_2 PF12848.2 CEH12439.1 - 2.6 7.9 11.2 0.094 12.5 3.0 2.2 2 0 0 2 2 1 0 ABC transporter PSD5 PF07637.6 CEH12440.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) DNA_binding_1 PF01035.15 CEH12440.1 - 0.38 10.5 1.4 13 5.6 0.1 2.1 1 1 1 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain PhzC-PhzF PF02567.11 CEH12441.1 - 4.3e-40 137.7 0.0 1.6e-39 135.8 0.0 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 CEH12441.1 - 0.0026 16.6 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Proline racemase UDPGP PF01704.13 CEH12442.1 - 3.4e-180 599.0 0.3 4e-180 598.8 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Aldedh PF00171.17 CEH12443.1 - 1.4e-105 353.3 0.1 1.6e-105 353.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA PF00004.24 CEH12444.1 - 5.7e-53 178.6 0.0 1.9e-39 134.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEH12444.1 - 3.5e-09 36.8 0.1 0.00067 19.8 0.1 3.3 2 1 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 CEH12444.1 - 1.2e-08 34.4 0.1 7.5e-07 28.7 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.9 CEH12444.1 - 1.5e-08 34.7 0.0 9.2e-06 25.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CEH12444.1 - 1e-07 31.7 0.1 0.0015 18.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CEH12444.1 - 3.3e-07 29.5 0.3 0.0089 15.1 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CEH12444.1 - 4.2e-07 30.1 0.1 0.021 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 CEH12444.1 - 7.1e-07 29.1 0.0 0.047 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CEH12444.1 - 1.1e-06 28.5 0.0 0.054 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CEH12444.1 - 1.3e-06 29.2 0.1 0.0078 17.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 CEH12444.1 - 1.5e-06 27.5 0.4 0.0052 15.9 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CEH12444.1 - 1.5e-06 27.8 0.5 0.076 12.7 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain TIP49 PF06068.8 CEH12444.1 - 1.7e-06 27.0 0.1 0.039 12.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 CEH12444.1 - 4.5e-06 27.0 0.3 0.013 15.7 0.0 3.6 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 CEH12444.1 - 1e-05 25.6 0.0 0.048 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 CEH12444.1 - 1.2e-05 24.8 2.8 0.12 11.7 0.2 3.6 2 2 1 3 3 3 2 AAA domain AAA_24 PF13479.1 CEH12444.1 - 1.5e-05 24.6 1.6 0.051 13.1 0.1 2.7 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CEH12444.1 - 3.3e-05 23.3 2.5 0.048 13.0 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 CEH12444.1 - 5.7e-05 22.6 0.0 0.77 9.2 0.0 3.2 3 0 0 3 3 3 2 Sigma-54 interaction domain NACHT PF05729.7 CEH12444.1 - 6.1e-05 22.7 1.3 0.096 12.3 0.0 3.4 4 0 0 4 4 3 1 NACHT domain KaiC PF06745.8 CEH12444.1 - 9.2e-05 21.6 0.1 0.007 15.5 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_30 PF13604.1 CEH12444.1 - 0.00019 21.0 0.0 0.49 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 CEH12444.1 - 0.0002 20.6 0.0 0.29 10.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Zeta_toxin PF06414.7 CEH12444.1 - 0.00029 19.9 0.2 0.71 8.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 CEH12444.1 - 0.00032 21.0 0.4 0.09 13.0 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_3 PF07726.6 CEH12444.1 - 0.00059 19.4 0.0 0.095 12.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 CEH12444.1 - 0.00059 19.4 0.0 0.69 9.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 CEH12444.1 - 0.0013 18.7 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 CEH12444.1 - 0.0016 17.3 0.0 0.75 8.6 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 CEH12444.1 - 0.003 17.1 0.1 0.55 9.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 CEH12444.1 - 0.0053 15.7 0.0 0.69 8.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 CEH12444.1 - 0.0066 16.1 0.3 12 5.4 0.0 3.4 2 2 1 3 3 3 0 Archaeal ATPase KTI12 PF08433.5 CEH12444.1 - 0.011 15.0 0.0 0.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NB-ARC PF00931.17 CEH12444.1 - 0.022 13.6 0.3 2.8 6.7 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain DAP3 PF10236.4 CEH12444.1 - 0.026 13.4 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.10 CEH12444.1 - 0.028 14.2 0.0 7.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 CEH12444.1 - 0.037 14.0 0.0 13 5.8 0.0 3.3 3 1 0 3 3 2 0 Sigma-54 interaction domain CDC48_N PF02359.13 CEH12444.1 - 0.041 13.8 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Zot PF05707.7 CEH12444.1 - 0.14 11.6 0.0 6.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) cobW PF02492.14 CEH12444.1 - 0.16 11.3 0.5 6.4 6.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Proteasome PF00227.21 CEH12445.1 - 4.2e-43 146.8 0.1 4.8e-43 146.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Myb_DNA-binding PF00249.26 CEH12446.1 - 1.9e-10 40.6 0.4 4e-10 39.5 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH12446.1 - 7.2e-07 29.2 1.2 1.8e-06 27.9 0.9 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain COX14 PF14880.1 CEH12448.1 - 0.0017 17.8 0.9 0.0017 17.8 0.6 1.6 2 0 0 2 2 2 1 Cytochrome oxidase c assembly GDPD PF03009.12 CEH12449.1 - 1.9e-32 112.8 0.0 2.9e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 CEH12449.1 - 0.054 13.7 1.3 0.054 13.7 0.9 2.6 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family PPI_Ypi1 PF07491.6 CEH12450.1 - 6.6e-24 83.2 3.1 6.6e-24 83.2 2.2 3.0 3 1 0 3 3 3 1 Protein phosphatase inhibitor YtpI PF14007.1 CEH12452.1 - 0.16 11.8 0.6 0.24 11.3 0.4 1.3 1 0 0 1 1 1 0 YtpI-like protein RNase_H PF00075.19 CEH12454.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 RNase H Med18 PF09637.5 CEH12454.1 - 0.087 12.3 0.2 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Med18 protein Complex1_LYR_1 PF13232.1 CEH12456.1 - 5.7e-09 36.0 0.3 1.7e-08 34.5 0.2 1.9 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CEH12456.1 - 5.4e-08 32.5 0.1 1.3e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ribosomal_L31 PF01197.13 CEH12456.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L31 FAD_binding_2 PF00890.19 CEH12456.1 - 0.27 10.0 4.6 0.049 12.4 0.3 1.7 2 0 0 2 2 2 0 FAD binding domain 3-HAO PF06052.7 CEH12457.1 - 4.2e-57 191.8 0.0 4.8e-57 191.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 CEH12457.1 - 2.1e-06 27.1 0.0 3.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 CEH12457.1 - 0.0015 17.9 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 CEH12457.1 - 0.04 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain zf-piccolo PF05715.8 CEH12457.1 - 0.085 12.8 0.3 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger zf-ribbon_3 PF13248.1 CEH12457.1 - 0.31 10.2 1.4 1.1 8.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CEH12457.1 - 1.7 8.2 5.1 2 8.0 0.0 3.2 4 0 0 4 4 4 0 zinc-ribbon domain Adaptin_N PF01602.15 CEH12458.1 - 3.3e-121 405.2 10.5 4.2e-121 404.8 7.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 CEH12458.1 - 2.7e-41 140.0 0.1 8e-41 138.5 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 CEH12458.1 - 2.3e-13 50.4 0.0 7e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain Leo1 PF04004.8 CEH12459.1 - 3.4e-41 140.7 0.3 3.4e-41 140.7 0.2 2.3 3 0 0 3 3 3 1 Leo1-like protein Glyco_hydro_cc PF11790.3 CEH12460.1 - 1.1e-50 172.2 1.5 1.3e-50 172.1 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 CEH12460.1 - 0.00045 19.1 0.0 0.00056 18.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.13 CEH12460.1 - 0.021 14.0 0.3 0.03 13.5 0.2 1.4 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Pmp3 PF01679.12 CEH12461.1 - 5.5e-18 64.4 7.9 6.2e-18 64.2 5.4 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pmp3 PF01679.12 CEH12462.1 - 7.2e-22 76.8 6.4 8.4e-22 76.6 4.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Fungal_trans PF04082.13 CEH12466.1 - 5.1e-13 48.4 0.1 7.3e-13 47.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH12466.1 - 1.1e-07 31.6 6.6 3.1e-07 30.1 4.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 CEH12467.1 - 4.5e-43 147.2 35.4 5e-42 143.8 24.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CEH12467.1 - 1.9e-14 52.7 17.0 3e-14 52.1 11.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) VHS PF00790.14 CEH12469.1 - 1.1e-37 128.7 0.2 3e-37 127.3 0.0 1.8 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 CEH12469.1 - 1.4e-15 56.9 5.5 2.5e-15 56.1 3.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 CEH12469.1 - 7e-06 25.1 7.1 0.0061 16.0 1.5 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif Hist_deacetyl PF00850.14 CEH12470.1 - 2.5e-77 260.2 0.0 3.4e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain WD40 PF00400.27 CEH12471.1 - 1.3e-55 183.3 15.5 7.8e-13 47.7 0.4 7.2 6 1 1 7 7 7 7 WD domain, G-beta repeat Nbas_N PF15492.1 CEH12471.1 - 0.00022 20.4 0.0 0.022 13.8 0.0 2.4 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 CEH12471.1 - 0.0012 17.2 0.0 0.0081 14.4 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.6 CEH12471.1 - 0.008 15.9 0.0 1 9.0 0.0 3.0 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CEH12471.1 - 0.045 12.4 0.1 0.72 8.5 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 CEH12471.1 - 0.064 11.3 0.4 1.4 6.9 0.0 2.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Acyl-CoA_dh_N PF02771.11 CEH12474.1 - 8e-25 87.6 0.0 1.4e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 CEH12474.1 - 1.6e-24 86.6 0.0 2.6e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEH12474.1 - 1.2e-17 63.0 0.0 2.4e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CEH12474.1 - 6.7e-10 39.3 0.1 1.5e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Init_tRNA_PT PF04179.7 CEH12475.1 - 1.8e-39 135.8 0.0 3.9e-29 101.8 0.0 2.1 1 1 1 2 2 2 2 Initiator tRNA phosphoribosyl transferase zf-U1 PF06220.7 CEH12476.1 - 6.9e-19 67.1 6.9 9.3e-19 66.7 4.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 CEH12476.1 - 0.0045 17.1 3.7 0.0078 16.3 2.6 1.4 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Flavokinase PF01687.12 CEH12477.1 - 1.7e-24 86.0 0.2 5e-23 81.3 0.1 2.0 1 1 0 1 1 1 1 Riboflavin kinase Cullin_binding PF03556.10 CEH12478.1 - 4e-32 110.7 0.1 5.7e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 CEH12478.1 - 2.2e-08 33.5 0.2 3.8e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain Cu-oxidase_3 PF07732.10 CEH12479.1 - 3.7e-32 110.5 0.8 9.7e-32 109.1 0.5 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 CEH12479.1 - 6e-19 68.4 0.0 1.5e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CEH12479.1 - 7.8e-19 67.5 12.8 4.5e-14 52.1 3.8 3.9 2 2 0 2 2 2 2 Multicopper oxidase HMG_box_2 PF09011.5 CEH12480.1 - 1.1e-19 70.6 8.7 2.5e-09 37.3 0.4 2.8 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 CEH12480.1 - 2.9e-19 69.0 13.2 3.7e-11 43.1 1.6 3.2 3 1 0 3 3 3 2 HMG (high mobility group) box DUF1561 PF07598.6 CEH12480.1 - 0.019 12.9 0.0 0.027 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) YABBY PF04690.8 CEH12480.1 - 0.58 10.3 10.9 0.037 14.2 3.5 2.0 2 1 1 3 3 3 0 YABBY protein Zn_clus PF00172.13 CEH12481.1 - 0.0022 17.8 14.6 0.0026 17.6 7.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 CEH12482.1 - 9.9e-38 129.7 0.0 1.4e-21 76.8 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain SWIB PF02201.13 CEH12482.1 - 4.9e-24 83.8 0.0 1.8e-23 82.0 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain Pkinase_Tyr PF07714.12 CEH12482.1 - 3.7e-14 52.4 0.0 2.8e-11 42.9 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase DEK_C PF08766.6 CEH12482.1 - 0.00061 19.5 0.1 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 DEK C terminal domain Kinase-like PF14531.1 CEH12482.1 - 0.076 11.9 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Kinase-like DUF722 PF05263.6 CEH12482.1 - 0.11 12.6 0.1 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF722) CRAL_TRIO PF00650.15 CEH12483.1 - 4.3e-35 120.5 0.0 7.7e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEH12483.1 - 3.1e-12 46.4 0.9 3.1e-12 46.4 0.6 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CEH12483.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF2247 PF10004.4 CEH12483.1 - 0.53 9.9 3.6 0.24 11.0 0.4 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) Isochorismatase PF00857.15 CEH12484.1 - 1.6e-28 99.8 0.1 2.9e-28 98.9 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family DUF1009 PF06230.6 CEH12484.1 - 0.074 12.3 0.1 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1009) Iso_dh PF00180.15 CEH12485.1 - 1.3e-99 333.4 0.0 1.7e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BRCT PF00533.21 CEH12486.1 - 1.5e-07 31.4 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CEH12486.1 - 8.4e-07 28.7 0.0 5.5e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 CEH12486.1 - 0.0013 18.8 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 CEH12486.1 - 0.0074 16.0 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) NmrA PF05368.8 CEH12487.1 - 3.2e-07 29.8 0.0 1.4e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family DUF2051 PF09738.4 CEH12487.1 - 0.1 11.8 0.3 0.18 11.0 0.2 1.3 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) DUF500 PF04366.7 CEH12489.1 - 5.2e-33 113.1 0.0 1.1e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) Mob1_phocein PF03637.12 CEH12490.1 - 4.7e-58 195.7 0.5 6e-58 195.3 0.3 1.1 1 0 0 1 1 1 1 Mob1/phocein family Rhodanese PF00581.15 CEH12491.1 - 1e-05 25.8 0.0 0.0003 21.1 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain zf-CCHC PF00098.18 CEH12493.1 - 1.2e-07 31.3 0.8 2e-07 30.6 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CEH12493.1 - 0.042 13.5 0.2 0.079 12.6 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle MerR-DNA-bind PF09278.6 CEH12493.1 - 0.52 10.7 5.2 0.53 10.7 0.0 2.6 2 0 0 2 2 2 0 MerR, DNA binding Myb_DNA-binding PF00249.26 CEH12495.1 - 0.017 15.1 0.1 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain GATase PF00117.23 CEH12496.1 - 1.2e-05 24.8 0.2 4.7e-05 22.9 0.1 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I YEATS PF03366.11 CEH12497.1 - 5.2e-31 106.2 0.6 4.2e-30 103.3 0.4 2.1 1 1 0 1 1 1 1 YEATS family Pox_A_type_inc PF04508.7 CEH12497.1 - 4.7 7.2 6.9 7.9 6.5 4.8 1.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat NAD_binding_8 PF13450.1 CEH12499.1 - 2.7e-13 49.7 0.6 6.1e-13 48.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CEH12499.1 - 5.3e-10 38.9 0.3 2e-05 23.8 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 CEH12499.1 - 1.6e-06 28.3 0.1 0.00082 19.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEH12499.1 - 7.9e-06 25.7 0.1 0.016 14.9 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 CEH12499.1 - 8.5e-06 24.8 1.2 1.5e-05 24.1 0.1 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEH12499.1 - 6.5e-05 21.9 0.3 0.00014 20.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CEH12499.1 - 0.0013 19.0 0.2 0.0039 17.5 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEH12499.1 - 0.018 13.5 0.1 0.084 11.3 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 CEH12499.1 - 0.024 13.5 0.1 0.04 12.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CEH12499.1 - 0.026 14.4 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CEH12499.1 - 0.033 13.2 0.1 0.053 12.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AAA_5 PF07728.9 CEH12502.1 - 1.2e-115 381.4 0.0 1.2e-20 73.7 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 CEH12502.1 - 1.2e-27 96.7 0.0 0.0067 16.6 0.0 7.6 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 CEH12502.1 - 9.5e-26 89.9 0.0 3.5e-07 29.9 0.0 7.7 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEH12502.1 - 9.2e-23 80.8 5.8 0.00029 20.9 0.1 8.5 8 1 0 8 8 6 5 AAA domain AAA_17 PF13207.1 CEH12502.1 - 5.3e-20 72.4 0.0 0.31 11.8 0.0 7.5 6 0 0 6 6 6 5 AAA domain AAA_33 PF13671.1 CEH12502.1 - 1.9e-19 69.9 4.7 0.0031 17.4 0.0 8.5 7 0 0 7 7 7 3 AAA domain AAA_18 PF13238.1 CEH12502.1 - 8.4e-17 61.6 1.0 0.82 9.9 0.0 7.3 7 0 0 7 7 6 4 AAA domain Zeta_toxin PF06414.7 CEH12502.1 - 8.5e-17 60.9 0.4 0.0083 15.2 0.0 6.8 6 0 0 6 6 6 4 Zeta toxin AAA_19 PF13245.1 CEH12502.1 - 1.5e-15 56.7 14.2 0.034 13.8 0.2 7.8 7 0 0 7 7 6 5 Part of AAA domain Sigma54_activat PF00158.21 CEH12502.1 - 4.2e-14 52.3 0.1 0.003 17.0 0.0 6.3 7 0 0 7 7 7 3 Sigma-54 interaction domain ABC_tran PF00005.22 CEH12502.1 - 5.7e-14 52.5 0.0 0.12 12.6 0.0 6.7 6 0 0 6 6 6 3 ABC transporter AAA_14 PF13173.1 CEH12502.1 - 1.8e-13 50.4 0.0 0.00054 19.8 0.0 6.3 7 0 0 7 7 5 2 AAA domain AAA_28 PF13521.1 CEH12502.1 - 2.4e-13 50.3 3.0 0.57 10.1 0.0 8.3 7 0 0 7 7 7 2 AAA domain T2SE PF00437.15 CEH12502.1 - 2.7e-13 49.4 0.0 0.02 13.8 0.0 6.7 6 0 0 6 6 6 2 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 CEH12502.1 - 5.5e-13 49.1 2.4 0.00082 19.4 0.1 6.8 6 0 0 6 6 6 2 Sigma-54 interaction domain UPF0079 PF02367.12 CEH12502.1 - 7.4e-13 48.2 1.6 0.17 11.5 0.0 6.5 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 CEH12502.1 - 2.1e-10 40.8 68.8 0.0016 18.4 2.3 12.4 11 2 1 12 12 9 6 AAA ATPase domain RNA_helicase PF00910.17 CEH12502.1 - 5.9e-10 39.2 0.1 5 7.3 0.0 6.5 6 0 0 6 6 6 0 RNA helicase AAA_29 PF13555.1 CEH12502.1 - 2e-09 36.8 0.0 1.6 8.2 0.0 6.6 6 0 0 6 6 6 2 P-loop containing region of AAA domain Miro PF08477.8 CEH12502.1 - 7.7e-09 36.0 0.0 3.9 7.9 0.0 5.7 5 0 0 5 5 5 0 Miro-like protein DUF258 PF03193.11 CEH12502.1 - 1.8e-07 30.4 0.0 3.7 6.7 0.0 5.3 6 0 0 6 6 6 0 Protein of unknown function, DUF258 NACHT PF05729.7 CEH12502.1 - 4.4e-07 29.7 8.7 0.75 9.4 0.0 7.1 8 0 0 8 8 6 1 NACHT domain AAA_23 PF13476.1 CEH12502.1 - 4.4e-07 30.4 10.7 0.76 10.0 0.0 7.1 8 0 0 8 8 6 2 AAA domain RuvB_N PF05496.7 CEH12502.1 - 2.5e-06 26.7 3.6 0.25 10.3 0.0 6.0 6 0 0 6 6 6 1 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 CEH12502.1 - 2.7e-06 27.1 0.1 3.1 7.5 0.0 5.5 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 CEH12502.1 - 1.5e-05 24.5 3.9 0.99 8.8 0.1 4.7 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain DUF815 PF05673.8 CEH12502.1 - 1.6e-05 23.9 0.5 2.3 7.0 0.0 4.9 5 0 0 5 5 5 1 Protein of unknown function (DUF815) cobW PF02492.14 CEH12502.1 - 1.6e-05 24.3 2.1 1.4 8.3 0.0 5.8 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CEH12502.1 - 1.7e-05 24.3 1.1 2.6 7.5 0.0 5.0 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 CEH12502.1 - 0.0003 20.5 1.8 14 5.3 0.0 5.5 6 0 0 6 6 6 0 NTPase TIP49 PF06068.8 CEH12502.1 - 0.00073 18.3 1.3 0.2 10.3 0.0 4.0 4 0 0 4 4 4 1 TIP49 C-terminus Rad17 PF03215.10 CEH12502.1 - 0.0011 17.8 2.0 0.7 8.5 0.0 4.8 6 0 0 6 6 6 1 Rad17 cell cycle checkpoint protein SRPRB PF09439.5 CEH12502.1 - 0.004 16.3 0.1 26 3.9 0.0 5.2 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 CEH12502.1 - 0.0054 16.4 0.0 0.8 9.3 0.0 3.9 5 0 0 5 5 3 1 Archaeal ATPase MMR_HSR1 PF01926.18 CEH12502.1 - 0.0075 16.2 0.0 17 5.3 0.0 4.8 5 0 0 5 5 5 0 50S ribosome-binding GTPase DEAD PF00270.24 CEH12502.1 - 0.0077 15.7 4.9 6.1 6.3 0.0 4.5 5 0 0 5 5 3 0 DEAD/DEAH box helicase vWA-TerF-like PF10138.4 CEH12502.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus ResIII PF04851.10 CEH12502.1 - 0.02 14.7 0.0 15 5.3 0.0 3.8 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 CEH12502.1 - 0.079 12.4 0.0 4.6 6.6 0.0 3.1 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_6 PF12774.2 CEH12502.1 - 0.15 11.5 0.0 91 2.4 0.0 4.9 6 0 0 6 6 5 0 Hydrolytic ATP binding site of dynein motor region D1 Gtr1_RagA PF04670.7 CEH12502.1 - 0.16 11.0 0.7 6.7 5.7 0.0 3.9 5 0 0 5 5 5 0 Gtr1/RagA G protein conserved region KaiC PF06745.8 CEH12502.1 - 0.17 10.9 0.0 15 4.6 0.0 3.8 4 0 0 4 4 4 0 KaiC Parvo_NS1 PF01057.12 CEH12502.1 - 0.34 9.7 0.0 4 6.2 0.0 2.6 4 0 0 4 4 3 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 CEH12502.1 - 0.37 9.9 3.2 15 4.7 0.0 3.7 4 0 0 4 4 4 0 PhoH-like protein AAA_7 PF12775.2 CEH12502.1 - 0.4 9.7 0.0 18 4.2 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region D3 AAA_21 PF13304.1 CEH12502.1 - 0.42 10.5 0.0 67 3.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain CbiA PF01656.18 CEH12502.1 - 0.45 9.8 2.8 4.9 6.5 0.0 3.6 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 CEH12502.1 - 1.6 8.2 5.8 72 2.8 0.0 4.5 6 0 0 6 6 4 0 AAA domain FeoB_N PF02421.13 CEH12502.1 - 1.6 7.9 0.3 95 2.2 0.0 3.2 4 0 0 4 4 3 0 Ferrous iron transport protein B ATP_bind_1 PF03029.12 CEH12502.1 - 6.9 6.1 5.3 70 2.8 0.0 4.1 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein TPR_11 PF13414.1 CEH12503.1 - 1.6e-13 50.0 1.8 7.8e-09 35.0 0.0 2.9 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CEH12503.1 - 5e-07 29.0 2.8 0.0015 18.0 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.26 CEH12503.1 - 3e-06 26.8 0.0 7.7e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain UBA PF00627.26 CEH12503.1 - 1.3e-05 24.8 0.0 9e-05 22.1 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain TPR_2 PF07719.12 CEH12503.1 - 0.00017 21.2 12.5 0.0011 18.6 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apo-CII PF05355.6 CEH12503.1 - 0.47 10.3 4.5 0.19 11.6 0.4 2.4 2 0 0 2 2 2 0 Apolipoprotein C-II CPSF_A PF03178.10 CEH12504.1 - 1.9e-68 230.9 0.0 4.8e-68 229.5 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region NifW PF03206.9 CEH12504.1 - 0.17 12.0 0.3 0.64 10.1 0.0 2.1 3 0 0 3 3 3 0 Nitrogen fixation protein NifW Serglycin PF04360.7 CEH12505.1 - 0.019 14.7 7.5 0.19 11.4 0.1 3.0 2 0 0 2 2 2 0 Serglycin Abhydrolase_6 PF12697.2 CEH12506.1 - 1.2e-24 87.5 0.4 1.4e-24 87.2 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH12506.1 - 3.9e-12 46.1 0.3 2e-11 43.8 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH12506.1 - 7.3e-10 38.7 0.1 1.1e-08 34.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.13 CEH12507.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 CEH12508.1 - 1.8e-26 93.0 2.0 3.8e-26 92.0 1.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH12508.1 - 2.1e-13 50.3 1.8 5.2e-13 49.0 1.2 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CEH12508.1 - 8.6e-06 25.6 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CEH12508.1 - 0.0088 16.0 0.9 0.021 14.8 0.4 1.7 1 1 1 2 2 2 1 NADH(P)-binding DUF2306 PF10067.4 CEH12508.1 - 0.036 14.1 5.8 0.66 10.1 0.1 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2306) Epimerase PF01370.16 CEH12508.1 - 0.052 12.9 0.6 0.42 10.0 0.4 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CEH12508.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TauD PF02668.11 CEH12509.1 - 0.017 14.7 0.1 0.031 13.9 0.0 1.2 1 1 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 CEH12509.1 - 0.036 14.5 2.3 0.11 12.9 0.6 2.4 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Tet_JBP PF12851.2 CEH12509.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily MFS_1 PF07690.11 CEH12510.1 - 9.5e-25 87.0 47.7 9.5e-25 87.0 33.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CEH12510.1 - 0.33 10.7 7.6 0.78 9.5 3.5 3.0 2 1 1 3 3 3 0 MFS_1 like family Trp_DMAT PF11991.3 CEH12511.1 - 2.7e-53 181.4 0.0 1.7e-52 178.8 0.0 1.8 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 CEH12512.1 - 1.6e-58 198.3 0.0 6.3e-58 196.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF485 PF04341.7 CEH12512.1 - 0.053 13.2 0.1 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF485 TM140 PF14985.1 CEH12512.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 TM140 protein family Zn_clus PF00172.13 CEH12513.1 - 1.6 8.7 11.6 1.4 8.8 2.5 1.9 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.13 CEH12514.1 - 1.1e-07 31.3 0.1 1.5e-06 27.6 0.0 2.3 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF2183 PF09949.4 CEH12517.1 - 1.8e-24 85.5 0.0 4.1e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 CEH12517.1 - 0.00044 19.8 0.0 0.00081 18.9 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DSHCT PF08148.7 CEH12518.1 - 7e-61 204.6 0.4 2.1e-60 203.0 0.3 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CEH12518.1 - 8.9e-23 80.6 0.0 2.1e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 CEH12518.1 - 3.7e-12 45.9 0.1 4.2e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 rRNA-processing arch domain Helicase_C PF00271.26 CEH12518.1 - 7.9e-06 25.6 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH12518.1 - 0.0026 17.6 0.0 0.023 14.5 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit MFS_1 PF07690.11 CEH12521.1 - 5.9e-26 91.0 55.1 9.7e-23 80.4 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1634 PF07843.6 CEH12521.1 - 0.0031 17.1 2.7 0.0031 17.1 1.9 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1634) RPAP1_C PF08620.5 CEH12523.1 - 0.037 13.8 0.9 0.069 13.0 0.1 1.8 1 1 1 2 2 2 0 RPAP1-like, C-terminal DUF2173 PF09941.4 CEH12523.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) DNA_pol_E_B PF04042.11 CEH12524.1 - 2.7e-37 128.0 0.0 4.1e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B RhoGEF PF00621.15 CEH12525.1 - 1.1e-15 58.0 0.0 1.4e-11 44.6 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain Bromodomain PF00439.20 CEH12526.1 - 5e-53 176.9 0.0 1.9e-17 62.9 0.0 3.7 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 CEH12526.1 - 2.6e-05 23.5 0.0 0.014 14.5 0.0 2.7 3 0 0 3 3 3 2 Peptidase family M1 DUF3881 PF12997.2 CEH12526.1 - 0.049 12.6 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) HEAT_2 PF13646.1 CEH12526.1 - 0.091 13.0 0.0 0.091 13.0 0.0 3.8 4 1 0 4 4 4 0 HEAT repeats CENP-H PF05837.7 CEH12527.1 - 4.4e-08 33.2 0.6 1.2e-07 31.7 0.3 1.9 1 1 1 2 2 2 1 Centromere protein H (CENP-H) HTH_1 PF00126.22 CEH12527.1 - 0.063 13.0 2.1 0.93 9.2 0.1 2.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Nbl1_Borealin_N PF10444.4 CEH12528.1 - 1.9e-07 30.3 0.0 3.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal SLY PF12485.3 CEH12528.1 - 0.0042 17.3 2.1 0.0053 17.0 1.5 1.1 1 0 0 1 1 1 1 Lymphocyte signaling adaptor protein BLVR PF06375.6 CEH12528.1 - 0.042 13.6 0.7 0.052 13.3 0.5 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Med21 PF11221.3 CEH12528.1 - 0.11 12.4 0.2 0.14 12.1 0.1 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Borealin PF10512.4 CEH12529.1 - 0.00066 19.5 1.8 0.02 14.7 0.1 2.7 2 0 0 2 2 2 2 Cell division cycle-associated protein 8 Beach PF02138.13 CEH12533.1 - 2.4e-99 332.1 0.0 3.5e-99 331.6 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CEH12533.1 - 2.2e-09 37.0 0.0 4.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH FYVE PF01363.16 CEH12533.1 - 6.3e-06 25.9 4.2 1.4e-05 24.8 2.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger Laminin_G_3 PF13385.1 CEH12533.1 - 2e-05 24.8 0.0 5.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 CEH12533.1 - 8.4e-05 22.3 0.4 0.13 12.1 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3689 PF12463.3 CEH12533.1 - 0.015 14.0 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) FYVE_2 PF02318.11 CEH12533.1 - 2.2 8.1 5.9 5.8 6.8 4.1 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger CMAS PF02353.15 CEH12534.1 - 4.1e-30 104.7 0.0 1e-18 67.4 0.0 2.9 2 1 1 3 3 3 2 Mycolic acid cyclopropane synthetase ADH_N PF08240.7 CEH12535.1 - 1.3e-12 47.4 0.0 1.6e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEH12536.1 - 2.7e-13 49.5 1.2 2e-12 46.7 0.9 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TraF_2 PF13729.1 CEH12536.1 - 0.037 12.8 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Methyltransf_18 PF12847.2 CEH12536.1 - 0.074 13.6 0.9 0.14 12.7 0.5 1.4 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 CEH12537.1 - 2.7e-68 229.9 0.0 3.5e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH12537.1 - 2.8e-28 98.6 0.0 4e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH12537.1 - 0.01 15.6 0.1 0.023 14.4 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.16 CEH12538.1 - 1.3e-28 99.6 0.0 3.7e-27 94.8 0.0 2.3 2 0 0 2 2 2 2 Aldo/keto reductase family Yae1_N PF09811.4 CEH12538.1 - 2.3e-11 43.0 0.7 4.7e-11 42.0 0.5 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal zf-CCCH PF00642.19 CEH12541.1 - 1.5e-12 46.8 30.4 8.2e-05 22.1 0.8 5.4 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 CEH12541.1 - 1e-05 25.1 1.2 1e-05 25.1 0.8 2.7 3 0 0 3 3 3 1 Zinc knuckle NIF PF03031.13 CEH12542.1 - 1.5e-22 80.0 0.0 5.9e-20 71.5 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 CEH12542.1 - 3.1e-12 46.1 0.7 6.7e-12 45.0 0.1 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 CEH12542.1 - 0.00012 22.1 0.1 0.00034 20.6 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain MFS_1 PF07690.11 CEH12543.1 - 1.9e-36 125.5 21.9 1.9e-36 125.5 15.2 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily F-actin_cap_A PF01267.12 CEH12544.1 - 4.4e-62 209.6 0.0 5.5e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF2135 PF09906.4 CEH12544.1 - 0.046 13.6 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) AAA PF00004.24 CEH12546.1 - 2.3e-22 79.5 0.1 6.1e-11 42.6 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEH12546.1 - 3.9e-12 46.5 6.2 1.6e-06 28.2 0.1 3.7 3 1 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 CEH12546.1 - 2.9e-10 41.0 0.2 0.00015 22.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CEH12546.1 - 1e-07 32.1 0.4 0.0022 18.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CEH12546.1 - 1.6e-06 28.2 0.0 0.0096 16.0 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 CEH12546.1 - 2.1e-06 27.6 2.0 0.029 14.2 0.2 3.2 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 CEH12546.1 - 2.9e-06 27.6 0.0 0.041 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CEH12546.1 - 1.5e-05 24.9 0.0 0.0055 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CEH12546.1 - 2.1e-05 24.0 1.3 0.62 9.4 0.1 3.3 2 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CEH12546.1 - 3.1e-05 23.5 0.1 0.022 14.2 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CEH12546.1 - 3.5e-05 23.4 0.1 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 CEH12546.1 - 7.6e-05 23.0 0.2 0.024 14.9 0.0 3.0 2 1 0 2 2 2 1 ABC transporter DUF815 PF05673.8 CEH12546.1 - 9.5e-05 21.4 0.0 0.0051 15.7 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF815) MobB PF03205.9 CEH12546.1 - 0.00022 20.9 0.0 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CEH12546.1 - 0.00026 20.7 0.3 0.29 10.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 CEH12546.1 - 0.0003 20.8 0.1 0.088 12.8 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 CEH12546.1 - 0.0003 20.4 0.5 0.7 9.5 0.0 2.9 2 1 1 3 3 3 2 NACHT domain NTPase_1 PF03266.10 CEH12546.1 - 0.00041 20.1 0.0 0.073 12.7 0.0 2.5 2 0 0 2 2 2 1 NTPase IstB_IS21 PF01695.12 CEH12546.1 - 0.00046 19.6 0.1 0.21 10.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein APS_kinase PF01583.15 CEH12546.1 - 0.00086 19.0 0.0 0.23 11.1 0.0 3.3 2 1 1 3 3 3 1 Adenylylsulphate kinase AAA_19 PF13245.1 CEH12546.1 - 0.0015 18.2 3.2 0.76 9.5 0.0 3.5 3 1 1 4 4 3 1 Part of AAA domain KaiC PF06745.8 CEH12546.1 - 0.0018 17.4 0.0 1.4 7.9 0.0 2.4 2 0 0 2 2 2 2 KaiC RuvB_N PF05496.7 CEH12546.1 - 0.0025 16.8 0.1 0.022 13.7 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 CEH12546.1 - 0.0026 17.2 0.1 0.064 12.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CEH12546.1 - 0.0027 16.8 0.0 0.76 8.8 0.0 2.6 2 1 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 CEH12546.1 - 0.0035 17.3 3.7 0.67 9.8 0.5 3.1 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.1 CEH12546.1 - 0.0067 16.0 0.6 1.3 8.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CEH12546.1 - 0.0077 15.8 0.7 0.2 11.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 CEH12546.1 - 0.0083 15.0 0.1 0.47 9.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Mg_chelatase PF01078.16 CEH12546.1 - 0.013 14.6 0.5 0.22 10.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CbiA PF01656.18 CEH12546.1 - 0.016 14.6 0.1 0.046 13.1 0.0 1.9 3 0 0 3 3 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.12 CEH12546.1 - 0.021 14.3 0.0 0.089 12.3 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 CEH12546.1 - 0.022 14.4 0.1 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 CEH12546.1 - 0.034 13.6 0.1 0.11 11.9 0.0 1.8 2 0 0 2 2 1 0 FtsK/SpoIIIE family T2SE PF00437.15 CEH12546.1 - 0.038 12.8 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.11 CEH12546.1 - 0.04 13.0 0.1 7.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase DUF2075 PF09848.4 CEH12546.1 - 0.042 12.8 0.1 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 CEH12546.1 - 0.047 13.1 0.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain PPV_E1_C PF00519.12 CEH12546.1 - 0.066 11.8 0.0 0.51 8.8 0.0 1.9 2 0 0 2 2 2 0 Papillomavirus helicase AAA_3 PF07726.6 CEH12546.1 - 0.068 12.7 0.0 0.64 9.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 CEH12546.1 - 0.076 11.7 0.1 0.47 9.1 0.0 2.2 3 0 0 3 3 2 0 TIP49 C-terminus cobW PF02492.14 CEH12546.1 - 0.079 12.3 0.0 9.1 5.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.17 CEH12546.1 - 0.093 12.5 0.4 0.64 9.8 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase PRK PF00485.13 CEH12546.1 - 0.098 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 CEH12546.1 - 0.11 12.9 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 CEH12546.1 - 0.14 12.1 0.0 8.6 6.3 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase KTI12 PF08433.5 CEH12546.1 - 0.17 11.0 0.0 5.7 6.0 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Glyco_hydro_42 PF02449.10 CEH12547.1 - 2.2e-77 260.7 3.2 3.2e-77 260.1 2.2 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.5 CEH12547.1 - 4e-30 104.5 0.0 6.6e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain LamB_YcsF PF03746.11 CEH12547.1 - 0.067 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 LamB/YcsF family IncA PF04156.9 CEH12550.1 - 0.00028 20.5 47.2 0.0004 20.0 10.5 17.8 2 1 14 17 17 17 5 IncA protein CENP-F_leu_zip PF10473.4 CEH12550.1 - 0.00032 20.5 46.6 0.0012 18.7 10.9 19.2 4 3 13 20 20 20 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CEH12550.1 - 0.0011 18.1 4.2 0.0011 18.1 2.9 14.6 3 3 13 16 16 16 6 Reovirus sigma C capsid protein Serglycin PF04360.7 CEH12550.1 - 0.19 11.4 4.8 11 5.7 0.1 3.4 3 0 0 3 3 3 0 Serglycin BCDHK_Adom3 PF10436.4 CEH12551.1 - 4.6e-21 75.0 0.0 6.3e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CEH12551.1 - 1.1e-14 54.0 0.0 1.7e-11 43.7 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CEH12551.1 - 1.9e-06 27.5 0.0 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAR1 PF03101.10 CEH12552.1 - 5.8e-07 29.9 1.3 2.2e-06 28.0 0.9 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain PgaD PF13994.1 CEH12553.1 - 0.01 15.2 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 0 PgaD-like protein DUF904 PF06005.7 CEH12553.1 - 0.016 15.5 2.0 0.029 14.6 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) AftA_N PF12250.3 CEH12553.1 - 0.058 12.1 0.1 0.079 11.6 0.1 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal CCDC155 PF14662.1 CEH12553.1 - 0.087 12.4 4.4 0.11 12.0 3.0 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Baculo_11_kDa PF06143.6 CEH12553.1 - 0.12 11.7 1.0 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family CcmD PF04995.9 CEH12553.1 - 0.15 11.7 1.4 0.38 10.5 1.0 1.7 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) Shugoshin_N PF07558.6 CEH12553.1 - 0.52 10.0 3.6 0.82 9.4 2.5 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.10 CEH12553.1 - 0.55 9.7 5.7 5.5 6.5 4.0 2.2 1 1 0 1 1 1 0 Septum formation initiator DUF724 PF05266.9 CEH12553.1 - 5.1 6.6 7.0 0.92 9.0 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) UxaC PF02614.9 CEH12556.1 - 0.0025 16.4 1.0 0.0029 16.3 0.7 1.0 1 0 0 1 1 1 1 Glucuronate isomerase PA28_beta PF02252.13 CEH12556.1 - 0.041 13.3 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit Use1 PF09753.4 CEH12556.1 - 0.17 11.2 4.4 0.21 11.0 3.0 1.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 ADSL_C PF10397.4 CEH12557.1 - 1.9e-15 56.6 0.0 4.8e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Lyase_1 PF00206.15 CEH12557.1 - 6.3e-08 32.1 0.0 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Lyase DUF4089 PF13318.1 CEH12557.1 - 0.088 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) Y_phosphatase2 PF03162.8 CEH12559.1 - 3.3e-51 172.9 0.0 3.9e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CEH12559.1 - 0.00028 21.1 0.0 0.00051 20.3 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CEH12559.1 - 0.043 13.1 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 CEH12559.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.3 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF2201_N PF13203.1 CEH12560.1 - 0.72 8.9 7.8 1 8.4 5.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain NOA36 PF06524.7 CEH12560.1 - 3.4 6.8 5.8 5.1 6.2 4.0 1.3 1 0 0 1 1 1 0 NOA36 protein Pex14_N PF04695.8 CEH12560.1 - 6.4 6.8 10.7 2.3 8.2 5.4 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MPC PF03650.8 CEH12561.1 - 2.8e-33 114.4 0.4 3.4e-33 114.1 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Peptidase_M50 PF02163.17 CEH12561.1 - 0.0083 15.0 0.2 0.009 14.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M50 DNA_primase_S PF01896.14 CEH12563.1 - 5.5e-52 175.4 0.0 9.9e-52 174.6 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit RasGEF PF00617.14 CEH12563.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 RasGEF domain DS PF01916.12 CEH12564.1 - 3e-134 446.8 0.0 3.5e-134 446.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Utp12 PF04003.7 CEH12567.1 - 0.022 14.6 0.9 0.032 14.1 0.6 1.2 1 0 0 1 1 1 0 Dip2/Utp12 Family 60KD_IMP PF02096.15 CEH12567.1 - 0.024 14.2 0.6 0.029 14.0 0.4 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein Cas_Csy2 PF09614.5 CEH12567.1 - 0.057 12.6 0.8 0.075 12.2 0.3 1.2 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) PBP1_TM PF14812.1 CEH12568.1 - 0.47 10.8 1.9 0.56 10.5 1.3 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 CEH12568.1 - 1.6 6.5 4.4 1.5 6.6 3.0 1.0 1 0 0 1 1 1 0 Nop14-like family Apolipoprotein PF01442.13 CEH12569.1 - 0.03 13.8 3.5 0.036 13.5 2.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.7 CEH12569.1 - 0.094 12.5 2.8 1.1 9.0 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.6 CEH12569.1 - 0.97 8.6 8.7 1 8.5 4.3 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase COG2 PF06148.6 CEH12569.1 - 1.8 8.4 5.6 0.87 9.4 1.6 2.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MFS_1 PF07690.11 CEH12570.1 - 2.4e-21 75.8 43.7 3.3e-19 68.8 29.1 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 CEH12572.1 - 2.7e-22 78.9 24.7 2.7e-22 78.9 17.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_M50 PF02163.17 CEH12572.1 - 0.11 11.4 2.4 0.31 9.9 1.3 2.0 1 1 1 2 2 2 0 Peptidase family M50 DUF2945 PF11160.3 CEH12575.1 - 3.2e-14 52.4 0.5 1.3e-13 50.5 0.4 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) Macoilin PF09726.4 CEH12575.1 - 2.6 6.2 27.0 3.7 5.7 18.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Reo_sigmaC PF04582.7 CEH12576.1 - 0.0044 16.2 0.4 0.0044 16.2 0.3 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 CEH12576.1 - 0.54 10.0 5.0 9 6.1 1.9 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.8 CEH12576.1 - 0.85 9.4 8.4 23 4.8 0.6 3.9 3 1 1 4 4 4 0 Lipoprotein leucine-zipper DUF2721 PF11026.3 CEH12576.1 - 0.96 9.0 6.4 8.6 6.0 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Abhydrolase_5 PF12695.2 CEH12578.1 - 2.2e-05 24.2 0.1 0.00021 21.0 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH12578.1 - 0.0008 19.3 0.3 0.0017 18.2 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CEH12578.1 - 0.0027 17.3 0.0 0.006 16.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 CEH12578.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 CEH12578.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme HIT PF01230.18 CEH12579.1 - 0.009 16.5 0.1 0.013 16.0 0.0 1.3 1 1 0 1 1 1 1 HIT domain Sld5 PF05916.6 CEH12582.1 - 7.5e-05 22.9 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein MFS_1 PF07690.11 CEH12583.1 - 4.9e-36 124.1 30.1 4.9e-36 124.1 20.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CEH12583.1 - 2.2e-10 39.3 5.9 2.2e-10 39.3 4.1 2.1 1 1 2 3 3 3 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.7 CEH12583.1 - 0.00076 17.9 0.5 0.0013 17.2 0.3 1.3 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF2423 PF10338.4 CEH12585.1 - 3e-10 39.9 4.9 7.4e-10 38.6 3.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) DUF4451 PF14616.1 CEH12586.1 - 1.1e-17 63.9 0.7 2.1e-17 63.0 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Response_reg PF00072.19 CEH12587.1 - 1.3e-21 76.6 0.0 1.2e-15 57.4 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain NifU_N PF01592.11 CEH12589.1 - 3.1e-50 169.3 0.0 4.7e-50 168.7 0.0 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain Sugar_tr PF00083.19 CEH12590.1 - 3.5e-19 68.7 22.5 1.9e-18 66.3 15.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Lactamase_B_2 PF12706.2 CEH12591.1 - 7.9e-27 94.0 0.1 2e-26 92.7 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CEH12591.1 - 4.1e-07 29.3 0.0 1.5e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 CEH12591.1 - 0.026 14.1 0.3 0.21 11.2 0.2 2.3 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily PALP PF00291.20 CEH12592.1 - 5.1e-51 173.7 0.1 1.1e-50 172.6 0.1 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF755 PF05501.6 CEH12592.1 - 0.092 12.8 3.6 0.43 10.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) RELT PF12606.3 CEH12592.1 - 0.17 11.0 0.0 0.4 9.8 0.0 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 LSM PF01423.17 CEH12593.1 - 2.9e-12 45.9 0.0 4.5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CEH12593.1 - 0.0002 21.2 0.3 0.00049 19.9 0.2 1.6 1 1 1 2 2 2 1 Ataxin 2 SM domain Gemin7 PF11095.3 CEH12593.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) FUSC_2 PF13515.1 CEH12594.1 - 6.1e-14 52.0 14.1 6.1e-14 52.0 9.8 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 CEH12594.1 - 2.3e-11 42.9 18.3 2.3e-11 42.9 12.7 3.6 3 2 0 4 4 4 2 Fusaric acid resistance protein family ALMT PF11744.3 CEH12594.1 - 1.8e-09 36.7 4.8 2.6e-07 29.6 2.8 3.2 3 0 0 3 3 3 1 Aluminium activated malate transporter DUF2422 PF10337.4 CEH12594.1 - 1.4e-08 33.9 3.8 1.4e-08 33.9 2.6 4.3 4 1 0 4 4 4 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 CEH12594.1 - 2.9e-06 27.0 1.4 8.3e-06 25.5 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 CEH12594.1 - 4e-05 23.5 2.8 0.00011 22.0 1.9 1.8 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF939) Asparaginase PF00710.15 CEH12595.1 - 2.8e-64 216.9 0.5 3.1e-64 216.8 0.3 1.0 1 0 0 1 1 1 1 Asparaginase DUF3372 PF11852.3 CEH12595.1 - 0.07 12.2 0.6 0.18 10.9 0.0 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3372) AA_permease PF00324.16 CEH12596.1 - 5.2e-109 364.7 33.1 6.3e-109 364.4 23.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEH12596.1 - 5.3e-32 110.8 36.8 7.5e-32 110.4 25.5 1.2 1 0 0 1 1 1 1 Amino acid permease Pro-kuma_activ PF09286.6 CEH12597.1 - 3.9e-44 150.1 1.0 7.6e-44 149.2 0.4 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CEH12597.1 - 2.1e-06 27.0 2.0 4e-06 26.1 1.4 1.4 1 0 0 1 1 1 1 Subtilase family DUF1770 PF08589.5 CEH12598.1 - 7.1e-06 26.5 0.4 1.2e-05 25.7 0.2 1.5 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) DUF3835 PF12927.2 CEH12599.1 - 1e-05 26.4 0.3 0.02 15.8 0.0 3.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3835) Methyltransf_4 PF02390.12 CEH12600.1 - 4.2e-48 163.0 0.0 1.4e-36 125.3 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CEH12600.1 - 4e-05 24.1 0.0 0.00072 20.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH12600.1 - 0.00034 20.6 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH12600.1 - 0.0017 17.9 0.0 0.041 13.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH12600.1 - 0.004 17.5 0.0 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH12600.1 - 0.0043 17.4 0.0 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH12600.1 - 0.0074 16.7 0.0 0.88 10.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 CEH12600.1 - 0.016 14.5 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 CEH12600.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CEH12600.1 - 0.11 11.9 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain RNA_pol_Rpb4 PF03874.11 CEH12601.1 - 6e-12 45.6 1.4 3.3e-11 43.2 1.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb4 MRP-L47 PF06984.8 CEH12602.1 - 2.6e-15 56.0 1.3 4.2e-15 55.4 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) E2R135 PF11570.3 CEH12602.1 - 0.089 12.8 5.7 0.13 12.3 4.0 1.3 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Macoilin PF09726.4 CEH12604.1 - 0.00027 19.3 23.1 0.00033 19.1 16.0 1.1 1 0 0 1 1 1 1 Transmembrane protein TPR_MLP1_2 PF07926.7 CEH12604.1 - 0.0012 18.6 19.2 0.0012 18.6 13.3 3.0 2 1 1 3 3 2 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 CEH12604.1 - 0.0057 16.2 14.5 0.0057 16.2 10.0 3.3 1 1 1 2 2 2 1 IncA protein MAD PF05557.8 CEH12604.1 - 0.026 12.6 38.3 0.091 10.8 10.6 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF812 PF05667.6 CEH12604.1 - 0.69 8.3 29.0 0.83 8.0 19.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 CEH12604.1 - 0.84 8.7 3.7 1.3 8.1 0.1 2.8 2 1 0 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CEH12604.1 - 0.86 7.9 27.2 0.66 8.3 17.5 1.6 1 1 1 2 2 2 0 AAA domain His_kinase PF06580.8 CEH12604.1 - 0.99 9.3 6.3 1.1 9.1 0.4 3.4 3 1 1 4 4 4 0 Histidine kinase bZIP_1 PF00170.16 CEH12604.1 - 1.7 8.6 20.1 0.43 10.5 0.1 4.1 3 1 0 3 3 3 0 bZIP transcription factor ATG16 PF08614.6 CEH12604.1 - 1.9 8.2 41.0 0.051 13.3 7.5 3.5 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Streptin-Immun PF11083.3 CEH12604.1 - 2.3 8.2 12.4 3.5 7.6 4.7 3.0 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein BLOC1_2 PF10046.4 CEH12604.1 - 3.3 7.9 18.6 0.038 14.1 2.9 3.5 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 CEH12604.1 - 3.4 6.2 36.2 0.082 11.5 10.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.3 CEH12604.1 - 3.5 7.5 40.9 0.73 9.7 6.7 4.0 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding AbiH PF14253.1 CEH12604.1 - 3.9 6.9 17.7 1.6 8.2 6.1 2.2 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH HAP1_N PF04849.8 CEH12604.1 - 8 5.3 36.4 0.7 8.7 16.7 2.8 1 1 2 3 3 3 0 HAP1 N-terminal conserved region Retrotrans_gag PF03732.12 CEH12605.1 - 1.6e-05 24.8 0.0 4.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein FliJ PF02050.11 CEH12605.1 - 0.0069 16.4 0.1 4 7.5 0.0 2.3 2 0 0 2 2 2 2 Flagellar FliJ protein RVT_1 PF00078.22 CEH12606.1 - 2.1e-12 46.8 0.0 4.3e-12 45.8 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1413 PF07205.6 CEH12606.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) rve PF00665.21 CEH12607.1 - 1e-18 67.5 0.0 5.9e-18 65.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CEH12607.1 - 9.3e-07 28.4 0.1 2.1e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DnaJ-X PF14308.1 CEH12611.1 - 1.6e-46 158.1 6.7 1.6e-46 158.1 4.6 2.0 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CEH12611.1 - 3.3e-26 90.8 0.4 3.3e-26 90.8 0.3 2.5 2 0 0 2 2 2 1 DnaJ domain IBR PF01485.16 CEH12611.1 - 0.069 13.0 0.7 0.14 12.0 0.5 1.5 1 0 0 1 1 1 0 IBR domain Ubiq_cyt_C_chap PF03981.7 CEH12611.1 - 0.24 11.2 3.7 3.1 7.6 0.1 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone DUF4187 PF13821.1 CEH12612.1 - 9.7e-16 57.1 1.1 9.7e-16 57.1 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 CEH12612.1 - 3.8e-05 23.3 0.7 3.8e-05 23.3 0.5 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CEH12612.1 - 1.9 8.4 6.0 0.38 10.6 0.2 2.4 2 0 0 2 2 2 0 DExH-box splicing factor binding site Ribosomal_60s PF00428.14 CEH12612.1 - 6.2 7.2 10.4 2.9 8.3 3.3 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein SAM_PNT PF02198.11 CEH12613.1 - 0.043 13.5 0.0 0.076 12.7 0.0 1.4 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF3439 PF11921.3 CEH12617.1 - 0.7 9.6 8.2 7.1 6.4 3.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) NAD_binding_7 PF13241.1 CEH12619.1 - 3.8e-28 97.7 0.0 6.1e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CEH12619.1 - 4.5e-20 70.7 0.1 7.7e-20 69.9 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CEH12619.1 - 5.6e-09 34.8 0.3 1.3e-08 33.6 0.2 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SH2_2 PF14633.1 CEH12620.1 - 5.8e-65 218.4 0.0 5.8e-65 218.4 0.0 2.1 2 0 0 2 2 2 1 SH2 domain SPT6_acidic PF14632.1 CEH12620.1 - 1.8e-20 72.9 37.7 1.8e-20 72.9 26.1 7.0 5 2 2 7 7 7 2 Acidic N-terminal SPT6 YqgF PF14639.1 CEH12620.1 - 6.9e-20 71.1 0.0 1.5e-18 66.7 0.0 2.5 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 CEH12620.1 - 1.7e-17 63.5 0.1 1.7e-17 63.5 0.0 3.7 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 CEH12620.1 - 6e-15 55.2 0.0 1.4e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 CEH12620.1 - 0.00013 21.8 0.0 0.00042 20.2 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.18 CEH12620.1 - 0.00059 19.8 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 S1 RNA binding domain ALS_ss_C PF10369.4 CEH12620.1 - 0.019 14.6 0.0 0.061 13.0 0.0 1.9 1 0 0 1 1 1 0 Small subunit of acetolactate synthase Ras PF00071.17 CEH12621.1 - 1.8e-24 85.9 0.0 2e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH12621.1 - 1.7e-06 28.5 0.0 2.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH12621.1 - 4.7e-05 22.6 0.0 5.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEH12621.1 - 0.007 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 CEH12621.1 - 0.034 14.4 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 CEH12621.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin RRM_1 PF00076.17 CEH12622.1 - 6.5e-17 60.9 0.0 1e-07 31.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH12622.1 - 5.9e-14 51.7 0.0 4.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH12622.1 - 8.3e-05 22.3 0.0 0.013 15.3 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEH12622.1 - 0.14 12.0 0.0 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Abhydrolase_6 PF12697.2 CEH12623.1 - 0.0016 18.4 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH12623.1 - 0.0051 16.5 0.6 0.0087 15.8 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family CbiK PF06180.6 CEH12623.1 - 0.0096 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Lyase_aromatic PF00221.14 CEH12625.1 - 4.2e-126 421.1 0.9 4.2e-126 421.1 0.6 1.9 1 1 1 2 2 2 1 Aromatic amino acid lyase Abhydrolase_6 PF12697.2 CEH12626.1 - 6e-21 75.3 2.8 1.2e-20 74.3 1.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH12626.1 - 2.8e-06 27.1 0.3 1.3e-05 24.9 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH12626.1 - 2e-05 24.2 0.0 0.011 15.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.15 CEH12626.1 - 0.008 15.6 0.0 0.008 15.6 0.0 1.6 2 0 0 2 2 2 1 Putative esterase AMP-binding PF00501.23 CEH12627.1 - 2e-21 75.8 0.3 3.4e-21 75.1 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PI3_PI4_kinase PF00454.22 CEH12628.1 - 5.1e-51 173.4 0.0 8.9e-51 172.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 CEH12628.1 - 2.6e-21 75.5 0.0 1.6e-20 73.0 0.0 2.5 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.18 CEH12628.1 - 1.8e-16 60.0 4.8 3.4e-16 59.1 3.3 1.3 1 0 0 1 1 1 1 FAT domain FATC PF02260.15 CEH12628.1 - 2.6e-08 33.1 0.0 6.5e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 FATC domain Pro_isomerase PF00160.16 CEH12631.1 - 6e-44 149.9 0.4 9.2e-44 149.3 0.3 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CEH12631.1 - 7.4e-07 28.7 2.6 0.00031 20.3 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CEH12631.1 - 4.6e-05 23.0 4.4 0.013 15.3 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEH12631.1 - 0.00015 21.1 2.1 0.3 10.7 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH12631.1 - 0.79 10.5 4.7 14 6.6 1.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEH12632.1 - 3.5e-23 81.0 4.3 6.2e-14 51.3 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CEH12632.1 - 6.4e-22 76.2 0.6 7.3e-10 38.0 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEH12632.1 - 1.6e-18 65.0 0.6 1.6e-07 30.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CEH12632.1 - 3.7e-12 45.0 1.2 0.00082 18.9 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CEH12632.1 - 1.9e-11 43.2 0.2 0.00013 21.8 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEH12632.1 - 1.7e-09 38.0 4.7 6.5e-06 26.6 0.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH12632.1 - 2.1e-09 37.1 1.8 0.014 15.9 0.0 4.1 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEH12632.1 - 3.2e-09 35.8 0.1 5.7e-05 22.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEH12632.1 - 2.3e-07 31.0 2.1 0.0053 17.0 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEH12632.1 - 1.2e-06 28.3 1.5 1.1e-05 25.2 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 CEH12632.1 - 8.8e-05 21.6 0.5 0.002 17.2 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CEH12632.1 - 0.00072 19.3 0.0 0.1 12.4 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEH12632.1 - 0.0026 18.1 1.1 3.7 8.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CEH12632.1 - 0.016 15.3 1.4 0.097 12.8 0.9 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.7 CEH12632.1 - 0.068 12.7 0.4 0.67 9.5 0.0 2.3 1 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.13 CEH12632.1 - 0.19 11.6 1.5 9.2 6.2 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 CEH12633.1 - 4.4e-36 122.5 35.4 1.3e-07 32.0 0.9 8.7 9 0 0 9 9 9 7 Sel1 repeat TPR_6 PF13174.1 CEH12633.1 - 0.0055 17.0 6.3 0.049 14.1 0.0 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat IF-2B PF01008.12 CEH12634.1 - 5.6e-61 206.0 0.0 1e-60 205.1 0.0 1.4 2 0 0 2 2 2 1 Initiation factor 2 subunit family SR-25 PF10500.4 CEH12634.1 - 0.81 9.1 12.1 1.3 8.4 8.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rotamase_2 PF13145.1 CEH12634.1 - 2.6 8.6 10.0 4.9 7.7 6.9 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain Rtf2 PF04641.7 CEH12634.1 - 4.2 6.5 6.1 6.1 5.9 4.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger E1-N PF14463.1 CEH12635.1 - 0.044 13.3 1.4 0.077 12.5 1.0 1.4 1 0 0 1 1 1 0 E1 N-terminal domain HTH_3 PF01381.17 CEH12636.1 - 5.8e-12 45.2 0.5 1e-11 44.4 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 CEH12636.1 - 7e-08 32.3 0.2 1.5e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_19 PF12844.2 CEH12636.1 - 0.00023 21.1 0.1 0.00033 20.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 CEH12636.1 - 0.0019 18.3 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain I-set PF07679.11 CEH12638.1 - 0.082 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Leader_Trp PF08255.6 CEH12643.1 - 0.33 10.6 2.5 0.37 10.5 0.5 2.0 2 0 0 2 2 2 0 Trp-operon Leader Peptide RTX PF02382.10 CEH12650.1 - 0.081 11.1 0.0 0.084 11.1 0.0 1.1 1 0 0 1 1 1 0 RTX N-terminal domain CLAG PF03805.8 CEH12650.1 - 0.19 9.0 0.1 0.23 8.7 0.1 1.0 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein Methyltransf_18 PF12847.2 CEH12652.1 - 1.1e-05 25.9 0.0 1.8e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH12652.1 - 9.4e-05 22.0 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH12652.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PWI PF01480.12 CEH12653.1 - 2.7e-26 91.4 0.0 3.9e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 PWI domain Fer2_3 PF13085.1 CEH12654.1 - 1.4e-31 108.5 0.0 2.5e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CEH12654.1 - 2.5e-09 37.3 6.4 2.5e-09 37.3 4.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CEH12654.1 - 1e-08 35.0 4.6 1e-08 35.0 3.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CEH12654.1 - 1.9e-05 24.9 1.5 1.9e-05 24.9 1.1 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CEH12654.1 - 9.9e-05 22.5 2.9 0.067 13.4 0.1 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CEH12654.1 - 0.00015 21.4 4.5 0.00015 21.4 3.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CEH12654.1 - 0.00026 21.2 2.8 0.00026 21.2 2.0 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CEH12654.1 - 0.012 15.3 1.0 0.012 15.3 0.7 2.1 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 CEH12654.1 - 0.32 11.6 4.0 1.3 9.6 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain WD40 PF00400.27 CEH12655.1 - 9.6e-19 66.5 14.0 0.0016 18.2 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 CEH12655.1 - 5e-12 45.6 0.0 9.5e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain FGF-BP1 PF06473.7 CEH12656.1 - 6.1 6.3 6.8 1.4 8.4 1.7 2.0 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) VanZ PF04892.7 CEH12657.1 - 6.2e-09 35.9 0.5 1.2e-08 35.0 0.4 1.4 1 0 0 1 1 1 1 VanZ like family DUF1275 PF06912.6 CEH12657.1 - 0.016 14.4 1.2 0.023 13.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) BTV_NS2 PF04514.7 CEH12657.1 - 0.06 12.2 2.3 0.086 11.7 1.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TauE PF01925.14 CEH12657.1 - 0.19 11.1 2.5 0.39 10.1 1.9 1.4 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Acyl_transf_3 PF01757.17 CEH12657.1 - 0.33 9.7 5.9 0.8 8.4 4.1 1.4 1 1 0 1 1 1 0 Acyltransferase family Peptidase_M28 PF04389.12 CEH12658.1 - 2.9e-33 115.0 0.0 4.5e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CEH12658.1 - 1e-14 54.0 0.8 1.9e-14 53.1 0.5 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 CEH12658.1 - 0.00065 19.2 0.0 0.0012 18.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 VPS9 PF02204.13 CEH12659.1 - 8.6e-29 99.6 0.0 1.4e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 CEH12659.1 - 4.7e-09 35.5 0.0 1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 CEH12659.1 - 2.1e-06 27.4 0.0 4.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 DMRTA motif SYF2 PF08231.7 CEH12660.1 - 2.7e-38 131.5 6.3 2.7e-38 131.5 4.4 2.0 2 0 0 2 2 2 1 SYF2 splicing factor Annexin PF00191.15 CEH12661.1 - 6.9e-51 170.0 0.3 8.9e-15 54.3 0.0 4.5 4 1 0 4 4 4 4 Annexin DUF1168 PF06658.7 CEH12663.1 - 1.6e-37 128.1 17.0 2.8e-37 127.4 11.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) CAML PF14963.1 CEH12663.1 - 5.7 6.2 8.4 9.2 5.5 5.8 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Menin PF05053.8 CEH12663.1 - 9.5 4.2 10.2 14 3.7 7.0 1.3 1 1 0 1 1 1 0 Menin DUF4098 PF13345.1 CEH12664.1 - 9.4e-06 25.4 6.0 0.0042 17.0 0.1 3.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4098) Arf PF00025.16 CEH12666.1 - 8.3e-74 246.5 0.1 9e-74 246.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CEH12666.1 - 5.5e-14 51.6 0.6 9.4e-10 37.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CEH12666.1 - 1.1e-13 50.8 0.0 1.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CEH12666.1 - 1.7e-13 50.2 0.0 1.9e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CEH12666.1 - 1.2e-11 44.2 0.0 1.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CEH12666.1 - 1.1e-07 32.3 0.0 1.5e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CEH12666.1 - 2e-05 24.5 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEH12666.1 - 0.0031 16.9 0.2 0.025 13.9 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CEH12666.1 - 0.012 14.8 0.5 0.032 13.4 0.3 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 CEH12666.1 - 0.019 14.6 0.5 0.045 13.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ArgK PF03308.11 CEH12666.1 - 0.061 12.0 0.6 0.67 8.6 0.0 2.3 2 1 1 3 3 3 0 ArgK protein WD40 PF00400.27 CEH12667.1 - 3.6e-11 42.4 4.0 3.6e-05 23.4 0.3 4.8 4 1 0 4 4 4 4 WD domain, G-beta repeat PPR_2 PF13041.1 CEH12668.1 - 2.6e-27 94.5 0.0 2.1e-07 30.8 0.0 6.5 3 1 4 7 7 7 5 PPR repeat family PPR PF01535.15 CEH12668.1 - 2.9e-20 70.7 4.0 0.0016 18.2 0.0 8.7 9 0 0 9 9 9 6 PPR repeat PPR_3 PF13812.1 CEH12668.1 - 5.4e-20 69.9 6.3 6.1e-05 22.9 0.0 8.9 9 0 0 9 9 9 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 CEH12668.1 - 1.1e-17 63.2 0.0 0.0008 18.8 0.0 6.2 6 0 0 6 6 6 4 PPR repeat Sec7 PF01369.15 CEH12669.1 - 4.9e-32 111.1 0.0 8.8e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 CEH12669.1 - 9.6e-26 90.2 0.0 2.1e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Response_reg PF00072.19 CEH12670.1 - 7.6e-18 64.5 2.0 8.5e-18 64.4 0.0 2.2 3 0 0 3 3 3 1 Response regulator receiver domain HATPase_c PF02518.21 CEH12670.1 - 3e-12 46.2 1.0 9.8e-12 44.5 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 CEH12670.1 - 5.1e-11 42.3 0.8 2e-10 40.5 0.4 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Longin PF13774.1 CEH12671.1 - 4.9e-22 77.2 0.0 7.4e-22 76.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CEH12671.1 - 2.5e-15 55.8 0.1 4.6e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Synaptobrevin ANTH PF07651.11 CEH12672.1 - 1.3e-72 243.9 0.0 6e-72 241.6 0.0 2.2 1 0 0 1 1 1 1 ANTH domain I_LWEQ PF01608.12 CEH12672.1 - 6.6e-64 214.4 10.0 6.6e-64 214.4 7.0 4.6 5 1 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 CEH12672.1 - 1.3e-07 31.4 0.0 1.1e-06 28.4 0.0 2.7 2 0 0 2 2 2 1 ENTH domain TcdB_N PF12918.2 CEH12672.1 - 0.0082 16.1 0.3 0.026 14.6 0.2 1.9 1 0 0 1 1 1 1 TcdB toxin N-terminal helical domain WD40_alt PF14077.1 CEH12672.1 - 0.093 12.3 0.5 2.6 7.7 0.0 3.3 3 0 0 3 3 3 0 Alternative WD40 repeat motif Med15_fungi PF05397.7 CEH12674.1 - 7.5e-22 77.4 0.1 7.5e-22 77.4 0.1 3.1 3 0 0 3 3 3 1 Mediator complex subunit 15 ARID PF01388.16 CEH12674.1 - 8e-15 54.4 0.0 3.6e-14 52.3 0.0 2.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF1127 PF06568.6 CEH12674.1 - 0.097 12.1 0.0 1.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) ABC2_membrane PF01061.19 CEH12676.1 - 2.9e-33 114.8 16.5 2.9e-33 114.8 11.4 2.1 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 CEH12676.1 - 1.2e-22 80.6 0.0 2.1e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CEH12676.1 - 5.2e-07 29.9 0.2 0.0028 17.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CEH12676.1 - 1.7e-05 24.8 0.2 6.1e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CEH12676.1 - 0.00012 21.5 0.3 0.00026 20.4 0.2 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CEH12676.1 - 0.0018 17.4 0.0 0.0036 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 CEH12676.1 - 0.0084 16.0 0.3 0.047 13.6 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 CEH12676.1 - 0.022 14.2 0.2 0.061 12.8 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 CEH12676.1 - 0.22 10.4 27.8 0.012 14.6 15.3 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein ubiquitin PF00240.18 CEH12677.1 - 0.0031 16.8 0.0 0.0058 16.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 CEH12677.1 - 0.0037 17.1 0.0 0.0088 15.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CEH12677.1 - 0.0048 17.0 0.0 0.02 15.0 0.0 2.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Flg_hook PF02120.11 CEH12677.1 - 0.046 13.3 1.0 1.5 8.4 0.0 2.7 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK DUF4413 PF14372.1 CEH12677.1 - 0.18 11.7 0.1 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) DASH_Spc19 PF08287.6 CEH12678.1 - 2.3e-25 88.9 7.6 3e-25 88.6 5.3 1.1 1 0 0 1 1 1 1 Spc19 Seryl_tRNA_N PF02403.17 CEH12678.1 - 0.027 14.4 6.8 0.41 10.6 0.2 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ax_dynein_light PF10211.4 CEH12678.1 - 0.071 12.9 4.7 0.1 12.3 3.2 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Peroxidase_2 PF01328.12 CEH12678.1 - 0.094 11.3 0.1 0.18 10.4 0.0 1.4 1 1 0 1 1 1 0 Peroxidase, family 2 AKNA PF12443.3 CEH12678.1 - 0.33 11.0 3.3 0.57 10.2 1.9 1.7 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF1843 PF08898.5 CEH12678.1 - 0.33 11.0 0.1 0.33 11.0 0.0 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF1843) Lge1 PF11488.3 CEH12678.1 - 0.71 10.1 7.7 1.1 9.4 4.6 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 COG5 PF10392.4 CEH12678.1 - 1.8 8.5 10.1 12 5.9 0.5 3.1 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Nup54 PF13874.1 CEH12678.1 - 3.5 7.2 10.2 6.4 6.4 7.0 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 FAD-SLDH PF12318.3 CEH12678.1 - 8.9 5.9 7.3 4.6 6.9 2.0 2.3 1 1 2 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Bromodomain PF00439.20 CEH12679.1 - 1.5e-19 69.6 0.0 2.7e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF2404 PF10296.4 CEH12681.1 - 0.0029 17.7 0.0 0.0072 16.4 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) IGR PF09597.5 CEH12682.1 - 0.00018 21.3 0.0 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 1 IGR protein motif Ank PF00023.25 CEH12683.1 - 7.2e-37 123.3 1.4 8.5e-09 34.7 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 CEH12683.1 - 3.3e-30 104.2 0.9 1.6e-13 50.7 0.0 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CEH12683.1 - 1.7e-27 92.7 1.1 1.3e-05 24.9 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 CEH12683.1 - 5.7e-26 89.9 2.3 1.3e-07 31.5 0.1 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEH12683.1 - 9.6e-23 80.1 2.5 1.3e-06 28.6 0.1 5.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) DUF3459 PF11941.3 CEH12683.1 - 0.038 14.1 0.5 0.1 12.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) DUF4301 PF14134.1 CEH12683.1 - 0.11 11.0 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) DIM1 PF02966.11 CEH12684.1 - 2.9e-66 221.0 0.0 3.3e-66 220.8 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CEH12684.1 - 0.044 13.4 0.1 0.053 13.2 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin Urm1 PF09138.6 CEH12685.1 - 1.5e-24 85.9 0.0 1.5e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CEH12685.1 - 0.0014 18.9 0.0 0.0027 18.0 0.0 1.5 1 0 0 1 1 1 1 ThiS family PhnA PF03831.9 CEH12685.1 - 0.091 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 PhnA protein MRP-L20 PF12824.2 CEH12689.1 - 2e-31 109.1 4.7 3.7e-31 108.3 3.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Pyr_redox_2 PF07992.9 CEH12689.1 - 9.6e-05 22.3 0.0 0.0021 17.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HTH_11 PF08279.7 CEH12689.1 - 0.0087 15.6 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 HTH domain Neugrin PF06413.6 CEH12689.1 - 0.025 14.3 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 Neugrin ThiF PF00899.16 CEH12689.1 - 0.23 11.2 0.1 0.43 10.4 0.1 1.4 1 0 0 1 1 1 0 ThiF family DcpS_C PF11969.3 CEH12690.1 - 2.3e-14 53.6 3.1 4.5e-14 52.6 0.3 2.2 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CEH12690.1 - 5.6e-11 42.8 0.3 1.1e-05 25.8 0.1 2.3 2 0 0 2 2 2 2 HIT domain Alginate_lyase PF05426.7 CEH12691.1 - 1.1e-53 182.3 3.4 7.2e-53 179.6 0.6 2.1 2 0 0 2 2 2 2 Alginate lyase Ank PF00023.25 CEH12692.1 - 5.1e-20 70.2 5.4 1.4e-06 27.7 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 CEH12692.1 - 4.1e-18 65.5 0.1 4.1e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEH12692.1 - 9.5e-15 54.2 2.9 1.3e-07 31.6 0.0 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH12692.1 - 1.5e-13 49.5 3.6 0.0022 18.0 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CEH12692.1 - 1.5e-13 50.8 1.1 5.7e-11 42.6 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Prenyltrans_1 PF13243.1 CEH12692.1 - 0.078 13.0 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Prenyltransferase-like Doppel PF11466.3 CEH12693.1 - 0.51 9.9 3.9 0.44 10.1 1.2 2.1 2 0 0 2 2 2 0 Prion-like protein Doppel zf-H2C2_2 PF13465.1 CEH12694.1 - 1e-09 38.1 21.0 3.6e-06 27.0 3.8 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CEH12694.1 - 7.1e-08 32.3 13.6 0.0017 18.6 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH12694.1 - 0.0088 16.3 2.2 0.0088 16.3 1.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger Tom22 PF04281.8 CEH12694.1 - 0.52 9.8 2.9 1.1 8.7 2.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TFIIA PF03153.8 CEH12695.1 - 1.9e-46 159.6 24.5 1.4e-28 100.8 8.5 2.8 2 1 1 3 3 3 2 Transcription factor IIA, alpha/beta subunit YL1_C PF08265.6 CEH12695.1 - 3.4e-16 58.4 0.1 5.6e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain TRAM_LAG1_CLN8 PF03798.11 CEH12698.1 - 1.5e-07 31.1 14.3 2.1e-07 30.6 9.9 1.2 1 0 0 1 1 1 1 TLC domain adh_short PF00106.20 CEH12699.1 - 3.8e-14 52.9 1.9 1.9e-13 50.7 0.2 2.6 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CEH12699.1 - 0.00076 19.1 4.3 0.0032 17.1 1.5 2.6 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CEH12699.1 - 0.0014 18.4 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 CEH12699.1 - 0.013 15.4 0.5 0.027 14.4 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.1 CEH12699.1 - 0.038 14.0 0.3 9.2 6.2 0.4 2.3 2 0 0 2 2 2 0 NADH(P)-binding DFP PF04127.10 CEH12699.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein SSF PF00474.12 CEH12701.1 - 4.6e-19 68.3 30.5 4.6e-19 68.3 21.1 1.9 2 0 0 2 2 2 1 Sodium:solute symporter family EIF_2_alpha PF07541.7 CEH12702.1 - 4.2e-41 139.2 0.3 3.3e-40 136.3 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CEH12702.1 - 3.8e-13 49.3 1.0 1e-12 47.9 0.7 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DUF2884 PF11101.3 CEH12702.1 - 0.031 13.6 0.1 4 6.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2884) DUF4312 PF14189.1 CEH12702.1 - 0.12 12.2 1.3 1.7 8.5 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4312) RabGGT_insert PF07711.6 CEH12703.1 - 0.054 13.3 0.0 0.066 13.0 0.0 1.3 1 1 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain RhoGEF PF00621.15 CEH12704.1 - 3e-30 105.4 0.0 4.7e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Transcrip_reg PF01709.15 CEH12706.1 - 3.1e-33 114.8 3.2 2.5e-23 82.4 0.0 3.1 1 1 2 3 3 3 3 Transcriptional regulator DUF2841 PF11001.3 CEH12707.1 - 3.4e-38 130.3 0.3 5.5e-38 129.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) NOB1_Zn_bind PF08772.6 CEH12711.1 - 3.2e-23 81.3 0.7 6e-23 80.4 0.5 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_4 PF13638.1 CEH12711.1 - 0.00063 19.8 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 PIN domain zf-NADH-PPase PF09297.6 CEH12711.1 - 0.12 11.8 4.5 3.7 7.1 0.0 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 CEH12711.1 - 0.28 10.4 5.9 0.52 9.5 4.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain AF1Q PF15017.1 CEH12711.1 - 7.4 6.5 15.2 0.84 9.5 0.8 3.6 3 1 1 4 4 4 0 Drug resistance and apoptosis regulator Sec62 PF03839.11 CEH12712.1 - 4.8e-45 153.7 0.1 7.6e-45 153.0 0.1 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 Glyco_tran_28_C PF04101.11 CEH12713.1 - 1.4e-17 63.8 0.1 7.2e-14 51.7 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase family 28 C-terminal domain MutS_V PF00488.16 CEH12714.1 - 7.5e-90 300.4 0.0 1.6e-89 299.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CEH12714.1 - 6e-35 120.8 1.0 1.3e-34 119.7 0.7 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 CEH12714.1 - 4.8e-19 68.7 0.4 5e-18 65.4 0.0 2.8 4 0 0 4 4 4 1 MutS domain II MutS_IV PF05190.13 CEH12714.1 - 4.7e-17 61.9 0.4 1.1e-16 60.8 0.1 1.9 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 CEH12714.1 - 9.1e-11 41.7 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain I NTPase_1 PF03266.10 CEH12714.1 - 0.079 12.6 0.5 26 4.4 0.0 3.1 3 0 0 3 3 3 0 NTPase Adap_comp_sub PF00928.16 CEH12716.1 - 1.1e-84 283.6 0.0 1.4e-84 283.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CEH12716.1 - 0.00054 19.6 0.5 0.00093 18.9 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 CEH12716.1 - 0.049 13.5 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) Peptidase_M48 PF01435.13 CEH12717.1 - 2.3e-29 102.5 0.1 3.9e-29 101.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 Kelch_2 PF07646.10 CEH12717.1 - 0.074 12.8 0.2 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Kelch motif SPX PF03105.14 CEH12719.1 - 2.4e-33 116.1 5.0 1.3e-21 77.6 0.3 3.3 2 1 1 3 3 3 2 SPX domain DUF953 PF06110.6 CEH12721.1 - 6.8e-10 38.4 0.0 7.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 CEH12721.1 - 1.2e-06 28.0 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CEH12721.1 - 0.0029 17.7 0.0 0.084 12.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CEH12721.1 - 0.0031 17.0 0.0 0.0045 16.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CEH12721.1 - 0.0083 16.3 0.0 0.031 14.4 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain PNRC PF15365.1 CEH12722.1 - 2.7e-06 27.2 0.9 2.7e-06 27.2 0.7 2.9 3 1 0 3 3 3 1 Proline-rich nuclear receptor coactivator Ank_2 PF12796.2 CEH12723.1 - 2.5e-35 120.6 3.6 1.9e-12 47.3 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CEH12723.1 - 2.3e-31 105.9 16.9 4.5e-08 32.5 0.3 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 CEH12723.1 - 2.3e-26 91.6 5.1 3.9e-08 33.5 0.1 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) zf-DHHC PF01529.15 CEH12723.1 - 1.3e-23 83.2 14.6 7.1e-13 48.3 0.3 2.3 2 0 0 2 2 2 2 DHHC palmitoyltransferase Ank_5 PF13857.1 CEH12723.1 - 2.9e-23 81.3 6.9 3.7e-08 33.3 0.2 5.1 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH12723.1 - 2e-19 67.7 6.4 0.00026 20.9 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat PrgI PF12666.2 CEH12723.1 - 0.16 12.1 3.9 0.35 11.0 0.3 2.6 2 0 0 2 2 2 0 PrgI family protein Spb1_C PF07780.7 CEH12725.1 - 3.9e-67 225.8 34.0 3.9e-67 225.8 23.6 3.9 3 2 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 CEH12725.1 - 2e-52 177.8 0.0 3.7e-52 176.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 CEH12725.1 - 2.7e-42 143.9 2.1 2.7e-42 143.9 1.5 6.3 5 2 1 6 6 6 1 Domain of unknown function (DUF3381) SET PF00856.23 CEH12726.1 - 3.2e-08 34.0 0.0 2.3e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 SET domain RecX PF02631.11 CEH12726.1 - 0.076 13.2 0.1 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 RecX family tRNA-synt_1 PF00133.17 CEH12727.1 - 2e-219 729.5 0.0 1.4e-218 726.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CEH12727.1 - 9.2e-24 83.9 0.0 2.2e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CEH12727.1 - 3.9e-19 68.5 0.6 4.3e-07 28.9 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) RPA_C PF08784.6 CEH12728.1 - 3.3e-09 37.0 1.1 3.5e-08 33.7 0.0 2.5 3 0 0 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 CEH12728.1 - 3.8e-09 36.2 0.1 7.8e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain B12D PF06522.6 CEH12729.1 - 3.2e-19 68.3 0.4 3.9e-19 68.1 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit EST1_DNA_bind PF10373.4 CEH12730.1 - 9.1e-36 123.5 0.0 1.8e-35 122.5 0.0 1.5 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CEH12730.1 - 2.8e-07 30.5 0.1 1.1e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 CEH12730.1 - 0.0025 17.4 0.0 0.0086 15.7 0.0 1.9 1 0 0 1 1 1 1 TPR repeat ATP-synt_F PF01990.12 CEH12731.1 - 1.4e-28 99.0 0.0 1.7e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit CTX_RstB PF07459.6 CEH12731.1 - 0.081 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 CTX phage RstB protein EF-hand_1 PF00036.27 CEH12733.1 - 1.2e-25 86.8 13.6 3.1e-09 35.4 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CEH12733.1 - 1.8e-24 85.6 9.3 2.5e-13 49.9 1.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEH12733.1 - 5.7e-24 81.7 10.9 1.7e-08 33.6 0.1 4.9 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 CEH12733.1 - 1.6e-18 66.0 12.6 8.9e-09 34.8 0.9 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CEH12733.1 - 1.7e-18 65.0 10.9 7.6e-06 25.0 0.1 3.9 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CEH12733.1 - 2e-09 37.2 0.3 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CEH12733.1 - 1.4e-07 31.1 0.8 0.00072 19.2 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 CEH12733.1 - 0.0045 16.5 0.1 0.065 12.7 0.0 2.4 2 1 1 3 3 3 1 Caleosin related protein Metal_resist PF13801.1 CEH12733.1 - 0.21 11.5 1.7 0.41 10.6 0.0 2.3 3 0 0 3 3 3 0 Heavy-metal resistance TauD PF02668.11 CEH12734.1 - 1.2e-53 182.4 0.4 1.7e-53 181.9 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GST_N_3 PF13417.1 CEH12735.1 - 3.4e-11 43.2 0.1 6.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEH12735.1 - 3.8e-08 33.2 0.0 6.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CEH12735.1 - 3.5e-05 23.7 0.0 5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CEH12735.1 - 0.00019 21.5 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CEH12735.1 - 0.00029 21.2 0.0 0.00057 20.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEH12735.1 - 0.0064 16.3 0.1 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain FBPase PF00316.15 CEH12736.1 - 4.1e-127 423.4 0.0 4.9e-127 423.2 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 CEH12736.1 - 0.00097 18.5 0.1 0.0017 17.6 0.0 1.4 2 0 0 2 2 2 1 Inositol monophosphatase family SPX PF03105.14 CEH12739.1 - 1.6e-45 156.0 0.0 2.2e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CEH12739.1 - 4e-26 91.9 35.8 5.3e-26 91.5 24.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CEH12739.1 - 2.5e-17 62.5 35.6 5.6e-12 44.8 13.5 2.2 1 1 1 2 2 2 2 Citrate transporter YbhQ PF11076.3 CEH12739.1 - 0.066 12.8 8.2 0.25 10.9 0.9 3.3 3 0 0 3 3 3 0 Putative inner membrane protein YbhQ COOH-NH2_lig PF14395.1 CEH12739.1 - 0.19 10.7 0.7 0.4 9.7 0.0 1.7 2 0 0 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 Rot1 PF10681.4 CEH12740.1 - 2.3e-62 210.1 2.4 2.9e-62 209.7 1.7 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal CKS PF01111.14 CEH12741.1 - 6e-35 118.8 1.4 8.2e-35 118.4 1.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF2036 PF09724.4 CEH12741.1 - 0.085 11.9 0.0 0.095 11.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) SNF2_N PF00176.18 CEH12742.1 - 1.7e-67 227.3 0.0 2.3e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEH12742.1 - 3.6e-13 49.1 0.0 9.6e-13 47.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEH12742.1 - 1.2e-08 34.6 0.0 3.2e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CEH12742.1 - 1.9e-06 26.9 0.1 3.9e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CEH12742.1 - 0.00052 19.9 0.0 0.0017 18.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CEH12742.1 - 0.21 10.5 0.0 0.39 9.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Prefoldin PF02996.12 CEH12743.1 - 0.0027 17.3 5.1 0.022 14.3 3.1 2.2 1 1 1 2 2 2 2 Prefoldin subunit DUF3373 PF11853.3 CEH12743.1 - 3.2 6.1 4.4 1.9 6.9 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) BHD_3 PF10405.4 CEH12744.1 - 4.1e-26 90.4 0.0 7.8e-26 89.5 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 CEH12744.1 - 3.1e-25 88.2 0.2 3.1e-25 88.2 0.2 2.1 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 CEH12744.1 - 1.5e-14 53.2 0.0 3.2e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CEH12744.1 - 1.2e-13 51.1 0.1 1.2e-13 51.1 0.0 3.4 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CEH12744.1 - 3.6e-06 27.1 0.6 2.2e-05 24.6 0.1 2.5 2 0 0 2 2 2 1 Transglutaminase-like superfamily COG7 PF10191.4 CEH12745.1 - 6.5e-41 140.1 6.7 2.1e-21 75.6 0.0 3.7 4 1 0 4 4 4 3 Golgi complex component 7 (COG7) DUF726 PF05277.7 CEH12746.1 - 9.9e-48 162.7 0.4 6.7e-47 160.0 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 CEH12746.1 - 0.0015 18.4 0.1 0.0089 15.9 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF3089 PF11288.3 CEH12746.1 - 0.05 12.7 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Brix PF04427.13 CEH12748.1 - 5.2e-17 62.1 0.0 2.1e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 Brix domain Zn_clus PF00172.13 CEH12749.1 - 1.5e-05 24.8 5.2 3.2e-05 23.7 3.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_21 PF13506.1 CEH12750.1 - 3.4e-19 68.7 0.1 6.4e-08 32.0 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 CEH12750.1 - 7.6e-16 58.6 0.2 2.2e-14 53.7 0.1 2.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Amidohydro_1 PF01979.15 CEH12753.1 - 1.6e-30 106.9 0.0 1.1e-13 51.5 0.0 3.2 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_5 PF13594.1 CEH12753.1 - 0.00024 20.8 0.0 0.001 18.8 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CEH12753.1 - 0.01 15.1 0.2 4.2 6.4 0.1 2.8 3 0 0 3 3 3 0 Amidohydrolase family TFIID-18kDa PF02269.11 CEH12754.1 - 1.1e-29 102.1 0.3 1.9e-28 98.1 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Adaptin_binding PF10199.4 CEH12754.1 - 0.013 15.7 1.0 0.013 15.7 0.7 2.1 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 MutS_II PF05188.12 CEH12754.1 - 0.13 12.3 1.6 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 MutS domain II Pkinase PF00069.20 CEH12755.1 - 4.7e-57 193.1 0.0 3.2e-56 190.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH12755.1 - 3.8e-22 78.5 0.0 1e-21 77.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH12755.1 - 1.7e-05 23.9 0.0 2.6e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CEH12755.1 - 0.031 14.0 0.0 0.17 11.6 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEH12755.1 - 0.045 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CoA_binding_2 PF13380.1 CEH12756.1 - 1.3e-27 96.3 0.0 1.5e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain GDI PF00996.13 CEH12757.1 - 1.3e-195 649.8 0.0 1.6e-195 649.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CEH12757.1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ribosomal_S15 PF00312.17 CEH12758.1 - 1.2e-16 60.2 0.7 2.9e-16 59.0 0.3 1.7 1 1 0 1 1 1 1 Ribosomal protein S15 SpoU_methylas_C PF12105.3 CEH12758.1 - 0.051 13.1 0.2 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal ETF_QO PF05187.8 CEH12759.1 - 7.2e-40 135.4 0.0 1.3e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CEH12759.1 - 7.8e-07 28.3 1.7 0.0011 17.9 1.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEH12759.1 - 3.3e-06 27.0 0.1 1.1e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CEH12759.1 - 1.5e-05 24.0 2.0 0.00016 20.6 1.2 2.1 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.9 CEH12759.1 - 0.00011 20.8 1.0 0.0002 19.9 0.7 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 CEH12759.1 - 0.00011 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEH12759.1 - 0.00047 19.1 0.1 0.00076 18.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CEH12759.1 - 0.00061 18.9 0.2 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 CEH12759.1 - 0.00096 18.9 0.3 0.0023 17.7 0.2 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 CEH12759.1 - 0.0011 18.1 0.1 0.0019 17.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CEH12759.1 - 0.003 17.6 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEH12759.1 - 0.0049 15.9 0.3 0.0088 15.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.2 CEH12759.1 - 0.02 15.2 1.0 0.054 13.8 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 CEH12759.1 - 0.042 13.6 0.6 0.085 12.6 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.1 CEH12759.1 - 0.075 12.8 0.7 0.16 11.8 0.5 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.17 CEH12759.1 - 0.13 11.0 0.5 0.2 10.4 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 CEH12759.1 - 0.14 10.7 2.1 0.1 11.2 0.4 1.5 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.1 CEH12759.1 - 0.26 10.1 0.0 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-RING_2 PF13639.1 CEH12760.1 - 2.4e-09 36.8 8.8 3.7e-09 36.2 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEH12760.1 - 1.5e-07 31.0 7.2 2.1e-07 30.4 5.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CEH12760.1 - 1.6e-06 28.0 1.8 2.9e-06 27.3 1.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CEH12760.1 - 4.5e-05 23.1 8.4 6.7e-05 22.5 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CEH12760.1 - 5.1e-05 23.2 9.5 7.9e-05 22.6 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH12760.1 - 0.0061 16.1 8.8 0.0096 15.5 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 CEH12761.1 - 1.5e-63 208.5 11.4 2.1e-11 43.2 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CEH12761.1 - 0.00086 17.5 3.7 1.3 7.0 0.0 4.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CEH12761.1 - 0.011 14.5 0.0 0.18 10.4 0.0 2.4 2 1 1 3 3 3 0 Nup133 N terminal like eIF2A PF08662.6 CEH12761.1 - 0.018 14.7 0.1 1.4 8.6 0.3 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 CEH12761.1 - 0.03 14.0 0.3 0.054 13.2 0.2 1.4 1 0 0 1 1 1 0 LisH Pirin PF02678.11 CEH12762.1 - 1e-27 96.0 0.4 2.1e-27 95.0 0.3 1.5 1 0 0 1 1 1 1 Pirin RibD_C PF01872.12 CEH12762.1 - 7.2e-27 94.3 0.1 2.8e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 RibD C-terminal domain Cupin_2 PF07883.6 CEH12762.1 - 3.4e-08 32.8 1.5 3.4e-06 26.4 0.2 3.1 3 0 0 3 3 3 2 Cupin domain His_Phos_1 PF00300.17 CEH12763.1 - 8.8e-27 94.1 0.0 2.5e-23 82.9 0.0 2.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) JmjC PF02373.17 CEH12764.1 - 8.2e-14 51.8 0.0 1.8e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CEH12764.1 - 0.0027 17.2 0.0 0.04 13.3 0.0 2.6 1 1 0 1 1 1 1 Cupin-like domain DUF2248 PF10005.4 CEH12764.1 - 0.049 12.5 3.1 0.083 11.7 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) zf-B_box PF00643.19 CEH12764.1 - 0.095 12.6 5.9 0.21 11.5 4.1 1.6 1 0 0 1 1 1 0 B-box zinc finger FYVE PF01363.16 CEH12764.1 - 0.79 9.6 12.0 0.028 14.3 3.8 1.9 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 CEH12764.1 - 8.4 6.3 13.5 2.4 8.0 4.0 3.0 2 1 0 2 2 2 0 Double zinc ribbon PRP1_N PF06424.7 CEH12766.1 - 6.8e-47 159.1 4.3 1.3e-46 158.2 2.2 2.1 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CEH12766.1 - 4.1e-23 79.7 39.2 0.037 14.6 0.0 13.2 6 5 7 13 13 13 9 Tetratricopeptide repeat TPR_16 PF13432.1 CEH12766.1 - 5.7e-15 55.5 31.8 0.021 15.5 0.0 8.7 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 CEH12766.1 - 4.8e-13 49.2 22.6 0.28 11.5 2.0 8.6 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 CEH12766.1 - 4.3e-09 35.5 2.4 0.0084 15.9 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 CEH12766.1 - 1.5e-06 27.7 15.6 0.23 11.1 0.0 7.5 8 0 0 8 8 8 2 TPR repeat TPR_6 PF13174.1 CEH12766.1 - 0.00034 20.8 14.6 9.3 6.9 0.0 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEH12766.1 - 0.0029 17.5 7.6 3.2 7.7 0.0 6.1 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 CEH12766.1 - 0.031 13.8 0.0 7.6 6.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat LSM PF01423.17 CEH12767.1 - 6e-20 70.5 0.0 6.8e-20 70.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CEH12767.1 - 0.0011 18.8 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain AA_permease PF00324.16 CEH12768.1 - 1.8e-83 280.5 36.2 2.3e-83 280.1 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEH12768.1 - 7.9e-22 77.3 34.7 1.1e-21 76.9 24.1 1.2 1 0 0 1 1 1 1 Amino acid permease Tocopherol_cycl PF14249.1 CEH12768.1 - 0.042 12.5 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 Tocopherol cyclase SKN1 PF03935.10 CEH12769.1 - 1.3e-83 280.8 0.0 1.6e-83 280.6 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 CEH12770.1 - 3.3e-84 282.8 0.0 4.4e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 CEH12770.1 - 0.00017 20.9 0.0 0.00033 19.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 VPEP PF07589.6 CEH12770.1 - 5.7 6.9 6.1 19 5.3 4.2 1.9 1 0 0 1 1 1 0 PEP-CTERM motif Cytochrom_B561 PF03188.11 CEH12771.1 - 1.1e-15 57.6 8.1 2.2e-15 56.6 5.6 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 CEH12771.1 - 0.028 14.1 2.0 0.028 14.1 1.4 2.9 4 0 0 4 4 4 0 PepSY-associated TM helix Cyclin PF08613.6 CEH12772.1 - 9.5e-10 39.0 0.0 8.3e-09 36.0 0.0 2.5 2 1 0 2 2 2 1 Cyclin KH_1 PF00013.24 CEH12774.1 - 1.6e-40 136.5 13.4 1.1e-16 60.2 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CEH12774.1 - 1.1e-27 95.1 15.7 2.3e-10 39.8 1.3 3.7 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 CEH12774.1 - 6.2e-11 41.6 5.5 0.0045 16.5 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CEH12774.1 - 9.3e-09 34.8 0.4 0.23 11.1 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CEH12774.1 - 0.0047 16.6 4.0 0.38 10.5 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain CLASP_N PF12348.3 CEH12775.1 - 1.6e-22 79.9 0.0 1.6e-07 30.9 0.0 4.5 4 0 0 4 4 4 4 CLASP N terminal HEAT_2 PF13646.1 CEH12775.1 - 8.4e-16 58.0 14.4 0.00062 19.9 0.0 8.5 7 2 1 8 8 8 4 HEAT repeats HEAT PF02985.17 CEH12775.1 - 9.6e-13 47.0 3.1 0.017 15.1 0.0 7.9 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 CEH12775.1 - 1.7e-07 31.5 7.3 0.21 12.1 0.1 7.0 5 1 1 6 6 6 2 HEAT-like repeat Adaptin_N PF01602.15 CEH12775.1 - 0.0045 15.3 0.1 6.7 4.9 0.0 3.8 4 0 0 4 4 4 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 CEH12775.1 - 0.03 12.5 0.0 2.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Pex2_Pex12 PF04757.9 CEH12776.1 - 3e-34 118.4 2.9 4.7e-34 117.7 2.0 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 CEH12776.1 - 0.13 12.1 2.4 1.2 9.0 0.3 2.4 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 CEH12776.1 - 3.4 7.7 10.7 0.088 12.8 1.4 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.23 CEH12777.1 - 5.3e-12 44.9 0.0 8.8e-12 44.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEH12777.1 - 6.1e-10 38.5 0.0 9.9e-10 37.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEH12777.1 - 2.5e-08 33.2 0.0 4.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain KTI12 PF08433.5 CEH12778.1 - 5e-52 176.7 0.0 1.1e-51 175.5 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 CEH12778.1 - 9.8e-09 35.2 1.6 2.9e-08 33.6 0.3 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEH12778.1 - 0.013 16.2 0.0 0.063 14.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain PCMT PF01135.14 CEH12779.1 - 1.3e-54 184.9 0.0 9.7e-40 136.3 0.0 2.2 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CEH12779.1 - 6.3e-08 32.6 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH12779.1 - 4.3e-07 30.4 0.0 6.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH12779.1 - 0.00025 20.6 0.1 0.00041 19.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CEH12779.1 - 0.0099 15.0 0.1 0.014 14.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 CEH12779.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 CEH12779.1 - 0.011 14.4 0.1 0.16 10.6 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 CEH12779.1 - 0.021 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 CEH12779.1 - 0.027 13.8 0.1 0.05 12.9 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.7 CEH12779.1 - 0.028 14.9 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HTH_DeoR PF08220.7 CEH12779.1 - 0.088 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MTS PF05175.9 CEH12779.1 - 0.096 12.0 0.1 0.39 10.0 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.1 CEH12779.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Prp18 PF02840.10 CEH12781.1 - 1.2e-56 190.5 0.1 3.2e-56 189.1 0.1 1.7 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 CEH12781.1 - 6.6e-09 34.8 3.4 1.8e-08 33.5 2.4 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like PMM PF03332.8 CEH12782.1 - 1.5e-99 331.9 0.1 2.2e-99 331.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase RabGAP-TBC PF00566.13 CEH12782.1 - 4.3e-22 78.6 0.0 1.5e-21 76.8 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Hydrolase_3 PF08282.7 CEH12782.1 - 0.14 11.7 0.0 0.5 9.8 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2346 PF09803.4 CEH12782.1 - 0.74 9.7 3.5 1.6 8.5 2.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) DUF4107 PF13389.1 CEH12783.1 - 0.14 11.8 0.1 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) GST_N_3 PF13417.1 CEH12785.1 - 5.8e-08 32.8 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEH12785.1 - 3.1e-07 30.2 0.0 1.2e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CEH12785.1 - 8.9e-05 22.4 0.2 0.0055 16.6 0.1 3.0 3 2 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEH12785.1 - 0.00016 21.4 2.0 0.0023 17.7 1.4 2.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Dor1 PF04124.7 CEH12786.1 - 4.6e-13 48.3 7.1 9.2e-13 47.3 2.9 2.4 2 0 0 2 2 2 2 Dor1-like family Rcd1 PF04078.8 CEH12787.1 - 1.5e-127 423.8 0.9 1.9e-127 423.5 0.6 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Scs3p PF10261.4 CEH12788.1 - 1.2e-39 135.7 1.8 9.4e-26 90.3 0.0 2.6 2 1 0 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM CytB6-F_Fe-S PF08802.5 CEH12788.1 - 6.7 6.8 6.2 26 4.9 0.0 3.6 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Hexokinase_2 PF03727.11 CEH12789.1 - 5e-79 264.9 0.0 6.5e-79 264.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CEH12789.1 - 5.4e-67 225.1 0.0 9.8e-67 224.2 0.0 1.4 1 0 0 1 1 1 1 Hexokinase DUF2834 PF11196.3 CEH12790.1 - 0.022 14.8 13.3 0.23 11.6 0.6 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2834) DUF2189 PF09955.4 CEH12790.1 - 0.8 9.6 8.0 0.72 9.7 0.4 2.8 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2189) DUF3357 PF11837.3 CEH12790.1 - 9.8 6.0 10.3 63 3.4 3.9 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF3357) Peptidase_M20 PF01546.23 CEH12794.1 - 4.6e-20 71.9 0.0 7.7e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CEH12794.1 - 1.3e-09 37.7 0.0 3.3e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CEH12794.1 - 0.0048 16.6 0.0 0.024 14.3 0.0 2.1 2 1 0 2 2 2 1 Peptidase family M28 CRAL_TRIO PF00650.15 CEH12795.1 - 2.3e-39 134.4 0.0 3.1e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CEH12795.1 - 1.5e-09 37.9 0.0 2.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEH12795.1 - 0.00099 19.1 0.1 0.0023 18.0 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TRM PF02005.11 CEH12796.1 - 7.4e-110 367.3 0.0 9.2e-82 274.9 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase 2C_adapt PF08793.5 CEH12796.1 - 0.05 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain Glycophorin_A PF01102.13 CEH12797.1 - 0.17 11.6 2.7 0.17 11.6 0.9 1.8 2 0 0 2 2 2 0 Glycophorin A GTP_EFTU PF00009.22 CEH12798.1 - 6.1e-55 185.5 0.0 1.1e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CEH12798.1 - 1.3e-31 108.6 0.5 3e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 CEH12798.1 - 5.1e-30 103.1 0.1 1.7e-29 101.4 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 CEH12798.1 - 3.8e-25 87.5 0.0 8.5e-25 86.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CEH12798.1 - 8.5e-13 48.2 0.0 3.1e-12 46.4 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Glyco_hydro_28 PF00295.12 CEH12800.1 - 3.9e-40 137.7 0.0 5.2e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 CEH12800.1 - 0.011 15.8 0.0 0.085 12.9 0.0 2.2 1 1 0 1 1 1 0 Pectate lyase superfamily protein Beta_helix PF13229.1 CEH12800.1 - 0.043 13.5 0.2 0.15 11.8 0.1 1.8 1 1 1 2 2 2 0 Right handed beta helix region GMC_oxred_N PF00732.14 CEH12802.1 - 0.031 13.4 0.2 0.037 13.1 0.1 1.1 1 0 0 1 1 1 0 GMC oxidoreductase RILP PF11461.3 CEH12802.1 - 0.063 13.4 0.9 0.14 12.3 0.6 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein DUF3858 PF12970.2 CEH12804.1 - 0.057 13.1 0.1 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3858) PspB PF06667.7 CEH12804.1 - 0.16 11.8 1.3 0.19 11.6 0.2 1.6 2 0 0 2 2 2 0 Phage shock protein B rve PF00665.21 CEH12806.1 - 4.9e-15 55.7 0.0 2e-14 53.7 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEH12806.1 - 2.8e-13 49.7 0.0 9.1e-13 48.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ADH_zinc_N PF00107.21 CEH12807.1 - 2e-07 30.5 0.0 3.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TP_methylase PF00590.15 CEH12808.1 - 3.1e-35 121.7 0.3 1.9e-34 119.2 0.2 2.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 CEH12808.1 - 6.2e-09 36.0 0.0 1.5e-07 31.6 0.0 2.9 3 1 0 3 3 3 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CEH12808.1 - 7.2e-07 28.4 4.3 2.8e-05 23.3 0.5 2.5 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CEH12808.1 - 3.4e-05 22.7 0.1 6.3e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central PH PF00169.24 CEH12809.1 - 1.5e-07 31.5 0.2 3.2e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 PH domain RICTOR_M PF14666.1 CEH12809.1 - 0.065 12.2 0.3 0.1 11.5 0.2 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Vps23_core PF09454.5 CEH12809.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Vps23 core domain DUF2890 PF11081.3 CEH12809.1 - 1.8 8.6 9.6 3.6 7.5 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Mito_carr PF00153.22 CEH12811.1 - 2.8e-65 216.0 0.2 7.7e-25 86.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein M-factor PF03855.8 CEH12811.1 - 0.27 11.2 1.0 1.3 9.1 0.1 2.5 3 0 0 3 3 3 0 M-factor Glug PF07581.7 CEH12811.1 - 0.43 10.8 2.8 0.44 10.8 0.1 2.4 3 0 0 3 3 3 0 The GLUG motif DUF3292 PF11696.3 CEH12812.1 - 4.5e-09 34.7 0.1 0.00017 19.6 0.0 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF3292) Pex24p PF06398.6 CEH12812.1 - 0.3 9.8 0.0 0.49 9.1 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin LIP PF03583.9 CEH12814.1 - 4.4e-58 196.7 0.1 6.1e-58 196.3 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 CEH12814.1 - 3.7e-07 30.0 0.8 2.1e-06 27.5 0.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH12814.1 - 1.7e-05 24.8 0.0 3.9e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEH12814.1 - 0.35 10.0 5.9 8 5.6 1.1 2.8 1 1 1 2 2 2 0 Prolyl oligopeptidase family HLH PF00010.21 CEH12816.1 - 3.2e-07 29.9 4.7 6.4e-07 28.9 3.2 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Selenoprotein_S PF06936.6 CEH12816.1 - 0.31 10.5 7.3 0.42 10.1 4.9 1.3 1 1 0 1 1 1 0 Selenoprotein S (SelS) SRRM_C PF15230.1 CEH12816.1 - 2 8.5 10.2 0.2 11.7 3.8 1.8 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Remorin_C PF03763.8 CEH12816.1 - 2.4 7.7 8.7 2.4 7.7 5.6 1.3 1 1 0 1 1 1 0 Remorin, C-terminal region DUF2423 PF10338.4 CEH12816.1 - 10 6.2 12.0 0.21 11.6 2.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2423) zf-C2H2 PF00096.21 CEH12819.1 - 5.9e-07 29.4 12.3 0.00046 20.3 1.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEH12819.1 - 1.1e-05 25.4 3.8 1.1e-05 25.4 2.7 2.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEH12819.1 - 3.4e-05 23.8 11.1 0.012 15.9 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEH12819.1 - 0.2 11.5 1.7 0.47 10.4 0.5 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger SKN1 PF03935.10 CEH12820.1 - 2.2e-189 629.7 0.6 2.6e-189 629.5 0.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) CAP_N PF01213.14 CEH12824.1 - 0.72 9.0 6.8 14 4.7 5.3 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal P16-Arc PF04699.9 CEH12826.1 - 1.2e-46 158.5 0.0 1.3e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Phage-MuB_C PF09077.6 CEH12826.1 - 0.032 13.9 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Mu B transposition protein, C terminal Utp12 PF04003.7 CEH12826.1 - 0.048 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family TPR_11 PF13414.1 CEH12828.1 - 6.1e-14 51.4 4.9 7e-10 38.4 0.9 6.4 7 1 1 8 8 8 2 TPR repeat TPR_1 PF00515.23 CEH12828.1 - 4.9e-12 44.9 1.3 0.00036 20.0 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat Ins_P5_2-kin PF06090.7 CEH12828.1 - 9.5e-12 44.5 0.0 2.8e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Inositol-pentakisphosphate 2-kinase TPR_2 PF07719.12 CEH12828.1 - 3e-11 42.3 17.9 2e-05 24.1 0.1 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEH12828.1 - 1e-09 38.2 19.9 9.5e-05 22.2 0.5 7.1 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEH12828.1 - 1.2e-09 38.5 3.1 1.2e-09 38.5 2.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEH12828.1 - 1.9e-09 37.7 8.4 0.00069 19.9 0.5 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEH12828.1 - 1.5e-08 33.7 0.2 0.3 10.9 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEH12828.1 - 2.1e-07 30.6 6.4 0.00013 21.8 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH12828.1 - 8.1e-07 29.1 3.5 0.00052 20.4 0.8 9.8 6 4 5 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEH12828.1 - 8.1e-05 22.1 14.5 0.073 12.8 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 CEH12828.1 - 0.011 15.8 3.5 1.2 9.2 0.2 4.1 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CEH12828.1 - 0.82 9.5 22.5 0.13 12.0 1.5 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 CEH12828.1 - 4.3 7.4 23.5 0.99 9.4 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.20 CEH12830.1 - 2e-66 223.8 0.0 6.9e-66 222.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH12830.1 - 2.3e-36 125.2 0.0 4.3e-32 111.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEH12830.1 - 9e-07 28.1 0.0 2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.14 CEH12830.1 - 9.5e-05 21.7 0.1 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.17 CEH12830.1 - 0.017 14.4 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Rep_fac-A_3 PF08661.6 CEH12831.1 - 2.2e-25 88.6 0.0 2.5e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Myosin_N PF02736.14 CEH12831.1 - 0.057 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain tRNA_anti-codon PF01336.20 CEH12831.1 - 0.061 13.1 0.3 0.088 12.6 0.2 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Hat1_N PF10394.4 CEH12832.1 - 6.7e-38 130.2 0.0 9.6e-21 74.5 0.0 2.4 1 1 1 2 2 2 2 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 CEH12832.1 - 0.00011 22.3 0.0 0.00042 20.4 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 CEH12832.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_1 PF00583.19 CEH12832.1 - 0.015 15.3 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AP-5_subunit_s1 PF15001.1 CEH12832.1 - 0.021 14.7 1.1 4.5 7.1 0.0 2.7 3 0 0 3 3 3 0 AP-5 complex subunit sigma-1 RanGAP1_C PF07834.6 CEH12832.1 - 0.024 14.0 0.0 5.2 6.4 0.0 2.2 2 0 0 2 2 2 0 RanGAP1 C-terminal domain Acyl-CoA_dh_M PF02770.14 CEH12833.1 - 2.5e-07 30.0 0.6 1.1e-06 28.0 0.2 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CEH12833.1 - 4.1e-07 30.2 0.0 9.3e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.14 CEH12833.1 - 0.057 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA oxidase LRR19-TM PF15176.1 CEH12836.1 - 3.1 7.5 6.6 2.2 8.0 0.2 2.8 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Mitofilin PF09731.4 CEH12837.1 - 5.8e-63 213.4 21.3 1.3e-33 116.5 10.7 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Apolipoprotein PF01442.13 CEH12837.1 - 0.00011 21.8 16.9 0.00069 19.1 2.2 2.5 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain EmrE PF13536.1 CEH12837.1 - 0.22 11.7 0.0 0.38 10.9 0.0 1.3 1 0 0 1 1 1 0 Multidrug resistance efflux transporter SAP PF02037.22 CEH12838.1 - 3.7e-12 45.4 1.5 5.1e-12 44.9 0.3 1.9 2 0 0 2 2 2 1 SAP domain Aminotran_5 PF00266.14 CEH12839.1 - 4.6e-06 25.6 0.0 8.1e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V XPA_C PF05181.7 CEH12840.1 - 2.4e-27 94.2 3.4 4.3e-27 93.4 2.4 1.4 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 CEH12840.1 - 0.00012 21.6 0.3 0.00022 20.8 0.2 1.4 1 0 0 1 1 1 1 XPA protein N-terminal WLM PF08325.5 CEH12841.1 - 3.8e-44 150.7 0.1 6.8e-44 149.9 0.1 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 CEH12841.1 - 7.2e-06 24.9 13.4 9.7e-06 24.5 2.3 3.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Rotamase PF00639.16 CEH12841.1 - 0.11 13.2 1.5 1.6 9.5 0.0 3.3 3 1 2 5 5 5 0 PPIC-type PPIASE domain DZR PF12773.2 CEH12841.1 - 0.19 11.5 8.6 0.45 10.3 5.9 1.7 1 0 0 1 1 1 0 Double zinc ribbon Rotamase_2 PF13145.1 CEH12841.1 - 8.1 7.1 0.0 8.1 7.1 0.0 2.9 3 1 0 3 3 3 0 PPIC-type PPIASE domain SUV3_C PF12513.3 CEH12842.1 - 2e-12 46.3 0.3 5.6e-12 44.9 0.2 1.9 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CEH12842.1 - 1.6e-08 34.3 0.0 3.4e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CPDase PF07823.6 CEH12843.1 - 3.9e-23 81.9 0.0 4.9e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 CEH12843.1 - 9e-05 22.2 0.5 0.021 14.5 0.1 2.2 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 CEH12843.1 - 0.017 15.0 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 LigT like Phosphoesterase SNF2_N PF00176.18 CEH12844.1 - 2.2e-61 207.2 0.0 5.5e-61 205.9 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad54_N PF08658.5 CEH12844.1 - 4.2e-40 137.6 0.0 1.1e-39 136.2 0.0 1.7 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 CEH12844.1 - 2.3e-11 43.3 0.0 7.1e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CEH12844.1 - 4.7e-07 28.9 0.0 2e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CEH12844.1 - 0.024 14.4 0.0 0.17 11.6 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CEH12844.1 - 0.031 14.4 0.0 0.4 10.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain BSP PF04450.7 CEH12846.1 - 2.2e-41 141.6 0.0 2.7e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 CEH12846.1 - 1e-06 28.8 0.1 1.5e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 CEH12846.1 - 7e-06 25.7 1.6 8.8e-06 25.4 0.5 1.5 1 1 0 1 1 1 1 SprT-like family Peptidase_M76 PF09768.4 CEH12846.1 - 0.046 13.1 0.3 0.078 12.4 0.0 1.4 2 0 0 2 2 2 0 Peptidase M76 family DUF3437 PF11919.3 CEH12847.1 - 3.8e-26 90.6 0.1 3.6e-25 87.4 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 CEH12847.1 - 1.7e-07 30.7 0.5 0.0022 17.8 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 CEH12847.1 - 2.6e-05 24.4 10.4 0.00071 19.8 0.1 5.3 4 0 0 4 4 4 1 HEAT repeats Arm PF00514.18 CEH12847.1 - 0.00015 21.4 0.0 0.0017 18.0 0.0 3.0 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CEH12847.1 - 0.006 17.0 3.9 0.067 13.7 0.0 4.9 5 0 0 5 5 5 1 HEAT-like repeat VWA_2 PF13519.1 CEH12848.1 - 1.3e-15 57.9 0.1 2.1e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CEH12848.1 - 1.6e-07 31.1 0.1 2.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 CEH12848.1 - 9.3e-07 27.8 2.5 0.0008 18.7 1.6 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif Ssl1 PF04056.9 CEH12848.1 - 1.8e-06 27.7 0.0 2.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like ETF PF01012.16 CEH12848.1 - 0.01 15.5 0.2 0.024 14.3 0.0 1.6 2 0 0 2 2 2 0 Electron transfer flavoprotein domain PDH PF02153.12 CEH12848.1 - 0.044 12.6 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase CGI-121 PF08617.5 CEH12848.1 - 0.046 13.3 0.2 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 Kinase binding protein CGI-121 YjeF_N PF03853.10 CEH12848.1 - 0.051 13.1 0.1 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 YjeF-related protein N-terminus DUF521 PF04412.8 CEH12848.1 - 0.064 11.8 0.0 1 7.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF521) Neugrin PF06413.6 CEH12848.1 - 0.092 12.5 1.4 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Neugrin Dynein_heavy PF03028.10 CEH12848.1 - 0.16 9.9 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor STE3 PF02076.10 CEH12850.1 - 2.8e-78 262.8 9.2 3.4e-78 262.5 6.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor MARVEL PF01284.18 CEH12850.1 - 0.9 9.3 12.2 0.027 14.2 3.0 2.6 2 1 1 3 3 3 0 Membrane-associating domain Pheromone PF08015.6 CEH12851.1 - 0.037 14.8 0.0 3.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Fungal mating-type pheromone STE3 PF02076.10 CEH12852.1 - 3.5e-68 229.7 4.1 4.1e-68 229.5 2.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.7 CEH12852.1 - 0.059 12.7 0.3 0.24 10.8 0.1 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor HemY_N PF07219.8 CEH12852.1 - 0.28 10.7 1.9 0.58 9.7 1.3 1.6 1 0 0 1 1 1 0 HemY protein N-terminus DUF912 PF06024.7 CEH12852.1 - 0.36 10.8 1.0 2.2 8.3 0.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) IKKbetaNEMObind PF12179.3 CEH12853.1 - 0.0079 15.9 0.7 0.021 14.6 0.1 1.9 2 0 0 2 2 2 1 I-kappa-kinase-beta NEMO binding domain Lactamase_B_2 PF12706.2 CEH12853.1 - 0.033 13.7 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain RNase_H2-Ydr279 PF09468.5 CEH12854.1 - 3.8e-28 98.5 0.0 9.8e-24 84.0 0.0 2.1 2 0 0 2 2 2 2 Ydr279p protein family (RNase H2 complex component) Cation_ATPase_N PF00690.21 CEH12854.1 - 0.18 11.2 0.7 1.3 8.5 0.2 2.3 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus NmrA PF05368.8 CEH12855.1 - 8.2e-19 67.7 0.0 1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Ribosomal_S19 PF00203.16 CEH12858.1 - 1.6e-24 85.3 0.0 1.7e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_S13_N PF08069.7 CEH12860.1 - 4e-25 87.4 0.1 8.7e-25 86.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CEH12860.1 - 1.7e-21 75.7 0.0 2.7e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 CEH12860.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain Ribosomal_S6e PF01092.14 CEH12861.1 - 6.7e-52 174.4 0.3 1.3e-51 173.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Exo_endo_phos PF03372.18 CEH12862.1 - 1.3e-21 77.7 0.2 1.7e-21 77.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fork_head PF00250.13 CEH12863.1 - 1.6e-10 40.8 0.1 3.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Fork head domain BNIP3 PF06553.7 CEH12863.1 - 0.25 10.6 4.7 0.53 9.6 3.3 1.5 1 0 0 1 1 1 0 BNIP3 PAT1 PF09770.4 CEH12863.1 - 6.6 4.8 9.0 8.8 4.4 6.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lipase_3 PF01764.20 CEH12865.1 - 1.3e-16 60.4 0.0 2.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CEH12865.1 - 0.018 14.8 0.0 0.062 13.0 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family DHHW PF14286.1 CEH12865.1 - 1.6 7.9 1.7 2.5 7.3 1.2 1.2 1 0 0 1 1 1 0 DHHW protein RRM_1 PF00076.17 CEH12866.1 - 9.8e-16 57.1 0.0 1.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH12866.1 - 7.3e-13 48.3 0.0 1.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH12866.1 - 7.5e-07 28.8 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nuc_sug_transp PF04142.10 CEH12867.1 - 2.6e-06 26.7 0.1 4.9e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 CEH12867.1 - 0.0039 17.2 7.2 0.0039 17.2 5.0 3.7 3 1 1 4 4 4 1 EamA-like transporter family TPT PF03151.11 CEH12867.1 - 0.019 14.6 0.8 0.019 14.6 0.5 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family UAA PF08449.6 CEH12867.1 - 0.35 9.7 12.0 0.2 10.5 2.3 2.1 2 0 0 2 2 2 0 UAA transporter family Chorismate_bind PF00425.13 CEH12868.1 - 1.7e-76 256.9 0.0 2.5e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 CEH12868.1 - 4.2e-28 98.1 0.0 3.3e-27 95.1 0.0 2.2 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region zinc_ribbon_4 PF13717.1 CEH12869.1 - 0.075 12.7 0.2 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CEH12869.1 - 0.097 12.2 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Shisa PF13908.1 CEH12871.1 - 0.013 15.6 0.0 0.013 15.6 0.0 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Tetraspannin PF00335.15 CEH12871.1 - 0.021 14.1 8.8 0.076 12.2 4.1 2.1 2 0 0 2 2 2 0 Tetraspanin family WBP-1 PF11669.3 CEH12871.1 - 0.063 13.3 1.6 1 9.4 0.0 2.5 3 0 0 3 3 3 0 WW domain-binding protein 1 Protocadherin PF08374.6 CEH12871.1 - 0.15 11.7 0.1 0.32 10.6 0.0 1.5 2 0 0 2 2 2 0 Protocadherin PRA1 PF03208.14 CEH12871.1 - 1.6 8.0 6.1 3 7.1 2.4 2.4 2 1 0 2 2 2 0 PRA1 family protein Pyr_redox_3 PF13738.1 CEH12873.1 - 1.4e-12 48.0 0.0 1.1e-05 25.6 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CEH12873.1 - 1.2e-11 43.5 0.0 9.2e-06 24.1 0.0 2.3 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 CEH12873.1 - 8.3e-08 32.1 0.0 2.3e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CEH12873.1 - 0.0005 19.1 0.0 0.0084 15.0 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CEH12873.1 - 0.00076 19.4 0.0 4.2 7.2 0.0 3.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEH12873.1 - 0.084 11.7 0.0 5.5 5.7 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 CEH12873.1 - 0.11 11.3 0.0 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GST_C_2 PF13410.1 CEH12874.1 - 1.2e-09 37.9 0.0 2.8e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEH12874.1 - 4.7e-09 36.1 0.0 1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CEH12874.1 - 2.5e-08 34.0 0.0 5.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEH12874.1 - 1.1e-07 31.9 0.0 2.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEH12874.1 - 7.2e-07 29.1 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RRM_1 PF00076.17 CEH12876.1 - 1.9e-23 81.8 0.0 2.3e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH12876.1 - 1.6e-15 56.8 0.0 5.4e-08 32.6 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH12876.1 - 2.2e-15 56.2 0.0 2.3e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 CEH12876.1 - 2.6e-09 36.0 0.0 0.0059 16.0 0.0 3.6 3 0 0 3 3 3 3 Pumilio-family RNA binding repeat Acyltransferase PF01553.16 CEH12879.1 - 6.5e-22 77.3 0.0 1.3e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Mid1 PF12929.2 CEH12882.1 - 3.5e-61 207.2 0.1 4.8e-61 206.7 0.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component fn3 PF00041.16 CEH12882.1 - 0.028 14.5 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Fibronectin type III domain Fz PF01392.17 CEH12882.1 - 0.2 12.0 1.1 0.48 10.7 0.0 2.1 2 1 0 2 2 2 0 Fz domain DDOST_48kD PF03345.9 CEH12884.1 - 5.5e-65 219.5 0.0 7.7e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta zf-DHHC PF01529.15 CEH12884.1 - 1.7e-07 30.7 0.1 3.9e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase TctB PF07331.6 CEH12884.1 - 0.0056 16.3 2.4 0.016 14.8 0.1 2.4 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family zf-Nse PF11789.3 CEH12885.1 - 2e-18 65.6 0.1 3.4e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CEH12885.1 - 3.4e-08 33.3 0.0 7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 CEH12885.1 - 0.0045 16.6 0.3 0.0086 15.7 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 CEH12885.1 - 0.013 15.2 1.1 0.022 14.5 0.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.15 CEH12885.1 - 0.026 14.0 1.3 0.051 13.0 0.9 1.5 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 CEH12885.1 - 0.065 13.0 0.1 0.18 11.6 0.2 1.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CEH12885.1 - 0.083 12.5 0.2 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3126 PF11324.3 CEH12885.1 - 0.096 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) Prefoldin PF02996.12 CEH12886.1 - 9.9e-27 92.9 0.4 1.4e-26 92.5 0.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Sec1 PF00995.18 CEH12886.1 - 0.0039 15.8 1.1 0.0052 15.4 0.7 1.1 1 0 0 1 1 1 1 Sec1 family DUF3352 PF11832.3 CEH12886.1 - 0.018 13.3 0.0 0.029 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) CNTF PF01110.12 CEH12886.1 - 0.077 12.2 0.7 0.14 11.4 0.5 1.4 1 0 0 1 1 1 0 Ciliary neurotrophic factor Ribosomal_L28e PF01778.12 CEH12887.1 - 1.1e-20 74.2 0.2 1.6e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Pkinase PF00069.20 CEH12888.1 - 1.6e-42 145.4 0.0 8.3e-41 139.8 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH12888.1 - 5.6e-21 74.7 0.0 1.4e-20 73.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.1 CEH12891.1 - 0.068 13.1 0.0 0.21 11.5 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat Vps26 PF03643.10 CEH12892.1 - 1.6e-129 430.5 1.8 1.8e-129 430.3 1.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CEH12892.1 - 0.0051 16.6 0.9 0.53 10.1 0.0 3.2 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Glyco_transf_8C PF08437.5 CEH12893.1 - 0.12 12.3 0.1 3.2 7.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal Ras PF00071.17 CEH12894.1 - 1.3e-52 177.4 0.0 1.5e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH12894.1 - 5.8e-17 62.2 0.0 8.1e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH12894.1 - 6.8e-06 25.4 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEH12894.1 - 0.023 14.1 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CEH12894.1 - 0.053 13.0 0.0 5 6.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CAF1A PF12253.3 CEH12896.1 - 1e-21 76.8 4.2 1e-21 76.8 2.9 2.8 3 0 0 3 3 3 1 Chromatin assembly factor 1 subunit A AA_kinase PF00696.23 CEH12897.1 - 2.1e-39 135.5 0.3 3.6e-39 134.7 0.2 1.4 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CEH12897.1 - 1.1e-10 41.0 0.8 3.7e-05 23.3 0.0 3.3 3 0 0 3 3 3 2 PUA domain GATase_5 PF13507.1 CEH12898.1 - 1e-92 309.7 0.0 1.5e-92 309.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CEH12898.1 - 1.3e-43 148.6 2.0 4.6e-23 81.9 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CEH12898.1 - 4.2e-22 78.1 1.0 1.3e-21 76.6 0.0 2.5 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain DUF1490 PF07371.7 CEH12898.1 - 0.035 14.0 4.4 0.18 11.7 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1490) Peroxidase_2 PF01328.12 CEH12899.1 - 0.032 12.8 0.1 2.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Peroxidase, family 2 DUF3072 PF11272.3 CEH12902.1 - 0.051 13.2 0.1 0.69 9.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) Dimer_Tnp_hAT PF05699.9 CEH12902.1 - 0.094 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF3072 PF11272.3 CEH12904.1 - 0.051 13.2 0.1 0.69 9.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) Dimer_Tnp_hAT PF05699.9 CEH12904.1 - 0.094 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RINGv PF12906.2 CEH12906.1 - 0.012 15.5 0.3 0.021 14.8 0.2 1.4 1 0 0 1 1 1 0 RING-variant domain DUF308 PF03729.8 CEH12906.1 - 0.24 11.4 9.0 0.54 10.2 0.4 3.2 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Rhomboid PF01694.17 CEH12907.1 - 4.5e-08 33.2 15.8 0.00054 20.0 5.7 2.5 2 0 0 2 2 2 2 Rhomboid family Ribonuclease PF00545.15 CEH12908.1 - 1.4e-11 44.3 0.8 1.9e-11 43.8 0.5 1.2 1 0 0 1 1 1 1 ribonuclease Ras PF00071.17 CEH12909.1 - 3.2e-53 179.4 0.0 3.7e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH12909.1 - 9.1e-16 58.4 0.0 1.3e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH12909.1 - 6e-07 28.8 0.0 8.1e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Brr6_like_C_C PF10104.4 CEH12910.1 - 2.2e-27 95.2 0.0 3.1e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF2890 PF11081.3 CEH12910.1 - 0.5 10.4 6.7 0.037 14.0 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) MFS_1 PF07690.11 CEH12912.1 - 8.2e-23 80.6 34.3 1.4e-22 79.9 23.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CEH12912.1 - 0.017 13.3 3.0 0.026 12.7 2.1 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) WSC PF01822.14 CEH12913.1 - 1.3e-44 149.9 39.1 1e-15 57.3 2.8 3.3 3 0 0 3 3 3 3 WSC domain RNA_pol_N PF01194.12 CEH12914.1 - 4.6e-30 103.4 0.5 5.3e-30 103.2 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit ApoO PF09769.4 CEH12915.1 - 2.4e-30 105.3 0.1 5.1e-30 104.2 0.0 1.5 2 0 0 2 2 2 1 Apolipoprotein O Methyltransf_10 PF05971.7 CEH12916.1 - 7.2e-56 189.5 0.0 2.6e-38 131.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF890) Methyltransf_18 PF12847.2 CEH12916.1 - 0.065 13.8 0.1 0.26 11.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain HEAT PF02985.17 CEH12917.1 - 8.7e-20 68.9 7.8 0.00021 21.1 0.0 10.4 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 CEH12917.1 - 7.8e-16 58.0 17.0 1.6e-06 28.4 0.0 8.8 7 1 2 9 9 9 5 HEAT-like repeat HEAT_2 PF13646.1 CEH12917.1 - 1.9e-13 50.5 2.6 6.1e-06 26.4 0.0 8.5 3 2 4 7 7 7 4 HEAT repeats IBN_N PF03810.14 CEH12917.1 - 7.2e-09 35.4 0.1 6.3e-07 29.2 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 CEH12917.1 - 2.7e-06 26.9 11.3 0.00058 19.5 0.0 5.6 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 CEH12917.1 - 0.0067 14.8 0.1 0.18 10.1 0.0 2.5 2 0 0 2 2 2 1 Adaptin N terminal region CLASP_N PF12348.3 CEH12917.1 - 0.024 13.9 0.0 2.3 7.5 0.0 3.7 3 0 0 3 3 3 0 CLASP N terminal DUF3385 PF11865.3 CEH12917.1 - 0.14 12.0 0.5 3.4 7.5 0.0 3.4 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) PgaD PF13994.1 CEH12918.1 - 0.13 11.7 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 PgaD-like protein BPL_LplA_LipB PF03099.14 CEH12919.1 - 1.3e-13 50.9 0.0 6.7e-13 48.7 0.0 2.0 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family RINGv PF12906.2 CEH12920.1 - 4.4e-06 26.6 9.8 7.5e-06 25.8 6.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CEH12920.1 - 0.011 15.5 5.4 0.021 14.6 3.8 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 CEH12920.1 - 0.019 14.5 3.5 0.038 13.5 2.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CEH12920.1 - 0.031 14.3 4.0 0.058 13.4 2.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CEH12920.1 - 0.087 12.5 4.0 0.15 11.7 2.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CEH12920.1 - 0.32 10.9 4.0 0.61 10.0 2.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain RNA_polI_A34 PF08208.6 CEH12921.1 - 1.1e-07 31.7 4.7 0.021 14.4 0.0 3.1 2 1 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 RRM_1 PF00076.17 CEH12922.1 - 1.2e-11 44.0 0.0 1.7e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH12922.1 - 3.5e-09 36.5 0.0 4.8e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH12922.1 - 3.2e-06 26.9 0.0 4.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NIF3 PF01784.13 CEH12924.1 - 1.7e-51 175.1 0.0 2.2e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) HLH PF00010.21 CEH12925.1 - 3.5e-08 33.0 0.6 6.3e-08 32.1 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TPR_MLP1_2 PF07926.7 CEH12925.1 - 0.028 14.1 9.3 0.18 11.5 1.2 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein MRP-S31 PF15433.1 CEH12925.1 - 0.028 13.8 2.7 0.053 12.9 1.8 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 eIF-5a PF01287.15 CEH12926.1 - 2.5e-24 84.9 0.1 3.6e-24 84.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CEH12926.1 - 0.00011 21.8 0.5 0.00025 20.6 0.4 1.7 1 0 0 1 1 1 1 KOW motif TgMIC1 PF11476.3 CEH12926.1 - 0.0018 17.7 0.0 0.0037 16.7 0.0 1.5 1 0 0 1 1 1 1 Toxoplasma gondii micronemal protein 1 TgMIC1 EFP_N PF08207.7 CEH12926.1 - 0.02 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Adap_comp_sub PF00928.16 CEH12927.1 - 1.4e-20 73.5 0.0 2.2e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CEH12927.1 - 1.2e-07 31.5 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LSM PF01423.17 CEH12928.1 - 9.4e-17 60.3 0.0 1.2e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain FA_desaturase PF00487.19 CEH12929.1 - 6.2e-32 111.0 20.6 1.2e-31 110.0 14.3 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CEH12929.1 - 4.5e-09 35.9 0.0 1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TctB PF07331.6 CEH12931.1 - 0.35 10.5 9.8 2.1 7.9 4.6 2.4 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family RCR PF12273.3 CEH12931.1 - 0.36 11.3 5.9 1.8 9.1 4.1 2.2 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red FA_desaturase PF00487.19 CEH12931.1 - 3.3 7.0 8.1 0.52 9.7 0.8 2.1 1 1 1 2 2 2 0 Fatty acid desaturase PI3_PI4_kinase PF00454.22 CEH12932.1 - 5.3e-24 84.9 0.0 7.8e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4279 PF14106.1 CEH12933.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) DUF3649 PF12365.3 CEH12933.1 - 0.95 9.0 3.9 2.9 7.4 2.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) SurE PF01975.12 CEH12934.1 - 2.8e-11 43.1 0.0 4.2e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE DUF3180 PF11377.3 CEH12934.1 - 0.069 13.0 1.5 0.14 12.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Imm_superinfect PF14373.1 CEH12934.1 - 0.12 12.0 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Superinfection immunity protein RED_N PF07808.8 CEH12935.1 - 3.4e-05 23.2 2.7 3.4e-05 23.2 1.9 1.9 2 0 0 2 2 2 1 RED-like protein N-terminal region Mus7 PF09462.5 CEH12936.1 - 4.3e-116 389.2 2.4 6.5e-116 388.6 1.7 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Ribonucleas_3_2 PF11469.3 CEH12936.1 - 0.077 13.1 0.1 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III Peptidase_M61 PF05299.7 CEH12936.1 - 0.1 12.5 0.0 5.1 7.1 0.0 2.6 2 0 0 2 2 2 0 M61 glycyl aminopeptidase F-box-like PF12937.2 CEH12938.1 - 2.6e-05 23.8 0.1 8.1e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH12938.1 - 0.09 12.4 0.2 0.42 10.3 0.0 2.3 2 0 0 2 2 2 0 F-box domain DHBP_synthase PF00926.14 CEH12939.1 - 2.1e-63 213.0 0.1 2.3e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PEP-utilizers PF00391.18 CEH12939.1 - 0.052 13.1 0.3 0.23 11.0 0.0 2.2 2 1 1 3 3 3 0 PEP-utilising enzyme, mobile domain SNARE_assoc PF09335.6 CEH12940.1 - 0.0015 18.7 1.9 0.0015 18.7 1.3 1.9 1 1 0 1 1 1 1 SNARE associated Golgi protein CbiM PF01891.11 CEH12940.1 - 0.37 10.3 6.8 0.55 9.7 4.7 1.1 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Glyco_hydro_20 PF00728.17 CEH12941.1 - 1.4e-73 248.0 0.0 1.9e-73 247.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CEH12941.1 - 4.5e-07 30.5 0.9 3.6e-06 27.6 0.6 2.4 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CEH12941.1 - 0.008 16.7 0.2 0.035 14.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 DUF605 PF04652.11 CEH12941.1 - 0.054 12.8 17.8 0.081 12.3 12.3 1.2 1 0 0 1 1 1 0 Vta1 like Tim17 PF02466.14 CEH12944.1 - 2.7e-26 92.0 6.8 3.3e-26 91.8 4.7 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ribosom_S12_S23 PF00164.20 CEH12945.1 - 1.3e-45 153.7 0.3 1.5e-45 153.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L14 PF00238.14 CEH12946.1 - 2e-34 117.9 0.0 2.2e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e KH_1 PF00013.24 CEH12947.1 - 1.2e-05 24.8 0.3 2.6e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 KH domain APG5 PF04106.7 CEH12948.1 - 1.7e-35 122.2 0.0 7.7e-35 120.1 0.0 1.8 1 1 0 1 1 1 1 Autophagy protein Apg5 Aldo_ket_red PF00248.16 CEH12951.1 - 1.2e-16 60.3 0.0 5.8e-09 35.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Myotub-related PF06602.9 CEH12953.1 - 6.5e-120 400.1 0.0 3.5e-119 397.7 0.0 1.9 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 CEH12953.1 - 0.026 14.7 0.0 0.08 13.1 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 CEH12953.1 - 0.034 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Vps36_ESCRT-II PF11605.3 CEH12953.1 - 0.036 13.8 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DPBB_1 PF03330.13 CEH12954.1 - 4.6e-06 26.5 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel BcrAD_BadFG PF01869.15 CEH12955.1 - 2.5e-16 59.8 0.7 1.8e-15 56.9 0.2 2.4 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family TRAUB PF08164.7 CEH12956.1 - 4.1e-21 74.8 0.0 1e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 CEH12956.1 - 1.9e-12 47.4 0.5 6e-12 45.8 0.4 1.9 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor F_bP_aldolase PF01116.15 CEH12957.1 - 3.5e-77 259.3 0.0 4.2e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Methyltransf_2 PF00891.13 CEH12960.1 - 7.5e-27 94.0 0.0 4.5e-26 91.5 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 CEH12960.1 - 0.0016 18.9 0.0 0.006 17.1 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH12960.1 - 0.0037 17.6 0.0 0.0085 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ANT PF03374.9 CEH12960.1 - 0.16 11.9 0.2 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain MIF4G PF02854.14 CEH12961.1 - 3.1e-28 98.6 0.9 2.2e-27 95.8 0.0 2.2 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CEH12961.1 - 5.9e-27 93.6 0.0 1.4e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 MA3 domain DEAD PF00270.24 CEH12962.1 - 4.8e-40 136.8 0.0 2.1e-38 131.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH12962.1 - 8.4e-27 92.8 0.0 2.5e-26 91.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CEH12962.1 - 4.8e-09 35.4 0.0 8.2e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CEH12962.1 - 7.6e-05 22.6 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CEH12962.1 - 0.024 14.3 0.0 0.082 12.6 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Helicase_C_2 PF13307.1 CEH12962.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Helicase C-terminal domain PAP2 PF01569.16 CEH12963.1 - 1.1e-09 38.0 6.2 3.4e-09 36.4 4.3 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 CEH12963.1 - 0.00021 20.8 6.1 0.027 13.9 0.5 2.7 2 1 0 2 2 2 2 PAP2 superfamily Sec10 PF07393.6 CEH12964.1 - 3.9e-235 782.3 0.0 4.8e-235 782.0 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF1759 PF03564.10 CEH12964.1 - 0.089 12.5 0.1 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) CTD_bind PF04818.8 CEH12964.1 - 0.19 11.9 0.1 0.88 9.8 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Drf_GBD PF06371.8 CEH12965.1 - 4.9e-07 29.2 0.0 3.6e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain PEMT PF04191.8 CEH12966.1 - 1.4e-30 105.5 6.4 1.4e-30 105.5 4.4 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase Cyanate_lyase PF02560.9 CEH12967.1 - 6.9e-34 115.2 0.0 1.1e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 CEH12967.1 - 0.0036 17.4 0.0 0.0054 16.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 CEH12967.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Asp PF00026.18 CEH12968.1 - 1.7e-41 142.5 3.9 8.3e-41 140.2 2.7 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CEH12968.1 - 0.0055 17.1 2.5 0.14 12.6 0.3 2.7 2 0 0 2 2 2 1 Aspartyl protease Rootletin PF15035.1 CEH12969.1 - 0.011 15.6 15.1 0.082 12.8 0.1 2.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Med9 PF07544.8 CEH12969.1 - 0.034 13.8 3.9 0.17 11.6 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3410 PF11890.3 CEH12969.1 - 0.07 12.7 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) KLRAQ PF10205.4 CEH12969.1 - 0.14 12.1 12.8 0.048 13.6 1.2 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein IncA PF04156.9 CEH12969.1 - 5 6.6 23.1 7.2 6.1 1.8 2.3 2 0 0 2 2 2 0 IncA protein 2OG-FeII_Oxy_2 PF13532.1 CEH12970.1 - 1.3e-09 38.1 0.0 5e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 CEH12971.1 - 1.9e-23 82.5 0.0 2.4e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 CEH12972.1 - 1.3e-19 69.9 0.0 2e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEH12972.1 - 0.085 13.8 0.1 0.17 12.8 0.1 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain YXWGXW PF12779.2 CEH12972.1 - 0.09 12.6 0.7 0.17 11.7 0.5 1.5 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) ICE2 PF08426.5 CEH12974.1 - 8.4e-47 159.6 7.5 3.5e-27 95.0 0.1 2.1 2 0 0 2 2 2 2 ICE2 Abhydrolase_6 PF12697.2 CEH12975.1 - 3.1e-11 43.6 0.7 3e-08 33.8 0.2 3.8 4 2 0 4 4 4 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH12975.1 - 8.7e-08 31.9 0.1 3.1e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH12975.1 - 8.9e-07 28.7 1.3 0.013 15.3 0.1 2.8 3 0 0 3 3 3 2 Alpha/beta hydrolase family His_Phos_2 PF00328.17 CEH12980.1 - 9.6e-16 58.0 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) G-patch PF01585.18 CEH12981.1 - 4.2e-12 45.6 1.7 8.1e-12 44.7 1.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CEH12981.1 - 0.00052 19.8 0.1 0.00052 19.8 0.1 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site zf-C2H2_jaz PF12171.3 CEH12981.1 - 0.0091 16.1 1.0 0.015 15.4 0.7 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEH12981.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CEH12981.1 - 0.13 12.6 0.5 0.25 11.7 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Myb_DNA-bind_6 PF13921.1 CEH12982.1 - 2.7e-05 24.1 0.0 5.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEH12982.1 - 0.0011 19.0 0.3 0.0077 16.2 0.2 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Pap_E4 PF02711.9 CEH12982.1 - 0.3 11.9 1.2 0.41 11.4 0.8 1.2 1 0 0 1 1 1 0 E4 protein Myb_DNA-binding PF00249.26 CEH12983.1 - 0.00055 19.9 0.2 0.00094 19.1 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH12983.1 - 0.0025 17.8 0.1 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain PGC7_Stella PF15549.1 CEH12983.1 - 0.016 15.2 0.3 0.02 14.8 0.1 1.3 1 1 0 1 1 1 0 PGC7/Stella/Dppa3 domain Presenilin PF01080.12 CEH12983.1 - 0.076 11.8 0.2 0.078 11.7 0.1 1.0 1 0 0 1 1 1 0 Presenilin Myb_DNA-binding PF00249.26 CEH12984.1 - 0.00074 19.5 0.0 0.0019 18.2 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH12984.1 - 0.002 18.2 0.1 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain RR_TM4-6 PF06459.7 CEH12984.1 - 0.072 12.9 1.3 0.1 12.5 0.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.9 CEH12984.1 - 0.14 11.6 3.0 0.14 11.6 2.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pap_E4 PF02711.9 CEH12984.1 - 8.9 7.2 7.3 31 5.4 5.0 1.9 1 1 0 1 1 1 0 E4 protein Myb_DNA-binding PF00249.26 CEH12985.1 - 0.0075 16.3 0.1 0.018 15.0 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Ndc1_Nup PF09531.5 CEH12985.1 - 0.18 10.1 5.6 0.2 10.0 3.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ORC6 PF05460.8 CEH12985.1 - 0.85 8.6 11.7 1.4 7.9 8.1 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TMEM247 PF15444.1 CEH12985.1 - 4.9 6.9 8.2 6.3 6.5 5.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Pneumo_att_G PF05539.6 CEH12985.1 - 6.2 6.0 12.7 8.1 5.7 8.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Myb_DNA-binding PF00249.26 CEH12986.1 - 0.0025 17.8 0.1 0.0066 16.4 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH12986.1 - 0.084 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ndc1_Nup PF09531.5 CEH12986.1 - 0.46 8.8 4.6 0.5 8.7 3.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMEM247 PF15444.1 CEH12986.1 - 9.5 5.9 7.6 12 5.6 5.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 TruB_N PF01509.13 CEH12987.1 - 4.4e-47 159.9 0.0 1.9e-38 131.9 0.0 2.1 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) Toprim_C_rpt PF13368.1 CEH12991.1 - 0.16 12.4 2.5 0.37 11.2 1.7 1.6 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat Hydrolase_6 PF13344.1 CEH12992.1 - 0.0083 15.9 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 CEH12993.1 - 1.7e-17 63.1 0.0 3.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Thi4 PF01946.12 CEH12995.1 - 2.8e-87 291.6 0.1 6.5e-87 290.4 0.0 1.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 CEH12995.1 - 3.4e-12 45.9 0.5 6.6e-08 31.8 0.8 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEH12995.1 - 1.7e-06 27.9 1.3 4.5e-06 26.5 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CEH12995.1 - 1.9e-06 27.0 0.6 4.6e-06 25.7 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 CEH12995.1 - 1e-05 25.3 1.5 0.0003 20.5 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 CEH12995.1 - 3.4e-05 22.8 1.1 0.00039 19.3 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CEH12995.1 - 5.5e-05 23.1 0.1 8.4e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEH12995.1 - 0.00036 19.1 0.3 0.00067 18.2 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 CEH12995.1 - 0.0026 17.8 0.6 0.012 15.7 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEH12995.1 - 0.0029 16.7 0.3 0.0043 16.1 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CEH12995.1 - 0.011 14.3 0.2 0.017 13.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 CEH12995.1 - 0.073 11.9 0.1 0.23 10.2 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Abhydrolase_3 PF07859.8 CEH12996.1 - 9.6e-30 103.7 0.0 1.1e-21 77.3 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CEH12996.1 - 5e-08 31.9 0.0 1.4e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CEH12996.1 - 0.00038 20.2 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEH12996.1 - 0.017 14.3 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Mak10 PF04112.8 CEH12997.1 - 8.6e-36 122.6 0.0 1.5e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase AlaDh_PNT_N PF05222.10 CEH12998.1 - 1.3e-26 93.1 0.0 4.1e-26 91.6 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CEH12998.1 - 9e-06 25.3 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain WHIM2 PF15613.1 CEH12999.1 - 0.0016 18.2 0.0 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 DUF4618 PF15397.1 CEH12999.1 - 0.01 15.2 8.5 0.11 11.7 2.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) DUF1640 PF07798.6 CEH12999.1 - 0.56 10.2 9.6 3 7.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) AreA_N PF07573.6 CEH13001.1 - 0.38 11.3 3.4 0.21 12.1 0.7 1.9 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus VHS PF00790.14 CEH13003.1 - 8.1e-15 54.6 0.0 1.3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 VHS domain YdfA_immunity PF12127.3 CEH13003.1 - 0.45 9.3 2.2 0.84 8.4 1.5 1.3 1 0 0 1 1 1 0 SigmaW regulon antibacterial Ifi-6-16 PF06140.8 CEH13004.1 - 5.2e-09 35.7 3.0 0.0016 18.1 0.1 2.8 2 2 0 2 2 2 2 Interferon-induced 6-16 family Acetyltransf_4 PF13420.1 CEH13004.1 - 0.019 14.8 0.1 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF934 PF06073.7 CEH13004.1 - 0.025 14.2 0.2 3.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF934) Toxin_62 PF15540.1 CEH13004.1 - 0.072 13.1 0.3 5.8 7.0 0.0 2.3 1 1 1 2 2 2 0 Putative toxin 62 RNA_pol PF00940.14 CEH13005.1 - 8.9e-187 620.5 0.1 2.5e-147 490.5 0.0 2.2 1 1 1 2 2 2 2 DNA-dependent RNA polymerase RPOL_N PF14700.1 CEH13005.1 - 4.8e-68 229.7 4.8 9.1e-67 225.5 3.3 2.3 1 1 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 CEH13005.1 - 1.6e-05 24.7 0.0 0.0081 16.1 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 CEH13005.1 - 0.067 13.4 0.1 8.1 7.0 0.0 3.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain PPR PF01535.15 CEH13005.1 - 0.11 12.4 0.4 2.7 8.1 0.0 2.9 3 0 0 3 3 3 0 PPR repeat CTP_transf_1 PF01148.15 CEH13006.1 - 3e-69 233.5 20.3 5.4e-69 232.7 14.1 1.4 1 1 0 1 1 1 1 Cytidylyltransferase family OAD_gamma PF04277.8 CEH13006.1 - 2.3 8.6 0.0 2.3 8.6 0.0 4.4 4 1 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain SRP54 PF00448.17 CEH13007.1 - 2.9e-75 252.0 0.4 4.6e-75 251.3 0.3 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CEH13007.1 - 1.5e-22 79.8 0.7 1.5e-22 79.8 0.5 4.2 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.14 CEH13007.1 - 1e-09 38.3 0.3 1e-09 38.3 0.2 1.8 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 CEH13007.1 - 3.3e-06 27.0 0.0 6.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CEH13007.1 - 7e-06 25.5 0.3 3.1e-05 23.5 0.2 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 CEH13007.1 - 0.00012 21.5 0.2 0.0007 19.0 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CEH13007.1 - 0.00013 20.8 1.6 0.00093 18.0 0.3 2.6 1 1 1 2 2 2 1 ArgK protein MobB PF03205.9 CEH13007.1 - 0.00084 19.0 0.1 0.0017 18.0 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 CEH13007.1 - 0.0026 17.7 0.0 0.41 10.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 CEH13007.1 - 0.012 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain TrwB_AAD_bind PF10412.4 CEH13007.1 - 0.014 14.0 0.1 0.69 8.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 CEH13007.1 - 0.021 14.8 0.1 0.066 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain VirE PF05272.6 CEH13007.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E SRPRB PF09439.5 CEH13007.1 - 0.025 13.8 0.2 0.93 8.6 0.1 2.6 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit APS_kinase PF01583.15 CEH13007.1 - 0.034 13.8 0.3 0.08 12.6 0.0 1.7 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_30 PF13604.1 CEH13007.1 - 0.038 13.5 1.5 0.059 12.9 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CEH13007.1 - 0.039 14.7 0.0 0.074 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CEH13007.1 - 0.081 12.4 0.2 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 CEH13007.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Biotin_lipoyl_2 PF13533.1 CEH13007.1 - 0.11 12.1 0.2 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like Zn_clus PF00172.13 CEH13010.1 - 4e-05 23.4 6.9 8.6e-05 22.3 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 CEH13010.1 - 0.029 14.0 2.6 0.037 13.7 0.9 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Sugar_tr PF00083.19 CEH13012.1 - 8.4e-31 107.0 25.9 1.2e-23 83.3 4.8 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 CEH13012.1 - 1.6e-25 89.5 34.9 1.6e-25 89.5 24.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SET PF00856.23 CEH13013.1 - 6.4e-13 49.3 0.4 1.3e-11 45.0 0.0 2.9 3 1 0 3 3 3 1 SET domain TraB PF01963.12 CEH13013.1 - 0.048 13.1 0.3 0.08 12.3 0.2 1.3 1 0 0 1 1 1 0 TraB family SAF PF08666.7 CEH13013.1 - 0.048 14.0 0.0 7.1 7.1 0.0 2.5 2 0 0 2 2 2 0 SAF domain DUF1780 PF08682.5 CEH13013.1 - 0.14 11.6 0.6 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1780) Aa_trans PF01490.13 CEH13014.1 - 1.4e-19 69.9 16.2 2.6e-19 69.0 11.2 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PS_Dcarbxylase PF02666.10 CEH13015.1 - 2.7e-47 160.7 0.0 6.9e-47 159.3 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase DUF106 PF01956.11 CEH13016.1 - 0.24 10.9 3.4 0.5 9.8 2.4 1.7 1 1 0 1 1 1 0 Integral membrane protein DUF106 STAT_alpha PF01017.15 CEH13016.1 - 1.1 8.9 9.5 0.5 10.0 3.7 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain RRF PF01765.14 CEH13016.1 - 2.5 7.5 5.4 0.28 10.6 0.9 1.5 2 0 0 2 2 2 0 Ribosome recycling factor THOC7 PF05615.8 CEH13016.1 - 4.5 7.5 9.2 29 4.9 6.3 2.3 1 1 0 1 1 1 0 Tho complex subunit 7 Ribonuclease PF00545.15 CEH13017.1 - 5.6e-14 51.9 0.9 7.1e-14 51.6 0.6 1.2 1 0 0 1 1 1 1 ribonuclease Amidohydro_4 PF13147.1 CEH13017.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase Exo_endo_phos PF03372.18 CEH13018.1 - 3.2e-12 46.9 1.8 5.7e-12 46.0 1.2 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Asp PF00026.18 CEH13019.1 - 1.1e-73 248.2 1.1 3.6e-73 246.5 0.8 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEH13019.1 - 6.5e-06 26.1 0.4 2.7e-05 24.1 0.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DUF3106 PF11304.3 CEH13019.1 - 0.2 12.0 2.5 0.31 11.4 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) adh_short PF00106.20 CEH13020.1 - 7.8e-21 74.7 0.0 1.1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH13020.1 - 4.4e-09 36.4 0.0 1e-08 35.3 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH13020.1 - 0.00089 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CEH13020.1 - 0.0035 16.5 0.0 0.0046 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 CEH13020.1 - 0.012 15.6 0.2 0.072 13.0 0.1 2.5 1 1 0 1 1 1 0 NADH(P)-binding Amidohydro_3 PF07969.6 CEH13021.1 - 5.4e-46 157.6 0.3 2e-33 116.1 0.2 2.1 1 1 1 2 2 2 2 Amidohydrolase family Peptidase_C65 PF10275.4 CEH13024.1 - 1e-42 146.1 0.0 6.5e-21 74.7 0.0 2.1 1 1 1 2 2 2 2 Peptidase C65 Otubain OTU PF02338.14 CEH13024.1 - 4.6e-06 27.2 0.0 8.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Vps35 PF03635.12 CEH13026.1 - 1.6e-92 311.0 0.8 1.8e-92 310.7 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Vps35 PF03635.12 CEH13027.1 - 6.4e-117 391.6 0.0 8.2e-117 391.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 HMG_box PF00505.14 CEH13028.1 - 2.1e-14 53.5 0.7 2.1e-14 53.5 0.5 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEH13028.1 - 2.1e-10 40.7 1.1 2.1e-10 40.7 0.8 1.5 1 1 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 CEH13028.1 - 0.055 13.1 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain Pantoate_ligase PF02569.10 CEH13029.1 - 3.1e-78 262.3 0.0 2.5e-77 259.3 0.0 1.9 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase 4HBT PF03061.17 CEH13030.1 - 0.022 14.8 0.2 0.06 13.4 0.1 1.7 1 0 0 1 1 1 0 Thioesterase superfamily 4HBT PF03061.17 CEH13031.1 - 0.052 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Apt1 PF10351.4 CEH13033.1 - 3.4e-112 375.6 0.0 3.4e-112 375.6 0.0 3.9 5 0 0 5 5 5 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 CEH13033.1 - 3.3e-86 289.5 1.1 7.8e-86 288.3 0.8 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 CEH13033.1 - 5.8e-42 143.2 0.0 1e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CEH13033.1 - 1.9e-32 112.2 0.0 3.4e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CEH13033.1 - 5.9e-19 68.4 0.0 2e-18 66.7 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.4 CEH13033.1 - 0.00022 19.0 0.1 0.00044 18.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Mg_trans_NIPA PF05653.9 CEH13035.1 - 8.5e-62 208.7 0.0 1.4e-58 198.2 0.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 CEH13035.1 - 6.3e-06 26.3 10.3 1.6e-05 25.0 0.2 3.2 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 CEH13035.1 - 0.00011 22.2 1.4 0.00011 22.2 1.0 3.4 2 1 1 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 CEH13035.1 - 0.025 13.4 0.0 0.065 12.0 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) AAA PF00004.24 CEH13036.1 - 4.6e-61 204.8 0.0 3.2e-45 153.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEH13036.1 - 3.3e-06 27.9 0.0 0.0091 16.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEH13036.1 - 7.9e-06 26.0 0.2 0.0063 16.6 0.0 3.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEH13036.1 - 9.5e-06 25.7 9.3 0.0093 15.9 0.1 4.3 3 1 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.9 CEH13036.1 - 1.5e-05 24.7 0.1 0.018 14.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CEH13036.1 - 3.6e-05 22.9 0.0 0.0058 15.6 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CEH13036.1 - 0.00014 21.7 0.0 0.09 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CEH13036.1 - 0.00023 20.6 1.4 0.0039 16.6 0.1 3.3 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 CEH13036.1 - 0.00027 20.6 2.9 0.0071 16.0 0.0 3.5 3 0 0 3 3 3 1 Part of AAA domain AAA_28 PF13521.1 CEH13036.1 - 0.00041 20.3 0.1 0.2 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CEH13036.1 - 0.00047 20.0 0.3 0.21 11.4 0.0 4.0 4 0 0 4 4 4 1 AAA domain DUF815 PF05673.8 CEH13036.1 - 0.00066 18.6 0.0 1.7 7.5 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 CEH13036.1 - 0.00098 18.5 0.0 0.0034 16.8 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 CEH13036.1 - 0.0017 17.1 0.0 0.033 12.9 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus KaiC PF06745.8 CEH13036.1 - 0.0021 17.2 0.1 0.0052 15.9 0.0 1.6 2 0 0 2 2 1 1 KaiC Sigma54_activat PF00158.21 CEH13036.1 - 0.0027 17.2 0.0 1.8 8.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_2 PF07724.9 CEH13036.1 - 0.0042 16.9 0.0 0.016 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.12 CEH13036.1 - 0.01 14.7 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.16 CEH13036.1 - 0.014 14.5 0.3 0.049 12.7 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CEH13036.1 - 0.018 14.7 1.1 3.2 7.3 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.1 CEH13036.1 - 0.019 15.2 0.0 0.17 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CEH13036.1 - 0.019 14.1 0.0 0.082 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 CEH13036.1 - 0.021 14.9 0.0 0.096 12.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Sigma54_activ_2 PF14532.1 CEH13036.1 - 0.023 14.7 0.0 3 7.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 CEH13036.1 - 0.047 13.2 0.2 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CEH13036.1 - 0.2 10.5 0.0 1.5 7.6 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain IL15 PF02372.10 CEH13036.1 - 0.35 10.6 0.0 0.78 9.5 0.0 1.5 1 0 0 1 1 1 0 Interleukin 15 IATP PF04568.7 CEH13037.1 - 0.002 18.1 1.8 0.0023 17.9 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP TMF_DNA_bd PF12329.3 CEH13037.1 - 0.0044 16.7 2.6 0.0056 16.4 1.8 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding PspA_IM30 PF04012.7 CEH13037.1 - 0.0072 15.6 0.6 0.008 15.5 0.4 1.0 1 0 0 1 1 1 1 PspA/IM30 family KLRAQ PF10205.4 CEH13037.1 - 0.014 15.4 0.4 0.017 15.1 0.3 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Phage_lysis PF03245.8 CEH13037.1 - 0.02 14.8 0.9 0.021 14.7 0.6 1.1 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein DivIC PF04977.10 CEH13037.1 - 0.13 11.7 3.5 0.15 11.5 2.4 1.2 1 0 0 1 1 1 0 Septum formation initiator Pox_A_type_inc PF04508.7 CEH13037.1 - 0.14 12.0 2.7 0.21 11.4 1.9 1.3 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat M PF02370.11 CEH13037.1 - 6.3 7.5 8.2 1.2 9.6 2.4 2.0 2 0 0 2 2 2 0 M protein repeat ATP_sub_h PF10775.4 CEH13038.1 - 1.2e-23 82.6 1.2 1.7e-23 82.0 0.8 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 CEH13038.1 - 0.0071 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 NUFIP1 PF10453.4 CEH13038.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) FYVE PF01363.16 CEH13039.1 - 0.018 14.9 4.0 0.035 13.9 2.8 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4_2 PF13923.1 CEH13039.1 - 0.48 10.5 10.9 0.85 9.6 7.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Erg28 PF03694.8 CEH13040.1 - 2.6e-34 117.5 0.9 3.1e-34 117.3 0.6 1.1 1 0 0 1 1 1 1 Erg28 like protein dUTPase PF00692.14 CEH13040.1 - 0.15 11.5 0.1 0.25 10.8 0.1 1.4 1 1 0 1 1 1 0 dUTPase LIM PF00412.17 CEH13042.1 - 4.9e-20 71.3 15.7 4.2e-11 42.7 2.7 2.7 2 1 0 2 2 2 2 LIM domain DUF164 PF02591.10 CEH13042.1 - 2.4 8.0 7.6 1.4 8.7 0.0 3.4 4 0 0 4 4 4 0 Putative zinc ribbon domain Ribosomal_S4 PF00163.14 CEH13043.1 - 1.7e-27 95.6 1.0 2.7e-27 94.9 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CEH13043.1 - 1.2e-11 43.8 0.9 1.2e-11 43.8 0.6 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 CEH13044.1 - 3.1e-15 55.7 3.4 9.7e-14 50.9 2.2 2.0 2 0 0 2 2 2 2 Ribosomal protein L21e Got1 PF04178.7 CEH13046.1 - 5.6e-10 39.3 0.0 5.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family CUE PF02845.11 CEH13048.1 - 1.8e-07 30.5 0.0 3.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.6 CEH13048.1 - 0.032 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) ELK PF03789.8 CEH13048.1 - 0.3 10.9 1.0 0.57 10.0 0.7 1.4 1 0 0 1 1 1 0 ELK domain Rhodanese PF00581.15 CEH13050.1 - 0.017 15.4 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 Rhodanese-like domain DSPc PF00782.15 CEH13051.1 - 3e-06 26.8 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Acetyltransf_2 PF00797.12 CEH13053.1 - 4.6e-27 95.1 1.9 1.5e-23 83.6 0.2 2.2 2 0 0 2 2 2 2 N-acetyltransferase RhoGEF PF00621.15 CEH13055.1 - 4.7e-39 134.1 0.0 6.5e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 CEH13055.1 - 1.3e-19 69.8 5.9 2.3e-19 69.0 4.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 CEH13055.1 - 2.7e-07 30.7 0.0 8.2e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 PH domain Mcp5_PH PF12814.2 CEH13055.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology FYVE_2 PF02318.11 CEH13055.1 - 0.057 13.3 4.2 0.11 12.3 2.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger YbgS PF13985.1 CEH13056.1 - 0.13 12.1 2.4 0.15 11.9 1.7 1.3 1 1 0 1 1 1 0 YbgS-like protein GTP_EFTU PF00009.22 CEH13057.1 - 2.3e-38 131.5 0.0 3.8e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CEH13057.1 - 5.3e-38 128.9 0.2 1.4e-37 127.6 0.1 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CEH13057.1 - 2.1e-10 40.5 0.6 8.4e-10 38.6 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEH13057.1 - 0.0024 17.8 0.0 0.0058 16.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CEH13057.1 - 0.0076 16.0 0.3 0.089 12.6 0.2 2.7 1 1 0 1 1 1 1 Dynamin family PduV-EutP PF10662.4 CEH13057.1 - 0.24 10.9 3.0 10 5.5 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Mucin PF01456.12 CEH13058.1 - 0.016 15.0 1.3 0.019 14.7 0.9 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein HLH PF00010.21 CEH13059.1 - 4.3e-08 32.7 0.0 1.3e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 CEH13060.1 - 1.8e-54 184.6 0.2 9.6e-35 119.9 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH13060.1 - 3.7e-23 81.9 0.3 1.9e-15 56.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEH13060.1 - 0.0024 16.8 0.0 0.016 14.1 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 CEH13060.1 - 0.046 13.4 7.7 0.072 12.8 0.1 3.3 2 1 0 3 3 3 0 Phosphotransferase enzyme family DUF1615 PF07759.7 CEH13060.1 - 0.22 10.2 0.3 0.34 9.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) SDH_alpha PF03313.10 CEH13061.1 - 8.6e-87 290.7 1.4 8.6e-87 290.7 1.0 2.3 2 1 0 2 2 2 1 Serine dehydratase alpha chain SDH_beta PF03315.10 CEH13061.1 - 2.1e-47 161.1 0.0 5.4e-47 159.7 0.0 1.7 1 0 0 1 1 1 1 Serine dehydratase beta chain OPT PF03169.10 CEH13062.1 - 3.4e-150 501.4 39.2 3.9e-150 501.2 27.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BofA PF07441.6 CEH13062.1 - 0.48 10.4 12.9 0.1 12.5 4.9 2.9 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA DUF1242 PF06842.7 CEH13063.1 - 1e-17 63.3 0.8 1.3e-17 62.9 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) HEM4 PF02602.10 CEH13064.1 - 5.4e-25 87.9 0.0 3.1e-17 62.6 0.0 2.4 2 0 0 2 2 2 2 Uroporphyrinogen-III synthase HemD Cyclin_N PF00134.18 CEH13066.1 - 4.3e-36 123.2 0.1 7.4e-36 122.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CEH13066.1 - 1.6e-07 31.2 0.0 1.6e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain LAG1-DNAbind PF09271.6 CEH13067.1 - 3.2e-16 60.0 0.0 2.6e-15 57.1 0.0 2.2 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 CEH13067.1 - 9e-15 54.7 0.0 2.4e-14 53.3 0.0 1.6 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain Syja_N PF02383.13 CEH13072.1 - 1.7e-90 303.0 0.1 2.1e-90 302.7 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain RRM_1 PF00076.17 CEH13073.1 - 3.5e-11 42.5 0.0 1.1e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH13073.1 - 2.8e-08 33.6 0.0 4.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH13073.1 - 8.8e-06 25.4 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PDT PF00800.13 CEH13074.1 - 1.2e-25 90.1 0.0 6.6e-25 87.7 0.0 2.0 1 1 0 1 1 1 1 Prephenate dehydratase Coq4 PF05019.8 CEH13075.1 - 1.5e-71 239.8 0.0 8.6e-61 204.6 0.0 2.1 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Secretin_N_2 PF07655.8 CEH13075.1 - 0.0031 17.8 1.0 0.0031 17.8 0.7 2.0 2 0 0 2 2 2 1 Secretin N-terminal domain BCIP PF13862.1 CEH13076.1 - 5.8e-37 127.0 0.0 6.9e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF765 PF05570.6 CEH13076.1 - 0.13 12.2 0.8 0.25 11.3 0.5 1.5 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) DNA_ligase_OB_2 PF14743.1 CEH13077.1 - 1.6e-15 56.5 0.3 3.4e-15 55.4 0.0 1.8 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 CEH13077.1 - 9.2e-08 31.6 0.0 1.7e-06 27.5 0.0 2.3 1 1 1 2 2 2 1 ATP dependent DNA ligase domain SWIM PF04434.12 CEH13077.1 - 0.053 13.0 0.3 0.11 11.9 0.2 1.5 1 0 0 1 1 1 0 SWIM zinc finger DUF3510 PF12022.3 CEH13079.1 - 1.9 8.6 3.8 1.8e+02 2.2 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3510) Lum_binding PF00677.12 CEH13080.1 - 3.8e-28 97.2 0.0 8.8e-18 63.9 0.0 4.0 3 2 0 3 3 3 3 Lumazine binding domain Actin PF00022.14 CEH13081.1 - 1.2e-31 109.5 0.0 1.6e-28 99.2 0.0 2.9 3 0 0 3 3 3 2 Actin MreB_Mbl PF06723.8 CEH13081.1 - 1.5e-05 23.7 0.0 2.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein F5_F8_type_C PF00754.20 CEH13083.1 - 2.1e-09 37.3 0.1 5.5e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain Trehalase PF01204.13 CEH13083.1 - 0.0012 17.5 1.1 0.0012 17.5 0.7 1.5 2 0 0 2 2 2 1 Trehalase Glyco_hydro_63 PF03200.11 CEH13083.1 - 0.0015 16.5 6.2 0.063 11.1 4.3 2.1 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Bac_rhamnosid PF05592.6 CEH13083.1 - 0.0028 15.9 0.6 0.0048 15.1 0.4 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase SBF PF01758.11 CEH13086.1 - 5e-45 153.2 13.8 5e-45 153.2 9.6 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family Tim44 PF04280.10 CEH13087.1 - 2.7e-30 105.3 0.0 6.5e-30 104.0 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain DUF3435 PF11917.3 CEH13087.1 - 0.023 13.4 0.1 0.034 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Mis12 PF05859.7 CEH13089.1 - 5.3e-19 68.4 0.3 2e-18 66.5 0.2 1.9 1 1 0 1 1 1 1 Mis12 protein Rep_fac_C PF08542.6 CEH13090.1 - 5.7e-20 71.0 0.1 2.8e-19 68.8 0.0 2.2 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CEH13090.1 - 3e-13 49.7 0.0 4.6e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CEH13090.1 - 9.1e-06 25.9 0.1 2.4e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEH13090.1 - 7e-05 22.9 0.3 0.00047 20.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CEH13090.1 - 0.0026 17.6 0.2 0.0087 15.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain SNF2_N PF00176.18 CEH13090.1 - 0.013 14.2 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain RuvB_N PF05496.7 CEH13090.1 - 0.014 14.4 0.6 2.4 7.1 0.0 2.5 2 1 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 CEH13090.1 - 0.03 14.3 0.1 0.24 11.4 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.10 CEH13090.1 - 0.082 11.5 0.0 0.17 10.5 0.0 1.5 1 1 1 2 2 2 0 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 CEH13090.1 - 0.093 13.0 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 CEH13090.1 - 0.11 11.9 0.4 0.73 9.2 0.1 2.0 1 1 1 2 2 2 0 AAA-like domain Defensin_propep PF00879.13 CEH13091.1 - 0.18 11.8 1.0 0.45 10.5 0.7 1.7 1 0 0 1 1 1 0 Defensin propeptide Glyco_hydro_25 PF01183.15 CEH13092.1 - 6.5e-47 159.6 0.4 7.5e-47 159.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Nefa_Nip30_N PF10187.4 CEH13093.1 - 4.5 7.5 6.7 2.7 8.1 3.3 1.7 2 1 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 PAT1 PF09770.4 CEH13094.1 - 3 5.9 11.2 3.8 5.6 7.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CEH13094.1 - 6.2 6.1 16.6 6.6 6.0 11.5 1.1 1 0 0 1 1 1 0 Vta1 like DUF2410 PF10307.4 CEH13095.1 - 0.015 14.6 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Hypothetical protein (DUF2410) YtxH PF12732.2 CEH13095.1 - 0.079 13.3 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 YtxH-like protein DUF2380 PF09533.5 CEH13098.1 - 0.046 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) MFS_1 PF07690.11 CEH13100.1 - 6.2e-25 87.6 20.9 6.2e-25 87.6 14.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 CEH13100.1 - 0.0049 16.3 3.8 0.067 12.6 1.5 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 CD34_antigen PF06365.7 CEH13100.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Arylsulfotran_2 PF14269.1 CEH13101.1 - 1.7e-53 181.7 10.7 1.3e-46 159.1 2.9 2.1 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 CEH13101.1 - 2.3e-11 42.9 6.4 3.6e-11 42.2 4.4 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) V_ATPase_I PF01496.14 CEH13103.1 - 0.52 8.1 5.3 0.68 7.7 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OTU PF02338.14 CEH13104.1 - 0.0014 19.1 0.0 0.0032 18.0 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Acyl_transf_1 PF00698.16 CEH13107.1 - 3.1e-07 30.0 10.6 0.0003 20.2 0.0 4.1 4 0 0 4 4 4 3 Acyl transferase domain Serglycin PF04360.7 CEH13107.1 - 0.12 12.0 10.4 2.6 7.7 0.6 3.2 2 0 0 2 2 2 0 Serglycin Flavoprotein PF02441.14 CEH13109.1 - 5e-41 139.3 0.5 1.4e-40 137.9 0.1 2.1 2 0 0 2 2 2 1 Flavoprotein VPS9 PF02204.13 CEH13109.1 - 2.2e-18 66.1 0.0 6.2e-18 64.7 0.0 1.7 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain NDUFB10 PF10249.4 CEH13110.1 - 0.016 15.3 0.1 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 DUF3562 PF12085.3 CEH13110.1 - 0.098 12.5 1.2 9.6 6.1 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3562) UIM PF02809.15 CEH13111.1 - 0.0029 17.0 0.1 0.0086 15.5 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Herpes_LAMP2 PF06126.6 CEH13111.1 - 4.9 5.4 0.5 28 2.9 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus Latent membrane protein 2 RCC1 PF00415.13 CEH13113.1 - 2.9e-10 40.1 11.9 0.025 14.7 0.1 8.0 9 0 0 9 9 9 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CEH13113.1 - 1.8e-05 24.1 16.1 0.00029 20.3 0.0 6.5 6 1 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CEH13115.1 - 0.098 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 BTB/POZ domain Abhydrolase_6 PF12697.2 CEH13116.1 - 7.7e-22 78.2 0.0 1.4e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH13116.1 - 3.8e-11 42.9 1.5 2e-10 40.6 1.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH13116.1 - 2.7e-06 27.1 0.1 2.4e-05 23.9 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEH13116.1 - 0.029 13.5 1.0 1.3 8.2 0.2 3.0 1 1 3 4 4 4 0 Prolyl oligopeptidase family DLH PF01738.13 CEH13116.1 - 0.051 12.8 1.0 21 4.3 0.2 3.0 2 1 1 3 3 3 0 Dienelactone hydrolase family RRM_1 PF00076.17 CEH13117.1 - 6.6e-41 137.8 0.0 2.4e-14 52.7 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH13117.1 - 8.9e-33 112.0 0.0 5.1e-12 45.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH13117.1 - 6.3e-13 48.3 0.0 4.5e-06 26.4 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_16 PF13432.1 CEH13117.1 - 0.045 14.4 2.8 0.14 12.8 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF500 PF04366.7 CEH13118.1 - 6.9e-37 125.7 0.3 1.9e-36 124.3 0.2 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_9 PF14604.1 CEH13118.1 - 9e-12 44.3 0.0 2e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEH13118.1 - 3.9e-11 42.1 0.0 7.8e-11 41.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEH13118.1 - 3.5e-10 39.2 0.1 6.4e-09 35.1 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain IncA PF04156.9 CEH13119.1 - 0.0032 17.0 2.6 0.0048 16.5 1.8 1.2 1 0 0 1 1 1 1 IncA protein DUF972 PF06156.8 CEH13119.1 - 0.074 13.4 4.9 0.2 12.0 3.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 CEH13119.1 - 0.078 12.0 2.9 0.12 11.3 2.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 XkdW PF09636.5 CEH13119.1 - 0.2 11.5 1.5 0.38 10.6 1.1 1.5 1 1 0 1 1 1 0 XkdW protein Herpes_BLRF2 PF05812.7 CEH13119.1 - 0.53 10.0 5.4 0.12 12.1 0.5 2.3 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 CEH13119.1 - 1.8 8.5 7.2 2.1 8.3 1.6 2.4 1 1 1 2 2 2 0 bZIP transcription factor CCDC-167 PF15188.1 CEH13119.1 - 3 7.8 6.8 12 5.8 2.7 2.8 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DivIC PF04977.10 CEH13119.1 - 5.6 6.5 6.3 6.5 6.3 1.5 2.3 1 1 1 2 2 2 0 Septum formation initiator Vezatin PF12632.2 CEH13120.1 - 0.017 14.1 0.0 0.03 13.4 0.0 1.5 1 1 0 1 1 1 0 Mysoin-binding motif of peroxisomes Enkurin PF13864.1 CEH13120.1 - 0.076 13.2 0.4 0.13 12.5 0.3 1.3 1 0 0 1 1 1 0 Calmodulin-binding NTR2 PF15458.1 CEH13120.1 - 0.13 11.4 2.3 0.29 10.3 1.3 1.7 1 1 0 1 1 1 0 Nineteen complex-related protein 2 Vac_Fusion PF02346.11 CEH13120.1 - 0.33 10.3 2.4 2.5 7.5 0.1 2.4 1 1 1 2 2 2 0 Chordopoxvirus fusion protein GSH-S_N PF02951.9 CEH13121.1 - 0.004 16.9 2.7 0.71 9.6 0.5 2.2 2 0 0 2 2 2 2 Prokaryotic glutathione synthetase, N-terminal domain IFT46_B_C PF12317.3 CEH13121.1 - 0.005 16.2 0.2 0.0059 16.0 0.2 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Phage_GP20 PF06810.6 CEH13121.1 - 0.047 13.1 0.5 0.055 12.9 0.3 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Enkurin PF13864.1 CEH13121.1 - 0.054 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Calmodulin-binding COG2 PF06148.6 CEH13121.1 - 0.31 10.8 2.0 0.47 10.3 1.4 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2077 PF09850.4 CEH13122.1 - 0.019 14.3 0.1 0.025 13.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) SLX9 PF15341.1 CEH13123.1 - 0.021 15.2 0.7 0.059 13.8 0.5 1.7 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 CENP-H PF05837.7 CEH13124.1 - 0.008 16.3 5.7 0.008 16.3 4.0 2.3 1 1 1 2 2 2 1 Centromere protein H (CENP-H) CAF-1_p150 PF11600.3 CEH13124.1 - 0.099 12.0 14.6 0.13 11.6 10.1 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Plasmid_stabil PF05016.9 CEH13124.1 - 0.27 11.6 3.7 0.32 11.3 0.5 2.5 2 1 1 3 3 3 0 Plasmid stabilisation system protein APG6 PF04111.7 CEH13124.1 - 3.7 6.4 13.7 5.9 5.8 9.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PSK_trans_fac PF07704.6 CEH13128.1 - 0.027 15.1 6.1 0.027 15.1 4.2 3.0 1 1 1 2 2 2 0 Rv0623-like transcription factor Peptidase_M10 PF00413.19 CEH13128.1 - 0.063 13.0 0.8 0.62 9.7 0.1 2.2 2 0 0 2 2 2 0 Matrixin DUF3685 PF12452.3 CEH13128.1 - 0.095 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) YlqD PF11068.3 CEH13128.1 - 0.29 11.1 7.1 0.49 10.4 5.0 1.3 1 0 0 1 1 1 0 YlqD protein DDE_Tnp_IS66 PF03050.9 CEH13128.1 - 0.29 10.2 11.7 0.5 9.5 8.1 1.2 1 0 0 1 1 1 0 Transposase IS66 family LMP PF04778.7 CEH13131.1 - 0.00022 21.0 4.6 0.00037 20.2 3.2 1.2 1 0 0 1 1 1 1 LMP repeated region Hemerythrin PF01814.18 CEH13131.1 - 0.072 13.2 3.7 0.1 12.7 2.6 1.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain UPF0184 PF03670.8 CEH13133.1 - 0.029 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF869 PF05911.6 CEH13134.1 - 0.0027 16.0 26.6 0.072 11.3 8.3 2.2 1 1 1 2 2 2 2 Plant protein of unknown function (DUF869) GAS PF13851.1 CEH13134.1 - 1.4 8.0 33.1 1.1 8.3 9.8 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding UPF0449 PF15136.1 CEH13134.1 - 8.1 6.7 15.9 4.5 7.5 2.1 3.8 3 1 1 4 4 4 0 Uncharacterised protein family UPF0449 Tropomyosin_1 PF12718.2 CEH13134.1 - 9.1 6.1 40.0 2.6 7.8 6.5 3.7 1 1 3 4 4 4 0 Tropomyosin like Filo_VP35 PF02097.10 CEH13137.1 - 0.087 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 HALZ PF02183.13 CEH13138.1 - 0.62 9.8 21.0 0.19 11.4 0.4 4.7 4 1 0 4 4 4 0 Homeobox associated leucine zipper DivIVA PF05103.8 CEH13138.1 - 0.92 9.5 21.3 0.66 10.0 3.9 3.5 1 1 2 3 3 3 0 DivIVA protein TMF_DNA_bd PF12329.3 CEH13138.1 - 1.3 8.9 22.0 0.87 9.4 5.6 3.9 3 2 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DnaI_N PF07319.6 CEH13138.1 - 2.8 8.2 5.2 21 5.4 0.8 2.5 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus DUF972 PF06156.8 CEH13138.1 - 3.8 7.9 21.7 0.19 12.0 3.9 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF972) ERM PF00769.14 CEH13138.1 - 7.4 6.0 32.3 1.2 8.5 4.0 3.0 1 1 2 3 3 3 0 Ezrin/radixin/moesin family RHH_3 PF12651.2 CEH13139.1 - 0.07 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain RHH_1 PF01402.16 CEH13139.1 - 0.16 11.9 0.3 18 5.3 0.0 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Herpes_capsid PF06112.6 CEH13139.1 - 3.1 7.8 9.0 4.4 7.3 6.2 1.4 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein DUF1043 PF06295.7 CEH13140.1 - 0.018 14.6 0.5 0.018 14.6 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF29 PF01724.11 CEH13140.1 - 0.018 14.8 1.1 0.023 14.5 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF29 DUF2597 PF10772.4 CEH13140.1 - 0.074 12.9 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) Spc7 PF08317.6 CEH13140.1 - 0.2 10.2 4.7 0.4 9.3 3.3 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 CEH13140.1 - 0.34 10.4 2.2 0.47 9.9 1.5 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HBS1_N PF08938.5 CEH13140.1 - 0.6 10.2 3.7 8.7 6.5 0.5 2.3 1 1 0 2 2 2 0 HBS1 N-terminus YscO PF07321.7 CEH13140.1 - 1 9.1 14.6 3 7.6 10.1 1.6 1 1 0 1 1 1 0 Type III secretion protein YscO DASH_Spc19 PF08287.6 CEH13140.1 - 2.6 7.6 5.6 3.6 7.1 3.9 1.1 1 0 0 1 1 1 0 Spc19 DUF3584 PF12128.3 CEH13140.1 - 3.9 4.6 11.3 4.6 4.4 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF484 PF04340.7 CEH13140.1 - 4.2 6.7 8.0 6.9 6.0 5.5 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF484 Atg14 PF10186.4 CEH13140.1 - 6.9 5.5 6.5 11 4.7 4.4 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 CEH13141.1 - 7.1e-06 25.7 80.5 0.052 13.3 8.0 5.8 3 2 2 5 5 5 4 TATA element modulatory factor 1 DNA binding DUF869 PF05911.6 CEH13141.1 - 0.0019 16.5 28.0 0.0019 16.5 19.4 2.1 1 1 1 2 2 2 1 Plant protein of unknown function (DUF869) ATG16 PF08614.6 CEH13141.1 - 0.049 13.4 54.3 0.16 11.7 10.0 3.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 CEH13141.1 - 0.28 10.3 15.8 0.31 10.1 1.1 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CEH13141.1 - 1.7 7.0 49.3 1.4 7.3 16.4 2.3 1 1 1 2 2 2 0 AAA domain DUF3450 PF11932.3 CEH13141.1 - 4.3 6.5 31.8 3.3 6.9 8.3 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) CALCOCO1 PF07888.6 CEH13141.1 - 4.7 5.3 51.2 0.51 8.5 9.3 2.6 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.4 CEH13141.1 - 5.2 5.9 51.2 1.3 7.8 12.0 3.0 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 GAS PF13851.1 CEH13141.1 - 9.3 5.3 60.7 1.2 8.3 13.2 4.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF3053 PF11254.3 CEH13143.1 - 0.019 14.2 0.1 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) UPF0121 PF03661.8 CEH13143.1 - 0.13 11.3 0.1 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) TP53IP5 PF15331.1 CEH13143.1 - 0.95 9.3 6.9 0.074 12.9 0.2 1.9 1 1 1 2 2 2 0 Cellular tumour antigen p53-inducible 5 DUF3552 PF12072.3 CEH13144.1 - 0.011 15.0 4.7 0.013 14.7 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) vATP-synt_E PF01991.13 CEH13144.1 - 0.12 11.6 2.4 0.13 11.4 1.7 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit I_LWEQ PF01608.12 CEH13144.1 - 0.15 11.9 0.8 0.17 11.7 0.6 1.1 1 0 0 1 1 1 0 I/LWEQ domain OEP PF02321.13 CEH13144.1 - 0.19 11.3 1.5 0.21 11.1 1.0 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein DUF536 PF04394.9 CEH13144.1 - 1.2 8.9 11.3 5.2 6.8 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function, DUF536 WD40 PF00400.27 CEH13145.1 - 4.1e-54 178.6 10.4 1.1e-09 37.7 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 CEH13145.1 - 2e-09 36.5 2.4 4.6e-09 35.3 1.7 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like HsbA PF12296.3 CEH13146.1 - 0.00015 21.5 0.6 0.00024 20.9 0.4 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF2265 PF10023.4 CEH13148.1 - 0.1 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Zn_clus PF00172.13 CEH13149.1 - 0.0014 18.5 5.8 0.0014 18.5 4.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 CEH13150.1 - 6.6e-08 32.7 0.0 4.2e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding LIP PF03583.9 CEH13152.1 - 8.7e-53 179.3 0.6 1.2e-52 178.8 0.4 1.2 1 0 0 1 1 1 1 Secretory lipase DUF829 PF05705.9 CEH13152.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) HsbA PF12296.3 CEH13153.1 - 1.3e-06 28.3 0.3 1.7e-06 27.8 0.2 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.7 CEH13153.1 - 0.055 13.2 0.5 0.084 12.6 0.4 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SecD_SecF PF02355.11 CEH13153.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein export membrane protein HsbA PF12296.3 CEH13154.1 - 1.1e-09 38.1 0.1 1.8e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF4449 PF14613.1 CEH13156.1 - 1e-16 61.2 14.4 1.5e-16 60.7 1.2 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) Gluconate_2-dh3 PF13618.1 CEH13156.1 - 0.25 11.4 9.5 1.1 9.4 5.3 2.7 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF1910 PF08928.5 CEH13156.1 - 0.34 10.9 3.0 0.68 9.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) RBM39linker PF15519.1 CEH13159.1 - 6.7 7.0 7.1 0.77 10.0 1.2 2.2 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Sec7 PF01369.15 CEH13160.1 - 2.3e-27 95.8 0.0 3.8e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain SAM_1 PF00536.25 CEH13160.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CEH13160.1 - 5.7e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 CEH13160.1 - 0.045 13.9 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 PH domain ALIX_LYPXL_bnd PF13949.1 CEH13160.1 - 0.22 10.4 1.8 0.41 9.5 1.3 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Iso_dh PF00180.15 CEH13161.1 - 1.9e-79 267.1 0.0 2.4e-79 266.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase His_biosynth PF00977.16 CEH13163.1 - 2e-19 69.7 0.0 7.4e-10 38.4 0.0 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 CEH13163.1 - 0.047 12.8 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Pectinesterase PF01095.14 CEH13164.1 - 3.9e-11 42.0 0.7 7.1e-11 41.2 0.5 1.5 1 1 0 1 1 1 1 Pectinesterase RRM_1 PF00076.17 CEH13165.1 - 3.2e-25 87.5 0.0 3.2e-13 49.0 0.0 4.9 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH13165.1 - 5.5e-13 48.6 0.0 0.00067 19.5 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH13165.1 - 1e-10 41.2 0.0 0.015 15.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMT PF02366.13 CEH13167.1 - 1.3e-75 253.9 16.2 2.6e-75 252.9 11.3 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CEH13167.1 - 8.7e-17 61.2 4.4 3.1e-15 56.2 1.5 2.2 1 1 1 2 2 2 2 MIR domain LIP PF03583.9 CEH13168.1 - 1.9e-58 197.9 0.1 2.8e-58 197.4 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 CEH13168.1 - 5.7e-08 32.6 0.7 2.3e-07 30.6 0.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH13168.1 - 3.4e-05 23.8 0.1 9.7e-05 22.3 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAE PF03283.8 CEH13168.1 - 0.012 14.2 0.1 0.021 13.4 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase ABC_tran PF00005.22 CEH13169.1 - 5.7e-24 84.9 0.0 1.7e-23 83.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CEH13169.1 - 8.3e-12 45.6 0.3 9.7e-05 22.4 0.1 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CEH13169.1 - 1.4e-06 27.7 0.2 0.0063 15.7 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 CEH13169.1 - 0.00025 20.8 0.2 0.00025 20.8 0.1 2.1 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 CEH13169.1 - 0.00076 18.9 0.0 0.0033 16.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CEH13169.1 - 0.0011 18.1 0.0 0.022 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CEH13169.1 - 0.0012 19.6 0.0 0.0061 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 CEH13169.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 CEH13169.1 - 0.0089 15.5 0.7 0.068 12.6 0.3 2.0 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 CEH13169.1 - 0.009 15.6 0.2 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.1 CEH13169.1 - 0.011 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CEH13169.1 - 0.011 15.8 0.0 0.19 11.8 0.0 2.4 3 0 0 3 3 2 0 RNA helicase Miro PF08477.8 CEH13169.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 CEH13169.1 - 0.016 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 CEH13169.1 - 0.016 14.4 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 CEH13169.1 - 0.027 14.3 0.2 0.15 12.0 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 CEH13169.1 - 0.042 12.6 0.0 0.093 11.4 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 CEH13169.1 - 0.055 13.7 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CEH13169.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CEH13169.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CEH13169.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Dynamin family GTP_EFTU PF00009.22 CEH13169.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CEH13169.1 - 0.13 12.3 0.1 0.47 10.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain Thymidylat_synt PF00303.14 CEH13170.1 - 6.3e-94 313.9 0.0 7e-94 313.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 CEH13171.1 - 2.9e-24 85.9 0.0 3.4e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cache_2 PF08269.6 CEH13171.1 - 0.0096 15.8 0.1 5.5 7.0 0.0 2.4 2 0 0 2 2 2 2 Cache domain DUF4470 PF14737.1 CEH13173.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4470) RVT_1 PF00078.22 CEH13174.1 - 0.0078 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CEH13175.1 - 0.19 12.0 1.8 0.46 10.8 1.3 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.2 CEH13175.1 - 0.33 10.7 3.6 0.16 11.7 0.3 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HMG_CoA_synt_N PF01154.12 CEH13176.1 - 6.7e-86 286.2 0.2 1.3e-85 285.3 0.0 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 CEH13176.1 - 3.7e-82 276.0 0.2 1.2e-81 274.3 0.1 1.7 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.5 CEH13176.1 - 0.0098 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 CEH13176.1 - 0.041 13.5 0.2 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SLAC1 PF03595.12 CEH13177.1 - 1.6e-85 286.6 47.4 1.9e-85 286.4 32.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel FF PF01846.14 CEH13178.1 - 8.1e-13 48.1 0.0 9.1e-09 35.1 0.0 3.7 3 0 0 3 3 3 2 FF domain WW PF00397.21 CEH13178.1 - 4.7e-08 32.7 13.2 0.00023 20.9 3.3 2.9 2 0 0 2 2 2 2 WW domain RRM_1 PF00076.17 CEH13178.1 - 1.3e-05 24.7 0.0 0.007 15.9 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH13178.1 - 0.047 13.6 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rsc14 PF08586.5 CEH13178.1 - 0.29 11.6 2.0 1.7 9.1 0.1 3.3 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Thioredoxin PF00085.15 CEH13179.1 - 2.2e-28 97.9 0.0 3.1e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CEH13179.1 - 4.3e-10 39.7 0.3 1.2e-09 38.3 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEH13179.1 - 1.6e-06 28.1 0.0 4.4e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CEH13179.1 - 2.2e-05 24.3 0.0 4.7e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CEH13179.1 - 0.00087 18.8 0.0 0.00095 18.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 CEH13179.1 - 0.0017 18.1 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.19 CEH13179.1 - 0.0058 16.5 0.1 0.019 14.9 0.0 1.9 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin_3 PF13192.1 CEH13179.1 - 0.0059 16.3 0.0 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin domain AhpC-TSA PF00578.16 CEH13179.1 - 0.039 13.6 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_4 PF13462.1 CEH13179.1 - 0.099 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Apis_Csd PF11671.3 CEH13180.1 - 5.1 6.8 5.5 12 5.6 3.8 1.6 1 0 0 1 1 1 0 Complementary sex determiner protein Kelch_4 PF13418.1 CEH13181.1 - 6.2e-40 134.7 14.7 4.6e-08 32.7 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CEH13181.1 - 3.4e-38 128.9 10.6 2.4e-09 37.0 0.0 7.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 CEH13181.1 - 1.1e-30 104.9 4.4 7.2e-05 22.2 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CEH13181.1 - 1.9e-27 94.7 9.4 1.3e-06 28.2 0.1 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 CEH13181.1 - 3.7e-24 83.8 10.7 4e-05 23.5 0.0 6.4 4 2 2 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CEH13181.1 - 3e-22 77.4 11.6 4.6e-07 29.3 0.1 6.3 6 0 0 6 6 6 5 Kelch motif PQQ_3 PF13570.1 CEH13181.1 - 0.0053 16.9 3.3 5.1 7.5 0.0 5.2 3 1 2 5 5 5 1 PQQ-like domain Daxx PF03344.10 CEH13181.1 - 8.3 4.7 11.4 15 3.8 7.9 1.5 1 0 0 1 1 1 0 Daxx Family MFS_1 PF07690.11 CEH13182.1 - 9.2e-34 116.6 30.8 9.2e-34 116.6 21.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH13182.1 - 6.6e-11 41.4 13.5 2.1e-10 39.7 9.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 CEH13182.1 - 1.4e-06 26.8 2.0 2e-06 26.3 1.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rick_17kDa_Anti PF05433.10 CEH13182.1 - 4.7 6.9 7.1 0.21 11.2 0.6 2.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain Zn_clus PF00172.13 CEH13183.1 - 0.0068 16.2 7.7 0.014 15.3 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.14 CEH13185.1 - 7.2e-22 77.7 0.1 2.1e-21 76.3 0.0 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family MFS_1 PF07690.11 CEH13188.1 - 2.5e-16 59.3 30.1 3.1e-12 45.9 17.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 CEH13188.1 - 6.1e-13 48.5 4.9 6.1e-13 48.5 3.4 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF3482 PF11981.3 CEH13188.1 - 0.075 12.2 0.3 0.17 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Phage_holin_1 PF04531.8 CEH13188.1 - 0.52 10.4 2.1 16 5.6 0.1 3.0 2 0 0 2 2 2 0 Bacteriophage holin TAF PF02969.12 CEH13189.1 - 8.2e-17 60.9 0.0 2.4e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 CEH13189.1 - 2.2e-10 40.5 0.1 6.4e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 CEH13189.1 - 1.1e-05 25.4 0.0 2.8e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 LEAP-2 PF07359.6 CEH13190.1 - 0.0051 16.4 0.6 0.02 14.5 0.4 2.0 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) DUF4229 PF14012.1 CEH13190.1 - 0.033 14.0 0.3 0.075 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) PAPA-1 PF04795.7 CEH13190.1 - 0.045 14.4 0.4 0.09 13.4 0.3 1.4 1 0 0 1 1 1 0 PAPA-1-like conserved region AAA_33 PF13671.1 CEH13190.1 - 0.1 12.4 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain EB PF01683.13 CEH13190.1 - 0.31 11.1 24.5 0.35 10.9 4.0 3.6 2 1 2 4 4 4 0 EB module WD40 PF00400.27 CEH13191.1 - 2.8e-26 90.3 9.7 3.5e-06 26.6 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CEH13191.1 - 2.2e-06 27.5 0.4 0.0046 16.6 0.0 2.9 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A NUDIX_4 PF14815.1 CEH13192.1 - 3.8e-19 68.2 0.8 1.1e-17 63.4 0.5 2.7 2 1 0 2 2 2 1 NUDIX domain HhH-GPD PF00730.20 CEH13192.1 - 3.3e-15 56.2 0.0 8.4e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CEH13192.1 - 4.6e-06 26.0 0.0 1.9e-05 24.1 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 CEH13192.1 - 0.16 12.2 10.6 0.43 10.8 7.4 1.8 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III DDE_Tnp_1_6 PF13751.1 CEH13192.1 - 0.45 10.5 5.9 0.75 9.8 0.2 3.4 3 0 0 3 3 3 0 Transposase DDE domain HHV6-IE PF03753.8 CEH13194.1 - 1.6 6.1 1.9 2.6 5.3 1.3 1.2 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein zf-C2H2_jaz PF12171.3 CEH13196.1 - 6e-08 32.5 1.1 1.2e-07 31.6 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEH13196.1 - 0.004 17.3 0.4 0.007 16.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CEH13196.1 - 0.0069 16.4 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Ribosomal_L35Ae PF01247.13 CEH13197.1 - 1.9e-42 142.9 2.0 2.1e-42 142.7 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CEH13197.1 - 0.00037 20.3 0.1 0.73 9.8 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain MFS_1 PF07690.11 CEH13201.1 - 4.3e-32 111.2 30.0 4.3e-32 111.2 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH13201.1 - 4.2e-05 22.3 18.0 0.00083 18.0 12.5 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter Amidinotransf PF02274.12 CEH13203.1 - 9.9e-12 44.5 0.0 1.1e-11 44.3 0.0 1.3 1 1 0 1 1 1 1 Amidinotransferase Fungal_trans PF04082.13 CEH13205.1 - 4.4e-09 35.5 0.0 0.00015 20.7 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH13205.1 - 7.7e-05 22.5 9.1 0.00014 21.7 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSX_dimer PF08828.5 CEH13205.1 - 0.26 10.8 0.6 2.9 7.5 0.2 2.3 2 0 0 2 2 2 0 Doublesex dimerisation domain His_Phos_1 PF00300.17 CEH13206.1 - 9.6e-41 139.5 0.0 1.1e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GTPase_Cys_C PF12631.2 CEH13206.1 - 0.078 13.3 0.1 2.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMtag PF10159.4 CEH13207.1 - 5.6e-28 96.8 7.2 5.6e-28 96.8 5.0 3.1 2 1 0 2 2 2 1 Kinase phosphorylation protein LSM PF01423.17 CEH13207.1 - 8.3e-06 25.2 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 LSM domain CsbD PF05532.7 CEH13213.1 - 0.00013 21.5 0.6 0.0003 20.4 0.4 1.6 1 0 0 1 1 1 1 CsbD-like Ubiq_cyt_C_chap PF03981.7 CEH13214.1 - 9.9e-28 96.7 0.0 5.1e-25 87.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone HSP70 PF00012.15 CEH13215.1 - 1.4e-67 228.0 0.6 1.4e-67 228.0 0.4 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CEH13215.1 - 1.1e-06 27.5 2.7 1.9e-05 23.4 0.4 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin PF00022.14 CEH13215.1 - 2.2e-06 26.3 0.5 0.0027 16.1 0.1 2.2 1 1 0 2 2 2 2 Actin PilM_2 PF11104.3 CEH13215.1 - 3.4e-05 22.9 0.0 0.00016 20.6 0.0 2.0 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; FtsA PF14450.1 CEH13215.1 - 0.012 15.3 1.8 2.1 8.1 0.1 3.4 4 1 0 4 4 4 0 Cell division protein FtsA Alpha_L_fucos PF01120.12 CEH13215.1 - 0.045 12.6 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-fucosidase eIF-3c_N PF05470.7 CEH13216.1 - 3.8e-138 461.2 3.8 4.4e-138 460.9 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CEH13216.1 - 3.5e-14 52.9 0.0 2e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 PCI domain eIF-3c_N PF05470.7 CEH13217.1 - 7e-19 67.3 3.0 8e-19 67.1 2.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus VirJ PF06057.6 CEH13217.1 - 0.011 15.5 0.3 0.012 15.3 0.2 1.0 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) AAA PF00004.24 CEH13218.1 - 9.3e-41 139.1 0.0 1.9e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEH13218.1 - 8.6e-05 22.5 0.1 0.0092 15.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CEH13218.1 - 0.00024 20.8 0.1 0.0024 17.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CEH13218.1 - 0.00031 20.8 0.5 0.015 15.4 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CEH13218.1 - 0.00038 20.4 0.1 0.0041 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CEH13218.1 - 0.00086 18.4 0.0 0.0018 17.3 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 CEH13218.1 - 0.0016 17.6 0.1 0.027 13.6 0.0 2.6 3 0 0 3 3 3 1 PhoH-like protein AAA_17 PF13207.1 CEH13218.1 - 0.0016 19.2 0.0 0.0054 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH13218.1 - 0.0099 15.6 0.1 0.027 14.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CEH13218.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CEH13218.1 - 0.013 14.8 2.0 0.15 11.4 0.1 2.6 2 1 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 CEH13218.1 - 0.014 14.5 0.3 0.043 12.9 0.0 1.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CEH13218.1 - 0.019 14.3 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 CEH13218.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 CEH13218.1 - 0.023 13.6 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 CEH13218.1 - 0.067 12.7 0.1 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_L4 PF00573.17 CEH13220.1 - 2.9e-43 147.4 0.6 2.9e-43 147.4 0.4 2.0 2 1 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CEH13220.1 - 9.3e-23 79.9 6.2 9.3e-23 79.9 4.3 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PSRT PF07636.6 CEH13221.1 - 0.045 13.2 1.6 3.4 7.2 0.1 2.5 2 0 0 2 2 2 0 PSRT SAP PF02037.22 CEH13222.1 - 5.7e-05 22.5 0.3 5.7e-05 22.5 0.2 1.9 2 0 0 2 2 2 1 SAP domain DEAD PF00270.24 CEH13223.1 - 6e-35 120.2 0.0 5.3e-33 113.8 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CEH13223.1 - 3.1e-22 77.8 0.1 7e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CEH13223.1 - 3.1e-18 65.4 0.0 9.1e-18 63.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH13223.1 - 0.0011 18.8 2.6 0.0029 17.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CEH13223.1 - 0.062 12.3 0.0 0.062 12.3 0.0 2.9 3 1 1 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit SecA_DEAD PF07517.9 CEH13223.1 - 0.068 12.4 0.0 0.068 12.4 0.0 2.0 2 0 0 2 2 2 0 SecA DEAD-like domain Phos_pyr_kin PF08543.7 CEH13224.1 - 2.9e-73 246.0 0.9 2.3e-51 174.4 0.0 3.2 2 1 1 3 3 3 3 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CEH13224.1 - 5.9e-30 104.6 0.1 8.6e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Dynamin_M PF01031.15 CEH13225.1 - 1.9e-111 371.5 0.0 3e-111 370.9 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CEH13225.1 - 5.4e-55 185.7 0.0 9.8e-55 184.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CEH13225.1 - 2.7e-27 94.4 1.2 7.8e-27 93.0 0.8 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CEH13225.1 - 0.0024 17.7 0.0 0.028 14.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CEH13225.1 - 0.035 14.5 0.0 0.08 13.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein TipAS PF07739.8 CEH13225.1 - 0.18 12.1 0.0 0.63 10.3 0.0 1.9 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain RabGAP-TBC PF00566.13 CEH13226.1 - 1e-48 165.6 0.1 1.5e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 CEH13226.1 - 8.4e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.1 CEH13226.1 - 0.0037 17.3 0.3 0.28 11.3 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CEH13226.1 - 0.0059 16.1 0.1 0.35 10.5 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CEH13226.1 - 0.014 15.2 0.3 1.5 8.9 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain PQ-loop PF04193.9 CEH13228.1 - 2.6e-17 62.1 1.4 1.2e-12 47.1 0.2 2.7 2 0 0 2 2 2 2 PQ loop repeat DoxX_2 PF13564.1 CEH13228.1 - 0.014 15.3 3.1 0.035 14.0 0.4 2.4 2 0 0 2 2 2 0 DoxX-like family DUF641 PF04859.7 CEH13230.1 - 0.024 14.4 0.6 0.059 13.1 0.4 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF3405 PF11885.3 CEH13231.1 - 1.4e-139 465.5 0.2 6.3e-83 278.6 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) Wzz PF02706.10 CEH13231.1 - 0.41 10.4 0.7 0.7 9.6 0.5 1.3 1 0 0 1 1 1 0 Chain length determinant protein Herpes_capsid PF06112.6 CEH13231.1 - 6 6.8 11.1 0.035 14.1 1.6 1.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein WD40 PF00400.27 CEH13233.1 - 3.2e-40 134.6 18.9 7.2e-07 28.8 0.3 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat VCBS PF13517.1 CEH13233.1 - 0.033 14.5 0.1 0.34 11.2 0.1 2.6 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DNA_binding_1 PF01035.15 CEH13234.1 - 2e-21 75.5 0.0 8.1e-21 73.5 0.0 1.9 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Periviscerokin PF08259.6 CEH13234.1 - 2.7 8.3 5.4 3.2 8.1 0.7 2.6 2 0 0 2 2 2 0 Periviscerokinin family Mg_trans_NIPA PF05653.9 CEH13235.1 - 7.1e-92 307.5 22.8 9.7e-92 307.1 15.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CEH13235.1 - 1.7e-05 24.8 8.8 1.7e-05 24.8 6.1 3.6 2 2 1 4 4 4 1 EamA-like transporter family EmrE PF13536.1 CEH13235.1 - 3.6e-05 23.9 9.1 3.6e-05 23.9 6.3 3.4 1 1 1 3 3 3 1 Multidrug resistance efflux transporter SKN1 PF03935.10 CEH13236.1 - 5.4e-171 569.1 5.1 9e-170 565.1 3.5 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 CEH13236.1 - 9.2e-06 25.0 0.1 0.024 13.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Dabb PF07876.7 CEH13237.1 - 2.2e-16 60.0 0.2 2.5e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Glutaredoxin PF00462.19 CEH13239.1 - 1.9e-14 53.3 0.0 3.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 CEH13239.1 - 0.0003 20.9 0.0 0.00092 19.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain DSBA PF01323.15 CEH13239.1 - 0.14 11.6 0.0 18 4.8 0.0 2.2 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Pap_E4 PF02711.9 CEH13240.1 - 1.1 10.1 6.5 1.3 9.8 4.5 1.2 1 0 0 1 1 1 0 E4 protein Dfp1_Him1_M PF08630.5 CEH13241.1 - 1e-27 96.3 0.0 2.1e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 CEH13241.1 - 2.7e-20 71.7 0.3 6.5e-20 70.5 0.2 1.7 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 CEH13241.1 - 0.0082 15.9 0.0 0.031 14.1 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain NUDIX PF00293.23 CEH13242.1 - 2e-16 59.8 0.3 2.3e-16 59.6 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 CEH13242.1 - 0.00021 20.6 0.3 0.00084 18.7 0.2 1.9 1 1 0 1 1 1 1 NUDIX domain Suc_Fer-like PF06999.7 CEH13243.1 - 8.1e-23 81.6 0.0 2.6e-22 79.9 0.0 1.7 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.22 CEH13243.1 - 3.7e-09 36.1 2.2 1.8e-08 33.9 1.5 2.1 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Zn_clus PF00172.13 CEH13244.1 - 0.0014 18.5 8.1 0.0043 16.9 5.6 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_ab PF00006.20 CEH13245.1 - 1.3e-59 201.3 0.0 1.8e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEH13245.1 - 1.6e-16 60.7 0.2 3.3e-16 59.7 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEH13245.1 - 6.1e-11 42.3 0.9 9.7e-11 41.7 0.1 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CEH13245.1 - 0.00097 18.9 0.1 0.0021 17.9 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain TPR_20 PF14561.1 CEH13246.1 - 0.0013 18.7 0.2 1.2 9.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.9 CEH13246.1 - 0.066 12.4 0.3 3.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Coatomer epsilon subunit Mito_carr PF00153.22 CEH13247.1 - 1e-61 204.6 4.7 2.1e-20 72.2 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2361 PF10153.4 CEH13248.1 - 1.8e-24 86.0 5.0 1.8e-24 86.0 3.4 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DUF3435 PF11917.3 CEH13248.1 - 0.0061 15.3 4.9 0.0098 14.6 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Exonuc_VII_L PF02601.10 CEH13248.1 - 0.026 13.7 0.8 0.036 13.2 0.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.7 CEH13248.1 - 0.095 11.1 2.8 0.11 10.9 1.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cytochrom_B562 PF07361.6 CEH13248.1 - 0.67 10.4 7.9 2 8.8 0.9 2.6 2 1 1 3 3 3 0 Cytochrome b562 Orbi_VP6 PF01516.11 CEH13248.1 - 2.5 7.0 9.1 5.6 5.9 6.3 1.5 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF2058 PF09831.4 CEH13248.1 - 3 7.6 7.4 6 6.7 5.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) CCDC-167 PF15188.1 CEH13248.1 - 3.3 7.7 8.2 0.13 12.1 1.3 1.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DEAD PF00270.24 CEH13249.1 - 3.6e-39 133.9 0.1 5.7e-39 133.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH13249.1 - 1.2e-22 79.5 0.5 9.4e-12 44.6 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CEH13249.1 - 2.7e-05 24.0 0.0 5.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FLO_LFY PF01698.11 CEH13249.1 - 0.0064 15.3 0.4 0.012 14.4 0.3 1.4 1 0 0 1 1 1 1 Floricaula / Leafy protein zf-CCHC PF00098.18 CEH13252.1 - 3.2e-05 23.6 2.1 3.7e-05 23.4 0.3 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.1 CEH13252.1 - 0.0026 17.2 0.1 0.0065 15.9 0.1 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.12 CEH13252.1 - 0.0086 16.1 0.2 0.099 12.7 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 CEH13252.1 - 0.092 12.5 0.3 0.2 11.3 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CEH13252.1 - 0.1 12.2 0.4 0.19 11.3 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Choline_transpo PF04515.7 CEH13253.1 - 3.8e-65 219.8 16.4 4.3e-65 219.6 11.3 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF4013 PF13197.1 CEH13253.1 - 0.62 9.3 15.8 0.5 9.6 5.2 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF4013) GMC_oxred_C PF05199.8 CEH13254.1 - 2.7e-18 66.6 0.1 5.5e-18 65.6 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CEH13254.1 - 1.2e-16 60.6 0.0 1.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DUF3140 PF11338.3 CEH13254.1 - 0.1 12.7 0.0 0.54 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) PIG-L PF02585.12 CEH13256.1 - 1.3e-26 93.5 0.0 1.9e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Lipase_3 PF01764.20 CEH13257.1 - 0.038 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 CEH13257.1 - 0.047 13.5 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Bestrophin PF01062.16 CEH13258.1 - 5.3e-31 107.6 0.0 7.8e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Clat_adaptor_s PF01217.15 CEH13259.1 - 8.9e-11 41.6 0.0 1.3e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Mon1 PF03164.9 CEH13260.1 - 1.2e-75 254.7 0.0 1.1e-72 244.9 0.0 2.2 2 0 0 2 2 2 2 Trafficking protein Mon1 RF-1 PF00472.15 CEH13261.1 - 5.5e-21 74.5 2.5 5.5e-21 74.5 1.8 2.8 3 0 0 3 3 3 1 RF-1 domain Glyco_hydro_16 PF00722.16 CEH13262.1 - 1.8e-09 37.1 0.0 2.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF4136 PF13590.1 CEH13262.1 - 0.065 13.2 0.1 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) DLH PF01738.13 CEH13263.1 - 4.1e-24 85.0 1.5 4.9e-24 84.8 1.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CEH13263.1 - 4.3e-13 49.2 0.3 5.8e-13 48.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH13263.1 - 1.2e-08 35.1 0.3 0.0004 20.3 0.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH13263.1 - 0.0044 16.6 0.0 2.9 7.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF1183 PF06682.7 CEH13264.1 - 2e-53 182.1 0.1 2.5e-53 181.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) adh_short PF00106.20 CEH13265.1 - 3.4e-20 72.6 0.3 4.3e-20 72.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH13265.1 - 1.7e-06 28.0 0.0 2.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH13265.1 - 0.00016 21.4 0.3 0.00022 20.9 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CEH13265.1 - 0.007 15.5 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) CDO_I PF05995.7 CEH13265.1 - 0.024 13.8 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I NAD_binding_8 PF13450.1 CEH13265.1 - 0.062 13.3 2.3 1.4 8.9 0.7 3.3 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain AAA_19 PF13245.1 CEH13265.1 - 0.12 12.1 0.3 14 5.5 0.1 3.4 3 0 0 3 3 3 0 Part of AAA domain zf-SNAP50_C PF12251.3 CEH13266.1 - 4.3e-07 29.5 1.6 3e-06 26.7 0.1 2.8 2 1 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal NRDE PF05742.7 CEH13267.1 - 1.7e-33 116.1 0.0 3.7e-20 72.3 0.0 4.1 2 1 0 2 2 2 2 NRDE protein MIP PF00230.15 CEH13268.1 - 8.7e-42 143.1 14.6 1.2e-41 142.6 10.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Mito_fiss_reg PF05308.6 CEH13268.1 - 0.098 12.0 9.4 0.2 10.9 6.5 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator MFS_1 PF07690.11 CEH13269.1 - 1.4e-22 79.9 37.0 2.2e-15 56.2 11.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH13269.1 - 3.7e-18 65.3 17.8 1e-17 63.8 12.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Oxidored_q3 PF00499.15 CEH13269.1 - 0.013 15.2 0.0 0.013 15.2 0.0 2.8 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2583 PF10762.4 CEH13269.1 - 0.023 14.8 0.5 0.088 12.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) MFS_1 PF07690.11 CEH13272.1 - 7.9e-38 130.0 44.2 1.1e-37 129.6 30.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF834 PF05754.9 CEH13272.1 - 0.0069 16.1 0.2 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF834) DUF2530 PF10745.4 CEH13272.1 - 0.14 12.1 5.8 3.6 7.6 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) RAI1 PF08652.6 CEH13273.1 - 1e-17 63.6 0.0 2.1e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Acyl-CoA_dh_1 PF00441.19 CEH13274.1 - 3.9e-42 143.8 1.3 3.9e-42 143.8 0.9 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CEH13274.1 - 6.3e-36 123.3 0.0 1.5e-35 122.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CEH13274.1 - 9.6e-18 63.4 0.0 2.1e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CEH13274.1 - 6.8e-16 58.7 0.8 6.8e-16 58.7 0.5 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CEH13274.1 - 0.0073 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal HpaB_N PF11794.3 CEH13274.1 - 0.15 11.4 0.1 0.67 9.2 0.0 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Glyco_hydro_31 PF01055.21 CEH13275.1 - 1.2e-96 324.2 1.2 2e-96 323.5 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CEH13275.1 - 3.2e-07 30.0 0.3 9.9e-07 28.5 0.2 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Aldose_epim PF01263.15 CEH13276.1 - 9.8e-57 192.3 0.0 1.2e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase PADR1 PF08063.7 CEH13276.1 - 0.26 10.6 1.3 0.49 9.8 0.4 1.8 2 0 0 2 2 2 0 PADR1 (NUC008) domain Het-C PF07217.6 CEH13277.1 - 7.3e-215 714.7 0.0 2.1e-214 713.2 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Epimerase PF01370.16 CEH13278.1 - 5.1e-14 52.2 0.0 1.6e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CEH13278.1 - 4.3e-10 38.7 0.0 1.1e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CEH13278.1 - 3.8e-07 29.2 0.0 6.4e-06 25.2 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 CEH13278.1 - 9.6e-07 28.9 0.4 7.9e-06 26.0 0.3 2.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CEH13278.1 - 0.00067 18.9 0.7 0.0016 17.7 0.0 2.0 3 1 0 3 3 3 1 NmrA-like family adh_short PF00106.20 CEH13278.1 - 0.02 14.8 1.4 0.98 9.3 1.0 2.3 1 1 0 1 1 1 0 short chain dehydrogenase DUF3425 PF11905.3 CEH13279.1 - 1.3e-17 63.9 0.8 2e-17 63.3 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 CEH13279.1 - 0.14 12.1 7.0 0.068 13.1 2.0 2.2 2 0 0 2 2 2 0 bZIP transcription factor DUF2017 PF09438.5 CEH13283.1 - 0.019 14.5 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) Synaptobrevin PF00957.16 CEH13285.1 - 2.5e-25 87.9 1.1 3.2e-25 87.5 0.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CEH13285.1 - 4.4e-21 74.2 0.0 7.7e-21 73.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Hypoth_Ymh PF09509.5 CEH13287.1 - 0.081 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) p450 PF00067.17 CEH13288.1 - 4.5e-77 259.5 0.0 3.7e-49 167.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MBOAT PF03062.14 CEH13289.1 - 2.1e-48 165.1 0.0 7.9e-48 163.2 0.0 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family CD24 PF14984.1 CEH13289.1 - 0.23 11.2 0.1 0.23 11.2 0.1 3.4 2 1 1 3 3 3 0 CD24 protein PITH PF06201.8 CEH13290.1 - 6.6e-31 107.1 0.0 1.7e-30 105.8 0.0 1.7 2 1 0 2 2 2 1 PITH domain DUF4031 PF13223.1 CEH13290.1 - 0.023 14.8 0.0 9.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4031) Nop PF01798.13 CEH13291.1 - 1.3e-58 196.5 0.1 2.7e-58 195.5 0.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CEH13291.1 - 9.7e-25 86.1 0.1 2e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain DUF2431 PF10354.4 CEH13291.1 - 1.5e-20 73.8 0.1 4.3e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) UCH PF00443.24 CEH13292.1 - 1.3e-46 158.8 0.0 3.4e-46 157.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CEH13292.1 - 1.9e-25 88.7 11.8 8.9e-21 73.7 0.6 2.7 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CEH13292.1 - 4.5e-17 62.4 0.0 3.8e-07 29.8 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 CEH13292.1 - 1.3e-07 31.2 1.0 5.3e-07 29.2 0.1 2.4 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CEH13292.1 - 0.024 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Ribosomal_L33 PF00471.15 CEH13292.1 - 0.52 10.6 1.9 8.6 6.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L33 MitMem_reg PF13012.1 CEH13293.1 - 6.2e-30 103.6 0.5 1.2e-29 102.6 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CEH13293.1 - 7.4e-25 86.9 0.0 1.7e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Nucleoside_tran PF01733.13 CEH13294.1 - 5.8e-29 101.2 7.0 2.2e-16 59.9 0.0 3.4 2 1 1 3 3 3 2 Nucleoside transporter ATP_bind_1 PF03029.12 CEH13295.1 - 1.4e-73 247.3 0.0 2.9e-73 246.3 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 CEH13295.1 - 0.00019 21.3 0.0 0.00046 20.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 CEH13295.1 - 0.0012 19.6 0.0 0.0039 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CEH13295.1 - 0.0041 16.6 0.3 0.0081 15.6 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.15 CEH13295.1 - 0.0069 15.1 0.2 0.52 8.9 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit CbiA PF01656.18 CEH13295.1 - 0.0086 15.4 0.3 0.1 12.0 0.1 2.4 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 CEH13295.1 - 0.018 15.3 1.0 0.032 14.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CEH13295.1 - 0.03 14.1 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CEH13295.1 - 0.034 13.4 0.0 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.1 CEH13295.1 - 0.044 14.1 0.0 0.52 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CEH13295.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 CEH13295.1 - 0.064 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CEH13295.1 - 0.074 13.3 0.0 0.17 12.1 0.0 1.7 2 0 0 2 2 1 0 ABC transporter AAA_16 PF13191.1 CEH13295.1 - 0.076 12.9 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Syntaxin PF00804.20 CEH13295.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Syntaxin Asp_protease PF09668.5 CEH13296.1 - 6.1e-60 200.2 0.0 9.2e-60 199.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 CEH13296.1 - 1.5e-10 41.4 0.1 8.1e-10 39.0 0.0 2.4 3 0 0 3 3 3 1 Aspartyl protease ubiquitin PF00240.18 CEH13296.1 - 1e-08 34.4 0.0 2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.6 CEH13296.1 - 1.7e-07 31.2 0.0 3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CEH13296.1 - 6e-07 29.1 0.0 2.5e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 CEH13296.1 - 2.1e-05 24.2 0.1 4.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.15 CEH13296.1 - 8.4e-05 22.4 0.2 0.00042 20.1 0.0 2.3 3 0 0 3 3 3 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 CEH13296.1 - 0.0015 18.1 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 CEH13296.1 - 0.0078 15.7 0.3 0.023 14.2 0.2 1.8 1 0 0 1 1 1 1 UBA-like domain SpoIIAA-like PF11964.3 CEH13296.1 - 0.061 13.6 0.2 0.66 10.2 0.0 2.5 2 1 0 2 2 2 0 SpoIIAA-like Asp-B-Hydro_N PF05279.6 CEH13296.1 - 0.074 12.8 5.8 0.12 12.2 4.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MF_alpha_N PF05436.6 CEH13296.1 - 0.11 12.1 0.4 0.27 10.9 0.3 1.6 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Condensation PF00668.15 CEH13297.1 - 0.0025 16.7 0.1 0.0093 14.8 0.0 2.0 2 0 0 2 2 2 1 Condensation domain MFS_1 PF07690.11 CEH13298.1 - 9.1e-42 143.0 26.2 9.1e-42 143.0 18.1 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH13298.1 - 3.4e-12 45.6 24.1 5.3e-11 41.7 16.7 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 CEH13298.1 - 9.4e-05 20.7 5.4 0.00018 19.7 3.7 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 CEH13298.1 - 0.17 9.8 5.4 4.4 5.2 2.7 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S8 PF00082.17 CEH13300.1 - 1.7e-46 158.6 0.0 3.1e-46 157.7 0.0 1.5 1 1 0 1 1 1 1 Subtilase family TPPII PF12580.3 CEH13300.1 - 4.3e-45 153.4 0.0 7.3e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II tRNA-synt_2b PF00587.20 CEH13301.1 - 1.8e-30 105.7 0.0 2.8e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEH13301.1 - 1.8e-05 24.5 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Abhydrolase_6 PF12697.2 CEH13302.1 - 0.017 14.9 0.2 0.054 13.3 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH13302.1 - 0.025 14.3 0.1 0.042 13.6 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1749 PF08538.5 CEH13302.1 - 0.031 13.1 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.20 CEH13302.1 - 0.042 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) WD40 PF00400.27 CEH13303.1 - 9.1e-52 171.1 23.6 4.1e-10 39.1 0.0 9.0 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 CEH13303.1 - 2.3e-11 42.5 5.2 0.0052 14.9 0.1 5.9 3 1 2 6 6 6 5 Nucleoporin Nup120/160 F-box-like PF12937.2 CEH13303.1 - 4.9e-11 42.1 0.0 1.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH13303.1 - 2.3e-09 36.6 0.0 5.7e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 CEH13303.1 - 0.03 13.0 0.6 22 3.6 0.0 3.7 2 2 0 3 3 3 0 Nup133 N terminal like CRAL_TRIO PF00650.15 CEH13304.1 - 1e-30 106.3 0.0 1.7e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEH13304.1 - 2.3e-13 50.0 0.2 7.7e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CEH13304.1 - 1.8e-05 24.7 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Mucin PF01456.12 CEH13304.1 - 1.1 8.9 6.2 1.9 8.2 4.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DPM3 PF08285.6 CEH13306.1 - 2.7e-24 84.8 0.0 2.9e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Glyco_hydro_3 PF00933.16 CEH13307.1 - 4.9e-72 242.4 0.0 7.2e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CEH13307.1 - 1.7e-46 158.5 0.0 3.7e-46 157.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CEH13307.1 - 1e-23 83.0 0.3 1.9e-23 82.1 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Vir_act_alpha_C PF10400.4 CEH13308.1 - 0.0075 16.6 3.3 0.2 12.0 0.4 2.3 2 0 0 2 2 2 2 Virulence activator alpha C-term UPF0242 PF06785.6 CEH13310.1 - 0.012 14.2 0.2 0.013 14.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) IncA PF04156.9 CEH13310.1 - 0.063 12.8 4.7 0.075 12.6 3.0 1.3 1 1 0 1 1 1 0 IncA protein Myosin_tail_1 PF01576.14 CEH13310.1 - 0.082 10.6 2.2 0.096 10.3 1.5 1.0 1 0 0 1 1 1 0 Myosin tail PSCyt2 PF07583.6 CEH13310.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Oxysterol_BP PF01237.13 CEH13312.1 - 0.028 12.8 1.3 0.04 12.3 0.9 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein NIR_SIR PF01077.17 CEH13314.1 - 3.7e-29 101.1 0.1 7.8e-29 100.0 0.1 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 CEH13314.1 - 5.5e-22 78.6 0.1 8.9e-22 77.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 CEH13314.1 - 8.1e-13 47.9 0.0 1.8e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 CEH13314.1 - 1.1e-11 45.0 0.8 1.1e-11 45.0 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 CEH13314.1 - 2.3e-11 43.5 6.7 1.5e-10 40.9 2.9 2.7 3 0 0 3 3 3 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 CEH13314.1 - 5.8e-10 38.6 0.1 2.7e-09 36.4 0.0 2.2 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 CEH13314.1 - 1.1e-08 34.6 0.0 2.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 CEH13314.1 - 1e-05 25.7 0.3 0.0035 17.4 0.0 2.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEH13314.1 - 0.0038 16.9 1.4 2.4 7.9 0.0 3.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 CEH13314.1 - 0.016 14.1 0.0 0.033 13.0 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 CEH13314.1 - 0.17 11.9 1.6 11 6.0 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain Oxidored_molyb PF00174.14 CEH13315.1 - 5.9e-53 178.7 0.0 1.3e-52 177.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CEH13315.1 - 1.3e-45 154.2 0.1 2.7e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 CEH13315.1 - 1.5e-22 79.5 0.0 1.6e-21 76.2 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 CEH13315.1 - 6e-22 77.2 0.1 1.3e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 CEH13315.1 - 3e-21 76.0 0.0 7.1e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CEH13315.1 - 0.0017 18.2 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF607 PF04678.8 CEH13317.1 - 0.0099 15.8 1.4 0.014 15.2 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 bZIP_1 PF00170.16 CEH13317.1 - 0.015 15.2 0.6 0.015 15.2 0.4 2.9 2 1 1 3 3 3 0 bZIP transcription factor HOOK PF05622.7 CEH13317.1 - 0.17 9.6 8.0 0.23 9.2 5.5 1.1 1 0 0 1 1 1 0 HOOK protein DUF812 PF05667.6 CEH13317.1 - 0.19 10.2 6.1 0.28 9.6 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Lge1 PF11488.3 CEH13317.1 - 0.24 11.6 7.0 0.65 10.2 4.9 1.8 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Ly49 PF08391.5 CEH13317.1 - 0.54 10.4 3.9 0.95 9.6 2.7 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region TryThrA_C PF12319.3 CEH13317.1 - 2 7.5 10.3 0.12 11.5 3.0 1.8 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Bap31 PF05529.7 CEH13317.1 - 7.1 6.0 7.7 14 5.1 5.3 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Leu_zip PF15294.1 CEH13319.1 - 0.0076 15.3 0.3 0.012 14.7 0.2 1.2 1 0 0 1 1 1 1 Leucine zipper BLOC1_2 PF10046.4 CEH13319.1 - 0.0081 16.2 0.6 0.016 15.3 0.4 1.5 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.6 CEH13319.1 - 0.02 14.7 3.2 0.03 14.1 2.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 CEH13319.1 - 0.031 13.4 1.7 0.054 12.6 1.2 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 CEH13319.1 - 0.04 12.5 1.0 0.06 11.9 0.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.3 CEH13319.1 - 0.067 13.0 1.3 0.11 12.4 0.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2520 PF10728.4 CEH13319.1 - 0.11 12.0 0.8 0.63 9.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) Tet_JBP PF12851.2 CEH13320.1 - 2.8e-07 29.9 0.0 5.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Ribosomal_S5 PF00333.15 CEH13321.1 - 1.2e-28 98.5 2.5 3.9e-28 96.9 0.8 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CEH13321.1 - 6.7e-21 73.3 0.1 1.2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S10 PF00338.17 CEH13322.1 - 3.7e-30 103.6 0.2 4.3e-30 103.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GFA PF04828.9 CEH13323.1 - 0.0034 17.2 1.9 1.1 9.2 0.1 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Zn_Tnp_IS1595 PF12760.2 CEH13323.1 - 0.0062 16.3 7.1 0.36 10.6 0.3 2.2 1 1 1 2 2 2 2 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 CEH13323.1 - 0.014 14.6 1.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 CEH13323.1 - 0.016 15.0 3.6 0.063 13.0 2.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon DUF2845 PF11006.3 CEH13323.1 - 0.017 14.9 1.0 3.3 7.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2845) zf-C4pol PF14260.1 CEH13323.1 - 0.024 14.6 1.0 0.047 13.6 0.7 1.5 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Ribosomal_L37e PF01907.14 CEH13323.1 - 0.026 14.2 5.4 1.4 8.7 0.4 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e zf-CCHC PF00098.18 CEH13323.1 - 0.053 13.4 3.0 7.3 6.7 0.2 2.7 2 0 0 2 2 2 0 Zinc knuckle DUF2688 PF10892.3 CEH13323.1 - 0.057 13.1 3.2 4.1 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Zn-ribbon_8 PF09723.5 CEH13323.1 - 0.092 12.7 1.9 7.8 6.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-RanBP PF00641.13 CEH13323.1 - 0.24 10.5 3.4 7.3 5.7 0.2 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Ribosomal_S14 PF00253.16 CEH13323.1 - 0.39 10.1 8.4 2.2 7.7 0.7 2.2 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Ogr_Delta PF04606.7 CEH13323.1 - 1.1 8.9 4.3 13 5.5 0.2 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger RNA_POL_M_15KD PF02150.11 CEH13323.1 - 1.7 8.3 4.9 13 5.6 0.3 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Ribosomal_S27 PF01599.14 CEH13323.1 - 1.9 8.3 7.6 8.6 6.2 0.4 2.7 3 0 0 3 3 3 0 Ribosomal protein S27a Ribosomal_L32p PF01783.18 CEH13323.1 - 4.2 7.6 8.2 12 6.1 1.6 2.9 1 1 2 3 3 3 0 Ribosomal L32p protein family zf-C2H2_3 PF13878.1 CEH13323.1 - 4.8 6.8 5.3 25 4.5 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO RRN7 PF11781.3 CEH13323.1 - 5.8 6.4 6.9 20 4.8 0.5 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 FYVE PF01363.16 CEH13323.1 - 7.7 6.5 8.7 40 4.1 6.1 2.1 1 1 0 1 1 1 0 FYVE zinc finger CBFD_NFYB_HMF PF00808.18 CEH13324.1 - 1.8e-18 66.3 0.8 2.6e-18 65.8 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEH13324.1 - 5.6e-12 45.5 0.1 8.9e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DnaJ PF00226.26 CEH13325.1 - 1.7e-19 69.2 0.3 1.9e-18 65.9 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain Sec3_C PF09763.4 CEH13325.1 - 0.067 11.3 0.4 0.088 10.9 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 RRM_6 PF14259.1 CEH13325.1 - 0.15 12.0 0.0 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U79_P34 PF03064.11 CEH13325.1 - 1.8 8.0 8.8 2.9 7.3 6.1 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 IncA PF04156.9 CEH13325.1 - 1.9 8.0 5.9 2.9 7.4 4.1 1.2 1 0 0 1 1 1 0 IncA protein P21-Arc PF04062.9 CEH13326.1 - 7.4e-76 253.8 0.0 8.2e-76 253.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit HA2 PF04408.18 CEH13327.1 - 1.1e-25 89.6 0.0 5.5e-25 87.3 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CEH13327.1 - 6.6e-23 80.7 0.0 1.7e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CEH13327.1 - 1.1e-13 50.8 0.0 2.9e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEH13327.1 - 1.4e-07 31.1 0.0 3.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEH13327.1 - 3.3e-05 24.0 0.1 8.8e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CEH13327.1 - 0.0042 16.0 0.0 0.0074 15.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 CEH13327.1 - 0.0075 16.3 0.0 0.025 14.6 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain SRP54 PF00448.17 CEH13327.1 - 0.012 15.1 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KaiC PF06745.8 CEH13327.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 CEH13327.1 - 0.015 15.2 0.0 0.094 12.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CEH13327.1 - 0.034 13.5 0.0 0.13 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CEH13327.1 - 0.036 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 CEH13327.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.10 CEH13327.1 - 0.041 13.6 0.0 8.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 CEH13327.1 - 0.049 12.4 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 CEH13327.1 - 0.057 13.0 0.1 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Myosin_head PF00063.16 CEH13327.1 - 0.097 10.6 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) UPF0079 PF02367.12 CEH13327.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DOR PF14839.1 CEH13327.1 - 0.17 11.6 11.2 0.69 9.6 0.8 2.8 2 0 0 2 2 2 0 DOR family Nop14 PF04147.7 CEH13328.1 - 6.3e-219 729.0 0.3 7.8e-219 728.7 0.2 1.1 1 0 0 1 1 1 1 Nop14-like family Proteasome PF00227.21 CEH13329.1 - 7e-34 116.7 0.0 8.4e-34 116.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SAMP PF05924.6 CEH13329.1 - 0.057 12.5 0.6 0.097 11.8 0.4 1.4 1 0 0 1 1 1 0 SAMP Motif PIG-P PF08510.7 CEH13330.1 - 4.6e-26 90.9 0.0 9.4e-26 89.9 0.0 1.5 1 1 0 1 1 1 1 PIG-P Per1 PF04080.8 CEH13330.1 - 0.16 11.3 0.3 0.21 10.9 0.2 1.1 1 0 0 1 1 1 0 Per1-like DPM2 PF07297.7 CEH13330.1 - 1.6 9.0 4.7 3.1 8.1 3.3 1.4 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Pyr_redox_dim PF02852.17 CEH13331.1 - 5.7e-39 132.5 0.1 1.3e-38 131.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CEH13331.1 - 6.1e-35 120.9 23.3 6e-34 117.6 15.2 3.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEH13331.1 - 2.9e-19 69.2 9.2 6.9e-17 61.6 1.0 3.7 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEH13331.1 - 7.3e-11 41.7 0.5 7.3e-11 41.7 0.4 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CEH13331.1 - 1e-09 38.7 1.2 5.2e-05 23.3 0.2 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH13331.1 - 7.9e-08 32.2 3.4 0.001 19.0 0.2 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CEH13331.1 - 7.8e-07 28.2 2.6 7.8e-07 28.2 1.8 2.9 4 0 0 4 4 4 1 FAD binding domain GIDA PF01134.17 CEH13331.1 - 1.1e-06 27.7 14.0 2.9e-06 26.3 3.6 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 CEH13331.1 - 1.5e-06 27.5 2.1 0.00015 20.9 0.0 2.4 2 0 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.16 CEH13331.1 - 3.1e-05 23.6 4.6 0.01 15.4 0.1 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 CEH13331.1 - 5.7e-05 21.7 12.2 0.0005 18.6 0.6 4.1 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.1 CEH13331.1 - 7.2e-05 21.8 0.1 0.45 9.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 CEH13331.1 - 0.0011 18.0 13.4 0.014 14.3 0.1 3.9 3 1 1 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CEH13331.1 - 0.0041 16.2 9.9 0.16 10.9 0.5 3.2 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.7 CEH13331.1 - 0.54 9.1 1.7 1.1 8.0 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 CEH13331.1 - 0.62 9.6 6.7 0.095 12.3 0.5 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CEH13331.1 - 3.9 7.7 7.2 1.2 9.3 0.6 2.9 3 1 0 3 3 2 0 Putative NAD(P)-binding MFS_1 PF07690.11 CEH13332.1 - 3.4e-10 39.1 24.7 5.7e-10 38.4 11.3 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CEH13332.1 - 4.9e-09 35.0 0.9 4.9e-09 35.0 0.6 2.4 3 0 0 3 3 3 2 MFS/sugar transport protein DNA_pol_E_B PF04042.11 CEH13333.1 - 5.6e-29 100.8 0.1 8.6e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 CEH13333.1 - 6e-28 98.0 0.0 1e-27 97.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Na_Ca_ex PF01699.19 CEH13334.1 - 5.7e-41 139.3 37.6 3.4e-24 85.0 7.0 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Macoilin PF09726.4 CEH13334.1 - 0.032 12.5 4.1 0.062 11.5 2.8 1.4 1 0 0 1 1 1 0 Transmembrane protein Sec10 PF07393.6 CEH13334.1 - 0.22 9.6 3.5 0.31 9.1 2.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Trypan_PARP PF05887.6 CEH13334.1 - 0.26 11.1 14.0 0.06 13.1 6.7 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Dicty_REP PF05086.7 CEH13334.1 - 4.4 4.9 6.1 6.2 4.4 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Herpes_pp85 PF04637.7 CEH13334.1 - 5.9 5.0 5.2 10 4.3 3.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DEAD PF00270.24 CEH13335.1 - 8.3e-44 149.0 0.0 1.5e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH13335.1 - 4.2e-26 90.6 0.0 8.7e-26 89.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH13335.1 - 0.0036 17.1 0.0 0.11 12.3 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Dsh_C PF12316.3 CEH13335.1 - 2.2 8.3 13.7 4.3 7.4 9.5 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal PBP1_TM PF14812.1 CEH13335.1 - 4.8 7.5 9.4 14 6.0 0.5 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L18ae PF01775.12 CEH13336.1 - 4.5e-59 197.7 0.4 5.7e-59 197.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Cpn60_TCP1 PF00118.19 CEH13337.1 - 3e-142 474.6 9.3 3.6e-142 474.4 6.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 CEH13337.1 - 0.0011 18.1 0.0 0.0029 16.8 0.0 1.7 1 0 0 1 1 1 1 Telomere recombination dCMP_cyt_deam_1 PF00383.17 CEH13338.1 - 4e-24 84.1 0.7 8e-24 83.2 0.5 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 CEH13338.1 - 0.014 16.1 0.1 0.031 15.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CEH13338.1 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CEH13338.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CEH13338.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CEH13338.1 - 0.18 11.5 0.1 0.43 10.2 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_L1 PF00687.16 CEH13339.1 - 5.2e-49 166.5 1.6 6e-49 166.3 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L23eN PF03939.8 CEH13340.1 - 2e-21 75.7 9.5 2e-21 75.7 6.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 CEH13340.1 - 1.6e-14 53.5 1.8 2.1e-14 53.2 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 TusA PF01206.12 CEH13340.1 - 0.021 14.4 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 Sulfurtransferase TusA DASH_Dam1 PF08653.5 CEH13341.1 - 4.9e-23 80.6 0.2 7.5e-23 80.0 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 Ribosomal_L37ae PF01780.14 CEH13342.1 - 1.6e-40 136.8 8.7 1.8e-40 136.7 6.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 CEH13342.1 - 0.0012 18.6 3.5 0.0019 17.9 2.4 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 CEH13342.1 - 0.0071 16.0 4.4 0.07 12.8 0.2 2.3 1 1 1 2 2 2 2 BED zinc finger OrfB_Zn_ribbon PF07282.6 CEH13342.1 - 0.019 14.5 1.8 0.028 14.0 1.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 CEH13342.1 - 0.029 13.8 3.1 0.28 10.6 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 CEH13342.1 - 0.082 12.8 1.6 0.59 10.1 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Rsm1 PF08600.5 CEH13342.1 - 0.11 12.3 0.5 0.15 11.9 0.4 1.2 1 0 0 1 1 1 0 Rsm1-like Elf1 PF05129.8 CEH13342.1 - 0.21 11.2 2.5 0.34 10.6 1.8 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.10 CEH13342.1 - 0.27 10.8 1.5 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.1 CEH13342.1 - 0.28 11.5 6.0 2.4 8.5 0.6 2.2 1 1 1 2 2 2 0 Zinc-finger double domain Tnp_zf-ribbon_2 PF13842.1 CEH13342.1 - 1.1 9.7 4.4 1.6 9.1 2.3 1.8 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DUF2235 PF09994.4 CEH13344.1 - 4.1e-54 183.8 0.1 6.3e-54 183.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3850 PF12961.2 CEH13344.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) HSF_DNA-bind PF00447.12 CEH13345.1 - 4e-19 68.7 0.0 6.3e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Adaptin_N PF01602.15 CEH13348.1 - 1.9e-94 316.8 5.9 3.7e-67 226.8 4.2 2.2 1 1 1 2 2 2 2 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CEH13348.1 - 5.9e-61 203.9 0.0 1.7e-60 202.4 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CEH13348.1 - 1.8e-59 199.4 0.1 4.4e-59 198.1 0.1 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CEH13348.1 - 6.8e-14 51.9 3.5 0.00063 19.9 0.2 5.5 2 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 CEH13348.1 - 2.8e-10 40.3 6.6 0.0033 17.2 0.6 5.2 3 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CEH13348.1 - 2.7e-07 30.1 0.5 0.044 13.8 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 CEH13348.1 - 0.00023 21.5 0.5 8.8 6.9 0.0 5.2 4 1 1 5 5 5 2 HEAT-like repeat Ribosomal_L16 PF00252.13 CEH13350.1 - 5.3e-30 103.9 0.1 6.8e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PCI PF01399.22 CEH13352.1 - 0.00044 20.5 0.0 0.0015 18.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain DUF3433 PF11915.3 CEH13352.1 - 0.1 12.7 0.2 0.65 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) GCN5L1 PF06320.8 CEH13352.1 - 0.11 12.3 1.5 0.21 11.3 0.2 1.9 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) MxiH PF09392.5 CEH13352.1 - 0.38 11.3 4.0 0.38 11.3 0.2 2.4 1 1 1 2 2 2 0 Type III secretion needle MxiH like AAA PF00004.24 CEH13353.1 - 5.2e-44 149.6 0.0 9.2e-44 148.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CEH13353.1 - 1e-07 32.0 0.0 2.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CEH13353.1 - 2.1e-06 27.5 0.0 1.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEH13353.1 - 2.4e-06 27.6 0.1 9e-06 25.7 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 CEH13353.1 - 9.2e-06 25.8 0.0 0.00035 20.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH13353.1 - 4.5e-05 23.1 0.1 0.00015 21.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CEH13353.1 - 7.6e-05 23.5 0.0 0.00027 21.7 0.0 2.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CEH13353.1 - 0.00012 21.2 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CEH13353.1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CEH13353.1 - 0.0011 17.7 0.0 0.0024 16.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 CEH13353.1 - 0.0018 18.1 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CEH13353.1 - 0.0026 17.6 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEH13353.1 - 0.0028 16.7 0.0 0.006 15.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.11 CEH13353.1 - 0.0034 16.6 0.0 0.071 12.3 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.1 CEH13353.1 - 0.0036 17.2 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CEH13353.1 - 0.0064 15.6 0.1 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CEH13353.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2072 PF09845.4 CEH13353.1 - 0.012 15.5 0.1 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) AAA_18 PF13238.1 CEH13353.1 - 0.013 15.8 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CEH13353.1 - 0.019 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 CEH13353.1 - 0.022 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CEH13353.1 - 0.023 14.1 0.1 0.1 12.0 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.8 CEH13353.1 - 0.028 13.3 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 CEH13353.1 - 0.029 13.7 0.1 0.09 12.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 CEH13353.1 - 0.036 14.2 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CEH13353.1 - 0.044 13.4 0.0 0.59 9.7 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 CEH13353.1 - 0.052 12.4 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CEH13353.1 - 0.056 13.4 0.0 0.19 11.7 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 CEH13353.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Cnd3 PF12719.2 CEH13354.1 - 3.6e-65 219.8 0.2 9.6e-65 218.4 0.0 1.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 CEH13354.1 - 0.014 15.6 6.7 0.7 10.2 0.0 4.3 5 0 0 5 5 5 0 HEAT repeats Pcc1 PF09341.5 CEH13355.1 - 2.2e-15 56.4 0.2 2.9e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 ABC_tran PF00005.22 CEH13356.1 - 2.9e-33 115.0 0.1 1.7e-16 60.7 0.0 3.1 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 CEH13356.1 - 1.1e-12 47.2 5.8 1.1e-12 47.2 4.0 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CEH13356.1 - 3.2e-12 47.0 7.5 0.052 13.5 0.0 4.3 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 CEH13356.1 - 1.7e-11 43.8 4.7 0.00096 18.4 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CEH13356.1 - 1.4e-06 28.4 0.0 0.0033 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CEH13356.1 - 4.4e-06 25.9 0.9 0.089 11.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA PF00004.24 CEH13356.1 - 4.7e-06 26.8 0.0 0.016 15.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 CEH13356.1 - 7.3e-06 25.2 1.7 1.3 8.0 0.0 4.6 5 0 0 5 5 5 1 AAA ATPase domain AAA_29 PF13555.1 CEH13356.1 - 1.2e-05 24.7 0.3 0.041 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CEH13356.1 - 0.00024 21.8 0.4 1.4 9.7 0.1 2.8 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 CEH13356.1 - 0.00027 20.6 1.0 0.034 13.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain VirE PF05272.6 CEH13356.1 - 0.00047 19.6 0.0 0.43 10.0 0.0 2.4 2 0 0 2 2 2 2 Virulence-associated protein E Miro PF08477.8 CEH13356.1 - 0.00051 20.5 0.0 0.76 10.2 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 CEH13356.1 - 0.00054 19.4 0.1 0.45 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Fer4 PF00037.22 CEH13356.1 - 0.00061 19.2 4.0 0.00061 19.2 2.8 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 CEH13356.1 - 0.00092 19.5 7.6 0.004 17.5 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain MobB PF03205.9 CEH13356.1 - 0.0013 18.4 0.5 0.46 10.1 0.0 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CEH13356.1 - 0.0015 18.4 0.0 0.21 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CEH13356.1 - 0.0015 18.6 0.0 0.49 10.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 CEH13356.1 - 0.0016 18.4 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 CEH13356.1 - 0.0017 18.1 0.0 2.8 7.9 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_21 PF14697.1 CEH13356.1 - 0.002 17.9 11.5 0.0044 16.8 8.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_18 PF13238.1 CEH13356.1 - 0.0044 17.3 0.6 0.92 9.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 CEH13356.1 - 0.0053 16.2 1.6 0.55 9.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.1 CEH13356.1 - 0.0064 16.8 3.6 0.034 14.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CEH13356.1 - 0.0078 15.8 0.3 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_6 PF12837.2 CEH13356.1 - 0.013 15.3 2.9 0.013 15.3 2.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_16 PF13484.1 CEH13356.1 - 0.013 16.2 5.1 0.029 15.0 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_14 PF13173.1 CEH13356.1 - 0.014 15.3 0.9 12 5.7 0.0 3.9 4 1 1 5 5 5 0 AAA domain Rad17 PF03215.10 CEH13356.1 - 0.022 13.4 0.0 1.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 CEH13356.1 - 0.023 14.6 0.0 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 CEH13356.1 - 0.038 14.2 2.0 0.038 14.2 1.4 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain HflK_N PF12221.3 CEH13356.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Thymidylate_kin PF02223.12 CEH13356.1 - 0.065 12.6 0.4 8.4 5.7 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase NB-ARC PF00931.17 CEH13356.1 - 0.096 11.5 0.0 3.4 6.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 CEH13356.1 - 0.12 12.0 1.6 1.9 8.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CEH13356.1 - 0.14 11.6 1.0 8.2 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 CEH13356.1 - 0.16 11.5 0.8 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 CEH13356.1 - 0.77 9.8 10.0 0.54 10.3 1.3 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 CEH13356.1 - 1.8 8.4 17.1 0.19 11.5 2.0 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Cyclin PF08613.6 CEH13357.1 - 4.1e-10 40.2 0.0 2.4e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Cyclin SAD_SRA PF02182.12 CEH13358.1 - 4.4e-23 81.2 0.0 6.3e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain YqzE PF14038.1 CEH13358.1 - 9.1 6.1 8.1 0.35 10.6 0.2 2.3 2 0 0 2 2 2 0 YqzE-like protein Ribosomal_L3 PF00297.17 CEH13360.1 - 3.4e-111 370.8 5.8 4.1e-111 370.5 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Bac_rhamnosid_N PF08531.5 CEH13360.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Gly_transf_sug PF04488.10 CEH13362.1 - 9.6e-20 70.8 0.0 1.6e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CEH13362.1 - 0.0058 15.1 2.4 0.059 11.8 0.2 2.4 3 0 0 3 3 3 2 TcdA/TcdB catalytic glycosyltransferase domain SIM_C PF06621.7 CEH13363.1 - 0.00088 18.9 0.3 0.0011 18.6 0.2 1.1 1 0 0 1 1 1 1 Single-minded protein C-terminus Prok-TraM PF09228.5 CEH13363.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Histone PF00125.19 CEH13364.1 - 7.1e-26 90.1 0.0 8.8e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CEH13364.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEH13365.1 - 9.6e-23 80.1 0.5 1.8e-22 79.2 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CEH13365.1 - 1.5e-06 28.1 0.1 3.4e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CEH13365.1 - 0.00023 21.3 0.0 0.00042 20.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 CEH13365.1 - 0.034 14.6 0.6 0.048 14.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 CEH13365.1 - 0.058 12.8 0.6 0.22 10.9 0.4 1.8 1 1 0 1 1 1 0 Replication protein C N-terminal domain Complex1_LYR PF05347.10 CEH13366.1 - 6.4e-07 29.0 0.2 1.1e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CEH13366.1 - 1.1e-05 25.5 0.2 2e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DUF826 PF05696.6 CEH13366.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Ribosomal_L16 PF00252.13 CEH13367.1 - 3.1e-15 56.0 0.1 9.3e-09 35.1 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein L16p/L10e zf-ZPR1 PF03367.8 CEH13368.1 - 1.5e-100 333.0 0.0 3.3e-50 169.3 0.0 2.8 2 1 0 2 2 2 2 ZPR1 zinc-finger domain Lar_restr_allev PF14354.1 CEH13368.1 - 0.085 13.1 1.9 4 7.8 0.0 3.1 2 1 1 3 3 3 0 Restriction alleviation protein Lar DZR PF12773.2 CEH13368.1 - 6.3 6.7 6.6 10 6.0 0.1 3.0 2 1 0 2 2 2 0 Double zinc ribbon Tim17 PF02466.14 CEH13369.1 - 1.4e-23 83.3 7.6 2.3e-23 82.6 5.3 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_S8e PF01201.17 CEH13371.1 - 2.1e-33 115.2 9.9 4.7e-33 114.1 6.9 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Grp1_Fun34_YaaH PF01184.14 CEH13373.1 - 9.1e-49 165.6 17.5 1.1e-48 165.3 12.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Herpes_LMP1 PF05297.6 CEH13373.1 - 0.31 9.9 1.9 0.53 9.1 1.3 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) AAA PF00004.24 CEH13374.1 - 1.2e-90 300.5 0.0 7.9e-47 158.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CEH13374.1 - 2.5e-14 52.9 0.0 9.1e-08 31.4 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CEH13374.1 - 9e-13 48.6 1.1 7.9e-05 22.7 0.0 3.5 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 CEH13374.1 - 2.3e-11 43.9 0.6 0.0055 16.8 0.0 4.6 2 2 1 3 3 2 2 AAA domain AAA_5 PF07728.9 CEH13374.1 - 9.6e-11 41.5 0.8 0.00091 18.9 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CEH13374.1 - 1.6e-10 41.1 0.0 0.00098 19.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CEH13374.1 - 2.5e-09 37.1 0.0 0.0019 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CEH13374.1 - 2.8e-08 33.6 0.0 0.0098 15.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CEH13374.1 - 4.8e-08 33.8 0.0 0.0089 16.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 CEH13374.1 - 1.7e-07 30.3 0.3 0.0037 16.0 0.0 2.9 2 1 1 3 3 3 2 TIP49 C-terminus Mg_chelatase PF01078.16 CEH13374.1 - 6.5e-07 28.7 0.5 0.03 13.4 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CEH13374.1 - 7.4e-07 28.4 0.0 0.014 14.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 CEH13374.1 - 1.7e-06 27.7 1.0 0.07 12.7 0.0 4.1 3 1 1 4 4 4 1 NACHT domain RNA_helicase PF00910.17 CEH13374.1 - 2.3e-06 27.7 0.0 0.062 13.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 CEH13374.1 - 3.8e-06 26.5 11.6 0.01 15.5 0.0 5.2 5 0 0 5 5 5 2 Part of AAA domain IstB_IS21 PF01695.12 CEH13374.1 - 5.3e-06 25.9 0.8 0.057 12.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 CEH13374.1 - 1.1e-05 24.9 6.2 0.25 10.7 0.1 4.6 2 2 3 5 5 5 1 AAA domain Sigma54_activ_2 PF14532.1 CEH13374.1 - 1.5e-05 25.1 0.0 0.05 13.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 CEH13374.1 - 1.7e-05 24.4 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CEH13374.1 - 0.00011 22.5 0.0 0.17 12.2 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 CEH13374.1 - 0.00012 22.0 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CEH13374.1 - 0.00015 21.2 0.0 0.24 10.8 0.0 3.5 3 1 0 3 3 3 1 Sigma-54 interaction domain KaiC PF06745.8 CEH13374.1 - 0.00016 20.8 0.1 2.9 6.9 0.0 3.2 3 0 0 3 3 3 1 KaiC AAA_18 PF13238.1 CEH13374.1 - 0.00046 20.4 0.0 0.58 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CEH13374.1 - 0.0012 17.7 0.0 1 8.1 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain SKI PF01202.17 CEH13374.1 - 0.0019 18.1 0.1 0.66 9.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Viral_helicase1 PF01443.13 CEH13374.1 - 0.0021 17.5 0.0 0.81 9.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.1 CEH13374.1 - 0.0025 17.7 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 2 Cytidylate kinase-like family Rad17 PF03215.10 CEH13374.1 - 0.0027 16.4 0.0 1 7.9 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 CEH13374.1 - 0.0031 16.4 0.0 0.033 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 CEH13374.1 - 0.006 15.8 0.3 3 7.0 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.1 CEH13374.1 - 0.0074 15.8 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CEH13374.1 - 0.0087 15.6 0.4 4.1 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 CEH13374.1 - 0.011 15.6 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 CEH13374.1 - 0.013 15.2 0.0 12 5.5 0.0 3.5 2 2 2 4 4 4 0 Archaeal ATPase ATP-synt_ab PF00006.20 CEH13374.1 - 0.021 14.3 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AFG1_ATPase PF03969.11 CEH13374.1 - 0.029 13.1 0.0 1.2 7.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_24 PF13479.1 CEH13374.1 - 0.03 13.9 0.1 7.2 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 CEH13374.1 - 0.063 12.1 0.0 5.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 CEH13374.1 - 0.075 12.7 0.1 5.2 6.7 0.0 2.6 3 0 0 3 3 2 0 NTPase UPF0079 PF02367.12 CEH13374.1 - 0.22 11.1 0.1 20 4.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 CEH13374.1 - 0.29 10.0 0.1 11 4.8 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PUB PF09409.5 CEH13375.1 - 2.2e-12 46.5 0.0 3.8e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 PUB domain Thioredoxin_4 PF13462.1 CEH13375.1 - 0.62 10.0 4.2 0.52 10.3 0.2 2.3 2 1 0 2 2 2 0 Thioredoxin PV-1 PF06637.6 CEH13375.1 - 9.5 4.6 16.4 0.32 9.5 5.0 2.1 2 0 0 2 2 2 0 PV-1 protein (PLVAP) EamA PF00892.15 CEH13376.1 - 6.4e-06 26.2 4.7 6.4e-06 26.2 3.3 3.3 3 1 0 3 3 3 1 EamA-like transporter family Mating_C PF12737.2 CEH13376.1 - 0.00017 20.6 1.1 0.00019 20.4 0.8 1.1 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 DUF914 PF06027.7 CEH13376.1 - 0.0022 16.8 7.2 0.0087 14.9 1.6 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) PgpA PF04608.8 CEH13376.1 - 0.22 11.3 3.8 0.099 12.4 0.5 2.0 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A PepSY_TM PF03929.11 CEH13376.1 - 1.4 9.4 8.4 0.45 11.0 0.2 4.0 3 0 0 3 3 3 0 PepSY-associated TM helix DUF1003 PF06210.6 CEH13376.1 - 1.5 8.7 3.2 0.43 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) UPF0203 PF05254.7 CEH13377.1 - 0.00018 21.2 3.3 0.00051 19.8 2.3 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.8 CEH13377.1 - 0.004 17.0 3.1 0.043 13.7 2.0 2.0 1 1 1 2 2 2 1 CHCH domain COX17 PF05051.8 CEH13377.1 - 0.0053 16.7 1.1 0.0074 16.2 0.8 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 CEH13377.1 - 0.0055 16.4 3.0 0.93 9.3 0.8 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.3 CEH13377.1 - 0.084 13.0 1.8 0.092 12.8 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) SNAP PF14938.1 CEH13378.1 - 2.6e-87 292.5 12.1 3e-87 292.3 8.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CEH13378.1 - 2.1e-06 27.5 5.1 1.8e-05 24.5 0.7 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CEH13378.1 - 5.5e-06 25.9 7.7 0.23 11.1 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_7 PF13176.1 CEH13378.1 - 0.0056 16.3 7.0 2.2 8.2 0.2 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 CEH13378.1 - 0.0081 16.0 6.3 3.9 7.6 0.1 5.4 3 3 2 6 6 6 1 Tetratricopeptide repeat Spatacsin_C PF14649.1 CEH13378.1 - 0.015 14.2 1.2 0.063 12.1 0.0 2.0 2 0 0 2 2 2 0 Spatacsin C-terminus GDE_C PF06202.9 CEH13378.1 - 0.018 13.7 0.1 0.023 13.4 0.1 1.1 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase TPR_1 PF00515.23 CEH13378.1 - 0.019 14.5 3.0 6.7 6.5 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CEH13378.1 - 0.027 15.1 15.6 0.86 10.3 0.0 4.5 3 1 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEH13378.1 - 0.063 13.7 6.3 20 5.9 0.1 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 CEH13378.1 - 0.23 11.7 5.1 0.88 9.9 0.1 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CEH13378.1 - 0.39 11.4 8.4 8.4 7.3 0.3 5.2 4 2 2 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.7 CEH13378.1 - 0.64 10.7 6.2 2.4 8.9 0.2 3.6 3 0 0 3 3 3 0 Sel1 repeat DUF349 PF03993.7 CEH13378.1 - 2.2 8.4 6.5 0.7 10.1 0.6 2.9 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) SNF2_N PF00176.18 CEH13379.1 - 8.4e-82 274.3 0.2 8.4e-82 274.3 0.2 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEH13379.1 - 2e-17 62.7 0.0 3.8e-16 58.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.8 CEH13379.1 - 1.2e-16 60.2 6.7 1.2e-16 60.2 4.6 3.3 4 0 0 4 4 4 1 HSA Bromodomain PF00439.20 CEH13379.1 - 2.5e-14 52.9 0.1 7.6e-14 51.3 0.0 1.9 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 CEH13379.1 - 4.9e-13 49.0 2.1 4.9e-13 49.0 1.4 3.3 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 CEH13379.1 - 2e-09 36.6 0.0 2e-09 36.6 0.0 3.5 3 0 0 3 3 3 1 QLQ 2-Hacid_dh_C PF02826.14 CEH13381.1 - 8.2e-29 99.9 0.0 1.6e-28 99.0 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CEH13381.1 - 2.2e-05 24.5 0.0 3.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 CEH13381.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 CEH13381.1 - 0.02 15.1 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.1 CEH13381.1 - 0.025 14.8 0.0 0.1 12.9 0.0 2.0 1 1 0 1 1 1 0 XdhC Rossmann domain Fumerase_C PF05683.7 CEH13382.1 - 0.0097 15.0 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Fumarase C-terminus PVL_ORF50 PF07768.6 CEH13383.1 - 0.094 12.7 2.7 0.18 11.8 1.9 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family Complex1_LYR PF05347.10 CEH13383.1 - 0.87 9.4 3.8 0.41 10.4 0.7 1.9 2 0 0 2 2 2 0 Complex 1 protein (LYR family) adh_short_C2 PF13561.1 CEH13384.1 - 7.4e-30 104.4 0.0 8.6e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEH13384.1 - 1e-11 45.0 0.1 4e-11 43.1 0.1 1.8 1 1 1 2 2 2 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.14 CEH13384.1 - 0.00078 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.5 CEH13384.1 - 0.0016 18.1 0.0 0.0043 16.7 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 CEH13384.1 - 0.0095 15.9 0.1 0.033 14.2 0.1 2.0 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CEH13384.1 - 0.014 15.1 0.5 0.024 14.4 0.4 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 CEH13384.1 - 0.025 14.8 0.0 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Oxidored_nitro PF00148.14 CEH13384.1 - 0.027 13.1 0.0 0.058 12.0 0.0 1.5 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase P_proprotein PF01483.15 CEH13384.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Proprotein convertase P-domain Citrate_synt PF00285.16 CEH13386.1 - 6.8e-18 64.5 0.0 7.6e-16 57.7 0.0 2.7 1 1 1 2 2 2 1 Citrate synthase Ligase_CoA PF00549.14 CEH13386.1 - 5.8e-15 55.2 0.1 1e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 CEH13386.1 - 7.6e-11 42.3 0.0 1.6e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 CEH13386.1 - 2.9e-07 30.0 0.0 5.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 CEH13386.1 - 5.2e-06 26.1 0.0 1.5e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.1 CEH13386.1 - 0.0033 16.6 0.0 0.014 14.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Frag1 PF10277.4 CEH13387.1 - 3.5e-37 127.9 16.3 4.1e-37 127.7 11.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SLAC1 PF03595.12 CEH13387.1 - 0.00047 18.9 9.5 0.00078 18.1 6.6 1.3 1 0 0 1 1 1 1 Voltage-dependent anion channel Cation_ATPase_C PF00689.16 CEH13387.1 - 0.012 15.1 11.8 0.087 12.3 1.0 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Pox_A14 PF05767.7 CEH13387.1 - 0.023 14.6 3.7 0.023 14.6 2.6 2.2 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF1673 PF07895.6 CEH13387.1 - 0.1 12.0 7.2 0.11 12.0 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) DUF1345 PF07077.6 CEH13387.1 - 0.13 11.7 9.0 0.084 12.3 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) Yip1 PF04893.12 CEH13387.1 - 0.21 11.0 13.6 0.073 12.5 6.1 2.3 1 1 1 2 2 2 0 Yip1 domain DUF998 PF06197.8 CEH13387.1 - 0.25 10.6 16.6 0.4 9.9 10.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF998) MASE1 PF05231.9 CEH13387.1 - 0.8 8.6 13.2 0.25 10.3 6.5 1.9 1 1 1 2 2 2 0 MASE1 Ndc1_Nup PF09531.5 CEH13387.1 - 5.2 5.3 10.4 4.2 5.6 1.5 2.1 1 1 1 2 2 2 0 Nucleoporin protein Ndc1-Nup E1_dh PF00676.15 CEH13388.1 - 7.9e-113 376.1 0.2 9.6e-113 375.8 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CEH13388.1 - 4.7e-05 22.4 0.0 8.2e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 CEH13388.1 - 0.0028 17.2 1.4 0.0028 17.2 1.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GTP_cyclohydroI PF01227.17 CEH13391.1 - 2e-73 245.4 0.2 2.8e-73 244.9 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CEH13391.1 - 0.0076 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein HATPase_c_2 PF13581.1 CEH13391.1 - 0.063 13.0 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MFS_1 PF07690.11 CEH13392.1 - 4.2e-34 117.8 41.8 6.3e-34 117.2 29.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Leader_Erm PF08253.6 CEH13392.1 - 0.0082 15.5 0.9 0.021 14.2 0.7 1.7 1 0 0 1 1 1 1 Erm Leader peptide 2-oxoacid_dh PF00198.18 CEH13393.1 - 6e-79 264.5 0.0 7.9e-79 264.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CEH13393.1 - 1.4e-18 66.3 0.7 3.7e-18 64.9 0.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CEH13393.1 - 8.6e-18 63.6 0.9 2.7e-17 62.0 0.6 2.0 1 0 0 1 1 1 1 e3 binding domain DUF3597 PF12200.3 CEH13393.1 - 5.6 7.3 11.2 1.2 9.5 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) AMPKBI PF04739.10 CEH13394.1 - 7.8e-12 44.9 0.0 1.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4399 PF14347.1 CEH13394.1 - 0.04 13.9 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Ndc80_HEC PF03801.8 CEH13395.1 - 4.4e-31 107.4 0.0 1.3e-30 105.9 0.0 1.8 1 1 1 2 2 2 1 HEC/Ndc80p family DUF3584 PF12128.3 CEH13395.1 - 1.4 6.1 37.3 0.31 8.3 8.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_12 PF13087.1 CEH13396.1 - 3.2e-52 176.8 0.0 5e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CEH13396.1 - 1.5e-49 168.7 0.0 4.2e-49 167.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH13396.1 - 4.8e-15 55.0 4.4 8.6e-13 47.8 1.1 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 CEH13396.1 - 2.4e-11 43.5 0.2 2.2e-08 33.9 0.1 3.2 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CEH13396.1 - 1.8e-06 27.6 0.6 0.65 9.4 0.0 3.5 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CEH13396.1 - 1.7e-05 24.2 0.2 8.2e-05 22.0 0.0 2.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 CEH13396.1 - 0.0029 17.6 1.6 0.039 13.9 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain PhoH PF02562.11 CEH13396.1 - 0.0065 15.7 0.1 0.018 14.2 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein UvrD_C_2 PF13538.1 CEH13396.1 - 0.099 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 CEH13396.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CEH13396.1 - 0.14 11.9 0.0 0.42 10.4 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 CEH13397.1 - 7.9e-42 142.5 0.0 1.2e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEH13397.1 - 5e-07 29.8 0.0 2.7e-05 24.2 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 CEH13397.1 - 5.2e-07 29.4 0.1 6.2e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CEH13397.1 - 2e-06 27.8 0.1 6.7e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CEH13397.1 - 5e-06 26.6 0.0 0.00066 19.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEH13397.1 - 7.4e-06 25.1 0.0 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CEH13397.1 - 8.8e-05 22.1 0.1 0.00019 21.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CEH13397.1 - 0.00025 21.8 1.1 0.00082 20.1 0.3 2.4 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CEH13397.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CEH13397.1 - 0.0023 16.9 0.0 0.004 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CEH13397.1 - 0.0023 17.8 0.0 0.0049 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CEH13397.1 - 0.0033 16.6 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CEH13397.1 - 0.0038 16.6 0.1 0.007 15.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CEH13397.1 - 0.0038 16.0 0.0 0.0062 15.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 CEH13397.1 - 0.0052 17.0 0.4 0.02 15.1 0.0 2.3 3 0 0 3 3 1 1 AAA domain AAA_28 PF13521.1 CEH13397.1 - 0.0083 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CEH13397.1 - 0.0086 15.4 0.2 0.04 13.3 0.1 2.0 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CEH13397.1 - 0.0095 15.0 0.1 0.02 14.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 CEH13397.1 - 0.0095 15.4 0.0 0.035 13.5 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 CEH13397.1 - 0.0099 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CEH13397.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 CEH13397.1 - 0.014 14.9 0.2 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 CEH13397.1 - 0.016 15.1 0.4 0.034 14.0 0.1 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) PhoH PF02562.11 CEH13397.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 CEH13397.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 CEH13397.1 - 0.023 13.8 0.1 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.1 CEH13397.1 - 0.029 14.7 0.3 5.1 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 CEH13397.1 - 0.052 12.4 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 CEH13397.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 CEH13397.1 - 0.059 12.9 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CEH13397.1 - 0.072 12.7 0.0 0.23 11.1 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 CEH13397.1 - 0.073 12.7 0.0 0.21 11.2 0.0 1.8 1 1 1 2 2 2 0 NACHT domain CPT PF07931.7 CEH13397.1 - 0.078 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 CEH13397.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Ferritin_2 PF13668.1 CEH13398.1 - 7.5e-09 35.6 0.2 7.5e-09 35.6 0.2 2.0 3 0 0 3 3 3 1 Ferritin-like domain DUF1900 PF08954.6 CEH13399.1 - 2.9e-49 166.0 0.0 2.1e-31 108.2 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF1900) WD40 PF00400.27 CEH13399.1 - 3.6e-17 61.5 0.5 0.00037 20.2 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 CEH13399.1 - 0.041 13.5 0.0 26 4.4 0.0 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Spc24 PF08286.6 CEH13400.1 - 0.0011 18.6 4.2 0.044 13.4 0.1 2.6 2 1 0 2 2 2 2 Spc24 subunit of Ndc80 FliJ PF02050.11 CEH13400.1 - 0.1 12.6 4.7 0.13 12.3 2.3 1.8 1 1 0 1 1 1 0 Flagellar FliJ protein APG6 PF04111.7 CEH13400.1 - 0.69 8.8 10.8 5.4 5.9 7.5 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 Fez1 PF06818.10 CEH13400.1 - 1.5 8.8 10.9 0.22 11.5 3.2 2.0 2 0 0 2 2 2 0 Fez1 Phage_GP20 PF06810.6 CEH13400.1 - 2.6 7.4 7.6 0.59 9.5 2.1 2.1 2 1 0 2 2 2 0 Phage minor structural protein GP20 Noelin-1 PF12308.3 CEH13400.1 - 2.7 7.8 4.8 8.7 6.2 0.2 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein IncA PF04156.9 CEH13400.1 - 7.5 6.1 7.8 14 5.2 5.4 1.5 1 1 0 1 1 1 0 IncA protein MutS_V PF00488.16 CEH13402.1 - 1e-73 247.6 0.0 1.6e-73 246.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CEH13402.1 - 7.1e-41 140.2 5.6 1.6e-40 139.1 3.9 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CEH13402.1 - 2.6e-18 66.0 0.0 6.2e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CEH13402.1 - 4.4e-09 36.5 0.0 1.6e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 CEH13402.1 - 0.11 12.7 0.1 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Smr PF01713.16 CEH13403.1 - 1.2e-12 47.8 1.0 2.9e-12 46.6 0.1 2.2 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 CEH13403.1 - 1.7e-06 27.4 0.0 8.6e-06 25.1 0.0 2.2 3 0 0 3 3 3 1 CUE domain DUF1771 PF08590.5 CEH13403.1 - 7.7e-05 22.6 3.0 7.7e-05 22.6 2.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) UBA PF00627.26 CEH13403.1 - 0.0016 18.1 1.5 0.0051 16.6 0.2 2.6 3 0 0 3 3 3 1 UBA/TS-N domain DUF1400 PF07176.6 CEH13403.1 - 0.034 14.0 0.4 0.75 9.7 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) COQ7 PF03232.8 CEH13404.1 - 8.6e-62 207.6 0.0 1.1e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 CEH13404.1 - 0.00036 20.8 0.0 0.00065 20.0 0.0 1.4 1 0 0 1 1 1 1 Rubrerythrin MgtE_N PF03448.12 CEH13404.1 - 0.013 15.7 0.4 0.04 14.2 0.0 1.8 2 0 0 2 2 2 0 MgtE intracellular N domain FliG_N PF14842.1 CEH13404.1 - 0.063 13.3 0.6 1.7 8.7 0.0 2.7 3 0 0 3 3 3 0 FliG N-terminal domain Polysacc_deac_1 PF01522.16 CEH13406.1 - 3.6e-21 75.0 0.1 7.7e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Asparaginase PF00710.15 CEH13407.1 - 2.4e-100 335.4 0.0 2e-77 260.1 0.0 2.4 2 1 1 3 3 3 2 Asparaginase Ank PF00023.25 CEH13407.1 - 1.2e-12 46.9 2.3 5.7e-06 25.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CEH13407.1 - 4.1e-12 46.2 0.0 1.1e-11 44.9 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEH13407.1 - 1.1e-07 31.8 2.0 4.1e-05 23.6 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEH13407.1 - 1.7e-07 31.5 0.3 5.2e-07 29.9 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH13407.1 - 7.1e-07 28.8 0.7 0.011 15.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat FA_hydroxylase PF04116.8 CEH13409.1 - 3.5e-14 53.1 20.3 3.5e-14 53.1 14.0 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily ESSS PF10183.4 CEH13410.1 - 3.9e-20 72.2 0.0 4.5e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FliG_M PF14841.1 CEH13411.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 FliG middle domain TPR_11 PF13414.1 CEH13412.1 - 8.5e-14 50.9 9.8 2.7e-05 23.7 0.2 7.7 8 0 0 8 8 8 3 TPR repeat TPR_19 PF14559.1 CEH13412.1 - 1.2e-11 44.7 9.6 5.9e-05 23.3 0.2 7.0 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEH13412.1 - 7.6e-10 38.6 23.6 0.00092 19.1 1.4 8.8 8 3 1 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CEH13412.1 - 6.7e-08 31.7 0.1 1.7 8.5 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEH13412.1 - 8.1e-07 29.5 26.7 0.00015 22.3 0.1 9.7 8 2 3 12 12 11 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH13412.1 - 3.9e-06 27.0 40.3 0.00027 21.2 0.1 12.4 12 2 2 14 14 12 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEH13412.1 - 5.8e-06 26.0 0.8 0.074 13.2 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEH13412.1 - 6.6e-06 25.6 31.4 0.78 9.8 0.0 10.9 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEH13412.1 - 6.8e-06 25.4 8.0 9.9 5.9 0.0 9.6 11 0 0 11 11 11 0 Tetratricopeptide repeat Apc3 PF12895.2 CEH13412.1 - 6.9e-05 22.9 10.0 0.00072 19.6 0.3 5.6 7 0 0 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CEH13412.1 - 0.00018 21.7 4.3 24 5.6 0.0 7.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Complex1_LYR PF05347.10 CEH13412.1 - 0.00073 19.2 0.0 0.0037 17.0 0.0 2.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) TPR_20 PF14561.1 CEH13412.1 - 0.0011 19.0 2.4 0.019 15.0 0.1 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEH13412.1 - 0.0011 18.8 8.3 0.59 10.1 0.0 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Complex1_LYR_1 PF13232.1 CEH13412.1 - 0.0068 16.5 0.0 0.044 14.0 0.0 2.5 1 0 0 1 1 1 1 Complex1_LYR-like TPR_7 PF13176.1 CEH13412.1 - 0.054 13.3 9.5 8.7 6.4 0.1 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 CEH13412.1 - 0.85 10.2 13.6 2.5 8.8 0.0 6.7 7 0 0 7 7 5 0 Tetratricopeptide repeat RCC1 PF00415.13 CEH13413.1 - 1.9e-53 178.4 19.2 3.5e-10 39.9 0.0 8.5 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CEH13413.1 - 1.7e-29 100.7 31.4 3.1e-07 29.8 0.6 7.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 CEH13413.1 - 0.037 13.4 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Putative carbohydrate binding domain DHquinase_II PF01220.14 CEH13414.1 - 6.1e-57 190.8 0.0 6.9e-57 190.6 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Peripla_BP_1 PF00532.16 CEH13414.1 - 0.015 14.5 0.1 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family PCNA_N PF00705.13 CEH13414.1 - 0.094 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain MCM PF00493.18 CEH13415.1 - 7e-71 238.7 0.3 6.4e-42 143.5 0.0 2.5 2 1 1 3 3 3 2 MCM2/3/5 family MCM_N PF14551.1 CEH13415.1 - 5e-21 75.4 0.0 1.2e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain DUF4449 PF14613.1 CEH13416.1 - 1.2e-10 41.5 0.3 7.4e-10 38.9 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4449) Neugrin PF06413.6 CEH13416.1 - 3.2e-07 30.3 1.1 3.2e-07 30.3 0.7 4.3 4 2 2 6 6 6 1 Neugrin Oligomerisation PF02410.10 CEH13416.1 - 4.9e-07 29.7 0.2 2.4e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Oligomerisation domain MRP-L20 PF12824.2 CEH13416.1 - 0.0014 18.6 6.0 0.0014 18.6 4.1 3.7 2 2 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 FAD_binding_3 PF01494.14 CEH13417.1 - 5.8e-19 68.3 3.0 1.9e-14 53.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 CEH13417.1 - 2.1e-06 26.8 0.0 2.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEH13417.1 - 4e-05 22.6 3.4 0.001 18.0 1.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEH13417.1 - 4.2e-05 23.4 3.4 6.8e-05 22.8 1.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEH13417.1 - 0.0004 20.3 0.2 0.00086 19.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CEH13417.1 - 0.00073 18.2 3.6 0.47 9.0 0.6 3.2 3 0 0 3 3 3 2 Tryptophan halogenase Thi4 PF01946.12 CEH13417.1 - 0.0013 17.9 0.3 0.0023 17.0 0.2 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 CEH13417.1 - 0.0073 15.2 0.1 0.013 14.3 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.11 CEH13417.1 - 0.0082 15.5 0.2 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 CEH13417.1 - 0.022 14.8 0.0 0.068 13.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 CEH13417.1 - 0.023 13.5 0.0 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.22 CEH13417.1 - 0.048 14.0 0.9 0.048 14.0 0.6 3.2 4 0 0 4 4 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEH13417.1 - 0.24 9.8 2.2 0.22 9.9 0.6 1.5 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.19 CEH13417.1 - 0.27 10.2 1.9 0.94 8.4 0.2 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase PXA PF02194.10 CEH13418.1 - 4.8e-17 62.1 1.3 4.8e-17 62.1 0.9 1.7 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 CEH13418.1 - 7.8e-06 25.9 0.0 3.7e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal adh_short PF00106.20 CEH13419.1 - 1.7e-22 80.1 0.3 2.5e-16 60.0 0.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 CEH13419.1 - 2.7e-05 23.9 0.3 0.19 11.3 0.0 2.7 1 1 2 3 3 3 2 KR domain Sld5 PF05916.6 CEH13420.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein Proteasome PF00227.21 CEH13421.1 - 5.1e-45 153.0 3.7 7.7e-43 145.9 0.2 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 CEH13421.1 - 2.5e-15 55.4 0.4 4.2e-15 54.7 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ATP-synt_Eps PF04627.8 CEH13422.1 - 3.1e-19 68.2 0.9 4e-19 67.9 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ribosomal_L23 PF00276.15 CEH13423.1 - 0.00097 19.0 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 DUF572 PF04502.8 CEH13424.1 - 1.6e-62 211.6 20.1 1.9e-61 208.0 13.9 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 CEH13424.1 - 0.012 15.0 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Lar_restr_allev PF14354.1 CEH13424.1 - 0.036 14.3 1.0 0.76 10.1 0.7 2.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar RRN7 PF11781.3 CEH13424.1 - 0.12 11.8 0.6 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-FCS PF06467.9 CEH13424.1 - 0.22 11.2 1.3 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Rubredoxin PF00301.15 CEH13424.1 - 0.54 10.1 4.1 3.9 7.4 2.3 2.7 2 1 0 2 2 2 0 Rubredoxin CDC45 PF02724.9 CEH13425.1 - 4.2e-30 104.3 0.0 4.9e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein CDC45 PF02724.9 CEH13426.1 - 3e-75 253.5 1.0 5.4e-75 252.6 0.7 1.4 1 1 0 1 1 1 1 CDC45-like protein Nitrate_red_del PF02613.10 CEH13426.1 - 0.019 14.7 0.6 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Nitrate reductase delta subunit MiaE_2 PF13794.1 CEH13426.1 - 0.14 11.5 1.7 8.6 5.7 0.1 2.7 2 1 1 3 3 3 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like eIF-1a PF01176.14 CEH13427.1 - 3.9e-28 96.6 0.1 5.5e-28 96.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RRM_6 PF14259.1 CEH13428.1 - 3.4e-08 33.3 0.0 7.3e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEH13428.1 - 6e-07 29.0 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH13428.1 - 0.00053 19.7 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_22 PF03901.12 CEH13432.1 - 2.5e-64 217.8 17.5 3.6e-63 214.0 12.2 2.2 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family SQS_PSY PF00494.14 CEH13433.1 - 8.7e-40 136.6 0.0 1.2e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase UPF0233 PF06781.7 CEH13433.1 - 0.083 12.5 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) ADH_zinc_N_2 PF13602.1 CEH13434.1 - 1.5e-17 64.6 0.0 3.7e-17 63.4 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CEH13434.1 - 8.5e-07 28.5 0.1 3.9e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH13434.1 - 3.7e-05 23.4 0.0 0.00011 21.9 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain CW_binding_2 PF04122.7 CEH13434.1 - 0.017 15.2 0.4 0.032 14.4 0.3 1.3 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Eno-Rase_NADH_b PF12242.3 CEH13434.1 - 0.056 13.2 0.8 0.11 12.2 0.5 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UAA PF08449.6 CEH13435.1 - 1.6e-13 50.3 15.6 2.2e-12 46.5 10.8 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 CEH13435.1 - 1.8e-11 43.8 4.6 1.8e-11 43.8 3.2 2.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CEH13435.1 - 0.015 15.3 3.9 0.015 15.3 2.7 2.4 2 1 0 2 2 2 0 EamA-like transporter family HS1_rep PF02218.10 CEH13435.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Repeat in HS1/Cortactin PHO4 PF01384.15 CEH13435.1 - 0.64 8.6 13.9 0.039 12.6 2.1 2.3 1 1 1 2 2 2 0 Phosphate transporter family MTHFR PF02219.12 CEH13437.1 - 1.2e-107 359.3 0.0 1.7e-107 358.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3479 PF11965.3 CEH13437.1 - 0.051 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) TFIIB PF00382.14 CEH13438.1 - 8.5e-30 102.3 0.1 2.5e-17 62.4 0.0 3.3 2 1 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CEH13438.1 - 1.4e-20 73.3 1.7 1.4e-20 73.3 1.2 4.2 4 1 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 CEH13438.1 - 0.00026 20.2 1.1 0.00057 19.1 0.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 CEH13438.1 - 0.034 13.8 0.9 0.081 12.5 0.6 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Cyclin_N PF00134.18 CEH13438.1 - 0.06 12.9 0.0 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Cyclin, N-terminal domain DZR PF12773.2 CEH13438.1 - 0.12 12.2 0.7 0.28 11.0 0.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.12 CEH13438.1 - 0.26 10.8 1.0 0.46 10.0 0.7 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 zinc_ribbon_2 PF13240.1 CEH13438.1 - 0.29 10.6 1.5 0.69 9.4 1.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Rep_fac-A_C PF08646.5 CEH13439.1 - 2.2e-53 179.8 4.3 2.7e-52 176.3 1.0 2.2 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CEH13439.1 - 1.9e-11 43.6 0.3 6.7e-10 38.6 0.0 3.0 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 CEH13439.1 - 1.4e-06 28.2 1.3 5e-05 23.3 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF223 Rep-A_N PF04057.7 CEH13439.1 - 6.6e-06 25.8 0.3 1.3e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF3999 PF13163.1 CEH13439.1 - 0.0094 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3999) Drc1-Sld2 PF11719.3 CEH13440.1 - 2.7e-10 39.9 17.6 3.5e-08 32.9 12.2 2.7 1 1 0 1 1 1 1 DNA replication and checkpoint protein DUF947 PF06102.7 CEH13442.1 - 6.6e-38 130.1 5.4 6.6e-38 130.1 3.8 2.7 3 1 1 4 4 4 1 Domain of unknown function (DUF947) Urb2 PF10441.4 CEH13443.1 - 3.3e-27 95.5 0.3 3.3e-27 95.5 0.2 4.4 5 0 0 5 5 5 1 Urb2/Npa2 family DUF3677 PF12432.3 CEH13443.1 - 0.01 16.2 0.1 0.041 14.3 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) Pkinase PF00069.20 CEH13444.1 - 1.1e-66 224.6 0.0 1.3e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH13444.1 - 3.7e-32 111.4 0.0 4.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH13444.1 - 5.6e-06 25.5 0.0 7.8e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEH13444.1 - 0.0042 16.8 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CEH13444.1 - 0.0089 14.8 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 MFS_1 PF07690.11 CEH13446.1 - 1.5e-34 119.2 10.7 1.5e-34 119.2 7.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Aminotran_4 PF01063.14 CEH13446.1 - 4.1e-14 52.6 0.0 7.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class IV Sugar_tr PF00083.19 CEH13446.1 - 3.5e-11 42.3 0.7 3.5e-11 42.3 0.5 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 CEH13446.1 - 2.1e-06 26.4 9.8 0.014 13.7 0.2 3.4 3 1 1 4 4 4 3 MFS/sugar transport protein ATG22 PF11700.3 CEH13446.1 - 0.00027 19.5 1.9 0.00027 19.5 1.3 1.8 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like TRI12 PF06609.8 CEH13446.1 - 0.0077 14.4 0.4 0.016 13.4 0.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1295 PF06966.7 CEH13446.1 - 0.036 13.3 0.2 0.073 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) FAD_binding_1 PF00667.15 CEH13447.1 - 6.5e-25 87.8 0.0 9.3e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CEH13447.1 - 2.3e-11 44.2 0.0 5.4e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fib_alpha PF08702.5 CEH13450.1 - 0.019 15.1 2.2 0.025 14.6 1.5 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1875 PF08961.5 CEH13450.1 - 0.072 12.3 0.5 0.078 12.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Seryl_tRNA_N PF02403.17 CEH13450.1 - 0.16 11.9 4.0 0.27 11.2 2.8 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF244 PF03112.9 CEH13450.1 - 0.4 10.1 2.6 0.57 9.7 1.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DUF16 PF01519.11 CEH13450.1 - 1.6 8.9 5.3 3.4 7.9 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 SET PF00856.23 CEH13451.1 - 0.00026 21.3 2.3 0.057 13.7 0.0 3.2 2 1 0 2 2 2 2 SET domain SYS1 PF09801.4 CEH13452.1 - 6e-13 49.0 2.9 1.2e-09 38.2 1.7 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network Cullin PF00888.17 CEH13453.1 - 3e-15 55.7 0.0 7.7e-14 51.1 0.0 2.2 2 1 0 2 2 2 2 Cullin family DUF1771 PF08590.5 CEH13454.1 - 3.7e-09 36.4 3.9 3.7e-09 36.4 2.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 CEH13454.1 - 1.4e-08 34.8 0.1 3.7e-08 33.4 0.1 1.8 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 CEH13454.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 CUE domain zf-CCCH PF00642.19 CEH13454.1 - 0.17 11.6 5.6 1.2 8.8 0.2 2.3 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Asp PF00026.18 CEH13456.1 - 5.7e-42 144.0 1.5 6.8e-42 143.8 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SRF-TF PF00319.13 CEH13457.1 - 1.8e-22 78.2 0.0 3e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Hydantoinase_A PF01968.13 CEH13458.1 - 9.6e-81 271.0 0.0 2.4e-80 269.7 0.0 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CEH13458.1 - 5.9e-57 191.9 1.3 2.7e-56 189.8 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Prenyltrans PF00432.16 CEH13459.1 - 1.1e-30 104.8 2.1 9.3e-10 37.9 0.1 3.5 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CEH13459.1 - 6.3e-15 55.5 2.6 3.8e-07 30.5 0.1 2.8 1 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CEH13459.1 - 4.7e-05 23.3 0.0 0.13 12.3 0.0 2.6 1 1 1 2 2 2 2 Prenyltransferase-like PC-Esterase PF13839.1 CEH13460.1 - 0.00022 21.1 0.0 0.00037 20.3 0.0 1.4 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Nbl1_Borealin_N PF10444.4 CEH13460.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Gal4_dimer PF03902.8 CEH13461.1 - 3.1e-07 30.2 0.7 2.8 7.9 0.0 4.2 4 0 0 4 4 4 3 Gal4-like dimerisation domain IF3_N PF05198.11 CEH13461.1 - 2e-05 24.4 3.2 0.0073 16.2 0.1 3.6 4 0 0 4 4 4 2 Translation initiation factor IF-3, N-terminal domain CheC PF04509.7 CEH13461.1 - 2.2e-05 24.0 5.6 9.4 6.0 0.0 6.1 8 0 0 8 8 8 3 CheC-like family CitT PF12431.3 CEH13461.1 - 0.00028 20.8 1.0 18 5.5 0.0 4.2 4 0 0 4 4 4 0 Transcriptional regulator Cdd1 PF11731.3 CEH13461.1 - 0.0027 17.5 1.6 18 5.3 0.0 3.9 4 0 0 4 4 4 0 Pathogenicity locus DUF3194 PF11419.3 CEH13461.1 - 0.0056 16.8 1.8 33 4.7 0.0 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF3194) FCD PF07729.7 CEH13461.1 - 0.04 14.2 2.0 10 6.4 0.0 3.8 3 1 0 4 4 4 0 FCD domain DUF3774 PF12609.3 CEH13461.1 - 0.053 14.3 0.1 46 4.9 0.0 3.4 3 0 0 3 3 3 0 Wound-induced protein DUF2564 PF10819.3 CEH13461.1 - 0.26 11.4 1.8 4 7.6 0.0 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF2564) ABC2_membrane PF01061.19 CEH13462.1 - 1.7e-58 197.2 49.3 2.2e-31 108.6 10.7 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CEH13462.1 - 1e-36 126.2 0.2 6.9e-17 62.0 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 CEH13462.1 - 3.7e-30 103.6 3.3 1.8e-23 82.1 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CEH13462.1 - 4.5e-13 49.0 0.0 1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 CEH13462.1 - 1.4e-08 34.9 1.5 2.6e-05 24.3 0.4 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 CEH13462.1 - 3.1e-07 29.9 0.1 0.00062 19.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 CEH13462.1 - 5.5e-06 25.6 0.3 4.1e-05 22.8 0.0 2.3 3 0 0 3 3 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 CEH13462.1 - 6.6e-05 23.0 0.0 0.47 10.3 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CEH13462.1 - 0.00011 22.3 0.7 0.06 13.4 0.2 3.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 CEH13462.1 - 0.0015 18.2 0.2 0.15 11.7 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 CEH13462.1 - 0.0017 18.0 0.8 0.76 9.5 0.4 2.8 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 CEH13462.1 - 0.002 17.7 1.1 0.15 11.6 0.2 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 CEH13462.1 - 0.0038 16.6 0.9 0.25 10.7 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CEH13462.1 - 0.0041 16.6 1.3 0.05 13.1 0.1 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 CEH13462.1 - 0.0051 16.0 0.0 0.41 9.8 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CEH13462.1 - 0.0058 17.4 0.0 0.34 11.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 CEH13462.1 - 0.015 15.6 0.0 0.67 10.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 CEH13462.1 - 0.016 15.3 0.2 2.6 8.2 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CEH13462.1 - 0.018 14.8 0.1 0.42 10.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.1 CEH13462.1 - 0.052 13.4 0.0 3.4 7.6 0.0 3.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 CEH13462.1 - 0.064 13.2 0.0 1.3 8.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 CEH13462.1 - 0.085 11.7 0.1 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.20 CEH13462.1 - 0.089 12.2 0.3 9.1 5.7 0.1 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 CEH13462.1 - 0.092 12.4 0.1 10 5.7 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase AAA_23 PF13476.1 CEH13462.1 - 0.11 12.7 0.1 0.37 11.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 CEH13462.1 - 0.12 12.3 3.8 0.37 10.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 CEH13462.1 - 0.18 11.3 1.0 1.4 8.4 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 CEH13462.1 - 0.36 10.3 2.2 20 4.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CEH13462.1 - 0.42 10.0 4.2 13 5.2 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_15 PF13175.1 CEH13462.1 - 0.55 9.2 0.0 4.5 6.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SID-1_RNA_chan PF13965.1 CEH13462.1 - 1.2 7.2 5.7 1.7 6.7 3.3 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 ABC2_membrane_3 PF12698.2 CEH13462.1 - 1.8 7.4 39.5 2.5 7.0 7.1 3.0 2 1 2 4 4 4 0 ABC-2 family transporter protein Thioredoxin PF00085.15 CEH13463.1 - 1.6e-40 136.9 0.0 1.8e-20 72.5 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CEH13463.1 - 4.9e-11 42.7 0.0 0.037 13.8 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CEH13463.1 - 3.4e-08 33.6 1.0 0.0042 17.2 0.1 4.0 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEH13463.1 - 2.2e-06 27.6 0.2 0.008 16.2 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CEH13463.1 - 0.0045 16.9 0.1 0.15 12.0 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CEH13463.1 - 0.0053 16.5 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain DSBA PF01323.15 CEH13463.1 - 0.011 15.3 0.6 3.5 7.1 0.1 2.3 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 CEH13463.1 - 0.015 15.3 1.1 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_9 PF14595.1 CEH13463.1 - 0.028 13.9 0.1 1.4 8.4 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin AhpC-TSA PF00578.16 CEH13463.1 - 0.11 12.2 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AhpC/TSA family zf-U1 PF06220.7 CEH13463.1 - 0.11 12.0 0.2 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger TraF PF13728.1 CEH13463.1 - 0.5 9.8 4.1 9.3 5.6 0.0 3.0 3 0 0 3 3 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.19 CEH13463.1 - 2.1 8.3 4.9 2.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Glutaredoxin Amino_oxidase PF01593.19 CEH13464.1 - 1.4e-15 57.3 0.0 1.4e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CEH13464.1 - 1.2e-12 47.6 0.5 4.1e-12 45.9 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEH13464.1 - 1e-11 44.3 8.9 1.4e-11 43.9 3.2 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CEH13464.1 - 4.6e-08 33.3 0.2 0.0023 18.0 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CEH13464.1 - 2.4e-07 29.9 0.7 3.3e-05 22.9 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CEH13464.1 - 2.9e-06 27.2 0.3 3.6e-05 23.7 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEH13464.1 - 1.6e-05 24.1 0.3 0.0015 17.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CEH13464.1 - 4e-05 22.2 0.5 0.0021 16.6 0.6 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 CEH13464.1 - 7.7e-05 21.9 2.0 0.00068 18.7 1.3 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CEH13464.1 - 0.00011 22.5 4.1 0.0076 16.6 1.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEH13464.1 - 0.0005 19.0 0.9 0.022 13.6 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 CEH13464.1 - 0.00066 18.8 0.3 0.0015 17.7 0.2 1.5 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.11 CEH13464.1 - 0.0015 18.0 2.5 0.0028 17.1 1.7 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 CEH13464.1 - 0.005 16.5 0.7 0.0091 15.7 0.5 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 CEH13464.1 - 0.018 14.8 0.9 0.085 12.6 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 CEH13464.1 - 0.022 14.3 1.4 0.043 13.4 0.9 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.13 CEH13464.1 - 0.03 12.6 0.0 2.6 6.2 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor GMC_oxred_N PF00732.14 CEH13464.1 - 0.037 13.1 0.1 4.7 6.2 0.0 2.4 2 0 0 2 2 2 0 GMC oxidoreductase Shikimate_DH PF01488.15 CEH13464.1 - 0.074 13.1 0.2 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sox_N PF12444.3 CEH13464.1 - 0.18 12.9 0.0 0.35 12.0 0.0 1.5 1 0 0 1 1 1 0 Sox developmental protein N terminal Trp_halogenase PF04820.9 CEH13464.1 - 0.23 10.0 5.4 3.4 6.2 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 CEH13464.1 - 2.3 6.9 5.4 0.92 8.2 1.8 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Bac_rhodopsin PF01036.13 CEH13465.1 - 2.2e-50 171.0 15.8 2.7e-50 170.7 10.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein RPE65 PF03055.10 CEH13466.1 - 1.6e-122 409.5 0.0 1.9e-122 409.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CTD_bind PF04818.8 CEH13467.1 - 0.0033 17.6 0.1 0.32 11.2 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase II-binding domain. TENA_THI-4 PF03070.11 CEH13467.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family HD PF01966.17 CEH13470.1 - 6.7e-05 22.8 0.7 0.00014 21.8 0.5 1.6 1 0 0 1 1 1 1 HD domain HD_4 PF13328.1 CEH13470.1 - 0.034 13.8 0.8 0.084 12.5 0.0 1.9 2 0 0 2 2 2 0 HD domain RCC1_2 PF13540.1 CEH13474.1 - 1.5e-08 34.0 10.7 4.3e-05 23.0 0.1 5.2 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CEH13474.1 - 1.9e-06 27.9 6.4 0.17 12.0 0.0 5.3 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 CEH13474.1 - 3.9e-05 23.2 0.1 0.00011 21.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH13474.1 - 0.13 11.9 0.1 0.35 10.5 0.1 1.8 1 0 0 1 1 1 0 F-box domain Ala_racemase_N PF01168.15 CEH13475.1 - 3.7e-33 114.9 0.0 2.2e-30 105.8 0.0 2.1 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Glyoxalase PF00903.20 CEH13476.1 - 8.2e-19 67.8 0.1 1.1e-18 67.4 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CEH13476.1 - 1.2e-13 51.5 0.0 1.5e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CEH13476.1 - 0.0083 16.1 0.0 0.016 15.2 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 CEH13476.1 - 0.092 12.4 0.1 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 CppA N-terminal adh_short PF00106.20 CEH13477.1 - 3.4e-20 72.6 0.0 9.5e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH13477.1 - 6.3e-06 25.9 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 CEH13477.1 - 0.046 13.8 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CEH13477.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Telomere_reg-2 PF10193.4 CEH13478.1 - 2.6e-28 98.5 0.2 6.6e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 Telomere length regulation protein Ribosomal_L34 PF00468.12 CEH13478.1 - 0.097 12.3 1.6 0.24 11.1 1.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L34 SRP14 PF02290.10 CEH13479.1 - 3.6e-17 62.0 0.0 3.6e-17 62.0 0.0 1.8 2 1 1 3 3 3 1 Signal recognition particle 14kD protein Dsh_C PF12316.3 CEH13479.1 - 1.1 9.2 10.7 2.1 8.4 7.4 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CPSase_L_D2 PF02786.12 CEH13480.1 - 2.8e-111 369.8 0.0 1.1e-81 273.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CEH13480.1 - 6.4e-46 155.0 0.0 1.3e-45 154.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 CEH13480.1 - 3.1e-43 146.8 0.0 5.6e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.23 CEH13480.1 - 4.5e-43 146.9 0.0 1.6e-42 145.1 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 CEH13480.1 - 1.7e-42 144.0 0.1 7.9e-21 74.2 0.0 3.4 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 CEH13480.1 - 2.2e-39 134.0 0.0 4.4e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 CEH13480.1 - 2.6e-35 121.6 0.0 5e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 CEH13480.1 - 9.1e-34 116.7 0.6 6.9e-20 71.5 0.0 3.2 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CEH13480.1 - 1.2e-22 80.1 0.0 8e-13 47.8 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CEH13480.1 - 9.2e-16 57.6 0.0 4.5e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CEH13480.1 - 1.6e-14 53.8 0.0 4.6e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 CEH13480.1 - 1.1e-10 41.3 0.0 5.8e-10 38.9 0.0 2.4 1 0 0 1 1 1 1 MGS-like domain Peptidase_C26 PF07722.8 CEH13480.1 - 1.8e-06 27.5 0.1 5.7e-05 22.6 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 CEH13480.1 - 1.9e-05 24.5 0.0 0.16 11.8 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain TrkA_N PF02254.13 CEH13480.1 - 0.031 14.2 0.0 0.93 9.5 0.0 3.2 3 0 0 3 3 3 0 TrkA-N domain RimK PF08443.6 CEH13480.1 - 0.079 12.4 0.0 6.5 6.1 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain UPF0172 PF03665.8 CEH13481.1 - 5.2e-32 110.9 0.0 6.3e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) plasmid_Toxin PF12703.2 CEH13481.1 - 0.079 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system WES_acyltransf PF03007.11 CEH13482.1 - 7.8e-09 35.4 0.8 2.2e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Cyt-b5 PF00173.23 CEH13483.1 - 1e-22 79.6 0.0 1.1e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CHORD PF04968.7 CEH13484.1 - 2.8e-23 81.9 4.7 2.8e-23 81.9 3.3 1.8 2 0 0 2 2 2 1 CHORD CS PF04969.11 CEH13484.1 - 9.2e-06 26.1 0.1 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 CS domain Mito_carr PF00153.22 CEH13485.1 - 2.5e-14 52.7 0.2 3.1e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.22 CEH13486.1 - 1.8e-16 59.6 0.0 3.1e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein DUF3446 PF11928.3 CEH13486.1 - 10 6.4 17.0 17 5.7 11.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Methyltransf_6 PF03737.10 CEH13487.1 - 1.4e-24 86.6 0.1 6.5e-24 84.5 0.1 1.8 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase HECT PF00632.20 CEH13488.1 - 3.8e-74 249.7 0.0 5.2e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RIX1 PF08167.7 CEH13488.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis DUF973 PF06157.6 CEH13488.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3385 PF11865.3 CEH13488.1 - 2 8.3 2.6 9.1 6.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) LtrA PF06772.6 CEH13489.1 - 1e-19 70.6 10.9 1.5e-19 70.1 7.5 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) zf-C2H2_4 PF13894.1 CEH13492.1 - 3.5e-08 33.2 4.7 0.0067 16.6 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEH13492.1 - 3.1e-07 30.3 9.2 0.0013 18.9 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEH13492.1 - 0.024 14.9 0.5 0.024 14.9 0.3 2.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CEH13492.1 - 1.2 9.4 2.8 14 6.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Herpes_LMP1 PF05297.6 CEH13492.1 - 4.2 6.2 5.1 7.1 5.4 3.5 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2419 PF10343.4 CEH13493.1 - 0.005 16.1 0.0 0.014 14.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2419) DUF1860 PF08949.5 CEH13493.1 - 0.073 12.6 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) Glycos_transf_2 PF00535.21 CEH13494.1 - 2.5e-30 105.3 0.0 3.3e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CEH13494.1 - 1.2e-14 54.6 0.0 1.6e-14 54.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CEH13494.1 - 1.7e-07 30.6 0.0 2.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CEH13494.1 - 0.00052 19.3 0.0 0.00085 18.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 CEH13494.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Ank_4 PF13637.1 CEH13495.1 - 2.7e-17 62.7 0.8 1.2e-09 38.3 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CEH13495.1 - 1.3e-12 47.8 0.0 2.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CEH13495.1 - 2.2e-12 46.1 0.1 5.1e-07 29.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CEH13495.1 - 2.7e-12 46.5 0.6 9.5e-07 28.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH13495.1 - 1.3e-11 43.5 0.3 2.1e-05 24.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Methyltransf_18 PF12847.2 CEH13495.1 - 0.0038 17.7 0.0 0.014 15.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.1 CEH13495.1 - 0.038 14.8 0.0 0.14 13.0 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CEH13495.1 - 0.098 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Acetyltransf_1 PF00583.19 CEH13497.1 - 5.3e-11 42.3 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CEH13497.1 - 8.7e-07 28.6 0.0 2.6e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 CEH13497.1 - 3.1e-06 27.2 0.1 4.5e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CEH13497.1 - 1.1e-05 25.4 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEH13497.1 - 0.0017 18.4 0.3 0.0048 17.0 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEH13497.1 - 0.022 14.6 0.4 0.071 12.9 0.1 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CEH13497.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PfkB PF00294.19 CEH13498.1 - 8.1e-40 136.8 0.0 9.4e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Indigoidine_A PF04227.7 CEH13499.1 - 2e-108 362.0 0.8 3.9e-108 361.1 0.6 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 CEH13499.1 - 2.1e-16 59.9 0.0 1.6e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DAO PF01266.19 CEH13500.1 - 1e-19 70.7 0.0 4e-16 58.8 0.0 3.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase OPA3 PF07047.7 CEH13502.1 - 5.4e-32 110.3 1.0 1e-31 109.4 0.7 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Phage_capsid PF05065.8 CEH13502.1 - 0.13 11.4 0.5 0.27 10.3 0.3 1.5 1 0 0 1 1 1 0 Phage capsid family Peptidase_C48 PF02902.14 CEH13504.1 - 1.6e-27 96.5 1.3 2.9e-11 43.4 0.1 3.3 2 1 1 3 3 3 3 Ulp1 protease family, C-terminal catalytic domain Alk_phosphatase PF00245.15 CEH13505.1 - 6.1e-75 252.5 0.0 1.3e-39 136.0 0.0 2.5 2 1 0 2 2 2 2 Alkaline phosphatase CDP-OH_P_transf PF01066.16 CEH13506.1 - 6.3e-12 45.6 1.8 6.3e-12 45.6 1.3 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Thioredoxin_8 PF13905.1 CEH13507.1 - 8.3e-10 38.6 0.1 5.1e-08 32.9 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like Fork_head_N PF08430.7 CEH13507.1 - 0.02 15.2 5.6 0.037 14.4 3.9 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region Redoxin PF08534.5 CEH13507.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Redoxin Septin PF00735.13 CEH13508.1 - 1.9e-114 381.4 0.2 2.6e-114 381.0 0.2 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CEH13508.1 - 9e-09 35.3 0.0 2.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEH13508.1 - 4.5e-07 29.4 0.6 3.8e-06 26.4 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CEH13508.1 - 6.7e-07 28.6 0.5 1.9e-06 27.1 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 CEH13508.1 - 3.8e-05 23.1 0.8 0.00012 21.5 0.4 2.0 2 1 0 2 2 2 1 Ras family Miro PF08477.8 CEH13508.1 - 0.0004 20.8 0.2 0.0017 18.8 0.2 2.1 1 1 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 CEH13508.1 - 0.00041 20.4 0.7 0.0039 17.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 CEH13508.1 - 0.00043 19.8 0.0 0.00051 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_24 PF13479.1 CEH13508.1 - 0.00045 19.8 0.0 0.00091 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 CEH13508.1 - 0.00053 19.1 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.1 CEH13508.1 - 0.00057 19.9 0.4 0.0059 16.6 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 CEH13508.1 - 0.0013 18.9 0.1 0.0041 17.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.4 CEH13508.1 - 0.002 17.6 1.4 0.082 12.3 0.1 2.6 2 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CEH13508.1 - 0.0029 17.3 0.1 0.0068 16.1 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 CEH13508.1 - 0.0056 15.8 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 CEH13508.1 - 0.0081 15.7 1.5 2.3 7.7 0.1 2.6 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 CEH13508.1 - 0.011 15.6 5.4 0.37 10.5 0.2 2.7 2 1 1 3 3 3 0 Dynamin family NACHT PF05729.7 CEH13508.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 CEH13508.1 - 0.02 14.0 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CEH13508.1 - 0.021 14.3 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TraK PF06586.6 CEH13508.1 - 0.024 13.7 0.1 0.26 10.4 0.0 2.1 2 0 0 2 2 2 0 TraK protein FeoB_N PF02421.13 CEH13508.1 - 0.026 13.8 0.2 0.074 12.3 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.1 CEH13508.1 - 0.044 13.6 0.4 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CEH13508.1 - 0.049 13.5 0.6 0.12 12.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 CEH13508.1 - 0.056 13.0 3.2 5.5 6.5 0.2 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein Sigma54_activat PF00158.21 CEH13508.1 - 0.057 12.9 0.1 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 CEH13508.1 - 0.061 13.6 1.0 0.11 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CEH13508.1 - 0.08 12.4 0.2 0.08 12.4 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 CEH13508.1 - 0.085 13.0 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 CEH13508.1 - 0.098 11.9 0.1 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein cobW PF02492.14 CEH13508.1 - 0.12 11.8 0.1 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 CEH13508.1 - 6 7.1 11.5 80 3.4 8.0 2.1 1 1 0 1 1 1 0 AAA domain zf-CSL PF05207.8 CEH13509.1 - 9.6e-25 85.8 0.8 1.4e-24 85.3 0.6 1.2 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 CEH13509.1 - 0.012 15.1 0.4 0.019 14.5 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CEH13509.1 - 0.034 13.8 0.6 0.052 13.2 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.1 CEH13509.1 - 0.038 13.5 0.4 0.07 12.7 0.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 CEH13509.1 - 0.04 13.8 0.3 0.068 13.1 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain LIP PF03583.9 CEH13511.1 - 8.5e-57 192.5 0.2 1.4e-56 191.8 0.1 1.2 1 0 0 1 1 1 1 Secretory lipase PAS_9 PF13426.1 CEH13511.1 - 4.3e-20 72.0 0.0 3.1e-19 69.2 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 CEH13511.1 - 7.7e-07 29.1 0.0 1.3e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold RGS PF00615.14 CEH13511.1 - 1.8e-06 28.0 0.3 3.4e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS PF00989.19 CEH13511.1 - 3.9e-05 23.4 0.0 0.00017 21.3 0.0 2.0 2 0 0 2 2 2 1 PAS fold Prp19 PF08606.6 CEH13511.1 - 0.051 13.3 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like PAS_3 PF08447.6 CEH13511.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold 4HBT PF03061.17 CEH13512.1 - 1.8e-10 40.8 0.1 2.7e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 CEH13512.1 - 7.9e-05 22.5 0.3 0.00023 20.9 0.2 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily ZZ PF00569.12 CEH13515.1 - 1.2e-07 31.0 29.5 2.1e-06 27.1 0.5 3.6 3 1 0 3 3 3 3 Zinc finger, ZZ type PB1 PF00564.19 CEH13515.1 - 4.2e-06 26.3 0.1 8.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 PB1 domain cobW PF02492.14 CEH13516.1 - 2.8e-33 114.8 0.0 3.5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CEH13516.1 - 0.0001 21.2 0.4 0.0013 17.5 0.3 2.0 1 1 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 CEH13516.1 - 0.0086 16.3 0.0 0.014 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEH13516.1 - 0.012 16.3 0.1 0.017 15.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEH13516.1 - 0.062 13.2 0.1 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CEH13516.1 - 0.084 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 CEH13516.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.7 CEH13516.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.7 CEH13516.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Anoctamin PF04547.7 CEH13517.1 - 1.3e-96 324.0 0.1 1.6e-96 323.6 0.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel UAA PF08449.6 CEH13518.1 - 7.6e-70 235.2 13.7 2.5e-54 184.2 5.4 2.1 2 0 0 2 2 2 2 UAA transporter family EmrE PF13536.1 CEH13518.1 - 0.0019 18.3 4.0 0.0019 18.3 2.8 4.2 3 3 1 5 5 5 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CEH13518.1 - 0.0033 16.5 3.0 0.0033 16.5 2.1 2.0 1 1 1 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 CEH13518.1 - 0.29 10.7 12.7 0.12 12.0 0.7 3.0 3 0 0 3 3 3 0 Triose-phosphate Transporter family dsDNA_bind PF01984.15 CEH13519.1 - 5.2e-22 77.8 0.1 6.2e-22 77.6 0.1 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain FMN_dh PF01070.13 CEH13520.1 - 2.8e-120 401.4 0.0 3.5e-120 401.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CEH13520.1 - 3.6e-23 81.1 0.1 1e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CEH13520.1 - 0.00067 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CEH13520.1 - 0.0012 17.8 0.1 0.0029 16.5 0.1 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 CEH13520.1 - 0.017 14.1 0.0 4 6.4 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ribosomal_S11 PF00411.14 CEH13520.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S11 DHO_dh PF01180.16 CEH13520.1 - 0.14 11.1 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase FAD_binding_4 PF01565.18 CEH13521.1 - 5.2e-19 68.1 1.0 5.2e-19 68.1 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 CEH13521.1 - 4.8e-11 42.3 0.2 1.3e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like MelC1 PF06236.6 CEH13521.1 - 0.0064 16.4 0.1 0.016 15.1 0.1 1.6 1 0 0 1 1 1 1 Tyrosinase co-factor MelC1 SET PF00856.23 CEH13522.1 - 9.1e-05 22.8 0.0 0.00026 21.3 0.0 1.8 1 1 0 1 1 1 1 SET domain Hexapep PF00132.19 CEH13525.1 - 1.3e-08 33.9 12.7 0.001 18.4 0.9 4.3 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) WD40 PF00400.27 CEH13526.1 - 2.6e-18 65.1 4.3 1.1e-05 25.1 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat AF-4 PF05110.8 CEH13530.1 - 0.57 7.9 5.9 0.82 7.4 4.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CTP_transf_1 PF01148.15 CEH13531.1 - 9.3e-11 41.8 3.4 2.6e-09 37.1 0.3 2.4 1 1 1 2 2 2 2 Cytidylyltransferase family LisH PF08513.6 CEH13532.1 - 0.00027 20.5 0.4 0.00047 19.8 0.3 1.4 1 0 0 1 1 1 1 LisH DUF1713 PF08213.6 CEH13535.1 - 2.6e-10 39.7 22.7 7.2e-10 38.3 15.8 1.8 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pkinase PF00069.20 CEH13536.1 - 3.9e-58 196.6 0.1 5.7e-58 196.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH13536.1 - 3.2e-20 72.3 0.1 6e-20 71.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Proteasome PF00227.21 CEH13537.1 - 1.1e-59 200.8 0.2 1.4e-59 200.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEH13537.1 - 3.3e-15 55.0 0.3 6.5e-15 54.1 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NPCBM PF08305.6 CEH13537.1 - 0.0076 16.2 0.5 0.53 10.2 0.0 2.2 2 0 0 2 2 2 2 NPCBM/NEW2 domain Aminotran_1_2 PF00155.16 CEH13538.1 - 1.8e-83 280.5 0.0 2e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_6 PF12697.2 CEH13540.1 - 9.3e-05 22.4 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CEH13540.1 - 0.00091 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 CEH13540.1 - 0.0024 17.6 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CEH13540.1 - 0.0025 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF3089 PF11288.3 CEH13540.1 - 0.0081 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) PE-PPE PF08237.6 CEH13540.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain PGAP1 PF07819.8 CEH13540.1 - 0.064 12.8 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 CEH13540.1 - 0.094 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MgtE PF01769.11 CEH13541.1 - 5.9e-23 81.6 31.6 3.1e-08 33.9 0.3 5.0 5 0 0 5 5 5 4 Divalent cation transporter Myelin-PO_C PF10570.4 CEH13541.1 - 0.068 13.2 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Myelin-PO cytoplasmic C-term p65 binding region PufQ PF05398.6 CEH13541.1 - 7.6 6.6 6.4 0.83 9.7 0.0 2.7 2 1 1 3 3 3 0 PufQ cytochrome subunit Amidohydro_4 PF13147.1 CEH13542.1 - 8.9e-17 62.0 3.6 8.9e-17 62.0 2.5 2.6 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 CEH13542.1 - 3.2e-13 49.2 0.3 7.1e-11 41.7 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 CEH13542.1 - 1.8e-12 47.5 0.2 1.5e-08 34.6 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 CEH13542.1 - 1.9e-07 30.6 1.0 2.9e-06 26.7 0.0 2.8 3 0 0 3 3 3 1 Amidohydrolase family CHCH PF06747.8 CEH13546.1 - 0.00021 21.0 4.6 0.0004 20.2 3.2 1.5 1 0 0 1 1 1 1 CHCH domain SR-25 PF10500.4 CEH13546.1 - 9.3 5.6 9.7 21 4.5 0.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Na_Ca_ex PF01699.19 CEH13548.1 - 1e-39 135.3 22.0 4.6e-21 74.8 3.9 2.7 2 1 0 2 2 2 2 Sodium/calcium exchanger protein ATP-synt_8 PF00895.15 CEH13548.1 - 0.33 11.1 3.2 1.9 8.7 0.0 2.9 2 0 0 2 2 2 0 ATP synthase protein 8 BAR_2 PF10455.4 CEH13549.1 - 5.1e-43 147.0 0.0 1.1e-42 145.9 0.0 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 CEH13549.1 - 2.1e-17 63.4 1.2 5.7e-14 52.1 0.4 2.1 2 0 0 2 2 2 2 BAR domain Uds1 PF15456.1 CEH13549.1 - 0.068 13.1 6.4 0.099 12.6 0.0 2.6 2 1 0 2 2 2 0 Up-regulated During Septation Phasin_2 PF09361.5 CEH13549.1 - 0.076 13.0 7.4 0.28 11.2 5.2 2.0 1 0 0 1 1 1 0 Phasin protein Telethonin PF09470.5 CEH13549.1 - 0.084 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Telethonin protein Spectrin PF00435.16 CEH13549.1 - 0.086 13.1 5.9 0.13 12.5 0.1 2.8 2 1 0 2 2 2 0 Spectrin repeat DUF16 PF01519.11 CEH13549.1 - 0.089 13.0 0.6 0.36 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Seryl_tRNA_N PF02403.17 CEH13549.1 - 0.26 11.3 4.0 0.7 9.9 0.0 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HSCB_C PF07743.8 CEH13549.1 - 7.3 7.1 9.1 7.5 7.0 3.1 2.9 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain WGG PF10273.4 CEH13550.1 - 1.2e-18 66.9 0.0 2e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Glyco_transf_17 PF04724.8 CEH13551.1 - 2.5e-91 306.3 0.0 2.9e-91 306.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 RNase_H PF00075.19 CEH13552.1 - 5.2e-18 65.6 0.0 1.1e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 CEH13552.1 - 0.00034 20.3 0.3 0.00093 18.9 0.2 1.8 1 1 0 1 1 1 1 Reverse transcriptase-like Acetyltransf_7 PF13508.1 CEH13554.1 - 0.00017 21.6 0.0 0.00056 20.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEH13554.1 - 0.0011 18.9 0.0 0.0028 17.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CEH13554.1 - 0.049 13.4 0.1 0.18 11.6 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEH13554.1 - 0.098 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Phos_pyr_kin PF08543.7 CEH13555.1 - 3.1e-07 29.8 0.0 6.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CEH13555.1 - 6.5e-07 28.7 0.0 2.1e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase ubiquitin PF00240.18 CEH13556.1 - 2.2e-25 87.8 0.0 2.5e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CEH13556.1 - 1.7e-15 56.4 0.0 1.9e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEH13556.1 - 0.00025 21.2 0.0 0.00064 19.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain GST_C_3 PF14497.1 CEH13558.1 - 2.2e-08 34.4 0.0 3.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEH13558.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEH13558.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CEH13558.1 - 0.11 12.7 0.0 1 9.6 0.0 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Zn_clus PF00172.13 CEH13560.1 - 1.3e-05 24.9 10.4 2e-05 24.4 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 CEH13562.1 - 1.6e-21 75.3 0.3 1.9e-06 27.5 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CEH13562.1 - 0.32 9.7 0.0 49 2.5 0.0 3.1 3 0 0 3 3 3 0 Coatomer WD associated region CIA30 PF08547.7 CEH13563.1 - 1.9e-18 66.8 0.0 2.6e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) ubiquitin PF00240.18 CEH13565.1 - 2e-69 228.9 6.6 3.1e-34 116.1 0.5 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CEH13565.1 - 1.6e-39 133.4 6.4 3.4e-19 68.3 0.5 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEH13565.1 - 1.5e-12 47.5 1.5 0.0001 22.4 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain zf-AN1 PF01428.11 CEH13565.1 - 2.3e-10 40.1 3.9 4.1e-10 39.3 2.7 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Telomere_Sde2 PF13019.1 CEH13565.1 - 2.5e-10 40.3 0.0 0.00059 19.5 0.0 2.3 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CEH13565.1 - 5.6e-07 29.4 0.2 0.041 13.7 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CEH13565.1 - 1.6e-06 28.2 0.2 0.042 14.0 0.0 2.3 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CEH13565.1 - 7.5e-05 22.7 0.0 0.54 10.3 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 CEH13565.1 - 0.0017 18.0 0.5 2.3 8.0 0.0 2.3 2 0 0 2 2 2 2 FlgD Ig-like domain TUG-UBL1 PF11470.3 CEH13565.1 - 0.0046 16.8 0.4 3.9 7.4 0.0 2.5 2 0 0 2 2 2 2 GLUT4 regulating protein TUG Plexin_cytopl PF08337.7 CEH13565.1 - 0.0076 14.6 2.4 2.5 6.2 0.2 3.3 3 1 0 3 3 3 1 Plexin cytoplasmic RasGAP domain Methyltrans_RNA PF04452.9 CEH13565.1 - 0.036 13.1 0.1 0.65 9.0 0.0 2.3 2 0 0 2 2 2 0 RNA methyltransferase Tash_PEST PF07708.6 CEH13565.1 - 0.16 11.9 10.5 2.5 8.1 1.2 2.5 2 0 0 2 2 2 0 Tash protein PEST motif FERM_N PF09379.5 CEH13565.1 - 0.2 11.7 2.4 55 3.9 0.1 3.9 3 2 0 3 3 3 0 FERM N-terminal domain IBR PF01485.16 CEH13565.1 - 0.47 10.3 4.8 0.85 9.5 3.4 1.3 1 0 0 1 1 1 0 IBR domain DUF2207 PF09972.4 CEH13565.1 - 0.52 8.8 3.2 8.1 4.9 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) F-box-like PF12937.2 CEH13566.1 - 1.2e-06 28.1 0.6 0.0039 16.8 0.2 3.0 2 0 0 2 2 2 2 F-box-like DNA_pol_B_palm PF14792.1 CEH13567.1 - 5.4e-18 65.0 0.0 1.3e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 CEH13567.1 - 7.2e-18 64.0 0.0 1.3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 CEH13567.1 - 4.1e-11 42.9 0.5 1.4e-10 41.1 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 CEH13567.1 - 0.00019 20.9 0.0 0.00052 19.5 0.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 CEH13567.1 - 0.00075 19.7 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.1 CEH13567.1 - 0.0045 17.1 0.2 0.21 11.7 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain BRCT PF00533.21 CEH13567.1 - 0.02 15.0 0.0 0.41 10.8 0.0 2.9 2 2 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Sec2p PF06428.6 CEH13571.1 - 7.6e-05 22.4 6.8 7.6e-05 22.4 4.7 2.7 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p FA_hydroxylase PF04116.8 CEH13572.1 - 4.5e-10 39.9 10.2 4.5e-10 39.9 7.1 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ammonium_transp PF00909.16 CEH13574.1 - 1.1e-110 369.9 28.4 1.2e-110 369.7 19.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TMEM107 PF14995.1 CEH13574.1 - 0.015 15.4 3.7 1.1 9.4 0.8 2.7 2 0 0 2 2 2 0 Transmembrane protein Pkinase PF00069.20 CEH13575.1 - 6e-60 202.5 0.0 7.1e-57 192.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH13575.1 - 1.5e-27 96.3 0.1 1.7e-26 92.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH13575.1 - 0.00084 19.1 0.3 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CEH13575.1 - 0.13 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CAF-1_p150 PF11600.3 CEH13577.1 - 0.00079 18.8 24.1 0.0011 18.3 16.7 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF809 PF05663.6 CEH13577.1 - 0.65 9.9 3.9 1.1 9.1 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) G-patch PF01585.18 CEH13577.1 - 9.2 6.1 9.0 1.7 8.5 2.5 2.3 2 0 0 2 2 2 0 G-patch domain Glutaredoxin PF00462.19 CEH13578.1 - 1e-21 76.6 0.0 1.3e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CEH13578.1 - 2.2e-05 24.1 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain GST_N_3 PF13417.1 CEH13578.1 - 0.00026 21.1 0.0 0.00031 20.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DSBA PF01323.15 CEH13578.1 - 0.0011 18.6 0.6 0.069 12.7 0.1 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 CEH13578.1 - 0.0013 18.9 0.1 0.0059 16.7 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 CEH13578.1 - 0.0076 16.2 0.1 2.5 8.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin DUF836 PF05768.9 CEH13578.1 - 0.011 15.9 0.0 0.015 15.5 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.1 CEH13578.1 - 0.025 14.5 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 CEH13578.1 - 0.079 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin UQ_con PF00179.21 CEH13579.1 - 2.3e-38 130.7 0.0 3.2e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 CEH13579.1 - 4.3e-16 58.2 0.5 7.7e-16 57.4 0.3 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 CEH13579.1 - 2.7e-05 23.9 0.0 4.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B FeoA PF04023.9 CEH13579.1 - 0.0053 16.7 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 FeoA domain Aminotran_1_2 PF00155.16 CEH13580.1 - 4e-34 118.1 0.0 5e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEH13580.1 - 0.044 12.9 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Glyco_hydro_31 PF01055.21 CEH13581.1 - 7.5e-123 410.6 1.8 1e-122 410.1 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Phage_int_SAM_4 PF13495.1 CEH13581.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF4368 PF14287.1 CEH13581.1 - 0.092 12.5 0.1 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) Fungal_trans PF04082.13 CEH13583.1 - 1.6e-25 89.4 0.0 2.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH13583.1 - 2.4e-09 36.9 1.9 2.4e-09 36.9 1.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Caleosin PF05042.8 CEH13584.1 - 1.2e-46 158.4 0.0 1.5e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein CLASP_N PF12348.3 CEH13585.1 - 1.9e-70 236.7 0.0 1.2e-59 201.3 0.0 3.2 2 1 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 CEH13585.1 - 9.2e-06 25.3 3.5 5.5 7.3 0.1 6.4 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 CEH13585.1 - 0.00046 20.4 19.1 0.034 14.4 0.0 5.6 3 2 1 4 4 4 2 HEAT repeats DUF3361 PF11841.3 CEH13585.1 - 0.12 12.0 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) HEAT_EZ PF13513.1 CEH13585.1 - 4.7 7.8 14.4 0.8 10.2 0.2 5.3 5 1 1 6 6 6 0 HEAT-like repeat DUF962 PF06127.6 CEH13586.1 - 1.7e-23 82.3 0.0 2.6e-23 81.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF962) VMA21 PF09446.5 CEH13586.1 - 0.047 13.6 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 VMA21-like domain SH3_9 PF14604.1 CEH13588.1 - 7.1e-26 89.5 3.8 2.7e-16 58.8 0.1 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 CEH13588.1 - 1.4e-19 69.1 4.6 1.3e-14 53.3 0.1 3.0 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.12 CEH13588.1 - 2e-16 59.1 0.4 1.1e-09 37.6 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 CEH13588.1 - 6.8e-16 58.2 0.0 1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein UPF0164 PF03687.8 CEH13588.1 - 0.071 11.6 0.4 0.11 10.9 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) NfeD PF01957.13 CEH13589.1 - 0.25 11.4 3.5 0.64 10.1 2.5 1.8 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding PXA PF02194.10 CEH13590.1 - 0.0071 15.9 0.9 0.018 14.6 0.6 1.7 1 0 0 1 1 1 1 PXA domain Pkinase PF00069.20 CEH13590.1 - 0.044 12.9 0.1 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain ABC2_membrane PF01061.19 CEH13591.1 - 7e-77 257.3 64.8 1.2e-42 145.4 20.7 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CEH13591.1 - 3.4e-36 124.5 0.0 1.8e-18 67.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CEH13591.1 - 2.7e-21 75.1 2.0 4.5e-19 68.0 0.1 2.9 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 CEH13591.1 - 3.2e-09 36.2 47.0 2e-07 30.3 10.0 3.6 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_29 PF13555.1 CEH13591.1 - 8.4e-05 22.0 0.9 0.0087 15.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CEH13591.1 - 0.0003 20.2 0.1 0.0023 17.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 CEH13591.1 - 0.00038 20.5 0.0 0.076 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CEH13591.1 - 0.00049 20.0 0.0 0.64 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CEH13591.1 - 0.00053 19.2 0.1 0.0021 17.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 CEH13591.1 - 0.0032 17.1 0.0 0.36 10.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 CEH13591.1 - 0.0035 17.4 1.0 0.29 11.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEH13591.1 - 0.0039 17.1 0.5 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CEH13591.1 - 0.0054 17.0 0.1 0.22 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CEH13591.1 - 0.0063 16.4 0.4 0.026 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CEH13591.1 - 0.0083 15.5 0.3 0.17 11.2 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 CEH13591.1 - 0.011 16.6 0.0 0.3 11.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CEH13591.1 - 0.04 13.3 0.1 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family SMC_N PF02463.14 CEH13591.1 - 0.048 12.8 0.0 0.26 10.4 0.0 2.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CEH13591.1 - 0.064 12.6 0.2 5.2 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 CEH13591.1 - 0.077 12.9 0.0 0.83 9.6 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CEH13591.1 - 0.1 12.7 0.0 23 5.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 CEH13591.1 - 0.14 12.1 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 CEH13591.1 - 0.14 11.9 0.9 2.7 7.8 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 CEH13591.1 - 0.19 12.0 0.1 0.78 10.0 0.1 2.0 1 0 0 1 1 1 0 AAA domain Aha1_N PF09229.6 CEH13593.1 - 9.7e-25 86.9 0.0 1.4e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Glyco_hydro_16 PF00722.16 CEH13594.1 - 2.5e-07 30.1 0.0 7.9e-07 28.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Homoserine_dh PF00742.14 CEH13595.1 - 6.9e-46 156.1 0.0 1e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CEH13595.1 - 4.7e-13 49.5 0.0 1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CEH13595.1 - 0.0059 16.8 0.1 0.026 14.8 0.1 2.0 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF566 PF04484.7 CEH13596.1 - 0.064 12.7 9.3 0.14 11.6 6.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF566) zf-DHHC PF01529.15 CEH13598.1 - 2e-05 24.0 0.0 6e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Mt_ATP-synt_B PF05405.9 CEH13599.1 - 4.6e-45 153.0 6.1 5.3e-45 152.7 4.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Virulence_fact PF13769.1 CEH13599.1 - 0.042 13.7 1.9 0.086 12.7 1.3 1.6 1 0 0 1 1 1 0 Virulence factor PBP_sp32 PF07222.7 CEH13599.1 - 0.38 9.8 5.4 0.51 9.4 3.8 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Glyco_hydro_43 PF04616.9 CEH13600.1 - 5.8e-21 74.8 7.3 1e-08 34.6 1.1 3.7 4 1 0 4 4 4 3 Glycosyl hydrolases family 43 Glyco_hydro_18 PF00704.23 CEH13602.1 - 1.4e-62 212.1 3.1 2.2e-62 211.5 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DNA_pol_viral_N PF00242.12 CEH13602.1 - 0.43 9.5 12.4 0.65 8.9 8.6 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RAP1 PF07218.6 CEH13602.1 - 7.1 4.5 10.8 9.8 4.1 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 CEH13602.1 - 7.7 4.6 14.7 11 4.1 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Glyco_hydro_38 PF01074.17 CEH13603.1 - 3.5e-77 259.3 0.1 5e-77 258.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CEH13603.1 - 2.9e-50 171.4 0.1 6e-50 170.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CEH13603.1 - 4.7e-22 78.0 0.1 8.8e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_57 PF03065.10 CEH13603.1 - 0.0031 16.4 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 7TMR-DISMED2 PF07696.6 CEH13603.1 - 0.018 14.4 0.5 0.044 13.2 0.3 1.6 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 Carbpep_Y_N PF05388.6 CEH13603.1 - 0.044 13.9 0.0 0.45 10.6 0.0 2.7 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide RCR PF12273.3 CEH13605.1 - 0.012 16.1 0.4 0.039 14.5 0.0 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.11 CEH13605.1 - 0.054 11.7 0.0 0.078 11.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NS3_envE PF02723.9 CEH13605.1 - 0.66 9.9 2.4 1.5 8.7 1.7 1.5 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E FeoB_N PF02421.13 CEH13607.1 - 0.014 14.6 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B Kp4 PF09044.5 CEH13607.1 - 0.018 14.8 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Kp4 DNA_alkylation PF08713.6 CEH13607.1 - 0.057 12.9 0.1 0.062 12.8 0.1 1.1 1 0 0 1 1 1 0 DNA alkylation repair enzyme DnaJ PF00226.26 CEH13608.1 - 2.7e-16 59.0 0.8 5.6e-16 58.0 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain PNK3P PF08645.6 CEH13609.1 - 1.8e-43 147.7 0.0 3.7e-41 140.2 0.0 2.2 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 CEH13609.1 - 2.6e-25 88.9 0.1 9.2e-25 87.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEH13609.1 - 2.3e-05 23.6 0.0 0.0043 16.1 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin KTI12 PF08433.5 CEH13609.1 - 0.0077 15.4 1.1 0.62 9.2 0.8 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CEH13609.1 - 0.036 14.9 0.0 0.1 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CEH13609.1 - 0.16 12.3 0.0 23 5.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain Nucleoplasmin PF03066.10 CEH13610.1 - 0.034 13.6 1.4 0.073 12.5 1.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CEH13610.1 - 0.066 13.4 3.5 0.15 12.2 2.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 CEH13610.1 - 0.49 10.7 4.8 1.2 9.4 3.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 CEH13610.1 - 2 7.5 4.4 3.7 6.7 3.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.1 CEH13610.1 - 6.2 7.0 12.0 5.9 7.1 4.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Spt5_N PF11942.3 CEH13610.1 - 8.4 7.0 11.8 54 4.5 0.0 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Pyr_redox_3 PF13738.1 CEH13613.1 - 1.7e-19 70.7 0.1 7.3e-18 65.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CEH13613.1 - 1.3e-18 66.5 0.0 8.9e-18 63.7 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 CEH13613.1 - 6.4e-13 49.0 0.4 1.1e-05 25.4 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEH13613.1 - 4.7e-11 42.1 1.6 2.6e-09 36.4 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 CEH13613.1 - 3.1e-09 36.2 1.1 1.4e-06 27.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CEH13613.1 - 8.3e-09 35.3 1.5 1.9e-07 31.0 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CEH13613.1 - 3.5e-06 27.3 7.5 0.0019 18.5 0.9 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CEH13613.1 - 1.6e-05 24.9 0.3 0.28 11.2 0.0 3.0 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 CEH13613.1 - 3.3e-05 23.7 3.7 0.0011 18.8 0.1 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 CEH13613.1 - 0.00046 19.8 2.3 0.00052 19.7 0.3 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CEH13613.1 - 0.0013 18.9 0.0 0.26 11.5 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 CEH13613.1 - 0.0017 17.5 0.2 0.0093 15.0 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 CEH13613.1 - 0.0017 17.7 0.3 0.0035 16.7 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 CEH13613.1 - 0.0029 16.7 3.2 0.048 12.7 0.3 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 CEH13613.1 - 0.011 14.6 6.3 0.13 11.0 0.7 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CEH13613.1 - 0.014 14.4 2.3 0.053 12.5 0.5 2.1 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.16 CEH13613.1 - 0.014 14.9 2.5 1.9 8.0 0.2 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 CEH13613.1 - 0.027 12.9 6.2 0.24 9.8 0.7 2.4 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.7 CEH13613.1 - 0.047 12.5 0.3 0.14 11.0 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_2 PF03446.10 CEH13613.1 - 0.051 13.4 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 CEH13613.1 - 0.085 12.5 1.0 0.23 11.1 0.7 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 CEH13613.1 - 0.12 11.5 0.5 9.2 5.3 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CEH13613.1 - 0.18 10.5 9.0 0.044 12.6 1.6 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_10 PF13460.1 CEH13613.1 - 0.76 9.7 3.8 0.63 10.0 0.3 2.4 3 0 0 3 3 3 0 NADH(P)-binding ThiF PF00899.16 CEH13613.1 - 5.2 6.8 5.6 6.4 6.5 0.4 2.4 2 0 0 2 2 2 0 ThiF family SNARE PF05739.14 CEH13614.1 - 1.6e-18 66.1 3.4 1.6e-18 66.1 2.4 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 CEH13614.1 - 5.7e-11 42.3 2.6 1.5e-10 40.9 0.4 2.4 2 1 0 2 2 2 1 Syntaxin-like protein Herpes_US9 PF06072.6 CEH13614.1 - 0.085 12.7 0.4 0.16 11.8 0.3 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 ATG16 PF08614.6 CEH13614.1 - 0.12 12.1 12.5 0.015 15.1 3.6 2.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Synaptobrevin PF00957.16 CEH13614.1 - 0.16 11.5 1.3 0.49 10.0 0.0 2.4 3 0 0 3 3 3 0 Synaptobrevin Syntaxin PF00804.20 CEH13614.1 - 2.1 8.5 10.4 0.36 11.0 0.3 3.4 1 1 1 3 3 3 0 Syntaxin SHR3_chaperone PF08229.6 CEH13615.1 - 3.5e-29 101.1 0.1 5.9e-29 100.4 0.0 1.4 1 1 0 1 1 1 1 ER membrane protein SH3 DSRB PF10781.4 CEH13615.1 - 0.048 13.1 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Dextransucrase DSRB DUF2231 PF09990.4 CEH13615.1 - 0.1 12.9 4.1 0.7 10.2 0.9 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF1656 PF07869.7 CEH13615.1 - 3.7 7.4 6.8 29 4.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) DUF605 PF04652.11 CEH13616.1 - 0.53 9.6 17.8 0.35 10.2 11.3 1.3 1 1 0 1 1 1 0 Vta1 like Glyco_hydro_15 PF00723.16 CEH13617.1 - 3.1e-49 167.7 0.0 1.5e-27 96.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 TMEM247 PF15444.1 CEH13618.1 - 0.63 9.8 2.2 2.2 8.0 1.6 1.9 1 0 0 1 1 1 0 Transmembrane protein 247 Bin3 PF06859.7 CEH13620.1 - 6.5e-25 87.2 0.0 1.1e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 CEH13620.1 - 1.1e-10 42.0 0.0 4.3e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH13620.1 - 1.7e-08 34.1 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH13620.1 - 6.9e-07 29.6 0.0 7.2e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH13620.1 - 1.7e-05 24.5 0.0 2.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH13620.1 - 8.6e-05 22.9 0.0 0.00026 21.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CEH13620.1 - 0.00022 20.3 0.1 0.0011 18.0 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 CEH13620.1 - 0.00045 20.5 0.0 0.0016 18.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH13620.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CEH13620.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FmrO PF07091.6 CEH13620.1 - 0.02 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_2 PF00891.13 CEH13620.1 - 0.12 11.5 0.0 4.6 6.3 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase Metallophos PF00149.23 CEH13621.1 - 3.8e-27 95.0 0.0 4.5e-22 78.4 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CEH13621.1 - 1e-19 69.9 5.3 5.2e-15 54.8 0.1 3.0 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 CEH13621.1 - 8.3e-15 53.6 1.2 0.0016 18.0 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat PPP5 PF08321.7 CEH13621.1 - 2.8e-10 40.0 0.0 8.3e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 PPP5 TPR repeat region TPR_2 PF07719.12 CEH13621.1 - 5.4e-09 35.2 3.9 0.013 15.3 0.0 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEH13621.1 - 0.00029 21.3 0.4 0.024 15.3 0.0 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEH13621.1 - 0.00045 20.6 0.7 1.1 10.0 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEH13621.1 - 0.0082 15.9 0.2 0.56 10.0 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEH13621.1 - 0.012 15.3 0.0 11 6.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CEH13621.1 - 0.022 14.9 0.1 1.1 9.6 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2408 PF10303.4 CEH13622.1 - 5.7e-52 175.3 0.5 4.2e-35 120.7 0.0 4.9 4 1 1 5 5 5 4 Protein of unknown function (DUF2408) DUF972 PF06156.8 CEH13622.1 - 0.048 14.0 0.0 1.8 8.9 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF972) CDC45 PF02724.9 CEH13622.1 - 0.075 11.0 2.6 0.16 10.0 1.8 1.4 1 0 0 1 1 1 0 CDC45-like protein IncA PF04156.9 CEH13622.1 - 0.11 12.1 1.9 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 IncA protein BUD22 PF09073.5 CEH13622.1 - 0.25 10.3 7.3 0.11 11.5 3.4 1.6 2 0 0 2 2 2 0 BUD22 PilJ PF13675.1 CEH13622.1 - 0.48 10.7 2.7 1.9 8.8 0.0 3.0 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Nop14 PF04147.7 CEH13622.1 - 7 4.4 11.3 0.75 7.6 4.5 1.7 2 0 0 2 2 2 0 Nop14-like family Pkinase PF00069.20 CEH13623.1 - 1.1e-56 191.8 0.0 1.6e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH13623.1 - 4.2e-19 68.6 0.0 7.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH13623.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CEH13623.1 - 0.016 14.5 0.1 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 CEH13623.1 - 0.12 11.4 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CEH13623.1 - 0.46 10.0 0.1 0.79 9.2 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Serinc PF03348.10 CEH13624.1 - 2.3e-139 464.8 0.1 2.7e-139 464.5 0.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Ribosomal_S8 PF00410.14 CEH13627.1 - 7.6e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S4e PF00900.15 CEH13628.1 - 5.9e-29 99.5 1.0 1.7e-28 98.0 0.1 2.1 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CEH13628.1 - 5.1e-20 71.0 3.6 9e-20 70.2 2.5 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 CEH13628.1 - 0.00018 21.1 2.0 0.00081 19.0 1.4 2.1 1 0 0 1 1 1 1 KOW motif S4 PF01479.20 CEH13628.1 - 0.00055 19.3 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain CwfJ_C_1 PF04677.10 CEH13629.1 - 7.8e-29 99.8 0.1 1.2e-28 99.2 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CEH13629.1 - 7.4e-17 61.6 0.4 1.2e-15 57.8 0.0 2.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 DUF410 PF04190.8 CEH13631.1 - 1.6e-21 77.0 0.0 4.3e-16 59.2 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF410) TPR_19 PF14559.1 CEH13631.1 - 0.044 14.1 0.6 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CEH13631.1 - 0.11 13.2 1.0 0.57 10.9 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_S49 PF01343.13 CEH13632.1 - 5.8e-45 152.8 0.0 1.8e-29 102.4 0.0 2.8 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.18 CEH13632.1 - 0.0018 17.9 0.1 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 Clp protease Glyco_trans_1_4 PF13692.1 CEH13633.1 - 3.5e-16 59.5 0.1 1.7e-13 50.8 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CEH13633.1 - 1.7e-06 28.2 13.9 1.7e-06 28.2 9.7 2.9 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 CEH13633.1 - 6.7e-06 26.2 0.0 2.7e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CEH13633.1 - 0.0064 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Actin PF00022.14 CEH13638.1 - 6.3e-18 64.3 0.0 9e-08 30.9 0.0 2.5 3 0 0 3 3 3 2 Actin Aminotran_1_2 PF00155.16 CEH13639.1 - 5.4e-18 65.0 0.0 7.1e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CEH13639.1 - 0.00023 19.8 0.0 0.00083 18.0 0.0 1.8 1 1 1 2 2 2 1 Alanine-glyoxylate amino-transferase zf-C2H2_4 PF13894.1 CEH13640.1 - 0.017 15.4 10.4 1.5 9.3 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEH13640.1 - 0.22 11.8 3.6 3.3 8.1 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 CEH13640.1 - 0.81 10.1 15.9 2.5 8.6 0.6 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type Lon_C PF05362.8 CEH13643.1 - 2.2e-62 210.0 0.0 3.3e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CEH13643.1 - 1.4e-23 83.5 0.0 3.4e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CEH13643.1 - 1.7e-09 37.5 0.0 4.9e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 CEH13643.1 - 1.3e-08 34.4 0.0 2.9e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase LON PF02190.11 CEH13643.1 - 1e-07 31.8 0.0 2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_22 PF13401.1 CEH13643.1 - 9.4e-05 22.5 0.2 0.0057 16.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEH13643.1 - 9.5e-05 23.2 2.3 0.0003 21.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEH13643.1 - 0.00013 22.0 0.1 0.00013 22.0 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 CEH13643.1 - 0.00024 20.7 1.3 0.00061 19.4 0.2 2.3 2 0 0 2 2 1 1 Part of AAA domain AAA_2 PF07724.9 CEH13643.1 - 0.00096 19.0 0.0 0.0036 17.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CEH13643.1 - 0.0018 17.4 0.0 0.0055 15.8 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CEH13643.1 - 0.0021 17.5 0.2 0.0074 15.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CEH13643.1 - 0.0033 17.0 0.0 0.0087 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CEH13643.1 - 0.0034 17.2 0.0 0.0034 17.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CEH13643.1 - 0.0041 16.5 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 CEH13643.1 - 0.0055 15.7 0.1 0.022 13.7 0.1 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus G-alpha PF00503.15 CEH13643.1 - 0.018 13.7 1.0 0.027 13.1 0.7 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.1 CEH13643.1 - 0.019 15.2 0.1 0.019 15.2 0.1 2.1 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 CEH13643.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CEH13643.1 - 0.03 13.0 0.0 0.11 11.2 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus RNA_helicase PF00910.17 CEH13643.1 - 0.03 14.4 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_PrkA PF08298.6 CEH13643.1 - 0.032 12.9 0.0 0.62 8.6 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain KTI12 PF08433.5 CEH13643.1 - 0.036 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 CEH13643.1 - 0.043 13.4 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 CEH13643.1 - 0.044 13.3 0.1 0.076 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CEH13643.1 - 0.05 13.3 0.3 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CEH13643.1 - 0.054 13.1 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 CEH13643.1 - 0.068 12.2 0.1 0.068 12.2 0.1 2.2 1 1 1 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 CEH13643.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 CEH13643.1 - 0.12 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 CEH13643.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 CEH13643.1 - 0.87 9.8 4.4 0.36 11.1 0.1 2.4 2 1 1 3 3 2 0 ABC transporter Ycf1 PF05758.7 CEH13643.1 - 1.8 6.1 1.5 2.6 5.6 1.0 1.1 1 0 0 1 1 1 0 Ycf1 M PF02370.11 CEH13643.1 - 3.2 8.4 7.5 24 5.7 0.4 3.4 2 0 0 2 2 2 0 M protein repeat AAA_11 PF13086.1 CEH13643.1 - 8.9 5.8 8.4 0.42 10.1 0.1 2.3 1 1 1 2 2 1 0 AAA domain Pro_CA PF00484.14 CEH13644.1 - 2e-40 138.2 0.1 2.5e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DUF2922 PF11148.3 CEH13644.1 - 0.091 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) HEAT_2 PF13646.1 CEH13645.1 - 2e-06 27.9 9.5 0.0002 21.5 0.0 5.1 3 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 CEH13645.1 - 0.0003 20.6 3.3 0.94 9.7 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat UME PF08064.8 CEH13645.1 - 0.015 15.2 0.1 0.095 12.6 0.0 2.4 2 0 0 2 2 2 0 UME (NUC010) domain MutS_II PF05188.12 CEH13645.1 - 0.042 13.9 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 MutS domain II HEAT_EZ PF13513.1 CEH13645.1 - 2.1 8.9 13.8 14 6.3 0.1 5.8 4 2 2 6 6 6 0 HEAT-like repeat MFS_1 PF07690.11 CEH13646.1 - 3.1e-15 55.7 24.7 8.1e-15 54.3 17.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 CEH13646.1 - 2.2e-10 40.2 0.9 6.4e-10 38.7 0.6 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Pyr_redox_3 PF13738.1 CEH13647.1 - 7.1e-25 88.2 0.0 1e-24 87.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CEH13647.1 - 7e-11 41.0 0.2 1e-09 37.1 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 CEH13647.1 - 3.1e-08 33.5 0.0 4.2e-06 26.6 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CEH13647.1 - 1.7e-07 30.4 0.2 8.9e-06 24.8 0.0 2.8 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 CEH13647.1 - 7.7e-06 25.1 0.3 0.0082 15.2 0.0 2.8 3 0 0 3 3 3 2 Thi4 family DAO PF01266.19 CEH13647.1 - 3e-05 23.0 1.0 0.0043 15.9 0.1 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CEH13647.1 - 7.4e-05 23.0 0.5 0.57 10.6 0.0 3.9 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEH13647.1 - 0.00029 20.7 0.0 0.14 11.9 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEH13647.1 - 0.0014 17.7 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 CEH13647.1 - 0.0078 16.3 0.0 0.28 11.2 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Mqo PF06039.10 CEH13647.1 - 0.0094 14.1 0.1 0.27 9.3 0.0 2.2 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.17 CEH13647.1 - 0.013 14.3 0.2 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CEH13647.1 - 0.015 14.1 0.0 0.19 10.5 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.1 CEH13647.1 - 0.09 13.0 0.0 0.61 10.3 0.0 2.3 3 0 0 3 3 3 0 Putative NAD(P)-binding Ras PF00071.17 CEH13648.1 - 2e-54 183.3 0.0 2.3e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH13648.1 - 2.1e-19 70.1 0.0 2.7e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH13648.1 - 1.2e-14 53.9 0.0 1.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CEH13648.1 - 8.9e-05 22.4 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEH13648.1 - 0.00023 20.6 0.0 0.00056 19.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEH13648.1 - 0.002 17.2 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CEH13648.1 - 0.012 14.8 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 CEH13648.1 - 0.097 12.2 0.1 0.18 11.3 0.0 1.5 1 1 1 2 2 2 0 AAA domain Mito_carr PF00153.22 CEH13650.1 - 3.7e-66 218.8 4.8 2.8e-25 87.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CEH13650.1 - 2e-06 27.9 5.3 0.00066 19.7 0.0 3.1 2 1 1 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family Fn3_assoc PF13287.1 CEH13650.1 - 0.1 12.7 0.1 1.6 8.9 0.0 2.8 2 1 0 2 2 2 0 Fn3 associated SQS_PSY PF00494.14 CEH13651.1 - 1.6e-54 185.0 3.0 2.3e-54 184.4 2.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase D-ser_dehydrat PF14031.1 CEH13652.1 - 5e-16 58.6 0.6 7.9e-15 54.8 0.1 2.6 2 1 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 CEH13652.1 - 2.2e-11 43.7 0.1 4.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Metallophos PF00149.23 CEH13653.1 - 1.3e-14 54.1 0.0 3.2e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEH13653.1 - 0.0087 15.9 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ORC2 PF04084.9 CEH13654.1 - 6.5e-30 104.0 0.0 1.1e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.14 CEH13654.1 - 2.1 8.2 28.3 0.089 12.5 1.2 4.2 4 0 0 4 4 4 0 AT hook motif PHF5 PF03660.9 CEH13655.1 - 7.9e-31 106.3 3.1 1.2e-23 83.1 1.6 2.0 1 1 1 2 2 2 2 PHF5-like protein UPF0547 PF10571.4 CEH13655.1 - 0.036 13.7 2.1 0.036 13.7 1.5 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Fer4_8 PF13183.1 CEH13655.1 - 0.39 10.7 5.5 32 4.6 3.8 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Sec1 PF00995.18 CEH13656.1 - 6.6e-141 470.7 0.0 7.6e-141 470.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family FUN14 PF04930.10 CEH13657.1 - 9.8e-21 73.9 0.9 1.2e-20 73.5 0.6 1.1 1 0 0 1 1 1 1 FUN14 family GST_N_2 PF13409.1 CEH13658.1 - 1.4e-18 66.6 0.0 3.6e-18 65.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CEH13658.1 - 1.8e-13 50.1 0.0 4.3e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEH13658.1 - 2.7e-08 33.6 0.0 4.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEH13658.1 - 1.2e-05 25.7 0.0 5.2e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CEH13658.1 - 7.8e-05 22.8 0.0 0.57 10.4 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain tRNA-synt_1d PF00750.14 CEH13659.1 - 1.2e-78 264.4 1.5 1.6e-78 264.0 1.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CEH13659.1 - 1.3e-21 76.7 0.1 2.9e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Methyltransf_18 PF12847.2 CEH13660.1 - 6.6e-13 49.2 0.1 3e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH13660.1 - 2.7e-07 30.4 0.0 4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH13660.1 - 1.2e-05 25.5 0.0 2.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH13660.1 - 7e-05 23.2 0.1 0.00028 21.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH13660.1 - 0.00015 22.1 0.0 0.00094 19.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH13660.1 - 0.00028 20.5 0.0 0.0019 17.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain SIMPL PF04402.9 CEH13660.1 - 0.0023 17.8 0.5 0.0045 16.8 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF541) Methyltransf_4 PF02390.12 CEH13660.1 - 0.0035 16.4 0.1 0.0082 15.2 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase RrnaAD PF00398.15 CEH13660.1 - 0.03 13.3 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 CEH13660.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CEH13660.1 - 0.08 12.3 0.3 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain DUF1752 PF08550.5 CEH13661.1 - 9e-11 41.1 5.3 1.1e-10 40.8 2.7 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) RRN3 PF05327.6 CEH13661.1 - 0.65 8.0 4.3 0.97 7.4 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 tRNA-synt_2 PF00152.15 CEH13663.1 - 3e-57 193.9 0.0 2.3e-46 158.1 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) ThiF PF00899.16 CEH13667.1 - 3.9e-47 159.5 0.1 3.2e-27 95.0 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 CEH13667.1 - 2.4e-39 134.3 0.0 5.8e-39 133.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 CEH13667.1 - 8.1e-39 131.0 1.9 9.2e-28 95.6 0.1 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CEH13667.1 - 7.1e-24 82.9 1.9 8.1e-21 73.1 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Ribosomal_L33 PF00471.15 CEH13668.1 - 4.8e-12 45.9 0.0 5.6e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 UCH PF00443.24 CEH13670.1 - 1.3e-43 149.0 0.0 2.1e-43 148.3 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEH13670.1 - 5.3e-17 62.1 0.0 9.3e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Arginosuc_synth PF00764.14 CEH13671.1 - 8.6e-151 502.3 0.0 1e-150 502.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 CEH13671.1 - 0.00087 18.6 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 CEH13671.1 - 0.058 11.9 0.0 0.086 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.16 CEH13671.1 - 0.091 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Aminotran_3 PF00202.16 CEH13672.1 - 3.9e-66 223.2 0.0 5e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CEH13672.1 - 0.00055 18.9 0.0 0.00078 18.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CEH13672.1 - 0.0098 14.4 0.1 0.03 12.8 0.0 1.8 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase Thiolase_N PF00108.18 CEH13673.1 - 3.3e-81 272.1 0.3 4e-81 271.8 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CEH13673.1 - 1.2e-40 137.7 2.3 2.2e-40 136.9 0.3 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CEH13673.1 - 9e-05 22.0 1.1 0.0002 20.9 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Rsa3 PF14615.1 CEH13674.1 - 3.2e-09 35.9 0.1 1.2e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Ribosome-assembly protein 3 NST1 PF13945.1 CEH13674.1 - 0.28 11.2 9.3 0.36 10.8 6.4 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF1771 PF08590.5 CEH13675.1 - 1.3e-23 82.7 6.7 1.3e-23 82.7 4.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 CEH13675.1 - 2e-16 59.9 2.1 3.9e-16 58.9 0.2 2.4 2 0 0 2 2 2 1 Smr domain Tropomyosin PF00261.15 CEH13675.1 - 0.045 12.8 1.9 0.074 12.1 1.3 1.3 1 0 0 1 1 1 0 Tropomyosin Chorion_3 PF05387.6 CEH13675.1 - 1.8 7.9 12.4 0.21 10.9 3.4 2.2 2 0 0 2 2 2 0 Chorion family 3 Med15 PF09606.5 CEH13675.1 - 2.8 6.0 27.2 3.3 5.7 18.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Rotamase PF00639.16 CEH13675.1 - 2.9 8.7 7.2 0.78 10.5 1.8 2.4 2 1 0 2 2 2 0 PPIC-type PPIASE domain DUF1843 PF08898.5 CEH13675.1 - 3.7 7.6 7.6 8.3 6.5 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) ATP-synt_B PF00430.13 CEH13675.1 - 9.3 6.0 9.1 2 8.2 2.4 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF2828 PF11443.3 CEH13676.1 - 9.3e-108 360.7 0.0 2.2e-95 319.8 0.0 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) Ribosomal_S2 PF00318.15 CEH13678.1 - 1.9e-40 138.3 0.0 2.9e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S2 DUF3721 PF12518.3 CEH13678.1 - 0.041 13.4 0.0 0.15 11.6 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function FlxA PF14282.1 CEH13679.1 - 0.12 12.3 5.4 0.15 12.0 3.8 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF4407 PF14362.1 CEH13679.1 - 0.96 8.3 8.7 1.1 8.1 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.6 CEH13679.1 - 1.7 8.3 7.1 1.2 8.8 1.4 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 HrpA_pilin PF09589.5 CEH13679.1 - 1.8 9.0 7.1 7.7 6.9 4.9 1.8 1 1 0 1 1 1 0 HrpA pilus formation protein DUF3435 PF11917.3 CEH13679.1 - 2 7.0 9.1 2.2 6.8 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF4140 PF13600.1 CEH13679.1 - 2.6 8.5 11.5 7.9 6.9 0.4 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4463 PF14703.1 CEH13679.1 - 4.1 7.9 7.7 4.8 7.7 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) DivIC PF04977.10 CEH13679.1 - 4.6 6.8 11.2 0.75 9.3 1.4 2.2 1 1 1 2 2 2 0 Septum formation initiator ABC_tran_2 PF12848.2 CEH13679.1 - 4.9 7.0 10.5 7.4 6.4 1.1 2.1 2 0 0 2 2 2 0 ABC transporter Kinesin PF00225.18 CEH13680.1 - 3.3e-96 321.9 0.1 3.7e-96 321.7 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain UpxZ PF06603.6 CEH13680.1 - 0.038 14.0 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists AAA_22 PF13401.1 CEH13680.1 - 0.066 13.3 0.1 0.17 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 CEH13680.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein ADH_zinc_N PF00107.21 CEH13681.1 - 1e-09 38.0 0.7 1.5e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH13681.1 - 0.0029 18.4 0.1 0.0072 17.2 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CEH13681.1 - 0.047 13.6 0.2 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF72 PF01904.13 CEH13681.1 - 0.088 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF72 Epimerase PF01370.16 CEH13681.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 CEH13681.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RE_SinI PF09570.5 CEH13682.1 - 0.083 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 SinI restriction endonuclease XPC-binding PF09280.6 CEH13682.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 XPC-binding domain Mito_carr PF00153.22 CEH13683.1 - 1.6e-45 152.7 1.2 1.2e-21 76.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_Me_trans PF04252.8 CEH13684.1 - 1.7e-16 60.1 0.0 9.2e-14 51.2 0.0 2.4 2 0 0 2 2 2 2 Predicted SAM-dependent RNA methyltransferase UDG PF03167.14 CEH13685.1 - 0.0092 15.4 0.0 0.023 14.1 0.0 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily 5-FTHF_cyc-lig PF01812.15 CEH13686.1 - 3.5e-22 79.0 0.0 4e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Flg_hook PF02120.11 CEH13687.1 - 0.054 13.1 0.3 0.06 13.0 0.2 1.1 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK DUF3818 PF12825.2 CEH13688.1 - 4.3e-43 147.3 0.0 7.8e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CEH13688.1 - 7.9e-25 87.0 0.1 1.6e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 PX-associated Zn_clus PF00172.13 CEH13689.1 - 1.8e-08 34.1 9.2 3e-08 33.4 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MRG PF05712.8 CEH13690.1 - 1e-54 184.4 0.0 1.5e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 CEH13690.1 - 1.8e-10 40.3 0.1 4.2e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chorion_2 PF03964.10 CEH13690.1 - 0.02 15.4 11.0 0.61 10.6 4.5 2.4 2 0 0 2 2 2 0 Chorion family 2 Chromo PF00385.19 CEH13690.1 - 0.12 12.0 1.2 0.32 10.7 0.9 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Gly-zipper_OmpA PF13436.1 CEH13690.1 - 0.29 10.7 18.4 0.92 9.1 9.5 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Shadoo PF14999.1 CEH13690.1 - 0.49 10.2 17.0 0.093 12.5 6.0 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective ORC6 PF05460.8 CEH13691.1 - 0.87 8.6 7.4 1.3 8.0 3.4 1.9 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF1691 PF07950.6 CEH13693.1 - 2.5e-08 33.8 3.3 9.2e-07 28.7 0.2 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 CEH13693.1 - 0.076 12.8 2.3 0.85 9.4 0.1 2.4 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DnaJ PF00226.26 CEH13695.1 - 1.9e-10 40.3 0.0 3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Syntaxin PF00804.20 CEH13696.1 - 1.4e-15 57.2 15.6 9.6e-15 54.6 4.6 2.3 2 0 0 2 2 2 2 Syntaxin SNARE PF05739.14 CEH13696.1 - 8.1e-14 51.0 5.8 8.1e-14 51.0 4.0 2.9 2 1 0 2 2 2 1 SNARE domain Flu_NS2 PF00601.14 CEH13696.1 - 0.003 17.7 2.7 0.97 9.6 0.1 2.5 2 0 0 2 2 2 2 Influenza non-structural protein (NS2) Allexi_40kDa PF05549.6 CEH13696.1 - 0.075 12.3 6.6 0.052 12.8 0.9 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Syntaxin_2 PF14523.1 CEH13696.1 - 0.18 11.8 13.6 0.28 11.2 5.7 2.6 2 1 0 2 2 2 0 Syntaxin-like protein Vac_Fusion PF02346.11 CEH13696.1 - 0.19 11.1 2.5 9.2 5.7 0.1 3.2 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Spectrin PF00435.16 CEH13696.1 - 0.21 11.9 7.7 0.3 11.3 1.1 2.6 2 0 0 2 2 2 0 Spectrin repeat BLOC1_2 PF10046.4 CEH13696.1 - 0.28 11.3 10.1 0.44 10.7 0.5 3.3 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 CEH13696.1 - 0.43 10.3 12.5 0.42 10.4 2.9 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4094 PF13334.1 CEH13696.1 - 0.43 10.9 0.1 0.43 10.9 0.1 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4094) HeLo PF14479.1 CEH13696.1 - 0.73 9.5 11.2 1.4 8.6 3.0 2.3 1 1 0 2 2 2 0 Prion-inhibition and propagation Fib_alpha PF08702.5 CEH13696.1 - 5 7.2 14.4 3.5 7.7 0.3 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Cauli_AT PF03233.8 CEH13696.1 - 6.6 6.4 8.5 13 5.4 1.6 2.5 2 1 0 2 2 2 0 Aphid transmission protein FUSC PF04632.7 CEH13696.1 - 7 4.9 7.9 1.2 7.5 2.2 1.7 1 1 0 2 2 2 0 Fusaric acid resistance protein family DUF3811 PF11656.3 CEH13696.1 - 7.9 6.6 9.7 94 3.1 6.8 2.5 1 1 0 1 1 1 0 YjbD family (DUF3811) tRNA-synt_2 PF00152.15 CEH13697.1 - 1.6e-87 293.4 0.0 2e-87 293.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CEH13697.1 - 3e-13 49.4 0.0 8.3e-13 48.0 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CEH13697.1 - 2.3e-08 33.5 0.0 0.0001 21.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CEH13697.1 - 0.003 17.1 0.1 0.93 9.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) DUF2276 PF10040.4 CEH13697.1 - 0.04 14.1 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2276) Ribosomal_60s PF00428.14 CEH13697.1 - 4.5 7.7 15.2 25 5.3 0.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein LIP PF03583.9 CEH13698.1 - 5.7e-62 209.5 0.0 8.3e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase DcpS_C PF11969.3 CEH13699.1 - 1.1e-23 83.6 0.0 1.8e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 CEH13699.1 - 6.3e-22 78.0 0.0 1.4e-21 76.9 0.0 1.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.18 CEH13699.1 - 0.099 13.1 1.1 0.54 10.8 0.7 2.2 1 1 0 1 1 1 0 HIT domain DPPIV_N PF00930.16 CEH13700.1 - 2.6e-81 272.9 0.0 4e-81 272.3 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CEH13700.1 - 7.4e-44 149.5 0.4 1.2e-43 148.8 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CEH13700.1 - 1.4e-05 24.8 0.0 3.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 CEH13700.1 - 0.072 11.5 0.0 0.2 10.1 0.0 1.7 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Amnionless PF14828.1 CEH13700.1 - 0.073 11.5 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 Amnionless Nucleo_P87 PF07267.6 CEH13701.1 - 0.027 13.1 8.5 0.041 12.5 5.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Hex_IIIa PF02455.11 CEH13701.1 - 4.3 5.9 8.6 7.3 5.1 5.9 1.4 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) MAP65_ASE1 PF03999.7 CEH13701.1 - 9.9 4.6 10.3 15 3.9 7.1 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) E1-E2_ATPase PF00122.15 CEH13702.1 - 2.2e-26 92.3 0.0 5.7e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.3 CEH13702.1 - 2e-25 88.9 0.0 4.5e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 CEH13702.1 - 6.8e-24 85.0 0.0 1.5e-23 83.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEH13702.1 - 8.4e-22 78.6 0.0 1.5e-19 71.2 0.0 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CEH13702.1 - 3.2e-05 23.5 6.4 7.7e-05 22.2 4.4 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 CEH13702.1 - 4.4e-05 23.3 0.1 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CEH13702.1 - 0.0012 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEH13702.1 - 0.0024 17.5 0.0 0.46 10.0 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FliJ PF02050.11 CEH13705.1 - 0.0016 18.4 3.5 0.0016 18.4 2.4 2.8 1 1 1 2 2 2 1 Flagellar FliJ protein DUF812 PF05667.6 CEH13705.1 - 1 7.7 20.8 0.27 9.6 9.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Scaffolding_pro PF11418.3 CEH13705.1 - 1.3 9.4 7.5 0.42 10.9 2.2 2.3 2 0 0 2 2 2 0 Phi29 scaffolding protein BTV_NS2 PF04514.7 CEH13705.1 - 2 7.2 8.7 3.1 6.6 6.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 IncA PF04156.9 CEH13705.1 - 3.6 7.1 19.0 1.1e+02 2.3 13.2 2.3 1 1 0 1 1 1 0 IncA protein Spc7 PF08317.6 CEH13705.1 - 4.4 5.8 12.6 2.5 6.6 5.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein OTU PF02338.14 CEH13710.1 - 9.2e-06 26.2 0.0 1.8e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Zn_ribbon_recom PF13408.1 CEH13710.1 - 0.026 14.7 0.4 0.05 13.8 0.3 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Kelch_3 PF13415.1 CEH13711.1 - 1.1e-22 79.5 5.6 2e-06 27.7 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CEH13711.1 - 3.1e-18 65.2 10.1 8.5e-06 25.4 0.4 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CEH13711.1 - 5.3e-13 48.6 0.0 0.021 14.8 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 CEH13711.1 - 8.4e-11 41.5 0.1 0.0013 18.8 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 CEH13711.1 - 3.1e-08 33.0 0.0 0.039 13.5 0.0 4.3 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 CEH13711.1 - 0.00045 19.8 0.9 0.27 11.0 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Acetyltransf_1 PF00583.19 CEH13712.1 - 9.2e-17 60.8 0.1 1.7e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEH13712.1 - 6.2e-10 39.2 0.0 1.4e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEH13712.1 - 1.2e-09 37.7 0.1 2e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CEH13712.1 - 5.8e-07 29.4 0.0 9.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEH13712.1 - 8.4e-07 29.2 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CEH13712.1 - 6.1e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEH13712.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Catalase PF00199.14 CEH13713.1 - 6.9e-153 508.8 0.1 8.9e-153 508.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CEH13713.1 - 2.2e-14 53.0 0.3 5.9e-14 51.6 0.1 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive DUF3115 PF11312.3 CEH13714.1 - 0.15 10.9 1.1 5.1 5.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3115) Spc97_Spc98 PF04130.8 CEH13715.1 - 3.9e-43 147.6 0.0 5.8e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family F-box PF00646.28 CEH13715.1 - 0.24 11.0 1.9 1.4 8.6 0.2 2.5 2 0 0 2 2 2 0 F-box domain Actin PF00022.14 CEH13717.1 - 2.2e-134 447.8 0.0 2.7e-134 447.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CEH13717.1 - 0.022 13.3 0.0 2.7 6.5 0.0 2.7 2 1 0 2 2 2 0 MreB/Mbl protein Pkinase PF00069.20 CEH13718.1 - 3.8e-60 203.2 0.0 1e-37 129.7 0.0 4.5 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CEH13718.1 - 8.1e-29 100.4 0.0 1.6e-16 60.2 0.0 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 CEH13718.1 - 6.8e-21 74.6 0.0 1.3e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs RWD PF05773.17 CEH13718.1 - 1.2e-10 41.2 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 CEH13718.1 - 9.3e-08 31.4 0.0 9.3e-08 31.4 0.0 3.1 3 0 0 3 3 3 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 CEH13718.1 - 0.0005 19.1 0.1 0.0018 17.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like HGTP_anticodon PF03129.15 CEH13718.1 - 0.00055 19.8 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Seadorna_VP7 PF07387.6 CEH13718.1 - 1.1 8.0 0.0 1.9 7.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 VCBS PF13517.1 CEH13719.1 - 6.7e-24 84.0 9.0 6.7e-07 29.5 0.5 5.9 4 2 2 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CEH13719.1 - 5.8e-15 54.4 12.4 0.00027 20.5 0.0 6.5 6 0 0 6 6 6 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 CEH13719.1 - 7.4e-09 35.2 4.4 1.1 8.7 0.0 6.1 4 2 2 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region CoA_transf_3 PF02515.12 CEH13720.1 - 2.7e-45 153.9 0.0 5.7e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 CoA-transferase family III adh_short PF00106.20 CEH13721.1 - 5.9e-08 32.8 0.0 1.2e-07 31.7 0.0 1.5 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH13721.1 - 0.00091 19.0 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AhpC-TSA_2 PF13911.1 CEH13722.1 - 5.6e-14 52.0 0.0 7.6e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 CEH13722.1 - 0.00046 19.8 0.0 0.0031 17.1 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CEH13722.1 - 0.00085 18.8 0.0 0.0019 17.7 0.0 1.5 1 1 0 1 1 1 1 Redoxin Cytochrom_C PF00034.16 CEH13723.1 - 8.1e-10 39.4 0.1 1.7e-09 38.3 0.1 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CEH13723.1 - 9.2e-09 35.3 2.4 1.5e-07 31.4 1.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CEH13723.1 - 0.0026 17.1 1.1 0.016 14.6 0.8 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.9 CEH13723.1 - 0.051 13.8 0.0 0.062 13.6 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase UPF0128 PF03673.8 CEH13723.1 - 0.065 12.4 0.1 0.073 12.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) Haem_bd PF14376.1 CEH13723.1 - 0.13 11.9 0.1 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Haem-binding domain Asn_synthase PF00733.16 CEH13724.1 - 1.7e-32 112.8 0.3 2.2e-32 112.5 0.2 1.1 1 0 0 1 1 1 1 Asparagine synthase RTA1 PF04479.8 CEH13725.1 - 1e-32 113.4 3.1 1.5e-32 112.9 2.1 1.1 1 0 0 1 1 1 1 RTA1 like protein CRAL_TRIO PF00650.15 CEH13726.1 - 6.3e-31 107.0 0.1 9.6e-31 106.4 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEH13726.1 - 1.5e-12 47.4 0.3 4.4e-12 45.9 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CEH13726.1 - 5.7e-06 26.3 0.0 9.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MFS_1 PF07690.11 CEH13727.1 - 1.9e-23 82.7 39.7 6.2e-14 51.4 7.2 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH13727.1 - 7.3e-11 41.2 18.7 6.9e-09 34.7 1.9 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter DUF2380 PF09533.5 CEH13728.1 - 0.013 14.8 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) NodZ PF05830.6 CEH13728.1 - 0.042 12.4 0.2 0.043 12.4 0.1 1.0 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Cyclin_N PF00134.18 CEH13729.1 - 1.2e-43 147.7 0.1 1.4e-41 141.0 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CEH13729.1 - 4.7e-31 107.1 0.2 8.6e-31 106.3 0.2 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Arrestin_N PF00339.24 CEH13730.1 - 0.0019 18.0 0.1 0.007 16.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_S8e PF01201.17 CEH13732.1 - 2.4e-47 160.3 1.8 3e-47 160.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Zip PF02535.17 CEH13733.1 - 1.3e-34 119.6 2.0 3.1e-34 118.4 1.4 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter ETF PF01012.16 CEH13734.1 - 3e-40 137.6 0.3 3e-40 137.6 0.2 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 CEH13734.1 - 9.7e-36 121.2 0.1 2.2e-35 120.1 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain EMP24_GP25L PF01105.19 CEH13735.1 - 3.6e-45 153.9 0.0 4.3e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CDC37_N PF03234.9 CEH13736.1 - 1.2e-46 159.2 4.0 1.2e-46 159.2 2.8 1.6 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_C PF08564.5 CEH13736.1 - 3.7e-21 74.8 0.4 3.7e-21 74.8 0.3 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain HTH_22 PF13309.1 CEH13736.1 - 0.035 13.8 1.2 0.12 12.1 0.1 2.3 2 0 0 2 2 2 0 HTH domain Peptidase_S30 PF01577.11 CEH13736.1 - 0.094 12.1 2.4 0.23 10.8 1.7 1.6 1 0 0 1 1 1 0 Potyvirus P1 protease V-SNARE PF05008.10 CEH13736.1 - 2.4 8.3 7.7 0.42 10.8 0.3 3.1 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DASH_Duo1 PF08651.5 CEH13737.1 - 1.1e-19 69.7 0.0 1.7e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF572 PF04502.8 CEH13737.1 - 8.4 5.5 8.6 0.1 11.7 0.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) Lipase_3 PF01764.20 CEH13738.1 - 3.6e-15 55.8 0.0 5.5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CEH13738.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH13738.1 - 0.029 14.2 0.1 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CEH13738.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein zf-C2H2 PF00096.21 CEH13739.1 - 4.4e-09 36.1 17.9 8.6e-06 25.8 2.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 CEH13739.1 - 2e-07 30.8 5.5 2e-07 30.8 3.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 CEH13739.1 - 0.0053 17.0 16.1 0.18 12.2 1.8 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger Fer4_17 PF13534.1 CEH13739.1 - 1 9.7 12.4 2.1 8.7 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain RRM_1 PF00076.17 CEH13740.1 - 3.6e-32 109.8 0.0 4.2e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH13740.1 - 1.3e-27 95.5 0.0 7e-13 48.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH13740.1 - 1.1e-09 38.0 0.0 0.00022 21.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBFB_NFYA PF02045.10 CEH13741.1 - 1.4e-10 41.5 5.0 1.4e-10 41.5 3.5 2.3 3 0 0 3 3 3 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B VWA_CoxE PF05762.9 CEH13741.1 - 0.067 12.3 1.1 0.14 11.3 0.8 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DUF221 PF02714.10 CEH13742.1 - 1.9e-71 240.6 18.7 7.9e-38 130.1 5.8 2.4 1 1 1 2 2 2 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 CEH13742.1 - 1.1e-36 125.7 1.3 1.1e-36 125.7 0.9 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CEH13742.1 - 1.7e-21 76.4 0.8 3.2e-21 75.6 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 CEH13742.1 - 6e-12 45.2 0.0 1.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein JAB PF01398.16 CEH13743.1 - 3.4e-26 91.2 0.1 5.2e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CEH13743.1 - 4.1e-06 26.3 0.0 1.3e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CEH13743.1 - 0.051 13.0 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Nefa_Nip30_N PF10187.4 CEH13744.1 - 7.1e-27 93.5 14.8 7.1e-27 93.5 10.2 2.0 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 HMG-CoA_red PF00368.13 CEH13745.1 - 2.1e-153 510.4 5.5 2.8e-153 510.0 3.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 CEH13745.1 - 4.7e-17 61.8 2.1 2e-07 30.5 0.1 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CEH13745.1 - 0.0089 14.0 0.8 0.13 10.1 0.0 2.2 2 0 0 2 2 2 1 Patched family Zn_clus PF00172.13 CEH13747.1 - 4.2e-07 29.7 11.1 4.2e-07 29.7 7.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNase_NucA_NucB PF14040.1 CEH13748.1 - 2.9e-26 91.8 2.5 4.1e-26 91.3 1.7 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Redoxin PF08534.5 CEH13749.1 - 2.1e-29 101.9 0.0 2.4e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CEH13749.1 - 1.3e-13 50.6 0.0 1.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF4406 PF14359.1 CEH13749.1 - 0.0075 16.3 0.1 0.78 9.8 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4406) DJ-1_PfpI PF01965.19 CEH13750.1 - 1.1e-30 105.9 0.3 1.6e-30 105.5 0.2 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CEH13750.1 - 1.3e-15 57.1 0.0 1.7e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 CEH13750.1 - 0.0064 16.0 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain VWA_2 PF13519.1 CEH13750.1 - 0.02 14.9 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Glyco_transf_41 PF13844.1 CEH13751.1 - 1.9e-98 329.4 0.0 3.5e-46 157.1 0.0 4.2 4 0 0 4 4 4 3 Glycosyl transferase family 41 TPR_11 PF13414.1 CEH13751.1 - 6.8e-22 76.8 7.7 1.9e-09 36.9 0.3 5.0 5 0 0 5 5 4 3 TPR repeat TPR_1 PF00515.23 CEH13751.1 - 1.3e-20 72.0 0.3 1.8e-06 27.2 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEH13751.1 - 6.1e-17 61.3 0.9 9.7e-09 35.0 0.0 4.6 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CEH13751.1 - 1.2e-15 56.3 8.0 0.00059 19.8 0.0 7.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEH13751.1 - 5.4e-15 54.0 4.7 0.00013 21.5 0.0 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 CEH13751.1 - 4.9e-12 44.7 0.0 0.0012 18.5 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH13751.1 - 1.7e-11 43.6 4.2 0.0033 17.9 0.0 6.8 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 CEH13751.1 - 2.3e-10 40.0 7.0 0.028 14.3 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEH13751.1 - 6.7e-10 38.0 0.5 0.086 12.6 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEH13751.1 - 1.4e-07 31.7 1.0 0.97 9.8 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEH13751.1 - 5.8e-07 30.0 15.4 0.0019 18.8 0.0 6.4 5 1 2 7 7 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 CEH13751.1 - 0.00062 20.0 0.0 3.2 8.4 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CEH13751.1 - 0.033 14.3 0.9 3.4 7.8 0.1 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Tcf25 PF04910.9 CEH13751.1 - 0.13 11.2 0.5 0.34 9.8 0.3 1.6 1 0 0 1 1 1 0 Transcriptional repressor TCF25 DUF247 PF03140.10 CEH13751.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function Rdx PF10262.4 CEH13752.1 - 3.1e-15 55.9 0.0 6.5e-15 54.9 0.0 1.5 1 1 0 1 1 1 1 Rdx family Ribosomal_L22 PF00237.14 CEH13754.1 - 8.8e-20 70.6 0.9 1.4e-19 69.9 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Sec8_exocyst PF04048.9 CEH13755.1 - 2e-37 127.9 0.0 4.1e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 CEH13755.1 - 1.9e-06 27.0 0.1 3.7e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF3090 PF11290.3 CEH13755.1 - 0.0065 15.9 0.1 3.4 7.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3090) COG2 PF06148.6 CEH13755.1 - 0.027 14.3 2.3 0.034 14.0 0.3 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3423 PF11903.3 CEH13756.1 - 0.1 12.3 0.8 0.49 10.1 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3423) Secretin_N_2 PF07655.8 CEH13757.1 - 3.5 8.0 7.3 13 6.2 0.0 2.7 3 0 0 3 3 3 0 Secretin N-terminal domain Form_Nir_trans PF01226.12 CEH13758.1 - 2.7e-60 203.3 20.4 3.6e-60 202.9 14.1 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter PAPS_reduct PF01507.14 CEH13760.1 - 5e-41 140.4 0.0 6.6e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF202 PF02656.10 CEH13763.1 - 3.7e-13 49.4 0.5 3.7e-13 49.4 0.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF202) vATP-synt_E PF01991.13 CEH13764.1 - 4.4e-58 195.8 16.3 5.1e-58 195.6 11.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Afaf PF15339.1 CEH13764.1 - 0.26 10.8 6.6 0.071 12.6 2.0 1.8 2 0 0 2 2 2 0 Acrosome formation-associated factor IncA PF04156.9 CEH13764.1 - 4 6.9 18.6 5.8 6.4 12.9 1.3 1 0 0 1 1 1 0 IncA protein Yippee-Mis18 PF03226.9 CEH13765.1 - 1.3e-21 76.4 0.0 2.2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1162 PF06650.7 CEH13766.1 - 2.8e-72 243.2 0.0 5.1e-69 232.5 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CEH13766.1 - 2.9e-40 136.4 0.1 7.5e-40 135.1 0.1 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 CEH13766.1 - 6.7e-05 22.9 0.0 0.00029 20.9 0.0 2.1 2 0 0 2 2 2 1 ATG C terminal domain Complex1_LYR_2 PF13233.1 CEH13766.1 - 0.096 13.1 4.1 0.43 11.0 1.4 2.9 3 0 0 3 3 3 0 Complex1_LYR-like TRAPPC-Trs85 PF12739.2 CEH13767.1 - 6.8e-93 311.5 0.2 1.2e-92 310.7 0.2 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Gryzun PF07919.7 CEH13767.1 - 1.1e-07 30.6 0.0 1.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi TRAPPC9-Trs120 PF08626.6 CEH13767.1 - 0.079 10.2 0.0 0.16 9.2 0.0 1.4 2 0 0 2 2 2 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF572 PF04502.8 CEH13768.1 - 0.00029 20.1 0.0 0.00049 19.4 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF572) Peptidase_C48 PF02902.14 CEH13769.1 - 7.3e-05 22.4 0.0 0.00082 19.0 0.0 2.0 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain CCD PF07860.6 CEH13769.1 - 0.01 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 WisP family C-Terminal Region GATA PF00320.22 CEH13770.1 - 4.8e-12 45.0 2.3 1.1e-11 43.9 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger RasGEF PF00617.14 CEH13771.1 - 6.5e-45 153.1 0.0 1e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEH13771.1 - 2.4e-06 27.5 0.0 5.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 CEH13771.1 - 4e-05 24.0 0.0 7.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CEH13771.1 - 0.014 14.7 0.1 0.035 13.4 0.1 1.7 1 1 0 1 1 1 0 Ras family AAA_17 PF13207.1 CEH13771.1 - 0.03 15.1 0.0 0.077 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CEH13771.1 - 0.052 13.4 0.0 0.052 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CEH13771.1 - 0.067 13.3 0.0 0.6 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CEH13771.1 - 0.07 12.8 0.2 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 CEH13771.1 - 0.19 10.5 0.0 0.37 9.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Arf PF00025.16 CEH13771.1 - 0.25 10.5 0.0 0.6 9.3 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family Pex24p PF06398.6 CEH13772.1 - 1.5e-29 102.9 2.8 5.4e-26 91.2 0.1 2.4 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin DUF3414 PF11894.3 CEH13773.1 - 1.8e-282 940.1 0.0 2.3e-282 939.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Glycos_transf_1 PF00534.15 CEH13774.1 - 2.2e-15 56.4 0.0 4.3e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CEH13774.1 - 3.1e-07 30.6 0.0 3.8e-06 27.0 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CEH13774.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 His_Phos_2 PF00328.17 CEH13776.1 - 1.7e-26 93.4 0.0 4.7e-26 91.9 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PHD PF00628.24 CEH13777.1 - 5e-14 51.7 17.6 3.4e-08 33.0 4.4 3.2 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 CEH13777.1 - 0.024 13.9 3.2 0.071 12.3 1.2 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 CEH13777.1 - 9.9 5.5 14.5 1.5 8.2 0.7 3.7 3 0 0 3 3 3 0 PHD-finger FA_desaturase PF00487.19 CEH13778.1 - 8.2e-25 87.7 17.9 1.2e-24 87.1 12.4 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Pkinase PF00069.20 CEH13779.1 - 4e-55 186.7 0.0 2.1e-54 184.4 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH13779.1 - 1.5e-26 93.0 0.0 3.6e-26 91.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RR_TM4-6 PF06459.7 CEH13779.1 - 0.94 9.3 9.2 1.7 8.4 6.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.10 CEH13779.1 - 1.8 7.7 6.6 3.7 6.7 4.6 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Borrelia_P83 PF05262.6 CEH13779.1 - 2.4 6.3 9.4 3.4 5.8 6.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ATP12 PF07542.6 CEH13780.1 - 1.6e-39 134.6 0.9 2.2e-39 134.1 0.0 1.7 2 0 0 2 2 2 1 ATP12 chaperone protein Nup96 PF12110.3 CEH13781.1 - 2.8e-85 285.9 0.2 3.9e-85 285.4 0.1 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 CEH13781.1 - 9.7e-37 125.9 0.0 1.9e-35 121.7 0.0 2.2 1 1 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CEH13781.1 - 8e-28 96.9 373.6 3.4e-09 36.9 28.1 12.1 5 2 6 11 11 11 7 Nucleoporin FG repeat region HLH PF00010.21 CEH13782.1 - 6.1e-09 35.4 0.4 1.6e-08 34.0 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Aconitase PF00330.15 CEH13783.1 - 7.1e-174 578.6 0.0 1.5e-173 577.6 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CEH13783.1 - 4.4e-43 146.5 0.0 7.2e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Velvet PF11754.3 CEH13785.1 - 3.7e-46 157.3 0.0 5.8e-32 110.9 0.0 2.4 2 0 0 2 2 2 2 Velvet factor FHA PF00498.21 CEH13786.1 - 3.6e-14 52.6 0.1 6.5e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 FHA domain Prefoldin_2 PF01920.15 CEH13786.1 - 0.041 13.6 6.6 0.29 10.8 0.9 2.8 2 1 0 2 2 2 0 Prefoldin subunit Spc7 PF08317.6 CEH13786.1 - 0.059 12.0 0.4 0.22 10.1 0.0 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.7 CEH13786.1 - 0.099 12.4 1.4 2.2 8.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 CEH13786.1 - 0.12 12.1 9.4 1.1 9.0 0.8 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 CEH13786.1 - 0.15 11.8 0.1 0.15 11.8 0.1 3.1 3 1 1 4 4 4 0 Homeobox associated leucine zipper DUF972 PF06156.8 CEH13786.1 - 0.15 12.3 2.4 15 5.9 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) TBPIP PF07106.8 CEH13786.1 - 0.24 10.9 1.6 0.5 9.8 0.3 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 CEH13786.1 - 0.75 9.6 12.0 0.16 11.8 0.8 3.1 2 1 0 3 3 3 0 Tropomyosin like Filament PF00038.16 CEH13786.1 - 0.97 8.8 6.6 4.6 6.6 0.1 2.8 2 1 0 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 CEH13786.1 - 1.4 8.8 12.2 0.67 9.8 0.7 3.0 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spectrin PF00435.16 CEH13786.1 - 1.5 9.1 8.9 3.2 8.0 0.3 3.0 2 1 0 2 2 2 0 Spectrin repeat CENP-Q PF13094.1 CEH13786.1 - 2.3 8.2 11.4 1.1 9.2 0.3 3.4 2 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 CEH13786.1 - 3.4 7.5 11.1 4.1 7.2 1.7 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.15 CEH13786.1 - 5.9 5.9 11.7 1.2 8.1 1.6 2.6 2 1 1 3 3 3 0 Tropomyosin GATA PF00320.22 CEH13787.1 - 2.3e-27 94.0 13.7 1.5e-14 53.0 2.0 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 CEH13787.1 - 2.8e-06 26.7 0.1 6.3e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GET2 PF08690.5 CEH13787.1 - 7.7e-05 22.0 0.6 0.00013 21.2 0.4 1.3 1 0 0 1 1 1 1 GET complex subunit GET2 DUF2387 PF09526.5 CEH13787.1 - 0.0096 15.8 0.5 0.85 9.5 0.0 2.6 2 0 0 2 2 2 1 Probable metal-binding protein (DUF2387) eIF-5_eIF-2B PF01873.12 CEH13787.1 - 0.036 13.7 3.9 0.29 10.7 0.3 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.5 CEH13787.1 - 0.075 12.9 0.9 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 CEH13787.1 - 0.11 11.8 2.9 7.4 5.9 0.3 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Elf1 PF05129.8 CEH13787.1 - 0.27 10.9 0.9 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 CEH13787.1 - 0.45 10.3 5.2 11 5.8 0.3 2.8 1 1 1 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 CEH13787.1 - 0.78 9.2 4.7 3.9 7.0 0.3 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit RRN7 PF11781.3 CEH13787.1 - 0.81 9.2 5.3 3.8 7.1 0.2 2.8 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 UCR_hinge PF02320.11 CEH13788.1 - 2.7e-19 68.8 4.8 6.3e-19 67.6 3.3 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF2146 PF10220.4 CEH13788.1 - 0.81 7.5 5.9 0.76 7.6 4.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Tmemb_cc2 PF10267.4 CEH13788.1 - 1.3 7.5 8.3 13 4.2 6.8 1.7 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Sigma70_ner PF04546.8 CEH13788.1 - 1.6 8.3 7.9 1.9 8.0 5.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.7 CEH13788.1 - 2.5 7.2 12.0 2.8 7.1 8.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 CEH13788.1 - 4.1 5.3 8.1 4.5 5.1 5.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CEH13788.1 - 7.3 4.9 17.6 7.4 4.9 12.2 1.0 1 0 0 1 1 1 0 Daxx Family Ribosomal_L13 PF00572.13 CEH13790.1 - 7.4e-44 148.8 0.3 8.8e-44 148.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 AMP-binding PF00501.23 CEH13792.1 - 6.5e-70 235.6 0.0 9e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 CEH13792.1 - 3.5e-10 38.9 0.4 0.00019 20.8 0.0 5.4 5 0 0 5 5 5 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.1 CEH13792.1 - 1.5e-07 32.2 0.0 4.1e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.1 CEH13792.1 - 4.9e-06 25.9 11.7 6.2e-05 22.4 0.2 4.3 5 1 0 5 5 5 2 Hexapeptide repeat of succinyl-transferase PP-binding PF00550.20 CEH13792.1 - 0.00012 22.2 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site BPL_N PF09825.4 CEH13794.1 - 9.3e-08 31.2 0.1 4.6e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal PDEase_I PF00233.14 CEH13795.1 - 9.7e-25 87.6 0.0 1.2e-11 44.8 0.0 3.1 2 1 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Glycogen_syn PF05693.8 CEH13797.1 - 0 1117.4 0.0 0 1117.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.6 CEH13797.1 - 8e-08 32.0 0.1 7.6e-07 28.8 0.1 2.4 1 1 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 CEH13797.1 - 3.3e-07 29.8 0.0 0.00011 21.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CEH13797.1 - 2e-06 28.0 0.1 5.6e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain SPO22 PF08631.5 CEH13798.1 - 7.1e-12 44.9 0.2 2e-10 40.2 0.0 2.5 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like 2-oxoacid_dh PF00198.18 CEH13799.1 - 3e-79 265.5 0.0 4.4e-79 264.9 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CEH13799.1 - 2.4e-19 68.7 1.2 4.3e-19 67.9 0.8 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme TFIIF_alpha PF05793.7 CEH13799.1 - 0.0022 16.4 26.9 0.0029 16.0 18.6 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HlyD_3 PF13437.1 CEH13799.1 - 0.0051 17.1 0.3 0.2 12.0 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 CEH13799.1 - 0.0069 16.0 0.0 0.0069 16.0 0.0 3.0 2 1 1 3 3 2 1 Biotin-lipoyl like HlyD PF00529.15 CEH13799.1 - 0.02 14.1 14.9 0.04 13.2 10.3 1.5 1 0 0 1 1 1 0 HlyD family secretion protein Daxx PF03344.10 CEH13799.1 - 0.08 11.4 21.6 0.11 10.9 15.0 1.1 1 0 0 1 1 1 0 Daxx Family MIP-T3 PF10243.4 CEH13799.1 - 0.12 10.8 32.8 0.16 10.3 22.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 CEH13799.1 - 0.15 10.0 17.7 0.19 9.6 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 CEH13799.1 - 0.22 10.9 22.1 0.42 10.0 15.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 CEH13799.1 - 0.36 8.5 15.3 0.46 8.1 10.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 CEH13799.1 - 0.54 9.5 27.0 0.85 8.9 18.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNase_H2-Ydr279 PF09468.5 CEH13799.1 - 1.3 8.1 11.6 2.4 7.2 8.0 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Borrelia_P83 PF05262.6 CEH13799.1 - 1.3 7.1 18.6 1.8 6.7 12.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DHHW PF14286.1 CEH13799.1 - 2.2 7.5 12.6 3.1 7.0 8.7 1.3 1 0 0 1 1 1 0 DHHW protein Zip PF02535.17 CEH13799.1 - 2.7 6.8 7.0 3.9 6.3 4.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 CEH13799.1 - 4.7 7.0 27.2 7.9 6.2 18.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.11 CEH13799.1 - 6.1 6.6 9.8 9.8 5.9 6.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 CEH13799.1 - 6.1 5.5 16.8 9.6 4.9 11.7 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Nop14 PF04147.7 CEH13799.1 - 7.2 4.3 27.3 10 3.9 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 CEH13799.1 - 9.1 3.8 14.6 11 3.5 10.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MARVEL PF01284.18 CEH13800.1 - 0.0011 18.7 14.5 0.0011 18.7 9.1 1.7 1 1 1 2 2 2 1 Membrane-associating domain Scaffolding_pro PF11418.3 CEH13804.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Phi29 scaffolding protein CusF_Ec PF11604.3 CEH13805.1 - 0.03 14.1 0.0 2.7 7.9 0.0 2.8 3 0 0 3 3 3 0 Copper binding periplasmic protein CusF PPR_2 PF13041.1 CEH13806.1 - 9.9e-16 57.4 0.0 0.0023 17.8 0.0 7.6 6 2 2 8 8 8 4 PPR repeat family PPR_3 PF13812.1 CEH13806.1 - 3.1e-14 51.9 11.1 0.00011 22.1 0.1 9.1 10 1 0 10 10 10 3 Pentatricopeptide repeat domain PPR PF01535.15 CEH13806.1 - 4.7e-14 51.2 2.7 7.5e-05 22.4 0.0 6.4 5 1 0 5 5 5 3 PPR repeat PPR_1 PF12854.2 CEH13806.1 - 1e-13 50.5 2.6 9.4e-06 25.0 0.0 5.8 5 1 0 5 5 5 3 PPR repeat Sec34 PF04136.10 CEH13807.1 - 4.3e-19 68.7 0.0 1.4e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Sec34-like family Exo70 PF03081.10 CEH13807.1 - 0.048 12.4 1.2 0.45 9.2 0.1 2.5 2 0 0 2 2 2 0 Exo70 exocyst complex subunit DEAD PF00270.24 CEH13808.1 - 4.1e-33 114.2 0.0 4.9e-32 110.7 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH13808.1 - 1e-20 73.3 0.0 2.5e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH13808.1 - 2.3e-10 40.6 0.0 6.3e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CEH13808.1 - 0.00041 20.0 0.2 0.00041 20.0 0.2 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CEH13808.1 - 0.0023 18.0 0.4 0.21 11.7 0.3 2.7 1 1 0 1 1 1 1 AAA domain RAP1 PF07218.6 CEH13808.1 - 4.9 5.1 11.8 7.4 4.5 8.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ubiquitin PF00240.18 CEH13809.1 - 8.2e-35 118.0 0.7 1.4e-34 117.3 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 CEH13809.1 - 1.1e-22 79.6 0.3 2.2e-22 78.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CEH13809.1 - 8.8e-20 70.1 0.7 1.5e-19 69.4 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEH13809.1 - 1.3e-05 25.3 0.1 4.8e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 CEH13809.1 - 3.2e-05 23.7 0.4 0.00091 19.0 0.4 2.3 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 CEH13809.1 - 0.00021 21.0 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 CEH13809.1 - 0.0048 17.0 0.4 0.0065 16.6 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2207 PF09972.4 CEH13809.1 - 0.023 13.2 0.3 0.025 13.1 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) IBR PF01485.16 CEH13809.1 - 0.052 13.4 0.6 0.081 12.8 0.4 1.4 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 CEH13809.1 - 0.073 13.1 0.2 0.16 11.9 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 CEH13809.1 - 0.077 11.3 2.7 0.94 7.7 0.1 2.0 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Cucumo_2B PF03263.8 CEH13809.1 - 0.1 12.9 0.1 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Cucumovirus protein 2B TrbC PF04956.8 CEH13810.1 - 6.4 6.8 8.4 0.83 9.7 2.2 2.4 2 1 1 3 3 3 0 TrbC/VIRB2 family Metallophos PF00149.23 CEH13811.1 - 2.2e-29 102.2 0.1 3.8e-27 95.0 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Chromo PF00385.19 CEH13813.1 - 5.1e-09 35.6 0.4 1.4e-08 34.2 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DASH_Dad4 PF08650.5 CEH13814.1 - 1.5e-20 72.8 0.9 1.7e-20 72.6 0.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 CEH13814.1 - 0.024 14.3 0.1 0.032 13.9 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 tRNA-synt_2b PF00587.20 CEH13815.1 - 2.3e-34 118.4 0.0 4.6e-34 117.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CEH13815.1 - 8.8e-15 54.6 4.1 1.7e-14 53.7 2.8 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF2748 PF10871.3 CEH13815.1 - 0.081 11.3 0.1 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) COG2 PF06148.6 CEH13815.1 - 0.17 11.7 1.1 0.43 10.4 0.8 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Kdo PF06293.9 CEH13816.1 - 0.01 14.9 0.1 0.019 14.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Reo_sigmaC PF04582.7 CEH13817.1 - 0.005 16.0 4.2 0.005 16.0 2.9 5.1 2 2 2 5 5 5 3 Reovirus sigma C capsid protein SlyX PF04102.7 CEH13817.1 - 0.0064 16.8 3.4 0.0064 16.8 2.4 9.7 7 4 4 11 11 11 1 SlyX BCDHK_Adom3 PF10436.4 CEH13817.1 - 2.3 7.7 11.4 7.9 5.9 4.1 3.6 2 2 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase GWT1 PF06423.7 CEH13819.1 - 2.8e-24 85.7 0.1 7.4e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 GWT1 Ligase_CoA PF00549.14 CEH13820.1 - 5.2e-12 45.6 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 CEH13820.1 - 8.9e-07 29.3 0.4 2.1e-06 28.1 0.3 1.7 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.1 CEH13820.1 - 3.3e-06 26.7 0.0 1e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain MFS_1 PF07690.11 CEH13823.1 - 9.3e-37 126.5 41.4 9.3e-37 126.5 28.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH13823.1 - 7e-14 51.2 13.5 7e-14 51.2 9.4 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 CEH13823.1 - 4.4e-06 25.1 6.4 7.9e-06 24.3 4.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 CEH13823.1 - 2.4 6.0 9.6 0.082 10.9 0.7 2.8 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Arc PF03869.9 CEH13824.1 - 0.09 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Arc-like DNA binding domain IKI3 PF04762.7 CEH13826.1 - 1.6e-192 641.8 0.0 3.1e-190 634.2 0.0 2.7 1 1 0 1 1 1 1 IKI3 family tRNA-synt_2 PF00152.15 CEH13828.1 - 2.1e-89 299.6 0.0 8.5e-89 297.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 CEH13828.1 - 0.00046 19.8 0.0 0.032 13.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 CEH13828.1 - 0.028 13.6 0.1 0.64 9.1 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) EHN PF06441.7 CEH13829.1 - 1.1e-30 105.8 5.6 7.7e-23 80.5 0.3 2.4 1 1 1 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CEH13829.1 - 1.1e-05 25.4 0.3 1.8e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH13829.1 - 0.00085 18.9 0.1 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold RNA_lig_T4_1 PF09511.5 CEH13830.1 - 2.4e-66 223.4 0.0 4.2e-66 222.5 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 CEH13830.1 - 2.8e-22 79.3 0.3 2.7e-08 33.8 0.1 3.5 2 1 1 3 3 3 3 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 CEH13830.1 - 3.7e-14 52.5 0.1 1.8e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 Fungal tRNA ligase phosphodiesterase domain KTI12 PF08433.5 CEH13830.1 - 0.0024 17.1 0.0 0.0044 16.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 CEH13830.1 - 0.0075 16.1 0.3 0.06 13.2 0.0 2.4 1 1 0 2 2 2 1 AAA domain 2_5_RNA_ligase2 PF13563.1 CEH13830.1 - 0.31 10.7 5.7 6.7 6.4 0.4 3.0 3 1 0 3 3 3 0 2'-5' RNA ligase superfamily HSP20 PF00011.16 CEH13831.1 - 2.4e-20 72.2 0.5 2.5e-19 69.0 0.3 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Epiglycanin_C PF14654.1 CEH13831.1 - 0.03 14.3 0.1 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region LTV PF04180.9 CEH13832.1 - 2.3e-45 155.8 40.0 2e-35 123.1 3.4 5.6 4 2 1 5 5 5 4 Low temperature viability protein Crinivirus_P26 PF07416.6 CEH13832.1 - 0.19 11.1 0.0 21 4.5 0.0 2.2 2 0 0 2 2 2 0 Crinivirus P26 protein HAP1_N PF04849.8 CEH13833.1 - 0.00018 20.5 0.3 0.00018 20.5 0.2 2.9 2 1 1 3 3 3 1 HAP1 N-terminal conserved region Filament PF00038.16 CEH13833.1 - 0.024 14.1 7.5 0.017 14.5 2.8 2.1 2 0 0 2 2 2 0 Intermediate filament protein ATP-synt_D PF01813.12 CEH13833.1 - 0.39 10.2 6.4 0.061 12.8 0.9 2.1 2 0 0 2 2 2 0 ATP synthase subunit D TMF_DNA_bd PF12329.3 CEH13833.1 - 0.96 9.2 10.1 4.6 7.1 4.4 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FemAB PF02388.11 CEH13833.1 - 1.4 7.5 3.4 2.2 6.8 2.4 1.2 1 0 0 1 1 1 0 FemAB family IncA PF04156.9 CEH13833.1 - 1.6 8.2 10.4 0.9 9.0 4.5 2.2 1 1 1 2 2 2 0 IncA protein DivIC PF04977.10 CEH13833.1 - 9.9 5.7 13.2 2 7.9 0.1 3.5 2 1 1 3 3 3 0 Septum formation initiator RRM_1 PF00076.17 CEH13834.1 - 3.7e-30 103.3 2.7 7e-18 64.0 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH13834.1 - 9.7e-24 83.1 0.1 3.4e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH13834.1 - 3e-06 26.9 0.0 0.00011 21.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 CEH13834.1 - 0.01 14.4 3.0 0.018 13.5 2.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-LYAR PF08790.6 CEH13836.1 - 1.6e-11 43.6 0.2 3e-11 42.8 0.2 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger G-patch PF01585.18 CEH13836.1 - 6.1e-06 25.9 2.5 2e-05 24.2 1.7 1.9 1 0 0 1 1 1 1 G-patch domain DUF3133 PF11331.3 CEH13836.1 - 0.088 12.3 1.0 0.23 11.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) Epimerase PF01370.16 CEH13837.1 - 1.4e-37 129.3 0.0 1.8e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CEH13837.1 - 6.2e-26 90.1 0.0 1e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CEH13837.1 - 2.2e-14 52.8 0.0 8.8e-14 50.8 0.0 1.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CEH13837.1 - 9.3e-09 34.5 0.5 2.1e-08 33.4 0.3 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CEH13837.1 - 1.3e-08 34.1 0.0 8.4e-08 31.4 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 CEH13837.1 - 1.6e-07 30.5 0.0 2.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CEH13837.1 - 7.2e-05 22.8 0.1 0.0028 17.7 0.0 2.4 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 CEH13837.1 - 0.00074 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH13837.1 - 0.046 13.3 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 KR domain NmrA PF05368.8 CEH13837.1 - 0.064 12.4 0.2 0.36 10.0 0.0 2.3 2 1 0 2 2 2 0 NmrA-like family Acetyltransf_1 PF00583.19 CEH13838.1 - 1.5e-13 50.5 0.1 2.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CEH13838.1 - 1.3e-07 31.2 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CEH13838.1 - 6.2e-06 26.2 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEH13838.1 - 2.9e-05 24.1 0.0 5.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CEH13838.1 - 0.00028 20.8 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEH13838.1 - 0.0075 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Autophagy_act_C PF03987.10 CEH13839.1 - 1.6e-07 31.3 0.0 4.7e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain NMT1 PF09084.6 CEH13839.1 - 0.0014 18.2 0.1 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like CRM1_C PF08767.6 CEH13840.1 - 2.2e-116 388.2 0.0 2.2e-116 388.2 0.0 3.2 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 CEH13840.1 - 2.9e-39 134.3 5.4 2.9e-39 134.3 3.7 3.4 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 CEH13840.1 - 1.5e-12 47.2 2.6 4.8e-12 45.6 1.2 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Ank_2 PF12796.2 CEH13842.1 - 2.3e-42 143.2 2.5 7.2e-17 61.5 0.0 4.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CEH13842.1 - 2.6e-37 124.7 5.9 5.3e-07 29.1 0.0 7.9 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 CEH13842.1 - 8.3e-34 115.3 0.5 7.7e-10 39.0 0.0 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.14 CEH13842.1 - 1.9e-33 116.4 1.2 4.7e-19 69.2 0.0 2.6 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.1 CEH13842.1 - 1.2e-23 82.5 7.1 7.1e-05 22.9 0.0 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH13842.1 - 2.9e-22 76.5 1.9 0.0053 16.8 0.0 7.9 7 0 0 7 7 7 5 Ankyrin repeat GDPD PF03009.12 CEH13842.1 - 3.7e-10 39.7 0.0 3.4e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RFX_DNA_binding PF02257.10 CEH13843.1 - 1.3e-13 50.8 0.0 3.2e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 RFX DNA-binding domain DUF4231 PF14015.1 CEH13850.1 - 0.28 11.1 0.1 0.28 11.1 0.1 3.1 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) V-SNARE PF05008.10 CEH13851.1 - 9.8e-17 60.8 11.3 1.1e-16 60.7 2.1 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 CEH13851.1 - 9.1e-16 57.6 7.7 9.1e-16 57.6 5.4 3.3 4 1 1 5 5 5 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CEH13851.1 - 0.00097 18.7 0.3 0.0023 17.5 0.2 1.7 1 0 0 1 1 1 1 Sec20 Prominin PF05478.6 CEH13851.1 - 0.0017 16.0 0.9 0.0033 15.0 0.6 1.7 1 1 0 1 1 1 1 Prominin THOC7 PF05615.8 CEH13851.1 - 0.018 15.3 1.4 0.27 11.4 0.1 2.4 2 1 0 2 2 2 0 Tho complex subunit 7 CENP-F_leu_zip PF10473.4 CEH13851.1 - 0.028 14.2 9.8 0.052 13.4 1.9 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec8_exocyst PF04048.9 CEH13851.1 - 0.043 13.4 1.7 0.89 9.1 0.3 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ApoLp-III PF07464.6 CEH13851.1 - 0.054 13.5 6.1 0.12 12.3 0.3 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ODV-E18 PF10717.4 CEH13851.1 - 0.069 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 OppC_N PF12911.2 CEH13851.1 - 0.13 11.6 0.4 0.24 10.7 0.3 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF883 PF05957.8 CEH13851.1 - 0.33 11.3 12.2 0.75 10.2 0.4 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Sigma_reg_N PF13800.1 CEH13851.1 - 0.39 10.7 1.5 0.61 10.1 1.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal YqjK PF13997.1 CEH13851.1 - 1.7 8.8 8.2 0.26 11.4 1.3 2.4 2 0 0 2 2 2 0 YqjK-like protein WXG100 PF06013.7 CEH13851.1 - 3.5 7.6 15.5 1.3 9.0 0.8 4.7 3 1 2 5 5 5 0 Proteins of 100 residues with WXG COG2 PF06148.6 CEH13851.1 - 4.5 7.1 6.0 1.7 8.4 0.6 2.6 2 2 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RNA_pol_Rpb1_5 PF04998.12 CEH13852.1 - 1.2e-84 283.8 0.0 1.8e-84 283.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CEH13852.1 - 8.4e-60 201.4 0.0 1.5e-59 200.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CEH13852.1 - 3.1e-36 124.4 0.0 5.7e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 CEH13852.1 - 2.7e-24 86.0 0.1 5.1e-20 72.0 0.1 3.2 4 0 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 CEH13852.1 - 3.3e-22 78.2 0.0 8.9e-22 76.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Cwf_Cwc_15 PF04889.7 CEH13852.1 - 0.013 15.1 13.2 0.045 13.4 9.1 1.9 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ceramidase PF05875.7 CEH13853.1 - 6.7e-73 245.0 1.1 8e-73 244.7 0.7 1.0 1 0 0 1 1 1 1 Ceramidase Macoilin PF09726.4 CEH13853.1 - 2.6 6.2 5.1 3.5 5.7 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DnaJ-X PF14308.1 CEH13854.1 - 1.7e-60 203.8 0.7 1.7e-60 203.8 0.5 1.9 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CEH13854.1 - 3.1e-21 74.8 0.3 7.6e-21 73.6 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain Ank PF00023.25 CEH13855.1 - 9.2e-10 37.8 0.1 0.00029 20.4 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CEH13855.1 - 9.3e-10 38.7 2.0 3.2e-06 27.4 0.3 3.1 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CEH13855.1 - 9.4e-09 35.4 0.3 5.4e-07 29.8 0.2 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CEH13855.1 - 5.5e-08 32.3 0.3 0.00085 19.3 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CEH13855.1 - 1.7e-05 24.9 1.4 0.00078 19.6 0.4 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Josephin PF02099.12 CEH13855.1 - 0.08 12.5 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Josephin Sds3 PF08598.6 CEH13856.1 - 6.2e-26 91.2 5.1 2.1e-25 89.4 3.5 1.9 1 0 0 1 1 1 1 Sds3-like Spindle_Spc25 PF08234.7 CEH13858.1 - 1.8e-11 43.8 0.0 4.4e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 TMCO5 PF14992.1 CEH13858.1 - 0.11 11.5 14.6 0.18 10.9 10.2 1.2 1 0 0 1 1 1 0 TMCO5 family APG6 PF04111.7 CEH13858.1 - 0.12 11.3 13.2 0.18 10.7 9.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 CEH13858.1 - 0.33 11.0 7.0 0.11 12.6 2.3 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 CEH13858.1 - 0.62 7.8 7.3 0.77 7.5 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Transformer PF06495.6 CEH13858.1 - 3 7.7 5.3 5.3 6.8 3.6 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein Ribonuc_red_sm PF00268.16 CEH13859.1 - 1.6e-116 388.2 2.6 1.9e-116 387.9 1.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SPC12 PF06645.8 CEH13860.1 - 5.3e-25 87.0 0.1 6.8e-25 86.6 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ExoD PF06055.7 CEH13860.1 - 0.012 14.7 1.1 0.051 12.6 0.7 1.8 1 1 0 1 1 1 0 Exopolysaccharide synthesis, ExoD NmrA PF05368.8 CEH13861.1 - 1.1e-31 109.9 0.3 2.1e-31 109.0 0.3 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CEH13861.1 - 8.2e-07 29.2 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Bacteriocin_IId PF09221.5 CEH13861.1 - 1.2 9.0 3.6 3.1 7.7 1.5 2.2 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Mito_carr PF00153.22 CEH13862.1 - 1.7e-59 197.5 10.8 1.6e-23 82.2 0.0 5.1 3 1 0 3 3 3 3 Mitochondrial carrier protein RIX1 PF08167.7 CEH13864.1 - 0.00061 19.5 0.9 0.0027 17.3 0.1 2.5 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Brix PF04427.13 CEH13866.1 - 1.9e-44 151.5 0.1 2.5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain EAP30 PF04157.11 CEH13867.1 - 3e-31 108.3 0.0 4.8e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CEH13867.1 - 8.6e-11 41.5 0.0 2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 CEH13867.1 - 0.0019 17.2 7.7 0.074 12.1 0.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 CEH13867.1 - 0.075 12.8 6.0 0.29 10.9 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 CEH13867.1 - 0.24 11.0 10.4 0.48 10.0 0.1 3.0 2 2 1 3 3 3 0 Sec23/Sec24 zinc finger GCC2_GCC3 PF07699.8 CEH13867.1 - 7.9 6.1 7.0 14 5.3 0.7 2.6 2 0 0 2 2 2 0 GCC2 and GCC3 Rad21_Rec8_N PF04825.8 CEH13868.1 - 4.9e-40 135.9 0.0 7.4e-40 135.3 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CEH13868.1 - 3.6e-14 51.6 0.0 7.4e-14 50.6 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CEH13868.1 - 0.00013 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 ScpA/B protein Ribosomal_S5 PF00333.15 CEH13869.1 - 3.5e-12 45.8 1.0 8.4e-12 44.6 0.7 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CEH13869.1 - 1e-11 43.9 0.0 2.8e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain ParA PF10609.4 CEH13870.1 - 1.9e-33 114.1 0.0 3.1e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CEH13870.1 - 5.6e-05 22.6 0.0 7.5e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Polyketide_cyc PF03364.15 CEH13871.1 - 4.2e-24 85.0 0.0 5.2e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 CEH13871.1 - 9.6e-09 35.5 0.0 1.3e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_15 PF09445.5 CEH13872.1 - 4.8e-14 52.2 0.0 9.6e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Dam PF05869.6 CEH13872.1 - 0.093 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Glyco_hydro_88 PF07470.8 CEH13876.1 - 1.8e-12 46.9 0.2 3e-12 46.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Methyltransf_23 PF13489.1 CEH13877.1 - 1.3e-09 38.0 0.1 2.8e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH13877.1 - 2.2e-09 37.6 0.2 1.4e-08 35.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH13877.1 - 0.00024 21.1 0.0 0.0026 17.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH13877.1 - 0.00027 21.5 0.0 0.00063 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH13877.1 - 0.00031 20.3 0.0 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH13877.1 - 0.00081 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEH13877.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CEH13877.1 - 0.0045 17.4 0.0 0.012 16.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CEH13877.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DPM2 PF07297.7 CEH13879.1 - 3.4e-25 88.1 0.2 4e-25 87.9 0.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 CEH13879.1 - 7.2e-06 25.6 0.3 8.3e-06 25.4 0.2 1.1 1 0 0 1 1 1 1 PIG-P DUF1206 PF06724.6 CEH13879.1 - 0.066 12.9 4.4 0.21 11.3 1.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF3995 PF13160.1 CEH13879.1 - 0.19 11.7 2.6 2.1 8.3 1.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3995) PCP_red PF08369.5 CEH13879.1 - 0.21 11.4 1.8 0.39 10.6 1.2 1.4 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit TatC PF00902.13 CEH13879.1 - 0.6 9.4 4.7 0.81 9.0 3.3 1.4 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF1469 PF07332.6 CEH13879.1 - 0.62 9.8 5.8 1.6 8.5 4.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) TPP_enzyme_N PF02776.13 CEH13880.1 - 1.9e-55 186.9 0.0 4.5e-55 185.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CEH13880.1 - 3.7e-45 153.2 0.0 1.2e-43 148.3 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CEH13880.1 - 2.1e-40 137.6 0.6 2e-39 134.4 0.1 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 CEH13880.1 - 0.043 13.3 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Tubulin PF00091.20 CEH13881.1 - 3e-68 229.8 0.0 4.2e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CEH13881.1 - 2.3e-47 160.1 0.0 3.4e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CEH13881.1 - 0.00028 20.3 0.0 0.00075 19.0 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain SAP18 PF06487.7 CEH13883.1 - 3.9e-16 58.9 0.0 6.3e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Vps16_N PF04841.8 CEH13884.1 - 1.5e-73 247.6 0.0 1.1e-49 169.1 0.0 2.4 3 0 0 3 3 3 2 Vps16, N-terminal region Vps16_C PF04840.7 CEH13884.1 - 2.8e-57 194.0 0.4 1.1e-31 110.0 0.0 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region DEAD PF00270.24 CEH13885.1 - 4.2e-35 120.7 0.0 9.5e-34 116.3 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH13885.1 - 1.2e-18 66.7 0.0 2.5e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CEH13885.1 - 3.2e-17 61.8 0.2 7.9e-17 60.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CEH13885.1 - 0.00047 20.0 0.2 0.0016 18.2 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CEH13885.1 - 0.003 17.7 0.7 4.5 7.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain Prosystemin PF07376.6 CEH13885.1 - 0.035 13.4 2.4 0.062 12.6 1.7 1.3 1 0 0 1 1 1 0 Prosystemin HVSL PF09749.4 CEH13886.1 - 1.9e-19 69.6 0.0 2.8e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 CEH13886.1 - 0.00031 20.4 0.4 0.00077 19.2 0.1 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily RNA_pol_L_2 PF13656.1 CEH13887.1 - 9.1e-25 85.9 0.0 1.1e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CEH13887.1 - 7.7e-13 47.3 0.0 1.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L7Ae PF01248.21 CEH13888.1 - 2.3e-18 65.4 0.2 4.5e-18 64.5 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CEH13888.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 SUI1 PF01253.17 CEH13889.1 - 1.1e-29 102.0 1.1 1.5e-29 101.6 0.7 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 FKBP_N PF01346.13 CEH13889.1 - 0.2 11.7 5.5 0.2 11.7 0.2 2.0 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase PPTA PF01239.17 CEH13890.1 - 2.8e-31 105.5 13.1 1.4e-09 36.8 0.0 5.6 5 1 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.1 CEH13890.1 - 6.6 6.2 7.4 28 4.2 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) DUF3449 PF11931.3 CEH13892.1 - 1.9e-70 236.3 0.1 1.7e-69 233.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.2 CEH13892.1 - 8.3e-10 38.5 1.7 8.6e-07 28.9 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEH13892.1 - 3.7e-09 36.4 3.5 4.6e-06 26.6 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.3 CEH13892.1 - 7.4e-07 28.5 0.9 7.4e-07 28.5 0.6 2.0 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-DBF PF07535.7 CEH13892.1 - 0.0005 19.6 1.2 0.013 15.1 0.0 2.5 2 0 0 2 2 2 1 DBF zinc finger zf-C2H2_2 PF12756.2 CEH13892.1 - 0.05 13.7 0.1 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CEH13892.1 - 2.8 8.4 5.0 20 5.7 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type RRN3 PF05327.6 CEH13893.1 - 1.1e-137 459.5 0.0 1.6e-137 458.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Ribonuclease_3 PF00636.21 CEH13895.1 - 2.8e-05 24.5 0.0 7.5e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CEH13895.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease-III-like ATP-synt_J PF04911.7 CEH13898.1 - 1.9e-22 78.4 0.2 2e-22 78.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase j chain DEAD PF00270.24 CEH13899.1 - 2.8e-17 62.7 0.0 1.9e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CEH13899.1 - 5.6e-17 62.1 0.0 1.4e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CEH13899.1 - 5.1e-16 58.2 0.7 1.4e-15 56.8 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Cupin_2 PF07883.6 CEH13900.1 - 6.4e-10 38.4 0.1 1.3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CEH13900.1 - 0.081 12.6 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF1498 PF07385.7 CEH13900.1 - 0.13 11.4 0.1 0.24 10.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1498) Chs3p PF12271.3 CEH13901.1 - 1e-117 392.3 19.0 1.2e-117 392.0 13.1 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit NMT1 PF09084.6 CEH13903.1 - 2.1e-65 220.3 0.0 2.7e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 CEH13903.1 - 6.4e-07 29.0 1.2 3.3e-05 23.3 0.9 3.0 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.2 CEH13903.1 - 0.00057 19.3 0.0 0.00087 18.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.2 CEH13903.1 - 0.0018 17.2 0.0 0.013 14.4 0.0 2.0 1 1 1 2 2 2 1 PBP superfamily domain Tfb2 PF03849.9 CEH13904.1 - 1.3e-114 382.6 0.0 1.6e-114 382.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CEH13904.1 - 0.0042 16.8 0.0 0.0077 15.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_S7e PF01251.13 CEH13905.1 - 3.6e-50 170.1 5.0 8.5e-26 90.6 0.1 2.4 2 1 1 3 3 3 2 Ribosomal protein S7e RNA_pol_Rpb2_6 PF00562.23 CEH13906.1 - 2e-110 369.2 0.0 2.5e-110 368.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CEH13906.1 - 1.4e-30 105.7 0.0 2.2e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CEH13906.1 - 7.7e-24 83.2 0.0 9.1e-23 79.7 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 CEH13906.1 - 2.1e-23 82.0 0.0 4.4e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 CEH13906.1 - 6.6e-18 64.8 0.0 4.4e-17 62.1 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CEH13906.1 - 2.6e-14 53.2 0.0 2.4e-13 50.1 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 CEH13906.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ESCRT-II PF05871.7 CEH13907.1 - 2.2e-27 95.6 0.1 3.9e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 ESCRT-II complex subunit DUF605 PF04652.11 CEH13907.1 - 0.9 8.8 8.8 1.2 8.4 6.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF605 PF04652.11 CEH13908.1 - 2.4e-38 132.5 7.1 3.3e-38 132.0 4.9 1.1 1 0 0 1 1 1 1 Vta1 like Abhydrolase_6 PF12697.2 CEH13910.1 - 5.5e-11 42.7 2.7 9.3e-11 42.0 1.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH13910.1 - 2.5e-06 27.2 0.2 2.1e-05 24.2 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH13910.1 - 5.5e-05 22.9 0.3 0.00024 20.8 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cpn60_TCP1 PF00118.19 CEH13911.1 - 4.7e-137 457.5 8.2 8.8e-137 456.6 5.7 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Bim_N PF06773.6 CEH13912.1 - 0.074 12.8 0.7 4.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Bim protein N-terminus SpoIIIAH PF12685.2 CEH13912.1 - 0.095 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein RrnaAD PF00398.15 CEH13913.1 - 8.3e-54 182.3 0.0 1.1e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CEH13913.1 - 6.3e-10 39.1 0.0 1.6e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEH13913.1 - 0.0013 18.1 0.0 0.003 16.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CEH13913.1 - 0.0028 17.2 0.0 0.0067 16.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 CEH13913.1 - 0.0032 16.9 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_18 PF12847.2 CEH13913.1 - 0.0035 17.9 0.0 0.0057 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CEH13913.1 - 0.032 13.7 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 CEH13913.1 - 0.069 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CEH13913.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 CEH13913.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_28 PF02636.12 CEH13913.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DOT1 PF08123.8 CEH13913.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.10 CEH13914.1 - 2.4e-46 158.1 0.2 1.1e-23 83.9 0.3 3.0 2 1 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CEH13914.1 - 0.045 14.2 0.0 0.55 10.7 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain WD40 PF00400.27 CEH13915.1 - 3.6e-45 150.2 29.1 1.7e-10 40.3 0.1 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CEH13915.1 - 1.4e-27 96.4 0.0 2.6e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 CEH13915.1 - 0.0012 17.0 0.5 0.57 8.2 0.0 3.2 2 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.6 CEH13915.1 - 0.3 10.7 0.0 52 3.4 0.0 3.1 3 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A TAP42 PF04177.7 CEH13916.1 - 4e-54 183.8 0.0 5.6e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 TAP42-like family PCI PF01399.22 CEH13917.1 - 3.2e-12 46.6 0.1 7.3e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 PCI domain ubiquitin PF00240.18 CEH13918.1 - 9.8e-138 447.7 21.2 5.2e-34 115.4 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 CEH13918.1 - 6.7e-78 256.3 20.9 5.8e-19 67.5 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEH13918.1 - 1.6e-24 85.9 9.4 0.00017 21.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CEH13918.1 - 2.2e-21 76.2 0.7 0.0012 18.6 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CEH13918.1 - 3.6e-14 52.5 2.9 0.12 12.3 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CEH13918.1 - 1.1e-13 51.2 1.7 0.15 12.2 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CEH13918.1 - 1.1e-10 41.3 0.0 1.5 8.8 0.0 4.8 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 CEH13918.1 - 2e-07 30.6 4.9 3.5 7.4 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain Methyltrans_RNA PF04452.9 CEH13918.1 - 8.5e-07 28.3 0.6 1 8.4 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 CEH13918.1 - 3.1e-06 27.0 4.8 6.4 6.7 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG ACT_4 PF13291.1 CEH13918.1 - 0.00081 19.6 1.2 72 3.8 0.0 4.2 4 0 0 4 4 4 0 ACT domain Big_3_3 PF13750.1 CEH13918.1 - 0.0014 18.0 0.0 50 3.2 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 CEH13918.1 - 0.0033 15.8 13.1 3.9 5.6 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 CEH13918.1 - 0.012 15.6 5.3 65 3.7 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 CEH13918.1 - 0.022 14.6 13.9 8.8 6.3 0.2 4.6 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 CEH13918.1 - 0.027 14.4 29.1 3.5 7.7 1.2 4.3 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 CEH13918.1 - 0.044 13.7 7.0 53 3.9 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 CEH13918.1 - 1.4 9.0 12.6 86 3.2 0.1 5.8 4 4 0 4 4 4 0 FERM N-terminal domain CDC48_2 PF02933.12 CEH13918.1 - 1.6 8.4 13.0 40 3.9 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 DUF3781 PF12636.2 CEH13918.1 - 2.2 8.2 7.0 1.7e+02 2.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) MRP-L46 PF11788.3 CEH13919.1 - 3.3e-22 79.2 0.2 5.5e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Fe-S_biosyn PF01521.15 CEH13920.1 - 1.2e-18 67.1 0.0 1.7e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Macoilin PF09726.4 CEH13920.1 - 3.9 5.6 5.5 4.7 5.3 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein mRNA_triPase PF02940.10 CEH13922.1 - 2.2e-39 135.4 0.0 2.7e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain HSCB_C PF07743.8 CEH13923.1 - 4.4e-15 55.9 4.7 4.4e-15 55.9 3.2 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 CEH13923.1 - 5e-05 22.9 0.0 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain cwf21 PF08312.7 CEH13923.1 - 0.041 13.7 1.5 0.092 12.6 1.0 1.8 1 1 0 1 1 1 0 cwf21 domain FCD PF07729.7 CEH13923.1 - 0.046 14.0 1.4 1.5 9.1 0.3 2.2 2 0 0 2 2 2 0 FCD domain 4HBT_2 PF13279.1 CEH13926.1 - 1.7e-11 44.6 0.0 2.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Phosphodiest PF01663.17 CEH13927.1 - 1.2e-47 162.9 0.0 2e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HAD_2 PF13419.1 CEH13927.1 - 0.00074 19.7 0.7 2.2 8.4 0.0 3.2 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEH13927.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Mito_carr PF00153.22 CEH13928.1 - 8e-48 160.1 7.5 1.2e-15 56.9 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Cyclin_N PF00134.18 CEH13930.1 - 1.9e-05 24.2 0.0 3.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Zn_clus PF00172.13 CEH13932.1 - 1.3e-05 25.0 8.9 2.1e-05 24.3 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PFL PF02901.10 CEH13935.1 - 0.15 10.4 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase TAF8_C PF10406.4 CEH13936.1 - 9.5e-10 38.3 0.4 2.5e-09 37.0 0.2 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 CEH13936.1 - 0.037 13.7 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated DIM PF08194.7 CEH13938.1 - 0.065 13.1 0.4 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 DIM protein PNGaseA PF12222.3 CEH13939.1 - 1.9e-57 195.0 0.3 4.8e-57 193.7 0.2 1.6 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Ada3 PF10198.4 CEH13940.1 - 1.3e-22 79.9 0.0 2.9e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Pkinase PF00069.20 CEH13941.1 - 1.8e-67 227.2 0.0 2.3e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH13941.1 - 7.7e-50 169.3 0.0 1e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH13941.1 - 0.0013 17.7 0.0 0.0027 16.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 CEH13941.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) YIF1 PF03878.10 CEH13942.1 - 1.1e-79 267.0 0.3 1.4e-79 266.6 0.2 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 CEH13942.1 - 0.0059 16.1 8.5 0.013 14.9 5.9 1.7 1 1 0 1 1 1 1 Yip1 domain Pex14_N PF04695.8 CEH13942.1 - 0.062 13.3 1.9 0.21 11.6 1.3 2.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NTF2 PF02136.15 CEH13943.1 - 4.3e-28 98.0 0.0 7.2e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 CEH13943.1 - 0.00049 19.6 0.0 0.00086 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH13943.1 - 0.091 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Semialdhyde_dh PF01118.19 CEH13945.1 - 7e-06 26.3 0.0 1.5e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CEH13945.1 - 1.6e-05 24.9 0.1 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CEH13945.1 - 0.00021 20.2 0.0 0.013 14.4 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.16 CEH13945.1 - 0.00027 20.4 0.0 0.00033 20.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.11 CEH13945.1 - 0.0033 17.9 0.0 0.0055 17.2 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.14 CEH13945.1 - 0.034 12.8 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TIG PF01833.19 CEH13946.1 - 1e-12 47.8 5.2 1.4e-11 44.2 0.3 3.3 3 0 0 3 3 3 1 IPT/TIG domain Ank PF00023.25 CEH13946.1 - 6.9e-12 44.5 2.8 3.7e-05 23.3 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CEH13946.1 - 1.4e-11 44.6 0.1 3.1e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEH13946.1 - 1.2e-10 41.2 1.9 2.1e-09 37.2 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEH13946.1 - 3.4e-08 33.7 0.5 8.7e-08 32.4 0.3 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH13946.1 - 5.6e-07 29.1 0.8 0.035 14.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat LMBR1 PF04791.11 CEH13946.1 - 0.43 9.0 0.0 0.66 8.4 0.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Antimicrobial_5 PF08026.6 CEH13947.1 - 0.065 13.0 0.6 0.088 12.6 0.4 1.3 1 0 0 1 1 1 0 Bee antimicrobial peptide WD40 PF00400.27 CEH13948.1 - 1.4e-25 88.2 13.7 3.1e-09 36.3 0.0 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat PD40 PF07676.7 CEH13948.1 - 0.00041 19.9 0.1 0.08 12.6 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 CEH13948.1 - 0.12 12.0 0.1 28 4.3 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Cpn60_TCP1 PF00118.19 CEH13949.1 - 3.5e-148 494.2 0.5 4e-148 494.0 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LRR_4 PF12799.2 CEH13951.1 - 3.4e-36 122.2 37.7 7.1e-10 38.2 3.7 7.7 7 1 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEH13951.1 - 3.7e-25 87.4 40.2 7.9e-09 35.1 2.3 6.3 3 2 5 8 8 8 6 Leucine rich repeat LRR_9 PF14580.1 CEH13951.1 - 3e-14 52.9 6.2 6.2e-06 25.8 0.0 3.9 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.28 CEH13951.1 - 1.8e-09 36.3 36.6 0.12 12.4 0.0 11.2 12 1 1 13 13 13 5 Leucine Rich Repeat LRR_6 PF13516.1 CEH13951.1 - 3.9e-09 35.6 29.1 0.82 9.9 0.1 11.3 8 4 3 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 CEH13951.1 - 1.8e-07 30.1 26.5 0.86 10.0 0.0 10.9 11 1 0 11 11 11 2 Leucine rich repeat Rep_4 PF05797.6 CEH13951.1 - 0.17 10.6 1.2 0.31 9.6 0.8 1.4 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Aminotran_5 PF00266.14 CEH13952.1 - 3.5e-91 305.7 0.0 7e-91 304.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CEH13952.1 - 9.6e-06 24.9 0.1 1.5e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Peripla_BP_4 PF13407.1 CEH13952.1 - 0.02 14.2 0.0 0.98 8.7 0.0 2.3 2 0 0 2 2 2 0 Periplasmic binding protein domain Ribosomal_S24e PF01282.14 CEH13952.1 - 0.13 12.0 0.1 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S24e PHD PF00628.24 CEH13953.1 - 1.5e-06 27.8 4.5 2.3e-06 27.1 3.1 1.3 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 CEH13954.1 - 0.00048 20.4 0.0 0.00048 20.4 0.0 4.0 2 2 0 2 2 2 1 SET domain DctQ PF04290.7 CEH13955.1 - 0.0042 16.8 6.7 0.069 12.9 0.2 2.3 2 0 0 2 2 2 2 Tripartite ATP-independent periplasmic transporters, DctQ component 7TM_GPCR_Srd PF10317.4 CEH13955.1 - 0.0099 14.8 1.1 0.015 14.2 0.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Cation_ATPase_C PF00689.16 CEH13955.1 - 0.018 14.6 3.7 0.033 13.7 2.6 1.5 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF1705 PF08019.7 CEH13955.1 - 0.08 12.4 0.1 0.08 12.4 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1705) PsbJ PF01788.12 CEH13955.1 - 0.25 10.9 3.7 7.5 6.1 0.1 3.2 2 1 0 2 2 2 0 PsbJ Tetraspannin PF00335.15 CEH13955.1 - 0.56 9.4 7.2 1.5 8.0 5.0 1.7 1 1 0 1 1 1 0 Tetraspanin family RDD PF06271.7 CEH13955.1 - 1.7 8.5 7.4 0.36 10.7 1.0 2.1 2 0 0 2 2 2 0 RDD family ACPS PF01648.15 CEH13956.1 - 1.2e-10 41.2 0.0 2.9e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Cyclin PF08613.6 CEH13956.1 - 7.1e-09 36.2 0.0 7.1e-09 36.2 0.0 2.6 4 0 0 4 4 4 1 Cyclin BolA PF01722.13 CEH13957.1 - 1.1e-17 63.7 0.0 1.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein ResIII PF04851.10 CEH13958.1 - 1.7e-19 70.4 0.0 4.4e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CEH13958.1 - 1.7e-14 53.3 0.0 4e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEH13958.1 - 1.6e-13 50.4 0.0 3.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 CEH13958.1 - 0.00033 19.5 0.0 0.00061 18.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CEH13958.1 - 0.0017 18.5 0.0 0.004 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CEH13958.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 CEH13958.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 CEH13958.1 - 0.016 14.1 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 CEH13958.1 - 0.042 13.5 0.1 0.27 11.0 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 CEH13958.1 - 0.14 12.4 0.7 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Lipase_3 PF01764.20 CEH13960.1 - 5e-08 32.6 0.0 1.9e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CEH13960.1 - 0.054 13.2 0.1 0.18 11.5 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Romo1 PF10247.4 CEH13960.1 - 0.13 12.4 0.1 8.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 CSTF_C PF14304.1 CEH13961.1 - 0.16 11.2 0.2 0.92 8.8 0.0 1.9 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal SAM_decarbox PF01536.11 CEH13962.1 - 9.8e-76 254.5 0.0 5.4e-49 166.6 0.0 3.6 2 2 0 2 2 2 2 Adenosylmethionine decarboxylase DOPA_dioxygen PF08883.6 CEH13962.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Dopa 4,5-dioxygenase family Abhydrolase_4 PF08386.5 CEH13963.1 - 5.5e-11 42.2 0.0 2.8e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_5 PF12695.2 CEH13963.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family SR-25 PF10500.4 CEH13964.1 - 0.0076 15.7 3.9 0.016 14.7 2.7 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Nup54 PF13874.1 CEH13966.1 - 1.9e-24 85.9 4.7 4.8e-24 84.6 3.2 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Laminin_II PF06009.7 CEH13966.1 - 0.02 14.6 0.9 0.057 13.1 0.6 1.8 1 0 0 1 1 1 0 Laminin Domain II XPG_I PF00867.13 CEH13967.1 - 2.4e-16 59.5 0.0 1.3e-15 57.2 0.0 2.1 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CEH13967.1 - 0.00046 20.3 0.0 0.0014 18.8 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain EHN PF06441.7 CEH13968.1 - 2.5e-29 101.4 0.0 3.8e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CEH13968.1 - 1.9e-08 34.4 0.1 1.7e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Pkinase PF00069.20 CEH13969.1 - 4.5e-70 235.7 0.0 5.3e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH13969.1 - 1.2e-30 106.4 0.0 5.3e-30 104.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH13969.1 - 3.7e-06 26.1 0.1 1.1e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEH13969.1 - 0.00032 19.8 0.1 0.00057 19.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CEH13969.1 - 0.002 17.4 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CEH13969.1 - 0.0072 16.0 0.3 0.78 9.4 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-C2H2 PF00096.21 CEH13971.1 - 9.5e-06 25.6 3.4 0.025 14.9 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH13971.1 - 0.0034 17.6 3.4 0.43 11.0 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Tyr_Deacylase PF02580.11 CEH13972.1 - 1.7e-38 131.8 0.0 4e-25 88.4 0.0 2.1 2 0 0 2 2 2 2 D-Tyr-tRNA(Tyr) deacylase 4HBT PF03061.17 CEH13973.1 - 9.4e-17 60.9 1.6 2e-08 34.2 0.0 2.7 2 0 0 2 2 2 2 Thioesterase superfamily SET PF00856.23 CEH13974.1 - 0.0046 17.2 0.0 0.034 14.4 0.0 2.3 1 1 0 1 1 1 1 SET domain Spo7 PF03907.8 CEH13975.1 - 3.1e-17 62.8 0.3 3.1e-17 62.8 0.2 1.5 2 0 0 2 2 2 1 Spo7-like protein PPR_2 PF13041.1 CEH13977.1 - 1e-34 118.2 0.0 5.1e-11 42.3 0.0 7.1 8 0 0 8 8 8 4 PPR repeat family PPR PF01535.15 CEH13977.1 - 4.2e-30 101.6 0.5 2.2e-05 24.1 0.0 11.0 12 0 0 12 12 12 7 PPR repeat PPR_3 PF13812.1 CEH13977.1 - 6.8e-30 100.8 7.1 0.0011 19.0 0.0 11.6 11 0 0 11 11 11 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 CEH13977.1 - 7.9e-20 70.0 0.0 0.0014 18.0 0.0 8.2 8 0 0 8 8 8 6 PPR repeat TPR_16 PF13432.1 CEH13977.1 - 1.8e-06 28.4 20.7 0.0025 18.4 0.0 7.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH13977.1 - 2.2e-05 24.6 19.4 2.4 9.0 0.0 9.9 10 1 1 11 11 11 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEH13977.1 - 0.00044 20.5 4.4 1.1 9.6 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 CEH13977.1 - 0.1 12.5 3.2 58 3.8 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 CEH13978.1 - 1e-15 58.2 0.1 1.7e-15 57.4 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH13978.1 - 3.5e-15 56.0 0.6 1.6e-13 50.6 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CEH13978.1 - 3e-10 39.7 0.3 3.4e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.7 CEH13978.1 - 3.1e-08 32.4 1.4 9.1e-05 21.1 0.4 3.0 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 CEH13978.1 - 9.1e-06 25.2 0.3 1.5e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 CEH13978.1 - 1.9e-05 24.3 0.2 3.5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CEH13978.1 - 3.3e-05 23.1 0.5 0.00039 19.7 0.3 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1100 PF06500.6 CEH13978.1 - 0.0019 16.8 0.0 0.0032 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.6 CEH13978.1 - 0.02 14.6 0.0 0.093 12.4 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.8 CEH13978.1 - 0.19 9.9 0.1 1.7 6.8 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF619 PF04768.8 CEH13980.1 - 9.1e-45 152.1 0.0 1.8e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 CEH13980.1 - 1.1e-26 93.4 0.0 2.5e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 CEH13980.1 - 1.5e-21 77.0 0.0 4.3e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 CEH13980.1 - 5.4e-08 32.9 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 CEH13980.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pam16 PF03656.8 CEH13980.1 - 0.43 10.3 0.0 0.43 10.3 0.0 2.5 3 0 0 3 3 3 0 Pam16 CENP-F_leu_zip PF10473.4 CEH13981.1 - 0.0027 17.5 11.1 0.0038 17.0 1.1 2.3 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 CEH13981.1 - 0.0028 17.5 10.6 0.032 14.0 2.2 2.2 2 0 0 2 2 2 2 Tropomyosin like Spc7 PF08317.6 CEH13981.1 - 0.0097 14.5 3.6 0.44 9.1 0.3 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein IncA PF04156.9 CEH13981.1 - 0.047 13.2 10.5 0.078 12.5 2.2 2.4 2 0 0 2 2 2 0 IncA protein Lectin_N PF03954.9 CEH13981.1 - 0.09 12.1 0.3 0.21 10.9 0.2 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF1843 PF08898.5 CEH13981.1 - 0.094 12.7 0.1 0.094 12.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) FlxA PF14282.1 CEH13981.1 - 0.23 11.4 5.6 0.077 12.9 1.1 2.4 2 0 0 2 2 2 0 FlxA-like protein Filament PF00038.16 CEH13981.1 - 0.29 10.5 8.4 2.5 7.5 1.2 2.3 2 0 0 2 2 2 0 Intermediate filament protein Sec8_exocyst PF04048.9 CEH13981.1 - 0.9 9.1 3.1 7.9 6.1 0.2 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain HOOK PF05622.7 CEH13981.1 - 3 5.5 7.1 0.12 10.1 0.5 1.6 2 0 0 2 2 2 0 HOOK protein Cortex-I_coil PF09304.5 CEH13981.1 - 5.2 7.1 11.8 0.11 12.5 2.5 2.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil S1 PF00575.18 CEH13982.1 - 1.1e-35 121.5 4.7 1.7e-11 44.0 0.2 9.4 12 0 0 12 12 12 4 S1 RNA binding domain TPR_19 PF14559.1 CEH13982.1 - 3.1e-08 33.8 0.0 0.083 13.2 0.0 4.6 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CEH13982.1 - 4.2e-07 30.0 4.6 0.17 12.5 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEH13982.1 - 9.5e-07 28.6 0.1 0.03 14.2 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 CEH13982.1 - 2e-06 27.7 11.6 6.9e-06 25.9 0.0 4.0 2 1 3 5 5 5 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 CEH13982.1 - 2e-06 28.2 7.2 0.007 17.0 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEH13982.1 - 0.0025 18.1 0.0 0.0025 18.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEH13982.1 - 0.0043 16.8 0.5 6.8 6.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Nop14 PF04147.7 CEH13982.1 - 5.9 4.6 60.6 0.028 12.3 2.4 3.4 3 0 0 3 3 3 0 Nop14-like family RNase_PH PF01138.16 CEH13983.1 - 1.9e-12 47.6 0.0 3.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CEH13983.1 - 3.6e-05 23.6 0.0 6.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 LNS2 PF08235.8 CEH13984.1 - 6e-66 220.8 0.1 1.6e-52 177.2 0.0 2.3 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CEH13984.1 - 2.2e-26 91.6 0.0 1.8e-16 59.7 0.0 2.7 2 0 0 2 2 2 2 lipin, N-terminal conserved region Peptidase_M24 PF00557.19 CEH13985.1 - 1.7e-42 145.3 0.0 2.7e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CEH13985.1 - 7.1e-24 84.7 0.0 7.2e-21 75.0 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Yip1 PF04893.12 CEH13986.1 - 1.1e-08 34.8 11.0 1.9e-08 33.9 7.6 1.4 1 0 0 1 1 1 1 Yip1 domain MFS_1 PF07690.11 CEH13988.1 - 1.2e-13 50.4 50.0 2.8e-08 32.8 20.7 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.8 CEH13988.1 - 0.0016 16.6 6.2 0.0016 16.6 4.3 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector CRPA PF05745.6 CEH13988.1 - 0.047 13.4 0.4 5.4 6.8 0.2 3.3 2 1 1 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Condensation PF00668.15 CEH13989.1 - 6e-90 301.1 0.0 4e-39 134.2 0.0 3.3 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 CEH13989.1 - 1.2e-87 293.9 0.0 1.8e-87 293.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 CEH13989.1 - 5.4e-21 74.6 0.9 9.3e-07 29.0 0.1 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site AATase PF07247.7 CEH13989.1 - 0.0087 14.6 0.0 3.8 5.9 0.0 3.1 3 0 0 3 3 3 2 Alcohol acetyltransferase PS_Dcarbxylase PF02666.10 CEH13989.1 - 0.18 11.0 0.0 0.39 9.9 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase ECH PF00378.15 CEH13990.1 - 7e-53 179.2 0.0 1.1e-48 165.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family DUF566 PF04484.7 CEH13990.1 - 1.4 8.3 7.3 2.3 7.6 5.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Acetyltransf_8 PF13523.1 CEH13991.1 - 3.7e-24 85.3 0.4 8.6e-24 84.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.8 CEH13992.1 - 3.7e-18 65.8 0.7 1.6e-17 63.7 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 CEH13992.1 - 7.7e-09 35.1 0.0 1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CEH13992.1 - 2.5e-07 30.5 0.1 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CEH13992.1 - 3.8e-06 26.5 0.0 7.4e-06 25.5 0.0 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 CEH13992.1 - 4.1e-06 26.1 0.6 0.033 13.4 0.4 2.5 1 1 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 CEH13992.1 - 0.00037 19.3 0.0 0.00054 18.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 CEH13992.1 - 0.00078 19.3 0.8 0.011 15.6 0.4 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 CEH13992.1 - 0.003 16.1 0.0 0.0048 15.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) ABC_membrane PF00664.18 CEH13993.1 - 1.5e-66 224.6 17.4 2.1e-34 119.2 2.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEH13993.1 - 8.8e-48 162.0 0.0 4.3e-26 91.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 CEH13993.1 - 4e-08 32.8 0.9 0.0011 18.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.14 CEH13993.1 - 2e-07 30.4 0.2 0.067 12.4 0.0 3.7 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CEH13993.1 - 3.2e-07 31.1 0.1 0.0041 17.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CEH13993.1 - 5.5e-07 29.0 0.4 0.0058 16.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CEH13993.1 - 3.8e-06 27.0 1.3 0.031 14.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 CEH13993.1 - 1.1e-05 25.1 6.2 0.12 11.9 0.1 3.3 3 0 0 3 3 3 3 Conserved hypothetical ATP binding protein DUF258 PF03193.11 CEH13993.1 - 1.6e-05 24.1 0.5 0.036 13.2 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 CEH13993.1 - 2.5e-05 24.0 0.7 0.19 11.4 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CEH13993.1 - 2.6e-05 24.2 5.0 0.0066 16.4 0.1 3.3 4 0 0 4 4 2 2 AAA ATPase domain AAA_10 PF12846.2 CEH13993.1 - 2.8e-05 23.7 2.8 0.081 12.3 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_21 PF13304.1 CEH13993.1 - 8.4e-05 22.6 0.0 6.2 6.6 0.0 4.0 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.18 CEH13993.1 - 0.0001 22.2 0.4 0.19 11.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 CEH13993.1 - 0.00012 22.5 0.4 0.6 10.6 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 CEH13993.1 - 0.00013 22.3 0.1 0.22 11.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CEH13993.1 - 0.00015 21.3 0.6 0.0047 16.4 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 CEH13993.1 - 0.0002 21.2 4.6 0.0024 17.7 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 CEH13993.1 - 0.00024 20.2 3.5 0.28 10.2 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin UPF0079 PF02367.12 CEH13993.1 - 0.00028 20.4 1.0 1.8 8.2 0.0 3.4 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 CEH13993.1 - 0.00034 20.9 1.1 0.84 9.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.4 CEH13993.1 - 0.00041 19.0 1.8 0.057 12.0 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 CEH13993.1 - 0.00042 19.3 0.0 0.096 11.5 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 CEH13993.1 - 0.00072 19.3 0.0 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 CEH13993.1 - 0.00075 19.6 0.1 1.3 9.2 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_30 PF13604.1 CEH13993.1 - 0.001 18.6 3.5 0.26 10.8 0.1 3.1 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CEH13993.1 - 0.0034 16.8 0.2 0.74 9.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 CEH13993.1 - 0.0084 15.7 2.5 1.4 8.5 0.2 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 CEH13993.1 - 0.0086 16.2 1.2 1.7 8.8 0.1 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 CEH13993.1 - 0.011 15.2 2.6 1.2 8.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 CEH13993.1 - 0.012 15.4 1.7 0.97 9.2 0.3 2.4 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 CEH13993.1 - 0.021 14.7 4.6 1.9 8.3 0.2 3.3 3 0 0 3 3 2 0 AAA domain ArgK PF03308.11 CEH13993.1 - 0.026 13.2 2.5 0.13 10.9 0.1 2.6 3 0 0 3 3 3 0 ArgK protein NTPase_1 PF03266.10 CEH13993.1 - 0.05 13.3 0.7 2.5 7.8 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 CEH13993.1 - 0.069 13.0 0.1 18 5.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.17 CEH13993.1 - 0.12 11.8 4.2 0.93 8.8 0.1 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 CEH13993.1 - 0.12 11.8 1.0 8.5 5.8 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DEAD PF00270.24 CEH13993.1 - 0.14 11.6 1.4 8.3 5.8 0.0 3.6 4 0 0 4 4 4 0 DEAD/DEAH box helicase NB-ARC PF00931.17 CEH13993.1 - 0.17 10.7 1.0 4.7 5.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF3584 PF12128.3 CEH13993.1 - 0.17 9.2 0.2 0.26 8.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_5 PF07728.9 CEH13993.1 - 0.19 11.4 1.2 54 3.4 0.1 3.7 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 CEH13993.1 - 0.23 10.8 0.3 10 5.4 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 CEH13993.1 - 0.27 10.7 0.4 26 4.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_35 PF14516.1 CEH13993.1 - 0.39 9.3 0.1 2.1 6.8 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 CEH13993.1 - 0.67 9.8 6.6 2.4 8.1 0.1 3.3 3 0 0 3 3 3 0 AAA domain PRK PF00485.13 CEH13993.1 - 0.89 9.0 2.8 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_PrkA PF08298.6 CEH13993.1 - 3.5 6.2 2.9 4.3 5.9 0.1 2.4 3 0 0 3 3 3 0 PrkA AAA domain Coprogen_oxidas PF01218.13 CEH13998.1 - 8.1e-104 346.3 2.6 1.9e-67 226.9 0.4 3.9 2 2 0 2 2 2 2 Coproporphyrinogen III oxidase START PF01852.14 CEH13999.1 - 3.7e-06 26.4 0.1 5.3e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 START domain AIRC PF00731.15 CEH14000.1 - 1.1e-62 209.7 0.5 2.1e-62 208.8 0.4 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 CEH14000.1 - 1.1e-53 181.1 0.0 1.8e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CEH14000.1 - 5.9e-12 45.6 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CEH14000.1 - 0.00017 20.9 0.0 0.00033 19.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 3HCDH_N PF02737.13 CEH14000.1 - 0.0025 17.5 0.1 0.007 16.0 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.8 CEH14000.1 - 0.0031 16.9 0.0 0.017 14.5 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 CEH14000.1 - 0.016 13.9 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon CoA_binding_2 PF13380.1 CEH14000.1 - 0.085 13.0 0.3 24 5.1 0.1 3.3 2 1 1 3 3 3 0 CoA binding domain ATP-grasp_3 PF02655.9 CEH14000.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain SGL PF08450.7 CEH14001.1 - 2.7e-25 89.2 0.1 6.9e-25 87.8 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CEH14001.1 - 0.0012 18.8 0.0 0.0038 17.2 0.0 1.9 1 0 0 1 1 1 1 Strictosidine synthase NHL PF01436.16 CEH14001.1 - 0.0019 18.0 0.6 1.2 9.2 0.0 3.6 3 0 0 3 3 3 1 NHL repeat Arylesterase PF01731.15 CEH14001.1 - 0.017 15.0 0.0 0.044 13.7 0.0 1.8 1 1 0 1 1 1 0 Arylesterase Fasciclin PF02469.17 CEH14002.1 - 1e-13 51.4 0.0 1.7e-10 40.9 0.0 3.8 3 1 0 3 3 3 2 Fasciclin domain FH2 PF02181.18 CEH14003.1 - 2.4e-77 260.3 0.0 2.5e-76 257.0 0.0 2.3 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 CEH14003.1 - 3.9e-24 85.0 0.0 6.7e-19 67.9 0.0 2.7 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 CEH14003.1 - 1e-05 25.0 0.1 3.9e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain Gon7 PF08738.5 CEH14003.1 - 0.19 11.7 3.9 1.1 9.3 1.7 3.0 1 1 1 2 2 2 0 Gon7 family Glycos_transf_4 PF00953.16 CEH14003.1 - 0.26 11.0 0.0 0.53 10.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 4 Atg14 PF10186.4 CEH14003.1 - 0.76 8.6 18.6 0.22 10.4 3.1 2.7 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 RCC1 PF00415.13 CEH14004.1 - 6.6e-20 71.0 0.0 0.0021 18.2 0.0 6.7 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CEH14004.1 - 4.5e-08 32.4 3.0 0.028 14.0 0.1 5.1 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat SBP_bac_10 PF07596.6 CEH14004.1 - 0.0004 20.4 0.4 0.00065 19.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1559) IMPDH PF00478.20 CEH14005.1 - 2.5e-134 447.6 1.2 3e-134 447.3 0.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CEH14005.1 - 4.9e-18 64.6 0.1 8.2e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 CEH14005.1 - 2.1e-10 40.3 4.8 5.1e-08 32.4 2.6 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 CEH14005.1 - 4.7e-09 35.5 0.7 1.6e-08 33.7 0.6 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CEH14005.1 - 7.4e-09 35.1 0.2 2e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 CEH14005.1 - 0.00065 18.8 1.1 0.0016 17.5 0.8 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 CEH14005.1 - 0.014 14.3 0.3 0.3 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) EAL PF00563.15 CEH14005.1 - 0.021 14.2 0.1 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 EAL domain Dus PF01207.12 CEH14005.1 - 0.13 11.1 0.5 1 8.1 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 CEH14005.1 - 0.46 9.3 3.9 0.21 10.4 0.3 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase GTP_EFTU PF00009.22 CEH14007.1 - 5.7e-45 153.0 0.0 8.7e-45 152.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CEH14007.1 - 3.1e-22 78.5 0.9 1.2e-21 76.7 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CEH14007.1 - 1.2e-08 34.9 2.5 3.4e-08 33.4 1.7 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEH14007.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CEH14007.1 - 0.018 14.6 1.8 0.15 11.6 0.6 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 4 IstB_IS21 PF01695.12 CEH14007.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2631 PF10939.3 CEH14008.1 - 0.14 12.0 0.7 0.25 11.2 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2631) MRP-S33 PF08293.6 CEH14009.1 - 1.1e-12 47.8 0.0 1.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PGM_PMM_I PF02878.11 CEH14010.1 - 3.8e-17 62.0 0.1 4.7e-08 32.6 0.0 3.3 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 CEH14010.1 - 7.1e-12 45.1 0.0 2.3e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 CEH14010.1 - 1.9e-11 44.1 0.2 1.4e-10 41.4 0.0 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CEH14010.1 - 0.0047 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF3436 PF11918.3 CEH14010.1 - 0.08 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3436) ASD1 PF08688.5 CEH14011.1 - 0.025 14.3 0.7 0.033 13.9 0.5 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 ArfGap PF01412.13 CEH14013.1 - 4.4e-36 123.2 0.2 1.2e-35 121.7 0.2 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 CEH14013.1 - 2.9e-07 30.6 0.0 7.1e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 PH domain BAR PF03114.13 CEH14013.1 - 0.13 11.7 3.0 0.24 10.8 2.1 1.4 1 0 0 1 1 1 0 BAR domain Antigen_Bd37 PF11641.3 CEH14013.1 - 0.35 10.1 0.0 0.68 9.1 0.0 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Pyr_redox_2 PF07992.9 CEH14014.1 - 7.8e-24 84.6 0.0 9.1e-14 51.8 0.0 4.1 2 2 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEH14014.1 - 8.3e-12 45.3 0.0 1.6e-10 41.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEH14014.1 - 0.00017 21.7 0.0 0.038 14.0 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF1546 PF07571.8 CEH14015.1 - 0.057 13.5 0.0 0.061 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) DUF4112 PF13430.1 CEH14016.1 - 2.4e-29 101.3 0.1 3e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) TctA PF01970.11 CEH14016.1 - 0.0029 16.0 0.0 0.004 15.6 0.0 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctA family TFIIS_C PF01096.13 CEH14018.1 - 3.6e-13 48.9 0.7 3.6e-13 48.9 0.5 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CEH14018.1 - 1.1e-09 37.7 0.9 1.1e-09 37.7 0.6 3.2 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 CEH14018.1 - 0.0013 18.9 0.8 0.0013 18.9 0.6 2.2 2 1 0 2 2 2 1 Restriction alleviation protein Lar Elf1 PF05129.8 CEH14018.1 - 0.0034 17.0 1.4 0.36 10.5 0.1 2.3 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 CEH14018.1 - 0.0098 15.6 9.1 0.012 15.3 1.1 2.7 2 1 0 2 2 2 1 Transposase zinc-ribbon domain DUF2197 PF09963.4 CEH14018.1 - 0.02 14.8 5.8 0.056 13.3 0.7 2.5 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF3268 PF11672.3 CEH14018.1 - 0.025 14.6 3.8 0.84 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Zn_Tnp_IS1 PF03811.8 CEH14018.1 - 0.042 13.3 1.9 0.042 13.3 1.3 2.3 2 0 0 2 2 2 0 InsA N-terminal domain TF_Zn_Ribbon PF08271.7 CEH14018.1 - 0.14 11.4 4.3 0.23 10.8 1.0 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding zf-IS66 PF13005.2 CEH14018.1 - 0.19 11.7 4.1 32 4.6 0.1 3.3 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-LYAR PF08790.6 CEH14018.1 - 0.22 11.2 1.8 2.9 7.6 0.1 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger C1_3 PF07649.7 CEH14018.1 - 0.22 11.5 0.7 0.22 11.5 0.5 3.2 4 0 0 4 4 4 0 C1-like domain DZR PF12773.2 CEH14018.1 - 0.25 11.1 7.7 2.4 8.0 0.1 3.0 2 1 1 3 3 3 0 Double zinc ribbon zf-CSL PF05207.8 CEH14018.1 - 0.31 10.5 8.6 4.6 6.8 0.5 3.2 2 2 0 2 2 2 0 CSL zinc finger HypA PF01155.14 CEH14018.1 - 0.36 10.5 5.2 0.13 11.9 0.8 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family C1_4 PF07975.7 CEH14018.1 - 0.41 10.6 10.1 0.51 10.3 0.3 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.1 CEH14018.1 - 0.47 10.7 4.7 14 6.0 0.2 2.8 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF3795 PF12675.2 CEH14018.1 - 0.51 10.5 3.0 12 6.1 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) CpXC PF14353.1 CEH14018.1 - 0.54 10.2 4.2 30 4.5 0.2 2.8 2 1 1 3 3 3 0 CpXC protein Rubredoxin PF00301.15 CEH14018.1 - 0.63 9.9 6.4 23 4.9 0.0 3.4 3 0 0 3 3 3 0 Rubredoxin C1_1 PF00130.17 CEH14018.1 - 0.88 9.3 9.2 0.79 9.5 0.2 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 CEH14018.1 - 2.8 7.9 13.5 5.5 7.0 0.5 3.7 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2H2_4 PF13894.1 CEH14018.1 - 3 8.3 6.0 6.4 7.3 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger IBR PF01485.16 CEH14018.1 - 4.9 7.1 11.9 17 5.3 3.9 3.1 1 1 1 2 2 2 0 IBR domain zinc_ribbon_5 PF13719.1 CEH14018.1 - 7.4 6.2 8.8 14 5.4 0.4 3.2 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CEH14018.1 - 8.4 6.1 8.2 10 5.8 1.4 2.9 2 2 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 CEH14018.1 - 9.4 5.5 10.8 1.3 8.3 0.2 3.2 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2 PF00096.21 CEH14018.1 - 9.9 6.7 11.0 6.9 7.2 0.2 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type Pkinase PF00069.20 CEH14019.1 - 1.1e-55 188.6 0.0 7.6e-55 185.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH14019.1 - 4.4e-25 88.2 0.0 1.4e-24 86.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PH_3 PF14593.1 CEH14019.1 - 2.3e-10 40.2 0.0 0.0004 20.2 0.0 2.3 2 0 0 2 2 2 2 PH domain Kinase-like PF14531.1 CEH14019.1 - 4.5e-10 38.9 0.0 7.3e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEH14019.1 - 0.022 13.8 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tox-ART-HYD1 PF15633.1 CEH14019.1 - 0.039 14.7 0.1 2.6 8.8 0.0 2.5 2 0 0 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase CDC45 PF02724.9 CEH14019.1 - 1.6 6.7 7.2 8.5 4.2 3.5 2.3 2 0 0 2 2 2 0 CDC45-like protein Cmc1 PF08583.5 CEH14020.1 - 3.7e-16 58.6 1.2 4.1e-16 58.5 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 CEH14020.1 - 0.041 13.3 0.4 0.049 13.0 0.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Barwin PF00967.12 CEH14020.1 - 0.098 12.3 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Barwin family CHCH PF06747.8 CEH14020.1 - 0.13 12.1 1.3 0.37 10.7 0.1 1.9 2 0 0 2 2 2 0 CHCH domain COX17 PF05051.8 CEH14020.1 - 0.31 11.1 2.0 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GatB_N PF02934.10 CEH14022.1 - 1.1e-47 162.2 0.1 1.6e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CEH14022.1 - 4e-18 65.5 0.0 1.6e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 GatB domain PI-PLC-X PF00388.14 CEH14023.1 - 4e-57 191.7 0.0 7.4e-57 190.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CEH14023.1 - 1.8e-35 121.4 0.0 4.8e-35 120.0 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 CEH14023.1 - 2.3e-07 30.7 0.3 1.9e-06 27.8 0.0 2.6 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.1 CEH14023.1 - 0.0002 21.4 0.1 0.00074 19.6 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair C2 PF00168.25 CEH14023.1 - 0.00078 19.2 0.0 0.02 14.7 0.0 2.5 2 0 0 2 2 2 1 C2 domain EF-hand_1 PF00036.27 CEH14023.1 - 0.012 14.8 0.0 2.3 7.7 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.1 CEH14023.1 - 0.1 12.3 0.1 1 9.0 0.1 2.4 1 1 1 2 2 2 0 EF hand OB_NTP_bind PF07717.11 CEH14027.1 - 2.1e-11 43.6 0.0 4.9e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CEH14027.1 - 5.7e-11 42.1 0.0 6.2e-10 38.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 CEH14027.1 - 8.2e-09 35.4 0.0 2.4e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 CEH14027.1 - 0.00096 18.6 1.9 0.95 8.9 0.0 2.6 2 1 0 2 2 2 2 DEAD/DEAH box helicase KIAA1328 PF15369.1 CEH14027.1 - 0.0018 18.1 1.5 0.0036 17.1 0.4 1.9 2 0 0 2 2 2 1 Uncharacterised protein KIAA1328 AAA_22 PF13401.1 CEH14027.1 - 0.0035 17.4 0.0 0.42 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CEH14027.1 - 0.0075 16.1 0.3 0.48 10.2 0.1 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UFD1 PF03152.9 CEH14028.1 - 1.4e-62 209.9 0.0 1.8e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF1295 PF06966.7 CEH14029.1 - 9.6e-52 175.6 1.3 1.4e-51 175.0 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 CEH14029.1 - 6.7e-06 25.9 1.9 7.1e-06 25.8 0.0 2.0 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 CEH14029.1 - 0.00086 19.3 0.0 0.00086 19.3 0.0 2.5 3 1 1 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.9 CEH14029.1 - 0.0067 16.6 0.6 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Mito_carr PF00153.22 CEH14030.1 - 8.2e-14 51.0 0.2 4.3e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Acyl-CoA_dh_2 PF08028.6 CEH14031.1 - 2.6e-08 34.1 0.1 4.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 CEH14031.1 - 0.0021 18.2 0.1 0.0032 17.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SKG6 PF08693.5 CEH14033.1 - 0.0091 15.2 1.9 0.022 14.0 0.4 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain OB_NTP_bind PF07717.11 CEH14034.1 - 4.1e-28 97.4 0.0 8.9e-28 96.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CEH14034.1 - 5.7e-28 96.9 0.2 2.2e-27 95.0 0.1 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CEH14034.1 - 7.8e-13 48.0 0.0 3e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEH14034.1 - 8.9e-08 31.8 0.1 1.7e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase S1 PF00575.18 CEH14034.1 - 3.4e-06 27.0 0.0 8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.1 CEH14034.1 - 0.00039 20.5 0.0 0.00098 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CEH14034.1 - 0.0016 17.3 0.0 0.0041 16.0 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 CEH14034.1 - 0.0099 15.6 0.7 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 CEH14034.1 - 0.021 15.1 0.3 0.58 10.4 0.1 3.0 2 1 0 2 2 1 0 ABC transporter Flavi_DEAD PF07652.9 CEH14034.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.10 CEH14034.1 - 0.046 13.5 0.0 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CEH14034.1 - 0.099 11.8 0.1 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein UPF0079 PF02367.12 CEH14034.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 CEH14034.1 - 0.18 11.7 0.0 1.1 9.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain Lipase_3 PF01764.20 CEH14035.1 - 9.1e-10 38.3 0.0 2.4e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Thaumatin PF00314.12 CEH14038.1 - 1.8e-11 43.9 2.9 4.5e-09 36.0 0.9 2.0 1 1 1 2 2 2 2 Thaumatin family PHO4 PF01384.15 CEH14039.1 - 4.9e-115 383.6 15.7 6.1e-115 383.3 10.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family Asp_protease_2 PF13650.1 CEH14040.1 - 0.00038 20.9 0.2 1.2 9.6 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 CEH14040.1 - 0.0004 20.1 0.2 0.25 11.2 0.3 3.0 2 1 1 3 3 3 2 gag-polyprotein putative aspartyl protease Sas10 PF09368.5 CEH14041.1 - 0.037 14.1 0.4 0.046 13.8 0.3 1.1 1 0 0 1 1 1 0 Sas10 C-terminal domain Bromo_TP PF07524.8 CEH14041.1 - 0.091 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Bromodomain associated Tet_JBP PF12851.2 CEH14049.1 - 6.4e-07 28.8 0.1 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily ABM PF03992.11 CEH14052.1 - 0.0004 20.3 0.0 0.00059 19.8 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase RPN7 PF10602.4 CEH14052.1 - 0.06 12.7 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 26S proteasome subunit RPN7 ADH_zinc_N PF00107.21 CEH14053.1 - 1.3e-17 63.5 1.2 1.3e-17 63.5 0.9 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH14053.1 - 3.5e-14 53.8 0.3 3.5e-14 53.8 0.2 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH14053.1 - 1e-08 34.9 0.1 4.8e-08 32.7 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 CEH14053.1 - 0.0067 16.0 0.7 0.011 15.3 0.5 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Abhydrolase_6 PF12697.2 CEH14054.1 - 5.8e-07 29.6 2.1 2.5e-06 27.5 1.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family SAP18 PF06487.7 CEH14054.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Sin_N PF04801.8 CEH14055.1 - 3.6e-30 105.1 0.0 4.9e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region Ribosomal_L21p PF00829.16 CEH14056.1 - 1.6e-10 40.9 0.2 2.2e-05 24.4 0.5 2.2 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein Peptidase_C1_2 PF03051.10 CEH14057.1 - 2.1e-134 448.3 0.3 8.3e-134 446.3 0.2 1.7 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 CEH14057.1 - 2.5e-06 27.5 0.2 0.0063 16.4 0.1 2.9 2 1 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.8 CEH14057.1 - 0.014 13.9 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family BssS PF13991.1 CEH14057.1 - 0.089 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 BssS protein family DAO PF01266.19 CEH14058.1 - 1.5e-40 139.1 0.0 9.1e-40 136.6 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEH14058.1 - 2e-06 27.7 0.2 3.6e-05 23.7 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CEH14058.1 - 2.7e-06 26.4 0.0 0.019 13.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 CEH14058.1 - 7e-06 26.3 0.0 0.0016 18.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEH14058.1 - 7.4e-05 22.7 0.0 0.0061 16.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEH14058.1 - 0.00047 19.3 0.2 0.0081 15.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 CEH14058.1 - 0.0038 16.9 0.0 0.009 15.6 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CEH14058.1 - 0.015 14.7 0.1 0.092 12.1 0.0 2.3 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 CEH14058.1 - 0.043 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 CEH14058.1 - 0.077 11.8 0.0 0.56 8.9 0.0 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_2 PF03446.10 CEH14058.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amino_oxidase PF01593.19 CEH14058.1 - 0.11 11.5 1.0 0.61 9.0 0.0 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 CEH14058.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sen15 PF09631.5 CEH14059.1 - 2.7e-14 53.2 0.1 2.2e-13 50.3 0.1 2.1 1 1 0 1 1 1 1 Sen15 protein Myc_N PF01056.13 CEH14059.1 - 0.0087 15.2 1.6 0.013 14.7 1.1 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Nucleoplasmin PF03066.10 CEH14059.1 - 0.0091 15.5 3.1 0.012 15.1 2.1 1.2 1 0 0 1 1 1 1 Nucleoplasmin Sigma70_ner PF04546.8 CEH14059.1 - 0.012 15.2 3.7 0.018 14.6 2.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 CEH14059.1 - 0.042 14.1 6.3 0.081 13.1 4.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 CEH14059.1 - 0.079 13.2 6.7 0.14 12.4 4.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF688 PF05097.7 CEH14059.1 - 0.32 9.9 2.8 0.53 9.1 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF688) DUF3245 PF11595.3 CEH14059.1 - 0.41 10.8 5.2 0.72 10.1 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Bd3614_N PF14442.1 CEH14059.1 - 1.3 8.9 6.2 3.6 7.5 4.3 1.7 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Nop14 PF04147.7 CEH14059.1 - 2 6.2 5.8 2.6 5.8 4.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.1 CEH14059.1 - 3.2 7.9 7.2 6.4 6.9 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.7 CEH14059.1 - 6.6 5.9 6.7 9 5.4 4.6 1.1 1 0 0 1 1 1 0 NOA36 protein Baculo_PEP_C PF04513.7 CEH14060.1 - 0.3 10.8 7.1 9.8 6.0 0.7 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PAM2 PF07145.10 CEH14060.1 - 0.58 9.7 15.8 0.15 11.6 0.1 4.0 5 0 0 5 5 5 0 Ataxin-2 C-terminal region PUF PF00806.14 CEH14061.1 - 2.9e-64 209.0 10.6 3e-09 35.8 0.0 8.7 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 CEH14061.1 - 0.043 14.0 0.1 2.5 8.4 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function DUF260 AMP-binding PF00501.23 CEH14062.1 - 4.2e-76 255.9 0.0 5.8e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 CEH14062.1 - 6.8e-25 87.5 0.0 1.2e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 CEH14062.1 - 5.5e-07 29.7 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 CEH14062.1 - 3.2e-05 24.7 0.0 0.00011 23.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UQ_con PF00179.21 CEH14064.1 - 1.3e-47 160.7 0.0 1.6e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEH14064.1 - 6e-07 29.2 0.0 8.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B CWC25 PF12542.3 CEH14065.1 - 7.1e-21 74.4 0.1 7.1e-21 74.4 0.1 3.2 3 0 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.4 CEH14065.1 - 2.2e-13 49.9 9.5 2.2e-13 49.9 6.6 4.3 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Met_10 PF02475.11 CEH14066.1 - 7.3e-58 195.4 0.0 1.1e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein UEV PF05743.8 CEH14068.1 - 1e-34 118.8 0.1 1.7e-34 118.1 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 CEH14068.1 - 1.9e-24 85.0 0.2 3.8e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Vps23 core domain Arf PF00025.16 CEH14069.1 - 1e-56 190.9 0.0 1.2e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CEH14069.1 - 2.8e-10 39.7 0.0 3.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CEH14069.1 - 2.3e-08 34.5 0.0 3.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 CEH14069.1 - 3.9e-08 32.4 0.2 6.9e-05 21.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CEH14069.1 - 3.7e-07 30.1 0.0 5.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CEH14069.1 - 4.3e-07 29.4 0.0 5.4e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CEH14069.1 - 4.7e-07 29.1 0.0 5.6e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEH14069.1 - 0.0033 16.8 0.0 1.2 8.5 0.0 2.1 1 1 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CEH14069.1 - 0.021 14.1 0.0 0.036 13.3 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B ACT PF01842.20 CEH14069.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 ACT domain Rap_GAP PF02145.10 CEH14070.1 - 7e-53 178.8 0.0 1.2e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 CEH14070.1 - 1.8e-33 116.0 1.5 6.9e-30 104.3 0.8 3.4 4 0 0 4 4 4 2 Tuberin DUF3384 PF11864.3 CEH14070.1 - 1.7e-32 112.5 0.0 6.4e-27 94.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3384) Filament_head PF04732.9 CEH14071.1 - 9.2 7.0 8.5 2.5 8.8 4.1 1.4 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region DOT1 PF08123.8 CEH14073.1 - 9.2e-65 217.7 0.0 1.2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 CEH14073.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain BTB PF00651.26 CEH14074.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain GYF PF02213.11 CEH14075.1 - 0.001 18.6 0.1 0.0031 17.0 0.0 1.9 1 0 0 1 1 1 1 GYF domain CobN-Mg_chel PF02514.11 CEH14077.1 - 0.11 9.8 0.0 0.13 9.6 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase UQ_con PF00179.21 CEH14080.1 - 0.032 13.6 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Oxysterol_BP PF01237.13 CEH14081.1 - 1.3e-85 287.0 0.0 1.6e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF2215 PF10225.4 CEH14081.1 - 0.12 11.8 0.5 0.17 11.3 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) PBP1_TM PF14812.1 CEH14083.1 - 0.091 13.0 2.8 0.49 10.7 0.6 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2956 PF11169.3 CEH14083.1 - 0.14 12.1 0.2 18 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Macoilin PF09726.4 CEH14084.1 - 0.0022 16.3 19.4 0.0038 15.5 13.5 1.3 1 0 0 1 1 1 1 Transmembrane protein DUF3584 PF12128.3 CEH14084.1 - 0.6 7.3 26.3 0.82 6.9 18.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SPX PF03105.14 CEH14084.1 - 7.3 6.2 17.8 13 5.4 11.9 1.6 1 1 0 1 1 1 0 SPX domain Xpo1 PF08389.7 CEH14085.1 - 9.1e-22 77.5 0.0 1.3e-18 67.2 0.0 4.0 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.14 CEH14085.1 - 0.00065 19.5 0.4 0.0022 17.8 0.3 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF4131 PF13567.1 CEH14086.1 - 3.9 6.8 6.8 0.31 10.4 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF202 PF02656.10 CEH14086.1 - 9.5 6.5 9.6 19 5.5 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) F-box-like PF12937.2 CEH14087.1 - 1.4e-06 27.9 2.2 1.4e-06 27.9 1.5 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEH14087.1 - 2.5e-05 23.8 0.5 2.5e-05 23.8 0.3 2.1 2 0 0 2 2 2 1 F-box domain DUF2802 PF10975.3 CEH14087.1 - 0.05 13.3 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Tet_JBP PF12851.2 CEH14088.1 - 0.0064 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Phasin PF05597.6 CEH14088.1 - 0.021 14.5 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GCR1_C PF12550.3 CEH14089.1 - 0.087 12.6 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Peptidase_C50 PF03568.12 CEH14089.1 - 0.096 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C50 FliJ PF02050.11 CEH14089.1 - 0.68 10.0 8.2 2.2 8.3 1.6 2.7 2 0 0 2 2 2 0 Flagellar FliJ protein GGDN PF05165.7 CEH14090.1 - 0.062 12.3 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 GGDN family FAM74 PF15026.1 CEH14090.1 - 0.074 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 FAM74 protein MULE PF10551.4 CEH14091.1 - 1e-18 67.2 0.1 2.7e-18 65.9 0.0 1.8 1 1 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 CEH14091.1 - 9.2e-09 34.3 0.1 1.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family Abhydro_lipase PF04083.11 CEH14092.1 - 4.7e-14 51.4 0.0 8.1e-14 50.7 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CEH14092.1 - 1.4e-06 28.3 0.7 2.4e-06 27.5 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH14092.1 - 5e-06 26.3 0.0 8.8e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DoxX_2 PF13564.1 CEH14092.1 - 0.023 14.6 0.3 4.6 7.2 0.0 2.3 2 0 0 2 2 2 0 DoxX-like family His_biosynth PF00977.16 CEH14093.1 - 4.9e-37 127.4 1.5 6.2e-21 74.7 0.2 2.7 2 2 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.23 CEH14093.1 - 7.3e-25 87.5 0.0 1.3e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CEH14093.1 - 6.3e-08 32.3 0.1 2.1e-07 30.6 0.0 1.9 3 0 0 3 3 3 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 CEH14093.1 - 0.00017 21.2 0.0 0.0044 16.6 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 CEH14093.1 - 0.044 13.2 0.4 0.22 10.9 0.3 2.0 1 1 0 1 1 1 0 Peptidase C26 Ipi1_N PF12333.3 CEH14094.1 - 2.6e-11 43.3 6.6 6.2e-09 35.7 0.2 4.2 2 1 1 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation PhoD PF09423.5 CEH14095.1 - 1.2e-39 136.1 0.1 3.7e-37 127.9 0.0 3.0 2 1 0 2 2 2 2 PhoD-like phosphatase Glyco_hydro_43 PF04616.9 CEH14096.1 - 2.2e-06 26.9 0.1 2.3e-06 26.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Paf67 PF10255.4 CEH14098.1 - 3e-156 520.3 0.0 4.4e-156 519.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 CEH14098.1 - 0.0017 18.0 2.2 0.01 15.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CEH14098.1 - 0.0048 16.4 0.4 0.067 12.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CEH14098.1 - 1.8 8.7 9.1 1.3 9.2 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Med8 PF10232.4 CEH14098.1 - 6.8 6.1 5.9 14 5.0 1.8 2.7 3 0 0 3 3 3 0 Mediator of RNA polymerase II transcription complex subunit 8 Ras PF00071.17 CEH14099.1 - 1.3e-60 203.4 0.0 1.5e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH14099.1 - 6.6e-19 68.5 0.0 9.9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH14099.1 - 3.4e-13 49.2 0.0 4.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEH14099.1 - 2.4e-06 27.1 0.0 4.7e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEH14099.1 - 4e-06 26.1 0.0 4.9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CEH14099.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CEH14099.1 - 0.018 15.1 0.0 0.38 10.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEH14099.1 - 0.022 14.7 0.4 0.065 13.2 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CEH14099.1 - 0.029 13.5 0.1 0.11 11.6 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF258 G-alpha PF00503.15 CEH14099.1 - 0.053 12.2 0.4 4.4 5.8 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Big_3_2 PF12245.3 CEH14099.1 - 0.11 12.0 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) AAA_14 PF13173.1 CEH14099.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF1638 PF07796.6 CEH14099.1 - 0.19 11.3 0.5 1.2 8.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1638) tRNA-synt_2b PF00587.20 CEH14100.1 - 1.1e-21 77.2 0.0 1.6e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEH14100.1 - 2.1e-18 66.0 0.0 8.9e-08 31.9 0.0 4.1 3 1 2 5 5 5 2 Anticodon binding domain ProRS-C_1 PF09180.6 CEH14100.1 - 6.6e-12 45.1 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.10 CEH14100.1 - 4.6e-08 32.9 0.1 1.1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HMG_box PF00505.14 CEH14101.1 - 7.9e-13 48.4 20.4 3.8e-06 27.0 4.6 3.0 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CEH14101.1 - 5.3e-10 39.5 13.5 0.00011 22.4 1.2 2.9 2 0 0 2 2 2 2 HMG-box domain Arabino_trans_C PF14896.1 CEH14101.1 - 0.015 13.8 0.7 0.021 13.4 0.5 1.2 1 0 0 1 1 1 0 EmbC C-terminal domain DUF3856 PF12968.2 CEH14101.1 - 0.3 10.9 7.7 0.55 10.0 0.3 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) DUF3449 PF11931.3 CEH14101.1 - 3.3 7.1 17.5 0.39 10.2 0.9 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) RRS1 PF04939.7 CEH14102.1 - 1.2e-45 154.9 1.8 2e-45 154.2 1.2 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) UMP1 PF05348.6 CEH14103.1 - 3.2e-14 53.0 0.9 5.8e-14 52.1 0.6 1.6 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 Diphthamide_syn PF01866.12 CEH14104.1 - 1.8e-86 290.2 0.0 2.1e-30 106.0 0.0 4.1 3 1 1 4 4 4 4 Putative diphthamide synthesis protein BTB PF00651.26 CEH14105.1 - 8.1e-10 38.6 0.0 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain MFS_1 PF07690.11 CEH14106.1 - 1.4e-29 102.9 32.3 1.8e-29 102.5 22.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH14106.1 - 3.6e-15 55.4 0.5 5.1e-15 54.9 0.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 CEH14106.1 - 0.00051 18.3 5.2 0.00068 17.9 3.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.20 CEH14108.1 - 4.2e-65 219.4 0.0 7.2e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH14108.1 - 5.7e-36 123.9 0.0 2.9e-34 118.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH14108.1 - 4.5e-07 29.1 0.1 4.7e-06 25.7 0.1 2.3 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CEH14108.1 - 0.026 13.3 0.1 0.044 12.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 NT-C2 PF10358.4 CEH14110.1 - 1.2e-06 28.0 0.0 0.00025 20.5 0.0 2.2 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins NAD_binding_5 PF07994.7 CEH14111.1 - 4e-113 377.8 0.0 2.1e-112 375.4 0.0 1.8 1 1 1 2 2 2 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CEH14111.1 - 8.7e-42 141.4 0.1 1.7e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase COX6A PF02046.10 CEH14114.1 - 5.6e-30 103.6 0.0 6.7e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Cyclin PF08613.6 CEH14115.1 - 1.2e-13 51.6 0.0 2.4e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CEH14115.1 - 1.3e-05 24.7 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ABC_tran PF00005.22 CEH14116.1 - 8.5e-47 158.9 0.0 1.3e-27 96.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 CEH14116.1 - 1.1e-28 100.4 13.9 2.9e-13 49.8 0.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 CEH14116.1 - 1.5e-07 31.6 0.0 0.028 14.3 0.0 4.2 2 2 1 4 4 4 1 AAA domain SMC_N PF02463.14 CEH14116.1 - 3.1e-06 26.5 0.3 0.47 9.6 1.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CEH14116.1 - 7.7e-06 26.3 0.1 0.0039 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CEH14116.1 - 1.5e-05 24.4 0.3 0.033 13.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 CEH14116.1 - 1.6e-05 23.9 0.0 0.031 13.1 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 CEH14116.1 - 0.00016 22.1 0.1 1 9.8 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 CEH14116.1 - 0.0013 18.7 5.7 0.017 15.0 0.0 3.8 3 1 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.1 CEH14116.1 - 0.0026 17.6 3.5 1.5 8.7 0.0 3.3 3 0 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 CEH14116.1 - 0.0036 16.7 0.1 0.38 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CEH14116.1 - 0.0038 16.7 0.2 0.87 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain Dynamin_N PF00350.18 CEH14116.1 - 0.0079 16.0 2.1 0.073 12.8 0.1 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CEH14116.1 - 0.012 15.6 0.9 2.8 7.9 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CEH14116.1 - 0.023 14.2 0.0 6.7 6.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 CEH14116.1 - 0.025 15.4 2.4 5.6 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CEH14116.1 - 0.026 14.6 2.4 6.6 6.8 0.0 3.2 3 1 0 3 3 2 0 AAA domain MobB PF03205.9 CEH14116.1 - 0.033 13.8 1.6 6.9 6.3 0.1 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CEH14116.1 - 0.051 12.6 0.0 5.6 6.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 CEH14116.1 - 0.12 12.2 2.6 1.1 9.0 0.0 3.4 3 1 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 CEH14116.1 - 0.28 10.8 0.0 23 4.5 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase DUF87 PF01935.12 CEH14116.1 - 0.38 10.5 2.1 0.57 9.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 CEH14116.1 - 0.51 10.6 4.1 4.9 7.4 0.2 2.8 2 1 0 2 2 2 0 AAA domain Fructosamin_kin PF03881.9 CEH14117.1 - 1.8e-63 214.2 0.0 2.2e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 CEH14117.1 - 5.4e-05 23.0 0.0 9.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family TIM PF00121.13 CEH14118.1 - 1.5e-55 187.9 0.0 1.8e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase DUF829 PF05705.9 CEH14119.1 - 3.5e-24 85.8 0.1 1.5e-17 64.1 0.1 3.5 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) CheB_methylest PF01339.12 CEH14119.1 - 0.1 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 CheB methylesterase Zn_clus PF00172.13 CEH14123.1 - 0.82 9.6 3.7 1.8 8.5 2.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_22 PF13401.1 CEH14124.1 - 1e-15 58.0 0.0 2.9e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CEH14124.1 - 2e-08 34.4 0.0 4.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEH14124.1 - 1.1e-07 32.0 1.1 8.9e-06 25.8 0.5 3.5 2 1 1 3 3 3 1 AAA ATPase domain NACHT PF05729.7 CEH14124.1 - 0.00045 19.9 0.0 0.00095 18.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 CEH14124.1 - 0.00081 18.3 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 CEH14124.1 - 0.0018 18.1 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CEH14124.1 - 0.0055 16.4 0.0 0.048 13.3 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 CEH14124.1 - 0.069 12.1 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 CEH14124.1 - 0.081 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PIF1 PF05970.9 CEH14124.1 - 0.1 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.10 CEH14124.1 - 0.16 11.6 0.1 3.4 7.3 0.0 2.3 2 0 0 2 2 2 0 NTPase PSP1 PF04468.7 CEH14125.1 - 8.5e-28 96.1 1.5 8.6e-28 96.1 0.1 1.7 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Ded_cyto PF06920.8 CEH14126.1 - 1.9e-39 134.8 0.0 3.5e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 CEH14126.1 - 1.6e-30 106.0 0.0 6.9e-30 104.0 0.0 2.0 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Spc97_Spc98 PF04130.8 CEH14127.1 - 1.4e-32 112.7 0.0 1.9e-31 109.0 0.0 2.1 1 1 0 1 1 1 1 Spc97 / Spc98 family LRR_8 PF13855.1 CEH14128.1 - 0.0009 18.9 6.1 4 7.2 0.6 4.6 4 1 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 CEH14128.1 - 0.006 16.4 7.9 6.2 7.2 0.0 6.6 6 2 1 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.1 CEH14128.1 - 0.19 11.8 9.2 19 5.7 0.0 5.8 7 0 0 7 7 7 0 Leucine Rich repeat DUF4200 PF13863.1 CEH14129.1 - 0.0013 18.7 7.3 0.0013 18.7 5.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) Birna_RdRp PF04197.7 CEH14129.1 - 7.1 4.5 7.9 11 3.9 5.5 1.2 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) FAD_binding_3 PF01494.14 CEH14130.1 - 1.7e-08 33.8 0.5 1.5e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 CEH14130.1 - 8.6e-07 28.1 0.1 1.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEH14130.1 - 4.4e-06 26.6 0.1 1.6e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CEH14130.1 - 0.00038 19.5 0.6 0.077 11.9 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 CEH14130.1 - 0.0019 17.1 0.1 0.0033 16.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CEH14130.1 - 0.0026 17.6 0.0 0.0099 15.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CEH14130.1 - 0.0066 15.1 0.1 0.011 14.3 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase AlaDh_PNT_C PF01262.16 CEH14130.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 CEH14130.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CEH14130.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.5 CEH14130.1 - 0.032 13.0 0.0 0.052 12.3 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.9 CEH14130.1 - 0.077 11.4 0.1 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein G-patch PF01585.18 CEH14131.1 - 0.00019 21.1 2.8 0.00019 21.1 1.9 2.3 2 0 0 2 2 2 1 G-patch domain bZIP_1 PF00170.16 CEH14132.1 - 0.00011 22.0 7.1 0.00011 22.0 5.0 2.2 2 0 0 2 2 2 1 bZIP transcription factor Myb_DNA-binding PF00249.26 CEH14136.1 - 3.7e-30 103.7 4.3 8.4e-16 57.7 0.8 3.9 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH14136.1 - 2.1e-24 85.3 3.5 3.8e-16 58.9 0.1 4.4 2 1 2 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.3 CEH14136.1 - 0.0064 16.3 0.6 0.59 10.0 0.4 2.8 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 CEH14136.1 - 0.069 13.2 3.5 1.5 8.9 0.3 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain HUN PF08729.5 CEH14138.1 - 1.1e-08 34.7 0.1 2.5e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 CEH14138.1 - 2.6e-07 30.5 0.0 4.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Ubinuclein conserved middle domain WD40 PF00400.27 CEH14139.1 - 9.1e-38 126.8 6.2 5.6e-08 32.3 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CEH14139.1 - 7.2e-33 112.3 0.2 1.7e-32 111.0 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 CEH14139.1 - 0.00035 20.0 0.0 0.17 11.3 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 CEH14139.1 - 0.00038 20.2 0.3 0.0038 16.9 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PA_decarbox PF05870.6 CEH14140.1 - 4e-21 75.1 0.1 5.6e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Rad60-SLD_2 PF13881.1 CEH14141.1 - 5.9e-14 51.8 0.0 1.4e-13 50.6 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Erf4 PF10256.4 CEH14142.1 - 4e-28 97.6 0.0 4.9e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Ras PF00071.17 CEH14143.1 - 7.4e-64 214.0 0.1 8.9e-64 213.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH14143.1 - 3.6e-18 66.1 0.0 5.1e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH14143.1 - 4.5e-13 48.8 0.1 5.5e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEH14143.1 - 4.4e-05 22.7 0.0 5.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEH14143.1 - 7.5e-05 22.2 0.1 0.00019 20.9 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEH14143.1 - 0.00071 19.5 0.0 0.0015 18.4 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CEH14143.1 - 0.00087 18.5 0.0 0.0022 17.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CEH14143.1 - 0.012 14.8 0.0 0.59 9.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 CEH14143.1 - 0.027 14.4 0.1 0.084 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 CEH14143.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 CEH14143.1 - 0.04 13.1 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CEH14143.1 - 0.078 13.1 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CEH14143.1 - 0.08 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 CEH14143.1 - 0.091 13.0 0.2 0.51 10.6 0.1 2.0 1 1 0 1 1 1 0 ABC transporter DUF218 PF02698.12 CEH14145.1 - 0.013 14.9 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 DUF218 domain LSM PF01423.17 CEH14146.1 - 5.3e-09 35.4 0.1 6.5e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain ABC_tran PF00005.22 CEH14147.1 - 4.6e-43 146.8 0.0 6.2e-25 88.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CEH14147.1 - 2.4e-38 132.1 9.4 1.2e-19 70.8 2.2 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 CEH14147.1 - 1.8e-11 43.7 0.2 0.00013 21.2 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CEH14147.1 - 3.2e-10 40.4 0.0 0.06 13.3 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 CEH14147.1 - 8e-08 32.4 4.1 0.00027 20.9 1.8 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CEH14147.1 - 1.5e-07 30.7 0.1 0.0044 16.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 CEH14147.1 - 4.6e-07 29.0 0.0 0.0098 14.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 CEH14147.1 - 1.1e-06 28.1 0.0 0.021 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CEH14147.1 - 8.9e-06 25.4 0.2 0.059 13.0 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CEH14147.1 - 1.7e-05 24.4 0.0 0.084 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain MMR_HSR1 PF01926.18 CEH14147.1 - 3.5e-05 23.7 0.0 0.0079 16.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 CEH14147.1 - 4e-05 24.0 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CEH14147.1 - 9.4e-05 23.2 0.0 0.52 11.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 CEH14147.1 - 9.8e-05 21.8 2.1 0.049 13.0 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 CEH14147.1 - 0.00025 21.1 0.1 2.5 8.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 CEH14147.1 - 0.0013 19.2 0.2 0.67 10.4 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CEH14147.1 - 0.0014 18.1 0.0 0.18 11.2 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 CEH14147.1 - 0.0016 18.3 0.0 1.5 8.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CEH14147.1 - 0.0018 17.5 0.1 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 CEH14147.1 - 0.0019 18.5 0.8 1.2 9.3 0.1 2.8 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 CEH14147.1 - 0.002 16.8 0.0 1.4 7.4 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 CEH14147.1 - 0.0024 17.7 1.2 2.8 7.7 0.1 2.9 3 0 0 3 3 3 2 Dynamin family ATP_bind_1 PF03029.12 CEH14147.1 - 0.0038 16.8 0.1 1.7 8.1 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 CEH14147.1 - 0.0049 16.5 7.9 0.031 14.0 0.1 4.1 3 1 0 3 3 2 1 Part of AAA domain NTPase_1 PF03266.10 CEH14147.1 - 0.0054 16.4 0.3 0.47 10.1 0.0 2.4 2 0 0 2 2 2 1 NTPase DUF87 PF01935.12 CEH14147.1 - 0.0079 16.0 0.0 0.04 13.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 CEH14147.1 - 0.022 14.2 0.1 6.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 CEH14147.1 - 0.023 13.4 0.7 0.042 12.6 0.0 1.6 2 0 0 2 2 2 0 ArgK protein NACHT PF05729.7 CEH14147.1 - 0.027 14.1 0.8 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 CEH14147.1 - 0.028 14.1 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 CEH14147.1 - 0.037 14.2 0.3 4.1 7.6 0.0 3.5 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Pox_A32 PF04665.7 CEH14147.1 - 0.042 13.1 0.1 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.7 CEH14147.1 - 0.059 12.4 0.1 11 5.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.22 CEH14147.1 - 0.063 12.6 0.0 7.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CEH14147.1 - 0.4 10.1 1.1 9.8 5.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 CEH14147.1 - 0.6 9.8 3.2 15 5.3 0.0 3.6 5 0 0 5 5 3 0 AAA domain (dynein-related subfamily) RabGAP-TBC PF00566.13 CEH14149.1 - 9.5e-47 159.2 0.3 6.4e-41 140.1 0.1 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GET2 PF08690.5 CEH14149.1 - 0.076 12.2 0.8 0.29 10.3 0.1 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 DivIVA PF05103.8 CEH14149.1 - 1.5 8.9 10.5 0.21 11.6 2.3 2.5 2 0 0 2 2 2 0 DivIVA protein DUF685 PF05085.7 CEH14150.1 - 0.028 13.4 0.7 0.031 13.3 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF685) ArsA_ATPase PF02374.10 CEH14152.1 - 2.3e-110 368.3 4.0 1.5e-107 359.1 2.8 2.0 1 1 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CEH14152.1 - 8.6e-15 54.6 0.0 1.9e-14 53.5 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CEH14152.1 - 4.7e-07 29.8 0.0 5.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 CEH14152.1 - 1.8e-05 24.0 0.1 5.3e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CEH14152.1 - 0.00013 21.4 0.1 0.00059 19.3 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 CEH14152.1 - 0.0025 17.5 0.0 0.044 13.5 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 CEH14152.1 - 0.0032 16.7 0.0 0.0072 15.5 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein MipZ PF09140.6 CEH14152.1 - 0.0062 15.6 0.0 0.013 14.5 0.0 1.6 1 0 0 1 1 1 1 ATPase MipZ YhjQ PF06564.7 CEH14152.1 - 0.0068 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 CEH14152.1 - 0.011 15.1 0.7 0.12 11.7 0.2 2.5 2 1 1 3 3 3 0 AAA domain IstB_IS21 PF01695.12 CEH14152.1 - 0.052 12.9 0.2 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein VirC1 PF07015.6 CEH14152.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein SWIRM PF04433.12 CEH14153.1 - 2.9e-33 113.8 0.0 5.3e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 CEH14153.1 - 6.7e-07 29.3 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 CEH14153.1 - 0.00068 19.1 2.2 0.0015 17.9 1.5 1.6 1 1 0 1 1 1 1 Zinc finger, ZZ type Cellulase PF00150.13 CEH14154.1 - 8.2e-12 44.9 3.2 1.2e-11 44.3 2.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RhoGAP PF00620.22 CEH14155.1 - 1.6e-23 82.9 0.0 2.8e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 CEH14155.1 - 2.5e-14 53.1 0.0 7.1e-13 48.4 0.0 2.4 1 1 0 1 1 1 1 MyTH4 domain WW PF00397.21 CEH14155.1 - 2.4e-09 36.8 3.9 0.00015 21.5 2.7 2.5 2 0 0 2 2 2 2 WW domain MT-A70 PF05063.9 CEH14156.1 - 7.4e-34 116.8 0.0 1.8e-32 112.3 0.0 2.1 1 1 0 1 1 1 1 MT-A70 Septin PF00735.13 CEH14157.1 - 8.7e-108 359.5 0.0 8.7e-108 359.5 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CEH14157.1 - 1.3e-06 28.3 0.0 3.1e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CEH14157.1 - 7.3e-05 22.6 4.7 0.0088 15.8 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AAA_17 PF13207.1 CEH14157.1 - 0.00011 23.0 1.5 0.0019 19.0 1.0 2.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CEH14157.1 - 0.00064 18.9 0.4 0.0027 16.9 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 CEH14157.1 - 0.001 18.6 0.4 0.0025 17.3 0.1 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 CEH14157.1 - 0.0016 17.8 0.1 0.039 13.3 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CEH14157.1 - 0.0026 17.8 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CEH14157.1 - 0.0027 17.6 1.2 0.08 12.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AIG1 PF04548.11 CEH14157.1 - 0.0028 16.8 0.0 0.0056 15.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 CEH14157.1 - 0.0035 17.8 0.0 0.0091 16.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_33 PF13671.1 CEH14157.1 - 0.0035 17.2 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CEH14157.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 CEH14157.1 - 0.015 14.1 0.1 0.038 12.7 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 CEH14157.1 - 0.033 14.4 0.1 0.12 12.6 0.0 2.0 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 CEH14157.1 - 0.044 13.7 0.2 0.044 13.7 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 CEH14157.1 - 0.062 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 CEH14157.1 - 0.069 12.5 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain Gtr1_RagA PF04670.7 CEH14157.1 - 0.074 12.1 0.0 6 5.9 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 CEH14157.1 - 0.092 12.3 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CEH14157.1 - 0.096 12.1 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 CEH14157.1 - 0.11 12.3 0.1 0.81 9.4 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 CEH14157.1 - 0.12 12.6 3.8 0.31 11.3 0.2 2.9 2 1 1 3 3 3 0 AAA domain PduV-EutP PF10662.4 CEH14157.1 - 0.16 11.4 0.3 0.85 9.1 0.0 2.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 CEH14157.1 - 0.16 11.3 0.4 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Ras family ATP_bind_1 PF03029.12 CEH14157.1 - 0.23 10.9 2.0 1.2 8.6 0.2 2.7 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 CEH14157.1 - 1.6 8.5 6.4 0.88 9.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Pkinase PF00069.20 CEH14158.1 - 3e-53 180.6 0.0 1.1e-52 178.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH14158.1 - 1.1e-26 93.5 0.0 5.6e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEH14158.1 - 0.00048 19.1 0.1 0.017 14.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CEH14158.1 - 0.0019 17.9 0.2 0.26 10.9 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CEH14158.1 - 0.094 11.7 0.1 0.3 10.0 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 CEH14159.1 - 4.7e-06 26.2 5.5 0.62 10.0 0.0 4.9 4 1 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.1 CEH14159.1 - 0.013 15.8 1.0 9.6 6.6 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain TLP-20 PF06088.6 CEH14159.1 - 2.3 7.8 6.2 4.3 6.9 1.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SUR7 PF06687.7 CEH14160.1 - 1.3e-16 60.8 6.8 1.7e-16 60.4 4.7 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CEH14160.1 - 0.0069 16.0 6.4 0.0069 16.0 4.5 2.3 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.4 CEH14160.1 - 0.034 12.7 0.6 0.052 12.1 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2628 PF10947.3 CEH14160.1 - 1.7 8.5 5.1 0.22 11.3 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF4013 PF13197.1 CEH14160.1 - 2.7 7.2 16.9 0.33 10.2 7.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) adh_short PF00106.20 CEH14161.1 - 7.6e-05 22.6 0.2 0.068 13.0 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase AAA PF00004.24 CEH14162.1 - 3.3e-24 85.5 0.0 1e-23 84.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CEH14162.1 - 2.4e-05 23.9 0.1 6.3e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CEH14162.1 - 2.8e-05 24.2 2.2 0.00016 21.7 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain BCS1_N PF08740.6 CEH14162.1 - 4.6e-05 23.1 0.2 0.14 11.7 0.0 2.2 2 0 0 2 2 2 2 BCS1 N terminal AAA_5 PF07728.9 CEH14162.1 - 6.3e-05 22.7 0.0 0.00015 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CEH14162.1 - 6.5e-05 23.7 0.0 0.0002 22.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEH14162.1 - 6.6e-05 23.0 0.2 0.00046 20.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CEH14162.1 - 0.00048 18.9 0.1 0.0058 15.3 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 CEH14162.1 - 0.00076 18.9 0.0 0.0019 17.6 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 CEH14162.1 - 0.00094 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CEH14162.1 - 0.0017 17.7 0.4 0.0053 16.1 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 CEH14162.1 - 0.0019 18.5 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEH14162.1 - 0.0051 15.9 0.0 0.0099 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 CEH14162.1 - 0.0077 15.9 0.4 1.7 8.2 0.1 2.5 1 1 1 2 2 2 1 NACHT domain Sigma54_activ_2 PF14532.1 CEH14162.1 - 0.0088 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 CEH14162.1 - 0.01 15.9 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 CEH14162.1 - 0.011 15.7 0.4 0.11 12.3 0.2 2.6 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CEH14162.1 - 0.011 15.3 0.4 0.02 14.4 0.3 1.3 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CEH14162.1 - 0.013 14.6 0.0 0.041 12.9 0.0 1.8 2 0 0 2 2 1 0 KaiC AAA_11 PF13086.1 CEH14162.1 - 0.017 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CEH14162.1 - 0.028 14.2 0.0 0.072 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CEH14162.1 - 0.045 12.8 0.1 0.084 12.0 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 CEH14162.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF1033 PF06279.6 CEH14162.1 - 0.079 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) DUF815 PF05673.8 CEH14162.1 - 0.096 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KTI12 PF08433.5 CEH14162.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 CEH14162.1 - 0.13 11.8 0.8 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 CEH14162.1 - 0.13 11.1 0.2 0.8 8.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CEH14162.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter TIP120 PF08623.5 CEH14163.1 - 5.8e-50 169.1 1.7 2e-47 160.9 0.0 4.4 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) zf-DNL PF05180.7 CEH14163.1 - 2.6e-25 87.8 0.1 6.1e-25 86.7 0.1 1.7 1 0 0 1 1 1 1 DNL zinc finger HEAT_2 PF13646.1 CEH14163.1 - 4.5e-16 58.9 42.1 0.0001 22.5 0.1 10.1 6 4 3 9 9 9 6 HEAT repeats HEAT PF02985.17 CEH14163.1 - 1.5e-12 46.4 25.3 0.037 14.0 0.0 12.0 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 CEH14163.1 - 2.9e-10 40.3 38.5 0.1 13.0 0.1 11.8 9 2 4 13 13 13 6 HEAT-like repeat Adaptin_N PF01602.15 CEH14163.1 - 3.3e-08 32.2 12.1 0.085 11.1 0.1 5.5 4 1 2 6 6 6 3 Adaptin N terminal region Cnd1 PF12717.2 CEH14163.1 - 1.9e-07 31.1 0.6 0.037 13.8 0.0 4.5 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 CEH14163.1 - 8.1e-05 22.5 0.2 0.68 9.9 0.0 4.1 4 0 0 4 4 4 2 UME (NUC010) domain Arm PF00514.18 CEH14163.1 - 0.002 17.8 5.0 2.8 7.9 0.1 5.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF3731 PF12531.3 CEH14163.1 - 5.2 6.5 9.2 4.3 6.7 0.0 4.6 5 1 1 6 6 6 0 DNA-K related protein DUF3336 PF11815.3 CEH14164.1 - 9.3e-41 138.7 1.4 1.4e-40 138.1 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CEH14164.1 - 3.6e-20 72.7 0.0 7.9e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Nuclease_act PF08133.6 CEH14164.1 - 0.11 12.0 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Anticodon nuclease activator family Ferritin_2 PF13668.1 CEH14165.1 - 2.6e-38 131.0 3.6 4.7e-38 130.2 2.5 1.4 1 0 0 1 1 1 1 Ferritin-like domain Vps8 PF12816.2 CEH14166.1 - 1.4e-60 203.9 0.0 2.6e-60 203.0 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 CEH14166.1 - 0.021 14.3 0.3 5.8 6.5 0.0 3.2 3 0 0 3 3 3 0 Region in Clathrin and VPS WD40 PF00400.27 CEH14166.1 - 0.042 13.7 0.3 6.4 6.8 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat POTRA_2 PF08479.6 CEH14166.1 - 0.064 12.9 0.0 0.23 11.1 0.0 1.9 1 0 0 1 1 1 0 POTRA domain, ShlB-type TB2_DP1_HVA22 PF03134.14 CEH14167.1 - 7.4e-32 108.9 3.5 1e-31 108.4 2.4 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family zf-HC5HC2H_2 PF13832.1 CEH14168.1 - 1.4e-17 63.6 1.9 1.4e-17 63.6 1.3 4.1 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CEH14168.1 - 1.1e-14 54.3 3.2 1.1e-14 54.3 2.2 4.3 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.24 CEH14168.1 - 4.3e-12 45.5 25.3 1.5e-09 37.3 4.3 5.4 6 0 0 6 6 6 3 PHD-finger BAH PF01426.13 CEH14168.1 - 1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.1 CEH14168.1 - 1.2e-05 24.5 4.1 1.2e-05 24.5 2.8 5.2 7 0 0 7 7 7 2 PHD-finger GATA PF00320.22 CEH14168.1 - 0.0002 20.6 6.1 0.0002 20.6 4.3 3.4 3 0 0 3 3 3 1 GATA zinc finger Oxysterol_BP PF01237.13 CEH14170.1 - 7.4e-92 307.5 0.0 9.6e-92 307.1 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Oxysterol_BP PF01237.13 CEH14171.1 - 1.4e-114 382.2 0.0 2.1e-114 381.7 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 CEH14171.1 - 1.4e-16 60.2 2.1 5.2e-16 58.4 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 CEH14171.1 - 0.0018 18.5 0.7 0.0078 16.4 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 CEH14171.1 - 0.0039 17.3 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 PH domain MFS_1 PF07690.11 CEH14172.1 - 1.6e-26 92.8 42.7 7.4e-23 80.8 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH14172.1 - 6.5e-20 71.1 16.6 8.9e-14 50.9 4.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEH14173.1 - 1.6e-48 165.2 30.0 5.2e-43 147.1 13.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH14173.1 - 1.5e-14 53.4 7.5 1.5e-14 53.4 5.2 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 CEH14173.1 - 6e-09 34.6 0.6 1e-08 33.8 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 CEH14173.1 - 0.095 11.1 14.5 0.0095 14.4 5.4 2.5 2 2 0 2 2 2 0 Vacuole effluxer Atg22 like zf-UBR PF02207.15 CEH14174.1 - 1.9e-18 65.9 13.2 1.9e-18 65.9 9.1 2.9 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CEH14174.1 - 8.9e-13 47.7 0.2 4.3e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS EPTP PF03736.12 CEH14174.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 EPTP domain zf-met2 PF12907.2 CEH14175.1 - 2.7e-13 49.6 1.4 3.6e-13 49.2 1.0 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 CEH14175.1 - 5.6e-10 39.7 8.1 5.6e-10 39.7 5.6 1.5 2 0 0 2 2 2 1 4F5 protein family DUF1431 PF07248.7 CEH14175.1 - 0.033 14.1 0.4 0.037 14.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1431) zinc_ribbon_5 PF13719.1 CEH14175.1 - 0.088 12.4 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain HLH PF00010.21 CEH14176.1 - 1.9e-05 24.2 0.0 3.6e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Lactamase_B_2 PF12706.2 CEH14177.1 - 6.2e-29 100.9 0.5 3.7e-28 98.3 0.1 2.3 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CEH14177.1 - 3.2e-07 30.1 0.0 2.4e-06 27.3 0.0 2.4 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CEH14177.1 - 0.00087 18.9 0.2 0.0078 15.8 0.2 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily TPT PF03151.11 CEH14178.1 - 4.9e-33 113.9 6.8 4.9e-33 113.9 4.7 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CEH14178.1 - 8.8e-11 41.9 24.2 1.4e-05 25.1 5.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CEH14178.1 - 0.00037 19.5 18.2 0.00092 18.2 12.6 1.7 1 1 0 1 1 1 1 UAA transporter family Pox_A11 PF05061.8 CEH14178.1 - 0.23 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein DUF89 PF01937.14 CEH14179.1 - 1.3e-100 336.6 0.0 1.6e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF866 PF05907.8 CEH14180.1 - 3.2e-37 127.5 0.0 3.7e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Aldo_ket_red PF00248.16 CEH14181.1 - 1.8e-55 187.7 0.0 2.1e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAR2 PF05282.6 CEH14182.1 - 1.7e-28 99.6 0.0 2.5e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 AAR2 protein K-box PF01486.12 CEH14182.1 - 0.047 13.4 0.0 0.25 11.1 0.0 2.2 1 1 0 1 1 1 0 K-box region zf-met PF12874.2 CEH14183.1 - 3e-06 27.2 0.8 3e-06 27.2 0.6 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type FAM72 PF14976.1 CEH14184.1 - 3.3e-16 59.4 1.1 7.2e-16 58.3 0.8 1.5 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.9 CEH14184.1 - 0.0028 17.6 7.1 0.46 10.5 1.7 2.7 2 1 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MRC1 PF09444.5 CEH14184.1 - 0.0064 16.8 3.4 0.0064 16.8 2.3 2.4 3 0 0 3 3 3 1 MRC1-like domain Cullin PF00888.17 CEH14187.1 - 5.9e-135 451.0 0.0 7.7e-135 450.7 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CEH14187.1 - 4e-24 84.2 1.0 1e-23 82.9 0.7 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain AAA_10 PF12846.2 CEH14187.1 - 0.0052 16.2 2.5 1.9 7.8 0.2 3.6 3 1 0 3 3 3 2 AAA-like domain YbaJ PF10757.4 CEH14187.1 - 0.06 13.4 0.1 0.16 12.0 0.1 1.8 1 1 0 1 1 1 0 Biofilm formation regulator YbaJ UPF0220 PF05255.6 CEH14188.1 - 3e-51 172.9 0.2 3.7e-51 172.6 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Ank_2 PF12796.2 CEH14189.1 - 2.2e-18 66.3 0.0 2.9e-16 59.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CEH14189.1 - 3e-13 48.8 0.3 1.8e-05 24.2 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CEH14189.1 - 1.7e-11 43.9 0.0 3.2e-09 36.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEH14189.1 - 2.1e-11 43.9 0.0 6.6e-05 23.3 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH14189.1 - 7.8e-11 41.1 0.0 0.00092 19.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat DUF1320 PF07030.7 CEH14190.1 - 0.04 13.6 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) VHS PF00790.14 CEH14191.1 - 2.1e-27 95.4 0.5 4.2e-27 94.4 0.3 1.5 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 CEH14191.1 - 5.4e-17 61.1 0.1 1.2e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEH14191.1 - 7.7e-16 57.2 0.0 1.6e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEH14191.1 - 5.5e-12 44.9 0.0 1.2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 CEH14191.1 - 0.0013 18.6 2.6 0.0054 16.6 0.4 2.7 1 1 1 2 2 2 1 GAT domain PDCD2_C PF04194.8 CEH14192.1 - 2.2e-22 79.3 8.7 6.1e-17 61.7 0.0 3.1 4 0 0 4 4 4 2 Programmed cell death protein 2, C-terminal putative domain RR_TM4-6 PF06459.7 CEH14192.1 - 1.3 8.8 4.6 3 7.6 3.2 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pterin_bind PF00809.17 CEH14193.1 - 6.3e-66 221.7 0.7 6.3e-66 221.7 0.5 2.4 2 1 0 2 2 2 1 Pterin binding enzyme FolB PF02152.13 CEH14193.1 - 1.6e-41 140.9 0.3 9.3e-22 77.3 0.2 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.15 CEH14193.1 - 5.8e-36 123.0 0.0 1.1e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) EF-hand_1 PF00036.27 CEH14194.1 - 4.9e-42 138.0 12.4 3.8e-10 38.3 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CEH14194.1 - 4e-37 126.1 3.2 3.7e-20 71.8 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CEH14194.1 - 5.6e-33 112.3 10.7 6.6e-16 57.6 0.2 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CEH14194.1 - 1.9e-31 105.0 6.3 1.2e-09 37.2 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CEH14194.1 - 5.5e-28 95.0 6.5 3.2e-07 29.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CEH14194.1 - 8.7e-15 54.3 0.1 1.8e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CEH14194.1 - 2e-09 37.1 1.0 4.8e-05 23.0 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CEH14194.1 - 3.5e-09 36.6 0.0 0.00041 20.3 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CEH14194.1 - 6.1e-08 32.1 0.1 0.014 15.0 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CEH14194.1 - 3.4e-06 26.9 0.5 2.1e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 CEH14194.1 - 0.00035 20.0 2.0 0.0004 19.8 1.4 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EF-hand_like PF09279.6 CEH14194.1 - 0.00084 19.3 0.8 0.0055 16.6 0.1 2.3 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like Caleosin PF05042.8 CEH14194.1 - 0.0011 18.6 0.1 0.093 12.2 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein Poly_export PF02563.11 CEH14194.1 - 0.016 14.9 0.1 3.5 7.4 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein SapB_1 PF05184.10 CEH14194.1 - 0.018 14.8 0.1 33 4.4 0.0 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 TerB PF05099.8 CEH14194.1 - 0.02 14.6 0.2 0.6 9.8 0.0 2.0 1 1 1 2 2 2 0 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.11 CEH14194.1 - 0.024 14.6 1.3 2.3 8.2 0.1 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb4 MotA_activ PF09114.5 CEH14194.1 - 0.034 13.9 0.3 6.7 6.5 0.1 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 CEH14194.1 - 0.054 13.0 0.0 0.29 10.6 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 CEH14194.1 - 0.06 12.8 0.1 0.89 9.0 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 CEH14194.1 - 0.12 12.6 0.5 11 6.4 0.1 2.3 1 1 1 2 2 2 0 Toprim-like VCBS PF13517.1 CEH14194.1 - 2.1 8.7 5.8 16 5.9 0.2 2.5 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DEAD PF00270.24 CEH14195.1 - 1.9e-39 134.8 0.0 6.6e-39 133.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH14195.1 - 5.1e-27 93.5 0.0 1.8e-26 91.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CEH14195.1 - 0.009 15.1 0.0 0.009 15.1 0.0 3.7 2 1 2 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 CEH14195.1 - 0.013 13.9 0.0 0.24 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DAGAT PF03982.8 CEH14195.1 - 0.029 13.0 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase ResIII PF04851.10 CEH14195.1 - 0.068 13.0 2.9 0.088 12.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ROKNT PF08067.6 CEH14195.1 - 2.9 7.8 5.5 3.7 7.4 2.7 2.1 1 1 0 1 1 1 0 ROKNT (NUC014) domain Macoilin PF09726.4 CEH14195.1 - 3.4 5.8 16.9 4.9 5.3 11.7 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF427 PF04248.7 CEH14196.1 - 8e-22 76.7 2.5 3e-21 74.8 0.3 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF427) Ras PF00071.17 CEH14197.1 - 1.3e-29 102.6 0.0 7.2e-27 93.7 0.0 3.0 3 0 0 3 3 3 2 Ras family Miro PF08477.8 CEH14197.1 - 1e-09 38.8 0.0 2.4e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH14197.1 - 1e-05 24.8 0.0 2.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 CEH14197.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation L51_S25_CI-B8 PF05047.11 CEH14198.1 - 0.075 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain UQ_con PF00179.21 CEH14199.1 - 2.1e-27 95.2 0.0 2.5e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEH14199.1 - 4.3e-05 23.2 0.0 5.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CEH14199.1 - 0.0003 20.6 0.0 0.00041 20.2 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 CEH14199.1 - 0.0039 16.8 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.6 CEH14199.1 - 0.082 12.3 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 WD40 PF00400.27 CEH14200.1 - 7.7e-46 152.4 14.1 5.7e-08 32.3 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CEH14200.1 - 2.3e-07 29.3 0.9 0.0031 15.7 0.0 3.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CEH14200.1 - 9.5e-05 21.9 1.5 0.0099 15.3 1.0 3.0 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 CEH14200.1 - 0.028 13.1 0.0 0.39 9.4 0.0 2.5 1 1 0 1 1 1 0 Nup133 N terminal like PQQ_3 PF13570.1 CEH14200.1 - 0.05 13.9 1.4 0.22 11.8 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain zf-RING_5 PF14634.1 CEH14201.1 - 5.2e-06 26.0 4.8 9.9e-06 25.1 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CEH14201.1 - 7.4e-06 25.7 4.5 1.2e-05 25.0 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain FYVE PF01363.16 CEH14201.1 - 9.3e-05 22.2 4.9 0.00025 20.8 3.4 1.7 1 1 0 1 1 1 1 FYVE zinc finger zf-C3HC4_2 PF13923.1 CEH14201.1 - 0.00075 19.4 4.8 0.002 18.1 3.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEH14201.1 - 0.0027 17.4 1.8 0.0053 16.4 1.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CEH14201.1 - 0.0097 15.5 6.3 0.035 13.7 4.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 CEH14201.1 - 0.014 15.4 2.5 2 8.4 0.1 2.7 2 0 0 2 2 2 0 zinc-finger Rtf2 PF04641.7 CEH14201.1 - 0.016 14.4 0.2 0.016 14.4 0.1 2.2 1 1 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 CEH14201.1 - 0.026 14.3 7.9 0.7 9.8 5.9 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CEH14201.1 - 0.032 13.9 9.5 0.11 12.1 6.6 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-AD PF07776.10 CEH14201.1 - 0.075 13.0 0.3 0.99 9.4 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Zn-ribbon_8 PF09723.5 CEH14201.1 - 0.39 10.6 2.7 2.8 7.9 0.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-rbx1 PF12678.2 CEH14201.1 - 0.61 10.2 2.7 1.5 8.9 1.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DZR PF12773.2 CEH14201.1 - 3 7.7 7.4 36 4.2 0.2 2.4 1 1 1 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 CEH14201.1 - 5.1 6.9 6.8 11 5.9 0.9 2.5 1 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_5 PF13719.1 CEH14201.1 - 5.4 6.6 6.9 1.3 8.6 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CEH14201.1 - 9.9 5.9 6.8 2.7 7.7 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain CHAP PF05257.11 CEH14202.1 - 0.015 14.9 0.0 0.056 13.1 0.0 1.8 1 1 0 1 1 1 0 CHAP domain ING PF12998.2 CEH14203.1 - 6.9e-16 58.4 0.2 1.7e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CEH14203.1 - 3.1e-08 33.1 7.3 4.9e-08 32.5 5.0 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CEH14203.1 - 0.37 10.9 1.4 0.77 9.9 1.0 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PrmA PF06325.8 CEH14204.1 - 9.2e-13 47.9 0.0 1.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 CEH14204.1 - 1.2e-10 41.1 0.0 2.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH14204.1 - 4.9e-09 36.7 0.0 1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH14204.1 - 5.1e-09 36.1 0.2 6.6e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH14204.1 - 9.2e-07 28.7 0.0 2.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH14204.1 - 1.8e-06 28.2 0.0 8.1e-06 26.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH14204.1 - 2.1e-06 28.1 0.0 5.8e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEH14204.1 - 2.3e-06 27.0 0.1 4.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 CEH14204.1 - 9.9e-05 23.1 0.0 0.00052 20.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 CEH14204.1 - 0.00052 19.1 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.11 CEH14204.1 - 0.00058 18.8 0.0 0.00095 18.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.4 CEH14204.1 - 0.0014 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 CEH14204.1 - 0.0017 17.8 0.1 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 CEH14204.1 - 0.0038 16.6 0.1 0.0067 15.8 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.6 CEH14204.1 - 0.0051 15.5 0.0 0.008 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 CEH14204.1 - 0.0069 16.8 0.0 0.033 14.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 CEH14204.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 CEH14204.1 - 0.032 13.3 0.3 0.069 12.2 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 CEH14204.1 - 0.04 13.5 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CEH14204.1 - 0.047 12.6 0.0 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family C2 PF00168.25 CEH14205.1 - 1.3e-16 60.2 0.0 1.6e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain Hepatitis_core PF00906.15 CEH14205.1 - 0.62 9.7 3.6 1 9.0 2.5 1.3 1 0 0 1 1 1 0 Hepatitis core antigen PS_Dcarbxylase PF02666.10 CEH14206.1 - 5e-53 179.4 0.0 8.1e-53 178.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 CEH14206.1 - 2.3e-13 49.7 0.1 5.3e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 CEH14206.1 - 1.7 8.8 3.8 0.46 10.6 0.2 1.9 2 0 0 2 2 2 0 EF-hand domain pair TPR_1 PF00515.23 CEH14207.1 - 8e-53 174.0 30.4 1.4e-07 30.8 0.0 10.6 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 CEH14207.1 - 2e-50 168.3 36.5 1.1e-12 47.3 1.8 6.4 2 2 5 8 8 8 8 TPR repeat TPR_2 PF07719.12 CEH14207.1 - 4.4e-49 160.4 25.4 1.4e-05 24.6 0.0 10.3 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.1 CEH14207.1 - 5.9e-36 119.5 14.9 0.00046 19.7 1.9 10.1 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.1 CEH14207.1 - 5.4e-32 107.3 11.7 0.00049 20.4 0.0 9.4 4 3 6 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 CEH14207.1 - 2.2e-30 104.6 24.5 3.3e-07 30.8 0.0 7.9 4 2 3 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 CEH14207.1 - 2.4e-29 98.7 5.5 0.013 15.1 0.2 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 CEH14207.1 - 5e-26 90.4 20.4 5.4e-05 23.0 0.0 6.9 1 1 8 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 CEH14207.1 - 8.8e-26 87.9 20.8 0.0027 17.7 0.4 10.5 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 CEH14207.1 - 3.6e-24 84.8 16.5 3e-05 24.2 0.4 6.8 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 CEH14207.1 - 4.8e-21 73.7 17.5 0.0071 16.7 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 CEH14207.1 - 8.7e-15 54.3 9.8 0.004 16.9 0.0 6.3 1 1 8 9 9 9 7 Tetratricopeptide repeat Apc3 PF12895.2 CEH14207.1 - 2.9e-10 40.1 11.4 7.4e-05 22.8 1.3 3.9 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CEH14207.1 - 3e-07 29.7 10.1 0.0035 16.4 2.1 5.0 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 CEH14207.1 - 0.0018 18.1 12.9 8.5 6.4 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 CEH14207.1 - 0.002 18.1 3.0 0.11 12.6 0.1 4.5 4 2 2 6 6 5 1 Tetratricopeptide repeat TOM20_plant PF06552.7 CEH14207.1 - 0.024 14.2 1.2 7 6.1 0.0 3.8 2 2 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2225 PF09986.4 CEH14207.1 - 0.049 13.0 2.8 5.2 6.4 0.0 2.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.5 CEH14207.1 - 0.071 11.8 0.4 7.5 5.1 0.0 2.5 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 CEH14207.1 - 0.2 11.6 16.9 7 6.5 0.0 4.9 3 2 2 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 CEH14207.1 - 1.6 8.5 21.1 8.1 6.3 1.2 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat SNAP PF14938.1 CEH14207.1 - 1.8 7.6 18.5 8.5 5.4 0.5 4.9 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP DUF2580 PF10824.3 CEH14209.1 - 0.028 14.7 0.9 0.031 14.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) tRNA_m1G_MT PF01746.16 CEH14210.1 - 5.3e-25 88.0 0.0 5.9e-21 74.8 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase HSF_DNA-bind PF00447.12 CEH14211.1 - 4.5e-26 91.0 0.0 9.2e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding E1-E2_ATPase PF00122.15 CEH14212.1 - 1.4e-41 142.0 0.0 2.7e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CEH14212.1 - 4.1e-32 112.3 0.2 8.3e-32 111.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CEH14212.1 - 7.9e-15 54.7 12.8 0.00075 19.5 0.0 5.4 6 0 0 6 6 6 4 Heavy-metal-associated domain HAD PF12710.2 CEH14212.1 - 7.5e-13 49.0 0.0 1.7e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEH14212.1 - 0.00048 19.7 0.0 0.00094 18.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sulfate_transp PF00916.15 CEH14213.1 - 4.4e-44 150.5 0.7 4.4e-44 150.5 0.5 1.5 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 CEH14213.1 - 7.2e-14 51.3 0.0 1.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 CEH14213.1 - 4.4e-12 45.4 0.1 8.1e-12 44.6 0.1 1.4 1 0 0 1 1 1 1 STAS domain UCR_UQCRX_QCR9 PF05365.7 CEH14213.1 - 0.094 12.3 0.0 0.36 10.4 0.0 2.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Ras PF00071.17 CEH14214.1 - 1.5e-54 183.7 0.0 1.7e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH14214.1 - 1.6e-18 67.3 0.0 3.2e-18 66.3 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CEH14214.1 - 5.1e-12 45.3 0.0 6.4e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CEH14214.1 - 5.8e-07 29.4 0.0 8.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CEH14214.1 - 8.9e-07 28.2 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEH14214.1 - 1.9e-05 24.1 0.0 0.0002 20.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CEH14214.1 - 0.00038 19.6 0.0 0.00068 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CEH14214.1 - 0.00085 19.4 0.0 0.0016 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 CEH14214.1 - 0.0025 17.0 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 CEH14214.1 - 0.0031 17.2 0.0 0.021 14.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEH14214.1 - 0.004 17.1 0.0 0.0085 16.0 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 CEH14214.1 - 0.0051 16.5 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase ATP_bind_1 PF03029.12 CEH14214.1 - 0.0092 15.5 0.1 0.53 9.7 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CEH14214.1 - 0.011 15.2 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 CEH14214.1 - 0.012 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 CEH14214.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 CEH14214.1 - 0.016 14.2 0.1 0.29 10.1 0.0 2.2 2 0 0 2 2 2 0 Septin MobB PF03205.9 CEH14214.1 - 0.029 14.0 0.1 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CEH14214.1 - 0.032 13.6 0.0 0.077 12.4 0.0 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CEH14214.1 - 0.04 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 CEH14214.1 - 0.042 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 CEH14214.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 CEH14214.1 - 0.092 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Csm1 PF12539.3 CEH14215.1 - 1.1e-08 35.4 0.0 2.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Lzipper-MIP1 PF14389.1 CEH14215.1 - 0.076 13.1 0.4 0.076 13.1 0.3 3.0 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Spc7 PF08317.6 CEH14215.1 - 0.097 11.3 4.9 0.44 9.1 1.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.6 CEH14215.1 - 0.16 11.8 5.2 2.6 8.0 0.3 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.1 CEH14215.1 - 0.21 11.5 13.5 3.6 7.6 3.2 3.6 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Prefoldin_2 PF01920.15 CEH14215.1 - 0.76 9.5 11.9 0.46 10.2 0.8 3.6 2 1 1 3 3 3 0 Prefoldin subunit DUF342 PF03961.8 CEH14215.1 - 0.91 7.8 5.7 0.49 8.7 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Kinetocho_Slk19 PF12709.2 CEH14215.1 - 1.4 9.0 10.4 2.2 8.4 0.7 3.1 2 1 1 3 3 3 0 Central kinetochore-associated V_ATPase_I PF01496.14 CEH14215.1 - 4.1 5.1 13.4 2.1 6.0 1.2 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family HSCB_C PF07743.8 CEH14215.1 - 4.7 7.7 12.4 16 6.0 0.7 3.7 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Fib_alpha PF08702.5 CEH14215.1 - 5.6 7.0 11.2 0.15 12.1 0.9 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Actin PF00022.14 CEH14216.1 - 2.4e-54 184.2 0.0 4.1e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 Actin Chitin_synth_2 PF03142.10 CEH14217.1 - 2.3e-244 811.6 0.1 3.1e-244 811.2 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CEH14217.1 - 1.9e-13 50.5 7.4 1.9e-13 50.5 5.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEH14217.1 - 5.1e-13 49.3 0.1 2.3e-12 47.1 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CEH14217.1 - 1.3e-05 24.5 0.3 0.016 14.4 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Cyt-b5 PF00173.23 CEH14217.1 - 3.5e-05 23.5 0.0 0.00011 21.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 CEH14217.1 - 0.22 11.1 0.0 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 DSPc PF00782.15 CEH14219.1 - 4.7e-05 22.9 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CEH14219.1 - 0.0026 17.7 0.0 0.0075 16.3 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CEH14219.1 - 0.018 14.3 1.1 0.13 11.5 0.7 2.0 1 1 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.7 CEH14219.1 - 0.031 13.7 0.2 0.056 12.9 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Nodulin_late PF07127.6 CEH14222.1 - 0.035 14.2 0.2 0.056 13.5 0.1 1.3 1 0 0 1 1 1 0 Late nodulin protein RIP PF00161.14 CEH14223.1 - 0.0098 15.1 0.6 0.017 14.3 0.4 1.4 1 0 0 1 1 1 1 Ribosome inactivating protein DUF4192 PF13830.1 CEH14223.1 - 3.4 7.2 12.3 8.1 5.9 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Ferrochelatase PF00762.14 CEH14224.1 - 1.5e-103 346.1 0.0 1.7e-103 345.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 CEH14224.1 - 0.043 13.9 0.1 12 6.0 0.0 2.6 2 0 0 2 2 2 0 CbiX zf-RING_2 PF13639.1 CEH14225.1 - 2.1e-15 56.2 6.7 3.3e-15 55.6 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEH14225.1 - 9.4e-13 48.0 1.4 2.1e-12 46.9 1.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CEH14225.1 - 5.2e-10 39.1 5.6 9.2e-10 38.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH14225.1 - 5.6e-10 38.7 6.3 5.6e-10 38.7 4.4 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEH14225.1 - 1e-09 37.8 3.0 1.7e-09 37.1 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH14225.1 - 2.9e-08 33.3 3.9 4.4e-08 32.7 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CEH14225.1 - 3.3e-07 30.0 1.2 6e-07 29.2 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CEH14225.1 - 5.3e-05 22.8 2.0 9.2e-05 22.0 1.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger PHD PF00628.24 CEH14225.1 - 0.00027 20.5 5.2 0.00044 19.8 2.9 1.9 2 0 0 2 2 2 1 PHD-finger RINGv PF12906.2 CEH14225.1 - 0.00031 20.7 5.1 0.00058 19.8 3.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.1 CEH14225.1 - 0.00098 18.6 4.8 0.0021 17.6 3.2 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CEH14225.1 - 0.0023 17.4 1.9 0.0039 16.6 1.3 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 CEH14225.1 - 0.0038 17.1 5.8 0.014 15.3 4.0 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING-like PF08746.6 CEH14225.1 - 0.059 13.3 2.6 0.059 13.3 1.8 2.2 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_4 PF15227.1 CEH14225.1 - 0.085 12.7 4.9 0.22 11.4 3.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-HC5HC2H_2 PF13832.1 CEH14225.1 - 0.11 12.5 1.2 0.15 12.0 0.2 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 CEH14225.1 - 0.74 9.5 4.8 0.39 10.4 0.6 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-P11 PF03854.9 CEH14225.1 - 4 6.9 6.7 1.6 8.2 1.0 2.2 1 1 1 2 2 2 0 P-11 zinc finger SIN1 PF05422.7 CEH14227.1 - 2.6e-16 59.2 0.0 2.8e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) RA PF00788.18 CEH14227.1 - 9e-05 22.8 0.1 0.00022 21.6 0.0 1.7 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SIN1 PF05422.7 CEH14228.1 - 3e-16 59.0 0.0 6.1e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) Glyco_transf_15 PF01793.11 CEH14230.1 - 1.1e-134 448.5 6.8 1.4e-134 448.2 4.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF1917 PF08939.5 CEH14230.1 - 0.095 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) RPN7 PF10602.4 CEH14231.1 - 7.4e-46 155.7 0.7 1e-45 155.3 0.5 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CEH14231.1 - 2.6e-15 56.5 0.0 8.8e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 PCI domain SAC3_GANP PF03399.11 CEH14231.1 - 7.8e-05 22.3 0.2 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CEH14231.1 - 9.9e-05 22.1 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 ActA PF05058.7 CEH14232.1 - 0.11 10.4 0.8 0.13 10.2 0.6 1.1 1 0 0 1 1 1 0 ActA Protein Ribonuc_2-5A PF06479.7 CEH14233.1 - 1.1e-42 144.9 0.0 1.7e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 CEH14233.1 - 5.4e-37 127.3 0.0 4.6e-35 121.0 0.0 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH14233.1 - 8.9e-19 67.5 0.0 1.4e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CEH14233.1 - 0.019 14.0 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CEH14233.1 - 0.02 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CEH14233.1 - 0.031 14.0 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family BC10 PF06726.7 CEH14234.1 - 7.4e-11 41.9 9.0 1.8e-10 40.6 6.3 1.6 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Polysacc_deac_1 PF01522.16 CEH14235.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase UCR_hinge PF02320.11 CEH14238.1 - 0.00089 19.1 1.4 0.015 15.2 0.1 2.1 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 CEH14238.1 - 0.0049 16.7 2.6 0.029 14.2 0.7 2.5 2 1 1 3 3 3 2 CHCH domain COX17 PF05051.8 CEH14238.1 - 0.0086 16.0 2.4 1.1 9.3 0.3 2.5 1 1 0 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 CEH14238.1 - 0.014 15.1 3.6 0.25 11.1 0.5 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 CEH14238.1 - 0.1 12.4 3.2 3.9 7.3 0.1 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 CEH14238.1 - 0.28 11.2 6.2 4.3 7.4 0.9 2.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 CEH14238.1 - 0.84 9.6 3.3 3 7.9 2.3 1.8 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb FF PF01846.14 CEH14239.1 - 9.6e-25 86.2 15.1 2.2e-05 24.2 2.3 6.4 5 1 0 5 5 5 5 FF domain WW PF00397.21 CEH14239.1 - 2.9e-07 30.1 5.1 2.9e-07 30.1 3.5 2.6 2 0 0 2 2 2 1 WW domain DUF1510 PF07423.6 CEH14239.1 - 4.6 6.5 27.0 5.4 6.3 12.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) HECT PF00632.20 CEH14240.1 - 2.3e-95 319.4 0.0 2.9e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AAA PF00004.24 CEH14241.1 - 1e-32 113.0 0.2 2.5e-32 111.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEH14241.1 - 5.1e-09 36.3 0.0 1.5e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEH14241.1 - 1.4e-07 31.6 0.1 4.4e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CEH14241.1 - 2.3e-07 31.6 0.1 5.2e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEH14241.1 - 2.5e-07 30.6 0.0 7.1e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CEH14241.1 - 2e-06 27.3 0.2 0.0052 16.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.1 CEH14241.1 - 2.9e-06 27.5 0.0 5.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH14241.1 - 3.8e-06 26.5 0.2 2.3e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 CEH14241.1 - 1e-05 25.5 0.0 2.2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Arch_ATPase PF01637.13 CEH14241.1 - 1.3e-05 25.0 0.3 0.00083 19.1 0.2 2.2 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 CEH14241.1 - 2.5e-05 24.0 0.1 0.00035 20.2 0.1 2.3 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 CEH14241.1 - 3.7e-05 23.6 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CEH14241.1 - 0.00014 21.5 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CEH14241.1 - 0.00021 21.0 0.3 0.00081 19.1 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CEH14241.1 - 0.00034 20.2 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 CEH14241.1 - 0.00037 20.1 0.0 0.0009 18.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CEH14241.1 - 0.00047 20.1 0.0 0.00089 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEH14241.1 - 0.00054 19.0 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CEH14241.1 - 0.00061 19.9 0.0 0.0018 18.4 0.0 1.8 2 0 0 2 2 1 1 RNA helicase ABC_tran PF00005.22 CEH14241.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.13 CEH14241.1 - 0.0017 17.9 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 CEH14241.1 - 0.0017 17.7 0.0 0.0043 16.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Rad51 PF08423.6 CEH14241.1 - 0.0033 16.3 0.2 0.13 11.1 0.1 2.2 1 1 0 2 2 2 1 Rad51 Zeta_toxin PF06414.7 CEH14241.1 - 0.0041 16.2 0.0 0.0089 15.1 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin DUF2075 PF09848.4 CEH14241.1 - 0.0056 15.7 0.0 0.0074 15.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CEH14241.1 - 0.0056 16.2 0.1 0.015 14.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 CEH14241.1 - 0.0088 14.9 0.1 0.12 11.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 CEH14241.1 - 0.0091 15.1 0.0 0.025 13.7 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_13 PF13166.1 CEH14241.1 - 0.0092 14.4 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CEH14241.1 - 0.011 14.4 0.0 0.018 13.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MobB PF03205.9 CEH14241.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 CEH14241.1 - 0.012 14.6 0.0 1.5 7.7 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain TIP49 PF06068.8 CEH14241.1 - 0.013 14.2 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus NTPase_1 PF03266.10 CEH14241.1 - 0.013 15.1 0.5 0.059 13.0 0.0 2.1 1 1 1 2 2 2 0 NTPase PhoH PF02562.11 CEH14241.1 - 0.015 14.5 0.1 0.085 12.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 CEH14241.1 - 0.018 14.5 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family KTI12 PF08433.5 CEH14241.1 - 0.027 13.6 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.1 CEH14241.1 - 0.035 14.4 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CEH14241.1 - 0.042 12.6 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 CEH14241.1 - 0.043 12.9 0.0 0.24 10.4 0.0 1.9 1 1 1 2 2 2 0 KaiC T2SE PF00437.15 CEH14241.1 - 0.045 12.6 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_3 PF07726.6 CEH14241.1 - 0.048 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CEH14241.1 - 0.055 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 CEH14241.1 - 0.059 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CEH14241.1 - 0.068 12.6 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.17 CEH14241.1 - 0.07 12.5 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.21 CEH14241.1 - 0.071 12.5 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.14 CEH14241.1 - 0.13 11.6 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Abhydrolase_5 PF12695.2 CEH14242.1 - 8e-09 35.4 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CEH14242.1 - 4.1e-07 29.0 0.0 5.8e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CEH14242.1 - 8.2e-06 25.5 0.1 4.2e-05 23.2 0.1 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEH14242.1 - 0.00016 21.6 2.4 0.00038 20.4 1.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEH14242.1 - 0.00042 19.5 0.0 0.00079 18.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CEH14242.1 - 0.0028 17.1 0.0 0.009 15.4 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase F-box-like PF12937.2 CEH14243.1 - 1.9e-08 33.8 3.2 3.1e-08 33.2 2.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH14243.1 - 0.00047 19.7 1.3 0.0008 19.0 0.9 1.3 1 0 0 1 1 1 1 F-box domain RRP7 PF12923.2 CEH14243.1 - 0.34 10.9 3.9 0.73 9.8 2.7 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) UQ_con PF00179.21 CEH14244.1 - 1.3e-05 24.6 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DASH_Dad3 PF08656.5 CEH14245.1 - 2e-21 75.4 1.0 2.6e-21 75.1 0.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 PEX-1N PF09262.6 CEH14245.1 - 0.092 12.8 0.1 0.19 11.8 0.0 1.5 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal PAP_assoc PF03828.14 CEH14246.1 - 9.7e-16 57.4 0.0 2.7e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CEH14246.1 - 1.4e-06 28.5 0.0 2.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain FliE PF02049.13 CEH14246.1 - 0.065 13.2 1.3 0.2 11.6 0.1 2.4 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE Aminotran_4 PF01063.14 CEH14247.1 - 8.3e-23 81.0 0.0 1.3e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV AAA_13 PF13166.1 CEH14250.1 - 0.092 11.1 2.9 0.11 10.9 2.0 1.0 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CEH14250.1 - 1.8 8.8 8.2 2.4 8.4 5.7 1.1 1 0 0 1 1 1 0 AAA domain Sel1 PF08238.7 CEH14251.1 - 1.9e-13 50.5 20.4 1.9e-05 25.1 0.2 4.7 4 0 0 4 4 4 3 Sel1 repeat Usp PF00582.21 CEH14252.1 - 1.4e-17 64.2 0.1 2.5e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family Toprim_4 PF13662.1 CEH14252.1 - 0.0049 16.8 0.2 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 Toprim domain DNA_photolyase PF00875.13 CEH14252.1 - 0.07 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 DNA photolyase Peptidase_S9 PF00326.16 CEH14255.1 - 4.5e-39 133.8 0.0 8.9e-39 132.9 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CEH14255.1 - 1.2e-13 51.4 0.6 2.9e-13 50.2 0.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH14255.1 - 6.2e-12 45.4 0.1 2.1e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH14255.1 - 6.5e-06 25.8 0.1 3.9e-05 23.3 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 CEH14255.1 - 7.6e-06 25.3 0.1 7.9e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 CEH14255.1 - 0.001 18.5 0.0 0.51 9.7 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 CEH14255.1 - 0.0024 17.4 0.0 0.0058 16.2 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 CEH14255.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PhoPQ_related PF10142.4 CEH14255.1 - 0.09 11.2 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Trypsin_2 PF13365.1 CEH14256.1 - 0.0017 18.3 0.1 0.029 14.3 0.0 2.7 2 1 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S29 PF02907.10 CEH14256.1 - 0.043 13.3 0.3 0.12 11.8 0.2 1.7 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease RNA_pol_Rpb1_1 PF04997.7 CEH14257.1 - 3.6e-107 358.5 0.0 5.4e-107 357.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CEH14257.1 - 1.6e-103 345.7 0.0 2.7e-103 345.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CEH14257.1 - 1.6e-68 229.8 0.0 3e-68 228.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CEH14257.1 - 7.6e-56 188.8 0.0 1.3e-55 188.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 CEH14257.1 - 2.4e-45 154.0 0.0 5.5e-45 152.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 CEH14257.1 - 9.8e-39 132.1 0.4 2e-38 131.1 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 CEH14257.1 - 2e-38 130.4 0.0 4.7e-38 129.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 CEH14257.1 - 7.2e-13 47.4 224.1 0.0076 16.2 6.4 16.2 7 3 13 21 21 21 16 RNA polymerase Rpb1 C-terminal repeat RRM_1 PF00076.17 CEH14258.1 - 4.3e-32 109.5 0.0 1.8e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH14258.1 - 2.2e-26 91.6 0.0 1.3e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH14258.1 - 4.4e-14 52.0 0.0 1.1e-06 28.3 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) POM121 PF15229.1 CEH14259.1 - 0.29 10.5 2.8 0.41 10.0 1.9 1.3 1 0 0 1 1 1 0 POM121 family MRC1 PF09444.5 CEH14261.1 - 3.4e-21 76.1 18.4 3.4e-21 76.1 12.8 6.2 5 2 1 6 6 6 2 MRC1-like domain Cyto_heme_lyase PF01265.12 CEH14262.1 - 1.4e-75 254.2 2.9 2.1e-75 253.6 2.0 1.4 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase SAGA-Tad1 PF12767.2 CEH14263.1 - 4.5e-45 154.2 0.6 3.8e-44 151.2 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit FAM165 PF14981.1 CEH14263.1 - 0.026 14.0 0.8 0.051 13.0 0.6 1.4 1 0 0 1 1 1 0 FAM165 family BPL_N PF09825.4 CEH14264.1 - 1.8e-59 201.4 0.0 4.2e-37 127.8 0.0 2.7 3 0 0 3 3 3 2 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 CEH14264.1 - 1.1e-15 57.7 0.0 2.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.9 CEH14264.1 - 0.07 12.7 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Proteasome PF00227.21 CEH14265.1 - 4.4e-49 166.3 0.2 5.4e-49 166.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CEH14265.1 - 0.089 12.0 0.6 0.4 9.9 0.4 2.0 1 1 0 1 1 1 0 Proteasome beta subunits C terminal DUF4116 PF13475.1 CEH14265.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF2414 PF10309.4 CEH14266.1 - 6.1e-07 29.0 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 CEH14266.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain Cation_efflux PF01545.16 CEH14267.1 - 7.7e-30 103.9 2.6 9.3e-30 103.6 1.8 1.1 1 0 0 1 1 1 1 Cation efflux family DPM2 PF07297.7 CEH14268.1 - 0.11 12.7 0.3 0.23 11.7 0.2 1.5 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Fork_head_N PF08430.7 CEH14268.1 - 2.2 8.7 5.1 1.9 8.9 2.8 1.4 1 1 0 1 1 1 0 Forkhead N-terminal region Asp PF00026.18 CEH14269.1 - 9.4e-38 130.2 0.0 1.5e-37 129.5 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEH14269.1 - 6.2e-12 45.7 0.2 3.1e-11 43.5 0.1 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CEH14269.1 - 5.7e-05 23.5 0.1 1.9 9.0 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 CEH14269.1 - 0.0012 18.6 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 CEH14269.1 - 0.017 15.0 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease PetG PF02529.10 CEH14270.1 - 0.064 12.7 0.9 0.15 11.5 0.1 2.0 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 DUF2415 PF10313.4 CEH14271.1 - 2.9e-06 26.8 0.0 9.4e-06 25.2 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 CEH14271.1 - 1.5e-05 24.6 1.0 0.00018 21.2 0.3 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat PD40 PF07676.7 CEH14271.1 - 0.0018 17.9 0.4 7.8 6.2 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 CEH14271.1 - 0.0037 16.4 0.1 0.018 14.1 0.0 2.0 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.2 CEH14271.1 - 0.0043 16.7 0.1 0.02 14.5 0.0 2.5 1 1 1 2 2 2 1 Transcription factor IIIC subunit delta N-term DPPIV_N PF00930.16 CEH14271.1 - 0.12 10.9 0.0 2.3 6.7 0.0 2.1 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PBP1_TM PF14812.1 CEH14271.1 - 0.36 11.1 9.7 3.2 8.1 3.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAP_alpha PF03896.11 CEH14271.1 - 0.53 9.2 2.2 1 8.2 1.4 1.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 CEH14271.1 - 1.3 8.5 6.2 2.7 7.4 4.0 1.7 2 0 0 2 2 2 0 Nucleoplasmin ArsB PF02040.10 CEH14272.1 - 1.8e-09 37.0 5.1 1.8e-09 37.0 3.6 2.1 2 0 0 2 2 2 1 Arsenical pump membrane protein CitMHS PF03600.11 CEH14272.1 - 1.2e-08 33.9 6.7 1.7e-08 33.4 4.7 1.3 1 0 0 1 1 1 1 Citrate transporter Pkinase PF00069.20 CEH14273.1 - 1e-42 146.1 0.6 1.5e-23 83.2 0.2 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH14273.1 - 3.8e-12 45.8 0.4 9.4e-09 34.7 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CEH14273.1 - 0.22 10.2 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Metallophos_2 PF12850.2 CEH14274.1 - 1.4e-07 31.5 0.1 3.5e-07 30.1 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CEH14274.1 - 4.5e-06 26.1 0.0 2.1e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase CTP_transf_2 PF01467.21 CEH14275.1 - 0.12 12.3 0.0 4 7.4 0.0 2.3 2 0 0 2 2 2 0 Cytidylyltransferase Radical_SAM PF04055.16 CEH14276.1 - 2.4e-11 44.1 0.0 3.8e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Lactamase_B_2 PF12706.2 CEH14278.1 - 9.4e-14 51.4 0.0 2.1e-12 47.0 0.0 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CEH14278.1 - 1.1e-12 48.0 0.8 3e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily F-box-like PF12937.2 CEH14279.1 - 0.038 13.7 0.4 0.07 12.8 0.3 1.4 1 0 0 1 1 1 0 F-box-like Mob_synth_C PF06463.8 CEH14279.1 - 0.068 12.8 0.1 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C Antimicrobial18 PF08130.6 CEH14279.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Type A lantibiotic family Epimerase PF01370.16 CEH14280.1 - 1.2e-18 67.3 0.0 2.3e-18 66.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEH14280.1 - 3.6e-17 62.9 0.1 5.9e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CEH14280.1 - 4.4e-08 32.6 0.0 6.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 CEH14280.1 - 3e-07 29.4 0.0 6.7e-07 28.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CEH14280.1 - 4e-07 29.1 0.0 1.1e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 CEH14280.1 - 5.7e-05 23.0 0.1 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 CEH14280.1 - 0.00017 21.5 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 CEH14280.1 - 0.0015 17.5 1.4 0.011 14.6 1.0 2.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 CEH14280.1 - 0.002 17.8 0.0 0.0052 16.4 0.0 1.7 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 CEH14280.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase tRNA_U5-meth_tr PF05958.6 CEH14281.1 - 6.8e-21 74.3 0.0 8.7e-20 70.6 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 CEH14281.1 - 7.2e-11 41.8 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH14281.1 - 9.5e-07 28.8 0.0 2.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CEH14281.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 CEH14281.1 - 2.5e-05 23.6 0.0 5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 CEH14281.1 - 0.0005 19.7 0.0 0.00095 18.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 CEH14281.1 - 0.00082 19.9 0.0 0.0023 18.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH14281.1 - 0.0012 19.1 0.0 0.0047 17.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH14281.1 - 0.0012 19.2 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 CEH14281.1 - 0.0033 17.1 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 TRAM domain PrmA PF06325.8 CEH14281.1 - 0.0038 16.4 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 CEH14281.1 - 0.0059 15.7 0.0 0.05 12.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CEH14281.1 - 0.013 14.6 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase TPMT PF05724.6 CEH14281.1 - 0.047 13.1 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.14 CEH14281.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Porphobil_deam PF01379.15 CEH14282.1 - 4e-67 225.2 0.0 1.2e-62 210.5 0.0 2.3 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CEH14282.1 - 8e-15 54.7 0.6 2.2e-08 34.0 0.0 3.2 3 0 0 3 3 3 2 Porphobilinogen deaminase, C-terminal domain DUF658 PF04936.7 CEH14282.1 - 0.3 10.9 1.4 0.57 9.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF658) Requiem_N PF14051.1 CEH14283.1 - 0.0033 17.3 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. AT_hook PF02178.14 CEH14284.1 - 8.5 6.4 17.0 0.15 11.8 1.3 4.2 4 0 0 4 4 4 0 AT hook motif NUDIX PF00293.23 CEH14286.1 - 3e-09 36.6 0.0 6.7e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain KH_1 PF00013.24 CEH14290.1 - 3.6e-30 103.3 0.7 2.1e-08 33.7 0.0 6.1 7 0 0 7 7 7 4 KH domain KH_3 PF13014.1 CEH14290.1 - 5.9e-24 83.2 1.3 4.1e-06 26.3 0.0 5.4 5 0 0 5 5 5 4 KH domain HATPase_c_5 PF14501.1 CEH14290.1 - 0.045 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 GHKL domain Pro-kuma_activ PF09286.6 CEH14290.1 - 0.049 13.6 0.1 3.5 7.6 0.0 2.7 2 0 0 2 2 2 0 Pro-kumamolisin, activation domain RhoGAP PF00620.22 CEH14291.1 - 1.3e-46 157.9 2.9 1.6e-46 157.6 0.0 2.5 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.17 CEH14291.1 - 6e-15 55.0 30.1 6.9e-09 35.6 3.4 3.5 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.17 CEH14291.1 - 3.7e-06 26.5 6.6 3.7e-06 26.5 4.6 3.9 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3541 PF12060.3 CEH14291.1 - 0.11 11.7 3.0 0.28 10.4 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) SRR1 PF07985.7 CEH14292.1 - 3e-10 39.8 0.0 6.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 SRR1 Cellulase-like PF12876.2 CEH14292.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF155 PF02582.9 CEH14293.1 - 5.7e-52 176.1 0.0 8.3e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CDC45 PF02724.9 CEH14293.1 - 3.6 5.4 9.8 4.5 5.1 2.4 2.1 2 0 0 2 2 2 0 CDC45-like protein NADH_B2 PF14813.1 CEH14294.1 - 0.011 15.4 0.3 0.014 15.0 0.2 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 MAPEG PF01124.13 CEH14296.1 - 3.7e-24 84.7 1.8 4.3e-24 84.5 1.2 1.0 1 0 0 1 1 1 1 MAPEG family Lipase_GDSL_2 PF13472.1 CEH14298.1 - 3.1e-06 27.4 0.0 4.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CEH14298.1 - 0.00016 21.6 0.0 0.00023 21.0 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LytR_C PF13399.1 CEH14299.1 - 0.0064 16.8 0.1 0.011 16.1 0.1 1.4 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator DUF4015 PF13200.1 CEH14299.1 - 0.12 11.2 0.1 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain CBS PF00571.23 CEH14301.1 - 8.1e-09 35.1 1.5 0.057 13.2 0.0 4.8 5 0 0 5 5 5 2 CBS domain Acetyltransf_1 PF00583.19 CEH14302.1 - 7.4e-18 64.3 0.0 9.6e-18 63.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEH14302.1 - 5.8e-06 26.4 0.0 7.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEH14302.1 - 6e-06 25.9 0.0 8.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CEH14302.1 - 8.5e-05 22.6 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEH14302.1 - 0.00058 19.7 0.1 0.00075 19.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEH14302.1 - 0.0087 16.2 0.0 0.01 16.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CEH14302.1 - 0.027 14.4 0.0 0.031 14.2 0.0 1.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Band_7 PF01145.20 CEH14303.1 - 3e-24 85.8 4.0 3.7e-24 85.6 2.0 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF3290 PF11694.3 CEH14304.1 - 0.11 12.2 1.7 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) SHR3_chaperone PF08229.6 CEH14305.1 - 0.24 10.3 1.0 0.29 10.0 0.1 1.5 2 0 0 2 2 2 0 ER membrane protein SH3 Thioesterase PF00975.15 CEH14306.1 - 7.7e-13 49.1 3.3 4.2e-12 46.7 2.3 2.1 1 1 0 1 1 1 1 Thioesterase domain PCAF_N PF06466.6 CEH14306.1 - 0.0017 17.7 0.8 0.16 11.2 0.0 2.6 3 0 0 3 3 3 2 PCAF (P300/CBP-associated factor) N-terminal domain Glucosamine_iso PF01182.15 CEH14308.1 - 1.6e-53 181.4 0.0 1.9e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NDUF_B12 PF08122.7 CEH14309.1 - 2.4e-15 56.0 1.5 3.2e-15 55.5 0.5 1.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B12 subunit family Inositol_P PF00459.20 CEH14310.1 - 4.9e-70 235.9 0.5 5.6e-70 235.7 0.3 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Cu_amine_oxidN1 PF07833.6 CEH14310.1 - 0.041 14.2 0.1 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Copper amine oxidase N-terminal domain ATP-synt_B PF00430.13 CEH14310.1 - 0.064 13.0 3.3 0.11 12.2 1.3 1.9 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF837 PF05769.6 CEH14313.1 - 1.5e-07 31.1 6.3 2.3e-06 27.2 1.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF837) SpoIIP PF07454.6 CEH14313.1 - 0.021 14.0 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NYD-SP28_assoc PF14775.1 CEH14313.1 - 0.51 10.0 7.9 4.2 7.1 0.2 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF972 PF06156.8 CEH14313.1 - 0.85 9.9 8.6 6 7.2 1.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) SKN1 PF03935.10 CEH14315.1 - 1.4e-175 584.3 0.2 9.8e-174 578.1 0.1 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 CEH14315.1 - 8.4e-07 28.4 0.0 0.0028 16.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 FtsJ PF01728.14 CEH14316.1 - 1.8e-28 99.7 0.0 2.7e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pex24p PF06398.6 CEH14317.1 - 0.00091 18.1 3.9 0.0016 17.3 2.7 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4414 PF14377.1 CEH14318.1 - 7.6e-26 90.1 6.3 7.6e-26 90.1 4.3 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4414) IncA PF04156.9 CEH14318.1 - 0.0087 15.6 3.9 0.027 14.0 2.7 1.9 1 0 0 1 1 1 1 IncA protein Hid1 PF12722.2 CEH14318.1 - 0.23 9.0 4.5 0.45 8.1 3.2 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein APG6 PF04111.7 CEH14318.1 - 1.1 8.2 5.4 2.4 7.1 3.8 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CEH14318.1 - 2 7.9 6.0 5.8 6.4 4.2 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF908 PF06012.7 CEH14319.1 - 7.4e-67 225.9 0.0 1e-65 222.2 0.0 2.4 1 1 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 CEH14319.1 - 1.7e-12 46.8 0.2 7.7e-08 31.4 0.0 3.2 2 1 1 3 3 3 2 Domain of Unknown Function (DUF913) zf-4CXXC_R1 PF10497.4 CEH14322.1 - 7.6e-17 61.3 9.5 1.5e-16 60.4 6.6 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 AT_hook PF02178.14 CEH14322.1 - 0.064 12.9 19.0 0.45 10.3 3.7 3.5 2 0 0 2 2 2 0 AT hook motif PAS_4 PF08448.5 CEH14322.1 - 0.22 11.5 0.0 0.22 11.5 0.0 2.9 2 1 0 2 2 2 0 PAS fold zf-RING_3 PF14369.1 CEH14322.1 - 8.9 6.4 10.1 31 4.6 0.6 2.8 1 1 1 2 2 2 0 zinc-finger SPRY PF00622.23 CEH14324.1 - 5.1e-17 62.1 0.1 7.8e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 SPRY domain IBN_N PF03810.14 CEH14325.1 - 1.9e-07 30.8 0.2 7.3e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain FANCI_S2 PF14676.1 CEH14325.1 - 0.00073 19.4 0.3 0.28 11.0 0.0 2.9 2 1 0 3 3 3 2 FANCI solenoid 2 CAS_CSE1 PF03378.10 CEH14325.1 - 0.052 11.8 0.0 0.092 11.0 0.0 1.3 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus ECH PF00378.15 CEH14329.1 - 9.7e-28 96.9 0.2 1.4e-27 96.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 CEH14330.1 - 4.7e-44 150.3 1.5 5.3e-44 150.1 1.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CEH14330.1 - 0.0081 16.2 0.2 0.019 15.0 0.1 1.6 1 1 1 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Ribosomal_L44 PF00935.14 CEH14331.1 - 0.17 11.9 0.9 0.37 10.8 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L44 Med31 PF05669.7 CEH14334.1 - 3.8e-24 84.3 0.0 4.7e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 SOH1 Bromodomain PF00439.20 CEH14335.1 - 6.2e-33 112.5 0.1 3.1e-17 62.2 0.1 2.6 2 1 0 2 2 2 2 Bromodomain Pkinase PF00069.20 CEH14336.1 - 4.3e-55 186.6 0.1 1.3e-54 185.0 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH14336.1 - 4.2e-17 62.0 0.0 7.1e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH14336.1 - 8.3e-09 35.5 0.0 8.1e-07 29.0 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CEH14336.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 CEH14336.1 - 0.018 14.6 1.5 0.018 14.6 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 CEH14336.1 - 0.022 13.8 0.1 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF382 PF04037.8 CEH14338.1 - 2.4e-56 189.0 0.2 4e-56 188.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 CEH14338.1 - 2.8e-19 68.2 5.4 6.3e-19 67.0 3.7 1.6 1 0 0 1 1 1 1 PSP DNA_pol_phi PF04931.8 CEH14338.1 - 0.045 11.5 16.3 0.071 10.8 11.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi eIF-3c_N PF05470.7 CEH14338.1 - 0.073 11.1 0.5 0.14 10.2 0.3 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FAD_binding_3 PF01494.14 CEH14339.1 - 5.3e-11 42.1 0.9 0.0018 17.4 0.0 3.3 3 0 0 3 3 3 3 FAD binding domain SE PF08491.5 CEH14339.1 - 0.0098 14.7 0.0 2.8 6.6 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase F-box-like PF12937.2 CEH14340.1 - 0.0018 17.9 0.2 0.0043 16.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like Slx4 PF09494.5 CEH14341.1 - 8.4e-13 47.8 0.0 2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease Fimbrial_K88 PF02432.10 CEH14341.1 - 0.0019 17.7 2.3 0.69 9.2 0.2 2.2 2 0 0 2 2 2 2 Fimbrial, major and minor subunit DNA_binding_1 PF01035.15 CEH14341.1 - 0.038 13.7 0.4 11 5.8 0.0 2.7 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Ish1 PF10281.4 CEH14341.1 - 0.12 12.4 0.0 3.9 7.6 0.0 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DNA_pol_A PF00476.15 CEH14342.1 - 1.6e-87 293.6 0.0 7.1e-87 291.5 0.0 2.0 2 1 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 CEH14342.1 - 0.12 11.8 0.1 11 5.5 0.0 3.2 3 0 0 3 3 3 0 3'-5' exonuclease DUF3105 PF11303.3 CEH14343.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) FAD_binding_2 PF00890.19 CEH14345.1 - 8.2e-92 308.2 0.5 1.1e-91 307.8 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 CEH14345.1 - 7.4e-22 76.9 0.3 2.9e-20 71.8 0.0 3.2 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 CEH14345.1 - 1.2e-14 53.9 2.0 1.2e-13 50.7 1.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CEH14345.1 - 2.3e-10 40.1 0.7 6.8e-10 38.5 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CEH14345.1 - 7.1e-10 39.1 0.0 7.1e-08 32.5 0.0 3.3 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH14345.1 - 1.4e-09 37.8 0.1 1.4e-09 37.8 0.0 3.1 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CEH14345.1 - 9.5e-08 31.3 0.5 0.0013 17.6 0.1 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.9 CEH14345.1 - 2.6e-07 29.4 3.9 2.2e-05 23.0 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.1 CEH14345.1 - 2.2e-05 24.6 1.6 5.6e-05 23.3 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CEH14345.1 - 0.00042 19.4 0.3 0.011 14.7 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 CEH14345.1 - 0.0007 18.7 0.7 0.0032 16.5 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CEH14345.1 - 0.0024 18.2 1.7 0.0064 16.8 0.1 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CEH14345.1 - 0.0049 16.4 0.2 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 CEH14345.1 - 0.0066 16.2 0.6 0.11 12.2 0.4 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 CEH14345.1 - 0.031 14.5 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding GDI PF00996.13 CEH14345.1 - 0.072 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.7 CEH14345.1 - 0.083 11.7 0.1 0.24 10.2 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein WD40 PF00400.27 CEH14346.1 - 1.9e-40 135.3 7.0 3.9e-10 39.2 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CEH14346.1 - 6.3e-10 37.8 0.1 0.0032 15.6 0.0 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 CENP-F_leu_zip PF10473.4 CEH14346.1 - 0.42 10.4 8.4 0.7 9.7 5.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pyr_redox PF00070.22 CEH14347.1 - 4.9e-08 33.2 0.0 1.3e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEH14347.1 - 5.8e-07 29.5 0.0 0.021 14.6 0.0 3.9 2 2 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEH14347.1 - 0.0036 17.3 0.4 32 4.4 0.0 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CEH14347.1 - 0.012 14.5 0.1 0.21 10.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CEH14347.1 - 0.019 14.7 0.1 0.057 13.1 0.0 1.8 1 1 1 2 2 2 0 FAD-NAD(P)-binding CheB_methylest PF01339.12 CEH14347.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 CheB methylesterase Eno-Rase_NADH_b PF12242.3 CEH14347.1 - 0.08 12.7 0.2 11 5.8 0.0 3.2 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Med26 PF08711.6 CEH14348.1 - 1.2e-11 43.9 0.3 2.2e-11 43.0 0.1 1.6 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Rgp1 PF08737.5 CEH14349.1 - 2.8e-72 244.0 0.0 4.6e-72 243.3 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 CEH14349.1 - 5.7e-05 22.9 0.0 0.04 13.7 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain IU_nuc_hydro PF01156.14 CEH14350.1 - 1.5e-29 103.2 0.4 1.9e-29 102.8 0.2 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase AAA_11 PF13086.1 CEH14351.1 - 1.3e-26 93.6 0.1 8.3e-16 58.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.1 CEH14351.1 - 1.8e-15 56.8 0.0 8.5e-15 54.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH14351.1 - 2.5e-12 46.3 0.1 2.5e-12 46.3 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 CEH14351.1 - 5.1e-07 29.2 0.0 5.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 CEH14351.1 - 0.00047 19.8 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 Helicase PhoH PF02562.11 CEH14351.1 - 0.00066 18.9 0.0 0.0022 17.2 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.10 CEH14351.1 - 0.0022 17.8 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CEH14351.1 - 0.016 14.6 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase PIF1 PF05970.9 CEH14351.1 - 0.37 9.7 0.0 3.9 6.3 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase F-box PF00646.28 CEH14352.1 - 0.0048 16.5 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain Peptidase_M43 PF05572.8 CEH14355.1 - 4.2e-16 58.9 0.0 9.5e-16 57.7 0.0 1.5 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 CEH14355.1 - 5.2e-09 35.9 0.5 0.00013 21.5 0.0 2.2 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CEH14355.1 - 7.6e-08 32.5 1.3 1.2e-06 28.6 0.9 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 CEH14355.1 - 8.1e-08 32.8 2.0 6.5e-07 29.9 1.4 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CEH14355.1 - 1e-07 32.1 0.1 1.6e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 CEH14355.1 - 0.0019 17.9 1.5 0.012 15.3 1.1 2.0 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 CEH14355.1 - 0.0042 16.0 0.6 0.0074 15.2 0.4 1.3 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M57 PF12388.3 CEH14355.1 - 0.07 12.4 0.5 0.14 11.4 0.1 1.7 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Reprolysin PF01421.14 CEH14355.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Metallopep PF12044.3 CEH14355.1 - 0.09 11.2 1.1 0.15 10.4 0.8 1.3 1 0 0 1 1 1 0 Putative peptidase family DUF1025 PF06262.6 CEH14355.1 - 0.12 12.1 0.2 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Pyr_redox_2 PF07992.9 CEH14356.1 - 1.6e-19 70.5 7.1 6.9e-15 55.4 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 CEH14356.1 - 2.2e-14 52.8 0.0 5.2e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 CEH14356.1 - 5.6e-11 42.6 12.3 6e-10 39.4 1.0 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEH14356.1 - 9e-09 35.6 1.1 6.4e-07 29.6 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CEH14356.1 - 2.6e-05 23.3 0.0 0.62 8.9 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 CEH14356.1 - 0.00031 20.5 0.3 0.076 12.7 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding Reductase_C PF14759.1 CEH14356.1 - 0.01 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 Reductase C-terminal HI0933_like PF03486.9 CEH14356.1 - 0.022 13.2 5.2 0.022 13.2 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 CEH14356.1 - 0.072 12.4 0.2 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GPI-anchored PF10342.4 CEH14358.1 - 7.6e-12 45.5 1.1 7.6e-12 45.5 0.8 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.4 CEH14358.1 - 0.11 11.1 10.4 0.14 10.7 7.2 1.3 1 1 0 1 1 1 0 RAM signalling pathway protein Pex14_N PF04695.8 CEH14358.1 - 9.2 6.3 9.4 2.2 8.3 2.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nuc-transf PF10127.4 CEH14360.1 - 6.5e-16 58.4 0.0 1.2e-15 57.5 0.0 1.4 1 1 0 1 1 1 1 Predicted nucleotidyltransferase NTP_transf_2 PF01909.18 CEH14360.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Na_H_Exchanger PF00999.16 CEH14361.1 - 1.2e-20 73.4 40.6 1.6e-08 33.4 9.5 3.9 3 1 0 3 3 3 3 Sodium/hydrogen exchanger family Sel1 PF08238.7 CEH14363.1 - 1.9e-43 145.8 21.0 1e-07 32.3 0.3 8.8 8 0 0 8 8 8 7 Sel1 repeat DEAD PF00270.24 CEH14364.1 - 6e-24 84.4 0.5 9e-23 80.6 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.1 CEH14364.1 - 0.0019 17.8 0.1 0.11 12.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CEH14364.1 - 0.011 15.5 0.1 0.011 15.5 0.0 3.0 3 0 0 3 3 3 0 Part of AAA domain ResIII PF04851.10 CEH14364.1 - 0.012 15.4 0.0 0.2 11.4 0.0 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SE PF00437.15 CEH14364.1 - 0.018 13.9 0.0 0.054 12.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein KaiC PF06745.8 CEH14364.1 - 0.049 12.7 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC rRNA_proc-arch PF13234.1 CEH14365.1 - 1.7e-77 260.2 0.0 2.5e-77 259.6 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 CEH14365.1 - 5.7e-61 204.8 1.4 5.7e-61 204.8 1.0 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain Cauli_AT PF03233.8 CEH14365.1 - 0.13 11.9 0.4 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Aphid transmission protein TMF_TATA_bd PF12325.3 CEH14365.1 - 2 8.1 10.2 0.28 10.9 0.1 3.7 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 CEH14365.1 - 2.3 8.0 15.9 0.26 11.1 0.9 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CTP_transf_2 PF01467.21 CEH14366.1 - 2.3e-24 86.2 0.0 3.2e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase OTU PF02338.14 CEH14367.1 - 6.9e-06 26.6 0.0 1.9e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease Syntaxin PF00804.20 CEH14367.1 - 0.025 14.7 1.2 0.025 14.7 0.9 2.1 1 1 1 2 2 2 0 Syntaxin Tektin PF03148.9 CEH14367.1 - 0.11 10.9 3.4 0.18 10.3 2.4 1.2 1 0 0 1 1 1 0 Tektin family Seryl_tRNA_N PF02403.17 CEH14367.1 - 0.49 10.4 5.9 1.1 9.3 4.1 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cyt-b5 PF00173.23 CEH14368.1 - 2.8e-19 68.6 0.0 4.3e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain eIF-3_zeta PF05091.7 CEH14370.1 - 6.2e-150 500.2 0.0 2.1e-149 498.4 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAA_hydrolase PF01557.13 CEH14371.1 - 2.1e-44 151.5 0.0 3.1e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HCBP_related PF06594.6 CEH14371.1 - 0.011 15.3 0.0 0.23 11.1 0.0 2.5 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain Rho_GDI PF02115.12 CEH14384.1 - 2e-49 167.7 0.0 2.2e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Oxidored_FMN PF00724.15 CEH14385.1 - 5.2e-48 163.7 0.0 6.5e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Vitelline_membr PF10542.4 CEH14387.1 - 0.11 12.0 0.5 0.18 11.4 0.4 1.5 1 1 0 1 1 1 0 Vitelline membrane cysteine-rich region Nitroreductase PF00881.19 CEH14388.1 - 3.4e-07 30.2 0.1 4.2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Lant_dehyd_N PF04737.8 CEH14389.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus MerC PF03203.9 CEH14389.1 - 0.52 10.6 13.7 0.047 14.0 4.9 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein CENP-B_dimeris PF09026.5 CEH14391.1 - 0.00091 19.4 1.0 0.0024 18.0 0.7 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 CEH14391.1 - 0.086 12.3 1.2 0.19 11.2 0.1 2.0 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 CEH14391.1 - 0.17 12.2 0.2 0.17 12.2 0.1 3.8 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chorion_2 PF03964.10 CEH14391.1 - 9.5 6.8 13.6 57 4.3 9.4 2.4 1 1 0 1 1 1 0 Chorion family 2 ELO PF01151.13 CEH14392.1 - 1.1e-47 162.4 12.5 5.5e-46 156.9 8.7 2.0 1 1 0 1 1 1 1 GNS1/SUR4 family FA_hydroxylase PF04116.8 CEH14392.1 - 0.025 14.9 4.6 0.025 14.9 3.2 1.9 2 1 0 2 2 2 0 Fatty acid hydroxylase superfamily GDA1_CD39 PF01150.12 CEH14395.1 - 6.8e-85 285.1 0.0 2.5e-84 283.2 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family STAG PF08514.6 CEH14396.1 - 7.6e-30 103.0 0.1 2.4e-29 101.4 0.1 1.9 1 0 0 1 1 1 1 STAG domain HEAT PF02985.17 CEH14396.1 - 0.05 13.7 0.2 15 6.0 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat E1-E2_ATPase PF00122.15 CEH14397.1 - 1.2e-26 93.1 0.0 3.6e-26 91.6 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CEH14397.1 - 5.1e-06 26.7 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEH14397.1 - 7.3e-05 23.2 0.1 0.00023 21.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CEH14397.1 - 8.2e-05 22.1 10.0 8.2e-05 22.1 7.0 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus P5-ATPase PF12409.3 CEH14397.1 - 8.3e-05 22.4 1.8 0.00013 21.8 0.1 2.3 2 0 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 CEH14397.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Gas_vesicle_C PF01304.12 CEH14400.1 - 1.3 8.6 3.3 2.4 7.8 2.3 1.4 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain BCAS2 PF05700.6 CEH14402.1 - 3.1e-48 164.1 2.7 4.3e-48 163.6 1.9 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Rhabdo_M1 PF03342.8 CEH14402.1 - 0.03 13.4 1.4 0.081 12.0 1.0 1.8 1 1 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Enkurin PF13864.1 CEH14402.1 - 0.065 13.4 8.1 0.048 13.8 3.5 2.2 2 1 1 3 3 3 0 Calmodulin-binding TSC22 PF01166.13 CEH14402.1 - 0.44 10.5 2.5 0.97 9.4 0.5 2.6 3 0 0 3 3 3 0 TSC-22/dip/bun family DASH_Spc19 PF08287.6 CEH14402.1 - 1 8.9 8.9 2.8 7.5 4.6 2.2 1 1 1 2 2 2 0 Spc19 Pox_A_type_inc PF04508.7 CEH14402.1 - 4.3 7.3 8.7 59 3.8 0.4 4.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF2013 PF09431.5 CEH14403.1 - 5.8e-48 162.2 3.4 9.4e-48 161.5 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) RrnaAD PF00398.15 CEH14404.1 - 1.7e-20 73.1 0.0 5.3e-20 71.5 0.0 1.6 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase ACBP PF00887.14 CEH14405.1 - 8.1e-28 95.9 0.0 1.3e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein PMI_typeI PF01238.16 CEH14406.1 - 1.1e-110 370.1 0.0 1.7e-98 330.0 0.0 2.1 1 1 1 2 2 2 2 Phosphomannose isomerase type I Bombinin PF05298.6 CEH14406.1 - 0.048 13.1 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 Bombinin Methyltransf_31 PF13847.1 CEH14408.1 - 6.8e-11 41.9 0.0 9.5e-11 41.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEH14408.1 - 8.6e-09 34.8 0.1 3.7e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CEH14408.1 - 1.8e-08 34.9 0.0 4.5e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 CEH14408.1 - 5.1e-08 32.7 0.0 7.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 CEH14408.1 - 6.3e-08 32.4 0.0 2e-05 24.3 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain MTS PF05175.9 CEH14408.1 - 8.4e-08 31.7 0.1 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CEH14408.1 - 1.1e-07 32.0 0.0 5.7e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH14408.1 - 2.4e-07 31.1 0.1 5.3e-07 30.0 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH14408.1 - 1.8e-06 28.3 0.0 1.6e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CEH14408.1 - 4.9e-05 22.5 0.0 7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 CEH14408.1 - 0.00048 19.8 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CEH14408.1 - 0.0012 17.7 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_26 PF13659.1 CEH14408.1 - 0.0032 17.4 0.0 0.0048 16.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CEH14408.1 - 0.0034 16.4 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 CEH14408.1 - 0.0042 16.4 0.2 0.0078 15.6 0.1 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 CEH14408.1 - 0.0076 15.4 0.1 0.011 14.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.8 CEH14408.1 - 0.021 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 CheR PF01739.13 CEH14408.1 - 0.12 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.6 CEH14408.1 - 0.12 11.0 0.0 0.38 9.4 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1698) DnaJ PF00226.26 CEH14409.1 - 6.3e-16 57.8 0.4 1.1e-15 57.0 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain CDRT4 PF15213.1 CEH14410.1 - 8.1 6.5 10.6 7.5 6.6 0.9 2.3 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein SDA1 PF05285.7 CEH14411.1 - 1.8e-78 264.1 32.8 1.8e-78 264.1 22.7 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 CEH14411.1 - 3e-18 65.8 0.1 1.2e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 NUC130/3NT domain BATS PF06968.8 CEH14412.1 - 2.8e-26 91.1 0.0 5.9e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 CEH14412.1 - 6.8e-13 49.1 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily U3_assoc_6 PF08640.6 CEH14415.1 - 2.5e-15 55.9 5.9 2.8e-14 52.6 0.7 3.4 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 RecX PF02631.11 CEH14415.1 - 0.015 15.4 0.3 0.051 13.7 0.2 1.9 1 0 0 1 1 1 0 RecX family Pmp3 PF01679.12 CEH14416.1 - 2.7e-26 90.9 5.7 3e-26 90.8 3.9 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 CEH14416.1 - 7.1 6.3 6.5 0.47 10.1 1.2 1.6 2 0 0 2 2 2 0 Conserved TM helix PCI PF01399.22 CEH14417.1 - 3.5e-20 72.2 0.0 1.5e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.1 CEH14417.1 - 0.029 14.1 8.5 11 6.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CEH14417.1 - 0.91 10.2 20.2 3.2 8.5 0.1 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CEH14417.1 - 4.3 7.4 7.3 11 6.0 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S11 PF00411.14 CEH14418.1 - 4.6e-10 39.6 0.1 1.1e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S11 zf-C2H2_jaz PF12171.3 CEH14420.1 - 0.00031 20.8 1.2 0.00051 20.0 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEH14420.1 - 0.00087 19.4 1.9 0.0015 18.6 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Phage_Gp23 PF10669.4 CEH14420.1 - 1.1 9.3 12.4 0.033 14.3 3.4 2.2 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) ATG16 PF08614.6 CEH14421.1 - 0.0021 17.9 2.3 0.0021 17.9 1.6 3.0 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) Spc24 PF08286.6 CEH14421.1 - 0.082 12.6 3.6 0.16 11.6 2.5 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 CorA PF01544.13 CEH14421.1 - 0.16 10.9 2.0 0.26 10.2 1.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cortex-I_coil PF09304.5 CEH14421.1 - 0.19 11.7 2.8 0.42 10.6 2.0 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil Pox_A11 PF05061.8 CEH14421.1 - 0.22 10.5 0.8 0.36 9.8 0.6 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein Phasin_2 PF09361.5 CEH14421.1 - 0.23 11.5 4.1 1.1 9.3 0.3 2.7 2 0 0 2 2 2 0 Phasin protein DUF1664 PF07889.7 CEH14421.1 - 0.45 10.3 1.4 0.83 9.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ADIP PF11559.3 CEH14421.1 - 0.68 9.8 7.1 1.3 8.9 4.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 CEH14421.1 - 1.1 7.0 0.9 1.5 6.5 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sas10 PF09368.5 CEH14424.1 - 3.3e-19 68.8 4.0 3.3e-19 68.8 2.8 2.1 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CEH14424.1 - 5.9e-08 32.7 2.9 6.8e-08 32.6 0.1 2.6 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Cyt-b5 PF00173.23 CEH14425.1 - 1.7e-11 43.7 0.0 2.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FtsJ PF01728.14 CEH14426.1 - 3e-36 125.1 0.0 3.5e-36 124.8 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Histone PF00125.19 CEH14427.1 - 8.2e-31 105.9 0.2 1.3e-30 105.3 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CEH14427.1 - 1.6e-05 24.9 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CEH14427.1 - 0.0056 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CEH14427.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF1769 PF08588.5 CEH14428.1 - 2.5e-16 59.3 0.2 4.9e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) PXA PF02194.10 CEH14429.1 - 4.8e-17 62.1 0.1 4.2e-14 52.5 0.0 3.4 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.7 CEH14429.1 - 7.5e-07 29.2 0.0 4.2e-06 26.8 0.0 2.4 3 0 0 3 3 3 1 Sorting nexin C terminal DHH PF01368.15 CEH14432.1 - 3.6e-08 33.1 0.0 6.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.9 CEH14432.1 - 5.3e-05 23.4 0.1 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain Bac_rhodopsin PF01036.13 CEH14433.1 - 1.1e-47 162.2 18.1 1.4e-47 161.9 12.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein CtnDOT_TraJ PF07863.6 CEH14433.1 - 0.091 13.2 4.1 1.8 9.0 0.1 2.5 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Arteri_Gl PF00951.13 CEH14433.1 - 0.14 11.7 3.1 0.27 10.8 2.2 1.5 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein zf-DHHC PF01529.15 CEH14434.1 - 2.3e-36 124.8 0.0 2.3e-36 124.8 0.0 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase PIG-P PF08510.7 CEH14434.1 - 0.59 9.7 2.8 0.67 9.5 0.7 2.0 2 0 0 2 2 2 0 PIG-P CBS PF00571.23 CEH14435.1 - 1.2e-34 117.8 9.5 1.1e-08 34.7 0.0 5.0 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 CEH14435.1 - 2.5e-05 23.8 0.0 5.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 PB1 domain NYN PF01936.13 CEH14435.1 - 0.023 15.0 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 NYN domain Ribosomal_S27e PF01667.12 CEH14436.1 - 1.1e-29 101.7 3.6 1.3e-29 101.4 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.8 CEH14436.1 - 0.02 14.3 0.2 0.037 13.5 0.1 1.5 1 0 0 1 1 1 0 CSL zinc finger zf-LSD1 PF06943.7 CEH14436.1 - 0.049 13.2 1.7 0.22 11.1 0.2 2.2 2 0 0 2 2 2 0 LSD1 zinc finger DUF3133 PF11331.3 CEH14436.1 - 0.087 12.4 3.2 0.21 11.1 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) zinc_ribbon_4 PF13717.1 CEH14436.1 - 0.2 11.3 1.6 3 7.6 1.1 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CEH14436.1 - 0.31 10.6 2.0 4.2 7.0 1.4 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Brix PF04427.13 CEH14437.1 - 2.9e-36 124.9 0.0 4e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Ribosomal_L17 PF01196.14 CEH14438.1 - 1.5e-33 115.2 0.0 3.4e-24 85.2 0.0 2.7 1 1 1 2 2 2 2 Ribosomal protein L17 LRR_6 PF13516.1 CEH14438.1 - 0.067 13.2 0.1 27 5.2 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich repeat DUF1769 PF08588.5 CEH14439.1 - 1.2e-21 76.4 0.0 2.7e-21 75.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) DSPc PF00782.15 CEH14440.1 - 1.3e-26 92.7 0.0 4.5e-19 68.3 0.0 3.1 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEH14440.1 - 9.1e-05 21.9 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CEH14440.1 - 0.037 14.0 0.0 0.092 12.7 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate Glyco_hydro_72 PF03198.9 CEH14441.1 - 1.1e-87 294.0 0.0 1.4e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CEH14441.1 - 5.7e-14 52.3 0.7 1.2e-13 51.2 0.5 1.6 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 CEH14441.1 - 5.6e-05 22.4 0.1 0.00017 20.8 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chlam_PMP PF02415.12 CEH14441.1 - 0.0013 18.8 2.8 0.012 15.8 1.9 2.8 1 0 0 1 1 1 1 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Glucan_synthase PF02364.10 CEH14442.1 - 0 1370.0 0.0 0 1369.4 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CEH14442.1 - 1.4e-37 128.1 0.0 3.4e-37 126.9 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 UCH PF00443.24 CEH14446.1 - 4.7e-52 176.7 0.0 9.6e-52 175.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEH14446.1 - 2.6e-29 102.6 0.2 7e-23 81.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SNARE PF05739.14 CEH14447.1 - 8.9e-19 66.9 4.0 2.3e-18 65.6 2.8 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 CEH14447.1 - 3.7e-08 33.4 0.3 3.7e-08 33.4 0.2 3.2 1 1 2 3 3 3 1 Syntaxin DUF3708 PF12501.3 CEH14447.1 - 0.0039 17.0 3.6 0.24 11.2 0.2 2.5 2 0 0 2 2 2 2 Phosphate ATP-binding cassette transporter AAA_13 PF13166.1 CEH14447.1 - 0.35 9.2 10.5 0.46 8.8 7.2 1.0 1 0 0 1 1 1 0 AAA domain Peptidase_S64 PF08192.6 CEH14447.1 - 2.6 6.2 10.7 3.6 5.8 7.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 NAD_binding_10 PF13460.1 CEH14448.1 - 1.4e-10 41.4 0.0 2.3e-06 27.7 0.0 3.1 3 0 0 3 3 3 2 NADH(P)-binding Epimerase PF01370.16 CEH14448.1 - 1.4e-07 31.1 0.0 8.2e-05 22.1 0.0 2.9 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CEH14448.1 - 0.016 14.1 0.0 0.75 8.6 0.0 2.9 3 0 0 3 3 3 0 Male sterility protein RmlD_sub_bind PF04321.12 CEH14448.1 - 0.03 13.2 0.0 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 CEH14448.1 - 0.031 12.9 0.0 0.12 10.9 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NDUFA12 PF05071.11 CEH14449.1 - 5.1e-22 78.3 1.3 6.7e-22 77.9 0.9 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4089 PF13318.1 CEH14450.1 - 0.055 13.7 2.8 0.24 11.7 1.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) Kdo PF06293.9 CEH14451.1 - 0.00016 20.7 0.0 0.00036 19.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEH14451.1 - 0.00019 21.2 0.4 0.0012 18.6 0.3 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CEH14451.1 - 0.046 12.8 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain K-box PF01486.12 CEH14451.1 - 0.14 11.9 0.1 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 K-box region Sugar_tr PF00083.19 CEH14452.1 - 1.8e-124 415.7 21.4 1.8e-124 415.7 14.8 1.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH14452.1 - 3.5e-23 81.9 33.3 2.4e-18 65.9 5.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.1 CEH14452.1 - 0.52 10.4 8.8 0.38 10.8 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) 7TM-7TMR_HD PF07698.6 CEH14452.1 - 5.2 6.4 13.7 0.085 12.2 2.5 2.7 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase OPT PF03169.10 CEH14454.1 - 7.3e-120 401.2 38.8 1.7e-119 400.0 26.9 1.5 1 1 0 1 1 1 1 OPT oligopeptide transporter protein 4HBT PF03061.17 CEH14455.1 - 8.8e-09 35.3 0.0 1.6e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 CEH14455.1 - 1.2e-07 32.2 0.0 1.6e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 CEH14455.1 - 0.0005 19.0 0.7 0.035 13.0 0.3 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase DAP10 PF07213.6 CEH14455.1 - 0.19 11.4 0.6 0.71 9.6 0.0 1.9 1 1 1 2 2 2 0 DAP10 membrane protein MFS_1 PF07690.11 CEH14457.1 - 4.1e-07 29.0 17.2 4.1e-07 29.0 11.9 3.6 2 2 0 2 2 2 1 Major Facilitator Superfamily NUDIX PF00293.23 CEH14458.1 - 6.4e-13 48.5 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain OxoDH_E1alpha_N PF12573.3 CEH14458.1 - 0.034 13.6 0.5 0.12 11.9 0.4 1.9 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal adh_short PF00106.20 CEH14459.1 - 4.2e-23 82.0 0.5 2.7e-14 53.4 0.1 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CEH14459.1 - 2.8e-14 53.4 0.0 1.1e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH14459.1 - 1.3e-09 38.0 0.1 2.3e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 KR domain Eno-Rase_NADH_b PF12242.3 CEH14459.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RICTOR_N PF14664.1 CEH14460.1 - 6.5e-70 235.5 0.1 1.1e-69 234.8 0.1 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 CEH14460.1 - 1.2e-69 233.7 0.0 9.2e-69 230.9 0.0 2.4 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 CEH14460.1 - 1.3e-27 95.9 0.0 1.3e-26 92.8 0.0 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 CEH14460.1 - 1.4e-27 95.4 2.9 1.3e-26 92.3 0.1 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 CEH14460.1 - 4.1e-09 36.0 0.0 1.6e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.17 CEH14460.1 - 0.00056 19.7 2.7 0.19 11.9 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Med12-PQL PF12144.3 CEH14460.1 - 0.026 13.9 1.2 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic Mediator 12 catenin-binding domain HEAT_EZ PF13513.1 CEH14460.1 - 0.14 12.6 13.2 1.5 9.3 0.1 5.7 6 0 0 6 6 6 0 HEAT-like repeat ABC_membrane PF00664.18 CEH14461.1 - 3.8e-43 147.8 6.2 4.9e-43 147.5 4.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CEH14461.1 - 9.4e-33 113.4 0.0 2.7e-32 111.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 CEH14461.1 - 2.1e-05 24.5 0.7 7.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.4 CEH14461.1 - 0.0021 16.7 0.0 0.0034 16.0 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SMC_N PF02463.14 CEH14461.1 - 0.003 16.8 0.1 0.017 14.3 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CEH14461.1 - 0.0099 15.8 0.1 0.034 14.1 0.0 1.7 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 CEH14461.1 - 0.082 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UDPGP PF01704.13 CEH14462.1 - 5.4e-45 153.6 0.0 7.4e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CEH14462.1 - 0.001 19.2 0.0 0.0039 17.2 0.0 2.0 2 0 0 2 2 2 1 MobA-like NTP transferase domain ORC5_C PF14630.1 CEH14463.1 - 1.9e-45 155.4 0.3 2.6e-45 154.9 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus DUF2890 PF11081.3 CEH14464.1 - 0.048 13.7 12.3 0.079 13.0 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TFIIF_alpha PF05793.7 CEH14464.1 - 0.097 11.0 14.1 0.13 10.5 9.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 CEH14464.1 - 0.097 10.6 14.8 0.14 10.1 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 CEH14464.1 - 0.1 11.9 3.4 0.14 11.5 2.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.10 CEH14464.1 - 0.64 8.5 1.8 0.7 8.4 1.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 CEH14464.1 - 0.72 7.6 24.3 1 7.1 16.8 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 CEH14464.1 - 0.77 9.0 14.1 1.1 8.5 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 CEH14464.1 - 0.91 7.9 21.7 1.3 7.4 15.0 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 CEH14464.1 - 3.5 6.8 23.0 5.1 6.2 16.0 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.7 CEH14464.1 - 7 5.8 16.4 10 5.2 11.3 1.2 1 0 0 1 1 1 0 NOA36 protein Mpp10 PF04006.7 CEH14464.1 - 9.7 4.4 19.4 13 3.9 13.4 1.1 1 0 0 1 1 1 0 Mpp10 protein Pkinase PF00069.20 CEH14465.1 - 1.5e-73 247.1 0.0 1.8e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH14465.1 - 2.3e-36 125.1 0.0 3.1e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH14465.1 - 0.00053 19.0 0.0 0.0013 17.8 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CEH14465.1 - 0.01 15.6 0.0 0.14 11.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CEH14465.1 - 0.095 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 CEH14465.1 - 0.1 11.6 0.2 0.23 10.5 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CDP-OH_P_transf PF01066.16 CEH14467.1 - 4.7e-17 62.1 2.0 9.4e-17 61.1 1.4 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Trehalase PF01204.13 CEH14468.1 - 6.6e-169 562.8 4.0 8.2e-169 562.5 2.8 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CEH14468.1 - 1e-14 53.5 0.2 2.1e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Metallophos PF00149.23 CEH14469.1 - 5e-07 29.3 0.0 1.1e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF4112 PF13430.1 CEH14470.1 - 1.4e-24 86.0 0.9 1.9e-24 85.6 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) MIT PF04212.13 CEH14471.1 - 0.0024 17.7 0.1 0.0069 16.2 0.0 1.7 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain GST_N_3 PF13417.1 CEH14472.1 - 4.1e-21 74.9 0.0 8e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEH14472.1 - 6.1e-14 51.7 0.0 1.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CEH14472.1 - 0.012 15.4 0.1 0.024 14.5 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEH14472.1 - 0.021 15.3 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DNA_pol_B_thumb PF14791.1 CEH14473.1 - 2.2e-07 30.4 0.2 0.0091 15.6 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase beta thumb Herpes_gE PF02480.11 CEH14474.1 - 0.0046 15.2 0.0 0.0073 14.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CEH14474.1 - 0.033 14.5 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain gpUL132 PF11359.3 CEH14474.1 - 0.063 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Syndecan PF01034.15 CEH14474.1 - 0.17 11.5 1.0 0.33 10.6 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain CD34_antigen PF06365.7 CEH14474.1 - 0.27 10.8 0.0 0.43 10.2 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family SieB PF14163.1 CEH14474.1 - 0.27 10.7 0.0 0.41 10.2 0.0 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B SKG6 PF08693.5 CEH14474.1 - 0.43 9.9 6.2 0.79 9.0 4.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-C3HC4_3 PF13920.1 CEH14475.1 - 1.3e-09 37.5 5.3 2e-09 36.9 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH14475.1 - 9.2e-07 28.4 5.4 1.5e-06 27.7 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH14475.1 - 1.5e-05 24.8 5.9 2.8e-05 24.0 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEH14475.1 - 6.3e-05 22.7 6.2 0.00011 22.0 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CEH14475.1 - 0.0004 20.0 4.6 0.00068 19.3 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 CEH14475.1 - 0.058 12.9 1.6 0.13 11.8 1.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CEH14475.1 - 0.71 9.8 4.4 2 8.3 3.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING XRN_N PF03159.13 CEH14476.1 - 1.3e-106 355.2 0.0 1.3e-106 355.2 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 CEH14476.1 - 0.0023 17.7 6.7 0.0043 16.9 4.7 1.4 1 0 0 1 1 1 1 Zinc knuckle ATP-synt_DE_N PF02823.11 CEH14477.1 - 4.4e-20 71.2 0.0 6.2e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DnaB_bind PF10410.4 CEH14477.1 - 0.52 10.3 2.6 2.6 8.0 1.0 2.5 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Glyco_transf_28 PF03033.15 CEH14478.1 - 6.4e-25 87.5 0.0 1.5e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CEH14478.1 - 2.9e-17 61.9 0.3 2e-09 36.8 0.0 3.2 3 0 0 3 3 3 2 GRAM domain PH PF00169.24 CEH14478.1 - 2.4e-07 30.9 0.0 1e-06 28.9 0.0 2.2 2 0 0 2 2 2 1 PH domain UDPGT PF00201.13 CEH14478.1 - 0.00099 17.7 0.0 0.0016 17.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.1 CEH14478.1 - 0.0034 17.6 0.0 0.0074 16.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Glyco_tran_28_C PF04101.11 CEH14478.1 - 0.29 10.7 0.0 0.66 9.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain TruD PF01142.13 CEH14479.1 - 7.4e-51 172.9 0.0 1.3e-47 162.3 0.0 3.9 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) ESR1_C PF12743.2 CEH14480.1 - 0.28 10.7 3.3 0.48 10.0 2.3 1.3 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal LSM PF01423.17 CEH14482.1 - 1.5e-15 56.5 0.1 1.9e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain ATP-synt_G PF04718.10 CEH14484.1 - 9.9e-20 71.1 0.8 2.6e-19 69.8 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit SSI PF00720.12 CEH14484.1 - 0.035 14.0 0.7 0.057 13.3 0.5 1.3 1 0 0 1 1 1 0 Subtilisin inhibitor-like Abhydrolase_6 PF12697.2 CEH14485.1 - 2e-09 37.6 0.5 2e-09 37.6 0.3 2.7 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH14485.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH14485.1 - 0.017 14.6 0.0 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Pkinase PF00069.20 CEH14486.1 - 3.2e-53 180.5 0.0 5.8e-53 179.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH14486.1 - 7.8e-20 71.0 0.9 9e-20 70.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CEH14486.1 - 0.0028 17.4 4.0 0.0061 16.3 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CEH14486.1 - 0.098 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2740 PF10872.3 CEH14486.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) zf-CCHC PF00098.18 CEH14487.1 - 6.8e-15 54.1 19.8 0.0001 22.0 1.8 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 CEH14487.1 - 1.4e-07 30.8 12.1 0.014 14.9 0.0 3.8 3 1 1 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 CEH14487.1 - 7.3e-07 28.7 19.3 0.015 14.9 0.4 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_3 PF13917.1 CEH14487.1 - 7 6.4 14.7 6.7 6.5 0.4 4.5 3 1 1 4 4 4 0 Zinc knuckle EF_TS PF00889.14 CEH14488.1 - 1.4e-13 50.6 0.0 4.5e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor TS Y_phosphatase2 PF03162.8 CEH14489.1 - 4.6e-22 78.1 0.0 2.8e-21 75.5 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family DinB PF05163.7 CEH14490.1 - 0.0015 18.2 0.2 0.0039 16.9 0.2 1.6 1 0 0 1 1 1 1 DinB family VPS9 PF02204.13 CEH14490.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain Sugar_tr PF00083.19 CEH14491.1 - 5.6e-56 190.0 11.1 9.3e-56 189.2 7.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH14491.1 - 2.5e-20 72.5 26.3 2.5e-20 72.5 18.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_16 PF10294.4 CEH14492.1 - 1.8e-21 76.3 0.0 8.3e-14 51.4 0.0 3.0 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CEH14492.1 - 0.003 18.1 0.2 0.013 16.1 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH14492.1 - 0.031 14.0 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CEH14492.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Actin PF00022.14 CEH14493.1 - 2e-91 306.3 0.0 2.4e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 Actin CRC_subunit PF08624.5 CEH14494.1 - 5.8e-40 136.4 0.0 9.8e-40 135.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Abhydrolase_6 PF12697.2 CEH14495.1 - 0.0033 17.3 0.1 0.0078 16.1 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CEH14495.1 - 0.11 12.0 0.1 0.53 9.8 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Carn_acyltransf PF00755.15 CEH14497.1 - 6.3e-126 420.8 0.0 2.4e-125 418.9 0.0 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase CGI-121 PF08617.5 CEH14498.1 - 1.5e-29 102.7 0.0 1.9e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 MFS_1 PF07690.11 CEH14500.1 - 3.2e-21 75.4 42.5 1.1e-13 50.6 11.9 3.2 1 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.15 CEH14500.1 - 0.0098 13.9 6.3 0.0043 15.1 2.5 1.7 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Defensin_propep PF00879.13 CEH14500.1 - 0.033 14.1 0.8 0.86 9.5 1.0 2.6 2 0 0 2 2 2 0 Defensin propeptide MFS_1_like PF12832.2 CEH14500.1 - 0.12 12.1 2.6 0.46 10.3 0.1 2.7 2 0 0 2 2 2 0 MFS_1 like family MS_channel PF00924.13 CEH14501.1 - 2.7e-17 62.8 0.2 5.1e-17 61.8 0.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CEH14501.1 - 0.01 15.0 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 CEH14501.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain NAD_binding_4 PF07993.7 CEH14502.1 - 4.2e-12 45.5 0.2 1e-09 37.6 0.1 2.9 2 1 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 CEH14502.1 - 5.6e-12 45.5 0.1 8.5e-12 45.0 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CEH14502.1 - 3.2e-11 42.4 0.0 1e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CEH14502.1 - 0.12 11.5 0.1 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Glyco_hydro_2 PF00703.16 CEH14504.1 - 0.00048 20.5 0.0 0.0014 19.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 CEH14504.1 - 0.019 14.4 0.0 0.06 12.8 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain DUF1897 PF09005.5 CEH14504.1 - 0.03 13.7 2.2 0.07 12.5 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) Sugar_tr PF00083.19 CEH14505.1 - 5.1e-78 262.6 19.8 6.8e-78 262.2 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH14505.1 - 1.8e-14 53.2 25.7 2.7e-14 52.6 17.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OrfB_Zn_ribbon PF07282.6 CEH14506.1 - 0.064 12.9 0.7 0.12 12.0 0.1 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 CEH14506.1 - 0.21 11.5 0.7 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 CEH14506.1 - 0.28 10.4 0.9 11 5.3 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 CEH14506.1 - 1.7 8.4 4.2 5.8 6.6 2.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Acetyltransf_1 PF00583.19 CEH14507.1 - 1.6e-12 47.2 0.0 2.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEH14507.1 - 1.5e-07 31.5 0.0 2.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CEH14507.1 - 1.5e-05 25.0 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEH14507.1 - 0.0098 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 CEH14507.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Mpv17_PMP22 PF04117.7 CEH14508.1 - 1.6e-25 88.5 0.5 2.8e-25 87.7 0.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family PWWP PF00855.12 CEH14511.1 - 2.1e-16 59.8 0.1 2.1e-16 59.8 0.1 2.3 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.6 CEH14511.1 - 0.00025 20.4 0.0 0.00047 19.6 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF2201_N PF13203.1 CEH14511.1 - 1.8 7.6 7.4 2.6 7.1 5.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Lipase_3 PF01764.20 CEH14512.1 - 1.4e-11 44.1 0.0 3.1e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) Sugar_tr PF00083.19 CEH14513.1 - 1.9e-107 359.6 22.1 2.3e-107 359.3 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH14513.1 - 2.5e-13 49.4 37.6 3.6e-13 48.9 8.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.1 CEH14513.1 - 0.0049 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF4091 PF13320.1 CEH14514.1 - 0.072 12.9 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) DAHP_synth_1 PF00793.15 CEH14515.1 - 3.7e-89 298.0 0.0 7.8e-89 296.9 0.0 1.5 1 0 0 1 1 1 1 DAHP synthetase I family Aldedh PF00171.17 CEH14515.1 - 1.7e-14 53.0 0.1 2.5e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 Aldehyde dehydrogenase family Fanconi_A PF03511.9 CEH14516.1 - 0.14 11.9 0.1 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Fanconi anaemia group A protein MFS_1 PF07690.11 CEH14517.1 - 3.4e-22 78.6 37.7 2.5e-18 65.9 8.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH14517.1 - 1.3e-05 24.0 4.8 1.3e-05 24.0 3.3 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter GMC_oxred_N PF00732.14 CEH14518.1 - 1.6e-59 201.4 0.0 2.4e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CEH14518.1 - 1.2e-33 116.4 0.3 2.4e-33 115.4 0.2 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CEH14518.1 - 1.3e-05 24.2 0.7 0.024 13.5 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CEH14518.1 - 0.0015 18.5 0.6 0.0054 16.7 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CEH14518.1 - 0.0021 18.1 0.1 0.034 14.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEH14518.1 - 0.0026 16.7 0.2 0.0047 15.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CEH14518.1 - 0.0051 15.9 0.1 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CEH14518.1 - 0.01 14.8 6.7 0.017 14.0 3.3 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CEH14518.1 - 0.038 12.4 1.5 0.46 8.8 0.1 2.6 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_2 PF07992.9 CEH14518.1 - 0.07 13.0 0.1 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEH14518.1 - 0.17 12.3 0.7 1.8 9.0 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gar1 PF04410.9 CEH14521.1 - 1.8e-35 121.6 3.4 3.8e-35 120.6 0.0 2.0 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Fip1 PF05182.8 CEH14522.1 - 4.7e-18 64.1 3.2 8.2e-18 63.4 2.2 1.3 1 0 0 1 1 1 1 Fip1 motif Pkinase PF00069.20 CEH14524.1 - 3.1e-64 216.6 0.0 5.3e-64 215.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH14524.1 - 2.2e-33 115.4 0.0 3.1e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH14524.1 - 2.2e-08 33.3 0.0 3.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEH14524.1 - 0.00084 19.1 0.6 0.002 17.9 0.4 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CEH14524.1 - 0.0042 16.1 0.1 0.0082 15.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CEH14524.1 - 0.064 12.5 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 RIO1 family LAG1-DNAbind PF09271.6 CEH14525.1 - 4.5e-34 117.9 0.0 1e-33 116.7 0.0 1.6 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 CEH14525.1 - 7.7e-18 64.7 0.0 2.6e-16 59.7 0.0 2.9 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain TIG PF01833.19 CEH14525.1 - 0.00013 21.8 0.1 0.00046 20.1 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain Dynein_heavy PF03028.10 CEH14527.1 - 2.8e-164 547.9 0.0 5.8e-164 546.9 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 CEH14527.1 - 1.7e-43 148.7 8.2 2.8e-43 148.0 5.7 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CEH14527.1 - 3.9e-43 146.9 0.0 1.5e-42 144.9 0.0 2.1 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 CsgE PF10627.4 CEH14528.1 - 0.18 11.6 2.0 0.67 9.7 1.4 1.9 1 0 0 1 1 1 0 Curli assembly protein CsgE PQ-loop PF04193.9 CEH14529.1 - 1.3e-27 95.0 4.5 7.4e-13 47.8 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat Herpes_UL47 PF03362.8 CEH14529.1 - 0.035 12.4 0.2 0.17 10.2 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus UL47 protein NAD_binding_8 PF13450.1 CEH14530.1 - 6.6e-12 45.2 0.0 2e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CEH14530.1 - 0.00063 19.5 0.2 0.0085 15.8 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 CEH14530.1 - 0.0045 16.1 0.1 0.56 9.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 CEH14530.1 - 0.022 13.8 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 CEH14530.1 - 0.026 14.9 0.0 0.077 13.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cyclin_N PF00134.18 CEH14531.1 - 3e-06 26.8 0.0 0.00099 18.6 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF1744 PF08490.7 CEH14532.1 - 1.2e-109 366.5 0.0 1.7e-109 366.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CEH14532.1 - 5.4e-64 216.0 0.0 8.2e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CEH14532.1 - 1e-18 67.4 0.0 1.5e-17 63.5 0.0 2.5 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CEH14532.1 - 1.1e-10 41.3 0.0 3.3e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CEH14532.1 - 2.3e-05 24.2 0.1 0.00016 21.5 0.0 2.5 1 1 0 1 1 1 1 RNase_H superfamily Hexokinase_2 PF03727.11 CEH14533.1 - 1.9e-68 230.3 0.1 2.5e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CEH14533.1 - 6.2e-66 221.6 0.0 9.2e-66 221.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase ATP_synt_I PF03899.10 CEH14533.1 - 0.094 12.8 0.1 9 6.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase I chain RRP7 PF12923.2 CEH14534.1 - 8.2e-29 100.2 2.3 8.2e-29 100.2 1.6 2.1 2 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 CEH14534.1 - 1.2e-05 24.8 0.0 0.00025 20.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH14534.1 - 0.0012 18.8 0.1 0.089 12.7 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L30_N PF08079.7 CEH14535.1 - 3.9e-24 84.4 17.9 7.2e-24 83.5 12.4 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 CEH14535.1 - 1.3e-18 66.2 1.5 2.5e-18 65.3 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF2413 PF10310.4 CEH14536.1 - 1.2e-47 162.7 0.7 3.4e-46 157.9 0.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) CLTH PF10607.4 CEH14537.1 - 1.5e-31 109.0 0.0 2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CEH14537.1 - 5e-09 35.6 0.5 1.2e-08 34.3 0.1 1.8 2 0 0 2 2 2 1 LisH Methyltransf_16 PF10294.4 CEH14538.1 - 3.8e-13 49.2 0.0 8.4e-13 48.1 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CEH14538.1 - 3.9e-05 24.1 0.0 0.0001 22.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH14538.1 - 0.00017 21.3 0.0 0.00037 20.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH14538.1 - 0.0004 20.8 0.0 0.001 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH14538.1 - 0.0058 16.2 0.0 0.015 14.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 CEH14538.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G SBP_bac_5 PF00496.17 CEH14538.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle PCMT PF01135.14 CEH14538.1 - 0.18 11.3 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ODC_AZ PF02100.12 CEH14539.1 - 2e-15 56.2 0.0 3.1e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme CD24 PF14984.1 CEH14539.1 - 0.45 10.3 5.4 0.17 11.7 0.5 2.7 2 0 0 2 2 2 0 CD24 protein UQ_con PF00179.21 CEH14540.1 - 1.8e-51 173.2 0.0 2.1e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEH14540.1 - 3.1e-05 23.7 0.0 3.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CEH14540.1 - 0.00065 19.5 0.0 0.00073 19.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CEH14540.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Med8 PF10232.4 CEH14541.1 - 3.1 7.2 7.5 0.43 10.0 0.1 2.6 2 1 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 MFS_1 PF07690.11 CEH14542.1 - 4.8e-38 130.7 43.4 1.8e-36 125.6 29.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH14542.1 - 1.4e-12 46.9 9.3 1.4e-12 46.9 6.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CEH14542.1 - 8.6e-10 37.4 11.4 1.9e-09 36.3 7.5 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UDP-g_GGTase PF06427.6 CEH14543.1 - 5.1e-51 172.9 0.0 8.1e-51 172.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 CEH14543.1 - 1.1e-06 28.1 0.2 2.2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 DIL PF01843.14 CEH14545.1 - 3.1e-24 84.8 0.9 5.9e-24 83.9 0.6 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 CEH14545.1 - 5.1e-17 61.9 0.0 1.4e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CEH14545.1 - 2e-14 52.5 0.1 3e-07 29.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CEH14545.1 - 1.8e-11 44.2 0.1 1.9e-05 25.0 0.0 3.6 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CEH14545.1 - 2.8e-11 43.2 0.1 8.6e-07 29.0 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH14545.1 - 4e-09 35.8 0.0 8.8e-05 22.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat DUF883 PF05957.8 CEH14547.1 - 0.0021 18.3 4.0 0.0021 18.3 2.8 1.7 2 0 0 2 2 1 1 Bacterial protein of unknown function (DUF883) CRISPR_Cse1 PF09481.5 CEH14547.1 - 0.0036 16.1 0.7 0.0041 15.9 0.5 1.2 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) Rtf2 PF04641.7 CEH14547.1 - 0.024 13.8 0.3 0.028 13.6 0.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Borrelia_P83 PF05262.6 CEH14547.1 - 0.03 12.6 5.0 0.037 12.2 3.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4337 PF14235.1 CEH14547.1 - 0.036 13.8 6.8 0.065 13.0 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) EAP30 PF04157.11 CEH14547.1 - 0.11 11.6 1.4 0.14 11.2 1.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family DUF1484 PF07363.6 CEH14547.1 - 0.15 12.3 0.9 14 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) ISG65-75 PF11727.3 CEH14547.1 - 0.29 10.1 7.1 0.4 9.6 4.9 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein NARP1 PF12569.3 CEH14547.1 - 0.36 9.5 5.9 0.47 9.1 4.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 CEH14547.1 - 0.79 9.5 3.5 0.93 9.3 2.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP-synt_B PF00430.13 CEH14547.1 - 0.93 9.3 12.1 1.5 8.5 8.4 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) YdfA_immunity PF12127.3 CEH14547.1 - 1.4 7.7 5.3 1.8 7.3 3.2 1.5 2 0 0 2 2 2 0 SigmaW regulon antibacterial DUF3987 PF13148.1 CEH14547.1 - 4.9 5.6 9.4 6.9 5.1 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) UcrQ PF02939.11 CEH14548.1 - 2e-23 82.0 0.6 2.3e-23 81.7 0.4 1.0 1 0 0 1 1 1 1 UcrQ family OAS1_C PF10421.4 CEH14549.1 - 0.00021 20.8 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NTP_transf_2 PF01909.18 CEH14549.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain SPT2 PF08243.6 CEH14550.1 - 3.2e-14 53.2 19.9 3.2e-14 53.2 13.8 4.9 4 2 2 6 6 6 1 SPT2 chromatin protein p450 PF00067.17 CEH14552.1 - 2.1e-34 118.8 0.0 3e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Syntaxin-6_N PF09177.6 CEH14555.1 - 1.5e-18 66.9 2.0 1.9e-18 66.6 0.1 2.0 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 CEH14555.1 - 6e-11 41.8 1.2 1.7e-10 40.4 0.3 2.1 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.4 CEH14555.1 - 8.5e-06 25.3 0.1 4.2e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Membrane fusion protein Use1 DUF3584 PF12128.3 CEH14555.1 - 0.0039 14.5 4.0 0.0052 14.1 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HisKA_3 PF07730.8 CEH14555.1 - 0.0089 16.3 4.1 0.7 10.2 0.3 2.6 2 0 0 2 2 2 2 Histidine kinase PhageMin_Tail PF10145.4 CEH14555.1 - 0.089 12.4 1.5 1.7 8.2 0.1 2.1 2 0 0 2 2 2 0 Phage-related minor tail protein PspA_IM30 PF04012.7 CEH14555.1 - 0.15 11.4 3.8 1.4 8.1 0.1 2.2 1 1 1 2 2 2 0 PspA/IM30 family FliJ PF02050.11 CEH14555.1 - 0.3 11.1 3.1 0.67 10.0 0.2 2.6 3 1 0 3 3 3 0 Flagellar FliJ protein DUF1843 PF08898.5 CEH14555.1 - 0.47 10.5 0.2 0.47 10.5 0.1 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) Tropomyosin PF00261.15 CEH14555.1 - 1.2 8.1 4.7 0.83 8.6 0.3 2.3 1 1 1 2 2 2 0 Tropomyosin FKBP_C PF00254.23 CEH14556.1 - 6.7e-34 115.7 0.0 1.1e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DNA_mis_repair PF01119.14 CEH14557.1 - 8.8e-30 102.6 0.0 1.5e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CEH14557.1 - 2.4e-10 40.1 0.0 6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CEH14557.1 - 3.4e-10 39.6 0.0 6.4e-09 35.5 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CCCH PF00642.19 CEH14558.1 - 1.3e-06 27.9 5.2 2.6e-06 26.9 3.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1556 PF07590.6 CEH14558.1 - 0.056 13.6 0.2 0.056 13.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) Ferric_reduct PF01794.14 CEH14560.1 - 8.6e-23 80.7 9.2 8.6e-23 80.7 6.4 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CEH14560.1 - 3.8e-08 33.3 0.0 7.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CEH14560.1 - 4.5e-08 32.9 0.0 9.7e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain AAA PF00004.24 CEH14561.1 - 1e-41 142.1 0.0 2e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 CEH14561.1 - 1.9e-20 72.4 5.2 5.4e-20 71.0 3.6 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.5 CEH14561.1 - 9.6e-08 31.8 0.0 5.7e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 CEH14561.1 - 1.1e-05 25.5 0.1 0.0012 19.0 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CEH14561.1 - 2.8e-05 24.9 0.1 9.8e-05 23.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CEH14561.1 - 3.4e-05 23.3 0.0 6.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 CEH14561.1 - 5e-05 23.0 0.0 0.00016 21.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CEH14561.1 - 5.9e-05 21.9 0.0 0.00016 20.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 CEH14561.1 - 0.00011 22.0 0.0 0.0004 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEH14561.1 - 0.00012 22.1 0.0 0.0016 18.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CEH14561.1 - 0.00012 21.1 0.0 0.00022 20.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CEH14561.1 - 0.00017 21.4 0.0 0.00078 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CEH14561.1 - 0.00018 20.9 0.2 0.052 12.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 CEH14561.1 - 0.00055 20.0 0.0 0.016 15.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 CEH14561.1 - 0.0017 17.3 0.0 0.0033 16.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 CEH14561.1 - 0.0033 17.3 0.0 0.0087 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CEH14561.1 - 0.017 14.8 0.1 0.056 13.2 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain Mg_chelatase PF01078.16 CEH14561.1 - 0.019 14.1 0.0 0.048 12.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CEH14561.1 - 0.02 14.5 0.2 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CEH14561.1 - 0.025 14.2 0.3 0.73 9.4 0.0 2.8 2 1 0 3 3 3 0 Archaeal ATPase AAA_18 PF13238.1 CEH14561.1 - 0.026 14.8 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CEH14561.1 - 0.032 13.3 0.0 2.4 7.1 0.0 2.5 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.21 CEH14561.1 - 0.039 13.4 0.0 0.39 10.1 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 CEH14561.1 - 0.042 12.9 0.1 0.85 8.6 0.0 2.4 1 1 1 2 2 2 0 Zeta toxin NACHT PF05729.7 CEH14561.1 - 0.056 13.0 0.0 0.39 10.3 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.1 CEH14561.1 - 0.073 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CEH14561.1 - 0.077 12.2 0.3 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 CEH14561.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit EH_Signature PF15611.1 CEH14561.1 - 0.14 11.2 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 EH_Signature domain LNP1 PF15419.1 CEH14562.1 - 0.15 12.1 5.1 0.21 11.6 3.5 1.1 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 TPPII_N PF12583.3 CEH14562.1 - 0.27 11.3 7.5 0.36 10.9 5.2 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Draxin PF15550.1 CEH14562.1 - 1.2 8.7 5.0 1.4 8.4 3.5 1.1 1 0 0 1 1 1 0 Draxin BRF1 PF07741.8 CEH14562.1 - 2.8 8.2 9.8 86 3.4 6.8 2.1 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Serglycin PF04360.7 CEH14563.1 - 5.8 6.6 14.8 2.6 7.7 0.1 2.4 1 1 1 2 2 2 0 Serglycin Apc1 PF12859.2 CEH14564.1 - 2.1e-10 40.7 0.6 7.1e-10 39.0 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 Spt4 PF06093.8 CEH14565.1 - 5e-26 90.3 0.2 5.9e-26 90.1 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger WD40 PF00400.27 CEH14566.1 - 4.5e-66 216.5 27.0 4.4e-14 51.7 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CEH14566.1 - 0.00082 18.8 0.2 1.9 8.0 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 CEH14566.1 - 0.14 11.8 0.9 3.1 7.5 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat FRG1 PF06229.7 CEH14567.1 - 2.2e-14 53.3 0.3 7.2e-14 51.6 0.0 2.0 2 1 0 2 2 2 1 FRG1-like family XPG_N PF00752.12 CEH14569.1 - 2.5e-32 111.1 0.0 4.9e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CEH14569.1 - 1.1e-28 99.1 0.0 2e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CEH14569.1 - 2.2e-07 31.0 0.0 5.6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF4192 PF13830.1 CEH14569.1 - 0.14 11.7 0.5 0.33 10.5 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) CENP-K PF11802.3 CEH14570.1 - 8.9e-17 61.2 4.6 8.4e-15 54.7 3.2 2.5 1 1 0 1 1 1 1 Centromere-associated protein K Rsd_AlgQ PF04353.8 CEH14570.1 - 0.0042 16.8 0.5 0.0086 15.7 0.4 1.5 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ APG6 PF04111.7 CEH14570.1 - 0.078 12.0 4.9 0.061 12.3 2.3 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 Hemerythrin PF01814.18 CEH14570.1 - 0.18 11.9 3.0 0.4 10.8 0.1 2.8 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Reo_sigmaC PF04582.7 CEH14570.1 - 0.22 10.6 1.9 0.39 9.8 1.3 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Selenoprotein_S PF06936.6 CEH14570.1 - 0.25 10.8 5.0 0.43 10.0 3.4 1.4 1 1 0 1 1 1 0 Selenoprotein S (SelS) Baculo_PEP_C PF04513.7 CEH14570.1 - 0.65 9.8 13.9 16 5.3 6.2 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 CEH14570.1 - 1.1 8.8 15.7 3.3 7.2 6.0 2.9 1 1 2 3 3 3 0 IncA protein Nefa_Nip30_N PF10187.4 CEH14570.1 - 1.1 9.4 9.7 0.17 12.0 4.0 1.7 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Tubulin_3 PF14881.1 CEH14571.1 - 3.3e-19 69.0 2.6 2.2e-18 66.3 0.3 2.7 2 1 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 CEH14571.1 - 3.4e-06 27.0 0.0 1.6e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Ten1_2 PF15490.1 CEH14572.1 - 2e-14 53.1 0.0 2.7e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit MFS_1 PF07690.11 CEH14573.1 - 3.9e-44 150.8 28.1 1.1e-43 149.3 17.7 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH14573.1 - 1.2e-09 37.2 2.1 1.2e-09 37.2 1.4 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter BT1 PF03092.11 CEH14573.1 - 0.00024 19.9 0.2 0.11 11.2 0.0 2.4 2 0 0 2 2 2 2 BT1 family TMEM141 PF15110.1 CEH14573.1 - 0.11 12.7 0.1 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 TMEM141 protein family DUF1295 PF06966.7 CEH14574.1 - 5.6e-05 22.5 0.0 8.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CEH14574.1 - 0.00066 19.8 0.6 0.0013 18.9 0.1 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CEH14574.1 - 0.00071 19.6 0.7 0.0013 18.8 0.1 1.8 2 1 0 2 2 2 1 Phospholipid methyltransferase P12 PF12669.2 CEH14574.1 - 0.09 12.9 0.4 0.27 11.4 0.3 1.8 1 0 0 1 1 1 0 Virus attachment protein p12 family EmrE PF13536.1 CEH14574.1 - 9.5 6.4 8.6 28 4.9 2.9 3.1 2 1 0 2 2 2 0 Multidrug resistance efflux transporter CPSase_L_D2 PF02786.12 CEH14575.1 - 1.3e-68 230.4 0.0 2.3e-68 229.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CEH14575.1 - 6e-42 142.2 0.0 1.5e-41 140.8 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CEH14575.1 - 5.1e-36 122.9 0.0 1e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CEH14575.1 - 1.7e-15 56.4 2.3 3.4e-15 55.4 1.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CEH14575.1 - 7.3e-13 48.6 0.0 1.6e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CEH14575.1 - 3.3e-12 46.2 0.0 5.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 CEH14575.1 - 7.4e-12 44.6 0.0 1.9e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CEH14575.1 - 9.3e-08 31.6 0.4 4.2e-06 26.3 0.1 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp PF02222.17 CEH14575.1 - 1.8e-05 24.1 0.0 5.2e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CEH14575.1 - 0.00056 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CEH14575.1 - 0.0012 18.3 0.0 0.011 15.2 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 CEH14575.1 - 0.0019 18.4 0.6 3.6 7.9 0.1 3.0 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.14 CEH14575.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.4 CEH14575.1 - 0.052 13.2 0.3 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_2 PF12700.2 CEH14575.1 - 0.065 12.3 0.2 0.7 8.9 0.0 2.0 1 1 1 2 2 2 0 HlyD family secretion protein Abhydrolase_6 PF12697.2 CEH14577.1 - 1e-17 64.7 0.1 1.4e-17 64.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH14577.1 - 2.4e-11 43.5 0.0 3.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH14577.1 - 5.2e-08 32.7 0.1 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEH14577.1 - 0.042 13.0 0.0 0.45 9.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.8 CEH14577.1 - 0.08 12.3 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) PGAP1 PF07819.8 CEH14577.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein 2-Hacid_dh_C PF02826.14 CEH14578.1 - 2.4e-40 137.5 0.0 1.1e-28 99.5 0.0 2.2 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CEH14578.1 - 6.2e-27 93.6 0.0 7.7e-27 93.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 CEH14578.1 - 0.03 14.7 0.0 0.12 12.8 0.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Mito_carr PF00153.22 CEH14579.1 - 1.4e-49 165.7 1.6 1.7e-19 69.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.13 CEH14580.1 - 1.1e-07 31.5 9.9 1.9e-07 30.8 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 CEH14582.1 - 3.2e-58 197.3 0.0 7.2e-37 126.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 HSP70 PF00012.15 CEH14583.1 - 6.6e-263 873.0 11.4 7.6e-263 872.8 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEH14583.1 - 5.8e-19 67.8 0.7 2.9e-17 62.2 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Spectrin PF00435.16 CEH14583.1 - 0.013 15.7 8.9 0.49 10.7 0.4 3.0 3 0 0 3 3 3 0 Spectrin repeat Hydantoinase_A PF01968.13 CEH14583.1 - 0.022 13.8 0.4 0.022 13.8 0.3 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CEH14583.1 - 0.064 12.8 0.1 0.48 10.0 0.0 2.4 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain FUSC PF04632.7 CEH14583.1 - 0.19 10.1 1.0 0.3 9.4 0.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FtsA PF14450.1 CEH14583.1 - 0.84 9.4 3.8 78 3.1 2.6 3.7 1 1 0 1 1 1 0 Cell division protein FtsA Ribosomal_L2_C PF03947.13 CEH14584.1 - 3.5e-42 143.2 2.3 5.4e-42 142.6 1.6 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CEH14584.1 - 8.3e-16 57.7 0.0 1.8e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.11 CEH14585.1 - 2.8e-26 92.0 40.4 6e-25 87.6 23.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3963 PF13124.1 CEH14585.1 - 1.1 9.1 4.2 28 4.6 1.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) Band_7 PF01145.20 CEH14587.1 - 1.2e-25 90.5 0.4 1.6e-25 90.0 0.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Vps52 PF04129.7 CEH14588.1 - 4.9e-33 114.4 0.0 1.4e-29 102.9 0.0 2.3 2 0 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.4 CEH14588.1 - 8.8e-09 34.0 1.7 2.7e-08 32.4 1.0 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec3 DUF1319 PF07028.6 CEH14588.1 - 0.8 9.9 5.0 0.29 11.3 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Zn_clus PF00172.13 CEH14589.1 - 4e-10 39.4 22.9 5.6e-06 26.1 5.6 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PRMT5 PF05185.11 CEH14590.1 - 1.9e-148 495.0 0.0 2.5e-148 494.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Oxidored_FMN PF00724.15 CEH14590.1 - 2.3e-43 148.5 0.0 9e-40 136.6 0.0 2.2 1 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Methyltransf_18 PF12847.2 CEH14590.1 - 0.00022 21.7 0.0 0.00061 20.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH14590.1 - 0.0013 18.2 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Nuc_deoxyrib_tr PF05014.10 CEH14590.1 - 0.045 13.6 0.0 2 8.2 0.0 2.6 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase WD40 PF00400.27 CEH14591.1 - 5e-33 111.7 5.4 2.6e-06 27.1 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CEH14591.1 - 1.3e-06 28.3 1.8 0.00015 21.5 0.6 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DHC_N1 PF08385.7 CEH14594.1 - 1e-185 618.4 2.6 2.1e-184 614.1 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CEH14594.1 - 9.7e-114 380.0 0.1 3.7e-113 378.1 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CEH14594.1 - 6.6e-51 173.0 0.0 2.3e-50 171.3 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CEH14594.1 - 1.2e-31 109.2 0.0 3.9e-13 49.3 0.0 5.8 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 CEH14594.1 - 6.2e-24 84.4 0.0 1.1e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CEH14594.1 - 5.6e-22 78.1 0.0 9e-20 70.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA PF00004.24 CEH14594.1 - 6.8e-15 55.4 0.0 0.0017 18.5 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEH14594.1 - 1.4e-12 47.9 1.0 0.0075 16.4 0.0 6.1 5 1 1 6 6 5 3 AAA domain AAA_16 PF13191.1 CEH14594.1 - 1e-10 41.9 4.4 0.21 11.5 0.2 7.4 5 1 1 6 6 6 2 AAA ATPase domain AAA_19 PF13245.1 CEH14594.1 - 2.1e-10 40.2 0.2 0.22 11.2 0.0 4.8 4 0 0 4 4 4 3 Part of AAA domain AAA_17 PF13207.1 CEH14594.1 - 5.7e-09 36.8 0.0 0.67 10.7 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 CEH14594.1 - 5.3e-07 29.9 0.0 1.9 8.8 0.0 5.0 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 CEH14594.1 - 5.3e-07 28.8 0.0 0.014 14.3 0.0 3.5 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_33 PF13671.1 CEH14594.1 - 6e-06 26.1 0.2 0.93 9.3 0.0 4.7 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 CEH14594.1 - 5.5e-05 22.6 0.0 2.6 7.6 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 CEH14594.1 - 5.6e-05 22.6 0.0 0.063 12.6 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CEH14594.1 - 8.5e-05 21.8 0.4 0.63 9.1 0.0 3.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CEH14594.1 - 0.00079 19.7 0.6 8.2 6.7 0.0 4.5 4 0 0 4 4 3 0 ABC transporter AAA_14 PF13173.1 CEH14594.1 - 0.0011 18.8 0.0 0.26 11.1 0.0 3.9 4 0 0 4 4 3 1 AAA domain Sigma54_activ_2 PF14532.1 CEH14594.1 - 0.0074 16.3 0.0 9.6 6.2 0.0 4.1 5 0 0 5 5 3 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 CEH14594.1 - 0.013 14.5 0.0 0.45 9.5 0.0 3.4 4 0 0 4 4 4 0 Zeta toxin RNA_helicase PF00910.17 CEH14594.1 - 0.016 15.3 0.5 17 5.6 0.0 4.2 4 0 0 4 4 4 0 RNA helicase ResIII PF04851.10 CEH14594.1 - 0.028 14.2 0.0 4.3 7.1 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF258 PF03193.11 CEH14594.1 - 0.03 13.4 0.2 37 3.4 0.0 3.6 4 0 0 4 4 3 0 Protein of unknown function, DUF258 AAA_11 PF13086.1 CEH14594.1 - 0.089 12.3 4.3 1.7 8.1 0.0 4.2 5 0 0 5 5 5 0 AAA domain Sigma54_activat PF00158.21 CEH14594.1 - 0.12 11.8 0.0 15 5.0 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain RNase_P_p30 PF01876.11 CEH14596.1 - 8.8e-38 128.8 0.2 3.8e-37 126.8 0.0 1.9 2 0 0 2 2 2 1 RNase P subunit p30 LIM_bind PF01803.11 CEH14597.1 - 1.6e-34 119.0 0.0 5.8e-18 64.8 0.0 3.3 2 1 0 3 3 3 3 LIM-domain binding protein DUF3546 PF12066.3 CEH14598.1 - 8e-15 54.8 0.3 2.2e-14 53.3 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 CEH14598.1 - 2.4e-06 27.9 0.0 6.2e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DDE_3 PF13358.1 CEH14599.1 - 0.061 13.0 0.1 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 DDE superfamily endonuclease BSP_II PF05432.6 CEH14600.1 - 0.023 13.9 10.3 0.033 13.4 7.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF605 PF04652.11 CEH14600.1 - 0.046 13.1 6.1 0.074 12.4 4.2 1.3 1 0 0 1 1 1 0 Vta1 like TFIIF_alpha PF05793.7 CEH14600.1 - 0.055 11.8 12.9 0.073 11.4 8.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 CEH14600.1 - 0.1 11.0 7.5 0.14 10.5 5.2 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 CEH14600.1 - 0.68 8.5 23.5 1.2 7.8 16.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.5 CEH14600.1 - 1.8 7.5 18.2 2.4 7.1 12.6 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 CEH14600.1 - 4.8 4.9 22.1 6.4 4.5 15.3 1.0 1 0 0 1 1 1 0 Nop14-like family Nop52 PF05997.7 CEH14601.1 - 9e-63 211.5 0.0 1.1e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.1 CEH14601.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II PALP PF00291.20 CEH14602.1 - 1.2e-60 205.3 0.1 1.5e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_C48 PF02902.14 CEH14603.1 - 3.1e-28 98.8 0.0 8.2e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Arf PF00025.16 CEH14604.1 - 7.2e-64 214.2 0.0 8.3e-64 214.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CEH14604.1 - 1.7e-13 50.0 0.1 1e-07 31.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CEH14604.1 - 3e-09 36.4 0.0 3.8e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CEH14604.1 - 7.9e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CEH14604.1 - 1.8e-07 30.5 0.0 2.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CEH14604.1 - 4.6e-07 30.3 0.0 8.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CEH14604.1 - 5.6e-07 28.9 0.0 7.4e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CEH14604.1 - 0.00056 19.4 0.0 0.016 14.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_membrane PF00664.18 CEH14605.1 - 3.2e-58 197.3 23.4 3.6e-33 115.1 7.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEH14605.1 - 2.2e-43 147.8 3.6 4.5e-18 65.8 0.0 3.8 2 1 1 3 3 3 3 ABC transporter AAA_21 PF13304.1 CEH14605.1 - 1.4e-17 64.5 0.3 3.8e-05 23.8 0.0 4.3 3 1 1 4 4 4 4 AAA domain AAA_16 PF13191.1 CEH14605.1 - 1.3e-10 41.5 2.8 0.00035 20.6 0.3 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CEH14605.1 - 1.6e-10 40.6 6.0 0.0013 18.0 0.2 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CEH14605.1 - 4.1e-08 32.6 0.7 0.00075 18.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CEH14605.1 - 8.6e-07 29.4 0.2 0.054 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CEH14605.1 - 8.8e-07 29.7 1.0 0.026 15.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 CEH14605.1 - 1.7e-06 27.5 1.7 0.015 14.7 0.1 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CEH14605.1 - 2.8e-06 27.2 0.1 0.0064 16.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 CEH14605.1 - 8.4e-06 26.1 1.0 0.14 12.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CEH14605.1 - 2.1e-05 24.6 2.6 0.022 14.8 0.2 3.2 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 CEH14605.1 - 2.3e-05 24.8 0.0 0.19 12.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 CEH14605.1 - 8e-05 21.6 0.3 0.07 12.0 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Arch_ATPase PF01637.13 CEH14605.1 - 8.5e-05 22.3 0.1 0.048 13.3 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 CEH14605.1 - 9.9e-05 21.5 0.7 0.15 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 CEH14605.1 - 0.00022 20.9 0.4 0.26 10.9 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 CEH14605.1 - 0.00023 20.7 0.8 0.037 13.4 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_33 PF13671.1 CEH14605.1 - 0.00034 20.5 1.7 5.4 6.8 0.1 3.7 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 CEH14605.1 - 0.00099 18.2 0.2 0.79 8.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin TrwB_AAD_bind PF10412.4 CEH14605.1 - 0.0011 17.6 0.9 0.71 8.4 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 CEH14605.1 - 0.003 17.2 1.8 1.5 8.4 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.1 CEH14605.1 - 0.004 16.7 3.0 0.94 9.0 0.3 2.5 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 CEH14605.1 - 0.0043 16.7 0.5 0.059 13.0 0.1 2.3 2 0 0 2 2 2 1 NTPase Dynamin_N PF00350.18 CEH14605.1 - 0.0045 16.8 4.6 1.3 8.8 0.1 2.9 2 1 0 3 3 3 2 Dynamin family AAA PF00004.24 CEH14605.1 - 0.0048 17.1 0.5 2.2 8.4 0.1 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 CEH14605.1 - 0.022 13.5 0.7 0.61 8.8 0.1 2.3 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 CEH14605.1 - 0.023 14.1 3.0 1.9 7.8 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 CEH14605.1 - 0.025 14.3 3.2 0.038 13.8 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 CEH14605.1 - 0.029 13.8 3.2 1.4 8.3 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 CEH14605.1 - 0.029 13.4 0.1 22 3.9 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain ATP-synt_ab PF00006.20 CEH14605.1 - 0.036 13.5 0.0 6.5 6.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 CEH14605.1 - 0.042 13.3 0.4 7.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 CEH14605.1 - 0.047 13.8 0.2 14 5.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 CEH14605.1 - 0.058 13.3 0.1 7.8 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CEH14605.1 - 0.09 12.7 0.3 8.7 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CEH14605.1 - 0.14 10.9 1.5 1.6 7.4 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 CEH14605.1 - 0.18 11.4 1.9 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 CEH14605.1 - 0.22 11.2 3.7 21 4.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 CEH14605.1 - 0.29 9.7 0.1 4.8 5.7 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain ACT_3 PF10000.4 CEH14606.1 - 3.3e-08 33.1 0.3 3.4e-07 29.8 0.2 2.3 2 1 0 2 2 2 1 ACT domain ACT_7 PF13840.1 CEH14606.1 - 0.012 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 ACT domain adh_short PF00106.20 CEH14607.1 - 2.8e-26 92.3 0.0 4.3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH14607.1 - 1e-19 71.2 0.0 1.3e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH14607.1 - 1.5e-12 47.5 0.1 2.4e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CEH14607.1 - 0.002 18.1 0.1 0.49 10.3 0.0 2.4 1 1 1 2 2 2 2 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CEH14607.1 - 0.0056 16.4 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CEH14607.1 - 0.015 14.7 0.1 0.099 12.0 0.0 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Fe-ADH PF00465.14 CEH14608.1 - 5.7e-62 209.4 0.1 2e-61 207.6 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CEH14608.1 - 1.1e-12 47.8 0.1 2.2e-05 23.9 0.0 2.7 2 1 0 2 2 2 2 Iron-containing alcohol dehydrogenase RabGAP-TBC PF00566.13 CEH14609.1 - 1.7e-50 171.4 0.0 3.8e-50 170.3 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ras PF00071.17 CEH14610.1 - 2e-57 193.1 0.1 2.3e-57 192.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH14610.1 - 2.9e-19 69.6 0.0 4.3e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH14610.1 - 8.9e-09 34.8 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEH14610.1 - 2.6e-06 26.9 0.0 4.4e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CEH14610.1 - 0.013 14.8 0.0 0.024 13.8 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 CEH14610.1 - 0.019 14.8 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CEH14610.1 - 0.056 12.5 0.0 0.066 12.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Abhydrolase_2 PF02230.11 CEH14611.1 - 2.8e-06 26.9 0.0 4.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CEH14611.1 - 0.0016 18.2 0.0 0.0053 16.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 CEH14611.1 - 0.0052 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Cutinase Abhydrolase_3 PF07859.8 CEH14611.1 - 0.0088 15.6 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 CEH14611.1 - 0.0095 15.4 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2235 PF09994.4 CEH14611.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_6 PF12697.2 CEH14611.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DnaB PF00772.16 CEH14611.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Aminotran_5 PF00266.14 CEH14612.1 - 3.2e-17 62.3 0.0 6.1e-17 61.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V SNARE_assoc PF09335.6 CEH14615.1 - 7.4e-07 29.4 3.3 7.4e-07 29.4 2.3 2.6 2 0 0 2 2 2 1 SNARE associated Golgi protein Sgf11 PF08209.6 CEH14616.1 - 4.2e-10 38.7 0.4 4.2e-10 38.7 0.3 1.6 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 CEH14616.1 - 0.0024 17.4 0.4 0.011 15.3 0.1 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Yippee-Mis18 PF03226.9 CEH14618.1 - 3.5e-19 68.6 0.3 4e-19 68.4 0.2 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Endonuclease_7 PF02945.10 CEH14618.1 - 0.0075 15.9 1.3 0.018 14.6 0.9 1.7 1 1 0 1 1 1 1 Recombination endonuclease VII Phyto_Pns9_10 PF05878.6 CEH14618.1 - 0.0084 15.1 0.0 0.0098 14.9 0.0 1.1 1 0 0 1 1 1 1 Phytoreovirus nonstructural protein Pns9/Pns10 HNH_5 PF14279.1 CEH14618.1 - 0.088 12.8 0.5 1.3 9.1 0.3 2.2 1 1 0 1 1 1 0 HNH endonuclease DZR PF12773.2 CEH14618.1 - 0.11 12.3 0.2 4.5 7.1 0.0 2.4 2 1 0 2 2 2 0 Double zinc ribbon GYF PF02213.11 CEH14619.1 - 3e-15 55.5 0.0 5.5e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 GYF domain DUF4339 PF14237.1 CEH14619.1 - 0.017 14.6 0.2 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) DUF3292 PF11696.3 CEH14620.1 - 6.7e-150 500.0 4.9 1.8e-122 409.4 0.0 3.5 1 1 2 3 3 3 3 Protein of unknown function (DUF3292) Hexapep PF00132.19 CEH14621.1 - 9e-12 43.9 3.2 1.4e-11 43.3 2.2 1.3 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CEH14621.1 - 1.2e-10 40.6 1.7 1.9e-10 40.0 1.2 1.3 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 CEH14621.1 - 5e-09 36.0 0.1 9.6e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 Maltose acetyltransferase HEAT_2 PF13646.1 CEH14622.1 - 6.6e-32 109.6 7.2 3.8e-18 65.5 0.7 3.3 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 CEH14622.1 - 2.3e-17 61.6 7.2 7e-06 26.0 0.0 6.7 6 1 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 CEH14622.1 - 5.1e-07 29.9 13.8 0.077 13.5 0.0 5.9 3 3 3 6 6 6 4 HEAT-like repeat HEAT PF02985.17 CEH14622.1 - 5.7e-07 29.0 8.0 0.024 14.6 0.0 6.3 6 1 1 7 7 7 2 HEAT repeat Arm PF00514.18 CEH14622.1 - 0.0007 19.3 0.6 1.6 8.6 0.1 3.7 2 1 1 3 3 3 2 Armadillo/beta-catenin-like repeat Vitellogenin_N PF01347.17 CEH14622.1 - 0.0077 14.5 0.1 0.13 10.4 0.0 2.3 1 1 1 2 2 2 1 Lipoprotein amino terminal region DUF2150 PF09920.4 CEH14622.1 - 0.021 14.4 0.2 5.7 6.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) UPF0147 PF03685.8 CEH14622.1 - 0.13 12.1 0.2 3.1 7.7 0.0 3.1 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0147) DnaJ-X PF14308.1 CEH14622.1 - 0.35 10.1 3.0 5.9 6.0 0.1 2.9 3 0 0 3 3 3 0 X-domain of DnaJ-containing RNA_pol_Rpc4 PF05132.9 CEH14623.1 - 1.7e-26 92.7 9.6 8.4e-26 90.4 0.0 3.4 3 0 0 3 3 3 2 RNA polymerase III RPC4 TGS PF02824.16 CEH14626.1 - 3.5e-20 71.5 0.1 1.2e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 CEH14626.1 - 2.5e-18 66.1 0.0 5.4e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEH14626.1 - 3.7e-12 45.8 0.0 6.9e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CEH14626.1 - 0.00026 20.8 0.2 0.046 13.5 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 CEH14626.1 - 0.0009 19.7 0.0 0.0023 18.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MCM PF00493.18 CEH14626.1 - 0.03 13.1 0.0 0.058 12.1 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family ABC_tran PF00005.22 CEH14626.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 CEH14626.1 - 0.047 13.6 0.2 0.09 12.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CEH14626.1 - 0.096 12.9 2.3 11 6.3 0.1 2.4 1 1 0 2 2 2 0 AAA domain Aa_trans PF01490.13 CEH14627.1 - 3e-86 289.4 0.4 4.5e-86 288.9 0.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CEH14627.1 - 8.2e-05 21.5 14.2 8.2e-05 21.5 9.9 1.8 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family CS PF04969.11 CEH14628.1 - 2.8e-06 27.7 0.1 5.1e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 CS domain Med15 PF09606.5 CEH14628.1 - 0.0012 17.1 0.9 0.0016 16.7 0.6 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal tRNA-synt_1g PF09334.6 CEH14628.1 - 0.0062 15.2 0.4 0.0081 14.8 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) CRAL_TRIO PF00650.15 CEH14629.1 - 3.7e-34 117.5 0.0 5.9e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEH14629.1 - 5.1e-10 39.3 0.3 1.5e-09 37.7 0.2 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ThiS PF02597.15 CEH14629.1 - 0.00037 20.8 0.0 0.0038 17.6 0.0 2.6 1 1 0 1 1 1 1 ThiS family DUF2422 PF10337.4 CEH14629.1 - 0.45 9.2 1.5 0.74 8.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Metallophos PF00149.23 CEH14630.1 - 4.5e-07 29.4 0.9 7.7e-07 28.7 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Defensin_1 PF00323.14 CEH14631.1 - 0.2 12.0 6.9 2.3 8.6 0.5 3.0 2 0 0 2 2 2 0 Mammalian defensin CP12 PF02672.10 CEH14631.1 - 0.88 10.0 9.7 2.6 8.5 0.0 4.4 4 0 0 4 4 4 0 CP12 domain Cytidylate_kin PF02224.13 CEH14632.1 - 0.44 9.9 5.9 0.54 9.6 4.1 1.1 1 0 0 1 1 1 0 Cytidylate kinase Viral_P18 PF04521.8 CEH14632.1 - 0.66 9.4 4.4 0.79 9.1 3.1 1.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein RVT_1 PF00078.22 CEH14634.1 - 1.1e-20 73.9 0.0 2.8e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEH14634.1 - 6e-19 68.3 0.0 1.3e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Gti1_Pac2 PF09729.4 CEH14635.1 - 2.7e-41 141.2 0.1 7e-31 107.3 0.0 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family DUF3712 PF12505.3 CEH14637.1 - 4.4e-17 62.2 0.0 7.1e-09 35.7 0.0 5.2 5 1 0 5 5 5 3 Protein of unknown function (DUF3712) LEA_2 PF03168.8 CEH14637.1 - 2.3e-06 27.9 0.1 0.035 14.4 0.0 5.0 5 0 0 5 5 5 2 Late embryogenesis abundant protein 60KD_IMP PF02096.15 CEH14638.1 - 6.9e-06 25.8 0.0 8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Sensor PF13796.1 CEH14638.1 - 0.0025 17.4 0.5 0.0032 17.1 0.4 1.1 1 0 0 1 1 1 1 Putative sensor Gln-synt_C PF00120.19 CEH14643.1 - 1.5e-60 204.4 0.0 1.9e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CEH14643.1 - 7.1e-19 67.1 0.0 1.1e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain FAD_binding_2 PF00890.19 CEH14643.1 - 0.003 16.4 0.0 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2985 PF11204.3 CEH14644.1 - 2.7e-31 107.1 4.8 4.5e-31 106.4 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) WES_acyltransf PF03007.11 CEH14645.1 - 5e-16 59.0 0.0 1.2e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.8 CEH14645.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) SLAC1 PF03595.12 CEH14646.1 - 2.1e-69 233.6 46.7 2.4e-69 233.5 32.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ABC1 PF03109.11 CEH14647.1 - 2.8e-25 88.6 0.0 5.5e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family PI3_PI4_kinase PF00454.22 CEH14647.1 - 0.011 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase ESSS PF10183.4 CEH14649.1 - 0.15 12.4 1.4 0.33 11.3 0.1 2.1 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4611 PF15387.1 CEH14649.1 - 0.5 10.5 5.8 0.065 13.3 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MIS13 PF08202.6 CEH14650.1 - 3.3e-15 55.9 6.0 2.1e-14 53.3 2.7 3.1 2 1 0 2 2 2 1 Mis12-Mtw1 protein family WD40 PF00400.27 CEH14651.1 - 1.4e-17 62.7 16.3 0.00092 19.0 0.0 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat SRA1 PF07304.6 CEH14651.1 - 3.7e-05 23.4 0.0 0.0001 22.0 0.0 1.7 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 CEH14651.1 - 0.059 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 pRN1_helical PF13010.1 CEH14652.1 - 1 9.0 0.0 1.8 8.2 0.0 1.3 1 0 0 1 1 1 0 Primase helical domain Prp19_bind PF06991.6 CEH14653.1 - 1.9e-37 129.0 28.5 1.9e-37 129.0 19.8 4.8 3 1 0 3 3 3 2 Splicing factor, Prp19-binding domain zf-CCHC PF00098.18 CEH14653.1 - 0.83 9.6 4.3 3 7.9 3.0 1.9 1 1 0 1 1 1 0 Zinc knuckle tRNA-synt_1 PF00133.17 CEH14654.1 - 2.9e-38 131.2 0.0 4.2e-30 104.3 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CEH14654.1 - 2.8e-17 62.4 0.0 3.6e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CEH14654.1 - 1.4e-11 44.3 0.4 2.9e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CEH14654.1 - 3.2e-07 29.7 0.0 6.8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Cys_Met_Meta_PP PF01053.15 CEH14655.1 - 1.6e-120 401.9 0.0 2.4e-120 401.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 CEH14655.1 - 2.4e-15 56.3 2.9 2.4e-15 56.3 2.0 3.3 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CEH14655.1 - 4.6e-07 29.9 0.1 1.5e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 CEH14655.1 - 0.011 14.9 0.3 0.023 13.9 0.2 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Lyase_aromatic PF00221.14 CEH14657.1 - 0.091 11.1 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Aromatic amino acid lyase RPA_interact_C PF14768.1 CEH14658.1 - 0.036 14.4 0.1 0.097 13.0 0.0 1.7 2 0 0 2 2 2 0 Replication protein A interacting C-terminal Pyr_redox_2 PF07992.9 CEH14659.1 - 3.2e-42 144.6 0.0 6.4e-42 143.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CEH14659.1 - 6.2e-33 113.1 0.9 6.2e-33 113.1 0.6 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CEH14659.1 - 3.1e-22 78.7 9.3 2.2e-18 66.4 1.2 3.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEH14659.1 - 1.4e-15 57.9 0.1 9.1e-09 35.6 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEH14659.1 - 4e-06 25.5 4.5 0.071 11.5 0.8 3.5 3 1 1 4 4 4 2 HI0933-like protein FAD_oxidored PF12831.2 CEH14659.1 - 7e-06 25.3 0.4 2e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 CEH14659.1 - 0.0012 17.8 0.1 0.0047 15.8 0.0 1.8 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 CEH14659.1 - 0.002 18.3 0.7 0.14 12.3 0.3 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 CEH14659.1 - 0.0036 17.3 3.1 0.012 15.6 1.8 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CEH14659.1 - 0.0047 15.8 7.5 0.067 12.0 2.4 3.1 3 0 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.13 CEH14659.1 - 0.0078 15.8 3.8 0.041 13.5 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 CEH14659.1 - 0.0097 15.0 0.2 0.02 14.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CEH14659.1 - 0.28 10.0 5.3 0.1 11.4 0.4 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 CEH14659.1 - 0.99 8.1 5.6 2.4 6.9 2.5 2.4 2 1 0 2 2 2 0 Glucose inhibited division protein A SMK-1 PF04802.10 CEH14661.1 - 4.2e-63 212.3 0.0 1.2e-62 210.9 0.0 1.8 2 1 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Pribosyltran PF00156.22 CEH14663.1 - 1.4e-15 57.1 0.5 2.8e-15 56.1 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Fels1 PF05666.6 CEH14663.1 - 0.019 14.3 0.1 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Fels-1 Prophage Protein-like NDK PF00334.14 CEH14664.1 - 4e-32 110.8 0.0 6e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glycos_transf_4 PF00953.16 CEH14665.1 - 3.7e-31 108.0 6.2 1e-30 106.6 4.3 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 4 Mito_carr PF00153.22 CEH14667.1 - 3.8e-72 238.0 1.7 4.6e-24 83.9 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein HAMP PF00672.20 CEH14667.1 - 0.2 11.8 2.4 17 5.6 0.1 2.9 3 0 0 3 3 3 0 HAMP domain ABC_membrane_2 PF06472.10 CEH14668.1 - 9.6e-98 326.7 1.2 1.2e-97 326.3 0.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CEH14668.1 - 3.7e-18 66.1 0.0 6.9e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 CEH14668.1 - 0.0027 18.0 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 CEH14668.1 - 0.0079 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEH14668.1 - 0.0085 16.0 0.0 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 CEH14668.1 - 0.019 14.2 0.1 0.17 11.0 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF2990 PF11693.3 CEH14668.1 - 0.029 14.2 0.1 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) AAA_29 PF13555.1 CEH14668.1 - 0.029 13.8 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CEH14668.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase HA2 PF04408.18 CEH14669.1 - 2.1e-15 56.6 1.5 9.1e-15 54.5 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CEH14669.1 - 3.4e-12 46.0 0.4 2.8e-11 43.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEH14669.1 - 4.5e-07 29.5 0.4 1e-06 28.3 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 CEH14669.1 - 1.8e-05 25.2 9.0 0.0057 17.1 0.0 3.3 3 0 0 3 3 3 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.11 CEH14669.1 - 5.8e-05 22.9 0.2 0.00023 20.9 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.10 CEH14669.1 - 0.032 14.0 0.3 1.6 8.5 0.2 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 CEH14670.1 - 2.9e-50 169.8 0.0 3.1e-41 140.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEH14670.1 - 5.2e-06 26.5 0.0 5.2e-06 26.5 0.0 4.6 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 CEH14670.1 - 7e-05 22.9 0.4 0.0064 16.6 0.0 3.7 3 1 0 3 3 2 1 AAA domain AAA_2 PF07724.9 CEH14670.1 - 8.3e-05 22.5 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 CEH14670.1 - 0.00015 21.2 0.0 0.00063 19.2 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 CEH14670.1 - 0.0012 18.6 0.0 0.0086 15.8 0.0 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CEH14670.1 - 0.002 17.5 0.0 0.013 14.8 0.0 2.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEH14670.1 - 0.0028 17.5 2.5 0.033 14.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 CEH14670.1 - 0.0033 18.2 0.7 0.026 15.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CEH14670.1 - 0.0074 16.0 0.0 0.0074 16.0 0.0 2.9 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 CEH14670.1 - 0.0079 16.5 0.0 0.059 13.6 0.0 2.5 3 0 0 3 3 2 1 AAA domain PhoH PF02562.11 CEH14670.1 - 0.019 14.2 0.3 0.47 9.6 0.0 2.6 3 0 0 3 3 3 0 PhoH-like protein AAA_11 PF13086.1 CEH14670.1 - 0.02 14.4 0.1 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CEH14670.1 - 0.028 14.4 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 CEH14670.1 - 0.076 12.1 1.2 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CEH14670.1 - 0.078 12.4 0.0 0.76 9.2 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 CEH14670.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 CEH14670.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Bromodomain PF00439.20 CEH14670.1 - 0.26 11.2 0.0 0.58 10.1 0.0 1.5 1 0 0 1 1 1 0 Bromodomain Torsin PF06309.6 CEH14670.1 - 0.51 10.2 0.0 1.1 9.0 0.0 1.5 1 0 0 1 1 1 0 Torsin Velvet PF11754.3 CEH14671.1 - 3e-62 209.8 0.0 5.1e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Hydrolase_like PF13242.1 CEH14672.1 - 6.3e-19 67.4 0.1 5.4e-18 64.4 0.0 2.5 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CEH14672.1 - 1.9e-16 59.7 0.0 4.8e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEH14672.1 - 3.3e-06 27.4 0.0 0.00062 20.0 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CEH14672.1 - 0.00051 20.5 0.0 0.62 10.4 0.0 2.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Mito_carr PF00153.22 CEH14673.1 - 8.1e-32 108.7 6.1 2.7e-13 49.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LEA_4 PF02987.11 CEH14673.1 - 0.021 14.6 0.4 0.04 13.7 0.3 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein MFS_1 PF07690.11 CEH14674.1 - 2.5e-40 138.2 54.2 5.3e-32 110.8 13.0 3.9 2 2 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 CEH14674.1 - 2.1e-15 55.9 20.3 3.1e-15 55.4 14.1 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CEH14674.1 - 9e-11 40.9 5.9 9e-11 40.9 4.1 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter MSA-2c PF12238.3 CEH14674.1 - 0.086 12.5 5.9 0.18 11.4 4.1 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c PALP PF00291.20 CEH14676.1 - 3.4e-26 92.2 0.0 6.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 CEH14676.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain FDF PF09532.5 CEH14677.1 - 3.9e-08 33.7 0.4 3.9e-08 33.7 0.3 2.1 2 0 0 2 2 2 1 FDF domain Ribophorin_I PF04597.9 CEH14678.1 - 4.5e-98 328.5 0.0 5.7e-98 328.2 0.0 1.1 1 0 0 1 1 1 1 Ribophorin I Yos1 PF08571.5 CEH14680.1 - 1.7e-29 101.7 0.6 2e-29 101.5 0.4 1.0 1 0 0 1 1 1 1 Yos1-like Phosducin PF02114.11 CEH14681.1 - 8e-10 37.8 0.5 2.6e-09 36.2 0.0 2.0 2 1 1 3 3 3 1 Phosducin Nucleoplasmin PF03066.10 CEH14681.1 - 0.95 8.9 5.6 2 7.8 0.9 2.3 2 0 0 2 2 2 0 Nucleoplasmin tRNA-synt_1c PF00749.16 CEH14682.1 - 7.3e-103 343.5 0.0 9.7e-103 343.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CEH14682.1 - 1.7e-29 102.6 0.0 2.8e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CEH14682.1 - 0.011 16.1 0.0 0.035 14.5 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 CEH14682.1 - 0.022 13.8 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain AMP-binding PF00501.23 CEH14683.1 - 1.1e-62 211.8 0.1 3.2e-62 210.2 0.1 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEH14683.1 - 0.0023 18.8 0.0 0.0062 17.4 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Antimicrobial15 PF08110.7 CEH14685.1 - 0.093 12.7 0.2 0.22 11.5 0.2 1.6 1 0 0 1 1 1 0 Ocellatin family Fungal_trans PF04082.13 CEH14686.1 - 1.4e-10 40.4 0.1 2.4e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH14686.1 - 1.9e-06 27.6 10.4 4.2e-06 26.5 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 CEH14686.1 - 1.4 9.1 11.0 0.49 10.6 5.4 1.8 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region EB1 PF03271.12 CEH14688.1 - 1.2e-15 57.2 0.4 2.1e-15 56.4 0.2 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 CEH14688.1 - 1e-06 28.7 0.2 1.5e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Kdo PF06293.9 CEH14689.1 - 0.0036 16.3 0.1 0.009 15.0 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CEH14689.1 - 0.09 11.9 0.3 0.22 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain Myosin_tail_1 PF01576.14 CEH14690.1 - 0.018 12.7 3.9 0.024 12.4 2.7 1.1 1 0 0 1 1 1 0 Myosin tail DUF2823 PF11034.3 CEH14691.1 - 4.2e-26 90.8 8.3 4.7e-26 90.6 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) DUF3005 PF11448.3 CEH14691.1 - 0.13 11.9 1.4 0.14 11.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3005) Peptidase_M24 PF00557.19 CEH14692.1 - 1.1e-20 74.1 0.2 1.4e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 HTH_13 PF11972.3 CEH14692.1 - 0.07 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain Di19_C PF14571.1 CEH14692.1 - 0.18 12.1 0.6 0.28 11.5 0.4 1.3 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal MRP-S25 PF13741.1 CEH14693.1 - 4.9e-35 121.0 0.0 9.5e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 SAICAR_synt PF01259.13 CEH14693.1 - 0.049 12.7 0.2 0.069 12.2 0.1 1.1 1 0 0 1 1 1 0 SAICAR synthetase Maf PF02545.9 CEH14694.1 - 4.8e-46 156.3 0.0 6e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Ndufs5 PF10200.4 CEH14695.1 - 5.4e-05 23.1 0.5 8.3e-05 22.5 0.3 1.4 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 CEH14695.1 - 0.0027 17.7 2.5 0.0027 17.7 1.7 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3128) Pet191_N PF10203.4 CEH14695.1 - 0.029 14.4 1.1 0.071 13.1 0.8 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CEH14695.1 - 0.06 13.1 0.7 0.094 12.4 0.5 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 CEH14695.1 - 0.15 12.0 0.3 0.15 12.0 0.2 2.5 2 1 1 3 3 3 0 Cytochrome oxidase c subunit VIb zf-HC5HC2H_2 PF13832.1 CEH14696.1 - 1.5e-33 115.0 9.8 1.5e-33 115.0 6.8 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CEH14696.1 - 9.8e-25 86.5 7.6 9.8e-25 86.5 5.2 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 CEH14696.1 - 1.3e-22 80.7 0.6 1.3e-22 80.7 0.4 3.8 3 1 0 3 3 3 1 Enhancer of polycomb-like Bromodomain PF00439.20 CEH14696.1 - 5.2e-19 67.9 0.0 9.8e-19 67.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 CEH14696.1 - 1.1e-14 53.4 2.6 1.1e-14 53.4 1.8 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 CEH14696.1 - 2.5e-09 36.6 25.0 8e-09 35.0 6.5 2.7 2 0 0 2 2 2 2 PHD-finger PWWP PF00855.12 CEH14696.1 - 0.00087 19.4 0.0 0.00087 19.4 0.0 2.7 2 1 0 2 2 2 1 PWWP domain C1_1 PF00130.17 CEH14696.1 - 9.3 6.0 17.8 0.08 12.6 1.2 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_transf_8 PF01501.15 CEH14697.1 - 1.5e-19 70.3 0.0 3.5e-19 69.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CEH14697.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative DUF1638 PF07796.6 CEH14698.1 - 0.066 12.8 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) DPBB_1 PF03330.13 CEH14698.1 - 0.088 12.8 0.2 0.17 11.9 0.1 1.6 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel CDC45 PF02724.9 CEH14700.1 - 1.2 7.0 5.4 2.4 6.0 3.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Mucin PF01456.12 CEH14701.1 - 0.0039 16.9 14.4 0.0049 16.6 10.0 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein SpoIIIAH PF12685.2 CEH14701.1 - 0.013 15.0 1.2 0.016 14.7 0.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1183 PF06682.7 CEH14701.1 - 0.054 13.0 4.6 0.065 12.8 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF3357 PF11837.3 CEH14701.1 - 0.08 12.7 1.8 0.15 11.9 1.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF2763 PF10961.3 CEH14701.1 - 2.8 8.3 5.7 0.31 11.4 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) WD40 PF00400.27 CEH14702.1 - 3.9e-73 238.9 33.3 1.4e-12 46.9 0.0 9.3 9 0 0 9 9 9 9 WD domain, G-beta repeat Nup160 PF11715.3 CEH14702.1 - 6.6e-09 34.4 7.4 0.00061 18.0 0.2 4.4 2 1 1 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 CEH14702.1 - 9.1e-05 22.2 0.0 0.0012 18.5 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CEH14702.1 - 0.034 13.2 0.5 5.9 5.8 0.0 2.7 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal NLE PF08154.7 CEH14702.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain Nucleoporin_N PF08801.6 CEH14702.1 - 0.14 10.8 7.9 0.98 8.0 0.2 3.8 2 2 1 3 3 3 0 Nup133 N terminal like IKI3 PF04762.7 CEH14702.1 - 0.15 9.8 0.1 0.38 8.5 0.1 1.6 1 0 0 1 1 1 0 IKI3 family ABC2_membrane PF01061.19 CEH14703.1 - 9.8e-39 132.6 19.3 1.2e-38 132.3 13.4 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CEH14703.1 - 1.1e-25 90.4 0.2 2.5e-25 89.3 0.0 1.6 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 CEH14703.1 - 1.1e-05 25.5 0.6 0.00048 20.1 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEH14703.1 - 0.00017 21.6 0.1 0.00046 20.2 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CEH14703.1 - 0.0003 20.2 0.0 0.0012 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CEH14703.1 - 0.00059 19.0 0.0 0.00087 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CEH14703.1 - 0.002 18.9 0.0 0.0038 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEH14703.1 - 0.0022 18.1 0.1 0.03 14.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CEH14703.1 - 0.0041 17.4 0.0 0.0079 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CEH14703.1 - 0.0047 16.8 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CEH14703.1 - 0.006 16.0 0.2 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 CEH14703.1 - 0.012 15.2 0.6 0.031 14.0 0.1 1.9 2 0 0 2 2 1 0 Part of AAA domain DUF87 PF01935.12 CEH14703.1 - 0.018 14.9 0.3 0.035 13.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 CEH14703.1 - 0.021 14.7 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CEH14703.1 - 0.022 14.2 0.1 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 CEH14703.1 - 0.037 12.9 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_15 PF13175.1 CEH14703.1 - 0.041 12.9 0.0 3.8 6.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 CEH14703.1 - 0.048 12.4 1.9 0.11 11.2 0.1 2.0 2 0 0 2 2 2 0 ArgK protein NACHT PF05729.7 CEH14703.1 - 0.053 13.1 0.1 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 CEH14703.1 - 0.07 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 CEH14703.1 - 0.091 12.4 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase FeoB_N PF02421.13 CEH14703.1 - 0.091 12.0 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.1 CEH14703.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CEH14703.1 - 0.2 11.9 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain EspB PF05802.6 CEH14703.1 - 0.57 9.0 5.0 0.53 9.1 1.3 2.0 2 0 0 2 2 2 0 Enterobacterial EspB protein Zn_clus PF00172.13 CEH14704.1 - 4.2e-07 29.7 8.9 8.5e-07 28.7 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CEH14704.1 - 0.04 12.7 0.0 0.075 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3294 PF07957.6 CEH14704.1 - 0.067 12.7 1.2 0.13 11.7 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Lipase_3 PF01764.20 CEH14705.1 - 8.5e-16 57.8 0.0 2.7e-15 56.2 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) tRNA-synt_2 PF00152.15 CEH14707.1 - 2.4e-83 279.6 0.0 4.1e-83 278.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CEH14707.1 - 4.4e-06 26.4 0.0 7.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CEH14707.1 - 0.048 12.8 0.1 5.9 6.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) RVT_1 PF00078.22 CEH14709.1 - 3.2e-16 59.3 0.0 5.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEH14711.1 - 5.4e-15 55.5 0.0 8.6e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEH14712.1 - 4e-08 32.8 0.4 1.5e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CEH14713.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CEH14714.1 - 0.0046 17.0 0.0 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein tRNA-synt_His PF13393.1 CEH14716.1 - 1e-35 123.2 9.6 9.3e-34 116.8 0.0 3.2 4 0 0 4 4 4 2 Histidyl-tRNA synthetase ERCC4 PF02732.10 CEH14716.1 - 2.1e-27 95.6 0.1 4.8e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain tRNA-synt_2b PF00587.20 CEH14716.1 - 1.5e-15 57.2 0.0 2.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.15 CEH14716.1 - 2.8e-10 39.7 3.2 1.1e-09 37.8 2.2 2.0 1 0 0 1 1 1 1 WHEP-TRS domain HGTP_anticodon PF03129.15 CEH14716.1 - 1.6e-06 27.9 0.0 4.8e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CEH14716.1 - 0.00021 20.1 0.2 0.011 14.5 0.1 2.6 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Complex1_30kDa PF00329.14 CEH14718.1 - 3.8e-36 123.4 0.1 5.6e-36 122.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Rifin_STEVOR PF02009.11 CEH14719.1 - 0.029 14.0 1.8 0.036 13.7 1.2 1.1 1 0 0 1 1 1 0 Rifin/stevor family HutD PF05962.6 CEH14719.1 - 0.03 14.0 0.2 0.039 13.6 0.2 1.1 1 0 0 1 1 1 0 HutD DUF1501 PF07394.7 CEH14719.1 - 0.033 13.0 4.2 0.041 12.7 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) MRP-S27 PF10037.4 CEH14719.1 - 0.12 11.2 3.1 0.14 11.0 2.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 TP53IP5 PF15331.1 CEH14719.1 - 0.24 11.2 5.8 0.32 10.8 4.1 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Dsh_C PF12316.3 CEH14719.1 - 0.3 11.1 6.6 0.36 10.9 4.6 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal HAUS6_N PF14661.1 CEH14719.1 - 0.41 9.9 8.1 0.5 9.6 5.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4407 PF14362.1 CEH14719.1 - 0.75 8.6 8.5 0.89 8.4 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 CEH14719.1 - 1.6 7.6 6.3 1.8 7.5 4.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 CEH14719.1 - 3.3 4.9 15.0 4 4.6 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4200 PF13863.1 CEH14719.1 - 4.1 7.3 15.2 7 6.6 10.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) HlyD PF00529.15 CEH14719.1 - 4.8 6.4 16.4 6 6.0 11.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF4337 PF14235.1 CEH14719.1 - 9.5 6.0 13.3 13 5.5 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2185 PF09951.4 CEH14720.1 - 2.9e-13 49.4 0.0 3.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2185) Barwin PF00967.12 CEH14720.1 - 0.064 12.9 0.1 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Barwin family ketoacyl-synt PF00109.21 CEH14722.1 - 2.6e-57 194.2 0.8 5.7e-57 193.0 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 CEH14722.1 - 2.3e-26 92.1 0.1 3.7e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Ketoacyl-synt_C PF02801.17 CEH14722.1 - 3.6e-15 55.8 5.7 2.4e-14 53.1 0.8 3.7 3 1 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 CEH14722.1 - 3.6e-05 23.9 0.0 9.6e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 CEH14722.1 - 0.62 9.7 5.9 0.52 10.0 0.6 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abhydrolase_6 PF12697.2 CEH14723.1 - 4.1e-24 85.7 0.1 8.3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family ADH_zinc_N PF00107.21 CEH14723.1 - 2.5e-18 65.8 0.4 5.9e-18 64.6 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH14723.1 - 5.1e-08 33.8 0.2 1.2e-06 29.4 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Abhydrolase_5 PF12695.2 CEH14723.1 - 2.1e-07 30.8 0.2 2.1e-06 27.5 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH14723.1 - 4.1e-05 23.2 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 CEH14723.1 - 0.024 13.5 0.1 0.055 12.3 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF2305 PF10230.4 CEH14723.1 - 0.029 13.8 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 CEH14723.1 - 0.046 13.9 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 CEH14723.1 - 0.13 11.8 0.0 0.91 9.1 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_3 PF07859.8 CEH14724.1 - 4.7e-19 68.8 0.8 2.5e-18 66.4 0.6 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CEH14724.1 - 2.3e-10 39.6 0.0 3.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CEH14724.1 - 2.9e-07 30.3 0.0 6.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH14724.1 - 0.0011 18.9 0.6 0.0016 18.4 0.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 CEH14724.1 - 0.0064 15.2 0.0 2.2 6.8 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.16 CEH14724.1 - 0.015 14.5 0.0 0.039 13.1 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase PF00151.14 CEH14724.1 - 0.038 13.2 0.0 0.088 12.0 0.0 1.5 2 0 0 2 2 2 0 Lipase BAAT_C PF08840.6 CEH14724.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SGL PF08450.7 CEH14725.1 - 0.013 14.9 0.0 3.4 6.9 0.0 2.9 2 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Nop14 PF04147.7 CEH14725.1 - 0.014 13.3 3.8 0.018 13.0 2.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CEH14725.1 - 0.014 13.4 3.4 0.021 12.9 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Ldl_recept_b PF00058.12 CEH14725.1 - 0.028 14.7 0.4 3.8 7.9 0.0 3.2 3 0 0 3 3 3 0 Low-density lipoprotein receptor repeat class B Sporozoite_P67 PF05642.6 CEH14725.1 - 0.13 10.1 0.7 0.2 9.4 0.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BAF1_ABF1 PF04684.8 CEH14725.1 - 0.19 10.5 4.8 0.27 10.0 3.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TRAP_alpha PF03896.11 CEH14725.1 - 1.3 7.9 3.7 1.9 7.4 2.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ketoacyl-synt PF00109.21 CEH14726.1 - 3.1e-53 180.8 0.7 3.1e-53 180.8 0.5 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 CEH14726.1 - 2e-39 135.1 2.5 7e-39 133.3 0.0 2.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 CEH14726.1 - 6.4e-33 114.0 0.1 6.4e-33 114.0 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 CEH14726.1 - 9.1e-30 102.9 0.7 2.1e-29 101.7 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 CEH14726.1 - 2.3e-12 46.9 0.0 4.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.18 CEH14726.1 - 8.1e-06 25.0 0.5 2.2e-05 23.6 0.4 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 CEH14726.1 - 0.00062 19.9 0.0 0.0018 18.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 CEH14726.1 - 0.16 10.6 0.0 0.4 9.3 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lipase_GDSL PF00657.17 CEH14727.1 - 5.2e-10 39.5 0.0 1.9e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Mcp5_PH PF12814.2 CEH14728.1 - 5.2e-38 129.7 0.0 1.1e-37 128.6 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology ZYG-11_interact PF05884.7 CEH14728.1 - 0.35 9.8 0.1 0.8 8.7 0.1 1.6 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF1664 PF07889.7 CEH14728.1 - 0.63 9.8 10.5 0.52 10.1 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 CEH14728.1 - 1.8 8.5 3.8 38 4.2 0.2 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IMS PF00817.15 CEH14729.1 - 1.2e-36 125.7 0.0 4.4e-36 123.9 0.0 1.8 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CEH14729.1 - 2.2e-06 27.5 0.0 1.1e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF2945 PF11160.3 CEH14730.1 - 0.045 13.5 3.7 0.071 12.9 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) Sec23_trunk PF04811.10 CEH14731.1 - 7.8e-73 244.8 0.0 1.2e-72 244.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CEH14731.1 - 2.6e-23 81.4 0.4 5.2e-23 80.4 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CEH14731.1 - 3.8e-16 58.3 8.2 7e-16 57.5 5.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CEH14731.1 - 1.2e-14 54.5 0.0 3.7e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CEH14731.1 - 0.00022 20.8 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WD40 PF00400.27 CEH14733.1 - 2.4e-72 236.4 12.9 6.1e-12 44.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CEH14733.1 - 7.3e-27 93.3 3.4 1.3e-26 92.6 2.3 1.4 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 CEH14733.1 - 0.00017 19.9 0.5 0.049 11.9 0.1 2.7 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 CEH14733.1 - 0.00036 19.3 0.3 0.9 8.2 0.0 3.1 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 CEH14733.1 - 0.00051 18.2 2.8 1.1 7.3 0.0 3.6 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 CEH14733.1 - 0.0024 17.0 0.9 6.4 5.7 0.0 4.1 2 2 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 CEH14733.1 - 0.0064 16.1 0.0 7.8 6.2 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat GAS PF13851.1 CEH14733.1 - 0.025 13.7 0.5 0.05 12.8 0.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3732 PF12532.3 CEH14733.1 - 0.066 12.7 0.1 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3732) DPPIV_N PF00930.16 CEH14733.1 - 0.13 10.7 0.0 9.5 4.6 0.0 2.8 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Phage_lysis PF03245.8 CEH14733.1 - 0.22 11.5 3.1 0.66 9.9 2.1 1.8 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Proteasome_A_N PF10584.4 CEH14733.1 - 0.69 9.2 3.9 30 4.0 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature AMP-binding PF00501.23 CEH14734.1 - 2.1e-11 42.8 0.1 2.8e-10 39.1 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme Glyco_hydro_47 PF01532.15 CEH14737.1 - 4.1e-51 174.0 0.0 2.5e-28 98.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Rod-binding PF10135.4 CEH14737.1 - 0.075 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Rod binding protein DUF2236 PF09995.4 CEH14738.1 - 0.081 12.1 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) DUF2236 PF09995.4 CEH14739.1 - 0.0011 18.3 0.1 0.0024 17.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) ICMT PF04140.9 CEH14740.1 - 4.9e-15 55.5 0.2 8.1e-14 51.5 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CEH14740.1 - 3.4e-11 43.1 0.4 4.3e-09 36.4 0.1 2.5 2 0 0 2 2 2 2 Phospholipid methyltransferase DUF1295 PF06966.7 CEH14740.1 - 0.02 14.2 0.1 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Ribosomal_S9 PF00380.14 CEH14741.1 - 2.9e-31 108.2 0.0 9.1e-31 106.6 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S9/S16 dCMP_cyt_deam_1 PF00383.17 CEH14742.1 - 1.2e-18 66.6 0.0 1.9e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CEH14742.1 - 0.0056 16.5 0.5 0.069 12.9 0.3 2.3 1 1 0 1 1 1 1 Bd3614-like deaminase AAA_33 PF13671.1 CEH14744.1 - 5.4e-15 55.5 0.3 1e-13 51.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain RNA_ligase PF09414.5 CEH14744.1 - 3.8e-08 33.3 0.0 6.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 RNA ligase Y_phosphatase PF00102.22 CEH14744.1 - 9e-05 21.9 0.0 0.0002 20.7 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase AAA_17 PF13207.1 CEH14744.1 - 0.00031 21.5 0.0 0.0056 17.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CEH14744.1 - 0.00047 19.3 0.0 0.00086 18.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DSPc PF00782.15 CEH14744.1 - 0.0048 16.4 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain IstB_IS21 PF01695.12 CEH14744.1 - 0.0069 15.8 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 CEH14744.1 - 0.0083 16.2 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 CEH14744.1 - 0.013 14.5 0.0 0.034 13.2 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_25 PF13481.1 CEH14744.1 - 0.048 13.0 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 CEH14744.1 - 0.053 13.1 0.2 5.4 6.6 0.0 2.4 1 1 1 2 2 2 0 Adenylylsulphate kinase CDKN3 PF05706.7 CEH14744.1 - 0.073 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 CEH14744.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family gerPA PF10676.4 CEH14745.1 - 1.8e-06 27.6 7.1 1.5 8.7 0.1 4.3 4 0 0 4 4 4 4 Spore germination protein gerPA/gerPF AAA_17 PF13207.1 CEH14746.1 - 0.0014 19.4 0.0 0.0097 16.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEH14746.1 - 0.039 13.8 1.4 0.41 10.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain BP28CT PF08146.7 CEH14746.1 - 0.043 13.5 0.5 4.9 6.8 0.0 2.7 3 0 0 3 3 3 0 BP28CT (NUC211) domain DinI PF06183.8 CEH14746.1 - 0.055 13.4 0.2 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 DinI-like family Peptidase_C50 PF03568.12 CEH14747.1 - 1.6e-84 283.8 0.0 3e-84 282.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 UCH_1 PF13423.1 CEH14749.1 - 5.6e-29 101.5 0.4 8.3e-29 100.9 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CEH14749.1 - 3.8e-21 76.0 0.0 2.8e-20 73.2 0.0 2.1 1 1 0 1 1 1 1 Exonuclease UCH PF00443.24 CEH14749.1 - 1.7e-05 24.0 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 CEH14749.1 - 0.061 13.2 5.2 8.9 6.3 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat cobW PF02492.14 CEH14750.1 - 2.1e-33 115.2 0.9 2.7e-33 114.8 0.6 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 CEH14750.1 - 0.0058 16.2 0.2 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 CEH14750.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain Viral_helicase1 PF01443.13 CEH14750.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 CEH14750.1 - 0.016 14.7 0.2 0.041 13.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 CEH14750.1 - 0.026 13.3 1.2 0.045 12.5 0.8 1.5 1 1 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 CEH14750.1 - 0.035 14.2 0.1 0.055 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CEH14750.1 - 0.053 12.6 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 CEH14750.1 - 0.055 12.3 0.3 0.072 11.9 0.2 1.3 1 1 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 CEH14750.1 - 0.061 13.0 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 CEH14750.1 - 0.074 12.9 0.2 0.12 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEH14750.1 - 0.077 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 CEH14750.1 - 0.11 11.1 0.1 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 CEH14750.1 - 0.12 11.9 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 CEH14751.1 - 1.8e-09 37.2 0.1 2.9e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 CEH14751.1 - 1.3e-07 31.2 0.1 0.0076 15.9 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain CDC45 PF02724.9 CEH14751.1 - 0.0022 16.1 0.0 0.0027 15.8 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 CEH14751.1 - 0.068 11.0 1.4 0.086 10.7 0.9 1.1 1 0 0 1 1 1 0 Nop14-like family Fer4_15 PF13459.1 CEH14751.1 - 2.3 8.8 7.6 2.5 8.7 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain Sugar_tr PF00083.19 CEH14754.1 - 1.5e-40 139.2 12.8 6.5e-38 130.4 5.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEH14754.1 - 4.2e-20 71.7 21.1 1.7e-10 40.2 4.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily SAPS PF04499.10 CEH14755.1 - 9.4e-134 446.6 0.0 1.9e-133 445.5 0.0 1.6 1 1 0 1 1 1 1 SIT4 phosphatase-associated protein Formyl_trans_N PF00551.14 CEH14755.1 - 9.8e-21 74.1 0.0 2.7e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Formyl transferase tRNA-synt_1 PF00133.17 CEH14756.1 - 2.4e-206 686.4 0.0 1.8e-205 683.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CEH14756.1 - 2.1e-38 131.4 0.2 2.1e-38 131.4 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CEH14756.1 - 2e-14 53.0 0.2 5.9e-06 25.1 0.0 4.9 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CEH14756.1 - 2.1e-08 33.7 0.0 3.7e-06 26.3 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 CEH14756.1 - 0.0035 16.2 0.0 0.024 13.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 CEH14756.1 - 0.0082 15.2 0.0 0.59 9.2 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.20 CEH14756.1 - 0.12 11.4 0.4 0.77 8.8 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) AAA PF00004.24 CEH14757.1 - 1.6e-15 57.5 0.0 2.5e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 CEH14757.1 - 6.4e-11 42.2 0.1 1.8e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 BCS1 N terminal DUF815 PF05673.8 CEH14757.1 - 0.0005 19.0 0.1 0.00084 18.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CEH14757.1 - 0.017 15.1 0.4 0.13 12.2 0.1 2.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 CEH14757.1 - 0.053 14.3 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 CEH14757.1 - 0.054 12.5 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CEH14757.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CEH14757.1 - 0.13 11.4 0.1 0.32 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Ank_2 PF12796.2 CEH14758.1 - 1e-12 48.1 0.1 1.4e-06 28.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEH14758.1 - 5.3e-10 39.2 0.1 1.3e-05 25.2 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEH14758.1 - 6.6e-10 39.2 0.0 5.6e-05 23.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CEH14758.1 - 4.8e-07 29.2 0.3 0.0024 17.6 0.2 4.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.1 CEH14758.1 - 0.00059 19.8 0.5 0.11 12.8 0.1 3.5 4 1 0 4 4 4 1 Ankyrin repeat DEAD PF00270.24 CEH14760.1 - 4e-42 143.5 0.2 6.1e-42 142.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH14760.1 - 1e-23 82.9 0.1 2.2e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CEH14760.1 - 0.059 12.4 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Acetyltransf_1 PF00583.19 CEH14761.1 - 4.8e-14 52.1 0.0 6.4e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEH14761.1 - 1.6e-05 24.9 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEH14761.1 - 0.00024 20.8 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CEH14761.1 - 0.00098 19.2 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Malate_synthase PF01274.17 CEH14764.1 - 1.7e-26 92.3 0.0 1.8e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Malate_synthase PF01274.17 CEH14765.1 - 6.5e-154 512.7 0.0 7.3e-154 512.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 CEH14765.1 - 0.0045 15.9 0.0 0.0068 15.3 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF1349 PF07081.6 CEH14766.1 - 4.9e-21 74.9 0.4 1.4e-20 73.3 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) PH_9 PF15410.1 CEH14767.1 - 6.1e-08 32.8 0.1 1.3e-06 28.5 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CEH14767.1 - 3.5e-07 30.3 0.0 7.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Nop14 PF04147.7 CEH14767.1 - 0.18 9.6 6.3 0.27 9.1 4.4 1.1 1 0 0 1 1 1 0 Nop14-like family PH_11 PF15413.1 CEH14767.1 - 0.46 10.7 0.7 11 6.3 0.5 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain CDC45 PF02724.9 CEH14767.1 - 5.8 4.8 7.0 9.1 4.1 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DEAD PF00270.24 CEH14768.1 - 7.8e-43 145.8 0.0 1.2e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CEH14768.1 - 5.9e-05 22.9 0.0 0.00022 21.1 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CEH14768.1 - 0.0007 18.4 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.4 CEH14768.1 - 0.016 14.2 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CEH14768.1 - 0.034 14.2 0.1 0.14 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF1281 PF06924.6 CEH14768.1 - 0.048 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) CMS1 PF14617.1 CEH14768.1 - 0.4 9.6 0.0 0.4 9.6 0.0 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit zf-met PF12874.2 CEH14769.1 - 6e-06 26.2 0.6 1e-05 25.5 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEH14769.1 - 3.3e-05 23.8 0.4 5.5e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 CEH14769.1 - 0.0053 16.5 2.9 0.0053 16.5 2.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1777) DUF2562 PF10814.3 CEH14769.1 - 0.16 11.9 2.2 0.33 10.8 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) Selenoprotein_S PF06936.6 CEH14769.1 - 1.3 8.4 14.4 1.4 8.3 2.6 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) efThoc1 PF11957.3 CEH14770.1 - 7.2e-88 295.2 0.9 1.5e-41 142.4 0.0 3.1 3 0 0 3 3 3 3 THO complex subunit 1 transcription elongation factor DUF3446 PF11928.3 CEH14770.1 - 0.43 10.7 12.2 1.3 9.2 8.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) TPT PF03151.11 CEH14772.1 - 5.5e-25 87.8 14.1 5.5e-25 87.8 9.7 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family Ninjurin PF04923.7 CEH14772.1 - 0.076 12.7 2.8 0.2 11.4 1.9 1.7 1 0 0 1 1 1 0 Ninjurin UAA PF08449.6 CEH14772.1 - 1.2 7.9 20.2 13 4.5 14.0 2.0 1 1 0 1 1 1 0 UAA transporter family Glyco_hydro_2_N PF02837.13 CEH14773.1 - 5.9e-23 81.2 0.1 1e-22 80.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 CEH14773.1 - 4.2e-15 55.4 0.0 9.2e-15 54.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 CEH14773.1 - 1.6e-09 38.1 0.0 5.4e-09 36.4 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Abhydrolase_5 PF12695.2 CEH14774.1 - 0.0011 18.7 0.1 0.0052 16.5 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH14774.1 - 0.0086 15.9 0.1 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Exo_endo_phos PF03372.18 CEH14775.1 - 6.6e-22 78.6 0.0 1.2e-21 77.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CEH14775.1 - 2.5e-09 36.5 9.5 0.00012 21.5 0.3 2.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEH14775.1 - 8.1e-07 28.7 0.9 0.00049 19.8 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CEH14775.1 - 0.00023 20.7 3.1 2 8.7 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CEH14775.1 - 0.015 15.4 4.4 2.2 8.8 0.1 3.9 3 0 0 3 3 3 0 Leucine rich repeat DHO_dh PF01180.16 CEH14777.1 - 4e-94 314.8 0.0 6.4e-94 314.2 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CEH14777.1 - 0.0063 15.3 0.7 0.061 12.1 0.0 2.6 3 0 0 3 3 3 1 FMN-dependent dehydrogenase ApoO PF09769.4 CEH14777.1 - 0.012 15.3 1.1 0.023 14.4 0.7 1.4 1 0 0 1 1 1 0 Apolipoprotein O Peptidase_M66 PF10462.4 CEH14777.1 - 0.037 12.8 0.6 0.059 12.2 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF972 PF06156.8 CEH14779.1 - 0.014 15.6 2.3 0.036 14.4 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Apolipoprotein PF01442.13 CEH14779.1 - 0.037 13.5 7.7 0.088 12.3 5.3 1.6 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain WEMBL PF05701.6 CEH14779.1 - 0.046 12.1 9.1 0.0037 15.8 3.0 1.5 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DivIVA PF05103.8 CEH14779.1 - 0.089 12.8 0.5 0.24 11.4 0.3 1.7 1 0 0 1 1 1 0 DivIVA protein TPR_MLP1_2 PF07926.7 CEH14779.1 - 0.12 12.1 5.1 0.27 10.9 3.5 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TIP120 PF08623.5 CEH14779.1 - 0.15 11.6 0.3 0.28 10.7 0.2 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Sec15 PF04091.7 CEH14779.1 - 0.21 10.9 1.2 0.36 10.0 0.8 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like YjcZ PF13990.1 CEH14779.1 - 0.29 10.2 4.4 0.52 9.3 3.1 1.3 1 0 0 1 1 1 0 YjcZ-like protein Prominin PF05478.6 CEH14779.1 - 0.35 8.3 3.8 0.52 7.7 2.6 1.1 1 0 0 1 1 1 0 Prominin DUF2968 PF11180.3 CEH14779.1 - 0.35 10.2 8.7 1 8.7 6.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) IFT57 PF10498.4 CEH14779.1 - 0.48 9.1 5.2 0.75 8.4 3.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AAA_13 PF13166.1 CEH14779.1 - 0.66 8.3 1.4 1.1 7.6 1.0 1.2 1 0 0 1 1 1 0 AAA domain DUF148 PF02520.12 CEH14779.1 - 0.86 9.4 3.7 1.6 8.5 2.0 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF148 DUF16 PF01519.11 CEH14779.1 - 1.1 9.5 3.7 1.4 9.1 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Rootletin PF15035.1 CEH14779.1 - 1.2 9.0 8.6 2.2 8.1 6.0 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Cluap1 PF10234.4 CEH14779.1 - 2.8 7.0 6.9 5.1 6.2 4.8 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 EMP24_GP25L PF01105.19 CEH14779.1 - 3.4 7.3 3.2 6.2 6.4 2.2 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Methyltransf_23 PF13489.1 CEH14780.1 - 2.1e-09 37.3 0.0 3.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH14780.1 - 8.8e-07 29.4 0.0 1.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH14780.1 - 7.9e-06 26.2 0.0 0.0058 17.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH14780.1 - 1.5e-05 25.0 0.2 4.9e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.1 CEH14780.1 - 2.4e-05 25.1 0.1 5.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH14780.1 - 0.00024 21.5 0.0 0.00097 19.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH14780.1 - 0.00048 19.7 0.0 0.016 14.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH14780.1 - 0.034 14.4 0.0 0.13 12.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF3419 PF11899.3 CEH14781.1 - 1.3e-133 445.3 0.0 1.7e-133 444.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 CEH14781.1 - 1.3e-09 37.9 0.0 1.3e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH14781.1 - 6.4e-08 32.8 0.0 1.2e-06 28.8 0.0 3.1 4 1 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH14781.1 - 9.4e-08 31.7 0.0 6.1e-07 29.1 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH14781.1 - 5.5e-07 29.9 0.0 1.7e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH14781.1 - 2.4e-06 27.9 0.0 2.2e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH14781.1 - 4.9e-06 27.1 0.0 2.1e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH14781.1 - 0.00015 21.7 0.0 0.0056 16.6 0.0 3.0 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEH14781.1 - 0.00043 19.4 0.0 0.00099 18.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CEH14781.1 - 0.0042 16.1 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_28 PF02636.12 CEH14781.1 - 0.088 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 CEH14781.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Med12-PQL PF12144.3 CEH14782.1 - 0.37 10.1 4.4 0.064 12.6 0.4 1.6 2 0 0 2 2 2 0 Eukaryotic Mediator 12 catenin-binding domain adh_short PF00106.20 CEH14783.1 - 2.7e-20 72.9 0.7 4e-20 72.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH14783.1 - 3e-06 27.0 0.2 4.7e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 CEH14783.1 - 0.022 14.6 0.4 0.06 13.1 0.1 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 CEH14783.1 - 0.12 12.8 0.7 0.23 11.8 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 CEH14784.1 - 2.7e-07 30.2 0.0 1.8e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH14784.1 - 0.04 13.6 0.2 0.52 10.0 0.1 2.8 3 1 1 4 4 4 0 Alcohol dehydrogenase GroES-like domain FTHFS PF01268.14 CEH14785.1 - 1e-261 868.8 0.1 1e-261 868.8 0.1 1.5 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CEH14785.1 - 3.2e-64 214.8 1.9 3.2e-64 214.8 1.3 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CEH14785.1 - 9.6e-36 122.3 0.0 8e-35 119.4 0.0 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Prefoldin PF02996.12 CEH14785.1 - 0.012 15.2 0.5 0.082 12.5 0.0 2.5 2 0 0 2 2 2 0 Prefoldin subunit Mito_carr PF00153.22 CEH14786.1 - 6.7e-66 218.0 4.7 7.6e-23 80.0 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GPP34 PF05719.6 CEH14787.1 - 5e-66 222.6 0.1 6.5e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Complex1_LYR_1 PF13232.1 CEH14788.1 - 3.1e-06 27.2 1.9 8e-06 25.9 1.3 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CEH14788.1 - 1.1e-05 25.0 2.5 2.9e-05 23.7 1.7 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) F-box PF00646.28 CEH14791.1 - 0.0018 17.8 0.3 0.0042 16.6 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CEH14791.1 - 0.0099 15.5 0.8 0.025 14.3 0.2 2.1 2 0 0 2 2 2 1 F-box-like NAD_binding_2 PF03446.10 CEH14793.1 - 0.059 13.2 0.0 0.068 13.0 0.0 1.0 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F-box-like PF12937.2 CEH14795.1 - 9.6e-06 25.2 0.2 9.6e-06 25.2 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEH14795.1 - 1.2e-05 24.7 1.0 3.7e-05 23.2 0.2 2.2 2 0 0 2 2 2 1 F-box domain FAM60A PF15396.1 CEH14795.1 - 1.8 8.2 4.1 26 4.4 0.1 3.5 3 1 1 4 4 4 0 Protein Family FAM60A F-box-like PF12937.2 CEH14796.1 - 9.3e-05 22.0 2.0 0.00019 21.1 0.5 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEH14796.1 - 0.00015 21.3 0.7 0.00029 20.4 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEH14799.1 - 6.5e-09 35.3 0.1 1.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH14799.1 - 2.4e-06 27.0 0.0 6.5e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain RVT_2 PF07727.9 CEH14800.1 - 6.4e-69 231.6 0.0 9.3e-69 231.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2744 PF10910.3 CEH14800.1 - 0.096 12.5 0.2 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2744) UBN2_2 PF14227.1 CEH14801.1 - 2.5e-07 30.2 0.0 3.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CEH14801.1 - 3.4e-05 23.6 0.0 5.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type eIF3g PF12353.3 CEH14801.1 - 0.039 13.8 0.1 0.074 12.9 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.1 CEH14801.1 - 0.087 12.3 2.1 0.17 11.3 1.5 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Dioxygenase_N PF04444.9 CEH14801.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Catechol dioxygenase N terminus F-box PF00646.28 CEH14802.1 - 0.0017 17.9 0.2 0.0074 15.9 0.0 2.2 2 0 0 2 2 2 1 F-box domain DMA PF03474.9 CEH14803.1 - 0.18 11.6 0.8 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif RVT_2 PF07727.9 CEH14805.1 - 3.4e-10 39.3 0.0 5.1e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_2 PF14227.1 CEH14805.1 - 3.4e-10 39.5 0.0 5.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CEH14805.1 - 9.8e-09 35.0 0.1 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CEH14805.1 - 1.2e-07 31.2 0.0 3.2e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_3 PF14244.1 CEH14805.1 - 3.5e-07 29.9 0.0 0.00062 19.3 0.0 2.4 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CEH14805.1 - 0.012 14.9 0.5 0.12 11.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) DOG1 PF14144.1 CEH14805.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Seed dormancy control zf-CCHC_4 PF14392.1 CEH14805.1 - 0.26 10.9 3.2 0.62 9.7 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle F-box PF00646.28 CEH14806.1 - 0.044 13.4 1.4 0.051 13.2 0.0 1.9 2 0 0 2 2 2 0 F-box domain PWI PF01480.12 CEH14807.1 - 4.1e-05 23.5 0.0 8.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 PWI domain SPT16 PF08644.6 CEH14807.1 - 0.16 11.8 0.3 0.54 10.0 0.2 1.9 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Med4 PF10018.4 CEH14808.1 - 6.8e-09 35.3 3.9 6.8e-09 35.3 2.7 1.8 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 HeLo PF14479.1 CEH14808.1 - 0.02 14.6 3.5 0.037 13.7 2.4 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation FlgN PF05130.7 CEH14808.1 - 0.065 13.4 5.0 0.38 11.0 3.4 2.2 1 1 0 1 1 1 0 FlgN protein F-box-like PF12937.2 CEH14810.1 - 9.4e-06 25.2 0.0 3e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH14810.1 - 0.00062 19.3 0.1 0.0027 17.2 0.0 2.1 2 0 0 2 2 2 1 F-box domain Fels1 PF05666.6 CEH14810.1 - 0.076 12.3 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like DUF2140 PF09911.4 CEH14810.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) F-box-like PF12937.2 CEH14811.1 - 0.00014 21.5 0.2 0.00032 20.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH14811.1 - 0.048 13.3 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 F-box domain F-box PF00646.28 CEH14812.1 - 2.9e-05 23.5 0.7 7e-05 22.3 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEH14812.1 - 0.0032 17.1 2.2 0.0035 17.0 0.5 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CEH14813.1 - 0.00028 20.4 0.4 0.00073 19.1 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEH14813.1 - 0.0015 18.1 0.5 0.0034 17.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH14814.1 - 1.3e-05 24.7 0.8 1.3e-05 24.7 0.6 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 CEH14814.1 - 6.6e-05 22.5 0.2 6.6e-05 22.5 0.2 2.4 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 CEH14816.1 - 1.4e-07 31.1 0.5 3.4e-07 29.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH14816.1 - 2.6e-05 23.7 1.3 5.5e-05 22.6 0.4 2.0 2 0 0 2 2 2 1 F-box domain WD40 PF00400.27 CEH14819.1 - 1.1e-13 50.5 1.7 1.9e-07 30.6 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat G-patch PF01585.18 CEH14822.1 - 1.1e-09 37.8 1.4 2.2e-09 36.9 0.9 1.5 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 CEH14822.1 - 0.0067 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEH14822.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH14822.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 CEH14823.1 - 4.6e-23 81.4 46.5 1.3e-16 60.2 18.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HMG_box_5 PF14887.1 CEH14824.1 - 4.4 7.1 6.5 8.3 6.2 0.5 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Gtr1_RagA PF04670.7 CEH14826.1 - 0.0075 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GBP PF02263.14 CEH14826.1 - 0.11 11.5 0.0 0.4 9.6 0.0 1.8 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain DUF4632 PF15451.1 CEH14828.1 - 0.038 13.9 0.1 0.063 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) TPR_6 PF13174.1 CEH14828.1 - 2.6 8.6 5.4 18 6.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CIA30 PF08547.7 CEH14831.1 - 3.3e-11 43.2 0.0 5.1e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) PX PF00787.19 CEH14832.1 - 0.0034 17.1 0.0 0.004 16.9 0.0 1.1 1 0 0 1 1 1 1 PX domain Hexapep PF00132.19 CEH14833.1 - 1.3e-14 52.9 7.7 1.1e-05 24.7 0.7 5.0 1 1 4 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CEH14833.1 - 0.0003 20.2 6.7 0.062 12.8 1.3 3.2 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase W2 PF02020.13 CEH14833.1 - 0.00051 19.9 0.6 0.00051 19.9 0.5 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Fucokinase PF07959.7 CEH14833.1 - 0.0056 15.2 1.3 0.017 13.7 0.6 1.9 1 1 1 2 2 2 1 L-fucokinase Nse4_C PF08743.5 CEH14834.1 - 2.1e-26 91.7 0.0 7.2e-26 90.0 0.0 2.0 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 CEH14834.1 - 1.2e-11 44.3 0.4 2.8e-11 43.0 0.3 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF3762 PF12591.3 CEH14834.1 - 0.053 13.5 0.6 0.11 12.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) DUF3140 PF11338.3 CEH14835.1 - 2e-31 107.9 1.2 2.4e-31 107.6 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) PAD PF03068.10 CEH14835.1 - 0.0071 14.8 0.2 0.0073 14.7 0.1 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Rep_4 PF05797.6 CEH14835.1 - 0.083 11.5 0.3 0.092 11.4 0.2 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Aminotran_1_2 PF00155.16 CEH14836.1 - 9.5e-31 107.0 0.0 2.7e-19 69.3 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEH14836.1 - 0.098 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase PseudoU_synth_1 PF01416.15 CEH14837.1 - 6e-19 68.4 0.0 4.1e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF1688 PF07958.6 CEH14838.1 - 3e-149 497.1 0.0 3.4e-149 496.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) WD40 PF00400.27 CEH14839.1 - 8.6e-16 57.1 15.0 8.1e-07 28.7 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat B3_4 PF03483.12 CEH14841.1 - 5.4e-23 81.3 0.0 8.8e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CEH14841.1 - 5.8e-18 64.4 0.0 1.2e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 CEH14841.1 - 0.0083 15.3 0.0 0.96 8.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Herpes_V23 PF01802.12 CEH14841.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Tfb4 PF03850.9 CEH14842.1 - 9.9e-57 192.2 8.0 4.3e-56 190.1 5.5 1.8 1 1 0 1 1 1 1 Transcription factor Tfb4 Bd3614-deam PF14439.1 CEH14842.1 - 0.0094 15.8 1.2 0.032 14.0 0.8 2.0 1 0 0 1 1 1 1 Bd3614-like deaminase HNH_2 PF13391.1 CEH14843.1 - 2.2e-06 27.3 0.0 4.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease LSM14 PF12701.2 CEH14846.1 - 2.2e-23 81.8 0.0 4.7e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 CEH14846.1 - 6.3e-10 39.5 0.1 0.00029 21.3 0.1 2.8 2 0 0 2 2 2 2 FDF domain SM-ATX PF14438.1 CEH14846.1 - 0.0045 16.8 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain CENP-I PF07778.6 CEH14847.1 - 7.9e-28 96.9 0.0 1.3e-24 86.2 0.0 2.3 2 0 0 2 2 2 2 Mis6 FLO_LFY PF01698.11 CEH14848.1 - 6.2 5.5 8.8 11 4.8 6.1 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein HSP70 PF00012.15 CEH14849.1 - 2.3e-266 884.5 4.5 2.7e-266 884.3 3.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEH14849.1 - 4.9e-15 54.9 0.1 1.4e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CEH14849.1 - 0.0032 17.2 0.2 0.4 10.5 0.0 3.0 2 2 0 2 2 2 1 Cell division protein FtsA Hydantoinase_A PF01968.13 CEH14849.1 - 0.0041 16.2 0.1 0.015 14.4 0.1 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CEH14849.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain CAF-1_p150 PF11600.3 CEH14851.1 - 0.00066 19.1 10.8 0.00066 19.1 7.5 3.0 3 0 0 3 3 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1510 PF07423.6 CEH14851.1 - 0.68 9.2 18.6 1.2 8.4 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Borrelia_P83 PF05262.6 CEH14851.1 - 1.1 7.4 25.3 0.59 8.3 8.8 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein Ycf1 PF05758.7 CEH14851.1 - 1.6 6.3 9.5 0.67 7.5 0.7 2.0 2 0 0 2 2 2 0 Ycf1 NAM-associated PF14303.1 CEH14851.1 - 2.3 8.4 37.8 0.13 12.5 8.5 2.5 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Glu_synthase PF01645.12 CEH14852.1 - 1.4e-158 527.6 0.2 2.6e-158 526.7 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CEH14852.1 - 2.2e-134 447.7 0.0 2.9e-134 447.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CEH14852.1 - 8.5e-118 392.7 0.0 1.3e-117 392.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 CEH14852.1 - 5.7e-68 227.9 1.2 1e-67 227.1 0.8 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 CEH14852.1 - 2.8e-23 81.6 1.0 4e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CEH14852.1 - 2.4e-18 66.7 0.0 6.8e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEH14852.1 - 3.4e-10 40.3 0.2 0.0017 18.4 0.0 3.3 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH14852.1 - 1.3e-09 37.9 0.1 5.1e-09 36.0 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CEH14852.1 - 5.8e-07 29.8 1.1 0.00028 21.2 0.1 3.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CEH14852.1 - 6.3e-07 28.8 0.1 2.4e-06 26.9 0.1 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 CEH14852.1 - 9.5e-06 24.3 0.2 4.7e-05 22.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 CEH14852.1 - 2.5e-05 23.3 1.2 7.2e-05 21.8 0.2 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CEH14852.1 - 0.0001 21.5 0.6 0.00019 20.6 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEH14852.1 - 0.00015 20.7 0.3 0.00036 19.4 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 CEH14852.1 - 0.00088 18.4 0.1 0.0021 17.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 CEH14852.1 - 0.0016 18.6 0.0 1.6 9.0 0.0 2.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 CEH14852.1 - 0.002 17.2 0.1 0.0054 15.8 0.1 1.7 1 0 0 1 1 1 1 Thi4 family AdoHcyase_NAD PF00670.16 CEH14852.1 - 0.0042 16.9 0.6 3.9 7.2 0.1 2.7 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMN_dh PF01070.13 CEH14852.1 - 0.0085 14.9 2.7 0.021 13.6 1.1 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase GATase_6 PF13522.1 CEH14852.1 - 0.009 15.9 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Lycopene_cycl PF05834.7 CEH14852.1 - 0.015 14.2 0.2 0.8 8.5 0.1 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 CEH14852.1 - 0.016 14.9 0.1 0.42 10.3 0.0 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 CEH14852.1 - 0.21 10.7 0.9 0.46 9.6 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.14 CEH14852.1 - 0.33 9.1 0.5 3 5.9 0.0 2.4 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like GIDA PF01134.17 CEH14852.1 - 0.41 9.4 2.9 0.28 9.9 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Peptidase_M3 PF01432.15 CEH14853.1 - 3.4e-133 445.0 0.0 4.7e-133 444.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 CEH14853.1 - 0.16 11.3 0.2 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Sporozoite_P67 PF05642.6 CEH14854.1 - 0.11 10.3 7.0 0.016 13.1 1.5 2.0 1 1 0 2 2 2 0 Sporozoite P67 surface antigen CorA PF01544.13 CEH14854.1 - 0.19 10.7 0.6 0.35 9.8 0.4 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein bZIP_C PF12498.3 CEH14854.1 - 0.26 12.5 3.5 0.14 13.3 0.7 1.9 2 0 0 2 2 2 0 Basic leucine-zipper C terminal CDC27 PF09507.5 CEH14854.1 - 0.96 8.6 6.5 0.45 9.6 1.0 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Peptidase_S24 PF00717.18 CEH14855.1 - 1.2e-07 31.2 0.0 2.3e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Cys_Met_Meta_PP PF01053.15 CEH14856.1 - 5.8e-152 505.4 0.0 6.6e-152 505.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CEH14856.1 - 5e-14 52.1 0.1 1.2e-13 50.8 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CEH14856.1 - 6.4e-11 41.8 0.0 9.8e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CEH14856.1 - 2.3e-09 36.5 0.1 3.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CEH14856.1 - 3.3e-07 29.7 0.0 5.5e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 CEH14856.1 - 0.004 15.6 0.0 0.0058 15.1 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Met_gamma_lyase PF06838.6 CEH14856.1 - 0.0044 15.3 0.0 0.0056 15.0 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 CEH14856.1 - 0.006 15.3 0.0 0.0077 14.9 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein NADH-G_4Fe-4S_3 PF10588.4 CEH14857.1 - 0.089 12.0 0.2 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region RBM39linker PF15519.1 CEH14857.1 - 0.15 12.3 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Zn_clus PF00172.13 CEH14858.1 - 1.8e-09 37.3 12.9 3.1e-09 36.5 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CEH14858.1 - 0.0067 15.3 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain JmjC PF02373.17 CEH14859.1 - 6.3e-38 129.5 0.2 1.3e-37 128.4 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 CEH14859.1 - 3.9e-15 55.0 0.2 1.3e-14 53.3 0.1 2.0 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.1 CEH14859.1 - 7e-12 45.3 0.1 2.5e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CEH14859.1 - 9.7e-11 41.6 0.2 3.3e-10 39.9 0.1 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain Cellulase PF00150.13 CEH14860.1 - 3.9e-17 62.3 3.3 6e-17 61.7 2.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.17 CEH14861.1 - 1.6e-41 142.3 0.0 2.5e-41 141.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 AvrPto PF11592.3 CEH14861.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto Abhydrolase_1 PF00561.15 CEH14862.1 - 4.8e-18 65.5 0.0 5.3e-13 49.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEH14862.1 - 0.0019 18.1 0.1 0.0048 16.7 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH14862.1 - 0.027 14.2 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family HLH PF00010.21 CEH14863.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FUSC PF04632.7 CEH14863.1 - 0.19 10.1 11.5 0.31 9.4 8.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Lzipper-MIP1 PF14389.1 CEH14863.1 - 0.32 11.1 2.4 0.73 9.9 0.3 2.2 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 MFS_1 PF07690.11 CEH14865.1 - 3.3e-35 121.4 20.5 3.3e-35 121.4 14.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH14865.1 - 2.2e-13 49.6 8.7 1.1e-12 47.3 6.0 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter AA_kinase PF00696.23 CEH14866.1 - 6.1e-27 94.7 0.4 8.6e-21 74.5 0.0 2.5 3 0 0 3 3 3 2 Amino acid kinase family Cys_Met_Meta_PP PF01053.15 CEH14867.1 - 6.3e-132 439.5 0.0 7.2e-132 439.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CEH14867.1 - 1.9e-10 40.0 0.0 3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CEH14867.1 - 9.3e-10 38.0 0.1 1.9e-08 33.7 0.0 2.3 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CEH14867.1 - 8.4e-08 31.5 0.0 1.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEH14867.1 - 0.00018 20.7 0.0 0.00058 19.0 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 CEH14867.1 - 0.062 11.5 0.0 0.098 10.9 0.0 1.4 1 0 0 1 1 1 0 Methionine gamma-lyase ATP_bind_1 PF03029.12 CEH14868.1 - 2.7e-62 210.4 0.0 8e-55 185.9 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CEH14868.1 - 0.0003 21.6 0.6 0.00065 20.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEH14868.1 - 0.0064 16.4 0.7 2 8.3 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 CEH14868.1 - 0.014 15.1 0.2 0.043 13.5 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CEH14868.1 - 0.052 13.1 0.1 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CEH14868.1 - 0.055 13.3 0.1 0.16 11.8 0.0 2.0 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 CEH14868.1 - 0.064 12.6 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 CEH14868.1 - 0.064 13.2 0.4 0.51 10.3 0.3 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CEH14868.1 - 0.12 11.4 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ArgK PF03308.11 CEH14868.1 - 0.13 10.9 0.1 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein LSM PF01423.17 CEH14869.1 - 1.2e-16 59.9 0.0 1.6e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CEH14869.1 - 7.9e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain RVT_2 PF07727.9 CEH14870.1 - 1.6e-69 233.6 0.0 2.2e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEH14870.1 - 4.3e-21 75.2 0.0 1.2e-20 73.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CEH14870.1 - 5.1e-11 42.0 0.6 1e-10 41.0 0.4 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 CEH14870.1 - 7.4e-09 35.2 0.0 1.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CEH14870.1 - 7.7e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CEH14870.1 - 0.0043 16.4 0.1 0.014 14.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.1 CEH14870.1 - 0.049 13.1 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain UBN2_3 PF14244.1 CEH14870.1 - 0.2 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DICT PF10069.4 CEH14872.1 - 0.092 12.2 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Sensory domain found in DIguanylate Cyclases & Two-component systems DFP PF04127.10 CEH14873.1 - 7.7e-05 22.3 0.0 9.2e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DUF2237 PF09996.4 CEH14873.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) DFP PF04127.10 CEH14874.1 - 0.0026 17.4 0.0 0.0032 17.0 0.0 1.1 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein YiaAB PF05360.9 CEH14875.1 - 0.095 12.2 0.2 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 yiaA/B two helix domain GFO_IDH_MocA PF01408.17 CEH14876.1 - 3.9e-14 53.1 0.0 7.3e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CEH14876.1 - 3.4e-10 39.7 0.0 7.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 CEH14876.1 - 0.00049 20.4 0.0 0.00095 19.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Peptidase_S10 PF00450.17 CEH14877.1 - 1.5e-70 238.4 0.0 2e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CEH14877.1 - 8.8e-06 25.7 0.0 4.6e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Zn_clus PF00172.13 CEH14880.1 - 3.3e-06 26.8 12.0 3.3e-06 26.8 8.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOZART1 PF12554.3 CEH14881.1 - 1.2e-12 47.1 0.1 1.5e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SSF PF00474.12 CEH14882.1 - 9.4e-13 47.5 30.7 2.6e-09 36.2 15.7 2.5 1 1 1 2 2 2 2 Sodium:solute symporter family 7tm_7 PF08395.7 CEH14882.1 - 0.041 12.9 0.1 0.041 12.9 0.1 2.7 3 1 1 4 4 4 0 7tm Chemosensory receptor YqeY PF09424.5 CEH14883.1 - 2.2e-30 105.4 4.9 2.7e-30 105.1 3.4 1.1 1 0 0 1 1 1 1 Yqey-like protein DUF928 PF06051.7 CEH14883.1 - 0.033 13.8 0.8 0.051 13.1 0.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) GatB_Yqey PF02637.13 CEH14883.1 - 0.035 13.8 4.2 0.1 12.3 2.9 1.9 1 1 0 1 1 1 0 GatB domain IKKbetaNEMObind PF12179.3 CEH14883.1 - 0.039 13.7 0.3 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Gp-FAR-1 PF05823.7 CEH14883.1 - 0.089 12.7 2.0 0.12 12.3 0.3 1.9 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Dak2 PF02734.12 CEH14883.1 - 0.65 9.6 7.9 0.21 11.2 0.6 2.1 1 1 1 2 2 2 0 DAK2 domain LPP20 PF02169.11 CEH14883.1 - 2.1 8.5 9.3 0.36 10.9 2.1 2.1 2 0 0 2 2 2 0 LPP20 lipoprotein ATE_C PF04377.10 CEH14884.1 - 5.3e-44 149.3 0.1 8.6e-44 148.6 0.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 CEH14884.1 - 2.2e-25 88.2 0.4 2.2e-25 88.2 0.3 1.8 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus tRNA_int_endo PF01974.12 CEH14886.1 - 3.6e-14 52.3 0.0 9.1e-14 51.0 0.0 1.6 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain COG4 PF08318.7 CEH14887.1 - 1.7e-53 181.5 0.0 7.8e-53 179.3 0.0 2.0 1 1 0 1 1 1 1 COG4 transport protein BRX_N PF13713.1 CEH14887.1 - 0.028 13.8 0.4 0.083 12.3 0.2 1.8 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain RINT1_TIP1 PF04437.8 CEH14887.1 - 0.03 12.8 0.1 0.079 11.5 0.0 1.7 2 0 0 2 2 2 0 RINT-1 / TIP-1 family HSCB_C PF07743.8 CEH14887.1 - 0.91 10.0 9.3 2 8.9 1.1 3.9 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Epimerase PF01370.16 CEH14888.1 - 9.7e-42 143.0 0.0 1.4e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CEH14888.1 - 2.4e-12 46.3 0.2 4.8e-08 32.2 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 CEH14888.1 - 1.2e-09 37.4 0.0 2.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CEH14888.1 - 1.6e-09 36.9 0.0 2.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CEH14888.1 - 6.3e-07 28.5 0.0 0.00041 19.3 0.0 2.6 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.20 CEH14888.1 - 0.0095 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CEH14888.1 - 0.024 14.6 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding tRNA-synt_1c PF00749.16 CEH14889.1 - 7.4e-86 287.6 0.3 1.6e-85 286.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain PRP4 PF08799.6 CEH14889.1 - 4.1 6.7 10.6 1.7 7.9 0.3 3.5 3 0 0 3 3 3 0 pre-mRNA processing factor 4 (PRP4) like DLIC PF05783.6 CEH14891.1 - 2e-45 155.3 0.0 4.2e-31 108.1 0.0 5.9 6 0 0 6 6 6 5 Dynein light intermediate chain (DLIC) AAA PF00004.24 CEH14891.1 - 0.00032 20.9 0.1 0.00067 19.8 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CEH14891.1 - 0.00036 20.0 0.1 0.017 14.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEH14891.1 - 0.0005 20.1 0.3 0.0033 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CEH14891.1 - 0.0028 17.7 0.3 0.016 15.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CEH14891.1 - 0.0061 16.2 0.1 0.021 14.5 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CEH14891.1 - 0.0078 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_28 PF13521.1 CEH14891.1 - 0.024 14.5 0.8 0.074 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CEH14891.1 - 0.024 14.3 0.0 0.065 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 CEH14891.1 - 0.027 13.4 0.1 0.045 12.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 CEH14891.1 - 0.027 14.7 0.1 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CEH14891.1 - 0.044 13.3 0.3 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CEH14891.1 - 0.045 14.5 0.1 0.15 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 CEH14891.1 - 0.078 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family IstB_IS21 PF01695.12 CEH14891.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 CEH14891.1 - 0.11 12.8 0.2 0.28 11.4 0.1 1.6 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 CEH14891.1 - 0.13 11.6 0.0 9.5 5.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DAP3 PF10236.4 CEH14891.1 - 0.19 10.6 0.1 0.42 9.5 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.14 CEH14891.1 - 0.19 11.1 0.2 0.72 9.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 CEH14891.1 - 0.24 11.9 0.2 0.72 10.3 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein DUF2763 PF10961.3 CEH14891.1 - 0.32 11.4 3.7 0.2 12.0 0.2 2.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2763) IFT43 PF15305.1 CEH14891.1 - 0.83 9.6 4.9 12 5.9 0.1 3.0 3 0 0 3 3 3 0 Intraflagellar transport protein 43 KAT11 PF08214.6 CEH14892.1 - 1.3e-29 103.3 0.0 4.9e-29 101.4 0.0 1.8 1 1 0 1 1 1 1 Histone acetylation protein CDC45 PF02724.9 CEH14892.1 - 6.6 4.6 5.5 2 6.3 0.0 2.0 1 1 1 2 2 2 0 CDC45-like protein zf-CHCC PF10276.4 CEH14893.1 - 4.2e-18 64.9 1.0 6.4e-18 64.3 0.7 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 CEH14893.1 - 0.0044 16.6 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-RING_2 PF13639.1 CEH14895.1 - 3.3e-09 36.4 5.3 3.3e-08 33.2 1.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEH14895.1 - 2.2e-06 27.5 5.6 1.1e-05 25.4 1.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH14895.1 - 5.7e-06 25.8 0.6 5.7e-06 25.8 0.4 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEH14895.1 - 6.3e-06 25.7 4.8 1.6e-05 24.4 1.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CEH14895.1 - 6.4e-06 26.1 0.7 2.5e-05 24.3 0.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CEH14895.1 - 9.9e-05 21.9 3.0 0.00033 20.3 0.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Rad50_zn_hook PF04423.9 CEH14895.1 - 0.0033 16.8 1.3 0.0057 16.1 0.2 1.9 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Apc11 PF12861.2 CEH14895.1 - 0.0058 16.4 0.4 0.012 15.4 0.0 1.6 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 CEH14895.1 - 0.016 14.6 0.9 0.016 14.6 0.6 1.7 2 0 0 2 2 2 0 P-11 zinc finger Prok-RING_4 PF14447.1 CEH14895.1 - 0.022 14.3 0.4 0.022 14.3 0.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.6 CEH14895.1 - 0.082 12.9 1.5 0.16 11.9 1.0 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 CEH14895.1 - 0.13 11.8 3.6 0.049 13.2 0.4 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Elong_Iki1 PF10483.4 CEH14895.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 FANCL_C PF11793.3 CEH14895.1 - 0.3 11.0 5.0 0.71 9.8 2.0 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-AN1 PF01428.11 CEH14896.1 - 3.1e-19 68.5 21.2 5.4e-11 42.1 4.7 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CEH14896.1 - 0.071 13.3 17.0 0.051 13.7 3.2 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain 4HBT PF03061.17 CEH14897.1 - 1.9e-09 37.5 0.1 3.2e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Ribosomal_L36e PF01158.13 CEH14898.1 - 1.5e-35 121.1 5.3 1.7e-35 120.9 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 CEH14898.1 - 0.052 12.6 0.2 0.06 12.4 0.1 1.1 1 0 0 1 1 1 0 LemA family L51_S25_CI-B8 PF05047.11 CEH14899.1 - 4.3e-12 45.5 0.0 5.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain FAD_binding_3 PF01494.14 CEH14900.1 - 1.2e-53 182.4 0.1 1.4e-52 178.9 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 CEH14900.1 - 3.7e-18 65.7 0.0 6.5e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 CEH14900.1 - 5.6e-06 25.4 0.0 1.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CEH14900.1 - 1e-05 24.2 0.0 1.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 CEH14900.1 - 2e-05 23.6 0.3 5.2e-05 22.2 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CEH14900.1 - 3.6e-05 23.7 0.0 9.7e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEH14900.1 - 9.9e-05 22.2 0.2 0.00048 20.0 0.1 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEH14900.1 - 0.00044 19.2 0.1 0.00073 18.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CEH14900.1 - 0.00056 19.0 0.0 0.00097 18.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 CEH14900.1 - 0.004 16.9 0.1 0.0082 15.9 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CEH14900.1 - 0.0059 16.6 0.1 0.019 15.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CEH14900.1 - 0.0069 15.0 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 CEH14900.1 - 0.019 15.3 0.1 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEH14900.1 - 0.02 14.0 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 CEH14900.1 - 0.055 12.3 0.1 0.1 11.4 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.13 CEH14900.1 - 0.17 11.8 0.1 0.41 10.6 0.0 1.7 2 0 0 2 2 1 0 TrkA-N domain DSPc PF00782.15 CEH14902.1 - 0.00073 19.1 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CEH14902.1 - 0.00084 19.6 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CEH14902.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CEH14902.1 - 0.012 15.0 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase E1-E2_ATPase PF00122.15 CEH14903.1 - 9.1e-53 178.6 3.8 2.5e-52 177.2 2.6 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEH14903.1 - 1.5e-35 122.3 14.3 2.5e-34 118.4 2.6 3.2 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEH14903.1 - 6.2e-27 95.4 0.0 2.5e-26 93.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEH14903.1 - 1.3e-14 53.4 0.0 3.3e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CEH14903.1 - 2.1e-14 54.1 0.0 5.2e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEH14903.1 - 8.7e-12 44.8 0.0 1.6e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CEH14903.1 - 8.1e-05 22.3 0.2 0.00014 21.5 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.4 CEH14903.1 - 0.006 16.1 1.5 0.025 14.1 0.1 2.6 2 1 0 2 2 2 1 Predicted membrane protein (DUF2157) Transket_pyr PF02779.19 CEH14905.1 - 3.1e-32 111.4 0.0 6.3e-32 110.5 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CEH14905.1 - 2.7e-23 82.2 0.0 5.5e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aldo_ket_red PF00248.16 CEH14906.1 - 1.6e-53 181.3 0.1 2.6e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L10 PF00466.15 CEH14906.1 - 8.6e-06 25.6 0.0 4.4e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L10 Herpes_UL6 PF01763.11 CEH14906.1 - 0.14 10.2 0.0 0.22 9.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Dna2 PF08696.6 CEH14908.1 - 2.6e-23 82.4 0.0 6e-15 55.1 0.0 3.4 3 0 0 3 3 3 3 DNA replication factor Dna2 Myc_target_1 PF15179.1 CEH14908.1 - 0.42 10.1 9.7 0.81 9.2 6.7 1.5 1 0 0 1 1 1 0 Myc target protein 1 AAA_11 PF13086.1 CEH14909.1 - 6.6e-41 140.4 0.6 2e-20 73.3 0.1 2.0 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 CEH14909.1 - 4.2e-15 55.8 0.0 1.2e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH14909.1 - 1.1e-08 34.6 0.2 2.3e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CEH14909.1 - 1.8e-06 27.6 0.1 0.028 13.9 0.0 2.1 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 CEH14909.1 - 2.7e-06 27.5 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 CEH14909.1 - 1.8e-05 24.4 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 CEH14909.1 - 2e-05 24.1 0.2 3.3e-05 23.4 0.1 1.5 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain Helicase_RecD PF05127.9 CEH14909.1 - 3.8e-05 23.3 0.0 7.2e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Helicase CbiA PF01656.18 CEH14909.1 - 0.00015 21.2 0.1 0.00028 20.3 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 CEH14909.1 - 0.0006 19.9 0.1 0.0015 18.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 CEH14909.1 - 0.0006 19.2 0.2 0.0013 18.1 0.0 1.5 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ArgK PF03308.11 CEH14909.1 - 0.0014 17.4 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 ArgK protein DUF2075 PF09848.4 CEH14909.1 - 0.0029 16.6 0.0 0.0063 15.5 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 CEH14909.1 - 0.0034 16.4 0.0 0.065 12.1 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_5 PF07728.9 CEH14909.1 - 0.0035 17.0 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CEH14909.1 - 0.0051 16.6 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CEH14909.1 - 0.0058 15.5 0.0 0.0083 15.0 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 CEH14909.1 - 0.0058 16.8 0.3 0.011 15.9 0.2 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 CEH14909.1 - 0.0076 14.9 0.0 0.01 14.4 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 CEH14909.1 - 0.0091 16.2 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CEH14909.1 - 0.011 15.5 0.1 0.033 14.0 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 CEH14909.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 CEH14909.1 - 0.015 14.7 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CEH14909.1 - 0.027 13.9 0.0 0.063 12.7 0.0 1.5 1 1 1 2 2 2 0 AAA-like domain AAA_25 PF13481.1 CEH14909.1 - 0.029 13.7 0.1 0.06 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CEH14909.1 - 0.037 13.1 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.12 CEH14909.1 - 0.053 13.0 0.1 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 CEH14909.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CEH14909.1 - 0.072 12.3 0.0 0.65 9.1 0.0 2.1 1 1 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.16 CEH14909.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.5 CEH14909.1 - 0.079 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 6PF2K PF01591.13 CEH14909.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase LpxK PF02606.9 CEH14909.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase ABC_tran PF00005.22 CEH14909.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.12 CEH14909.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_17 PF13207.1 CEH14909.1 - 0.2 12.5 0.9 0.35 11.7 0.6 1.5 1 1 0 1 1 1 0 AAA domain AAA_12 PF13087.1 CEH14910.1 - 8.5e-25 87.3 0.3 1.2e-24 86.8 0.2 1.2 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.1 CEH14910.1 - 0.047 13.1 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Atx10homo_assoc PF09759.4 CEH14911.1 - 1.1e-05 25.0 0.1 0.0011 18.6 0.0 3.3 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain CcdA PF07362.7 CEH14912.1 - 0.1 12.4 0.4 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA DBR1 PF05011.8 CEH14913.1 - 2.6e-22 79.2 0.1 2.7e-20 72.7 0.1 3.1 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CEH14913.1 - 1.8e-07 30.7 0.4 3.6e-07 29.7 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEH14913.1 - 0.00037 20.3 0.0 0.001 18.8 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain E1-E2_ATPase PF00122.15 CEH14914.1 - 4.2e-59 199.3 0.4 9e-59 198.2 0.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEH14914.1 - 1.7e-46 158.0 17.9 2.6e-39 134.6 2.8 2.8 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEH14914.1 - 8.9e-24 85.0 0.0 1.2e-22 81.4 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEH14914.1 - 5e-18 64.8 0.0 1.2e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEH14914.1 - 9.5e-12 45.4 0.0 3.2e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEH14914.1 - 4.7e-09 35.5 0.3 3.5e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEH14914.1 - 0.0019 17.8 0.4 0.026 14.0 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cyclin_N PF00134.18 CEH14915.1 - 1.1e-09 37.9 0.0 2.5e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CEH14915.1 - 0.09 12.7 2.2 13 5.7 0.1 2.7 2 2 0 2 2 2 0 Cyclin, C-terminal domain XPG_I PF00867.13 CEH14917.1 - 6.5e-27 93.4 0.0 1.8e-26 92.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CEH14917.1 - 2.5e-23 82.2 0.0 5e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CEH14917.1 - 1e-05 25.1 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing ATP-synt_C PF00137.16 CEH14918.1 - 3.6e-31 106.8 29.0 1.8e-18 66.1 6.6 3.0 3 0 0 3 3 3 2 ATP synthase subunit C NOC3p PF07540.6 CEH14919.1 - 1.6e-21 76.3 0.0 5.4e-21 74.6 0.0 2.0 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 CEH14919.1 - 4e-15 55.6 1.3 1.5e-14 53.7 0.0 2.5 3 0 0 3 3 3 1 CBF/Mak21 family Mito_carr PF00153.22 CEH14923.1 - 5.1e-31 106.2 1.8 7.6e-15 54.3 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Peptidase_C13 PF01650.13 CEH14924.1 - 1.7e-42 145.5 0.1 2.2e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family CobS_N PF12556.3 CEH14926.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal MFS_1 PF07690.11 CEH14927.1 - 1.8e-23 82.8 20.0 9.2e-12 44.3 3.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2140 PF09911.4 CEH14927.1 - 0.14 11.3 0.0 0.39 9.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) MMS22L_N PF14910.1 CEH14928.1 - 0.031 12.5 0.0 0.036 12.3 0.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal Pyr_redox PF00070.22 CEH14929.1 - 3.2e-15 56.2 0.0 1.5e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEH14929.1 - 1.2e-09 38.3 0.0 2.3e-05 24.3 0.0 4.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEH14929.1 - 7.5e-06 26.1 0.1 0.33 10.9 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CEH14929.1 - 1.6e-05 24.0 0.0 0.0083 15.0 0.0 2.5 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 CEH14929.1 - 0.0035 16.0 0.0 4 5.9 0.0 3.2 3 0 0 3 3 3 2 Tryptophan halogenase Abhydrolase_5 PF12695.2 CEH14929.1 - 0.0087 15.8 0.4 0.38 10.4 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF4224 PF13986.1 CEH14930.1 - 0.17 11.4 0.5 0.51 9.9 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) Cpn60_TCP1 PF00118.19 CEH14932.1 - 5.6e-130 434.2 0.0 6.4e-130 434.0 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RTA1 PF04479.8 CEH14933.1 - 4.3e-34 117.9 3.0 8.5e-34 117.0 2.1 1.4 1 1 0 1 1 1 1 RTA1 like protein Fungal_trans PF04082.13 CEH14934.1 - 4.4e-06 25.7 1.0 8.4e-06 24.8 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.14 CEH14935.1 - 3.4e-08 32.1 0.0 9e-06 24.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CEH14935.1 - 5.5e-05 23.3 0.0 0.00018 21.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CEH14935.1 - 0.0016 18.0 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 CEH14935.1 - 0.0037 17.1 0.0 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CEH14935.1 - 0.0071 15.2 1.2 0.01 14.6 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 CEH14935.1 - 0.016 15.0 0.1 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding DEAD PF00270.24 CEH14936.1 - 7.5e-39 132.9 0.0 5.9e-38 130.0 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH14936.1 - 2.8e-29 100.7 0.0 3.9e-25 87.5 0.0 3.0 2 1 1 3 3 3 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 CEH14936.1 - 0.00062 18.6 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CEH14936.1 - 0.0094 15.8 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1212 PF06738.7 CEH14937.1 - 4.2e-41 140.5 2.8 4.2e-41 140.5 1.9 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CEH14937.1 - 1.3e-20 73.6 3.7 1.3e-20 73.6 2.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Dak1 PF02733.12 CEH14941.1 - 3e-106 354.6 0.0 7.2e-106 353.4 0.0 1.5 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.12 CEH14941.1 - 5e-40 137.0 7.2 8.8e-40 136.2 5.0 1.4 1 0 0 1 1 1 1 DAK2 domain DNA_primase_lrg PF04104.9 CEH14943.1 - 1.3e-80 270.4 0.0 1.9e-80 269.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Mis14 PF08641.7 CEH14944.1 - 6.1e-07 29.5 3.0 1.2e-06 28.6 2.1 1.5 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Thioredoxin_4 PF13462.1 CEH14945.1 - 2.5e-10 40.6 0.0 6.1e-08 32.8 0.0 2.4 1 1 0 1 1 1 1 Thioredoxin PC_rep PF01851.17 CEH14946.1 - 1.9e-17 62.4 15.8 0.00033 20.7 0.1 8.2 7 0 0 7 7 7 6 Proteasome/cyclosome repeat TPR_5 PF12688.2 CEH14946.1 - 0.034 14.1 1.1 0.29 11.1 0.0 2.9 3 0 0 3 3 3 0 Tetratrico peptide repeat Nop PF01798.13 CEH14947.1 - 5.7e-56 187.9 1.0 5.7e-56 187.9 0.7 2.1 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 CEH14947.1 - 8.6e-26 89.5 0.0 1.4e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CEH14947.1 - 3.2e-14 52.8 0.1 3.2e-14 52.8 0.1 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DASH_Dad1 PF08649.5 CEH14948.1 - 6.7e-18 64.1 0.0 8.4e-18 63.8 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 SBDS_C PF09377.5 CEH14949.1 - 2e-41 140.5 0.1 4.7e-41 139.3 0.0 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 CEH14949.1 - 1.7e-30 104.6 0.8 2.8e-30 103.9 0.6 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein MCM PF00493.18 CEH14950.1 - 2.3e-138 460.5 0.0 3.2e-138 460.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 CEH14950.1 - 6.7e-32 110.6 31.9 6.7e-32 110.6 22.1 2.9 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CEH14950.1 - 2.2e-18 66.8 0.0 5.5e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CEH14950.1 - 2.9e-08 33.1 0.0 1.1e-06 27.9 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CEH14950.1 - 8.9e-06 25.4 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CEH14950.1 - 0.00077 19.0 0.1 0.0038 16.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CEH14950.1 - 0.022 14.2 0.1 0.16 11.4 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 CEH14950.1 - 0.095 12.8 0.0 0.33 11.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn_ribbon_2 PF12674.2 CEH14950.1 - 0.098 13.0 0.5 0.24 11.7 0.3 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain DSS1_SEM1 PF05160.8 CEH14951.1 - 5.2e-20 70.9 9.2 2.7e-12 46.2 1.7 2.2 2 0 0 2 2 2 2 DSS1/SEM1 family LSM PF01423.17 CEH14952.1 - 1.5e-14 53.2 0.2 2e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain SynMuv_product PF06047.6 CEH14954.1 - 2.9e-46 155.5 4.4 2.9e-46 155.5 3.1 2.4 2 0 0 2 2 2 1 Ras-induced vulval development antagonist CDC27 PF09507.5 CEH14954.1 - 3.7 6.6 33.4 0.1 11.7 17.9 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 TPR_19 PF14559.1 CEH14955.1 - 4.9e-05 23.5 5.9 4.9e-05 23.5 4.1 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat F-box-like PF12937.2 CEH14955.1 - 7.5e-05 22.3 1.1 0.00017 21.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like TPR_11 PF13414.1 CEH14955.1 - 0.00026 20.5 2.0 0.00026 20.5 1.4 2.1 2 0 0 2 2 2 1 TPR repeat F-box PF00646.28 CEH14955.1 - 0.0011 18.5 0.2 0.0011 18.5 0.1 2.4 3 0 0 3 3 3 1 F-box domain TPR_14 PF13428.1 CEH14955.1 - 0.017 15.6 7.9 0.051 14.2 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CEH14955.1 - 0.087 13.5 7.7 0.48 11.1 5.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEH14955.1 - 2 8.5 6.1 2.5 8.2 0.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CEH14955.1 - 2.1 8.7 4.4 1.4 9.2 0.3 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.17 CEH14956.1 - 1.1e-12 47.3 0.0 2.6e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH14956.1 - 6e-11 42.1 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH14956.1 - 2.1e-09 37.0 0.8 3.5e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_BLLF1 PF05109.8 CEH14956.1 - 0.53 8.1 8.4 0.65 7.8 5.9 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Nuf2 PF03800.9 CEH14957.1 - 2.5e-33 115.1 0.0 7e-33 113.6 0.0 1.7 1 0 0 1 1 1 1 Nuf2 family MerR-DNA-bind PF09278.6 CEH14957.1 - 0.22 11.9 10.7 0.12 12.7 0.8 3.7 2 1 1 3 3 3 0 MerR, DNA binding Reo_sigmaC PF04582.7 CEH14957.1 - 0.64 9.1 2.4 17 4.4 0.7 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein AbiH PF14253.1 CEH14957.1 - 9.3 5.7 9.2 2.1 7.9 1.7 2.3 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH Ribosomal_L29 PF00831.18 CEH14958.1 - 2.8e-18 65.3 1.6 2.8e-18 65.3 1.1 1.9 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 CEH14958.1 - 0.01 16.0 2.1 0.016 15.4 1.4 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 zf-C2H2_jaz PF12171.3 CEH14958.1 - 0.13 12.4 1.4 0.33 11.1 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RNA_pol_Rpb2_4 PF04566.8 CEH14958.1 - 1 9.2 3.5 2.1 8.2 0.9 2.2 2 1 0 2 2 2 0 RNA polymerase Rpb2, domain 4 HTH_12 PF08461.5 CEH14958.1 - 1.2 8.9 5.7 0.34 10.6 1.6 1.9 2 1 0 2 2 2 0 Ribonuclease R winged-helix domain Ribosomal_L18e PF00828.14 CEH14959.1 - 5.2e-24 85.0 1.3 8e-24 84.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 HMG_box_2 PF09011.5 CEH14961.1 - 0.29 11.5 2.1 0.64 10.4 0.0 2.5 3 0 0 3 3 3 0 HMG-box domain DUF4047 PF13256.1 CEH14963.1 - 0.022 14.7 0.6 0.084 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) WHEP-TRS PF00458.15 CEH14963.1 - 0.029 14.0 9.8 0.1 12.3 0.2 3.2 4 0 0 4 4 4 0 WHEP-TRS domain Oxidored_molyb PF00174.14 CEH14964.1 - 3.8e-26 91.5 0.0 5.7e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CEH14964.1 - 9.6e-11 41.4 0.2 5.3e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Mo-co oxidoreductase dimerisation domain Calcipressin PF04847.7 CEH14965.1 - 4e-28 98.2 0.0 6.8e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Calcipressin Voldacs PF03517.8 CEH14965.1 - 2.7e-21 75.8 1.8 1.5e-20 73.4 1.2 2.1 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Sugar_tr PF00083.19 CEH14966.1 - 1.9e-56 191.5 2.3 1.1e-53 182.3 0.4 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEH14966.1 - 1.3e-17 63.6 9.2 2.7e-17 62.5 6.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CEH14966.1 - 0.0059 15.0 0.2 0.0059 15.0 0.1 1.7 2 0 0 2 2 2 1 MFS/sugar transport protein DUF1228 PF06779.9 CEH14966.1 - 8.5 6.4 9.5 1.2 9.1 1.8 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1228) Macoilin PF09726.4 CEH14968.1 - 0.15 10.2 6.8 0.2 9.9 4.7 1.3 1 0 0 1 1 1 0 Transmembrane protein Snf7 PF03357.16 CEH14969.1 - 1.4e-33 115.7 18.0 1.6e-33 115.5 12.5 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 CEH14969.1 - 0.047 13.0 5.0 0.06 12.7 3.4 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway VWA PF00092.23 CEH14969.1 - 0.16 11.6 0.6 0.26 10.9 0.4 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain YlqD PF11068.3 CEH14969.1 - 0.16 11.9 11.3 0.2 11.6 7.3 1.5 1 1 1 2 2 2 0 YlqD protein DUF3138 PF11336.3 CEH14969.1 - 0.26 9.4 2.5 0.31 9.1 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) IncA PF04156.9 CEH14969.1 - 0.36 10.4 4.0 0.5 9.9 2.8 1.2 1 0 0 1 1 1 0 IncA protein KxDL PF10241.4 CEH14969.1 - 0.86 9.5 6.2 4.4 7.2 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein TPR_MLP1_2 PF07926.7 CEH14969.1 - 0.97 9.1 11.1 1.7 8.3 7.7 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ATP-synt_B PF00430.13 CEH14969.1 - 1.7 8.4 12.1 2.1 8.1 8.1 1.3 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF972 PF06156.8 CEH14969.1 - 2.5 8.4 8.1 1.6 9.1 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Remorin_C PF03763.8 CEH14969.1 - 7.1 6.2 13.0 2.5 7.6 6.6 1.9 1 1 1 2 2 2 0 Remorin, C-terminal region HMG_box PF00505.14 CEH14970.1 - 1.2e-08 35.0 3.5 1.2e-08 35.0 2.4 2.9 2 0 0 2 2 2 1 HMG (high mobility group) box Myb_DNA-binding PF00249.26 CEH14970.1 - 2.1e-08 34.0 0.2 4.3e-08 33.0 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain HMG_box_2 PF09011.5 CEH14970.1 - 1.2e-05 25.5 7.3 1.8e-05 25.0 3.6 2.6 2 0 0 2 2 2 1 HMG-box domain Nitroreductase PF00881.19 CEH14972.1 - 3.2e-28 98.6 0.1 6.7e-28 97.5 0.1 1.5 1 1 0 1 1 1 1 Nitroreductase family HbrB PF08539.6 CEH14973.1 - 2.6e-39 134.6 0.0 5.8e-39 133.4 0.0 1.6 1 1 0 1 1 1 1 HbrB-like His_Phos_1 PF00300.17 CEH14973.1 - 6e-26 91.4 0.1 1.6e-25 90.0 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Arf PF00025.16 CEH14974.1 - 1.6e-15 56.7 0.0 6.7e-13 48.2 0.0 2.6 1 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 CEH14974.1 - 2.8e-06 26.2 0.3 0.002 16.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.1 CEH14974.1 - 5.3e-06 26.5 1.0 4.7e-05 23.4 0.7 2.0 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 CEH14974.1 - 0.001 18.2 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CEH14974.1 - 0.0046 16.1 0.0 0.013 14.6 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CEH14974.1 - 0.0066 15.8 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 1 Ras family DAP3 PF10236.4 CEH14974.1 - 0.032 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 CEH14974.1 - 0.04 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CEH14974.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CEH14974.1 - 0.096 12.9 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter eRF1_2 PF03464.10 CEH14976.1 - 6.4e-43 146.2 0.0 1.2e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CEH14976.1 - 2.2e-35 121.3 0.2 4.8e-35 120.2 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CEH14976.1 - 2.1e-23 82.3 0.0 6.7e-23 80.7 0.0 1.8 1 1 0 1 1 1 1 eRF1 domain 1 Flavodoxin_NdrI PF07972.6 CEH14976.1 - 0.076 12.9 0.1 0.56 10.1 0.1 2.2 1 1 0 1 1 1 0 NrdI Flavodoxin like Ribosomal_L7Ae PF01248.21 CEH14976.1 - 0.096 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L7Ae PF01248.21 CEH14977.1 - 4.5e-14 51.7 0.2 5.3e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4605 PF15378.1 CEH14977.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) DUF605 PF04652.11 CEH14978.1 - 0.0038 16.6 6.0 0.0051 16.2 4.2 1.2 1 0 0 1 1 1 1 Vta1 like Cwf_Cwc_15 PF04889.7 CEH14978.1 - 0.3 10.7 15.6 0.47 10.1 3.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Rotamase PF00639.16 CEH14979.1 - 9.9e-19 67.8 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CEH14979.1 - 1.5e-15 57.4 0.0 2.2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CEH14979.1 - 6.3e-07 29.1 0.4 1.6e-06 27.8 0.2 1.7 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 CEH14979.1 - 0.029 15.0 0.0 0.038 14.6 0.0 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain DUF759 PF05537.6 CEH14979.1 - 0.083 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) DUF2205 PF10224.4 CEH14981.1 - 1.1e-11 44.1 0.3 1.6e-11 43.6 0.2 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Med30 PF11315.3 CEH14981.1 - 0.024 14.7 0.1 0.028 14.5 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 30 DP PF08781.5 CEH14981.1 - 0.032 13.9 0.1 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcription factor DP Sec2p PF06428.6 CEH14981.1 - 0.041 13.7 1.6 0.092 12.5 1.0 1.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF972 PF06156.8 CEH14981.1 - 0.093 13.0 0.3 0.12 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Pro_Al_protease PF02983.9 CEH14981.1 - 6.9 6.7 7.0 1.3 9.0 1.3 2.1 2 1 0 2 2 2 0 Alpha-lytic protease prodomain Ribosomal_S16 PF00886.14 CEH14986.1 - 8.8e-24 82.9 0.1 1.9e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S16 Uso1_p115_C PF04871.8 CEH14986.1 - 0.19 11.6 3.7 0.32 10.9 2.6 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CsbD PF05532.7 CEH14987.1 - 0.0022 17.6 5.0 0.0022 17.6 3.5 1.7 1 1 0 1 1 1 1 CsbD-like Vps51 PF08700.6 CEH14989.1 - 5.3e-18 64.6 0.4 1.2e-17 63.5 0.3 1.5 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 CEH14989.1 - 0.00015 21.7 0.7 0.00023 21.1 0.5 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 CEH14989.1 - 0.00015 20.3 1.0 0.00021 19.8 0.7 1.1 1 0 0 1 1 1 1 Dor1-like family DUF3086 PF11285.3 CEH14989.1 - 0.03 13.1 0.2 0.042 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) FlgN PF05130.7 CEH14989.1 - 0.031 14.5 4.6 0.27 11.4 0.6 2.2 1 1 1 2 2 2 0 FlgN protein LIF_OSM PF01291.12 CEH14989.1 - 0.042 13.7 0.2 0.064 13.1 0.2 1.2 1 0 0 1 1 1 0 LIF / OSM family FUSC PF04632.7 CEH14989.1 - 2.9 6.2 10.1 4 5.7 7.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FYVE PF01363.16 CEH14990.1 - 1.9e-16 59.7 3.5 3.3e-16 58.9 2.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-DHHC PF01529.15 CEH14990.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase DEAD PF00270.24 CEH14991.1 - 9.7e-42 142.3 0.0 2e-41 141.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CEH14991.1 - 1.3e-24 85.5 0.1 2.5e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CEH14991.1 - 7.5e-21 73.7 0.0 1.7e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH14991.1 - 0.0015 18.3 0.0 0.0049 16.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CEH14991.1 - 0.0037 17.2 0.9 0.0059 16.5 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain CPSF73-100_C PF11718.3 CEH14992.1 - 5.4e-49 166.4 0.2 9.6e-47 159.1 0.0 2.5 3 0 0 3 3 3 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CEH14992.1 - 6.9e-31 106.8 0.0 1.6e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 CEH14992.1 - 1.5e-14 54.1 0.0 3.4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 CEH14992.1 - 6.7e-11 41.8 0.2 1.3e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CEH14992.1 - 6.1e-09 35.7 1.2 1.9e-08 34.0 0.1 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CEH14992.1 - 1.6e-05 24.6 0.1 7.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain PMT PF02366.13 CEH14995.1 - 1.4e-72 243.9 17.2 1.4e-72 243.9 11.9 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CEH14995.1 - 5.2e-27 94.6 1.7 1.4e-26 93.1 1.1 1.7 1 1 0 1 1 1 1 MIR domain Pribosyltran PF00156.22 CEH14996.1 - 2.4e-08 33.7 0.0 4.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Trans_reg_C PF00486.23 CEH14996.1 - 0.092 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal SNARE PF05739.14 CEH14997.1 - 8.4e-06 25.3 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 SNARE domain G0-G1_switch_2 PF15103.1 CEH14997.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 NAC PF01849.13 CEH14998.1 - 1.1e-19 69.6 0.0 2.3e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 CEH14998.1 - 0.0017 18.1 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Ribosomal_L6e PF01159.14 CEH14998.1 - 0.23 11.7 1.5 0.44 10.7 1.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L6e Ribosomal_L2_C PF03947.13 CEH14999.1 - 4e-26 91.3 0.2 1e-14 54.4 0.0 2.5 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CEH14999.1 - 8e-26 89.8 0.4 1.5e-25 88.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WD40 PF00400.27 CEH15000.1 - 3e-49 163.2 2.7 1.6e-09 37.3 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.7 CEH15000.1 - 5.8e-42 143.2 1.5 5.8e-42 143.2 1.0 3.6 2 2 0 2 2 2 1 Striatin family AA_kinase PF00696.23 CEH15001.1 - 1.8e-33 116.0 0.1 1e-31 110.3 0.1 2.7 1 1 0 1 1 1 1 Amino acid kinase family Choline_transpo PF04515.7 CEH15001.1 - 4.7e-26 91.3 12.6 5.6e-16 58.2 0.1 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter ACT PF01842.20 CEH15001.1 - 1.9e-10 40.0 0.1 5.1e-05 22.6 0.0 3.0 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 CEH15001.1 - 3.3e-10 39.3 1.1 9.8e-07 28.2 0.2 2.7 2 0 0 2 2 2 2 ACT domain Dus PF01207.12 CEH15002.1 - 8.3e-44 149.6 0.0 1.6e-41 142.1 0.0 2.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Atg8 PF02991.11 CEH15003.1 - 7.4e-52 173.6 0.1 8.7e-52 173.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CEH15003.1 - 4.4e-07 29.9 0.0 5.4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Alg6_Alg8 PF03155.10 CEH15005.1 - 1.2e-105 354.0 20.4 1.7e-72 244.7 6.7 3.0 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family Rad51 PF08423.6 CEH15006.1 - 2.2e-08 33.3 0.1 1.2e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CEH15006.1 - 1.6e-06 27.6 0.0 3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CEH15006.1 - 0.0026 16.8 0.2 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_19 PF13245.1 CEH15006.1 - 0.0053 16.4 0.2 0.014 15.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain GTSE1_N PF15259.1 CEH15006.1 - 0.0082 16.0 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 G-2 and S-phase expressed 1 DUF3744 PF12558.3 CEH15006.1 - 0.04 14.3 0.1 0.087 13.2 0.1 1.5 1 0 0 1 1 1 0 ATP-binding cassette cobalt transporter KaiC PF06745.8 CEH15006.1 - 0.053 12.6 0.1 0.094 11.8 0.1 1.3 1 0 0 1 1 1 0 KaiC Ligase_CoA PF00549.14 CEH15008.1 - 3.5e-09 36.4 0.0 8.4e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase SpoIIE PF07228.7 CEH15008.1 - 2.9e-07 30.3 0.0 0.00075 19.2 0.0 2.8 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) AF-4 PF05110.8 CEH15008.1 - 9.5 3.9 16.8 18 2.9 11.7 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SNARE_assoc PF09335.6 CEH15009.1 - 9.9e-13 48.3 5.5 1.5e-12 47.8 2.5 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4271 PF14093.1 CEH15009.1 - 0.0002 21.0 1.4 0.00035 20.3 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) DSPc PF00782.15 CEH15011.1 - 2.8e-20 72.2 0.0 3.5e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RhoGAP PF00620.22 CEH15012.1 - 8.7e-37 126.0 0.0 1.6e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 CEH15012.1 - 2e-14 53.7 0.0 2.9e-13 49.9 0.0 2.5 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 CEH15012.1 - 5.3e-11 42.5 0.0 1.5e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 RasGEF N-terminal motif PH PF00169.24 CEH15012.1 - 4.5e-05 23.5 0.0 0.26 11.5 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 CEH15012.1 - 0.034 14.3 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Grp1_Fun34_YaaH PF01184.14 CEH15013.1 - 2.2e-20 72.8 20.1 2.7e-20 72.5 13.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family OsmC PF02566.14 CEH15014.1 - 1.1e-16 60.7 0.0 1.7e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein PYNP_C PF07831.8 CEH15014.1 - 0.071 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain R3H PF01424.17 CEH15015.1 - 8.2e-13 47.8 0.1 1.4e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 CEH15015.1 - 2.7e-10 40.0 0.0 5.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEH15015.1 - 1.5e-07 30.9 0.1 3.4e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH15015.1 - 2e-05 24.3 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OPT PF03169.10 CEH15016.1 - 1e-167 559.3 52.8 1.2e-167 559.1 36.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein IDO PF01231.13 CEH15018.1 - 2.2e-131 438.1 0.0 2.7e-131 437.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PBP PF01161.15 CEH15019.1 - 6.1e-11 42.3 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Not1 PF04054.10 CEH15020.1 - 6.1e-98 328.1 0.0 1.5e-97 326.8 0.0 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CEH15020.1 - 2.8e-52 176.3 0.8 1.3e-51 174.1 0.5 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Med15 PF09606.5 CEH15020.1 - 0.018 13.2 66.8 0.031 12.5 46.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Tht1 PF04163.7 CEH15021.1 - 6.4e-10 38.0 0.1 1.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein AA_permease_2 PF13520.1 CEH15022.1 - 1.1e-47 162.6 50.1 1.4e-47 162.2 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEH15022.1 - 7.7e-27 93.7 46.7 1e-26 93.3 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease Sec7 PF01369.15 CEH15023.1 - 5.7e-60 202.2 0.0 9.8e-60 201.4 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CEH15023.1 - 1.7e-13 50.3 0.6 3.7e-10 39.4 0.1 3.1 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal PDEase_II PF02112.10 CEH15024.1 - 2.1e-39 135.4 0.0 3.9e-39 134.5 0.0 1.4 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 CEH15024.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Peptidase_M13_N PF05649.8 CEH15025.1 - 5.5e-88 295.6 0.0 7.1e-88 295.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 CEH15025.1 - 4e-53 179.6 0.0 6.6e-53 178.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 WD40 PF00400.27 CEH15026.1 - 1.3e-13 50.2 1.6 0.018 14.9 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF3639 PF12341.3 CEH15026.1 - 0.0039 17.1 0.7 0.0039 17.1 0.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) ALG3 PF05208.8 CEH15027.1 - 9.1e-105 350.9 11.3 1.5e-104 350.2 7.8 1.3 1 1 0 1 1 1 1 ALG3 protein DUF2512 PF10710.4 CEH15027.1 - 0.086 12.3 2.0 0.29 10.6 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) Hid1 PF12722.2 CEH15028.1 - 1.3e-97 327.5 0.0 1.3e-86 291.2 0.0 3.7 2 2 1 3 3 3 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 CEH15028.1 - 9.5e-37 126.4 0.0 6.1e-33 113.8 0.0 2.3 2 0 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein CDC45 PF02724.9 CEH15028.1 - 0.3 9.0 5.7 0.54 8.2 3.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 CEH15028.1 - 3.3 5.3 10.4 4.9 4.7 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.7 CEH15028.1 - 7.8 4.2 14.0 12 3.6 9.7 1.2 1 0 0 1 1 1 0 Nop14-like family SGL PF08450.7 CEH15029.1 - 0.00039 19.8 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region TrkH PF02386.11 CEH15031.1 - 6.9e-94 314.3 16.2 2e-92 309.5 4.6 2.1 2 0 0 2 2 2 2 Cation transport protein zf-RING_2 PF13639.1 CEH15032.1 - 1.9e-05 24.3 3.9 0.00035 20.3 1.2 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEH15032.1 - 0.00085 18.9 1.3 0.00085 18.9 0.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH15032.1 - 0.0019 18.1 6.2 0.0048 16.8 1.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH15032.1 - 0.011 15.4 1.6 0.011 15.4 1.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Tmpp129 PF10272.4 CEH15032.1 - 0.14 10.8 1.6 0.21 10.2 1.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-C3HC4_4 PF15227.1 CEH15032.1 - 5.4 6.9 6.6 5.5 6.9 2.6 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING COesterase PF00135.23 CEH15033.1 - 2.7e-99 333.3 0.0 3.3e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CEH15033.1 - 2.5e-05 23.9 0.7 0.0001 21.9 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold RNA_pol_Rpb1_5 PF04998.12 CEH15036.1 - 1.4e-96 323.0 0.3 2.3e-96 322.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CEH15036.1 - 2.5e-82 276.8 0.0 3.8e-82 276.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CEH15036.1 - 2.3e-65 219.5 0.0 4.4e-65 218.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CEH15036.1 - 8.7e-37 126.2 0.0 2.4e-36 124.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CEH15036.1 - 3.1e-30 104.0 0.0 7.5e-30 102.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 CEH15036.1 - 0.0033 16.8 0.2 0.0083 15.5 0.1 1.6 1 0 0 1 1 1 1 InsA N-terminal domain Baculo_ME53 PF06061.6 CEH15036.1 - 0.048 12.6 0.1 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 NDUF_B12 PF08122.7 CEH15037.1 - 0.066 12.9 3.9 0.4 10.4 0.6 2.6 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Albumin_I PF08027.6 CEH15037.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Albumin I TcdA_TcdB_pore PF12920.2 CEH15037.1 - 0.16 9.8 2.2 0.21 9.4 1.5 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Claudin_3 PF06653.6 CEH15037.1 - 0.53 9.9 3.7 0.5 10.0 1.4 1.5 1 1 1 2 2 2 0 Tight junction protein, Claudin-like WD40 PF00400.27 CEH15038.1 - 6.5e-25 86.0 16.2 1.5e-06 27.8 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat RCC1_2 PF13540.1 CEH15038.1 - 0.43 10.2 2.8 2.5 7.8 0.2 3.2 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Endonuclease_NS PF01223.18 CEH15039.1 - 2.2e-50 171.1 0.0 3.6e-50 170.4 0.0 1.3 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease UPF0121 PF03661.8 CEH15041.1 - 3.1e-20 72.4 4.7 5.3e-20 71.6 3.2 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) IPPT PF01715.12 CEH15042.1 - 6.8e-47 159.6 1.1 1.9e-23 82.7 0.3 3.3 2 1 0 2 2 2 2 IPP transferase Methyltransf_26 PF13659.1 CEH15042.1 - 7.2e-12 45.3 0.0 4.3e-11 42.8 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain UPF0020 PF01170.13 CEH15042.1 - 2.2e-09 37.1 0.1 0.001 18.6 0.1 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 AAA_17 PF13207.1 CEH15042.1 - 0.00066 20.4 0.0 0.0023 18.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEH15042.1 - 0.00076 19.3 0.1 0.79 9.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 CEH15042.1 - 0.0051 16.0 0.1 0.0094 15.1 0.1 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_18 PF13238.1 CEH15042.1 - 0.0061 16.8 0.2 0.19 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CEH15042.1 - 0.0078 15.9 0.8 0.049 13.3 0.3 2.5 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 CEH15042.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 CEH15042.1 - 0.016 15.3 0.1 0.062 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CEH15042.1 - 0.027 13.8 0.1 0.092 12.1 0.1 1.9 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 CEH15042.1 - 0.042 13.6 0.7 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 IPT PF01745.11 CEH15042.1 - 0.06 12.5 1.8 0.15 11.2 0.1 2.5 2 1 0 2 2 2 0 Isopentenyl transferase MobB PF03205.9 CEH15042.1 - 0.19 11.4 0.1 0.46 10.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CEH15042.1 - 0.22 11.7 0.0 0.47 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 CEH15042.1 - 0.24 10.6 0.2 0.62 9.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 dsrm PF00035.20 CEH15043.1 - 3.2e-05 24.3 0.0 5.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 CEH15043.1 - 0.006 17.0 0.2 0.015 15.7 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain SPT16 PF08644.6 CEH15044.1 - 1.7e-55 187.0 0.1 4.1e-55 185.8 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 CEH15044.1 - 2.1e-42 144.4 0.3 5.2e-42 143.1 0.2 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CEH15044.1 - 3.6e-21 75.7 0.0 6.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 CEH15044.1 - 1.1e-19 70.1 0.1 6e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like BTB PF00651.26 CEH15045.1 - 2e-10 40.6 0.0 0.0001 22.2 0.0 3.3 3 0 0 3 3 3 3 BTB/POZ domain FAD_binding_8 PF08022.7 CEH15046.1 - 4.3e-19 68.3 0.0 1.1e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CEH15046.1 - 4.8e-12 46.0 0.0 1.5e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CEH15046.1 - 1.2e-10 41.5 7.9 1.2e-10 41.5 5.4 1.9 1 1 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_6 PF13405.1 CEH15046.1 - 0.00022 20.8 0.3 0.00077 19.1 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 CEH15046.1 - 0.00034 19.7 0.2 0.00091 18.3 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CEH15046.1 - 0.00057 19.9 0.6 0.0021 18.1 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CEH15046.1 - 0.0022 17.5 0.2 0.0075 15.8 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair FAD_binding_6 PF00970.19 CEH15046.1 - 0.0038 17.3 0.0 0.0087 16.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain EF-hand_5 PF13202.1 CEH15046.1 - 0.0043 16.3 0.3 0.012 14.8 0.1 1.9 2 0 0 2 2 2 1 EF hand Hep_59 PF07052.6 CEH15047.1 - 3.8e-24 85.0 0.4 3.8e-24 85.0 0.3 2.6 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 AMP-binding PF00501.23 CEH15048.1 - 4.1e-73 246.1 0.0 5.8e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEH15048.1 - 5.7e-12 46.4 2.5 4.1e-11 43.6 0.1 3.1 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 CEH15050.1 - 4.7e-71 238.9 0.0 5.6e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15050.1 - 7.6e-31 107.1 0.0 9.5e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH15050.1 - 1.8e-07 30.4 0.0 2.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEH15050.1 - 0.0011 18.0 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CEH15050.1 - 0.0035 16.7 0.1 0.0064 15.8 0.1 1.5 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 CEH15050.1 - 0.0055 16.4 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family 5_nucleotid PF05761.9 CEH15050.1 - 0.027 13.0 0.1 0.039 12.4 0.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family Mtr2 PF10429.4 CEH15052.1 - 5.1e-07 29.5 0.0 4e-06 26.6 0.0 2.0 1 1 1 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.15 CEH15052.1 - 6.3e-07 29.7 0.0 3.1e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain AMP-binding PF00501.23 CEH15053.1 - 1.7e-69 234.2 0.0 2.2e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1212 PF06738.7 CEH15056.1 - 3.6e-34 117.9 13.5 5.9e-33 113.9 0.5 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CEH15056.1 - 6.5e-18 64.9 11.6 6.5e-18 64.9 8.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) EcsB PF05975.7 CEH15056.1 - 0.16 10.3 3.5 1.9 6.9 0.2 2.3 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Mit_ribos_Mrp51 PF11709.3 CEH15057.1 - 2.5e-12 46.6 0.0 1.2e-11 44.4 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit QCR10 PF09796.4 CEH15058.1 - 3.3e-23 81.1 0.1 4.3e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 CEH15058.1 - 0.054 13.1 2.0 0.1 12.3 1.4 1.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein HOOK PF05622.7 CEH15059.1 - 3.5e-51 173.9 45.3 3.5e-51 173.9 31.4 3.0 1 1 1 2 2 2 1 HOOK protein NYD-SP28_assoc PF14775.1 CEH15059.1 - 0.18 11.5 5.2 0.087 12.5 0.7 2.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain Adaptin_N PF01602.15 CEH15060.1 - 2.8e-149 497.8 1.4 3.6e-149 497.4 0.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CEH15060.1 - 4.4e-26 91.8 0.1 1.3e-22 80.4 0.0 3.6 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CEH15060.1 - 4.2e-16 58.9 7.3 6.7e-06 26.2 0.0 5.6 2 1 3 5 5 5 5 HEAT repeats HEAT PF02985.17 CEH15060.1 - 6.6e-10 38.2 5.3 0.0085 16.0 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 CEH15060.1 - 3.4e-06 27.3 4.6 0.0079 16.6 0.1 6.5 5 2 2 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 CEH15060.1 - 5e-05 22.7 0.1 0.11 11.8 0.0 3.0 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.18 CEH15060.1 - 0.003 17.3 0.8 0.95 9.3 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 CEH15060.1 - 0.006 15.6 0.2 0.1 11.5 0.0 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Ras PF00071.17 CEH15061.1 - 6.1e-63 211.0 0.9 7.2e-63 210.7 0.6 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH15061.1 - 2.1e-20 73.3 0.0 3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH15061.1 - 1.8e-17 63.1 0.1 2.2e-17 62.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEH15061.1 - 6.8e-07 28.9 0.3 1.9e-06 27.4 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEH15061.1 - 2.4e-06 26.8 0.1 2.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CEH15061.1 - 6.5e-06 25.4 0.0 1.1e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CEH15061.1 - 0.00043 20.2 0.0 0.00073 19.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CEH15061.1 - 0.0017 18.4 0.0 0.0033 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 CEH15061.1 - 0.0039 16.4 0.1 0.031 13.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_5 PF07728.9 CEH15061.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CEH15061.1 - 0.0068 16.6 0.1 0.38 10.9 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CEH15061.1 - 0.026 14.8 0.0 0.038 14.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 CEH15061.1 - 0.03 14.3 0.1 0.062 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CEH15061.1 - 0.049 13.1 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CEH15061.1 - 0.1 11.7 0.1 0.6 9.2 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Na_H_Exchanger PF00999.16 CEH15062.1 - 3.7e-61 206.7 38.3 4.7e-61 206.4 26.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Dabb PF07876.7 CEH15064.1 - 1.4e-14 54.2 0.0 1.6e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ran_BP1 PF00638.13 CEH15065.1 - 1.8e-11 44.1 0.1 4.3e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 RanBP1 domain PAPS_reduct PF01507.14 CEH15066.1 - 3.2e-21 75.9 0.0 1e-16 61.2 0.0 2.6 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Pkinase PF00069.20 CEH15067.1 - 6.4e-71 238.5 0.0 1e-70 237.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Abhydrolase_3 PF07859.8 CEH15067.1 - 6.4e-45 153.3 0.1 2.2e-44 151.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pkinase_Tyr PF07714.12 CEH15067.1 - 3.6e-33 114.7 0.0 6.1e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2424 PF10340.4 CEH15067.1 - 9.6e-11 40.9 0.0 2.9e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) YrbL-PhoP_reg PF10707.4 CEH15067.1 - 7.7e-06 25.3 0.0 1.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CEH15067.1 - 0.0011 18.1 0.0 0.0028 16.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CEH15067.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 CEH15067.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family SOR_SNZ PF01680.12 CEH15069.1 - 8.5e-114 378.3 4.7 1.2e-113 377.8 3.3 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 CEH15069.1 - 1.6e-07 30.6 4.5 3.3e-05 23.0 0.1 2.6 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 CEH15069.1 - 0.0082 15.4 0.3 0.22 10.7 0.0 2.5 3 0 0 3 3 3 1 Histidine biosynthesis protein NanE PF04131.9 CEH15069.1 - 0.01 14.7 0.4 0.15 10.9 0.0 2.6 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.12 CEH15069.1 - 0.017 13.9 0.4 4.1 6.1 0.1 2.3 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) IGPS PF00218.16 CEH15069.1 - 0.02 13.9 0.1 0.13 11.3 0.0 2.1 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Trp_syntA PF00290.15 CEH15069.1 - 0.059 11.8 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Abhydrolase_5 PF12695.2 CEH15070.1 - 1.6e-07 31.1 0.5 3.6e-07 30.0 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH15070.1 - 3.1e-05 23.9 0.2 4.2e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CEH15070.1 - 0.0039 16.7 0.1 0.0068 16.0 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 CEH15070.1 - 0.004 16.7 0.0 0.0068 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 CEH15070.1 - 0.023 13.9 0.0 0.056 12.7 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.15 CEH15070.1 - 0.059 12.7 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 CEH15070.1 - 0.18 11.1 0.1 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) UCR_TM PF02921.9 CEH15071.1 - 1.6e-18 66.6 2.5 3.7e-18 65.5 1.7 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 CEH15071.1 - 1.1e-16 60.1 0.1 1.7e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF1772 PF08592.6 CEH15072.1 - 1.3e-11 44.3 1.8 1.7e-11 44.0 0.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF423 PF04241.10 CEH15074.1 - 3.7e-25 87.6 5.1 5.1e-25 87.2 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF2231 PF09990.4 CEH15074.1 - 0.33 11.3 5.8 0.77 10.1 1.9 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF202 PF02656.10 CEH15074.1 - 2.1 8.6 7.6 98 3.2 5.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Ion_trans PF00520.26 CEH15075.1 - 1.2e-101 338.0 62.4 2.5e-36 124.8 1.8 4.7 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.7 CEH15075.1 - 0.0019 16.6 61.2 0.018 13.5 1.5 8.0 7 2 2 9 9 9 7 Polycystin cation channel DUF4100 PF13352.1 CEH15075.1 - 1 8.7 0.0 1.9 7.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) Arf PF00025.16 CEH15076.1 - 6.6e-76 253.4 0.0 7.6e-76 253.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CEH15076.1 - 6.9e-13 48.2 0.0 7.6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CEH15076.1 - 3e-11 42.8 0.0 3.8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CEH15076.1 - 9.6e-11 40.9 1.0 8.1e-07 28.0 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CEH15076.1 - 7.1e-10 38.4 0.0 8.7e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CEH15076.1 - 1.7e-07 31.7 0.0 2.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CEH15076.1 - 0.00023 21.1 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CEH15076.1 - 0.0012 17.9 0.1 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CEH15076.1 - 0.039 13.3 0.0 0.29 10.5 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Cellulase PF00150.13 CEH15077.1 - 1.6e-12 47.2 0.0 4e-05 22.9 0.0 3.0 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) GMC_oxred_C PF05199.8 CEH15077.1 - 0.0025 18.1 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase zf-C3HC4_3 PF13920.1 CEH15078.1 - 1.3e-05 24.7 8.1 1.3e-05 24.7 5.6 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH15078.1 - 7.9 6.2 28.9 0.29 10.8 7.7 3.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 CEH15079.1 - 2.2e-42 144.4 0.8 3.7e-42 143.6 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH15079.1 - 6e-27 93.3 1.0 1.7e-26 91.8 0.2 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CEH15079.1 - 0.00025 20.7 0.2 0.00058 19.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CEH15079.1 - 0.00066 19.5 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CEH15079.1 - 0.0092 16.1 0.0 0.025 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 CEH15079.1 - 0.026 13.6 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 CEH15079.1 - 0.037 13.5 0.3 0.11 12.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain Dynactin PF12455.3 CEH15081.1 - 8.2e-70 234.8 0.1 8.2e-70 234.8 0.1 3.0 3 0 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 CEH15081.1 - 4.2e-19 68.0 0.1 6.8e-19 67.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF4418 PF14387.1 CEH15081.1 - 0.41 10.3 0.1 0.68 9.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) WD40_alt PF14077.1 CEH15081.1 - 5.1 6.8 9.0 14 5.3 0.1 3.8 4 0 0 4 4 4 0 Alternative WD40 repeat motif Far-17a_AIG1 PF04750.9 CEH15082.1 - 0.1 11.7 15.4 0.72 8.9 10.5 2.4 1 1 0 1 1 1 0 FAR-17a/AIG1-like protein MFS_1 PF07690.11 CEH15083.1 - 5.8e-29 100.9 23.2 5.8e-29 100.9 16.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily SE PF08491.5 CEH15084.1 - 7.5e-95 316.8 0.0 1.2e-94 316.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 CEH15084.1 - 4.2e-11 42.4 0.1 1e-10 41.2 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEH15084.1 - 2.1e-10 40.0 1.2 1.2e-06 27.6 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CEH15084.1 - 0.00091 17.9 0.8 0.31 9.6 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.17 CEH15084.1 - 0.0012 17.7 0.3 0.025 13.4 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 CEH15084.1 - 0.0017 17.5 1.4 0.0029 16.7 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CEH15084.1 - 0.0019 18.0 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CEH15084.1 - 0.0025 16.9 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CEH15084.1 - 0.0029 17.6 2.6 0.0071 16.3 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CEH15084.1 - 0.0076 16.6 0.5 0.017 15.5 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CEH15084.1 - 0.014 13.9 0.0 0.02 13.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 CEH15084.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SUZ-C PF12901.2 CEH15084.1 - 0.12 12.0 1.4 0.33 10.6 0.9 1.8 1 0 0 1 1 1 0 SUZ-C motif FAD_binding_2 PF00890.19 CEH15084.1 - 0.13 11.1 3.4 0.099 11.4 1.3 1.5 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 CEH15084.1 - 0.15 10.9 1.5 0.82 8.5 0.2 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein GDI PF00996.13 CEH15084.1 - 0.23 9.7 0.0 0.35 9.1 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor BatA PF07584.6 CEH15084.1 - 2 8.6 6.8 57 4.0 0.2 3.7 3 1 0 3 3 3 0 Aerotolerance regulator N-terminal Cyclase PF04199.8 CEH15085.1 - 2.3e-18 66.4 0.0 5.2e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Putative cyclase RabGAP-TBC PF00566.13 CEH15086.1 - 5.8e-34 117.4 0.0 1.2e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 CEH15087.1 - 1.8e-69 233.7 0.0 2.6e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15087.1 - 1.2e-49 168.7 0.0 1.7e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH15087.1 - 3.4e-06 26.2 0.0 1.7e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like UBA PF00627.26 CEH15088.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Pil1 PF13805.1 CEH15089.1 - 5.9e-24 84.6 0.6 1.4e-23 83.4 0.4 1.5 1 0 0 1 1 1 1 Eisosome component PIL1 GAS PF13851.1 CEH15089.1 - 0.027 13.6 5.5 0.042 13.0 3.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3418 PF11898.3 CEH15089.1 - 0.031 12.6 0.8 0.045 12.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) DUF2730 PF10805.3 CEH15089.1 - 0.037 13.7 0.9 0.068 12.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Spc24 PF08286.6 CEH15089.1 - 0.039 13.6 2.8 0.1 12.3 1.9 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 CENP-Q PF13094.1 CEH15089.1 - 0.044 13.8 4.4 0.12 12.3 3.1 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Microtub_assoc PF07989.6 CEH15089.1 - 0.96 9.3 4.3 2 8.3 3.0 1.6 1 0 0 1 1 1 0 Microtubule associated Mnd1 PF03962.10 CEH15089.1 - 2.2 7.8 6.1 1.6 8.3 3.0 1.6 2 0 0 2 2 2 0 Mnd1 family DUF3617 PF12276.3 CEH15091.1 - 0.0027 17.1 1.4 0.004 16.6 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3617) SNARE_assoc PF09335.6 CEH15094.1 - 1.1e-12 48.2 4.6 1.1e-12 48.2 3.2 2.7 2 1 2 4 4 4 1 SNARE associated Golgi protein MAP65_ASE1 PF03999.7 CEH15095.1 - 0.12 10.9 2.1 0.13 10.8 1.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ORC6 PF05460.8 CEH15095.1 - 2.8 6.9 7.3 3 6.8 5.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Myb_DNA-bind_6 PF13921.1 CEH15098.1 - 0.0008 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 CEH15098.1 - 0.3 10.6 2.1 0.94 9.0 1.5 1.8 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain Myb_DNA-bind_6 PF13921.1 CEH15100.1 - 0.00011 22.2 0.2 0.00021 21.2 0.1 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEH15100.1 - 0.012 15.6 1.8 0.14 12.2 1.3 2.1 1 1 0 1 1 1 0 Myb-like DNA-binding domain Rap1_C PF11626.3 CEH15100.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 CEH15102.1 - 0.0003 20.7 0.0 0.00072 19.5 0.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH15102.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain CybS PF05328.7 CEH15104.1 - 1.3e-41 141.3 0.0 1.6e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 CybS Mito_carr PF00153.22 CEH15105.1 - 0.0051 16.4 0.0 0.43 10.3 0.0 3.0 3 0 0 3 3 3 1 Mitochondrial carrier protein Rod_cone_degen PF15201.1 CEH15105.1 - 0.022 14.5 1.5 8.6 6.2 0.1 3.2 2 0 0 2 2 2 0 Progressive rod-cone degeneration DUF938 PF06080.7 CEH15106.1 - 9.9e-33 113.3 1.5 7.5e-16 58.2 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF938) COX4 PF02936.9 CEH15107.1 - 2.6e-38 130.9 0.0 3.4e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV HMG_box_2 PF09011.5 CEH15107.1 - 0.12 12.7 5.5 0.39 11.1 0.0 2.9 2 1 1 3 3 3 0 HMG-box domain Pyr_redox_2 PF07992.9 CEH15108.1 - 1.2e-29 103.6 0.0 1.6e-29 103.2 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEH15108.1 - 4.4e-17 62.2 0.5 4.2e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEH15108.1 - 1.6e-07 31.5 0.0 0.0003 20.8 0.0 2.7 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH15108.1 - 5.1e-06 26.4 0.1 0.00035 20.5 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CEH15108.1 - 2e-05 23.8 0.4 0.00016 20.8 0.0 2.3 2 1 1 3 3 3 1 Thi4 family GIDA PF01134.17 CEH15108.1 - 2.6e-05 23.2 3.5 0.0051 15.7 0.0 3.4 3 1 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 CEH15108.1 - 5.7e-05 22.3 0.8 0.055 12.5 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase DAO PF01266.19 CEH15108.1 - 0.0002 20.3 1.3 0.018 13.9 0.0 3.0 1 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CEH15108.1 - 0.00023 21.3 0.1 0.031 14.5 0.0 2.9 2 2 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CEH15108.1 - 0.00027 21.0 0.4 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 CEH15108.1 - 0.0003 19.7 2.3 0.0068 15.2 0.1 2.4 2 1 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 CEH15108.1 - 0.0007 18.6 0.2 0.61 8.9 0.0 3.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 CEH15108.1 - 0.0015 17.2 0.2 0.045 12.3 0.0 2.6 2 1 1 3 3 3 1 Tryptophan halogenase FAD_binding_3 PF01494.14 CEH15108.1 - 0.0017 17.4 0.5 0.04 12.9 0.0 2.6 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.9 CEH15108.1 - 0.0047 15.4 0.1 0.027 12.9 0.0 2.2 3 0 0 3 3 3 1 HI0933-like protein F420_oxidored PF03807.12 CEH15108.1 - 0.018 15.4 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 CEH15108.1 - 0.04 13.2 0.0 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 CEH15108.1 - 0.043 13.5 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SH3BGR PF04908.10 CEH15109.1 - 2.3e-07 30.6 0.0 1e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein PCI PF01399.22 CEH15110.1 - 1.8e-09 37.8 0.6 6.3e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 PCI domain Aminotran_5 PF00266.14 CEH15111.1 - 2.6e-30 105.3 0.0 2.3e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V HAD_2 PF13419.1 CEH15112.1 - 5.9e-19 68.9 0.0 5.6e-14 52.7 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEH15112.1 - 8.1e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CEH15112.1 - 9.7e-05 22.8 0.0 0.00032 21.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HTH_1 PF00126.22 CEH15112.1 - 0.042 13.6 0.1 0.042 13.6 0.1 2.4 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family SUZ PF12752.2 CEH15113.1 - 1.5e-10 41.4 4.3 1.5e-10 41.4 3.0 4.7 4 0 0 4 4 4 1 SUZ domain UCH PF00443.24 CEH15114.1 - 8.6e-42 143.0 0.0 1.2e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEH15114.1 - 8.2e-14 51.7 0.0 4.5e-13 49.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase An_peroxidase PF03098.10 CEH15115.1 - 5.4e-73 246.1 0.0 1.1e-70 238.5 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 CEH15115.1 - 5e-11 41.7 0.0 9.9e-11 40.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 CEH15117.1 - 5.2e-78 262.4 37.2 6.6e-78 262.1 25.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEH15117.1 - 2.1e-18 65.9 32.9 4.8e-18 64.7 22.7 1.6 1 1 0 1 1 1 1 Amino acid permease HN PF00423.14 CEH15117.1 - 0.19 10.0 0.0 0.28 9.4 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase HEAT PF02985.17 CEH15119.1 - 4.3e-07 29.4 15.6 0.0073 16.3 0.0 7.4 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 CEH15119.1 - 1.9e-05 24.8 11.2 0.13 12.5 0.1 5.2 3 1 2 5 5 5 4 HEAT repeats Adaptin_N PF01602.15 CEH15119.1 - 0.0017 16.7 0.2 0.57 8.4 0.0 2.6 2 1 1 3 3 3 2 Adaptin N terminal region DAO PF01266.19 CEH15120.1 - 9e-41 139.9 2.3 1e-40 139.7 1.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEH15120.1 - 0.0057 16.6 0.9 0.029 14.3 0.2 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CEH15120.1 - 0.15 12.4 0.7 24 5.4 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DSBA PF01323.15 CEH15121.1 - 6.6e-32 110.6 0.1 7.5e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain CDC50 PF03381.10 CEH15122.1 - 2.1e-92 309.2 0.0 2.6e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family VMA21 PF09446.5 CEH15122.1 - 0.92 9.4 5.2 0.24 11.3 1.0 1.9 2 0 0 2 2 2 0 VMA21-like domain RabGAP-TBC PF00566.13 CEH15125.1 - 1.5e-19 70.3 0.0 9e-18 64.5 0.0 2.8 2 1 0 2 2 2 1 Rab-GTPase-TBC domain CDRN PF05174.7 CEH15125.1 - 1.5 8.3 4.3 31 4.1 0.7 2.9 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus Response_reg PF00072.19 CEH15126.1 - 2.7e-19 69.2 0.1 5e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 CEH15126.1 - 4.5e-16 58.5 0.0 8.2e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 CEH15126.1 - 1.3e-05 25.1 0.1 3.3e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 CEH15126.1 - 0.0061 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank PF00023.25 CEH15127.1 - 7.1e-13 47.6 0.3 1.3e-07 31.0 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CEH15127.1 - 1e-11 44.9 0.2 1.5e-05 25.3 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CEH15127.1 - 1.2e-11 44.7 0.0 4.4e-10 39.7 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEH15127.1 - 2e-09 37.4 0.5 1.1e-06 28.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH15127.1 - 1.4e-07 31.0 0.0 0.00022 21.1 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat FSH1 PF03959.8 CEH15128.1 - 1.3e-14 54.1 0.0 1.8e-13 50.4 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF4477 PF14780.1 CEH15128.1 - 0.0073 15.6 0.0 0.019 14.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4477) PigN PF04987.9 CEH15129.1 - 2.3e-89 300.0 7.9 2.7e-88 296.5 5.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CEH15129.1 - 4.3e-07 29.5 1.0 2.3e-05 23.8 0.2 2.5 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CEH15129.1 - 4.3e-05 22.8 0.1 7.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CEH15129.1 - 0.23 10.8 0.0 0.48 9.7 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily RNase_P_Rpp14 PF01900.14 CEH15130.1 - 3.5e-17 62.2 0.1 4.8e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family PSD1 PF07587.6 CEH15130.1 - 0.037 13.4 0.7 0.043 13.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) UPAR_LY6 PF00021.16 CEH15130.1 - 0.098 13.0 1.5 0.17 12.3 1.0 1.4 1 0 0 1 1 1 0 u-PAR/Ly-6 domain DUF399 PF04187.8 CEH15131.1 - 6.5e-15 55.2 0.0 0.00011 21.8 0.0 4.4 4 0 0 4 4 4 4 Protein of unknown function, DUF399 Ribosomal_60s PF00428.14 CEH15131.1 - 8.4 6.8 8.7 4.6 7.6 2.7 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein adh_short PF00106.20 CEH15132.1 - 3.2e-28 98.7 0.9 4.5e-28 98.2 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH15132.1 - 5.7e-14 52.4 0.1 7.4e-14 52.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH15132.1 - 5.1e-10 39.2 0.4 7.7e-10 38.7 0.2 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CEH15132.1 - 4.1e-05 23.2 1.1 8.9e-05 22.2 0.7 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CEH15132.1 - 0.002 17.6 0.3 0.0036 16.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEH15132.1 - 0.007 16.3 2.6 0.063 13.2 1.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CEH15132.1 - 0.0074 15.2 0.2 0.0097 14.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 CEH15132.1 - 0.0094 15.6 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CEH15132.1 - 0.047 13.1 0.4 0.096 12.1 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.14 CEH15132.1 - 0.094 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AA_permease_2 PF13520.1 CEH15133.1 - 4.9e-47 160.4 39.0 2.1e-43 148.4 21.0 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 CEH15133.1 - 9.8e-16 57.1 39.9 4.4e-15 54.9 22.3 3.0 2 1 0 2 2 2 2 Amino acid permease GWT1 PF06423.7 CEH15133.1 - 4 7.5 11.0 0.46 10.5 0.5 3.5 3 1 0 3 3 3 0 GWT1 SR-25 PF10500.4 CEH15134.1 - 0.0079 15.6 2.1 0.0094 15.4 1.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RF-1 PF00472.15 CEH15135.1 - 3.2e-36 123.5 6.0 7.2e-36 122.4 4.1 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CEH15135.1 - 1.2e-25 89.4 0.1 2.6e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 PCRF domain R_equi_Vir PF05526.6 CEH15135.1 - 0.25 10.9 1.3 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein CMS1 PF14617.1 CEH15136.1 - 0.034 13.2 0.3 0.034 13.2 0.2 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DNA_topoisoIV PF00521.15 CEH15137.1 - 4.1e-128 427.8 0.0 7.2e-128 427.0 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CEH15137.1 - 2.4e-33 114.7 2.5 4.8e-33 113.7 1.8 1.5 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CEH15137.1 - 2.5e-14 53.0 0.2 2.7e-13 49.7 0.0 2.6 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 CEH15137.1 - 7.9e-09 35.2 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Na_Ca_ex PF01699.19 CEH15138.1 - 1.4e-08 34.4 23.9 1.6e-06 27.7 5.0 3.1 2 1 0 2 2 2 2 Sodium/calcium exchanger protein ATG_C PF09333.6 CEH15139.1 - 3e-21 75.3 0.3 1.9e-20 72.7 0.0 2.5 2 0 0 2 2 2 1 ATG C terminal domain Chorein_N PF12624.2 CEH15139.1 - 1e-05 25.0 0.0 2.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Ribosomal_S13_N PF08069.7 CEH15139.1 - 0.011 15.5 0.0 0.59 10.0 0.0 2.7 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain ATG2_CAD PF13329.1 CEH15139.1 - 0.011 15.3 0.0 0.083 12.4 0.0 2.4 2 0 0 2 2 2 0 Autophagy-related protein 2 CAD motif GlutR_dimer PF00745.15 CEH15139.1 - 0.039 13.9 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain EF-hand_4 PF12763.2 CEH15140.1 - 1.7e-33 114.4 0.0 6.1e-13 48.3 0.0 3.3 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 CEH15140.1 - 2.5e-08 33.5 0.0 6.9e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 CEH15140.1 - 1e-07 31.9 0.0 0.023 14.8 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair UBA_3 PF09288.5 CEH15140.1 - 0.00026 20.5 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain EF-hand_1 PF00036.27 CEH15140.1 - 0.00046 19.2 0.0 4.9 6.6 0.0 4.2 4 0 0 4 4 4 0 EF hand ERM PF00769.14 CEH15140.1 - 0.00096 18.7 11.2 0.002 17.7 7.8 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family TMCO5 PF14992.1 CEH15140.1 - 0.0017 17.5 10.0 0.0026 16.9 6.9 1.2 1 0 0 1 1 1 1 TMCO5 family EF-hand_8 PF13833.1 CEH15140.1 - 0.0042 16.6 0.0 4.7 6.8 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain pair CENP-Q PF13094.1 CEH15140.1 - 0.0055 16.7 6.0 0.0055 16.7 4.2 2.3 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 CEH15140.1 - 0.012 14.7 10.0 0.079 12.1 1.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 CEH15140.1 - 0.016 15.0 22.2 0.35 10.6 6.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cast PF10174.4 CEH15140.1 - 0.031 12.3 18.6 0.042 11.9 12.9 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone EF-hand_6 PF13405.1 CEH15140.1 - 0.099 12.5 3.8 26 5.0 0.0 4.8 6 0 0 6 6 4 0 EF-hand domain V_ATPase_I PF01496.14 CEH15140.1 - 0.13 10.0 10.8 0.1 10.4 6.4 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CEH15140.1 - 0.16 11.5 20.0 0.025 14.1 9.4 2.1 1 1 1 2 2 2 0 IncA protein TSC22 PF01166.13 CEH15140.1 - 0.19 11.7 1.6 0.52 10.3 1.1 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family UBA_2 PF08587.6 CEH15140.1 - 0.22 11.7 0.0 0.52 10.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) APG6 PF04111.7 CEH15140.1 - 0.52 9.2 13.7 0.87 8.5 9.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CALCOCO1 PF07888.6 CEH15140.1 - 0.58 8.3 14.0 0.94 7.6 9.7 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_13 PF13166.1 CEH15140.1 - 0.59 8.5 8.5 0.87 7.9 5.9 1.1 1 0 0 1 1 1 0 AAA domain Phlebovirus_NSM PF07246.6 CEH15140.1 - 0.74 8.9 6.5 1.2 8.2 4.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M GAS PF13851.1 CEH15140.1 - 0.75 8.9 17.2 0.59 9.2 4.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EzrA PF06160.7 CEH15140.1 - 0.78 7.8 11.2 0.38 8.8 6.0 1.5 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Macoilin PF09726.4 CEH15140.1 - 0.93 7.7 10.4 1.4 7.0 7.2 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF812 PF05667.6 CEH15140.1 - 1.2 7.5 12.4 2 6.8 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF972 PF06156.8 CEH15140.1 - 2.1 8.7 13.3 0.17 12.2 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2353 PF09789.4 CEH15140.1 - 2.2 7.4 16.1 2.8 7.1 2.7 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF1319 PF07028.6 CEH15140.1 - 2.5 8.3 9.3 1.1e+02 3.0 6.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) bZIP_2 PF07716.10 CEH15140.1 - 3.6 7.4 13.4 0.14 12.0 3.7 2.6 2 1 1 3 3 3 0 Basic region leucine zipper CENP-F_leu_zip PF10473.4 CEH15140.1 - 4.3 7.1 23.9 4.3 7.2 15.1 2.0 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 CEH15140.1 - 7.7 5.9 17.9 9.2 5.6 8.5 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Myosin_tail_1 PF01576.14 CEH15142.1 - 0.011 13.5 17.0 0.13 9.9 11.8 2.2 1 1 0 1 1 1 0 Myosin tail ADIP PF11559.3 CEH15142.1 - 0.17 11.7 13.5 0.081 12.8 2.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 CEH15142.1 - 0.18 11.5 6.6 0.17 11.6 0.2 2.6 1 1 2 3 3 3 0 Laminin Domain II DUF4085 PF13315.1 CEH15142.1 - 0.18 11.1 2.5 0.47 9.8 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) Pox_A_type_inc PF04508.7 CEH15142.1 - 0.19 11.5 4.5 1.4 8.8 0.6 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat MscS_porin PF12795.2 CEH15142.1 - 0.4 9.9 11.9 0.93 8.7 5.2 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF4200 PF13863.1 CEH15142.1 - 2 8.4 13.2 3.3 7.6 5.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 CEH15142.1 - 2.6 6.4 10.4 4.9 5.4 7.2 1.3 1 1 0 1 1 1 0 AAA domain IncA PF04156.9 CEH15142.1 - 3.5 7.1 13.8 19 4.7 9.8 2.0 1 1 0 1 1 1 0 IncA protein zf-RING_2 PF13639.1 CEH15144.1 - 4.7e-05 23.1 3.4 7.3e-05 22.5 2.4 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 CEH15144.1 - 0.002 17.8 1.8 0.002 17.8 1.3 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 CEH15144.1 - 0.0077 15.9 1.9 0.016 14.8 1.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 CEH15144.1 - 0.037 13.7 6.3 0.15 11.7 4.4 1.9 1 1 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 CEH15144.1 - 0.29 11.1 2.1 0.51 10.3 1.4 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain C1_2 PF03107.11 CEH15144.1 - 0.37 10.9 6.1 0.57 10.3 4.3 1.3 1 0 0 1 1 1 0 C1 domain zf-HC5HC2H PF13771.1 CEH15144.1 - 0.64 10.1 3.7 1.5 9.0 2.6 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-MIZ PF02891.15 CEH15144.1 - 1.7 8.2 5.0 1.2 8.6 0.2 2.6 2 1 1 3 3 3 0 MIZ/SP-RING zinc finger zf-C3HC4_3 PF13920.1 CEH15144.1 - 2.1 8.0 5.5 4.5 7.0 3.8 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4449 PF14613.1 CEH15145.1 - 0.00026 20.9 0.5 0.00026 20.9 0.4 3.8 3 1 0 4 4 4 1 Protein of unknown function (DUF4449) Pkinase PF00069.20 CEH15148.1 - 5.6e-64 215.8 0.0 6.3e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15148.1 - 7.3e-33 113.7 0.0 9.2e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH15148.1 - 1e-06 27.9 0.0 1.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like PUF PF00806.14 CEH15149.1 - 3.3e-06 26.2 0.0 0.0061 15.9 0.0 3.0 2 0 0 2 2 2 2 Pumilio-family RNA binding repeat DUF4407 PF14362.1 CEH15150.1 - 0.12 11.2 0.7 0.18 10.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gon7 PF08738.5 CEH15150.1 - 0.18 11.8 6.4 0.2 11.6 3.1 2.1 2 1 0 2 2 2 0 Gon7 family Ribosomal_60s PF00428.14 CEH15150.1 - 3.7 8.0 11.0 0.58 10.5 3.3 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein Macoilin PF09726.4 CEH15150.1 - 4.9 5.3 10.1 7.9 4.6 7.0 1.4 1 1 0 1 1 1 0 Transmembrane protein DUF2781 PF10914.3 CEH15152.1 - 3.6e-20 72.2 6.4 3.5e-13 49.5 2.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2781) CFC PF09443.5 CEH15152.1 - 0.14 11.7 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) CDRN PF05174.7 CEH15153.1 - 0.11 12.0 0.3 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus zf-RING_2 PF13639.1 CEH15154.1 - 2.2e-11 43.4 1.2 3.2e-11 42.8 0.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEH15154.1 - 1.5e-07 31.4 0.2 2.2e-07 30.8 0.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CEH15154.1 - 4.2e-07 29.5 0.4 6.5e-07 28.9 0.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH15154.1 - 7.3e-07 29.1 1.0 1.1e-06 28.5 0.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH15154.1 - 1.3e-06 28.0 0.3 1.9e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CEH15154.1 - 1.7e-06 27.5 0.8 2.7e-06 26.9 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CEH15154.1 - 5e-05 23.0 0.1 7.5e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CEH15154.1 - 0.087 12.8 0.7 0.17 11.9 0.5 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 CEH15154.1 - 0.36 10.8 4.2 7.7 6.5 2.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain HpcH_HpaI PF03328.9 CEH15156.1 - 7.9e-15 54.3 0.0 1.3e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 CEH15156.1 - 2.5e-08 33.1 0.0 4.2e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold Striatin PF08232.7 CEH15158.1 - 0.0023 18.2 5.4 0.0026 18.0 3.7 1.1 1 0 0 1 1 1 1 Striatin family ADIP PF11559.3 CEH15158.1 - 0.012 15.4 8.1 0.015 15.1 5.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Shugoshin_N PF07558.6 CEH15158.1 - 0.045 13.4 10.3 5 6.9 7.1 2.9 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region LON PF02190.11 CEH15158.1 - 0.05 13.2 0.8 0.053 13.1 0.5 1.0 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain bZIP_1 PF00170.16 CEH15158.1 - 0.054 13.4 10.8 25 4.9 7.5 2.7 1 1 0 1 1 1 0 bZIP transcription factor DUF904 PF06005.7 CEH15158.1 - 0.054 13.7 9.5 0.2 11.9 6.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 CEH15158.1 - 0.059 12.8 7.5 1.3 8.5 0.2 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF3776 PF12618.3 CEH15158.1 - 0.062 13.8 0.7 0.094 13.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) DUF1319 PF07028.6 CEH15158.1 - 0.077 13.1 3.0 0.089 12.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) CENP-F_leu_zip PF10473.4 CEH15158.1 - 0.082 12.7 7.3 0.1 12.4 5.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 CEH15158.1 - 0.087 12.0 6.8 0.087 12.0 4.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Lzipper-MIP1 PF14389.1 CEH15158.1 - 0.11 12.5 4.6 0.27 11.3 2.6 2.1 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 FlaC_arch PF05377.6 CEH15158.1 - 0.14 12.0 3.4 1.8 8.5 0.2 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 CEH15158.1 - 0.19 12.0 4.8 0.3 11.4 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Prefoldin PF02996.12 CEH15158.1 - 0.21 11.2 1.9 0.42 10.2 0.7 1.8 1 1 1 2 2 2 0 Prefoldin subunit TBPIP PF07106.8 CEH15158.1 - 0.21 11.1 5.2 0.22 11.0 3.6 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TSC22 PF01166.13 CEH15158.1 - 0.53 10.2 6.6 1.8 8.5 1.4 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.10 CEH15158.1 - 0.58 10.0 10.2 0.43 10.4 0.4 2.7 2 1 0 2 2 2 0 Basic region leucine zipper DUF2205 PF10224.4 CEH15158.1 - 0.96 9.0 7.0 4.3 6.9 3.9 2.0 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) HALZ PF02183.13 CEH15158.1 - 1.2 8.9 10.9 2.6 7.8 0.6 3.0 2 1 1 3 3 3 0 Homeobox associated leucine zipper Kinetocho_Slk19 PF12709.2 CEH15158.1 - 1.7 8.7 5.2 2.8 8.0 1.1 2.0 1 1 1 2 2 2 0 Central kinetochore-associated TMF_DNA_bd PF12329.3 CEH15158.1 - 2.3 8.0 9.8 2.3 8.0 0.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CEH15158.1 - 2.3 7.7 5.4 2.7 7.5 3.7 1.2 1 0 0 1 1 1 0 IncA protein M PF02370.11 CEH15158.1 - 2.6 8.7 6.2 6.1 7.5 0.2 3.2 3 1 1 4 4 4 0 M protein repeat MecA_N PF05223.6 CEH15159.1 - 0.016 15.2 0.3 0.019 15.0 0.2 1.1 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain AD PF09793.4 CEH15159.1 - 0.043 13.6 0.3 0.054 13.3 0.2 1.3 1 1 0 1 1 1 0 Anticodon-binding domain Hs1pro-1_C PF07014.7 CEH15159.1 - 0.1 11.9 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus DUF2018 PF09442.5 CEH15160.1 - 0.1 13.1 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) Ribosomal_60s PF00428.14 CEH15162.1 - 0.28 11.5 3.5 2.1 8.8 1.3 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Mu-conotoxin PF05374.7 CEH15163.1 - 0.1 12.4 1.0 0.25 11.1 0.7 1.7 1 0 0 1 1 1 0 Mu-Conotoxin Pyr_redox_3 PF13738.1 CEH15168.1 - 1.7e-25 90.3 0.2 5.2e-25 88.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CEH15168.1 - 3.5e-19 68.4 0.1 1.2e-15 56.7 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CEH15168.1 - 3e-12 46.1 1.4 1.5e-09 37.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CEH15168.1 - 1.7e-06 27.9 1.8 8e-06 25.7 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEH15168.1 - 7.8e-06 25.8 0.0 0.00022 21.1 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEH15168.1 - 1.1e-05 25.2 1.9 0.0063 16.3 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 CEH15168.1 - 0.00072 18.5 3.3 0.047 12.5 0.5 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase ThiF PF00899.16 CEH15168.1 - 0.011 15.5 1.1 1.1 9.0 0.1 2.7 3 0 0 3 3 3 0 ThiF family Malic_M PF03949.10 CEH15168.1 - 0.013 15.0 0.3 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Pyr_redox PF00070.22 CEH15168.1 - 0.021 15.2 1.9 8.6 6.8 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CEH15168.1 - 0.093 12.8 0.1 0.86 9.7 0.0 2.4 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 CEH15168.1 - 0.18 10.5 2.8 3.6 6.3 0.0 2.3 1 1 1 2 2 2 0 FAD binding domain KR PF08659.5 CEH15169.1 - 2.8e-25 89.0 2.7 7.8e-25 87.5 1.9 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CEH15169.1 - 6.9e-21 74.8 4.2 6.9e-21 74.8 2.9 2.1 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 CEH15169.1 - 6.4e-10 39.1 0.2 1.9e-09 37.6 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thioesterase PF00975.15 CEH15169.1 - 6e-09 36.4 0.0 1.3e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 CEH15169.1 - 0.0014 18.5 2.9 0.003 17.4 0.7 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF674 PF05056.7 CEH15170.1 - 0.099 11.2 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) Symplekin_C PF12295.3 CEH15171.1 - 1.9e-50 171.3 0.0 4.4e-50 170.1 0.0 1.6 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 CEH15171.1 - 5e-34 117.7 0.3 9.4e-34 116.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) DUF1764 PF08576.5 CEH15172.1 - 4.6e-05 24.1 1.3 0.00012 22.7 0.3 2.0 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) MMR_HSR1 PF01926.18 CEH15173.1 - 0.0017 18.3 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 CEH15173.1 - 0.0059 16.3 0.0 0.031 13.9 0.0 2.2 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 CEH15173.1 - 0.033 13.0 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 CEH15173.1 - 0.044 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CEH15173.1 - 0.23 11.6 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase G-alpha PF00503.15 CEH15173.1 - 8.5 4.9 5.6 1.6 7.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Sld5 PF05916.6 CEH15174.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 GINS complex protein Orexin PF02072.10 CEH15174.1 - 0.12 12.2 0.7 0.25 11.1 0.3 1.7 2 0 0 2 2 2 0 Prepro-orexin DUF1509 PF07420.6 CEH15174.1 - 0.13 11.5 7.9 0.19 10.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DAO PF01266.19 CEH15175.1 - 2.9e-43 148.1 0.7 6.3e-43 147.0 0.5 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CEH15175.1 - 7.8e-10 38.9 0.0 0.00038 20.3 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEH15175.1 - 3.7e-09 36.1 0.1 5.4e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 CEH15175.1 - 5.2e-09 35.4 0.1 0.00013 20.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 CEH15175.1 - 1.8e-08 34.7 0.0 0.00065 19.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEH15175.1 - 1.5e-07 31.7 0.0 2.9e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH15175.1 - 2.8e-07 30.4 0.3 9.5e-07 28.7 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CEH15175.1 - 1.2e-06 27.3 0.0 0.012 14.1 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 CEH15175.1 - 5.8e-05 22.9 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding 3HCDH_N PF02737.13 CEH15175.1 - 0.0003 20.4 0.0 0.0078 15.8 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 CEH15175.1 - 0.00089 18.2 0.0 1.2 7.9 0.0 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A TrkA_N PF02254.13 CEH15175.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Lycopene_cycl PF05834.7 CEH15175.1 - 0.0017 17.3 0.1 0.081 11.8 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.19 CEH15175.1 - 0.0018 17.4 0.0 0.44 9.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 CEH15175.1 - 0.0028 16.6 0.0 0.95 8.3 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 CEH15175.1 - 0.0054 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.11 CEH15175.1 - 0.0058 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Glyco_transf_4 PF13439.1 CEH15175.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 NAD_binding_2 PF03446.10 CEH15175.1 - 0.022 14.5 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 CEH15175.1 - 0.034 14.1 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 CEH15175.1 - 0.037 13.7 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 CEH15175.1 - 0.05 13.6 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF364 PF04016.7 CEH15175.1 - 0.089 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF364) YjgF_endoribonc PF14588.1 CEH15176.1 - 0.057 13.3 0.0 7 6.5 0.0 2.3 2 0 0 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease MutS_V PF00488.16 CEH15177.1 - 8.4e-78 261.0 0.1 1.3e-77 260.4 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CEH15177.1 - 3.7e-41 141.1 0.5 3.7e-41 141.1 0.4 2.6 4 0 0 4 4 4 1 MutS domain III MutS_I PF01624.15 CEH15177.1 - 1.5e-34 118.4 0.0 3.6e-34 117.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CEH15177.1 - 2.5e-13 50.2 0.0 6.3e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II zf-C2H2_3 PF13878.1 CEH15177.1 - 8.8e-12 44.3 0.5 2e-11 43.2 0.4 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_13 PF13880.1 CEH15177.1 - 7.9e-07 28.7 0.0 2.6e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 ESCO1/2 acetyl-transferase MutS_IV PF05190.13 CEH15177.1 - 0.0017 18.4 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV Acetyltransf_1 PF00583.19 CEH15177.1 - 0.005 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HPIP PF15226.1 CEH15178.1 - 0.03 14.3 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Bcr-Abl_Oligo PF09036.5 CEH15184.1 - 0.028 14.3 0.7 0.28 11.1 0.5 2.1 1 1 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain LMP PF04778.7 CEH15184.1 - 0.044 13.5 0.9 0.046 13.4 0.6 1.2 1 0 0 1 1 1 0 LMP repeated region PP_kinase PF02503.12 CEH15184.1 - 0.069 12.6 0.1 0.074 12.5 0.1 1.1 1 0 0 1 1 1 0 Polyphosphate kinase middle domain IncA PF04156.9 CEH15184.1 - 0.097 12.2 1.1 0.11 12.0 0.7 1.1 1 0 0 1 1 1 0 IncA protein H-kinase_dim PF02895.9 CEH15184.1 - 0.099 12.9 0.5 0.13 12.5 0.4 1.3 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF2968 PF11180.3 CEH15185.1 - 0.00095 18.6 17.4 0.001 18.4 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) ADIP PF11559.3 CEH15185.1 - 0.0012 18.7 16.5 0.007 16.2 10.6 1.9 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 CEH15185.1 - 0.016 14.4 1.5 0.017 14.3 1.1 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CEH15185.1 - 0.05 13.4 17.0 0.07 12.9 11.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 CEH15185.1 - 0.056 12.4 14.7 0.067 12.2 10.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3073 PF11273.3 CEH15185.1 - 0.062 13.8 9.0 0.91 10.0 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) LPP PF04728.8 CEH15185.1 - 0.063 13.0 5.2 0.082 12.7 2.3 2.1 1 1 1 2 2 2 0 Lipoprotein leucine-zipper ATG16 PF08614.6 CEH15185.1 - 0.064 13.0 13.9 0.075 12.8 9.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) IncA PF04156.9 CEH15185.1 - 0.077 12.5 16.2 0.089 12.3 11.2 1.1 1 0 0 1 1 1 0 IncA protein DUF4164 PF13747.1 CEH15185.1 - 0.16 12.1 14.1 0.053 13.6 3.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) HALZ PF02183.13 CEH15185.1 - 0.17 11.5 0.1 0.17 11.5 0.1 2.9 2 1 0 3 3 3 0 Homeobox associated leucine zipper Fmp27_WPPW PF10359.4 CEH15185.1 - 0.19 10.1 9.3 0.22 9.9 6.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Baculo_PEP_C PF04513.7 CEH15185.1 - 0.27 11.0 2.5 0.32 10.8 1.7 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rootletin PF15035.1 CEH15185.1 - 0.32 10.9 12.1 0.38 10.7 8.4 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4094 PF13334.1 CEH15185.1 - 0.72 10.2 9.8 0.32 11.4 4.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) bZIP_Maf PF03131.12 CEH15185.1 - 1.4 9.2 13.0 5 7.4 2.1 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor Allexi_40kDa PF05549.6 CEH15185.1 - 2.1 7.5 5.2 2.1 7.5 3.6 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF904 PF06005.7 CEH15185.1 - 2.1 8.6 14.5 1.2 9.5 2.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF948 PF06103.6 CEH15185.1 - 2.3 8.1 5.7 2.5 8.0 2.4 1.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 CEH15185.1 - 2.6 6.3 10.6 2.8 6.3 7.3 1.1 1 0 0 1 1 1 0 AAA domain Prominin PF05478.6 CEH15185.1 - 3.3 5.1 6.1 3.4 5.0 4.2 1.0 1 0 0 1 1 1 0 Prominin PCEMA1 PF07418.6 CEH15185.1 - 3.6 6.8 9.6 4.1 6.6 6.7 1.0 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 V_ATPase_I PF01496.14 CEH15185.1 - 3.7 5.2 9.6 3.9 5.1 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 CEH15185.1 - 4.1 7.0 12.7 5 6.7 8.8 1.2 1 0 0 1 1 1 0 Mnd1 family Vfa1 PF08432.5 CEH15185.1 - 4.7 7.1 11.1 4.4 7.2 7.1 1.4 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3450 PF11932.3 CEH15185.1 - 7.3 5.7 17.6 5.3 6.2 10.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Muted PF14942.1 CEH15185.1 - 7.5 6.4 12.1 3.8 7.3 5.6 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF4140 PF13600.1 CEH15185.1 - 7.9 6.9 13.9 5.1 7.6 3.2 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ax_dynein_light PF10211.4 CEH15185.1 - 8.8 6.1 14.2 2.9 7.6 4.9 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain GAS PF13851.1 CEH15186.1 - 5.3 6.1 36.8 0.62 9.2 5.1 3.5 2 2 0 3 3 3 0 Growth-arrest specific micro-tubule binding LMBR1 PF04791.11 CEH15186.1 - 7.1 5.0 10.8 0.22 10.0 1.4 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein LOH1CR12 PF10158.4 CEH15188.1 - 4e-05 23.4 0.4 0.98 9.2 0.0 3.0 1 1 2 3 3 3 2 Tumour suppressor protein Ribosom_S12_S23 PF00164.20 CEH15188.1 - 6.1e-05 22.4 0.1 0.069 12.5 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S12/S23 DUF1727 PF08353.5 CEH15188.1 - 8.8e-05 22.0 0.1 0.052 13.1 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1727) DUF1664 PF07889.7 CEH15188.1 - 0.0005 19.8 0.3 0.4 10.4 0.0 2.4 1 1 2 3 3 3 3 Protein of unknown function (DUF1664) GATase_2 PF00310.16 CEH15188.1 - 0.0057 15.3 0.1 2.1 6.9 0.0 2.7 1 1 2 3 3 3 2 Glutamine amidotransferases class-II Lipase_3 PF01764.20 CEH15188.1 - 0.015 14.9 0.1 8.2 6.0 0.0 2.9 2 1 1 3 3 3 0 Lipase (class 3) DUF1786 PF08735.5 CEH15188.1 - 0.02 14.1 0.1 0.1 11.7 0.0 1.9 1 1 1 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) BHD_3 PF10405.4 CEH15188.1 - 0.043 13.5 0.0 4.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 3 Baculo_FP PF03258.9 CEH15188.1 - 0.052 12.6 0.2 1.2 8.1 0.1 2.1 1 1 2 3 3 3 0 Baculovirus FP protein MtrB PF05440.7 CEH15188.1 - 0.076 13.0 0.1 9.1 6.4 0.0 2.5 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF2437 PF10370.4 CEH15190.1 - 0.097 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) PTH2 PF01981.11 CEH15191.1 - 1.4e-47 160.1 0.2 2e-47 159.6 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PC_rep PF01851.17 CEH15192.1 - 3.3e-46 152.9 16.1 2.5e-09 36.8 0.0 9.6 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CEH15192.1 - 2.2e-17 63.1 3.4 8.5e-11 41.9 0.0 4.5 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 CEH15192.1 - 2.4e-07 30.2 2.5 1.9 8.8 0.1 6.1 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 CEH15192.1 - 2.6e-07 30.9 2.9 0.0095 16.3 0.1 5.0 2 1 2 4 4 4 2 HEAT-like repeat HEAT_PBS PF03130.11 CEH15192.1 - 0.0029 17.9 3.7 30 5.4 0.0 5.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Utp13 PF08625.6 CEH15192.1 - 0.0083 15.7 0.1 0.026 14.1 0.0 1.9 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain DUF3140 PF11338.3 CEH15193.1 - 0.011 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Dynamin_N PF00350.18 CEH15194.1 - 1.5e-16 60.6 2.7 1.7e-16 60.4 0.0 2.5 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 CEH15194.1 - 3.7e-11 42.9 0.0 2.5e-10 40.3 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEH15194.1 - 4.6e-09 35.9 0.2 5.4e-08 32.4 0.2 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CEH15194.1 - 0.00025 21.5 0.3 0.021 15.3 0.2 2.9 1 1 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 CEH15194.1 - 0.002 17.6 0.0 0.0079 15.7 0.0 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arf PF00025.16 CEH15194.1 - 0.0057 15.9 0.4 0.67 9.1 0.0 2.6 2 0 0 2 2 2 1 ADP-ribosylation factor family IIGP PF05049.8 CEH15194.1 - 0.0087 14.9 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 CEH15194.1 - 0.057 12.6 0.0 0.48 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 CEH15194.1 - 0.058 13.7 0.1 23 5.2 0.1 3.0 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 CEH15195.1 - 1.7e-43 148.0 0.0 1.1e-42 145.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH15195.1 - 1.5e-24 85.6 0.0 3.7e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MMR_HSR1 PF01926.18 CEH15196.1 - 2.9e-17 62.6 0.4 2.4e-13 50.0 0.1 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEH15196.1 - 9.4e-08 31.7 0.0 9.3e-05 21.9 0.0 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CEH15196.1 - 3.9e-07 29.4 0.1 8.3e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CEH15196.1 - 0.00022 21.1 0.9 0.59 9.9 0.3 3.3 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 CEH15196.1 - 0.00057 19.1 0.2 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Virul_Fac PF10139.4 CEH15196.1 - 0.017 13.0 0.2 0.029 12.3 0.2 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor Miro PF08477.8 CEH15196.1 - 0.044 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 CEH15196.1 - 0.077 12.2 0.1 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.11 CEH15196.1 - 0.081 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 AIG1 family B-block_TFIIIC PF04182.7 CEH15197.1 - 4.7e-08 32.7 0.0 1.3e-06 28.1 0.0 2.7 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_20 PF12840.2 CEH15197.1 - 0.012 15.3 0.0 0.042 13.6 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain POPLD PF08170.7 CEH15197.1 - 0.037 13.8 0.1 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 POPLD (NUC188) domain CIAPIN1 PF05093.8 CEH15199.1 - 6.1e-31 106.4 6.7 8.2e-30 102.8 4.6 2.4 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3714 PF12508.3 CEH15199.1 - 0.38 10.1 4.0 0.78 9.1 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3714) LIP PF03583.9 CEH15203.1 - 3.6e-43 147.8 0.0 5.7e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 CEH15203.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 CEH15203.1 - 0.038 13.6 0.1 0.078 12.5 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) His_Phos_1 PF00300.17 CEH15205.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) mRNA_cap_C PF03919.10 CEH15206.1 - 1.9e-09 37.7 0.1 9.6e-09 35.5 0.0 2.0 1 1 1 2 2 2 1 mRNA capping enzyme, C-terminal domain DUF4611 PF15387.1 CEH15206.1 - 0.02 15.0 0.9 0.041 14.0 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) mRNA_cap_enzyme PF01331.14 CEH15207.1 - 1.1e-25 90.5 0.0 1.7e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 CEH15207.1 - 4.2e-06 26.2 0.0 0.00014 21.3 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_pol_E_B PF04042.11 CEH15208.1 - 1.5e-43 148.5 0.1 1.9e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PPR_2 PF13041.1 CEH15209.1 - 0.00094 19.1 0.0 0.69 9.9 0.0 3.4 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.1 CEH15209.1 - 4.1 7.9 5.0 1.3e+02 3.2 0.0 5.3 7 0 0 7 7 7 0 Pentatricopeptide repeat domain Proteasome PF00227.21 CEH15210.1 - 1e-51 174.9 0.1 1.3e-51 174.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit NTP_transferase PF00483.18 CEH15211.1 - 2.6e-39 135.0 0.0 1.1e-38 132.9 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.13 CEH15211.1 - 2.9e-06 26.9 1.0 5.2e-06 26.1 0.2 1.7 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Zw10 PF06248.8 CEH15212.1 - 4.5e-11 41.6 0.0 1.3e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 LigA PF07746.6 CEH15212.1 - 0.37 10.8 2.4 19 5.3 0.0 3.3 3 0 0 3 3 3 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Dsl1_C PF11989.3 CEH15212.1 - 0.75 8.9 0.0 1.7 7.7 0.0 1.5 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal HECT PF00632.20 CEH15213.1 - 2.5e-90 302.8 0.0 3.7e-90 302.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CEH15213.1 - 1.1e-32 111.4 20.3 4e-11 42.5 2.1 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CEH15213.1 - 1.1e-16 60.4 0.3 2.2e-16 59.4 0.2 1.5 1 0 0 1 1 1 1 C2 domain Mnd1 PF03962.10 CEH15214.1 - 0.068 12.8 4.7 0.1 12.2 3.3 1.3 1 0 0 1 1 1 0 Mnd1 family S10_plectin PF03501.10 CEH15215.1 - 1.1e-40 137.4 0.0 1.3e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Ribosomal_L44 PF00935.14 CEH15216.1 - 1.4e-34 117.9 11.2 2e-34 117.4 7.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L34e PF01199.13 CEH15217.1 - 6.9e-37 125.5 5.5 9e-37 125.1 3.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 CEH15217.1 - 0.0066 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c7 FhuF_C PF11575.3 CEH15217.1 - 0.39 10.3 4.5 11 5.7 0.5 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Ribosomal_S30 PF04758.9 CEH15218.1 - 3.9e-29 100.1 8.1 4.3e-29 100.0 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S14 PF00253.16 CEH15219.1 - 2e-17 62.2 1.7 2.8e-17 61.8 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e A2L_zn_ribbon PF08792.5 CEH15219.1 - 0.47 9.9 2.6 0.98 8.9 1.8 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain Prim_Zn_Ribbon PF08273.7 CEH15219.1 - 4.7 7.3 7.1 9.8 6.3 1.3 2.2 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase FAD_binding_3 PF01494.14 CEH15225.1 - 0.087 11.8 0.1 0.09 11.8 0.1 1.0 1 0 0 1 1 1 0 FAD binding domain Vps51 PF08700.6 CEH15226.1 - 4.3e-11 42.5 0.0 2.5e-10 40.0 0.0 2.4 1 0 0 1 1 1 1 Vps51/Vps67 TrmB PF01978.14 CEH15226.1 - 0.09 12.4 2.1 24 4.7 0.1 3.7 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB WD40 PF00400.27 CEH15227.1 - 1.8e-29 100.5 16.5 1.1e-06 28.2 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CEH15227.1 - 0.085 12.6 0.0 0.85 9.4 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 CEH15227.1 - 0.17 10.0 1.9 12 3.9 0.1 3.0 2 1 0 3 3 3 0 Nucleoporin Nup120/160 POT1 PF02765.12 CEH15228.1 - 6.6e-06 26.0 0.0 3.3e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Reo_sigmaC PF04582.7 CEH15229.1 - 0.11 11.7 3.9 0.15 11.2 2.7 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CEH15229.1 - 2 8.2 25.7 7.3 6.4 8.6 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.8 CEH15229.1 - 4.7 8.0 12.6 8.4 7.1 4.2 2.9 1 1 2 3 3 3 0 Occludin homology domain V_ATPase_I PF01496.14 CEH15229.1 - 5.3 4.7 11.9 6.9 4.3 8.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DnaJ PF00226.26 CEH15233.1 - 1e-18 66.7 0.2 3.8e-18 64.9 0.1 2.1 1 0 0 1 1 1 1 DnaJ domain MSA_2 PF00985.12 CEH15233.1 - 1 9.5 7.3 2.3 8.3 5.1 1.6 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family TEX15 PF15326.1 CEH15233.1 - 1.1 8.8 5.6 2 7.9 3.9 1.4 1 0 0 1 1 1 0 Testis expressed sequence 15 Proteasome PF00227.21 CEH15234.1 - 9.9e-47 158.6 0.0 1.4e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEH15234.1 - 1.4e-12 46.7 0.2 2.8e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fungal_trans PF04082.13 CEH15235.1 - 9.8e-05 21.3 0.0 0.00027 19.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lipase_3 PF01764.20 CEH15236.1 - 8.3e-08 31.9 0.0 2.6e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CEH15236.1 - 0.00098 19.0 0.1 0.00098 19.0 0.1 3.0 4 0 0 4 4 4 1 Alpha/beta hydrolase family MMR_HSR1 PF01926.18 CEH15236.1 - 0.0016 18.4 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEH15236.1 - 0.0041 16.5 0.0 0.049 13.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Abhydrolase_5 PF12695.2 CEH15236.1 - 0.0043 16.8 0.0 0.015 15.0 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Miro PF08477.8 CEH15236.1 - 0.018 15.5 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 CEH15236.1 - 0.068 12.9 0.1 3.2 7.5 0.0 2.3 1 1 1 2 2 2 0 Dynamin family G10 PF01125.12 CEH15237.1 - 4.8e-62 207.8 2.9 5.4e-62 207.6 2.0 1.0 1 0 0 1 1 1 1 G10 protein DNA_RNApol_7kD PF03604.8 CEH15237.1 - 0.033 13.6 3.7 0.033 13.6 2.6 1.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit MiAMP1 PF09117.5 CEH15238.1 - 0.052 13.9 0.5 0.064 13.6 0.4 1.3 1 0 0 1 1 1 0 MiAMP1 DUF316 PF03761.10 CEH15238.1 - 0.074 12.3 0.1 0.083 12.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF316) V_ATPase_I PF01496.14 CEH15239.1 - 0.051 11.4 0.0 0.068 11.0 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 CEH15239.1 - 0.064 10.5 9.6 0.082 10.2 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 CEH15239.1 - 0.14 11.7 3.0 0.16 11.5 1.2 1.7 2 0 0 2 2 2 0 IncA protein Fez1 PF06818.10 CEH15239.1 - 0.22 11.4 4.1 0.36 10.8 2.8 1.4 1 0 0 1 1 1 0 Fez1 DUF2968 PF11180.3 CEH15239.1 - 0.54 9.6 12.5 0.26 10.6 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Patched PF02460.13 CEH15240.1 - 2e-57 194.7 0.1 6.9e-32 110.2 0.0 3.8 3 1 0 3 3 3 3 Patched family Sterol-sensing PF12349.3 CEH15240.1 - 1.1e-39 135.3 11.8 5.3e-22 77.9 0.2 3.3 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation Vpu PF00558.14 CEH15240.1 - 0.42 10.1 0.0 1.5 8.3 0.0 1.9 2 0 0 2 2 2 0 Vpu protein ACR_tran PF00873.14 CEH15240.1 - 0.73 7.1 3.8 1.1 6.6 2.7 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MMPL PF03176.10 CEH15240.1 - 9.7 4.7 19.6 0.088 11.5 2.1 3.0 3 0 0 3 3 3 0 MMPL family TFIID-18kDa PF02269.11 CEH15241.1 - 7.5e-17 60.9 0.1 2.6e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit AD PF09793.4 CEH15242.1 - 1.6e-18 66.2 0.0 2.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain GTP_EFTU PF00009.22 CEH15244.1 - 4.6e-28 97.9 0.0 9.8e-28 96.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CEH15244.1 - 7.3e-20 70.5 0.9 4.4e-09 36.0 0.0 2.9 3 0 0 3 3 3 2 Elongation Factor G, domain II RGS PF00615.14 CEH15245.1 - 1.5e-39 134.7 0.0 3.3e-39 133.6 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 CEH15245.1 - 1.3e-08 34.4 0.0 2e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Asp PF00026.18 CEH15246.1 - 2.9e-28 99.0 0.0 6.8e-28 97.8 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Lamp PF01299.12 CEH15246.1 - 0.0043 16.2 0.0 0.0078 15.3 0.0 1.4 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Shisa PF13908.1 CEH15246.1 - 0.0057 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator NOA36 PF06524.7 CEH15247.1 - 0.051 12.8 4.9 0.075 12.2 3.4 1.3 1 0 0 1 1 1 0 NOA36 protein CARD PF00619.16 CEH15247.1 - 2.4 8.0 8.1 0.68 9.8 0.6 2.3 2 0 0 2 2 2 0 Caspase recruitment domain Proteasome PF00227.21 CEH15248.1 - 6.6e-33 113.5 0.0 1e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit AMP-binding PF00501.23 CEH15249.1 - 2.5e-76 256.7 0.0 3.6e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CEH15249.1 - 9.2e-65 218.0 0.1 1.6e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 CEH15249.1 - 3.5e-11 43.2 0.0 1.3e-10 41.4 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 CEH15249.1 - 5.2e-08 33.7 0.0 2.5e-07 31.5 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 CEH15249.1 - 8.8e-08 31.8 0.0 2.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CEH15249.1 - 0.00015 20.5 0.0 0.019 13.6 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CEH15249.1 - 0.049 12.5 0.0 3 6.6 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Condensation PF00668.15 CEH15249.1 - 0.065 12.0 0.0 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 Condensation domain DUF2370 PF10176.4 CEH15250.1 - 2.8e-73 246.1 1.8 6.6e-72 241.6 0.0 3.1 3 1 0 3 3 3 2 Protein of unknown function (DUF2370) DUF4220 PF13968.1 CEH15251.1 - 0.34 9.9 14.3 0.27 10.2 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4220) TRP PF06011.7 CEH15252.1 - 1.9e-59 201.4 23.1 1.4e-58 198.5 16.0 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Cu2_monoox_C PF03712.10 CEH15255.1 - 0.17 11.1 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain XhlA PF10779.4 CEH15255.1 - 8.2 6.4 6.5 1.1 9.1 0.6 2.7 2 0 0 2 2 2 0 Haemolysin XhlA KR PF08659.5 CEH15256.1 - 0.0074 15.9 0.0 0.019 14.6 0.0 1.8 2 1 0 2 2 2 1 KR domain CD99L2 PF12301.3 CEH15257.1 - 1.7 8.3 6.3 0.15 11.7 0.5 2.0 2 1 0 2 2 2 0 CD99 antigen like protein 2 Cytotoxic PF09000.5 CEH15259.1 - 0.062 13.3 0.3 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 Cytotoxic RAI16-like PF10257.4 CEH15260.1 - 1.2e-47 162.6 0.0 2e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Ank_2 PF12796.2 CEH15261.1 - 6.3e-43 145.0 1.7 9.2e-20 70.7 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEH15261.1 - 8.6e-31 105.2 1.9 1.1e-10 41.3 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CEH15261.1 - 3.3e-30 102.3 0.5 5.1e-07 29.1 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 CEH15261.1 - 2.7e-26 91.4 0.0 3.8e-12 46.3 0.1 3.6 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH15261.1 - 4.6e-19 66.6 0.2 0.0011 18.9 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.16 CEH15261.1 - 4.3e-18 64.9 6.4 4.3e-18 64.9 4.5 2.3 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.1 CEH15261.1 - 1.8e-09 37.2 5.1 1.8e-09 37.2 3.5 3.3 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 CEH15261.1 - 0.0029 17.6 1.8 0.0029 17.6 1.2 2.6 3 0 0 3 3 3 1 RING-H2 zinc finger Dynactin_p62 PF05502.8 CEH15261.1 - 1.5 7.4 5.5 4 6.0 2.1 2.3 2 0 0 2 2 2 0 Dynactin p62 family zinc-ribbons_6 PF07191.7 CEH15261.1 - 2.5 7.9 11.9 1.1 9.1 2.1 3.0 3 0 0 3 3 3 0 zinc-ribbons FYVE_2 PF02318.11 CEH15261.1 - 2.7 7.9 9.0 0.042 13.7 1.0 1.9 2 0 0 2 2 1 0 FYVE-type zinc finger LRR_4 PF12799.2 CEH15262.1 - 4e-06 26.3 0.7 5.9e-05 22.5 0.1 2.2 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEH15262.1 - 0.00011 21.8 1.1 0.00024 20.7 0.8 1.6 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CEH15262.1 - 0.0033 17.2 1.5 0.88 9.8 0.0 3.2 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 CEH15262.1 - 2.8 8.5 5.4 8.8 7.0 0.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat LRR_8 PF13855.1 CEH15263.1 - 1.6e-12 47.0 6.8 7.5e-07 28.8 0.1 3.5 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CEH15263.1 - 9.4e-12 44.2 8.6 0.00011 21.7 1.3 3.7 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEH15263.1 - 0.0031 17.3 12.2 7 7.1 0.1 5.6 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 CEH15263.1 - 0.0075 16.2 6.0 0.58 10.3 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 CEH15263.1 - 0.01 15.8 9.7 24 5.7 0.0 5.3 4 1 1 5 5 5 0 Leucine rich repeat Cupin_3 PF05899.7 CEH15265.1 - 0.00053 19.3 0.0 0.00078 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 CEH15265.1 - 0.003 17.1 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ YlqD PF11068.3 CEH15265.1 - 0.024 14.6 0.0 0.037 14.0 0.0 1.3 1 1 0 1 1 1 0 YlqD protein Pirin_C PF05726.8 CEH15265.1 - 0.036 14.1 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Pirin C-terminal cupin domain THEG PF14912.1 CEH15266.1 - 0.048 14.2 0.1 0.063 13.8 0.0 1.3 1 0 0 1 1 1 0 Testicular haploid expressed repeat Glyco_transf_22 PF03901.12 CEH15267.1 - 1e-14 54.4 5.8 1.4e-14 53.9 4.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1119 PF06550.6 CEH15267.1 - 0.0061 15.7 1.4 0.01 14.9 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1119) O-antigen_lig PF13425.1 CEH15267.1 - 0.52 10.2 6.3 1.2 9.1 4.4 1.7 1 1 0 1 1 1 0 O-antigen ligase like membrane protein COX6B PF02297.12 CEH15268.1 - 3.6e-23 81.3 1.3 6.8e-23 80.4 0.9 1.4 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb COX17 PF05051.8 CEH15268.1 - 0.044 13.8 0.2 12 6.0 0.2 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CHD5 PF04420.9 CEH15269.1 - 2.4e-32 111.8 0.2 2.4e-32 111.8 0.1 1.7 1 1 1 2 2 2 1 CHD5-like protein IncA PF04156.9 CEH15269.1 - 1.2 8.7 6.5 2.4 7.6 1.9 2.2 2 0 0 2 2 2 0 IncA protein Wzz PF02706.10 CEH15269.1 - 7.2 6.4 7.1 0.81 9.5 0.2 2.1 1 1 0 2 2 2 0 Chain length determinant protein DUF3722 PF12519.3 CEH15277.1 - 1.2e-85 286.8 0.1 1.8e-85 286.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 CEH15277.1 - 0.00018 20.8 0.0 0.017 14.4 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic porin MFS_1 PF07690.11 CEH15278.1 - 4.1e-30 104.7 28.3 4.1e-30 104.7 19.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH15278.1 - 2.3e-10 39.6 14.8 9.7e-10 37.5 10.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 CEH15278.1 - 2e-05 22.9 0.7 4e-05 22.0 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Kinesin PF00225.18 CEH15279.1 - 2.1e-109 365.3 0.0 3.2e-109 364.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain PAP_central PF04928.12 CEH15279.1 - 0.011 14.5 2.9 0.023 13.5 2.0 1.4 1 0 0 1 1 1 0 Poly(A) polymerase central domain Herpes_UL6 PF01763.11 CEH15279.1 - 0.013 13.7 5.9 0.026 12.7 4.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like UPF0193 PF05250.6 CEH15279.1 - 0.013 15.0 4.4 0.024 14.2 3.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) DUF904 PF06005.7 CEH15279.1 - 0.11 12.8 6.6 0.44 10.8 4.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF904) AAA_11 PF13086.1 CEH15279.1 - 0.64 9.5 11.5 0.0098 15.4 2.0 2.3 3 0 0 3 3 3 0 AAA domain COG5 PF10392.4 CEH15279.1 - 0.98 9.3 7.2 2.2 8.2 5.0 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 V_ATPase_I PF01496.14 CEH15279.1 - 1.5 6.5 7.2 2 6.1 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CEH15279.1 - 6.7 7.1 8.3 17 5.8 5.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) RseA_C PF03873.8 CEH15280.1 - 0.093 12.6 0.6 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain VMA21 PF09446.5 CEH15281.1 - 4.1e-09 36.2 10.4 6.5e-09 35.5 7.2 1.3 1 0 0 1 1 1 1 VMA21-like domain Polysacc_synt_3 PF13440.1 CEH15281.1 - 0.0047 16.4 0.1 0.0054 16.2 0.1 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Cyt_c_ox_IV PF12270.3 CEH15281.1 - 0.018 14.7 0.3 0.022 14.5 0.2 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF4245 PF14030.1 CEH15281.1 - 0.045 13.4 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) OppC_N PF12911.2 CEH15281.1 - 0.17 11.2 0.6 10 5.5 0.1 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C ECH PF00378.15 CEH15284.1 - 1e-20 73.9 0.1 1.9e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Formyl_trans_N PF00551.14 CEH15284.1 - 1.4e-09 37.7 0.1 5.6e-08 32.5 0.0 2.8 1 1 1 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.13 CEH15284.1 - 0.0051 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain ECH PF00378.15 CEH15285.1 - 6.9e-36 123.5 0.0 4e-25 88.3 0.3 2.2 1 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family AAA_35 PF14516.1 CEH15285.1 - 0.05 12.2 0.0 0.073 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Spore-coat_CotZ PF10612.4 CEH15286.1 - 0.055 13.3 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Spore coat protein Z UPF0160 PF03690.8 CEH15287.1 - 2e-114 382.3 0.0 2.3e-114 382.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) HCO3_cotransp PF00955.16 CEH15288.1 - 5.2e-39 134.2 14.6 2.2e-22 79.4 3.5 3.6 1 1 1 2 2 2 2 HCO3- transporter family Zip PF02535.17 CEH15288.1 - 0.025 13.5 0.0 0.025 13.5 0.0 6.8 2 1 0 2 2 2 0 ZIP Zinc transporter Suf PF05843.9 CEH15289.1 - 2.8 7.6 12.5 0.48 10.1 4.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) X PF00739.14 CEH15289.1 - 5.8 6.8 12.7 0.23 11.3 0.3 2.7 2 1 0 2 2 2 0 Trans-activation protein X Complex1_LYR PF05347.10 CEH15290.1 - 5.1e-10 38.9 0.1 7.5e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CEH15290.1 - 1.2e-07 31.7 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Hist_deacetyl PF00850.14 CEH15291.1 - 1.5e-90 303.7 0.0 2.3e-90 303.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 CEH15291.1 - 1.7e-08 34.0 0.0 4.1e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Arb2 domain DUF1675 PF07897.6 CEH15292.1 - 0.023 14.5 3.9 0.034 14.0 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) BNIP2 PF12496.3 CEH15292.1 - 4.6 7.4 6.8 7.8 6.6 4.6 1.5 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Sua5_yciO_yrdC PF01300.13 CEH15295.1 - 8.9e-52 174.9 0.0 1.8e-48 164.1 0.0 2.2 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CEH15295.1 - 3.1e-08 33.7 0.0 4.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding AraC_binding_2 PF14525.1 CEH15295.1 - 0.13 11.7 4.7 0.059 12.9 1.5 1.7 2 0 0 2 2 2 0 AraC-binding-like domain Bax1-I PF01027.15 CEH15297.1 - 0.23 11.0 12.1 0.34 10.4 8.4 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 AA_permease PF00324.16 CEH15298.1 - 6.2e-97 324.9 34.9 7.1e-97 324.7 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEH15298.1 - 1.3e-28 99.7 38.6 1.6e-28 99.4 26.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF648 PF04890.8 CEH15298.1 - 0.24 10.5 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) Pox_P21 PF05313.7 CEH15298.1 - 4.1 6.6 7.5 0.6 9.3 1.6 2.1 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Arm PF00514.18 CEH15299.1 - 7.2e-18 63.6 24.2 0.00018 21.1 0.1 7.7 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CEH15299.1 - 2.3e-05 24.5 26.5 1.5 9.1 1.5 7.2 3 3 3 6 6 6 3 HEAT repeats HEAT PF02985.17 CEH15299.1 - 0.0082 16.1 25.1 1.4 9.2 0.0 8.6 9 0 0 9 9 9 2 HEAT repeat DUF4042 PF13251.1 CEH15299.1 - 0.035 13.5 0.6 0.08 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) M11L PF11099.3 CEH15299.1 - 0.038 13.7 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Apoptosis regulator M11L like Ric8 PF10165.4 CEH15299.1 - 0.081 11.7 3.6 0.33 9.7 0.1 2.9 2 1 2 4 4 4 0 Guanine nucleotide exchange factor synembryn HEAT_EZ PF13513.1 CEH15299.1 - 5.6 7.5 37.2 0.84 10.2 0.2 8.0 7 2 1 8 8 8 0 HEAT-like repeat ELL PF10390.4 CEH15300.1 - 5.5e-06 25.8 7.1 9e-06 25.1 3.2 5.1 3 2 0 3 3 3 2 RNA polymerase II elongation factor ELL DUF4415 PF14384.1 CEH15300.1 - 0.0074 16.4 0.0 0.053 13.6 0.0 2.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4415) Tom37_C PF11801.3 CEH15301.1 - 0.2 11.4 1.6 0.25 11.1 1.1 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain ubiquitin PF00240.18 CEH15302.1 - 5.1e-17 61.0 0.1 7.6e-17 60.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CEH15302.1 - 7.6e-10 38.3 0.6 1.2e-09 37.7 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CEH15302.1 - 1.2e-06 28.5 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UBA PF00627.26 CEH15302.1 - 5.8e-05 22.7 0.1 0.00016 21.4 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.1 CEH15302.1 - 0.00015 21.6 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEH15302.1 - 0.12 12.6 0.3 0.34 11.2 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain G_glu_transpept PF01019.16 CEH15303.1 - 4.7e-52 177.1 0.1 1.8e-45 155.4 0.0 2.1 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase Ribosomal_L10 PF00466.15 CEH15305.1 - 3e-13 49.5 0.0 4.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Nucleoplasmin PF03066.10 CEH15305.1 - 0.27 10.7 3.7 0.48 9.9 2.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CEH15305.1 - 0.57 10.4 7.5 1.2 9.4 5.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 CEH15305.1 - 1.2 9.5 5.6 2.9 8.2 3.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 CEH15305.1 - 2.4 6.7 6.2 3.7 6.1 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3425 PF11905.3 CEH15307.1 - 2e-20 73.0 4.1 3.4e-20 72.3 1.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 CEH15307.1 - 0.064 13.2 8.5 0.12 12.3 5.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 CEH15307.1 - 0.55 10.0 12.4 1.2 9.0 8.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper zf-C2H2_4 PF13894.1 CEH15309.1 - 0.05 13.9 4.0 1.4 9.3 2.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CEH15309.1 - 0.56 10.6 3.3 13 6.4 2.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3808 PF10300.4 CEH15310.1 - 2.7e-85 286.7 0.1 5.7e-85 285.6 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 CEH15310.1 - 0.005 16.4 3.6 0.47 10.1 0.3 3.7 3 1 1 4 4 4 1 TPR repeat TPR_4 PF07721.9 CEH15310.1 - 0.041 14.3 2.1 0.083 13.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEH15310.1 - 0.045 13.6 0.5 2.5 8.1 0.0 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEH15310.1 - 0.047 13.6 12.2 0.19 11.6 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 CEH15310.1 - 0.19 11.8 4.3 0.29 11.3 0.7 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CEH15310.1 - 1.1 10.0 5.6 13 6.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Lyase_aromatic PF00221.14 CEH15311.1 - 1.1e-83 281.2 3.5 1.7e-63 214.7 1.2 2.2 1 1 0 2 2 2 2 Aromatic amino acid lyase Hemerythrin PF01814.18 CEH15311.1 - 0.11 12.6 3.1 6.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Pkinase PF00069.20 CEH15313.1 - 5.6e-58 196.1 0.0 2e-37 128.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15313.1 - 2.5e-24 85.7 0.0 4e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 CEH15313.1 - 1.5e-09 37.7 0.0 4e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 CEH15313.1 - 2.6e-07 29.9 0.1 3.4e-05 22.9 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 CEH15313.1 - 0.00038 20.2 0.0 0.0046 16.7 0.0 2.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family PAS_9 PF13426.1 CEH15313.1 - 0.0014 19.0 0.0 0.0048 17.2 0.0 1.9 2 0 0 2 2 1 1 PAS domain Seadorna_VP7 PF07387.6 CEH15313.1 - 0.012 14.5 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 CEH15313.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_3 PF08447.6 CEH15313.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS PF00989.19 CEH15313.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 PAS fold Serglycin PF04360.7 CEH15313.1 - 8.5 6.0 8.3 25 4.5 5.7 1.7 1 0 0 1 1 1 0 Serglycin Ribosomal_S18 PF01084.15 CEH15314.1 - 1.5e-14 53.5 0.1 3.6e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 DUF2802 PF10975.3 CEH15314.1 - 0.013 15.2 3.8 0.59 9.9 1.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) HTH_27 PF13463.1 CEH15314.1 - 0.048 13.9 0.0 0.091 13.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain Ribosomal_L29e PF01779.12 CEH15315.1 - 8e-21 73.6 10.3 1.2e-20 73.0 7.2 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family DUF4505 PF14956.1 CEH15316.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) TAP_C PF03943.8 CEH15317.1 - 2.8e-10 39.4 0.0 6.1e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 CEH15317.1 - 0.0022 17.6 4.1 0.015 14.9 0.6 3.1 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CEH15317.1 - 0.098 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat HK PF02110.10 CEH15318.1 - 1.1e-63 214.6 6.8 5.4e-63 212.4 1.8 2.4 2 1 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 CEH15318.1 - 1.3e-45 154.7 0.1 2.1e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 CEH15318.1 - 6.3e-05 22.2 0.1 0.00014 21.1 0.1 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF1935 PF09149.5 CEH15320.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) MAGE PF01454.14 CEH15322.1 - 4.2e-30 104.5 0.0 1.3e-26 93.2 0.0 2.8 1 1 1 2 2 2 2 MAGE family MarR PF01047.17 CEH15322.1 - 0.045 13.4 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 MarR family CoaE PF01121.15 CEH15324.1 - 2.3e-51 173.7 0.0 3.4e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 CEH15324.1 - 7e-06 26.8 0.0 1.5e-05 25.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEH15324.1 - 0.0033 17.7 0.0 0.013 15.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEH15324.1 - 0.0061 16.4 0.4 0.021 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain Cation_ATPase_N PF00690.21 CEH15324.1 - 0.025 14.0 0.1 0.077 12.4 0.0 1.9 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus AAA_28 PF13521.1 CEH15324.1 - 0.071 13.0 0.0 0.098 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain EI24 PF07264.6 CEH15326.1 - 0.00065 19.1 0.2 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FA_desaturase PF00487.19 CEH15326.1 - 0.00096 18.6 1.4 0.0017 17.8 0.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Pkinase PF00069.20 CEH15327.1 - 4.5e-71 239.0 0.0 4.5e-71 239.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15327.1 - 1.8e-35 122.3 0.0 3.2e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH15327.1 - 1.2e-05 24.4 3.0 0.7 8.7 0.0 4.0 4 0 0 4 4 4 3 Kinase-like APH PF01636.18 CEH15327.1 - 0.003 17.3 4.4 1.1 8.9 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CEH15327.1 - 0.081 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Spore_coat_CotO PF14153.1 CEH15327.1 - 8.8 5.7 14.6 0.25 10.7 4.5 2.1 2 0 0 2 2 2 0 Spore coat protein CotO DHDPS PF00701.17 CEH15328.1 - 2.1e-41 141.4 0.0 2.5e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HORMA PF02301.13 CEH15330.1 - 1e-40 139.4 0.0 1.1e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 HORMA domain CN_hydrolase PF00795.17 CEH15331.1 - 5.4e-22 78.0 0.0 9.8e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_1 PF00076.17 CEH15331.1 - 2.4e-19 68.6 0.0 3.9e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH15331.1 - 9.6e-16 57.5 0.0 1.6e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH15331.1 - 1.5e-09 37.5 0.0 2.7e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEH15331.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif ICMT PF04140.9 CEH15332.1 - 9e-27 93.1 0.6 2.6e-26 91.6 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CEH15332.1 - 1.5e-12 47.5 0.5 1.5e-12 47.5 0.3 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 CEH15332.1 - 0.0055 16.0 3.0 0.0085 15.4 1.7 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 CEH15332.1 - 0.03 12.8 0.2 0.045 12.2 0.1 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.6 CEH15332.1 - 0.18 11.2 11.1 0.65 9.3 7.7 1.9 1 1 1 2 2 2 0 NnrU protein ABC_membrane PF00664.18 CEH15333.1 - 2.9e-70 236.8 26.7 1.5e-38 132.8 8.7 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEH15333.1 - 5.1e-50 169.3 0.1 8.8e-31 107.0 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CEH15333.1 - 5.3e-08 32.3 0.0 0.0017 17.6 0.1 3.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CEH15333.1 - 6.9e-05 22.9 5.1 0.004 17.1 0.4 3.0 3 0 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.4 CEH15333.1 - 0.00025 19.7 0.1 0.00092 17.9 0.1 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_21 PF13304.1 CEH15333.1 - 0.00076 19.5 0.0 0.88 9.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 CEH15333.1 - 0.0041 17.0 0.1 0.4 10.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CEH15333.1 - 0.0075 16.7 0.5 5.2 7.5 0.1 3.3 3 0 0 3 3 3 1 Miro-like protein AAA_25 PF13481.1 CEH15333.1 - 0.011 15.1 0.5 0.75 9.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 CEH15333.1 - 0.023 14.1 1.6 9.1 5.6 0.0 3.1 2 1 0 3 3 3 0 AAA-like domain DUF258 PF03193.11 CEH15333.1 - 0.026 13.7 0.1 6.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CEH15333.1 - 0.035 13.9 3.5 0.66 9.7 0.0 2.8 3 0 0 3 3 3 0 Dynamin family DUF87 PF01935.12 CEH15333.1 - 0.036 13.8 1.1 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_29 PF13555.1 CEH15333.1 - 0.039 13.4 0.5 2.8 7.5 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain GMC_oxred_N PF00732.14 CEH15334.1 - 4.2e-42 144.3 0.8 5.3e-42 143.9 0.1 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CEH15334.1 - 4.8e-23 82.0 3.6 1.1e-22 80.9 0.3 2.4 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CEH15334.1 - 9e-08 31.3 2.4 1.6e-05 23.9 0.7 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 CEH15334.1 - 5.2e-07 29.7 0.8 6.7e-05 22.8 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEH15334.1 - 1e-05 24.8 0.6 4.5e-05 22.6 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CEH15334.1 - 1.2e-05 24.4 3.4 0.00065 18.6 1.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEH15334.1 - 7.3e-05 22.7 0.9 0.00025 21.0 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CEH15334.1 - 0.0005 19.2 0.4 0.001 18.2 0.3 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 CEH15334.1 - 0.0012 17.4 0.7 0.0081 14.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 CEH15334.1 - 0.018 14.1 1.4 0.031 13.3 0.9 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 CEH15334.1 - 0.11 11.2 0.2 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Abhydrolase_5 PF12695.2 CEH15334.1 - 0.13 12.0 1.7 0.46 10.2 0.8 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family ThiF PF00899.16 CEH15334.1 - 0.19 11.5 1.2 0.43 10.3 0.9 1.5 1 0 0 1 1 1 0 ThiF family AA_permease PF00324.16 CEH15335.1 - 2.5e-120 402.0 24.5 3.3e-120 401.6 17.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEH15335.1 - 5.7e-35 120.6 26.4 7.3e-35 120.3 18.3 1.1 1 0 0 1 1 1 1 Amino acid permease Nop16 PF09420.5 CEH15336.1 - 2.2e-40 138.4 0.1 4.1e-40 137.5 0.1 1.4 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 XAP5 PF04921.9 CEH15338.1 - 3.3e-89 298.5 9.1 3.3e-89 298.5 6.3 2.4 1 1 0 2 2 2 1 XAP5, circadian clock regulator MAM33 PF02330.11 CEH15338.1 - 0.012 15.4 1.1 0.023 14.4 0.8 1.6 1 0 0 1 1 1 0 Mitochondrial glycoprotein LytR_C PF13399.1 CEH15338.1 - 1 9.8 3.5 2.5 8.5 0.5 2.2 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Arf PF00025.16 CEH15339.1 - 2.6e-36 124.5 0.0 7.3e-26 90.4 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 CEH15339.1 - 3.3e-13 49.3 0.0 1.2e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CEH15339.1 - 9.8e-09 35.7 0.0 2.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CEH15339.1 - 2.3e-07 30.2 0.0 3.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CEH15339.1 - 9.1e-07 28.2 0.0 9.1e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CEH15339.1 - 6.4e-06 25.0 0.0 9.3e-06 24.5 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 CEH15339.1 - 5.9e-05 22.9 0.0 7.2e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CEH15339.1 - 0.031 14.1 0.0 1.1 9.0 0.2 2.2 1 1 1 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 CEH15339.1 - 0.097 12.0 0.1 4.3 6.7 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ABC2_membrane PF01061.19 CEH15340.1 - 3.9e-31 107.8 22.1 3.9e-31 107.8 15.3 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CEH15340.1 - 2.8e-26 92.4 0.0 4.3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 CEH15340.1 - 8.3e-12 44.7 16.3 1.5e-11 43.9 11.3 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 CEH15340.1 - 1.3e-05 25.2 0.1 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain hEGF PF12661.2 CEH15340.1 - 2.2e-05 24.2 24.3 0.052 13.6 0.8 4.7 4 0 0 4 4 4 3 Human growth factor-like EGF AAA_29 PF13555.1 CEH15340.1 - 0.00057 19.3 0.1 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CEH15340.1 - 0.0014 17.8 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CEH15340.1 - 0.0037 16.6 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEH15340.1 - 0.007 17.1 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEH15340.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CEH15340.1 - 0.062 13.6 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 CEH15340.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.1 CEH15340.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 CEH15340.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CEH15340.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 CEH15340.1 - 0.23 11.3 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 CEH15340.1 - 0.29 10.9 0.1 0.56 9.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_23 PF13476.1 CEH15340.1 - 0.29 11.4 0.0 0.47 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.19 CEH15340.1 - 0.58 10.1 32.1 0.3 11.0 0.6 4.0 4 0 0 4 4 3 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 CEH15340.1 - 9.1 6.5 28.2 5.7 7.1 7.8 4.0 3 0 0 3 3 3 0 EGF-like domain IBN_N PF03810.14 CEH15341.1 - 8.9e-07 28.7 1.0 3e-05 23.8 0.1 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 CEH15341.1 - 0.00027 21.1 2.5 0.024 14.8 0.1 3.6 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 CEH15341.1 - 0.016 15.2 0.6 0.19 11.8 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.1 CEH15341.1 - 0.04 14.4 4.2 0.18 12.3 0.1 4.1 4 0 0 4 4 4 0 HEAT-like repeat Xpo1 PF08389.7 CEH15341.1 - 0.068 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Exportin 1-like protein Peptidase_A22B PF04258.8 CEH15343.1 - 4.7e-77 259.3 2.4 1.9e-45 155.6 0.1 2.1 1 1 1 2 2 2 2 Signal peptide peptidase DUF1119 PF06550.6 CEH15343.1 - 5.6e-07 28.9 1.9 6.2e-05 22.2 0.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1119) SMC_N PF02463.14 CEH15344.1 - 3e-65 219.5 2.1 4.3e-65 219.0 1.4 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CEH15344.1 - 2.3e-30 105.0 0.1 2.3e-30 105.0 0.1 2.4 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CEH15344.1 - 1.5e-15 57.9 8.1 6.5e-08 32.8 0.3 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CEH15344.1 - 5.5e-12 46.4 33.9 5.5e-12 46.4 23.5 5.9 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CEH15344.1 - 0.0026 17.2 0.0 0.0086 15.5 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CEH15344.1 - 0.69 10.2 0.0 0.69 10.2 0.0 5.8 4 2 0 4 4 4 0 ABC transporter AFG1_ATPase PF03969.11 CEH15346.1 - 2.8e-38 131.6 0.1 1.3e-34 119.6 0.0 2.9 2 1 0 2 2 2 2 AFG1-like ATPase LIME1 PF15332.1 CEH15346.1 - 0.011 15.0 0.2 0.21 10.8 0.0 2.2 2 0 0 2 2 2 0 Lck-interacting transmembrane adapter 1 EMP24_GP25L PF01105.19 CEH15347.1 - 1.7e-39 135.4 0.2 1.3e-27 96.6 0.0 2.2 2 0 0 2 2 2 2 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.13 CEH15348.1 - 8.4e-24 83.9 4.0 4.9e-17 62.1 0.3 2.4 1 1 1 2 2 2 2 RanBP1 domain WH1 PF00568.18 CEH15348.1 - 0.058 13.1 0.3 5.9 6.6 0.0 2.1 2 0 0 2 2 2 0 WH1 domain D5_N PF08706.6 CEH15348.1 - 0.23 11.5 2.5 0.39 10.7 1.7 1.4 1 1 0 1 1 1 0 D5 N terminal like CPSF100_C PF13299.1 CEH15349.1 - 9.6e-20 71.3 0.3 3.9e-19 69.4 0.0 2.1 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CEH15349.1 - 1.3e-15 57.4 0.0 3.1e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 CEH15349.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Myosin_HC-like PF07058.6 CEH15349.1 - 0.015 14.3 0.2 0.045 12.8 0.0 1.8 2 0 0 2 2 2 0 Myosin II heavy chain-like Hist_deacetyl PF00850.14 CEH15350.1 - 3.4e-80 269.6 0.0 4.6e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain zf-MYND PF01753.13 CEH15351.1 - 0.032 14.0 3.4 0.06 13.2 2.4 1.4 1 0 0 1 1 1 0 MYND finger DivIC PF04977.10 CEH15351.1 - 0.16 11.4 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Corona_nucleoca PF00937.13 CEH15351.1 - 0.87 8.4 6.5 1.2 8.0 4.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Atg14 PF10186.4 CEH15351.1 - 1.2 8.0 9.5 0.046 12.6 0.9 2.3 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Atg14 PF10186.4 CEH15352.1 - 3.6e-08 32.7 0.0 5.4e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Sugar_tr PF00083.19 CEH15356.1 - 2.1e-94 316.6 10.9 2.5e-94 316.4 7.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH15356.1 - 7.5e-23 80.8 22.4 1.6e-22 79.7 15.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily JSRP PF15312.1 CEH15356.1 - 0.43 10.5 1.9 5 7.1 0.3 2.5 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Herpes_UL56 PF04534.7 CEH15357.1 - 0.0041 16.8 0.4 0.0041 16.8 0.2 2.4 2 0 0 2 2 2 1 Herpesvirus UL56 protein Pyridox_oxidase PF01243.15 CEH15357.1 - 0.097 12.6 0.0 2.2 8.3 0.0 2.8 3 0 0 3 3 3 0 Pyridoxamine 5'-phosphate oxidase Abhydrolase_3 PF07859.8 CEH15358.1 - 1.7e-33 115.9 0.0 4.6e-33 114.5 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CEH15358.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ribonuc_L-PSP PF01042.16 CEH15359.1 - 2e-29 101.8 2.3 2.3e-27 95.1 1.6 2.0 1 1 0 1 1 1 1 Endoribonuclease L-PSP adh_short_C2 PF13561.1 CEH15360.1 - 1.7e-28 100.0 0.1 2.3e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEH15360.1 - 8.1e-28 97.4 0.1 1.4e-27 96.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH15360.1 - 1.1e-12 48.0 0.1 1.8e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CEH15360.1 - 0.0076 15.7 0.2 0.037 13.4 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CEH15360.1 - 0.017 13.9 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein His_biosynth PF00977.16 CEH15360.1 - 0.058 12.6 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Vps55 PF04133.9 CEH15361.1 - 1.5e-42 144.1 5.1 1.7e-42 143.9 3.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF681 PF05080.7 CEH15361.1 - 0.074 13.4 0.1 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF681) Mito_morph_reg PF14972.1 CEH15361.1 - 0.14 11.5 0.5 0.22 10.9 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator DUF2668 PF10873.3 CEH15361.1 - 0.24 11.5 1.9 0.26 11.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Peptidase_C12 PF01088.16 CEH15363.1 - 9.5e-52 175.2 0.1 1.1e-50 171.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 AMP-binding PF00501.23 CEH15366.1 - 5.7e-71 239.1 0.0 2.3e-43 148.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CEH15366.1 - 1.8e-10 41.5 0.1 3.2e-09 37.5 0.0 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain TFIIE-A_C-term PF11521.3 CEH15366.1 - 0.13 12.2 4.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Zip PF02535.17 CEH15367.1 - 3.3e-55 187.3 9.2 3.8e-55 187.1 6.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Strabismus PF06638.6 CEH15368.1 - 0.024 12.9 0.0 0.026 12.8 0.0 1.1 1 0 0 1 1 1 0 Strabismus protein AbbA_antirepres PF14156.1 CEH15368.1 - 0.062 12.9 0.3 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 Antirepressor AbbA ADK PF00406.17 CEH15370.1 - 1.9e-27 96.0 0.0 4.7e-17 62.2 0.0 2.3 1 1 1 2 2 2 2 Adenylate kinase AAA_18 PF13238.1 CEH15370.1 - 0.00013 22.2 0.0 0.00039 20.7 0.0 1.7 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 CEH15370.1 - 0.067 12.5 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase MOZ_SAS PF01853.13 CEH15372.1 - 1.8e-84 281.6 0.1 2.5e-84 281.2 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_1 PF00583.19 CEH15372.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2 PF00096.21 CEH15372.1 - 0.51 10.7 2.4 1.3 9.4 1.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.2 CEH15372.1 - 4.7 7.5 5.5 6.4 7.1 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CobN-Mg_chel PF02514.11 CEH15373.1 - 0.052 10.9 0.0 0.061 10.7 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase CENP-P PF13096.1 CEH15377.1 - 0.0016 17.7 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P End3 PF12761.2 CEH15377.1 - 0.039 13.5 4.6 0.064 12.8 3.2 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 ATG16 PF08614.6 CEH15377.1 - 0.061 13.1 15.0 0.064 13.0 6.3 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3678 PF12435.3 CEH15377.1 - 0.12 11.9 0.1 0.12 11.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3678) FadA PF09403.5 CEH15377.1 - 0.19 11.7 3.6 0.39 10.7 2.5 1.5 1 0 0 1 1 1 0 Adhesion protein FadA Mnd1 PF03962.10 CEH15377.1 - 2.2 7.9 6.3 4.3 6.9 4.3 1.4 1 0 0 1 1 1 0 Mnd1 family Herpes_BLLF1 PF05109.8 CEH15377.1 - 5.4 4.8 10.4 6.1 4.6 7.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF4407 PF14362.1 CEH15377.1 - 5.9 5.7 11.5 1.2 8.0 5.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IncA PF04156.9 CEH15377.1 - 8.3 5.9 12.2 5.1 6.6 5.2 2.5 2 1 0 2 2 2 0 IncA protein RTA1 PF04479.8 CEH15378.1 - 1.3e-42 145.8 2.8 2e-42 145.2 1.9 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1469 PF07332.6 CEH15378.1 - 0.01 15.5 1.7 0.01 15.5 1.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) DUF4389 PF14333.1 CEH15378.1 - 0.11 12.2 1.4 0.56 9.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) adh_short PF00106.20 CEH15379.1 - 3.1e-16 59.7 1.0 5.6e-16 58.8 0.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH15379.1 - 5.3e-11 42.7 0.0 6.9e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CEH15379.1 - 1.1e-08 34.7 0.0 2.2e-08 33.8 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEH15379.1 - 1.5e-08 34.8 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CEH15379.1 - 5.4e-07 29.4 0.3 7.1e-07 29.0 0.2 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 CEH15379.1 - 0.013 14.2 0.1 0.016 13.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GlutR_dimer PF00745.15 CEH15379.1 - 0.068 13.1 0.2 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.12 CEH15379.1 - 0.079 13.3 0.2 0.48 10.8 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pep3_Vps18 PF05131.9 CEH15381.1 - 4e-43 146.3 0.0 7.8e-43 145.4 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CEH15381.1 - 1.3e-09 37.8 0.0 1.1e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.4 CEH15381.1 - 3e-05 24.1 0.0 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 CEH15381.1 - 0.00012 21.8 2.3 0.00033 20.4 1.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CEH15381.1 - 0.011 15.4 1.8 0.025 14.2 1.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF2175 PF09943.4 CEH15381.1 - 0.023 14.7 0.1 0.072 13.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.1 CEH15381.1 - 0.14 12.1 1.7 0.36 10.9 1.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH15381.1 - 0.31 10.7 1.5 0.7 9.5 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.14 CEH15381.1 - 0.61 10.5 29.7 0.065 13.6 1.8 4.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein BCDHK_Adom3 PF10436.4 CEH15382.1 - 2.5e-42 144.1 0.1 3.7e-42 143.6 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CEH15382.1 - 0.00014 21.4 0.1 0.0003 20.4 0.1 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PCNP PF15473.1 CEH15383.1 - 0.092 13.0 1.2 0.16 12.2 0.2 1.8 1 1 1 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family Pyr_redox_2 PF07992.9 CEH15384.1 - 6.5e-28 97.9 0.0 1.4e-27 96.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEH15384.1 - 2.6e-10 40.5 3.7 2.1e-07 31.2 0.2 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CEH15384.1 - 0.00013 22.0 0.3 0.0029 17.6 0.1 3.0 3 2 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CEH15384.1 - 0.04 12.7 1.7 2.4 6.9 0.2 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A RVT_1 PF00078.22 CEH15386.1 - 1.8e-23 83.0 0.0 3.3e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CEH15386.1 - 0.014 14.9 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Toxin_1 PF00087.16 CEH15388.1 - 0.09 13.1 1.0 0.12 12.7 0.7 1.5 1 1 0 1 1 1 0 Snake toxin Glyco_hydro_11 PF00457.12 CEH15390.1 - 3.4e-35 121.0 1.9 1e-34 119.4 1.4 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 OTU PF02338.14 CEH15393.1 - 1.2e-17 64.6 0.1 2.5e-17 63.5 0.0 1.5 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CEH15393.1 - 0.11 11.7 0.0 15 4.8 0.0 2.2 1 1 1 2 2 2 0 Peptidase C65 Otubain ATP-synt_D PF01813.12 CEH15394.1 - 1.8e-55 187.5 6.9 1.2e-28 100.0 0.8 2.2 1 1 1 2 2 2 2 ATP synthase subunit D MT PF12777.2 CEH15394.1 - 0.03 13.0 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor IncA PF04156.9 CEH15395.1 - 0.033 13.7 0.5 0.064 12.8 0.4 1.4 1 0 0 1 1 1 0 IncA protein Glycophorin_A PF01102.13 CEH15396.1 - 0.083 12.6 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycophorin A Lactamase_B_2 PF12706.2 CEH15397.1 - 1e-07 31.7 0.1 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 CEH15397.1 - 0.0079 16.2 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Homeobox_KN PF05920.6 CEH15398.1 - 2.3e-16 59.2 0.2 2.3e-16 59.2 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CEH15398.1 - 4.4e-05 23.0 0.0 0.00013 21.5 0.0 1.7 2 0 0 2 2 2 1 Homeobox domain DUF3554 PF12074.3 CEH15398.1 - 0.054 12.9 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3554) Eaf7 PF07904.8 CEH15400.1 - 0.0011 18.8 0.1 0.0011 18.8 0.1 3.5 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 SDA1 PF05285.7 CEH15400.1 - 7.6 5.7 50.3 0.37 10.0 6.6 2.8 1 1 1 2 2 2 0 SDA1 Dioxygenase_C PF00775.16 CEH15402.1 - 1.9e-10 40.2 1.0 2.8e-08 33.2 0.7 2.5 1 1 0 1 1 1 1 Dioxygenase LRR_4 PF12799.2 CEH15404.1 - 9.2e-05 21.9 0.7 0.0084 15.7 0.0 3.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEH15404.1 - 0.011 15.6 0.5 12 6.3 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 CEH15404.1 - 0.24 11.7 4.9 22 5.8 0.0 4.1 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 CEH15404.1 - 0.29 11.3 4.8 7.7 6.9 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Cgr1 PF03879.9 CEH15405.1 - 5.4e-26 90.9 16.1 5.9e-26 90.7 11.2 1.0 1 0 0 1 1 1 1 Cgr1 family CAF-1_p150 PF11600.3 CEH15405.1 - 0.019 14.3 15.3 0.025 13.9 10.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Relaxase PF03432.9 CEH15405.1 - 0.086 12.2 5.6 0.093 12.1 3.9 1.0 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain SR-25 PF10500.4 CEH15405.1 - 0.12 11.8 18.4 0.24 10.8 12.8 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CytochromB561_N PF09786.4 CEH15405.1 - 0.12 10.7 4.2 0.14 10.6 2.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal PTPlike_phytase PF14566.1 CEH15405.1 - 0.32 11.0 3.7 0.39 10.7 2.5 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Hamartin PF04388.7 CEH15405.1 - 0.61 8.7 5.8 0.67 8.5 4.0 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4407 PF14362.1 CEH15405.1 - 0.87 8.4 6.3 0.93 8.3 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.9 CEH15405.1 - 1.1 9.1 9.4 1.5 8.7 6.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.4 CEH15405.1 - 1.4 7.7 12.8 2 7.3 8.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RR_TM4-6 PF06459.7 CEH15405.1 - 1.7 8.4 7.9 2.1 8.1 5.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATAD4 PF15321.1 CEH15405.1 - 1.7 9.6 10.8 0.35 11.9 4.9 1.7 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Hex_IIIa PF02455.11 CEH15405.1 - 3.2 6.3 7.5 3.6 6.1 5.2 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DDRGK PF09756.4 CEH15405.1 - 3.9 6.8 16.5 4.8 6.5 11.4 1.1 1 0 0 1 1 1 0 DDRGK domain Corona_nucleoca PF00937.13 CEH15405.1 - 6.2 5.6 14.4 7.3 5.4 10.0 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FHA PF00498.21 CEH15406.1 - 0.0025 17.8 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain TPR_1 PF00515.23 CEH15407.1 - 3.6e-13 48.5 0.2 0.25 11.0 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEH15407.1 - 5.5e-08 33.2 5.1 5.5e-06 26.8 1.3 12.3 11 4 2 13 13 12 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEH15407.1 - 7.6e-07 28.5 43.7 0.016 15.1 0.0 12.4 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_11 PF13414.1 CEH15407.1 - 2.7e-06 26.9 36.4 0.0013 18.3 0.1 10.0 11 2 2 13 13 13 3 TPR repeat TPR_17 PF13431.1 CEH15407.1 - 8.7e-05 22.4 3.5 38 4.8 0.0 7.8 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEH15407.1 - 0.00012 21.9 0.8 0.0014 18.5 0.2 11.8 10 4 3 14 14 14 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH15407.1 - 0.00028 21.2 64.9 0.14 12.8 0.0 14.8 12 4 3 15 15 15 3 Tetratricopeptide repeat TPR_8 PF13181.1 CEH15407.1 - 0.00038 20.0 0.1 1.4e+02 2.6 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Apc3 PF12895.2 CEH15407.1 - 0.0011 19.0 9.7 1.2 9.3 0.0 6.8 7 1 0 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CEH15407.1 - 0.074 12.8 18.8 19 5.3 0.1 8.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.1 CEH15407.1 - 0.28 11.1 0.0 0.14 12.1 0.2 11.5 14 1 0 14 14 13 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEH15407.1 - 1.6 9.3 23.6 33 5.2 0.1 9.5 11 0 0 11 11 9 0 Tetratricopeptide repeat SH3_1 PF00018.23 CEH15408.1 - 7.4e-05 22.0 0.1 0.00022 20.5 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CEH15408.1 - 0.0005 19.6 0.1 0.0029 17.1 0.1 2.1 1 1 0 1 1 1 1 Variant SH3 domain Abhydrolase_6 PF12697.2 CEH15409.1 - 2.3e-14 53.8 0.0 3.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH15409.1 - 1e-09 38.3 0.0 1.8e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CEH15409.1 - 8.7e-05 22.0 0.0 0.00015 21.2 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 CEH15409.1 - 0.0044 16.2 0.0 0.09 11.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CEH15409.1 - 0.062 12.8 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M50B PF13398.1 CEH15410.1 - 3.4e-53 180.0 19.4 4.1e-53 179.7 13.4 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M41 PF01434.13 CEH15410.1 - 0.18 11.2 0.1 0.26 10.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M41 Peptidase_M50 PF02163.17 CEH15410.1 - 0.19 10.6 0.0 0.19 10.6 0.0 2.7 2 1 1 3 3 3 0 Peptidase family M50 DUF3040 PF11239.3 CEH15410.1 - 3.8 7.6 10.5 24 5.0 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) ELFV_dehydrog PF00208.16 CEH15411.1 - 5.6e-50 170.2 0.0 7.8e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CEH15411.1 - 1.9e-28 98.5 0.1 2.6e-19 68.2 0.0 2.9 2 1 1 3 3 3 3 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 CEH15411.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain MT-A70 PF05063.9 CEH15412.1 - 1.4e-50 171.2 0.0 3.3e-33 114.7 0.0 2.2 2 0 0 2 2 2 2 MT-A70 DUF2029 PF09594.5 CEH15415.1 - 0.036 13.5 0.1 0.063 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) Glyco_hydro_17 PF00332.13 CEH15416.1 - 0.0077 15.3 1.7 1.4 7.8 0.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 MT0933_antitox PF14013.1 CEH15417.1 - 7 6.8 6.9 1.1e+02 2.9 3.2 2.6 2 1 0 2 2 2 0 MT0933-like antitoxin protein VTC PF09359.5 CEH15418.1 - 1.7e-100 335.6 0.0 3.3e-100 334.7 0.0 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CEH15418.1 - 2.5e-31 109.4 17.5 4.4e-31 108.6 5.8 3.4 2 2 0 2 2 2 1 SPX domain DUF202 PF02656.10 CEH15418.1 - 1.2e-12 47.8 0.7 2.5e-12 46.8 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) IATP PF04568.7 CEH15418.1 - 0.19 11.7 3.3 4.8 7.2 0.0 3.3 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Clc-like PF07062.7 CEH15418.1 - 0.51 9.5 1.8 0.93 8.6 1.2 1.3 1 0 0 1 1 1 0 Clc-like DUF1154 PF06631.6 CEH15418.1 - 0.74 9.5 6.6 14 5.4 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1154) Mob1_phocein PF03637.12 CEH15419.1 - 8.1e-23 80.9 0.0 2.2e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 Mob1/phocein family Daxx PF03344.10 CEH15419.1 - 0.99 7.8 10.9 1.6 7.1 7.6 1.2 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 CEH15419.1 - 8.7 6.3 11.5 23 4.9 8.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) HSP70 PF00012.15 CEH15420.1 - 2.9e-153 510.9 0.0 3.6e-153 510.6 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEH15420.1 - 8.9e-10 37.6 0.0 1.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein CsbD PF05532.7 CEH15422.1 - 0.014 15.0 2.3 0.086 12.5 0.2 2.4 2 0 0 2 2 2 0 CsbD-like Mito_carr PF00153.22 CEH15423.1 - 9.7e-19 66.8 0.0 8.9e-06 25.3 0.0 5.5 5 1 0 5 5 5 4 Mitochondrial carrier protein Sensor PF13796.1 CEH15423.1 - 0.0015 18.1 0.6 0.019 14.5 0.0 2.7 1 1 1 2 2 2 1 Putative sensor START PF01852.14 CEH15425.1 - 1.9e-06 27.3 0.0 3.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 START domain FAM196 PF15265.1 CEH15426.1 - 7.9 5.5 14.4 10 5.2 10.0 1.1 1 0 0 1 1 1 0 FAM196 family Tannase PF07519.6 CEH15431.1 - 2.1e-77 260.8 1.7 1.6e-76 257.9 1.4 2.1 2 1 0 2 2 2 1 Tannase and feruloyl esterase Kinesin PF00225.18 CEH15432.1 - 2.7e-111 371.4 1.7 3.2e-111 371.2 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF869 PF05911.6 CEH15432.1 - 0.0016 16.8 10.1 0.0016 16.8 7.0 2.6 1 1 0 2 2 2 1 Plant protein of unknown function (DUF869) EMP24_GP25L PF01105.19 CEH15432.1 - 0.01 15.5 0.5 0.01 15.5 0.3 3.8 4 1 0 4 4 4 0 emp24/gp25L/p24 family/GOLD Filament PF00038.16 CEH15432.1 - 0.088 12.2 64.1 0.011 15.2 25.9 3.8 2 1 1 3 3 3 0 Intermediate filament protein GAS PF13851.1 CEH15432.1 - 1.6 7.9 72.8 0.21 10.7 7.1 5.6 4 2 1 5 5 5 0 Growth-arrest specific micro-tubule binding Foie-gras_1 PF11817.3 CEH15433.1 - 8.5e-23 81.1 0.1 1.6e-22 80.2 0.1 1.5 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.7 CEH15433.1 - 5.3e-20 71.2 0.0 9.6e-12 43.9 0.0 2.1 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi TPR_6 PF13174.1 CEH15433.1 - 0.014 15.8 0.0 0.079 13.4 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat MT-A70 PF05063.9 CEH15434.1 - 4e-10 39.5 0.7 0.012 15.1 0.0 4.1 2 1 1 4 4 4 3 MT-A70 Methyltransf_26 PF13659.1 CEH15434.1 - 0.054 13.5 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain SOG2 PF10428.4 CEH15435.1 - 5.1e-34 117.6 1.5 5.1e-34 117.6 1.0 4.9 3 2 1 4 4 4 2 RAM signalling pathway protein LRR_4 PF12799.2 CEH15435.1 - 1.6e-16 59.4 2.0 5.9e-07 28.9 0.0 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEH15435.1 - 1.5e-11 43.8 0.5 2.7e-06 27.0 0.1 2.9 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CEH15435.1 - 9.2e-08 31.1 0.2 4.2 7.7 0.0 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CEH15435.1 - 0.022 14.8 4.1 30 5.4 0.1 5.3 5 1 1 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 CEH15435.1 - 0.043 13.8 0.8 32 4.9 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat LRR_9 PF14580.1 CEH15435.1 - 0.36 10.3 0.4 0.73 9.3 0.2 1.5 1 1 0 1 1 1 0 Leucine-rich repeat LRR_4 PF12799.2 CEH15437.1 - 1.5e-19 69.1 12.2 5.1e-06 25.9 3.2 6.9 5 1 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEH15437.1 - 1.6e-13 50.1 12.9 1.1e-10 41.0 2.1 4.8 5 1 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 CEH15437.1 - 4.4e-12 44.2 9.8 0.72 10.1 0.1 8.8 7 1 1 8 8 8 4 Leucine Rich Repeat LRR_9 PF14580.1 CEH15437.1 - 1.5e-06 27.8 0.2 0.0016 18.0 0.2 2.6 2 1 0 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 CEH15437.1 - 5.3e-05 22.7 13.3 28 5.5 0.0 8.4 9 0 0 9 9 9 0 Leucine rich repeat LRR_6 PF13516.1 CEH15437.1 - 0.045 13.8 11.4 7.6 6.9 0.1 7.0 8 0 0 8 8 8 0 Leucine Rich repeat TBCC PF07986.7 CEH15438.1 - 8.2e-15 54.2 0.1 1.5e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C GST_N_3 PF13417.1 CEH15439.1 - 7.9e-05 22.8 0.0 0.00038 20.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEH15439.1 - 0.019 14.9 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF1117 PF06547.7 CEH15439.1 - 0.026 14.6 0.0 0.076 13.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) Thioredoxin PF00085.15 CEH15440.1 - 2.6e-20 72.0 0.0 3.3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CEH15440.1 - 0.0019 18.3 0.1 0.024 14.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 CEH15440.1 - 0.0028 17.7 0.1 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 CEH15440.1 - 0.028 14.5 0.1 0.12 12.4 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin-like ACOX PF01756.14 CEH15441.1 - 9.4e-19 67.5 0.0 2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CEH15441.1 - 5.8e-17 62.1 0.3 6.1e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CEH15441.1 - 1.9e-10 40.0 0.8 4.5e-10 38.8 0.6 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Abhydro_lipase PF04083.11 CEH15442.1 - 2.4e-15 55.6 0.0 4.3e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CEH15442.1 - 2.6e-05 24.1 0.1 4.4e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH15442.1 - 0.00017 21.3 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH15442.1 - 0.0039 16.7 0.1 0.03 13.8 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold SIR2 PF02146.12 CEH15443.1 - 9.9e-54 181.7 0.0 1.4e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family UQ_con PF00179.21 CEH15443.1 - 3.9e-35 120.3 0.0 5.6e-19 67.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme OrfB_Zn_ribbon PF07282.6 CEH15443.1 - 0.12 12.0 2.1 0.13 11.8 0.5 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain SAICAR_synt PF01259.13 CEH15444.1 - 1.6e-77 259.9 0.0 1.2e-76 257.1 0.0 1.9 1 1 0 1 1 1 1 SAICAR synthetase SET PF00856.23 CEH15445.1 - 1.9e-08 34.8 0.1 1.1e-07 32.2 0.0 2.3 3 0 0 3 3 3 1 SET domain Rubis-subs-bind PF09273.6 CEH15445.1 - 1.1e-07 31.7 2.2 3.6e-07 30.1 1.2 2.1 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Dus PF01207.12 CEH15446.1 - 1.9e-46 158.3 0.1 2.7e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Pkinase PF00069.20 CEH15447.1 - 2.8e-66 223.3 0.0 3.9e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15447.1 - 6.4e-45 153.2 0.0 9.4e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH15447.1 - 2.2e-10 39.9 0.0 4.9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEH15447.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med10 PF09748.4 CEH15448.1 - 6e-16 58.4 0.0 8.1e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Linocin_M18 PF04454.7 CEH15448.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase EXS PF03124.9 CEH15449.1 - 3.9e-34 118.2 0.0 6.8e-34 117.4 0.0 1.3 1 1 0 1 1 1 1 EXS family EXS PF03124.9 CEH15450.1 - 1.3e-22 80.2 0.2 1.6e-22 80.0 0.1 1.1 1 0 0 1 1 1 1 EXS family Lactamase_B_2 PF12706.2 CEH15451.1 - 1.1e-26 93.6 0.3 1.3e-25 90.1 0.2 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CEH15451.1 - 4.3e-08 33.0 0.0 5.1e-06 26.2 0.0 3.1 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CEH15451.1 - 0.0018 17.9 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Cytochrome-c551 PF10643.4 CEH15452.1 - 0.096 11.9 0.5 0.15 11.3 0.3 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 V-ATPase_C PF03223.10 CEH15454.1 - 1.7e-106 356.3 0.0 1.9e-106 356.1 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Peroxin-13_N PF04088.8 CEH15455.1 - 3e-55 186.4 0.0 4.5e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 CEH15455.1 - 1.9e-12 46.4 0.0 3.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CEH15455.1 - 9.2e-12 44.3 0.1 1.5e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEH15455.1 - 1.4e-10 40.4 0.0 2.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Pex2_Pex12 PF04757.9 CEH15455.1 - 0.015 14.7 0.1 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region TFIIS_M PF07500.9 CEH15456.1 - 3.9e-28 97.8 0.0 7.6e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CEH15456.1 - 1.6e-17 62.8 7.3 2.6e-17 62.1 5.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CEH15456.1 - 3.4e-10 39.2 0.1 6.4e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 CEH15456.1 - 0.047 13.0 0.6 0.085 12.2 0.2 1.6 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain DUF1660 PF07874.6 CEH15456.1 - 0.053 13.8 0.6 0.084 13.1 0.1 1.6 1 1 0 1 1 1 0 Prophage protein (DUF1660) DUF3713 PF12506.3 CEH15456.1 - 0.098 12.7 0.8 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) UTP15_C PF09384.5 CEH15459.1 - 4.9e-35 120.4 0.0 7.6e-35 119.7 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CEH15459.1 - 4.9e-29 99.1 18.3 3.5e-09 36.2 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 CEH15459.1 - 1.1e-05 23.7 0.2 0.00019 19.7 0.0 2.5 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CEH15459.1 - 2.4e-05 22.8 0.2 0.0011 17.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 CEH15459.1 - 0.23 11.7 10.2 1.5 9.2 0.1 4.3 4 1 1 5 5 5 0 PQQ-like domain Fer2 PF00111.22 CEH15460.1 - 1.3e-11 44.0 0.2 2.4e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FlgD_ig PF13860.1 CEH15460.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain HIT PF01230.18 CEH15461.1 - 5.5e-25 87.7 0.3 7.8e-25 87.2 0.0 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 CEH15461.1 - 1.1e-14 54.6 0.0 1.5e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CEH15461.1 - 0.0052 16.4 0.1 0.0077 15.8 0.1 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pkinase PF00069.20 CEH15462.1 - 4.4e-24 85.0 0.0 2.8e-15 56.1 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15462.1 - 4e-13 49.0 0.0 2e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH15462.1 - 0.34 9.8 0.0 0.56 9.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like rRNA_processing PF08524.6 CEH15464.1 - 0.19 11.5 16.9 0.4 10.4 8.9 2.7 2 1 0 2 2 2 0 rRNA processing DUF4407 PF14362.1 CEH15464.1 - 1.4 7.7 6.5 1.7 7.4 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.17 CEH15466.1 - 1.2e-33 114.5 0.0 2.6e-20 71.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH15466.1 - 6.8e-22 77.2 0.0 7.9e-12 44.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH15466.1 - 3.8e-10 39.4 0.1 1.6e-08 34.2 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PfkB PF00294.19 CEH15467.1 - 3.3e-11 42.8 0.0 5.1e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase tRNA-synt_1b PF00579.20 CEH15468.1 - 3.2e-63 213.5 0.0 4.8e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) GCIP PF13324.1 CEH15469.1 - 0.0022 17.2 0.4 0.021 14.0 0.0 2.7 3 0 0 3 3 3 1 Grap2 and cyclin-D-interacting Ribosomal_S21e PF01249.13 CEH15470.1 - 2.3e-35 120.3 0.0 2.5e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SpoA PF01052.15 CEH15470.1 - 0.048 13.2 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) ADH_zinc_N PF00107.21 CEH15471.1 - 3.7e-29 100.8 0.2 5.7e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH15471.1 - 2e-13 50.0 0.1 1.5e-11 43.9 0.0 3.0 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CEH15471.1 - 9.5e-09 36.2 0.1 2.7e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 CEH15471.1 - 0.051 13.5 0.1 0.08 12.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain MIF4G PF02854.14 CEH15472.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain adh_short PF00106.20 CEH15475.1 - 4.5e-13 49.4 4.6 5.1e-07 29.7 2.4 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 CEH15475.1 - 4.3e-05 23.2 2.4 0.00017 21.2 1.7 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CEH15475.1 - 7.2e-05 22.6 0.4 0.00017 21.4 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CEH15475.1 - 0.0025 17.8 1.1 0.0092 16.0 0.5 1.9 1 1 1 2 2 2 1 NADH(P)-binding 3HCDH_N PF02737.13 CEH15475.1 - 0.0079 15.8 1.3 0.015 14.9 0.9 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_S10 PF00450.17 CEH15477.1 - 5.8e-106 355.1 0.0 7.2e-106 354.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CEH15477.1 - 0.0013 18.6 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family FlxA PF14282.1 CEH15478.1 - 0.027 14.4 0.8 0.027 14.4 0.6 2.2 3 0 0 3 3 3 0 FlxA-like protein Syntaxin PF00804.20 CEH15478.1 - 0.58 10.3 5.3 11 6.3 0.7 3.0 3 1 1 4 4 4 0 Syntaxin NDUF_B4 PF07225.7 CEH15479.1 - 3.6e-06 26.8 0.0 3.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DAP3 PF10236.4 CEH15480.1 - 2.4e-34 118.6 0.0 3.5e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CEH15480.1 - 0.00021 21.3 0.5 0.0004 20.4 0.4 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CEH15480.1 - 0.00066 19.3 0.1 0.0017 18.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 CEH15480.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase Ric8 PF10165.4 CEH15481.1 - 2e-77 260.9 0.0 3.4e-77 260.1 0.0 1.4 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn GATA PF00320.22 CEH15482.1 - 3e-17 61.6 1.1 6.4e-17 60.6 0.8 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 CEH15482.1 - 4.7e-13 48.4 2.8 8.4e-13 47.6 1.9 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Mannosyl_trans3 PF11051.3 CEH15483.1 - 5.7e-54 183.2 0.0 8.2e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative BSD PF03909.12 CEH15484.1 - 3.5e-18 65.1 0.3 4.8e-13 48.6 0.1 2.7 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 CEH15484.1 - 3.3e-07 29.8 1.4 4.2e-07 29.5 0.0 2.0 3 0 0 3 3 3 1 TFIIH p62 subunit, N-terminal domain Ribonuc_L-PSP PF01042.16 CEH15484.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Endoribonuclease L-PSP Mannosyl_trans3 PF11051.3 CEH15485.1 - 1.3e-30 106.6 0.0 9.3e-30 103.8 0.0 1.9 2 0 0 2 2 2 1 Mannosyltransferase putative EB PF01683.13 CEH15487.1 - 3.8e-06 26.8 56.5 0.0075 16.3 4.1 4.7 1 1 4 5 5 5 5 EB module YTV PF07639.6 CEH15487.1 - 0.0085 15.7 0.4 0.027 14.2 0.1 1.9 2 0 0 2 2 2 1 YTV UPF0506 PF11703.3 CEH15487.1 - 0.036 14.0 6.5 0.036 14.0 4.5 4.1 3 1 0 3 3 3 0 UPF0506 Nuc_sug_transp PF04142.10 CEH15488.1 - 7.2e-55 185.7 10.7 6.7e-36 123.6 1.4 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 CEH15488.1 - 7.5e-07 29.3 2.3 7.5e-07 29.3 1.6 2.9 3 0 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CEH15488.1 - 4.1e-05 23.6 1.3 4.1e-05 23.6 0.9 3.3 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 CEH15488.1 - 0.0065 16.1 17.2 0.02 14.5 0.5 2.6 2 0 0 2 2 2 2 Triose-phosphate Transporter family PrgI PF12666.2 CEH15488.1 - 1.4 9.1 5.4 25 5.1 1.0 2.8 2 0 0 2 2 2 0 PrgI family protein DUF1129 PF06570.6 CEH15488.1 - 7.7 5.7 7.5 0.53 9.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3184 PF11380.3 CEH15489.1 - 3.1e-06 25.4 0.1 0.039 11.8 0.0 3.9 3 1 1 4 4 4 3 Protein of unknown function (DUF3184) DUF3357 PF11837.3 CEH15489.1 - 0.018 14.8 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Glycos_transf_1 PF00534.15 CEH15490.1 - 7.7e-26 90.5 0.0 1.5e-25 89.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CEH15490.1 - 1.7e-06 28.2 0.0 4.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CEH15490.1 - 5.7e-06 26.5 0.0 0.00016 21.8 0.0 2.7 2 1 0 2 2 2 1 Glycosyl transferases group 1 DUF572 PF04502.8 CEH15492.1 - 0.71 9.0 9.8 1.7 7.7 6.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) GMC_oxred_C PF05199.8 CEH15493.1 - 1.3e-29 103.2 0.0 2e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CEH15493.1 - 1.4e-19 70.3 0.0 1.9e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Abhydrolase_3 PF07859.8 CEH15494.1 - 1.1e-11 44.7 0.4 2.3e-11 43.6 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH15494.1 - 1.8e-09 37.4 0.0 3.5e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEH15494.1 - 1.9e-07 30.5 0.0 0.00083 18.6 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family PucR PF07905.6 CEH15494.1 - 0.045 13.3 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Acyl-CoA_dh_1 PF00441.19 CEH15495.1 - 5.3e-11 42.8 2.5 4.5e-09 36.5 0.0 3.2 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEH15495.1 - 1e-06 28.1 0.2 2.3e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CEH15495.1 - 7e-05 23.3 0.2 0.00026 21.5 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF2422 PF10337.4 CEH15496.1 - 6.2e-43 147.2 0.1 6.2e-43 147.2 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CEH15496.1 - 1.5e-12 47.5 21.7 6e-12 45.6 11.8 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like SR-25 PF10500.4 CEH15496.1 - 0.025 14.0 3.9 0.044 13.2 2.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IFT43 PF15305.1 CEH15496.1 - 0.2 11.6 5.2 0.079 12.9 0.7 2.0 2 0 0 2 2 2 0 Intraflagellar transport protein 43 DUF1736 PF08409.6 CEH15496.1 - 0.6 9.7 2.7 0.31 10.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1736) MCPsignal PF00015.16 CEH15496.1 - 8.1 5.9 8.6 0.33 10.4 0.7 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FHA PF00498.21 CEH15497.1 - 7.6e-06 25.9 0.0 1.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain HTH_24 PF13412.1 CEH15497.1 - 0.24 10.7 0.5 0.59 9.5 0.4 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ATP-synt_C PF00137.16 CEH15498.1 - 2.2e-29 101.1 30.7 1.5e-17 63.2 8.9 2.4 2 0 0 2 2 2 2 ATP synthase subunit C DNA_methylase PF00145.12 CEH15499.1 - 2.1e-47 161.8 0.0 1.2e-46 159.4 0.0 1.9 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.5 CEH15499.1 - 0.017 14.7 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 CEH15499.1 - 0.028 13.7 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PAP2 PF01569.16 CEH15500.1 - 4.7e-16 58.6 5.7 4.7e-16 58.6 4.0 2.2 2 0 0 2 2 2 1 PAP2 superfamily DinB_2 PF12867.2 CEH15501.1 - 8.5e-06 26.1 0.9 1.6e-05 25.2 0.6 1.4 1 1 0 1 1 1 1 DinB superfamily DinB PF05163.7 CEH15501.1 - 0.0061 16.2 0.1 0.01 15.5 0.1 1.3 1 0 0 1 1 1 1 DinB family MDMPI_N PF11716.3 CEH15501.1 - 0.015 15.7 0.1 0.026 14.9 0.1 1.4 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Docking PF08990.6 CEH15501.1 - 0.023 13.9 0.2 0.04 13.1 0.2 1.4 1 0 0 1 1 1 0 Erythronolide synthase docking ABC_membrane PF00664.18 CEH15502.1 - 5.2e-93 311.4 23.7 4.7e-49 167.2 6.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEH15502.1 - 3e-70 234.8 0.1 1.4e-34 119.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CEH15502.1 - 7.3e-14 51.5 0.1 2.6e-05 23.5 0.6 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 CEH15502.1 - 2.7e-12 46.0 0.8 0.0003 19.5 0.0 3.7 4 0 0 4 4 4 3 Predicted ATPase of the ABC class AAA_21 PF13304.1 CEH15502.1 - 5.8e-11 42.8 0.0 0.0085 16.0 0.0 4.2 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 CEH15502.1 - 4.5e-08 32.4 0.8 0.00052 19.4 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CEH15502.1 - 1e-07 32.1 7.4 0.0027 17.6 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 CEH15502.1 - 3.3e-06 27.9 0.0 0.037 14.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CEH15502.1 - 8.4e-06 25.9 2.6 0.2 11.7 0.1 4.1 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CEH15502.1 - 4.8e-05 23.2 2.9 0.31 10.9 0.3 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 CEH15502.1 - 5.5e-05 22.4 0.0 0.077 12.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_19 PF13245.1 CEH15502.1 - 0.0003 20.4 0.1 0.76 9.5 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 CEH15502.1 - 0.00067 19.1 2.8 0.13 11.6 0.0 3.0 3 1 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 CEH15502.1 - 0.0012 17.9 0.0 0.5 9.4 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.12 CEH15502.1 - 0.0018 18.1 0.4 2.1 8.0 0.0 2.9 3 0 0 3 3 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 CEH15502.1 - 0.0026 18.1 0.3 0.49 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CEH15502.1 - 0.0033 17.3 0.0 1.8 8.4 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 CEH15502.1 - 0.0051 16.5 0.2 6.8 6.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CEH15502.1 - 0.0082 16.4 0.0 6.6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CEH15502.1 - 0.011 15.5 0.3 1.3 8.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 CEH15502.1 - 0.012 16.0 0.0 3.9 7.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 CEH15502.1 - 0.014 15.3 0.7 2.9 7.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 CEH15502.1 - 0.036 13.5 1.8 7.9 5.8 0.0 3.5 4 0 0 4 4 4 0 AAA-like domain G-alpha PF00503.15 CEH15502.1 - 0.048 12.3 3.4 0.51 8.9 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit PRK PF00485.13 CEH15502.1 - 0.067 12.7 0.0 8.5 5.8 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 CEH15502.1 - 0.89 8.5 0.0 3.8 6.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Nol1_Nop2_Fmu PF01189.12 CEH15503.1 - 2.4e-06 27.1 0.0 0.00088 18.7 0.0 2.4 2 0 0 2 2 2 2 NOL1/NOP2/sun family adh_short PF00106.20 CEH15506.1 - 1.1e-26 93.8 0.1 1.3e-26 93.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH15506.1 - 4.9e-25 88.6 0.0 6.2e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH15506.1 - 4.2e-09 36.3 0.0 5.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CEH15506.1 - 0.025 13.7 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Methyltransf_25 PF13649.1 CEH15510.1 - 0.02 15.2 0.1 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PIG-P PF08510.7 CEH15511.1 - 0.013 15.1 0.9 0.013 15.1 0.6 2.1 3 0 0 3 3 3 0 PIG-P PPR_2 PF13041.1 CEH15512.1 - 8.3e-28 96.1 0.0 1.2e-08 34.7 0.0 8.2 7 2 2 9 9 9 5 PPR repeat family PPR_3 PF13812.1 CEH15512.1 - 2.2e-20 71.1 17.8 0.005 17.0 0.0 13.0 14 0 0 14 14 14 5 Pentatricopeptide repeat domain PPR PF01535.15 CEH15512.1 - 3.1e-17 61.2 0.4 0.012 15.5 0.0 9.6 11 0 0 11 11 11 4 PPR repeat PPR_1 PF12854.2 CEH15512.1 - 1.9e-06 27.2 1.1 0.14 11.6 0.0 6.0 7 0 0 7 7 7 2 PPR repeat OMPdecase PF00215.19 CEH15513.1 - 1e-71 240.9 0.2 1.5e-71 240.3 0.2 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family ChaC PF04752.7 CEH15513.1 - 7.7e-48 162.7 0.0 1.3e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein DUF1754 PF08555.5 CEH15514.1 - 3.9e-06 27.3 0.9 3.9e-06 27.3 0.6 2.0 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) VPS11_C PF12451.3 CEH15514.1 - 0.068 13.0 2.0 0.11 12.3 1.4 1.5 1 1 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal DUF2317 PF10079.4 CEH15514.1 - 0.13 10.7 1.9 0.13 10.8 1.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) FH2 PF02181.18 CEH15517.1 - 1.3e-69 234.8 1.7 1.3e-69 234.8 1.2 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 CEH15517.1 - 1.3e-46 158.3 0.0 4.5e-46 156.5 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 CEH15517.1 - 1.2e-38 132.4 0.0 5.3e-38 130.4 0.0 2.1 1 1 0 1 1 1 1 Diaphanous FH3 Domain Rxt3 PF08642.5 CEH15517.1 - 0.22 11.7 1.9 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 KH_1 PF00013.24 CEH15518.1 - 1.5e-40 136.6 9.7 9.4e-16 57.2 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CEH15518.1 - 8.6e-31 105.0 15.7 2.9e-10 39.5 0.1 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CEH15518.1 - 3.2e-16 58.6 3.9 1.9e-05 24.0 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CEH15518.1 - 2e-05 24.1 2.3 0.64 9.6 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CEH15518.1 - 0.023 14.4 5.0 3 7.7 0.1 3.6 3 0 0 3 3 3 0 NusA-like KH domain MFS_1 PF07690.11 CEH15521.1 - 4.6e-32 111.1 39.9 4.6e-32 111.1 27.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CEH15521.1 - 1.2e-06 27.0 2.4 1.9e-06 26.4 1.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 CEH15521.1 - 0.0095 14.0 0.7 0.0095 14.0 0.5 1.9 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M16 PF00675.15 CEH15522.1 - 1.2e-54 184.0 0.2 2.3e-54 183.2 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CEH15522.1 - 2.5e-42 144.6 0.0 3.9e-40 137.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain Nop53 PF07767.6 CEH15523.1 - 1.2e-46 159.5 17.7 1.4e-46 159.2 12.3 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) RICH PF05062.7 CEH15523.1 - 0.027 14.5 1.4 0.075 13.1 1.0 1.7 1 0 0 1 1 1 0 RICH domain PDZ_2 PF13180.1 CEH15523.1 - 0.1 12.5 0.1 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain tRNA-synt_2b PF00587.20 CEH15524.1 - 1.5e-43 148.3 0.1 2.6e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEH15524.1 - 3.1e-17 62.2 0.0 7.5e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 CEH15524.1 - 1.8e-14 53.3 0.0 3.8e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 CEH15524.1 - 1.6e-10 40.6 0.0 3.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Metallophos PF00149.23 CEH15525.1 - 2.6e-31 108.6 0.9 7.3e-31 107.1 0.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2268 PF10026.4 CEH15525.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Siva PF05458.7 CEH15525.1 - 0.15 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) APS_kinase PF01583.15 CEH15526.1 - 3.3e-69 231.5 0.0 3.9e-69 231.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CEH15526.1 - 1.1e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CEH15526.1 - 1.5e-05 25.2 0.0 2.9e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEH15526.1 - 9.3e-05 23.2 0.0 0.00015 22.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CEH15526.1 - 0.0023 17.1 0.0 0.0026 17.0 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 CEH15526.1 - 0.0039 16.7 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CEH15526.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin Myb_DNA-binding PF00249.26 CEH15528.1 - 8e-32 109.0 9.0 1.5e-10 40.9 0.4 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH15528.1 - 4.9e-28 97.0 3.9 8.4e-14 51.4 0.3 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 CEH15528.1 - 0.00052 19.7 0.9 0.25 11.1 0.1 4.0 3 2 0 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.3 CEH15528.1 - 0.0073 16.1 3.0 0.49 10.3 0.4 2.6 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 CEH15528.1 - 0.042 13.9 8.1 3.2 7.9 1.4 3.5 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 CEH15528.1 - 0.14 12.4 7.2 1.6 9.0 0.2 2.8 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.1 CEH15528.1 - 5 7.0 11.0 42 4.1 0.5 4.7 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain DUF3511 PF12023.3 CEH15530.1 - 0.088 12.1 0.4 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3511) MFS_1 PF07690.11 CEH15531.1 - 1.3e-11 43.7 29.2 1.3e-11 43.7 20.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Lipase_3 PF01764.20 CEH15535.1 - 5.5e-23 81.1 0.0 7.4e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) TFIIS_M PF07500.9 CEH15536.1 - 5.5e-13 48.9 0.4 1.2e-12 47.8 0.3 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 CEH15536.1 - 2.4e-10 39.9 7.3 4e-10 39.2 5.1 1.4 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 CEH15536.1 - 6.6e-09 36.2 0.0 1.5e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 SPOC domain PHD_3 PF13922.1 CEH15536.1 - 0.088 13.0 0.1 0.43 10.8 0.1 2.2 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.1 CEH15536.1 - 0.5 9.7 2.9 0.95 8.8 2.0 1.5 1 0 0 1 1 1 0 PHD-finger CRAL_TRIO PF00650.15 CEH15537.1 - 2.9e-33 114.6 0.0 4.7e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEH15537.1 - 1.6e-11 44.1 0.2 1.6e-11 44.1 0.1 2.4 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CEH15537.1 - 1.1e-10 41.6 0.0 1.7e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF123 PF01986.11 CEH15540.1 - 0.089 12.9 0.3 0.18 11.9 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF123 DUF2638 PF10937.3 CEH15541.1 - 3.6e-14 53.7 0.5 4.4e-14 53.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Porin_3 PF01459.17 CEH15542.1 - 2.2e-72 243.6 0.3 2.5e-72 243.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin ETC_C1_NDUFA4 PF04800.7 CEH15543.1 - 9.5e-33 112.0 0.3 1.4e-32 111.4 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Zn_clus PF00172.13 CEH15544.1 - 6.9e-06 25.8 7.7 6.9e-06 25.8 5.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 CEH15544.1 - 0.00011 22.3 0.0 0.00031 20.9 0.0 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH15544.1 - 0.0011 19.1 1.5 0.0018 18.5 0.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger DUF1610 PF07754.6 CEH15544.1 - 3.5 7.8 9.3 0.047 13.8 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) RseC_MucC PF04246.7 CEH15544.1 - 4.4 6.8 7.7 6.2 6.3 0.2 2.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SET PF00856.23 CEH15546.1 - 1.4e-08 35.2 0.0 7.5e-07 29.5 0.0 2.9 3 0 0 3 3 3 1 SET domain HhH-GPD PF00730.20 CEH15547.1 - 1e-15 57.9 0.0 1.9e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CEH15547.1 - 3.5e-08 32.7 0.0 1.3e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif Ank_2 PF12796.2 CEH15548.1 - 2.2e-23 82.3 0.2 1.7e-10 41.0 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEH15548.1 - 5e-22 77.8 0.5 1.3e-12 47.8 0.1 4.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 CEH15548.1 - 1.2e-19 69.0 0.0 4.3e-08 32.5 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CEH15548.1 - 3e-17 61.0 0.3 3e-05 23.8 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CEH15548.1 - 3.8e-17 61.9 0.3 6.6e-08 32.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 CEH15548.1 - 1.6e-05 24.5 0.1 0.00032 20.3 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain DUF4286 PF14114.1 CEH15548.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) FAM104 PF15434.1 CEH15548.1 - 1.1 9.4 4.3 1.3 9.3 0.9 2.3 2 0 0 2 2 2 0 Family 104 Metallophos_2 PF12850.2 CEH15549.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GAF PF01590.21 CEH15552.1 - 1.4e-06 28.4 0.1 5.3e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 GAF domain Abhydrolase_3 PF07859.8 CEH15553.1 - 1.6e-29 102.9 0.4 7.5e-14 51.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF4202 PF13875.1 CEH15554.1 - 3.3e-56 189.8 0.0 5.6e-56 189.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Methyltransf_23 PF13489.1 CEH15554.1 - 3.1e-14 53.0 0.1 6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH15554.1 - 1e-11 45.1 0.0 3.7e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH15554.1 - 6.4e-09 36.1 0.0 2.3e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH15554.1 - 3.4e-08 33.7 0.0 4e-07 30.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH15554.1 - 4.9e-08 32.7 0.0 5.2e-07 29.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH15554.1 - 2.2e-07 31.4 0.1 2e-06 28.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH15554.1 - 0.00018 21.5 0.6 0.0034 17.3 0.4 2.7 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CEH15554.1 - 0.00071 18.6 0.0 0.06 12.3 0.0 2.3 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family HMG_box PF00505.14 CEH15554.1 - 0.0024 18.1 1.1 0.0071 16.5 0.0 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box MTS PF05175.9 CEH15554.1 - 0.0026 17.1 0.1 0.0066 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 CEH15554.1 - 0.01 14.9 0.0 0.062 12.4 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF3419 PF11899.3 CEH15554.1 - 0.031 12.9 0.0 0.085 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3419) Methyltransf_8 PF05148.10 CEH15554.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase R3H PF01424.17 CEH15556.1 - 2.8e-10 39.7 0.0 1.1e-09 37.8 0.0 2.1 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 CEH15556.1 - 1.7e-06 27.6 1.2 1.7e-06 27.6 0.8 2.6 2 0 0 2 2 2 1 G-patch domain Fcf1 PF04900.7 CEH15558.1 - 4.3e-38 129.4 0.4 7.3e-38 128.7 0.3 1.4 1 0 0 1 1 1 1 Fcf1 NDUF_B7 PF05676.8 CEH15559.1 - 2.3e-27 94.1 1.8 3e-27 93.7 1.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) IER PF05760.7 CEH15561.1 - 0.055 13.3 0.4 0.056 13.3 0.3 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Myb_DNA-binding PF00249.26 CEH15561.1 - 0.055 13.5 0.4 0.22 11.6 0.2 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain NAD_binding_1 PF00175.16 CEH15563.1 - 1.5e-07 31.9 0.0 1.9e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CEH15563.1 - 0.00056 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 CEH15563.1 - 0.0042 17.1 0.1 0.021 14.9 0.0 2.1 1 1 1 2 2 2 1 Oxidoreductase FAD-binding domain DnaJ PF00226.26 CEH15564.1 - 8.8e-20 70.2 0.4 8.8e-20 70.2 0.3 2.2 3 0 0 3 3 3 1 DnaJ domain BSP_II PF05432.6 CEH15564.1 - 1.1 8.4 26.2 0.019 14.2 12.6 1.9 2 1 0 2 2 2 0 Bone sialoprotein II (BSP-II) MIF4G_like PF09088.6 CEH15565.1 - 6.3e-57 192.0 0.0 2.7e-56 190.0 0.0 1.9 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 CEH15565.1 - 8.2e-36 123.5 0.0 1.4e-28 99.7 0.0 3.2 2 1 0 2 2 2 2 MIF4G like MCPVI PF02993.9 CEH15565.1 - 0.048 13.8 3.7 0.12 12.5 2.5 1.6 1 0 0 1 1 1 0 Minor capsid protein VI UbiA PF01040.13 CEH15566.1 - 1.4e-32 112.9 9.1 1.6e-32 112.7 6.3 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Dicty_REP PF05086.7 CEH15570.1 - 2.6 5.7 4.5 3.4 5.3 3.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NOG1 PF06858.9 CEH15571.1 - 1.1e-28 98.8 0.1 2.2e-28 97.9 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 CEH15571.1 - 9.1e-18 64.3 0.0 2.5e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEH15571.1 - 1.2e-08 34.4 0.0 2.5e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B NOGCT PF08155.6 CEH15571.1 - 8.9e-07 28.5 0.5 8.9e-07 28.5 0.3 2.4 1 1 1 2 2 2 1 NOGCT (NUC087) domain Miro PF08477.8 CEH15571.1 - 2.5e-05 24.7 0.0 7.8e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 CEH15571.1 - 0.011 14.9 0.0 0.1 11.7 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 CEH15571.1 - 0.015 14.4 0.0 0.032 13.3 0.0 1.6 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.22 CEH15571.1 - 0.052 12.9 0.1 0.41 10.0 0.0 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF1266 PF06889.6 CEH15571.1 - 0.39 10.4 4.5 1.2 8.9 3.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Dynamin_N PF00350.18 CEH15571.1 - 0.42 10.4 8.8 2.8 7.7 0.0 3.7 3 2 1 4 4 4 0 Dynamin family CDC45 PF02724.9 CEH15571.1 - 9.6 4.0 22.0 0.97 7.3 1.8 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF814 PF05670.8 CEH15572.1 - 4.8e-22 77.6 0.4 1.4e-21 76.1 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF814) DUF1777 PF08648.7 CEH15572.1 - 8.1 6.1 23.2 11 5.6 16.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Leuk-A4-hydro_C PF09127.6 CEH15573.1 - 0.014 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Myb_DNA-bind_6 PF13921.1 CEH15573.1 - 0.018 15.1 0.3 0.082 13.0 0.0 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CEH15573.1 - 0.068 13.2 0.1 0.38 10.8 0.1 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myc_N PF01056.13 CEH15573.1 - 0.16 11.1 8.5 0.22 10.6 5.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 CEH15573.1 - 0.2 10.1 11.9 0.21 10.0 8.3 1.0 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 CEH15573.1 - 4.1 4.9 6.6 4.9 4.7 4.6 1.1 1 0 0 1 1 1 0 Ycf1 PTPlike_phytase PF14566.1 CEH15574.1 - 8.9e-113 373.0 0.0 1.4e-36 125.7 0.0 3.3 3 0 0 3 3 3 3 Inositol hexakisphosphate Raffinose_syn PF05691.7 CEH15575.1 - 0.11 10.0 0.0 0.15 9.5 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 PrpF PF04303.8 CEH15576.1 - 5.1e-51 173.5 0.2 6.7e-35 120.5 0.0 3.1 3 0 0 3 3 3 3 PrpF protein ATP-synt_S1 PF05827.7 CEH15578.1 - 4.3e-06 26.2 3.8 0.0088 15.3 0.2 2.8 2 1 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) Glyco_hydro_63 PF03200.11 CEH15579.1 - 9.6e-206 685.2 0.0 1.6e-204 681.2 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 CEH15579.1 - 1.5e-09 37.0 0.3 2e-09 36.6 0.2 1.3 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.6 CEH15579.1 - 0.015 13.5 0.0 0.023 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase ATG_C PF09333.6 CEH15579.1 - 0.074 13.2 0.0 0.92 9.6 0.0 2.3 2 0 0 2 2 2 0 ATG C terminal domain DUF3369 PF11849.3 CEH15579.1 - 0.2 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) GST_N_3 PF13417.1 CEH15580.1 - 3.1e-16 59.3 0.0 5.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEH15580.1 - 1.3e-11 44.5 0.0 3.1e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEH15580.1 - 1.1e-09 38.1 0.0 2.2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CEH15580.1 - 3.3e-08 33.3 0.0 5.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEH15580.1 - 5.9e-07 29.8 0.1 9.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEH15580.1 - 1.1e-05 25.2 0.4 4e-05 23.4 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_16 PF00722.16 CEH15581.1 - 2.8e-15 56.0 0.1 7.4e-15 54.7 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 CEH15582.1 - 1.3e-42 145.7 4.0 1.3e-42 145.7 2.7 2.5 2 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEH15582.1 - 1e-08 35.2 0.1 8.4e-08 32.2 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CEH15582.1 - 2.3e-05 24.1 0.0 0.0006 19.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEH15582.1 - 0.0028 16.9 0.0 0.007 15.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 PAN_4 PF14295.1 CEH15583.1 - 0.00052 19.6 7.4 0.057 13.1 1.6 2.9 2 1 0 2 2 2 2 PAN domain PAN_1 PF00024.21 CEH15583.1 - 0.11 12.2 3.5 2.8 7.7 0.2 2.5 2 0 0 2 2 2 0 PAN domain WSC PF01822.14 CEH15584.1 - 1e-119 390.7 168.8 7.2e-18 64.3 9.9 9.5 10 0 0 10 10 10 8 WSC domain Abhydrolase_5 PF12695.2 CEH15584.1 - 0.0051 16.5 0.0 0.017 14.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CEH15584.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) WW PF00397.21 CEH15585.1 - 0.76 9.7 9.8 11 5.9 0.0 3.9 3 1 1 4 4 4 0 WW domain GTP_EFTU PF00009.22 CEH15588.1 - 2e-39 134.9 0.0 2.9e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CEH15588.1 - 2.3e-27 94.9 0.0 4.3e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CEH15588.1 - 1.3e-18 66.5 0.0 5.1e-18 64.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CEH15588.1 - 2.7e-09 36.9 0.2 2.6e-08 33.8 0.1 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Miro PF08477.8 CEH15588.1 - 1.6e-06 28.5 0.0 4.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein EFG_II PF14492.1 CEH15588.1 - 2.9e-06 27.0 0.1 2.8e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 CEH15588.1 - 1.5e-05 24.9 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CEH15588.1 - 0.0074 15.5 0.1 0.026 13.7 0.0 1.9 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CEH15588.1 - 0.032 13.6 0.0 0.11 11.8 0.0 1.8 1 1 0 1 1 1 0 Ras family GBP PF02263.14 CEH15588.1 - 0.089 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Cyclin_N PF00134.18 CEH15589.1 - 7.3e-09 35.2 0.2 0.0001 21.8 0.0 2.7 3 0 0 3 3 3 2 Cyclin, N-terminal domain GSK-3_bind PF05350.7 CEH15590.1 - 0.052 12.9 0.6 0.091 12.1 0.4 1.5 1 1 0 1 1 1 0 Glycogen synthase kinase-3 binding Defensin_2 PF01097.13 CEH15591.1 - 1.7e-05 24.4 17.4 0.0043 16.7 1.7 2.3 2 0 0 2 2 2 2 Arthropod defensin Toxin_3 PF00537.13 CEH15591.1 - 0.0031 17.3 5.7 0.0031 17.3 4.0 2.2 2 0 0 2 2 2 1 Scorpion toxin-like domain Gamma-thionin PF00304.15 CEH15591.1 - 0.074 13.0 19.8 0.63 10.0 3.3 2.3 2 0 0 2 2 2 0 Gamma-thionin family TCO89 PF10452.4 CEH15592.1 - 0.0017 17.3 1.2 0.0019 17.1 0.9 1.1 1 0 0 1 1 1 1 TORC1 subunit TCO89 DUF605 PF04652.11 CEH15592.1 - 0.13 11.6 3.2 0.16 11.3 2.2 1.1 1 0 0 1 1 1 0 Vta1 like DUF4226 PF10774.4 CEH15594.1 - 0.051 13.6 1.4 0.1 12.6 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) DUF2217 PF10265.4 CEH15594.1 - 0.23 10.1 4.9 0.3 9.7 3.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) WD40 PF00400.27 CEH15598.1 - 1.1e-33 113.9 5.5 1.6e-08 34.1 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 CEH15598.1 - 1.6e-22 79.3 5.0 2.5e-22 78.7 3.5 1.3 1 0 0 1 1 1 1 Sof1-like domain PQQ_3 PF13570.1 CEH15598.1 - 0.021 15.0 0.2 25 5.3 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain Abhydrolase_6 PF12697.2 CEH15599.1 - 6.7e-27 94.8 0.0 8e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH15599.1 - 8.3e-15 54.8 0.4 5.6e-14 52.1 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH15599.1 - 3.7e-09 36.4 0.3 7.4e-09 35.5 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CEH15599.1 - 3.7e-07 29.9 1.5 6.7e-07 29.0 0.1 2.3 3 1 0 3 3 3 1 Putative lysophospholipase Ndr PF03096.9 CEH15599.1 - 0.00066 18.2 0.1 0.0078 14.7 0.1 2.1 1 1 0 1 1 1 1 Ndr family DUF4134 PF13572.1 CEH15599.1 - 0.029 14.4 0.0 0.08 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) Thioesterase PF00975.15 CEH15599.1 - 0.03 14.5 0.0 0.07 13.3 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain AXE1 PF05448.7 CEH15599.1 - 0.059 11.8 0.0 0.081 11.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 CEH15599.1 - 0.13 11.1 1.0 0.23 10.3 0.1 1.8 2 1 0 2 2 2 0 Chlorophyllase enzyme WD40 PF00400.27 CEH15600.1 - 1e-27 94.9 15.3 2.8e-13 49.1 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat CLTH PF10607.4 CEH15600.1 - 0.0033 17.1 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain eIF2A PF08662.6 CEH15600.1 - 0.079 12.6 0.0 6.8 6.3 0.0 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A TFIID_20kDa PF03847.8 CEH15601.1 - 7.3e-32 109.4 0.4 9.9e-32 109.0 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 CEH15601.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aldo_ket_red PF00248.16 CEH15604.1 - 1.1e-21 76.9 0.0 3e-11 42.6 0.0 2.9 2 1 0 2 2 2 2 Aldo/keto reductase family ADH_zinc_N PF00107.21 CEH15605.1 - 3.1e-26 91.4 0.0 4.5e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH15605.1 - 1e-09 39.3 0.0 3.5e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH15605.1 - 1.5e-08 34.3 0.0 6.2e-08 32.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain GAF_2 PF13185.1 CEH15606.1 - 0.018 15.5 0.1 0.24 11.8 0.0 2.3 2 1 0 2 2 2 0 GAF domain Peptidase_S8 PF00082.17 CEH15607.1 - 3.3e-57 193.8 2.6 4.6e-57 193.3 1.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CEH15607.1 - 4.1e-27 93.7 0.2 8.6e-27 92.7 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Syja_N PF02383.13 CEH15608.1 - 7.1e-84 281.2 0.0 1.1e-83 280.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 CEH15608.1 - 4.8e-24 83.9 0.0 9.2e-24 83.0 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase ATP_synt_H PF05493.8 CEH15609.1 - 3.5e-23 81.4 2.4 4.6e-23 81.0 1.7 1.2 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.1 CEH15609.1 - 0.0068 16.2 0.1 0.0075 16.1 0.0 1.2 1 0 0 1 1 1 1 Haemopoietic lineage transmembrane helix APH PF01636.18 CEH15610.1 - 2.1e-10 40.7 1.9 5.7e-10 39.3 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEH15610.1 - 4.4e-10 39.4 0.0 1.5e-08 34.4 0.0 2.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase Asp PF00026.18 CEH15611.1 - 5.5e-64 216.3 1.5 5.5e-64 216.3 1.0 1.5 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEH15611.1 - 1e-05 25.5 0.1 0.00013 21.9 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CEH15611.1 - 0.0023 18.4 0.9 0.37 11.3 0.1 3.0 2 1 0 2 2 2 1 Aspartyl protease Lysis_col PF02402.11 CEH15611.1 - 0.06 12.9 1.2 14 5.4 0.1 2.8 2 0 0 2 2 2 0 Lysis protein ArfGap PF01412.13 CEH15611.1 - 0.094 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf FixH PF05751.6 CEH15611.1 - 0.13 12.0 0.0 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 FixH Peptidase_M24 PF00557.19 CEH15612.1 - 1.3e-40 139.2 0.1 2e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M19 PF01244.16 CEH15614.1 - 0.063 12.1 0.0 0.064 12.1 0.0 1.0 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) SSI PF00720.12 CEH15614.1 - 0.21 11.5 1.2 0.24 11.3 0.6 1.3 1 1 0 1 1 1 0 Subtilisin inhibitor-like Chitin_synth_1 PF01644.12 CEH15616.1 - 4.2e-68 228.2 0.8 6.5e-68 227.6 0.5 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 CEH15616.1 - 1.2e-27 96.5 0.2 9.2e-21 73.8 0.0 3.1 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 CEH15616.1 - 3.5e-22 77.8 0.1 7.7e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 CEH15616.1 - 3.8e-11 43.0 0.4 3.8e-11 43.0 0.3 2.4 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEH15616.1 - 1e-10 41.8 0.0 2.6e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Aminotran_5 PF00266.14 CEH15618.1 - 3.7e-30 104.8 0.0 5.2e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 CEH15618.1 - 0.017 14.9 0.0 0.045 13.6 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain UPF0180 PF03698.8 CEH15618.1 - 0.067 13.0 0.1 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) DUF1748 PF08520.5 CEH15620.1 - 5.1e-21 74.0 0.0 6.4e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Asp PF00026.18 CEH15622.1 - 3.5e-60 203.9 0.2 4.2e-60 203.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEH15622.1 - 9.6e-07 28.8 0.0 8e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Pyocin_S PF06958.7 CEH15623.1 - 0.1 12.9 3.2 0.14 12.4 2.2 1.2 1 0 0 1 1 1 0 S-type Pyocin UQ_con PF00179.21 CEH15624.1 - 6.3e-38 129.3 0.0 8.1e-38 129.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CEH15624.1 - 0.033 14.0 0.1 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 CEH15624.1 - 0.078 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.8 CEH15624.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 1 0 1 1 1 0 UEV domain 6PF2K PF01591.13 CEH15626.1 - 9.1e-71 237.4 0.0 1.3e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CEH15626.1 - 3.5e-21 75.9 0.0 8.6e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CEH15626.1 - 3.6e-09 36.6 0.0 1.1e-08 35.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEH15626.1 - 0.00021 22.0 0.0 0.0008 20.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain NO_synthase PF02898.10 CEH15626.1 - 0.0056 15.3 0.0 0.0085 14.8 0.0 1.1 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain Zeta_toxin PF06414.7 CEH15626.1 - 0.03 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin GBP PF02263.14 CEH15626.1 - 0.064 12.3 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain KTI12 PF08433.5 CEH15626.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SKG6 PF08693.5 CEH15628.1 - 0.12 11.6 7.0 0.22 10.8 4.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 CEH15628.1 - 0.14 10.3 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Transket_pyr PF02779.19 CEH15630.1 - 3.6e-45 153.6 0.0 5.4e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CEH15630.1 - 7e-38 129.3 0.0 1.3e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain COX15-CtaA PF02628.10 CEH15631.1 - 2.8e-76 256.3 11.9 3.4e-76 256.0 8.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Pribosyltran_N PF13793.1 CEH15632.1 - 3.3e-45 152.5 0.2 7.9e-44 148.1 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CEH15632.1 - 2.1e-39 135.1 3.4 5e-33 114.3 0.2 2.8 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CEH15632.1 - 9.4e-12 44.7 1.1 5.4e-11 42.3 0.4 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CEH15632.1 - 0.0043 16.2 0.1 0.0082 15.3 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DC_STAMP PF07782.8 CEH15632.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 DC-STAMP-like protein TACI-CRD2 PF09305.5 CEH15633.1 - 0.069 12.9 0.4 2.5 7.9 0.0 2.1 1 1 1 2 2 2 0 TACI, cysteine-rich domain Iso_dh PF00180.15 CEH15634.1 - 1.6e-73 247.6 0.0 1.8e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3364 PF11844.3 CEH15634.1 - 0.16 11.9 1.4 3.7 7.6 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3364) RRM_6 PF14259.1 CEH15635.1 - 2.7e-10 40.0 0.0 4.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEH15635.1 - 3.2e-09 36.2 0.0 4.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LsmAD PF06741.8 CEH15637.1 - 8e-22 77.1 2.3 1.3e-21 76.4 1.6 1.3 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 CEH15637.1 - 6.6e-10 38.7 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain AMP-binding PF00501.23 CEH15638.1 - 2.6e-49 167.7 0.0 3e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Ig_Tie2_1 PF10430.4 CEH15638.1 - 0.035 14.4 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 AMP-binding PF00501.23 CEH15639.1 - 1.1e-09 37.2 0.3 1.6e-09 36.6 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEH15639.1 - 1.5e-08 35.4 0.3 2.5e-08 34.7 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-B_box PF00643.19 CEH15640.1 - 0.00048 19.9 3.8 0.00048 19.9 2.6 2.0 2 0 0 2 2 2 1 B-box zinc finger DUF4573 PF15140.1 CEH15640.1 - 0.025 14.1 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) zf-HIT PF04438.11 CEH15640.1 - 2.1 8.0 7.0 0.76 9.4 3.1 1.5 2 0 0 2 2 2 0 HIT zinc finger Fungal_trans PF04082.13 CEH15641.1 - 1.8e-19 69.6 0.1 3e-19 68.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH15641.1 - 9.2e-05 22.2 15.0 0.00018 21.3 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAGK_cat PF00781.19 CEH15642.1 - 3.6e-13 49.0 0.0 7.5e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF1308 PF07000.6 CEH15644.1 - 2.7e-19 69.0 0.0 4.6e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) LCCL PF03815.14 CEH15644.1 - 7e-14 51.5 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain DUF3413 PF11893.3 CEH15644.1 - 0.4 9.5 4.6 0.13 11.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) DUF229 PF02995.12 CEH15644.1 - 0.5 8.7 0.0 0.76 8.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Gpi1 PF05024.10 CEH15645.1 - 2.1e-46 158.0 4.6 3e-46 157.4 3.2 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Mad3_BUB1_I PF08311.7 CEH15646.1 - 7.1e-30 103.3 0.1 1.3e-29 102.4 0.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 CEH15646.1 - 3.5e-14 52.5 0.0 5.8e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15646.1 - 0.001 18.1 0.0 0.0024 16.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase 6PGD PF00393.14 CEH15647.1 - 2.8e-135 450.1 0.0 3.5e-135 449.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CEH15647.1 - 1.2e-53 181.3 0.0 1.7e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CEH15647.1 - 0.027 14.5 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 CEH15647.1 - 0.038 14.4 0.1 0.075 13.4 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent G-gamma PF00631.17 CEH15648.1 - 1.7e-23 82.1 0.0 1.9e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 GGL domain FPN1 PF06963.7 CEH15649.1 - 1.4e-116 389.4 10.9 1.7e-116 389.1 7.5 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) TMEM154 PF15102.1 CEH15650.1 - 0.023 14.4 0.2 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Herpes_gE PF02480.11 CEH15650.1 - 0.041 12.1 0.2 0.072 11.3 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ctr PF04145.10 CEH15650.1 - 0.27 11.3 0.0 0.85 9.6 0.0 1.9 1 0 0 1 1 1 0 Ctr copper transporter family Glyoxal_oxid_N PF07250.6 CEH15651.1 - 1.2e-36 125.9 0.0 7.6e-35 120.1 0.0 2.6 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CEH15651.1 - 3.8e-25 87.8 0.4 8.2e-25 86.7 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 CEH15651.1 - 0.19 11.5 4.9 16 5.3 0.0 4.2 4 0 0 4 4 4 0 Galactose oxidase, central domain WD40 PF00400.27 CEH15652.1 - 4.7e-20 70.6 9.3 3.3e-06 26.7 0.5 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 CEH15652.1 - 0.23 11.1 0.0 0.45 10.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Methyltransf_23 PF13489.1 CEH15656.1 - 5.8e-12 45.6 0.0 8.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH15656.1 - 1.3e-05 25.6 0.0 3.1e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH15656.1 - 2e-05 24.2 0.0 3.9e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH15656.1 - 0.00018 21.4 0.0 0.00052 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH15656.1 - 0.00039 20.9 0.0 0.00083 19.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEH15656.1 - 0.00049 19.2 0.0 0.0013 17.8 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CEH15656.1 - 0.00064 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH15656.1 - 0.0024 18.3 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 CEH15656.1 - 0.0024 17.1 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain NNMT_PNMT_TEMT PF01234.12 CEH15656.1 - 0.098 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family NodS PF05401.6 CEH15656.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) SART-1 PF03343.8 CEH15659.1 - 1.4e-105 353.9 39.1 4e-105 352.4 27.1 1.7 1 1 0 1 1 1 1 SART-1 family G-patch_2 PF12656.2 CEH15660.1 - 1.6e-26 91.9 0.4 5.9e-26 90.1 0.3 2.1 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 CEH15660.1 - 1.7e-09 37.3 2.3 3.5e-09 36.3 1.6 1.6 1 0 0 1 1 1 1 G-patch domain ABC_tran PF00005.22 CEH15661.1 - 2.9e-35 121.5 0.0 6.6e-35 120.3 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 CEH15661.1 - 6.7e-31 107.7 5.1 9.1e-31 107.2 3.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CEH15661.1 - 1.2e-05 25.4 0.2 0.0087 16.0 0.0 2.7 2 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CEH15661.1 - 0.00036 20.5 0.0 0.002 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CEH15661.1 - 0.0025 17.7 0.0 0.12 12.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CEH15661.1 - 0.0075 15.9 0.0 0.067 12.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CEH15661.1 - 0.0094 16.0 0.0 0.031 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CEH15661.1 - 0.0098 15.4 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CEH15661.1 - 0.013 16.3 0.0 0.03 15.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 CEH15661.1 - 0.018 14.2 0.0 1.3 8.2 0.0 2.5 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 CEH15661.1 - 0.019 15.1 0.0 0.18 12.0 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CEH15661.1 - 0.026 14.4 0.1 3.4 7.5 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CEH15661.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 CEH15661.1 - 0.063 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CEH15661.1 - 0.064 12.6 0.1 0.35 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CEH15661.1 - 0.07 13.4 0.6 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 CEH15661.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 CEH15661.1 - 0.15 12.0 0.1 0.88 9.5 0.0 2.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF258 PF03193.11 CEH15661.1 - 0.16 11.1 0.0 0.41 9.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Acyltransferase PF01553.16 CEH15663.1 - 5.2e-19 67.9 0.0 1.1e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase NAD_binding_10 PF13460.1 CEH15664.1 - 0.0048 16.9 0.0 0.04 13.9 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding MFS_1 PF07690.11 CEH15665.1 - 4.1e-29 101.3 30.3 6.4e-29 100.7 21.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PIRT PF15099.1 CEH15665.1 - 0.059 12.5 1.1 0.18 11.0 0.7 1.8 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family CD34_antigen PF06365.7 CEH15665.1 - 0.23 11.1 0.0 0.43 10.2 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family 4HBT_2 PF13279.1 CEH15666.1 - 2.7e-10 40.7 0.0 9.5e-10 38.9 0.0 1.9 1 1 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 CEH15666.1 - 3.9e-05 23.6 0.0 0.00038 20.5 0.0 2.4 1 1 1 2 2 2 1 Thioesterase superfamily COesterase PF00135.23 CEH15668.1 - 1.5e-87 294.5 0.1 2.2e-87 294.0 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CEH15668.1 - 2e-06 27.5 0.1 4.5e-06 26.3 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEH15668.1 - 0.033 13.3 0.1 0.057 12.6 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lung_7-TM_R PF06814.8 CEH15669.1 - 2.9e-34 118.3 17.6 1.1e-33 116.5 12.2 1.7 1 1 0 1 1 1 1 Lung seven transmembrane receptor LBR_tudor PF09465.5 CEH15670.1 - 0.09 12.4 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain ICL PF00463.16 CEH15671.1 - 5.8e-163 542.8 0.4 6.5e-163 542.6 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CEH15671.1 - 5.1e-05 22.6 0.1 8.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 CEH15671.1 - 0.032 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Carn_acyltransf PF00755.15 CEH15673.1 - 4.2e-166 553.5 0.0 4.8e-166 553.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pkinase PF00069.20 CEH15674.1 - 1.8e-65 220.6 0.0 2.3e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15674.1 - 1.8e-28 99.3 0.0 2.9e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CEH15674.1 - 1.2e-11 44.9 0.0 6.3e-11 42.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CEH15674.1 - 9.6e-08 31.3 0.0 4e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 CEH15674.1 - 8.5e-06 25.5 0.0 7.6e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 C2 domain APH PF01636.18 CEH15674.1 - 0.043 13.5 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CEH15674.1 - 0.17 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.19 CEH15675.1 - 1.4e-102 343.6 16.1 1.7e-102 343.3 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH15675.1 - 7.3e-15 54.5 38.3 5e-10 38.6 9.4 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_3 PF01596.12 CEH15677.1 - 4.4e-30 104.2 0.0 5.5e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 CEH15677.1 - 1e-05 26.2 0.0 1.7e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_4 PF07993.7 CEH15678.1 - 1.6e-27 96.0 0.0 8.5e-27 93.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 CEH15678.1 - 7e-08 32.1 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CEH15678.1 - 5.6e-06 26.1 1.3 1.7e-05 24.5 0.9 1.8 1 1 0 1 1 1 1 KR domain PP-binding PF00550.20 CEH15678.1 - 9.1e-06 25.8 0.1 4.7e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 CEH15678.1 - 0.00019 21.4 0.8 0.0021 18.0 0.6 2.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CEH15678.1 - 0.0094 14.8 0.4 3.6 6.3 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain AMP-binding_C PF13193.1 CEH15678.1 - 0.015 16.2 0.0 1.5 9.7 0.0 3.1 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 CEH15678.1 - 0.018 13.7 0.0 0.034 12.8 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CEH15678.1 - 0.068 13.0 6.0 0.049 13.5 2.3 2.3 2 1 0 2 2 2 0 short chain dehydrogenase Aldo_ket_red PF00248.16 CEH15679.1 - 4.8e-68 229.0 0.0 5.4e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AP_endonuc_2 PF01261.19 CEH15679.1 - 0.11 11.8 0.0 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DHQ_synthase PF01761.15 CEH15680.1 - 2.2e-48 164.4 0.0 2.9e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 CEH15680.1 - 1.7e-12 47.1 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Peptidase_M28 PF04389.12 CEH15681.1 - 1.9e-24 86.3 0.0 3.1e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CEH15681.1 - 3.2e-08 33.2 0.1 8.9e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 TPR_2 PF07719.12 CEH15682.1 - 7e-27 91.1 8.4 6.3e-05 22.5 0.0 9.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 CEH15682.1 - 1.2e-22 79.3 11.7 3.9e-08 32.8 0.0 6.6 7 0 0 7 7 7 3 TPR repeat TPR_1 PF00515.23 CEH15682.1 - 3.3e-21 73.9 0.0 0.00033 20.1 0.0 7.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 CEH15682.1 - 8.3e-15 53.3 0.0 0.047 13.4 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 CEH15682.1 - 1.1e-14 54.0 15.0 2.5e-08 33.7 0.5 7.4 6 2 1 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CEH15682.1 - 6.9e-14 51.7 7.5 9.2e-05 22.5 0.1 5.3 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CEH15682.1 - 1.9e-10 41.1 20.4 3.2e-05 24.4 0.1 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEH15682.1 - 2.2e-09 37.5 1.9 0.13 12.5 0.0 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 CEH15682.1 - 9e-07 28.6 7.1 0.054 13.7 0.0 6.8 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEH15682.1 - 1.2e-06 28.5 2.8 1.2 9.7 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEH15682.1 - 2.5e-06 26.8 0.6 3 7.8 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH15682.1 - 1.1e-05 25.6 21.4 0.017 15.7 0.1 8.3 6 2 3 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 CEH15682.1 - 0.00028 20.6 7.5 1.7 8.5 0.0 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 CEH15682.1 - 0.0059 16.4 10.9 0.73 9.8 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 CEH15682.1 - 0.018 14.7 1.5 23 4.9 0.5 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 CEH15682.1 - 0.04 14.3 9.3 3.6 8.2 0.3 6.2 5 1 0 5 5 5 0 Tetratricopeptide repeat Peptidase_M18 PF02127.10 CEH15683.1 - 4.1e-154 513.2 0.0 4.8e-154 513.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CEH15683.1 - 0.001 17.9 0.0 0.38 9.4 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase WD40 PF00400.27 CEH15684.1 - 1.9e-24 84.5 9.8 5.3e-10 38.7 0.3 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CEH15684.1 - 2.5e-17 62.5 0.0 8e-17 60.9 0.0 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 CEH15684.1 - 1.7e-06 27.9 0.2 1.6e-05 24.7 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 CEH15684.1 - 0.039 11.7 0.2 0.69 7.6 0.1 2.1 1 1 1 2 2 2 0 IKI3 family PMP22_Claudin PF00822.15 CEH15685.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family CDK2AP PF09806.4 CEH15685.1 - 2.3 8.4 12.6 1.9 8.6 1.3 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ferritin_2 PF13668.1 CEH15687.1 - 1.8e-43 147.7 5.3 3.9e-43 146.6 3.7 1.6 1 0 0 1 1 1 1 Ferritin-like domain Fungal_trans_2 PF11951.3 CEH15688.1 - 4.1e-07 28.9 3.7 1.2e-06 27.4 2.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain PEX11 PF05648.9 CEH15689.1 - 1.4e-59 201.1 2.3 1.5e-59 200.9 1.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3635 PF12330.3 CEH15690.1 - 3.2e-11 43.1 0.7 8.2e-06 25.8 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3635) APH PF01636.18 CEH15690.1 - 0.091 12.4 2.4 0.8 9.3 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family RCC1 PF00415.13 CEH15691.1 - 4.8e-19 68.3 11.9 0.00087 19.4 0.1 8.2 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CEH15691.1 - 1.1e-10 40.7 25.0 0.0066 16.0 0.6 7.5 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.17 CEH15692.1 - 1.1e-06 28.2 0.0 2.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH15692.1 - 1.3e-06 28.2 0.0 2.2e-05 24.3 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH15692.1 - 4.1e-05 23.3 0.0 8.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HALZ PF02183.13 CEH15692.1 - 0.17 11.6 2.0 0.31 10.7 1.4 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper AdoMet_MTase PF07757.8 CEH15693.1 - 1.3e-33 115.4 0.3 1.2e-15 57.5 0.1 2.4 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 CEH15693.1 - 0.0026 17.4 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain M20_dimer PF07687.9 CEH15694.1 - 8.4e-11 41.6 0.2 2.8e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 CEH15694.1 - 1.8e-09 37.3 0.1 2.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TLD PF07534.11 CEH15695.1 - 3.5e-25 88.5 0.0 1.1e-23 83.7 0.0 2.5 2 0 0 2 2 2 1 TLD DUF4632 PF15451.1 CEH15695.1 - 0.012 15.4 0.3 0.049 13.5 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Ribosomal_L1 PF00687.16 CEH15696.1 - 2.5e-17 62.9 0.0 2e-15 56.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein L1p/L10e family SNF2_N PF00176.18 CEH15697.1 - 3.3e-55 186.9 0.0 4.6e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEH15697.1 - 1.7e-15 56.6 0.0 4.1e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CEH15697.1 - 1.1e-11 44.1 0.1 2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CEH15697.1 - 0.0065 16.3 0.0 0.059 13.2 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Chromo PF00385.19 CEH15697.1 - 0.0075 15.9 0.4 0.11 12.1 0.1 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Sas10_Utp3 PF04000.10 CEH15698.1 - 2.8e-11 43.4 1.5 2.8e-11 43.4 1.0 3.2 2 2 0 2 2 2 1 Sas10/Utp3/C1D family SOBP PF15279.1 CEH15698.1 - 3.8 7.7 14.2 13 6.0 0.0 2.0 2 0 0 2 2 2 0 Sine oculis-binding protein DUF1192 PF06698.6 CEH15700.1 - 0.1 12.3 0.6 0.3 10.9 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) PP-binding PF00550.20 CEH15701.1 - 9.1e-15 54.6 0.4 1.3e-14 54.2 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CEH15701.1 - 1.6e-06 28.0 0.1 2.4e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 CEH15701.1 - 0.076 12.9 0.1 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Ribosomal subunit 39S ABC1 PF03109.11 CEH15702.1 - 4.1e-23 81.6 0.0 2.5e-15 56.4 0.0 2.3 2 0 0 2 2 2 2 ABC1 family RhoGEF PF00621.15 CEH15703.1 - 1.1e-36 126.4 0.0 1.7e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.1 CEH15703.1 - 3.1e-08 33.2 0.2 0.00022 20.9 0.0 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CEH15703.1 - 1.5e-06 27.7 0.5 0.016 14.7 0.0 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEH15703.1 - 0.0021 17.8 0.7 2.1 8.6 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 CEH15703.1 - 0.091 13.0 1.3 35 5.2 0.0 3.7 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 CEH15703.1 - 0.13 12.3 2.6 0.32 11.1 0.1 3.1 4 0 0 4 4 4 0 Leucine Rich repeat Pkr1 PF08636.5 CEH15704.1 - 1.5e-15 56.9 0.3 1.9e-15 56.6 0.2 1.1 1 0 0 1 1 1 1 ER protein Pkr1 ABC-3 PF00950.12 CEH15704.1 - 0.0021 17.3 0.2 0.0023 17.2 0.1 1.1 1 0 0 1 1 1 1 ABC 3 transport family DUF3796 PF12676.2 CEH15704.1 - 0.051 13.7 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) SKIP_SNW PF02731.10 CEH15705.1 - 1.5e-63 213.0 0.3 1.5e-63 213.0 0.2 2.4 2 0 0 2 2 2 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.7 CEH15705.1 - 0.015 14.9 10.1 0.055 13.1 7.0 1.9 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ApbA_C PF08546.6 CEH15706.1 - 3.2e-34 117.6 0.2 5.5e-34 116.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CEH15706.1 - 9.1e-18 64.1 0.0 1.3e-13 50.6 0.0 2.8 3 0 0 3 3 3 2 Ketopantoate reductase PanE/ApbA AMP-binding PF00501.23 CEH15707.1 - 7.4e-48 162.9 0.0 1.2e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 CEH15707.1 - 1.8e-12 46.1 2.6 0.0005 19.4 0.0 6.9 7 1 0 7 7 7 3 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 CEH15707.1 - 2.5e-12 46.8 0.6 5e-12 45.9 0.4 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 CEH15707.1 - 2.1e-10 41.3 3.2 9.6e-06 26.4 0.0 3.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.1 CEH15707.1 - 0.58 9.7 12.3 8.2 6.0 0.0 5.4 4 2 2 6 6 6 0 Hexapeptide repeat of succinyl-transferase GH3 PF03321.8 CEH15707.1 - 0.73 8.2 0.0 15 3.9 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Myb_Cef PF11831.3 CEH15710.1 - 1e-58 198.2 1.0 1e-58 198.2 0.7 4.2 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 CEH15710.1 - 4.7e-22 77.7 5.9 3.3e-11 43.0 0.4 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH15710.1 - 6.4e-20 71.0 9.1 1.5e-13 50.5 3.0 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 CEH15710.1 - 0.00092 18.6 0.7 0.26 10.8 0.0 3.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain Cpn60_TCP1 PF00118.19 CEH15711.1 - 2.9e-136 454.9 0.1 3.6e-136 454.6 0.1 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 CEH15711.1 - 0.19 11.6 5.9 0.9 9.4 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain RNA_pol_L_2 PF13656.1 CEH15712.1 - 8.5e-29 98.8 0.0 2.7e-28 97.1 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CEH15712.1 - 1.1e-11 43.6 0.0 1.6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2305 PF10230.4 CEH15714.1 - 1e-49 169.3 0.0 2.8e-49 167.9 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 CEH15714.1 - 1.7e-12 47.7 2.9 1.7e-12 47.6 1.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH15714.1 - 0.00024 20.8 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CEH15714.1 - 0.042 14.0 0.1 0.14 12.3 0.1 2.0 1 1 0 1 1 1 0 Thioesterase domain Ras PF00071.17 CEH15715.1 - 3.1e-54 182.7 0.0 3.5e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH15715.1 - 7.5e-18 65.1 0.0 9.6e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH15715.1 - 1.4e-05 24.4 0.0 1.9e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Tetraspannin PF00335.15 CEH15716.1 - 0.94 8.7 9.9 0.12 11.5 3.7 1.7 1 1 0 1 1 1 0 Tetraspanin family PepSY_TM_2 PF13703.1 CEH15716.1 - 9.2 6.5 7.4 6 7.1 0.6 2.7 2 1 0 2 2 2 0 PepSY-associated TM helix GTP_EFTU PF00009.22 CEH15719.1 - 2e-62 209.9 0.2 2.7e-62 209.5 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CEH15719.1 - 4.7e-38 129.4 0.0 1.1e-37 128.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CEH15719.1 - 4.2e-17 61.7 0.0 1e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CEH15719.1 - 1.5e-14 53.6 0.0 3.7e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CEH15719.1 - 6.5e-13 48.6 0.1 5.7e-12 45.5 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEH15719.1 - 1.4e-06 28.2 0.1 2.7e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase CN_hydrolase PF00795.17 CEH15720.1 - 1.9e-10 40.4 0.0 1.8e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Kelch_4 PF13418.1 CEH15721.1 - 7.5e-32 108.8 15.3 5.5e-11 42.0 0.4 5.4 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 CEH15721.1 - 3.8e-31 106.5 9.8 3.7e-11 42.8 0.1 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CEH15721.1 - 3.1e-25 87.6 7.7 3e-09 36.6 0.1 4.7 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CEH15721.1 - 1e-24 85.8 9.7 1.8e-11 43.3 0.5 4.7 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 CEH15721.1 - 4.1e-22 77.3 9.5 9.5e-10 38.2 0.3 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.10 CEH15721.1 - 3.1e-16 58.4 7.5 1.1e-05 25.0 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Vac_Fusion PF02346.11 CEH15721.1 - 1.3 8.4 10.5 12 5.4 1.9 4.4 3 1 1 4 4 4 0 Chordopoxvirus fusion protein FlaC_arch PF05377.6 CEH15721.1 - 3.6 7.5 16.5 0.12 12.3 0.7 5.4 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) WD40 PF00400.27 CEH15723.1 - 1.2e-22 78.8 3.7 1.8e-06 27.6 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 CEH15723.1 - 0.0094 14.1 0.1 0.028 12.5 0.0 1.8 1 1 0 1 1 1 1 Nucleoporin Nup120/160 IKI3 PF04762.7 CEH15723.1 - 0.01 13.6 0.2 0.67 7.6 0.1 2.4 2 0 0 2 2 2 0 IKI3 family PRP38 PF03371.10 CEH15724.1 - 9.9e-61 204.3 0.1 1.2e-60 204.0 0.1 1.0 1 0 0 1 1 1 1 PRP38 family DASH_Ask1 PF08655.5 CEH15725.1 - 4.9e-25 87.1 0.0 7.3e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 PgaD PF13994.1 CEH15726.1 - 0.19 11.2 0.7 0.34 10.3 0.5 1.3 1 0 0 1 1 1 0 PgaD-like protein RNA_pol_A_bac PF01000.21 CEH15727.1 - 6.4e-25 87.5 0.0 1.1e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CEH15727.1 - 4.4e-16 57.7 0.0 7e-16 57.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RRM_1 PF00076.17 CEH15728.1 - 7.8e-13 47.8 0.1 8e-10 38.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH15728.1 - 7.6e-08 32.0 0.6 3.5e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH15728.1 - 2.7e-07 30.4 0.1 1.2e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Beta_elim_lyase PF01212.16 CEH15728.1 - 0.0024 17.0 0.4 0.0041 16.3 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase CPL PF08144.6 CEH15728.1 - 0.04 13.7 1.8 6 6.7 0.0 2.3 2 0 0 2 2 2 0 CPL (NUC119) domain RBM39linker PF15519.1 CEH15728.1 - 1.8 8.9 8.6 7.4 6.9 0.1 3.1 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein TRAP-gamma PF07074.7 CEH15728.1 - 3.5 7.1 5.9 18 4.8 0.1 2.8 3 1 0 3 3 3 0 Translocon-associated protein, gamma subunit (TRAP-gamma) VCX_VCY PF15231.1 CEH15728.1 - 4.1 7.7 12.8 0.85 10.0 1.0 2.4 1 1 1 2 2 2 0 Variable charge X/Y family VHS PF00790.14 CEH15729.1 - 1.4e-22 79.8 0.0 4.5e-22 78.2 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 CEH15729.1 - 2e-07 30.9 1.6 6e-07 29.3 1.1 1.8 1 0 0 1 1 1 1 GAT domain Orthopox_A5L PF06193.6 CEH15729.1 - 0.43 10.5 10.0 0.12 12.2 4.0 2.0 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like PROL5-SMR PF15621.1 CEH15730.1 - 1.7 9.1 4.9 5.1 7.5 2.9 2.2 1 1 1 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF4210 PF13915.1 CEH15731.1 - 8.9e-21 73.9 0.0 1.7e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) JmjC PF02373.17 CEH15731.1 - 0.0016 18.6 0.1 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CEH15731.1 - 0.0024 17.4 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 CEH15731.1 - 0.0037 16.7 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 Cupin domain GPI PF06560.6 CEH15731.1 - 0.031 13.3 0.1 0.074 12.0 0.0 1.6 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Cupin_4 PF08007.7 CEH15731.1 - 0.083 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Pkinase PF00069.20 CEH15733.1 - 3.9e-39 134.3 0.0 5e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15733.1 - 7.9e-16 57.8 0.0 1e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH15733.1 - 1.3e-05 25.1 0.0 0.0032 17.2 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CEH15733.1 - 0.025 13.3 0.1 0.037 12.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CEH15733.1 - 0.088 11.8 0.0 0.31 10.0 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.19 CEH15735.1 - 1.3e-99 333.8 20.7 1.6e-99 333.4 14.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH15735.1 - 5.5e-30 104.2 21.8 2.2e-29 102.3 15.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CEH15735.1 - 0.0084 15.8 0.2 0.028 14.2 0.1 1.9 1 0 0 1 1 1 1 MFS_1 like family PAXNEB PF05625.6 CEH15736.1 - 3.1e-10 39.4 0.0 4.8e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein DUF1178 PF06676.6 CEH15737.1 - 0.028 14.6 0.3 0.037 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) SNF2_N PF00176.18 CEH15738.1 - 5.1e-64 215.9 0.0 8e-64 215.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEH15738.1 - 3.3e-11 42.8 0.0 8.3e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 CEH15738.1 - 7.2e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-RING_5 PF14634.1 CEH15738.1 - 0.00069 19.2 7.0 0.0018 17.9 4.4 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CEH15738.1 - 0.0081 15.8 7.8 0.06 13.0 4.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 CEH15738.1 - 0.0088 15.8 0.0 0.45 10.3 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_4 PF13871.1 CEH15738.1 - 0.024 14.0 0.2 3.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Helicase_C-like zf-RING_2 PF13639.1 CEH15738.1 - 0.19 11.5 5.4 0.43 10.4 3.8 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CEH15738.1 - 0.28 11.2 7.3 0.055 13.5 1.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) QRPTase_C PF01729.14 CEH15739.1 - 2.5e-49 167.0 0.3 3.1e-49 166.7 0.2 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 CEH15739.1 - 2.5e-22 78.4 0.0 7.5e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain IPT PF01745.11 CEH15739.1 - 0.11 11.7 0.0 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 Isopentenyl transferase Tubulin PF00091.20 CEH15740.1 - 7.9e-64 215.4 0.0 1.1e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CEH15740.1 - 3.6e-44 149.8 0.0 5.3e-44 149.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CEH15740.1 - 5e-06 26.5 0.0 9.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain RasGAP PF00616.14 CEH15740.1 - 0.0034 17.0 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Tubulin_3 PF14881.1 CEH15740.1 - 0.033 13.6 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.1 CEH15740.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Pkinase PF00069.20 CEH15741.1 - 2.9e-50 170.8 0.0 5.8e-50 169.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15741.1 - 1.4e-21 76.7 0.0 1.9e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH15741.1 - 2.2e-05 23.5 0.0 4.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like zf-C2H2 PF00096.21 CEH15742.1 - 4.3e-08 33.0 16.5 3.6e-05 23.8 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEH15742.1 - 3.1e-06 27.1 3.7 3.1e-06 27.1 2.6 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 CEH15742.1 - 0.00058 19.9 4.2 0.0068 16.5 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CEH15742.1 - 0.00097 19.2 0.2 0.0028 17.7 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CEH15742.1 - 0.0039 17.4 1.1 0.0039 17.4 0.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEH15742.1 - 0.082 12.8 0.2 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger NARP1 PF12569.3 CEH15743.1 - 6.8e-155 516.7 4.8 6.8e-155 516.7 3.3 1.7 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 CEH15743.1 - 2.3e-13 48.9 18.5 0.00035 20.2 0.0 11.2 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH15743.1 - 1.4e-11 43.9 32.2 0.0016 18.9 0.0 11.8 8 3 3 12 12 12 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEH15743.1 - 6.2e-11 42.6 44.1 0.028 15.0 0.1 10.7 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 CEH15743.1 - 2.7e-10 39.7 19.4 0.00027 20.5 0.1 8.5 8 1 0 9 9 9 2 TPR repeat TPR_1 PF00515.23 CEH15743.1 - 3.2e-10 39.1 0.8 0.00047 19.6 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEH15743.1 - 1.7e-08 34.7 28.0 0.64 10.3 0.0 8.0 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 CEH15743.1 - 6.9e-06 25.9 22.8 0.25 11.2 0.0 7.4 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 CEH15743.1 - 0.0013 18.4 14.1 7.5 6.6 0.3 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEH15743.1 - 0.0081 15.9 22.4 0.011 15.6 0.2 7.5 9 1 0 9 9 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEH15743.1 - 0.035 13.9 1.1 12 5.8 0.0 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 CEH15743.1 - 0.41 10.5 11.5 3.8 7.5 0.3 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEH15743.1 - 0.45 11.0 24.2 3.1 8.4 0.4 9.1 11 3 0 11 11 9 0 Tetratricopeptide repeat zf-Di19 PF05605.7 CEH15745.1 - 0.089 12.9 0.1 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Lipase_3 PF01764.20 CEH15746.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Esterase_phd PF10503.4 CEH15746.1 - 0.022 14.0 0.7 0.13 11.5 0.0 2.3 3 0 0 3 3 3 0 Esterase PHB depolymerase DUF566 PF04484.7 CEH15746.1 - 1.3 8.4 11.0 2.1 7.7 7.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 CEH15746.1 - 6.4 4.9 10.0 8.5 4.5 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein RNase_H2_suC PF08615.6 CEH15747.1 - 3.7e-22 78.6 0.0 1.1e-21 77.1 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) HORMA PF02301.13 CEH15748.1 - 3.4e-16 59.3 0.0 5.9e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 HORMA domain DUF2563 PF10817.3 CEH15749.1 - 0.032 14.6 1.1 0.041 14.3 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2563) Trp_halogenase PF04820.9 CEH15749.1 - 0.066 11.8 0.0 0.076 11.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DUF2457 PF10446.4 CEH15750.1 - 9.4 4.8 7.8 12 4.5 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LIP PF03583.9 CEH15751.1 - 1.5e-61 208.1 0.1 1.9e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 CEH15751.1 - 0.011 15.5 1.3 0.023 14.4 0.9 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family UQ_con PF00179.21 CEH15753.1 - 3.4e-45 152.9 0.0 3.8e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CEH15753.1 - 0.12 12.3 0.3 0.25 11.2 0.2 1.8 1 1 0 1 1 1 0 RWD domain CDK2AP PF09806.4 CEH15754.1 - 0.17 12.1 8.2 0.2 11.8 5.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein WD40 PF00400.27 CEH15755.1 - 6.9e-44 146.2 10.3 4.6e-08 32.6 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CEH15755.1 - 1.9e-05 24.4 0.0 0.027 14.1 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A CBS PF00571.23 CEH15756.1 - 0.0038 16.9 2.1 0.053 13.3 0.0 3.3 4 0 0 4 4 4 1 CBS domain DUF21 PF01595.15 CEH15757.1 - 2.7e-12 46.3 0.2 2.7e-12 46.3 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF21 Pkr1 PF08636.5 CEH15757.1 - 1.3 9.0 4.7 0.8 9.7 1.3 2.0 2 0 0 2 2 2 0 ER protein Pkr1 PseudoU_synth_1 PF01416.15 CEH15761.1 - 9.3e-23 80.6 0.0 2.6e-12 47.0 0.0 4.0 3 1 0 3 3 3 2 tRNA pseudouridine synthase Raffinose_syn PF05691.7 CEH15761.1 - 0.33 8.4 0.0 0.49 7.8 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 MRAP PF15183.1 CEH15762.1 - 0.3 10.7 0.1 0.3 10.7 0.1 3.0 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family PgaD PF13994.1 CEH15762.1 - 0.44 10.0 7.8 1.3 8.4 0.1 2.3 1 1 0 2 2 2 0 PgaD-like protein DUF3759 PF12585.3 CEH15763.1 - 2.4e-37 126.7 9.2 3.1e-37 126.3 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RNA_pol_Rpb2_6 PF00562.23 CEH15764.1 - 6.8e-127 423.3 0.1 1.2e-126 422.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CEH15764.1 - 5.4e-66 221.3 0.0 9.4e-66 220.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CEH15764.1 - 2.6e-42 144.4 0.0 6e-42 143.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CEH15764.1 - 3.2e-29 100.9 0.1 7e-29 99.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CEH15764.1 - 1.6e-24 85.4 0.5 4e-24 84.2 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CEH15764.1 - 5.9e-23 80.4 0.1 1.3e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CEH15764.1 - 8.2e-19 67.3 0.2 2.2e-18 65.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_S28e PF01200.13 CEH15765.1 - 5.5e-32 109.3 2.9 6e-32 109.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e zf-ZPR1 PF03367.8 CEH15765.1 - 0.15 11.2 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Ribosomal_S7 PF00177.16 CEH15766.1 - 5.4e-40 136.3 0.7 6.4e-40 136.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF3425 PF11905.3 CEH15767.1 - 2.1e-12 47.0 0.1 2.2e-10 40.5 0.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 CEH15767.1 - 9.4e-11 41.5 3.0 2.5e-10 40.1 2.0 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEH15767.1 - 0.0007 19.3 1.9 0.0021 17.8 1.3 1.8 1 0 0 1 1 1 1 Basic region leucine zipper PTH2 PF01981.11 CEH15767.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 DUF2414 PF10309.4 CEH15768.1 - 7.7e-07 28.7 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 CEH15768.1 - 0.00081 19.3 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain RRM_6 PF14259.1 CEH15768.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEH15768.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif PfkB PF00294.19 CEH15769.1 - 1.5e-57 195.0 0.2 2.6e-57 194.2 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MutS_V PF00488.16 CEH15769.1 - 2.3e-56 190.8 0.6 1.3e-54 185.0 0.0 3.5 3 1 1 4 4 4 1 MutS domain V MutS_III PF05192.13 CEH15769.1 - 2e-11 44.0 0.0 0.00015 21.6 0.0 2.4 1 1 1 2 2 2 2 MutS domain III MutS_I PF01624.15 CEH15769.1 - 6.3e-10 39.0 0.2 5.1e-09 36.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 CEH15769.1 - 4.4e-07 29.9 0.1 9.3e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV Phos_pyr_kin PF08543.7 CEH15769.1 - 0.00091 18.4 0.0 0.0022 17.2 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DEC-1_C PF04626.8 CEH15769.1 - 0.015 15.4 0.2 0.035 14.2 0.1 1.6 1 0 0 1 1 1 0 Dec-1 protein, C terminal region AAA_29 PF13555.1 CEH15769.1 - 0.051 13.1 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aldo_ket_red PF00248.16 CEH15771.1 - 2.5e-55 187.2 0.0 2.9e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CoA_binding_3 PF13727.1 CEH15772.1 - 0.051 13.3 0.4 0.1 12.4 0.3 1.5 1 0 0 1 1 1 0 CoA-binding domain DUF267 PF03268.9 CEH15772.1 - 0.4 9.4 5.8 0.26 10.1 2.3 1.8 1 1 1 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 zf-DHHC PF01529.15 CEH15772.1 - 4.3 6.6 10.1 0.45 9.8 3.5 2.0 2 1 0 2 2 2 0 DHHC palmitoyltransferase Tom5 PF10642.4 CEH15773.1 - 3.4e-12 45.7 0.0 3.8e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase TOM_sub5 PF15178.1 CEH15773.1 - 0.048 13.3 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog Hepar_II_III PF07940.8 CEH15774.1 - 7.4e-10 38.8 1.4 1.3e-09 38.0 0.2 2.1 2 0 0 2 2 2 1 Heparinase II/III-like protein Arc_PepC_II PF06847.6 CEH15774.1 - 0.14 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Ribosomal_L22e PF01776.12 CEH15776.1 - 5.2e-45 152.0 0.0 5.8e-45 151.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Cupin_8 PF13621.1 CEH15777.1 - 4.6e-35 121.3 0.0 1.8e-23 83.3 0.0 3.3 2 1 0 2 2 2 2 Cupin-like domain Cupin_4 PF08007.7 CEH15777.1 - 0.059 12.6 2.3 0.25 10.5 0.0 2.9 3 1 0 3 3 3 0 Cupin superfamily protein DIOX_N PF14226.1 CEH15778.1 - 4.1e-16 59.5 0.0 1e-15 58.2 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CEH15778.1 - 1.8e-10 40.9 0.0 3.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prenylcys_lyase PF07156.9 CEH15780.1 - 2.8e-16 59.4 0.1 7.5e-16 57.9 0.1 1.6 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 CEH15780.1 - 2.2e-06 27.5 0.1 6.4e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEH15780.1 - 0.00036 19.5 0.1 0.00055 18.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CEH15780.1 - 0.00069 19.4 0.0 0.002 17.8 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CEH15780.1 - 0.011 15.5 0.1 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEH15780.1 - 0.025 13.6 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 CEH15780.1 - 0.045 12.8 0.1 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Prenylcys_lyase PF07156.9 CEH15781.1 - 7.6e-22 77.6 0.0 3.5e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 Prenylcysteine lyase Pkinase PF00069.20 CEH15782.1 - 4.7e-65 219.3 0.0 6.2e-64 215.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15782.1 - 1.8e-34 119.0 0.0 3.3e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 CEH15782.1 - 1.1e-21 76.3 15.4 6.1e-13 48.3 6.1 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 CEH15782.1 - 5.6e-21 74.0 21.3 4.5e-11 42.2 6.0 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CEH15782.1 - 1.7e-07 31.6 0.8 4.1e-07 30.4 0.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CEH15782.1 - 0.001 18.1 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Uds1 PF15456.1 CEH15782.1 - 1.1 9.3 10.9 3.2 7.7 2.0 2.6 2 0 0 2 2 2 0 Up-regulated During Septation C1_3 PF07649.7 CEH15782.1 - 1.4 9.0 9.1 8.1 6.5 0.1 2.7 2 0 0 2 2 2 0 C1-like domain Rad17 PF03215.10 CEH15783.1 - 1.4e-45 156.0 0.0 2.1e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CEH15783.1 - 5.4e-06 26.5 0.2 4.3e-05 23.5 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CEH15783.1 - 0.00011 22.3 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH15783.1 - 0.0092 15.7 0.5 0.089 12.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 CEH15783.1 - 0.013 15.7 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 CEH15783.1 - 0.025 15.4 0.0 0.06 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain MbeB_N PF04837.7 CEH15783.1 - 0.063 13.3 0.2 6.4 6.9 0.0 2.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region AAA_18 PF13238.1 CEH15783.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CEH15783.1 - 0.17 10.7 1.6 1.9 7.3 0.0 2.8 2 1 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 CEH15783.1 - 0.22 10.3 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Cofilin_ADF PF00241.15 CEH15784.1 - 1.9e-40 137.6 0.1 2.1e-40 137.5 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Complex1_51K PF01512.12 CEH15785.1 - 3.2e-48 163.2 0.0 5.3e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CEH15785.1 - 3.3e-19 67.7 1.1 7.2e-19 66.6 0.8 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CEH15785.1 - 5.5e-08 32.5 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 SLBB domain SURF1 PF02104.10 CEH15786.1 - 1.1e-43 149.6 0.0 1.5e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 SURF1 family SNF2_N PF00176.18 CEH15787.1 - 1.1e-72 244.4 0.6 2.3e-72 243.3 0.4 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 CEH15787.1 - 1.8e-52 177.0 21.7 1.8e-52 177.0 15.0 4.7 5 0 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 CEH15787.1 - 4.3e-13 48.9 0.0 1.1e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH15787.1 - 2.8e-05 24.0 1.7 9.5e-05 22.3 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit bZIP_1 PF00170.16 CEH15789.1 - 1.7e-08 34.2 10.3 3.2e-07 30.1 4.5 2.4 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.4 CEH15789.1 - 2e-06 27.4 4.0 2e-06 27.4 2.8 2.4 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.10 CEH15789.1 - 0.0088 15.8 1.0 0.0088 15.8 0.7 3.3 3 0 0 3 3 3 2 Basic region leucine zipper Glyco_hydro_92 PF07971.7 CEH15790.1 - 7.6e-108 361.3 0.0 1.2e-107 360.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Kdo PF06293.9 CEH15791.1 - 1.5e-05 24.2 0.0 0.00016 20.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEH15791.1 - 1.6e-05 24.7 0.3 0.0017 18.1 0.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CEH15791.1 - 1.6e-05 24.1 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.15 CEH15791.1 - 0.00024 20.3 0.0 0.00052 19.2 0.0 1.3 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 CEH15791.1 - 0.0025 16.4 0.0 0.0032 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) RIO1 PF01163.17 CEH15791.1 - 0.0036 16.6 0.0 0.074 12.3 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.12 CEH15791.1 - 0.0053 15.8 0.0 0.0057 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Iron_traffic PF04362.9 CEH15791.1 - 0.094 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking SUR7 PF06687.7 CEH15793.1 - 1.9e-19 70.0 14.9 2.6e-19 69.6 10.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Rsm22 PF09243.5 CEH15794.1 - 1.2e-35 122.8 0.0 2.6e-11 43.0 0.0 4.5 4 1 0 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Troponin PF00992.15 CEH15794.1 - 0.12 12.4 5.0 0.097 12.7 1.2 2.6 2 0 0 2 2 2 0 Troponin Zn_clus PF00172.13 CEH15795.1 - 0.00022 21.0 17.4 0.00032 20.5 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-AN1 PF01428.11 CEH15797.1 - 3.2e-08 33.2 1.0 5e-08 32.6 0.7 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger zf-C2HC5 PF06221.8 CEH15797.1 - 0.068 12.9 0.4 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Pkinase PF00069.20 CEH15798.1 - 1.1e-69 234.5 0.0 1.6e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15798.1 - 1.3e-28 99.7 0.0 2.3e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CEH15798.1 - 2e-05 23.9 0.1 4.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 CEH15798.1 - 0.0005 19.1 0.2 0.33 9.8 0.0 2.4 1 1 0 2 2 2 2 Kinase-like NARP1 PF12569.3 CEH15798.1 - 2.8 6.6 6.8 4.1 6.0 4.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 WD40 PF00400.27 CEH15800.1 - 7.7e-54 177.7 18.9 5e-11 42.0 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat LisH PF08513.6 CEH15800.1 - 0.00019 21.0 1.2 0.00023 20.7 0.1 1.8 2 0 0 2 2 2 1 LisH eIF2A PF08662.6 CEH15800.1 - 0.022 14.4 0.0 0.13 11.9 0.0 2.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CEH15800.1 - 0.029 12.5 0.0 0.41 8.7 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF1751 PF08551.5 CEH15801.1 - 1.8e-23 82.7 5.1 4e-23 81.6 1.7 2.4 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 CEH15801.1 - 0.031 14.3 3.4 0.13 12.3 2.4 2.1 1 1 0 1 1 1 0 Rhomboid family Sel1 PF08238.7 CEH15802.1 - 2.9e-13 49.9 11.9 7.7e-06 26.3 0.2 6.4 6 0 0 6 6 6 3 Sel1 repeat GARS_A PF01071.14 CEH15805.1 - 2.3e-68 229.6 0.0 2.7e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 CEH15805.1 - 4.4e-07 29.7 0.0 1e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CEH15805.1 - 0.004 17.0 0.0 0.0068 16.2 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.1 CEH15805.1 - 0.015 14.3 0.0 0.061 12.4 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp CPSase_L_D2 PF02786.12 CEH15805.1 - 0.023 13.9 0.1 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 CEH15805.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain AIRS_C PF02769.17 CEH15806.1 - 5.4e-26 91.4 0.0 3.2e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CEH15806.1 - 3.2e-09 36.9 0.1 7e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Pkinase PF00069.20 CEH15807.1 - 1.4e-21 76.8 0.0 1.9e-20 73.1 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15807.1 - 1.4e-12 47.2 0.0 8.1e-12 44.7 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH15807.1 - 0.0016 17.4 0.0 0.0033 16.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like P16-Arc PF04699.9 CEH15810.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) EXOSC1 PF10447.4 CEH15811.1 - 1e-29 102.3 0.0 1.5e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 CEH15811.1 - 0.0012 18.0 0.2 0.0039 16.4 0.2 2.0 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CPSF_A PF03178.10 CEH15812.1 - 7.5e-40 136.9 0.0 1.3e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 CEH15812.1 - 6.8e-22 77.2 0.0 1.6e-21 76.0 0.0 1.6 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term HAUS-augmin3 PF14932.1 CEH15813.1 - 2.4 7.2 5.5 3.3 6.8 3.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DivIC PF04977.10 CEH15813.1 - 4.1 6.9 5.0 24 4.5 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator SH3_9 PF14604.1 CEH15814.1 - 6e-22 76.9 0.7 2.1e-10 40.0 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CEH15814.1 - 2e-19 68.7 0.2 2.3e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CEH15814.1 - 8.4e-12 44.3 0.1 5.9e-08 32.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 CEH15814.1 - 3e-11 43.3 0.1 1.3e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.6 CEH15814.1 - 0.0098 16.0 0.6 0.076 13.2 0.1 2.2 2 0 0 2 2 2 1 Bacterial SH3 domain FAD-oxidase_C PF02913.14 CEH15816.1 - 1.7e-55 188.0 0.0 2.2e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CEH15816.1 - 8e-27 93.4 2.8 1.1e-23 83.2 1.9 3.3 1 1 0 1 1 1 1 FAD binding domain SMP_2 PF10144.4 CEH15816.1 - 0.098 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin EpuA PF11772.3 CEH15816.1 - 0.14 11.6 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Glyco_hydro_20 PF00728.17 CEH15816.1 - 0.17 11.0 0.0 10 5.1 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, catalytic domain Nipped-B_C PF12830.2 CEH15817.1 - 1.6e-39 135.5 0.0 6.3e-39 133.5 0.0 2.0 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 CEH15817.1 - 3.4e-07 30.0 2.0 3.4e-07 30.0 1.4 2.2 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 CEH15817.1 - 0.00035 20.8 7.2 0.0054 16.9 3.1 3.8 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.2 CEH15817.1 - 0.0097 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CEH15817.1 - 0.034 14.2 0.5 0.7 10.1 0.1 3.5 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.1 CEH15817.1 - 0.11 12.9 8.7 0.54 10.8 2.1 4.3 4 0 0 4 4 4 0 HEAT-like repeat PAP2 PF01569.16 CEH15818.1 - 2.1e-16 59.7 3.0 3e-16 59.2 2.1 1.2 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 CEH15818.1 - 1.5e-05 24.7 0.3 0.00016 21.4 0.1 2.2 1 1 1 2 2 2 1 Divergent PAP2 family PigN PF04987.9 CEH15818.1 - 0.015 13.9 0.3 0.019 13.6 0.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) BP28CT PF08146.7 CEH15819.1 - 1e-24 87.0 0.2 5.3e-24 84.6 0.0 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 CEH15819.1 - 3.3e-10 39.9 1.8 3.3e-10 39.9 1.2 4.8 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 CEH15819.1 - 0.00018 21.2 0.9 0.0054 16.6 0.1 3.6 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.1 CEH15819.1 - 0.00048 20.3 22.3 0.0069 16.6 0.3 6.2 7 0 0 7 7 7 3 HEAT repeats Cohesin_HEAT PF12765.2 CEH15819.1 - 0.008 16.1 1.0 2.1 8.3 0.1 3.4 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 CEH15819.1 - 0.86 10.1 19.6 1 9.9 0.1 6.9 6 0 0 6 6 6 0 HEAT-like repeat Pkinase PF00069.20 CEH15821.1 - 3.7e-54 183.6 0.0 9.5e-54 182.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15821.1 - 5.2e-24 84.7 0.0 8e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH15821.1 - 0.016 14.2 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like eIF2A PF08662.6 CEH15823.1 - 5.6e-41 140.3 0.6 3.7e-18 65.9 0.0 4.8 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 CEH15823.1 - 0.0002 21.2 0.0 0.00055 19.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CEH15823.1 - 0.00034 20.3 0.5 0.56 10.1 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat YkyB PF14177.1 CEH15823.1 - 0.01 15.9 0.2 0.75 9.9 0.0 2.6 1 1 1 2 2 2 0 YkyB-like protein RRM_1 PF00076.17 CEH15823.1 - 0.012 15.2 0.1 0.073 12.7 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YtxH PF12732.2 CEH15823.1 - 1.5 9.2 3.5 1.1 9.6 0.5 2.1 2 0 0 2 2 2 0 YtxH-like protein RE_Alw26IDE PF09665.5 CEH15824.1 - 0.036 12.7 1.5 0.038 12.7 1.0 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) SPX PF03105.14 CEH15824.1 - 0.099 12.4 3.8 0.22 11.2 2.8 1.4 1 1 0 1 1 1 0 SPX domain DUF972 PF06156.8 CEH15824.1 - 0.35 11.2 2.4 0.47 10.8 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 CEH15824.1 - 0.41 9.5 4.3 0.49 9.2 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.4 CEH15824.1 - 2.1 8.1 7.1 2.7 7.7 4.9 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Homeobox PF00046.24 CEH15825.1 - 2.7e-13 49.3 0.1 6.9e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEH15825.1 - 0.00037 20.1 0.2 0.00088 18.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain HA2 PF04408.18 CEH15826.1 - 1.6e-16 60.1 0.1 4.9e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CEH15826.1 - 1.4e-13 50.5 0.1 4.2e-13 48.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEH15826.1 - 7e-11 41.9 0.1 1.4e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEH15826.1 - 3e-07 30.6 0.1 8.5e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AalphaY_MDB PF04611.7 CEH15826.1 - 0.00036 20.4 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 Mating type protein A alpha Y mating type dependent binding region AAA_19 PF13245.1 CEH15826.1 - 0.00083 19.0 0.0 0.0032 17.1 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 CEH15826.1 - 0.003 16.7 0.0 0.0057 15.7 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SE PF00437.15 CEH15826.1 - 0.016 14.1 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein OB_NTP_bind PF07717.11 CEH15826.1 - 0.042 13.6 0.0 0.42 10.4 0.0 2.4 1 1 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 CEH15826.1 - 0.047 13.2 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CEH15826.1 - 0.052 13.8 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CEH15826.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Sec5 PF15469.1 CEH15828.1 - 6e-20 71.7 0.1 1.1e-19 70.8 0.1 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 CENP-H PF05837.7 CEH15828.1 - 0.011 15.9 0.4 9.2 6.4 0.0 2.8 2 1 0 2 2 2 0 Centromere protein H (CENP-H) RuvA_C PF07499.8 CEH15829.1 - 0.034 14.2 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 RuvA, C-terminal domain UPF0061 PF02696.9 CEH15830.1 - 1.3e-87 294.1 0.2 2.3e-79 266.9 0.0 2.0 1 1 1 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family PSD4 PF07631.6 CEH15830.1 - 0.037 14.4 3.9 5.5 7.3 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1592) RNA_polI_A14 PF08203.6 CEH15831.1 - 0.012 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 DUF1180 PF06679.7 CEH15832.1 - 9.1 6.1 21.9 0.2 11.5 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Pkinase PF00069.20 CEH15833.1 - 2.2e-67 226.9 0.0 3.2e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15833.1 - 8.2e-47 159.4 0.0 1.3e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH15833.1 - 0.0013 17.7 0.0 0.0032 16.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Arm PF00514.18 CEH15833.1 - 0.092 12.6 0.2 46 4.0 0.0 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Na_H_Exchanger PF00999.16 CEH15835.1 - 1.5e-45 155.3 14.9 2.1e-45 154.8 10.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 CEH15835.1 - 0.0011 18.8 2.1 0.0016 18.3 0.1 2.3 2 0 0 2 2 2 1 YrhC-like protein NAD_binding_3 PF03447.11 CEH15836.1 - 0.0035 17.7 0.1 0.0079 16.5 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CEH15836.1 - 0.0066 15.1 0.0 0.014 14.1 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CEH15836.1 - 0.0066 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family ApbA PF02558.11 CEH15836.1 - 0.026 13.9 0.0 0.069 12.5 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 CEH15836.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain PPR_2 PF13041.1 CEH15837.1 - 0.0034 17.3 0.0 5.8 6.9 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family Solute_trans_a PF03619.11 CEH15841.1 - 9.4e-72 241.6 16.4 1.1e-71 241.3 11.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4396 PF14342.1 CEH15841.1 - 7.3 6.6 12.9 0.11 12.6 0.5 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4396) RRM_6 PF14259.1 CEH15842.1 - 1.9e-08 34.1 0.0 3.4e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEH15842.1 - 1.1e-05 24.9 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH15842.1 - 0.00048 19.9 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAP1_N PF04849.8 CEH15845.1 - 0.006 15.5 0.4 0.014 14.3 0.3 1.5 1 0 0 1 1 1 1 HAP1 N-terminal conserved region TSC22 PF01166.13 CEH15845.1 - 0.014 15.3 1.5 0.021 14.8 0.0 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family PAT1 PF09770.4 CEH15845.1 - 1.3 7.2 41.9 1.1 7.3 23.2 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MAD PF05557.8 CEH15845.1 - 1.5 6.7 11.3 0.077 11.0 0.3 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein YdfA_immunity PF12127.3 CEH15845.1 - 6.1 5.6 5.6 16 4.3 1.8 2.2 2 0 0 2 2 2 0 SigmaW regulon antibacterial PCI PF01399.22 CEH15846.1 - 4.2e-18 65.5 0.3 9.1e-18 64.5 0.2 1.6 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 CEH15846.1 - 5.7e-11 42.3 0.3 1.1e-10 41.4 0.2 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 CEH15846.1 - 0.00043 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 FeoC like transcriptional regulator SAC3_GANP PF03399.11 CEH15846.1 - 0.039 13.5 0.2 0.087 12.3 0.1 1.7 1 1 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TPR_7 PF13176.1 CEH15846.1 - 0.21 11.4 1.3 21 5.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-CCCH_2 PF14608.1 CEH15847.1 - 1.1e-08 34.7 21.9 3.4e-06 26.8 5.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 CEH15847.1 - 3.8e-08 32.8 13.9 0.00014 21.4 2.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_2 PF12796.2 CEH15847.1 - 3.4e-06 27.2 0.2 6.1e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEH15847.1 - 0.00012 22.4 0.1 0.0081 16.6 0.0 2.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CEH15847.1 - 0.00013 21.6 0.1 0.00031 20.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 CEH15847.1 - 0.00016 21.7 0.0 0.00038 20.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH15847.1 - 0.013 15.6 0.0 0.038 14.2 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat WD40 PF00400.27 CEH15848.1 - 2.7e-25 87.2 17.5 7.2e-07 28.8 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat PmrD PF11183.3 CEH15848.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD Nucleoporin_N PF08801.6 CEH15848.1 - 0.047 12.4 0.3 1.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like C1_2 PF03107.11 CEH15848.1 - 0.099 12.7 3.9 0.19 11.8 2.7 1.5 1 0 0 1 1 1 0 C1 domain Pyr_redox_3 PF13738.1 CEH15853.1 - 4.4e-24 85.6 0.0 8.3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CEH15853.1 - 3.9e-08 31.9 0.1 1.3e-07 30.2 0.2 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CEH15853.1 - 7.8e-08 31.6 0.0 3.7e-06 26.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CEH15853.1 - 9.7e-08 31.9 0.0 2.3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CEH15853.1 - 4e-06 26.8 0.0 0.00079 19.3 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEH15853.1 - 0.0054 15.6 1.1 2.8 6.7 0.0 3.0 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 CEH15853.1 - 0.012 15.4 0.0 0.41 10.4 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 CEH15853.1 - 0.026 13.4 0.0 0.27 10.1 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase RPAP3_C PF13877.1 CEH15854.1 - 8.4e-10 38.5 0.1 2e-09 37.2 0.1 1.7 1 1 0 1 1 1 1 Potential Monad-binding region of RPAP3 FHA PF00498.21 CEH15855.1 - 0.0024 17.9 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain SCF PF02404.10 CEH15856.1 - 0.015 14.4 0.5 0.017 14.3 0.3 1.1 1 0 0 1 1 1 0 Stem cell factor Transglut_C PF00927.17 CEH15856.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.0 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain DEAD PF00270.24 CEH15858.1 - 3.7e-33 114.4 0.2 1.2e-32 112.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH15858.1 - 9.8e-26 89.4 0.1 1.9e-25 88.5 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TPR_19 PF14559.1 CEH15859.1 - 0.0037 17.5 1.0 0.0069 16.7 0.7 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat E2_bind PF08825.5 CEH15859.1 - 0.019 14.6 0.2 0.033 13.9 0.2 1.4 1 0 0 1 1 1 0 E2 binding domain Apc3 PF12895.2 CEH15859.1 - 0.027 14.5 2.9 0.042 14.0 2.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 CEH15859.1 - 0.11 12.1 3.6 0.22 11.1 2.5 1.6 1 0 0 1 1 1 0 TPR repeat NESP55 PF06390.7 CEH15859.1 - 0.76 9.1 5.3 0.28 10.5 0.5 1.9 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) SQS_PSY PF00494.14 CEH15860.1 - 1.3e-32 113.1 0.0 2.8e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 Squalene/phytoene synthase NAD_binding_8 PF13450.1 CEH15861.1 - 1e-09 38.2 0.2 3.8e-09 36.4 0.1 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CEH15861.1 - 1.6e-05 24.2 0.1 0.024 13.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 CEH15861.1 - 0.00018 20.5 0.2 0.00018 20.5 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CEH15861.1 - 0.0014 17.7 0.4 0.0024 16.9 0.3 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 CEH15861.1 - 0.0033 17.2 0.8 0.0069 16.1 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 CEH15861.1 - 0.016 15.6 0.4 0.055 13.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEH15861.1 - 0.029 13.4 0.5 0.072 12.1 0.4 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEH15861.1 - 0.035 12.9 0.7 0.059 12.2 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain Aldo_ket_red PF00248.16 CEH15862.1 - 9.5e-38 129.6 0.0 1.3e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DDHD PF02862.12 CEH15863.1 - 1.6e-34 119.7 3.0 1.4e-33 116.5 0.0 2.9 2 2 0 2 2 2 1 DDHD domain Abhydrolase_6 PF12697.2 CEH15863.1 - 0.00036 20.5 0.4 0.0011 18.8 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cellulase PF00150.13 CEH15864.1 - 1.4e-08 34.2 0.2 1.9e-07 30.5 0.2 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 CEH15864.1 - 1.2e-05 25.6 1.1 0.00026 21.3 0.1 2.7 1 1 1 2 2 2 1 Sugar-binding cellulase-like Got1 PF04178.7 CEH15865.1 - 7.9e-17 61.4 23.0 1.1e-16 61.0 15.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family SEN1_N PF12726.2 CEH15866.1 - 2.5e-49 168.0 0.1 2e-35 122.0 0.1 3.1 3 0 0 3 3 3 3 SEN1 N terminal AAA_11 PF13086.1 CEH15866.1 - 2.1e-46 158.4 1.4 1.4e-37 129.5 0.2 2.5 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.1 CEH15866.1 - 1.9e-24 86.1 0.1 2.3e-18 66.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 CEH15866.1 - 1.7e-08 34.2 1.1 4.5e-08 32.9 0.8 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH15866.1 - 4.4e-08 32.7 0.2 1.7e-07 30.8 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CEH15866.1 - 2.7e-05 23.7 0.3 0.012 15.1 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CEH15866.1 - 0.011 15.0 0.0 0.46 9.7 0.0 2.3 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 CEH15866.1 - 0.047 13.8 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CEH15866.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CEH15866.1 - 0.18 10.7 0.0 0.59 9.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CEH15866.1 - 0.19 11.8 2.1 0.95 9.6 0.3 2.9 3 1 0 3 3 3 0 AAA domain Melibiase PF02065.13 CEH15867.1 - 2.4e-11 42.9 0.3 9.7e-07 27.8 0.0 2.6 2 1 0 2 2 2 2 Melibiase CBM_6 PF03422.10 CEH15867.1 - 0.004 17.3 1.6 0.01 15.9 1.1 1.8 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Glyco_hydro_97 PF10566.4 CEH15867.1 - 0.087 11.9 0.0 12 4.8 0.0 2.2 2 0 0 2 2 2 0 Glycoside hydrolase 97 Mago_nashi PF02792.9 CEH15868.1 - 4e-40 136.8 0.1 4.4e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.15 CEH15869.1 - 1.9e-110 369.6 0.0 2.7e-110 369.1 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CEH15869.1 - 2.9e-52 176.4 0.9 6e-52 175.4 0.6 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CEH15869.1 - 5.4e-16 58.6 8.4 7.9e-05 22.8 0.2 7.2 3 2 5 8 8 8 5 HEAT repeats HEAT PF02985.17 CEH15869.1 - 4.4e-07 29.4 4.9 1.4 9.2 0.2 6.2 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 CEH15869.1 - 0.0081 16.0 7.0 0.89 9.3 0.1 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 BID PF06393.6 CEH15869.1 - 0.04 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 BH3 interacting domain (BID) HEAT_PBS PF03130.11 CEH15869.1 - 3.5 8.3 17.3 1.4 9.5 0.2 6.1 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat PPR_2 PF13041.1 CEH15870.1 - 0.00081 19.3 0.0 2.5 8.1 0.1 2.8 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 CEH15870.1 - 3.3 8.2 5.7 4 7.9 0.0 3.8 4 0 0 4 4 4 0 Pentatricopeptide repeat domain GATA PF00320.22 CEH15871.1 - 2.5e-14 52.3 3.5 7e-14 50.8 2.5 1.8 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.2 CEH15871.1 - 0.13 12.1 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon CtaG_Cox11 PF04442.9 CEH15872.1 - 7e-52 175.2 0.0 9.3e-52 174.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DnaJ_CXXCXGXG PF00684.14 CEH15873.1 - 0.0089 16.0 9.9 0.53 10.3 0.4 2.6 2 0 0 2 2 2 2 DnaJ central domain MHC_I_C PF06623.6 CEH15878.1 - 0.06 12.8 0.3 0.089 12.2 0.2 1.3 1 0 0 1 1 1 0 MHC_I C-terminus Bacillus_PapR PF05968.6 CEH15880.1 - 0.16 12.0 0.0 2.5 8.2 0.0 2.5 3 0 0 3 3 3 0 Bacillus PapR protein Mating_N PF12731.2 CEH15881.1 - 0.0049 16.7 0.1 0.006 16.4 0.1 1.1 1 0 0 1 1 1 1 Mating-type protein beta 1 HLH PF00010.21 CEH15882.1 - 2.4e-09 36.7 0.0 6.4e-09 35.3 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Gly-zipper_OmpA PF13436.1 CEH15882.1 - 0.22 11.1 7.6 0.18 11.4 4.0 1.8 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain MCM2_N PF12619.3 CEH15882.1 - 4.7 7.1 12.2 9.7 6.1 8.5 1.5 1 1 0 1 1 1 0 Mini-chromosome maintenance protein 2 Fcf2 PF08698.6 CEH15883.1 - 5.4e-15 55.2 0.0 4.3e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing MFS_1 PF07690.11 CEH15885.1 - 3.7e-23 81.7 38.1 2.8e-22 78.9 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1295 PF06966.7 CEH15887.1 - 5.9e-43 146.8 0.3 5.7e-42 143.6 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CEH15887.1 - 0.0053 16.9 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CEH15887.1 - 0.048 13.7 0.3 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Phospholipid methyltransferase adh_short PF00106.20 CEH15888.1 - 4.3e-29 101.5 2.7 5.7e-29 101.1 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH15888.1 - 1.2e-23 84.1 0.2 2.2e-23 83.2 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH15888.1 - 6.2e-12 45.5 1.4 9.2e-12 44.9 1.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CEH15888.1 - 0.052 13.2 0.7 0.084 12.5 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CEH15888.1 - 0.16 11.3 0.3 0.48 9.7 0.3 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2341 PF10102.4 CEH15889.1 - 0.011 15.8 1.2 0.013 15.6 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) WSC PF01822.14 CEH15889.1 - 0.12 12.3 0.7 0.16 11.9 0.5 1.3 1 1 0 1 1 1 0 WSC domain DUF4430 PF14478.1 CEH15891.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Mucin PF01456.12 CEH15891.1 - 0.12 12.1 49.6 0.053 13.2 10.7 2.9 3 0 0 3 3 3 0 Mucin-like glycoprotein Hist_deacetyl PF00850.14 CEH15892.1 - 1e-53 182.6 0.8 1.4e-53 182.2 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain RVT_1 PF00078.22 CEH15898.1 - 4.1e-37 127.6 0.1 2.4e-19 69.5 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CEH15898.1 - 6.3e-12 44.9 0.0 1.4e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CEH15898.1 - 1e-08 35.2 0.0 3e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain KxDL PF10241.4 CEH15898.1 - 0.0017 18.2 1.0 0.63 9.9 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein UBN2_2 PF14227.1 CEH15898.1 - 0.0023 17.4 0.1 2.6 7.6 0.0 2.3 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type Asp_protease_2 PF13650.1 CEH15898.1 - 0.014 15.8 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_2 PF07727.9 CEH15898.1 - 0.064 12.2 0.2 31 3.4 0.0 3.6 4 0 0 4 4 4 0 Reverse transcriptase (RNA-dependent DNA polymerase) 7TM_GPCR_Srsx PF10320.4 CEH15898.1 - 0.066 12.3 0.1 5.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx Mtf2_C PF14061.1 CEH15898.1 - 0.12 12.2 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DUF4325 PF14213.1 CEH15898.1 - 0.15 11.6 3.3 6.2 6.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4325) zf-CCHC PF00098.18 CEH15899.1 - 1.1e-05 25.1 0.9 2.5e-05 23.9 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 CEH15899.1 - 4.6e-05 22.8 0.2 4.6e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.12 CEH15899.1 - 0.0055 16.7 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 CEH15899.1 - 0.086 12.5 0.6 0.22 11.3 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CEH15899.1 - 0.15 11.7 0.6 0.26 10.9 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 CEH15899.1 - 2.1 8.0 5.0 2.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle Cys_Met_Meta_PP PF01053.15 CEH15901.1 - 4.6e-28 97.6 0.0 8.4e-20 70.3 0.0 2.4 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CEH15901.1 - 0.001 18.0 0.0 0.0024 16.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II adh_short PF00106.20 CEH15902.1 - 1.7e-17 63.8 0.3 2.6e-17 63.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH15902.1 - 3.8e-09 36.4 0.4 6.7e-09 35.6 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CEH15902.1 - 1.9e-08 34.3 0.1 2.9e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CEH15902.1 - 2.5e-05 23.8 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEH15902.1 - 0.0017 18.4 0.4 0.0052 16.7 0.3 2.0 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 CEH15902.1 - 0.024 13.6 0.3 0.056 12.4 0.2 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Glyco_transf_9 PF01075.12 CEH15902.1 - 0.082 12.1 2.5 0.058 12.6 0.5 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 9 (heptosyltransferase) YjeF_N PF03853.10 CEH15902.1 - 0.12 11.9 0.9 0.42 10.1 0.1 2.1 3 0 0 3 3 3 0 YjeF-related protein N-terminus MBOAT PF03062.14 CEH15903.1 - 1.5e-35 122.8 7.5 1.5e-35 122.8 5.2 1.8 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CEH15903.1 - 0.00052 20.0 1.1 0.0014 18.6 0.8 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ribosomal_L24e PF01246.15 CEH15904.1 - 1.1e-17 63.6 2.6 1.1e-17 63.6 1.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e DUF3179 PF11376.3 CEH15904.1 - 0.049 12.7 0.8 0.058 12.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) ATP-synt_ab PF00006.20 CEH15905.1 - 2.5e-70 236.3 0.0 3.8e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEH15905.1 - 1.3e-21 77.1 0.0 3e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEH15905.1 - 9.4e-21 73.8 1.7 2.1e-20 72.7 1.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CEH15905.1 - 7.3e-06 25.7 1.1 1.5e-05 24.7 0.7 1.6 1 0 0 1 1 1 1 HAS barrel domain TPR_1 PF00515.23 CEH15906.1 - 8.3e-27 91.6 15.5 6.3e-05 22.4 0.0 6.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 CEH15906.1 - 1.4e-23 80.8 17.8 0.00043 19.9 0.0 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 CEH15906.1 - 3.9e-23 80.8 19.0 6.4e-12 44.9 0.2 5.8 4 1 2 6 6 6 4 TPR repeat TPR_17 PF13431.1 CEH15906.1 - 3e-15 55.0 2.6 0.001 19.0 0.1 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat APC8 PF04049.8 CEH15906.1 - 1.4e-14 54.0 0.0 3e-08 33.4 0.0 2.7 2 0 0 2 2 2 2 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.1 CEH15906.1 - 2.2e-14 52.0 3.4 0.00022 20.7 0.0 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEH15906.1 - 1.5e-12 46.3 4.9 0.01 15.5 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEH15906.1 - 1.7e-12 47.6 24.5 0.00012 22.5 1.0 7.8 7 1 2 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 CEH15906.1 - 2.4e-12 46.3 17.3 6.5e-06 26.3 0.6 8.8 8 2 1 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEH15906.1 - 5.8e-11 42.1 15.0 1.6e-05 24.7 0.8 5.9 3 2 4 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 CEH15906.1 - 5.3e-10 39.2 11.7 4.9e-06 26.5 1.5 4.7 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CEH15906.1 - 6.4e-10 39.2 2.0 0.00011 22.4 0.0 5.0 4 1 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CEH15906.1 - 4.9e-08 32.3 1.4 0.0003 19.9 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEH15906.1 - 1.9e-05 24.4 14.1 0.0065 16.2 1.2 4.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEH15906.1 - 2.5e-05 24.4 4.5 0.89 10.1 0.0 7.2 7 1 1 8 8 8 1 Tetratricopeptide repeat ChAPs PF09295.5 CEH15906.1 - 0.00035 19.4 0.0 0.006 15.4 0.0 2.7 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.12 CEH15906.1 - 0.41 10.9 8.2 0.63 10.3 0.9 3.1 3 0 0 3 3 3 0 Bacterial transcriptional activator domain AMP-binding PF00501.23 CEH15907.1 - 2.3e-77 260.1 0.0 3.1e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEH15907.1 - 7.3e-17 62.0 0.3 1.6e-16 60.9 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BAG PF02179.11 CEH15911.1 - 2.6e-14 53.1 0.0 3.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 CEH15911.1 - 4e-07 29.3 0.0 6.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family SRA1 PF07304.6 CEH15911.1 - 0.016 14.9 0.2 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Cyto_heme_lyase PF01265.12 CEH15912.1 - 4.8e-65 219.7 0.1 6.2e-65 219.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase BNR PF02012.15 CEH15914.1 - 0.05 13.4 47.4 0.29 11.1 0.4 11.0 12 0 0 12 12 12 0 BNR/Asp-box repeat Fe_dep_repr_C PF02742.10 CEH15914.1 - 0.066 12.9 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain UCR_UQCRX_QCR9 PF05365.7 CEH15914.1 - 0.13 11.9 0.2 17 5.1 0.0 3.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like SH3_9 PF14604.1 CEH15916.1 - 1.4e-42 143.0 7.0 4.1e-15 55.1 0.1 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 CEH15916.1 - 4.5e-42 141.2 6.6 1.1e-15 56.7 0.1 4.0 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 CEH15916.1 - 2.1e-32 110.5 0.0 4.2e-32 109.6 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 CEH15916.1 - 3.6e-23 80.7 0.0 8.3e-06 25.2 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain DUF1720 PF08226.6 CEH15916.1 - 2.2e-07 30.8 88.4 0.00045 20.2 30.0 4.5 1 1 1 3 3 3 3 Domain of unknown function (DUF1720) SH3_3 PF08239.6 CEH15916.1 - 5.8e-06 26.4 2.1 0.0055 16.8 0.1 3.6 3 0 0 3 3 3 2 Bacterial SH3 domain zf-RING_2 PF13639.1 CEH15917.1 - 1.4e-09 37.5 7.9 3.2e-09 36.4 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CEH15917.1 - 4.4e-07 29.5 8.3 8.4e-07 28.6 5.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CEH15917.1 - 3.2e-06 27.1 6.5 8.4e-06 25.8 4.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CEH15917.1 - 4.9e-05 22.9 5.7 0.00012 21.7 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger BBP1_C PF15272.1 CEH15917.1 - 6.3e-05 22.6 5.7 6.3e-05 22.6 3.9 2.6 2 1 2 4 4 2 1 Spindle pole body component BBP1, C-terminal zf-C3HC4 PF00097.20 CEH15917.1 - 6.5e-05 22.5 8.0 0.00014 21.4 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH15917.1 - 8.4e-05 22.5 8.3 0.00018 21.4 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CEH15917.1 - 0.00066 19.4 6.2 0.0021 17.8 4.3 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CEH15917.1 - 0.0024 17.8 0.9 0.0024 17.8 0.6 1.9 2 0 0 2 2 2 1 FANCL C-terminal domain zf-Apc11 PF12861.2 CEH15917.1 - 0.06 13.1 4.6 0.13 12.1 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3508 PF12018.3 CEH15917.1 - 3.7 6.4 12.4 0.027 13.4 1.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3508) APG6 PF04111.7 CEH15917.1 - 8.9 5.2 34.6 2.2 7.2 10.4 2.7 1 1 2 3 3 3 0 Autophagy protein Apg6 WD40 PF00400.27 CEH15918.1 - 5.8e-33 111.5 26.3 1.1e-08 34.5 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Hira PF07569.6 CEH15918.1 - 3.6e-31 108.0 0.0 7.5e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split HIRA_B PF09453.5 CEH15918.1 - 5.6e-05 22.5 0.3 0.00015 21.1 0.2 1.8 1 0 0 1 1 1 1 HIRA B motif Nup160 PF11715.3 CEH15918.1 - 0.0068 14.5 0.1 1 7.3 0.1 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Vezatin PF12632.2 CEH15919.1 - 3.1e-12 46.1 0.2 1.2e-06 27.8 0.0 3.2 2 1 1 3 3 3 3 Mysoin-binding motif of peroxisomes DUF2306 PF10067.4 CEH15920.1 - 2.3e-06 27.6 9.9 6.8e-06 26.1 4.2 3.1 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) PepSY_TM_2 PF13703.1 CEH15920.1 - 7.6 6.7 17.4 2.2 8.5 0.6 2.9 2 1 1 3 3 3 0 PepSY-associated TM helix Glyco_hydro_18 PF00704.23 CEH15922.1 - 1.1e-07 31.7 0.0 2.2e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Ribosomal_L18e PF00828.14 CEH15923.1 - 6.6e-34 117.0 0.1 8.2e-34 116.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 zf-RING_5 PF14634.1 CEH15924.1 - 8.5e-06 25.3 8.3 1.2e-05 24.9 2.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain DUF2296 PF10058.4 CEH15924.1 - 0.08 12.6 0.8 0.15 11.8 0.6 1.4 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) DUF1664 PF07889.7 CEH15924.1 - 0.099 12.4 0.1 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 CEH15925.1 - 0.054 13.2 2.2 0.1 12.3 1.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MUG113 PF13455.1 CEH15926.1 - 1.1e-14 54.6 0.0 3e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 CEH15926.1 - 5.4e-07 29.9 0.1 3.1e-06 27.5 0.0 2.3 3 0 0 3 3 3 1 T5orf172 domain zf-primase PF09329.6 CEH15926.1 - 0.011 15.2 2.5 0.14 11.7 0.1 2.4 2 0 0 2 2 2 0 Primase zinc finger SmpA_OmlA PF04355.8 CEH15926.1 - 0.045 13.3 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 SmpA / OmlA family DUF1777 PF08648.7 CEH15927.1 - 3.9e-20 72.3 62.3 1.5e-17 63.8 43.2 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CEH15927.1 - 3.1 6.1 19.4 3.5 5.9 13.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PIF1 PF05970.9 CEH15928.1 - 1.6e-55 188.5 0.2 7.3e-48 163.3 0.2 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CEH15928.1 - 5.3e-17 62.0 0.0 1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEH15928.1 - 4.2e-06 26.9 0.0 8.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 CEH15928.1 - 9.3e-05 22.5 0.0 0.0009 19.3 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 CEH15928.1 - 0.00011 20.1 1.3 0.01 13.6 0.0 2.2 2 0 0 2 2 2 2 Helicase AAA_16 PF13191.1 CEH15928.1 - 0.0003 20.8 0.0 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CEH15928.1 - 0.00097 18.8 0.2 0.0029 17.3 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CEH15928.1 - 0.0017 18.2 0.0 0.29 11.0 0.0 3.2 1 1 1 2 2 2 1 AAA domain PhoH PF02562.11 CEH15928.1 - 0.0059 15.8 0.1 0.11 11.6 0.0 2.4 2 1 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.4 CEH15928.1 - 0.0071 15.3 0.5 0.13 11.1 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 CEH15928.1 - 0.0078 15.9 0.2 0.18 11.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 CEH15928.1 - 0.033 13.7 0.1 1.9 7.9 0.0 2.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 CEH15928.1 - 0.037 14.3 0.0 0.18 12.1 0.0 2.2 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 CEH15928.1 - 0.044 13.4 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 CEH15928.1 - 0.055 12.0 0.1 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 CEH15928.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 CEH15928.1 - 0.089 12.9 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 CEH15930.1 - 4.4e-42 144.0 0.0 6.4e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH15930.1 - 9e-15 54.4 0.0 1.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH15930.1 - 0.00029 20.6 0.1 0.0047 16.6 0.0 2.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CEH15930.1 - 0.0023 17.2 0.0 0.0057 16.0 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 CEH15930.1 - 0.0066 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PGP_phosphatase PF09419.5 CEH15930.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase RAM PF15320.1 CEH15933.1 - 0.06 13.6 0.0 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Histone PF00125.19 CEH15934.1 - 6.3e-13 48.6 0.0 7.9e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CEH15934.1 - 9.9e-05 22.3 0.0 0.00016 21.6 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CEH15934.1 - 0.00041 20.4 0.0 0.00053 20.1 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CEH15934.1 - 0.00046 20.0 0.1 0.00066 19.5 0.0 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 CEH15934.1 - 0.0059 15.8 0.0 0.0064 15.7 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T MS_channel PF00924.13 CEH15935.1 - 1.6e-16 60.2 2.0 1.6e-16 60.2 1.4 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CEH15935.1 - 6.2e-05 22.0 0.2 0.00015 20.8 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CEH15935.1 - 0.00011 21.7 0.1 0.0003 20.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CEH15935.1 - 0.046 13.0 0.4 0.1 12.0 0.3 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 CEH15935.1 - 0.076 13.1 0.1 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain pair DUF3948 PF13134.1 CEH15935.1 - 7.9 6.0 14.0 11 5.5 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) LIM PF00412.17 CEH15937.1 - 1.9e-20 72.6 22.8 6.9e-13 48.4 2.2 4.7 5 0 0 5 5 5 3 LIM domain zf-C2H2 PF00096.21 CEH15937.1 - 3 8.3 7.6 19 5.8 0.2 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Mu-like_Com PF10122.4 CEH15937.1 - 8.1 5.5 7.9 5.2 6.1 0.2 3.1 3 0 0 3 3 3 0 Mu-like prophage protein Com RhoGAP PF00620.22 CEH15938.1 - 5.3e-37 126.7 0.1 8.6e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Ribophorin_II PF05817.9 CEH15940.1 - 3.4e-08 32.2 0.0 4.4e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Sua5_yciO_yrdC PF01300.13 CEH15941.1 - 0.029 13.6 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Telomere recombination Nup35_RRM_2 PF14605.1 CEH15941.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nol1_Nop2_Fmu PF01189.12 CEH15942.1 - 1.2e-30 106.8 0.0 4.5e-26 91.8 0.0 3.3 2 1 0 2 2 2 2 NOL1/NOP2/sun family DUF4448 PF14610.1 CEH15945.1 - 8.3e-13 48.2 0.0 1.7e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 CEH15945.1 - 0.016 15.6 0.7 0.029 14.8 0.5 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MFS_1 PF07690.11 CEH15946.1 - 8.7e-30 103.6 24.6 2.5e-29 102.1 17.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1003 PF06210.6 CEH15946.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) TPR_11 PF13414.1 CEH15947.1 - 2.3e-45 152.1 22.0 3.1e-18 65.1 1.9 5.6 3 3 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 CEH15947.1 - 1.5e-25 87.7 19.8 9.4e-05 21.8 0.1 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 CEH15947.1 - 4e-25 85.6 20.3 0.0012 18.5 0.4 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.26 CEH15947.1 - 2.6e-22 78.2 3.2 6e-22 77.1 1.3 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.1 CEH15947.1 - 4.9e-19 68.4 24.4 1.9e-07 31.5 0.4 6.7 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.1 CEH15947.1 - 2.4e-17 63.0 20.9 7.2e-05 23.0 0.5 6.5 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 CEH15947.1 - 5.6e-15 55.0 21.7 2.3e-06 27.4 0.4 5.8 2 2 4 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 CEH15947.1 - 2.8e-14 53.0 10.6 3.8e-08 33.3 0.7 3.7 2 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CEH15947.1 - 7.7e-13 47.8 23.1 0.0013 19.1 0.1 8.2 5 3 4 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 CEH15947.1 - 2.2e-11 43.0 11.1 0.014 15.5 0.2 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEH15947.1 - 5.6e-11 41.3 10.2 0.033 13.9 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 CEH15947.1 - 1.9e-09 37.3 10.5 0.24 11.9 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEH15947.1 - 3.7e-08 33.0 13.0 0.036 13.9 0.2 5.4 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 CEH15947.1 - 8.1e-07 28.3 16.9 0.69 9.8 0.4 8.0 7 1 1 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEH15947.1 - 0.0019 18.0 13.2 0.067 13.0 0.2 5.2 5 1 2 7 7 5 2 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 CEH15947.1 - 0.0034 17.2 17.3 0.16 11.8 1.0 4.7 2 1 0 3 3 3 2 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 CEH15947.1 - 0.0051 16.6 1.1 0.0051 16.6 0.8 4.0 3 1 1 4 4 4 1 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.4 CEH15947.1 - 0.011 15.0 6.9 0.04 13.1 0.1 3.5 4 0 0 4 4 3 0 SHNi-TPR ChAPs PF09295.5 CEH15947.1 - 0.051 12.3 0.4 1.3 7.6 0.0 2.6 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR_3 PF13812.1 CEH15947.1 - 0.092 13.0 0.0 7.1 7.1 0.0 3.7 4 0 0 4 4 3 0 Pentatricopeptide repeat domain Musclin PF11037.3 CEH15947.1 - 0.12 11.9 0.4 0.3 10.6 0.3 1.6 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle DUF327 PF03885.8 CEH15947.1 - 0.58 9.9 4.2 0.42 10.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Alkyl_sulf_dimr PF14863.1 CEH15947.1 - 4.3 7.5 13.5 3.4 7.8 0.7 4.4 1 1 1 5 5 5 0 Alkyl sulfatase dimerisation TPR_4 PF07721.9 CEH15947.1 - 7.3 7.3 11.7 9.3 7.0 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF982 PF06169.7 CEH15947.1 - 8.1 6.2 13.2 0.13 11.9 0.6 3.9 4 1 1 5 5 4 0 Protein of unknown function (DUF982) DUF4363 PF14276.1 CEH15947.1 - 8.4 6.1 7.7 16 5.2 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) Adenylsucc_synt PF00709.16 CEH15948.1 - 1.5e-160 534.4 0.0 1.8e-160 534.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MIF4G PF02854.14 CEH15949.1 - 7.1e-12 45.1 0.0 1.8e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CEH15949.1 - 1.7e-11 43.8 0.0 3.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 MA3 domain Abhydrolase_6 PF12697.2 CEH15950.1 - 5e-07 29.8 0.1 6.2e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH15950.1 - 5e-06 26.3 0.0 7.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CEH15950.1 - 0.0035 16.6 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 CEH15950.1 - 0.087 12.3 0.1 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 CEH15950.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.8 CEH15950.1 - 0.13 11.8 0.7 0.47 9.9 0.0 2.2 3 0 0 3 3 3 0 PGAP1-like protein NAD_binding_2 PF03446.10 CEH15951.1 - 3e-31 108.4 0.0 5.6e-31 107.5 0.0 1.4 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CEH15951.1 - 4.9e-31 107.3 0.0 8e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF3608 PF12257.3 CEH15952.1 - 6.7e-69 231.8 0.0 2.3e-68 230.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 CEH15952.1 - 8.7e-20 70.2 0.2 1.9e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP_transf PF09830.4 CEH15953.1 - 1.8e-15 56.4 0.0 3.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase Sec15 PF04091.7 CEH15954.1 - 1.7e-74 250.9 0.0 3.7e-74 249.8 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.9 CEH15954.1 - 1e-06 28.4 0.8 6.3e-06 25.8 0.1 2.6 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 CEH15954.1 - 5.3e-05 23.0 3.7 5.6e-05 23.0 0.4 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 CEH15954.1 - 0.00033 20.6 3.6 0.00035 20.5 0.1 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.6 CEH15954.1 - 0.0018 18.0 1.5 0.042 13.6 0.0 3.2 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.1 CEH15954.1 - 0.0051 16.5 0.4 0.027 14.2 0.0 2.4 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps53_N PF04100.7 CEH15954.1 - 0.077 11.7 1.6 0.17 10.6 0.0 2.2 3 0 0 3 3 3 0 Vps53-like, N-terminal ArfGap PF01412.13 CEH15955.1 - 1.2e-31 108.9 0.0 2.6e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf LMWSLP_N PF12211.3 CEH15955.1 - 4.4 7.0 10.0 1.2 8.9 1.8 2.6 3 0 0 3 3 3 0 Low molecular weight S layer protein N terminal tRNA-synt_1e PF01406.14 CEH15956.1 - 6.1e-122 406.4 0.0 1.5e-121 405.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CEH15956.1 - 2.6e-09 36.2 0.2 2.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CEH15956.1 - 0.00058 17.9 0.2 0.028 12.4 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 CEH15956.1 - 0.0016 18.6 1.2 0.0067 16.6 0.0 2.8 3 0 0 3 3 3 1 DALR domain WD40 PF00400.27 CEH15957.1 - 8.7e-15 53.9 5.2 3.1e-05 23.6 0.1 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat Fungal_trans PF04082.13 CEH15958.1 - 5.7e-14 51.6 0.1 8.7e-14 51.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH15958.1 - 0.00057 19.7 14.9 0.00099 18.9 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2290 PF10053.4 CEH15959.1 - 0.081 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2290) Helicase_C_3 PF13625.1 CEH15960.1 - 7.2e-26 90.4 0.0 2.2e-25 88.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH15960.1 - 1.7e-15 57.3 0.0 3.1e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CEH15960.1 - 2.6e-13 49.4 0.1 4.2e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEH15960.1 - 2.5e-11 43.2 0.1 7.5e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEH15960.1 - 2.1e-08 33.8 0.0 5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase GST_N PF02798.15 CEH15961.1 - 3.7e-10 39.8 0.0 5.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CEH15961.1 - 3.9e-09 36.5 0.0 7.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEH15961.1 - 2e-08 34.0 0.0 3.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PTS_EIIC_2 PF13303.1 CEH15961.1 - 0.043 12.6 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC UCH PF00443.24 CEH15962.1 - 3.7e-64 216.4 0.0 5.1e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEH15962.1 - 4.4e-25 88.7 0.0 7.3e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 CEH15962.1 - 0.00019 21.3 0.5 0.00035 20.4 0.3 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain zf-MIZ PF02891.15 CEH15962.1 - 0.003 17.0 0.1 0.0078 15.7 0.1 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger ADIP PF11559.3 CEH15963.1 - 1.4e-13 50.9 10.2 1.4e-13 50.9 7.1 4.0 3 1 1 4 4 4 1 Afadin- and alpha -actinin-Binding CPSase_sm_chain PF00988.17 CEH15964.1 - 7.8e-45 151.5 0.0 1.3e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CEH15964.1 - 1.6e-35 122.2 0.0 2.4e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CEH15964.1 - 2.1e-05 24.0 0.1 0.00028 20.4 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 PTS_EIIA_1 PF00358.15 CEH15964.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RVT_1 PF00078.22 CEH15967.1 - 1.8e-15 56.8 0.0 3.7e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEH15967.1 - 9.7e-15 54.7 0.0 2.2e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CEH15967.1 - 1.5e-12 47.0 0.0 3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CEH15969.1 - 5.5e-19 68.4 0.0 1.4e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEH15969.1 - 8e-08 31.8 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CEH15969.1 - 0.0016 18.9 0.0 0.0037 17.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DDE_3 PF13358.1 CEH15969.1 - 0.07 12.8 0.1 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease Myc_target_1 PF15179.1 CEH15971.1 - 1.1 8.7 8.9 0.064 12.8 2.3 1.8 2 0 0 2 2 2 0 Myc target protein 1 MAP65_ASE1 PF03999.7 CEH15973.1 - 9 4.7 6.3 12 4.2 4.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PTPLA PF04387.9 CEH15975.1 - 8.2e-49 165.1 2.2 8.2e-49 165.1 1.5 1.6 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Glycos_transf_2 PF00535.21 CEH15976.1 - 3.2e-19 69.2 0.0 5.8e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CEH15976.1 - 6.2e-08 32.7 0.0 2e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CEH15976.1 - 0.038 14.2 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF3848 PF12959.2 CEH15976.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Vfa1 PF08432.5 CEH15977.1 - 0.24 11.4 6.5 0.5 10.3 4.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BAR PF03114.13 CEH15978.1 - 3.1e-48 164.3 2.4 3.6e-48 164.0 1.7 1.1 1 0 0 1 1 1 1 BAR domain AAA_13 PF13166.1 CEH15978.1 - 0.015 13.8 0.8 0.02 13.3 0.6 1.3 1 0 0 1 1 1 0 AAA domain Arfaptin PF06456.8 CEH15978.1 - 0.046 13.0 2.1 0.07 12.4 1.5 1.3 1 1 0 1 1 1 0 Arfaptin-like domain Tropomyosin PF00261.15 CEH15978.1 - 0.26 10.3 5.8 0.57 9.2 0.3 2.3 2 0 0 2 2 2 0 Tropomyosin Cpn60_TCP1 PF00118.19 CEH15981.1 - 5e-136 454.1 8.5 5.9e-136 453.9 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_pol3_beta PF00712.14 CEH15981.1 - 0.015 15.1 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain BCDHK_Adom3 PF10436.4 CEH15983.1 - 6.6e-61 204.6 0.0 9.4e-61 204.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CEH15983.1 - 9.8e-19 67.1 0.0 2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CEH15983.1 - 8.5e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA PF00004.24 CEH15984.1 - 4.4e-45 153.1 0.0 2.6e-44 150.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CEH15984.1 - 7.7e-09 35.3 0.1 2.6e-08 33.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CEH15984.1 - 7.3e-08 32.5 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CEH15984.1 - 9.6e-07 29.0 0.6 0.00033 20.7 0.3 2.9 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CEH15984.1 - 1.2e-06 28.6 0.1 5.2e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 CEH15984.1 - 2.7e-06 26.4 0.2 1.5e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CEH15984.1 - 0.00023 21.1 0.4 0.0008 19.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 CEH15984.1 - 0.00041 19.4 0.0 0.00088 18.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CEH15984.1 - 0.00049 19.7 0.1 0.0013 18.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CEH15984.1 - 0.00059 19.7 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CEH15984.1 - 0.00061 19.4 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CEH15984.1 - 0.00068 19.3 0.2 0.0028 17.3 0.0 2.2 3 0 0 3 3 2 1 NTPase NACHT PF05729.7 CEH15984.1 - 0.00091 18.9 0.1 0.034 13.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 CEH15984.1 - 0.0013 19.5 0.1 0.0047 17.7 0.0 1.9 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 CEH15984.1 - 0.0014 17.3 0.0 0.0027 16.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 CEH15984.1 - 0.0025 18.1 0.0 0.014 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CEH15984.1 - 0.003 17.6 0.0 0.0065 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 CEH15984.1 - 0.0034 17.2 0.0 0.0079 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CEH15984.1 - 0.0048 16.3 0.3 0.023 14.1 0.0 2.2 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_3 PF07726.6 CEH15984.1 - 0.0058 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CEH15984.1 - 0.0058 16.3 0.3 0.092 12.4 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase UPF0079 PF02367.12 CEH15984.1 - 0.006 16.2 0.0 0.02 14.5 0.0 1.8 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 CEH15984.1 - 0.0063 16.1 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CEH15984.1 - 0.0063 15.7 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CEH15984.1 - 0.0076 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 CEH15984.1 - 0.014 14.9 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CEH15984.1 - 0.015 15.6 0.7 0.42 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CEH15984.1 - 0.018 14.4 3.7 0.048 13.0 0.1 2.5 2 1 1 3 3 3 0 AAA domain Bac_DnaA PF00308.13 CEH15984.1 - 0.029 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AFG1_ATPase PF03969.11 CEH15984.1 - 0.055 12.2 0.0 0.14 10.9 0.0 1.7 1 0 0 1 1 1 0 AFG1-like ATPase Parvo_NS1 PF01057.12 CEH15984.1 - 0.057 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 CEH15984.1 - 0.09 12.2 0.2 1.4 8.3 0.0 2.5 3 1 0 3 3 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CEH15984.1 - 0.1 12.6 0.1 0.96 9.4 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 CEH15984.1 - 0.12 11.5 0.4 0.52 9.3 0.0 2.1 3 0 0 3 3 2 0 KaiC AAA_29 PF13555.1 CEH15984.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CEH15984.1 - 0.27 10.6 2.8 0.52 9.7 0.3 2.8 2 1 0 2 2 2 0 AAA-like domain Ctr PF04145.10 CEH15985.1 - 3.4e-26 92.0 2.1 4e-26 91.7 1.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 CEH15985.1 - 0.11 12.0 0.1 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Ferric_reduct PF01794.14 CEH15986.1 - 2.8e-20 72.6 13.2 2.8e-20 72.6 9.2 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CEH15986.1 - 1.8e-12 47.4 0.0 2.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CEH15986.1 - 5.7e-09 35.7 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 CEH15986.1 - 0.0014 19.1 0.0 0.0083 16.6 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain TP_methylase PF00590.15 CEH15986.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Cpn60_TCP1 PF00118.19 CEH15988.1 - 2e-146 488.4 2.1 2.3e-146 488.2 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family START PF01852.14 CEH15989.1 - 5.6e-11 42.1 0.1 1.9e-07 30.6 0.1 3.0 3 0 0 3 3 3 2 START domain PP2C_C PF07830.8 CEH15992.1 - 0.098 12.7 0.2 0.33 11.0 0.2 1.9 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain gag_pre-integrs PF13976.1 CEH15994.1 - 2.4e-05 23.8 0.2 4.9e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_2 PF07727.9 CEH15995.1 - 1.6e-69 233.6 0.0 2.1e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Proteasome PF00227.21 CEH15995.1 - 0.0059 15.8 0.1 0.021 14.0 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit DUF4310 PF14187.1 CEH15998.1 - 0.0065 15.9 0.8 0.01 15.3 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4310) ZZ PF00569.12 CEH15999.1 - 5.7e-09 35.3 32.4 2e-06 27.2 7.4 3.0 3 0 0 3 3 3 2 Zinc finger, ZZ type Gly-zipper_Omp PF13488.1 CEH16000.1 - 0.014 15.0 3.8 0.034 13.7 2.6 1.6 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.10 CEH16000.1 - 0.032 13.9 4.1 0.087 12.5 2.9 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF1183 PF06682.7 CEH16000.1 - 0.61 9.6 3.6 1 8.8 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF1049 PF06305.6 CEH16000.1 - 4 6.9 6.3 0.53 9.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) HSP70 PF00012.15 CEH16001.1 - 0.21 9.4 0.0 0.37 8.6 0.0 1.5 1 0 0 1 1 1 0 Hsp70 protein HSP70 PF00012.15 CEH16002.1 - 0.0045 14.9 0.0 0.02 12.8 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein Pol_alpha_B_N PF08418.5 CEH16002.1 - 0.1 12.0 1.5 0.33 10.4 1.0 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal OTU PF02338.14 CEH16004.1 - 4.6e-05 23.9 1.2 0.00012 22.6 0.1 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease DUF4246 PF14033.1 CEH16006.1 - 2.4e-112 376.1 0.0 3.9e-112 375.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) HLH PF00010.21 CEH16007.1 - 5.8e-06 25.9 0.0 1.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vasculin PF15337.1 CEH16007.1 - 0.052 14.0 2.2 0.086 13.3 0.0 2.4 2 1 0 2 2 2 0 Vascular protein family Vasculin-like 1 LETM1 PF07766.8 CEH16008.1 - 4.9e-98 327.4 2.3 4.9e-98 327.4 1.6 2.3 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 CEH16008.1 - 0.00021 21.3 0.4 0.0042 17.1 0.0 3.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 CEH16008.1 - 0.0029 17.3 0.1 3.8 7.6 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 CEH16008.1 - 0.0037 16.4 1.9 0.17 11.2 0.0 3.7 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 CEH16008.1 - 0.071 12.7 1.8 0.21 11.2 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair DUF3719 PF12516.3 CEH16008.1 - 0.08 12.5 2.8 0.11 12.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) Mob_synth_C PF06463.8 CEH16009.1 - 6.1e-32 110.0 0.0 3e-31 107.7 0.0 2.0 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C MoaC PF01967.16 CEH16010.1 - 1.5e-14 53.7 0.6 9.9e-08 31.7 0.1 2.1 2 0 0 2 2 2 2 MoaC family zf-C2H2 PF00096.21 CEH16011.1 - 0.1 12.9 3.9 0.22 11.9 2.7 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH16011.1 - 0.57 10.6 5.6 1.1 9.6 3.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger PBP-Tp47_c PF14888.1 CEH16012.1 - 0.053 13.1 0.9 0.18 11.3 0.0 1.9 1 1 1 2 2 2 0 Penicillin-binding protein Tp47 domain C ETRAMP PF09716.5 CEH16012.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PHD PF00628.24 CEH16013.1 - 0.041 13.5 0.1 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 PHD-finger Cpn60_TCP1 PF00118.19 CEH16014.1 - 6.6e-139 463.6 1.4 6.7e-112 374.5 0.3 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family DEAD PF00270.24 CEH16015.1 - 5.2e-45 152.9 0.0 1.2e-44 151.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH16015.1 - 4.3e-22 77.7 1.1 7.6e-22 76.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CEH16015.1 - 0.0029 16.4 0.0 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain PLDc_2 PF13091.1 CEH16016.1 - 2.1e-05 24.2 0.0 4.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.17 CEH16016.1 - 0.0015 18.2 0.3 0.067 13.0 0.0 2.4 2 0 0 2 2 2 1 Phospholipase D Active site motif PNP_UDP_1 PF01048.15 CEH16018.1 - 8.3e-20 70.7 0.2 1.1e-19 70.4 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily ThiF PF00899.16 CEH16020.1 - 4.3e-33 114.0 0.1 7e-33 113.3 0.1 1.3 1 0 0 1 1 1 1 ThiF family TRAPPC9-Trs120 PF08626.6 CEH16021.1 - 3.1e-17 61.3 0.0 6.5e-17 60.2 0.0 1.4 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Mo-co_dimer PF03404.11 CEH16021.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain TRAPPC9-Trs120 PF08626.6 CEH16022.1 - 1.1e-31 109.2 0.0 1.9e-31 108.3 0.0 1.3 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Exo_endo_phos PF03372.18 CEH16024.1 - 2.9e-22 79.8 0.0 5.5e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNARE PF05739.14 CEH16025.1 - 4.8e-06 26.1 0.9 4.8e-06 26.1 0.6 2.9 3 0 0 3 3 3 2 SNARE domain NTF2 PF02136.15 CEH16026.1 - 1.7e-35 121.9 0.3 1.9e-35 121.8 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 CEH16026.1 - 0.0034 17.5 0.0 0.0043 17.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 CEH16026.1 - 0.01 16.1 0.0 0.013 15.9 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain SRP-alpha_N PF04086.8 CEH16027.1 - 2.8e-43 148.2 0.1 4.5e-43 147.6 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 CEH16027.1 - 4.4e-42 143.7 0.6 1.2e-31 109.6 0.1 3.2 1 1 1 2 2 2 2 SRP54-type protein, GTPase domain SRP54_N PF02881.14 CEH16027.1 - 8.8e-07 28.9 0.0 2.5e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 CEH16027.1 - 3.1e-06 26.7 0.0 8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 CEH16027.1 - 0.00012 22.2 0.0 0.00043 20.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEH16027.1 - 0.0022 18.0 1.0 0.041 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 CEH16027.1 - 0.013 15.1 0.0 0.051 13.2 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CEH16027.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain ArsA_ATPase PF02374.10 CEH16027.1 - 0.051 12.6 0.1 2.2 7.2 0.1 2.2 1 1 0 1 1 1 0 Anion-transporting ATPase Response_reg PF00072.19 CEH16027.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Response regulator receiver domain DUF3533 PF12051.3 CEH16028.1 - 2.8e-79 266.6 16.9 3.3e-79 266.3 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) NIF PF03031.13 CEH16029.1 - 1.7e-40 138.3 0.0 3.1e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PRELI PF04707.9 CEH16030.1 - 1.9e-31 108.7 0.0 2.6e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Aminotran_4 PF01063.14 CEH16030.1 - 0.016 14.6 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class IV Ribosomal_L22 PF00237.14 CEH16031.1 - 2e-32 111.2 0.0 2.7e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Proteasome PF00227.21 CEH16033.1 - 4.8e-36 123.8 0.0 5.5e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L5_C PF00673.16 CEH16034.1 - 0.015 15.0 0.0 0.043 13.5 0.0 1.7 1 1 0 1 1 1 0 ribosomal L5P family C-terminus Herpes_capsid PF06112.6 CEH16034.1 - 3.6 7.6 13.2 8.8 6.3 9.2 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PGI PF00342.14 CEH16035.1 - 1.9e-205 682.9 0.0 2.2e-205 682.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase C2 PF00168.25 CEH16036.1 - 5.9e-18 64.5 0.0 5.4e-14 51.7 0.0 2.6 2 0 0 2 2 2 2 C2 domain DUF788 PF05620.6 CEH16037.1 - 3.4e-37 127.8 0.3 4.4e-37 127.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Med18 PF09637.5 CEH16038.1 - 0.066 12.7 0.0 4 6.8 0.0 2.3 2 0 0 2 2 2 0 Med18 protein Fork_head PF00250.13 CEH16039.1 - 8.3e-19 67.4 0.1 2.8e-18 65.7 0.1 1.8 1 1 0 1 1 1 1 Fork head domain THF_DHG_CYH PF00763.18 CEH16039.1 - 4.1e-13 49.3 0.0 8.6e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CEH16039.1 - 2e-11 43.2 0.0 7.1e-08 31.6 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TPR_11 PF13414.1 CEH16040.1 - 8e-22 76.6 10.5 3.3e-09 36.2 0.0 3.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 CEH16040.1 - 5.1e-15 54.3 8.4 0.00046 19.6 0.6 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEH16040.1 - 2.2e-13 49.0 11.4 4e-05 23.1 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEH16040.1 - 3.6e-13 49.7 9.3 3.3e-09 37.1 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEH16040.1 - 2.8e-12 46.3 4.8 6.9e-05 22.7 0.0 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CEH16040.1 - 6.5e-10 38.4 2.8 0.012 15.7 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CEH16040.1 - 1.2e-08 35.1 5.4 0.00052 20.2 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH16040.1 - 1.2e-08 34.8 9.8 0.017 15.7 0.3 4.2 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 CEH16040.1 - 7.9e-07 28.8 1.2 5.6e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEH16040.1 - 1.3e-06 28.4 2.8 0.024 15.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEH16040.1 - 8.8e-06 25.1 5.4 0.85 9.5 0.2 4.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CEH16040.1 - 0.0077 15.9 4.9 0.97 9.3 0.0 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CEH16040.1 - 0.022 14.9 3.1 0.15 12.2 0.3 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 YfiO PF13525.1 CEH16040.1 - 0.042 13.3 0.1 0.089 12.2 0.1 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein TPR_10 PF13374.1 CEH16040.1 - 0.058 13.3 3.7 5.6 7.0 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Ring_hydroxyl_A PF00848.14 CEH16040.1 - 0.14 11.7 0.0 0.37 10.4 0.0 1.6 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) SPC25 PF06703.6 CEH16041.1 - 1e-32 112.9 0.0 1.4e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) AF1Q PF15017.1 CEH16041.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator PSP PF04046.11 CEH16042.1 - 0.012 14.9 0.0 0.036 13.4 0.0 1.8 1 0 0 1 1 1 0 PSP Lactamase_B_3 PF13483.1 CEH16042.1 - 0.096 12.3 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain TRAP_alpha PF03896.11 CEH16043.1 - 5.8e-05 22.2 0.0 0.00014 20.9 0.0 1.6 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit UvdE PF03851.9 CEH16044.1 - 2.1e-81 273.0 0.0 2.9e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE His_Phos_2 PF00328.17 CEH16045.1 - 1.9e-09 37.2 0.0 2.5e-08 33.6 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sulfate_transp PF00916.15 CEH16046.1 - 5.3e-78 261.8 10.3 8.2e-78 261.2 7.1 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CEH16046.1 - 2.9e-30 103.7 4.1 2.9e-30 103.7 2.8 3.7 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CEH16046.1 - 4.9e-07 29.1 0.0 9.8e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF2034 PF10356.4 CEH16047.1 - 5.5e-20 71.3 0.0 5.7e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 CEH16047.1 - 0.016 14.9 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease MFS_1 PF07690.11 CEH16049.1 - 2e-37 128.7 40.9 2e-37 128.7 28.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH16049.1 - 3.2e-14 52.3 4.8 3.2e-14 52.3 3.4 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 CEH16049.1 - 7.5e-13 47.5 17.0 1.1e-12 47.0 11.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3899 PF13038.1 CEH16049.1 - 0.19 11.8 1.7 0.85 9.8 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Abhydrolase_6 PF12697.2 CEH16050.1 - 1.3e-18 67.7 0.3 2.2e-18 66.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH16050.1 - 2e-11 43.8 0.1 3.9e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CEH16050.1 - 6.9e-05 22.2 0.5 0.064 12.5 0.0 2.8 3 0 0 3 3 3 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CEH16050.1 - 0.00022 21.0 1.2 0.00041 20.1 0.9 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CEH16050.1 - 0.00073 19.1 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 CEH16050.1 - 0.0075 15.8 0.0 0.26 10.8 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 CEH16050.1 - 0.041 13.2 0.1 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Putative esterase RasGEF PF00617.14 CEH16051.1 - 2.4e-61 206.7 0.1 4e-61 206.0 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEH16051.1 - 2.6e-28 98.1 0.2 6.4e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 CEH16051.1 - 1e-11 43.9 0.1 2.2e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEH16051.1 - 3.6e-10 39.2 0.1 7.9e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEH16051.1 - 1.7e-09 36.9 0.0 4.2e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 CEH16051.1 - 0.042 13.7 0.0 0.57 10.1 0.0 2.4 2 0 0 2 2 2 0 WW domain Isy1 PF06246.7 CEH16053.1 - 2.8e-75 253.0 0.4 8.3e-75 251.4 0.3 1.7 1 1 0 1 1 1 1 Isy1-like splicing family SPT2 PF08243.6 CEH16053.1 - 2.8 8.2 6.0 1.1 9.5 1.5 2.2 3 0 0 3 3 3 0 SPT2 chromatin protein Bot1p PF12298.3 CEH16054.1 - 3.3e-23 82.4 0.9 3.5e-22 79.1 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein zf-RING_2 PF13639.1 CEH16057.1 - 2.9e-12 46.1 13.3 2.4e-08 33.6 3.1 3.5 3 0 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.2 CEH16057.1 - 2.2e-06 27.6 9.7 1.2e-05 25.3 0.8 2.9 3 0 0 3 3 3 2 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CEH16057.1 - 0.00025 20.6 1.8 0.00025 20.6 1.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH16057.1 - 0.0034 17.3 13.7 0.0048 16.8 2.7 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH16057.1 - 0.0035 16.9 13.5 0.015 14.9 1.9 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 CEH16057.1 - 0.0039 17.1 2.4 0.0039 17.1 1.7 2.3 2 1 0 2 2 2 1 RING-variant domain zf-Apc11 PF12861.2 CEH16057.1 - 0.0061 16.3 0.9 0.0061 16.3 0.6 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CEH16057.1 - 0.0069 16.0 13.6 0.012 15.2 1.6 3.3 3 0 0 3 3 3 1 zinc-RING finger domain UreE_N PF02814.10 CEH16057.1 - 0.11 11.9 0.6 1 8.8 0.0 2.6 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain PHD PF00628.24 CEH16057.1 - 2.7 7.7 17.7 0.42 10.3 1.9 4.2 5 0 0 5 5 5 0 PHD-finger Med3 PF11593.3 CEH16057.1 - 7.1 5.7 12.9 5.7 6.0 3.6 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal ThiF PF00899.16 CEH16058.1 - 1.3e-35 122.1 0.0 3e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CEH16058.1 - 4.5e-27 93.4 0.0 8.1e-27 92.6 0.0 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CEH16058.1 - 4.5e-21 73.9 2.3 7.7e-21 73.2 1.6 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 CEH16058.1 - 1.3e-07 31.5 0.4 3.7e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 CEH16058.1 - 0.0042 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CEH16058.1 - 0.031 14.5 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Dermcidin PF15291.1 CEH16058.1 - 0.14 12.3 0.2 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide Abhydrolase_1 PF00561.15 CEH16059.1 - 1.3e-23 83.7 0.2 8.1e-18 64.8 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEH16059.1 - 3.5e-13 49.9 5.5 7.1e-12 45.6 3.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CEH16059.1 - 4e-05 23.1 0.2 6.6e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CEH16059.1 - 0.00012 21.8 0.1 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family COesterase PF00135.23 CEH16062.1 - 4.4e-84 283.1 0.0 7.3e-84 282.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CEH16062.1 - 6.4e-10 38.9 1.7 4.9e-09 36.0 1.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold A2M_N PF01835.14 CEH16063.1 - 0.063 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 MG2 domain F-box-like PF12937.2 CEH16064.1 - 0.00015 21.4 0.4 0.00028 20.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH16064.1 - 0.00073 19.1 0.5 0.0014 18.1 0.4 1.4 1 0 0 1 1 1 1 F-box domain ECH PF00378.15 CEH16065.1 - 5.9e-32 110.7 0.0 1.6e-31 109.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family GATase_2 PF00310.16 CEH16066.1 - 2.3e-25 89.0 0.1 9.1e-20 70.6 0.0 2.5 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Pribosyltran PF00156.22 CEH16066.1 - 7.2e-15 54.8 0.3 1.3e-14 54.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_6 PF13522.1 CEH16066.1 - 6.1e-14 52.1 0.3 1.7e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CEH16066.1 - 4.3e-11 42.6 0.0 8.3e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CEH16066.1 - 3.7e-07 29.1 0.0 6.2e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glyco_transf_90 PF05686.7 CEH16068.1 - 4.1e-22 78.4 7.2 5.5e-18 64.8 3.2 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF3317 PF11779.3 CEH16068.1 - 3.9 6.9 5.8 25 4.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3317) PTR2 PF00854.16 CEH16071.1 - 5.8e-45 153.6 8.2 4.3e-44 150.8 5.7 2.0 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 CEH16071.1 - 2.8e-12 46.0 16.0 6.4e-12 44.8 8.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily SAE2 PF08573.5 CEH16072.1 - 9e-10 39.1 2.7 9e-10 39.1 1.9 5.0 4 2 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SlyX PF04102.7 CEH16072.1 - 0.063 13.6 0.7 0.063 13.6 0.5 3.4 3 0 0 3 3 3 0 SlyX HALZ PF02183.13 CEH16072.1 - 0.59 9.8 5.7 0.71 9.6 0.1 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper IncA PF04156.9 CEH16072.1 - 3.4 7.2 12.9 0.52 9.8 1.8 3.0 3 0 0 3 3 3 0 IncA protein Abhydrolase_5 PF12695.2 CEH16073.1 - 0.027 14.2 0.4 0.053 13.2 0.2 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3899 PF13038.1 CEH16073.1 - 1.9 8.7 3.9 22 5.2 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) UBX PF00789.15 CEH16074.1 - 7.4e-10 38.7 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Glyco_hydro_18 PF00704.23 CEH16076.1 - 2.2e-81 274.0 0.0 2.5e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HIG_1_N PF04588.8 CEH16077.1 - 2.3e-18 65.6 0.3 3.1e-18 65.2 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Milton PF12448.3 CEH16077.1 - 0.023 14.8 0.9 0.034 14.3 0.7 1.2 1 0 0 1 1 1 0 Kinesin associated protein Zn_clus PF00172.13 CEH16078.1 - 5.7e-07 29.3 7.6 1.2e-06 28.2 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CEH16078.1 - 7e-05 21.8 0.0 0.00018 20.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S9 PF00326.16 CEH16079.1 - 7.1e-09 35.1 1.0 4.7e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CEH16079.1 - 1.2e-06 28.2 0.1 0.0074 15.8 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH16079.1 - 0.00031 20.5 0.0 0.00056 19.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 CEH16079.1 - 0.0046 16.2 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_2 PF02230.11 CEH16079.1 - 0.0074 15.7 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase UPF0227 PF05728.7 CEH16079.1 - 0.057 13.1 0.0 9.5 5.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) ASL_C2 PF14698.1 CEH16081.1 - 1.3e-27 95.5 0.1 2.1e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Lyase_1 PF00206.15 CEH16081.1 - 1.8e-10 40.5 0.0 3.5e-10 39.5 0.0 1.4 2 0 0 2 2 2 1 Lyase Lyase_1 PF00206.15 CEH16082.1 - 7.7e-80 268.3 0.0 8.6e-80 268.2 0.0 1.0 1 0 0 1 1 1 1 Lyase Hormone_1 PF00103.15 CEH16083.1 - 0.0059 15.9 1.3 0.14 11.4 0.4 2.9 2 1 1 3 3 3 1 Somatotropin hormone family Reo_sigmaC PF04582.7 CEH16083.1 - 0.12 11.5 8.5 3.5 6.7 0.0 2.7 3 0 0 3 3 3 0 Reovirus sigma C capsid protein HALZ PF02183.13 CEH16083.1 - 0.22 11.2 14.5 4.3 7.1 0.4 4.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF904 PF06005.7 CEH16083.1 - 9.8 6.5 26.3 9.9 6.5 0.8 5.9 3 1 2 5 5 5 0 Protein of unknown function (DUF904) DUF1664 PF07889.7 CEH16083.1 - 9.9 5.9 13.8 0.65 9.8 0.5 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Sterol-sensing PF12349.3 CEH16084.1 - 4.2e-42 143.2 14.7 7.3e-42 142.4 10.2 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CEH16084.1 - 2.1e-16 59.0 7.0 3e-16 58.5 4.9 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 CEH16084.1 - 0.086 12.7 3.2 1 9.3 0.3 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Cation_efflux PF01545.16 CEH16085.1 - 8.8e-34 116.8 16.8 4.1e-31 108.1 7.4 3.6 2 1 0 3 3 3 3 Cation efflux family CLPTM1 PF05602.7 CEH16086.1 - 1.4e-83 281.1 0.0 2e-82 277.2 0.0 2.2 2 1 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 CEH16086.1 - 0.00059 19.3 1.5 0.00059 19.3 1.0 1.9 2 0 0 2 2 2 1 PQ loop repeat GPI-anchored PF10342.4 CEH16088.1 - 2.5e-05 24.6 0.0 4.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CEH16088.1 - 0.021 14.3 0.0 0.036 13.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) V-SNARE_C PF12352.3 CEH16089.1 - 9.9e-18 63.9 5.6 2.2e-17 62.8 3.9 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus IncA PF04156.9 CEH16089.1 - 0.037 13.6 1.4 0.073 12.6 1.0 1.5 1 0 0 1 1 1 0 IncA protein Sec20 PF03908.8 CEH16089.1 - 0.04 13.6 0.7 0.17 11.6 0.0 2.3 3 0 0 3 3 3 0 Sec20 DNA_pol_A_exo1 PF01612.15 CEH16090.1 - 6.3e-35 120.2 0.1 1.1e-34 119.4 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 CEH16090.1 - 6.1e-10 38.6 0.1 1.7e-09 37.2 0.1 1.8 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.7 CEH16090.1 - 3.7e-09 36.7 0.0 9e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 PMC2NT (NUC016) domain BLVR PF06375.6 CEH16090.1 - 0.074 12.8 2.0 0.18 11.6 1.4 1.6 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) BLOC1_2 PF10046.4 CEH16092.1 - 0.015 15.4 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SQS_PSY PF00494.14 CEH16092.1 - 0.016 14.4 0.1 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Squalene/phytoene synthase CK2S PF15011.1 CEH16092.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Casein Kinase 2 substrate HEM4 PF02602.10 CEH16092.1 - 0.08 12.1 0.0 0.096 11.9 0.0 1.2 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD PMAIP1 PF15150.1 CEH16093.1 - 0.037 13.8 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced DUF3818 PF12825.2 CEH16094.1 - 6.7e-46 156.5 0.0 9e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CEH16094.1 - 0.049 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 PX-associated Peptidase_M74 PF03411.8 CEH16094.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase Epimerase PF01370.16 CEH16095.1 - 3.4e-19 69.2 0.0 6.5e-19 68.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEH16095.1 - 5.2e-13 49.4 0.2 3.9e-12 46.5 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CEH16095.1 - 1.2e-11 43.8 0.0 1.8e-11 43.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CEH16095.1 - 1.6e-11 43.5 0.0 2.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 CEH16095.1 - 1.5e-09 37.5 0.1 2.1e-08 33.6 0.3 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 CEH16095.1 - 7.5e-07 28.3 0.0 1.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CEH16095.1 - 0.00098 19.0 0.2 0.0021 17.9 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH16095.1 - 0.065 12.9 1.9 0.86 9.2 1.3 2.3 1 1 0 1 1 1 0 KR domain Clat_adaptor_s PF01217.15 CEH16096.1 - 3.2e-17 62.5 0.1 4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA PF00004.24 CEH16097.1 - 2.2e-12 47.2 0.0 5.5e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CEH16097.1 - 1.4e-07 30.6 0.2 0.0016 17.2 0.0 3.1 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CEH16097.1 - 6.7e-06 25.3 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CEH16097.1 - 1.2e-05 24.9 0.3 0.0001 21.9 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 CEH16097.1 - 6.1e-05 23.0 1.3 0.0093 15.9 0.0 3.7 3 1 1 4 4 3 1 AAA ATPase domain AAA_14 PF13173.1 CEH16097.1 - 0.00015 21.6 0.0 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEH16097.1 - 0.00081 19.5 0.0 0.0046 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CEH16097.1 - 0.0018 17.9 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CEH16097.1 - 0.0031 18.3 0.6 0.012 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CEH16097.1 - 0.0046 16.8 0.0 0.016 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CEH16097.1 - 0.041 13.5 0.0 0.1 12.3 0.0 1.6 1 1 0 1 1 1 0 NTPase T2SE PF00437.15 CEH16097.1 - 0.045 12.6 0.0 0.089 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 CEH16097.1 - 0.09 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEH16097.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 CEH16097.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 CEH16097.1 - 0.18 10.9 0.0 0.4 9.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CEH16097.1 - 0.28 10.8 0.0 1.2 8.7 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase Chitin_synth_2 PF03142.10 CEH16098.1 - 1.6e-283 940.9 0.0 2e-283 940.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CEH16098.1 - 1.4e-17 64.0 1.2 3.7e-17 62.6 0.8 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEH16098.1 - 2e-16 60.5 0.0 5.1e-16 59.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CEH16098.1 - 4.7e-06 26.0 0.0 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CEH16098.1 - 0.013 15.1 0.0 0.043 13.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 TraL PF07178.6 CEH16098.1 - 0.059 13.3 0.4 0.21 11.6 0.3 1.9 1 0 0 1 1 1 0 TraL protein Fungal_trans PF04082.13 CEH16099.1 - 8.8e-12 44.4 0.0 6.8e-11 41.5 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 CEH16099.1 - 7.5e-07 29.1 9.0 0.00049 20.2 1.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH16099.1 - 0.00023 21.2 6.0 0.03 14.6 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEH16099.1 - 0.014 15.6 0.5 0.014 15.6 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 CEH16099.1 - 0.03 14.2 0.9 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger YchF-GTPase_C PF06071.8 CEH16100.1 - 1.5e-34 117.5 0.2 3.3e-34 116.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CEH16100.1 - 1.9e-13 50.3 0.0 9.4e-13 48.1 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEH16100.1 - 4.1e-05 22.9 0.0 7.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GATA PF00320.22 CEH16101.1 - 1.1e-13 50.2 3.5 2.2e-13 49.3 2.4 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CEH16101.1 - 0.22 10.8 0.3 0.38 10.1 0.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Haemolytic PF01809.13 CEH16102.1 - 0.052 13.1 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Haemolytic domain PLU-1 PF08429.6 CEH16103.1 - 2.2e-46 158.3 0.5 3.7e-46 157.5 0.3 1.3 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.17 CEH16103.1 - 5.4e-41 139.4 0.2 1.3e-40 138.1 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 CEH16103.1 - 1.2e-25 88.9 52.3 9.6e-13 47.6 2.6 3.9 4 0 0 4 4 4 3 PHD-finger ARID PF01388.16 CEH16103.1 - 5.8e-20 70.9 0.0 1.3e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 CEH16103.1 - 7.3e-15 54.1 0.1 1.6e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 CEH16103.1 - 2.3e-10 40.3 3.4 7.4e-10 38.7 2.3 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger Prok-RING_1 PF14446.1 CEH16103.1 - 0.001 18.7 28.4 0.046 13.4 4.5 3.8 3 0 0 3 3 3 3 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CEH16103.1 - 0.87 8.9 28.7 2.6 7.4 0.6 3.6 3 0 0 3 3 3 0 PHD-finger Vps54 PF07928.7 CEH16104.1 - 7.8e-54 181.4 1.4 1.4e-53 180.6 1.0 1.4 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.4 CEH16104.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF2450 PF10475.4 CEH16104.1 - 0.074 11.9 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) RINT1_TIP1 PF04437.8 CEH16104.1 - 0.16 10.5 0.1 0.31 9.5 0.1 1.4 1 0 0 1 1 1 0 RINT-1 / TIP-1 family zf-MYND PF01753.13 CEH16105.1 - 7.9e-08 32.0 14.1 1.6e-07 31.0 9.8 1.5 1 0 0 1 1 1 1 MYND finger TIP49 PF06068.8 CEH16106.1 - 5.2e-177 588.4 0.5 6.2e-177 588.2 0.4 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CEH16106.1 - 4.8e-10 39.7 1.8 1.1e-07 32.1 0.0 3.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CEH16106.1 - 9.9e-08 31.3 3.2 0.0001 21.4 0.0 3.3 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CEH16106.1 - 1.3e-07 31.7 0.1 4.2e-07 30.1 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 CEH16106.1 - 7.1e-07 29.4 0.3 0.006 16.7 0.1 2.7 1 1 1 2 2 2 2 AAA domain DnaB_C PF03796.10 CEH16106.1 - 9.2e-06 24.7 0.1 2.1e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.9 CEH16106.1 - 2e-05 24.3 0.1 0.0091 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CEH16106.1 - 0.00017 21.0 0.7 0.00047 19.6 0.1 2.0 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CEH16106.1 - 0.00027 20.1 0.4 0.011 14.9 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CEH16106.1 - 0.00041 20.2 0.0 1 9.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CEH16106.1 - 0.00087 18.9 0.1 0.00087 18.9 0.0 2.4 3 0 0 3 3 1 1 Part of AAA domain AAA_17 PF13207.1 CEH16106.1 - 0.0011 19.7 0.2 0.0033 18.2 0.0 2.1 2 1 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 CEH16106.1 - 0.0028 17.1 0.0 1.4 8.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 CEH16106.1 - 0.0034 16.5 0.0 0.0084 15.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CEH16106.1 - 0.017 15.4 1.3 0.088 13.1 0.9 2.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CEH16106.1 - 0.019 14.3 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 CEH16106.1 - 0.025 13.5 0.1 0.053 12.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 CEH16106.1 - 0.025 14.2 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 CEH16106.1 - 0.025 14.4 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CEH16106.1 - 0.027 14.2 3.0 0.5 10.0 0.6 3.2 2 1 0 2 2 2 0 NTPase AAA_11 PF13086.1 CEH16106.1 - 0.03 13.9 0.1 0.048 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CEH16106.1 - 0.036 14.0 0.1 0.13 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.15 CEH16106.1 - 0.12 10.9 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Pil1 PF13805.1 CEH16107.1 - 5.9e-24 84.6 0.0 5.9e-24 84.6 0.0 1.8 2 0 0 2 2 2 1 Eisosome component PIL1 DUF3808 PF10300.4 CEH16108.1 - 1.9e-73 247.6 0.5 3.5e-73 246.7 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.15 CEH16108.1 - 3.9e-31 107.7 0.0 8.7e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CEH16108.1 - 9.8e-14 51.5 0.0 2.7e-12 46.8 0.0 2.4 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEH16108.1 - 3.6e-10 39.8 2.7 7.5e-10 38.7 0.3 2.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain TPR_11 PF13414.1 CEH16108.1 - 1.4e-05 24.6 5.2 0.63 9.7 0.0 5.1 3 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.1 CEH16108.1 - 0.00085 19.2 7.6 0.7 9.8 0.3 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 CEH16108.1 - 0.011 15.6 12.1 2.3 8.3 0.6 5.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEH16108.1 - 0.029 14.1 6.4 1.7 8.5 0.3 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Gly-zipper_YMGG PF13441.1 CEH16108.1 - 0.17 11.4 24.0 0.21 11.1 5.9 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper TPR_1 PF00515.23 CEH16108.1 - 0.29 10.7 7.7 1.5 8.5 0.5 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEH16108.1 - 0.4 11.2 6.0 11 6.6 0.2 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEH16108.1 - 1.4 8.8 5.1 8 6.5 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_60s PF00428.14 CEH16108.1 - 2.4 8.6 47.2 0.37 11.2 8.9 3.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Bacteriocin_IIc PF10439.4 CEH16108.1 - 8.6 6.5 11.0 4 7.6 2.1 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Ribosomal_L12 PF00542.14 CEH16109.1 - 2.3e-18 65.9 8.9 5.4e-18 64.7 4.5 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain RhoGAP PF00620.22 CEH16110.1 - 0.028 14.0 0.0 0.14 11.8 0.0 2.1 2 1 0 2 2 2 0 RhoGAP domain Polysacc_deac_1 PF01522.16 CEH16111.1 - 1e-21 76.8 0.0 2.6e-21 75.5 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase OSTbeta PF15048.1 CEH16113.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Pyr_redox PF00070.22 CEH16114.1 - 8.9e-10 38.8 0.0 2.2e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEH16114.1 - 1.1e-09 38.4 2.2 1.3e-06 28.4 1.5 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CEH16114.1 - 0.00079 18.4 0.1 0.0025 16.8 0.0 1.7 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 CEH16114.1 - 0.0054 16.8 0.1 0.14 12.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEH16114.1 - 0.016 14.1 0.4 0.66 8.8 0.0 2.6 2 1 1 3 3 3 0 Lycopene cyclase protein DAO PF01266.19 CEH16114.1 - 0.055 12.3 5.6 0.49 9.2 0.0 2.9 2 1 0 3 3 3 0 FAD dependent oxidoreductase Lipase_GDSL_2 PF13472.1 CEH16114.1 - 0.12 12.5 0.0 0.65 10.0 0.0 1.9 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family RQC PF09382.5 CEH16115.1 - 4.4e-23 81.0 0.2 1e-22 79.8 0.2 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 CEH16115.1 - 2.4e-21 75.9 0.0 3.6e-20 72.1 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH16115.1 - 1.7e-18 66.2 0.1 4.7e-18 64.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HRDC PF00570.18 CEH16115.1 - 7.3e-07 28.8 0.2 2.4e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 HRDC domain Pro-kuma_activ PF09286.6 CEH16116.1 - 1e-15 57.9 0.1 2.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Zn_clus PF00172.13 CEH16117.1 - 1.6e-06 27.9 10.8 2.9e-06 27.1 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CEH16117.1 - 0.0015 17.4 0.0 0.0038 16.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDC73 PF05179.9 CEH16117.1 - 0.098 11.9 0.3 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 RNA pol II accessory factor, Cdc73 family K_oxygenase PF13434.1 CEH16118.1 - 1.6e-09 37.1 0.0 0.00098 18.1 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 CEH16118.1 - 1.8e-09 37.9 0.0 0.00015 21.8 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEH16118.1 - 0.0068 16.1 0.3 0.55 9.9 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 CEH16118.1 - 0.015 14.2 0.4 4.9 5.9 0.1 3.7 4 0 0 4 4 4 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 CEH16118.1 - 0.03 14.4 0.0 9.9 6.2 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 CEH16118.1 - 0.077 13.0 0.2 14 5.8 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Cob_adeno_trans PF01923.13 CEH16119.1 - 0.017 14.9 0.1 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Herpes_BLRF2 PF05812.7 CEH16119.1 - 0.023 14.5 0.9 0.089 12.6 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein SNAPc19 PF15497.1 CEH16119.1 - 0.03 14.5 0.2 0.069 13.3 0.1 1.6 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 MIP PF00230.15 CEH16121.1 - 9.3e-46 156.1 7.3 1.4e-45 155.5 5.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein Exo_endo_phos PF03372.18 CEH16121.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M76 PF09768.4 CEH16122.1 - 3.5e-60 202.4 1.9 5.1e-60 201.8 1.3 1.2 1 0 0 1 1 1 1 Peptidase M76 family Proteasome PF00227.21 CEH16123.1 - 3.4e-46 156.9 0.0 4.2e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEH16123.1 - 9.8e-14 50.3 0.6 6.7e-13 47.6 0.1 2.3 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-Mss51 PF13824.1 CEH16124.1 - 1.6e-15 56.6 0.0 3.1e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Urease_alpha PF00449.15 CEH16125.1 - 3.7e-55 185.2 1.1 7.4e-55 184.2 0.7 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_1 PF01979.15 CEH16125.1 - 3.3e-53 181.4 0.5 5.1e-53 180.8 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_gamma PF00547.13 CEH16125.1 - 2.2e-39 133.4 1.7 2.7e-39 133.1 0.1 2.0 3 0 0 3 3 3 1 Urease, gamma subunit Urease_beta PF00699.15 CEH16125.1 - 3.1e-34 116.7 0.0 6.7e-34 115.7 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_5 PF13594.1 CEH16125.1 - 2.7e-06 27.0 1.6 2.7e-06 27.0 1.1 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 CEH16125.1 - 0.00073 18.8 0.5 0.0034 16.6 0.1 2.2 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 CEH16125.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase PHD PF00628.24 CEH16127.1 - 4.4e-09 35.8 11.5 7.8e-09 35.0 8.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CEH16127.1 - 0.009 15.3 7.7 0.016 14.4 5.4 1.4 1 0 0 1 1 1 1 PHD-finger Prefoldin PF02996.12 CEH16128.1 - 1.5e-27 95.5 1.3 1.7e-27 95.4 0.6 1.3 1 1 0 1 1 1 1 Prefoldin subunit OmpH PF03938.9 CEH16128.1 - 0.22 11.4 6.7 0.028 14.3 1.0 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMF_TATA_bd PF12325.3 CEH16128.1 - 0.68 9.6 8.4 6 6.6 3.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.5 CEH16128.1 - 0.87 9.7 5.3 0.45 10.6 1.6 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 CEH16128.1 - 1.2 8.8 12.3 0.14 11.8 0.9 2.7 2 1 1 3 3 3 0 Prefoldin subunit IncA PF04156.9 CEH16128.1 - 4.5 6.8 8.8 6.5 6.2 0.2 2.1 2 0 0 2 2 2 0 IncA protein WD40 PF00400.27 CEH16129.1 - 2.4e-62 204.7 16.9 1.2e-07 31.3 0.0 11.7 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 CEH16129.1 - 1.2e-16 60.6 0.5 1.9e-16 59.9 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CEH16129.1 - 4e-06 25.2 0.4 0.38 8.8 0.0 4.6 2 2 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CEH16129.1 - 0.00092 18.0 0.0 13 4.4 0.0 5.0 2 2 3 5 5 5 1 Nup133 N terminal like RAB3GAP2_N PF14655.1 CEH16129.1 - 0.051 12.5 0.0 0.43 9.5 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hira PF07569.6 CEH16129.1 - 0.22 10.6 0.0 1.3 8.1 0.0 2.2 3 0 0 3 3 3 0 TUP1-like enhancer of split ECH PF00378.15 CEH16130.1 - 1.1e-15 57.5 0.0 2.4e-15 56.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family FlaF PF07309.6 CEH16130.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Flagellar protein FlaF Syja_N PF02383.13 CEH16131.1 - 4.9e-75 252.2 0.0 6.9e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CEH16131.1 - 1.4e-30 107.0 0.0 2.8e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF92 PF01940.11 CEH16133.1 - 5.8e-58 195.7 7.2 4.5e-56 189.5 5.0 2.2 1 1 0 1 1 1 1 Integral membrane protein DUF92 FMO-like PF00743.14 CEH16133.1 - 0.18 9.9 0.0 0.26 9.4 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like PMT_2 PF13231.1 CEH16133.1 - 0.41 10.5 4.4 0.33 10.8 1.1 2.2 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase EF-hand_4 PF12763.2 CEH16134.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand WD40 PF00400.27 CEH16135.1 - 1.8e-14 52.9 1.0 0.00023 20.9 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CEH16135.1 - 0.033 13.8 0.1 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term PQQ_3 PF13570.1 CEH16135.1 - 0.13 12.5 1.2 1.3 9.4 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain Nucleoporin_C PF03177.9 CEH16136.1 - 2.5e-79 267.3 4.1 3.3e-79 266.9 2.9 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CEH16136.1 - 1e-55 189.2 0.0 2e-55 188.2 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Cnd2 PF05786.9 CEH16137.1 - 6.5e-89 299.3 1.1 2.2e-80 271.1 0.1 2.1 2 0 0 2 2 2 2 Condensin complex subunit 2 TauD PF02668.11 CEH16138.1 - 5.8e-49 167.0 0.2 8.1e-49 166.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UnbV_ASPIC PF07593.7 CEH16138.1 - 0.0092 15.6 0.4 0.67 9.6 0.0 2.5 2 0 0 2 2 2 2 ASPIC and UnbV NUFIP1 PF10453.4 CEH16139.1 - 0.1 12.1 0.9 0.21 11.1 0.6 1.6 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) OTU PF02338.14 CEH16140.1 - 5.7e-07 30.1 0.0 9.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 CEH16140.1 - 0.027 14.7 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 TFIID_30kDa PF03540.8 CEH16141.1 - 4.2e-27 93.7 0.0 8e-27 92.8 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.23 CEH16141.1 - 7.8e-09 35.1 0.0 0.00087 19.0 0.0 2.4 2 0 0 2 2 2 2 CBS domain Glutaredoxin PF00462.19 CEH16143.1 - 8.1e-17 60.9 0.1 1.2e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Turandot PF07240.6 CEH16143.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot PLDc_2 PF13091.1 CEH16144.1 - 1.7e-15 56.8 0.0 2.8e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain HTH_28 PF13518.1 CEH16146.1 - 0.017 15.1 0.4 1.1 9.3 0.0 3.3 2 0 0 2 2 2 0 Helix-turn-helix domain RNase_HII PF01351.13 CEH16147.1 - 5.5e-41 140.3 0.0 2.5e-34 118.6 0.0 2.2 1 1 1 2 2 2 2 Ribonuclease HII FAM220 PF15487.1 CEH16149.1 - 0.16 11.2 3.6 0.3 10.4 2.5 1.4 1 0 0 1 1 1 0 FAM220 family DUF761 PF05553.6 CEH16149.1 - 0.18 11.1 0.5 5 6.5 0.0 2.4 2 0 0 2 2 2 0 Cotton fibre expressed protein GKAP PF03359.8 CEH16149.1 - 0.24 10.9 8.7 0.074 12.6 4.0 1.5 1 1 1 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein WD40 PF00400.27 CEH16150.1 - 3.1e-21 74.4 4.3 9.1e-09 34.8 0.0 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat Ribosomal_L28e PF01778.12 CEH16151.1 - 3e-27 95.3 1.6 7.9e-27 93.9 0.2 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 CEH16151.1 - 3.9e-19 68.6 22.2 3.9e-19 68.6 15.4 3.3 1 1 2 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.5 CEH16151.1 - 5.9e-05 22.3 24.1 7.8e-05 21.9 16.7 1.1 1 0 0 1 1 1 1 BUD22 Nup188 PF10487.4 CEH16152.1 - 6.6e-08 30.9 0.0 5.8e-07 27.8 0.0 2.4 3 0 0 3 3 3 1 Nucleoporin subcomplex protein binding to Pom34 Sybindin PF04099.7 CEH16153.1 - 3.6e-34 117.5 0.0 4e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CEH16153.1 - 5.4e-08 32.7 0.0 8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF1768 PF08719.6 CEH16154.1 - 1.4e-32 112.5 0.0 2e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.6 CEH16154.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Bacteriophage protein GP30.3 DUF3246 PF11596.3 CEH16155.1 - 0.006 15.8 15.1 0.0079 15.5 10.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Nfu_N PF08712.6 CEH16156.1 - 9.3e-34 114.9 0.1 1.7e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CEH16156.1 - 1.8e-22 78.8 0.1 3.1e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Abhydrolase_6 PF12697.2 CEH16158.1 - 2.1e-06 27.8 2.5 5.6e-06 26.3 1.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH16158.1 - 5.5e-06 26.1 0.1 1.1e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEH16158.1 - 0.0001 21.5 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.5 CEH16158.1 - 0.0025 16.7 0.0 0.0043 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF915 PF06028.6 CEH16158.1 - 0.0036 16.4 0.0 0.021 13.9 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) cwf21 PF08312.7 CEH16159.1 - 6e-14 51.6 9.6 6e-14 51.6 6.7 2.6 2 0 0 2 2 2 1 cwf21 domain CYSTM PF12734.2 CEH16160.1 - 0.02 14.9 33.7 0.02 14.9 23.4 5.4 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance MFS_1 PF07690.11 CEH16162.1 - 6.2e-51 173.1 45.6 6.7e-49 166.4 32.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CEH16162.1 - 1.3e-18 66.5 17.6 1.8e-18 66.1 12.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CEH16162.1 - 6.3e-17 61.2 3.9 6.3e-17 61.2 2.7 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter PUCC PF03209.10 CEH16162.1 - 0.0089 14.7 23.1 0.13 10.9 3.1 2.4 2 0 0 2 2 2 2 PUCC protein DUF2530 PF10745.4 CEH16162.1 - 0.047 13.6 2.9 0.11 12.4 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) ThiF PF00899.16 CEH16163.1 - 3.4e-39 133.7 0.2 1.4e-38 131.7 0.0 1.9 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 CEH16163.1 - 2.9e-26 91.0 0.0 4.5e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 CEH16163.1 - 9.3e-24 82.7 0.8 2.4e-23 81.4 0.6 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CEH16163.1 - 1.1e-18 66.3 0.9 2.3e-18 65.2 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CEH16163.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 CEH16163.1 - 0.0016 18.0 0.2 0.0089 15.6 0.0 2.0 2 0 0 2 2 2 1 MoeZ/MoeB domain ApbA PF02558.11 CEH16163.1 - 0.025 14.0 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 CEH16163.1 - 0.06 12.2 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 CEH16165.1 - 0.00093 18.1 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Retrotrans_gag PF03732.12 CEH16166.1 - 3.3e-06 27.0 1.7 9.7e-06 25.5 0.6 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_3 PF14244.1 CEH16166.1 - 0.028 13.9 0.1 0.06 12.9 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MIP PF00230.15 CEH16168.1 - 1.6e-40 138.9 12.8 2.2e-40 138.5 8.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3356 PF11836.3 CEH16171.1 - 0.04 13.7 0.6 0.083 12.6 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3356) Mito_fiss_reg PF05308.6 CEH16171.1 - 0.25 10.6 11.8 0.47 9.7 8.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DEC-1_N PF04625.8 CEH16171.1 - 2.7 6.5 13.7 4.2 5.9 9.5 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region GTP_EFTU PF00009.22 CEH16173.1 - 1.1e-41 142.3 0.0 1.6e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEH16173.1 - 1.6e-06 28.0 0.0 1.2e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CEH16173.1 - 0.00013 21.5 0.2 0.00032 20.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 CEH16173.1 - 0.00016 21.6 0.5 0.00062 19.8 0.3 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 CEH16173.1 - 0.00032 20.8 0.0 0.00066 19.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Miro PF08477.8 CEH16173.1 - 0.011 16.2 0.0 0.05 14.0 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein MobB PF03205.9 CEH16173.1 - 0.041 13.5 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 CEH16173.1 - 0.11 11.7 0.0 2.3 7.4 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CEH16173.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Dynamin family SLAC1 PF03595.12 CEH16175.1 - 3.1e-52 177.2 45.5 1.5e-51 174.9 31.5 1.8 1 1 0 1 1 1 1 Voltage-dependent anion channel WD40 PF00400.27 CEH16176.1 - 2.5e-21 74.7 5.4 4e-07 29.6 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Lgl_C PF08596.5 CEH16176.1 - 0.1 11.0 0.0 0.23 9.8 0.0 1.5 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CEH16177.1 - 1e-18 66.3 18.5 5.4e-07 29.2 0.3 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.1 CEH16177.1 - 0.075 13.3 1.1 0.48 10.7 0.1 2.8 2 0 0 2 2 2 0 PQQ-like domain DUF4611 PF15387.1 CEH16179.1 - 0.31 11.2 5.0 13 6.0 3.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Macoilin PF09726.4 CEH16179.1 - 0.77 7.9 11.4 1.7 6.8 7.9 1.5 1 1 0 1 1 1 0 Transmembrane protein Ribosomal_60s PF00428.14 CEH16179.1 - 2.4 8.6 8.1 1.1 9.7 3.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein SAP PF02037.22 CEH16180.1 - 0.00046 19.6 0.1 0.0012 18.3 0.1 1.8 1 0 0 1 1 1 1 SAP domain Pilin_PilA PF14245.1 CEH16180.1 - 0.031 14.7 7.1 0.086 13.3 4.9 1.9 1 1 0 1 1 1 0 Type IV pilin PilA TEBP_beta PF07404.6 CEH16180.1 - 1.4 7.9 16.2 2.2 7.3 11.2 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) HAUS6_N PF14661.1 CEH16180.1 - 9.4 5.5 8.4 0.65 9.3 1.7 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus GHMP_kinases_N PF00288.21 CEH16181.1 - 9.4e-07 28.8 3.0 9.4e-07 28.8 2.1 2.4 3 0 0 3 3 3 1 GHMP kinases N terminal domain DUF2780 PF11075.3 CEH16181.1 - 0.26 11.3 0.0 0.26 11.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) RRM_1 PF00076.17 CEH16182.1 - 4e-13 48.7 0.0 4.1e-05 23.1 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH16182.1 - 4.3e-12 45.8 0.0 2.2e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH16182.1 - 8.6e-08 31.9 0.1 5.6e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1275 PF06912.6 CEH16183.1 - 5.8e-18 64.8 20.2 1.5e-12 47.2 5.3 2.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1275) Phage_holin_3 PF05106.7 CEH16183.1 - 0.013 15.5 0.2 0.013 15.5 0.2 2.6 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) DUF3816 PF12822.2 CEH16183.1 - 0.72 9.7 4.4 2.4 8.0 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Cwf_Cwc_15 PF04889.7 CEH16186.1 - 1.1e-62 211.9 19.4 1.3e-62 211.6 13.5 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TATR PF03430.8 CEH16186.1 - 0.78 8.3 9.5 1 7.9 6.6 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator SGT1 PF07093.6 CEH16186.1 - 3.6 5.8 17.8 4.3 5.6 12.3 1.1 1 0 0 1 1 1 0 SGT1 protein Macoilin PF09726.4 CEH16186.1 - 5.8 5.0 12.7 7 4.7 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Rax2 PF12768.2 CEH16187.1 - 1.4e-70 237.7 0.6 3.6e-58 196.9 0.0 6.3 5 1 2 7 7 7 6 Cortical protein marker for cell polarity SH3_1 PF00018.23 CEH16187.1 - 9.1e-11 40.9 0.1 5.1e-10 38.5 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CEH16187.1 - 4.5e-08 32.5 0.0 1.3e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Kelch_4 PF13418.1 CEH16187.1 - 2.3e-05 24.0 2.5 7.5 6.4 0.0 6.6 6 0 0 6 6 6 1 Galactose oxidase, central domain SH3_2 PF07653.12 CEH16187.1 - 0.0022 17.4 0.0 0.0052 16.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PQQ_3 PF13570.1 CEH16187.1 - 0.04 14.2 9.9 0.9 9.9 0.2 6.4 5 0 0 5 5 5 0 PQQ-like domain DUF3330 PF11809.3 CEH16188.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) TPR_11 PF13414.1 CEH16191.1 - 4.2e-06 26.3 8.7 0.37 10.4 0.1 6.2 5 1 0 6 6 6 2 TPR repeat TPR_12 PF13424.1 CEH16191.1 - 0.00025 20.9 9.6 5.2 7.0 0.0 6.7 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEH16191.1 - 0.0006 20.4 19.6 1.8 9.3 0.1 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CEH16191.1 - 0.0055 16.4 7.3 4.4 7.0 0.1 5.8 6 1 0 6 6 6 1 Mad3/BUB1 homology region 1 TPR_14 PF13428.1 CEH16191.1 - 0.02 15.4 28.2 35 5.4 0.1 11.4 10 4 3 13 13 13 0 Tetratricopeptide repeat HAT PF02184.11 CEH16191.1 - 4.3 7.1 20.2 3.9 7.2 0.2 6.8 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat TPR_2 PF07719.12 CEH16191.1 - 4.5 7.4 22.7 4.1 7.5 0.0 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat zf-U1 PF06220.7 CEH16192.1 - 1.8e-05 24.1 0.1 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 U1 zinc finger ATG22 PF11700.3 CEH16194.1 - 6e-119 397.6 21.4 6.9e-119 397.4 14.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 CEH16194.1 - 2.8e-10 39.4 34.9 8.7e-05 21.3 0.8 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily TcpE PF12648.2 CEH16194.1 - 0.24 11.5 8.1 0.063 13.4 2.4 2.4 2 0 0 2 2 2 0 TcpE family TRAM_LAG1_CLN8 PF03798.11 CEH16197.1 - 1.3e-42 145.6 14.0 1.9e-42 145.0 9.7 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 CEH16197.1 - 2e-09 36.8 0.0 1.3e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 TRAM1-like protein DUF1675 PF07897.6 CEH16198.1 - 0.62 9.8 11.4 0.74 9.6 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Peptidase_A21 PF03566.8 CEH16198.1 - 4.2 5.3 8.6 5.5 4.9 6.0 1.2 1 0 0 1 1 1 0 Peptidase family A21 Oxidored_q6 PF01058.17 CEH16199.1 - 4.1e-21 74.9 0.1 6.5e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit ANTH PF07651.11 CEH16200.1 - 1.2e-50 171.7 0.0 1.5e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 CEH16200.1 - 1.5e-07 31.3 0.0 2.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 CEH16200.1 - 8.8e-05 22.4 35.3 8.8e-05 22.4 24.5 7.6 2 1 2 4 4 4 2 Domain of unknown function (DUF1720) VHS PF00790.14 CEH16200.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain Bax1-I PF01027.15 CEH16201.1 - 2.1e-36 125.4 25.4 2.5e-36 125.2 17.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 OSCP PF00213.13 CEH16202.1 - 3.1e-36 124.8 0.1 3.7e-36 124.5 0.1 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit NAP PF00956.13 CEH16203.1 - 5.3e-87 290.9 5.2 5.3e-87 290.9 3.6 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Peptidase_C54 PF03416.14 CEH16204.1 - 1.2e-80 270.5 0.0 2.4e-79 266.3 0.0 2.4 1 1 0 1 1 1 1 Peptidase family C54 SF3b1 PF08920.5 CEH16206.1 - 5.1e-36 123.8 1.4 2.8e-35 121.4 0.0 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 CEH16206.1 - 2.4e-18 66.1 6.0 1.5e-05 25.2 0.1 7.3 6 2 2 9 9 9 5 HEAT repeats HEAT_EZ PF13513.1 CEH16206.1 - 3.9e-11 43.0 6.9 0.14 12.6 0.1 8.3 7 2 2 9 9 9 3 HEAT-like repeat HEAT PF02985.17 CEH16206.1 - 1.5e-10 40.2 5.2 0.16 12.0 0.1 9.3 9 0 0 9 9 9 1 HEAT repeat Adaptin_N PF01602.15 CEH16206.1 - 4.9e-07 28.4 0.3 0.00098 17.5 0.1 4.0 1 1 1 2 2 2 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CEH16206.1 - 6.4e-06 26.4 2.1 1.3 9.4 0.0 5.0 6 0 0 6 6 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CEH16206.1 - 0.0003 20.2 0.9 0.12 11.6 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal TIP120 PF08623.5 CEH16206.1 - 0.00039 20.0 0.7 1.2 8.7 0.0 3.4 4 0 0 4 4 4 2 TATA-binding protein interacting (TIP20) ParcG PF10274.4 CEH16206.1 - 0.0057 16.5 0.2 1.9 8.3 0.0 3.8 2 2 1 3 3 3 1 Parkin co-regulated protein MMS19_N PF14500.1 CEH16206.1 - 0.014 14.6 0.5 11 5.2 0.0 4.0 4 1 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Dopey_N PF04118.9 CEH16206.1 - 0.084 11.6 0.2 0.68 8.6 0.0 2.5 2 0 0 2 2 2 0 Dopey, N-terminal MMS19_C PF12460.3 CEH16206.1 - 0.13 10.9 0.0 4.9 5.7 0.0 3.3 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal OS-D PF03392.8 CEH16207.1 - 0.018 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D DUF2340 PF10209.4 CEH16208.1 - 3.1e-39 133.9 0.2 3.8e-39 133.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) RNase_PH PF01138.16 CEH16209.1 - 2.6e-11 43.9 0.0 4.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 FAD_binding_3 PF01494.14 CEH16213.1 - 2.2e-23 82.8 0.0 4.3e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEH16213.1 - 2.9e-08 33.0 0.4 3.1e-06 26.3 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEH16213.1 - 5.4e-05 23.1 0.2 0.00018 21.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CEH16213.1 - 0.00062 20.1 0.1 0.017 15.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CEH16213.1 - 0.0011 17.9 0.1 0.0014 17.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 CEH16213.1 - 0.0024 16.7 0.0 0.64 8.7 0.0 2.7 3 0 0 3 3 3 1 Squalene epoxidase FAD_oxidored PF12831.2 CEH16213.1 - 0.0028 16.8 0.5 0.0049 16.0 0.3 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CEH16213.1 - 0.0042 15.6 0.5 0.0084 14.6 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 CEH16213.1 - 0.005 16.7 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CEH16213.1 - 0.026 13.1 0.5 4.2 5.8 0.1 2.4 3 0 0 3 3 3 0 Tryptophan halogenase 3HCDH_N PF02737.13 CEH16213.1 - 0.044 13.4 0.0 0.044 13.4 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CEH16213.1 - 0.097 11.4 4.4 0.37 9.5 3.0 2.1 1 1 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 CEH16213.1 - 0.1 12.3 0.2 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.11 CEH16213.1 - 0.16 11.3 0.1 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 CEH16213.1 - 0.45 10.9 2.1 0.47 10.9 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pescadillo_N PF06732.6 CEH16214.1 - 8.5e-111 369.7 0.2 2e-110 368.5 0.0 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 CEH16214.1 - 0.044 13.9 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain ALMS_motif PF15309.1 CEH16214.1 - 0.11 12.3 9.0 0.26 11.1 6.2 1.6 1 0 0 1 1 1 0 ALMS motif FAD_binding_4 PF01565.18 CEH16215.1 - 4.7e-27 94.1 1.7 1e-26 93.0 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CEH16215.1 - 4.6e-14 52.0 0.3 1.1e-13 50.8 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like tRNA-synt_1b PF00579.20 CEH16216.1 - 2.7e-21 75.9 0.1 1.3e-20 73.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) F1F0-ATPsyn_F PF10791.4 CEH16217.1 - 3.1e-24 85.0 0.1 6.4e-24 84.0 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Iso_dh PF00180.15 CEH16218.1 - 8.5e-90 301.1 0.0 5.6e-89 298.4 0.0 1.8 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Mur_ligase_M PF08245.7 CEH16219.1 - 5.6e-05 23.2 0.0 0.00023 21.2 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Ribosomal_S25 PF03297.10 CEH16220.1 - 1.3e-40 137.6 3.4 1.6e-40 137.4 2.4 1.1 1 0 0 1 1 1 1 S25 ribosomal protein Luteo_Vpg PF01659.11 CEH16220.1 - 0.047 13.3 0.2 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein BioT2 PF15368.1 CEH16220.1 - 0.068 12.9 2.6 0.072 12.8 1.5 1.3 1 1 0 1 1 1 0 Spermatogenesis family BioT2 PulS_OutS PF09691.5 CEH16220.1 - 0.088 12.8 1.0 0.16 11.9 0.5 1.6 1 1 1 2 2 2 0 Bacterial chaperone lipoprotein (PulS_OutS) DDRGK PF09756.4 CEH16220.1 - 0.15 11.4 0.7 0.26 10.7 0.5 1.3 1 1 0 1 1 1 0 DDRGK domain Mt_ATP-synt_D PF05873.7 CEH16221.1 - 4.7e-12 45.8 0.2 5.5e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF2408 PF10303.4 CEH16221.1 - 0.015 15.4 1.2 0.035 14.2 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Peptidase_M17_N PF02789.12 CEH16221.1 - 0.023 14.4 0.7 0.055 13.2 0.1 1.8 1 1 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Bacillus_HBL PF05791.6 CEH16221.1 - 0.042 13.2 0.3 0.11 11.9 0.1 1.8 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Dor1 PF04124.7 CEH16221.1 - 0.044 12.2 1.7 0.048 12.1 1.2 1.1 1 0 0 1 1 1 0 Dor1-like family DUF724 PF05266.9 CEH16221.1 - 0.064 12.8 1.7 0.1 12.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.7 CEH16221.1 - 0.076 12.8 0.2 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IL3 PF02059.10 CEH16221.1 - 0.091 12.7 1.3 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 Interleukin-3 Borrelia_lipo_2 PF06238.6 CEH16221.1 - 0.11 12.5 0.3 0.56 10.2 0.2 1.8 1 1 1 2 2 2 0 Borrelia burgdorferi BBR25 lipoprotein Prominin PF05478.6 CEH16221.1 - 0.16 9.4 1.2 0.18 9.3 0.8 1.0 1 0 0 1 1 1 0 Prominin Phage_GP20 PF06810.6 CEH16221.1 - 0.39 10.1 5.4 0.79 9.1 0.6 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Cauli_AT PF03233.8 CEH16221.1 - 0.42 10.3 2.4 1.1 8.9 1.7 1.7 1 1 0 1 1 1 0 Aphid transmission protein Tropomyosin PF00261.15 CEH16221.1 - 0.42 9.6 7.6 2.7 7.0 0.6 2.1 1 1 0 2 2 2 0 Tropomyosin DUF1366 PF07104.6 CEH16221.1 - 0.45 10.1 4.1 0.59 9.7 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1366) Prefoldin_2 PF01920.15 CEH16221.1 - 0.48 10.2 4.2 0.54 10.0 0.5 2.2 1 1 0 1 1 1 0 Prefoldin subunit Con-6 PF10346.4 CEH16221.1 - 0.52 9.7 2.0 5 6.6 0.0 2.5 2 0 0 2 2 2 0 Conidiation protein 6 Seryl_tRNA_N PF02403.17 CEH16221.1 - 0.76 9.8 6.0 1.1 9.3 3.5 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIVA PF05103.8 CEH16221.1 - 1.6 8.7 7.0 3.8 7.5 4.8 1.6 1 1 0 1 1 1 0 DivIVA protein PBS_linker_poly PF00427.16 CEH16222.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Mating_N PF12731.2 CEH16224.1 - 0.12 12.2 0.3 0.42 10.5 0.1 1.8 1 1 0 2 2 2 0 Mating-type protein beta 1 ATP-sulfurylase PF01747.12 CEH16225.1 - 1.9e-85 285.5 0.1 2.6e-85 285.1 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 CEH16225.1 - 5.7e-56 188.5 0.0 8.6e-56 187.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 CEH16225.1 - 6.1e-55 184.9 0.0 1e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain PH PF00169.24 CEH16226.1 - 0.0002 21.5 0.1 0.00085 19.4 0.0 2.0 2 0 0 2 2 2 1 PH domain CBM_20 PF00686.14 CEH16227.1 - 0.025 14.1 0.1 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Starch binding domain Pkinase PF00069.20 CEH16228.1 - 9.7e-17 60.9 0.0 1.1e-15 57.5 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH16228.1 - 4.9e-05 22.5 0.0 0.00033 19.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CEH16228.1 - 0.0048 16.6 0.1 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CEH16228.1 - 0.041 12.7 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Bromodomain PF00439.20 CEH16230.1 - 3.3e-22 78.2 0.0 6.3e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 CEH16230.1 - 3.7e-10 39.6 0.1 2.1e-09 37.2 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEH16230.1 - 3.8e-10 39.7 0.2 1.1e-08 35.0 0.3 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CEH16230.1 - 0.091 12.7 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAT1 PF09770.4 CEH16231.1 - 0.022 13.0 42.3 0.03 12.5 29.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.27 CEH16232.1 - 2.7e-28 96.7 7.5 1.9e-08 33.8 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 CEH16232.1 - 2.4e-19 69.6 0.0 4.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CEH16232.1 - 2.2e-09 37.0 0.0 4.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Nucleoporin_N PF08801.6 CEH16232.1 - 6.6e-08 31.7 0.3 0.013 14.3 0.1 4.1 3 2 0 3 3 3 2 Nup133 N terminal like DNA_binding_1 PF01035.15 CEH16232.1 - 0.025 14.2 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain SecY PF00344.15 CEH16234.1 - 1e-92 310.7 8.0 1.2e-92 310.4 5.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CEH16234.1 - 8.9e-18 63.5 0.3 3.8e-17 61.4 0.2 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p CBM_4_9 PF02018.12 CEH16235.1 - 0.047 13.6 0.1 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain EB PF01683.13 CEH16235.1 - 1.3 9.1 35.3 0.17 12.0 2.7 3.9 1 1 2 3 3 3 0 EB module UPF0506 PF11703.3 CEH16235.1 - 2.3 8.2 36.1 0.82 9.6 9.8 4.3 3 2 0 3 3 3 0 UPF0506 zf-H2C2_2 PF13465.1 CEH16236.1 - 3.3e-12 46.0 14.9 5.3e-07 29.6 0.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 CEH16236.1 - 2.9e-11 43.0 18.0 0.0017 18.5 2.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH16236.1 - 1.2e-09 37.7 15.7 0.0028 17.8 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CEH16236.1 - 0.0011 19.0 6.1 1.1 9.5 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CEH16236.1 - 0.0012 18.6 9.7 0.0023 17.7 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEH16236.1 - 0.075 13.2 6.4 0.51 10.5 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CEH16236.1 - 0.086 12.6 3.6 3.8 7.3 0.1 2.5 1 1 1 2 2 2 0 BED zinc finger C1_4 PF07975.7 CEH16236.1 - 0.53 10.3 3.8 1.9 8.5 2.6 1.9 1 1 0 1 1 1 0 TFIIH C1-like domain zf-trcl PF13451.1 CEH16236.1 - 0.54 9.9 3.0 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 Probable zinc-binding domain IBR PF01485.16 CEH16236.1 - 0.7 9.8 5.7 5.6 6.9 3.9 2.1 1 1 0 1 1 1 0 IBR domain XPA_N PF01286.13 CEH16236.1 - 1.2 8.8 2.7 30 4.4 0.3 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 CEH16236.1 - 7.1 6.6 7.5 4.4 7.3 2.4 2.5 2 1 0 2 2 2 0 Zinc ribbon domain Pkinase PF00069.20 CEH16237.1 - 9.6e-29 100.3 0.0 2.4e-24 85.8 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CEH16237.1 - 2.6e-14 52.9 0.0 6.9e-12 44.9 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CEH16237.1 - 1.6e-08 33.9 0.0 2.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEH16237.1 - 0.0026 16.8 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosom_S12_S23 PF00164.20 CEH16238.1 - 3.9e-39 132.8 0.7 4.5e-39 132.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L27e PF01777.13 CEH16239.1 - 3.9e-33 113.4 0.6 4.9e-33 113.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CEH16239.1 - 0.074 12.8 0.1 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 KOW motif SNF2_N PF00176.18 CEH16240.1 - 1.8e-67 227.2 0.0 2.6e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 CEH16240.1 - 1.7e-23 82.6 0.0 7.3e-21 74.0 0.0 2.6 2 0 0 2 2 2 2 HIRAN domain Helicase_C PF00271.26 CEH16240.1 - 5.1e-13 48.6 0.0 1.4e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 CEH16240.1 - 5.4e-06 25.9 13.3 9.6e-06 25.1 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH16240.1 - 9.7e-05 21.9 16.6 0.00017 21.1 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH16240.1 - 0.00012 21.9 16.3 0.00022 21.1 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEH16240.1 - 0.00047 19.9 14.7 0.00086 19.0 10.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CEH16240.1 - 0.012 15.3 15.7 0.02 14.6 10.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain RNase_T PF00929.19 CEH16241.1 - 9.2e-27 94.3 0.0 1.4e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF3552 PF12072.3 CEH16242.1 - 0.00034 19.8 3.8 0.00034 19.8 2.6 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3552) Pectinesterase PF01095.14 CEH16246.1 - 1.1e-07 30.7 0.1 1.9e-07 29.9 0.1 1.5 1 1 0 1 1 1 1 Pectinesterase Glyco_hydro_92 PF07971.7 CEH16247.1 - 1.6e-122 409.7 0.0 2.7e-122 409.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF3844 PF12955.2 CEH16248.1 - 1.6e-26 92.3 3.1 2.5e-26 91.7 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) PX PF00787.19 CEH16249.1 - 4.9e-23 81.0 0.2 7.2e-23 80.5 0.2 1.3 1 0 0 1 1 1 1 PX domain LysM PF01476.15 CEH16251.1 - 0.00027 20.7 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 LysM domain Ras PF00071.17 CEH16252.1 - 1.8e-46 157.4 0.5 2.4e-46 157.0 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH16252.1 - 1.3e-14 54.7 0.1 2.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH16252.1 - 5.8e-08 32.1 0.0 8e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEH16252.1 - 8.2e-07 28.6 0.3 5.7e-06 25.8 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEH16252.1 - 6.8e-06 26.0 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEH16252.1 - 0.00022 20.5 0.1 0.0037 16.5 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 CEH16252.1 - 0.00042 19.5 0.0 0.00058 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 CEH16252.1 - 0.019 14.6 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_35 PF14516.1 CEH16252.1 - 0.094 11.3 0.0 0.23 10.0 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain ATP_bind_3 PF01171.15 CEH16253.1 - 1.1e-14 54.4 0.0 1.8e-14 53.6 0.0 1.4 1 1 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 CEH16253.1 - 0.16 12.2 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) RecR PF02132.10 CEH16253.1 - 0.28 10.6 5.7 0.066 12.6 0.6 2.4 3 0 0 3 3 3 0 RecR protein Pkinase PF00069.20 CEH16254.1 - 6.1e-65 218.9 0.0 8.6e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH16254.1 - 3.2e-36 124.7 0.0 5.8e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH16254.1 - 2.1e-05 23.6 0.0 3.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEH16254.1 - 0.02 14.6 6.4 0.09 12.4 0.1 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3584 PF12128.3 CEH16254.1 - 1.1 6.4 17.5 1.8 5.7 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lin-8 PF03353.10 CEH16254.1 - 5.2 6.2 11.9 3.5 6.8 4.6 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Init_tRNA_PT PF04179.7 CEH16255.1 - 0.041 12.7 0.1 0.059 12.2 0.1 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase MCM PF00493.18 CEH16256.1 - 4.7e-129 429.9 0.0 6.7e-129 429.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CEH16256.1 - 5.5e-24 84.9 0.0 1.3e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CEH16256.1 - 6.7e-08 31.9 0.0 1.1e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CEH16256.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CEH16256.1 - 0.011 15.2 0.0 0.031 13.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain RRM_1 PF00076.17 CEH16257.1 - 5.9e-32 109.1 0.0 4.6e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH16257.1 - 5e-18 64.8 0.0 1.7e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH16257.1 - 2.2e-14 53.0 0.0 8.7e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 CEH16258.1 - 1.5e-20 73.2 14.6 1.5e-20 73.2 10.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Aminotran_3 PF00202.16 CEH16260.1 - 2.3e-77 260.1 0.0 2.9e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Spt5_N PF11942.3 CEH16261.1 - 1 10.0 7.3 2.5 8.7 5.0 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal 2-Hacid_dh_C PF02826.14 CEH16262.1 - 7.6e-45 152.2 0.0 1.3e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CEH16262.1 - 1.6e-22 79.4 0.0 2e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CEH16262.1 - 0.012 15.5 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CEH16262.1 - 0.11 12.6 0.0 0.82 9.7 0.0 2.4 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase IncA PF04156.9 CEH16263.1 - 0.027 14.0 85.6 1 8.9 9.2 5.4 2 2 3 5 5 5 0 IncA protein MAD PF05557.8 CEH16263.1 - 0.31 9.0 68.4 0.055 11.5 13.5 3.4 1 1 2 3 3 3 0 Mitotic checkpoint protein DUF2353 PF09789.4 CEH16263.1 - 1.9 7.6 52.7 2.5 7.2 5.5 4.4 2 2 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) APH PF01636.18 CEH16264.1 - 4.5e-19 69.1 0.0 1.1e-18 67.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family CAP_GLY PF01302.20 CEH16265.1 - 1e-15 57.1 0.3 1.8e-15 56.4 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Filament PF00038.16 CEH16265.1 - 1.3 8.4 92.8 0.035 13.5 0.3 5.3 2 2 2 4 4 4 0 Intermediate filament protein CBFD_NFYB_HMF PF00808.18 CEH16266.1 - 1.6e-12 47.3 0.2 3.2e-12 46.3 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEH16266.1 - 1.5e-05 25.0 0.2 2.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Herpes_Helicase PF02689.9 CEH16266.1 - 0.01 13.6 0.0 0.012 13.3 0.0 1.1 1 0 0 1 1 1 0 Helicase TFIID_30kDa PF03540.8 CEH16266.1 - 0.069 12.9 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Telomerase_RBD PF12009.3 CEH16267.1 - 8.8e-34 116.3 0.0 1.7e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CEH16267.1 - 2.4e-16 59.7 0.0 6.4e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0489 PF12640.2 CEH16269.1 - 0.0017 18.6 0.1 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 UPF0489 domain HSF_DNA-bind PF00447.12 CEH16270.1 - 2.5e-35 120.7 0.3 4.1e-35 120.0 0.2 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding PAP_RNA-bind PF04926.10 CEH16270.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain Macoilin PF09726.4 CEH16270.1 - 0.11 10.7 3.7 0.14 10.3 2.6 1.4 1 1 0 1 1 1 0 Transmembrane protein Ets PF00178.17 CEH16270.1 - 0.13 12.3 0.0 1.2 9.2 0.0 2.4 2 1 0 3 3 3 0 Ets-domain Ferric_reduct PF01794.14 CEH16271.1 - 6.1e-16 58.6 10.0 1.7e-15 57.2 6.4 2.2 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CEH16271.1 - 9.2e-16 57.6 0.0 2.5e-09 36.9 0.1 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 CEH16271.1 - 5.2e-07 29.6 0.0 0.0044 16.9 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Pkinase PF00069.20 CEH16272.1 - 5e-48 163.5 0.0 1.3e-47 162.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH16272.1 - 1.6e-23 83.1 0.0 7.5e-18 64.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEH16272.1 - 0.47 9.3 0.0 0.86 8.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like adh_short_C2 PF13561.1 CEH16273.1 - 9e-28 97.6 0.1 1.2e-27 97.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEH16273.1 - 4.2e-11 43.0 0.1 5.8e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH16273.1 - 0.00088 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1748 PF08520.5 CEH16275.1 - 1.5e-20 72.5 0.1 1.7e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PRKCSH-like PF12999.2 CEH16276.1 - 1.2e-49 168.2 6.4 1.8e-49 167.6 3.7 1.9 1 1 1 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CEH16276.1 - 5.9e-22 77.7 0.0 1.2e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CEH16276.1 - 1.4e-09 38.6 0.6 3.5e-09 37.3 0.4 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein APG6 PF04111.7 CEH16276.1 - 0.27 10.2 3.3 0.48 9.4 2.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Ldl_recept_a PF00057.13 CEH16276.1 - 3.9 7.4 20.5 0.21 11.4 3.0 3.3 2 1 1 3 3 3 0 Low-density lipoprotein receptor domain class A RabGAP-TBC PF00566.13 CEH16277.1 - 8.7e-19 67.8 0.0 1.8e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EPSP_synthase PF00275.15 CEH16278.1 - 7.3e-123 410.0 0.0 1.1e-122 409.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CEH16278.1 - 7.7e-94 313.4 1.0 1.4e-93 312.5 0.0 2.0 3 0 0 3 3 3 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CEH16278.1 - 2.2e-59 200.8 0.0 3.8e-59 200.0 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 CEH16278.1 - 8.6e-27 93.9 0.0 7.6e-26 90.8 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 CEH16278.1 - 4.8e-24 84.2 0.0 1.3e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CEH16278.1 - 7.2e-10 39.0 0.0 2e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.1 CEH16278.1 - 0.08 12.8 0.1 6.7 6.5 0.0 3.4 4 0 0 4 4 4 0 AAA domain Pkinase PF00069.20 CEH16279.1 - 3.1e-45 154.3 0.0 4.8e-34 117.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH16279.1 - 5.3e-16 58.4 0.0 4.4e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CEH16279.1 - 0.00055 19.7 0.0 0.00099 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEH16279.1 - 0.0018 17.2 0.0 0.0064 15.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CEH16279.1 - 0.011 14.7 0.1 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease PF00324.16 CEH16280.1 - 4.9e-117 391.1 44.0 5.6e-117 390.9 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEH16280.1 - 4e-31 108.0 48.0 5.1e-31 107.6 33.3 1.1 1 0 0 1 1 1 1 Amino acid permease Polysacc_deac_1 PF01522.16 CEH16282.1 - 4.7e-25 87.6 0.0 8.9e-25 86.7 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase FAD_binding_7 PF03441.9 CEH16283.1 - 6.1e-61 206.0 0.0 1.2e-60 205.0 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CEH16283.1 - 2.7e-20 72.7 0.0 4.7e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase RCR PF12273.3 CEH16284.1 - 2.2e-07 31.4 9.6 3.8e-07 30.7 6.6 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.5 CEH16284.1 - 0.014 14.6 0.5 0.019 14.2 0.3 1.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Lamp PF01299.12 CEH16284.1 - 0.042 13.0 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Josephin PF02099.12 CEH16285.1 - 1.1e-50 171.3 0.0 1.9e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Josephin UIM PF02809.15 CEH16285.1 - 0.0057 16.1 2.8 0.0057 16.1 2.0 5.6 6 0 0 6 6 6 3 Ubiquitin interaction motif Skp1_POZ PF03931.10 CEH16287.1 - 1.3e-09 37.9 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain adh_short PF00106.20 CEH16288.1 - 1.6e-05 24.9 0.2 0.15 11.9 0.0 3.7 4 0 0 4 4 4 2 short chain dehydrogenase SspP PF08179.7 CEH16288.1 - 0.0033 17.5 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 Small acid-soluble spore protein P family SIMPL PF04402.9 CEH16292.1 - 3.1e-27 95.8 3.8 3.5e-27 95.6 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) SpoVIF PF14069.1 CEH16292.1 - 0.21 11.3 0.8 0.48 10.1 0.2 1.8 2 0 0 2 2 2 0 Stage VI sporulation protein F SIR2 PF02146.12 CEH16294.1 - 1.8e-29 102.7 0.0 9.6e-18 64.5 0.0 2.1 2 0 0 2 2 2 2 Sir2 family MMR_HSR1 PF01926.18 CEH16296.1 - 3.6e-11 43.0 0.0 8e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEH16296.1 - 0.026 13.7 0.1 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B PmoA PF14100.1 CEH16296.1 - 0.036 13.2 0.5 0.07 12.3 0.4 1.4 1 0 0 1 1 1 0 Methane oxygenase PmoA Miro PF08477.8 CEH16296.1 - 0.038 14.4 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 CEH16296.1 - 0.041 13.0 0.4 0.12 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CEH16296.1 - 0.068 12.7 0.1 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.8 CEH16296.1 - 0.23 10.2 0.1 0.39 9.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 CEH16296.1 - 0.4 10.4 2.4 0.8 9.5 0.2 2.6 4 0 0 4 4 4 0 Dynamin family Not3 PF04065.10 CEH16297.1 - 5.5e-93 310.5 19.6 7.8e-93 310.0 13.6 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CEH16297.1 - 1.5e-34 118.7 8.5 1.5e-34 118.7 5.9 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin PF00804.20 CEH16297.1 - 0.0034 17.5 11.5 0.15 12.2 4.3 2.7 2 0 0 2 2 2 2 Syntaxin Poty_PP PF08440.5 CEH16297.1 - 0.14 11.1 3.0 0.22 10.5 2.1 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein UBA PF00627.26 CEH16298.1 - 5.7e-21 73.7 4.0 7.4e-13 47.9 0.0 2.8 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 CEH16298.1 - 2.4e-19 68.5 0.5 3.6e-19 67.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 CEH16298.1 - 8.7e-18 63.5 5.1 1.6e-17 62.6 3.5 1.4 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 CEH16298.1 - 2.1e-08 33.7 0.5 4.7e-08 32.6 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 CEH16298.1 - 0.0004 19.8 0.0 0.012 15.1 0.0 2.7 2 0 0 2 2 2 1 UBA-like domain CUE PF02845.11 CEH16298.1 - 0.0014 18.0 1.1 1.1 8.7 0.0 3.7 3 1 1 4 4 4 1 CUE domain Rad60-SLD_2 PF13881.1 CEH16298.1 - 0.0034 17.2 0.0 0.0076 16.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HBS1_N PF08938.5 CEH16298.1 - 0.0038 17.3 0.7 0.9 9.7 0.4 2.7 2 1 0 2 2 2 1 HBS1 N-terminus DUF2407 PF10302.4 CEH16298.1 - 0.0086 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Metal_resist PF13801.1 CEH16298.1 - 0.014 15.4 10.5 0.2 11.6 3.8 3.5 3 1 0 3 3 3 0 Heavy-metal resistance UBA_3 PF09288.5 CEH16298.1 - 0.092 12.3 0.0 20 4.8 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain p450 PF00067.17 CEH16299.1 - 3.2e-77 260.0 0.0 2e-76 257.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 ATG27 PF09451.5 CEH16300.1 - 2.2e-38 132.0 0.0 2.8e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 CEH16300.1 - 0.01 15.6 0.0 0.067 12.9 0.0 2.0 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat Peptidase_S64 PF08192.6 CEH16301.1 - 3.3 5.9 4.7 4.9 5.3 3.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF4385 PF14328.1 CEH16302.1 - 1e-51 174.6 0.1 1e-51 174.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4385) ParA PF10609.4 CEH16303.1 - 4.3e-24 84.1 0.1 8.4e-24 83.2 0.1 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CEH16303.1 - 1.9e-13 50.2 0.1 5.2e-13 48.8 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CEH16303.1 - 4.9e-05 22.5 8.7 0.00033 19.7 1.6 2.9 2 1 1 3 3 3 2 Anion-transporting ATPase AAA_31 PF13614.1 CEH16303.1 - 0.00024 21.0 0.9 0.00055 19.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CEH16303.1 - 0.0012 18.0 0.3 0.0058 15.7 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.1 CEH16303.1 - 0.0039 16.6 0.3 0.0079 15.6 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH16303.1 - 0.37 10.5 5.1 4.9 6.9 0.2 2.4 2 0 0 2 2 2 0 Part of AAA domain Fer4_NifH PF00142.13 CEH16303.1 - 4.7 6.3 5.8 1.7 7.8 0.1 2.7 3 1 0 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family GFO_IDH_MocA PF01408.17 CEH16304.1 - 6.3e-15 55.7 0.4 2.4e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DUF3584 PF12128.3 CEH16304.1 - 0.052 10.8 31.5 0.082 10.2 21.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2951 PF11166.3 CEH16304.1 - 0.18 11.6 11.7 1.1 9.1 1.4 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF2951) BBP1_C PF15272.1 CEH16304.1 - 3.2 7.2 14.6 2 7.9 8.4 1.9 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal SPC22 PF04573.7 CEH16305.1 - 1.9e-39 134.6 0.1 2.1e-39 134.5 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit BolA PF01722.13 CEH16306.1 - 1.3e-29 101.9 0.4 1.5e-29 101.7 0.2 1.0 1 0 0 1 1 1 1 BolA-like protein WD40 PF00400.27 CEH16307.1 - 3e-18 64.9 2.9 1e-07 31.5 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 CEH16307.1 - 0.043 11.9 0.0 0.088 10.9 0.0 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Aldo_ket_red PF00248.16 CEH16308.1 - 1.7e-65 220.6 0.0 2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_11 PF13414.1 CEH16310.1 - 7.2e-22 76.8 20.2 1.1e-11 44.2 0.4 5.7 3 3 3 7 7 7 6 TPR repeat DnaJ PF00226.26 CEH16310.1 - 3.7e-20 71.4 1.5 8.1e-20 70.3 0.1 2.4 3 0 0 3 3 2 1 DnaJ domain TPR_16 PF13432.1 CEH16310.1 - 7.3e-20 71.1 29.1 4.3e-09 36.7 1.1 5.7 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 CEH16310.1 - 3.6e-17 60.8 22.2 0.0039 17.0 0.1 7.7 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 CEH16310.1 - 7.7e-16 56.9 15.8 0.00051 19.5 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 CEH16310.1 - 1.5e-15 57.2 24.1 3.3e-05 24.1 0.5 5.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CEH16310.1 - 4.4e-13 48.3 11.1 0.0091 16.1 0.0 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CEH16310.1 - 5.8e-13 48.2 21.7 0.0044 17.5 0.8 7.5 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 CEH16310.1 - 6.7e-10 38.6 17.4 1.4e-05 24.8 0.6 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEH16310.1 - 7.5e-09 35.3 13.0 0.035 13.9 0.1 7.2 6 2 2 8 8 8 3 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 CEH16310.1 - 1.5e-06 27.5 14.7 0.23 11.3 0.4 6.9 6 2 2 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 CEH16310.1 - 0.00013 22.0 16.5 0.0051 16.9 1.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CEH16310.1 - 0.0008 19.7 16.3 0.24 11.9 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_20 PF14561.1 CEH16310.1 - 0.012 15.6 16.3 0.92 9.6 0.2 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEH16310.1 - 0.013 15.4 21.1 0.089 12.7 1.7 5.1 5 1 1 6 6 5 0 Tetratricopeptide repeat Cytochrom_B562 PF07361.6 CEH16310.1 - 0.044 14.1 2.0 0.044 14.1 1.4 3.1 4 0 0 4 4 2 0 Cytochrome b562 TPR_4 PF07721.9 CEH16310.1 - 0.092 13.2 13.6 3.7 8.2 2.4 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 CEH16310.1 - 1.3 9.2 17.3 0.76 10.0 0.4 4.6 2 2 2 5 5 5 0 Bacterial transcriptional activator domain Rho_Binding PF08912.6 CEH16310.1 - 6.6 7.1 11.9 0.1 12.9 1.8 2.7 2 1 1 3 3 3 0 Rho Binding DUF2428 PF10350.4 CEH16311.1 - 1.1e-48 165.4 0.1 2.2e-48 164.5 0.1 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) PIGA PF08288.7 CEH16311.1 - 1e-41 141.1 0.2 2.9e-41 139.7 0.1 1.9 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CEH16311.1 - 5.8e-25 87.6 0.0 1.2e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CEH16311.1 - 1.5e-18 67.1 0.8 1.5e-18 67.1 0.6 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CEH16311.1 - 2.7e-15 56.8 0.7 2.7e-15 56.8 0.5 3.9 4 0 0 4 4 4 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CEH16311.1 - 2e-11 44.2 0.0 4.9e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CEH16311.1 - 6.9e-07 29.1 0.1 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like HEAT PF02985.17 CEH16311.1 - 2.1e-05 24.2 12.8 0.39 10.9 0.0 7.8 7 1 1 8 8 7 1 HEAT repeat Glyco_trans_1_2 PF13524.1 CEH16311.1 - 0.0048 17.1 0.1 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Vac14_Fab1_bd PF12755.2 CEH16311.1 - 0.043 14.2 0.0 3.3 8.1 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 CEH16311.1 - 0.15 10.3 0.4 0.93 7.7 0.0 2.3 3 0 0 3 3 3 0 Adaptin N terminal region Oxysterol_BP PF01237.13 CEH16313.1 - 3.3e-113 377.8 0.0 5.5e-113 377.0 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank PF00023.25 CEH16313.1 - 2.7e-15 55.2 0.0 8.4e-06 25.3 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 CEH16313.1 - 4.5e-14 52.5 0.1 4.4e-09 36.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEH16313.1 - 2.2e-13 49.9 0.1 4.8e-06 26.6 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH16313.1 - 4.3e-10 38.8 0.0 0.014 15.5 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 CEH16313.1 - 2.9e-09 37.1 0.1 0.00048 20.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.24 CEH16313.1 - 1.1e-08 35.2 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CEH16313.1 - 3.5e-08 33.6 0.1 8.2e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 CEH16313.1 - 0.0039 17.2 0.1 0.0091 16.0 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain LMWPc PF01451.16 CEH16314.1 - 0.097 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase Glyco_hydro_3 PF00933.16 CEH16315.1 - 1.1e-72 244.5 0.0 1.7e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CEH16315.1 - 8.7e-46 156.2 0.0 1.4e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CEH16315.1 - 4.5e-26 90.5 0.1 1.2e-25 89.2 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain C2 PF00168.25 CEH16316.1 - 7.6e-12 44.9 0.0 4.3e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 C2 domain NT-C2 PF10358.4 CEH16316.1 - 0.0077 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins 5_nucleotid_C PF02872.13 CEH16317.1 - 2.5e-32 111.9 0.0 8.6e-25 87.5 0.0 2.7 3 0 0 3 3 3 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 CEH16317.1 - 4.8e-08 32.6 0.0 9.3e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.11 CEH16318.1 - 2e-27 95.8 30.1 2e-27 95.8 20.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DNA_processg_A PF02481.10 CEH16318.1 - 0.015 14.2 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A SNF2_N PF00176.18 CEH16319.1 - 3.3e-62 209.9 0.0 4.8e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEH16319.1 - 1.9e-13 50.0 0.2 5e-13 48.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH16319.1 - 5.2e-08 32.9 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CEH16319.1 - 8e-05 22.1 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase EMG1 PF03587.9 CEH16320.1 - 1.4e-74 249.7 0.0 1.8e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase HMG_box PF00505.14 CEH16321.1 - 6.5e-16 58.3 0.6 6.5e-16 58.3 0.4 2.7 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEH16321.1 - 1.2e-12 48.0 0.7 1.2e-12 48.0 0.5 2.1 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.8 CEH16321.1 - 0.0023 18.1 0.5 0.0023 18.1 0.4 1.9 2 0 0 2 2 2 1 YABBY protein Metal_resist PF13801.1 CEH16321.1 - 0.69 9.9 13.2 1.5 8.8 1.9 3.2 3 0 0 3 3 3 0 Heavy-metal resistance Snf7 PF03357.16 CEH16322.1 - 3e-42 143.8 15.3 3e-42 143.8 10.6 2.0 1 1 1 2 2 2 1 Snf7 DUF2450 PF10475.4 CEH16322.1 - 0.5 9.2 6.6 0.69 8.7 3.8 1.7 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Atg14 PF10186.4 CEH16322.1 - 0.56 9.0 8.3 0.41 9.5 4.6 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_23 PF13476.1 CEH16322.1 - 4.4 7.5 8.6 11 6.3 5.9 1.6 1 1 0 1 1 1 0 AAA domain DUF724 PF05266.9 CEH16322.1 - 5.6 6.5 8.8 2.1 7.8 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.15 CEH16322.1 - 6.9 6.4 12.2 0.48 10.2 0.8 3.5 3 1 0 3 3 3 0 Prefoldin subunit CTP_transf_2 PF01467.21 CEH16323.1 - 1.5e-26 93.3 0.0 2.4e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase FAD_binding_1 PF00667.15 CEH16324.1 - 5.8e-53 179.5 0.0 8.2e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CEH16324.1 - 6.3e-08 33.1 0.0 1.5e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CEH16324.1 - 0.017 15.2 0.0 0.066 13.3 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain DoxX PF07681.7 CEH16325.1 - 2.4 8.6 4.6 0.42 11.0 0.7 1.7 2 0 0 2 2 2 0 DoxX NAD_kinase PF01513.16 CEH16328.1 - 1.4e-58 197.9 0.0 2.1e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase zf-rbx1 PF12678.2 CEH16329.1 - 5.8e-35 119.2 15.7 6.8e-35 119.0 10.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CEH16329.1 - 1.9e-17 62.8 12.0 2.4e-17 62.5 8.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CEH16329.1 - 6.7e-07 29.0 15.7 9.9e-07 28.4 8.9 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CEH16329.1 - 8.3e-05 22.1 9.8 0.026 14.2 6.6 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH16329.1 - 0.00034 20.2 12.2 0.0036 16.9 8.4 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH16329.1 - 0.015 15.2 14.1 0.38 10.8 9.6 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH16329.1 - 0.099 12.3 11.8 0.64 9.7 8.2 2.2 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 CEH16329.1 - 0.23 11.4 13.9 0.07 13.0 6.3 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CEH16329.1 - 0.72 9.6 7.6 20 5.0 5.3 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 CEH16329.1 - 1.2 9.2 11.7 2.4 8.2 8.1 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CEH16329.1 - 8.4 6.6 14.1 2.7e+02 1.7 9.8 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.1 CEH16329.1 - 9.2 6.2 9.2 0.44 10.4 0.5 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF3325 PF11804.3 CEH16330.1 - 1.3 9.0 4.3 0.44 10.4 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) LRR_4 PF12799.2 CEH16331.1 - 6.4e-11 41.6 24.3 1.6e-05 24.3 7.8 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEH16331.1 - 4e-09 36.0 18.1 4.7e-05 23.0 6.5 3.5 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 CEH16331.1 - 0.2 11.8 13.3 8 6.8 1.9 4.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 CEH16331.1 - 0.92 9.7 20.1 5.1 7.5 1.8 5.8 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 CEH16331.1 - 1.9 9.0 16.6 15 6.3 0.4 5.9 6 0 0 6 6 6 0 Leucine rich repeat Arrestin_N PF00339.24 CEH16332.1 - 4.4e-05 23.3 0.0 0.00027 20.7 0.0 2.3 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain DUF793 PF05633.6 CEH16332.1 - 0.26 9.9 0.5 0.44 9.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF793) PRA1 PF03208.14 CEH16333.1 - 8.4e-41 138.8 0.3 9.6e-41 138.6 0.2 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF3040 PF11239.3 CEH16333.1 - 0.055 13.5 0.1 0.055 13.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) MadM PF03818.8 CEH16333.1 - 0.14 11.6 1.8 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit PALP PF00291.20 CEH16334.1 - 4.6e-75 252.6 0.4 6.4e-75 252.2 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 CEH16334.1 - 2.6e-38 129.5 0.0 2.7e-24 84.5 0.0 3.1 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase Peripla_BP_6 PF13458.1 CEH16334.1 - 0.085 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein AMMECR1 PF01871.12 CEH16335.1 - 1.9e-44 150.8 0.0 2.3e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 MHYT PF03707.11 CEH16337.1 - 1.8e-07 31.1 23.7 3.5e-05 23.8 2.4 4.9 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat SNF2_N PF00176.18 CEH16338.1 - 8.7e-67 225.0 0.4 1.4e-66 224.3 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 CEH16338.1 - 5.8e-22 77.8 0.3 3.3e-21 75.4 0.2 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.19 CEH16338.1 - 1.3e-17 63.1 1.6 6.9e-13 48.0 0.3 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CEH16338.1 - 4.8e-15 55.1 0.0 2.1e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH16338.1 - 6.2e-07 29.4 0.0 2.3e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CEH16338.1 - 2.1e-05 24.0 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase KdpC PF02669.10 CEH16338.1 - 0.13 11.9 1.7 0.49 10.0 1.2 2.1 1 0 0 1 1 1 0 K+-transporting ATPase, c chain LRR_9 PF14580.1 CEH16339.1 - 1.6e-45 154.8 0.1 2e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CEH16339.1 - 2.6e-14 52.4 5.2 5.6e-07 29.0 0.9 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEH16339.1 - 7.8e-13 47.9 10.0 7.7e-07 28.7 0.3 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CEH16339.1 - 0.0016 18.2 3.3 8 6.9 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 CEH16339.1 - 0.002 18.0 2.4 3.3 8.3 0.0 4.4 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 CEH16339.1 - 0.073 13.1 2.0 3.2 8.0 0.0 4.0 4 1 0 4 4 4 0 Leucine Rich repeat DUF3656 PF12392.3 CEH16339.1 - 0.12 12.4 1.2 0.21 11.6 0.9 1.3 1 0 0 1 1 1 0 Collagenase cNMP_binding PF00027.24 CEH16340.1 - 3.4e-40 135.7 0.0 2.1e-19 69.1 0.0 2.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CEH16340.1 - 1.6e-11 43.4 0.7 3e-11 42.5 0.5 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit RPEL PF02755.10 CEH16341.1 - 1.3e-09 37.0 14.4 5.6e-07 28.6 1.1 3.5 3 1 0 3 3 3 2 RPEL repeat DUF247 PF03140.10 CEH16341.1 - 0.081 11.9 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function HTH_22 PF13309.1 CEH16341.1 - 0.15 11.8 0.2 16 5.3 0.0 2.3 2 0 0 2 2 2 0 HTH domain DUF1366 PF07104.6 CEH16341.1 - 0.26 10.9 2.2 0.36 10.4 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1366) L27_2 PF09045.5 CEH16341.1 - 1.4 8.5 4.6 0.54 9.8 0.4 2.2 2 1 0 2 2 2 0 L27_2 Pkinase PF00069.20 CEH16342.1 - 2.4e-34 118.6 0.0 4.3e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH16342.1 - 6.5e-13 48.3 0.0 3.6e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEH16342.1 - 0.00019 20.4 0.0 0.35 9.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like ADH_zinc_N PF00107.21 CEH16343.1 - 1.7e-33 114.9 0.0 3.8e-33 113.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH16343.1 - 7.8e-10 39.7 0.0 1.4e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH16343.1 - 2.7e-05 23.8 0.0 0.0001 22.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 CEH16343.1 - 0.00041 19.9 0.1 0.00072 19.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 CEH16343.1 - 0.038 13.9 0.2 0.072 13.0 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding HupF_HypC PF01455.13 CEH16343.1 - 0.087 12.8 0.6 0.28 11.1 0.1 2.2 2 1 0 2 2 2 0 HupF/HypC family Rhabdo_M2 PF04785.7 CEH16343.1 - 0.093 11.7 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Med14 PF08638.6 CEH16344.1 - 2.9e-43 147.3 0.0 4.6e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 CBP4 PF07960.6 CEH16345.1 - 3.4e-08 33.1 0.0 3.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 CBP4 DUF4414 PF14377.1 CEH16345.1 - 0.13 12.2 1.2 0.15 11.9 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) ADH_N PF08240.7 CEH16346.1 - 1e-30 105.6 0.4 2.3e-30 104.5 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEH16346.1 - 1.2e-22 79.8 0.0 2.2e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Rhodanese PF00581.15 CEH16346.1 - 9.4e-06 25.9 0.0 2.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain AlaDh_PNT_C PF01262.16 CEH16346.1 - 0.001 18.6 0.0 0.0033 17.0 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 CEH16346.1 - 0.0016 18.4 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_18 PF12847.2 CEH16346.1 - 0.11 13.1 0.1 0.47 11.0 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Alpha-amylase PF00128.19 CEH16347.1 - 1.6e-88 297.1 0.0 2.2e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain BRE1 PF08647.6 CEH16348.1 - 3.7e-18 65.2 8.9 3.7e-18 65.2 6.1 5.5 4 2 0 5 5 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 CEH16348.1 - 8.7e-07 28.8 10.6 1.4e-06 28.2 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEH16348.1 - 1.9e-06 27.4 8.9 3.4e-06 26.6 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH16348.1 - 8.6e-06 25.3 11.6 1.4e-05 24.6 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH16348.1 - 1.7e-05 24.4 10.9 2.7e-05 23.8 7.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 CEH16348.1 - 2.2e-05 24.1 2.8 4.1e-05 23.2 2.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 CEH16348.1 - 0.00064 19.4 9.8 0.0011 18.7 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CEH16348.1 - 0.012 15.4 7.8 0.026 14.3 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEH16348.1 - 0.015 14.9 3.9 0.037 13.7 2.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 CEH16348.1 - 0.52 10.4 5.0 0.99 9.5 3.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger PYC_OADA PF02436.13 CEH16348.1 - 0.95 8.8 8.4 1.2 8.5 0.2 2.8 2 0 0 2 2 2 0 Conserved carboxylase domain zf-RING_4 PF14570.1 CEH16348.1 - 2.5 7.7 9.4 7.4 6.2 6.6 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Gtr1_RagA PF04670.7 CEH16349.1 - 3e-85 285.0 0.0 4e-85 284.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CEH16349.1 - 0.00011 21.5 0.0 0.00022 20.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CEH16349.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH16349.1 - 0.0014 19.1 0.0 0.0045 17.4 0.0 1.9 1 1 1 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 CEH16349.1 - 0.0039 17.1 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CEH16349.1 - 0.03 13.8 0.3 0.097 12.1 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DASH_Spc19 PF08287.6 CEH16349.1 - 0.044 13.3 0.1 0.33 10.5 0.1 2.4 2 1 1 3 3 3 0 Spc19 ABC_tran PF00005.22 CEH16349.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CEH16349.1 - 0.2 11.2 0.4 0.45 10.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain X PF00739.14 CEH16351.1 - 0.037 13.9 0.3 0.041 13.8 0.2 1.1 1 0 0 1 1 1 0 Trans-activation protein X G-alpha PF00503.15 CEH16352.1 - 2.6e-131 437.9 2.3 3.1e-131 437.6 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEH16352.1 - 5e-17 61.6 2.2 5e-12 45.4 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 CEH16352.1 - 8.2e-05 22.0 0.1 0.00029 20.3 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.7 CEH16352.1 - 8.6e-05 21.7 4.4 0.024 13.7 3.1 2.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CEH16352.1 - 0.00034 21.0 0.0 0.48 10.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 CEH16352.1 - 0.009 15.9 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 CEH16352.1 - 0.0092 15.4 0.2 0.042 13.3 0.1 2.0 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 CEH16352.1 - 0.019 15.3 0.9 0.04 14.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CEH16352.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 CEH16352.1 - 0.026 13.9 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Carn_acyltransf PF00755.15 CEH16354.1 - 8.4e-165 549.2 0.0 1.1e-164 548.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3342 PF11822.3 CEH16354.1 - 0.13 11.4 0.1 0.43 9.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) Peptidase_M14 PF00246.19 CEH16355.1 - 6.5e-57 193.2 0.0 1.1e-56 192.4 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase RNA_polI_A14 PF08203.6 CEH16356.1 - 0.053 13.7 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Retrotrans_gag PF03732.12 CEH16357.1 - 2.7e-05 24.1 0.1 2.7e-05 24.1 0.1 2.1 2 1 0 2 2 2 1 Retrotransposon gag protein PNMA PF14893.1 CEH16357.1 - 0.019 13.9 1.3 0.025 13.6 0.9 1.2 1 0 0 1 1 1 0 PNMA MAT1 PF06391.8 CEH16357.1 - 0.19 11.2 4.6 0.28 10.7 3.2 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF4094 PF13334.1 CEH16357.1 - 0.19 12.1 3.2 0.46 10.8 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) ABC_tran_2 PF12848.2 CEH16357.1 - 0.62 9.9 8.9 1.6 8.6 6.2 1.7 1 0 0 1 1 1 0 ABC transporter rve PF00665.21 CEH16358.1 - 2.2e-22 79.4 0.0 7.7e-22 77.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEH16358.1 - 5.1e-14 52.1 0.8 1.8e-13 50.3 0.2 2.2 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CEH16358.1 - 5.1e-14 51.6 0.3 1e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 CEH16358.1 - 1.5e-07 31.0 1.0 3.4e-07 29.8 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 CEH16358.1 - 0.0064 15.9 2.6 0.016 14.6 1.8 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RVP PF00077.15 CEH16358.1 - 0.015 15.1 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CEH16358.1 - 0.18 12.3 0.0 0.59 10.6 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease RVT_2 PF07727.9 CEH16360.1 - 2.3e-70 236.3 0.0 3.3e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEH16360.1 - 1.6e-21 76.6 0.0 1.1e-20 73.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 CEH16360.1 - 1.5e-10 40.6 0.0 3.3e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CEH16360.1 - 3.7e-10 39.6 0.3 7e-10 38.7 0.2 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CEH16360.1 - 5.5e-07 29.1 0.0 1.4e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 CEH16360.1 - 0.0027 17.5 5.3 0.0062 16.4 3.6 1.7 1 0 0 1 1 1 1 Zinc knuckle rve_3 PF13683.1 CEH16360.1 - 0.0068 15.9 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain UBN2_3 PF14244.1 CEH16360.1 - 0.048 13.2 0.2 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 CEH16360.1 - 0.18 11.4 1.9 0.44 10.2 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 CEH16361.1 - 7.5e-68 228.4 0.0 1.1e-67 227.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH16361.1 - 8.7e-30 103.6 0.1 1.5e-28 99.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH16361.1 - 1.3e-08 34.2 0.7 5.9e-06 25.4 0.0 3.0 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 CEH16361.1 - 0.017 14.2 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEH16361.1 - 0.074 12.7 0.0 0.6 9.7 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Abhydrolase_3 PF07859.8 CEH16363.1 - 8e-33 113.7 0.1 5.8e-23 81.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_31 PF13847.1 CEH16364.1 - 3.7e-14 52.5 0.1 5.5e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH16364.1 - 5.3e-12 46.3 0.0 1.6e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CEH16364.1 - 4.9e-11 42.2 0.1 6.8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 CEH16364.1 - 6.5e-10 38.9 0.0 2.4e-09 37.1 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH16364.1 - 5.6e-08 33.1 0.0 1.4e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH16364.1 - 3.2e-07 30.3 0.0 6.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CEH16364.1 - 3.2e-07 29.7 0.0 4.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CEH16364.1 - 3e-06 27.6 0.0 6.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEH16364.1 - 5e-06 26.0 0.3 1.1e-05 24.9 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.11 CEH16364.1 - 7.7e-06 25.0 0.0 1.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 CEH16364.1 - 1.8e-05 23.6 0.0 2.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 CEH16364.1 - 1.9e-05 24.9 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CEH16364.1 - 3.7e-05 23.3 0.1 5.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 CEH16364.1 - 0.00073 19.5 0.3 0.0011 18.9 0.2 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 CEH16364.1 - 0.001 18.2 0.1 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 CEH16364.1 - 0.0015 19.3 0.0 0.0036 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 CEH16364.1 - 0.0042 16.5 0.2 0.0062 16.0 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 CEH16364.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 CEH16364.1 - 0.032 13.6 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.1 CEH16364.1 - 0.033 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 CEH16364.1 - 0.11 11.6 0.5 0.42 9.7 0.3 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB Tctex-1 PF03645.8 CEH16365.1 - 0.0071 16.1 0.5 0.2 11.5 0.3 2.2 1 1 0 1 1 1 1 Tctex-1 family Methyltransf_16 PF10294.4 CEH16366.1 - 3.1e-41 140.7 0.0 4e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CEH16366.1 - 6.6e-05 23.4 0.0 0.0001 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEH16366.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CEH16366.1 - 0.03 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Apt1 PF10351.4 CEH16367.1 - 3.5 6.3 8.9 3.8 6.2 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Aminotran_1_2 PF00155.16 CEH16370.1 - 3.1e-57 194.1 0.0 9.7e-57 192.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CEH16370.1 - 0.0038 16.3 0.0 0.0061 15.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CEH16370.1 - 0.015 13.6 0.0 0.072 11.3 0.0 1.9 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HEAT PF02985.17 CEH16371.1 - 1.3e-06 27.9 0.2 0.22 11.6 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat Pkinase PF00069.20 CEH16371.1 - 1.5e-05 24.2 0.0 2.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.1 CEH16371.1 - 0.0019 18.6 1.4 2.9 8.5 0.1 4.1 2 1 2 4 4 4 1 HEAT-like repeat Pkinase_Tyr PF07714.12 CEH16371.1 - 0.0058 15.7 0.0 0.0093 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CLASP_N PF12348.3 CEH16371.1 - 0.0091 15.3 0.0 0.059 12.7 0.0 2.1 1 1 1 2 2 2 1 CLASP N terminal Kinase-like PF14531.1 CEH16371.1 - 0.02 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Cohesin_HEAT PF12765.2 CEH16371.1 - 0.05 13.5 0.3 5.4 7.0 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.2 CEH16371.1 - 0.14 12.5 0.0 7.1 7.0 0.0 2.7 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region UPF0113 PF03657.8 CEH16372.1 - 2e-07 30.8 0.0 2.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) DUF4516 PF14990.1 CEH16372.1 - 0.089 12.3 0.5 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) Pribosyltran_N PF13793.1 CEH16373.1 - 1.1e-41 141.1 0.2 4.7e-41 139.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CEH16373.1 - 3.2e-37 128.0 0.6 1.1e-30 106.7 0.2 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CEH16373.1 - 9.1e-15 54.4 0.6 3.9e-08 33.0 0.1 3.1 3 0 0 3 3 3 2 Phosphoribosyl transferase domain UPRTase PF14681.1 CEH16373.1 - 0.0027 16.9 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BRO1 PF03097.13 CEH16374.1 - 2.2e-21 76.0 0.0 3.5e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain TPR_10 PF13374.1 CEH16374.1 - 0.077 12.9 1.2 11 6.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat IMS PF00817.15 CEH16375.1 - 1.5e-42 144.8 0.2 3e-42 143.9 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CEH16375.1 - 2.1e-14 53.5 0.6 5.9e-14 52.0 0.4 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CEH16375.1 - 2.5e-06 27.2 0.0 5.8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif VPS28 PF03997.7 CEH16375.1 - 0.071 12.7 0.7 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 VPS28 protein UIM PF02809.15 CEH16375.1 - 1.9 8.2 9.5 0.42 10.3 2.4 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif tRNA-synt_2b PF00587.20 CEH16376.1 - 1.1e-40 139.0 0.0 2.1e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEH16376.1 - 7.9e-07 28.9 0.0 2.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.1 CEH16376.1 - 0.0029 16.7 0.0 0.0084 15.1 0.0 1.8 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Syntaxin-18_N PF10496.4 CEH16377.1 - 2.7e-09 36.7 0.1 1.9e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 CEH16377.1 - 0.00043 19.9 4.7 0.00069 19.2 1.7 2.4 2 0 0 2 2 2 1 SNARE domain RNase_PH PF01138.16 CEH16378.1 - 2e-26 92.8 0.2 3.2e-26 92.1 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNA_pol_Rpc34 PF05158.7 CEH16379.1 - 1.7e-73 247.6 0.1 3.8e-61 207.0 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit TrmB PF01978.14 CEH16379.1 - 0.001 18.7 0.2 1.6 8.5 0.0 2.6 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 CEH16379.1 - 0.0039 16.8 0.1 0.0092 15.6 0.1 1.6 1 0 0 1 1 1 1 MarR family HxlR PF01638.12 CEH16379.1 - 0.032 13.8 0.1 0.06 12.9 0.1 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix LT-IIB PF06453.6 CEH16379.1 - 0.074 12.7 0.0 0.73 9.5 0.0 2.1 2 0 0 2 2 2 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) F-box-like PF12937.2 CEH16381.1 - 0.00032 20.3 0.1 0.0013 18.4 0.1 2.0 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 CEH16381.1 - 0.19 11.3 0.3 13 5.5 0.0 3.6 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) Sec1 PF00995.18 CEH16382.1 - 7.8e-119 397.8 0.0 9.1e-119 397.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Velvet PF11754.3 CEH16382.1 - 0.045 13.3 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 Velvet factor IU_nuc_hydro PF01156.14 CEH16383.1 - 8.2e-49 166.5 0.0 1.3e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LEA_2 PF03168.8 CEH16385.1 - 5.3e-06 26.7 0.2 1.4e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Late embryogenesis abundant protein Arrestin_C PF02752.17 CEH16385.1 - 0.0039 17.3 0.1 0.0066 16.5 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Sigma54_DBD PF04552.8 CEH16385.1 - 0.087 12.3 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54, DNA binding domain MecA_N PF05223.6 CEH16385.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain DUF2207 PF09972.4 CEH16385.1 - 2.9 6.3 4.7 0.95 7.9 0.4 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) VPS28 PF03997.7 CEH16386.1 - 3.8e-50 170.1 0.0 1.7e-37 128.8 0.0 2.0 2 0 0 2 2 2 2 VPS28 protein FAD_binding_1 PF00667.15 CEH16387.1 - 1.3e-56 191.5 0.0 2.9e-56 190.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CEH16387.1 - 1.6e-33 115.7 0.4 4.1e-33 114.3 0.3 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CEH16387.1 - 2.4e-22 79.5 0.1 1.2e-21 77.3 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 CEH16387.1 - 0.03 14.3 0.0 0.075 13.0 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain Glyco_hydro_20 PF00728.17 CEH16388.1 - 8.1e-29 100.8 0.1 1.3e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Fungal_trans PF04082.13 CEH16389.1 - 1.4e-30 106.0 0.0 3e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SIR2 PF02146.12 CEH16390.1 - 1.9e-53 180.8 0.0 3.2e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 CEH16390.1 - 1.7e-06 27.7 0.7 0.00065 19.2 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF592) DUF778 PF05608.7 CEH16390.1 - 0.017 15.0 0.5 0.12 12.3 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF778) TPP_enzyme_M PF00205.17 CEH16390.1 - 0.043 13.5 0.2 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zf-ribbon_3 PF13248.1 CEH16390.1 - 0.088 12.0 0.3 0.23 10.7 0.2 1.8 1 0 0 1 1 1 0 zinc-ribbon domain TRAPP PF04051.11 CEH16391.1 - 9e-21 73.9 0.1 3.7e-14 52.5 0.0 2.3 1 1 1 2 2 2 2 Transport protein particle (TRAPP) component eIF-6 PF01912.13 CEH16392.1 - 6.5e-83 276.6 0.5 8.9e-83 276.2 0.4 1.2 1 0 0 1 1 1 1 eIF-6 family Abhydrolase_6 PF12697.2 CEH16393.1 - 4.1e-24 85.7 0.3 1.3e-23 84.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Glyco_transf_8 PF01501.15 CEH16393.1 - 1.7e-20 73.4 0.0 1.9e-19 69.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Abhydrolase_5 PF12695.2 CEH16393.1 - 2.1e-20 72.9 0.0 4.7e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CEH16393.1 - 3.8e-14 52.2 0.0 1.3e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CEH16393.1 - 0.00018 20.7 0.1 0.00077 18.7 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 CEH16393.1 - 0.0017 17.8 0.0 0.0049 16.3 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 CEH16393.1 - 0.0021 17.6 0.0 0.09 12.3 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 CEH16393.1 - 0.0039 16.4 0.0 0.36 10.0 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 CEH16393.1 - 0.0083 15.7 0.0 0.025 14.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CEH16393.1 - 0.028 13.7 0.0 0.073 12.4 0.0 1.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Mannosyl_trans3 PF11051.3 CEH16393.1 - 0.042 13.1 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Abhydrolase_2 PF02230.11 CEH16393.1 - 0.057 12.8 0.1 1.8 7.9 0.0 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 CEH16393.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Tannase PF07519.6 CEH16393.1 - 0.18 10.4 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase RRM_1 PF00076.17 CEH16394.1 - 7.6e-58 192.0 0.0 2.2e-18 65.6 0.0 7.8 8 0 0 8 8 8 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH16394.1 - 1.7e-43 146.4 0.0 3.6e-13 49.2 0.0 6.6 6 0 0 6 6 6 6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH16394.1 - 2.3e-15 56.1 0.0 0.00034 20.4 0.0 6.4 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEH16394.1 - 0.063 13.0 0.0 4.7 7.0 0.0 3.1 3 1 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRN3 PF05327.6 CEH16394.1 - 0.2 9.7 3.7 0.068 11.2 0.4 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 AhpC-TSA PF00578.16 CEH16395.1 - 1.7e-30 105.2 0.0 2.3e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CEH16395.1 - 2.9e-12 46.3 0.0 4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CEH16395.1 - 3.5e-09 36.1 0.0 6.7e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Herpes_V23 PF01802.12 CEH16395.1 - 0.015 14.3 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein DUF2375 PF09558.5 CEH16395.1 - 0.031 14.1 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) Latarcin PF10279.4 CEH16396.1 - 0.0028 17.8 1.3 0.0068 16.5 0.9 1.6 1 0 0 1 1 1 1 Latarcin precursor DUF4131 PF13567.1 CEH16396.1 - 0.011 15.1 0.4 0.033 13.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MCM PF00493.18 CEH16397.1 - 8e-136 452.1 0.7 8e-136 452.1 0.5 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 CEH16397.1 - 8.4e-19 68.2 0.0 2.6e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CEH16397.1 - 7.4e-08 31.8 0.0 1.1e-06 27.9 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CEH16397.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CEH16397.1 - 0.0033 16.8 0.0 0.0066 15.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 CEH16397.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) His_Phos_2 PF00328.17 CEH16398.1 - 1.3e-70 238.5 0.1 1.8e-70 238.0 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CEH16398.1 - 4.3e-06 26.3 0.0 7.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CEH16398.1 - 0.14 12.0 0.1 0.4 10.5 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain Proteasome PF00227.21 CEH16399.1 - 7.8e-24 84.0 0.0 9.6e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit TRP PF06011.7 CEH16400.1 - 1.6e-76 257.6 2.2 2.1e-76 257.2 1.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CEH16400.1 - 8.8e-32 110.0 0.0 1.5e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 ML-like domain HemY_N PF07219.8 CEH16400.1 - 1.7 8.2 6.0 1.6 8.3 0.6 3.1 3 0 0 3 3 3 0 HemY protein N-terminus PCI_Csn8 PF10075.4 CEH16402.1 - 5.8e-34 116.9 0.0 7.6e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CEH16402.1 - 7e-30 104.1 0.0 9.1e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2227 PF09988.4 CEH16402.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) Proteasome PF00227.21 CEH16403.1 - 1.1e-58 197.6 0.0 1.7e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CEH16403.1 - 3.2e-13 48.7 0.1 5.3e-13 48.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3536 PF12055.3 CEH16403.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) FtsZ_C PF12327.3 CEH16403.1 - 0.073 13.1 0.5 0.16 12.0 0.4 1.5 1 0 0 1 1 1 0 FtsZ family, C-terminal domain Asp PF00026.18 CEH16404.1 - 3.4e-42 144.7 0.1 3e-29 102.2 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease AAA_18 PF13238.1 CEH16406.1 - 1.1e-24 87.1 0.4 1.7e-24 86.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEH16406.1 - 1.9e-09 38.3 0.7 3.3e-09 37.6 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEH16406.1 - 0.00025 20.9 0.0 0.029 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CEH16406.1 - 0.00048 20.1 0.1 0.0019 18.2 0.0 2.1 2 1 1 3 3 3 1 AAA domain KTI12 PF08433.5 CEH16406.1 - 0.00082 18.6 0.0 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 CEH16406.1 - 0.0021 17.2 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 CEH16406.1 - 0.0024 17.9 0.0 0.0066 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 CEH16406.1 - 0.0028 17.0 0.1 0.49 9.7 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_16 PF13191.1 CEH16406.1 - 0.0063 16.5 0.0 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain SKI PF01202.17 CEH16406.1 - 0.0066 16.3 0.0 0.07 12.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase NTPase_1 PF03266.10 CEH16406.1 - 0.0086 15.7 0.5 0.034 13.8 0.0 2.1 2 0 0 2 2 2 1 NTPase DAP3 PF10236.4 CEH16406.1 - 0.037 12.9 0.7 0.075 11.9 0.0 1.7 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.17 CEH16406.1 - 0.042 14.0 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 CEH16406.1 - 0.044 13.5 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CEH16406.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CEH16406.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain ADK PF00406.17 CEH16406.1 - 0.059 13.2 0.1 8.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase ArgK PF03308.11 CEH16406.1 - 0.061 12.0 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 CEH16406.1 - 0.063 12.6 0.1 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CEH16406.1 - 0.08 12.7 0.3 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 CEH16406.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.4 2 0 0 2 2 2 0 AAA-like domain Put_Phosphatase PF06888.7 CEH16407.1 - 4.5e-49 166.7 0.0 5.1e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 CEH16407.1 - 0.053 13.7 0.0 0.19 11.9 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AP_endonuc_2 PF01261.19 CEH16408.1 - 1.3e-24 86.6 0.8 2.1e-24 85.9 0.1 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel AMH_N PF04709.7 CEH16409.1 - 0.078 11.9 0.7 0.076 11.9 0.5 1.1 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region Tmemb_cc2 PF10267.4 CEH16411.1 - 0.11 11.0 1.5 0.15 10.6 1.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ras PF00071.17 CEH16412.1 - 7.1e-45 152.2 0.0 2.6e-42 143.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CEH16412.1 - 5.8e-23 81.6 0.1 1.2e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH16412.1 - 4.3e-12 45.6 0.0 7.4e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEH16412.1 - 1.5e-05 24.2 0.0 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CEH16412.1 - 9.1e-05 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CEH16412.1 - 0.00031 20.0 0.1 0.00051 19.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CEH16412.1 - 0.0053 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 CEH16412.1 - 0.07 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CEH16412.1 - 0.73 8.9 2.5 1.4 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RhoGEF PF00621.15 CEH16413.1 - 3.5e-19 69.3 0.0 4.9e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain DUF4322 PF14210.1 CEH16413.1 - 0.17 11.4 0.2 0.32 10.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) RNase_H PF00075.19 CEH16414.1 - 1.6e-26 93.1 0.2 3.4e-26 92.1 0.0 1.6 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.11 CEH16414.1 - 2.1e-16 59.6 0.7 5.2e-16 58.3 0.5 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.1 CEH16414.1 - 0.0053 16.4 0.2 0.12 12.2 0.0 2.6 3 0 0 3 3 3 1 Reverse transcriptase-like Actin PF00022.14 CEH16417.1 - 3.7e-39 134.2 0.0 5.7e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CEH16417.1 - 0.01 14.4 0.0 0.041 12.4 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein GAGA_bind PF06217.7 CEH16420.1 - 5.9e-05 23.1 10.2 0.00011 22.2 2.5 4.5 2 2 2 4 4 4 3 GAGA binding protein-like family OTU PF02338.14 CEH16421.1 - 0.012 16.2 0.0 0.022 15.3 0.0 1.5 1 0 0 1 1 1 0 OTU-like cysteine protease Utp14 PF04615.8 CEH16422.1 - 3.8e-25 88.1 0.1 4.6e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Utp14 protein Utp14 PF04615.8 CEH16423.1 - 1.4e-90 304.5 27.6 3.3e-67 227.2 2.8 2.0 1 1 1 2 2 2 2 Utp14 protein Ribonuc_red_lgC PF02867.10 CEH16424.1 - 3.2e-214 712.4 0.0 4.2e-214 712.0 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CEH16424.1 - 8.7e-25 86.3 0.0 2.1e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CEH16424.1 - 2.9e-16 59.6 0.3 9.2e-16 58.0 0.1 2.1 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 CEH16424.1 - 0.036 12.1 0.0 0.06 11.4 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase G-gamma PF00631.17 CEH16424.1 - 0.14 11.9 0.1 13 5.6 0.0 2.6 2 0 0 2 2 2 0 GGL domain GMC_oxred_N PF00732.14 CEH16425.1 - 7.5e-60 202.5 0.0 1e-59 202.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CEH16425.1 - 6.5e-30 104.3 0.1 1.7e-29 103.0 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CEH16425.1 - 1.3e-05 24.2 1.6 0.00022 20.2 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 CEH16425.1 - 0.00025 20.9 0.4 0.00075 19.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEH16425.1 - 0.001 18.0 6.1 0.0013 17.7 2.8 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CEH16425.1 - 0.0024 17.7 0.3 0.018 14.9 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CEH16425.1 - 0.0026 16.8 0.3 0.016 14.3 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 CEH16425.1 - 0.0034 17.4 1.4 0.51 10.3 1.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEH16425.1 - 0.0096 14.8 0.3 0.015 14.2 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 CEH16425.1 - 0.022 13.8 0.9 0.022 13.8 0.6 1.9 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.9 CEH16425.1 - 0.054 11.9 0.5 0.094 11.1 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 CEH16425.1 - 0.058 13.1 0.4 0.16 11.7 0.2 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 CEH16425.1 - 0.059 13.7 0.9 0.14 12.6 0.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CEH16425.1 - 0.098 12.6 0.3 0.31 11.0 0.1 1.9 2 0 0 2 2 1 0 TrkA-N domain Srg PF02118.16 CEH16426.1 - 0.055 12.8 0.4 0.087 12.2 0.3 1.2 1 0 0 1 1 1 0 Srg family chemoreceptor ketoacyl-synt PF00109.21 CEH16427.1 - 4.4e-59 200.0 3.1 5.5e-59 199.7 0.9 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CEH16427.1 - 3.4e-33 113.9 0.1 9.6e-33 112.5 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 CEH16427.1 - 2.9e-29 102.1 0.0 5.3e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 CEH16427.1 - 1.9e-26 93.1 0.6 7.1e-14 51.8 0.2 2.4 1 1 1 2 2 2 2 Acyl transferase domain KR PF08659.5 CEH16427.1 - 7.9e-12 45.2 0.0 2.1e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.7 CEH16427.1 - 9.1e-11 42.1 0.0 2.1e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 CEH16427.1 - 2.1e-10 40.7 0.0 7.3e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.1 CEH16427.1 - 9.9e-10 38.3 0.0 3.4e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 CEH16427.1 - 8.8e-08 32.3 0.1 3e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 CEH16427.1 - 6.4e-06 25.8 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.5 CEH16427.1 - 4.6e-05 22.9 0.9 0.00022 20.7 0.7 2.3 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 CEH16427.1 - 0.00083 18.4 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF938 PF06080.7 CEH16427.1 - 0.0015 18.1 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_11 PF08241.7 CEH16427.1 - 0.0037 17.7 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH16427.1 - 0.012 16.1 0.0 0.083 13.4 0.0 2.4 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 CEH16427.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 CEH16427.1 - 0.2 11.0 0.0 0.47 9.8 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 CEH16427.1 - 0.4 9.6 0.0 0.93 8.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GMC_oxred_C PF05199.8 CEH16428.1 - 1.3e-30 106.6 0.0 2.8e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CEH16428.1 - 1.3e-19 70.4 0.0 1.9e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase NmrA PF05368.8 CEH16429.1 - 2.1e-19 69.7 0.0 4.9e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 CEH16429.1 - 5.8e-09 36.2 0.2 1.4e-08 34.9 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CEH16429.1 - 0.0013 19.0 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CEH16429.1 - 0.0033 16.4 0.1 0.0046 15.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 CEH16429.1 - 0.0081 14.8 0.0 0.014 14.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CEH16429.1 - 0.019 14.4 0.1 0.04 13.3 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CEH16429.1 - 0.038 12.9 0.2 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein SbcCD_C PF13558.1 CEH16430.1 - 5.2e-10 39.1 0.0 1.9e-09 37.3 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 CEH16430.1 - 7.2e-07 29.4 0.3 7.2e-07 29.4 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 CEH16430.1 - 0.013 13.9 0.2 0.013 13.9 0.1 6.2 1 1 5 7 7 7 0 AAA domain Mit_KHE1 PF10173.4 CEH16433.1 - 4.4e-12 46.2 0.0 4.7e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF4660 PF15559.1 CEH16433.1 - 0.06 13.4 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) Gag_p12 PF01141.13 CEH16433.1 - 0.11 12.5 0.8 4.7 7.4 0.0 2.3 2 1 0 2 2 2 0 Gag polyprotein, inner coat protein p12 C2 PF00168.25 CEH16435.1 - 8.5e-13 47.9 0.0 1.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Malic_M PF03949.10 CEH16436.1 - 6.8e-84 281.4 0.0 9e-84 281.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CEH16436.1 - 3.2e-65 219.1 0.0 5.9e-65 218.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain CoatB PF10389.4 CEH16437.1 - 0.36 10.7 3.0 0.63 9.9 0.8 2.2 2 0 0 2 2 2 0 Bacteriophage coat protein B Sdh_cyt PF01127.17 CEH16438.1 - 5.1e-23 81.1 1.6 6.3e-23 80.9 1.1 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NPL4 PF05021.10 CEH16439.1 - 1.7e-96 322.9 0.0 2.4e-96 322.5 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CEH16439.1 - 0.00029 20.5 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region zf-RanBP PF00641.13 CEH16439.1 - 0.089 11.9 1.2 0.18 10.9 0.9 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others FAD_binding_7 PF03441.9 CEH16440.1 - 2.2e-88 296.0 0.1 3.5e-88 295.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CEH16440.1 - 1.4e-31 109.4 0.0 2.5e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase HECT PF00632.20 CEH16441.1 - 3.9e-71 239.8 0.0 5.6e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 CEH16441.1 - 0.0037 16.7 1.3 0.0037 16.7 0.9 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF1101 PF06503.6 CEH16441.1 - 0.29 9.9 0.1 0.47 9.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) Toxin_63 PF15541.1 CEH16443.1 - 0.00041 20.2 0.0 0.00058 19.7 0.0 1.2 1 0 0 1 1 1 1 Putative toxin 63 eIF3_N PF09440.5 CEH16444.1 - 1.6e-38 131.9 5.0 1.6e-38 131.9 3.4 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 CEH16444.1 - 1.6e-10 41.2 0.1 3.1e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 PCI domain DUF3321 PF11968.3 CEH16445.1 - 9.6e-29 100.5 0.8 2.2e-14 53.6 0.0 2.4 3 0 0 3 3 3 2 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 CEH16445.1 - 0.00014 21.6 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH16445.1 - 0.071 13.5 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CEH16445.1 - 0.081 13.4 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TFIIA PF03153.8 CEH16445.1 - 0.4 10.5 8.1 0.54 10.0 5.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2217 PF10265.4 CEH16445.1 - 1.7 7.3 8.2 2.4 6.8 5.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Pkinase PF00069.20 CEH16446.1 - 1.2e-15 57.3 0.0 1.7e-14 53.6 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH16446.1 - 1.1e-12 47.6 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH16446.1 - 2.2e-06 27.5 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CEH16446.1 - 0.0014 17.9 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CEH16446.1 - 0.014 14.4 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CEH16446.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-HC2 PF13490.1 CEH16447.1 - 0.9 9.5 2.5 2.1 8.3 0.4 2.2 2 0 0 2 2 2 0 Putative zinc-finger Homeobox PF00046.24 CEH16448.1 - 6.5e-08 32.0 0.3 1.5e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEH16448.1 - 0.00041 19.9 0.2 0.0009 18.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Colicin_C PF12106.3 CEH16448.1 - 4.5 6.9 5.9 0.63 9.6 0.2 2.5 4 0 0 4 4 4 0 Colicin C terminal ribonuclease domain HTH_10 PF04967.7 CEH16449.1 - 0.013 15.0 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain HTH_psq PF05225.11 CEH16449.1 - 0.025 14.1 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_Tnp_1_2 PF13022.1 CEH16449.1 - 0.34 10.7 2.6 0.36 10.5 0.2 2.0 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase SHNi-TPR PF10516.4 CEH16453.1 - 6.9e-12 44.4 2.3 3.6e-11 42.1 0.2 3.1 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.1 CEH16453.1 - 2.7e-06 27.2 9.3 0.0003 20.6 1.6 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CEH16453.1 - 0.002 17.7 8.1 0.0026 17.3 1.1 2.7 2 0 0 2 2 2 1 TPR repeat DUF3543 PF12063.3 CEH16453.1 - 0.0027 16.9 0.0 0.13 11.4 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF3543) AATF-Che1 PF13339.1 CEH16453.1 - 1.6 8.8 10.2 11 6.1 0.1 3.6 3 1 0 3 3 3 0 Apoptosis antagonizing transcription factor Acyltransferase PF01553.16 CEH16455.1 - 6.3e-15 54.7 0.0 1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase CTK3 PF12243.3 CEH16458.1 - 2.8e-21 75.6 0.1 3.4e-20 72.1 0.0 2.4 1 1 1 2 2 2 1 CTD kinase subunit gamma CTK3 RNA_pol_Rpb5_C PF01191.14 CEH16459.1 - 2.8e-33 113.3 0.1 5.1e-33 112.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CEH16459.1 - 4.1e-17 62.3 0.6 8.6e-17 61.3 0.1 1.8 2 1 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 CEH16459.1 - 0.0081 15.9 0.1 0.026 14.3 0.0 1.7 1 1 1 2 2 2 1 Restriction endonuclease p450 PF00067.17 CEH16460.1 - 9.5e-45 152.9 0.8 1.2e-17 63.6 0.1 3.0 1 1 2 3 3 3 3 Cytochrome P450 CKAP2_C PF15297.1 CEH16460.1 - 0.016 14.0 0.1 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus NUDIX PF00293.23 CEH16461.1 - 1.3e-12 47.5 0.0 2.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF515 PF04415.7 CEH16461.1 - 3.3 5.8 7.4 6.4 4.8 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF1992 PF09350.5 CEH16462.1 - 4.2e-19 68.1 0.1 7.4e-18 64.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Solute_trans_a PF03619.11 CEH16464.1 - 4.4e-78 262.3 27.5 5.5e-78 262.0 19.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3605 PF12239.3 CEH16465.1 - 2.7e-19 69.5 0.2 8.9e-14 51.6 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3605) DEAD PF00270.24 CEH16466.1 - 1.3e-25 89.8 0.0 2.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 CEH16466.1 - 1.1e-13 51.5 1.4 4.2e-13 49.6 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 CEH16466.1 - 2.6e-11 43.2 0.0 7.5e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 CEH16466.1 - 0.00047 20.1 0.0 0.00097 19.1 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like WW PF00397.21 CEH16467.1 - 1.1e-06 28.3 5.9 1.8e-06 27.6 3.6 1.7 2 0 0 2 2 2 1 WW domain PCI PF01399.22 CEH16468.1 - 2e-09 37.7 0.0 1.4e-08 35.0 0.0 2.3 2 0 0 2 2 2 1 PCI domain Ribosomal_L6e PF01159.14 CEH16469.1 - 3.6e-32 110.8 0.0 6e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e RNA_pol_I_A49 PF06870.7 CEH16470.1 - 1e-69 235.0 0.0 1.6e-69 234.3 0.0 1.3 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Auxin_inducible PF02519.9 CEH16470.1 - 0.12 12.4 0.7 0.39 10.7 0.5 1.9 1 0 0 1 1 1 0 Auxin responsive protein DUF2462 PF09495.5 CEH16471.1 - 3.2e-14 53.4 9.6 3.2e-14 53.4 6.6 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) DUF3224 PF11528.3 CEH16471.1 - 0.091 12.2 0.1 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) NUDE_C PF04880.8 CEH16471.1 - 0.7 10.2 4.6 0.84 9.9 3.2 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF2188 PF09954.4 CEH16471.1 - 1.2 9.0 3.9 0.43 10.5 0.3 1.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) STE PF02200.11 CEH16474.1 - 8.8e-07 29.0 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor Nop25 PF09805.4 CEH16475.1 - 1.2e-19 70.7 19.5 1.2e-19 70.7 13.5 2.6 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) Ribosomal_S7 PF00177.16 CEH16476.1 - 1.1e-31 109.4 0.8 1.5e-31 108.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Xpo1 PF08389.7 CEH16479.1 - 2.4e-16 59.9 0.0 1.7e-15 57.2 0.0 2.6 1 0 0 1 1 1 1 Exportin 1-like protein HEAT_2 PF13646.1 CEH16479.1 - 0.13 12.5 4.8 2.3 8.5 0.0 5.0 6 0 0 6 6 6 0 HEAT repeats HEAT PF02985.17 CEH16479.1 - 0.5 10.5 0.0 0.5 10.5 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat PIG-X PF08320.7 CEH16483.1 - 0.0018 17.5 0.0 0.016 14.5 0.0 2.4 2 1 0 2 2 2 1 PIG-X / PBN1 ThiF PF00899.16 CEH16484.1 - 1.2e-10 41.3 0.0 2.2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family zf-DHHC PF01529.15 CEH16485.1 - 1.5e-43 148.1 2.8 4.9e-43 146.5 0.0 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 CEH16485.1 - 0.38 10.6 6.4 0.81 9.5 4.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon 2OG-FeII_Oxy_2 PF13532.1 CEH16487.1 - 4e-16 59.4 1.2 1.9e-13 50.6 0.0 3.1 2 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily GLE1 PF07817.8 CEH16489.1 - 2.2e-52 177.5 0.4 4.6e-52 176.5 0.0 1.7 2 0 0 2 2 2 1 GLE1-like protein DUF966 PF06136.8 CEH16489.1 - 5.5 6.3 13.7 8.2 5.7 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Elongin_A PF06881.6 CEH16490.1 - 1.5e-07 31.7 0.1 5.3e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CytoC_RC PF02276.13 CEH16490.1 - 0.058 12.4 0.0 0.06 12.4 0.0 1.0 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Herpes_UL3 PF03369.8 CEH16490.1 - 0.14 12.1 0.4 0.21 11.5 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL3 protein DNA_pol_viral_N PF00242.12 CEH16491.1 - 0.75 8.7 7.2 0.74 8.7 5.0 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Amino_oxidase PF01593.19 CEH16492.1 - 6.7e-29 101.2 1.5 1.9e-14 53.6 0.0 3.1 2 1 1 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CEH16492.1 - 9.2e-13 48.0 0.1 2.6e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CEH16492.1 - 0.0091 14.5 0.1 0.013 14.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 CEH16492.1 - 0.054 12.5 0.2 0.09 11.8 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 CEH16492.1 - 0.062 13.3 0.2 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEH16492.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 CEH16493.1 - 5.7e-21 74.6 42.4 1.5e-14 53.4 20.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_Tnp_Tc5 PF03221.11 CEH16494.1 - 6.9e-10 38.6 0.1 2.1e-09 37.0 0.1 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Crp_2 PF13545.1 CEH16494.1 - 0.01 15.5 0.1 1.2 8.9 0.0 3.3 4 0 0 4 4 4 0 Crp-like helix-turn-helix domain CENP-B_N PF04218.8 CEH16494.1 - 0.023 14.0 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_4 PF13613.1 CEH16494.1 - 0.062 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Herpes_capsid PF06112.6 CEH16494.1 - 8.7 6.3 14.6 17 5.4 10.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CbtB PF09489.5 CEH16498.1 - 2 8.4 7.0 0.52 10.2 0.0 3.3 3 1 1 4 4 4 0 Probable cobalt transporter subunit (CbtB) Rhodanese PF00581.15 CEH16499.1 - 1.4e-17 64.0 0.0 2.2e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain OS-D PF03392.8 CEH16501.1 - 0.13 12.2 0.0 0.14 12.1 0.0 1.0 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Fungal_trans PF04082.13 CEH16502.1 - 5.4e-10 38.5 0.0 3.6e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain MRP-S28 PF10213.4 CEH16503.1 - 4.6e-27 94.6 0.0 7.1e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein adh_short PF00106.20 CEH16504.1 - 5.9e-30 104.3 0.8 8.3e-30 103.9 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH16504.1 - 2.3e-16 60.2 0.4 3.1e-16 59.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH16504.1 - 7.3e-09 35.5 0.4 1.2e-08 34.8 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CEH16504.1 - 9.4e-07 29.0 0.2 1.2e-05 25.3 0.1 2.2 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CEH16504.1 - 1.7e-06 27.6 0.7 9.6e-06 25.2 0.2 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CEH16504.1 - 0.022 13.6 0.1 0.07 12.0 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 CEH16505.1 - 4.8e-58 195.2 0.0 6.8e-58 194.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CEH16505.1 - 2.2e-16 59.5 0.0 2.8e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CEH16505.1 - 3.5e-08 33.4 0.0 1.1e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CEH16505.1 - 0.0021 18.4 0.0 0.0043 17.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 CEH16505.1 - 0.0052 16.1 0.0 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain adh_short PF00106.20 CEH16505.1 - 0.0081 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Ribosomal_L3 PF00297.17 CEH16506.1 - 1.5e-20 73.7 1.3 7.5e-20 71.4 0.9 1.9 1 1 0 1 1 1 1 Ribosomal protein L3 CMAS PF02353.15 CEH16507.1 - 5.4e-64 215.8 0.3 6.9e-64 215.5 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CEH16507.1 - 1.8e-13 50.5 0.0 3.2e-12 46.4 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH16507.1 - 4.1e-13 49.6 0.3 6.8e-11 42.5 0.0 3.0 3 1 1 4 4 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH16507.1 - 2.6e-08 34.1 0.2 1.5e-07 31.7 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH16507.1 - 3.3e-07 30.8 0.0 2.5e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 CEH16507.1 - 1.8e-06 27.4 0.0 3.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 CEH16507.1 - 1.9e-06 27.5 0.0 3.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH16507.1 - 1.9e-05 24.6 0.1 7.8e-05 22.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CEH16507.1 - 2.2e-05 23.9 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 CEH16507.1 - 2.6e-05 23.8 0.0 4.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 CEH16507.1 - 3.4e-05 24.2 0.0 9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CEH16507.1 - 0.0027 16.7 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 CEH16507.1 - 0.03 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 CEH16507.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF21 PF01595.15 CEH16508.1 - 2.3e-34 118.2 0.3 2.3e-34 118.2 0.2 2.1 3 0 0 3 3 3 1 Domain of unknown function DUF21 CBS PF00571.23 CEH16508.1 - 7.8e-07 28.7 0.4 0.0025 17.5 0.0 2.9 3 0 0 3 3 3 2 CBS domain DUF4012 PF13196.1 CEH16508.1 - 0.16 12.0 2.6 0.97 9.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4012) Laps PF10169.4 CEH16508.1 - 0.31 11.2 2.4 12 6.1 0.5 2.4 2 0 0 2 2 2 0 Learning-associated protein DUF2489 PF10675.4 CEH16509.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) DUF1681 PF07933.9 CEH16510.1 - 2.4e-52 176.6 0.0 2.8e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Gelsolin PF00626.17 CEH16510.1 - 0.15 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Gelsolin repeat DUF4229 PF14012.1 CEH16512.1 - 1 9.3 4.7 0.68 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) FA_hydroxylase PF04116.8 CEH16515.1 - 5.8e-15 55.6 8.6 5.8e-15 55.6 6.0 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.11 CEH16516.1 - 5.6e-27 94.3 44.4 2.1e-26 92.5 26.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF159 PF02586.9 CEH16517.1 - 3.6e-32 111.6 0.2 8.4e-32 110.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 Asp-B-Hydro_N PF05279.6 CEH16517.1 - 0.014 15.3 17.6 0.02 14.7 12.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PPR_3 PF13812.1 CEH16518.1 - 0.0041 17.2 0.0 6.4 7.3 0.0 4.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain TPR_14 PF13428.1 CEH16518.1 - 0.0073 16.8 6.1 54 4.8 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat HD_3 PF13023.1 CEH16519.1 - 3.7e-40 137.3 0.1 3.7e-40 137.3 0.1 1.9 2 0 0 2 2 2 1 HD domain HD PF01966.17 CEH16519.1 - 0.0084 16.1 0.4 0.021 14.8 0.3 1.6 1 0 0 1 1 1 1 HD domain Acetyltransf_1 PF00583.19 CEH16520.1 - 2.5e-11 43.4 0.1 2e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEH16520.1 - 1.2e-06 28.5 0.0 4.7e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CEH16520.1 - 0.0017 18.3 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEH16520.1 - 0.02 14.9 0.0 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEH16520.1 - 0.035 13.8 0.2 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_3 PF13302.1 CEH16520.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain KAAG1 PF15354.1 CEH16520.1 - 0.38 11.1 2.2 0.3 11.4 0.3 1.7 2 0 0 2 2 2 0 Kidney-associated antigen 1 Arf PF00025.16 CEH16521.1 - 1.3e-79 265.4 0.1 1.5e-79 265.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CEH16521.1 - 2e-14 53.2 0.0 2.4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CEH16521.1 - 3.2e-13 49.3 0.0 3.4e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CEH16521.1 - 2.9e-12 45.9 1.3 3.7e-09 35.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CEH16521.1 - 3.2e-11 42.8 0.0 3.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CEH16521.1 - 2.2e-09 37.8 0.0 3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CEH16521.1 - 5e-06 26.4 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEH16521.1 - 0.0052 16.2 0.1 0.042 13.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 CEH16521.1 - 0.0065 15.5 0.4 0.014 14.4 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CEH16521.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CEH16521.1 - 0.13 11.7 0.3 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EPL1 PF10513.4 CEH16522.1 - 3.6e-25 89.0 0.0 3.6e-25 89.0 0.0 3.9 3 1 0 3 3 3 1 Enhancer of polycomb-like MSP1_C PF07462.6 CEH16522.1 - 7.2 4.8 7.6 14 3.9 5.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus GMC_oxred_N PF00732.14 CEH16525.1 - 1.9e-54 184.8 0.0 2.6e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CEH16525.1 - 1e-36 126.3 0.0 1.7e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CEH16525.1 - 3.2e-05 22.9 3.3 0.002 17.1 1.4 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEH16525.1 - 0.00011 21.1 5.3 0.11 11.2 1.8 2.2 1 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 CEH16525.1 - 0.00055 19.8 0.1 0.0019 18.1 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH16525.1 - 0.00088 19.2 0.8 0.0022 17.9 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CEH16525.1 - 0.0048 15.8 0.6 0.0073 15.2 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HNH_2 PF13391.1 CEH16525.1 - 0.088 12.6 0.0 0.34 10.7 0.0 2.0 1 0 0 1 1 1 0 HNH endonuclease HI0933_like PF03486.9 CEH16525.1 - 0.23 9.8 0.6 0.47 8.8 0.4 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 CEH16525.1 - 0.27 11.6 1.0 2.3 8.6 0.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Miro PF08477.8 CEH16526.1 - 3e-37 127.7 0.0 3.4e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 CEH16526.1 - 3.4e-27 94.0 0.0 1.7e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.7 CEH16526.1 - 6.9e-27 92.5 0.3 2.2e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 CEH16526.1 - 1.2e-26 92.9 0.0 2.8e-17 62.5 0.0 2.2 2 0 0 2 2 2 2 Ras family EF-hand_7 PF13499.1 CEH16526.1 - 9.6e-10 38.4 0.2 0.0021 18.1 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CEH16526.1 - 2.3e-09 36.3 0.4 0.0013 18.4 0.0 2.8 3 0 0 3 3 2 2 EF-hand domain EF-hand_1 PF00036.27 CEH16526.1 - 1.4e-08 33.3 0.2 0.0094 15.1 0.0 3.0 3 0 0 3 3 3 2 EF hand MMR_HSR1 PF01926.18 CEH16526.1 - 1.1e-06 28.5 0.1 0.013 15.4 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_5 PF13202.1 CEH16526.1 - 2e-06 26.8 5.0 0.0038 16.4 0.1 2.8 3 0 0 3 3 2 2 EF hand AAA_22 PF13401.1 CEH16526.1 - 2.7e-06 27.5 0.0 0.079 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CEH16526.1 - 1.5e-05 25.0 0.3 0.26 11.2 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 CEH16526.1 - 1.7e-05 24.0 0.1 0.0077 15.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CEH16526.1 - 3e-05 23.9 0.1 0.041 13.6 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.1 CEH16526.1 - 4.7e-05 22.8 0.2 0.21 11.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran PF00005.22 CEH16526.1 - 7.4e-05 23.0 0.1 0.27 11.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter MobB PF03205.9 CEH16526.1 - 0.0001 22.0 0.2 0.39 10.4 0.1 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CEH16526.1 - 0.00013 21.7 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 NACHT domain Viral_helicase1 PF01443.13 CEH16526.1 - 0.00025 20.6 0.2 0.37 10.2 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CEH16526.1 - 0.0003 20.4 0.1 0.3 10.8 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CEH16526.1 - 0.00044 19.7 0.1 0.066 12.6 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family EF-hand_8 PF13833.1 CEH16526.1 - 0.0011 18.5 0.5 1.5 8.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair AAA_33 PF13671.1 CEH16526.1 - 0.0016 18.3 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CEH16526.1 - 0.0022 18.2 0.1 0.36 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CEH16526.1 - 0.0022 18.1 0.0 0.37 10.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 CEH16526.1 - 0.0027 17.1 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 CEH16526.1 - 0.0029 16.5 0.1 2 7.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_30 PF13604.1 CEH16526.1 - 0.0056 16.2 0.1 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 CEH16526.1 - 0.007 15.9 1.3 3.2 7.2 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 CEH16526.1 - 0.0081 15.7 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain DAP3 PF10236.4 CEH16526.1 - 0.0081 15.1 0.3 0.41 9.5 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.14 CEH16526.1 - 0.0084 15.5 0.2 4.3 6.7 0.0 2.8 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 CEH16526.1 - 0.011 15.6 0.1 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 CEH16526.1 - 0.012 14.8 0.0 2.7 7.1 0.0 3.2 3 1 0 3 3 2 0 ADP-ribosylation factor family SRPRB PF09439.5 CEH16526.1 - 0.014 14.6 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.13 CEH16526.1 - 0.016 14.2 0.0 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 Septin NB-ARC PF00931.17 CEH16526.1 - 0.018 13.9 0.1 2.4 6.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MCM PF00493.18 CEH16526.1 - 0.02 13.6 0.1 0.48 9.1 0.0 2.2 2 0 0 2 2 2 0 MCM2/3/5 family Zeta_toxin PF06414.7 CEH16526.1 - 0.022 13.8 0.0 6 5.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin VirE PF05272.6 CEH16526.1 - 0.023 14.1 0.0 0.74 9.2 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_10 PF12846.2 CEH16526.1 - 0.028 13.8 0.0 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.4 CEH16526.1 - 0.028 13.0 0.1 2.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.20 CEH16526.1 - 0.033 13.6 0.1 8.2 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SPARC_Ca_bdg PF10591.4 CEH16526.1 - 0.034 14.1 0.3 8.4 6.4 0.0 3.1 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region AIG1 PF04548.11 CEH16526.1 - 0.035 13.1 0.5 0.29 10.2 0.0 2.2 2 0 0 2 2 2 0 AIG1 family AAA PF00004.24 CEH16526.1 - 0.046 13.9 0.1 1 9.5 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEH16526.1 - 0.063 14.1 0.8 19 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 CEH16526.1 - 0.067 11.8 0.0 0.84 8.2 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein NTPase_1 PF03266.10 CEH16526.1 - 0.076 12.7 0.2 0.69 9.5 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 CEH16526.1 - 0.11 12.3 0.0 5.1 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CEH16526.1 - 0.12 12.1 0.1 14 5.2 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase EF-hand_10 PF14788.1 CEH16526.1 - 0.15 11.7 1.4 0.41 10.3 0.1 2.1 2 0 0 2 2 2 0 EF hand PduV-EutP PF10662.4 CEH16526.1 - 0.28 10.6 0.1 34 3.9 0.0 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 CEH16526.1 - 0.28 10.1 0.0 8.2 5.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 CEH16526.1 - 0.32 9.6 0.2 4.7 5.8 0.1 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Aldedh PF00171.17 CEH16527.1 - 1.1e-125 419.6 1.1 1.4e-125 419.2 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CEH16527.1 - 7.6e-07 28.1 0.1 1.9e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pox_TAA1 PF03295.9 CEH16527.1 - 0.009 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Poxvirus trans-activator protein A1 C-terminal eIF-5_eIF-2B PF01873.12 CEH16528.1 - 8.4e-46 154.6 0.2 1.2e-45 154.1 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-HYPF PF07503.7 CEH16528.1 - 0.042 13.2 0.5 3.2 7.2 0.1 2.5 2 0 0 2 2 2 0 HypF finger TF_Zn_Ribbon PF08271.7 CEH16528.1 - 0.075 12.3 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.5 CEH16528.1 - 0.37 10.9 3.5 3.8 7.7 0.0 2.4 1 1 1 2 2 2 0 Archaeal TRASH domain Elf1 PF05129.8 CEH16528.1 - 0.85 9.3 3.9 0.25 11.0 0.4 1.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like CK_II_beta PF01214.13 CEH16529.1 - 3.7e-79 264.5 0.0 5.1e-79 264.0 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Pho88 PF10032.4 CEH16531.1 - 6.5e-68 227.7 0.0 7.1e-68 227.6 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) SPC25 PF06703.6 CEH16531.1 - 0.11 12.0 0.3 0.19 11.3 0.2 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DER1 PF04511.10 CEH16532.1 - 1.1e-51 175.1 2.7 1.2e-51 174.9 1.9 1.0 1 0 0 1 1 1 1 Der1-like family DUF2955 PF11168.3 CEH16532.1 - 3.2 7.4 10.3 0.15 11.7 1.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2955) PRP3 PF08572.5 CEH16533.1 - 1.2e-64 217.7 0.4 1.9e-64 217.1 0.2 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CEH16533.1 - 8.5e-33 112.7 0.5 1.7e-32 111.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) M_domain PF12938.2 CEH16533.1 - 0.035 13.8 5.6 0.061 13.1 3.9 1.3 1 0 0 1 1 1 0 M domain of GW182 3HCDH_N PF02737.13 CEH16534.1 - 2.9e-52 176.9 3.3 4e-52 176.4 2.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CEH16534.1 - 6.6e-07 29.6 0.1 2.5e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 CEH16534.1 - 0.00023 20.9 2.1 0.00044 20.0 1.5 1.4 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 CEH16534.1 - 0.0039 16.5 1.9 0.018 14.4 1.3 2.0 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 CEH16534.1 - 0.0041 16.1 0.9 0.006 15.6 0.6 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 CEH16534.1 - 0.0074 16.1 5.0 0.054 13.3 2.9 2.5 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1188 PF06690.6 CEH16534.1 - 0.021 13.9 0.5 0.051 12.6 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1188) Pyr_redox PF00070.22 CEH16534.1 - 0.052 13.9 0.7 0.099 13.0 0.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CEH16534.1 - 0.07 12.7 1.1 0.12 11.9 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Arch_ATPase PF01637.13 CEH16534.1 - 0.076 12.7 0.7 0.19 11.3 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase D123 PF07065.9 CEH16534.1 - 0.083 11.9 0.1 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 D123 NAD_binding_8 PF13450.1 CEH16534.1 - 0.12 12.4 0.7 0.26 11.3 0.4 1.7 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEH16534.1 - 0.13 11.1 0.4 0.17 10.7 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Mannitol_dh PF01232.18 CEH16534.1 - 0.17 11.8 0.6 0.42 10.5 0.2 1.7 1 1 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain F420_oxidored PF03807.12 CEH16534.1 - 0.21 12.0 5.9 17 5.9 4.1 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 CEH16534.1 - 1.8 8.5 5.4 4.3 7.2 2.3 2.4 1 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_N PF08240.7 CEH16535.1 - 5.4e-27 93.7 1.6 5.4e-27 93.7 1.1 2.0 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEH16535.1 - 1.3e-13 50.5 0.1 2.3e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH16535.1 - 0.00087 20.1 0.1 0.0016 19.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Polysacc_deac_1 PF01522.16 CEH16537.1 - 2.9e-23 81.8 0.0 5.4e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEH16537.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DPBB_1 PF03330.13 CEH16538.1 - 2e-09 37.2 0.0 4.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SOG2 PF10428.4 CEH16538.1 - 0.00042 19.1 3.5 0.00042 19.1 2.4 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Menin PF05053.8 CEH16538.1 - 0.0017 16.6 0.6 0.0017 16.6 0.4 1.1 1 0 0 1 1 1 1 Menin Sporozoite_P67 PF05642.6 CEH16538.1 - 0.037 11.9 13.0 0.049 11.5 9.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.6 CEH16538.1 - 0.088 10.7 23.3 0.13 10.2 16.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ORC6 PF05460.8 CEH16538.1 - 0.25 10.3 8.2 0.3 10.1 5.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Macoilin PF09726.4 CEH16538.1 - 1.5 7.0 12.2 1.8 6.7 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 CEH16538.1 - 1.8 7.9 14.4 2.6 7.4 10.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Plasmodium_Vir PF05795.6 CEH16538.1 - 2.8 7.0 5.0 3.7 6.6 3.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Sec3_C PF09763.4 CEH16538.1 - 2.8 5.9 5.6 3.3 5.7 3.9 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 Mucin PF01456.12 CEH16538.1 - 3.6 7.3 33.3 0.16 11.7 18.9 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Golgin_A5 PF09787.4 CEH16538.1 - 5 5.5 14.0 6.8 5.0 9.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2413 PF10310.4 CEH16538.1 - 8.4 5.0 9.6 12 4.6 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TPR_MLP1_2 PF07926.7 CEH16539.1 - 3.5e-23 81.7 20.6 3.5e-23 81.7 14.3 17.0 4 3 9 13 13 13 5 TPR/MLP1/MLP2-like protein Na_H_Exchanger PF00999.16 CEH16540.1 - 9e-58 195.6 24.9 1.1e-57 195.3 17.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CAS_CSE1 PF03378.10 CEH16542.1 - 1.2e-121 406.0 0.0 5e-121 404.0 0.0 2.0 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 CEH16542.1 - 6.9e-117 390.1 0.0 1.8e-116 388.7 0.0 1.7 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.14 CEH16542.1 - 1.1e-09 38.0 0.0 2.9e-08 33.5 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CEH16542.1 - 0.00044 20.1 2.9 0.0095 15.8 0.0 4.5 5 1 1 6 6 6 1 Exportin 1-like protein DUF1981 PF09324.5 CEH16542.1 - 0.062 12.8 0.0 0.86 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Arm PF00514.18 CEH16542.1 - 2.1 8.3 4.8 16 5.5 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat WD40 PF00400.27 CEH16543.1 - 2.3e-30 103.3 15.0 9.3e-08 31.6 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat LMWPc PF01451.16 CEH16544.1 - 4.8e-34 117.6 0.0 5.7e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF2742 PF10888.3 CEH16544.1 - 0.012 15.4 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) RTC PF01137.16 CEH16547.1 - 5.6e-60 201.9 0.0 7.1e-60 201.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CEH16547.1 - 4.3e-27 94.1 0.0 7e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF1752 PF08550.5 CEH16548.1 - 2.7e-11 42.8 0.9 5e-11 41.9 0.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SAP30_Sin3_bdg PF13867.1 CEH16550.1 - 0.0045 16.8 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF3277 PF11681.3 CEH16550.1 - 0.074 12.5 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) WD40 PF00400.27 CEH16551.1 - 6.6e-08 32.1 1.5 0.0023 17.7 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CEH16551.1 - 0.04 13.6 0.1 2.8 7.5 0.0 2.9 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Thiolase_C PF02803.13 CEH16552.1 - 5.4e-10 38.7 1.6 2.1e-09 36.8 0.3 2.4 2 1 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 CEH16552.1 - 1.4e-09 37.3 1.4 1.2e-08 34.3 0.1 2.3 1 1 1 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 CEH16552.1 - 1.6e-05 24.5 2.9 0.00032 20.2 0.7 2.3 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CEH16552.1 - 0.0051 16.4 0.5 0.13 11.9 0.1 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 CEH16552.1 - 0.014 15.2 0.5 0.68 9.8 0.0 3.1 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.6 CEH16552.1 - 0.034 12.6 0.0 0.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Pkinase PF00069.20 CEH16553.1 - 1.6e-37 129.0 0.0 3.3e-37 128.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH16553.1 - 5.6e-16 58.3 0.0 1.1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH16553.1 - 0.0087 15.8 0.1 0.0087 15.8 0.1 3.3 4 0 0 4 4 4 1 Phosphotransferase enzyme family SNARE PF05739.14 CEH16553.1 - 0.052 13.2 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 SNARE domain Kinase-like PF14531.1 CEH16553.1 - 0.097 11.6 0.0 0.38 9.6 0.0 1.9 1 1 0 1 1 1 0 Kinase-like EcKinase PF02958.15 CEH16553.1 - 5.3 6.0 5.3 0.87 8.6 0.0 2.0 2 0 0 2 2 2 0 Ecdysteroid kinase NAD_binding_10 PF13460.1 CEH16555.1 - 9.5e-19 68.1 0.0 1.5e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CEH16555.1 - 3.4e-12 46.1 0.0 4.8e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CEH16555.1 - 1.4e-11 44.2 0.0 2.5e-10 40.1 0.1 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CEH16555.1 - 1.5e-11 43.5 0.1 6.6e-11 41.4 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CEH16555.1 - 7.3e-11 41.4 0.0 2.1e-09 36.7 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CEH16555.1 - 8.5e-08 31.4 0.2 0.00049 19.0 0.1 3.1 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 CEH16555.1 - 0.0012 17.8 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 CEH16555.1 - 0.0042 17.0 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 CEH16555.1 - 0.0091 15.9 0.0 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CEH16555.1 - 0.026 13.4 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 CEH16555.1 - 0.046 13.3 0.0 0.91 9.1 0.0 2.2 2 0 0 2 2 2 0 KR domain HMGL-like PF00682.14 CEH16557.1 - 3.5e-23 82.5 0.0 1.7e-22 80.2 0.0 1.9 1 1 1 2 2 2 1 HMGL-like Thiolase_C PF02803.13 CEH16558.1 - 2.1e-44 149.8 0.3 3.5e-44 149.1 0.2 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 CEH16558.1 - 1.8e-39 135.3 2.6 1.6e-38 132.2 0.4 2.2 1 1 1 2 2 2 2 Thiolase, N-terminal domain ACP_syn_III_C PF08541.5 CEH16558.1 - 0.0013 18.6 0.1 0.012 15.5 0.1 2.3 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal GPI-anchored PF10342.4 CEH16560.1 - 2.1e-09 37.7 0.1 2.1e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HRXXH PF13933.1 CEH16561.1 - 4.9e-77 258.6 0.0 6.3e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Zip PF02535.17 CEH16563.1 - 1.4e-38 132.6 12.6 1.4e-38 132.6 8.8 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Transmemb_17 PF09799.4 CEH16563.1 - 0.093 13.0 0.1 0.093 13.0 0.1 2.8 3 1 0 3 3 3 0 Predicted membrane protein SCP2 PF02036.12 CEH16564.1 - 0.0093 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family WD40 PF00400.27 CEH16566.1 - 7.6e-07 28.7 1.1 1.2e-05 24.9 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat XPG_I PF00867.13 CEH16567.1 - 1.2e-12 47.7 0.1 8e-12 45.0 0.1 2.3 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CEH16567.1 - 7.1e-05 22.9 0.1 0.0033 17.6 0.0 2.4 1 1 1 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 CEH16567.1 - 0.00056 19.4 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing HhH-GPD PF00730.20 CEH16568.1 - 7.2e-11 42.3 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UbiA PF01040.13 CEH16569.1 - 2.7e-29 102.1 22.6 4e-29 101.5 15.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family PRA1 PF03208.14 CEH16569.1 - 1.5 8.1 5.5 0.76 9.1 0.0 2.7 2 1 0 3 3 3 0 PRA1 family protein Cullin PF00888.17 CEH16570.1 - 1.4e-185 618.3 3.7 1.4e-185 618.3 2.5 1.3 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CEH16570.1 - 8.6e-28 95.9 4.5 8.6e-28 95.9 3.1 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2848 PF11010.3 CEH16570.1 - 0.014 14.8 0.1 0.033 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) HTH_27 PF13463.1 CEH16570.1 - 0.13 12.6 1.9 6.5 7.1 0.0 3.6 4 1 0 4 4 4 0 Winged helix DNA-binding domain Penicillinase_R PF03965.11 CEH16570.1 - 0.25 11.4 0.1 0.25 11.4 0.1 3.4 4 1 0 4 4 4 0 Penicillinase repressor Arv1 PF04161.8 CEH16571.1 - 6.6e-31 107.8 0.0 9.2e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Arv1-like family Neuregulin PF02158.10 CEH16571.1 - 0.13 11.0 0.1 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Neuregulin family HMGL-like PF00682.14 CEH16573.1 - 9.2e-64 215.3 0.0 1.3e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 CEH16573.1 - 1.8e-16 60.1 0.1 4.5e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain MAPEG PF01124.13 CEH16574.1 - 1.9e-07 30.7 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 MAPEG family adh_short_C2 PF13561.1 CEH16575.1 - 2.2e-25 89.8 0.0 2.7e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEH16575.1 - 4.6e-25 88.4 0.6 7.1e-25 87.8 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH16575.1 - 1.7e-12 47.3 0.3 2.9e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CEH16575.1 - 0.019 14.0 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RPAP2_Rtr1 PF04181.8 CEH16576.1 - 0.068 13.2 0.3 0.22 11.6 0.2 1.9 1 0 0 1 1 1 0 Rtr1/RPAP2 family COesterase PF00135.23 CEH16580.1 - 8.8e-89 298.6 0.0 1.4e-88 297.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CEH16580.1 - 1.1e-06 28.4 0.0 3.7e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Antimicrobial10 PF08105.6 CEH16580.1 - 0.1 12.2 0.3 1.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Metchnikowin family SET PF00856.23 CEH16581.1 - 2.6e-11 44.0 0.0 2.1e-09 37.8 0.0 2.8 2 1 0 2 2 2 1 SET domain Glyco_transf_15 PF01793.11 CEH16582.1 - 2.4e-106 355.4 0.0 3.1e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase P2_Phage_GpR PF06891.6 CEH16582.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) RAP1 PF07218.6 CEH16585.1 - 8.6 4.3 9.1 9.6 4.1 6.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ldh_1_N PF00056.18 CEH16586.1 - 2e-43 147.6 0.0 2.9e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CEH16586.1 - 1.8e-33 115.7 0.0 7.8e-33 113.6 0.0 1.9 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CEH16586.1 - 0.00078 18.2 0.0 0.0019 16.9 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 CEH16586.1 - 0.013 14.5 0.0 0.06 12.4 0.0 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 CEH16586.1 - 0.022 14.7 0.2 0.048 13.6 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 CEH16586.1 - 0.029 14.6 0.1 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 CEH16586.1 - 0.072 12.4 0.1 0.21 10.9 0.1 1.7 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase PRT_C PF08372.5 CEH16587.1 - 6.8e-07 28.9 0.6 1.4e-06 27.8 0.4 1.5 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal DUF3292 PF11696.3 CEH16587.1 - 1.6e-05 22.9 18.1 0.00015 19.8 0.2 4.2 4 0 0 4 4 4 3 Protein of unknown function (DUF3292) Reticulon PF02453.12 CEH16587.1 - 0.18 11.3 12.0 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 Reticulon PHD PF00628.24 CEH16589.1 - 3.8e-06 26.4 18.4 6.2e-06 25.8 12.8 1.3 1 0 0 1 1 1 1 PHD-finger Pet127 PF08634.5 CEH16591.1 - 7.1e-96 320.5 0.0 1e-95 320.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 POP1 PF06978.6 CEH16592.1 - 5.3e-35 120.7 1.7 5.3e-35 120.7 1.2 3.6 3 1 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CEH16592.1 - 3.2e-17 62.1 0.2 9.9e-17 60.5 0.0 2.0 2 0 0 2 2 2 1 POPLD (NUC188) domain Synaptonemal_3 PF15191.1 CEH16592.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 DUF1541 PF07563.6 CEH16592.1 - 0.15 11.7 1.0 0.32 10.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Hydrolase_6 PF13344.1 CEH16593.1 - 2.8e-32 110.5 0.0 5.4e-32 109.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEH16593.1 - 2.5e-16 59.1 0.0 4.5e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CEH16593.1 - 4.4e-11 43.6 0.0 9.4e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEH16593.1 - 4.3e-06 27.0 0.4 0.036 14.3 0.0 2.9 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Telomere_Sde2_2 PF13297.1 CEH16593.1 - 0.0079 15.4 0.1 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal LNS2 PF08235.8 CEH16593.1 - 0.015 14.8 0.0 0.061 12.8 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Acid_phosphat_B PF03767.9 CEH16593.1 - 0.026 13.8 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PGP_phosphatase PF09419.5 CEH16593.1 - 0.048 13.0 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase ACOX PF01756.14 CEH16594.1 - 4e-37 127.4 0.0 8.3e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CEH16594.1 - 1.8e-25 89.6 0.0 3.1e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CEH16594.1 - 2.3e-12 46.2 0.1 4.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CEH16594.1 - 0.00038 20.5 0.1 0.0015 18.6 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CEH16594.1 - 0.11 13.0 0.2 0.74 10.4 0.0 2.4 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, N-terminal domain DUF500 PF04366.7 CEH16596.1 - 8.7e-43 144.7 0.7 7e-42 141.8 0.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF500) Metallophos PF00149.23 CEH16597.1 - 1.7e-40 138.6 0.6 2.5e-40 138.0 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ubie_methyltran PF01209.13 CEH16598.1 - 3.4e-68 229.2 0.0 1.4e-37 129.1 0.0 2.3 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CEH16598.1 - 5.2e-12 46.0 0.0 5.2e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 CEH16598.1 - 2.2e-11 43.5 0.0 0.00012 21.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CEH16598.1 - 6.7e-11 42.5 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH16598.1 - 4e-08 33.1 0.0 6.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH16598.1 - 1.7e-07 31.5 0.0 7.6e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH16598.1 - 5e-07 30.2 0.0 1e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH16598.1 - 2.6e-06 27.4 0.0 9.5e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CEH16598.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase vATP-synt_AC39 PF01992.11 CEH16599.1 - 7.1e-94 314.6 0.0 8.3e-94 314.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Neocarzinostat PF00960.13 CEH16599.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Neocarzinostatin family Apc4 PF12896.2 CEH16600.1 - 3.7e-13 49.2 0.4 6.6e-13 48.4 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Trypsin_2 PF13365.1 CEH16601.1 - 0.026 14.5 0.1 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Trypsin-like peptidase domain PHD PF00628.24 CEH16602.1 - 8.1e-07 28.6 6.9 1.5e-06 27.7 4.8 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 CEH16602.1 - 0.00082 19.0 4.2 0.0016 18.1 2.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Toxin_51 PF15531.1 CEH16602.1 - 0.039 13.7 2.1 5.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Putative toxin 51 zf-HC5HC2H PF13771.1 CEH16602.1 - 0.06 13.5 0.7 0.14 12.2 0.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF2754 PF10953.3 CEH16602.1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) ADH_zinc_N PF00107.21 CEH16605.1 - 4e-13 49.0 0.2 7.4e-13 48.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH16605.1 - 1.7e-09 37.4 0.2 6.3e-09 35.5 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CEH16605.1 - 0.011 16.5 0.0 0.022 15.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MBOAT_2 PF13813.1 CEH16606.1 - 1.7e-07 31.1 1.0 4.2e-07 29.9 0.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family zf-CCHC PF00098.18 CEH16607.1 - 1.9e-07 30.6 2.1 3.6e-07 29.8 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CEH16607.1 - 0.00015 21.7 0.1 0.00015 21.7 0.1 3.2 3 1 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_5 PF14787.1 CEH16607.1 - 0.0008 18.8 1.3 0.0019 17.6 0.9 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RVP PF00077.15 CEH16607.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CEH16607.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF3802 PF12290.3 CEH16607.1 - 1.3 9.3 5.7 3.2 8.0 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) DUF4094 PF13334.1 CEH16607.1 - 6.8 7.1 8.3 2.9 8.3 3.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) FUSC PF04632.7 CEH16607.1 - 8.5 4.6 10.1 13 4.0 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family RVT_1 PF00078.22 CEH16608.1 - 1.9e-16 60.0 0.3 1e-15 57.6 0.2 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CEH16608.1 - 1.6e-14 53.2 0.5 3.2e-14 52.3 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CEH16608.1 - 2.3e-06 27.7 0.5 7.6e-06 26.0 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain Sugar_tr PF00083.19 CEH16613.1 - 2.6e-103 346.0 18.7 9.1e-103 344.2 13.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH16613.1 - 9.5e-25 87.0 26.4 7.9e-16 57.6 7.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PIP5K PF01504.13 CEH16615.1 - 4.5e-81 271.6 0.0 7.7e-81 270.9 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase adh_short PF00106.20 CEH16618.1 - 3e-23 82.5 0.8 8.9e-23 81.0 0.6 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH16618.1 - 2e-14 53.9 0.0 3e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH16618.1 - 4.7e-07 29.6 0.5 8e-07 28.8 0.4 1.4 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 CEH16618.1 - 0.024 14.4 0.2 0.072 12.9 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain LigB PF02900.13 CEH16619.1 - 2.4e-33 115.2 0.0 3.1e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase CBM_5_12_2 PF14600.1 CEH16619.1 - 0.0022 17.5 0.4 1.8 8.2 0.1 2.5 2 0 0 2 2 2 2 Cellulose-binding domain Voltage_CLC PF00654.15 CEH16626.1 - 1.2e-89 300.8 29.9 1.9e-89 300.1 20.8 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 CEH16626.1 - 1.1e-12 47.4 0.1 1.6e-08 34.1 0.1 2.5 2 0 0 2 2 2 2 CBS domain VPEP PF07589.6 CEH16626.1 - 0.44 10.5 5.0 13 5.9 0.6 3.4 2 0 0 2 2 2 0 PEP-CTERM motif Ras PF00071.17 CEH16627.1 - 1.4e-34 118.8 0.1 1.6e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH16627.1 - 2e-22 79.9 0.0 5e-22 78.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEH16627.1 - 3.3e-08 32.9 0.0 4.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEH16627.1 - 9.6e-08 31.4 0.1 1.2e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEH16627.1 - 0.00031 20.2 0.0 0.0031 16.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEH16627.1 - 0.0032 17.4 0.0 0.0056 16.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.6 CEH16627.1 - 0.0078 14.9 0.1 1.9 7.0 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 CEH16627.1 - 0.008 14.9 0.6 0.028 13.1 0.1 2.1 1 1 1 3 3 3 1 G-protein alpha subunit SRPRB PF09439.5 CEH16627.1 - 0.043 13.0 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PHP_C PF13263.1 CEH16627.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 PHP-associated DUF2554 PF10829.3 CEH16628.1 - 0.024 14.7 0.5 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) Med24_N PF11277.3 CEH16628.1 - 3.7 4.9 3.1 7.6 3.8 2.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Baculo_PEP_C PF04513.7 CEH16629.1 - 0.016 15.0 1.7 0.027 14.2 1.2 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HCV_NS4b PF01001.14 CEH16629.1 - 0.38 10.1 7.1 0.49 9.7 4.9 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b Podoplanin PF05808.6 CEH16629.1 - 1.2 8.7 12.7 0.46 10.0 3.8 2.1 1 1 1 2 2 2 0 Podoplanin Glycoprotein_B PF00606.13 CEH16629.1 - 6.7 4.6 6.5 7.2 4.4 4.5 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B G-alpha PF00503.15 CEH16631.1 - 1.9e-109 365.9 0.0 2.4e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CEH16631.1 - 8e-12 44.7 0.2 7.3e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 CEH16631.1 - 0.00049 20.5 0.0 0.35 11.3 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 CEH16631.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CEH16631.1 - 0.034 14.0 0.0 4.4 7.2 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CEH16631.1 - 0.037 13.5 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 CEH16631.1 - 0.038 13.1 1.0 5.6 6.0 0.1 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_21 PF13304.1 CEH16631.1 - 0.057 13.3 0.6 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Glyco_transf_28 PF03033.15 CEH16633.1 - 2.8e-17 62.7 0.0 6.2e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CEH16633.1 - 6.5e-05 22.3 0.0 0.052 13.0 0.0 2.4 2 0 0 2 2 2 2 GRAM domain UDPGT PF00201.13 CEH16633.1 - 0.00029 19.5 0.0 0.00046 18.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 CEH16633.1 - 0.0024 18.0 0.0 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 PH domain Prenyltransf PF01255.14 CEH16633.1 - 0.0046 16.1 0.0 0.036 13.1 0.0 2.3 3 0 0 3 3 3 1 Putative undecaprenyl diphosphate synthase PH_BEACH PF14844.1 CEH16633.1 - 0.013 15.3 0.0 6.2 6.7 0.0 2.9 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH dCMP_cyt_deam_1 PF00383.17 CEH16634.1 - 5.8e-08 32.3 0.2 4.5e-05 23.0 0.0 2.7 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region DnaJ PF00226.26 CEH16635.1 - 0.00064 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CEH16635.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Pam16 Transp_cyt_pur PF02133.10 CEH16636.1 - 5.7e-23 81.1 20.3 5.7e-23 81.1 14.1 2.3 3 0 0 3 3 3 1 Permease for cytosine/purines, uracil, thiamine, allantoin LEA_1 PF03760.10 CEH16636.1 - 4.4 7.5 13.7 0.034 14.2 3.7 1.7 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 Kelch_3 PF13415.1 CEH16637.1 - 3.1e-27 94.0 9.1 3.7e-06 26.9 0.0 7.5 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CEH16637.1 - 4e-27 93.7 10.8 1.1e-05 25.1 0.0 7.2 6 2 0 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.1 CEH16637.1 - 9.5e-22 76.6 0.0 9.5e-22 76.6 0.0 4.5 5 1 0 5 5 5 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.1 CEH16637.1 - 2.8e-17 62.2 4.4 0.0007 19.4 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 CEH16637.1 - 1.6e-14 53.3 6.9 0.00016 21.7 0.0 6.3 6 2 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 CEH16637.1 - 4.2e-09 35.8 1.0 0.00014 21.3 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CEH16637.1 - 5e-09 35.5 3.6 3.9e-05 23.2 0.1 4.8 6 0 0 6 6 6 2 Kelch motif Paramyxo_ncap PF00973.14 CEH16637.1 - 0.1 11.3 0.6 0.22 10.1 0.4 1.5 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein LIP PF03583.9 CEH16638.1 - 7.4e-56 189.4 0.0 1.1e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase DUF829 PF05705.9 CEH16638.1 - 0.0013 18.5 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Mito_carr PF00153.22 CEH16641.1 - 2.1e-36 123.5 1.8 9.4e-20 70.1 0.3 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.22 CEH16642.1 - 1.3e-11 43.9 0.1 1.5e-11 43.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein SKN1 PF03935.10 CEH16645.1 - 3e-175 583.1 0.0 4.1e-175 582.7 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) UQ_con PF00179.21 CEH16647.1 - 3e-44 149.8 0.0 3.4e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CEH16647.1 - 0.029 14.2 1.0 0.038 13.8 0.7 1.5 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 CEH16647.1 - 0.042 13.6 0.0 0.054 13.2 0.0 1.3 1 1 0 1 1 1 0 Prokaryotic E2 family B Cyt-b5 PF00173.23 CEH16648.1 - 3.1e-20 71.7 0.5 7.6e-20 70.4 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CEH16648.1 - 6.1e-09 36.2 22.6 7.8e-09 35.9 13.3 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3100 PF11299.3 CEH16648.1 - 0.12 11.5 4.1 0.11 11.7 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3100) Ribosomal_L18p PF00861.17 CEH16650.1 - 6.5e-43 145.7 0.1 2.5e-42 143.8 0.0 2.0 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CEH16650.1 - 1.8e-28 98.9 6.1 1.8e-28 98.9 4.2 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 CEH16650.1 - 0.014 15.3 0.2 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Threonine synthase N terminus Ribosomal_L15e PF00827.12 CEH16651.1 - 1.6e-88 295.2 8.5 1.8e-88 295.0 5.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Cys_Met_Meta_PP PF01053.15 CEH16653.1 - 3e-117 391.1 0.0 1.7e-113 378.8 0.0 2.1 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CEH16653.1 - 0.0047 15.9 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 CEH16653.1 - 0.0054 15.0 0.0 0.0071 14.6 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Glyco_hydro_3 PF00933.16 CEH16654.1 - 9e-62 208.7 0.0 9.6e-42 142.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CEH16654.1 - 1.2e-48 165.5 0.0 1.8e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CEH16654.1 - 4.1e-15 55.4 0.0 8.5e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ThuA PF06283.6 CEH16655.1 - 2.8e-46 157.9 0.0 6.2e-46 156.8 0.0 1.5 1 1 0 1 1 1 1 Trehalose utilisation TPR_1 PF00515.23 CEH16656.1 - 5.5e-23 79.5 1.9 1.6e-08 33.7 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 CEH16656.1 - 6.1e-23 80.2 19.8 1.1e-13 50.6 0.1 3.7 3 1 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 CEH16656.1 - 2.1e-22 77.1 14.7 1.1e-06 28.1 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 CEH16656.1 - 3.8e-15 54.4 0.1 0.0027 17.3 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 CEH16656.1 - 1.8e-13 49.5 3.7 6.9e-05 22.7 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEH16656.1 - 4.5e-13 48.5 19.6 0.00018 21.8 0.7 6.7 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 CEH16656.1 - 5.8e-12 45.9 13.3 6.6e-08 33.0 0.1 5.9 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 CEH16656.1 - 7.7e-11 41.7 4.6 3.3e-06 26.9 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CEH16656.1 - 2.2e-08 34.3 17.7 0.0011 19.1 0.4 5.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEH16656.1 - 6.1e-06 25.6 8.3 0.011 15.4 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 CEH16656.1 - 2.6e-05 24.3 8.1 2 9.0 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CEH16656.1 - 0.00033 20.7 5.4 0.0027 17.8 0.6 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CEH16656.1 - 0.0012 17.9 2.6 0.74 8.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Coatomer_E PF04733.9 CEH16656.1 - 0.0058 15.8 1.1 0.33 10.0 0.1 3.0 2 1 0 2 2 2 1 Coatomer epsilon subunit TPR_9 PF13371.1 CEH16656.1 - 0.057 13.2 8.0 1.3 8.8 0.7 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 CEH16656.1 - 0.67 10.1 20.1 0.18 11.9 0.5 4.8 5 1 1 6 6 4 0 Tetratricopeptide repeat MIT PF04212.13 CEH16656.1 - 7.7 6.4 9.3 3.2 7.6 0.3 4.2 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain NDK PF00334.14 CEH16658.1 - 1.6e-53 180.0 0.0 1.9e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Peptidase_S9 PF00326.16 CEH16659.1 - 1.7e-06 27.4 0.1 4.3e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CEH16659.1 - 2.4e-06 27.3 1.1 2.9e-05 23.8 0.2 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family BON PF04972.12 CEH16659.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 BON domain DSBA PF01323.15 CEH16661.1 - 2.5e-06 27.1 0.4 2.1e-05 24.1 0.1 1.9 1 1 1 2 2 2 1 DSBA-like thioredoxin domain DUF2320 PF10082.4 CEH16661.1 - 0.018 13.7 0.1 0.031 13.0 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2320) Thioredoxin_4 PF13462.1 CEH16661.1 - 0.09 12.7 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Pex14_N PF04695.8 CEH16662.1 - 0.011 15.7 2.0 0.015 15.3 1.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SSP160 PF06933.6 CEH16662.1 - 0.37 8.7 17.3 0.38 8.6 12.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Golgin_A5 PF09787.4 CEH16662.1 - 4.2 5.7 7.2 4.9 5.5 5.0 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF605 PF04652.11 CEH16662.1 - 5.2 6.3 9.0 5.6 6.2 6.2 1.0 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 CEH16662.1 - 5.7 5.4 11.5 6.2 5.3 7.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF822 PF05687.8 CEH16663.1 - 0.54 10.6 5.1 0.73 10.1 3.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Arrestin_C PF02752.17 CEH16664.1 - 9.2e-11 41.9 0.9 1.3e-09 38.3 0.1 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEH16664.1 - 4.2e-05 23.4 0.4 0.28 11.0 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain NDUF_B12 PF08122.7 CEH16664.1 - 0.23 11.1 0.1 0.48 10.1 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family Ribosomal_L24e PF01246.15 CEH16665.1 - 2.5e-33 113.7 1.0 2.5e-33 113.7 0.7 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e DUF4407 PF14362.1 CEH16665.1 - 0.029 13.3 7.2 0.034 13.0 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM117 PF15388.1 CEH16665.1 - 0.29 10.3 4.2 0.33 10.1 2.9 1.1 1 0 0 1 1 1 0 Protein Family FAM117 COX16 PF14138.1 CEH16665.1 - 0.5 10.5 2.9 2.5 8.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 PVL_ORF50 PF07768.6 CEH16665.1 - 0.77 9.7 5.7 1.2 9.1 3.9 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family ATP-synt_E PF05680.7 CEH16665.1 - 2.9 7.9 10.1 11 6.0 7.0 1.9 1 1 0 1 1 1 0 ATP synthase E chain Ribosomal_L38e PF01781.13 CEH16666.1 - 4.8e-34 115.9 2.0 6.8e-34 115.4 1.4 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family adh_short PF00106.20 CEH16667.1 - 5.9e-28 97.8 2.1 9.9e-28 97.1 1.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH16667.1 - 4.2e-11 42.8 0.8 7.3e-11 42.0 0.5 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 CEH16667.1 - 0.00019 20.2 0.0 0.0003 19.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CEH16667.1 - 0.0002 20.9 0.3 0.00039 19.9 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEH16667.1 - 0.0014 18.6 0.6 0.0034 17.4 0.4 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 CEH16667.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OTU PF02338.14 CEH16669.1 - 0.077 13.5 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 OTU-like cysteine protease MIP PF00230.15 CEH16672.1 - 4.9e-42 143.9 4.9 6.3e-42 143.5 3.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pirin PF02678.11 CEH16673.1 - 2.2e-31 107.8 0.1 4.8e-31 106.7 0.0 1.6 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 CEH16673.1 - 1.5e-16 60.3 0.0 3.3e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 CEH16673.1 - 0.0055 16.1 3.8 0.031 13.7 0.9 2.3 2 0 0 2 2 2 1 Cupin domain zf-C2H2_4 PF13894.1 CEH16676.1 - 1e-06 28.6 5.4 0.009 16.2 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEH16676.1 - 4.6e-05 23.5 12.2 0.011 16.0 1.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEH16676.1 - 0.00013 22.0 1.7 0.00013 22.0 1.2 3.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-CHCC PF10276.4 CEH16676.1 - 0.046 13.5 0.2 0.086 12.6 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger domain Sec23_trunk PF04811.10 CEH16677.1 - 6.4e-76 254.9 0.0 9.4e-76 254.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CEH16677.1 - 1.8e-35 120.4 0.2 3.5e-35 119.5 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CEH16677.1 - 4e-31 107.3 0.0 7.5e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CEH16677.1 - 6e-17 60.9 6.2 1.2e-16 59.9 4.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CEH16677.1 - 4.5e-13 48.6 0.0 1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat tRNA-synt_1b PF00579.20 CEH16678.1 - 9e-72 241.6 0.0 1.2e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WH1 PF00568.18 CEH16679.1 - 7.1e-17 61.1 0.0 9.8e-17 60.6 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 CEH16679.1 - 3.1e-08 33.8 0.1 7.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain DUF605 PF04652.11 CEH16679.1 - 0.0011 18.4 25.8 0.002 17.5 17.9 1.5 1 0 0 1 1 1 1 Vta1 like WH2 PF02205.15 CEH16679.1 - 0.0041 16.6 0.3 0.013 15.0 0.2 2.0 1 0 0 1 1 1 1 WH2 motif PAT1 PF09770.4 CEH16679.1 - 8.1 4.5 12.7 10 4.2 8.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Aa_trans PF01490.13 CEH16680.1 - 1.5e-31 109.3 29.1 2e-31 108.9 20.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CEH16680.1 - 4.4e-06 25.7 9.1 4.4e-06 25.7 6.3 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2613 PF11021.3 CEH16680.1 - 0.99 9.1 0.0 0.99 9.1 0.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2613) SGT1 PF07093.6 CEH16681.1 - 4.1e-74 250.0 22.3 2.9e-65 220.8 11.5 3.0 2 1 0 2 2 2 2 SGT1 protein WD40 PF00400.27 CEH16682.1 - 0.00044 20.0 1.5 2.8 7.9 0.1 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Glypican PF01153.14 CEH16682.1 - 1.6 7.2 4.6 2.4 6.6 3.2 1.1 1 0 0 1 1 1 0 Glypican DUF3357 PF11837.3 CEH16683.1 - 0.69 9.7 3.9 0.67 9.8 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) DUF1616 PF07760.6 CEH16683.1 - 3.7 6.6 7.7 0.27 10.3 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1616) R3H-assoc PF13902.1 CEH16685.1 - 0.049 13.5 2.9 0.05 13.5 0.1 2.1 2 0 0 2 2 2 0 R3H-associated N-terminal domain Acetyltransf_3 PF13302.1 CEH16686.1 - 1.9e-24 86.4 0.0 2.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CEH16686.1 - 1.3e-06 28.3 0.6 0.00069 19.5 0.2 2.4 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEH16686.1 - 0.0037 16.9 0.0 0.032 13.9 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.19 CEH16686.1 - 0.027 14.4 0.0 9.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family PHA_gran_rgn PF09650.5 CEH16686.1 - 0.075 13.1 0.3 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) cNMP_binding PF00027.24 CEH16687.1 - 6.9e-37 125.1 0.0 4.9e-15 55.1 0.0 5.4 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.17 CEH16687.1 - 1.5e-17 64.2 1.3 8.4e-12 45.4 0.4 3.3 3 0 0 3 3 3 2 Patatin-like phospholipase RNase_PH PF01138.16 CEH16688.1 - 7.6e-22 78.0 0.1 1.4e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Kinesin PF00225.18 CEH16690.1 - 1.2e-46 158.9 0.0 1.4e-24 86.4 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain AAA_33 PF13671.1 CEH16690.1 - 0.16 11.8 1.9 0.24 11.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain Polyketide_cyc2 PF10604.4 CEH16697.1 - 4.3e-07 30.1 0.2 5.7e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 CEH16697.1 - 0.006 16.6 0.2 0.008 16.2 0.2 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Suc_Fer-like PF06999.7 CEH16699.1 - 1.3e-29 103.8 0.4 1e-24 87.8 0.0 2.7 1 1 1 2 2 2 2 Sucrase/ferredoxin-like IL12p40_C PF10420.4 CEH16699.1 - 0.013 15.5 0.1 0.031 14.3 0.1 1.6 1 0 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus Hormone_6 PF00236.13 CEH16699.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 2 0 0 2 2 2 0 Glycoprotein hormone POTRA_1 PF08478.5 CEH16701.1 - 0.14 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 POTRA domain, FtsQ-type AhpC-TSA PF00578.16 CEH16702.1 - 1.4e-24 86.1 0.0 2.3e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CEH16702.1 - 5e-14 52.0 0.0 1.5e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Redoxin Patatin PF01734.17 CEH16705.1 - 7.4e-23 81.5 0.0 1.9e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase FlgM PF04316.8 CEH16705.1 - 0.22 11.4 3.3 5.3 7.0 0.0 3.1 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM OTU PF02338.14 CEH16706.1 - 0.084 13.4 0.5 0.33 11.5 0.0 2.2 2 0 0 2 2 2 0 OTU-like cysteine protease Peptidase_M43 PF05572.8 CEH16707.1 - 3.4e-14 52.7 0.0 5.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 CEH16707.1 - 8.2e-05 22.6 0.0 0.00031 20.7 0.0 1.9 1 1 1 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CEH16707.1 - 0.002 18.2 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CEH16707.1 - 0.0032 17.0 0.1 0.0062 16.0 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 CEH16707.1 - 0.12 11.6 0.5 1.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Mito_carr PF00153.22 CEH16708.1 - 2.3e-44 149.0 0.5 1e-14 54.0 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein CAF-1_p150 PF11600.3 CEH16708.1 - 2.6 7.3 10.1 3.9 6.7 7.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sporozoite_P67 PF05642.6 CEH16708.1 - 5.9 4.6 11.7 9.1 4.0 8.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen eIF3_subunit PF08597.5 CEH16709.1 - 1.4e-34 119.8 13.0 1.5e-34 119.6 9.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Isy1 PF06246.7 CEH16709.1 - 0.022 14.1 0.0 0.022 14.1 0.0 2.2 2 1 0 2 2 2 0 Isy1-like splicing family HMG_box PF00505.14 CEH16709.1 - 0.14 12.4 0.3 0.14 12.4 0.2 2.7 3 0 0 3 3 3 0 HMG (high mobility group) box PBP1_TM PF14812.1 CEH16709.1 - 0.67 10.3 16.3 0.16 12.2 0.7 3.1 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPPII_N PF12583.3 CEH16709.1 - 2.4 8.2 6.8 1.9 8.5 0.5 2.4 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal ERO1 PF04137.10 CEH16710.1 - 5.6e-125 417.0 0.0 7.8e-125 416.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CENP-C_C PF11699.3 CEH16711.1 - 1.2e-25 89.3 0.0 1.9e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 CEH16711.1 - 0.00015 21.1 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Pyridoxal_deC PF00282.14 CEH16712.1 - 7.9e-18 64.0 0.0 8.5e-16 57.3 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CEH16712.1 - 2.5e-08 33.0 0.0 5.3e-08 31.9 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CEH16712.1 - 9.8e-07 28.1 0.1 1.6e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.20 CEH16713.1 - 4.2e-37 127.6 0.0 7.4e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinetochor_Ybp2 PF08568.5 CEH16713.1 - 9.2e-12 44.0 0.0 8e-06 24.3 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Pkinase_Tyr PF07714.12 CEH16713.1 - 1.1e-10 41.0 0.0 2.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH16713.1 - 2.1e-05 24.4 0.0 2.1e-05 24.4 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CEH16713.1 - 0.0032 17.0 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CEH16713.1 - 2.8 6.6 0.1 4.1 6.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Abhydrolase_1 PF00561.15 CEH16714.1 - 1.6e-26 93.2 0.2 8.6e-24 84.3 0.2 3.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 CEH16714.1 - 0.023 14.5 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein CN_hydrolase PF00795.17 CEH16715.1 - 1.4e-27 96.2 0.0 2.2e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 CEH16715.1 - 6.5e-21 74.3 0.0 3e-17 62.3 0.0 2.2 2 0 0 2 2 2 2 NAD synthase DUF2597 PF10772.4 CEH16716.1 - 0.0011 18.9 0.0 0.031 14.1 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2597) RPEL PF02755.10 CEH16716.1 - 0.14 11.5 0.5 0.32 10.3 0.3 1.6 1 0 0 1 1 1 0 RPEL repeat MULE PF10551.4 CEH16717.1 - 3.3e-23 81.6 0.1 6.9e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 CEH16717.1 - 2.6e-06 26.2 0.4 5.9e-06 25.0 0.3 1.5 2 0 0 2 2 2 1 Transposase, Mutator family Toxin_trans PF07952.7 CEH16717.1 - 0.36 9.6 0.5 0.55 9.0 0.3 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Asn_synthase PF00733.16 CEH16719.1 - 9.4e-67 225.1 0.3 2.1e-66 224.0 0.2 1.6 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CEH16719.1 - 9.3e-38 128.7 0.0 1.5e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CEH16719.1 - 5.1e-30 104.1 0.0 9.3e-29 100.0 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CEH16719.1 - 1.5e-06 27.1 0.0 0.0047 15.6 0.0 3.0 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 CEH16719.1 - 5e-05 22.6 0.0 8.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.8 CEH16719.1 - 0.059 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 CEH16719.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NAD synthase DUF3237 PF11578.3 CEH16720.1 - 4.2e-20 71.5 0.0 4.9e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) GFA PF04828.9 CEH16721.1 - 1.2e-15 57.2 0.0 1.6e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Rhomboid PF01694.17 CEH16722.1 - 3.7e-21 75.6 7.8 3.7e-21 75.6 5.4 1.6 2 0 0 2 2 2 1 Rhomboid family IBN_N PF03810.14 CEH16723.1 - 1.2e-11 44.3 0.1 9.3e-11 41.4 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 CEH16723.1 - 4.9e-05 22.0 0.0 0.0001 21.0 0.0 1.5 1 0 0 1 1 1 1 Cse1 HEAT PF02985.17 CEH16723.1 - 0.015 15.3 0.0 0.32 11.1 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat Xpo1 PF08389.7 CEH16723.1 - 0.028 14.3 0.0 0.13 12.1 0.0 2.2 1 0 0 1 1 1 0 Exportin 1-like protein HYLS1_C PF15311.1 CEH16723.1 - 0.07 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus Peptidase_S26 PF10502.4 CEH16724.1 - 1.1e-09 37.9 0.0 1.6e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 CEH16724.1 - 8.8e-09 34.8 0.0 2.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase S24-like MFS_1 PF07690.11 CEH16725.1 - 1.4e-22 79.8 43.4 1.4e-22 79.8 30.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 CEH16725.1 - 0.022 14.0 0.2 0.074 12.3 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Peptidase_M28 PF04389.12 CEH16727.1 - 7.2e-33 113.8 0.0 1.2e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Phage_Coat_A PF05357.8 CEH16728.1 - 4.6e-05 22.8 0.4 6.5e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 Phage Coat Protein A DUF3767 PF12597.3 CEH16729.1 - 3.3e-23 81.5 0.1 4e-23 81.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Herpes_gE PF02480.11 CEH16730.1 - 0.078 11.2 0.0 0.093 10.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PgaD PF13994.1 CEH16730.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein DUF3357 PF11837.3 CEH16730.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Lipase_3 PF01764.20 CEH16731.1 - 4e-24 84.8 0.0 5.8e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 CEH16731.1 - 0.0081 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 CEH16731.1 - 0.0084 15.8 0.1 0.018 14.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CEH16731.1 - 0.082 12.1 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.3 CEH16731.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FUSC_2 PF13515.1 CEH16732.1 - 4.3e-16 58.9 8.5 4.3e-16 58.9 5.9 2.8 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 CEH16732.1 - 4.7e-11 41.8 1.2 4.7e-11 41.8 0.8 4.6 5 0 0 5 5 5 2 Fusaric acid resistance protein family ALMT PF11744.3 CEH16732.1 - 2e-10 39.9 0.4 9.2e-07 27.8 0.1 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 CEH16732.1 - 3.1e-08 33.5 0.0 8.8e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF2076 PF09849.4 CEH16732.1 - 1.3e-06 28.7 9.1 4.5e-06 26.8 6.3 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CEH16732.1 - 0.00077 19.3 5.0 0.0015 18.3 3.5 1.5 1 0 0 1 1 1 1 CHCH domain DUF2422 PF10337.4 CEH16732.1 - 0.0063 15.3 3.0 0.25 10.0 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2422) ELO PF01151.13 CEH16733.1 - 1.6e-61 207.7 4.2 2e-61 207.5 2.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF218 PF02698.12 CEH16734.1 - 2.4e-17 62.8 0.1 3.4e-16 59.1 0.1 2.1 1 1 0 1 1 1 1 DUF218 domain Peroxidase_2 PF01328.12 CEH16734.1 - 0.031 12.9 0.0 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 Peroxidase, family 2 ATPgrasp_Ter PF15632.1 CEH16735.1 - 1.9e-05 23.5 0.0 0.0069 15.1 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CEH16735.1 - 2.3e-05 24.2 0.0 4.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding_2 PF13380.1 CEH16735.1 - 0.0085 16.2 0.0 0.091 12.9 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_3 PF02655.9 CEH16735.1 - 0.06 13.2 0.0 0.32 10.8 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp domain Acatn PF13000.2 CEH16736.1 - 2.8e-137 458.5 26.9 4e-68 230.2 7.5 4.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Fumble PF03630.9 CEH16737.1 - 1e-108 363.2 0.0 1.1e-84 284.2 0.0 3.1 3 0 0 3 3 3 3 Fumble AAA_18 PF13238.1 CEH16738.1 - 9.9e-05 22.6 0.2 0.00085 19.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CEH16738.1 - 0.0014 18.9 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 CEH16738.1 - 0.0052 17.6 0.0 0.017 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 CEH16738.1 - 0.0065 16.0 0.1 0.07 12.6 0.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CbiA PF01656.18 CEH16738.1 - 0.012 15.0 0.1 0.45 9.8 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SE PF00437.15 CEH16738.1 - 0.093 11.6 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 CEH16738.1 - 0.13 12.2 0.1 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CEH16738.1 - 0.15 11.2 0.1 0.65 9.1 0.0 1.9 1 1 1 2 2 2 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 CEH16738.1 - 0.15 11.7 0.1 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase p450 PF00067.17 CEH16739.1 - 8.6e-26 90.4 0.0 3e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2189 PF09955.4 CEH16739.1 - 0.047 13.6 0.9 0.7 9.8 0.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) PSD4 PF07631.6 CEH16739.1 - 0.098 13.0 0.2 0.45 10.8 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1592) Metallothio_Pro PF02069.11 CEH16741.1 - 0.061 13.1 1.9 0.14 12.0 1.3 1.5 1 0 0 1 1 1 0 Prokaryotic metallothionein TraT PF05818.7 CEH16742.1 - 0.079 12.3 1.1 0.1 12.0 0.7 1.4 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein TFIIB PF00382.14 CEH16743.1 - 1.1e-30 105.2 4.3 5.1e-18 64.6 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CEH16743.1 - 3.1e-12 45.6 0.5 5e-12 44.9 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 CEH16743.1 - 0.014 14.9 0.2 0.094 12.2 0.1 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain Cyclin_C PF02984.14 CEH16743.1 - 0.036 13.9 0.3 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain zf-ribbon_3 PF13248.1 CEH16743.1 - 0.11 11.7 0.3 0.2 10.8 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain AAA_2 PF07724.9 CEH16746.1 - 3.9e-42 144.0 0.0 2.3e-38 131.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CEH16746.1 - 1.3e-26 92.2 0.0 5.5e-26 90.2 0.0 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CEH16746.1 - 1.2e-20 74.0 0.0 3.5e-10 40.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CEH16746.1 - 3.7e-12 46.1 0.1 1.1e-06 28.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CEH16746.1 - 1.8e-11 43.7 0.1 5.7e-08 32.4 0.0 2.5 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.1 CEH16746.1 - 2.8e-10 40.4 2.7 0.0023 18.0 0.0 4.5 3 2 1 4 4 3 2 AAA domain AAA_16 PF13191.1 CEH16746.1 - 1e-09 38.6 23.6 0.00029 20.8 0.1 6.5 3 2 3 6 6 4 3 AAA ATPase domain IstB_IS21 PF01695.12 CEH16746.1 - 3.1e-07 29.9 0.9 0.00054 19.4 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_19 PF13245.1 CEH16746.1 - 6e-07 29.1 0.1 0.032 13.9 0.1 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 CEH16746.1 - 7.1e-06 26.3 0.0 0.26 11.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CEH16746.1 - 1.8e-05 23.9 0.0 0.00082 18.5 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 CEH16746.1 - 2.6e-05 24.0 2.9 0.0031 17.2 0.0 3.4 3 1 0 3 3 2 1 Archaeal ATPase AAA_14 PF13173.1 CEH16746.1 - 3.6e-05 23.6 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CEH16746.1 - 7.4e-05 23.5 6.3 0.29 11.9 0.0 3.9 3 1 0 3 3 2 2 AAA domain MobB PF03205.9 CEH16746.1 - 0.00014 21.6 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 CEH16746.1 - 0.00018 21.3 0.0 0.17 11.7 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_3 PF07726.6 CEH16746.1 - 0.00032 20.3 0.0 0.005 16.4 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 CEH16746.1 - 0.00044 19.7 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 CEH16746.1 - 0.00078 18.1 0.0 0.088 11.4 0.0 2.7 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 CEH16746.1 - 0.0011 18.2 0.1 0.38 9.8 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 CEH16746.1 - 0.0014 18.2 0.0 2.8 7.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CEH16746.1 - 0.0015 18.6 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase T2SE PF00437.15 CEH16746.1 - 0.0024 16.8 0.0 0.035 13.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein CbiA PF01656.18 CEH16746.1 - 0.0031 16.9 0.0 1.3 8.4 0.0 2.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Rho_Binding PF08912.6 CEH16746.1 - 0.0031 17.7 1.6 0.0088 16.3 1.1 1.8 1 0 0 1 1 1 1 Rho Binding AAA_28 PF13521.1 CEH16746.1 - 0.0036 17.2 4.6 2 8.3 0.0 4.0 4 1 1 5 5 3 1 AAA domain DUF815 PF05673.8 CEH16746.1 - 0.0042 16.0 0.6 0.48 9.2 0.0 3.4 3 2 0 3 3 3 1 Protein of unknown function (DUF815) TIP49 PF06068.8 CEH16746.1 - 0.0046 15.7 0.3 1.7 7.2 0.0 2.8 3 0 0 3 3 3 1 TIP49 C-terminus DUF853 PF05872.7 CEH16746.1 - 0.011 14.1 0.0 1 7.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Torsin PF06309.6 CEH16746.1 - 0.014 15.2 0.0 0.061 13.2 0.0 1.9 2 0 0 2 2 2 0 Torsin AAA_24 PF13479.1 CEH16746.1 - 0.019 14.5 0.0 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CEH16746.1 - 0.019 14.6 0.3 0.36 10.4 0.0 2.7 3 0 0 3 3 2 0 NACHT domain TBPIP PF07106.8 CEH16746.1 - 0.028 13.9 6.7 0.066 12.7 4.7 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UPF0079 PF02367.12 CEH16746.1 - 0.066 12.8 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DNA_pol3_delta2 PF13177.1 CEH16746.1 - 0.068 12.8 0.0 1.5 8.4 0.0 2.6 2 1 0 2 2 2 0 DNA polymerase III, delta subunit PhoH PF02562.11 CEH16746.1 - 0.082 12.1 0.0 3 7.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 CEH16746.1 - 0.14 12.0 3.4 2.5 7.9 0.0 3.4 3 1 0 3 3 2 0 AAA domain V_ATPase_I PF01496.14 CEH16746.1 - 0.14 9.9 7.4 0.21 9.4 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.12 CEH16746.1 - 0.2 11.4 2.9 16 5.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 APG6 PF04111.7 CEH16746.1 - 0.3 10.0 8.0 0.57 9.1 5.6 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1090 PF06476.7 CEH16746.1 - 0.36 10.5 8.8 0.66 9.6 4.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) EHN PF06441.7 CEH16746.1 - 0.65 9.9 2.4 1.7 8.6 0.2 2.6 2 1 1 3 3 3 0 Epoxide hydrolase N terminus Cupin_1 PF00190.17 CEH16747.1 - 1.3e-26 92.7 0.0 2e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 CEH16747.1 - 9.1e-26 89.1 1.2 8e-15 54.1 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 CEH16747.1 - 3.1e-09 36.0 0.1 0.0003 20.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 CEH16747.1 - 4.9e-09 35.9 0.3 0.0026 17.4 0.1 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 CEH16747.1 - 8.5e-06 25.4 0.0 0.005 16.4 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase Cupin_6 PF12852.2 CEH16747.1 - 8.9e-05 22.1 0.1 0.19 11.3 0.0 2.2 2 0 0 2 2 2 2 Cupin 3-HAO PF06052.7 CEH16747.1 - 0.029 13.8 0.0 9.5 5.6 0.0 2.5 2 1 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase SBP56 PF05694.6 CEH16751.1 - 2.7e-10 39.3 0.0 4.6e-09 35.2 0.0 2.7 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 CEH16751.1 - 0.002 17.2 0.0 2.5 7.0 0.0 2.7 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.6 CEH16751.1 - 0.0084 15.0 0.1 0.14 11.0 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) Cellulase PF00150.13 CEH16752.1 - 2.3e-13 50.0 0.1 7.4e-13 48.3 0.1 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ERG4_ERG24 PF01222.12 CEH16753.1 - 5.2e-131 437.1 21.3 6.2e-131 436.8 14.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Sterol-sensing PF12349.3 CEH16753.1 - 1.4 8.4 9.8 1.5 8.3 1.1 3.0 3 0 0 3 3 3 0 Sterol-sensing domain of SREBP cleavage-activation Ras PF00071.17 CEH16755.1 - 2.1e-56 189.7 0.0 2.5e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH16755.1 - 6.2e-16 58.9 0.0 8.5e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH16755.1 - 5.8e-07 28.9 0.0 9.5e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CEH16755.1 - 0.0003 20.0 0.0 0.00041 19.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CEH16755.1 - 0.064 12.3 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DNA_pol_B PF00136.16 CEH16756.1 - 8e-149 496.3 0.5 1.3e-148 495.7 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CEH16756.1 - 3.9e-86 288.8 0.0 1.2e-85 287.2 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CEH16756.1 - 2.1e-20 72.4 5.3 4.5e-20 71.4 3.7 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 CEH16756.1 - 0.0027 17.5 0.1 0.0086 15.8 0.1 2.0 1 1 0 1 1 1 1 RNase_H superfamily zf-RING-like PF08746.6 CEH16756.1 - 0.023 14.7 1.3 0.023 14.7 0.9 2.1 2 0 0 2 2 2 0 RING-like domain DNA_pol_B_2 PF03175.8 CEH16756.1 - 0.057 12.0 0.7 0.23 10.0 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral Alg6_Alg8 PF03155.10 CEH16757.1 - 5.8e-108 361.7 20.3 2.7e-53 181.4 0.6 3.0 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family Phage_term_sma PF07141.6 CEH16758.1 - 2.5 7.6 7.2 8.6 5.8 0.1 3.3 2 1 1 4 4 4 0 Putative bacteriophage terminase small subunit UPF0047 PF01894.12 CEH16760.1 - 1.9e-38 130.8 0.1 2.2e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Hpt PF01627.18 CEH16761.1 - 2.3e-10 40.3 0.0 4e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Hpt domain Zn_clus PF00172.13 CEH16762.1 - 0.0051 16.6 7.8 0.011 15.5 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Grp1_Fun34_YaaH PF01184.14 CEH16763.1 - 5e-60 202.4 18.5 6.3e-60 202.0 12.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Grp1_Fun34_YaaH PF01184.14 CEH16764.1 - 3.4e-23 82.0 9.8 4.3e-23 81.7 6.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family EXS PF03124.9 CEH16765.1 - 4.5e-84 282.4 19.4 5.8e-84 282.0 13.4 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CEH16765.1 - 1.1e-44 153.2 0.7 1.8e-44 152.5 0.5 1.3 1 0 0 1 1 1 1 SPX domain Porin_3 PF01459.17 CEH16766.1 - 9.6e-56 189.0 0.4 1.1e-55 188.9 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Motile_Sperm PF00635.21 CEH16768.1 - 1.1e-25 89.3 0.1 1.8e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Med3 PF11593.3 CEH16768.1 - 1.2 8.3 9.8 1.3 8.1 6.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.20 CEH16769.1 - 5.4e-34 117.5 0.0 6.8e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH16769.1 - 8.4e-13 47.9 0.0 1.1e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH16769.1 - 4.2e-05 23.3 0.2 0.63 9.7 0.0 3.2 4 0 0 4 4 4 2 Phosphotransferase enzyme family Ras PF00071.17 CEH16771.1 - 1.2e-47 161.3 0.0 1.4e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH16771.1 - 1.4e-19 70.7 0.0 3.5e-19 69.4 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CEH16771.1 - 7.6e-06 25.4 0.0 2.5e-05 23.8 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CEH16771.1 - 1.4e-05 24.3 0.0 1.5e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CEH16771.1 - 6e-05 22.9 0.0 8.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 CEH16771.1 - 0.11 11.9 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zip PF02535.17 CEH16772.1 - 9.4e-42 143.1 2.8 1.2e-41 142.7 2.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter HemY_N PF07219.8 CEH16772.1 - 0.049 13.1 1.0 0.099 12.2 0.0 2.0 2 0 0 2 2 2 0 HemY protein N-terminus ABC1 PF03109.11 CEH16775.1 - 2.2e-30 105.0 0.3 4.2e-30 104.1 0.2 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CEH16775.1 - 0.00034 20.0 0.1 0.00077 18.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.6 CEH16775.1 - 0.0028 16.9 0.1 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 CEH16775.1 - 0.003 17.3 0.2 0.028 14.1 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 CEH16775.1 - 0.006 15.7 0.2 0.043 12.9 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Fer4 PF00037.22 CEH16776.1 - 4.7e-15 54.4 18.4 2.1e-09 36.5 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 CEH16776.1 - 1.6e-12 47.6 11.5 2.5e-12 46.9 8.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CEH16776.1 - 7.8e-11 41.6 23.2 1.7e-08 34.1 9.0 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 CEH16776.1 - 8.3e-11 42.4 6.9 1.3e-05 25.7 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 CEH16776.1 - 4.8e-10 39.5 11.6 8.2e-10 38.7 8.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 CEH16776.1 - 6.5e-10 38.7 5.3 7.2e-05 22.5 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 CEH16776.1 - 1.2e-09 38.3 2.2 0.00016 21.9 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 CEH16776.1 - 2.2e-08 33.5 15.4 8.2e-05 22.2 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 CEH16776.1 - 2.6e-08 33.3 18.8 0.00022 20.9 3.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 CEH16776.1 - 4.9e-08 32.8 19.5 1.4e-05 24.9 8.1 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 CEH16776.1 - 1.2e-07 31.4 12.5 0.00085 19.4 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 CEH16776.1 - 1.3e-05 25.6 7.7 0.0055 17.2 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 CEH16776.1 - 2e-05 24.9 10.4 0.027 14.8 0.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 CEH16776.1 - 0.00081 19.7 13.8 0.077 13.3 1.2 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 CEH16776.1 - 0.0042 17.5 19.4 0.0075 16.7 4.1 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_11 PF13247.1 CEH16776.1 - 0.12 12.2 4.5 0.22 11.4 3.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.5 CEH16776.1 - 0.31 11.1 5.9 2.2 8.4 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain DSPc PF00782.15 CEH16778.1 - 2.7e-24 85.2 0.0 3e-23 81.8 0.0 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEH16778.1 - 0.0031 16.8 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RasGEF PF00617.14 CEH16780.1 - 6.1e-48 163.0 0.0 1e-47 162.2 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEH16780.1 - 9.3e-15 54.6 0.1 2.3e-14 53.3 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Radical_SAM PF04055.16 CEH16781.1 - 1.1e-16 61.5 0.1 2.6e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CEH16781.1 - 3.5e-11 42.9 0.0 9.8e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEH16781.1 - 0.03 14.4 0.1 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RRM_1 PF00076.17 CEH16782.1 - 3.4e-26 90.6 0.0 1.3e-09 37.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH16782.1 - 3e-22 78.3 0.0 2.4e-09 37.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH16782.1 - 2.4e-10 40.0 0.0 2e-05 24.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAS2 PF02187.12 CEH16784.1 - 7.8e-06 25.5 0.2 2.3e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain DUF342 PF03961.8 CEH16784.1 - 0.054 11.9 0.0 0.21 9.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2935 PF11155.3 CEH16784.1 - 0.23 11.5 2.7 6 6.9 0.2 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Syntaxin PF00804.20 CEH16784.1 - 1.6 8.9 12.7 8.8 6.5 0.0 4.4 4 1 1 5 5 5 0 Syntaxin Methyltransf_11 PF08241.7 CEH16785.1 - 4.6e-08 33.4 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH16785.1 - 5.7e-08 32.6 0.0 8.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH16785.1 - 6.4e-07 29.9 0.0 2.2e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH16785.1 - 1.1e-06 28.9 0.0 2.8e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH16785.1 - 0.00019 21.0 0.0 0.0009 18.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH16785.1 - 0.023 15.0 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CEH16785.1 - 0.025 14.6 0.1 0.46 10.5 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 CEH16785.1 - 0.032 13.6 0.2 0.053 12.9 0.1 1.4 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 CEH16785.1 - 0.057 14.2 0.0 0.14 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ecl1 PF12855.2 CEH16786.1 - 0.00019 20.6 0.3 0.00035 19.8 0.2 1.4 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 CEH16786.1 - 0.034 14.0 1.8 0.066 13.1 1.2 1.4 1 0 0 1 1 1 0 MYND finger DUF2116 PF09889.4 CEH16786.1 - 0.085 12.6 1.1 0.19 11.5 0.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RRM_1 PF00076.17 CEH16787.1 - 6e-34 115.5 0.0 7.8e-16 57.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH16787.1 - 1.5e-29 101.7 0.0 2.1e-13 50.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH16787.1 - 3.7e-14 52.3 0.0 5.1e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pam16 PF03656.8 CEH16788.1 - 1.5e-20 73.2 0.2 2.3e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 Pam16 Peptidase_S58 PF03576.9 CEH16788.1 - 0.2 10.7 5.3 0.27 10.3 1.9 2.1 2 0 0 2 2 2 0 Peptidase family S58 BTB PF00651.26 CEH16789.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Abhydrolase_6 PF12697.2 CEH16790.1 - 3.9e-08 33.4 1.6 6.9e-08 32.6 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH16790.1 - 2.1e-07 30.8 0.0 5.4e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH16790.1 - 0.041 13.4 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 CEH16790.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Las1 PF04031.8 CEH16791.1 - 1.2e-45 154.8 0.4 3.1e-45 153.6 0.1 1.8 2 0 0 2 2 2 1 Las1-like DER1 PF04511.10 CEH16791.1 - 1.5e-36 125.8 2.0 2.1e-36 125.2 1.4 1.1 1 0 0 1 1 1 1 Der1-like family GCFC PF07842.7 CEH16792.1 - 1.5e-72 244.2 10.8 2.2e-72 243.7 7.5 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 CEH16792.1 - 1.7e-09 37.7 7.7 1.7e-09 37.7 5.3 3.7 4 1 0 4 4 4 1 Tuftelin interacting protein N terminal G-patch PF01585.18 CEH16792.1 - 2.2e-07 30.5 3.7 2.2e-07 30.5 2.6 2.3 3 0 0 3 3 3 1 G-patch domain Lyase_1 PF00206.15 CEH16793.1 - 4.6e-118 393.9 0.0 6e-118 393.5 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CEH16793.1 - 3e-19 68.8 0.7 1.2e-18 66.8 0.0 2.3 2 0 0 2 2 2 1 Fumarase C C-terminus ADH_N PF08240.7 CEH16793.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 CEH16794.1 - 6.5e-32 110.5 33.6 1e-31 109.9 23.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2905 PF11146.3 CEH16794.1 - 0.089 12.7 5.3 3.6 7.5 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) BDV_P24 PF06595.6 CEH16795.1 - 0.1 12.3 0.7 0.19 11.5 0.5 1.4 1 0 0 1 1 1 0 Borna disease virus P24 protein Peptidase_M56 PF05569.6 CEH16795.1 - 1.3 7.9 6.0 0.23 10.4 0.2 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 Pro_isomerase PF00160.16 CEH16797.1 - 2.7e-45 154.3 0.1 3.7e-45 153.8 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CD52 PF15116.1 CEH16797.1 - 0.15 11.8 1.5 0.35 10.7 1.1 1.6 1 0 0 1 1 1 0 CAMPATH-1 antigen Pkinase PF00069.20 CEH16798.1 - 1.9e-60 204.2 0.0 2.4e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH16798.1 - 3.8e-37 127.7 0.0 1.3e-34 119.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEH16798.1 - 0.00029 19.9 0.0 0.00078 18.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CEH16798.1 - 0.026 13.3 0.3 0.042 12.6 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 CEH16798.1 - 0.065 12.9 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.20 CEH16801.1 - 1e-15 58.0 0.1 1e-12 48.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CEH16801.1 - 4.4e-07 29.9 0.0 5.3e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH16801.1 - 4.6e-07 29.6 0.1 2.2e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 KR domain SRF-TF PF00319.13 CEH16802.1 - 1.8e-21 75.0 0.1 4e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Cut12 PF11500.3 CEH16803.1 - 0.0033 17.1 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Spindle pole body formation-associated protein PPR_3 PF13812.1 CEH16803.1 - 0.59 10.5 2.8 9.4 6.8 0.0 4.4 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Cutinase PF01083.17 CEH16804.1 - 7e-14 51.9 0.0 8.8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Cutinase DUF883 PF05957.8 CEH16805.1 - 3.2e-05 24.2 32.0 0.075 13.4 3.0 4.2 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 CEH16805.1 - 0.17 12.2 17.4 1.5e+04 -3.8 12.0 4.0 1 1 0 1 1 1 0 YtxH-like protein Apolipoprotein PF01442.13 CEH16805.1 - 0.68 9.4 16.9 3.2 7.1 11.7 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain BAR PF03114.13 CEH16805.1 - 5.9 6.3 9.2 0.28 10.6 0.3 2.2 1 1 1 2 2 2 0 BAR domain HAUS-augmin3 PF14932.1 CEH16805.1 - 6.8 5.7 16.8 0.26 10.4 3.5 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 GMC_oxred_N PF00732.14 CEH16806.1 - 5.3e-41 140.6 0.0 3.6e-40 137.9 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CEH16806.1 - 6.5e-26 91.3 0.0 1.2e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 CEH16806.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thr_synth_N PF14821.1 CEH16807.1 - 2.3e-24 85.2 0.0 6.4e-24 83.7 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 CEH16807.1 - 4.6e-23 81.9 0.1 2.2e-22 79.6 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_2d PF01409.15 CEH16808.1 - 6.1e-45 153.3 0.0 8.4e-25 87.3 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CEH16808.1 - 6e-24 84.0 0.0 3.7e-23 81.4 0.0 2.2 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain DEAD PF00270.24 CEH16809.1 - 4.3e-42 143.4 0.0 5e-41 140.0 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH16809.1 - 4.4e-21 74.5 0.0 1.5e-20 72.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC PF00098.18 CEH16809.1 - 0.0057 16.5 1.0 0.01 15.7 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CEH16809.1 - 0.009 15.6 1.3 0.019 14.6 0.6 1.8 2 0 0 2 2 2 1 Zinc knuckle DUF2285 PF10074.4 CEH16809.1 - 0.1 12.9 1.5 0.29 11.4 1.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) Helicase_C_2 PF13307.1 CEH16809.1 - 0.3 11.0 0.0 0.3 11.0 0.0 2.6 2 1 1 3 3 3 0 Helicase C-terminal domain PP2C PF00481.16 CEH16810.1 - 9.5e-77 257.8 0.0 2.1e-76 256.7 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Exo_endo_phos PF03372.18 CEH16811.1 - 3e-21 76.5 0.0 4.2e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DASH_Hsk3 PF08227.6 CEH16812.1 - 1.6e-13 50.5 1.4 2.2e-13 50.1 0.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Flg_bb_rod PF00460.15 CEH16812.1 - 0.044 13.4 2.4 0.11 12.2 1.7 1.7 1 0 0 1 1 1 0 Flagella basal body rod protein HWE_HK PF07536.9 CEH16812.1 - 0.086 13.2 0.6 0.15 12.5 0.4 1.5 1 1 0 1 1 1 0 HWE histidine kinase CH PF00307.26 CEH16814.1 - 3.5e-35 120.3 0.0 9.7e-20 70.6 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 CEH16814.1 - 8.4e-21 73.7 0.3 2.6e-20 72.1 0.0 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 CEH16814.1 - 1.8e-09 37.1 0.1 2.4e-06 27.0 0.0 2.8 2 1 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.16 CEH16814.1 - 0.0025 18.0 4.0 1 9.6 0.1 2.8 2 0 0 2 2 2 2 Spectrin repeat EF-hand_6 PF13405.1 CEH16814.1 - 0.0061 16.3 0.0 0.024 14.4 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain GDA1_CD39 PF01150.12 CEH16815.1 - 1.6e-84 283.9 0.0 2.1e-84 283.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family WD40 PF00400.27 CEH16817.1 - 6.1e-30 102.0 0.2 4.7e-05 23.1 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Gmad1 PF10647.4 CEH16817.1 - 1.7e-10 40.6 0.0 2e-08 33.9 0.0 2.2 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.6 CEH16817.1 - 0.0039 16.9 1.2 12 5.5 0.1 3.9 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A CBF PF03914.12 CEH16818.1 - 8e-35 119.7 1.3 1.4e-34 118.8 0.0 2.1 2 0 0 2 2 2 1 CBF/Mak21 family DUF2057 PF09829.4 CEH16818.1 - 0.2 11.2 1.4 0.47 10.0 1.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) HEAT PF02985.17 CEH16818.1 - 0.65 10.2 3.1 1.1 9.4 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat RRP7 PF12923.2 CEH16819.1 - 2.7 8.0 7.2 1.2 9.1 0.9 2.4 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Kei1 PF08552.6 CEH16821.1 - 2.6e-40 138.0 0.8 3.8e-40 137.5 0.6 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Sdh_cyt PF01127.17 CEH16821.1 - 0.044 13.6 0.0 0.044 13.6 0.0 2.3 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ribosomal_S24e PF01282.14 CEH16822.1 - 1.1e-31 108.4 0.0 1.1e-31 108.4 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S24e BolA PF01722.13 CEH16822.1 - 0.087 12.7 0.2 10 6.1 0.0 2.4 2 1 0 2 2 2 0 BolA-like protein Ribosomal_S9 PF00380.14 CEH16823.1 - 2.7e-38 130.9 0.9 3e-38 130.7 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Rpn3_C PF08375.6 CEH16824.1 - 1.2e-23 83.2 1.0 1.2e-23 83.2 0.7 2.7 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 CEH16824.1 - 7.9e-22 77.5 0.1 2.3e-21 76.0 0.1 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 CEH16824.1 - 0.025 14.3 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 CEH16824.1 - 0.055 13.3 0.5 0.17 11.9 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_S49_N PF08496.5 CEH16824.1 - 1.9 8.3 5.6 3.4 7.4 3.2 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TIP49 PF06068.8 CEH16825.1 - 2.5e-180 599.4 0.1 3.1e-180 599.1 0.1 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CEH16825.1 - 7.1e-11 42.4 0.1 1e-06 28.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CEH16825.1 - 5.2e-10 38.7 0.4 7.6e-06 25.1 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CEH16825.1 - 1.9e-07 31.2 0.0 0.00043 20.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CEH16825.1 - 5.4e-06 26.5 0.3 0.051 13.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CEH16825.1 - 1.7e-05 24.6 0.1 0.009 15.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CEH16825.1 - 5.2e-05 22.9 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CEH16825.1 - 0.00027 20.3 0.0 0.00052 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CEH16825.1 - 0.00047 20.1 0.1 0.00092 19.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CEH16825.1 - 0.0026 17.2 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 CEH16825.1 - 0.0029 17.0 0.1 0.0086 15.5 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CEH16825.1 - 0.0048 16.7 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CEH16825.1 - 0.0074 15.4 0.1 0.33 10.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CEH16825.1 - 0.0082 15.8 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 CEH16825.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 CEH16825.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NTPase_1 PF03266.10 CEH16825.1 - 0.021 14.5 0.1 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 NTPase UPF0079 PF02367.12 CEH16825.1 - 0.041 13.4 0.1 0.11 12.1 0.0 1.6 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 CEH16825.1 - 0.08 13.7 0.1 0.25 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PPP4R2 PF09184.6 CEH16826.1 - 2.1e-08 34.0 2.9 3.8e-08 33.2 0.0 2.7 3 0 0 3 3 3 1 PPP4R2 HTH_36 PF13730.1 CEH16826.1 - 0.11 12.6 0.2 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Trm112p PF03966.11 CEH16827.1 - 2.6e-17 62.9 0.0 3.5e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein PhnA_Zn_Ribbon PF08274.7 CEH16827.1 - 0.063 13.0 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon RIO1 PF01163.17 CEH16829.1 - 1.7e-38 131.8 0.5 2e-26 92.5 0.0 2.5 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 CEH16829.1 - 9.7e-19 67.2 0.0 3e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 CEH16829.1 - 5.1e-07 29.6 1.0 0.00052 19.8 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CEH16829.1 - 0.00015 20.8 0.0 0.0016 17.5 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PHO4 PF01384.15 CEH16831.1 - 2.7e-95 318.7 22.3 3.2e-95 318.5 15.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family URO-D PF01208.12 CEH16832.1 - 2.1e-130 434.6 0.0 2.4e-130 434.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) APC10 PF03256.11 CEH16833.1 - 3.3e-44 150.8 1.3 9.3e-44 149.3 0.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Prenyltransf PF01255.14 CEH16844.1 - 2e-70 236.3 0.0 2.4e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Fcf1 PF04900.7 CEH16845.1 - 6.6e-21 74.3 1.3 1.3e-20 73.3 0.9 1.5 1 0 0 1 1 1 1 Fcf1 SR-25 PF10500.4 CEH16845.1 - 0.25 10.7 6.4 0.49 9.8 4.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2404 PF10296.4 CEH16847.1 - 3.8e-28 97.4 0.0 6.5e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Phosphodiest PF01663.17 CEH16848.1 - 2.5e-08 33.6 0.8 1.2e-07 31.3 0.7 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Mito_fiss_reg PF05308.6 CEH16848.1 - 1.1 8.6 30.5 0.33 10.2 0.9 3.8 4 0 0 4 4 4 0 Mitochondrial fission regulator NUC153 PF08159.7 CEH16849.1 - 9.6e-10 37.8 7.3 2.2e-09 36.7 0.9 3.1 3 0 0 3 3 3 2 NUC153 domain WBS_methylT PF12589.3 CEH16850.1 - 3.9e-18 65.7 8.5 3.9e-18 65.7 5.9 1.7 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CEH16850.1 - 4e-12 46.4 0.0 7.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH16850.1 - 3.5e-08 33.3 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH16850.1 - 1.6e-07 31.7 0.0 3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH16850.1 - 2.5e-07 30.4 0.0 3.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH16850.1 - 4.6e-06 27.1 0.0 8.3e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH16850.1 - 3.3e-05 24.1 0.0 6.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH16850.1 - 0.00016 21.6 0.1 0.00031 20.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CEH16850.1 - 0.0057 16.1 0.3 0.024 14.1 0.0 2.0 2 1 0 2 2 2 1 DNA methylase PCMT PF01135.14 CEH16850.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 CEH16850.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ank_4 PF13637.1 CEH16850.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF3941 PF13081.1 CEH16853.1 - 2.4 8.2 5.5 3.9 7.5 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) EF-hand_8 PF13833.1 CEH16856.1 - 0.00061 19.3 1.1 0.91 9.1 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CEH16856.1 - 0.00063 18.8 2.1 0.074 12.3 0.1 2.7 2 0 0 2 2 2 2 EF hand PAN_4 PF14295.1 CEH16856.1 - 0.0025 17.4 0.2 0.0025 17.4 0.1 2.5 4 0 0 4 4 4 1 PAN domain EF-hand_6 PF13405.1 CEH16856.1 - 0.0032 17.2 3.2 0.1 12.5 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain PAN_1 PF00024.21 CEH16856.1 - 0.0039 16.9 2.3 0.0039 16.9 1.6 2.3 1 1 1 2 2 2 1 PAN domain PAN_2 PF08276.6 CEH16856.1 - 0.0045 16.7 2.1 0.0045 16.7 1.5 2.3 2 0 0 2 2 2 1 PAN-like domain EF-hand_5 PF13202.1 CEH16856.1 - 0.3 10.5 1.9 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 EF hand Glyco_hydro_18 PF00704.23 CEH16857.1 - 2.4e-83 280.4 0.7 2.8e-83 280.2 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 CEH16857.1 - 5.6e-12 45.4 20.9 1.5e-11 44.0 14.5 1.8 1 0 0 1 1 1 1 Chitin recognition protein DUF4159 PF13709.1 CEH16857.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Ank_2 PF12796.2 CEH16858.1 - 9.1e-15 54.7 0.2 1e-07 32.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CEH16858.1 - 3e-08 33.0 2.4 0.0023 17.6 0.0 3.9 5 1 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 CEH16858.1 - 1.2e-06 28.1 2.0 0.054 13.7 0.0 4.9 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CEH16858.1 - 0.00053 20.1 0.5 1.8 8.9 0.0 4.5 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CEH16858.1 - 0.00068 20.0 0.0 0.32 11.5 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) LysM PF01476.15 CEH16859.1 - 6e-47 157.2 2.1 4.6e-10 39.2 0.0 6.2 6 0 0 6 6 6 5 LysM domain TPR_2 PF07719.12 CEH16867.1 - 0.016 15.1 1.1 0.058 13.3 0.8 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEH16867.1 - 0.034 13.9 0.1 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEH16867.1 - 0.045 13.6 1.5 0.81 9.6 0.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEH16867.1 - 0.082 12.8 1.5 0.18 11.6 0.4 2.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MerR-DNA-bind PF09278.6 CEH16867.1 - 0.13 12.6 5.5 0.37 11.2 0.1 3.4 3 0 0 3 3 3 0 MerR, DNA binding Paf67 PF10255.4 CEH16867.1 - 0.23 10.2 0.1 0.4 9.4 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_6 PF13174.1 CEH16867.1 - 5 7.8 6.0 2.7 8.6 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TFIIS_C PF01096.13 CEH16868.1 - 2.6e-16 58.9 1.8 2.6e-16 58.9 1.3 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CEH16868.1 - 1.1e-05 25.0 7.3 0.00027 20.5 0.0 3.0 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 CEH16868.1 - 3.4e-05 23.5 6.5 0.0078 16.0 0.0 2.9 2 1 1 3 3 3 1 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 CEH16868.1 - 0.00011 21.7 5.1 0.01 15.4 0.0 2.8 2 1 0 2 2 2 1 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.7 CEH16868.1 - 0.00021 20.5 13.1 0.07 12.4 2.0 3.0 2 2 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 CEH16868.1 - 0.0011 18.0 13.8 0.16 11.1 0.2 3.7 3 1 0 3 3 3 2 zinc-ribbon domain Lar_restr_allev PF14354.1 CEH16868.1 - 0.0054 16.9 10.4 0.0068 16.6 0.3 2.9 2 1 0 2 2 2 1 Restriction alleviation protein Lar DNA_ligase_ZBD PF03119.11 CEH16868.1 - 0.0097 15.5 0.8 0.0097 15.5 0.5 3.2 3 0 0 3 3 3 1 NAD-dependent DNA ligase C4 zinc finger domain PhnA_Zn_Ribbon PF08274.7 CEH16868.1 - 0.016 14.9 5.4 3.9 7.3 1.6 3.3 2 1 0 2 2 2 0 PhnA Zinc-Ribbon IBR PF01485.16 CEH16868.1 - 0.022 14.6 4.3 4.2 7.3 1.4 2.5 2 1 0 2 2 2 0 IBR domain Terminase_GpA PF05876.7 CEH16868.1 - 0.03 12.6 0.6 0.052 11.9 0.4 1.4 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Baculo_LEF5_C PF11792.3 CEH16868.1 - 0.037 13.4 0.5 0.18 11.2 0.4 2.2 1 1 1 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-H2C2_2 PF13465.1 CEH16868.1 - 0.038 14.2 0.2 0.038 14.2 0.1 3.4 3 1 1 4 4 3 0 Zinc-finger double domain zf-TFIIB PF13453.1 CEH16868.1 - 0.039 13.1 1.1 0.039 13.1 0.8 3.0 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-RING_3 PF14369.1 CEH16868.1 - 0.041 13.8 10.3 5.9 6.9 0.0 4.0 3 1 1 4 4 4 0 zinc-finger Prok-RING_1 PF14446.1 CEH16868.1 - 0.043 13.5 8.5 0.14 11.9 0.7 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-NADH-PPase PF09297.6 CEH16868.1 - 0.046 13.2 11.3 2.5 7.7 2.1 3.5 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Zn_ribbon_recom PF13408.1 CEH16868.1 - 0.06 13.6 6.7 0.89 9.8 0.7 3.0 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain DUF164 PF02591.10 CEH16868.1 - 0.062 13.1 4.0 19 5.1 0.0 3.9 4 0 0 4 4 4 0 Putative zinc ribbon domain zinc_ribbon_2 PF13240.1 CEH16868.1 - 0.063 12.7 14.6 0.99 8.9 1.9 3.5 4 0 0 4 4 3 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 CEH16868.1 - 0.083 12.2 0.5 0.083 12.2 0.3 1.6 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Rubredoxin PF00301.15 CEH16868.1 - 0.087 12.7 6.5 24 4.8 0.0 4.2 4 0 0 4 4 4 0 Rubredoxin CpXC PF14353.1 CEH16868.1 - 0.13 12.1 7.1 45 4.0 0.0 3.8 2 1 2 4 4 4 0 CpXC protein zinc_ribbon_5 PF13719.1 CEH16868.1 - 0.14 11.7 13.6 7.4 6.2 0.8 4.0 3 1 0 3 3 3 0 zinc-ribbon domain Desulfoferrod_N PF06397.7 CEH16868.1 - 0.15 11.4 3.9 1.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-RING_2 PF13639.1 CEH16868.1 - 0.19 11.5 4.8 2.3 8.1 1.8 2.8 2 1 0 2 2 2 0 Ring finger domain Nop10p PF04135.7 CEH16868.1 - 0.2 11.4 2.6 1.4 8.7 0.0 3.1 4 0 0 4 4 3 0 Nucleolar RNA-binding protein, Nop10p family HypA PF01155.14 CEH16868.1 - 0.25 11.0 6.6 3.5 7.3 2.0 2.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family SprT-like PF10263.4 CEH16868.1 - 0.25 10.9 1.9 0.5 10.0 0.4 1.9 1 1 0 2 2 2 0 SprT-like family Zn-ribbon_8 PF09723.5 CEH16868.1 - 0.33 10.9 16.9 2.5 8.1 0.4 4.2 2 2 1 4 4 4 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 CEH16868.1 - 0.34 10.6 14.6 8.8 6.1 0.1 4.1 3 1 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CEH16868.1 - 0.35 10.7 13.1 0.44 10.3 1.7 3.7 2 2 1 3 3 3 0 Transposase zinc-ribbon domain DNA_RNApol_7kD PF03604.8 CEH16868.1 - 0.37 10.2 10.7 0.13 11.7 0.6 3.3 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit PolC_DP2 PF03833.8 CEH16868.1 - 0.38 8.3 2.4 0.26 8.8 0.5 1.5 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 DUF2072 PF09845.4 CEH16868.1 - 0.81 9.6 0.1 0.81 9.6 0.1 2.7 2 2 1 4 4 3 0 Zn-ribbon containing protein (DUF2072) DUF3797 PF12677.2 CEH16868.1 - 0.85 9.2 7.1 0.46 10.1 0.3 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3797) Nudix_N_2 PF14803.1 CEH16868.1 - 0.91 9.2 12.9 4.8 6.9 2.5 3.9 2 2 1 3 3 3 0 Nudix N-terminal C1_4 PF07975.7 CEH16868.1 - 0.98 9.4 5.1 19 5.3 1.4 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain DnaJ_CXXCXGXG PF00684.14 CEH16868.1 - 1.3 9.0 5.4 16 5.6 1.4 2.6 2 1 0 2 2 2 0 DnaJ central domain zf-ISL3 PF14690.1 CEH16868.1 - 1.3 9.0 11.4 6.7 6.8 0.1 4.0 3 1 1 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2387 PF09526.5 CEH16868.1 - 1.5 8.7 7.1 4.1 7.3 0.3 2.7 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-FPG_IleRS PF06827.9 CEH16868.1 - 2.1 8.0 11.3 2.9 7.6 0.7 3.4 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-AN1 PF01428.11 CEH16868.1 - 2.4 8.1 5.4 63 3.5 0.1 3.2 3 1 0 3 3 3 0 AN1-like Zinc finger Cys_rich_KTR PF14205.1 CEH16868.1 - 2.5 7.6 6.1 55 3.3 0.1 3.6 4 0 0 4 4 4 0 Cysteine-rich KTR PHD PF00628.24 CEH16868.1 - 2.7 7.7 7.6 3.9 7.2 0.3 2.7 2 1 1 3 3 3 0 PHD-finger zf-LITAF-like PF10601.4 CEH16868.1 - 3 7.7 5.5 24 4.8 0.1 3.5 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain Ribosomal_S27e PF01667.12 CEH16868.1 - 5.4 6.6 10.0 2.8 7.5 0.1 3.3 3 1 1 4 4 3 0 Ribosomal protein S27 Ogr_Delta PF04606.7 CEH16868.1 - 5.6 6.6 10.1 9.8 5.9 2.9 3.1 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger NOB1_Zn_bind PF08772.6 CEH16868.1 - 6 6.7 11.0 3.5 7.5 0.8 3.0 2 2 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-C4_Topoisom PF01396.14 CEH16868.1 - 8.7 5.9 15.3 18 4.9 0.1 3.4 3 1 0 3 3 2 0 Topoisomerase DNA binding C4 zinc finger VP_N-CPKC PF11475.3 CEH16868.1 - 8.9 5.9 7.2 13 5.3 0.1 3.2 3 0 0 3 3 3 0 Virion protein N terminal domain Methyltransf_23 PF13489.1 CEH16869.1 - 5.7e-14 52.1 0.0 8.7e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CEH16869.1 - 6.7e-08 31.5 0.0 8.8e-08 31.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 CEH16869.1 - 3.4e-07 30.6 0.0 5.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH16869.1 - 8.5e-06 26.3 0.0 1.3e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH16869.1 - 2.3e-05 24.7 0.0 3.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH16869.1 - 0.00071 19.1 0.0 0.0035 16.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain zf-Apc11 PF12861.2 CEH16870.1 - 2.6e-30 104.1 7.1 3.3e-30 103.7 4.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CEH16870.1 - 5e-25 87.4 4.4 6.3e-25 87.0 3.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CEH16870.1 - 4.9e-08 32.6 11.0 1.8e-07 30.8 7.6 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CEH16870.1 - 1.2e-05 24.8 4.5 3.1e-05 23.5 3.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH16870.1 - 0.00017 21.5 7.3 0.0017 18.3 5.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH16870.1 - 0.00067 19.3 9.7 0.0048 16.5 7.0 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEH16870.1 - 0.0057 16.2 8.3 0.026 14.1 5.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CEH16870.1 - 0.033 14.1 10.5 0.13 12.2 7.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_3 PF14369.1 CEH16870.1 - 0.066 13.2 1.3 7.5 6.6 0.0 2.7 3 0 0 3 3 3 0 zinc-finger zf-C3HC4_4 PF15227.1 CEH16870.1 - 0.086 12.7 0.9 0.086 12.7 0.6 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 CEH16870.1 - 0.096 12.2 3.1 0.16 11.5 2.1 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CEH16870.1 - 0.37 10.5 3.8 0.46 10.2 1.8 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CEH16870.1 - 1 8.9 8.3 1.2 8.7 3.5 2.4 1 1 2 3 3 3 0 RING/Ubox like zinc-binding domain PHD PF00628.24 CEH16870.1 - 2.4 7.8 11.5 16 5.2 8.0 2.1 1 1 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 CEH16870.1 - 3 7.8 6.8 9.6 6.2 4.8 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CEH16870.1 - 4.5 7.4 8.2 23 5.1 5.6 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain RINGv PF12906.2 CEH16870.1 - 4.7 7.3 8.7 22 5.2 6.0 2.2 1 1 0 1 1 1 0 RING-variant domain Steroid_dh PF02544.11 CEH16871.1 - 4.6e-34 117.3 0.3 6.5e-34 116.8 0.2 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CEH16871.1 - 3.2e-05 23.3 0.2 4.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) YukD PF08817.5 CEH16871.1 - 9.5e-05 22.8 0.1 0.00017 22.0 0.1 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PEMT PF04191.8 CEH16871.1 - 0.00095 19.2 0.2 0.0024 17.9 0.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ubiquitin PF00240.18 CEH16871.1 - 0.0054 16.0 0.3 0.01 15.1 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family UAE_UbL PF14732.1 CEH16871.1 - 0.0066 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UN_NPL4 PF11543.3 CEH16871.1 - 0.027 14.7 0.1 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 ICMT PF04140.9 CEH16871.1 - 0.042 14.0 0.9 0.078 13.1 0.0 1.9 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TMA7 PF09072.5 CEH16873.1 - 4.3e-17 62.3 17.7 4.6e-17 62.2 12.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Arrestin_N PF00339.24 CEH16874.1 - 1.1e-05 25.3 0.0 3.5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CEH16874.1 - 0.0005 20.1 0.0 0.0016 18.5 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Asp-B-Hydro_N PF05279.6 CEH16874.1 - 4.2 7.1 9.5 9.4 6.0 6.6 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AMP-binding PF00501.23 CEH16876.1 - 2.4e-68 230.4 0.0 2.8e-33 114.9 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CEH16876.1 - 4.9e-08 33.8 0.1 1.2e-07 32.5 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UBX PF00789.15 CEH16877.1 - 4.7e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF4407 PF14362.1 CEH16877.1 - 2 7.2 17.2 2.7 6.8 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC27 PF09507.5 CEH16877.1 - 2.4 7.2 23.7 3.4 6.7 16.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Abhydrolase_4 PF08386.5 CEH16878.1 - 1.3e-13 50.7 0.0 3.6e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 CEH16878.1 - 1.2e-12 47.9 1.9 2e-10 40.6 1.3 3.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEH16878.1 - 3.2e-05 23.9 10.6 0.0042 17.0 7.3 2.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Gemini_mov PF01708.11 CEH16878.1 - 0.075 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein Thioredoxin PF00085.15 CEH16879.1 - 1.5e-57 191.6 0.1 3.3e-28 97.3 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CEH16879.1 - 4.5e-18 65.4 3.9 3.2e-09 36.9 0.0 3.7 3 2 0 3 3 3 2 Thioredoxin-like domain ERp29 PF07749.7 CEH16879.1 - 8.4e-17 61.5 0.1 8.4e-17 61.5 0.1 3.4 4 0 0 4 4 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_8 PF13905.1 CEH16879.1 - 2.3e-12 46.8 0.3 0.00091 19.3 0.1 4.2 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CEH16879.1 - 2e-10 40.5 0.1 6.1e-06 26.1 0.1 2.8 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 CEH16879.1 - 2.9e-07 30.2 0.2 0.0045 16.6 0.0 2.7 2 1 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 CEH16879.1 - 1.4e-06 27.9 0.2 0.001 18.6 0.0 2.5 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.8 CEH16879.1 - 1.5e-06 28.1 0.8 0.031 14.2 0.0 2.5 2 0 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_6 PF13848.1 CEH16879.1 - 6.2e-05 22.8 6.1 0.0024 17.6 0.1 3.6 3 1 1 4 4 4 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 CEH16879.1 - 0.00014 21.8 6.0 0.44 10.5 0.1 3.7 3 1 1 4 4 4 2 Thioredoxin TraF PF13728.1 CEH16879.1 - 0.00037 20.0 7.3 0.02 14.3 0.0 3.6 3 1 1 4 4 4 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 CEH16879.1 - 0.00065 19.2 3.7 0.023 14.2 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.1 CEH16879.1 - 0.00075 19.2 1.2 0.43 10.4 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin domain HyaE PF07449.6 CEH16879.1 - 0.0025 17.6 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Mu-like_Com PF10122.4 CEH16879.1 - 0.063 12.3 0.8 8.3 5.5 0.1 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com DDE_Tnp_1_2 PF13586.1 CEH16879.1 - 0.082 13.1 0.0 8.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Transposase DDE domain Phasin PF05597.6 CEH16879.1 - 0.17 11.6 7.6 0.22 11.2 4.6 1.7 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1319 PF07028.6 CEH16879.1 - 0.18 11.9 4.8 0.49 10.6 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) YtxH PF12732.2 CEH16879.1 - 4.3 7.7 10.1 2.3 8.6 3.3 2.6 2 0 0 2 2 2 0 YtxH-like protein Sec63 PF02889.11 CEH16880.1 - 5.3e-178 590.9 0.0 1.4e-93 313.6 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CEH16880.1 - 5.4e-47 159.4 0.0 2.5e-28 98.6 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 CEH16880.1 - 1.6e-15 57.4 0.0 9.3e-10 38.6 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CEH16880.1 - 3.5e-09 36.3 0.0 1e-07 31.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.11 CEH16880.1 - 0.05 12.8 0.1 1.4 8.0 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein RHD3 PF05879.7 CEH16881.1 - 1.3e-235 783.7 0.0 1.6e-235 783.4 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 CEH16881.1 - 0.00012 21.9 0.0 0.00039 20.2 0.0 1.9 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CEH16881.1 - 0.00021 21.1 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.14 CEH16881.1 - 0.00026 20.1 0.0 0.00048 19.2 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Miro PF08477.8 CEH16881.1 - 0.00057 20.3 0.0 0.0015 19.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 CEH16881.1 - 0.0046 16.9 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF3254 PF11630.3 CEH16882.1 - 0.049 13.6 1.0 0.052 13.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) DUF3602 PF12223.3 CEH16883.1 - 7.5e-13 48.6 27.2 0.00031 21.0 2.7 3.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Glyoxal_oxid_N PF07250.6 CEH16884.1 - 6e-33 113.9 0.0 1e-31 109.9 0.0 2.8 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CEH16884.1 - 6.2e-17 61.5 0.1 1.4e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Shisa PF13908.1 CEH16884.1 - 0.0097 16.0 0.0 0.044 13.9 0.0 2.2 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Kelch_4 PF13418.1 CEH16884.1 - 0.028 14.1 9.7 1.3 8.8 0.1 5.2 5 0 0 5 5 5 0 Galactose oxidase, central domain SKG6 PF08693.5 CEH16884.1 - 0.11 11.8 7.3 0.24 10.7 5.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 CEH16884.1 - 0.26 10.8 2.1 0.52 9.9 1.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1401 PF07180.6 CEH16885.1 - 0.13 11.9 0.7 0.22 11.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1401) 6PF2K PF01591.13 CEH16886.1 - 1.7e-63 213.6 0.0 2.2e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CEH16886.1 - 1.3e-18 67.5 0.0 2.4e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CEH16886.1 - 3.9e-05 23.5 0.0 7.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEH16886.1 - 0.0043 17.8 0.1 0.016 16.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEH16886.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 CEH16886.1 - 0.094 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Linker_histone PF00538.14 CEH16888.1 - 8e-16 57.8 0.2 8e-16 57.8 0.1 1.8 2 1 0 2 2 2 1 linker histone H1 and H5 family Mrr_cat PF04471.7 CEH16888.1 - 0.035 13.9 0.1 0.035 13.9 0.1 1.8 1 1 1 2 2 2 0 Restriction endonuclease Presenilin PF01080.12 CEH16888.1 - 1.2 7.9 2.8 1.1 7.9 2.0 1.2 1 0 0 1 1 1 0 Presenilin Herpes_UL17 PF04559.7 CEH16888.1 - 5.4 5.4 7.3 6.8 5.1 5.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein SnoaL PF07366.7 CEH16889.1 - 5.5e-23 80.9 0.0 6.7e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 CEH16889.1 - 2.9e-08 34.0 0.0 4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain VHS PF00790.14 CEH16890.1 - 3.5e-40 136.8 0.0 8.2e-40 135.6 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 CEH16890.1 - 4e-21 74.8 0.1 9.5e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 GAT domain DIE2_ALG10 PF04922.7 CEH16891.1 - 2.6e-91 306.5 12.7 8.6e-70 235.6 7.4 2.1 2 0 0 2 2 2 2 DIE2/ALG10 family FA_desaturase PF00487.19 CEH16892.1 - 1.7e-17 63.6 25.9 2.8e-17 63.0 18.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CEH16892.1 - 1.6e-15 56.6 0.0 3.1e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cellulase PF00150.13 CEH16896.1 - 2e-07 30.5 0.0 3.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) S1-P1_nuclease PF02265.11 CEH16897.1 - 3.4e-43 148.0 0.1 5e-38 131.1 0.9 2.3 2 0 0 2 2 2 2 S1/P1 Nuclease Mem_trans PF03547.13 CEH16897.1 - 4.2e-34 117.4 8.0 3.3e-30 104.6 0.7 2.9 2 1 0 2 2 2 2 Membrane transport protein Snf7 PF03357.16 CEH16898.1 - 5.6e-31 107.2 16.9 5.6e-31 107.2 11.7 1.5 1 1 0 1 1 1 1 Snf7 ACT_5 PF13710.1 CEH16898.1 - 0.0042 16.8 1.5 0.051 13.3 0.2 2.4 2 0 0 2 2 2 1 ACT domain VGLL4 PF15245.1 CEH16898.1 - 0.17 11.7 7.1 2.1 8.1 0.2 2.2 1 1 1 2 2 2 0 Transcription cofactor vestigial-like protein 4 Lectin_N PF03954.9 CEH16898.1 - 0.21 10.9 3.2 0.34 10.3 1.7 1.6 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain RNB PF00773.14 CEH16899.1 - 1.5e-51 175.6 0.0 2.5e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 RNB domain SAC3_GANP PF03399.11 CEH16900.1 - 2.5e-49 167.6 0.0 3.3e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Nup84_Nup100 PF04121.8 CEH16901.1 - 3.7e-106 355.4 10.9 6.6e-62 209.1 4.0 2.0 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 Wbp11 PF09429.5 CEH16902.1 - 3.9e-15 55.6 11.7 3.9e-15 55.6 8.1 2.6 3 0 0 3 3 3 1 WW domain binding protein 11 NpwBP PF12622.2 CEH16902.1 - 4.3e-10 39.9 14.8 4.3e-10 39.9 10.3 4.5 2 1 1 3 3 3 2 mRNA biogenesis factor TFIIE-A_C-term PF11521.3 CEH16902.1 - 2.4 8.1 7.6 10 6.1 5.2 2.1 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Rad52_Rad22 PF04098.10 CEH16903.1 - 6.9e-52 175.2 0.0 1.2e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein eIF_4EBP PF05456.6 CEH16904.1 - 2.5e-12 46.5 1.1 3.2e-11 42.9 0.2 2.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DAP_B PF07930.7 CEH16904.1 - 0.057 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 D-aminopeptidase, domain B MutL_C PF08676.6 CEH16905.1 - 1e-08 34.8 0.1 3.8e-06 26.5 0.0 3.3 2 1 0 2 2 2 1 MutL C terminal dimerisation domain DUF4549 PF15082.1 CEH16906.1 - 0.042 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Tom22 PF04281.8 CEH16907.1 - 6.1e-38 129.4 0.4 9.4e-38 128.8 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Myb_DNA-bind_6 PF13921.1 CEH16908.1 - 0.039 14.0 0.1 0.13 12.3 0.1 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sec23_trunk PF04811.10 CEH16909.1 - 2.6e-53 180.8 0.0 8.5e-53 179.2 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CEH16909.1 - 3.9e-24 84.0 0.1 7e-24 83.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CEH16909.1 - 3.4e-20 72.3 0.0 7.5e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CEH16909.1 - 5.4e-16 57.8 3.5 1.2e-15 56.7 2.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CEH16909.1 - 0.0023 17.6 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat UPF1_Zn_bind PF09416.5 CEH16910.1 - 2e-72 241.7 4.3 2e-72 241.7 3.0 1.6 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 CEH16910.1 - 2.7e-57 193.3 0.0 5.1e-57 192.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CEH16910.1 - 8.1e-55 185.9 0.7 1.1e-54 185.4 0.5 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH16910.1 - 1e-12 47.6 0.4 3.3e-12 45.9 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CEH16910.1 - 7.3e-12 45.2 0.1 8.8e-11 41.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CEH16910.1 - 7e-07 29.2 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CEH16910.1 - 3.4e-05 23.0 0.4 0.0012 17.8 0.0 2.7 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 CEH16910.1 - 0.00012 21.6 0.1 0.36 10.3 0.0 3.2 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 CEH16910.1 - 0.00033 20.3 0.0 0.00084 19.0 0.0 1.7 1 1 0 1 1 1 1 Helicase PIF1 PF05970.9 CEH16910.1 - 0.0011 17.9 0.1 0.067 12.1 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase Ribosomal_S13_N PF08069.7 CEH16910.1 - 0.013 15.2 0.0 0.039 13.7 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain KaiC PF06745.8 CEH16910.1 - 0.02 13.9 0.0 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 KaiC SRP54 PF00448.17 CEH16910.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DEAD PF00270.24 CEH16910.1 - 0.035 13.6 0.5 0.082 12.3 0.3 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.2 CEH16910.1 - 0.039 13.3 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 CEH16910.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CEH16910.1 - 0.13 11.4 0.0 0.31 10.2 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein T2SE PF00437.15 CEH16910.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 CEH16910.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 CEH16910.1 - 0.15 12.1 0.0 0.54 10.4 0.0 1.9 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 CEH16911.1 - 3e-17 63.0 0.0 5.7e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CEH16911.1 - 4.3e-13 49.2 0.0 9.4e-13 48.1 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CEH16911.1 - 7.2e-09 34.8 0.1 1.1e-07 30.9 0.1 2.3 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CEH16911.1 - 1.6e-07 31.4 0.1 1.1e-05 25.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain Rep_fac_C PF08542.6 CEH16911.1 - 7.6e-07 29.0 0.1 2.9e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_11 PF13086.1 CEH16911.1 - 1.7e-05 24.5 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEH16911.1 - 2.1e-05 24.5 0.0 0.00051 20.0 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CEH16911.1 - 2.2e-05 24.1 0.0 6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CEH16911.1 - 2.7e-05 24.0 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEH16911.1 - 6.4e-05 22.1 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus FtsK_SpoIIIE PF01580.13 CEH16911.1 - 0.00054 19.5 1.5 0.36 10.2 0.0 3.1 1 1 2 3 3 3 1 FtsK/SpoIIIE family AAA_5 PF07728.9 CEH16911.1 - 0.00068 19.3 0.0 0.0017 18.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CEH16911.1 - 0.0007 19.2 0.0 0.0018 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CEH16911.1 - 0.00099 18.3 0.1 0.028 13.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 CEH16911.1 - 0.0021 17.6 0.0 0.0064 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CEH16911.1 - 0.0062 15.9 0.1 0.021 14.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CEH16911.1 - 0.0097 15.8 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CEH16911.1 - 0.0097 15.3 0.0 0.16 11.4 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain MCM PF00493.18 CEH16911.1 - 0.011 14.5 0.0 0.1 11.3 0.0 2.2 2 1 0 2 2 2 0 MCM2/3/5 family DUF2075 PF09848.4 CEH16911.1 - 0.012 14.5 0.0 0.024 13.6 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.9 CEH16911.1 - 0.012 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_3 PF07726.6 CEH16911.1 - 0.015 14.8 0.0 0.036 13.6 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CEH16911.1 - 0.021 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 CEH16911.1 - 0.024 14.9 0.0 0.073 13.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 CEH16911.1 - 0.024 15.4 0.0 0.054 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CEH16911.1 - 0.026 14.4 0.0 0.071 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 CEH16911.1 - 0.032 13.7 0.2 0.33 10.4 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.11 CEH16911.1 - 0.041 13.1 0.1 3.6 6.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.18 CEH16911.1 - 0.11 11.2 0.0 1.6 7.4 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain Ribosomal_60s PF00428.14 CEH16912.1 - 9.4 6.7 10.5 34 4.9 4.4 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein AMP-binding PF00501.23 CEH16913.1 - 3.9e-86 289.0 0.0 5.1e-86 288.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEH16913.1 - 0.00055 20.8 0.0 0.0031 18.4 0.0 2.3 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 CEH16914.1 - 3.6e-37 128.1 0.0 5.5e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEH16914.1 - 0.036 13.2 0.0 0.072 12.2 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase zf-CCCH PF00642.19 CEH16915.1 - 1.6e-05 24.4 12.4 0.0013 18.3 0.2 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 CEH16915.1 - 0.016 15.2 7.1 0.04 13.9 4.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEH16915.1 - 0.022 14.5 7.0 0.059 13.2 4.8 1.8 1 0 0 1 1 1 0 Ring finger domain zf-CCCH_2 PF14608.1 CEH16915.1 - 0.086 12.8 6.2 0.03 14.3 0.8 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-RING_5 PF14634.1 CEH16915.1 - 0.27 11.0 6.0 0.59 9.9 4.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain CN_hydrolase PF00795.17 CEH16916.1 - 1.4e-25 89.6 0.0 2.7e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MBF1 PF08523.5 CEH16916.1 - 0.041 13.8 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Multiprotein bridging factor 1 Git3 PF11710.3 CEH16918.1 - 0.0043 16.6 1.7 0.006 16.1 1.2 1.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 CEH16919.1 - 1.4e-05 24.7 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term HEAT_2 PF13646.1 CEH16923.1 - 0.0041 17.3 0.1 0.0049 17.1 0.1 1.1 1 0 0 1 1 1 1 HEAT repeats Abhydrolase_6 PF12697.2 CEH16926.1 - 1.4e-13 51.2 1.9 3.8e-13 49.8 1.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH16926.1 - 6.1e-07 29.2 0.0 2.2e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH16926.1 - 1.6e-05 24.5 0.1 0.051 13.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.15 CEH16926.1 - 5.6e-05 23.4 0.1 0.00012 22.3 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.8 CEH16926.1 - 0.00017 21.2 0.1 0.00073 19.1 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.20 CEH16926.1 - 0.023 14.3 0.1 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Fungal_trans PF04082.13 CEH16928.1 - 7.9e-15 54.4 0.0 1.4e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH16928.1 - 0.00047 20.0 7.8 0.00077 19.3 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ceramidase_alk PF04734.8 CEH16930.1 - 7.6e-197 655.2 0.0 1.2e-108 363.7 0.0 3.9 3 1 0 3 3 3 3 Neutral/alkaline non-lysosomal ceramidase Snf7 PF03357.16 CEH16931.1 - 7.9e-17 61.1 13.3 7.9e-17 61.1 9.2 1.7 2 0 0 2 2 2 1 Snf7 DASH_Spc34 PF08657.5 CEH16931.1 - 0.1 12.2 11.2 0.038 13.6 0.9 2.3 2 0 0 2 2 2 0 DASH complex subunit Spc34 Fzo_mitofusin PF04799.8 CEH16931.1 - 0.98 8.7 7.1 0.19 11.0 1.9 2.0 2 0 0 2 2 2 0 fzo-like conserved region V_ATPase_I PF01496.14 CEH16931.1 - 3.1 5.5 10.2 4.7 4.9 7.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Catalase PF00199.14 CEH16934.1 - 6.9e-175 581.3 1.2 8e-175 581.0 0.8 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CEH16934.1 - 4.8e-17 61.5 0.8 8.3e-17 60.8 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive TOM20_plant PF06552.7 CEH16934.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 GalP_UDP_transf PF01087.17 CEH16935.1 - 2e-63 213.7 0.0 2.9e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CEH16935.1 - 3e-45 153.7 0.0 1e-44 152.0 0.0 1.9 2 1 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 CEH16935.1 - 0.036 14.5 0.0 0.087 13.3 0.0 1.6 1 0 0 1 1 1 0 HIT domain DUF3721 PF12518.3 CEH16935.1 - 0.09 12.3 1.6 9.9 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function KorB_C PF06613.6 CEH16936.1 - 0.089 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain Endotoxin_M PF00555.14 CEH16937.1 - 0.072 12.9 0.0 8.7 6.1 0.0 2.2 2 0 0 2 2 2 0 delta endotoxin TMF_TATA_bd PF12325.3 CEH16937.1 - 0.19 11.4 4.7 18 5.0 0.3 3.5 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Peroxidase_2 PF01328.12 CEH16938.1 - 2.7e-13 49.3 0.3 6.6e-13 48.0 0.2 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 Catalase PF00199.14 CEH16939.1 - 1.3e-136 455.3 3.0 1.7e-136 454.9 2.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CEH16939.1 - 5.4e-11 42.2 0.1 1.6e-10 40.7 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Scm3 PF10384.4 CEH16940.1 - 3.3e-10 39.2 0.0 1.9e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 Centromere protein Scm3 PI3Ka PF00613.15 CEH16941.1 - 1.7e-49 167.5 0.0 2.8e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CEH16941.1 - 3.2e-44 151.1 0.0 2.9e-43 148.0 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CEH16941.1 - 2.8e-26 92.0 0.0 4.5e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF1198 PF06711.6 CEH16941.1 - 0.051 13.4 0.0 0.26 11.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1198) Zn_clus PF00172.13 CEH16942.1 - 9.2e-07 28.6 12.8 1.3e-06 28.1 8.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAP10 PF07213.6 CEH16943.1 - 0.0015 18.2 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 DAP10 membrane protein EphA2_TM PF14575.1 CEH16943.1 - 0.041 14.2 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 CEH16943.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 UCH PF00443.24 CEH16944.1 - 1.6e-50 171.7 0.0 2.1e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEH16944.1 - 3.2e-21 76.0 0.0 5.1e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CEH16944.1 - 4.5e-09 36.2 7.2 4.5e-09 36.2 5.0 3.2 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein CoA_transf_3 PF02515.12 CEH16944.1 - 0.12 11.6 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 CoA-transferase family III zf-C2H2_4 PF13894.1 CEH16944.1 - 0.63 10.5 4.7 22 5.6 0.9 3.5 2 0 0 2 2 2 0 C2H2-type zinc finger UreD PF01774.12 CEH16945.1 - 8.2e-37 126.7 0.0 2.8e-36 124.9 0.0 1.7 1 1 0 1 1 1 1 UreD urease accessory protein MARVEL PF01284.18 CEH16949.1 - 0.0014 18.4 10.7 0.0026 17.5 7.0 1.7 1 1 0 1 1 1 1 Membrane-associating domain MIG-14_Wnt-bd PF06664.7 CEH16949.1 - 0.003 16.4 3.4 0.0042 15.9 2.3 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Ste5 PF11610.3 CEH16949.1 - 0.21 11.1 4.3 0.085 12.4 0.8 1.9 2 0 0 2 2 2 0 Scaffold protein Ste5-Fus5 binding region Polysacc_synt_C PF14667.1 CEH16949.1 - 2.2 8.0 13.6 0.042 13.6 4.5 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain FtsX PF02687.16 CEH16949.1 - 4.1 7.2 10.8 1.5 8.6 5.4 1.7 1 1 1 2 2 2 0 FtsX-like permease family RRM_1 PF00076.17 CEH16951.1 - 2.3e-23 81.6 0.0 3.2e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH16951.1 - 1.4e-18 66.6 0.0 1.9e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH16951.1 - 8.9e-11 41.4 0.0 1.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IPP-2 PF04979.9 CEH16953.1 - 1.8e-15 57.3 4.6 4.5e-08 33.4 3.1 2.3 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DnaJ PF00226.26 CEH16957.1 - 1.1e-23 82.7 1.9 2.1e-23 81.8 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CEH16957.1 - 4.1e-22 77.8 0.0 1.4e-19 69.7 0.0 2.9 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CEH16957.1 - 1.7e-15 56.8 16.3 3e-15 56.0 11.3 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CEH16957.1 - 0.0015 18.1 6.8 0.11 12.1 0.3 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 CEH16957.1 - 0.82 9.2 8.4 14 5.3 0.1 3.5 2 1 1 3 3 3 0 A2L zinc ribbon domain DZR PF12773.2 CEH16957.1 - 2.3 8.1 10.2 29 4.5 7.4 2.1 1 1 1 2 2 2 0 Double zinc ribbon NodA PF02474.10 CEH16958.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Nodulation protein A (NodA) DPBB_1 PF03330.13 CEH16960.1 - 1.3e-10 41.1 0.1 2.2e-10 40.4 0.1 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEH16960.1 - 0.00055 19.6 0.4 0.0008 19.0 0.2 1.5 1 1 0 1 1 1 1 Barwin family zf-ISL3 PF14690.1 CEH16960.1 - 0.2 11.6 1.2 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Ribosomal_L37 PF08561.5 CEH16961.1 - 2.5e-21 75.0 3.3 8.2e-19 66.9 2.3 2.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 YtpI PF14007.1 CEH16962.1 - 4 7.4 7.6 0.95 9.4 2.5 2.0 2 0 0 2 2 2 0 YtpI-like protein AdoHcyase PF05221.12 CEH16963.1 - 3.7e-136 452.3 0.2 4.2e-136 452.1 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CEH16963.1 - 2.7e-85 284.1 2.6 4.4e-85 283.4 1.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CEH16963.1 - 3.4e-08 32.8 0.1 7.3e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CEH16963.1 - 0.0002 20.7 0.2 0.00032 20.0 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CEH16963.1 - 0.0019 18.1 0.1 0.0056 16.6 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain DUF4448 PF14610.1 CEH16963.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ELFV_dehydrog PF00208.16 CEH16963.1 - 0.031 13.8 0.1 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxysterol_BP PF01237.13 CEH16964.1 - 1.3e-56 191.5 0.0 9.7e-46 155.8 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein Ribosomal_60s PF00428.14 CEH16964.1 - 5.1 7.5 27.2 0.31 11.4 0.9 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein AMPKBI PF04739.10 CEH16965.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain La PF05383.12 CEH16966.1 - 6.9e-18 64.2 0.0 1.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 La domain SHMT PF00464.14 CEH16967.1 - 7.6e-172 571.1 0.0 9e-172 570.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CEH16967.1 - 7.6e-06 25.2 0.0 1.2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Macro PF01661.16 CEH16967.1 - 0.019 14.8 0.3 0.052 13.4 0.0 1.8 2 0 0 2 2 2 0 Macro domain Band_7 PF01145.20 CEH16968.1 - 3.4e-21 75.9 0.5 3.4e-21 75.9 0.3 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 CEH16968.1 - 0.065 12.7 0.1 0.065 12.7 0.1 1.6 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Lactonase PF10282.4 CEH16969.1 - 2.3e-63 214.3 0.0 3e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 CEH16969.1 - 0.0034 15.7 0.0 0.19 9.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 CEH16969.1 - 0.053 13.2 3.0 8.2 6.2 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat zf-C2H2_4 PF13894.1 CEH16970.1 - 0.00028 20.9 13.8 0.0052 17.0 2.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CEH16970.1 - 0.0015 18.7 14.4 0.2 12.0 1.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type CHORD PF04968.7 CEH16970.1 - 5.9 7.2 8.8 8.7 6.6 0.6 2.6 1 1 1 2 2 2 0 CHORD Peptidase_M16 PF00675.15 CEH16972.1 - 1.1e-21 77.1 0.3 2.3e-21 76.0 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CEH16972.1 - 1.1e-14 54.4 0.0 2.2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Ribosomal_L11_N PF03946.9 CEH16973.1 - 7.2e-17 60.6 0.0 1.3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CEH16973.1 - 2.8e-12 46.5 0.5 4.9e-12 45.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_S26e PF01283.14 CEH16974.1 - 2.5e-53 179.1 7.5 2.9e-53 178.9 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e SRP19 PF01922.12 CEH16974.1 - 0.052 14.1 0.5 0.088 13.3 0.3 1.5 1 1 0 1 1 1 0 SRP19 protein DUF3133 PF11331.3 CEH16974.1 - 0.12 11.9 0.3 0.12 11.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) RabGAP-TBC PF00566.13 CEH16976.1 - 3.1e-43 147.7 0.0 8.7e-43 146.2 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FAD_binding_7 PF03441.9 CEH16977.1 - 3e-59 200.5 0.4 4.1e-59 200.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CEH16977.1 - 1e-22 80.6 0.0 2.4e-22 79.4 0.0 1.6 1 1 0 1 1 1 1 DNA photolyase Methyltransf_26 PF13659.1 CEH16978.1 - 6.6e-10 39.0 0.2 1e-09 38.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEH16978.1 - 0.00014 21.2 0.0 0.00067 19.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CEH16978.1 - 0.094 13.0 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.24 CEH16979.1 - 2.2e-35 121.6 0.4 5.6e-35 120.3 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH16979.1 - 5.6e-23 80.6 0.0 2.5e-22 78.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH16979.1 - 6.1e-05 22.9 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CEH16979.1 - 0.017 14.1 0.0 0.047 12.7 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Syntaphilin PF15290.1 CEH16979.1 - 0.08 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp HlyIII PF03006.15 CEH16980.1 - 3.4e-57 193.4 16.4 8.2e-57 192.1 11.4 1.6 1 1 0 1 1 1 1 Haemolysin-III related zf-C3HC4_2 PF13923.1 CEH16983.1 - 5.7e-09 35.8 1.6 1.1e-08 34.9 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH16983.1 - 4.6e-08 32.5 0.3 9.7e-08 31.5 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEH16983.1 - 4.4e-06 26.4 4.7 7.7e-06 25.6 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CEH16983.1 - 2e-05 24.2 0.4 6.2e-05 22.6 0.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CEH16983.1 - 3.8e-05 23.4 1.3 7e-05 22.6 0.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CEH16983.1 - 0.0001 21.9 2.3 0.00019 21.0 1.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEH16983.1 - 0.0091 15.6 5.5 0.015 14.9 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CEH16983.1 - 0.062 13.0 1.7 0.11 12.2 1.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein WD40 PF00400.27 CEH16984.1 - 1.8e-63 208.2 19.1 2e-11 43.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CEH16984.1 - 4e-05 21.9 4.8 0.0087 14.2 1.6 3.6 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CEH16984.1 - 0.025 12.8 0.1 0.81 7.9 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 CEH16984.1 - 0.1 11.3 1.1 3.1 6.4 0.1 3.0 2 1 1 3 3 3 0 Nup133 N terminal like PD40 PF07676.7 CEH16984.1 - 0.13 11.9 2.2 16 5.3 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat La PF05383.12 CEH16985.1 - 6.6e-16 57.8 0.0 1.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 CEH16985.1 - 2e-07 30.5 0.5 3.5e-07 29.7 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH16985.1 - 4.6e-06 26.5 0.1 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH16985.1 - 0.0038 17.0 0.2 0.0082 15.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 CEH16986.1 - 7.1e-37 125.9 0.1 8.5e-37 125.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme adh_short PF00106.20 CEH16987.1 - 3.5e-19 69.3 0.9 1.3e-18 67.5 0.4 1.9 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH16987.1 - 1.5e-12 47.8 0.1 2.4e-12 47.1 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH16987.1 - 0.00011 21.9 0.1 0.00023 20.8 0.0 1.6 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 CEH16987.1 - 0.0012 19.0 0.1 0.0019 18.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 CEH16987.1 - 0.0042 16.1 0.0 0.0094 15.0 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 CEH16987.1 - 0.017 15.4 0.3 0.043 14.2 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 CEH16987.1 - 0.096 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.8 CEH16987.1 - 0.099 11.8 0.3 0.23 10.7 0.2 1.5 1 1 0 1 1 1 0 NmrA-like family Tetraspannin PF00335.15 CEH16988.1 - 1.5e-11 43.9 12.1 2.3e-11 43.4 8.4 1.3 1 0 0 1 1 1 1 Tetraspanin family CcmD PF04995.9 CEH16988.1 - 0.46 10.2 3.4 1.6 8.5 2.4 2.0 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Spindle_Spc25 PF08234.7 CEH16992.1 - 0.05 13.6 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 Kinesin PF00225.18 CEH16993.1 - 0.033 12.8 0.0 0.033 12.8 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain Transglut_core3 PF13471.1 CEH16994.1 - 0.041 13.6 0.4 0.087 12.6 0.3 1.9 1 1 0 1 1 1 0 Transglutaminase-like superfamily DUF3177 PF11375.3 CEH16997.1 - 0.026 14.0 2.3 0.049 13.0 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) Lipase_GDSL PF00657.17 CEH17000.1 - 4.8e-07 29.8 0.0 6.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CEH17000.1 - 2.8e-06 27.6 3.2 5.8e-06 26.5 2.2 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PIG-S PF10510.4 CEH17002.1 - 1.4e-95 320.9 1.4 3.6e-95 319.5 1.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein FAD-oxidase_C PF02913.14 CEH17003.1 - 8.7e-59 198.8 0.1 1.5e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CEH17003.1 - 1.5e-31 108.7 0.2 2.6e-31 107.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain MFS_1_like PF12832.2 CEH17005.1 - 1.8e-19 69.3 0.3 1.8e-19 69.3 0.2 2.5 2 0 0 2 2 2 1 MFS_1 like family RskA PF10099.4 CEH17005.1 - 2.1 8.0 4.7 4.6 6.9 0.2 2.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA tRNA-synt_2b PF00587.20 CEH17008.1 - 2.4e-15 56.5 0.0 4.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FLILHELTA PF10306.4 CEH17008.1 - 3.7e-15 55.7 0.0 1.3e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF4601 PF15373.1 CEH17013.1 - 0.12 11.2 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) AAA PF00004.24 CEH17014.1 - 2.1e-83 277.0 0.0 2.1e-41 141.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEH17014.1 - 1.2e-10 41.7 4.5 0.00022 21.2 0.2 4.9 3 2 2 5 5 4 2 AAA ATPase domain AAA_5 PF07728.9 CEH17014.1 - 1.8e-10 40.6 0.0 4.4e-05 23.2 0.0 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CEH17014.1 - 2e-09 37.0 0.0 2.7e-05 23.6 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein RuvB_N PF05496.7 CEH17014.1 - 7.2e-09 35.0 0.0 0.00033 19.7 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CEH17014.1 - 1.3e-08 34.9 0.0 0.0014 18.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CEH17014.1 - 1.7e-08 34.7 0.4 0.0019 18.3 0.1 4.2 2 2 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CEH17014.1 - 6.7e-08 32.1 2.9 0.0058 16.0 0.1 4.0 2 2 0 3 3 3 2 AAA domain TIP49 PF06068.8 CEH17014.1 - 6.8e-08 31.6 0.0 0.005 15.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 CEH17014.1 - 7.1e-08 33.2 0.0 0.00086 20.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CEH17014.1 - 2.4e-06 27.4 0.0 0.0013 18.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CEH17014.1 - 4.8e-06 26.4 0.0 0.0061 16.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CEH17014.1 - 6.1e-06 25.4 0.0 0.0042 16.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 CEH17014.1 - 4e-05 23.2 0.1 0.013 15.2 0.0 3.4 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 CEH17014.1 - 0.00015 21.0 1.3 0.28 10.3 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CEH17014.1 - 0.00029 20.9 0.0 0.48 10.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 CEH17014.1 - 0.00062 20.0 0.0 0.043 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CEH17014.1 - 0.00069 19.2 0.9 0.0097 15.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CEH17014.1 - 0.00078 19.4 0.1 1.3 8.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 CEH17014.1 - 0.00094 18.7 0.0 0.38 10.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CEH17014.1 - 0.0075 15.9 0.0 1.8 8.2 0.0 3.3 2 2 1 3 3 3 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 CEH17014.1 - 0.011 15.7 0.0 4.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 CEH17014.1 - 0.014 14.9 0.0 2.5 7.5 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 CEH17014.1 - 0.026 13.4 0.0 0.48 9.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NACHT PF05729.7 CEH17014.1 - 0.028 14.0 0.0 4.3 6.9 0.0 3.9 4 0 0 4 4 4 0 NACHT domain AAA_11 PF13086.1 CEH17014.1 - 0.03 13.8 0.0 0.57 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CEH17014.1 - 0.031 13.4 0.1 0.75 8.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.12 CEH17014.1 - 0.034 13.0 0.0 0.77 8.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 IPT PF01745.11 CEH17014.1 - 0.058 12.5 0.1 1.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase ABC_tran PF00005.22 CEH17014.1 - 0.06 13.6 0.0 1.9 8.7 0.0 2.8 2 1 0 2 2 2 0 ABC transporter KaiC PF06745.8 CEH17014.1 - 0.072 12.1 0.0 4.5 6.3 0.0 2.9 3 0 0 3 3 3 0 KaiC Rad17 PF03215.10 CEH17014.1 - 0.15 10.7 0.1 0.53 8.9 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein SKI PF01202.17 CEH17014.1 - 0.22 11.3 3.2 17 5.2 0.2 3.1 3 0 0 3 3 3 0 Shikimate kinase RRM_1 PF00076.17 CEH17015.1 - 7.6e-17 60.7 0.0 3.9e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH17015.1 - 1.2e-13 50.6 0.0 9.7e-11 41.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH17015.1 - 2.8e-11 43.2 0.0 0.0003 20.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CEH17015.1 - 0.068 12.9 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 DEAD PF00270.24 CEH17016.1 - 4.8e-12 45.6 0.0 9.6e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH17016.1 - 6.3e-06 25.9 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Macoilin PF09726.4 CEH17016.1 - 1.5 7.0 2.8 2.3 6.4 1.9 1.3 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_B PF00136.16 CEH17017.1 - 1.7e-79 267.7 0.0 2.5e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CEH17017.1 - 3.2e-23 82.1 0.0 9.3e-11 41.1 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.8 CEH17017.1 - 0.077 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral zf-C4pol PF14260.1 CEH17018.1 - 3.3e-08 33.4 10.9 2.4e-05 24.2 5.8 2.2 2 0 0 2 2 2 2 C4-type zinc-finger of DNA polymerase delta zf-rbx1 PF12678.2 CEH17018.1 - 0.067 13.2 6.8 2.1 8.5 0.5 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger DUF3446 PF11928.3 CEH17018.1 - 0.56 10.4 8.2 1.1 9.5 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) RecR PF02132.10 CEH17018.1 - 0.71 9.3 8.5 0.74 9.2 2.1 2.3 2 0 0 2 2 2 0 RecR protein FYVE PF01363.16 CEH17018.1 - 2.7 7.9 9.6 6.1 6.8 6.7 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-UBR PF02207.15 CEH17018.1 - 7 6.4 9.7 2.7 7.8 2.7 2.2 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) zf-HC5HC2H PF13771.1 CEH17018.1 - 9.1 6.5 9.7 0.73 10.0 1.0 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain GNAT_acetyltr_2 PF13718.1 CEH17021.1 - 1.4e-73 246.3 0.0 4.5e-73 244.7 0.0 1.8 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CEH17021.1 - 5.1e-62 208.6 0.0 1.1e-61 207.5 0.0 1.6 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 CEH17021.1 - 2e-33 113.9 0.0 7.2e-33 112.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CEH17021.1 - 7.9e-19 67.6 0.2 3e-18 65.7 0.1 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 CEH17021.1 - 8e-05 22.7 0.0 0.0027 17.8 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEH17021.1 - 0.0057 16.6 0.1 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CEH17021.1 - 0.067 12.9 0.2 16 5.3 0.0 2.7 2 0 0 2 2 2 0 FR47-like protein DnaJ PF00226.26 CEH17022.1 - 3e-25 87.7 0.2 4.7e-25 87.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CEH17022.1 - 7e-20 70.7 0.1 1.3e-17 63.4 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CEH17022.1 - 1.8e-11 43.8 19.3 3e-11 43.2 13.4 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CEH17022.1 - 0.13 12.0 7.3 0.39 10.4 1.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 CEH17022.1 - 0.88 9.4 9.8 4.2 7.2 1.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon SKN1 PF03935.10 CEH17024.1 - 1.2e-185 617.4 1.4 1.4e-185 617.2 1.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Asp PF00026.18 CEH17025.1 - 3.2e-113 378.1 0.0 3.7e-113 377.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEH17025.1 - 1.3e-11 44.7 0.0 2.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEH17025.1 - 1.1e-06 28.3 0.0 0.00012 21.6 0.0 2.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CEH17025.1 - 2e-05 24.9 0.0 0.0087 16.5 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease Pkinase PF00069.20 CEH17026.1 - 2.8e-74 249.5 0.0 3.6e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17026.1 - 5.2e-36 124.0 0.0 7.9e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH17026.1 - 1.1e-08 34.4 0.0 1.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CEH17026.1 - 0.00098 18.5 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.6 CEH17026.1 - 0.028 14.5 0.7 0.069 13.3 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) YukC PF10140.4 CEH17026.1 - 0.068 11.7 0.1 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF3116 PF11313.3 CEH17027.1 - 0.024 14.2 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) Ku PF02735.11 CEH17029.1 - 4.4e-28 98.0 0.0 6.6e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CEH17029.1 - 9e-11 41.6 0.0 1e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 CEH17029.1 - 7.3e-10 38.1 0.0 1.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 CEH17029.1 - 1.5e-05 25.4 0.0 3.8e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm TPR_14 PF13428.1 CEH17030.1 - 2.4e-07 30.7 34.9 0.0025 18.2 0.4 9.3 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 CEH17030.1 - 3.7e-07 29.6 20.2 7e-05 22.3 0.4 6.3 6 2 0 7 7 7 3 TPR repeat TPR_1 PF00515.23 CEH17030.1 - 5.9e-07 28.8 4.0 0.055 13.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CEH17030.1 - 6.6e-05 22.8 1.8 4.7 7.6 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEH17030.1 - 0.0002 21.9 2.8 0.0002 21.9 1.9 7.6 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEH17030.1 - 0.00047 20.0 1.9 0.00047 20.0 1.3 7.7 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEH17030.1 - 0.0071 16.0 0.2 2.8 7.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEH17030.1 - 0.0086 16.3 2.0 0.017 15.4 1.2 6.5 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 CEH17030.1 - 0.024 14.5 20.1 0.049 13.5 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.5 CEH17030.1 - 0.036 12.8 1.0 0.079 11.7 0.1 1.9 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.1 CEH17030.1 - 0.12 12.2 12.6 2.5 8.1 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Pkinase PF00069.20 CEH17031.1 - 9.8e-69 231.3 0.0 1.3e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17031.1 - 1e-48 165.7 0.0 1.6e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CEH17031.1 - 7e-22 77.3 0.0 1.7e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 CEH17031.1 - 6.7e-12 45.0 0.0 1.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CEH17031.1 - 6e-10 39.1 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 CEH17031.1 - 8.4e-05 21.6 0.0 0.00024 20.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RA PF00788.18 CEH17031.1 - 0.036 14.5 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain PPP4R2 PF09184.6 CEH17031.1 - 2 7.9 11.3 3.7 7.0 7.9 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.7 CEH17031.1 - 9.8 3.9 9.5 14 3.4 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family DnaJ PF00226.26 CEH17033.1 - 5e-19 67.7 1.1 7.8e-19 67.1 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain PRY PF13765.1 CEH17033.1 - 0.073 12.6 0.3 3.2 7.3 0.1 2.4 2 0 0 2 2 2 0 SPRY-associated domain Bacteriocin_IIc PF10439.4 CEH17033.1 - 0.26 11.4 11.2 0.15 12.2 3.3 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.1 CEH17033.1 - 0.73 9.5 7.1 0.62 9.7 0.2 2.3 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Methyltransf_28 PF02636.12 CEH17034.1 - 7.3e-62 209.0 0.0 8.9e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Mito_carr PF00153.22 CEH17035.1 - 2e-73 242.1 0.7 1.1e-25 89.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EVE PF01878.13 CEH17037.1 - 1.2e-22 80.5 0.0 2.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 EVE domain PDH PF02153.12 CEH17038.1 - 4.5e-13 48.6 0.0 7.6e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 CEH17038.1 - 6.3e-08 32.9 0.0 1.9e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CEH17038.1 - 2.3e-06 27.5 0.0 4.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 CEH17038.1 - 0.00023 20.3 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 CEH17038.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 CEH17038.1 - 0.0035 17.4 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CEH17038.1 - 0.0098 15.5 0.0 0.022 14.4 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 CEH17038.1 - 0.014 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.13 CEH17038.1 - 0.056 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 CEH17038.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PAP1 PF08601.5 CEH17039.1 - 4.7 6.8 8.0 0.091 12.4 0.5 1.8 2 0 0 2 2 2 0 Transcription factor PAP1 RAP1 PF07218.6 CEH17039.1 - 6.4 4.7 9.5 1.7 6.6 2.5 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) HEAT PF02985.17 CEH17040.1 - 2.5e-39 129.8 23.7 0.0032 17.4 0.0 13.6 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.1 CEH17040.1 - 5.6e-32 109.8 9.9 1.4e-08 34.8 0.0 7.0 3 3 2 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 CEH17040.1 - 1.1e-11 44.7 25.9 0.54 10.8 0.0 9.3 8 2 2 10 10 10 6 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CEH17040.1 - 1.3e-11 44.7 0.6 0.025 14.9 0.0 6.3 3 2 4 7 7 7 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CEH17040.1 - 2.6e-05 23.7 0.6 0.2 10.9 0.0 4.6 2 2 2 4 4 4 2 CLASP N terminal Arm PF00514.18 CEH17040.1 - 0.00045 19.9 2.2 8 6.4 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 CEH17040.1 - 0.00053 18.4 7.1 0.11 10.8 0.1 4.4 3 1 0 4 4 4 2 Adaptin N terminal region HEAT_PBS PF03130.11 CEH17040.1 - 0.084 13.3 0.2 9.6 7.0 0.0 4.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF2435 PF10363.4 CEH17040.1 - 0.19 11.6 2.0 7.1 6.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) DUF2470 PF10615.4 CEH17041.1 - 1.3e-07 31.7 0.0 2.9e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 CEH17041.1 - 0.0076 16.1 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Syja_N PF02383.13 CEH17042.1 - 1.4e-86 290.1 0.0 2.1e-86 289.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Phage_tail_T PF06223.7 CEH17042.1 - 0.0046 17.3 0.3 0.027 14.8 0.0 2.4 3 0 0 3 3 3 1 Minor tail protein T MAD PF05557.8 CEH17043.1 - 1.4e-31 109.3 14.7 1.4e-31 109.3 10.2 2.1 2 0 0 2 2 2 1 Mitotic checkpoint protein TLE_N PF03920.10 CEH17043.1 - 2.1 8.1 18.1 0.15 11.9 0.2 4.4 4 1 0 5 5 5 0 Groucho/TLE N-terminal Q-rich domain DUF1175 PF06672.6 CEH17044.1 - 0.092 12.0 0.7 0.17 11.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1175) CotE PF10628.4 CEH17045.1 - 0.058 12.7 0.5 0.099 12.0 0.3 1.4 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) FTR1 PF03239.9 CEH17046.1 - 1.6e-49 168.5 5.3 4e-31 108.0 2.0 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family Herpes_glycop PF01528.11 CEH17046.1 - 0.00042 19.1 0.0 0.0021 16.8 0.0 2.0 2 0 0 2 2 2 1 Herpesvirus glycoprotein M DUF3169 PF11368.3 CEH17046.1 - 0.042 13.0 0.2 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF3112 PF11309.3 CEH17046.1 - 0.048 13.4 0.0 0.18 11.5 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) OPT PF03169.10 CEH17047.1 - 2.7e-113 379.5 10.7 6e-113 378.4 7.4 1.5 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Pex14_N PF04695.8 CEH17047.1 - 0.072 13.1 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4349 PF14257.1 CEH17047.1 - 0.12 11.5 0.0 0.43 9.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Cu-oxidase_2 PF07731.9 CEH17048.1 - 6.5e-35 119.6 4.9 3.8e-34 117.1 2.3 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 CEH17048.1 - 1.8e-21 76.7 0.2 2.1e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Mre11_DNA_bind PF04152.9 CEH17049.1 - 1.6e-46 158.3 0.5 2.7e-46 157.6 0.3 1.4 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CEH17049.1 - 3.6e-21 75.4 0.4 6.6e-21 74.6 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEH17049.1 - 4.6e-07 29.8 0.0 1.6e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PBP1_TM PF14812.1 CEH17049.1 - 0.57 10.5 23.8 0.076 13.3 3.3 4.3 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Arm PF00514.18 CEH17050.1 - 1.2e-91 297.7 11.5 1.6e-12 46.7 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CEH17050.1 - 2e-24 85.6 2.4 8.5e-08 32.3 0.0 5.6 1 1 4 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 CEH17050.1 - 5.3e-21 74.4 1.0 1.2e-05 25.6 0.0 6.1 4 1 2 6 6 6 5 HEAT-like repeat HEAT PF02985.17 CEH17050.1 - 7.8e-14 50.4 5.0 0.00026 20.8 0.0 7.1 8 0 0 8 8 8 3 HEAT repeat Arm_2 PF04826.8 CEH17050.1 - 2.9e-07 29.8 0.0 0.062 12.3 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 CEH17050.1 - 1.5e-06 26.8 0.0 4.9e-05 21.8 0.0 2.7 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 CEH17050.1 - 0.00011 22.0 0.1 0.064 13.1 0.0 4.2 3 2 1 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 CEH17050.1 - 0.0019 18.4 0.9 0.33 11.5 0.1 4.5 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 CEH17050.1 - 0.0027 17.5 6.2 0.51 10.3 0.0 4.5 3 2 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 CEH17050.1 - 0.11 10.7 0.1 2.7 6.1 0.0 2.6 2 1 2 4 4 4 0 Proteasome non-ATPase 26S subunit GTP_cyclohydro2 PF00925.15 CEH17051.1 - 5.7e-70 233.9 1.5 8.1e-61 204.1 0.3 2.5 2 0 0 2 2 2 2 GTP cyclohydrolase II CCDC155 PF14662.1 CEH17052.1 - 0.031 13.8 6.7 0.044 13.3 4.6 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 LCD1 PF09798.4 CEH17052.1 - 6.2 4.6 6.4 8.2 4.2 4.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Pkinase PF00069.20 CEH17056.1 - 1.5e-59 201.2 0.0 2e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17056.1 - 5e-46 156.8 0.0 6.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH17056.1 - 1.8e-05 23.8 0.0 0.0051 15.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 CEH17056.1 - 6.1e-05 22.4 0.1 0.00015 21.2 0.1 1.6 1 1 1 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.6 CEH17056.1 - 0.0038 16.1 0.2 0.0068 15.2 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RabGAP-TBC PF00566.13 CEH17058.1 - 2.3e-31 108.9 2.6 9.1e-29 100.4 0.1 3.1 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Cep57_MT_bd PF06657.8 CEH17059.1 - 1.2e-08 34.7 2.4 1.2e-08 34.7 0.5 1.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 rve_3 PF13683.1 CEH17061.1 - 0.038 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DUF1708 PF08101.6 CEH17062.1 - 2.5e-15 56.2 0.0 2.5e-13 49.6 0.0 2.8 3 1 0 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 CEH17062.1 - 0.00069 19.2 0.0 0.0031 17.1 0.0 2.1 3 0 0 3 3 3 1 RhoGAP domain DENN PF02141.16 CEH17063.1 - 7.5e-21 74.6 0.0 1.2e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Syntaxin PF00804.20 CEH17063.1 - 0.21 11.7 13.4 1.2 9.3 1.1 2.9 2 0 0 2 2 2 0 Syntaxin DXP_redisom_C PF08436.7 CEH17063.1 - 0.21 11.5 0.0 0.9 9.4 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal OmpH PF03938.9 CEH17063.1 - 0.45 10.4 10.9 0.13 12.1 4.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 CEH17063.1 - 0.47 9.4 7.7 0.94 8.4 5.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 CEH17063.1 - 1.8 7.6 10.7 0.36 10.0 4.5 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.6 CEH17063.1 - 3 6.4 5.6 4.7 5.7 3.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) YTH PF04146.10 CEH17064.1 - 8.3e-45 151.8 0.0 1.7e-44 150.8 0.0 1.5 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 CEH17064.1 - 0.011 15.3 0.6 2.4 7.8 0.1 2.9 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH17064.1 - 0.032 14.0 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2052 PF09747.4 CEH17064.1 - 0.14 12.0 0.7 0.34 10.8 0.5 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Lysine_decarbox PF03641.9 CEH17065.1 - 3.5e-32 111.0 0.0 1.1e-31 109.4 0.0 1.8 1 1 0 1 1 1 1 Possible lysine decarboxylase ABC_tran PF00005.22 CEH17065.1 - 2.8e-14 53.5 0.3 1.7e-07 31.5 0.0 2.8 2 1 1 3 3 3 2 ABC transporter AAA_21 PF13304.1 CEH17065.1 - 2.5e-09 37.5 0.7 0.0026 17.7 0.4 2.2 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CEH17065.1 - 1.4e-06 27.6 0.0 0.006 15.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CEH17065.1 - 0.00052 19.4 0.1 0.0013 18.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 CEH17065.1 - 0.0011 18.9 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CEH17065.1 - 0.0012 18.3 0.1 0.69 9.2 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain AAA_17 PF13207.1 CEH17065.1 - 0.0031 18.3 0.0 0.0074 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEH17065.1 - 0.0038 17.2 0.7 0.01 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CEH17065.1 - 0.007 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CEH17065.1 - 0.037 13.5 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 CEH17065.1 - 0.042 13.9 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CEH17065.1 - 0.043 13.0 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 CEH17065.1 - 0.043 14.1 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CEH17065.1 - 0.094 12.5 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CEH17065.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 CEH17065.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CEH17065.1 - 0.13 12.8 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein ADH_zinc_N PF00107.21 CEH17066.1 - 1.1e-11 44.3 1.2 2.4e-11 43.2 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH17066.1 - 8.9e-10 39.5 0.1 5.4e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH17066.1 - 3.7e-06 26.6 0.0 6.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 CEH17067.1 - 1.8e-19 70.4 0.0 2.6e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CEH17067.1 - 0.0022 16.9 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 CEH17067.1 - 0.0087 15.3 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DeoC PF01791.4 CEH17068.1 - 7.9e-34 116.9 2.2 9.4e-34 116.7 1.5 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.16 CEH17068.1 - 0.0014 17.9 0.3 0.0045 16.2 0.0 1.9 2 1 1 3 3 3 1 Histidine biosynthesis protein Ribosomal_L13e PF01294.13 CEH17069.1 - 3.7e-51 173.1 5.0 3.7e-51 173.1 3.5 1.3 2 0 0 2 2 2 1 Ribosomal protein L13e Ribosomal_S10 PF00338.17 CEH17070.1 - 3.6e-16 58.8 0.0 7e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FA_hydroxylase PF04116.8 CEH17072.1 - 9.5e-15 54.9 14.9 9.5e-15 54.9 10.4 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily 7tm_1 PF00001.16 CEH17073.1 - 3.8 6.5 10.8 0.99 8.4 4.3 2.3 2 1 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) YqzM PF14141.1 CEH17073.1 - 7.8 6.3 6.0 0.79 9.5 0.8 1.8 2 0 0 2 2 2 0 YqzM-like protein ABC_membrane PF00664.18 CEH17074.1 - 2.1e-43 148.7 4.7 3.2e-19 69.3 0.1 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 CEH17074.1 - 3.1e-33 114.9 0.0 2.1e-25 89.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CEH17074.1 - 3.6e-10 39.4 0.0 0.0037 16.5 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CEH17074.1 - 2.4e-05 24.4 0.0 2.4 8.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CEH17074.1 - 0.0012 18.3 0.8 0.0075 15.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CEH17074.1 - 0.0024 18.0 0.0 1.3 9.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 CEH17074.1 - 0.0041 16.9 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_29 PF13555.1 CEH17074.1 - 0.015 14.8 0.0 0.038 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 CEH17074.1 - 0.016 16.0 0.0 0.035 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CEH17074.1 - 0.051 13.0 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 CEH17074.1 - 0.086 13.1 0.0 0.29 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CEH17074.1 - 0.18 11.7 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.17 CEH17074.1 - 0.24 10.2 0.1 0.75 8.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain NUDIX_2 PF13869.1 CEH17075.1 - 1.2e-79 266.0 0.0 1.3e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Ammonium_transp PF00909.16 CEH17076.1 - 9.3e-109 363.5 27.9 1.1e-108 363.3 19.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pil1 PF13805.1 CEH17078.1 - 3e-11 42.9 0.1 6.8e-11 41.8 0.1 1.6 1 0 0 1 1 1 1 Eisosome component PIL1 RhoGEF PF00621.15 CEH17078.1 - 0.54 10.1 0.0 0.78 9.5 0.0 1.2 1 0 0 1 1 1 0 RhoGEF domain Tub_2 PF04525.7 CEH17079.1 - 3.2e-21 75.5 0.0 3.9e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 Sec3_C PF09763.4 CEH17080.1 - 0.028 12.5 3.9 0.035 12.2 2.7 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF4366 PF14283.1 CEH17080.1 - 0.031 13.6 0.0 0.059 12.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) RR_TM4-6 PF06459.7 CEH17080.1 - 0.035 14.0 2.2 0.055 13.3 1.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4448 PF14610.1 CEH17080.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) PRCC PF10253.4 CEH17080.1 - 0.2 12.3 13.0 0.41 11.3 9.0 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2217 PF10265.4 CEH17080.1 - 0.57 8.8 11.7 0.72 8.5 8.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF566 PF04484.7 CEH17080.1 - 2.5 7.5 22.8 3.5 7.0 15.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Plasmodium_Vir PF05795.6 CEH17080.1 - 6.1 5.9 10.3 14 4.7 7.1 1.6 1 1 0 1 1 1 0 Plasmodium vivax Vir protein UQ_con PF00179.21 CEH17081.1 - 2.3e-18 65.9 0.0 4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Fungal_trans PF04082.13 CEH17082.1 - 1.3e-17 63.5 0.0 2.9e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH17082.1 - 2.8e-07 30.3 11.1 5.2e-07 29.4 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COPIIcoated_ERV PF07970.7 CEH17083.1 - 1.8e-63 214.1 0.0 3.5e-63 213.1 0.0 1.5 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CEH17083.1 - 8e-32 109.0 0.7 1.5e-31 108.2 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TPPK_C PF12555.3 CEH17083.1 - 0.033 13.9 1.0 0.086 12.5 0.7 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal TPR_11 PF13414.1 CEH17084.1 - 3.3e-19 68.2 5.2 1.1e-13 50.5 1.4 2.9 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CEH17084.1 - 4.3e-11 41.9 1.8 0.00022 20.6 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEH17084.1 - 1.8e-10 39.9 3.4 0.0052 16.5 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 CEH17084.1 - 1.2e-08 34.6 0.8 3.5e-08 33.1 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 CEH17084.1 - 2.2e-05 24.2 0.5 0.095 12.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEH17084.1 - 5.5e-05 23.7 6.3 0.0018 18.8 0.3 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEH17084.1 - 0.00026 21.2 4.8 0.0074 16.5 0.2 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH17084.1 - 0.25 12.1 11.2 1.4 9.7 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Aa_trans PF01490.13 CEH17088.1 - 5.2e-46 156.9 29.2 1.9e-38 132.0 14.0 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DUF4231 PF14015.1 CEH17088.1 - 3.5 7.6 8.9 15 5.6 0.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) gag_pre-integrs PF13976.1 CEH17091.1 - 0.018 14.6 0.5 0.044 13.4 0.3 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain Cation_efflux PF01545.16 CEH17093.1 - 4.2e-23 81.8 1.2 6.7e-23 81.1 0.9 1.3 1 0 0 1 1 1 1 Cation efflux family ICL PF00463.16 CEH17094.1 - 2.6e-190 633.1 0.0 2.9e-190 632.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CEH17094.1 - 5.1e-11 42.2 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Chitin_synth_2 PF03142.10 CEH17095.1 - 1.3e-239 796.0 0.3 1.9e-239 795.5 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CEH17095.1 - 1.4e-147 492.6 0.0 2.1e-147 492.1 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 CEH17095.1 - 2.8e-19 68.6 4.5 5.7e-12 45.2 0.2 4.3 5 0 0 5 5 5 2 DEK C terminal domain Cyt-b5 PF00173.23 CEH17095.1 - 1.4e-17 63.2 0.1 6.9e-12 45.0 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 CEH17095.1 - 6.4e-17 61.8 4.1 2.4e-16 60.0 2.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEH17095.1 - 7.1e-17 61.9 0.0 4.3e-13 49.5 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CEH17095.1 - 0.00024 20.8 0.0 0.034 13.8 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEH17095.1 - 0.002 17.4 0.0 0.02 14.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Aldedh PF00171.17 CEH17096.1 - 1.9e-148 494.6 0.0 2.2e-148 494.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CEH17096.1 - 0.0011 17.7 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) HAD PF12710.2 CEH17097.1 - 8.7e-06 26.0 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 CEH17098.1 - 0.0056 15.8 0.0 0.0076 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 CEH17099.1 - 1.2e-14 54.0 0.0 1.5e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17099.1 - 2.3e-06 26.8 0.0 4.5e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH17099.1 - 0.0033 16.4 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Rad60-SLD PF11976.3 CEH17100.1 - 6.7e-17 60.9 0.1 9.1e-17 60.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CEH17100.1 - 1.3e-06 27.7 0.0 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family TPR_11 PF13414.1 CEH17101.1 - 8.7e-47 156.6 14.3 4e-15 55.2 0.2 7.5 4 3 2 7 7 7 6 TPR repeat TPR_1 PF00515.23 CEH17101.1 - 1.4e-31 106.7 7.9 9.9e-08 31.2 0.0 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 CEH17101.1 - 8.9e-30 100.1 13.2 2.3e-06 27.0 0.0 10.9 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 CEH17101.1 - 9.8e-24 83.4 27.3 7.2e-07 29.7 0.2 7.7 6 2 3 9 9 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 CEH17101.1 - 1.8e-17 61.9 2.2 0.088 13.0 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 CEH17101.1 - 3.4e-16 58.9 17.9 0.0011 18.8 0.2 7.1 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 CEH17101.1 - 2.3e-13 49.4 20.5 0.046 14.3 0.3 10.0 7 3 3 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEH17101.1 - 1.1e-11 43.5 7.6 1.2 9.1 0.1 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 CEH17101.1 - 2.8e-11 43.5 21.2 0.00024 21.3 0.2 7.2 5 2 1 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 CEH17101.1 - 5.6e-10 39.2 9.4 0.038 14.1 0.0 5.0 3 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CEH17101.1 - 6.7e-09 34.9 9.6 0.0022 17.6 0.0 7.8 8 2 2 10 10 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEH17101.1 - 6.8e-08 32.2 7.9 0.0018 18.0 0.1 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 CEH17101.1 - 0.00017 20.7 10.7 0.079 11.9 0.3 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat Rapsyn_N PF10579.4 CEH17101.1 - 0.019 14.7 0.2 9 6.1 0.0 3.1 3 1 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.1 CEH17101.1 - 0.16 12.5 20.1 20 5.9 0.0 8.8 9 1 1 10 10 8 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CEH17101.1 - 0.21 10.8 3.1 5.1 6.4 0.0 3.4 3 0 0 3 3 3 0 SHNi-TPR DUF3712 PF12505.3 CEH17102.1 - 2.5e-97 321.5 26.1 1.5e-22 79.9 0.0 8.1 7 0 0 7 7 7 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 CEH17102.1 - 1.3e-09 38.2 7.5 0.11 12.8 0.1 7.2 7 0 0 7 7 7 3 Late embryogenesis abundant protein LRR_6 PF13516.1 CEH17104.1 - 1.4e-09 36.9 6.5 1.3 9.3 0.1 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.2 CEH17104.1 - 1.2e-06 27.9 3.8 0.0008 18.9 0.2 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEH17104.1 - 6.3e-05 22.4 1.7 13 6.2 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat GAT PF03127.9 CEH17104.1 - 0.00012 21.9 0.4 0.00033 20.5 0.3 1.8 1 0 0 1 1 1 1 GAT domain LRR_8 PF13855.1 CEH17104.1 - 0.066 12.9 7.6 0.049 13.3 1.0 3.2 2 2 0 2 2 2 0 Leucine rich repeat PP1_inhibitor PF05361.7 CEH17104.1 - 0.21 11.2 3.0 6 6.5 0.1 3.2 2 1 1 3 3 3 0 PKC-activated protein phosphatase-1 inhibitor FUSC PF04632.7 CEH17104.1 - 0.59 8.4 12.2 0.83 7.9 8.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LRR_7 PF13504.1 CEH17104.1 - 7.8 7.1 10.1 74 4.2 0.1 4.8 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 CEH17105.1 - 3e-05 23.6 0.7 0.063 13.3 0.2 2.9 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.2 CEH17105.1 - 0.00066 19.2 0.4 1.4 8.6 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CEH17105.1 - 0.006 16.4 0.3 5.7 7.3 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 CEH17105.1 - 0.011 15.8 0.4 13 6.5 0.0 3.2 2 0 0 2 2 2 0 Leucine rich repeat Sugar_tr PF00083.19 CEH17106.1 - 5.5e-14 51.5 19.4 1.1e-13 50.6 3.7 2.5 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 CEH17106.1 - 1.1e-08 34.2 6.6 1.1e-08 34.2 4.6 3.1 1 1 1 3 3 3 1 Major Facilitator Superfamily Peptidase_M16 PF00675.15 CEH17107.1 - 2.3e-09 37.1 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF2052 PF09747.4 CEH17108.1 - 0.011 15.6 1.0 0.017 15.0 0.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2457 PF10446.4 CEH17108.1 - 1.1 7.8 11.9 1.5 7.4 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PCI PF01399.22 CEH17109.1 - 0.00027 21.2 0.0 0.0044 17.3 0.0 2.5 2 1 0 2 2 2 1 PCI domain TPR_19 PF14559.1 CEH17109.1 - 0.017 15.4 0.1 0.15 12.3 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.2 CEH17112.1 - 0.013 15.1 0.1 0.038 13.7 0.0 1.8 2 0 0 2 2 2 0 F-box-like FAD_binding_3 PF01494.14 CEH17113.1 - 1.7e-30 106.2 0.0 2.3e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEH17113.1 - 1.4e-08 34.0 0.2 4.2e-05 22.6 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEH17113.1 - 6.4e-06 26.1 0.1 1.3e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CEH17113.1 - 7.2e-06 26.3 0.4 9.5e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CEH17113.1 - 0.00056 18.6 0.0 1 7.9 0.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.19 CEH17113.1 - 0.0012 17.7 0.0 0.0028 16.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 CEH17113.1 - 0.0016 18.1 0.1 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CEH17113.1 - 0.0026 17.2 0.1 0.0042 16.5 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 CEH17113.1 - 0.0058 15.7 0.1 0.009 15.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 CEH17113.1 - 0.032 12.7 0.1 0.69 8.3 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 CEH17113.1 - 0.039 12.8 0.1 0.071 11.9 0.0 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 CEH17113.1 - 0.068 12.0 0.2 0.77 8.6 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CEH17113.1 - 0.073 12.9 0.2 0.23 11.3 0.2 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 CEH17115.1 - 3.9e-59 199.9 0.0 5.5e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17115.1 - 1.6e-30 106.0 0.0 2.2e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 CEH17115.1 - 1.1e-16 59.9 0.1 2.3e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 CEH17115.1 - 2.1e-05 23.7 0.0 3.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CEH17115.1 - 0.00036 19.5 0.0 0.00055 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEH17115.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CEH17115.1 - 0.32 10.2 0.0 0.55 9.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL bZIP_1 PF00170.16 CEH17117.1 - 0.00041 20.2 13.8 0.00041 20.2 9.6 2.6 3 1 0 3 3 3 1 bZIP transcription factor Herpes_U30 PF04523.8 CEH17117.1 - 0.11 9.9 2.3 0.1 10.0 0.3 1.7 2 0 0 2 2 2 0 Herpes virus tegument protein U30 Glutaredoxin2_C PF04399.8 CEH17117.1 - 0.16 11.5 0.2 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Meth_synt_2 PF01717.13 CEH17118.1 - 4.5e-142 472.8 0.0 4.2e-134 446.6 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CEH17118.1 - 1.1e-117 392.7 0.0 1.7e-104 349.4 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 CEH17118.1 - 0.00034 19.9 0.6 0.00093 18.5 0.4 1.8 1 0 0 1 1 1 1 Short C-terminal domain RRM_6 PF14259.1 CEH17119.1 - 1.7e-13 50.3 0.0 4.8e-06 26.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEH17119.1 - 6.6e-13 48.0 0.0 0.0035 16.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MPP6 PF10175.4 CEH17119.1 - 0.037 14.4 0.2 0.18 12.2 0.0 2.3 2 0 0 2 2 2 0 M-phase phosphoprotein 6 RRM_5 PF13893.1 CEH17119.1 - 0.14 11.9 0.0 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mog1 PF04603.7 CEH17120.1 - 1.2e-25 90.1 0.0 1.8e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein LacAB_rpiB PF02502.13 CEH17122.1 - 7.4e-31 106.6 0.0 8.7e-31 106.4 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4514 PF14986.1 CEH17122.1 - 0.0041 16.8 0.6 0.012 15.4 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4514) ECH PF00378.15 CEH17123.1 - 5.4e-23 81.3 0.0 1.1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CEH17123.1 - 1.5e-21 76.7 0.0 4.5e-21 75.1 0.0 1.8 1 1 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region MFS_1 PF07690.11 CEH17124.1 - 7.1e-26 90.7 17.6 1.4e-25 89.7 12.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UCR_Fe-S_N PF10399.4 CEH17124.1 - 4.6 6.4 7.1 2.1 7.6 1.2 2.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF4203 PF13886.1 CEH17126.1 - 4.2e-06 26.3 0.0 6.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF59 PF01883.14 CEH17127.1 - 3.6e-10 39.6 0.0 8.4e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 MoCF_biosynth PF00994.19 CEH17128.1 - 3.7e-56 188.5 0.2 6.4e-29 100.2 0.0 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 CEH17128.1 - 3.5e-30 104.5 0.1 6.2e-30 103.6 0.1 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 CEH17128.1 - 2.6e-11 43.3 0.1 1.3e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) T2SE PF00437.15 CEH17128.1 - 0.00023 20.1 0.5 0.67 8.8 0.0 3.1 4 0 0 4 4 4 2 Type II/IV secretion system protein CarboxypepD_reg PF13620.1 CEH17128.1 - 0.038 14.0 0.3 0.42 10.6 0.0 2.6 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain DNA_ligase_aden PF01653.13 CEH17128.1 - 0.25 10.2 0.0 0.39 9.6 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain SNF2_N PF00176.18 CEH17129.1 - 2.3e-27 95.5 0.1 3.2e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 CEH17129.1 - 2.9e-13 49.6 0.0 9.2e-13 48.0 0.0 1.8 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase TP6A_N PF04406.9 CEH17130.1 - 1e-09 37.8 0.0 1.8e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 CEH17130.1 - 0.013 15.3 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) ubiquitin PF00240.18 CEH17130.1 - 0.16 11.3 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family Glyco_hydro_16 PF00722.16 CEH17131.1 - 1.1e-28 99.8 0.1 2.1e-28 98.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Methyltransf_18 PF12847.2 CEH17131.1 - 2.9e-06 27.8 1.1 3.4e-05 24.3 0.1 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH17131.1 - 5.6e-05 23.1 0.0 0.015 15.2 0.0 2.9 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CEH17131.1 - 0.00081 18.5 0.0 0.0036 16.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 CEH17131.1 - 0.0015 18.2 0.0 0.0049 16.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 CEH17131.1 - 0.0022 17.0 0.0 0.0042 16.0 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.9 CEH17131.1 - 0.017 14.5 0.0 0.079 12.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Arr-ms PF12120.3 CEH17131.1 - 0.029 14.2 0.0 11 5.9 0.0 2.8 2 1 1 3 3 3 0 Rifampin ADP-ribosyl transferase Methyltransf_12 PF08242.7 CEH17131.1 - 0.048 14.1 0.0 0.42 11.1 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 CEH17131.1 - 0.077 12.5 0.0 3.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 CEH17131.1 - 0.24 10.3 0.0 0.4 9.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Mito_carr PF00153.22 CEH17132.1 - 7.9e-15 54.3 0.1 1.4e-06 27.8 0.0 2.4 2 1 0 2 2 2 2 Mitochondrial carrier protein Abhydrolase_3 PF07859.8 CEH17133.1 - 1.4e-21 77.1 0.2 3.8e-18 65.8 0.0 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold COesterase PF00135.23 CEH17133.1 - 0.0003 19.6 0.6 0.00045 19.0 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family DUF2974 PF11187.3 CEH17133.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 CEH17133.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase ICMT PF04140.9 CEH17134.1 - 1.1e-15 57.6 0.6 1.7e-14 53.7 0.1 2.3 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CEH17134.1 - 7.2e-11 42.1 0.9 4e-09 36.5 0.3 2.5 2 0 0 2 2 2 1 Phospholipid methyltransferase SPRY PF00622.23 CEH17136.1 - 1e-05 25.5 0.0 3.1e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 SPRY domain PEMT PF04191.8 CEH17137.1 - 8.2e-19 67.6 0.3 1e-12 48.1 0.0 2.5 2 0 0 2 2 2 2 Phospholipid methyltransferase RhoGAP PF00620.22 CEH17138.1 - 4.4e-43 146.5 0.0 7.3e-43 145.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 CEH17138.1 - 2.4e-07 30.8 0.0 4.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 PH domain PX PF00787.19 CEH17138.1 - 2.8e-07 30.3 0.0 5.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 PX domain PH_11 PF15413.1 CEH17138.1 - 0.035 14.3 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Aldo_ket_red PF00248.16 CEH17139.1 - 1.5e-35 122.4 0.0 4.6e-21 74.8 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family ADH_N PF08240.7 CEH17140.1 - 9.9e-22 76.7 1.8 1.7e-21 76.0 1.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEH17140.1 - 7.3e-19 67.6 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEH17140.1 - 0.0063 15.6 0.2 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 CEH17140.1 - 0.034 14.6 0.2 0.074 13.5 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold RRM_1 PF00076.17 CEH17141.1 - 6.1e-72 237.2 1.4 2.6e-15 55.8 0.0 7.6 5 2 1 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH17141.1 - 1.4e-61 204.3 0.2 2.6e-11 43.3 0.0 6.6 5 1 1 6 6 6 6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH17141.1 - 1.6e-36 123.8 0.0 6.2e-09 35.5 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CEH17141.1 - 0.0001 21.9 5.1 0.043 13.5 0.0 5.5 7 1 1 8 8 8 1 Limkain b1 RRM_2 PF04059.7 CEH17141.1 - 0.1 12.5 0.0 4 7.5 0.0 3.4 4 0 0 4 4 4 0 RNA recognition motif 2 Abhydrolase_2 PF02230.11 CEH17142.1 - 5.7e-28 97.8 0.0 1.6e-18 66.9 0.0 3.0 2 1 1 3 3 3 3 Phospholipase/Carboxylesterase LIP PF03583.9 CEH17144.1 - 8.1e-48 163.0 0.2 1.1e-47 162.6 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase GFA PF04828.9 CEH17145.1 - 0.00031 20.6 0.1 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pro_isomerase PF00160.16 CEH17146.1 - 2.3e-45 154.5 0.4 2.7e-45 154.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltrn_RNA_3 PF02598.12 CEH17147.1 - 1.1e-67 228.4 0.0 1.7e-67 227.8 0.0 1.3 1 1 0 1 1 1 1 Putative RNA methyltransferase Heme_oxygenase PF01126.15 CEH17148.1 - 1.4e-14 54.1 0.0 4.3e-11 42.7 0.0 2.9 2 1 0 2 2 2 2 Heme oxygenase Pkinase PF00069.20 CEH17149.1 - 2.2e-05 23.7 0.0 3.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CEH17149.1 - 0.00011 21.3 0.0 0.00022 20.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEH17149.1 - 0.0045 16.7 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CEH17150.1 - 7.3e-51 172.7 0.0 1e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17150.1 - 8.6e-48 162.6 0.0 1.2e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CEH17150.1 - 0.00021 20.9 1.9 0.00045 19.8 1.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.1 CEH17150.1 - 0.0036 17.2 0.3 0.0089 16.0 0.2 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain APH PF01636.18 CEH17150.1 - 0.0037 17.0 0.0 0.0087 15.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CEH17150.1 - 0.004 16.2 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-HC5HC2H PF13771.1 CEH17150.1 - 0.0043 17.1 1.1 0.0043 17.1 0.8 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD PF00628.24 CEH17150.1 - 0.0082 15.8 4.0 0.019 14.6 2.8 1.6 1 0 0 1 1 1 1 PHD-finger Kinase-like PF14531.1 CEH17150.1 - 0.1 11.5 0.0 0.21 10.4 0.0 1.5 2 0 0 2 2 2 0 Kinase-like C1_3 PF07649.7 CEH17150.1 - 0.1 12.6 4.3 0.26 11.3 3.0 1.7 1 0 0 1 1 1 0 C1-like domain UCR_14kD PF02271.11 CEH17152.1 - 1.6e-34 117.7 1.8 1.8e-34 117.6 1.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit UVR PF02151.14 CEH17152.1 - 0.099 12.1 0.4 0.24 10.9 0.3 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Dus PF01207.12 CEH17153.1 - 6e-62 209.2 0.3 1.5e-61 207.9 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) TPR_11 PF13414.1 CEH17153.1 - 1.3e-07 31.1 6.4 0.0004 19.9 0.6 3.1 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 CEH17153.1 - 0.0028 17.4 6.1 0.056 13.3 0.6 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ThiG PF05690.9 CEH17153.1 - 0.0052 15.8 0.1 0.0052 15.8 0.0 1.6 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG TPR_1 PF00515.23 CEH17153.1 - 0.018 14.6 1.6 0.018 14.6 1.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat His_biosynth PF00977.16 CEH17153.1 - 0.092 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein TPR_12 PF13424.1 CEH17153.1 - 0.82 9.6 8.3 0.82 9.6 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CEH17153.1 - 3.4 8.5 13.8 0.1 13.2 0.8 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AOX PF01786.12 CEH17154.1 - 2.7e-79 265.4 0.1 3.2e-79 265.1 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF221 PF02714.10 CEH17155.1 - 2.9e-88 295.8 20.0 4.5e-88 295.2 13.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CEH17155.1 - 1.4e-31 109.2 3.1 2e-31 108.6 0.0 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CEH17155.1 - 6.9e-07 29.7 0.0 1.8e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) HMA PF00403.21 CEH17156.1 - 2.7e-17 62.6 0.3 3.1e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Zeta_toxin PF06414.7 CEH17159.1 - 0.00038 19.6 0.3 0.00075 18.6 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 CEH17159.1 - 0.00097 19.9 0.0 0.002 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEH17159.1 - 0.0011 18.7 0.1 0.0028 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CEH17159.1 - 0.0049 16.5 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CEH17159.1 - 0.0064 16.4 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.14 CEH17159.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CEH17159.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 CEH17159.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 CEH17159.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CEH17159.1 - 0.031 13.0 0.0 0.067 11.9 0.0 1.6 1 0 0 1 1 1 0 ArgK protein AAA_14 PF13173.1 CEH17159.1 - 0.045 13.6 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CEH17159.1 - 0.072 13.2 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.9 CEH17159.1 - 0.074 12.0 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SRP54 PF00448.17 CEH17159.1 - 0.078 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 CEH17159.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 CEH17159.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 CEH17159.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NMO PF03060.10 CEH17161.1 - 1.4e-44 152.6 2.5 4.6e-44 150.9 1.8 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 CEH17161.1 - 0.0041 16.0 0.2 0.0071 15.2 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase RRM_1 PF00076.17 CEH17164.1 - 7.1e-51 169.7 0.0 1.4e-16 59.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH17164.1 - 9.3e-44 147.2 0.0 2.7e-15 56.0 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH17164.1 - 6.2e-21 74.0 0.0 5e-06 26.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CEH17164.1 - 9.8e-06 25.2 0.0 0.0085 15.8 0.0 3.1 3 0 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 CEH17164.1 - 0.00045 20.0 0.0 2 8.3 0.0 3.1 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.5 CEH17164.1 - 0.002 17.5 0.0 1.5 8.1 0.0 3.4 3 0 0 3 3 3 1 ATP-grasp domain GRP PF07172.6 CEH17164.1 - 0.018 15.5 24.3 0.018 15.5 16.9 3.4 2 1 1 3 3 3 0 Glycine rich protein family Peptidase_M36 PF02128.10 CEH17165.1 - 2.6e-109 365.5 0.2 2.3e-108 362.4 0.1 2.0 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 CEH17165.1 - 0.00017 20.9 0.0 0.00041 19.7 0.0 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Erv26 PF04148.8 CEH17167.1 - 8.4e-06 25.3 0.1 9.4e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 PRA1 PF03208.14 CEH17167.1 - 0.00025 20.4 1.1 0.00028 20.2 0.7 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF2291 PF10054.4 CEH17167.1 - 0.007 15.6 0.0 0.0075 15.5 0.0 1.0 1 0 0 1 1 1 1 Predicted periplasmic lipoprotein (DUF2291) DUF2721 PF11026.3 CEH17167.1 - 0.77 9.4 6.2 2 8.0 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF454 PF04304.8 CEH17167.1 - 1.9 8.6 4.7 1.1 9.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DUF4131 PF13567.1 CEH17167.1 - 1.9 7.8 6.7 3.1 7.1 4.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Y_phosphatase2 PF03162.8 CEH17169.1 - 1.7e-42 144.6 0.0 2e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CEH17169.1 - 9.7e-09 35.6 0.0 3.5e-08 33.8 0.0 1.8 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CEH17169.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ABC_tran PF00005.22 CEH17170.1 - 8.9e-44 149.1 0.0 1.1e-24 87.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CEH17170.1 - 6.4e-20 72.2 0.3 0.00023 21.2 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 CEH17170.1 - 9.9e-15 54.3 0.8 6.1e-05 22.3 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CEH17170.1 - 1.1e-09 37.6 0.2 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CEH17170.1 - 1.7e-07 31.4 0.0 0.031 14.4 0.0 4.8 5 0 0 5 5 5 2 AAA domain AAA_10 PF12846.2 CEH17170.1 - 1.7e-06 27.6 0.2 0.019 14.3 0.0 3.8 3 1 0 3 3 3 2 AAA-like domain AAA_17 PF13207.1 CEH17170.1 - 1.9e-06 28.6 0.6 0.038 14.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 CEH17170.1 - 3.1e-06 26.9 0.0 0.0015 18.3 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit HEAT_EZ PF13513.1 CEH17170.1 - 8.8e-06 26.0 2.0 3.5 8.2 0.0 5.3 3 2 1 4 4 4 0 HEAT-like repeat AAA_15 PF13175.1 CEH17170.1 - 9.9e-06 24.8 0.5 3.4 6.6 0.1 4.3 3 1 0 4 4 4 1 AAA ATPase domain Miro PF08477.8 CEH17170.1 - 1.4e-05 25.5 0.0 0.037 14.5 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 CEH17170.1 - 2.3e-05 24.3 0.3 0.025 14.3 0.2 3.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_23 PF13476.1 CEH17170.1 - 4.1e-05 23.9 10.6 0.055 13.7 0.0 3.9 5 0 0 5 5 3 2 AAA domain NACHT PF05729.7 CEH17170.1 - 4.2e-05 23.2 0.0 0.23 11.0 0.0 2.8 2 0 0 2 2 2 2 NACHT domain HEAT_2 PF13646.1 CEH17170.1 - 7.2e-05 22.9 8.0 0.037 14.3 0.0 4.8 5 1 1 6 6 3 2 HEAT repeats MMR_HSR1 PF01926.18 CEH17170.1 - 9.9e-05 22.2 0.0 0.89 9.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 CEH17170.1 - 0.00016 21.8 0.0 3.3 7.9 0.0 4.9 4 1 1 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CEH17170.1 - 0.00024 21.1 0.0 1.2 9.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CEH17170.1 - 0.00027 20.1 0.0 0.22 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_13 PF13166.1 CEH17170.1 - 0.00034 19.2 0.8 1.1 7.6 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 CEH17170.1 - 0.00053 20.2 2.0 0.098 12.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 CEH17170.1 - 0.00054 18.8 0.1 0.082 11.6 0.0 2.6 2 0 0 2 2 2 1 ArgK protein AAA_33 PF13671.1 CEH17170.1 - 0.00062 19.6 0.0 1.5 8.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CEH17170.1 - 0.00072 19.2 0.1 0.76 9.4 0.1 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CLASP_N PF12348.3 CEH17170.1 - 0.00081 18.8 0.0 0.0035 16.7 0.0 1.9 1 1 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 CEH17170.1 - 0.00087 19.1 1.2 0.24 11.5 0.0 4.6 5 0 0 5 5 4 1 HEAT repeat Chromo PF00385.19 CEH17170.1 - 0.0013 18.3 0.6 0.0034 17.0 0.0 2.1 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain RNA_helicase PF00910.17 CEH17170.1 - 0.0013 18.8 0.0 2.1 8.5 0.0 3.0 3 0 0 3 3 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 CEH17170.1 - 0.0013 18.2 0.0 1.5 8.2 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family NB-ARC PF00931.17 CEH17170.1 - 0.0033 16.3 0.2 2 7.2 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_5 PF07728.9 CEH17170.1 - 0.007 16.1 3.2 13 5.5 0.0 4.8 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CEH17170.1 - 0.0086 16.0 9.3 0.064 13.2 0.4 4.6 3 2 1 4 4 4 1 AAA ATPase domain AAA_25 PF13481.1 CEH17170.1 - 0.011 15.1 0.0 2.7 7.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain DUF815 PF05673.8 CEH17170.1 - 0.019 13.8 0.2 3.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 CEH17170.1 - 0.027 14.3 0.0 4.2 7.2 0.0 3.5 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 CEH17170.1 - 0.049 13.3 0.0 6.3 6.4 0.0 2.6 2 0 0 2 2 2 0 NTPase G-alpha PF00503.15 CEH17170.1 - 0.053 12.1 6.9 0.87 8.2 0.0 2.8 3 0 0 3 3 2 0 G-protein alpha subunit cobW PF02492.14 CEH17170.1 - 0.054 12.9 0.1 11 5.3 0.0 2.9 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2435 PF10363.4 CEH17170.1 - 0.062 13.2 0.1 0.3 10.9 0.0 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF2435) MutS_V PF00488.16 CEH17170.1 - 0.085 12.2 0.2 12 5.2 0.0 2.3 2 0 0 2 2 2 0 MutS domain V ATP_bind_1 PF03029.12 CEH17170.1 - 0.11 12.0 0.1 9.4 5.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 CEH17170.1 - 0.2 11.4 1.7 3.5 7.4 0.0 3.0 3 0 0 3 3 2 0 Dynamin family Arch_ATPase PF01637.13 CEH17170.1 - 1.1 8.9 10.0 2.5 7.7 0.2 4.1 5 1 0 5 5 3 0 Archaeal ATPase AFG1_ATPase PF03969.11 CEH17171.1 - 3e-86 289.4 0.0 2.4e-58 197.6 0.0 2.7 3 0 0 3 3 3 2 AFG1-like ATPase AAA_22 PF13401.1 CEH17171.1 - 0.0013 18.9 0.0 0.0081 16.3 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CEH17171.1 - 0.005 16.8 0.0 0.018 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 CEH17171.1 - 0.012 14.7 0.1 0.023 13.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CEH17171.1 - 0.023 14.9 0.0 0.11 12.7 0.0 2.1 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CEH17171.1 - 0.026 14.0 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 CEH17171.1 - 0.059 13.0 0.0 0.25 11.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CEH17171.1 - 0.08 13.1 0.1 0.77 9.9 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 CEH17171.1 - 0.099 12.2 0.3 10 5.6 0.0 2.6 3 0 0 3 3 3 0 Bacterial dnaA protein DUF2075 PF09848.4 CEH17171.1 - 0.14 11.0 0.0 0.31 9.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 CEH17171.1 - 0.16 12.1 0.1 0.69 10.1 0.0 2.3 2 0 0 2 2 1 0 RNA helicase SRP9-21 PF05486.7 CEH17172.1 - 1.1e-12 47.5 0.1 1.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) PAH PF02671.16 CEH17176.1 - 3.5e-45 151.3 3.1 5e-18 64.4 0.5 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CEH17176.1 - 9.5e-33 111.9 1.9 2.2e-32 110.7 0.2 2.4 3 0 0 3 3 3 1 Sin3 family co-repressor Hus1 PF04005.7 CEH17177.1 - 1e-67 228.1 0.3 1.2e-67 227.9 0.2 1.1 1 0 0 1 1 1 1 Hus1-like protein Noelin-1 PF12308.3 CEH17177.1 - 0.056 13.2 0.1 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein SpoVIF PF14069.1 CEH17177.1 - 0.071 12.8 0.1 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Stage VI sporulation protein F Agglutinin PF07468.6 CEH17177.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Agglutinin Peptidase_M16 PF00675.15 CEH17177.1 - 0.098 12.4 0.1 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) FAM24 PF15193.1 CEH17179.1 - 0.07 13.3 1.2 0.073 13.2 0.8 1.2 1 0 0 1 1 1 0 FAM24 family HAD_2 PF13419.1 CEH17180.1 - 4.5e-25 88.8 0.7 2.3e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEH17180.1 - 1.3e-07 31.2 0.0 2.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like GTP_EFTU PF00009.22 CEH17181.1 - 5.6e-49 166.1 0.0 9.8e-49 165.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CEH17181.1 - 5.7e-40 135.5 0.2 1.2e-39 134.5 0.2 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CEH17181.1 - 1e-15 57.3 0.0 2.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 CEH17181.1 - 2.2e-06 27.5 0.0 4.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CEH17181.1 - 7.6e-05 22.7 0.1 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CEH17181.1 - 0.00025 20.8 0.0 0.00066 19.4 0.0 1.7 1 1 0 1 1 1 1 Elongation Factor G, domain II AIG1 PF04548.11 CEH17181.1 - 0.0031 16.6 0.0 0.006 15.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 CEH17181.1 - 0.0062 17.0 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CEH17181.1 - 0.046 13.1 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 Ras family Cu-oxidase_3 PF07732.10 CEH17182.1 - 2.3e-31 107.9 1.3 1.2e-30 105.6 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 CEH17182.1 - 6.4e-22 78.1 0.0 3.4e-21 75.7 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CEH17182.1 - 3e-11 43.0 3.7 8.1e-07 28.6 0.1 3.4 2 1 0 2 2 2 2 Multicopper oxidase MARVEL PF01284.18 CEH17186.1 - 0.00015 21.5 12.0 0.00018 21.3 8.0 1.3 1 1 0 1 1 1 1 Membrane-associating domain Peptidase_M90 PF06167.7 CEH17188.1 - 0.022 14.1 0.3 0.04 13.2 0.2 1.4 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 CM_2 PF01817.16 CEH17189.1 - 1.5e-07 31.4 0.1 1.9e-05 24.6 0.0 3.2 2 1 0 2 2 2 2 Chorismate mutase type II SGS PF05002.10 CEH17190.1 - 4e-28 96.9 1.7 9.5e-28 95.7 1.2 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.11 CEH17190.1 - 2.9e-13 50.1 0.1 4.6e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 CS domain DPBB_1 PF03330.13 CEH17191.1 - 6.6e-11 42.0 0.4 4.8e-10 39.2 0.1 2.6 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF605 PF04652.11 CEH17191.1 - 0.0075 15.7 22.9 0.0089 15.4 15.9 1.1 1 0 0 1 1 1 1 Vta1 like DUF572 PF04502.8 CEH17191.1 - 0.11 11.6 26.2 0.15 11.2 18.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.4 CEH17191.1 - 1.5 7.0 16.5 2.1 6.5 11.5 1.3 1 0 0 1 1 1 0 Transmembrane protein PAT1 PF09770.4 CEH17191.1 - 2.3 6.3 28.2 2.9 6.0 19.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nop14 PF04147.7 CEH17191.1 - 2.8 5.7 24.1 3.5 5.4 16.7 1.0 1 0 0 1 1 1 0 Nop14-like family XRCC4 PF06632.7 CEH17191.1 - 3.7 6.3 18.5 5.6 5.7 12.8 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF1675 PF07897.6 CEH17191.1 - 3.7 7.3 19.1 5.7 6.7 13.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CDC45 PF02724.9 CEH17191.1 - 4.7 5.1 21.7 6.1 4.7 15.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.10 CEH17191.1 - 8.5 5.5 23.9 11 5.1 16.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pneumo_att_G PF05539.6 CEH17193.1 - 4.6 6.5 6.0 7 5.9 4.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Aa_trans PF01490.13 CEH17194.1 - 7e-81 271.7 33.5 8.8e-81 271.4 23.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TarH PF02203.10 CEH17194.1 - 0.3 10.8 0.8 0.9 9.3 0.6 1.7 1 0 0 1 1 1 0 Tar ligand binding domain homologue Sugar_tr PF00083.19 CEH17195.1 - 1.4e-102 343.6 20.9 1.6e-102 343.3 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH17195.1 - 3e-22 78.8 33.5 2.9e-14 52.5 9.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily PSP1 PF04468.7 CEH17196.1 - 0.0064 16.4 0.0 6.6 6.7 0.0 2.7 2 0 0 2 2 2 2 PSP1 C-terminal conserved region GATA PF00320.22 CEH17198.1 - 4.4e-14 51.5 3.4 4.4e-14 51.5 2.3 2.3 2 0 0 2 2 2 1 GATA zinc finger PAS_3 PF08447.6 CEH17198.1 - 1.5e-10 40.9 0.0 3.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 CEH17198.1 - 5.7e-06 26.3 0.0 2.1e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 CEH17198.1 - 6.8e-06 25.8 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 CEH17198.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_11 PF14598.1 CEH17198.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain TF_Zn_Ribbon PF08271.7 CEH17198.1 - 0.093 12.0 0.7 0.36 10.1 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding RRN7 PF11781.3 CEH17198.1 - 0.12 11.8 0.9 4.4 6.9 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 UreF PF01730.11 CEH17199.1 - 8.2e-13 48.7 0.0 1.9e-12 47.5 0.0 1.6 1 1 0 1 1 1 1 UreF zf-DHHC PF01529.15 CEH17200.1 - 1.6e-33 115.5 0.1 5.2e-33 113.8 0.0 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase zf-tcix PF14952.1 CEH17200.1 - 0.089 12.1 2.8 0.16 11.2 1.9 1.4 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Mito_carr PF00153.22 CEH17202.1 - 1e-12 47.5 0.3 7.8e-06 25.5 0.0 4.2 4 0 0 4 4 4 2 Mitochondrial carrier protein Herpes_LMP1 PF05297.6 CEH17202.1 - 0.57 9.0 5.3 1.1 8.0 3.7 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Chalcone PF02431.10 CEH17203.1 - 2.3e-36 125.0 0.0 3.9e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Chalcone-flavanone isomerase ubiquitin PF00240.18 CEH17204.1 - 9.9e-11 40.8 0.0 1.2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CEH17204.1 - 9.8e-05 22.5 0.0 0.00031 20.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 CEH17204.1 - 0.00017 21.1 0.0 0.00019 21.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 CEH17204.1 - 0.02 15.1 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 EnY2 PF10163.4 CEH17205.1 - 4.7e-13 48.8 0.0 5.6e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 TPR_14 PF13428.1 CEH17205.1 - 0.095 13.3 0.8 0.3 11.8 0.4 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat DSBA PF01323.15 CEH17205.1 - 0.11 12.0 0.6 0.14 11.7 0.4 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain RecO_C PF02565.10 CEH17205.1 - 0.13 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal XK-related PF09815.4 CEH17205.1 - 0.16 10.9 0.0 0.17 10.8 0.0 1.0 1 0 0 1 1 1 0 XK-related protein Histone PF00125.19 CEH17206.1 - 6.1e-31 106.3 0.0 8.9e-31 105.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CEH17206.1 - 0.0027 17.8 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CEH17206.1 - 0.0065 15.7 0.1 0.01 15.0 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 CEH17206.1 - 0.026 14.5 0.3 0.1 12.6 0.1 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PP2C PF00481.16 CEH17207.1 - 3.6e-34 118.3 0.0 4.3e-31 108.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C DUF3445 PF11927.3 CEH17208.1 - 5.9e-47 160.1 0.0 8.1e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Metal_resist PF13801.1 CEH17210.1 - 0.019 14.9 0.0 0.094 12.7 0.0 2.0 2 0 0 2 2 2 0 Heavy-metal resistance 2OG-FeII_Oxy_3 PF13640.1 CEH17210.1 - 0.04 14.4 0.0 0.077 13.5 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF1479 PF07350.7 CEH17211.1 - 3.3e-132 440.9 0.0 5.9e-132 440.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1479) FAD_binding_4 PF01565.18 CEH17212.1 - 1.8e-23 82.5 0.1 3.4e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain N6-adenineMlase PF10237.4 CEH17213.1 - 1.2e-33 116.0 0.0 1.9e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase TATR PF03430.8 CEH17213.1 - 0.059 12.0 5.6 0.077 11.6 3.9 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF572 PF04502.8 CEH17213.1 - 3.1 6.9 11.1 4.6 6.3 7.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) FLO_LFY PF01698.11 CEH17213.1 - 3.7 6.2 8.6 5.1 5.8 6.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Aa_trans PF01490.13 CEH17214.1 - 1.9e-59 201.1 6.0 2.4e-59 200.8 4.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2107 PF09880.4 CEH17214.1 - 0.0018 18.1 1.1 0.16 11.8 0.0 2.9 2 0 0 2 2 2 2 Predicted membrane protein (DUF2107) SET PF00856.23 CEH17215.1 - 2.3e-05 24.7 0.0 8.2e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 SET domain Pkinase PF00069.20 CEH17216.1 - 3.9e-67 226.1 0.0 4.7e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17216.1 - 5.8e-33 114.0 0.0 7.4e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH17216.1 - 0.00048 19.1 0.0 0.0011 18.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEH17216.1 - 0.0019 17.3 0.2 0.013 14.6 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEH17216.1 - 0.0028 17.4 0.3 0.015 15.0 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family YukC PF10140.4 CEH17216.1 - 0.084 11.4 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Acid_PPase PF12689.2 CEH17217.1 - 4.1e-57 192.5 0.0 5e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase SMI1_KNR4 PF09346.5 CEH17218.1 - 3.1e-26 91.9 0.0 8.5e-26 90.4 0.0 1.7 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) DUF2442 PF10387.4 CEH17218.1 - 0.066 13.2 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) EAF PF09816.4 CEH17220.1 - 1.9e-11 43.8 0.0 4.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Uds1 PF15456.1 CEH17221.1 - 3.9e-18 65.6 2.4 3.9e-18 65.6 1.6 9.6 4 2 4 8 8 8 3 Up-regulated During Septation Mpv17_PMP22 PF04117.7 CEH17222.1 - 9.4e-08 31.5 0.2 1.1e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3337 PF11816.3 CEH17224.1 - 1.8e-54 185.3 0.0 3.3e-53 181.2 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 CEH17224.1 - 7.9e-24 82.6 24.9 6.3e-09 35.3 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CEH17224.1 - 0.0041 15.9 0.5 0.53 8.9 0.2 3.0 2 1 1 3 3 3 1 Nup133 N terminal like RPAP2_Rtr1 PF04181.8 CEH17225.1 - 1.5e-08 34.5 0.2 4.4e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 Rtr1/RPAP2 family Flu_M1_C PF08289.6 CEH17225.1 - 0.24 11.4 2.9 3 7.9 0.1 2.9 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain SpoIIE PF07228.7 CEH17226.1 - 1.4e-07 31.4 0.0 8.7e-07 28.8 0.0 2.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CEH17226.1 - 2.1e-06 27.2 0.0 9.4e-06 25.1 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CEH17226.1 - 0.00038 19.9 0.0 0.003 17.0 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C G6PD_C PF02781.11 CEH17227.1 - 6.5e-114 379.7 0.0 8.5e-114 379.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CEH17227.1 - 2e-61 207.4 0.0 2.8e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Tubulin PF00091.20 CEH17228.1 - 5.8e-69 232.2 0.0 9.4e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CEH17228.1 - 2.6e-54 182.6 0.4 2.9e-39 133.9 0.1 2.3 1 1 1 2 2 2 2 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CEH17228.1 - 4e-06 26.8 0.0 9.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CEH17228.1 - 0.0017 17.8 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Zn_clus PF00172.13 CEH17230.1 - 3.2e-06 26.9 7.9 5.2e-06 26.2 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.22 CEH17231.1 - 2e-59 200.2 0.4 2.9e-59 199.6 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CEH17231.1 - 2.3e-24 85.4 0.0 5.6e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CEH17231.1 - 6.6e-15 54.9 3.5 9.4e-15 54.4 1.7 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEH17231.1 - 4e-05 23.5 0.1 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CEH17231.1 - 0.00028 20.4 0.1 0.00064 19.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 CEH17231.1 - 0.001 19.5 0.1 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CEH17231.1 - 0.027 13.9 0.3 8 5.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CEH17231.1 - 0.053 12.9 1.3 0.06 12.7 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sec61_beta PF03911.11 CEH17232.1 - 2.1e-16 59.4 0.5 2.9e-16 58.9 0.3 1.2 1 0 0 1 1 1 1 Sec61beta family Methyltransf_11 PF08241.7 CEH17235.1 - 4.7e-21 75.0 0.0 7.8e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH17235.1 - 1.9e-17 63.2 0.0 2.4e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH17235.1 - 1.1e-12 48.2 0.0 1.8e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEH17235.1 - 3.2e-12 46.0 0.0 4.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CEH17235.1 - 1.9e-11 44.2 0.0 3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH17235.1 - 3.3e-10 39.9 0.0 4.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH17235.1 - 6.8e-10 39.5 0.0 1.3e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH17235.1 - 1.6e-06 28.1 0.0 4.8e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 CEH17235.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.10 CEH17235.1 - 0.032 13.8 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase MTS PF05175.9 CEH17235.1 - 0.053 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.11 CEH17235.1 - 0.057 11.7 0.0 0.077 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NNMT_PNMT_TEMT PF01234.12 CEH17235.1 - 0.18 10.7 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MDMPI_N PF11716.3 CEH17236.1 - 0.26 11.7 3.2 0.31 11.4 2.2 1.1 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain SARS_X4 PF08779.5 CEH17237.1 - 0.051 13.7 0.1 6.6 6.9 0.0 2.8 3 0 0 3 3 3 0 SARS coronavirus X4 like DUF2422 PF10337.4 CEH17238.1 - 3.9e-73 246.8 4.1 2.4e-72 244.2 1.5 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 CEH17238.1 - 2.2e-44 151.7 0.0 3.8e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 CEH17238.1 - 1.4e-09 37.9 14.0 1.4e-09 37.9 9.7 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like Fe-ADH PF00465.14 CEH17239.1 - 1.6e-92 310.0 0.0 2e-92 309.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CEH17239.1 - 2e-11 43.6 0.0 4.5e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Lactamase_B PF00753.22 CEH17240.1 - 1.3e-12 47.8 0.8 4.5e-12 46.0 0.5 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CEH17240.1 - 0.00012 21.7 0.1 0.00014 21.4 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_5 PF12695.2 CEH17241.1 - 6.4e-08 32.4 0.2 7.1e-07 29.0 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CEH17241.1 - 3.3e-07 30.1 0.0 6.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 CEH17241.1 - 7.8e-06 25.3 0.0 1.7e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 CEH17241.1 - 0.00047 19.7 0.0 0.00086 18.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CEH17241.1 - 0.00066 19.9 1.2 0.0053 17.0 0.0 2.7 3 0 0 3 3 3 1 Thioesterase domain DUF915 PF06028.6 CEH17241.1 - 0.00089 18.4 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 CEH17241.1 - 0.0094 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase p450 PF00067.17 CEH17242.1 - 6e-55 186.6 0.0 7.4e-41 140.1 0.2 3.1 2 1 0 2 2 2 2 Cytochrome P450 DUF676 PF05057.9 CEH17243.1 - 1.3e-05 24.5 0.0 2.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CEH17243.1 - 4.5e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CEH17243.1 - 0.0003 20.5 0.0 0.0003 20.5 0.0 2.8 3 1 0 3 3 3 1 Alpha/beta hydrolase family FMN_red PF03358.10 CEH17244.1 - 1.7e-10 40.6 0.2 2.9e-10 39.8 0.0 1.4 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CEH17244.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 CEH17244.1 - 0.0044 17.0 0.1 0.01 15.8 0.1 1.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 CEH17244.1 - 0.085 12.8 0.0 0.25 11.3 0.0 1.9 2 1 1 3 3 3 0 Flavodoxin domain ORC6 PF05460.8 CEH17247.1 - 0.00015 20.9 25.5 0.065 12.3 17.7 2.1 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Nucleo_P87 PF07267.6 CEH17247.1 - 0.42 9.2 3.4 0.57 8.8 2.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SBDS PF01172.13 CEH17249.1 - 6e-15 54.8 0.0 7.4e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein L27_N PF09060.5 CEH17249.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 L27_N IU_nuc_hydro PF01156.14 CEH17250.1 - 7.8e-33 114.0 0.1 1.2e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ADH_N PF08240.7 CEH17251.1 - 5.7e-22 77.5 3.6 1.8e-21 75.9 2.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEH17251.1 - 2.9e-15 55.9 0.0 6e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH17251.1 - 5.1e-06 27.4 0.0 1.3e-05 26.0 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEH17251.1 - 0.003 16.7 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 CEH17251.1 - 0.0051 17.1 0.0 0.21 11.9 0.0 2.3 2 0 0 2 2 2 1 XdhC Rossmann domain Methyltransf_18 PF12847.2 CEH17251.1 - 0.033 14.7 0.0 0.069 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Saccharop_dh PF03435.13 CEH17253.1 - 1.2e-104 350.4 0.0 2.4e-104 349.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 CEH17253.1 - 5.2e-85 284.3 0.0 8.4e-85 283.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Semialdhyde_dh PF01118.19 CEH17253.1 - 9e-05 22.7 0.6 0.0018 18.5 0.0 3.1 3 1 1 4 4 4 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CEH17253.1 - 0.0001 22.3 0.2 0.00063 19.8 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 CEH17253.1 - 0.00045 20.3 0.2 0.0094 16.0 0.1 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_12 PF08242.7 CEH17253.1 - 0.011 16.2 0.0 1.5 9.3 0.0 3.1 2 1 0 2 2 2 0 Methyltransferase domain F420_oxidored PF03807.12 CEH17253.1 - 0.041 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_2 PF00891.13 CEH17253.1 - 0.047 12.8 0.1 0.087 11.9 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_18 PF12847.2 CEH17253.1 - 0.09 13.3 0.0 0.37 11.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain TFIIF_beta PF02270.10 CEH17255.1 - 1.6e-50 172.5 0.0 2.2e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 CEH17255.1 - 0.0045 16.3 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Tyr-DNA_phospho PF06087.7 CEH17256.1 - 6.8e-32 110.6 0.0 9.8e-24 83.7 0.0 3.0 3 1 0 3 3 3 2 Tyrosyl-DNA phosphodiesterase PITH PF06201.8 CEH17257.1 - 3e-38 130.9 0.0 3.5e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 PITH domain MoaE PF02391.12 CEH17258.1 - 1.5e-26 92.4 0.0 5.3e-26 90.7 0.0 1.7 1 1 0 1 1 1 1 MoaE protein DUF1275 PF06912.6 CEH17262.1 - 9.3e-24 83.7 9.7 4.4e-23 81.5 1.3 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1275) F1F0-ATPsyn_F PF10791.4 CEH17263.1 - 0.12 12.6 0.1 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Pkinase PF00069.20 CEH17265.1 - 1.6e-39 135.6 0.0 2.2e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17265.1 - 3.9e-30 104.8 0.0 4.9e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH17265.1 - 0.0005 19.8 0.0 0.55 9.9 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CEH17265.1 - 0.0011 18.0 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEH17265.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NicO PF03824.11 CEH17267.1 - 1.6e-36 126.1 14.1 4.2e-36 124.7 1.3 2.9 4 0 0 4 4 4 2 High-affinity nickel-transport protein DUF624 PF04854.9 CEH17267.1 - 0.029 14.2 0.6 0.29 11.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF624 DUF4231 PF14015.1 CEH17267.1 - 0.088 12.8 8.3 0.48 10.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF4557 PF15101.1 CEH17267.1 - 0.12 12.2 0.7 13 5.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Ecl1 PF12855.2 CEH17268.1 - 0.00039 19.6 0.0 1 8.6 0.0 2.4 2 0 0 2 2 2 2 Life-span regulatory factor DUF329 PF03884.9 CEH17268.1 - 0.019 14.4 0.2 0.055 13.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF329) Aminotran_1_2 PF00155.16 CEH17269.1 - 2.5e-44 151.7 0.0 3.2e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CEH17269.1 - 0.00072 18.7 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 CEH17269.1 - 0.01 14.7 0.0 0.024 13.4 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-III Aldo_ket_red PF00248.16 CEH17270.1 - 3.1e-56 190.2 0.1 3.7e-56 190.0 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FAT PF02259.18 CEH17271.1 - 8.5e-72 242.0 8.7 2e-71 240.8 6.0 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CEH17271.1 - 7e-21 74.7 0.0 1.7e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CEH17271.1 - 0.0059 16.0 0.1 0.016 14.6 0.1 1.8 1 0 0 1 1 1 1 FATC domain PI3_PI4_kinase PF00454.22 CEH17272.1 - 2.2e-34 118.9 0.0 3.7e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 CEH17272.1 - 0.0077 15.9 2.9 0.026 14.2 2.0 1.9 1 1 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 CEH17272.1 - 0.0095 15.1 0.1 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 CEH17272.1 - 0.094 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DcpS_C PF11969.3 CEH17273.1 - 1.7e-14 54.0 1.3 1.3e-13 51.1 0.9 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CEH17273.1 - 2.5e-06 27.9 3.0 2.5e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 HIT domain FR47 PF08445.5 CEH17273.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein RNase_T PF00929.19 CEH17274.1 - 3e-26 92.6 0.0 3.7e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF2390 PF09523.5 CEH17274.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Calpain_III PF01067.17 CEH17275.1 - 6.6e-23 80.9 0.0 6.4e-12 45.3 0.0 4.7 3 2 0 3 3 3 3 Calpain large subunit, domain III Peptidase_C2 PF00648.16 CEH17275.1 - 4.7e-09 35.6 0.0 8.5e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 CEH17275.1 - 0.0077 16.0 0.5 0.015 15.1 0.4 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain CRCB PF02537.10 CEH17276.1 - 2.8e-21 75.5 19.8 3.1e-14 52.8 6.2 2.7 3 0 0 3 3 3 2 CrcB-like protein Colicin_V PF02674.11 CEH17276.1 - 1.5 8.6 7.5 1.1 9.1 0.1 2.8 2 1 1 3 3 3 0 Colicin V production protein LON PF02190.11 CEH17277.1 - 2.4e-21 76.3 0.0 1e-20 74.3 0.0 2.0 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 CEH17277.1 - 3.8e-06 26.6 3.2 7.9e-06 25.6 2.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CEH17277.1 - 1.3e-05 24.6 3.1 2.5e-05 23.8 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH17277.1 - 3.4e-05 23.7 3.4 7.7e-05 22.6 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEH17277.1 - 0.00024 20.7 4.6 0.00047 19.7 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEH17277.1 - 0.00045 19.9 4.6 0.0013 18.5 3.2 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 CEH17277.1 - 0.0098 15.6 1.7 0.02 14.6 1.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CEH17277.1 - 0.25 11.0 2.5 0.52 10.0 1.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 CEH17277.1 - 0.34 10.6 8.0 0.69 9.6 5.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF35_N PF12172.3 CEH17277.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) IPK PF03770.11 CEH17278.1 - 1.1e-50 172.0 0.0 1.7e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Alpha-L-AF_C PF06964.7 CEH17279.1 - 4.3e-30 104.7 0.2 9.4e-30 103.6 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus IF3_N PF05198.11 CEH17280.1 - 2.2e-05 24.2 0.4 4e-05 23.4 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain DUF849 PF05853.7 CEH17280.1 - 0.007 15.2 0.0 0.13 11.1 0.1 2.0 2 0 0 2 2 2 1 Prokaryotic protein of unknown function (DUF849) DUF3104 PF11302.3 CEH17280.1 - 0.024 13.9 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Abhydrolase_3 PF07859.8 CEH17281.1 - 2.4e-15 56.7 0.1 8.2e-12 45.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH17281.1 - 4.1e-13 49.3 0.0 8.7e-13 48.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH17281.1 - 8.8e-12 45.3 0.2 1.2e-11 44.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEH17281.1 - 1.5e-08 34.1 0.3 9.8e-05 21.6 0.0 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CEH17281.1 - 0.0015 17.9 0.0 0.0044 16.4 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 CEH17281.1 - 0.0035 16.6 0.0 0.046 13.0 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Propep_M14 PF02244.11 CEH17281.1 - 0.16 11.6 0.0 0.55 9.9 0.0 1.8 2 0 0 2 2 2 0 Carboxypeptidase activation peptide Melibiase PF02065.13 CEH17282.1 - 5e-09 35.3 0.0 0.0002 20.1 0.0 2.1 1 1 1 2 2 2 2 Melibiase Macoilin PF09726.4 CEH17283.1 - 0.0052 15.1 6.5 0.0058 14.9 4.5 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF4614 PF15391.1 CEH17283.1 - 0.051 13.3 7.3 0.094 12.4 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) FancD2 PF14631.1 CEH17283.1 - 0.17 8.9 1.5 0.21 8.6 1.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Apt1 PF10351.4 CEH17283.1 - 0.19 10.5 9.9 0.25 10.1 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BicD PF09730.4 CEH17283.1 - 0.5 8.6 2.1 0.66 8.2 1.5 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF2217 PF10265.4 CEH17283.1 - 1.1 7.9 10.2 1.4 7.5 7.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Secretin_N_2 PF07655.8 CEH17283.1 - 1.6 9.1 18.4 2.9 8.3 12.8 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DNA_pol_viral_N PF00242.12 CEH17283.1 - 1.9 7.4 10.2 2.3 7.1 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SR-25 PF10500.4 CEH17283.1 - 3.3 7.1 35.9 6 6.2 24.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hepatitis_core PF00906.15 CEH17283.1 - 6.8 6.3 11.8 13 5.4 8.2 1.4 1 0 0 1 1 1 0 Hepatitis core antigen CorA PF01544.13 CEH17284.1 - 9.5e-19 67.5 3.7 2.5e-08 33.2 0.3 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein RAMP PF04901.8 CEH17284.1 - 0.25 11.0 0.2 0.49 10.1 0.1 1.3 1 0 0 1 1 1 0 Receptor activity modifying family Glyco_hydro_32N PF00251.15 CEH17286.1 - 2e-83 280.2 5.2 2.8e-83 279.8 3.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CEH17286.1 - 8.7e-05 22.8 0.0 0.0023 18.2 0.0 2.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Coatomer_WDAD PF04053.9 CEH17288.1 - 3.5e-139 464.4 0.0 5.8e-139 463.6 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CEH17288.1 - 6.4e-80 268.7 0.0 9.2e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CEH17288.1 - 1.5e-54 180.0 7.6 9.8e-11 41.1 0.0 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.3 CEH17288.1 - 0.021 12.9 4.5 0.16 10.0 0.0 3.1 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Clathrin PF00637.15 CEH17288.1 - 0.22 11.1 0.0 0.8 9.3 0.0 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_2 PF07719.12 CEH17288.1 - 0.24 11.4 1.8 5.5 7.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_90 PF05686.7 CEH17291.1 - 3.2e-24 85.3 0.0 6.2e-24 84.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 T_cell_tran_alt PF15128.1 CEH17291.1 - 0.022 14.1 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered MARVEL PF01284.18 CEH17293.1 - 2.4e-06 27.4 5.8 4.1e-06 26.6 4.0 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF973 PF06157.6 CEH17293.1 - 0.11 11.5 8.4 0.15 10.9 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF4013 PF13197.1 CEH17293.1 - 0.13 11.5 10.8 5.8 6.2 6.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) WD40 PF00400.27 CEH17294.1 - 2.9e-07 30.0 12.0 0.036 13.9 0.1 5.6 6 1 0 6 6 6 3 WD domain, G-beta repeat Sugar_tr PF00083.19 CEH17295.1 - 1.5e-111 373.2 20.9 1.7e-111 373.0 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH17295.1 - 1.9e-18 66.3 37.1 1.9e-18 66.3 25.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.6 CEH17296.1 - 8.9e-11 41.6 0.0 3.8e-10 39.6 0.0 2.1 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CEH17296.1 - 3.6e-05 23.8 0.0 8.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Lactamase_B PF00753.22 CEH17297.1 - 1.4e-05 24.8 3.1 0.0096 15.5 0.8 2.8 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CEH17297.1 - 0.0032 17.0 0.1 0.0044 16.5 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-HIT PF04438.11 CEH17298.1 - 1.8e-05 24.2 10.6 1.8e-05 24.2 7.3 1.6 2 0 0 2 2 2 1 HIT zinc finger zf-B_box PF00643.19 CEH17298.1 - 2.4 8.1 8.6 4.8 7.1 6.0 1.4 1 0 0 1 1 1 0 B-box zinc finger DWNN PF08783.6 CEH17299.1 - 1.3e-26 92.3 0.0 2.3e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 CEH17299.1 - 6.4e-06 25.5 2.7 1.7e-05 24.2 1.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CEH17299.1 - 0.00037 20.2 2.5 0.00092 19.0 1.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CEH17299.1 - 0.00084 19.0 0.4 0.00084 19.0 0.3 1.9 2 0 0 2 2 2 1 Zinc knuckle Dehydrin PF00257.14 CEH17299.1 - 0.038 14.3 0.7 0.038 14.3 0.5 2.6 3 0 0 3 3 3 0 Dehydrin zf-RING_2 PF13639.1 CEH17299.1 - 0.076 12.8 10.6 0.16 11.8 7.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 CEH17299.1 - 0.29 11.0 12.4 0.65 9.9 8.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CEH17299.1 - 1.6 8.7 19.5 0.027 14.4 8.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH17299.1 - 2.3 7.9 13.0 4.1 7.1 9.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rer1 PF03248.8 CEH17300.1 - 1e-75 253.2 0.0 1.2e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Rer1 family EI24 PF07264.6 CEH17300.1 - 0.44 9.9 8.2 5.1 6.4 5.7 2.0 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4131 PF13567.1 CEH17300.1 - 0.95 8.8 5.9 2 7.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_M1 PF01433.15 CEH17301.1 - 3.5e-50 171.2 0.0 1.2e-49 169.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 CEH17301.1 - 2.4e-37 127.7 0.1 3.7e-37 127.0 0.1 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 CEH17301.1 - 5.6e-12 45.8 0.0 1.2e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Aldedh PF00171.17 CEH17302.1 - 1.4e-120 402.7 0.1 2.1e-120 402.1 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Prenyltrans_1 PF13243.1 CEH17304.1 - 2.5e-27 95.0 1.0 2.4e-17 62.9 0.0 5.7 3 3 3 6 6 6 4 Prenyltransferase-like Prenyltrans PF00432.16 CEH17304.1 - 1e-26 92.1 13.1 4e-08 32.6 0.2 6.5 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CEH17304.1 - 1.1e-24 87.0 2.2 1.2e-10 41.8 0.0 4.9 2 2 2 4 4 4 4 Prenyltransferase-like Pec_lyase PF09492.5 CEH17304.1 - 1.3e-06 27.8 0.0 0.092 11.9 0.0 4.2 2 1 2 4 4 4 2 Pectic acid lyase A2M_comp PF07678.9 CEH17304.1 - 2.5e-05 23.6 0.0 0.18 11.0 0.0 4.8 3 1 2 5 5 5 1 A-macroglobulin complement component AAA_2 PF07724.9 CEH17305.1 - 1.4e-16 60.9 0.0 4.5e-13 49.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CEH17305.1 - 1.1e-09 38.5 0.0 2.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CEH17305.1 - 4.6e-06 26.7 0.3 1.3e-05 25.2 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CEH17305.1 - 6.6e-05 22.6 0.2 0.00019 21.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CEH17305.1 - 7.9e-05 22.1 0.2 0.00017 21.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEH17305.1 - 9.7e-05 22.2 0.1 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CEH17305.1 - 0.00014 22.6 0.0 0.00027 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEH17305.1 - 0.00037 20.6 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CEH17305.1 - 0.00084 18.5 2.7 0.29 10.2 0.2 3.0 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 CEH17305.1 - 0.0059 16.2 0.4 0.011 15.3 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH17305.1 - 0.0067 16.1 1.6 0.012 15.3 0.4 2.0 2 1 0 2 2 1 1 Part of AAA domain ABC_tran PF00005.22 CEH17305.1 - 0.0086 16.3 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 CEH17305.1 - 0.015 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CEH17305.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 CEH17305.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CEH17305.1 - 0.021 14.3 0.0 0.21 11.0 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain MCM PF00493.18 CEH17305.1 - 0.028 13.2 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family Zeta_toxin PF06414.7 CEH17305.1 - 0.029 13.4 0.0 0.078 12.0 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 CEH17305.1 - 0.04 13.4 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 CEH17305.1 - 0.042 13.3 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 CEH17305.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 CEH17305.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.12 CEH17305.1 - 0.085 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_10 PF12846.2 CEH17305.1 - 0.085 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ClpB_D2-small PF10431.4 CEH17305.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_3 PF07726.6 CEH17305.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CEH17305.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 CEH17305.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein TIP49 PF06068.8 CEH17305.1 - 0.23 10.1 0.0 0.34 9.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus YCII PF03795.9 CEH17307.1 - 2.3e-06 27.7 0.0 6.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 YCII-related domain Complex1_49kDa PF00346.14 CEH17308.1 - 1.8e-126 420.7 0.0 2.3e-126 420.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 CEH17308.1 - 0.012 14.3 0.0 0.021 13.5 0.0 1.4 1 1 0 1 1 1 0 Nickel-dependent hydrogenase NIF PF03031.13 CEH17310.1 - 1.1e-21 77.1 0.0 1.6e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 CEH17310.1 - 8.3e-05 21.9 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Adaptin_N PF01602.15 CEH17311.1 - 1.8e-51 175.0 2.3 2.3e-51 174.7 1.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF2435 PF10363.4 CEH17311.1 - 8.5e-06 25.5 0.9 8.2e-05 22.4 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 CEH17311.1 - 0.00023 21.0 0.7 0.00054 19.8 0.1 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CEH17311.1 - 0.00042 20.5 15.7 0.034 14.4 0.8 4.7 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 CEH17311.1 - 0.015 15.3 1.5 2 8.6 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat CinA PF02464.12 CEH17312.1 - 9.4e-33 112.8 0.1 1.1e-32 112.6 0.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein zf-RING_UBOX PF13445.1 CEH17313.1 - 1.5e-15 56.5 0.9 2.8e-15 55.7 0.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 CEH17313.1 - 3.2e-08 33.3 0.0 5.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-C3HC4 PF00097.20 CEH17313.1 - 0.00017 21.1 0.9 0.0003 20.4 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH17313.1 - 0.00027 20.6 0.8 0.00044 19.9 0.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CEH17313.1 - 0.00029 20.6 1.2 0.00058 19.6 0.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CEH17313.1 - 0.00088 18.8 0.9 0.0014 18.2 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH17313.1 - 0.0019 18.1 1.7 0.0032 17.4 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEH17313.1 - 0.0031 17.3 0.8 0.0054 16.5 0.5 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 CEH17313.1 - 0.018 14.2 0.1 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Alg14 PF08660.6 CEH17314.1 - 4.2e-47 160.3 0.0 9.1e-47 159.2 0.0 1.5 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Homeobox PF00046.24 CEH17316.1 - 3.6e-17 61.7 1.9 7.9e-17 60.6 1.3 1.6 1 0 0 1 1 1 1 Homeobox domain MRP-L20 PF12824.2 CEH17316.1 - 0.004 17.1 0.3 0.0081 16.1 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 BrkDBD PF09607.5 CEH17316.1 - 0.0046 16.4 0.4 0.022 14.3 0.7 1.9 2 0 0 2 2 2 1 Brinker DNA-binding domain HTH_23 PF13384.1 CEH17316.1 - 0.08 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HemS PF05171.7 CEH17316.1 - 0.13 12.1 0.0 0.42 10.4 0.0 1.9 1 1 0 1 1 1 0 Haemin-degrading HemS.ChuX domain DUF4471 PF14740.1 CEH17316.1 - 0.26 10.4 0.1 0.37 9.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Clr2 PF10383.4 CEH17317.1 - 6.6e-08 32.6 0.0 3.3e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 WW PF00397.21 CEH17317.1 - 1.5e-05 24.7 0.2 3.5e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 WW domain TIMELESS PF04821.9 CEH17318.1 - 1.3e-35 122.9 0.0 2.4e-34 118.7 0.0 2.4 1 1 0 1 1 1 1 Timeless protein DUF1295 PF06966.7 CEH17319.1 - 7e-35 120.4 0.0 1.4e-31 109.6 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1295) AMP-binding PF00501.23 CEH17320.1 - 2.4e-68 230.4 0.1 4.6e-68 229.5 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEH17320.1 - 4.8e-18 65.8 0.3 1e-17 64.8 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UvrD_C PF13361.1 CEH17323.1 - 1.5e-73 248.3 0.3 9.3e-45 153.6 0.4 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CEH17323.1 - 5.2e-60 203.3 0.4 1.3e-59 202.1 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 CEH17323.1 - 1.9e-12 46.7 0.4 1.6e-11 43.8 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 CEH17323.1 - 7.6e-10 38.8 0.0 2.1e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CEH17323.1 - 0.00072 19.1 0.0 0.063 12.7 0.0 2.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CEH17323.1 - 0.017 15.2 0.4 0.14 12.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain Arg_tRNA_synt_N PF03485.11 CEH17323.1 - 0.021 15.3 0.6 0.52 10.8 0.0 3.2 3 0 0 3 3 3 0 Arginyl tRNA synthetase N terminal domain Sec7 PF01369.15 CEH17324.1 - 5.7e-40 137.0 0.7 9.4e-40 136.3 0.5 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 CEH17324.1 - 5.2e-10 39.4 0.0 1.1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 CEH17324.1 - 2.2e-09 37.4 0.0 4.3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain TMP_2 PF06791.8 CEH17324.1 - 0.032 13.8 0.9 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein FAM53 PF15242.1 CEH17325.1 - 0.12 11.9 3.5 0.13 11.7 2.4 1.1 1 0 0 1 1 1 0 Family of FAM53 Myticin-prepro PF10690.4 CEH17325.1 - 1.9 8.5 5.7 1.4 8.9 3.1 1.4 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel adh_short PF00106.20 CEH17326.1 - 6.1e-65 218.2 7.1 1.4e-33 116.1 0.6 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CEH17326.1 - 3.7e-31 108.1 2.6 5.1e-16 58.8 0.2 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 CEH17326.1 - 4.9e-25 87.3 0.0 1.2e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 CEH17326.1 - 5.6e-19 68.8 4.5 6.8e-11 42.3 0.7 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 CEH17326.1 - 4.6e-07 29.6 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 CEH17326.1 - 1.6e-05 24.0 0.2 0.014 14.5 0.1 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 CEH17326.1 - 0.0096 15.6 1.6 1.4 8.7 0.0 2.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 CEH17326.1 - 0.091 12.4 12.3 0.26 10.9 0.5 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.7 CEH17326.1 - 2.4 8.1 9.8 3 7.8 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF543) DUF1365 PF07103.6 CEH17327.1 - 2.4e-28 98.8 0.0 6.2e-28 97.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) Pyridoxal_deC PF00282.14 CEH17328.1 - 1.4e-64 217.8 0.0 2.2e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CEH17328.1 - 0.00036 19.3 0.0 0.0006 18.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MutS_I PF01624.15 CEH17328.1 - 0.057 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 MutS domain I BLUF PF04940.7 CEH17329.1 - 4.6e-30 103.1 0.0 6.6e-30 102.6 0.0 1.2 1 0 0 1 1 1 1 Sensors of blue-light using FAD 2OG-FeII_Oxy PF03171.15 CEH17330.1 - 1e-08 35.3 0.0 2.6e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CEH17330.1 - 1.5e-07 31.9 0.0 2.9e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Redoxin PF08534.5 CEH17331.1 - 6.7e-30 103.5 0.1 8e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CEH17331.1 - 5.5e-12 45.4 0.0 8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family FAD_binding_4 PF01565.18 CEH17333.1 - 7.2e-19 67.6 0.3 1.4e-18 66.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Esterase PF00756.15 CEH17334.1 - 3.8e-44 151.0 0.0 4.6e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CEH17334.1 - 1.5e-06 28.0 0.1 2.2e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 CEH17334.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF3661 PF12400.3 CEH17335.1 - 7.3e-31 106.9 0.0 1e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein Virul_fac_BrkB PF03631.10 CEH17335.1 - 0.032 13.6 2.1 0.053 12.8 1.4 1.3 1 0 0 1 1 1 0 Virulence factor BrkB TUDOR PF00567.19 CEH17337.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 CEH17337.1 - 0.0073 15.4 9.8 0.0078 15.3 0.1 2.3 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) Vfa1 PF08432.5 CEH17337.1 - 1.4 8.9 8.0 6 6.8 0.1 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RP-C_C PF11800.3 CEH17337.1 - 3.2 7.4 10.7 0.25 10.9 2.3 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region Pro_CA PF00484.14 CEH17338.1 - 4.5e-27 94.9 0.0 5.6e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase MFS_1 PF07690.11 CEH17339.1 - 2.2e-20 72.7 23.2 7.8e-16 57.7 6.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CEH17339.1 - 0.034 13.9 2.2 0.094 12.5 0.1 2.8 4 0 0 4 4 4 0 MFS_1 like family TRAM_LAG1_CLN8 PF03798.11 CEH17340.1 - 1.3e-28 99.9 13.5 1.7e-28 99.5 9.4 1.1 1 0 0 1 1 1 1 TLC domain GST_N PF02798.15 CEH17341.1 - 1.4e-06 28.4 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CEH17341.1 - 2.7e-06 27.2 0.0 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEH17341.1 - 0.00026 21.4 0.1 0.00044 20.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CEH17341.1 - 0.00049 20.2 0.0 0.00094 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CEH17341.1 - 0.0037 17.1 0.1 0.011 15.6 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 CEH17342.1 - 3.4e-71 235.0 4.1 1.1e-23 82.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2723 PF11028.3 CEH17342.1 - 0.3 10.5 2.9 9.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) DUF3493 PF11998.3 CEH17343.1 - 0.029 14.2 7.6 0.04 13.8 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) Oxidored_FMN PF00724.15 CEH17344.1 - 1.1e-47 162.6 0.0 1.7e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family YadA_stalk PF05662.9 CEH17344.1 - 0.1 12.3 0.6 3.3 7.6 0.4 2.8 1 1 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin DPBB_1 PF03330.13 CEH17345.1 - 6.7e-10 38.8 0.3 1.1e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEH17345.1 - 8.7e-07 28.6 1.7 9.4e-07 28.5 0.6 1.5 1 1 1 2 2 2 1 Barwin family LTD PF00932.14 CEH17345.1 - 0.0029 17.6 0.1 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain HypA PF01155.14 CEH17345.1 - 0.023 14.3 0.1 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF1445 PF07286.7 CEH17345.1 - 0.089 12.4 0.0 0.096 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) zf-ribbon_3 PF13248.1 CEH17345.1 - 2.9 7.2 5.2 19 4.6 1.9 2.8 2 1 1 3 3 3 0 zinc-ribbon domain DNA_repr_REX1B PF14966.1 CEH17346.1 - 8.8e-07 29.2 1.3 0.019 15.3 0.0 2.9 3 0 0 3 3 3 2 DNA repair REX1-B RP-C_C PF11800.3 CEH17346.1 - 0.0039 16.9 6.2 0.18 11.5 0.1 2.2 2 0 0 2 2 2 2 Replication protein C C-terminal region Pex14_N PF04695.8 CEH17346.1 - 0.35 10.9 2.9 0.36 10.8 0.8 1.9 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WXG100 PF06013.7 CEH17346.1 - 2.1 8.3 5.7 52 3.9 0.8 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF3446 PF11928.3 CEH17346.1 - 6.3 7.0 11.2 3 8.0 4.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) GDC-P PF02347.11 CEH17347.1 - 1.2e-08 34.1 0.7 1.7e-07 30.3 0.1 2.0 2 0 0 2 2 2 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 CEH17347.1 - 0.00024 20.3 0.0 0.00037 19.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CEH17347.1 - 0.0034 16.1 0.1 0.0058 15.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 CEH17348.1 - 3e-120 401.7 0.0 3.8e-120 401.4 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein Ribosomal_S17e PF00833.13 CEH17351.1 - 3.6e-57 191.4 0.0 4.1e-57 191.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 CEH17351.1 - 0.034 14.8 0.1 0.16 12.7 0.0 1.9 1 1 1 2 2 2 0 Blue/Ultraviolet sensing protein C terminal Ribosomal_S8 PF00410.14 CEH17353.1 - 6.1e-26 90.7 0.1 8e-26 90.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 PE-PPE PF08237.6 CEH17354.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain TPMT PF05724.6 CEH17357.1 - 5.6e-34 117.4 0.0 6.6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.7 CEH17357.1 - 4.5e-08 33.4 0.0 8.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH17357.1 - 1.2e-07 31.5 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH17357.1 - 1.6e-07 31.8 0.0 2.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH17357.1 - 3e-07 30.4 0.0 6.1e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH17357.1 - 4.5e-07 29.5 0.0 6.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH17357.1 - 3.8e-06 27.2 0.0 8.5e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH17357.1 - 0.0022 18.3 0.0 0.0048 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Sfi1 PF08457.5 CEH17358.1 - 2.3e-15 56.0 54.8 2.3e-11 42.8 32.0 2.4 1 1 1 2 2 2 2 Sfi1 spindle body protein Sfi1 PF08457.5 CEH17359.1 - 1.5e-05 23.6 16.8 0.00065 18.2 2.5 2.0 1 1 0 1 1 1 1 Sfi1 spindle body protein Abhydrolase_5 PF12695.2 CEH17362.1 - 0.00042 20.0 0.1 0.00088 19.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CEH17362.1 - 0.00067 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 CEH17362.1 - 0.0009 18.8 0.1 0.0025 17.3 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold LCAT PF02450.10 CEH17362.1 - 0.0024 16.8 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CEH17362.1 - 0.0039 17.1 0.0 0.015 15.1 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family adh_short_C2 PF13561.1 CEH17363.1 - 6.1e-28 98.1 0.7 7.3e-28 97.9 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEH17363.1 - 1.7e-25 89.8 5.3 2.1e-25 89.5 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH17363.1 - 1.5e-12 47.5 3.0 2.3e-12 46.9 2.1 1.2 1 0 0 1 1 1 1 KR domain DUF711 PF05167.7 CEH17363.1 - 0.017 13.8 0.3 0.021 13.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) NAD_binding_10 PF13460.1 CEH17363.1 - 0.066 13.2 1.6 0.15 12.0 1.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 CEH17363.1 - 0.075 12.4 0.9 0.16 11.3 0.6 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AnfO_nitrog PF09582.5 CEH17363.1 - 0.09 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) IQ PF00612.22 CEH17364.1 - 0.00019 20.7 0.6 0.00046 19.5 0.4 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif SR-25 PF10500.4 CEH17364.1 - 0.0047 16.4 11.2 0.0047 16.4 7.7 2.6 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.2 CEH17364.1 - 0.087 12.3 9.6 3.2 7.1 0.1 2.8 2 0 0 2 2 2 0 SpoIIIAH-like protein FAM60A PF15396.1 CEH17364.1 - 7.7 6.2 14.3 1.1 8.9 0.9 2.5 2 0 0 2 2 2 0 Protein Family FAM60A Acetyltransf_1 PF00583.19 CEH17365.1 - 8.8e-09 35.2 0.0 1.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEH17365.1 - 4.2e-08 33.2 0.0 6.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 CEH17365.1 - 0.00047 20.6 0.0 0.001 19.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 CEH17365.1 - 0.0069 15.7 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 FR47 PF08445.5 CEH17365.1 - 0.011 15.4 0.1 0.042 13.5 0.1 1.8 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 CEH17365.1 - 0.094 12.8 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GFO_IDH_MocA PF01408.17 CEH17366.1 - 5.1e-26 91.5 0.6 5.1e-26 91.5 0.4 1.8 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 CEH17366.1 - 1.1e-05 25.7 0.6 2e-05 24.9 0.4 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CEH17366.1 - 0.0044 17.3 0.7 0.018 15.3 0.1 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Pex14_N PF04695.8 CEH17367.1 - 0.0029 17.6 1.9 0.0059 16.6 1.3 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_12 PF13424.1 CEH17367.1 - 0.0049 16.7 21.6 1.1 9.2 1.3 4.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 CEH17367.1 - 1.3 8.7 14.2 0.99 9.1 0.9 3.8 3 2 0 3 3 3 0 TPR repeat TPR_7 PF13176.1 CEH17367.1 - 2.4 8.1 8.2 5.8 6.9 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEH17367.1 - 9.7 5.9 9.7 60 3.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AhpC-TSA PF00578.16 CEH17368.1 - 4.1e-28 97.5 0.0 5.9e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CEH17368.1 - 2.7e-20 72.3 0.0 4.4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CEH17368.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF4551 PF15087.1 CEH17368.1 - 5.5 5.2 11.9 6.8 4.9 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CHCH PF06747.8 CEH17369.1 - 1.2e-05 25.0 1.3 1.6e-05 24.6 0.9 1.2 1 0 0 1 1 1 1 CHCH domain DB PF01682.14 CEH17369.1 - 0.0063 16.5 0.6 0.0066 16.4 0.4 1.1 1 0 0 1 1 1 1 DB module Abhydrolase_4 PF08386.5 CEH17372.1 - 2.3e-09 37.0 0.0 6.5e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 CEH17372.1 - 2.5e-08 33.7 0.2 0.0008 19.0 0.0 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEH17372.1 - 2.9e-08 33.8 3.5 3e-06 27.2 2.4 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH17372.1 - 0.0012 18.5 1.4 0.12 12.1 1.0 2.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1573 PF07610.6 CEH17373.1 - 0.0034 16.9 0.0 0.0048 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1573) Bap31 PF05529.7 CEH17374.1 - 4.8e-45 153.3 10.1 8.3e-43 146.0 0.6 2.1 2 0 0 2 2 2 2 B-cell receptor-associated protein 31-like DUF4407 PF14362.1 CEH17374.1 - 0.00021 20.3 0.6 0.00061 18.8 0.0 1.9 1 1 0 3 3 3 1 Domain of unknown function (DUF4407) DivIC PF04977.10 CEH17374.1 - 0.23 10.9 3.2 0.23 10.9 0.8 2.0 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 CEH17374.1 - 0.24 11.7 4.1 0.35 11.2 0.3 2.4 2 1 0 2 2 2 0 SlyX DUF4140 PF13600.1 CEH17374.1 - 0.32 11.4 2.9 0.63 10.5 2.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GrpE PF01025.14 CEH17374.1 - 1.7 8.1 5.5 0.44 10.0 1.9 1.4 2 0 0 2 2 2 0 GrpE Peptidase_U4 PF03419.8 CEH17374.1 - 5.4 6.0 10.0 7.2 5.5 6.9 1.4 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Metallophos PF00149.23 CEH17377.1 - 2.1e-07 30.5 0.4 2.1e-07 30.5 0.2 2.0 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.6 CEH17377.1 - 0.16 9.9 0.1 0.33 8.9 0.0 1.4 2 0 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase 4F5 PF04419.9 CEH17379.1 - 2.8e-05 24.7 9.3 3.9e-05 24.2 6.5 1.3 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.2 CEH17379.1 - 0.00025 20.9 2.9 0.00067 19.5 2.0 1.7 1 1 0 1 1 1 1 Zinc-binding zf-met PF12874.2 CEH17379.1 - 0.0085 16.2 0.4 0.071 13.3 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF466 PF04328.8 CEH17379.1 - 0.011 15.5 0.2 0.02 14.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF466) zf-Di19 PF05605.7 CEH17379.1 - 0.051 13.7 1.0 0.078 13.1 0.7 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CEH17379.1 - 0.098 13.0 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4591 PF15261.1 CEH17379.1 - 0.1 12.8 1.2 0.1 12.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) Npa1 PF11707.3 CEH17379.1 - 0.13 11.2 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal Cation_efflux PF01545.16 CEH17380.1 - 0.31 10.0 4.6 1.1 8.2 3.0 2.0 1 1 0 1 1 1 0 Cation efflux family DAO PF01266.19 CEH17381.1 - 3.4e-16 59.1 4.5 9.6e-16 57.6 3.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CEH17381.1 - 0.038 13.7 0.0 0.95 9.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding PMI_typeI PF01238.16 CEH17381.1 - 0.067 12.1 0.1 0.097 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I GST_N PF02798.15 CEH17382.1 - 3.7e-13 49.4 0.0 7.3e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEH17382.1 - 1.2e-10 41.2 0.0 2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CEH17382.1 - 1.4e-10 41.2 0.0 2.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CEH17382.1 - 4e-06 26.7 0.0 6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEH17382.1 - 1.5e-05 24.8 0.1 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEH17382.1 - 0.0014 19.1 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BolA PF01722.13 CEH17383.1 - 2.9e-15 55.9 0.0 4.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein MFS_1 PF07690.11 CEH17385.1 - 2.9e-34 118.3 24.3 2.9e-34 118.3 16.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Opy2 PF09463.5 CEH17386.1 - 0.067 13.2 18.9 0.11 12.5 13.1 1.4 1 0 0 1 1 1 0 Opy2 protein WD40 PF00400.27 CEH17387.1 - 9.1e-26 88.7 4.9 1.8e-10 40.2 0.7 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Pkinase PF00069.20 CEH17388.1 - 4.6e-65 219.3 0.0 6.7e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17388.1 - 3.6e-36 124.5 0.0 5.2e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH17388.1 - 0.00013 21.0 0.0 0.00045 19.2 0.0 1.7 1 1 1 2 2 2 1 Kinase-like DUF3422 PF11902.3 CEH17389.1 - 0.0035 16.2 6.0 0.0035 16.2 4.2 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3422) Baculo_PEP_C PF04513.7 CEH17389.1 - 0.1 12.4 1.6 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3461 PF11944.3 CEH17389.1 - 0.11 12.3 5.2 1.9 8.3 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3461) MtrG PF04210.8 CEH17389.1 - 0.24 11.0 0.8 0.6 9.8 0.1 2.1 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Osmo_CC PF08946.5 CEH17389.1 - 1.2 9.2 6.1 3.5 7.7 0.1 3.7 3 1 1 4 4 4 0 Osmosensory transporter coiled coil CoA_transf_3 PF02515.12 CEH17390.1 - 8.2e-37 126.2 0.7 5e-35 120.4 0.5 2.6 1 1 0 1 1 1 1 CoA-transferase family III Citrate_synt PF00285.16 CEH17391.1 - 1.1e-115 386.2 0.0 1.4e-115 385.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase CRAL_TRIO PF00650.15 CEH17392.1 - 2.6e-13 49.7 0.0 4.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain SLT PF01464.15 CEH17393.1 - 5.9e-13 48.3 0.1 1.3e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 Transglycosylase SLT domain DNA_pol_viral_N PF00242.12 CEH17393.1 - 0.26 10.2 4.8 0.39 9.6 3.3 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Sec3_C PF09763.4 CEH17393.1 - 0.75 7.8 3.0 1 7.3 2.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Macoilin PF09726.4 CEH17393.1 - 6.2 4.9 12.4 7.5 4.7 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein TPR_2 PF07719.12 CEH17394.1 - 0.00045 19.9 0.5 0.0015 18.2 0.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 CEH17394.1 - 0.001 18.5 0.3 0.0024 17.4 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.13 CEH17394.1 - 0.0018 18.1 0.2 0.0043 16.8 0.2 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 CEH17394.1 - 0.0047 16.5 0.1 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_7 PF13176.1 CEH17394.1 - 0.033 13.9 0.2 0.096 12.5 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 CEH17394.1 - 0.059 14.0 0.6 0.059 14.0 0.4 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat PFU PF09070.6 CEH17395.1 - 3.9e-43 146.1 0.0 1.1e-42 144.7 0.0 1.8 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 CEH17395.1 - 5e-37 124.4 9.0 1.8e-06 27.5 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.6 CEH17395.1 - 1.2e-35 122.6 0.0 1.6e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 CEH17395.1 - 0.00026 20.7 0.0 10 5.9 0.0 3.7 3 0 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region Arm PF00514.18 CEH17395.1 - 0.032 14.0 0.1 0.26 11.1 0.1 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat WD40 PF00400.27 CEH17396.1 - 1.8e-41 138.5 11.4 4.3e-06 26.3 0.1 10.7 10 1 0 10 10 10 7 WD domain, G-beta repeat Nbas_N PF15492.1 CEH17396.1 - 5.8e-06 25.6 0.0 0.28 10.2 0.0 3.7 4 0 0 4 4 4 3 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 CEH17396.1 - 0.0036 16.9 0.1 3.1 7.5 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 CEH17396.1 - 0.07 11.2 0.3 0.22 9.6 0.0 1.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 TruB_C PF09142.6 CEH17396.1 - 0.62 9.7 6.0 1.1 8.9 0.1 3.7 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal Sel1 PF08238.7 CEH17397.1 - 3.5e-14 52.8 18.1 3.4e-09 37.0 0.3 6.2 6 0 0 6 6 6 4 Sel1 repeat TPR_2 PF07719.12 CEH17397.1 - 0.019 14.8 0.3 0.52 10.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEH17397.1 - 0.49 10.9 5.1 71 4.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat SET PF00856.23 CEH17398.1 - 0.0035 17.6 0.0 0.026 14.8 0.0 2.1 1 1 0 1 1 1 1 SET domain PAS_9 PF13426.1 CEH17399.1 - 1.4e-26 92.9 0.0 3e-14 53.2 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 CEH17399.1 - 9.8e-16 57.5 0.0 8.8e-09 35.1 0.0 4.1 3 1 0 3 3 3 2 PAS fold PAS_3 PF08447.6 CEH17399.1 - 7e-14 51.6 0.0 2.1e-07 30.9 0.0 4.5 3 1 1 4 4 4 2 PAS fold PAS_4 PF08448.5 CEH17399.1 - 5.3e-08 32.8 0.3 6.9e-05 22.8 0.0 4.0 4 0 0 4 4 4 1 PAS fold PAS_8 PF13188.1 CEH17399.1 - 5.4e-05 22.8 0.0 0.13 12.1 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS_11 PF14598.1 CEH17399.1 - 9.1e-05 22.3 0.0 0.0015 18.5 0.0 2.8 2 1 1 3 3 3 1 PAS domain Enolase_C PF00113.17 CEH17400.1 - 9.1e-136 451.6 0.1 1.2e-135 451.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CEH17400.1 - 4.6e-54 181.8 0.2 7.9e-54 181.1 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CEH17400.1 - 0.0024 17.8 0.0 0.0059 16.5 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 CEH17400.1 - 0.015 15.7 0.0 0.045 14.2 0.0 1.9 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 CEH17400.1 - 0.083 11.8 0.4 0.17 10.7 0.1 1.6 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus YbaJ PF10757.4 CEH17401.1 - 0.0058 16.7 0.2 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Biofilm formation regulator YbaJ Glycoprotein_B PF00606.13 CEH17401.1 - 1.5 6.7 1.9 2.2 6.1 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Hydantoinase_B PF02538.9 CEH17403.1 - 6e-185 615.4 0.0 1.4e-184 614.2 0.0 1.5 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase DUF2347 PF09804.4 CEH17404.1 - 2.9e-22 79.2 0.0 5.7e-22 78.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 CEH17404.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Mito_carr PF00153.22 CEH17405.1 - 2.7e-35 119.9 1.0 1.1e-17 63.5 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein NYN PF01936.13 CEH17406.1 - 9.3e-23 81.1 0.0 1.8e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 NYN domain Tox-PLDMTX PF15645.1 CEH17406.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold V-SNARE_C PF12352.3 CEH17407.1 - 5.5e-16 58.3 0.4 1.1e-15 57.3 0.3 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CEH17407.1 - 8.3e-05 22.2 0.1 0.00023 20.7 0.0 1.7 2 0 0 2 2 2 1 Sec20 DUF726 PF05277.7 CEH17408.1 - 1.6e-113 379.0 0.5 2.1e-113 378.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Syndecan PF01034.15 CEH17408.1 - 0.19 11.4 0.4 0.52 9.9 0.3 1.7 1 0 0 1 1 1 0 Syndecan domain Methyltransf_11 PF08241.7 CEH17409.1 - 8.2e-11 42.2 0.0 1.5e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH17409.1 - 4.7e-10 39.8 0.0 1.7e-09 38.0 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH17409.1 - 3.2e-09 36.5 0.0 4.9e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH17409.1 - 4.3e-09 36.2 0.0 6.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH17409.1 - 0.00016 22.0 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEH17409.1 - 0.0004 19.5 0.0 0.00059 19.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CEH17409.1 - 0.0082 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Med3 PF11593.3 CEH17410.1 - 0.06 12.5 3.2 0.068 12.4 2.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRM_1 PF00076.17 CEH17411.1 - 2.6e-16 58.9 0.0 5.4e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH17411.1 - 3.7e-09 36.4 0.0 6.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH17411.1 - 4.3e-06 26.4 0.0 7.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEH17411.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Chorismate_bind PF00425.13 CEH17412.1 - 2.9e-67 226.7 0.0 8.1e-67 225.2 0.0 1.8 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 CEH17412.1 - 3.7e-23 81.9 0.0 4.8e-16 58.7 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 CEH17412.1 - 2.9e-11 43.5 0.0 3.4e-05 23.8 0.0 3.5 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 CEH17412.1 - 0.0026 17.2 0.1 0.24 10.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 ABC_tran PF00005.22 CEH17414.1 - 2.5e-32 112.0 0.4 4.3e-18 65.9 0.1 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CEH17414.1 - 6.5e-12 46.0 0.0 0.0067 16.4 0.0 3.3 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 CEH17414.1 - 2.9e-09 36.5 0.0 0.035 13.3 0.0 3.6 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 CEH17414.1 - 4.6e-09 35.8 0.1 9.4e-09 34.8 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HEAT_2 PF13646.1 CEH17414.1 - 6.3e-07 29.5 12.2 0.00079 19.6 0.7 4.7 1 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 CEH17414.1 - 4e-06 27.1 8.5 0.22 12.0 0.0 5.5 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 CEH17414.1 - 0.0002 21.1 0.7 12 6.2 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat AAA_15 PF13175.1 CEH17414.1 - 0.0002 20.5 0.0 0.053 12.5 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.1 CEH17414.1 - 0.00031 20.5 0.0 0.56 10.1 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit CLASP_N PF12348.3 CEH17414.1 - 0.0033 16.8 0.3 0.024 13.9 0.1 2.5 2 1 0 2 2 2 1 CLASP N terminal AAA_22 PF13401.1 CEH17414.1 - 0.021 14.9 0.1 0.48 10.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 CEH17414.1 - 0.028 13.9 0.5 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CEH17414.1 - 0.05 13.9 1.3 0.44 10.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain Adaptin_N PF01602.15 CEH17414.1 - 0.18 10.1 0.1 0.42 8.8 0.1 1.5 1 1 0 1 1 1 0 Adaptin N terminal region ABC_tran_2 PF12848.2 CEH17414.1 - 2.6 7.9 10.1 0.42 10.4 0.8 3.2 3 0 0 3 3 3 0 ABC transporter zf-UBR PF02207.15 CEH17415.1 - 8.7e-11 41.3 8.1 8.7e-11 41.3 5.6 3.5 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 CEH17415.1 - 0.00011 21.8 1.1 0.00011 21.8 0.8 3.7 3 1 1 4 4 4 1 PHD-finger K167R PF08065.7 CEH17423.1 - 0.0033 17.5 0.8 0.0043 17.1 0.6 1.1 1 0 0 1 1 1 1 K167R (NUC007) repeat DUF1019 PF06254.6 CEH17423.1 - 0.068 13.3 0.4 0.095 12.8 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1019) STN1_2 PF09170.5 CEH17423.1 - 0.1 12.3 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 HMD PF03201.11 CEH17423.1 - 0.11 12.4 0.3 0.33 10.8 0.0 1.8 2 1 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF3808 PF10300.4 CEH17424.1 - 0.16 10.5 2.7 0.26 9.7 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3808) SSFA2_C PF14723.1 CEH17425.1 - 0.0064 16.2 7.4 0.014 15.1 5.1 1.6 1 0 0 1 1 1 1 Sperm-specific antigen 2 C-terminus Vps5 PF09325.5 CEH17425.1 - 0.031 13.5 17.0 0.05 12.8 11.6 1.4 1 1 0 1 1 1 0 Vps5 C terminal like tRNA-synt_1g PF09334.6 CEH17425.1 - 0.073 11.7 2.0 0.095 11.3 1.4 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) DUF4375 PF14300.1 CEH17425.1 - 0.35 10.8 4.2 0.64 10.0 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) DUF3552 PF12072.3 CEH17425.1 - 0.66 9.1 28.6 1.5 7.9 10.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF2052 PF09747.4 CEH17425.1 - 2.5 7.9 10.9 4.2 7.2 7.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Apolipoprotein PF01442.13 CEH17426.1 - 2 7.8 53.6 95 2.3 37.2 2.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Ycf1 PF05758.7 CEH17426.1 - 3.3 5.2 8.2 3.9 5.0 5.7 1.1 1 0 0 1 1 1 0 Ycf1 LtrA PF06772.6 CEH17429.1 - 3.1e-22 78.9 19.8 3.7e-11 42.5 0.2 2.7 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) KbaA PF14089.1 CEH17429.1 - 0.0022 17.5 4.5 0.0022 17.5 3.1 1.9 2 0 0 2 2 2 1 KinB-signalling pathway activation in sporulation Cpn60_TCP1 PF00118.19 CEH17431.1 - 3.6e-120 401.8 2.7 5.1e-120 401.3 1.8 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M22 PF00814.20 CEH17432.1 - 4.1e-80 269.1 0.0 3.7e-67 226.6 0.0 2.7 1 1 1 2 2 2 2 Glycoprotease family Amidase PF01425.16 CEH17432.1 - 3e-63 214.2 0.0 4.1e-58 197.2 0.0 2.5 2 1 0 2 2 2 2 Amidase ELH PF02323.10 CEH17432.1 - 0.025 13.7 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Egg-laying hormone precursor Spermine_synth PF01564.12 CEH17432.1 - 0.086 11.7 0.2 11 4.8 0.0 2.3 2 0 0 2 2 2 0 Spermine/spermidine synthase NUFIP1 PF10453.4 CEH17433.1 - 3.9e-12 45.4 1.7 1.1e-11 44.0 1.2 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 CEH17433.1 - 2.9e-05 23.6 0.8 5.1e-05 22.8 0.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 CEH17437.1 - 2.8e-05 23.8 3.4 2.8e-05 23.8 2.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CEH17437.1 - 0.00027 20.9 5.0 0.00074 19.5 3.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CEH17437.1 - 0.00029 20.4 4.1 0.0011 18.5 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH17437.1 - 0.00044 20.2 2.0 0.00044 20.2 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH17437.1 - 0.0013 18.3 2.1 0.0013 18.3 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH17437.1 - 0.0046 16.6 7.5 0.024 14.3 5.2 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 CEH17437.1 - 0.061 12.9 1.3 0.096 12.2 0.2 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 CEH17437.1 - 0.18 11.7 3.2 0.41 10.6 2.2 1.6 1 0 0 1 1 1 0 RING-like domain zf-Apc11 PF12861.2 CEH17437.1 - 0.46 10.3 3.3 1.2 8.9 0.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Asp-B-Hydro_N PF05279.6 CEH17437.1 - 6 6.6 9.7 0.45 10.3 3.4 1.5 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DUF3365 PF11845.3 CEH17437.1 - 9.6 6.0 10.4 1.7 8.4 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3365) tRNA_int_endo PF01974.12 CEH17438.1 - 1e-18 66.8 0.0 2.4e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 CEH17438.1 - 0.0061 16.0 0.1 0.58 9.7 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain LTV PF04180.9 CEH17438.1 - 1.4 8.3 7.4 0.37 10.2 2.6 1.6 1 1 1 2 2 2 0 Low temperature viability protein Cys_Met_Meta_PP PF01053.15 CEH17439.1 - 1.1e-55 188.5 0.0 8.1e-46 156.0 0.0 2.5 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Avl9 PF09794.4 CEH17440.1 - 1.3e-131 438.6 0.0 1.7e-131 438.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 CEH17440.1 - 8.8e-09 35.0 0.0 6.5e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 CEH17440.1 - 5.1e-07 29.2 0.0 2.5e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 CEH17440.1 - 0.0012 18.8 0.0 0.0053 16.7 0.0 2.1 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.16 CEH17440.1 - 0.049 13.3 0.0 2.9 7.5 0.0 2.8 3 0 0 3 3 3 0 DENN (AEX-3) domain Hydrolase_like2 PF13246.1 CEH17441.1 - 5.6e-21 74.3 0.1 8.7e-10 38.4 0.0 2.7 2 1 1 3 3 3 2 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEH17441.1 - 2.5e-15 57.1 0.1 1.2e-14 54.8 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CEH17441.1 - 1.9e-14 53.2 0.0 1.9e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CEH17441.1 - 4.7e-10 40.2 0.3 7.5e-07 29.7 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEH17441.1 - 0.00027 20.6 0.1 0.0046 16.5 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEH17441.1 - 0.045 13.9 0.1 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3729 PF12526.3 CEH17442.1 - 0.096 14.0 0.2 0.1 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) Gly-rich_Ago1 PF12764.2 CEH17445.1 - 0.81 10.3 3.7 0.37 11.4 0.4 1.9 1 1 1 2 2 2 0 Glycine-rich region of argonaut Chromo PF00385.19 CEH17447.1 - 2.3e-14 52.7 0.3 2.3e-14 52.7 0.2 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CEH17447.1 - 1.4e-09 37.6 0.1 8.8e-06 25.4 0.0 2.6 2 0 0 2 2 2 2 Chromo shadow domain DDHD PF02862.12 CEH17447.1 - 0.0039 17.0 19.8 0.0048 16.7 4.1 2.1 2 0 0 2 2 2 2 DDHD domain Merozoite_SPAM PF07133.6 CEH17447.1 - 0.027 14.3 32.0 0.11 12.4 3.1 2.2 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Tim54 PF11711.3 CEH17447.1 - 0.1 11.2 13.3 0.08 11.5 0.3 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Cwf_Cwc_15 PF04889.7 CEH17447.1 - 0.12 12.0 37.2 0.041 13.5 14.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Spore_coat_CotO PF14153.1 CEH17447.1 - 0.4 10.1 25.0 0.89 8.9 3.4 2.1 2 0 0 2 2 2 0 Spore coat protein CotO CDC45 PF02724.9 CEH17447.1 - 4.2 5.2 27.3 1.2 7.0 3.0 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF1510 PF07423.6 CEH17447.1 - 9.4 5.5 38.0 2.6 7.3 7.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) HA2 PF04408.18 CEH17449.1 - 8.2e-18 64.3 0.1 2.8e-17 62.5 0.1 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 CEH17449.1 - 6.4e-12 45.2 0.0 1.8e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH17449.1 - 2.2e-11 43.4 0.1 5.8e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CEH17449.1 - 6.4e-09 35.6 0.0 2.2e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CEH17449.1 - 0.00038 20.6 0.1 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CEH17449.1 - 0.0017 17.2 0.0 0.0041 16.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 CEH17449.1 - 0.044 13.5 1.9 0.26 11.0 0.1 3.3 3 0 0 3 3 3 0 Part of AAA domain KaiC PF06745.8 CEH17449.1 - 0.077 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 CEH17449.1 - 0.2 10.5 0.0 2.3 6.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain tRNA_int_end_N2 PF12928.2 CEH17450.1 - 8e-13 47.6 0.3 1.6e-05 24.2 0.1 2.4 2 0 0 2 2 2 2 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 CEH17450.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain TPR_11 PF13414.1 CEH17451.1 - 1.1e-14 53.7 4.7 2e-11 43.3 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CEH17451.1 - 1.7e-08 33.7 2.2 0.028 14.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEH17451.1 - 6.3e-07 28.7 0.9 0.13 11.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEH17451.1 - 9.8e-05 22.9 2.2 0.28 11.9 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEH17451.1 - 0.00027 21.1 2.1 0.056 13.7 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CEH17451.1 - 0.0092 16.5 0.6 6.5 7.6 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEH17451.1 - 0.07 12.9 0.8 9.7 6.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_B PF00136.16 CEH17452.1 - 2.1e-110 369.7 0.0 2.7e-110 369.3 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 CEH17452.1 - 3.3e-53 179.8 4.4 6.8e-53 178.8 3.0 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 CEH17452.1 - 2.4e-22 79.2 0.0 4.2e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 CEH17452.1 - 3.3e-17 62.0 4.0 3.3e-17 62.0 2.8 2.5 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal Nop14 PF04147.7 CEH17452.1 - 0.41 8.4 5.4 0.65 7.8 3.7 1.2 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 CEH17452.1 - 0.83 9.2 5.3 1.9 8.0 3.6 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Tannase PF07519.6 CEH17453.1 - 3.8e-62 210.5 1.7 3.6e-47 161.1 0.0 4.0 3 1 0 3 3 3 3 Tannase and feruloyl esterase Esterase PF00756.15 CEH17453.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PDDEXK_1 PF12705.2 CEH17454.1 - 0.0019 17.6 0.1 0.0024 17.2 0.1 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily zf-CCCH PF00642.19 CEH17456.1 - 2.5e-09 36.6 2.5 4e-09 35.9 1.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ORC4_C PF14629.1 CEH17457.1 - 2.1e-33 115.4 0.1 4.4e-33 114.3 0.1 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 CEH17457.1 - 5.5e-16 59.0 8.2 9.1e-15 55.1 0.2 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 CEH17457.1 - 0.0032 17.6 0.4 0.24 11.5 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 CEH17457.1 - 0.038 13.9 0.0 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CEH17457.1 - 0.04 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 CEH17457.1 - 0.047 13.4 0.1 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 CEH17457.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 CEH17457.1 - 0.087 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 CEH17457.1 - 0.1 12.7 0.1 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CEH17457.1 - 0.11 12.7 0.1 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 ABC transporter Glyco_hydro_47 PF01532.15 CEH17459.1 - 1.5e-101 340.3 0.2 1.7e-101 340.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CBFD_NFYB_HMF PF00808.18 CEH17460.1 - 1.8e-16 59.9 1.9 3.1e-16 59.1 0.2 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEH17460.1 - 0.052 13.6 0.1 0.052 13.6 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 YolD PF08863.5 CEH17460.1 - 0.12 12.2 0.4 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 YolD-like protein Bromo_TP PF07524.8 CEH17460.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 Bromodomain associated Aminotran_4 PF01063.14 CEH17461.1 - 2.3e-16 59.9 0.0 3.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Steroid_dh PF02544.11 CEH17462.1 - 1.2e-16 60.8 0.0 2.1e-07 30.8 0.0 3.4 3 0 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase eRF1_1 PF03463.10 CEH17463.1 - 8e-48 161.3 0.0 1.3e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 CEH17463.1 - 2.4e-22 79.7 0.0 3.6e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CEH17463.1 - 1.3e-21 76.9 0.0 2.7e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 Transposase_22 PF02994.9 CEH17464.1 - 0.03 12.8 4.0 0.6 8.5 0.0 2.2 2 0 0 2 2 2 0 L1 transposable element APG6 PF04111.7 CEH17464.1 - 2.1 7.3 15.4 4.7 6.1 0.6 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF607 PF04678.8 CEH17464.1 - 2.5 7.9 8.9 0.25 11.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Myosin_head PF00063.16 CEH17465.1 - 3.1e-217 722.8 0.0 5.4e-217 722.1 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CEH17465.1 - 4.1e-41 140.4 0.0 6e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 CEH17465.1 - 9.7e-11 40.8 0.6 1.9e-10 39.9 0.4 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEH17465.1 - 1.1e-10 40.9 0.2 2.6e-10 39.7 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEH17465.1 - 5.3e-07 29.0 0.0 1.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CEH17465.1 - 0.00011 22.3 0.6 0.00031 20.8 0.4 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 CEH17465.1 - 0.0022 18.1 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEH17465.1 - 0.0095 16.7 0.1 0.069 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CEH17465.1 - 0.01 15.5 0.0 0.03 14.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Hpr_kinase_C PF07475.7 CEH17465.1 - 0.012 14.9 0.1 0.29 10.4 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 CEH17465.1 - 0.022 13.8 0.0 0.054 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin SH3_4 PF06347.8 CEH17465.1 - 0.046 13.2 0.4 0.12 11.9 0.3 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Sigma54_activat PF00158.21 CEH17465.1 - 0.048 13.1 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 CEH17465.1 - 0.056 13.4 0.0 0.23 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CEH17465.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 CEH17465.1 - 0.082 13.2 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 CEH17465.1 - 0.083 11.4 0.4 0.23 10.0 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.10 CEH17465.1 - 0.17 11.5 0.0 0.47 10.1 0.0 1.8 1 0 0 1 1 1 0 NTPase Hexapep PF00132.19 CEH17466.1 - 1.1e-05 24.6 4.5 0.064 12.7 0.2 3.5 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CEH17466.1 - 1.1 8.8 10.7 6.8 6.3 2.6 4.1 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase TIM PF00121.13 CEH17467.1 - 1.4e-90 302.6 0.1 1.6e-90 302.4 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 CEH17467.1 - 0.0021 17.3 0.1 0.0071 15.6 0.1 1.8 1 1 1 2 2 2 1 CutC family zf-C2H2 PF00096.21 CEH17468.1 - 4.8e-21 73.7 30.1 1.6e-05 24.9 0.8 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CEH17468.1 - 2.5e-20 71.7 27.5 1.1e-09 38.0 0.1 6.2 5 1 1 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEH17468.1 - 2.3e-08 33.8 25.8 0.017 15.4 0.4 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger XPA_N PF01286.13 CEH17468.1 - 0.062 12.9 1.7 0.12 12.0 0.3 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_jaz PF12171.3 CEH17468.1 - 0.092 12.9 10.9 3.7 7.7 0.2 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CEH17468.1 - 0.26 11.2 14.4 0.17 11.8 0.3 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger Pro_CA PF00484.14 CEH17469.1 - 4.8e-23 81.8 0.0 6.9e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase RRM_6 PF14259.1 CEH17471.1 - 1.5e-09 37.6 0.0 2.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEH17471.1 - 5.5e-09 35.5 0.0 8e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH17471.1 - 2.6e-06 27.1 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPN7 PF10602.4 CEH17473.1 - 5.6e-45 152.8 0.0 1.3e-44 151.6 0.0 1.6 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CEH17473.1 - 7.9e-07 29.3 0.0 2.4e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 PCI domain ST7 PF04184.7 CEH17473.1 - 0.01 14.1 0.0 0.014 13.6 0.0 1.2 1 0 0 1 1 1 0 ST7 protein TPR_2 PF07719.12 CEH17473.1 - 0.018 14.9 0.2 2.2 8.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEH17473.1 - 0.055 13.0 0.3 1.1 8.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEH17473.1 - 0.069 13.0 2.1 0.34 10.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Med3 PF11593.3 CEH17473.1 - 0.31 10.2 1.2 0.42 9.8 0.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WD40 PF00400.27 CEH17474.1 - 6.4e-47 155.8 21.2 3.8e-09 36.0 0.2 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 CEH17474.1 - 3.7e-09 36.1 0.0 8.3e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CEH17474.1 - 2.4e-05 22.7 7.8 0.37 8.8 0.2 5.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CEH17474.1 - 0.0063 16.7 2.2 1.5 9.1 0.0 4.3 3 1 0 3 3 3 1 PQQ-like domain F-box PF00646.28 CEH17474.1 - 0.021 14.4 0.1 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box domain FimP PF09766.4 CEH17475.1 - 2.1e-28 99.4 9.8 3e-28 98.9 6.8 1.2 1 0 0 1 1 1 1 Fms-interacting protein DivIC PF04977.10 CEH17475.1 - 0.32 10.5 4.3 1.6 8.2 0.2 2.7 2 1 0 2 2 2 0 Septum formation initiator DUF641 PF04859.7 CEH17475.1 - 1.7 8.4 8.1 0.86 9.3 0.5 2.5 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) BRCA-2_OB1 PF09103.5 CEH17476.1 - 9e-27 93.1 0.0 1.5e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 CEH17476.1 - 5e-09 36.0 0.5 9.7e-09 35.0 0.3 1.4 1 0 0 1 1 1 1 BRCA2, helical SNase PF00565.12 CEH17477.1 - 2.6e-49 166.0 1.0 1.6e-19 70.1 0.0 6.5 6 1 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 CEH17477.1 - 2.8e-16 59.4 0.0 7.9e-16 58.0 0.0 1.7 2 0 0 2 2 2 1 Tudor domain Kin17_mid PF10357.4 CEH17478.1 - 8.5e-46 154.7 1.3 8.5e-46 154.7 0.9 1.7 2 1 0 2 2 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 CEH17478.1 - 5.7e-07 29.4 2.6 1.5e-06 28.1 1.8 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEH17478.1 - 0.0017 18.5 2.5 0.004 17.3 1.7 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CEH17478.1 - 0.003 17.6 0.9 0.028 14.5 0.0 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Cdc6_C PF09079.6 CEH17478.1 - 0.01 15.5 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal K_oxygenase PF13434.1 CEH17478.1 - 0.017 14.0 0.1 0.025 13.5 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) AKAP95 PF04988.7 CEH17478.1 - 0.023 14.4 0.5 0.045 13.5 0.3 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 CEH17478.1 - 0.036 14.3 1.1 0.093 13.1 0.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF629 PF04780.7 CEH17478.1 - 0.043 12.3 0.3 0.087 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Spore_III_AB PF09548.5 CEH17478.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) zf-C2H2 PF00096.21 CEH17478.1 - 1 9.8 3.9 0.46 10.9 0.9 1.9 2 0 0 2 2 1 0 Zinc finger, C2H2 type zf-DBF PF07535.7 CEH17478.1 - 3.6 7.3 6.4 4.4 7.0 0.8 2.5 2 0 0 2 2 2 0 DBF zinc finger DUF3449 PF11931.3 CEH17478.1 - 7.6 5.9 8.3 2.1 7.8 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) HA2 PF04408.18 CEH17479.1 - 2.5e-22 78.8 0.0 7.2e-22 77.3 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CEH17479.1 - 1.2e-21 76.5 0.0 3.1e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CEH17479.1 - 1.2e-13 50.7 0.0 2.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEH17479.1 - 2.9e-07 30.1 0.0 7.4e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEH17479.1 - 0.00015 21.9 0.0 0.00055 20.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CEH17479.1 - 0.0036 16.2 0.2 0.0081 15.0 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 CEH17479.1 - 0.018 14.9 0.1 0.52 10.2 0.1 2.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CEH17479.1 - 0.049 12.7 0.0 0.25 10.3 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin PhoH PF02562.11 CEH17479.1 - 0.12 11.5 0.0 0.76 8.9 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.1 CEH17479.1 - 0.23 11.7 0.0 0.47 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Alk_phosphatase PF00245.15 CEH17480.1 - 4.7e-90 302.2 0.1 5.6e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Alpha-amylase PF00128.19 CEH17482.1 - 1.6e-92 310.3 0.1 2e-92 310.0 0.1 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 CEH17482.1 - 0.0087 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Pkinase PF00069.20 CEH17483.1 - 4.9e-50 170.0 0.0 4.7e-49 166.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17483.1 - 2.4e-27 95.6 0.0 1.2e-26 93.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH17483.1 - 0.019 13.9 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 CEH17483.1 - 0.043 12.8 0.2 0.082 11.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_4 PF15404.1 CEH17484.1 - 1.7e-40 138.5 0.0 4.5e-40 137.1 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CEH17484.1 - 0.028 14.6 0.0 53 4.0 0.0 3.8 3 2 0 3 3 3 0 PH domain PH_9 PF15410.1 CEH17484.1 - 0.26 11.4 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain SKG6 PF08693.5 CEH17486.1 - 0.011 15.0 0.2 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Eno-Rase_NADH_b PF12242.3 CEH17486.1 - 0.05 13.4 0.5 0.12 12.1 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FGGY_N PF00370.16 CEH17487.1 - 0.013 14.8 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Pheromone PF08015.6 CEH17488.1 - 4.3 8.2 10.7 20 6.1 7.0 2.5 1 1 0 1 1 1 0 Fungal mating-type pheromone NADH-u_ox-rdase PF10785.4 CEH17489.1 - 3.7e-32 110.4 0.3 4.8e-32 110.0 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 CEH17489.1 - 2e-12 46.6 0.0 3.1e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Aminotran_1_2 PF00155.16 CEH17490.1 - 4.3e-40 137.7 0.0 7.8e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CEH17490.1 - 0.046 12.0 0.0 0.081 11.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme TraI_2 PF07514.6 CEH17490.1 - 0.063 12.0 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative helicase ATG11 PF10377.4 CEH17491.1 - 3.7e-31 107.6 0.0 1.1e-30 106.1 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein 11 Spc7 PF08317.6 CEH17491.1 - 5.8 5.4 26.0 4.3 5.9 5.2 4.0 2 1 2 4 4 4 0 Spc7 kinetochore protein Epimerase PF01370.16 CEH17492.1 - 0.00085 18.8 0.0 0.037 13.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family FMO-like PF00743.14 CEH17494.1 - 9.5e-27 93.3 0.0 5.2e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CEH17494.1 - 6.7e-20 72.0 0.0 1.4e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEH17494.1 - 2.2e-12 47.3 0.0 6.8e-11 42.4 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH17494.1 - 1.2e-08 34.8 0.0 2.8e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CEH17494.1 - 2.8e-06 26.5 0.2 8.7e-06 24.8 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 CEH17494.1 - 8.5e-06 24.9 0.9 0.0001 21.3 0.1 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 CEH17494.1 - 9.1e-06 25.5 0.1 3.5e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 CEH17494.1 - 1.8e-05 25.0 0.3 0.00025 21.4 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CEH17494.1 - 1.8e-05 23.9 0.1 0.00016 20.8 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 CEH17494.1 - 0.00053 19.4 0.4 0.0014 18.0 0.3 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 CEH17494.1 - 0.0024 16.9 0.0 0.0048 15.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CEH17494.1 - 0.0028 16.8 0.1 0.0062 15.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 CEH17494.1 - 0.025 13.4 0.2 0.12 11.2 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain IlvN PF07991.7 CEH17494.1 - 0.029 13.7 0.1 5.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 CEH17494.1 - 0.032 13.3 0.1 4.9 6.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CEH17494.1 - 0.033 14.4 0.0 9.8 6.4 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 CEH17494.1 - 0.12 11.9 0.2 1.2 8.7 0.1 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CEH17494.1 - 0.15 11.6 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 CEH17494.1 - 0.23 9.8 0.2 0.41 9.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein AT_hook PF02178.14 CEH17495.1 - 0.13 11.9 15.1 0.57 10.0 2.9 3.3 2 0 0 2 2 2 0 AT hook motif RRM_1 PF00076.17 CEH17497.1 - 0.00072 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH17497.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH17497.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CHC2 PF01807.15 CEH17498.1 - 0.11 12.0 0.1 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 CHC2 zinc finger Mpt_N PF09176.6 CEH17498.1 - 0.12 12.3 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Gar1 PF04410.9 CEH17499.1 - 2.3e-29 101.8 0.3 5e-28 97.5 0.1 2.7 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region BTB_2 PF02214.17 CEH17499.1 - 0.00063 19.8 0.0 0.004 17.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain TRAM_LAG1_CLN8 PF03798.11 CEH17500.1 - 2.9e-30 105.2 28.8 2.9e-30 105.2 20.0 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CEH17500.1 - 4.5e-15 54.8 0.0 1.1e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein Abhydrolase_6 PF12697.2 CEH17502.1 - 4.8e-27 95.3 0.0 7.6e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH17502.1 - 1.4e-11 44.4 0.0 8.6e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH17502.1 - 7.1e-08 32.3 0.0 2.5e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CEH17502.1 - 0.0027 17.5 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 CEH17502.1 - 0.013 14.6 0.0 0.17 11.0 0.0 2.4 2 1 1 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CEH17502.1 - 0.085 12.2 0.0 22 4.4 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Cu_amine_oxid PF01179.15 CEH17503.1 - 1.1e-155 518.4 0.0 2.3e-125 418.5 0.0 2.0 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 CEH17503.1 - 2.9e-14 52.9 0.0 5.4e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Mannosyl_trans PF05007.8 CEH17504.1 - 2.6e-52 178.0 9.0 2.6e-52 178.0 6.3 2.3 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 CEH17504.1 - 3.7e-09 35.9 6.9 6.4e-07 28.5 0.1 3.3 2 1 1 3 3 3 2 GPI transamidase subunit PIG-U DUF2029 PF09594.5 CEH17504.1 - 0.00041 19.9 18.0 0.00041 19.9 12.5 4.3 3 1 1 4 4 4 3 Protein of unknown function (DUF2029) Pro_dh PF01619.13 CEH17505.1 - 5.4e-40 137.2 0.0 5.7e-19 68.2 0.0 3.2 2 1 1 3 3 3 3 Proline dehydrogenase FGGY_C PF02782.11 CEH17506.1 - 1.3e-42 145.6 0.1 1.3e-42 145.6 0.1 2.1 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CEH17506.1 - 7.8e-19 67.9 0.7 1.4e-09 37.6 0.0 3.1 3 0 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 CEH17506.1 - 0.0004 19.7 0.1 0.012 14.9 0.0 2.3 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Phage_GPL PF05926.6 CEH17506.1 - 0.56 10.0 3.0 10 5.9 0.2 3.2 3 0 0 3 3 3 0 Phage head completion protein (GPL) Methyltransf_33 PF10017.4 CEH17507.1 - 5.3e-34 116.8 0.2 8.5e-34 116.1 0.1 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 CEH17507.1 - 2.1e-10 40.4 0.0 7.8e-09 35.2 0.0 2.3 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 CEH17507.1 - 0.0022 18.3 0.1 0.018 15.3 0.0 2.5 1 1 1 2 2 2 2 DinB superfamily GFA PF04828.9 CEH17508.1 - 0.031 14.1 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme NinF PF05810.7 CEH17508.1 - 0.1 12.4 0.2 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 NinF protein zf-CCHC PF00098.18 CEH17510.1 - 3e-09 36.3 12.6 1.4e-05 24.7 1.2 2.5 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 CEH17510.1 - 1.4e-05 24.5 1.0 2.9e-05 23.6 0.7 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 CEH17510.1 - 3e-05 23.6 11.0 0.0028 17.3 2.4 2.3 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 CEH17510.1 - 0.00013 21.5 0.1 0.00033 20.2 0.1 1.7 1 0 0 1 1 1 1 KH domain PolC_DP2 PF03833.8 CEH17510.1 - 0.54 7.8 3.1 0.79 7.3 2.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CCHC_4 PF14392.1 CEH17510.1 - 2.4 7.9 10.1 4.5 7.0 2.0 2.5 2 0 0 2 2 2 0 Zinc knuckle WD40 PF00400.27 CEH17511.1 - 8.8e-16 57.1 17.7 1.1e-08 34.6 0.5 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Rax2 PF12768.2 CEH17511.1 - 0.0004 19.6 0.0 0.054 12.7 0.0 2.2 2 0 0 2 2 2 2 Cortical protein marker for cell polarity DPPIV_N PF00930.16 CEH17511.1 - 0.0062 15.1 0.6 1.7 7.1 0.1 2.8 2 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region CsbD PF05532.7 CEH17512.1 - 5.7e-16 57.9 18.7 2.6e-10 39.7 4.9 2.0 1 1 1 2 2 2 2 CsbD-like DUF4611 PF15387.1 CEH17512.1 - 0.13 12.4 1.3 0.54 10.4 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Gp5_C PF06715.7 CEH17512.1 - 0.15 11.9 4.8 3.6 7.6 0.1 3.2 3 1 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) Pkinase PF00069.20 CEH17513.1 - 7.5e-25 87.5 0.0 6.6e-11 41.8 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17513.1 - 2.2e-08 33.4 0.0 0.00052 19.1 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Fungal_trans PF04082.13 CEH17514.1 - 1.2e-11 44.0 0.1 2.2e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH17514.1 - 1.6e-05 24.7 8.3 3.3e-05 23.7 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 CEH17514.1 - 2.5 8.3 9.1 4.7 7.4 6.3 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region ADH_zinc_N PF00107.21 CEH17516.1 - 2.1e-13 49.9 0.2 4.9e-13 48.7 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH17516.1 - 2.8e-09 36.6 0.0 5.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 CEH17516.1 - 0.0012 18.8 0.5 0.0025 17.8 0.2 1.6 2 0 0 2 2 2 1 NADH(P)-binding AAA PF00004.24 CEH17517.1 - 5.3e-39 133.4 0.0 8.3e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CEH17517.1 - 2.8e-06 26.5 0.1 6.1e-06 25.4 0.0 1.5 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CEH17517.1 - 8.6e-06 25.9 0.1 0.00025 21.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEH17517.1 - 2.2e-05 25.2 0.0 4.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CEH17517.1 - 2.7e-05 23.9 0.1 0.0001 22.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CEH17517.1 - 3.5e-05 23.7 0.0 7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CEH17517.1 - 4.4e-05 22.7 0.3 0.002 17.3 0.2 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CEH17517.1 - 7e-05 22.8 0.1 0.0063 16.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CEH17517.1 - 7.9e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CEH17517.1 - 0.00015 21.6 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CEH17517.1 - 0.00019 21.4 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CEH17517.1 - 0.0002 20.8 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CEH17517.1 - 0.00029 21.1 0.0 0.0016 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CEH17517.1 - 0.0005 18.9 0.2 0.0033 16.2 0.1 2.1 2 1 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 CEH17517.1 - 0.0014 18.0 1.2 0.027 13.8 0.3 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 CEH17517.1 - 0.0019 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEH17517.1 - 0.0041 16.2 0.4 0.0079 15.3 0.2 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 CEH17517.1 - 0.0079 15.6 0.1 0.043 13.2 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 CEH17517.1 - 0.008 16.3 0.0 0.021 14.9 0.0 1.7 1 1 1 2 2 1 1 RNA helicase AAA_24 PF13479.1 CEH17517.1 - 0.0092 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH17517.1 - 0.0095 15.6 0.6 0.026 14.2 0.4 1.7 1 0 0 1 1 1 1 Part of AAA domain Guanylate_kin PF00625.16 CEH17517.1 - 0.014 14.8 0.0 0.036 13.5 0.0 1.7 2 0 0 2 2 1 0 Guanylate kinase NACHT PF05729.7 CEH17517.1 - 0.015 14.9 0.3 0.093 12.3 0.1 2.3 3 0 0 3 3 3 0 NACHT domain DUF815 PF05673.8 CEH17517.1 - 0.027 13.3 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 CEH17517.1 - 0.028 13.6 0.0 0.057 12.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 CEH17517.1 - 0.033 13.0 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IPT PF01745.11 CEH17517.1 - 0.05 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase CPT PF07931.7 CEH17517.1 - 0.067 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.6 CEH17517.1 - 0.081 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CEH17517.1 - 0.085 13.1 0.2 0.2 11.9 0.0 1.7 2 0 0 2 2 1 0 ABC transporter UPF0079 PF02367.12 CEH17517.1 - 0.096 12.3 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Bac_DnaA PF00308.13 CEH17517.1 - 0.1 12.1 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein Arch_ATPase PF01637.13 CEH17517.1 - 0.12 12.1 0.0 4.8 6.8 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase KaiC PF06745.8 CEH17517.1 - 0.13 11.3 0.1 0.81 8.7 0.0 2.1 1 1 1 2 2 2 0 KaiC SKI PF01202.17 CEH17517.1 - 0.14 12.0 0.1 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase C2 PF00168.25 CEH17519.1 - 4.2e-58 193.1 0.3 3.7e-16 58.7 0.0 4.6 4 0 0 4 4 4 4 C2 domain NT-C2 PF10358.4 CEH17519.1 - 0.002 17.6 0.2 0.45 10.0 0.0 3.3 3 0 0 3 3 3 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2404 PF10296.4 CEH17519.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Sigma54_CBD PF04963.8 CEH17519.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain Ras PF00071.17 CEH17520.1 - 2.5e-54 183.0 0.0 2.9e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH17520.1 - 7.1e-20 71.6 0.0 9.8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH17520.1 - 4.6e-07 29.2 0.0 5.1e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEH17520.1 - 0.00021 20.7 0.1 0.0015 17.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CEH17520.1 - 0.00036 19.7 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CEH17520.1 - 0.003 17.4 0.0 0.0046 16.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEH17520.1 - 0.0041 16.4 0.1 0.023 14.0 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 CEH17520.1 - 0.0067 15.6 0.0 0.0095 15.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 CEH17520.1 - 0.037 13.4 0.1 0.058 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain Ion_trans_2 PF07885.11 CEH17523.1 - 2.9e-28 97.4 20.8 4.8e-14 51.8 1.9 2.6 2 0 0 2 2 2 2 Ion channel Ank_4 PF13637.1 CEH17524.1 - 1.1e-12 48.0 1.3 2e-06 28.1 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CEH17524.1 - 6.5e-11 42.4 1.0 2.4e-05 24.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CEH17524.1 - 4.5e-09 35.6 5.2 0.00043 19.9 0.4 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CEH17524.1 - 1.8e-08 34.3 5.4 0.0018 18.4 0.6 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH17524.1 - 5.8e-07 29.1 2.2 0.035 14.3 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 CEH17524.1 - 0.0038 16.8 0.2 0.041 13.4 0.1 2.1 1 1 0 1 1 1 1 KilA-N domain DUF972 PF06156.8 CEH17524.1 - 0.27 11.6 1.6 0.56 10.5 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Pyr_redox_3 PF13738.1 CEH17525.1 - 4.9e-22 78.9 0.0 8.9e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CEH17525.1 - 9.5e-14 50.4 0.1 7.3e-12 44.2 0.0 2.8 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CEH17525.1 - 3.9e-09 35.8 0.0 2.5e-07 29.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CEH17525.1 - 9.2e-08 32.2 0.0 0.00016 21.6 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH17525.1 - 7.4e-07 29.1 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CEH17525.1 - 0.00011 21.9 0.8 0.15 11.8 0.6 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 CEH17525.1 - 0.00034 20.9 0.1 0.059 13.7 0.2 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CEH17525.1 - 0.00059 19.9 0.1 0.17 12.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 CEH17525.1 - 0.0013 17.7 0.1 0.23 10.3 0.0 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 CEH17525.1 - 0.084 11.9 0.2 0.45 9.5 0.1 1.9 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 CEH17525.1 - 0.21 10.5 0.4 0.39 9.7 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.11 CEH17526.1 - 3.3e-37 128.0 37.2 1.5e-33 115.9 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH17526.1 - 3.6e-27 95.0 13.5 3.9e-26 91.6 9.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter PhoD PF09423.5 CEH17527.1 - 0.0022 16.6 0.0 0.016 13.7 0.0 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase SLX9 PF15341.1 CEH17528.1 - 3.7e-09 37.0 10.7 3.7e-09 37.0 7.4 1.9 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 SurA_N_2 PF13623.1 CEH17528.1 - 0.063 13.2 0.5 0.093 12.7 0.4 1.2 1 0 0 1 1 1 0 SurA N-terminal domain DUF3464 PF11947.3 CEH17528.1 - 6.9 6.1 8.7 0.94 8.9 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3464) HA2 PF04408.18 CEH17529.1 - 6.2e-19 67.9 0.0 2.6e-18 65.8 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CEH17529.1 - 2.9e-14 52.8 0.0 6.9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CEH17529.1 - 1.5e-12 47.2 0.0 5.1e-12 45.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEH17529.1 - 2.3e-05 23.9 0.0 0.0002 20.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEH17529.1 - 0.00015 21.9 0.0 0.00047 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CEH17529.1 - 0.027 13.5 0.1 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 CEH17529.1 - 0.036 14.4 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CEH17529.1 - 0.064 12.1 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CEH17529.1 - 0.19 11.2 0.4 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-H2C2_2 PF13465.1 CEH17530.1 - 0.00022 21.3 3.1 0.1 12.9 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 CEH17530.1 - 0.012 15.9 0.3 0.012 15.9 0.2 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 CEH17530.1 - 0.034 14.2 2.3 0.034 14.2 1.6 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.5 CEH17530.1 - 0.068 13.7 0.3 0.21 12.1 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GAGA PF09237.6 CEH17530.1 - 0.17 11.4 6.7 0.082 12.5 2.9 1.8 1 1 0 1 1 1 0 GAGA factor zf-C2H2_4 PF13894.1 CEH17530.1 - 0.44 10.9 7.5 7.7 7.1 0.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEH17530.1 - 0.94 9.7 3.1 5.4 7.3 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CEH17530.1 - 1.3 9.3 5.5 23 5.4 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Ofd1_CTDD PF10637.4 CEH17531.1 - 4.9e-87 291.4 0.0 7.1e-81 271.2 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CEH17531.1 - 1.8e-15 57.2 0.0 4.2e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily His_Phos_1 PF00300.17 CEH17531.1 - 1.3e-13 51.3 0.0 2.9e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 2OG-FeII_Oxy_4 PF13661.1 CEH17531.1 - 0.022 14.4 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Septin PF00735.13 CEH17532.1 - 2.9e-27 95.4 0.0 1.5e-07 30.7 0.0 4.7 5 0 0 5 5 5 4 Septin FtsK_SpoIIIE PF01580.13 CEH17532.1 - 8.7e-05 22.0 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 CEH17532.1 - 0.00026 21.0 0.2 0.0011 18.9 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 CEH17532.1 - 0.027 13.0 0.0 0.069 11.7 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.13 CEH17532.1 - 0.028 13.9 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 CEH17532.1 - 0.047 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 CEH17532.1 - 0.067 12.1 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 CEH17532.1 - 0.22 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 CEH17532.1 - 0.23 10.1 0.1 0.4 9.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit UvrD-helicase PF00580.16 CEH17532.1 - 0.25 10.5 0.1 0.41 9.8 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PPR_3 PF13812.1 CEH17533.1 - 0.00079 19.5 3.6 0.72 10.2 0.0 5.5 7 0 0 7 7 7 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 CEH17533.1 - 0.0047 16.8 0.0 0.73 9.8 0.0 3.2 4 0 0 4 4 4 1 PPR repeat family FAT PF02259.18 CEH17533.1 - 0.091 11.7 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 FAT domain PPR PF01535.15 CEH17533.1 - 0.16 12.0 0.1 4.3 7.5 0.0 3.0 3 0 0 3 3 3 0 PPR repeat RXT2_N PF08595.6 CEH17534.1 - 7.7 6.2 10.2 0.78 9.5 0.1 3.3 3 0 0 3 3 3 0 RXT2-like, N-terminal DUF1741 PF08427.5 CEH17535.1 - 7.4e-30 104.1 0.0 1.3e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) CBFD_NFYB_HMF PF00808.18 CEH17536.1 - 2.7e-15 56.1 0.1 4.4e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CEH17536.1 - 2.3e-10 40.4 0.1 3.3e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 KfrA_N PF11740.3 CEH17536.1 - 0.038 14.4 0.8 0.11 12.9 0.3 2.0 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term Peptidase_S10 PF00450.17 CEH17537.1 - 4.3e-76 256.7 0.0 5.2e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase UDPG_MGDP_dh_N PF03721.9 CEH17538.1 - 2.4e-53 180.2 0.0 7.7e-53 178.6 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 CEH17538.1 - 3.1e-36 123.7 0.0 8.8e-35 119.0 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 CEH17538.1 - 1e-31 108.9 0.0 2e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_7 PF13241.1 CEH17538.1 - 0.023 14.9 0.1 0.79 10.0 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 CEH17538.1 - 0.068 13.1 0.3 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding F420_oxidored PF03807.12 CEH17538.1 - 0.1 13.0 0.3 8.7 6.8 0.0 3.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.16 CEH17540.1 - 2e-72 243.7 0.6 2.7e-72 243.2 0.4 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CEH17540.1 - 2.5e-44 150.0 0.0 4.9e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 CEH17540.1 - 0.011 15.9 0.0 0.04 14.1 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Pkinase PF00069.20 CEH17541.1 - 2.1e-67 226.9 0.0 3.3e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17541.1 - 2e-47 161.4 0.0 3e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH17541.1 - 1.5e-08 33.9 0.0 6.6e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CEH17541.1 - 0.003 16.6 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ras_bdg_2 PF14847.1 CEH17541.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Seadorna_VP7 PF07387.6 CEH17541.1 - 0.087 11.6 0.1 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 CEH17541.1 - 0.49 9.7 0.0 0.9 8.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PCI PF01399.22 CEH17543.1 - 1.8e-16 60.3 0.0 7.6e-16 58.3 0.0 2.1 1 0 0 1 1 1 1 PCI domain TPR_16 PF13432.1 CEH17543.1 - 0.023 15.3 0.0 3.6 8.3 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1136 PF06582.7 CEH17543.1 - 0.026 14.2 0.4 0.55 9.9 0.0 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) PCI_Csn8 PF10075.4 CEH17543.1 - 0.035 13.8 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 DUF3579 PF12112.3 CEH17545.1 - 0.0025 17.6 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3579) Mito_carr PF00153.22 CEH17546.1 - 1e-56 188.5 0.8 3.1e-20 71.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GST_N_3 PF13417.1 CEH17547.1 - 0.0011 19.1 0.0 0.0025 18.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEH17547.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEH17547.1 - 0.055 13.6 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF1917 PF08939.5 CEH17548.1 - 2.1e-15 57.1 0.0 3.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Xan_ur_permease PF00860.15 CEH17549.1 - 2e-52 178.0 29.0 2.7e-35 121.6 8.0 2.1 2 0 0 2 2 2 2 Permease family Nramp PF01566.13 CEH17550.1 - 1.8e-83 280.3 35.1 9.6e-44 149.6 12.5 2.9 2 1 0 2 2 2 2 Natural resistance-associated macrophage protein Abhydrolase_6 PF12697.2 CEH17552.1 - 3.9e-29 102.1 6.3 4.8e-29 101.8 4.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH17552.1 - 8.5e-15 54.9 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH17552.1 - 1.1e-13 51.1 0.1 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CEH17552.1 - 6.6e-07 29.0 0.1 1.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CEH17552.1 - 0.0011 19.2 0.0 0.24 11.5 0.0 2.4 2 1 0 2 2 2 1 Thioesterase domain DUF3530 PF12048.3 CEH17552.1 - 0.014 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Ndr PF03096.9 CEH17552.1 - 0.017 13.6 0.0 0.023 13.2 0.0 1.1 1 0 0 1 1 1 0 Ndr family Rep_fac_C PF08542.6 CEH17553.1 - 5e-23 80.9 0.0 9.5e-23 80.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 CEH17553.1 - 4.5e-12 46.2 0.0 7.1e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CEH17553.1 - 2.3e-11 43.6 0.0 6.5e-10 38.8 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 CEH17553.1 - 5.1e-07 29.6 0.0 7.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEH17553.1 - 1.5e-06 28.3 0.0 2.8e-05 24.1 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 CEH17553.1 - 6.2e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CEH17553.1 - 1.5e-05 23.9 0.0 0.0055 15.4 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CEH17553.1 - 1.9e-05 24.8 0.1 0.077 13.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 CEH17553.1 - 5.8e-05 22.2 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CEH17553.1 - 0.0007 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CEH17553.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 CEH17553.1 - 0.0036 16.8 0.0 0.44 9.9 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 CEH17553.1 - 0.0066 15.6 0.0 0.064 12.4 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 CEH17553.1 - 0.0086 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 CEH17553.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_11 PF13086.1 CEH17553.1 - 0.012 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CEH17553.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 CEH17553.1 - 0.016 14.0 0.0 0.067 11.9 0.0 1.9 1 1 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 CEH17553.1 - 0.034 13.8 0.1 0.14 11.8 0.0 1.9 1 1 1 2 2 2 0 NTPase SRP54 PF00448.17 CEH17553.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain WD40 PF00400.27 CEH17554.1 - 1.5e-48 160.9 8.2 4.5e-11 42.1 0.1 6.4 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CEH17554.1 - 2.5e-05 24.0 8.6 0.37 10.4 0.0 4.7 2 2 3 5 5 5 2 Transcription factor IIIC subunit delta N-term Nbas_N PF15492.1 CEH17554.1 - 0.0086 15.2 1.4 0.047 12.8 0.1 2.4 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal CbiG_N PF11760.3 CEH17554.1 - 0.081 12.6 0.2 6 6.6 0.1 2.6 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal DUF2232 PF09991.4 CEH17555.1 - 0.051 12.5 0.2 0.09 11.7 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF972 PF06156.8 CEH17555.1 - 0.59 10.4 3.4 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 CEH17555.1 - 1.4 8.9 8.2 9.5 6.2 1.0 2.6 2 0 0 2 2 2 0 bZIP transcription factor DUF4200 PF13863.1 CEH17555.1 - 1.5 8.7 9.3 17 5.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) NYD-SP28_assoc PF14775.1 CEH17555.1 - 2.9 7.6 7.2 2.3 7.9 0.7 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain Aldedh PF00171.17 CEH17557.1 - 5.5e-178 592.0 0.3 6.2e-178 591.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldo_ket_red PF00248.16 CEH17558.1 - 8.8e-63 211.7 0.0 1e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1399 PF07173.7 CEH17563.1 - 7.2e-18 65.1 0.5 1.6e-14 54.3 0.0 3.8 3 1 1 4 4 4 2 Protein of unknown function (DUF1399) Corona_NS1 PF06145.6 CEH17563.1 - 0.013 14.8 0.1 0.024 13.9 0.1 1.5 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 Acyl-CoA_dh_1 PF00441.19 CEH17564.1 - 2.4e-45 154.3 1.3 2.4e-45 154.3 0.9 1.9 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CEH17564.1 - 2e-25 89.5 1.7 4.4e-25 88.4 0.1 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CEH17564.1 - 4.5e-21 75.5 0.3 4.5e-21 75.5 0.2 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEH17564.1 - 1.2e-18 66.3 0.0 2.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AgrD PF05931.6 CEH17564.1 - 0.023 14.3 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal AgrD protein Chromo PF00385.19 CEH17565.1 - 0.00015 21.3 0.1 0.0003 20.4 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4412 PF14371.1 CEH17565.1 - 0.1 13.1 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) Macoilin PF09726.4 CEH17567.1 - 1.1 7.4 33.8 0.45 8.7 4.8 2.3 2 0 0 2 2 2 0 Transmembrane protein SNARE PF05739.14 CEH17568.1 - 3.8e-10 39.2 0.7 6.4e-10 38.5 0.5 1.4 1 0 0 1 1 1 1 SNARE domain DUF4407 PF14362.1 CEH17568.1 - 0.025 13.5 1.0 0.035 13.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF384 PF04064.8 CEH17568.1 - 0.043 13.3 1.4 0.073 12.6 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF384) SWIRM PF04433.12 CEH17569.1 - 2.4e-13 50.0 0.0 5.6e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain DUF3306 PF11748.3 CEH17569.1 - 0.43 11.2 12.6 0.12 13.0 1.1 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3306) ZZ PF00569.12 CEH17570.1 - 7.7e-13 47.7 5.7 1.4e-12 46.9 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CEH17570.1 - 1.6e-09 37.6 0.0 3.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH17570.1 - 0.0008 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain zinc-ribbons_6 PF07191.7 CEH17570.1 - 0.34 10.7 4.5 0.74 9.6 3.1 1.5 1 0 0 1 1 1 0 zinc-ribbons DNA_RNApol_7kD PF03604.8 CEH17570.1 - 9 5.8 10.1 0.19 11.2 2.1 1.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit OTCace_N PF02729.16 CEH17571.1 - 3e-42 143.6 0.0 6.1e-42 142.6 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 CEH17571.1 - 3e-41 140.9 0.0 4.4e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF4451 PF14616.1 CEH17572.1 - 4.3e-17 62.0 0.3 9.1e-08 31.9 0.1 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4451) HEAT_EZ PF13513.1 CEH17574.1 - 3.6e-33 113.1 12.8 1.3e-07 31.8 0.0 11.7 11 2 2 13 13 11 6 HEAT-like repeat HEAT_2 PF13646.1 CEH17574.1 - 6.3e-20 71.2 16.1 0.0009 19.4 0.3 8.4 5 3 5 10 10 10 7 HEAT repeats HEAT PF02985.17 CEH17574.1 - 1.1e-15 56.2 22.9 0.0019 18.1 0.1 11.0 12 0 0 12 12 11 4 HEAT repeat UME PF08064.8 CEH17574.1 - 4e-11 42.8 0.0 0.012 15.5 0.0 6.1 4 3 1 5 5 5 3 UME (NUC010) domain IBN_N PF03810.14 CEH17574.1 - 3e-08 33.4 0.0 1.1e-07 31.6 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 CEH17574.1 - 3.3e-08 32.3 1.5 0.012 13.9 0.0 4.6 4 1 2 6 6 6 4 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CEH17574.1 - 1.7e-07 31.5 0.0 2.2 8.7 0.0 5.7 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 CEH17574.1 - 4e-07 29.9 0.0 0.037 13.9 0.0 5.6 6 1 1 7 7 7 2 Rix1 complex component involved in 60S ribosome maturation RIX1 PF08167.7 CEH17574.1 - 8e-07 28.8 0.0 3 7.4 0.0 5.4 5 1 0 5 5 5 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 CEH17574.1 - 1.1e-05 24.9 0.0 0.048 12.9 0.0 4.7 4 1 0 5 5 5 1 CLASP N terminal Cohesin_HEAT PF12765.2 CEH17574.1 - 1.9e-05 24.4 0.7 0.44 10.5 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion DUF3437 PF11919.3 CEH17574.1 - 0.00012 21.6 0.1 0.029 14.0 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) Cnd1 PF12717.2 CEH17574.1 - 0.00021 21.1 0.0 12 5.7 0.0 4.7 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 CEH17574.1 - 0.0092 15.8 0.0 0.21 11.5 0.0 2.9 1 1 1 2 2 2 1 Parkin co-regulated protein DUF2267 PF10025.4 CEH17574.1 - 0.048 13.7 1.1 0.4 10.7 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) DUF2435 PF10363.4 CEH17574.1 - 0.052 13.4 1.4 18 5.3 0.0 5.1 5 1 1 6 6 6 0 Protein of unknown function (DUF2435) DUF2454 PF10521.4 CEH17574.1 - 0.18 10.8 0.3 23 3.8 0.0 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF2454) adh_short PF00106.20 CEH17578.1 - 2.3e-07 30.8 0.2 4.8e-07 29.8 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH17578.1 - 2.3e-06 27.5 0.0 3.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH17578.1 - 0.0006 19.5 0.1 0.00098 18.8 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CEH17578.1 - 0.0025 17.5 0.2 0.0038 16.8 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CEH17578.1 - 0.0035 17.2 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 CEH17578.1 - 0.036 14.0 0.5 0.084 12.8 0.3 1.6 1 1 0 1 1 1 0 NADH(P)-binding F420_oxidored PF03807.12 CEH17578.1 - 0.09 13.2 0.2 0.16 12.4 0.2 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_6 PF12697.2 CEH17579.1 - 4.4e-29 101.9 2.3 4.4e-29 101.9 1.6 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH17579.1 - 7.6e-16 58.3 0.0 4e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH17579.1 - 8.8e-15 54.7 0.3 2.3e-10 40.4 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CEH17579.1 - 2.5e-06 27.1 0.1 0.00018 21.1 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 CEH17579.1 - 8.7e-06 25.3 0.1 1.7e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 CEH17579.1 - 0.00023 20.9 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 CEH17579.1 - 0.00031 20.2 0.0 0.035 13.5 0.0 2.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 CEH17579.1 - 0.0027 16.6 0.0 0.012 14.5 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.8 CEH17579.1 - 0.0028 17.2 0.0 0.0073 15.9 0.0 1.7 1 0 0 1 1 1 1 Serine hydrolase DUF915 PF06028.6 CEH17579.1 - 0.0052 15.9 0.0 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.9 CEH17579.1 - 0.012 14.1 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.3 CEH17579.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Chlorophyllase PF07224.6 CEH17579.1 - 0.019 13.7 0.0 0.13 11.0 0.0 2.0 1 1 0 1 1 1 0 Chlorophyllase DUF2305 PF10230.4 CEH17579.1 - 0.038 13.4 0.0 0.15 11.4 0.0 2.0 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 CEH17579.1 - 0.049 13.2 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 CEH17579.1 - 0.081 12.1 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PolyA_pol PF01743.15 CEH17580.1 - 9.4e-19 67.8 0.0 6.3e-18 65.1 0.0 2.2 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CEH17580.1 - 6.4e-06 25.6 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF3633 PF12315.3 CEH17581.1 - 0.042 13.1 0.1 0.064 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) cEGF PF12662.2 CEH17581.1 - 0.14 11.7 2.3 0.31 10.7 1.6 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like RTBV_P12 PF06361.6 CEH17581.1 - 1.7 8.8 4.5 0.53 10.5 0.8 1.8 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein Pacs-1 PF10254.4 CEH17581.1 - 4 5.9 5.8 5.8 5.4 4.0 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Macoilin PF09726.4 CEH17581.1 - 5 5.2 4.9 4.8 5.3 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein PLDc_2 PF13091.1 CEH17582.1 - 1.2e-17 63.8 0.0 1.4e-07 31.3 0.0 3.3 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.17 CEH17582.1 - 1e-15 56.8 2.5 3.8e-08 32.8 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Sugar_tr PF00083.19 CEH17583.1 - 4.8e-32 111.1 23.3 1.1e-17 63.7 6.3 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEH17583.1 - 7.5e-25 87.3 64.9 2.6e-20 72.4 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 CEH17585.1 - 1.1e-28 99.1 1.3 3.4e-28 97.5 0.9 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEH17585.1 - 5.4e-23 80.9 0.7 8.4e-23 80.3 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEH17585.1 - 0.014 14.5 0.2 0.025 13.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TAF4 PF05236.9 CEH17587.1 - 7.5e-25 87.6 2.7 7.5e-25 87.6 1.9 3.5 3 0 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.2 CEH17587.1 - 0.0015 18.2 21.0 0.0015 18.2 14.5 3.1 1 1 1 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Fungal_trans PF04082.13 CEH17588.1 - 1.6e-23 82.9 0.0 3.7e-23 81.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH17588.1 - 4.1e-08 33.0 7.2 1e-07 31.7 5.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 CEH17589.1 - 1.2e-05 25.0 8.9 2.8e-05 23.9 6.2 1.6 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CEH17589.1 - 0.0055 15.6 0.0 0.051 12.4 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain DJ-1_PfpI PF01965.19 CEH17590.1 - 7.6e-29 100.0 0.1 1.3e-28 99.3 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 CEH17590.1 - 3.5e-14 52.0 0.1 9.9e-14 50.5 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family FA_desaturase PF00487.19 CEH17591.1 - 5.1e-28 98.2 19.5 2.2e-15 56.7 3.9 2.1 2 0 0 2 2 2 2 Fatty acid desaturase DUF3474 PF11960.3 CEH17591.1 - 2.3e-05 24.4 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FHA PF00498.21 CEH17592.1 - 2e-13 50.2 0.0 3.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CEH17592.1 - 4.4e-08 32.8 14.3 6.8e-08 32.2 9.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CEH17592.1 - 0.00033 20.7 7.9 0.00061 19.8 5.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CEH17592.1 - 0.011 15.6 5.5 0.019 14.8 3.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CEH17592.1 - 0.014 15.0 13.0 0.022 14.4 9.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH17592.1 - 0.11 12.1 12.0 0.2 11.4 8.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CEH17592.1 - 0.41 10.7 15.2 0.65 10.0 10.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CEH17592.1 - 1.5 8.5 8.3 2.7 7.7 5.8 1.4 1 0 0 1 1 1 0 PHD-finger AMP-binding PF00501.23 CEH17593.1 - 3.9e-83 279.1 0.0 5e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEH17593.1 - 1.7e-10 41.6 0.1 4.3e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ERG2_Sigma1R PF04622.7 CEH17594.1 - 2.8e-77 258.8 0.1 3.1e-77 258.6 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein MBOAT_2 PF13813.1 CEH17595.1 - 1.4e-16 60.2 2.1 9.1e-15 54.5 0.2 3.2 2 1 0 2 2 2 2 Membrane bound O-acyl transferase family AA_permease PF00324.16 CEH17596.1 - 8.7e-106 354.1 38.9 1.1e-105 353.7 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CEH17596.1 - 6.5e-24 84.2 40.4 9.7e-24 83.6 28.0 1.2 1 1 0 1 1 1 1 Amino acid permease Zn_clus PF00172.13 CEH17597.1 - 3.8e-07 29.8 10.5 1.6e-06 27.9 7.3 1.9 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF836 PF05768.9 CEH17599.1 - 2.4e-11 43.7 0.0 3.5e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) N2227 PF07942.7 CEH17600.1 - 1.8e-91 305.8 0.0 2.6e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein DNAP_B_exo_N PF08452.5 CEH17601.1 - 0.0053 15.9 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B exonuclease domain, N-terminal Aldedh PF00171.17 CEH17602.1 - 1.9e-154 514.4 0.3 2.2e-154 514.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CEH17602.1 - 0.12 11.5 0.0 10 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Pyridoxal_deC PF00282.14 CEH17603.1 - 6.3e-96 321.0 0.0 1.4e-95 319.9 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Complex1_LYR_2 PF13233.1 CEH17604.1 - 2.4e-06 27.9 0.6 3.4e-06 27.4 0.1 1.5 2 0 0 2 2 2 1 Complex1_LYR-like HR1 PF02185.11 CEH17604.1 - 0.39 10.4 4.2 8.8 6.1 0.0 3.1 3 0 0 3 3 3 0 Hr1 repeat TFIID-31kDa PF02291.10 CEH17605.1 - 2.7e-30 104.7 0.0 5.5e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 CEH17605.1 - 0.0005 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 CEH17605.1 - 0.066 12.4 14.0 0.014 14.6 6.5 1.8 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T DUF4565 PF15127.1 CEH17605.1 - 0.067 13.5 0.5 1.7 9.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4565) SURF2 PF05477.6 CEH17605.1 - 7.6 5.5 10.3 11 5.0 7.1 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.7 CEH17605.1 - 9.7 3.9 15.8 13 3.5 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family Cript PF10235.4 CEH17606.1 - 1.1e-17 64.0 4.5 1.1e-17 64.0 3.1 1.9 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 CEH17606.1 - 0.1 12.4 13.0 0.64 9.8 5.0 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 CEH17606.1 - 0.13 11.5 9.1 0.26 10.5 1.7 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-dskA_traR PF01258.12 CEH17606.1 - 0.38 10.5 0.0 0.38 10.5 0.0 2.8 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger Atrophin-1 PF03154.10 CEH17606.1 - 0.67 8.0 3.8 0.8 7.7 2.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family XPA_N PF01286.13 CEH17606.1 - 0.68 9.6 4.8 6 6.6 0.1 3.1 3 0 0 3 3 3 0 XPA protein N-terminal DUF2039 PF10217.4 CEH17606.1 - 0.8 9.7 11.5 0.16 11.9 3.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1272 PF06906.6 CEH17606.1 - 1.3 8.8 6.7 2.9 7.7 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C3HC4_3 PF13920.1 CEH17606.1 - 3.6 7.3 10.2 40 3.9 4.6 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-BED PF02892.10 CEH17606.1 - 4.7 7.0 15.2 3.8 7.3 0.2 3.5 2 1 1 3 3 3 0 BED zinc finger C1_1 PF00130.17 CEH17606.1 - 5.4 6.8 12.6 8.6 6.1 2.5 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NinF PF05810.7 CEH17606.1 - 7.1 6.5 7.6 18 5.2 0.7 2.5 2 1 0 2 2 2 0 NinF protein Gin PF10764.4 CEH17606.1 - 9.4 6.0 8.1 18 5.1 0.1 2.6 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin Peptidase_M24 PF00557.19 CEH17608.1 - 2.3e-45 154.7 0.0 3.5e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CEH17608.1 - 3.9e-35 120.1 0.0 6.5e-35 119.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF2945 PF11160.3 CEH17608.1 - 0.021 14.6 0.1 7.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2945) ThiF PF00899.16 CEH17609.1 - 9.5e-42 142.0 0.5 1.5e-41 141.3 0.4 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CEH17609.1 - 1.7e-23 81.9 0.0 3.6e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 CEH17609.1 - 2.7e-06 27.5 0.1 7.6e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Rhodanese PF00581.15 CEH17609.1 - 1e-05 25.8 0.0 2.4e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain NAD_binding_7 PF13241.1 CEH17609.1 - 0.0026 17.9 0.1 0.0054 16.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 CEH17609.1 - 0.035 13.0 0.3 0.054 12.4 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DAO PF01266.19 CEH17609.1 - 0.046 12.6 0.3 0.084 11.7 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CEH17609.1 - 0.092 12.7 0.1 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 60KD_IMP PF02096.15 CEH17611.1 - 6e-24 84.7 0.0 8.6e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_S4 PF00163.14 CEH17612.1 - 2.4e-10 40.6 2.2 3.5e-10 40.1 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CEH17612.1 - 2.5e-07 30.0 0.0 4.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF530 PF04409.7 CEH17612.1 - 0.015 13.3 0.1 0.02 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) PI-PLC-X PF00388.14 CEH17612.1 - 0.071 12.4 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain CoA_binding PF02629.14 CEH17613.1 - 5.5e-29 100.5 0.3 4e-28 97.7 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CEH17613.1 - 2.5e-21 75.8 0.0 4.2e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CEH17613.1 - 2.1e-08 33.8 0.0 4.5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CEH17613.1 - 7.9e-05 22.8 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 CEH17613.1 - 0.0014 19.0 0.0 0.0048 17.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Synthase_beta PF11421.3 CEH17613.1 - 0.14 12.7 3.3 0.34 11.5 2.3 1.6 1 0 0 1 1 1 0 ATP synthase F1 beta subunit PIG-U PF06728.8 CEH17614.1 - 5.6e-93 311.8 20.9 6.7e-93 311.5 14.5 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Flavin_Reduct PF01613.13 CEH17614.1 - 0.0023 17.7 3.1 0.0049 16.7 0.5 2.2 2 0 0 2 2 2 1 Flavin reductase like domain SH3_1 PF00018.23 CEH17615.1 - 3.9e-15 54.9 0.2 5.6e-15 54.4 0.1 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEH17615.1 - 6.6e-11 41.6 0.2 9.3e-11 41.1 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEH17615.1 - 2.5e-09 36.4 0.0 4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CEH17615.1 - 0.061 13.5 0.3 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Cupin_8 PF13621.1 CEH17616.1 - 2.4e-17 63.2 0.0 4.4e-17 62.4 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CEH17616.1 - 3.1e-13 49.9 0.2 1e-08 35.4 0.1 2.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase Acetyltransf_1 PF00583.19 CEH17617.1 - 3.4e-08 33.3 0.2 8.7e-08 32.0 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEH17617.1 - 7.5e-08 32.4 0.0 1.7e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEH17617.1 - 0.0001 22.1 0.0 0.00083 19.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CEH17617.1 - 0.0019 18.3 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEH17617.1 - 0.0057 16.3 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_6 PF13480.1 CEH17617.1 - 0.073 13.0 0.3 0.21 11.5 0.2 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CEH17617.1 - 0.085 12.8 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SCAMP PF04144.8 CEH17618.1 - 1.1e-42 145.8 7.4 1.3e-42 145.6 5.1 1.0 1 0 0 1 1 1 1 SCAMP family DUF4061 PF13270.1 CEH17618.1 - 0.0089 16.0 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) DUF4200 PF13863.1 CEH17618.1 - 0.13 12.2 3.9 0.19 11.6 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Peptidase_S8 PF00082.17 CEH17620.1 - 4.9e-47 160.4 0.2 9.8e-47 159.4 0.1 1.6 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 CEH17620.1 - 0.0016 18.1 0.0 0.0049 16.5 0.0 1.8 1 0 0 1 1 1 1 PA domain Raffinose_syn PF05691.7 CEH17621.1 - 8.4e-05 20.3 0.0 0.0014 16.3 0.0 2.4 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 His_Phos_2 PF00328.17 CEH17624.1 - 3.9e-26 92.2 0.0 1.1e-25 90.7 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 CEH17624.1 - 0.0038 17.3 0.0 0.031 14.3 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ING PF12998.2 CEH17626.1 - 1.9e-09 37.7 0.0 2.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CEH17626.1 - 7.6e-08 31.9 9.2 1.2e-07 31.3 6.4 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CEH17626.1 - 0.03 14.4 0.2 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 CEH17626.1 - 0.15 11.4 3.5 0.26 10.6 2.4 1.4 1 0 0 1 1 1 0 PHD-finger Abhydrolase_6 PF12697.2 CEH17627.1 - 3.2e-28 99.1 0.0 7.7e-28 97.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH17627.1 - 1.2e-16 60.9 0.1 2e-16 60.2 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH17627.1 - 2.6e-16 59.6 0.0 3.8e-16 59.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CEH17627.1 - 9.6e-10 38.4 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 CEH17627.1 - 2.4e-05 24.0 0.6 0.00012 21.8 0.2 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 CEH17627.1 - 0.00072 18.5 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF676 PF05057.9 CEH17627.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 CEH17627.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CEH17627.1 - 0.0071 16.5 0.0 0.0092 16.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase PF07224.6 CEH17627.1 - 0.0083 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Lipase_3 PF01764.20 CEH17627.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3089 PF11288.3 CEH17627.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DLH PF01738.13 CEH17627.1 - 0.016 14.5 0.0 0.091 12.0 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 CEH17627.1 - 0.056 11.7 0.2 2.8 6.1 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II OmdA PF13376.1 CEH17628.1 - 2.4e-14 52.7 1.6 2.4e-14 52.7 1.1 1.7 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated CRAL_TRIO PF00650.15 CEH17629.1 - 2.1e-25 89.0 0.0 3.1e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CEH17629.1 - 9.4e-07 28.8 0.0 1.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain WD40 PF00400.27 CEH17630.1 - 2.2e-27 93.8 9.8 4.9e-08 32.5 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 CEH17630.1 - 0.00012 20.3 0.0 0.24 9.4 0.0 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 NUDE_C PF04880.8 CEH17631.1 - 1.1e-15 58.4 3.7 1.1e-15 58.4 2.5 4.6 4 1 0 4 4 4 1 NUDE protein, C-terminal conserved region ATG16 PF08614.6 CEH17631.1 - 0.16 11.7 27.7 0.96 9.2 16.1 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Tmemb_cc2 PF10267.4 CEH17631.1 - 0.19 10.2 16.5 0.79 8.2 0.2 2.4 1 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein AAA_27 PF13514.1 CEH17631.1 - 0.45 8.1 28.9 0.82 7.2 20.0 1.3 1 1 0 1 1 1 0 AAA domain IncA PF04156.9 CEH17631.1 - 2.4 7.6 27.5 3 7.4 10.4 2.4 1 1 1 2 2 2 0 IncA protein Sec8_exocyst PF04048.9 CEH17631.1 - 2.4 7.7 12.8 0.36 10.4 0.1 3.2 1 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Prefoldin PF02996.12 CEH17631.1 - 3.2 7.4 21.2 0.85 9.2 0.4 4.5 4 1 1 5 5 5 0 Prefoldin subunit SlyX PF04102.7 CEH17631.1 - 3.7 7.9 19.1 21 5.5 0.9 4.7 3 1 1 4 4 4 0 SlyX gpD PF02925.11 CEH17632.1 - 0.045 13.5 0.5 0.096 12.4 0.3 1.5 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D NUDIX PF00293.23 CEH17633.1 - 1.5e-14 53.8 0.1 5.2e-14 52.0 0.1 1.8 1 1 0 1 1 1 1 NUDIX domain Septin PF00735.13 CEH17634.1 - 2.2e-110 368.1 0.4 2.8e-110 367.7 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CEH17634.1 - 1.8e-09 37.5 0.0 7e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CEH17634.1 - 3.9e-06 26.7 0.2 0.035 13.9 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 CEH17634.1 - 5.7e-06 25.5 0.4 1.2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 CEH17634.1 - 6.5e-06 25.4 0.0 1.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 CEH17634.1 - 7.7e-05 22.2 0.1 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 CEH17634.1 - 9.9e-05 21.8 0.3 0.0019 17.6 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CEH17634.1 - 0.0011 19.0 0.1 0.016 15.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CEH17634.1 - 0.002 17.6 0.2 0.0025 17.2 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 CEH17634.1 - 0.0022 18.7 1.9 1.1 10.0 0.1 2.4 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CEH17634.1 - 0.0032 17.7 0.3 0.0099 16.1 0.0 1.9 2 1 0 2 2 2 1 ABC transporter IIGP PF05049.8 CEH17634.1 - 0.0036 16.1 0.1 0.0095 14.7 0.1 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) T2SE PF00437.15 CEH17634.1 - 0.0047 15.8 0.1 0.013 14.3 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 CEH17634.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 CEH17634.1 - 0.0074 16.7 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein DUF87 PF01935.12 CEH17634.1 - 0.0088 15.8 1.0 0.15 11.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Gtr1_RagA PF04670.7 CEH17634.1 - 0.018 14.2 0.1 0.065 12.3 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF815 PF05673.8 CEH17634.1 - 0.018 13.9 0.0 0.036 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CEH17634.1 - 0.031 13.9 0.1 0.089 12.4 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 CEH17634.1 - 0.053 13.0 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CEH17634.1 - 0.06 12.8 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CEH17634.1 - 0.081 11.7 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 CEH17634.1 - 0.082 12.6 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CEH17634.1 - 0.17 11.8 2.9 0.4 10.5 0.0 2.7 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.1 CEH17634.1 - 0.63 10.3 4.3 3.1 8.0 3.0 2.0 1 1 0 1 1 1 0 AAA domain Ribosomal_L7Ae PF01248.21 CEH17635.1 - 2.5e-22 78.1 0.2 4.5e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CEH17635.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 VirionAssem_T7 PF11653.3 CEH17635.1 - 0.6 10.8 13.6 0.49 11.1 0.3 2.6 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein NAM-associated PF14303.1 CEH17635.1 - 0.61 10.4 7.9 0.27 11.5 3.7 1.6 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain LRRCT PF01463.19 CEH17636.1 - 0.45 10.9 2.4 1.3 9.4 0.1 2.6 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain G_glu_transpept PF01019.16 CEH17638.1 - 6.2e-147 490.1 0.2 7.2e-147 489.9 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Evr1_Alr PF04777.8 CEH17639.1 - 5.2e-26 90.3 0.5 1.2e-25 89.1 0.1 1.9 2 0 0 2 2 2 1 Erv1 / Alr family COX16 PF14138.1 CEH17639.1 - 1.2e-21 76.6 0.0 2.5e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 dCMP_cyt_deam_1 PF00383.17 CEH17640.1 - 6.3e-13 48.2 0.1 1.1e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CEH17640.1 - 4.7e-10 39.5 2.2 4e-09 36.5 0.4 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region YwqJ-deaminase PF14431.1 CEH17640.1 - 0.14 12.0 0.3 0.31 10.9 0.2 1.6 1 1 0 1 1 1 0 YwqJ-like deaminase UPF0016 PF01169.14 CEH17641.1 - 2.1e-51 171.9 28.8 1.8e-21 76.0 4.8 3.2 3 0 0 3 3 3 3 Uncharacterized protein family UPF0016 TauE PF01925.14 CEH17641.1 - 0.072 12.5 19.5 0.47 9.8 4.1 2.8 2 1 1 3 3 3 0 Sulfite exporter TauE/SafE DUF4131 PF13567.1 CEH17641.1 - 0.4 10.0 11.4 1.8 7.9 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) NUDIX PF00293.23 CEH17642.1 - 1.1e-10 41.2 0.0 2.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain LCAT PF02450.10 CEH17644.1 - 1.6e-81 274.2 0.6 1.1e-79 268.2 0.4 2.3 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CEH17644.1 - 0.002 18.0 0.6 0.0068 16.3 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH17644.1 - 0.0045 16.7 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DELLA PF12041.3 CEH17644.1 - 0.092 12.4 0.1 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Spc97_Spc98 PF04130.8 CEH17646.1 - 3e-32 111.6 0.0 7.6e-18 64.1 0.0 2.2 2 0 0 2 2 2 2 Spc97 / Spc98 family Prefoldin_2 PF01920.15 CEH17647.1 - 2.2e-18 65.9 5.2 2.2e-18 65.9 3.6 1.5 1 1 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.4 CEH17647.1 - 0.0012 18.7 6.2 0.24 11.2 0.9 2.1 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cluap1 PF10234.4 CEH17647.1 - 0.011 15.0 5.3 0.055 12.6 0.1 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF641 PF04859.7 CEH17647.1 - 0.011 15.4 7.1 0.34 10.6 0.5 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) FliD_C PF07195.7 CEH17647.1 - 0.021 14.1 4.1 0.39 9.9 0.8 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF2937 PF11157.3 CEH17647.1 - 0.024 13.9 1.9 0.038 13.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Spc24 PF08286.6 CEH17647.1 - 0.044 13.4 6.1 0.18 11.5 0.5 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin_3 PF13758.1 CEH17647.1 - 0.088 12.5 1.7 0.37 10.5 1.1 2.1 1 1 0 1 1 1 0 Prefoldin subunit Tropomyosin_1 PF12718.2 CEH17647.1 - 0.1 12.4 10.5 1 9.1 0.9 2.2 2 0 0 2 2 2 0 Tropomyosin like ADIP PF11559.3 CEH17647.1 - 0.11 12.4 10.4 0.14 12.0 0.5 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CEH17647.1 - 0.15 11.6 14.0 0.71 9.4 9.7 1.8 1 1 0 1 1 1 0 IncA protein DUF2046 PF09755.4 CEH17647.1 - 0.15 10.9 5.9 0.064 12.1 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Syntaxin-6_N PF09177.6 CEH17647.1 - 0.17 12.3 5.7 6.5 7.2 1.2 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Prefoldin PF02996.12 CEH17647.1 - 0.18 11.4 6.1 3.5 7.2 0.2 2.5 2 1 0 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.3 CEH17647.1 - 0.29 10.8 6.7 0.17 11.6 0.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YgaB PF14182.1 CEH17647.1 - 0.63 10.3 7.9 0.31 11.2 1.0 2.5 2 1 0 2 2 2 0 YgaB-like protein Filament PF00038.16 CEH17647.1 - 0.71 9.2 7.9 0.2 11.0 1.3 2.0 2 0 0 2 2 2 0 Intermediate filament protein Occludin_ELL PF07303.8 CEH17647.1 - 0.76 10.5 3.6 2.7 8.7 0.1 2.1 2 0 0 2 2 2 0 Occludin homology domain V_ATPase_I PF01496.14 CEH17647.1 - 1 7.1 3.5 0.71 7.6 1.4 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Striatin PF08232.7 CEH17647.1 - 1 9.6 5.6 3.9 7.7 0.3 2.1 2 0 0 2 2 2 0 Striatin family BLOC1_2 PF10046.4 CEH17647.1 - 1.8 8.7 5.7 1.3 9.1 0.8 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin PF00261.15 CEH17647.1 - 2 7.4 9.7 4.4 6.3 1.2 2.1 2 0 0 2 2 2 0 Tropomyosin Kinetocho_Slk19 PF12709.2 CEH17647.1 - 2.1 8.4 9.0 3.8 7.6 0.8 2.4 2 1 0 2 2 2 0 Central kinetochore-associated DUF4140 PF13600.1 CEH17647.1 - 2.5 8.5 9.1 4.5 7.7 1.8 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Syntaxin_2 PF14523.1 CEH17647.1 - 2.7 8.0 9.6 6.2 6.9 0.7 2.3 1 1 0 2 2 2 0 Syntaxin-like protein HrpB7 PF09486.5 CEH17647.1 - 2.9 7.8 9.7 3 7.7 0.1 2.5 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) APG6 PF04111.7 CEH17647.1 - 3.2 6.7 12.0 1 8.3 2.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Mnd1 PF03962.10 CEH17647.1 - 4 7.0 10.0 0.93 9.1 1.4 2.1 1 1 1 2 2 2 0 Mnd1 family DUF3584 PF12128.3 CEH17647.1 - 4 4.6 9.4 7.1 3.8 6.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF848 PF05852.6 CEH17647.1 - 4 7.2 8.9 4.3 7.1 1.1 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF812 PF05667.6 CEH17647.1 - 5.4 5.3 10.5 29 2.9 7.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TMF_DNA_bd PF12329.3 CEH17647.1 - 5.5 6.8 13.0 4.5 7.1 1.0 2.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 CEH17647.1 - 6.2 7.2 8.6 2.2 8.6 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FlxA PF14282.1 CEH17647.1 - 7.5 6.5 17.5 7.9 6.4 2.1 2.2 2 0 0 2 2 2 0 FlxA-like protein Lzipper-MIP1 PF14389.1 CEH17647.1 - 7.8 6.6 10.5 0.43 10.7 1.8 2.4 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TPR_MLP1_2 PF07926.7 CEH17647.1 - 7.9 6.2 14.1 1.3 8.8 3.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FliJ PF02050.11 CEH17647.1 - 8.2 6.5 11.5 3.3 7.7 2.4 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Uds1 PF15456.1 CEH17647.1 - 8.5 6.3 9.6 2.9 7.9 1.8 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Adeno_PIX PF03955.9 CEH17647.1 - 9.3 6.8 7.1 31 5.1 2.8 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) MAM33 PF02330.11 CEH17648.1 - 3.4e-26 92.2 0.1 3.6e-26 92.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein GCN5L1 PF06320.8 CEH17648.1 - 0.082 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Peptidase_S9_N PF02897.10 CEH17650.1 - 1.1e-81 274.6 0.0 1.5e-81 274.1 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CEH17650.1 - 1.1e-49 168.5 0.1 1.7e-49 167.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CEH17650.1 - 0.005 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold ssDNA-exonuc_C PF10141.4 CEH17650.1 - 0.15 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain Glyco_hydro_47 PF01532.15 CEH17651.1 - 6.5e-118 394.2 0.0 7.7e-118 394.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_65m PF03632.10 CEH17652.1 - 8.9e-91 304.3 3.2 3.2e-56 190.6 0.3 3.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain F5_F8_type_C PF00754.20 CEH17652.1 - 0.013 15.3 0.6 0.013 15.3 0.4 3.0 4 1 0 4 4 4 0 F5/8 type C domain Orthopox_A36R PF05950.6 CEH17652.1 - 0.027 14.4 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Glyco_hydro_65C PF03633.10 CEH17652.1 - 0.037 14.0 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain Orthopox_F6 PF06601.7 CEH17654.1 - 0.033 14.1 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 Orthopoxvirus F6 protein CobD_Cbib PF03186.8 CEH17654.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 CobD/Cbib protein HSP70 PF00012.15 CEH17656.1 - 0.00013 20.0 1.8 0.0002 19.4 0.1 2.1 2 1 1 3 3 3 1 Hsp70 protein GTPase_Cys_C PF12631.2 CEH17657.1 - 0.1 12.9 2.5 0.91 9.9 0.2 3.1 2 1 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE HisKA_3 PF07730.8 CEH17657.1 - 0.3 11.4 3.7 1.6 9.1 1.1 3.0 2 1 1 3 3 3 0 Histidine kinase Phage_GP20 PF06810.6 CEH17659.1 - 9.8e-05 21.8 2.1 0.0027 17.1 0.5 2.4 2 0 0 2 2 2 1 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.7 CEH17659.1 - 0.0004 20.1 2.7 0.00073 19.2 0.0 2.4 3 0 0 3 3 2 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 CEH17659.1 - 0.0039 17.0 1.9 2 8.2 0.1 2.5 2 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Sec8_exocyst PF04048.9 CEH17659.1 - 0.0052 16.4 1.6 0.013 15.1 0.1 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Apolipoprotein PF01442.13 CEH17659.1 - 0.0069 15.9 10.3 0.026 14.0 4.7 2.9 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain RHD3 PF05879.7 CEH17659.1 - 0.038 11.9 2.3 0.06 11.2 1.6 1.3 1 1 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF1386 PF07138.6 CEH17659.1 - 0.06 12.4 0.0 0.73 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1386) HalX PF08663.5 CEH17659.1 - 0.069 13.1 3.7 0.11 12.5 0.4 2.7 2 1 1 3 3 3 0 HalX domain Herpes_ICP4_N PF03584.10 CEH17659.1 - 0.069 12.6 0.1 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region DUF1192 PF06698.6 CEH17659.1 - 0.075 12.8 2.5 0.14 11.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) NPV_P10 PF05531.7 CEH17659.1 - 0.25 11.6 2.2 1.3 9.3 0.2 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.7 CEH17659.1 - 0.25 11.2 4.0 2.2 8.2 1.4 3.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4407 PF14362.1 CEH17659.1 - 0.28 10.0 2.8 0.14 11.0 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Laminin_II PF06009.7 CEH17659.1 - 0.33 10.6 5.9 0.19 11.5 1.3 2.2 2 0 0 2 2 2 0 Laminin Domain II Atg14 PF10186.4 CEH17659.1 - 1.4 7.8 10.0 0.083 11.8 1.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CEH17659.1 - 3.5 7.1 13.7 1.5 8.4 1.1 3.1 2 1 1 3 3 3 0 IncA protein SPX PF03105.14 CEH17659.1 - 6.1 6.5 6.5 19 4.9 4.5 1.8 1 1 0 1 1 1 0 SPX domain ALMT PF11744.3 CEH17659.1 - 6.1 5.3 5.9 3.2 6.3 0.2 2.0 1 1 1 2 2 2 0 Aluminium activated malate transporter RBD-FIP PF09457.5 CEH17659.1 - 9.6 6.0 9.0 0.17 11.6 0.4 2.6 3 0 0 3 3 3 0 FIP domain PRELI PF04707.9 CEH17660.1 - 9e-16 57.8 0.0 7.1e-07 28.9 0.0 3.1 3 0 0 3 3 3 3 PRELI-like family MaoC_dehydratas PF01575.14 CEH17661.1 - 0.0013 18.1 0.1 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain p450 PF00067.17 CEH17662.1 - 6.2e-51 173.3 0.0 7.6e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CorA PF01544.13 CEH17664.1 - 5.7e-46 156.8 0.8 7.6e-46 156.4 0.5 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 CEH17664.1 - 0.063 13.1 0.6 0.13 12.0 0.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACT_4 PF13291.1 CEH17664.1 - 0.067 13.5 0.1 0.17 12.2 0.1 1.6 2 0 0 2 2 2 0 ACT domain DUF3826 PF12875.2 CEH17664.1 - 0.22 11.1 0.3 1.9 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) DUF3961 PF13106.1 CEH17664.1 - 0.42 10.2 5.0 0.86 9.2 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Glyco_hydro_cc PF11790.3 CEH17665.1 - 7.6e-51 172.8 1.5 1e-50 172.4 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 CEH17665.1 - 0.011 14.5 0.1 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 CMD PF02627.15 CEH17666.1 - 7.5e-20 70.5 0.2 1.1e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Toxin_30 PF08117.6 CEH17670.1 - 4.6 7.3 5.9 1.3 9.1 1.6 2.0 2 1 0 2 2 2 0 Ptu family DPBB_1 PF03330.13 CEH17671.1 - 0.0098 15.8 0.2 0.0098 15.8 0.1 2.8 3 1 0 3 3 3 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4614 PF15391.1 CEH17671.1 - 0.058 13.1 6.5 0.095 12.4 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DNA_pol_viral_N PF00242.12 CEH17671.1 - 0.085 11.8 6.1 0.11 11.5 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 CEH17671.1 - 1.1 7.5 9.5 1.3 7.1 6.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1180 PF06679.7 CEH17671.1 - 2.2 8.1 5.5 4.9 7.0 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) ADH_zinc_N_2 PF13602.1 CEH17673.1 - 1.7e-13 51.5 0.2 1.5e-12 48.5 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CEH17673.1 - 0.0003 20.3 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Rhomboid PF01694.17 CEH17674.1 - 5.5e-30 104.3 9.9 5.5e-30 104.3 6.8 1.8 2 0 0 2 2 2 1 Rhomboid family DUF457 PF04307.9 CEH17674.1 - 0.027 13.8 1.6 0.11 11.7 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF4448 PF14610.1 CEH17676.1 - 0.0017 17.9 0.2 0.0083 15.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Glycoamylase PF10091.4 CEH17676.1 - 0.29 10.1 3.3 1.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative glucoamylase SAPS PF04499.10 CEH17676.1 - 2.3 6.7 6.7 0.78 8.3 1.1 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.6 CEH17676.1 - 5.7 6.0 18.5 0.73 8.9 0.0 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.11 CEH17676.1 - 9.3 6.0 7.6 4.6 7.0 0.7 2.8 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Methyltransf_28 PF02636.12 CEH17677.1 - 1.1e-30 106.9 0.0 1.6e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 CEH17677.1 - 0.00013 21.1 0.0 0.00021 20.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 CEH17677.1 - 0.00094 19.6 0.1 0.0067 16.8 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain RRM_6 PF14259.1 CEH17678.1 - 2.4e-06 27.4 0.0 4.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEH17678.1 - 0.039 13.5 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 CEH17678.1 - 0.7 9.6 14.8 1.4 8.6 10.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DDE_Tnp_4 PF13359.1 CEH17679.1 - 1.2e-20 73.7 0.0 2.3e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease TFIIF_beta PF02270.10 CEH17679.1 - 0.018 14.8 0.4 0.027 14.2 0.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, beta subunit DSHCT PF08148.7 CEH17679.1 - 0.025 13.8 1.7 0.08 12.1 0.0 2.2 2 0 0 2 2 2 0 DSHCT (NUC185) domain TetR_N PF00440.18 CEH17679.1 - 0.07 12.7 0.6 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family ATP11 PF06644.6 CEH17680.1 - 0.28 10.6 5.2 2.3 7.6 3.7 1.9 2 0 0 2 2 2 0 ATP11 protein HSP70 PF00012.15 CEH17682.1 - 9.1e-199 661.2 12.0 4.8e-133 444.2 1.2 3.1 2 1 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 CEH17682.1 - 1.5e-10 40.2 0.2 0.00017 20.2 0.1 2.2 1 1 1 2 2 2 2 MreB/Mbl protein Abhydrolase_6 PF12697.2 CEH17682.1 - 0.0006 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH17682.1 - 0.00062 19.5 0.0 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH17682.1 - 0.00098 18.7 0.1 0.0084 15.6 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DDR PF08841.5 CEH17682.1 - 0.0034 16.2 1.4 0.022 13.5 0.4 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 CEH17682.1 - 0.013 15.1 0.0 0.036 13.6 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain PGAP1 PF07819.8 CEH17682.1 - 0.044 13.3 0.0 0.67 9.5 0.0 2.5 3 0 0 3 3 3 0 PGAP1-like protein Lipase_3 PF01764.20 CEH17682.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) zf-H2C2_2 PF13465.1 CEH17684.1 - 9.3e-22 76.1 20.2 8e-07 29.0 0.1 4.9 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 CEH17684.1 - 1.4e-18 66.0 29.4 4.4e-05 23.5 1.4 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH17684.1 - 4.7e-11 42.2 28.1 0.0094 16.2 1.8 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CEH17684.1 - 0.064 13.1 16.1 0.13 12.1 0.9 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEH17684.1 - 0.35 11.0 12.7 1.2 9.4 0.4 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 CEH17684.1 - 0.71 10.2 12.8 0.43 10.9 0.6 3.2 2 1 1 3 3 3 0 TRAF-type zinc finger zf-met PF12874.2 CEH17684.1 - 3.6 7.9 10.6 8.1 6.7 0.4 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 CEH17684.1 - 4.9 6.8 8.3 6.9 6.4 0.8 3.1 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger PTCB-BRCT PF12738.2 CEH17685.1 - 4.4e-14 52.0 0.0 5.6e-06 26.1 0.0 3.9 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 CEH17685.1 - 5.5e-10 39.2 0.0 5.8e-05 23.1 0.0 3.8 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain MANEC PF07502.9 CEH17685.1 - 0.058 13.3 0.6 0.16 11.9 0.4 1.7 1 0 0 1 1 1 0 MANEC domain HSF_DNA-bind PF00447.12 CEH17686.1 - 4.8e-36 123.0 0.1 1.2e-35 121.7 0.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 CEH17686.1 - 3.5e-24 84.9 1.0 1.1e-23 83.3 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain Ribosomal_S15 PF00312.17 CEH17686.1 - 0.037 13.7 0.1 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S15 GOLGA2L5 PF15070.1 CEH17686.1 - 0.082 11.3 7.3 0.13 10.7 5.0 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 PEP-utilisers_N PF05524.8 CEH17686.1 - 1.2 8.9 4.3 0.81 9.4 1.1 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal PI3_PI4_kinase PF00454.22 CEH17687.1 - 8.6e-45 153.0 0.0 1.5e-44 152.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 CEH17687.1 - 1.7e-12 47.3 0.0 4.2e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 CEH17687.1 - 1.3e-08 34.1 0.5 4.4e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 FATC domain FHA PF00498.21 CEH17688.1 - 2.6e-06 27.4 0.0 5.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain Gti1_Pac2 PF09729.4 CEH17690.1 - 4.3e-58 195.8 1.3 2.1e-57 193.6 0.2 2.3 2 1 0 2 2 2 1 Gti1/Pac2 family Peptidase_S8 PF00082.17 CEH17691.1 - 1.3e-45 155.7 11.1 1.9e-45 155.2 7.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CEH17691.1 - 2.1e-14 53.8 0.2 4e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ribosomal_L14e PF01929.12 CEH17692.1 - 4.8e-27 94.1 1.0 6.5e-27 93.6 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CEH17692.1 - 5.6e-07 29.0 0.3 9.6e-07 28.2 0.2 1.4 1 0 0 1 1 1 1 KOW motif Rib_5-P_isom_A PF06026.9 CEH17693.1 - 1.5e-54 183.8 0.0 1.9e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) SprB PF13573.1 CEH17693.1 - 0.13 11.9 1.8 0.4 10.3 1.2 1.9 1 0 0 1 1 1 0 SprB repeat XPG_I_2 PF12813.2 CEH17694.1 - 7.3e-08 32.1 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing DUF3146 PF11344.3 CEH17694.1 - 0.0034 16.7 0.0 0.0079 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3146) HSP70 PF00012.15 CEH17696.1 - 1.7e-258 858.5 14.6 1.9e-258 858.3 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CEH17696.1 - 1.8e-12 46.5 5.8 1.7e-10 40.0 1.9 2.6 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CEH17696.1 - 0.00099 18.9 10.4 0.029 14.2 0.1 4.0 4 1 0 4 4 4 2 Cell division protein FtsA LUC7 PF03194.10 CEH17696.1 - 1.4 8.3 8.3 2.6 7.5 5.7 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Seryl_tRNA_N PF02403.17 CEH17696.1 - 4.4 7.3 12.4 12 6.0 8.3 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Methyltransf_11 PF08241.7 CEH17699.1 - 9.9e-10 38.7 0.0 3.1e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH17699.1 - 1e-07 32.5 0.0 4.2e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH17699.1 - 4.6e-07 29.5 0.0 1.2e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH17699.1 - 6.2e-05 23.3 0.0 0.00018 21.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH17699.1 - 0.00011 22.6 0.0 0.00038 20.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH17699.1 - 0.0047 16.6 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH17699.1 - 0.011 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 CEH17699.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DnaB_bind PF10410.4 CEH17699.1 - 0.04 13.9 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase RDM PF11002.3 CEH17699.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RFPL defining motif (RDM) TPR_11 PF13414.1 CEH17700.1 - 2.5e-16 59.0 4.2 1.5e-10 40.5 0.4 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CEH17700.1 - 1.5e-10 40.1 2.6 0.00013 21.5 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEH17700.1 - 1.5e-08 33.8 1.6 0.00058 19.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEH17700.1 - 3e-06 27.7 6.3 0.0005 20.6 2.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CEH17700.1 - 0.00012 21.9 1.1 0.055 13.4 0.6 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEH17700.1 - 0.00032 20.9 1.3 0.023 15.0 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEH17700.1 - 0.00038 20.0 0.0 0.034 13.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEH17700.1 - 0.00047 20.5 8.4 0.014 15.9 0.3 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.2 CEH17700.1 - 0.006 16.4 1.1 0.15 11.8 0.8 2.1 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) BTAD PF03704.12 CEH17700.1 - 0.036 14.3 2.3 0.091 13.0 1.6 1.6 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 CEH17700.1 - 0.046 14.1 1.9 42 4.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CEH17700.1 - 0.049 13.4 1.1 0.21 11.4 0.2 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CEH17700.1 - 0.13 12.5 1.8 8.9 6.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 CEH17700.1 - 0.27 11.7 3.0 5.5 7.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Inositol_P PF00459.20 CEH17701.1 - 6.6e-52 176.4 0.0 4.6e-50 170.4 0.0 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family PX PF00787.19 CEH17702.1 - 1.3e-16 60.3 0.0 3.3e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 PX domain Zn_clus PF00172.13 CEH17703.1 - 1.1e-08 34.8 8.0 2e-08 34.0 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAR PF03114.13 CEH17704.1 - 1.2e-41 142.6 3.1 1.8e-41 142.1 2.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CEH17704.1 - 5.4e-15 54.5 0.0 1.1e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEH17704.1 - 1.5e-14 53.2 0.1 2.4e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEH17704.1 - 5.7e-11 41.7 0.1 9e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain FAM92 PF06730.6 CEH17704.1 - 0.00086 18.7 1.6 0.0012 18.2 0.8 1.5 1 1 0 1 1 1 1 FAM92 protein Vps5 PF09325.5 CEH17704.1 - 0.012 14.8 2.6 0.039 13.1 1.8 1.8 1 1 0 1 1 1 0 Vps5 C terminal like Med3 PF11593.3 CEH17704.1 - 0.028 13.6 2.4 0.053 12.7 1.7 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal BLYB PF05289.6 CEH17704.1 - 0.036 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein Na_H_antiporter PF03553.9 CEH17706.1 - 0.1 11.6 2.1 0.11 11.5 1.5 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter family Glycoprotein_B PF00606.13 CEH17706.1 - 0.34 8.8 2.1 0.37 8.7 1.4 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Folate_carrier PF01770.13 CEH17706.1 - 0.97 7.8 2.9 1 7.7 2.0 1.0 1 0 0 1 1 1 0 Reduced folate carrier BPD_transp_2 PF02653.11 CEH17706.1 - 1.2 8.0 7.1 1.3 7.9 4.9 1.0 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component SseC PF04888.7 CEH17706.1 - 9.6 5.4 7.7 11 5.2 5.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family IncA PF04156.9 CEH17707.1 - 7.6e-05 22.3 16.0 7.6e-05 22.3 11.1 14.2 3 3 10 13 13 13 6 IncA protein NMD3 PF04981.8 CEH17708.1 - 1.2e-75 253.7 2.0 2e-75 252.9 1.4 1.4 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 CEH17708.1 - 0.061 13.1 3.3 0.13 12.1 0.9 2.4 2 1 0 2 2 2 0 Double zinc ribbon DUF3675 PF12428.3 CEH17708.1 - 0.066 13.4 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Plus-3 PF03126.13 CEH17709.1 - 2.6e-09 37.0 0.3 3.4e-07 30.2 0.2 2.5 1 1 0 1 1 1 1 Plus-3 domain SAM_2 PF07647.12 CEH17710.1 - 7.6e-11 41.6 0.0 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CEH17710.1 - 1e-07 31.9 0.0 2.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 CEH17710.1 - 0.13 12.1 0.2 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 IGR protein motif Gtr1_RagA PF04670.7 CEH17712.1 - 4.9e-33 114.2 0.1 1.8e-11 43.6 0.0 3.2 3 0 0 3 3 3 3 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 CEH17712.1 - 0.00037 20.5 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 CEH17712.1 - 0.0024 17.7 0.0 0.005 16.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 CEH17712.1 - 0.0038 17.1 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arf PF00025.16 CEH17712.1 - 0.011 15.0 0.0 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF815 PF05673.8 CEH17712.1 - 0.08 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CEH17712.1 - 0.19 11.4 0.0 0.44 10.2 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase Sec63 PF02889.11 CEH17714.1 - 2.1e-38 132.3 0.0 4.2e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CEH17714.1 - 7e-17 61.4 0.4 2.5e-10 40.1 0.0 3.2 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH17714.1 - 1.8e-10 40.5 0.0 5e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH17714.1 - 0.00046 20.0 0.0 0.017 14.9 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit MarR PF01047.17 CEH17714.1 - 0.0068 16.0 0.0 0.024 14.3 0.0 2.0 1 0 0 1 1 1 1 MarR family AAA_19 PF13245.1 CEH17714.1 - 0.012 15.3 0.0 0.04 13.6 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CEH17714.1 - 0.027 14.0 0.2 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain HHH_5 PF14520.1 CEH17714.1 - 0.035 14.2 0.0 0.14 12.3 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain NTPase_1 PF03266.10 CEH17714.1 - 0.08 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 NTPase UvrD-helicase PF00580.16 CEH17714.1 - 0.092 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_23 PF13476.1 CEH17714.1 - 0.17 12.1 0.0 0.5 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain adh_short PF00106.20 CEH17715.1 - 5.4e-22 78.4 0.0 6.6e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH17715.1 - 4.7e-11 42.6 0.0 6.3e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CEH17715.1 - 7.2e-08 32.4 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CEH17715.1 - 1.1e-07 32.0 0.0 1.5e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CEH17715.1 - 2.6e-06 27.0 0.0 3.5e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CEH17715.1 - 1.9e-05 24.7 0.0 4.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CEH17715.1 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 CEH17715.1 - 0.0017 17.3 0.1 0.003 16.5 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 CEH17715.1 - 0.0041 16.0 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CEH17715.1 - 0.0089 15.3 0.1 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF4142 PF13628.1 CEH17715.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) 3HCDH_N PF02737.13 CEH17715.1 - 0.025 14.2 0.1 0.059 13.0 0.0 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 CEH17715.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF692 PF05114.8 CEH17715.1 - 0.075 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF692) Mastoparan_2 PF08251.6 CEH17715.1 - 2.9 8.1 4.4 0.57 10.3 0.3 2.0 2 0 0 2 2 1 0 Mastoparan peptide DNA_ligase_A_C PF04679.10 CEH17716.1 - 9.7e-08 32.3 0.0 2e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase C terminal region Acetyltransf_7 PF13508.1 CEH17717.1 - 9.9e-10 38.4 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CEH17717.1 - 2.5e-08 33.8 0.0 4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CEH17717.1 - 5e-06 26.6 0.0 6.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEH17717.1 - 0.00026 20.8 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEH17717.1 - 0.0004 20.0 0.0 0.0017 18.0 0.0 1.8 1 1 0 2 2 2 1 FR47-like protein Mec-17 PF05301.6 CEH17717.1 - 0.035 14.0 0.0 0.061 13.2 0.0 1.5 1 1 0 1 1 1 0 Touch receptor neuron protein Mec-17 TauD PF02668.11 CEH17718.1 - 2.1e-25 89.8 0.0 7.6e-24 84.7 0.0 2.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 CEH17718.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 CsiD AAA PF00004.24 CEH17719.1 - 0.0014 18.8 0.0 0.0034 17.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CEH17719.1 - 0.0069 16.1 1.6 0.15 11.8 0.0 3.5 3 0 0 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 CEH17719.1 - 0.0082 16.9 0.2 0.035 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CEH17719.1 - 0.015 15.4 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEH17719.1 - 0.027 14.4 0.1 0.027 14.4 0.0 3.5 4 1 0 4 4 4 0 AAA ATPase domain Rad17 PF03215.10 CEH17719.1 - 0.09 11.4 0.0 0.24 10.0 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 CEH17719.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 CEH17719.1 - 0.13 11.4 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Abhydrolase_3 PF07859.8 CEH17720.1 - 7.5e-27 94.2 0.0 1.3e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH17720.1 - 5.2e-07 29.5 0.0 8.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CEH17720.1 - 0.047 12.9 0.0 0.85 8.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2424 PF10340.4 CEH17720.1 - 0.24 10.0 0.0 0.36 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) F-box-like PF12937.2 CEH17721.1 - 0.00029 20.4 0.0 0.0013 18.4 0.0 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 CEH17721.1 - 0.033 13.8 2.4 1.9 8.2 1.7 2.9 1 1 0 1 1 1 0 F-box domain HORMA PF02301.13 CEH17723.1 - 1.8e-46 158.2 1.7 4.4e-46 156.9 0.0 2.1 2 0 0 2 2 2 1 HORMA domain PHD PF00628.24 CEH17723.1 - 3e-08 33.2 7.5 5.5e-08 32.3 5.2 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CEH17723.1 - 0.0016 17.7 3.5 0.003 16.8 2.5 1.4 1 0 0 1 1 1 1 PHD-finger Profilin PF00235.14 CEH17725.1 - 1.9e-40 137.7 0.0 2.1e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Profilin Sec10 PF07393.6 CEH17726.1 - 9.4e-97 324.9 0.0 4.9e-96 322.5 0.0 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 CEH17726.1 - 8.5e-06 25.4 0.0 1.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH17726.1 - 0.001 18.6 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain ADK PF00406.17 CEH17727.1 - 1.4e-37 128.8 0.0 1.7e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CEH17727.1 - 1.8e-13 49.8 0.0 3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 CEH17727.1 - 8.4e-07 29.3 0.0 1.4e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CEH17727.1 - 5e-06 27.3 0.0 9.3e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEH17727.1 - 0.0021 17.9 0.0 0.0051 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 CEH17727.1 - 0.12 11.9 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Mito_carr PF00153.22 CEH17728.1 - 5.6e-28 96.4 2.2 1.3e-15 56.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Zip PF02535.17 CEH17729.1 - 0.0054 15.7 0.0 0.0093 14.9 0.0 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Ctr PF04145.10 CEH17731.1 - 4.7e-33 114.2 0.1 1.6e-32 112.5 0.0 1.8 1 1 0 1 1 1 1 Ctr copper transporter family ABC_tran PF00005.22 CEH17732.1 - 2e-62 209.5 0.0 4.4e-31 108.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CEH17732.1 - 2.3e-62 210.9 21.1 1e-32 113.6 1.9 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CEH17732.1 - 3.2e-11 42.9 0.0 0.0045 16.2 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CEH17732.1 - 6.7e-10 39.2 1.8 0.00057 19.9 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CEH17732.1 - 6.9e-10 39.8 0.0 0.00011 23.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CEH17732.1 - 3.2e-09 37.0 0.2 0.0046 17.0 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CEH17732.1 - 5.8e-08 32.1 0.2 0.0073 15.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CEH17732.1 - 1.5e-07 31.6 0.0 1.8 8.4 0.0 4.2 4 0 0 4 4 4 1 AAA domain ABC_ATPase PF09818.4 CEH17732.1 - 6e-07 28.4 0.1 0.0054 15.3 0.0 2.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_18 PF13238.1 CEH17732.1 - 8e-07 29.4 0.0 0.028 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CEH17732.1 - 4.4e-06 26.5 0.9 0.25 11.3 0.1 3.8 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 CEH17732.1 - 5e-06 25.7 0.0 0.03 13.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 CEH17732.1 - 9e-06 25.3 0.0 0.26 10.7 0.0 3.9 4 0 0 4 4 4 1 AAA-like domain AAA_5 PF07728.9 CEH17732.1 - 1e-05 25.2 0.0 0.47 10.1 0.0 4.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CEH17732.1 - 3.8e-05 23.5 0.9 0.078 12.8 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 CEH17732.1 - 4.3e-05 23.0 0.0 0.14 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 CEH17732.1 - 7.5e-05 22.6 0.1 0.17 11.6 0.0 2.8 3 0 0 3 3 2 2 Domain of unknown function DUF87 RNA_helicase PF00910.17 CEH17732.1 - 0.00035 20.7 0.0 0.7 10.0 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ATP-synt_ab PF00006.20 CEH17732.1 - 0.00035 20.1 0.0 0.78 9.1 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.15 CEH17732.1 - 0.00038 20.1 0.0 0.16 11.6 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA PF00004.24 CEH17732.1 - 0.00091 19.4 0.0 11 6.2 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CEH17732.1 - 0.0013 18.3 0.2 0.62 9.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 CEH17732.1 - 0.0021 17.7 0.0 2 8.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 CEH17732.1 - 0.0022 17.1 0.0 1 8.3 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.13 CEH17732.1 - 0.0037 16.8 0.0 0.73 9.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 CEH17732.1 - 0.0073 16.0 0.0 3.1 7.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 CEH17732.1 - 0.0076 15.7 0.0 4.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 CEH17732.1 - 0.01 15.8 0.2 5.8 6.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain CbiA PF01656.18 CEH17732.1 - 0.011 15.1 0.1 6.3 6.1 0.0 2.7 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Miro PF08477.8 CEH17732.1 - 0.011 16.2 0.0 5.9 7.4 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 CEH17732.1 - 0.014 15.2 0.0 1 9.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CEH17732.1 - 0.02 14.3 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 CEH17732.1 - 0.03 13.7 0.2 7.4 5.9 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 CEH17732.1 - 0.03 14.3 0.0 10 6.1 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.18 CEH17732.1 - 0.035 14.0 0.0 24 4.9 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.12 CEH17732.1 - 0.038 13.3 0.0 7.5 5.8 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase NB-ARC PF00931.17 CEH17732.1 - 0.11 11.2 0.3 13 4.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.13 CEH17732.1 - 0.12 11.9 0.0 20 4.6 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.18 CEH17732.1 - 0.17 11.7 0.1 80 3.0 0.0 3.4 3 0 0 3 3 3 0 Dynamin family G-alpha PF00503.15 CEH17732.1 - 0.17 10.5 0.0 3.7 6.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit tRNA_lig_kinase PF08303.6 CEH17732.1 - 0.21 11.4 0.0 0.81 9.5 0.0 1.9 2 0 0 2 2 2 0 tRNA ligase kinase domain KaiC PF06745.8 CEH17732.1 - 0.27 10.3 0.1 21 4.1 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.1 CEH17732.1 - 0.29 11.4 0.0 11 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Cyclin_N PF00134.18 CEH17733.1 - 1.1e-08 34.6 0.0 2.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CEH17733.1 - 2.3e-06 28.1 1.7 2.3e-06 28.0 0.0 2.0 2 1 0 2 2 2 1 Cyclin CENP-H PF05837.7 CEH17735.1 - 4.2 7.5 5.4 8.4 6.6 0.5 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CorA PF01544.13 CEH17736.1 - 1.5e-07 30.7 1.7 2.3e-07 30.1 1.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein BTB PF00651.26 CEH17737.1 - 3.2e-11 43.1 0.0 2.3e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain CAP_GLY PF01302.20 CEH17737.1 - 6.1e-08 32.2 0.0 1.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain zf-Tim10_DDP PF02953.10 CEH17738.1 - 1.2e-08 34.1 1.8 2.1e-08 33.3 1.3 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FAD_binding_4 PF01565.18 CEH17739.1 - 5.6e-29 100.3 1.4 9.4e-29 99.6 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CEH17739.1 - 2.1e-10 40.3 0.0 5e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like IF4E PF01652.13 CEH17740.1 - 2.4e-45 154.0 0.0 3.8e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Abhydrolase_3 PF07859.8 CEH17741.1 - 1.1e-35 123.2 0.2 1.3e-35 122.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH17741.1 - 7.2e-07 29.0 0.1 1.1e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CEH17741.1 - 7.6e-05 22.0 0.0 0.08 12.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 CEH17741.1 - 0.00021 20.2 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.23 CEH17741.1 - 0.00086 18.1 0.1 0.0067 15.1 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 CEH17741.1 - 0.0057 15.8 0.2 0.069 12.3 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 CEH17741.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase PF07224.6 CEH17741.1 - 0.061 12.1 0.0 0.098 11.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Esterase_phd PF10503.4 CEH17741.1 - 0.079 12.1 0.0 0.33 10.1 0.0 2.0 3 0 0 3 3 3 0 Esterase PHB depolymerase Pro-kuma_activ PF09286.6 CEH17742.1 - 6.4e-34 117.0 0.0 1.3e-33 116.0 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CEH17742.1 - 6.9e-10 38.5 0.0 1.4e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 Subtilase family CBM_25 PF03423.8 CEH17742.1 - 0.16 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Sugar_tr PF00083.19 CEH17743.1 - 3.4e-121 404.9 27.3 3.8e-121 404.8 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CEH17743.1 - 4.2e-17 61.9 34.7 4.2e-17 61.9 24.1 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CEH17743.1 - 0.25 11.1 7.5 1.5 8.6 0.1 3.7 3 0 0 3 3 3 0 MFS_1 like family Abhydrolase_3 PF07859.8 CEH17744.1 - 5.8e-14 52.1 1.0 9.8e-14 51.4 0.5 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH17744.1 - 4.9e-13 49.0 0.4 7.3e-13 48.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH17744.1 - 2e-08 34.4 3.0 2.9e-08 33.8 2.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CEH17744.1 - 3.5e-06 26.0 1.3 8.7e-05 21.4 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.11 CEH17744.1 - 0.0058 16.0 0.0 3.1 7.1 0.0 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CEH17744.1 - 0.0067 15.6 0.3 0.21 10.7 0.1 2.7 2 1 0 2 2 2 1 Prolyl oligopeptidase family VirJ PF06057.6 CEH17744.1 - 0.061 13.1 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) CAP_GLY PF01302.20 CEH17744.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 CAP-Gly domain DUF2305 PF10230.4 CEH17744.1 - 0.083 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) KilA-N PF04383.8 CEH17745.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 KilA-N domain Ham1p_like PF01725.11 CEH17746.1 - 1e-49 168.4 0.0 1.2e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family CTDII PF01556.13 CEH17747.1 - 2.1e-26 91.6 0.0 5.6e-21 74.2 0.0 2.2 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CEH17747.1 - 2.3e-06 27.5 8.4 3.9e-06 26.8 5.8 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-NADH-PPase PF09297.6 CEH17747.1 - 2.4 7.7 6.3 0.85 9.1 0.6 2.8 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Pkinase PF00069.20 CEH17749.1 - 1.9e-26 92.7 0.0 5.2e-26 91.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17749.1 - 1.5e-10 40.5 0.0 2.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH17749.1 - 0.21 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ER_lumen_recept PF00810.13 CEH17750.1 - 6.6e-56 188.8 6.9 9.1e-56 188.4 4.8 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CEH17750.1 - 0.0091 15.5 6.8 2.5 7.6 0.3 4.2 3 1 1 4 4 4 2 PQ loop repeat CMS1 PF14617.1 CEH17751.1 - 3.2e-36 124.6 13.8 3.9e-21 75.2 0.1 2.8 1 1 2 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 CEH17751.1 - 0.059 12.8 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase DOR PF14839.1 CEH17751.1 - 2.1 8.0 8.6 2.6 7.7 0.2 2.4 2 0 0 2 2 2 0 DOR family ALO PF04030.9 CEH17752.1 - 8.1e-67 225.5 0.0 4.9e-58 196.7 0.0 2.3 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CEH17752.1 - 1.3e-15 57.0 0.0 3.4e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain DUF4098 PF13345.1 CEH17754.1 - 0.14 12.1 0.1 8.3 6.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4098) Myosin_head PF00063.16 CEH17755.1 - 1.5e-248 826.3 0.0 1.5e-248 826.3 0.0 3.1 3 1 1 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CEH17755.1 - 1.2e-14 53.0 68.3 1.2e-14 53.0 47.3 5.0 3 2 1 4 4 4 2 Myosin tail Myosin_N PF02736.14 CEH17755.1 - 0.00012 21.6 0.0 0.00026 20.5 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 CEH17755.1 - 0.0059 16.3 0.0 0.13 12.0 0.0 3.4 2 0 0 2 2 2 1 Part of AAA domain HCNGP PF07818.8 CEH17756.1 - 4.4e-15 55.4 0.0 7.8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein Sod_Fe_C PF02777.13 CEH17757.1 - 3.3e-38 129.7 0.1 6.2e-38 128.8 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CEH17757.1 - 1.7e-33 114.6 3.5 4.2e-33 113.4 2.4 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Abhydrolase_6 PF12697.2 CEH17758.1 - 0.0031 17.4 0.1 0.0045 16.9 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH17758.1 - 0.0051 16.5 0.0 0.02 14.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family SMC_Nse1 PF07574.8 CEH17759.1 - 3.1e-22 79.1 0.0 8.2e-14 51.6 0.0 2.2 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CEH17759.1 - 4.4e-07 29.7 7.2 2.6e-06 27.3 5.0 2.1 1 1 0 1 1 1 1 RING-like domain zf-HC5HC2H PF13771.1 CEH17759.1 - 0.081 13.0 2.3 0.21 11.7 1.6 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain OrfB_Zn_ribbon PF07282.6 CEH17759.1 - 0.53 9.9 0.0 0.53 9.9 0.0 2.6 2 1 1 3 3 3 0 Putative transposase DNA-binding domain C1_1 PF00130.17 CEH17759.1 - 0.83 9.4 5.9 0.29 10.8 1.1 2.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 CEH17759.1 - 3 7.7 7.2 52 3.7 3.4 3.1 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.1 CEH17759.1 - 3.3 7.2 5.7 15 5.1 0.3 3.0 3 0 0 3 3 3 0 Transposase zinc-binding domain HTH_31 PF13560.1 CEH17760.1 - 0.0097 16.0 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Cnl2_NKP2 PF09447.5 CEH17761.1 - 0.033 13.8 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Ribosomal_S19 PF00203.16 CEH17762.1 - 4.2e-31 106.4 0.3 6.6e-31 105.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 CEH17762.1 - 0.0062 16.4 0.0 0.0075 16.1 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH SKI PF01202.17 CEH17763.1 - 8.7e-27 93.9 0.0 1.6e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase DHquinase_I PF01487.10 CEH17763.1 - 3.3e-14 53.0 0.0 9.4e-09 35.2 0.0 2.5 1 1 1 2 2 2 2 Type I 3-dehydroquinase AAA PF00004.24 CEH17763.1 - 0.074 13.2 0.1 0.23 11.6 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEH17763.1 - 0.2 12.4 0.0 0.38 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MbeD_MobD PF04899.7 CEH17764.1 - 0.075 12.9 1.1 0.45 10.4 0.0 2.4 2 0 0 2 2 2 0 MbeD/MobD like G-alpha PF00503.15 CEH17765.1 - 4.2e-104 348.3 0.0 7.8e-104 347.4 0.0 1.4 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.16 CEH17765.1 - 1.2e-12 47.4 0.2 6.7e-08 31.9 0.0 2.9 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 CEH17765.1 - 0.0013 18.9 0.0 0.0033 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Myosin_head PF00063.16 CEH17765.1 - 0.013 13.5 0.1 0.021 12.9 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) ABC_tran PF00005.22 CEH17765.1 - 0.014 15.6 0.4 0.084 13.1 0.0 2.2 1 1 1 2 2 2 0 ABC transporter AAA_24 PF13479.1 CEH17765.1 - 0.053 13.1 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CEH17765.1 - 0.059 12.5 0.0 0.18 10.9 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CEH17765.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 CEH17765.1 - 0.075 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 CEH17765.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Thaumatin PF00314.12 CEH17767.1 - 3.9e-12 46.0 1.2 7.5e-12 45.1 0.2 1.7 1 1 1 2 2 2 2 Thaumatin family Pribosyltran PF00156.22 CEH17768.1 - 1.7e-15 56.8 0.2 2.4e-15 56.3 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CEH17768.1 - 0.0025 17.0 0.0 0.0032 16.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase NMO PF03060.10 CEH17771.1 - 5.5e-54 183.5 0.4 9.6e-54 182.7 0.3 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CEH17771.1 - 1.8e-06 27.0 0.5 0.0052 15.7 0.7 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CEH17771.1 - 0.00076 18.4 0.2 0.0013 17.6 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1902 PF08972.6 CEH17771.1 - 0.0013 18.2 0.2 0.2 11.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1902) TMP-TENI PF02581.12 CEH17771.1 - 0.056 12.5 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 CEH17771.1 - 0.058 12.6 0.2 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein CCT_2 PF09425.5 CEH17772.1 - 5.1 6.7 5.5 0.76 9.3 0.9 1.8 2 0 0 2 2 2 0 Divergent CCT motif Acyltransferase PF01553.16 CEH17773.1 - 3.2e-11 42.7 0.0 0.00018 20.9 0.0 2.6 2 0 0 2 2 2 2 Acyltransferase CTP-dep_RFKase PF01982.11 CEH17773.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF120 ASF1_hist_chap PF04729.8 CEH17774.1 - 6.7e-64 214.1 0.1 7.9e-64 213.9 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Kinesin PF00225.18 CEH17775.1 - 5.4e-110 367.2 0.3 7.4e-110 366.7 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 CEH17775.1 - 6.2e-34 116.6 0.0 1.4e-33 115.4 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 CEH17775.1 - 5.4e-12 45.8 0.0 1.7e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 CEH17775.1 - 6e-08 32.5 0.1 1.3e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 CEH17775.1 - 1.4e-06 28.2 0.0 7.5e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.1 CEH17775.1 - 0.039 14.2 0.1 0.4 10.9 0.1 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain Peroxin-3 PF04882.7 CEH17776.1 - 5.4e-100 335.1 0.0 9.5e-99 331.0 0.0 2.0 1 1 0 1 1 1 1 Peroxin-3 BTG PF07742.7 CEH17777.1 - 1.3e-15 56.8 0.0 2.2e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 BTG family Septin PF00735.13 CEH17779.1 - 3e-123 410.3 0.1 5.1e-123 409.5 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CEH17779.1 - 2.1e-07 30.9 0.0 5.1e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CEH17779.1 - 4.1e-06 26.0 0.0 1.1e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CEH17779.1 - 6e-05 22.9 1.4 0.018 14.8 0.0 2.9 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 CEH17779.1 - 0.00026 20.4 0.1 0.0092 15.4 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CEH17779.1 - 0.0012 18.9 0.0 0.007 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CEH17779.1 - 0.0015 18.0 0.0 0.0022 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain Ras PF00071.17 CEH17779.1 - 0.0017 17.7 0.0 0.015 14.7 0.0 2.4 2 0 0 2 2 2 1 Ras family Arch_ATPase PF01637.13 CEH17779.1 - 0.0025 17.5 0.6 1 8.9 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase AIG1 PF04548.11 CEH17779.1 - 0.0039 16.3 0.3 0.013 14.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 CEH17779.1 - 0.0067 16.9 0.0 0.099 13.1 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 CEH17779.1 - 0.01 16.1 7.1 0.018 15.3 0.4 2.8 1 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 CEH17779.1 - 0.021 14.8 0.1 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 CEH17779.1 - 0.022 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 CEH17779.1 - 0.068 12.8 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 CEH17779.1 - 0.07 12.6 0.5 6.3 6.2 0.0 3.0 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.10 CEH17779.1 - 0.24 10.5 6.4 0.22 10.6 3.7 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit YlqD PF11068.3 CEH17779.1 - 0.46 10.5 7.0 0.92 9.5 4.9 1.5 1 0 0 1 1 1 0 YlqD protein IncA PF04156.9 CEH17779.1 - 2.4 7.7 8.1 4.1 6.9 5.6 1.3 1 0 0 1 1 1 0 IncA protein ABC_tran PF00005.22 CEH17780.1 - 6.4e-47 159.3 0.0 3.8e-28 98.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CEH17780.1 - 1.9e-31 109.4 13.3 7.6e-20 71.4 1.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 CEH17780.1 - 1.3e-09 38.4 0.0 0.016 15.1 0.0 3.8 2 2 0 4 4 4 2 AAA domain SMC_N PF02463.14 CEH17780.1 - 3.6e-08 32.9 0.7 0.11 11.6 0.1 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CEH17780.1 - 6.2e-08 32.0 1.6 0.0093 15.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CEH17780.1 - 1.2e-05 25.4 0.1 0.00049 20.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEH17780.1 - 6.7e-05 22.9 5.9 7.7e-05 22.7 1.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 CEH17780.1 - 8.3e-05 22.5 0.0 0.15 12.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 CEH17780.1 - 8.4e-05 23.0 0.0 0.25 11.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 CEH17780.1 - 8.7e-05 22.0 0.3 0.26 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CEH17780.1 - 0.00011 21.7 0.5 0.67 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain FtsK_SpoIIIE PF01580.13 CEH17780.1 - 0.00045 19.7 0.2 0.084 12.3 0.0 2.8 3 0 0 3 3 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 CEH17780.1 - 0.00054 19.8 0.2 0.23 11.2 0.0 2.5 2 0 0 2 2 2 1 Dynamin family T2SE PF00437.15 CEH17780.1 - 0.0023 16.8 0.1 1.1 8.1 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 CEH17780.1 - 0.003 17.2 0.1 0.16 11.6 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CEH17780.1 - 0.0038 18.0 0.0 0.12 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 CEH17780.1 - 0.0067 15.5 0.0 0.54 9.2 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 CEH17780.1 - 0.0095 15.1 0.3 0.36 9.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 CEH17780.1 - 0.013 15.3 0.3 4.4 7.1 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CEH17780.1 - 0.019 14.5 0.3 0.13 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CEH17780.1 - 0.026 14.8 0.2 9 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CEH17780.1 - 0.037 13.7 0.1 0.69 9.6 0.0 2.8 3 0 0 3 3 3 0 NTPase ABC_ATPase PF09818.4 CEH17780.1 - 0.039 12.5 0.6 1.2 7.6 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_14 PF13173.1 CEH17780.1 - 0.046 13.6 0.0 12 5.8 0.0 3.4 4 0 0 4 4 4 0 AAA domain SbcCD_C PF13558.1 CEH17780.1 - 0.047 13.5 2.8 0.3 11.0 0.2 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Pox_A32 PF04665.7 CEH17780.1 - 0.15 11.3 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein DUF87 PF01935.12 CEH17780.1 - 0.19 11.5 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 CEH17780.1 - 0.29 10.7 0.2 18 4.9 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 CEH17780.1 - 0.3 11.4 0.2 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 CEH17780.1 - 0.37 9.7 0.3 4 6.3 0.0 2.3 3 0 0 3 3 2 0 Septin NB-ARC PF00931.17 CEH17780.1 - 0.43 9.3 0.2 3.8 6.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Skp1 PF01466.14 CEH17781.1 - 2.1e-40 136.5 1.3 2.1e-40 136.5 0.9 1.5 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CEH17781.1 - 2e-21 75.8 0.2 5.1e-21 74.5 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 CEH17781.1 - 0.0066 16.4 0.1 0.099 12.6 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain RhoGEF PF00621.15 CEH17782.1 - 5.7e-36 124.0 0.1 5.7e-36 124.0 0.1 1.6 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.23 CEH17782.1 - 7.4e-17 60.4 0.9 7.1e-08 31.7 0.1 2.6 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.2 CEH17782.1 - 1.3e-15 57.0 0.0 3.6e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_9 PF14604.1 CEH17782.1 - 2.1e-14 52.8 1.0 4.4e-07 29.3 0.1 2.8 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 CEH17782.1 - 1.5e-08 33.9 0.6 3.7e-08 32.7 0.4 1.7 1 0 0 1 1 1 1 WH2 motif SH3_2 PF07653.12 CEH17782.1 - 5.7e-07 28.9 0.0 0.0038 16.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain DUF1720 PF08226.6 CEH17782.1 - 0.00098 19.1 33.1 0.00098 19.1 23.0 6.6 4 1 3 7 7 7 1 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 CEH17782.1 - 0.0035 17.4 0.1 0.0098 16.0 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair PH PF00169.24 CEH17782.1 - 0.14 12.3 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 PH domain HTH_9 PF08221.6 CEH17784.1 - 4.7e-16 58.4 6.3 3.8e-08 33.0 0.0 4.4 5 0 0 5 5 5 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 CEH17784.1 - 6.7e-11 42.2 0.0 2.2e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 CEH17784.1 - 8.1e-08 31.7 1.6 3.9e-07 29.5 0.2 2.9 4 0 0 4 4 4 1 TFIIE alpha subunit DUF3582 PF12122.3 CEH17784.1 - 0.073 13.0 0.8 0.48 10.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3582) ERG4_ERG24 PF01222.12 CEH17785.1 - 3.3e-143 477.3 6.6 3.7e-143 477.1 4.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CEH17785.1 - 0.00013 21.3 0.1 0.00026 20.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CEH17785.1 - 0.0015 18.5 0.0 0.0015 18.5 0.0 2.8 4 0 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.9 CEH17785.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Med17 PF10156.4 CEH17786.1 - 2.8e-05 22.6 0.0 2.8e-05 22.6 0.0 2.8 3 1 0 3 3 3 1 Subunit 17 of Mediator complex FAM110_C PF14160.1 CEH17786.1 - 0.021 15.7 4.7 0.44 11.5 0.3 3.4 2 0 0 2 2 2 0 Centrosome-associated C terminus Pox_I6 PF04595.8 CEH17786.1 - 0.29 9.8 0.0 0.59 8.8 0.0 1.5 1 1 0 1 1 1 0 Poxvirus I6-like family Hist_deacetyl PF00850.14 CEH17787.1 - 6.3e-81 272.0 0.0 9.7e-81 271.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain CDC45 PF02724.9 CEH17787.1 - 0.33 8.9 5.3 0.45 8.4 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Actin PF00022.14 CEH17788.1 - 2.8e-157 523.2 0.0 3.4e-157 522.9 0.0 1.0 1 0 0 1 1 1 1 Actin Methyltransf_29 PF03141.11 CEH17788.1 - 0.0037 15.6 0.0 0.0054 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase ESSS PF10183.4 CEH17788.1 - 0.089 13.2 0.0 0.23 11.8 0.0 1.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) eIF3g PF12353.3 CEH17789.1 - 0.034 14.0 1.7 0.051 13.4 1.1 1.7 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF572 PF04502.8 CEH17789.1 - 0.18 10.9 9.8 0.22 10.6 6.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Bud13 PF09736.4 CEH17790.1 - 1.4e-32 112.9 1.2 1.6e-32 112.7 0.8 1.0 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex HAT PF02184.11 CEH17791.1 - 5.8e-16 57.9 59.2 3.7e-08 32.9 1.1 13.6 14 1 0 14 14 14 3 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 CEH17791.1 - 2.7e-14 52.3 35.7 6.1e-05 23.3 0.2 12.0 5 2 8 13 13 12 5 Tetratricopeptide repeat TPR_19 PF14559.1 CEH17791.1 - 4.1e-13 49.4 3.3 6e-06 26.5 0.0 6.4 4 1 2 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CEH17791.1 - 9.8e-09 35.6 8.8 6.4e-06 26.7 0.2 8.2 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 CEH17791.1 - 1.5e-08 34.1 9.0 0.013 15.0 0.0 5.3 6 1 0 6 6 5 3 TPR repeat TPR_2 PF07719.12 CEH17791.1 - 2.5e-08 33.2 5.0 0.019 14.8 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 CEH17791.1 - 4.5e-06 26.0 0.0 1.6 8.6 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 CEH17791.1 - 4.6e-05 22.6 21.9 0.088 11.8 3.4 5.4 2 2 4 6 6 6 4 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CEH17791.1 - 0.0001 22.0 12.5 0.15 11.8 0.1 6.5 5 2 0 5 5 5 1 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 CEH17791.1 - 0.00061 19.3 8.6 0.98 9.3 0.0 7.0 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 CEH17791.1 - 0.017 14.7 0.1 8.1 6.2 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEH17791.1 - 0.03 14.1 0.0 8.2 6.4 0.0 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 CEH17791.1 - 0.04 14.1 0.2 23 5.5 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat LCM PF04072.9 CEH17792.1 - 1.3e-19 70.5 0.0 2.1e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PMT PF02366.13 CEH17793.1 - 2.7e-74 249.6 13.8 2.7e-74 249.6 9.6 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CEH17793.1 - 4.1e-40 137.3 0.1 7.2e-31 107.2 0.0 2.2 2 0 0 2 2 2 2 MIR domain DUF1240 PF06836.7 CEH17793.1 - 1.7 8.9 3.9 32 4.8 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) Mito_carr PF00153.22 CEH17794.1 - 6.1e-49 163.6 1.2 8.7e-17 60.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2258 PF10015.4 CEH17795.1 - 0.05 13.4 0.1 0.072 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Utp21 PF04192.7 CEH17796.1 - 4.7e-19 68.4 0.1 8.4e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CEH17796.1 - 1.7e-18 65.7 4.8 0.00014 21.6 0.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF2454 PF10521.4 CEH17796.1 - 2.6e-06 26.6 0.0 2.8e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) Cytochrom_D1 PF02239.11 CEH17796.1 - 0.25 9.5 0.1 0.44 8.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain SBP56 PF05694.6 CEH17796.1 - 0.47 8.8 0.0 0.78 8.1 0.0 1.2 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) Sugar_tr PF00083.19 CEH17798.1 - 3.5e-05 22.5 15.0 0.013 14.0 6.2 3.7 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEH17798.1 - 0.00029 19.6 35.8 0.0052 15.5 14.5 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Carb_kinase PF01256.12 CEH17799.1 - 2.7e-42 144.7 0.0 4.4e-29 101.4 0.0 2.0 1 1 1 2 2 2 2 Carbohydrate kinase HK PF02110.10 CEH17799.1 - 0.14 11.3 0.0 3.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family RIC1 PF07064.8 CEH17800.1 - 6.6e-32 110.9 0.1 4e-31 108.4 0.1 2.0 1 1 0 1 1 1 1 RIC1 TFIIIC_sub6 PF10419.4 CEH17801.1 - 4.1e-13 48.5 0.1 6.3e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 TFIIIC subunit Daxx PF03344.10 CEH17801.1 - 0.0041 15.6 3.2 0.0044 15.5 2.2 1.1 1 0 0 1 1 1 1 Daxx Family WD40 PF00400.27 CEH17802.1 - 4.7e-50 165.7 9.2 7.7e-08 31.9 0.1 11.2 10 1 1 11 11 11 8 WD domain, G-beta repeat CTP_transf_2 PF01467.21 CEH17802.1 - 2.1e-06 27.8 0.0 5.7e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Cytidylyltransferase MFS_1 PF07690.11 CEH17803.1 - 4.5e-13 48.6 23.0 4.5e-13 48.6 15.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Bestrophin PF01062.16 CEH17803.1 - 0.066 12.1 0.0 0.066 12.1 0.0 1.7 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel UCH PF00443.24 CEH17804.1 - 1.4e-50 171.8 0.0 1.9e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEH17804.1 - 1.1e-26 94.0 0.0 2.1e-26 93.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CEH17804.1 - 0.014 14.6 0.1 7.2 5.7 0.1 3.3 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-AD PF07776.10 CEH17804.1 - 0.13 12.2 0.2 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) ING PF12998.2 CEH17805.1 - 6.1e-13 48.9 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CEH17805.1 - 4.7e-07 29.4 5.2 7.2e-07 28.8 3.6 1.3 1 0 0 1 1 1 1 PHD-finger Serglycin PF04360.7 CEH17805.1 - 0.0014 18.4 0.4 0.0014 18.4 0.3 1.9 2 0 0 2 2 2 1 Serglycin Ribosomal_60s PF00428.14 CEH17805.1 - 0.81 10.1 20.3 0.25 11.7 5.2 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein RNA_pol_A_bac PF01000.21 CEH17806.1 - 6.3e-26 90.7 0.0 1.8e-25 89.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CEH17806.1 - 1.5e-16 59.2 0.0 2.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-H2C2_2 PF13465.1 CEH17807.1 - 0.0088 16.2 0.9 0.11 12.8 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2HC_2 PF13913.1 CEH17807.1 - 0.026 14.1 2.4 0.053 13.1 1.7 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DUF3488 PF11992.3 CEH17812.1 - 0.11 11.0 0.3 0.16 10.5 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) NblA PF04485.7 CEH17816.1 - 0.023 14.5 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA zf-LYAR PF08790.6 CEH17817.1 - 0.079 12.6 0.3 0.18 11.4 0.2 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Clathrin PF00637.15 CEH17819.1 - 7.4e-13 48.3 0.2 0.00022 20.8 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.3 CEH17819.1 - 8e-09 35.2 0.3 1.6e-08 34.2 0.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 CEH17819.1 - 0.022 14.4 6.8 0.042 13.5 4.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain TPR_2 PF07719.12 CEH17819.1 - 0.029 14.2 0.3 0.71 9.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 CEH17819.1 - 0.14 11.9 7.3 0.31 10.8 5.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CEH17819.1 - 0.68 10.0 6.6 1.3 9.1 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH17819.1 - 3.7 7.2 5.8 7.3 6.3 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CEH17819.1 - 5.5 7.1 6.8 12 6.1 4.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger DUF3725 PF12523.3 CEH17820.1 - 0.00057 19.9 0.2 0.0086 16.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3725) zf-C2H2_4 PF13894.1 CEH17820.1 - 0.093 13.1 4.5 4.2 7.9 0.1 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger GFA PF04828.9 CEH17820.1 - 0.13 12.2 1.4 0.87 9.5 0.8 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF3085 PF11284.3 CEH17822.1 - 0.044 13.9 0.1 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) Toxin_57 PF15535.1 CEH17825.1 - 0.036 14.1 0.1 0.045 13.8 0.1 1.1 1 0 0 1 1 1 0 Putative toxin 57 Nop14 PF04147.7 CEH17826.1 - 0.73 7.6 25.2 1 7.1 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family NAD_kinase PF01513.16 CEH17827.1 - 8.5e-18 64.1 0.0 1.9e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase NAD_kinase PF01513.16 CEH17828.1 - 3.2e-41 141.0 0.0 5.5e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DUF4638 PF15472.1 CEH17828.1 - 2.2 7.7 8.0 5.2 6.5 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) RRM_1 PF00076.17 CEH17829.1 - 1.4e-06 27.8 0.0 2.9e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH17829.1 - 7.3e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CEH17829.1 - 0.00023 20.7 2.5 0.00023 20.7 1.8 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.16 CEH17829.1 - 0.01 15.6 0.3 0.01 15.6 0.2 2.0 3 0 0 3 3 3 0 FYVE zinc finger zf-CCCH_2 PF14608.1 CEH17829.1 - 0.025 14.5 4.0 0.032 14.2 1.8 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type RRM_5 PF13893.1 CEH17829.1 - 0.031 14.1 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arm PF00514.18 CEH17832.1 - 0.048 13.4 8.0 1.2 9.0 0.1 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ric8 PF10165.4 CEH17832.1 - 0.4 9.4 0.0 0.4 9.4 0.0 2.5 3 0 0 3 3 3 0 Guanine nucleotide exchange factor synembryn zf-rbx1 PF12678.2 CEH17833.1 - 5.1e-11 42.5 3.8 8.5e-11 41.8 2.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CEH17833.1 - 2.3e-10 40.1 8.7 6.1e-10 38.7 6.1 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CEH17833.1 - 7e-07 28.7 5.7 1.2e-06 28.1 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CEH17833.1 - 7.1e-06 25.7 1.3 1.3e-05 24.8 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CEH17833.1 - 1.4e-05 24.6 7.2 2.9e-05 23.6 5.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH17833.1 - 2e-05 24.5 1.7 2e-05 24.5 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH17833.1 - 6.5e-05 22.5 5.7 0.00012 21.7 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CEH17833.1 - 0.0098 15.7 1.3 0.024 14.5 0.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CEH17833.1 - 0.023 14.4 1.2 0.062 13.0 0.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 CEH17833.1 - 0.037 13.5 0.4 0.075 12.5 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 CEH17833.1 - 0.076 12.6 0.3 0.17 11.4 0.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4037 PF13228.1 CEH17833.1 - 0.38 11.0 0.0 5.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) FANCL_C PF11793.3 CEH17833.1 - 4.5 7.3 5.6 13 5.8 3.9 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 CEH17833.1 - 7.5 6.6 7.9 25 4.9 5.5 1.9 1 1 0 1 1 1 0 RING-variant domain Aldedh PF00171.17 CEH17834.1 - 5.6e-126 420.5 0.0 6.7e-126 420.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CEH17834.1 - 0.00093 18.0 0.0 0.0024 16.6 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) NAD_binding_6 PF08030.7 CEH17837.1 - 4.7e-17 62.3 0.0 8.6e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CEH17837.1 - 4.6e-16 58.6 0.0 6.4e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 CEH17837.1 - 7.4e-16 58.3 12.4 7.4e-16 58.3 8.6 2.6 4 0 0 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 CEH17837.1 - 0.00014 22.3 0.0 0.05 14.1 0.0 2.5 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain WD40 PF00400.27 CEH17839.1 - 7.3e-64 209.5 17.3 6.2e-13 48.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CEH17839.1 - 7.3e-09 34.2 7.8 0.022 12.8 0.1 5.4 1 1 3 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CEH17839.1 - 1.5e-07 31.3 0.0 0.0062 16.2 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CEH17839.1 - 0.063 12.3 2.7 2.5 7.1 0.1 2.9 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 CEH17839.1 - 0.071 10.9 0.3 0.48 8.1 0.1 2.1 2 0 0 2 2 2 0 IKI3 family DUF3312 PF11768.3 CEH17839.1 - 0.073 11.2 0.0 0.13 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Kelch_6 PF13964.1 CEH17839.1 - 0.096 12.9 0.1 5.2 7.4 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Molybdopterin PF00384.17 CEH17840.1 - 2.1e-66 224.4 0.0 1.3e-65 221.8 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 CEH17840.1 - 1.7e-17 62.3 0.0 3.9e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 CEH17840.1 - 2.6e-17 62.4 0.2 9.8e-17 60.5 0.1 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 CEH17840.1 - 6.3e-15 55.0 0.1 1.8e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 CEH17840.1 - 2.9e-07 30.1 1.2 2.9e-07 30.1 0.8 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 CEH17840.1 - 0.00046 19.9 0.1 0.03 14.0 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 CEH17840.1 - 0.16 11.6 1.3 4.1 7.1 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.18 CEH17841.1 - 1.9e-66 223.9 0.0 1.9e-66 223.9 0.0 2.3 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEH17841.1 - 6e-15 54.8 0.0 2e-14 53.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH17841.1 - 2.4e-08 34.0 0.1 4.8e-07 29.7 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CEH17841.1 - 0.00011 21.0 0.0 0.00011 21.0 0.0 2.5 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CEH17841.1 - 0.0036 16.8 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.1 CEH17841.1 - 0.0038 17.2 1.9 0.0038 17.2 1.3 2.9 3 1 0 3 3 3 1 DNA-binding domain AhpC-TSA_2 PF13911.1 CEH17842.1 - 4.3e-07 29.8 0.0 6.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme HAD PF12710.2 CEH17842.1 - 0.12 12.5 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SSF PF00474.12 CEH17844.1 - 4.1e-19 68.5 22.8 7.3e-19 67.6 15.8 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family WTF PF03303.8 CEH17844.1 - 0.046 13.1 0.1 0.13 11.6 0.1 1.7 1 0 0 1 1 1 0 WTF protein DUF912 PF06024.7 CEH17844.1 - 0.18 11.9 2.0 0.96 9.5 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ETRAMP PF09716.5 CEH17844.1 - 0.27 11.1 8.3 5.3 7.0 0.0 4.0 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Zn_clus PF00172.13 CEH17845.1 - 6.5e-08 32.3 6.7 2.1e-07 30.7 4.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF694 PF05107.7 CEH17845.1 - 0.076 12.2 0.2 0.42 9.8 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF694) MaoC_dehydratas PF01575.14 CEH17846.1 - 5.5e-26 90.3 0.0 1.2e-25 89.2 0.0 1.6 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CEH17846.1 - 4.3e-07 29.7 0.0 6.7e-06 25.9 0.0 2.4 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Rad21_Rec8_N PF04825.8 CEH17847.1 - 7.3e-26 90.2 0.0 1.3e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CEH17847.1 - 5.7e-12 44.6 0.0 1.3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CEH17847.1 - 0.00087 18.9 0.2 0.0021 17.7 0.0 1.6 2 0 0 2 2 2 1 ScpA/B protein DMP1 PF07263.6 CEH17847.1 - 0.058 12.1 2.1 0.041 12.6 0.2 1.6 2 0 0 2 2 2 0 Dentin matrix protein 1 (DMP1) Dynamitin PF04912.9 CEH17848.1 - 8.8e-29 100.4 1.0 7.5e-28 97.4 0.1 2.5 2 1 0 2 2 2 1 Dynamitin V-ATPase_G PF03179.10 CEH17848.1 - 1 9.6 5.0 3.6 7.9 2.0 2.3 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Herpes_BLRF2 PF05812.7 CEH17848.1 - 2.7 7.8 7.1 0.43 10.3 0.8 2.5 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein Pex14_N PF04695.8 CEH17849.1 - 2.4 8.2 20.6 17 5.4 11.2 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4614 PF15391.1 CEH17849.1 - 2.7 7.7 21.8 4.7 6.9 15.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF3827 PF12877.2 CEH17849.1 - 3.2 5.7 10.1 5.3 5.0 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Macoilin PF09726.4 CEH17849.1 - 3.3 5.8 11.5 0.031 12.5 2.8 1.4 2 0 0 2 2 2 0 Transmembrane protein Lin-8 PF03353.10 CEH17849.1 - 7.1 5.8 7.2 10 5.2 5.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Polysacc_deac_1 PF01522.16 CEH17850.1 - 4.2e-25 87.7 0.0 7.5e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEH17850.1 - 0.093 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 ThuA PF06283.6 CEH17851.1 - 4.4e-42 144.2 0.0 5.3e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation NAD_binding_1 PF00175.16 CEH17854.1 - 3.5e-26 91.8 0.0 5.8e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CEH17854.1 - 9.4e-17 60.9 0.0 1.7e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CEH17854.1 - 7.4e-06 25.9 0.0 0.00097 19.0 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CEH17854.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain PUF PF00806.14 CEH17860.1 - 1.6e-49 162.6 0.5 6e-08 31.7 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Glyco_hydro_47 PF01532.15 CEH17862.1 - 1.6e-146 488.5 0.0 1.9e-146 488.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_43 PF04616.9 CEH17863.1 - 6.7e-14 51.6 2.1 6.7e-14 51.6 1.5 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 43 Ssl1 PF04056.9 CEH17864.1 - 6.1e-67 224.9 0.0 1.4e-66 223.8 0.0 1.5 1 0 0 1 1 1 1 Ssl1-like Nup160 PF11715.3 CEH17864.1 - 1.7e-29 102.3 1.0 4.1e-29 101.1 0.7 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 VWA_2 PF13519.1 CEH17864.1 - 8.5e-11 42.2 0.1 7.5e-10 39.1 0.0 2.8 4 0 0 4 4 4 1 von Willebrand factor type A domain VWA PF00092.23 CEH17864.1 - 0.26 10.9 0.0 0.58 9.8 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain GST_C PF00043.20 CEH17865.1 - 1.2e-07 31.6 0.0 2.2e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEH17865.1 - 1.4e-07 31.3 0.3 5.6e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEH17865.1 - 1.4e-06 28.7 0.0 2.6e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CEH17865.1 - 9.2e-06 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Afi1 PF07792.7 CEH17866.1 - 4.8e-39 133.6 0.0 7.6e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 CEH17866.1 - 1.3e-30 105.3 0.0 2.1e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CEH17866.1 - 1.3e-05 23.9 0.0 0.013 13.9 0.0 2.3 2 0 0 2 2 2 2 Transport protein Avl9 Arrestin_N PF00339.24 CEH17867.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DRIM PF07539.7 CEH17868.1 - 1.8e-39 134.3 0.0 1.7e-38 131.2 0.0 2.7 2 0 0 2 2 2 1 Down-regulated in metastasis DUF3385 PF11865.3 CEH17868.1 - 0.46 10.4 4.1 15 5.5 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) HEAT PF02985.17 CEH17868.1 - 2.6 8.3 14.9 2.7 8.3 0.2 6.4 7 0 0 7 7 7 0 HEAT repeat PBP PF01161.15 CEH17873.1 - 9.8e-07 28.7 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SHOCT PF09851.4 CEH17873.1 - 0.12 11.9 0.1 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Short C-terminal domain Arf PF00025.16 CEH17874.1 - 5e-66 221.2 0.0 5.6e-66 221.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CEH17874.1 - 3e-09 36.3 0.0 3.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CEH17874.1 - 5.4e-09 35.2 0.1 1.5e-05 23.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CEH17874.1 - 4.4e-08 33.6 0.0 6.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CEH17874.1 - 1.1e-07 31.4 0.0 1.2e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CEH17874.1 - 1.1e-06 28.6 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CEH17874.1 - 7.3e-05 22.0 0.0 7.6e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEH17874.1 - 0.0031 16.9 0.0 0.11 11.8 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CEH17874.1 - 0.025 14.0 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation EF-hand_5 PF13202.1 CEH17874.1 - 0.094 12.0 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 EF hand MFS_1 PF07690.11 CEH17875.1 - 4.5e-20 71.6 30.1 4.1e-17 61.9 9.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CEH17875.1 - 2.7e-19 69.4 7.8 7e-19 68.0 1.9 2.4 2 0 0 2 2 2 2 Nodulin-like GFO_IDH_MocA PF01408.17 CEH17876.1 - 8.6e-12 45.6 1.2 6.3e-11 42.8 0.8 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.1 CEH17876.1 - 0.076 13.1 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 CoA binding domain Sugar_tr PF00083.19 CEH17877.1 - 7.5e-75 252.2 11.5 1.2e-54 185.6 1.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CEH17877.1 - 1e-12 47.4 28.8 5.2e-12 45.1 20.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CEH17877.1 - 0.0011 17.3 0.2 0.0015 16.7 0.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LSM PF01423.17 CEH17878.1 - 2.5e-13 49.3 0.0 3.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CEH17878.1 - 0.057 13.3 0.1 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain DnaJ PF00226.26 CEH17882.1 - 4.3e-22 77.6 0.3 7.5e-22 76.8 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain AA_permease_2 PF13520.1 CEH17885.1 - 2e-59 201.2 39.6 2.4e-59 200.9 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CEH17885.1 - 5.5e-30 104.1 35.2 6.8e-30 103.8 24.4 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_8 PF08022.7 CEH17886.1 - 9e-16 57.6 0.0 1.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CEH17886.1 - 7.4e-11 42.1 0.0 8.4e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CEH17886.1 - 2.1e-10 40.7 12.3 2.1e-10 40.7 8.5 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Polysacc_deac_1 PF01522.16 CEH17887.1 - 4.3e-27 94.1 0.0 6.7e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase HAMP PF00672.20 CEH17888.1 - 2.8e-47 158.7 19.4 3e-08 33.7 0.2 8.0 7 0 0 7 7 7 7 HAMP domain HATPase_c PF02518.21 CEH17888.1 - 3.7e-27 94.2 0.0 1.4e-26 92.3 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CEH17888.1 - 1.1e-26 93.0 1.5 1.3e-23 83.1 0.4 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 CEH17888.1 - 3.4e-17 62.2 3.9 4.2e-16 58.6 0.2 4.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Pox_A_type_inc PF04508.7 CEH17888.1 - 0.018 14.7 0.1 0.46 10.3 0.0 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TMF_TATA_bd PF12325.3 CEH17888.1 - 0.18 11.5 3.8 2.9 7.6 0.0 4.0 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding PMC2NT PF08066.7 CEH17888.1 - 0.48 10.7 4.9 4.8 7.5 0.0 4.2 5 0 0 5 5 5 0 PMC2NT (NUC016) domain Syntaxin PF00804.20 CEH17888.1 - 0.81 9.8 7.3 19 5.5 1.7 4.7 3 2 0 3 3 3 0 Syntaxin ALS_ss_C PF10369.4 CEH17890.1 - 5.9e-22 77.1 0.1 5.4e-19 67.7 0.0 2.3 2 0 0 2 2 2 2 Small subunit of acetolactate synthase Med3 PF11593.3 CEH17890.1 - 0.024 13.9 1.0 0.028 13.6 0.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SoxG PF04268.7 CEH17890.1 - 0.024 14.4 0.5 0.041 13.7 0.4 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family DnaJ PF00226.26 CEH17891.1 - 1.4e-23 82.3 0.4 2.5e-23 81.5 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CEH17891.1 - 1.1e-22 79.7 0.2 2.2e-19 69.1 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CEH17891.1 - 8.6e-13 48.1 19.3 1.7e-12 47.1 13.4 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CEH17891.1 - 0.86 9.3 10.9 1.9 8.2 2.2 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Aconitase PF00330.15 CEH17892.1 - 1.4e-150 501.8 0.0 4e-150 500.3 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CEH17892.1 - 9.6e-32 109.8 0.0 2.2e-31 108.6 0.0 1.6 2 0 0 2 2 2 1 Aconitase C-terminal domain MRP-L28 PF09812.4 CEH17892.1 - 1.4e-08 34.6 5.7 7.1e-07 29.1 0.6 3.2 3 0 0 3 3 3 2 Mitochondrial ribosomal protein L28 HlyD_2 PF12700.2 CEH17893.1 - 0.23 10.5 2.6 0.11 11.5 0.3 1.5 2 0 0 2 2 2 0 HlyD family secretion protein RNA_pol_Rpb6 PF01192.17 CEH17894.1 - 4.3e-24 84.0 0.2 6.5e-24 83.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Phage-tail_3 PF13550.1 CEH17894.1 - 0.11 12.2 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Putative phage tail protein Pro_isomerase PF00160.16 CEH17895.1 - 1.3e-47 161.8 0.0 1.5e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HATPase_c PF02518.21 CEH17896.1 - 1.4e-16 60.2 0.2 2.9e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 CEH17896.1 - 3.8e-16 58.8 0.0 1.1e-15 57.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 CEH17896.1 - 4.1e-15 55.7 0.0 1.1e-09 38.2 0.0 2.9 3 0 0 3 3 3 2 Response regulator receiver domain GAF PF01590.21 CEH17896.1 - 0.001 19.2 0.6 0.0083 16.2 0.0 2.8 3 0 0 3 3 3 1 GAF domain Na_H_Exchanger PF00999.16 CEH17897.1 - 1.6e-66 224.3 50.0 2.1e-66 224.0 34.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3445 PF11927.3 CEH17898.1 - 1.1e-34 119.9 0.0 5.7e-31 107.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3445) EPSP_synthase PF00275.15 CEH17901.1 - 1.1e-96 323.9 2.8 1.2e-96 323.7 1.9 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) BcsB PF03170.8 CEH17901.1 - 0.036 12.0 0.3 0.057 11.4 0.2 1.2 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit EAP30 PF04157.11 CEH17903.1 - 1.1e-40 139.1 0.0 1.4e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Ish1 PF10281.4 CEH17904.1 - 1.7e-41 139.8 10.8 2.2e-07 30.8 0.1 7.4 6 1 1 7 7 7 6 Putative stress-responsive nuclear envelope protein 6PGD PF00393.14 CEH17904.1 - 4.5e-05 22.8 5.7 0.11 11.7 0.0 3.3 2 1 1 3 3 3 3 6-phosphogluconate dehydrogenase, C-terminal domain Peptidase_M19 PF01244.16 CEH17905.1 - 6.9e-92 307.7 0.0 8e-92 307.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) E1_DerP2_DerF2 PF02221.10 CEH17906.1 - 2.1e-25 89.5 0.1 2.9e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 CEH17906.1 - 0.0011 19.0 0.0 0.0035 17.3 0.0 1.7 1 1 1 2 2 2 1 ML-like domain Pdase_C33_assoc PF14756.1 CEH17906.1 - 0.089 12.5 0.6 0.25 11.0 0.4 1.8 1 0 0 1 1 1 0 Peptidase_C33-associated domain GTP_EFTU PF00009.22 CEH17907.1 - 2.4e-31 108.6 0.0 1.4e-30 106.0 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CEH17907.1 - 9.1e-15 54.5 4.2 1.5e-10 41.0 0.2 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF-2 PF11987.3 CEH17907.1 - 1.5e-12 47.3 0.0 3.7e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 ATP_bind_1 PF03029.12 CEH17907.1 - 0.012 15.1 0.0 0.03 13.8 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DDE_2 PF02914.10 CEH17907.1 - 0.15 11.5 3.3 0.33 10.4 2.3 1.5 1 0 0 1 1 1 0 Bacteriophage Mu transposase Pkinase PF00069.20 CEH17908.1 - 1.1e-56 191.9 0.0 3.5e-56 190.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH17908.1 - 9.1e-35 119.9 0.0 1.5e-30 106.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CEH17908.1 - 0.00015 20.8 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CEH17908.1 - 0.0009 18.1 0.1 0.0017 17.2 0.1 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 CEH17908.1 - 0.0042 16.8 0.8 0.084 12.5 0.1 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CEH17908.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 CEH17908.1 - 0.037 13.1 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 CEH17909.1 - 8.6e-05 22.1 0.9 0.00018 21.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 CEH17909.1 - 0.012 15.4 6.7 0.62 10.0 0.5 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat CoA_trans PF01144.18 CEH17911.1 - 3.1e-100 333.8 0.5 4.9e-60 202.4 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CEH17911.1 - 0.02 14.5 0.1 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain SR-25 PF10500.4 CEH17911.1 - 0.12 11.8 6.3 0.24 10.8 4.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BRAP2 PF07576.7 CEH17912.1 - 3.2e-21 74.9 0.0 6.3e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 CEH17912.1 - 5.2e-18 64.9 4.3 1.1e-17 63.8 3.0 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 CEH17912.1 - 1.3e-08 34.5 10.1 3.5e-08 33.1 7.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CEH17912.1 - 0.0001 21.9 6.9 0.0001 21.9 4.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CEH17912.1 - 0.00015 21.3 6.9 0.00034 20.1 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CCDC155 PF14662.1 CEH17912.1 - 0.00025 20.7 7.2 0.00041 19.9 5.0 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 zf-rbx1 PF12678.2 CEH17912.1 - 0.00033 20.7 4.6 0.00033 20.7 3.2 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CEH17912.1 - 0.0012 18.8 8.5 0.0012 18.8 5.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEH17912.1 - 0.0012 18.4 7.1 0.0012 18.4 4.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CEH17912.1 - 0.0076 16.0 4.4 0.021 14.6 2.5 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_6 PF14259.1 CEH17912.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_UBOX PF13445.1 CEH17912.1 - 0.077 12.7 2.5 0.27 10.9 0.8 2.3 1 1 1 2 2 2 0 RING-type zinc-finger Baculo_RING PF05883.6 CEH17912.1 - 0.088 12.6 0.9 0.16 11.8 0.6 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 CEH17912.1 - 0.18 11.3 6.7 0.48 10.0 4.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ArfGap PF01412.13 CEH17912.1 - 0.49 10.1 4.1 0.12 12.1 0.3 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Prefoldin_2 PF01920.15 CEH17912.1 - 1.4 8.7 7.3 3.8 7.3 0.2 3.0 2 1 1 3 3 3 0 Prefoldin subunit Sugarporin_N PF11471.3 CEH17912.1 - 1.5 8.4 7.8 0.5 10.0 0.8 2.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension FUSC PF04632.7 CEH17912.1 - 2.1 6.6 6.8 3.5 5.9 4.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 CEH17912.1 - 3 7.4 11.8 5.9 6.4 8.2 1.5 1 0 0 1 1 1 0 IncA protein AIG2 PF06094.7 CEH17913.1 - 9.1e-07 29.3 0.0 1.3e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 AIG2-like family RRM_1 PF00076.17 CEH17914.1 - 1.7e-18 65.9 0.0 2.5e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH17914.1 - 8.1e-15 54.5 0.0 1.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH17914.1 - 6.8e-09 35.4 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 CEH17914.1 - 0.0001 22.5 1.5 0.00023 21.3 1.1 1.6 1 1 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Chromo PF00385.19 CEH17915.1 - 0.00012 21.6 0.8 0.00024 20.7 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TauD PF02668.11 CEH17916.1 - 4.1e-37 128.2 0.0 5.9e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 CEH17916.1 - 1.2e-06 28.7 0.5 5.6e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF971) SHR3_chaperone PF08229.6 CEH17920.1 - 7.9e-26 90.2 0.2 3.8e-25 87.9 0.2 1.8 1 1 0 1 1 1 1 ER membrane protein SH3 OST3_OST6 PF04756.8 CEH17921.1 - 3.4e-20 72.2 1.9 5.7e-20 71.4 1.3 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 CEH17921.1 - 0.00026 20.6 0.0 0.00062 19.4 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.1 CEH17921.1 - 0.055 12.9 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Imm6 PF14434.1 CEH17921.1 - 0.23 11.1 0.2 0.72 9.5 0.0 1.9 3 0 0 3 3 3 0 Immunity protein Imm6 TrbC PF04956.8 CEH17921.1 - 1.7 8.7 7.7 0.31 11.0 2.2 2.1 2 0 0 2 2 2 0 TrbC/VIRB2 family Sec7_N PF12783.2 CEH17922.1 - 5.2e-28 97.5 0.0 1.6e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CEH17922.1 - 0.00049 19.5 0.0 0.0019 17.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Urb2 PF10441.4 CEH17922.1 - 0.00073 19.2 0.1 0.0033 17.0 0.0 2.2 1 0 0 1 1 1 1 Urb2/Npa2 family WD40 PF00400.27 CEH17923.1 - 5.2e-42 140.2 18.1 7.8e-08 31.9 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CEH17923.1 - 0.036 12.8 0.0 0.088 11.5 0.0 1.7 2 0 0 2 2 2 0 Nup133 N terminal like p450 PF00067.17 CEH17926.1 - 1.4e-22 79.8 0.0 1.8e-21 76.1 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 CEH17927.1 - 4.4e-11 42.9 0.1 1e-10 41.8 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CEH17927.1 - 0.00022 21.3 0.1 0.013 15.5 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 CEH17927.1 - 0.0023 17.6 0.1 0.0042 16.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CEH17927.1 - 0.0034 17.7 0.1 0.0084 16.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 CEH17927.1 - 0.0099 15.5 0.1 0.028 14.0 0.1 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 CEH17927.1 - 0.011 15.8 0.2 0.051 13.6 0.1 2.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 CEH17927.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HIG_1_N PF04588.8 CEH17928.1 - 1.4e-05 24.7 0.5 4e-05 23.2 0.3 1.9 1 0 0 1 1 1 1 Hypoxia induced protein conserved region CFEM PF05730.6 CEH17929.1 - 0.00025 20.8 10.0 0.00041 20.1 7.0 1.4 1 0 0 1 1 1 1 CFEM domain GRP PF07172.6 CEH17929.1 - 0.03 14.7 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycine rich protein family Toxin_3 PF00537.13 CEH17929.1 - 1 9.3 8.2 0.21 11.5 3.1 1.8 1 1 0 1 1 1 0 Scorpion toxin-like domain Secretin_N_2 PF07655.8 CEH17929.1 - 3.1 8.2 13.4 3.1 8.2 1.0 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Serglycin PF04360.7 CEH17929.1 - 3.3 7.4 8.6 2.4 7.8 0.4 2.3 2 0 0 2 2 2 0 Serglycin TIL PF01826.12 CEH17929.1 - 5.3 7.2 10.4 6.7 6.9 6.3 1.8 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain DUF1180 PF06679.7 CEH17929.1 - 8.9 6.1 8.3 1.8 8.4 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Sec3_C PF09763.4 CEH17930.1 - 4.7e-180 600.1 0.0 6.2e-180 599.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 CEH17930.1 - 5.1e-21 74.3 0.0 1.1e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 CEH17930.1 - 0.033 12.7 0.2 0.055 11.9 0.2 1.2 1 0 0 1 1 1 0 Vps52 / Sac2 family Tetraspannin PF00335.15 CEH17931.1 - 7.6e-15 54.7 3.3 1.1e-14 54.2 2.3 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3237 PF11578.3 CEH17931.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) AAA_13 PF13166.1 CEH17933.1 - 1.2e-05 23.9 28.1 1.2e-05 23.9 19.4 6.6 2 2 2 5 5 5 4 AAA domain Reo_sigmaC PF04582.7 CEH17933.1 - 4.8e-05 22.7 62.9 0.00015 21.0 2.8 6.9 3 1 3 7 7 7 5 Reovirus sigma C capsid protein Pox_A_type_inc PF04508.7 CEH17933.1 - 0.041 13.6 0.3 0.041 13.6 0.2 13.8 15 2 2 17 17 17 0 Viral A-type inclusion protein repeat LSM PF01423.17 CEH17934.1 - 7.9e-18 63.7 0.7 1.1e-17 63.3 0.5 1.2 1 0 0 1 1 1 1 LSM domain Asp_Glu_race PF01177.17 CEH17935.1 - 9.8e-18 64.8 0.2 1.4e-17 64.3 0.1 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Allantoicase PF03561.10 CEH17936.1 - 2.1e-82 274.0 0.0 1e-41 141.9 0.0 2.3 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 CEH17936.1 - 1.5e-40 138.2 0.0 2.2e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate hydrolase DUF3580 PF12117.3 CEH17936.1 - 0.027 14.3 0.4 0.067 13.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) Transp_cyt_pur PF02133.10 CEH17938.1 - 4.5e-119 397.8 34.9 5.2e-119 397.6 24.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin WD40 PF00400.27 CEH17939.1 - 8.7e-38 126.8 2.7 3e-07 30.0 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Prp19 PF08606.6 CEH17939.1 - 6.5e-29 99.4 0.2 1.1e-28 98.7 0.1 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 CEH17939.1 - 0.0052 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain Nucleoporin_N PF08801.6 CEH17939.1 - 0.018 13.7 0.0 5.1 5.7 0.0 2.9 2 1 0 3 3 3 0 Nup133 N terminal like zf-Nse PF11789.3 CEH17939.1 - 0.19 11.2 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L18e PF00828.14 CEH17940.1 - 1.3e-21 77.3 0.0 2.3e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Abhydrolase_5 PF12695.2 CEH17941.1 - 3.3e-22 78.8 0.0 5.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH17941.1 - 8.9e-17 61.7 0.0 9e-15 55.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH17941.1 - 3.9e-06 26.5 0.0 0.00017 21.2 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 CEH17941.1 - 6.1e-05 22.8 0.0 0.00017 21.3 0.0 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 CEH17941.1 - 0.00025 19.6 0.0 0.0036 15.8 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF818 PF05677.7 CEH17941.1 - 0.00039 19.2 0.0 0.00056 18.7 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 CEH17941.1 - 0.002 17.4 0.0 0.057 12.7 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 CEH17941.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEH17941.1 - 0.019 14.1 0.0 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.8 CEH17941.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) zf-RING_2 PF13639.1 CEH17942.1 - 1.3e-06 28.1 6.2 3e-06 26.9 3.6 2.2 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 CEH17942.1 - 9.7e-06 25.6 0.2 1.9e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger Baculo_RING PF05883.6 CEH17942.1 - 6.2e-05 22.8 0.1 0.0001 22.1 0.1 1.3 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain zf-Apc11 PF12861.2 CEH17942.1 - 7.6e-05 22.4 0.8 0.00015 21.5 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 CEH17942.1 - 0.0033 17.1 0.3 0.0058 16.3 0.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.3 CEH17942.1 - 0.009 15.9 2.5 0.017 15.0 1.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 CEH17942.1 - 0.066 12.8 5.8 0.11 12.1 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 CEH17942.1 - 0.075 13.0 5.3 0.14 12.2 3.7 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.1 CEH17942.1 - 0.21 11.2 3.5 0.41 10.3 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CEH17942.1 - 0.5 10.0 3.7 0.89 9.3 2.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.1 CEH17942.1 - 1.8 8.6 7.4 3.7 7.6 4.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PRCC PF10253.4 CEH17943.1 - 5.8e-09 36.8 17.9 5.8e-09 36.8 12.4 3.8 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF4035 PF13227.1 CEH17943.1 - 0.3 10.4 2.9 0.78 9.1 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) Sec16_C PF12931.2 CEH17944.1 - 5.8e-73 246.0 0.0 8e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CEH17944.1 - 7.3e-18 64.6 0.0 1.7e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region CLN3 PF02487.12 CEH17945.1 - 1.5e-71 241.2 2.0 2e-61 207.9 0.0 3.2 1 1 2 3 3 3 3 CLN3 protein zf-RING_4 PF14570.1 CEH17947.1 - 6e-21 73.7 12.0 9.7e-21 73.0 8.3 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CEH17947.1 - 8.1e-06 25.4 8.8 1.4e-05 24.6 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEH17947.1 - 0.00023 20.9 11.5 0.00042 20.0 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain RRM_1 PF00076.17 CEH17947.1 - 0.0012 18.4 0.0 0.0071 15.9 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH17947.1 - 0.0024 17.6 0.0 0.0091 15.8 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 CEH17947.1 - 0.0064 16.4 12.2 0.013 15.5 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CEH17947.1 - 0.027 14.1 4.2 0.07 12.8 2.9 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 CEH17947.1 - 0.18 11.5 4.1 0.29 10.8 2.8 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 CEH17947.1 - 0.22 11.1 11.4 0.37 10.4 7.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH17947.1 - 5.7 6.7 10.2 10 5.9 7.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain MMR_HSR1 PF01926.18 CEH17948.1 - 1e-17 64.1 0.0 6.5e-15 55.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CEH17948.1 - 1.3e-05 24.5 0.0 0.00023 20.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CEH17948.1 - 3e-05 23.2 0.0 6.2e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CEH17948.1 - 0.018 15.5 1.9 0.024 15.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 CEH17948.1 - 0.02 14.0 0.0 0.02 14.0 0.0 2.0 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.18 CEH17948.1 - 0.021 14.6 0.0 0.021 14.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family cobW PF02492.14 CEH17948.1 - 0.034 13.6 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RRN3 PF05327.6 CEH17948.1 - 0.061 11.4 1.9 0.091 10.8 1.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3402 PF11882.3 CEH17948.1 - 4.5 6.2 6.0 7.6 5.4 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Fungal_trans PF04082.13 CEH17950.1 - 0.0045 15.9 0.0 0.0078 15.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH17950.1 - 0.13 12.1 1.1 0.36 10.7 0.8 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 CEH17952.1 - 4.3e-49 162.7 12.7 1.4e-12 47.0 0.7 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CEH17952.1 - 5.9e-06 25.2 0.1 2.2 6.9 0.0 4.3 1 1 3 4 4 4 3 Nup133 N terminal like DUF3312 PF11768.3 CEH17952.1 - 0.00018 19.8 0.0 0.00027 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Nup160 PF11715.3 CEH17952.1 - 0.0011 17.2 4.0 0.84 7.6 0.1 3.5 2 2 0 3 3 3 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 CEH17952.1 - 0.05 12.3 0.0 0.09 11.5 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Cytochrom_D1 PF02239.11 CEH17952.1 - 0.073 11.3 0.1 2.4 6.3 0.0 3.0 3 1 1 4 4 4 0 Cytochrome D1 heme domain Ribosomal_L37e PF01907.14 CEH17955.1 - 2.4e-25 88.1 13.1 4.6e-25 87.1 9.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 CEH17955.1 - 0.0023 17.7 1.9 0.0035 17.1 1.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 CEH17955.1 - 0.049 13.3 0.1 0.051 13.2 0.1 1.2 1 0 0 1 1 1 0 SelR domain HypA PF01155.14 CEH17955.1 - 0.095 12.3 1.0 0.13 11.9 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF2883 PF11097.3 CEH17955.1 - 1 9.5 4.4 4.5 7.4 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2883) zf-C3HC4 PF00097.20 CEH17955.1 - 1.4 8.6 6.8 2.2 8.0 4.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 CEH17955.1 - 6.4 6.2 10.8 2.2 7.7 0.3 2.7 1 1 1 3 3 3 0 Ribosomal protein S14p/S29e Ribosomal_L7Ae PF01248.21 CEH17956.1 - 2.1e-23 81.6 0.0 2.5e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4083 PF13314.1 CEH17956.1 - 0.077 12.8 0.4 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) FKBP_C PF00254.23 CEH17956.1 - 0.079 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase XRN_N PF03159.13 CEH17957.1 - 1.9e-100 335.1 1.5 2.8e-100 334.5 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus AAA PF00004.24 CEH17958.1 - 1.4e-41 141.7 0.0 2.5e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEH17958.1 - 6.7e-07 29.5 0.3 0.0026 17.8 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 CEH17958.1 - 8.1e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CEH17958.1 - 1.2e-05 24.3 0.0 4.6e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CEH17958.1 - 8e-05 22.7 0.1 0.00057 19.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CEH17958.1 - 0.00016 21.4 0.4 0.0015 18.2 0.2 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CEH17958.1 - 0.00056 19.0 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CEH17958.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CEH17958.1 - 0.0041 16.7 0.1 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEH17958.1 - 0.0054 17.5 1.1 0.01 16.6 0.2 2.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CEH17958.1 - 0.0059 16.4 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CEH17958.1 - 0.0063 15.2 0.2 0.065 11.9 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 CEH17958.1 - 0.0082 15.8 0.4 0.017 14.8 0.3 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CEH17958.1 - 0.0098 16.2 0.2 0.04 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CEH17958.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CEH17958.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 CEH17958.1 - 0.019 13.8 0.0 0.048 12.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 CEH17958.1 - 0.024 13.7 0.5 0.6 9.1 0.1 2.6 2 1 1 3 3 3 0 KaiC AAA_28 PF13521.1 CEH17958.1 - 0.029 14.3 0.4 0.077 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CEH17958.1 - 0.043 13.4 0.2 0.42 10.2 0.1 2.2 1 1 1 2 2 2 0 NACHT domain Histone PF00125.19 CEH17958.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 RNA_helicase PF00910.17 CEH17958.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 CEH17958.1 - 0.073 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 CEH17958.1 - 0.078 12.3 1.0 1.9 7.8 0.2 2.6 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CEH17958.1 - 0.11 12.0 0.1 0.32 10.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CEH17958.1 - 0.12 11.5 0.1 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CEH17958.1 - 0.13 11.4 0.5 0.4 9.8 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein MCM PF00493.18 CEH17959.1 - 3e-144 479.9 0.1 3.7e-144 479.5 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CEH17959.1 - 4e-17 62.8 0.0 1e-16 61.4 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 CEH17959.1 - 4.1e-06 26.5 0.0 9.3e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CEH17959.1 - 5.7e-06 25.6 0.0 0.00062 18.9 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CEH17959.1 - 8.1e-05 22.2 0.1 0.0017 17.9 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 CEH17959.1 - 0.011 16.1 2.1 0.025 14.9 0.4 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CEH17959.1 - 0.04 13.3 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 CEH17959.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TRAPP PF04051.11 CEH17961.1 - 2.5e-26 92.0 0.0 1.1e-25 89.9 0.0 1.8 2 0 0 2 2 2 1 Transport protein particle (TRAPP) component SSP160 PF06933.6 CEH17961.1 - 4.7 5.0 11.7 6.3 4.6 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NUC173 PF08161.7 CEH17962.1 - 3.7e-46 156.9 0.0 6.3e-45 152.9 0.0 3.0 3 1 0 3 3 3 1 NUC173 domain Nucleo_P87 PF07267.6 CEH17962.1 - 0.15 10.7 0.1 0.27 9.8 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SMC_N PF02463.14 CEH17963.1 - 7.2e-64 215.0 0.0 6e-63 212.0 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CEH17963.1 - 1.1e-20 73.7 3.1 1.6e-20 73.2 0.2 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CEH17963.1 - 9.9e-15 55.3 17.6 9.9e-15 55.3 12.2 5.8 1 1 1 2 2 1 1 AAA domain AAA_21 PF13304.1 CEH17963.1 - 7.1e-14 52.4 1.1 3.1e-06 27.3 0.3 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CEH17963.1 - 7.4e-08 31.8 3.2 7.4e-08 31.8 2.2 2.2 2 1 0 2 2 1 1 AAA ATPase domain MscS_porin PF12795.2 CEH17963.1 - 7.9e-07 28.6 28.7 7.9e-07 28.6 19.9 5.8 4 3 1 5 5 4 1 Mechanosensitive ion channel porin domain AAA_29 PF13555.1 CEH17963.1 - 2.1e-05 23.9 0.1 6.5e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CEH17963.1 - 0.00012 21.3 23.5 0.058 12.5 2.6 5.4 4 1 2 6 6 6 2 Reovirus sigma C capsid protein GAS PF13851.1 CEH17963.1 - 0.0031 16.7 10.7 0.0031 16.7 7.4 7.6 3 2 4 7 7 7 3 Growth-arrest specific micro-tubule binding Mit_KHE1 PF10173.4 CEH17963.1 - 0.0097 15.7 0.8 0.0097 15.7 0.5 2.7 3 0 0 3 3 3 1 Mitochondrial K+-H+ exchange-related gpW PF02831.10 CEH17963.1 - 0.051 13.1 13.9 0.59 9.7 0.1 6.0 6 0 0 6 6 6 0 gpW ABC_tran PF00005.22 CEH17963.1 - 0.079 13.2 0.1 0.079 13.2 0.1 5.4 2 2 1 3 3 2 0 ABC transporter DUF4140 PF13600.1 CEH17963.1 - 0.43 11.0 0.0 0.43 11.0 0.0 8.9 6 3 2 9 9 9 0 N-terminal domain of unknown function (DUF4140) AAA_13 PF13166.1 CEH17963.1 - 1.2 7.5 72.0 0.022 13.2 10.6 5.3 3 2 1 5 5 5 0 AAA domain Filament PF00038.16 CEH17963.1 - 2.5 7.5 77.8 1.2 8.5 0.9 6.3 2 2 3 6 6 6 0 Intermediate filament protein NPV_P10 PF05531.7 CEH17963.1 - 3.7 7.8 36.7 3.5 7.9 0.7 8.4 5 4 2 7 7 7 0 Nucleopolyhedrovirus P10 protein OTU PF02338.14 CEH17965.1 - 0.00011 22.7 0.0 0.00018 22.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CEH17965.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain Methyltransf_24 PF13578.1 CEH17965.1 - 0.035 14.9 0.1 0.063 14.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF572 PF04502.8 CEH17966.1 - 0.34 10.0 10.2 0.43 9.7 7.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.8 CEH17966.1 - 5.3 6.8 11.1 8.2 6.2 7.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.6 CEH17966.1 - 7.8 4.6 8.3 9.8 4.3 5.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 OTU PF02338.14 CEH17968.1 - 0.00062 20.3 0.0 0.00075 20.0 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease IBN_N PF03810.14 CEH17968.1 - 0.0066 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain CW_binding_2 PF04122.7 CEH17968.1 - 0.082 13.1 0.1 0.2 11.8 0.0 1.6 1 1 1 2 2 2 0 Putative cell wall binding repeat 2 rve PF00665.21 CEH17972.1 - 1.7e-16 60.4 0.0 4.8e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEH17972.1 - 0.00062 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RWP-RK PF02042.10 CEH17972.1 - 0.018 14.8 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 0 RWP-RK domain Asp_protease_2 PF13650.1 CEH17972.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_3 PF13917.1 CEH17973.1 - 0.02 14.5 0.1 0.057 13.1 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 CEH17973.1 - 0.16 11.9 5.7 0.28 11.1 4.0 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 CEH17974.1 - 4.7e-40 137.1 0.0 1.8e-30 105.7 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CEH17975.1 - 1.2e-26 93.1 0.0 1.5e-25 89.6 0.0 2.6 2 1 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 CEH17975.1 - 1.5e-09 37.4 0.0 2.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CEH17975.1 - 2.7e-08 33.6 0.0 4.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CEH17975.1 - 2.9e-07 30.0 0.0 7e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CEH17975.1 - 0.00013 21.3 0.0 0.00029 20.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain eIF3g PF12353.3 CEH17975.1 - 0.13 12.1 0.1 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF3681 PF12442.3 CEH17976.1 - 0.021 14.9 1.4 0.26 11.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) DUF4149 PF13664.1 CEH17976.1 - 0.036 14.1 10.6 1.6 8.8 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) PRRSV_2b PF07069.6 CEH17976.1 - 0.56 10.5 3.8 5.9 7.2 0.2 2.8 1 1 1 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Integrase_DNA PF02920.10 CEH17977.1 - 0.041 13.2 1.5 0.066 12.6 1.0 1.3 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase Oxidored-like PF09791.4 CEH17980.1 - 8.9e-08 31.4 5.3 1.8e-07 30.4 3.7 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal WD40 PF00400.27 CEH17981.1 - 4.3e-07 29.5 2.6 0.028 14.2 0.2 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat DNApol3-delta_C PF09115.5 CEH17981.1 - 0.0056 16.7 0.4 0.0099 15.9 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit, C terminal DUF4407 PF14362.1 CEH17981.1 - 0.13 11.1 2.8 0.21 10.5 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4589 PF15252.1 CEH17981.1 - 5.1 6.8 11.2 9 6.0 1.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4589) Y_phosphatase PF00102.22 CEH17982.1 - 9.6e-26 90.5 1.2 5.2e-16 58.6 0.0 3.1 2 1 0 3 3 3 3 Protein-tyrosine phosphatase MFS_1 PF07690.11 CEH17983.1 - 1.9e-32 112.3 77.8 6.1e-31 107.4 34.0 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Aconitase PF00330.15 CEH17984.1 - 2.3e-183 609.9 0.0 2.9e-183 609.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CEH17984.1 - 2e-34 118.5 0.0 3.7e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain UQ_con PF00179.21 CEH17986.1 - 1.5e-18 66.5 0.0 1.8e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.13 CEH17986.1 - 0.049 12.7 1.4 0.094 11.8 0.1 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others ETF PF01012.16 CEH17989.1 - 1.3e-34 119.2 2.3 1.7e-34 118.8 1.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain EF-hand_7 PF13499.1 CEH17991.1 - 5e-07 29.7 0.6 1.5e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair RRM_6 PF14259.1 CEH17991.1 - 1.6e-06 27.9 0.0 7.5e-06 25.8 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EF-hand_5 PF13202.1 CEH17991.1 - 3.6e-06 26.0 0.0 0.041 13.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CEH17991.1 - 3.7e-06 26.3 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain RRM_1 PF00076.17 CEH17991.1 - 1.2e-05 24.8 0.0 3.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_1 PF00036.27 CEH17991.1 - 7.2e-05 21.8 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CEH17991.1 - 0.00098 18.6 0.1 0.27 10.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Peptidase_M1 PF01433.15 CEH17992.1 - 2e-110 369.5 0.6 4.5e-66 223.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 CEH17992.1 - 1e-31 110.3 3.6 1.4e-15 57.4 0.3 2.3 1 1 1 2 2 2 2 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CEH17992.1 - 5.2e-13 49.1 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Gcd10p PF04189.8 CEH17993.1 - 7.1e-61 205.9 0.0 5.8e-60 202.9 0.0 1.9 1 1 0 1 1 1 1 Gcd10p family DUF202 PF02656.10 CEH17994.1 - 1.9e-20 72.8 3.9 3.2e-20 72.1 0.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF202) FCD PF07729.7 CEH17994.1 - 0.038 14.3 0.1 0.071 13.4 0.1 1.4 1 1 0 1 1 1 0 FCD domain FA_hydroxylase PF04116.8 CEH17995.1 - 7.5e-15 55.3 17.5 7.5e-15 55.3 12.1 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TIP41 PF04176.8 CEH17996.1 - 2.3e-22 79.1 0.0 1.5e-20 73.2 0.0 2.5 1 1 0 1 1 1 1 TIP41-like family Pex14_N PF04695.8 CEH17997.1 - 1.5e-29 102.8 0.2 1.5e-29 102.8 0.1 2.6 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 CEH17997.1 - 0.0004 20.0 0.2 0.0004 20.0 0.1 1.5 2 0 0 2 2 1 1 IncA protein Atg14 PF10186.4 CEH17997.1 - 0.00068 18.6 0.1 0.00082 18.4 0.1 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 CEH17997.1 - 0.0012 18.5 1.3 0.0034 17.1 0.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Laminin_I PF06008.9 CEH17997.1 - 0.0015 17.9 3.2 0.0023 17.3 2.2 1.2 1 0 0 1 1 1 1 Laminin Domain I Mt_ATP-synt_D PF05873.7 CEH17997.1 - 0.008 15.8 0.7 0.012 15.2 0.5 1.3 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) zf-C4H2 PF10146.4 CEH17997.1 - 0.0086 16.1 0.0 0.032 14.2 0.0 1.8 2 0 0 2 2 2 1 Zinc finger-containing protein Sipho_Gp157 PF05565.6 CEH17997.1 - 0.012 15.2 3.7 0.017 14.7 2.6 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 OmpH PF03938.9 CEH17997.1 - 0.015 15.2 3.2 0.02 14.8 1.1 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ran-binding PF05508.6 CEH17997.1 - 0.019 13.8 3.1 0.034 13.0 2.1 1.3 1 0 0 1 1 1 0 RanGTP-binding protein DUF3584 PF12128.3 CEH17997.1 - 0.026 11.8 3.5 0.036 11.4 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cortex-I_coil PF09304.5 CEH17997.1 - 0.035 14.1 6.7 0.13 12.2 4.3 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil NPV_P10 PF05531.7 CEH17997.1 - 0.054 13.7 7.4 4.5 7.6 2.3 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tektin PF03148.9 CEH17997.1 - 0.062 11.8 4.2 2.5 6.5 0.1 2.1 1 1 1 2 2 2 0 Tektin family Phage_GPO PF05929.6 CEH17997.1 - 0.07 12.3 1.5 0.1 11.8 1.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_13 PF13166.1 CEH17997.1 - 0.076 11.4 1.0 0.1 11.0 0.7 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 CEH17997.1 - 0.077 12.0 5.5 0.11 11.5 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HTH_24 PF13412.1 CEH17997.1 - 0.1 11.9 0.3 0.22 10.9 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sec34 PF04136.10 CEH17997.1 - 0.11 12.1 2.1 0.3 10.7 0.2 2.1 1 1 1 2 2 2 0 Sec34-like family Spc7 PF08317.6 CEH17997.1 - 0.12 10.9 6.1 0.29 9.7 4.3 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Occludin_ELL PF07303.8 CEH17997.1 - 0.49 11.1 3.7 4 8.2 1.2 2.3 1 1 1 2 2 2 0 Occludin homology domain BLOC1_2 PF10046.4 CEH17997.1 - 0.71 10.0 5.3 1.6 8.9 0.3 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 CEH17997.1 - 0.71 9.6 6.1 1.8 8.3 4.1 1.8 1 1 0 1 1 1 0 Laminin Domain II IFT57 PF10498.4 CEH17997.1 - 0.85 8.2 5.8 4.8 5.8 3.8 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 COG2 PF06148.6 CEH17997.1 - 1.1 9.1 8.8 1.6 8.6 2.0 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2317 PF10079.4 CEH17997.1 - 1.2 7.6 4.4 1.9 7.0 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF972 PF06156.8 CEH17997.1 - 1.7 9.0 3.9 8.9 6.7 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF948 PF06103.6 CEH17997.1 - 2.2 8.2 4.7 3.6 7.4 0.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.7 CEH17997.1 - 2.6 7.8 8.0 13 5.5 5.6 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GATase_4 PF13230.1 CEH17998.1 - 8.3e-20 70.5 0.0 1.6e-19 69.6 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 CEH17998.1 - 1.5e-10 41.1 0.0 6.1e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CEH17998.1 - 1.2e-08 34.1 0.2 8.2e-08 31.3 0.0 2.2 2 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_7 PF13537.1 CEH17998.1 - 0.03 14.0 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase domain DUF4203 PF13886.1 CEH17999.1 - 0.0072 15.8 12.4 0.029 13.8 8.3 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4203) DUF1700 PF08006.6 CEH17999.1 - 1.7 7.8 3.8 2.8 7.2 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) PX PF00787.19 CEH18000.1 - 1.4e-17 63.4 0.0 3.5e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 PX domain Atg14 PF10186.4 CEH18000.1 - 0.046 12.6 4.8 7.1 5.4 3.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C4pol PF14260.1 CEH18000.1 - 0.15 12.0 0.2 0.8 9.7 0.0 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Rep_4 PF05797.6 CEH18000.1 - 0.49 9.0 3.4 1.7 7.2 2.3 1.8 1 1 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) ORC3_N PF07034.6 CEH18001.1 - 0.00069 18.6 0.0 0.0043 16.0 0.0 2.1 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus Hairy_orange PF07527.8 CEH18003.1 - 0.15 11.8 2.5 1.8 8.3 0.0 3.4 3 0 0 3 3 3 0 Hairy Orange AAA_17 PF13207.1 CEH18005.1 - 2.7e-05 24.9 0.0 0.00011 22.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 CEH18005.1 - 3.7e-05 23.3 0.0 4.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 CEH18005.1 - 0.00025 19.9 0.0 0.00041 19.2 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 CEH18005.1 - 0.00037 20.5 0.1 0.00054 19.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 CEH18005.1 - 0.0022 16.9 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 CEH18005.1 - 0.0029 17.4 0.2 0.062 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CEH18005.1 - 0.0039 16.3 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CEH18005.1 - 0.005 17.1 0.0 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CEH18005.1 - 0.0076 16.4 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CEH18005.1 - 0.043 12.7 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 CEH18005.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain CPT PF07931.7 CEH18005.1 - 0.068 12.7 0.0 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DDE_3 PF13358.1 CEH18006.1 - 1.8e-15 56.9 0.0 2.3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CEH18006.1 - 0.0096 16.0 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Stimulus_sens_1 PF13756.1 CEH18006.1 - 0.15 12.4 0.1 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Stimulus-sensing domain FBA_3 PF08268.7 CEH18007.1 - 0.0011 18.7 0.3 0.0018 18.0 0.2 1.3 1 0 0 1 1 1 1 F-box associated domain RVT_1 PF00078.22 CEH18008.1 - 4.4e-08 32.7 0.0 7.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2531 PF10748.4 CEH18008.1 - 0.056 12.6 0.1 0.24 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2531) rve PF00665.21 CEH18009.1 - 7.1e-15 55.1 0.0 1.5e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Tim54 PF11711.3 CEH18010.1 - 1.1e-52 178.9 0.0 1.7e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Mito_carr PF00153.22 CEH18012.1 - 6.2e-40 134.8 1.5 1.3e-17 63.3 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2665 PF11654.3 CEH18013.1 - 8.8e-16 57.2 0.1 1.1e-15 56.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) MGC-24 PF05283.6 CEH18014.1 - 0.039 13.7 0.1 0.041 13.6 0.1 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Surp PF01805.15 CEH18015.1 - 4.3e-05 23.0 0.1 9.3e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.17 CEH18015.1 - 0.021 14.4 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad60-SLD PF11976.3 CEH18016.1 - 3.5e-06 26.5 0.0 1e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PXA PF02194.10 CEH18016.1 - 4.4 6.8 7.3 0.34 10.4 0.8 2.0 2 0 0 2 2 2 0 PXA domain BRO1 PF03097.13 CEH18017.1 - 9.8e-91 304.3 2.4 1.8e-90 303.4 0.0 2.5 3 1 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CEH18017.1 - 5.4e-43 147.0 16.6 1e-40 139.5 11.3 2.5 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF2404 PF10296.4 CEH18018.1 - 1.9e-05 24.6 0.0 7.2e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Cupin_2 PF07883.6 CEH18019.1 - 1.3e-27 95.1 0.9 3.2e-14 52.1 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 CEH18019.1 - 8.5e-23 80.3 0.0 1.8e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 CEH18019.1 - 1.3e-08 34.1 0.0 0.0057 16.0 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 CEH18019.1 - 3.6e-07 29.9 0.3 0.00089 18.9 0.0 2.6 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_7 PF12973.2 CEH18019.1 - 0.00018 21.3 0.0 0.32 10.8 0.0 2.7 2 0 0 2 2 2 2 ChrR Cupin-like domain Cupin_6 PF12852.2 CEH18019.1 - 0.0017 18.0 0.0 0.0051 16.4 0.0 1.7 2 0 0 2 2 2 1 Cupin cNMP_binding PF00027.24 CEH18019.1 - 0.029 14.1 0.0 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain MitoNEET_N PF10660.4 CEH18019.1 - 0.057 13.2 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Ectoine_synth PF06339.7 CEH18019.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Ectoine synthase HSF_DNA-bind PF00447.12 CEH18020.1 - 2.3e-33 114.4 0.0 3.4e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding HisG PF01634.13 CEH18024.1 - 3.6e-49 166.4 0.0 5.8e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 CEH18024.1 - 6.8e-24 83.6 0.1 1.5e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 CEH18024.1 - 0.00021 20.9 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Zn_clus PF00172.13 CEH18025.1 - 5.6e-09 35.7 7.5 8.7e-09 35.1 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CEH18025.1 - 7.3e-06 25.0 0.0 1.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain OTU PF02338.14 CEH18027.1 - 5.9e-15 55.9 0.0 1.9e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CEH18027.1 - 0.18 11.1 0.0 1.6 7.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase C65 Otubain E1-E2_ATPase PF00122.15 CEH18028.1 - 2.1e-17 62.9 0.0 2.1e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CEH18028.1 - 1.2e-16 61.7 0.0 1.1e-15 58.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEH18028.1 - 3e-11 43.8 0.1 7e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEH18028.1 - 1.3e-05 25.0 0.0 3.8e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD_2 PF13419.1 CEH18028.1 - 0.0016 18.6 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEH18028.1 - 0.01 15.4 0.1 0.024 14.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RINT1_TIP1 PF04437.8 CEH18029.1 - 2.1e-40 138.7 0.1 7.4e-40 136.9 0.1 1.9 1 1 0 1 1 1 1 RINT-1 / TIP-1 family DUF349 PF03993.7 CEH18029.1 - 0.47 10.6 0.0 0.47 10.6 0.0 4.8 6 1 1 7 7 7 0 Domain of Unknown Function (DUF349) RINT1_TIP1 PF04437.8 CEH18030.1 - 3.8e-12 45.5 0.0 3.8e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Nop PF01798.13 CEH18031.1 - 2.3e-41 140.5 0.2 2.3e-41 140.5 0.1 1.7 2 0 0 2 2 2 1 Putative snoRNA binding domain Prp31_C PF09785.4 CEH18031.1 - 7.8e-38 129.7 3.9 7.8e-38 129.7 2.7 1.6 2 0 0 2 2 2 1 Prp31 C terminal domain NOSIC PF08060.8 CEH18031.1 - 1.1e-19 69.9 0.1 1.8e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain Glycophorin_A PF01102.13 CEH18032.1 - 5.6e-05 22.8 0.1 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 Glycophorin A Syndecan PF01034.15 CEH18032.1 - 0.011 15.3 0.5 0.022 14.3 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain Mid2 PF04478.7 CEH18032.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor POP1 PF06978.6 CEH18032.1 - 0.12 11.9 0.8 0.16 11.6 0.6 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Herpes_gE PF02480.11 CEH18032.1 - 0.13 10.5 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4381 PF14316.1 CEH18032.1 - 0.13 12.3 0.2 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) VSP PF03302.8 CEH18032.1 - 0.15 10.6 0.5 0.25 9.9 0.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein P12 PF12669.2 CEH18032.1 - 0.29 11.3 2.6 0.61 10.3 1.8 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family HAMP PF00672.20 CEH18032.1 - 5.5 7.2 10.4 53 4.0 7.2 2.2 1 1 0 1 1 1 0 HAMP domain WD40 PF00400.27 CEH18033.1 - 6.2e-05 22.7 0.1 0.002 17.9 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat FAD_binding_3 PF01494.14 CEH18034.1 - 3.6e-21 75.6 5.4 4.9e-11 42.2 0.4 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 CEH18034.1 - 0.00013 21.0 0.3 0.00058 18.8 0.1 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CEH18034.1 - 0.00029 19.8 1.9 0.093 11.6 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 CEH18034.1 - 0.00077 19.2 0.0 0.0051 16.5 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 CEH18034.1 - 0.0016 17.3 0.0 0.0029 16.4 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_Gly3P_dh_N PF01210.18 CEH18034.1 - 0.0022 17.7 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 CEH18034.1 - 0.021 14.6 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.1 CEH18034.1 - 0.024 14.7 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH18034.1 - 0.026 14.5 0.0 0.075 13.0 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.12 CEH18034.1 - 0.036 14.4 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 CEH18034.1 - 0.045 14.1 0.0 0.13 12.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CEH18034.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Chitin_synth_1 PF01644.12 CEH18035.1 - 4.5e-87 289.9 0.1 6.7e-87 289.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CEH18035.1 - 9.7e-34 114.9 0.6 2.2e-33 113.7 0.2 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CEH18035.1 - 4.2e-25 88.1 8.4 3.6e-21 75.1 0.4 2.1 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CEH18035.1 - 2.1e-07 30.8 6.6 2.2e-07 30.8 3.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEH18035.1 - 0.0008 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NfeD PF01957.13 CEH18035.1 - 2.4 8.2 9.3 1.3 9.1 3.9 2.4 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Polysacc_deac_1 PF01522.16 CEH18036.1 - 1.1e-26 92.8 0.0 3.8e-26 91.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CEH18036.1 - 0.013 14.3 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 TBP PF00352.16 CEH18038.1 - 1.3e-69 229.5 0.2 1e-34 117.7 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CEH18038.1 - 0.00036 20.5 0.0 0.82 9.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) PIP5K PF01504.13 CEH18039.1 - 7e-61 205.5 0.0 1.1e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CEH18039.1 - 4.3e-19 68.5 0.0 6.3e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tbf5 PF06331.7 CEH18040.1 - 1.8e-20 72.4 0.1 1.9e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Tim17 PF02466.14 CEH18041.1 - 8e-34 116.4 7.3 1.1e-33 116.0 5.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF1620 PF07774.8 CEH18042.1 - 1.6e-50 171.3 0.0 2.8e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CEH18042.1 - 3.4e-08 33.2 12.4 0.00017 21.0 0.5 4.4 3 2 2 5 5 5 3 PQQ-like domain PQQ PF01011.16 CEH18042.1 - 0.00036 19.9 5.6 4.4 7.0 0.0 5.8 7 0 0 7 7 7 3 PQQ enzyme repeat DUF1668 PF07893.8 CEH18042.1 - 0.081 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) COesterase PF00135.23 CEH18045.1 - 1.1e-69 235.5 0.0 1.7e-69 234.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CEH18045.1 - 4.1e-07 29.7 0.1 1.3e-05 24.8 0.1 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold NMT1 PF09084.6 CEH18045.1 - 0.015 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 NMT1/THI5 like Pkinase PF00069.20 CEH18047.1 - 1.5e-72 243.8 0.0 1.9e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH18047.1 - 1.3e-31 109.6 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CEH18047.1 - 8.4e-11 42.2 1.0 1.9e-10 41.0 0.2 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CEH18047.1 - 0.0047 15.9 0.0 0.0086 15.0 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CEH18047.1 - 0.043 13.5 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CEH18047.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GST_N_3 PF13417.1 CEH18048.1 - 8.4e-25 86.8 0.0 3.7e-24 84.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEH18048.1 - 1.4e-16 60.2 0.1 4.9e-15 55.2 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CEH18048.1 - 2.8e-07 30.5 0.0 6.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CEH18048.1 - 0.003 17.5 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 CEH18048.1 - 0.008 16.0 0.6 0.023 14.6 0.4 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CEH18048.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Acyl_transf_3 PF01757.17 CEH18049.1 - 4.1e-05 22.5 7.0 4.1e-05 22.5 4.9 2.4 1 1 0 2 2 2 1 Acyltransferase family CoA_binding_3 PF13727.1 CEH18049.1 - 4.7 7.0 10.3 7.3 6.3 4.2 2.5 2 0 0 2 2 2 0 CoA-binding domain Glyco_tranf_2_3 PF13641.1 CEH18050.1 - 1.9e-14 54.0 0.4 4.9e-07 29.7 0.1 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CEH18050.1 - 5.3e-10 39.3 7.4 5.3e-10 39.3 5.1 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Histone PF00125.19 CEH18051.1 - 6.5e-20 71.0 0.1 8.9e-20 70.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CEH18051.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Acyl_transf_3 PF01757.17 CEH18054.1 - 7.7e-17 61.1 31.6 2e-16 59.7 21.9 1.7 1 1 0 1 1 1 1 Acyltransferase family Glyco_transf_20 PF00982.16 CEH18055.1 - 2e-153 511.2 0.0 2.8e-153 510.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CEH18055.1 - 6.3e-24 84.1 0.0 1.1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 CEH18055.1 - 0.0066 16.0 0.0 0.015 14.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF89 PF01937.14 CEH18056.1 - 2.6e-105 352.1 0.5 3.3e-105 351.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Colicin_Ia PF11504.3 CEH18057.1 - 0.057 13.3 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Colicin Ia Cation_efflux PF01545.16 CEH18058.1 - 1.7e-12 47.0 2.6 2.7e-12 46.3 1.8 1.3 1 0 0 1 1 1 1 Cation efflux family Transket_pyr PF02779.19 CEH18059.1 - 2.2e-63 212.9 0.0 3.8e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CEH18059.1 - 2.7e-61 206.9 0.0 3.6e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Myb_DNA-binding PF00249.26 CEH18062.1 - 6.3e-16 58.1 0.0 5.5e-07 29.5 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CEH18062.1 - 2.9e-12 46.4 0.0 9.5e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain AMMECR1 PF01871.12 CEH18063.1 - 0.1 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 AMMECR1 Meiosis_expr PF15163.1 CEH18064.1 - 0.12 12.7 0.1 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 Meiosis-expressed DUF1749 PF08538.5 CEH18066.1 - 6.8e-50 169.6 0.0 2e-48 164.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 CEH18066.1 - 1.4e-09 38.1 0.0 2.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH18066.1 - 4e-08 33.1 0.0 7.3e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CEH18066.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.15 CEH18066.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold EF-hand_1 PF00036.27 CEH18068.1 - 3.7e-27 91.5 9.0 3.1e-08 32.3 0.0 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 CEH18068.1 - 2.9e-23 81.7 4.8 4.4e-14 52.3 0.3 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CEH18068.1 - 4.6e-22 75.8 4.3 3.8e-06 26.3 0.1 5.3 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 CEH18068.1 - 1.7e-15 56.3 5.8 4.7e-06 26.1 0.1 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CEH18068.1 - 1.7e-13 49.1 12.7 0.00019 20.6 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 CEH18068.1 - 3.2e-08 33.2 3.7 0.006 16.2 0.0 4.0 1 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CEH18068.1 - 0.0018 18.2 0.8 0.46 10.5 0.0 3.1 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CEH18068.1 - 0.0025 17.6 0.7 0.16 11.8 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain EF-hand_2 PF09068.6 CEH18068.1 - 0.021 14.8 0.0 1.6 8.7 0.0 2.9 3 1 0 3 3 3 0 EF hand Mad3_BUB1_II PF08171.6 CEH18068.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 EF-hand_3 PF09069.6 CEH18068.1 - 0.1 12.6 0.1 0.39 10.8 0.0 1.8 2 1 0 2 2 2 0 EF-hand DUF1679 PF07914.6 CEH18068.1 - 0.16 10.5 0.5 0.69 8.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Phage_B PF02304.10 CEH18071.1 - 0.023 14.9 1.9 0.13 12.5 0.1 3.3 2 1 1 3 3 3 0 Scaffold protein B Synaptobrevin PF00957.16 CEH18072.1 - 7.2e-33 112.0 1.3 8.2e-33 111.8 0.9 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.1 CEH18072.1 - 0.022 13.3 0.2 0.027 13.0 0.2 1.0 1 0 0 1 1 1 0 TMEM117 protein family CK_II_beta PF01214.13 CEH18073.1 - 1.3e-73 246.3 0.0 1.7e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CSTF2_hinge PF14327.1 CEH18074.1 - 1.1e-29 102.3 1.9 2.1e-29 101.4 1.3 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 CEH18074.1 - 2.2e-20 72.0 0.0 3.3e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH18074.1 - 7.5e-16 57.8 0.0 1.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH18074.1 - 2.3e-09 36.9 0.0 3.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 CEH18074.1 - 4.7e-07 28.9 4.8 4.7e-07 28.9 3.4 2.8 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal DUF2249 PF10006.4 CEH18074.1 - 0.0032 16.9 0.0 0.38 10.3 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2249) MRP-L27 PF09809.4 CEH18075.1 - 0.00033 20.2 0.3 0.0046 16.5 0.2 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF3535 PF12054.3 CEH18076.1 - 9.9e-100 334.2 3.4 3.4e-98 329.1 0.1 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 CEH18076.1 - 2e-73 246.8 0.0 2.8e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEH18076.1 - 1.5e-12 47.2 0.0 4.2e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 CEH18076.1 - 1.6e-12 46.4 31.3 0.17 12.0 0.2 11.2 10 1 1 11 11 11 6 HEAT repeat Vac14_Fab1_bd PF12755.2 CEH18076.1 - 3e-09 37.1 0.1 0.011 16.1 0.0 3.4 2 1 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 CEH18076.1 - 4.9e-05 23.5 34.6 0.3 11.3 0.2 8.4 6 3 2 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 CEH18076.1 - 0.0068 16.8 40.9 0.2 12.2 0.1 10.6 11 1 1 12 12 12 4 HEAT-like repeat Ipi1_N PF12333.3 CEH18076.1 - 0.033 14.1 7.2 9.2 6.2 0.0 5.0 3 1 1 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Formyl_trans_N PF00551.14 CEH18077.1 - 2.6e-34 118.3 0.0 1.9e-16 60.1 0.1 2.5 2 0 0 2 2 2 2 Formyl transferase NuA4 PF09340.5 CEH18078.1 - 1.3e-18 66.3 0.3 2.1e-18 65.6 0.2 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 HlyD_2 PF12700.2 CEH18078.1 - 0.15 11.1 0.6 0.2 10.8 0.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein cEGF PF12662.2 CEH18079.1 - 0.066 12.8 2.6 0.17 11.5 1.8 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like hEGF PF12661.2 CEH18079.1 - 2.5 8.3 8.0 0.27 11.3 0.9 2.5 2 0 0 2 2 2 0 Human growth factor-like EGF Plant_zn_clust PF10533.4 CEH18079.1 - 3.6 7.2 8.7 0.51 10.0 2.8 2.0 2 0 0 2 2 2 0 Plant zinc cluster domain SUZ PF12752.2 CEH18080.1 - 3.3e-11 43.5 1.1 3.3e-11 43.5 0.7 3.9 5 1 0 5 5 5 1 SUZ domain DUF572 PF04502.8 CEH18080.1 - 4 6.5 8.0 2.6 7.1 4.4 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Aa_trans PF01490.13 CEH18081.1 - 4e-68 229.7 17.8 5.8e-68 229.2 12.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LZ_Tnp_IS66 PF13007.2 CEH18081.1 - 5.2 7.8 5.3 8.3 7.1 0.1 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain NOT2_3_5 PF04153.13 CEH18082.1 - 6e-37 126.5 0.3 6e-37 126.5 0.2 1.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF1191 PF06697.7 CEH18083.1 - 0.0029 16.4 0.6 0.0046 15.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Vpu PF00558.14 CEH18083.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Vpu protein EphA2_TM PF14575.1 CEH18083.1 - 0.024 15.0 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MFS_1 PF07690.11 CEH18083.1 - 0.034 12.8 0.0 0.043 12.5 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Herpes_gE PF02480.11 CEH18083.1 - 0.048 11.9 0.9 0.063 11.5 0.4 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E OSTbeta PF15048.1 CEH18083.1 - 0.069 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF1049 PF06305.6 CEH18083.1 - 0.097 12.1 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Sec1 PF00995.18 CEH18084.1 - 6.8e-144 480.5 0.0 8.9e-144 480.1 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Dioxygenase_C PF00775.16 CEH18085.1 - 2e-07 30.4 0.1 4.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase Cytochrom_B561 PF03188.11 CEH18086.1 - 6.2e-07 29.3 12.3 1.6e-06 28.0 8.6 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 CEH18086.1 - 4.4e-05 22.9 3.9 4.4e-05 22.9 2.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.12 CEH18086.1 - 0.00013 21.8 0.1 0.00024 21.0 0.1 1.3 1 0 0 1 1 1 1 DOMON domain ATPase_gene1 PF09527.5 CEH18086.1 - 0.0004 20.1 4.8 0.0022 17.7 3.3 2.3 1 0 0 1 1 1 1 Putative F0F1-ATPase subunit (ATPase_gene1) Cation_efflux PF01545.16 CEH18086.1 - 0.052 12.6 1.1 0.12 11.3 0.0 1.9 2 0 0 2 2 2 0 Cation efflux family Protocadherin PF08374.6 CEH18086.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Protocadherin L_HGMIC_fpl PF10242.4 CEH18086.1 - 1.3 9.0 7.2 1.6 8.7 0.2 2.4 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein DSPc PF00782.15 CEH18087.1 - 2e-21 75.9 0.0 3.3e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CEH18087.1 - 0.00027 20.3 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CEH18087.1 - 0.01 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 CEH18087.1 - 0.018 13.9 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Myotub-related PF06602.9 CEH18087.1 - 0.063 12.0 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 CEH18087.1 - 0.13 12.4 0.1 0.49 10.6 0.1 2.0 1 1 0 1 1 1 0 Tyrosine phosphatase family ABM PF03992.11 CEH18088.1 - 7.5e-06 25.8 0.0 9.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ADH_zinc_N PF00107.21 CEH18089.1 - 1.9e-10 40.4 0.1 3.2e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CEH18089.1 - 0.00032 20.7 0.1 0.0018 18.3 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding ADH_N PF08240.7 CEH18089.1 - 0.00077 19.2 0.0 0.094 12.4 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CEH18089.1 - 0.012 15.8 0.1 0.045 14.0 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 CEH18089.1 - 0.023 15.5 0.0 0.1 13.4 0.0 2.1 1 1 1 2 2 2 0 Zinc-binding dehydrogenase DapB_N PF01113.15 CEH18089.1 - 0.079 12.8 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus VIT1 PF01988.14 CEH18090.1 - 3.4e-67 226.0 4.1 4.2e-67 225.7 2.8 1.1 1 0 0 1 1 1 1 VIT family TSP9 PF11493.3 CEH18090.1 - 0.11 13.1 0.1 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Lactonase PF10282.4 CEH18091.1 - 2.5e-22 79.4 0.0 5.5e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller MRJP PF03022.11 CEH18091.1 - 0.19 10.8 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Major royal jelly protein EthD PF07110.6 CEH18092.1 - 4e-06 27.6 0.3 0.011 16.6 0.1 2.5 2 0 0 2 2 2 2 EthD domain MutS_V PF00488.16 CEH18094.1 - 2.5e-56 190.7 0.0 3.9e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V PRP21_like_P PF12230.3 CEH18094.1 - 5.9e-52 176.4 4.4 5e-51 173.4 3.1 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CEH18094.1 - 2.3e-48 161.6 5.8 1.2e-17 63.2 0.1 3.5 2 1 1 3 3 3 3 Surp module MutS_III PF05192.13 CEH18094.1 - 3.2e-12 46.6 1.3 3.2e-12 46.6 0.9 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 CEH18094.1 - 0.017 15.2 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV CTI PF06934.6 CEH18094.1 - 0.18 10.0 0.1 0.28 9.3 0.0 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) UQ_con PF00179.21 CEH18095.1 - 2.9e-45 153.1 0.0 3.3e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEH18095.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Prokaryotic E2 family B SLD3 PF08639.5 CEH18096.1 - 3e-05 22.8 16.1 0.0048 15.6 4.1 3.0 3 0 0 3 3 3 2 DNA replication regulator SLD3 SMC_N PF02463.14 CEH18097.1 - 3.2e-21 75.5 0.0 6.5e-21 74.5 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CEH18097.1 - 2.5e-15 57.3 10.9 2.5e-15 57.3 7.6 5.3 3 2 0 3 3 1 1 AAA domain AAA_21 PF13304.1 CEH18097.1 - 2.3e-06 27.8 0.1 0.00013 22.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CEH18097.1 - 0.0018 17.7 0.0 0.0042 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.4 CEH18097.1 - 0.0049 16.9 1.1 0.0049 16.9 0.7 6.0 7 0 0 7 7 7 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_19 PF13245.1 CEH18097.1 - 0.03 14.0 0.1 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_13 PF13166.1 CEH18097.1 - 0.079 11.4 48.5 0.77 8.1 0.0 4.6 3 2 0 3 3 3 0 AAA domain ABC_tran PF00005.22 CEH18097.1 - 0.11 12.8 0.0 0.11 12.8 0.0 4.4 3 2 0 3 3 2 0 ABC transporter AAA_25 PF13481.1 CEH18097.1 - 0.14 11.5 0.0 0.14 11.5 0.0 2.9 5 0 0 5 5 5 0 AAA domain Baculo_PEP_C PF04513.7 CEH18097.1 - 0.97 9.2 18.3 0.13 12.0 1.6 3.9 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATP_bind_1 PF03029.12 CEH18097.1 - 1.5 8.3 5.2 2 7.9 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 CEH18097.1 - 6.7 6.8 10.5 1.1 9.4 0.1 3.6 2 2 0 2 2 2 0 AAA domain Chitin_synth_1 PF01644.12 CEH18098.1 - 2.1e-86 287.7 0.1 3.6e-86 287.0 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CEH18098.1 - 4.7e-32 109.5 0.4 9.3e-32 108.5 0.3 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CEH18098.1 - 1.1e-24 86.7 1.0 2e-18 66.1 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CEH18098.1 - 2.4e-07 30.6 7.3 1e-06 28.6 5.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEH18098.1 - 4.6e-07 29.8 0.0 1.1e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CRIC_ras_sig PF10534.4 CEH18098.1 - 0.1 12.6 0.0 0.4 10.7 0.0 2.0 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras DUF1762 PF08574.5 CEH18099.1 - 0.00087 19.6 11.0 0.00087 19.6 7.6 4.4 2 2 2 4 4 4 2 Protein of unknown function (DUF1762) Cupin_8 PF13621.1 CEH18100.1 - 9.3e-39 133.4 0.0 1.1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CEH18100.1 - 0.0053 16.9 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C2H2 PF00096.21 CEH18101.1 - 0.0038 17.4 0.4 0.037 14.3 0.3 2.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH18101.1 - 4.1 7.9 11.1 0.24 11.8 1.6 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Abhydrolase_5 PF12695.2 CEH18102.1 - 2.5e-05 24.0 0.1 7.6e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 CEH18102.1 - 0.00014 21.4 0.1 0.00031 20.2 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 CEH18102.1 - 0.001 18.3 0.1 0.0021 17.3 0.1 1.4 1 1 0 1 1 1 1 Esterase PHB depolymerase Fungal_trans PF04082.13 CEH18104.1 - 5e-17 61.6 2.6 2.4e-16 59.4 0.3 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Glycos_transf_3 PF00591.16 CEH18106.1 - 1e-70 238.0 0.0 1.5e-69 234.2 0.0 2.1 1 1 0 2 2 2 1 Glycosyl transferase family, a/b domain ASFV_J13L PF05568.6 CEH18106.1 - 0.73 9.3 3.3 1.6 8.1 2.3 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein PDH PF02153.12 CEH18108.1 - 1.6e-20 73.0 0.0 3.3e-20 72.0 0.0 1.4 1 1 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 CEH18108.1 - 0.00031 20.6 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 CEH18108.1 - 0.0047 17.4 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.11 CEH18108.1 - 0.0086 15.5 0.1 0.028 13.8 0.1 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 CEH18108.1 - 0.022 15.1 0.0 0.059 13.7 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CEH18108.1 - 0.066 12.9 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 CEH18108.1 - 0.08 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_N PF08240.7 CEH18109.1 - 5.8e-31 106.4 2.1 1.2e-30 105.4 1.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEH18109.1 - 1e-11 44.4 0.0 1.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH18109.1 - 0.00092 20.1 0.0 0.0018 19.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 CEH18109.1 - 0.023 14.3 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 CEH18109.1 - 0.033 13.0 0.2 0.062 12.1 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 CEH18109.1 - 0.035 13.5 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MOZART1 PF12554.3 CEH18109.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated TrkA_N PF02254.13 CEH18109.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 CEH18109.1 - 0.092 12.8 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-C2H2 PF00096.21 CEH18110.1 - 1.9e-06 27.8 10.5 0.015 15.5 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 CEH18110.1 - 4.2e-06 26.5 9.0 1.1e-05 25.2 6.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 CEH18110.1 - 4.7e-05 23.4 8.0 0.042 14.1 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Allexi_40kDa PF05549.6 CEH18110.1 - 0.00059 19.2 0.2 0.00059 19.2 0.2 1.9 2 0 0 2 2 2 1 Allexivirus 40kDa protein zf-C2H2_jaz PF12171.3 CEH18110.1 - 0.0016 18.5 9.2 0.023 14.8 1.4 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Fungal_trans PF04082.13 CEH18110.1 - 0.003 16.4 0.7 0.006 15.4 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 CEH18110.1 - 0.091 13.0 12.2 0.052 13.8 1.2 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Chorismate_synt PF01264.16 CEH18111.1 - 3.6e-130 433.4 0.0 1.6e-64 217.6 0.0 2.0 1 1 1 2 2 2 2 Chorismate synthase Ribosomal_60s PF00428.14 CEH18111.1 - 0.93 9.9 6.5 2.4 8.6 4.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DAHP_synth_2 PF01474.11 CEH18112.1 - 5.6e-161 535.7 0.0 6.5e-161 535.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family FAD_binding_3 PF01494.14 CEH18114.1 - 1e-68 232.0 0.0 1.3e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEH18114.1 - 0.00055 18.9 0.3 0.0025 16.7 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CEH18114.1 - 0.0036 16.4 0.1 0.0075 15.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 CEH18114.1 - 0.0039 15.7 0.1 0.0061 15.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 CEH18114.1 - 0.0091 15.6 0.1 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 CEH18114.1 - 0.026 14.5 0.1 0.19 11.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEH18114.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CEH18114.1 - 0.06 12.4 0.7 0.11 11.5 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 CEH18114.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 CEH18114.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 CEH18114.1 - 0.11 12.4 0.1 0.38 10.8 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Epimerase PF01370.16 CEH18115.1 - 5.2e-17 62.0 0.2 1.4e-16 60.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEH18115.1 - 1.4e-15 57.8 0.0 2.9e-15 56.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CEH18115.1 - 2.3e-14 52.7 0.0 4.4e-14 51.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CEH18115.1 - 1.4e-13 50.3 0.1 3.9e-12 45.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 CEH18115.1 - 1.9e-10 40.3 0.0 7.7e-09 35.1 0.0 2.1 1 1 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 CEH18115.1 - 0.0017 18.6 0.1 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 CEH18115.1 - 0.055 13.3 0.2 0.25 11.2 0.1 2.2 2 1 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 CEH18115.1 - 0.059 12.2 0.0 0.86 8.4 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain TPP_enzyme_N PF02776.13 CEH18116.1 - 2.6e-32 111.6 0.0 5.3e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CEH18116.1 - 2.3e-17 63.0 0.1 2.2e-16 59.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CEH18116.1 - 1.2e-15 57.4 0.1 1.7e-14 53.6 0.0 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MFS_1 PF07690.11 CEH18117.1 - 1.2e-37 129.5 61.3 1.5e-34 119.3 42.2 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH18117.1 - 3.9e-07 29.0 39.8 1.2e-06 27.4 7.0 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter zf-DHHC PF01529.15 CEH18117.1 - 0.45 9.8 4.3 2.5 7.4 1.7 2.8 2 1 0 2 2 2 0 DHHC palmitoyltransferase EPSP_synthase PF00275.15 CEH18118.1 - 3e-97 325.7 0.0 4.6e-97 325.0 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CEH18118.1 - 1.9e-87 292.5 0.2 3.1e-87 291.7 0.1 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CEH18118.1 - 4.9e-53 180.0 0.0 7.8e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 CEH18118.1 - 4.6e-29 101.3 0.0 6.3e-28 97.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 CEH18118.1 - 2.5e-24 85.1 0.2 5.7e-24 83.9 0.1 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CEH18118.1 - 7.9e-11 42.2 0.0 1.8e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CEH18118.1 - 1.1e-07 31.4 1.0 2.3e-07 30.4 0.7 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 CEH18118.1 - 0.0093 16.7 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Saccharop_dh PF03435.13 CEH18118.1 - 0.081 11.8 0.8 0.24 10.3 0.0 2.1 3 0 0 3 3 3 0 Saccharopine dehydrogenase AAA_18 PF13238.1 CEH18118.1 - 0.17 12.1 0.0 0.46 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain p450 PF00067.17 CEH18120.1 - 3.9e-79 266.3 0.0 5.3e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Kri1_C PF12936.2 CEH18122.1 - 3.3e-23 81.4 0.0 3.3e-23 81.4 0.0 4.5 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 CEH18122.1 - 1.4e-20 73.4 8.1 1.4e-20 73.4 5.6 5.2 5 0 0 5 5 5 1 KRI1-like family ECH PF00378.15 CEH18123.1 - 6.9e-38 130.1 0.1 1.1e-37 129.4 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CBM_4_9 PF02018.12 CEH18125.1 - 0.0013 18.7 7.8 0.092 12.7 0.0 4.5 4 1 0 4 4 4 2 Carbohydrate binding domain EB PF01683.13 CEH18125.1 - 0.086 12.9 32.3 0.037 14.1 6.1 3.6 1 1 3 4 4 4 0 EB module PAM2 PF07145.10 CEH18129.1 - 0.013 14.9 0.1 0.052 13.0 0.0 2.1 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Imm45 PF15603.1 CEH18129.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 45 Glyco_hydro_cc PF11790.3 CEH18130.1 - 6.7e-48 163.1 5.2 8.7e-48 162.8 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_2_C PF02836.12 CEH18130.1 - 0.00023 20.1 0.4 0.00035 19.5 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain PBD PF00786.23 CEH18132.1 - 0.0026 18.1 0.0 0.0078 16.6 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Herpes_gE PF02480.11 CEH18133.1 - 0.0001 20.7 0.4 0.00019 19.8 0.1 1.6 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 CEH18133.1 - 0.0048 15.7 0.1 0.0061 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Mid2 PF04478.7 CEH18133.1 - 0.014 14.8 0.4 0.014 14.8 0.3 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF1183 PF06682.7 CEH18133.1 - 0.066 12.8 0.1 0.066 12.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) GST_N_3 PF13417.1 CEH18134.1 - 1.9e-05 24.7 0.0 5.6e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CEH18134.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.20 CEH18135.1 - 9.8e-48 162.5 0.0 1.3e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.3 CEH18135.1 - 5.7e-42 143.5 0.0 6.5e-41 140.1 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 CEH18135.1 - 3.6e-32 111.4 0.0 1.2e-31 109.6 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CEH18135.1 - 0.014 15.1 0.2 0.33 10.6 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CEH18135.1 - 0.041 12.8 0.0 0.099 11.5 0.0 1.7 1 1 0 1 1 1 0 Kinase-like SCP2 PF02036.12 CEH18136.1 - 2.4e-19 69.4 0.3 4.4e-19 68.6 0.2 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CEH18136.1 - 0.00038 20.4 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal UDPG_MGDP_dh_C PF03720.10 CEH18136.1 - 0.097 12.8 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Aa_trans PF01490.13 CEH18139.1 - 1.7e-27 95.9 31.7 2.2e-27 95.6 22.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NADH_Oxid_Nqo15 PF11497.3 CEH18139.1 - 0.078 12.7 0.0 5.7 6.6 0.0 2.3 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 NADH-u_ox-rdase PF10785.4 CEH18139.1 - 1.1 9.5 10.3 4 7.7 1.1 3.3 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit CbtB PF09489.5 CEH18139.1 - 1.2 9.1 6.9 1.2 9.1 0.2 3.6 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) p450 PF00067.17 CEH18140.1 - 1.2e-28 99.8 0.0 1.6e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.6 CEH18141.1 - 4.4e-05 22.3 0.0 0.00015 20.5 0.0 1.7 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) His_Phos_2 PF00328.17 CEH18143.1 - 1.1e-11 44.6 0.0 9.2e-11 41.6 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.17 CEH18144.1 - 5.6e-15 54.7 0.0 8.2e-15 54.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH18144.1 - 2.4e-12 46.6 0.0 3.6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH18144.1 - 2.8e-08 33.4 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEH18144.1 - 0.03 14.1 0.0 0.057 13.2 0.0 1.5 1 1 1 2 2 2 0 RNA binding motif SNF5 PF04855.7 CEH18145.1 - 7.3e-35 120.5 0.1 2e-34 119.1 0.0 1.8 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 DUF543 PF04418.7 CEH18146.1 - 8.2e-05 22.4 0.2 0.0002 21.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Phytase-like PF13449.1 CEH18147.1 - 7.9e-22 77.9 1.0 1.8e-21 76.7 0.7 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 CEH18147.1 - 0.066 12.1 0.0 2 7.3 0.0 2.2 2 0 0 2 2 2 0 SdiA-regulated Ssl1 PF04056.9 CEH18148.1 - 0.018 14.6 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Ssl1-like DAD PF02109.11 CEH18149.1 - 2.1e-35 121.1 5.3 2.3e-35 121.0 3.7 1.0 1 0 0 1 1 1 1 DAD family Ost4 PF10215.4 CEH18149.1 - 0.16 11.4 1.1 0.45 10.0 0.8 1.8 1 0 0 1 1 1 0 Oligosaccaryltransferase DUF2838 PF10998.3 CEH18150.1 - 5e-36 122.9 10.2 5e-36 122.9 7.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Pkinase PF00069.20 CEH18151.1 - 3.4e-66 223.0 0.0 4.5e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH18151.1 - 5.2e-36 124.0 0.0 7.6e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH18151.1 - 3.2e-12 46.0 0.0 4.7e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEH18151.1 - 0.026 13.6 0.0 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF964 PF06133.6 CEH18152.1 - 0.071 13.1 0.5 1.8 8.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF964) Dynactin_p22 PF07426.6 CEH18152.1 - 0.073 12.3 0.1 0.97 8.6 0.0 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 TPR_MLP1_2 PF07926.7 CEH18152.1 - 0.11 12.2 2.3 0.091 12.5 0.4 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 CEH18152.1 - 0.61 9.6 6.6 0.37 10.3 2.9 1.9 2 0 0 2 2 2 0 IncA protein TatD_DNase PF01026.16 CEH18155.1 - 5.7e-14 51.9 0.0 1.1e-12 47.6 0.0 2.1 1 1 0 1 1 1 1 TatD related DNase NYAP_N PF15439.1 CEH18155.1 - 0.081 12.0 0.3 0.12 11.5 0.2 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Sdh5 PF03937.11 CEH18156.1 - 2e-23 81.8 0.9 3.3e-23 81.1 0.6 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Mannosyl_trans2 PF04188.8 CEH18157.1 - 7.2e-21 74.6 7.4 8.4e-19 67.7 5.1 3.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) RhoGAP PF00620.22 CEH18158.1 - 1.7e-17 63.4 0.0 2.6e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Homeobox PF00046.24 CEH18161.1 - 7.3e-19 67.1 0.8 1.2e-18 66.4 0.6 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEH18161.1 - 0.016 14.8 0.1 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain PAS_9 PF13426.1 CEH18163.1 - 0.0047 17.2 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 CEH18163.1 - 0.075 12.8 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF262 PF03235.9 CEH18164.1 - 1.6e-14 54.4 0.0 7.8e-14 52.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function DUF262 LIM PF00412.17 CEH18165.1 - 1.6e-18 66.4 13.2 7.5e-11 41.9 1.5 5.1 5 0 0 5 5 5 4 LIM domain DZR PF12773.2 CEH18165.1 - 0.088 12.6 13.3 0.31 10.8 0.1 3.2 2 2 0 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 CEH18165.1 - 3.1 7.5 16.6 1.4 8.6 1.7 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Med3 PF11593.3 CEH18166.1 - 0.089 12.0 18.7 0.32 10.1 6.3 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Nucleo_P87 PF07267.6 CEH18166.1 - 0.22 10.1 1.9 0.41 9.2 1.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 tRNA-synt_1b PF00579.20 CEH18167.1 - 6.5e-60 202.7 0.0 9.3e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 CEH18167.1 - 0.00053 19.3 0.0 0.0016 17.8 0.0 1.8 1 0 0 1 1 1 1 S4 domain Peptidase_S10 PF00450.17 CEH18170.1 - 1.5e-76 258.2 0.0 1.9e-76 257.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.16 CEH18170.1 - 0.0043 16.2 0.1 0.0072 15.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Bot1p PF12298.3 CEH18171.1 - 0.035 14.0 0.3 0.043 13.7 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein DCP2 PF05026.8 CEH18173.1 - 2.3e-31 107.5 0.0 6e-31 106.1 0.0 1.7 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 CEH18173.1 - 1.4e-15 57.1 0.0 2.5e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Telomere_Sde2 PF13019.1 CEH18174.1 - 3.5e-38 130.8 1.4 3.5e-38 130.8 1.0 1.7 2 0 0 2 2 2 1 Telomere stability and silencing PSII_Pbs27 PF13326.1 CEH18174.1 - 0.013 15.4 2.5 0.015 15.2 0.2 2.0 2 0 0 2 2 2 0 Photosystem II Pbs27 ATP_bind_1 PF03029.12 CEH18175.1 - 3.9e-80 268.8 0.0 4.6e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CEH18175.1 - 4.2e-06 27.5 0.1 7.4e-06 26.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 CEH18175.1 - 1.9e-05 24.1 0.0 4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 CEH18175.1 - 5.6e-05 23.1 0.3 0.00025 21.0 0.0 2.1 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 CEH18175.1 - 0.00017 21.7 0.0 0.00057 20.0 0.0 2.0 1 1 0 2 2 2 1 AAA domain MobB PF03205.9 CEH18175.1 - 0.00022 20.9 0.0 0.00065 19.4 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 CEH18175.1 - 0.00096 18.1 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 CEH18175.1 - 0.00097 18.6 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CEH18175.1 - 0.0011 19.3 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CEH18175.1 - 0.0011 18.5 0.1 0.039 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CEH18175.1 - 0.0016 17.8 0.2 0.017 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CEH18175.1 - 0.002 17.6 0.2 1 8.7 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 CEH18175.1 - 0.0021 17.5 0.1 0.13 11.6 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CEH18175.1 - 0.0023 16.7 0.0 0.0038 16.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 CEH18175.1 - 0.0027 17.1 0.0 0.0067 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 CEH18175.1 - 0.0027 17.6 0.0 0.0057 16.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_35 PF14516.1 CEH18175.1 - 0.0058 15.3 0.0 1.2 7.6 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_14 PF13173.1 CEH18175.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CEH18175.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 CEH18175.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 CEH18175.1 - 0.016 15.0 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CEH18175.1 - 0.018 14.7 0.0 0.13 12.0 0.0 2.3 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CEH18175.1 - 0.02 15.0 0.0 0.066 13.3 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA PF00004.24 CEH18175.1 - 0.022 14.9 0.1 0.079 13.1 0.0 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 CEH18175.1 - 0.024 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.13 CEH18175.1 - 0.026 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CEH18175.1 - 0.026 14.2 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 CEH18175.1 - 0.027 14.0 0.0 0.069 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CEH18175.1 - 0.029 13.7 0.0 0.077 12.4 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 CEH18175.1 - 0.03 13.8 0.0 0.089 12.2 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.17 CEH18175.1 - 0.059 12.8 0.0 0.14 11.6 0.0 1.5 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain DUF2075 PF09848.4 CEH18175.1 - 0.062 12.2 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CobU PF02283.11 CEH18175.1 - 0.07 12.5 0.1 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF258 PF03193.11 CEH18175.1 - 0.097 11.8 0.1 0.64 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DAP3 PF10236.4 CEH18175.1 - 0.12 11.2 0.1 0.29 10.0 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.8 CEH18175.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KH_1 PF00013.24 CEH18177.1 - 4.1e-76 250.5 31.4 5.5e-13 48.3 0.5 13.0 13 2 0 13 13 13 10 KH domain KH_3 PF13014.1 CEH18177.1 - 1.7e-50 167.9 23.4 1.8e-10 40.2 0.0 12.5 12 0 0 12 12 12 9 KH domain KH_2 PF07650.12 CEH18177.1 - 4.2e-14 51.8 16.5 0.00048 19.6 0.1 8.6 8 1 0 9 9 9 5 KH domain KH_4 PF13083.1 CEH18177.1 - 1.4e-08 34.2 2.1 0.1 12.2 0.0 6.7 6 0 0 6 6 6 3 KH domain SLS PF14611.1 CEH18177.1 - 9.6e-06 25.1 10.2 1.3 8.4 0.0 6.8 6 1 1 7 7 7 2 Mitochondrial inner-membrane-bound regulator YbbR PF07949.7 CEH18177.1 - 0.0035 17.4 22.1 1.5 8.9 0.0 7.3 9 0 0 9 9 9 3 YbbR-like protein Calreticulin PF00262.13 CEH18178.1 - 7.4e-154 511.8 9.0 9.9e-154 511.4 6.2 1.1 1 0 0 1 1 1 1 Calreticulin family Arm PF00514.18 CEH18179.1 - 1.1e-67 221.6 28.0 8.5e-12 44.4 0.0 11.3 10 1 1 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CEH18179.1 - 6.6e-22 77.5 14.3 0.00031 20.9 0.1 7.4 2 2 5 7 7 7 7 HEAT repeats HEAT PF02985.17 CEH18179.1 - 1.8e-14 52.4 20.9 0.59 10.3 0.0 10.1 11 0 0 11 11 10 6 HEAT repeat HEAT_EZ PF13513.1 CEH18179.1 - 7.3e-12 45.4 20.1 0.025 15.0 0.1 9.2 8 4 3 11 11 10 5 HEAT-like repeat Arm_2 PF04826.8 CEH18179.1 - 6.1e-11 41.9 5.7 0.00053 19.1 0.1 3.5 1 1 1 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 CEH18179.1 - 7e-10 37.8 7.9 1.9e-07 29.7 0.1 2.9 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.7 CEH18179.1 - 2e-09 35.9 0.1 4.2e-09 34.9 0.0 1.3 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 CEH18179.1 - 3.7e-07 29.5 2.6 0.0028 16.8 0.6 4.4 1 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 CEH18179.1 - 0.0074 16.1 2.7 6.6 6.6 0.1 4.3 2 1 3 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 CEH18179.1 - 0.085 13.3 10.6 92 3.9 0.0 7.4 9 0 0 9 9 7 0 PBS lyase HEAT-like repeat DUF3361 PF11841.3 CEH18179.1 - 0.18 11.4 3.9 4.8 6.8 0.0 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF3361) SH3_1 PF00018.23 CEH18180.1 - 6.6e-23 79.8 0.0 2.1e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CEH18180.1 - 1.3e-16 59.9 0.0 1.8e-08 33.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CEH18180.1 - 7.3e-14 51.0 0.0 5e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 CEH18180.1 - 7.8e-07 28.8 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 CEH18180.1 - 0.0085 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 PB1 domain S4 PF01479.20 CEH18182.1 - 4.5e-11 41.9 0.0 7.7e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain Sec62 PF03839.11 CEH18182.1 - 0.36 10.1 1.6 0.56 9.5 1.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 S-AdoMet_synt_C PF02773.11 CEH18183.1 - 1.7e-74 248.0 0.5 3.2e-74 247.1 0.4 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CEH18183.1 - 2.3e-48 163.0 0.0 4.3e-48 162.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CEH18183.1 - 4e-43 145.7 0.1 4e-43 145.7 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.12 CEH18183.1 - 0.057 12.4 0.0 3.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Amidinotransferase adh_short PF00106.20 CEH18184.1 - 3.8e-13 49.6 0.0 7.4e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH18184.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CEH18184.1 - 0.0024 17.9 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 CEH18184.1 - 0.0091 15.7 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 CEH18184.1 - 0.034 13.9 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase USP7_ICP0_bdg PF12436.3 CEH18189.1 - 9.6e-86 287.0 0.8 1.7e-85 286.2 0.5 1.4 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 CEH18189.1 - 4.6e-66 222.3 0.9 3.8e-64 216.0 0.1 2.7 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 CEH18189.1 - 9.1e-57 192.2 0.0 1.4e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEH18189.1 - 2.4e-32 112.5 0.0 3.7e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 CEH18189.1 - 3.8e-08 33.5 0.1 2.5e-07 30.9 0.1 2.4 1 1 0 1 1 1 1 MATH domain F-box-like PF12937.2 CEH18189.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 0 F-box-like Rad60-SLD PF11976.3 CEH18189.1 - 1.3 8.8 4.9 0.89 9.2 0.0 3.4 5 1 0 5 5 5 0 Ubiquitin-2 like Rad60 SUMO-like SIR2 PF02146.12 CEH18190.1 - 2.1e-21 76.4 0.0 3.3e-20 72.5 0.0 2.3 2 0 0 2 2 2 1 Sir2 family Macro PF01661.16 CEH18191.1 - 2.5e-40 137.0 0.0 5.4e-40 135.9 0.1 1.5 2 0 0 2 2 2 1 Macro domain COOH-NH2_lig PF14395.1 CEH18191.1 - 0.097 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 E1-E2_ATPase PF00122.15 CEH18192.1 - 3e-66 222.7 6.8 2.2e-65 219.9 0.3 3.5 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CEH18192.1 - 6.1e-23 82.3 0.5 1.3e-22 81.3 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEH18192.1 - 3.7e-13 50.0 0.0 6.6e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEH18192.1 - 6.6e-11 41.5 0.0 1.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CEH18192.1 - 0.0011 18.6 0.1 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEH18192.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit YrvL PF14184.1 CEH18192.1 - 1.9 8.3 11.9 0.038 13.8 2.8 2.3 2 0 0 2 2 2 0 Regulatory protein YrvL Glyoxalase_2 PF12681.2 CEH18193.1 - 7e-12 45.9 0.0 1.7e-11 44.6 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 CEH18193.1 - 6.3e-06 26.1 0.0 2.8e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Adeno_IVa2 PF02456.10 CEH18193.1 - 0.019 13.6 0.0 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein FAD_binding_7 PF03441.9 CEH18194.1 - 4.4e-88 295.0 0.6 7.7e-88 294.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CEH18194.1 - 4.6e-33 114.2 0.1 8.4e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 CEH18194.1 - 0.15 12.2 4.2 0.51 10.5 0.1 2.7 2 1 0 2 2 2 0 Universal stress protein family Nnf1 PF03980.9 CEH18196.1 - 2.4e-05 24.2 1.2 2.4e-05 24.2 0.8 1.9 2 0 0 2 2 2 1 Nnf1 DUF2779 PF11074.3 CEH18196.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) GrpE PF01025.14 CEH18196.1 - 0.19 11.2 7.0 4.5 6.7 3.3 2.7 1 1 1 2 2 2 0 GrpE Methyltransf_26 PF13659.1 CEH18197.1 - 1.5e-13 50.7 0.1 1.3e-11 44.4 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH18197.1 - 1.4e-06 28.7 0.2 4.2e-06 27.3 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH18197.1 - 1.5e-06 27.8 0.1 7.6e-06 25.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH18197.1 - 0.00013 22.3 0.1 0.00032 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEH18197.1 - 0.00025 20.4 0.3 0.0086 15.4 0.2 2.6 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 CEH18197.1 - 0.0052 16.3 0.0 0.062 12.8 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 CEH18197.1 - 0.0055 16.4 0.3 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.11 CEH18197.1 - 0.051 12.6 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 N-6 DNA Methylase Sec66 PF09802.4 CEH18198.1 - 2.7e-21 75.8 0.2 4.3e-21 75.1 0.0 1.4 2 0 0 2 2 2 1 Preprotein translocase subunit Sec66 TrbI PF03743.9 CEH18198.1 - 0.068 12.6 0.1 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein PAT1 PF09770.4 CEH18198.1 - 0.97 7.5 13.0 1 7.4 9.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CEH18198.1 - 2.9 7.7 9.6 3.2 7.5 6.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acyl-CoA_dh_1 PF00441.19 CEH18200.1 - 2e-27 96.1 0.8 4.4e-27 95.0 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEH18200.1 - 1.6e-23 81.9 0.1 1e-13 50.5 0.0 2.8 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CEH18200.1 - 1.8e-14 54.1 0.9 3.6e-14 53.1 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CEH18200.1 - 1.4e-09 38.5 0.0 2.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain BPL_LplA_LipB PF03099.14 CEH18200.1 - 0.11 12.5 0.0 7.9 6.5 0.0 2.5 1 1 1 2 2 2 0 Biotin/lipoate A/B protein ligase family EBP PF05241.7 CEH18201.1 - 0.00051 19.1 8.2 0.0021 17.1 5.7 1.8 1 1 0 1 1 1 1 Emopamil binding protein DUF2628 PF10947.3 CEH18201.1 - 0.72 9.6 7.2 4.5 7.1 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2628) Actin PF00022.14 CEH18202.1 - 6.2e-115 383.7 0.0 7.8e-115 383.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CEH18202.1 - 0.0047 15.5 0.0 0.023 13.3 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein RCR PF12273.3 CEH18203.1 - 0.0038 17.7 7.2 0.0038 17.7 5.0 2.5 3 1 0 3 3 3 1 Chitin synthesis regulation, resistance to Congo red Choline_transpo PF04515.7 CEH18203.1 - 0.039 12.7 4.9 0.069 11.8 3.4 1.5 1 1 0 1 1 1 0 Plasma-membrane choline transporter RabGAP-TBC PF00566.13 CEH18204.1 - 1.8e-48 164.8 0.0 2.3e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.23 CEH18204.1 - 0.0077 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEH18204.1 - 0.13 11.7 0.1 0.48 9.9 0.0 1.9 2 0 0 2 2 2 0 Variant SH3 domain DUF2256 PF10013.4 CEH18206.1 - 4.6e-11 42.2 6.0 7.9e-11 41.5 4.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-FCS PF06467.9 CEH18206.1 - 0.15 11.7 4.4 0.51 10.0 3.0 1.9 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Pkinase PF00069.20 CEH18207.1 - 7.7e-51 172.7 0.0 2.5e-44 151.3 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH18207.1 - 6.5e-24 84.3 0.0 4.2e-19 68.6 0.0 3.5 4 0 0 4 4 4 3 Protein tyrosine kinase Kinase-like PF14531.1 CEH18207.1 - 5.8e-05 22.1 0.0 0.26 10.1 0.0 2.7 3 0 0 3 3 3 2 Kinase-like TauD PF02668.11 CEH18210.1 - 3.6e-47 161.2 0.8 4.9e-47 160.7 0.6 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family bZIP_1 PF00170.16 CEH18212.1 - 1e-12 47.8 5.3 1.5e-12 47.2 3.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor Aft1_HRA PF11786.3 CEH18212.1 - 3.5e-12 46.4 13.7 3.5e-12 46.4 9.5 3.2 3 1 0 3 3 3 1 Aft1 HRA domain bZIP_2 PF07716.10 CEH18212.1 - 6.8e-07 29.0 11.1 7.8e-07 28.8 7.2 1.4 1 1 0 1 1 1 1 Basic region leucine zipper DUF1192 PF06698.6 CEH18212.1 - 0.094 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) bZIP_Maf PF03131.12 CEH18212.1 - 0.18 12.1 6.2 0.28 11.5 4.3 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Phlebovirus_NSM PF07246.6 CEH18212.1 - 0.41 9.7 1.5 0.56 9.3 1.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF2968 PF11180.3 CEH18212.1 - 0.53 9.6 6.6 0.73 9.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Chitin_synth_1 PF01644.12 CEH18213.1 - 8.7e-67 223.9 0.0 1.3e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CEH18213.1 - 2.1e-26 91.4 0.0 3.7e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CEH18213.1 - 2.1e-25 89.1 0.0 1.1e-19 70.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CEH18213.1 - 4.2e-13 49.4 2.1 1.4e-12 47.7 1.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEH18213.1 - 6.2e-08 32.7 0.0 1.4e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 zf-HIT PF04438.11 CEH18214.1 - 1.4e-07 30.9 7.3 2.2e-07 30.3 5.1 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF2514 PF10721.4 CEH18215.1 - 0.012 15.3 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF4330 PF14221.1 CEH18215.1 - 0.044 13.6 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Tetraspannin PF00335.15 CEH18215.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.0 1 0 0 1 1 1 0 Tetraspanin family DivIC PF04977.10 CEH18215.1 - 8.9 5.8 6.5 18 4.8 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator PP2C PF00481.16 CEH18216.1 - 7e-50 169.8 0.5 1.7e-49 168.5 0.4 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 CEH18216.1 - 3.6e-47 157.3 67.2 8.8e-07 28.4 1.6 14.2 8 3 8 16 16 16 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEH18216.1 - 2.6e-40 135.9 65.6 8.7e-08 31.8 0.2 10.3 6 4 5 11 11 11 9 Leucine rich repeat Guanylate_cyc PF00211.15 CEH18216.1 - 1.8e-23 82.8 0.0 3.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 CEH18216.1 - 6.7e-23 77.1 60.1 0.12 12.5 0.1 19.0 19 1 0 19 19 19 11 Leucine Rich Repeat LRR_7 PF13504.1 CEH18216.1 - 1.3e-07 30.6 58.3 0.99 9.8 0.7 17.1 20 0 0 20 20 20 3 Leucine rich repeat LRR_6 PF13516.1 CEH18216.1 - 4.2e-06 26.2 42.9 14 6.1 0.0 15.9 16 0 0 16 16 16 1 Leucine Rich repeat LRR_5 PF13306.1 CEH18216.1 - 0.0037 16.9 5.7 3.1 7.5 0.2 4.0 1 1 1 3 3 3 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 CEH18216.1 - 0.0049 16.4 13.7 0.29 10.6 0.2 4.4 2 1 1 4 4 4 2 Leucine-rich repeat ENTH PF01417.15 CEH18217.1 - 4.2e-48 162.3 0.5 7.5e-48 161.5 0.1 1.6 2 0 0 2 2 2 1 ENTH domain UIM PF02809.15 CEH18217.1 - 6.5e-05 22.1 6.4 0.0025 17.2 1.0 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.11 CEH18217.1 - 0.0027 16.4 0.1 0.0048 15.6 0.1 1.6 1 1 0 1 1 1 1 ANTH domain DUF1635 PF07795.6 CEH18217.1 - 0.3 10.4 0.0 0.3 10.4 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1635) LMBR1 PF04791.11 CEH18217.1 - 1 7.8 4.6 1.5 7.3 3.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Paf1 PF03985.8 CEH18218.1 - 5.3e-37 127.6 7.9 6.1e-35 120.8 5.5 2.3 1 1 0 1 1 1 1 Paf1 DUF3135 PF11333.3 CEH18218.1 - 0.95 9.6 5.6 8.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) ATG13 PF10033.4 CEH18219.1 - 3.9e-30 105.0 0.0 5.8e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 PIN_4 PF13638.1 CEH18220.1 - 1.8e-19 70.1 0.1 4.4e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.4 CEH18220.1 - 5.6e-10 38.8 0.0 1.4e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain 2_5_RNA_ligase2 PF13563.1 CEH18222.1 - 3.9e-16 59.1 3.0 4.5e-07 29.7 0.0 3.0 2 1 0 2 2 2 2 2'-5' RNA ligase superfamily WLM PF08325.5 CEH18225.1 - 1.2e-45 155.6 0.2 3.4e-45 154.1 0.0 1.9 2 1 0 2 2 2 1 WLM domain zf-RanBP PF00641.13 CEH18225.1 - 0.00033 19.7 7.4 0.00086 18.3 5.1 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 CEH18225.1 - 0.0005 19.9 1.2 0.0014 18.5 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 Hamartin PF04388.7 CEH18226.1 - 7.7e-10 38.0 25.5 1.1e-08 34.3 12.8 4.0 2 1 0 2 2 2 1 Hamartin protein LUC7 PF03194.10 CEH18227.1 - 1.7e-64 217.7 3.8 1.7e-64 217.7 2.6 2.0 2 1 0 2 2 2 1 LUC7 N_terminus PRP38_assoc PF12871.2 CEH18227.1 - 0.012 16.0 21.3 0.012 16.0 14.8 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TORC_N PF12884.2 CEH18227.1 - 0.021 15.3 0.5 0.044 14.3 0.4 1.5 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus PPR PF01535.15 CEH18229.1 - 5.6e-10 38.5 0.3 0.045 13.7 0.0 5.5 5 0 0 5 5 5 3 PPR repeat PPR_2 PF13041.1 CEH18229.1 - 1.1e-08 34.9 0.0 0.06 13.3 0.0 6.0 8 0 0 8 8 8 2 PPR repeat family PPR_3 PF13812.1 CEH18229.1 - 3.8e-06 26.7 10.4 0.027 14.7 0.0 7.4 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 CEH18229.1 - 0.0055 16.1 0.1 0.66 9.5 0.0 3.4 3 0 0 3 3 3 1 PPR repeat ATP-synt PF00231.14 CEH18230.1 - 3.1e-50 171.1 9.1 1.6e-37 129.4 1.5 2.1 1 1 1 2 2 2 2 ATP synthase MFS_1 PF07690.11 CEH18231.1 - 3.3e-16 58.9 48.0 8.6e-16 57.5 24.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily RA PF00788.18 CEH18232.1 - 1e-15 57.9 0.0 1.1e-10 41.8 0.0 3.3 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 CEH18232.1 - 1.1e-07 31.0 0.0 4.1e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CEH18232.1 - 0.0023 17.4 0.2 0.0092 15.5 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain DUF155 PF02582.9 CEH18233.1 - 3.9e-50 170.1 0.0 5.5e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ADH_zinc_N PF00107.21 CEH18234.1 - 1.7e-24 85.8 0.1 3.3e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH18234.1 - 6.1e-09 36.8 0.0 2.4e-08 34.9 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 CEH18234.1 - 8.7e-06 25.0 0.3 0.046 12.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2855) Glyco_transf_28 PF03033.15 CEH18235.1 - 0.00024 20.8 0.0 0.00078 19.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 CEH18235.1 - 0.0095 14.5 0.0 0.072 11.6 0.1 1.9 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase IRF-3 PF10401.4 CEH18235.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-regulatory factor 3 p450 PF00067.17 CEH18238.1 - 8.8e-54 182.7 0.0 4.1e-42 144.2 0.0 3.6 3 1 0 3 3 3 3 Cytochrome P450 AhpC-TSA_2 PF13911.1 CEH18239.1 - 8.6e-10 38.5 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Lon_C PF05362.8 CEH18241.1 - 5.4e-38 130.3 0.1 6.3e-38 130.1 0.1 1.1 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.1 CEH18241.1 - 2.4e-06 27.0 0.0 3.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Birna_VP4 PF01768.11 CEH18241.1 - 0.003 16.6 0.1 0.0038 16.3 0.0 1.1 1 0 0 1 1 1 1 Birnavirus VP4 protein TRI12 PF06609.8 CEH18241.1 - 0.018 13.2 0.0 0.021 13.0 0.0 1.0 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Sporozoite_P67 PF05642.6 CEH18242.1 - 0.55 8.0 10.7 0.53 8.0 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Post_transc_reg PF13797.1 CEH18243.1 - 0.024 14.2 0.2 0.03 13.9 0.1 1.1 1 0 0 1 1 1 0 Post-transcriptional regulator PAF-AH_p_II PF03403.8 CEH18244.1 - 6.1e-45 153.1 0.0 5.7e-44 149.9 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 CEH18244.1 - 1.9e-11 43.9 0.2 5.3e-11 42.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH18244.1 - 6.9e-07 29.3 1.1 1.8e-06 27.9 0.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CEH18244.1 - 0.0009 18.2 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 CEH18244.1 - 0.0089 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Sod_Fe_C PF02777.13 CEH18245.1 - 2.5e-16 59.4 0.0 1.3e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Carboxyl_trans PF01039.17 CEH18247.1 - 4.8e-167 556.2 2.4 4.2e-106 355.2 0.0 2.0 1 1 1 2 2 2 2 Carboxyl transferase domain MdcE PF06833.6 CEH18247.1 - 0.00027 20.2 0.3 0.16 11.1 0.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) S-methyl_trans PF02574.11 CEH18248.1 - 2.5e-34 118.9 0.0 1.6e-21 76.9 0.0 3.1 2 1 1 3 3 3 3 Homocysteine S-methyltransferase EBP PF05241.7 CEH18249.1 - 6.6e-57 191.6 8.5 8.7e-57 191.2 5.9 1.1 1 0 0 1 1 1 1 Emopamil binding protein ADH_N PF08240.7 CEH18250.1 - 7.7e-28 96.4 0.2 1.4e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEH18250.1 - 5.7e-24 84.1 0.1 1.1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH18250.1 - 0.00014 22.7 0.1 0.0003 21.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 CEH18250.1 - 0.03 13.6 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 CEH18250.1 - 0.053 13.1 0.1 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fe_hyd_lg_C PF02906.9 CEH18251.1 - 7.6e-61 205.8 0.0 2.7e-60 204.0 0.0 2.0 2 1 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain BTB PF00651.26 CEH18252.1 - 0.033 14.1 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Scramblase PF03803.10 CEH18253.1 - 5e-51 172.8 0.0 6.7e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Scramblase DAO PF01266.19 CEH18254.1 - 5.3e-43 147.2 1.1 7.6e-43 146.7 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CEH18254.1 - 1.3e-05 25.3 0.0 0.063 13.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEH18254.1 - 7.5e-05 22.5 0.5 0.00028 20.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CEH18254.1 - 0.0012 18.8 0.1 0.004 17.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain APG12 PF04110.8 CEH18255.1 - 4.3e-30 103.7 0.0 5.1e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 CEH18255.1 - 0.0033 17.3 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Acyltransferase PF01553.16 CEH18256.1 - 5.7e-34 116.4 0.0 9.6e-34 115.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Ribonuclease_3 PF00636.21 CEH18257.1 - 2.2e-33 115.0 0.0 2.3e-18 66.6 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.9 CEH18257.1 - 4.6e-18 64.7 0.0 2e-17 62.7 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.24 CEH18257.1 - 2.5e-14 53.1 0.0 4.7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribonucleas_3_3 PF14622.1 CEH18257.1 - 5.2e-14 52.3 0.0 9.2e-09 35.3 0.0 3.3 2 1 0 2 2 2 2 Ribonuclease-III-like ResIII PF04851.10 CEH18257.1 - 4e-11 43.0 0.0 7.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CEH18257.1 - 1.7e-10 40.6 0.0 1.2e-09 37.8 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain dsrm PF00035.20 CEH18257.1 - 0.039 14.5 0.0 7.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Double-stranded RNA binding motif Strumpellin PF10266.4 CEH18257.1 - 0.044 11.1 0.0 0.067 10.6 0.0 1.1 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin AAA_26 PF13500.1 CEH18257.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 CEH18257.1 - 0.19 10.5 0.0 0.34 9.6 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain PhoH PF02562.11 CEH18257.1 - 0.27 10.4 0.0 1 8.5 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Fork_head PF00250.13 CEH18258.1 - 2e-11 43.7 0.0 3.6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CEH18258.1 - 0.0029 17.6 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Apt1 PF10351.4 CEH18258.1 - 3.3 6.4 7.2 0.071 11.9 0.2 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ytp1 PF10355.4 CEH18259.1 - 5.9e-94 314.2 0.2 9.7e-94 313.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CEH18259.1 - 1.3e-20 72.8 1.0 1.3e-20 72.8 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Flavi_NS4B PF01349.12 CEH18259.1 - 0.045 12.6 2.1 0.08 11.8 1.5 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B Herpes_US9 PF06072.6 CEH18259.1 - 0.34 10.7 2.2 1.4 8.8 0.1 2.9 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 adh_short PF00106.20 CEH18260.1 - 4.4e-09 36.4 6.2 1.9e-06 27.9 0.3 2.6 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 CEH18260.1 - 0.00028 20.6 0.1 0.00062 19.4 0.1 1.6 1 1 0 1 1 1 1 KR domain Tau95 PF09734.4 CEH18261.1 - 0.12 11.7 1.9 0.15 11.4 1.3 1.0 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit Ribosomal_S3Ae PF01015.13 CEH18262.1 - 1.2e-81 272.7 1.4 1.4e-81 272.4 1.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 CEH18262.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region RRM_1 PF00076.17 CEH18263.1 - 3.7e-14 52.0 0.0 6.2e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH18263.1 - 3.3e-10 39.7 0.0 5.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CEH18263.1 - 2.7e-08 34.1 1.5 2.7e-08 34.1 1.0 2.5 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 CEH18263.1 - 6.7e-08 32.2 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage-tail_3 PF13550.1 CEH18263.1 - 0.0043 16.8 0.4 0.0067 16.2 0.3 1.2 1 0 0 1 1 1 1 Putative phage tail protein MSP1_C PF07462.6 CEH18263.1 - 0.023 13.0 1.0 0.03 12.7 0.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus MFS_1 PF07690.11 CEH18265.1 - 1e-30 106.6 14.0 1e-30 106.6 9.7 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH18265.1 - 1.7e-11 43.3 0.6 1.7e-11 43.3 0.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter V_ATPase_I PF01496.14 CEH18265.1 - 0.18 9.6 0.0 0.31 8.8 0.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PsbY PF06298.6 CEH18267.1 - 0.0061 16.0 0.6 0.0097 15.4 0.4 1.2 1 0 0 1 1 1 1 Photosystem II protein Y (PsbY) Diphthamide_syn PF01866.12 CEH18268.1 - 3.4e-54 184.1 0.0 1.1e-26 93.8 0.0 3.1 3 0 0 3 3 3 3 Putative diphthamide synthesis protein WD40 PF00400.27 CEH18269.1 - 8.3e-19 66.6 0.7 3.1e-06 26.8 0.1 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat GA PF01468.12 CEH18270.1 - 0.059 13.5 0.2 0.059 13.5 0.1 2.0 2 0 0 2 2 2 0 GA module PhageMin_Tail PF10145.4 CEH18270.1 - 0.14 11.7 3.4 0.17 11.4 0.1 2.1 2 0 0 2 2 2 0 Phage-related minor tail protein GSK-3_bind PF05350.7 CEH18271.1 - 0.13 11.6 0.5 0.13 11.6 0.3 1.0 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Histidinol_dh PF00815.15 CEH18272.1 - 8.9e-161 535.1 0.3 2.2e-143 477.8 1.4 2.1 1 1 1 2 2 2 2 Histidinol dehydrogenase PRA-CH PF01502.13 CEH18272.1 - 3e-23 81.2 0.0 5.7e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 CEH18272.1 - 1.9e-10 40.8 0.1 6.8e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 CEH18272.1 - 0.0083 16.0 1.4 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain Peptidase_S28 PF05577.7 CEH18274.1 - 4.7e-42 144.0 0.0 1.8e-41 142.1 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CEH18274.1 - 0.00019 21.3 0.0 0.00052 19.9 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Actin PF00022.14 CEH18275.1 - 9e-110 366.7 0.0 1.1e-109 366.5 0.0 1.1 1 0 0 1 1 1 1 Actin XPG_N PF00752.12 CEH18276.1 - 2.6e-31 107.8 0.0 6.9e-31 106.5 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CEH18276.1 - 1.6e-25 88.9 0.0 3.7e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 CEH18276.1 - 2e-05 24.2 0.1 7.2e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 XPG domain containing ADH_zinc_N PF00107.21 CEH18277.1 - 4.5e-10 39.1 0.0 8.1e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH18277.1 - 0.0003 20.5 0.0 0.0013 18.5 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain GHMP_kinases_C PF08544.8 CEH18277.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 GHMP kinases C terminal DLH PF01738.13 CEH18278.1 - 5.8e-07 29.0 0.0 2.7e-05 23.5 0.0 2.0 1 1 1 2 2 2 2 Dienelactone hydrolase family B56 PF01603.15 CEH18280.1 - 3.6e-44 151.0 1.6 3.9e-44 150.8 1.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.15 CEH18281.1 - 1.4e-104 349.9 6.4 4.6e-69 233.0 0.2 2.1 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) EOS1 PF12326.3 CEH18282.1 - 7.9e-19 67.7 0.0 1.6e-18 66.7 0.0 1.5 1 1 0 1 1 1 1 N-glycosylation protein Usp PF00582.21 CEH18283.1 - 1.4e-13 51.1 0.3 2.4e-13 50.4 0.2 1.4 1 0 0 1 1 1 1 Universal stress protein family RasGAP_C PF03836.10 CEH18285.1 - 4.9e-43 146.2 5.0 4.9e-43 146.2 3.5 2.7 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 CEH18285.1 - 7.7e-41 139.9 0.2 3.4e-40 137.8 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 CEH18285.1 - 5.3e-24 81.5 29.8 0.0087 15.6 0.2 10.0 9 0 0 9 9 9 9 IQ calmodulin-binding motif CH PF00307.26 CEH18285.1 - 3.8e-11 42.9 0.0 9.7e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain LysM PF01476.15 CEH18286.1 - 0.0035 17.2 0.1 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 LysM domain Baculo_IE-1 PF05290.6 CEH18286.1 - 0.06 13.0 0.8 0.1 12.2 0.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) SNF2_N PF00176.18 CEH18287.1 - 4.8e-84 281.6 0.1 9.2e-84 280.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CEH18287.1 - 2.2e-36 124.1 0.3 2.2e-36 124.1 0.2 2.3 3 0 0 3 3 2 1 SLIDE HAND PF09110.6 CEH18287.1 - 8.9e-28 96.9 5.3 8.9e-28 96.9 3.7 3.8 3 1 0 3 3 2 1 HAND Helicase_C PF00271.26 CEH18287.1 - 3.9e-15 55.4 0.0 1.2e-13 50.6 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CEH18287.1 - 2.7e-08 32.9 0.0 6.6e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CEH18287.1 - 6.5e-08 32.6 0.0 6.5e-08 32.6 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CEH18287.1 - 2.1e-06 27.3 0.0 7.2e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 CEH18287.1 - 6e-05 23.0 0.4 0.045 13.8 0.0 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain DBINO PF13892.1 CEH18287.1 - 0.0021 18.1 5.4 0.0021 18.1 3.8 3.2 3 1 0 3 3 2 1 DNA-binding domain DEAD_2 PF06733.10 CEH18287.1 - 0.038 13.3 0.0 0.095 12.0 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 CEH18287.1 - 0.068 13.0 5.0 0.074 12.9 0.0 3.5 3 1 1 4 4 4 0 AAA domain AAA_22 PF13401.1 CEH18287.1 - 0.076 13.1 0.5 0.45 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 CEH18287.1 - 0.68 9.4 0.0 0.68 9.4 0.0 3.9 3 1 0 3 3 3 0 AAA domain Cyclin_N PF00134.18 CEH18289.1 - 2.4e-45 153.1 0.3 2.7e-42 143.3 0.2 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CEH18289.1 - 6.4e-26 90.6 0.0 1.5e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Romo1 PF10247.4 CEH18291.1 - 1.6e-21 76.2 13.8 2.2e-21 75.8 9.6 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DHH PF01368.15 CEH18292.1 - 6.9e-09 35.4 0.0 3.5e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 DHH family DHHA2 PF02833.9 CEH18292.1 - 0.00013 22.1 0.0 0.00064 19.9 0.0 2.0 2 0 0 2 2 2 1 DHHA2 domain polyprenyl_synt PF00348.12 CEH18293.1 - 7e-40 136.5 0.1 1.1e-34 119.4 0.0 3.8 2 1 0 2 2 2 2 Polyprenyl synthetase NUDIX PF00293.23 CEH18294.1 - 5.4e-15 55.2 0.2 4.2e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Abhydrolase_5 PF12695.2 CEH18295.1 - 8.6e-06 25.5 0.0 1.6e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CEH18295.1 - 0.007 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CEH18295.1 - 0.015 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Pkinase PF00069.20 CEH18298.1 - 7.7e-50 169.4 0.0 1.2e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH18298.1 - 2.1e-44 151.5 0.0 3e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.22 CEH18298.1 - 0.00024 20.5 0.1 0.00064 19.1 0.1 1.8 1 0 0 1 1 1 1 SAP domain RIO1 PF01163.17 CEH18298.1 - 0.2 11.0 0.1 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Peptidase_M20 PF01546.23 CEH18299.1 - 1e-31 109.9 0.0 1.8e-31 109.1 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CEH18299.1 - 6.1e-12 45.2 0.0 1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Ras PF00071.17 CEH18300.1 - 1.6e-52 177.1 0.0 2e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH18300.1 - 1.7e-13 51.0 0.0 2.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH18300.1 - 8.5e-12 44.6 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 CEH18300.1 - 7e-07 28.6 0.1 1e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 CEH18300.1 - 3.2e-05 23.8 0.0 5.2e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEH18300.1 - 0.00019 20.8 0.0 0.00088 18.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CEH18300.1 - 0.017 14.2 0.1 0.024 13.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 CEH18300.1 - 0.067 12.4 0.0 0.21 10.8 0.0 1.7 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CEH18300.1 - 0.12 12.5 0.0 0.47 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Herpes_BMRF2 PF04633.7 CEH18301.1 - 2.7 6.8 24.7 0.014 14.4 4.5 2.1 2 0 0 2 2 2 0 Herpesvirus BMRF2 protein Pex16 PF08610.5 CEH18302.1 - 6.2e-76 255.5 0.0 5.2e-74 249.2 0.0 2.3 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) E1_dh PF00676.15 CEH18303.1 - 3.6e-88 295.1 0.0 4.4e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 CEH18303.1 - 9.5e-07 27.9 0.0 1.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 CEH18303.1 - 0.00014 20.9 0.0 0.00041 19.3 0.0 1.7 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 CEH18303.1 - 0.00046 19.7 1.9 0.0025 17.4 0.4 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MOSC_N PF03476.11 CEH18304.1 - 2.8e-23 81.8 0.0 5.8e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 CEH18304.1 - 6e-08 32.2 0.3 7.7e-06 25.4 0.1 3.1 2 1 0 2 2 2 1 MOSC domain LRR_6 PF13516.1 CEH18305.1 - 8.6e-14 50.0 12.3 0.064 13.3 0.1 7.9 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.2 CEH18305.1 - 1.6e-06 27.5 0.4 1.7 8.3 0.0 5.5 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) adh_short PF00106.20 CEH18306.1 - 1.1e-14 54.6 0.1 1.9e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH18306.1 - 3e-06 27.0 0.0 5.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CEH18306.1 - 0.00053 20.0 0.1 0.0014 18.6 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 CEH18306.1 - 0.00062 19.6 0.0 0.00097 18.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.10 CEH18306.1 - 0.025 14.1 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 YjeF-related protein N-terminus Saccharop_dh PF03435.13 CEH18306.1 - 0.031 13.2 0.1 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 CEH18306.1 - 0.047 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 CEH18306.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GCS PF03074.11 CEH18307.1 - 2.4e-170 566.5 0.0 8e-135 449.6 0.0 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase GCS2 PF04107.8 CEH18307.1 - 0.071 12.2 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) W2 PF02020.13 CEH18308.1 - 3.1e-12 46.2 0.0 8.3e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon ArfGap PF01412.13 CEH18309.1 - 5.9e-20 71.1 0.1 9.6e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Abhydrolase_5 PF12695.2 CEH18310.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family HhH-GPD PF00730.20 CEH18311.1 - 3.4e-09 36.9 0.0 5.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Herpes_UL32 PF06070.6 CEH18311.1 - 0.44 8.9 7.6 0.62 8.4 5.2 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Lipase_GDSL_2 PF13472.1 CEH18312.1 - 2.3e-16 60.4 0.0 3.6e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CEH18312.1 - 2e-15 57.2 0.0 2.8e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALAD PF00490.16 CEH18314.1 - 2.9e-116 387.8 0.0 3.2e-116 387.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Lactamase_B PF00753.22 CEH18315.1 - 5.1e-24 85.0 1.0 7e-24 84.5 0.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CEH18315.1 - 0.0018 17.8 0.1 0.0029 17.1 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LRR_4 PF12799.2 CEH18316.1 - 0.00041 19.9 7.2 0.0085 15.6 1.5 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CEH18316.1 - 0.026 14.5 9.5 2.9 8.2 0.1 4.7 3 1 1 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.1 CEH18316.1 - 0.06 13.1 12.4 0.31 10.8 4.9 3.3 2 1 1 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 CEH18316.1 - 0.58 10.4 9.5 11 6.5 0.2 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 CEH18316.1 - 1.2 9.6 5.7 15 6.3 0.1 4.1 3 0 0 3 3 3 0 Leucine rich repeat Tho2 PF11262.3 CEH18317.1 - 1.8e-69 234.0 0.0 3e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 CEH18317.1 - 3.8e-29 100.2 0.3 9.3e-29 99.0 0.0 1.8 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Vac14_Fig4_bd PF11916.3 CEH18317.1 - 0.17 11.0 0.1 0.37 9.9 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding GFO_IDH_MocA PF01408.17 CEH18318.1 - 3.4e-20 72.7 0.2 5.2e-20 72.1 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 CEH18318.1 - 0.066 13.6 0.1 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain SNARE PF05739.14 CEH18319.1 - 1.1e-18 66.6 1.4 2.7e-18 65.3 0.5 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CEH18319.1 - 1.8e-15 56.9 2.6 3.2e-15 56.1 0.1 2.2 2 1 0 2 2 2 1 Syntaxin Syntaxin-18_N PF10496.4 CEH18319.1 - 7.3e-05 22.5 0.7 0.00098 18.9 0.1 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DUF1664 PF07889.7 CEH18319.1 - 0.067 12.9 0.4 3.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 CEH18319.1 - 0.42 9.0 2.0 0.36 9.2 0.2 1.6 2 0 0 2 2 2 0 AAA domain Glyco_tranf_2_3 PF13641.1 CEH18320.1 - 2.8e-26 92.7 0.5 1.7e-15 57.4 0.1 2.1 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CEH18320.1 - 2.3e-09 37.1 0.0 4.1e-07 29.8 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CEH18320.1 - 6.5e-09 35.3 0.1 0.00015 21.0 0.0 2.8 1 1 1 2 2 2 2 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 CEH18320.1 - 0.013 13.8 0.0 0.083 11.2 0.0 1.9 1 1 0 1 1 1 0 Chitin synthase HSBP1 PF06825.7 CEH18321.1 - 3.2e-12 45.8 0.1 4.3e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 TRCF PF03461.10 CEH18321.1 - 0.0075 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 TRCF domain TroA PF01297.12 CEH18321.1 - 0.018 14.3 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Periplasmic solute binding protein family HR1 PF02185.11 CEH18321.1 - 0.035 13.8 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Hr1 repeat FlaC_arch PF05377.6 CEH18321.1 - 0.15 11.9 0.3 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) LZ_Tnp_IS66 PF13007.2 CEH18321.1 - 0.82 10.3 0.0 0.82 10.3 0.0 2.4 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain K_oxygenase PF13434.1 CEH18322.1 - 1.4e-62 211.5 0.0 1.8e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 CEH18322.1 - 7.3e-06 26.1 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HCR PF07111.7 CEH18322.1 - 0.0017 16.4 0.1 0.0024 15.9 0.0 1.1 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) NAD_binding_9 PF13454.1 CEH18322.1 - 0.0056 16.4 0.0 0.43 10.3 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 CEH18322.1 - 0.13 12.6 0.1 0.6 10.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ras PF00071.17 CEH18324.1 - 1.5e-65 219.5 4.6 1.2e-50 171.0 1.0 2.1 1 1 1 2 2 2 2 Ras family Miro PF08477.8 CEH18324.1 - 4.3e-20 72.3 0.3 9.5e-18 64.8 0.1 2.5 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 CEH18324.1 - 6.8e-14 51.4 2.0 3.3e-10 39.4 0.4 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEH18324.1 - 5.4e-10 39.0 0.1 7.6e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CEH18324.1 - 0.0002 21.3 0.1 0.0006 19.7 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CEH18324.1 - 0.00066 18.8 0.6 0.0033 16.5 0.4 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CEH18324.1 - 0.0016 17.7 0.3 0.28 10.3 0.0 2.3 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CEH18324.1 - 0.0021 18.2 0.0 0.24 11.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 CEH18324.1 - 0.0084 15.4 0.2 0.35 10.1 0.1 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B MobB PF03205.9 CEH18324.1 - 0.015 14.9 0.2 3.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CEH18324.1 - 0.015 15.2 0.1 5 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CEH18324.1 - 0.06 13.1 0.2 3.9 7.2 0.0 2.6 2 1 1 3 3 3 0 Dynamin family BA14K PF07886.6 CEH18324.1 - 0.19 11.4 4.1 8.9 6.0 0.2 2.5 2 0 0 2 2 2 0 BA14K-like protein BOP1NT PF08145.7 CEH18325.1 - 1.7e-100 336.0 5.6 2.5e-100 335.5 3.9 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CEH18325.1 - 1.2e-28 97.9 2.6 5.1e-07 29.3 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat TEX19 PF15553.1 CEH18325.1 - 1.7 8.4 9.4 39 4.0 5.4 2.6 2 0 0 2 2 2 0 Testis-expressed protein 19 Actin PF00022.14 CEH18326.1 - 1.1e-30 106.4 0.0 7e-26 90.5 0.0 3.4 3 1 0 3 3 3 3 Actin Aldedh PF00171.17 CEH18328.1 - 2.3e-72 243.8 0.0 2.8e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Seryl_tRNA_N PF02403.17 CEH18329.1 - 0.011 15.7 1.6 0.025 14.5 0.1 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.1 CEH18329.1 - 0.072 12.0 9.5 0.12 11.2 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 CEH18329.1 - 0.12 10.8 0.2 0.14 10.5 0.1 1.0 1 0 0 1 1 1 0 AAA domain ApoLp-III PF07464.6 CEH18329.1 - 0.5 10.3 8.6 1.9 8.4 5.8 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.7 CEH18329.1 - 1.7 8.4 6.9 4.1 7.2 3.4 2.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Aminotran_1_2 PF00155.16 CEH18330.1 - 1e-42 146.3 0.1 1.6e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CEH18330.1 - 3e-07 29.5 0.0 4.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CEH18330.1 - 5.7e-05 21.5 0.0 9e-05 20.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CEH18330.1 - 0.00028 20.1 0.2 0.00061 19.0 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CEH18330.1 - 0.023 13.7 0.1 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Osmo_CC PF08946.5 CEH18330.1 - 0.1 12.6 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 Osmosensory transporter coiled coil TEA PF01285.13 CEH18333.1 - 9e-35 120.6 2.4 9e-35 120.6 0.0 2.2 2 0 0 2 2 2 1 TEA/ATTS domain family Pyridoxal_deC PF00282.14 CEH18334.1 - 7.9e-22 77.2 0.2 1.3e-14 53.4 0.1 2.8 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 CEH18334.1 - 0.00019 20.7 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CEH18334.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 CEH18334.1 - 0.018 13.5 0.0 0.47 8.8 0.0 2.4 2 1 1 3 3 3 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Peptidase_S10 PF00450.17 CEH18335.1 - 8.9e-91 305.1 0.2 1.1e-90 304.8 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CEH18335.1 - 0.0026 17.6 0.0 0.0091 15.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4215 PF13948.1 CEH18335.1 - 0.12 12.5 0.2 0.36 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) Ndc1_Nup PF09531.5 CEH18337.1 - 9e-28 97.0 5.3 9e-28 97.0 3.7 1.6 2 0 0 2 2 2 1 Nucleoporin protein Ndc1-Nup COesterase PF00135.23 CEH18338.1 - 1.4e-82 278.1 2.5 1.1e-73 248.7 0.3 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CEH18338.1 - 6e-06 25.9 0.2 0.0011 18.5 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Y_phosphatase2 PF03162.8 CEH18339.1 - 1.9e-55 186.7 0.1 2.7e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CEH18339.1 - 6.5e-07 29.7 0.0 1.8e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CEH18339.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CEH18339.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain MmgE_PrpD PF03972.9 CEH18340.1 - 7.8e-142 472.5 0.0 9.9e-142 472.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RabGAP-TBC PF00566.13 CEH18341.1 - 1.5e-21 76.9 0.9 5.7e-17 61.8 0.2 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GMP_synt_C PF00958.17 CEH18342.1 - 2.1e-39 133.1 0.0 4.4e-39 132.0 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 CEH18342.1 - 1.3e-37 129.0 0.0 3.4e-37 127.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 CEH18342.1 - 5.1e-11 41.9 0.1 3.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 CEH18342.1 - 2e-10 40.4 0.0 3.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 CEH18342.1 - 0.00055 18.5 0.3 0.001 17.6 0.1 1.5 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 CEH18342.1 - 0.00058 19.3 0.0 0.0012 18.3 0.0 1.5 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 CEH18342.1 - 0.0011 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 CEH18342.1 - 0.0036 16.6 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 CEH18342.1 - 0.013 14.5 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Arginosuccinate synthase HOASN PF14515.1 CEH18342.1 - 0.15 12.4 0.5 0.37 11.1 0.1 1.7 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices PCNA_N PF00705.13 CEH18343.1 - 3.2e-50 168.9 2.3 6e-50 168.0 1.6 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CEH18343.1 - 1.2e-40 138.4 0.3 8.8e-20 70.9 0.0 3.2 3 1 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 CEH18343.1 - 0.005 15.9 0.0 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 Rad9 ICMT PF04140.9 CEH18344.1 - 7.8e-15 54.8 0.3 8.9e-14 51.4 0.2 2.2 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CEH18344.1 - 3e-10 40.1 1.0 3e-10 40.1 0.7 1.7 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 CEH18344.1 - 0.06 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF202 PF02656.10 CEH18344.1 - 0.36 11.0 2.7 7.5 6.8 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF1469 PF07332.6 CEH18344.1 - 2.8 7.6 9.0 0.15 11.8 1.6 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) Zn_clus PF00172.13 CEH18346.1 - 0.00054 19.8 9.1 0.00054 19.8 6.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CASP_C PF08172.7 CEH18347.1 - 6.2e-54 182.6 6.1 6.2e-54 182.6 4.3 4.0 2 1 0 3 3 3 1 CASP C terminal DUF3649 PF12365.3 CEH18347.1 - 0.18 11.3 0.4 0.44 10.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) ThiF PF00899.16 CEH18348.1 - 1.8e-31 108.7 0.0 4.2e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CEH18348.1 - 0.0021 18.1 0.0 0.0055 16.7 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CEH18348.1 - 0.17 11.0 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2296 PF10058.4 CEH18349.1 - 3e-18 65.2 0.6 4.9e-18 64.6 0.4 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) zf-tcix PF14952.1 CEH18349.1 - 0.062 12.6 0.7 0.14 11.5 0.5 1.5 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding COG5 PF10392.4 CEH18349.1 - 0.18 11.7 0.2 0.32 10.9 0.2 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 zf-RanBP PF00641.13 CEH18349.1 - 0.8 8.8 3.6 1.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others ATP11 PF06644.6 CEH18350.1 - 1.3e-67 228.1 0.5 1.9e-67 227.5 0.4 1.2 1 0 0 1 1 1 1 ATP11 protein Rab5ip PF07019.7 CEH18351.1 - 5.4e-05 23.2 9.1 0.00017 21.6 6.2 1.8 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DAGK_cat PF00781.19 CEH18352.1 - 2.6e-20 72.1 0.2 5.8e-20 71.0 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SNARE_assoc PF09335.6 CEH18353.1 - 2.2e-13 50.4 6.7 5.5e-13 49.2 4.7 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein Lin-8 PF03353.10 CEH18353.1 - 1.5 8.0 3.1 2.8 7.1 2.2 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mob1_phocein PF03637.12 CEH18355.1 - 5.2e-75 250.9 0.0 6.1e-75 250.7 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Acetyltransf_1 PF00583.19 CEH18356.1 - 3.1e-06 27.1 0.1 1.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEH18356.1 - 0.0018 18.4 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CEH18356.1 - 0.041 13.7 0.4 0.092 12.6 0.3 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase 2OG-FeII_Oxy_5 PF13759.1 CEH18356.1 - 0.088 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Acetyltransf_10 PF13673.1 CEH18356.1 - 0.17 12.0 0.2 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MSP1_C PF07462.6 CEH18357.1 - 4.8 5.4 4.7 6.2 5.0 3.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus VPS9 PF02204.13 CEH18358.1 - 1.6e-13 50.5 0.0 3.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Peptidase_S10 PF00450.17 CEH18359.1 - 8.4e-102 341.4 0.2 1.2e-101 340.8 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CEH18359.1 - 1.7e-05 24.8 0.0 0.018 14.8 0.0 2.6 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF883 PF05957.8 CEH18359.1 - 0.14 12.5 0.3 0.49 10.8 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Phosducin PF02114.11 CEH18360.1 - 9.6e-15 54.0 0.1 2.6e-09 36.1 0.0 3.3 3 0 0 3 3 3 3 Phosducin Rbsn PF11464.3 CEH18360.1 - 0.098 12.2 0.4 0.23 11.0 0.3 1.6 1 0 0 1 1 1 0 Rabenosyn Rab binding domain zf-C3HC4_2 PF13923.1 CEH18361.1 - 2.3e-09 37.1 2.5 2.3e-09 37.1 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH18361.1 - 5.9e-09 35.4 1.6 5.9e-09 35.4 1.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEH18361.1 - 1.3e-06 28.1 7.4 1.3e-05 24.9 5.4 2.1 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 CEH18361.1 - 4.5e-06 26.4 3.5 4.5e-06 26.4 2.4 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CEH18361.1 - 2.1e-05 24.0 3.2 7.9e-05 22.2 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH18361.1 - 3.8e-05 23.3 1.5 3.8e-05 23.3 1.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CEH18361.1 - 0.00025 20.6 1.8 0.00025 20.6 1.2 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 CEH18361.1 - 0.076 12.5 0.1 0.18 11.3 0.1 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Fe-S_biosyn PF01521.15 CEH18363.1 - 1.2e-08 34.8 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SAS4 PF15460.1 CEH18364.1 - 0.00045 20.0 3.8 0.00095 19.0 2.7 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 CEH18364.1 - 0.0049 17.3 1.5 0.0049 17.3 1.0 3.8 4 0 0 4 4 4 1 PEHE domain TPR_11 PF13414.1 CEH18365.1 - 3.6e-28 97.0 59.4 2.8e-11 42.9 0.5 14.1 10 5 6 16 16 16 11 TPR repeat TPR_16 PF13432.1 CEH18365.1 - 1.2e-23 83.2 110.8 1e-07 32.4 1.9 17.7 10 7 10 20 20 20 12 Tetratricopeptide repeat TPR_2 PF07719.12 CEH18365.1 - 5.3e-20 69.6 55.3 3.4e-05 23.4 0.4 16.8 17 1 0 17 17 16 4 Tetratricopeptide repeat TPR_14 PF13428.1 CEH18365.1 - 8.1e-18 63.3 89.0 9e-06 25.8 0.3 20.1 15 5 6 21 21 20 6 Tetratricopeptide repeat TPR_17 PF13431.1 CEH18365.1 - 1.3e-17 62.4 21.6 0.0024 17.9 0.1 14.9 15 1 1 16 16 15 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEH18365.1 - 2.5e-16 58.1 17.9 0.0016 18.0 0.1 11.1 12 1 0 12 12 12 5 Tetratricopeptide repeat TPR_1 PF00515.23 CEH18365.1 - 1.4e-15 56.1 35.7 2.5e-05 23.6 0.1 13.8 15 1 0 15 15 15 4 Tetratricopeptide repeat TPR_19 PF14559.1 CEH18365.1 - 5.1e-13 49.1 65.3 0.00014 22.1 0.0 13.2 10 3 3 14 14 14 7 Tetratricopeptide repeat TPR_12 PF13424.1 CEH18365.1 - 1.5e-11 44.0 60.0 0.00032 20.5 0.8 12.2 10 2 2 12 12 12 7 Tetratricopeptide repeat ChAPs PF09295.5 CEH18365.1 - 0.00018 20.3 0.7 0.78 8.4 0.0 3.4 3 1 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.1 CEH18365.1 - 0.00024 20.9 0.9 0.00024 20.9 0.7 9.7 11 1 1 12 12 11 1 Tetratricopeptide repeat TPR_7 PF13176.1 CEH18365.1 - 0.00054 19.5 28.4 1.7 8.6 0.0 10.2 10 0 0 10 10 10 3 Tetratricopeptide repeat NARP1 PF12569.3 CEH18365.1 - 0.0014 17.4 10.6 0.015 14.0 1.5 3.8 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 tRNA-synt_2c PF01411.14 CEH18366.1 - 5.3e-210 698.3 0.0 6.7e-210 698.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CEH18366.1 - 6.2e-14 51.6 0.4 1.3e-13 50.6 0.3 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CEH18366.1 - 0.0019 17.8 0.9 0.0019 17.8 0.6 2.1 2 0 0 2 2 2 1 DHHA1 domain SpoVS PF04232.7 CEH18367.1 - 0.082 12.4 0.4 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Stage V sporulation protein S (SpoVS) TspO_MBR PF03073.10 CEH18367.1 - 0.27 10.7 5.7 0.49 9.8 3.9 1.4 1 0 0 1 1 1 0 TspO/MBR family HMD PF03201.11 CEH18367.1 - 0.28 11.1 1.9 1.2 9.1 0.0 2.6 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF2721 PF11026.3 CEH18367.1 - 2.2 7.9 7.3 0.29 10.7 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) TPR_11 PF13414.1 CEH18369.1 - 2.6e-25 87.8 10.0 8.2e-14 51.0 0.1 4.2 2 2 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 CEH18369.1 - 8.4e-21 72.6 0.1 2.8e-05 23.5 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEH18369.1 - 6.2e-14 50.7 7.9 0.00021 20.9 0.0 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 CEH18369.1 - 1.3e-12 46.8 6.6 0.0023 18.0 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CEH18369.1 - 1.3e-11 44.8 9.2 4.3e-06 27.2 0.1 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CEH18369.1 - 1.5e-11 44.0 9.0 3.8e-07 29.9 0.1 4.2 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEH18369.1 - 7.4e-10 38.5 14.6 0.00062 20.1 0.0 6.2 4 2 3 7 7 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 CEH18369.1 - 8.9e-10 37.6 1.5 0.018 14.7 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEH18369.1 - 5.4e-06 26.1 3.6 0.03 14.1 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEH18369.1 - 9.6e-06 25.0 0.0 0.5 10.2 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CEH18369.1 - 1.1e-05 25.6 9.5 0.04 14.2 0.0 4.9 3 2 2 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 CEH18369.1 - 0.011 15.8 0.4 0.011 15.8 0.3 2.9 4 0 0 4 4 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 CEH18369.1 - 0.048 13.4 0.1 18 5.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 CEH18369.1 - 0.052 13.6 12.8 0.24 11.5 1.1 5.2 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 CEH18369.1 - 0.099 12.6 9.3 0.23 11.4 0.4 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat adh_short_C2 PF13561.1 CEH18370.1 - 6.8e-31 107.8 0.4 8.8e-31 107.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEH18370.1 - 2e-28 99.4 2.0 2.8e-28 98.9 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH18370.1 - 1.6e-19 70.3 0.5 2.2e-19 69.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CEH18370.1 - 0.0038 16.6 0.4 0.0058 16.0 0.3 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CoA_binding PF02629.14 CEH18370.1 - 0.057 13.9 1.4 0.18 12.3 0.1 2.2 2 1 0 2 2 2 0 CoA binding domain NAD_binding_10 PF13460.1 CEH18370.1 - 0.1 12.5 1.9 0.66 9.9 1.1 2.0 1 1 1 2 2 2 0 NADH(P)-binding DUF2493 PF10686.4 CEH18370.1 - 3.2 7.3 7.3 21 4.7 1.4 3.9 2 2 3 5 5 5 0 Protein of unknown function (DUF2493) Glyco_hydro_17 PF00332.13 CEH18371.1 - 3e-05 23.2 0.7 0.073 12.1 0.0 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 VirB8 PF04335.8 CEH18371.1 - 0.043 13.3 0.2 0.089 12.3 0.1 1.4 1 0 0 1 1 1 0 VirB8 protein OppC_N PF12911.2 CEH18371.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C FDC-SP PF15215.1 CEH18374.1 - 0.16 12.2 1.0 0.21 11.9 0.6 1.5 1 1 0 1 1 1 0 Follicular dendritic cell secreted peptide PAP_central PF04928.12 CEH18376.1 - 1.7e-106 354.6 0.0 2.3e-106 354.2 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CEH18376.1 - 4.5e-41 139.9 0.0 7e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CEH18376.1 - 3.2e-08 33.7 0.0 2.1e-07 31.1 0.0 2.2 1 1 1 2 2 2 1 Nucleotidyltransferase domain Nrap PF03813.9 CEH18376.1 - 0.0091 13.5 0.0 0.012 13.1 0.0 1.1 1 0 0 1 1 1 1 Nrap protein DUF1014 PF06244.7 CEH18377.1 - 6.4e-24 84.5 9.5 2.3e-23 82.7 6.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) TspO_MBR PF03073.10 CEH18378.1 - 6.1e-37 126.3 11.3 7.1e-37 126.1 7.8 1.0 1 0 0 1 1 1 1 TspO/MBR family bZIP_1 PF00170.16 CEH18379.1 - 7.7e-09 35.3 4.8 1.4e-08 34.5 3.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEH18379.1 - 4.2e-06 26.4 4.7 7.5e-06 25.6 3.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper MRJP PF03022.11 CEH18380.1 - 1.3e-30 106.5 0.0 2.3e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Major royal jelly protein Phytase-like PF13449.1 CEH18380.1 - 0.0011 18.3 0.0 0.011 15.0 0.0 2.1 1 1 0 1 1 1 1 Esterase-like activity of phytase PQQ_2 PF13360.1 CEH18380.1 - 0.0017 17.8 0.4 0.0092 15.4 0.0 2.3 3 1 0 3 3 3 1 PQQ-like domain PD40 PF07676.7 CEH18380.1 - 0.013 15.1 0.0 0.047 13.3 0.0 2.0 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Reg_prop PF07494.6 CEH18380.1 - 0.11 12.5 0.0 0.6 10.3 0.0 2.3 1 0 0 1 1 1 0 Two component regulator propeller GWT1 PF06423.7 CEH18382.1 - 0.016 15.2 0.7 0.028 14.4 0.5 1.4 1 0 0 1 1 1 0 GWT1 DUF1682 PF07946.9 CEH18383.1 - 5.6e-59 199.5 0.0 6.5e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RNase_H2-Ydr279 PF09468.5 CEH18383.1 - 0.0042 16.3 2.8 0.0057 15.8 2.0 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Peptidase_S49_N PF08496.5 CEH18383.1 - 3.6 7.3 9.1 11 5.7 6.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Nucleoporin_C PF03177.9 CEH18384.1 - 6.6e-63 213.1 11.1 9.6e-63 212.6 7.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CEH18384.1 - 1.6e-13 50.2 0.0 2.9e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like DUF2405 PF10293.4 CEH18386.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) Y_phosphatase3C PF13348.1 CEH18388.1 - 0.053 13.6 0.0 0.079 13.0 0.0 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family C-terminal region ETRAMP PF09716.5 CEH18389.1 - 3.2e-05 23.7 5.2 0.031 14.2 0.0 3.4 1 1 2 3 3 3 1 Malarial early transcribed membrane protein (ETRAMP) RGM_C PF06534.8 CEH18389.1 - 0.6 9.2 6.6 0.82 8.8 4.6 1.1 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus DUF966 PF06136.8 CEH18389.1 - 1.2 8.5 19.0 1.4 8.2 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ARGLU PF15346.1 CEH18389.1 - 5 6.8 59.4 2.3 7.9 20.8 2.1 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 Asp-B-Hydro_N PF05279.6 CEH18389.1 - 8 6.2 38.7 11 5.7 26.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Metallophos PF00149.23 CEH18390.1 - 9.9e-43 145.8 1.3 1.3e-42 145.5 0.9 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NDUF_B8 PF05821.6 CEH18391.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) RCC1 PF00415.13 CEH18392.1 - 6.8e-21 74.2 3.9 2.6e-05 24.3 0.0 5.9 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CEH18392.1 - 1.2e-10 40.7 5.5 2.2e-06 27.0 0.0 4.8 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CEH18392.1 - 5.4e-06 26.3 0.0 6.8e-05 22.8 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain Ank_4 PF13637.1 CEH18392.1 - 1.6e-05 25.2 0.5 0.00033 21.0 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CEH18392.1 - 0.00037 20.1 0.1 0.0011 18.6 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 CEH18392.1 - 0.0018 18.3 0.6 0.021 15.0 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 CEH18392.1 - 0.0061 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CEH18392.1 - 0.11 12.7 0.2 0.36 11.1 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF4646 PF15496.1 CEH18394.1 - 2.1e-20 73.0 0.0 5.2e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) PAT1 PF09770.4 CEH18394.1 - 6.7 4.8 17.5 10 4.2 12.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med19 PF10278.4 CEH18394.1 - 8.4 6.0 10.2 1.8 8.2 4.8 1.5 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 V-ATPase_G PF03179.10 CEH18395.1 - 0.065 13.5 6.8 0.11 12.8 4.7 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Striatin PF08232.7 CEH18395.1 - 0.86 9.9 5.5 1.4 9.2 3.8 1.3 1 0 0 1 1 1 0 Striatin family Menin PF05053.8 CEH18395.1 - 1.4 7.0 6.4 1.6 6.8 4.5 1.0 1 0 0 1 1 1 0 Menin eIF-3c_N PF05470.7 CEH18395.1 - 2.4 6.1 6.8 3.1 5.7 4.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4407 PF14362.1 CEH18395.1 - 8 5.3 6.4 11 4.8 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GCD14 PF08704.5 CEH18396.1 - 1.1e-45 156.1 0.2 5.6e-26 91.5 0.1 2.1 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 CEH18396.1 - 0.00028 20.8 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CEH18396.1 - 0.037 13.5 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SF3b10 PF07189.6 CEH18397.1 - 1.4e-29 101.7 0.0 1.6e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) RhoGEF PF00621.15 CEH18399.1 - 3.3e-12 46.6 0.0 9.8e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain DUF1765 PF08578.5 CEH18400.1 - 3e-28 98.4 4.3 4.5e-28 97.8 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) DUF4407 PF14362.1 CEH18401.1 - 3.1 6.6 19.7 4.7 6.0 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Arrestin_C PF02752.17 CEH18402.1 - 1.1e-17 64.4 0.0 4.1e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEH18402.1 - 0.00017 21.4 0.0 0.0057 16.4 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Seipin PF06775.9 CEH18404.1 - 7.2e-43 146.4 0.0 9.9e-43 145.9 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) PTE PF02126.13 CEH18404.1 - 0.25 10.3 0.0 0.48 9.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotriesterase family DUF3425 PF11905.3 CEH18405.1 - 2.9e-22 79.0 1.3 7.4e-22 77.7 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Pkinase PF00069.20 CEH18406.1 - 7e-54 182.6 0.0 8.5e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH18406.1 - 1.7e-36 125.6 0.0 2.1e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH18406.1 - 2.9e-07 29.7 0.0 5.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CEH18406.1 - 0.0051 16.5 0.0 0.04 13.6 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family zf-CCCH PF00642.19 CEH18407.1 - 2.1e-12 46.3 16.0 2.2e-06 27.1 2.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CEH18407.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 CEH18407.1 - 0.44 10.5 2.6 7.4 6.5 0.4 2.5 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) RasGAP PF00616.14 CEH18408.1 - 1.6e-26 93.2 0.0 2.7e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF2207 PF09972.4 CEH18409.1 - 0.002 16.7 0.1 0.0028 16.3 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Rifin_STEVOR PF02009.11 CEH18409.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family DUF2029 PF09594.5 CEH18409.1 - 0.034 13.6 4.1 0.046 13.2 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) SKG6 PF08693.5 CEH18409.1 - 0.88 8.9 5.5 2 7.8 3.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UQ_con PF00179.21 CEH18413.1 - 2e-22 79.1 0.0 2.9e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Transferase PF02458.10 CEH18414.1 - 7.7e-34 116.8 0.0 7.4e-32 110.3 0.0 2.0 1 1 0 1 1 1 1 Transferase family Condensation PF00668.15 CEH18414.1 - 5.7e-08 31.9 0.0 9.6e-08 31.2 0.0 1.3 1 0 0 1 1 1 1 Condensation domain MULE PF10551.4 CEH18417.1 - 1.9e-07 31.1 0.0 5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Fungal_trans PF04082.13 CEH18420.1 - 2.6e-26 92.0 0.2 4.1e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 CEH18420.1 - 2.2e-07 30.8 13.2 0.00087 19.4 0.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH18420.1 - 0.0001 22.3 11.5 0.041 14.2 0.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Exo_endo_phos PF03372.18 CEH18421.1 - 1.6e-14 54.4 0.2 2.2e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Amidase PF01425.16 CEH18423.1 - 1.3e-74 251.7 0.0 2.7e-60 204.4 0.1 2.1 2 0 0 2 2 2 2 Amidase Sec7 PF01369.15 CEH18424.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 Sec7 domain DRMBL PF07522.9 CEH18426.1 - 2.2e-29 101.6 0.0 4.2e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CEH18426.1 - 0.002 17.7 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sigma70_ner PF04546.8 CEH18427.1 - 0.017 14.7 4.2 0.022 14.3 2.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 CEH18427.1 - 0.062 12.4 4.0 0.062 12.4 2.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Herpes_DNAp_acc PF04929.7 CEH18427.1 - 0.31 9.9 4.1 0.34 9.8 2.8 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Tom37_C PF11801.3 CEH18427.1 - 0.44 10.3 4.8 0.56 10.0 3.4 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Sporozoite_P67 PF05642.6 CEH18427.1 - 0.52 8.1 6.1 0.52 8.1 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RR_TM4-6 PF06459.7 CEH18427.1 - 2 8.2 8.0 2.1 8.1 5.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3381 PF11861.3 CEH18427.1 - 2.9 7.3 12.2 4.4 6.7 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.9 CEH18427.1 - 4.9 5.0 11.4 4.8 5.0 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DEAD PF00270.24 CEH18428.1 - 1.5e-36 125.4 0.0 2.7e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH18428.1 - 2.9e-23 81.5 0.0 4.4e-22 77.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CEH18428.1 - 0.089 12.9 0.4 1.6 8.8 0.2 2.9 2 1 0 2 2 2 0 AAA domain SSI PF00720.12 CEH18428.1 - 1.1 9.1 3.9 11 5.9 0.4 2.5 1 1 1 2 2 2 0 Subtilisin inhibitor-like NUDIX PF00293.23 CEH18429.1 - 2.1e-15 56.5 0.1 8.5e-15 54.5 0.0 1.9 3 0 0 3 3 3 1 NUDIX domain NUDIX-like PF09296.6 CEH18429.1 - 5.5e-13 49.1 0.1 1.9e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain JAB PF01398.16 CEH18430.1 - 7.6e-46 154.5 0.5 4.7e-30 103.6 0.0 2.5 1 1 1 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CEH18430.1 - 3.7e-26 91.4 0.5 8.9e-26 90.2 0.4 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CEH18430.1 - 2.5e-11 43.0 0.0 1.1e-06 28.1 0.0 2.3 1 1 1 2 2 2 2 Prokaryotic homologs of the JAB domain GDI PF00996.13 CEH18433.1 - 7.8e-52 176.0 0.0 5.8e-51 173.1 0.0 1.9 2 0 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CEH18433.1 - 0.0023 17.9 0.1 0.0048 16.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pkinase PF00069.20 CEH18435.1 - 1.3e-71 240.7 0.0 1.7e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH18435.1 - 4.2e-36 124.3 0.0 5.5e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH18435.1 - 6.9e-07 28.5 0.0 9.8e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CEH18435.1 - 7.7e-05 22.1 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CEH18435.1 - 8.4e-05 21.7 0.0 0.00017 20.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEH18435.1 - 0.00025 20.8 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CEH18435.1 - 0.06 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase PRKCSH PF07915.8 CEH18436.1 - 5.7e-16 59.0 0.0 2.9e-15 56.8 0.0 2.2 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein CIMR PF00878.13 CEH18436.1 - 0.038 13.7 0.2 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 CEH18436.1 - 0.046 13.2 0.1 0.087 12.2 0.1 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein DUF2237 PF09996.4 CEH18437.1 - 1.3e-34 118.1 0.0 3.5e-34 116.7 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Nic96 PF04097.9 CEH18438.1 - 3.1e-129 431.9 0.0 3.1e-66 223.7 0.2 2.4 1 1 1 2 2 2 2 Nup93/Nic96 GHMP_kinases_N PF00288.21 CEH18439.1 - 7.2e-11 42.0 0.4 1.9e-10 40.6 0.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CEH18439.1 - 0.00014 22.0 0.2 0.00042 20.4 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal TPR_11 PF13414.1 CEH18440.1 - 7.2e-18 64.0 19.6 4.8e-07 29.3 0.3 5.9 4 1 2 6 6 6 4 TPR repeat TPR_16 PF13432.1 CEH18440.1 - 1.7e-10 41.2 25.4 0.02 15.5 4.5 7.2 4 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 CEH18440.1 - 6.6e-10 39.1 7.0 0.11 12.8 0.2 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CEH18440.1 - 1.2e-09 37.3 13.1 0.12 12.0 0.1 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 CEH18440.1 - 2.6e-09 36.3 25.3 0.069 13.1 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 CEH18440.1 - 1.2e-08 34.8 34.7 0.024 15.2 0.1 8.6 5 1 4 9 9 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 CEH18440.1 - 6.4e-07 29.0 10.7 0.039 14.1 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 CEH18440.1 - 8e-06 25.9 9.8 0.0035 17.4 0.1 3.7 3 1 1 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CEH18440.1 - 3.6e-05 23.6 19.1 0.058 13.3 0.1 5.7 3 1 3 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 CEH18440.1 - 0.00086 18.9 10.1 14 5.7 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEH18440.1 - 0.0032 17.1 3.8 1e+02 3.0 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 CEH18440.1 - 0.15 12.5 8.2 5.3 7.7 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat PAP2 PF01569.16 CEH18441.1 - 3.5e-11 42.8 4.6 8.3e-11 41.6 3.2 1.5 1 0 0 1 1 1 1 PAP2 superfamily MgtC PF02308.11 CEH18441.1 - 0.048 13.5 0.2 0.096 12.5 0.2 1.4 1 0 0 1 1 1 0 MgtC family GTP_CH_N PF12471.3 CEH18442.1 - 3.7e-80 268.1 0.0 5.1e-80 267.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 CEH18442.1 - 8.4e-16 57.6 0.0 2e-15 56.4 0.0 1.6 2 0 0 2 2 2 1 GTP cyclohydrolase II EF-hand_1 PF00036.27 CEH18443.1 - 2.7e-21 73.2 0.3 1.9e-05 23.6 0.0 4.9 5 1 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 CEH18443.1 - 3.6e-20 69.9 0.2 1.3e-05 24.6 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 CEH18443.1 - 4.2e-18 65.2 0.0 1.5e-07 31.4 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CEH18443.1 - 3.1e-17 61.0 0.2 9.9e-05 21.5 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CEH18443.1 - 6.4e-14 51.3 0.3 2.8e-08 33.2 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CEH18443.1 - 0.046 13.6 0.0 18 5.3 0.0 3.6 3 1 0 3 3 3 0 EF-hand domain Vps39_2 PF10367.4 CEH18444.1 - 3.3e-24 85.1 0.0 7.2e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 CEH18444.1 - 0.0005 20.0 0.4 0.017 15.0 0.0 3.0 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 CEH18444.1 - 0.0037 16.8 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Region in Clathrin and VPS TPR_5 PF12688.2 CEH18444.1 - 0.015 15.3 1.1 0.04 13.9 0.2 2.1 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_1 PF00515.23 CEH18444.1 - 0.04 13.5 0.4 3.2 7.4 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CEH18444.1 - 0.086 12.6 0.4 8.8 6.3 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.19 CEH18447.1 - 2.1e-12 46.9 0.0 2.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEH18447.1 - 7e-11 42.1 0.0 8.3e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEH18447.1 - 0.00066 19.5 0.0 0.00077 19.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEH18447.1 - 0.0031 17.2 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CEH18447.1 - 0.01 15.9 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CEH18447.1 - 0.015 15.4 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pro_isomerase PF00160.16 CEH18448.1 - 1e-36 126.4 0.0 1.9e-36 125.5 0.0 1.4 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cytotoxic PF09000.5 CEH18448.1 - 0.043 13.8 1.5 0.07 13.1 0.2 1.9 1 1 1 2 2 2 0 Cytotoxic WD40 PF00400.27 CEH18449.1 - 3.9e-05 23.3 2.6 0.0001 22.0 0.2 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat His_Phos_2 PF00328.17 CEH18450.1 - 4.7e-22 78.7 0.0 5.6e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1590 PF07629.6 CEH18450.1 - 0.13 11.8 0.9 0.36 10.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) COG2 PF06148.6 CEH18451.1 - 4e-21 75.2 0.1 1.7e-20 73.2 0.0 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 CEH18451.1 - 2.8e-10 40.3 0.0 7.7e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) His_Phos_1 PF00300.17 CEH18453.1 - 3.2e-16 59.8 3.9 4.7e-16 59.2 2.7 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2251 PF10008.4 CEH18455.1 - 0.078 13.1 0.2 11 6.1 0.0 3.2 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2251) ADH_N PF08240.7 CEH18456.1 - 7.2e-15 54.6 2.3 1.6e-14 53.6 1.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEH18456.1 - 2.1e-13 49.9 0.0 4.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CEH18456.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MR_MLE_N PF02746.11 CEH18456.1 - 0.043 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1602 PF07673.9 CEH18457.1 - 1.1 8.8 6.5 1.1 8.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1602) LIP PF03583.9 CEH18458.1 - 4.6e-47 160.6 0.1 6e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 CEH18458.1 - 0.00079 18.6 0.9 0.85 8.7 0.0 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family FAD_binding_4 PF01565.18 CEH18459.1 - 5e-20 71.3 1.5 9.3e-20 70.5 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CEH18459.1 - 0.006 16.4 0.4 0.034 14.0 0.1 2.5 2 0 0 2 2 2 1 Berberine and berberine like Aldo_ket_red PF00248.16 CEH18460.1 - 1.7e-41 141.9 0.0 2e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MCM PF00493.18 CEH18463.1 - 1.1e-131 438.6 0.0 1.5e-131 438.1 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 CEH18463.1 - 1.6e-08 34.3 0.0 5.8e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CEH18463.1 - 5e-08 32.3 0.0 4.6e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CEH18463.1 - 7.1e-05 22.4 0.1 0.00084 18.9 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CEH18463.1 - 0.0022 17.4 0.1 0.84 9.0 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain HTH_20 PF12840.2 CEH18463.1 - 0.033 13.9 0.0 0.099 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain MCM_N PF14551.1 CEH18463.1 - 0.037 14.5 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 MCM N-terminal domain Cdc6_C PF09079.6 CEH18463.1 - 0.1 12.3 0.6 1.9 8.2 0.0 2.8 3 0 0 3 3 3 0 CDC6, C terminal AAA_32 PF13654.1 CEH18463.1 - 0.13 10.9 0.7 0.26 9.9 0.5 1.4 1 0 0 1 1 1 0 AAA domain GATase PF00117.23 CEH18464.1 - 5.1e-05 22.8 0.0 9.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CEH18464.1 - 0.049 13.0 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase C26 DUF4102 PF13356.1 CEH18464.1 - 0.054 13.3 0.0 7.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4102) HHH_2 PF12826.2 CEH18464.1 - 0.09 12.6 0.7 13 5.7 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif ATG16 PF08614.6 CEH18465.1 - 2.3e-38 131.9 9.8 3.1e-38 131.5 6.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CENP-H PF05837.7 CEH18465.1 - 0.056 13.6 14.1 0.31 11.2 2.2 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Exonuc_VII_L PF02601.10 CEH18465.1 - 1.1 8.3 11.8 1.8 7.6 8.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2962 PF11176.3 CEH18465.1 - 1.7 8.1 7.0 1.8 8.1 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2962) IncA PF04156.9 CEH18465.1 - 2.6 7.5 20.6 0.85 9.1 10.3 2.4 1 1 1 2 2 2 0 IncA protein HAUS6_N PF14661.1 CEH18465.1 - 3.6 6.8 13.5 2.2 7.5 2.3 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF972 PF06156.8 CEH18465.1 - 8.1 6.8 13.4 1.2 9.4 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Abhydrolase_3 PF07859.8 CEH18466.1 - 2.7e-23 82.6 0.6 2.4e-21 76.3 0.2 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CEH18466.1 - 2.1e-17 62.8 0.0 2.3e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 CEH18466.1 - 0.027 13.7 0.0 0.059 12.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Macoilin PF09726.4 CEH18467.1 - 8.1 4.5 6.0 8.5 4.5 4.2 1.0 1 0 0 1 1 1 0 Transmembrane protein PQ-loop PF04193.9 CEH18468.1 - 3.9e-24 83.9 4.2 9e-12 44.3 0.1 2.7 3 0 0 3 3 3 2 PQ loop repeat Ribosomal_L29 PF00831.18 CEH18468.1 - 0.081 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein SAM_PNT PF02198.11 CEH18469.1 - 0.0092 15.7 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain IGR PF09597.5 CEH18469.1 - 0.14 12.1 0.3 0.38 10.6 0.2 1.8 1 0 0 1 1 1 0 IGR protein motif 2OG-FeII_Oxy_2 PF13532.1 CEH18470.1 - 4.3e-11 43.0 0.1 8.4e-10 38.7 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CEH18470.1 - 0.0018 18.5 0.0 0.039 14.2 0.0 2.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily YebG PF07130.7 CEH18470.1 - 0.085 12.5 0.1 0.26 10.9 0.1 1.8 1 0 0 1 1 1 0 YebG protein BMFP PF04380.8 CEH18475.1 - 0.036 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Membrane fusogenic activity MerR-DNA-bind PF09278.6 CEH18476.1 - 0.093 13.1 13.9 0.35 11.3 3.2 3.8 3 0 0 3 3 3 0 MerR, DNA binding DCR PF14047.1 CEH18476.1 - 0.16 12.2 0.1 2.2e+02 2.2 0.0 4.0 4 0 0 4 4 4 0 Dppa2/4 conserved region MPC PF03650.8 CEH18480.1 - 4.1e-36 123.5 0.0 4.6e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) HAD_2 PF13419.1 CEH18481.1 - 0.021 15.0 0.1 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CEH18481.1 - 0.064 12.9 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 HAD-hyrolase-like P34-Arc PF04045.9 CEH18482.1 - 7.4e-95 316.8 0.2 2.1e-91 305.5 0.4 2.1 1 1 1 2 2 2 2 Arp2/3 complex, 34 kD subunit p34-Arc Ran_BP1 PF00638.13 CEH18483.1 - 1.4e-15 57.4 0.0 1e-07 32.0 0.0 2.2 2 0 0 2 2 2 2 RanBP1 domain WH1 PF00568.18 CEH18483.1 - 0.0057 16.3 0.0 3 7.6 0.0 2.4 2 1 0 2 2 2 2 WH1 domain MIP-T3 PF10243.4 CEH18483.1 - 0.64 8.4 18.8 0.83 8.0 13.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 CEH18483.1 - 0.88 7.9 18.3 1.1 7.6 12.7 1.1 1 0 0 1 1 1 0 Daxx Family Menin PF05053.8 CEH18483.1 - 7.4 4.6 12.0 35 2.3 8.4 1.8 2 0 0 2 2 2 0 Menin DUF2459 PF09601.5 CEH18484.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) RNA_pol_Rpb2_6 PF00562.23 CEH18485.1 - 1.2e-62 211.9 0.0 2.1e-62 211.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CEH18485.1 - 8.4e-60 201.1 0.4 1.2e-59 200.6 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CEH18485.1 - 7.4e-33 113.5 0.6 1.5e-32 112.5 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CEH18485.1 - 5.7e-29 100.2 0.1 1.5e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CEH18485.1 - 5.5e-24 83.7 1.0 1.4e-23 82.4 0.7 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CEH18485.1 - 1.7e-21 75.7 0.4 3.4e-20 71.5 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CEH18485.1 - 4.8e-13 48.8 0.4 1.4e-12 47.3 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L13 PF00572.13 CEH18486.1 - 9.5e-10 38.6 0.2 1.6e-09 37.8 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L13 DDRGK PF09756.4 CEH18486.1 - 0.065 12.6 0.1 0.12 11.8 0.0 1.5 1 1 1 2 2 2 0 DDRGK domain Ribosomal_L32e PF01655.13 CEH18487.1 - 2.5e-34 117.6 0.0 2.9e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_S3_C PF00189.15 CEH18488.1 - 7.3e-17 61.3 0.1 1.6e-16 60.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CEH18488.1 - 4.7e-13 48.4 0.0 8.2e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 CEH18488.1 - 0.01 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 ubiquitin PF00240.18 CEH18489.1 - 5.7e-35 118.5 0.7 8.2e-35 118.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CEH18489.1 - 4.4e-31 106.2 10.5 7e-31 105.5 7.3 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CEH18489.1 - 5.7e-20 70.7 0.7 8.8e-20 70.1 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CEH18489.1 - 7.5e-06 26.1 0.1 3e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CEH18489.1 - 0.00016 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CEH18489.1 - 0.0076 16.1 0.1 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CEH18489.1 - 0.014 15.5 0.1 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-DHHC PF01529.15 CEH18489.1 - 1.1 8.6 3.8 1.5 8.1 2.6 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Pex24p PF06398.6 CEH18490.1 - 2.8e-20 72.4 4.2 2.8e-20 72.4 2.9 2.3 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Opi1 PF08618.5 CEH18491.1 - 7.2e-128 427.1 1.6 8.2e-117 390.7 0.7 3.4 3 1 1 4 4 4 2 Transcription factor Opi1 REF PF05755.7 CEH18491.1 - 9.3e-05 22.2 0.0 0.63 9.7 0.0 2.7 3 0 0 3 3 3 2 Rubber elongation factor protein (REF) Perilipin PF03036.11 CEH18491.1 - 0.0014 17.5 10.2 0.054 12.3 0.0 3.2 4 0 0 4 4 4 2 Perilipin family COX4 PF02936.9 CEH18491.1 - 0.0048 16.6 1.7 0.0099 15.6 1.2 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Metaviral_G PF09595.5 CEH18492.1 - 0.023 14.3 2.7 0.03 13.9 1.8 1.3 1 0 0 1 1 1 0 Metaviral_G glycoprotein PH PF00169.24 CEH18493.1 - 0.00062 19.9 0.0 0.37 11.0 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 CEH18493.1 - 0.00078 19.5 0.0 0.065 13.3 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain CPSase_L_D2 PF02786.12 CEH18494.1 - 8.4e-83 276.8 0.2 1.4e-82 276.1 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CEH18494.1 - 5.4e-61 205.4 0.0 1e-60 204.5 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CEH18494.1 - 7.7e-36 122.5 0.0 2.4e-35 120.9 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HMGL-like PF00682.14 CEH18494.1 - 2.4e-29 102.6 0.0 4.7e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.14 CEH18494.1 - 1.1e-28 99.2 0.0 2.9e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CEH18494.1 - 4.1e-21 75.5 0.3 7.4e-21 74.7 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CEH18494.1 - 9.7e-18 63.5 1.3 2.1e-17 62.5 0.9 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CEH18494.1 - 2.3e-17 62.7 0.0 6.1e-17 61.3 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CEH18494.1 - 2.1e-16 59.3 5.0 2.8e-09 36.4 0.3 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 CEH18494.1 - 5.7e-11 42.1 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 CEH18494.1 - 3.3e-10 39.7 2.6 1.2e-05 24.8 0.2 2.4 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.17 CEH18494.1 - 5.3e-08 32.4 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CEH18494.1 - 1.3e-06 28.3 0.0 2.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CEH18494.1 - 1.7e-06 27.6 0.0 4.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 CEH18494.1 - 2.6e-05 24.5 0.6 0.044 14.1 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.14 CEH18494.1 - 5e-05 22.9 0.0 9.9e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.1 CEH18494.1 - 0.00016 21.3 0.4 0.00037 20.1 0.3 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 CEH18494.1 - 0.00036 20.2 1.1 0.0047 16.6 0.2 2.8 2 1 1 3 3 3 1 Glycine cleavage H-protein HlyD_2 PF12700.2 CEH18494.1 - 0.00039 19.6 0.4 0.42 9.7 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein NQRA PF05896.6 CEH18494.1 - 0.00059 19.1 0.7 0.00093 18.4 0.1 1.6 2 0 0 2 2 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.4 CEH18494.1 - 0.0061 16.2 0.1 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) DUF2789 PF10982.3 CEH18494.1 - 0.2 11.6 0.1 0.71 9.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) PEX11 PF05648.9 CEH18495.1 - 9e-16 57.8 0.0 1.1e-14 54.2 0.0 1.9 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DNA_ligase_A_M PF01068.16 CEH18496.1 - 4.3e-13 49.0 0.0 7.5e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 CEH18496.1 - 9e-06 25.2 0.1 1.9e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain DAGAT PF03982.8 CEH18497.1 - 3.3e-55 186.8 1.9 1.1e-40 139.2 0.1 2.7 1 1 1 2 2 2 2 Diacylglycerol acyltransferase DUF3429 PF11911.3 CEH18497.1 - 0.06 13.3 0.7 0.11 12.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) Tau95 PF09734.4 CEH18499.1 - 8.3e-51 173.1 0.0 1.1e-50 172.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit AIP3 PF03915.8 CEH18500.1 - 5.8e-98 328.5 0.0 1.2e-97 327.5 0.0 1.5 1 1 0 1 1 1 1 Actin interacting protein 3 Syntaxin-6_N PF09177.6 CEH18500.1 - 0.45 10.9 4.0 39 4.7 0.1 4.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF3317 PF11779.3 CEH18501.1 - 0.053 12.9 1.1 0.073 12.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) DUF1409 PF07197.7 CEH18503.1 - 0.033 14.2 0.1 0.078 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) Zn_clus PF00172.13 CEH18504.1 - 0.00021 21.1 8.6 0.00037 20.3 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 CEH18504.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.20 CEH18505.1 - 1.3e-37 129.3 0.0 6.7e-24 84.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH18505.1 - 6.1e-13 48.4 0.0 7.1e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CEH18505.1 - 0.0047 16.6 6.4 0.0096 15.6 3.7 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEH18505.1 - 0.01 14.7 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Kinase-like M_domain PF12938.2 CEH18509.1 - 0.13 12.0 4.3 0.12 12.1 1.6 1.8 2 0 0 2 2 2 0 M domain of GW182 Acyl-CoA_dh_1 PF00441.19 CEH18511.1 - 2.7e-50 170.3 1.5 4.1e-50 169.7 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEH18511.1 - 6.4e-25 86.4 0.5 1.7e-24 85.0 0.3 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CEH18511.1 - 2.1e-23 83.0 0.9 3.2e-23 82.4 0.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CEH18511.1 - 2e-17 63.6 1.1 3.5e-17 62.9 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CEH18511.1 - 0.0033 16.8 0.3 0.017 14.5 0.2 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short PF00106.20 CEH18512.1 - 5.9e-22 78.3 0.1 9e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH18512.1 - 5.3e-08 32.7 0.1 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CEH18512.1 - 0.0004 20.2 0.0 0.00055 19.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CEH18512.1 - 0.059 12.7 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CEH18512.1 - 0.067 13.1 0.1 0.42 10.6 0.0 2.1 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 CEH18512.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CBP PF12192.3 CEH18513.1 - 0.0031 17.4 0.2 0.0084 16.0 0.1 1.8 1 0 0 1 1 1 1 Fungal calcium binding protein ESSS PF10183.4 CEH18514.1 - 0.019 15.3 0.1 3.4 8.1 0.0 2.4 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pyrophosphatase PF00719.14 CEH18515.1 - 2.3e-58 196.0 0.6 9.9e-49 164.7 0.0 2.3 1 1 1 2 2 2 2 Inorganic pyrophosphatase Ribosomal_L6 PF00347.18 CEH18517.1 - 6.4e-15 55.4 0.0 4.3e-13 49.5 0.0 2.6 3 0 0 3 3 3 2 Ribosomal protein L6 LSM PF01423.17 CEH18518.1 - 1.9e-17 62.5 0.1 3.2e-17 61.8 0.1 1.3 1 1 0 1 1 1 1 LSM domain RNase_H2_suC PF08615.6 CEH18518.1 - 0.087 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) HPP PF04982.8 CEH18520.1 - 1.4e-33 115.2 8.1 2.2e-33 114.6 5.6 1.3 1 0 0 1 1 1 1 HPP family DUF3670 PF12419.3 CEH18521.1 - 0.018 14.4 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 SNF2 Helicase protein APC_CDC26 PF10471.4 CEH18521.1 - 0.86 10.3 0.1 0.86 10.3 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit 1 AICARFT_IMPCHas PF01808.13 CEH18522.1 - 3.7e-108 361.3 0.1 5e-108 360.8 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CEH18522.1 - 1.1e-20 73.3 0.0 2.3e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Invasin_D3 PF09134.5 CEH18522.1 - 0.024 14.4 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 Invasin, domain 3 Amidohydro_4 PF13147.1 CEH18523.1 - 0.00032 20.8 0.9 0.00044 20.3 0.6 1.2 1 0 0 1 1 1 1 Amidohydrolase Porin_4 PF13609.1 CEH18524.1 - 0.064 12.7 0.1 0.064 12.7 0.1 1.1 1 0 0 1 1 1 0 Gram-negative porin Fork_head PF00250.13 CEH18525.1 - 2.7e-30 104.2 0.0 5.3e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 Fork head domain CDP-OH_P_transf PF01066.16 CEH18527.1 - 1.2e-13 51.2 0.6 1.2e-13 51.2 0.4 2.9 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Utp11 PF03998.8 CEH18529.1 - 4.2e-59 200.2 8.8 5.3e-59 199.9 6.1 1.1 1 0 0 1 1 1 1 Utp11 protein Pox_RNA_Pol_19 PF05320.7 CEH18529.1 - 0.61 9.8 3.9 0.88 9.3 1.8 1.8 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DPBB_1 PF03330.13 CEH18530.1 - 2.4e-06 27.4 0.0 3.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel NRDE-2 PF08424.5 CEH18531.1 - 5.2e-50 170.1 0.8 3.7e-48 164.0 0.0 3.1 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 CEH18531.1 - 1.6 9.5 24.2 2.5 8.9 0.2 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat CN_hydrolase PF00795.17 CEH18532.1 - 1.5e-12 47.2 0.0 9.6e-12 44.6 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 CEH18533.1 - 6.8e-34 117.1 30.7 6.8e-34 117.1 21.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CEH18533.1 - 5.2e-06 25.1 15.4 0.00011 20.7 2.6 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 CEH18533.1 - 4.1e-05 22.3 27.6 0.00045 18.9 19.1 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter Plant_vir_prot PF01307.12 CEH18533.1 - 0.096 12.4 0.2 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 Plant viral movement protein Glyco_hydro_63 PF03200.11 CEH18534.1 - 1.1e-07 30.1 3.7 7.8e-07 27.3 0.4 3.5 4 1 0 4 4 4 1 Mannosyl oligosaccharide glucosidase CT47 PF15623.1 CEH18536.1 - 0.45 10.2 18.5 0.85 9.2 12.8 1.4 1 0 0 1 1 1 0 Cancer/testis gene family 47 PNPase PF03726.9 CEH18536.1 - 1.7 8.9 5.4 5.2 7.4 3.7 1.9 1 1 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Ribosomal_S13 PF00416.17 CEH18537.1 - 3.4e-41 140.0 1.4 4e-41 139.7 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CEH18537.1 - 0.0073 14.8 0.0 0.0075 14.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 CEH18537.1 - 0.021 14.8 0.1 0.069 13.2 0.0 1.9 1 1 0 2 2 2 0 Helix-hairpin-helix motif Rotavirus_VP1 PF12289.3 CEH18537.1 - 0.055 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Rotavirus VP1 structural protein Cullin PF00888.17 CEH18538.1 - 1.4e-143 479.5 0.2 1.4e-135 453.1 0.0 3.3 3 1 0 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.4 CEH18538.1 - 2.6e-29 100.8 1.2 6.5e-29 99.5 0.9 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Rrf2 PF02082.15 CEH18538.1 - 0.0044 17.1 0.0 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 Transcriptional regulator Myc_N PF01056.13 CEH18538.1 - 0.72 8.9 6.5 0.073 12.2 0.2 2.3 2 1 1 3 3 3 0 Myc amino-terminal region CNH PF00780.17 CEH18539.1 - 7.5e-64 215.8 0.0 1e-63 215.3 0.0 1.1 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 CEH18539.1 - 1.9e-11 44.0 0.0 3.9e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CEH18539.1 - 0.03 14.5 0.0 0.089 13.0 0.0 1.8 2 1 0 2 2 2 0 PH domain Homeobox PF00046.24 CEH18540.1 - 3.5e-11 42.5 9.5 7.9e-09 35.0 0.2 2.3 1 1 1 2 2 2 2 Homeobox domain CDC27 PF09507.5 CEH18541.1 - 5.1e-17 62.2 21.3 7.5e-17 61.6 12.7 2.0 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 eIF-3c_N PF05470.7 CEH18541.1 - 9 4.2 11.4 17 3.3 7.9 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DnaJ PF00226.26 CEH18542.1 - 2.6e-16 59.0 0.1 4.5e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 CEH18542.1 - 4.5e-12 45.2 0.0 8.3e-12 44.4 0.0 1.5 1 0 0 1 1 1 1 CSL zinc finger Sugar_tr PF00083.19 CEH18543.1 - 2.7e-68 230.6 27.1 1.9e-32 112.4 4.7 3.1 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 CEH18543.1 - 1.4e-12 47.0 41.0 4.4e-11 42.0 7.5 3.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 CEH18543.1 - 8.9 6.4 8.3 3.5 7.7 2.1 2.7 2 1 0 2 2 2 0 Phage holin family 2 COesterase PF00135.23 CEH18545.1 - 4.8e-74 249.9 0.0 7.8e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CEH18545.1 - 6.2e-08 32.4 0.8 0.00058 19.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pyrid_oxidase_2 PF13883.1 CEH18546.1 - 6.7e-17 61.7 0.3 1e-16 61.2 0.2 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NRDE-2 PF08424.5 CEH18546.1 - 0.048 12.5 2.1 0.058 12.2 1.4 1.0 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference ThiF PF00899.16 CEH18547.1 - 2.1e-05 24.3 0.0 0.00062 19.6 0.0 2.6 1 1 0 1 1 1 1 ThiF family Pkinase PF00069.20 CEH18548.1 - 4.7e-60 202.9 0.0 6.9e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH18548.1 - 7.9e-30 103.7 0.0 1.2e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CEH18548.1 - 0.00084 19.1 0.0 0.0036 17.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEH18548.1 - 0.018 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 CEH18548.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 CEH18548.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 CEH18548.1 - 0.22 10.5 0.0 0.4 9.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Clathrin PF00637.15 CEH18551.1 - 9.8e-182 595.8 19.4 2.3e-31 108.2 0.1 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 CEH18551.1 - 4.5e-36 120.6 1.9 0.0002 21.4 0.0 7.7 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 CEH18551.1 - 5.3e-32 109.5 0.2 1.6e-31 108.0 0.2 1.9 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 CEH18551.1 - 3.8e-10 38.5 0.8 7.9e-10 37.5 0.0 2.0 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 CEH18551.1 - 0.00088 18.1 3.0 0.21 10.3 0.0 4.0 4 0 0 4 4 4 1 Coatomer WD associated region TPR_2 PF07719.12 CEH18551.1 - 0.019 14.8 0.9 65 3.8 0.3 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEH18551.1 - 0.019 14.7 3.6 8.6 6.4 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEH18551.1 - 0.022 14.3 0.1 12 5.6 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEH18551.1 - 0.67 9.9 7.5 2.4 8.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 CEH18551.1 - 3.2 8.6 11.2 25 5.8 0.0 7.1 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF221 PF02714.10 CEH18554.1 - 3.7e-83 279.0 18.8 3.7e-83 279.0 13.0 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CEH18554.1 - 1e-21 77.1 0.0 1e-21 77.1 0.0 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CEH18554.1 - 1e-16 61.2 0.0 1.8e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Rad51 PF08423.6 CEH18555.1 - 1.4e-133 443.5 0.1 1.7e-133 443.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CEH18555.1 - 1.1e-12 47.8 0.0 1.5e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CEH18555.1 - 1.1e-09 37.8 0.1 1.5e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CEH18555.1 - 2.9e-09 36.9 0.1 5.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CEH18555.1 - 9.5e-08 31.4 0.0 1.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 KaiC PAXNEB PF05625.6 CEH18555.1 - 0.0032 16.3 0.4 0.021 13.6 0.4 1.8 1 1 1 2 2 2 1 PAXNEB protein HHH PF00633.18 CEH18555.1 - 0.0082 15.7 0.1 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif DnaB_C PF03796.10 CEH18555.1 - 0.06 12.2 0.1 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Spc97_Spc98 PF04130.8 CEH18556.1 - 3.8e-103 345.6 0.0 4.7e-103 345.3 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Nol1_Nop2_Fmu PF01189.12 CEH18561.1 - 5.1e-94 314.8 0.0 6.9e-94 314.3 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 CEH18561.1 - 0.00092 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 CEH18561.1 - 0.0027 17.7 0.0 0.007 16.3 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.14 CEH18561.1 - 0.025 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2962 PF11176.3 CEH18562.1 - 4.7e-31 107.4 6.3 5.8e-31 107.1 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DELLA PF12041.3 CEH18562.1 - 0.14 11.8 0.6 0.78 9.4 0.1 2.3 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal UPRTase PF14681.1 CEH18563.1 - 8.4e-77 257.0 0.0 9.7e-77 256.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CEH18563.1 - 9e-06 25.4 0.0 1.1e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain NmrA PF05368.8 CEH18564.1 - 2.4e-23 82.6 0.0 2.1e-22 79.5 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CEH18564.1 - 1.7e-10 41.1 0.0 2.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 CEH18564.1 - 4.2e-07 29.9 0.1 6.8e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 CEH18564.1 - 2.5e-05 23.8 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CEH18564.1 - 0.00013 20.8 0.1 0.00023 19.9 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 CEH18564.1 - 0.00032 21.0 0.4 0.0009 19.6 0.3 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 CEH18564.1 - 0.00078 19.8 0.1 0.021 15.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 CEH18564.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.5 CEH18564.1 - 0.0013 18.3 0.1 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 KR domain HI0933_like PF03486.9 CEH18564.1 - 0.0018 16.7 0.5 0.0067 14.9 0.0 1.8 1 1 1 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 CEH18564.1 - 0.003 17.7 0.1 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding adh_short PF00106.20 CEH18564.1 - 0.0035 17.2 0.2 0.006 16.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.11 CEH18564.1 - 0.0046 16.4 0.1 0.0083 15.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 CEH18564.1 - 0.0058 16.7 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 CEH18564.1 - 0.04 13.7 0.2 0.15 11.9 0.3 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 CEH18564.1 - 0.045 12.7 0.2 0.058 12.3 0.2 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 CEH18564.1 - 0.064 12.8 0.2 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 CEH18564.1 - 0.12 12.8 0.2 18 5.7 0.1 2.3 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain DAO PF01266.19 CEH18564.1 - 0.15 10.9 1.0 0.28 10.0 0.2 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase Rxt3 PF08642.5 CEH18565.1 - 2.8e-19 69.4 3.5 6.5e-19 68.2 0.0 2.9 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 CEH18565.1 - 0.0048 16.8 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 1 LCCL domain Spore_coat_CotO PF14153.1 CEH18565.1 - 0.82 9.0 10.3 1.8 7.9 7.2 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 CEH18565.1 - 0.93 7.1 0.5 1.3 6.6 0.4 1.1 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 CEH18565.1 - 6.9 6.4 9.3 16 5.2 6.5 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MFS_1 PF07690.11 CEH18566.1 - 1.8e-42 145.3 39.8 8.7e-40 136.5 29.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CEH18566.1 - 4.2e-22 78.0 17.1 5.5e-22 77.7 11.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CEH18566.1 - 6.5e-11 41.4 9.1 6.5e-11 41.4 6.3 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter CNH PF00780.17 CEH18567.1 - 1.2e-85 287.2 0.0 2.1e-85 286.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 CEH18567.1 - 2.6e-37 128.4 0.0 3.8e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 CEH18567.1 - 1.2e-34 119.2 0.0 5.4e-34 117.0 0.0 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.16 CEH18567.1 - 5.1e-12 45.3 0.0 9.8e-12 44.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MF_alpha PF04648.7 CEH18567.1 - 2.6 8.4 8.4 12 6.2 0.3 3.2 2 0 0 2 2 2 0 Yeast mating factor alpha hormone YjeF_N PF03853.10 CEH18569.1 - 9.9e-30 103.3 0.0 4e-29 101.3 0.0 1.8 2 0 0 2 2 2 1 YjeF-related protein N-terminus Germane PF10646.4 CEH18569.1 - 0.12 12.4 0.0 0.46 10.6 0.0 1.8 2 0 0 2 2 2 0 Sporulation and spore germination Peptidase_S24 PF00717.18 CEH18570.1 - 0.00023 20.7 0.0 0.15 11.7 0.0 2.5 2 1 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.4 CEH18570.1 - 0.00041 19.8 0.0 0.0038 16.7 0.0 2.5 2 1 0 2 2 2 1 Signal peptidase, peptidase S26 Methyltransf_PK PF05891.7 CEH18571.1 - 2.9e-48 164.0 0.0 5.1e-44 150.1 0.0 3.1 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 CEH18571.1 - 1.1e-06 28.4 0.0 3.9e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH18571.1 - 0.0012 19.2 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH18571.1 - 0.015 15.7 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF4589 PF15252.1 CEH18571.1 - 0.07 12.9 0.1 0.16 11.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) UBN2 PF14223.1 CEH18572.1 - 0.0083 15.9 0.0 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CEH18572.1 - 0.04 13.3 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) FWWh PF14922.1 CEH18572.1 - 0.093 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function SPA PF08616.5 CEH18573.1 - 9.4e-06 25.3 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.16 CEH18573.1 - 0.0032 17.1 0.6 0.016 14.8 0.0 2.4 3 0 0 3 3 3 1 DENN (AEX-3) domain Avl9 PF09794.4 CEH18573.1 - 0.012 14.0 0.0 2 6.7 0.0 2.2 2 0 0 2 2 2 0 Transport protein Avl9 Polysacc_synt_4 PF04669.8 CEH18574.1 - 5.8e-27 94.2 3.5 5.7e-26 91.0 2.4 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis HMG_box PF00505.14 CEH18575.1 - 8.8e-08 32.3 7.0 7.4e-06 26.1 1.4 2.7 3 0 0 3 3 3 2 HMG (high mobility group) box Abhydrolase_6 PF12697.2 CEH18576.1 - 0.0022 17.9 0.2 0.014 15.2 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH18576.1 - 0.0026 17.5 0.3 0.007 16.1 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CEH18576.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) GPI-anchored PF10342.4 CEH18577.1 - 8.8e-10 38.9 0.2 1.4e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CEH18577.1 - 0.026 13.9 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3304 PF11745.3 CEH18577.1 - 0.16 12.1 0.4 0.7 10.1 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3304) GATA PF00320.22 CEH18579.1 - 6.4e-29 99.0 16.7 1.7e-15 56.0 4.3 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CEH18579.1 - 0.0012 18.1 3.5 0.041 13.2 1.2 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 CEH18579.1 - 0.013 15.4 1.4 3.8 7.5 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain ETC_C1_NDUFA5 PF04716.9 CEH18581.1 - 1.4e-13 50.0 0.0 2.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Sds3 PF08598.6 CEH18582.1 - 3e-11 43.2 1.7 1.2e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Sds3-like Med3 PF11593.3 CEH18582.1 - 6.2 5.9 13.4 0.046 12.9 3.4 1.8 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Methyltransf_16 PF10294.4 CEH18583.1 - 3.3e-16 59.2 0.0 3.3e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CEH18583.1 - 0.049 14.2 0.1 0.14 12.7 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Glyco_trans_2_3 PF13632.1 CEH18586.1 - 8.1e-11 41.9 0.4 8.1e-11 41.9 0.3 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CEH18586.1 - 5e-06 26.4 1.1 9e-06 25.6 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CEH18586.1 - 0.017 14.8 0.1 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF2786 PF10979.3 CEH18586.1 - 0.21 11.3 0.9 0.44 10.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) O-antigen_lig PF13425.1 CEH18586.1 - 0.27 11.2 2.1 4.3 7.3 0.1 3.0 2 1 1 3 3 3 0 O-antigen ligase like membrane protein Cellulase PF00150.13 CEH18587.1 - 1.7e-24 86.4 0.1 2.4e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AAA PF00004.24 CEH18588.1 - 5.8e-97 320.9 0.0 4.7e-47 159.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CEH18588.1 - 2.5e-21 75.3 0.1 1.1e-20 73.3 0.0 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 CEH18588.1 - 1.6e-14 53.5 0.1 6.2e-06 25.4 0.0 3.5 3 1 1 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CEH18588.1 - 1.5e-13 50.9 0.0 2.7e-07 30.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CEH18588.1 - 3.6e-13 49.5 0.1 3e-06 27.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 CEH18588.1 - 2.4e-12 46.7 0.4 4.1e-06 26.5 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CEH18588.1 - 1.8e-11 44.2 0.3 0.0014 18.8 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CEH18588.1 - 2.8e-11 44.3 0.1 0.00067 20.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 CEH18588.1 - 6.6e-11 41.6 0.0 1.6e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 CEH18588.1 - 2e-10 40.9 0.1 0.00088 19.3 0.0 3.6 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 CEH18588.1 - 2.1e-09 36.6 0.1 0.0012 17.6 0.0 2.6 2 1 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 CEH18588.1 - 1.1e-08 34.6 3.3 0.0065 15.8 0.0 4.0 2 2 1 4 4 4 2 AAA domain Zeta_toxin PF06414.7 CEH18588.1 - 1.3e-08 34.1 0.0 0.0049 15.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 CEH18588.1 - 5.1e-08 32.5 0.0 0.0032 16.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 CEH18588.1 - 5.3e-08 32.8 0.0 0.0036 17.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 CEH18588.1 - 6.4e-08 32.0 0.4 0.0044 16.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CEH18588.1 - 1.3e-07 31.2 0.9 0.019 14.7 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 CEH18588.1 - 3.9e-07 30.2 0.0 0.013 15.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 CEH18588.1 - 1e-06 29.0 0.0 0.042 14.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.12 CEH18588.1 - 1.2e-06 27.5 0.1 0.0044 15.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 KaiC PF06745.8 CEH18588.1 - 1.6e-06 27.4 0.4 0.48 9.5 0.0 3.4 2 1 1 3 3 3 2 KaiC Vps4_C PF09336.5 CEH18588.1 - 2e-06 27.6 0.1 1.9e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.1 CEH18588.1 - 2.4e-06 27.2 0.0 0.067 12.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 CEH18588.1 - 2.8e-06 27.3 0.0 0.056 13.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 CEH18588.1 - 4.3e-06 26.6 0.0 0.0052 16.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 CEH18588.1 - 5.4e-06 25.5 0.0 0.0037 16.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 CEH18588.1 - 7.9e-06 25.4 0.0 0.28 10.6 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CEH18588.1 - 2.3e-05 24.4 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 CEH18588.1 - 2.3e-05 24.7 0.0 0.061 13.6 0.0 3.3 2 1 0 2 2 2 1 ABC transporter NACHT PF05729.7 CEH18588.1 - 2.4e-05 24.0 0.1 0.07 12.7 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Arch_ATPase PF01637.13 CEH18588.1 - 2.4e-05 24.1 0.0 1.8 8.2 0.0 3.5 2 1 1 3 3 3 1 Archaeal ATPase Bac_DnaA PF00308.13 CEH18588.1 - 3.7e-05 23.4 0.0 0.26 10.8 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein PhoH PF02562.11 CEH18588.1 - 7.2e-05 22.1 0.2 0.4 9.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 CEH18588.1 - 9.3e-05 22.0 0.0 0.42 10.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 CEH18588.1 - 0.00023 20.8 0.0 0.58 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CEH18588.1 - 0.00027 20.5 0.0 0.63 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CEH18588.1 - 0.00064 18.6 0.1 0.2 10.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.4 CEH18588.1 - 0.00087 18.3 0.0 0.91 8.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 CEH18588.1 - 0.001 18.6 0.0 0.12 11.8 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 CEH18588.1 - 0.0018 17.7 0.9 1.2 8.5 0.0 3.8 3 1 1 4 4 4 1 AAA-like domain NTPase_1 PF03266.10 CEH18588.1 - 0.0022 17.7 0.3 0.75 9.4 0.0 3.5 3 0 0 3 3 3 1 NTPase T2SE PF00437.15 CEH18588.1 - 0.0051 15.7 0.0 0.17 10.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein UPF0079 PF02367.12 CEH18588.1 - 0.018 14.6 0.1 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IPT PF01745.11 CEH18588.1 - 0.021 13.9 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 CEH18588.1 - 0.03 13.2 0.0 0.61 9.0 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain AFG1_ATPase PF03969.11 CEH18588.1 - 0.057 12.2 0.0 7.7 5.2 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_23 PF13476.1 CEH18588.1 - 0.062 13.6 0.0 0.93 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 CEH18588.1 - 0.067 13.0 0.4 7 6.4 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase DEAD PF00270.24 CEH18588.1 - 0.076 12.4 0.2 26 4.2 0.0 3.6 3 1 1 4 4 4 0 DEAD/DEAH box helicase KTI12 PF08433.5 CEH18588.1 - 0.079 12.1 0.0 4.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zot PF05707.7 CEH18588.1 - 0.084 12.3 0.2 12 5.2 0.1 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) PIF1 PF05970.9 CEH18588.1 - 0.14 11.0 0.0 4.7 6.0 0.0 2.7 2 0 0 2 2 2 0 PIF1-like helicase PPV_E1_C PF00519.12 CEH18588.1 - 0.14 10.7 0.1 1.4 7.4 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase PH PF00169.24 CEH18590.1 - 4.5e-08 33.2 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CEH18590.1 - 0.024 14.8 0.4 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain NIF PF03031.13 CEH18592.1 - 2.4e-46 157.2 0.0 2.8e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_L5_C PF00673.16 CEH18593.1 - 1.3e-22 79.3 0.0 1.9e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CEH18593.1 - 2.1e-20 72.2 0.1 5e-20 71.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 TatD_DNase PF01026.16 CEH18594.1 - 1.8e-47 161.6 0.0 2.3e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 CEH18594.1 - 0.0002 21.0 0.2 0.043 13.3 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase ACC_epsilon PF13822.1 CEH18594.1 - 2.4 8.5 0.0 2.4 8.5 0.0 3.2 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit DUF3986 PF13143.1 CEH18595.1 - 0.0028 18.0 0.1 39 4.7 0.0 4.7 3 1 2 5 5 5 0 Protein of unknown function (DUF3986) DUF4350 PF14258.1 CEH18595.1 - 0.013 15.7 0.0 2.1 8.6 0.0 3.9 2 1 3 5 5 5 0 Domain of unknown function (DUF4350) Fis1_TPR_N PF14852.1 CEH18595.1 - 0.076 12.3 0.1 49 3.3 0.0 3.9 4 0 0 4 4 4 0 Fis1 N-terminal tetratricopeptide repeat DUF3911 PF13050.1 CEH18595.1 - 0.082 13.0 0.4 13 6.0 0.0 4.4 4 2 1 5 5 5 0 Protein of unknown function (DUF3911) Pyr_redox_3 PF13738.1 CEH18596.1 - 3.6e-08 33.7 0.0 9.4e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CEH18596.1 - 8.3e-07 27.5 0.0 3e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CEH18596.1 - 9.5e-06 24.7 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CEH18596.1 - 0.002 18.0 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Gly_transf_sug PF04488.10 CEH18597.1 - 2.8e-08 34.0 0.0 7.3e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif CCDC144C PF14915.1 CEH18597.1 - 0.23 10.3 0.0 0.34 9.7 0.0 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region PgaD PF13994.1 CEH18598.1 - 0.0083 15.6 0.1 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 PgaD-like protein DUF2681 PF10883.3 CEH18598.1 - 0.029 14.5 0.3 0.076 13.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) IncA PF04156.9 CEH18598.1 - 0.041 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 IncA protein RdRP PF05183.7 CEH18599.1 - 4.8e-145 484.5 0.0 6.7e-145 484.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Zn_clus PF00172.13 CEH18600.1 - 4.5e-11 42.4 6.7 7.4e-11 41.7 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_20 PF00982.16 CEH18602.1 - 2.4e-185 616.5 0.0 5.5e-138 460.3 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 CEH18602.1 - 0.0082 15.5 0.1 4.8 6.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 His_Phos_1 PF00300.17 CEH18604.1 - 4.2e-14 52.9 0.1 8.4e-13 48.7 0.1 2.4 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Orn_Arg_deC_N PF02784.11 CEH18605.1 - 2.7e-68 229.8 0.0 3.7e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CEH18605.1 - 7.3e-28 96.6 0.0 1.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain E1-E2_ATPase PF00122.15 CEH18607.1 - 7.1e-22 77.5 0.6 4.8e-20 71.5 0.4 2.5 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CEH18607.1 - 7.7e-22 78.7 0.0 5.5e-21 75.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CEH18607.1 - 4.9e-19 69.2 0.9 1.2e-18 67.9 0.6 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEH18607.1 - 0.061 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PAT1 PF09770.4 CEH18608.1 - 2.3e-170 568.6 12.9 6e-170 567.2 8.9 1.6 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DEAD PF00270.24 CEH18610.1 - 5.3e-43 146.4 0.0 2.8e-42 144.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH18610.1 - 5.9e-27 93.3 0.1 1.2e-26 92.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH18610.1 - 0.0052 16.6 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CEH18610.1 - 0.095 11.0 0.0 0.18 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) hDGE_amylase PF14701.1 CEH18611.1 - 7.1e-156 519.3 0.0 1.1e-155 518.7 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CEH18611.1 - 1.4e-104 349.7 0.0 2.3e-104 349.0 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CEH18611.1 - 3.1e-78 262.5 0.0 4.6e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 CEH18611.1 - 1.4e-20 72.8 0.0 3e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 CEH18611.1 - 0.0015 18.0 0.8 0.7 9.2 0.0 2.7 3 0 0 3 3 3 2 Alpha amylase, catalytic domain GATA PF00320.22 CEH18614.1 - 3e-13 48.8 2.8 4.9e-13 48.1 1.9 1.4 1 0 0 1 1 1 1 GATA zinc finger Pex2_Pex12 PF04757.9 CEH18615.1 - 3.7e-22 78.8 3.0 5.2e-22 78.3 2.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 CEH18615.1 - 5.8e-10 38.8 7.7 9.1e-10 38.2 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEH18615.1 - 7.4e-08 32.2 7.5 1.2e-07 31.6 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH18615.1 - 8e-08 31.8 4.8 1.2e-07 31.3 3.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CEH18615.1 - 9.2e-08 32.0 2.3 1.5e-07 31.4 1.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CEH18615.1 - 2.2e-07 30.4 5.5 3.3e-07 29.8 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEH18615.1 - 4e-07 29.5 6.3 6.9e-07 28.8 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CEH18615.1 - 0.0018 17.9 1.9 0.0036 16.9 0.4 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CEH18615.1 - 0.0048 16.7 2.7 0.0048 16.7 1.9 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CEH18615.1 - 0.0085 15.9 3.5 0.016 15.0 2.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CEH18615.1 - 0.02 14.4 4.9 0.03 13.9 3.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 CEH18615.1 - 0.31 10.9 2.4 0.66 9.8 1.6 1.5 1 0 0 1 1 1 0 IBR domain Aminotran_3 PF00202.16 CEH18616.1 - 1.5e-76 257.4 0.0 1.8e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Abhydrolase_5 PF12695.2 CEH18617.1 - 0.00011 21.9 0.1 0.00016 21.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 CEH18617.1 - 0.0024 17.1 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 CEH18617.1 - 0.082 12.3 0.2 0.16 11.3 0.1 1.5 1 1 0 1 1 1 0 Putative esterase tRNA-synt_2b PF00587.20 CEH18620.1 - 6.7e-66 221.1 0.0 1.5e-65 220.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CEH18620.1 - 0.011 15.6 0.4 4.9 7.1 0.1 2.6 1 1 1 2 2 2 0 Anticodon binding domain Plectin PF00681.15 CEH18620.1 - 0.1 12.1 0.0 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 Plectin repeat Fis1_TPR_N PF14852.1 CEH18621.1 - 1.1e-13 50.2 0.1 2e-13 49.3 0.0 1.5 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat Fis1_TPR_C PF14853.1 CEH18621.1 - 3e-10 39.8 1.0 4.6e-10 39.2 0.7 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 CEH18621.1 - 0.0011 18.7 0.2 0.0031 17.3 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEH18621.1 - 0.056 14.1 0.0 0.095 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 CEH18621.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region ABC_membrane_2 PF06472.10 CEH18622.1 - 2.2e-100 335.4 1.1 3e-100 334.9 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CEH18622.1 - 3.5e-14 53.2 0.0 2.8e-13 50.3 0.0 2.5 3 0 0 3 3 3 1 ABC transporter AAA_17 PF13207.1 CEH18622.1 - 0.0022 18.8 0.0 0.0071 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEH18622.1 - 0.0069 15.4 0.0 0.019 14.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CEH18622.1 - 0.0071 16.5 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 CEH18622.1 - 0.0076 16.6 0.2 1.3 9.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CEH18622.1 - 0.0087 16.0 0.0 0.031 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 CEH18622.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 CEH18622.1 - 0.019 15.1 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CEH18622.1 - 0.021 14.2 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 CEH18622.1 - 0.038 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CEH18622.1 - 0.046 12.8 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF4279 PF14106.1 CEH18622.1 - 0.05 13.4 0.2 3.5 7.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) AAA_5 PF07728.9 CEH18622.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 CEH18622.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 CEH18622.1 - 0.14 11.7 0.1 0.82 9.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_12 PF13087.1 CEH18623.1 - 6.3e-34 117.1 0.0 1.4e-33 115.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CEH18623.1 - 1.2e-13 51.1 1.7 1.1e-12 48.0 0.0 3.1 2 2 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CEH18623.1 - 8.4e-09 35.0 0.8 4.2e-08 32.8 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 CEH18623.1 - 0.0031 16.5 0.1 0.019 13.9 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CEH18623.1 - 0.061 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF87 PF01935.12 CEH18623.1 - 4.4 7.0 3.6 9.8 5.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 G-gamma PF00631.17 CEH18626.1 - 0.057 13.1 0.3 0.058 13.1 0.2 1.1 1 0 0 1 1 1 0 GGL domain DUF1604 PF07713.8 CEH18627.1 - 3e-30 103.8 12.0 7.4e-27 92.9 2.3 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1604) G-patch PF01585.18 CEH18627.1 - 1.1e-05 25.1 0.3 4e-05 23.3 0.2 2.0 1 0 0 1 1 1 1 G-patch domain PAN_4 PF14295.1 CEH18628.1 - 0.0034 17.0 4.0 0.01 15.5 2.8 1.8 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 CEH18628.1 - 0.038 13.8 3.3 0.13 12.1 2.3 2.0 1 0 0 1 1 1 0 PAN-like domain DUF515 PF04415.7 CEH18628.1 - 2.3 6.3 20.8 1.6 6.8 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Pol_alpha_B_N PF08418.5 CEH18630.1 - 3 7.2 8.5 2.9 7.3 4.1 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal MFS_1 PF07690.11 CEH18632.1 - 6e-24 84.4 43.8 6e-24 84.4 30.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CEH18632.1 - 0.043 13.6 0.4 0.043 13.6 0.3 2.6 3 0 0 3 3 3 0 MFS_1 like family Gate PF07670.9 CEH18633.1 - 0.11 12.4 3.6 0.22 11.4 2.5 1.5 1 0 0 1 1 1 0 Nucleoside recognition DUF4293 PF14126.1 CEH18633.1 - 0.11 12.3 2.5 0.7 9.8 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Abhydrolase_6 PF12697.2 CEH18634.1 - 2e-23 83.4 2.5 2e-23 83.4 1.7 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH18634.1 - 2.7e-05 23.9 0.0 5.8e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH18634.1 - 0.0091 15.5 0.1 2.5 7.5 0.0 3.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold ketoacyl-synt PF00109.21 CEH18635.1 - 1.9e-51 175.0 0.9 3.6e-51 174.0 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 CEH18635.1 - 2.6e-40 138.0 0.4 9.9e-40 136.1 0.1 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 CEH18635.1 - 3.1e-40 138.4 1.1 6.1e-40 137.4 0.8 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 CEH18635.1 - 5.9e-37 127.4 1.5 5.9e-37 127.4 1.1 2.3 3 0 0 3 3 3 1 Polyketide synthase dehydratase adh_short PF00106.20 CEH18635.1 - 8.3e-36 123.4 0.5 3.2e-35 121.5 0.3 2.2 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 CEH18635.1 - 8.1e-32 109.5 0.2 3.3e-31 107.5 0.1 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 CEH18635.1 - 1.4e-10 41.7 0.4 9.7e-10 39.0 0.2 2.5 3 0 0 3 3 2 1 Thioesterase domain PP-binding PF00550.20 CEH18635.1 - 2.4e-07 30.8 0.2 5.3e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 CEH18635.1 - 4.5e-07 29.7 0.0 6.1e-06 26.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH18635.1 - 3.5e-05 24.3 0.0 0.00031 21.2 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain ACP_syn_III PF08545.5 CEH18635.1 - 0.0005 19.6 0.4 0.0036 16.9 0.3 2.5 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_31 PF13847.1 CEH18635.1 - 0.00053 19.6 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 CEH18635.1 - 0.011 14.6 0.0 0.027 13.4 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_12 PF08242.7 CEH18635.1 - 0.035 14.5 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 CEH18635.1 - 0.62 9.3 0.0 1.3 8.3 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain RVT_1 PF00078.22 CEH18636.1 - 6.5e-18 64.8 0.0 1.3e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM104 PF15434.1 CEH18637.1 - 0.61 10.3 4.2 0.72 10.0 2.9 1.2 1 0 0 1 1 1 0 Family 104 PI-PLC-X PF00388.14 CEH18641.1 - 2.1e-43 147.2 0.0 3.3e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CEH18641.1 - 8.2e-30 103.2 0.0 1.7e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 CEH18641.1 - 0.0025 17.6 0.4 0.048 13.5 0.1 2.7 2 1 0 2 2 2 1 C2 domain WAPL PF07814.8 CEH18643.1 - 6.5e-09 34.9 0.1 1.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DUF1860 PF08949.5 CEH18643.1 - 0.054 13.0 0.8 0.11 12.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) HSA PF07529.8 CEH18648.1 - 0.12 12.1 0.6 0.21 11.4 0.4 1.4 1 0 0 1 1 1 0 HSA TAFII28 PF04719.9 CEH18650.1 - 3.8e-20 71.4 0.3 3e-19 68.5 0.1 2.2 2 0 0 2 2 2 1 hTAFII28-like protein conserved region M-inducer_phosp PF06617.8 CEH18650.1 - 0.0012 18.0 1.3 0.0012 18.0 0.9 2.1 2 0 0 2 2 2 1 M-phase inducer phosphatase Tol_Tol_Ttg2 PF05494.7 CEH18650.1 - 0.0021 17.6 0.6 0.0032 17.0 0.4 1.3 1 0 0 1 1 1 1 Toluene tolerance, Ttg2 PBP1_TM PF14812.1 CEH18650.1 - 5.7 7.3 16.4 6.3 7.1 0.5 2.9 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GIY-YIG PF01541.19 CEH18651.1 - 0.0038 17.5 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-RING_2 PF13639.1 CEH18651.1 - 0.023 14.5 2.8 0.042 13.6 0.1 2.5 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.3 CEH18651.1 - 0.048 13.6 1.7 0.64 10.0 0.1 2.6 3 0 0 3 3 3 0 FANCL C-terminal domain TPR_11 PF13414.1 CEH18652.1 - 2.4e-51 171.2 34.9 3.8e-15 55.2 0.7 6.6 6 1 1 7 7 6 6 TPR repeat TPR_1 PF00515.23 CEH18652.1 - 2.4e-38 128.1 22.6 2.3e-06 26.9 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 CEH18652.1 - 8e-28 94.0 34.7 0.00043 19.9 0.0 9.8 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 CEH18652.1 - 6.4e-19 68.0 22.7 0.00024 21.6 0.0 6.8 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 CEH18652.1 - 1.1e-15 57.7 20.6 0.00015 21.9 2.3 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 CEH18652.1 - 1.1e-15 56.0 20.9 0.0018 17.9 0.1 9.3 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 CEH18652.1 - 6.1e-15 54.9 30.3 2.4e-11 43.4 2.0 6.6 4 3 2 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CEH18652.1 - 7.8e-12 44.7 22.3 1.2 9.9 0.0 9.3 5 3 5 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 CEH18652.1 - 5.1e-06 26.2 15.8 0.37 11.1 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CEH18652.1 - 2.6e-05 23.9 10.2 0.6 9.9 0.0 5.6 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CEH18652.1 - 9.3e-05 21.9 19.7 0.095 12.5 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEH18652.1 - 0.00022 21.4 15.9 9.3 6.9 0.0 7.9 7 1 0 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 CEH18652.1 - 0.00082 19.4 20.5 0.11 12.6 4.6 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF357 PF04010.8 CEH18652.1 - 0.075 12.7 3.4 0.16 11.6 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF357) Apc5 PF12862.2 CEH18652.1 - 0.087 12.6 4.2 0.095 12.5 0.7 2.6 3 0 0 3 3 2 0 Anaphase-promoting complex subunit 5 Gly_radical PF01228.16 CEH18652.1 - 0.65 10.3 3.3 1.8 8.9 0.1 3.1 3 1 0 3 3 3 0 Glycine radical NAD_binding_9 PF13454.1 CEH18653.1 - 0.0097 15.6 0.0 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CEH18653.1 - 0.035 13.9 0.0 1.4 8.7 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH18653.1 - 0.079 12.9 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MIP PF00230.15 CEH18654.1 - 4.6e-50 170.1 14.7 6.6e-50 169.6 10.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF3262 PF11660.3 CEH18654.1 - 0.82 9.8 9.3 0.041 13.9 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) DUF2456 PF10445.4 CEH18655.1 - 1.3e-16 60.2 0.2 2.7e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) DUF383 PF04063.9 CEH18656.1 - 7.4e-40 136.5 0.0 1.7e-39 135.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CEH18656.1 - 2e-19 68.8 1.4 2e-19 68.8 1.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF384) WD40 PF00400.27 CEH18657.1 - 1.5e-56 186.4 9.6 2.5e-09 36.6 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat SH3_2 PF07653.12 CEH18658.1 - 1.8e-07 30.5 0.0 3.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CEH18658.1 - 8.4e-05 22.0 0.0 0.00022 20.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEH18658.1 - 0.00023 20.5 0.1 0.045 13.1 0.0 2.4 2 0 0 2 2 2 2 SH3 domain Fasciclin PF02469.17 CEH18659.1 - 1.5e-29 102.5 0.1 6.2e-20 71.4 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain COPIIcoated_ERV PF07970.7 CEH18660.1 - 1.1e-36 126.6 0.0 1.8e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CEH18660.1 - 9.1e-20 70.4 0.0 1.6e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TFIIH_BTF_p62_N PF08567.6 CEH18660.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain DUF3357 PF11837.3 CEH18661.1 - 0.14 12.0 0.6 1.3 8.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Adaptin_N PF01602.15 CEH18663.1 - 2e-141 471.9 2.5 2.3e-141 471.6 1.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CEH18663.1 - 5.3e-18 65.4 0.1 1.1e-17 64.3 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CEH18663.1 - 1.1e-06 28.8 1.2 0.46 10.8 0.1 4.5 3 2 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CEH18663.1 - 0.0029 17.5 1.3 69 3.9 0.0 5.7 5 0 0 5 5 5 0 HEAT repeat TIP120 PF08623.5 CEH18663.1 - 0.011 15.2 2.7 0.024 14.2 0.1 2.7 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) EXOSC1 PF10447.4 CEH18663.1 - 0.013 15.4 0.4 0.63 10.0 0.1 2.7 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Cnd1 PF12717.2 CEH18663.1 - 0.048 13.5 2.9 0.15 11.9 0.6 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RTTN_N PF14726.1 CEH18663.1 - 0.061 13.8 0.2 0.31 11.6 0.0 2.4 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Proteasom_PSMB PF10508.4 CEH18663.1 - 0.22 9.7 3.4 0.25 9.5 1.0 2.1 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit DUF1361 PF07099.6 CEH18665.1 - 0.026 14.3 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) UPF0086 PF01868.11 CEH18666.1 - 1.6e-12 46.9 0.0 5.6e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function UPF0086 CPSF_A PF03178.10 CEH18667.1 - 1.8e-88 296.7 0.0 5.6e-88 295.1 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 CEH18667.1 - 1.8e-65 221.0 0.0 3e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 CEH18667.1 - 0.1 12.4 0.1 1.6 8.7 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat ApoC-I PF04691.7 CEH18669.1 - 0.053 13.2 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) PX PF00787.19 CEH18670.1 - 5.5e-22 77.6 0.7 1.2e-21 76.6 0.5 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CEH18670.1 - 6.9e-10 38.5 3.1 2.4e-06 27.0 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 CEH18670.1 - 0.017 14.6 0.3 0.039 13.4 0.0 1.7 2 0 0 2 2 2 0 BAR domain DUF848 PF05852.6 CEH18670.1 - 0.24 11.2 1.8 2.6 7.8 0.0 2.9 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Mito_carr PF00153.22 CEH18671.1 - 9.8e-29 98.9 6.2 3.9e-19 68.1 0.1 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein DUF566 PF04484.7 CEH18671.1 - 1.9 7.9 8.6 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF566) UQ_con PF00179.21 CEH18672.1 - 4.5e-46 155.7 0.0 5.4e-46 155.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEH18672.1 - 3.2e-05 23.6 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CEH18672.1 - 0.012 15.2 0.1 0.024 14.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CEH18672.1 - 0.052 13.4 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain DAHP_synth_1 PF00793.15 CEH18673.1 - 1.4e-91 305.9 0.0 1.7e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF3536 PF12055.3 CEH18673.1 - 0.062 12.4 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) Pkinase PF00069.20 CEH18674.1 - 5.7e-70 235.4 0.0 8.5e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH18674.1 - 3.9e-26 91.6 0.0 6.6e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase IF-2B PF01008.12 CEH18675.1 - 2.6e-47 161.1 0.1 3e-47 160.9 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family FliG_C PF01706.11 CEH18675.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 FliG C-terminal domain Sterol_MT_C PF08498.5 CEH18676.1 - 2.1e-28 98.0 0.6 3e-28 97.5 0.4 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 CEH18676.1 - 1.6e-19 70.1 0.0 2.8e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH18676.1 - 6.2e-19 68.0 0.0 8.3e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH18676.1 - 3e-16 59.5 0.0 4.6e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CEH18676.1 - 7.5e-14 51.4 0.0 1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CEH18676.1 - 2.3e-12 47.5 0.0 7e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH18676.1 - 5.7e-12 45.8 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH18676.1 - 3.4e-11 43.4 0.0 9.8e-11 42.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH18676.1 - 3.1e-10 40.0 0.0 8.5e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEH18676.1 - 1.7e-07 30.6 0.0 2.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 CEH18676.1 - 8.5e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.12 CEH18676.1 - 7.1e-05 21.9 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_15 PF09445.5 CEH18676.1 - 7.2e-05 22.3 0.1 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 CEH18676.1 - 0.0003 20.1 0.0 0.00056 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 CEH18676.1 - 0.00082 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 CEH18676.1 - 0.0034 17.0 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CEH18676.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 CEH18676.1 - 0.033 15.0 0.0 0.09 13.6 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Met_10 PF02475.11 CEH18676.1 - 0.043 13.4 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_29 PF03141.11 CEH18676.1 - 0.043 12.1 0.0 0.071 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.8 CEH18676.1 - 0.046 12.8 0.0 0.098 11.7 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) PX PF00787.19 CEH18677.1 - 1.8e-11 43.8 0.0 3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 CEH18677.1 - 7.9e-09 35.0 5.8 1.3e-08 34.3 4.0 1.4 1 0 0 1 1 1 1 SNARE domain MFS_1 PF07690.11 CEH18678.1 - 1.2e-28 99.9 21.3 1.2e-28 99.9 14.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily PAP2_C PF14360.1 CEH18678.1 - 3.5 7.9 9.7 7.9 6.8 1.9 3.0 2 0 0 2 2 2 0 PAP2 superfamily C-terminal rve PF00665.21 CEH18679.1 - 4.6e-21 75.1 0.0 1.3e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DDE_3 PF13358.1 CEH18679.1 - 0.024 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_IS240 PF13610.1 CEH18679.1 - 0.026 14.4 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 DDE domain rve_3 PF13683.1 CEH18679.1 - 0.062 12.8 0.0 0.54 9.8 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain Pro_isomerase PF00160.16 CEH18682.1 - 2e-42 145.0 0.0 5.8e-42 143.5 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 CEH18682.1 - 7.6e-08 31.8 0.2 5.4e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger BLYB PF05289.6 CEH18683.1 - 0.014 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein EssA PF10661.4 CEH18684.1 - 0.042 13.5 0.1 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA RCR PF12273.3 CEH18686.1 - 0.079 13.5 0.0 0.1 13.1 0.0 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DivIC PF04977.10 CEH18688.1 - 0.00062 19.2 21.0 0.024 14.0 5.4 2.7 1 1 2 3 3 3 2 Septum formation initiator HALZ PF02183.13 CEH18688.1 - 0.0012 18.5 11.9 0.04 13.6 3.0 3.0 1 1 2 3 3 3 2 Homeobox associated leucine zipper Rab5-bind PF09311.6 CEH18688.1 - 0.0016 18.3 9.0 0.0021 17.9 6.3 1.1 1 0 0 1 1 1 1 Rabaptin-like protein Glyco_hydro_77 PF02446.12 CEH18688.1 - 0.0033 16.0 1.4 0.0039 15.8 1.0 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase FUSC PF04632.7 CEH18688.1 - 0.037 12.4 0.4 0.046 12.1 0.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GAGA_bind PF06217.7 CEH18688.1 - 0.04 13.8 5.8 0.054 13.4 4.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF904 PF06005.7 CEH18688.1 - 0.045 14.0 6.8 0.045 14.0 4.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 CEH18688.1 - 0.049 14.0 0.1 0.049 14.0 0.1 2.8 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.6 CEH18688.1 - 0.089 12.6 14.4 0.14 11.9 0.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MRP-L47 PF06984.8 CEH18688.1 - 0.14 12.0 7.2 4.1 7.3 4.2 2.6 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Nup54 PF13874.1 CEH18688.1 - 0.15 11.6 15.0 0.024 14.3 6.9 1.8 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 TSC22 PF01166.13 CEH18688.1 - 0.38 10.7 6.3 4.4 7.3 0.4 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family APG6 PF04111.7 CEH18688.1 - 0.6 9.0 10.8 0.85 8.6 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 CEH18688.1 - 0.91 9.4 21.6 0.3 10.9 12.2 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.6 CEH18688.1 - 1.1 9.2 18.1 0.042 13.8 7.1 2.0 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF972 PF06156.8 CEH18688.1 - 1.9 8.8 14.9 23 5.3 10.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Halogen_Hydrol PF10112.4 CEH18688.1 - 2.1 7.6 10.2 0.066 12.6 1.6 2.1 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Tropomyosin_1 PF12718.2 CEH18688.1 - 2.8 7.7 16.8 6.8 6.5 11.6 1.5 1 1 0 1 1 1 0 Tropomyosin like CENP-H PF05837.7 CEH18688.1 - 5.6 7.1 15.9 1.9 8.7 7.7 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Herpes_BLRF2 PF05812.7 CEH18689.1 - 0.00049 19.9 0.6 0.00049 19.9 0.4 2.4 2 1 0 2 2 2 1 Herpesvirus BLRF2 protein CCDC92 PF14916.1 CEH18689.1 - 0.00066 19.2 0.7 0.0014 18.1 0.5 1.7 1 1 0 1 1 1 1 Coiled-coil domain of unknown function Mod_r PF07200.8 CEH18689.1 - 0.0018 18.1 6.0 0.0018 18.1 4.2 1.4 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein HALZ PF02183.13 CEH18689.1 - 0.0037 16.9 1.8 0.0079 15.8 1.2 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper ADIP PF11559.3 CEH18689.1 - 0.0058 16.5 6.7 0.0058 16.5 4.6 2.0 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding IncA PF04156.9 CEH18689.1 - 0.025 14.1 4.7 0.031 13.8 3.2 1.3 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 CEH18689.1 - 0.028 14.7 2.9 0.028 14.7 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF641 PF04859.7 CEH18689.1 - 0.062 13.0 5.5 0.057 13.1 2.9 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) GAGA_bind PF06217.7 CEH18689.1 - 0.075 12.9 6.9 0.085 12.8 4.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TSC22 PF01166.13 CEH18689.1 - 0.15 12.0 2.2 0.46 10.4 0.4 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family ATG16 PF08614.6 CEH18689.1 - 0.19 11.5 11.6 0.4 10.4 7.8 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Macoilin PF09726.4 CEH18689.1 - 0.22 9.7 7.9 0.25 9.5 5.5 1.0 1 0 0 1 1 1 0 Transmembrane protein SlyX PF04102.7 CEH18689.1 - 0.31 11.4 5.4 5.6 7.4 3.7 2.4 1 1 0 1 1 1 0 SlyX Mnd1 PF03962.10 CEH18689.1 - 0.32 10.6 9.9 0.58 9.7 6.8 1.6 1 1 0 1 1 1 0 Mnd1 family DivIC PF04977.10 CEH18689.1 - 0.34 10.4 14.6 0.23 10.9 1.1 3.0 1 1 2 3 3 3 0 Septum formation initiator MHC2-interact PF09307.5 CEH18689.1 - 0.49 10.2 3.2 0.97 9.2 0.3 2.3 1 1 1 2 2 2 0 CLIP, MHC2 interacting Phage_Gp23 PF10669.4 CEH18689.1 - 0.5 10.4 4.2 0.32 11.1 1.8 1.5 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) LMBR1 PF04791.11 CEH18689.1 - 0.68 8.4 3.0 0.75 8.3 2.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein bZIP_1 PF00170.16 CEH18689.1 - 2.2 8.3 11.1 0.11 12.5 2.1 2.5 2 1 1 3 3 3 0 bZIP transcription factor CENP-Q PF13094.1 CEH18689.1 - 2.3 8.1 10.8 0.22 11.5 4.5 1.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF16 PF01519.11 CEH18689.1 - 3.2 8.0 6.8 6.2 7.1 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 Med9 PF07544.8 CEH18689.1 - 3.3 7.5 9.5 0.72 9.6 0.6 3.0 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4200 PF13863.1 CEH18689.1 - 4.7 7.1 12.7 93 2.9 8.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 CEH18689.1 - 6.1 6.7 16.4 2.1 8.1 3.3 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding PI31_Prot_C PF08577.6 CEH18690.1 - 0.0017 18.9 8.8 0.0017 18.9 6.1 2.3 2 0 0 2 2 2 1 PI31 proteasome regulator Lgl_C PF08596.5 CEH18691.1 - 2.6e-14 52.5 0.1 1.2e-09 37.1 0.0 3.0 3 0 0 3 3 3 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CEH18691.1 - 0.007 16.2 4.5 0.064 13.1 0.2 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF3312 PF11768.3 CEH18691.1 - 0.03 12.5 0.0 0.09 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Mt_ATP-synt_B PF05405.9 CEH18692.1 - 0.32 10.4 4.1 0.21 11.0 1.6 1.6 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Autophagy_N PF03986.8 CEH18693.1 - 3.1e-38 130.8 1.9 3.6e-22 78.7 0.1 3.2 3 1 0 3 3 3 2 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CEH18693.1 - 3.5e-28 97.5 0.2 6.1e-28 96.7 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CEH18693.1 - 2.6e-13 48.8 0.3 4.2e-13 48.1 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Meth_synt_2 PF01717.13 CEH18694.1 - 1.8e-16 60.0 0.0 3.2e-15 55.9 0.0 2.0 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain zf-HC2 PF13490.1 CEH18694.1 - 0.086 12.8 0.2 0.33 10.9 0.1 2.0 1 0 0 1 1 1 0 Putative zinc-finger Thiolase_C PF02803.13 CEH18695.1 - 5.5e-43 145.3 0.1 8e-43 144.7 0.1 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 CEH18695.1 - 1.4e-32 112.6 0.1 2.4e-32 111.9 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain PALP PF00291.20 CEH18696.1 - 2.4e-31 109.1 0.1 3.6e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IBR PF01485.16 CEH18697.1 - 2.8e-10 39.8 17.1 1.6e-09 37.4 6.5 3.1 3 0 0 3 3 3 3 IBR domain PGAP1 PF07819.8 CEH18698.1 - 2e-53 181.2 0.0 3e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CEH18698.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CEH18698.1 - 0.0042 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 CEH18698.1 - 0.0047 16.8 10.4 0.019 14.8 5.6 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 CEH18698.1 - 0.012 14.7 0.0 0.027 13.5 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 CEH18698.1 - 0.055 13.0 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 CEH18698.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 CEH18698.1 - 0.084 13.0 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain FCH PF00611.18 CEH18699.1 - 2.3e-15 56.5 0.6 8e-15 54.8 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 CEH18699.1 - 4.6e-11 41.9 0.3 8.7e-11 41.0 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CEH18699.1 - 1.7e-09 37.0 0.0 2.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CEH18699.1 - 2.2e-06 27.0 0.0 4.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Transcrip_act PF04949.8 CEH18699.1 - 0.26 10.8 2.4 0.6 9.7 0.2 2.1 1 1 0 2 2 2 0 Transcriptional activator TPR_MLP1_2 PF07926.7 CEH18699.1 - 8 6.2 10.0 1.5 8.5 4.0 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein She9_MDM33 PF05546.6 CEH18700.1 - 5.2e-43 147.0 4.7 5.7e-43 146.9 3.3 1.0 1 0 0 1 1 1 1 She9 / Mdm33 family DUF1133 PF06576.6 CEH18700.1 - 0.0069 15.5 0.4 0.008 15.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1133) Cas_Cas02710 PF09670.5 CEH18700.1 - 0.0099 14.5 4.0 0.013 14.2 2.8 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas02710) Pex19 PF04614.7 CEH18700.1 - 0.061 12.9 0.5 0.092 12.3 0.3 1.3 1 1 0 1 1 1 0 Pex19 protein family Uds1 PF15456.1 CEH18700.1 - 2.5 8.1 12.1 4.1 7.4 8.4 1.4 1 1 0 1 1 1 0 Up-regulated During Septation NDUFA12 PF05071.11 CEH18701.1 - 2.4e-09 37.5 1.1 3.7e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 FAD_binding_4 PF01565.18 CEH18701.1 - 0.076 12.4 0.8 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain 4HBT_3 PF13622.1 CEH18702.1 - 3.7e-20 72.7 0.6 1.3e-18 67.6 0.4 2.1 1 1 0 1 1 1 1 Thioesterase-like superfamily Cu2_monooxygen PF01082.15 CEH18702.1 - 0.0082 16.1 0.3 3.3 7.6 0.1 2.5 3 0 0 3 3 3 2 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DUF3046 PF11248.3 CEH18702.1 - 0.026 14.4 0.1 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) AAA_5 PF07728.9 CEH18703.1 - 9.2e-59 197.1 0.0 1.2e-25 89.8 0.0 4.1 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 CEH18703.1 - 9.2e-05 22.6 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Sof1 PF04158.9 CEH18703.1 - 0.066 13.2 0.3 0.17 11.9 0.2 1.8 1 0 0 1 1 1 0 Sof1-like domain Peptidase_C97 PF05903.9 CEH18704.1 - 8.4e-17 61.3 0.0 1.8e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 PPPDE putative peptidase domain Thioredoxin PF00085.15 CEH18705.1 - 1.6e-31 108.0 0.1 1.8e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CEH18705.1 - 2.1e-09 37.5 0.1 1.2e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEH18705.1 - 1.4e-07 31.5 0.0 2.2e-05 24.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CEH18705.1 - 8.9e-07 28.5 0.1 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CEH18705.1 - 4.7e-05 23.0 0.0 0.0026 17.4 0.0 2.0 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CEH18705.1 - 8.2e-05 22.1 0.1 0.0062 16.0 0.0 2.1 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 CEH18705.1 - 0.00047 20.1 0.0 0.00064 19.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like DUF2847 PF11009.3 CEH18705.1 - 0.0017 17.9 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Glutaredoxin PF00462.19 CEH18705.1 - 0.0077 16.1 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin HyaE PF07449.6 CEH18705.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE NTS_2 PF15448.1 CEH18705.1 - 0.045 14.0 0.0 4.6 7.6 0.0 2.4 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein Thioredoxin_3 PF13192.1 CEH18705.1 - 0.051 13.3 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.1 CEH18705.1 - 0.054 13.5 0.1 0.14 12.1 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin Cpl-7 PF08230.6 CEH18705.1 - 0.11 12.1 0.1 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 Cpl-7 lysozyme C-terminal domain DIM1 PF02966.11 CEH18705.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 zf-H2C2_2 PF13465.1 CEH18707.1 - 1.1e-13 50.6 12.8 3.5e-06 27.0 0.1 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CEH18707.1 - 4.2e-11 42.3 15.0 0.0021 18.2 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CEH18707.1 - 6.7e-10 38.7 20.3 0.00013 22.0 2.0 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CEH18707.1 - 6.9e-06 26.0 3.8 0.77 9.9 0.0 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CEH18707.1 - 0.014 15.2 2.9 0.65 9.9 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 CEH18707.1 - 0.38 10.5 0.0 0.38 10.5 0.0 2.8 3 0 0 3 3 3 0 BED zinc finger zf-met PF12874.2 CEH18707.1 - 0.5 10.6 5.3 4.3 7.6 0.0 3.7 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CEH18707.1 - 4.1 7.8 5.3 3 8.2 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Abhydrolase_5 PF12695.2 CEH18708.1 - 1.7e-12 47.2 0.0 3.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH18708.1 - 1.3e-10 41.5 0.5 2.1e-10 40.8 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CEH18708.1 - 2.7e-06 27.1 0.1 4.9e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CEH18708.1 - 0.022 14.9 0.0 0.045 13.9 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain Peptidase_S15 PF02129.13 CEH18708.1 - 0.031 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 CEH18708.1 - 0.043 13.6 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase UNC-93 PF05978.11 CEH18709.1 - 7.9e-06 25.4 2.8 7.9e-06 25.4 1.9 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Asp PF00026.18 CEH18710.1 - 1.6e-34 119.5 10.5 5.5e-34 117.8 7.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CEH18710.1 - 9.3e-07 29.2 3.7 0.0042 17.5 0.6 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 CEH18710.1 - 0.019 14.9 0.3 0.019 14.9 0.2 2.2 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CEH18710.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Acetyltransf_1 PF00583.19 CEH18711.1 - 3.5e-09 36.5 0.0 4.2e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEH18711.1 - 1.7e-05 24.8 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEH18711.1 - 0.00012 21.7 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CEH18711.1 - 0.00031 20.8 0.0 0.00036 20.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CEH18711.1 - 0.001 18.9 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4149 PF13664.1 CEH18712.1 - 2.1e-18 66.2 0.3 2.1e-18 66.2 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) RGS PF00615.14 CEH18713.1 - 2e-12 47.2 0.0 1.9e-07 31.2 0.0 2.4 2 1 0 2 2 2 2 Regulator of G protein signaling domain Metallophos_2 PF12850.2 CEH18714.1 - 5.2e-20 71.8 0.1 7.9e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CEH18714.1 - 3.6e-05 23.2 3.8 0.011 15.0 0.1 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase MFMR PF07777.6 CEH18714.1 - 0.0056 16.6 1.9 0.0081 16.1 1.3 1.2 1 0 0 1 1 1 1 G-box binding protein MFMR CDC27 PF09507.5 CEH18714.1 - 0.91 8.6 17.9 1.2 8.2 12.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ycf1 PF05758.7 CEH18714.1 - 6.3 4.3 4.9 7.4 4.1 3.4 1.0 1 0 0 1 1 1 0 Ycf1 NIPSNAP PF07978.8 CEH18715.1 - 2.2e-34 117.4 1.2 1e-24 86.4 0.1 2.2 2 0 0 2 2 2 2 NIPSNAP DUF1754 PF08555.5 CEH18717.1 - 0.025 15.1 0.6 0.045 14.3 0.4 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) GATA PF00320.22 CEH18718.1 - 6.9 6.1 7.6 2.5 7.5 0.2 2.6 2 1 0 2 2 2 0 GATA zinc finger Antibiotic_NAT PF02522.9 CEH18720.1 - 0.016 14.4 0.1 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase AMP-binding PF00501.23 CEH18723.1 - 1.2e-62 211.6 0.0 1.5e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEH18723.1 - 1.5e-08 35.4 0.0 1.1e-07 32.6 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ELO PF01151.13 CEH18725.1 - 1.9e-55 187.8 15.1 2.4e-55 187.5 10.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2236 PF09995.4 CEH18725.1 - 0.02 14.1 0.0 0.046 13.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) DUF4532 PF15046.1 CEH18730.1 - 0.0044 16.0 0.3 0.0051 15.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4532) bZIP_1 PF00170.16 CEH18731.1 - 8.1e-08 32.1 6.1 1.5e-07 31.2 4.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEH18731.1 - 4.8e-06 26.2 4.3 4.8e-06 26.2 3.0 2.2 1 1 1 2 2 2 2 Basic region leucine zipper V_ATPase_I PF01496.14 CEH18731.1 - 0.011 13.6 0.4 0.015 13.2 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CASP_C PF08172.7 CEH18731.1 - 0.014 14.4 1.5 0.029 13.4 1.0 1.6 1 0 0 1 1 1 0 CASP C terminal HIGH_NTase1 PF05636.6 CEH18731.1 - 0.017 14.1 0.5 0.028 13.4 0.3 1.3 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase KLRAQ PF10205.4 CEH18731.1 - 0.034 14.1 3.7 0.11 12.5 2.6 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.12 CEH18731.1 - 0.098 12.9 4.0 0.24 11.7 2.8 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor BCAS2 PF05700.6 CEH18731.1 - 0.16 11.4 5.8 0.3 10.5 4.0 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Phage_GP20 PF06810.6 CEH18731.1 - 0.33 10.3 4.3 0.55 9.6 3.0 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Macoilin PF09726.4 CEH18731.1 - 1.4 7.1 13.4 0.14 10.3 6.0 1.5 1 1 0 1 1 1 0 Transmembrane protein IncA PF04156.9 CEH18731.1 - 2.9 7.4 8.1 5.5 6.5 5.6 1.4 1 0 0 1 1 1 0 IncA protein TTL PF03133.10 CEH18732.1 - 3.4e-44 150.9 0.0 1.3e-43 149.0 0.0 1.7 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 CEH18732.1 - 0.004 16.9 0.0 0.0071 16.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PhyH PF05721.8 CEH18733.1 - 1e-08 35.5 0.0 2.8e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) ATP-synt_E PF05680.7 CEH18734.1 - 2e-14 53.2 0.3 2.4e-14 53.0 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain MAGE_N PF12440.3 CEH18734.1 - 0.094 13.0 0.4 0.11 12.8 0.3 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal SspP PF08179.7 CEH18735.1 - 0.18 12.0 0.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 Small acid-soluble spore protein P family Metallophos PF00149.23 CEH18736.1 - 1.1e-40 139.2 0.1 1.4e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cupin_8 PF13621.1 CEH18739.1 - 1e-29 103.7 0.0 1.2e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CEH18739.1 - 1.2e-06 27.9 0.1 3e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 CEH18739.1 - 0.00013 22.2 0.0 0.00041 20.5 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 CEH18739.1 - 0.035 13.6 0.2 0.078 12.4 0.0 1.6 2 0 0 2 2 2 0 Cupin domain DnaJ PF00226.26 CEH18741.1 - 7.6e-15 54.3 1.5 1.4e-14 53.5 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain DivIC PF04977.10 CEH18741.1 - 0.057 12.9 1.9 0.13 11.7 1.3 1.6 1 0 0 1 1 1 0 Septum formation initiator DnaJ PF00226.26 CEH18742.1 - 1.6e-13 50.1 0.0 3.4e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Draxin PF15550.1 CEH18742.1 - 0.59 9.7 9.3 0.96 9.0 6.5 1.2 1 0 0 1 1 1 0 Draxin EMP24_GP25L PF01105.19 CEH18743.1 - 4.4e-38 130.8 0.0 5.2e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD adh_short PF00106.20 CEH18744.1 - 3.1e-32 111.7 0.3 4.3e-32 111.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH18744.1 - 8.6e-19 67.8 0.2 1.2e-18 67.4 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CEH18744.1 - 1.6e-11 44.4 0.0 2e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CEH18744.1 - 0.0012 18.8 1.1 0.0053 16.7 0.8 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CEH18744.1 - 0.0018 17.7 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CEH18744.1 - 0.0025 17.0 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 CEH18744.1 - 0.07 12.9 0.2 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Noc2 PF03715.8 CEH18745.1 - 1.3e-107 359.1 0.0 3e-107 357.9 0.0 1.6 1 0 0 1 1 1 1 Noc2p family TFIIA PF03153.8 CEH18745.1 - 0.00024 21.1 2.1 0.00024 21.1 1.5 2.9 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit NAD_binding_8 PF13450.1 CEH18746.1 - 7.1e-09 35.5 0.3 1.3e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CEH18746.1 - 1.7e-06 27.4 0.0 9.9e-06 24.8 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 CEH18746.1 - 3.6e-06 27.1 0.2 0.0003 20.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEH18746.1 - 5.4e-05 23.1 0.0 0.042 13.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEH18746.1 - 0.0027 17.4 0.1 0.23 11.2 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 CEH18746.1 - 0.11 11.3 0.0 0.78 8.5 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 CEH18746.1 - 0.13 10.6 0.2 0.32 9.4 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein MTP18 PF10558.4 CEH18749.1 - 5.8e-53 178.7 0.1 8.7e-53 178.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Baculo_p26 PF04766.7 CEH18749.1 - 0.09 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein Solute_trans_a PF03619.11 CEH18750.1 - 4.2e-80 268.9 3.6 5.1e-80 268.7 2.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha HsbA PF12296.3 CEH18752.1 - 5.6e-19 68.2 6.8 5.6e-19 68.2 4.7 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A UPRTase PF14681.1 CEH18754.1 - 2.4e-44 151.0 0.1 1.9e-41 141.5 0.0 2.1 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase Phosphoesterase PF04185.9 CEH18755.1 - 9.4e-22 77.7 4.0 1.6e-21 76.9 2.8 1.4 1 1 0 1 1 1 1 Phosphoesterase family Rhomboid_SP PF12595.3 CEH18755.1 - 0.076 12.6 0.2 0.71 9.4 0.0 2.1 2 0 0 2 2 2 0 Rhomboid serine protease Cu-oxidase_3 PF07732.10 CEH18756.1 - 7.7e-41 138.5 2.7 2.9e-39 133.4 0.3 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 CEH18756.1 - 6.3e-29 100.2 2.8 8.6e-26 90.0 0.0 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 CEH18756.1 - 1.1e-26 93.5 0.0 3.1e-26 92.1 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase HAD PF12710.2 CEH18757.1 - 2.9e-12 47.1 0.0 4e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 CEH18757.1 - 1.9e-07 30.6 2.9 1.1e-06 28.1 1.3 2.3 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 CEH18757.1 - 6.8e-05 22.1 1.1 0.00014 21.1 0.3 1.7 2 0 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.1 CEH18757.1 - 0.0007 19.8 0.0 0.0025 18.0 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase SAC3_GANP PF03399.11 CEH18758.1 - 5.1e-22 78.4 0.0 7e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CEH18758.1 - 5.1e-21 74.9 0.0 3.1e-20 72.4 0.0 2.0 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 Ribosomal_S4Pg PF11993.3 CEH18758.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) Fungal_trans PF04082.13 CEH18760.1 - 6.6e-19 67.7 0.0 1.9e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CEH18760.1 - 8.7e-10 38.3 9.3 1.5e-09 37.5 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Usp PF00582.21 CEH18761.1 - 1.5e-19 70.5 0.1 1.5e-19 70.5 0.1 2.7 2 0 0 2 2 2 1 Universal stress protein family Cellulase PF00150.13 CEH18762.1 - 3.6e-18 65.7 0.2 5.4e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DEAD PF00270.24 CEH18763.1 - 9e-16 57.8 0.0 3.2e-15 56.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH18763.1 - 0.00027 20.7 0.0 0.00071 19.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BRO1 PF03097.13 CEH18764.1 - 3.6e-96 322.1 0.0 2.1e-74 250.5 0.0 2.7 2 1 1 3 3 3 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CEH18764.1 - 3e-60 203.6 12.2 5.2e-60 202.9 8.5 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Med5 PF08689.5 CEH18765.1 - 2.3e-27 95.1 0.0 3.6e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit Med5 PK PF00224.16 CEH18766.1 - 1.1e-165 550.4 13.6 6.9e-100 334.0 2.6 2.1 1 1 1 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.11 CEH18766.1 - 3.8e-30 103.8 0.0 9.9e-30 102.4 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CEH18766.1 - 8.6e-06 24.7 1.6 0.005 15.7 1.1 2.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 CEH18766.1 - 0.0033 16.3 0.2 0.054 12.3 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Phage_Gp15 PF06854.6 CEH18766.1 - 0.026 14.0 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Gp15 protein APG9 PF04109.11 CEH18767.1 - 4.3e-154 512.8 1.5 6.2e-154 512.3 1.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 SURF4 PF02077.10 CEH18768.1 - 1.4e-95 319.7 2.9 1.5e-95 319.5 2.0 1.0 1 0 0 1 1 1 1 SURF4 family RRM_1 PF00076.17 CEH18769.1 - 3.5e-21 74.6 0.0 3.2e-12 45.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH18769.1 - 1.8e-16 59.8 0.0 1.8e-09 37.4 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH18769.1 - 0.0038 17.0 0.0 3.8 7.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ala_racemase_C PF00842.16 CEH18769.1 - 0.14 11.6 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain GMC_oxred_N PF00732.14 CEH18770.1 - 1.1e-65 221.7 0.1 1.5e-65 221.3 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CEH18770.1 - 6.4e-32 110.8 0.0 2.1e-31 109.1 0.0 1.9 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CEH18770.1 - 1.1e-05 24.5 3.2 0.00012 21.0 0.1 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CEH18770.1 - 2.2e-05 24.3 0.1 6.3e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CEH18770.1 - 4.8e-05 23.5 0.2 0.08 12.9 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CEH18770.1 - 0.00042 20.2 0.2 0.0076 16.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CEH18770.1 - 0.00069 18.5 5.9 0.0035 16.2 0.9 2.5 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 CEH18770.1 - 0.00086 18.3 0.0 0.00086 18.3 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 CEH18770.1 - 0.015 15.0 0.3 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 CEH18770.1 - 0.018 14.1 0.3 0.033 13.2 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Peptidase_M16 PF00675.15 CEH18771.1 - 2.2e-40 137.8 1.1 5e-40 136.6 0.0 2.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CEH18771.1 - 3.3e-31 108.3 0.0 8.2e-20 71.2 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain PXA PF02194.10 CEH18772.1 - 6.3e-32 110.6 0.0 2e-31 109.0 0.0 1.9 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 CEH18772.1 - 2.2e-22 79.2 0.1 1.8e-21 76.2 0.0 2.7 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 CEH18772.1 - 2.8e-12 46.4 0.0 5.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 PX domain LytR_cpsA_psr PF03816.9 CEH18772.1 - 0.0015 18.4 0.0 0.0048 16.8 0.0 1.8 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain RGS PF00615.14 CEH18772.1 - 0.04 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Regulator of G protein signaling domain ADH_N PF08240.7 CEH18773.1 - 2.8e-18 65.6 0.8 5.7e-18 64.6 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CEH18773.1 - 4e-10 39.3 0.0 3.4e-07 29.8 0.0 2.6 1 1 1 2 2 2 2 Zinc-binding dehydrogenase Pyr_redox PF00070.22 CEH18773.1 - 0.0038 17.5 0.1 0.07 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 CEH18773.1 - 0.014 14.5 0.0 0.052 12.7 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 CEH18773.1 - 0.021 15.1 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain ADH_zinc_N_2 PF13602.1 CEH18773.1 - 0.069 14.0 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.11 CEH18773.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 CEH18773.1 - 0.23 11.3 2.1 6.1 6.6 0.5 2.4 2 0 0 2 2 2 0 ThiF family Cyclin_N PF00134.18 CEH18775.1 - 1e-14 54.2 0.0 1.6e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CEH18775.1 - 2.3e-12 47.5 0.0 3.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin Metallophos PF00149.23 CEH18778.1 - 3e-08 33.3 5.4 7.8e-08 31.9 3.8 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CEH18778.1 - 1.8e-07 31.0 0.8 9.6e-07 28.7 0.5 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Kinesin PF00225.18 CEH18779.1 - 3.1e-107 358.1 0.3 7.8e-107 356.8 0.2 1.7 1 0 0 1 1 1 1 Kinesin motor domain DUF3037 PF11236.3 CEH18779.1 - 0.27 11.2 4.3 2.5 8.1 0.3 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) G_glu_transpept PF01019.16 CEH18781.1 - 4.4e-131 437.8 0.8 5.3e-131 437.5 0.6 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase IBR PF01485.16 CEH18782.1 - 5.6e-22 77.3 40.8 2.8e-12 46.3 2.2 4.4 4 1 1 5 5 5 3 IBR domain zf-C3HC4 PF00097.20 CEH18782.1 - 0.00011 21.7 1.0 0.00011 21.7 0.7 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEH18782.1 - 0.0012 18.6 3.6 0.0012 18.6 2.5 3.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CEH18782.1 - 0.0058 16.6 3.1 0.0058 16.6 2.1 4.7 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH18782.1 - 0.013 15.2 3.9 0.013 15.2 2.7 4.0 3 1 1 4 4 4 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CEH18782.1 - 0.055 13.3 0.5 0.055 13.3 0.3 4.3 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING DUF1488 PF07369.6 CEH18782.1 - 0.25 11.1 2.5 2.6 7.9 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1488) DUF1793 PF08760.6 CEH18783.1 - 9.9e-57 191.5 0.1 2.1e-56 190.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Ctr PF04145.10 CEH18784.1 - 1.3e-31 109.6 0.1 2.9e-31 108.4 0.0 1.5 1 1 0 1 1 1 1 Ctr copper transporter family PsbL PF02419.12 CEH18784.1 - 0.087 12.2 1.4 0.2 11.1 1.0 1.6 1 0 0 1 1 1 0 PsbL protein F-box PF00646.28 CEH18785.1 - 0.00032 20.2 0.7 0.0017 17.9 0.1 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CEH18785.1 - 0.033 13.9 0.7 0.071 12.8 0.1 1.9 2 0 0 2 2 2 0 F-box-like p450 PF00067.17 CEH18787.1 - 4.7e-58 196.8 0.0 7.9e-58 196.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF3043 PF11241.3 CEH18787.1 - 0.086 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Sec39 PF08314.6 CEH18788.1 - 1e-42 146.0 0.1 8.1e-42 143.0 0.0 1.9 2 0 0 2 2 2 2 Secretory pathway protein Sec39 GRAM PF02893.15 CEH18790.1 - 6.4e-15 54.4 0.0 1.3e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 GRAM domain MFS_1 PF07690.11 CEH18791.1 - 1.3e-29 103.0 38.4 1.6e-18 66.5 5.7 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH18791.1 - 3.1e-19 68.9 15.7 3.4e-18 65.4 0.2 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 CEH18791.1 - 0.029 12.4 4.2 0.062 11.3 3.0 1.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 CEH18791.1 - 0.045 13.7 3.5 2.6 8.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) RRM_1 PF00076.17 CEH18793.1 - 4.6e-38 128.6 1.5 6.1e-22 77.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH18793.1 - 3.3e-30 103.8 0.3 1.2e-16 60.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH18793.1 - 1.8e-18 66.1 0.1 2.8e-08 33.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 CEH18793.1 - 2.1e-17 63.1 0.1 5.7e-17 61.7 0.1 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Limkain-b1 PF11608.3 CEH18793.1 - 0.0095 15.6 0.1 0.0095 15.6 0.1 3.2 3 0 0 3 3 3 1 Limkain b1 Prefoldin_2 PF01920.15 CEH18794.1 - 7e-19 67.5 5.4 8.2e-19 67.3 3.7 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF812 PF05667.6 CEH18794.1 - 8.2e-05 21.3 3.1 0.0001 21.0 2.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF812) Poty_PP PF08440.5 CEH18794.1 - 0.00032 19.8 0.5 0.00033 19.8 0.3 1.0 1 0 0 1 1 1 1 Potyviridae polyprotein EzrA PF06160.7 CEH18794.1 - 0.0012 17.1 6.2 0.036 12.2 0.4 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA DASH_Dad3 PF08656.5 CEH18794.1 - 0.0015 18.2 2.2 0.0067 16.0 0.1 2.1 2 0 0 2 2 2 1 DASH complex subunit Dad3 FlaC_arch PF05377.6 CEH18794.1 - 0.0031 17.3 0.9 0.042 13.7 0.1 2.1 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Prefoldin PF02996.12 CEH18794.1 - 0.0098 15.5 5.8 0.19 11.3 0.7 2.2 1 1 1 2 2 2 2 Prefoldin subunit TBPIP PF07106.8 CEH18794.1 - 0.04 13.4 3.7 1.6 8.2 0.1 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3150 PF11348.3 CEH18794.1 - 0.041 12.9 0.1 0.066 12.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3150) DUF1640 PF07798.6 CEH18794.1 - 0.041 13.9 0.1 0.55 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) IncA PF04156.9 CEH18794.1 - 0.048 13.2 8.8 0.6 9.6 6.1 1.9 1 1 0 1 1 1 0 IncA protein CDC37_N PF03234.9 CEH18794.1 - 0.05 13.9 1.4 0.058 13.7 1.0 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding AAA_13 PF13166.1 CEH18794.1 - 0.051 12.0 0.5 0.058 11.8 0.4 1.1 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 CEH18794.1 - 0.055 13.8 4.2 3.4 8.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4404 PF14357.1 CEH18794.1 - 0.076 13.4 4.5 1.1 9.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TMF_TATA_bd PF12325.3 CEH18794.1 - 0.081 12.6 6.0 0.27 10.9 4.2 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 CEH18794.1 - 0.14 11.3 4.6 1.2 8.2 3.1 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding WXG100 PF06013.7 CEH18794.1 - 0.17 11.9 2.5 8.7 6.4 0.1 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG V-ATPase_C PF03223.10 CEH18794.1 - 0.17 10.7 1.2 1.9 7.3 0.1 1.9 1 1 1 2 2 2 0 V-ATPase subunit C DUF4140 PF13600.1 CEH18794.1 - 0.2 12.1 5.8 1.6 9.1 0.6 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 CEH18794.1 - 0.25 9.1 2.6 0.46 8.2 1.8 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 CEH18794.1 - 0.31 11.1 3.0 0.76 9.8 2.1 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 CEH18794.1 - 0.31 10.8 6.7 0.67 9.8 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 CEH18794.1 - 0.32 10.8 7.5 0.78 9.5 0.4 2.1 1 1 1 2 2 2 0 Tropomyosin like IFT57 PF10498.4 CEH18794.1 - 0.36 9.5 6.0 1 8.0 0.7 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.4 CEH18794.1 - 0.36 10.9 4.7 2.7 8.1 0.3 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIVA PF05103.8 CEH18794.1 - 0.39 10.7 7.4 0.2 11.6 0.3 2.0 2 0 0 2 2 2 0 DivIVA protein Apolipoprotein PF01442.13 CEH18794.1 - 0.47 9.9 8.2 2.3 7.6 5.7 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Nup54 PF13874.1 CEH18794.1 - 0.52 9.9 3.8 0.86 9.2 2.6 1.4 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Cortex-I_coil PF09304.5 CEH18794.1 - 0.66 10.0 4.3 0.41 10.6 0.3 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil NTR2 PF15458.1 CEH18794.1 - 0.78 8.9 6.1 5.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Nineteen complex-related protein 2 TPR_MLP1_2 PF07926.7 CEH18794.1 - 1 9.1 7.5 1.9 8.2 0.5 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.17 CEH18794.1 - 1.7 8.7 6.0 1.9 8.5 0.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF641 PF04859.7 CEH18794.1 - 1.7 8.4 6.4 3.9 7.2 0.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.16 CEH18794.1 - 1.8 8.5 4.9 5.3 7.0 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor APG6 PF04111.7 CEH18794.1 - 4.7 6.1 8.2 3.4 6.6 0.6 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Rho_Binding PF08912.6 CEH18794.1 - 6.1 7.2 7.1 2.2 8.6 1.4 2.2 2 0 0 2 2 2 0 Rho Binding Ank_5 PF13857.1 CEH18795.1 - 0.0097 16.1 0.0 0.053 13.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CEH18795.1 - 0.011 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.1 CEH18795.1 - 0.012 15.8 0.0 0.04 14.1 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.2 CEH18795.1 - 0.05 13.9 0.0 0.13 12.6 0.0 1.6 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CEH18795.1 - 0.051 14.1 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Dopey_N PF04118.9 CEH18796.1 - 6e-110 366.8 0.0 1.1e-109 365.9 0.0 1.4 1 0 0 1 1 1 1 Dopey, N-terminal Velvet PF11754.3 CEH18798.1 - 7.7e-21 74.6 0.8 3.6e-20 72.4 0.6 1.9 1 1 0 1 1 1 1 Velvet factor Prenyltrans PF00432.16 CEH18799.1 - 4.7e-28 96.4 10.6 2e-08 33.6 0.1 6.0 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CEH18799.1 - 2.2e-15 57.0 0.0 5.8e-12 46.0 0.0 3.6 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 CEH18799.1 - 0.023 14.7 0.0 0.48 10.4 0.0 2.4 1 1 0 1 1 1 0 Prenyltransferase-like MutS_V PF00488.16 CEH18800.1 - 7.4e-62 208.8 0.0 1.4e-61 207.8 0.0 1.5 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 CEH18800.1 - 2.5e-32 112.3 4.2 2.5e-32 112.3 2.9 1.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 CEH18800.1 - 1e-07 32.0 0.0 0.00026 21.0 0.0 2.6 2 0 0 2 2 2 2 MutS domain II AAA_14 PF13173.1 CEH18800.1 - 0.0045 16.8 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain MutS_IV PF05190.13 CEH18800.1 - 0.006 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_22 PF13401.1 CEH18800.1 - 0.014 15.5 0.3 0.15 12.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 CEH18800.1 - 0.18 12.0 0.4 0.45 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain p450 PF00067.17 CEH18801.1 - 1.7e-60 204.8 0.0 2.9e-41 141.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Kelch_4 PF13418.1 CEH18802.1 - 2.7e-18 65.4 17.5 5e-07 29.3 0.0 6.6 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CEH18802.1 - 2.1e-08 34.0 30.3 0.0025 17.9 0.2 7.9 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CEH18802.1 - 4.2e-07 29.8 7.0 0.17 12.1 0.0 5.9 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 CEH18802.1 - 6.2e-05 22.8 15.0 0.0076 16.1 0.0 6.1 7 1 0 7 7 7 2 Kelch motif Kelch_1 PF01344.20 CEH18802.1 - 0.0012 18.3 1.4 4.8 6.8 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CEH18802.1 - 0.044 13.5 3.1 18 5.3 0.0 4.4 4 0 0 4 4 4 0 Kelch motif Tox-WTIP PF15654.1 CEH18802.1 - 6.9 6.3 9.1 6.7 6.4 0.4 3.5 3 0 0 3 3 3 0 Toxin with a conserved tryptophan and TIP tripeptide motif HAD PF12710.2 CEH18803.1 - 1.1e-14 55.0 0.0 2.9e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CEH18803.1 - 3.8e-14 52.2 0.0 1.2e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CEH18803.1 - 1.2e-11 45.4 0.3 1.3e-06 29.0 0.0 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CEH18803.1 - 1.8e-11 43.8 0.0 5.8e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CEH18803.1 - 0.00038 20.1 0.5 0.0056 16.2 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2749 PF10907.3 CEH18803.1 - 0.28 11.0 1.7 0.58 10.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) RhoGAP PF00620.22 CEH18808.1 - 1.8e-38 131.5 0.0 3.3e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 CEH18808.1 - 2.4e-05 24.4 0.0 5.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain AAA_3 PF07726.6 CEH18808.1 - 0.027 14.0 0.0 0.073 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma70_ner PF04546.8 CEH18810.1 - 0.11 12.0 3.2 0.38 10.3 1.5 2.0 1 1 0 2 2 2 0 Sigma-70, non-essential region SSF PF00474.12 CEH18811.1 - 6.7e-11 41.4 20.1 9.1e-11 41.0 12.7 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family Spore_permease PF03845.8 CEH18811.1 - 0.00017 20.3 5.5 0.00043 19.0 3.8 1.6 1 0 0 1 1 1 1 Spore germination protein adh_short_C2 PF13561.1 CEH18812.1 - 9.6e-33 113.9 0.0 1.2e-32 113.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEH18812.1 - 6e-15 55.5 0.0 7.5e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH18812.1 - 6.4e-06 25.9 0.0 9.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Oxidored_nitro PF00148.14 CEH18812.1 - 0.027 13.1 0.0 0.037 12.6 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Epimerase PF01370.16 CEH18812.1 - 0.044 13.2 0.0 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 CEH18812.1 - 0.053 12.6 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Wax2_C PF12076.3 CEH18812.1 - 0.13 11.9 0.0 12 5.5 0.0 2.1 2 0 0 2 2 2 0 WAX2 C-terminal domain NMO PF03060.10 CEH18813.1 - 7.9e-71 238.8 0.5 9.4e-71 238.6 0.4 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CEH18813.1 - 1.7e-07 30.5 0.7 3.9e-07 29.2 0.5 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CEH18813.1 - 0.00045 19.1 0.8 0.00072 18.4 0.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PNPOx_C PF10590.4 CEH18814.1 - 1.1e-16 59.9 1.0 2.1e-16 59.1 0.7 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 CEH18814.1 - 2.2e-15 56.4 0.0 4.1e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cellulase PF00150.13 CEH18815.1 - 6.3e-19 68.2 2.0 1.3e-18 67.2 1.4 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glycos_transf_1 PF00534.15 CEH18816.1 - 6.1e-30 103.8 0.0 2.4e-29 101.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CEH18816.1 - 1e-14 54.9 0.5 4.6e-14 52.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CEH18816.1 - 2e-13 50.4 0.0 3.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CEH18816.1 - 2.8e-12 46.9 0.0 6.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CEH18816.1 - 0.00036 20.7 3.6 0.093 13.0 0.0 3.4 2 1 1 3 3 3 1 Glycosyl transferases group 1 Ank_2 PF12796.2 CEH18817.1 - 1.6e-23 82.8 1.1 1.3e-11 44.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CEH18817.1 - 1.9e-19 68.3 8.8 1.5e-09 37.1 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CEH18817.1 - 3.1e-17 62.5 6.5 2.4e-09 37.4 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CEH18817.1 - 8.1e-14 50.3 1.8 5.7e-05 22.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CEH18817.1 - 1.9e-12 46.9 7.1 8.5e-06 25.8 0.1 4.5 2 2 2 4 4 4 2 Ankyrin repeats (many copies) TFIIE_beta PF02186.10 CEH18818.1 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 TFIIE beta subunit core domain Rot1 PF10681.4 CEH18819.1 - 3.1e-48 163.9 3.7 3.1e-48 163.9 2.5 1.9 2 1 0 2 2 2 1 Chaperone for protein-folding within the ER, fungal DUF4231 PF14015.1 CEH18819.1 - 0.073 13.0 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Ribosomal_S21 PF01165.15 CEH18820.1 - 6e-10 38.4 2.5 1.1e-09 37.5 1.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 CobT PF06213.7 CEH18821.1 - 0.0027 16.8 17.6 0.0029 16.7 12.2 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 CEH18821.1 - 0.0091 15.6 14.9 0.011 15.3 10.3 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region NOA36 PF06524.7 CEH18821.1 - 0.016 14.4 16.2 0.019 14.2 11.2 1.1 1 0 0 1 1 1 0 NOA36 protein Merozoite_SPAM PF07133.6 CEH18821.1 - 0.023 14.5 17.0 0.025 14.4 11.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Daxx PF03344.10 CEH18821.1 - 0.11 11.0 18.9 0.12 10.8 13.1 1.0 1 0 0 1 1 1 0 Daxx Family Adaptin_binding PF10199.4 CEH18821.1 - 0.17 12.1 12.1 0.23 11.7 8.4 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF2457 PF10446.4 CEH18821.1 - 0.23 10.1 21.5 0.25 10.0 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4045 PF13254.1 CEH18821.1 - 0.46 9.7 5.1 0.49 9.6 3.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BTV_NS2 PF04514.7 CEH18821.1 - 0.47 9.2 5.8 0.5 9.1 4.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FYDLN_acid PF09538.5 CEH18821.1 - 0.54 10.8 16.6 0.69 10.5 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pox_Ag35 PF03286.9 CEH18821.1 - 0.95 8.9 9.3 1.1 8.7 6.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 CEH18821.1 - 2.3 6.0 19.3 2.3 6.0 13.4 1.0 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 CEH18821.1 - 2.4 7.8 14.9 3.2 7.3 10.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-T PF15511.1 CEH18821.1 - 2.4 7.3 13.7 3 6.9 9.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1754 PF08555.5 CEH18821.1 - 2.7 8.6 11.2 3.6 8.2 7.8 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) RRN3 PF05327.6 CEH18821.1 - 3.1 5.7 12.1 3.7 5.5 8.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Upf2 PF04050.9 CEH18821.1 - 4.1 7.1 15.6 5.1 6.8 10.8 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 CDC45 PF02724.9 CEH18821.1 - 4.1 5.3 13.1 4.4 5.2 9.1 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 CEH18821.1 - 5.2 6.2 18.9 6.3 5.9 13.1 1.2 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.5 CEH18821.1 - 5.9 6.8 9.4 7 6.6 6.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.7 CEH18821.1 - 6 5.1 19.1 6.7 4.9 13.2 1.0 1 0 0 1 1 1 0 Mpp10 protein Astro_capsid PF03115.9 CEH18821.1 - 6.3 4.9 7.5 6.7 4.8 5.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor BUD22 PF09073.5 CEH18821.1 - 8.7 5.2 18.2 9.4 5.1 12.6 1.1 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 CEH18821.1 - 8.7 5.6 15.5 9.8 5.4 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 CEH18821.1 - 9.1 4.8 13.6 9.8 4.7 9.4 1.1 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.11 CEH18821.1 - 9.7 5.0 13.3 12 4.7 9.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ebp2 PF05890.7 CEH18822.1 - 8.6e-68 228.5 4.3 1.1e-67 228.2 3.0 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF4391 PF14335.1 CEH18822.1 - 0.011 15.1 0.4 0.013 14.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) IncFII_repA PF02387.10 CEH18822.1 - 6.5 5.8 7.6 9 5.3 5.3 1.1 1 0 0 1 1 1 0 IncFII RepA protein family DUF619 PF04768.8 CEH18823.1 - 1e-31 109.6 0.0 2.5e-21 75.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF619) CAML PF14963.1 CEH18823.1 - 0.18 11.1 0.9 0.27 10.5 0.6 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand RsbU_N PF08673.5 CEH18824.1 - 0.077 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain GRAB PF10375.4 CEH18825.1 - 2.5e-07 30.0 0.7 2.5e-07 30.0 0.5 2.4 2 0 0 2 2 2 1 GRIP-related Arf-binding domain GRIP PF01465.15 CEH18825.1 - 0.00059 19.2 0.1 0.0014 18.1 0.1 1.6 1 0 0 1 1 1 1 GRIP domain SlyX PF04102.7 CEH18825.1 - 0.018 15.3 1.2 0.018 15.3 0.8 4.0 4 1 1 5 5 5 0 SlyX DUF904 PF06005.7 CEH18825.1 - 0.055 13.7 1.2 0.055 13.7 0.8 4.9 2 1 0 3 3 3 0 Protein of unknown function (DUF904) Spc42p PF11544.3 CEH18825.1 - 0.4 10.6 8.1 0.097 12.6 0.6 3.0 2 1 1 3 3 3 0 Spindle pole body component Spc42p Baculo_PEP_C PF04513.7 CEH18825.1 - 0.86 9.4 5.2 0.55 10.0 0.6 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 CEH18825.1 - 1.8 6.8 21.2 0.091 11.2 2.1 2.1 2 0 0 2 2 2 0 AAA domain Bacillus_HBL PF05791.6 CEH18825.1 - 9.4 5.5 9.5 1.4 8.2 2.7 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TPR_2 PF07719.12 CEH18826.1 - 0.00012 21.7 1.7 8.5 6.5 0.7 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEH18826.1 - 0.00029 21.3 18.8 0.0021 18.7 0.0 4.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CEH18826.1 - 0.0013 18.3 0.7 0.38 10.4 0.3 2.7 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.1 CEH18826.1 - 0.0021 17.8 2.5 0.05 13.4 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEH18826.1 - 0.0075 16.8 16.7 0.4 11.4 0.1 5.1 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEH18826.1 - 0.012 15.3 0.2 22 5.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CEH18826.1 - 0.02 15.2 0.3 0.02 15.2 0.2 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CEH18826.1 - 0.021 14.7 2.7 5.3 7.0 0.0 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEH18826.1 - 0.025 14.3 1.7 0.48 10.3 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CEH18826.1 - 0.056 13.9 2.0 8.4 7.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 CEH18826.1 - 0.22 10.5 6.0 0.12 11.4 2.4 1.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Metallophos PF00149.23 CEH18827.1 - 1.1e-43 148.9 0.1 1.4e-43 148.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Transaldolase PF00923.14 CEH18828.1 - 6.7e-94 314.2 0.5 7.6e-94 314.0 0.3 1.0 1 0 0 1 1 1 1 Transaldolase EI24 PF07264.6 CEH18829.1 - 0.056 12.8 9.1 0.18 11.2 6.3 2.0 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Ribonucleas_3_3 PF14622.1 CEH18830.1 - 3.4e-24 85.2 0.1 5.8e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like zf-C2H2 PF00096.21 CEH18831.1 - 5.8e-10 38.9 14.1 1.8e-05 24.8 2.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH18831.1 - 5.5e-06 26.3 11.7 0.0071 16.6 1.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEH18831.1 - 2.5e-05 24.3 3.6 2.5e-05 24.3 2.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain Auxin_repressed PF05564.7 CEH18831.1 - 1.1 9.8 8.8 0.31 11.6 0.4 3.3 3 0 0 3 3 3 0 Dormancy/auxin associated protein Mo25 PF08569.6 CEH18833.1 - 3.1e-127 424.2 5.2 3.8e-127 423.9 3.6 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 CEH18833.1 - 0.046 13.9 0.0 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats DUF4479 PF14794.1 CEH18833.1 - 0.2 11.2 3.2 2.7 7.5 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4479) RepA_N PF06970.6 CEH18833.1 - 3.2 7.6 6.4 0.24 11.1 0.6 2.1 3 0 0 3 3 3 0 Replication initiator protein A (RepA) N-terminus CH PF00307.26 CEH18834.1 - 3.9e-67 223.0 0.0 2.6e-18 66.0 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CEH18834.1 - 2.4e-07 30.2 0.0 0.4 10.3 0.0 3.5 3 0 0 3 3 3 3 CAMSAP CH domain EF-hand_7 PF13499.1 CEH18834.1 - 1.8e-06 27.9 0.2 4.3e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CEH18834.1 - 0.00016 20.7 0.6 0.014 14.6 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CEH18834.1 - 0.0014 18.3 0.5 25 5.0 0.0 3.9 3 0 0 3 3 3 1 EF-hand domain Sec2p PF06428.6 CEH18835.1 - 4.2e-14 52.2 5.2 4.2e-14 52.2 3.6 2.9 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p HALZ PF02183.13 CEH18835.1 - 4.7 6.9 6.0 11 5.8 0.0 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper AMP-binding PF00501.23 CEH18836.1 - 6.5e-94 314.6 0.1 8.1e-94 314.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEH18836.1 - 9.5e-25 87.3 0.3 4.6e-22 78.7 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain DUF1967 PF09269.6 CEH18836.1 - 0.07 12.8 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) DEAD PF00270.24 CEH18837.1 - 3.3e-41 140.6 0.4 1.4e-40 138.5 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH18837.1 - 5.3e-29 99.8 0.2 1.4e-28 98.5 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CEH18837.1 - 0.005 15.2 0.0 0.043 12.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) AAA_19 PF13245.1 CEH18837.1 - 0.0055 16.4 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain SecA_DEAD PF07517.9 CEH18837.1 - 0.022 14.0 0.0 0.056 12.7 0.0 1.6 1 0 0 1 1 1 0 SecA DEAD-like domain ResIII PF04851.10 CEH18837.1 - 0.026 14.3 0.0 0.068 13.0 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.20 CEH18837.1 - 0.097 11.7 0.1 0.47 9.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Ribul_P_3_epim PF00834.14 CEH18838.1 - 8.9e-67 224.0 0.1 1.1e-66 223.8 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 CEH18838.1 - 0.0016 18.0 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.19 CEH18838.1 - 0.031 13.6 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.12 CEH18838.1 - 0.063 12.5 0.2 0.14 11.3 0.1 1.8 1 1 0 1 1 1 0 PcrB family PG_binding_3 PF09374.5 CEH18838.1 - 0.098 12.6 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain LSM PF01423.17 CEH18839.1 - 1.5e-16 59.6 0.6 1.9e-16 59.3 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CEH18839.1 - 0.0091 15.9 0.1 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain BPL_C PF02237.12 CEH18839.1 - 0.037 13.7 0.2 0.071 12.8 0.1 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Gemin7 PF11095.3 CEH18839.1 - 0.052 13.2 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DUF3247 PF11607.3 CEH18839.1 - 0.068 13.4 0.0 0.074 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) WD40 PF00400.27 CEH18840.1 - 1.1e-53 177.2 29.1 1.6e-08 34.0 0.1 12.2 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 CEH18840.1 - 2.9e-16 59.3 0.3 5.4e-16 58.4 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CEH18840.1 - 1.6e-05 23.3 0.3 0.059 11.4 0.0 3.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 CEH18840.1 - 3.3e-05 23.6 0.9 0.79 9.4 0.0 5.0 5 1 0 5 5 5 1 Transcription factor IIIC subunit delta N-term eIF2A PF08662.6 CEH18840.1 - 0.00012 21.8 0.2 29 4.2 0.0 5.7 4 2 2 7 7 7 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CEH18840.1 - 0.014 13.6 0.0 1.3 7.2 0.0 3.1 3 0 0 3 3 3 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 CEH18840.1 - 0.04 12.6 0.1 0.67 8.6 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like PD40 PF07676.7 CEH18840.1 - 0.053 13.2 0.0 14 5.5 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PI3_PI4_kinase PF00454.22 CEH18841.1 - 3.2e-29 102.0 0.0 5.4e-28 98.0 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CEH18841.1 - 2.1e-20 72.6 0.0 4.7e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Hemerythrin PF01814.18 CEH18842.1 - 9.5e-10 38.7 1.9 1.1e-09 38.5 1.3 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PEP-utilisers_N PF05524.8 CEH18842.1 - 0.086 12.6 0.2 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Tenui_NCP PF04876.7 CEH18842.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein JAB PF01398.16 CEH18843.1 - 3.8e-16 58.8 0.0 8.6e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 CEH18843.1 - 2.3e-06 27.5 0.0 5.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 CEH18843.1 - 3.7e-05 23.2 0.0 0.00012 21.5 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DEAD PF00270.24 CEH18846.1 - 9.3e-42 142.3 0.0 1.7e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH18846.1 - 5.2e-22 77.4 0.0 1.1e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CEH18846.1 - 2.3e-20 71.9 0.1 5.6e-20 70.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) SHQ1 PF04925.10 CEH18850.1 - 2.3e-25 89.1 0.0 3.6e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein Ammonium_transp PF00909.16 CEH18851.1 - 4.9e-86 288.6 27.1 6.3e-86 288.3 18.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SCAMP PF04144.8 CEH18851.1 - 0.18 11.6 6.1 4.5 7.1 0.4 2.8 2 1 0 2 2 2 0 SCAMP family MBOAT_2 PF13813.1 CEH18852.1 - 2.4e-08 33.9 0.5 7.4e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family RIB43A PF05914.7 CEH18852.1 - 1.4 7.4 6.8 0.046 12.3 0.6 1.4 2 0 0 2 2 2 0 RIB43A WAC_Acf1_DNA_bd PF10537.4 CEH18856.1 - 3.3e-33 113.8 0.2 9.3e-33 112.4 0.1 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CEH18856.1 - 5.4e-11 42.1 0.0 1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 CEH18856.1 - 2.2e-05 24.1 0.2 7.7e-05 22.4 0.1 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 CEH18856.1 - 0.017 15.0 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 CEH18856.1 - 0.023 14.4 0.9 0.06 13.1 0.0 2.2 3 0 0 3 3 3 0 WSTF, HB1, Itc1p, MBD9 motif 3 Choline_kinase PF01633.15 CEH18857.1 - 4.2e-13 49.3 0.0 1e-12 48.0 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CEH18857.1 - 3.5e-06 26.9 5.5 0.043 13.5 0.0 2.9 2 1 0 2 2 2 2 Phosphotransferase enzyme family tRNA_deacylase PF04414.7 CEH18857.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase RRM_1 PF00076.17 CEH18858.1 - 3.4e-08 32.9 0.1 0.0012 18.4 0.0 3.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH18858.1 - 0.0014 18.4 0.0 0.31 10.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH18858.1 - 0.0057 16.6 0.0 0.73 9.8 0.0 3.4 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2665 PF11654.3 CEH18859.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) UPRTase PF14681.1 CEH18860.1 - 6.3e-65 218.2 0.0 7.3e-65 218.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CEH18860.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Aconitase PF00330.15 CEH18861.1 - 2.5e-72 243.8 1.3 4.4e-48 163.9 0.1 2.9 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CEH18861.1 - 4.3e-20 72.1 0.0 1.5e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 Aconitase C-terminal domain adh_short PF00106.20 CEH18863.1 - 4.1e-12 46.3 6.2 2.5e-10 40.5 4.3 2.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH18863.1 - 6e-08 32.7 0.4 1.1e-05 25.3 0.3 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH18863.1 - 3.3e-07 30.1 0.5 7e-07 29.0 0.3 1.5 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 CEH18863.1 - 0.0085 15.7 0.3 0.014 15.0 0.2 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Suf PF05843.9 CEH18866.1 - 2.6e-73 247.2 0.0 9.6e-72 242.0 0.0 3.4 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_16 PF13432.1 CEH18866.1 - 0.0003 21.3 0.1 0.0003 21.3 0.1 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 CEH18866.1 - 0.0004 20.6 2.7 0.12 12.7 0.0 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEH18866.1 - 0.0019 18.6 21.6 0.01 16.3 0.4 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 CEH18866.1 - 0.1 13.0 3.2 1 9.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SMC_N PF02463.14 CEH18867.1 - 2.6e-25 88.9 0.0 1.1e-24 86.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CEH18867.1 - 2.3e-15 57.4 17.5 2.3e-15 57.4 12.2 5.2 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 CEH18867.1 - 1.8e-05 24.8 1.2 0.018 15.0 0.7 2.6 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CEH18867.1 - 0.00016 20.8 2.6 0.00016 20.8 1.8 2.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 CEH18867.1 - 0.00023 20.6 0.1 0.00048 19.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 CEH18867.1 - 0.0049 16.7 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF3584 PF12128.3 CEH18867.1 - 0.016 12.5 77.1 0.051 10.9 26.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 CEH18867.1 - 2.7 7.1 18.8 0.64 9.1 0.4 3.8 3 1 2 5 5 5 0 Reovirus sigma C capsid protein HEAT_2 PF13646.1 CEH18868.1 - 2.4e-06 27.7 14.7 0.0024 18.1 0.0 6.7 6 1 0 6 6 6 2 HEAT repeats HEAT PF02985.17 CEH18868.1 - 9.5e-05 22.1 4.6 0.55 10.4 0.0 5.8 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.2 CEH18868.1 - 0.088 13.2 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region IF4E PF01652.13 CEH18869.1 - 3.2e-48 163.3 0.2 5.1e-37 126.9 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic initiation factor 4E Thioredoxin PF00085.15 CEH18870.1 - 0.017 14.7 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin SNF2_N PF00176.18 CEH18871.1 - 1.7e-38 132.1 0.0 3.8e-38 130.9 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CEH18871.1 - 3e-05 23.8 0.1 6.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 CEH18871.1 - 0.0001 21.8 4.3 0.00023 20.7 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CEH18871.1 - 0.00024 20.7 6.0 0.00061 19.4 4.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CEH18871.1 - 0.011 15.7 9.1 0.027 14.4 6.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LAGLIDADG_WhiA PF14527.1 CEH18871.1 - 0.047 13.5 0.3 0.16 11.8 0.2 1.9 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain DUF3776 PF12618.3 CEH18871.1 - 0.048 14.2 1.3 13 6.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3776) zf-RING_2 PF13639.1 CEH18871.1 - 0.18 11.6 13.3 0.0084 15.9 4.8 2.1 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 CEH18871.1 - 1.1 9.0 13.5 0.032 13.8 4.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 CEH18872.1 - 3.5e-48 164.0 0.0 4.6e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH18872.1 - 7.3e-35 120.2 0.0 8.2e-34 116.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH18872.1 - 0.0068 15.3 0.0 0.05 12.5 0.0 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CEH18872.1 - 0.0087 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Transketolase_N PF00456.16 CEH18873.1 - 1.5e-140 467.7 0.1 2.1e-140 467.3 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CEH18873.1 - 1.6e-42 145.0 0.0 3.7e-42 143.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CEH18873.1 - 1.1e-09 38.2 0.0 2.4e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CEH18873.1 - 4.1e-05 22.6 0.4 0.00017 20.6 0.3 2.0 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 CEH18873.1 - 0.00027 19.7 0.0 0.00047 18.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component NAC PF01849.13 CEH18874.1 - 4.4e-20 70.9 0.0 9.6e-20 69.8 0.0 1.6 1 0 0 1 1 1 1 NAC domain SET PF00856.23 CEH18875.1 - 2.4e-25 89.7 3.9 3.2e-25 89.3 0.0 2.8 2 1 0 2 2 2 1 SET domain N-SET PF11764.3 CEH18875.1 - 1.6e-14 54.1 7.5 1.1e-13 51.4 0.6 3.9 2 1 1 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.17 CEH18875.1 - 1e-05 25.0 0.0 5.4e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH18875.1 - 0.036 14.0 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pmp3 PF01679.12 CEH18877.1 - 5.4e-20 70.8 18.4 1.4e-16 59.8 5.3 2.1 2 0 0 2 2 2 2 Proteolipid membrane potential modulator Mg_trans_NIPA PF05653.9 CEH18878.1 - 8.2e-103 343.4 10.3 1.1e-102 343.1 7.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CEH18878.1 - 5.5e-07 29.7 0.5 5.5e-07 29.7 0.4 3.7 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 CEH18878.1 - 0.00052 20.0 26.9 0.0053 16.8 4.4 3.1 3 1 0 3 3 3 2 EamA-like transporter family Mif2_N PF15624.1 CEH18878.1 - 0.098 13.2 1.4 0.27 11.8 1.0 1.7 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF202 PF02656.10 CEH18878.1 - 3 8.1 0.0 3 8.1 0.0 4.7 3 2 0 3 3 3 0 Domain of unknown function (DUF202) UCH PF00443.24 CEH18879.1 - 4.8e-09 35.7 0.0 5.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEH18879.1 - 0.005 16.3 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4188 PF13826.1 CEH18881.1 - 8.9e-18 64.4 0.1 1.1e-17 64.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) PCEMA1 PF07418.6 CEH18882.1 - 0.21 10.9 3.0 0.26 10.6 2.1 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF572 PF04502.8 CEH18882.1 - 4.8 6.3 11.3 6.5 5.8 7.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) HECT_2 PF09814.4 CEH18883.1 - 5.5e-25 87.8 0.0 1.1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Rubredoxin PF00301.15 CEH18883.1 - 0.0083 15.9 0.4 0.031 14.1 0.1 2.1 2 0 0 2 2 2 1 Rubredoxin DUF812 PF05667.6 CEH18883.1 - 0.014 13.9 0.3 0.036 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GoLoco PF02188.12 CEH18883.1 - 1.8 7.9 8.3 0.073 12.4 0.4 2.7 3 0 0 3 3 3 0 GoLoco motif YTH PF04146.10 CEH18888.1 - 5e-38 129.8 0.0 8.4e-38 129.1 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Beta_elim_lyase PF01212.16 CEH18889.1 - 8.1e-49 166.3 0.9 2e-39 135.4 0.0 2.2 2 0 0 2 2 2 2 Beta-eliminating lyase Svf1 PF08622.5 CEH18890.1 - 1.2e-87 293.9 0.0 2.4e-87 292.9 0.0 1.4 1 1 0 1 1 1 1 Svf1-like DUF346 PF03984.8 CEH18890.1 - 0.043 13.2 0.5 0.22 11.0 0.0 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) MS_channel PF00924.13 CEH18891.1 - 2.8e-18 65.9 0.5 5e-18 65.1 0.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel ChAPs PF09295.5 CEH18893.1 - 1.9e-157 524.0 0.0 2.8e-157 523.5 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 CEH18893.1 - 2.3e-11 43.8 1.1 1.9e-06 28.0 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CEH18893.1 - 2.6e-10 39.7 1.3 6.2e-05 22.5 0.0 3.8 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CEH18893.1 - 3.1e-07 29.8 3.8 0.14 12.1 0.0 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CEH18893.1 - 3.4e-06 27.0 1.7 0.12 12.5 0.1 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CEH18893.1 - 5.1e-06 26.5 0.5 6.2 7.5 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CEH18893.1 - 0.00021 21.6 12.4 1.5 9.6 0.2 6.9 4 2 4 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 CEH18893.1 - 0.00054 19.5 0.2 1.4 8.9 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CEH18893.1 - 0.0088 16.6 13.4 0.16 12.6 0.3 4.4 3 1 2 5 5 5 2 Tetratricopeptide repeat NDK PF00334.14 CEH18894.1 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Sporozoite_P67 PF05642.6 CEH18898.1 - 0.93 7.2 3.5 1.3 6.7 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF747 PF05346.6 CEH18899.1 - 3.1e-120 401.2 0.1 3.9e-120 400.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Cellulase PF00150.13 CEH18901.1 - 4.5e-15 55.5 0.0 6.9e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mss4 PF04421.8 CEH18902.1 - 3.8e-08 33.0 0.2 8.9e-05 22.2 0.2 2.5 2 0 0 2 2 2 2 Mss4 protein Acetyltransf_1 PF00583.19 CEH18902.1 - 8.7e-07 28.8 0.0 3.4e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CEH18902.1 - 1.4e-05 25.1 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CEH18902.1 - 0.0023 17.6 0.0 0.0077 15.9 0.0 1.9 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CEH18902.1 - 0.013 15.6 0.0 0.067 13.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CEH18902.1 - 0.044 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PLA2_B PF01735.13 CEH18904.1 - 3.2e-127 424.6 1.0 4.2e-127 424.3 0.7 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PARP PF00644.15 CEH18905.1 - 5.5e-56 189.2 0.3 1.1e-55 188.3 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 CEH18905.1 - 4.7e-31 107.2 0.0 7.8e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 CEH18905.1 - 7.8e-19 67.4 0.0 1.8e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 CEH18905.1 - 1.3e-09 38.0 0.0 2.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CEH18905.1 - 1.3e-08 34.5 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain DUF3246 PF11596.3 CEH18905.1 - 0.019 14.2 0.9 0.034 13.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CDC45 PF02724.9 CEH18905.1 - 6.4 4.6 7.9 11 3.8 5.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4013 PF13197.1 CEH18906.1 - 5.3 6.3 11.5 0.073 12.3 1.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4013) Sporozoite_P67 PF05642.6 CEH18907.1 - 0.028 12.3 6.3 0.03 12.1 4.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BSP_II PF05432.6 CEH18907.1 - 0.04 13.2 0.8 0.045 13.0 0.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PH PF00169.24 CEH18908.1 - 6.8e-39 132.2 1.6 2.2e-18 66.3 2.3 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 CEH18908.1 - 2.2e-18 66.5 14.1 3.9e-07 30.3 5.9 4.2 3 1 0 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.1 CEH18908.1 - 4.6e-18 65.0 4.7 7.8e-07 28.9 1.9 3.2 3 0 0 3 3 3 3 PH domain PH_8 PF15409.1 CEH18908.1 - 1.4e-12 47.4 4.3 1.5e-07 31.3 2.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_4 PF15404.1 CEH18908.1 - 1.4e-05 24.6 3.4 0.093 12.2 0.2 3.6 2 1 1 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 CEH18908.1 - 5.5e-05 23.2 4.8 0.0036 17.4 1.1 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain Mcp5_PH PF12814.2 CEH18908.1 - 6.7e-05 22.8 8.4 0.022 14.6 0.0 3.0 3 0 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology PH_7 PF15408.1 CEH18908.1 - 0.00044 20.0 0.5 0.0035 17.1 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Sec3-PIP2_bind PF15277.1 CEH18908.1 - 0.039 13.8 1.3 0.073 12.9 0.9 1.5 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps36_ESCRT-II PF11605.3 CEH18908.1 - 0.13 12.1 2.8 1.1 9.1 0.1 2.7 2 1 1 3 3 3 0 Vacuolar protein sorting protein 36 Vps36 NAP PF00956.13 CEH18909.1 - 1.8e-33 115.7 21.3 7.1e-33 113.7 14.8 1.8 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Nucleoplasmin PF03066.10 CEH18909.1 - 0.0018 17.7 6.6 0.0039 16.7 4.6 1.6 1 0 0 1 1 1 1 Nucleoplasmin OmpH PF03938.9 CEH18909.1 - 0.28 11.0 2.5 0.72 9.7 0.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Nro1 PF12753.2 CEH18909.1 - 0.51 9.2 9.3 1.1 8.1 6.5 1.5 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 NOA36 PF06524.7 CEH18909.1 - 1.7 7.8 7.9 2.8 7.1 5.5 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 CEH18909.1 - 2 8.6 19.3 4.5 7.5 13.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 CEH18909.1 - 5.1 7.3 11.5 13 6.0 8.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Spc7 PF08317.6 CEH18910.1 - 2.3e-28 98.8 0.7 2.3e-28 98.8 0.5 2.3 2 0 0 2 2 2 2 Spc7 kinetochore protein Lzipper-MIP1 PF14389.1 CEH18910.1 - 0.0021 18.1 3.1 0.0021 18.1 2.2 2.7 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 DivIVA PF05103.8 CEH18910.1 - 0.0094 16.0 3.6 0.0094 16.0 2.5 4.9 4 1 2 6 6 6 1 DivIVA protein IlvN PF07991.7 CEH18911.1 - 6.6e-42 142.6 0.0 1.2e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 CEH18911.1 - 1.2e-40 138.8 0.0 1.7e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Methyltransf_7 PF03492.10 CEH18913.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Cofilin_ADF PF00241.15 CEH18915.1 - 7.9e-06 25.7 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Arrestin_N PF00339.24 CEH18915.1 - 0.31 10.8 0.0 0.71 9.6 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Cwf_Cwc_15 PF04889.7 CEH18915.1 - 3.9 7.1 8.3 10 5.7 5.8 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PS_Dcarbxylase PF02666.10 CEH18916.1 - 5e-74 247.9 0.0 7.2e-72 240.9 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DMRL_synthase PF00885.14 CEH18918.1 - 1.7e-43 147.7 0.1 5.6e-26 90.9 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase ADAM_spacer1 PF05986.9 CEH18918.1 - 0.0093 15.8 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 zf-H2C2_2 PF13465.1 CEH18919.1 - 1e-08 35.0 0.1 2.4e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.21 CEH18919.1 - 4.8e-07 29.7 2.1 1.1e-05 25.4 0.3 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH18919.1 - 0.00063 19.8 1.8 0.0061 16.8 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger RRF_GI PF12614.3 CEH18919.1 - 0.02 14.6 4.4 0.79 9.5 0.3 2.2 1 1 1 2 2 2 0 Ribosome recycling factor zf-met PF12874.2 CEH18919.1 - 0.045 13.9 1.1 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2229 PF09989.4 CEH18919.1 - 0.053 12.9 1.7 0.53 9.7 0.1 2.1 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) HAP1_N PF04849.8 CEH18919.1 - 0.11 11.4 6.0 0.63 8.9 0.5 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region PhaP_Bmeg PF09602.5 CEH18919.1 - 0.11 12.2 0.8 2.7 7.7 0.6 2.1 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ApoLp-III PF07464.6 CEH18919.1 - 0.14 12.1 1.6 5 7.1 0.1 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) zf-C2H2_jaz PF12171.3 CEH18919.1 - 0.16 12.1 1.2 0.49 10.5 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CEH18919.1 - 0.17 11.8 0.4 4 7.4 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DUF904 PF06005.7 CEH18919.1 - 4.9 7.5 7.8 15 5.9 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Saccharop_dh PF03435.13 CEH18920.1 - 2.4e-05 23.5 0.0 0.00032 19.8 0.0 2.0 2 0 0 2 2 2 2 Saccharopine dehydrogenase Asparaginase_2 PF01112.13 CEH18921.1 - 2.8e-34 118.2 0.1 1e-18 67.1 0.0 2.9 3 0 0 3 3 3 3 Asparaginase rve PF00665.21 CEH18927.1 - 1.6e-21 76.6 0.0 4.1e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CEH18927.1 - 2.3e-20 72.8 0.1 4e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CEH18927.1 - 0.007 15.8 0.9 0.066 12.7 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain PHP PF02811.14 CEH18927.1 - 0.0076 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 PHP domain Adhes-Ig_like PF09085.5 CEH18938.1 - 0.037 13.8 0.1 0.051 13.4 0.0 1.5 1 1 0 1 1 1 0 Adhesion molecule, immunoglobulin-like NGP1NT PF08153.7 CEH18940.1 - 6.1e-42 142.6 1.4 1.7e-41 141.1 0.0 2.4 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CEH18940.1 - 2.1e-18 66.3 1.9 3.6e-15 55.9 0.0 2.7 3 0 0 3 3 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CEH18940.1 - 4.1e-06 26.1 0.5 8.1e-06 25.2 0.1 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 CEH18940.1 - 8.6e-06 25.1 0.1 0.026 13.7 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 CEH18940.1 - 4.9e-05 22.8 0.3 0.018 14.4 0.1 3.6 2 1 0 4 4 4 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CEH18940.1 - 0.00065 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 CEH18940.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Coatomer_E PF04733.9 CEH18940.1 - 0.025 13.8 0.0 0.061 12.5 0.0 1.6 2 0 0 2 2 2 0 Coatomer epsilon subunit Dynamin_N PF00350.18 CEH18940.1 - 0.55 10.0 6.6 2.3 7.9 0.0 3.7 3 1 1 4 4 4 0 Dynamin family Nop14 PF04147.7 CEH18940.1 - 2.4 5.9 18.1 3.4 5.4 12.5 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CEH18940.1 - 4.1 5.7 16.8 6.3 5.1 11.6 1.2 1 0 0 1 1 1 0 Daxx Family Prothymosin PF03247.9 CEH18940.1 - 8.2 6.6 28.3 0.29 11.2 15.2 1.9 2 0 0 2 2 1 0 Prothymosin/parathymosin family Thg1C PF14413.1 CEH18941.1 - 1.3e-44 150.7 0.1 2.3e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 CEH18941.1 - 2.7e-35 120.9 0.1 9.3e-35 119.1 0.1 1.8 1 1 0 1 1 1 1 tRNAHis guanylyltransferase TRAPPC10 PF12584.3 CEH18942.1 - 3.1e-22 78.6 0.0 6.8e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 EHN PF06441.7 CEH18943.1 - 1.9e-21 76.0 0.0 4.1e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 CEH18943.1 - 0.088 12.3 0.3 0.31 10.5 0.1 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold SET PF00856.23 CEH18944.1 - 2.6e-21 76.6 0.0 4e-20 72.7 0.0 2.5 2 1 0 2 2 2 1 SET domain RRM_1 PF00076.17 CEH18945.1 - 6.4e-13 48.1 0.0 8.3e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH18945.1 - 7e-12 45.1 0.0 9.2e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH18945.1 - 5.6e-10 38.9 0.0 7.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CEH18945.1 - 0.046 13.5 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 CEH18945.1 - 0.069 12.8 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Arginase PF00491.16 CEH18947.1 - 5.1e-80 268.7 0.0 6e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family HMGL-like PF00682.14 CEH18948.1 - 7.5e-72 241.8 1.1 1.2e-71 241.1 0.8 1.3 1 0 0 1 1 1 1 HMGL-like DnaJ PF00226.26 CEH18950.1 - 6.3e-20 70.6 0.5 1.2e-19 69.7 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 CEH18950.1 - 1.4e-11 44.5 0.0 2.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DEAD PF00270.24 CEH18951.1 - 5.9e-40 136.5 0.0 2.1e-39 134.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH18951.1 - 8.1e-22 76.8 0.0 1.6e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CEH18951.1 - 7.7e-18 64.0 0.9 1.9e-17 62.8 0.7 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 CEH18951.1 - 0.077 12.8 0.0 0.31 10.8 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TP6A_N PF04406.9 CEH18952.1 - 0.0087 15.7 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF4309 PF14172.1 CEH18964.1 - 0.064 13.2 0.1 0.075 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) Dehalogenase PF13486.1 CEH18964.1 - 0.1 12.0 0.2 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Reductive dehalogenase subunit ERM PF00769.14 CEH18965.1 - 0.0016 17.9 9.1 0.0018 17.8 6.1 1.3 1 1 0 1 1 1 1 Ezrin/radixin/moesin family DUF2346 PF09803.4 CEH18965.1 - 0.024 14.5 0.2 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) DUF3138 PF11336.3 CEH18965.1 - 0.39 8.8 3.8 0.49 8.5 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Dsh_C PF12316.3 CEH18971.1 - 0.02 15.0 0.6 0.02 15.0 0.4 1.9 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal BUD22 PF09073.5 CEH18971.1 - 0.24 10.4 18.0 0.34 9.9 12.5 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 CEH18971.1 - 0.34 8.7 20.7 0.42 8.4 14.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CEH18971.1 - 0.5 8.7 23.4 0.044 12.2 12.8 1.5 2 0 0 2 2 2 0 Daxx Family TFIIF_alpha PF05793.7 CEH18971.1 - 0.94 7.7 18.2 1.2 7.3 12.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 CEH18971.1 - 1.6 8.0 15.0 2.5 7.3 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Rota_NSP3 PF01665.11 CEH18973.1 - 0.0018 17.2 0.7 0.013 14.4 0.1 2.0 1 1 1 2 2 2 1 Rotavirus non-structural protein NSP3 Tup_N PF08581.5 CEH18973.1 - 0.009 16.1 2.0 0.043 14.0 0.0 2.5 3 0 0 3 3 2 1 Tup N-terminal DUF342 PF03961.8 CEH18973.1 - 0.011 14.2 2.4 0.014 13.8 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pkip-1 PF06878.6 CEH18973.1 - 0.011 15.5 1.2 0.57 10.0 0.7 2.2 1 1 0 1 1 1 0 Pkip-1 protein HALZ PF02183.13 CEH18973.1 - 0.016 14.8 0.4 0.016 14.8 0.3 2.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 CEH18973.1 - 0.019 14.1 0.2 0.023 13.9 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Filament PF00038.16 CEH18973.1 - 0.021 14.3 4.5 0.37 10.2 1.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein TMF_DNA_bd PF12329.3 CEH18973.1 - 0.066 13.0 3.5 0.57 10.0 0.7 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MRP-L28 PF09812.4 CEH18973.1 - 0.09 12.5 2.9 0.16 11.8 2.0 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 Methyltransf_14 PF08484.6 CEH18973.1 - 0.092 12.2 1.3 1.9 8.0 0.4 2.2 1 1 1 2 2 2 0 C-methyltransferase C-terminal domain Phage_GP20 PF06810.6 CEH18973.1 - 0.15 11.5 7.4 0.27 10.6 1.2 2.5 1 1 2 3 3 3 0 Phage minor structural protein GP20 ATG16 PF08614.6 CEH18973.1 - 0.26 11.0 5.5 0.25 11.1 2.9 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Bap31 PF05529.7 CEH18973.1 - 0.34 10.3 3.7 0.2 11.1 0.8 1.8 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Rootletin PF15035.1 CEH18973.1 - 0.38 10.7 4.5 0.066 13.1 0.5 1.7 2 0 0 2 2 1 0 Ciliary rootlet component, centrosome cohesion Ax_dynein_light PF10211.4 CEH18973.1 - 0.43 10.3 5.6 0.061 13.1 0.9 1.8 2 1 0 2 2 1 0 Axonemal dynein light chain HAUS6_N PF14661.1 CEH18973.1 - 0.49 9.7 7.2 0.13 11.5 3.1 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Z1 PF10593.4 CEH18973.1 - 0.77 8.9 3.2 0.57 9.3 1.0 1.6 1 1 1 2 2 2 0 Z1 domain Seryl_tRNA_N PF02403.17 CEH18973.1 - 0.79 9.7 6.7 0.42 10.6 1.8 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 CEH18973.1 - 1 9.1 11.1 4.4 7.0 7.7 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Viral_P18 PF04521.8 CEH18973.1 - 1.3 8.5 3.7 1 8.8 0.6 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TMF_TATA_bd PF12325.3 CEH18973.1 - 1.5 8.5 5.4 0.51 10.0 1.4 2.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Myc_N PF01056.13 CEH18974.1 - 0.23 10.5 3.5 0.31 10.1 2.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region StbA PF06406.6 CEH18975.1 - 0.0032 16.4 0.5 0.0054 15.7 0.3 1.3 1 0 0 1 1 1 1 StbA protein Herpes_BLRF2 PF05812.7 CEH18975.1 - 0.0036 17.0 0.5 0.011 15.5 0.4 1.9 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein Exonuc_VII_L PF02601.10 CEH18975.1 - 0.01 15.0 4.5 0.014 14.5 3.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DinB_2 PF12867.2 CEH18975.1 - 0.016 15.5 0.2 0.03 14.6 0.1 1.5 1 0 0 1 1 1 0 DinB superfamily DUF1640 PF07798.6 CEH18975.1 - 0.7 9.9 7.6 5.6 6.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF3526 PF12040.3 CEH18975.1 - 1.8 8.7 7.5 1.2 9.2 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3526) PAP_central PF04928.12 CEH18975.1 - 5.2 5.7 7.3 6.5 5.4 4.8 1.5 1 1 0 1 1 1 0 Poly(A) polymerase central domain UPF0242 PF06785.6 CEH18975.1 - 5.5 5.5 7.3 0.24 10.0 1.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) IncA PF04156.9 CEH18975.1 - 6.9 6.2 12.0 1.8 8.1 1.0 2.4 2 0 0 2 2 2 0 IncA protein Evr1_Alr PF04777.8 CEH18977.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Erv1 / Alr family tRNA-synt_His PF13393.1 CEH18990.1 - 0.0049 15.9 0.9 0.0066 15.5 0.6 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase IncA PF04156.9 CEH18990.1 - 0.03 13.9 0.4 0.041 13.4 0.3 1.2 1 0 0 1 1 1 0 IncA protein Uds1 PF15456.1 CEH18990.1 - 0.089 12.7 1.0 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 Up-regulated During Septation FlaC_arch PF05377.6 CEH18990.1 - 0.21 11.5 0.6 1.8 8.5 0.4 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) RP-C_C PF11800.3 CEH18993.1 - 0.029 14.0 0.2 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region G-gamma PF00631.17 CEH18996.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 GGL domain Chorion_2 PF03964.10 CEH19001.1 - 0.13 12.7 5.7 1.1 9.8 1.2 2.2 2 0 0 2 2 2 0 Chorion family 2 SF-assemblin PF06705.6 CEH19002.1 - 0.025 13.7 0.7 0.036 13.2 0.5 1.3 1 1 0 1 1 1 0 SF-assemblin/beta giardin FGGY_N PF00370.16 CEH19002.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain DUF883 PF05957.8 CEH19002.1 - 0.33 11.3 7.3 0.36 11.2 0.8 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Sporozoite_P67 PF05642.6 CEH19005.1 - 0.13 10.0 0.1 0.15 9.8 0.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Endonuc_Holl PF10107.4 CEH19009.1 - 0.089 12.4 0.2 5.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase FliC_SP PF12613.3 CEH19009.1 - 0.95 9.7 5.6 12 6.1 0.2 2.4 2 0 0 2 2 2 0 Flagellin structural protein MFS_1 PF07690.11 CEH19010.1 - 4.4e-19 68.4 42.3 4.4e-19 68.4 29.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1256 PF06866.6 CEH19010.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) AMP-binding PF00501.23 CEH19011.1 - 2.1e-36 125.2 0.0 2.4e-35 121.7 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CEH19011.1 - 8.5e-11 41.2 0.0 1.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein EF-hand_7 PF13499.1 CEH19012.1 - 1.1e-13 51.0 0.0 5.3e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CEH19012.1 - 3.1e-13 48.4 1.7 3.5e-05 23.3 0.1 3.6 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CEH19012.1 - 3.6e-11 41.5 0.7 0.00025 20.1 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 CEH19012.1 - 3.9e-07 29.5 0.2 0.0003 20.3 0.0 3.7 2 2 2 4 4 4 1 EF-hand domain pair EF-hand_9 PF14658.1 CEH19012.1 - 3.3e-06 26.9 0.0 0.00074 19.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CEH19012.1 - 0.0012 18.1 0.1 1.3 8.4 0.0 2.7 2 0 0 2 2 2 2 EF hand Big_3_2 PF12245.3 CEH19012.1 - 0.11 12.0 0.1 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) UPF0154 PF03672.8 CEH19012.1 - 0.11 12.0 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Pik1 PF11522.3 CEH19015.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 zf-FPG_IleRS PF06827.9 CEH19018.1 - 0.004 16.7 2.4 1.2 8.8 0.1 2.5 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS zf-LITAF-like PF10601.4 CEH19018.1 - 0.18 11.7 5.8 1.4 8.8 0.7 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CEH19018.1 - 0.21 11.3 5.2 0.5 10.2 3.6 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Rubredoxin PF00301.15 CEH19018.1 - 0.45 10.4 3.2 3.2 7.6 0.3 2.5 2 0 0 2 2 2 0 Rubredoxin DNA_ligase_A_M PF01068.16 CEH19019.1 - 4e-51 173.2 0.1 9.7e-40 136.0 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CEH19019.1 - 2.7e-50 170.6 0.0 4.2e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CEH19019.1 - 3.8e-24 84.8 0.0 9.8e-24 83.5 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region eIF-3c_N PF05470.7 CEH19019.1 - 1.6e-06 26.5 0.0 6.4e-05 21.2 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_ligase_OB_2 PF14743.1 CEH19019.1 - 0.009 15.6 0.4 1 9.0 0.0 2.7 3 0 0 3 3 3 1 DNA ligase OB-like domain Nop14 PF04147.7 CEH19019.1 - 0.22 9.4 26.8 0.33 8.8 18.6 1.2 1 0 0 1 1 1 0 Nop14-like family SHS2_Rpb7-N PF03876.12 CEH19020.1 - 2.5e-12 46.7 0.0 3.8e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CEH19020.1 - 5.1e-09 36.1 0.3 1.2e-08 34.9 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain SNARE PF05739.14 CEH19021.1 - 5.9e-06 25.8 0.1 7.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 CEH19021.1 - 0.0057 16.1 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 UPF0233 PF06781.7 CEH19021.1 - 0.021 14.4 2.5 0.034 13.7 1.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF4234 PF14018.1 CEH19021.1 - 0.062 13.0 2.6 0.068 12.9 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Spc7_N PF15402.1 CEH19025.1 - 1.3 6.9 5.1 2 6.3 3.5 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Lipoprotein_2 PF00921.12 CEH19027.1 - 0.079 12.9 1.1 0.1 12.5 0.8 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein PTS_2-RNA PF01885.11 CEH19028.1 - 2.9e-59 199.4 0.0 1.1e-35 122.6 0.0 2.5 1 1 1 2 2 2 2 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF3856 PF12968.2 CEH19028.1 - 0.054 13.3 0.9 6.3 6.6 0.0 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) Mgm101p PF06420.7 CEH19029.1 - 3.5e-81 270.5 0.0 4.2e-81 270.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Pex19 PF04614.7 CEH19030.1 - 1.5e-59 201.6 1.7 2.5e-59 200.9 0.2 1.8 1 1 1 2 2 2 1 Pex19 protein family GHMP_kinases_C PF08544.8 CEH19030.1 - 3.5 7.9 0.0 3.5 7.9 0.0 3.8 5 0 0 5 5 5 0 GHMP kinases C terminal Pheromone PF08015.6 CEH19030.1 - 6.1 7.7 9.3 22 5.9 6.4 2.0 1 0 0 1 1 1 0 Fungal mating-type pheromone MFS_1 PF07690.11 CEH19031.1 - 3.4e-18 65.5 49.5 7.6e-10 38.0 17.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CEH19031.1 - 1.3e-05 23.6 12.3 2.8e-05 22.5 8.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Dicty_REP PF05086.7 CEH19035.1 - 0.015 13.1 5.1 0.018 12.8 3.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Transglut_C PF00927.17 CEH19035.1 - 0.04 13.9 0.2 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain DUF4432 PF14486.1 CEH19038.1 - 0.043 12.3 1.8 0.12 10.8 1.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4432) APP_E2 PF12925.2 CEH19038.1 - 0.14 11.7 8.2 0.23 11.0 5.6 1.6 1 1 0 1 1 1 0 E2 domain of amyloid precursor protein SPX PF03105.14 CEH19038.1 - 0.26 11.0 4.6 0.29 10.8 3.2 1.1 1 0 0 1 1 1 0 SPX domain DUF4606 PF15379.1 CEH19038.1 - 0.26 11.3 5.7 0.29 11.2 3.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4606) DUF4275 PF14101.1 CEH19038.1 - 0.39 10.8 5.2 2.8 8.0 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4275) Vps53_N PF04100.7 CEH19040.1 - 1.6e-72 244.4 0.0 2.7e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.8 CEH19040.1 - 4.3e-07 28.4 0.1 1.1e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 zf-C2H2 PF00096.21 CEH19041.1 - 4.1e-09 36.2 60.3 0.07 13.5 1.2 9.9 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH19041.1 - 1.1e-08 34.7 65.9 0.043 14.1 0.8 10.5 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CEH19041.1 - 0.00012 22.1 2.0 0.12 12.5 0.0 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CEH19041.1 - 0.002 18.3 0.2 0.002 18.3 0.1 9.2 13 0 0 13 13 13 3 Zinc-finger double domain zf-met PF12874.2 CEH19041.1 - 0.023 14.9 1.0 3.2 8.0 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type P5CR_dimer PF14748.1 CEH19043.1 - 1e-24 86.5 2.3 1e-24 86.5 1.6 2.1 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CEH19043.1 - 3e-14 53.2 1.2 1.2e-10 41.6 0.0 3.0 3 1 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CEH19043.1 - 0.022 14.1 0.2 0.33 10.3 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF4530 PF15039.1 CEH19043.1 - 1.6 8.6 5.8 4.1 7.3 1.3 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4530) Aminotran_3 PF00202.16 CEH19046.1 - 2.8e-111 371.6 0.0 3.5e-111 371.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CEH19046.1 - 1.4e-05 24.4 0.0 3.6e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CEH19046.1 - 0.011 14.7 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DUF336 PF03928.9 CEH19047.1 - 6.4e-14 51.8 0.0 9.8e-14 51.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF336) FAD_binding_4 PF01565.18 CEH19050.1 - 1.7e-15 56.7 1.3 3e-15 55.8 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CEH19050.1 - 2.9e-07 30.3 0.3 6.9e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like HpcH_HpaI PF03328.9 CEH19051.1 - 7.8e-34 116.4 0.0 8.9e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 CEH19051.1 - 0.043 12.6 0.0 0.14 11.0 0.0 1.7 2 0 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain p450 PF00067.17 CEH19052.1 - 6.3e-62 209.5 0.0 8.2e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.3 CEH19053.1 - 2.4e-44 152.0 0.0 3.5e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase PAH PF02671.16 CEH19055.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 1 0 1 1 1 0 Paired amphipathic helix repeat MOR2-PAG1_N PF14222.1 CEH19057.1 - 2.6e-128 429.1 0.0 4.3e-128 428.4 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 CEH19057.1 - 1.2e-64 218.6 1.7 1.4e-64 218.4 0.1 1.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 CEH19057.1 - 3.4e-30 104.4 0.2 1.1e-14 53.1 0.0 3.5 3 1 0 3 3 3 3 Cell morphogenesis central region HHH PF00633.18 CEH19058.1 - 4.5e-05 22.9 0.2 0.00012 21.6 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 CEH19058.1 - 0.0046 17.1 1.0 0.21 11.8 0.1 1.4 1 1 1 2 2 2 2 Helix-hairpin-helix domain Transposase_20 PF02371.11 CEH19058.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family HEAT_2 PF13646.1 CEH19058.1 - 0.062 13.5 0.1 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 HEAT repeats Sad1_UNC PF07738.8 CEH19060.1 - 1.3e-22 80.0 0.0 3.3e-11 43.1 0.0 2.4 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal 3HCDH_N PF02737.13 CEH19063.1 - 2.4e-40 138.1 1.3 2.6e-39 134.7 0.9 2.1 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CEH19063.1 - 2e-33 114.6 0.1 1e-32 112.3 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF2813 PF11398.3 CEH19063.1 - 0.0033 16.5 0.0 0.0043 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) PhyH PF05721.8 CEH19064.1 - 1.6e-46 158.9 0.0 6.1e-45 153.8 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Chorion_2 PF03964.10 CEH19064.1 - 0.069 13.7 9.2 0.062 13.8 0.9 2.5 2 0 0 2 2 2 0 Chorion family 2 His_Phos_2 PF00328.17 CEH19065.1 - 5e-38 131.3 0.0 7e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ist1 PF03398.9 CEH19066.1 - 1.1e-47 161.5 3.3 1.4e-47 161.2 2.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway bZIP_1 PF00170.16 CEH19067.1 - 4.9e-08 32.8 15.7 9.3e-08 31.9 10.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CEH19067.1 - 3.7e-05 23.4 17.0 0.00022 20.9 11.3 2.2 1 1 1 2 2 2 1 Basic region leucine zipper IncA PF04156.9 CEH19067.1 - 0.0038 16.8 0.8 0.0038 16.8 0.5 1.7 2 0 0 2 2 2 1 IncA protein DivIC PF04977.10 CEH19067.1 - 0.025 14.0 3.9 0.05 13.0 2.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Seryl_tRNA_N PF02403.17 CEH19067.1 - 0.15 12.1 5.2 0.3 11.0 3.6 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Zn_clus PF00172.13 CEH19069.1 - 3e-07 30.2 12.6 5.1e-07 29.4 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TTSSLRR PF12468.3 CEH19070.1 - 0.028 13.9 1.1 0.028 13.9 0.8 2.0 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Spo7_2_N PF15407.1 CEH19070.1 - 2.8 7.4 7.1 2.2 7.7 0.4 2.2 2 0 0 2 2 2 0 Sporulation protein family 7 HLH PF00010.21 CEH19073.1 - 3.6e-14 52.2 0.3 7.9e-14 51.0 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAM74 PF15026.1 CEH19073.1 - 0.33 10.5 4.4 7.9 6.1 0.3 2.6 2 0 0 2 2 2 0 FAM74 protein NUDIX PF00293.23 CEH19076.1 - 0.014 15.0 0.3 0.026 14.1 0.2 1.4 1 0 0 1 1 1 0 NUDIX domain TolB_N PF04052.8 CEH19076.1 - 0.11 12.5 0.0 4.7 7.3 0.0 2.8 2 1 1 3 3 3 0 TolB amino-terminal domain MFS_1 PF07690.11 CEH19077.1 - 8.6e-28 97.0 33.9 8.6e-28 97.0 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily V_ATPase_I PF01496.14 CEH19077.1 - 0.051 11.4 0.8 0.51 8.1 0.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PFK PF00365.15 CEH19078.1 - 1.2e-165 549.4 3.8 1.4e-96 322.7 0.6 3.2 3 0 0 3 3 3 3 Phosphofructokinase PapJ PF14855.1 CEH19078.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Pilus-assembly fibrillin subunit, chaperone Myosin_head PF00063.16 CEH19081.1 - 3.7e-238 792.0 0.0 5.2e-238 791.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 CEH19081.1 - 1.2e-35 121.5 2.3 4.9e-35 119.5 1.6 2.2 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 CEH19081.1 - 1.7e-09 36.4 27.9 0.041 13.5 0.1 7.1 7 0 0 7 7 7 5 IQ calmodulin-binding motif TPR_MLP1_2 PF07926.7 CEH19081.1 - 0.003 17.2 4.8 0.003 17.2 3.4 2.6 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein AAA_22 PF13401.1 CEH19081.1 - 0.0034 17.5 0.0 0.017 15.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain GAS PF13851.1 CEH19081.1 - 0.027 13.6 14.3 0.056 12.6 9.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 CEH19081.1 - 0.036 14.1 2.6 0.1 12.7 1.3 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 CEH19081.1 - 0.062 13.2 6.4 0.08 12.8 0.4 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 CEH19081.1 - 0.15 11.1 8.1 0.17 11.0 2.8 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IFT57 PF10498.4 CEH19081.1 - 0.39 9.3 9.3 1.2 7.7 6.4 1.8 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.4 CEH19081.1 - 0.63 10.2 6.2 14 5.9 0.3 3.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 CEH19081.1 - 0.69 8.2 6.3 1.1 7.5 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ATP-synt_ab PF00006.20 CEH19082.1 - 5.8e-62 208.9 0.0 9.3e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEH19082.1 - 1.6e-24 86.5 0.2 2.8e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEH19082.1 - 8.8e-24 83.5 1.8 2.4e-23 82.1 1.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF258 PF03193.11 CEH19082.1 - 0.002 17.3 0.1 0.0036 16.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CEH19082.1 - 0.0044 16.4 0.1 0.01 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 CEH19082.1 - 0.0072 16.0 0.2 0.29 10.8 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CEH19082.1 - 0.0091 15.9 0.1 0.031 14.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 CEH19082.1 - 0.0093 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 CEH19082.1 - 0.017 15.2 0.0 0.17 12.0 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 CEH19082.1 - 0.018 14.1 0.2 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 CEH19082.1 - 0.022 14.4 0.2 0.063 12.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 CEH19082.1 - 0.04 12.7 0.6 0.09 11.6 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.1 CEH19082.1 - 0.052 13.6 0.0 0.16 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CEH19082.1 - 0.082 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 CEH19082.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 CEH19082.1 - 0.17 11.8 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain TRH PF05438.7 CEH19083.1 - 0.013 14.8 0.2 0.015 14.7 0.1 1.1 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) HLH PF00010.21 CEH19085.1 - 2.6e-13 49.4 0.2 4.5e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neur_chan_memb PF02932.11 CEH19086.1 - 2.2 8.0 6.1 3.4 7.4 4.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 CEH19086.1 - 6.1 5.1 8.0 8.7 4.6 5.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIP5K PF01504.13 CEH19087.1 - 9.7e-48 162.4 0.0 1.5e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF4310 PF14187.1 CEH19087.1 - 0.44 10.0 0.0 0.75 9.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) PQ-loop PF04193.9 CEH19089.1 - 2e-26 91.3 16.2 4e-14 51.9 0.2 3.0 3 0 0 3 3 3 2 PQ loop repeat DUF4231 PF14015.1 CEH19089.1 - 2.6 8.0 6.6 1.1 9.2 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) CBFD_NFYB_HMF PF00808.18 CEH19090.1 - 0.0039 17.2 0.0 0.0039 17.2 0.0 1.9 2 0 0 2 2 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.5 CEH19090.1 - 0.082 11.9 11.5 0.1 11.6 8.0 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.8 CEH19090.1 - 0.25 11.1 7.1 0.34 10.7 5.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.1 CEH19090.1 - 0.26 10.7 4.4 0.4 10.0 3.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 CEH19090.1 - 0.32 9.4 13.1 0.43 9.0 9.1 1.2 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 CEH19090.1 - 0.53 9.9 14.6 0.79 9.3 10.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.5 CEH19090.1 - 0.66 10.2 13.5 1.3 9.2 9.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4407 PF14362.1 CEH19090.1 - 2.5 6.9 9.6 3.4 6.5 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.12 CEH19090.1 - 3.3 6.4 4.3 5.2 5.7 3.0 1.3 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.7 CEH19090.1 - 4.2 6.5 9.6 6.5 5.9 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 CEH19090.1 - 8.8 4.1 17.2 12 3.6 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family Fasciclin PF02469.17 CEH19091.1 - 2.8e-21 75.8 0.3 1.5e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain BIR PF00653.16 CEH19092.1 - 4.3e-32 110.3 0.6 1.3e-19 70.3 0.1 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain p450 PF00067.17 CEH19093.1 - 8.4e-52 176.2 0.0 1.1e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ebp2 PF05890.7 CEH19093.1 - 0.0025 17.1 0.3 0.0039 16.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 KorB_C PF06613.6 CEH19093.1 - 0.022 14.1 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain COesterase PF00135.23 CEH19094.1 - 2.9e-31 108.7 0.0 1e-21 77.3 0.0 3.0 1 1 2 3 3 3 3 Carboxylesterase family OPT PF03169.10 CEH19095.1 - 8.3e-96 321.8 42.4 9.5e-96 321.6 29.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Axin_b-cat_bind PF08833.5 CEH19097.1 - 0.22 11.2 1.4 0.22 11.2 0.0 1.8 2 1 0 2 2 2 0 Axin beta-catenin binding domain ATP-grasp_2 PF08442.5 CEH19100.1 - 4.7e-72 241.6 0.7 7.4e-72 240.9 0.5 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CEH19100.1 - 3.7e-20 72.0 0.6 9.8e-20 70.7 0.4 1.8 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 CEH19100.1 - 1.2e-10 41.0 1.2 1.5e-10 40.6 0.2 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 CEH19100.1 - 0.00014 21.4 2.4 0.00014 21.4 1.7 2.0 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 CEH19100.1 - 0.029 14.1 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain MitMem_reg PF13012.1 CEH19101.1 - 1.2e-16 60.8 0.1 1.9e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CEH19101.1 - 1.1e-11 44.4 0.0 1.6e-10 40.7 0.0 2.4 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ras PF00071.17 CEH19102.1 - 1.7e-62 209.6 0.1 2e-62 209.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH19102.1 - 5.4e-20 72.0 0.0 7.7e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH19102.1 - 1.5e-12 47.0 0.0 2.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CEH19102.1 - 1.2e-06 28.5 0.0 1.5e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEH19102.1 - 1e-05 25.0 0.1 4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CEH19102.1 - 8.9e-05 22.6 0.0 0.00032 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 CEH19102.1 - 0.0014 17.8 0.1 0.0031 16.6 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CEH19102.1 - 0.0041 16.3 0.0 0.0058 15.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.1 CEH19102.1 - 0.0087 15.1 0.0 0.012 14.6 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.1 CEH19102.1 - 0.016 15.1 0.5 0.047 13.6 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 CEH19102.1 - 0.026 13.9 0.0 0.091 12.2 0.0 1.8 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CEH19102.1 - 0.03 14.6 0.3 0.042 14.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 CEH19102.1 - 0.034 13.3 0.0 0.081 12.1 0.0 1.6 2 1 1 3 3 3 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 CEH19102.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CEH19102.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CEH19102.1 - 0.094 12.6 0.1 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CEH19102.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MoCF_biosynth PF00994.19 CEH19103.1 - 8.3e-34 116.0 0.0 1.2e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain TAFII55_N PF04658.8 CEH19104.1 - 2.2e-46 157.3 0.0 4.6e-46 156.2 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region RepB-RCR_reg PF10723.4 CEH19104.1 - 0.096 12.4 2.5 0.26 11.0 1.7 1.8 1 0 0 1 1 1 0 Replication regulatory protein RepB GntP_permease PF02447.11 CEH19104.1 - 0.96 7.8 1.4 1.4 7.3 1.0 1.1 1 0 0 1 1 1 0 GntP family permease BING4CT PF08149.6 CEH19105.1 - 9.9e-32 108.3 0.0 4.7e-31 106.1 0.0 2.2 3 0 0 3 3 3 1 BING4CT (NUC141) domain Coatomer_WDAD PF04053.9 CEH19105.1 - 1.6e-06 27.2 0.0 2.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 CEH19105.1 - 6.2e-06 25.8 0.0 0.0043 16.8 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF1170 PF06663.8 CEH19105.1 - 0.18 11.7 4.1 0.23 11.3 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1170) Ras PF00071.17 CEH19108.1 - 7.6e-52 174.9 0.0 9.7e-52 174.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CEH19108.1 - 2.9e-20 72.9 0.0 4.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CEH19108.1 - 3.7e-12 45.8 0.0 5.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CEH19108.1 - 2.5e-06 26.8 0.0 3e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CEH19108.1 - 5.9e-05 22.5 0.0 0.00085 18.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CEH19108.1 - 0.001 19.2 0.8 0.014 15.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.5 CEH19108.1 - 0.0051 16.0 0.0 0.0075 15.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NACHT PF05729.7 CEH19108.1 - 0.021 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KaiC PF06745.8 CEH19108.1 - 0.039 13.0 0.1 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.4 CEH19108.1 - 0.04 13.4 0.0 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CEH19108.1 - 0.041 13.8 0.0 0.068 13.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 CEH19108.1 - 0.06 12.7 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 CEH19108.1 - 0.066 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_16 PF13191.1 CEH19108.1 - 0.098 12.6 6.0 0.029 14.3 0.7 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 CEH19108.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain YLP PF02757.12 CEH19109.1 - 9.7 6.3 6.9 0.57 10.0 0.4 2.3 2 1 0 1 1 1 0 YLP motif DAHP_synth_2 PF01474.11 CEH19110.1 - 1.9e-157 524.1 0.0 2.2e-157 523.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family IlvN PF07991.7 CEH19112.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Cation_ATPase_C PF00689.16 CEH19113.1 - 1.4e-32 112.7 8.8 1.4e-32 112.7 6.1 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEH19113.1 - 1.1e-22 81.5 0.3 3.1e-17 63.6 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CEH19113.1 - 6.4e-20 71.1 7.1 3.2e-16 59.0 0.1 3.1 3 1 1 4 4 4 2 E1-E2 ATPase Hydrolase_like2 PF13246.1 CEH19113.1 - 1.9e-16 59.7 0.0 3.7e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CEH19113.1 - 1.4e-12 46.8 1.2 1.9e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CEH19113.1 - 2.9e-06 27.5 4.1 8e-06 26.1 2.9 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEH19113.1 - 0.00068 19.2 0.5 0.0021 17.6 0.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 CEH19113.1 - 0.25 9.8 5.5 3.6 6.0 0.9 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) RVT_1 PF00078.22 CEH19114.1 - 1.4e-14 54.0 0.2 7.3e-14 51.6 0.2 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CEH19114.1 - 0.00023 20.9 3.4 0.00051 19.8 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CEH19114.1 - 0.022 14.8 3.0 0.17 11.9 0.0 2.9 2 0 0 2 2 2 0 Retrotransposon gag protein RNase_H2-Ydr279 PF09468.5 CEH19114.1 - 0.043 13.0 1.5 0.071 12.3 1.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Herpes_UL6 PF01763.11 CEH19114.1 - 0.052 11.7 2.7 0.079 11.1 1.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Asp_protease_2 PF13650.1 CEH19114.1 - 0.19 12.2 0.4 0.74 10.3 0.0 2.3 3 0 0 3 3 3 0 Aspartyl protease MerR-DNA-bind PF09278.6 CEH19114.1 - 1.9 8.9 4.8 1.4 9.3 0.0 2.8 2 0 0 2 2 2 0 MerR, DNA binding rve PF00665.21 CEH19115.1 - 7.1e-20 71.3 0.0 1.2e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Cytadhesin_P30 PF07271.6 CEH19116.1 - 0.015 14.6 0.1 0.027 13.7 0.1 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 rve PF00665.21 CEH19118.1 - 2.8e-20 72.6 0.0 7.8e-20 71.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 CEH19118.1 - 0.0063 16.0 0.1 0.42 10.1 0.0 2.9 2 0 0 2 2 2 1 Integrase core domain PHP PF02811.14 CEH19118.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.3 1 1 0 1 1 1 0 PHP domain Retrotrans_gag PF03732.12 CEH19119.1 - 0.00016 21.6 0.9 0.00049 20.1 0.3 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CEH19119.1 - 0.0016 18.2 3.5 0.0027 17.5 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF3116 PF11313.3 CEH19119.1 - 0.024 14.2 0.6 4.5 6.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3116) DUF4287 PF14117.1 CEH19119.1 - 0.061 13.0 0.1 44 3.8 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4287) zf-CCHC_2 PF13696.1 CEH19119.1 - 0.18 11.3 2.8 0.38 10.2 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Baculo_PEP_C PF04513.7 CEH19119.1 - 0.18 11.6 3.6 9.5 6.0 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spore_YtfJ PF09579.5 CEH19120.1 - 0.028 14.2 0.2 0.039 13.7 0.2 1.2 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Phage_tail_X PF05489.7 CEH19120.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Phage Tail Protein X Med15 PF09606.5 CEH19120.1 - 0.12 10.5 0.5 0.12 10.5 0.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal VID27 PF08553.5 CEH19121.1 - 3e-197 657.4 3.1 1.4e-142 476.6 0.0 3.0 1 1 1 2 2 2 2 VID27 cytoplasmic protein adh_short_C2 PF13561.1 CEH19121.1 - 7.6e-26 91.3 2.2 3.2e-25 89.3 0.7 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CEH19121.1 - 1.4e-25 90.1 1.7 3.6e-25 88.8 1.2 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CEH19121.1 - 2.5e-13 50.0 0.4 6.2e-13 48.8 0.3 1.7 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 CEH19121.1 - 0.0006 19.6 0.3 0.0016 18.3 0.2 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 CEH19121.1 - 0.0099 15.5 1.0 0.03 13.9 0.7 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CEH19121.1 - 0.068 12.2 0.1 0.16 11.0 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Rrp15p PF07890.7 CEH19122.1 - 2.5e-24 85.7 2.5 2.5e-24 85.7 1.8 3.3 1 1 0 2 2 2 1 Rrp15p Zn_clus PF00172.13 CEH19123.1 - 0.00021 21.1 4.7 0.00038 20.2 3.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 CEH19124.1 - 1.9e-69 234.8 0.0 2.9e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CEH19124.1 - 7e-11 42.1 0.1 1.6e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEH19124.1 - 4.1e-05 22.8 0.1 7.9e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_transf_20 PF00982.16 CEH19125.1 - 1.3e-124 416.2 0.0 3.4e-124 414.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CEH19125.1 - 3e-75 252.1 0.0 4.9e-75 251.4 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 CEH19125.1 - 4.4e-05 23.1 0.0 0.058 12.9 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase rve_3 PF13683.1 CEH19125.1 - 0.034 13.6 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Nefa_Nip30_N PF10187.4 CEH19126.1 - 0.00074 19.6 0.3 0.00074 19.6 0.2 3.6 4 0 0 4 4 4 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF3808 PF10300.4 CEH19126.1 - 0.11 11.0 1.6 0.2 10.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) L31 PF09784.4 CEH19126.1 - 2.6 8.1 6.6 23 5.0 0.0 3.7 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 Med9 PF07544.8 CEH19126.1 - 3.5 7.4 12.2 0.39 10.4 0.3 3.7 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.5 CEH19126.1 - 7.2 6.7 11.9 27 4.8 0.1 3.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Tmemb_14 PF03647.8 CEH19127.1 - 3.4e-19 69.0 6.2 4.1e-19 68.7 4.3 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C HMG_box PF00505.14 CEH19128.1 - 4.7e-05 23.5 1.4 5.7e-05 23.2 1.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CEH19128.1 - 0.00013 22.2 0.4 0.00016 21.9 0.3 1.1 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 CEH19128.1 - 0.0019 18.4 2.1 0.0021 18.2 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) YABBY PF04690.8 CEH19128.1 - 0.0027 17.9 0.3 0.0031 17.7 0.2 1.0 1 0 0 1 1 1 1 YABBY protein P63C PF10546.4 CEH19128.1 - 0.038 13.9 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 P63C domain Toxin_45 PF15524.1 CEH19128.1 - 0.056 13.5 0.2 0.063 13.4 0.2 1.0 1 0 0 1 1 1 0 Putative toxin 45 MOZ_SAS PF01853.13 CEH19130.1 - 2.4e-79 264.9 0.0 3.8e-79 264.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 CEH19130.1 - 7.3e-18 64.0 20.1 3.3e-11 42.6 2.9 3.3 2 1 1 3 3 3 2 PHD-finger DPBB_1 PF03330.13 CEH19131.1 - 1.1e-05 25.3 0.2 3.6e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CEH19131.1 - 0.00021 20.9 0.1 0.00046 19.8 0.1 1.5 1 0 0 1 1 1 1 Barwin family DUF2890 PF11081.3 CEH19131.1 - 0.047 13.7 4.5 0.061 13.3 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 CEH19131.1 - 0.098 10.6 5.9 0.12 10.3 4.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CEH19131.1 - 0.11 10.3 7.3 0.14 10.0 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family FadA PF09403.5 CEH19131.1 - 0.15 12.0 2.6 0.22 11.5 1.8 1.3 1 0 0 1 1 1 0 Adhesion protein FadA SelP_N PF04592.9 CEH19131.1 - 2.2 7.6 7.8 3.5 6.9 5.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PLDc PF00614.17 CEH19132.1 - 2.2e-15 55.8 0.1 4.7e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CEH19132.1 - 2.1e-11 43.6 0.0 2.8e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 CEH19132.1 - 4.7e-09 36.0 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 PX domain CUE PF02845.11 CEH19133.1 - 6e-14 51.2 0.2 1.9e-13 49.5 0.1 1.9 2 0 0 2 2 2 1 CUE domain UBA PF00627.26 CEH19133.1 - 0.0032 17.2 0.1 0.0093 15.7 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Citrate_synt PF00285.16 CEH19134.1 - 1.3e-97 326.7 0.0 1.5e-97 326.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 CEH19134.1 - 0.019 14.4 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Robl_LC7 PF03259.12 CEH19136.1 - 4.1e-07 29.4 0.0 4.3e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 Roadblock/LC7 domain MFS_1 PF07690.11 CEH19140.1 - 1.3e-28 99.7 43.2 1.9e-28 99.2 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Arylesterase PF01731.15 CEH19141.1 - 0.0033 17.3 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 2 Arylesterase EMP24_GP25L PF01105.19 CEH19142.1 - 3.2e-40 137.7 0.0 3.8e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PGK PF00162.14 CEH19144.1 - 1.5e-149 497.7 0.5 1.7e-149 497.6 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase TFIIS_C PF01096.13 CEH19145.1 - 1e-20 73.0 3.2 1.3e-20 72.6 2.2 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 CEH19145.1 - 0.0023 17.6 0.6 0.0035 17.1 0.4 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 CEH19145.1 - 0.15 11.3 1.3 0.35 10.2 0.9 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding Ogr_Delta PF04606.7 CEH19145.1 - 0.26 10.9 3.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger PhnA_Zn_Ribbon PF08274.7 CEH19145.1 - 1.6 8.5 4.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon WD40 PF00400.27 CEH19147.1 - 8.5e-14 50.8 1.6 0.00019 21.1 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Coa1 PF08695.5 CEH19148.1 - 1.2e-21 76.4 0.1 3.1e-20 71.8 0.1 2.1 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 HATPase_c PF02518.21 CEH19150.1 - 7.2e-29 99.7 0.0 1.7e-28 98.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.5 CEH19150.1 - 5.7e-26 90.7 3.2 3.1e-09 36.8 0.1 5.8 4 1 0 4 4 4 4 PAS fold Response_reg PF00072.19 CEH19150.1 - 1.4e-25 89.4 0.0 3.4e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 CEH19150.1 - 2.7e-23 82.3 0.0 1.8e-12 47.5 0.0 4.5 4 0 0 4 4 4 3 PAS domain HisKA PF00512.20 CEH19150.1 - 7.3e-21 73.9 0.1 2.5e-20 72.2 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 CEH19150.1 - 4e-14 52.4 0.7 1e-13 51.1 0.5 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 CEH19150.1 - 4.2e-11 42.6 0.0 0.00093 18.9 0.0 5.2 5 0 0 5 5 5 2 PAS fold PAS_8 PF13188.1 CEH19150.1 - 0.0017 18.1 0.0 1 9.3 0.0 3.1 2 0 0 2 2 2 1 PAS domain PAS_7 PF12860.2 CEH19150.1 - 0.0093 15.9 0.3 5.7 6.9 0.0 3.8 3 0 0 3 3 3 1 PAS fold SMC_N PF02463.14 CEH19151.1 - 1.2e-61 207.8 0.0 2.6e-61 206.6 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CEH19151.1 - 9.7e-30 103.0 0.0 4.4e-29 100.8 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CEH19151.1 - 7.7e-13 49.0 2.9 4.4e-08 33.4 0.2 3.0 2 1 1 3 3 3 2 AAA domain AAA_29 PF13555.1 CEH19151.1 - 7.6e-08 31.7 0.0 2.1e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CEH19151.1 - 3.9e-06 26.2 20.5 0.0067 15.6 0.2 5.8 4 2 2 6 6 6 3 Reovirus sigma C capsid protein IncA PF04156.9 CEH19151.1 - 9.6e-05 22.0 107.4 0.013 15.1 14.2 6.6 4 1 1 5 5 5 3 IncA protein ADIP PF11559.3 CEH19151.1 - 0.00052 19.9 9.4 0.00052 19.9 6.5 8.3 5 2 3 8 8 7 1 Afadin- and alpha -actinin-Binding WEMBL PF05701.6 CEH19151.1 - 0.00077 18.0 0.7 0.00077 18.0 0.5 5.6 3 2 0 4 4 4 2 Weak chloroplast movement under blue light AAA_15 PF13175.1 CEH19151.1 - 0.0009 18.3 0.9 0.0009 18.3 0.6 3.6 4 1 0 4 4 4 1 AAA ATPase domain AAA_13 PF13166.1 CEH19151.1 - 0.0022 16.5 77.8 0.013 13.9 12.8 5.5 4 2 1 5 5 5 3 AAA domain TMF_DNA_bd PF12329.3 CEH19151.1 - 0.0032 17.2 8.7 0.0032 17.2 6.0 9.3 5 3 2 9 9 7 1 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 CEH19151.1 - 0.043 13.6 22.0 9.4 6.0 0.0 5.9 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.22 CEH19151.1 - 0.051 13.8 0.0 0.051 13.8 0.0 6.3 5 2 0 5 5 4 0 ABC transporter Laminin_II PF06009.7 CEH19151.1 - 0.21 11.3 56.4 0.033 13.9 3.4 7.5 4 2 3 7 7 7 0 Laminin Domain II AAA_17 PF13207.1 CEH19151.1 - 1.1 10.0 0.0 1.1 10.0 0.0 5.1 5 2 0 5 5 5 0 AAA domain DUF4201 PF13870.1 CEH19151.1 - 1.6 8.1 87.1 1.7 8.0 9.2 7.0 4 2 2 7 7 7 0 Domain of unknown function (DUF4201) AAA_23 PF13476.1 CEH19151.1 - 2.8 8.2 106.4 0.037 14.3 34.8 6.4 2 2 0 2 2 1 0 AAA domain DUF3584 PF12128.3 CEH19151.1 - 5 4.3 111.7 0.26 8.5 38.2 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) Bromodomain PF00439.20 CEH19152.1 - 8.6e-40 134.5 0.7 9.5e-19 67.1 0.0 2.4 2 0 0 2 2 2 2 Bromodomain DUF3724 PF12521.3 CEH19152.1 - 3.3 7.6 5.6 28 4.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) Trp_leader2 PF08056.6 CEH19154.1 - 0.22 11.5 1.7 0.7 9.9 1.2 1.9 1 0 0 1 1 1 0 Tryptophan operon leader peptide P53_TAD PF08563.6 CEH19155.1 - 0.086 11.9 0.9 0.14 11.2 0.6 1.3 1 0 0 1 1 1 0 P53 transactivation motif VirE2 PF07229.7 CEH19156.1 - 0.02 13.3 0.0 0.03 12.7 0.0 1.2 1 0 0 1 1 1 0 VirE2 Cnd1 PF12717.2 CEH19157.1 - 3.2e-62 209.5 2.5 8.6e-57 191.8 0.0 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 CEH19157.1 - 7.3e-30 103.8 1.6 4.5e-28 97.9 0.0 4.3 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term Adaptin_N PF01602.15 CEH19157.1 - 1.4e-08 33.5 0.7 5.3e-06 25.0 0.1 2.7 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 CEH19157.1 - 1.6e-07 31.4 1.2 0.0082 16.3 0.0 5.1 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 CEH19157.1 - 2.3e-05 24.0 3.9 2.6 8.3 0.1 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 CEH19157.1 - 0.0025 18.2 3.8 3.3 8.3 0.0 5.3 5 0 0 5 5 5 1 HEAT-like repeat Cnd3 PF12719.2 CEH19157.1 - 0.0065 15.4 2.6 0.0071 15.3 0.1 2.3 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 CEH19157.1 - 0.01 15.7 0.3 7.3 6.5 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Pkinase PF00069.20 CEH19158.1 - 1.8e-58 197.7 0.0 3e-35 121.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CEH19158.1 - 2e-26 92.6 0.0 5.3e-16 58.4 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.19 CEH19158.1 - 2.2e-10 40.8 0.7 1.1e-09 38.5 0.5 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 CEH19158.1 - 0.042 12.9 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIS PF01380.17 CEH19161.1 - 2.3e-60 201.9 0.2 8.7e-32 109.4 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CEH19161.1 - 1.8e-30 105.9 0.0 3.3e-20 72.1 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CEH19161.1 - 4.1e-19 68.8 0.0 1.2e-18 67.3 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CEH19161.1 - 2.8e-13 49.6 0.0 1.9e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CEH19161.1 - 1.2e-08 33.9 0.0 2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 CEH19161.1 - 0.018 14.7 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 SIS domain Plasmid_Txe PF06769.8 CEH19161.1 - 0.031 14.0 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 Plasmid encoded toxin Txe SH3_9 PF14604.1 CEH19162.1 - 4.6e-13 48.5 0.2 6.2e-13 48.1 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEH19162.1 - 5.5e-12 44.8 0.1 8e-12 44.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEH19162.1 - 2.9e-08 33.0 0.0 4.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain zf-CCHC PF00098.18 CEH19163.1 - 1.7e-17 62.4 22.4 1.6e-08 34.0 2.7 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 CEH19163.1 - 4.4e-07 29.5 7.0 0.024 14.3 0.3 3.3 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.1 CEH19163.1 - 0.26 10.8 15.0 0.47 9.9 1.6 3.4 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 CEH19163.1 - 4.6 6.9 12.6 1.9 8.2 0.3 3.2 3 0 0 3 3 3 0 Zinc knuckle Pmp3 PF01679.12 CEH19164.1 - 2.8e-14 52.5 3.4 4.1e-14 52.0 2.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Mito_carr PF00153.22 CEH19165.1 - 1.5e-37 127.1 6.2 1.5e-17 63.0 0.4 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein SHNi-TPR PF10516.4 CEH19165.1 - 0.017 14.3 1.5 0.93 8.7 0.2 2.3 2 0 0 2 2 2 0 SHNi-TPR Pyridoxal_deC PF00282.14 CEH19166.1 - 2.3e-52 177.7 0.0 3.9e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 CEH19166.1 - 2.8e-05 23.4 0.0 6.3e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CEH19166.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Pkinase PF00069.20 CEH19167.1 - 2.6e-70 236.5 0.0 4e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH19167.1 - 3.9e-40 137.5 0.0 5.7e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CEH19167.1 - 1.1e-13 50.9 0.0 6.7e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CEH19167.1 - 3.6e-05 22.8 0.0 6.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Aa_trans PF01490.13 CEH19168.1 - 0.0019 16.7 8.4 0.0019 16.7 5.8 1.7 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein CRF PF00473.12 CEH19169.1 - 6.5 6.9 5.7 28 4.8 1.2 2.3 2 0 0 2 2 2 0 Corticotropin-releasing factor family VRR_NUC PF08774.6 CEH19173.1 - 1.4e-16 60.3 0.1 3.2e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 VRR-NUC domain Pkinase PF00069.20 CEH19174.1 - 3.4e-64 216.5 0.0 4.4e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH19174.1 - 6.3e-28 97.5 0.0 8.2e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CEH19174.1 - 2.7e-05 23.2 0.0 4.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CEH19174.1 - 0.03 13.3 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEH19174.1 - 0.05 13.3 0.6 1.7 8.3 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Biotin_lipoyl PF00364.17 CEH19175.1 - 1.7e-05 24.3 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme 2-oxoacid_dh PF00198.18 CEH19176.1 - 5.8e-57 192.6 0.0 8.6e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 CEH19176.1 - 7.9e-15 54.2 0.2 2.3e-14 52.7 0.1 1.8 2 0 0 2 2 2 1 e3 binding domain HlyD PF00529.15 CEH19176.1 - 0.058 12.7 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 HlyD family secretion protein Got1 PF04178.7 CEH19177.1 - 1.4e-19 70.3 13.5 1.6e-19 70.1 9.4 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.8 CEH19177.1 - 6.1 6.9 16.5 1.3 9.0 7.1 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Apc5 PF12862.2 CEH19178.1 - 6.9e-12 45.0 2.1 2.5e-11 43.2 1.5 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 DUF2225 PF09986.4 CEH19178.1 - 0.034 13.6 0.3 0.057 12.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.7 CEH19178.1 - 0.49 11.1 4.2 0.68 10.6 0.9 2.8 2 0 0 2 2 2 0 Sel1 repeat TPR_12 PF13424.1 CEH19178.1 - 2.1 8.3 21.5 0.12 12.3 2.1 4.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CEH19178.1 - 7.7 6.6 20.7 4.4 7.4 0.6 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat Aa_trans PF01490.13 CEH19179.1 - 3.9e-24 84.8 28.3 2.5e-23 82.2 19.2 2.1 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF962 PF06127.6 CEH19179.1 - 0.15 11.9 1.7 0.39 10.6 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF962) UCR_UQCRX_QCR9 PF05365.7 CEH19179.1 - 6.5 6.4 6.8 16 5.2 0.1 3.6 4 0 0 4 4 4 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RNA_pol_Rbc25 PF08292.7 CEH19180.1 - 3.2e-30 104.8 0.0 4.2e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CEH19180.1 - 3.4e-16 59.1 0.1 8.3e-16 57.8 0.0 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CEH19180.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 2 0 0 2 2 2 0 S1 RNA binding domain DUF3348 PF11828.3 CEH19181.1 - 0.087 12.2 0.3 0.2 11.0 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3348) Acylphosphatase PF00708.13 CEH19181.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Acylphosphatase Pam17 PF08566.5 CEH19182.1 - 1.3e-35 122.6 0.0 1.4e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF3417 PF11897.3 CEH19182.1 - 0.11 12.5 0.4 0.14 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DASH_Dad2 PF08654.5 CEH19183.1 - 1.1e-22 79.9 0.0 1.7e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 NUDIX PF00293.23 CEH19185.1 - 6.9e-27 93.7 0.0 9.4e-27 93.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF2404 PF10296.4 CEH19186.1 - 7.1e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Sporozoite_P67 PF05642.6 CEH19186.1 - 0.56 7.9 2.4 4.1 5.1 1.4 2.0 1 1 1 2 2 2 0 Sporozoite P67 surface antigen Glyco_transf_22 PF03901.12 CEH19187.1 - 3.4e-79 266.8 15.8 6.4e-79 265.8 11.0 1.4 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Ku PF02735.11 CEH19188.1 - 1.2e-18 67.3 0.0 2.6e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 CEH19188.1 - 2.5e-14 53.2 0.0 6.3e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 CEH19188.1 - 0.0052 16.2 0.1 0.098 12.0 0.0 2.4 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain EamA PF00892.15 CEH19189.1 - 1.2e-14 54.4 8.8 1.2e-14 54.4 6.1 2.4 3 1 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 CEH19189.1 - 1.7e-05 24.9 8.2 1.7e-05 24.9 5.7 2.4 2 2 0 2 2 2 1 Multidrug resistance efflux transporter Gly-zipper_OmpA PF13436.1 CEH19189.1 - 0.037 13.6 0.5 0.074 12.7 0.3 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Use1 PF09753.4 CEH19190.1 - 8.2e-12 45.0 0.1 1.1e-10 41.3 0.0 2.3 2 0 0 2 2 2 1 Membrane fusion protein Use1 CDC73 PF05179.9 CEH19191.1 - 8.6e-39 133.5 5.4 4.6e-38 131.1 3.8 1.9 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Sec1 PF00995.18 CEH19194.1 - 1.4e-142 476.2 0.0 1.7e-142 475.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Snf7 PF03357.16 CEH19196.1 - 2.5e-35 121.3 13.9 2.9e-35 121.1 9.7 1.0 1 0 0 1 1 1 1 Snf7 Nuc-transf PF10127.4 CEH19196.1 - 0.034 13.5 0.8 0.062 12.6 0.5 1.4 1 0 0 1 1 1 0 Predicted nucleotidyltransferase Gluconate_2-dh3 PF13618.1 CEH19196.1 - 0.091 12.9 0.1 0.091 12.9 0.1 1.8 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Bac_GDH PF05088.7 CEH19196.1 - 0.14 9.5 7.5 0.17 9.2 5.2 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Rad1 PF02144.11 CEH19198.1 - 5.2e-59 199.2 0.0 7.4e-59 198.7 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 RNA_pol_Rpb8 PF03870.10 CEH19200.1 - 1.3e-05 25.4 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb8 DHQ_synthase PF01761.15 CEH19201.1 - 3.5e-87 291.6 0.0 4.8e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 CEH19201.1 - 3.2e-05 23.3 2.1 7.1e-05 22.2 1.4 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 CEH19201.1 - 0.018 13.6 7.0 0.054 12.1 4.9 1.7 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase FA_hydroxylase PF04116.8 CEH19203.1 - 0.0031 17.9 5.2 0.0031 17.9 3.6 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.23 CEH19205.1 - 1.4e-08 34.3 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2381 PF09544.5 CEH19205.1 - 0.02 14.0 0.1 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) RRM_1 PF00076.17 CEH19206.1 - 3e-34 116.4 0.0 1.4e-17 63.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH19206.1 - 2.8e-24 84.8 0.1 8.9e-12 44.8 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH19206.1 - 2.2e-14 53.0 0.0 4.6e-05 23.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CEH19206.1 - 2.8e-13 49.3 0.8 3.9e-08 32.8 0.0 3.4 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 CEH19206.1 - 0.00058 19.5 0.3 0.49 10.1 0.1 2.8 2 0 0 2 2 2 2 Limkain b1 PAM2 PF07145.10 CEH19206.1 - 0.094 12.2 2.0 0.92 9.1 0.0 2.7 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Nup35_RRM PF05172.8 CEH19206.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AAA_25 PF13481.1 CEH19207.1 - 2.3e-06 27.1 2.6 1.8e-05 24.2 1.8 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CEH19207.1 - 1.6e-05 24.5 0.2 1.6e-05 24.5 0.2 3.1 3 1 0 3 3 3 1 Part of AAA domain AAA_28 PF13521.1 CEH19207.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CEH19207.1 - 0.026 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CEH19207.1 - 0.026 14.7 0.0 0.066 13.4 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 CEH19207.1 - 0.05 12.2 0.2 2.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 CEH19207.1 - 0.075 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CEH19207.1 - 0.079 13.0 0.0 0.31 11.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 CEH19207.1 - 0.088 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Methyltransf_23 PF13489.1 CEH19208.1 - 1.4e-21 76.8 0.0 1.8e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH19208.1 - 2.1e-16 60.2 0.1 9.5e-16 58.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH19208.1 - 2.9e-15 56.5 0.1 8.9e-15 54.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH19208.1 - 6.2e-14 51.8 0.0 5.8e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CEH19208.1 - 3.9e-13 49.9 0.0 6.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH19208.1 - 4.5e-07 30.1 0.0 1.3e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CEH19208.1 - 1.1e-05 24.6 0.0 0.012 14.6 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CEH19208.1 - 9.4e-05 22.4 0.1 0.00038 20.4 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 CEH19208.1 - 0.00018 20.9 0.0 0.022 14.1 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.9 CEH19208.1 - 0.00042 19.7 0.1 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 CEH19208.1 - 0.00083 18.5 0.0 0.91 8.5 0.0 2.1 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 CEH19208.1 - 0.001 17.8 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) TPMT PF05724.6 CEH19208.1 - 0.0047 16.3 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 CEH19208.1 - 0.014 15.0 0.1 0.024 14.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 CEH19208.1 - 0.018 14.1 0.0 0.085 11.9 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 CEH19208.1 - 0.021 13.7 0.0 0.39 9.5 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase MetW PF07021.7 CEH19208.1 - 0.1 11.9 0.4 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PCMT PF01135.14 CEH19208.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4491 PF14898.1 CEH19213.1 - 5.2 7.2 6.0 1.7 8.8 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) PGM_PMM_I PF02878.11 CEH19214.1 - 3e-34 117.4 0.0 4.5e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CEH19214.1 - 1.2e-27 96.2 0.0 1.9e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CEH19214.1 - 1.5e-14 54.1 0.0 3.3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 3Beta_HSD PF01073.14 CEH19215.1 - 5.1e-67 225.5 0.0 2.8e-63 213.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CEH19215.1 - 9.1e-39 133.2 0.0 1.3e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CEH19215.1 - 5.9e-18 64.7 0.0 7.5e-14 51.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 CEH19215.1 - 1.6e-15 57.6 0.1 3.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CEH19215.1 - 1.7e-14 53.3 0.0 7.5e-14 51.2 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CEH19215.1 - 2e-10 40.0 1.1 3.4e-10 39.3 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CEH19215.1 - 6e-09 36.0 0.1 1.2e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 CEH19215.1 - 9.8e-06 24.9 0.5 1.6e-05 24.3 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 CEH19215.1 - 1.1e-05 25.2 0.1 2.2e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 KR domain ELFV_dehydrog PF00208.16 CEH19215.1 - 0.011 15.3 0.5 0.8 9.2 0.0 2.9 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.12 CEH19215.1 - 0.02 15.3 0.0 0.047 14.1 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 CEH19217.1 - 2e-08 34.3 1.5 3.9e-08 33.3 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CEH19217.1 - 2.5e-05 24.0 0.2 5.2e-05 22.9 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CEH19217.1 - 0.00028 20.4 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Retrotrans_gag PF03732.12 CEH19218.1 - 2.4e-06 27.5 0.1 4.4e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.22 CEH19220.1 - 1.7e-26 92.9 0.0 3.3e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.17 CEH19221.1 - 1.1e-77 255.6 0.9 4.9e-20 70.9 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH19221.1 - 5.8e-52 173.5 0.3 8.4e-15 54.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH19221.1 - 1.6e-39 133.5 0.0 6.9e-11 41.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CEH19221.1 - 1.5e-29 101.4 1.5 7.4e-29 99.2 1.1 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CEH19221.1 - 0.0013 18.5 7.3 0.1 12.4 0.6 4.1 5 0 0 5 5 5 2 RNA binding motif CbiG_mid PF11761.3 CEH19221.1 - 0.0032 17.6 0.0 7.6 6.8 0.0 3.2 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 CEH19221.1 - 0.012 15.3 0.1 3.3 7.5 0.0 3.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CEH19221.1 - 0.12 12.0 1.5 36 4.2 0.1 3.6 4 0 0 4 4 4 0 Limkain b1 Methyltransf_16 PF10294.4 CEH19222.1 - 1.7e-13 50.3 0.0 4.5e-10 39.2 0.0 3.1 1 1 0 1 1 1 1 Putative methyltransferase COG6 PF06419.6 CEH19223.1 - 5e-124 414.7 0.0 6.9e-124 414.2 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Tet_JBP PF12851.2 CEH19224.1 - 0.0049 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily RVT_1 PF00078.22 CEH19225.1 - 4.1e-07 29.5 0.0 1.1e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 CEH19225.1 - 0.021 14.5 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Med22 PF06179.7 CEH19226.1 - 2.7e-12 46.6 0.5 6.7e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex Sororin PF09666.5 CEH19226.1 - 0.033 14.3 1.3 0.036 14.2 0.1 1.7 2 0 0 2 2 2 0 Sororin protein TCO89 PF10452.4 CEH19226.1 - 3.8 6.2 11.5 0.47 9.2 3.7 2.0 2 0 0 2 2 2 0 TORC1 subunit TCO89 RIO1 PF01163.17 CEH19227.1 - 4.2e-67 225.1 0.0 4.2e-67 225.1 0.0 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CEH19227.1 - 3.1e-05 23.8 0.7 0.046 13.4 0.2 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CEH19227.1 - 0.014 14.4 0.7 0.077 12.0 0.5 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CEH19227.1 - 0.023 13.8 0.0 0.023 13.8 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain AMP-binding PF00501.23 CEH19228.1 - 1e-87 294.2 0.0 1.4e-87 293.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CEH19228.1 - 4.4e-09 37.1 0.1 9.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Chorismate_synt PF01264.16 CEH19229.1 - 5.1e-118 393.5 0.0 1.2e-65 221.2 0.0 2.0 1 1 1 2 2 2 2 Chorismate synthase Prefoldin_2 PF01920.15 CEH19230.1 - 1.3e-13 50.5 3.3 1.7e-13 50.2 2.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit CCDC144C PF14915.1 CEH19230.1 - 0.0061 15.5 1.6 0.0061 15.5 1.1 2.0 1 1 1 2 2 2 1 CCDC144C protein coiled-coil region CVNH PF08881.5 CEH19230.1 - 0.061 13.5 0.5 0.097 12.9 0.4 1.4 1 1 0 1 1 1 0 CVNH domain DUF4312 PF14189.1 CEH19230.1 - 0.071 12.9 0.9 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4312) Sec20 PF03908.8 CEH19230.1 - 0.42 10.3 4.2 0.44 10.2 0.8 2.1 2 0 0 2 2 2 0 Sec20 DivIC PF04977.10 CEH19230.1 - 0.59 9.6 6.8 1.3 8.5 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Enkurin PF13864.1 CEH19230.1 - 0.67 10.1 4.5 0.94 9.7 0.9 2.1 2 0 0 2 2 2 0 Calmodulin-binding TMF_DNA_bd PF12329.3 CEH19230.1 - 1.7 8.4 7.0 0.18 11.6 0.3 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ribosomal_L31e PF01198.14 CEH19231.1 - 6.5e-28 96.2 1.5 8.1e-28 95.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Ribosomal_S19e PF01090.14 CEH19232.1 - 4e-53 178.6 0.1 4.9e-53 178.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e SDA1 PF05285.7 CEH19232.1 - 0.18 11.0 11.0 0.22 10.7 7.6 1.1 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.6 CEH19232.1 - 0.43 10.3 5.7 0.56 10.0 3.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 CEH19232.1 - 1 8.5 8.1 1.2 8.3 5.6 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 CEH19232.1 - 4.4 5.1 11.9 4.7 5.0 8.3 1.0 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 CEH19232.1 - 10 5.7 15.6 14 5.2 10.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region tRNA-synt_1c PF00749.16 CEH19234.1 - 1.1e-101 339.6 0.0 1.8e-101 338.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 CEH19234.1 - 4.1e-27 94.7 0.1 7.1e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 CEH19234.1 - 4.7e-25 88.2 0.0 1e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 CEH19234.1 - 4.3e-06 27.3 4.0 4.3e-06 27.3 2.8 2.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Amidase PF01425.16 CEH19235.1 - 6.9e-88 295.4 2.7 4.1e-85 286.2 1.8 2.9 1 1 0 1 1 1 1 Amidase Aldo_ket_red PF00248.16 CEH19236.1 - 1.8e-44 151.7 0.0 2e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_5 PF13893.1 CEH19237.1 - 1.1e-09 37.9 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEH19237.1 - 2.2e-09 36.7 0.0 4.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH19237.1 - 3e-05 23.9 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CEH19237.1 - 0.00073 19.1 3.6 0.0014 18.2 2.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.1 CEH19237.1 - 0.0011 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Herpes_env PF01673.13 CEH19237.1 - 0.17 10.4 0.1 0.28 9.7 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein ZZ PF00569.12 CEH19238.1 - 4.5e-07 29.3 10.7 0.00041 19.8 1.2 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type FA_hydroxylase PF04116.8 CEH19239.1 - 1.1e-13 51.5 21.4 1.1e-13 51.5 14.8 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribonuc_P_40 PF08584.6 CEH19240.1 - 2.5e-20 72.6 0.0 4.6e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Phage_B PF02304.10 CEH19240.1 - 0.032 14.5 1.3 0.076 13.3 0.9 1.6 1 0 0 1 1 1 0 Scaffold protein B Dynamin_N PF00350.18 CEH19241.1 - 1.7e-41 141.8 0.0 3.5e-41 140.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 CEH19241.1 - 3.4e-05 22.7 0.0 0.00048 19.0 0.1 2.5 2 1 0 2 2 2 1 Dynamin central region Miro PF08477.8 CEH19241.1 - 0.0017 18.8 0.1 0.01 16.3 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 CEH19241.1 - 0.0047 16.8 0.0 0.016 15.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 CEH19241.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cir_N PF10197.4 CEH19242.1 - 8.7 6.4 8.1 7.1 6.7 0.0 3.2 3 0 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR ABC_membrane PF00664.18 CEH19248.1 - 4.9e-56 190.1 21.0 4.6e-29 101.6 4.8 2.4 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEH19248.1 - 2e-42 144.7 0.1 1.1e-25 90.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 CEH19248.1 - 3e-09 37.1 2.5 9.9e-05 22.3 1.3 3.0 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CEH19248.1 - 2.6e-08 33.3 4.4 0.00066 18.9 1.1 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CEH19248.1 - 7.3e-08 31.8 0.5 0.0059 16.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 CEH19248.1 - 2.1e-06 28.2 0.2 0.1 13.1 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 CEH19248.1 - 3.8e-06 26.4 0.0 0.12 11.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 CEH19248.1 - 7.7e-06 25.8 0.0 0.015 15.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 CEH19248.1 - 1.7e-05 24.0 0.1 0.11 11.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 CEH19248.1 - 2e-05 24.2 1.8 0.014 14.8 0.0 2.8 3 1 0 3 3 2 2 AAA-like domain AAA_21 PF13304.1 CEH19248.1 - 2e-05 24.6 0.0 0.33 10.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CEH19248.1 - 2.1e-05 24.6 1.1 0.62 10.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CEH19248.1 - 8.7e-05 23.3 0.0 0.039 14.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CEH19248.1 - 0.00027 19.9 0.0 0.2 10.5 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 CEH19248.1 - 0.00086 19.6 6.2 0.19 12.0 0.1 2.9 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 CEH19248.1 - 0.0022 17.6 3.7 0.72 9.4 0.1 2.9 3 0 0 3 3 3 2 NACHT domain cobW PF02492.14 CEH19248.1 - 0.0025 17.2 1.5 1 8.7 0.1 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CEH19248.1 - 0.0028 17.3 0.0 0.18 11.4 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 CEH19248.1 - 0.0059 16.3 0.9 0.37 10.4 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CEH19248.1 - 0.0062 16.3 7.0 0.12 12.2 0.0 3.2 4 0 0 4 4 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 CEH19248.1 - 0.0088 15.5 5.3 0.51 9.7 0.0 2.8 3 0 0 3 3 2 2 FtsK/SpoIIIE family ArgK PF03308.11 CEH19248.1 - 0.016 13.9 0.5 0.36 9.5 0.1 2.3 2 0 0 2 2 2 0 ArgK protein DUF87 PF01935.12 CEH19248.1 - 0.025 14.3 0.1 0.025 14.3 0.1 2.3 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 CEH19248.1 - 0.026 13.5 0.0 1 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 CEH19248.1 - 0.047 12.7 8.7 0.68 9.0 0.1 2.9 3 0 0 3 3 3 0 Zeta toxin DUF815 PF05673.8 CEH19248.1 - 0.058 12.3 0.3 2.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) GTP_EFTU PF00009.22 CEH19248.1 - 0.061 12.7 0.1 13 5.1 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 CEH19248.1 - 0.082 12.4 0.1 6.6 6.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 CEH19248.1 - 0.11 12.0 0.3 8.6 5.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 CEH19248.1 - 0.11 12.7 0.0 28 4.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 CEH19248.1 - 0.15 11.9 7.1 2.5 7.9 0.0 3.6 4 0 0 4 4 3 0 AAA domain Pox_A32 PF04665.7 CEH19248.1 - 0.21 10.8 2.0 0.67 9.1 0.0 2.5 3 0 0 3 3 3 0 Poxvirus A32 protein Septin PF00735.13 CEH19248.1 - 0.28 10.1 0.2 6.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Septin NB-ARC PF00931.17 CEH19248.1 - 0.3 9.9 1.4 0.87 8.3 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.1 CEH19248.1 - 0.99 9.7 9.9 1.4 9.2 0.5 3.2 3 1 0 3 3 2 0 AAA domain GSH_synth_ATP PF03917.12 CEH19249.1 - 9.2e-65 218.6 0.0 1.2e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CEH19249.1 - 2.5e-25 88.5 1.8 2.6e-14 53.1 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic glutathione synthase DUF202 PF02656.10 CEH19250.1 - 0.0075 16.4 8.8 0.11 12.7 0.2 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF202) WND PF07861.6 CEH19250.1 - 0.013 14.5 0.8 0.026 13.5 0.6 1.4 1 0 0 1 1 1 0 WisP family N-Terminal Region HA2 PF04408.18 CEH19254.1 - 2.3e-29 101.3 0.1 4.4e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CEH19254.1 - 1.3e-22 79.7 0.0 3.4e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CEH19254.1 - 3.8e-11 42.7 0.0 9e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CEH19254.1 - 1.1e-07 31.5 0.2 2.5e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CEH19254.1 - 1.3e-06 28.6 0.0 3.7e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CEH19254.1 - 0.0068 15.3 0.0 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 CEH19254.1 - 0.0079 16.0 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CEH19254.1 - 0.018 14.7 1.1 0.045 13.5 0.4 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain SRP54 PF00448.17 CEH19254.1 - 0.049 13.0 0.6 0.22 10.9 0.4 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain KaiC PF06745.8 CEH19254.1 - 0.049 12.7 0.0 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.4 CEH19254.1 - 0.057 12.3 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 CEH19254.1 - 0.09 12.0 0.1 0.57 9.3 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein ABC_tran PF00005.22 CEH19254.1 - 0.12 12.7 0.0 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 ABC transporter 2-Hacid_dh_C PF02826.14 CEH19255.1 - 2.5e-50 170.0 0.0 3.8e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CEH19255.1 - 8.2e-33 112.6 0.0 1.1e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CEH19255.1 - 0.00021 21.1 0.0 0.00068 19.5 0.0 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 CEH19255.1 - 0.092 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 CEH19255.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 ACT domain tRNA-synt_1g PF09334.6 CEH19256.1 - 2.8e-96 322.5 0.1 4.6e-84 282.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CEH19256.1 - 2.3e-13 49.0 0.1 3.1e-09 35.3 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CEH19256.1 - 9.6e-07 28.2 1.8 0.0065 15.6 0.0 3.6 4 0 0 4 4 4 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 CEH19256.1 - 1.5e-05 24.7 0.1 3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DALR_1 PF05746.10 CEH19256.1 - 0.00037 20.4 0.0 0.00074 19.4 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Toprim_4 PF13662.1 CEH19256.1 - 0.16 12.0 1.1 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Toprim domain SRP19 PF01922.12 CEH19257.1 - 4e-18 65.7 0.0 6.9e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein DsbD_2 PF13386.1 CEH19258.1 - 0.044 13.5 0.7 0.055 13.2 0.5 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Condensation PF00668.15 CEH19259.1 - 0.0039 16.0 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain ABC_tran PF00005.22 CEH19260.1 - 2.6e-43 147.6 0.1 6e-21 75.1 0.2 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CEH19260.1 - 6.1e-32 111.1 13.4 1.5e-20 73.7 3.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CEH19260.1 - 2.4e-11 43.2 5.2 0.00041 19.6 0.1 4.2 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CEH19260.1 - 2.5e-10 40.6 2.3 2.1e-05 24.5 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 CEH19260.1 - 3.6e-10 40.2 1.0 0.078 12.9 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CEH19260.1 - 6.6e-09 35.1 0.6 0.00053 19.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CEH19260.1 - 6.3e-08 32.2 0.0 0.0064 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CEH19260.1 - 1.3e-07 31.8 0.2 0.0006 19.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CEH19260.1 - 2.1e-07 30.6 0.0 0.0071 15.8 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 CEH19260.1 - 2.3e-07 30.1 0.0 0.0074 15.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 CEH19260.1 - 5e-05 22.8 5.0 0.039 13.4 0.1 3.3 2 1 0 3 3 3 1 AAA-like domain MMR_HSR1 PF01926.18 CEH19260.1 - 0.0002 21.3 0.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CEH19260.1 - 0.00037 20.9 0.1 0.5 10.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 CEH19260.1 - 0.00046 20.5 0.0 0.085 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CEH19260.1 - 0.00046 20.0 0.0 0.25 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 CEH19260.1 - 0.0011 18.5 0.1 0.017 14.6 0.0 2.6 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 CEH19260.1 - 0.0016 18.1 1.7 0.45 10.1 0.1 2.6 2 1 0 2 2 2 1 NACHT domain DUF2075 PF09848.4 CEH19260.1 - 0.0017 17.4 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 CEH19260.1 - 0.015 14.8 0.0 2.7 7.4 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CEH19260.1 - 0.021 15.0 0.0 5.1 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase T2SE PF00437.15 CEH19260.1 - 0.023 13.6 0.4 2.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.1 CEH19260.1 - 0.023 15.4 0.0 1.6 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 CEH19260.1 - 0.023 13.9 1.5 0.67 9.2 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 CEH19260.1 - 0.03 13.7 2.4 3.4 7.0 0.0 2.9 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 CEH19260.1 - 0.031 13.1 0.2 0.6 8.9 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 CEH19260.1 - 0.046 13.4 1.3 1.8 8.2 0.0 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Septin PF00735.13 CEH19260.1 - 0.049 12.6 0.1 0.53 9.2 0.0 2.0 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.18 CEH19260.1 - 0.051 13.4 0.2 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.12 CEH19260.1 - 0.058 13.1 4.1 1 9.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_14 PF13173.1 CEH19260.1 - 0.079 12.8 0.1 11 5.9 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CEH19260.1 - 0.081 12.8 0.0 17 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CEH19260.1 - 0.1 12.1 0.2 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CEH19260.1 - 0.11 11.0 0.8 5.9 5.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 CEH19260.1 - 0.13 11.9 0.2 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CEH19260.1 - 0.14 11.8 0.0 19 4.8 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 CEH19260.1 - 0.2 11.9 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 CEH19260.1 - 0.23 10.4 0.0 3 6.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.4 CEH19260.1 - 0.57 9.0 1.3 4.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 adh_short PF00106.20 CEH19261.1 - 1.7e-22 80.0 1.2 1.7e-22 80.0 0.8 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CEH19261.1 - 1.1e-12 47.9 0.4 1.1e-12 47.9 0.3 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CEH19261.1 - 3.3e-07 30.3 0.0 4.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CEH19261.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding DFP PF04127.10 CEH19261.1 - 0.029 13.9 0.3 0.094 12.3 0.2 1.8 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.13 CEH19261.1 - 0.11 12.1 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Longin PF13774.1 CEH19263.1 - 1.4e-14 53.4 0.0 2.5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CEH19263.1 - 7.5e-14 51.0 0.4 7.5e-14 51.0 0.3 1.6 2 0 0 2 2 2 1 Synaptobrevin Herpes_teg_N PF04843.7 CEH19263.1 - 0.071 12.5 0.1 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region DUF4407 PF14362.1 CEH19264.1 - 1.5 7.7 6.2 2.6 6.9 2.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ribosomal_L27 PF01016.14 CEH19265.1 - 1.4e-32 111.3 0.5 2e-32 110.8 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Npa1 PF11707.3 CEH19266.1 - 1.9e-54 184.8 0.0 4.7e-53 180.3 0.0 2.5 1 1 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 CEH19266.1 - 0.023 14.8 0.2 0.69 10.1 0.0 3.3 2 0 0 2 2 2 0 Creb binding Fes1 PF08609.5 CEH19267.1 - 1.6e-23 82.9 0.0 5.9e-23 81.1 0.0 2.1 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT PF02985.17 CEH19267.1 - 0.0015 18.4 1.2 3.7 7.8 0.1 4.1 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 CEH19267.1 - 0.0095 16.2 5.2 0.11 12.8 0.5 3.3 3 1 0 3 3 3 1 HEAT repeats Arm PF00514.18 CEH19267.1 - 0.012 15.3 0.8 0.26 11.1 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Serglycin PF04360.7 CEH19267.1 - 0.11 12.2 0.8 0.2 11.3 0.6 1.4 1 0 0 1 1 1 0 Serglycin Topoisom_bac PF01131.15 CEH19275.1 - 5.7e-74 249.3 0.0 1.7e-73 247.7 0.0 1.7 2 0 0 2 2 2 1 DNA topoisomerase zf-GRF PF06839.7 CEH19275.1 - 2.2e-26 91.5 15.5 1.1e-14 54.0 3.0 2.8 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC PF00098.18 CEH19275.1 - 1.9e-18 65.4 19.5 5.6e-08 32.3 1.4 3.7 3 0 0 3 3 3 3 Zinc knuckle Toprim PF01751.17 CEH19275.1 - 8.3e-17 61.0 0.0 2.4e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Toprim domain zf-CCHC_3 PF13917.1 CEH19275.1 - 3e-09 36.4 9.5 0.00091 18.9 0.2 3.6 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.1 CEH19275.1 - 8.2e-07 28.4 2.9 0.012 15.1 0.0 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.1 CEH19275.1 - 0.00062 19.2 13.2 0.38 10.2 0.2 3.7 3 0 0 3 3 3 3 GAG-polyprotein viral zinc-finger eIF3g PF12353.3 CEH19275.1 - 0.0066 16.3 13.7 0.39 10.6 0.4 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.1 CEH19275.1 - 1.7 8.3 10.5 2.5 7.8 0.2 3.4 3 0 0 3 3 3 0 Zinc knuckle BCS1_N PF08740.6 CEH19276.1 - 5.4e-51 172.8 0.6 9e-51 172.1 0.4 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CEH19276.1 - 4.3e-16 59.3 0.0 9.5e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEH19276.1 - 0.00041 21.1 0.0 0.00099 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CEH19276.1 - 0.0037 16.7 0.0 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CEH19276.1 - 0.0089 15.5 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 CEH19276.1 - 0.015 14.2 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 CEH19276.1 - 0.021 14.8 0.2 0.08 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 CEH19276.1 - 0.064 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CEH19276.1 - 0.098 12.7 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CEH19276.1 - 0.11 12.7 0.1 0.39 10.8 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_21 PF13304.1 CEH19276.1 - 0.11 12.3 1.9 0.51 10.2 1.4 1.8 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 CEH19276.1 - 0.15 11.1 0.0 0.46 9.5 0.0 1.8 2 0 0 2 2 2 0 KaiC DNA_pol_phi PF04931.8 CEH19277.1 - 9.2e-42 142.7 30.5 1.1e-29 102.8 12.6 3.3 3 0 0 3 3 3 3 DNA polymerase phi Phage_antiter_Q PF06323.6 CEH19278.1 - 0.0013 18.2 1.6 0.0014 18.0 1.1 1.0 1 0 0 1 1 1 1 Phage antitermination protein Q CR6_interact PF10147.4 CEH19278.1 - 0.016 14.5 3.2 0.02 14.2 2.2 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 HisKA_3 PF07730.8 CEH19278.1 - 0.017 15.4 7.2 0.12 12.7 1.2 2.2 1 1 1 2 2 2 0 Histidine kinase DUF1818 PF08848.6 CEH19278.1 - 0.028 14.4 1.6 0.029 14.4 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) V-SNARE PF05008.10 CEH19278.1 - 0.048 13.8 0.9 0.068 13.3 0.6 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus FUSC PF04632.7 CEH19278.1 - 6.2 5.1 7.3 6.7 5.0 5.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MIP PF00230.15 CEH19287.1 - 3.9e-48 163.9 15.3 5.2e-48 163.4 10.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein Glyoxalase_4 PF13669.1 CEH19289.1 - 0.037 14.0 0.1 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cytochrom_C_2 PF01322.15 CEH19289.1 - 0.04 14.4 3.0 0.093 13.2 2.1 1.6 1 0 0 1 1 1 0 Cytochrome C' Tape_meas_lam_C PF09718.5 CEH19289.1 - 0.084 12.8 4.4 6.6 6.7 0.2 3.3 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ApoL PF05461.6 CEH19289.1 - 0.16 11.2 3.5 0.23 10.6 2.4 1.1 1 0 0 1 1 1 0 Apolipoprotein L ATG_C PF09333.6 CEH19289.1 - 0.37 10.9 5.9 1.1 9.4 1.2 2.6 1 1 1 2 2 2 0 ATG C terminal domain Chlorosome_CsmC PF11098.3 CEH19289.1 - 0.61 9.7 10.0 1.1 8.9 6.2 2.0 1 1 0 1 1 1 0 Chlorosome envelope protein C Colicin PF01024.14 CEH19289.1 - 1.8 8.0 9.0 0.44 10.0 2.8 2.4 2 1 1 3 3 3 0 Colicin pore forming domain Pol_alpha_B_N PF08418.5 CEH19291.1 - 0.065 12.7 3.7 0.08 12.4 2.5 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF3043 PF11241.3 CEH19291.1 - 0.078 12.5 4.7 0.11 12.0 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4175 PF13779.1 CEH19291.1 - 0.15 9.7 14.6 0.2 9.3 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 CEH19291.1 - 0.54 9.9 5.6 0.58 9.8 3.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Tim54 PF11711.3 CEH19291.1 - 0.61 8.6 5.8 0.79 8.2 4.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Herpes_DNAp_acc PF04929.7 CEH19291.1 - 0.82 8.5 4.3 0.91 8.4 3.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RR_TM4-6 PF06459.7 CEH19291.1 - 7 6.4 9.3 8.1 6.2 6.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BPL_N PF09825.4 CEH19292.1 - 0.05 12.3 1.3 0.074 11.8 0.9 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal RXT2_N PF08595.6 CEH19292.1 - 1.7 8.4 11.1 0.22 11.3 3.9 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Gaa1 PF04114.9 CEH19293.1 - 1.6e-34 119.5 11.6 4.5e-14 52.0 0.1 5.0 3 1 2 5 5 5 4 Gaa1-like, GPI transamidase component SCO1-SenC PF02630.9 CEH19293.1 - 0.26 10.8 0.2 26 4.3 0.0 2.2 2 0 0 2 2 2 0 SCO1/SenC Helicase_C_2 PF13307.1 CEH19298.1 - 4.9e-54 182.7 0.0 1.2e-53 181.5 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CEH19298.1 - 3.2e-41 140.6 0.0 6.4e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 AAA_11 PF13086.1 CEH19298.1 - 0.017 14.7 1.4 0.087 12.3 0.9 2.2 1 0 0 1 1 1 0 AAA domain DUF3121 PF11319.3 CEH19298.1 - 0.24 10.8 0.0 0.24 10.8 0.0 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF3121) Hydrophobin PF01185.13 CEH19299.1 - 7.6e-17 61.5 8.0 1.1e-16 61.0 5.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF2296 PF10058.4 CEH19300.1 - 0.034 13.8 0.2 0.09 12.5 0.1 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Hydrophobin PF01185.13 CEH19301.1 - 5.1e-14 52.4 13.6 1.1e-13 51.4 9.4 1.6 1 0 0 1 1 1 1 Fungal hydrophobin OmpH PF03938.9 CEH19301.1 - 0.035 14.0 0.7 0.051 13.5 0.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Vps39_2 PF10367.4 CEH19302.1 - 1.7e-07 31.3 3.1 5.8e-07 29.6 0.0 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 CEH19302.1 - 0.13 12.2 0.5 3.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 NatB_MDM20 PF09797.4 CEH19303.1 - 1.7e-43 148.7 0.4 2.8e-43 148.0 0.1 1.5 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Abhydrolase_6 PF12697.2 CEH19306.1 - 5.8e-20 72.1 0.0 9.7e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CEH19306.1 - 7.8e-09 35.4 0.0 1.8e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH19306.1 - 0.00034 20.2 0.0 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEH19306.1 - 0.051 12.7 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thiolase_N PF00108.18 CEH19310.1 - 1.8e-97 325.4 3.5 2.6e-97 324.9 2.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CEH19310.1 - 1.3e-42 144.1 1.3 1.7e-41 140.4 0.5 2.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CEH19310.1 - 9.4e-06 25.2 2.3 0.00022 20.8 0.8 2.7 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CEH19310.1 - 2.8 7.6 9.6 2.9 7.5 0.2 3.2 3 1 1 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HpcH_HpaI PF03328.9 CEH19311.1 - 1.4e-40 138.5 0.0 1.9e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 CEH19311.1 - 8.5e-05 21.3 0.0 0.00012 20.7 0.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain EF1G PF00647.14 CEH19312.1 - 2e-40 136.7 0.0 4e-40 135.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CEH19312.1 - 1.8e-19 69.4 0.0 1.7e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CEH19312.1 - 1.1e-14 54.0 2.6 2.7e-06 27.1 0.0 2.9 3 1 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEH19312.1 - 4.1e-14 52.8 0.1 1.5e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CEH19312.1 - 3.1e-10 40.0 0.0 6.8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CEH19312.1 - 1.4e-09 38.0 0.0 2.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CEH19312.1 - 6.4e-06 26.0 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 CEH19312.1 - 0.00012 22.3 32.2 0.034 14.5 4.9 2.8 2 1 0 2 2 2 2 60s Acidic ribosomal protein DUF4611 PF15387.1 CEH19312.1 - 0.4 10.8 3.9 85 3.3 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) DUF490 PF04357.8 CEH19312.1 - 0.44 9.6 1.3 13 4.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF490) IGPD PF00475.13 CEH19314.1 - 7.5e-60 200.9 0.5 1e-59 200.5 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF2917 PF11142.3 CEH19314.1 - 0.083 12.0 0.1 0.33 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) zf-Tim10_DDP PF02953.10 CEH19315.1 - 2.7e-21 74.5 0.2 3.2e-21 74.3 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger LSM PF01423.17 CEH19316.1 - 3.9e-19 67.9 0.1 4.5e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain ABC_trans_N PF14510.1 CEH19317.1 - 4.6e-06 26.6 1.1 1.2e-05 25.2 0.2 2.0 1 1 1 2 2 2 1 ABC-transporter extracellular N-terminal ABC_tran PF00005.22 CEH19317.1 - 6.3e-05 23.2 0.1 0.00014 22.2 0.0 1.6 2 0 0 2 2 2 1 ABC transporter FtsK_SpoIIIE PF01580.13 CEH19317.1 - 0.036 13.5 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 CEH19317.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.19 CEH19318.1 - 2.7e-59 199.8 48.0 1.6e-34 118.9 13.4 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 CEH19318.1 - 2.1e-22 79.8 0.3 7.1e-17 61.9 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 CEH19318.1 - 1.5e-15 56.7 10.1 7.7e-15 54.4 0.0 3.5 4 0 0 4 4 2 2 CDR ABC transporter AAA_25 PF13481.1 CEH19318.1 - 1.4e-07 31.1 0.2 8.4e-07 28.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CEH19318.1 - 0.00016 21.7 0.0 0.76 9.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CEH19318.1 - 0.00063 19.7 1.1 0.0018 18.2 0.8 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CEH19318.1 - 0.0011 18.4 0.0 0.0032 16.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CEH19318.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 CEH19318.1 - 0.014 14.6 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CEH19318.1 - 0.018 15.2 0.3 0.3 11.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CEH19318.1 - 0.024 14.0 0.1 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 CEH19318.1 - 0.029 14.6 0.0 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CEH19318.1 - 0.054 13.1 0.7 0.13 11.9 0.5 1.6 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 CEH19318.1 - 0.075 13.8 0.0 0.24 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CEH19318.1 - 0.2 11.9 0.0 0.68 10.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CEH19318.1 - 0.22 11.0 0.2 0.52 9.8 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 CEH19318.1 - 0.68 8.9 0.0 1 8.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 CEH19318.1 - 0.92 8.8 2.6 2.3 7.5 0.3 2.5 3 0 0 3 3 3 0 AAA-like domain Shugoshin_N PF07558.6 CEH19319.1 - 0.0017 18.0 1.1 0.0028 17.3 0.8 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region UPF0197 PF05251.7 CEH19320.1 - 2.6e-08 34.0 8.4 7.9e-06 26.0 2.4 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0197) DctQ PF04290.7 CEH19320.1 - 0.02 14.6 2.2 0.86 9.3 0.0 2.4 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Fig1 PF12351.3 CEH19320.1 - 0.13 12.1 8.0 1.1 9.0 2.5 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4094 PF13334.1 CEH19320.1 - 0.31 11.4 3.5 2.2 8.7 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) DUF3483 PF11982.3 CEH19320.1 - 0.82 8.9 3.3 0.63 9.2 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) DUF1049 PF06305.6 CEH19320.1 - 0.84 9.1 0.0 0.84 9.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF3792 PF12670.2 CEH19320.1 - 3 7.7 10.0 1.8 8.4 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Aldose_epim PF01263.15 CEH19321.1 - 5.7e-11 42.0 0.2 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 2 Aldose 1-epimerase GCV_H PF01597.14 CEH19322.1 - 2.4e-39 133.7 0.1 2.8e-39 133.5 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 CEH19322.1 - 7.5e-05 22.2 0.3 0.00012 21.6 0.2 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 CEH19322.1 - 0.0037 16.9 0.1 0.0062 16.2 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain LysM PF01476.15 CEH19323.1 - 1.1e-09 37.9 0.0 0.00046 20.0 0.0 2.3 2 0 0 2 2 2 2 LysM domain Glyco_hydro_9 PF00759.14 CEH19324.1 - 1.3e-05 24.2 0.0 1.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF2648 PF10855.3 CEH19324.1 - 0.018 14.4 0.8 0.039 13.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) DUF4448 PF14610.1 CEH19324.1 - 0.033 13.6 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Glyco_hydro_9 PF00759.14 CEH19325.1 - 3.2e-24 85.6 0.2 4.5e-24 85.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Candida_ALS PF05792.8 CEH19325.1 - 1.7 8.8 6.2 9.3 6.4 1.2 2.9 2 0 0 2 2 2 0 Candida agglutinin-like (ALS) ig PF00047.20 CEH19329.1 - 0.049 13.7 1.1 0.88 9.7 0.1 2.3 1 1 1 2 2 2 0 Immunoglobulin domain Bac_surface_Ag PF01103.18 CEH19330.1 - 2.2e-19 70.1 0.0 3.5e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Surface antigen DUF3074 PF11274.3 CEH19331.1 - 1.1e-37 129.4 0.0 1.4e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) DUF455 PF04305.9 CEH19332.1 - 6.2e-83 277.9 0.0 1.2e-82 276.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 CEH19332.1 - 2e-05 24.0 0.0 7.2e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 CEH19332.1 - 0.0066 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain MiaE_2 PF13794.1 CEH19332.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like tRNA-synt_1g PF09334.6 CEH19333.1 - 6.9e-145 482.5 0.0 8.8e-145 482.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CEH19333.1 - 2.6e-10 38.9 0.1 6.1e-06 24.5 0.0 3.9 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) WHEP-TRS PF00458.15 CEH19333.1 - 8.8e-05 22.1 3.2 8.8e-05 22.1 2.2 2.1 2 0 0 2 2 2 1 WHEP-TRS domain Anticodon_1 PF08264.8 CEH19333.1 - 0.0037 17.0 0.2 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DZR PF12773.2 CEH19333.1 - 1.2 9.0 5.5 2.2 8.1 3.1 1.8 1 1 1 2 2 2 0 Double zinc ribbon ATP_bind_4 PF01902.12 CEH19334.1 - 1.6e-20 73.3 0.0 1.2e-17 64.0 0.0 3.1 2 1 0 2 2 2 1 ATP-binding region Ribonuc_L-PSP PF01042.16 CEH19334.1 - 4e-16 58.8 0.0 7e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP Stb3 PF10330.4 CEH19334.1 - 0.014 15.0 0.1 0.049 13.3 0.0 1.9 1 0 0 1 1 1 0 Putative Sin3 binding protein Metallophos PF00149.23 CEH19335.1 - 3.5e-43 147.3 0.1 4.5e-43 146.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RFC1 PF08519.7 CEH19336.1 - 4.2e-64 214.9 0.0 5.9e-48 162.5 0.0 2.9 3 0 0 3 3 3 2 Replication factor RFC1 C terminal domain BRCT PF00533.21 CEH19336.1 - 5.9e-12 45.5 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 CEH19336.1 - 8e-10 39.0 0.0 2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CEH19336.1 - 0.00028 19.7 0.0 0.0013 17.5 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CEH19336.1 - 0.00083 20.1 0.4 0.0021 18.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CEH19336.1 - 0.0019 18.5 0.0 0.0063 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CEH19336.1 - 0.0052 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CEH19336.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CEH19336.1 - 0.017 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.7 CEH19336.1 - 0.027 13.5 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CEH19336.1 - 0.045 13.9 0.0 0.19 11.9 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 CEH19336.1 - 0.056 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 CEH19336.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CEH19336.1 - 0.067 13.0 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PTCB-BRCT PF12738.2 CEH19336.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain LIM PF00412.17 CEH19338.1 - 1.1e-10 41.4 23.1 3.5e-05 23.7 1.1 5.8 6 1 0 6 6 6 3 LIM domain Ima1_N PF09779.4 CEH19338.1 - 0.066 13.7 0.6 0.41 11.1 0.1 2.6 2 0 0 2 2 2 0 Ima1 N-terminal domain CDP-OH_P_transf PF01066.16 CEH19339.1 - 3.4e-19 69.0 4.8 6.5e-19 68.1 3.3 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase CAP_N PF01213.14 CEH19340.1 - 2.9e-93 312.5 5.2 5.9e-93 311.5 3.6 1.5 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CEH19340.1 - 7.9e-62 207.2 0.8 1e-61 206.9 0.5 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 CEH19340.1 - 0.035 13.4 2.7 0.063 12.6 1.8 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C Formyl_trans_N PF00551.14 CEH19341.1 - 9.3e-33 113.2 0.1 1.7e-32 112.4 0.0 1.5 2 0 0 2 2 2 1 Formyl transferase ACT PF01842.20 CEH19341.1 - 5.4e-05 22.5 0.1 0.00024 20.4 0.0 2.2 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 CEH19341.1 - 0.0094 15.6 0.0 0.046 13.4 0.0 2.2 2 0 0 2 2 2 1 ACT domain Amino_oxidase PF01593.19 CEH19343.1 - 2.3e-41 142.3 3.3 9.1e-33 113.9 0.1 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CEH19343.1 - 1.7e-11 43.9 0.6 8.2e-11 41.7 0.4 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CEH19343.1 - 2.3e-08 33.3 1.1 3.9e-08 32.5 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CEH19343.1 - 5.2e-08 32.1 0.2 1.5e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CEH19343.1 - 1.1e-06 27.9 0.5 1.8e-06 27.3 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CEH19343.1 - 3e-06 27.2 0.0 6.8e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CEH19343.1 - 4.3e-05 23.8 0.6 0.0038 17.5 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEH19343.1 - 8.1e-05 21.8 1.4 0.0012 18.0 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CEH19343.1 - 0.00028 20.0 0.3 0.00043 19.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 CEH19343.1 - 0.00034 19.1 0.8 0.00066 18.2 0.6 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 CEH19343.1 - 0.00043 20.4 0.0 0.0011 19.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CEH19343.1 - 0.0011 17.9 0.4 0.0018 17.2 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 CEH19343.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF1353 PF07087.6 CEH19343.1 - 0.12 11.8 0.0 0.39 10.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1353) PAP_assoc PF03828.14 CEH19344.1 - 4.7e-15 55.2 0.1 8.7e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CEH19344.1 - 6.2e-06 26.4 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pkinase PF00069.20 CEH19345.1 - 1.4e-47 162.0 0.0 2e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH19345.1 - 1.7e-33 115.8 0.0 2.6e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CEH19345.1 - 1.8e-08 34.6 0.0 2.7e-07 30.8 0.0 3.0 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 CEH19345.1 - 5.2e-05 22.3 0.0 0.00022 20.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like AMP-binding PF00501.23 CEH19346.1 - 7.5e-32 110.2 0.6 1.3e-30 106.1 0.4 2.4 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CEH19346.1 - 2.1e-22 79.2 0.0 3.5e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CEH19346.1 - 5.2e-14 52.2 0.0 8.5e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CEH19346.1 - 5.6e-05 23.3 0.4 0.00025 21.2 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 CEH19346.1 - 0.00034 19.4 0.0 0.0006 18.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CEH19346.1 - 0.0031 17.4 0.6 0.014 15.3 0.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase SET PF00856.23 CEH19347.1 - 2.1e-21 76.9 9.0 4e-21 75.9 0.1 4.0 3 1 0 3 3 3 1 SET domain SRI PF08236.6 CEH19347.1 - 3.4e-19 68.5 1.1 7.5e-19 67.4 0.7 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain PGP_phosphatase PF09419.5 CEH19348.1 - 2.5e-38 131.0 0.0 4.9e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase End3 PF12761.2 CEH19348.1 - 0.056 13.0 0.2 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Hydrolase_like PF13242.1 CEH19348.1 - 0.14 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like PRTP PF01366.13 CEH19349.1 - 0.083 10.8 1.0 0.16 9.9 0.7 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein LRR_6 PF13516.1 CEH19349.1 - 0.11 12.6 15.0 9.8 6.6 0.0 7.4 8 1 0 8 8 8 0 Leucine Rich repeat Ebola_NP PF05505.7 CEH19349.1 - 0.18 9.8 3.1 0.31 9.0 2.1 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein LcrV PF04792.7 CEH19350.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein Lir1 PF07207.6 CEH19350.1 - 6.3 7.0 8.5 11 6.2 0.4 3.0 2 0 0 2 2 2 0 Light regulated protein Lir1 RRM_1 PF00076.17 CEH19352.1 - 3.8e-13 48.8 0.0 2.2e-10 39.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH19352.1 - 2.5e-10 40.0 0.0 2.9e-07 30.2 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH19352.1 - 2e-07 30.8 0.0 1.1e-05 25.3 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAD_binding_6 PF00970.19 CEH19353.1 - 1.6e-31 108.3 0.0 2.5e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CEH19353.1 - 9.7e-29 100.1 0.0 1.6e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CEH19353.1 - 1.2e-05 25.2 0.0 0.00037 20.4 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CEH19353.1 - 0.0071 16.2 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 Siderophore-interacting FAD-binding domain ZZ PF00569.12 CEH19354.1 - 0.018 14.5 1.5 0.041 13.4 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF605 PF04652.11 CEH19354.1 - 0.27 10.6 6.7 0.48 9.7 4.7 1.3 1 0 0 1 1 1 0 Vta1 like Sec63 PF02889.11 CEH19355.1 - 9.8e-80 268.1 0.0 1.7e-79 267.3 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CEH19355.1 - 2.7e-41 140.8 0.9 1.1e-29 103.1 0.2 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 CEH19355.1 - 1.2e-09 38.3 0.0 5.3e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CEH19355.1 - 3.3e-07 30.4 0.2 0.017 15.2 0.1 2.9 2 0 0 2 2 2 2 AAA domain Helicase_C PF00271.26 CEH19355.1 - 1.6e-06 27.9 0.0 6e-05 22.8 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CEH19355.1 - 0.072 11.8 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF2392 PF10288.4 CEH19356.1 - 2.3e-15 56.8 0.0 3.5e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Kelch_4 PF13418.1 CEH19357.1 - 2e-16 59.4 6.4 0.0043 16.7 0.0 5.9 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 CEH19357.1 - 1.8e-11 43.8 15.3 4.2e-05 23.5 0.1 6.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CEH19357.1 - 1.5e-09 37.6 0.0 0.009 15.9 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 CEH19357.1 - 8.8e-06 25.6 0.6 12 6.2 0.0 4.9 3 1 1 4 4 4 1 Kelch motif Kelch_1 PF01344.20 CEH19357.1 - 9.9e-05 21.8 0.2 3.8 7.1 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CEH19357.1 - 0.011 15.5 0.1 3.8 7.4 0.0 3.4 3 0 0 3 3 3 0 Kelch motif LRS4 PF10422.4 CEH19357.1 - 5.9 6.1 6.5 52 3.0 4.5 2.4 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 Tom37_C PF11801.3 CEH19359.1 - 3.3e-11 43.3 0.1 1.4e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Tom37 C-terminal domain GST_C_2 PF13410.1 CEH19359.1 - 0.0091 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CEH19359.1 - 0.027 14.9 0.2 0.077 13.4 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Nop14 PF04147.7 CEH19359.1 - 0.71 7.7 9.2 1 7.2 6.4 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 CEH19359.1 - 0.73 9.3 13.9 1.4 8.4 9.2 1.8 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 CEH19359.1 - 8.7 5.5 9.7 14 4.8 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein SCA7 PF08313.7 CEH19360.1 - 7.3e-27 92.7 0.6 1.6e-26 91.6 0.4 1.6 1 0 0 1 1 1 1 SCA7, zinc-binding domain ERM PF00769.14 CEH19360.1 - 0.00047 19.7 4.5 0.017 14.6 0.3 2.1 2 0 0 2 2 2 2 Ezrin/radixin/moesin family zf-C2HC_2 PF13913.1 CEH19360.1 - 0.001 18.6 0.2 0.0019 17.7 0.1 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type DUF1168 PF06658.7 CEH19360.1 - 0.51 9.8 16.6 0.3 10.5 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Pox_MCEL PF03291.11 CEH19361.1 - 8.6e-69 231.9 0.0 1.1e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_18 PF12847.2 CEH19361.1 - 1.2e-10 41.9 0.0 3.3e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH19361.1 - 9.6e-10 38.2 0.0 1.6e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CEH19361.1 - 3.2e-08 33.9 0.0 6.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH19361.1 - 3.9e-08 33.6 0.0 7.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH19361.1 - 1.2e-07 31.5 0.0 2.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH19361.1 - 1.4e-06 28.5 0.0 2.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CEH19361.1 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 CEH19361.1 - 0.0069 15.3 0.0 0.033 13.1 0.0 2.0 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 CEH19361.1 - 0.0076 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CEH19361.1 - 0.02 14.9 0.0 0.058 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.7 CEH19361.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DREV PF05219.7 CEH19361.1 - 0.45 9.3 0.0 0.72 8.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Mor PF08765.6 CEH19362.1 - 0.036 13.8 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Mor transcription activator family Gp_dh_C PF02800.15 CEH19363.1 - 1.6e-72 242.1 0.1 2.1e-72 241.6 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CEH19363.1 - 1.2e-60 203.8 0.1 2e-60 203.1 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADK PF00406.17 CEH19364.1 - 2.2e-57 193.1 0.0 2.8e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CEH19364.1 - 1.1e-13 50.6 0.0 2.3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CEH19364.1 - 1e-05 25.4 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CEH19364.1 - 8.2e-05 21.7 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CEH19364.1 - 0.0055 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CEH19364.1 - 0.011 15.8 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CEH19364.1 - 0.025 15.4 0.0 0.036 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 CEH19364.1 - 0.075 12.3 0.2 3.8 6.8 0.0 2.7 2 1 1 3 3 3 0 Thymidylate kinase AAA_5 PF07728.9 CEH19364.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FMO-like PF00743.14 CEH19365.1 - 6.4e-32 110.4 0.0 2.7e-22 78.6 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CEH19365.1 - 1.8e-16 60.8 0.0 4.8e-13 49.6 0.0 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CEH19365.1 - 2.9e-08 33.6 0.1 3.7e-07 30.0 0.1 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CEH19365.1 - 4.6e-07 29.9 0.0 5.2e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CEH19365.1 - 2.1e-06 26.9 0.0 0.00019 20.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CEH19365.1 - 2.5e-06 27.4 0.2 1e-05 25.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CEH19365.1 - 0.0015 17.4 0.2 0.5 9.1 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 CEH19365.1 - 0.0059 15.7 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 CEH19365.1 - 0.056 11.9 0.1 0.097 11.1 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 CEH19365.1 - 0.061 12.3 0.1 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 CEH19365.1 - 0.13 11.3 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 CEH19365.1 - 0.15 12.4 0.1 0.56 10.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sod_Fe_N PF00081.17 CEH19366.1 - 2.4e-33 114.2 1.8 3.2e-33 113.8 1.2 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 CEH19366.1 - 1.7e-16 59.9 0.0 3.5e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Membr_traf_MHD PF10540.4 CEH19367.1 - 5.5e-15 55.3 0.0 4.6e-14 52.3 0.0 2.6 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 CEH19367.1 - 2.8e-07 30.2 0.1 1.1e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 C2 domain RhoGEF PF00621.15 CEH19367.1 - 0.0092 15.8 0.0 0.039 13.8 0.0 2.1 1 1 0 1 1 1 1 RhoGEF domain AfaD PF05775.7 CEH19367.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein Ldh_1_N PF00056.18 CEH19368.1 - 1.4e-44 151.3 0.4 2.2e-44 150.6 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CEH19368.1 - 7.8e-37 126.6 0.0 1.1e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CEH19368.1 - 0.00015 20.5 0.0 0.00021 20.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Daxx PF03344.10 CEH19369.1 - 0.029 12.8 3.6 0.042 12.3 2.5 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 CEH19369.1 - 4.6 5.8 10.0 6.6 5.3 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HhH-GPD PF00730.20 CEH19370.1 - 1.2e-08 35.2 0.0 4.7e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein AT_hook PF02178.14 CEH19370.1 - 2.3 8.1 6.9 1.1 9.2 2.6 2.3 2 0 0 2 2 2 0 AT hook motif MFS_1 PF07690.11 CEH19371.1 - 7.1e-42 143.3 37.6 5.4e-40 137.1 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC1 PF03109.11 CEH19374.1 - 1.7e-31 108.6 0.0 2.6e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 CEH19374.1 - 0.0092 15.1 0.0 0.026 13.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Complex1_LYR PF05347.10 CEH19375.1 - 5.4e-10 38.9 0.5 1.2e-09 37.8 0.3 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CEH19375.1 - 3.3e-08 33.6 2.1 4e-08 33.3 0.2 2.1 3 0 0 3 3 3 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CEH19375.1 - 1.2e-07 32.1 0.8 2.4e-07 31.1 0.5 1.5 1 1 1 2 2 2 1 Complex1_LYR-like zf-primase PF09329.6 CEH19377.1 - 2.4e-08 33.4 0.5 2.4e-08 33.4 0.3 2.0 2 0 0 2 2 2 1 Primase zinc finger UPF0029 PF01205.14 CEH19378.1 - 1.9e-25 88.6 0.0 4.3e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 CEH19378.1 - 1.9e-10 40.6 0.4 1.2e-09 38.0 0.3 2.2 1 1 0 1 1 1 1 RWD domain Sporozoite_P67 PF05642.6 CEH19378.1 - 0.15 9.8 4.7 0.21 9.3 3.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mito_fiss_reg PF05308.6 CEH19378.1 - 1.1 8.6 8.9 0.056 12.8 2.2 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Pex14_N PF04695.8 CEH19378.1 - 7.8 6.5 7.7 1.4 8.9 1.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LRR_4 PF12799.2 CEH19379.1 - 6.1e-19 67.2 17.5 4.1e-06 26.2 1.0 5.2 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEH19379.1 - 1.2e-15 56.9 9.9 5.2e-10 38.9 1.9 4.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 CEH19379.1 - 1.6e-12 45.6 16.6 0.072 13.1 0.5 7.5 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 CEH19379.1 - 2.7e-08 32.6 17.1 2.3 8.8 0.0 7.6 7 0 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 CEH19379.1 - 6.4e-06 25.7 18.6 1.5 9.1 0.1 7.1 7 0 0 7 7 7 2 Leucine Rich repeat LRR_3 PF07725.7 CEH19379.1 - 0.22 11.3 2.4 6.5 6.7 0.2 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat DUF3640 PF12342.3 CEH19379.1 - 1.1 8.8 4.0 0.4 10.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) F-box-like PF12937.2 CEH19380.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 F-box-like Biotin_lipoyl PF00364.17 CEH19381.1 - 1.2e-21 76.1 1.6 2.3e-21 75.1 0.8 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 CEH19381.1 - 3.9e-10 39.1 0.0 7.8e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CEH19381.1 - 3.7e-05 23.2 0.5 0.00032 20.2 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like Clathrin PF00637.15 CEH19382.1 - 8.7e-25 86.9 0.1 1.9e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS WD40 PF00400.27 CEH19382.1 - 0.00054 19.7 0.7 0.011 15.6 0.1 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Vps39_1 PF10366.4 CEH19382.1 - 0.012 15.6 0.1 1.8 8.6 0.0 3.1 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 zf-rbx1 PF12678.2 CEH19382.1 - 0.25 11.4 0.2 1.1 9.3 0.1 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger FAT PF02259.18 CEH19383.1 - 4.5e-116 387.6 0.2 9.7e-116 386.5 0.1 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CEH19383.1 - 2.4e-57 194.0 0.0 4.1e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 CEH19383.1 - 1.3e-52 177.9 0.0 1.3e-51 174.7 0.0 2.8 4 0 0 4 4 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 CEH19383.1 - 1.5e-39 134.0 0.3 1.5e-39 134.0 0.2 3.0 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 CEH19383.1 - 7.7e-19 67.7 28.6 0.00029 21.0 0.1 11.1 7 2 4 11 11 10 6 HEAT repeats FATC PF02260.15 CEH19383.1 - 1.8e-15 56.0 0.6 4.8e-15 54.6 0.4 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 CEH19383.1 - 5.4e-12 44.7 17.4 0.05 13.7 0.0 10.7 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 CEH19383.1 - 0.00081 19.8 42.5 0.18 12.3 0.5 13.2 12 4 5 17 17 15 1 HEAT-like repeat TPR_16 PF13432.1 CEH19383.1 - 0.006 17.2 5.1 3.5 8.4 0.1 4.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CEH19383.1 - 0.0095 16.0 0.6 0.92 9.6 0.0 3.3 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Proteasom_PSMB PF10508.4 CEH19383.1 - 0.019 13.2 0.5 1.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit TPR_2 PF07719.12 CEH19383.1 - 0.024 14.5 3.9 6.2 7.0 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CEH19383.1 - 0.025 14.1 2.2 5.9 6.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CEH19383.1 - 0.14 11.9 2.5 6.7 6.7 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CEH19383.1 - 0.24 11.0 5.0 26 4.5 0.0 4.4 4 0 0 4 4 4 0 TPR repeat Adaptin_N PF01602.15 CEH19383.1 - 0.42 8.8 7.1 0.89 7.7 0.4 4.0 2 2 1 3 3 3 0 Adaptin N terminal region Methyltransf_11 PF08241.7 CEH19384.1 - 1.5e-15 57.4 0.0 4.2e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CEH19384.1 - 2.3e-09 37.1 0.0 3.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH19384.1 - 5.6e-09 36.2 0.0 1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH19384.1 - 7e-08 32.8 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CEH19384.1 - 1.4e-06 27.9 0.0 5.3e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH19384.1 - 6.8e-06 26.6 0.0 1.6e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CEH19384.1 - 0.00092 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CEH19384.1 - 0.013 15.5 0.0 0.052 13.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 CEH19385.1 - 7.2e-73 244.9 0.0 8.8e-73 244.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CEH19385.1 - 5.5e-32 110.8 0.0 7.1e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CEH19385.1 - 0.00015 20.8 0.0 0.00052 19.1 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CEH19385.1 - 0.00049 19.9 0.0 0.00099 18.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CEH19385.1 - 0.003 16.5 0.0 0.014 14.3 0.0 1.9 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CEH19385.1 - 0.026 13.8 0.0 0.059 12.7 0.0 1.5 2 0 0 2 2 2 0 RIO1 family DUF3987 PF13148.1 CEH19386.1 - 2.6 6.4 12.6 3.3 6.1 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RR_TM4-6 PF06459.7 CEH19386.1 - 4.6 7.0 9.7 5.7 6.7 6.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Methyltransf_31 PF13847.1 CEH19389.1 - 8.3e-12 44.9 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CEH19389.1 - 7.6e-11 42.5 0.0 1.1e-10 42.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CEH19389.1 - 1.5e-08 35.0 0.3 2.6e-08 34.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CEH19389.1 - 0.023 15.0 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CEH19389.1 - 0.029 14.3 0.1 0.078 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 CEH19389.1 - 0.031 13.9 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CEH19389.1 - 0.033 14.6 0.0 0.05 14.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CEH19389.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain AdoMet_MTase PF07757.8 CEH19389.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase 4HBT PF03061.17 CEH19390.1 - 1.1e-05 25.4 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 CEH19390.1 - 0.00026 20.8 0.0 0.073 12.8 0.0 1.4 1 1 1 2 2 2 2 Thioesterase-like superfamily DUF4442 PF14539.1 CEH19390.1 - 0.022 14.7 0.1 0.047 13.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) 4F5 PF04419.9 CEH19391.1 - 2e-08 34.8 12.2 2e-08 34.8 8.4 2.9 2 2 0 2 2 2 1 4F5 protein family Nebulin PF00880.13 CEH19391.1 - 0.55 9.9 4.7 3.3 7.4 0.0 3.1 2 1 1 3 3 3 0 Nebulin repeat GST_C_3 PF14497.1 CEH19392.1 - 0.064 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ion_trans PF00520.26 CEH19393.1 - 0.0035 16.6 14.9 0.39 9.9 10.3 2.4 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 CEH19393.1 - 0.04 12.3 8.4 0.018 13.4 0.3 2.2 2 0 0 2 2 2 0 Polycystin cation channel Cwf_Cwc_15 PF04889.7 CEH19393.1 - 0.86 9.2 5.5 1.2 8.7 3.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PLA2_B PF01735.13 CEH19394.1 - 2e-18 65.8 0.0 6.2e-09 34.5 0.6 2.3 2 0 0 2 2 2 2 Lysophospholipase catalytic domain Ribosomal_L30 PF00327.15 CEH19395.1 - 4.5e-08 32.5 0.1 7.2e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e L31 PF09784.4 CEH19396.1 - 7.3e-44 148.0 0.1 8.4e-44 147.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 UQ_con PF00179.21 CEH19397.1 - 1.6e-43 147.5 0.0 1.8e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CEH19397.1 - 0.0021 17.8 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Filament PF00038.16 CEH19398.1 - 4.3 6.7 119.9 0.073 12.5 11.7 5.7 1 1 4 5 5 5 0 Intermediate filament protein Per1 PF04080.8 CEH19399.1 - 3.1e-95 318.6 0.0 4.1e-95 318.2 0.0 1.2 1 0 0 1 1 1 1 Per1-like Sas10 PF09368.5 CEH19399.1 - 0.11 12.6 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Sas10 C-terminal domain zf-C2H2 PF00096.21 CEH19400.1 - 3.9e-07 30.0 16.6 0.00033 20.8 0.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CEH19400.1 - 8.8e-06 25.7 10.9 0.0011 19.0 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CEH19400.1 - 9.6e-06 25.6 5.1 9.6e-06 25.6 3.5 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CEH19400.1 - 0.085 13.0 5.1 12 6.1 2.2 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CEH19400.1 - 1 9.3 5.8 0.22 11.4 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger 2OG-FeII_Oxy_2 PF13532.1 CEH19401.1 - 5.4e-28 98.1 0.0 1.1e-27 97.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ubiquitin_2 PF14560.1 CEH19401.1 - 0.001 19.2 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain UIM PF02809.15 CEH19401.1 - 0.0064 15.9 17.4 0.074 12.6 1.4 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif Glyoxal_oxid_N PF07250.6 CEH19401.1 - 0.13 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Mago-bind PF09282.5 CEH19401.1 - 0.22 11.1 1.6 1.2 8.8 0.2 2.5 2 0 0 2 2 2 0 Mago binding Ribosomal_S6 PF01250.12 CEH19402.1 - 8.8e-10 38.3 0.0 1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Vac_ImportDeg PF09783.4 CEH19403.1 - 1.9e-56 190.3 0.0 1.8e-50 170.8 0.0 2.2 2 0 0 2 2 2 2 Vacuolar import and degradation protein NPR2 PF06218.6 CEH19404.1 - 2.7e-94 316.3 0.4 1.4e-44 152.4 0.4 4.1 3 1 1 4 4 4 4 Nitrogen permease regulator 2 NPR3 PF03666.8 CEH19404.1 - 0.066 11.7 0.4 1.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 GTP_EFTU PF00009.22 CEH19405.1 - 3.9e-32 111.2 2.2 3.3e-24 85.3 1.0 3.2 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CEH19405.1 - 1.2e-24 86.2 1.0 2.6e-24 85.2 0.7 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CEH19405.1 - 7e-06 26.0 1.4 0.02 15.0 0.0 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CEH19405.1 - 1.4e-05 25.0 0.0 4.1e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CEH19405.1 - 0.019 14.2 0.0 3.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Miro PF08477.8 CEH19405.1 - 0.031 14.7 0.1 0.16 12.4 0.0 2.2 1 1 1 2 2 2 0 Miro-like protein DUF3506 PF12014.3 CEH19407.1 - 2.7e-08 33.7 0.0 3.2e-07 30.2 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 CEH19407.1 - 0.0031 17.2 0.1 0.0079 15.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CEH19407.1 - 0.0065 16.1 0.5 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 F-box domain Na_Ca_ex PF01699.19 CEH19408.1 - 1.2e-23 83.3 31.7 9.7e-13 47.9 6.3 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 CEH19408.1 - 1.1e-12 48.1 8.4 1.1e-12 48.1 5.8 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF307) Ufd2P_core PF10408.4 CEH19409.1 - 6e-161 536.8 0.0 7.5e-161 536.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CEH19409.1 - 3.2e-26 91.1 2.0 2.1e-25 88.4 0.3 2.9 3 0 0 3 3 3 1 U-box domain CRAL_TRIO_2 PF13716.1 CEH19410.1 - 1.5e-31 109.2 0.0 3.3e-31 108.2 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 CEH19410.1 - 5e-24 84.6 0.0 8.1e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 CEH19410.1 - 6e-06 25.8 0.1 3e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 CRAL/TRIO domain Glyco_transf_25 PF01755.12 CEH19410.1 - 0.36 10.4 0.0 0.56 9.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Rtf2 PF04641.7 CEH19411.1 - 1.5e-49 168.5 2.2 1.5e-49 168.5 1.6 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger Asp PF00026.18 CEH19412.1 - 1.5e-34 119.6 0.2 2.2e-34 119.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CEH19412.1 - 3.6e-06 27.0 0.2 3.6e-06 27.0 0.2 2.5 4 0 0 4 4 4 1 Xylanase inhibitor N-terminal SKG6 PF08693.5 CEH19412.1 - 0.015 14.6 6.7 0.029 13.6 4.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3042 PF11240.3 CEH19412.1 - 0.098 12.4 2.2 0.28 11.0 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DUF3188 PF11384.3 CEH19412.1 - 0.31 10.6 4.1 0.66 9.5 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Peptidase_M28 PF04389.12 CEH19414.1 - 1.9e-29 102.6 0.0 2.9e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 adh_short PF00106.20 CEH19415.1 - 8.1e-28 97.4 4.1 1.1e-27 97.0 2.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CEH19415.1 - 2.5e-22 79.8 2.2 3.2e-22 79.4 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CEH19415.1 - 3.4e-10 39.8 4.5 7.7e-10 38.7 3.1 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CEH19415.1 - 0.041 12.7 0.2 0.065 12.1 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Hydrolase_like PF13242.1 CEH19416.1 - 5.3e-05 22.8 0.0 0.01 15.4 0.0 2.8 3 0 0 3 3 3 2 HAD-hyrolase-like Hydrolase_6 PF13344.1 CEH19416.1 - 6.4e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PH_10 PF15411.1 CEH19417.1 - 1.9e-26 92.5 0.0 3.5e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 CEH19417.1 - 5.9e-05 22.8 0.9 0.00011 21.9 0.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CEH19417.1 - 0.0078 15.9 0.3 0.02 14.5 0.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CEH19417.1 - 0.012 15.2 0.1 0.026 14.1 0.1 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) VWA_3 PF13768.1 CEH19417.1 - 0.022 14.4 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain zf-C3HC4_2 PF13923.1 CEH19417.1 - 0.3 11.1 0.8 0.62 10.1 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CEH19417.1 - 0.66 9.6 0.3 1.4 8.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 4HBT PF03061.17 CEH19420.1 - 6.6e-11 42.1 0.2 1.1e-10 41.4 0.2 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 CEH19420.1 - 0.00032 20.6 0.0 0.00041 20.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) HLH PF00010.21 CEH19421.1 - 1.6e-15 56.5 0.2 4.3e-15 55.1 0.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nop14 PF04147.7 CEH19421.1 - 0.25 9.1 2.6 0.39 8.5 1.8 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 CEH19421.1 - 2.1 7.9 6.2 0.68 9.5 1.9 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 CEH19421.1 - 3.1 5.6 7.1 0.4 8.6 0.0 2.2 2 0 0 2 2 2 0 CDC45-like protein PHY PF00360.15 CEH19422.1 - 3.7e-25 88.1 0.0 1.3e-24 86.3 0.0 1.9 2 0 0 2 2 2 1 Phytochrome region HATPase_c PF02518.21 CEH19422.1 - 8.6e-20 70.5 1.8 3.1e-18 65.5 1.2 2.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CEH19422.1 - 3.1e-17 62.5 0.0 1.4e-16 60.4 0.0 2.1 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 CEH19422.1 - 1.3e-15 57.8 0.1 1.6e-14 54.2 0.0 2.8 3 0 0 3 3 3 1 GAF domain HisKA PF00512.20 CEH19422.1 - 1.3e-11 44.3 0.9 4e-11 42.7 0.6 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 CEH19422.1 - 2.4e-11 44.0 0.0 1.1e-10 41.9 0.0 2.1 2 0 0 2 2 2 1 PAS fold Endosulfine PF04667.12 CEH19423.1 - 6.5e-20 70.8 0.0 9.4e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Shugoshin_C PF07557.6 CEH19424.1 - 0.21 11.0 1.6 0.39 10.2 1.1 1.5 1 0 0 1 1 1 0 Shugoshin C terminus Acyl-CoA_dh_1 PF00441.19 CEH19425.1 - 1.3e-29 103.2 0.7 2.2e-29 102.5 0.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CEH19425.1 - 3.1e-17 61.8 0.3 9.1e-17 60.3 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 CEH19425.1 - 1.3e-15 56.9 0.0 2.6e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 CEH19425.1 - 6.4e-10 39.6 0.1 6.5e-09 36.3 0.0 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CEH19425.1 - 2.4e-05 24.6 0.1 4.3e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain COesterase PF00135.23 CEH19426.1 - 1.4e-68 231.9 0.0 3.6e-58 197.6 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CEH19426.1 - 9.9e-05 22.0 0.2 0.016 14.7 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CEH19426.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family SecE PF00584.15 CEH19427.1 - 1e-12 47.3 0.0 1.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF2976 PF11190.3 CEH19427.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Nucleos_tra2_C PF07662.8 CEH19428.1 - 1.6e-60 204.1 2.0 3.1e-60 203.2 1.4 1.5 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 CEH19428.1 - 1.3e-11 44.6 4.7 1.3e-11 44.6 3.2 3.6 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Rpr2 PF04032.11 CEH19429.1 - 7.5e-13 48.1 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_clus PF00172.13 CEH19432.1 - 1.6e-10 40.7 6.1 2.5e-10 40.0 4.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP1_N PF06424.7 CEH19433.1 - 0.52 10.6 8.2 2 8.7 5.7 1.8 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Inhibitor_I9 PF05922.11 CEH19434.1 - 1.7e-05 25.3 0.0 5.6e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 zf-CDGSH PF09360.5 CEH19435.1 - 0.029 14.2 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type L51_S25_CI-B8 PF05047.11 CEH19437.1 - 5.3e-05 22.8 0.1 6.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Tcp11 PF05794.8 CEH19438.1 - 4e-64 216.9 0.0 5.5e-47 160.4 0.0 3.6 2 1 1 3 3 3 3 T-complex protein 11 LIM PF00412.17 CEH19439.1 - 1e-15 57.5 31.8 1e-07 31.9 5.1 4.2 4 0 0 4 4 4 3 LIM domain Med27 PF11571.3 CEH19439.1 - 0.061 13.4 6.2 6.9 6.8 0.0 3.7 3 0 0 3 3 3 0 Mediator complex subunit 27 NAM-associated PF14303.1 CEH19440.1 - 0.067 13.5 19.4 0.083 13.2 13.4 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SR-25 PF10500.4 CEH19440.1 - 0.71 9.2 32.8 0.88 8.9 22.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1777 PF08648.7 CEH19440.1 - 1.1 9.0 50.5 1.3 8.6 35.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Cactin_mid PF10312.4 CEH19441.1 - 7.1e-64 214.6 5.9 1.2e-63 213.8 4.1 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 CEH19441.1 - 3.2e-53 178.5 5.6 5.3e-53 177.8 3.9 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein peroxidase PF00141.18 CEH19442.1 - 5.4e-49 166.7 0.0 8.5e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Fungal_lectin PF07938.7 CEH19442.1 - 0.0033 16.7 0.0 2.4 7.3 0.0 2.2 2 0 0 2 2 2 2 Fungal fucose-specific lectin RhoGEF PF00621.15 CEH19444.1 - 5.7e-42 143.6 0.1 1.2e-41 142.6 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 CEH19444.1 - 6.9e-39 132.6 0.0 1.8e-38 131.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 CEH19444.1 - 8.4e-28 96.2 0.0 1.5e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 CEH19444.1 - 8.6e-09 34.9 0.2 1.8e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 CEH19444.1 - 0.00013 22.0 0.1 0.00035 20.7 0.0 1.7 1 0 0 1 1 1 1 PH domain SNase PF00565.12 CEH19445.1 - 3.9e-22 78.5 2.6 1.3e-18 67.1 0.0 2.2 1 1 1 2 2 2 2 Staphylococcal nuclease homologue ThiS PF02597.15 CEH19446.1 - 0.042 14.2 0.2 0.073 13.5 0.1 1.4 1 0 0 1 1 1 0 ThiS family Spc7 PF08317.6 CEH19446.1 - 0.094 11.3 0.3 0.11 11.1 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein E1-E2_ATPase PF00122.15 CEH19447.1 - 3.7e-45 153.7 1.8 8.4e-45 152.5 1.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CEH19447.1 - 8.2e-43 147.3 0.9 1.5e-42 146.4 0.6 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CEH19447.1 - 1.1e-24 86.3 0.1 4.5e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 CEH19447.1 - 4.8e-14 52.9 0.0 1.2e-13 51.6 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEH19447.1 - 0.0048 16.5 0.8 0.015 14.8 0.3 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase zinc_ribbon_6 PF14599.1 CEH19447.1 - 0.15 11.8 0.5 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 Zinc-ribbon HTH_AsnC-type PF13404.1 CEH19447.1 - 0.3 10.6 4.8 0.31 10.6 0.0 3.3 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain Pro_isomerase PF00160.16 CEH19448.1 - 2e-47 161.2 0.1 4.6e-47 160.1 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CEH19448.1 - 8.6e-12 44.4 0.8 6.9e-06 25.7 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 CEH19448.1 - 0.075 12.8 0.6 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Mito_carr PF00153.22 CEH19450.1 - 2.5e-76 251.4 5.5 9.2e-23 79.7 0.0 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein tRNA_Me_trans PF03054.11 CEH19451.1 - 4.2e-91 305.1 0.0 2.2e-57 194.2 0.0 3.0 1 1 0 2 2 2 2 tRNA methyl transferase ThiI PF02568.9 CEH19451.1 - 0.0098 15.3 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.12 CEH19451.1 - 0.062 12.1 0.3 0.75 8.6 0.1 2.1 2 0 0 2 2 2 0 NAD synthase CBM_21 PF03370.8 CEH19452.1 - 1.1e-30 105.8 0.1 1.8e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit GSHPx PF00255.14 CEH19454.1 - 7.3e-41 137.9 0.2 9.2e-41 137.5 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 CEH19454.1 - 4e-06 26.4 0.1 6e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CEH19454.1 - 5.9e-05 22.7 0.2 0.00013 21.6 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family SCO1-SenC PF02630.9 CEH19454.1 - 0.0023 17.5 0.1 0.0057 16.2 0.1 1.6 1 1 0 1 1 1 1 SCO1/SenC DUF4174 PF13778.1 CEH19454.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) RNA12 PF10443.4 CEH19455.1 - 4.5e-125 417.5 0.0 5.5e-125 417.2 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 CEH19455.1 - 5.7e-06 26.2 0.0 0.0028 17.4 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase Fasciclin PF02469.17 CEH19456.1 - 6.7e-57 191.0 0.0 1.7e-17 63.6 0.0 7.7 6 2 0 6 6 6 6 Fasciclin domain Herpes_US9 PF06072.6 CEH19456.1 - 0.22 11.3 2.3 3.6 7.4 0.7 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Disulph_isomer PF06491.6 CEH19456.1 - 0.23 11.3 0.2 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 Disulphide isomerase SIP1 PF04938.7 CEH19457.1 - 9.9e-16 57.7 0.3 8.5e-15 54.7 0.2 2.4 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) zf-C3HC4 PF00097.20 CEH19458.1 - 1.1e-10 40.9 8.2 2.1e-10 40.1 2.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CEH19458.1 - 2.6e-09 36.6 5.4 2.1e-08 33.7 2.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH19458.1 - 7.1e-09 35.5 8.2 1.1e-08 34.9 3.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CEH19458.1 - 1e-08 34.8 5.3 1e-08 34.8 3.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CEH19458.1 - 6e-08 32.3 10.2 1.5e-07 31.0 3.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CEH19458.1 - 1.6e-07 30.8 10.6 2e-07 30.5 4.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 CEH19458.1 - 3.6e-07 29.8 1.8 3.6e-07 29.8 1.3 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CEH19458.1 - 0.00015 21.3 7.3 0.00021 20.9 2.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zinc_ribbon_5 PF13719.1 CEH19458.1 - 0.016 14.7 5.4 1 8.9 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-Nse PF11789.3 CEH19458.1 - 0.029 13.8 0.9 0.029 13.8 0.6 2.3 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 CEH19458.1 - 0.034 13.7 9.2 0.057 13.0 4.2 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CEH19458.1 - 0.037 14.1 2.5 1.1 9.4 0.9 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger zf-Apc11 PF12861.2 CEH19458.1 - 0.04 13.7 1.6 0.43 10.4 0.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 CEH19458.1 - 0.058 13.3 0.0 0.23 11.4 0.0 2.1 1 0 0 1 1 1 0 U-box domain zf-Di19 PF05605.7 CEH19458.1 - 0.073 13.2 0.8 0.66 10.1 0.1 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.1 CEH19458.1 - 0.092 12.4 6.4 1.6 8.5 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain SAP PF02037.22 CEH19458.1 - 0.13 11.8 0.2 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 SAP domain FYVE PF01363.16 CEH19458.1 - 0.43 10.5 9.7 19 5.2 4.9 2.7 2 1 0 2 2 2 0 FYVE zinc finger zf-MIZ PF02891.15 CEH19458.1 - 1.8 8.1 5.0 4.2 6.9 1.4 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF2946 PF11162.3 CEH19458.1 - 1.9 8.7 13.3 0.033 14.3 1.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2946) Mago-bind PF09282.5 CEH19459.1 - 6.8e-12 44.7 1.0 2e-11 43.2 0.7 1.9 1 0 0 1 1 1 1 Mago binding Macoilin PF09726.4 CEH19459.1 - 2.3 6.3 9.9 2.7 6.1 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein MFS_1 PF07690.11 CEH19460.1 - 1.8e-34 119.0 18.8 1.8e-34 119.0 13.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH19460.1 - 1.3e-14 53.6 1.9 1.3e-14 53.6 1.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CEH19460.1 - 1e-07 30.5 0.3 1.6e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pex2_Pex12 PF04757.9 CEH19461.1 - 5.5e-47 160.1 2.4 6.8e-47 159.8 1.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 CEH19461.1 - 5.6e-05 22.7 3.2 8.7e-05 22.1 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CEH19461.1 - 0.00029 20.7 5.1 0.00051 20.0 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CEH19461.1 - 0.014 15.2 5.2 0.025 14.3 3.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 CEH19461.1 - 1.2 8.8 3.7 1.9 8.1 2.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CDRN PF05174.7 CEH19461.1 - 5.6 6.4 8.6 3.1 7.3 0.1 3.9 4 1 1 5 5 5 0 Cysteine-rich D. radiodurans N terminus Peptidase_M22 PF00814.20 CEH19462.1 - 4e-50 170.7 0.5 6.1e-16 58.7 0.7 4.1 3 1 1 4 4 4 4 Glycoprotease family Senescence PF06911.7 CEH19463.1 - 6.9e-33 113.8 2.2 2.4e-32 112.0 1.5 1.8 1 1 0 1 1 1 1 Senescence-associated protein DIOX_N PF14226.1 CEH19464.1 - 1.1e-24 87.1 0.0 1.6e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CEH19464.1 - 1e-14 54.5 0.0 2.5e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SUR7 PF06687.7 CEH19465.1 - 4.7e-24 85.1 3.6 5.8e-24 84.8 2.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family MFS_1 PF07690.11 CEH19466.1 - 9.9e-25 86.9 35.9 1.1e-19 70.4 12.1 3.1 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH19466.1 - 1.5e-06 27.1 2.0 1.5e-06 27.1 1.4 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter MARVEL PF01284.18 CEH19466.1 - 0.074 12.8 19.4 0.85 9.4 0.0 3.9 3 1 0 3 3 3 0 Membrane-associating domain ADH_zinc_N PF00107.21 CEH19467.1 - 3.1e-20 72.0 0.4 5.3e-20 71.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CEH19467.1 - 7.5e-09 36.5 0.3 2e-08 35.1 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CEH19467.1 - 0.0008 19.1 0.0 0.0025 17.5 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 CEH19467.1 - 0.0025 17.7 0.9 0.0025 17.7 0.6 1.6 2 0 0 2 2 2 1 short chain dehydrogenase ACP_syn_III_C PF08541.5 CEH19467.1 - 0.067 13.2 0.5 0.26 11.3 0.2 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal LRR_6 PF13516.1 CEH19468.1 - 1.2e-08 34.1 10.9 4.2 7.7 0.1 7.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 CEH19468.1 - 2.8e-07 29.9 2.9 1.3 8.7 0.1 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CEH19468.1 - 0.0041 16.8 9.6 4.8 7.0 0.2 4.0 3 1 0 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 CEH19468.1 - 0.13 12.5 4.4 4.5e+02 1.8 0.0 5.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 CEH19468.1 - 0.22 11.6 3.2 1.4e+02 3.1 0.0 5.4 6 1 1 7 7 7 0 Leucine Rich Repeat eIF3g PF12353.3 CEH19469.1 - 9.1e-43 145.2 3.0 1.4e-42 144.6 2.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CEH19469.1 - 2.4e-20 71.9 0.0 4.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CEH19469.1 - 3.1e-17 62.3 0.0 5.5e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH19469.1 - 4.8e-10 39.1 0.0 8.8e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CEH19469.1 - 0.0014 18.4 1.2 0.092 12.5 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif GLTP PF08718.6 CEH19470.1 - 3.1e-42 144.1 0.0 4.4e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) LrgB PF04172.11 CEH19472.1 - 4.5e-28 97.8 8.5 1.5e-27 96.2 5.5 2.2 1 1 1 2 2 2 1 LrgB-like family CcmD PF04995.9 CEH19472.1 - 0.0087 15.7 0.1 0.048 13.4 0.0 2.4 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) FAM70 PF14967.1 CEH19472.1 - 4.9 6.2 8.1 0.086 12.0 0.1 1.9 2 0 0 2 2 2 0 FAM70 protein muHD PF10291.4 CEH19473.1 - 1.5e-54 184.8 0.0 2.2e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 CEH19473.1 - 1.7e-07 31.3 0.0 6.6e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF3347 PF11827.3 CEH19473.1 - 0.25 11.3 5.3 0.46 10.4 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Cutinase PF01083.17 CEH19474.1 - 2.4e-30 105.5 0.4 4e-30 104.8 0.2 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 CEH19474.1 - 0.0032 17.0 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CEH19474.1 - 0.017 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PEPCK_ATP PF01293.15 CEH19476.1 - 3.5e-217 721.4 0.0 4.3e-217 721.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 CEH19476.1 - 0.0074 15.7 0.0 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 CEH19476.1 - 0.0087 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CEH19476.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 CEH19476.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CEH19478.1 - 3.3e-41 140.5 0.0 7.5e-41 139.4 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CEH19478.1 - 1.6e-05 25.0 0.0 0.0023 18.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 CEH19478.1 - 2.5e-05 24.0 0.0 0.00011 21.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CEH19478.1 - 0.00019 21.3 0.0 0.00057 19.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CEH19478.1 - 0.00077 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CEH19478.1 - 0.0011 18.9 0.0 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CEH19478.1 - 0.0031 18.3 0.1 0.0077 17.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CEH19478.1 - 0.0085 16.0 0.0 0.02 14.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CEH19478.1 - 0.0098 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CEH19478.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 CEH19478.1 - 0.011 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CEH19478.1 - 0.015 15.0 0.1 0.015 15.0 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain Sigma54_activ_2 PF14532.1 CEH19478.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 CEH19478.1 - 0.024 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 CEH19478.1 - 0.05 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CEH19478.1 - 0.051 13.8 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CEH19478.1 - 0.054 13.3 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CEH19478.1 - 0.065 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 CEH19478.1 - 0.065 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 CEH19478.1 - 0.065 12.9 0.2 16 5.0 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase RNA_helicase PF00910.17 CEH19478.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 CEH19478.1 - 0.13 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Exo_endo_phos_2 PF14529.1 CEH19479.1 - 8.5e-11 41.5 0.1 3.7e-10 39.4 0.0 2.2 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CEH19479.1 - 2.7e-09 37.3 0.9 2.7e-09 37.3 0.6 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 CEH19479.1 - 2.1e-06 27.5 12.9 3.6e-06 26.8 6.4 2.7 2 1 0 2 2 2 1 GRF zinc finger F-box PF00646.28 CEH19480.1 - 1.2e-06 27.9 0.4 2.4e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CEH19480.1 - 1.6e-06 27.7 0.9 3.6e-06 26.5 0.6 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 CEH19480.1 - 4.2e-05 23.2 1.5 3.8 7.5 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.1 CEH19480.1 - 0.036 14.3 0.2 1.5 9.1 0.0 3.3 1 1 1 2 2 2 0 PQQ-like domain PQQ PF01011.16 CEH19480.1 - 0.6 9.7 2.7 3.3 7.4 0.1 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat SH3_9 PF14604.1 CEH19481.1 - 1.2e-09 37.6 0.0 2.2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEH19481.1 - 2.5e-07 29.9 0.0 4.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.6 CEH19481.1 - 0.011 15.2 0.3 0.011 15.2 0.2 1.8 2 0 0 2 2 2 0 Podoplanin RNA_pol_Rpb1_2 PF00623.15 CEH19484.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Zds_C PF08632.5 CEH19485.1 - 0.021 14.2 0.3 0.042 13.2 0.0 1.6 2 0 0 2 2 2 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term OSTbeta PF15048.1 CEH19485.1 - 0.14 12.2 0.2 0.18 11.9 0.2 1.3 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein RasGEF PF00617.14 CEH19486.1 - 5.2e-49 166.5 0.0 8.7e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CEH19486.1 - 7.9e-21 74.1 0.1 1.5e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 CEH19486.1 - 2.2e-13 49.5 0.0 4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CEH19486.1 - 7.3e-13 47.6 0.0 1.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CEH19486.1 - 2.7e-12 45.9 0.0 4.9e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain IKI3 PF04762.7 CEH19486.1 - 0.054 11.3 0.0 0.084 10.6 0.0 1.1 1 0 0 1 1 1 0 IKI3 family GTP1_OBG PF01018.17 CEH19489.1 - 1.7e-31 108.9 3.7 1.1e-23 83.6 2.1 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 CEH19489.1 - 5.4e-18 65.0 0.0 1.5e-17 63.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CEH19489.1 - 3.3e-05 23.3 0.0 0.014 14.8 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CEH19489.1 - 6.2e-05 22.8 0.0 0.1 12.4 0.0 3.1 3 0 0 3 3 3 2 Dynamin family FeoB_N PF02421.13 CEH19489.1 - 0.00021 20.6 0.0 0.025 13.8 0.0 3.0 3 0 0 3 3 3 1 Ferrous iron transport protein B Arf PF00025.16 CEH19489.1 - 0.0017 17.6 0.0 1.4 8.1 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family ABC_tran PF00005.22 CEH19489.1 - 0.015 15.6 0.3 0.047 13.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter cobW PF02492.14 CEH19489.1 - 0.029 13.8 0.0 7.3 5.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CEH19489.1 - 0.087 11.5 0.1 0.4 9.4 0.0 2.0 3 0 0 3 3 3 0 ArgK protein NOG1 PF06858.9 CEH19489.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) SUI1 PF01253.17 CEH19490.1 - 1.6e-14 53.4 0.0 7.4e-14 51.3 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor SUI1 SWIB PF02201.13 CEH19490.1 - 0.0033 17.0 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain CLTH PF10607.4 CEH19492.1 - 2.9e-18 65.9 0.0 5e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40 PF00400.27 CEH19493.1 - 9.7e-46 152.0 10.0 7.6e-11 41.4 0.0 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 CEH19493.1 - 0.00035 20.1 0.0 0.043 13.2 0.0 2.9 2 1 1 3 3 3 1 PQQ-like domain Nup160 PF11715.3 CEH19493.1 - 0.0017 16.6 0.2 0.024 12.7 0.0 2.3 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CEH19493.1 - 0.0034 15.7 0.0 0.19 9.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 CEH19493.1 - 0.34 10.2 4.5 2.3 7.6 0.1 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature DUF883 PF05957.8 CEH19494.1 - 0.032 14.6 1.4 0.092 13.1 1.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RFX5_DNA_bdg PF14621.1 CEH19494.1 - 0.22 11.0 6.9 0.33 10.5 4.8 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain Herpes_LMP1 PF05297.6 CEH19494.1 - 5.8 5.7 6.3 1.8 7.4 1.3 1.9 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) RNase_T PF00929.19 CEH19496.1 - 1.7e-09 38.1 0.0 1.1e-06 29.0 0.0 2.6 3 0 0 3 3 3 2 Exonuclease SAP PF02037.22 CEH19496.1 - 2.2e-08 33.3 0.7 5.5e-08 32.1 0.2 1.9 2 0 0 2 2 2 1 SAP domain Semialdhyde_dhC PF02774.13 CEH19497.1 - 1.9e-38 132.1 0.2 4.5e-38 130.9 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 CEH19497.1 - 6.2e-28 97.5 0.0 1.2e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CEH19497.1 - 0.023 14.6 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.15 CEH19497.1 - 0.093 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.11 CEH19497.1 - 0.12 12.9 0.3 0.75 10.3 0.0 2.5 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase MbtH PF03621.8 CEH19498.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 MbtH-like protein UCH PF00443.24 CEH19499.1 - 4.7e-46 157.0 0.0 6.1e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CEH19499.1 - 3e-23 82.7 0.0 1.8e-22 80.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CEH19499.1 - 2.2e-07 30.1 0.0 5.3e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Med8 PF10232.4 CEH19499.1 - 0.028 13.9 0.2 0.057 12.9 0.1 1.5 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Ubiquitin_2 PF14560.1 CEH19499.1 - 0.047 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain YL1 PF05764.8 CEH19500.1 - 7.7e-37 127.1 15.7 7.7e-37 127.1 10.9 1.7 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 CEH19500.1 - 4.6e-11 42.0 0.4 7.5e-11 41.3 0.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain MFS_1 PF07690.11 CEH19501.1 - 9.2e-38 129.8 66.0 9e-34 116.7 30.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CEH19501.1 - 4.6e-09 35.3 7.3 4.6e-09 35.3 5.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter A_deaminase PF00962.17 CEH19502.1 - 1.1e-106 356.5 0.1 1.4e-106 356.1 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Methyltransf_16 PF10294.4 CEH19503.1 - 3e-17 62.6 0.0 6.5e-16 58.2 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CEH19503.1 - 0.0003 21.3 0.2 0.0015 19.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CEH19503.1 - 0.017 15.1 0.1 0.058 13.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CEH19503.1 - 0.02 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF4066 PF13278.1 CEH19503.1 - 0.023 13.9 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase Methyltransf_12 PF08242.7 CEH19503.1 - 0.066 13.6 0.0 0.31 11.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CEH19503.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain E1-E2_ATPase PF00122.15 CEH19504.1 - 2.7e-67 226.1 7.0 5.8e-66 221.8 3.6 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CEH19504.1 - 8.8e-43 145.9 1.4 8.8e-43 145.9 0.9 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CEH19504.1 - 6.8e-33 114.8 0.0 3.8e-32 112.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CEH19504.1 - 2.6e-22 78.0 0.1 6.9e-22 76.6 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CEH19504.1 - 9.9e-18 63.8 0.0 2e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CEH19504.1 - 8.1e-15 55.4 0.0 3.6e-14 53.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CEH19504.1 - 0.00018 21.1 2.0 0.0011 18.6 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CEH19504.1 - 0.034 14.3 0.0 0.096 12.8 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Galactosyl_T PF01762.16 CEH19505.1 - 4.1e-08 33.0 0.3 2.9e-05 23.7 0.0 2.9 2 1 1 3 3 3 2 Galactosyltransferase ECR1_N PF14382.1 CEH19506.1 - 2.1e-06 26.8 0.2 5e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Arrestin_C PF02752.17 CEH19508.1 - 1.5e-17 63.9 0.0 3.3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CEH19508.1 - 0.0082 15.9 0.0 7 6.4 0.0 2.8 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain FUSC PF04632.7 CEH19509.1 - 3.6 5.9 9.5 4.6 5.5 0.7 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Peptidase_M24 PF00557.19 CEH19510.1 - 7.5e-36 123.6 0.0 1.3e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CEH19510.1 - 2.7e-20 73.2 0.0 7.8e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain ATP-synt_ab PF00006.20 CEH19511.1 - 1.1e-109 365.0 0.0 1.5e-109 364.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CEH19511.1 - 7.8e-19 68.2 0.1 1.5e-18 67.2 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CEH19511.1 - 1.5e-14 53.9 4.1 2.7e-14 53.1 2.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain zf-HIT PF04438.11 CEH19512.1 - 2e-09 36.9 10.4 3.2e-09 36.2 7.2 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF3926 PF13080.1 CEH19512.1 - 0.31 10.6 1.6 6.8 6.3 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) TP_methylase PF00590.15 CEH19513.1 - 1.1e-16 61.1 0.2 5e-16 59.0 0.1 2.0 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases HypD PF01924.11 CEH19513.1 - 0.12 11.0 0.0 0.3 9.7 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase formation hypA family Abhydrolase_6 PF12697.2 CEH19514.1 - 8.1e-33 114.2 0.7 8.1e-33 114.2 0.5 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH19514.1 - 4.6e-16 59.0 0.3 9.5e-15 54.7 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CEH19514.1 - 7.8e-14 51.6 0.2 1.5e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family CMD PF02627.15 CEH19514.1 - 2.8e-08 33.4 0.4 2e-07 30.7 0.0 2.6 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Hydrolase_4 PF12146.3 CEH19514.1 - 1.9e-05 24.4 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CEH19514.1 - 0.00059 19.1 0.5 0.29 10.3 0.0 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CEH19514.1 - 0.00081 18.8 0.0 0.023 14.1 0.0 2.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 CEH19514.1 - 0.012 15.0 0.3 0.028 13.8 0.2 1.7 1 1 0 1 1 1 0 Putative esterase Thioesterase PF00975.15 CEH19514.1 - 0.029 14.5 0.3 0.12 12.5 0.0 2.0 2 1 0 2 2 2 0 Thioesterase domain BAAT_C PF08840.6 CEH19514.1 - 0.036 13.7 0.1 0.18 11.4 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2236 PF09995.4 CEH19515.1 - 2.3e-15 56.5 0.3 8e-15 54.7 0.2 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) PdxA PF04166.7 CEH19515.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA Mito_carr PF00153.22 CEH19516.1 - 5.2e-39 131.8 9.9 2.3e-16 59.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF607 PF04678.8 CEH19517.1 - 3.3e-38 131.3 0.5 3.3e-38 131.3 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF607 DUF1281 PF06924.6 CEH19517.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF3323 PF11796.3 CEH19517.1 - 0.056 12.7 2.5 0.14 11.4 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) UQ_con PF00179.21 CEH19519.1 - 8.2e-21 73.8 0.0 1.5e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 CEH19519.1 - 0.0012 18.6 2.1 0.0012 18.6 1.5 2.2 2 0 0 2 2 2 1 UBA/TS-N domain UEV PF05743.8 CEH19519.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain IBR PF01485.16 CEH19519.1 - 0.64 9.9 5.2 1.8 8.5 3.6 1.8 1 1 0 1 1 1 0 IBR domain Glyco_hydro_cc PF11790.3 CEH19521.1 - 7.8e-31 107.3 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF1005 PF06219.7 CEH19522.1 - 0.068 11.8 0.1 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) GvpL_GvpF PF06386.6 CEH19522.1 - 0.13 11.8 3.5 0.18 11.3 0.0 2.5 3 0 0 3 3 3 0 Gas vesicle synthesis protein GvpL/GvpF zf-RanBP PF00641.13 CEH19523.1 - 3.2e-06 26.1 13.8 0.0044 16.0 1.1 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 CEH19523.1 - 0.29 10.9 4.9 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Double zinc ribbon Thioredoxin PF00085.15 CEH19524.1 - 3.2e-59 197.0 3.3 4.3e-28 97.0 0.1 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CEH19524.1 - 8e-42 143.1 1.9 8.5e-34 116.9 0.1 3.8 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CEH19524.1 - 1.2e-11 44.5 0.2 0.00066 19.7 0.0 3.8 3 1 0 3 3 3 3 Thioredoxin-like Thioredoxin_7 PF13899.1 CEH19524.1 - 1.4e-10 41.0 0.4 0.00013 21.8 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CEH19524.1 - 3.9e-09 36.6 1.9 0.0013 18.8 0.1 3.6 3 2 0 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.12 CEH19524.1 - 3.1e-05 22.9 3.1 5.2e-05 22.1 2.1 1.3 1 0 0 1 1 1 1 Calsequestrin Redoxin PF08534.5 CEH19524.1 - 0.00013 21.5 1.8 0.0074 15.8 0.0 3.0 3 0 0 3 3 3 1 Redoxin AhpC-TSA PF00578.16 CEH19524.1 - 0.00087 18.9 1.1 0.15 11.7 0.0 3.2 2 1 1 3 3 3 1 AhpC/TSA family Thioredoxin_4 PF13462.1 CEH19524.1 - 0.0081 16.1 0.4 2.3 8.2 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin Nup35_RRM_2 PF14605.1 CEH19525.1 - 5.4e-10 38.8 0.0 0.00055 19.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 CEH19525.1 - 5.3e-09 35.9 0.0 6.1e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CEH19525.1 - 1.1e-08 34.8 0.1 8.1e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CEH19525.1 - 5.6e-07 29.1 0.0 6.7e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CEH19525.1 - 7.6e-07 28.6 4.3 1.5e-06 27.7 3.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 CEH19525.1 - 2.6e-06 27.4 0.0 4e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 PWI domain RRM_3 PF08777.6 CEH19525.1 - 0.031 14.1 0.0 0.89 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif LCAT PF02450.10 CEH19526.1 - 3.6e-09 36.0 0.0 7.4e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CEH19526.1 - 8.5e-07 29.0 0.1 3.1e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CEH19526.1 - 1.5e-05 24.6 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 CEH19526.1 - 0.0004 19.9 0.0 0.00081 19.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 CEH19526.1 - 0.003 17.0 0.2 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 Putative esterase DUF900 PF05990.7 CEH19526.1 - 0.0043 16.4 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 CEH19526.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CEH19526.1 - 0.031 13.8 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase DUF676 PF05057.9 CEH19526.1 - 0.087 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF1134 PF06577.7 CEH19526.1 - 0.23 10.9 0.0 0.43 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) Nucleo_P87 PF07267.6 CEH19526.1 - 4.2 5.9 7.7 8.6 4.9 5.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Herpes_gE PF02480.11 CEH19527.1 - 0.0082 14.4 1.2 0.017 13.4 0.8 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CEH19527.1 - 0.063 13.6 0.8 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3481 PF11980.3 CEH19527.1 - 0.093 12.5 0.2 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) DUF2029 PF09594.5 CEH19527.1 - 0.12 11.8 2.1 0.2 11.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) IncA PF04156.9 CEH19527.1 - 0.15 11.6 0.6 0.23 11.0 0.4 1.2 1 0 0 1 1 1 0 IncA protein DUF3609 PF12259.3 CEH19527.1 - 0.16 10.5 0.1 0.24 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) CD34_antigen PF06365.7 CEH19527.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family SKG6 PF08693.5 CEH19527.1 - 2.2 7.6 9.8 4.7 6.5 6.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.1 CEH19527.1 - 3.8 7.6 0.0 3.8 7.6 0.0 3.5 2 1 0 3 3 3 0 Wnt and FGF inhibitory regulator DEAD PF00270.24 CEH19528.1 - 1.7e-34 118.7 0.0 7.7e-33 113.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH19528.1 - 2.9e-16 59.0 0.0 3.7e-15 55.5 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CEH19528.1 - 0.037 12.8 0.0 0.062 12.0 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 CEH19528.1 - 0.075 12.8 0.1 0.32 10.7 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DAHP_synth_2 PF01474.11 CEH19529.1 - 1.1e-174 580.9 0.0 1.3e-174 580.6 0.0 1.1 1 0 0 1 1 1 1 Class-II DAHP synthetase family MIP PF00230.15 CEH19530.1 - 1.6e-42 145.5 8.1 2e-42 145.2 5.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein Med12 PF09497.5 CEH19533.1 - 4.7e-22 77.7 0.0 1.1e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 EMP70 PF02990.11 CEH19534.1 - 8.1e-176 585.5 0.0 9.7e-176 585.2 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3154 PF11351.3 CEH19534.1 - 0.21 11.3 0.1 0.21 11.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) ApbA_C PF08546.6 CEH19536.1 - 4.3e-21 75.1 0.0 6.7e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CEH19536.1 - 3.1e-20 72.1 0.0 4.4e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.16 CEH19536.1 - 0.037 13.5 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 CEH19536.1 - 0.043 12.9 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain E3_binding PF02817.12 CEH19536.1 - 0.1 12.2 2.0 2.7 7.6 0.2 3.6 5 0 0 5 5 5 0 e3 binding domain COX5A PF02284.11 CEH19537.1 - 7.3e-41 138.5 0.1 9.5e-41 138.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va NTase_sub_bind PF08780.6 CEH19537.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like V_ATPase_I PF01496.14 CEH19538.1 - 3.8e-277 921.1 0.0 4.3e-277 920.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Med9 PF07544.8 CEH19538.1 - 0.1 12.3 1.3 6.4 6.5 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Amino_oxidase PF01593.19 CEH19540.1 - 1.2e-27 97.0 0.1 6.4e-19 68.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CEH19540.1 - 1.3e-05 25.0 0.0 3.5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CEH19540.1 - 0.00019 21.5 0.3 0.00053 20.1 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CEH19540.1 - 0.014 14.4 0.3 0.023 13.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.11 CEH19543.1 - 2.9e-31 108.4 36.4 4e-31 108.0 25.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cytochrom_B561 PF03188.11 CEH19543.1 - 2.5 7.9 8.3 0.8 9.5 0.1 3.1 3 0 0 3 3 3 0 Eukaryotic cytochrome b561 PAF-AH_p_II PF03403.8 CEH19544.1 - 1.5e-36 125.5 0.0 2.3e-17 62.3 0.0 4.3 4 1 0 4 4 4 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 CEH19544.1 - 3.9e-10 39.6 0.1 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CEH19544.1 - 0.00084 19.2 6.7 0.0011 18.8 1.8 3.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CEH19544.1 - 0.012 14.5 0.0 0.17 10.7 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 CEH19544.1 - 0.033 12.9 0.0 0.23 10.2 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase RuBisCO_large PF00016.15 CEH19544.1 - 0.08 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Ribosomal_S14 PF00253.16 CEH19544.1 - 0.098 12.0 0.1 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e Nop10p PF04135.7 CEH19545.1 - 6e-21 73.9 0.1 7.1e-21 73.6 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family MFS_1 PF07690.11 CEH19549.1 - 3.8e-29 101.5 38.9 1.4e-28 99.6 27.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Rad10 PF03834.9 CEH19551.1 - 6.3e-28 96.2 0.0 9.5e-28 95.7 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 CEH19551.1 - 7.8e-05 22.7 0.0 0.00037 20.6 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.2 CEH19551.1 - 0.0001 22.1 0.1 0.0024 17.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif UIM PF02809.15 CEH19551.1 - 0.0029 17.0 0.2 0.0029 17.0 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin interaction motif ER-remodelling PF14755.1 CEH19551.1 - 0.88 9.6 14.7 1.4 9.0 8.9 2.2 2 0 0 2 2 2 0 Intracellular membrane remodeller NCA2 PF08637.5 CEH19552.1 - 1.5e-79 266.9 0.3 2.9e-79 265.9 0.2 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 BCNT PF07572.7 CEH19553.1 - 3.2e-13 49.3 1.9 4.4e-13 48.9 0.1 2.1 2 1 0 2 2 2 1 Bucentaur or craniofacial development DUF4578 PF15147.1 CEH19553.1 - 3.8 7.8 6.9 9.4 6.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) IMS PF00817.15 CEH19554.1 - 1.1e-38 132.3 0.4 6e-38 129.9 0.0 2.3 2 1 1 3 3 3 1 impB/mucB/samB family IMS_C PF11799.3 CEH19554.1 - 8.2e-14 51.6 0.0 1.9e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 CEH19554.1 - 9.7e-13 47.9 5.2 0.00086 19.1 0.0 4.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4414) BRCT PF00533.21 CEH19554.1 - 0.0018 18.3 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CEH19554.1 - 0.026 14.3 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain IMS_HHH PF11798.3 CEH19554.1 - 0.2 11.7 0.0 0.51 10.4 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif 2Fe-2S_thioredx PF01257.14 CEH19555.1 - 4.4e-60 201.4 0.0 5.5e-60 201.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Homeobox PF00046.24 CEH19556.1 - 2.9e-14 52.4 1.8 6.6e-14 51.2 1.3 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CEH19556.1 - 0.00089 18.9 0.0 0.0024 17.5 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Prothymosin PF03247.9 CEH19556.1 - 0.56 10.3 18.2 1.2 9.3 2.5 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family ACPS PF01648.15 CEH19557.1 - 6.3e-15 54.9 0.2 8.7e-15 54.5 0.1 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_S9 PF00326.16 CEH19558.1 - 8.2e-34 116.6 0.0 1.3e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CEH19558.1 - 1.8e-09 37.4 0.2 1.8e-06 27.7 0.0 2.6 2 1 0 2 2 2 2 Alpha/beta hydrolase family PIG-H PF10181.4 CEH19558.1 - 5.3e-09 35.5 0.0 5.9e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DLH PF01738.13 CEH19558.1 - 1.7e-06 27.5 0.0 3.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 CEH19558.1 - 1.9e-05 24.6 0.8 0.00045 20.1 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CEH19558.1 - 0.0013 18.3 0.0 0.47 9.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.15 CEH19558.1 - 0.0076 15.7 0.1 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 CEH19558.1 - 0.0092 15.7 0.0 0.25 11.0 0.0 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 CEH19558.1 - 0.014 14.9 0.0 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold LIP PF03583.9 CEH19558.1 - 0.016 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_2 PF02230.11 CEH19558.1 - 0.036 13.4 0.0 3.8 6.8 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 CEH19558.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) TFIIA_gamma_N PF02268.11 CEH19559.1 - 8.5e-27 92.5 0.2 1.2e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 CEH19559.1 - 1e-20 73.2 0.1 1.4e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Sporozoite_P67 PF05642.6 CEH19562.1 - 0.0015 16.5 0.1 0.0015 16.5 0.0 5.3 2 2 3 5 5 5 1 Sporozoite P67 surface antigen GPI-anchored PF10342.4 CEH19564.1 - 1.2e-11 44.9 3.6 2.6e-11 43.8 2.5 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PPTA PF01239.17 CEH19565.1 - 0.16 11.3 2.3 0.29 10.5 1.6 1.4 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat adh_short PF00106.20 CEH19566.1 - 2.4e-14 53.5 6.7 1.2e-06 28.5 0.6 2.9 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CEH19566.1 - 3.3e-06 26.9 2.4 0.00092 18.9 0.1 2.3 2 0 0 2 2 2 2 KR domain BatA PF07584.6 CEH19566.1 - 0.026 14.6 2.6 0.026 14.6 1.8 2.5 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal adh_short_C2 PF13561.1 CEH19566.1 - 0.042 13.6 0.3 0.56 9.9 0.3 2.1 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase BUD22 PF09073.5 CEH19568.1 - 2.6e-45 155.2 52.9 2.6e-45 155.2 36.7 3.6 2 1 0 2 2 2 1 BUD22 Ima1_N PF09779.4 CEH19569.1 - 4.2e-15 56.3 1.7 4.3e-12 46.6 0.1 2.5 2 0 0 2 2 2 2 Ima1 N-terminal domain Complex1_LYR_1 PF13232.1 CEH19570.1 - 1.5e-11 44.2 0.3 2.2e-11 43.7 0.2 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CEH19570.1 - 5.6e-08 32.4 5.1 9.5e-08 31.7 3.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ILVD_EDD PF00920.16 CEH19571.1 - 1.3e-195 650.7 0.2 1.5e-195 650.5 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family DAO PF01266.19 CEH19572.1 - 9.4e-50 169.4 0.4 1.5e-49 168.7 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.1 CEH19572.1 - 7.6e-08 32.3 0.1 1.9e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair FAD_oxidored PF12831.2 CEH19572.1 - 3.1e-06 26.5 0.8 5.7e-06 25.6 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CEH19572.1 - 7.6e-06 25.0 4.2 3.9e-05 22.6 2.9 2.2 1 1 0 1 1 1 1 FAD binding domain EF-hand_6 PF13405.1 CEH19572.1 - 7.6e-05 22.2 6.1 0.00038 20.0 0.0 3.0 3 0 0 3 3 2 1 EF-hand domain EF-hand_1 PF00036.27 CEH19572.1 - 9.3e-05 21.4 4.3 0.0078 15.4 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 CEH19572.1 - 0.001 18.6 0.1 0.001 18.6 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair FAD_binding_3 PF01494.14 CEH19572.1 - 0.0019 17.3 0.1 0.95 8.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 CEH19572.1 - 0.0045 16.8 1.2 0.02 14.7 0.8 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CEH19572.1 - 0.0049 16.8 0.6 0.032 14.2 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CEH19572.1 - 0.006 15.4 0.2 0.088 11.6 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A EF-hand_5 PF13202.1 CEH19572.1 - 0.013 14.7 0.1 0.013 14.7 0.1 2.2 2 0 0 2 2 2 0 EF hand 3HCDH_N PF02737.13 CEH19572.1 - 0.023 14.3 0.2 0.055 13.1 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dockerin_1 PF00404.13 CEH19572.1 - 0.064 12.9 0.9 0.26 11.0 0.6 2.1 1 0 0 1 1 1 0 Dockerin type I repeat HI0933_like PF03486.9 CEH19572.1 - 0.08 11.3 1.2 0.13 10.6 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 CEH19572.1 - 0.091 13.1 0.9 0.23 11.8 0.6 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CEH19572.1 - 0.41 9.5 2.2 0.99 8.2 1.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein zf-C2H2_2 PF12756.2 CEH19573.1 - 8.5e-32 109.2 0.6 2.8e-26 91.5 0.1 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CEH19573.1 - 2.2e-08 33.9 9.6 1.3e-07 31.5 2.2 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CEH19573.1 - 3.2e-05 23.9 6.4 0.00024 21.2 1.5 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CEH19573.1 - 0.019 15.2 10.9 0.049 13.9 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-DBF PF07535.7 CEH19573.1 - 0.22 11.2 3.4 0.19 11.4 0.2 2.4 3 0 0 3 3 3 0 DBF zinc finger GILT PF03227.11 CEH19574.1 - 5.6e-08 32.6 0.1 1e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) peroxidase PF00141.18 CEH19575.1 - 2.3e-48 164.6 0.0 3.3e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase MotB_plug PF13677.1 CEH19575.1 - 0.12 11.7 0.1 0.31 10.3 0.0 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Mito_carr PF00153.22 CEH19576.1 - 3.1e-56 187.0 3.1 3.2e-18 65.2 0.0 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein zf-DHHC PF01529.15 CEH19577.1 - 2.1e-43 147.6 0.2 4.9e-43 146.5 0.2 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase Evr1_Alr PF04777.8 CEH19578.1 - 5e-29 100.0 0.0 7.4e-29 99.5 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family FGGY_N PF00370.16 CEH19581.1 - 1.7e-65 220.7 0.2 2.3e-65 220.3 0.1 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CEH19581.1 - 7.2e-64 215.0 1.2 1.6e-63 213.9 0.8 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RNB PF00773.14 CEH19582.1 - 8.3e-69 232.3 2.8 2e-58 198.2 0.0 2.2 1 1 1 2 2 2 2 RNB domain PIN_4 PF13638.1 CEH19582.1 - 1.7e-09 37.8 0.0 7e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 PIN domain OB_RNB PF08206.6 CEH19582.1 - 0.083 12.4 1.1 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF4448 PF14610.1 CEH19583.1 - 0.051 13.0 1.6 0.23 10.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Macoilin PF09726.4 CEH19583.1 - 1.3 7.1 4.5 1.8 6.7 3.1 1.2 1 0 0 1 1 1 0 Transmembrane protein NIF PF03031.13 CEH19584.1 - 5.2e-50 169.2 0.0 7.1e-50 168.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CENP-B_dimeris PF09026.5 CEH19584.1 - 0.28 11.4 11.4 0.77 10.0 7.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Herpes_LMP2 PF07415.6 CEH19584.1 - 2.4 6.6 3.0 4.3 5.7 2.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Ribosomal_L14 PF00238.14 CEH19585.1 - 2.1e-43 146.9 1.3 2.4e-43 146.7 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PIN_4 PF13638.1 CEH19586.1 - 1.1e-19 70.8 0.0 1.9e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 PIN domain DEAD PF00270.24 CEH19587.1 - 1.7e-19 69.9 0.0 3.8e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CEH19587.1 - 8.4e-17 60.8 0.0 5.7e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CEH19587.1 - 7.9e-06 25.8 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 CEH19587.1 - 0.14 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_16 PF13191.1 CEH19588.1 - 3.7e-05 23.7 1.1 0.00027 20.9 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CEH19588.1 - 0.00048 19.5 0.1 0.0027 17.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CEH19588.1 - 0.00053 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 CEH19588.1 - 0.0024 17.3 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Asp_Glu_race PF01177.17 CEH19588.1 - 0.0053 16.6 0.0 0.033 14.1 0.0 2.2 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase AAA_22 PF13401.1 CEH19588.1 - 0.0065 16.6 0.1 0.032 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CEH19588.1 - 0.02 13.7 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DAP3 PF10236.4 CEH19588.1 - 0.093 11.6 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SCO1-SenC PF02630.9 CEH19589.1 - 2.2e-48 164.1 0.0 4e-48 163.2 0.0 1.4 1 1 0 1 1 1 1 SCO1/SenC CAP_GLY PF01302.20 CEH19589.1 - 3.2e-24 84.3 0.8 5.9e-24 83.5 0.6 1.5 1 0 0 1 1 1 1 CAP-Gly domain AhpC-TSA PF00578.16 CEH19589.1 - 0.019 14.6 0.0 0.075 12.7 0.0 1.9 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.1 CEH19589.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DUF4336 PF14234.1 CEH19590.1 - 8.5e-10 38.2 0.0 0.00015 21.0 0.0 3.0 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) Secretin_N PF03958.12 CEH19592.1 - 0.026 14.7 0.1 0.035 14.2 0.1 1.6 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain Mo-co_dimer PF03404.11 CEH19592.1 - 0.091 12.3 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain TFIIE_alpha PF02002.12 CEH19593.1 - 2.1e-14 52.8 0.0 5e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit zf-H2C2_2 PF13465.1 CEH19593.1 - 0.24 11.7 0.5 0.44 10.9 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger double domain TRAPP PF04051.11 CEH19594.1 - 1.3e-32 112.4 0.0 2.1e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component HrpB1_HrpK PF09613.5 CEH19594.1 - 0.099 12.1 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) SWIB PF02201.13 CEH19595.1 - 3.4e-15 55.4 0.0 5.5e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain COX7C PF02935.11 CEH19596.1 - 4.3e-12 45.6 0.4 5.2e-12 45.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Brix PF04427.13 CEH19597.1 - 1.7e-38 132.2 0.9 1.8e-38 132.1 0.0 1.5 2 0 0 2 2 2 1 Brix domain LAT PF15234.1 CEH19597.1 - 0.023 14.1 1.8 0.044 13.2 1.2 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Cas_Csy4 PF09618.5 CEH19597.1 - 0.24 11.1 3.4 0.5 10.1 2.4 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DUF221 PF02714.10 CEH19599.1 - 8.1e-46 156.3 22.0 1.2e-45 155.8 15.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CEH19599.1 - 3.7e-14 52.5 3.0 3.7e-14 52.5 2.0 3.0 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CEH19599.1 - 0.0022 18.4 4.6 0.0028 18.1 0.8 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 CEH19599.1 - 0.011 15.7 0.0 0.2 11.6 0.0 2.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4545 PF15078.1 CEH19599.1 - 0.025 13.5 0.1 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) UBA PF00627.26 CEH19602.1 - 0.0092 15.7 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Extensin_2 PF04554.8 CEH19603.1 - 0.11 12.3 5.3 0.14 11.9 1.0 2.2 2 0 0 2 2 2 0 Extensin-like region His_Phos_1 PF00300.17 CEH19605.1 - 3.8e-13 49.8 0.0 8.1e-13 48.7 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ADIP PF11559.3 CEH19605.1 - 0.062 13.1 1.5 0.097 12.5 1.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MerR-DNA-bind PF09278.6 CEH19605.1 - 0.11 12.8 3.5 0.1 12.9 1.2 1.8 1 1 1 2 2 2 0 MerR, DNA binding Spc7 PF08317.6 CEH19605.1 - 0.3 9.7 1.4 0.42 9.2 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HlyIII PF03006.15 CEH19607.1 - 5.9e-45 153.3 14.2 8e-45 152.9 9.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related Na_H_Exchanger PF00999.16 CEH19609.1 - 2e-45 154.9 43.2 1.8e-25 89.2 13.0 2.3 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Usp PF00582.21 CEH19609.1 - 0.017 15.2 0.6 0.062 13.4 0.4 2.0 1 0 0 1 1 1 0 Universal stress protein family PALP PF00291.20 CEH19610.1 - 1.2e-60 205.3 1.1 1.4e-37 129.6 0.1 2.0 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme CTP_transf_3 PF02348.14 CEH19610.1 - 0.027 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Titin_Z PF09042.6 CEH19610.1 - 3.7 7.2 6.3 0.76 9.4 0.6 2.2 2 0 0 2 2 2 0 Titin Z DUF3395 PF11875.3 CEH19611.1 - 1.2e-28 99.6 0.0 2.2e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 CEH19611.1 - 1e-17 63.5 0.1 1.9e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain ABC_membrane PF00664.18 CEH19612.1 - 1.2e-57 195.4 21.7 1.8e-29 103.0 5.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CEH19612.1 - 3.5e-51 173.0 0.1 1.5e-30 106.2 0.1 2.8 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 CEH19612.1 - 8.7e-09 35.6 4.0 0.00087 19.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CEH19612.1 - 3.2e-08 33.0 4.6 0.0014 17.9 1.2 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CEH19612.1 - 7.1e-08 32.7 0.0 0.087 12.7 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CEH19612.1 - 1.1e-06 28.0 0.3 0.046 13.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CEH19612.1 - 1.5e-06 28.1 0.4 0.036 14.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 CEH19612.1 - 2.5e-06 27.9 0.6 0.022 15.2 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 CEH19612.1 - 3.2e-06 27.9 0.1 0.02 15.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CEH19612.1 - 4.5e-06 26.3 0.6 0.029 13.8 0.0 2.8 3 0 0 3 3 2 2 AAA-like domain MobB PF03205.9 CEH19612.1 - 6.4e-06 25.9 0.2 0.019 14.6 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 CEH19612.1 - 6.8e-06 25.1 0.1 0.0013 17.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 CEH19612.1 - 2.4e-05 23.5 1.8 0.032 13.3 0.1 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_23 PF13476.1 CEH19612.1 - 3.7e-05 24.1 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 CEH19612.1 - 3.9e-05 23.5 0.7 0.054 13.3 0.1 2.6 2 0 0 2 2 2 2 Dynamin family DUF258 PF03193.11 CEH19612.1 - 7.2e-05 22.0 0.3 0.2 10.8 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CEH19612.1 - 9.8e-05 21.8 6.5 0.1 11.9 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 CEH19612.1 - 0.00026 21.2 0.0 0.25 11.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 CEH19612.1 - 0.0004 19.1 0.5 0.032 12.8 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 CEH19612.1 - 0.0006 19.2 6.0 0.073 12.5 0.0 3.0 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 CEH19612.1 - 0.0011 19.0 4.9 0.62 10.2 0.1 3.4 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CEH19612.1 - 0.0012 18.3 0.2 0.37 10.2 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 CEH19612.1 - 0.0017 17.9 0.3 0.85 9.1 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 CEH19612.1 - 0.002 17.6 0.0 2.2 7.7 0.0 2.4 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Adeno_IVa2 PF02456.10 CEH19612.1 - 0.0021 16.7 0.0 0.048 12.3 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_33 PF13671.1 CEH19612.1 - 0.0033 17.3 1.0 2.6 7.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CEH19612.1 - 0.0033 17.0 8.5 0.09 12.3 0.0 3.6 4 0 0 4 4 4 2 AAA domain UPF0079 PF02367.12 CEH19612.1 - 0.0035 16.9 0.5 2.8 7.5 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CEH19612.1 - 0.006 16.2 2.4 1.8 8.2 0.1 2.6 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.1 CEH19612.1 - 0.0065 16.3 0.5 0.71 9.8 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CEH19612.1 - 0.01 15.6 0.3 0.14 11.9 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 CEH19612.1 - 0.011 15.4 1.0 3.2 7.4 0.0 3.2 2 1 0 2 2 2 0 Archaeal ATPase GTP_EFTU PF00009.22 CEH19612.1 - 0.013 14.9 1.9 0.99 8.8 0.0 2.7 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain AAA PF00004.24 CEH19612.1 - 0.04 14.1 2.6 8.4 6.6 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 CEH19612.1 - 0.08 11.8 0.0 5.5 5.8 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_5 PF07728.9 CEH19612.1 - 0.088 12.5 0.8 37 4.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CEH19612.1 - 0.095 12.8 0.8 19 5.4 0.0 2.8 3 0 0 3 3 2 0 RNA helicase PduV-EutP PF10662.4 CEH19612.1 - 0.1 12.0 1.3 2.1 7.8 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.7 CEH19612.1 - 0.24 10.6 0.1 1.9 7.7 0.0 2.3 3 0 0 3 3 2 0 Poxvirus A32 protein AMP-binding PF00501.23 CEH19613.1 - 1.2e-213 709.0 0.1 2.2e-75 253.6 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 CEH19613.1 - 1.7e-140 467.1 0.0 4e-28 98.1 0.0 6.2 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 CEH19613.1 - 3.6e-28 97.6 9.6 7.9e-08 32.4 0.1 6.0 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 CEH19613.1 - 6.3e-11 43.0 1.0 0.0065 17.3 0.1 4.2 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain GH3 PF03321.8 CEH19613.1 - 0.0049 15.4 0.6 16 3.8 0.0 4.4 5 0 0 5 5 5 1 GH3 auxin-responsive promoter Transferase PF02458.10 CEH19613.1 - 0.091 11.1 0.0 11 4.3 0.0 3.0 3 0 0 3 3 3 0 Transferase family AATase PF07247.7 CEH19613.1 - 2.7 6.4 0.0 29 3.0 0.0 2.4 3 0 0 3 3 3 0 Alcohol acetyltransferase DUF1837 PF08878.6 CEH19613.1 - 8.3 5.9 0.0 52 3.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1837) zf-CCHC PF00098.18 CEH19614.1 - 2.1e-07 30.5 2.1 4e-07 29.6 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CEH19614.1 - 0.00017 21.5 0.1 0.00017 21.5 0.1 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_5 PF14787.1 CEH19614.1 - 0.0015 18.0 2.2 0.004 16.6 1.5 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RVP PF00077.15 CEH19614.1 - 0.016 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CEH19614.1 - 0.19 12.2 0.0 0.46 11.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF641 PF04859.7 CEH19614.1 - 2 8.1 7.5 0.43 10.3 2.7 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641)