# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Scs3p PF10261.9 EMG45163.1 - 5.2e-70 235.7 19.9 2.1e-69 233.7 19.9 1.8 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Dynamin_N PF00350.23 EMG45164.1 - 1e-14 54.9 4.2 1.3e-13 51.4 0.0 3.9 3 2 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EMG45164.1 - 2.9e-12 46.7 0.1 1.2e-09 38.3 0.0 4.1 4 2 0 4 4 4 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMG45164.1 - 6.5e-08 32.3 0.7 1e-05 25.2 0.1 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain cobW PF02492.19 EMG45164.1 - 0.0015 18.1 3.4 0.026 14.1 0.6 3.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EMG45164.1 - 0.004 17.4 0.2 9 6.5 0.0 3.6 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EMG45164.1 - 0.0047 16.9 4.5 0.24 11.3 0.4 3.1 2 1 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 EMG45164.1 - 0.068 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PglZ PF08665.12 EMG45164.1 - 9.8 6.2 9.3 3.3 7.8 0.1 3.8 4 0 0 4 4 4 0 PglZ domain Ureidogly_lyase PF04115.12 EMG45165.1 - 3.1e-60 203.1 0.1 3.6e-60 202.9 0.1 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase Sec15 PF04091.12 EMG45166.1 - 3e-70 237.1 13.8 3.9e-53 180.9 1.8 3.3 2 2 1 4 4 4 2 Exocyst complex subunit Sec15-like CtaG_Cox11 PF04442.14 EMG45166.1 - 1.6e-57 193.8 0.9 5.5e-57 192.0 0.1 2.3 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 BATS PF06968.13 EMG45167.1 - 6.5e-24 83.9 0.0 1.2e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EMG45167.1 - 7.6e-18 65.4 0.2 2.7e-17 63.7 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily INPP5B_PH PF16776.5 EMG45167.1 - 0.0018 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Ribosomal_L22e PF01776.17 EMG45168.1 - 1.8e-39 134.4 2.7 2.2e-39 134.2 2.7 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family ID PF18543.1 EMG45168.1 - 0.056 13.5 1.3 0.11 12.6 0.4 1.9 2 0 0 2 2 2 0 Intracellular delivery domain Proton_antipo_M PF00361.20 EMG45169.1 - 2.9e-25 89.1 9.0 3.2e-25 88.9 9.0 1.0 1 0 0 1 1 1 1 Proton-conducting membrane transporter Afi1 PF07792.12 EMG45175.1 - 0.031 14.8 5.3 0.074 13.5 1.0 2.8 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SH3_9 PF14604.6 EMG45176.1 - 1.8e-08 34.1 0.0 4.7e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain PX PF00787.24 EMG45176.1 - 8.8e-08 32.1 1.1 8.8e-08 32.1 1.1 2.6 3 0 0 3 3 3 1 PX domain SH3_1 PF00018.28 EMG45176.1 - 3e-07 29.9 0.0 6.2e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMG45176.1 - 0.00026 20.6 0.0 0.00067 19.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DNA_ligase_A_M PF01068.21 EMG45177.1 - 2.9e-60 203.4 0.9 5.8e-60 202.4 0.9 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EMG45177.1 - 4.4e-42 144.3 0.4 1e-41 143.2 0.4 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EMG45177.1 - 2e-25 89.3 0.0 7.6e-25 87.4 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EMG45177.1 - 0.00091 19.6 0.3 0.0018 18.6 0.3 1.5 1 0 0 1 1 1 1 RNA ligase ORC6 PF05460.13 EMG45177.1 - 0.0091 15.3 12.7 0.016 14.5 12.7 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DNA_ligase_OB_2 PF14743.6 EMG45177.1 - 0.022 14.8 0.5 1.9 8.5 0.0 2.8 2 0 0 2 2 2 0 DNA ligase OB-like domain Pox_Ag35 PF03286.14 EMG45177.1 - 0.2 11.4 10.4 0.4 10.4 10.4 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 EMG45177.1 - 2.4 6.8 3.7 3.8 6.2 3.7 1.2 1 0 0 1 1 1 0 Presenilin Pannexin_like PF12534.8 EMG45177.1 - 2.6 7.0 5.2 4.7 6.2 5.2 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Hid1 PF12722.7 EMG45177.1 - 3 5.9 8.8 4.8 5.2 8.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tox-GHH PF15636.6 EMG45177.1 - 3.2 7.8 5.5 7.4 6.6 3.2 2.4 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Acyltransferase PF01553.21 EMG45178.1 - 5.8e-09 35.7 0.0 3.2e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase YqfQ PF14181.6 EMG45178.1 - 0.048 13.9 0.4 0.086 13.0 0.4 1.3 1 0 0 1 1 1 0 YqfQ-like protein GPDPase_memb PF10110.9 EMG45178.1 - 0.053 12.3 7.7 0.1 11.3 7.7 1.4 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase HIG_1_N PF04588.13 EMG45179.1 - 1.1e-06 28.7 1.6 3.5e-06 27.1 1.6 1.8 1 0 0 1 1 1 1 Hypoxia induced protein conserved region COX16 PF14138.6 EMG45180.1 - 1e-20 74.0 1.6 1.2e-20 73.8 1.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 RT_RNaseH_2 PF17919.1 EMG45183.1 - 8.7e-21 73.8 0.0 2.7e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EMG45183.1 - 4.5e-17 62.3 2.7 9.2e-17 61.3 1.2 2.3 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 EMG45183.1 - 6.9e-17 61.7 0.0 1.9e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 EMG45183.1 - 3.4e-16 59.5 0.0 7.9e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF3552 PF12072.8 EMG45183.1 - 0.00038 19.9 16.3 0.00074 19.0 16.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DDE_3 PF13358.6 EMG45183.1 - 0.0051 16.6 0.2 0.02 14.6 0.1 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Prominin PF05478.11 EMG45183.1 - 0.006 14.6 5.7 0.02 12.9 5.7 1.8 1 0 0 1 1 1 1 Prominin V_ATPase_I PF01496.19 EMG45183.1 - 0.059 11.3 8.7 0.13 10.2 8.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 EMG45183.1 - 0.13 11.3 6.6 0.46 9.5 6.6 1.9 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EMG45183.1 - 0.84 8.5 17.0 1.9 7.3 17.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 EMG45183.1 - 0.84 10.2 18.0 2.5 8.7 18.0 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4200 PF13863.6 EMG45183.1 - 4.6 7.7 18.7 13 6.3 18.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PTR2 PF00854.21 EMG45184.1 - 1.8e-48 165.3 0.6 1.8e-48 165.3 0.6 1.3 1 1 0 1 1 1 1 POT family PUCC PF03209.15 EMG45184.1 - 0.049 12.6 0.0 0.049 12.6 0.0 1.7 2 0 0 2 2 2 0 PUCC protein DUF2721 PF11026.8 EMG45184.1 - 0.092 12.6 0.4 18 5.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Wzy_C PF04932.15 EMG45184.1 - 0.27 10.8 5.9 0.86 9.2 0.0 2.9 3 0 0 3 3 3 0 O-Antigen ligase DUF3169 PF11368.8 EMG45184.1 - 0.61 9.6 6.1 0.5 9.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF2207 PF09972.9 EMG45184.1 - 4.2 6.0 12.3 0.48 9.1 0.1 3.3 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) PTR2 PF00854.21 EMG45185.1 - 3.6e-46 157.8 4.6 4.9e-46 157.3 4.6 1.1 1 0 0 1 1 1 1 POT family UPF0242 PF06785.11 EMG45185.1 - 0.15 12.1 0.2 0.15 12.1 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RVT_2 PF07727.14 EMG45189.1 - 1.4e-66 224.6 0.0 2.8e-66 223.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) COX2 PF00116.20 EMG45190.1 - 1.7e-47 160.3 0.0 1.9e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain NADHdh PF00146.21 EMG45191.1 - 1.6e-25 90.0 1.2 1.6e-25 90.0 1.2 1.8 1 1 1 2 2 2 2 NADH dehydrogenase DUF3681 PF12442.8 EMG45191.1 - 0.074 13.5 3.9 2 9.0 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3681) Tetraspanin PF00335.20 EMG45191.1 - 1 9.0 5.2 0.59 9.8 3.5 1.5 1 1 1 2 2 2 0 Tetraspanin family Otopetrin PF03189.13 EMG45191.1 - 1 8.1 6.4 1 8.1 6.4 1.1 1 0 0 1 1 1 0 Otopetrin Bac_transf PF02397.16 EMG45191.1 - 1.9 8.0 4.1 0.98 9.0 0.1 2.0 2 0 0 2 2 2 0 Bacterial sugar transferase DEAD PF00270.29 EMG45192.1 - 2.8e-05 24.0 0.0 0.00012 21.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG45192.1 - 0.00087 19.6 2.8 0.0017 18.6 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RVT_2 PF07727.14 EMG45193.1 - 4.7e-76 255.6 0.2 8.4e-76 254.8 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EMG45193.1 - 2.1e-11 44.0 0.0 6.1e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 EMG45193.1 - 0.00071 19.1 0.0 0.0022 17.6 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 EMG45193.1 - 0.14 12.1 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1689 PF07954.11 EMG45194.1 - 2.4e-37 128.6 0.6 3e-37 128.3 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) Homeodomain PF00046.29 EMG45194.1 - 0.14 12.1 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Homeodomain tRNA-synt_2b PF00587.25 EMG45195.1 - 1.3e-30 106.7 0.0 3.1e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EMG45195.1 - 3.7e-16 59.1 0.2 9.2e-16 57.8 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 EMG45195.1 - 5.8e-11 42.3 0.0 1.2e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain LAGLIDADG_3 PF14528.6 EMG45195.1 - 0.0013 19.0 0.1 1.6 9.1 0.0 2.7 2 0 0 2 2 2 2 LAGLIDADG-like domain Sugar_tr PF00083.24 EMG45196.1 - 2.5e-43 148.6 2.0 3.4e-43 148.2 2.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG45196.1 - 1.5e-19 70.2 0.2 1.7e-19 70.0 0.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMG45196.1 - 0.00039 19.0 0.2 0.00051 18.6 0.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EMG45196.1 - 0.00039 19.1 1.1 0.00039 19.1 1.1 1.6 2 0 0 2 2 2 1 MFS/sugar transport protein ETRAMP PF09716.10 EMG45196.1 - 0.11 12.6 0.2 1.4 9.0 0.7 2.4 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Sugar_tr PF00083.24 EMG45197.1 - 7.3e-81 272.3 17.7 9e-81 272.0 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG45197.1 - 1.3e-23 83.5 15.4 1.3e-20 73.7 10.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMG45197.1 - 1e-07 30.9 23.8 1e-06 27.6 0.5 3.1 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EMG45197.1 - 0.00022 19.8 0.9 0.00022 19.8 0.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.32 EMG45199.1 - 5.2e-10 39.7 11.5 2.2e-05 25.1 1.2 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG45199.1 - 0.02 15.2 0.2 22 5.4 0.0 4.6 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain GTP_EFTU PF00009.27 EMG45200.1 - 3.1e-55 186.7 0.1 6e-55 185.8 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EMG45200.1 - 9.3e-43 145.1 0.0 2.2e-42 143.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EMG45200.1 - 1.3e-13 51.1 2.2 1.3e-13 51.1 2.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMG45200.1 - 0.00041 20.4 0.2 0.01 15.9 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EMG45200.1 - 9.5 6.2 8.7 0.42 10.5 1.3 2.4 3 0 0 3 3 3 0 Elongation factor Tu domain 4 Sugar_tr PF00083.24 EMG45202.1 - 3.5e-91 306.3 25.8 5.5e-91 305.7 25.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG45202.1 - 5e-18 65.1 44.1 4.1e-14 52.3 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Thiolase_N PF00108.23 EMG45203.1 - 8.9e-74 248.1 0.0 1.6e-73 247.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMG45203.1 - 4.1e-45 152.4 0.2 9.1e-45 151.3 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMG45203.1 - 0.00012 21.7 0.1 0.00037 20.2 0.1 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PBP1_TM PF14812.6 EMG45203.1 - 1.7 9.1 5.9 2.8 8.4 5.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Baculo_gp41 PF04700.12 EMG45204.1 - 0.076 12.8 0.1 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region NDT80_PhoG PF05224.12 EMG45205.1 - 2e-20 73.8 1.3 5.5e-20 72.4 0.0 2.2 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Thiolase_N PF00108.23 EMG45206.1 - 8.4e-83 277.7 0.4 1.2e-82 277.2 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMG45206.1 - 5.1e-46 155.3 0.0 1.1e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMG45206.1 - 0.00035 20.2 1.9 0.00082 19.0 0.6 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EMG45206.1 - 0.062 13.2 0.1 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2802 PF10975.8 EMG45206.1 - 0.17 12.0 0.1 3.1 8.0 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) SurE PF01975.17 EMG45208.1 - 3.7e-38 131.3 0.0 4.9e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Sec7_N PF12783.7 EMG45209.1 - 1.2e-39 135.8 6.7 1.2e-39 135.8 6.7 3.7 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EMG45209.1 - 2.2e-07 30.7 1.9 3.3e-06 26.9 0.0 3.3 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Staygreen PF12638.7 EMG45209.1 - 0.069 12.9 0.2 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Staygreen protein DUF1981 PF09324.10 EMG45209.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF1981) SSF PF00474.17 EMG45210.1 - 8.1e-21 74.3 24.7 1.5e-20 73.5 24.7 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family Orthoreo_P10 PF07204.11 EMG45210.1 - 0.027 14.4 0.3 0.17 11.9 0.0 2.4 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 UPF0154 PF03672.13 EMG45210.1 - 0.073 13.1 0.1 0.29 11.2 0.1 2.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DDE_3 PF13358.6 EMG45211.1 - 1.3e-10 41.2 0.0 5.2e-06 26.3 0.1 2.8 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EMG45211.1 - 6.1e-06 26.4 0.0 0.00037 20.7 0.0 2.9 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 EMG45211.1 - 0.00028 21.4 0.2 0.00092 19.8 0.3 1.8 1 1 0 1 1 1 1 Homeodomain-like domain Trypan_PARP PF05887.11 EMG45211.1 - 0.016 15.2 15.1 0.05 13.6 15.1 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) IL13 PF03487.13 EMG45211.1 - 0.023 14.5 0.5 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Interleukin-13 HTH_38 PF13936.6 EMG45211.1 - 0.13 12.0 0.0 24 4.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Dfp1_Him1_M PF08630.10 EMG45211.1 - 0.95 9.7 5.9 3.2 8.0 1.7 2.5 2 0 0 2 2 2 0 Dfp1/Him1, central region SSF PF00474.17 EMG45212.1 - 2.4e-23 82.7 27.9 4e-23 81.9 27.9 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family UPF0154 PF03672.13 EMG45212.1 - 0.1 12.7 0.1 1.6 8.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF848 PF05852.11 EMG45213.1 - 0.14 12.2 4.4 0.31 11.1 4.4 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Catalase PF00199.19 EMG45214.1 - 5e-105 351.8 0.8 6.8e-105 351.3 0.8 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EMG45214.1 - 7.5e-15 54.9 0.1 1.3e-13 51.0 0.1 2.4 2 0 0 2 2 2 1 Catalase-related immune-responsive Sugar_tr PF00083.24 EMG45215.1 - 5e-64 216.8 6.6 5.7e-64 216.6 6.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG45215.1 - 6.7e-11 41.7 3.3 6.7e-11 41.7 3.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily PigN PF04987.14 EMG45215.1 - 0.00027 19.9 0.5 0.0004 19.4 0.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Hyphal_reg_CWP PF11765.8 EMG45216.1 - 1.7e-102 342.8 10.7 1.9e-102 342.6 10.7 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 EMG45216.1 - 0.0037 16.8 8.1 0.0037 16.8 8.1 2.0 2 0 0 2 2 2 1 Hyphally regulated cell wall GPI-anchored protein 1 Hyd_WA PF06462.12 EMG45216.1 - 0.038 14.0 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Propeller VirArc_Nuclease PF12187.8 EMG45216.1 - 0.049 13.2 0.3 0.078 12.5 0.3 1.3 1 0 0 1 1 1 0 Viral/Archaeal nuclease GTP_EFTU PF00009.27 EMG45219.1 - 7.3e-60 201.8 0.6 9.8e-60 201.4 0.6 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EMG45219.1 - 2.1e-22 79.5 0.0 5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EMG45219.1 - 3.8e-21 75.3 1.7 3.8e-21 75.3 1.7 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMG45219.1 - 5.7e-05 23.2 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EMG45219.1 - 0.005 16.6 0.1 3.9 7.2 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EMG45219.1 - 0.015 14.9 0.4 0.034 13.7 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EMG45219.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase Hyphal_reg_CWP PF11765.8 EMG45221.1 - 3.1e-91 305.7 13.8 3.5e-91 305.5 13.8 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF4176 PF13780.6 EMG45221.1 - 0.055 13.5 0.8 0.25 11.4 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4176) Hyphal_reg_CWP PF11765.8 EMG45222.1 - 1.8e-125 418.2 12.5 2.3e-125 417.9 12.5 1.1 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 EMG45223.1 - 6.8e-23 79.9 107.9 4e-08 32.7 10.4 7.6 7 1 0 7 7 7 5 Hyphally regulated cell wall GPI-anchored protein 1 HalOD2 PF18547.1 EMG45223.1 - 0.00012 21.9 3.8 0.053 13.4 0.5 2.9 2 0 0 2 2 2 2 Halobacterial output domain 2 OrfB_Zn_ribbon PF07282.11 EMG45223.1 - 0.36 10.8 0.1 0.36 10.8 0.1 2.6 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Sugar_tr PF00083.24 EMG45225.1 - 1e-52 179.5 12.6 1.2e-52 179.4 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Hyr1 PF15789.5 EMG45226.1 - 7.4e-59 195.0 197.5 7.1e-10 38.3 13.6 10.0 9 1 1 10 10 10 9 Hyphally regulated cell wall GPI-anchored protein 1 Pput2613-deam PF14427.6 EMG45226.1 - 0.00023 21.0 32.4 0.44 10.5 0.6 7.4 1 1 7 8 8 8 7 Pput_2613-like deaminase DUF5628 PF18621.1 EMG45226.1 - 0.0031 18.0 57.2 3.4 8.2 1.2 8.2 1 1 7 8 8 8 8 Family of unknown function (DUF5628) Aconitase PF00330.20 EMG45227.1 - 6.8e-103 345.1 0.0 7.9e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Amidase PF01425.21 EMG45228.1 - 5.6e-18 65.1 0.0 6.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Candida_ALS PF05792.13 EMG45229.1 - 7e-24 84.1 21.1 2.8e-07 31.0 0.4 5.1 5 0 0 5 5 5 4 Candida agglutinin-like (ALS) DUF3104 PF11302.8 EMG45229.1 - 0.0015 18.2 0.2 3.6 7.4 0.0 3.8 2 1 2 4 4 4 2 Protein of unknown function (DUF3104) Candida_ALS PF05792.13 EMG45230.1 - 6.4e-13 49.0 4.2 0.00066 20.2 0.6 3.7 3 0 0 3 3 3 3 Candida agglutinin-like (ALS) DUF3104 PF11302.8 EMG45230.1 - 0.082 12.6 0.1 3.1 7.6 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3104) DDE_3 PF13358.6 EMG45231.1 - 8e-08 32.2 0.8 1.9e-07 30.9 0.5 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease Carot_N PF09150.10 EMG45231.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal Spore_YhcN_YlaJ PF09580.10 EMG45231.1 - 0.16 12.1 0.2 0.71 9.9 0.0 1.9 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF1644 PF07800.12 EMG45234.1 - 0.0012 18.9 0.3 0.0015 18.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) Ephrin_rec_like PF07699.13 EMG45234.1 - 0.13 12.1 0.3 0.29 10.9 0.3 1.6 1 1 0 1 1 1 0 Putative ephrin-receptor like zf-Sec23_Sec24 PF04810.15 EMG45234.1 - 0.17 11.9 0.2 0.17 11.9 0.2 1.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_4 PF13894.6 EMG45234.1 - 0.19 12.6 6.6 1.6 9.8 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3439 PF11921.8 EMG45235.1 - 0.01 15.8 4.2 0.012 15.6 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sugar_tr PF00083.24 EMG45236.1 - 0.00034 19.6 10.4 0.00036 19.5 10.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter HTH_Tnp_Tc5 PF03221.16 EMG45237.1 - 2.7e-05 24.1 0.2 6.9e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 EMG45237.1 - 0.0079 15.9 0.0 0.084 12.5 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF3844 PF12955.7 EMG45238.1 - 6.1e-05 23.1 9.4 9.9e-05 22.4 9.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF PF00008.27 EMG45238.1 - 0.011 16.1 4.3 0.017 15.4 4.3 1.3 1 0 0 1 1 1 0 EGF-like domain DUF1043 PF06295.12 EMG45238.1 - 0.028 14.4 0.8 0.16 11.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) GD_N PF16030.5 EMG45238.1 - 0.034 14.5 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 Serine protease gd N-terminus EGF_CA PF07645.15 EMG45238.1 - 0.1 12.9 7.7 0.17 12.1 7.7 1.3 1 0 0 1 1 1 0 Calcium-binding EGF domain EGF_2 PF07974.13 EMG45238.1 - 0.22 11.9 5.7 0.35 11.3 5.7 1.3 1 0 0 1 1 1 0 EGF-like domain EGF_3 PF12947.7 EMG45238.1 - 0.32 11.2 7.2 0.56 10.4 7.2 1.4 1 0 0 1 1 1 0 EGF domain ABC2_membrane PF01061.24 EMG45239.1 - 7.3e-06 25.5 2.1 9.9e-06 25.1 2.1 1.1 1 0 0 1 1 1 1 ABC-2 type transporter Candida_ALS PF05792.13 EMG45240.1 - 2.1e-08 34.6 102.7 0.0013 19.2 3.3 5.2 5 0 0 5 5 5 4 Candida agglutinin-like (ALS) Nucleoporin_FG PF13634.6 EMG45240.1 - 9.1e-05 23.2 8.1 0.03 15.2 2.9 2.3 1 1 1 2 2 2 2 Nucleoporin FG repeat region ABC_tran PF00005.27 EMG45241.1 - 1.9e-13 51.1 0.0 2.4e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EMG45241.1 - 2.3e-05 24.4 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EMG45241.1 - 0.00049 20.5 0.0 0.00063 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMG45241.1 - 0.00092 19.8 0.0 0.0014 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMG45241.1 - 0.0023 17.5 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EMG45241.1 - 0.0031 17.9 0.1 0.0048 17.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 EMG45241.1 - 0.0038 16.8 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 EMG45241.1 - 0.0076 16.1 0.2 0.051 13.4 0.1 1.8 1 1 1 2 2 2 1 Deoxynucleoside kinase AAA_22 PF13401.6 EMG45241.1 - 0.0078 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EMG45241.1 - 0.0078 16.3 0.1 0.016 15.3 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EMG45241.1 - 0.0091 15.7 0.8 0.025 14.3 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMG45241.1 - 0.011 16.3 0.1 0.016 15.7 0.1 1.3 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EMG45241.1 - 0.012 14.5 0.1 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class TsaE PF02367.17 EMG45241.1 - 0.013 15.5 0.2 0.029 14.4 0.2 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EMG45241.1 - 0.018 15.0 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EMG45241.1 - 0.025 14.7 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMG45241.1 - 0.027 14.9 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EMG45241.1 - 0.038 13.7 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 EMG45241.1 - 0.053 11.4 0.0 0.053 11.4 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_28 PF13521.6 EMG45241.1 - 0.098 12.9 0.1 0.15 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EMG45241.1 - 0.15 11.8 0.1 0.19 11.5 0.1 1.3 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EMG45241.1 - 0.16 12.4 0.0 0.22 11.9 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NMT1 PF09084.11 EMG45242.1 - 4.2e-30 105.3 0.0 5.7e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Peptidase_M24 PF00557.24 EMG45243.1 - 2.2e-13 50.4 0.0 2.4e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 PPO1_DWL PF12142.8 EMG45244.1 - 0.11 12.3 1.7 0.32 10.8 1.0 2.1 2 1 0 2 2 2 0 Polyphenol oxidase middle domain NADHdh_A3 PF14987.6 EMG45245.1 - 0.001 19.3 0.3 0.0028 17.9 0.3 1.8 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 Hyr1 PF15789.5 EMG45246.1 - 0.00035 20.1 6.7 0.00035 20.1 6.7 2.8 2 2 0 2 2 2 1 Hyphally regulated cell wall GPI-anchored protein 1 Hyr1 PF15789.5 EMG45247.1 - 7e-37 124.7 99.5 1.8e-11 43.4 13.2 8.0 5 4 3 8 8 8 5 Hyphally regulated cell wall GPI-anchored protein 1 DSRB PF10781.9 EMG45247.1 - 0.00014 21.4 0.0 17 5.1 0.0 4.0 4 0 0 4 4 4 3 Dextransucrase DSRB Imm53 PF15580.6 EMG45247.1 - 0.0022 17.7 1.8 14 5.5 0.0 3.2 3 0 0 3 3 3 3 Immunity protein 53 SNAP-25 PF00835.19 EMG45247.1 - 0.0041 17.4 1.2 16 5.9 0.0 3.3 3 0 0 3 3 3 2 SNAP-25 family N_BRCA1_IG PF16158.5 EMG45247.1 - 0.24 12.1 8.5 5.1 7.9 0.2 3.1 2 1 1 3 3 3 0 Ig-like domain from next to BRCA1 gene DUF5052 PF16475.5 EMG45247.1 - 0.43 10.2 7.7 15 5.1 0.0 3.4 2 1 1 4 4 4 0 Domain of unknown function (DUF5052) OB_aCoA_assoc PF01796.17 EMG45247.1 - 1.3 9.1 12.8 12 6.0 0.4 4.4 2 2 3 5 5 5 0 DUF35 OB-fold domain, acyl-CoA-associated NMT1 PF09084.11 EMG45248.1 - 6.1e-31 108.0 0.0 6.8e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EMG45248.1 - 0.0083 15.9 0.0 0.0086 15.8 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family Hyr1 PF15789.5 EMG45249.1 - 7.6e-26 89.4 74.2 5.7e-08 32.2 9.7 5.8 5 1 0 5 5 5 4 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG45249.1 - 6.2e-07 29.9 18.9 0.34 11.4 0.7 4.1 1 1 3 4 4 4 4 Family of unknown function (DUF5628) Pput2613-deam PF14427.6 EMG45249.1 - 0.056 13.3 6.3 1.7 8.6 0.2 3.6 1 1 3 4 4 4 0 Pput_2613-like deaminase DUF3254 PF11630.8 EMG45249.1 - 0.092 12.9 8.2 13 6.0 0.1 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3254) US10 PF17617.2 EMG45249.1 - 0.17 11.9 1.4 24 4.9 0.1 2.8 1 1 2 3 3 3 0 Viral unique short region 10 HalOD2 PF18547.1 EMG45249.1 - 2.9 7.9 9.6 63 3.6 0.1 4.2 4 0 0 4 4 4 0 Halobacterial output domain 2 Aconitase PF00330.20 EMG45250.1 - 9.6e-46 156.7 0.1 1.1e-45 156.5 0.1 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Hyr1 PF15789.5 EMG45251.1 - 3.6e-24 84.0 68.7 2.4e-09 36.6 13.6 4.8 4 1 0 4 4 4 4 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG45251.1 - 0.091 13.2 17.2 1.8 9.0 1.3 3.5 1 1 2 3 3 3 0 Family of unknown function (DUF5628) MDM31_MDM32 PF08118.11 EMG45252.1 - 1.6e-34 119.5 0.3 1.7e-34 119.4 0.3 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Hyr1 PF15789.5 EMG45253.1 - 4.9e-25 86.8 79.1 2.3e-10 39.8 12.9 5.2 5 0 0 5 5 5 5 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG45253.1 - 0.0057 17.1 16.4 1.2 9.7 1.2 3.5 1 1 2 3 3 3 3 Family of unknown function (DUF5628) Pput2613-deam PF14427.6 EMG45253.1 - 0.83 9.6 7.9 1.9 8.4 0.6 3.1 2 1 2 4 4 4 0 Pput_2613-like deaminase FAM124 PF15067.6 EMG45253.1 - 1.6 8.3 3.3 22 4.6 0.0 2.7 3 0 0 3 3 3 0 FAM124 family Hyphal_reg_CWP PF11765.8 EMG45254.1 - 2.2e-41 141.9 0.1 2.3e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal PTS_2-RNA PF01885.16 EMG45254.1 - 0.041 13.9 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family MFS_1 PF07690.16 EMG45255.1 - 8e-10 38.2 4.8 9.5e-10 37.9 4.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 EMG45256.1 - 2.3e-13 50.1 0.0 3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EMG45257.1 - 1.2e-12 47.8 0.0 1.5e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Hyr1 PF15789.5 EMG45258.1 - 1.4e-05 24.5 4.0 1.4e-05 24.5 4.0 3.9 4 1 0 4 4 4 2 Hyphally regulated cell wall GPI-anchored protein 1 YcgR PF07317.12 EMG45258.1 - 0.11 12.4 1.1 2.6 8.0 0.2 2.2 2 0 0 2 2 2 0 Flagellar regulator YcgR LAMTOR5 PF16672.5 EMG45258.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 DUF5628 PF18621.1 EMG45258.1 - 0.18 12.3 6.4 2.4 8.6 0.4 2.6 1 1 1 3 3 3 0 Family of unknown function (DUF5628) SSF PF00474.17 EMG45259.1 - 1e-08 34.5 0.8 1.1e-08 34.4 0.8 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family Candida_ALS PF05792.13 EMG45261.1 - 1.5e-14 54.3 100.6 7.7e-08 32.8 11.5 5.2 5 0 0 5 5 5 4 Candida agglutinin-like (ALS) Nucleoporin_FG PF13634.6 EMG45261.1 - 0.47 11.3 6.5 0.12 13.2 3.4 1.8 2 1 0 2 2 2 0 Nucleoporin FG repeat region Hyr1 PF15789.5 EMG45263.1 - 2.7e-28 97.2 70.7 5e-11 42.0 16.5 5.5 4 2 0 4 4 4 4 Hyphally regulated cell wall GPI-anchored protein 1 SNAP-25 PF00835.19 EMG45263.1 - 0.022 15.0 4.4 1.4 9.3 0.3 3.2 2 1 1 3 3 3 0 SNAP-25 family Imm53 PF15580.6 EMG45263.1 - 0.045 13.5 0.2 32 4.3 0.0 3.0 3 0 0 3 3 3 0 Immunity protein 53 Hyphal_reg_CWP PF11765.8 EMG45264.1 - 1.9e-40 138.8 2.5 2.3e-40 138.6 2.5 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 EMG45265.1 - 1.8e-18 65.8 71.8 2.1e-08 33.5 14.0 4.8 5 0 0 5 5 5 4 Hyphally regulated cell wall GPI-anchored protein 1 Pput2613-deam PF14427.6 EMG45265.1 - 0.019 14.9 8.5 6.2 6.7 0.3 3.9 1 1 3 4 4 4 0 Pput_2613-like deaminase DUF5628 PF18621.1 EMG45265.1 - 0.087 13.3 14.7 3.7 8.0 0.7 3.3 1 1 0 3 3 3 0 Family of unknown function (DUF5628) Minor_capsid_1 PF10665.9 EMG45265.1 - 0.13 12.5 3.0 9 6.5 0.1 3.5 1 1 3 4 4 4 0 Minor capsid protein Hyr1 PF15789.5 EMG45266.1 - 2.7e-25 87.6 74.3 7.2e-09 35.0 13.0 4.3 4 0 0 4 4 4 4 Hyphally regulated cell wall GPI-anchored protein 1 Pput2613-deam PF14427.6 EMG45266.1 - 2.6e-05 24.1 6.1 0.38 10.7 0.1 3.1 1 1 2 3 3 3 3 Pput_2613-like deaminase MMPL PF03176.15 EMG45266.1 - 0.17 10.8 5.6 7.8 5.3 0.3 2.9 1 1 1 3 3 3 0 MMPL family Chitin_bind_4 PF00379.23 EMG45266.1 - 0.86 10.2 18.2 7.2 7.2 1.2 4.4 4 0 0 4 4 4 0 Insect cuticle protein DUF3254 PF11630.8 EMG45266.1 - 0.95 9.7 5.2 13 6.0 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3254) DUF2020 PF09449.10 EMG45266.1 - 1.8 8.4 6.2 4.6 7.1 0.3 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF2020) DUF5628 PF18621.1 EMG45266.1 - 3.1 8.3 24.4 1.2 9.6 0.7 3.9 3 1 0 4 4 4 0 Family of unknown function (DUF5628) Herpes_LMP1 PF05297.11 EMG45266.1 - 7.5 5.6 15.7 11 5.1 15.7 1.3 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PDR_CDR PF06422.12 EMG45267.1 - 4.4e-24 84.2 0.3 9.1e-24 83.2 0.0 1.6 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane PF01061.24 EMG45267.1 - 5e-14 52.2 5.2 5e-14 52.2 5.2 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EMG45267.1 - 0.00023 20.4 0.8 0.0003 20.0 0.8 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF1586 PF07625.11 EMG45267.1 - 0.079 13.0 3.0 0.23 11.5 3.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) Hyr1 PF15789.5 EMG45268.1 - 9.3e-15 53.9 57.3 2.5e-08 33.3 10.5 5.3 5 0 0 5 5 5 4 Hyphally regulated cell wall GPI-anchored protein 1 CopC PF04234.12 EMG45268.1 - 0.025 15.6 5.2 0.88 10.7 1.2 2.5 1 1 1 2 2 2 0 CopC domain Minor_capsid_1 PF10665.9 EMG45268.1 - 0.14 12.3 0.9 1.1 9.5 0.3 2.2 1 1 1 2 2 2 0 Minor capsid protein SH3_6 PF12913.7 EMG45268.1 - 0.15 11.7 1.0 0.22 11.1 0.2 1.7 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) Flocculin_t3 PF13928.6 EMG45269.1 - 3e-10 40.4 30.6 3e-10 40.4 30.6 3.9 2 1 1 3 3 3 1 Flocculin type 3 repeat Ribosomal_S4e PF00900.20 EMG45270.1 - 1.2e-28 98.8 0.2 4.3e-28 97.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 EMG45270.1 - 1.5e-25 88.6 0.2 2.9e-25 87.6 0.0 1.6 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus KOW PF00467.29 EMG45270.1 - 6.7e-06 25.9 3.5 6.7e-06 25.9 3.5 2.8 3 0 0 3 3 3 1 KOW motif FAD_binding_3 PF01494.19 EMG45271.1 - 9.6e-11 41.5 0.0 1.1e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMG45271.1 - 1.1e-09 38.3 1.6 1.7e-05 24.6 2.7 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMG45271.1 - 2.1e-09 37.1 3.2 1.1e-05 24.9 0.2 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMG45271.1 - 1.7e-08 34.9 0.5 1.1e-05 25.8 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMG45271.1 - 4.3e-08 32.9 0.0 5.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMG45271.1 - 6.9e-08 32.6 0.3 1.5e-07 31.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMG45271.1 - 1.6e-07 30.8 1.8 2.9e-07 29.9 1.8 1.5 1 1 1 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EMG45271.1 - 2.5e-07 30.4 1.9 5.8e-05 22.6 0.1 2.2 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EMG45271.1 - 3.3e-07 29.5 1.7 0.0014 17.5 0.6 2.0 1 1 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 EMG45271.1 - 4.1e-07 29.4 1.6 0.004 16.3 1.2 2.0 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 EMG45271.1 - 5.7e-07 28.6 1.5 1.4e-05 24.0 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EMG45271.1 - 1.2e-05 24.8 5.1 0.0016 17.8 1.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMG45271.1 - 0.00071 18.8 3.3 0.0046 16.1 1.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EMG45271.1 - 0.0014 17.9 1.2 0.0015 17.8 0.2 1.6 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 EMG45271.1 - 0.0036 17.6 0.7 0.079 13.2 0.3 2.1 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.6 EMG45271.1 - 0.22 11.5 1.9 9.2 6.2 0.3 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Hyr1 PF15789.5 EMG45273.1 - 1e-09 37.8 44.5 2.7e-09 36.4 12.9 3.9 2 1 1 3 3 3 3 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG45273.1 - 0.22 12.0 10.1 0.58 10.7 0.9 2.4 1 1 0 2 2 2 0 Family of unknown function (DUF5628) Hyr1 PF15789.5 EMG45277.1 - 4.6e-28 96.5 46.9 4.9e-11 42.0 7.5 4.3 4 1 0 4 4 4 4 Hyphally regulated cell wall GPI-anchored protein 1 Pput2613-deam PF14427.6 EMG45277.1 - 0.027 14.3 0.4 0.14 12.0 0.1 2.0 1 1 1 2 2 2 0 Pput_2613-like deaminase DUF5628 PF18621.1 EMG45277.1 - 1 9.8 15.9 4.9 7.7 0.7 3.7 1 1 3 4 4 4 0 Family of unknown function (DUF5628) Hyr1 PF15789.5 EMG45278.1 - 1.3e-24 85.5 29.7 1.4e-11 43.7 7.4 4.1 4 0 0 4 4 4 3 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG45278.1 - 2.5 8.6 11.6 4.2 7.9 0.4 3.7 1 1 3 4 4 4 0 Family of unknown function (DUF5628) Hyr1 PF15789.5 EMG45279.1 - 2.7e-12 46.0 24.1 1.1e-07 31.3 10.0 2.3 2 0 0 2 2 2 2 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG45279.1 - 0.00059 20.3 5.3 0.16 12.4 0.5 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5628) Pput2613-deam PF14427.6 EMG45279.1 - 0.088 12.7 0.4 0.69 9.8 0.1 1.9 1 1 1 2 2 2 0 Pput_2613-like deaminase DUF3254 PF11630.8 EMG45279.1 - 0.31 11.2 2.0 4.3 7.6 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3254) DLH PF01738.18 EMG45282.1 - 2.4e-11 43.6 0.0 2.7e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family PilJ PF13675.6 EMG45283.1 - 0.0089 16.0 1.4 0.012 15.7 1.4 1.1 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term PEP-utilisers_N PF05524.13 EMG45283.1 - 0.012 15.8 5.3 0.015 15.5 5.0 1.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal SCO1-SenC PF02630.14 EMG45283.1 - 0.027 14.4 0.5 2.3 8.1 0.0 2.3 1 1 1 2 2 2 0 SCO1/SenC DUF2730 PF10805.8 EMG45283.1 - 0.038 14.1 11.2 0.054 13.6 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Hema_stalk PF08720.10 EMG45283.1 - 0.045 13.4 1.4 0.048 13.4 1.4 1.2 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk SlyX PF04102.12 EMG45283.1 - 0.054 14.1 7.7 2.8 8.6 2.7 3.2 1 1 1 2 2 2 0 SlyX CPSase_L_D3 PF02787.19 EMG45283.1 - 0.09 13.1 4.6 0.13 12.6 4.6 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain YlqD PF11068.8 EMG45283.1 - 0.11 12.8 15.8 0.22 11.9 15.8 1.4 1 1 0 1 1 1 0 YlqD protein BST2 PF16716.5 EMG45283.1 - 0.25 12.0 20.6 1.4 9.5 1.9 3.0 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF1664 PF07889.12 EMG45283.1 - 0.3 11.1 10.8 0.36 10.9 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlxA PF14282.6 EMG45283.1 - 0.33 11.0 19.2 2.8 8.0 6.9 2.2 1 1 1 2 2 2 0 FlxA-like protein COG5 PF10392.9 EMG45283.1 - 0.33 11.1 9.4 0.95 9.6 9.4 1.7 1 1 0 1 1 1 0 Golgi transport complex subunit 5 LAG1-DNAbind PF09271.11 EMG45283.1 - 0.38 11.4 6.2 0.51 10.9 6.2 1.3 1 1 0 1 1 1 0 LAG1, DNA binding DivIC PF04977.15 EMG45283.1 - 0.41 10.5 17.2 0.28 11.0 5.7 3.1 1 1 2 3 3 3 0 Septum formation initiator DUF4200 PF13863.6 EMG45283.1 - 0.53 10.7 23.9 3 8.3 6.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 EMG45283.1 - 0.61 10.4 7.6 0.35 11.2 3.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 EMG45283.1 - 0.66 10.7 14.2 2.3 8.9 13.4 2.2 1 1 0 1 1 1 0 Initiation control protein YabA Phage_GPO PF05929.11 EMG45283.1 - 0.66 9.5 12.6 0.74 9.4 12.6 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase HutP PF09021.11 EMG45283.1 - 1 9.7 4.7 2.1 8.7 4.8 1.5 1 1 0 1 1 1 0 HutP YvrJ PF12841.7 EMG45283.1 - 1 9.0 5.4 1.9 8.1 0.3 3.0 3 0 0 3 3 3 0 YvrJ protein family Wbp11 PF09429.10 EMG45283.1 - 1.1 9.7 17.0 1.5 9.3 3.6 2.2 1 1 1 2 2 2 0 WW domain binding protein 11 Z1 PF10593.9 EMG45283.1 - 1.3 8.5 6.9 1.6 8.2 6.9 1.0 1 0 0 1 1 1 0 Z1 domain APG6_N PF17675.1 EMG45283.1 - 1.6 9.2 21.8 1.5 9.4 10.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region HOOK PF05622.12 EMG45283.1 - 1.6 6.7 22.5 10 4.1 22.5 1.8 1 1 0 1 1 1 0 HOOK protein ACCA PF03255.14 EMG45283.1 - 2 8.3 14.0 0.44 10.4 3.0 2.1 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TSC22 PF01166.18 EMG45283.1 - 2.4 8.5 13.5 6.2 7.2 2.7 3.3 1 1 2 3 3 3 0 TSC-22/dip/bun family UPF0515 PF15135.6 EMG45283.1 - 2.5 7.4 5.6 2.8 7.2 5.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 ABC_tran_Xtn PF12848.7 EMG45283.1 - 2.7 8.1 15.0 2 8.5 9.1 2.1 1 1 1 2 2 2 0 ABC transporter DUF16 PF01519.16 EMG45283.1 - 2.9 8.4 15.4 17 6.0 15.4 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 Val_tRNA-synt_C PF10458.9 EMG45283.1 - 3 8.2 17.0 1.9 8.9 0.7 3.1 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm CdiI_2 PF18593.1 EMG45283.1 - 3 8.5 5.4 3.3 8.4 0.4 2.1 1 1 1 2 2 2 0 CdiI immunity protein DUF4407 PF14362.6 EMG45283.1 - 4.2 6.6 12.3 5.3 6.3 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS6_N PF14661.6 EMG45283.1 - 4.5 6.8 12.3 5.2 6.6 12.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus LUC7 PF03194.15 EMG45283.1 - 4.6 6.8 15.7 5.9 6.5 15.7 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Csm1_N PF18504.1 EMG45283.1 - 5 7.5 19.6 2.7 8.4 2.1 3.1 1 1 2 3 3 3 0 Csm1 N-terminal domain CCDC-167 PF15188.6 EMG45283.1 - 6.2 7.2 18.3 2.6 8.5 3.1 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4140 PF13600.6 EMG45283.1 - 8.2 6.9 11.8 2.2e+03 -0.8 11.8 2.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4078 PF13300.6 EMG45283.1 - 8.9 6.7 12.3 0.68 10.3 5.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) DUF1690 PF07956.11 EMG45283.1 - 9.5 6.6 18.2 16 5.9 18.2 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) AA_permease PF00324.21 EMG45284.1 - 1.7e-10 40.1 8.5 1.9e-10 40.0 8.5 1.0 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.17 EMG45284.1 - 0.00093 18.6 1.4 0.00099 18.5 1.4 1.0 1 0 0 1 1 1 1 Sodium:alanine symporter family AA_permease_2 PF13520.6 EMG45284.1 - 0.12 11.2 4.9 0.14 11.0 4.9 1.0 1 0 0 1 1 1 0 Amino acid permease Hyr1 PF15789.5 EMG45285.1 - 4.4e-13 48.5 39.5 5e-07 29.1 10.8 3.2 3 0 0 3 3 3 2 Hyphally regulated cell wall GPI-anchored protein 1 E1_DerP2_DerF2 PF02221.15 EMG45285.1 - 0.00047 20.6 0.8 0.89 10.0 0.1 2.2 1 1 1 2 2 2 2 ML domain Bile_Hydr_Trans PF04775.14 EMG45285.1 - 0.0022 18.1 0.2 1.9 8.6 0.0 2.6 1 1 2 3 3 3 2 Acyl-CoA thioester hydrolase/BAAT N-terminal region LAMTOR5 PF16672.5 EMG45285.1 - 0.0023 17.8 0.2 1.9 8.5 0.0 2.3 1 1 1 2 2 2 2 Ragulator complex protein LAMTOR5 SH3_10 PF17902.1 EMG45285.1 - 0.003 17.6 0.2 0.71 10.0 0.1 2.2 2 0 0 2 2 2 1 SH3 domain PKD PF00801.20 EMG45285.1 - 0.0032 17.3 2.7 0.52 10.2 0.4 2.2 1 1 1 2 2 2 2 PKD domain DUF2771 PF10969.8 EMG45285.1 - 0.0032 17.5 0.5 1.8 8.6 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2771) DUF5628 PF18621.1 EMG45285.1 - 0.012 16.1 5.5 1.4 9.4 0.7 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5628) Polyketide_cyc2 PF10604.9 EMG45285.1 - 0.022 15.0 9.6 0.77 10.0 1.6 2.2 1 1 1 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Lipocalin_9 PF17186.4 EMG45285.1 - 0.031 14.5 1.1 1.4 9.2 0.1 2.1 1 1 1 2 2 2 0 Lipocalin-like domain MAR_sialic_bdg PF10564.9 EMG45285.1 - 0.061 13.4 1.2 12 6.0 0.0 2.6 3 0 0 3 3 3 0 Sialic-acid binding micronemal adhesive repeat DUF5627 PF18620.1 EMG45285.1 - 0.076 12.9 7.7 3.1 7.7 0.3 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5627) VD10_N PF08476.10 EMG45285.1 - 0.1 12.3 7.9 17 5.2 0.2 3.3 3 0 0 3 3 3 0 Viral D10 N-terminal OSR1_C PF12202.8 EMG45285.1 - 0.14 12.4 0.3 35 4.7 0.0 2.8 3 0 0 3 3 3 0 Oxidative-stress-responsive kinase 1 C-terminal domain Peptidase_Prp PF04327.12 EMG45285.1 - 0.37 11.0 2.8 22 5.4 0.1 2.7 1 1 2 3 3 3 0 Cysteine protease Prp TF_Zn_Ribbon PF08271.12 EMG45285.1 - 0.69 9.5 4.4 11 5.6 0.2 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding Big_2 PF02368.18 EMG45285.1 - 0.88 9.5 10.2 1.4 8.8 0.9 2.6 1 1 2 3 3 3 0 Bacterial Ig-like domain (group 2) DUF3805 PF12712.7 EMG45285.1 - 1.4 9.0 4.1 13 5.9 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3805) Phage_X PF05155.15 EMG45286.1 - 0.082 13.3 0.0 0.11 13.0 0.0 1.3 1 1 0 1 1 1 0 Phage X family Phage_X PF05155.15 EMG45287.1 - 0.082 13.3 0.0 0.11 13.0 0.0 1.3 1 1 0 1 1 1 0 Phage X family Hyr1 PF15789.5 EMG45288.1 - 1.7e-21 75.5 55.4 1.3e-08 34.2 15.1 3.4 3 0 0 3 3 3 3 Hyphally regulated cell wall GPI-anchored protein 1 Pput2613-deam PF14427.6 EMG45288.1 - 0.00011 22.1 1.4 0.18 11.7 0.1 2.1 1 1 1 2 2 2 2 Pput_2613-like deaminase DUF5628 PF18621.1 EMG45288.1 - 1.5 9.3 16.9 0.78 10.2 1.5 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5628) Tir_receptor_C PF07489.11 EMG45289.1 - 2.3 8.1 20.6 3 7.8 20.6 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Fungal_trans PF04082.18 EMG45290.1 - 0.0053 15.8 0.0 0.0057 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hyr1 PF15789.5 EMG45291.1 - 8.4e-18 63.6 52.0 6.3e-09 35.2 14.9 4.1 3 1 0 3 3 3 3 Hyphally regulated cell wall GPI-anchored protein 1 Pput2613-deam PF14427.6 EMG45291.1 - 0.012 15.5 1.8 0.45 10.4 0.1 2.1 1 1 1 2 2 2 0 Pput_2613-like deaminase DUF5628 PF18621.1 EMG45291.1 - 0.015 15.8 5.1 0.54 10.8 0.5 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5628) Hyr1 PF15789.5 EMG45292.1 - 3.2e-19 68.2 51.9 6.8e-11 41.5 17.7 3.4 3 1 0 3 3 3 3 Hyphally regulated cell wall GPI-anchored protein 1 CopC PF04234.12 EMG45292.1 - 0.089 13.8 5.7 1 10.4 0.6 2.7 1 1 2 3 3 3 0 CopC domain Hydin_ADK PF17213.3 EMG45292.1 - 0.23 11.7 3.5 0.27 11.5 3.5 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Hyr1 PF15789.5 EMG45293.1 - 1.5e-15 56.5 31.4 1.3e-13 50.2 14.3 2.2 2 0 0 2 2 2 2 Hyphally regulated cell wall GPI-anchored protein 1 TauD PF02668.16 EMG45294.1 - 0.47 10.2 1.8 14 5.3 1.6 2.3 1 1 1 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family TOBE PF03459.17 EMG45294.1 - 5.4 7.4 11.7 1.7 9.0 1.0 3.0 2 1 1 3 3 3 0 TOBE domain Hyr1 PF15789.5 EMG45295.1 - 3.7e-05 23.2 3.8 3.7e-05 23.2 3.8 2.4 2 1 0 2 2 2 2 Hyphally regulated cell wall GPI-anchored protein 1 Hyr1 PF15789.5 EMG45296.1 - 1e-19 69.8 37.0 7.4e-08 31.8 10.5 3.2 3 0 0 3 3 3 3 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG45296.1 - 0.0042 17.6 12.4 1.3 9.6 0.6 3.1 1 1 0 3 3 3 3 Family of unknown function (DUF5628) SBBP PF06739.11 EMG45296.1 - 0.46 10.5 11.2 8.7 6.4 0.9 3.8 3 1 1 4 4 4 0 Beta-propeller repeat 2-Hacid_dh_C PF02826.19 EMG45297.1 - 4.9e-12 45.6 0.0 5.4e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMG45298.1 - 4.9e-12 45.6 0.0 5.4e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hyr1 PF15789.5 EMG45300.1 - 1.9e-08 33.7 9.3 1.9e-08 33.7 9.3 2.1 2 0 0 2 2 2 2 Hyphally regulated cell wall GPI-anchored protein 1 OSR1_C PF12202.8 EMG45300.1 - 0.0051 17.0 0.1 0.82 9.9 0.0 2.1 2 0 0 2 2 2 2 Oxidative-stress-responsive kinase 1 C-terminal domain Polyketide_cyc2 PF10604.9 EMG45300.1 - 0.017 15.4 1.4 0.021 15.1 1.4 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport SRP9-21 PF05486.12 EMG45300.1 - 0.061 13.7 0.3 0.083 13.3 0.3 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Big_2 PF02368.18 EMG45300.1 - 0.078 12.9 3.3 0.056 13.3 1.0 1.8 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 2) VD10_N PF08476.10 EMG45300.1 - 0.11 12.2 2.3 9.4 6.0 0.2 2.2 2 0 0 2 2 2 0 Viral D10 N-terminal NPCBM_assoc PF10633.9 EMG45300.1 - 0.84 9.9 5.0 19 5.6 1.5 2.8 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF4596 PF15363.6 EMG45300.1 - 2.2 8.6 12.4 3.3 8.0 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4596) Hyr1 PF15789.5 EMG45302.1 - 1.5e-08 34.0 17.8 0.00011 21.6 4.4 2.1 2 0 0 2 2 2 2 Hyphally regulated cell wall GPI-anchored protein 1 RPA43_OB PF17875.1 EMG45304.1 - 5.9e-21 75.4 10.6 6.5e-21 75.2 0.4 3.3 2 2 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EMG45304.1 - 6.5e-13 48.9 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 CorA PF01544.18 EMG45305.1 - 2e-09 37.2 1.7 3.1e-09 36.6 1.7 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein LsmAD PF06741.13 EMG45307.1 - 3.3e-30 104.4 3.0 3.3e-30 104.4 3.0 2.7 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 EMG45307.1 - 1.2e-14 54.1 0.0 3.9e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.15 EMG45307.1 - 0.012 15.2 0.6 0.048 13.4 0.6 2.1 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Sec6 PF06046.13 EMG45308.1 - 6.2e-177 589.4 9.9 1.1e-176 588.6 9.9 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF5082 PF16888.5 EMG45308.1 - 0.02 15.2 3.8 0.07 13.4 3.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF5344 PF17279.2 EMG45308.1 - 0.022 15.3 0.3 0.23 12.1 0.3 2.9 1 1 0 1 1 1 0 Family of unknown function (DUF5344) DUF4125 PF13526.6 EMG45308.1 - 0.071 12.7 0.8 0.23 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) DUF489 PF04356.12 EMG45308.1 - 2.4 8.1 6.4 47 3.9 0.5 4.4 4 1 2 6 6 6 0 Protein of unknown function (DUF489) NPV_P10 PF05531.12 EMG45308.1 - 4.7 7.8 10.6 31 5.1 0.3 4.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Ribosomal_S24e PF01282.19 EMG45309.1 - 4.8e-35 119.4 0.0 7.3e-35 118.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e ADH_zinc_N PF00107.26 EMG45311.1 - 3.2e-10 40.1 0.0 4.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG45311.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMG45311.1 - 0.031 15.3 0.0 0.056 14.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Amidohydro_1 PF01979.20 EMG45312.1 - 8.8e-42 143.6 0.1 4.2e-22 78.9 0.2 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EMG45312.1 - 7e-13 48.9 0.1 4.5e-08 33.0 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family DUF2347 PF09804.9 EMG45313.1 - 5.6e-68 229.6 4.4 6.7e-34 117.8 0.2 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EMG45313.1 - 1.2e-17 64.6 7.8 2.2e-07 31.2 0.1 3.2 1 1 2 3 3 3 3 Domain of unknown function (DUF4484) Mpv17_PMP22 PF04117.12 EMG45314.1 - 6.4e-06 26.3 1.0 6.4e-06 26.3 1.0 2.5 3 0 0 3 3 3 1 Mpv17 / PMP22 family Hus1 PF04005.12 EMG45315.1 - 0.21 10.7 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 Hus1-like protein ArfGap PF01412.18 EMG45316.1 - 9.4e-35 119.2 0.5 9.4e-35 119.2 0.5 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Pilosulin PF17499.2 EMG45317.1 - 0.1 12.8 3.1 0.22 11.7 2.4 1.9 1 1 1 2 2 2 0 Ant venom peptides Tim44 PF04280.15 EMG45318.1 - 9.2e-38 129.6 0.1 2.2e-37 128.4 0.1 1.7 1 0 0 1 1 1 1 Tim44-like domain HAD_2 PF13419.6 EMG45319.1 - 2.3e-13 50.6 0.0 4.8e-13 49.6 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMG45319.1 - 4.5e-11 43.4 0.0 1.7e-06 28.5 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMG45319.1 - 7.5e-08 33.0 0.0 9.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EMG45319.1 - 0.11 12.6 0.0 1.5 9.0 0.0 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMG45319.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Ribonucleas_3_3 PF14622.6 EMG45320.1 - 0.0014 18.8 0.0 0.0037 17.4 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EMG45320.1 - 0.038 14.6 0.0 0.21 12.2 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease III domain AAA PF00004.29 EMG45321.1 - 4.2e-40 137.2 0.0 7.3e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMG45321.1 - 1.5e-10 40.7 0.5 2.9e-10 39.8 0.5 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EMG45321.1 - 3.3e-10 39.8 0.1 6.4e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EMG45321.1 - 4.6e-06 27.0 0.2 0.019 15.2 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 EMG45321.1 - 9.7e-06 25.8 0.0 3.6e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EMG45321.1 - 2.2e-05 23.8 0.0 3.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EMG45321.1 - 0.00017 22.0 0.2 0.0044 17.4 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EMG45321.1 - 0.0002 21.3 0.1 0.00092 19.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMG45321.1 - 0.00071 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EMG45321.1 - 0.00095 19.4 0.4 0.0065 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EMG45321.1 - 0.0021 18.1 0.1 0.024 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMG45321.1 - 0.015 15.5 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EMG45321.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EMG45321.1 - 0.017 15.7 0.0 0.042 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EMG45321.1 - 0.018 14.4 0.1 0.49 9.7 0.1 2.3 1 1 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 EMG45321.1 - 0.018 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EMG45321.1 - 0.021 14.0 0.2 0.066 12.4 0.1 1.7 1 1 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 EMG45321.1 - 0.035 14.0 0.1 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 EMG45321.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EMG45321.1 - 0.055 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 EMG45321.1 - 0.058 13.1 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain NB-ARC PF00931.22 EMG45321.1 - 0.081 12.1 0.0 0.63 9.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 EMG45321.1 - 0.084 12.1 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EMG45321.1 - 0.094 12.6 0.2 0.61 10.0 0.1 2.1 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.6 EMG45321.1 - 0.094 12.4 0.3 0.29 10.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMG45321.1 - 0.1 12.2 0.1 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EMG45321.1 - 0.14 11.6 0.5 0.47 9.9 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein Peptidase_C48 PF02902.19 EMG45322.1 - 5.1e-24 85.3 4.4 1.2e-23 84.2 4.4 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain YqfQ PF14181.6 EMG45322.1 - 0.0046 17.2 0.1 0.0046 17.2 0.1 3.5 5 0 0 5 5 5 1 YqfQ-like protein DUF3450 PF11932.8 EMG45323.1 - 0.0037 16.6 9.9 0.0066 15.8 9.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HD_2 PF12917.7 EMG45323.1 - 0.015 15.1 3.0 0.015 15.1 3.0 1.8 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme TPR_MLP1_2 PF07926.12 EMG45323.1 - 0.097 12.7 17.1 0.088 12.9 14.7 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 EMG45323.1 - 0.61 9.1 14.6 1.4 7.9 14.6 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MCC-bdg_PDZ PF10506.9 EMG45323.1 - 0.74 9.9 6.0 3 7.9 4.8 2.7 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ZapB PF06005.12 EMG45323.1 - 1.7 9.2 17.6 4.4 7.8 7.4 3.0 1 1 1 2 2 2 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 EMG45323.1 - 3.6 8.2 12.4 8.6 7.0 6.3 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4349 PF14257.6 EMG45323.1 - 3.9 6.9 8.9 10 5.5 8.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) FAD_binding_3 PF01494.19 EMG45324.1 - 4.9e-19 68.8 0.0 8.6e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMG45324.1 - 1.6e-08 34.6 0.0 6.9e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMG45324.1 - 2.1e-05 24.6 0.0 4.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMG45324.1 - 5.1e-05 22.7 0.0 0.00031 20.1 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMG45324.1 - 5.5e-05 23.7 0.0 0.0007 20.1 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EMG45324.1 - 7.2e-05 22.0 0.0 0.0082 15.2 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase 3HCDH_N PF02737.18 EMG45324.1 - 0.00034 20.5 0.0 0.00055 19.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EMG45324.1 - 0.0073 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 EMG45324.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 EMG45324.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EMG45324.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LRR_4 PF12799.7 EMG45325.1 - 3.7e-09 36.7 30.8 0.0044 17.4 3.6 8.7 5 3 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMG45325.1 - 1.2e-08 34.3 9.7 3.3 8.0 0.0 8.1 8 1 0 8 8 8 4 Leucine Rich repeat LRR_8 PF13855.6 EMG45325.1 - 2.1e-07 30.6 14.4 0.015 15.0 0.2 6.0 6 1 1 7 7 7 3 Leucine rich repeat LRR_2 PF07723.13 EMG45325.1 - 0.046 14.4 2.1 3.3 8.5 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat TypeIII_RM_meth PF12564.8 EMG45325.1 - 0.05 13.7 0.2 2.4 8.3 0.1 2.5 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit LRR_9 PF14580.6 EMG45325.1 - 0.069 12.7 3.6 0.076 12.5 0.4 2.7 4 0 0 4 4 4 0 Leucine-rich repeat FNIP PF05725.12 EMG45325.1 - 2.2 8.5 12.2 26 5.1 0.2 6.1 6 1 0 6 6 6 0 FNIP Repeat PTS_2-RNA PF01885.16 EMG45326.1 - 6.3e-42 143.7 3.2 2.8e-36 125.2 1.0 2.3 1 1 1 2 2 2 2 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.17 EMG45326.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 La domain Utp8 PF10395.9 EMG45327.1 - 2e-206 687.7 28.1 2.3e-206 687.5 28.1 1.0 1 0 0 1 1 1 1 Utp8 family MOZ_SAS PF01853.18 EMG45328.1 - 3.1e-73 245.3 0.2 5e-73 244.6 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 EMG45328.1 - 3.7e-22 78.0 0.6 7.1e-22 77.0 0.6 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 EMG45328.1 - 1.8e-20 72.3 0.5 3.9e-20 71.2 0.5 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EMG45328.1 - 0.004 17.5 0.0 0.0083 16.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain WD40 PF00400.32 EMG45329.1 - 2.2e-42 142.2 11.2 1.1e-07 32.4 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG45329.1 - 1.8e-08 34.6 0.2 0.45 10.8 0.0 4.8 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EMG45329.1 - 2.3e-05 23.4 1.5 0.42 9.3 0.1 4.4 1 1 4 5 5 5 2 Nup133 N terminal like WD40_like PF17005.5 EMG45329.1 - 0.00091 18.6 0.0 0.018 14.4 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain BBS2_Mid PF14783.6 EMG45329.1 - 0.00092 19.2 0.1 2.6 8.1 0.0 3.1 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EMG45329.1 - 0.11 11.1 4.0 0.57 8.8 0.2 3.2 2 2 2 4 4 4 0 Nucleoporin Nup120/160 THB PF18362.1 EMG45330.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Tri-helix bundle domain WD40 PF00400.32 EMG45331.1 - 2.3e-40 135.8 14.9 6.5e-11 42.6 0.6 8.3 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG45331.1 - 4e-05 23.8 1.5 1.1 9.6 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMG45331.1 - 0.00014 20.6 1.1 0.0014 17.4 0.2 2.9 2 1 2 4 4 4 1 Nucleoporin Nup120/160 TPR_2 PF07719.17 EMG45332.1 - 2.6e-06 27.1 2.9 0.67 10.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMG45332.1 - 0.00029 20.5 7.1 0.36 10.7 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat LRR_4 PF12799.7 EMG45332.1 - 0.00086 19.7 25.9 1.1 9.7 0.2 6.7 4 2 1 6 6 6 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EMG45332.1 - 0.00094 19.0 0.1 0.0023 17.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like TPR_7 PF13176.6 EMG45332.1 - 0.037 14.0 0.2 0.22 11.6 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMG45332.1 - 0.044 14.4 1.8 0.14 12.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMG45332.1 - 0.082 13.2 0.2 9.5 6.6 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EMG45332.1 - 0.098 12.7 1.2 5.1 7.2 0.1 2.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EMG45332.1 - 0.2 11.9 7.6 5.6 7.4 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.6 EMG45332.1 - 0.22 11.6 6.3 2.9 8.2 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat U3_snoRNA_assoc PF08297.11 EMG45333.1 - 7.7e-19 68.2 6.3 7.7e-19 68.2 6.3 3.0 2 1 0 2 2 2 1 U3 snoRNA associated CDC45 PF02724.14 EMG45333.1 - 1.8 6.8 23.0 2.2 6.5 23.0 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 EMG45334.1 - 7e-32 110.7 30.0 7e-32 110.7 30.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG45334.1 - 9.5e-09 34.6 13.6 9.5e-09 34.6 13.6 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter AhpC-TSA PF00578.21 EMG45335.1 - 2.8e-22 78.9 0.0 4.3e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMG45335.1 - 7.9e-17 61.3 0.0 1.2e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EMG45335.1 - 0.0052 16.9 0.0 0.0072 16.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme RRN3 PF05327.11 EMG45335.1 - 8.1 4.9 8.8 10 4.6 8.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pkinase PF00069.25 EMG45336.1 - 1.2e-48 165.8 0.1 2.3e-43 148.5 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45336.1 - 2.9e-18 66.1 0.0 6.5e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMG45336.1 - 0.032 14.1 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ist1 PF03398.14 EMG45337.1 - 3.7e-59 199.3 3.9 4.5e-59 199.0 3.9 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF3336 PF11815.8 EMG45338.1 - 3.4e-32 111.0 7.1 3.4e-32 111.0 7.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EMG45338.1 - 1.1e-22 81.2 0.0 3e-22 79.8 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Lactamase_B_4 PF13691.6 EMG45339.1 - 3.5e-21 74.6 0.1 9.3e-21 73.3 0.1 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EMG45339.1 - 0.00012 21.7 0.1 0.34 10.4 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Abhydrolase_9_N PF15420.6 EMG45340.1 - 0.028 14.4 0.2 0.039 13.9 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Ribosomal_L2_C PF03947.18 EMG45341.1 - 6.6e-50 168.5 1.2 1.4e-49 167.5 1.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EMG45341.1 - 1e-24 86.3 1.0 1.9e-23 82.2 0.6 2.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain OSCP PF00213.18 EMG45342.1 - 3.3e-44 151.0 0.8 3.9e-44 150.8 0.8 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Metallophos PF00149.28 EMG45343.1 - 1.6e-05 25.5 13.8 6.4e-05 23.5 13.8 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AA_permease PF00324.21 EMG45344.1 - 2.3e-79 267.2 16.2 2.9e-79 266.9 16.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45344.1 - 3.4e-18 65.7 16.8 4e-18 65.5 16.8 1.0 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.32 EMG45345.1 - 4.7e-09 36.7 8.9 0.0081 17.0 0.2 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat PNP_UDP_1 PF01048.20 EMG45346.1 - 1.5e-37 129.1 0.0 1.7e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Tautomerase_2 PF14552.6 EMG45347.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme Colicin-DNase PF12639.7 EMG45347.1 - 0.35 11.7 2.5 4.7 8.1 0.5 2.6 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin DUF919 PF06034.11 EMG45347.1 - 1.8 8.5 6.3 0.35 10.7 0.9 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF5633 PF18656.1 EMG45347.1 - 2.2 8.2 8.4 3.3 7.7 2.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5633) DAGAT PF03982.13 EMG45348.1 - 6e-58 196.1 7.8 2e-27 95.9 0.0 5.1 4 1 0 4 4 4 4 Diacylglycerol acyltransferase Tmemb_185A PF10269.9 EMG45348.1 - 0.027 14.2 1.3 0.063 13.0 1.3 1.4 1 1 0 1 1 1 0 Transmembrane Fragile-X-F protein ORC3_N PF07034.11 EMG45349.1 - 2.6e-20 72.8 2.3 2.4e-14 53.2 0.2 2.2 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus DUF1803 PF08820.10 EMG45349.1 - 0.0055 16.7 0.1 0.025 14.6 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1803) DHO_dh PF01180.21 EMG45349.1 - 0.006 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ER PF01133.17 EMG45349.1 - 0.019 15.0 2.4 0.095 12.7 0.1 3.0 2 2 0 2 2 2 0 Enhancer of rudimentary Neur_chan_memb PF02932.16 EMG45350.1 - 0.064 13.3 1.5 0.082 13.0 1.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.11 EMG45350.1 - 0.76 9.8 24.4 0.94 9.5 24.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FixO PF02433.15 EMG45350.1 - 5 6.5 7.3 1.3 8.4 3.9 1.7 1 1 1 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF4407 PF14362.6 EMG45350.1 - 6.6 6.0 13.7 9.6 5.5 13.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KdpC PF02669.15 EMG45350.1 - 7.9 6.3 6.4 3.8 7.3 2.8 2.5 1 1 1 2 2 2 0 K+-transporting ATPase, c chain Mannosyl_trans3 PF11051.8 EMG45351.1 - 7e-74 248.6 0.6 7e-74 248.6 0.6 1.7 2 0 0 2 2 2 1 Mannosyltransferase putative GBP_C PF02841.14 EMG45351.1 - 0.15 11.4 1.1 0.26 10.7 1.1 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Gpr1_Fun34_YaaH PF01184.19 EMG45352.1 - 9.3e-74 247.5 18.5 1.1e-73 247.3 18.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Aminotran_4 PF01063.19 EMG45353.1 - 4.9e-37 127.9 0.0 6.5e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV AA_permease PF00324.21 EMG45354.1 - 2e-49 168.5 24.9 2.3e-49 168.3 24.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45354.1 - 1.1e-14 54.2 21.6 1.3e-14 53.9 21.6 1.0 1 0 0 1 1 1 1 Amino acid permease Orai-1 PF07856.12 EMG45354.1 - 0.19 11.4 11.1 0.39 10.4 11.0 1.6 1 1 0 1 1 1 0 Mediator of CRAC channel activity LRR_8 PF13855.6 EMG45355.1 - 6.4e-08 32.2 8.4 6.4e-08 32.2 8.4 6.5 6 2 0 6 6 6 2 Leucine rich repeat LRR_4 PF12799.7 EMG45355.1 - 7.6e-08 32.5 43.5 0.11 13.0 4.7 10.1 9 4 0 10 10 10 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EMG45355.1 - 0.24 10.9 4.0 1.5 8.3 1.2 2.9 2 0 0 2 2 2 0 Leucine-rich repeat F-box-like PF12937.7 EMG45355.1 - 0.26 11.2 1.0 0.82 9.6 1.0 1.9 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.33 EMG45355.1 - 1.5 9.7 28.7 32 5.6 0.0 9.0 6 3 0 6 6 6 0 Leucine Rich Repeat NIF PF03031.18 EMG45356.1 - 4.3e-53 179.3 0.2 8.3e-53 178.3 0.2 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1507 PF07408.11 EMG45357.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) CLP1_P PF16575.5 EMG45358.1 - 5.3e-26 91.6 0.1 9.7e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EMG45358.1 - 2e-23 82.4 0.0 3.8e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 EMG45358.1 - 0.00019 21.8 0.0 0.00041 20.8 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP-synt_ab PF00006.25 EMG45358.1 - 0.0087 15.7 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 EMG45358.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 EMG45358.1 - 0.23 11.7 0.1 0.52 10.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain PTPA PF03095.15 EMG45359.1 - 8.2e-118 393.2 0.1 9.6e-118 393.0 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MMR_HSR1_Xtn PF16897.5 EMG45359.1 - 0.016 15.2 0.4 0.06 13.4 0.2 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain LETM1 PF07766.13 EMG45360.1 - 0.00042 19.7 3.3 0.19 11.1 0.2 2.2 2 0 0 2 2 2 2 LETM1-like protein Pox_I1 PF03289.13 EMG45360.1 - 0.027 13.6 2.0 0.076 12.1 0.4 2.0 1 1 1 2 2 2 0 Poxvirus protein I1 Pkinase PF00069.25 EMG45361.1 - 3.7e-77 259.3 0.0 5.4e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45361.1 - 3.7e-39 134.6 0.0 5.5e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EMG45361.1 - 2.8e-28 98.0 0.4 9.4e-17 61.1 0.1 2.8 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 EMG45361.1 - 2e-13 50.4 0.0 2.3e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 EMG45361.1 - 3e-07 30.0 0.0 7.8e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FHA_2 PF17913.1 EMG45361.1 - 1.5e-06 28.3 0.0 0.0067 16.6 0.0 2.8 2 0 0 2 2 2 2 FHA domain Kdo PF06293.14 EMG45361.1 - 2.9e-05 23.5 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMG45361.1 - 0.0027 17.7 0.0 0.022 14.7 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EMG45361.1 - 0.007 16.0 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family XisI PF08869.11 EMG45361.1 - 0.12 12.8 0.2 4.5 7.7 0.1 2.7 2 0 0 2 2 2 0 XisI protein PTR2 PF00854.21 EMG45362.1 - 1.1e-93 314.2 12.5 5.4e-93 311.9 12.5 1.8 1 1 0 1 1 1 1 POT family PTR2 PF00854.21 EMG45363.1 - 4.9e-93 312.1 12.5 1.7e-92 310.3 12.5 1.7 1 1 0 1 1 1 1 POT family zf-C2H2 PF00096.26 EMG45364.1 - 8.9e-07 29.0 9.3 0.0026 18.1 0.0 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EMG45364.1 - 0.1 12.9 0.1 0.1 12.9 0.1 3.1 2 1 0 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 EMG45364.1 - 0.12 13.2 20.7 0.17 12.8 0.1 4.3 5 0 0 5 5 5 0 C2H2-type zinc finger CAF-1_p60_C PF15512.6 EMG45364.1 - 0.15 12.6 0.1 0.26 11.8 0.1 1.4 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal Fer4_22 PF17179.4 EMG45364.1 - 0.51 11.2 6.8 0.18 12.7 2.1 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain zf_C2H2_ZHX PF18387.1 EMG45364.1 - 0.83 9.3 6.8 9.2 6.0 0.0 3.5 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain AA_permease PF00324.21 EMG45365.1 - 9.5e-80 268.5 13.0 1.2e-79 268.2 13.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45365.1 - 3.7e-18 65.6 14.0 4.3e-18 65.3 14.0 1.0 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 EMG45365.1 - 0.032 14.7 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 Pet100 Yip1 PF04893.17 EMG45365.1 - 0.12 12.0 15.4 0.023 14.4 6.8 2.2 1 1 1 2 2 2 0 Yip1 domain WD40 PF00400.32 EMG45366.1 - 4.7e-09 36.7 8.9 0.0081 17.0 0.2 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat RabGAP-TBC PF00566.18 EMG45367.1 - 1.4e-34 119.7 8.1 1.4e-34 119.7 8.1 1.9 3 0 0 3 3 3 1 Rab-GTPase-TBC domain PKcGMP_CC PF16808.5 EMG45367.1 - 1.1 9.2 4.8 0.86 9.5 0.6 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Dynamin_M PF01031.20 EMG45368.1 - 2.5e-109 364.9 0.3 6e-109 363.7 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EMG45368.1 - 2.2e-54 184.0 0.0 2.2e-54 184.0 0.0 2.5 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EMG45368.1 - 5.2e-31 106.7 4.8 1.3e-30 105.4 4.8 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EMG45368.1 - 0.00026 21.0 0.4 0.004 17.2 0.4 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMG45368.1 - 0.0078 15.8 0.4 1.7 8.2 0.1 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B Ribophorin_I PF04597.14 EMG45369.1 - 5.4e-119 398.3 5.1 6.3e-119 398.0 5.1 1.0 1 0 0 1 1 1 1 Ribophorin I Alginate_lyase2 PF08787.11 EMG45369.1 - 0.18 11.6 1.7 0.33 10.8 1.7 1.3 1 0 0 1 1 1 0 Alginate lyase Pro_isomerase PF00160.21 EMG45370.1 - 2.4e-31 109.1 0.2 3.9e-31 108.5 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF5305 PF17231.2 EMG45370.1 - 0.03 13.7 0.1 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Proteasome PF00227.26 EMG45371.1 - 9.4e-46 155.7 0.9 1.1e-45 155.5 0.9 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 EMG45371.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Phage late-transcription coactivator AA_permease PF00324.21 EMG45372.1 - 8.3e-47 159.9 24.4 9.4e-47 159.7 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45372.1 - 9.5e-14 51.1 21.2 1.1e-13 50.8 21.2 1.0 1 0 0 1 1 1 1 Amino acid permease Orai-1 PF07856.12 EMG45372.1 - 6.4 6.4 9.6 15 5.2 9.6 1.6 1 1 0 1 1 1 0 Mediator of CRAC channel activity Asp PF00026.23 EMG45373.1 - 2.2e-66 224.4 6.0 2.2e-66 224.4 6.0 2.1 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMG45373.1 - 2.3e-07 31.2 5.7 5.9e-06 26.6 0.1 3.9 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMG45373.1 - 4e-05 24.2 0.2 1.3 9.7 0.0 3.7 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 EMG45373.1 - 0.037 13.8 0.0 0.42 10.4 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal IMUP PF15761.5 EMG45373.1 - 1.3 9.7 12.4 3.5 8.3 12.4 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein CDK2AP PF09806.9 EMG45373.1 - 6 6.9 9.0 1.1 9.3 4.6 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Myosin_head PF00063.21 EMG45376.1 - 5.8e-277 920.4 8.7 5.8e-277 920.4 8.7 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 EMG45376.1 - 2.7e-25 88.6 0.3 2.7e-25 88.6 0.3 3.2 3 0 0 3 3 2 1 DIL domain IQ PF00612.27 EMG45376.1 - 3.2e-15 54.4 31.8 4.2e-05 23.0 0.4 7.1 7 0 0 7 7 7 5 IQ calmodulin-binding motif SKA2 PF16740.5 EMG45376.1 - 0.00094 18.9 14.4 0.0066 16.2 6.9 3.6 3 0 0 3 3 3 2 Spindle and kinetochore-associated protein 2 AAA_22 PF13401.6 EMG45376.1 - 0.0062 16.8 0.2 0.051 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.19 EMG45376.1 - 0.011 15.6 0.6 0.011 15.6 0.6 2.1 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 EMG45376.1 - 0.085 13.2 2.1 0.15 12.4 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain IFT57 PF10498.9 EMG45376.1 - 0.21 10.5 31.6 0.0085 15.1 24.9 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Tup_N PF08581.10 EMG45376.1 - 1.7 9.0 24.7 0.2 12.0 11.8 4.5 2 1 2 4 4 4 0 Tup N-terminal LPP PF04728.13 EMG45376.1 - 4.9 7.6 9.3 12 6.4 0.2 4.1 3 1 1 4 4 3 0 Lipoprotein leucine-zipper IFP_35_N PF07334.13 EMG45376.1 - 5.3 7.2 9.3 1.5 9.0 3.9 3.0 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus BolA PF01722.18 EMG45377.1 - 7.8e-29 99.8 1.3 1e-28 99.4 1.3 1.2 1 0 0 1 1 1 1 BolA-like protein KAR9 PF08580.10 EMG45378.1 - 3.2e-189 630.8 29.3 1.3e-177 592.4 24.3 2.0 1 1 1 2 2 2 2 Yeast cortical protein KAR9 PGM_PMM_I PF02878.16 EMG45380.1 - 6e-18 64.9 0.0 6.1e-09 35.7 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EMG45380.1 - 8.5e-07 29.5 0.1 1.2e-05 25.9 0.0 2.8 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EMG45380.1 - 0.0028 17.8 0.0 0.008 16.4 0.0 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SNase PF00565.17 EMG45381.1 - 5.1e-23 81.6 0.2 6.8e-23 81.2 0.2 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ERG2_Sigma1R PF04622.12 EMG45382.1 - 9.6e-88 293.0 0.1 1.1e-87 292.8 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein MFS_1 PF07690.16 EMG45384.1 - 1.5e-31 109.6 67.1 8.5e-25 87.4 43.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG45384.1 - 0.00099 18.1 39.0 0.033 13.1 14.3 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter UPF0239 PF06783.11 EMG45384.1 - 0.13 12.5 0.2 0.29 11.4 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) MFS_1_like PF12832.7 EMG45384.1 - 0.17 10.7 19.1 0.04 12.8 8.2 3.1 2 1 0 2 2 2 0 MFS_1 like family PUA PF01472.20 EMG45385.1 - 0.11 12.5 8.6 1.7 8.6 0.1 4.1 5 0 0 5 5 5 0 PUA domain gpW PF02831.15 EMG45385.1 - 0.37 10.7 1.6 16 5.5 0.0 3.5 3 1 1 4 4 4 0 gpW Lipid_bd PF12888.7 EMG45385.1 - 1.6 9.2 15.6 9.7 6.7 0.4 4.6 1 1 4 5 5 5 0 Lipid-binding putative hydrolase DUF3921 PF13060.6 EMG45385.1 - 7.8 6.6 14.4 17 5.6 0.2 5.0 4 1 2 6 6 6 0 Protein of unknown function (DUF3921) Pkinase PF00069.25 EMG45387.1 - 1.4e-50 172.2 0.0 2.6e-50 171.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45387.1 - 6.9e-20 71.4 0.0 1.9e-19 70.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG45387.1 - 0.00055 19.3 0.0 0.041 13.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EMG45387.1 - 0.013 15.1 1.9 4 7.0 0.0 2.8 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EMG45387.1 - 0.041 13.8 0.0 1.5 8.7 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EMG45387.1 - 0.056 12.2 3.2 1.2 7.8 0.0 3.0 3 1 0 3 3 3 0 Fungal protein kinase LMBR1 PF04791.16 EMG45387.1 - 0.27 10.1 4.8 0.39 9.6 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pinin_SDK_memA PF04696.13 EMG45387.1 - 0.55 10.3 10.2 0.033 14.2 3.2 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Actin PF00022.19 EMG45388.1 - 2.6e-111 372.1 0.0 1.5e-110 369.6 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EMG45388.1 - 0.0024 16.8 0.0 0.0071 15.2 0.0 1.6 1 1 0 1 1 1 1 MreB/Mbl protein Actin_micro PF17003.5 EMG45388.1 - 0.24 10.5 0.1 1.8 7.7 0.0 2.0 2 0 0 2 2 2 0 Putative actin-like family GCD14 PF08704.10 EMG45389.1 - 7.9e-81 271.3 0.0 1.1e-80 270.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EMG45389.1 - 0.0019 18.0 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.6 EMG45389.1 - 0.0025 17.6 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Ubie_methyltran PF01209.18 EMG45389.1 - 0.07 12.5 0.0 0.39 10.0 0.0 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EMG45389.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EMG45389.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase LSM PF01423.22 EMG45390.1 - 3e-14 52.5 0.1 4.6e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 LSM domain Acyl-CoA_dh_1 PF00441.24 EMG45391.1 - 6.3e-24 84.9 0.2 9.2e-24 84.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMG45391.1 - 3.9e-13 49.4 0.0 4.2e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EMG45391.1 - 1.2e-11 45.3 0.0 2.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMG45391.1 - 2e-06 28.1 0.0 3.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RPN7 PF10602.9 EMG45392.1 - 7.9e-55 185.2 1.6 1.8e-54 184.1 1.6 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EMG45392.1 - 9.8e-16 58.2 1.7 1.6e-15 57.5 0.4 2.1 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 EMG45392.1 - 0.00062 19.8 0.3 0.0016 18.5 0.0 1.8 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family KIX_2 PF16987.5 EMG45392.1 - 0.042 13.8 0.6 0.15 12.1 0.3 2.1 1 1 0 1 1 1 0 KIX domain Cnl2_NKP2 PF09447.10 EMG45392.1 - 0.16 12.1 2.3 1.8 8.8 2.3 2.7 1 1 0 1 1 1 0 Cnl2/NKP2 family protein DASH_Duo1 PF08651.10 EMG45392.1 - 4.3 7.2 7.6 1.2 8.9 0.1 3.1 4 0 0 4 4 4 0 DASH complex subunit Duo1 CSTF2_hinge PF14327.6 EMG45393.1 - 2.7e-22 79.0 1.0 2.7e-22 79.0 1.0 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EMG45393.1 - 1.9e-07 30.8 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.19 EMG45393.1 - 1.7 8.5 7.7 1.9 8.4 7.7 1.1 1 0 0 1 1 1 0 SPX domain zf-RING_2 PF13639.6 EMG45394.1 - 7.3e-10 39.0 1.8 1.6e-07 31.6 0.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 EMG45394.1 - 2.4e-09 37.3 1.8 2.2e-08 34.3 0.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EMG45394.1 - 1.1e-07 31.5 1.6 1e-05 25.3 0.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMG45394.1 - 1.1e-06 28.4 2.2 2.5e-05 24.1 0.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG45394.1 - 5e-06 26.4 1.0 0.012 15.6 0.1 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-ANAPC11 PF12861.7 EMG45394.1 - 8.3e-05 22.6 0.2 0.00044 20.3 0.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EMG45394.1 - 0.00035 20.3 2.2 0.00072 19.4 0.5 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EMG45394.1 - 0.0006 19.5 1.1 0.24 11.2 0.1 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_5 PF14634.6 EMG45394.1 - 0.00068 19.6 0.9 0.022 14.7 0.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EMG45394.1 - 0.0013 18.6 3.1 0.0092 15.8 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMG45394.1 - 0.054 13.7 1.4 0.054 13.7 1.4 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EMG45394.1 - 0.35 11.1 1.6 13 6.0 0.6 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain TraG-D_C PF12696.7 EMG45394.1 - 0.67 10.0 5.1 1.5 8.8 5.1 1.6 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG zf-Nse PF11789.8 EMG45394.1 - 0.73 9.7 3.0 1.3 8.9 1.4 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Menin PF05053.13 EMG45394.1 - 0.77 8.0 4.8 1.1 7.5 4.8 1.2 1 0 0 1 1 1 0 Menin Chitin_synth_1 PF01644.17 EMG45395.1 - 2.1e-70 235.9 0.3 3.5e-70 235.2 0.3 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 EMG45395.1 - 9.7e-24 83.9 4.7 3.9e-15 55.5 0.1 3.1 2 1 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 EMG45395.1 - 4e-23 81.2 0.0 1.1e-22 79.8 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 EMG45395.1 - 9.3e-10 38.7 1.2 9.3e-10 38.7 1.2 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EMG45395.1 - 0.11 12.3 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 EZH2_N PF18601.1 EMG45395.1 - 0.12 12.8 0.3 0.27 11.6 0.3 1.5 1 0 0 1 1 1 0 EZH2 N-terminal domain MFS_1 PF07690.16 EMG45397.1 - 1.5e-35 122.8 37.2 1.5e-35 122.8 37.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Glu-tRNAGln PF02686.15 EMG45398.1 - 0.00049 20.3 0.1 0.0018 18.5 0.0 1.9 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit FAM176 PF14851.6 EMG45398.1 - 0.079 12.6 1.1 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 FAM176 family DUF4642 PF15484.6 EMG45398.1 - 0.08 13.2 0.5 0.21 11.8 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) Pam16 PF03656.13 EMG45398.1 - 0.097 12.7 0.8 0.78 9.8 0.0 2.6 3 0 0 3 3 3 0 Pam16 PBP1_TM PF14812.6 EMG45398.1 - 0.18 12.2 4.9 0.58 10.6 4.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Band_7 PF01145.25 EMG45399.1 - 8.1e-32 110.7 0.7 1.1e-31 110.2 0.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EMG45399.1 - 0.00092 19.0 0.4 0.0014 18.4 0.4 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family DUF5344 PF17279.2 EMG45399.1 - 0.051 14.2 0.4 1.2 9.7 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Latrotoxin_C PF15658.6 EMG45399.1 - 0.06 13.1 0.7 0.14 11.9 0.3 1.8 1 1 1 2 2 2 0 Latrotoxin C-terminal domain Cys_Met_Meta_PP PF01053.20 EMG45400.1 - 1.7e-61 207.9 0.0 3.9e-61 206.7 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMG45400.1 - 0.0033 16.4 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Uma2 PF05685.12 EMG45400.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative restriction endonuclease BCDHK_Adom3 PF10436.9 EMG45401.1 - 3e-67 225.5 0.1 4.8e-67 224.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EMG45401.1 - 1.4e-11 44.9 0.0 7.5e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMG45401.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peroxin-13_N PF04088.13 EMG45402.1 - 1.5e-34 119.4 2.9 1.5e-34 119.4 2.9 1.8 2 0 0 2 2 2 1 Peroxin 13, N-terminal region SH3_9 PF14604.6 EMG45402.1 - 6.8e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMG45402.1 - 3.2e-07 29.8 0.0 5.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMG45402.1 - 1.7e-06 27.6 0.0 3.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 EMG45402.1 - 6.8e-05 23.1 0.1 0.00015 22.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Sm_multidrug_ex PF06695.11 EMG45402.1 - 0.019 15.6 0.1 0.034 14.8 0.1 1.4 1 0 0 1 1 1 0 Putative small multi-drug export protein SH3_4 PF06347.13 EMG45402.1 - 0.03 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain DUF3169 PF11368.8 EMG45402.1 - 0.17 11.4 2.6 9.1 5.7 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF4271 PF14093.6 EMG45402.1 - 1.4 8.8 4.0 2.5 7.9 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) RVT_2 PF07727.14 EMG45403.1 - 1.3e-31 110.1 0.0 1.9e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CN_hydrolase PF00795.22 EMG45404.1 - 6e-46 156.9 0.0 6.7e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AAA PF00004.29 EMG45404.1 - 0.049 14.1 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hyr1 PF15789.5 EMG45406.1 - 6.9e-30 102.3 83.0 2.7e-09 36.4 13.2 4.2 4 0 0 4 4 4 4 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG45406.1 - 0.0052 17.2 19.8 0.87 10.1 1.1 3.8 1 1 3 4 4 4 3 Family of unknown function (DUF5628) Pput2613-deam PF14427.6 EMG45406.1 - 0.15 12.0 11.2 0.57 10.1 0.7 3.1 2 1 2 4 4 4 0 Pput_2613-like deaminase Hyphal_reg_CWP PF11765.8 EMG45407.1 - 4.1e-94 315.2 14.0 4.8e-94 315.0 14.0 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 EMG45407.1 - 2.9e-08 33.1 28.1 6.9e-06 25.5 6.1 3.1 3 0 0 3 3 3 2 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG45407.1 - 9.5 6.7 8.0 4.4 7.8 0.6 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5628) Pribosyltran_N PF13793.6 EMG45409.1 - 3.5e-41 139.8 0.0 2.4e-40 137.1 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EMG45409.1 - 4.7e-39 134.3 2.8 1.1e-36 126.6 2.8 2.3 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EMG45409.1 - 8.9e-09 35.1 0.5 1e-07 31.6 0.5 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PNP_UDP_1 PF01048.20 EMG45409.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily Rpn9_C PF18261.1 EMG45409.1 - 0.091 12.4 0.2 0.24 11.0 0.2 1.7 1 0 0 1 1 1 0 Rpn9 C-terminal helix Sirohm_synth_M PF14824.6 EMG45409.1 - 0.17 11.4 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central HSF_DNA-bind PF00447.17 EMG45410.1 - 4e-29 101.1 3.4 7.2e-29 100.3 3.4 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 EMG45410.1 - 5.4e-26 91.0 0.2 1.6e-25 89.5 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HALZ PF02183.18 EMG45410.1 - 0.0076 16.5 0.8 0.013 15.7 0.8 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Spermine_synth PF01564.17 EMG45410.1 - 0.013 15.0 0.5 0.03 13.7 0.2 1.8 2 0 0 2 2 2 0 Spermine/spermidine synthase domain betaPIX_CC PF16523.5 EMG45410.1 - 0.099 12.5 0.6 0.21 11.5 0.2 1.7 2 0 0 2 2 2 0 betaPIX coiled coil TMF_DNA_bd PF12329.8 EMG45410.1 - 0.11 12.6 0.7 0.23 11.5 0.7 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 EMG45410.1 - 0.3 11.2 0.9 0.56 10.3 0.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor ATG16 PF08614.11 EMG45410.1 - 0.82 9.9 5.9 0.26 11.5 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 EMG45410.1 - 1.6 9.2 7.4 0.11 13.0 1.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 EMG45410.1 - 7 6.5 7.6 0.14 11.9 0.4 1.9 2 0 0 2 2 2 0 Septum formation initiator Spt20 PF12090.8 EMG45410.1 - 9.1 5.8 14.4 30 4.1 9.7 2.3 2 0 0 2 2 2 0 Spt20 family Glyco_hydro_31 PF01055.26 EMG45411.1 - 2.7e-139 465.2 2.9 3.8e-139 464.7 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EMG45411.1 - 7.4e-23 80.7 0.7 9e-21 74.0 0.1 3.0 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EMG45411.1 - 0.0059 16.9 0.0 0.02 15.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Lectin_C PF00059.21 EMG45411.1 - 0.036 14.8 0.5 0.57 10.9 0.1 2.5 2 0 0 2 2 2 0 Lectin C-type domain GIY-YIG PF01541.24 EMG45412.1 - 4.4e-14 52.5 0.0 7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.9 EMG45412.1 - 0.005 17.4 0.1 0.011 16.3 0.1 1.6 1 1 0 1 1 1 1 T5orf172 domain BRE1 PF08647.11 EMG45413.1 - 3.1e-21 75.3 16.0 3.1e-21 75.3 16.0 7.0 4 3 1 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.6 EMG45413.1 - 1e-07 31.7 8.0 1.8e-07 30.9 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMG45413.1 - 2e-07 30.7 6.9 3.2e-07 30.1 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMG45413.1 - 6e-07 29.2 6.3 1e-06 28.4 6.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EMG45413.1 - 2.7e-06 27.2 8.2 5e-06 26.3 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMG45413.1 - 5.7e-06 26.2 9.3 9.6e-06 25.5 9.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EMG45413.1 - 2.8e-05 24.3 8.7 4.7e-05 23.6 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EMG45413.1 - 0.00046 20.1 6.9 0.001 19.1 6.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EMG45413.1 - 0.041 14.0 6.2 0.082 13.1 6.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Flagellin_D3 PF08884.11 EMG45413.1 - 0.049 14.0 0.1 0.17 12.3 0.1 1.9 1 0 0 1 1 1 0 Flagellin D3 domain Myb_DNA-bind_3 PF12776.7 EMG45413.1 - 0.064 14.2 0.6 0.064 14.2 0.6 4.8 5 2 2 8 8 6 0 Myb/SANT-like DNA-binding domain zf-rbx1 PF12678.7 EMG45413.1 - 0.083 13.2 6.1 0.18 12.1 6.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Gin PF10764.9 EMG45413.1 - 0.094 12.7 2.0 0.26 11.3 2.0 1.8 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin DUF1272 PF06906.11 EMG45413.1 - 0.12 12.5 4.5 0.22 11.6 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.6 EMG45413.1 - 0.21 11.5 3.3 0.46 10.4 3.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.26 EMG45413.1 - 0.35 11.4 0.0 0.35 11.4 0.0 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-RING_10 PF16685.5 EMG45413.1 - 0.44 10.7 5.1 1.3 9.2 5.1 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 EMG45413.1 - 0.6 10.2 5.6 1.3 9.1 5.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.6 EMG45413.1 - 0.99 9.3 6.1 1.9 8.3 6.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1192 PF06698.11 EMG45413.1 - 1.1 9.4 15.9 0.098 12.7 0.6 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF1192) FYVE PF01363.21 EMG45413.1 - 4 7.6 10.6 35 4.6 10.6 2.3 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_4 PF13894.6 EMG45413.1 - 6.2 7.9 8.6 3.8 8.6 0.0 3.3 2 1 1 3 3 3 0 C2H2-type zinc finger HypA PF01155.19 EMG45413.1 - 7.6 6.6 11.9 1.4e+02 2.5 11.9 3.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Bromodomain PF00439.25 EMG45414.1 - 2e-39 133.5 4.4 4.3e-20 71.6 0.3 2.8 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EMG45414.1 - 4e-16 58.9 2.7 4e-16 58.9 2.7 2.8 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation SAT PF16073.5 EMG45415.1 - 9.8e-39 133.5 0.0 1.5e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 EMG45415.1 - 4.3e-30 104.4 0.0 7.9e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta His_Phos_2 PF00328.22 EMG45416.1 - 1.4e-136 455.8 0.1 1.8e-136 455.5 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EMG45416.1 - 6.3e-36 122.4 0.0 1.5e-35 121.2 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EMG45416.1 - 1.9e-07 30.8 0.0 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF1729 PF08354.10 EMG45417.1 - 1e-135 452.2 0.0 1.5e-135 451.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EMG45417.1 - 6.7e-94 315.0 0.0 3.6e-93 312.5 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain FAS_meander PF17951.1 EMG45417.1 - 1.8e-44 151.1 0.0 3.8e-44 150.0 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 EMG45417.1 - 7.1e-42 141.9 0.1 1.8e-41 140.6 0.1 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EMG45417.1 - 6.3e-16 58.7 0.0 1.6e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Arm PF00514.23 EMG45418.1 - 1.9e-86 281.8 17.3 4.8e-11 42.3 0.1 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EMG45418.1 - 5.1e-25 87.7 6.8 5.1e-25 87.7 6.8 2.7 3 0 0 3 3 3 1 Importin beta binding domain HEAT_EZ PF13513.6 EMG45418.1 - 1.4e-23 82.9 1.7 4.6e-06 27.0 0.1 6.3 4 2 2 6 6 6 6 HEAT-like repeat Arm_3 PF16186.5 EMG45418.1 - 2e-23 81.7 4.3 4.5e-23 80.6 4.3 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 EMG45418.1 - 5.9e-15 54.1 0.1 0.051 13.8 0.0 7.3 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 EMG45418.1 - 1e-14 54.7 0.2 0.0003 21.1 0.0 5.3 1 1 2 5 5 5 3 HEAT repeats V-ATPase_H_C PF11698.8 EMG45418.1 - 7.4e-08 32.5 0.2 0.38 10.9 0.0 4.4 4 0 0 4 4 4 2 V-ATPase subunit H Arm_2 PF04826.13 EMG45418.1 - 2.7e-06 27.0 0.5 0.73 9.2 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 EMG45418.1 - 1.2e-05 24.0 0.7 0.0022 16.6 0.1 2.8 1 1 2 3 3 3 3 Adaptin N terminal region NopRA1 PF16201.5 EMG45418.1 - 1.5e-05 24.7 0.0 0.12 12.0 0.0 3.9 2 2 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 EMG45418.1 - 1.7e-05 25.0 2.2 0.42 10.9 0.0 5.0 4 2 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.9 EMG45418.1 - 0.0001 22.2 0.1 1.3 9.1 0.0 4.2 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 EMG45418.1 - 0.24 11.3 1.0 4.8 7.1 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) Usp PF00582.26 EMG45419.1 - 7.9e-10 39.4 0.0 1.3e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family Glyco_trans_A_1 PF09318.10 EMG45419.1 - 0.026 14.2 2.2 0.12 12.1 0.8 2.4 1 1 1 2 2 2 0 Glycosyl transferase 1 domain A ADK PF00406.22 EMG45419.1 - 0.13 12.4 0.3 0.24 11.5 0.3 1.4 1 0 0 1 1 1 0 Adenylate kinase TGS PF02824.21 EMG45420.1 - 1e-11 44.7 0.0 1.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 TGS domain Ribosomal_L14 PF00238.19 EMG45421.1 - 4e-50 169.0 1.3 4.5e-50 168.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Paramyxo_P_V_N PF13825.6 EMG45421.1 - 0.013 15.0 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus PAS_3 PF08447.12 EMG45421.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold UPF0029 PF01205.19 EMG45422.1 - 6e-29 100.5 0.0 7.1e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RE_BstXI PF09552.10 EMG45422.1 - 0.046 12.9 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease Hyr1 PF15789.5 EMG45423.1 - 8.7e-06 25.2 31.9 0.00052 19.5 8.9 3.2 2 2 1 3 3 3 2 Hyphally regulated cell wall GPI-anchored protein 1 Peptidase_C25_C PF03785.14 EMG45423.1 - 0.11 12.3 5.0 0.083 12.7 1.6 2.0 1 1 1 2 2 2 0 Peptidase family C25, C terminal ig-like domain Thiamine_BP PF01910.17 EMG45425.1 - 1.4e-19 69.7 0.0 1.6e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Prok-E2_E PF14462.6 EMG45426.1 - 2.3 8.0 10.8 0.64 9.8 6.3 2.4 2 1 1 3 3 3 0 Prokaryotic E2 family E Gp_dh_C PF02800.20 EMG45427.1 - 3e-70 234.9 0.0 4.3e-70 234.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EMG45427.1 - 6.6e-41 138.7 0.1 1.2e-40 137.9 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EMG45427.1 - 0.0056 16.8 0.6 0.013 15.6 0.2 1.9 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EMG45427.1 - 0.048 13.0 0.1 0.092 12.1 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OstA PF03968.14 EMG45427.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 OstA-like protein ThiF PF00899.21 EMG45428.1 - 1.5e-106 355.2 0.0 1.7e-75 253.5 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EMG45428.1 - 3.5e-90 302.3 0.2 6.2e-90 301.5 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EMG45428.1 - 2.7e-36 124.1 0.0 6.7e-36 122.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 EMG45428.1 - 4.8e-28 97.2 0.2 1e-27 96.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EMG45428.1 - 1.5e-25 89.2 1.3 9.2e-25 86.6 1.9 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Hexapep_2 PF14602.6 EMG45428.1 - 2.8e-10 39.8 11.9 8.3e-09 35.0 6.5 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EMG45428.1 - 1.7e-08 33.8 12.0 3.6e-08 32.8 5.5 2.8 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EMG45428.1 - 8.4e-06 25.9 0.2 3.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Maltose acetyltransferase TBPIP_N PF15517.6 EMG45428.1 - 0.097 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 TBP-interacting protein N-terminus CENP-L PF13092.6 EMG45429.1 - 0.037 14.2 0.0 1.6 8.9 0.0 2.5 1 1 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 PMT PF02366.18 EMG45430.1 - 1.2e-95 319.7 17.3 1.2e-95 319.7 17.3 2.6 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EMG45430.1 - 8.4e-59 198.5 14.9 8.4e-59 198.5 14.9 2.6 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EMG45430.1 - 3.7e-27 95.4 0.1 6.5e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 MIR domain Fe-S_biosyn PF01521.20 EMG45431.1 - 1.7e-15 57.2 0.1 2.4e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis HEAT PF02985.22 EMG45432.1 - 7.7e-39 128.4 11.1 0.005 17.0 0.0 13.1 13 0 0 13 13 13 8 HEAT repeat HEAT_2 PF13646.6 EMG45432.1 - 4.9e-29 100.6 0.1 4.7e-10 39.7 0.0 7.9 3 3 3 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.7 EMG45432.1 - 1.5e-08 35.1 5.9 0.0026 18.3 0.0 7.5 5 2 5 10 10 10 2 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EMG45432.1 - 0.0019 18.4 6.2 0.37 11.0 0.2 5.4 4 3 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 EMG45432.1 - 0.0035 17.6 0.1 3.3 8.1 0.0 3.8 2 1 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain RIX1 PF08167.12 EMG45432.1 - 0.011 15.5 6.5 0.42 10.3 0.1 4.2 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 EMG45432.1 - 0.025 15.1 8.8 14 6.3 0.0 6.8 8 1 1 9 9 8 0 HEAT-like repeat Trp_Tyr_perm PF03222.13 EMG45432.1 - 0.034 13.2 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Importin_rep_4 PF18808.1 EMG45432.1 - 0.044 14.1 0.3 14 6.0 0.0 3.8 3 0 0 3 3 3 0 Importin repeat T4_Rnl2_C PF18043.1 EMG45432.1 - 0.06 13.5 1.3 0.39 10.9 0.0 3.1 4 0 0 4 4 4 0 T4 RNA ligase 2 C-terminal API5 PF05918.11 EMG45432.1 - 0.21 10.4 6.7 0.93 8.2 0.1 3.7 2 2 3 5 5 5 0 Apoptosis inhibitory protein 5 (API5) V-ATPase_H_C PF11698.8 EMG45432.1 - 0.38 10.9 3.5 3.3 7.8 0.2 3.4 3 2 2 5 5 5 0 V-ATPase subunit H M11L PF11099.8 EMG45432.1 - 4.3 7.6 21.7 0.89 9.8 1.2 5.5 3 3 3 6 6 6 0 Apoptosis regulator M11L like His_Phos_1 PF00300.22 EMG45433.1 - 2.1e-09 37.4 0.4 6.1e-09 35.9 0.4 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 EMG45434.1 - 3.6e-07 30.1 0.8 1.5e-06 28.0 0.8 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Brr6_like_C_C PF10104.9 EMG45435.1 - 3.4e-40 136.9 4.9 4.7e-40 136.4 4.9 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain UL45 PF05473.12 EMG45435.1 - 0.02 14.6 0.0 0.036 13.7 0.0 1.4 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like PKcGMP_CC PF16808.5 EMG45435.1 - 8.3 6.4 11.5 0.36 10.7 2.9 2.7 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ABC_membrane PF00664.23 EMG45436.1 - 5.2e-97 324.8 36.1 3.6e-56 190.8 17.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMG45436.1 - 6.9e-57 191.8 0.1 1.4e-27 96.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMG45436.1 - 9.6e-18 64.4 4.9 1.3e-05 24.8 0.0 4.7 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMG45436.1 - 1.1e-08 35.3 9.3 0.00026 20.9 0.2 3.9 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMG45436.1 - 2.9e-08 33.3 0.1 0.0043 16.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMG45436.1 - 1.2e-06 28.6 0.0 0.03 14.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EMG45436.1 - 4.1e-06 27.5 3.8 0.026 15.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EMG45436.1 - 0.00031 21.3 1.3 0.43 11.1 0.0 4.2 4 1 0 4 4 3 1 AAA domain AAA_22 PF13401.6 EMG45436.1 - 0.00047 20.4 0.2 2.6 8.3 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 EMG45436.1 - 0.00077 19.3 13.9 0.13 12.0 0.7 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EMG45436.1 - 0.0012 18.9 0.2 0.44 10.6 0.0 3.4 4 0 0 4 4 4 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 EMG45436.1 - 0.0022 18.2 0.4 3.5 7.9 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 EMG45436.1 - 0.0042 17.2 0.4 0.32 11.0 0.1 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain Ploopntkinase3 PF18751.1 EMG45436.1 - 0.0067 16.4 0.0 4.6 7.1 0.0 2.4 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 EMG45436.1 - 0.021 14.5 0.0 7.9 6.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.11 EMG45436.1 - 0.023 14.8 0.0 0.73 9.9 0.0 2.8 2 0 0 2 2 2 0 tRNA ligase kinase domain CbiA PF01656.23 EMG45436.1 - 0.026 14.6 0.1 4.3 7.4 0.0 3.0 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 EMG45436.1 - 0.031 14.0 0.1 4.6 6.9 0.0 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EMG45436.1 - 0.041 14.3 0.0 1.5 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 EMG45436.1 - 0.056 13.0 0.3 0.16 11.6 0.1 1.9 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EMG45436.1 - 0.06 12.9 0.1 0.82 9.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EMG45436.1 - 0.065 12.5 0.0 3.8 6.8 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin ABC_ATPase PF09818.9 EMG45436.1 - 0.098 11.4 0.2 0.74 8.5 0.0 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 EMG45436.1 - 0.12 12.1 0.1 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EMG45436.1 - 0.12 12.3 0.6 29 4.5 0.1 3.3 3 0 0 3 3 3 0 NTPase Trp_repressor PF01371.19 EMG45436.1 - 0.15 12.2 0.2 0.68 10.1 0.0 2.2 2 0 0 2 2 1 0 Trp repressor protein Roc PF08477.13 EMG45436.1 - 0.19 12.0 0.5 32 4.8 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Zn_clus PF00172.18 EMG45437.1 - 7.2e-09 35.6 15.2 1.2e-08 34.9 15.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 EMG45438.1 - 1.4e-43 149.2 0.0 6.5e-42 143.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Cullin PF00888.22 EMG45439.1 - 2.9e-20 72.5 2.8 2.9e-20 72.5 2.8 2.4 2 1 0 2 2 2 1 Cullin family ANAPC2 PF08672.11 EMG45439.1 - 9e-16 58.1 3.5 4e-15 56.1 1.3 2.8 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Helicase_C PF00271.31 EMG45440.1 - 8.6e-16 58.3 1.3 2e-15 57.1 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMG45440.1 - 2.2e-14 53.5 0.0 1.1e-13 51.4 0.0 2.3 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EMG45440.1 - 9.5e-14 51.6 1.0 5.6e-13 49.1 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 EMG45440.1 - 3.2e-12 46.6 2.1 4.3e-12 46.2 0.6 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.22 EMG45440.1 - 3.2e-09 37.1 0.2 1.1e-08 35.4 0.2 2.0 1 0 0 1 1 1 1 RWD domain AAA_19 PF13245.6 EMG45440.1 - 0.00094 19.5 0.2 0.0023 18.3 0.2 1.6 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.7 EMG45440.1 - 0.0015 18.7 0.1 0.0036 17.5 0.1 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 PhoH PF02562.16 EMG45440.1 - 0.0016 17.9 0.0 0.005 16.3 0.0 1.8 1 0 0 1 1 1 1 PhoH-like protein AAA_29 PF13555.6 EMG45440.1 - 0.0017 18.1 0.5 0.0066 16.2 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMG45440.1 - 0.0021 18.4 0.3 0.0097 16.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 EMG45440.1 - 0.0031 16.9 1.4 0.0062 15.9 0.1 2.1 2 0 0 2 2 2 1 KaiC AAA_30 PF13604.6 EMG45440.1 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EMG45440.1 - 0.0076 15.3 0.1 0.016 14.3 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ERCC3_RAD25_C PF16203.5 EMG45440.1 - 0.027 13.7 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase AAA_16 PF13191.6 EMG45440.1 - 0.052 13.9 0.1 0.44 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain UBA PF00627.31 EMG45440.1 - 0.063 13.2 0.0 0.73 9.8 0.0 2.5 3 0 0 3 3 3 0 UBA/TS-N domain ABC_tran PF00005.27 EMG45440.1 - 2.8 8.5 5.1 1.9 9.0 0.1 3.4 4 0 0 4 4 3 0 ABC transporter Cullin_binding PF03556.15 EMG45441.1 - 9.2e-23 81.0 2.7 9.2e-23 81.0 2.7 1.9 1 1 1 2 2 2 1 Cullin binding UBA_4 PF14555.6 EMG45441.1 - 2.9e-08 33.4 0.0 6.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EMG45441.1 - 0.0024 17.5 0.0 0.0061 16.2 0.0 1.7 1 0 0 1 1 1 1 TAP C-terminal domain EF-hand_like PF09279.11 EMG45441.1 - 0.11 13.0 1.9 0.66 10.5 0.0 2.9 3 1 1 4 4 4 0 Phosphoinositide-specific phospholipase C, efhand-like Macoilin PF09726.9 EMG45442.1 - 3.2 6.2 14.0 3.5 6.1 14.0 1.0 1 0 0 1 1 1 0 Macoilin family Pneumo_att_G PF05539.11 EMG45442.1 - 8.9 5.8 12.1 8.9 5.8 12.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Slu7 PF11708.8 EMG45443.1 - 7.8e-26 91.4 23.4 2.2e-16 60.4 11.2 3.2 1 1 2 3 3 3 3 Pre-mRNA splicing Prp18-interacting factor AC_N PF16214.5 EMG45443.1 - 0.14 11.3 1.1 1.1 8.3 0.4 2.0 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region ChitinaseA_N PF08329.10 EMG45444.1 - 0.041 13.5 0.3 0.07 12.8 0.3 1.3 1 0 0 1 1 1 0 Chitinase A, N-terminal domain HLH PF00010.26 EMG45445.1 - 8.5e-11 41.7 0.4 8.5e-11 41.7 0.4 2.5 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain DNTTIP1_dimer PF18192.1 EMG45446.1 - 0.0093 16.3 0.1 0.026 14.9 0.1 1.8 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain AA_permease PF00324.21 EMG45447.1 - 1.6e-51 175.4 46.9 2e-51 175.1 46.9 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EMG45447.1 - 5.2e-09 35.6 22.7 6.7e-05 22.1 0.0 4.4 3 1 0 4 4 4 3 Solute carrier family 12 Spt5_N PF11942.8 EMG45447.1 - 1.2 10.2 14.9 3.4 8.7 9.9 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal MULE PF10551.9 EMG45448.1 - 0.03 14.7 0.0 0.08 13.4 0.0 1.7 1 0 0 1 1 1 0 MULE transposase domain DEAD PF00270.29 EMG45449.1 - 1.6e-50 171.3 0.1 3.4e-50 170.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG45449.1 - 1.6e-25 89.6 0.0 3.4e-24 85.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain KIND PF16474.5 EMG45449.1 - 0.99 9.3 8.5 0.67 9.8 5.3 2.2 2 1 0 2 2 2 0 Kinase non-catalytic C-lobe domain ECH_1 PF00378.20 EMG45450.1 - 7.5e-24 84.4 0.0 9.4e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMG45450.1 - 2.7e-18 66.6 0.0 3e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Autophagy_C PF10381.9 EMG45450.1 - 0.032 13.8 0.3 0.072 12.6 0.3 1.5 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal ATP13 PF12921.7 EMG45451.1 - 2.2e-29 101.6 0.2 8.9e-29 99.7 0.1 2.2 2 0 0 2 2 2 1 Mitochondrial ATPase expression DUF4734 PF15881.5 EMG45451.1 - 0.065 13.4 1.2 0.33 11.1 0.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4734) SecE PF00584.20 EMG45452.1 - 1.1e-05 25.2 0.0 1.3e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CofC PF01983.16 EMG45452.1 - 0.09 12.0 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 Guanylyl transferase CofC like Nop52 PF05997.12 EMG45453.1 - 5.3e-72 242.1 2.7 6.7e-72 241.8 2.7 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 SLD3 PF08639.10 EMG45454.1 - 1.1e-39 136.6 42.8 1.5e-37 129.6 42.8 3.7 1 1 0 1 1 1 1 DNA replication regulator SLD3 TAF6_C PF07571.13 EMG45455.1 - 1.3e-27 95.9 0.1 5.1e-27 94.0 0.1 2.0 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EMG45455.1 - 2.5e-24 85.2 0.4 6.5e-24 83.9 0.1 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EMG45455.1 - 8.5e-09 35.9 0.1 8.7e-06 26.1 0.2 2.3 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EMG45455.1 - 0.0023 18.2 0.6 0.0049 17.1 0.3 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EMG45455.1 - 0.027 14.5 0.1 0.075 13.1 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DHHA1 PF02272.19 EMG45455.1 - 0.1 13.0 1.9 0.19 12.2 0.4 2.2 3 0 0 3 3 3 0 DHHA1 domain Bromo_TP PF07524.13 EMG45455.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Bromodomain associated PRKG1_interact PF15898.5 EMG45458.1 - 0.61 11.0 10.5 1.5 9.7 10.5 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CCDC-167 PF15188.6 EMG45458.1 - 2.5 8.5 9.4 11 6.4 9.4 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 SlyX PF04102.12 EMG45458.1 - 6.4 7.5 8.4 5.1 7.8 4.4 2.3 2 0 0 2 2 2 0 SlyX Pkinase PF00069.25 EMG45459.1 - 2.1e-57 194.5 0.0 3.5e-57 193.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45459.1 - 1.3e-19 70.5 0.0 2.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.7 EMG45459.1 - 2.5e-06 27.7 0.0 0.0017 18.6 0.0 3.2 3 0 0 3 3 3 1 PAS domain Kinase-like PF14531.6 EMG45459.1 - 7.7e-06 25.4 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS_8 PF13188.7 EMG45459.1 - 0.0035 17.3 0.0 2.3 8.4 0.0 2.8 2 0 0 2 2 2 1 PAS domain Haspin_kinase PF12330.8 EMG45459.1 - 0.0083 15.1 0.2 0.0083 15.1 0.2 2.6 3 0 0 3 3 3 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EMG45459.1 - 0.01 14.7 0.0 0.01 14.7 0.0 2.2 3 0 0 3 3 3 0 Fungal protein kinase Kdo PF06293.14 EMG45459.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.10 EMG45459.1 - 0.012 15.8 0.0 0.041 14.1 0.0 1.8 2 0 0 2 2 2 0 PAS fold APH PF01636.23 EMG45459.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EMG45459.1 - 0.028 14.1 0.1 0.087 12.4 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Phage_HK97_TLTM PF06120.11 EMG45459.1 - 0.03 13.5 1.4 0.059 12.5 1.4 1.4 1 0 0 1 1 1 0 Tail length tape measure protein PAS PF00989.25 EMG45459.1 - 0.071 13.1 0.0 15 5.6 0.0 2.7 2 0 0 2 2 2 0 PAS fold Seadorna_VP7 PF07387.11 EMG45459.1 - 0.078 12.0 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Macoilin PF09726.9 EMG45460.1 - 0.25 9.9 12.4 0.29 9.6 12.4 1.1 1 0 0 1 1 1 0 Macoilin family HTH_19 PF12844.7 EMG45460.1 - 1.1 9.3 4.5 11 6.1 0.3 3.6 4 0 0 4 4 4 0 Helix-turn-helix domain Suf PF05843.14 EMG45460.1 - 7.8 6.4 13.1 38 4.1 12.8 2.1 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) ABC2_membrane PF01061.24 EMG45461.1 - 3.8e-82 274.8 58.0 1.7e-42 145.2 23.2 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 EMG45461.1 - 3.5e-38 129.4 1.2 9.8e-32 108.7 0.0 3.3 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 EMG45461.1 - 4.3e-24 85.6 0.0 1.2e-18 68.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EMG45461.1 - 2e-05 24.5 0.0 5.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EMG45461.1 - 5.8e-05 22.8 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EMG45461.1 - 0.00016 21.6 0.1 0.18 11.6 0.0 2.8 2 1 1 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMG45461.1 - 0.00044 20.7 0.0 0.00094 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 EMG45461.1 - 0.0022 17.1 16.9 0.0022 17.1 16.9 3.2 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.6 EMG45461.1 - 0.0023 18.5 0.0 0.0056 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EMG45461.1 - 0.0079 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EMG45461.1 - 0.014 15.1 0.1 0.037 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EMG45461.1 - 0.022 13.5 0.0 3.6 6.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EMG45461.1 - 0.03 14.1 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 EMG45461.1 - 0.03 13.7 0.0 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMG45461.1 - 0.037 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMG45461.1 - 0.041 14.4 0.0 0.096 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EMG45461.1 - 0.046 12.5 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class NACHT PF05729.12 EMG45461.1 - 0.2 11.5 0.3 3.4 7.5 0.1 2.5 2 0 0 2 2 2 0 NACHT domain PEMT PF04191.13 EMG45462.1 - 1.2e-34 118.9 3.7 2.6e-34 117.8 3.7 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Vps55 PF04133.14 EMG45462.1 - 0.84 9.6 7.5 6.5 6.7 0.3 3.0 3 0 0 3 3 3 0 Vacuolar protein sorting 55 Sugar_tr PF00083.24 EMG45463.1 - 2.1e-38 132.4 28.6 2.9e-38 131.9 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG45463.1 - 9.6e-33 113.6 49.4 4.1e-30 104.9 30.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2219 PF09982.9 EMG45463.1 - 0.14 11.4 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2219) LapA_dom PF06305.11 EMG45463.1 - 0.3 10.9 1.9 39 4.1 0.8 3.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain UCR_UQCRX_QCR9 PF05365.12 EMG45463.1 - 0.4 10.7 0.1 0.4 10.7 0.1 3.4 4 0 0 4 4 4 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Sacchrp_dh_C PF16653.5 EMG45464.1 - 5.1e-94 315.3 0.0 1.1e-93 314.2 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EMG45464.1 - 1.2e-24 87.1 0.5 1.8e-24 86.5 0.5 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMG45464.1 - 1.5e-07 31.6 0.2 2.9e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EMG45464.1 - 2.5e-07 30.7 0.6 4.6e-07 29.9 0.6 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EMG45464.1 - 0.0035 17.8 0.2 0.007 16.8 0.2 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 EMG45464.1 - 0.0075 16.9 0.5 0.018 15.7 0.5 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EMG45464.1 - 0.017 15.3 0.7 0.034 14.3 0.7 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 EMG45464.1 - 0.031 15.1 0.1 0.087 13.7 0.1 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 EMG45464.1 - 0.19 12.0 1.8 0.23 11.7 0.7 1.7 2 0 0 2 2 2 0 TrkA-N domain Tubulin_3 PF14881.6 EMG45465.1 - 7.2e-29 100.8 0.2 1.4e-28 99.8 0.2 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EMG45465.1 - 6e-20 71.7 0.4 4.7e-19 68.8 0.4 2.3 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EMG45465.1 - 1.8e-05 25.1 0.0 0.00032 21.0 0.0 2.4 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tup_N PF08581.10 EMG45466.1 - 0.017 15.4 0.2 3.3 8.1 0.0 2.9 2 0 0 2 2 2 0 Tup N-terminal Trypan_PARP PF05887.11 EMG45466.1 - 7.2 6.6 21.8 0.25 11.3 5.8 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L7Ae PF01248.26 EMG45467.1 - 3.3e-23 81.2 0.7 5.6e-23 80.5 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EMG45467.1 - 0.0033 17.5 0.1 0.0051 16.9 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 EF-hand_like PF09279.11 EMG45467.1 - 0.11 13.0 0.2 0.68 10.5 0.1 2.1 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF2145 PF09916.9 EMG45468.1 - 0.052 13.2 0.2 0.092 12.4 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) Sugar_tr PF00083.24 EMG45469.1 - 3.7e-100 335.9 11.8 4.5e-100 335.7 11.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG45469.1 - 2e-35 122.4 43.7 9.8e-32 110.2 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMG45469.1 - 0.007 15.3 10.2 0.057 12.3 0.1 2.6 3 0 0 3 3 3 2 MFS_1 like family OATP PF03137.20 EMG45469.1 - 0.6 8.3 11.7 0.11 10.7 2.5 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ELO PF01151.18 EMG45470.1 - 1e-64 218.5 12.9 1.3e-64 218.1 12.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Colicin_K PF17500.2 EMG45470.1 - 0.031 14.8 0.7 0.031 14.8 0.7 3.2 3 1 0 3 3 3 0 Colicin-K KH_1 PF00013.29 EMG45471.1 - 2.8e-15 55.9 3.6 5.4e-07 29.3 0.1 4.8 5 0 0 5 5 5 3 KH domain DUF4296 PF14129.6 EMG45471.1 - 0.033 14.8 1.0 0.24 12.0 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4296) DUF4974 PF16344.5 EMG45471.1 - 0.86 9.7 8.9 1.2 9.1 0.4 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4974) UDG PF03167.19 EMG45472.1 - 8.1e-10 38.9 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily TFB6 PF17110.5 EMG45473.1 - 1.9e-12 47.3 0.4 8.9e-12 45.1 0.0 2.2 2 1 1 3 3 3 1 Subunit 11 of the general transcription factor TFIIH Vac_ImportDeg PF09783.9 EMG45474.1 - 2.5e-57 193.2 2.4 2.5e-57 193.2 2.4 1.7 2 0 0 2 2 2 1 Vacuolar import and degradation protein AAA_6 PF12774.7 EMG45477.1 - 2e-113 378.7 0.1 5.1e-112 374.1 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EMG45477.1 - 1.7e-100 337.0 15.8 1.7e-100 337.0 15.8 5.9 6 1 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EMG45477.1 - 1.4e-58 197.7 0.5 1.4e-58 197.7 0.5 5.0 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EMG45477.1 - 1.5e-46 158.2 0.0 4.8e-38 130.5 0.0 4.9 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_8 PF12780.7 EMG45477.1 - 1.7e-46 158.7 4.6 1.7e-46 158.6 0.0 3.5 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 EMG45477.1 - 2.5e-42 145.3 22.2 2.5e-42 145.3 22.2 4.8 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 MT PF12777.7 EMG45477.1 - 6.5e-32 110.9 3.2 6.5e-32 110.9 3.2 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EMG45477.1 - 8.5e-30 103.7 0.0 3e-29 101.9 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EMG45477.1 - 4.5e-25 88.3 0.2 1.1e-09 38.4 0.0 6.1 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EMG45477.1 - 3.3e-19 69.1 0.0 4.1e-16 59.1 0.1 3.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 EMG45477.1 - 5e-15 56.1 2.8 0.001 19.5 0.0 5.8 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMG45477.1 - 1.2e-14 54.7 14.4 0.0069 16.7 0.0 8.9 10 0 0 10 10 8 3 AAA domain Dynein_AAA_lid PF17852.1 EMG45477.1 - 1.2e-11 44.8 0.2 7.5e-11 42.2 0.2 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EMG45477.1 - 1.6e-11 44.8 0.0 0.017 15.5 0.0 5.8 5 0 0 5 5 4 2 AAA ATPase domain AAA_33 PF13671.6 EMG45477.1 - 1.2e-10 41.7 0.3 0.041 14.0 0.0 4.9 5 0 0 5 5 4 3 AAA domain AAA_29 PF13555.6 EMG45477.1 - 3.2e-08 33.2 0.2 0.012 15.3 0.1 4.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_18 PF13238.6 EMG45477.1 - 1.5e-07 32.0 0.1 10 6.7 0.0 6.0 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.6 EMG45477.1 - 2e-07 31.1 5.1 0.049 13.7 0.0 7.2 7 1 1 8 8 6 1 AAA domain T2SSE PF00437.20 EMG45477.1 - 4.9e-07 29.1 0.6 0.2 10.7 0.0 3.7 4 0 0 4 4 3 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EMG45477.1 - 1.7e-06 27.6 0.0 0.44 9.9 0.0 5.0 4 0 0 4 4 4 1 FtsK/SpoIIIE family Mg_chelatase PF01078.21 EMG45477.1 - 9.4e-06 25.2 2.0 0.44 9.9 0.0 4.0 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 EMG45477.1 - 1.5e-05 25.1 4.8 1.5e-05 25.1 0.1 3.8 3 0 0 3 3 1 1 AAA+ lid domain AAA_19 PF13245.6 EMG45477.1 - 1.9e-05 25.0 1.2 1.7 8.9 0.0 5.4 5 0 0 5 5 4 1 AAA domain ABC_tran PF00005.27 EMG45477.1 - 2.5e-05 24.8 10.2 0.023 15.2 0.0 6.2 6 0 0 6 6 4 1 ABC transporter RNA_helicase PF00910.22 EMG45477.1 - 3.9e-05 24.0 0.9 3.7 8.0 0.0 6.1 6 0 0 6 6 5 1 RNA helicase AAA_30 PF13604.6 EMG45477.1 - 6.7e-05 22.7 0.4 1.9 8.1 0.0 4.6 4 1 0 4 4 4 1 AAA domain IstB_IS21 PF01695.17 EMG45477.1 - 7.6e-05 22.5 0.0 1.6 8.4 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 EMG45477.1 - 0.00016 21.5 0.1 16 5.1 0.0 5.0 4 0 0 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 EMG45477.1 - 0.00021 21.2 0.1 0.22 11.4 0.1 4.3 4 0 0 4 4 3 1 RsgA GTPase MMR_HSR1 PF01926.23 EMG45477.1 - 0.0038 17.3 0.3 0.57 10.3 0.0 4.0 4 0 0 4 4 2 1 50S ribosome-binding GTPase TsaE PF02367.17 EMG45477.1 - 0.0051 16.8 0.3 1.5 8.8 0.0 4.4 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EMG45477.1 - 0.0053 16.3 0.0 4.2 6.9 0.0 3.8 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 EMG45477.1 - 0.0065 16.4 2.5 0.35 10.8 0.0 4.0 4 0 0 4 4 3 1 NACHT domain Roc PF08477.13 EMG45477.1 - 0.007 16.6 1.3 0.95 9.7 0.1 4.1 4 0 0 4 4 3 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EMG45477.1 - 0.017 14.4 0.1 4.4 6.5 0.0 3.8 4 0 0 4 4 3 0 Zeta toxin Rad17 PF03215.15 EMG45477.1 - 0.024 14.6 22.5 6.5 6.6 0.0 8.2 9 0 0 9 9 7 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 EMG45477.1 - 0.037 13.7 0.1 2.4 7.8 0.0 3.5 3 0 0 3 3 3 0 Cytidylate kinase Sigma54_activat PF00158.26 EMG45477.1 - 0.048 13.4 0.0 7.1 6.3 0.0 3.7 3 0 0 3 3 3 0 Sigma-54 interaction domain cobW PF02492.19 EMG45477.1 - 0.074 12.6 0.2 23 4.5 0.1 3.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 EMG45477.1 - 0.43 10.3 0.0 0.43 10.3 0.0 4.7 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 EMG45477.1 - 0.55 10.1 6.4 12 5.8 0.0 5.1 5 0 0 5 5 4 0 NTPase BRE1 PF08647.11 EMG45477.1 - 1.1 9.4 34.8 0.0058 16.7 5.0 5.4 4 0 0 4 4 3 0 BRE1 E3 ubiquitin ligase Flo11 PF10182.9 EMG45477.1 - 7.1 6.8 9.6 0.6 10.2 0.6 3.3 3 0 0 3 3 3 0 Flo11 domain EZH2_WD-Binding PF11616.8 EMG45477.1 - 8.8 6.5 9.7 16 5.7 1.6 3.7 3 0 0 3 3 3 0 WD repeat binding protein EZH2 ABC_trans_N PF14510.6 EMG45478.1 - 3.1e-22 79.0 2.3 4.4e-22 78.5 0.0 2.1 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC_tran PF00005.27 EMG45478.1 - 5.2e-08 33.5 0.0 1.2e-07 32.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 EMG45478.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EMG45478.1 - 0.17 12.3 0.2 3.9 7.9 0.2 2.4 1 1 0 1 1 1 0 AAA domain SH3_1 PF00018.28 EMG45479.1 - 3.2e-10 39.4 0.1 9.7e-10 37.9 0.0 1.9 2 0 0 2 2 2 1 SH3 domain PX PF00787.24 EMG45479.1 - 1.1e-08 35.0 0.6 1.1e-08 35.0 0.6 3.0 3 0 0 3 3 3 1 PX domain SH3_9 PF14604.6 EMG45479.1 - 1.5e-05 24.7 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMG45479.1 - 5.9e-05 22.7 0.0 0.00015 21.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain RSN1_7TM PF02714.15 EMG45480.1 - 8.1e-82 274.6 35.1 8.1e-82 274.6 35.1 2.3 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EMG45480.1 - 3.7e-33 114.5 10.2 3.7e-33 114.5 10.2 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EMG45480.1 - 9.3e-24 84.6 3.4 4.1e-23 82.5 3.4 1.9 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Zn_clus PF00172.18 EMG45481.1 - 1.1e-06 28.6 5.9 1.9e-06 27.9 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AcetDehyd-dimer PF09290.11 EMG45484.1 - 0.2 11.9 0.1 0.26 11.5 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Pkinase PF00069.25 EMG45485.1 - 1.9e-69 234.0 0.6 2.4e-69 233.6 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45485.1 - 2.9e-37 128.4 0.0 3.9e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG45485.1 - 7.5e-07 28.3 0.1 1.5e-06 27.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EMG45485.1 - 0.00022 20.3 0.3 0.0003 19.8 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 EMG45485.1 - 0.015 15.9 0.6 0.036 14.8 0.6 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain RhoGAP PF00620.27 EMG45486.1 - 6.4e-43 146.2 0.5 3.8e-42 143.7 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EMG45486.1 - 3.3e-09 36.9 0.1 1e-08 35.4 0.1 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain ZnuA PF01297.17 EMG45486.1 - 0.0083 15.6 2.3 0.98 8.8 0.0 2.6 2 0 0 2 2 2 2 Zinc-uptake complex component A periplasmic CAP_N PF01213.19 EMG45486.1 - 0.039 13.4 4.0 0.034 13.6 0.7 2.5 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Sec20 PF03908.13 EMG45486.1 - 2.8 7.9 11.0 0.71 9.8 0.2 4.2 3 1 0 4 4 4 0 Sec20 Chs7 PF12271.8 EMG45487.1 - 2.4e-119 398.0 25.3 2.7e-119 397.8 25.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone NPCC PF08058.11 EMG45487.1 - 2.4 8.2 7.2 4.3 7.4 2.6 2.3 2 0 0 2 2 2 0 Nuclear pore complex component DUF4149 PF13664.6 EMG45487.1 - 5.8 7.3 21.1 0.16 12.3 1.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) Ndr PF03096.14 EMG45488.1 - 0.0083 14.9 0.5 0.018 13.8 0.5 1.5 1 0 0 1 1 1 1 Ndr family Peptidase_C12 PF01088.21 EMG45489.1 - 4.9e-51 173.5 0.0 5.4e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Peptidase_C39 PF03412.15 EMG45489.1 - 0.026 14.3 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family MMS19_C PF12460.8 EMG45489.1 - 0.036 13.2 1.0 0.055 12.6 1.0 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal HCMV_UL124 PF17609.2 EMG45490.1 - 0.1 12.8 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function PRA1 PF03208.19 EMG45492.1 - 4.8e-38 130.0 0.5 5.8e-38 129.7 0.5 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 EMG45492.1 - 0.15 10.8 0.5 0.17 10.6 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_S8 PF00410.19 EMG45493.1 - 6.7e-24 84.3 0.1 1e-23 83.7 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.19 EMG45494.1 - 4.5e-46 155.8 1.6 5.4e-46 155.5 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EMG45494.1 - 0.11 12.7 0.1 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) BET PF17035.5 EMG45495.1 - 0.047 13.9 0.1 0.16 12.2 0.1 1.9 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation DUF3445 PF11927.8 EMG45496.1 - 3.5e-66 223.1 0.1 4.3e-66 222.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Sel1 PF08238.12 EMG45497.1 - 1.1e-06 29.0 0.5 0.0047 17.6 0.1 3.1 3 0 0 3 3 3 2 Sel1 repeat DRMBL PF07522.14 EMG45498.1 - 0.035 14.3 1.9 0.047 13.9 0.1 2.2 3 0 0 3 3 3 0 DNA repair metallo-beta-lactamase CtsR PF05848.11 EMG45498.1 - 0.081 12.9 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 CtsR N-terminal HTH domain UCH PF00443.29 EMG45499.1 - 4.3e-71 239.4 1.5 4.3e-71 239.4 1.5 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMG45499.1 - 6.9e-10 39.0 4.0 0.001 18.7 0.1 3.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EMG45499.1 - 7.8e-07 29.6 0.5 1.1e-05 26.0 0.1 3.1 2 0 0 2 2 2 1 DUSP domain CobT PF06213.12 EMG45499.1 - 0.32 10.3 14.0 0.029 13.8 7.7 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Prothymosin PF03247.14 EMG45499.1 - 7.8 7.0 30.9 0.25 11.8 19.7 3.3 3 0 0 3 3 3 0 Prothymosin/parathymosin family Beach PF02138.18 EMG45500.1 - 3.2e-118 394.1 0.7 3.2e-118 394.1 0.7 2.0 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 EMG45500.1 - 1.2e-09 38.2 0.0 4.1e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH MFS_1 PF07690.16 EMG45501.1 - 4.9e-29 101.4 41.7 1.2e-17 63.9 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG45501.1 - 0.00019 20.4 16.3 0.00019 20.4 16.3 3.0 1 1 1 3 3 3 2 Sugar (and other) transporter DUF2012 PF09430.10 EMG45502.1 - 3.4e-05 23.9 0.4 6.4e-05 23.1 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 EMG45502.1 - 0.0043 16.6 4.3 0.01 15.4 4.3 1.7 1 1 0 1 1 1 1 Suppressor of PMA 1-7 protein Med26 PF08711.11 EMG45503.1 - 1.8e-09 37.5 0.1 4e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain T2SSM PF04612.12 EMG45503.1 - 0.14 12.2 0.2 0.14 12.2 0.2 2.8 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M Ribosom_S12_S23 PF00164.25 EMG45504.1 - 3.2e-51 171.7 0.2 4.2e-51 171.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mito_carr PF00153.27 EMG45505.1 - 3.6e-52 174.3 0.9 5.9e-19 67.8 0.2 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein LisH PF08513.11 EMG45506.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 LisH DUF4817 PF16087.5 EMG45506.1 - 0.05 13.4 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) LisH_2 PF16045.5 EMG45506.1 - 0.063 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 LisH GATase_2 PF00310.21 EMG45507.1 - 1.8e-180 600.2 0.0 2.7e-180 599.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EMG45507.1 - 7.4e-153 509.0 0.1 4.8e-152 506.4 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EMG45507.1 - 4.8e-111 370.7 0.1 2.7e-108 361.7 0.2 2.3 2 0 0 2 2 2 2 Glutamate synthase central domain GXGXG PF01493.19 EMG45507.1 - 3.5e-82 274.6 4.6 5.7e-82 273.9 4.6 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EMG45507.1 - 5.6e-23 81.6 0.3 8.5e-22 77.7 0.3 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EMG45507.1 - 3.5e-21 75.1 0.1 7.3e-21 74.0 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 EMG45507.1 - 3.6e-10 40.3 0.0 1.7e-06 28.5 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMG45507.1 - 1.1e-08 35.2 0.0 4.4e-08 33.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EMG45507.1 - 7.9e-07 28.7 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EMG45507.1 - 4.6e-05 22.3 2.3 4.7e-05 22.3 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 EMG45507.1 - 8.5e-05 22.1 0.1 0.00017 21.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EMG45507.1 - 0.00013 21.7 0.6 0.0016 18.1 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMG45507.1 - 0.00014 21.3 0.1 0.09 12.0 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMG45507.1 - 0.00015 21.0 0.1 0.00031 19.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EMG45507.1 - 0.00049 19.4 0.4 0.0062 15.8 0.1 2.6 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 EMG45507.1 - 0.00066 19.0 0.0 0.0017 17.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EMG45507.1 - 0.0036 16.4 0.7 0.012 14.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 EMG45507.1 - 0.0043 16.4 0.0 0.078 12.3 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EMG45507.1 - 0.0065 16.9 1.0 0.96 9.9 0.0 2.8 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 EMG45507.1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 EMG45507.1 - 0.028 13.7 0.1 0.85 8.9 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EMG45507.1 - 0.064 12.3 0.3 0.14 11.2 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein AdoHcyase_NAD PF00670.21 EMG45507.1 - 0.084 12.9 0.6 12 6.0 0.0 3.1 3 0 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMN_dh PF01070.18 EMG45507.1 - 0.12 11.4 0.2 0.4 9.6 0.2 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase IlvN PF07991.12 EMG45507.1 - 0.14 11.7 1.0 0.58 9.7 0.0 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain RNase_PH PF01138.21 EMG45508.1 - 1.4e-09 38.5 0.0 4.4e-09 36.9 0.0 1.8 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 CAP PF00188.26 EMG45509.1 - 1e-18 68.4 1.1 2.6e-18 67.0 1.1 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SOG2 PF10428.9 EMG45509.1 - 4.5 6.4 16.1 6.1 5.9 16.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein K_trans PF02705.16 EMG45511.1 - 3.4e-156 520.9 19.5 4.3e-156 520.5 19.5 1.1 1 0 0 1 1 1 1 K+ potassium transporter LSM14 PF12701.7 EMG45512.1 - 1.4e-26 92.4 0.0 2.4e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 EMG45512.1 - 1.4e-05 25.1 0.0 3.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 EMG45512.1 - 5.7e-05 23.9 12.3 0.00068 20.5 1.2 3.8 2 2 2 4 4 4 2 FDF domain GRP PF07172.11 EMG45512.1 - 0.68 10.7 10.3 2 9.2 10.3 1.7 1 0 0 1 1 1 0 Glycine rich protein family LRR_8 PF13855.6 EMG45513.1 - 1.5e-28 98.4 35.9 6.8e-07 29.0 2.6 7.9 3 2 4 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EMG45513.1 - 9.3e-22 76.8 53.2 0.0012 19.1 0.2 11.3 6 2 4 12 12 12 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMG45513.1 - 1.5e-10 40.2 28.6 1.7 8.9 0.0 12.2 13 0 0 13 13 13 4 Leucine Rich repeat LRR_9 PF14580.6 EMG45513.1 - 1.1e-07 31.5 21.0 0.0013 18.3 2.8 5.1 1 1 4 5 5 5 4 Leucine-rich repeat FNIP PF05725.12 EMG45513.1 - 0.24 11.6 30.1 1.2 9.4 0.5 8.3 6 4 3 9 9 9 0 FNIP Repeat Pept_S41_N PF18294.1 EMG45513.1 - 0.3 11.1 5.7 0.061 13.3 1.0 2.3 3 0 0 3 3 3 0 Peptidase S41 N-terminal domain LRR_1 PF00560.33 EMG45513.1 - 0.75 10.6 47.3 14 6.7 0.0 12.7 12 4 1 13 13 13 0 Leucine Rich Repeat GTP_EFTU PF00009.27 EMG45514.1 - 2.4e-64 216.5 0.6 4.5e-64 215.6 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EMG45514.1 - 2e-25 88.6 0.1 4.4e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EMG45514.1 - 5.8e-15 55.1 0.2 8.9e-10 38.5 0.0 2.9 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMG45514.1 - 2.9e-10 40.4 0.0 1e-09 38.7 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EMG45514.1 - 0.00025 20.9 0.0 0.00063 19.6 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EMG45514.1 - 0.00046 20.3 0.2 0.0021 18.1 0.2 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EMG45514.1 - 0.064 12.6 0.4 0.65 9.3 0.0 2.6 2 1 1 3 3 3 0 AIG1 family SH3_1 PF00018.28 EMG45515.1 - 5e-08 32.4 0.6 1.2e-07 31.2 0.6 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMG45515.1 - 0.0029 17.2 0.1 0.0059 16.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EMG45515.1 - 0.033 14.0 0.2 0.079 12.8 0.2 1.6 1 0 0 1 1 1 0 Variant SH3 domain Transglut_core PF01841.19 EMG45515.1 - 0.037 14.5 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily PI3_PI4_kinase PF00454.27 EMG45516.1 - 3.7e-48 164.5 0.1 1.5e-47 162.5 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EMG45516.1 - 3.5e-33 114.6 5.4 1.7e-20 73.2 0.6 2.8 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 EMG45516.1 - 2.4e-20 72.9 1.8 3.2e-20 72.5 0.1 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 His_Phos_1 PF00300.22 EMG45517.1 - 0.00091 19.0 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF916 PF06030.12 EMG45517.1 - 0.047 13.8 0.9 0.11 12.5 0.9 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) IFRD PF05004.13 EMG45518.1 - 1.6e-20 73.4 6.6 1.6e-20 73.4 6.6 3.4 2 1 1 3 3 3 1 Interferon-related developmental regulator (IFRD) DRIM PF07539.12 EMG45518.1 - 0.0032 15.9 1.5 0.0034 15.8 0.1 1.6 2 0 0 2 2 2 1 Down-regulated in metastasis MRP-S26 PF14943.6 EMG45518.1 - 0.059 13.3 0.1 0.059 13.3 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial ribosome subunit S26 HEAT_EZ PF13513.6 EMG45518.1 - 0.081 13.5 0.5 0.18 12.4 0.1 1.9 2 0 0 2 2 2 0 HEAT-like repeat Acetyltransf_1 PF00583.25 EMG45519.1 - 1.8e-06 28.2 0.0 2.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EMG45519.1 - 2e-06 27.7 0.0 3.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EMG45519.1 - 9.3e-06 25.6 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMG45519.1 - 5.8e-05 23.4 0.0 0.00014 22.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Mcl1_mid PF12341.8 EMG45520.1 - 2.4e-84 283.2 0.1 1.9e-83 280.2 0.0 2.1 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 EMG45520.1 - 1.7e-06 28.2 0.3 0.73 10.2 0.0 5.1 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EMG45520.1 - 0.0026 17.1 0.1 0.0043 16.4 0.1 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus HPS3_N PF14761.6 EMG45520.1 - 0.0083 15.7 0.2 5.8 6.4 0.0 4.0 4 1 0 4 4 4 1 Hermansky-Pudlak syndrome 3 CNH PF00780.22 EMG45520.1 - 0.011 15.3 0.0 0.13 11.8 0.1 2.4 1 1 0 2 2 2 0 CNH domain Beta_helix_2 PF18835.1 EMG45520.1 - 0.062 13.1 0.3 0.17 11.7 0.3 1.7 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase YL1 PF05764.13 EMG45520.1 - 0.45 10.6 8.9 0.83 9.7 8.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein DUF2457 PF10446.9 EMG45520.1 - 0.53 9.4 12.7 1 8.4 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AAA_12 PF13087.6 EMG45521.1 - 9.2e-58 195.2 1.7 3.7e-57 193.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EMG45521.1 - 3.5e-56 190.9 0.4 3.5e-56 190.9 0.4 2.2 2 1 0 2 2 2 1 AAA domain DUF1748 PF08520.10 EMG45521.1 - 5.3e-24 83.9 0.6 1.8e-23 82.2 0.1 2.3 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1748) AAA_19 PF13245.6 EMG45521.1 - 9.6e-12 45.5 0.1 3.1e-10 40.6 0.0 3.3 3 2 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EMG45521.1 - 2.6e-11 43.6 0.0 3.4e-09 36.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 EMG45521.1 - 2.4e-09 37.3 0.1 0.0016 18.2 0.0 4.0 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EMG45521.1 - 6.5e-09 36.0 0.0 9.6e-08 32.2 0.0 2.7 1 1 2 3 3 3 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 EMG45521.1 - 0.00017 20.9 1.0 0.013 14.7 0.0 3.0 3 0 0 3 3 3 1 PIF1-like helicase PhoH PF02562.16 EMG45521.1 - 0.00028 20.4 0.2 0.0026 17.2 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 EMG45521.1 - 0.00034 20.9 0.3 0.0017 18.6 0.3 2.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EMG45521.1 - 0.00054 19.3 0.4 0.026 13.8 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 EMG45521.1 - 0.002 18.0 0.0 0.01 15.7 0.0 2.3 2 1 0 2 2 2 1 Helicase AAA PF00004.29 EMG45521.1 - 0.0025 18.2 0.2 0.0088 16.5 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMG45521.1 - 0.0028 18.0 0.1 0.016 15.6 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EMG45521.1 - 0.0037 16.4 0.1 0.0068 15.5 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 EMG45521.1 - 0.0045 16.7 0.0 0.035 13.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 EMG45521.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EMG45521.1 - 0.02 15.4 1.7 0.084 13.4 1.7 2.2 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 EMG45521.1 - 0.027 14.4 4.9 0.035 14.0 0.9 3.1 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EMG45521.1 - 0.031 14.4 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EMG45521.1 - 0.05 13.2 0.0 0.18 11.4 0.0 2.0 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_14 PF13173.6 EMG45521.1 - 0.1 12.7 3.2 1.1 9.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EMG45521.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EMG45521.1 - 0.13 12.4 0.6 0.58 10.2 0.1 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Dynamin_N PF00350.23 EMG45521.1 - 1 9.4 8.2 0.42 10.7 0.3 3.3 2 2 1 3 3 3 0 Dynamin family CAP PF00188.26 EMG45522.1 - 2.9e-18 66.9 1.3 4.5e-18 66.3 1.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Trypan_PARP PF05887.11 EMG45522.1 - 7.7e-09 35.6 117.4 0.046 13.7 38.0 3.2 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) PseudoU_synth_2 PF00849.22 EMG45523.1 - 1.1e-23 84.1 0.0 1.7e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase EIF_2_alpha PF07541.12 EMG45524.1 - 1.5e-37 128.2 0.0 3.4e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EMG45524.1 - 3e-15 56.3 1.4 5.3e-15 55.5 1.4 1.4 1 0 0 1 1 1 1 S1 RNA binding domain LZ3wCH PF18517.1 EMG45524.1 - 0.042 14.0 0.1 0.21 11.7 0.0 2.3 2 0 0 2 2 2 0 Leucine zipper with capping helix domain LRR_4 PF12799.7 EMG45525.1 - 4.1e-18 65.2 36.2 0.00023 21.5 3.2 9.4 6 2 3 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG45525.1 - 2.3e-16 59.3 26.0 9.2e-05 22.1 3.3 8.4 5 4 4 9 9 9 6 Leucine rich repeat LRR_6 PF13516.6 EMG45525.1 - 1.8e-11 43.1 1.6 1.1 9.5 0.1 9.8 10 0 0 10 10 10 1 Leucine Rich repeat FNIP PF05725.12 EMG45525.1 - 2.7e-11 43.5 21.4 0.00084 19.5 1.6 7.8 5 3 4 9 9 9 5 FNIP Repeat LRR_1 PF00560.33 EMG45525.1 - 0.027 15.0 32.7 2.6 8.9 0.2 11.6 9 4 2 11 11 11 0 Leucine Rich Repeat LRR_9 PF14580.6 EMG45525.1 - 0.11 12.0 8.1 0.13 11.7 1.3 3.2 3 0 0 3 3 3 0 Leucine-rich repeat DUF2420 PF10336.9 EMG45525.1 - 0.12 12.4 1.0 0.26 11.3 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) Y1_Tnp PF01797.16 EMG45525.1 - 0.15 12.2 0.3 0.31 11.2 0.3 1.5 1 0 0 1 1 1 0 Transposase IS200 like MFS_1 PF07690.16 EMG45526.1 - 7.3e-27 94.2 79.7 3.7e-19 68.9 49.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMG45526.1 - 7.3e-09 34.7 39.2 1.2e-05 24.0 16.8 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein DPM3 PF08285.11 EMG45526.1 - 0.051 13.8 2.3 0.3 11.3 2.3 2.3 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) WD40 PF00400.32 EMG45527.1 - 7.4e-07 29.8 8.4 0.13 13.2 0.1 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat SRA1 PF07304.11 EMG45527.1 - 5.2e-05 23.1 0.0 5.2e-05 23.1 0.0 3.2 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) SUIM_assoc PF16619.5 EMG45527.1 - 0.0068 16.5 4.4 0.37 10.9 4.5 2.6 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Sec16_C PF12931.7 EMG45527.1 - 0.0069 16.1 0.6 0.018 14.7 0.6 1.7 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Toprim_3 PF13362.6 EMG45527.1 - 0.016 15.5 0.1 3.6 8.0 0.0 3.4 3 0 0 3 3 3 0 Toprim domain Prp18 PF02840.15 EMG45527.1 - 0.017 15.2 0.3 0.18 11.9 0.0 2.7 2 1 1 3 3 3 0 Prp18 domain Glyco_hydro_65m PF03632.15 EMG45528.1 - 1.9e-38 132.4 0.9 2.9e-30 105.4 0.9 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 EMG45528.1 - 5.9e-25 88.2 0.0 1e-24 87.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.25 EMG45528.1 - 0.00024 21.2 3.3 0.00032 20.8 1.1 2.2 2 0 0 2 2 2 1 F5/8 type C domain Glyco_hyd_65N_2 PF14498.6 EMG45528.1 - 0.056 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain SPO22 PF08631.10 EMG45529.1 - 3.4e-48 164.5 17.3 7.2e-45 153.6 4.0 3.8 4 0 0 4 4 4 3 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 EMG45529.1 - 8.9e-05 22.9 0.1 0.0054 17.2 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Tom37_C PF11801.8 EMG45529.1 - 0.0012 18.8 0.6 0.0049 16.8 0.6 2.1 1 0 0 1 1 1 1 Tom37 C-terminal domain Coatomer_E PF04733.14 EMG45529.1 - 0.0016 17.9 0.2 0.004 16.6 0.2 1.6 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 EMG45529.1 - 0.015 15.4 3.5 0.3 11.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L34e PF01199.18 EMG45530.1 - 1e-39 134.7 7.1 1e-39 134.7 7.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e zinc_ribbon_12 PF11331.8 EMG45530.1 - 0.062 13.1 1.2 0.29 11.0 0.1 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain zinc_ribbon_5 PF13719.6 EMG45530.1 - 0.064 13.0 1.6 0.064 13.0 1.6 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Cytochrome_C7 PF14522.6 EMG45530.1 - 0.16 12.0 2.2 0.34 10.9 2.2 1.7 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Zn_ribbon_recom PF13408.6 EMG45530.1 - 1.4 9.5 7.9 0.19 12.3 3.7 1.8 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Ribonuc_L-PSP PF01042.21 EMG45531.1 - 9.4e-40 135.4 0.2 1.2e-39 135.1 0.2 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1655 PF07868.11 EMG45532.1 - 0.21 11.7 1.0 0.79 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1655) TMEM135_C_rich PF15982.5 EMG45533.1 - 0.00027 21.6 2.7 0.001 19.7 0.2 2.4 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 GP52 PF17468.2 EMG45533.1 - 0.13 12.5 0.0 0.45 10.7 0.0 1.9 2 0 0 2 2 2 0 Phage gene product 52 DUF5549 PF17703.1 EMG45534.1 - 0.076 12.7 0.6 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5549) Cytomega_TRL10 PF06084.11 EMG45534.1 - 0.7 9.9 5.4 3.8 7.5 1.5 2.2 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein CDC45 PF02724.14 EMG45534.1 - 7.8 4.7 8.1 10 4.3 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PET117 PF15786.5 EMG45535.1 - 1e-26 93.0 1.6 1.2e-26 92.7 1.6 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Cyclin PF08613.11 EMG45536.1 - 9.9e-40 136.5 0.0 9.9e-40 136.5 0.0 4.6 4 2 0 4 4 2 1 Cyclin SDA1 PF05285.12 EMG45536.1 - 0.00028 20.4 13.8 0.00052 19.5 13.8 1.5 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 EMG45536.1 - 0.0017 16.7 15.2 0.003 15.9 15.2 1.4 1 0 0 1 1 1 1 Nop14-like family NOA36 PF06524.12 EMG45536.1 - 0.002 17.5 19.7 0.0035 16.7 19.7 1.4 1 0 0 1 1 1 1 NOA36 protein BUD22 PF09073.10 EMG45536.1 - 0.0031 16.9 12.4 0.01 15.2 12.4 1.9 1 0 0 1 1 1 1 BUD22 CNDH2_C PF16858.5 EMG45536.1 - 0.035 14.0 12.8 0.092 12.6 12.8 1.7 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop25 PF09805.9 EMG45536.1 - 0.34 11.4 20.2 0.025 15.1 14.4 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DNA_pol_phi PF04931.13 EMG45536.1 - 0.39 8.7 24.1 0.75 7.8 24.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EMG45536.1 - 0.53 8.5 13.6 0.84 7.9 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 EMG45536.1 - 1.4 8.6 27.3 0.056 13.2 20.8 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MAS20 PF02064.15 EMG45536.1 - 2.3 8.3 8.0 61 3.7 6.1 2.8 2 0 0 2 2 2 0 MAS20 protein import receptor RTA1 PF04479.13 EMG45537.1 - 8.8e-70 234.5 14.6 8.8e-70 234.5 14.6 1.5 2 0 0 2 2 2 1 RTA1 like protein Pkinase PF00069.25 EMG45540.1 - 1.2e-50 172.4 0.0 1.8e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45540.1 - 9e-25 87.4 0.0 1.4e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMG45540.1 - 0.0097 15.9 0.0 0.023 14.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family ER-remodelling PF14755.6 EMG45540.1 - 0.01 16.2 0.8 0.046 14.0 0.8 2.1 1 0 0 1 1 1 0 Intracellular membrane remodeller Haspin_kinase PF12330.8 EMG45540.1 - 0.017 14.0 0.1 0.017 14.0 0.1 2.9 2 1 1 3 3 3 0 Haspin like kinase domain Ribosomal_L11_N PF03946.14 EMG45541.1 - 1.3e-25 89.0 0.5 2.2e-25 88.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EMG45541.1 - 6.4e-22 77.8 0.8 9.3e-22 77.3 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain RAI1 PF08652.11 EMG45542.1 - 3.6e-27 94.3 0.5 8.9e-27 93.1 0.5 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF4760 PF15956.5 EMG45542.1 - 0.003 17.7 0.7 0.017 15.3 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4760) Catalase PF00199.19 EMG45543.1 - 1.6e-53 182.2 0.0 1.7e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Catalase LRR_8 PF13855.6 EMG45544.1 - 9.6e-05 22.1 4.6 0.034 13.9 0.1 4.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 EMG45544.1 - 0.037 14.1 0.8 2.2 8.5 0.2 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 EMG45544.1 - 2.1 8.9 27.7 6.9 7.3 6.2 7.9 7 2 1 8 8 8 0 Leucine Rich repeats (2 copies) adh_short PF00106.25 EMG45545.1 - 6.1e-16 58.5 0.0 9.8e-12 44.7 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMG45545.1 - 9.7e-13 48.2 0.0 7.6e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG45545.1 - 4e-10 39.9 0.0 6.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMG45545.1 - 0.003 17.0 0.0 0.0059 16.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMG45545.1 - 0.025 14.0 0.4 0.061 12.7 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMG45545.1 - 0.088 11.9 0.0 0.088 11.9 0.0 2.1 4 0 0 4 4 4 0 RmlD substrate binding domain Ras PF00071.22 EMG45546.1 - 5e-56 188.8 0.0 6.1e-56 188.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG45546.1 - 4.7e-20 72.0 0.0 7.9e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG45546.1 - 1.7e-08 34.1 0.0 2.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 EMG45547.1 - 7.2e-08 32.1 0.1 2.1e-07 30.7 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMG45547.1 - 0.012 15.7 0.0 0.058 13.5 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif RNA_pol_Rpc4 PF05132.14 EMG45547.1 - 4.6 7.6 13.2 2.3 8.7 6.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 STAC2_u1 PF16664.5 EMG45548.1 - 2.2 8.7 10.8 7.9 6.9 10.8 1.9 1 1 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 WD40 PF00400.32 EMG45549.1 - 1.6e-07 31.9 4.1 0.01 16.7 0.1 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG45549.1 - 0.00034 20.9 0.2 2.3 8.6 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BLYB PF05289.11 EMG45549.1 - 0.1 12.8 4.5 0.49 10.6 1.2 3.0 3 0 0 3 3 3 0 Borrelia hemolysin accessory protein DUF5344 PF17279.2 EMG45549.1 - 0.8 10.3 4.6 1.3 9.7 2.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5344) TTRAP PF14203.6 EMG45550.1 - 0.0047 16.9 0.3 1.2 9.1 0.1 3.1 3 0 0 3 3 3 2 Putative tranposon-transfer assisting protein Ribonuc_red_2_N PF08471.10 EMG45550.1 - 0.018 15.2 1.1 0.99 9.6 0.1 2.4 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase Fungal_trans PF04082.18 EMG45552.1 - 1.4e-13 50.5 2.0 2.7e-13 49.6 0.1 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG45552.1 - 2.6e-06 27.4 9.8 4.2e-06 26.8 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC92 PF14916.6 EMG45552.1 - 0.014 15.1 0.4 0.014 15.1 0.4 2.6 2 0 0 2 2 2 0 Coiled-coil domain of unknown function BT1 PF03092.16 EMG45552.1 - 0.04 12.2 0.0 0.067 11.4 0.0 1.2 1 0 0 1 1 1 0 BT1 family CtIP_N PF10482.9 EMG45552.1 - 8.8 6.4 8.7 0.14 12.2 0.9 2.1 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain PAT1 PF09770.9 EMG45553.1 - 0.032 12.5 40.8 0.037 12.3 40.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOG2 PF10428.9 EMG45553.1 - 2.3 7.3 25.9 0.013 14.7 17.2 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein Pkinase PF00069.25 EMG45554.1 - 3.9e-68 229.7 0.0 4.5e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45554.1 - 1.9e-30 106.1 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG45554.1 - 0.00082 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EMG45554.1 - 0.0092 15.9 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DAO PF01266.24 EMG45555.1 - 2.3e-59 201.7 0.0 2.6e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMG45555.1 - 8.3e-08 32.3 0.0 1.9e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EMG45555.1 - 0.00039 20.6 0.1 0.0015 18.8 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_2 PF07992.14 EMG45555.1 - 0.0097 15.2 0.0 0.031 13.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMG45555.1 - 0.012 16.2 0.2 0.027 15.0 0.1 1.6 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EMG45555.1 - 0.018 14.7 0.1 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 EMG45555.1 - 0.023 13.8 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 EMG45555.1 - 0.098 12.5 0.8 0.21 11.5 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EMG45555.1 - 0.14 11.4 2.6 0.11 11.7 0.3 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMG45555.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EMG45555.1 - 0.15 10.7 0.1 0.23 10.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Adaptin_N PF01602.20 EMG45557.1 - 2.8e-76 257.2 18.3 4.1e-76 256.6 18.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 EMG45557.1 - 0.00022 21.2 0.4 0.07 13.4 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat Alpha_adaptin_C PF02296.16 EMG45557.1 - 0.00067 19.8 0.0 0.0031 17.7 0.0 2.2 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Vac14_Fab1_bd PF12755.7 EMG45557.1 - 0.0016 19.0 1.8 0.0044 17.6 0.2 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EMG45557.1 - 0.032 14.6 0.2 0.2 12.1 0.2 2.3 1 1 0 1 1 1 0 HEAT repeats RTP1_C1 PF10363.9 EMG45557.1 - 0.19 11.9 0.9 0.78 9.9 0.5 2.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 SH3_9 PF14604.6 EMG45558.1 - 2.8e-09 36.7 0.1 5.9e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMG45558.1 - 8.5e-09 34.9 0.1 1.6e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMG45558.1 - 4.4e-06 26.3 0.0 8.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain CAP PF00188.26 EMG45559.1 - 2.4e-19 70.4 3.9 2.4e-19 70.4 3.9 2.2 2 0 0 2 2 2 1 Cysteine-rich secretory protein family SOG2 PF10428.9 EMG45559.1 - 9.7 5.3 13.6 11 5.0 13.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Anoctamin PF04547.12 EMG45560.1 - 3e-70 237.3 15.9 4.3e-70 236.8 15.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel La PF05383.17 EMG45561.1 - 1.4e-22 79.5 0.7 5.5e-22 77.6 0.1 2.2 2 0 0 2 2 2 1 La domain Nre_N PF04894.12 EMG45561.1 - 0.0078 16.1 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 Archaeal Nre, N-terminal Ala_racemase_N PF01168.20 EMG45562.1 - 5.2e-27 94.9 0.0 6e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DHQS PF01959.16 EMG45562.1 - 0.063 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 3-dehydroquinate synthase II SMAP PF15477.6 EMG45562.1 - 0.2 12.6 1.0 0.44 11.5 0.2 1.9 1 1 1 2 2 2 0 Small acidic protein family DUF1805 PF08827.11 EMG45563.1 - 0.047 14.0 0.1 0.94 9.9 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF1805) Spt20 PF12090.8 EMG45564.1 - 0.043 13.4 7.5 0.063 12.9 7.5 1.4 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 EMG45564.1 - 0.2 11.6 12.5 0.22 11.5 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLASP_N PF12348.8 EMG45565.1 - 1.5e-84 283.1 9.8 1.5e-81 273.3 1.7 3.0 3 0 0 3 3 3 2 CLASP N terminal Peptidase_C13 PF01650.18 EMG45566.1 - 4.4e-46 157.5 1.1 7.4e-46 156.7 0.3 1.7 2 0 0 2 2 2 1 Peptidase C13 family ResIII PF04851.15 EMG45566.1 - 5.3e-25 88.4 0.3 1.9e-24 86.6 0.2 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMG45566.1 - 3.1e-16 59.7 0.9 1.4e-15 57.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMG45566.1 - 4.8e-13 49.3 0.6 3e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EMG45566.1 - 0.00033 19.9 0.0 0.00095 18.5 0.0 1.8 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 EMG45566.1 - 0.0031 16.8 0.1 0.0059 15.9 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 EMG45566.1 - 0.0051 16.8 0.2 0.011 15.8 0.2 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain TrwB_AAD_bind PF10412.9 EMG45566.1 - 0.028 13.3 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Helicase_C_2 PF13307.6 EMG45566.1 - 0.082 13.1 0.3 1.5 9.0 0.0 2.7 2 0 0 2 2 2 0 Helicase C-terminal domain AAA_11 PF13086.6 EMG45566.1 - 0.11 12.3 1.0 0.67 9.7 0.0 2.4 2 1 1 3 3 3 0 AAA domain Pol_alpha_B_N PF08418.10 EMG45567.1 - 1.4e-43 149.6 9.5 2.3e-43 148.9 9.5 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EMG45567.1 - 1.1e-34 119.7 0.1 1.9e-34 118.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.25 EMG45568.1 - 6.9e-69 232.1 1.2 1.9e-68 230.7 1.2 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45568.1 - 1.6e-31 109.6 0.2 2.4e-30 105.7 0.2 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG45568.1 - 4.1e-05 23.0 0.8 0.18 11.1 0.0 3.1 2 1 0 3 3 3 2 Kinase-like FTA2 PF13095.6 EMG45568.1 - 0.00044 19.9 0.4 0.051 13.2 0.4 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 FeoB_Cyto PF17910.1 EMG45568.1 - 0.027 15.0 0.3 0.12 12.9 0.0 2.3 2 0 0 2 2 2 0 FeoB cytosolic helical domain Kdo PF06293.14 EMG45568.1 - 0.084 12.2 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cwf_Cwc_15 PF04889.12 EMG45568.1 - 1.7 8.3 7.3 5.2 6.7 7.4 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein STE PF02200.16 EMG45569.1 - 4.5e-32 110.7 0.2 2.9e-31 108.1 0.1 2.1 1 1 1 2 2 2 1 STE like transcription factor Glutaredoxin PF00462.24 EMG45570.1 - 2.3e-17 63.0 0.0 5.5e-17 61.7 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin PSY3 PF16836.5 EMG45572.1 - 1.4e-16 60.7 2.6 1.7e-16 60.4 2.6 1.1 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description Imm59 PF15597.6 EMG45572.1 - 0.057 13.9 4.2 0.71 10.4 4.2 2.4 1 1 0 1 1 1 0 Immunity protein 59 Mt_ATP-synt_D PF05873.12 EMG45573.1 - 2.5e-16 59.9 2.8 3.1e-16 59.6 2.8 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Vps51 PF08700.11 EMG45573.1 - 0.23 11.6 3.9 6.8 6.9 0.1 2.4 1 1 1 2 2 2 0 Vps51/Vps67 Skp1 PF01466.19 EMG45574.1 - 3.1e-24 84.8 0.3 3.1e-24 84.8 0.3 1.9 3 0 0 3 3 3 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EMG45574.1 - 3.1e-19 68.9 1.5 4.3e-19 68.5 0.3 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DHH PF01368.20 EMG45574.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.4 1 1 0 1 1 1 0 DHH family CDC45 PF02724.14 EMG45575.1 - 0.24 9.7 19.8 0.41 8.9 19.8 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EMG45575.1 - 0.31 10.3 29.3 0.011 15.1 23.3 1.6 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 EMG45575.1 - 0.99 8.8 27.9 2.3 7.6 27.9 1.6 1 0 0 1 1 1 0 SDA1 DUF1870 PF08965.10 EMG45575.1 - 1.7 8.7 6.1 1.9 8.5 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) Thioredoxin_7 PF13899.6 EMG45576.1 - 1.6e-23 82.6 0.1 3.5e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 EMG45576.1 - 3.6e-10 39.5 0.0 7.6e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Thioredox_DsbH PF03190.15 EMG45576.1 - 0.00018 21.5 0.1 0.00038 20.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 EMG45576.1 - 0.032 14.7 0.1 0.094 13.2 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain Tub_N PF16322.5 EMG45576.1 - 0.18 12.2 8.3 0.022 15.1 2.7 2.1 2 0 0 2 2 2 0 Tubby N-terminal Spt5_N PF11942.8 EMG45576.1 - 2.3 9.2 19.7 0.16 13.0 9.6 2.8 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Pkinase PF00069.25 EMG45577.1 - 9e-49 166.2 0.0 2.5e-48 164.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45577.1 - 5.5e-30 104.5 0.0 1.8e-29 102.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMG45577.1 - 2.8e-06 26.5 0.0 7.5e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EMG45577.1 - 0.032 14.2 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EMG45577.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMG45577.1 - 0.17 11.1 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Peroxin-3 PF04882.12 EMG45578.1 - 1.7e-106 357.1 23.9 5.4e-74 249.9 15.1 2.3 1 1 1 2 2 2 2 Peroxin-3 Npa1 PF11707.8 EMG45579.1 - 1.4e-79 268.0 15.5 1.4e-79 268.0 15.5 2.6 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EMG45579.1 - 2.4e-44 151.4 2.2 2.4e-44 151.4 2.2 3.5 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 GIDA PF01134.22 EMG45580.1 - 1.9e-151 504.6 0.0 2.4e-151 504.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EMG45580.1 - 2e-59 201.3 0.1 3e-59 200.7 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 EMG45580.1 - 0.0004 19.7 4.3 0.0021 17.3 0.2 2.7 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMG45580.1 - 0.056 12.8 0.2 0.056 12.8 0.2 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMG45580.1 - 0.21 10.6 1.4 0.25 10.4 0.5 1.6 2 0 0 2 2 2 0 FAD binding domain CMS1 PF14617.6 EMG45581.1 - 1.6e-20 73.5 28.2 1.1e-17 64.3 28.2 2.9 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EMG45581.1 - 0.021 14.6 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Vps51 PF08700.11 EMG45582.1 - 3.1e-13 49.6 0.7 3.1e-13 49.6 0.7 3.5 3 0 0 3 3 3 1 Vps51/Vps67 Zn_clus PF00172.18 EMG45583.1 - 1.4e-06 28.3 14.1 2.8e-06 27.4 14.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 EMG45583.1 - 1.2 9.7 11.9 3.9 8.0 11.9 1.9 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Menin PF05053.13 EMG45583.1 - 1.8 6.8 8.9 2.3 6.5 8.9 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 EMG45583.1 - 3.5 6.1 14.8 4.2 5.8 14.8 1.1 1 0 0 1 1 1 0 Macoilin family FSA_C PF10479.9 EMG45583.1 - 4.2 5.4 13.4 5.1 5.1 13.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AA_permease PF00324.21 EMG45584.1 - 2e-30 105.9 8.1 2.1e-30 105.8 8.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45584.1 - 8.6e-10 38.0 8.0 9.6e-10 37.8 8.0 1.0 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 EMG45585.1 - 2.3e-63 214.3 0.0 2.7e-62 210.7 0.0 1.9 2 0 0 2 2 2 2 AMP-binding enzyme GATase_6 PF13522.6 EMG45586.1 - 3.5e-13 49.9 0.0 6.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EMG45586.1 - 1.4e-10 41.1 0.0 2.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EMG45586.1 - 2.2e-07 30.5 0.0 3.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EMG45586.1 - 0.0023 16.9 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRKCSH-like PF12999.7 EMG45586.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DNA_photolyase PF00875.18 EMG45586.1 - 0.2 11.6 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 DNA photolyase DEAD PF00270.29 EMG45587.1 - 4.5e-43 147.1 0.0 6.5e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG45587.1 - 1.6e-29 102.5 0.2 4.5e-28 97.8 0.2 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG45587.1 - 0.00055 20.0 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CBFB_NFYA PF02045.15 EMG45588.1 - 7.5e-29 100.1 8.0 1.7e-28 99.0 8.0 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Cse1 PF08506.10 EMG45589.1 - 2.5e-153 510.3 19.9 2.5e-153 510.3 19.9 2.1 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 EMG45589.1 - 4.5e-103 345.1 7.6 1e-102 343.9 7.6 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EMG45589.1 - 3.2e-14 52.6 4.0 6.1e-14 51.7 0.1 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EMG45589.1 - 0.044 13.9 0.2 0.044 13.9 0.2 5.0 2 2 3 5 5 5 0 Exportin 1-like protein DUF3385 PF11865.8 EMG45589.1 - 0.064 13.2 0.1 0.064 13.2 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) RIX1 PF08167.12 EMG45589.1 - 0.17 11.6 9.0 1.9 8.2 0.1 4.7 5 2 1 6 6 6 0 rRNA processing/ribosome biogenesis DUF1796 PF08795.10 EMG45589.1 - 0.55 10.2 2.5 2.3 8.1 0.1 2.7 3 0 0 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) EamA PF00892.20 EMG45590.1 - 0.0079 16.4 34.3 0.0092 16.2 11.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family Borrelia_orfD PF02999.14 EMG45590.1 - 0.1 12.9 2.2 9.4 6.6 0.0 3.3 3 0 0 3 3 3 0 Borrelia orf-D family TraL PF07178.11 EMG45590.1 - 1.1 9.8 7.9 11 6.5 1.2 3.6 2 1 0 3 3 3 0 TraL protein LicD PF04991.13 EMG45591.1 - 5.8e-25 88.8 11.6 8.1e-20 71.9 0.3 3.5 2 1 1 3 3 3 2 LicD family MFS_1 PF07690.16 EMG45592.1 - 1.6e-38 132.6 61.1 3.8e-37 128.0 62.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG45592.1 - 1.4e-07 30.8 21.2 1.4e-07 30.8 21.2 4.0 3 2 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 EMG45592.1 - 0.002 16.6 5.8 0.002 16.6 5.8 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector YMF19 PF02326.15 EMG45592.1 - 0.018 15.8 0.3 0.018 15.8 0.3 3.9 4 1 0 4 4 4 0 Plant ATP synthase F0 DUF2238 PF09997.9 EMG45592.1 - 1.4 8.7 6.6 0.16 11.8 0.4 2.5 2 1 0 3 3 3 0 Predicted membrane protein (DUF2238) DUF2457 PF10446.9 EMG45592.1 - 2 7.5 9.6 2.8 7.0 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Epimerase PF01370.21 EMG45593.1 - 1e-19 71.0 0.0 1.4e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMG45593.1 - 9.4e-13 47.9 0.0 1e-07 31.4 0.0 2.4 3 0 0 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 EMG45593.1 - 4.2e-11 42.4 0.0 5.6e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMG45593.1 - 8.7e-10 38.5 0.1 1e-09 38.3 0.1 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMG45593.1 - 6.2e-07 29.5 0.0 4.4e-06 26.7 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EMG45593.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EMG45593.1 - 0.00011 22.2 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EMG45593.1 - 0.00032 20.3 0.0 0.032 13.8 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EMG45593.1 - 0.0012 18.4 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EMG45593.1 - 0.0026 16.9 0.0 0.015 14.4 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Rep_fac-A_3 PF08661.11 EMG45593.1 - 0.11 12.9 0.0 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 Replication factor A protein 3 DUF1479 PF07350.12 EMG45594.1 - 3.7e-131 437.7 0.0 4.2e-131 437.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DnaJ PF00226.31 EMG45595.1 - 9.8e-10 38.4 0.0 2.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain LRR_8 PF13855.6 EMG45596.1 - 9.5e-06 25.3 12.3 0.00072 19.3 0.0 5.7 7 1 0 7 7 7 2 Leucine rich repeat LRR_4 PF12799.7 EMG45596.1 - 0.00015 22.1 0.0 0.00015 22.1 0.0 7.8 9 1 0 9 9 9 1 Leucine Rich repeats (2 copies) FNIP PF05725.12 EMG45596.1 - 0.0045 17.1 23.5 0.24 11.6 0.0 9.4 7 4 2 9 9 9 1 FNIP Repeat Gal11_ABD1 PF18535.1 EMG45596.1 - 0.15 12.2 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) LRR_1 PF00560.33 EMG45596.1 - 0.73 10.6 12.5 1.1 10.0 0.0 7.4 8 2 0 8 8 8 0 Leucine Rich Repeat GCS PF03074.16 EMG45597.1 - 3.4e-149 497.2 0.1 5.6e-149 496.5 0.1 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase PAP2_3 PF14378.6 EMG45598.1 - 1.7e-15 57.2 18.2 2.3e-15 56.8 18.2 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 EMG45598.1 - 9.4e-14 51.3 8.3 2.1e-13 50.2 8.3 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 EMG45598.1 - 0.26 11.9 12.3 0.051 14.1 7.0 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal GARS_A PF01071.19 EMG45599.1 - 1.7e-81 272.7 0.0 3e-81 271.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EMG45599.1 - 9.6e-35 119.3 1.0 6.9e-34 116.5 0.0 2.9 3 1 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 EMG45599.1 - 4.7e-33 114.5 0.0 1.1e-32 113.3 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EMG45599.1 - 1.8e-23 82.6 0.3 3.8e-23 81.6 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EMG45599.1 - 2.5e-17 63.3 2.1 2.1e-16 60.4 2.7 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 EMG45599.1 - 2.8e-05 23.7 0.0 7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EMG45599.1 - 0.00022 21.3 0.1 0.001 19.1 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EMG45599.1 - 0.0089 15.5 0.1 0.02 14.4 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 EMG45599.1 - 0.057 13.0 1.1 0.38 10.3 0.0 2.7 4 0 0 4 4 4 0 RimK-like ATP-grasp domain Ribonuc_2-5A PF06479.12 EMG45600.1 - 9.6e-45 151.8 2.4 9.6e-45 151.8 2.4 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 EMG45600.1 - 1.3e-40 139.4 0.0 5.9e-40 137.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45600.1 - 3.8e-25 88.6 0.0 1.5e-24 86.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 EMG45600.1 - 0.00016 21.4 0.0 0.53 9.8 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 EMG45600.1 - 0.00034 20.4 0.0 0.92 9.6 0.0 3.0 3 0 0 3 3 3 2 PQQ enzyme repeat Pkinase_fungal PF17667.1 EMG45600.1 - 0.011 14.6 3.5 0.074 11.8 0.0 2.8 2 1 1 3 3 3 0 Fungal protein kinase Kdo PF06293.14 EMG45600.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sas10_Utp3 PF04000.15 EMG45601.1 - 6.8e-12 45.8 0.9 6.8e-12 45.8 0.9 2.0 3 0 0 3 3 3 1 Sas10/Utp3/C1D family DUF3502 PF12010.8 EMG45601.1 - 0.58 10.8 0.1 0.58 10.8 0.1 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF3502) Nop25 PF09805.9 EMG45602.1 - 2.6e-43 147.8 16.6 2.6e-43 147.8 16.6 2.4 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) HAUS6_N PF14661.6 EMG45602.1 - 2.2 7.8 14.2 0.23 11.0 8.3 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus EXS PF03124.14 EMG45603.1 - 4.7e-73 246.4 28.6 5.7e-73 246.1 28.6 1.1 1 0 0 1 1 1 1 EXS family Ribonuclease_3 PF00636.26 EMG45605.1 - 2.1e-07 31.5 0.3 1.4e-06 28.9 0.0 2.4 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EMG45605.1 - 3e-07 30.6 0.1 0.038 14.2 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 EMG45605.1 - 6.6e-07 29.9 0.0 1.8e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif Swi5 PF07061.11 EMG45606.1 - 6.7e-21 74.2 4.6 1e-20 73.6 4.6 1.2 1 0 0 1 1 1 1 Swi5 Nudix_N PF12535.8 EMG45606.1 - 0.058 13.0 0.1 0.092 12.4 0.1 1.4 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal CENP-T_C PF15511.6 EMG45607.1 - 5.8e-10 39.3 0.1 1.1e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EMG45607.1 - 0.00057 20.3 0.3 0.0014 19.1 0.3 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-S PF15630.6 EMG45607.1 - 0.001 19.4 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 EMG45607.1 - 0.019 15.0 0.1 0.043 13.8 0.1 1.6 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 EMG45607.1 - 2.6 8.4 0.0 2.6 8.4 0.0 2.9 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 Mito_carr PF00153.27 EMG45608.1 - 4.1e-27 94.0 7.0 5.1e-11 42.3 0.1 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein zf-C2H2_3 PF13878.6 EMG45609.1 - 5.5e-05 22.9 0.3 0.00011 22.0 0.3 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO KfrB PF18790.1 EMG45609.1 - 0.092 13.0 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 KfrB protein QRPTase_C PF01729.19 EMG45610.1 - 1.4e-57 194.2 0.2 1.9e-57 193.7 0.2 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EMG45610.1 - 4.4e-16 58.7 0.1 2.1e-15 56.5 0.1 2.1 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain ANAPC10 PF03256.16 EMG45611.1 - 1.6e-43 148.6 0.3 3.7e-31 108.2 0.0 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) AIM3 PF17096.5 EMG45611.1 - 6.2 7.8 8.0 5.8 7.9 2.7 2.6 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 SMI1_KNR4 PF09346.10 EMG45612.1 - 4.1e-28 98.4 2.7 7.5e-28 97.6 0.0 2.8 3 1 0 4 4 4 1 SMI1 / KNR4 family (SUKH-1) YtxH PF12732.7 EMG45612.1 - 0.79 10.3 3.3 4.2 8.0 3.3 2.3 1 1 0 1 1 1 0 YtxH-like protein SurE PF01975.17 EMG45613.1 - 1.2e-38 132.8 0.0 1.5e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE VASt PF16016.5 EMG45614.1 - 3.5e-39 134.7 0.4 8.8e-39 133.4 0.4 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EMG45614.1 - 6.4e-30 103.4 0.2 1.7e-29 102.0 0.2 1.8 1 0 0 1 1 1 1 GRAM domain Yos1 PF08571.10 EMG45614.1 - 0.17 12.2 0.0 0.64 10.3 0.0 2.0 1 0 0 1 1 1 0 Yos1-like CYSTM PF12734.7 EMG45614.1 - 0.45 10.9 4.2 0.27 11.6 0.2 2.5 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance DUF1631 PF07793.11 EMG45614.1 - 6.6 5.0 7.9 13 4.0 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) AA_permease PF00324.21 EMG45616.1 - 1.2e-118 396.7 37.2 1.5e-118 396.5 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45616.1 - 5.1e-35 121.1 41.2 6.6e-35 120.7 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease Ammonium_transp PF00909.21 EMG45617.1 - 2.2e-72 244.0 21.7 1.8e-40 138.9 17.0 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family DUF2953 PF11167.8 EMG45617.1 - 0.29 11.2 0.1 0.29 11.2 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2953) Mito_carr PF00153.27 EMG45618.1 - 3.5e-69 228.8 0.3 3.1e-22 78.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SOG2 PF10428.9 EMG45619.1 - 1.4e-52 179.6 14.7 3.1e-33 115.7 5.2 5.6 4 1 1 5 5 5 2 RAM signalling pathway protein LRR_8 PF13855.6 EMG45619.1 - 2.6e-13 49.5 7.1 1.7e-09 37.3 1.8 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EMG45619.1 - 7.1e-10 39.0 15.1 6.7e-05 23.2 0.7 3.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) DUF5312 PF17239.2 EMG45619.1 - 0.23 9.8 8.3 0.018 13.4 0.9 2.7 3 1 1 4 4 4 0 Family of unknown function (DUF5312) LRR_1 PF00560.33 EMG45619.1 - 0.42 11.3 12.0 58 4.8 0.2 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat DLIC PF05783.11 EMG45619.1 - 0.57 8.9 9.6 1.1 8.0 9.6 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) HMA PF00403.26 EMG45620.1 - 8.6e-13 48.5 0.0 1.9e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF3419 PF11899.8 EMG45621.1 - 2.2e-149 497.9 0.0 6.9e-149 496.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.6 EMG45621.1 - 9.1e-11 41.8 0.0 1.4e-09 38.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG45621.1 - 1.4e-10 41.7 0.0 2.4e-09 37.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG45621.1 - 3.4e-10 40.6 0.0 2e-09 38.1 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG45621.1 - 4.6e-10 40.0 0.0 1.6e-08 35.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMG45621.1 - 6e-10 39.2 0.0 5.1e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMG45621.1 - 2.1e-08 33.8 0.1 3.7e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Rsm22 PF09243.10 EMG45621.1 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 PCMT PF01135.19 EMG45621.1 - 0.0092 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.17 EMG45621.1 - 0.02 14.5 0.0 0.059 13.0 0.0 1.8 2 1 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CM_2 PF01817.21 EMG45622.1 - 0.00069 19.9 0.0 0.43 11.0 0.0 2.6 2 1 0 2 2 2 2 Chorismate mutase type II UEV PF05743.13 EMG45623.1 - 4.5e-27 94.3 1.1 8.1e-27 93.5 1.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EMG45623.1 - 4e-18 65.1 0.1 4.5e-17 61.8 0.0 2.3 2 0 0 2 2 2 1 Vps23 core domain phiKZ_IP PF12699.7 EMG45623.1 - 0.064 12.4 0.2 0.17 11.0 0.1 1.5 1 1 1 2 2 2 0 phiKZ-like phage internal head proteins Laminin_II PF06009.12 EMG45623.1 - 0.078 13.0 2.5 0.51 10.4 2.3 2.0 2 0 0 2 2 2 0 Laminin Domain II ATP_synt_H PF05493.13 EMG45624.1 - 1.8e-21 76.3 1.5 2e-21 76.2 1.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Git3 PF11710.8 EMG45624.1 - 0.0035 17.2 0.4 0.0035 17.1 0.4 1.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 EMG45624.1 - 0.006 15.7 1.0 0.0065 15.6 1.0 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF4131 PF13567.6 EMG45624.1 - 0.0073 16.0 0.6 0.0073 16.0 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) TMEM220 PF15071.6 EMG45624.1 - 0.033 14.9 0.3 0.035 14.9 0.3 1.2 1 0 0 1 1 1 0 Transmembrane family 220, helix FixQ PF05545.11 EMG45624.1 - 0.075 13.0 0.2 0.075 13.0 0.2 1.9 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ PhoR PF11808.8 EMG45624.1 - 5.1 7.6 7.6 26 5.3 7.6 1.8 1 1 0 1 1 1 0 Phosphate regulon sensor protein PhoR CAP PF00188.26 EMG45625.1 - 4.1e-16 60.0 5.9 6.8e-16 59.2 5.9 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PsbR PF04725.12 EMG45625.1 - 0.05 13.9 0.7 0.095 13.1 0.7 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR AA_permease PF00324.21 EMG45626.1 - 3.4e-42 144.6 9.5 3.7e-42 144.5 9.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45626.1 - 2.5e-20 72.7 9.5 2.8e-20 72.6 9.5 1.0 1 0 0 1 1 1 1 Amino acid permease Importin_rep_5 PF18816.1 EMG45627.1 - 1.1e-25 89.6 0.3 2.1e-25 88.8 0.3 1.5 1 0 0 1 1 1 1 Importin repeat FANCI_S1 PF14675.6 EMG45627.1 - 0.078 12.5 0.1 1.8 8.1 0.0 2.0 2 0 0 2 2 2 0 FANCI solenoid 1 AIP3 PF03915.13 EMG45628.1 - 1.2e-137 459.4 12.7 2.2e-137 458.5 12.7 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 Syntaxin_2 PF14523.6 EMG45628.1 - 0.017 15.5 19.2 0.022 15.1 0.0 5.1 3 1 3 6 6 6 0 Syntaxin-like protein DUF3823_C PF18003.1 EMG45628.1 - 0.092 13.5 1.9 0.27 12.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3823_C) DUF1476 PF07345.11 EMG45628.1 - 0.24 11.8 2.8 0.52 10.7 0.3 2.9 3 0 0 3 3 3 0 ATPase inhibitor subunit zeta TMPIT PF07851.13 EMG45628.1 - 2 7.6 11.0 1.8 7.8 1.1 3.2 2 1 1 3 3 3 0 TMPIT-like protein CorA PF01544.18 EMG45628.1 - 3.7 6.8 14.5 0.023 14.0 3.4 2.9 3 2 1 4 4 4 0 CorA-like Mg2+ transporter protein Telomerase_RBD PF12009.8 EMG45629.1 - 1.3e-27 96.6 1.5 2.7e-27 95.5 0.2 2.4 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EMG45629.1 - 2.9e-09 36.8 11.1 1.4e-08 34.6 2.9 3.1 2 1 2 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) dCMP_cyt_deam_1 PF00383.23 EMG45630.1 - 3.1e-08 33.4 0.6 4.6e-08 32.9 0.6 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMG45630.1 - 2e-05 24.4 0.0 3.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EMG45630.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase Radical_SAM_N PF08497.10 EMG45630.1 - 0.14 11.4 0.2 0.2 10.8 0.2 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal Drf_FH3 PF06367.16 EMG45630.1 - 0.27 10.8 3.2 0.1 12.2 0.7 1.5 2 0 0 2 2 2 0 Diaphanous FH3 Domain SNF5 PF04855.12 EMG45631.1 - 4.1e-49 167.5 1.9 9.5e-30 104.1 0.3 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 LtrA PF06772.11 EMG45632.1 - 1.1e-34 120.3 20.3 1.6e-34 119.7 20.3 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) HIT PF01230.23 EMG45633.1 - 1.1e-24 87.0 0.2 1.6e-24 86.5 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EMG45633.1 - 2.1e-12 47.5 0.4 9.6e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EMG45633.1 - 0.02 14.8 0.8 0.043 13.7 0.8 1.7 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 PSII_Pbs27 PF13326.6 EMG45633.1 - 0.048 14.0 0.0 0.068 13.5 0.0 1.3 1 0 0 1 1 1 0 Photosystem II Pbs27 EVE PF01878.18 EMG45633.1 - 0.062 13.3 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 EVE domain AAA PF00004.29 EMG45634.1 - 8.5e-98 323.9 0.0 5.9e-48 162.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMG45634.1 - 2.7e-25 87.9 2.9 7e-13 48.2 0.6 3.0 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EMG45634.1 - 4.6e-19 68.4 2.0 9.7e-19 67.3 0.5 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 EMG45634.1 - 2.2e-14 53.9 0.1 1.7e-07 31.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EMG45634.1 - 6.6e-14 51.9 0.0 5.4e-06 26.2 0.0 3.0 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EMG45634.1 - 1.5e-11 44.7 0.0 7.7e-06 26.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.17 EMG45634.1 - 3e-11 42.9 0.0 8.5e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 EMG45634.1 - 3.3e-11 43.9 0.0 0.001 19.5 0.0 4.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EMG45634.1 - 8e-11 42.1 0.6 1.9e-05 24.7 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EMG45634.1 - 3.6e-09 36.3 5.3 0.0011 18.2 0.0 3.7 4 0 0 4 4 4 2 TIP49 P-loop domain AAA_22 PF13401.6 EMG45634.1 - 1.3e-08 35.2 2.7 0.06 13.6 0.0 4.8 3 2 1 4 4 4 2 AAA domain AAA_14 PF13173.6 EMG45634.1 - 1.8e-07 31.2 0.0 0.0081 16.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 EMG45634.1 - 2.1e-07 31.3 0.0 0.036 14.5 0.0 3.8 4 0 0 4 4 3 2 RNA helicase IstB_IS21 PF01695.17 EMG45634.1 - 3.1e-07 30.3 0.1 0.018 14.8 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EMG45634.1 - 5.4e-07 29.2 0.6 0.032 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EMG45634.1 - 2.6e-06 27.0 0.6 0.46 9.8 0.1 3.8 3 0 0 3 3 3 2 KaiC AAA_18 PF13238.6 EMG45634.1 - 4.8e-06 27.2 0.0 0.18 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EMG45634.1 - 7.4e-06 25.9 1.5 2.8e-05 24.0 0.1 2.6 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.18 EMG45634.1 - 1.4e-05 25.1 0.4 0.01 15.7 0.0 3.2 4 0 0 4 4 3 1 Bacterial dnaA protein ABC_tran PF00005.27 EMG45634.1 - 1.7e-05 25.3 0.3 0.19 12.2 0.0 4.0 4 1 0 4 4 2 1 ABC transporter AAA_7 PF12775.7 EMG45634.1 - 2.1e-05 24.1 0.2 0.13 11.8 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 EMG45634.1 - 3.4e-05 23.7 0.1 0.065 13.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EMG45634.1 - 4e-05 23.4 0.1 0.25 11.0 0.0 3.4 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 EMG45634.1 - 6.4e-05 22.6 5.9 1.2 8.6 0.2 4.3 2 2 2 4 4 4 1 AAA domain AAA_17 PF13207.6 EMG45634.1 - 7.7e-05 23.1 0.1 0.36 11.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EMG45634.1 - 7.8e-05 23.0 0.0 0.47 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EMG45634.1 - 9.8e-05 22.4 0.0 0.038 14.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 EMG45634.1 - 0.00012 21.3 0.2 0.42 9.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 EMG45634.1 - 0.00027 20.2 0.0 0.26 10.4 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.11 EMG45634.1 - 0.00037 20.4 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EMG45634.1 - 0.00041 20.3 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EMG45634.1 - 0.00048 19.6 3.4 0.12 11.8 0.1 2.7 3 0 0 3 3 2 2 PhoH-like protein AAA_11 PF13086.6 EMG45634.1 - 0.002 17.9 2.0 1.5 8.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EMG45634.1 - 0.0021 17.8 0.5 2.6 7.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 EMG45634.1 - 0.0031 16.8 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EMG45634.1 - 0.0036 17.2 0.2 5.8 6.8 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_19 PF13245.6 EMG45634.1 - 0.0045 17.3 1.0 4.5 7.6 0.0 3.5 3 1 0 4 4 2 0 AAA domain Zeta_toxin PF06414.12 EMG45634.1 - 0.0046 16.3 0.1 1.6 7.9 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin IPT PF01745.16 EMG45634.1 - 0.017 14.5 0.2 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.15 EMG45634.1 - 0.032 14.1 1.7 8.4 6.3 0.0 4.2 4 0 0 4 4 4 0 NTPase NB-ARC PF00931.22 EMG45634.1 - 0.037 13.2 0.5 7.7 5.6 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Sigma54_activ_2 PF14532.6 EMG45634.1 - 0.04 14.0 0.0 5.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 EMG45634.1 - 0.046 13.5 0.7 9.9 5.8 0.0 3.0 3 0 0 3 3 2 0 Cytidylate kinase T2SSE PF00437.20 EMG45634.1 - 0.05 12.7 0.0 7.8 5.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein SRPRB PF09439.10 EMG45634.1 - 0.063 12.7 0.3 22 4.4 0.1 3.7 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit KAP_NTPase PF07693.14 EMG45634.1 - 0.068 12.4 0.0 2.6 7.2 0.0 2.7 2 1 1 3 3 3 0 KAP family P-loop domain Viral_helicase1 PF01443.18 EMG45634.1 - 0.1 12.3 0.0 17 5.1 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_6 PF12774.7 EMG45634.1 - 0.33 9.9 0.8 9.5 5.1 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region ATPase_2 PF01637.18 EMG45634.1 - 0.34 10.8 7.4 1.7 8.5 0.1 4.3 4 1 1 5 5 4 0 ATPase domain predominantly from Archaea AA_permease PF00324.21 EMG45635.1 - 1.1e-31 110.0 7.2 1.2e-31 109.9 7.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45635.1 - 1.9e-07 30.3 4.9 2.1e-07 30.1 4.9 1.0 1 0 0 1 1 1 1 Amino acid permease Importin_rep_6 PF18829.1 EMG45636.1 - 7.8e-33 112.8 2.5 7.8e-33 112.8 2.5 3.3 4 0 0 4 4 3 1 Importin repeat 6 Importin_rep_4 PF18808.1 EMG45636.1 - 1.1e-29 102.6 13.1 1.9e-29 101.8 0.9 5.0 5 1 0 5 5 5 1 Importin repeat HEAT_EZ PF13513.6 EMG45636.1 - 3.7e-22 78.4 19.2 2.8e-13 50.1 0.2 9.1 8 3 3 11 11 11 4 HEAT-like repeat HEAT_2 PF13646.6 EMG45636.1 - 1.4e-18 67.1 4.2 2.9e-08 34.0 0.3 7.0 2 2 5 7 7 7 4 HEAT repeats HEAT PF02985.22 EMG45636.1 - 1.4e-14 52.9 17.2 0.00069 19.7 0.0 10.2 11 0 0 11 11 9 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EMG45636.1 - 1e-10 42.1 0.3 0.0034 18.0 0.0 5.9 3 2 3 6 6 6 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EMG45636.1 - 1.1e-10 41.2 9.4 5.3e-05 22.5 3.2 4.5 3 1 1 4 4 4 3 RNAPII transcription regulator C-terminal RIX1 PF08167.12 EMG45636.1 - 6.7e-08 32.5 1.4 0.0005 19.9 0.2 3.9 2 2 1 3 3 3 2 rRNA processing/ribosome biogenesis ParcG PF10274.9 EMG45636.1 - 1.4e-06 28.6 2.1 0.11 12.7 0.0 4.9 3 2 1 5 5 5 1 Parkin co-regulated protein Cnd1 PF12717.7 EMG45636.1 - 6.4e-06 26.3 0.8 0.072 13.1 0.7 3.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 EMG45636.1 - 6.6e-06 26.1 0.1 0.38 10.6 0.2 5.3 6 1 0 6 6 6 1 Domain of unknown function (DUF3385) RNA_pol_Rpb2_2 PF04561.14 EMG45636.1 - 5.1e-05 23.0 0.1 0.00013 21.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 CLASP_N PF12348.8 EMG45636.1 - 6.5e-05 22.6 0.3 0.91 9.0 0.0 3.7 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.23 EMG45636.1 - 0.0002 21.3 4.6 11 6.2 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.11 EMG45636.1 - 0.00038 20.3 0.1 0.0035 17.1 0.0 2.6 2 0 0 2 2 2 1 DNA alkylation repair enzyme IFRD PF05004.13 EMG45636.1 - 0.0014 17.8 6.4 0.03 13.4 0.4 3.7 2 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 EMG45636.1 - 0.0015 18.7 2.8 3.9 7.7 0.0 3.9 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 CAS_CSE1 PF03378.15 EMG45636.1 - 0.013 14.0 0.1 4.6 5.6 0.2 3.7 3 1 0 4 4 4 0 CAS/CSE protein, C-terminus Ecm29 PF13001.7 EMG45636.1 - 0.044 12.5 2.8 3.9 6.1 0.0 3.2 1 1 2 3 3 3 0 Proteasome stabiliser SNF2_N PF00176.23 EMG45637.1 - 1.1e-73 248.0 0.5 2.3e-73 247.0 0.5 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EMG45637.1 - 5.9e-41 139.1 1.0 5.9e-41 139.1 1.0 3.3 4 0 0 4 4 4 1 SLIDE HAND PF09110.11 EMG45637.1 - 5.3e-32 110.9 3.3 5.3e-32 110.9 3.3 3.7 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 EMG45637.1 - 1.7e-20 73.4 0.3 3.9e-19 69.0 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG45637.1 - 1.8e-10 41.1 0.0 1.8e-10 41.1 0.0 3.8 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMG45637.1 - 8.2e-05 22.4 0.0 0.00024 20.9 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 EMG45637.1 - 0.0019 18.4 1.0 0.95 9.7 0.0 3.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain DEAD_2 PF06733.15 EMG45637.1 - 0.0043 16.7 0.5 0.014 15.0 0.1 2.0 2 0 0 2 2 2 1 DEAD_2 DUF1086 PF06461.11 EMG45637.1 - 0.016 15.0 0.5 0.016 15.0 0.5 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1086) Sec8_exocyst PF04048.14 EMG45637.1 - 0.067 13.1 0.1 0.067 13.1 0.1 2.4 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain AAA_14 PF13173.6 EMG45637.1 - 0.53 10.3 4.7 0.29 11.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 EMG45638.1 - 4e-33 114.6 0.0 4e-33 114.6 0.0 3.0 4 1 0 4 4 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EMG45638.1 - 2.9e-21 75.6 0.0 1.1e-20 73.7 0.0 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EMG45638.1 - 1.6e-11 44.4 10.3 3.7e-08 33.6 0.0 4.3 5 0 0 5 5 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMG45638.1 - 2.2e-06 27.7 3.3 5.1e-06 26.5 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EMG45638.1 - 5.6e-05 23.0 0.1 0.00024 20.9 0.1 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 EMG45638.1 - 0.00051 20.3 0.0 0.00051 20.3 0.0 2.0 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EMG45638.1 - 0.0012 18.9 0.2 0.0012 18.9 0.2 4.2 3 1 0 4 4 2 1 Dynamin family ATP_bind_1 PF03029.17 EMG45638.1 - 0.0077 16.0 0.0 0.0077 16.0 0.0 3.1 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EMG45638.1 - 0.0094 15.5 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.6 EMG45638.1 - 0.058 13.7 2.8 1.3 9.3 0.4 3.8 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EMG45638.1 - 1.6 8.6 9.7 0.08 12.8 0.7 3.0 3 1 0 3 3 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EMG45639.1 - 2e-39 133.9 0.8 6.2e-39 132.3 0.3 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EMG45639.1 - 8e-23 80.3 0.0 1.6e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EMG45639.1 - 9.8e-22 77.2 0.2 5.7e-21 74.7 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMG45639.1 - 5.6e-10 39.0 0.1 1.3e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EMG45639.1 - 0.0072 15.9 0.7 0.79 9.2 0.2 3.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EMG45639.1 - 0.0076 16.3 0.4 4.2 7.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 EMG45639.1 - 0.011 14.7 1.1 0.015 14.3 0.3 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EMG45639.1 - 0.11 12.8 0.1 8.7 6.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 EMG45639.1 - 0.11 12.0 0.9 0.56 9.6 0.1 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EMG45639.1 - 0.11 12.3 3.1 2.3 8.1 0.3 3.1 2 2 1 3 3 3 0 RsgA GTPase Roc PF08477.13 EMG45639.1 - 0.16 12.2 0.3 5 7.4 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase zf-RanBP PF00641.18 EMG45640.1 - 1.6e-14 52.9 13.2 6.6e-09 34.9 2.1 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.24 EMG45640.1 - 6.2e-09 36.6 0.0 1.3e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 EMG45640.1 - 7.4e-09 35.3 0.0 0.00085 19.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vps36-NZF-N PF16988.5 EMG45640.1 - 0.16 11.4 10.7 2.7 7.5 6.1 3.6 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain CobT PF06213.12 EMG45640.1 - 2.9 7.2 17.6 6.1 6.1 17.6 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Glycos_transf_2 PF00535.26 EMG45641.1 - 8.6e-34 116.8 0.0 1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMG45641.1 - 3.6e-12 46.7 0.0 4.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EMG45641.1 - 9e-05 22.1 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EMG45641.1 - 0.00087 18.8 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.6 EMG45641.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 ThiF PF00899.21 EMG45642.1 - 5.6e-60 202.7 0.0 8.4e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EMG45642.1 - 1.8e-08 34.6 4.2 9.2e-05 22.5 0.2 2.3 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 EMG45642.1 - 0.0039 17.2 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF2405 PF10293.9 EMG45642.1 - 0.074 13.0 0.1 0.58 10.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2405) Pyr_redox PF00070.27 EMG45642.1 - 0.14 12.7 0.0 0.53 10.9 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L18p PF00861.22 EMG45642.1 - 0.18 12.2 0.0 0.76 10.2 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Profilin PF00235.19 EMG45643.1 - 3.2e-48 163.2 0.2 3.6e-48 163.0 0.2 1.0 1 0 0 1 1 1 1 Profilin YCII PF03795.14 EMG45645.1 - 0.052 13.9 0.0 0.16 12.4 0.0 1.7 1 1 0 1 1 1 0 YCII-related domain ABC2_membrane PF01061.24 EMG45646.1 - 1.9e-77 259.5 51.6 2.8e-41 141.3 18.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EMG45646.1 - 9.2e-42 142.8 0.0 1.5e-19 70.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EMG45646.1 - 3.2e-32 110.3 1.5 1.6e-30 104.8 0.1 3.1 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.6 EMG45646.1 - 1.5e-15 57.6 0.1 6.4e-15 55.5 0.0 2.2 2 0 0 2 2 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EMG45646.1 - 8.6e-08 32.3 0.0 1.2e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EMG45646.1 - 2.2e-06 27.4 1.0 0.00024 20.8 0.1 2.8 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 EMG45646.1 - 8.4e-05 21.8 38.1 0.00049 19.3 9.9 3.0 3 1 0 3 3 2 2 ABC-2 family transporter protein AAA_22 PF13401.6 EMG45646.1 - 0.00013 22.3 0.1 0.068 13.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 EMG45646.1 - 0.00018 21.2 2.1 0.007 16.1 0.3 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EMG45646.1 - 0.0002 21.2 0.0 0.16 11.8 0.0 2.8 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EMG45646.1 - 0.00028 20.8 0.0 0.099 12.6 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 EMG45646.1 - 0.00035 21.0 0.1 0.0033 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EMG45646.1 - 0.00051 19.5 0.0 0.12 11.8 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EMG45646.1 - 0.0015 18.3 0.1 0.31 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMG45646.1 - 0.0017 18.5 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMG45646.1 - 0.0017 18.6 0.1 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EMG45646.1 - 0.0018 18.8 8.1 0.017 15.7 0.1 4.3 4 2 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.23 EMG45646.1 - 0.0019 18.3 0.3 0.15 12.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EMG45646.1 - 0.0025 18.4 0.3 0.035 14.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 EMG45646.1 - 0.021 14.4 2.4 0.67 9.5 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 EMG45646.1 - 0.041 13.8 0.1 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 EMG45646.1 - 0.059 13.1 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMG45646.1 - 0.062 13.7 0.1 4.1 7.9 0.0 3.3 3 0 0 3 3 2 0 RNA helicase NTPase_1 PF03266.15 EMG45646.1 - 0.07 13.0 0.3 1.8 8.5 0.0 2.9 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 EMG45646.1 - 0.073 12.3 0.2 1.2 8.4 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin SieB PF14163.6 EMG45646.1 - 0.63 9.5 3.6 18 4.8 0.2 3.2 2 0 0 2 2 2 0 Super-infection exclusion protein B GRIM-19 PF06212.12 EMG45647.1 - 7.9e-23 80.9 0.1 8.8e-23 80.7 0.1 1.1 1 0 0 1 1 1 1 GRIM-19 protein zf-C2H2 PF00096.26 EMG45648.1 - 6e-07 29.6 21.7 2.6e-05 24.4 0.2 4.7 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG45648.1 - 0.01 16.6 0.2 0.01 16.6 0.2 4.2 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EMG45648.1 - 0.019 15.1 3.8 0.019 15.1 3.8 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 EMG45648.1 - 0.059 13.1 0.1 0.059 13.1 0.1 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type MTHFR_C PF12225.8 EMG45648.1 - 0.062 12.9 1.1 0.11 12.1 0.5 1.8 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal FOXP-CC PF16159.5 EMG45648.1 - 3.5 8.3 8.1 3.1 8.5 0.0 3.3 2 1 1 3 3 3 0 FOXP coiled-coil domain ERCC4 PF02732.15 EMG45649.1 - 0.082 13.1 0.4 0.11 12.7 0.4 1.2 1 0 0 1 1 1 0 ERCC4 domain TFIIA PF03153.13 EMG45649.1 - 0.12 12.4 9.0 0.12 12.3 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ac110_PIF PF07280.11 EMG45649.1 - 0.81 9.5 3.5 1.9 8.3 3.5 1.6 1 0 0 1 1 1 0 Per os infectivity factor AC110 Cry1Ac_D5 PF17997.1 EMG45650.1 - 0.15 11.9 0.6 0.75 9.6 0.1 1.9 1 1 1 2 2 2 0 Insecticidal delta-endotoxin CryIA(c) domain 5 GTP_EFTU PF00009.27 EMG45652.1 - 1.3e-40 139.1 0.0 2.3e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EMG45652.1 - 3.7e-15 55.7 0.1 2.1e-14 53.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 EMG45652.1 - 7.7e-13 48.3 0.0 2.3e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EMG45652.1 - 1.9e-06 28.2 0.0 4.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 EMG45652.1 - 0.00078 19.2 0.0 0.0022 17.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV Zn_clus PF00172.18 EMG45655.1 - 2.4e-06 27.5 11.0 3.8e-06 26.9 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EMG45655.1 - 3e-06 27.2 0.0 5.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EMG45655.1 - 0.024 14.9 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain DsbD PF02683.15 EMG45655.1 - 0.036 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region PAS_3 PF08447.12 EMG45655.1 - 0.053 13.8 0.0 0.28 11.5 0.0 2.2 3 0 0 3 3 3 0 PAS fold DoxD PF04173.13 EMG45656.1 - 0.042 13.8 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 TQO small subunit DoxD RNase_T PF00929.24 EMG45657.1 - 2.1e-05 25.2 0.0 4.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EMG45657.1 - 0.024 14.4 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 3'-5' exonuclease DUF3591 PF12157.8 EMG45658.1 - 1.5e-175 584.1 6.3 1.5e-175 584.1 6.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) W2 PF02020.18 EMG45659.1 - 4.2e-16 58.9 3.9 4.2e-16 58.9 3.9 1.7 1 1 1 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EMG45660.1 - 4.1e-09 35.8 15.7 0.00048 19.7 0.3 3.6 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMG45660.1 - 1.8e-06 27.6 10.7 0.0075 16.0 1.1 3.2 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EMG45660.1 - 0.068 12.1 0.1 0.084 11.8 0.1 1.3 1 0 0 1 1 1 0 L-fucokinase DUF2726 PF10881.8 EMG45661.1 - 0.035 14.0 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Fungal_trans_2 PF11951.8 EMG45662.1 - 7.4e-59 199.5 7.2 9.8e-59 199.1 7.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG45662.1 - 1e-08 35.2 9.1 2e-08 34.2 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4888 PF16229.5 EMG45663.1 - 0.43 10.5 3.5 1.8 8.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4888) Hydrolase_6 PF13344.6 EMG45664.1 - 1.1e-29 102.5 0.0 1.8e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMG45664.1 - 1.1e-15 57.5 0.0 2.3e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EMG45664.1 - 1.7e-07 31.8 0.0 3.3e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMG45664.1 - 0.0015 18.6 1.1 0.7 10.0 0.0 2.5 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hpt PF01627.23 EMG45665.1 - 1.2e-10 41.5 0.1 2.8e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 Hpt domain NADPH_Ox PF08414.10 EMG45665.1 - 0.0054 17.0 0.2 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 Respiratory burst NADPH oxidase Lipase_3 PF01764.25 EMG45665.1 - 0.095 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Glyco_transf_22 PF03901.17 EMG45666.1 - 3.3e-75 253.9 26.2 3.7e-75 253.7 26.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family zf-primase PF09329.11 EMG45667.1 - 3.4e-14 52.4 0.7 7.6e-14 51.3 0.7 1.6 1 0 0 1 1 1 1 Primase zinc finger Helicase_IV_N PF12462.8 EMG45667.1 - 0.023 14.7 2.3 0.069 13.1 2.3 1.9 1 1 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Sec34 PF04136.15 EMG45668.1 - 1.7e-40 138.3 10.5 1.7e-40 138.3 10.5 2.4 3 0 0 3 3 3 1 Sec34-like family DUF948 PF06103.11 EMG45668.1 - 0.025 14.9 3.6 0.057 13.7 1.8 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FKS1_dom1 PF14288.6 EMG45668.1 - 0.095 13.0 0.1 0.095 13.0 0.1 3.0 3 1 1 4 4 4 0 1,3-beta-glucan synthase subunit FKS1, domain-1 PolC_DP2 PF03833.13 EMG45668.1 - 0.14 10.0 0.3 0.24 9.2 0.3 1.3 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ctr PF04145.15 EMG45669.1 - 1e-22 81.4 19.9 3.6e-21 76.3 19.9 2.1 1 1 0 1 1 1 1 Ctr copper transporter family AA_permease PF00324.21 EMG45672.1 - 1.6e-132 442.5 45.2 2e-132 442.2 45.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45672.1 - 3.1e-39 135.0 46.8 4e-39 134.7 46.8 1.1 1 0 0 1 1 1 1 Amino acid permease FAM195 PF14799.6 EMG45672.1 - 0.017 15.5 0.3 0.039 14.3 0.3 1.5 1 0 0 1 1 1 0 FAM195 family Epimerase PF01370.21 EMG45673.1 - 1.6e-21 76.9 0.0 2.1e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMG45673.1 - 1.1e-13 50.9 0.0 1.1e-11 44.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EMG45673.1 - 2.1e-13 49.9 0.0 2.6e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMG45673.1 - 1.8e-10 40.7 0.0 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMG45673.1 - 1.5e-08 34.7 0.0 7.5e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EMG45673.1 - 2.9e-05 23.4 0.0 6.8e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EMG45673.1 - 5.1e-05 23.0 0.0 0.0089 15.6 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family KR PF08659.10 EMG45673.1 - 0.00016 21.6 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EMG45673.1 - 0.00047 19.7 0.1 0.0028 17.1 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EMG45673.1 - 0.00076 18.7 0.0 0.0042 16.2 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Sigma54_activ_2 PF14532.6 EMG45673.1 - 0.057 13.5 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DapB_N PF01113.20 EMG45673.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.16 EMG45674.1 - 3.7e-34 118.2 43.6 2.4e-28 99.1 20.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMG45674.1 - 1.1e-06 27.8 20.1 0.00081 18.4 6.2 2.1 2 0 0 2 2 2 2 MFS_1 like family ATG22 PF11700.8 EMG45674.1 - 3.1e-06 26.1 16.7 0.0018 17.0 0.7 3.6 3 1 1 4 4 4 3 Vacuole effluxer Atg22 like Sugar_tr PF00083.24 EMG45674.1 - 0.65 8.8 29.2 3.1 6.6 27.0 2.9 1 1 0 1 1 1 0 Sugar (and other) transporter OATP PF03137.20 EMG45674.1 - 1.3 7.3 16.9 1.8 6.8 3.6 3.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 EMG45675.1 - 2.7e-44 151.5 51.7 5.2e-41 140.7 54.6 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMG45675.1 - 1.3e-18 66.8 9.9 1.3e-18 66.8 9.9 2.0 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMG45675.1 - 6.6e-10 38.4 15.5 6.6e-10 38.4 15.5 3.4 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 EMG45675.1 - 1.6 7.0 16.0 0.021 13.2 6.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DAD PF02109.16 EMG45675.1 - 2.5 8.5 8.7 3.3 8.1 2.1 3.5 3 1 0 3 3 3 0 DAD family NTP_transferase PF00483.23 EMG45676.1 - 1.3e-09 38.1 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EMG45676.1 - 0.0018 18.6 0.0 0.003 17.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2726 PF10881.8 EMG45676.1 - 0.083 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Hexapep PF00132.24 EMG45677.1 - 5.1e-10 38.7 15.5 8.6e-05 22.1 3.7 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMG45677.1 - 9.6e-07 28.5 10.7 0.01 15.6 1.0 3.2 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EMG45677.1 - 0.023 13.7 0.8 0.032 13.2 0.8 1.4 1 1 0 1 1 1 0 L-fucokinase DUF4954 PF16314.5 EMG45677.1 - 0.092 10.9 3.9 0.13 10.4 3.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) W2 PF02020.18 EMG45678.1 - 3.8e-17 62.2 3.8 3.8e-17 62.2 3.8 1.7 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon CBS PF00571.28 EMG45679.1 - 7.3e-23 80.8 2.4 2.2e-07 31.2 0.0 5.4 5 0 0 5 5 5 5 CBS domain FA_desaturase PF00487.24 EMG45680.1 - 1.5e-14 54.5 20.9 1.5e-14 54.5 20.9 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EMG45680.1 - 5.8e-12 45.6 0.0 1.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PX PF00787.24 EMG45682.1 - 2.1e-24 85.7 0.2 2.6e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 PX domain ADH_N PF08240.12 EMG45683.1 - 5.3e-30 103.5 0.2 1.1e-29 102.5 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMG45683.1 - 1.6e-27 96.1 1.0 2.6e-27 95.4 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMG45683.1 - 7.3e-07 30.3 0.0 1.4e-06 29.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMG45683.1 - 0.0077 15.7 0.3 0.012 15.0 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EMG45683.1 - 0.083 12.3 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 EMG45684.1 - 6.7e-30 103.2 0.4 1.2e-29 102.4 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMG45684.1 - 7.6e-28 97.1 0.6 1.5e-27 96.1 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMG45684.1 - 2.1e-07 32.1 0.0 3.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMG45684.1 - 0.018 14.5 0.3 0.028 13.9 0.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TFX_C PF14601.6 EMG45684.1 - 0.093 12.7 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term Epimerase PF01370.21 EMG45684.1 - 0.16 11.4 0.2 0.22 10.9 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SE PF08491.10 EMG45685.1 - 2.8e-119 397.3 0.0 3.5e-119 396.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EMG45685.1 - 7.1e-12 45.2 0.0 2.9e-05 23.5 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EMG45685.1 - 7.3e-10 39.0 0.2 5.2e-05 23.0 0.1 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMG45685.1 - 0.00021 21.4 0.1 0.00048 20.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EMG45685.1 - 0.0005 20.0 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMG45685.1 - 0.00081 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EMG45685.1 - 0.00094 19.7 0.0 0.046 14.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMG45685.1 - 0.01 14.9 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EMG45685.1 - 0.015 14.6 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EMG45685.1 - 0.022 14.0 0.0 0.052 12.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMG45685.1 - 0.042 12.9 0.2 0.33 10.0 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 EMG45685.1 - 0.045 13.4 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EMG45685.1 - 0.06 13.6 0.2 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EMG45685.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 EMG45685.1 - 0.095 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 EMG45685.1 - 0.1 11.8 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMG45685.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 EMG45685.1 - 0.13 12.9 0.1 0.32 11.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EMG45685.1 - 0.15 11.7 0.1 0.33 10.5 0.0 1.7 2 0 0 2 2 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GDI PF00996.18 EMG45685.1 - 0.17 10.4 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor HI0933_like PF03486.14 EMG45685.1 - 0.18 10.5 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Zn_clus PF00172.18 EMG45688.1 - 2.7e-06 27.4 4.2 7.3e-06 26.0 4.2 1.7 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Candida_ALS_N PF11766.8 EMG45689.1 - 3.9e-80 268.7 1.3 9e-80 267.5 1.3 1.6 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Candida_ALS PF05792.13 EMG45689.1 - 5.4e-42 142.0 225.5 2.7e-08 34.2 10.2 12.6 12 0 0 12 12 12 11 Candida agglutinin-like (ALS) DUF3104 PF11302.8 EMG45689.1 - 0.0025 17.5 0.0 61 3.4 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3104) DSPc PF00782.20 EMG45690.1 - 8.3e-07 28.9 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMG45690.1 - 5.8e-05 22.8 0.0 0.00013 21.6 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EMG45690.1 - 0.0059 16.6 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPn PF14671.6 EMG45690.1 - 0.044 14.2 0.0 0.09 13.2 0.0 1.5 1 1 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 EMG45690.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF3402 PF11882.8 EMG45691.1 - 1.6e-95 320.9 31.9 9.9e-95 318.3 24.2 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EMG45691.1 - 5.5e-51 173.5 6.5 2e-50 171.6 6.5 2.0 1 1 0 1 1 1 1 N1221-like protein TAP42 PF04177.12 EMG45691.1 - 0.0039 16.4 0.2 0.0039 16.4 0.2 1.9 2 0 0 2 2 2 1 TAP42-like family CDP-OH_P_transf PF01066.21 EMG45692.1 - 7.6e-17 61.9 0.1 7.6e-17 61.9 0.1 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF378 PF04070.12 EMG45692.1 - 0.66 9.9 7.7 6.3 6.8 7.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF378) Tom22 PF04281.13 EMG45693.1 - 2.3e-47 160.2 0.6 2.6e-47 160.1 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 GvpG PF05120.12 EMG45693.1 - 0.043 13.8 3.5 0.078 13.0 3.5 1.4 1 0 0 1 1 1 0 Gas vesicle protein G DUF1691 PF07950.11 EMG45694.1 - 7.9e-24 84.4 0.3 3.2e-15 56.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 EMG45694.1 - 0.0053 16.8 1.2 0.059 13.4 0.3 2.3 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Tmemb_18A PF09771.9 EMG45695.1 - 0.14 12.5 2.1 9.6 6.6 0.0 2.1 1 1 1 2 2 2 0 Transmembrane protein 188 XPA_C PF05181.12 EMG45696.1 - 1.2e-20 73.2 0.2 2.6e-20 72.1 0.2 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 EMG45696.1 - 0.00017 21.5 2.3 0.00017 21.5 2.3 2.1 2 0 0 2 2 2 1 XPA protein N-terminal Zn_Tnp_IS91 PF14319.6 EMG45696.1 - 6.5 6.9 7.6 0.18 11.8 0.5 2.1 3 0 0 3 3 3 0 Transposase zinc-binding domain HSP90 PF00183.18 EMG45697.1 - 1.6e-222 740.1 33.1 2.6e-222 739.3 33.1 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EMG45697.1 - 1.7e-15 57.5 0.1 3.6e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMG45697.1 - 3.2e-10 40.0 0.0 1.1e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase V-SNARE_C PF12352.8 EMG45698.1 - 5.7e-11 42.5 2.4 5.7e-11 42.5 2.4 2.4 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus SWIRM-assoc_1 PF16495.5 EMG45698.1 - 4.2 7.4 11.5 0.77 9.8 0.1 3.3 2 1 1 3 3 3 0 SWIRM-associated region 1 FAT PF02259.23 EMG45699.1 - 8.7e-77 258.7 5.9 8.7e-77 258.7 5.9 2.8 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 EMG45699.1 - 1.9e-36 126.2 0.1 6.2e-36 124.5 0.1 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EMG45699.1 - 2.4e-06 27.3 0.1 6.2e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 FATC domain BUD22 PF09073.10 EMG45699.1 - 0.0011 18.4 3.7 0.0011 18.4 3.7 3.6 4 0 0 4 4 4 1 BUD22 DUF3385 PF11865.8 EMG45699.1 - 0.0054 16.6 0.6 0.07 13.0 0.1 3.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) TatC PF00902.18 EMG45700.1 - 0.0039 17.1 2.3 0.0051 16.7 2.3 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) UNC45-central PF11701.8 EMG45700.1 - 0.035 14.1 0.7 0.057 13.4 0.7 1.4 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central DUF4064 PF13273.6 EMG45700.1 - 0.036 14.3 1.3 0.061 13.6 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) HemY_N PF07219.13 EMG45700.1 - 0.21 11.8 0.2 0.21 11.8 0.2 1.7 2 0 0 2 2 2 0 HemY protein N-terminus DUF3139 PF11337.8 EMG45700.1 - 0.22 12.2 2.3 0.24 12.1 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) DUF1700 PF08006.11 EMG45700.1 - 0.95 9.0 6.1 2.1 7.8 5.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) PGP_phosphatase PF09419.10 EMG45701.1 - 2.6e-64 215.9 0.0 3.1e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EMG45701.1 - 8.7e-06 25.7 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EMG45701.1 - 0.031 14.3 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 EMG45702.1 - 2.9e-07 30.2 8.6 2.9e-07 30.2 8.6 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMG45702.1 - 0.00068 19.4 9.8 0.00068 19.4 9.8 3.3 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMG45702.1 - 0.0021 17.9 9.7 0.0021 17.9 9.7 3.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 EMG45702.1 - 0.0038 17.9 1.3 0.098 13.5 0.2 7.6 7 1 0 7 7 7 2 C2H2-type zinc finger zf-RING_5 PF14634.6 EMG45702.1 - 0.0052 16.7 10.5 0.0052 16.7 10.5 4.4 4 1 0 4 4 4 1 zinc-RING finger domain zf-C2H2 PF00096.26 EMG45702.1 - 0.011 16.1 1.5 0.049 14.1 0.3 7.4 6 2 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EMG45702.1 - 0.012 15.8 1.3 6.7 7.1 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon Prok-RING_4 PF14447.6 EMG45702.1 - 0.017 15.0 7.5 0.017 15.0 7.5 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2_6 PF13912.6 EMG45702.1 - 0.029 14.4 0.1 0.029 14.4 0.1 4.6 5 1 1 6 6 6 0 C2H2-type zinc finger zf-RING_2 PF13639.6 EMG45702.1 - 2.3 8.6 22.4 0.033 14.5 9.8 3.7 4 0 0 4 4 4 0 Ring finger domain Acyltransferase PF01553.21 EMG45703.1 - 9.1e-21 73.9 0.0 1.7e-20 73.0 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EMG45703.1 - 1.7e-07 31.2 0.3 4.2e-06 26.8 0.4 2.7 2 1 0 2 2 2 1 Acyltransferase C-terminus Fig1 PF12351.8 EMG45704.1 - 3.6e-41 141.2 9.8 3.6e-41 141.2 9.8 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EMG45704.1 - 0.002 17.8 20.3 0.0034 17.1 20.3 1.4 1 1 0 1 1 1 1 SUR7/PalI family zf-SNAP50_C PF12251.8 EMG45704.1 - 0.017 14.8 0.5 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal WD40 PF00400.32 EMG45706.1 - 6e-14 52.2 10.0 0.0095 16.8 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG45706.1 - 8.2e-10 38.9 6.0 0.00046 20.4 0.4 6.3 2 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EMG45706.1 - 1.4e-07 31.2 0.5 2.8e-07 30.3 0.5 1.5 1 0 0 1 1 1 1 LisH PD40 PF07676.12 EMG45706.1 - 0.00057 19.8 1.0 10 6.2 0.0 4.0 3 1 0 3 3 3 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EMG45706.1 - 0.0014 18.5 4.5 0.23 11.3 0.1 4.3 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A DpaA_N PF16924.5 EMG45706.1 - 0.024 14.7 0.0 3.3 7.8 0.0 3.1 3 0 0 3 3 3 0 Dipicolinate synthase subunit A N-terminal domain Nbas_N PF15492.6 EMG45706.1 - 0.032 13.5 0.1 1.6 8.0 0.0 3.1 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 EMG45706.1 - 0.036 13.8 0.4 17 5.2 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Exo84_C PF16528.5 EMG45707.1 - 1.5e-18 67.4 2.6 1.5e-18 67.4 2.6 2.6 2 1 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EMG45707.1 - 0.0083 16.2 4.7 0.0083 16.2 4.7 2.6 2 0 0 2 2 2 1 Vps51/Vps67 Fzo_mitofusin PF04799.13 EMG45707.1 - 0.16 11.5 5.7 0.086 12.4 1.6 2.3 2 0 0 2 2 2 0 fzo-like conserved region COG2 PF06148.11 EMG45707.1 - 0.22 11.6 6.3 0.042 13.9 1.4 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MogR_DNAbind PF12181.8 EMG45707.1 - 0.43 10.5 10.9 0.088 12.7 1.6 3.2 2 1 1 3 3 3 0 DNA binding domain of the motility gene repressor (MogR) DUF1492 PF07374.11 EMG45707.1 - 1.3 9.2 5.4 0.51 10.5 1.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1492) CorA PF01544.18 EMG45707.1 - 3.5 6.9 14.2 1.3 8.3 2.0 2.8 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 EMG45708.1 - 1.5e-42 145.8 23.7 1.5e-42 145.8 23.7 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 EMG45709.1 - 8.6e-60 202.5 0.0 1.2e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMG45709.1 - 6.1e-07 30.3 0.2 1.2e-06 29.4 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YejG PF13989.6 EMG45709.1 - 0.19 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 YejG-like protein Ribosomal_S13_N PF08069.12 EMG45710.1 - 5.1e-30 103.3 0.2 9.2e-30 102.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EMG45710.1 - 2.8e-15 56.3 0.2 4.3e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Tfb4 PF03850.14 EMG45711.1 - 2.9e-99 332.0 2.6 3.6e-99 331.7 2.6 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF4776 PF16003.5 EMG45711.1 - 0.026 13.5 1.2 0.026 13.5 1.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) Porin_OmpL1 PF11389.8 EMG45711.1 - 0.056 12.7 1.7 0.098 11.9 1.7 1.5 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 Rad50_zn_hook PF04423.14 EMG45711.1 - 0.1 12.5 2.4 0.34 10.8 0.3 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif dCMP_cyt_deam_1 PF00383.23 EMG45712.1 - 9.1e-23 80.1 0.0 1.2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMG45712.1 - 1.8e-18 66.6 0.0 2.4e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EMG45712.1 - 0.002 18.2 0.1 0.067 13.3 0.2 2.1 1 1 1 2 2 2 1 Bd3614-like deaminase SNAD4 PF18750.1 EMG45712.1 - 0.0028 17.8 0.0 0.01 16.0 0.0 1.8 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 EMG45712.1 - 0.0036 17.2 0.0 0.058 13.3 0.0 2.0 1 1 0 1 1 1 1 APOBEC-like N-terminal domain NAD2 PF18782.1 EMG45712.1 - 0.0082 16.3 0.0 0.056 13.5 0.0 1.9 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 EMG45712.1 - 0.0083 16.2 0.0 0.048 13.7 0.0 1.9 1 1 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 EMG45712.1 - 0.015 15.4 0.1 0.18 11.9 0.0 2.0 1 1 1 2 2 2 0 Novel AID APOBEC clade 1 Pkinase PF00069.25 EMG45713.1 - 1e-12 48.0 0.0 3.7e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45713.1 - 1.7e-05 24.3 0.0 3.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 EMG45713.1 - 0.0001 23.0 3.4 0.14 13.1 0.1 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat HEAT PF02985.22 EMG45713.1 - 0.00023 21.2 0.6 0.81 10.1 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Kinase-like PF14531.6 EMG45713.1 - 0.0088 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Sensor_TM1 PF13755.6 EMG45713.1 - 0.08 12.7 1.2 11 5.9 0.1 2.6 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain DUF2783 PF10932.8 EMG45713.1 - 0.11 12.1 0.2 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2783) SIP1 PF04938.12 EMG45714.1 - 2.3e-22 79.8 0.1 3e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Baculo_VP91_N PF08475.10 EMG45714.1 - 0.00029 20.6 0.4 0.001 18.8 0.1 1.8 1 1 1 2 2 2 1 Viral capsid protein 91 N-terminal LRR19-TM PF15176.6 EMG45715.1 - 0.0088 16.0 0.1 0.034 14.1 0.0 2.0 2 0 0 2 2 2 1 Leucine-rich repeat family 19 TM domain COX15-CtaA PF02628.15 EMG45716.1 - 2.8e-115 384.9 6.3 3.3e-115 384.6 6.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF3624 PF12292.8 EMG45716.1 - 1.5 9.3 5.5 0.55 10.7 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3624) DUF747 PF05346.11 EMG45717.1 - 1.5e-95 320.4 10.8 2.6e-95 319.6 10.8 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Herpes_capsid PF06112.11 EMG45717.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RPAP2_Rtr1 PF04181.13 EMG45718.1 - 7.2e-23 80.7 1.5 1.2e-22 80.0 1.5 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Complex1_LYR PF05347.15 EMG45719.1 - 4.5e-05 23.4 0.8 0.0022 18.0 0.1 3.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF4337 PF14235.6 EMG45719.1 - 0.012 15.7 2.6 0.028 14.5 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ParB PF08775.10 EMG45719.1 - 0.046 14.2 4.7 0.74 10.3 0.1 3.4 2 1 1 3 3 3 0 ParB family T4_Rnl2_C PF18043.1 EMG45719.1 - 0.5 10.6 6.0 0.14 12.3 1.2 2.6 3 0 0 3 3 3 0 T4 RNA ligase 2 C-terminal SDA1 PF05285.12 EMG45720.1 - 0.019 14.4 25.2 0.026 14.0 25.2 1.1 1 0 0 1 1 1 0 SDA1 DUF3439 PF11921.8 EMG45720.1 - 0.023 14.7 0.3 0.035 14.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mak16 PF04874.14 EMG45720.1 - 0.07 13.7 1.3 0.07 13.7 1.3 2.3 2 0 0 2 2 2 0 Mak16 protein C-terminal region DUF4045 PF13254.6 EMG45720.1 - 0.12 12.0 10.4 0.14 11.8 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BUD22 PF09073.10 EMG45720.1 - 0.17 11.2 20.5 0.21 10.9 20.5 1.1 1 0 0 1 1 1 0 BUD22 Ig_mannosidase PF17753.1 EMG45720.1 - 0.21 11.4 1.2 0.77 9.5 0.0 2.3 2 1 0 2 2 2 0 Ig-fold domain Nop14 PF04147.12 EMG45720.1 - 0.23 9.6 22.3 0.28 9.4 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 EMG45720.1 - 0.33 11.1 21.3 0.43 10.6 21.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 EMG45720.1 - 0.45 8.8 13.9 0.55 8.5 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 EMG45720.1 - 1.6 8.1 16.3 2.2 7.6 16.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Hid1 PF12722.7 EMG45720.1 - 2.7 6.0 8.8 2.9 5.9 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 EMG45720.1 - 3.1 6.7 8.4 3.5 6.5 8.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 EMG45720.1 - 4.3 6.1 6.9 5.4 5.7 6.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PA26 PF04636.13 EMG45720.1 - 4.5 6.1 5.9 5.4 5.8 5.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DNA_pol_phi PF04931.13 EMG45720.1 - 5.5 5.0 21.8 7 4.6 21.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi SURF2 PF05477.11 EMG45720.1 - 7 6.3 15.6 10 5.7 15.6 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Sec62 PF03839.16 EMG45720.1 - 7.8 5.9 10.2 11 5.4 10.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 EMG45720.1 - 9.7 4.8 9.8 10 4.7 9.8 1.1 1 0 0 1 1 1 0 Presenilin DSPn PF14671.6 EMG45721.1 - 1.7e-44 151.7 0.1 1.2e-43 148.9 0.0 2.1 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EMG45721.1 - 2.1e-22 79.4 0.0 2.1e-21 76.1 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMG45721.1 - 3.2e-05 23.6 0.0 5.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EMG45721.1 - 0.1 12.7 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate UPF0561 PF10573.9 EMG45721.1 - 0.11 12.6 0.8 0.32 11.1 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 CDKN3 PF05706.12 EMG45721.1 - 0.12 12.0 0.3 0.24 11.1 0.3 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) MAP65_ASE1 PF03999.12 EMG45721.1 - 5.4 5.6 8.0 7.9 5.0 8.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Cofilin_ADF PF00241.20 EMG45722.1 - 1.6e-22 79.5 0.2 2e-22 79.3 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ctr PF04145.15 EMG45723.1 - 9.4e-26 91.2 1.1 9.7e-26 91.2 0.1 1.5 2 0 0 2 2 2 1 Ctr copper transporter family Perilipin PF03036.16 EMG45723.1 - 4.3 6.3 9.3 6.6 5.6 9.3 1.2 1 0 0 1 1 1 0 Perilipin family Sec8_exocyst PF04048.14 EMG45724.1 - 3.2e-47 160.0 1.1 3.3e-46 156.7 1.1 2.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2451 PF10474.9 EMG45724.1 - 0.0034 17.2 2.8 0.0088 15.9 1.1 2.5 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) ERCC4 PF02732.15 EMG45725.1 - 4.9e-13 49.6 0.5 1e-12 48.5 0.1 1.7 2 0 0 2 2 2 1 ERCC4 domain DUF2340 PF10209.9 EMG45725.1 - 0.53 10.7 0.1 0.53 10.7 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2340) Fes1 PF08609.10 EMG45726.1 - 2e-20 73.4 1.0 6.2e-20 71.9 0.5 2.1 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 SIL1 PF16782.5 EMG45726.1 - 0.0013 18.0 0.2 0.0029 16.9 0.2 1.6 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 DUF3388 PF11868.8 EMG45726.1 - 0.0051 16.2 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) DUF4704 PF15787.5 EMG45726.1 - 0.016 14.5 4.0 1.4 8.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4704) HEAT_EZ PF13513.6 EMG45726.1 - 0.17 12.4 0.0 7 7.3 0.0 2.5 1 1 1 2 2 2 0 HEAT-like repeat PGK PF00162.19 EMG45727.1 - 4.5e-151 503.1 0.5 5e-151 502.9 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase zf-Di19 PF05605.12 EMG45728.1 - 0.037 14.3 0.1 0.13 12.6 0.1 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EMG45728.1 - 6.2 7.9 9.6 1e+02 4.2 0.0 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger Ctr PF04145.15 EMG45729.1 - 7.9e-26 91.5 0.0 1.4e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q2 PF00420.24 EMG45729.1 - 0.093 12.4 2.3 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Peptidase_M91 PF14891.6 EMG45729.1 - 0.12 12.7 2.1 0.22 11.8 2.1 1.3 1 0 0 1 1 1 0 Effector protein zf-Di19 PF05605.12 EMG45730.1 - 0.028 14.7 0.2 0.028 14.7 0.2 2.7 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EMG45730.1 - 0.028 15.2 11.2 0.82 10.7 0.7 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMG45730.1 - 0.099 13.1 7.5 0.12 12.8 2.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 EMG45730.1 - 0.44 11.1 13.5 15 6.3 1.6 4.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type ANF_receptor PF01094.28 EMG45730.1 - 1.3 8.1 7.4 0.51 9.4 0.3 2.2 2 0 0 2 2 2 0 Receptor family ligand binding region RNF220 PF15926.5 EMG45730.1 - 4.3 6.9 9.1 0.2 11.3 3.3 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 zf-BED PF02892.15 EMG45730.1 - 9.5 6.3 8.3 3.6 7.7 4.1 2.5 1 1 1 2 2 2 0 BED zinc finger AA_permease PF00324.21 EMG45731.1 - 9.1e-119 397.2 52.8 1e-118 397.0 52.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45731.1 - 4.7e-31 108.1 63.5 4.7e-31 108.1 63.5 1.8 1 1 1 2 2 2 1 Amino acid permease MitoNEET_N PF10660.9 EMG45731.1 - 2.7 8.1 6.3 21 5.3 0.2 3.3 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus SUN PF03856.13 EMG45732.1 - 2.4e-93 312.1 15.4 3.6e-93 311.5 15.4 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Sporozoite_P67 PF05642.11 EMG45732.1 - 0.0065 14.6 3.2 0.01 13.9 3.2 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Macoilin PF09726.9 EMG45732.1 - 0.12 10.9 0.1 0.15 10.6 0.1 1.0 1 0 0 1 1 1 0 Macoilin family Utp12 PF04003.12 EMG45733.1 - 0.083 13.2 0.1 0.1 12.9 0.1 1.1 1 0 0 1 1 1 0 Dip2/Utp12 Family GSHPx PF00255.19 EMG45734.1 - 3.5e-42 142.4 1.0 5.7e-42 141.7 0.2 1.7 2 0 0 2 2 2 1 Glutathione peroxidase AhpC-TSA PF00578.21 EMG45734.1 - 5.4e-05 23.1 0.0 0.00016 21.5 0.0 1.8 1 1 1 2 2 2 1 AhpC/TSA family PRCC PF10253.9 EMG45735.1 - 0.26 12.0 10.1 0.67 10.7 10.1 1.8 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting V-SNARE_C PF12352.8 EMG45736.1 - 0.33 11.3 5.8 0.4 11.0 1.0 3.2 3 1 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus LPP PF04728.13 EMG45736.1 - 0.53 10.7 8.9 0.53 10.7 3.7 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ChaC PF04752.12 EMG45736.1 - 2.4 8.2 7.2 19 5.2 3.0 2.4 2 0 0 2 2 2 0 ChaC-like protein FA_desaturase PF00487.24 EMG45737.1 - 9.8e-23 81.3 17.7 1.6e-22 80.6 17.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EMG45737.1 - 8.3e-06 26.0 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TMEM213 PF15192.6 EMG45737.1 - 0.04 13.9 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 TMEM213 family Med18 PF09637.10 EMG45738.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Med18 protein P21-Arc PF04062.14 EMG45739.1 - 3.1e-76 255.3 0.0 3.4e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit WD40 PF00400.32 EMG45740.1 - 3.7e-14 52.9 9.5 0.0016 19.2 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG45740.1 - 7.3e-13 48.6 3.1 3.5e-06 27.2 0.3 3.7 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMG45740.1 - 2.8e-06 26.5 0.0 0.014 14.4 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein GSHPx PF00255.19 EMG45741.1 - 1.1e-38 131.1 0.3 1.7e-38 130.5 0.3 1.3 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 EMG45742.1 - 5.8e-46 154.5 0.2 7.6e-46 154.2 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EMG45742.1 - 4.2e-05 23.5 0.1 0.00029 20.8 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMG45742.1 - 0.00081 19.1 0.1 0.0056 16.4 0.1 2.0 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.6 EMG45742.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Inositol_P PF00459.25 EMG45743.1 - 1.8e-53 181.8 1.0 1.4e-52 178.9 1.4 2.1 2 1 0 2 2 2 1 Inositol monophosphatase family Lipase_3 PF01764.25 EMG45743.1 - 1.2e-26 93.3 0.0 2.6e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 EMG45743.1 - 0.00019 21.6 0.1 0.025 14.7 0.0 2.2 2 0 0 2 2 2 2 Thioesterase domain Hydrolase_4 PF12146.8 EMG45743.1 - 0.065 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HA2 PF04408.23 EMG45744.1 - 1.7e-18 66.9 0.0 1.7e-18 66.9 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMG45744.1 - 4.6e-15 55.9 0.0 7.2e-14 52.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMG45744.1 - 2.4e-09 37.4 0.1 1.1e-08 35.3 0.0 2.2 3 0 0 3 3 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EMG45744.1 - 3.1e-07 30.3 0.3 7.9e-07 29.0 0.3 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMG45744.1 - 8.6e-07 29.3 0.1 1.9e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMG45744.1 - 0.0083 15.9 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMG45744.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EMG45744.1 - 0.012 15.3 0.0 0.039 13.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EMG45744.1 - 0.033 14.5 0.1 0.067 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMG45744.1 - 0.057 13.9 0.2 0.057 13.9 0.2 2.7 1 1 1 2 2 1 0 ABC transporter AAA_24 PF13479.6 EMG45744.1 - 0.062 13.0 0.8 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EMG45744.1 - 0.072 12.5 0.0 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein TFIIF_alpha PF05793.12 EMG45744.1 - 0.5 8.9 29.4 0.68 8.5 29.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) tRNA-synt_1b PF00579.25 EMG45745.1 - 1.2e-71 241.4 0.0 1.8e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EMG45745.1 - 0.00013 21.8 0.1 0.00056 19.7 0.1 2.0 1 1 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain AA_permease PF00324.21 EMG45746.1 - 1.7e-89 300.6 33.9 2.1e-89 300.3 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45746.1 - 4.4e-23 81.8 35.6 4.4e-23 81.8 35.6 1.4 1 1 1 2 2 2 1 Amino acid permease DUF1056 PF06341.11 EMG45746.1 - 5.8 7.3 14.3 0.21 11.9 6.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) SH3BGR PF04908.15 EMG45747.1 - 2.4e-05 24.4 0.0 2.4e-05 24.4 0.0 3.5 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 EMG45747.1 - 0.08 13.2 0.0 0.31 11.3 0.0 2.1 1 0 0 1 1 1 0 Glutaredoxin MMU163 PF17119.5 EMG45748.1 - 9.6e-20 70.8 0.2 1.4e-19 70.2 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis Sec20 PF03908.13 EMG45748.1 - 0.022 14.6 0.4 0.045 13.7 0.4 1.4 1 0 0 1 1 1 0 Sec20 VASt PF16016.5 EMG45749.1 - 1.2e-35 123.2 0.1 3.4e-35 121.7 0.1 1.9 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EMG45749.1 - 4.1e-26 91.1 0.0 1.1e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 GRAM domain ABC2_membrane_3 PF12698.7 EMG45749.1 - 0.01 15.0 1.2 0.01 15.0 1.2 2.3 3 1 0 3 3 3 0 ABC-2 family transporter protein TMCCDC2 PF15844.5 EMG45749.1 - 0.01 15.8 0.9 0.022 14.7 0.9 1.5 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 Topo_C_assoc PF14370.6 EMG45749.1 - 0.19 11.7 0.9 6.6 6.7 0.0 2.8 2 0 0 2 2 2 0 C-terminal topoisomerase domain Nop14 PF04147.12 EMG45749.1 - 4 5.5 19.5 9.3 4.3 19.5 1.5 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EMG45749.1 - 9 4.7 11.2 15 4.0 11.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 IlvN PF07991.12 EMG45750.1 - 1.1e-43 148.6 0.0 1.6e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EMG45750.1 - 4.8e-42 143.6 0.0 1e-41 142.6 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 EMG45750.1 - 0.029 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Topoisom_I_N PF02919.15 EMG45751.1 - 3e-99 330.8 0.8 3e-99 330.8 0.8 3.4 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 EMG45751.1 - 1.5e-94 315.6 4.2 1.5e-94 315.6 4.2 2.3 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 EMG45751.1 - 1.5e-32 111.4 0.6 9.8e-32 108.7 0.6 2.6 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4675 PF15720.5 EMG45751.1 - 1.2 8.9 6.1 2.5 7.9 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) Ly49 PF08391.10 EMG45752.1 - 0.00044 20.6 0.3 0.00085 19.7 0.3 1.6 1 1 0 1 1 1 1 Ly49-like protein, N-terminal region Herpes_glycop PF01528.16 EMG45752.1 - 0.0076 15.1 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus glycoprotein M EphA2_TM PF14575.6 EMG45752.1 - 0.075 13.9 0.1 0.19 12.7 0.1 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Sigma_reg_N PF13800.6 EMG45752.1 - 0.19 12.1 0.2 0.19 12.1 0.2 1.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF4834 PF16118.5 EMG45752.1 - 8.9 7.3 6.6 49 5.0 6.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Sec-ASP3 PF15432.6 EMG45753.1 - 0.00098 19.3 0.5 0.0047 17.1 0.0 2.0 2 0 0 2 2 2 1 Accessory Sec secretory system ASP3 DUF4366 PF14283.6 EMG45753.1 - 0.004 17.2 1.5 0.02 15.0 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4366) DUF2076 PF09849.9 EMG45754.1 - 1.3e-07 32.0 11.1 1.6e-07 31.7 11.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EMG45754.1 - 4.2e-05 23.6 4.3 7.2e-05 22.8 4.3 1.4 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EMG45754.1 - 0.0072 16.3 5.3 0.0072 16.3 5.3 1.8 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, YbjQ_1 PF01906.17 EMG45754.1 - 0.13 13.0 0.2 0.19 12.4 0.2 1.2 1 0 0 1 1 1 0 Putative heavy-metal-binding Paramyxo_P_V_N PF13825.6 EMG45754.1 - 0.26 10.7 4.3 0.3 10.5 4.3 1.1 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus AIM5 PF17050.5 EMG45754.1 - 0.29 12.0 2.9 3.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 AflR PF08493.10 EMG45754.1 - 0.34 10.3 7.1 0.48 9.8 7.1 1.3 1 1 0 1 1 1 0 Aflatoxin regulatory protein CYSTM PF12734.7 EMG45754.1 - 3.6 8.0 15.5 8 6.9 4.4 2.7 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Nucleoporin_FG PF13634.6 EMG45754.1 - 8.1 7.4 13.9 21 6.1 13.9 1.7 1 1 0 1 1 1 0 Nucleoporin FG repeat region AA_permease PF00324.21 EMG45755.1 - 3.8e-16 58.7 9.9 4.3e-16 58.6 9.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45755.1 - 0.0038 16.1 6.1 0.0044 15.9 6.1 1.0 1 0 0 1 1 1 1 Amino acid permease Tht1 PF04163.12 EMG45756.1 - 7.6e-21 74.5 8.7 7.6e-21 74.5 8.7 2.7 1 1 1 2 2 2 1 Tht1-like nuclear fusion protein CdiI_2 PF18593.1 EMG45756.1 - 0.029 15.0 0.5 0.39 11.4 0.0 2.7 2 1 1 3 3 3 0 CdiI immunity protein YtxH PF12732.7 EMG45756.1 - 0.73 10.4 3.5 14 6.3 0.1 3.5 3 1 0 3 3 3 0 YtxH-like protein Taxilin PF09728.9 EMG45756.1 - 1.4 8.0 15.6 2.8 7.0 15.6 1.4 1 1 0 1 1 1 0 Myosin-like coiled-coil protein AA_permease PF00324.21 EMG45757.1 - 2.6e-73 247.3 20.9 3.2e-73 247.0 20.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45757.1 - 1.2e-16 60.6 28.1 1.2e-16 60.6 28.1 1.9 1 1 1 2 2 2 1 Amino acid permease Rad52_Rad22 PF04098.15 EMG45758.1 - 9.2e-59 197.8 1.1 1.2e-58 197.4 0.0 1.7 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein GCK PF07802.11 EMG45758.1 - 0.56 10.7 3.1 1.1 9.7 3.1 1.4 1 0 0 1 1 1 0 GCK domain Cmc1 PF08583.10 EMG45758.1 - 8.1 6.5 9.0 15 5.7 8.4 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like ThiF PF00899.21 EMG45759.1 - 2.8e-63 213.5 0.0 4.1e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EMG45759.1 - 1.9e-26 92.0 0.6 3e-26 91.4 0.6 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EMG45759.1 - 0.00014 22.0 0.1 0.00046 20.3 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 EMG45759.1 - 0.0098 16.5 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Ecm33 PF12454.8 EMG45759.1 - 0.057 13.6 0.5 0.1 12.8 0.5 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein PglD_N PF17836.1 EMG45759.1 - 0.067 13.8 0.7 0.31 11.7 0.4 2.4 2 1 0 2 2 2 0 PglD N-terminal domain Abhydrolase_1 PF00561.20 EMG45760.1 - 9.9e-15 54.9 0.0 1.5e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMG45760.1 - 5e-11 43.6 0.0 6.5e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMG45760.1 - 1.1e-10 41.3 0.0 1.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EMG45760.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase LIDHydrolase PF10230.9 EMG45760.1 - 0.058 12.9 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF3530 PF12048.8 EMG45760.1 - 0.096 12.1 0.0 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) SUR7 PF06687.12 EMG45761.1 - 5.1e-40 137.4 3.0 6.9e-40 136.9 3.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Phage_holin_3_6 PF07332.11 EMG45761.1 - 0.0027 17.7 2.0 0.055 13.5 0.1 2.3 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III DUF3742 PF12553.8 EMG45761.1 - 0.063 13.4 0.9 0.21 11.7 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) FAM176 PF14851.6 EMG45761.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 FAM176 family Tmemb_9 PF05434.11 EMG45761.1 - 0.15 12.0 0.7 0.37 10.7 0.1 2.0 2 0 0 2 2 2 0 TMEM9 DUF4044 PF13253.6 EMG45761.1 - 1.5 8.4 3.9 3.5 7.2 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) AEP1 PF17049.5 EMG45762.1 - 7.5e-05 22.0 2.4 7.5e-05 22.0 2.4 2.2 2 1 1 3 3 3 1 ATPase expression protein 1 Na_H_Exchanger PF00999.21 EMG45763.1 - 3.9e-72 243.2 35.5 4.9e-72 242.8 35.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ndc1_Nup PF09531.10 EMG45764.1 - 6.1e-82 276.2 1.2 6.9e-82 276.1 1.2 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup SPT16 PF08644.11 EMG45764.1 - 0.15 12.3 1.2 2.6 8.2 0.1 2.3 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF1132 PF06575.12 EMG45764.1 - 0.16 12.4 1.8 17 5.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1132) LMBR1 PF04791.16 EMG45765.1 - 0.14 11.0 5.5 0.17 10.7 5.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2175 PF09943.9 EMG45765.1 - 0.25 11.7 3.4 0.57 10.5 2.8 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) ERCC4 PF02732.15 EMG45766.1 - 3.3e-24 85.9 0.6 9.2e-24 84.4 0.6 1.7 1 0 0 1 1 1 1 ERCC4 domain DUF4364 PF14277.6 EMG45766.1 - 0.018 14.8 0.6 0.15 11.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4364) HTH_45 PF14947.6 EMG45766.1 - 0.034 14.1 0.2 0.5 10.4 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix HHH_3 PF12836.7 EMG45766.1 - 0.058 13.6 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EMG45766.1 - 1.1 9.9 3.0 1.5 9.5 0.1 2.7 4 0 0 4 4 4 0 Helix-hairpin-helix domain Oxidored_FMN PF00724.20 EMG45769.1 - 8.5e-96 321.2 0.0 9.8e-96 321.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Mito_carr PF00153.27 EMG45770.1 - 7.9e-31 105.8 4.1 3.8e-15 55.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.16 EMG45771.1 - 1e-43 149.8 25.7 1.4e-43 149.4 25.7 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EMG45771.1 - 7.9e-07 29.3 32.1 0.00026 21.2 13.3 3.1 2 2 0 2 2 2 2 EamA-like transporter family Cu-oxidase_3 PF07732.15 EMG45772.1 - 8.4e-38 129.0 0.3 1.1e-37 128.7 0.3 1.1 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 EMG45772.1 - 0.0001 22.4 0.0 0.00013 22.1 0.0 1.2 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMG45772.1 - 0.0019 18.0 0.2 0.0078 16.0 0.2 1.8 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMG45773.1 - 7.3e-49 165.0 5.9 7.2e-43 145.6 0.8 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMG45773.1 - 8.6e-45 151.6 1.5 1.3e-41 141.3 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EMG45773.1 - 1.9e-37 128.8 2.3 6.6e-31 107.6 1.3 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EMG45773.1 - 0.043 13.9 0.0 9.5 6.4 0.0 3.3 3 0 0 3 3 3 0 Cupredoxin-like domain Fanconi_A PF03511.14 EMG45773.1 - 0.16 11.9 0.3 0.47 10.4 0.3 1.8 1 0 0 1 1 1 0 Fanconi anaemia group A protein DUF4894 PF16235.5 EMG45774.1 - 0.14 12.5 3.4 0.52 10.7 0.2 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4894) EzrA PF06160.12 EMG45774.1 - 0.3 9.2 35.8 0.46 8.6 35.8 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA PilO PF04350.13 EMG45774.1 - 1 9.5 14.4 1.2 9.3 0.9 3.6 2 1 0 3 3 3 0 Pilus assembly protein, PilO Cytochrom_B562 PF07361.11 EMG45774.1 - 2.4 8.9 20.2 0.37 11.5 5.7 3.6 2 2 2 4 4 4 0 Cytochrome b562 ACCA PF03255.14 EMG45774.1 - 2.8 7.8 20.7 0.085 12.7 0.8 3.9 3 2 1 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit tRNA-synt_2b PF00587.25 EMG45775.1 - 1.8e-25 89.9 0.0 3.1e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EMG45775.1 - 3.6e-06 27.1 5.0 3.6e-06 27.1 5.0 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain End3 PF12761.7 EMG45775.1 - 0.1 12.8 2.6 0.19 11.9 2.6 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Tektin PF03148.14 EMG45775.1 - 0.12 11.1 4.7 0.052 12.3 1.2 2.0 2 1 0 2 2 2 0 Tektin family GAS PF13851.6 EMG45775.1 - 0.25 10.7 6.1 0.091 12.1 1.4 2.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 EMG45775.1 - 3.5 7.6 9.7 0.86 9.6 4.9 2.4 2 1 0 2 2 2 0 Prefoldin subunit XhlA PF10779.9 EMG45775.1 - 6 7.1 6.1 1.6 9.0 1.0 2.4 2 1 1 3 3 2 0 Haemolysin XhlA AA_permease PF00324.21 EMG45776.1 - 6.9e-119 397.6 38.5 7.8e-119 397.4 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45776.1 - 2.4e-33 115.6 41.7 3e-33 115.3 41.7 1.1 1 0 0 1 1 1 1 Amino acid permease GSHPx PF00255.19 EMG45777.1 - 4.5e-38 129.2 0.3 6.4e-38 128.7 0.3 1.2 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 EMG45778.1 - 2.1e-41 139.8 0.4 2.7e-41 139.5 0.4 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EMG45778.1 - 0.036 14.0 0.2 0.32 10.9 0.2 2.1 1 1 0 1 1 1 0 AhpC/TSA family Ribosomal_L1 PF00687.21 EMG45779.1 - 6.7e-46 156.6 7.2 6.7e-46 156.6 7.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF4769 PF15992.5 EMG45779.1 - 0.029 14.2 0.9 0.065 13.0 0.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4769) Cu-oxidase_2 PF07731.14 EMG45780.1 - 1e-47 161.3 3.6 2.8e-42 143.7 0.1 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMG45780.1 - 1.3e-43 147.8 0.7 3.4e-40 136.7 0.1 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EMG45780.1 - 9.9e-38 129.8 2.1 7.9e-33 113.8 1.2 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMG45781.1 - 1.5e-43 147.8 1.5 3.2e-43 146.7 1.5 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 EMG45781.1 - 0.0046 17.1 0.2 0.0046 17.1 0.2 2.7 3 1 0 3 3 3 1 Multicopper oxidase NDC10_II PF16787.5 EMG45782.1 - 1.8e-22 79.8 11.3 1.8e-22 79.8 11.3 2.6 2 1 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Mlp PF03304.13 EMG45782.1 - 0.22 11.7 11.6 0.37 11.0 0.1 3.0 2 1 0 2 2 2 0 Mlp lipoprotein family Lgl_C PF08596.10 EMG45783.1 - 1.3e-127 425.8 0.5 2.2e-127 425.0 0.3 1.5 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 EMG45783.1 - 5.5e-10 39.4 0.3 0.023 15.0 0.0 5.8 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMG45783.1 - 0.0012 19.6 0.1 10 7.2 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EMG45783.1 - 0.0093 14.7 3.5 0.17 10.6 0.0 3.8 3 2 1 4 4 4 1 Nup133 N terminal like DPM2 PF07297.12 EMG45784.1 - 2.1e-32 111.2 0.4 2.6e-32 110.9 0.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Adap_comp_sub PF00928.21 EMG45785.1 - 5.1e-42 144.1 4.8 6.3e-35 120.8 0.5 2.1 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMG45785.1 - 0.00014 21.8 0.1 0.00029 20.8 0.1 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 EMG45785.1 - 0.042 13.9 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain CPSF73-100_C PF11718.8 EMG45785.1 - 0.06 12.9 0.1 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term V_ATPase_I PF01496.19 EMG45786.1 - 1.5e-287 955.9 16.6 1.6e-221 737.6 8.6 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DUF5455 PF17537.2 EMG45786.1 - 0.018 15.5 1.8 0.98 9.9 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5455) Sel1 PF08238.12 EMG45787.1 - 1.1e-22 80.0 14.7 1.2e-06 28.9 0.0 10.0 10 0 0 10 10 10 5 Sel1 repeat TPR_16 PF13432.6 EMG45787.1 - 0.017 15.7 0.9 7 7.4 0.0 4.0 5 1 1 6 6 6 0 Tetratricopeptide repeat Goodbye PF17109.5 EMG45787.1 - 0.022 15.2 0.0 0.064 13.7 0.0 1.8 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Cadherin_C_2 PF16492.5 EMG45787.1 - 0.038 14.7 0.0 0.12 13.1 0.0 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal TPR_14 PF13428.6 EMG45787.1 - 0.043 14.6 0.0 35 5.6 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMG45787.1 - 0.1 12.3 8.0 1 9.1 0.5 4.9 6 0 0 6 6 6 0 TPR repeat TPR_1 PF00515.28 EMG45787.1 - 0.27 11.1 10.8 3.9 7.5 0.0 6.2 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMG45787.1 - 1.7 8.9 13.5 2.9 8.2 0.0 6.8 8 2 0 8 8 8 0 Tetratricopeptide repeat Dna2 PF08696.11 EMG45788.1 - 1.1e-56 191.9 2.1 2.1e-56 191.0 0.1 2.5 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_11 PF13086.6 EMG45788.1 - 2.3e-30 106.3 16.6 1.9e-16 60.7 0.0 4.0 2 2 1 3 3 2 2 AAA domain AAA_12 PF13087.6 EMG45788.1 - 3.9e-25 88.7 0.0 3.9e-25 88.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMG45788.1 - 4.8e-13 49.3 0.0 9.8e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMG45788.1 - 5e-12 46.4 0.0 1.4e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 EMG45788.1 - 1.5e-06 28.4 0.2 4e-06 27.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF83 Helicase_RecD PF05127.14 EMG45788.1 - 2.3e-05 24.3 0.0 6.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Helicase PDDEXK_1 PF12705.7 EMG45788.1 - 3.2e-05 24.0 0.1 6.9e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UvrD-helicase PF00580.21 EMG45788.1 - 0.0003 20.4 0.0 0.0003 20.4 0.0 3.3 3 1 0 3 3 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 EMG45788.1 - 0.0004 19.7 0.3 0.09 11.9 0.1 2.5 2 0 0 2 2 2 1 PIF1-like helicase Viral_helicase1 PF01443.18 EMG45788.1 - 0.00085 19.1 2.2 0.23 11.2 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 EMG45788.1 - 0.0016 18.1 0.2 0.0048 16.6 0.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 EMG45788.1 - 0.017 14.6 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EMG45788.1 - 0.02 14.2 0.0 0.062 12.6 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 EMG45788.1 - 0.029 14.7 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EMG45788.1 - 0.061 13.2 0.2 0.18 11.7 0.2 1.8 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 EMG45788.1 - 0.08 13.5 0.2 0.51 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EMG45788.1 - 0.097 13.1 0.7 0.36 11.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EMG45788.1 - 0.11 12.1 0.6 0.46 10.0 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EMG45788.1 - 0.13 12.5 0.0 0.39 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Nop PF01798.18 EMG45789.1 - 1.5e-83 279.8 0.2 1.5e-83 279.8 0.2 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EMG45789.1 - 2.2e-20 72.8 2.4 2.2e-20 72.8 2.4 2.7 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DUF4604 PF15377.6 EMG45789.1 - 9 6.7 50.4 0.24 11.8 43.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) TPR_1 PF00515.28 EMG45790.1 - 2.9e-12 45.9 0.0 0.0014 18.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMG45790.1 - 4.1e-10 39.0 0.0 0.015 15.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMG45790.1 - 2.3e-05 24.3 0.2 0.16 12.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMG45790.1 - 3.5e-05 23.4 0.4 0.014 15.1 0.1 3.4 1 1 2 3 3 3 1 TPR repeat TPR_12 PF13424.6 EMG45790.1 - 0.0014 18.9 0.0 1.8 8.9 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 EMG45790.1 - 0.023 14.2 0.0 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 SHNi-TPR EcoEI_R_C PF08463.10 EMG45790.1 - 0.047 13.8 0.5 10 6.2 0.0 3.6 3 1 1 4 4 4 0 EcoEI R protein C-terminal TPR_9 PF13371.6 EMG45790.1 - 0.13 12.4 0.0 0.78 9.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 EMG45791.1 - 3.3e-65 220.1 0.0 6.5e-65 219.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45791.1 - 1.6e-32 112.8 0.5 7.4e-31 107.4 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMG45791.1 - 4.1e-06 26.0 1.1 4.1e-06 26.0 1.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EMG45791.1 - 1e-05 25.0 0.0 0.0014 18.1 0.0 2.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EMG45791.1 - 0.043 13.2 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMG45791.1 - 0.19 10.5 0.0 0.19 10.5 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Peptidase_M3 PF01432.20 EMG45792.1 - 2.4e-106 356.7 0.1 3.2e-106 356.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EMG45792.1 - 0.23 11.1 0.2 0.36 10.4 0.2 1.2 1 0 0 1 1 1 0 Peptidase M50B-like AA_permease PF00324.21 EMG45793.1 - 6.9e-123 410.7 34.6 7.9e-123 410.6 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG45793.1 - 2e-33 115.9 37.1 2.4e-33 115.6 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 EMG45793.1 - 0.15 10.8 1.2 0.27 10.0 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) HLH PF00010.26 EMG45795.1 - 1.1e-16 60.6 0.1 1.1e-16 60.6 0.1 2.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain VasI PF11319.8 EMG45795.1 - 0.035 13.8 0.9 0.1 12.2 0.9 1.8 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 PAC1 PF16094.5 EMG45795.1 - 0.2 10.8 3.2 0.45 9.6 3.2 1.5 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 AIM5 PF17050.5 EMG45795.1 - 6.1 7.7 9.3 2.2 9.2 5.1 2.6 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 SWIM PF04434.17 EMG45796.1 - 0.011 15.3 1.0 0.52 10.0 0.1 2.3 2 0 0 2 2 2 0 SWIM zinc finger End_beta_barrel PF12195.8 EMG45796.1 - 0.083 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase PH_18 PF18469.1 EMG45797.1 - 9.2e-50 168.3 0.5 2.1e-49 167.1 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Rtt106 PF08512.12 EMG45797.1 - 1.5e-21 76.6 0.9 1.5e-20 73.4 0.2 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Rtt106_N PF18215.1 EMG45797.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain Aminotran_1_2 PF00155.21 EMG45798.1 - 2.5e-20 73.0 0.0 2.9e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EMG45798.1 - 0.00018 20.4 0.0 0.0031 16.3 0.0 2.5 3 0 0 3 3 3 1 Alanine-glyoxylate amino-transferase PX PF00787.24 EMG45799.1 - 8.7e-15 54.7 0.6 2.8e-14 53.1 0.0 2.1 2 1 1 3 3 3 1 PX domain SNARE PF05739.19 EMG45799.1 - 0.0095 15.9 0.3 0.037 14.0 0.1 2.0 2 0 0 2 2 2 1 SNARE domain CobN-Mg_chel PF02514.16 EMG45799.1 - 1.1 6.9 8.6 1.4 6.5 8.6 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase DUF4407 PF14362.6 EMG45799.1 - 3.8 6.8 7.6 5.7 6.2 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2417 PF10329.9 EMG45800.1 - 2.9e-68 229.8 3.1 4.2e-68 229.3 3.1 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 EMG45800.1 - 8.9e-08 32.1 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EMG45800.1 - 7.1e-06 26.3 0.0 9.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EMG45800.1 - 0.0013 19.3 0.0 0.0022 18.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FHA PF00498.26 EMG45801.1 - 7.6e-13 48.6 0.0 2.1e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EMG45801.1 - 8.4e-11 41.4 2.6 1.7e-10 40.4 2.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EMG45801.1 - 6.1e-08 32.9 7.9 1.1e-07 32.1 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain PIG-S PF10510.9 EMG45801.1 - 2e-07 30.2 9.8 6.3e-05 22.0 0.1 3.2 3 0 0 3 3 3 2 Phosphatidylinositol-glycan biosynthesis class S protein zf-RING_5 PF14634.6 EMG45801.1 - 8.7e-05 22.4 4.7 0.00016 21.6 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMG45801.1 - 0.00014 21.7 7.0 0.00025 20.8 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMG45801.1 - 0.0013 19.0 6.5 0.0037 17.5 6.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain PHD PF00628.29 EMG45801.1 - 0.0015 18.4 4.2 0.0032 17.3 4.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-C3HC4 PF00097.25 EMG45801.1 - 0.0015 18.4 6.1 0.0028 17.5 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG45801.1 - 0.0017 18.3 7.8 0.0034 17.4 7.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EMG45801.1 - 0.0022 18.0 3.9 0.0042 17.1 3.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Yop-YscD_cpl PF16697.5 EMG45801.1 - 0.007 16.7 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Podoplanin PF05808.11 EMG45801.1 - 0.053 13.6 3.5 0.13 12.4 3.5 1.6 1 0 0 1 1 1 0 Podoplanin zf-C3HC4_3 PF13920.6 EMG45801.1 - 0.15 12.0 6.7 0.25 11.2 6.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMG45801.1 - 0.22 11.7 7.1 0.43 10.8 7.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Acetyltransf_1 PF00583.25 EMG45802.1 - 4.9e-14 52.6 0.0 5.8e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMG45802.1 - 2e-07 31.3 0.0 2.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMG45802.1 - 3.1e-05 23.9 0.0 3.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMG45802.1 - 9.8e-05 23.0 0.0 0.00013 22.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMG45802.1 - 0.014 15.6 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AstA PF04958.12 EMG45802.1 - 0.065 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit PanZ PF12568.8 EMG45802.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ adh_short_C2 PF13561.6 EMG45803.1 - 1e-49 169.2 0.1 2.1e-49 168.2 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMG45803.1 - 2e-35 122.0 0.2 4.5e-35 120.9 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG45803.1 - 4.6e-07 29.9 0.0 7.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KR domain UCH PF00443.29 EMG45804.1 - 1.2e-48 165.8 3.6 3.2e-48 164.5 3.6 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMG45804.1 - 7.8e-13 48.7 4.0 7.8e-13 48.7 4.0 3.0 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase EF-G-binding_N PF07299.11 EMG45804.1 - 0.12 12.9 3.6 0.2 12.2 1.2 2.6 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal VID27 PF08553.10 EMG45806.1 - 2.4e-155 517.0 1.0 3.5e-155 516.4 1.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EMG45806.1 - 2.8e-53 180.3 0.6 2.8e-53 180.3 0.6 4.0 4 0 0 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 EMG45806.1 - 1.1e-29 102.9 3.3 2.1e-29 102.0 1.6 2.2 2 0 0 2 2 2 1 VID27 PH-like domain DUF719 PF05334.13 EMG45806.1 - 1.9 8.6 9.1 12 6.0 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF719) RXT2_N PF08595.11 EMG45806.1 - 2 8.5 26.4 3 7.9 9.7 3.4 3 0 0 3 3 3 0 RXT2-like, N-terminal RPA43_OB PF17875.1 EMG45806.1 - 8 7.1 13.8 1.1 9.9 1.5 3.0 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I RNA_pol_Rpc4 PF05132.14 EMG45806.1 - 8.5 6.8 10.6 9.1 6.7 0.5 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF2076 PF09849.9 EMG45807.1 - 0.096 12.7 14.0 0.27 11.2 0.5 3.9 2 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2076) GLTP PF08718.11 EMG45808.1 - 6.9e-48 162.7 0.1 1.1e-47 162.1 0.1 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Hormone_2 PF00123.20 EMG45808.1 - 0.14 12.1 0.2 0.35 10.8 0.2 1.6 1 0 0 1 1 1 0 Peptide hormone DUF3246 PF11596.8 EMG45809.1 - 2.5e-107 357.9 184.5 3.8e-90 301.6 76.2 8.9 3 3 5 8 8 8 6 Protein of unknown function (DUF3246) Frag1 PF10277.9 EMG45810.1 - 2e-55 187.7 21.0 2.4e-55 187.5 21.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF962 PF06127.11 EMG45810.1 - 0.055 13.6 3.4 0.88 9.7 3.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF962) GWT1 PF06423.12 EMG45810.1 - 5.3 7.2 10.4 1.9 8.6 6.5 2.3 2 1 0 2 2 2 0 GWT1 RRM_1 PF00076.22 EMG45811.1 - 4.2e-27 93.8 2.1 1.4e-12 47.2 0.1 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMG45811.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_7 PF16367.5 EMG45811.1 - 0.073 13.2 0.1 2.2 8.5 0.0 3.3 3 1 0 3 3 3 0 RNA recognition motif Pox_P35 PF03213.14 EMG45811.1 - 0.09 12.0 0.4 0.15 11.3 0.4 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein DUF148 PF02520.17 EMG45812.1 - 0.0024 17.9 1.1 7.7 6.7 0.0 3.5 2 2 1 3 3 3 2 Domain of unknown function DUF148 Collagen_mid PF15984.5 EMG45812.1 - 0.0024 17.6 6.7 0.0047 16.7 6.7 1.6 1 0 0 1 1 1 1 Bacterial collagen, middle region Baculo_PEP_C PF04513.12 EMG45812.1 - 0.02 14.9 7.6 0.12 12.4 7.6 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus EAP30 PF04157.16 EMG45812.1 - 0.032 13.5 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family TrbL PF04610.14 EMG45812.1 - 0.097 12.4 2.3 7.1 6.3 0.1 2.9 1 1 2 3 3 3 0 TrbL/VirB6 plasmid conjugal transfer protein Perilipin PF03036.16 EMG45812.1 - 0.29 10.1 1.8 3.9 6.4 1.8 2.2 1 1 0 1 1 1 0 Perilipin family Flo11 PF10182.9 EMG45813.1 - 1.4e-09 38.3 0.0 2.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Flo11 domain Adaptin_N PF01602.20 EMG45814.1 - 1.6e-87 294.2 5.6 2.1e-87 293.9 5.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EMG45814.1 - 3.3e-15 56.5 2.7 5.6e-12 46.0 0.0 4.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMG45814.1 - 7.3e-10 39.1 0.5 2.8e-07 30.8 0.0 4.1 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.22 EMG45814.1 - 0.0022 18.1 0.0 15 6.1 0.0 4.5 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 EMG45814.1 - 0.013 16.0 0.3 7.3 7.2 0.1 4.0 3 1 1 4 4 4 0 HEAT-like repeat XPG_N PF00752.17 EMG45815.1 - 1.3e-35 121.9 0.0 4.5e-35 120.2 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EMG45815.1 - 2.6e-27 95.0 0.5 2.1e-26 92.1 0.1 2.9 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 EMG45815.1 - 0.0037 17.8 0.0 0.0037 17.8 0.0 3.2 3 1 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 EMG45815.1 - 0.0037 17.5 0.0 0.0082 16.4 0.0 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family JmjC PF02373.22 EMG45816.1 - 1.1e-39 135.3 1.8 3.3e-39 133.8 1.8 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EMG45816.1 - 4.5e-15 55.3 1.9 9.7e-15 54.3 1.9 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 EMG45816.1 - 1.8e-13 50.5 9.6 1.8e-13 50.5 9.6 2.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EMG45816.1 - 9.9e-11 41.8 9.1 9.9e-11 41.8 9.1 2.1 2 1 0 2 2 2 1 PHD-zinc-finger like domain Rad17 PF03215.15 EMG45817.1 - 9.1e-13 48.5 0.1 6.9e-12 45.7 0.1 2.2 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EMG45817.1 - 0.0023 18.3 0.0 0.0033 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EMG45817.1 - 0.0034 17.9 0.1 0.0038 17.7 0.1 1.5 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 EMG45817.1 - 0.0045 17.3 0.0 0.0093 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 EMG45817.1 - 0.0084 16.4 0.0 0.035 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMG45817.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EMG45817.1 - 0.022 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EMG45817.1 - 0.055 12.7 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Spike_torovirin PF17072.5 EMG45817.1 - 0.17 9.0 0.0 0.2 8.8 0.0 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein AAA_30 PF13604.6 EMG45817.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Hyphal_reg_CWP PF11765.8 EMG45818.1 - 5.5e-84 281.9 7.1 6.9e-84 281.6 7.1 1.1 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 EMG45818.1 - 6.9e-11 41.5 19.0 3.2e-05 23.4 4.9 3.5 2 1 1 3 3 3 3 Hyphally regulated cell wall GPI-anchored protein 1 DSS1_SEM1 PF05160.13 EMG45819.1 - 2.7e-19 69.0 22.7 3.4e-19 68.6 22.7 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.29 EMG45820.1 - 7.7e-41 139.6 0.0 1.4e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EMG45820.1 - 4.5e-18 65.0 0.0 9.7e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EMG45820.1 - 2.5e-08 33.6 0.0 6.9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EMG45820.1 - 6.3e-05 23.4 2.3 0.021 15.2 0.0 2.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EMG45820.1 - 9.6e-05 22.6 0.0 0.00027 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EMG45820.1 - 0.0007 19.4 0.1 0.0016 18.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EMG45820.1 - 0.0021 18.1 1.6 0.0067 16.4 0.2 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMG45820.1 - 0.0035 17.6 2.0 0.16 12.3 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EMG45820.1 - 0.0048 17.1 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain JIP_LZII PF16471.5 EMG45820.1 - 0.012 15.7 3.4 0.012 15.7 3.4 2.1 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF815 PF05673.13 EMG45820.1 - 0.014 14.6 0.1 0.03 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EMG45820.1 - 0.017 14.5 0.2 0.044 13.1 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EMG45820.1 - 0.018 14.5 0.1 0.065 12.7 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 EMG45820.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein dCMP_cyt_deam_1 PF00383.23 EMG45821.1 - 8.7e-13 48.0 0.0 1.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EMG45821.1 - 1.2e-09 38.5 0.9 1.5e-06 28.4 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EMG45821.1 - 2.7e-05 23.9 0.3 0.0086 15.7 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Ctr PF04145.15 EMG45823.1 - 1.1e-31 110.5 5.1 1.3e-31 110.2 5.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Transp_cyt_pur PF02133.15 EMG45824.1 - 4.1e-45 154.4 25.3 4.9e-45 154.1 25.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GST_N_3 PF13417.6 EMG45825.1 - 9.9e-15 54.7 0.0 1.7e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMG45825.1 - 2.7e-12 46.8 0.0 6.6e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMG45825.1 - 7.4e-11 42.1 0.1 1.3e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMG45825.1 - 3.6e-10 40.0 0.0 7.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMG45825.1 - 2.2e-09 37.4 0.1 4e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMG45825.1 - 1.5e-08 34.5 0.0 2.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SBF PF01758.16 EMG45826.1 - 1.3e-48 165.3 15.1 1.3e-48 165.3 15.1 2.2 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF3464 PF11947.8 EMG45826.1 - 0.15 11.8 2.7 0.15 11.8 0.3 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 UQ_con PF00179.26 EMG45827.1 - 0.01 15.5 0.7 0.21 11.2 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme Prok-E2_E PF14462.6 EMG45827.1 - 0.013 15.3 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family E RTX PF02382.15 EMG45827.1 - 0.017 14.8 0.4 0.46 10.1 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain in RTX protein ABC_membrane_2 PF06472.15 EMG45827.1 - 0.034 13.6 0.1 0.06 12.7 0.1 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 DUF737 PF05300.11 EMG45827.1 - 0.048 14.0 2.8 0.079 13.3 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Adeno_E1A PF02703.14 EMG45827.1 - 0.056 13.0 1.4 0.093 12.3 1.4 1.3 1 0 0 1 1 1 0 Early E1A protein RWD PF05773.22 EMG45827.1 - 1.2 9.5 6.5 1 9.7 2.3 2.7 1 1 1 2 2 2 0 RWD domain PseudoU_synth_2 PF00849.22 EMG45828.1 - 3.2e-15 56.6 0.0 4.2e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF3759 PF12585.8 EMG45829.1 - 2e-31 107.9 2.9 2.3e-31 107.7 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3824 PF12868.7 EMG45829.1 - 0.014 16.1 2.4 0.51 11.0 2.4 2.0 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) AAA-ATPase_like PF09820.9 EMG45829.1 - 0.095 12.1 0.1 0.097 12.1 0.1 1.0 1 0 0 1 1 1 0 Predicted AAA-ATPase DUF2114 PF09887.9 EMG45829.1 - 0.12 10.9 0.0 0.55 8.7 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2114) Zip PF02535.22 EMG45830.1 - 1.1e-41 143.1 27.4 1.5e-38 132.9 27.4 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.12 EMG45830.1 - 0.00052 19.5 12.1 0.0033 16.9 3.8 2.5 2 0 0 2 2 2 2 HupE / UreJ protein HRXXH PF13933.6 EMG45831.1 - 6.3e-104 346.9 2.3 8.1e-104 346.5 2.3 1.1 1 0 0 1 1 1 1 Putative peptidase family HCV_NS5a_1a PF08300.13 EMG45831.1 - 0.064 13.4 0.2 0.15 12.2 0.2 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain CDC45 PF02724.14 EMG45831.1 - 0.21 9.8 10.4 0.29 9.4 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 EMG45831.1 - 0.44 10.3 7.3 0.81 9.4 7.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.13 EMG45831.1 - 1.1 8.2 13.4 1.7 7.5 13.4 1.2 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 EMG45831.1 - 1.1 7.4 15.8 1.4 7.0 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EMG45831.1 - 1.2 8.5 15.0 1.7 8.0 15.0 1.2 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 EMG45831.1 - 3.2 6.2 11.4 4.8 5.6 11.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 EMG45831.1 - 4.1 6.6 16.3 8.2 5.6 16.3 1.5 1 0 0 1 1 1 0 NOA36 protein LicD PF04991.13 EMG45832.1 - 4.2e-26 92.5 4.6 1.4e-21 77.7 0.2 3.0 2 1 1 3 3 3 2 LicD family ABC2_membrane PF01061.24 EMG45833.1 - 2.6e-31 108.7 28.7 4e-31 108.1 28.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EMG45833.1 - 4.5e-26 92.0 0.1 6.8e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMG45833.1 - 1.9e-09 37.3 0.5 1.2e-08 34.7 0.5 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMG45833.1 - 4e-06 26.9 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EMG45833.1 - 5.9e-06 26.3 0.3 0.00011 22.2 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EMG45833.1 - 1.3e-05 24.8 0.2 2.8e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EMG45833.1 - 7.2e-05 23.4 0.2 0.00013 22.6 0.2 1.4 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.7 EMG45833.1 - 0.0022 17.2 26.0 0.0024 17.1 24.9 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_22 PF13401.6 EMG45833.1 - 0.0063 16.8 0.1 0.017 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMG45833.1 - 0.0067 16.0 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EMG45833.1 - 0.0083 16.2 0.1 0.031 14.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 EMG45833.1 - 0.009 16.4 0.2 0.29 11.6 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMG45833.1 - 0.0095 16.3 0.1 0.016 15.6 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EMG45833.1 - 0.013 15.4 0.1 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_15 PF13175.6 EMG45833.1 - 0.018 14.8 0.1 0.25 11.0 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 EMG45833.1 - 0.026 14.8 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain HK PF02110.15 EMG45833.1 - 0.063 12.7 0.1 4 6.7 0.0 2.2 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family AAA_18 PF13238.6 EMG45833.1 - 0.071 13.7 0.2 0.5 10.9 0.1 2.2 2 1 1 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 EMG45833.1 - 0.086 12.6 0.7 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase Dynamin_N PF00350.23 EMG45833.1 - 0.092 12.8 1.4 0.22 11.5 1.4 1.6 1 1 0 1 1 1 0 Dynamin family ABC_ATPase PF09818.9 EMG45833.1 - 0.092 11.5 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 EMG45833.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMG45833.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Aminotran_3 PF00202.21 EMG45834.1 - 7.6e-119 397.0 0.0 8.9e-119 396.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMG45834.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II Metallophos PF00149.28 EMG45836.1 - 5.4e-36 125.0 0.4 1e-35 124.1 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EMG45836.1 - 0.056 13.1 0.1 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain Img2 PF05046.14 EMG45837.1 - 5.5e-19 68.2 1.3 5.7e-19 68.2 0.6 1.4 2 0 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) Pox_Rif PF03340.13 EMG45837.1 - 0.0054 15.2 0.0 0.0055 15.2 0.0 1.0 1 0 0 1 1 1 1 Poxvirus rifampicin resistance protein Pkinase PF00069.25 EMG45838.1 - 3e-66 223.5 0.0 6.9e-66 222.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45838.1 - 9e-38 130.0 0.2 4.3e-26 91.7 0.2 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EMG45838.1 - 0.00042 19.7 0.1 0.0072 15.7 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EMG45838.1 - 0.0062 16.5 0.1 0.031 14.2 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EMG45838.1 - 0.043 13.2 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_knob PF00541.17 EMG45838.1 - 0.045 13.5 0.3 0.12 12.1 0.3 1.7 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) DUF4145 PF13643.6 EMG45838.1 - 0.14 12.3 0.0 0.45 10.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) WD40 PF00400.32 EMG45839.1 - 6.5e-57 188.2 38.4 1.5e-10 41.5 0.0 9.9 9 1 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG45839.1 - 1.6e-17 63.6 5.7 0.0001 22.5 0.0 6.6 3 3 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMG45839.1 - 3.4e-07 29.6 2.4 0.0088 15.0 0.0 4.7 5 1 1 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EMG45839.1 - 3.6e-06 27.0 0.7 0.13 12.2 0.0 4.1 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EMG45839.1 - 2.1e-05 23.4 8.1 1.2 7.7 0.1 5.0 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EMG45839.1 - 0.00048 19.0 0.5 0.00048 19.0 0.5 2.7 3 1 0 3 3 3 1 Nup133 N terminal like WD40_like PF17005.5 EMG45839.1 - 0.0061 15.9 0.0 3.6 6.8 0.0 3.6 4 0 0 4 4 4 1 WD40-like domain Frtz PF11768.8 EMG45839.1 - 0.0089 14.4 0.0 0.86 7.8 0.0 2.8 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 EMG45839.1 - 0.02 14.6 4.3 0.11 12.2 0.5 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split PD40 PF07676.12 EMG45839.1 - 0.05 13.6 0.5 28 4.8 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat LRR_8 PF13855.6 EMG45840.1 - 0.0051 16.6 0.7 0.0051 16.6 0.7 7.2 7 2 1 8 8 8 3 Leucine rich repeat F-box-like PF12937.7 EMG45840.1 - 0.076 12.9 0.4 0.19 11.6 0.4 1.7 1 0 0 1 1 1 0 F-box-like FNIP PF05725.12 EMG45840.1 - 0.29 11.3 28.4 10 6.4 0.1 9.1 9 2 1 10 10 10 0 FNIP Repeat SKG6 PF08693.10 EMG45841.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MFS_1 PF07690.16 EMG45842.1 - 9.6e-31 107.0 36.2 2e-30 105.9 36.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2542 PF10808.8 EMG45842.1 - 0.11 13.0 4.3 0.18 12.3 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) Fmp27_WPPW PF10359.9 EMG45844.1 - 3e-138 461.7 10.1 8.5e-138 460.2 10.1 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.9 EMG45844.1 - 1.8e-133 446.6 55.6 4.2e-133 445.4 55.6 1.7 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 EMG45844.1 - 2e-107 360.0 10.0 2e-107 360.0 10.0 3.4 5 0 0 5 5 5 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 EMG45844.1 - 1.3e-52 178.1 0.0 5.1e-52 176.1 0.0 2.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EMG45844.1 - 5.1e-47 159.6 2.1 5.1e-47 159.6 2.1 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EMG45844.1 - 5.7e-21 75.2 0.2 5.7e-21 75.2 0.2 4.2 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain RabGAP-TBC PF00566.18 EMG45845.1 - 6.9e-51 173.0 0.7 2.5e-50 171.1 0.7 2.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 EMG45845.1 - 6e-08 32.6 0.4 1.8e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 GRAM domain EF-hand_6 PF13405.6 EMG45845.1 - 5.1e-05 22.9 2.1 0.1 12.6 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain Vps36_ESCRT-II PF11605.8 EMG45845.1 - 0.00047 20.3 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EF-hand_7 PF13499.6 EMG45845.1 - 0.00077 19.9 2.0 1.9 9.0 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EMG45845.1 - 0.0034 16.8 2.8 1.1 9.0 0.1 3.2 3 0 0 3 3 3 2 EF hand ANAPC8 PF04049.13 EMG45845.1 - 0.12 12.5 0.4 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 DUF1770 PF08589.10 EMG45847.1 - 2.3e-05 25.3 0.8 0.00033 21.6 0.1 2.1 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) RNA_pol_A_bac PF01000.26 EMG45848.1 - 6.6e-31 107.0 0.0 1.1e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EMG45848.1 - 9.4e-17 60.2 0.0 1.2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_biosynth PF00977.21 EMG45849.1 - 1.8e-14 53.8 0.0 2.6e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF4602 PF15375.6 EMG45850.1 - 1.1 9.6 26.2 75 3.6 26.2 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4602) Cnd2 PF05786.14 EMG45851.1 - 2.1e-118 397.1 38.6 2.6e-118 396.8 38.6 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EMG45851.1 - 5.5e-05 23.3 3.4 0.00026 21.2 0.4 2.9 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Glyco_hydro_16 PF00722.21 EMG45852.1 - 6e-47 159.4 0.6 1.2e-46 158.4 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ndc1_Nup PF09531.10 EMG45852.1 - 9.3 4.8 17.9 15 4.2 17.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HCO3_cotransp PF00955.21 EMG45853.1 - 2.5e-79 267.5 13.9 9.8e-44 150.0 8.7 2.0 1 1 1 2 2 2 2 HCO3- transporter family Asparaginase_2 PF01112.18 EMG45854.1 - 7.1e-25 87.7 0.0 9.5e-17 61.0 0.0 2.7 2 1 0 2 2 2 2 Asparaginase Ribosomal_L24e PF01246.20 EMG45855.1 - 1e-29 102.5 0.1 1e-29 102.5 0.1 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 EMG45855.1 - 0.13 11.8 2.3 0.18 11.4 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ribosomal_L7Ae PF01248.26 EMG45856.1 - 6.2e-24 83.6 0.0 7e-24 83.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DASH_Spc34 PF08657.10 EMG45857.1 - 1.5e-30 106.9 14.8 6.8e-21 75.2 3.9 2.2 1 1 1 2 2 2 2 DASH complex subunit Spc34 LemA PF04011.12 EMG45857.1 - 0.00013 21.8 1.7 0.00029 20.7 0.6 2.1 2 0 0 2 2 2 1 LemA family OmpH PF03938.14 EMG45857.1 - 0.0063 16.9 0.6 0.013 15.9 0.6 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DMPK_coil PF08826.10 EMG45857.1 - 0.011 15.9 0.4 0.038 14.1 0.4 1.9 1 0 0 1 1 1 0 DMPK coiled coil domain like HAUS6_N PF14661.6 EMG45857.1 - 0.074 12.6 0.1 0.086 12.4 0.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PKcGMP_CC PF16808.5 EMG45857.1 - 0.21 11.5 6.5 0.81 9.6 0.4 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Med9 PF07544.13 EMG45857.1 - 0.31 11.1 6.5 0.42 10.7 1.6 3.2 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.20 EMG45857.1 - 0.67 9.9 4.7 0.5 10.3 0.6 2.6 2 1 0 2 2 2 0 Prefoldin subunit Peptidase_M22 PF00814.25 EMG45858.1 - 4.3e-85 285.7 0.0 5.2e-85 285.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EMG45858.1 - 0.036 13.7 0.0 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus MutL PF13941.6 EMG45858.1 - 0.039 12.6 0.0 0.055 12.1 0.0 1.3 1 0 0 1 1 1 0 MutL protein DnaJ PF00226.31 EMG45859.1 - 3.8e-19 68.6 1.2 3.8e-18 65.4 0.9 2.5 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 EMG45859.1 - 6.8e-06 25.8 0.1 2.2e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EMG45859.1 - 0.007 16.2 0.1 0.014 15.2 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4523) XS PF03468.14 EMG45859.1 - 0.12 12.6 0.6 0.58 10.5 0.1 2.4 2 1 1 3 3 3 0 XS domain Malate_DH PF12434.8 EMG45859.1 - 0.35 10.9 2.2 3.5 7.7 0.1 2.6 2 0 0 2 2 2 0 Malate dehydrogenase enzyme DUF543 PF04418.12 EMG45860.1 - 1.3e-31 108.4 0.1 1.6e-31 108.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Acatn PF13000.7 EMG45861.1 - 1.7e-189 630.9 26.4 3e-122 408.9 14.5 2.6 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 FecCD PF01032.18 EMG45861.1 - 0.06 12.3 4.7 0.12 11.3 0.1 3.2 4 0 0 4 4 4 0 FecCD transport family Phage_holin_4_1 PF05105.12 EMG45861.1 - 0.28 11.3 3.7 0.38 10.9 0.1 2.8 3 0 0 3 3 3 0 Bacteriophage holin family SNF2_N PF00176.23 EMG45862.1 - 3.1e-54 184.0 0.2 5.6e-54 183.2 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMG45862.1 - 5.6e-15 55.6 0.0 7.1e-14 52.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG45862.1 - 1.5e-09 38.1 0.0 3.4e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMG45862.1 - 1e-06 28.6 0.0 2.8e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EMG45862.1 - 9.8e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase UCR_UQCRX_QCR9 PF05365.12 EMG45863.1 - 1.1e-20 73.3 3.0 1.2e-20 73.2 3.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like SBDS_C PF09377.10 EMG45864.1 - 6.8e-32 109.9 4.3 1.2e-31 109.1 4.3 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EMG45864.1 - 9.2e-32 109.0 4.4 1.7e-31 108.1 2.3 2.1 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SUV3_C PF12513.8 EMG45864.1 - 0.29 11.1 1.1 0.67 9.9 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal RAC_head PF16717.5 EMG45865.1 - 1.5e-22 80.4 10.7 1.5e-22 80.4 10.7 3.5 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 EMG45865.1 - 6.3e-18 64.7 0.1 2.3e-17 62.9 0.1 2.1 1 0 0 1 1 1 1 DnaJ domain RR_TM4-6 PF06459.12 EMG45865.1 - 2.3 8.0 19.3 2 8.2 14.4 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 EMG45865.1 - 5.1 7.1 13.0 2.6 8.0 8.3 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region IPP-2 PF04979.14 EMG45866.1 - 2.7e-22 79.9 7.4 2.7e-22 79.9 7.4 2.0 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) WD40 PF00400.32 EMG45867.1 - 1.8e-36 123.5 14.7 0.00015 22.5 0.0 10.8 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG45867.1 - 2.3e-09 37.4 3.5 0.74 10.1 0.0 7.2 6 2 2 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain YmzC PF14157.6 EMG45867.1 - 0.13 12.4 2.5 7.3 6.8 0.0 4.5 4 0 0 4 4 4 0 YmzC-like protein Pyrid_oxidase_2 PF13883.6 EMG45868.1 - 8.7e-51 172.2 0.0 1.2e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Med20 PF08612.11 EMG45868.1 - 1.4e-41 142.4 0.0 1.8e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex MutS_V PF00488.21 EMG45869.1 - 5.1e-31 108.2 0.4 1e-30 107.2 0.4 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMG45869.1 - 8.2e-23 81.6 0.8 8.2e-23 81.6 0.8 1.5 2 0 0 2 2 2 1 MutS domain III T2SSE PF00437.20 EMG45869.1 - 0.037 13.1 0.4 0.19 10.8 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 EMG45869.1 - 0.051 13.6 0.9 0.18 11.8 0.0 2.4 2 1 1 3 3 3 0 AAA domain MutS_IV PF05190.18 EMG45869.1 - 0.08 13.3 0.3 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 MutS family domain IV AAA_23 PF13476.6 EMG45869.1 - 0.11 13.0 0.0 0.11 13.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EMG45869.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.29 EMG45870.1 - 5.7e-47 159.7 0.2 1.2e-46 158.7 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG45870.1 - 5.5e-21 75.0 0.0 2e-20 73.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EMG45870.1 - 8.8e-19 67.5 0.0 3.3e-18 65.6 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EMG45870.1 - 6e-07 29.6 0.0 6e-07 29.6 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EMG45870.1 - 0.0041 17.3 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain Arm PF00514.23 EMG45871.1 - 9.4e-79 257.3 25.1 1e-11 44.5 0.1 11.2 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EMG45871.1 - 3.3e-23 81.7 8.3 0.00024 21.5 0.3 8.8 9 1 1 10 10 10 5 HEAT-like repeat HEAT_2 PF13646.6 EMG45871.1 - 4.1e-17 62.4 8.0 0.0011 19.3 0.0 6.9 3 2 1 5 5 5 4 HEAT repeats HEAT PF02985.22 EMG45871.1 - 2.4e-14 52.2 19.6 0.013 15.7 0.1 9.7 10 0 0 10 10 9 4 HEAT repeat Adaptin_N PF01602.20 EMG45871.1 - 2.6e-13 49.4 5.3 4.7e-08 32.0 1.2 2.3 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 EMG45871.1 - 1.3e-10 40.2 0.2 3.3e-10 38.8 0.2 1.8 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 EMG45871.1 - 5.7e-08 32.5 9.2 1e-05 25.1 2.8 3.1 2 1 0 3 3 3 2 Armadillo-like Vac14_Fab1_bd PF12755.7 EMG45871.1 - 1.2e-05 25.8 0.1 0.17 12.5 0.0 3.1 2 1 0 2 2 2 2 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.8 EMG45871.1 - 1.3e-05 25.3 3.4 0.27 11.3 0.0 5.3 3 1 4 7 7 7 1 V-ATPase subunit H Cnd1 PF12717.7 EMG45871.1 - 2.1e-05 24.7 9.0 0.21 11.6 0.3 5.0 1 1 5 6 6 6 3 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EMG45871.1 - 0.00012 22.0 11.1 0.026 14.5 0.1 5.4 2 1 2 5 5 5 1 Domain of unknown function (DUF3361) DUF5578 PF17741.1 EMG45871.1 - 0.0005 19.6 7.6 0.44 9.9 0.1 4.8 2 1 3 5 5 5 1 Family of unknown function (DUF5578) Tti2 PF10521.9 EMG45871.1 - 0.012 15.1 0.2 1.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Tti2 family DUF3110 PF11360.8 EMG45871.1 - 0.11 12.7 0.0 5.2 7.3 0.0 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF3110) Snf7 PF03357.21 EMG45872.1 - 2.3e-15 56.6 22.0 3.8e-15 55.9 22.0 1.3 1 0 0 1 1 1 1 Snf7 DUF234 PF03008.14 EMG45872.1 - 0.057 13.9 0.4 0.56 10.7 0.0 2.7 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function FBA_2 PF07735.17 EMG45872.1 - 0.1 12.8 0.3 0.1 12.8 0.3 3.0 3 0 0 3 3 3 0 F-box associated Iron_permease PF04120.12 EMG45872.1 - 0.99 9.2 6.1 2.4 7.9 6.1 1.7 1 0 0 1 1 1 0 Low affinity iron permease GvpG PF05120.12 EMG45872.1 - 2.5 8.2 8.8 3.1 7.9 7.3 1.9 1 1 0 1 1 1 0 Gas vesicle protein G Enkurin PF13864.6 EMG45872.1 - 6.6 7.2 14.1 0.14 12.6 1.3 2.7 1 1 0 2 2 2 0 Calmodulin-binding SGL PF08450.12 EMG45873.1 - 9e-77 258.0 0.3 1.1e-76 257.7 0.3 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 EMG45873.1 - 0.0085 16.1 0.2 1.3 9.1 0.0 3.1 3 1 0 3 3 3 2 Domain of unknown function (DUF5074) D123 PF07065.14 EMG45874.1 - 1.1e-102 343.3 9.7 1.3e-102 343.1 9.7 1.0 1 0 0 1 1 1 1 D123 Cpn60_TCP1 PF00118.24 EMG45875.1 - 6.2e-150 500.1 14.5 7.6e-150 499.8 14.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AbrB_C PF18277.1 EMG45875.1 - 0.27 10.9 1.7 0.94 9.2 0.1 2.8 3 1 1 4 4 4 0 AbrB C-terminal domain Sas10 PF09368.10 EMG45876.1 - 2e-30 105.1 12.7 7.9e-30 103.2 12.7 2.1 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EMG45876.1 - 0.00032 21.3 0.6 0.00032 21.3 0.6 3.2 3 1 0 3 3 3 1 Sas10/Utp3/C1D family Methyltransf_12 PF08242.12 EMG45876.1 - 0.081 13.7 2.6 0.62 10.8 2.5 2.6 1 1 0 1 1 1 0 Methyltransferase domain DUF3085 PF11284.8 EMG45876.1 - 1.9 8.9 4.9 4.9 7.5 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) RNA_pol_Rpc4 PF05132.14 EMG45877.1 - 1.1e-18 68.0 1.8 1.1e-18 68.0 1.8 3.5 3 1 0 3 3 3 1 RNA polymerase III RPC4 Binary_toxB PF03495.14 EMG45878.1 - 0.077 13.2 1.7 0.47 10.7 0.2 2.5 2 0 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain FSA_C PF10479.9 EMG45878.1 - 0.89 7.6 13.3 1.1 7.2 13.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Aldedh PF00171.22 EMG45879.1 - 1.9e-130 435.5 0.0 2.3e-130 435.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family hDGE_amylase PF14701.6 EMG45880.1 - 4.8e-170 566.4 1.4 7.7e-170 565.7 1.4 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EMG45880.1 - 1e-125 419.7 0.0 1.9e-125 418.8 0.0 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EMG45880.1 - 2.7e-74 250.0 0.0 7.2e-74 248.6 0.0 1.7 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EMG45880.1 - 3.6e-26 91.1 2.7 7.9e-26 90.0 2.7 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 EMG45880.1 - 0.0026 17.4 0.3 0.0072 15.9 0.2 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain F-box PF00646.33 EMG45881.1 - 0.13 12.2 0.6 0.36 10.8 0.6 1.8 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.6 EMG45884.1 - 5.4e-05 22.9 0.3 0.00014 21.5 0.3 1.7 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 EMG45884.1 - 0.0036 17.6 2.7 0.03 14.8 0.2 2.6 2 1 0 2 2 2 1 Leucine Rich Repeat LRR_4 PF12799.7 EMG45884.1 - 0.0067 16.8 2.7 0.074 13.5 0.2 2.3 1 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMG45884.1 - 0.19 11.8 1.5 1 9.6 0.1 2.2 2 0 0 2 2 2 0 Leucine Rich repeat Glyco_hydro_18 PF00704.28 EMG45885.1 - 4.2e-26 92.4 0.5 6e-25 88.6 0.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Flocculin_t3 PF13928.6 EMG45885.1 - 2.9e-10 40.5 20.4 2.9e-10 40.5 20.4 6.5 4 2 2 6 6 6 1 Flocculin type 3 repeat CDC45 PF02724.14 EMG45885.1 - 1.3 7.2 15.4 2.2 6.4 15.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.13 EMG45885.1 - 2.1 6.8 22.6 2.8 6.4 22.6 1.0 1 0 0 1 1 1 0 Utp14 protein LAP1C PF05609.12 EMG45885.1 - 2.4 7.2 21.0 3.3 6.7 21.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Lin-8 PF03353.15 EMG45885.1 - 6.7 6.2 16.7 9.7 5.7 16.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 EMG45885.1 - 8.5 4.4 27.6 13 3.8 27.6 1.2 1 0 0 1 1 1 0 Nop14-like family SAGA-Tad1 PF12767.7 EMG45885.1 - 9.2 5.9 7.6 16 5.1 7.6 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TFIIF_alpha PF05793.12 EMG45885.1 - 10 4.6 31.8 13 4.2 31.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Amidase PF01425.21 EMG45886.1 - 6.7e-90 302.2 0.0 9.3e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 Amidase Linker_histone PF00538.19 EMG45887.1 - 6e-23 81.0 0.2 6e-23 81.0 0.2 1.9 2 1 0 2 2 2 1 linker histone H1 and H5 family FMO-like PF00743.19 EMG45888.1 - 2.6e-28 98.8 1.3 2e-15 56.3 0.9 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMG45888.1 - 2.3e-15 56.7 0.1 4.8e-09 35.9 0.1 3.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMG45888.1 - 1.7e-12 47.2 0.0 1.2e-08 34.6 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMG45888.1 - 1e-07 32.0 0.1 1.5e-05 25.0 0.1 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EMG45888.1 - 7e-06 25.4 0.1 0.0015 17.7 0.0 3.5 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EMG45888.1 - 1.3e-05 25.3 0.0 3.8e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMG45888.1 - 0.0003 20.5 0.0 0.031 13.9 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMG45888.1 - 0.015 14.6 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EMG45888.1 - 0.049 14.2 0.4 3.9 8.1 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EMG45888.1 - 0.066 13.3 0.0 0.94 9.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 EMG45888.1 - 0.074 12.3 0.0 4.3 6.5 0.0 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase LRR_8 PF13855.6 EMG45889.1 - 0.0086 15.8 3.5 0.0086 15.8 3.5 6.7 7 1 1 8 8 8 1 Leucine rich repeat LRR_4 PF12799.7 EMG45889.1 - 0.023 15.1 0.3 0.023 15.1 0.3 8.1 6 2 3 9 9 9 0 Leucine Rich repeats (2 copies) NUP PF06516.11 EMG45890.1 - 6.1e-05 22.4 0.1 6.9e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) RINGv PF12906.7 EMG45891.1 - 6.1e-18 64.7 10.0 9.6e-18 64.1 10.0 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EMG45891.1 - 0.0054 17.0 9.7 0.0097 16.2 9.7 1.4 1 0 0 1 1 1 1 Ring finger domain COX5B PF01215.19 EMG45891.1 - 0.029 14.1 0.1 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb FANCL_C PF11793.8 EMG45891.1 - 0.082 13.1 6.0 0.18 12.0 6.0 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain YyzF PF14116.6 EMG45891.1 - 0.42 10.7 2.6 11 6.1 0.3 2.5 2 0 0 2 2 2 0 YyzF-like protein Zf_RING PF16744.5 EMG45891.1 - 1.5 9.0 7.3 5.6 7.1 7.3 1.8 1 1 1 2 2 2 0 KIAA1045 RING finger Cys_Knot_tox PF17486.2 EMG45891.1 - 4.9 7.4 7.9 27 5.1 7.9 2.0 1 1 1 2 2 2 0 Cystine knot toxins zf-RING_4 PF14570.6 EMG45891.1 - 7.3 6.5 7.2 13 5.7 7.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TFIID-18kDa PF02269.16 EMG45892.1 - 2.6e-17 62.6 0.4 4.2e-17 61.9 0.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EMG45892.1 - 6.7e-06 26.0 0.1 1.6e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 EMG45892.1 - 0.01 16.2 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 CENP-S protein CDC45 PF02724.14 EMG45892.1 - 0.14 10.4 6.2 0.15 10.3 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SRP72 PF08492.12 EMG45892.1 - 7.7 7.0 10.3 25 5.4 4.9 2.5 2 0 0 2 2 2 0 SRP72 RNA-binding domain p450 PF00067.22 EMG45893.1 - 2.1e-49 168.5 0.0 2.9e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SinI PF08671.10 EMG45893.1 - 0.07 12.9 0.5 0.15 11.8 0.5 1.6 1 0 0 1 1 1 0 Anti-repressor SinI Redoxin PF08534.10 EMG45894.1 - 7.5e-18 64.7 0.0 7.5e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EMG45894.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 EMG45896.1 - 3.8e-16 59.0 0.0 5.5e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EMG45896.1 - 0.00012 22.4 0.0 0.00019 21.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 EMG45896.1 - 0.0019 18.0 0.1 0.38 10.5 0.1 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 EMG45896.1 - 0.0025 17.8 0.0 0.0051 16.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin domain GST_N_3 PF13417.6 EMG45896.1 - 0.0063 16.9 0.0 0.0087 16.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.20 EMG45896.1 - 0.015 15.2 0.2 0.018 15.1 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 EMG45896.1 - 0.018 15.2 0.5 1.1 9.4 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.6 EMG45896.1 - 0.029 14.8 0.3 0.058 13.8 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain GST_N_2 PF13409.6 EMG45896.1 - 0.065 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RNA_lig_T4_1 PF09511.10 EMG45897.1 - 3.1e-77 259.3 0.3 6.6e-77 258.3 0.3 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EMG45897.1 - 6.5e-64 215.0 2.8 1.8e-63 213.6 2.8 1.8 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 EMG45897.1 - 7.6e-34 117.3 0.1 2.4e-33 115.7 0.1 1.9 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_ligase PF09414.10 EMG45897.1 - 0.0015 18.9 0.2 0.0039 17.5 0.2 1.7 1 0 0 1 1 1 1 RNA ligase ABC_tran PF00005.27 EMG45897.1 - 0.081 13.4 0.4 5.2 7.6 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 EMG45897.1 - 0.12 12.6 0.0 0.77 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Exo70 PF03081.15 EMG45898.1 - 1.6e-65 221.6 14.3 1.6e-65 221.6 14.3 2.0 2 0 0 2 2 2 1 Exo70 exocyst complex subunit RPAP3_C PF13877.6 EMG45898.1 - 0.15 12.6 3.8 6 7.5 0.1 3.9 2 1 1 3 3 3 0 Potential Monad-binding region of RPAP3 DUF948 PF06103.11 EMG45898.1 - 0.28 11.5 2.6 2.1 8.6 0.3 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 EMG45898.1 - 1.8 8.7 12.1 0.39 10.9 3.6 3.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MutL_C PF08676.11 EMG45899.1 - 9e-31 106.6 0.0 4.4e-30 104.4 0.0 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EMG45899.1 - 1.4e-26 92.5 0.2 2.7e-26 91.6 0.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EMG45899.1 - 6.4e-13 48.7 0.2 1.6e-12 47.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EMG45899.1 - 2.2e-06 28.2 0.3 8.3e-06 26.3 0.3 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glutaredoxin PF00462.24 EMG45900.1 - 6.6e-20 71.1 0.0 9.9e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.20 EMG45900.1 - 0.0019 18.0 0.1 0.32 10.7 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain DUF836 PF05768.14 EMG45900.1 - 0.0036 17.7 0.0 0.0066 16.8 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 EMG45900.1 - 0.0096 16.1 2.1 0.69 10.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_9 PF14595.6 EMG45900.1 - 0.0098 15.7 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMG45900.1 - 0.035 14.6 0.1 0.055 13.9 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EMG45900.1 - 0.047 13.7 0.2 0.16 12.0 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin domain zf_C2H2_6 PF18450.1 EMG45900.1 - 1.3 8.8 4.0 8 6.3 0.0 2.4 2 0 0 2 2 2 0 Zinc Finger domain SMC_N PF02463.19 EMG45901.1 - 1.8e-16 60.3 38.0 5.9e-16 58.6 38.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMG45901.1 - 6.6e-07 30.0 107.1 1.2e-06 29.1 48.5 6.1 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 EMG45901.1 - 3.5e-05 23.8 1.4 3.5e-05 23.8 1.4 4.2 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMG45901.1 - 5e-05 23.2 40.5 5e-05 23.2 40.5 4.7 1 1 2 3 3 3 1 AAA ATPase domain SMC_hinge PF06470.13 EMG45901.1 - 0.00093 19.5 0.1 0.0056 17.0 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 EMG45901.1 - 0.0065 16.2 0.1 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EMG45901.1 - 0.1 13.1 0.1 0.1 13.1 0.1 5.2 3 2 1 4 4 4 0 ABC transporter TPR_MLP1_2 PF07926.12 EMG45901.1 - 1 9.4 84.3 0.45 10.6 12.3 7.0 5 1 1 6 6 6 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 EMG45901.1 - 5.8 5.4 81.0 0.076 11.7 21.0 5.2 4 1 1 5 5 5 0 AAA domain 60KD_IMP PF02096.20 EMG45902.1 - 5e-27 94.8 4.0 9e-27 94.0 4.0 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein Tom5 PF10642.9 EMG45902.1 - 0.095 12.7 0.9 0.47 10.5 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Mnd1 PF03962.15 EMG45902.1 - 0.18 12.1 0.4 0.39 11.0 0.4 1.5 1 0 0 1 1 1 0 Mnd1 HTH domain DUF4745 PF15923.5 EMG45902.1 - 0.27 11.2 4.0 0.27 11.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4745) Epimerase PF01370.21 EMG45903.1 - 4.3e-19 68.9 0.1 8.6e-19 68.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG45903.1 - 2.4e-13 49.7 0.0 3.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMG45903.1 - 1.9e-06 27.2 0.1 0.029 13.5 0.0 2.9 2 1 1 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.6 EMG45903.1 - 2.7e-05 24.1 0.0 0.00015 21.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMG45903.1 - 4.6e-05 23.0 2.5 0.00025 20.6 2.5 2.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMG45903.1 - 7.6e-05 22.4 1.8 0.00092 18.8 1.5 2.4 2 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EMG45903.1 - 0.00013 21.3 0.1 0.0014 17.9 0.7 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EMG45903.1 - 0.00093 18.7 0.1 0.002 17.6 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG45903.1 - 0.0045 16.9 0.1 0.012 15.6 0.1 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMG45903.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 EMG45903.1 - 0.11 11.6 0.1 0.19 10.8 0.1 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain Pro_isomerase PF00160.21 EMG45904.1 - 4.3e-47 160.3 0.2 4.9e-47 160.1 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_8 PF13855.6 EMG45905.1 - 6.6e-10 38.6 14.1 0.00055 19.7 0.5 6.1 5 1 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EMG45905.1 - 1.2e-07 31.9 29.2 0.0059 17.0 1.0 8.4 8 1 1 9 9 9 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMG45905.1 - 4.8 7.5 15.7 1.1 9.4 0.1 6.7 8 0 0 8 8 8 0 Leucine Rich repeat RhoGAP PF00620.27 EMG45906.1 - 7.5e-37 126.5 0.0 2.7e-36 124.7 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.20 EMG45906.1 - 4.2e-18 65.5 0.9 4e-17 62.4 0.9 2.9 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGEF PF00617.19 EMG45906.1 - 3e-16 60.1 4.1 1.4e-13 51.4 0.1 3.8 4 0 0 4 4 4 2 RasGEF domain PH PF00169.29 EMG45906.1 - 0.0096 16.4 0.0 0.055 14.0 0.0 2.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EMG45906.1 - 0.015 15.7 0.2 1.4 9.3 0.1 3.0 2 0 0 2 2 2 0 Pleckstrin homology domain Dpoe2NT PF12213.8 EMG45906.1 - 0.078 13.3 0.9 0.21 11.9 0.2 2.1 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal SDA1 PF05285.12 EMG45907.1 - 0.0013 18.2 2.3 0.0013 18.2 2.3 1.2 1 0 0 1 1 1 1 SDA1 DNA_pol_phi PF04931.13 EMG45907.1 - 0.003 15.8 15.1 0.0034 15.6 15.1 1.2 1 0 0 1 1 1 1 DNA polymerase phi CENP-B_dimeris PF09026.10 EMG45907.1 - 0.0077 16.6 20.2 0.018 15.4 20.2 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.8 EMG45907.1 - 0.012 15.8 17.9 0.012 15.8 17.9 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.9 EMG45907.1 - 0.014 14.6 18.8 0.021 14.0 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF5523 PF17661.1 EMG45907.1 - 0.041 13.6 6.6 0.057 13.1 6.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) NOA36 PF06524.12 EMG45907.1 - 0.047 13.0 11.7 0.056 12.8 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EMG45907.1 - 0.089 12.8 5.6 0.13 12.3 5.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.12 EMG45907.1 - 0.19 11.1 8.3 0.24 10.7 8.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 EMG45907.1 - 0.26 10.4 5.1 0.35 10.0 5.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cwf_Cwc_15 PF04889.12 EMG45907.1 - 0.29 10.8 12.8 0.42 10.3 12.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TipE PF16972.5 EMG45907.1 - 0.33 10.1 2.0 0.38 9.9 2.0 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE TFB6 PF17110.5 EMG45907.1 - 0.49 10.1 4.2 0.7 9.6 4.2 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 EMG45907.1 - 0.88 7.8 9.4 1.1 7.5 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EMG45907.1 - 1.1 7.8 8.0 1.2 7.5 8.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 EMG45907.1 - 1.4 8.5 12.8 1.8 8.1 12.8 1.2 1 0 0 1 1 1 0 PPP4R2 SURF2 PF05477.11 EMG45907.1 - 2.2 7.9 8.9 3.1 7.4 8.9 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) p450 PF00067.22 EMG45908.1 - 3.4e-50 171.1 0.0 4.6e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SPG48 PF14764.6 EMG45908.1 - 0.042 14.3 0.3 11 6.5 0.1 2.5 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking NifU_N PF01592.16 EMG45909.1 - 5.1e-58 194.8 0.1 6.1e-58 194.5 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain LRR_4 PF12799.7 EMG45910.1 - 0.022 15.2 8.7 2.6 8.6 0.8 4.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) SAC3_GANP PF03399.16 EMG45910.1 - 0.035 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 SAC3/GANP family DUF1071 PF06378.11 EMG45910.1 - 0.1 12.2 0.0 0.4 10.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Ribosomal_L5e PF17144.4 EMG45911.1 - 6e-81 270.2 1.0 8.5e-80 266.5 0.0 2.2 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EMG45911.1 - 4.8e-33 114.0 8.1 4.8e-33 114.0 8.1 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 EMG45911.1 - 0.003 17.9 1.4 0.0039 17.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thr_synth_N PF14821.6 EMG45911.1 - 0.0074 16.5 1.1 0.41 10.9 0.0 3.0 2 1 1 3 3 3 1 Threonine synthase N terminus NAC PF01849.18 EMG45911.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 NAC domain DUF1160 PF06648.11 EMG45911.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) PUB PF09409.10 EMG45911.1 - 0.068 13.1 1.1 2.9 7.9 0.3 2.7 3 0 0 3 3 3 0 PUB domain SPT6_acidic PF14632.6 EMG45911.1 - 1.7 9.3 6.0 4 8.1 6.0 1.6 1 0 0 1 1 1 0 Acidic N-terminal SPT6 MFS_1 PF07690.16 EMG45912.1 - 2.8e-33 115.3 35.3 2.8e-33 115.3 35.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG45912.1 - 6.7e-15 54.9 10.3 6.7e-15 54.9 10.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Pam17 PF08566.10 EMG45912.1 - 0.43 10.4 3.6 0.77 9.6 0.6 2.6 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF202 PF02656.15 EMG45912.1 - 2.9 8.4 0.0 2.9 8.4 0.0 4.3 3 2 1 4 4 4 0 Domain of unknown function (DUF202) HAMP PF00672.25 EMG45913.1 - 7.4e-33 112.7 13.7 9.2e-10 38.8 1.5 6.3 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 EMG45913.1 - 2.7e-30 105.2 0.2 7.4e-30 103.7 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMG45913.1 - 7.2e-26 90.6 0.7 3e-25 88.5 0.2 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EMG45913.1 - 2.9e-17 62.5 0.7 2.9e-17 62.5 0.7 3.4 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain SWIRM PF04433.17 EMG45913.1 - 0.01 16.2 0.5 0.031 14.6 0.5 1.8 1 0 0 1 1 1 0 SWIRM domain IL32 PF15225.6 EMG45913.1 - 0.017 15.5 0.5 14 6.1 0.0 3.8 4 0 0 4 4 4 0 Interleukin 32 DUF1843 PF08898.10 EMG45913.1 - 0.042 14.4 4.0 11 6.6 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) DUF4279 PF14106.6 EMG45913.1 - 0.046 13.9 0.1 6.8 6.9 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4279) DUF3829 PF12889.7 EMG45913.1 - 1.4 8.3 22.3 2.1 7.8 6.2 5.5 5 1 0 5 5 5 0 Protein of unknown function (DUF3829) STAT_int PF02865.17 EMG45913.1 - 3.9 7.9 9.4 1.5 9.3 0.4 3.7 3 0 0 3 3 3 0 STAT protein, protein interaction domain Aminotran_3 PF00202.21 EMG45914.1 - 1.8e-118 395.7 0.0 2.4e-118 395.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EMG45914.1 - 0.00033 20.0 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase AA_permease_2 PF13520.6 EMG45915.1 - 9.5e-49 166.4 55.7 1.2e-48 166.0 55.7 1.1 1 0 0 1 1 1 1 Amino acid permease AAA_26 PF13500.6 EMG45915.1 - 2.4e-45 154.8 0.0 3.6e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AA_permease PF00324.21 EMG45915.1 - 3.1e-10 39.3 47.4 4.3e-10 38.8 47.4 1.1 1 0 0 1 1 1 1 Amino acid permease Chitin_synth_1 PF01644.17 EMG45916.1 - 9.4e-75 250.1 1.2 1.8e-74 249.1 1.2 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 EMG45916.1 - 1.5e-25 89.9 3.5 3.9e-20 72.0 0.0 2.7 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 EMG45916.1 - 5.2e-25 87.2 0.0 1.6e-24 85.6 0.0 1.9 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 EMG45916.1 - 2.2e-09 37.6 3.6 2.2e-09 37.5 0.0 2.7 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMG45916.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF2070 PF09843.9 EMG45916.1 - 2.3 6.4 10.3 5.3 5.2 10.3 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF805 PF05656.14 EMG45916.1 - 5.7 7.4 16.8 0.15 12.5 8.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF805) RCC1 PF00415.18 EMG45917.1 - 1.6e-66 220.7 0.0 1.2e-12 48.2 0.0 7.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMG45917.1 - 1.5e-40 136.2 19.1 1.4e-07 31.1 0.2 6.8 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 EMG45917.1 - 0.014 15.8 0.3 13 6.2 0.0 4.2 4 1 0 4 4 4 0 SUKH-3 immunity protein Hira PF07569.11 EMG45917.1 - 0.017 14.9 0.0 5.8 6.6 0.0 3.2 3 1 1 4 4 4 0 TUP1-like enhancer of split DNA_pol_B PF00136.21 EMG45918.1 - 9.2e-150 499.3 2.6 1.6e-149 498.6 2.6 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EMG45918.1 - 1e-91 307.6 1.0 1.6e-91 306.9 1.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EMG45918.1 - 5.1e-19 68.5 3.2 1.2e-18 67.4 3.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EMG45918.1 - 0.0021 17.0 1.8 0.15 10.9 0.1 2.9 2 1 0 3 3 3 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 EMG45918.1 - 0.013 15.5 0.1 0.082 12.9 0.1 2.4 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 EMG45918.1 - 0.02 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 EMG45918.1 - 4.1 7.4 6.7 23 5.0 0.9 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) D-ser_dehydrat PF14031.6 EMG45919.1 - 2.7e-21 76.0 0.0 6.4e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EMG45919.1 - 4.9e-13 49.2 0.1 6.7e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain GST_N PF02798.20 EMG45920.1 - 1.3e-15 57.5 0.0 3.7e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMG45920.1 - 1.4e-11 44.4 0.0 2.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMG45920.1 - 1.6e-11 44.4 0.0 2.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMG45920.1 - 1.9e-09 37.6 0.0 3.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMG45920.1 - 1e-08 35.4 0.0 2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMG45920.1 - 0.00027 20.9 0.0 0.00044 20.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GAS PF13851.6 EMG45921.1 - 0.0054 16.1 14.5 0.0064 15.9 14.5 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TSA PF03249.13 EMG45921.1 - 0.047 12.5 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Type specific antigen Lant_dehydr_C PF14028.6 EMG45921.1 - 0.087 12.3 0.3 0.095 12.2 0.3 1.1 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Allexi_40kDa PF05549.11 EMG45921.1 - 0.31 10.5 5.6 0.37 10.3 5.6 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein UPF0242 PF06785.11 EMG45921.1 - 3.2 7.8 15.3 4.4 7.4 15.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 EMG45921.1 - 3.7 6.3 3.9 3.9 6.3 3.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Tropomyosin PF00261.20 EMG45922.1 - 3.2e-05 23.4 13.4 0.056 12.8 0.9 3.0 3 0 0 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.9 EMG45922.1 - 0.00015 21.8 9.1 0.00015 21.8 9.1 2.4 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 EMG45922.1 - 0.0006 18.6 8.1 0.00073 18.3 8.1 1.1 1 0 0 1 1 1 1 AAA domain NPV_P10 PF05531.12 EMG45922.1 - 0.0018 18.7 1.9 0.24 11.9 0.2 2.5 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 EMG45922.1 - 0.0048 15.8 7.7 0.0048 15.8 7.7 2.0 1 1 0 2 2 2 1 Spc7 kinetochore protein Histone_HNS PF00816.21 EMG45922.1 - 0.0089 16.8 4.9 0.16 12.8 1.6 2.4 1 1 1 2 2 2 1 H-NS histone family Bacillus_HBL PF05791.11 EMG45922.1 - 0.012 15.4 4.4 0.013 15.3 2.5 1.9 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) IFT57 PF10498.9 EMG45922.1 - 0.027 13.5 12.9 0.011 14.7 5.8 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 COG2 PF06148.11 EMG45922.1 - 0.066 13.3 12.1 0.91 9.6 0.6 2.9 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HrpB7 PF09486.10 EMG45922.1 - 0.08 13.3 2.4 0.28 11.6 2.4 1.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) YnfE PF17452.2 EMG45922.1 - 0.24 11.7 4.4 18 5.7 0.0 3.3 2 1 1 3 3 3 0 Uncharacterized YnfE-like DUF5082 PF16888.5 EMG45922.1 - 0.26 11.6 9.2 1.2 9.5 4.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) CCDC-167 PF15188.6 EMG45922.1 - 0.29 11.5 13.8 1.2 9.5 3.1 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 HAUS6_N PF14661.6 EMG45922.1 - 0.53 9.8 8.6 0.2 11.2 3.3 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Vps51 PF08700.11 EMG45922.1 - 0.54 10.4 10.7 0.91 9.7 1.5 3.1 2 1 1 3 3 3 0 Vps51/Vps67 Atg14 PF10186.9 EMG45922.1 - 0.56 9.2 9.1 0.99 8.4 9.1 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 EMG45922.1 - 0.56 10.8 10.7 1.2 9.8 0.7 3.3 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 MetOD2 PF18548.1 EMG45922.1 - 0.69 10.1 8.5 1.5 9.0 0.3 3.5 2 1 1 3 3 3 0 Metanogen output domain 2 DUF1664 PF07889.12 EMG45922.1 - 0.74 9.9 8.4 0.99 9.4 2.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 EMG45922.1 - 1.1 9.7 13.3 0.44 11.0 4.4 2.1 1 1 1 2 2 2 0 Fez1 DUF4446 PF14584.6 EMG45922.1 - 1.3 9.0 8.4 0.23 11.4 1.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Tup_N PF08581.10 EMG45922.1 - 1.4 9.3 12.8 2.1 8.7 1.0 3.3 2 1 1 3 3 3 0 Tup N-terminal eIF3_subunit PF08597.10 EMG45922.1 - 1.7 8.5 9.3 3.9 7.3 8.6 1.8 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Laminin_II PF06009.12 EMG45922.1 - 2.7 8.0 10.6 2.2 8.3 4.1 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF4795 PF16043.5 EMG45922.1 - 3 7.4 11.0 2.4 7.7 4.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) HAUS-augmin3 PF14932.6 EMG45922.1 - 3.3 7.2 13.6 7.4 6.1 1.2 2.6 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Fib_alpha PF08702.10 EMG45922.1 - 5.1 7.3 12.6 4.9 7.3 5.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 EMG45922.1 - 9.5 6.5 13.6 6.7 7.0 8.6 2.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NEMP PF10225.9 EMG45923.1 - 0.0019 17.9 1.3 0.0026 17.5 1.3 1.1 1 0 0 1 1 1 1 NEMP family Flu_NS2 PF00601.19 EMG45923.1 - 0.017 15.4 1.3 0.028 14.7 0.3 1.9 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) Carbpep_Y_N PF05388.11 EMG45923.1 - 0.044 14.3 2.8 0.067 13.7 2.8 1.4 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Prominin PF05478.11 EMG45923.1 - 3 5.7 9.4 3.2 5.6 9.4 1.0 1 0 0 1 1 1 0 Prominin Fzo_mitofusin PF04799.13 EMG45923.1 - 4.4 6.8 10.1 5.1 6.6 9.5 1.5 1 1 0 1 1 1 0 fzo-like conserved region DUF4337 PF14235.6 EMG45923.1 - 5.5 7.1 10.7 6 7.0 10.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) TMPIT PF07851.13 EMG45923.1 - 7.9 5.6 11.4 12 5.1 11.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein Dynamin_N PF00350.23 EMG45925.1 - 3.9e-41 140.9 0.0 3.9e-41 140.9 0.0 2.4 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EMG45925.1 - 2.2e-05 24.5 0.0 8.8e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 EMG45925.1 - 0.003 16.8 2.3 0.003 16.8 2.3 3.7 3 2 0 3 3 3 1 Dynamin central region AAA_16 PF13191.6 EMG45925.1 - 0.079 13.3 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 EMG45925.1 - 0.094 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Uds1 PF15456.6 EMG45925.1 - 4.4 7.5 10.8 7.8 6.7 1.7 3.2 3 1 0 3 3 3 0 Up-regulated During Septation WD40 PF00400.32 EMG45926.1 - 0.0002 22.1 0.1 0.092 13.7 0.0 5.0 6 0 0 6 6 6 1 WD domain, G-beta repeat bPH_4 PF06713.11 EMG45926.1 - 0.028 14.5 0.8 0.13 12.4 0.4 2.3 2 0 0 2 2 2 0 Bacterial PH domain Sfi1 PF08457.10 EMG45927.1 - 6.7e-23 81.0 52.4 1.2e-13 50.5 26.8 3.4 2 1 1 3 3 3 3 Sfi1 spindle body protein Erp_C PF06780.11 EMG45927.1 - 0.013 15.5 0.4 0.052 13.6 0.4 2.1 1 0 0 1 1 1 0 Erp protein C-terminus Glyco_transf_22 PF03901.17 EMG45928.1 - 8.4e-38 130.7 13.9 1.1e-37 130.3 13.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CRPA PF05745.11 EMG45928.1 - 6.2 6.8 7.0 1.8 8.5 3.3 2.0 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) cobW PF02492.19 EMG45929.1 - 1.1e-41 142.4 0.8 1.4e-41 142.0 0.8 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EMG45929.1 - 2.9e-08 33.5 0.0 6.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MMR_HSR1 PF01926.23 EMG45929.1 - 0.003 17.6 0.3 0.014 15.5 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EMG45929.1 - 0.0064 16.2 0.3 0.018 14.7 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EMG45929.1 - 0.011 16.3 0.2 0.022 15.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMG45929.1 - 0.028 14.9 0.0 0.063 13.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EMG45929.1 - 0.031 14.3 0.1 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMG45929.1 - 0.034 14.5 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EMG45929.1 - 0.071 13.6 2.3 0.2 12.2 2.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EMG45929.1 - 0.095 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EMG45929.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 EMG45929.1 - 0.19 11.6 1.2 6.5 6.6 0.2 2.5 2 1 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EMG45929.1 - 0.58 9.7 2.6 11 5.5 2.6 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Tim54 PF11711.8 EMG45930.1 - 7.8e-130 433.0 1.9 3.8e-129 430.7 1.9 1.8 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DASH_Duo1 PF08651.10 EMG45931.1 - 1.1e-15 57.1 3.4 1.1e-15 57.1 3.4 1.9 2 0 0 2 2 2 1 DASH complex subunit Duo1 bZIP_1 PF00170.21 EMG45931.1 - 0.0013 18.8 6.2 0.21 11.7 2.8 2.4 2 0 0 2 2 2 2 bZIP transcription factor DASH_Dad2 PF08654.10 EMG45931.1 - 0.0015 18.9 2.1 0.0049 17.3 2.1 1.8 1 1 0 1 1 1 1 DASH complex subunit Dad2 APG6_N PF17675.1 EMG45931.1 - 0.0039 17.7 1.2 0.007 16.9 1.2 1.4 1 1 0 1 1 1 1 Apg6 coiled-coil region TBK1_CCD1 PF18394.1 EMG45931.1 - 0.055 13.0 2.3 0.065 12.8 0.1 1.8 2 0 0 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 Laminin_II PF06009.12 EMG45931.1 - 0.15 12.1 5.6 3.9 7.5 0.2 2.1 1 1 1 2 2 2 0 Laminin Domain II Med31 PF05669.12 EMG45932.1 - 8.2e-39 131.5 4.7 1.1e-38 131.1 4.7 1.1 1 0 0 1 1 1 1 SOH1 Acetyltransf_6 PF13480.7 EMG45933.1 - 2e-07 31.2 0.0 4.7e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SNARE_assoc PF09335.11 EMG45933.1 - 4.5 7.8 8.4 0.61 10.6 0.2 3.2 3 0 0 3 3 3 0 SNARE associated Golgi protein Spot_14 PF07084.12 EMG45934.1 - 0.033 14.3 0.4 0.033 14.3 0.4 1.9 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 Zwint PF15556.6 EMG45934.1 - 0.06 12.8 7.0 0.09 12.3 6.5 1.5 1 1 0 1 1 1 0 ZW10 interactor Nup88 PF10168.9 EMG45934.1 - 0.27 9.0 8.4 0.38 8.5 8.4 1.2 1 0 0 1 1 1 0 Nuclear pore component DHHW PF14286.6 EMG45934.1 - 0.45 9.8 9.9 0.035 13.4 4.2 1.8 1 1 1 2 2 2 0 DHHW protein Peptidase_M20 PF01546.28 EMG45935.1 - 3.2e-31 108.7 0.0 4.2e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMG45935.1 - 1.5e-08 34.5 0.1 4.5e-08 33.0 0.1 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMG45935.1 - 1.5e-05 24.8 0.0 4.2e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 Phage_G PF02306.15 EMG45935.1 - 0.15 11.8 1.3 0.45 10.2 0.1 2.3 3 0 0 3 3 3 0 Major spike protein (G protein) Pkinase PF00069.25 EMG45936.1 - 1.4e-66 224.5 0.0 2.9e-66 223.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45936.1 - 7.3e-47 159.8 0.0 1.2e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG45936.1 - 3.1e-07 30.0 0.0 0.00026 20.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EMG45936.1 - 0.089 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_1 PF00536.30 EMG45936.1 - 0.15 12.5 0.7 0.37 11.3 0.3 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) GlpM PF06942.12 EMG45937.1 - 0.0068 16.8 0.1 0.0075 16.7 0.1 1.1 1 0 0 1 1 1 1 GlpM protein RRN9 PF10680.9 EMG45938.1 - 6.6e-08 32.7 7.0 0.002 18.3 0.3 2.6 1 1 1 2 2 2 2 RNA polymerase I specific transcription initiation factor CLTH PF10607.9 EMG45939.1 - 6.5e-30 104.0 10.1 6.5e-30 104.0 10.1 2.5 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EMG45939.1 - 2.1e-06 27.4 0.1 5.3e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 LisH PH_3 PF14593.6 EMG45939.1 - 0.0065 16.6 0.3 0.019 15.1 0.1 1.8 2 0 0 2 2 2 1 PH domain DUF4611 PF15387.6 EMG45939.1 - 8.4 6.7 8.8 6.8 7.0 5.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PMT PF02366.18 EMG45940.1 - 7.3e-82 274.6 22.5 7.3e-82 274.6 22.5 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EMG45940.1 - 6.7e-54 182.5 10.8 6.7e-54 182.5 10.8 2.3 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EMG45940.1 - 3.2e-20 72.8 0.8 7e-20 71.6 0.8 1.5 1 0 0 1 1 1 1 MIR domain Ferric_reduct PF01794.19 EMG45941.1 - 6.4e-26 90.9 11.3 6.4e-26 90.9 11.3 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EMG45941.1 - 4.2e-24 84.7 0.0 7.6e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ribosomal_L10 PF00466.20 EMG45942.1 - 9.5e-05 22.5 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Methyltransf_4 PF02390.17 EMG45943.1 - 3.2e-61 205.8 0.9 3.2e-61 205.8 0.0 1.4 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EMG45943.1 - 0.00041 19.9 0.0 0.0047 16.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EMG45943.1 - 0.0013 19.4 0.0 0.0028 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMG45943.1 - 0.0036 17.1 0.0 0.0075 16.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG45943.1 - 0.025 15.3 0.1 0.088 13.6 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_32 PF13679.6 EMG45943.1 - 0.041 13.9 0.1 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EMG45943.1 - 0.16 12.7 0.0 1.9 9.2 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain Reticulon PF02453.17 EMG45944.1 - 1.9e-36 125.4 4.4 2.7e-36 124.9 4.4 1.2 1 0 0 1 1 1 1 Reticulon Halogen_Hydrol PF10112.9 EMG45944.1 - 0.7 9.9 4.6 8.1 6.4 0.5 2.1 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein 7TM_GPCR_Srw PF10324.9 EMG45946.1 - 0.01 15.2 0.1 0.01 15.1 0.1 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw TssO PF17561.2 EMG45946.1 - 0.02 15.0 0.1 0.025 14.7 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO Asp PF00026.23 EMG45947.1 - 2.9e-59 201.1 4.5 4.5e-59 200.4 4.5 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMG45947.1 - 3.1e-12 47.1 0.2 1.1e-10 42.0 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EMG45947.1 - 0.005 17.4 0.1 2.7 8.6 0.0 3.3 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EMG45947.1 - 0.0071 17.0 7.9 1.3 9.7 0.1 3.8 4 1 0 4 4 4 2 Aspartyl protease AAA_11 PF13086.6 EMG45949.1 - 0.0036 17.1 1.0 0.01 15.6 0.1 1.9 2 0 0 2 2 2 1 AAA domain POTRA_2 PF08479.11 EMG45949.1 - 0.13 12.1 0.2 18 5.3 0.0 2.5 2 0 0 2 2 2 0 POTRA domain, ShlB-type Aconitase PF00330.20 EMG45950.1 - 3.2e-112 375.9 0.0 3.5e-111 372.5 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMG45950.1 - 5.3e-30 104.4 0.0 1.2e-29 103.3 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EMG45950.1 - 0.00095 18.0 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Pkinase PF00069.25 EMG45951.1 - 2.5e-66 223.7 0.0 7.2e-61 205.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45951.1 - 1.2e-32 113.2 0.0 4.4e-31 108.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EMG45951.1 - 1.4e-18 66.4 0.0 3.4e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 EMG45951.1 - 1.4e-05 24.6 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMG45951.1 - 9.9e-05 21.8 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EMG45951.1 - 0.00083 18.4 0.1 0.0032 16.5 0.1 2.0 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EMG45951.1 - 0.0062 16.5 0.4 0.1 12.5 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EMG45951.1 - 0.11 12.0 0.2 0.44 10.0 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL F1F0-ATPsyn_F PF10791.9 EMG45952.1 - 3e-38 130.2 0.2 4.7e-38 129.6 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi LSM PF01423.22 EMG45952.1 - 3.7e-17 61.8 0.8 4.8e-17 61.4 0.8 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EMG45952.1 - 0.0034 17.5 0.2 0.0076 16.4 0.2 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 EMG45952.1 - 0.036 13.7 0.2 0.13 12.0 0.2 1.8 2 0 0 2 2 2 0 Hfq protein WRW PF10206.9 EMG45952.1 - 0.04 14.3 0.0 0.066 13.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f LSM14 PF12701.7 EMG45952.1 - 0.048 13.8 0.1 0.069 13.3 0.1 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain p450 PF00067.22 EMG45953.1 - 3.8e-64 217.1 0.0 5.1e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YlbE PF14003.6 EMG45953.1 - 0.049 14.1 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 YlbE-like protein Nup192 PF11894.8 EMG45954.1 - 0 1721.7 67.3 0 1721.6 67.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF3510 PF12022.8 EMG45954.1 - 0.13 12.6 2.0 29 5.1 0.5 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) PEPCK_ATP PF01293.20 EMG45955.1 - 6e-217 720.9 0.0 6.9e-217 720.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 EMG45955.1 - 0.077 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMG45955.1 - 0.22 11.9 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain p450 PF00067.22 EMG45956.1 - 2.2e-63 214.6 0.0 3.1e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lipase_GDSL_lke PF16255.5 EMG45956.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Glyco_hydro_3 PF00933.21 EMG45957.1 - 7.8e-58 196.3 0.0 1e-57 195.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_10 PF13673.7 EMG45957.1 - 0.013 15.5 0.1 0.056 13.4 0.1 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMG45957.1 - 0.017 15.4 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EMG45957.1 - 0.17 12.0 0.8 2.2 8.4 0.1 2.6 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.18 EMG45958.1 - 1.8e-21 76.4 0.1 3.4e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG45958.1 - 1.5e-06 28.3 5.6 1.5e-06 28.3 5.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.28 EMG45959.1 - 1.2e-27 97.4 0.5 4e-27 95.8 0.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 XPG_I PF00867.18 EMG45960.1 - 9.6e-28 96.4 0.2 1.3e-26 92.8 0.0 2.5 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EMG45960.1 - 0.00015 22.2 0.0 0.0004 20.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain GEN1_C PF18380.1 EMG45960.1 - 0.12 13.3 0.0 0.4 11.6 0.0 1.9 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Aminotran_1_2 PF00155.21 EMG45963.1 - 2e-43 148.9 0.0 2.5e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMG45963.1 - 1.6e-05 24.0 0.0 9.9e-05 21.5 0.0 2.0 1 1 1 2 2 2 1 Aminotransferase class-V Alliinase_C PF04864.13 EMG45963.1 - 1.9e-05 23.7 0.0 3.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Allinase Beta_elim_lyase PF01212.21 EMG45963.1 - 0.0005 19.4 0.0 0.00072 18.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EMG45963.1 - 0.0026 16.3 0.0 0.0037 15.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 EMG45963.1 - 0.014 14.2 0.0 0.025 13.4 0.0 1.5 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase FTHFS PF01268.19 EMG45964.1 - 5.5e-244 810.5 0.2 6.9e-244 810.2 0.2 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EMG45964.1 - 1.1e-66 223.1 3.8 1.7e-66 222.5 1.0 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EMG45964.1 - 1.7e-37 128.2 0.5 3.7e-37 127.1 0.5 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SUB1_ProdP9 PF18213.1 EMG45964.1 - 0.0053 16.6 0.2 0.015 15.2 0.2 1.7 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 OCD_Mu_crystall PF02423.15 EMG45964.1 - 0.015 14.3 0.3 0.024 13.6 0.3 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family AdoHcyase_NAD PF00670.21 EMG45964.1 - 0.021 14.9 1.5 0.96 9.5 1.5 2.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMG45964.1 - 0.19 11.1 0.4 1.6 8.1 0.1 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EMG45965.1 - 9.3e-43 146.3 1.7 1.1e-42 146.1 1.7 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMG45965.1 - 1.2e-10 41.3 5.4 3.3e-09 36.6 5.4 2.0 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMG45965.1 - 4e-09 36.3 0.3 7.2e-09 35.4 0.3 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EMG45965.1 - 3.2e-06 27.6 0.3 5.4e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EMG45965.1 - 9.2e-06 25.9 0.3 1.8e-05 25.0 0.3 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EMG45965.1 - 1.4e-05 25.2 0.3 2.7e-05 24.3 0.3 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 EMG45965.1 - 0.00016 20.8 0.5 0.00022 20.4 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMG45965.1 - 0.00025 20.3 0.0 0.018 14.2 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein Ldh_1_N PF00056.23 EMG45965.1 - 0.0013 18.9 0.8 0.0025 17.9 0.5 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EMG45965.1 - 0.014 14.5 0.1 0.048 12.8 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain DXP_reductoisom PF02670.16 EMG45965.1 - 0.042 14.6 1.0 0.064 14.0 1.0 1.4 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase EPL1 PF10513.9 EMG45966.1 - 1.7e-26 93.5 21.1 1.3e-24 87.4 5.7 2.6 2 0 0 2 2 2 2 Enhancer of polycomb-like Phage_Gp23 PF10669.9 EMG45966.1 - 2.7 8.3 11.3 12 6.2 11.3 2.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) WD40 PF00400.32 EMG45967.1 - 9.3e-07 29.5 0.1 0.067 14.1 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Pkinase PF00069.25 EMG45968.1 - 5.9e-60 202.9 1.4 7.3e-59 199.3 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG45968.1 - 5.4e-29 101.3 0.7 1.1e-28 100.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Hpr_kinase_C PF07475.12 EMG45968.1 - 0.25 10.9 1.3 0.43 10.1 1.3 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain APH PF01636.23 EMG45968.1 - 0.3 11.0 0.1 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family ATG2_CAD PF13329.6 EMG45968.1 - 0.46 10.2 2.8 0.35 10.6 0.5 1.8 2 0 0 2 2 2 0 Autophagy-related protein 2 CAD motif Spt20 PF12090.8 EMG45968.1 - 0.69 9.5 24.0 0.18 11.4 18.5 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 EMG45968.1 - 0.9 9.5 18.4 1.7 8.5 18.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 EMG45968.1 - 1.1 9.3 11.7 2.1 8.4 11.7 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Med3 PF11593.8 EMG45968.1 - 7.8 5.6 19.6 0.056 12.6 10.4 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal FH2 PF02181.23 EMG45969.1 - 5.7e-58 196.8 33.2 2.3e-40 138.9 2.5 4.4 3 1 1 4 4 4 3 Formin Homology 2 Domain Drf_GBD PF06371.13 EMG45969.1 - 1.6e-19 70.2 8.0 8e-18 64.7 1.1 4.7 5 0 0 5 5 5 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EMG45969.1 - 3.8e-13 49.5 16.1 5.3e-13 49.0 0.7 4.3 4 0 0 4 4 4 2 Diaphanous FH3 Domain SlyX PF04102.12 EMG45969.1 - 0.022 15.3 15.1 0.1 13.2 1.8 5.5 4 1 1 5 5 5 0 SlyX DUF4558 PF15104.6 EMG45969.1 - 0.053 13.6 0.2 0.053 13.6 0.2 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4558) ASFV_J13L PF05568.11 EMG45969.1 - 0.18 11.5 1.5 0.45 10.2 1.5 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein PIF1 PF05970.14 EMG45970.1 - 6.5e-50 170.3 5.1 2.2e-46 158.7 5.1 2.9 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EMG45970.1 - 4.9e-21 75.3 0.0 7.4e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMG45970.1 - 5.9e-09 36.4 0.1 3.1e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 EMG45970.1 - 1.6e-08 33.0 0.0 6.8e-06 24.3 0.0 2.2 2 0 0 2 2 2 2 Helicase AAA_7 PF12775.7 EMG45970.1 - 6.7e-05 22.5 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 EMG45970.1 - 0.00013 21.8 0.1 0.00034 20.4 0.1 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EMG45970.1 - 0.00016 22.0 1.2 0.00057 20.2 0.3 2.4 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EMG45970.1 - 0.00033 19.8 0.0 0.00063 18.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 EMG45970.1 - 0.00072 19.4 0.4 0.19 11.4 0.0 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EMG45970.1 - 0.0016 17.8 0.1 0.0053 16.1 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EMG45970.1 - 0.0052 17.2 0.1 0.016 15.6 0.1 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMG45970.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 EMG45970.1 - 0.014 15.1 0.0 0.083 12.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 EMG45970.1 - 0.03 13.8 0.0 0.077 12.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 EMG45970.1 - 0.039 13.7 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMG45970.1 - 0.057 13.9 0.1 0.24 11.9 0.1 2.0 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EMG45970.1 - 0.062 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EMG45970.1 - 0.19 12.3 1.1 0.71 10.4 0.2 2.4 3 0 0 3 3 3 0 AAA domain Hyphal_reg_CWP PF11765.8 EMG45971.1 - 4.2e-31 108.1 1.8 4.6e-31 108.0 1.8 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal LRR_8 PF13855.6 EMG45977.1 - 0.00015 21.5 0.9 0.00015 21.5 0.9 6.7 7 1 0 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 EMG45977.1 - 0.019 15.4 3.1 0.019 15.4 3.1 9.5 7 3 2 10 10 10 0 Leucine Rich repeats (2 copies) DUF3709 PF12493.8 EMG45978.1 - 0.18 11.9 0.6 0.23 11.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3709) Dna2 PF08696.11 EMG45979.1 - 1.3e-37 129.6 1.5 5.6e-37 127.5 1.5 2.2 1 0 0 1 1 1 1 DNA replication factor Dna2 PDDEXK_1 PF12705.7 EMG45979.1 - 7.6e-08 32.6 0.1 1.4e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_11 PF13086.6 EMG45979.1 - 9.7e-07 28.8 8.1 0.00016 21.5 0.0 3.2 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 EMG45979.1 - 3.4e-05 23.7 0.0 5.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EMG45979.1 - 4.7e-05 23.3 1.0 0.00015 21.6 0.0 2.4 3 0 0 3 3 3 1 Helicase PhoH PF02562.16 EMG45979.1 - 0.0011 18.5 0.1 0.0042 16.6 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 EMG45979.1 - 0.0072 16.3 0.1 0.0072 16.3 0.1 3.7 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit FAM209 PF15206.6 EMG45979.1 - 0.022 14.6 0.3 0.32 10.8 0.1 2.8 2 0 0 2 2 2 0 FAM209 family IstB_IS21 PF01695.17 EMG45979.1 - 0.023 14.5 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EMG45979.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EMG45979.1 - 0.06 13.4 0.0 0.06 13.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain PH_15 PF17339.2 EMG45979.1 - 0.15 12.0 1.4 1.3 9.0 0.1 3.2 3 1 0 3 3 3 0 PH domain CbiA PF01656.23 EMG45979.1 - 0.25 11.4 0.1 0.25 11.4 0.1 3.2 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1884 PF08967.10 EMG45979.1 - 0.38 11.0 4.0 1 9.6 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1884) zf-C2H2 PF00096.26 EMG45980.1 - 1e-08 35.1 45.3 0.22 12.1 0.5 10.7 10 0 0 10 10 10 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG45980.1 - 1.4e-07 31.7 43.8 3.6 8.7 0.8 11.5 11 0 0 11 11 11 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EMG45980.1 - 0.0072 16.1 9.0 0.58 10.0 0.2 4.5 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-met PF12874.7 EMG45980.1 - 0.11 12.9 0.2 0.11 12.9 0.2 6.0 8 0 0 8 8 8 0 Zinc-finger of C2H2 type DUF1894 PF08979.11 EMG45980.1 - 1.4 9.4 4.2 16 5.9 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1894) zf_ZIC PF18366.1 EMG45980.1 - 4.8 7.4 11.2 12 6.1 0.0 5.2 6 0 0 6 6 6 0 Zic proteins zinc finger domain His_Phos_1 PF00300.22 EMG45981.1 - 1.4e-36 126.0 0.0 2.9e-36 125.0 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) E1-E2_ATPase PF00122.20 EMG45982.1 - 3.3e-33 114.7 10.0 8.6e-29 100.3 0.1 4.0 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMG45982.1 - 1.6e-21 76.9 6.8 1.6e-21 76.9 6.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EMG45982.1 - 3e-19 68.9 0.0 6e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMG45982.1 - 5.6e-19 69.3 0.0 1.1e-17 65.0 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMG45982.1 - 1.9e-13 49.9 0.0 5e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMG45982.1 - 0.00038 20.3 0.6 0.0027 17.5 1.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_18 PF13238.6 EMG45983.1 - 6.9e-25 88.1 0.1 6.9e-25 88.1 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EMG45983.1 - 0.002 18.6 0.3 0.0056 17.1 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 EMG45983.1 - 0.0042 17.5 0.0 0.0042 17.5 0.0 2.9 2 1 1 3 3 2 1 AAA domain RNA_helicase PF00910.22 EMG45983.1 - 0.0053 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 EMG45983.1 - 0.01 15.7 4.1 0.91 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EMG45983.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Paf1 PF03985.13 EMG45983.1 - 0.014 14.4 14.1 0.017 14.1 14.1 1.2 1 0 0 1 1 1 0 Paf1 AAA_33 PF13671.6 EMG45983.1 - 0.019 15.1 0.4 2.6 8.2 0.1 2.8 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.6 EMG45983.1 - 0.025 14.8 0.0 0.047 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 EMG45983.1 - 0.029 13.8 0.0 0.029 13.8 0.0 1.9 2 1 1 3 3 3 0 Chromatin associated protein KTI12 AAA PF00004.29 EMG45983.1 - 0.035 14.5 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EMG45983.1 - 0.088 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EMG45983.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2347 PF09804.9 EMG45983.1 - 0.48 10.0 2.4 0.74 9.3 2.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Cwf_Cwc_15 PF04889.12 EMG45983.1 - 0.59 9.8 22.1 0.78 9.4 22.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EMG45983.1 - 1.4 7.1 23.2 1.6 6.8 23.2 1.1 1 0 0 1 1 1 0 Nop14-like family Hpr_kinase_C PF07475.12 EMG45983.1 - 3.2 7.2 5.8 4.4 6.8 0.0 2.5 3 0 0 3 3 2 0 HPr Serine kinase C-terminal domain AAA_23 PF13476.6 EMG45983.1 - 3.8 8.0 15.1 6.7 7.2 15.1 1.4 1 1 0 1 1 1 0 AAA domain Presenilin PF01080.17 EMG45983.1 - 4.1 6.1 5.8 4.7 5.9 5.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 EMG45983.1 - 4.5 6.6 17.4 6.6 6.1 17.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 EMG45983.1 - 6.4 6.1 26.2 7.8 5.8 26.2 1.1 1 0 0 1 1 1 0 SDA1 V_ATPase_I PF01496.19 EMG45983.1 - 6.5 4.5 6.2 7.9 4.3 6.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Heme_oxygenase PF01126.20 EMG45984.1 - 4.6e-20 72.3 1.6 8.9e-20 71.4 1.6 1.4 1 1 0 1 1 1 1 Heme oxygenase Sugar_tr PF00083.24 EMG45985.1 - 1.1e-80 271.8 21.9 1.2e-80 271.6 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG45985.1 - 2.6e-19 69.4 28.1 6e-19 68.2 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMG45985.1 - 8.4e-07 27.9 1.2 8.4e-07 27.9 1.2 3.2 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_4 PF06779.14 EMG45985.1 - 0.00022 20.6 1.2 0.00022 20.6 1.2 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EMG45985.1 - 0.0025 16.3 0.3 0.0025 16.3 0.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cellulase PF00150.18 EMG45986.1 - 6.2e-30 104.6 1.7 1e-29 103.9 1.7 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 EMG45986.1 - 0.0018 18.0 0.9 0.0018 18.0 0.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4038) NatB_MDM20 PF09797.9 EMG45988.1 - 2.4e-42 145.3 9.6 2.4e-42 145.3 9.6 2.6 3 1 0 3 3 3 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EMG45988.1 - 0.0055 17.2 0.9 0.8 10.3 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Choline_transpo PF04515.12 EMG45989.1 - 2.1e-79 267.1 24.6 2.1e-79 267.1 24.6 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter DUF5472 PF17566.2 EMG45989.1 - 0.1 12.6 3.4 1.5 8.8 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5472) Metallophos_2 PF12850.7 EMG45990.1 - 4.7e-11 43.1 0.1 1.1e-10 41.9 0.0 1.7 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain MCM_bind PF09739.9 EMG45990.1 - 0.0021 16.6 4.5 0.0054 15.2 3.6 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance replisome factor RNA_pol_Rpc4 PF05132.14 EMG45990.1 - 0.043 14.2 1.8 0.072 13.5 1.4 1.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Pox_Ag35 PF03286.14 EMG45990.1 - 0.072 12.9 7.8 0.1 12.4 7.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CPSF100_C PF13299.6 EMG45990.1 - 0.12 12.6 3.4 0.21 11.8 3.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Afi1 PF07792.12 EMG45990.1 - 0.15 12.6 7.8 0.24 11.9 7.8 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking HSP90 PF00183.18 EMG45990.1 - 0.16 10.9 9.3 0.2 10.5 9.3 1.1 1 0 0 1 1 1 0 Hsp90 protein SDA1 PF05285.12 EMG45990.1 - 0.22 10.9 15.4 0.28 10.6 15.4 1.1 1 0 0 1 1 1 0 SDA1 XAP5 PF04921.14 EMG45990.1 - 0.39 10.5 9.3 0.56 10.0 9.3 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Ferlin_C PF16165.5 EMG45990.1 - 0.41 10.6 2.1 0.66 9.9 2.1 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Nop14 PF04147.12 EMG45990.1 - 0.46 8.6 14.6 0.56 8.3 14.6 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EMG45990.1 - 0.76 8.5 1.9 0.94 8.2 1.9 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 EMG45990.1 - 1.7 7.3 8.0 2.4 6.9 8.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.16 EMG45990.1 - 2.4 7.3 9.3 3.4 6.8 9.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 EMG45990.1 - 2.5 6.3 12.6 3.4 5.9 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EMG45990.1 - 3.9 5.9 8.7 4.7 5.6 8.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Glyco_hydro_72 PF03198.14 EMG45991.1 - 2.2e-151 503.5 9.9 3e-151 503.1 9.9 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EMG45991.1 - 4.7e-29 100.9 5.5 1.4e-28 99.4 5.5 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EMG45991.1 - 1.6e-06 27.8 1.1 1.9e-05 24.3 1.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EMG45991.1 - 0.00027 20.2 2.3 0.00073 18.7 2.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain HMGL-like PF00682.19 EMG45993.1 - 6.6e-84 281.6 0.0 9.2e-84 281.1 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EMG45993.1 - 1.3e-25 89.8 0.2 2.6e-25 88.9 0.2 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ribosomal_L13 PF00572.18 EMG45994.1 - 7.2e-12 45.7 0.5 1.9e-09 37.8 0.0 2.5 2 1 1 3 3 3 2 Ribosomal protein L13 Gsf2 PF11055.8 EMG45996.1 - 9e-146 485.4 0.1 1.1e-145 485.2 0.1 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 HTH_micro PF17007.5 EMG45996.1 - 0.011 14.7 0.2 0.019 13.8 0.2 1.4 1 0 0 1 1 1 0 HTH-like RRM_1 PF00076.22 EMG45997.1 - 3.2e-42 142.2 0.0 1.6e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMG45997.1 - 0.0014 18.7 0.0 0.91 9.7 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EMG45997.1 - 0.0031 17.1 0.1 0.16 11.5 0.0 2.7 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EMG45997.1 - 0.016 15.2 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain Macoilin PF09726.9 EMG45997.1 - 0.073 11.6 39.4 0.11 11.0 39.4 1.3 1 0 0 1 1 1 0 Macoilin family Kelch_3 PF13415.6 EMG45998.1 - 2.5e-33 113.7 0.8 8.9e-11 41.8 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EMG45998.1 - 1.6e-32 110.9 13.8 5.2e-09 35.9 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EMG45998.1 - 2.7e-32 110.5 8.7 7.2e-09 35.5 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EMG45998.1 - 3.9e-24 84.1 5.2 1.7e-08 34.4 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EMG45998.1 - 1.3e-20 72.5 8.3 1.3e-07 31.2 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EMG45998.1 - 5.6e-20 70.7 5.4 1.7e-08 33.9 0.1 5.4 5 0 0 5 5 5 2 Kelch motif RAG2 PF03089.14 EMG45998.1 - 0.0015 17.6 0.0 0.1 11.5 0.0 3.1 3 0 0 3 3 3 1 Recombination activating protein 2 RPW8 PF05659.11 EMG45998.1 - 0.002 17.8 2.8 0.002 17.8 2.8 4.0 3 1 1 4 4 4 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 SHE3 PF17078.5 EMG45998.1 - 0.0028 17.4 15.0 0.0028 17.4 15.0 4.7 2 1 3 5 5 5 1 SWI5-dependent HO expression protein 3 Arrestin_N PF00339.29 EMG45999.1 - 3.2e-19 69.4 0.6 1.3e-18 67.5 0.0 2.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EMG45999.1 - 6.2e-09 36.4 0.2 1.7e-06 28.5 0.0 2.8 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 EMG45999.1 - 0.031 13.3 0.1 1.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 Calcyon PF06387.11 EMG45999.1 - 0.069 13.1 0.6 0.13 12.3 0.6 1.4 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) Menin PF05053.13 EMG45999.1 - 0.76 8.1 2.9 1.2 7.4 2.9 1.3 1 0 0 1 1 1 0 Menin Cpn60_TCP1 PF00118.24 EMG46001.1 - 6.4e-151 503.3 12.5 7.2e-151 503.1 12.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 EMG46001.1 - 0.006 16.9 0.0 0.054 13.8 0.0 2.4 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor Vps53_N PF04100.12 EMG46002.1 - 2.4e-50 171.6 25.4 1.4e-48 165.8 25.4 2.7 1 1 0 1 1 1 1 Vps53-like, N-terminal PRAI PF00697.22 EMG46002.1 - 1.1e-24 87.2 0.0 5.4e-23 81.8 0.0 2.6 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Vps54_N PF10475.9 EMG46002.1 - 0.00023 20.6 9.9 0.00023 20.6 9.9 2.7 2 1 1 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex CHASE6_C PF17150.4 EMG46002.1 - 0.34 11.6 3.3 5.6 7.7 1.2 3.3 2 1 1 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain NOP5NT PF08156.13 EMG46002.1 - 2.5 8.6 7.9 14 6.2 0.1 4.4 4 0 0 4 4 4 0 NOP5NT (NUC127) domain zf-C4H2 PF10146.9 EMG46002.1 - 3.9 7.7 8.5 1.6 9.0 4.5 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein WD40 PF00400.32 EMG46003.1 - 3.4e-55 182.8 18.4 4.4e-10 40.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EMG46003.1 - 8.8e-30 102.8 11.0 8.8e-30 102.8 11.0 2.2 2 0 0 2 2 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EMG46003.1 - 3.7e-18 65.6 0.0 0.00023 21.4 0.0 6.1 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMG46003.1 - 3.9e-07 29.3 0.1 0.79 8.6 0.0 4.4 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EMG46003.1 - 1.9e-06 27.4 0.1 0.083 12.2 0.0 4.8 4 1 1 5 5 5 1 WD40-like domain PD40 PF07676.12 EMG46003.1 - 0.00011 22.0 0.0 26 4.9 0.0 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EMG46003.1 - 0.00014 20.5 0.0 0.0038 15.8 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 EMG46003.1 - 0.00017 20.4 0.8 0.076 11.6 0.1 3.2 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Ret2_MD PF18528.1 EMG46003.1 - 0.019 15.4 0.0 17 5.8 0.0 3.5 1 1 2 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Nbas_N PF15492.6 EMG46003.1 - 0.097 12.0 0.2 3.6 6.8 0.0 3.0 1 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Ndc1_Nup PF09531.10 EMG46003.1 - 0.21 10.2 15.1 0.29 9.8 15.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MMR1 PF08505.10 EMG46003.1 - 0.22 11.8 18.4 0.37 11.0 18.4 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein V_ATPase_I PF01496.19 EMG46003.1 - 0.25 9.2 11.0 0.31 8.9 11.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RP-C_C PF11800.8 EMG46003.1 - 0.37 10.8 11.5 0.61 10.1 11.5 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region CCDC84 PF14968.6 EMG46003.1 - 0.63 9.6 15.1 1.9 8.0 15.5 1.6 2 0 0 2 2 2 0 Coiled coil protein 84 Spc7 PF08317.11 EMG46003.1 - 2 7.2 21.8 3 6.6 21.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 EMG46003.1 - 2.6 7.8 16.3 0.35 10.7 11.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) SARAF PF06682.12 EMG46003.1 - 3.3 7.3 11.3 5.5 6.5 11.3 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Hydin_ADK PF17213.3 EMG46003.1 - 4.2 7.6 11.4 7.9 6.7 11.4 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain eIF-3_zeta PF05091.12 EMG46003.1 - 4.3 6.2 17.0 6.2 5.7 17.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ALMT PF11744.8 EMG46003.1 - 7 5.4 11.5 9.7 4.9 11.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MDD_C PF18376.1 EMG46004.1 - 1.6e-62 210.5 0.4 5.7e-61 205.5 0.4 2.2 1 1 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EMG46004.1 - 9e-10 38.6 2.8 2.5e-09 37.3 0.8 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain Malic_M PF03949.15 EMG46005.1 - 4e-85 285.2 0.0 5.3e-85 284.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EMG46005.1 - 2.1e-59 200.4 0.0 4.9e-59 199.2 0.0 1.6 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain YojJ PF10372.9 EMG46005.1 - 0.14 12.2 0.0 0.67 10.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus AP_endonuc_2 PF01261.24 EMG46006.1 - 5e-37 127.4 0.0 6.8e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HTH_29 PF13551.6 EMG46007.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix RBR PF17208.3 EMG46007.1 - 0.025 15.3 0.1 0.04 14.6 0.1 1.4 1 0 0 1 1 1 0 RNA binding Region Nucleoporin2 PF04096.14 EMG46008.1 - 3.1e-44 150.7 0.0 6.1e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EMG46008.1 - 5.9e-23 81.5 390.4 2e-13 51.0 38.8 11.2 4 3 6 10 10 10 6 Nucleoporin FG repeat region EMA PF02488.15 EMG46008.1 - 0.27 10.9 2.3 0.45 10.1 2.3 1.2 1 0 0 1 1 1 0 Merozoite Antigen Glyco_transf_8 PF01501.20 EMG46009.1 - 1.4e-20 73.9 6.1 1.1e-19 71.0 6.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 EMG46009.1 - 0.019 14.9 0.1 0.03 14.3 0.1 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Rota_NS53 PF00981.17 EMG46009.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) UDG PF03167.19 EMG46010.1 - 2e-18 66.8 0.1 3.8e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily OST3_OST6 PF04756.13 EMG46011.1 - 5.7e-78 262.2 5.2 6.9e-78 262.0 5.2 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EMG46011.1 - 0.016 15.5 4.2 0.11 12.9 1.6 3.1 3 1 0 3 3 3 0 Thioredoxin-like EamA PF00892.20 EMG46012.1 - 3.8e-10 40.1 34.8 2.6e-07 30.9 5.9 3.2 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 EMG46012.1 - 1e-05 24.9 11.1 1e-05 24.9 11.1 1.8 2 0 0 2 2 2 1 UAA transporter family SLC35F PF06027.12 EMG46012.1 - 4.7e-05 23.1 13.5 7.6e-05 22.4 13.5 1.3 1 0 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 EMG46012.1 - 0.00016 21.0 4.8 0.00035 19.9 4.8 1.6 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport DUF3955 PF13127.6 EMG46012.1 - 0.0097 15.7 0.7 0.0097 15.7 0.7 4.6 4 1 0 4 4 4 2 Protein of unknown function (DUF3955) DOT1 PF08123.13 EMG46013.1 - 8.5e-70 234.4 0.1 2.2e-69 233.1 0.1 1.8 1 0 0 1 1 1 1 Histone methylation protein DOT1 SNF2_N PF00176.23 EMG46014.1 - 1.3e-74 251.0 0.5 2.3e-74 250.2 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EMG46014.1 - 1.1e-38 131.7 3.9 2.8e-38 130.4 1.6 3.0 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 EMG46014.1 - 3.1e-30 105.2 10.8 3.1e-30 105.2 10.8 3.8 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 EMG46014.1 - 1.4e-19 70.5 0.0 1.5e-18 67.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG46014.1 - 3.5e-12 46.6 2.6 3.8e-11 43.3 0.0 3.8 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 EMG46014.1 - 1.8e-06 28.0 0.1 0.012 15.8 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain DEAD PF00270.29 EMG46014.1 - 0.0012 18.7 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase PALP PF00291.25 EMG46015.1 - 1.5e-57 195.3 0.0 2.5e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FMO-like PF00743.19 EMG46015.1 - 3.9e-22 78.4 4.2 4.3e-13 48.5 0.7 2.5 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMG46015.1 - 9.7e-10 38.2 0.6 7e-09 35.4 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMG46015.1 - 0.083 12.2 1.2 0.22 10.7 0.1 2.2 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase Mqo PF06039.15 EMG46015.1 - 0.085 11.4 0.2 0.15 10.6 0.2 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) TRM13 PF05206.14 EMG46016.1 - 4 6.9 5.6 0.32 10.5 0.3 1.8 2 0 0 2 2 2 0 Methyltransferase TRM13 CLTH PF10607.9 EMG46017.1 - 2.9e-33 114.8 7.8 2.9e-33 114.8 7.8 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain FMO-like PF00743.19 EMG46017.1 - 2e-21 76.0 0.4 1.8e-13 49.8 0.4 2.4 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMG46017.1 - 1.6e-09 37.4 1.0 5.9e-09 35.6 1.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMG46017.1 - 3.9e-08 32.8 0.1 1e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 EMG46017.1 - 0.028 13.7 1.1 0.091 12.0 0.0 2.3 2 1 0 3 3 3 0 Flavin containing amine oxidoreductase DAO PF01266.24 EMG46017.1 - 0.082 12.5 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trypan_glycop PF00913.19 EMG46017.1 - 0.31 10.3 5.8 0.49 9.6 5.8 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) EAP30 PF04157.16 EMG46017.1 - 0.85 8.9 3.9 4.2 6.6 1.6 2.9 2 1 1 3 3 3 0 EAP30/Vps36 family FtsX_ECD PF18075.1 EMG46017.1 - 1.7 9.3 7.7 1.2 9.8 4.5 2.4 2 0 0 2 2 2 0 FtsX extracellular domain FAT PF02259.23 EMG46017.1 - 1.9 7.7 9.0 0.1 11.8 1.4 2.3 3 0 0 3 3 3 0 FAT domain IZUMO PF15005.6 EMG46017.1 - 8.4 6.9 11.7 3.8 8.0 7.2 2.6 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF2431 PF10354.9 EMG46018.1 - 5.6e-58 195.9 0.7 6.3e-58 195.7 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) NAD_binding_8 PF13450.6 EMG46019.1 - 0.0063 16.7 0.2 0.027 14.7 0.2 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMG46019.1 - 0.0073 16.3 0.0 0.0098 15.9 0.0 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding Candida_ALS_N PF11766.8 EMG46020.1 - 1.5e-90 302.8 11.8 1.8e-90 302.6 11.8 1.1 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Big_8 PF17961.1 EMG46020.1 - 0.0023 18.0 0.4 0.0058 16.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial Ig domain NAD_binding_8 PF13450.6 EMG46021.1 - 0.013 15.7 0.2 0.057 13.6 0.2 1.9 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMG46021.1 - 0.017 15.1 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding GDA1_CD39 PF01150.17 EMG46023.1 - 4.1e-82 276.1 0.9 2.8e-71 240.4 0.1 2.2 1 1 1 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 EMG46023.1 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family E1_UFD PF09358.10 EMG46024.1 - 0.095 13.4 2.5 0.85 10.4 0.4 3.2 2 0 0 2 2 2 0 Ubiquitin fold domain HARP PF07443.13 EMG46024.1 - 0.12 12.1 2.4 5.2 6.8 0.1 2.8 2 0 0 2 2 2 0 HepA-related protein (HARP) DUF1706 PF08020.11 EMG46024.1 - 0.27 11.2 8.5 0.12 12.3 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) FAM176 PF14851.6 EMG46024.1 - 1.2 8.8 12.1 2.6 7.7 0.2 2.2 2 0 0 2 2 2 0 FAM176 family BUD22 PF09073.10 EMG46024.1 - 2.5 7.4 12.5 4 6.7 5.9 2.1 2 0 0 2 2 2 0 BUD22 Spt5_N PF11942.8 EMG46024.1 - 4 8.5 19.1 0.32 12.0 2.2 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Fungal_trans PF04082.18 EMG46025.1 - 1.3e-73 247.3 10.2 1.3e-73 247.3 10.2 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EMG46025.1 - 2e-07 31.1 11.1 0.0016 18.8 3.6 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG46025.1 - 0.0016 19.1 7.8 0.27 12.2 2.0 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger FBA_3 PF08268.12 EMG46025.1 - 0.03 14.3 0.0 0.092 12.7 0.0 1.8 1 0 0 1 1 1 0 F-box associated domain zf_C2H2_ZHX PF18387.1 EMG46025.1 - 0.15 11.7 1.3 0.62 9.7 1.3 2.0 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF5345 PF17280.2 EMG46025.1 - 3.5 7.7 5.5 13 5.9 5.5 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Ribosomal_S8e PF01201.22 EMG46026.1 - 5.6e-45 152.9 0.2 9.3e-45 152.2 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3746 PF12562.8 EMG46026.1 - 0.099 12.6 0.2 0.28 11.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) HPD PF05044.12 EMG46026.1 - 0.18 11.7 0.3 0.18 11.7 0.3 1.8 2 0 0 2 2 2 0 Homeo-prospero domain Sas10_Utp3 PF04000.15 EMG46027.1 - 1.8e-14 54.1 4.4 1.8e-14 54.1 4.4 2.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family PRELI PF04707.14 EMG46027.1 - 0.034 14.0 0.1 0.067 13.0 0.1 1.5 1 0 0 1 1 1 0 PRELI-like family Pro_isomerase PF00160.21 EMG46028.1 - 9.8e-46 155.9 0.4 1.2e-45 155.6 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 EMG46029.1 - 7.2e-49 165.9 0.0 2.3e-48 164.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG46029.1 - 2.5e-30 105.1 0.0 1.2e-29 102.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG46029.1 - 0.0014 18.6 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EMG46029.1 - 0.049 13.0 0.1 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit NAD_kinase PF01513.21 EMG46030.1 - 2.2e-79 266.7 0.0 2.9e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EMG46030.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain LSPR PF06049.12 EMG46031.1 - 0.089 12.7 0.0 0.3 11.1 0.0 2.0 1 0 0 1 1 1 0 Coagulation Factor V LSPD Repeat DNA_pol_B PF00136.21 EMG46032.1 - 1.5e-98 330.5 2.6 2.7e-98 329.7 2.6 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EMG46032.1 - 1.3e-22 80.4 14.5 4.8e-14 52.2 2.7 2.7 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EMG46032.1 - 7.8e-10 39.1 11.1 7.8e-10 39.1 11.1 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Pkinase PF00069.25 EMG46033.1 - 1.3e-59 201.7 0.0 1.7e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG46033.1 - 1.4e-38 132.7 0.0 1.9e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG46033.1 - 3.1e-06 26.7 0.0 4.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EMG46033.1 - 0.00026 20.2 0.2 0.00098 18.3 0.1 1.8 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EMG46033.1 - 0.0065 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EMG46033.1 - 0.021 13.8 0.1 0.037 13.0 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EMG46033.1 - 0.14 11.1 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Radical_SAM_C PF16199.5 EMG46034.1 - 4.6e-32 109.9 0.0 9.4e-32 108.9 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EMG46034.1 - 2.7e-18 66.9 0.2 6.3e-18 65.7 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily MBA1 PF07961.11 EMG46035.1 - 5.5e-56 189.3 0.4 6.9e-56 188.9 0.4 1.1 1 0 0 1 1 1 1 MBA1-like protein LSPR PF06049.12 EMG46036.1 - 0.11 12.4 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 Coagulation Factor V LSPD Repeat zf-CCCH_4 PF18044.1 EMG46037.1 - 1.7e-11 43.6 11.2 2.1e-05 24.2 1.4 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 EMG46037.1 - 1.9e-10 40.4 10.4 7.8e-06 25.7 1.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EMG46037.1 - 6.3e-08 33.3 8.6 0.00093 19.9 0.3 3.1 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 EMG46037.1 - 1.2e-07 31.5 17.7 1.8e-05 24.6 3.3 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 EMG46037.1 - 8.6e-07 29.2 1.8 1.1e-06 28.8 0.4 1.9 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EMG46037.1 - 0.026 15.0 14.7 0.41 11.2 4.0 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger NOG1_N PF17835.1 EMG46038.1 - 7.6e-49 165.7 0.1 2.5e-48 164.0 0.1 2.0 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EMG46038.1 - 1.3e-26 92.3 2.3 4e-26 90.7 2.3 1.9 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EMG46038.1 - 1.1e-25 89.2 1.2 1.6e-25 88.6 0.2 1.9 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EMG46038.1 - 3.4e-16 59.3 0.0 1e-15 57.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMG46038.1 - 2.9e-10 39.9 0.0 6.3e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMG46038.1 - 0.0016 18.4 0.0 0.65 9.9 0.2 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EMG46038.1 - 0.044 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 EMG46038.1 - 0.075 13.1 1.7 8.2 6.5 0.0 3.2 2 2 1 3 3 3 0 Dynamin family MMR_HSR1_Xtn PF16897.5 EMG46038.1 - 0.14 12.2 1.6 1.7 8.7 0.2 2.8 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain Anp1 PF03452.14 EMG46040.1 - 2.1e-106 355.2 0.2 2.4e-106 355.0 0.2 1.0 1 0 0 1 1 1 1 Anp1 Glyco_transf_8 PF01501.20 EMG46040.1 - 0.0007 19.2 1.3 0.0011 18.5 0.5 1.5 1 1 0 2 2 2 1 Glycosyl transferase family 8 DUF2181 PF10223.9 EMG46040.1 - 0.05 13.1 0.2 0.67 9.4 0.7 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2181) Glycos_transf_2 PF00535.26 EMG46040.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 C1_4 PF07975.12 EMG46041.1 - 0.066 13.5 0.6 0.14 12.4 0.6 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain Zn_clus PF00172.18 EMG46042.1 - 2.1e-07 30.9 12.1 3.9e-07 30.1 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_C PF00043.25 EMG46043.1 - 6.9e-12 45.4 0.0 6.9e-12 45.4 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMG46043.1 - 3.9e-10 39.6 0.2 7.8e-10 38.6 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EF1G PF00647.19 EMG46043.1 - 1.7e-07 31.2 0.0 3.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C_3 PF14497.6 EMG46043.1 - 3.6e-07 30.3 0.0 3.6e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMG46043.1 - 3.7e-07 30.4 0.3 1.2e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMG46043.1 - 0.065 13.7 0.5 0.17 12.4 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain OAD_gamma PF04277.13 EMG46043.1 - 6.2 7.5 7.2 14 6.3 7.2 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Fungal_trans PF04082.18 EMG46044.1 - 5.9e-09 35.4 0.1 2.2e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG46044.1 - 5.4e-08 32.8 12.0 5.4e-08 32.8 12.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 EMG46044.1 - 9 6.5 22.0 0.59 10.2 1.4 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Sugar_tr PF00083.24 EMG46045.1 - 1.6e-106 356.9 24.6 1.9e-106 356.6 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG46045.1 - 7.1e-19 67.9 48.0 5.2e-18 65.1 23.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily PQ-loop PF04193.14 EMG46046.1 - 1.5e-41 140.0 11.4 1.5e-22 79.1 1.3 2.8 2 0 0 2 2 2 2 PQ loop repeat Androgen_recep PF02166.16 EMG46046.1 - 0.025 13.4 0.3 0.034 13.0 0.3 1.1 1 0 0 1 1 1 0 Androgen receptor Zn_clus PF00172.18 EMG46047.1 - 3.9e-09 36.5 11.4 8.4e-09 35.4 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMG46047.1 - 0.025 13.6 0.2 0.067 12.2 0.2 1.8 1 1 0 1 1 1 0 Fungal specific transcription factor domain AMP-binding PF00501.28 EMG46048.1 - 3.8e-59 200.4 0.0 2e-58 198.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme RRM_1 PF00076.22 EMG46049.1 - 2e-05 24.3 0.0 1.5 8.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EMG46049.1 - 0.00084 19.2 0.1 0.0034 17.2 0.1 2.1 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain DUF5399 PF17377.2 EMG46049.1 - 0.056 13.3 6.3 0.38 10.6 1.2 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5399) Flavoprotein PF02441.19 EMG46050.1 - 5e-49 166.1 0.0 7.2e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein Macoilin PF09726.9 EMG46050.1 - 3.5 6.1 8.3 4.6 5.7 8.3 1.2 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 EMG46050.1 - 3.8 5.7 6.2 6.2 5.1 6.2 1.4 1 0 0 1 1 1 0 Menin Nop14 PF04147.12 EMG46050.1 - 3.9 5.6 26.2 7.2 4.7 26.2 1.3 1 0 0 1 1 1 0 Nop14-like family MAP65_ASE1 PF03999.12 EMG46051.1 - 1.4e-54 185.9 48.1 1.4e-54 185.9 48.1 2.9 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) ParcG PF10274.9 EMG46051.1 - 0.039 14.1 1.0 0.64 10.1 0.1 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein DUF442 PF04273.13 EMG46051.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Zn_clus PF00172.18 EMG46053.1 - 2.8e-08 33.7 11.6 7.9e-08 32.3 11.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMG46053.1 - 5.2e-08 32.2 4.7 2.2e-05 23.7 1.2 3.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain SKN1 PF03935.15 EMG46054.1 - 1.3e-235 782.5 5.1 1.5e-235 782.3 5.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) tRNA_int_end_N2 PF12928.7 EMG46055.1 - 7.1e-16 58.2 0.0 1.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EMG46055.1 - 0.065 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain SKN1 PF03935.15 EMG46057.1 - 8.8e-252 835.9 1.8 1.3e-251 835.3 1.8 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) F-box_4 PF15966.5 EMG46060.1 - 1.5e-06 28.1 0.0 4.2e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EMG46060.1 - 2.4e-06 27.4 0.1 7.4e-06 25.8 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMG46060.1 - 9.5e-05 22.2 0.6 0.00047 20.0 0.4 2.4 2 0 0 2 2 2 1 F-box domain Sec2p PF06428.11 EMG46061.1 - 2e-28 98.2 11.7 2e-28 98.2 11.7 3.2 4 0 0 4 4 4 1 GDP/GTP exchange factor Sec2p DUF724 PF05266.14 EMG46061.1 - 1.8 8.3 20.7 0.93 9.3 4.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Csm1_N PF18504.1 EMG46061.1 - 4.2 7.8 13.4 0.65 10.4 2.0 3.4 2 1 1 3 3 3 0 Csm1 N-terminal domain TSC22 PF01166.18 EMG46061.1 - 5.6 7.4 14.4 0.13 12.6 3.9 3.3 2 1 1 3 3 3 0 TSC-22/dip/bun family FA_desaturase PF00487.24 EMG46063.1 - 4.8e-23 82.3 18.8 7.6e-23 81.7 18.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EMG46063.1 - 9.2e-07 29.1 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) GTP_EFTU PF00009.27 EMG46064.1 - 2.9e-62 209.7 0.2 5.1e-62 208.9 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EMG46064.1 - 4.2e-36 123.4 0.0 1e-35 122.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EMG46064.1 - 1.7e-30 104.9 0.0 4.4e-30 103.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EMG46064.1 - 4.3e-21 74.7 0.0 1e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMG46064.1 - 5e-13 49.2 1.3 1.2e-12 48.0 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EMG46064.1 - 9.4e-06 25.5 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EMG46064.1 - 0.012 15.7 0.1 0.031 14.4 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 EMG46064.1 - 0.033 14.7 0.0 0.56 10.7 0.0 2.8 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain Ribosomal_L14e PF01929.17 EMG46065.1 - 8.1e-35 119.2 2.7 1.2e-34 118.7 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 tRNA-synt_1e PF01406.19 EMG46066.1 - 1.3e-135 451.6 5.1 1.3e-135 451.6 5.1 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EMG46066.1 - 1.8e-08 33.6 5.5 3.1e-05 22.9 0.1 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EMG46066.1 - 0.00027 19.4 0.0 0.00027 19.4 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) SPC22 PF04573.12 EMG46067.1 - 2.3e-57 193.2 1.0 2.7e-57 193.0 1.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit PPR_2 PF13041.6 EMG46068.1 - 0.0012 19.0 3.6 0.27 11.5 0.1 4.9 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.20 EMG46068.1 - 0.059 13.6 2.9 8.7 6.9 0.1 4.5 4 0 0 4 4 4 0 PPR repeat Chitin_synth_2 PF03142.15 EMG46070.1 - 2.7e-281 933.8 0.4 4.2e-281 933.1 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EMG46070.1 - 1.4e-14 54.5 0.7 4.3e-14 52.9 0.7 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMG46070.1 - 5.4e-12 46.1 0.0 6.7e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EMG46070.1 - 0.00012 21.6 0.1 0.00051 19.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EMG46070.1 - 0.002 18.0 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 DNA_pol_A_exo1 PF01612.20 EMG46072.1 - 0.0025 17.5 0.0 0.0056 16.4 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease HLH PF00010.26 EMG46073.1 - 2.9e-17 62.4 0.5 5.9e-17 61.4 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HeLo PF14479.6 EMG46073.1 - 0.0081 16.0 1.7 0.014 15.2 1.7 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation NARP1 PF12569.8 EMG46073.1 - 1.1 8.1 13.3 1.5 7.6 13.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Tmemb_9 PF05434.11 EMG46075.1 - 0.12 12.2 0.5 0.15 12.0 0.5 1.3 1 0 0 1 1 1 0 TMEM9 Dexa_ind PF15198.6 EMG46075.1 - 2.6 8.2 11.8 0.75 9.9 5.7 2.0 1 1 1 2 2 2 0 Dexamethasone-induced DUF4149 PF13664.6 EMG46076.1 - 1.2e-22 80.1 2.6 1.3e-21 76.8 0.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF2114 PF09887.9 EMG46076.1 - 0.19 10.2 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) MutS_V PF00488.21 EMG46078.1 - 4.2e-64 216.0 0.1 8.6e-64 215.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMG46078.1 - 1.8e-33 116.4 1.6 2.2e-33 116.1 0.3 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EMG46078.1 - 1.2e-31 109.3 0.0 2.7e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EMG46078.1 - 2.8e-12 47.1 0.7 8.8e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EMG46078.1 - 4.8e-10 39.7 3.3 6.6e-10 39.2 0.9 2.6 2 0 0 2 2 2 1 MutS family domain IV AAA_27 PF13514.6 EMG46078.1 - 0.035 13.7 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMG46078.1 - 0.043 13.6 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NOA36 PF06524.12 EMG46078.1 - 3.9 6.7 17.4 9.3 5.5 17.4 1.6 1 0 0 1 1 1 0 NOA36 protein NTP_transferase PF00483.23 EMG46079.1 - 5.6e-19 68.7 0.0 3.3e-12 46.5 0.0 2.7 3 0 0 3 3 3 2 Nucleotidyl transferase Hexapep PF00132.24 EMG46079.1 - 2.8e-07 30.0 17.9 0.00081 19.0 2.6 4.6 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EMG46079.1 - 0.0015 17.6 3.1 0.0039 16.2 3.1 1.8 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 EMG46079.1 - 0.0089 14.2 2.6 0.014 13.6 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 EMG46079.1 - 0.0095 16.3 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glycos_transf_2 PF00535.26 EMG46079.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Hexapep_2 PF14602.6 EMG46079.1 - 0.11 12.3 11.3 1.2 8.9 1.5 3.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase AA_permease PF00324.21 EMG46080.1 - 1.8e-106 356.6 42.8 2.2e-106 356.3 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG46080.1 - 3.9e-34 118.2 47.2 4.6e-34 118.0 47.2 1.0 1 0 0 1 1 1 1 Amino acid permease Sec7_N PF12783.7 EMG46081.1 - 4.9e-39 133.8 8.8 1e-38 132.7 5.9 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EMG46081.1 - 1.5e-07 31.2 0.6 2.6e-06 27.2 0.0 2.7 2 1 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Staygreen PF12638.7 EMG46081.1 - 0.029 14.2 0.1 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Staygreen protein DUF4112 PF13430.6 EMG46082.1 - 6.8e-28 97.0 0.3 9.5e-28 96.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2207 PF09972.9 EMG46082.1 - 0.025 13.4 0.2 0.036 12.8 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) phage_tail_N PF08400.10 EMG46082.1 - 0.046 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Prophage tail fibre N-terminal DDE_1 PF03184.19 EMG46085.1 - 1.5e-24 86.6 0.2 6.2e-20 71.6 0.0 2.9 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EMG46085.1 - 6e-06 26.2 0.5 1.6e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 EMG46085.1 - 8.3e-06 25.6 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 EMG46085.1 - 0.065 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain THDPS_N_2 PF14805.6 EMG46086.1 - 0.024 14.8 0.3 0.67 10.2 0.2 2.7 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF3657 PF12394.8 EMG46086.1 - 1.1 9.9 7.3 7.8 7.1 0.1 3.2 3 0 0 3 3 3 0 Protein FAM135 Recep_L_domain PF01030.24 EMG46087.1 - 2.8e-09 37.1 13.1 0.049 13.7 0.1 5.1 1 1 3 5 5 5 5 Receptor L domain CTP_transf_like PF01467.26 EMG46088.1 - 2.8e-05 24.3 0.0 6.1e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like SWIB PF02201.18 EMG46088.1 - 0.13 12.1 0.2 0.8 9.6 0.0 2.4 3 0 0 3 3 3 0 SWIB/MDM2 domain FKBP_C PF00254.28 EMG46089.1 - 5.1e-29 100.4 0.0 8.4e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AFT PF08731.11 EMG46090.1 - 8.4e-05 22.9 0.0 8.4e-05 22.9 0.0 4.5 4 1 1 5 5 5 1 Transcription factor AFT NAGLU_N PF12971.7 EMG46090.1 - 0.062 13.1 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain FAR1 PF03101.15 EMG46090.1 - 0.075 13.7 0.1 0.075 13.7 0.1 3.1 2 1 0 2 2 2 0 FAR1 DNA-binding domain CRAL_TRIO_2 PF13716.6 EMG46091.1 - 1.9e-15 57.2 1.5 1.9e-15 57.2 1.5 2.4 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 EMG46091.1 - 8.8e-10 38.6 0.4 3.1e-09 36.8 0.4 1.9 1 0 0 1 1 1 1 RhoGAP domain Lyase_catalyt PF09093.11 EMG46091.1 - 0.068 12.3 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Lyase, catalytic RPN1_RPN2_N PF17781.1 EMG46092.1 - 4.6e-113 377.7 3.0 1.3e-112 376.2 3.2 1.7 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 EMG46092.1 - 1.1e-26 91.9 14.8 3.6e-05 24.0 0.4 9.7 10 0 0 10 10 10 4 Proteasome/cyclosome repeat RPN1_C PF18051.1 EMG46092.1 - 3.3e-26 91.1 0.1 6.1e-26 90.2 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 EMG46092.1 - 2.9e-06 27.6 1.7 0.16 12.4 0.0 3.9 4 1 1 5 5 5 2 HEAT repeats Zip PF02535.22 EMG46092.1 - 0.0051 16.1 0.1 0.0051 16.1 0.1 1.8 2 0 0 2 2 2 1 ZIP Zinc transporter BUD22 PF09073.10 EMG46092.1 - 0.032 13.6 12.4 0.0079 15.6 4.8 2.1 2 0 0 2 2 2 0 BUD22 Utp13 PF08625.11 EMG46092.1 - 0.036 14.0 0.2 0.18 11.7 0.2 2.3 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain GTP_EFTU_D2 PF03144.25 EMG46092.1 - 0.97 9.9 3.8 1.3 9.5 0.7 2.8 3 0 0 3 3 3 0 Elongation factor Tu domain 2 Raftlin PF15250.6 EMG46092.1 - 6.3 5.4 8.2 0.62 8.8 0.3 2.6 3 0 0 3 3 3 0 Raftlin ATP-synt_C PF00137.21 EMG46093.1 - 1.5e-26 92.5 29.6 3.3e-15 56.2 11.5 2.3 2 0 0 2 2 2 2 ATP synthase subunit C DUF3671 PF12420.8 EMG46093.1 - 0.61 10.2 4.9 0.21 11.7 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function zf-H2C2_2 PF13465.6 EMG46094.1 - 0.0001 22.6 5.1 0.015 15.7 1.3 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EMG46094.1 - 0.00088 19.6 2.4 0.00088 19.6 2.4 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG46094.1 - 0.0012 19.5 15.8 0.0014 19.3 2.2 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger TFIIA PF03153.13 EMG46094.1 - 0.035 14.1 8.6 0.057 13.4 8.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_5 PF13909.6 EMG46094.1 - 0.089 12.6 7.4 0.43 10.4 7.4 2.3 1 1 0 1 1 1 0 C2H2-type zinc-finger domain zinc_ribbon_5 PF13719.6 EMG46094.1 - 0.097 12.5 0.6 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.12 EMG46094.1 - 0.17 12.2 9.8 0.066 13.5 3.6 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 EMG46094.1 - 0.36 10.6 1.9 11 5.9 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type GN3L_Grn1 PF08701.11 EMG46094.1 - 0.84 9.8 8.8 2 8.6 8.8 1.6 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Spermine_synth PF01564.17 EMG46095.1 - 3.7e-58 196.0 0.3 6.4e-58 195.3 0.3 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EMG46095.1 - 7e-22 77.1 0.4 1.3e-21 76.2 0.4 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain DUF43 PF01861.16 EMG46095.1 - 0.045 13.0 0.2 0.088 12.0 0.2 1.4 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Pyr_redox_2 PF07992.14 EMG46095.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EMG46095.1 - 0.19 12.2 0.0 0.62 10.5 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF261 PF03196.13 EMG46096.1 - 0.91 9.6 14.2 3.4 7.8 0.4 3.6 2 1 1 4 4 4 0 Protein of unknown function, DUF261 Bud13 PF09736.9 EMG46097.1 - 1.7e-19 70.6 13.0 1.7e-19 70.6 13.0 3.2 2 2 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex PDCD9 PF07147.12 EMG46097.1 - 0.028 13.7 2.9 0.057 12.6 2.4 1.6 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) TPR_2 PF07719.17 EMG46098.1 - 3.2e-07 30.0 0.7 0.013 15.5 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMG46098.1 - 4e-07 29.7 0.4 0.12 12.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMG46098.1 - 3.6e-06 26.6 4.4 0.016 14.8 0.0 4.4 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.6 EMG46098.1 - 7.9e-06 26.3 4.7 0.57 10.7 0.1 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG46098.1 - 1.9e-05 24.8 0.6 0.063 13.5 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EMG46098.1 - 5.3e-05 22.9 1.4 0.0069 16.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMG46098.1 - 0.00016 22.2 0.0 0.026 15.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMG46098.1 - 0.00021 21.5 0.7 3.5 8.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMG46098.1 - 0.00023 21.7 0.1 0.42 11.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF4800 PF16057.5 EMG46098.1 - 0.044 13.0 0.1 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) TPR_MalT PF17874.1 EMG46098.1 - 0.064 12.6 1.5 5.8 6.2 0.0 2.9 3 1 1 4 4 4 0 MalT-like TPR region XRN_N PF03159.18 EMG46100.1 - 2.4e-95 318.6 0.2 2.4e-95 318.6 0.2 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EMG46100.1 - 2.8e-78 263.9 24.5 6.2e-60 203.4 1.9 3.8 3 1 0 3 3 3 3 Xrn1 helical domain XRN1_D1 PF18332.1 EMG46100.1 - 4.2e-61 206.1 0.1 4.2e-61 206.1 0.1 3.1 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D1 domain Xrn1_D3 PF18194.1 EMG46100.1 - 6.7e-34 115.8 0.6 2.2e-33 114.2 0.6 2.0 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 XRN1_D2_D3 PF18334.1 EMG46100.1 - 2.4e-28 98.2 0.1 1e-27 96.1 0.1 2.2 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EMG46100.1 - 3.7e-14 52.6 0.1 7.1e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Glutaredoxin PF00462.24 EMG46101.1 - 0.017 15.3 0.7 0.069 13.4 0.1 2.2 2 0 0 2 2 2 0 Glutaredoxin IL17R_fnIII_D1 PF16556.5 EMG46101.1 - 0.034 13.8 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Interleukin-17 receptor, fibronectin-III-like domain 1 CHCH PF06747.13 EMG46102.1 - 0.00092 19.3 4.7 0.0013 18.8 4.7 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 EMG46102.1 - 0.0093 16.0 1.2 0.013 15.5 1.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 EMG46102.1 - 0.024 15.0 4.2 0.25 11.7 0.5 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 EMG46102.1 - 0.1 12.9 4.3 0.41 11.0 4.3 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EMG46102.1 - 0.71 9.9 4.2 1.2 9.2 4.2 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Mito_carr PF00153.27 EMG46103.1 - 5.5e-74 244.2 1.2 1.5e-25 89.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 EMG46103.1 - 0.00049 19.8 2.1 52 4.2 0.0 6.3 6 0 0 6 6 6 0 EF-hand domain EF-hand_1 PF00036.32 EMG46103.1 - 0.028 14.0 2.4 20 5.0 0.0 4.9 5 0 0 5 5 5 0 EF hand YebF PF13995.6 EMG46103.1 - 0.043 13.8 0.0 0.043 13.8 0.0 2.4 4 0 0 4 4 4 0 YebF-like protein DUF3686 PF12458.8 EMG46103.1 - 0.09 11.3 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 ATPase involved in DNA repair Upf2 PF04050.14 EMG46104.1 - 4.2 8.1 10.6 0.23 12.2 0.7 2.5 1 1 1 2 2 2 0 Up-frameshift suppressor 2 zf-C2H2 PF00096.26 EMG46105.1 - 2e-10 40.6 19.7 0.00023 21.4 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMG46105.1 - 8.2e-10 38.7 13.9 4.4e-08 33.2 1.5 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMG46105.1 - 1e-07 32.2 16.7 0.022 15.6 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMG46105.1 - 3.6e-05 23.6 3.8 0.18 11.8 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EMG46105.1 - 0.0075 16.1 0.9 0.0075 16.1 0.9 1.8 2 0 0 2 2 1 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 EMG46105.1 - 0.036 14.4 7.9 4.6 7.6 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-RRPl_C4 PF17026.5 EMG46105.1 - 0.061 13.4 2.3 0.12 12.4 2.3 1.5 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-met PF12874.7 EMG46105.1 - 0.23 11.9 8.4 3 8.4 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 EMG46105.1 - 0.41 10.8 4.6 2.5 8.3 0.4 2.5 1 1 2 3 3 3 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 EMG46105.1 - 0.44 11.2 10.5 9.3 6.9 0.4 3.5 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats C1_4 PF07975.12 EMG46105.1 - 0.94 9.8 6.4 12 6.2 1.4 2.6 1 1 0 2 2 2 0 TFIIH C1-like domain Endonuclease_7 PF02945.15 EMG46105.1 - 1.1 9.2 5.8 0.4 10.6 2.4 2.0 1 1 1 2 2 2 0 Recombination endonuclease VII zf_C2H2_ZHX PF18387.1 EMG46105.1 - 1.2 8.9 7.6 5.9 6.6 0.2 2.9 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_UBZ PF18439.1 EMG46105.1 - 1.3 8.7 6.7 4.9 6.8 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 EMG46105.1 - 2 8.5 5.6 30 4.7 5.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon Zn_ribbon_SprT PF17283.2 EMG46105.1 - 2.2 8.2 7.6 5.5 7.0 0.1 2.5 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Glutaredoxin PF00462.24 EMG46106.1 - 0.027 14.7 0.2 0.088 13.0 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin IL17R_fnIII_D1 PF16556.5 EMG46106.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Interleukin-17 receptor, fibronectin-III-like domain 1 Pkinase PF00069.25 EMG46108.1 - 4.9e-48 163.8 0.1 1.8e-47 161.9 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG46108.1 - 6.4e-19 68.2 0.0 2e-18 66.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EMG46108.1 - 0.067 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 RIO1 family NOA36 PF06524.12 EMG46108.1 - 9.3 5.5 6.4 16 4.7 6.4 1.3 1 0 0 1 1 1 0 NOA36 protein HSP70 PF00012.20 EMG46109.1 - 3.2e-52 177.6 0.1 3.5e-52 177.4 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 EMG46109.1 - 8.5e-05 22.4 0.0 9.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1464 PF07318.12 EMG46109.1 - 0.0031 16.7 0.0 0.0036 16.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1464) MreB_Mbl PF06723.13 EMG46109.1 - 0.0089 14.9 0.0 0.011 14.6 0.0 1.0 1 0 0 1 1 1 1 MreB/Mbl protein Nucleoporin_FG PF13634.6 EMG46110.1 - 1.5e-29 102.6 132.5 4e-13 50.0 32.9 4.0 1 1 1 3 3 3 3 Nucleoporin FG repeat region Med13_C PF06333.12 EMG46110.1 - 0.57 9.4 5.5 0.71 9.1 5.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain MBOAT PF03062.19 EMG46111.1 - 2.9e-62 211.0 25.7 4.4e-62 210.5 25.7 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Abhydro_lipase PF04083.16 EMG46113.1 - 1.9e-15 56.2 0.9 4e-15 55.1 0.9 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EMG46113.1 - 1.4e-14 54.4 0.1 1.8e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 EMG46113.1 - 2.3e-05 24.2 0.1 0.072 12.7 0.0 2.7 3 1 0 3 3 3 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EMG46113.1 - 0.0039 16.5 0.0 0.099 11.9 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EMG46113.1 - 0.0045 16.8 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase UPF0565 PF10561.9 EMG46113.1 - 0.013 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Na_Ca_ex PF01699.24 EMG46114.1 - 1.2e-39 135.7 40.6 1.4e-23 83.6 16.2 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein BofC_C PF08955.10 EMG46114.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 BofC C-terminal domain HSP70 PF00012.20 EMG46115.1 - 2.6e-11 42.4 5.9 2.9e-11 42.3 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein Cnd1_N PF12922.7 EMG46115.1 - 0.018 14.9 2.2 0.023 14.6 2.2 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term TcpS PF17456.2 EMG46115.1 - 0.11 12.6 0.8 0.13 12.3 0.8 1.1 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S PUF PF00806.19 EMG46116.1 - 5.2e-49 161.3 33.6 2.5e-07 30.0 0.3 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF5439 PF17507.2 EMG46116.1 - 0.063 13.5 0.9 0.36 11.1 0.9 2.4 1 0 0 1 1 1 0 Family of unknown function (DUF5439) FAM76 PF16046.5 EMG46117.1 - 0.011 15.1 3.2 0.011 15.1 3.2 2.2 2 0 0 2 2 2 0 FAM76 protein Tropomyosin_1 PF12718.7 EMG46117.1 - 0.026 14.7 6.7 0.026 14.7 6.7 2.2 2 0 0 2 2 2 0 Tropomyosin like XLF PF09302.11 EMG46117.1 - 0.062 13.5 3.1 0.18 11.9 3.1 1.8 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component SlyX PF04102.12 EMG46117.1 - 0.53 10.9 4.8 1.8 9.3 1.8 2.8 2 0 0 2 2 2 0 SlyX DUF641 PF04859.12 EMG46117.1 - 2.6 8.4 9.1 0.91 9.9 5.2 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CDC37_N PF03234.14 EMG46117.1 - 3.2 8.7 11.2 1.1 10.1 5.3 2.8 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding AMPKBI PF04739.15 EMG46118.1 - 1.8e-26 92.2 10.4 1.8e-26 92.2 10.4 3.1 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 EMG46118.1 - 2.1e-17 63.1 0.1 4.4e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AAA PF00004.29 EMG46120.1 - 1.6e-53 180.7 0.0 1.5e-37 129.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMG46120.1 - 8.9e-12 45.4 0.7 0.00013 22.2 0.0 4.3 2 2 1 4 4 4 2 AAA domain AAA_lid_3 PF17862.1 EMG46120.1 - 3.1e-10 39.7 0.0 6.2e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 EMG46120.1 - 1.9e-09 37.2 0.1 0.00039 19.7 0.0 2.6 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_16 PF13191.6 EMG46120.1 - 1.9e-09 38.1 0.5 0.00053 20.4 0.1 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EMG46120.1 - 2.3e-09 37.4 0.0 0.00011 22.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMG46120.1 - 1.6e-08 34.5 0.1 0.00031 20.5 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EMG46120.1 - 1.9e-08 34.9 0.0 0.0031 18.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EMG46120.1 - 4.8e-08 33.0 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EMG46120.1 - 1.4e-07 31.8 0.0 8.6e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EMG46120.1 - 2.5e-07 30.3 0.2 0.0024 17.3 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_N PF02359.18 EMG46120.1 - 3.7e-06 27.0 0.0 1.3e-05 25.3 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RNA_helicase PF00910.22 EMG46120.1 - 5.3e-06 26.8 0.0 0.079 13.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 EMG46120.1 - 6.5e-06 26.0 0.0 0.052 13.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 EMG46120.1 - 7.1e-06 26.2 0.0 0.067 13.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EMG46120.1 - 1.8e-05 24.3 0.0 0.058 12.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_3 PF07726.11 EMG46120.1 - 8.4e-05 22.4 0.0 0.087 12.7 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EMG46120.1 - 8.6e-05 22.0 0.1 1.5 8.2 0.0 4.0 4 0 0 4 4 4 2 Bacterial TniB protein CDC48_2 PF02933.17 EMG46120.1 - 0.00022 20.9 0.6 0.0037 17.0 0.1 2.8 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 ABC_tran PF00005.27 EMG46120.1 - 0.00025 21.6 0.0 0.015 15.8 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Rad17 PF03215.15 EMG46120.1 - 0.00029 20.8 0.2 0.06 13.3 0.1 2.9 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 EMG46120.1 - 0.00035 20.9 0.0 0.3 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMG46120.1 - 0.00038 20.1 4.1 0.15 11.6 0.1 3.6 3 1 0 4 4 4 1 AAA domain AAA_17 PF13207.6 EMG46120.1 - 0.0011 19.4 0.0 1.1 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EMG46120.1 - 0.0018 18.0 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 EMG46120.1 - 0.0021 18.1 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EMG46120.1 - 0.0023 17.9 0.3 0.5 10.3 0.0 3.2 2 2 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EMG46120.1 - 0.0053 16.6 0.0 0.78 9.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EMG46120.1 - 0.0058 17.0 0.1 2.4 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EMG46120.1 - 0.006 16.5 1.0 3.7 7.4 0.0 3.2 4 0 0 4 4 3 1 NACHT domain ATPase_2 PF01637.18 EMG46120.1 - 0.0069 16.3 1.7 1.1 9.2 0.0 3.6 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 EMG46120.1 - 0.0093 15.1 0.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 PhoH PF02562.16 EMG46120.1 - 0.0099 15.3 0.0 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 EMG46120.1 - 0.013 14.7 0.0 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 EMG46120.1 - 0.015 14.6 0.1 0.48 9.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EMG46120.1 - 0.017 14.5 0.1 5.8 6.2 0.0 2.9 3 0 0 3 3 3 0 KaiC SRP54 PF00448.22 EMG46120.1 - 0.018 14.6 0.0 3 7.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EMG46120.1 - 0.024 14.3 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EMG46120.1 - 0.025 14.5 0.9 3.6 7.5 0.0 2.9 3 0 0 3 3 2 0 NTPase Vps4_C PF09336.10 EMG46120.1 - 0.027 14.5 0.0 0.081 12.9 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.6 EMG46120.1 - 0.028 14.6 0.0 3.4 7.8 0.0 3.0 2 1 0 3 3 3 0 Sigma-54 interaction domain KTI12 PF08433.10 EMG46120.1 - 0.036 13.5 0.0 0.95 8.9 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Herpes_UL74 PF07982.12 EMG46120.1 - 0.04 12.9 0.1 0.067 12.1 0.1 1.2 1 0 0 1 1 1 0 Herpes UL74 glycoproteins IPT PF01745.16 EMG46120.1 - 0.056 12.8 0.0 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase ATP-synt_ab PF00006.25 EMG46120.1 - 0.096 12.3 0.0 13 5.3 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PPV_E1_C PF00519.17 EMG46120.1 - 0.12 11.2 0.1 0.4 9.5 0.0 1.7 2 0 0 2 2 2 0 Papillomavirus helicase Actin PF00022.19 EMG46121.1 - 2.2e-143 477.8 0.0 7.1e-143 476.1 0.0 1.7 1 1 0 1 1 1 1 Actin OPT PF03169.15 EMG46122.1 - 1.5e-156 522.6 36.3 1.8e-156 522.4 36.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PTPLA PF04387.14 EMG46122.1 - 0.065 13.0 3.6 1.1 8.9 1.1 2.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase-like protein, PTPLA Fungal_trans PF04082.18 EMG46123.1 - 4.5e-10 39.0 0.1 4.5e-10 39.0 0.1 3.2 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG46123.1 - 1e-07 32.0 14.1 2.5e-07 30.7 14.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EMG46123.1 - 0.0021 18.1 40.7 0.0021 18.1 40.7 3.1 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit NTPase_1 PF03266.15 EMG46123.1 - 0.11 12.4 0.2 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 NTPase Synaptobrevin PF00957.21 EMG46124.1 - 3.7e-32 110.0 1.4 4.2e-32 109.8 1.4 1.0 1 0 0 1 1 1 1 Synaptobrevin SNARE PF05739.19 EMG46124.1 - 0.3 11.1 8.9 4.7 7.3 7.3 2.5 2 0 0 2 2 2 0 SNARE domain GCV_H PF01597.19 EMG46125.1 - 1.9e-39 134.3 0.3 2.4e-39 134.0 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EMG46125.1 - 0.00041 20.1 0.1 0.0044 16.8 0.1 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 EMG46125.1 - 0.002 18.0 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain MCR_alpha PF02249.17 EMG46125.1 - 0.12 12.8 1.3 0.81 10.1 0.0 2.1 1 1 1 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain PTS_EIIA_1 PF00358.20 EMG46125.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 FAD_binding_2 PF00890.24 EMG46126.1 - 5.2e-84 282.7 0.0 6.3e-84 282.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EMG46126.1 - 5.4e-22 77.7 0.2 1e-20 73.7 0.0 2.9 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EMG46126.1 - 6.8e-12 45.6 0.1 1.4e-11 44.6 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EMG46126.1 - 1.1e-06 28.3 0.1 2.6e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMG46126.1 - 2e-05 24.7 1.5 7.1e-05 23.0 0.6 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMG46126.1 - 3.4e-05 23.2 0.8 0.00026 20.3 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMG46126.1 - 0.0015 17.4 2.1 0.025 13.3 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EMG46126.1 - 0.0031 16.8 0.5 0.0075 15.6 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EMG46126.1 - 0.0067 15.7 0.3 0.01 15.1 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EMG46126.1 - 0.023 13.8 0.9 0.023 13.8 0.9 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMG46126.1 - 0.16 11.2 0.6 1.7 7.8 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PNK3P PF08645.11 EMG46126.1 - 0.16 11.7 0.0 0.7 9.6 0.0 2.0 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Thi4 PF01946.17 EMG46126.1 - 0.44 9.7 2.4 10 5.2 0.3 2.8 3 0 0 3 3 3 0 Thi4 family SNF2_N PF00176.23 EMG46127.1 - 2e-57 194.5 0.0 3.3e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EMG46127.1 - 3.5e-49 167.4 1.6 5.9e-49 166.7 1.6 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 EMG46127.1 - 1.1e-16 61.2 0.0 2.2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG46127.1 - 1.2e-06 28.6 0.0 3.5e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EMG46127.1 - 2.1e-05 23.8 0.4 9.8e-05 21.7 0.1 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 EMG46127.1 - 0.0091 16.3 0.1 0.17 12.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain Ran-binding PF05508.11 EMG46128.1 - 6.7e-101 337.4 1.9 6.7e-101 337.4 1.9 1.5 2 0 0 2 2 2 1 RanGTP-binding protein PBP1_TM PF14812.6 EMG46128.1 - 0.00027 21.3 6.7 0.0016 18.8 3.2 2.6 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 EMG46128.1 - 0.24 11.6 6.1 0.74 10.1 6.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) GCIP PF13324.6 EMG46128.1 - 0.67 9.5 6.1 0.71 9.4 1.6 2.4 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 EMG46128.1 - 6.4 6.0 6.3 11 5.3 6.3 1.3 1 0 0 1 1 1 0 NOA36 protein Copper-fist PF00649.18 EMG46129.1 - 6.3e-20 70.4 1.3 6.3e-20 70.4 1.3 2.3 1 1 1 2 2 2 1 Copper fist DNA binding domain VESA1_N PF12785.7 EMG46129.1 - 7.7 5.4 17.4 12 4.7 17.4 1.3 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 FMN_dh PF01070.18 EMG46130.1 - 8.4e-114 380.2 0.0 1e-113 379.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EMG46130.1 - 1.4e-26 92.5 0.3 4e-26 90.9 0.2 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EMG46130.1 - 1.9e-06 27.3 0.0 3.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EMG46130.1 - 0.0007 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMG46130.1 - 0.043 13.2 0.1 0.088 12.2 0.1 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase HicA_toxin PF07927.12 EMG46130.1 - 0.062 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, KCT2 PF17818.1 EMG46130.1 - 0.44 10.7 4.1 0.86 9.7 4.1 1.4 1 0 0 1 1 1 0 Keratinocyte-associated gene product OPT PF03169.15 EMG46131.1 - 4.1e-158 527.8 37.7 4.7e-158 527.6 37.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CPSF100_C PF13299.6 EMG46132.1 - 0.0019 18.4 2.1 0.0019 18.4 2.1 1.1 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Atrophin-1 PF03154.15 EMG46132.1 - 0.0034 15.8 5.0 0.0036 15.7 5.0 1.1 1 0 0 1 1 1 1 Atrophin-1 family Phage_Gp23 PF10669.9 EMG46132.1 - 0.0061 16.9 4.3 0.0078 16.5 4.3 1.2 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) Connexin PF00029.19 EMG46132.1 - 0.007 16.2 2.7 0.008 16.0 2.7 1.1 1 0 0 1 1 1 1 Connexin PTPRCAP PF15713.5 EMG46132.1 - 0.0094 16.2 6.7 0.011 16.0 6.7 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated CBP_BcsG PF11658.8 EMG46132.1 - 0.012 14.1 1.1 0.013 13.9 1.1 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG OATP PF03137.20 EMG46132.1 - 0.021 13.2 0.8 0.023 13.0 0.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.15 EMG46132.1 - 0.024 13.6 1.2 0.026 13.5 1.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4820 PF16091.5 EMG46132.1 - 0.027 13.8 3.9 0.029 13.7 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) BIRC6 PF12356.8 EMG46132.1 - 0.028 13.9 2.7 0.025 14.0 1.9 1.3 1 1 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 O-antigen_lig PF13425.6 EMG46132.1 - 0.032 13.0 1.9 0.034 13.0 1.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FAM176 PF14851.6 EMG46132.1 - 0.033 13.9 8.5 0.04 13.6 8.5 1.1 1 0 0 1 1 1 0 FAM176 family DUF2514 PF10721.9 EMG46132.1 - 0.049 13.7 0.4 0.049 13.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) V_ATPase_I PF01496.19 EMG46132.1 - 0.052 11.5 4.6 0.054 11.4 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family dsRBD2 PF17842.1 EMG46132.1 - 0.055 13.7 2.9 0.06 13.5 2.9 1.1 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 DDHD PF02862.17 EMG46132.1 - 0.064 13.4 2.3 0.064 13.4 2.3 1.1 1 0 0 1 1 1 0 DDHD domain CLN3 PF02487.17 EMG46132.1 - 0.071 12.1 1.7 0.072 12.1 1.7 1.0 1 0 0 1 1 1 0 CLN3 protein RabGAP-TBC PF00566.18 EMG46132.1 - 0.092 12.4 2.9 0.098 12.3 2.9 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain FHIPEP PF00771.20 EMG46132.1 - 0.11 10.9 1.0 0.11 11.0 1.0 1.0 1 0 0 1 1 1 0 FHIPEP family SID-1_RNA_chan PF13965.6 EMG46132.1 - 0.12 10.8 1.5 0.13 10.7 1.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PEX11 PF05648.14 EMG46132.1 - 0.13 11.7 1.3 0.14 11.6 1.3 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) CSG2 PF16965.5 EMG46132.1 - 0.14 11.1 2.1 0.15 11.0 2.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Zip PF02535.22 EMG46132.1 - 0.15 11.2 2.8 0.15 11.2 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.13 EMG46132.1 - 0.16 10.8 7.0 0.18 10.5 7.0 1.0 1 0 0 1 1 1 0 Otopetrin TRAP_alpha PF03896.16 EMG46132.1 - 0.23 10.6 6.6 0.25 10.5 6.6 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Kei1 PF08552.11 EMG46132.1 - 0.36 10.7 2.6 0.43 10.4 2.6 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Folate_carrier PF01770.18 EMG46132.1 - 0.39 9.4 1.8 0.4 9.4 1.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier MAP17 PF15807.5 EMG46132.1 - 0.39 11.0 8.2 0.45 10.8 8.2 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Mem_trans PF03547.18 EMG46132.1 - 0.46 8.8 3.9 0.54 8.6 3.9 1.0 1 0 0 1 1 1 0 Membrane transport protein Nucleoside_tran PF01733.18 EMG46132.1 - 0.47 9.8 1.1 0.49 9.7 1.1 1.1 1 0 0 1 1 1 0 Nucleoside transporter Trypan_PARP PF05887.11 EMG46132.1 - 0.71 9.9 10.4 0.87 9.6 10.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_Ag35 PF03286.14 EMG46132.1 - 0.72 9.6 15.8 0.84 9.4 15.8 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFB6 PF17110.5 EMG46132.1 - 0.73 9.6 7.4 0.94 9.2 7.4 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 EMG46132.1 - 0.73 8.1 9.4 0.82 7.9 9.4 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EMG46132.1 - 1.2 8.8 14.2 1.5 8.6 14.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.10 EMG46132.1 - 1.3 9.1 7.3 1.5 8.8 7.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ureide_permease PF07168.11 EMG46132.1 - 1.3 7.7 4.7 1.4 7.6 4.7 1.0 1 0 0 1 1 1 0 Ureide permease Conotoxin PF02950.17 EMG46132.1 - 1.3 10.0 5.1 1.6 9.8 4.1 1.7 1 1 0 1 1 1 0 Conotoxin AIF_C PF14721.6 EMG46132.1 - 1.7 9.0 9.5 2.1 8.7 9.5 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Tim54 PF11711.8 EMG46132.1 - 1.9 7.2 12.9 2.2 7.0 12.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 EMG46132.1 - 2.4 8.6 9.7 2.8 8.4 9.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3530 PF12048.8 EMG46132.1 - 2.7 7.3 9.0 3.2 7.1 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Paramyxo_ncap PF00973.19 EMG46132.1 - 4.3 6.1 9.4 5.1 5.9 9.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3915 PF13054.6 EMG46132.1 - 5.6 7.0 10.5 8.6 6.4 10.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) eIF_4EBP PF05456.11 EMG46132.1 - 6.1 6.8 7.6 8.5 6.3 7.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) EIIBC-GUT_N PF03612.14 EMG46132.1 - 6.2 6.5 9.2 7.5 6.3 9.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PPL5 PF18168.1 EMG46132.1 - 7.4 5.8 9.9 8.5 5.6 9.9 1.0 1 0 0 1 1 1 0 Prim-pol family 5 RrnaAD PF00398.20 EMG46133.1 - 4.6e-70 235.7 0.1 5.6e-70 235.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EMG46133.1 - 4.4e-07 30.5 0.0 1.4e-06 28.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG46133.1 - 4.2e-05 24.1 0.0 0.0001 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMG46133.1 - 0.00034 20.4 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EMG46133.1 - 0.00097 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EMG46133.1 - 0.0077 17.0 0.0 0.017 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EMG46133.1 - 0.0083 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 EMG46133.1 - 0.019 14.8 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 EMG46133.1 - 0.036 13.7 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AAA_lid_4 PF17864.1 EMG46133.1 - 0.053 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 RuvB AAA lid domain MTS PF05175.14 EMG46133.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EMG46133.1 - 0.11 12.4 0.0 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.12 EMG46133.1 - 0.12 11.4 0.0 0.27 10.3 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase PRMT5 PF05185.16 EMG46133.1 - 0.13 12.1 0.1 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Kelch_4 PF13418.6 EMG46134.1 - 8.8e-40 134.5 5.6 7.6e-08 32.2 0.0 6.9 5 3 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EMG46134.1 - 1.3e-32 111.4 2.1 1.1e-10 41.5 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain DUF4110 PF13422.6 EMG46134.1 - 1.2e-24 86.2 2.8 1.5e-24 85.8 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 EMG46134.1 - 4e-22 77.7 7.2 0.00068 19.8 0.0 6.2 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EMG46134.1 - 7.5e-22 76.9 6.2 0.00021 21.2 0.0 6.2 6 1 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EMG46134.1 - 7.1e-14 51.1 9.5 0.00012 21.6 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EMG46134.1 - 7.8e-10 38.3 14.3 0.16 12.0 0.0 6.6 6 1 0 6 6 6 4 Kelch motif Gal4_dimer PF03902.13 EMG46134.1 - 7.7 6.8 7.2 3.8 7.7 2.6 2.5 2 0 0 2 2 2 0 Gal4-like dimerisation domain SH3_1 PF00018.28 EMG46135.1 - 6.8e-26 89.6 8.5 3.5e-13 48.9 1.3 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EMG46135.1 - 5.5e-25 87.0 4.9 2.3e-12 46.6 0.6 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 EMG46135.1 - 3.8e-20 71.9 0.0 7.4e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 EMG46135.1 - 7e-13 48.0 0.6 8.6e-06 25.3 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain FOG_N PF15888.5 EMG46135.1 - 1.6 9.1 6.2 19 5.6 0.0 3.4 3 1 1 4 4 4 0 Folded gastrulation N-terminus SPRY PF00622.28 EMG46136.1 - 3.2e-13 49.8 0.0 5.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DPBB_1 PF03330.18 EMG46137.1 - 2.4e-08 34.1 0.0 5.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EMG46137.1 - 0.014 15.2 0.2 0.029 14.2 0.2 1.5 1 0 0 1 1 1 0 Barwin family DUF2076 PF09849.9 EMG46137.1 - 0.054 13.5 4.6 0.035 14.2 3.2 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cerato-platanin PF07249.12 EMG46137.1 - 0.054 13.6 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Cerato-platanin PIN_4 PF13638.6 EMG46138.1 - 2.2e-17 63.6 0.1 2.2e-17 63.6 0.1 3.2 3 0 0 3 3 3 1 PIN domain TFIIA PF03153.13 EMG46138.1 - 1.3 8.9 53.0 0.79 9.7 43.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit tRNA-synt_1b PF00579.25 EMG46139.1 - 7.5e-72 242.1 0.0 8.8e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.20 EMG46140.1 - 2.3e-16 59.7 14.1 2.3e-16 59.7 14.1 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EMG46140.1 - 1.5e-08 34.3 0.0 3.8e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-CpG_bind_C PF12269.8 EMG46140.1 - 0.00087 19.1 2.9 0.00087 19.1 2.9 2.9 3 0 0 3 3 3 1 CpG binding protein zinc finger C terminal domain zf-RING_5 PF14634.6 EMG46140.1 - 0.00097 19.1 0.3 0.00097 19.1 0.3 3.0 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EMG46140.1 - 0.0011 19.2 1.0 0.0011 19.2 1.0 3.3 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 EMG46140.1 - 0.0022 17.8 0.6 0.0022 17.8 0.6 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) U1snRNP70_N PF12220.8 EMG46140.1 - 0.019 15.6 4.5 7 7.4 3.1 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-RING_UBOX PF13445.6 EMG46140.1 - 0.023 14.7 0.2 0.023 14.7 0.2 2.9 2 0 0 2 2 2 0 RING-type zinc-finger Sgf11 PF08209.11 EMG46140.1 - 0.04 13.5 2.0 0.072 12.7 0.7 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C3HC4_2 PF13923.6 EMG46140.1 - 1.6 8.7 7.9 0.063 13.1 0.8 2.5 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMG46140.1 - 5.7 7.3 7.5 0.16 12.3 0.3 2.2 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-UBR PF02207.20 EMG46141.1 - 2.6e-16 59.5 10.0 2.6e-16 59.5 10.0 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-C3HC4 PF00097.25 EMG46141.1 - 0.013 15.4 0.9 0.013 15.4 0.9 3.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMG46141.1 - 0.024 14.9 0.4 0.024 14.9 0.4 4.3 5 0 0 5 5 5 0 Ring finger domain ClpS PF02617.17 EMG46141.1 - 0.1 12.4 0.1 0.3 10.9 0.1 1.9 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Mannosyl_trans3 PF11051.8 EMG46142.1 - 1.3e-73 247.7 0.0 2.2e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative KH_dom-like PF14714.6 EMG46142.1 - 0.12 12.7 0.5 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal UPF0051 PF01458.17 EMG46142.1 - 0.16 11.6 0.1 0.66 9.6 0.0 1.9 2 1 1 3 3 3 0 Uncharacterized protein family (UPF0051) Hyphal_reg_CWP PF11765.8 EMG46143.1 - 5.9e-59 199.6 5.7 6.5e-59 199.5 5.7 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyd_WA PF06462.12 EMG46143.1 - 0.096 12.7 0.1 0.68 10.0 0.0 2.4 3 0 0 3 3 3 0 Propeller LRR_8 PF13855.6 EMG46144.1 - 3.6e-14 52.3 38.4 1.7e-07 30.9 1.2 7.3 5 3 2 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 EMG46144.1 - 1.3e-09 38.2 51.5 3.4e-06 27.3 1.1 9.7 7 1 4 11 11 11 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EMG46144.1 - 0.026 15.0 33.9 0.033 14.7 0.0 10.3 9 3 1 10 10 10 0 Leucine Rich Repeat LRR_6 PF13516.6 EMG46144.1 - 0.34 11.1 33.1 0.37 11.0 0.2 8.1 9 0 0 9 9 9 0 Leucine Rich repeat FNIP PF05725.12 EMG46144.1 - 0.83 9.9 29.0 14 5.9 0.8 8.4 6 4 1 7 7 7 0 FNIP Repeat OB_NTP_bind PF07717.16 EMG46146.1 - 8.5e-24 83.7 0.0 3.3e-23 81.9 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EMG46146.1 - 8.3e-21 74.3 0.1 2.2e-20 72.9 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMG46146.1 - 2.3e-12 47.2 0.0 6.5e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMG46146.1 - 4.6e-09 36.3 0.0 9.8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMG46146.1 - 4.6e-05 23.7 0.0 0.00016 22.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EMG46146.1 - 0.00014 21.6 0.1 0.0007 19.3 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EMG46146.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMG46146.1 - 0.015 15.7 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EMG46146.1 - 0.041 14.4 0.1 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 EMG46146.1 - 0.043 13.8 0.1 0.08 12.9 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2075 PF09848.9 EMG46146.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Vac14_Fab1_bd PF12755.7 EMG46147.1 - 0.0049 17.4 11.7 0.24 12.0 0.1 4.9 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region DCB PF16213.5 EMG46147.1 - 0.031 13.9 0.6 0.85 9.3 0.0 3.0 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 Ribosomal_L30 PF00327.20 EMG46148.1 - 1.1e-15 57.2 0.5 4.2e-15 55.4 0.5 2.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sulfatase PF00884.23 EMG46149.1 - 2.6e-65 220.8 0.0 3.8e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EMG46149.1 - 0.00059 18.6 0.0 0.00094 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 EMG46149.1 - 0.014 16.1 0.1 0.85 10.4 0.1 2.5 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Metalloenzyme PF01676.18 EMG46149.1 - 0.033 13.5 0.1 2.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Metalloenzyme superfamily CorA PF01544.18 EMG46150.1 - 1.6e-42 145.8 2.1 1.7e-26 93.2 0.1 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF2183 PF09949.9 EMG46151.1 - 1.8e-30 105.2 0.1 7.3e-30 103.2 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EMG46151.1 - 0.0025 17.3 0.2 0.0056 16.2 0.1 1.7 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Peptidase_M16_C PF05193.21 EMG46151.1 - 0.019 15.0 0.4 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase M16 inactive domain DUF4024 PF13216.6 EMG46151.1 - 2.9 7.9 4.7 14 5.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4024) DUF5470 PF17564.2 EMG46151.1 - 4.8 7.5 6.1 5.6 7.2 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5470) DFRP_C PF16543.5 EMG46152.1 - 5.7e-23 81.2 9.5 5.7e-23 81.2 9.5 4.0 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf_CCCH_4 PF18345.1 EMG46152.1 - 3.3e-06 26.9 5.0 3.3e-06 26.9 5.0 3.2 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 EMG46152.1 - 3.3e-05 23.6 11.0 7.2e-05 22.5 2.7 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 EMG46152.1 - 0.00027 21.6 22.5 0.00036 21.2 7.2 4.2 2 2 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 EMG46152.1 - 0.00067 19.5 3.9 0.00067 19.5 3.9 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EMG46152.1 - 0.00085 19.5 1.0 0.1 12.8 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EMG46152.1 - 3.4 8.3 13.8 0.79 10.3 4.4 2.7 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Arf PF00025.21 EMG46153.1 - 1.4e-68 229.8 0.1 1.5e-68 229.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMG46153.1 - 1.1e-15 57.9 0.0 1.5e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EMG46153.1 - 1.2e-13 51.0 1.9 8.1e-09 35.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EMG46153.1 - 2.5e-13 49.9 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EMG46153.1 - 1.4e-11 44.2 0.0 1.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EMG46153.1 - 2.1e-09 37.1 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMG46153.1 - 2.1e-05 24.6 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EMG46153.1 - 0.0052 16.1 0.1 0.0074 15.6 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MobB PF03205.14 EMG46153.1 - 0.029 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4871 PF16167.5 EMG46153.1 - 0.068 13.2 0.1 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4871) FeoB_N PF02421.18 EMG46153.1 - 0.18 11.4 0.6 0.9 9.0 0.6 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Rib_5-P_isom_A PF06026.14 EMG46154.1 - 2.9e-61 206.0 0.0 3.5e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EMG46154.1 - 0.0012 18.8 0.0 0.87 9.5 0.0 2.2 1 1 1 2 2 2 2 DeoR C terminal sensor domain DUF2744 PF10910.8 EMG46154.1 - 0.033 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) Ribosomal_S7e PF01251.18 EMG46155.1 - 9.8e-79 263.4 1.6 1.1e-78 263.3 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SH3_1 PF00018.28 EMG46156.1 - 2.1e-24 84.9 0.6 3.1e-12 45.9 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EMG46156.1 - 4.1e-24 84.2 0.3 2e-14 53.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 EMG46156.1 - 7.7e-19 67.8 0.2 2.7e-18 66.0 0.2 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 EMG46156.1 - 4.2e-14 52.0 0.0 7.5e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 EMG46156.1 - 0.00027 21.0 0.0 1.6 8.9 0.0 3.2 3 0 0 3 3 3 2 SH3 domain SH3_3 PF08239.11 EMG46156.1 - 0.02 15.1 0.3 0.06 13.6 0.1 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain DUF1664 PF07889.12 EMG46156.1 - 0.72 9.9 3.7 0.66 10.0 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3086 PF11285.8 EMG46156.1 - 2.5 7.1 6.6 0.54 9.3 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3086) DUF4456 PF14644.6 EMG46157.1 - 0.045 13.4 0.1 0.045 13.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) End3 PF12761.7 EMG46158.1 - 2.1e-67 227.1 9.2 2.9e-67 226.7 9.2 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EMG46158.1 - 9.4e-54 179.8 2.0 4.6e-53 177.6 0.2 2.5 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EMG46158.1 - 1.1e-05 24.6 0.1 1.1e-05 24.6 0.1 2.9 3 0 0 3 3 2 1 EF hand EF-hand_8 PF13833.6 EMG46158.1 - 0.00037 20.3 0.0 0.00096 19.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 EMG46158.1 - 0.00052 20.4 0.0 0.00052 20.4 0.0 3.2 4 1 1 5 5 4 1 EF-hand domain pair DUF812 PF05667.11 EMG46158.1 - 0.0019 17.2 7.6 0.0024 16.9 7.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) EF-hand_6 PF13405.6 EMG46158.1 - 0.012 15.5 0.1 0.012 15.5 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain Fib_alpha PF08702.10 EMG46158.1 - 0.044 14.0 10.9 0.07 13.3 10.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family EF-hand_5 PF13202.6 EMG46158.1 - 0.05 13.1 0.2 0.05 13.1 0.2 3.1 3 0 0 3 3 2 0 EF hand PRKG1_interact PF15898.5 EMG46158.1 - 0.66 10.9 11.0 1.6 9.7 11.0 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain LMBR1 PF04791.16 EMG46158.1 - 1.1 8.1 3.8 1.6 7.6 3.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4140 PF13600.6 EMG46158.1 - 1.9 9.0 6.6 17 5.9 2.0 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Complex1_30kDa PF00329.19 EMG46159.1 - 1.5e-46 158.0 0.0 2.1e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit SCP2 PF02036.17 EMG46160.1 - 1.9e-23 82.9 3.1 2.2e-23 82.7 3.1 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EMG46160.1 - 0.00044 20.5 0.9 0.00061 20.1 0.9 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Toxin_R_bind_N PF07953.12 EMG46160.1 - 0.063 13.0 0.1 0.15 11.8 0.1 1.7 1 1 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding RRT14 PF17075.5 EMG46161.1 - 1.2e-53 182.2 20.1 1.7e-53 181.7 20.1 1.2 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 DUF4765 PF15962.5 EMG46161.1 - 0.0039 15.2 9.6 0.0048 14.9 9.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4765) GRDP-like PF07173.12 EMG46161.1 - 0.084 13.5 4.5 0.13 12.9 4.5 1.3 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like MMS19_N PF14500.6 EMG46162.1 - 3.8e-78 262.7 5.0 7.1e-78 261.8 1.7 2.7 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EMG46162.1 - 1.7e-76 258.1 24.6 1.7e-76 258.1 24.6 3.4 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal Ipi1_N PF12333.8 EMG46162.1 - 0.0026 18.3 1.1 0.037 14.6 0.0 3.3 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation NUC130_3NT PF08158.12 EMG46162.1 - 0.033 14.5 2.8 57 4.1 0.0 4.7 4 0 0 4 4 4 0 NUC130/3NT domain MOR2-PAG1_N PF14222.6 EMG46163.1 - 5e-169 563.8 9.2 9.7e-169 562.8 9.2 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EMG46163.1 - 7.6e-74 248.8 2.1 7.6e-73 245.5 0.0 3.4 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EMG46163.1 - 1.3e-31 109.2 11.0 1.5e-12 46.0 0.2 4.4 3 2 0 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.7 EMG46163.1 - 0.02 14.9 5.8 0.54 10.3 0.0 4.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EMG46163.1 - 0.08 13.2 0.1 3.9 8.0 0.0 3.7 2 0 0 2 2 2 0 HEAT repeat RTP1_C1 PF10363.9 EMG46163.1 - 0.17 12.1 1.0 4 7.7 0.1 3.9 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Eisosome1 PF12757.7 EMG46165.1 - 2.9e-23 82.5 8.7 2.9e-23 82.5 8.7 6.0 3 1 3 6 6 6 1 Eisosome protein 1 FAM60A PF15396.6 EMG46166.1 - 3.1 7.8 9.1 3.5 7.6 9.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Mitofilin PF09731.9 EMG46166.1 - 9.8 4.9 19.2 11 4.7 19.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Gpr1_Fun34_YaaH PF01184.19 EMG46167.1 - 1.3e-85 286.2 24.3 1.5e-85 286.0 24.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SQS_PSY PF00494.19 EMG46168.1 - 1.1e-21 77.5 0.0 1.4e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Pro_isomerase PF00160.21 EMG46169.1 - 3.1e-10 40.6 0.0 5.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-RING_2 PF13639.6 EMG46170.1 - 1.5e-09 38.1 9.0 7.6e-09 35.8 4.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EMG46170.1 - 2.4e-07 30.9 2.3 2.4e-07 30.9 2.3 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EMG46170.1 - 1.9e-05 24.6 6.5 0.00016 21.6 2.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EMG46170.1 - 3.6e-05 23.5 2.2 3.6e-05 23.5 2.2 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EMG46170.1 - 0.00028 20.7 7.8 0.0011 18.8 3.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMG46170.1 - 0.0011 18.8 7.5 0.0011 18.8 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMG46170.1 - 0.0015 18.4 7.4 0.015 15.2 3.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EMG46170.1 - 0.003 17.4 8.0 0.0044 16.8 3.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EMG46170.1 - 0.0089 16.1 2.1 0.031 14.3 1.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EMG46170.1 - 0.045 13.5 4.2 0.76 9.6 0.5 2.4 2 0 0 2 2 2 0 RING-like zinc finger FANCL_C PF11793.8 EMG46170.1 - 0.52 10.5 3.5 1.3 9.3 0.9 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EMG46170.1 - 3.3 7.9 8.4 0.39 10.9 3.9 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING LRR_4 PF12799.7 EMG46171.1 - 0.023 15.1 34.8 0.41 11.2 1.6 7.3 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EMG46171.1 - 0.031 14.2 0.4 0.22 11.4 0.6 2.3 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EMG46171.1 - 0.072 13.0 0.2 0.93 9.5 0.1 2.8 3 0 0 3 3 3 0 F-box domain PRANC PF09372.10 EMG46171.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.5 3 0 0 3 3 3 0 PRANC domain LRR_2 PF07723.13 EMG46171.1 - 0.3 11.8 4.8 5.9 7.7 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 EMG46171.1 - 0.82 9.5 24.8 0.072 12.9 10.1 4.5 5 0 0 5 5 5 0 Leucine rich repeat DUF1358 PF07096.11 EMG46172.1 - 0.0088 16.0 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) CC PF04942.14 EMG46172.1 - 0.023 14.9 0.1 0.039 14.2 0.1 1.3 1 0 0 1 1 1 0 CC domain Lon_C PF05362.13 EMG46173.1 - 3.8e-43 147.4 0.0 6.6e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EMG46173.1 - 4.3e-27 95.4 3.4 1.9e-26 93.2 1.1 2.4 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EMG46173.1 - 1.2e-23 84.0 0.0 3.2e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMG46173.1 - 3.3e-07 30.4 0.0 9.5e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMG46173.1 - 2.7e-06 27.6 0.0 6.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 EMG46173.1 - 7e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EMG46173.1 - 0.00011 22.6 0.0 0.00032 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMG46173.1 - 0.00019 22.0 0.4 0.0021 18.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EMG46173.1 - 0.00063 19.5 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMG46173.1 - 0.0008 19.7 0.0 0.047 14.0 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EMG46173.1 - 0.00095 19.0 0.0 0.0025 17.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EMG46173.1 - 0.0034 17.6 0.0 0.0088 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMG46173.1 - 0.0038 17.3 0.0 0.024 14.7 0.0 2.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMG46173.1 - 0.0066 16.4 0.2 0.021 14.7 0.2 1.9 1 0 0 1 1 1 1 RsgA GTPase TIP49 PF06068.13 EMG46173.1 - 0.011 14.9 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Rad17 PF03215.15 EMG46173.1 - 0.011 15.6 0.1 0.96 9.3 0.0 2.9 1 1 1 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 EMG46173.1 - 0.023 15.1 0.0 0.1 13.0 0.0 2.2 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 EMG46173.1 - 0.025 14.6 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EMG46173.1 - 0.028 13.7 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EMG46173.1 - 0.032 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 EMG46173.1 - 0.034 13.5 0.0 0.084 12.2 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EMG46173.1 - 0.037 13.8 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 EMG46173.1 - 0.078 12.7 0.1 0.078 12.7 0.1 2.4 2 1 1 3 3 3 0 AAA domain PhoH PF02562.16 EMG46173.1 - 0.082 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EMG46173.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMG46173.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PBP1_TM PF14812.6 EMG46173.1 - 0.25 11.7 7.8 0.049 14.0 2.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_23 PF13476.6 EMG46173.1 - 0.31 11.5 0.0 0.31 11.5 0.0 4.5 2 1 0 3 3 2 0 AAA domain Asp PF00026.23 EMG46174.1 - 5.3e-61 206.8 8.2 7.6e-61 206.3 8.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMG46174.1 - 1.1e-08 35.6 0.1 1.1e-07 32.2 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMG46174.1 - 0.013 16.1 0.9 25 5.6 0.0 3.9 3 0 0 3 3 3 0 Aspartyl protease TAXi_C PF14541.6 EMG46174.1 - 0.013 15.3 0.0 0.46 10.2 0.0 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal RIBIOP_C PF04950.12 EMG46175.1 - 3.1e-90 302.5 0.6 3.1e-90 302.5 0.6 3.2 3 0 0 3 3 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EMG46175.1 - 3.1e-30 104.1 0.1 2.3e-29 101.3 0.0 2.7 2 0 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 EMG46175.1 - 2.1e-06 27.4 0.0 0.0011 18.6 0.0 2.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EMG46175.1 - 5.1e-06 26.9 0.0 1.5e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMG46175.1 - 1.1e-05 25.9 0.0 3.4e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EMG46175.1 - 1.8e-05 24.9 0.0 8.8e-05 22.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMG46175.1 - 0.00019 21.7 0.0 0.00063 20.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EMG46175.1 - 0.00038 20.5 0.3 0.003 17.6 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EMG46175.1 - 0.0006 20.3 1.8 0.0023 18.4 0.0 2.8 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 EMG46175.1 - 0.00076 19.8 0.2 0.0033 17.8 0.0 2.2 2 0 0 2 2 1 1 RNA helicase AAA_5 PF07728.14 EMG46175.1 - 0.0087 16.1 0.1 0.028 14.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EMG46175.1 - 0.0092 15.9 0.3 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 EMG46175.1 - 0.0095 16.5 4.0 0.025 15.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 EMG46175.1 - 0.015 15.2 0.1 0.04 13.8 0.1 1.7 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 EMG46175.1 - 0.016 15.4 0.0 0.061 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMG46175.1 - 0.022 15.1 0.0 0.073 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMG46175.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EMG46175.1 - 0.024 14.4 0.0 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EMG46175.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.6 EMG46175.1 - 0.031 14.1 0.0 0.031 14.1 0.0 4.5 3 1 0 3 3 2 0 AAA domain NACHT PF05729.12 EMG46175.1 - 0.045 13.7 0.1 0.13 12.1 0.1 1.8 1 1 0 1 1 1 0 NACHT domain cobW PF02492.19 EMG46175.1 - 0.1 12.2 0.1 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EMG46175.1 - 0.23 11.2 1.1 0.31 10.7 0.0 1.8 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase Transket_pyr PF02779.24 EMG46177.1 - 3.1e-65 219.2 0.0 5.5e-65 218.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EMG46177.1 - 5e-62 209.5 0.0 7e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EMG46177.1 - 1.8e-49 167.4 0.0 3e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EMG46177.1 - 8.2e-20 70.1 3.7 8.2e-20 70.1 3.7 2.0 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 EMG46177.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 DUF676 PF05057.14 EMG46178.1 - 1.1e-47 162.4 0.0 2.4e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase PF00151.19 EMG46178.1 - 0.0033 16.8 1.4 0.005 16.2 0.0 1.8 2 0 0 2 2 2 1 Lipase LCAT PF02450.15 EMG46178.1 - 0.0052 16.0 0.8 0.021 14.0 0.0 2.0 1 1 0 2 2 2 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 EMG46178.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 EMG46178.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) adh_short PF00106.25 EMG46179.1 - 9.6e-45 152.4 0.0 1.2e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG46179.1 - 4.2e-27 95.2 0.0 5.2e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EMG46179.1 - 6.1e-06 25.8 0.0 0.0022 17.4 0.0 2.6 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) KR PF08659.10 EMG46179.1 - 8.5e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMG46179.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMG46179.1 - 0.0016 18.0 0.0 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 EMG46179.1 - 0.0076 16.0 0.4 0.056 13.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EutB PF06751.11 EMG46179.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) PRKG1_interact PF15898.5 EMG46180.1 - 0.016 16.1 5.5 0.016 16.1 5.5 6.9 4 2 2 6 6 6 0 cGMP-dependent protein kinase interacting domain zf-RING_9 PF13901.6 EMG46181.1 - 0.16 12.0 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon LRR_4 PF12799.7 EMG46183.1 - 5.2e-14 52.1 92.6 0.0035 17.7 7.6 12.9 4 3 6 14 14 14 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG46183.1 - 1.1e-12 47.5 67.7 0.00032 20.4 5.3 10.0 3 2 6 10 10 10 7 Leucine rich repeat LRR_9 PF14580.6 EMG46183.1 - 0.0015 18.1 23.2 0.067 12.7 0.7 5.0 2 1 4 6 6 6 2 Leucine-rich repeat Rtt106 PF08512.12 EMG46183.1 - 0.097 13.1 2.6 2.7 8.5 0.1 3.3 3 0 0 3 3 3 0 Histone chaperone Rttp106-like FNIP PF05725.12 EMG46183.1 - 0.4 10.9 43.7 0.12 12.6 0.8 9.1 7 3 0 7 7 7 0 FNIP Repeat LRR_2 PF07723.13 EMG46183.1 - 1.4 9.7 6.5 22 5.9 0.1 5.4 4 0 0 4 4 4 0 Leucine Rich Repeat Fer2 PF00111.27 EMG46184.1 - 1.6e-14 53.6 0.4 2.1e-14 53.2 0.4 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain V-SNARE_C PF12352.8 EMG46185.1 - 1.3e-19 70.3 7.3 1.3e-19 70.3 7.3 2.7 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EMG46185.1 - 4.4e-14 52.6 5.4 4.4e-14 52.6 5.4 3.5 2 2 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Use1 PF09753.9 EMG46185.1 - 0.002 17.9 3.8 0.0045 16.7 3.8 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF4407 PF14362.6 EMG46185.1 - 0.015 14.7 7.1 0.028 13.8 7.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) EMC3_TMCO1 PF01956.16 EMG46185.1 - 0.015 15.0 0.0 0.047 13.4 0.0 1.9 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CENP-H PF05837.12 EMG46185.1 - 0.022 15.2 9.7 0.051 14.0 1.9 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Sec20 PF03908.13 EMG46185.1 - 0.029 14.3 7.3 0.073 13.0 1.0 2.7 2 2 1 3 3 3 0 Sec20 7TMR-HDED PF07697.11 EMG46185.1 - 0.048 13.8 7.0 0.066 13.3 7.0 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Prominin PF05478.11 EMG46185.1 - 0.08 10.9 7.7 0.21 9.5 0.4 2.1 2 0 0 2 2 2 0 Prominin Fusion_gly PF00523.18 EMG46185.1 - 0.11 10.7 7.1 0.2 9.9 1.2 2.2 1 1 1 2 2 2 0 Fusion glycoprotein F0 YqjK PF13997.6 EMG46185.1 - 0.12 12.6 1.7 0.85 9.9 0.0 2.6 3 1 0 3 3 2 0 YqjK-like protein Prefoldin_2 PF01920.20 EMG46185.1 - 0.2 11.6 7.2 1.7 8.6 0.4 3.2 2 1 1 3 3 3 0 Prefoldin subunit Tup_N PF08581.10 EMG46185.1 - 0.43 10.9 6.8 0.15 12.3 1.7 2.6 2 1 1 3 3 3 0 Tup N-terminal Exonuc_VII_L PF02601.15 EMG46185.1 - 1.9 8.0 12.6 6 6.3 12.6 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin PF02996.17 EMG46185.1 - 2 8.4 6.9 11 5.9 0.1 3.3 3 0 0 3 3 3 0 Prefoldin subunit KapB PF08810.10 EMG46185.1 - 2.8 8.1 6.2 3.7 7.7 0.4 2.9 2 1 1 3 3 3 0 Kinase associated protein B FliJ PF02050.16 EMG46185.1 - 3.6 7.8 12.4 3.9 7.7 4.0 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein PMC2NT PF08066.12 EMG46185.1 - 4.1 8.2 6.8 2.2 9.0 0.5 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Uso1_p115_C PF04871.13 EMG46185.1 - 8.4 6.8 9.1 1.1 9.7 2.2 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TAFII28 PF04719.14 EMG46186.1 - 3.2e-27 94.4 0.8 1.5e-26 92.3 0.8 2.0 1 1 0 1 1 1 1 hTAFII28-like protein conserved region Nop14 PF04147.12 EMG46186.1 - 8.5 4.4 22.3 13 3.9 22.3 1.3 1 0 0 1 1 1 0 Nop14-like family AA_permease PF00324.21 EMG46187.1 - 8.1e-101 338.0 41.3 1e-100 337.7 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG46187.1 - 1.5e-31 109.7 43.8 1.8e-31 109.4 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3533 PF12051.8 EMG46188.1 - 5.1e-97 325.2 17.0 6.1e-97 324.9 17.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Transp_cyt_pur PF02133.15 EMG46189.1 - 4e-44 151.1 29.2 4.9e-44 150.8 29.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3533 PF12051.8 EMG46190.1 - 5e-113 377.9 16.2 5.8e-113 377.6 16.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF5516 PF17637.2 EMG46190.1 - 0.026 14.3 3.0 0.059 13.1 1.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5516) Glyco_hydro_63 PF03200.16 EMG46191.1 - 1.4e-08 33.9 7.1 2.8e-05 23.1 0.2 4.4 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain DUF1706 PF08020.11 EMG46191.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) UDPGT PF00201.18 EMG46191.1 - 0.064 12.0 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase TMA7 PF09072.10 EMG46191.1 - 0.24 12.3 0.7 0.48 11.3 0.0 1.9 2 0 0 2 2 2 0 Translation machinery associated TMA7 TRP PF06011.12 EMG46192.1 - 7.1e-145 483.0 30.7 1e-144 482.4 30.7 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EMG46192.1 - 3.7e-42 144.0 1.0 9e-42 142.7 1.0 1.7 1 0 0 1 1 1 1 ML-like domain DUF4410 PF14366.6 EMG46192.1 - 0.01 15.8 1.2 0.017 15.0 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) Neur_chan_memb PF02932.16 EMG46192.1 - 0.012 15.7 3.6 0.083 12.9 0.1 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 EMG46192.1 - 1.1 8.9 6.2 13 5.4 6.2 2.3 1 1 0 1 1 1 0 Connexin ABC_tran PF00005.27 EMG46193.1 - 6.5e-58 195.1 0.0 3.7e-34 118.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMG46193.1 - 1.1e-54 185.9 36.8 1.9e-35 122.9 14.4 3.3 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EMG46193.1 - 4.9e-08 32.7 2.9 0.0057 16.1 0.9 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMG46193.1 - 5.8e-08 33.5 6.2 0.00057 20.4 0.1 3.2 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EMG46193.1 - 1.3e-06 28.5 0.0 0.023 14.6 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 EMG46193.1 - 1.4e-06 28.0 0.1 0.0092 15.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EMG46193.1 - 2.8e-06 27.4 3.6 0.059 13.2 0.1 3.4 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EMG46193.1 - 0.0001 22.4 1.4 0.014 15.5 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EMG46193.1 - 0.00099 19.4 0.2 1.3 9.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 EMG46193.1 - 0.0011 18.7 0.2 0.076 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMG46193.1 - 0.0019 18.6 0.1 0.84 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 EMG46193.1 - 0.002 17.9 4.8 0.28 10.8 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_7 PF12775.7 EMG46193.1 - 0.0093 15.5 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 EMG46193.1 - 0.015 15.0 0.0 6.9 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EMG46193.1 - 0.032 13.5 0.1 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 EMG46193.1 - 0.043 13.4 0.1 0.72 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EMG46193.1 - 0.043 12.8 0.1 0.074 12.0 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CENP-B_dimeris PF09026.10 EMG46193.1 - 0.094 13.1 0.9 0.24 11.8 0.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain T2SSE PF00437.20 EMG46193.1 - 0.11 11.5 0.1 10 5.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.29 EMG46193.1 - 0.14 12.6 0.9 40 4.6 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EMG46193.1 - 0.56 10.2 3.7 0.56 10.3 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain Roc PF08477.13 EMG46193.1 - 0.58 10.4 4.5 17 5.7 0.0 3.3 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EMG46193.1 - 0.59 9.7 3.2 5.1 6.6 0.5 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RRM_1 PF00076.22 EMG46194.1 - 2.1e-25 88.3 12.1 1.2e-14 53.8 4.2 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMG46194.1 - 0.00018 21.6 0.3 0.0093 16.1 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 EMG46194.1 - 0.00081 19.2 0.2 0.75 9.7 0.0 2.8 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EMG46194.1 - 0.022 14.8 1.1 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 Limkain b1 DbpA PF03880.15 EMG46194.1 - 0.054 13.5 0.4 12 6.0 0.0 2.5 2 0 0 2 2 2 0 DbpA RNA binding domain PIG-L PF02585.17 EMG46194.1 - 0.061 14.0 0.1 0.17 12.5 0.1 1.7 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase Glyco_transf_6 PF03414.13 EMG46194.1 - 0.086 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 6 BRAP2 PF07576.12 EMG46194.1 - 0.11 12.8 3.2 1.8 8.8 0.8 2.4 2 0 0 2 2 2 0 BRCA1-associated protein 2 Nup35_RRM_2 PF14605.6 EMG46194.1 - 0.38 10.8 1.2 7.2 6.7 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF3381 PF11861.8 EMG46194.1 - 7.7 6.3 24.6 0.39 10.5 14.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3381) Carn_acyltransf PF00755.20 EMG46195.1 - 5.8e-145 484.2 0.1 7.2e-145 483.9 0.1 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Erf4 PF10256.9 EMG46195.1 - 0.027 14.6 0.7 2.4 8.3 0.0 3.8 3 1 1 4 4 4 0 Golgin subfamily A member 7/ERF4 family RVT_1 PF00078.27 EMG46196.1 - 1.6e-27 96.5 0.2 4.7e-27 94.9 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3990 PF13151.6 EMG46196.1 - 0.1 12.3 0.6 0.42 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) zf-C2H2_10 PF16588.5 EMG46196.1 - 1.7 8.5 6.4 6 6.7 6.4 2.0 1 0 0 1 1 1 0 C2H2 zinc-finger UPF0113 PF03657.13 EMG46197.1 - 0.036 14.3 0.1 1.7 9.0 0.0 2.7 3 0 0 3 3 3 0 UPF0113 PUA domain PhoLip_ATPase_C PF16212.5 EMG46198.1 - 1.1e-76 257.9 27.4 1.1e-76 257.9 27.4 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMG46198.1 - 2.2e-17 62.5 1.5 8.6e-17 60.6 1.5 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EMG46198.1 - 4.4e-12 45.9 0.0 1.4e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMG46198.1 - 5.4e-12 46.4 2.5 4e-07 30.5 0.4 3.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EMG46198.1 - 0.00059 19.4 0.7 0.00059 19.4 0.7 2.9 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EMG46198.1 - 0.019 14.7 7.5 0.085 12.6 5.7 2.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Lactamase_B_6 PF16661.5 EMG46199.1 - 1.3e-65 220.5 0.0 2.3e-65 219.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EMG46199.1 - 2.8e-25 89.5 14.5 7.5e-25 88.1 0.0 3.6 3 0 0 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EMG46199.1 - 6.6e-11 42.5 0.0 5.1e-10 39.6 0.0 2.6 2 0 0 2 2 2 1 Beta-Casp domain Ndufs5 PF10200.9 EMG46199.1 - 4.8e-05 23.5 0.3 4.8e-05 23.5 0.3 2.6 2 1 0 2 2 2 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UPF0203 PF05254.12 EMG46199.1 - 0.034 14.4 1.2 0.14 12.4 1.2 2.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 EMG46199.1 - 0.1 12.8 1.1 15 5.9 0.2 3.3 2 1 1 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.13 EMG46199.1 - 5.7 7.2 5.8 26 5.1 1.1 2.4 1 1 1 2 2 2 0 CHCH domain NPR2 PF06218.11 EMG46201.1 - 2e-208 692.6 12.9 2.5e-207 689.0 9.9 2.0 2 0 0 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.13 EMG46201.1 - 0.81 8.4 0.0 0.81 8.4 0.0 4.0 3 1 1 4 4 4 0 Nitrogen Permease regulator of amino acid transport activity 3 CENP-B_dimeris PF09026.10 EMG46201.1 - 0.91 10.0 27.3 2.9 8.3 17.5 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF3295 PF11702.8 EMG46201.1 - 2.5 7.4 14.5 5.8 6.2 14.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) NOA36 PF06524.12 EMG46201.1 - 8 5.7 20.8 0.71 9.1 12.0 2.5 2 0 0 2 2 2 0 NOA36 protein SF1-HH PF16275.5 EMG46202.1 - 6.9e-34 116.6 4.1 6.9e-34 116.6 4.1 2.6 3 0 0 3 3 3 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 EMG46202.1 - 6e-08 32.4 0.0 1.5e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 EMG46202.1 - 1.8e-05 24.6 1.3 3e-05 23.9 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EMG46202.1 - 0.0083 16.1 0.3 0.021 14.8 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EMG46202.1 - 0.069 12.9 1.2 0.14 12.0 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 EMG46202.1 - 0.085 13.3 0.9 0.18 12.2 0.2 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.6 EMG46202.1 - 0.17 11.8 4.0 0.34 10.8 4.0 1.5 1 0 0 1 1 1 0 Zinc knuckle DEAD_assoc PF08494.11 EMG46202.1 - 0.23 11.2 0.3 0.59 9.9 0.0 1.7 2 0 0 2 2 2 0 DEAD/H associated MTS PF05175.14 EMG46203.1 - 7.8e-08 32.1 0.1 1.3e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EMG46203.1 - 0.00044 20.1 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EMG46203.1 - 0.0014 18.5 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.13 EMG46203.1 - 0.0047 16.3 0.4 0.043 13.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EMG46203.1 - 0.0075 17.0 0.1 0.024 15.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 EMG46203.1 - 0.0079 15.9 0.1 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EMG46203.1 - 0.0088 16.7 0.0 0.018 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EMG46203.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.17 EMG46203.1 - 0.047 13.2 0.1 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_11 PF08241.12 EMG46203.1 - 0.047 14.3 0.0 0.11 13.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain GCD14 PF08704.10 EMG46203.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit TPR_14 PF13428.6 EMG46204.1 - 5e-11 42.5 0.0 0.24 12.3 0.0 7.3 6 2 2 8 8 8 3 Tetratricopeptide repeat HAT PF02184.16 EMG46204.1 - 1.3e-09 37.8 35.5 0.0043 17.0 0.0 9.9 10 1 1 11 11 11 5 HAT (Half-A-TPR) repeat Suf PF05843.14 EMG46204.1 - 1.4e-09 38.3 23.9 5.2e-06 26.7 0.9 5.7 3 2 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EMG46204.1 - 3.8e-05 24.1 0.0 0.013 16.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMG46204.1 - 0.0064 17.1 2.2 21 6.0 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMG46204.1 - 0.088 13.5 0.0 17 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EMG46204.1 - 0.12 12.4 0.1 0.12 12.4 0.1 5.8 4 2 3 7 7 7 0 U3 small nucleolar RNA-associated protein 6 Histone PF00125.24 EMG46205.1 - 1.8e-17 63.9 0.0 2.3e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EMG46205.1 - 1.1e-13 50.6 0.8 1.8e-13 49.9 0.8 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EMG46205.1 - 7.7e-05 22.9 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone OPA3 PF07047.12 EMG46206.1 - 1e-46 157.8 0.7 1.3e-46 157.4 0.7 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF5320 PF17253.2 EMG46206.1 - 0.027 15.5 0.0 0.05 14.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) IU_nuc_hydro PF01156.19 EMG46207.1 - 2e-34 119.6 0.0 2.3e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF1593 PF07632.11 EMG46207.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) Pkinase PF00069.25 EMG46208.1 - 4e-53 180.5 8.0 9.6e-53 179.2 8.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG46208.1 - 5.2e-30 104.6 2.1 3e-29 102.1 2.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG46208.1 - 9.5e-08 31.2 0.1 2.8e-07 29.7 0.1 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EMG46208.1 - 0.00079 18.8 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Blo-t-5 PF11642.8 EMG46208.1 - 0.26 11.3 0.0 0.26 11.3 0.0 2.9 2 1 1 3 3 3 0 Mite allergen Blo t 5 Ank_4 PF13637.6 EMG46209.1 - 3.9e-16 59.2 1.7 1e-06 29.1 0.1 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMG46209.1 - 7.3e-13 48.9 2.3 1.1e-06 29.1 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMG46209.1 - 1.8e-10 40.9 1.4 1.3e-06 28.5 0.1 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMG46209.1 - 2e-09 36.9 0.1 0.0012 19.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EMG46209.1 - 1.1e-08 35.1 0.0 0.17 12.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 EMG46209.1 - 4.8e-06 26.4 2.8 1.5e-05 24.8 0.1 3.2 2 2 0 2 2 2 1 KilA-N domain Rho_GDI PF02115.17 EMG46210.1 - 0.058 13.1 0.5 0.23 11.2 0.0 1.9 1 1 1 2 2 2 0 RHO protein GDP dissociation inhibitor zinc_ribbon_10 PF10058.9 EMG46211.1 - 6.8e-22 77.0 0.2 1.3e-21 76.0 0.2 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein PIG-P PF08510.12 EMG46211.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 PIG-P DUF2207 PF09972.9 EMG46211.1 - 0.065 12.0 0.4 0.09 11.5 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase_fungal PF17667.1 EMG46211.1 - 0.076 11.8 0.6 0.12 11.1 0.6 1.2 1 0 0 1 1 1 0 Fungal protein kinase ATP11 PF06644.11 EMG46211.1 - 0.099 12.4 6.8 0.21 11.3 6.8 1.5 1 0 0 1 1 1 0 ATP11 protein CCDC-167 PF15188.6 EMG46211.1 - 0.19 12.1 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DivIC PF04977.15 EMG46211.1 - 0.27 11.0 0.1 0.27 11.0 0.1 2.6 2 1 0 2 2 2 0 Septum formation initiator Pex14_N PF04695.13 EMG46211.1 - 2.2 8.9 18.1 0.32 11.6 11.5 2.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SARAF PF06682.12 EMG46211.1 - 3.1 7.3 6.5 7.2 6.2 6.5 1.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3729 PF12526.8 EMG46211.1 - 4.6 8.8 14.8 0.92 11.1 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) XhlA PF10779.9 EMG46211.1 - 5.5 7.3 7.3 0.9 9.8 0.1 2.5 2 1 0 2 2 2 0 Haemolysin XhlA NAC PF01849.18 EMG46212.1 - 6.9e-18 64.4 0.3 7.6e-17 61.0 0.1 2.3 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.6 EMG46212.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain RNA_pol_Rpo13 PF12136.8 EMG46212.1 - 0.066 13.1 6.1 0.16 11.9 6.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain CSN5_C PF18323.1 EMG46212.1 - 6 7.8 8.1 16 6.5 8.0 1.8 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Nop53 PF07767.11 EMG46212.1 - 6.3 6.1 15.5 0.18 11.2 9.6 1.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Hist_deacetyl PF00850.19 EMG46213.1 - 9.7e-83 278.1 0.0 1.2e-82 277.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain P66_CC PF16563.5 EMG46213.1 - 1.3 8.7 4.0 2.3 7.9 4.0 1.3 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Proteasome PF00227.26 EMG46214.1 - 1.9e-43 148.2 0.2 2.5e-43 147.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMG46214.1 - 1.5e-14 53.3 0.1 2.8e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PfaD_N PF18328.1 EMG46214.1 - 0.034 14.1 0.1 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Fatty acid synthase subunit PfaD N-terminal domain CBM64 PF18666.1 EMG46214.1 - 0.15 12.2 0.0 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate-binding module 64 ERG4_ERG24 PF01222.17 EMG46215.1 - 3.4e-155 517.0 26.5 4e-155 516.8 26.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Pyr_redox_2 PF07992.14 EMG46217.1 - 7.6e-53 179.7 0.0 9.4e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMG46217.1 - 1e-09 38.8 0.6 3.4e-08 33.9 0.2 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMG46217.1 - 0.0059 15.9 1.6 0.23 10.7 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Mod_r PF07200.13 EMG46218.1 - 3.7e-23 82.3 20.9 4.3e-23 82.0 20.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein CK2S PF15011.6 EMG46218.1 - 0.018 14.9 5.2 0.03 14.2 5.2 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate FadA PF09403.10 EMG46218.1 - 0.02 15.3 11.0 0.02 15.3 11.0 2.7 1 1 1 2 2 2 0 Adhesion protein FadA Cep57_MT_bd PF06657.13 EMG46218.1 - 0.026 15.0 3.7 0.026 15.0 3.7 1.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FAD_SOX PF18371.1 EMG46218.1 - 0.23 11.9 3.9 0.14 12.6 1.5 1.8 1 1 1 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Cytochrom_B562 PF07361.11 EMG46218.1 - 1.1 9.9 7.4 2.3 8.9 0.4 2.6 2 1 0 2 2 2 0 Cytochrome b562 Arc_PepC_II PF06847.11 EMG46218.1 - 1.6 9.3 8.0 1.4 9.5 1.2 2.6 1 1 2 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II Exonuc_VII_L PF02601.15 EMG46218.1 - 3 7.3 7.1 4.3 6.8 7.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MFS_1 PF07690.16 EMG46219.1 - 5.4e-42 144.0 26.0 2.4e-39 135.3 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3589 PF12141.8 EMG46220.1 - 1.5e-135 452.6 0.0 6.3e-134 447.2 0.0 2.0 1 1 0 1 1 1 1 Beta-mannosyltransferases Chitin_synth_1 PF01644.17 EMG46221.1 - 2.5e-64 216.2 0.0 4.2e-64 215.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EMG46221.1 - 2.9e-25 88.0 0.1 6.3e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EMG46221.1 - 1.5e-19 70.1 1.5 9e-16 57.6 0.0 2.9 3 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EMG46221.1 - 4e-13 49.7 1.0 2.4e-12 47.2 1.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMG46221.1 - 0.00051 20.0 0.0 0.0016 18.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EMG46221.1 - 0.026 14.0 0.0 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 Baculo_11_kDa PF06143.11 EMG46221.1 - 0.12 11.9 0.3 28 4.4 1.2 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family Spt5_N PF11942.8 EMG46221.1 - 0.25 12.3 5.7 4.9 8.2 0.4 3.4 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF3984 PF13136.6 EMG46221.1 - 2.5 7.4 6.1 5.2 6.4 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Vps8 PF12816.7 EMG46222.1 - 3.4e-55 186.6 6.6 1.3e-54 184.7 6.6 2.2 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 WD40 PF00400.32 EMG46222.1 - 0.0014 19.4 0.9 0.0056 17.5 0.1 2.6 2 0 0 2 2 1 1 WD domain, G-beta repeat Cauli_AT PF03233.13 EMG46222.1 - 0.009 15.9 0.6 0.073 13.0 0.0 2.7 2 0 0 2 2 2 1 Aphid transmission protein zf-RING_5 PF14634.6 EMG46222.1 - 0.041 13.9 0.3 0.13 12.3 0.3 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Membr_traf_MHD PF10540.9 EMG46222.1 - 0.088 13.0 3.5 6.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Munc13 (mammalian uncoordinated) homology domain ANAPC4_WD40 PF12894.7 EMG46222.1 - 0.12 12.7 0.1 0.62 10.4 0.0 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EMG46222.1 - 0.13 12.1 11.6 4.5 7.1 0.1 4.1 3 1 1 4 4 4 0 Region in Clathrin and VPS zf-RING_2 PF13639.6 EMG46222.1 - 0.13 12.6 0.3 0.5 10.7 0.3 2.0 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EMG46222.1 - 0.59 10.0 3.0 0.71 9.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMG46222.1 - 1.1 9.6 2.9 2.1 8.7 0.5 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain Vps39_1 PF10366.9 EMG46222.1 - 1.4 9.3 0.0 1.4 9.3 0.0 4.2 6 0 0 6 6 6 0 Vacuolar sorting protein 39 domain 1 FNIP PF05725.12 EMG46223.1 - 0.065 13.4 14.1 4.3 7.6 0.2 6.8 6 1 0 6 6 6 0 FNIP Repeat Sigma70_ner PF04546.13 EMG46223.1 - 0.13 12.2 6.0 0.3 11.0 6.0 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 EMG46223.1 - 0.89 7.8 6.1 1.3 7.2 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EMG46223.1 - 2.5 6.1 18.3 3.7 5.5 18.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EMG46223.1 - 2.7 7.2 11.9 4 6.7 11.9 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EMG46223.1 - 2.8 6.0 10.6 4.2 5.5 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family Spt5_N PF11942.8 EMG46223.1 - 3.3 8.7 15.6 7.5 7.6 15.6 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal YL1 PF05764.13 EMG46223.1 - 7.5 6.6 13.7 14 5.7 13.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein adh_short PF00106.25 EMG46225.1 - 1.9e-88 295.0 8.4 3.9e-48 163.5 0.4 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMG46225.1 - 3.6e-72 242.7 7.8 2.9e-40 138.3 0.9 3.1 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG46225.1 - 1.9e-35 122.4 2.8 7.6e-17 61.8 0.1 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 EMG46225.1 - 2.7e-32 110.9 0.0 5.8e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain PglL_A PF15864.5 EMG46225.1 - 0.24 11.2 4.6 4.9 7.0 0.3 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase GCIP PF13324.6 EMG46225.1 - 0.5 9.9 3.1 0.91 9.1 3.1 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 EMG46225.1 - 7.8 5.7 8.6 12 5.1 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein Rhodanese PF00581.20 EMG46226.1 - 2e-12 47.6 0.1 5.1e-12 46.3 0.1 1.8 1 0 0 1 1 1 1 Rhodanese-like domain E1-E2_ATPase PF00122.20 EMG46227.1 - 1.4e-47 161.6 5.7 8.2e-47 159.1 5.8 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMG46227.1 - 1.2e-18 68.2 0.0 2.8e-18 67.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMG46227.1 - 1.2e-11 44.1 0.0 2.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMG46227.1 - 0.0028 17.4 1.2 0.0034 17.2 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMG46227.1 - 0.05 13.7 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Peptidase_S41 PF03572.18 EMG46227.1 - 0.053 13.1 0.2 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 Peptidase family S41 DUF2818 PF10993.8 EMG46227.1 - 0.13 12.8 2.7 0.2 12.3 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2818) DUF2613 PF11021.8 EMG46227.1 - 8 6.7 7.5 18 5.5 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) WD40 PF00400.32 EMG46228.1 - 8.9e-12 45.3 14.3 0.00065 20.5 0.8 6.5 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG46228.1 - 6.2e-08 32.8 7.1 0.00043 20.5 0.0 5.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMG46228.1 - 3.2e-05 23.9 2.0 0.0079 16.1 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Fungal_trans_2 PF11951.8 EMG46230.1 - 2.1e-10 40.0 0.3 3.6e-10 39.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG46230.1 - 5.8e-09 35.9 12.7 1.3e-08 34.8 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PUF PF00806.19 EMG46231.1 - 9.9e-60 195.0 19.7 1.7e-08 33.7 0.1 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EMG46231.1 - 0.0046 17.3 0.6 8.6 6.7 0.1 3.8 2 2 1 3 3 3 2 CPL (NUC119) domain Suc_Fer-like PF06999.12 EMG46232.1 - 6.2e-51 173.0 0.0 7.7e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Thioredoxin PF00085.20 EMG46233.1 - 1.3e-36 124.7 0.0 9.6e-19 67.3 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 EMG46233.1 - 2.8e-11 43.6 0.3 7.8e-07 29.3 0.0 3.5 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EMG46233.1 - 4e-11 43.3 0.0 0.0004 20.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EMG46233.1 - 2.4e-06 27.6 0.0 0.088 13.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EMG46233.1 - 6.8e-06 26.0 0.1 0.0081 16.1 0.0 2.6 2 1 0 2 2 2 2 AhpC/TSA family ERp29 PF07749.12 EMG46233.1 - 7.4e-05 23.6 0.0 0.00015 22.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain DIM1 PF02966.16 EMG46233.1 - 0.00066 19.5 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 Mitosis protein DIM1 HyaE PF07449.11 EMG46233.1 - 0.0013 18.7 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 EMG46233.1 - 0.018 14.8 0.0 0.75 9.5 0.0 2.4 2 0 0 2 2 2 0 Redoxin OST3_OST6 PF04756.13 EMG46233.1 - 0.023 14.1 0.0 0.092 12.1 0.0 1.8 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family DUF953 PF06110.11 EMG46233.1 - 0.032 13.9 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) 5_3_exonuc PF01367.20 EMG46233.1 - 0.05 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Clathrin PF00637.20 EMG46233.1 - 0.059 13.2 0.1 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS TraF PF13728.6 EMG46233.1 - 0.062 13.1 0.1 6.9 6.4 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Hyphal_reg_CWP PF11765.8 EMG46234.1 - 3.2e-100 335.3 7.1 3.2e-100 335.3 7.1 2.4 2 1 1 3 3 3 1 Hyphally regulated cell wall protein N-terminal Flocculin_t3 PF13928.6 EMG46234.1 - 7e-13 48.9 25.9 7e-13 48.9 25.9 7.7 5 1 1 6 6 6 1 Flocculin type 3 repeat Candida_ALS PF05792.13 EMG46234.1 - 1.8e-05 25.2 45.5 0.00013 22.5 16.7 9.2 7 4 3 10 10 10 3 Candida agglutinin-like (ALS) SurE PF01975.17 EMG46235.1 - 3.6e-38 131.3 0.0 6.3e-38 130.5 0.0 1.4 1 1 0 1 1 1 1 Survival protein SurE MMS1_N PF10433.9 EMG46236.1 - 3.1e-106 355.9 8.2 3.1e-106 355.9 8.2 2.2 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EMG46236.1 - 2e-66 224.5 1.1 7.7e-66 222.6 0.2 2.2 2 0 0 2 2 2 1 CPSF A subunit region Forkhead PF00250.18 EMG46237.1 - 6.4e-36 122.5 1.1 2.2e-35 120.8 1.1 2.0 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EMG46237.1 - 2.7e-07 30.8 0.2 7.7e-07 29.4 0.2 1.9 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 EMG46237.1 - 0.048 14.0 0.4 0.24 11.8 0.1 2.3 2 0 0 2 2 2 0 linker histone H1 and H5 family AIM24 PF01987.17 EMG46239.1 - 4.8e-20 72.2 0.0 6.5e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PIP5K PF01504.18 EMG46240.1 - 2.7e-94 315.4 0.1 2.7e-94 315.4 0.1 2.1 3 0 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase 2-Hacid_dh_C PF02826.19 EMG46241.1 - 5.9e-50 169.1 0.0 8.7e-50 168.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMG46241.1 - 1.7e-11 43.9 0.0 2.7e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMG46241.1 - 1e-05 25.8 0.0 2.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMG46241.1 - 0.00027 21.4 0.0 0.0007 20.1 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EMG46241.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain SURF1 PF02104.15 EMG46241.1 - 0.0042 17.4 0.0 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 SURF1 family DUF3015 PF11220.8 EMG46241.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) LRR_8 PF13855.6 EMG46242.1 - 1.3e-06 28.0 18.8 0.00041 20.0 0.0 7.7 8 4 1 9 9 9 2 Leucine rich repeat LRR_1 PF00560.33 EMG46242.1 - 0.0025 18.1 6.0 4.4 8.2 0.7 7.0 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.7 EMG46242.1 - 0.0064 16.9 28.9 0.019 15.4 0.0 9.7 9 3 3 12 12 12 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG46244.1 - 0.04 13.7 17.0 0.2 11.4 1.2 6.1 5 1 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 EMG46244.1 - 0.32 11.1 3.7 6.7 7.0 0.4 4.3 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 EMG46244.1 - 3.5 8.2 35.4 2.1 8.9 0.2 8.8 5 2 3 8 8 8 0 Leucine Rich repeats (2 copies) HMG_box PF00505.19 EMG46245.1 - 1e-16 61.1 1.3 1e-16 61.1 1.3 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMG46245.1 - 1.2e-13 51.4 0.7 1.2e-13 51.4 0.7 2.3 3 0 0 3 3 3 1 HMG-box domain DIPSY PF11763.8 EMG46245.1 - 0.059 13.5 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal DRIM PF07539.12 EMG46246.1 - 1.4e-164 548.9 5.7 1.4e-164 548.9 5.7 4.5 5 1 0 5 5 5 1 Down-regulated in metastasis DUF4042 PF13251.6 EMG46246.1 - 0.055 13.2 7.4 6 6.5 0.1 5.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) Katanin_con80 PF13925.6 EMG46246.1 - 0.35 10.9 7.8 2.2 8.3 0.2 5.0 5 0 0 5 5 5 0 con80 domain of Katanin DUF155 PF02582.14 EMG46247.1 - 4.5e-56 189.7 1.7 5.4e-56 189.5 1.0 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 EMG46247.1 - 0.002 18.5 0.6 0.13 12.8 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein family UPF0449 STE PF02200.16 EMG46248.1 - 0.0012 19.2 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor Methyltransf_23 PF13489.6 EMG46248.1 - 0.092 12.6 0.1 1.8 8.4 0.3 2.3 2 0 0 2 2 2 0 Methyltransferase domain TFIIA PF03153.13 EMG46248.1 - 0.62 10.0 30.1 0.024 14.7 21.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 EMG46249.1 - 1.2e-27 97.0 0.0 1.6e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG46249.1 - 9.1e-13 48.1 0.0 1.3e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG46249.1 - 2e-09 36.8 0.0 2e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EMG46249.1 - 0.00041 20.3 0.0 0.015 15.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Rap_GAP PF02145.15 EMG46250.1 - 0.05 13.1 0.0 0.053 13.1 0.0 1.1 1 0 0 1 1 1 0 Rap/ran-GAP Tim17 PF02466.19 EMG46252.1 - 1.4e-37 128.4 5.7 2.2e-37 127.8 5.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RGI1 PF10843.8 EMG46253.1 - 2.6e-103 343.7 6.1 3.2e-103 343.4 6.1 1.0 1 0 0 1 1 1 1 Respiratory growth induced protein 1 Bac_RepA_C PF18008.1 EMG46253.1 - 0.086 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Replication initiator protein A C-terminal domain MRG PF05712.13 EMG46254.1 - 1.9e-40 138.3 0.2 3.2e-40 137.6 0.2 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EMG46254.1 - 4.9e-10 39.2 1.3 1.2e-09 37.9 1.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RCR PF12273.8 EMG46255.1 - 9.8e-07 29.5 0.2 1.6e-06 28.8 0.2 1.3 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.6 EMG46255.1 - 0.0091 16.3 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.11 EMG46255.1 - 0.01 15.4 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family NB PF04159.13 EMG46255.1 - 0.043 13.8 0.2 0.053 13.6 0.2 1.2 1 0 0 1 1 1 0 NB glycoprotein FAM176 PF14851.6 EMG46255.1 - 0.053 13.2 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Myc_target_1 PF15179.6 EMG46255.1 - 0.086 12.7 0.3 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 Myc target protein 1 Wzy_C PF04932.15 EMG46255.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase SARAF PF06682.12 EMG46255.1 - 0.19 11.4 0.0 0.24 11.0 0.0 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis MtrG PF04210.13 EMG46255.1 - 1.9 8.4 5.0 3.4 7.6 5.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G RCR PF12273.8 EMG46256.1 - 7.8e-09 36.2 0.3 1.2e-08 35.7 0.3 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.6 EMG46256.1 - 0.029 14.6 1.2 0.049 13.9 1.1 1.4 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DAZAP2 PF11029.8 EMG46256.1 - 0.04 14.8 3.6 0.057 14.4 3.6 1.2 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) SIT PF15330.6 EMG46256.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.5 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT SARAF PF06682.12 EMG46256.1 - 0.12 12.0 0.2 0.18 11.5 0.1 1.2 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RCR PF12273.8 EMG46257.1 - 4.5e-06 27.3 11.5 2.1e-05 25.1 11.5 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4834 PF16118.5 EMG46257.1 - 0.032 15.2 0.1 0.042 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) YPEB PF14620.6 EMG46257.1 - 0.069 12.5 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 YpeB sporulation Shisa PF13908.6 EMG46257.1 - 0.083 13.1 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator OAD_gamma PF04277.13 EMG46257.1 - 0.11 13.2 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain RCR PF12273.8 EMG46258.1 - 4.7e-08 33.7 0.6 1.1e-07 32.5 0.6 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF2207 PF09972.9 EMG46258.1 - 0.059 12.1 0.0 0.072 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) InaF-motif PF15018.6 EMG46258.1 - 0.11 12.3 1.7 0.19 11.7 1.7 1.3 1 0 0 1 1 1 0 TRP-interacting helix TMEM132D_C PF15706.5 EMG46258.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Rad54_N PF08658.10 EMG46259.1 - 0.0095 16.1 1.0 0.65 10.1 1.5 2.3 2 0 0 2 2 2 1 Rad54 N terminal CrgA PF06781.12 EMG46259.1 - 0.19 11.8 0.1 0.57 10.3 0.0 1.9 2 0 0 2 2 2 0 Cell division protein CrgA DUF4637 PF15470.6 EMG46259.1 - 0.29 10.9 6.4 0.59 9.8 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) ANAPC4_WD40 PF12894.7 EMG46260.1 - 6.6e-06 26.3 0.1 0.0028 17.9 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMG46260.1 - 3.2e-05 24.6 13.3 0.051 14.5 0.1 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 EMG46260.1 - 0.0027 17.6 2.7 0.0079 16.1 0.1 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Methyltransf_8 PF05148.15 EMG46261.1 - 1.5e-64 217.9 2.0 2.1e-62 210.8 0.4 2.8 1 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EMG46261.1 - 1.1e-06 29.2 0.0 5.7e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG46261.1 - 0.00042 21.0 0.0 0.0013 19.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain RPN2_C PF18004.1 EMG46261.1 - 0.0029 17.6 11.9 0.0029 17.6 11.9 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain Methyltransf_31 PF13847.6 EMG46261.1 - 0.0048 16.7 0.1 0.013 15.3 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Trypan_PARP PF05887.11 EMG46261.1 - 0.01 15.8 5.7 0.01 15.8 5.7 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) MTS PF05175.14 EMG46261.1 - 0.12 12.0 0.0 1.1 8.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 EMG46261.1 - 0.34 10.9 4.4 0.57 10.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Zip PF02535.22 EMG46261.1 - 0.38 9.9 2.6 1.1 8.4 2.4 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter CPSF100_C PF13299.6 EMG46261.1 - 0.58 10.3 6.9 1.7 8.8 6.9 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 EMG46261.1 - 2.9 6.6 6.8 4.4 6.0 6.8 1.2 1 0 0 1 1 1 0 Presenilin DTHCT PF08070.11 EMG46261.1 - 5.1 7.9 29.6 1.5 9.6 15.5 2.9 3 0 0 3 3 3 0 DTHCT (NUC029) region Stn1 PF10451.9 EMG46262.1 - 5.8e-17 61.5 0.2 1e-16 60.7 0.2 1.3 1 0 0 1 1 1 1 Telomere regulation protein Stn1 AAA_22 PF13401.6 EMG46262.1 - 0.15 12.3 0.2 0.35 11.1 0.2 1.6 1 0 0 1 1 1 0 AAA domain Endotoxin_N PF03945.14 EMG46262.1 - 0.43 10.3 5.0 0.097 12.4 1.1 1.9 2 1 0 2 2 2 0 delta endotoxin, N-terminal domain Transthyretin PF00576.21 EMG46263.1 - 8.7e-34 116.5 0.0 1.1e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF2606 PF10794.9 EMG46263.1 - 0.032 14.0 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Herpes_DNAp_acc PF04929.12 EMG46265.1 - 0.077 12.0 1.8 0.079 11.9 1.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor HhH-GPD PF00730.25 EMG46266.1 - 5.1e-12 46.2 0.0 1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DNA_topoisoIV PF00521.20 EMG46266.1 - 0.053 12.4 0.2 0.21 10.4 0.2 2.1 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Hydrolase_4 PF12146.8 EMG46267.1 - 5.4e-14 52.0 0.0 4.8e-13 48.9 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMG46267.1 - 1.5e-10 42.1 0.0 2.1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMG46267.1 - 2.5e-06 27.3 0.8 1.6e-05 24.7 0.8 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EMG46267.1 - 1.7e-05 24.6 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 EMG46267.1 - 0.0025 17.6 0.0 0.006 16.3 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Peptidase_S9 PF00326.21 EMG46267.1 - 0.0052 16.3 0.0 0.015 14.8 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 EMG46267.1 - 0.017 14.8 0.2 0.11 12.1 0.1 2.2 2 1 0 2 2 2 0 Serine hydrolase (FSH1) DNA_pol3_delta PF06144.13 EMG46267.1 - 0.053 13.3 0.1 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit P2_N PF18628.1 EMG46267.1 - 0.096 12.4 0.0 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 Viral coat protein P2 N-terminal domain Lipase_3 PF01764.25 EMG46267.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.8 1 1 0 1 1 1 0 Lipase (class 3) BRCT PF00533.26 EMG46268.1 - 2.4e-30 104.7 2.4 9.5e-09 35.5 0.0 5.0 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EMG46268.1 - 1.5e-25 88.9 0.5 8.1e-07 28.9 0.0 5.5 5 0 0 5 5 5 5 twin BRCT domain BRCT_2 PF16589.5 EMG46268.1 - 1.3e-08 35.1 0.2 0.0034 17.7 0.0 3.8 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EMG46268.1 - 0.0023 18.2 0.1 2.1 8.7 0.0 3.7 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain PI3K_1B_p101 PF10486.9 EMG46268.1 - 0.019 12.8 6.1 0.036 11.9 6.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BRCT_3 PF18428.1 EMG46268.1 - 0.084 13.0 0.4 1.9 8.6 0.0 3.0 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain PBP1_TM PF14812.6 EMG46268.1 - 0.32 11.4 12.2 0.43 11.0 5.7 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 EMG46268.1 - 1.3 7.0 7.2 2.4 6.2 7.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 EMG46268.1 - 5.7 7.4 16.9 5.6 7.4 9.6 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain p25-alpha PF05517.12 EMG46269.1 - 0.033 14.4 0.2 0.056 13.6 0.2 1.3 1 0 0 1 1 1 0 p25-alpha V-ATPase_C PF03223.15 EMG46270.1 - 2.4e-113 379.3 8.9 2.7e-113 379.1 8.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Baculo_PEP_C PF04513.12 EMG46270.1 - 3.4 7.7 8.6 4.1 7.5 6.0 2.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SURF6 PF04935.12 EMG46271.1 - 2.6e-45 154.7 50.0 2.6e-45 154.7 50.0 2.9 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 EMG46271.1 - 3e-13 50.1 3.5 3e-13 50.1 3.5 6.8 4 1 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 PIP49_N PF14875.6 EMG46271.1 - 0.29 11.0 1.6 0.96 9.3 0.6 2.4 1 1 1 2 2 2 0 N-term cysteine-rich ER, FAM69 DUF99 PF01949.16 EMG46271.1 - 0.8 9.1 6.0 0.093 12.1 0.9 2.1 2 1 0 2 2 2 0 Protein of unknown function DUF99 TB2_DP1_HVA22 PF03134.19 EMG46272.1 - 2.6e-22 78.5 6.0 3.9e-22 78.0 6.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RSN1_7TM PF02714.15 EMG46274.1 - 7.7e-81 271.4 30.8 1.7e-80 270.3 23.8 3.1 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EMG46274.1 - 7.3e-41 139.5 2.1 7.3e-41 139.5 2.1 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EMG46274.1 - 6.3e-32 111.2 2.2 1.5e-31 110.0 2.2 1.7 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EMG46274.1 - 2.5e-26 91.7 0.3 8.7e-26 89.9 0.2 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF2615 PF11027.8 EMG46274.1 - 0.51 10.5 2.3 10 6.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) TMEM154 PF15102.6 EMG46274.1 - 3.9 7.4 5.2 0.56 10.1 0.1 2.1 2 0 0 2 2 2 0 TMEM154 protein family HECT PF00632.25 EMG46275.1 - 2.9e-93 312.7 0.0 4e-93 312.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EMG46275.1 - 7.9e-34 115.4 19.2 8.7e-12 44.9 2.4 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 EMG46275.1 - 9.5e-20 70.8 0.4 2.6e-19 69.4 0.4 1.8 1 0 0 1 1 1 1 C2 domain CDC27 PF09507.10 EMG46275.1 - 0.055 12.8 0.8 0.094 12.1 0.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ArfGap PF01412.18 EMG46276.1 - 5.5e-42 142.5 8.4 1.5e-41 141.1 3.6 2.6 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Nitr_red_assoc PF09655.10 EMG46276.1 - 0.11 13.2 2.8 0.25 12.0 0.3 2.3 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) PCI PF01399.27 EMG46277.1 - 3.4e-07 30.7 1.0 3.4e-07 30.7 1.0 3.3 2 1 0 2 2 2 1 PCI domain FeoC PF09012.10 EMG46277.1 - 0.01 15.9 0.1 0.027 14.5 0.1 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator PRD PF00874.20 EMG46277.1 - 0.018 15.3 4.0 0.042 14.1 0.3 3.1 1 1 2 3 3 3 0 PRD domain CAMSAP_CH PF11971.8 EMG46277.1 - 0.11 12.4 1.1 21 5.0 0.2 2.8 2 0 0 2 2 2 0 CAMSAP CH domain Cyt-b5 PF00173.28 EMG46278.1 - 1.6e-18 66.6 0.2 2.5e-18 66.0 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain fn3_4 PF16794.5 EMG46278.1 - 0.055 13.4 0.5 0.13 12.2 0.5 1.6 1 0 0 1 1 1 0 Fibronectin-III type domain Nop14 PF04147.12 EMG46278.1 - 0.065 11.4 12.1 0.095 10.9 12.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EMG46278.1 - 0.52 8.5 16.6 0.056 11.7 12.6 1.3 2 0 0 2 2 2 0 CDC45-like protein MRP PF09387.10 EMG46278.1 - 1.1 9.2 5.7 13 5.7 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial RNA binding protein MRP YL1 PF05764.13 EMG46278.1 - 1.1 9.3 22.9 0.12 12.5 18.7 1.4 2 0 0 2 2 2 0 YL1 nuclear protein Nop53 PF07767.11 EMG46278.1 - 1.6 8.0 17.6 0.057 12.8 11.8 1.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Orf78 PF06024.12 EMG46278.1 - 3.4 8.0 7.1 1.6 9.1 1.6 2.7 2 1 0 2 2 2 0 Orf78 (ac78) HALZ PF02183.18 EMG46282.1 - 3.5 7.9 23.3 0.038 14.2 3.5 4.7 3 2 0 3 3 3 0 Homeobox associated leucine zipper Dus PF01207.17 EMG46283.1 - 6.5e-72 242.2 0.0 7.8e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EMG46283.1 - 0.00011 21.5 0.4 0.0016 17.7 0.4 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EMG46283.1 - 0.097 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DHDPS PF00701.22 EMG46283.1 - 0.11 11.2 0.1 0.27 9.9 0.0 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family RMMBL PF07521.12 EMG46283.1 - 0.17 11.9 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Endonuclease_NS PF01223.23 EMG46284.1 - 1.1e-61 208.6 0.0 1.3e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Pacifastin_I PF05375.13 EMG46285.1 - 0.023 14.4 5.9 0.044 13.5 5.9 1.5 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) IMUP PF15761.5 EMG46285.1 - 2.5 8.8 11.2 5.3 7.8 2.8 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein HTH_Tnp_Tc5 PF03221.16 EMG46286.1 - 4.1e-14 52.4 1.5 8.3e-14 51.4 0.2 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Cofilin_ADF PF00241.20 EMG46287.1 - 1.4e-40 137.8 0.2 1.6e-40 137.7 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DnaJ PF00226.31 EMG46288.1 - 5e-25 87.4 3.8 8.5e-25 86.7 3.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EMG46288.1 - 8.7e-25 87.5 0.6 1.4e-24 86.9 0.6 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EMG46288.1 - 7.8e-13 48.6 11.4 1.6e-12 47.6 11.4 1.5 1 0 0 1 1 1 1 DnaJ central domain IceA2 PF05862.11 EMG46288.1 - 0.024 14.5 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein Cytochrome_CBB3 PF13442.6 EMG46288.1 - 0.031 14.6 1.1 0.84 10.0 0.5 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Anti-TRAP PF15777.5 EMG46288.1 - 0.073 13.0 5.7 1.1 9.2 1.1 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF3085 PF11284.8 EMG46288.1 - 0.14 12.5 0.1 0.31 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) VARLMGL PF14383.6 EMG46288.1 - 0.18 11.4 0.1 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 DUF761-associated sequence motif PHD_4 PF16866.5 EMG46288.1 - 0.36 10.9 2.9 0.49 10.5 0.1 2.5 3 0 0 3 3 3 0 PHD-finger Cytochrom_c3_2 PF14537.6 EMG46288.1 - 1.5 9.4 8.9 0.25 11.8 3.9 2.3 2 1 1 3 3 3 0 Cytochrome c3 Cytochrome_C7 PF14522.6 EMG46288.1 - 3.6 7.7 9.3 52 3.9 9.3 2.4 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-CHY PF05495.12 EMG46288.1 - 5.4 7.6 7.0 7.9 7.1 2.1 2.5 1 1 1 2 2 2 0 CHY zinc finger DUF98 PF01947.16 EMG46289.1 - 0.091 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase Env-gp36 PF09590.10 EMG46289.1 - 0.17 10.3 1.3 0.22 9.9 1.3 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein Fib_succ_major PF09603.10 EMG46290.1 - 0.0022 18.6 1.5 0.0066 17.1 1.5 1.8 1 0 0 1 1 1 1 Fibrobacter succinogenes major domain (Fib_succ_major) DUF5301 PF17225.3 EMG46290.1 - 0.0034 17.8 2.6 0.023 15.1 2.6 2.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5300) RNA_polI_A14 PF08203.11 EMG46291.1 - 4.1e-24 85.1 0.1 4.1e-24 85.1 0.1 2.2 2 1 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Med19 PF10278.9 EMG46291.1 - 0.035 14.0 14.1 0.047 13.6 14.1 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.14 EMG46291.1 - 0.042 12.1 13.5 0.038 12.3 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 EMG46291.1 - 0.045 13.5 15.2 0.058 13.1 15.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF3381 PF11861.8 EMG46291.1 - 0.049 13.4 16.7 0.062 13.1 16.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Herpes_DNAp_acc PF04929.12 EMG46291.1 - 0.074 12.0 9.1 0.08 11.9 9.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RR_TM4-6 PF06459.12 EMG46291.1 - 0.12 12.2 13.2 0.13 12.1 13.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PNISR PF15996.5 EMG46291.1 - 0.14 12.5 16.3 0.19 12.0 16.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CobT PF06213.12 EMG46291.1 - 0.75 9.1 14.9 0.88 8.9 14.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDHD PF02862.17 EMG46291.1 - 0.8 9.8 6.0 0.93 9.6 6.0 1.2 1 0 0 1 1 1 0 DDHD domain DUF4820 PF16091.5 EMG46291.1 - 1.3 8.4 8.9 1.7 7.9 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) ALMT PF11744.8 EMG46291.1 - 1.9 7.2 6.5 1.8 7.3 6.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RNA_polI_A34 PF08208.11 EMG46291.1 - 2.1 8.4 23.0 2.6 8.1 23.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RP-C_C PF11800.8 EMG46291.1 - 3 7.9 7.2 3.6 7.6 7.2 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Hid1 PF12722.7 EMG46291.1 - 3.2 5.8 9.4 2.9 5.9 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 EMG46291.1 - 3.4 6.8 7.0 3.3 6.8 7.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter dsRBD2 PF17842.1 EMG46291.1 - 6.3 7.0 7.9 3.1 8.0 5.6 1.6 1 1 1 2 2 2 0 Double-stranded RNA binding domain 2 SMC_N PF02463.19 EMG46292.1 - 1.3e-64 217.7 54.6 8.5e-63 211.7 54.6 3.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EMG46292.1 - 1.1e-22 80.5 0.0 5.2e-22 78.4 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EMG46292.1 - 2.6e-08 34.0 29.5 2.7e-05 24.2 0.5 5.4 2 2 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMG46292.1 - 3.6e-05 24.4 33.4 3.6e-05 24.4 33.4 8.1 2 2 2 4 4 1 1 AAA domain TPR_MLP1_2 PF07926.12 EMG46292.1 - 8.1e-05 22.7 18.2 8.1e-05 22.7 18.2 8.4 2 2 6 8 8 7 2 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 EMG46292.1 - 0.00023 20.9 23.2 0.00023 20.9 23.2 6.2 3 2 2 6 6 5 1 Ciliary protein causing Leber congenital amaurosis disease AAA_29 PF13555.6 EMG46292.1 - 0.00025 20.7 0.0 0.00053 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Caldesmon PF02029.15 EMG46292.1 - 0.0011 17.8 0.0 0.0011 17.8 0.0 4.0 2 1 2 4 4 3 1 Caldesmon AAA_15 PF13175.6 EMG46292.1 - 0.0032 17.2 49.8 0.0032 17.2 49.8 6.0 3 2 1 4 4 2 1 AAA ATPase domain DUF1079 PF06435.11 EMG46292.1 - 0.061 13.5 4.9 0.3 11.4 1.3 3.3 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) MtrG PF04210.13 EMG46292.1 - 5.6 6.9 22.2 4.2 7.3 0.3 6.3 5 2 1 6 6 6 0 Tetrahydromethanopterin S-methyltransferase, subunit G Mito_carr PF00153.27 EMG46293.1 - 9.7e-68 224.2 4.9 1.6e-24 85.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.11 EMG46293.1 - 0.1 12.8 1.2 1.3 9.3 0.1 2.6 2 0 0 2 2 2 0 Uperin family ACAS_N PF16177.5 EMG46293.1 - 0.31 11.0 2.8 0.59 10.1 2.8 1.4 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus Ribosomal_S6 PF01250.17 EMG46294.1 - 1.7e-24 85.9 0.0 2e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 PhoLip_ATPase_C PF16212.5 EMG46295.1 - 1.9e-69 234.2 29.0 1.9e-69 234.2 29.0 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMG46295.1 - 7.9e-16 57.5 0.4 7.9e-16 57.5 0.4 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EMG46295.1 - 3.1e-11 43.2 2.7 7.3e-11 42.0 0.0 3.1 5 0 0 5 5 5 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMG46295.1 - 7.5e-09 36.2 1.6 0.0019 18.5 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EMG46295.1 - 0.00047 19.7 1.9 0.0011 18.5 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EMG46295.1 - 0.0024 17.6 0.2 0.0024 17.6 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Neurochondrin PF05536.11 EMG46295.1 - 0.01 14.2 0.2 2.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Neurochondrin ScsC_N PF18312.1 EMG46295.1 - 1.5 8.7 3.2 50 3.8 0.0 3.3 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain RNF220 PF15926.5 EMG46295.1 - 3.1 7.4 7.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 APS_kinase PF01583.20 EMG46296.1 - 4.1e-72 241.2 0.0 5.1e-72 240.9 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EMG46296.1 - 4e-05 23.8 0.0 7.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EMG46296.1 - 0.0011 18.3 0.0 0.006 15.9 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin KTI12 PF08433.10 EMG46296.1 - 0.0057 16.1 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 EMG46296.1 - 0.0098 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EMG46296.1 - 0.029 14.9 0.0 0.071 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMG46296.1 - 0.042 14.2 0.1 0.069 13.5 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 EMG46296.1 - 0.21 10.7 0.1 0.47 9.6 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit Snf7 PF03357.21 EMG46297.1 - 2.5e-29 102.1 25.2 8.2e-29 100.4 22.3 2.2 1 1 1 2 2 2 1 Snf7 DAO PF01266.24 EMG46297.1 - 2.3e-24 86.7 0.1 1.2e-23 84.3 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Ist1 PF03398.14 EMG46297.1 - 0.00049 20.1 4.8 0.00079 19.4 4.8 1.4 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Phage_min_cap2 PF06152.11 EMG46297.1 - 0.0058 15.6 3.6 0.0058 15.6 3.6 2.1 1 1 1 2 2 2 1 Phage minor capsid protein 2 Uds1 PF15456.6 EMG46297.1 - 0.0095 16.1 0.8 0.0095 16.1 0.8 2.3 1 1 1 2 2 2 1 Up-regulated During Septation NAD_binding_8 PF13450.6 EMG46297.1 - 0.043 14.0 0.3 0.13 12.5 0.3 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMG46297.1 - 0.24 12.0 5.5 3.2 8.4 0.7 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMG46297.1 - 0.48 9.6 2.0 0.86 8.8 0.0 2.4 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase TMPIT PF07851.13 EMG46297.1 - 1.3 8.2 7.7 2 7.6 7.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 EMG46297.1 - 1.4 7.5 8.2 2.1 6.9 8.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cu-oxidase_2 PF07731.14 EMG46298.1 - 6.8e-45 152.2 10.5 7.8e-41 139.0 1.2 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMG46298.1 - 2e-43 147.2 2.0 2e-41 140.7 0.2 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EMG46298.1 - 4.3e-29 101.7 4.6 1.4e-28 100.1 0.4 3.0 3 0 0 3 3 3 1 Multicopper oxidase SKN1 PF03935.15 EMG46299.1 - 4.6e-172 572.9 5.9 5.6e-172 572.6 5.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF5305 PF17231.2 EMG46299.1 - 0.0003 20.3 0.2 0.00052 19.5 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) YukC PF10140.9 EMG46299.1 - 0.03 13.2 0.2 0.063 12.1 0.1 1.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC OAD_beta PF03977.13 EMG46299.1 - 0.066 12.2 0.1 0.095 11.7 0.1 1.1 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Orf78 PF06024.12 EMG46299.1 - 0.081 13.2 0.3 0.15 12.3 0.3 1.4 1 0 0 1 1 1 0 Orf78 (ac78) CRAL_TRIO PF00650.20 EMG46300.1 - 1.1e-36 125.9 0.0 1.8e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMG46300.1 - 1.1e-05 25.5 0.1 2.9e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EMG46300.1 - 0.00085 19.5 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 EMG46300.1 - 0.081 13.1 0.1 0.24 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) AIF-MLS PF14962.6 EMG46301.1 - 0.011 15.7 0.3 0.012 15.5 0.3 1.3 1 1 0 1 1 1 0 Mitochondria Localisation Sequence LAM_C PF12544.8 EMG46301.1 - 0.094 12.9 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 Lysine-2,3-aminomutase UQ_con PF00179.26 EMG46302.1 - 2.3e-47 160.2 0.0 2.6e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMG46302.1 - 0.00087 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EMG46302.1 - 0.061 13.2 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain EVI2A PF05399.11 EMG46303.1 - 0.018 14.6 3.2 0.018 14.6 3.2 3.0 2 1 1 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) Adaptin_binding PF10199.9 EMG46303.1 - 0.53 10.9 5.6 1.6 9.3 5.6 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 IMUP PF15761.5 EMG46303.1 - 3.8 8.2 10.7 0.25 12.1 5.4 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF2721 PF11026.8 EMG46304.1 - 0.045 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) SelP_N PF04592.14 EMG46305.1 - 0.82 9.0 13.4 0.42 10.0 8.8 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region UPF1_Zn_bind PF09416.10 EMG46307.1 - 4.8e-66 221.4 7.5 4.8e-66 221.4 7.5 3.3 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EMG46307.1 - 1.1e-58 198.1 0.1 2.9e-57 193.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EMG46307.1 - 2.1e-47 162.1 10.6 1.2e-26 94.1 0.8 2.9 2 1 1 3 3 3 2 AAA domain DUF5599 PF18141.1 EMG46307.1 - 2.7e-29 101.2 0.0 8.2e-29 99.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EMG46307.1 - 2.8e-15 56.6 0.1 2.4e-14 53.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMG46307.1 - 3.1e-13 50.3 0.1 6.7e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EMG46307.1 - 5.2e-06 26.4 0.0 0.28 10.9 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EMG46307.1 - 8.2e-05 22.0 0.0 0.0015 17.8 0.0 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EMG46307.1 - 0.00014 21.9 0.0 0.00014 21.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EMG46307.1 - 0.0015 18.4 0.0 0.0043 16.9 0.0 1.8 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 EMG46307.1 - 0.01 15.0 1.0 4.2 6.5 0.0 2.7 3 0 0 3 3 3 0 PIF1-like helicase AAA_10 PF12846.7 EMG46307.1 - 0.025 13.5 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain PhoH PF02562.16 EMG46307.1 - 0.038 13.4 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Ribosomal_S13_N PF08069.12 EMG46307.1 - 0.039 14.0 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.6 EMG46307.1 - 0.096 13.0 0.3 0.43 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 EMG46307.1 - 0.11 12.2 0.1 0.34 10.7 0.1 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase ATPase PF06745.13 EMG46307.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA PF00004.29 EMG46307.1 - 0.15 12.5 0.0 0.51 10.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MRP-L46 PF11788.8 EMG46308.1 - 3.2e-39 134.3 1.4 5.8e-39 133.5 1.4 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Blt1 PF12754.7 EMG46309.1 - 8.5e-05 22.9 0.3 0.00011 22.5 0.3 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Arrestin_C PF02752.22 EMG46309.1 - 0.024 15.1 0.7 0.046 14.2 0.7 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain EMC3_TMCO1 PF01956.16 EMG46309.1 - 0.041 13.6 0.2 0.061 13.1 0.2 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like zf-CCHC PF00098.23 EMG46310.1 - 2.4e-48 160.1 62.8 2.9e-08 33.4 0.9 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EMG46310.1 - 2.2e-12 46.5 44.1 0.017 14.8 1.4 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 EMG46310.1 - 7.1e-09 35.5 46.1 0.04 13.9 0.6 7.0 1 1 6 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 EMG46310.1 - 1.2e-06 28.1 39.4 0.044 13.5 0.8 7.1 6 1 1 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EMG46310.1 - 0.034 14.0 2.3 0.034 14.0 2.3 6.9 5 1 2 7 7 7 0 Zinc knuckle Exo_endo_phos PF03372.23 EMG46311.1 - 0.04 13.4 0.0 0.07 12.6 0.0 1.6 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family CHZ PF09649.10 EMG46311.1 - 0.13 11.8 0.2 0.3 10.6 0.2 1.6 1 0 0 1 1 1 0 Histone chaperone domain CHZ PRP9_N PF16958.5 EMG46312.1 - 1.3e-16 61.0 5.0 1.3e-16 61.0 5.0 3.8 2 2 1 3 3 3 1 Pre-mRNA-splicing factor PRP9 N-terminus DUF3449 PF11931.8 EMG46312.1 - 2.1e-08 34.2 0.6 2.1e-08 34.2 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EMG46312.1 - 4.8e-08 33.4 2.7 4.8e-08 33.4 2.7 2.8 4 0 0 4 4 4 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 EMG46312.1 - 1.9e-05 24.8 4.9 7.4e-05 22.9 4.9 2.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 EMG46312.1 - 0.0018 18.0 0.8 0.0041 16.8 0.8 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.7 EMG46312.1 - 0.044 14.2 3.2 0.044 14.2 3.2 2.4 2 1 0 2 2 2 0 Zinc-finger of C2H2 type Rsbr_N PF08678.10 EMG46312.1 - 0.18 11.9 8.6 0.67 10.0 1.7 3.7 2 1 2 4 4 4 0 Rsbr N terminal XPG_N PF00752.17 EMG46314.1 - 1.9e-25 89.3 0.0 4e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EMG46314.1 - 3.8e-23 81.6 1.5 1.1e-22 80.2 0.0 2.6 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 EMG46314.1 - 1.5e-05 25.5 0.0 5.9e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 EMG46314.1 - 0.016 14.7 0.0 0.036 13.5 0.0 1.7 1 0 0 1 1 1 0 XPG domain containing HHH_2 PF12826.7 EMG46314.1 - 0.019 15.1 0.1 0.067 13.3 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Pox_G5 PF04599.12 EMG46314.1 - 0.56 9.1 3.3 0.15 11.0 0.1 1.6 2 0 0 2 2 2 0 Poxvirus G5 protein GHMP_kinases_N PF00288.26 EMG46316.1 - 1.4e-10 41.2 0.1 3.1e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMG46316.1 - 0.002 18.5 0.0 0.0043 17.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal p450 PF00067.22 EMG46317.1 - 1.3e-89 301.0 0.0 1.6e-89 300.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HLH PF00010.26 EMG46318.1 - 1.6e-14 53.6 0.0 5.7e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRM_1 PF00076.22 EMG46319.1 - 1.9e-06 27.6 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EMG46319.1 - 4.7e-05 24.1 0.0 0.00025 21.8 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 EMG46319.1 - 0.037 14.1 0.0 0.38 10.9 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif DUF1027 PF06265.11 EMG46320.1 - 0.061 13.3 0.1 0.24 11.4 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) MAT1 PF06391.13 EMG46321.1 - 1.5e-58 198.0 31.5 1.9e-58 197.7 31.5 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EMG46321.1 - 1.7e-26 91.8 10.2 2.8e-26 91.2 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMG46321.1 - 0.0019 18.5 7.4 0.0034 17.7 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EMG46321.1 - 0.007 16.2 6.0 0.013 15.4 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMG46321.1 - 0.011 15.6 7.8 0.027 14.3 7.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMG46321.1 - 0.016 15.0 8.0 0.031 14.1 8.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2313 PF10076.9 EMG46321.1 - 0.045 13.6 3.3 0.063 13.1 0.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) zf-RING_UBOX PF13445.6 EMG46321.1 - 0.17 11.9 8.9 0.4 10.7 8.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EMG46321.1 - 0.57 10.2 8.5 2 8.4 8.5 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 EMG46321.1 - 5.8 6.8 9.0 22 5.0 9.0 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Goodbye PF17109.5 EMG46321.1 - 9 6.8 10.7 2 8.9 1.7 3.0 2 1 0 3 3 3 0 fungal STAND N-terminal Goodbye domain SAM_decarbox PF01536.16 EMG46322.1 - 9e-114 380.2 3.9 1e-113 380.0 3.9 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase RasGAP PF00616.19 EMG46323.1 - 1.5e-60 204.4 6.1 3.4e-60 203.3 6.1 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EMG46323.1 - 2.2e-05 24.7 0.1 6.6e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 C2 domain Flu_NS2 PF00601.19 EMG46323.1 - 0.095 13.0 0.3 0.35 11.2 0.3 2.0 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) Cwf_Cwc_15 PF04889.12 EMG46323.1 - 0.21 11.3 21.5 0.024 14.4 11.3 2.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNase_H2_suC PF08615.11 EMG46323.1 - 0.22 11.7 2.5 0.33 11.1 0.5 2.3 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) YL1 PF05764.13 EMG46323.1 - 0.35 10.9 9.6 0.82 9.7 9.6 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.13 EMG46323.1 - 0.55 10.1 7.8 0.58 10.0 6.0 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 EMG46323.1 - 0.94 9.9 14.4 0.6 10.5 10.5 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EF-1_beta_acid PF10587.9 EMG46323.1 - 6.3 7.3 10.3 17 5.9 10.3 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region RTC4 PF14474.6 EMG46324.1 - 7.3e-34 116.5 0.1 1.5e-33 115.5 0.1 1.5 1 0 0 1 1 1 1 RTC4-like domain Pterin_bind PF00809.22 EMG46325.1 - 5.7e-67 225.9 0.2 1.1e-62 211.9 0.0 3.3 2 1 0 2 2 2 2 Pterin binding enzyme FolB PF02152.18 EMG46325.1 - 6.8e-36 123.2 0.3 3.7e-18 66.1 0.2 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 EMG46325.1 - 8e-32 110.1 0.0 1.9e-31 108.9 0.0 1.7 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) RabGAP-TBC PF00566.18 EMG46326.1 - 7.9e-40 136.8 1.1 1.5e-39 135.9 0.1 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EnY2 PF10163.9 EMG46326.1 - 0.11 12.8 0.9 0.3 11.5 0.9 1.7 1 0 0 1 1 1 0 Transcription factor e(y)2 UPF0203 PF05254.12 EMG46326.1 - 0.21 11.8 2.3 0.3 11.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) DUF4065 PF13274.6 EMG46326.1 - 9.6 7.1 8.3 5.7 7.9 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4065) PalH PF08733.10 EMG46327.1 - 2.4e-87 293.0 21.9 3.2e-87 292.6 21.9 1.1 1 0 0 1 1 1 1 PalH/RIM21 YL1 PF05764.13 EMG46327.1 - 0.027 14.6 2.6 0.046 13.8 2.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Inv-AAD PF18785.1 EMG46328.1 - 7.9e-35 119.5 0.2 1.4e-34 118.7 0.2 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase PseudoU_synth_2 PF00849.22 EMG46328.1 - 7.9e-32 110.6 0.1 1.3e-31 109.9 0.1 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.23 EMG46328.1 - 9.1e-20 70.4 0.1 2.1e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMG46328.1 - 0.00015 21.5 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 MafB19-like deaminase NARP1 PF12569.8 EMG46329.1 - 2.3e-128 429.4 22.8 3.4e-95 319.9 3.5 3.8 2 1 2 4 4 4 3 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EMG46329.1 - 1.1e-13 50.1 25.5 0.026 14.6 0.1 10.2 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EMG46329.1 - 1.2e-11 45.1 9.8 0.01 16.4 0.0 8.0 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMG46329.1 - 1.5e-10 41.4 10.3 0.018 15.5 0.2 6.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMG46329.1 - 1.2e-09 38.2 5.7 0.1 13.4 0.0 7.8 5 1 4 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG46329.1 - 3.6e-09 36.7 24.7 0.0011 19.2 0.8 7.5 4 3 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EMG46329.1 - 1.2e-05 24.9 8.6 0.041 13.2 0.8 4.5 3 2 2 5 5 5 3 MalT-like TPR region TPR_7 PF13176.6 EMG46329.1 - 2.3e-05 24.1 6.9 2.8 8.2 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMG46329.1 - 8.5e-05 22.7 20.6 7 7.3 0.0 9.3 9 2 2 11 11 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMG46329.1 - 0.00011 21.9 29.4 0.46 10.4 0.1 9.6 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMG46329.1 - 0.00014 22.1 14.6 7.2 7.0 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EMG46329.1 - 0.0083 15.4 6.6 0.12 11.5 1.1 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMG46329.1 - 0.026 14.7 24.1 6.8 7.2 0.1 8.5 10 0 0 10 10 7 0 Tetratricopeptide repeat SNAD2 PF18745.1 EMG46329.1 - 0.087 12.5 1.2 3.5 7.3 0.0 2.7 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 2 TPR_11 PF13414.6 EMG46329.1 - 0.35 10.6 11.2 0.11 12.2 0.4 4.9 5 0 0 5 5 5 0 TPR repeat Fis1_TPR_C PF14853.6 EMG46329.1 - 0.89 9.7 12.9 5.3 7.2 0.4 4.9 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 EMG46329.1 - 1.2 9.2 7.4 3.9 7.5 0.3 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_10 PF13374.6 EMG46329.1 - 3.2 7.8 7.9 7.6 6.6 0.2 5.0 7 0 0 7 7 6 0 Tetratricopeptide repeat Got1 PF04178.12 EMG46330.1 - 4.3e-32 110.9 17.9 7e-32 110.2 17.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 EMG46330.1 - 0.008 14.5 11.4 0.01 14.2 11.4 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Sugar_tr PF00083.24 EMG46331.1 - 5.6e-27 94.7 26.0 7.4e-20 71.2 11.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMG46331.1 - 1.8e-15 56.8 41.1 2.1e-07 30.2 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 EMG46331.1 - 0.07 13.4 7.1 0.24 11.7 0.0 4.2 3 0 0 3 3 3 0 Transglycosylase associated protein DUF4571 PF15137.6 EMG46333.1 - 0.032 13.9 0.8 0.071 12.7 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) DUF4407 PF14362.6 EMG46333.1 - 0.19 11.0 1.5 0.33 10.3 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IFP_35_N PF07334.13 EMG46333.1 - 0.22 11.6 3.6 0.61 10.2 3.6 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Striatin PF08232.12 EMG46333.1 - 6.5 7.3 11.5 0.2 12.2 3.6 2.5 3 0 0 3 3 3 0 Striatin family Sugar_tr PF00083.24 EMG46334.1 - 1.1e-23 83.8 36.9 6.2e-15 55.0 16.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMG46334.1 - 3.6e-16 59.0 47.0 6.3e-08 31.9 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 EMG46334.1 - 0.19 12.0 0.0 0.19 12.0 0.0 4.7 4 0 0 4 4 4 0 Transglycosylase associated protein COPIIcoated_ERV PF07970.12 EMG46335.1 - 1.2e-72 244.4 0.2 1.4e-72 244.1 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EMG46335.1 - 1e-27 96.3 2.1 1.9e-27 95.4 1.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sugar_tr PF00083.24 EMG46336.1 - 4.9e-14 52.0 9.3 5.8e-14 51.8 9.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG46336.1 - 2.5e-10 39.8 12.1 3.3e-10 39.4 12.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.32 EMG46337.1 - 1.8e-12 47.6 11.9 3.8e-05 24.4 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG46337.1 - 1.6e-11 44.3 0.1 0.078 13.3 0.0 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain SdiA-regulated PF06977.11 EMG46337.1 - 0.0017 17.7 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 SdiA-regulated Peptidase_S24 PF00717.23 EMG46338.1 - 1.6e-09 37.6 0.2 3.2e-09 36.6 0.2 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EMG46338.1 - 1.2e-05 25.2 0.0 0.017 14.9 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 CBFD_NFYB_HMF PF00808.23 EMG46339.1 - 1.1e-18 67.3 0.6 1.1e-18 67.3 0.6 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMG46339.1 - 9.3e-16 58.4 0.4 9.3e-16 58.4 0.4 3.3 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 SET PF00856.28 EMG46339.1 - 3e-14 53.8 0.1 3e-14 53.8 0.1 3.3 2 1 0 2 2 2 1 SET domain SAF PF08666.12 EMG46339.1 - 0.028 15.1 0.1 24 5.7 0.0 3.1 4 0 0 4 4 4 0 SAF domain CENP-X PF09415.10 EMG46339.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.2 2 0 0 2 2 2 0 CENP-S associating Centromere protein X C1_1 PF00130.22 EMG46339.1 - 0.64 9.9 10.5 0.019 14.8 3.1 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CDK5_activator PF03261.15 EMG46339.1 - 3.4 7.1 27.1 0.8 9.2 12.2 2.5 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein PBP PF01161.20 EMG46340.1 - 2.1e-24 86.3 0.1 2.8e-24 85.9 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DIM1 PF02966.16 EMG46341.1 - 2.3e-64 215.1 0.2 2.6e-64 215.0 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EMG46341.1 - 0.074 13.0 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 EMG46341.1 - 0.12 12.7 0.4 0.2 12.0 0.4 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.20 EMG46342.1 - 1.2e-18 66.9 0.2 1.5e-18 66.6 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMG46342.1 - 4e-05 24.0 0.2 0.00014 22.3 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMG46342.1 - 0.00026 21.2 0.1 0.012 15.9 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_5 PF13743.6 EMG46342.1 - 0.0015 18.3 0.1 0.0019 17.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 EMG46342.1 - 0.0027 17.7 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 EMG46342.1 - 0.0034 16.8 0.0 0.0035 16.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF836 PF05768.14 EMG46342.1 - 0.0039 17.6 0.2 0.0059 17.0 0.2 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DIM1 PF02966.16 EMG46342.1 - 0.0071 16.1 0.3 0.0081 15.9 0.3 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 HyaE PF07449.11 EMG46342.1 - 0.0084 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EMG46342.1 - 0.015 15.2 0.3 0.34 10.8 0.1 2.0 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 EMG46342.1 - 0.062 13.1 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Amidohydro_1 PF01979.20 EMG46343.1 - 7.5e-07 28.8 0.0 3.2e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 EMG46343.1 - 1.9e-06 27.9 0.0 3.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Ribosomal_L19 PF01245.20 EMG46344.1 - 1.2e-08 34.9 1.0 2.8e-08 33.7 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L19 Peptidase_S77 PF03420.13 EMG46344.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Prohead core protein serine protease CFEM PF05730.11 EMG46345.1 - 0.0016 18.5 5.0 0.0025 17.9 5.0 1.3 1 0 0 1 1 1 1 CFEM domain SPX PF03105.19 EMG46347.1 - 7.5e-45 154.5 13.9 1.3e-44 153.8 13.9 1.4 1 0 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EMG46347.1 - 5e-09 35.9 7.1 9.8e-09 35.0 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMG46347.1 - 3.4e-08 33.5 8.7 3.4e-08 33.5 8.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EMG46347.1 - 5.8e-08 32.9 8.2 1.2e-07 31.9 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMG46347.1 - 2.7e-07 30.3 8.7 5.7e-07 29.3 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMG46347.1 - 5.5e-07 29.4 8.5 5.5e-07 29.4 8.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG46347.1 - 9.6e-07 28.7 6.4 2.2e-06 27.5 6.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EMG46347.1 - 1.3e-06 28.1 8.5 9.5e-06 25.4 8.8 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EMG46347.1 - 9.1e-06 25.5 7.5 2.6e-05 24.1 7.6 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EMG46347.1 - 0.0035 17.1 7.2 0.016 15.0 7.2 2.1 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain HsdM_N PF12161.8 EMG46347.1 - 0.0049 17.5 6.8 0.016 15.8 6.8 1.9 1 0 0 1 1 1 1 HsdM N-terminal domain zf-rbx1 PF12678.7 EMG46347.1 - 0.029 14.6 5.7 0.088 13.1 5.7 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EMG46347.1 - 0.031 14.4 4.0 0.11 12.6 4.0 2.0 1 0 0 1 1 1 0 zinc RING finger of MSL2 TerY_C PF15616.6 EMG46347.1 - 0.58 10.3 7.6 0.19 11.8 1.5 2.8 1 1 2 3 3 3 0 TerY-C metal binding domain WBS_methylT PF12589.8 EMG46348.1 - 3.1e-12 47.1 6.2 5.2e-12 46.4 6.2 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EMG46348.1 - 7.2e-12 45.8 0.0 1.5e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG46348.1 - 2.5e-09 37.7 0.0 7.3e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG46348.1 - 9.9e-07 29.4 0.1 2.9e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMG46348.1 - 5.3e-05 23.1 0.0 8.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EMG46348.1 - 0.0003 21.1 0.0 0.0007 19.9 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase CMAS PF02353.20 EMG46348.1 - 0.0049 16.2 0.0 0.052 12.8 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EMG46348.1 - 0.025 14.4 0.0 0.073 12.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EMG46348.1 - 0.077 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EMG46348.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EMG46348.1 - 0.13 12.2 0.1 3.8 7.5 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Bin3 PF06859.12 EMG46348.1 - 0.14 12.8 0.2 0.83 10.3 0.2 2.3 1 1 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) GidB PF02527.15 EMG46348.1 - 0.14 11.4 0.1 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Myosin_head PF00063.21 EMG46349.1 - 1.3e-257 856.4 20.2 1.3e-257 856.4 20.2 3.7 3 1 0 3 3 3 1 Myosin head (motor domain) APG6_N PF17675.1 EMG46349.1 - 0.011 16.3 22.3 0.011 16.3 22.3 11.7 3 2 9 12 12 12 0 Apg6 coiled-coil region AAA_22 PF13401.6 EMG46349.1 - 0.014 15.7 0.0 0.23 11.8 0.0 3.2 1 0 0 1 1 1 0 AAA domain Myosin_N PF02736.19 EMG46349.1 - 0.017 15.0 0.7 0.038 13.8 0.0 2.0 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 EMG46349.1 - 0.019 15.4 0.0 0.13 12.6 0.0 2.5 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_M16 PF00675.20 EMG46350.1 - 2.2e-34 118.6 0.0 3.9e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMG46350.1 - 5.4e-32 111.3 0.0 1.7e-31 109.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Gal4_dimer PF03902.13 EMG46350.1 - 0.0099 16.0 0.1 0.022 14.9 0.1 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain TRPM_tetra PF16519.5 EMG46350.1 - 0.2 11.8 2.7 0.24 11.5 0.3 2.2 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF3112 PF11309.8 EMG46351.1 - 1.1e-95 319.2 3.3 1.1e-95 319.2 3.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) Cyclin_N PF00134.23 EMG46352.1 - 6.6e-41 139.0 3.1 5.3e-40 136.1 0.5 2.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EMG46352.1 - 3.6e-09 36.7 0.1 1.4e-08 34.9 0.1 2.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain Recep_L_domain PF01030.24 EMG46352.1 - 0.034 14.3 2.6 0.11 12.6 2.6 1.9 1 0 0 1 1 1 0 Receptor L domain RXT2_N PF08595.11 EMG46352.1 - 0.2 11.7 12.7 0.099 12.7 1.1 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Oxysterol_BP PF01237.18 EMG46353.1 - 3.4e-89 299.3 5.0 1e-80 271.4 0.1 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DUF3391 PF11871.8 EMG46353.1 - 0.0073 16.9 0.5 3.7 8.1 0.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3391) PI3_PI4_kinase PF00454.27 EMG46354.1 - 4.5e-33 115.1 0.1 1.2e-30 107.1 0.0 3.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 EMG46354.1 - 4.4e-16 58.6 2.1 7.3e-16 57.9 0.5 2.4 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 EMG46354.1 - 1.9e-06 27.4 1.3 1.9e-06 27.4 1.3 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EMG46354.1 - 0.03 13.6 0.2 0.098 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) PAP_central PF04928.17 EMG46355.1 - 1.2e-109 365.1 0.0 1.7e-109 364.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EMG46355.1 - 1.7e-49 167.7 0.2 3e-49 166.9 0.2 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EMG46355.1 - 2e-13 50.4 0.0 5.9e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EMG46355.1 - 0.012 15.7 0.1 0.048 13.8 0.0 2.0 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 EMG46355.1 - 0.027 14.2 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Sec10 PF07393.11 EMG46357.1 - 8.1e-70 236.1 28.0 1.2e-69 235.6 28.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 EMG46357.1 - 1.8e-05 24.5 0.4 5.3e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 F-box domain ECH_2 PF16113.5 EMG46357.1 - 0.049 13.1 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase F-box-like PF12937.7 EMG46357.1 - 0.063 13.2 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 F-box-like Cpn60_TCP1 PF00118.24 EMG46359.1 - 1.2e-159 532.1 1.9 1.4e-159 531.9 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 EMG46359.1 - 0.14 12.6 0.1 0.49 10.9 0.1 1.9 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch RVT_1 PF00078.27 EMG46360.1 - 8.8e-31 107.1 0.1 1.5e-30 106.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 EMG46360.1 - 3.9e-26 91.4 0.0 8.6e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EMG46360.1 - 9.4e-25 86.6 0.1 3.8e-24 84.6 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 EMG46361.1 - 5e-11 42.8 0.0 8.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain BSD PF03909.17 EMG46361.1 - 0.081 12.9 0.5 0.28 11.2 0.5 1.9 1 0 0 1 1 1 0 BSD domain RE_HindVP PF09519.10 EMG46361.1 - 0.15 11.0 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 HindVP restriction endonuclease AA_permease PF00324.21 EMG46362.1 - 5.7e-137 457.2 38.1 6.4e-137 457.0 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG46362.1 - 8.4e-45 153.4 42.5 1e-44 153.1 42.5 1.0 1 0 0 1 1 1 1 Amino acid permease Homeodomain PF00046.29 EMG46363.1 - 3.9e-05 23.4 3.8 9.6e-05 22.2 3.8 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EMG46363.1 - 0.00019 21.3 0.8 0.00019 21.3 0.8 2.2 3 0 0 3 3 3 1 Homeobox KN domain GDPD PF03009.17 EMG46363.1 - 0.0097 15.7 3.5 0.011 15.4 3.2 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PTPS PF01242.19 EMG46363.1 - 0.018 15.0 0.8 0.038 14.0 0.8 1.4 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Cas_Cmr5 PF09701.10 EMG46363.1 - 0.16 12.3 2.3 0.58 10.5 2.0 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) Fungal_trans PF04082.18 EMG46364.1 - 4.4e-20 71.8 2.8 4.4e-20 71.8 2.8 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG46364.1 - 1.6e-07 31.3 11.2 3.4e-07 30.3 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Use1 PF09753.9 EMG46364.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 Zn_clus PF00172.18 EMG46366.1 - 1.5e-10 41.0 13.0 2.9e-10 40.1 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUV3_C PF12513.8 EMG46366.1 - 0.096 12.6 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal TPR_1 PF00515.28 EMG46367.1 - 7.7e-48 158.5 28.3 3e-09 36.3 2.1 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 EMG46367.1 - 1e-38 128.3 28.6 6.3e-08 32.1 1.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 EMG46367.1 - 1.1e-37 127.7 7.0 1.8e-22 79.0 0.3 3.0 3 0 0 3 3 3 2 STI1 domain TPR_8 PF13181.6 EMG46367.1 - 7.2e-22 75.7 28.7 7.6e-07 28.9 0.5 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 EMG46367.1 - 3.5e-21 74.6 22.2 0.0033 17.1 0.1 8.3 6 2 2 8 8 8 6 TPR repeat TPR_16 PF13432.6 EMG46367.1 - 1.1e-19 70.8 9.8 7.7e-06 26.5 0.5 5.9 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EMG46367.1 - 1.1e-18 66.4 7.3 0.0075 17.0 0.0 7.9 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 EMG46367.1 - 1.1e-17 64.1 16.7 3.2e-08 33.7 0.9 5.8 3 3 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMG46367.1 - 9.7e-16 58.0 19.4 0.00034 21.1 2.0 6.7 4 3 3 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMG46367.1 - 1.4e-14 52.9 7.6 0.012 15.6 0.1 7.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMG46367.1 - 1.7e-14 53.0 17.2 0.18 12.2 0.1 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 EMG46367.1 - 8.9e-12 44.5 14.0 0.0054 16.6 0.2 6.7 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EMG46367.1 - 4.2e-11 42.8 0.9 0.00027 21.0 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EMG46367.1 - 5.4e-07 29.8 19.2 1 10.1 0.1 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMG46367.1 - 9.6e-06 25.6 7.9 3.7e-05 23.7 0.2 4.6 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EMG46367.1 - 0.0024 18.1 14.7 0.13 12.5 0.6 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.9 EMG46367.1 - 0.046 12.5 3.1 0.05 12.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) DUF5486 PF17588.2 EMG46367.1 - 0.11 12.3 1.9 0.21 11.5 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5486) PPR_2 PF13041.6 EMG46367.1 - 0.2 11.9 0.4 1.4e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 PPR repeat family BTAD PF03704.17 EMG46367.1 - 0.36 11.3 10.6 4.6 7.7 0.1 4.5 3 1 2 5 5 5 0 Bacterial transcriptional activator domain DUF913 PF06025.12 EMG46367.1 - 0.36 9.7 2.7 3.5 6.5 4.5 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Alkyl_sulf_dimr PF14863.6 EMG46367.1 - 1.9 9.0 6.4 1.6 9.2 0.1 3.7 3 2 0 4 4 3 0 Alkyl sulfatase dimerisation DUF357 PF04010.13 EMG46367.1 - 6.2 7.0 12.7 3.1 7.9 0.2 4.8 3 2 1 5 5 5 0 Protein of unknown function (DUF357) TPR_3 PF07720.12 EMG46367.1 - 6.2 6.9 21.0 6.6 6.8 0.2 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat bZIP_1 PF00170.21 EMG46368.1 - 0.0001 22.3 14.1 0.0001 22.3 14.1 3.3 4 0 0 4 4 4 1 bZIP transcription factor TF_AP-2 PF03299.14 EMG46368.1 - 0.068 13.1 2.9 0.12 12.3 2.9 1.4 1 0 0 1 1 1 0 Transcription factor AP-2 bZIP_Maf PF03131.17 EMG46368.1 - 0.37 11.3 13.2 0.27 11.8 11.0 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor RHH_4 PF13467.6 EMG46369.1 - 0.0093 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Ribbon-helix-helix domain ComA PF02679.15 EMG46369.1 - 0.066 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) BBS1 PF14779.6 EMG46369.1 - 0.08 12.4 0.3 0.15 11.5 0.3 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Zn_clus PF00172.18 EMG46370.1 - 3.8e-09 36.5 15.2 7e-09 35.7 15.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMG46370.1 - 0.0001 21.4 1.1 0.00018 20.6 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_phi PF04931.13 EMG46370.1 - 0.0022 16.2 11.2 0.0035 15.5 11.2 1.2 1 0 0 1 1 1 1 DNA polymerase phi Osteopontin PF00865.18 EMG46370.1 - 0.13 11.7 14.6 0.21 11.1 14.6 1.3 1 0 0 1 1 1 0 Osteopontin Cwf_Cwc_15 PF04889.12 EMG46370.1 - 3 7.5 13.4 5.1 6.8 13.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAD_binding_8 PF08022.12 EMG46371.1 - 7.1e-26 90.4 0.1 1.3e-25 89.6 0.1 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EMG46371.1 - 2.1e-25 89.7 0.0 3.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EMG46371.1 - 3.1e-22 79.0 13.7 3.1e-22 79.0 13.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component CFEM PF05730.11 EMG46371.1 - 2.8 8.1 7.5 5 7.3 7.5 1.3 1 0 0 1 1 1 0 CFEM domain ETF_QO PF05187.13 EMG46372.1 - 1.1e-46 157.2 1.4 2.2e-46 156.3 0.5 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 EMG46372.1 - 3e-08 33.2 0.1 0.0013 17.9 0.4 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EMG46372.1 - 1.9e-07 31.0 0.0 2.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMG46372.1 - 5.6e-07 29.0 0.0 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 EMG46372.1 - 3.6e-05 23.1 0.0 0.00071 18.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMG46372.1 - 6.7e-05 23.0 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMG46372.1 - 0.00016 20.5 0.3 0.0044 15.8 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EMG46372.1 - 0.00031 20.1 0.1 0.00083 18.7 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMG46372.1 - 0.0071 15.6 0.2 0.0071 15.6 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMG46372.1 - 0.018 15.6 0.4 3.3 8.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMG46372.1 - 0.033 14.2 0.1 0.07 13.1 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 EMG46372.1 - 0.036 13.2 0.0 0.076 12.1 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_7 PF12838.7 EMG46372.1 - 0.038 14.6 0.5 0.088 13.4 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 EMG46372.1 - 0.079 12.0 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_2 PF12797.7 EMG46372.1 - 0.11 12.6 0.5 0.33 11.1 0.5 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain CDC24 PF06395.11 EMG46373.1 - 3.9e-35 120.0 0.6 3.9e-35 120.0 0.6 2.2 2 0 0 2 2 2 1 CDC24 Calponin PH_10 PF15411.6 EMG46373.1 - 4.6e-31 107.6 0.1 1.2e-30 106.3 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EMG46373.1 - 1.3e-30 107.0 0.9 1.3e-30 107.0 0.9 2.1 2 0 0 2 2 2 1 RhoGEF domain PB1 PF00564.24 EMG46373.1 - 1.2e-06 28.4 0.2 3.6e-06 26.8 0.2 1.8 1 0 0 1 1 1 1 PB1 domain DASH_Dad4 PF08650.10 EMG46373.1 - 0.034 14.1 0.3 1.3 9.0 0.1 3.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 EF-hand_6 PF13405.6 EMG46374.1 - 0.0002 21.0 0.0 0.014 15.3 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EMG46374.1 - 0.00057 20.3 0.2 0.0015 18.9 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EMG46374.1 - 0.034 13.7 0.0 0.5 10.0 0.0 2.6 2 0 0 2 2 2 0 EF hand LRR_8 PF13855.6 EMG46375.1 - 1.5e-11 43.9 24.4 3e-05 23.7 0.2 5.5 6 0 0 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 EMG46375.1 - 1.1e-09 38.4 37.7 0.0063 16.9 0.3 7.7 8 1 1 9 9 9 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EMG46375.1 - 0.093 12.6 0.2 0.24 11.3 0.2 1.7 1 0 0 1 1 1 0 F-box-like FNIP PF05725.12 EMG46375.1 - 0.12 12.5 0.1 0.12 12.5 0.1 6.6 8 0 0 8 8 8 0 FNIP Repeat Pex24p PF06398.11 EMG46376.1 - 1e-52 179.3 18.0 1.6e-52 178.8 18.0 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Noelin-1 PF12308.8 EMG46376.1 - 0.14 12.2 2.1 0.4 10.7 1.6 2.0 1 1 0 1 1 1 0 Neurogenesis glycoprotein Gti1_Pac2 PF09729.9 EMG46376.1 - 0.8 9.8 10.6 0.16 12.1 6.6 1.8 2 0 0 2 2 2 0 Gti1/Pac2 family SIR2 PF02146.17 EMG46377.1 - 1.3e-37 129.5 0.0 3e-35 121.7 0.0 3.1 2 1 0 2 2 2 1 Sir2 family BLOC1_2 PF10046.9 EMG46377.1 - 0.037 14.3 0.6 0.34 11.2 0.1 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3716 PF12511.8 EMG46377.1 - 0.048 13.7 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) CHB_HEX PF03173.13 EMG46377.1 - 0.063 12.9 0.0 0.25 11.0 0.0 1.9 2 1 0 2 2 2 0 Putative carbohydrate binding domain Pkinase PF00069.25 EMG46378.1 - 9.2e-75 251.4 0.0 1.4e-74 250.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG46378.1 - 1.6e-37 129.2 0.0 2.4e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EMG46378.1 - 3.4e-33 114.6 2.1 1.2e-27 96.7 0.3 3.1 1 1 1 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EMG46378.1 - 5.3e-22 77.7 4.2 5.9e-22 77.5 2.1 2.1 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EMG46378.1 - 2.6e-08 33.5 0.0 4.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EMG46378.1 - 3.7e-05 23.4 0.1 7.2e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.9 EMG46378.1 - 0.00029 19.8 0.2 0.00045 19.2 0.2 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 EMG46378.1 - 0.0011 18.0 0.4 0.0022 17.0 0.4 1.5 1 1 0 1 1 1 1 Haspin like kinase domain UBA_3 PF09288.10 EMG46378.1 - 0.0062 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Kdo PF06293.14 EMG46378.1 - 0.0082 15.5 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2443 PF10398.9 EMG46378.1 - 0.036 14.1 0.7 0.093 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) DUF1917 PF08939.10 EMG46378.1 - 1.6 8.5 0.0 1.6 8.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) SelP_N PF04592.14 EMG46378.1 - 3.9 6.8 22.0 6.4 6.1 22.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3347 PF11827.8 EMG46378.1 - 4.7 7.4 5.6 18 5.5 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Cyclin_N PF00134.23 EMG46379.1 - 5e-34 116.8 0.5 7.7e-34 116.2 0.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cupin_8 PF13621.6 EMG46380.1 - 1.3e-38 133.1 0.0 3.8e-38 131.7 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EMG46380.1 - 3.4e-07 30.1 0.0 3.4e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 Cupin superfamily protein RPA43_OB PF17875.1 EMG46380.1 - 0.086 13.5 3.2 0.61 10.7 1.4 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Cupin_2 PF07883.11 EMG46380.1 - 0.14 11.9 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Cupin domain OTU PF02338.19 EMG46381.1 - 2.7e-24 86.1 0.7 9.2e-24 84.4 0.0 2.1 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EMG46381.1 - 2.7e-05 23.8 0.3 2.7e-05 23.8 0.3 2.1 2 1 0 2 2 2 1 Peptidase C65 Otubain RNA_pol_Rpb2_6 PF00562.28 EMG46381.1 - 0.0081 15.3 4.8 0.009 15.1 4.8 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 DUF883 PF05957.13 EMG46381.1 - 2.2 8.9 10.3 31 5.3 1.8 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) FapA PF03961.13 EMG46381.1 - 4.6 5.8 15.2 7.2 5.1 15.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A YABBY PF04690.13 EMG46381.1 - 5.1 7.6 7.6 9.1 6.8 7.6 1.5 1 0 0 1 1 1 0 YABBY protein Herpes_IE1 PF07340.11 EMG46382.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Erf4 PF10256.9 EMG46383.1 - 9.6e-32 109.5 0.1 1.8e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family PPR_2 PF13041.6 EMG46384.1 - 3e-05 24.1 12.0 0.069 13.4 0.1 6.0 7 0 0 7 7 7 2 PPR repeat family PPR_3 PF13812.6 EMG46384.1 - 6.2e-05 23.0 11.2 0.026 14.6 0.2 4.8 6 0 0 6 6 6 2 Pentatricopeptide repeat domain YfiO PF13525.6 EMG46384.1 - 0.00018 21.3 4.3 0.015 15.0 0.0 2.6 2 0 0 2 2 2 2 Outer membrane lipoprotein PPR PF01535.20 EMG46384.1 - 0.00066 19.7 12.7 2.7 8.4 0.0 6.6 8 0 0 8 8 8 2 PPR repeat ATP13 PF12921.7 EMG46384.1 - 0.0019 18.1 1.3 0.12 12.3 0.4 3.4 2 1 1 3 3 3 1 Mitochondrial ATPase expression TPR_6 PF13174.6 EMG46384.1 - 0.015 15.9 4.8 0.31 11.8 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMG46384.1 - 0.017 15.9 0.0 8.1 7.6 0.0 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat SPOB_a PF14689.6 EMG46384.1 - 0.021 14.5 2.4 0.98 9.2 0.0 3.6 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_19 PF14559.6 EMG46384.1 - 0.023 15.2 0.9 0.16 12.5 0.0 2.9 4 0 0 4 4 3 0 Tetratricopeptide repeat PknG_TPR PF16918.5 EMG46384.1 - 0.059 12.1 0.0 0.099 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TPR_8 PF13181.6 EMG46384.1 - 0.061 13.6 1.9 20 5.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_long PF17177.4 EMG46384.1 - 0.084 12.2 0.1 0.41 10.0 0.0 2.2 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP DUF1493 PF07377.12 EMG46384.1 - 1.2 9.6 4.3 5.7 7.5 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1493) Cyto_heme_lyase PF01265.17 EMG46385.1 - 1.3e-98 330.2 4.9 4.6e-98 328.4 4.9 1.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Dynamin_M PF01031.20 EMG46386.1 - 1.8e-99 332.6 0.5 4.8e-99 331.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EMG46386.1 - 3.8e-55 186.5 0.1 7.2e-55 185.6 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EMG46386.1 - 1.1e-28 99.2 4.7 1.1e-28 99.2 4.7 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EMG46386.1 - 0.00012 22.1 0.2 0.00042 20.4 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Macro PF01661.21 EMG46387.1 - 2.8e-27 95.1 0.0 3.3e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Macro domain TruB_N PF01509.18 EMG46389.1 - 3.7e-44 150.7 0.1 1.6e-43 148.6 0.1 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EMG46389.1 - 2.2e-05 24.5 0.0 5.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PseudoU_synth_2 PF00849.22 EMG46389.1 - 0.096 12.8 0.2 0.15 12.1 0.2 1.5 1 1 0 1 1 1 0 RNA pseudouridylate synthase Aldose_epim PF01263.20 EMG46390.1 - 6.9e-43 147.1 0.2 8.9e-43 146.7 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Msap1 PF17077.5 EMG46391.1 - 7.7e-05 22.0 15.6 0.00042 19.6 15.5 1.9 1 1 0 1 1 1 1 Mitotic spindle associated protein SHE1 PAP2_3 PF14378.6 EMG46393.1 - 1.9e-22 79.9 11.1 1.9e-22 79.9 11.1 2.1 1 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EMG46393.1 - 7e-11 42.0 3.1 7e-11 42.0 3.1 2.2 2 0 0 2 2 2 1 PAP2 superfamily POLO_box PF00659.18 EMG46394.1 - 0.1 12.8 0.1 0.38 11.0 0.1 2.1 1 1 1 2 2 2 0 POLO box duplicated region SPX PF03105.19 EMG46395.1 - 9.6 6.0 9.4 14 5.5 9.4 1.1 1 0 0 1 1 1 0 SPX domain Flocculin_t3 PF13928.6 EMG46396.1 - 0.2 12.2 39.8 2.2 8.8 29.5 3.7 1 1 1 2 2 2 0 Flocculin type 3 repeat MFS_1 PF07690.16 EMG46397.1 - 1.3e-31 109.8 17.9 1.5e-31 109.6 17.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG46397.1 - 5.1e-13 48.7 15.8 6.9e-13 48.3 15.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EMG46397.1 - 1.4e-05 23.7 7.6 1.7e-05 23.5 7.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EMG46397.1 - 0.44 8.8 6.8 0.06 11.6 2.0 1.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family LRR_4 PF12799.7 EMG46398.1 - 2.2e-08 34.3 1.6 2.2e-08 34.3 1.6 11.4 8 3 2 10 10 10 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG46398.1 - 3.2e-08 33.2 7.7 3.2e-08 33.2 7.7 8.6 8 1 3 11 11 11 2 Leucine rich repeat LRR_6 PF13516.6 EMG46398.1 - 0.0016 18.3 23.3 0.24 11.6 0.0 7.6 7 0 0 7 7 7 3 Leucine Rich repeat CBP_BcsR PF10945.8 EMG46398.1 - 0.073 12.6 0.3 11 5.6 0.3 3.4 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR LRR_1 PF00560.33 EMG46398.1 - 8.8 7.3 36.2 2 9.3 0.5 9.0 9 3 0 9 9 9 0 Leucine Rich Repeat GPR_Gpa2_C PF11970.8 EMG46399.1 - 9.6e-36 121.7 2.8 2.1e-35 120.6 2.8 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Git3 PF11710.8 EMG46399.1 - 4.7e-11 42.9 3.9 8.6e-11 42.0 3.9 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 FAM176 PF14851.6 EMG46399.1 - 0.028 14.1 3.8 0.067 12.9 3.8 1.6 1 0 0 1 1 1 0 FAM176 family Peptidase_S68 PF10461.9 EMG46400.1 - 0.07 13.3 0.1 0.07 13.3 0.1 1.7 2 0 0 2 2 2 0 Peptidase S68 YTH PF04146.15 EMG46401.1 - 9.9e-35 119.9 0.1 2.2e-34 118.8 0.1 1.6 1 0 0 1 1 1 1 YT521-B-like domain COQ7 PF03232.13 EMG46402.1 - 1.8e-76 255.7 0.1 2.2e-76 255.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EMG46402.1 - 0.0037 17.7 0.1 0.018 15.4 0.0 2.0 2 0 0 2 2 2 1 Rubrerythrin Pup PF05639.11 EMG46402.1 - 0.064 14.2 1.3 0.14 13.1 1.3 1.5 1 0 0 1 1 1 0 Pup-like protein Nefa_Nip30_N PF10187.9 EMG46402.1 - 0.095 13.1 0.7 0.095 13.1 0.7 1.7 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 HSCB_C PF07743.13 EMG46402.1 - 0.1 13.1 0.6 0.19 12.2 0.6 1.4 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Nuf2 PF03800.14 EMG46403.1 - 6.6e-44 149.4 0.0 6.6e-44 149.4 0.0 2.4 2 1 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 EMG46403.1 - 2.9e-16 59.6 15.7 2.9e-16 59.6 15.7 5.1 1 1 4 5 5 5 2 Designed helical repeat protein 10 domain HIP1_clath_bdg PF16515.5 EMG46403.1 - 0.015 15.9 4.0 0.015 15.9 4.0 4.7 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cyclin_C PF02984.19 EMG46403.1 - 0.16 12.0 2.1 0.3 11.2 0.2 2.4 1 1 1 2 2 2 0 Cyclin, C-terminal domain DUF5481 PF17578.2 EMG46403.1 - 0.38 11.2 2.6 0.45 11.0 0.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5481) Spc7 PF08317.11 EMG46403.1 - 1.8 7.3 57.0 0.029 13.3 20.1 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 EMG46403.1 - 5.8 6.2 60.5 1 8.7 23.6 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Rsbr_N PF08678.10 EMG46404.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Rsbr N terminal PseudoU_synth_1 PF01416.20 EMG46405.1 - 2e-35 121.5 0.0 7.9e-32 109.9 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase TIMELESS PF04821.14 EMG46406.1 - 3.4e-83 279.1 2.7 3.4e-83 279.1 2.7 2.9 3 0 0 3 3 3 2 Timeless protein Aa_trans PF01490.18 EMG46407.1 - 6.5e-29 100.9 13.0 8.2e-29 100.5 13.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PWI PF01480.17 EMG46407.1 - 1.8e-14 53.8 0.1 3.6e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 PWI domain Trp_Tyr_perm PF03222.13 EMG46407.1 - 0.001 18.2 7.7 0.0014 17.7 7.7 1.2 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family TMEM247 PF15444.6 EMG46407.1 - 0.0032 17.6 0.8 0.0052 16.9 0.8 1.2 1 0 0 1 1 1 1 Transmembrane protein 247 Sdh_cyt PF01127.22 EMG46407.1 - 0.027 14.5 3.0 1 9.4 1.2 2.3 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Y_phosphatase3 PF13350.6 EMG46408.1 - 4.6e-58 196.9 0.0 6.9e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Abhydrolase_1 PF00561.20 EMG46408.1 - 1.2e-06 28.3 0.1 0.0024 17.6 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG46408.1 - 7.9e-06 25.3 0.1 0.0006 19.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMG46408.1 - 0.00028 20.4 0.1 0.18 11.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EMG46408.1 - 0.00085 20.0 0.0 0.0021 18.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase2 PF03162.13 EMG46408.1 - 0.001 18.7 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EMG46408.1 - 0.021 14.4 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DLH PF01738.18 EMG46408.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Ctf8 PF09696.10 EMG46409.1 - 1e-33 116.6 0.1 4.1e-33 114.7 0.1 1.7 1 1 0 1 1 1 1 Ctf8 Rpr2 PF04032.16 EMG46410.1 - 3.3e-12 46.5 0.4 3.3e-12 46.5 0.4 2.1 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.6 EMG46410.1 - 0.48 10.4 2.6 13 5.8 0.2 2.4 2 0 0 2 2 2 0 Nudix N-terminal Zn_clus PF00172.18 EMG46411.1 - 2.6e-08 33.8 9.3 4.7e-08 33.0 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EMC1_C PF07774.13 EMG46412.1 - 1.4e-61 207.9 1.1 2.8e-61 206.9 1.1 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal Enterotoxin_b PF01376.18 EMG46412.1 - 0.12 12.6 0.7 5.4 7.3 0.0 3.3 3 0 0 3 3 3 0 Heat-labile enterotoxin beta chain RPAP1_C PF08620.10 EMG46413.1 - 1.8e-29 101.6 0.1 1.8e-29 101.6 0.1 2.4 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EMG46413.1 - 1.1e-18 66.7 10.3 3.2e-18 65.2 10.3 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal RRXRR PF14239.6 EMG46414.1 - 0.044 13.6 1.1 0.068 13.0 1.1 1.3 1 0 0 1 1 1 0 RRXRR protein Peptidase_S10 PF00450.22 EMG46415.1 - 3.2e-112 376.0 0.6 3.8e-112 375.8 0.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 EMG46415.1 - 0.0035 16.8 0.8 1.9 7.9 0.0 3.0 3 1 0 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EMG46415.1 - 0.027 13.8 0.1 10 5.3 0.0 2.7 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Rep_fac_C PF08542.11 EMG46416.1 - 1.2e-14 54.5 0.1 4.1e-14 52.7 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 EMG46416.1 - 4.6e-14 53.0 0.0 8.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EMG46416.1 - 2e-12 47.2 0.0 1.2e-10 41.4 0.0 2.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EMG46416.1 - 2.2e-08 34.3 0.1 5.1e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 AAA C-terminal domain Rad17 PF03215.15 EMG46416.1 - 7.6e-06 26.0 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 EMG46416.1 - 1e-05 25.3 0.0 2.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EMG46416.1 - 5.5e-05 23.0 0.0 0.00029 20.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EMG46416.1 - 0.00012 21.3 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 EMG46416.1 - 0.00014 21.7 0.0 0.0003 20.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EMG46416.1 - 0.00021 21.4 0.0 0.014 15.4 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EMG46416.1 - 0.00022 21.7 0.0 0.00034 21.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EMG46416.1 - 0.00042 19.8 0.0 0.0015 18.0 0.0 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EMG46416.1 - 0.00043 20.6 0.2 0.009 16.3 0.2 2.4 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EMG46416.1 - 0.00065 19.5 0.5 0.0012 18.7 0.5 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 EMG46416.1 - 0.0016 18.5 0.7 0.12 12.4 0.1 3.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EMG46416.1 - 0.0024 17.6 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EMG46416.1 - 0.0029 17.2 0.0 0.0059 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 EMG46416.1 - 0.019 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HMG-CoA_red PF00368.18 EMG46416.1 - 0.03 13.4 0.1 0.045 12.8 0.1 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase TIP49 PF06068.13 EMG46416.1 - 0.03 13.5 0.0 0.066 12.4 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 EMG46416.1 - 0.039 14.3 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMG46416.1 - 0.04 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMG46416.1 - 0.059 13.9 0.1 0.15 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain GPAT_N PF14829.6 EMG46416.1 - 0.071 13.1 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal RNA_helicase PF00910.22 EMG46416.1 - 0.072 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DDE_3 PF13358.6 EMG46416.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease AAA_25 PF13481.6 EMG46416.1 - 0.086 12.4 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Integrase_H2C2 PF17921.1 EMG46416.1 - 0.092 12.9 0.2 0.26 11.4 0.2 1.8 1 0 0 1 1 1 0 Integrase zinc binding domain IstB_IS21 PF01695.17 EMG46416.1 - 0.13 12.0 0.0 0.73 9.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Mid1 PF12929.7 EMG46417.1 - 1.5e-134 449.4 11.7 1.8e-134 449.1 11.7 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EMG46417.1 - 0.00051 20.6 5.0 0.045 14.4 5.0 2.8 1 1 0 1 1 1 1 Fz domain ThiF PF00899.21 EMG46418.1 - 1.9e-23 83.1 0.0 2e-21 76.5 0.0 2.5 3 0 0 3 3 3 2 ThiF family DEAD PF00270.29 EMG46419.1 - 8.5e-40 136.4 0.0 2.1e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG46419.1 - 5.9e-23 81.3 0.1 2.6e-22 79.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EMG46419.1 - 2.4e-17 62.9 0.3 4.2e-17 62.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 EMG46419.1 - 1.1e-05 24.8 4.9 0.006 15.8 0.0 2.2 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase UvrD-helicase PF00580.21 EMG46419.1 - 0.053 13.0 7.7 0.68 9.4 0.0 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 EMG46419.1 - 0.32 10.7 5.3 0.22 11.3 3.1 1.9 2 0 0 2 2 2 0 AAA domain NADH_u_ox_C PF12853.7 EMG46420.1 - 0.78 9.8 6.8 0.23 11.5 0.4 3.0 2 1 1 3 3 3 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF445 PF04286.12 EMG46420.1 - 3.7 7.2 12.6 0.83 9.4 9.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF445) PH_11 PF15413.6 EMG46421.1 - 3.3e-16 59.6 2.2 5.3e-16 58.9 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain MMM1 PF10296.9 EMG46421.1 - 4.9e-05 22.5 0.0 4.9e-05 22.5 0.0 3.6 3 1 1 4 4 4 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 EMG46421.1 - 0.02 15.4 0.4 0.02 15.4 0.4 3.5 2 1 1 3 3 3 0 PH domain DUF4752 PF15944.5 EMG46421.1 - 0.049 13.7 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) TMEM171 PF15471.6 EMG46421.1 - 0.085 11.8 0.0 0.23 10.4 0.0 1.5 1 1 0 1 1 1 0 Transmembrane protein family 171 FANCI_HD2 PF14680.6 EMG46421.1 - 0.14 11.4 2.2 0.31 10.2 2.2 1.5 1 0 0 1 1 1 0 FANCI helical domain 2 CTP_transf_1 PF01148.20 EMG46422.1 - 7.9e-79 265.2 16.6 1e-78 264.8 16.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family SUI1 PF01253.22 EMG46423.1 - 1.5e-28 99.1 0.4 2.4e-28 98.4 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Bromo_TP_like PF17027.5 EMG46423.1 - 0.038 14.1 0.2 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 Histone-fold protein CWC25 PF12542.8 EMG46424.1 - 1.3e-15 58.1 1.6 1.3e-15 58.1 1.6 2.3 2 1 0 2 2 2 1 Pre-mRNA splicing factor Cir_N PF10197.9 EMG46424.1 - 3.3e-11 43.2 12.3 3.3e-11 43.2 12.3 2.3 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3274 PF11678.8 EMG46424.1 - 0.056 12.7 2.3 0.093 12.0 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3274) CAML PF14963.6 EMG46424.1 - 3.9 7.5 10.7 0.56 10.3 5.7 1.8 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand CKS PF01111.19 EMG46425.1 - 7.8e-34 115.8 0.3 1e-33 115.4 0.3 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PI3_PI4_kinase PF00454.27 EMG46426.1 - 2.5e-52 178.2 0.1 8e-52 176.5 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 EMG46426.1 - 7.5e-20 70.7 1.0 3.4e-19 68.7 1.0 2.3 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 EMG46426.1 - 5.7e-14 51.6 0.1 1.8e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 EMG46426.1 - 3e-10 39.9 8.1 1.3e-09 37.8 8.1 2.1 1 1 0 1 1 1 1 FAT domain DUF3385 PF11865.8 EMG46426.1 - 0.0026 17.7 0.1 0.026 14.4 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) TPR_20 PF14561.6 EMG46426.1 - 0.0067 16.7 0.5 0.039 14.3 0.5 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Glyco_hydro_18 PF00704.28 EMG46427.1 - 1.6e-24 87.2 0.0 1.7e-23 83.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Flocculin_t3 PF13928.6 EMG46427.1 - 5.5e-11 42.8 19.9 5.5e-11 42.8 19.9 6.3 3 2 1 4 4 4 1 Flocculin type 3 repeat Clp1 PF06807.14 EMG46427.1 - 0.25 11.7 0.1 0.25 11.7 0.1 2.1 2 0 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 MIOX PF05153.15 EMG46428.1 - 7.9e-122 405.6 5.6 1e-121 405.2 5.6 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 EMG46428.1 - 0.031 14.5 0.3 0.97 9.7 0.3 2.6 1 1 0 1 1 1 0 HD domain Glyco_hydro_17 PF00332.18 EMG46429.1 - 0.013 15.1 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 TFIIA PF03153.13 EMG46429.1 - 0.16 12.0 35.2 0.3 11.0 35.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EMG46429.1 - 3.1 6.4 27.4 4.7 5.8 27.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mito_carr PF00153.27 EMG46430.1 - 3.5e-10 39.7 0.1 0.031 14.2 0.0 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein Arteri_Gl PF00951.18 EMG46430.1 - 0.045 13.6 0.2 0.079 12.8 0.2 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Dpy-30 PF05186.13 EMG46431.1 - 3.2e-13 49.1 0.0 4.9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Epiglycanin_TR PF05647.11 EMG46431.1 - 0.13 12.2 5.7 0.23 11.4 5.7 1.4 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like Syntaxin-6_N PF09177.11 EMG46432.1 - 1.9e-13 50.8 4.4 6.5e-13 49.1 0.2 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EMG46432.1 - 5.6e-07 29.5 1.4 5.6e-07 29.5 1.4 1.8 2 0 0 2 2 2 1 SNARE domain DUF4407 PF14362.6 EMG46432.1 - 0.0025 17.2 0.8 0.0031 16.9 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) BST2 PF16716.5 EMG46432.1 - 0.043 14.4 5.9 0.67 10.6 1.6 2.5 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 SLATT_5 PF18160.1 EMG46432.1 - 0.053 12.8 1.5 1.4 8.2 0.8 2.5 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF1640 PF07798.11 EMG46432.1 - 0.08 13.0 8.8 1.4 8.9 8.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Sec20 PF03908.13 EMG46432.1 - 0.48 10.4 5.9 0.22 11.5 0.6 2.3 2 0 0 2 2 2 0 Sec20 DUF16 PF01519.16 EMG46432.1 - 7.3 7.1 12.6 0.88 10.1 3.4 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF3219 PF11514.8 EMG46433.1 - 0.11 12.5 1.6 0.36 10.9 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3219) Pkinase PF00069.25 EMG46434.1 - 7.8e-73 245.1 0.0 1.7e-72 244.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG46434.1 - 5.7e-48 163.4 0.0 1e-47 162.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EMG46434.1 - 3.7e-21 75.2 0.5 1.5e-19 70.1 0.0 3.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 EMG46434.1 - 8.9e-06 25.2 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMG46434.1 - 2.6e-05 23.2 0.0 2.6e-05 23.2 0.0 3.1 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 EMG46434.1 - 0.042 13.8 2.0 0.28 11.1 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Arc_PepC PF06819.11 EMG46434.1 - 2.1 8.5 4.5 27 4.9 0.0 3.1 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain Say1_Mug180 PF10340.9 EMG46435.1 - 3.4e-29 101.8 0.1 4.9e-29 101.3 0.1 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EMG46435.1 - 6.9e-18 65.3 0.0 1.1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG46435.1 - 0.026 13.8 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S10 PF00450.22 EMG46435.1 - 0.03 13.7 0.0 3.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase DUF3012 PF11216.8 EMG46435.1 - 2.6 8.2 4.5 0.67 10.0 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) Bac_luciferase PF00296.20 EMG46436.1 - 3.8e-52 177.7 0.0 4.9e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase AhpC-TSA PF00578.21 EMG46436.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family PH PF00169.29 EMG46437.1 - 2.7e-19 69.6 9.2 4.1e-11 43.3 2.6 2.7 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 EMG46437.1 - 5.7e-07 29.9 14.1 0.0022 18.4 6.4 4.3 2 2 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 EMG46437.1 - 1.8e-06 28.1 2.4 3.7e-05 23.9 1.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 EMG46437.1 - 0.0014 18.9 0.7 0.28 11.5 0.4 2.4 2 0 0 2 2 2 1 Plant pleckstrin homology-like region Mcp5_PH PF12814.7 EMG46437.1 - 0.0021 18.2 1.7 0.32 11.1 0.0 2.9 2 1 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology BCL_N PF04714.13 EMG46437.1 - 0.023 14.7 1.0 0.065 13.3 1.0 1.7 1 0 0 1 1 1 0 BCL7, N-terminal conserver region NOA36 PF06524.12 EMG46437.1 - 0.5 9.6 4.4 0.85 8.9 4.4 1.4 1 0 0 1 1 1 0 NOA36 protein PH_9 PF15410.6 EMG46437.1 - 1.3 9.4 8.2 0.65 10.4 1.2 3.5 2 2 1 3 3 3 0 Pleckstrin homology domain CUE PF02845.16 EMG46438.1 - 6.4e-09 35.4 0.8 2.3e-07 30.4 0.1 3.0 2 0 0 2 2 2 1 CUE domain Smr PF01713.21 EMG46438.1 - 2e-07 31.3 0.0 4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Smr domain Lant_dehydr_C PF14028.6 EMG46438.1 - 0.14 11.7 0.2 0.25 10.8 0.2 1.4 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term APG12 PF04110.13 EMG46438.1 - 0.16 12.4 1.1 0.47 10.9 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 PIRT PF15099.6 EMG46438.1 - 0.36 10.4 2.0 22 4.6 1.3 2.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DnaJ_C PF01556.18 EMG46439.1 - 5.4e-33 114.2 0.4 8.4e-33 113.6 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMG46439.1 - 6.6e-22 77.4 7.7 1.2e-21 76.6 7.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EMG46439.1 - 2.9e-12 46.8 20.8 4.8e-12 46.1 20.8 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF5398 PF17376.2 EMG46439.1 - 0.03 14.9 1.4 0.03 14.9 1.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5398) Anti-TRAP PF15777.5 EMG46439.1 - 0.9 9.6 20.8 2.6 8.1 4.2 3.2 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_CBB3 PF13442.6 EMG46439.1 - 2.3 8.6 8.6 4 7.8 0.0 2.8 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III HypA PF01155.19 EMG46439.1 - 2.5 8.2 10.2 11 6.1 1.7 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EMG46439.1 - 4.8 6.8 8.4 7.1 6.2 0.8 2.3 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 zf-TFIIB PF13453.6 EMG46439.1 - 4.9 6.6 12.6 10 5.5 4.2 3.3 2 1 1 3 3 3 0 Transcription factor zinc-finger zinc-ribbons_6 PF07191.12 EMG46439.1 - 6.5 6.8 9.2 8.2 6.5 2.1 2.1 1 1 0 2 2 2 0 zinc-ribbons Cytochrome_C7 PF14522.6 EMG46439.1 - 9.1 6.4 14.9 5.4 7.1 2.7 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c polyprenyl_synt PF00348.17 EMG46440.1 - 1.3e-40 139.1 0.0 1.6e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase DUF4403 PF14356.6 EMG46441.1 - 0.002 16.9 0.5 0.0029 16.3 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4403) Cas_Cas6 PF01881.16 EMG46441.1 - 0.058 13.9 2.7 0.092 13.3 2.7 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas6 DRY_EERY PF09750.9 EMG46441.1 - 0.11 12.8 4.3 0.16 12.3 4.3 1.3 1 0 0 1 1 1 0 Alternative splicing regulator GDE_C PF06202.14 EMG46441.1 - 0.13 11.1 2.3 0.51 9.2 2.1 1.7 1 1 1 2 2 2 0 Amylo-alpha-1,6-glucosidase TCTP PF00838.17 EMG46441.1 - 1.5 9.1 4.9 2.9 8.2 4.9 1.4 1 0 0 1 1 1 0 Translationally controlled tumour protein TrmO_C PF18389.1 EMG46441.1 - 3.2 7.9 6.3 14 5.9 0.5 3.1 2 1 1 3 3 3 0 TrmO C-terminal domain TP_methylase PF00590.20 EMG46442.1 - 8.9e-18 65.0 0.0 1.3e-17 64.4 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DER1 PF04511.15 EMG46443.1 - 2.3e-14 53.8 7.5 2.3e-13 50.5 7.5 2.1 1 1 0 1 1 1 1 Der1-like family Hydrolase_6 PF13344.6 EMG46444.1 - 2.8e-22 78.7 0.0 5.5e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMG46444.1 - 3.1e-16 59.2 0.0 6.9e-15 54.9 0.0 2.9 2 1 0 2 2 2 1 HAD-hyrolase-like Bacteriocin_IIc PF10439.9 EMG46445.1 - 0.1 12.7 5.6 0.12 12.5 5.6 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Fcf1 PF04900.12 EMG46446.1 - 1.3e-33 115.3 2.1 2.2e-33 114.6 1.2 1.8 1 1 1 2 2 2 1 Fcf1 PIN_9 PF18477.1 EMG46446.1 - 5.5e-14 52.5 0.0 1.1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 EMG46446.1 - 0.0091 16.3 0.9 0.023 15.0 0.0 2.1 3 0 0 3 3 3 1 NTF2 fold immunity protein KCNQC3-Ank-G_bd PF11956.8 EMG46446.1 - 0.16 12.2 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 Peptidase_M18 PF02127.15 EMG46447.1 - 1.7e-104 350.0 0.0 2.2e-104 349.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) 2-Hacid_dh_C PF02826.19 EMG46448.1 - 4.4e-35 120.6 0.0 2.2e-34 118.3 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMG46448.1 - 2e-14 53.4 0.0 2.8e-14 52.9 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMG46448.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EMG46448.1 - 0.02 15.0 0.0 0.11 12.6 0.0 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Put_Phosphatase PF06888.12 EMG46449.1 - 0.0074 15.7 0.3 0.014 14.8 0.3 1.4 1 0 0 1 1 1 1 Putative Phosphatase Guanylate_kin PF00625.21 EMG46450.1 - 2.4e-68 229.4 0.0 2.7e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EMG46450.1 - 7.6e-07 29.7 0.2 3.1e-06 27.7 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMG46450.1 - 3e-05 24.6 0.1 6.7e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMG46450.1 - 3.9e-05 23.9 0.0 0.0001 22.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EMG46450.1 - 5.7e-05 23.2 0.2 0.00045 20.3 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EMG46450.1 - 6.4e-05 23.1 0.0 0.00027 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMG46450.1 - 0.00052 20.6 0.0 0.00065 20.2 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 EMG46450.1 - 0.00091 19.3 0.1 0.0021 18.1 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.6 EMG46450.1 - 0.00097 19.4 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EMG46450.1 - 0.00098 19.5 0.1 0.0057 17.0 0.0 2.1 2 1 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 EMG46450.1 - 0.0012 18.6 0.8 0.013 15.2 0.8 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMG46450.1 - 0.0014 18.4 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EMG46450.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EMG46450.1 - 0.0023 17.9 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_7 PF12775.7 EMG46450.1 - 0.0039 16.7 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 EMG46450.1 - 0.0063 16.9 0.5 0.02 15.3 0.5 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EMG46450.1 - 0.0076 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EMG46450.1 - 0.0084 16.0 0.3 0.014 15.3 0.3 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 EMG46450.1 - 0.016 14.9 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EMG46450.1 - 0.017 14.9 0.3 0.017 14.9 0.3 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EMG46450.1 - 0.019 14.1 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 EMG46450.1 - 0.021 14.1 0.0 0.031 13.5 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 EMG46450.1 - 0.024 13.9 0.1 0.12 11.6 0.0 1.7 1 1 0 2 2 2 0 KAP family P-loop domain NTPase_1 PF03266.15 EMG46450.1 - 0.024 14.5 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 NTPase cobW PF02492.19 EMG46450.1 - 0.076 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 EMG46450.1 - 0.08 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Cytidylate_kin PF02224.18 EMG46450.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_2 PF07724.14 EMG46450.1 - 0.083 13.0 0.1 1.4 9.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) MobB PF03205.14 EMG46450.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 EMG46450.1 - 0.092 12.7 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EMG46450.1 - 0.095 13.0 0.1 0.23 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EMG46450.1 - 0.11 12.9 0.3 0.42 11.0 0.1 1.9 1 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EMG46450.1 - 0.31 11.5 3.4 0.56 10.7 3.4 1.7 1 1 0 1 1 1 0 AAA domain HIG_1_N PF04588.13 EMG46451.1 - 1.4e-19 70.0 1.4 2.1e-19 69.5 1.4 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region SLBB PF10531.9 EMG46451.1 - 0.11 12.3 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 SLBB domain DUF4922 PF16269.5 EMG46452.1 - 0.01 15.6 0.2 0.019 14.7 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4922) ChAPs PF09295.10 EMG46453.1 - 7.1e-173 575.1 0.7 1.2e-172 574.3 0.7 1.4 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EMG46453.1 - 5.5e-05 23.6 0.0 0.0089 16.5 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG46453.1 - 0.0022 18.2 0.3 0.039 14.2 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EMG46453.1 - 0.0083 16.3 1.3 14 6.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMG46453.1 - 0.014 15.4 0.1 22 5.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 EMG46453.1 - 0.12 12.6 0.0 0.43 11.0 0.0 1.9 1 0 0 1 1 1 0 PPR repeat TPR_14 PF13428.6 EMG46453.1 - 0.15 13.0 0.0 9.1 7.4 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TFIID-31kDa PF02291.15 EMG46454.1 - 3.9e-47 159.3 0.1 6.2e-47 158.7 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit JUPITER PF17054.5 EMG46454.1 - 0.0097 15.4 3.5 0.012 15.1 3.5 1.1 1 0 0 1 1 1 1 Microtubule-Associated protein Jupiter DUF1929 PF09118.11 EMG46454.1 - 0.011 15.9 1.4 0.022 15.0 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1929) Macoilin PF09726.9 EMG46454.1 - 0.15 10.6 5.7 0.2 10.2 5.7 1.3 1 0 0 1 1 1 0 Macoilin family Histone PF00125.24 EMG46454.1 - 2.4 8.5 8.9 0.57 10.5 3.1 2.5 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TPK_catalytic PF04263.16 EMG46455.1 - 2.8e-35 121.0 0.0 5.1e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EMG46455.1 - 3.6e-09 36.2 0.0 6.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Ham1p_like PF01725.16 EMG46456.1 - 3e-56 190.3 0.0 3.3e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF3602 PF12223.8 EMG46457.1 - 4.2e-28 97.8 15.6 2.5e-11 44.0 0.0 4.1 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) DUF1190 PF06693.11 EMG46457.1 - 0.016 15.6 2.9 3.4 8.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1190) GTP1_OBG PF01018.22 EMG46457.1 - 0.06 12.9 7.4 1.6 8.3 0.0 3.7 3 1 0 4 4 4 0 GTP1/OBG DUF4834 PF16118.5 EMG46458.1 - 0.0044 18.0 0.9 0.0044 18.0 0.9 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4834) Ndc1_Nup PF09531.10 EMG46459.1 - 0.34 9.6 6.3 0.45 9.1 6.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 EMG46459.1 - 2.3 7.3 13.0 2.9 7.0 13.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 EMG46459.1 - 6 5.5 7.1 1.4 7.6 4.0 1.5 2 0 0 2 2 2 0 Presenilin SPX PF03105.19 EMG46459.1 - 7.9 6.3 20.9 12 5.7 20.9 1.2 1 0 0 1 1 1 0 SPX domain Hydrolase_6 PF13344.6 EMG46460.1 - 7e-27 93.5 0.0 1.8e-26 92.2 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMG46460.1 - 2.9e-06 27.7 0.0 0.11 12.8 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMG46460.1 - 4.5e-06 26.9 0.0 0.015 15.4 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMG46460.1 - 5.7e-06 26.3 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF885 PF05960.11 EMG46460.1 - 0.089 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Xpo1 PF08389.12 EMG46462.1 - 9.3e-29 100.4 4.5 9.3e-29 100.4 4.5 3.9 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 EMG46462.1 - 0.00016 21.5 0.3 0.0048 16.8 0.1 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEPN-like_int PF18867.1 EMG46463.1 - 0.046 13.6 0.2 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 HEPN-like integron domain MRP-L20 PF12824.7 EMG46464.1 - 3.5e-30 105.3 3.0 3.5e-30 105.3 3.0 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 LSM PF01423.22 EMG46464.1 - 8.1e-20 70.3 0.2 1.2e-19 69.7 0.2 1.3 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EMG46464.1 - 0.055 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Hfq PF17209.3 EMG46464.1 - 0.06 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Hfq protein UPRTase PF14681.6 EMG46465.1 - 7.5e-76 254.2 0.0 9.9e-76 253.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EMG46465.1 - 0.037 13.5 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 EMG46465.1 - 0.16 11.9 0.1 0.26 11.3 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.19 EMG46466.1 - 2.6e-129 431.4 0.0 1.3e-128 429.1 0.0 1.8 1 1 0 1 1 1 1 Actin EF-hand_6 PF13405.6 EMG46467.1 - 0.0069 16.2 0.0 0.039 13.9 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain RNA_pol_Rpb6 PF01192.22 EMG46468.1 - 1.4e-15 56.9 0.1 5.9e-15 54.9 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb6 Peptidase_M16 PF00675.20 EMG46469.1 - 6.9e-15 55.3 0.1 1e-14 54.7 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMG46469.1 - 3.7e-05 23.8 0.0 6.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Zn_clus PF00172.18 EMG46470.1 - 7.5e-07 29.2 11.3 1.5e-06 28.2 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMG46470.1 - 4.9e-05 22.5 0.6 0.00015 20.9 0.6 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Folliculin PF11704.8 EMG46471.1 - 1.9 8.4 9.9 10 5.9 4.0 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Zn_clus PF00172.18 EMG46472.1 - 7.4e-08 32.4 11.4 2e-07 31.0 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HemX PF04375.14 EMG46472.1 - 0.27 10.5 1.8 0.19 11.0 0.2 1.5 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Pox_A_type_inc PF04508.12 EMG46472.1 - 0.35 10.8 4.6 0.4 10.6 0.4 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Fungal_trans PF04082.18 EMG46473.1 - 1.2e-06 27.7 0.2 2.4e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Centro_C10orf90 PF17730.1 EMG46475.1 - 0.0021 16.9 0.6 0.0032 16.3 0.6 1.2 1 0 0 1 1 1 1 Centrosomal C10orf90 SLX9 PF15341.6 EMG46475.1 - 0.83 10.1 9.7 0.057 13.8 3.1 2.5 2 2 0 2 2 2 0 Ribosome biogenesis protein SLX9 Cyclin_N PF00134.23 EMG46476.1 - 9.9e-20 70.6 0.2 2.3e-19 69.4 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EMG46476.1 - 1.1e-10 42.1 0.1 1.1e-10 42.1 0.1 2.3 2 1 0 2 2 2 1 Cyclin Tctex-1 PF03645.13 EMG46476.1 - 0.042 14.1 0.5 0.23 11.7 0.0 2.3 2 1 0 2 2 2 0 Tctex-1 family FAM76 PF16046.5 EMG46476.1 - 0.68 9.2 5.3 1.1 8.6 5.3 1.2 1 0 0 1 1 1 0 FAM76 protein Vsr PF03852.15 EMG46478.1 - 0.076 12.9 0.5 0.95 9.4 0.1 2.3 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr Med14 PF08638.11 EMG46479.1 - 9.4e-58 194.8 0.6 9.4e-58 194.8 0.6 2.4 3 0 0 3 3 3 1 Mediator complex subunit MED14 SR-25 PF10500.9 EMG46479.1 - 0.013 15.1 0.2 0.026 14.2 0.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2726 PF10881.8 EMG46479.1 - 0.047 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Rtt106_N PF18215.1 EMG46479.1 - 0.081 12.7 0.8 1.4 8.7 0.2 2.7 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain PAC1 PF16094.5 EMG46479.1 - 0.75 8.9 3.7 1.8 7.7 3.7 1.5 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Pkinase PF00069.25 EMG46480.1 - 9.9e-39 133.3 0.0 1.9e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG46480.1 - 4.4e-22 78.6 0.0 2.6e-21 76.1 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG46480.1 - 0.12 11.7 0.1 0.68 9.2 0.1 2.0 1 1 0 1 1 1 0 Kinase-like WD40_like PF17005.5 EMG46481.1 - 1.7e-05 24.3 0.3 0.0062 15.9 0.1 3.2 2 1 2 4 4 4 2 WD40-like domain WD40 PF00400.32 EMG46481.1 - 0.00058 20.6 1.1 0.0091 16.8 0.1 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG46481.1 - 0.0011 19.2 0.0 23 5.4 0.0 4.8 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Phage_T4_Gp30_7 PF06919.11 EMG46481.1 - 0.016 15.4 0.0 0.074 13.2 0.0 2.1 2 0 0 2 2 2 0 Phage Gp30.7 protein SET PF00856.28 EMG46482.1 - 2.2e-16 60.7 0.9 4.1e-16 59.8 0.1 1.8 2 0 0 2 2 2 1 SET domain Mso1_Sec1_bdg PF14475.6 EMG46482.1 - 0.058 13.0 0.0 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 Sec1-binding region of Mso1 TRP PF06011.12 EMG46483.1 - 3.3e-80 269.9 9.8 8.3e-78 262.0 9.8 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EMG46483.1 - 0.026 14.9 2.1 0.15 12.4 1.2 2.4 2 0 0 2 2 2 0 ML-like domain GST_N PF02798.20 EMG46484.1 - 1.2e-10 41.6 0.0 6e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMG46484.1 - 1.1e-09 38.4 0.1 1.1e-09 38.4 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain EF1G PF00647.19 EMG46484.1 - 3.4e-07 30.3 0.8 7.4e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C_2 PF13410.6 EMG46484.1 - 2.8e-05 24.0 0.1 6.3e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMG46484.1 - 7.1e-05 23.1 0.6 0.00019 21.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMG46484.1 - 0.00027 21.1 0.2 0.00027 21.1 0.2 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF3402 PF11882.8 EMG46484.1 - 0.11 11.5 2.5 0.4 9.7 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) OAD_gamma PF04277.13 EMG46484.1 - 1.3 9.7 7.1 4.2 8.0 7.1 1.9 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Sec16_C PF12931.7 EMG46485.1 - 7e-63 213.1 0.0 1.5e-62 212.0 0.0 1.6 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EMG46485.1 - 5e-06 27.1 0.0 5e-06 27.1 0.0 3.5 4 0 0 4 4 4 1 Vesicle coat trafficking protein Sec16 mid-region Nup96 PF12110.8 EMG46485.1 - 0.059 12.5 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Nuclear protein 96 LRR_8 PF13855.6 EMG46486.1 - 0.0003 20.5 4.1 0.011 15.5 0.1 4.7 6 0 0 6 6 6 1 Leucine rich repeat LRR_4 PF12799.7 EMG46486.1 - 0.031 14.7 13.1 11 6.7 0.0 6.1 7 1 0 7 7 7 0 Leucine Rich repeats (2 copies) PRANC PF09372.10 EMG46486.1 - 0.066 13.5 1.7 3.7 8.0 0.2 3.7 3 1 0 3 3 3 0 PRANC domain FNIP PF05725.12 EMG46486.1 - 0.42 10.8 9.0 7.5 6.8 0.3 5.2 5 1 0 5 5 5 0 FNIP Repeat Zn_clus PF00172.18 EMG46487.1 - 0.00033 20.7 2.1 0.00033 20.7 2.1 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EMG46487.1 - 0.049 13.6 12.2 0.061 13.3 12.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 EMG46487.1 - 0.075 13.0 4.4 0.11 12.5 4.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CwfJ_C_1 PF04677.15 EMG46487.1 - 0.081 12.8 0.0 0.081 12.8 0.0 2.4 3 0 0 3 3 3 0 Protein similar to CwfJ C-terminus 1 MFS_1 PF07690.16 EMG46488.1 - 6.3e-30 104.3 29.4 8.8e-30 103.8 29.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_S7 PF00177.21 EMG46489.1 - 1.1e-35 122.5 3.4 1.1e-35 122.5 3.4 1.4 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Lyase_1 PF00206.20 EMG46489.1 - 0.037 13.4 0.1 0.072 12.5 0.0 1.4 1 1 0 1 1 1 0 Lyase MFS_1 PF07690.16 EMG46490.1 - 1.7e-18 66.7 42.5 1.7e-18 66.7 42.5 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG46490.1 - 0.0001 21.4 15.0 0.0001 21.4 15.0 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Gag_p12 PF01141.18 EMG46490.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 MFS_1 PF07690.16 EMG46491.1 - 4e-24 85.2 64.6 1.4e-18 67.0 38.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMG46491.1 - 0.002 17.1 0.2 0.002 17.1 0.2 2.6 1 1 0 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 EMG46492.1 - 2e-20 73.0 45.3 2e-20 73.0 45.3 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EMG46492.1 - 0.00051 19.0 26.3 0.0066 15.4 0.6 2.7 1 1 0 2 2 2 2 MFS_1 like family AAA PF00004.29 EMG46493.1 - 5.5e-43 146.5 0.0 9.3e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EMG46493.1 - 2e-28 98.1 0.0 6.7e-28 96.5 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EMG46493.1 - 3.7e-23 81.4 3.3 9e-23 80.1 3.3 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EMG46493.1 - 2.7e-06 27.1 0.0 1e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 EMG46493.1 - 5.4e-06 26.8 1.0 0.011 16.1 0.0 4.1 5 0 0 5 5 4 1 RNA helicase AAA_5 PF07728.14 EMG46493.1 - 6.4e-06 26.2 0.1 3.9e-05 23.7 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMG46493.1 - 8.5e-06 26.2 0.1 0.00016 22.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EMG46493.1 - 2.9e-05 23.9 0.0 4.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EMG46493.1 - 4.2e-05 23.3 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 EMG46493.1 - 4.2e-05 22.8 0.0 0.00021 20.5 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EMG46493.1 - 0.00011 22.5 0.1 0.0035 17.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMG46493.1 - 0.00037 20.5 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EMG46493.1 - 0.00049 19.4 0.0 0.00091 18.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EMG46493.1 - 0.00062 20.3 0.1 0.0029 18.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EMG46493.1 - 0.0013 18.8 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EMG46493.1 - 0.002 18.3 0.1 0.0072 16.5 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 EMG46493.1 - 0.0028 17.4 0.0 0.0095 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EMG46493.1 - 0.015 15.8 0.0 0.049 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMG46493.1 - 0.018 14.6 0.1 0.45 10.1 0.1 2.4 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EMG46493.1 - 0.03 13.7 0.0 0.082 12.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EMG46493.1 - 0.034 13.6 0.0 0.1 12.1 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EMG46493.1 - 0.055 12.9 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.11 EMG46493.1 - 0.065 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Torsin Zeta_toxin PF06414.12 EMG46493.1 - 0.076 12.3 0.1 1.3 8.2 0.1 2.4 1 1 1 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 EMG46493.1 - 0.098 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EMG46493.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 EMG46493.1 - 0.1 12.5 0.0 0.62 10.0 0.0 2.0 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 EMG46493.1 - 0.11 11.8 0.3 6.5 6.0 0.0 2.5 2 1 1 3 3 3 0 KaiC CPT PF07931.12 EMG46493.1 - 0.15 11.9 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 EMG46493.1 - 0.16 11.7 0.3 0.51 10.0 0.0 2.0 3 0 0 3 3 3 0 Cytidylate kinase NCBP3 PF10309.9 EMG46494.1 - 1.2e-25 89.1 0.2 2.3e-25 88.2 0.2 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 LSM PF01423.22 EMG46495.1 - 2.3e-19 68.8 0.5 4e-19 68.1 0.5 1.4 1 0 0 1 1 1 1 LSM domain DUF2688 PF10892.8 EMG46501.1 - 0.0083 15.6 6.9 1.2 8.7 0.1 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF2688) PA26 PF04636.13 EMG46501.1 - 5.2 5.9 14.7 8.2 5.2 14.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF5401 PF17380.2 EMG46501.1 - 6.6 4.7 25.8 9.2 4.2 25.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Proteasome PF00227.26 EMG46502.1 - 9e-24 84.0 0.0 1.2e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Yqai PF09466.10 EMG46502.1 - 0.68 10.3 2.5 0.43 10.9 0.4 1.8 2 0 0 2 2 2 0 Hypothetical protein Yqai DPPIV_N PF00930.21 EMG46503.1 - 1.2e-91 307.1 5.7 1.7e-91 306.6 5.7 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EMG46503.1 - 4.9e-44 150.3 0.1 9.2e-44 149.5 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EMG46503.1 - 0.00087 18.9 0.0 0.0024 17.4 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EMG46503.1 - 0.00097 19.8 0.0 0.0027 18.3 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.12 EMG46503.1 - 0.0022 17.9 2.0 2.9 7.9 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat AXE1 PF05448.12 EMG46503.1 - 0.016 13.9 0.0 0.044 12.5 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EMG46503.1 - 0.023 14.5 0.0 0.077 12.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EMG46503.1 - 0.054 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EMG46503.1 - 0.08 12.5 0.1 0.21 11.1 0.0 1.7 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) NDUFA12 PF05071.16 EMG46504.1 - 1.1e-09 38.9 0.9 2.4e-09 37.9 0.9 1.7 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Sterile PF03015.19 EMG46504.1 - 0.063 13.5 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 Male sterility protein WD40 PF00400.32 EMG46505.1 - 1.8e-07 31.7 4.9 0.48 11.4 0.1 7.0 8 0 0 8 8 8 2 WD domain, G-beta repeat BBS2_N PF14781.6 EMG46505.1 - 0.18 11.7 1.6 3 7.8 0.1 3.4 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal Arabino_trans_N PF17689.1 EMG46505.1 - 1.7 8.8 4.9 3.1 8.0 0.1 2.4 2 0 0 2 2 2 0 Arabinosyltransferase concanavalin like domain SART-1 PF03343.13 EMG46506.1 - 9.4e-51 173.1 66.8 1e-42 146.6 61.7 3.6 2 1 0 2 2 2 2 SART-1 family E1-E2_ATPase PF00122.20 EMG46507.1 - 1.9e-45 154.6 2.1 1.9e-45 154.6 2.1 2.4 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EMG46507.1 - 4.4e-31 108.8 0.0 7.1e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EMG46507.1 - 5.3e-14 52.4 1.4 1.9e-13 50.7 1.4 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EMG46507.1 - 1.1e-07 31.8 6.7 1.6e-06 28.0 0.7 3.6 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase Grg1 PF11034.8 EMG46508.1 - 0.31 11.3 0.1 0.31 11.3 0.1 2.8 3 0 0 3 3 3 0 Glucose-repressible protein Grg1 DNA_pol_phi PF04931.13 EMG46508.1 - 2.4 6.1 7.8 3.3 5.7 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Gti1_Pac2 PF09729.9 EMG46509.1 - 2.2e-33 115.9 11.3 6.6e-29 101.3 0.1 3.4 2 1 1 3 3 3 3 Gti1/Pac2 family DUF4138 PF13595.6 EMG46509.1 - 0.008 15.5 1.3 0.014 14.7 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4138) Atx10homo_assoc PF09759.9 EMG46510.1 - 2.6e-35 120.4 1.8 3.3e-35 120.0 0.5 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 EMG46510.1 - 0.72 9.9 5.0 12 5.9 0.1 3.4 2 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Thr_synth_N PF14821.6 EMG46511.1 - 5.6e-30 103.4 0.0 2.5e-29 101.3 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EMG46511.1 - 3.9e-14 52.7 0.0 6.3e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tam41_Mmp37 PF09139.11 EMG46512.1 - 1.1e-101 340.6 1.6 1.3e-101 340.3 1.6 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DUF1882 PF08966.11 EMG46512.1 - 0.0089 16.3 0.4 0.05 13.8 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1882) Pox_TAA1 PF03295.14 EMG46512.1 - 0.11 12.4 0.5 0.3 11.0 0.1 1.9 2 0 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal Fungal_trans PF04082.18 EMG46513.1 - 1.6e-11 43.8 0.4 4.3e-11 42.3 0.4 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG46513.1 - 5.1e-10 39.3 12.7 1.2e-09 38.2 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Say1_Mug180 PF10340.9 EMG46514.1 - 4.7e-31 108.0 0.1 7.1e-31 107.4 0.1 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EMG46514.1 - 1.5e-14 54.3 0.0 2.2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Per1 PF04080.13 EMG46515.1 - 5.3e-92 308.2 18.8 5.3e-92 308.2 18.8 2.0 2 0 0 2 2 2 1 Per1-like family NUC202 PF08166.12 EMG46515.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 NUC202 domain Adap_comp_sub PF00928.21 EMG46517.1 - 1.3e-11 44.3 0.6 2.2e-11 43.7 0.6 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMG46517.1 - 6.2e-09 35.9 0.3 1.2e-08 35.0 0.3 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PDEase_II PF02112.15 EMG46518.1 - 2.4e-113 378.7 6.3 3e-113 378.4 6.3 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EMG46518.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain SAP30_Sin3_bdg PF13867.6 EMG46519.1 - 2.9e-08 33.9 0.7 2.1e-07 31.1 0.0 2.4 3 0 0 3 3 3 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Tombus_movement PF05318.12 EMG46519.1 - 2.3 9.1 5.9 12 6.8 1.0 2.2 2 0 0 2 2 2 0 Tombusvirus movement protein SAP130_C PF16014.5 EMG46520.1 - 3 6.9 6.0 3.5 6.6 6.0 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DUF4336 PF14234.6 EMG46521.1 - 0.012 14.8 0.1 0.041 13.1 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4336) DUF4336 PF14234.6 EMG46522.1 - 0.0092 15.2 0.0 0.47 9.6 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4336) PhyH PF05721.13 EMG46523.1 - 4e-14 53.4 0.0 9.2e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AraC_binding PF02311.19 EMG46523.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Aldolase_II PF00596.21 EMG46524.1 - 8.7e-51 172.5 0.8 1.1e-50 172.2 0.8 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HIRA_B PF09453.10 EMG46525.1 - 0.043 13.7 0.7 0.096 12.6 0.7 1.6 1 0 0 1 1 1 0 HIRA B motif WD40 PF00400.32 EMG46525.1 - 0.087 13.7 0.3 0.18 12.7 0.3 1.5 1 0 0 1 1 1 0 WD domain, G-beta repeat CUE PF02845.16 EMG46526.1 - 4e-12 45.6 0.0 6.7e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 EMG46526.1 - 0.00044 20.2 0.2 0.00077 19.4 0.2 1.4 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 DUF4692 PF15763.5 EMG46526.1 - 0.045 14.2 4.3 0.086 13.3 4.3 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Ctr PF04145.15 EMG46526.1 - 0.047 14.3 0.2 0.091 13.4 0.2 1.4 1 0 0 1 1 1 0 Ctr copper transporter family Kei1 PF08552.11 EMG46526.1 - 0.093 12.6 0.4 0.13 12.1 0.4 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Macoilin PF09726.9 EMG46526.1 - 0.11 11.0 2.3 0.11 11.0 2.3 1.2 1 0 0 1 1 1 0 Macoilin family DUF1635 PF07795.11 EMG46526.1 - 0.39 10.6 5.3 0.69 9.7 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) RSRP PF17069.5 EMG46526.1 - 4.9 6.7 20.7 7.7 6.0 20.7 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 DUF515 PF04415.12 EMG46526.1 - 5.8 5.2 9.0 7.7 4.8 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MARVEL PF01284.23 EMG46527.1 - 5.8e-16 58.8 14.3 7.7e-16 58.4 14.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3328 PF11807.8 EMG46527.1 - 0.23 11.2 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) MNSV_P7B PF06692.11 EMG46527.1 - 6.1 6.9 5.8 0.55 10.3 0.9 1.8 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein Thioredoxin PF00085.20 EMG46528.1 - 9.4e-24 83.4 0.3 2e-23 82.4 0.3 1.6 1 1 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EMG46528.1 - 5.2e-11 42.4 0.2 7.7e-11 41.9 0.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EMG46528.1 - 8.4e-08 32.6 0.8 1.7e-07 31.6 0.3 1.8 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMG46528.1 - 1.3e-06 28.6 0.3 0.00084 19.6 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like TraF PF13728.6 EMG46528.1 - 5.4e-05 23.1 0.0 8.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 EMG46528.1 - 0.0018 18.2 0.1 0.018 15.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain ERp29_N PF07912.13 EMG46528.1 - 0.0023 18.1 0.4 0.0048 17.1 0.4 1.5 1 1 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_7 PF13899.6 EMG46528.1 - 0.019 15.1 0.2 0.059 13.5 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 EMG46528.1 - 0.027 14.4 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 AhpC/TSA family FSH1 PF03959.13 EMG46529.1 - 1.2e-67 227.6 0.1 1.7e-67 227.2 0.1 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EMG46529.1 - 0.0014 18.5 0.5 0.047 13.5 0.5 2.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF1836 PF08876.11 EMG46529.1 - 0.049 13.7 0.3 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) Pup PF05639.11 EMG46529.1 - 0.12 13.3 2.0 0.39 11.6 2.0 1.8 1 0 0 1 1 1 0 Pup-like protein DLH PF01738.18 EMG46530.1 - 2.5e-25 89.3 0.0 2.9e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EMG46530.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family SIR4_SID PF16991.5 EMG46531.1 - 0.023 14.8 2.8 0.87 9.6 0.2 2.2 1 1 0 2 2 2 0 Sir4 SID domain CAT PF00302.18 EMG46531.1 - 0.041 13.8 3.1 4.6 7.1 0.2 2.7 1 1 1 2 2 2 0 Chloramphenicol acetyltransferase Tup_N PF08581.10 EMG46531.1 - 0.044 14.1 1.5 0.044 14.1 1.5 2.5 3 0 0 3 3 3 0 Tup N-terminal Med29 PF11568.8 EMG46531.1 - 0.14 12.4 2.4 0.18 12.0 2.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 29 DUF1664 PF07889.12 EMG46531.1 - 0.15 12.1 1.1 1.4 9.0 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Inhibitor_I29 PF08246.12 EMG46531.1 - 1.3 9.6 6.0 0.18 12.3 1.0 2.1 2 1 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) HHH PF00633.23 EMG46532.1 - 0.0067 16.2 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif DDE_Tnp_ISL3 PF01610.17 EMG46532.1 - 0.092 12.5 0.2 0.18 11.5 0.2 1.5 1 1 0 1 1 1 0 Transposase Kdo PF06293.14 EMG46534.1 - 6.5e-07 28.9 0.0 4.3e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMG46534.1 - 8.8e-06 25.8 0.0 0.00026 21.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EMG46534.1 - 1.3e-05 24.7 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EMG46534.1 - 0.00014 21.5 0.0 0.00035 20.2 0.0 1.7 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 EMG46534.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1679 PF07914.11 EMG46534.1 - 0.0026 16.7 0.0 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EMG46534.1 - 0.044 13.1 0.0 0.074 12.4 0.0 1.4 2 0 0 2 2 2 0 Ecdysteroid kinase SPRY PF00622.28 EMG46535.1 - 0.0025 17.9 0.5 0.0085 16.2 0.0 2.1 2 0 0 2 2 2 1 SPRY domain LisH PF08513.11 EMG46535.1 - 0.0033 17.3 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 LisH LisH_2 PF16045.5 EMG46535.1 - 0.054 12.5 0.0 0.15 11.1 0.0 1.8 1 0 0 1 1 1 0 LisH Abhydrolase_2 PF02230.16 EMG46536.1 - 2.2e-57 194.4 0.0 2.6e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EMG46536.1 - 1.6e-08 34.5 0.0 5.5e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EMG46536.1 - 9.8e-07 28.3 0.0 0.0081 15.5 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 EMG46536.1 - 9.2e-06 25.4 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EMG46536.1 - 0.00034 21.3 0.0 0.0004 21.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EMG46536.1 - 0.0022 17.9 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EMG46536.1 - 0.0095 15.6 0.6 0.14 11.8 0.0 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EMG46536.1 - 0.032 14.1 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 EMG46536.1 - 0.035 14.1 0.0 0.089 12.8 0.0 1.6 1 1 1 2 2 2 0 Cutinase Peptidase_M20 PF01546.28 EMG46537.1 - 2.5e-33 115.5 0.0 3.9e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMG46537.1 - 4.5e-10 39.4 0.0 9.1e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMG46537.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 60KD_IMP PF02096.20 EMG46538.1 - 5e-12 46.0 1.0 7e-12 45.6 1.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Spt4 PF06093.13 EMG46539.1 - 1e-30 105.6 0.1 1.2e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger A2L_zn_ribbon PF08792.10 EMG46539.1 - 0.035 13.8 0.9 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain WG_beta_rep PF14903.6 EMG46539.1 - 0.038 14.3 0.1 0.11 12.8 0.1 1.9 1 1 0 1 1 1 0 WG containing repeat TackOD1 PF18551.1 EMG46539.1 - 0.069 12.8 1.1 0.097 12.3 1.1 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 AAA PF00004.29 EMG46540.1 - 2.5e-49 167.1 0.0 1.5e-42 145.2 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMG46540.1 - 2.9e-10 39.8 0.0 7.6e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EMG46540.1 - 4.3e-06 26.9 0.0 2.8e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EMG46540.1 - 7.5e-06 25.8 0.0 7.3e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 EMG46540.1 - 9.3e-06 26.1 0.6 8.2e-05 23.0 0.1 2.9 2 2 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 EMG46540.1 - 9.1e-05 22.6 0.0 0.4 10.8 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 EMG46540.1 - 0.0012 18.8 0.0 0.0055 16.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.25 EMG46540.1 - 0.0015 18.5 0.1 0.0015 18.5 0.1 2.4 3 0 0 3 3 1 1 Bromodomain AAA_22 PF13401.6 EMG46540.1 - 0.0016 18.7 1.2 0.1 12.8 0.2 3.7 2 2 1 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EMG46540.1 - 0.0035 17.1 0.0 1.2 8.8 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain ResIII PF04851.15 EMG46540.1 - 0.004 17.2 1.2 0.047 13.7 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EMG46540.1 - 0.0073 16.3 0.1 0.058 13.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EMG46540.1 - 0.015 15.7 0.0 0.12 12.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 EMG46540.1 - 0.023 15.2 0.1 0.24 11.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMG46540.1 - 0.027 14.6 0.0 0.076 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Shugoshin_C PF07557.11 EMG46540.1 - 0.047 13.5 1.8 0.2 11.5 0.5 2.6 2 0 0 2 2 2 0 Shugoshin C terminus Mg_chelatase PF01078.21 EMG46540.1 - 0.051 13.0 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EMG46540.1 - 0.072 12.6 0.0 0.36 10.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 EMG46540.1 - 0.074 12.8 0.0 0.29 10.9 0.0 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EMG46540.1 - 0.11 12.4 0.0 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EMG46540.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMG46540.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMG46540.1 - 0.12 12.9 0.0 0.12 12.9 0.0 3.0 2 1 0 2 2 1 0 ABC transporter DUF2508 PF10704.9 EMG46540.1 - 1.5 9.1 9.2 1.1 9.4 4.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Sigma70_ner PF04546.13 EMG46541.1 - 0.052 13.4 2.7 0.27 11.1 0.3 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF3958 PF13125.6 EMG46541.1 - 0.26 11.5 5.4 0.079 13.2 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) ACCA PF03255.14 EMG46541.1 - 0.69 9.8 3.5 11 5.9 0.5 2.5 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TOM20_plant PF06552.12 EMG46542.1 - 0.11 12.2 0.8 9 6.0 0.1 2.3 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 tRNA-synt_1g PF09334.11 EMG46543.1 - 7.1e-96 321.3 0.4 6.4e-95 318.2 0.4 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EMG46543.1 - 1.9e-22 79.3 2.5 5.9e-11 41.3 0.0 3.1 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EMG46543.1 - 1.4e-12 47.6 0.0 7.7e-07 28.7 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Yip1 PF04893.17 EMG46543.1 - 3.7e-10 39.8 9.3 5.7e-10 39.2 9.3 1.3 1 0 0 1 1 1 1 Yip1 domain Anticodon_1 PF08264.13 EMG46543.1 - 0.0035 17.3 0.2 0.0081 16.1 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF3828 PF12883.7 EMG46543.1 - 0.043 14.2 0.4 1.1 9.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3828) SRP54 PF00448.22 EMG46544.1 - 2.7e-48 164.2 3.7 6.5e-48 163.0 2.4 2.2 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain MeaB PF03308.16 EMG46544.1 - 3.2e-05 23.1 0.0 8.5e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP-alpha_N PF04086.13 EMG46544.1 - 9.5e-05 22.5 5.8 0.0002 21.4 5.8 1.6 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal AAA_22 PF13401.6 EMG46544.1 - 0.00014 22.2 0.1 0.001 19.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain SRP54_N PF02881.19 EMG46544.1 - 0.00019 21.6 0.7 0.00062 19.9 0.0 2.3 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 EMG46544.1 - 0.00075 18.8 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.6 EMG46544.1 - 0.001 18.9 0.0 0.0031 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMG46544.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EMG46544.1 - 0.0027 17.8 0.0 0.014 15.5 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMG46544.1 - 0.0027 17.6 1.4 0.042 13.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain RNA_binding PF01877.17 EMG46544.1 - 0.011 16.0 0.5 0.011 16.0 0.5 1.9 2 0 0 2 2 2 0 RNA binding AAA_17 PF13207.6 EMG46544.1 - 0.012 16.0 0.1 0.012 16.0 0.1 2.8 3 1 0 3 3 2 0 AAA domain ArsA_ATPase PF02374.15 EMG46544.1 - 0.014 14.6 2.0 0.97 8.5 0.0 3.0 2 2 1 3 3 3 0 Anion-transporting ATPase AAA_25 PF13481.6 EMG46544.1 - 0.031 13.9 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 EMG46544.1 - 0.052 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Helicase Rsc14 PF08586.10 EMG46544.1 - 0.068 14.0 0.2 0.068 14.0 0.2 2.7 3 0 0 3 3 2 0 RSC complex, Rsc14/Ldb7 subunit AAA_16 PF13191.6 EMG46544.1 - 0.079 13.3 0.0 0.26 11.7 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 EMG46544.1 - 0.083 12.9 0.5 0.53 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain PS_Dcarbxylase PF02666.15 EMG46545.1 - 1.9e-56 190.8 0.1 2.9e-56 190.2 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EMG46545.1 - 1.6e-25 89.3 1.1 1.6e-13 50.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain zf-C2H2_4 PF13894.6 EMG46546.1 - 3.9e-08 33.5 18.3 0.0002 21.9 0.4 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EMG46546.1 - 6.7e-08 32.6 24.0 3.3e-06 27.2 0.8 3.8 4 0 0 4 4 3 3 Zinc finger, C2H2 type CpXC PF14353.6 EMG46546.1 - 0.00013 22.0 0.6 0.011 15.7 0.1 2.4 2 0 0 2 2 2 1 CpXC protein zf-C2H2_8 PF15909.5 EMG46546.1 - 0.00049 20.4 5.1 0.4 11.0 0.6 3.1 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 EMG46546.1 - 0.00049 20.4 0.6 0.00049 20.4 0.6 5.0 5 1 0 5 5 4 1 Zinc-finger double domain zf-BED PF02892.15 EMG46546.1 - 0.0031 17.5 2.6 0.0031 17.5 2.6 3.3 2 1 1 3 3 3 1 BED zinc finger zf-C2H2_3rep PF18868.1 EMG46546.1 - 0.0046 17.6 3.9 2.2 9.0 0.6 3.1 1 1 2 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf_Hakai PF18408.1 EMG46546.1 - 0.022 14.5 2.8 0.7 9.7 0.6 2.5 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-C2H2_6 PF13912.6 EMG46546.1 - 0.024 14.6 11.7 0.026 14.5 0.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 EMG46546.1 - 0.026 14.1 3.7 1.1 8.9 0.2 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 EMG46546.1 - 0.028 14.9 4.0 0.81 10.2 0.0 3.4 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 EMG46546.1 - 0.03 14.6 8.9 5.4 7.4 0.3 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 EMG46546.1 - 0.052 13.6 0.6 0.12 12.4 0.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EMG46546.1 - 0.055 13.6 4.0 1.4 9.1 0.2 3.3 3 0 0 3 3 3 0 Zinc ribbon domain zf-HIT PF04438.16 EMG46546.1 - 0.11 12.4 2.4 10 6.1 0.2 2.3 2 0 0 2 2 2 0 HIT zinc finger zinc_ribbon_15 PF17032.5 EMG46546.1 - 0.12 13.1 3.6 0.097 13.4 1.3 1.9 2 0 0 2 2 2 0 zinc-ribbon family zf-C2H2_11 PF16622.5 EMG46546.1 - 0.18 11.6 8.3 0.39 10.5 0.1 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF629 PF04780.12 EMG46546.1 - 0.28 9.7 5.1 0.59 8.6 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zinc_ribbon_4 PF13717.6 EMG46546.1 - 0.52 10.3 6.8 3.3 7.7 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain FOXP-CC PF16159.5 EMG46546.1 - 0.64 10.7 2.9 4 8.1 0.7 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-ribbon_3 PF13248.6 EMG46546.1 - 0.81 9.2 3.7 12 5.4 0.3 2.9 3 0 0 3 3 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.8 EMG46546.1 - 2.9 8.3 14.7 2.1 8.8 0.6 3.4 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3 PF13878.6 EMG46546.1 - 4.4 7.2 6.6 1.1 9.2 0.7 2.6 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn_ribbon_recom PF13408.6 EMG46546.1 - 4.9 7.8 7.6 1 9.9 2.8 2.3 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-met PF12874.7 EMG46546.1 - 8 7.0 8.2 1.5 9.3 0.1 3.2 4 0 0 4 4 3 0 Zinc-finger of C2H2 type Ribonuclease_T2 PF00445.18 EMG46547.1 - 3.1e-40 138.4 3.1 3.1e-40 138.4 3.1 1.6 2 0 0 2 2 2 1 Ribonuclease T2 family Fungal_trans_2 PF11951.8 EMG46548.1 - 2.3e-14 53.0 3.7 3.1e-14 52.6 3.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG46548.1 - 3.1e-08 33.6 13.0 7.2e-08 32.4 13.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IF4E PF01652.18 EMG46550.1 - 1.4e-26 93.2 0.3 2.3e-26 92.5 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Sugar_tr PF00083.24 EMG46551.1 - 5.7e-66 223.2 13.4 6.4e-66 223.1 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG46551.1 - 0.00018 20.5 9.7 0.00018 20.5 9.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.12 EMG46551.1 - 0.023 14.2 1.8 0.056 12.9 1.8 1.6 1 0 0 1 1 1 0 Emopamil binding protein 7TM_GPCR_Srv PF10323.9 EMG46551.1 - 0.044 13.1 5.0 0.59 9.4 1.6 2.5 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF4149 PF13664.6 EMG46551.1 - 0.18 12.1 3.2 0.42 11.0 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) UDPGP PF01704.18 EMG46552.1 - 5.9e-44 150.3 0.1 8.1e-44 149.9 0.1 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Septin PF00735.18 EMG46553.1 - 2.1e-59 201.1 3.1 2.5e-59 200.9 3.1 1.1 1 0 0 1 1 1 1 Septin SLS PF14611.6 EMG46554.1 - 9.8e-24 84.4 3.6 2.4e-23 83.1 3.6 1.7 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator TLV_coat PF00429.19 EMG46555.1 - 0.013 14.3 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Mannosyl_trans3 PF11051.8 EMG46556.1 - 2e-81 273.4 0.9 4.2e-81 272.3 0.9 1.6 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 EMG46556.1 - 0.021 14.4 0.3 0.049 13.2 0.3 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 8 OKR_DC_1_N PF03709.15 EMG46556.1 - 0.15 12.4 0.1 2.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Ribonuclease_T2 PF00445.18 EMG46557.1 - 1.7e-39 136.0 1.8 1.7e-39 136.0 1.8 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family AdoHcyase PF05221.17 EMG46558.1 - 8.6e-130 432.2 0.0 1.6e-74 250.8 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EMG46558.1 - 5.2e-82 273.7 2.8 8.3e-82 273.0 2.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMG46558.1 - 2.8e-08 33.3 0.1 1.1e-07 31.4 0.1 1.9 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EMG46558.1 - 0.054 13.2 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 EMG46558.1 - 0.066 13.5 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain GATA PF00320.27 EMG46559.1 - 6.1e-15 54.5 3.4 1.3e-14 53.5 3.4 1.6 1 0 0 1 1 1 1 GATA zinc finger Cep57_CLD PF14073.6 EMG46559.1 - 0.14 12.2 1.7 0.36 10.8 1.7 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 TF_Zn_Ribbon PF08271.12 EMG46559.1 - 0.15 11.6 0.4 0.34 10.4 0.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Sec63 PF02889.16 EMG46561.1 - 9.4e-125 414.9 0.9 1.6e-79 266.7 0.2 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EMG46561.1 - 1.1e-50 171.8 0.8 3.1e-25 89.0 0.7 3.6 5 0 0 5 5 4 2 DEAD/DEAH box helicase ResIII PF04851.15 EMG46561.1 - 3.4e-28 98.8 0.3 1.1e-14 54.8 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMG46561.1 - 7.5e-18 64.9 0.0 1.8e-07 31.5 0.0 4.0 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EMG46561.1 - 1.7e-07 31.6 0.2 0.036 14.3 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EMG46561.1 - 1.6e-05 25.2 0.3 0.18 12.1 0.4 2.8 2 0 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 EMG46561.1 - 0.0003 20.9 0.1 0.0011 19.2 0.1 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA PF00004.29 EMG46561.1 - 0.00065 20.1 4.8 0.28 11.6 0.0 4.0 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EMG46561.1 - 0.002 17.6 0.0 0.18 11.3 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 EMG46561.1 - 0.0051 15.9 0.0 3.4 6.6 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein SWI2_SNF2 PF18766.1 EMG46561.1 - 0.028 14.1 0.2 0.89 9.2 0.0 2.8 3 0 0 3 3 3 0 SWI2/SNF2 ATPase IstB_IS21 PF01695.17 EMG46561.1 - 0.088 12.5 0.2 6.9 6.4 0.0 3.6 4 0 0 4 4 3 0 IstB-like ATP binding protein Microtub_bd PF16796.5 EMG46561.1 - 0.12 12.3 0.1 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Microtubule binding TniB PF05621.11 EMG46561.1 - 0.44 9.9 2.2 21 4.4 0.1 3.5 4 0 0 4 4 4 0 Bacterial TniB protein PTS_IIB PF02302.17 EMG46561.1 - 1.2 9.9 2.9 80 4.0 0.1 3.6 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit Alpha-amylase PF00128.24 EMG46562.1 - 2.6e-122 408.6 1.1 2.6e-122 408.6 1.1 1.7 1 1 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EMG46562.1 - 1.7e-05 24.1 0.1 7.7e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Sugar_tr PF00083.24 EMG46563.1 - 3.7e-81 273.3 28.9 4.7e-81 273.0 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG46563.1 - 1.3e-14 53.9 23.0 1.3e-14 53.9 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Efg1 PF10153.9 EMG46564.1 - 2.8e-34 117.9 13.3 2.8e-34 117.9 13.3 1.9 2 1 0 2 2 2 1 rRNA-processing protein Efg1 TM1586_NiRdase PF14512.6 EMG46564.1 - 0.044 13.3 0.4 0.09 12.3 0.4 1.5 1 0 0 1 1 1 0 Putative TM nitroreductase PhaP_Bmeg PF09602.10 EMG46564.1 - 0.061 13.3 5.9 0.18 11.7 3.8 2.0 1 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Mrpl_C PF18502.1 EMG46564.1 - 0.75 10.1 11.5 0.69 10.2 1.1 2.6 2 1 1 3 3 3 0 54S ribosomal protein L8 C-terminal domain Myb_DNA-bind_4 PF13837.6 EMG46564.1 - 1.8 9.0 7.3 13 6.2 2.0 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 EMG46564.1 - 2.5 8.8 10.4 4.9 7.9 2.3 2.6 1 1 1 2 2 2 0 Protein of unknown function, DUF573 MMR_HSR1_Xtn PF16897.5 EMG46565.1 - 8.7e-36 122.2 1.3 1.6e-35 121.3 1.3 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EMG46565.1 - 3.4e-20 72.2 0.1 7.1e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EMG46565.1 - 9.6e-20 70.4 0.0 2.1e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EMG46565.1 - 1.2e-12 47.7 0.0 2.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EMG46565.1 - 0.00074 19.6 0.8 0.033 14.2 0.0 2.4 1 1 1 2 2 2 1 Dynamin family MeaB PF03308.16 EMG46565.1 - 0.11 11.5 0.8 1.2 8.1 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 EMG46565.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Dynamitin PF04912.14 EMG46566.1 - 2.2e-29 103.0 28.0 8.9e-24 84.5 17.1 2.0 1 1 1 2 2 2 2 Dynamitin Spc7 PF08317.11 EMG46566.1 - 0.0022 16.9 16.0 0.0044 16.0 12.2 2.3 2 0 0 2 2 2 1 Spc7 kinetochore protein Fe-ADH PF00465.19 EMG46566.1 - 0.019 13.8 0.0 0.24 10.2 0.0 2.1 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase DHR10 PF18595.1 EMG46566.1 - 0.17 11.9 21.4 0.071 13.2 3.8 3.8 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Fzo_mitofusin PF04799.13 EMG46566.1 - 0.43 10.1 14.9 0.54 9.8 0.5 3.0 3 0 0 3 3 3 0 fzo-like conserved region DASH_Dam1 PF08653.10 EMG46566.1 - 1.6 8.6 7.7 37 4.2 0.1 4.8 4 1 1 5 5 5 0 DASH complex subunit Dam1 rRNA_proc-arch PF13234.6 EMG46566.1 - 1.7 8.5 17.0 16 5.3 17.0 2.7 1 1 0 1 1 1 0 rRNA-processing arch domain ABC_tran_CTD PF16326.5 EMG46566.1 - 1.8 8.9 18.5 3.2 8.1 2.4 4.3 4 1 0 4 4 4 0 ABC transporter C-terminal domain Dynein_C PF18199.1 EMG46566.1 - 2 7.5 6.7 9.3 5.4 6.6 2.2 1 1 0 1 1 1 0 Dynein heavy chain C-terminal domain DUF1664 PF07889.12 EMG46566.1 - 3 7.9 14.6 4.4 7.4 1.9 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) PCRF PF03462.18 EMG46566.1 - 5.5 6.8 14.3 1.8 8.4 0.4 3.1 2 1 1 3 3 3 0 PCRF domain Aldedh PF00171.22 EMG46567.1 - 1.7e-106 356.5 0.0 2.2e-106 356.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 EMG46567.1 - 0.021 14.8 0.7 0.052 13.6 0.7 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DnaJ_CXXCXGXG PF00684.19 EMG46568.1 - 7.9e-06 26.1 13.9 0.043 14.2 9.3 2.8 2 1 0 2 2 2 2 DnaJ central domain Spt4 PF06093.13 EMG46568.1 - 0.0043 17.1 0.1 0.0043 17.1 0.1 3.1 3 0 0 3 3 3 1 Spt4/RpoE2 zinc finger DZR PF12773.7 EMG46568.1 - 0.039 14.0 11.8 0.33 11.0 1.6 3.4 3 0 0 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EMG46568.1 - 6.3 6.9 13.5 12 6.0 1.2 3.0 2 1 1 3 3 3 0 zinc-ribbons Cytochrom_c3_2 PF14537.6 EMG46568.1 - 8.6 6.9 8.7 7.2 7.2 6.1 2.3 1 1 1 2 2 2 0 Cytochrome c3 DNA_pol_E_B PF04042.16 EMG46569.1 - 1.5e-33 115.9 0.0 2.6e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EMG46569.1 - 7.2e-32 110.2 0.1 1.5e-31 109.2 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Peptidase_S74 PF13884.6 EMG46569.1 - 0.0092 16.3 0.0 0.037 14.4 0.0 2.0 2 0 0 2 2 2 1 Chaperone of endosialidase DEAD PF00270.29 EMG46570.1 - 2.8e-48 164.0 1.1 5.2e-48 163.1 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG46570.1 - 1.3e-25 89.8 0.1 3.1e-24 85.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EMG46570.1 - 4.8e-16 58.7 0.2 9.2e-16 57.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EMG46570.1 - 0.00026 21.0 0.0 0.00067 19.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EMG46570.1 - 2.2 8.5 5.3 0.99 9.7 0.9 2.8 4 1 0 4 4 4 0 AAA domain Alpha-amylase PF00128.24 EMG46571.1 - 1.4e-121 406.2 1.6 1.4e-121 406.2 1.6 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EMG46571.1 - 1.4e-05 24.4 0.1 8.3e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 EMG46571.1 - 0.0001 22.4 0.0 0.00082 19.5 0.0 2.3 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain Sugar_tr PF00083.24 EMG46572.1 - 4.5e-08 32.4 0.8 5.7e-08 32.0 0.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG46572.1 - 0.0016 17.4 0.1 0.0016 17.4 0.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.16 EMG46572.1 - 0.058 11.6 0.6 0.084 11.1 0.6 1.2 1 0 0 1 1 1 0 BT1 family Aldo_ket_red PF00248.21 EMG46573.1 - 3.7e-51 174.1 0.0 5.1e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family TauD PF02668.16 EMG46574.1 - 1.5e-24 87.3 0.0 2.3e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EMG46574.1 - 1e-15 58.1 0.2 2e-15 57.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) MULE PF10551.9 EMG46574.1 - 0.058 13.8 0.0 0.15 12.5 0.0 1.7 2 0 0 2 2 2 0 MULE transposase domain tRNA-synt_1g PF09334.11 EMG46576.1 - 1.9e-157 524.0 1.2 2.5e-157 523.7 1.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.10 EMG46576.1 - 8.2e-12 45.7 0.2 2.4e-11 44.2 0.2 1.8 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1 PF00133.22 EMG46576.1 - 2.9e-07 29.2 0.1 0.00057 18.3 0.0 2.8 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) EKLF_TAD1 PF16832.5 EMG46576.1 - 0.027 14.3 0.1 0.05 13.5 0.1 1.4 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Anticodon_1 PF08264.13 EMG46576.1 - 0.083 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Amidase PF01425.21 EMG46577.1 - 7.9e-91 305.3 0.0 9e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Amidase GTP_cyclohydroI PF01227.22 EMG46578.1 - 5.6e-77 257.2 0.3 6.9e-77 256.9 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EMG46578.1 - 0.0001 22.4 0.0 0.00037 20.6 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein RNB PF00773.19 EMG46579.1 - 2e-66 224.5 3.4 3.8e-66 223.6 3.4 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EMG46579.1 - 4e-25 87.7 0.0 8.6e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EMG46579.1 - 6.5e-23 80.9 0.0 1.9e-22 79.4 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 EMG46579.1 - 7.9e-06 25.9 0.0 0.0025 17.9 0.0 2.8 2 0 0 2 2 2 1 Cold shock domain OB_RNB PF08206.11 EMG46579.1 - 0.0026 17.4 0.1 1.5 8.5 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease B OB domain Rrp44_CSD1 PF17216.3 EMG46579.1 - 0.0076 16.0 0.9 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EMG46579.1 - 0.022 14.7 0.0 0.078 12.9 0.0 1.9 1 0 0 1 1 1 0 S1 domain zf-H2C2_2 PF13465.6 EMG46580.1 - 6.7e-08 32.6 18.5 0.00037 20.8 2.9 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EMG46580.1 - 1.9e-07 31.1 15.0 0.0021 18.4 1.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG46580.1 - 0.00049 20.7 12.2 0.16 12.9 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMG46580.1 - 0.29 11.5 2.3 0.51 10.7 1.2 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF685 PF05085.12 EMG46580.1 - 0.37 10.1 1.7 0.59 9.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF685) zf-C2H2_6 PF13912.6 EMG46580.1 - 0.51 10.4 2.4 14 5.8 1.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EMG46580.1 - 0.72 9.7 16.2 0.74 9.6 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain RRM_1 PF00076.22 EMG46581.1 - 3.3e-06 26.8 0.6 0.001 18.8 0.0 3.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.13 EMG46581.1 - 0.0023 18.1 15.8 0.0023 18.1 15.8 2.4 2 1 0 2 2 2 1 YL1 nuclear protein PolyA_pol_RNAbd PF12627.7 EMG46582.1 - 0.094 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Mucin-like PF16058.5 EMG46582.1 - 0.13 12.3 4.9 0.27 11.3 4.9 1.6 1 0 0 1 1 1 0 Mucin-like Hyr1 PF15789.5 EMG46583.1 - 7.5e-51 169.4 93.0 3.4e-10 39.3 7.2 8.2 8 0 0 8 8 8 8 Hyphally regulated cell wall GPI-anchored protein 1 Hyphal_reg_CWP PF11765.8 EMG46583.1 - 1.7e-20 73.2 0.1 2.5e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Pput2613-deam PF14427.6 EMG46583.1 - 0.0017 18.2 6.3 3.6 7.5 0.0 5.2 1 1 4 6 6 6 2 Pput_2613-like deaminase XFP PF03894.15 EMG46583.1 - 0.0045 16.7 0.0 0.95 9.2 0.0 3.6 2 2 0 3 3 3 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase DUF5628 PF18621.1 EMG46583.1 - 0.069 13.6 34.6 1.4 9.5 0.2 7.7 3 1 5 9 9 9 0 Family of unknown function (DUF5628) DUF5497 PF17601.2 EMG46583.1 - 0.19 12.1 0.1 3.6 8.0 0.0 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5497) LRR_8 PF13855.6 EMG46584.1 - 0.39 10.5 10.9 10 6.0 0.1 4.9 3 1 1 4 4 4 0 Leucine rich repeat TP6A_N PF04406.14 EMG46586.1 - 1.5e-12 47.3 0.3 3.3e-12 46.2 0.3 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF1542 PF07564.11 EMG46586.1 - 0.23 11.6 0.7 0.41 10.8 0.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Pantoate_transf PF02548.15 EMG46587.1 - 6e-106 353.6 0.1 7e-106 353.4 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EMG46587.1 - 1.5e-06 27.9 0.0 3.9e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase TPR_10 PF13374.6 EMG46587.1 - 0.15 12.0 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 EMG46588.1 - 0.0065 16.7 0.1 12 6.3 0.1 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain LRR_5 PF13306.6 EMG46588.1 - 0.0097 15.9 4.9 0.051 13.5 0.2 2.7 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) WD40 PF00400.32 EMG46588.1 - 0.019 15.8 0.2 0.12 13.3 0.0 2.5 2 1 0 2 2 2 0 WD domain, G-beta repeat LRR_8 PF13855.6 EMG46588.1 - 0.091 12.5 1.8 1.6 8.6 0.1 2.7 2 0 0 2 2 2 0 Leucine rich repeat Glyoxalase PF00903.25 EMG46589.1 - 2.3e-31 108.7 0.5 3.3e-15 56.4 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMG46589.1 - 1e-06 29.0 0.0 0.04 14.2 0.0 3.2 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 EMG46589.1 - 1.6e-05 25.0 0.1 0.22 11.6 0.0 3.4 3 1 1 4 4 4 2 CppA N-terminal Glyoxalase_2 PF12681.7 EMG46589.1 - 0.003 17.5 4.5 0.68 9.9 0.1 4.0 3 2 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EMG46589.1 - 0.077 13.8 0.0 1.1 10.1 0.0 2.7 2 2 0 2 2 2 0 Glyoxalase-like domain DUF1048 PF06304.11 EMG46589.1 - 0.096 13.2 0.3 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) PRT_C PF08372.10 EMG46589.1 - 0.1 12.4 0.0 4.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Glyoxalase_3 PF13468.6 EMG46589.1 - 0.11 12.6 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Glyoxalase-like domain ABC_tran PF00005.27 EMG46591.1 - 2.3e-44 151.3 5.3 2.9e-21 76.4 0.1 3.6 3 1 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EMG46591.1 - 3.2e-21 75.1 7.0 3.2e-21 75.1 7.0 3.6 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 EMG46591.1 - 2.2e-16 60.6 13.2 0.00011 22.1 0.2 5.4 5 1 1 6 6 6 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMG46591.1 - 5.4e-11 42.3 2.5 0.00017 21.1 0.2 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMG46591.1 - 4.9e-06 26.5 20.9 0.0082 15.9 3.5 4.5 4 1 0 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 EMG46591.1 - 7.8e-06 25.9 0.5 0.065 13.1 0.1 3.0 2 1 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EMG46591.1 - 8e-06 25.5 0.2 0.18 11.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 EMG46591.1 - 1.8e-05 25.0 2.7 0.11 12.8 0.2 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EMG46591.1 - 4.3e-05 24.1 1.7 0.079 13.5 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.6 EMG46591.1 - 5.1e-05 23.7 0.1 0.048 14.1 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMG46591.1 - 5.1e-05 23.6 2.5 0.34 11.2 0.1 3.7 3 2 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EMG46591.1 - 6.1e-05 23.1 0.0 0.12 12.5 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 EMG46591.1 - 9.6e-05 22.8 0.1 0.6 10.5 0.1 3.8 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EMG46591.1 - 0.00023 20.9 0.0 0.19 11.4 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.6 EMG46591.1 - 0.00037 20.3 0.5 0.42 10.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EMG46591.1 - 0.00069 20.2 33.8 0.1 13.1 0.0 5.2 5 0 0 5 5 5 2 AAA domain NACHT PF05729.12 EMG46591.1 - 0.00083 19.3 0.3 0.81 9.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_7 PF12775.7 EMG46591.1 - 0.003 17.1 0.4 1.3 8.5 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region ATP-synt_ab PF00006.25 EMG46591.1 - 0.0054 16.4 0.1 0.31 10.7 0.0 2.9 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 EMG46591.1 - 0.0054 16.8 0.1 0.91 9.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 EMG46591.1 - 0.0077 16.5 0.1 4.3 7.6 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EMG46591.1 - 0.0087 16.4 0.2 8.6 6.8 0.0 3.0 3 0 0 3 3 2 0 RNA helicase PduV-EutP PF10662.9 EMG46591.1 - 0.0088 15.8 0.1 5.7 6.7 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EMG46591.1 - 0.012 15.8 6.1 1.2 9.3 0.1 3.4 4 0 0 4 4 3 0 AAA domain Dynamin_N PF00350.23 EMG46591.1 - 0.02 14.9 0.4 0.02 14.9 0.4 3.8 3 1 1 4 4 4 0 Dynamin family TsaE PF02367.17 EMG46591.1 - 0.032 14.2 0.2 7 6.7 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 EMG46591.1 - 0.04 12.9 0.2 0.82 8.6 0.0 3.0 3 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EMG46591.1 - 0.062 12.8 0.0 14 5.2 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.22 EMG46591.1 - 0.27 10.9 3.6 19 4.8 0.2 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 EMG46591.1 - 0.36 10.8 2.0 3.6 7.6 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) UPF0184 PF03670.13 EMG46591.1 - 1.5 9.3 7.3 0.31 11.4 0.7 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Glutaredoxin PF00462.24 EMG46592.1 - 3.9e-16 59.0 0.0 5.7e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 EMG46592.1 - 0.004 17.2 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Inos-1-P_synth PF01658.17 EMG46592.1 - 0.0087 16.3 0.2 0.31 11.3 0.0 2.0 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase DSBA PF01323.20 EMG46592.1 - 0.0094 15.7 0.1 0.94 9.2 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain DUF836 PF05768.14 EMG46592.1 - 0.013 15.9 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EMG46592.1 - 0.085 13.3 0.1 0.12 12.8 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Svf1 PF08622.10 EMG46593.1 - 1e-64 217.5 0.5 1e-64 217.5 0.5 1.8 2 0 0 2 2 2 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 EMG46593.1 - 2.2e-62 209.8 1.7 2.2e-62 209.7 0.5 1.6 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Aldedh PF00171.22 EMG46594.1 - 2.1e-69 234.2 0.0 2.6e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_2 PF02230.16 EMG46595.1 - 2.7e-05 24.1 0.0 0.065 13.0 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EMG46595.1 - 0.0035 16.6 0.0 0.025 13.9 0.0 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EMG46595.1 - 0.013 15.2 0.0 0.035 13.8 0.0 2.0 1 1 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 EMG46595.1 - 0.018 15.7 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family ANAPC4_WD40 PF12894.7 EMG46596.1 - 2.7e-06 27.6 0.0 0.0049 17.1 0.0 4.1 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMG46596.1 - 3e-06 27.9 0.0 0.0033 18.2 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EMG46596.1 - 0.014 14.4 0.3 0.066 12.2 0.0 2.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EMG46596.1 - 0.033 13.2 0.3 0.8 8.7 0.1 2.4 1 1 1 2 2 2 0 Coatomer WD associated region NOA36 PF06524.12 EMG46596.1 - 0.037 13.3 6.9 0.067 12.5 6.9 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3275 PF11679.8 EMG46596.1 - 0.06 13.3 0.7 0.13 12.3 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) Myc_N PF01056.18 EMG46596.1 - 0.068 13.1 8.3 0.017 15.0 4.5 1.8 2 0 0 2 2 2 0 Myc amino-terminal region CSRNP_N PF16019.5 EMG46596.1 - 0.37 10.7 2.5 0.77 9.6 2.5 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus UCH PF00443.29 EMG46597.1 - 3e-45 154.7 0.5 3.9e-45 154.4 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMG46597.1 - 3.8e-11 43.1 9.9 1e-08 35.1 9.9 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EMG46597.1 - 9.5e-07 28.5 0.5 4e-06 26.5 0.5 2.0 1 0 0 1 1 1 1 Ubiquitin family DUF1690 PF07956.11 EMG46598.1 - 3.6e-44 150.6 2.2 4.1e-44 150.4 2.2 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DRE2_N PF16803.5 EMG46598.1 - 0.0094 16.2 0.2 0.012 15.9 0.2 1.1 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Romo1 PF10247.9 EMG46599.1 - 1.5e-27 95.7 10.9 2.1e-27 95.3 10.9 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Lactamase_B_2 PF12706.7 EMG46600.1 - 6.6e-30 104.1 0.0 9.1e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMG46600.1 - 1.4e-13 51.1 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Actin PF00022.19 EMG46601.1 - 1.3e-19 70.1 0.2 1.8e-13 49.9 0.0 3.8 4 1 0 4 4 4 2 Actin Actin_micro PF17003.5 EMG46601.1 - 1.8e-06 27.4 2.6 1.8e-06 27.4 2.6 2.9 2 1 0 2 2 2 1 Putative actin-like family MreB_Mbl PF06723.13 EMG46601.1 - 0.00035 19.5 0.0 0.0022 16.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EMG46601.1 - 0.038 14.4 1.3 0.12 12.8 1.3 2.0 1 1 0 1 1 1 0 Cell division protein FtsA Peptidase_C50 PF03568.17 EMG46602.1 - 4.2e-108 362.0 2.4 1.2e-107 360.5 0.0 2.8 3 0 0 3 3 3 1 Peptidase family C50 Ligase_CoA PF00549.19 EMG46602.1 - 7.4e-24 84.3 0.1 1.4e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase IGR PF09597.10 EMG46602.1 - 3.1e-21 75.2 0.3 1.7e-20 72.8 0.3 2.5 1 0 0 1 1 1 1 IGR protein motif Succ_CoA_lig PF13607.6 EMG46602.1 - 1.2e-05 25.1 0.0 3.4e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding PF02629.19 EMG46602.1 - 0.0049 17.5 1.0 0.012 16.3 1.0 1.7 1 0 0 1 1 1 1 CoA binding domain RSS_P20 PF11757.8 EMG46602.1 - 0.05 14.0 1.8 0.74 10.3 0.5 3.3 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain ISN1 PF06437.11 EMG46603.1 - 2.1e-179 596.7 0.0 2.4e-179 596.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase CIA30 PF08547.12 EMG46604.1 - 6.3e-44 149.8 0.0 8.6e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 EMG46604.1 - 0.0048 16.9 0.2 0.027 14.4 0.0 1.9 1 1 1 2 2 2 1 Surface glycan-binding protein B xyloglucan binding domain CBM_11 PF03425.13 EMG46604.1 - 0.061 13.2 0.2 0.094 12.6 0.2 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) NNMT_PNMT_TEMT PF01234.17 EMG46604.1 - 0.16 11.1 0.1 0.23 10.6 0.1 1.1 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family adh_short PF00106.25 EMG46605.1 - 5.2e-23 81.5 0.0 2e-21 76.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG46605.1 - 1.4e-13 51.0 0.0 4.1e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 EMG46605.1 - 0.0019 17.7 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EMG46605.1 - 0.0024 17.8 0.3 0.0051 16.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Orthopox_B11R PF07033.11 EMG46606.1 - 0.11 12.3 1.0 0.14 11.9 0.6 1.5 1 1 0 1 1 1 0 Orthopoxvirus B11R protein RNA_pol_Rpb2_6 PF00562.28 EMG46607.1 - 4e-127 424.5 0.0 7.7e-126 420.3 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EMG46607.1 - 3.3e-68 229.2 0.1 5e-68 228.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EMG46607.1 - 4.8e-48 163.3 0.0 1e-47 162.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EMG46607.1 - 1.6e-34 118.1 0.3 3.7e-34 117.0 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EMG46607.1 - 2.3e-24 85.3 0.1 5.1e-24 84.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EMG46607.1 - 2.5e-24 85.6 0.9 8.7e-24 83.9 0.9 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 EMG46607.1 - 2.7e-24 85.2 0.1 6.2e-24 84.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 MRNIP PF15749.5 EMG46607.1 - 0.022 15.4 0.3 0.022 15.4 0.3 1.9 2 0 0 2 2 2 0 MRN-interacting protein Ribosomal_L23 PF00276.20 EMG46608.1 - 1.2e-10 41.7 0.0 3.5e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L23 TB2_DP1_HVA22 PF03134.19 EMG46609.1 - 1.6e-10 40.7 2.8 1.3e-09 37.8 1.2 2.4 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Ribosomal_L13 PF00572.18 EMG46610.1 - 1e-44 151.8 0.1 1.3e-44 151.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 UBA PF00627.31 EMG46611.1 - 1.3e-05 25.0 0.0 3.7e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Say1_Mug180 PF10340.9 EMG46611.1 - 0.0043 16.0 0.3 0.0099 14.8 0.1 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase DUF1640 PF07798.11 EMG46611.1 - 0.048 13.7 4.0 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF2229 PF09989.9 EMG46611.1 - 0.078 12.6 0.4 0.15 11.7 0.4 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PRKG1_interact PF15898.5 EMG46611.1 - 0.78 10.7 10.2 0.095 13.6 1.1 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Vps5 PF09325.10 EMG46612.1 - 6.1e-08 32.5 8.7 1.4e-07 31.3 8.7 1.5 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EMG46612.1 - 0.0002 21.3 0.1 0.0002 21.3 0.1 2.4 2 1 0 2 2 2 1 PX domain PINIT PF14324.6 EMG46613.1 - 4.8e-16 59.4 1.1 1.4e-15 57.9 1.1 1.8 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EMG46613.1 - 0.00015 21.5 0.7 0.00034 20.3 0.7 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger DUF4686 PF15742.5 EMG46613.1 - 0.0034 16.6 4.3 0.0034 16.6 4.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4686) zf-Nse PF11789.8 EMG46613.1 - 0.033 14.0 0.5 0.033 14.0 0.5 2.8 2 1 1 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 EMG46613.1 - 0.21 11.5 1.5 0.39 10.6 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SHS2_Rpb7-N PF03876.17 EMG46614.1 - 2.4e-17 63.0 0.0 4e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EMG46614.1 - 8.4e-16 58.1 0.1 1.3e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EMG46614.1 - 0.041 14.1 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Sod_Fe_C PF02777.18 EMG46616.1 - 3.9e-31 107.3 0.7 3.9e-31 107.3 0.7 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EMG46616.1 - 2.8e-29 101.4 1.3 5e-29 100.6 1.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.7 EMG46616.1 - 0.097 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RVT_N PF13655.6 EMG46616.1 - 0.98 9.7 4.5 2.5 8.4 0.2 2.5 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase tRNA-synt_1d PF00750.19 EMG46617.1 - 4.9e-112 374.3 5.7 6.9e-112 373.8 5.7 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EMG46617.1 - 6.2e-31 107.0 0.6 1.6e-30 105.7 0.1 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EMG46617.1 - 0.0038 17.8 0.0 0.017 15.7 0.0 2.2 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Scm3 PF10384.9 EMG46617.1 - 0.054 13.2 0.7 0.23 11.3 0.2 2.3 2 0 0 2 2 2 0 Centromere protein Scm3 Fmp27_GFWDK PF10347.9 EMG46618.1 - 0.043 13.9 0.0 0.048 13.8 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ribosomal_S21e PF01249.18 EMG46619.1 - 1.4e-39 134.1 0.1 1.5e-39 133.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Ribosomal_S5 PF00333.20 EMG46620.1 - 1.1e-26 92.6 4.0 2.1e-26 91.7 3.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EMG46620.1 - 5.9e-23 80.1 0.1 1e-22 79.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain CoA_binding_3 PF13727.6 EMG46620.1 - 0.03 14.3 0.1 0.11 12.5 0.0 1.8 1 1 1 2 2 2 0 CoA-binding domain DUF5353 PF17304.2 EMG46621.1 - 0.0015 18.3 0.7 0.0028 17.3 0.7 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5353) BPD_transp_2 PF02653.16 EMG46621.1 - 0.026 13.7 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component V-ATPase_G_2 PF16999.5 EMG46621.1 - 0.048 14.1 5.3 0.082 13.3 5.1 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF883 PF05957.13 EMG46621.1 - 0.13 12.9 7.5 0.92 10.2 7.5 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ApoO PF09769.9 EMG46621.1 - 0.18 11.7 1.3 0.62 10.0 0.1 2.0 1 1 1 2 2 2 0 Apolipoprotein O ATP-synt_B PF00430.18 EMG46621.1 - 1.4 9.0 9.7 0.41 10.7 6.2 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) SMBP PF16785.5 EMG46621.1 - 1.9 8.7 6.9 0.91 9.8 4.7 1.6 2 0 0 2 2 2 0 Small metal-binding protein tRNA_U5-meth_tr PF05958.11 EMG46622.1 - 1.3e-23 83.6 0.6 1.6e-22 80.0 0.6 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EMG46622.1 - 1.3e-09 38.0 0.0 3.1e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.20 EMG46622.1 - 2.1e-07 30.8 0.0 6.2e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 TRAM domain Methyltransf_25 PF13649.6 EMG46622.1 - 2.6e-06 28.1 0.0 6.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EMG46622.1 - 4.9e-06 26.2 0.1 1.1e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EMG46622.1 - 0.00014 21.4 0.1 0.00025 20.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 EMG46622.1 - 0.00018 21.3 0.1 0.00043 20.1 0.1 1.7 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EMG46622.1 - 0.00028 20.5 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EMG46622.1 - 0.00099 19.7 0.0 0.0026 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMG46622.1 - 0.034 13.5 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCR1_C PF12550.8 EMG46623.1 - 3.5e-25 88.1 2.6 7.9e-25 87.0 2.6 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes FlaC_arch PF05377.11 EMG46623.1 - 0.12 12.7 2.7 1.3 9.4 0.3 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Hrs_helical PF12210.8 EMG46623.1 - 0.16 12.6 4.9 0.14 12.7 2.1 2.3 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Occludin_ELL PF07303.13 EMG46623.1 - 0.16 12.7 0.1 0.16 12.7 0.1 3.4 4 0 0 4 4 4 0 Occludin homology domain NPV_P10 PF05531.12 EMG46623.1 - 0.28 11.7 4.1 5.2 7.6 4.1 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EMG46623.1 - 1 9.7 5.7 4.8 7.5 2.9 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DTHCT PF08070.11 EMG46623.1 - 1.4 9.7 13.9 0.062 14.0 2.9 2.9 3 0 0 3 3 3 0 DTHCT (NUC029) region PAP2 PF01569.21 EMG46624.1 - 4.4e-18 65.4 4.1 4.4e-18 65.4 4.1 2.2 3 0 0 3 3 3 1 PAP2 superfamily DUF212 PF02681.14 EMG46624.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Divergent PAP2 family PAP2_3 PF14378.6 EMG46624.1 - 0.21 11.3 6.2 0.63 9.7 6.2 1.8 1 1 0 1 1 1 0 PAP2 superfamily Fer4_5 PF12801.7 EMG46624.1 - 3.7 7.6 5.6 0.6 10.1 0.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Ras PF00071.22 EMG46625.1 - 7.9e-45 152.4 0.0 1.3e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG46625.1 - 1.5e-22 80.1 0.0 4.7e-22 78.5 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG46625.1 - 6.4e-07 29.0 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 EMG46625.1 - 0.14 11.7 0.2 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region SCP2 PF02036.17 EMG46626.1 - 2.9e-21 75.8 0.4 3.2e-21 75.7 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EMG46626.1 - 0.00015 22.0 0.1 0.00019 21.7 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ABC1 PF03109.16 EMG46627.1 - 5.9e-30 103.9 0.0 1.6e-29 102.5 0.0 1.8 2 0 0 2 2 2 1 ABC1 family FUSC_2 PF13515.6 EMG46628.1 - 3.9e-33 114.3 7.6 3.9e-33 114.3 7.6 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EMG46628.1 - 7.1e-14 52.2 2.6 7.6e-11 42.3 0.1 2.4 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC PF04632.12 EMG46628.1 - 9.8e-05 21.1 3.5 0.003 16.2 2.8 2.4 2 1 0 2 2 2 2 Fusaric acid resistance protein family DUF1759 PF03564.15 EMG46628.1 - 0.027 14.4 0.4 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) SprT-like PF10263.9 EMG46628.1 - 0.036 13.9 0.1 0.084 12.7 0.1 1.5 1 0 0 1 1 1 0 SprT-like family zf-CCCH_2 PF14608.6 EMG46629.1 - 2.2e-19 69.1 73.6 1.8e-05 25.0 5.9 7.4 7 0 0 7 7 7 7 RNA-binding, Nab2-type zinc finger Kv2channel PF03521.14 EMG46629.1 - 0.03 13.7 4.3 0.048 13.0 4.3 1.2 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel DUF2508 PF10704.9 EMG46629.1 - 1.7 8.9 5.6 0.6 10.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Glyco_transf_8 PF01501.20 EMG46630.1 - 7.7e-18 65.0 1.3 1.6e-11 44.3 0.1 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 8 Zip PF02535.22 EMG46630.1 - 1.1 8.4 9.3 1.8 7.7 9.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter IL3 PF02059.15 EMG46630.1 - 1.1 9.3 3.3 18 5.4 0.2 3.3 3 0 0 3 3 3 0 Interleukin-3 V_ATPase_I PF01496.19 EMG46630.1 - 4.1 5.2 4.6 6.2 4.6 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family dUTPase PF00692.19 EMG46631.1 - 1.7e-46 157.1 0.0 2e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 dUTPase DEAD PF00270.29 EMG46633.1 - 1.3e-46 158.6 0.8 1.3e-46 158.6 0.8 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG46633.1 - 1.9e-32 111.9 0.7 1.1e-30 106.2 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG46633.1 - 4.6e-09 36.5 0.0 7.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMG46633.1 - 4.3e-05 23.3 0.1 6.4e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMG46633.1 - 5e-05 23.7 0.6 8.4e-05 22.9 0.2 1.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMG46633.1 - 0.004 17.4 0.1 0.012 15.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 EMG46633.1 - 0.0048 16.3 0.0 0.0099 15.2 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 EMG46633.1 - 0.025 14.5 0.2 0.14 12.1 0.2 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.21 EMG46633.1 - 0.036 13.6 0.7 0.052 13.0 0.7 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain LETM1 PF07766.13 EMG46634.1 - 2.2e-101 338.7 3.0 4.1e-101 337.8 3.0 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 EMG46634.1 - 0.016 14.9 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 SAP domain UPF0154 PF03672.13 EMG46634.1 - 0.11 12.5 1.5 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Septin PF00735.18 EMG46635.1 - 1.6e-91 306.5 5.9 2.7e-90 302.4 5.9 2.4 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EMG46635.1 - 5.2e-07 29.8 0.4 1.9e-06 27.9 0.4 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMG46635.1 - 9.7e-06 25.3 2.2 0.00029 20.5 0.2 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 EMG46635.1 - 8.6e-05 21.8 0.3 0.00025 20.2 0.1 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 EMG46635.1 - 0.00034 20.5 0.9 0.007 16.3 0.1 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EMG46635.1 - 0.00049 20.4 0.1 0.0026 18.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 EMG46635.1 - 0.00077 19.6 6.2 0.0035 17.4 0.9 3.2 2 1 0 2 2 2 1 Dynamin family AIG1 PF04548.16 EMG46635.1 - 0.0013 18.2 0.7 0.066 12.5 0.2 2.8 1 1 1 2 2 2 1 AIG1 family AAA_24 PF13479.6 EMG46635.1 - 0.0031 17.3 0.1 0.0077 16.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 EMG46635.1 - 0.0034 17.6 0.2 0.022 15.0 0.2 2.2 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 EMG46635.1 - 0.0039 16.7 0.1 0.0039 16.7 0.1 1.8 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_7 PF12775.7 EMG46635.1 - 0.006 16.1 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region NB-ARC PF00931.22 EMG46635.1 - 0.0094 15.2 0.0 0.026 13.7 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EMG46635.1 - 0.018 15.4 1.2 0.089 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Synaptobrevin PF00957.21 EMG46635.1 - 0.028 14.2 1.1 0.078 12.8 1.1 1.7 1 0 0 1 1 1 0 Synaptobrevin RNA_helicase PF00910.22 EMG46635.1 - 0.054 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Ras PF00071.22 EMG46635.1 - 0.056 13.0 0.5 0.42 10.2 0.2 2.3 1 1 0 2 2 2 0 Ras family MobB PF03205.14 EMG46635.1 - 0.065 13.1 0.1 0.43 10.5 0.0 2.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 EMG46635.1 - 0.069 13.3 1.2 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain IGF2_C PF08365.11 EMG46635.1 - 0.12 12.4 0.7 23 5.1 1.1 2.7 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide ABC_tran PF00005.27 EMG46635.1 - 0.22 12.0 0.0 0.22 12.0 0.0 2.7 2 1 0 2 2 1 0 ABC transporter ATP_bind_1 PF03029.17 EMG46635.1 - 2.6 7.7 7.2 1.7 8.3 1.6 2.7 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein YjeF_N PF03853.15 EMG46636.1 - 1.8e-35 122.4 0.0 2.1e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Pyr_redox_3 PF13738.6 EMG46636.1 - 0.21 10.8 0.0 0.44 9.7 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4941 PF16299.5 EMG46637.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4941) Trypan_PARP PF05887.11 EMG46638.1 - 0.84 9.6 7.9 1.6 8.7 7.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PITH PF06201.13 EMG46640.1 - 2.1e-29 102.7 3.0 3.8e-29 101.9 3.0 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EMG46640.1 - 2.2e-22 79.0 0.1 5.9e-22 77.6 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMG46640.1 - 2.9e-09 37.3 0.1 4.4e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMG46640.1 - 1.9e-08 34.5 0.3 1.6e-07 31.6 0.1 2.7 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EMG46640.1 - 1e-07 31.8 0.0 2.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EMG46640.1 - 1.5e-06 28.3 0.1 5.5e-06 26.5 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EMG46640.1 - 6.4e-05 22.9 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EMG46640.1 - 0.00027 20.4 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EMG46640.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Redoxin Glutaredoxin PF00462.24 EMG46640.1 - 0.031 14.5 0.0 0.078 13.2 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin ArfGap PF01412.18 EMG46641.1 - 0.018 15.1 0.1 0.082 13.0 0.0 2.1 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf HEAT_EZ PF13513.6 EMG46642.1 - 4.6e-19 68.5 9.5 3.8e-09 36.9 0.0 9.1 9 1 0 9 9 9 3 HEAT-like repeat HEAT PF02985.22 EMG46642.1 - 3.5e-18 64.1 17.8 0.00023 21.1 0.0 13.6 15 0 0 15 15 15 2 HEAT repeat HEAT_2 PF13646.6 EMG46642.1 - 8.5e-13 48.5 5.7 0.00033 21.0 0.1 7.5 4 3 4 8 8 8 3 HEAT repeats IBN_N PF03810.19 EMG46642.1 - 9.1e-09 35.1 3.9 1.4e-08 34.5 0.7 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.23 EMG46642.1 - 2.9e-07 30.3 14.7 0.00014 21.8 0.1 7.4 9 0 0 9 9 8 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EMG46642.1 - 1.3e-06 28.5 9.1 0.00034 20.7 0.1 4.5 3 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EMG46642.1 - 0.00011 21.9 1.1 2.9 7.4 0.0 4.5 3 2 2 5 5 5 2 CLASP N terminal TIP120 PF08623.10 EMG46642.1 - 0.0015 18.4 2.4 0.006 16.4 0.0 2.9 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) NUC173 PF08161.12 EMG46642.1 - 0.0028 17.3 0.2 1.6 8.4 0.1 3.1 3 0 0 3 3 3 2 NUC173 domain HEAT_PBS PF03130.16 EMG46642.1 - 0.059 14.1 6.4 14 6.7 0.1 6.2 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat RIX1 PF08167.12 EMG46642.1 - 0.072 12.8 3.8 0.29 10.8 0.4 3.9 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis Ecm29 PF13001.7 EMG46642.1 - 2.1 6.9 8.6 6.6 5.3 0.1 4.0 3 1 2 5 5 5 0 Proteasome stabiliser Glyco_hydro_72 PF03198.14 EMG46643.1 - 1e-126 422.4 3.2 1.4e-126 422.1 3.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EMG46643.1 - 0.00087 19.9 0.4 0.0023 18.6 0.4 1.7 1 0 0 1 1 1 1 X8 domain PBP1_TM PF14812.6 EMG46643.1 - 0.22 11.9 3.5 0.5 10.8 3.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Paf1 PF03985.13 EMG46643.1 - 8.3 5.3 12.4 25 3.7 11.6 1.8 2 0 0 2 2 2 0 Paf1 Ribosomal_L26 PF16906.5 EMG46644.1 - 1.2e-35 121.8 3.1 1.5e-35 121.5 3.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EMG46644.1 - 0.00077 19.3 0.9 0.0012 18.7 0.3 1.7 2 0 0 2 2 2 1 KOW motif TP2 PF01254.18 EMG46644.1 - 0.14 12.8 2.9 0.074 13.7 1.3 1.4 2 0 0 2 2 2 0 Nuclear transition protein 2 6PF2K PF01591.18 EMG46645.1 - 3.2e-60 203.2 0.1 4.4e-60 202.8 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EMG46645.1 - 4.4e-20 72.2 0.0 6.5e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 EMG46645.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EMG46645.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EMG46645.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 EMG46645.1 - 0.05 14.2 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1262 PF06880.11 EMG46645.1 - 0.091 13.2 0.0 0.57 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1262) IstB_IS21 PF01695.17 EMG46645.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ZnuA PF01297.17 EMG46645.1 - 0.15 11.4 0.9 0.69 9.3 0.9 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic Gon7 PF08738.10 EMG46646.1 - 4.7e-31 107.1 2.1 5.1e-31 106.9 2.1 1.0 1 0 0 1 1 1 1 Gon7 family ATP12 PF07542.11 EMG46647.1 - 2.7e-32 111.6 0.1 4.5e-32 110.8 0.1 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein SMK-1 PF04802.15 EMG46648.1 - 2.2e-54 184.2 11.8 3.5e-54 183.6 8.4 2.5 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 EMG46648.1 - 0.033 14.1 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 WH1 domain adh_short_C2 PF13561.6 EMG46649.1 - 1.4e-42 145.9 1.2 1.7e-42 145.6 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMG46649.1 - 9.8e-34 116.5 1.3 1.3e-33 116.2 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG46649.1 - 4.6e-09 36.4 0.8 7.2e-09 35.8 0.8 1.2 1 0 0 1 1 1 1 KR domain DUF5350 PF17299.2 EMG46649.1 - 0.14 12.7 0.0 0.44 11.1 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5350) Glucan_synthase PF02364.15 EMG46650.1 - 0 1334.1 0.0 0 1334.1 0.0 2.3 3 0 0 3 3 3 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EMG46650.1 - 1.1e-41 142.2 0.2 1.1e-41 142.2 0.2 2.0 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF1751 PF08551.10 EMG46651.1 - 6.2e-24 84.4 3.4 6.2e-24 84.4 3.4 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EMG46651.1 - 0.003 17.6 9.0 0.003 17.6 9.0 1.6 2 0 0 2 2 2 1 Rhomboid family Glyco_transf_34 PF05637.12 EMG46652.1 - 2.3e-55 187.9 2.2 3.9e-55 187.2 2.2 1.4 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Lactamase_B PF00753.27 EMG46653.1 - 0.0023 18.0 1.0 0.0098 15.9 0.3 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF1410 PF07198.11 EMG46653.1 - 0.039 14.5 5.1 27 5.3 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1410) Arf PF00025.21 EMG46654.1 - 1.3e-30 106.1 0.3 1.6e-30 105.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMG46654.1 - 4.7e-07 30.1 0.0 6.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EMG46654.1 - 1.7e-05 24.3 0.1 2.3e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EMG46654.1 - 0.00029 20.4 0.0 0.00032 20.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 EMG46654.1 - 0.00068 19.3 0.0 0.00081 19.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EMG46654.1 - 0.0012 18.1 0.6 0.0022 17.2 0.5 1.5 1 1 0 1 1 1 1 G-protein alpha subunit cobW PF02492.19 EMG46654.1 - 0.047 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EMG46654.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Glyco_hydro_17 PF00332.18 EMG46656.1 - 6.4e-08 32.5 1.1 2.5e-07 30.6 0.2 1.9 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Serglycin PF04360.12 EMG46656.1 - 3.3 7.6 8.7 0.69 9.9 4.1 2.1 3 0 0 3 3 3 0 Serglycin AA_permease PF00324.21 EMG46657.1 - 4e-81 273.0 47.2 4.7e-81 272.8 47.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG46657.1 - 1e-24 87.2 52.7 1.4e-24 86.7 52.7 1.1 1 0 0 1 1 1 1 Amino acid permease S_4TM PF18159.1 EMG46657.1 - 1.5 8.0 0.0 1.5 8.0 0.0 2.4 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain DUF1640 PF07798.11 EMG46658.1 - 4.3e-48 163.7 14.1 4.3e-48 163.7 14.1 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF1640) V-SNARE_C PF12352.8 EMG46658.1 - 1.8e-09 37.7 0.5 7e-09 35.9 0.5 2.1 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EMG46658.1 - 3.6e-05 23.6 0.1 3.6e-05 23.6 0.1 3.7 2 1 1 4 4 4 1 Sec20 BORCS6 PF10157.9 EMG46658.1 - 0.01 16.0 4.9 0.012 15.8 0.8 2.3 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 Baculo_PEP_C PF04513.12 EMG46658.1 - 0.019 15.0 13.0 0.022 14.8 1.9 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus LysM PF01476.20 EMG46658.1 - 0.048 13.7 0.1 1.1 9.3 0.0 2.9 3 0 0 3 3 3 0 LysM domain Sigma70_r4 PF04545.16 EMG46658.1 - 0.073 12.6 0.3 0.21 11.1 0.3 1.9 1 1 0 1 1 1 0 Sigma-70, region 4 Prp19 PF08606.11 EMG46658.1 - 0.1 12.6 4.1 4.8 7.2 0.3 3.5 3 0 0 3 3 3 0 Prp19/Pso4-like HALZ PF02183.18 EMG46658.1 - 1.2 9.4 10.1 0.09 13.0 2.4 3.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper KxDL PF10241.9 EMG46658.1 - 9.2 6.6 20.0 4.3 7.7 1.5 4.4 2 1 2 4 4 4 0 Uncharacterized conserved protein AA_permease PF00324.21 EMG46659.1 - 1e-114 383.8 38.1 1.2e-114 383.5 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG46659.1 - 7.9e-33 113.9 38.9 1.4e-32 113.1 38.6 1.4 1 1 0 1 1 1 1 Amino acid permease DUF3382 PF11862.8 EMG46659.1 - 1.1 9.6 5.3 0.43 10.9 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) DUF2207 PF09972.9 EMG46659.1 - 1.3 7.7 0.0 1.3 7.7 0.0 4.5 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) eIF2A PF08662.11 EMG46660.1 - 6.7e-79 264.3 0.0 8e-77 257.5 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EMG46660.1 - 0.022 13.8 0.1 0.15 11.0 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region WD40 PF00400.32 EMG46660.1 - 0.074 14.0 0.2 16 6.5 0.1 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat OTU PF02338.19 EMG46661.1 - 5.7e-10 39.8 0.0 1.1e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EMG46661.1 - 0.004 16.6 0.0 0.19 11.1 0.0 2.6 3 0 0 3 3 3 2 Peptidase C65 Otubain zf-C2H2_jaz PF12171.8 EMG46662.1 - 3.5e-09 36.7 2.4 7.4e-09 35.7 2.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding ALP_N PF17989.1 EMG46662.1 - 0.018 15.2 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Actin like proteins N terminal domain IPT PF01745.16 EMG46662.1 - 0.038 13.4 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Isopentenyl transferase zf-H2C2_2 PF13465.6 EMG46662.1 - 1.1 9.8 4.3 4.4 7.9 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Ribosomal_L16 PF00252.18 EMG46663.1 - 1.5e-41 141.5 0.1 1.9e-41 141.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PMM PF03332.13 EMG46665.1 - 1.1e-114 381.7 1.1 1.3e-114 381.5 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EMG46665.1 - 5e-08 33.0 0.0 5.9e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EMG46665.1 - 0.00012 21.7 0.0 0.054 13.0 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 EMG46665.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RCC1 PF00415.18 EMG46666.1 - 6.9e-18 65.0 0.0 0.00037 21.1 0.0 6.2 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMG46666.1 - 1.7e-15 56.4 4.7 1.3e-06 28.0 0.5 5.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat YcxB PF14317.6 EMG46666.1 - 0.026 14.2 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 0 YcxB-like protein tRNA-synt_2d PF01409.20 EMG46667.1 - 6.7e-89 297.6 0.0 9.2e-89 297.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EMG46667.1 - 6.8e-11 42.3 0.2 6.8e-11 42.3 0.2 2.6 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EMG46667.1 - 8.7e-10 38.4 0.0 2.4e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EMG46667.1 - 0.00025 20.2 0.1 0.0064 15.6 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EMG46667.1 - 0.00027 21.0 0.0 0.00052 20.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 EMG46667.1 - 0.0018 18.2 4.9 0.0018 18.2 4.9 2.4 2 0 0 2 2 2 1 PheRS DNA binding domain 2 DUF1642 PF07852.11 EMG46667.1 - 0.11 13.1 1.4 0.15 12.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1642) DUF2150 PF09920.9 EMG46667.1 - 0.2 11.6 4.8 0.25 11.3 0.5 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) Cellulase PF00150.18 EMG46668.1 - 1.8e-14 53.8 14.2 6.3e-14 52.1 14.2 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1911 PF08929.10 EMG46668.1 - 0.24 12.2 1.8 4.7 8.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1911) Homoserine_dh PF00742.19 EMG46669.1 - 8.4e-52 175.6 0.0 1.1e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EMG46669.1 - 2.7e-21 76.4 0.0 4.5e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IML1 PF12257.8 EMG46670.1 - 6.7e-102 340.4 0.1 9.9e-102 339.9 0.1 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EMG46670.1 - 3.1e-25 88.0 0.2 8.2e-25 86.7 0.2 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SNO PF01174.19 EMG46671.1 - 2.6e-65 219.8 0.0 1.6e-63 214.0 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EMG46671.1 - 5.2e-08 32.7 0.0 1.9e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EMG46671.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family BPL_N PF09825.9 EMG46671.1 - 0.057 12.5 0.0 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal ThiJ_like PF17124.5 EMG46671.1 - 0.073 12.7 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like GATase PF00117.28 EMG46671.1 - 0.13 12.0 0.0 0.85 9.4 0.0 2.1 1 1 0 1 1 1 0 Glutamine amidotransferase class-I SOR_SNZ PF01680.17 EMG46672.1 - 9.7e-104 345.6 5.8 9.7e-104 345.6 5.8 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 EMG46672.1 - 1.5e-10 40.9 0.5 3.4e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EMG46672.1 - 0.0001 21.5 0.1 0.079 12.0 0.0 2.7 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) NanE PF04131.14 EMG46672.1 - 0.0016 17.7 0.4 0.11 11.7 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 EMG46672.1 - 0.0083 16.2 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 EMG46672.1 - 0.012 15.1 0.0 0.08 12.4 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein IGPS PF00218.21 EMG46672.1 - 0.014 14.6 0.4 0.096 11.8 0.0 2.3 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.15 EMG46672.1 - 0.021 14.2 1.8 0.2 11.0 0.2 2.5 2 1 0 2 2 2 0 Nitronate monooxygenase IMPDH PF00478.25 EMG46672.1 - 0.026 13.5 0.7 0.035 13.1 0.7 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EMG46672.1 - 0.027 13.5 0.2 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase TMP-TENI PF02581.17 EMG46672.1 - 0.045 13.1 0.5 3.1 7.1 0.1 2.6 2 1 0 2 2 2 0 Thiamine monophosphate synthase Peptidase_S66C PF17676.1 EMG46672.1 - 0.065 13.8 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain CLTH PF10607.9 EMG46672.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain AA_permease_2 PF13520.6 EMG46673.1 - 4.9e-65 220.0 54.0 5.9e-65 219.7 54.0 1.0 1 0 0 1 1 1 1 Amino acid permease TrbC PF04956.13 EMG46673.1 - 0.16 12.2 0.2 0.16 12.2 0.2 4.1 3 2 1 4 4 4 0 TrbC/VIRB2 family DUF2830 PF11125.8 EMG46673.1 - 2.9 7.9 5.7 0.41 10.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) Rab5ip PF07019.12 EMG46676.1 - 0.043 14.4 0.2 0.052 14.1 0.2 1.1 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) LicD PF04991.13 EMG46677.1 - 5.7e-07 29.9 1.1 2.1e-05 24.8 0.0 4.5 4 1 1 5 5 5 2 LicD family LisH_2 PF16045.5 EMG46677.1 - 0.071 12.1 0.0 0.25 10.4 0.0 2.0 1 0 0 1 1 1 0 LisH LicD PF04991.13 EMG46678.1 - 8.2e-20 71.9 7.0 1.4e-17 64.7 2.8 4.0 4 1 1 5 5 5 2 LicD family Mgm101p PF06420.12 EMG46679.1 - 4.9e-85 283.3 0.0 7.2e-85 282.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MAS20 PF02064.15 EMG46681.1 - 7.3e-42 142.5 3.4 9e-42 142.2 3.4 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor zf-H2C2_2 PF13465.6 EMG46682.1 - 8e-06 26.0 4.0 8e-06 26.0 4.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EMG46682.1 - 0.0004 20.7 0.5 0.0004 20.7 0.5 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 EMG46682.1 - 0.0062 17.1 15.8 0.21 12.2 0.1 4.8 5 0 0 5 5 5 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EMG46682.1 - 0.033 15.0 8.8 0.083 13.8 0.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMG46682.1 - 0.06 13.6 0.5 0.41 11.0 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zap1_zf2 PF18217.1 EMG46682.1 - 0.73 9.9 11.5 0.11 12.6 1.2 3.1 3 0 0 3 3 3 0 Zap1 zinc finger 2 zf_ZIC PF18366.1 EMG46682.1 - 1.1 9.4 8.3 1.2 9.3 3.2 3.1 2 1 0 2 2 2 0 Zic proteins zinc finger domain ArsA_ATPase PF02374.15 EMG46683.1 - 2.1e-107 358.8 0.3 2.4e-107 358.6 0.3 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EMG46683.1 - 3e-08 33.8 0.7 9e-08 32.2 0.1 2.1 2 2 1 3 3 3 1 AAA domain CbiA PF01656.23 EMG46683.1 - 1.1e-07 31.9 0.8 8.6e-07 29.1 0.8 2.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EMG46683.1 - 3.2e-05 23.5 2.6 0.0071 15.8 1.2 2.8 2 1 1 3 3 3 2 NUBPL iron-transfer P-loop NTPase NB-ARC PF00931.22 EMG46683.1 - 0.0007 18.9 0.0 0.002 17.4 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain Fer4_NifH PF00142.18 EMG46683.1 - 0.0093 15.4 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 EMG46683.1 - 0.015 15.0 0.3 0.15 11.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 EMG46683.1 - 0.029 14.0 0.2 0.13 11.8 0.1 2.2 1 1 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EMG46683.1 - 0.032 13.5 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KorB PF08535.10 EMG46683.1 - 0.039 14.0 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 KorB domain AAA_25 PF13481.6 EMG46683.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.25 EMG46684.1 - 1.3e-31 108.5 2.6 1.2e-15 57.3 0.8 2.7 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EMG46684.1 - 1.5e-18 66.8 0.1 1.3e-17 63.7 0.0 2.3 2 0 0 2 2 2 1 BAH domain TFIIA PF03153.13 EMG46684.1 - 0.01 15.9 6.7 0.017 15.1 6.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tsi6 PF18660.1 EMG46684.1 - 0.29 11.2 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Tsi6 SIR2 PF02146.17 EMG46685.1 - 1.6e-28 99.8 0.0 3.4e-28 98.7 0.0 1.5 1 1 0 1 1 1 1 Sir2 family Glyco_transf_28 PF03033.20 EMG46685.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain DUF4144 PF13642.6 EMG46685.1 - 0.17 12.5 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 protein structure with unknown function HSP20 PF00011.21 EMG46687.1 - 0.026 14.7 0.1 0.082 13.1 0.0 1.7 1 1 0 1 1 1 0 Hsp20/alpha crystallin family Mitofilin PF09731.9 EMG46687.1 - 0.11 11.4 7.7 0.12 11.2 7.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SOG2 PF10428.9 EMG46687.1 - 0.12 11.6 12.0 0.13 11.4 12.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4834 PF16118.5 EMG46687.1 - 1.8 9.5 6.3 0.47 11.5 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) IHABP4_N PF16174.5 EMG46687.1 - 2.5 8.7 14.1 5.1 7.7 14.1 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DLH PF01738.18 EMG46688.1 - 5.5e-27 94.7 0.1 3.1e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family WD40 PF00400.32 EMG46688.1 - 2.4e-19 69.3 3.1 0.0021 18.9 0.2 6.7 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG46688.1 - 5.1e-11 42.7 0.2 0.0027 18.0 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain BAAT_C PF08840.11 EMG46688.1 - 0.0026 17.7 0.0 0.2 11.5 0.0 2.3 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal PQQ_2 PF13360.6 EMG46688.1 - 0.0028 17.3 0.1 0.0045 16.6 0.1 1.3 1 0 0 1 1 1 1 PQQ-like domain Peptidase_S9 PF00326.21 EMG46688.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family LIDHydrolase PF10230.9 EMG46688.1 - 0.02 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PQQ PF01011.21 EMG46688.1 - 0.039 13.9 1.1 0.55 10.3 0.0 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat Peptidase_S15 PF02129.18 EMG46688.1 - 0.045 13.3 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 EMG46688.1 - 0.15 12.1 2.1 6.1 6.9 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat 4F5 PF04419.14 EMG46689.1 - 6.7e-09 36.5 16.9 6.7e-09 36.5 16.9 2.4 2 1 0 2 2 2 1 4F5 protein family NAD_binding_4 PF07993.12 EMG46690.1 - 1.3e-71 240.8 0.0 2e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EMG46690.1 - 2.9e-67 227.1 0.0 4e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EMG46690.1 - 2.5e-13 50.2 0.0 1.6e-12 47.6 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 EMG46690.1 - 8.2e-10 38.5 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG46690.1 - 9.8e-08 31.3 0.0 3e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.20 EMG46690.1 - 3.3e-07 29.3 0.2 1.1e-05 24.3 0.2 2.7 1 1 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 EMG46690.1 - 2.1e-05 25.4 0.1 7.7e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 EMG46690.1 - 0.0037 16.7 0.0 0.0083 15.6 0.0 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMG46690.1 - 0.005 16.0 0.0 0.0085 15.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EMG46690.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family SNF2_N PF00176.23 EMG46691.1 - 6.9e-53 179.6 0.0 3.4e-52 177.3 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMG46691.1 - 1.1e-15 57.9 0.0 3.3e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EMG46691.1 - 1.9e-09 37.2 9.1 1.9e-09 37.2 9.1 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EMG46691.1 - 2e-07 31.2 1.1 4.2e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMG46691.1 - 6.9e-07 29.2 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 EMG46691.1 - 7e-06 25.8 8.9 7e-06 25.8 8.9 2.3 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMG46691.1 - 0.00044 20.3 8.9 0.00044 20.3 8.9 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EMG46691.1 - 0.00095 19.0 7.6 0.00095 19.0 7.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG46691.1 - 0.00097 19.1 5.0 0.00097 19.1 5.0 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EMG46691.1 - 0.0015 18.8 9.3 0.0015 18.8 9.3 2.2 2 0 0 2 2 1 1 Ring finger domain Zn_Tnp_IS91 PF14319.6 EMG46691.1 - 0.0055 16.7 9.6 0.031 14.3 1.5 2.5 2 0 0 2 2 2 2 Transposase zinc-binding domain zf-rbx1 PF12678.7 EMG46691.1 - 0.0058 16.9 5.1 0.0058 16.9 5.1 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EMG46691.1 - 0.0066 16.2 4.6 0.019 14.8 4.6 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DevR PF01905.16 EMG46691.1 - 0.0089 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 CRISPR-associated negative auto-regulator DevR/Csa2 zf-RING_6 PF14835.6 EMG46691.1 - 0.32 10.9 3.1 0.8 9.6 3.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF2393 PF09624.10 EMG46692.1 - 0.52 10.3 5.5 0.7 9.9 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2393) Vma12 PF11712.8 EMG46692.1 - 0.57 10.3 2.8 0.4 10.7 0.1 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PDEase_I PF00233.19 EMG46693.1 - 5.3e-54 183.5 3.6 8.3e-48 163.2 0.7 2.5 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Synaptobrevin PF00957.21 EMG46694.1 - 1.3e-14 53.7 0.3 2.2e-14 53.0 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EMG46694.1 - 6.9e-10 38.8 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain SAM_2 PF07647.17 EMG46695.1 - 1.6e-06 28.1 0.1 3.1e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EMG46695.1 - 0.046 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CHCH PF06747.13 EMG46696.1 - 1e-07 31.9 3.5 1.9e-07 31.0 3.5 1.5 1 0 0 1 1 1 1 CHCH domain Presenilin PF01080.17 EMG46696.1 - 1.8 7.3 4.3 1.9 7.2 4.3 1.2 1 0 0 1 1 1 0 Presenilin Ras PF00071.22 EMG46697.1 - 1.5e-38 131.9 0.6 3.4e-38 130.8 0.6 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EMG46697.1 - 1.1e-31 109.5 0.1 2.1e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG46697.1 - 2.7e-09 36.7 2.3 1.3e-08 34.5 1.0 2.5 1 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMG46697.1 - 1.5e-07 31.0 0.1 2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMG46697.1 - 7.3e-06 26.0 0.6 0.00054 20.0 0.1 2.4 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMG46697.1 - 6.7e-05 22.5 0.4 0.00011 21.8 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EMG46697.1 - 0.0027 17.6 1.3 0.17 11.7 0.3 2.7 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EMG46697.1 - 0.018 15.5 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 EMG46697.1 - 0.034 13.3 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 IstB_IS21 PF01695.17 EMG46697.1 - 0.15 11.8 0.1 0.77 9.5 0.0 2.1 2 1 1 3 3 3 0 IstB-like ATP binding protein APG17 PF04108.12 EMG46698.1 - 3.6e-87 293.1 6.8 4.6e-87 292.7 6.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Transcrip_act PF04949.13 EMG46698.1 - 0.0072 16.2 1.6 0.016 15.1 0.2 2.3 2 0 0 2 2 2 1 Transcriptional activator Thioredoxin_8 PF13905.6 EMG46698.1 - 0.53 10.6 3.0 6.6 7.1 0.4 3.3 2 1 0 2 2 2 0 Thioredoxin-like CDC73_C PF05179.14 EMG46699.1 - 2.2e-50 170.4 0.1 4.3e-50 169.5 0.1 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal DUF2220 PF09983.9 EMG46699.1 - 0.0065 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) tRNA-synt_2b PF00587.25 EMG46700.1 - 3.1e-39 134.8 0.0 5e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EMG46700.1 - 1.1e-16 60.7 0.2 2e-16 59.9 0.2 1.4 1 0 0 1 1 1 1 Anticodon binding domain INO80_Ies4 PF08193.11 EMG46701.1 - 1.7e-10 41.3 2.1 3.5e-08 33.7 0.0 2.2 1 1 1 2 2 2 2 INO80 complex subunit Ies4 MDM31_MDM32 PF08118.11 EMG46702.1 - 5.3e-224 744.7 7.3 6.2e-224 744.5 7.3 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins PSI_PsaF PF02507.15 EMG46702.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III THUMP PF02926.17 EMG46702.1 - 0.095 12.8 0.3 0.87 9.7 0.1 2.2 2 0 0 2 2 2 0 THUMP domain Aminotran_5 PF00266.19 EMG46703.1 - 1.8e-28 99.6 0.0 2.3e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMG46703.1 - 1.5e-09 37.5 0.0 4.5e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMG46703.1 - 3.2e-07 29.2 0.0 4.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SepSecS PF05889.13 EMG46703.1 - 0.00028 19.7 0.0 0.00071 18.4 0.0 1.6 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 EMG46703.1 - 0.0003 20.2 0.0 0.00046 19.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 EMG46703.1 - 0.026 13.4 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein 2-Hacid_dh_C PF02826.19 EMG46704.1 - 2.4e-51 173.6 0.0 4e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMG46704.1 - 8.9e-13 48.1 0.0 2e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 EMG46704.1 - 7.9e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 EMG46704.1 - 0.0012 19.0 0.0 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMG46704.1 - 0.0072 16.9 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 EMG46704.1 - 0.0086 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 EMG46704.1 - 0.082 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain G-patch PF01585.23 EMG46705.1 - 4.7e-14 52.0 4.0 6.5e-14 51.5 3.0 1.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EMG46705.1 - 3e-08 33.6 0.5 6.8e-08 32.5 0.5 1.6 1 0 0 1 1 1 1 G-patch domain Barwin PF00967.17 EMG46706.1 - 0.052 13.4 1.7 0.15 11.9 1.7 1.8 1 0 0 1 1 1 0 Barwin family Phage_lysozyme PF00959.19 EMG46706.1 - 0.068 13.6 0.3 0.2 12.1 0.3 1.7 1 0 0 1 1 1 0 Phage lysozyme 2-Hacid_dh_C PF02826.19 EMG46707.1 - 6.2e-50 169.0 0.0 8.5e-50 168.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMG46707.1 - 8.6e-09 35.2 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMG46707.1 - 2.3e-06 27.8 0.1 4.3e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EMG46707.1 - 7.1e-05 22.4 0.1 0.00012 21.7 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EMG46707.1 - 0.00018 22.0 0.1 0.00057 20.4 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 EMG46707.1 - 0.01 15.9 0.1 0.029 14.5 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EMG46707.1 - 0.043 13.8 1.0 1.8 8.5 0.1 2.6 2 1 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3015 PF11220.8 EMG46707.1 - 0.078 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF2119 PF09892.9 EMG46707.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) CRCB PF02537.15 EMG46708.1 - 4.8e-31 106.9 23.2 4.1e-20 71.9 7.8 2.8 2 1 1 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) Ribosomal_S9 PF00380.19 EMG46709.1 - 1.2e-33 116.2 0.5 1.4e-33 116.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.18 EMG46710.1 - 8.5e-69 231.0 6.0 1.3e-68 230.4 6.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e Mitoc_mL59 PF18126.1 EMG46710.1 - 7.8 6.8 10.3 38 4.6 10.3 1.9 1 1 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Ribosomal_60s PF00428.19 EMG46711.1 - 3.1e-24 85.4 15.1 3.6e-24 85.1 15.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein MFS_1 PF07690.16 EMG46712.1 - 1.7e-36 125.9 6.8 1.7e-36 125.9 6.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG46712.1 - 1.8e-08 33.7 2.4 1.8e-08 33.7 2.4 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter Voldacs PF03517.13 EMG46713.1 - 5.1e-09 36.4 8.5 1e-05 25.7 0.2 3.2 1 1 2 3 3 3 2 Regulator of volume decrease after cellular swelling WGG PF10273.9 EMG46714.1 - 1.7e-24 86.3 0.3 3.5e-24 85.2 0.3 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF4746 PF15928.5 EMG46714.1 - 0.035 13.5 6.9 0.043 13.3 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 EMG46714.1 - 0.11 11.9 9.3 0.15 11.4 9.3 1.2 1 0 0 1 1 1 0 SDA1 Ribosomal_60s PF00428.19 EMG46714.1 - 0.17 12.5 6.2 0.32 11.6 6.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Radial_spoke PF04712.12 EMG46714.1 - 0.26 10.2 9.2 0.38 9.7 9.2 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein NOA36 PF06524.12 EMG46714.1 - 0.49 9.7 10.0 0.64 9.3 10.0 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EMG46714.1 - 0.94 7.7 7.1 1.1 7.5 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein E7 PF00527.18 EMG46714.1 - 3.7 7.8 10.2 8 6.7 10.2 1.6 1 0 0 1 1 1 0 E7 protein, Early protein FAM176 PF14851.6 EMG46714.1 - 6.9 6.3 10.7 13 5.5 10.7 1.5 1 1 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 EMG46714.1 - 9.1 4.2 14.9 13 3.7 14.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 EMG46715.1 - 7.4e-188 626.4 17.3 3.1e-187 624.3 17.3 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EMG46715.1 - 5.4e-30 104.4 7.1 5.4e-30 104.4 7.1 1.9 2 0 0 2 2 2 1 Dyggve-Melchior-Clausen syndrome protein DUF5125 PF17163.4 EMG46715.1 - 0.073 13.2 1.0 0.13 12.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5125) FKBP_C PF00254.28 EMG46716.1 - 3.9e-29 100.8 0.7 9.6e-29 99.6 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EMG46716.1 - 9.1e-26 90.5 2.4 9.1e-26 90.5 2.4 2.7 2 2 0 2 2 2 1 Nucleoplasmin-like domain BUD22 PF09073.10 EMG46716.1 - 0.0014 18.1 35.3 0.0023 17.4 35.3 1.3 1 0 0 1 1 1 1 BUD22 YL1 PF05764.13 EMG46716.1 - 0.01 16.0 20.7 0.01 16.0 20.7 2.6 2 1 0 2 2 2 0 YL1 nuclear protein DNA_pol_phi PF04931.13 EMG46716.1 - 2.9 5.9 59.5 0.088 10.9 26.7 2.1 2 0 0 2 2 2 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 EMG46716.1 - 4 7.9 18.2 8.4 6.8 8.0 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 SDA1 PF05285.12 EMG46716.1 - 5.5 6.3 51.7 1.9 7.8 20.8 2.1 2 0 0 2 2 2 0 SDA1 GAGA_bind PF06217.12 EMG46716.1 - 8.5 6.6 11.1 0.99 9.6 5.5 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family Ribosomal_L6e PF01159.19 EMG46717.1 - 1e-37 129.1 2.8 1.7e-37 128.4 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e C2 PF00168.30 EMG46718.1 - 2.3e-65 217.3 5.6 1.1e-19 70.6 0.0 5.7 5 0 0 5 5 5 5 C2 domain NT-C2 PF10358.9 EMG46718.1 - 0.00075 19.2 9.9 0.42 10.3 0.6 5.3 4 2 0 4 4 4 2 N-terminal C2 in EEIG1 and EHBP1 proteins Serglycin PF04360.12 EMG46718.1 - 0.076 13.0 1.0 0.18 11.7 1.0 1.6 1 0 0 1 1 1 0 Serglycin Ribosomal_S3Ae PF01015.18 EMG46719.1 - 1.1e-87 292.9 3.3 1.3e-87 292.6 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EMG46719.1 - 0.031 14.8 0.3 0.086 13.4 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 EMG46719.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region AAA PF00004.29 EMG46720.1 - 3.7e-18 66.2 0.0 1.1e-17 64.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EMG46720.1 - 3.5e-15 55.9 0.1 9.5e-15 54.5 0.1 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 EMG46720.1 - 7.7e-11 42.7 0.0 7.4e-10 39.5 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EMG46720.1 - 1.8e-05 24.8 0.2 0.00023 21.2 0.1 2.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea BAH PF01426.18 EMG46720.1 - 8.7e-05 22.4 0.1 0.00065 19.5 0.0 2.3 2 0 0 2 2 2 1 BAH domain AAA_22 PF13401.6 EMG46720.1 - 0.00023 21.4 0.0 0.00054 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMG46720.1 - 0.0045 17.3 0.4 0.021 15.1 0.2 2.3 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 EMG46720.1 - 0.038 13.2 0.1 3.1 7.0 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain HMG-CoA_red PF00368.18 EMG46721.1 - 5.3e-143 476.5 0.8 7e-143 476.1 0.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 EMG46721.1 - 1.3e-11 44.5 5.9 3.1e-11 43.3 5.9 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation HPIH PF13323.6 EMG46721.1 - 5e-10 39.5 4.4 4.4e-09 36.4 3.7 2.6 2 1 0 2 2 2 1 N-terminal domain with HPIH motif LapA_dom PF06305.11 EMG46721.1 - 1.9 8.4 4.4 1.4 8.8 0.0 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Cyt-b5 PF00173.28 EMG46723.1 - 4e-12 46.1 0.4 5.7e-12 45.6 0.4 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF684 PF05075.14 EMG46723.1 - 0.004 16.2 0.4 0.0064 15.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF684) MFS_5 PF05631.14 EMG46723.1 - 0.045 12.7 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM Cys_Met_Meta_PP PF01053.20 EMG46724.1 - 1.1e-36 126.2 0.0 1.5e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMG46724.1 - 2.1e-05 23.8 0.0 4.9e-05 22.7 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II PDE6_gamma PF04868.12 EMG46724.1 - 0.034 14.4 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit DUF1035 PF06281.12 EMG46726.1 - 0.027 14.5 1.1 0.059 13.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) Pox_A_type_inc PF04508.12 EMG46726.1 - 0.95 9.4 5.4 1.2 9.1 0.1 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Csm1_N PF18504.1 EMG46726.1 - 2.9 8.3 6.5 6.6 7.1 0.1 3.7 4 0 0 4 4 4 0 Csm1 N-terminal domain Carn_acyltransf PF00755.20 EMG46727.1 - 3.7e-212 706.1 1.1 1.6e-211 704.0 1.1 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1708 PF08101.11 EMG46728.1 - 1.5e-125 419.8 18.5 4.7e-124 414.9 13.0 3.4 2 2 0 2 2 2 1 Domain of unknown function (DUF1708) Otopetrin PF03189.13 EMG46728.1 - 0.12 11.2 0.0 0.42 9.4 0.0 1.8 2 1 0 2 2 2 0 Otopetrin SR-25 PF10500.9 EMG46728.1 - 3.4 7.2 42.9 0.3 10.7 2.6 3.8 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein bZIP_1 PF00170.21 EMG46729.1 - 6.5e-07 29.4 2.3 1.2e-06 28.5 2.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EMG46729.1 - 2.7e-05 24.2 2.4 5.9e-05 23.1 2.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EMG46729.1 - 0.033 14.7 0.7 0.033 14.7 0.7 3.1 3 0 0 3 3 3 0 bZIP Maf transcription factor CDC45 PF02724.14 EMG46729.1 - 2 6.6 19.7 0.99 7.6 17.5 1.5 1 1 0 1 1 1 0 CDC45-like protein Glyco_hydro_47 PF01532.20 EMG46730.1 - 1e-165 552.1 0.1 1.2e-165 551.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 G_glu_transpept PF01019.21 EMG46731.1 - 5.6e-140 467.5 0.0 6.8e-140 467.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Bul1_N PF04425.12 EMG46732.1 - 1e-98 331.0 6.9 2.1e-98 330.0 6.9 1.5 1 0 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 EMG46732.1 - 1.1e-19 70.9 8.0 1.1e-19 70.9 8.0 2.9 3 1 0 3 3 3 1 Bul1 C terminus Bul1_N PF04425.12 EMG46733.1 - 2.7e-121 405.5 5.6 2.7e-121 405.5 5.6 1.7 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.12 EMG46733.1 - 2.2e-19 69.9 5.2 2.2e-19 69.9 5.2 3.4 4 1 0 4 4 4 1 Bul1 C terminus Arrestin_C PF02752.22 EMG46733.1 - 0.094 13.2 1.5 0.76 10.2 0.2 3.0 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Otopetrin PF03189.13 EMG46734.1 - 1.6 7.4 4.2 2 7.1 4.2 1.2 1 0 0 1 1 1 0 Otopetrin ALMT PF11744.8 EMG46734.1 - 2.6 6.8 8.6 4.2 6.1 8.6 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 EMG46734.1 - 2.9 6.8 12.0 5.1 6.0 12.0 1.4 1 0 0 1 1 1 0 Solute carrier family 12 PQ-loop PF04193.14 EMG46735.1 - 3.6e-22 77.9 13.1 1.6e-12 47.0 0.6 2.7 2 0 0 2 2 2 2 PQ loop repeat INCENP_ARK-bind PF03941.15 EMG46736.1 - 1.9e-06 27.7 2.4 2.1e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region TPR_1 PF00515.28 EMG46737.1 - 2.6e-10 39.6 10.2 6.7e-05 22.5 1.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMG46737.1 - 5.2e-09 35.5 4.2 0.031 14.4 0.5 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG46737.1 - 1.1e-05 25.6 2.5 2.3e-05 24.5 2.3 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EMG46737.1 - 0.00048 20.4 0.2 0.39 11.0 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 EMG46737.1 - 0.0036 17.3 6.1 0.47 10.6 0.3 3.7 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EMG46737.1 - 0.0052 16.9 8.1 2.2 8.7 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Com_YlbF PF06133.11 EMG46737.1 - 0.013 16.1 4.1 0.031 14.9 4.1 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Pox_T4_N PF04491.12 EMG46737.1 - 0.15 11.9 0.2 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus Fis1_TPR_C PF14853.6 EMG46737.1 - 1.3 9.1 5.5 7.2 6.8 0.1 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat PS_Dcarbxylase PF02666.15 EMG46738.1 - 9.1e-74 247.3 0.2 1.3e-55 188.1 0.3 2.2 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase MAP65_ASE1 PF03999.12 EMG46738.1 - 2.7 6.6 9.7 4 6.0 9.7 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ANAPC1 PF12859.7 EMG46739.1 - 8.4e-12 45.8 0.2 3.2e-11 43.9 0.2 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EMG46739.1 - 0.015 15.7 3.9 1.6 9.3 0.2 4.5 4 0 0 4 4 4 0 Proteasome/cyclosome repeat DUF5020 PF16412.5 EMG46739.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) AAA_lid_8 PF17868.1 EMG46739.1 - 0.073 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA lid domain Snf7 PF03357.21 EMG46740.1 - 1.8e-41 141.6 20.7 1.8e-41 141.6 20.7 1.8 1 1 1 2 2 2 1 Snf7 Hydantoinase_B PF02538.14 EMG46740.1 - 0.092 11.1 0.2 0.13 10.6 0.2 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase DASH_Dad4 PF08650.10 EMG46740.1 - 0.2 11.7 8.5 0.91 9.5 1.0 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad4 ArAE_2_N PF10337.9 EMG46740.1 - 0.54 9.2 5.2 0.7 8.9 5.2 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Misat_Tub_SegII PF10644.9 EMG46740.1 - 0.95 9.8 4.9 0.27 11.5 1.4 1.9 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain DUF1664 PF07889.12 EMG46740.1 - 1.9 8.6 10.9 1.1 9.3 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2443 PF10398.9 EMG46740.1 - 1.9 8.6 6.1 7 6.8 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) RPW8 PF05659.11 EMG46740.1 - 3.8 7.2 10.6 9.2 5.9 6.9 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SNARE PF05739.19 EMG46741.1 - 3.5e-15 55.7 0.1 7e-14 51.6 0.2 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EMG46741.1 - 4.2e-06 26.6 11.3 9.6e-06 25.4 1.3 2.8 3 1 0 3 3 3 2 Syntaxin Syntaxin-18_N PF10496.9 EMG46741.1 - 9.1e-05 22.6 3.6 0.00043 20.5 0.6 3.1 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Syntaxin-5_N PF11416.8 EMG46741.1 - 0.00059 19.0 2.3 0.001 18.2 1.2 2.0 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain DUF16 PF01519.16 EMG46741.1 - 0.0095 16.4 2.7 0.0095 16.4 2.7 2.6 2 1 0 2 2 2 1 Protein of unknown function DUF16 FlaC_arch PF05377.11 EMG46741.1 - 0.018 15.4 5.7 0.031 14.7 0.2 3.6 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 EMG46741.1 - 0.14 12.2 0.3 0.14 12.2 0.3 3.2 3 1 1 4 4 4 0 Laminin Domain II MCPsignal PF00015.21 EMG46741.1 - 1 9.2 8.4 0.064 13.1 1.4 2.4 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 EMG46741.1 - 1.1 9.3 8.6 1.6 8.8 1.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.21 EMG46741.1 - 1.2 9.0 5.9 0.26 11.1 0.7 2.5 2 1 0 2 2 2 0 Synaptobrevin NPV_P10 PF05531.12 EMG46741.1 - 1.8 9.1 10.9 10 6.7 0.7 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 EMG46741.1 - 3 7.9 11.2 24 5.0 11.2 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EMG46741.1 - 3.7 7.0 8.3 9.8 5.6 1.1 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Fungal_trans_2 PF11951.8 EMG46742.1 - 6.5e-64 216.1 2.4 9.1e-64 215.6 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG46742.1 - 2.7e-08 33.8 13.9 5.5e-08 32.8 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UCR_UQCRX_QCR9 PF05365.12 EMG46742.1 - 0.18 11.7 1.0 0.57 10.2 0.4 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Metallophos PF00149.28 EMG46743.1 - 3.2e-13 50.7 14.4 3.4e-13 50.6 3.9 3.9 3 1 0 3 3 3 1 Calcineurin-like phosphoesterase Mob1_phocein PF03637.17 EMG46744.1 - 4.4e-68 228.6 1.3 6e-68 228.1 1.3 1.2 1 0 0 1 1 1 1 Mob1/phocein family ORC6 PF05460.13 EMG46744.1 - 0.0026 17.1 3.0 0.0026 17.1 3.0 1.3 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) Stealth_CR1 PF17101.5 EMG46744.1 - 0.26 11.1 7.0 1.1 9.0 0.9 2.3 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 TFIIF_alpha PF05793.12 EMG46744.1 - 1.4 7.5 8.2 1.8 7.1 8.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAD-oxidase_C PF02913.19 EMG46745.1 - 1e-47 162.9 0.0 1.4e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMG46745.1 - 1.2e-30 106.1 0.0 2.5e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_62 PF03664.13 EMG46745.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 62 RNA_pol PF00940.19 EMG46746.1 - 3.6e-177 589.4 3.0 3.6e-177 589.4 3.0 1.8 2 0 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EMG46746.1 - 2.7e-87 293.3 0.0 5.5e-87 292.3 0.0 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Peptidase_M1 PF01433.20 EMG46746.1 - 0.0027 17.3 1.8 0.0066 16.0 0.5 2.2 2 1 1 3 3 3 1 Peptidase family M1 domain POC1 PF10450.9 EMG46746.1 - 0.024 13.7 0.7 0.048 12.6 0.7 1.5 1 0 0 1 1 1 0 POC1 chaperone PDZ_3 PF17815.1 EMG46746.1 - 0.083 12.8 0.2 0.22 11.4 0.2 1.7 1 0 0 1 1 1 0 PDZ domain RIC1 PF07064.13 EMG46747.1 - 2.4e-31 109.0 1.6 2.4e-31 109.0 1.6 1.7 2 0 0 2 2 2 1 RIC1 Complex1_LYR PF05347.15 EMG46748.1 - 1.6e-09 37.6 0.5 2.7e-09 36.9 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EMG46748.1 - 9e-05 23.1 1.4 0.00013 22.6 1.4 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Tubulin PF00091.25 EMG46749.1 - 2.2e-69 233.6 0.1 3.8e-69 232.9 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EMG46749.1 - 2.3e-42 144.2 0.1 3.7e-42 143.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EMG46749.1 - 8e-05 22.9 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EMG46749.1 - 0.0018 17.5 0.0 0.0041 16.4 0.0 1.6 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 EMG46749.1 - 0.0024 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Metallophos PF00149.28 EMG46750.1 - 1.2e-34 120.6 0.0 2.4e-34 119.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VHS PF00790.19 EMG46751.1 - 3.6e-21 75.5 0.1 8.3e-21 74.3 0.1 1.6 1 0 0 1 1 1 1 VHS domain FYVE PF01363.21 EMG46751.1 - 1.1e-18 67.1 3.3 2e-18 66.3 3.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EMG46751.1 - 2.9e-06 26.8 9.1 0.0015 18.3 0.4 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.16 EMG46751.1 - 0.0078 16.4 1.4 0.018 15.3 1.4 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Hrs_helical PF12210.8 EMG46751.1 - 0.048 14.2 0.7 0.14 12.7 0.7 1.7 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate GAT PF03127.14 EMG46751.1 - 0.17 12.2 3.3 0.39 11.1 3.3 1.7 1 0 0 1 1 1 0 GAT domain OAD_gamma PF04277.13 EMG46751.1 - 0.2 12.3 2.5 0.41 11.3 0.0 2.8 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-RING_2 PF13639.6 EMG46751.1 - 6.5 7.2 7.9 3.4 8.1 5.4 1.8 2 0 0 2 2 2 0 Ring finger domain Orn_Arg_deC_N PF02784.16 EMG46752.1 - 4.4e-74 249.0 0.0 5.7e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EMG46752.1 - 1.2e-17 64.0 0.0 2e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Cyclin_N PF00134.23 EMG46753.1 - 3.9e-21 75.1 0.0 7.2e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain RNase_3_N PF18497.1 EMG46753.1 - 0.061 13.5 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease III N-terminal domain Rot1 PF10681.9 EMG46754.1 - 7.9e-96 319.6 0.7 9.5e-96 319.3 0.7 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal HEPN_DZIP3 PF18738.1 EMG46754.1 - 0.036 13.8 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN DUF4428 PF14471.6 EMG46756.1 - 0.013 15.4 0.1 0.039 13.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) zf-C2H2 PF00096.26 EMG46756.1 - 0.016 15.7 1.4 0.046 14.2 1.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.7 EMG46756.1 - 0.018 15.4 2.3 0.078 13.4 2.3 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EMG46756.1 - 0.051 13.3 1.1 0.1 12.4 1.1 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 EMG46756.1 - 0.052 14.4 1.1 0.15 12.9 1.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger TFB6 PF17110.5 EMG46756.1 - 0.67 9.7 4.4 2.1 8.1 4.4 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Merozoite_SPAM PF07133.11 EMG46756.1 - 8.5 6.3 19.9 0.53 10.3 13.8 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DUF3391 PF11871.8 EMG46756.1 - 9.8 6.7 14.6 18 5.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) LRR_4 PF12799.7 EMG46757.1 - 1 9.9 4.7 1.1e+02 3.4 0.3 4.3 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 EMG46758.1 - 5.7e-06 26.6 25.8 0.00097 19.5 2.3 5.8 3 2 4 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG46758.1 - 9.6e-05 22.1 14.5 0.0045 16.7 2.5 4.7 3 1 2 5 5 5 2 Leucine rich repeat LRR_9 PF14580.6 EMG46758.1 - 0.0011 18.5 2.0 0.0021 17.6 1.1 1.9 1 1 1 2 2 2 1 Leucine-rich repeat Pentapeptide_4 PF13599.6 EMG46758.1 - 0.02 15.0 2.6 0.11 12.7 0.4 2.9 2 2 0 2 2 2 0 Pentapeptide repeats (9 copies) LRR_2 PF07723.13 EMG46758.1 - 0.58 10.9 5.6 2.2 9.1 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat EF_assoc_1 PF08355.12 EMG46759.1 - 6.5e-28 96.1 0.2 1.6e-27 94.9 0.2 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 EMG46759.1 - 4.4e-27 93.9 0.0 1.3e-26 92.4 0.0 1.8 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EMG46759.1 - 3.2e-22 78.8 0.0 5.2e-11 42.4 0.0 3.4 3 0 0 3 3 3 3 Ras family Roc PF08477.13 EMG46759.1 - 2e-13 50.6 0.0 5e-05 23.5 0.0 3.7 3 1 0 3 3 3 3 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 EMG46759.1 - 9.1e-08 31.1 5.4 0.0011 18.4 0.3 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EMG46759.1 - 1.9e-07 31.4 0.5 0.0013 19.2 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.23 EMG46759.1 - 4.8e-07 29.9 0.7 0.082 13.0 0.4 3.9 2 2 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 EMG46759.1 - 7.3e-06 26.1 1.5 0.0012 18.9 0.1 2.8 2 1 0 2 2 2 1 Dynamin family EF-hand_6 PF13405.6 EMG46759.1 - 1.4e-05 24.6 5.7 0.064 13.2 1.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EMG46759.1 - 1.6e-05 24.1 4.0 0.032 13.7 2.3 2.8 2 0 0 2 2 2 2 EF hand GTP_EFTU PF00009.27 EMG46759.1 - 4e-05 23.3 0.8 0.6 9.6 1.4 3.4 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Arf PF00025.21 EMG46759.1 - 5.4e-05 22.7 0.0 0.0044 16.5 0.0 2.8 3 0 0 3 3 2 1 ADP-ribosylation factor family AAA_18 PF13238.6 EMG46759.1 - 0.0056 17.2 0.1 0.2 12.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMG46759.1 - 0.012 16.0 0.0 6.5 7.1 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain SelP_N PF04592.14 EMG46759.1 - 0.013 14.9 10.7 0.025 14.0 10.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Septin PF00735.18 EMG46759.1 - 0.018 14.3 1.1 0.44 9.8 0.8 2.7 2 1 0 2 2 2 0 Septin ABC_tran PF00005.27 EMG46759.1 - 0.02 15.4 0.0 0.71 10.4 0.1 2.4 2 0 0 2 2 2 0 ABC transporter EF-hand_8 PF13833.6 EMG46759.1 - 0.031 14.1 3.0 3.1 7.7 0.6 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_4 PF12763.7 EMG46759.1 - 0.032 14.2 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand AAA_24 PF13479.6 EMG46759.1 - 0.045 13.5 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EMG46759.1 - 0.045 13.3 0.1 14 5.2 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B Cid2 PF09774.9 EMG46759.1 - 0.045 14.2 0.3 0.085 13.3 0.3 1.4 1 0 0 1 1 1 0 Caffeine-induced death protein 2 SRPRB PF09439.10 EMG46759.1 - 0.061 12.7 0.0 0.83 9.1 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF812 PF05667.11 EMG46759.1 - 0.065 12.1 3.0 0.059 12.3 1.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF812) RsgA_GTPase PF03193.16 EMG46759.1 - 0.11 12.4 0.3 1.3 8.9 0.1 2.9 2 1 0 3 3 3 0 RsgA GTPase TniB PF05621.11 EMG46759.1 - 0.11 11.9 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 EMG46759.1 - 0.14 12.3 0.0 14 5.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMG46759.1 - 0.16 12.3 1.3 3.4 8.1 0.5 2.9 2 1 0 2 2 2 0 RNA helicase Zip PF02535.22 EMG46759.1 - 0.98 8.6 3.3 1.6 7.8 3.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FAM76 PF16046.5 EMG46759.1 - 1.5 8.1 7.5 2.6 7.3 7.5 1.2 1 0 0 1 1 1 0 FAM76 protein Bul1_N PF04425.12 EMG46760.1 - 7e-91 305.2 6.8 3.3e-90 303.0 6.8 1.8 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 EMG46760.1 - 3.5e-18 66.0 17.8 5.4e-10 39.1 0.1 3.3 4 0 0 4 4 4 2 Bul1 C terminus ETC_C1_NDUFA4 PF04800.12 EMG46761.1 - 4.3e-32 110.2 1.4 5.7e-32 109.8 1.4 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region SWIB PF02201.18 EMG46762.1 - 5e-29 100.0 2.0 9.5e-29 99.1 0.2 2.3 2 1 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 EMG46762.1 - 6.1e-14 51.7 0.1 1.7e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 DEK C terminal domain CheR_N PF03705.15 EMG46762.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain NifW PF03206.14 EMG46762.1 - 0.072 13.6 0.6 0.54 10.8 0.3 2.3 2 0 0 2 2 2 0 Nitrogen fixation protein NifW ATP11 PF06644.11 EMG46762.1 - 0.095 12.5 4.8 0.15 11.9 4.8 1.3 1 0 0 1 1 1 0 ATP11 protein Lipase_GDSL_2 PF13472.6 EMG46763.1 - 5.1e-25 88.9 0.0 1e-24 87.9 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMG46763.1 - 7.1e-17 62.0 0.0 2.7e-16 60.2 0.0 1.9 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase RRS1 PF04939.12 EMG46764.1 - 6.2e-61 205.0 6.6 7.3e-61 204.8 6.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Sugar_tr PF00083.24 EMG46765.1 - 1.1e-77 261.9 22.6 1.2e-77 261.7 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG46765.1 - 2e-21 76.4 23.5 1.3e-19 70.4 6.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMG46765.1 - 9.2e-07 27.7 0.2 9.2e-07 27.7 0.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BBP1_C PF15272.6 EMG46766.1 - 0.00044 20.1 23.7 0.00087 19.2 23.7 1.5 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal DUF5040 PF16443.5 EMG46766.1 - 0.059 12.8 0.5 5.7 6.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5040) ERG2_Sigma1R PF04622.12 EMG46767.1 - 3.1e-90 301.1 0.4 3.7e-90 300.9 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DDE_1 PF03184.19 EMG46770.1 - 1.7e-14 53.9 0.0 6.8e-14 51.9 0.0 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 EMG46770.1 - 0.062 13.1 0.0 0.21 11.3 0.0 2.1 2 1 0 2 2 2 0 DDE superfamily endonuclease TSC22 PF01166.18 EMG46770.1 - 0.2 12.0 2.8 0.55 10.6 2.8 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.21 EMG46770.1 - 0.97 9.6 3.7 2.6 8.2 3.7 1.6 1 0 0 1 1 1 0 bZIP transcription factor PCI PF01399.27 EMG46771.1 - 1.4e-06 28.7 8.6 1.4e-06 28.7 8.6 2.8 2 1 0 2 2 2 1 PCI domain aGPT-Pplase1 PF18723.1 EMG46771.1 - 0.034 13.6 0.7 0.034 13.6 0.7 1.9 2 1 0 2 2 2 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 DUF3234 PF11572.8 EMG46771.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3234) ORC6 PF05460.13 EMG46772.1 - 1.1e-91 307.8 2.0 1.3e-91 307.5 2.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) MatE PF01554.18 EMG46773.1 - 1.1e-53 181.2 30.0 4.3e-34 117.5 8.3 2.4 2 0 0 2 2 2 2 MatE Mito_fiss_reg PF05308.11 EMG46773.1 - 0.98 9.5 3.2 1.4 8.9 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Whi5 PF08528.11 EMG46774.1 - 0.044 13.4 5.1 0.12 12.0 5.1 1.8 1 0 0 1 1 1 0 Whi5 like Autophagy_N PF03986.13 EMG46775.1 - 4.8e-47 159.3 0.4 4.8e-47 159.3 0.4 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EMG46775.1 - 1.3e-15 57.7 0.0 2.5e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EMG46775.1 - 1.1e-14 53.6 0.9 1.1e-14 53.6 0.9 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein C-terminal DUF4140 PF13600.6 EMG46775.1 - 0.69 10.4 2.8 0.5 10.8 0.3 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) LCAT PF02450.15 EMG46776.1 - 3.9e-116 388.4 0.1 5.5e-116 387.9 0.1 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 EMG46776.1 - 0.046 12.8 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 EMG46776.1 - 0.053 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Zip PF02535.22 EMG46776.1 - 7.5 5.7 6.6 13 4.9 6.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PDZ_1 PF12812.7 EMG46777.1 - 2e-49 165.5 0.1 2.9e-33 113.7 0.0 3.2 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 EMG46777.1 - 6.8e-26 92.0 0.1 3.5e-21 76.7 0.0 2.7 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 EMG46777.1 - 2.9e-15 55.8 0.1 6.6e-09 35.5 0.1 4.6 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 EMG46777.1 - 1.4e-13 50.9 0.6 0.00032 21.0 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 EMG46777.1 - 8.5e-12 45.3 0.0 3.4e-07 30.5 0.0 3.0 3 0 0 3 3 3 2 PDZ domain PDZ_3 PF17815.1 EMG46777.1 - 1.2e-06 28.5 0.2 0.05 13.4 0.1 3.9 3 1 1 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 EMG46777.1 - 0.00027 20.8 0.2 0.099 12.6 0.1 3.6 4 0 0 4 4 4 1 Tricorn protease PDZ domain Trypsin PF00089.26 EMG46777.1 - 0.0021 17.9 0.0 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 Trypsin DUF31 PF01732.16 EMG46777.1 - 0.0038 16.8 0.1 0.0064 16.1 0.1 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 EMG46777.1 - 0.0088 15.9 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 EMG46777.1 - 0.023 13.4 1.8 0.082 11.5 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 DUF4889 PF16230.5 EMG46777.1 - 0.098 12.9 0.4 0.45 10.8 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) DUF5361 PF17318.2 EMG46778.1 - 0.0093 16.2 0.3 0.015 15.5 0.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5361) Peptidase_M16 PF00675.20 EMG46778.1 - 0.063 13.3 2.9 0.081 12.9 2.9 1.1 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) Peptidase_M6 PF05547.11 EMG46778.1 - 0.46 8.8 4.5 0.38 9.0 0.8 1.9 1 1 1 2 2 2 0 Immune inhibitor A peptidase M6 XhlA PF10779.9 EMG46778.1 - 8 6.7 10.2 2.1 8.6 4.4 2.7 1 1 2 3 3 3 0 Haemolysin XhlA N-SET PF11764.8 EMG46779.1 - 5.1e-47 160.2 0.4 5.1e-47 160.2 0.4 3.6 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EMG46779.1 - 3.1e-27 94.0 0.9 6.9e-27 92.9 0.9 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 EMG46779.1 - 1.1e-18 68.2 0.2 1.1e-18 68.2 0.2 4.1 3 1 0 3 3 3 1 SET domain Myc_N PF01056.18 EMG46779.1 - 0.0045 16.9 9.2 0.0045 16.9 9.2 2.7 2 0 0 2 2 2 1 Myc amino-terminal region Pkinase PF00069.25 EMG46780.1 - 7.8e-74 248.4 0.0 1.9e-73 247.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG46780.1 - 4.6e-37 127.7 0.0 9.4e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EMG46780.1 - 6.8e-24 83.8 0.1 8.2e-12 45.1 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EMG46780.1 - 2.5e-11 43.5 0.0 5.2e-10 39.1 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EMG46780.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMG46780.1 - 0.042 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNA_pol_L_2 PF13656.6 EMG46781.1 - 3.6e-25 87.5 0.0 5.2e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EMG46781.1 - 1e-08 34.5 0.0 1.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sin3a_C PF16879.5 EMG46782.1 - 3e-80 270.0 3.2 3e-80 270.0 3.2 3.9 4 1 0 4 4 4 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 EMG46782.1 - 6e-42 141.7 0.1 1.8e-41 140.2 0.1 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 EMG46782.1 - 8.4e-40 134.7 17.0 6.3e-18 64.6 1.7 4.5 4 0 0 4 4 4 3 Paired amphipathic helix repeat Membr_traf_MHD PF10540.9 EMG46783.1 - 4.7e-39 133.9 1.8 1.9e-38 131.9 1.8 2.2 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EMG46783.1 - 4.7e-12 46.1 0.0 1.6e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 EMG46783.1 - 6.1e-05 21.8 2.1 6.1e-05 21.8 2.1 2.3 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) DUF4946 PF16304.5 EMG46783.1 - 0.092 12.4 0.1 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4946) Syntaxin-18_N PF10496.9 EMG46783.1 - 0.45 10.8 5.3 2.5 8.4 0.5 4.0 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Ion_trans PF00520.31 EMG46784.1 - 8.1e-125 415.0 117.8 1.8e-36 125.6 21.9 5.5 5 0 0 5 5 5 5 Ion transport protein GPHH PF16905.5 EMG46784.1 - 0.0027 17.4 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated CwfJ_C_2 PF04676.14 EMG46784.1 - 0.051 14.5 1.0 23 6.0 0.0 3.3 3 0 0 3 3 3 0 Protein similar to CwfJ C-terminus 2 Herpes_UL92 PF03048.14 EMG46784.1 - 0.93 9.2 4.8 18 5.0 0.1 2.6 2 0 0 2 2 2 0 UL92 family MRP-S33 PF08293.11 EMG46785.1 - 8.9e-27 93.2 0.5 1e-26 93.0 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Cnl2_NKP2 PF09447.10 EMG46785.1 - 0.11 12.7 0.1 0.56 10.4 0.1 1.9 2 0 0 2 2 2 0 Cnl2/NKP2 family protein MIS13 PF08202.11 EMG46787.1 - 1.8e-44 152.2 7.4 1.8e-44 152.2 7.4 2.2 2 1 0 2 2 2 1 Mis12-Mtw1 protein family MBF1 PF08523.10 EMG46788.1 - 4.9e-25 87.8 1.8 4.9e-25 87.8 1.8 1.9 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EMG46788.1 - 1.8e-13 50.3 0.3 4.4e-13 49.1 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 EMG46788.1 - 3.4e-06 27.0 0.2 5.5e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EMG46788.1 - 7.5e-06 26.2 0.0 2.7e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain TRAP-gamma PF07074.12 EMG46788.1 - 0.18 11.3 1.0 0.25 10.9 1.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Steroid_dh PF02544.16 EMG46789.1 - 2.2e-35 121.9 9.1 2.2e-35 121.9 9.1 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Methyltransf_25 PF13649.6 EMG46790.1 - 2e-11 44.4 0.0 9.5e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EMG46790.1 - 7.4e-11 42.0 0.0 9.8e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EMG46790.1 - 2.1e-09 37.3 0.2 2.7e-08 33.7 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG46790.1 - 8.5e-09 36.0 0.0 4.8e-08 33.6 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMG46790.1 - 2.1e-06 27.7 0.0 3.6e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EMG46790.1 - 7.3e-05 21.8 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 EMG46790.1 - 0.00026 20.9 0.0 0.00045 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMG46790.1 - 0.00054 19.3 0.0 0.0008 18.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EMG46790.1 - 0.00058 19.4 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EMG46790.1 - 0.0017 19.0 0.0 0.0045 17.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EMG46790.1 - 0.0064 16.6 0.0 0.014 15.6 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase TehB PF03848.14 EMG46790.1 - 0.041 13.3 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 EMG46790.1 - 0.047 13.7 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 EMG46790.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase zf-ZPR1 PF03367.13 EMG46791.1 - 1.7e-119 395.2 2.5 7.4e-59 198.2 0.1 2.5 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 EMG46791.1 - 0.016 15.2 4.2 2.1 8.4 0.9 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 EMG46791.1 - 0.85 9.6 4.6 2.2 8.3 0.7 2.5 2 1 0 2 2 2 0 zinc-ribbons DZR PF12773.7 EMG46791.1 - 2.1 8.4 11.8 1.2 9.3 1.7 3.2 2 1 1 3 3 3 0 Double zinc ribbon Cytochrom_C_2 PF01322.20 EMG46791.1 - 9.7 7.1 11.6 4.3 8.2 0.8 3.4 5 0 0 5 5 5 0 Cytochrome C' WD40 PF00400.32 EMG46792.1 - 4.2e-40 135.0 29.6 6.8e-07 29.9 0.0 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 EMG46792.1 - 9.9e-14 50.9 13.8 0.0012 17.6 0.4 6.3 2 1 4 6 6 6 6 Nucleoporin Nup120/160 F-box-like PF12937.7 EMG46792.1 - 1.1e-13 50.8 2.7 2.4e-13 49.8 2.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMG46792.1 - 5.4e-12 45.3 2.3 1.3e-11 44.0 2.3 1.7 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 EMG46792.1 - 4.8e-08 32.7 3.4 7.1e-06 25.6 0.8 2.3 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 EMG46792.1 - 2.7e-07 30.8 4.4 0.28 11.5 0.0 5.1 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EMG46792.1 - 3.8e-07 30.1 0.1 0.0098 15.9 0.0 4.3 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 EMG46792.1 - 0.028 14.3 1.0 1.9 8.3 0.0 3.1 2 2 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A F-box_4 PF15966.5 EMG46792.1 - 0.039 13.8 0.1 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 F-box CBM_21 PF03370.13 EMG46794.1 - 3.4e-36 123.9 1.7 3.4e-36 123.9 1.7 2.1 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EMG46794.1 - 0.00029 21.3 6.3 0.048 14.3 6.3 3.1 1 1 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) PBP1_TM PF14812.6 EMG46794.1 - 2.3 8.6 18.9 0.12 12.7 3.6 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FMO-like PF00743.19 EMG46795.1 - 1.1e-40 139.7 0.3 9.5e-21 73.8 0.3 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMG46795.1 - 1.5e-19 70.4 1.1 3e-15 56.3 0.3 3.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMG46795.1 - 1.3e-11 44.2 0.0 5.5e-10 38.9 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMG46795.1 - 2.4e-11 43.9 0.0 2.9e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EMG46795.1 - 5.6e-10 39.3 0.0 0.0026 17.4 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EMG46795.1 - 1.1e-07 31.0 0.0 5.2e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 HI0933-like protein K_oxygenase PF13434.6 EMG46795.1 - 1.4e-06 27.7 0.0 0.00015 21.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EMG46795.1 - 2e-06 28.0 0.0 6.2e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Glu_dehyd_C PF16912.5 EMG46795.1 - 0.00012 21.6 0.0 0.083 12.4 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 EMG46795.1 - 0.00028 21.4 1.0 0.91 10.1 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMG46795.1 - 0.028 13.7 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 EMG46795.1 - 0.042 14.3 0.1 0.54 10.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 EMG46795.1 - 0.077 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HORMA PF02301.18 EMG46796.1 - 3.3e-47 160.8 0.2 3.3e-47 160.8 0.2 1.7 2 0 0 2 2 2 1 HORMA domain DZR PF12773.7 EMG46796.1 - 0.037 14.0 0.5 0.074 13.1 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EMG46796.1 - 0.11 11.9 0.2 0.27 10.7 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Zn_clus PF00172.18 EMG46797.1 - 5.4e-07 29.6 8.0 5.4e-07 29.6 8.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KH_6 PF15985.5 EMG46798.1 - 1e-16 61.0 0.2 1.9e-16 60.2 0.2 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 EMG46798.1 - 3.7e-16 58.8 0.6 5.8e-16 58.2 0.6 1.3 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain LCM PF04072.14 EMG46799.1 - 1.6e-21 77.1 0.0 2.7e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 EMG46799.1 - 1e-20 73.5 3.4 3.8e-12 46.0 0.0 5.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EMG46799.1 - 4.5e-19 68.3 0.4 2.2e-07 31.0 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EMG46799.1 - 6.9e-15 54.7 1.6 0.00053 19.9 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 EMG46799.1 - 1.9e-11 43.8 3.0 0.0017 18.6 0.0 5.3 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EMG46799.1 - 1.8e-08 34.0 0.3 0.0039 17.1 0.0 4.4 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EMG46799.1 - 1.9e-06 27.3 1.5 0.034 13.7 0.0 4.7 5 0 0 5 5 5 1 Kelch motif BAR_3 PF16746.5 EMG46800.1 - 9.6e-22 77.9 1.3 9.6e-22 77.9 1.3 1.9 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 EMG46800.1 - 2.7e-09 37.5 0.6 2.7e-09 37.5 0.6 2.2 3 0 0 3 3 3 1 PH domain VASt PF16016.5 EMG46800.1 - 1.4e-07 32.1 0.0 3.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DUF1204 PF06721.11 EMG46800.1 - 0.014 14.9 1.0 0.027 13.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) XkdW PF09636.10 EMG46800.1 - 0.31 11.1 7.4 1.2 9.2 0.1 4.1 3 1 2 5 5 5 0 XkdW protein Fungal_trans PF04082.18 EMG46801.1 - 1.2e-19 70.4 1.6 2.5e-19 69.4 0.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG46801.1 - 1.4e-09 37.9 14.7 2.5e-09 37.1 14.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rpn3_C PF08375.11 EMG46802.1 - 4.4e-26 91.1 0.5 1.6e-25 89.3 0.5 2.0 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EMG46802.1 - 2.8e-22 79.2 2.3 4.7e-22 78.5 0.3 2.5 3 1 0 3 3 3 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 EMG46802.1 - 0.064 13.2 0.3 0.47 10.4 0.0 2.3 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family DUF3237 PF11578.8 EMG46803.1 - 4.1e-24 85.1 0.0 4.6e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Ras PF00071.22 EMG46804.1 - 1.2e-64 216.8 0.2 1.5e-64 216.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG46804.1 - 1.1e-36 125.7 0.1 1.8e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG46804.1 - 6.2e-17 61.6 0.1 7.9e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMG46804.1 - 2.5e-06 27.0 0.1 2.8e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EMG46804.1 - 7.7e-05 22.7 0.3 0.16 11.9 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMG46804.1 - 0.00014 21.9 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMG46804.1 - 0.0002 21.0 0.2 0.00066 19.3 0.1 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EMG46804.1 - 0.00065 19.2 0.0 0.00098 18.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 EMG46804.1 - 0.003 18.0 0.0 0.056 13.9 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMG46804.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EMG46804.1 - 0.033 13.9 0.0 1.4 8.7 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EMG46804.1 - 0.046 14.0 0.0 0.14 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMG46804.1 - 0.048 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain CENP-M PF11111.8 EMG46804.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) TniB PF05621.11 EMG46804.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EMG46804.1 - 0.12 11.9 0.1 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 EMG46804.1 - 0.14 12.1 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EMG46804.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TRAM_LAG1_CLN8 PF03798.16 EMG46805.1 - 9.4e-36 123.4 22.3 9.4e-36 123.4 22.3 1.8 2 0 0 2 2 2 1 TLC domain ArfGap PF01412.18 EMG46806.1 - 1.4e-26 92.9 6.5 1.5e-26 92.8 4.2 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.29 EMG46806.1 - 3e-13 50.2 0.1 2.7e-12 47.1 0.1 2.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EMG46806.1 - 1.9e-06 28.2 0.4 1.3e-05 25.5 0.4 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain BAR_3 PF16746.5 EMG46806.1 - 0.00071 19.4 6.4 0.011 15.4 6.4 2.6 1 1 0 1 1 1 1 BAR domain of APPL family PH_6 PF15406.6 EMG46806.1 - 0.0062 16.8 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase PF00069.25 EMG46807.1 - 4.9e-66 222.8 0.0 7.6e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG46807.1 - 1.2e-47 162.4 0.0 2.2e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG46807.1 - 3.2e-05 22.9 0.1 0.00044 19.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EMG46807.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMG46807.1 - 0.056 12.8 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EMG46807.1 - 0.16 11.9 0.0 3.6 7.4 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family TEA PF01285.18 EMG46808.1 - 5.3e-08 32.8 0.2 2.4e-07 30.7 0.2 2.3 1 0 0 1 1 1 1 TEA/ATTS domain Nop25 PF09805.9 EMG46808.1 - 1.2 9.6 5.8 4.2 7.8 5.8 1.9 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) MRP-L27 PF09809.9 EMG46809.1 - 1.5e-29 102.1 0.3 3.4e-29 100.9 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 CBFD_NFYB_HMF PF00808.23 EMG46809.1 - 1.9e-08 34.5 0.0 3.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMG46809.1 - 0.00015 22.2 0.5 0.00044 20.6 0.5 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Lin-8 PF03353.15 EMG46809.1 - 0.16 11.5 7.5 0.28 10.7 7.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF5377 PF17347.2 EMG46810.1 - 0.049 14.0 0.9 7.5 7.0 0.1 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5377) Ribosomal_S8 PF00410.19 EMG46811.1 - 8.8e-21 74.2 0.1 1.3e-20 73.6 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Peptidase_S24 PF00717.23 EMG46812.1 - 1.9e-07 31.0 0.0 7e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 EMG46812.1 - 8.7e-05 22.3 0.0 0.00032 20.5 0.0 1.9 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Ribophorin_II PF05817.14 EMG46813.1 - 7.9e-15 54.4 1.7 8.7e-15 54.3 1.7 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Med17 PF10156.9 EMG46814.1 - 1e-121 406.9 16.8 1.8e-121 406.1 16.8 1.3 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Glyco_hydro81C PF17652.1 EMG46815.1 - 3.5e-142 473.8 9.5 5e-142 473.3 9.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EMG46815.1 - 9e-96 320.8 1.0 9e-96 320.8 1.0 3.0 2 1 1 4 4 4 1 Glycosyl hydrolase family 81 N-terminal domain DAO PF01266.24 EMG46816.1 - 6.9e-24 85.1 0.0 9.9e-24 84.6 0.0 1.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMG46816.1 - 0.00015 21.1 0.1 0.0018 17.6 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMG46816.1 - 0.028 13.7 1.1 0.077 12.2 0.0 2.2 3 0 0 3 3 3 0 Thi4 family MFS_1 PF07690.16 EMG46818.1 - 1.9e-33 115.9 22.9 3.1e-33 115.2 22.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG46818.1 - 6.9e-11 41.7 5.1 6.9e-11 41.7 5.1 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EMG46818.1 - 0.0056 15.2 4.1 0.0079 14.7 0.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4768 PF15989.5 EMG46818.1 - 0.059 13.3 0.7 0.3 11.0 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4768) DUF3267 PF11667.8 EMG46818.1 - 0.45 10.8 12.0 3.9 7.8 0.0 3.9 3 1 1 4 4 4 0 Putative zincin peptidase GRASP55_65 PF04495.14 EMG46819.1 - 2.6e-45 154.1 0.0 4e-41 140.5 0.0 2.3 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PRANC PF09372.10 EMG46820.1 - 0.3 11.5 3.2 0.87 10.0 1.7 2.6 2 0 0 2 2 2 0 PRANC domain F-box PF00646.33 EMG46820.1 - 0.57 10.1 4.2 4.2 7.4 0.3 4.1 4 0 0 4 4 4 0 F-box domain F-box-like PF12937.7 EMG46820.1 - 0.58 10.1 2.0 1.1 9.2 0.5 2.3 2 0 0 2 2 2 0 F-box-like FNIP PF05725.12 EMG46820.1 - 0.9 9.8 28.0 11 6.3 0.1 8.8 9 2 0 9 9 9 0 FNIP Repeat LRR_8 PF13855.6 EMG46820.1 - 3.7 7.4 9.4 6.2 6.7 0.9 5.5 6 1 1 7 7 7 0 Leucine rich repeat MFS_1 PF07690.16 EMG46821.1 - 2.4e-26 92.5 19.1 2.2e-17 63.0 5.5 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG46821.1 - 1.9e-09 36.9 13.5 3.7e-09 35.9 2.2 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter PsbW PF07123.12 EMG46821.1 - 0.031 14.3 0.2 0.031 14.3 0.2 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) DUF2235 PF09994.9 EMG46821.1 - 0.11 11.8 0.1 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) KilA-N PF04383.13 EMG46822.1 - 8.7e-09 35.2 0.1 9.2e-08 31.9 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain DUF3258 PF11646.8 EMG46822.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function DUF3258 Aldedh PF00171.22 EMG46823.1 - 1.4e-160 534.8 0.0 1.6e-160 534.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EMG46823.1 - 6.3e-05 22.5 0.0 0.00084 18.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Flagellin_N PF00669.20 EMG46824.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Ank PF00023.30 EMG46825.1 - 2.6e-15 56.1 1.6 1.9e-06 28.0 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EMG46825.1 - 2.5e-14 53.6 1.4 1.5e-05 25.5 1.2 3.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMG46825.1 - 3.7e-14 51.4 0.9 6e-05 23.1 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EMG46825.1 - 6.3e-12 45.5 1.0 0.00021 21.5 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMG46825.1 - 1.9e-11 44.2 2.1 0.00016 22.2 0.1 4.4 3 2 2 5 5 5 3 Ankyrin repeats (many copies) DUF4407 PF14362.6 EMG46825.1 - 0.24 10.7 3.1 0.52 9.6 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 EMG46825.1 - 0.29 10.4 6.2 0.96 8.7 6.2 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Cyclin_C_2 PF16899.5 EMG46826.1 - 7.3e-27 93.8 0.2 6.1e-25 87.6 0.0 2.5 2 1 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EMG46826.1 - 2.7e-10 40.1 0.5 5.3e-10 39.1 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain PALP PF00291.25 EMG46827.1 - 9.6e-55 186.1 0.0 1.2e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EMG46827.1 - 6.7e-14 52.1 0.1 1.3e-08 35.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain PBP-Tp47_a PF14889.6 EMG46827.1 - 0.037 13.7 0.0 0.22 11.2 0.0 2.2 3 1 0 3 3 3 0 Penicillin-binding protein Tp47 domain a TFIIS_M PF07500.14 EMG46828.1 - 2.6e-29 102.0 3.7 2.6e-29 102.0 3.7 2.3 2 1 2 4 4 4 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EMG46828.1 - 2.7e-18 65.5 7.5 4.6e-18 64.8 7.5 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EMG46828.1 - 1e-10 41.4 1.5 1e-10 41.4 1.5 2.4 2 1 0 2 2 2 1 TFIIS helical bundle-like domain IQCJ-SCHIP1 PF15157.6 EMG46828.1 - 0.047 13.5 0.2 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Baculo_LEF5_C PF11792.8 EMG46828.1 - 0.06 13.0 1.4 0.13 12.0 1.4 1.6 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Elf1 PF05129.13 EMG46828.1 - 0.066 13.3 2.9 0.19 11.8 2.9 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like LINES_C PF14695.6 EMG46828.1 - 0.42 10.1 1.5 0.65 9.5 0.2 2.1 2 0 0 2 2 2 0 Lines C-terminus DHHA1 PF02272.19 EMG46828.1 - 1 9.7 3.3 1.3 9.4 0.8 2.1 2 0 0 2 2 2 0 DHHA1 domain CSTF2_hinge PF14327.6 EMG46829.1 - 1.1e-17 64.3 4.7 1.6e-17 63.7 4.7 1.3 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EMG46829.1 - 1.8e-15 56.5 0.0 5.5e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCAI PF12070.8 EMG46829.1 - 0.00035 19.6 2.8 0.00046 19.2 2.8 1.1 1 0 0 1 1 1 1 Protein SCAI RRM_occluded PF16842.5 EMG46829.1 - 0.0044 16.9 0.3 0.12 12.2 0.0 2.9 3 1 1 4 4 4 1 Occluded RNA-recognition motif CSTF_C PF14304.6 EMG46829.1 - 0.041 13.5 0.2 0.087 12.4 0.2 1.5 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Peptidase_M24_C PF16188.5 EMG46829.1 - 0.12 12.5 0.3 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 Rho_GDI PF02115.17 EMG46830.1 - 2.4e-12 47.0 0.1 3e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Beach PF02138.18 EMG46830.1 - 0.042 13.2 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 Beige/BEACH domain UQ_con PF00179.26 EMG46831.1 - 7.8e-38 129.3 0.0 9.8e-38 129.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FliD_C PF07195.12 EMG46831.1 - 0.081 12.3 1.3 0.11 11.9 1.3 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus GP67 PF17634.2 EMG46831.1 - 0.22 11.9 10.6 0.37 11.2 10.6 1.3 1 0 0 1 1 1 0 Gene product 67 Astro_capsid_p PF12226.8 EMG46831.1 - 4.8 6.2 9.1 6.5 5.8 9.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein AMPK1_CBM PF16561.5 EMG46833.1 - 4e-11 43.0 0.9 9.6e-11 41.8 0.9 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Nop16 PF09420.10 EMG46833.1 - 7.6 6.5 7.7 14 5.6 7.5 1.7 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 ABC_tran PF00005.27 EMG46834.1 - 3e-52 176.8 0.1 7.4e-26 91.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EMG46834.1 - 4.9e-36 124.1 47.9 5.5e-21 75.0 10.8 2.5 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.6 EMG46834.1 - 2.5e-13 50.5 20.7 7.3e-06 26.0 0.2 5.2 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EMG46834.1 - 3.7e-12 46.5 3.5 2.1e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 EMG46834.1 - 5e-11 42.5 0.7 1.9e-06 27.5 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMG46834.1 - 1.5e-09 38.5 0.5 0.00027 21.4 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 EMG46834.1 - 2.9e-09 36.4 1.8 0.00067 18.8 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 EMG46834.1 - 5.4e-09 36.5 1.6 0.0038 17.5 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMG46834.1 - 1.2e-07 31.3 2.0 0.0065 16.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 EMG46834.1 - 1.3e-07 32.2 0.5 0.0097 16.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 EMG46834.1 - 2.9e-07 30.9 0.1 0.019 15.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EMG46834.1 - 2.3e-06 28.0 0.2 0.036 14.5 0.0 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EMG46834.1 - 4e-06 26.9 0.1 0.14 12.2 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 EMG46834.1 - 6e-06 26.0 0.6 0.036 13.7 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EMG46834.1 - 6.4e-06 26.2 0.4 0.18 11.7 0.0 2.9 3 0 0 3 3 2 2 NACHT domain ATPase_2 PF01637.18 EMG46834.1 - 7.6e-06 26.0 2.4 0.0048 16.8 0.0 3.1 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EMG46834.1 - 9e-06 25.5 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EMG46834.1 - 9.7e-06 25.6 0.3 0.3 11.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EMG46834.1 - 1.9e-05 24.8 0.3 0.37 11.1 0.0 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EMG46834.1 - 2.5e-05 24.1 1.2 0.3 10.8 0.1 3.2 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.15 EMG46834.1 - 3e-05 24.0 0.1 0.23 11.3 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_14 PF13173.6 EMG46834.1 - 3.1e-05 24.0 0.3 0.21 11.6 0.0 3.5 3 0 0 3 3 2 2 AAA domain ATP_bind_1 PF03029.17 EMG46834.1 - 4.6e-05 23.3 0.1 0.17 11.7 0.1 2.6 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 EMG46834.1 - 6.5e-05 23.3 0.1 0.3 11.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EMG46834.1 - 7.4e-05 23.1 0.1 0.1 13.0 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 EMG46834.1 - 9.4e-05 23.0 1.9 0.0048 17.4 0.1 4.0 3 1 1 4 4 3 2 AAA domain Pox_A32 PF04665.12 EMG46834.1 - 9.7e-05 21.9 0.2 0.065 12.7 0.1 2.5 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_7 PF12775.7 EMG46834.1 - 0.0002 21.0 1.5 0.4 10.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Septin PF00735.18 EMG46834.1 - 0.00021 20.7 0.2 0.13 11.5 0.1 2.7 2 0 0 2 2 2 1 Septin AAA_33 PF13671.6 EMG46834.1 - 0.00023 21.4 0.1 0.18 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EMG46834.1 - 0.00036 20.0 0.9 0.042 13.2 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family dNK PF01712.19 EMG46834.1 - 0.00037 20.4 0.2 1.1 9.0 0.1 2.5 2 0 0 2 2 2 2 Deoxynucleoside kinase MobB PF03205.14 EMG46834.1 - 0.00054 19.9 0.2 0.65 9.9 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 EMG46834.1 - 0.00069 19.4 0.2 4.7 6.9 0.0 3.6 4 0 0 4 4 3 0 IstB-like ATP binding protein SRPRB PF09439.10 EMG46834.1 - 0.00076 19.0 0.4 0.97 8.8 0.0 2.6 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit ATP-synt_ab PF00006.25 EMG46834.1 - 0.00088 19.0 0.0 0.047 13.3 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 EMG46834.1 - 0.001 19.5 1.0 0.9 10.0 0.1 3.2 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 EMG46834.1 - 0.0011 18.2 0.0 0.34 10.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 EMG46834.1 - 0.0012 18.5 0.0 0.49 9.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 EMG46834.1 - 0.0012 18.7 0.4 3.1 7.7 0.0 3.1 3 0 0 3 3 3 0 NTPase Roc PF08477.13 EMG46834.1 - 0.0013 18.9 0.0 1 9.6 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EMG46834.1 - 0.0015 17.9 0.1 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin PduV-EutP PF10662.9 EMG46834.1 - 0.0019 17.9 1.2 2.3 8.0 0.1 2.8 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation PRK PF00485.18 EMG46834.1 - 0.0029 17.4 0.1 0.6 9.8 0.1 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 EMG46834.1 - 0.0036 17.0 0.2 3 7.4 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 EMG46834.1 - 0.0053 16.8 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 EMG46834.1 - 0.0053 16.0 0.4 1.4 8.0 0.0 2.5 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.9 EMG46834.1 - 0.018 14.3 0.1 5 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AFG1_ATPase PF03969.16 EMG46834.1 - 0.02 13.8 0.0 2 7.2 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase TIP49 PF06068.13 EMG46834.1 - 0.025 13.8 1.1 0.33 10.1 0.0 2.5 3 0 0 3 3 2 0 TIP49 P-loop domain Sigma54_activat PF00158.26 EMG46834.1 - 0.026 14.2 0.2 3.2 7.4 0.0 3.0 3 0 0 3 3 2 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 EMG46834.1 - 0.041 13.1 0.0 3.9 6.6 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain Thymidylate_kin PF02223.17 EMG46834.1 - 0.052 13.2 0.0 13 5.4 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_13 PF13166.6 EMG46834.1 - 0.058 12.0 16.2 0.065 11.9 0.2 4.4 4 1 0 4 4 4 0 AAA domain ATPase PF06745.13 EMG46834.1 - 0.068 12.5 1.1 10 5.4 0.1 3.6 3 1 0 3 3 3 0 KaiC Mg_chelatase PF01078.21 EMG46834.1 - 0.077 12.4 0.4 2 7.7 0.0 3.0 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 EMG46834.1 - 0.08 12.7 0.0 6.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase PhoH PF02562.16 EMG46834.1 - 0.088 12.2 0.1 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein GTP_EFTU PF00009.27 EMG46834.1 - 0.1 12.1 0.1 3.4 7.1 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF87 PF01935.17 EMG46834.1 - 0.11 12.5 8.2 2.4 8.2 0.1 4.0 4 0 0 4 4 4 0 Helicase HerA, central domain DnaB_C PF03796.15 EMG46834.1 - 0.17 11.2 1.8 11 5.2 0.0 3.0 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain AAA_11 PF13086.6 EMG46834.1 - 0.39 10.5 4.1 1.7 8.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 EMG46834.1 - 3.1 7.8 7.5 11 6.1 0.0 3.1 3 0 0 3 3 2 0 Dynamin family UPF0160 PF03690.13 EMG46835.1 - 1.8e-132 441.8 0.0 2e-132 441.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SUI1 PF01253.22 EMG46836.1 - 5e-20 71.8 0.3 1.5e-19 70.3 0.3 1.9 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EMG46836.1 - 1.5e-15 57.6 3.7 2.2e-15 57.1 0.5 2.8 3 1 0 3 3 3 1 Pre-PUA-like domain Kin17_mid PF10357.9 EMG46836.1 - 4.3e-06 26.7 0.9 6.2e-05 22.9 0.1 2.5 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein PUA PF01472.20 EMG46836.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 PUA domain MMR_HSR1_C PF08438.10 EMG46836.1 - 0.096 13.3 0.3 5.4 7.6 0.1 2.7 2 0 0 2 2 2 0 GTPase of unknown function C-terminal UBX PF00789.20 EMG46837.1 - 1.5e-11 44.3 0.1 5.1e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.6 EMG46837.1 - 0.00055 20.1 0.1 0.0014 18.7 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like HAD_SAK_1 PF10307.9 EMG46837.1 - 0.0033 17.2 1.7 0.0063 16.4 1.7 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins TMEM208_SND2 PF05620.11 EMG46838.1 - 1.9e-53 180.7 0.0 2.3e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 CwfJ_C_1 PF04677.15 EMG46839.1 - 2.8e-25 88.6 0.0 4.6e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EMG46839.1 - 8.2e-15 55.5 0.3 1.9e-14 54.3 0.3 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 SET PF00856.28 EMG46840.1 - 5.2e-05 23.7 0.0 6.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 EMG46840.1 - 0.0064 16.6 0.0 0.02 15.0 0.0 1.8 1 1 0 1 1 1 1 MYND finger YHS PF04945.13 EMG46840.1 - 0.067 13.3 5.8 0.17 12.0 3.0 2.6 3 0 0 3 3 3 0 YHS domain Bac_rhodopsin PF01036.18 EMG46841.1 - 2.7e-74 249.5 20.2 3.2e-74 249.3 20.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein ABC2_membrane_2 PF12679.7 EMG46841.1 - 0.44 9.8 10.2 0.19 11.0 5.8 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein YwcE PF17368.2 EMG46841.1 - 5.4 7.8 12.2 0.76 10.5 0.4 2.9 3 0 0 3 3 3 0 Spore morphogenesis and germination YwcE UCH PF00443.29 EMG46842.1 - 1.4e-27 96.8 7.7 1.7e-25 90.0 4.5 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase HEPN-like_int PF18867.1 EMG46842.1 - 0.029 14.2 6.4 0.036 13.9 0.1 3.4 4 0 0 4 4 4 0 HEPN-like integron domain SDA1 PF05285.12 EMG46842.1 - 0.22 10.9 16.5 0.43 9.9 16.5 1.5 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 EMG46842.1 - 2.6 7.1 23.0 6.1 5.9 23.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 EMG46842.1 - 3.3 5.7 26.2 6.2 4.8 26.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EMG46842.1 - 6.3 5.0 16.5 11 4.2 16.5 1.3 1 0 0 1 1 1 0 CDC45-like protein 5-FTHF_cyc-lig PF01812.20 EMG46843.1 - 6e-43 146.9 0.0 6.9e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Peptidase_S41_N PF11918.8 EMG46843.1 - 0.066 13.4 0.5 0.1 12.8 0.5 1.2 1 0 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Fungal_trans PF04082.18 EMG46844.1 - 1.8e-15 56.7 0.3 3.1e-15 55.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG46844.1 - 4.1e-08 33.2 7.6 9e-08 32.1 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_rhodopsin PF01036.18 EMG46845.1 - 2e-69 233.6 21.3 2.4e-69 233.3 21.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein SPX PF03105.19 EMG46847.1 - 4.4e-44 151.9 6.1 3.6e-28 99.6 1.5 2.1 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 EMG46847.1 - 4.7e-27 95.2 47.9 6.8e-27 94.6 47.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EMG46847.1 - 8.7e-21 74.4 70.1 6.4e-20 71.5 37.6 2.2 1 1 1 2 2 2 2 Citrate transporter PIG-P PF08510.12 EMG46847.1 - 0.0023 17.9 0.4 0.013 15.4 0.4 2.3 1 0 0 1 1 1 1 PIG-P PBP1_TM PF14812.6 EMG46847.1 - 0.41 11.0 4.7 1.2 9.5 4.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kinesin PF00225.23 EMG46848.1 - 6.1e-100 334.4 1.3 9.7e-100 333.7 1.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMG46848.1 - 3.5e-23 82.2 0.2 3.5e-23 82.2 0.2 3.0 2 1 0 3 3 3 1 Microtubule binding NRBF2 PF08961.10 EMG46848.1 - 0.0077 15.9 1.3 0.0077 15.9 1.3 3.4 3 1 2 5 5 5 1 Nuclear receptor-binding factor 2, autophagy regulator Csm1_N PF18504.1 EMG46848.1 - 0.088 13.2 6.0 3.1 8.2 0.6 3.1 2 0 0 2 2 2 0 Csm1 N-terminal domain IL5 PF02025.15 EMG46848.1 - 0.091 13.1 2.2 0.35 11.2 2.2 2.0 1 1 0 1 1 1 0 Interleukin 5 TSC22 PF01166.18 EMG46848.1 - 0.1 12.9 6.9 3 8.2 1.2 3.4 2 1 1 3 3 3 0 TSC-22/dip/bun family Pre-PUA PF17832.1 EMG46848.1 - 0.29 11.8 3.1 6.2 7.6 0.2 2.8 2 0 0 2 2 2 0 Pre-PUA-like domain Fzo_mitofusin PF04799.13 EMG46848.1 - 0.8 9.2 7.2 0.097 12.2 2.5 1.9 2 0 0 2 2 2 0 fzo-like conserved region YabA PF06156.13 EMG46848.1 - 0.86 10.3 16.5 2.9 8.6 6.1 3.7 3 1 0 3 3 3 0 Initiation control protein YabA TolA_bind_tri PF16331.5 EMG46848.1 - 0.9 9.7 4.8 0.26 11.4 0.8 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation JIP_LZII PF16471.5 EMG46848.1 - 1.3 9.3 7.0 3.5 7.9 2.1 3.1 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 EMG46848.1 - 2.5 7.3 9.6 2 7.6 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Sugar_tr PF00083.24 EMG46849.1 - 2e-103 346.7 31.0 2.5e-103 346.4 31.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG46849.1 - 1e-21 77.3 37.2 2.9e-21 75.8 30.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 EMG46849.1 - 0.18 12.4 2.2 0.63 10.6 2.2 1.9 1 0 0 1 1 1 0 Phage holin family 2 Pkinase PF00069.25 EMG46850.1 - 3.3e-36 125.0 4.9 2.4e-22 79.6 1.7 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EMG46850.1 - 1.1e-14 54.4 2.0 7.4e-09 35.3 0.5 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase SRAP PF02586.14 EMG46851.1 - 2.2e-47 161.4 0.7 2.6e-46 157.9 0.7 2.4 1 1 0 1 1 1 1 SOS response associated peptidase (SRAP) MRP-S28 PF10213.9 EMG46851.1 - 1.6e-36 125.6 4.9 3.7e-36 124.3 4.9 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein FAD_binding_3 PF01494.19 EMG46852.1 - 5.9e-19 68.5 1.2 3.9e-17 62.5 1.2 2.9 1 1 0 1 1 1 1 FAD binding domain PGAP1 PF07819.13 EMG46852.1 - 8.5e-06 25.7 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EMG46852.1 - 2.9e-05 23.7 0.0 9.5e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EMG46852.1 - 0.00045 20.1 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Pyr_redox_2 PF07992.14 EMG46852.1 - 0.00048 19.5 0.0 0.0019 17.5 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF915 PF06028.11 EMG46852.1 - 0.0014 18.1 0.0 0.054 12.8 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Lycopene_cycl PF05834.12 EMG46852.1 - 0.0021 17.2 0.1 0.038 13.0 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein LCAT PF02450.15 EMG46852.1 - 0.0025 17.1 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Trp_halogenase PF04820.14 EMG46852.1 - 0.0071 15.2 0.0 0.79 8.5 0.0 2.3 2 0 0 2 2 2 1 Tryptophan halogenase Abhydrolase_1 PF00561.20 EMG46852.1 - 0.025 14.2 0.0 0.058 13.0 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold NAD_binding_9 PF13454.6 EMG46852.1 - 0.031 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.10 EMG46852.1 - 0.042 12.9 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 EMG46852.1 - 0.11 11.8 0.0 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Aldedh PF00171.22 EMG46853.1 - 2e-114 382.6 0.0 2.3e-114 382.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_23 PF13489.6 EMG46854.1 - 6.2e-18 65.2 0.0 9.2e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG46854.1 - 1.6e-17 64.0 0.4 7.9e-17 61.8 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG46854.1 - 4.4e-14 52.9 0.0 1.2e-13 51.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG46854.1 - 1.7e-11 44.6 0.0 4.2e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMG46854.1 - 4.4e-08 33.1 0.1 1.9e-07 31.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EMG46854.1 - 2.1e-05 23.9 0.0 0.046 12.9 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 EMG46854.1 - 3.9e-05 23.1 0.0 6.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMG46854.1 - 0.0011 18.3 0.1 0.0024 17.2 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EMG46854.1 - 0.0064 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 EMG46854.1 - 0.0094 17.0 0.0 0.018 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EMG46854.1 - 0.089 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3298 PF11738.8 EMG46854.1 - 0.19 12.8 1.6 1.2 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) Pet100 PF09803.9 EMG46855.1 - 0.11 13.1 1.8 13 6.4 0.1 2.7 2 0 0 2 2 2 0 Pet100 GalP_UDP_transf PF01087.22 EMG46856.1 - 4.8e-69 232.5 0.1 8.4e-69 231.7 0.1 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EMG46856.1 - 1.2e-65 220.3 0.9 2.7e-65 219.2 0.8 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.8 EMG46856.1 - 0.0019 18.7 0.2 0.0042 17.6 0.2 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF4921 PF16268.5 EMG46856.1 - 0.004 16.0 0.4 0.56 9.0 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4921) HIT PF01230.23 EMG46856.1 - 0.12 13.2 0.1 0.52 11.1 0.0 2.0 2 0 0 2 2 2 0 HIT domain GDP_Man_Dehyd PF16363.5 EMG46857.1 - 6.2e-64 216.5 0.0 8e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMG46857.1 - 8.3e-51 172.8 0.0 9.8e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG46857.1 - 1.2e-13 50.8 0.0 1.5e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMG46857.1 - 4.5e-11 42.4 0.0 7.2e-10 38.5 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EMG46857.1 - 1.9e-08 33.8 0.0 2.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EMG46857.1 - 6.7e-08 32.0 0.0 2.1e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein HIGH_NTase1 PF05636.11 EMG46857.1 - 0.0053 16.0 0.3 0.0085 15.3 0.3 1.3 1 0 0 1 1 1 1 HIGH Nucleotidyl Transferase Aldose_epim PF01263.20 EMG46858.1 - 1.3e-70 238.1 1.9 2.2e-70 237.4 0.7 1.8 1 1 1 2 2 2 1 Aldose 1-epimerase GDP_Man_Dehyd PF16363.5 EMG46858.1 - 4.4e-54 184.1 0.0 6.2e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMG46858.1 - 7.6e-50 169.6 0.0 1.1e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMG46858.1 - 1e-17 64.3 0.1 3.9e-16 59.0 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EMG46858.1 - 4.8e-17 61.9 1.4 2.9e-16 59.3 0.2 2.4 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMG46858.1 - 1.1e-10 41.1 0.0 1.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EMG46858.1 - 1e-08 35.3 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EMG46858.1 - 2.5e-07 30.1 0.0 2.9e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 EMG46858.1 - 2.6e-06 27.0 0.0 4.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EMG46858.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 EMG46858.1 - 0.0042 16.7 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GalKase_gal_bdg PF10509.9 EMG46859.1 - 7.3e-19 67.1 0.1 1.4e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EMG46859.1 - 3.8e-16 59.1 0.2 8.7e-16 57.9 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMG46859.1 - 1.5e-11 44.5 0.0 3.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal SNF2_N PF00176.23 EMG46860.1 - 2.1e-61 207.6 0.0 3.4e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cdh1_DBD_1 PF18196.1 EMG46860.1 - 1e-33 116.2 1.5 1e-33 116.2 1.5 2.9 3 0 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 EMG46860.1 - 1.3e-27 96.1 0.5 1.3e-27 96.1 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 EMG46860.1 - 9.6e-24 83.1 7.2 2.5e-14 52.9 2.7 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EMG46860.1 - 2.4e-20 72.9 0.0 9.1e-20 71.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG46860.1 - 8.7e-11 42.1 0.2 4.7e-10 39.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EMG46860.1 - 1.6e-07 30.8 0.0 6.9e-07 28.7 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SLIDE PF09111.10 EMG46860.1 - 0.00028 20.9 0.2 0.027 14.5 0.0 3.2 2 0 0 2 2 2 1 SLIDE Staphostatin_B PF09023.10 EMG46860.1 - 0.024 14.7 0.1 7.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Staphostatin B SIT PF15330.6 EMG46860.1 - 8.9 6.8 7.0 1.6 9.2 1.8 2.4 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT ABC_tran PF00005.27 EMG46861.1 - 6.7e-36 123.8 0.0 1.4e-17 64.5 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 EMG46861.1 - 4.4e-12 45.6 5.7 1.1e-11 44.4 5.7 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 EMG46861.1 - 1.9e-10 40.5 4.0 0.00051 19.5 0.7 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMG46861.1 - 5.9e-09 36.2 6.3 0.19 11.5 0.9 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 EMG46861.1 - 2.4e-08 33.4 3.0 2.4e-08 33.4 3.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 EMG46861.1 - 5.5e-06 26.8 0.0 0.042 14.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_6 PF12837.7 EMG46861.1 - 4.4e-05 23.4 2.7 4.4e-05 23.4 2.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 EMG46861.1 - 0.00011 22.7 6.8 0.00082 19.9 0.3 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_16 PF13191.6 EMG46861.1 - 0.00023 21.6 0.0 0.37 11.1 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EMG46861.1 - 0.00023 21.1 0.0 0.97 9.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Fer4_21 PF14697.6 EMG46861.1 - 0.0004 20.5 12.3 0.00088 19.4 12.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_22 PF13401.6 EMG46861.1 - 0.00046 20.5 0.4 0.13 12.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EMG46861.1 - 0.001 18.9 5.3 0.15 11.7 0.5 3.4 3 2 0 4 4 4 1 AAA ATPase domain RNA_helicase PF00910.22 EMG46861.1 - 0.001 19.4 0.1 0.22 11.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 EMG46861.1 - 0.0013 18.7 0.1 0.43 10.5 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 EMG46861.1 - 0.0014 18.3 0.4 1.4 8.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fer4_10 PF13237.6 EMG46861.1 - 0.0025 17.9 1.3 0.0025 17.9 1.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EMG46861.1 - 0.0026 17.8 0.9 0.0026 17.8 0.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 EMG46861.1 - 0.0026 17.9 12.5 0.0054 16.9 12.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_18 PF13238.6 EMG46861.1 - 0.0029 18.1 0.1 4.6 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EMG46861.1 - 0.0032 17.2 1.3 0.38 10.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMG46861.1 - 0.0043 17.2 0.8 3.6 7.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 EMG46861.1 - 0.0047 16.9 1.5 1.2 9.0 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Fer4_16 PF13484.6 EMG46861.1 - 0.012 16.5 0.2 0.012 16.5 0.2 2.8 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain SRP54 PF00448.22 EMG46861.1 - 0.018 14.7 3.3 0.59 9.7 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EMG46861.1 - 0.021 14.5 0.4 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMG46861.1 - 0.026 14.8 0.1 10 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EMG46861.1 - 0.03 13.5 0.0 0.82 8.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_13 PF13166.6 EMG46861.1 - 0.031 12.9 0.5 0.068 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EMG46861.1 - 0.034 14.1 0.1 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 EMG46861.1 - 0.048 13.9 0.0 9.8 6.5 0.0 2.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_8 PF13183.6 EMG46861.1 - 0.049 14.1 5.0 0.15 12.5 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_25 PF13481.6 EMG46861.1 - 0.052 13.1 0.6 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 EMG46861.1 - 0.057 13.1 0.0 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E AAA_5 PF07728.14 EMG46861.1 - 0.095 12.7 0.7 1 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HflK_N PF12221.8 EMG46861.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal DnaB_C PF03796.15 EMG46861.1 - 0.11 11.8 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Thymidylate_kin PF02223.17 EMG46861.1 - 0.12 12.0 0.4 16 5.1 0.1 3.2 3 0 0 3 3 3 0 Thymidylate kinase AAA_23 PF13476.6 EMG46861.1 - 0.13 12.8 5.5 0.66 10.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMG46861.1 - 0.14 12.2 0.5 19 5.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain Fer4_4 PF12800.7 EMG46861.1 - 1.2 9.9 16.2 0.27 11.9 2.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 EMG46861.1 - 1.2 10.2 15.5 0.17 12.9 3.5 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 EMG46861.1 - 3.4 8.3 11.6 0.16 12.5 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Sec62 PF03839.16 EMG46862.1 - 1.8e-69 233.5 3.1 1.8e-69 233.5 3.1 2.3 2 0 0 2 2 2 1 Translocation protein Sec62 WD40 PF00400.32 EMG46862.1 - 2.7e-06 28.0 0.5 0.31 12.0 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG46862.1 - 0.016 15.4 0.0 1.3 9.3 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain NusG_II PF07009.11 EMG46862.1 - 0.093 12.9 0.1 3.7 7.8 0.0 2.7 2 0 0 2 2 2 0 NusG domain II NOA36 PF06524.12 EMG46862.1 - 9.6 5.4 7.0 20 4.4 7.0 1.4 1 0 0 1 1 1 0 NOA36 protein ECH_2 PF16113.5 EMG46863.1 - 5.2e-98 328.6 0.0 6.3e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EMG46863.1 - 2.5e-24 86.0 0.0 5.6e-23 81.5 0.0 2.2 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Imm44 PF15571.6 EMG46863.1 - 0.071 13.4 0.2 0.17 12.1 0.2 1.7 1 0 0 1 1 1 0 Immunity protein 44 Actin PF00022.19 EMG46864.1 - 5.9e-62 209.6 0.0 3.1e-49 167.7 0.0 2.3 2 0 0 2 2 2 2 Actin Peptidase_M16 PF00675.20 EMG46865.1 - 1.6e-45 154.7 0.0 3.1e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMG46865.1 - 1.5e-30 106.6 0.1 1.4e-29 103.4 0.0 2.5 3 1 0 3 3 3 1 Peptidase M16 inactive domain DUF725 PF05267.12 EMG46865.1 - 0.015 15.2 0.9 0.026 14.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF725) Syntaxin-6_N PF09177.11 EMG46865.1 - 0.6 10.7 3.4 3.2 8.4 0.3 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Ada3 PF10198.9 EMG46866.1 - 1.7e-40 138.2 5.3 1.7e-40 138.2 5.3 3.2 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Glyco_transf_20 PF00982.21 EMG46867.1 - 1.2e-148 495.8 0.2 1.5e-148 495.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EMG46867.1 - 3.7e-75 252.0 0.0 7.4e-75 251.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase RRM_1 PF00076.22 EMG46868.1 - 1.2e-84 278.1 7.2 1.6e-21 75.9 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EMG46868.1 - 1.3e-20 73.3 2.2 2.4e-19 69.2 0.2 3.3 4 0 0 4 4 4 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EMG46868.1 - 1.8e-06 27.6 0.0 0.046 13.3 0.0 3.9 2 2 2 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YflT PF11181.8 EMG46868.1 - 1.5e-05 25.4 4.0 0.013 16.0 0.4 3.1 3 0 0 3 3 3 2 Heat induced stress protein YflT Nup35_RRM_2 PF14605.6 EMG46868.1 - 7.5e-05 22.7 2.0 0.18 11.9 0.1 3.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.8 EMG46868.1 - 0.00091 19.3 0.0 1.8 8.8 0.0 3.4 3 0 0 3 3 3 1 Cobalamin biosynthesis central region RRM_occluded PF16842.5 EMG46868.1 - 0.0014 18.5 0.0 0.041 13.7 0.0 2.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EMG46868.1 - 0.0016 18.5 0.5 16 5.7 0.0 4.7 4 1 0 4 4 4 1 RNA recognition motif Nefa_Nip30_N PF10187.9 EMG46868.1 - 0.021 15.2 0.4 0.021 15.2 0.4 3.7 5 1 0 5 5 5 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 OB_RNB PF08206.11 EMG46868.1 - 0.029 14.0 0.9 4.9 6.9 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain DUF4523 PF15023.6 EMG46868.1 - 0.09 12.6 0.0 38 4.0 0.0 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF4523) Arrestin_C PF02752.22 EMG46869.1 - 5.7e-17 62.4 0.1 5.7e-17 62.4 0.1 3.2 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EMG46869.1 - 8.8e-09 35.6 0.0 0.00045 20.3 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Receptor_2B4 PF11465.8 EMG46869.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Abhydrolase_1 PF00561.20 EMG46870.1 - 3.3e-11 43.3 0.0 3.8e-10 39.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG46870.1 - 5.6e-08 32.4 0.0 1.1e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMG46870.1 - 0.00085 20.0 0.0 0.0013 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.11 EMG46870.1 - 0.098 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 EMG46870.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) 14-3-3 PF00244.20 EMG46871.1 - 1.2e-103 345.4 4.2 1.5e-103 345.1 4.2 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 EMG46871.1 - 0.019 15.0 0.4 0.047 13.7 0.4 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF Peptidase_M24 PF00557.24 EMG46872.1 - 6.7e-08 32.5 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.29 EMG46873.1 - 3.4e-10 39.7 6.7 1e-09 38.1 6.7 1.9 1 0 0 1 1 1 1 PHD-finger Ferrochelatase PF00762.19 EMG46873.1 - 0.076 12.1 0.3 0.32 10.0 0.3 2.0 2 1 0 2 2 2 0 Ferrochelatase TMPIT PF07851.13 EMG46873.1 - 0.96 8.6 6.0 1.8 7.7 6.0 1.5 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 EMG46873.1 - 5.4 7.7 13.8 0.16 12.6 6.2 2.4 3 0 0 3 3 3 0 Initiation control protein YabA RP-C_C PF11800.8 EMG46873.1 - 6.7 6.7 7.4 5.6 7.0 2.3 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region BORCS8 PF10167.9 EMG46873.1 - 8.2 6.4 9.8 0.87 9.5 5.0 1.8 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 MgsA_C PF12002.8 EMG46874.1 - 1.3e-56 191.1 0.0 5.4e-56 189.1 0.0 1.9 1 1 1 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EMG46874.1 - 2.2e-20 72.8 3.0 2.9e-20 72.4 0.1 2.5 2 1 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 EMG46874.1 - 6.1e-16 59.0 0.0 1.4e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMG46874.1 - 9.8e-16 57.9 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EMG46874.1 - 7.2e-06 26.0 0.5 0.00011 22.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMG46874.1 - 9.3e-06 25.9 0.0 3.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EMG46874.1 - 2e-05 25.0 1.2 0.0055 17.1 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 EMG46874.1 - 2.5e-05 24.0 0.0 0.00026 20.7 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.13 EMG46874.1 - 0.00011 21.6 0.1 0.00082 18.7 0.0 2.3 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 EMG46874.1 - 0.00012 22.1 0.1 0.00052 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zn-C2H2_12 PF18112.1 EMG46874.1 - 0.00069 20.0 0.3 0.002 18.5 0.3 1.8 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2 PF00096.26 EMG46874.1 - 0.0033 17.8 0.4 0.0071 16.7 0.4 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type Sigma54_activ_2 PF14532.6 EMG46874.1 - 0.0042 17.2 0.0 0.0086 16.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RNF220 PF15926.5 EMG46874.1 - 0.0043 16.7 0.7 0.0043 16.7 0.7 2.5 2 1 1 3 3 2 1 E3 ubiquitin-protein ligase RNF220 Mg_chelatase PF01078.21 EMG46874.1 - 0.0052 16.2 0.1 1.3 8.4 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EMG46874.1 - 0.013 14.7 0.0 0.042 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) zf-C2H2_4 PF13894.6 EMG46874.1 - 0.017 15.9 1.6 0.045 14.6 1.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger AAA_22 PF13401.6 EMG46874.1 - 0.027 14.8 0.2 0.44 10.8 0.2 2.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMG46874.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-Di19 PF05605.12 EMG46874.1 - 0.031 14.6 0.5 0.066 13.5 0.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 EMG46874.1 - 0.039 13.9 1.0 0.07 13.0 1.0 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type AAA_3 PF07726.11 EMG46874.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EMG46874.1 - 0.087 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 EMG46874.1 - 6.6 7.2 6.3 1.5 9.3 0.1 3.1 3 1 0 3 3 3 0 ABC transporter TFIIB PF00382.19 EMG46875.1 - 4.7e-41 138.7 0.0 6e-21 74.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EMG46875.1 - 4e-13 48.6 1.1 7.1e-13 47.9 1.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 EMG46875.1 - 0.0053 16.1 0.7 0.19 11.2 0.0 2.5 2 0 0 2 2 2 1 zinc-ribbon domain DUF2824 PF11039.8 EMG46875.1 - 0.012 15.6 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2824) Fungal_trans PF04082.18 EMG46876.1 - 2.1e-17 63.1 0.4 2.1e-17 63.1 0.4 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG46876.1 - 1.3e-08 34.8 11.6 3.9e-08 33.3 11.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tropomyosin PF00261.20 EMG46876.1 - 0.0047 16.3 0.1 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Tropomyosin Rad51 PF08423.11 EMG46876.1 - 0.015 14.6 0.2 0.048 12.9 0.1 1.8 2 0 0 2 2 2 0 Rad51 GPS2_interact PF15784.5 EMG46876.1 - 0.11 13.0 0.2 0.26 11.8 0.2 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Zn_clus PF00172.18 EMG46877.1 - 1.9e-08 34.3 7.5 3.2e-08 33.6 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serinc PF03348.15 EMG46877.1 - 0.051 12.5 8.1 0.11 11.4 8.1 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) UPF0506 PF11703.8 EMG46877.1 - 0.42 11.0 2.4 0.82 10.1 2.4 1.4 1 0 0 1 1 1 0 UPF0506 Merozoite_SPAM PF07133.11 EMG46877.1 - 0.52 10.3 22.6 0.015 15.3 9.2 2.6 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) BNIP2 PF12496.8 EMG46877.1 - 0.66 10.4 10.3 0.13 12.7 1.6 3.0 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 EOS1 PF12326.8 EMG46877.1 - 4.1 7.3 6.4 1.8 8.4 2.8 2.4 2 0 0 2 2 2 0 N-glycosylation protein CobT PF06213.12 EMG46877.1 - 7.1 5.9 24.9 0.037 13.4 15.5 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Septin PF00735.18 EMG46878.1 - 4.4e-113 377.2 0.1 4.4e-113 377.2 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EMG46878.1 - 1.5e-07 31.5 0.0 4.6e-07 29.9 0.0 1.8 2 0 0 2 2 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMG46878.1 - 0.0001 22.2 5.3 0.0017 18.3 0.3 3.6 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EMG46878.1 - 0.0013 18.3 1.0 0.028 14.0 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EMG46878.1 - 0.0024 18.0 0.0 0.0068 16.6 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 EMG46878.1 - 0.0046 16.1 0.0 0.0094 15.0 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 EMG46878.1 - 0.0054 17.1 0.1 0.022 15.1 0.0 2.0 3 0 0 3 3 2 1 AAA ATPase domain KAP_NTPase PF07693.14 EMG46878.1 - 0.0073 15.6 0.0 0.024 13.9 0.0 1.9 1 1 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 EMG46878.1 - 0.011 16.0 0.2 0.036 14.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EMG46878.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EMG46878.1 - 0.022 14.5 0.3 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMG46878.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 EMG46878.1 - 0.043 13.2 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 EMG46878.1 - 0.05 13.7 7.8 6.2 6.9 0.0 3.4 2 1 1 3 3 3 0 Dynamin family DUF5082 PF16888.5 EMG46878.1 - 0.062 13.6 4.5 0.11 12.8 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) ABC_tran PF00005.27 EMG46878.1 - 0.076 13.5 0.7 0.29 11.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Pox_A32 PF04665.12 EMG46878.1 - 0.081 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 EMG46878.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region XhlA PF10779.9 EMG46878.1 - 0.13 12.5 2.8 0.3 11.3 2.8 1.7 1 0 0 1 1 1 0 Haemolysin XhlA RNA_helicase PF00910.22 EMG46878.1 - 0.16 12.4 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Recep_L_domain PF01030.24 EMG46879.1 - 8.1e-07 29.2 5.2 0.012 15.7 0.1 4.2 1 1 3 4 4 4 4 Receptor L domain Ima1_N PF09779.9 EMG46879.1 - 0.081 13.8 2.8 0.16 12.9 2.8 1.4 1 0 0 1 1 1 0 Ima1 N-terminal domain DASH_Spc19 PF08287.11 EMG46880.1 - 1.2e-38 132.5 12.7 1.3e-38 132.3 12.7 1.0 1 0 0 1 1 1 1 Spc19 KELK PF15796.5 EMG46880.1 - 0.034 14.6 0.1 0.034 14.6 0.1 2.4 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase WXG100 PF06013.12 EMG46880.1 - 0.046 13.9 0.2 0.45 10.8 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF4140 PF13600.6 EMG46880.1 - 0.4 11.2 4.8 0.75 10.3 1.0 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HSF_DNA-bind PF00447.17 EMG46881.1 - 0.11 13.1 1.2 0.59 10.8 1.2 2.2 1 1 0 1 1 1 0 HSF-type DNA-binding DUF3340 PF11818.8 EMG46881.1 - 0.52 10.5 12.6 0.46 10.6 6.1 2.7 1 1 1 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Type2_restr_D3 PF16902.5 EMG46881.1 - 0.66 9.9 3.0 8.7 6.3 0.5 3.0 1 1 2 3 3 3 0 Type-2 restriction enzyme D3 domain Nup54_57_C PF18570.1 EMG46881.1 - 0.93 9.1 7.3 52 3.5 0.0 4.9 5 0 0 5 5 5 0 NUP57/Nup54 C-terminal domain PRP1_N PF06424.12 EMG46881.1 - 2.1 8.7 5.5 27 5.1 0.3 2.9 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal Fib_alpha PF08702.10 EMG46881.1 - 7.1 6.8 7.2 7.6 6.7 2.3 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family VHS PF00790.19 EMG46882.1 - 2.3e-41 140.9 0.0 7e-41 139.4 0.0 1.8 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 EMG46882.1 - 1.7e-19 70.2 1.0 1.7e-19 70.2 1.0 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 EMG46882.1 - 3.2e-16 59.4 0.1 1.7e-15 57.1 0.1 2.3 1 0 0 1 1 1 1 GAT domain GGA_N-GAT PF18308.1 EMG46882.1 - 2.4e-06 27.0 0.1 8.2e-06 25.3 0.1 2.0 1 0 0 1 1 1 1 GGA N-GAT domain DUF4112 PF13430.6 EMG46884.1 - 1e-34 119.0 0.3 1.4e-34 118.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Coq4 PF05019.13 EMG46885.1 - 4.6e-94 313.9 0.0 5.9e-94 313.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Chordopox_G2 PF05796.12 EMG46885.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus protein G2 PXA PF02194.15 EMG46886.1 - 1.6e-24 86.9 6.8 1.6e-24 86.9 6.8 2.4 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EMG46886.1 - 0.00065 20.3 1.4 0.0023 18.5 0.1 2.7 2 0 0 2 2 2 1 Sorting nexin C terminal NAAA-beta PF15508.6 EMG46886.1 - 0.0065 16.8 0.4 5.2 7.5 0.0 3.2 2 0 0 2 2 2 2 beta subunit of N-acylethanolamine-hydrolyzing acid amidase BPL_LplA_LipB PF03099.19 EMG46887.1 - 3.1e-10 40.0 0.0 4.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DHHC PF01529.20 EMG46888.1 - 9.9e-33 113.1 20.2 9.9e-33 113.1 20.2 2.6 3 0 0 3 3 3 1 DHHC palmitoyltransferase DUF4512 PF14975.6 EMG46888.1 - 0.003 18.3 0.0 0.13 13.0 0.0 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4512) DUF881 PF05949.12 EMG46889.1 - 0.053 13.4 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF881) CybS PF05328.12 EMG46890.1 - 2.3e-54 182.7 0.0 3.5e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit KH_8 PF17903.1 EMG46891.1 - 0.084 13.0 1.4 1.1 9.4 0.1 2.9 2 1 1 3 3 3 0 Krr1 KH1 domain FHA PF00498.26 EMG46892.1 - 2.4e-15 56.6 0.6 1.6e-14 54.0 0.0 2.8 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 EMG46892.1 - 0.00018 21.8 0.0 0.0006 20.1 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Sen15 PF09631.10 EMG46893.1 - 2.5e-26 91.9 0.2 2.8e-26 91.7 0.2 1.0 1 0 0 1 1 1 1 Sen15 protein Globin PF00042.22 EMG46894.1 - 6.5e-06 26.7 0.1 0.00016 22.2 0.0 3.0 3 1 0 3 3 3 1 Globin DASH_Dad2 PF08654.10 EMG46895.1 - 0.095 13.1 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad2 PUF PF00806.19 EMG46897.1 - 1.1e-28 97.3 6.9 0.003 17.2 0.0 8.7 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat EXOSC1 PF10447.9 EMG46898.1 - 1.2e-37 128.9 1.5 1.2e-37 128.8 0.2 1.7 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 CSD2 PF17876.1 EMG46898.1 - 0.055 13.6 0.5 0.39 10.9 0.2 2.4 3 0 0 3 3 3 0 Cold shock domain tRNA-synt_2 PF00152.20 EMG46899.1 - 2.4e-101 339.0 0.1 3.1e-101 338.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMG46899.1 - 2.9e-07 30.4 0.0 7.7e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMG46899.1 - 0.029 13.8 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) NUDIX PF00293.28 EMG46900.1 - 1.9e-11 44.1 0.0 3.1e-11 43.4 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain Glyco_transf_15 PF01793.16 EMG46901.1 - 4.5e-127 423.8 17.6 6.1e-127 423.3 17.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase zf-AN1 PF01428.16 EMG46902.1 - 3.3e-11 43.1 11.9 5.1e-11 42.5 11.9 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EMG46902.1 - 0.12 12.7 5.1 0.1 13.0 3.4 1.7 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Retrotran_gag_2 PF14223.6 EMG46903.1 - 0.12 12.0 0.3 0.49 10.1 0.3 1.9 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Elongin_A PF06881.11 EMG46905.1 - 1.8e-28 99.1 3.1 3.1e-28 98.4 3.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ETRAMP PF09716.10 EMG46905.1 - 4.6 7.4 5.9 0.74 9.9 1.7 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CRAL_TRIO PF00650.20 EMG46906.1 - 1.1e-21 77.2 0.0 1.8e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMG46906.1 - 1.3e-17 63.6 1.0 3e-17 62.5 1.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyco_hydro_20 PF00728.22 EMG46907.1 - 8.1e-96 321.5 0.0 1e-95 321.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EMG46907.1 - 3.7e-19 69.8 0.0 6.9e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EMG46907.1 - 0.00017 22.4 0.0 0.00029 21.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF5437 PF17505.2 EMG46907.1 - 0.22 11.6 0.3 0.41 10.7 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5437) HORMA PF02301.18 EMG46908.1 - 9.4e-20 71.1 0.2 1.4e-19 70.6 0.2 1.3 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EMG46908.1 - 0.0021 18.1 0.9 0.017 15.1 0.9 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 Arcadin_1 PF18653.1 EMG46908.1 - 0.0073 16.4 1.4 2.1 8.4 0.0 2.2 1 1 1 2 2 2 2 Arcadin 1 DUF1682 PF07946.14 EMG46908.1 - 0.026 13.7 0.1 0.028 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PPTA PF01239.22 EMG46909.1 - 2.3e-40 135.1 16.6 8.8e-09 34.8 2.5 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat NYD-SP28_assoc PF14775.6 EMG46909.1 - 0.032 14.3 2.2 0.54 10.4 0.0 3.6 4 0 0 4 4 4 0 Sperm tail C-terminal domain Peripla_BP_7 PF18610.1 EMG46909.1 - 0.1 12.8 3.1 0.14 12.3 0.3 2.6 3 0 0 3 3 3 0 Periplasmic binding protein domain Syntaxin_2 PF14523.6 EMG46909.1 - 0.27 11.6 9.2 2.2 8.7 1.7 2.6 2 0 0 2 2 2 0 Syntaxin-like protein DUF4246 PF14033.6 EMG46910.1 - 3.6e-136 454.9 2.3 4.7e-136 454.5 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Porin_3 PF01459.22 EMG46912.1 - 5.9e-73 245.7 7.5 6.6e-73 245.5 7.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin RRM_1 PF00076.22 EMG46913.1 - 2e-16 59.5 0.1 4e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macro_2 PF14519.6 EMG46915.1 - 4.9e-14 52.3 3.0 1.3e-13 50.9 3.0 1.7 1 1 0 1 1 1 1 Macro-like domain NUDIX PF00293.28 EMG46915.1 - 3.3e-07 30.4 0.0 7.8e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain Macro PF01661.21 EMG46915.1 - 0.018 15.0 0.0 0.049 13.7 0.0 1.7 2 0 0 2 2 2 0 Macro domain Lip_prot_lig_C PF10437.9 EMG46915.1 - 0.078 13.0 0.0 0.27 11.3 0.0 2.0 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus BOP1NT PF08145.12 EMG46916.1 - 2.7e-105 352.0 8.4 5.3e-105 351.0 8.4 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EMG46916.1 - 6.2e-23 80.7 5.6 1.9e-09 38.0 0.2 6.9 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG46916.1 - 2.9e-06 27.5 0.2 0.0048 17.2 0.0 3.9 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RPA43_OB PF17875.1 EMG46916.1 - 0.53 10.9 7.9 1.3 9.7 0.1 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I PGAP1 PF07819.13 EMG46917.1 - 1.7e-48 165.3 0.0 6.9e-46 156.8 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 EMG46917.1 - 2.2e-08 34.3 0.0 2.5e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EMG46917.1 - 2.7e-07 30.5 0.0 5.7e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG46917.1 - 6.3e-07 28.9 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMG46917.1 - 9.6e-06 26.3 0.0 2.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EMG46917.1 - 2.6e-05 23.8 0.0 5.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 EMG46917.1 - 0.00015 21.4 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase LCAT PF02450.15 EMG46917.1 - 0.00053 19.3 0.0 0.00071 18.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.7 EMG46917.1 - 0.00076 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EMG46917.1 - 0.0014 18.3 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 EMG46917.1 - 0.0025 17.8 0.0 0.0055 16.6 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.8 EMG46917.1 - 0.004 16.7 0.0 0.0053 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_2 PF01674.18 EMG46917.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_2 PF02230.16 EMG46917.1 - 0.027 14.3 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 EMG46917.1 - 0.031 14.1 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF915 PF06028.11 EMG46917.1 - 0.067 12.5 0.0 4.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_8 PF06259.12 EMG46917.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Thioesterase PF00975.20 EMG46917.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 EMG46917.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2235 PF09994.9 EMG46917.1 - 0.19 11.0 0.0 0.36 10.2 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Septin PF00735.18 EMG46918.1 - 2.5e-110 368.2 3.7 2.5e-110 368.2 3.7 1.6 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 EMG46918.1 - 3.9e-05 23.6 3.5 0.0078 16.1 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 EMG46918.1 - 0.0015 18.6 1.1 0.0025 17.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMG46918.1 - 0.018 14.6 7.3 0.026 14.1 0.1 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Strep_SA_rep PF06696.11 EMG46918.1 - 0.029 14.4 0.7 0.029 14.4 0.7 2.2 2 0 0 2 2 2 0 Streptococcal surface antigen repeat AAA_16 PF13191.6 EMG46918.1 - 0.035 14.5 0.5 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EMG46918.1 - 0.038 14.5 2.4 0.22 12.0 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 EMG46918.1 - 0.049 13.9 0.5 0.39 11.0 0.0 2.6 2 2 0 2 2 2 0 AAA domain AIG1 PF04548.16 EMG46918.1 - 0.063 12.6 0.1 0.063 12.6 0.1 2.1 2 0 0 2 2 2 0 AIG1 family PduV-EutP PF10662.9 EMG46918.1 - 0.077 12.7 0.1 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EMG46918.1 - 0.11 12.8 0.7 0.29 11.4 0.1 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EMG46918.1 - 0.3 10.8 3.7 0.18 11.5 0.2 2.2 2 1 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 EMG46918.1 - 1.7 8.2 8.2 2.9 7.4 8.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 EMG46918.1 - 5.9 6.1 10.7 2.9 7.2 8.4 1.7 2 0 0 2 2 2 0 FAM76 protein UPF0121 PF03661.13 EMG46919.1 - 5.2e-20 71.9 7.8 6.7e-20 71.5 7.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) AP3D1 PF06375.11 EMG46920.1 - 0.0055 17.0 1.7 0.0081 16.4 1.7 1.3 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 DUF2240 PF09999.9 EMG46920.1 - 0.016 14.8 0.5 0.07 12.8 0.5 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) Proteasom_Rpn13 PF04683.13 EMG46921.1 - 1.6e-23 83.0 0.0 2.7e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EMG46921.1 - 4.3e-07 30.1 0.1 0.0002 21.5 0.0 2.2 1 1 1 2 2 2 2 UCH-binding domain Fur_reg_FbpA PF13076.6 EMG46921.1 - 3.2 7.5 7.6 1.5 8.6 0.3 3.0 4 0 0 4 4 4 0 Fur-regulated basic protein A CinA PF02464.17 EMG46922.1 - 1.5e-29 102.5 0.0 3.4e-22 78.7 0.0 2.0 2 0 0 2 2 2 2 Competence-damaged protein AMP-binding PF00501.28 EMG46924.1 - 1.4e-87 294.1 0.0 1.7e-87 293.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMG46924.1 - 1e-25 90.5 1.4 5.4e-25 88.2 1.4 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EMG46924.1 - 7.3e-17 61.0 0.2 2.2e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Mannosyl_trans2 PF04188.13 EMG46925.1 - 7.8e-34 117.7 20.3 8.9e-27 94.5 8.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) DUF3445 PF11927.8 EMG46926.1 - 7.6e-72 241.6 0.0 9.6e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Histone PF00125.24 EMG46927.1 - 5.7e-45 152.9 0.2 6.1e-45 152.8 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EMG46927.1 - 2.9e-06 27.5 0.0 4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EMG46927.1 - 3.9e-05 23.7 0.1 4.9e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EMG46927.1 - 0.0066 16.7 0.1 0.0095 16.2 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EMG46927.1 - 0.13 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HSP70 PF00012.20 EMG46928.1 - 3.4e-09 35.4 12.0 3.8e-09 35.3 12.0 1.0 1 0 0 1 1 1 1 Hsp70 protein TAF4 PF05236.14 EMG46928.1 - 0.00022 21.1 3.2 0.00024 21.0 3.2 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Cnd1_N PF12922.7 EMG46928.1 - 0.0045 16.9 5.1 0.0058 16.5 5.1 1.0 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Golgin_A5 PF09787.9 EMG46928.1 - 0.61 9.5 8.1 0.77 9.2 8.1 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3605 PF12239.8 EMG46929.1 - 1.3e-46 158.7 11.5 1.5e-46 158.5 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Ubiquitin_4 PF18036.1 EMG46929.1 - 0.0084 16.1 1.0 0.0084 16.1 1.0 1.8 2 0 0 2 2 2 1 Ubiquitin-like domain adh_short PF00106.25 EMG46930.1 - 9.7e-40 136.1 0.2 1.2e-39 135.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG46930.1 - 3e-31 108.8 0.0 3.9e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG46930.1 - 1.1e-09 38.5 0.1 1.4e-09 38.1 0.1 1.1 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 EMG46930.1 - 4.5e-05 23.7 0.2 0.00015 22.0 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.17 EMG46930.1 - 0.0011 19.4 0.3 0.0021 18.6 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EMG46930.1 - 0.0059 16.9 0.1 0.0095 16.2 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMG46930.1 - 0.035 14.2 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PQ-loop PF04193.14 EMG46931.1 - 1.1e-11 44.3 13.9 1.1e-08 34.7 2.6 2.9 3 0 0 3 3 3 2 PQ loop repeat zf-C2H2 PF00096.26 EMG46932.1 - 4e-06 27.0 3.4 0.0096 16.3 0.6 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG46932.1 - 0.019 15.8 4.9 2.4 9.2 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 EMG46932.1 - 0.047 14.0 0.1 0.16 12.3 0.1 2.0 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 EMG46932.1 - 0.06 13.5 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 EMG46932.1 - 6.1 7.3 7.4 4 7.9 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding His_Phos_1 PF00300.22 EMG46933.1 - 1.5e-31 109.7 0.0 2.3e-22 79.6 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) adh_short PF00106.25 EMG46935.1 - 1e-43 149.1 0.5 1.2e-43 148.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG46935.1 - 1.2e-32 113.4 0.0 1.3e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG46935.1 - 7e-12 45.6 0.1 8.7e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMG46935.1 - 5.4e-07 29.7 0.0 8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 EMG46935.1 - 1.9e-06 28.1 0.1 3.3e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 EMG46935.1 - 0.0043 16.1 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EMG46935.1 - 0.0064 16.7 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 EMG46935.1 - 0.0099 15.5 0.7 0.018 14.6 0.7 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EMG46935.1 - 0.071 12.2 0.1 0.1 11.7 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 EMG46935.1 - 0.11 13.3 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.20 EMG46935.1 - 0.15 12.1 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 EMG46936.1 - 1.9e-43 148.7 0.1 2.4e-43 148.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMG46936.1 - 6.3e-41 140.0 1.2 7.6e-41 139.7 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG46936.1 - 3.5e-13 49.8 0.2 7.5e-13 48.8 0.2 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMG46936.1 - 0.0044 16.4 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EMG46936.1 - 0.029 13.5 0.2 0.044 12.9 0.2 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein RRM_1 PF00076.22 EMG46938.1 - 8.8e-54 179.2 0.5 7e-15 54.6 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMG46938.1 - 5e-08 32.9 0.2 0.031 14.4 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif RRM_Rrp7 PF17799.1 EMG46938.1 - 0.00052 19.8 0.3 2.3 8.0 0.0 3.9 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain SID-1_RNA_chan PF13965.6 EMG46938.1 - 0.75 8.1 4.0 1.4 7.2 4.0 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Metallophos PF00149.28 EMG46939.1 - 3.5e-37 128.9 0.1 4.7e-37 128.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 EMG46939.1 - 0.089 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Glyco_hydro_65N PF03636.15 EMG46939.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Ribosomal_S18 PF01084.20 EMG46940.1 - 4.2e-15 55.7 0.0 1.1e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S18 Pinin_SDK_memA PF04696.13 EMG46940.1 - 0.015 15.4 0.5 0.028 14.5 0.5 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region IATP PF04568.12 EMG46941.1 - 7.1e-12 45.6 2.1 7.8e-12 45.5 2.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Fib_alpha PF08702.10 EMG46941.1 - 0.0095 16.1 0.8 0.0095 16.1 0.8 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family CRISPR_Cas2 PF09827.9 EMG46941.1 - 0.036 14.2 1.0 0.079 13.2 1.0 1.6 1 1 0 1 1 1 0 CRISPR associated protein Cas2 PilO PF04350.13 EMG46941.1 - 0.05 13.8 6.5 0.066 13.4 6.5 1.1 1 0 0 1 1 1 0 Pilus assembly protein, PilO Calici_MSP PF05752.11 EMG46941.1 - 0.058 13.2 0.5 0.068 13.0 0.5 1.1 1 0 0 1 1 1 0 Calicivirus minor structural protein PspB PF06667.12 EMG46941.1 - 0.14 12.2 2.5 0.2 11.8 2.5 1.2 1 0 0 1 1 1 0 Phage shock protein B Glutaredoxin2_C PF04399.13 EMG46941.1 - 0.38 10.6 3.6 0.76 9.6 3.6 1.6 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain DivIC PF04977.15 EMG46941.1 - 2.4 8.0 9.5 2.8 7.8 9.0 1.4 1 1 0 1 1 1 0 Septum formation initiator UIM PF02809.20 EMG46942.1 - 0.0042 16.9 1.7 0.011 15.6 1.7 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif MRP-S25 PF13741.6 EMG46942.1 - 2 7.9 7.9 4.4 6.8 5.7 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S25 CLTH PF10607.9 EMG46943.1 - 1.2e-26 93.3 15.0 1.2e-26 93.3 15.0 3.0 2 2 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain DDHD PF02862.17 EMG46943.1 - 0.015 15.4 1.7 0.039 14.1 1.7 1.6 1 0 0 1 1 1 0 DDHD domain Phasin PF05597.11 EMG46943.1 - 0.016 15.2 0.8 0.038 14.0 0.8 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PyrI_C PF02748.15 EMG46943.1 - 0.017 15.0 1.2 0.043 13.7 1.2 1.8 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ERAP1_C PF11838.8 EMG46944.1 - 2.9e-84 283.3 0.1 1.5e-82 277.7 0.1 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EMG46944.1 - 1e-79 267.1 0.8 1.6e-79 266.5 0.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EMG46944.1 - 5.6e-53 179.9 2.3 1.1e-52 178.9 1.8 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Calycin_like PF13944.6 EMG46944.1 - 0.015 15.6 1.4 0.038 14.3 1.4 1.6 1 0 0 1 1 1 0 Calycin-like beta-barrel domain BSP PF04450.12 EMG46944.1 - 0.11 12.3 0.1 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Peptidase of plants and bacteria SprT-like PF10263.9 EMG46944.1 - 0.17 11.7 0.0 0.56 10.1 0.0 1.8 1 0 0 1 1 1 0 SprT-like family Rotamase PF00639.21 EMG46945.1 - 7.1e-23 81.4 0.0 1e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EMG46945.1 - 1.3e-19 70.9 0.0 1.8e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EMG46945.1 - 1.6e-08 34.5 1.7 2.9e-08 33.6 1.7 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 EMG46945.1 - 1.9e-05 25.5 0.0 5.1e-05 24.1 0.0 1.7 1 1 1 2 2 2 1 PPIC-type PPIASE domain Vac_Fusion PF02346.16 EMG46945.1 - 0.083 12.5 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 ADK PF00406.22 EMG46946.1 - 1.7e-45 154.8 0.1 2.5e-45 154.3 0.1 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EMG46946.1 - 3.4e-35 121.4 0.1 4.6e-35 121.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMG46946.1 - 7.4e-08 33.0 0.0 1.2e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMG46946.1 - 6.2e-06 26.4 0.0 1.8e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EMG46946.1 - 0.0022 17.3 0.0 0.0046 16.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin VraX PF17412.2 EMG46946.1 - 0.17 11.5 0.2 0.4 10.3 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function CENP-N PF05238.13 EMG46947.1 - 6.9e-93 312.2 2.1 8.2e-93 312.0 2.1 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Vps16_N PF04841.13 EMG46948.1 - 4.7e-48 163.9 3.9 1.3e-22 80.2 0.0 3.3 2 1 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.12 EMG46948.1 - 3.3e-37 128.2 10.4 5.3e-20 71.7 4.7 2.4 2 0 0 2 2 2 2 Vps16, C-terminal region Phage_int_SAM_3 PF14659.6 EMG46948.1 - 6.8 7.0 7.9 6 7.2 0.2 3.7 3 1 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain CT_C_D PF02682.16 EMG46949.1 - 0.00033 20.5 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D CT_C_D PF02682.16 EMG46950.1 - 6.4e-23 81.6 0.0 8.2e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D CT_A_B PF02626.15 EMG46951.1 - 6e-70 235.9 0.0 6.7e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B SSF PF00474.17 EMG46952.1 - 3.1e-05 23.0 1.3 3.1e-05 23.0 1.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family AdoMet_MTase PF07757.13 EMG46953.1 - 6.8e-41 139.1 0.2 1.2e-40 138.3 0.2 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase SHNi-TPR PF10516.9 EMG46954.1 - 5.5e-17 60.9 0.6 1.5e-16 59.5 0.5 1.8 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 EMG46954.1 - 0.025 14.8 1.4 0.046 14.0 0.0 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMG46954.1 - 0.12 12.6 2.4 2.1 8.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ICL PF00463.21 EMG46955.1 - 0 1047.0 2.6 0 1046.9 2.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EMG46955.1 - 1.9e-10 40.6 0.0 3.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF1635 PF07795.11 EMG46956.1 - 0.1 12.5 2.9 0.17 11.7 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SR-25 PF10500.9 EMG46956.1 - 5.8 6.5 16.6 10 5.7 16.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rrn6 PF10214.9 EMG46956.1 - 7 5.0 11.0 13 4.1 11.0 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Pkinase PF00069.25 EMG46957.1 - 3.1e-77 259.5 0.0 3.9e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG46957.1 - 4.4e-36 124.5 0.0 6.4e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMG46957.1 - 0.0014 17.6 0.0 0.013 14.5 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EMG46957.1 - 0.052 12.9 0.3 0.13 11.6 0.3 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMG46957.1 - 0.056 12.7 0.3 0.11 11.8 0.3 1.7 1 1 0 1 1 1 0 Kinase-like DUF1132 PF06575.12 EMG46958.1 - 0.0065 16.8 0.3 0.021 15.2 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1132) CNH PF00780.22 EMG46959.1 - 2.9e-14 53.3 0.0 7.8e-14 51.9 0.0 1.7 1 1 0 1 1 1 1 CNH domain PH_5 PF15405.6 EMG46959.1 - 6.7e-08 32.7 0.0 2e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EMG46959.1 - 9.9e-07 29.2 0.0 3.3e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 EMG46959.1 - 0.00029 21.1 1.9 0.00056 20.2 1.9 1.5 1 0 0 1 1 1 1 RhoGEF domain OGG_N PF07934.12 EMG46959.1 - 0.054 13.6 0.4 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain Abhydrolase_1 PF00561.20 EMG46960.1 - 1.4e-16 60.9 0.0 2.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMG46960.1 - 7e-14 53.0 0.0 1.1e-13 52.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMG46960.1 - 9.5e-13 48.0 0.0 3.6e-12 46.1 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EMG46960.1 - 1.3e-10 41.3 0.2 2e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 EMG46960.1 - 4.4e-07 29.8 0.1 1.6e-06 28.0 0.1 1.9 1 1 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.13 EMG46960.1 - 3.9e-06 26.8 0.0 1.5e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_2 PF02230.16 EMG46960.1 - 4.1e-06 26.8 0.1 0.015 15.2 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 EMG46960.1 - 5.4e-05 22.2 0.1 0.00011 21.2 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 EMG46960.1 - 8.1e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 EMG46960.1 - 0.00013 21.8 0.1 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EMG46960.1 - 0.0011 19.2 0.0 0.03 14.4 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain DUF676 PF05057.14 EMG46960.1 - 0.0012 18.3 2.4 0.0024 17.4 0.8 2.2 2 1 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 EMG46960.1 - 0.0018 18.1 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 EMG46960.1 - 0.015 14.5 0.1 0.12 11.5 0.0 2.3 2 1 1 3 3 3 0 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 EMG46960.1 - 0.03 13.4 0.0 0.071 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) PAF-AH_p_II PF03403.13 EMG46960.1 - 0.041 12.4 0.1 5 5.5 0.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF1057 PF06342.12 EMG46960.1 - 0.041 12.9 0.0 0.086 11.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF900 PF05990.12 EMG46960.1 - 0.067 12.7 0.1 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.21 EMG46960.1 - 0.07 12.6 0.0 5.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 EMG46960.1 - 0.12 12.3 0.0 0.45 10.4 0.0 2.0 1 1 1 2 2 2 0 Lipase (class 3) DLH PF01738.18 EMG46960.1 - 0.14 11.7 0.0 0.42 10.1 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family PhoLip_ATPase_C PF16212.5 EMG46961.1 - 3.6e-48 164.5 20.9 3.6e-48 164.5 20.9 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMG46961.1 - 2e-17 62.6 6.1 5.7e-17 61.2 6.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EMG46961.1 - 8.1e-12 45.0 0.3 8.1e-12 45.0 0.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMG46961.1 - 1.2e-10 42.1 0.3 0.0001 22.7 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMG46961.1 - 1.9e-07 31.1 0.0 1.5e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EMG46961.1 - 0.00069 19.4 0.1 0.0021 17.9 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Prot_ATP_ID_OB PF16450.5 EMG46961.1 - 0.085 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain ATP-synt_ab PF00006.25 EMG46963.1 - 2e-71 240.0 0.0 2.9e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EMG46963.1 - 1.4e-46 157.9 0.7 2.5e-46 157.1 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EMG46963.1 - 2.2e-17 63.3 0.7 6.1e-17 61.9 0.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 EMG46963.1 - 0.052 13.8 0.0 0.71 10.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain SSF PF00474.17 EMG46965.1 - 1.2e-05 24.4 5.1 1.3e-05 24.3 5.1 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family FGGY_N PF00370.21 EMG46966.1 - 1.8e-16 60.5 0.0 1e-10 41.6 0.0 2.8 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EMG46966.1 - 4.9e-11 42.7 0.0 1.1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain zf-C3H2C3 PF17122.5 EMG46967.1 - 4.7e-19 68.1 12.5 8.8e-19 67.2 12.5 1.5 1 0 0 1 1 1 1 Zinc-finger ANAPC4_WD40 PF12894.7 EMG46967.1 - 0.011 16.0 0.0 7.1 7.0 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 PF13923.6 EMG46967.1 - 0.029 14.2 8.9 0.06 13.2 8.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMG46967.1 - 0.035 14.4 6.3 0.084 13.2 6.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EMG46967.1 - 0.5 10.4 8.2 1.1 9.3 8.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain 2-Hacid_dh_C PF02826.19 EMG46968.1 - 3.1e-37 127.6 0.0 4.6e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMG46968.1 - 1.7e-13 50.4 0.0 2.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMG46968.1 - 0.00041 20.5 0.1 0.0019 18.4 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EMG46968.1 - 0.0064 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 EMG46968.1 - 0.031 13.9 0.3 0.12 12.0 0.3 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EMG46968.1 - 0.042 14.4 0.0 0.095 13.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 EMG46968.1 - 0.053 14.3 0.2 0.19 12.5 0.2 1.9 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 EMG46968.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding PUF PF00806.19 EMG46969.1 - 1.8e-62 203.7 17.1 1.1e-07 31.1 0.4 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EMG46969.1 - 0.00025 21.4 0.3 1.8 8.9 0.1 4.0 2 1 1 3 3 3 2 CPL (NUC119) domain sCache_2 PF17200.4 EMG46969.1 - 0.089 12.6 0.2 1.2e+02 2.5 0.0 4.2 4 1 1 5 5 5 0 Single Cache domain 2 Tom5 PF10642.9 EMG46969.1 - 0.27 11.3 3.8 0.98 9.5 3.8 2.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase BRAP2 PF07576.12 EMG46970.1 - 2.2e-05 24.6 0.3 0.00014 22.0 0.0 2.1 2 0 0 2 2 2 1 BRCA1-associated protein 2 RRM_1 PF00076.22 EMG46970.1 - 0.016 15.0 0.1 0.88 9.4 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EMG46971.1 - 8.4e-05 23.3 4.0 0.2 12.6 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG46971.1 - 0.0046 17.2 1.3 0.4 11.0 0.0 3.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 EMG46972.1 - 2.7e-29 98.9 24.2 6.5e-05 22.8 0.1 11.4 12 0 0 12 12 12 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG46972.1 - 4.4e-26 90.9 17.3 1.1e-21 76.8 0.0 5.8 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EMG46972.1 - 4.8e-22 76.8 25.5 2.6e-06 27.0 0.1 10.2 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMG46972.1 - 1.1e-19 68.9 11.2 0.00068 19.6 0.2 8.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMG46972.1 - 4.1e-18 64.5 1.3 0.14 13.1 0.0 9.6 6 2 3 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMG46972.1 - 9.7e-18 64.2 20.2 2.4e-07 31.0 0.1 8.8 6 3 1 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMG46972.1 - 2e-13 50.7 4.9 0.11 13.0 0.1 7.8 6 2 1 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMG46972.1 - 1.4e-11 43.9 9.8 0.053 13.9 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMG46972.1 - 1.4e-10 41.6 3.8 0.17 12.5 0.0 5.9 5 2 0 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EMG46972.1 - 2.2e-09 36.9 14.1 0.17 11.8 0.1 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 EMG46972.1 - 5.6e-09 35.4 9.4 0.64 10.2 0.1 7.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 EMG46972.1 - 6.7e-08 32.7 1.5 14 6.6 0.1 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMG46972.1 - 7.7e-08 31.9 14.4 0.00033 20.3 0.2 7.0 7 2 2 9 9 9 2 TPR repeat TPR_15 PF13429.6 EMG46972.1 - 3.3e-07 29.8 0.0 0.15 11.3 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EMG46972.1 - 7.4e-07 29.2 0.1 0.0016 18.5 0.0 4.5 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EMG46972.1 - 2.2e-06 27.3 0.1 0.0014 18.1 0.0 3.5 4 1 0 4 4 4 1 MalT-like TPR region Coatomer_E PF04733.14 EMG46972.1 - 0.0013 18.3 2.3 1.4 8.2 0.0 3.7 3 1 1 4 4 4 2 Coatomer epsilon subunit MIT PF04212.18 EMG46972.1 - 1.3 9.2 7.5 6.7 6.9 0.1 4.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain WD40 PF00400.32 EMG46973.1 - 2.5e-23 81.9 2.0 1.2e-06 29.1 0.2 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG46973.1 - 5.4e-11 42.7 1.4 0.018 15.3 0.1 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EMG46973.1 - 0.0002 21.4 0.9 3.6 7.7 0.4 4.1 1 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 EMG46973.1 - 0.00025 19.9 2.4 1.2 7.8 0.1 3.9 2 1 2 4 4 4 2 Nup133 N terminal like Nup160 PF11715.8 EMG46973.1 - 0.00061 18.6 0.1 0.059 12.0 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Utp8 PF10395.9 EMG46973.1 - 0.011 14.2 1.6 0.021 13.4 0.2 2.1 1 1 1 2 2 2 0 Utp8 family CRT10 PF08728.10 EMG46973.1 - 0.011 13.9 0.0 0.032 12.4 0.0 1.8 1 1 1 2 2 2 0 CRT10 PALB2_WD40 PF16756.5 EMG46973.1 - 0.036 13.0 2.4 1.2 8.0 0.1 3.1 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain AlaDh_PNT_N PF05222.15 EMG46974.1 - 2.9e-30 105.3 0.0 4.2e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EMG46974.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AA_permease PF00324.21 EMG46975.1 - 1.1e-50 172.7 10.6 1.2e-50 172.5 10.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG46975.1 - 2.7e-12 46.3 11.0 3.1e-12 46.0 11.0 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_Gp23 PF10669.9 EMG46975.1 - 0.0088 16.4 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) LapA_dom PF06305.11 EMG46975.1 - 8.1 6.3 8.8 2.7 7.9 0.4 3.1 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain AA_kinase PF00696.28 EMG46977.1 - 1.3e-43 149.3 0.0 2.3e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 EMG46977.1 - 1.1e-08 34.7 2.3 0.00035 20.3 0.2 3.1 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 EMG46977.1 - 2.6e-07 30.3 2.1 1.2e-05 25.0 0.3 2.6 2 0 0 2 2 2 2 ACT domain TetR_C_5 PF08360.11 EMG46977.1 - 0.05 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 QacR-like protein, C-terminal region BAR_2 PF10455.9 EMG46978.1 - 2.4e-61 207.4 9.5 3.9e-61 206.7 9.5 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EMG46978.1 - 2.1e-15 57.0 3.9 6.2e-15 55.5 3.9 1.7 1 1 0 1 1 1 1 BAR domain Csm2_III-A PF03750.13 EMG46978.1 - 0.0016 19.2 5.7 0.048 14.5 1.3 3.1 2 1 0 2 2 2 1 Csm2 Type III-A Arfaptin PF06456.13 EMG46978.1 - 0.004 16.8 4.6 0.049 13.2 0.3 2.9 1 1 1 3 3 3 1 Arfaptin-like domain DUF4945 PF16303.5 EMG46978.1 - 0.062 13.2 1.4 0.19 11.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) Frataxin_Cyay PF01491.16 EMG46978.1 - 0.065 13.3 1.9 0.74 9.9 0.0 3.2 4 0 0 4 4 4 0 Frataxin-like domain ACDC PF14733.6 EMG46978.1 - 0.089 13.1 1.3 1.4 9.2 0.0 2.6 2 1 0 2 2 2 0 AP2-coincident C-terminal Fib_alpha PF08702.10 EMG46978.1 - 0.51 10.5 11.1 0.6 10.3 3.3 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 EMG46978.1 - 1.4 9.3 15.8 1.8 9.0 1.0 4.0 1 1 3 4 4 4 0 Syntaxin-like protein WEMBL PF05701.11 EMG46978.1 - 1.9 7.1 8.2 1.1 7.9 0.5 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Laminin_II PF06009.12 EMG46978.1 - 2 8.5 11.2 2.4 8.2 0.2 3.7 3 1 1 4 4 4 0 Laminin Domain II LMBR1 PF04791.16 EMG46978.1 - 5.2 5.9 8.9 1.9e+02 0.7 8.9 2.1 1 1 0 1 1 1 0 LMBR1-like membrane protein Aminotran_1_2 PF00155.21 EMG46979.1 - 2.8e-24 86.0 0.0 4.2e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EMG46979.1 - 0.035 12.9 0.0 0.13 11.1 0.0 1.7 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase DNA_ligase_aden PF01653.18 EMG46979.1 - 0.17 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Tubulin PF00091.25 EMG46980.1 - 1e-73 247.8 0.2 2.5e-73 246.5 0.2 1.7 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EMG46980.1 - 3.9e-13 49.7 0.2 7.6e-13 48.7 0.2 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EMG46980.1 - 0.001 19.4 3.5 0.21 11.9 3.5 2.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EMG46980.1 - 0.0043 16.8 0.0 0.023 14.4 0.0 2.3 1 1 1 2 2 2 1 Tubulin domain Tubulin_2 PF13809.6 EMG46980.1 - 0.0057 15.9 0.0 0.016 14.4 0.0 1.7 2 0 0 2 2 2 1 Tubulin like DUF4451 PF14616.6 EMG46980.1 - 0.019 15.2 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Hrs_helical PF12210.8 EMG46980.1 - 0.053 14.1 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Sorting_nexin PF03700.13 EMG46980.1 - 0.6 10.7 2.9 2.5 8.7 0.1 3.1 3 1 1 4 4 4 0 Sorting nexin, N-terminal domain Cation_efflux PF01545.21 EMG46981.1 - 1.4e-06 28.2 14.2 4.5e-06 26.5 14.2 1.8 1 1 0 1 1 1 1 Cation efflux family SIS PF01380.22 EMG46982.1 - 2e-12 47.1 0.4 3.9e-12 46.2 0.4 1.5 1 0 0 1 1 1 1 SIS domain His_kinase PF06580.13 EMG46982.1 - 0.021 15.1 1.4 0.11 12.9 1.4 2.3 1 1 0 1 1 1 0 Histidine kinase NAD_binding_1 PF00175.21 EMG46983.1 - 5.3e-32 110.7 0.0 8.9e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EMG46983.1 - 2.1e-31 108.2 0.0 3.3e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EMG46983.1 - 2.9e-05 24.2 0.0 0.0025 18.0 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain Ofd1_CTDD PF10637.9 EMG46984.1 - 1.1e-95 319.9 0.2 1.4e-93 312.9 0.1 2.4 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EMG46984.1 - 8.7e-28 96.8 0.0 3.8e-27 94.8 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EMG46984.1 - 1.7e-14 54.5 0.0 2.9e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EMG46984.1 - 0.042 14.3 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Vps62 PF06101.11 EMG46986.1 - 1e-10 40.6 4.3 2.7e-10 39.2 4.3 1.5 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 AA_permease PF00324.21 EMG46987.1 - 7.3e-51 173.2 10.6 8.1e-51 173.1 10.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG46987.1 - 1.9e-12 46.8 11.0 2.2e-12 46.5 11.0 1.1 1 0 0 1 1 1 1 Amino acid permease LapA_dom PF06305.11 EMG46987.1 - 0.097 12.5 2.0 2.3 8.1 0.4 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3384 PF11864.8 EMG46989.1 - 3.1e-106 356.2 8.2 3.1e-106 356.2 8.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EMG46989.1 - 9.4e-46 155.7 4.1 1.2e-45 155.3 1.2 2.5 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.16 EMG46989.1 - 1.6e-23 83.4 2.8 1.5e-21 76.9 1.2 2.7 2 0 0 2 2 2 2 Tuberin Candida_ALS PF05792.13 EMG46990.1 - 1.9e-10 41.1 55.2 2.8e-10 40.6 16.6 4.0 4 0 0 4 4 4 3 Candida agglutinin-like (ALS) DUF4786 PF16027.5 EMG46992.1 - 0.038 14.6 2.7 0.042 14.4 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4786) DUF4637 PF15470.6 EMG46992.1 - 3.3 7.4 5.6 2.7 7.7 4.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) Vps5 PF09325.10 EMG46993.1 - 1.2e-80 270.5 17.0 1.2e-80 270.5 17.0 2.0 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EMG46993.1 - 3.8e-22 78.4 0.1 3.8e-22 78.4 0.1 2.4 2 0 0 2 2 2 1 PX domain Bromodomain PF00439.25 EMG46993.1 - 0.38 10.8 7.4 0.11 12.5 0.4 3.5 4 0 0 4 4 4 0 Bromodomain DUF4632 PF15451.6 EMG46993.1 - 0.73 9.9 3.5 2.1 8.5 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) AcylCoA_dehyd_C PF12186.8 EMG46993.1 - 2.6 8.2 6.2 11 6.2 0.8 3.6 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase C terminal Sec8_exocyst PF04048.14 EMG46993.1 - 4.1 7.3 17.1 2.6 7.9 7.9 3.6 2 1 2 4 4 4 0 Sec8 exocyst complex component specific domain gp45-slide_C PF09116.10 EMG46994.1 - 0.032 14.3 0.2 0.049 13.7 0.2 1.4 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal Usp PF00582.26 EMG46995.1 - 2.2e-21 76.8 0.0 3.2e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Fibrillarin PF01269.17 EMG46996.1 - 3.9e-105 350.0 0.0 4.8e-105 349.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EMG46996.1 - 0.00017 21.4 0.0 0.00035 20.3 0.0 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 EMG46996.1 - 0.0061 16.7 0.0 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 EMG46996.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UMP1 PF05348.11 EMG46997.1 - 6.2e-42 142.6 0.1 7.3e-42 142.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 GYF PF02213.16 EMG46998.1 - 1.1e-15 57.0 0.1 2.6e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EMG46998.1 - 0.002 17.9 0.3 0.012 15.4 0.0 2.5 3 0 0 3 3 3 1 GYF domain 2 ACT_7 PF13840.6 EMG46999.1 - 1.3e-30 105.0 0.6 1.3e-16 60.1 0.2 2.4 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 EMG46999.1 - 0.0013 18.5 1.5 11 5.9 0.2 3.5 3 0 0 3 3 3 3 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain AIM3 PF17096.5 EMG46999.1 - 9.3 7.3 8.1 1.1 10.2 2.5 2.0 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 IATP PF04568.12 EMG47000.1 - 0.77 10.2 4.7 2.3 8.7 0.5 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP UBA_4 PF14555.6 EMG47001.1 - 5.9e-12 45.2 0.3 1.4e-11 44.0 0.3 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EMG47001.1 - 5.5e-10 39.3 0.1 1.2e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 UBX domain NICE-3 PF07406.11 EMG47001.1 - 0.0088 16.1 2.4 0.018 15.0 2.4 1.4 1 0 0 1 1 1 1 NICE-3 protein Thioredoxin_7 PF13899.6 EMG47001.1 - 0.05 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like SF3a60_bindingd PF12108.8 EMG47001.1 - 0.22 11.5 1.9 2.2 8.3 0.1 2.7 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain RAMP4 PF06624.12 EMG47001.1 - 1.3 9.2 0.0 1.3 9.2 0.0 2.8 4 0 0 4 4 4 0 Ribosome associated membrane protein RAMP4 DUF4061 PF13270.6 EMG47001.1 - 8.5 6.8 10.1 1.1 9.7 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) DAO PF01266.24 EMG47002.1 - 6.7e-55 187.1 0.0 1.1e-54 186.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EMG47002.1 - 3.4e-40 136.8 0.0 1.2e-39 135.1 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EMG47002.1 - 2.5e-11 43.3 0.2 6.4e-11 42.0 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EMG47002.1 - 1.2e-07 31.5 1.5 6e-06 25.9 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EMG47002.1 - 0.0004 19.6 0.7 0.02 14.0 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EMG47002.1 - 0.0018 17.0 0.3 0.0037 16.0 0.3 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EMG47002.1 - 0.0021 17.4 1.2 0.015 14.6 1.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMG47002.1 - 0.019 14.2 2.4 0.084 12.1 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMG47002.1 - 0.028 14.7 1.3 0.13 12.5 0.6 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EMG47002.1 - 0.045 13.0 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EMG47002.1 - 0.046 13.0 1.6 0.18 11.0 1.6 1.9 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EMG47002.1 - 0.079 12.2 0.4 0.18 11.0 0.1 1.6 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 EMG47002.1 - 0.64 9.9 4.7 0.21 11.5 0.8 2.1 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.18 EMG47003.1 - 2.1e-05 24.5 12.7 4.2e-05 23.6 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec1 PF00995.23 EMG47004.1 - 3.6e-116 389.7 20.6 4.1e-116 389.5 20.6 1.0 1 0 0 1 1 1 1 Sec1 family KaiA PF07688.12 EMG47004.1 - 0.7 10.1 5.1 5.7 7.1 0.1 3.7 3 1 0 4 4 4 0 KaiA C-terminal domain TIP49 PF06068.13 EMG47005.1 - 3.4e-162 539.6 0.0 3.9e-162 539.4 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain AAA PF00004.29 EMG47005.1 - 4e-09 37.0 0.0 8.2e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMG47005.1 - 6.5e-08 32.5 0.1 4e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMG47005.1 - 0.00015 22.0 0.1 0.53 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EMG47005.1 - 0.0011 19.4 0.0 0.0082 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EMG47005.1 - 0.003 17.6 0.0 4 7.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EMG47005.1 - 0.0091 15.7 0.0 5.6 6.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 EMG47005.1 - 0.0094 16.0 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EMG47005.1 - 0.021 15.1 0.6 4 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMG47005.1 - 0.029 14.6 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMG47005.1 - 0.029 14.9 0.0 0.066 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMG47005.1 - 0.03 13.6 0.2 0.078 12.2 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin DnaB_C PF03796.15 EMG47005.1 - 0.039 13.3 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 EMG47005.1 - 0.053 12.9 0.2 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EMG47005.1 - 0.072 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EMG47005.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EMG47005.1 - 0.15 11.6 0.1 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EMG47006.1 - 7.7e-86 287.8 0.0 8.7e-86 287.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EMG47006.1 - 0.00013 21.8 0.0 0.00044 20.1 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 EMG47006.1 - 0.0016 17.5 0.0 0.0031 16.5 0.0 1.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_10 PF12846.7 EMG47006.1 - 0.0018 17.2 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain CbiA PF01656.23 EMG47006.1 - 0.0022 18.0 0.0 0.0027 17.8 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMG47006.1 - 0.0028 17.6 0.1 0.058 13.3 0.0 2.4 1 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EMG47006.1 - 0.0041 17.0 0.3 0.081 12.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 EMG47006.1 - 0.0043 16.8 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EMG47006.1 - 0.0051 16.9 0.0 0.017 15.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMG47006.1 - 0.0055 16.3 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Fer4_NifH PF00142.18 EMG47006.1 - 0.0061 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNA_helicase PF00910.22 EMG47006.1 - 0.008 16.5 0.0 0.025 14.9 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_5 PF07728.14 EMG47006.1 - 0.019 14.9 0.0 0.046 13.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 EMG47006.1 - 0.021 14.1 0.0 0.048 12.9 0.0 1.5 2 0 0 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.6 EMG47006.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EMG47006.1 - 0.028 14.8 0.4 0.069 13.5 0.1 1.8 1 1 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 EMG47006.1 - 0.029 14.4 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 EMG47006.1 - 0.039 14.5 0.2 0.094 13.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EMG47006.1 - 0.043 13.1 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 EMG47006.1 - 0.046 13.2 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 EMG47006.1 - 0.062 12.3 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 EMG47006.1 - 0.064 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArsA_ATPase PF02374.15 EMG47006.1 - 0.064 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA PF00004.29 EMG47006.1 - 0.065 13.7 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMG47006.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMG47006.1 - 0.08 13.3 0.0 0.2 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EMG47006.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 EMG47006.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 EMG47006.1 - 0.17 10.7 0.1 0.4 9.5 0.0 1.5 2 0 0 2 2 2 0 Papillomavirus helicase ABC_tran PF00005.27 EMG47006.1 - 0.18 12.4 0.0 0.43 11.1 0.0 1.7 2 0 0 2 2 1 0 ABC transporter AAA_30 PF13604.6 EMG47006.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EMG47006.1 - 0.23 11.2 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Cation_efflux PF01545.21 EMG47007.1 - 6.1e-41 140.4 9.5 6.1e-41 140.4 9.5 1.7 2 0 0 2 2 2 1 Cation efflux family DUF2946 PF11162.8 EMG47007.1 - 0.14 12.8 2.4 0.27 11.9 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Anoctamin PF04547.12 EMG47007.1 - 1.1 8.0 8.1 0.15 10.9 0.1 2.6 2 1 0 2 2 2 0 Calcium-activated chloride channel Cpn60_TCP1 PF00118.24 EMG47008.1 - 3.3e-168 560.3 1.0 3.8e-168 560.1 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_16 PF13191.6 EMG47008.1 - 0.032 14.6 0.1 0.067 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_M24 PF00557.24 EMG47011.1 - 6.3e-11 42.4 0.0 7.7e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Translin PF01997.16 EMG47012.1 - 1.5e-36 126.3 0.1 1.8e-36 126.0 0.1 1.1 1 0 0 1 1 1 1 Translin family NRDE-2 PF08424.10 EMG47013.1 - 1.7e-06 27.4 5.1 3.3e-06 26.5 0.3 3.1 2 2 1 3 3 3 1 NRDE-2, necessary for RNA interference Suf PF05843.14 EMG47013.1 - 5.1e-06 26.7 9.7 0.0015 18.6 0.1 3.3 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EMG47013.1 - 0.0067 17.2 0.0 5.7 8.0 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMG47013.1 - 0.32 11.5 4.8 58 4.4 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat ATP-synt_D PF01813.17 EMG47014.1 - 4.3e-67 225.7 7.4 6.6e-67 225.2 7.4 1.3 1 0 0 1 1 1 1 ATP synthase subunit D RICH PF05062.12 EMG47014.1 - 0.53 10.7 6.2 0.23 11.8 1.4 2.6 2 1 0 2 2 2 0 RICH domain adh_short_C2 PF13561.6 EMG47015.1 - 1.9e-63 214.1 0.2 2.4e-63 213.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMG47015.1 - 6.6e-41 139.9 0.4 8.6e-41 139.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG47015.1 - 1.6e-10 41.2 0.1 2.3e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMG47015.1 - 0.00053 19.5 0.0 0.0068 15.9 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 EMG47015.1 - 0.00082 19.2 0.6 0.0038 17.1 0.2 2.1 2 1 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Sacchrp_dh_NADP PF03435.18 EMG47015.1 - 0.04 14.2 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EMG47015.1 - 0.053 12.9 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Mrr_cat PF04471.12 EMG47015.1 - 0.076 13.1 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease adh_short_C2 PF13561.6 EMG47016.1 - 5.7e-64 215.9 0.1 7.1e-64 215.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMG47016.1 - 1.2e-38 132.5 0.1 1.4e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG47016.1 - 4e-10 39.9 0.1 5.6e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMG47016.1 - 0.0038 16.7 0.0 0.0069 15.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 EMG47016.1 - 0.032 14.0 0.1 0.078 12.8 0.1 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.17 EMG47016.1 - 0.062 12.4 0.1 0.72 8.9 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain FAD_binding_2 PF00890.24 EMG47017.1 - 4e-122 408.3 2.6 6.4e-122 407.6 2.6 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EMG47017.1 - 3.1e-44 150.0 0.2 4.7e-44 149.5 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 EMG47017.1 - 4.3e-05 22.9 0.3 0.033 13.4 0.1 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 EMG47017.1 - 0.00079 18.7 0.4 0.0019 17.5 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMG47017.1 - 0.0013 17.9 0.5 0.066 12.3 1.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EMG47017.1 - 0.059 12.6 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain DUF92 PF01940.16 EMG47018.1 - 0.13 11.7 0.3 3.3 7.1 0.1 2.0 2 0 0 2 2 2 0 Integral membrane protein DUF92 ERp29_N PF07912.13 EMG47019.1 - 0.024 14.8 0.2 0.033 14.3 0.2 1.2 1 0 0 1 1 1 0 ERp29, N-terminal domain Candida_ALS_N PF11766.8 EMG47020.1 - 6.1e-89 297.5 11.0 8.5e-89 297.1 11.0 1.2 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Candida_ALS PF05792.13 EMG47020.1 - 1.4e-06 28.7 49.6 1.8e-05 25.2 22.3 5.5 4 1 1 5 5 5 2 Candida agglutinin-like (ALS) Xan_ur_permease PF00860.20 EMG47021.1 - 1.5e-69 234.6 31.0 2.1e-69 234.1 31.0 1.1 1 0 0 1 1 1 1 Permease family DUF4029 PF13221.6 EMG47021.1 - 0.11 13.1 0.3 0.35 11.5 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4029) PEX11 PF05648.14 EMG47023.1 - 0.00011 21.7 0.2 0.013 15.0 0.0 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) SPT16 PF08644.11 EMG47024.1 - 1.7e-48 164.6 0.2 1.7e-48 164.6 0.2 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EMG47024.1 - 3.8e-45 153.6 4.1 4.2e-44 150.2 2.1 2.8 2 1 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EMG47024.1 - 2.6e-25 89.4 0.0 4.6e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EMG47024.1 - 7.4e-14 51.9 0.2 5.3e-13 49.2 0.1 2.5 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DNA_primase_lrg PF04104.14 EMG47025.1 - 4.6e-80 268.8 0.1 6.7e-80 268.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Pkinase PF00069.25 EMG47026.1 - 1.4e-69 234.4 0.0 1.4e-69 234.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG47026.1 - 2.7e-35 121.9 0.0 2.7e-35 121.9 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMG47026.1 - 9.9e-05 21.4 5.5 0.00018 20.6 5.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EMG47026.1 - 0.00035 20.0 0.4 0.00035 20.0 0.4 1.8 2 0 0 2 2 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EMG47026.1 - 0.014 14.4 0.1 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EMG47026.1 - 0.08 11.7 4.4 0.14 10.9 4.4 1.3 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EMG47026.1 - 0.081 12.8 0.1 0.081 12.8 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family EPL1 PF10513.9 EMG47026.1 - 0.1 13.0 2.8 0.18 12.2 2.8 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF2961 PF11175.8 EMG47026.1 - 0.19 11.3 0.7 0.38 10.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Ins145_P3_rec PF08709.11 EMG47026.1 - 0.37 9.9 3.7 0.59 9.3 3.7 1.3 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor FTA2 PF13095.6 EMG47026.1 - 0.5 9.9 0.0 0.5 9.9 0.0 2.9 1 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF2072 PF09845.9 EMG47026.1 - 0.53 10.6 2.5 0.95 9.7 2.5 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF4199 PF13858.6 EMG47026.1 - 0.96 9.8 3.6 1.6 9.1 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) TERB2 PF15101.6 EMG47026.1 - 1.2 9.2 10.5 1.7 8.6 10.5 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PepSY_TM PF03929.16 EMG47026.1 - 1.4 8.5 5.8 2.2 7.9 5.8 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Spore_III_AF PF09581.10 EMG47026.1 - 1.5 8.8 7.5 2.8 7.9 7.5 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Membralin PF09746.9 EMG47026.1 - 1.7 7.6 7.8 7.3 5.5 0.0 2.7 3 0 0 3 3 3 0 Tumour-associated protein TFIIA PF03153.13 EMG47026.1 - 2.5 8.0 21.9 3.2 7.7 21.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 EMG47026.1 - 3.3 7.0 12.5 4.8 6.5 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Roughex PF06020.11 EMG47026.1 - 3.7 6.6 7.8 5.8 5.9 7.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein eIF-3_zeta PF05091.12 EMG47026.1 - 6.3 5.7 12.2 9.3 5.1 12.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MPM1 PF17234.2 EMG47026.1 - 9 6.5 7.8 17 5.7 7.8 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF2406 PF10295.9 EMG47027.1 - 1.4e-27 96.1 1.0 2.9e-27 95.1 0.4 1.9 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) YL1_C PF08265.11 EMG47028.1 - 4.6e-13 48.7 0.2 8.9e-13 47.8 0.2 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Nuc_sug_transp PF04142.15 EMG47029.1 - 8.7e-10 38.3 1.4 1.7e-09 37.3 1.4 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EMG47029.1 - 3.9e-09 36.1 12.5 5.4e-09 35.7 12.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EMG47029.1 - 1.5e-06 28.4 24.4 0.0012 19.0 4.4 2.8 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EMG47029.1 - 0.00017 20.9 5.8 0.00033 20.0 5.8 1.8 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 EMG47029.1 - 0.05 12.9 12.2 0.5 9.7 12.2 1.9 1 1 0 1 1 1 0 Triose-phosphate Transporter family YfhO PF09586.10 EMG47029.1 - 0.14 10.3 6.7 0.14 10.4 0.1 2.1 1 1 0 2 2 2 0 Bacterial membrane protein YfhO SMP_LBD PF17047.5 EMG47029.1 - 1 8.8 4.3 14 5.1 0.9 2.2 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain Gram_pos_anchor PF00746.21 EMG47029.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.2 4 0 0 4 4 4 0 LPXTG cell wall anchor motif Mg_trans_NIPA PF05653.14 EMG47029.1 - 2.4 7.2 13.5 0.082 12.0 6.1 2.0 2 0 0 2 2 2 0 Magnesium transporter NIPA IspA PF04279.15 EMG47029.1 - 4.8 7.3 12.6 7.2 6.8 1.0 3.3 2 1 1 3 3 3 0 Intracellular septation protein A DUF4220 PF13968.6 EMG47029.1 - 5.9 6.2 7.1 4.6 6.6 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) DUF4131 PF13567.6 EMG47029.1 - 7.5 6.2 7.4 0.24 11.0 0.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) AFG1_ATPase PF03969.16 EMG47030.1 - 1.8e-78 264.0 0.0 2.7e-77 260.1 0.0 1.9 1 1 0 1 1 1 1 AFG1-like ATPase AAA_16 PF13191.6 EMG47030.1 - 3.7e-05 24.2 0.1 0.011 16.1 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EMG47030.1 - 0.0049 17.3 0.0 0.0098 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EMG47030.1 - 0.0058 16.7 0.0 0.028 14.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EMG47030.1 - 0.0074 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 EMG47030.1 - 0.0079 16.1 0.8 0.017 15.0 0.1 1.8 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.6 EMG47030.1 - 0.043 14.1 0.3 0.21 11.9 0.3 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EMG47030.1 - 0.056 12.8 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EMG47030.1 - 0.059 13.3 0.4 0.16 11.8 0.0 1.9 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EMG47030.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EMG47030.1 - 0.091 13.3 0.0 0.29 11.7 0.0 1.7 1 1 1 2 2 2 0 ABC transporter TsaE PF02367.17 EMG47030.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EMG47030.1 - 0.12 12.8 0.1 0.41 11.1 0.0 2.1 3 0 0 3 3 1 0 RNA helicase Rdx PF10262.9 EMG47031.1 - 1.7e-23 82.6 0.1 2.4e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 Rdx family Lin-8 PF03353.15 EMG47032.1 - 4.2 6.9 10.1 5.4 6.5 10.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SOG2 PF10428.9 EMG47032.1 - 5.2 6.2 27.4 6.6 5.8 27.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TPP_enzyme_N PF02776.18 EMG47034.1 - 9.7e-31 106.7 0.0 1.5e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMG47034.1 - 7.5e-29 100.2 0.0 5.2e-28 97.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EMG47034.1 - 4.2e-12 46.1 0.0 9e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.6 EMG47034.1 - 0.4 10.8 3.0 19 5.4 0.0 2.8 3 0 0 3 3 3 0 OCC1 family HLH PF00010.26 EMG47035.1 - 2.7e-12 46.4 4.4 6.6e-12 45.2 4.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SOBP PF15279.6 EMG47035.1 - 4.5 7.8 12.0 5.5 7.5 12.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DnaJ PF00226.31 EMG47036.1 - 1e-17 64.0 0.7 1e-17 64.0 0.7 2.1 3 0 0 3 3 3 1 DnaJ domain Fer4_NifH PF00142.18 EMG47036.1 - 0.12 11.8 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CarD_CdnL_TRCF PF02559.16 EMG47036.1 - 2.1 9.1 9.0 0.5 11.1 1.7 2.7 2 1 1 3 3 3 0 CarD-like/TRCF domain Fis1_TPR_C PF14853.6 EMG47036.1 - 2.4 8.3 9.7 2.2 8.4 1.6 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat LMBR1 PF04791.16 EMG47036.1 - 4.3 6.1 4.5 4.9 5.9 4.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DNA_topoisoIV PF00521.20 EMG47037.1 - 5.1e-126 421.0 0.1 1.1e-125 420.0 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EMG47037.1 - 5.1e-49 165.8 0.0 1.9e-48 163.9 0.0 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EMG47037.1 - 7.1e-27 94.0 2.8 1.5e-26 92.9 2.8 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EMG47037.1 - 3.3e-15 56.6 0.0 1.1e-14 54.8 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EMG47037.1 - 1.3e-06 28.6 0.0 5.9e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HBD PF18534.1 EMG47037.1 - 0.054 13.6 0.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Helical bundle domain LicD PF04991.13 EMG47039.1 - 4.1e-27 95.8 4.2 1.5e-24 87.4 1.0 5.8 3 2 1 4 4 4 2 LicD family Mem_trans PF03547.18 EMG47039.1 - 0.024 13.1 0.4 0.045 12.2 0.4 1.4 1 0 0 1 1 1 0 Membrane transport protein PD40 PF07676.12 EMG47040.1 - 0.033 14.1 0.2 2.4 8.2 0.3 3.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF1189 PF06691.11 EMG47040.1 - 0.29 10.7 6.2 6.2 6.3 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1189) GATA PF00320.27 EMG47041.1 - 4.1e-17 61.5 3.8 8.2e-17 60.5 3.8 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EMG47041.1 - 7.6e-12 44.8 1.9 1.9e-11 43.6 1.9 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF1139 PF06599.11 EMG47041.1 - 0.039 13.3 0.3 0.38 10.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1139) TF_Zn_Ribbon PF08271.12 EMG47041.1 - 0.11 12.0 0.3 0.28 10.8 0.3 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding LRR_9 PF14580.6 EMG47044.1 - 4.4e-19 68.6 1.1 4.4e-19 68.6 1.1 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 EMG47044.1 - 2.8e-09 36.6 6.9 2.8e-09 36.6 6.9 2.4 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EMG47044.1 - 1.2e-07 32.0 19.1 3.6e-05 24.1 3.8 3.8 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) Utp13 PF08625.11 EMG47044.1 - 0.073 13.0 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain EF-G-binding_N PF07299.11 EMG47044.1 - 0.091 13.3 1.6 0.23 12.0 1.6 1.7 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal LRR_5 PF13306.6 EMG47044.1 - 0.22 11.5 7.3 0.17 11.9 4.6 1.9 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) mRNA_cap_enzyme PF01331.19 EMG47045.1 - 1.6e-55 187.9 0.0 2.4e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EMG47045.1 - 1.7e-29 102.6 0.3 3.2e-29 101.7 0.3 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EMG47045.1 - 1.7e-06 27.8 0.0 0.035 13.7 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain NAD_binding_6 PF08030.12 EMG47046.1 - 1.7e-26 93.3 0.0 3.6e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMG47046.1 - 1.8e-26 92.4 0.0 3.9e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EMG47046.1 - 6.4e-23 81.2 13.8 6.4e-23 81.2 13.8 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EMG47047.1 - 5e-24 84.5 0.1 9.3e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EMG47047.1 - 1.2e-23 83.6 13.7 1.2e-23 83.6 13.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMG47047.1 - 6.4e-20 71.9 0.0 9.4e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4131 PF13567.6 EMG47047.1 - 2.2 7.9 5.3 3.2 7.4 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DnaJ-X PF14308.6 EMG47048.1 - 1.3e-61 207.7 12.0 1.3e-61 207.7 12.0 2.3 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 EMG47048.1 - 3e-25 88.1 2.3 6.2e-25 87.1 1.2 2.2 2 0 0 2 2 2 1 DnaJ domain Phage_int_SAM_4 PF13495.6 EMG47048.1 - 0.035 14.6 3.0 4.4 7.8 0.1 3.1 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain DUF3613 PF12266.8 EMG47048.1 - 0.17 11.7 3.3 0.19 11.5 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3613) O-antigen_lig PF13425.6 EMG47049.1 - 7.7 5.2 7.8 10 4.8 7.8 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4698 PF15769.5 EMG47049.1 - 8.4 5.3 21.9 11 4.9 21.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) BAH PF01426.18 EMG47050.1 - 2.3e-14 53.3 0.4 8.6e-14 51.4 0.1 2.3 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 EMG47050.1 - 7.1e-14 51.4 55.9 1.2e-07 31.5 11.1 6.2 6 0 0 6 6 6 3 PHD-finger zf-HC5HC2H_2 PF13832.6 EMG47050.1 - 9.2e-10 38.7 1.4 9.2e-10 38.7 1.4 4.7 4 0 0 4 4 4 2 PHD-zinc-finger like domain PHD_2 PF13831.6 EMG47050.1 - 1e-07 31.3 1.9 1e-07 31.3 1.9 4.6 6 0 0 6 6 6 2 PHD-finger zf-HC5HC2H PF13771.6 EMG47050.1 - 6.6e-07 29.5 1.8 6.6e-07 29.5 1.8 5.2 5 1 0 5 5 5 1 PHD-like zinc-binding domain Ins_allergen_rp PF06757.13 EMG47050.1 - 0.0046 17.0 0.3 0.014 15.4 0.1 1.9 2 0 0 2 2 2 1 Insect allergen related repeat, nitrile-specifier detoxification Myb_DNA-binding PF00249.31 EMG47050.1 - 0.026 14.7 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Acetyltransf_9 PF13527.7 EMG47052.1 - 1e-05 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMG47052.1 - 1.3e-05 25.5 0.1 3.3e-05 24.2 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMG47052.1 - 0.00067 19.9 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EMG47052.1 - 0.0031 17.4 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PT PF04886.12 EMG47053.1 - 4.7e-16 58.0 95.2 3.7e-08 32.8 20.7 6.5 3 2 2 5 5 5 4 PT repeat Zn_clus PF00172.18 EMG47054.1 - 1.6e-08 34.5 8.4 3.5e-08 33.4 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin_2 PF01920.20 EMG47055.1 - 1.1e-19 70.3 3.7 1.3e-19 70.1 3.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit HAUS2 PF15003.6 EMG47055.1 - 0.032 14.0 1.2 0.047 13.4 1.2 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 2 DUF5082 PF16888.5 EMG47055.1 - 0.071 13.4 2.0 0.24 11.7 2.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) TelA PF05816.11 EMG47055.1 - 0.072 12.1 3.8 0.084 11.9 3.8 1.0 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Spore_III_AB PF09548.10 EMG47055.1 - 0.088 12.9 0.2 0.12 12.5 0.2 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Nsp1_C PF05064.13 EMG47055.1 - 0.16 11.8 3.6 0.68 9.8 0.3 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region FlaC_arch PF05377.11 EMG47055.1 - 0.52 10.7 6.9 0.27 11.7 0.8 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) BLI1 PF17324.2 EMG47055.1 - 5.6 7.7 10.8 3.5 8.3 5.5 2.1 1 1 1 2 2 2 0 BLOC-1 interactor 1 HLH PF00010.26 EMG47056.1 - 9.3e-12 44.7 0.1 2.4e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A11 PF05061.13 EMG47056.1 - 0.077 12.3 2.0 0.2 10.9 2.0 1.6 1 0 0 1 1 1 0 Poxvirus A11 Protein GOLD_2 PF13897.6 EMG47056.1 - 9.7 6.7 7.8 9.2 6.8 0.1 3.1 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking Sec23_trunk PF04811.15 EMG47057.1 - 2.4e-70 236.9 0.0 3.6e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EMG47057.1 - 3.5e-33 114.2 1.1 6.7e-33 113.3 1.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EMG47057.1 - 2.5e-23 81.8 0.6 8.4e-23 80.2 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 EMG47057.1 - 1.9e-13 50.1 0.0 4.2e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 EMG47057.1 - 1.6e-10 40.9 8.6 3.4e-10 39.8 8.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 EMG47057.1 - 0.095 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 EMG47057.1 - 0.11 11.8 0.1 0.28 10.5 0.1 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Oxidored_FMN PF00724.20 EMG47058.1 - 3.8e-16 59.3 0.1 4.1e-16 59.2 0.1 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3638 PF12340.8 EMG47058.1 - 0.058 12.7 0.0 0.067 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) DUF5355 PF17306.2 EMG47059.1 - 1.5e-106 356.2 18.8 1.5e-106 356.2 18.8 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5355) Sec3-PIP2_bind PF15277.6 EMG47060.1 - 1.8e-15 56.8 0.3 5.6e-15 55.2 0.3 1.9 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.9 EMG47060.1 - 1.1e-05 24.0 4.7 1.1e-05 24.0 4.7 2.9 3 0 0 3 3 3 1 Exocyst complex component Sec3 3Beta_HSD PF01073.19 EMG47062.1 - 8.4e-85 284.2 0.0 1e-84 283.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMG47062.1 - 4.6e-32 111.4 0.0 6.1e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMG47062.1 - 1.6e-21 77.0 0.0 3.9e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EMG47062.1 - 6.5e-18 64.8 0.1 9.6e-17 61.0 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EMG47062.1 - 5.2e-12 46.0 0.0 7.6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EMG47062.1 - 6.6e-12 45.1 0.0 1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EMG47062.1 - 2.3e-08 33.5 0.0 4.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EMG47062.1 - 2.8e-05 23.8 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EMG47062.1 - 0.00031 20.7 0.0 0.0028 17.6 0.0 2.2 1 1 0 1 1 1 1 KR domain TAXi_C PF14541.6 EMG47062.1 - 0.074 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Piwi PF02171.17 EMG47063.1 - 4.6e-75 252.7 1.4 6.9e-75 252.1 1.4 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 EMG47063.1 - 8.9e-12 45.0 1.0 3e-11 43.3 0.1 2.1 2 0 0 2 2 2 1 PAZ domain ArgoN PF16486.5 EMG47063.1 - 3.2e-08 34.3 1.0 1.2e-07 32.4 1.0 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EMG47063.1 - 4.3e-06 26.3 0.1 9.3e-06 25.2 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EMG47063.1 - 0.0002 21.6 0.0 0.0011 19.3 0.0 2.3 2 0 0 2 2 2 1 Argonaute linker 2 domain adh_short PF00106.25 EMG47064.1 - 4.9e-44 150.1 0.1 7.3e-44 149.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG47064.1 - 1.6e-42 145.7 0.0 2.8e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG47064.1 - 6.1e-11 42.5 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Peptidase_M41 PF01434.18 EMG47065.1 - 7.1e-60 202.1 0.1 1.5e-59 201.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EMG47065.1 - 6.9e-42 143.0 0.0 4.9e-41 140.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMG47065.1 - 7.9e-07 28.8 0.0 1.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EMG47065.1 - 1.5e-05 25.4 0.4 0.00012 22.5 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EMG47065.1 - 4.1e-05 23.0 0.7 0.00015 21.1 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 EMG47065.1 - 0.00022 21.0 0.5 0.012 15.4 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMG47065.1 - 0.00064 20.0 1.0 0.13 12.5 0.1 3.2 2 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EMG47065.1 - 0.0011 19.0 0.1 0.0046 17.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EMG47065.1 - 0.018 15.0 0.3 0.47 10.5 0.0 3.1 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 EMG47065.1 - 0.02 14.6 0.1 0.055 13.2 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EMG47065.1 - 0.036 13.4 0.1 0.54 9.6 0.1 2.4 2 0 0 2 2 2 0 KaiC AAA_2 PF07724.14 EMG47065.1 - 0.048 13.8 0.9 0.17 12.0 0.0 2.5 3 1 0 3 3 2 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EMG47065.1 - 0.052 12.9 0.2 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EMG47065.1 - 0.054 13.7 0.1 0.16 12.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EMG47065.1 - 0.1 12.1 2.4 1.4 8.5 0.5 2.7 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 EMG47065.1 - 0.11 13.0 0.0 0.32 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-C4H2 PF10146.9 EMG47067.1 - 0.026 14.8 0.4 0.037 14.3 0.4 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein GAT PF03127.14 EMG47067.1 - 0.084 13.2 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 GAT domain TBPIP PF07106.13 EMG47068.1 - 2.2e-17 62.8 2.6 6.2e-17 61.3 2.6 1.8 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Glycos_trans_3N PF02885.17 EMG47068.1 - 0.011 15.5 0.1 5.9 6.8 0.0 2.7 2 1 0 2 2 2 0 Glycosyl transferase family, helical bundle domain TNF PF00229.18 EMG47068.1 - 0.029 14.3 0.9 0.053 13.5 0.6 1.7 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Het-C PF07217.11 EMG47068.1 - 0.11 11.1 0.1 0.11 11.1 0.1 2.0 1 1 1 2 2 2 0 Heterokaryon incompatibility protein Het-C Mnd1 PF03962.15 EMG47068.1 - 0.19 12.0 3.9 0.37 11.1 0.2 2.9 2 1 1 3 3 3 0 Mnd1 HTH domain DUF1664 PF07889.12 EMG47068.1 - 0.33 11.0 10.9 0.36 10.9 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 EMG47068.1 - 0.55 9.8 14.1 0.38 10.3 2.5 3.0 1 1 2 3 3 3 0 fzo-like conserved region TFIIE_beta PF02186.15 EMG47068.1 - 3.8 7.9 7.8 0.6 10.4 0.2 2.8 2 1 1 3 3 3 0 TFIIE beta subunit core domain RNA_polI_A14 PF08203.11 EMG47068.1 - 4.9 8.0 11.6 4.9 8.0 3.0 3.2 1 1 2 3 3 3 0 Yeast RNA polymerase I subunit RPA14 COMM_domain PF07258.14 EMG47068.1 - 5 7.3 10.1 0.11 12.6 0.7 3.0 4 0 0 4 4 4 0 COMM domain DUF2115 PF09888.9 EMG47068.1 - 5 7.6 12.1 2 8.9 2.9 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) SRCR_2 PF15494.6 EMG47068.1 - 5.3 7.6 6.1 1.5 9.4 0.2 2.6 2 1 1 3 3 3 0 Scavenger receptor cysteine-rich domain LRR_4 PF12799.7 EMG47069.1 - 5.6e-16 58.4 37.2 0.0013 19.1 1.0 6.6 4 2 0 5 5 5 4 Leucine Rich repeats (2 copies) CAP_GLY PF01302.25 EMG47069.1 - 1e-15 57.5 0.6 3.2e-15 55.9 0.1 2.0 2 1 0 2 2 2 1 CAP-Gly domain LRR_8 PF13855.6 EMG47069.1 - 2.6e-13 49.5 28.3 2.2e-07 30.5 0.6 5.6 2 2 4 6 6 6 5 Leucine rich repeat LRR_1 PF00560.33 EMG47069.1 - 0.006 17.0 27.2 5 8.1 0.0 8.6 6 1 1 7 7 7 1 Leucine Rich Repeat FNIP PF05725.12 EMG47069.1 - 0.014 15.6 1.5 0.48 10.6 0.0 4.0 3 1 0 3 3 3 0 FNIP Repeat LRR_6 PF13516.6 EMG47069.1 - 0.23 11.6 29.0 2.1 8.6 0.0 8.3 9 0 0 9 9 9 0 Leucine Rich repeat Helicase_C PF00271.31 EMG47070.1 - 1.7e-20 73.4 1.7 6.3e-19 68.4 1.0 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG47070.1 - 2.2e-20 73.4 0.0 2.2e-20 73.4 0.0 3.3 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMG47070.1 - 4.9e-18 65.5 0.0 3.6e-17 62.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMG47070.1 - 0.003 17.8 0.0 0.03 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Gal4_dimer PF03902.13 EMG47070.1 - 0.15 12.2 8.9 0.11 12.7 1.4 3.3 2 0 0 2 2 2 0 Gal4-like dimerisation domain GN3L_Grn1 PF08701.11 EMG47071.1 - 2.8e-22 78.6 17.1 8.3e-22 77.1 17.1 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EMG47071.1 - 9.5e-19 67.6 0.9 1.5e-14 54.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EMG47071.1 - 2.5e-10 40.1 0.1 4.6e-08 32.8 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMG47071.1 - 9.3e-07 28.9 0.4 2.2e-05 24.4 0.4 2.3 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 EMG47071.1 - 3e-05 23.7 0.1 0.061 12.8 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EMG47071.1 - 0.00013 22.1 8.7 0.31 11.1 0.0 4.0 2 2 1 3 3 3 2 Dynamin family Roc PF08477.13 EMG47071.1 - 0.00084 19.6 0.1 0.24 11.6 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EMG47071.1 - 0.0064 15.8 0.1 0.045 13.1 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_18 PF13238.6 EMG47071.1 - 0.01 16.4 2.1 0.012 16.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 EMG47071.1 - 0.019 14.0 0.0 0.044 12.8 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 EMG47071.1 - 0.022 14.3 0.2 0.78 9.3 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EMG47071.1 - 0.053 13.9 4.0 0.43 11.0 0.0 3.1 2 2 0 2 2 2 0 AAA ATPase domain RRN3 PF05327.11 EMG47071.1 - 0.28 9.7 8.0 0.4 9.2 8.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HNF-1_N PF04814.13 EMG47071.1 - 0.73 10.4 7.8 2 9.0 4.0 2.3 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus BUD22 PF09073.10 EMG47071.1 - 2.4 7.4 26.6 4.7 6.4 26.6 1.4 1 0 0 1 1 1 0 BUD22 STATa_Ig PF18214.1 EMG47072.1 - 0.1 12.6 2.8 0.075 13.0 0.7 1.8 2 0 0 2 2 2 0 STATa Immunoglobulin-like domain GDA1_CD39 PF01150.17 EMG47073.1 - 2.1e-123 412.2 4.2 2.8e-123 411.7 4.2 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SHR-BD PF06650.12 EMG47074.1 - 2.2e-92 309.3 2.8 2.3e-88 296.1 0.7 2.7 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 EMG47074.1 - 6.8e-86 287.5 6.6 6.5e-82 274.5 0.6 4.8 4 1 1 5 5 5 2 Repeating coiled region of VPS13 VPS13 PF16908.5 EMG47074.1 - 3e-78 262.9 8.7 3.2e-75 253.0 2.9 3.7 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EMG47074.1 - 1.3e-72 243.3 7.1 6.9e-68 227.9 0.6 3.2 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EMG47074.1 - 6.6e-41 139.1 1.0 2.7e-40 137.1 1.0 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EMG47074.1 - 8.8e-05 22.8 0.0 0.00023 21.4 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Formyl_trans_N PF00551.19 EMG47075.1 - 4.1e-33 114.6 0.0 6e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EMG47075.1 - 0.00029 21.0 0.0 0.00055 20.1 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Rrn6 PF10214.9 EMG47076.1 - 7.1e-51 173.7 44.8 2.1e-49 168.8 3.2 3.3 2 1 0 2 2 2 1 RNA polymerase I-specific transcription-initiation factor HPIH PF13323.6 EMG47076.1 - 0.043 13.7 4.0 0.13 12.1 4.0 1.8 1 0 0 1 1 1 0 N-terminal domain with HPIH motif Ead_Ea22 PF13935.6 EMG47076.1 - 0.049 14.3 0.2 0.71 10.5 0.0 2.3 2 0 0 2 2 2 0 Ead/Ea22-like protein 7TMR-HDED PF07697.11 EMG47076.1 - 4.4 7.4 9.8 0.29 11.2 0.7 2.5 2 0 0 2 2 2 0 7TM-HD extracellular Glyco_hydro_63 PF03200.16 EMG47077.1 - 3.6e-180 599.9 2.8 3.1e-179 596.8 2.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EMG47077.1 - 9.7e-79 264.6 0.0 2e-78 263.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EMG47077.1 - 3e-05 23.1 1.2 4.9e-05 22.3 1.2 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 EMG47077.1 - 0.011 14.7 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Bac_rhamnosid6H PF17389.2 EMG47077.1 - 0.1 11.8 0.5 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trp_syntA PF00290.20 EMG47078.1 - 9.6e-95 316.3 0.2 1.4e-94 315.8 0.2 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EMG47078.1 - 2.8e-46 158.3 0.5 2.8e-46 158.3 0.5 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ELFV_dehydrog PF00208.21 EMG47079.1 - 1e-85 287.4 5.7 1.2e-85 287.1 5.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EMG47079.1 - 5.8e-50 168.5 0.0 1.2e-49 167.5 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain GATase_4 PF13230.6 EMG47079.1 - 0.096 11.6 0.0 9.3 5.1 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Mcp5_PH PF12814.7 EMG47080.1 - 2.9e-44 150.1 0.3 2.9e-44 150.1 0.3 2.6 3 0 0 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EMG47080.1 - 0.00071 20.1 0.0 0.0025 18.3 0.0 2.1 1 0 0 1 1 1 1 PH domain YqzH PF14164.6 EMG47080.1 - 10 6.3 10.7 12 6.1 0.4 5.8 4 1 0 5 5 5 0 YqzH-like protein Nodulin-like PF06813.13 EMG47081.1 - 4.5e-15 55.8 10.4 4.5e-15 55.8 10.4 2.8 3 1 0 3 3 3 2 Nodulin-like MFS_1 PF07690.16 EMG47081.1 - 1.9e-12 46.8 33.7 1.9e-12 46.8 33.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cornichon PF03311.14 EMG47081.1 - 0.02 15.2 1.1 0.098 13.0 0.2 2.7 2 0 0 2 2 2 0 Cornichon protein Pkr1 PF08636.10 EMG47081.1 - 1.4 9.1 6.2 1.7 8.8 0.2 3.3 3 0 0 3 3 3 0 ER protein Pkr1 EF-hand_1 PF00036.32 EMG47082.1 - 8e-38 125.2 8.6 6.2e-09 34.8 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EMG47082.1 - 1.8e-32 111.6 1.5 1.5e-15 57.3 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EMG47082.1 - 4.6e-28 95.4 8.8 7.5e-08 31.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EMG47082.1 - 9.3e-28 93.8 6.3 1.2e-08 34.2 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EMG47082.1 - 3.6e-26 90.8 7.5 4.8e-12 45.5 0.1 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EMG47082.1 - 1.1e-14 54.4 0.1 4.1e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EMG47082.1 - 1.7e-10 41.2 0.1 0.00019 21.7 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EMG47082.1 - 7.3e-10 38.7 1.9 7.8e-05 22.6 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 EMG47082.1 - 3.8e-07 30.0 0.0 0.036 14.1 0.0 3.4 4 0 0 4 4 4 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 EMG47082.1 - 5.6e-07 29.7 7.5 0.0062 16.7 1.5 3.3 1 1 2 3 3 3 3 Dockerin type I domain TerB PF05099.13 EMG47082.1 - 5.3e-06 26.5 0.3 0.0094 15.9 0.1 2.3 2 0 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_11 PF08976.11 EMG47082.1 - 2.5e-05 25.1 0.1 0.025 15.4 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 EMG47082.1 - 0.00064 19.7 0.3 0.35 10.8 0.0 3.2 1 1 2 3 3 3 1 Caleosin related protein EF-hand_14 PF17959.1 EMG47082.1 - 0.00076 19.8 0.2 0.52 10.7 0.0 2.5 2 2 0 2 2 2 1 EF-hand domain Poly_export PF02563.16 EMG47082.1 - 0.002 18.3 0.0 0.02 15.1 0.0 2.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein DUF3349 PF11829.8 EMG47082.1 - 0.0022 18.8 0.6 4.5 8.1 0.2 2.8 1 1 0 2 2 2 2 Protein of unknown function (DUF3349) EF-hand_10 PF14788.6 EMG47082.1 - 0.017 14.9 1.7 0.042 13.7 0.1 2.4 3 1 0 3 3 3 0 EF hand DUF4497 PF14924.6 EMG47082.1 - 0.026 15.0 0.0 4.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Spore_III_AB PF09548.10 EMG47082.1 - 0.046 13.8 0.2 0.098 12.8 0.2 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF5580 PF17743.1 EMG47082.1 - 0.057 12.0 0.0 0.058 11.9 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) RNA_pol_Rpb4 PF03874.16 EMG47082.1 - 0.083 13.2 0.7 14 6.1 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 CSN8_PSD8_EIF3K PF10075.9 EMG47083.1 - 0.00079 19.4 1.0 0.0015 18.5 1.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family hGDE_central PF14702.6 EMG47083.1 - 0.024 14.3 0.1 0.047 13.3 0.1 1.5 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme ESSS PF10183.9 EMG47083.1 - 0.032 14.4 0.3 12 6.2 0.3 2.4 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glycos_transf_1 PF00534.20 EMG47084.1 - 1.7e-11 43.9 0.0 2.7e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMG47084.1 - 5.6e-10 39.8 0.0 1e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMG47084.1 - 1.3e-05 25.2 0.0 2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DUF1972 PF09314.11 EMG47084.1 - 0.11 12.0 0.2 0.53 9.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1972) Hist_deacetyl PF00850.19 EMG47085.1 - 3.9e-70 236.8 0.1 4.8e-70 236.5 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain IMS PF00817.20 EMG47086.1 - 2.6e-36 124.9 0.0 6.9e-36 123.5 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 EMG47086.1 - 4.4e-15 55.9 0.2 1.4e-14 54.2 0.2 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 EMG47086.1 - 5.4e-12 46.5 0.0 3.6e-11 43.8 0.0 2.4 2 1 1 3 3 3 1 impB/mucB/samB family C-terminal domain LIG3_BRCT PF16759.5 EMG47086.1 - 1e-07 32.2 3.0 5e-06 26.7 0.1 3.2 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain REV1_C PF16727.5 EMG47086.1 - 2.9e-07 30.8 0.1 1.2e-06 28.8 0.1 2.1 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain BRCT PF00533.26 EMG47086.1 - 6.5e-06 26.4 1.6 1.1e-05 25.7 0.2 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EMG47086.1 - 0.00042 20.2 0.2 0.0009 19.1 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 EMG47086.1 - 0.001 19.3 0.0 0.028 14.8 0.0 3.1 3 0 0 3 3 2 1 IMS family HHH motif mCpol PF18182.1 EMG47086.1 - 0.057 13.8 0.1 0.31 11.4 0.0 2.3 2 0 0 2 2 2 0 minimal CRISPR polymerase domain RTT107_BRCT_5 PF16770.5 EMG47086.1 - 0.096 12.6 0.0 0.34 10.8 0.0 2.0 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain SAM_3 PF18016.1 EMG47086.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1805 PF08827.11 EMG47086.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DSPc PF00782.20 EMG47088.1 - 8.2e-11 41.8 1.0 2.4e-09 37.1 0.2 2.8 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain NIF3 PF01784.18 EMG47089.1 - 8.5e-76 254.8 0.1 1.1e-75 254.5 0.1 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Kelch_4 PF13418.6 EMG47090.1 - 5.5e-15 55.1 2.1 1.2e-05 25.2 0.0 4.5 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EMG47090.1 - 7.2e-13 48.2 5.7 0.00011 22.1 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 EMG47090.1 - 3.8e-12 46.0 6.5 5.7e-05 23.2 0.1 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EMG47090.1 - 8.2e-12 44.5 3.9 1.6e-06 27.5 0.1 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EMG47090.1 - 5e-09 35.8 3.3 0.031 14.3 0.2 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EMG47090.1 - 9.9e-09 35.3 1.7 0.0032 17.7 0.0 4.1 5 0 0 5 5 5 2 Galactose oxidase, central domain BTB PF00651.31 EMG47090.1 - 0.042 14.1 0.0 0.54 10.5 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain TMEM171 PF15471.6 EMG47090.1 - 0.21 10.6 3.2 0.37 9.7 3.2 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Phosphodiest PF01663.22 EMG47091.1 - 1.4e-87 294.6 0.8 1.9e-87 294.2 0.8 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase RNase_PH PF01138.21 EMG47092.1 - 2.5e-15 57.2 0.0 3.8e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EMG47092.1 - 1.1e-08 35.0 0.1 4e-08 33.2 0.0 2.0 2 1 0 2 2 2 1 3' exoribonuclease family, domain 2 Gly_transf_sug PF04488.15 EMG47093.1 - 8e-22 77.7 0.1 2.2e-21 76.3 0.1 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Hyphal_reg_CWP PF11765.8 EMG47094.1 - 8.6e-114 379.9 0.4 1.2e-113 379.4 0.4 1.2 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal FAD_binding_1 PF00667.20 EMG47095.1 - 1.2e-69 234.3 0.0 2.4e-69 233.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EMG47095.1 - 1.7e-08 35.1 0.0 5.8e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Propeptide_C25 PF08126.11 EMG47095.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Propeptide_C25 PFOR_II PF17147.4 EMG47095.1 - 0.049 14.0 0.1 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II FAD_binding_6 PF00970.24 EMG47095.1 - 0.065 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Hyphal_reg_CWP PF11765.8 EMG47096.1 - 2.6e-128 427.6 3.6 2.6e-128 427.6 3.6 1.9 2 1 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal Reg_prop PF07494.11 EMG47096.1 - 0.083 13.2 1.9 2.2 8.8 0.3 3.3 2 0 0 2 2 2 0 Two component regulator propeller Rhomboid_SP PF12595.8 EMG47096.1 - 1.9 7.8 5.1 3.3 7.0 5.1 1.4 1 0 0 1 1 1 0 Rhomboid serine protease RNase_H2-Ydr279 PF09468.10 EMG47097.1 - 3.9e-14 53.1 1.0 3.9e-14 53.1 1.0 1.7 1 1 1 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EMG47097.1 - 1.5e-11 44.4 0.5 3e-11 43.4 0.5 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Band_7 PF01145.25 EMG47098.1 - 8.2e-20 71.6 0.0 1.1e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Acyltransferase PF01553.21 EMG47101.1 - 5.9e-11 42.1 0.0 3.4e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase LPD5 PF18799.1 EMG47101.1 - 0.12 12.8 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 Rrp15p PF07890.12 EMG47102.1 - 4.1e-33 114.6 12.0 4.1e-33 114.6 12.0 2.3 2 1 0 2 2 2 1 Rrp15p Kinesin PF00225.23 EMG47103.1 - 2.8e-102 342.1 4.9 2.8e-102 342.1 4.9 2.1 1 1 1 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EMG47103.1 - 6.5e-52 175.4 0.1 6.5e-52 175.4 0.1 2.7 2 0 0 2 2 2 1 Microtubule binding DAPDH_C PF16654.5 EMG47103.1 - 0.016 15.1 2.8 0.047 13.5 2.8 2.0 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain VirE PF05272.11 EMG47103.1 - 0.026 14.2 2.7 0.058 13.1 2.7 1.7 1 0 0 1 1 1 0 Virulence-associated protein E YtxH PF12732.7 EMG47103.1 - 8.9 6.9 12.1 2.5e+03 -0.9 10.1 4.0 2 1 0 2 2 2 0 YtxH-like protein PPR_2 PF13041.6 EMG47104.1 - 0.0017 18.5 0.9 13 6.1 0.0 4.5 5 0 0 5 5 5 2 PPR repeat family PPR_long PF17177.4 EMG47104.1 - 0.0069 15.8 0.1 1.6 8.1 0.0 2.8 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 EMG47104.1 - 0.093 12.6 0.9 5.9 6.8 0.1 3.9 3 1 1 4 4 4 0 Mitochondrial ATPase expression PPR PF01535.20 EMG47104.1 - 0.17 12.2 6.5 10 6.6 0.0 5.1 6 0 0 6 6 6 0 PPR repeat Pescadillo_N PF06732.11 EMG47105.1 - 1.3e-118 395.5 3.1 1.3e-118 395.5 3.1 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EMG47105.1 - 2.9e-11 43.6 0.1 1e-10 41.9 0.1 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EMG47105.1 - 0.0011 19.3 0.0 0.0011 19.3 0.0 3.1 4 1 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EMG47105.1 - 0.0051 17.1 0.0 0.028 14.7 0.0 2.3 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain ATP-synt_S1 PF05827.12 EMG47106.1 - 1.2e-05 25.1 0.1 2.8e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) ERG4_ERG24 PF01222.17 EMG47107.1 - 2.3e-110 369.3 2.8 5.8e-94 315.3 1.7 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EMG47107.1 - 0.00011 21.8 0.3 0.00015 21.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DDE_Tnp_Tn3 PF01526.17 EMG47107.1 - 0.19 10.5 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Tn3 transposase DDE domain AMPK1_CBM PF16561.5 EMG47108.1 - 1.7e-30 105.1 0.2 4.8e-30 103.6 0.2 1.8 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EMG47108.1 - 2.9e-27 94.7 3.9 2.9e-27 94.7 3.9 2.3 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Roughex PF06020.11 EMG47108.1 - 3.8 6.5 8.1 6.5 5.8 8.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Med18 PF09637.10 EMG47110.1 - 1.6e-103 345.9 4.1 1.9e-103 345.7 4.1 1.0 1 0 0 1 1 1 1 Med18 protein Serglycin PF04360.12 EMG47111.1 - 0.0016 18.4 1.0 0.0016 18.4 1.0 2.4 2 0 0 2 2 2 1 Serglycin AT_hook PF02178.19 EMG47111.1 - 2.9 8.1 7.5 11 6.3 7.5 2.0 1 0 0 1 1 1 0 AT hook motif Ribosomal_L3 PF00297.22 EMG47112.1 - 7.2e-188 624.1 12.3 8.2e-188 623.9 12.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 WD40 PF00400.32 EMG47113.1 - 3.7e-16 59.2 2.0 0.00012 22.8 0.2 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG47113.1 - 5.5e-08 33.0 0.0 0.4 11.0 0.0 4.3 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EMG47113.1 - 7.3e-06 26.0 0.1 0.85 9.7 0.0 4.8 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 EMG47113.1 - 0.094 12.0 0.6 3.3 7.0 0.5 3.1 2 1 2 4 4 4 0 PTHB1 N-terminus Y_phosphatase2 PF03162.13 EMG47114.1 - 7.7e-43 145.9 0.3 1.2e-41 142.0 0.3 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EMG47114.1 - 3.9e-06 27.0 0.0 4.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EMG47114.1 - 0.0031 17.1 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EMG47114.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain SGS PF05002.15 EMG47115.1 - 5.9e-23 80.8 2.7 2.1e-22 79.0 2.7 2.0 1 0 0 1 1 1 1 SGS domain HAGH_C PF16123.5 EMG47115.1 - 4.4e-18 65.6 0.5 1.9e-17 63.5 0.1 2.4 2 0 0 2 2 1 1 Hydroxyacylglutathione hydrolase C-terminus CS PF04969.16 EMG47115.1 - 1e-17 64.9 0.7 1e-17 64.9 0.7 2.1 2 0 0 2 2 1 1 CS domain MFS_1 PF07690.16 EMG47115.1 - 2.1e-17 63.1 53.0 3.7e-16 59.0 23.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.27 EMG47115.1 - 2.7e-10 40.6 1.9 5.6e-10 39.5 1.9 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_2 PF07719.17 EMG47115.1 - 2.1e-07 30.5 3.8 0.0037 17.3 0.6 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMG47115.1 - 1.2e-06 28.1 5.4 0.00021 20.9 0.5 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 EMG47115.1 - 2.7e-06 27.6 0.1 5.4e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMG47115.1 - 2.3e-05 24.0 7.6 0.016 15.0 1.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMG47115.1 - 0.00059 19.9 9.2 0.061 13.6 2.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMG47115.1 - 0.008 16.7 0.4 0.02 15.4 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMG47115.1 - 0.021 15.5 0.0 2.3 8.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMG47115.1 - 0.024 15.2 2.7 4 8.3 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 EMG47115.1 - 0.031 13.8 0.7 0.11 11.9 0.7 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain TPR_17 PF13431.6 EMG47115.1 - 0.15 12.5 2.5 0.47 11.0 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat FMN_red PF03358.15 EMG47116.1 - 1.6e-07 31.2 0.0 2.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMG47116.1 - 0.00012 21.9 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold zf-CHCC PF10276.9 EMG47117.1 - 1.4e-15 57.0 0.3 2.7e-15 56.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 EMG47117.1 - 0.033 13.9 1.0 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 Zinc Finger domain LrgB PF04172.16 EMG47118.1 - 2e-51 174.5 6.7 2e-51 174.5 6.7 1.6 2 0 0 2 2 2 1 LrgB-like family LRR_8 PF13855.6 EMG47119.1 - 4.7e-14 51.9 31.7 7.2e-05 22.5 0.0 6.7 5 2 1 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 EMG47119.1 - 1.3e-12 47.7 43.7 0.0006 20.2 4.9 8.4 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMG47119.1 - 0.00039 20.2 23.1 18 5.7 0.2 8.8 9 0 0 9 9 9 2 Leucine Rich repeat F-box-like_2 PF13013.6 EMG47119.1 - 0.089 12.8 0.2 13 5.8 0.0 3.0 3 0 0 3 3 3 0 F-box-like domain LRR_3 PF07725.12 EMG47119.1 - 1.4 8.9 17.3 4.7 7.2 0.1 5.5 4 0 0 4 4 4 0 Leucine Rich Repeat SQS_PSY PF00494.19 EMG47120.1 - 3.1e-43 148.2 0.0 3.9e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase MINDY_DUB PF04424.13 EMG47121.1 - 1.1e-15 57.6 2.4 1.4e-15 57.3 0.6 2.1 1 1 1 2 2 2 1 MINDY deubiquitinase Paf1 PF03985.13 EMG47122.1 - 1.9e-74 251.2 8.3 2.4e-74 250.9 8.3 1.1 1 0 0 1 1 1 1 Paf1 DNA_pol_B_thumb PF14791.6 EMG47122.1 - 0.056 13.6 0.1 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 DNA polymerase beta thumb Flocculin_t3 PF13928.6 EMG47123.1 - 1.1e-20 73.8 44.0 3.5e-15 56.2 17.2 7.0 4 3 1 5 5 5 2 Flocculin type 3 repeat SDA1 PF05285.12 EMG47123.1 - 7.8 5.8 17.5 12 5.2 17.5 1.2 1 0 0 1 1 1 0 SDA1 Gtr1_RagA PF04670.12 EMG47124.1 - 3.2e-93 311.4 3.6 4.5e-93 310.9 3.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EMG47124.1 - 3.8e-08 33.6 0.3 1.2e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG47124.1 - 1e-07 31.6 0.1 1e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 EMG47124.1 - 4.8e-07 29.5 0.2 9.5e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EMG47124.1 - 7.4e-07 29.2 0.0 1.9e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.13 EMG47124.1 - 0.02 14.1 0.1 0.04 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EMG47124.1 - 0.025 15.1 0.3 0.025 15.1 0.3 2.0 2 2 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 EMG47124.1 - 0.045 13.7 2.3 1.2 9.0 0.2 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EMG47124.1 - 0.057 13.2 1.1 0.19 11.5 1.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EMG47124.1 - 0.79 10.0 2.6 3.4 7.9 0.7 2.6 2 1 0 2 2 2 0 AAA domain Pilosulin PF17499.2 EMG47125.1 - 0.039 14.1 7.7 18 5.6 0.3 4.1 1 1 2 3 3 3 0 Ant venom peptides CUE PF02845.16 EMG47126.1 - 4.9e-05 23.0 0.1 9.4e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 CUE domain Adap_comp_sub PF00928.21 EMG47127.1 - 3.4e-75 252.8 0.8 4.5e-75 252.4 0.8 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMG47127.1 - 0.0014 18.5 0.6 0.0029 17.5 0.6 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Flocculin_t3 PF13928.6 EMG47128.1 - 2.9e-34 117.3 72.4 1.2e-14 54.5 18.2 7.4 6 1 0 6 6 6 3 Flocculin type 3 repeat Flocculin_t3 PF13928.6 EMG47129.1 - 6e-54 180.3 286.8 1.2e-13 51.3 16.9 15.3 14 2 2 16 16 16 9 Flocculin type 3 repeat Anp1 PF03452.14 EMG47130.1 - 8.5e-111 369.6 0.0 1.2e-110 369.1 0.0 1.2 1 0 0 1 1 1 1 Anp1 SMC_N PF02463.19 EMG47131.1 - 4e-61 206.2 39.5 1e-57 195.1 39.5 4.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EMG47131.1 - 1.5e-18 67.2 0.2 7.7e-18 64.9 0.2 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EMG47131.1 - 1.5e-07 32.1 40.1 1.5e-07 32.1 40.1 6.9 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 EMG47131.1 - 2.5e-07 30.8 3.6 4.2e-05 23.5 0.2 3.7 4 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMG47131.1 - 5.7e-05 22.8 0.1 0.00015 21.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 EMG47131.1 - 0.0001 20.0 14.1 0.0001 20.0 14.1 4.1 2 2 2 4 4 4 1 Protein of unknown function (DUF3584) AAA_15 PF13175.6 EMG47131.1 - 0.0023 17.7 32.1 0.0023 17.7 32.1 4.5 2 2 2 4 4 4 2 AAA ATPase domain Seryl_tRNA_N PF02403.22 EMG47131.1 - 0.013 15.7 11.6 0.013 15.7 11.6 9.7 5 3 5 10 10 10 0 Seryl-tRNA synthetase N-terminal domain Gly-zipper_Omp PF13488.6 EMG47132.1 - 0.0022 18.0 16.7 1.4 9.0 16.7 2.4 1 1 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.15 EMG47132.1 - 1 9.3 12.1 46 4.0 12.1 2.3 1 1 0 1 1 1 0 Glycine zipper 2TM domain Transgly_assoc PF04226.13 EMG47132.1 - 1.9 8.8 17.8 3.9e+03 -1.8 17.8 2.9 1 1 0 1 1 1 0 Transglycosylase associated protein FMN_red PF03358.15 EMG47133.1 - 8.1e-11 41.9 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMG47133.1 - 2.7e-05 24.0 0.0 3.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Lectin_leg-like PF03388.13 EMG47135.1 - 3.2e-49 167.4 0.0 4.3e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EMG47135.1 - 1.4e-08 35.0 0.1 2.3e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Bacterial lectin Syntaxin_2 PF14523.6 EMG47135.1 - 0.041 14.2 2.8 0.1 13.0 2.8 1.6 1 0 0 1 1 1 0 Syntaxin-like protein SecY PF00344.20 EMG47135.1 - 0.099 11.9 1.6 0.46 9.7 0.2 2.0 2 0 0 2 2 2 0 SecY translocase AAA_11 PF13086.6 EMG47135.1 - 0.13 12.0 0.9 0.23 11.2 0.9 1.3 1 0 0 1 1 1 0 AAA domain Pho86 PF11124.8 EMG47136.1 - 4.4e-111 371.0 1.0 5e-111 370.8 1.0 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 FMO-like PF00743.19 EMG47137.1 - 1.4e-31 109.5 4.8 2.7e-13 49.2 0.1 3.0 1 1 2 3 3 3 3 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EMG47137.1 - 3.6e-11 42.8 0.7 1.9e-06 27.3 0.1 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMG47137.1 - 1.8e-09 37.3 3.4 1.8e-09 37.3 3.4 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMG47137.1 - 3.3e-08 33.7 0.0 1.9e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMG47137.1 - 6.4e-07 28.9 0.2 0.00045 19.6 0.0 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMG47137.1 - 0.00051 20.2 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMG47137.1 - 0.001 18.7 0.5 0.21 11.2 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase baeRF_family5 PF18846.1 EMG47137.1 - 0.0033 17.6 0.8 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 Bacterial archaeo-eukaryotic release factor family 5 Thi4 PF01946.17 EMG47137.1 - 0.06 12.6 0.2 6.5 5.9 0.1 2.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EMG47137.1 - 0.066 13.8 0.8 11 6.6 0.1 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EMG47137.1 - 0.095 12.8 0.5 3 7.9 0.1 2.5 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SLAC1 PF03595.17 EMG47138.1 - 1.6e-64 218.3 38.7 2e-64 217.9 38.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4064 PF13273.6 EMG47138.1 - 0.019 15.2 12.9 2.7 8.3 0.2 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) Abhydro_lipase PF04083.16 EMG47140.1 - 1.4e-20 72.6 0.0 2.8e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EMG47140.1 - 3.9e-08 33.3 0.6 1.6e-05 24.7 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG47140.1 - 0.00042 19.7 0.0 0.025 13.8 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 DUF3089 PF11288.8 EMG47140.1 - 0.037 13.6 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) IU_nuc_hydro PF01156.19 EMG47141.1 - 5e-74 249.6 0.0 6e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Gin PF10764.9 EMG47141.1 - 0.066 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin His_Phos_1 PF00300.22 EMG47142.1 - 6.5e-38 130.4 0.1 9e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RTC PF01137.21 EMG47144.1 - 6.3e-44 149.8 0.0 7.9e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EMG47144.1 - 1.7e-30 105.6 0.0 2.6e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain MBOAT PF03062.19 EMG47145.1 - 1e-65 222.4 8.5 2.3e-65 221.3 8.5 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Cnd1 PF12717.7 EMG47146.1 - 2.1e-41 141.7 16.1 2.2e-40 138.3 0.3 5.4 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EMG47146.1 - 8.3e-39 133.1 0.2 4.5e-38 130.7 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 EMG47146.1 - 2.8e-06 27.6 0.4 0.14 12.6 0.0 4.0 4 1 0 4 4 3 2 HEAT repeats HEAT PF02985.22 EMG47146.1 - 1.2e-05 25.1 12.1 0.33 11.3 0.1 6.2 7 0 0 7 7 6 3 HEAT repeat HEAT_EZ PF13513.6 EMG47146.1 - 0.00015 22.2 0.9 6.6 7.4 0.0 5.4 5 0 0 5 5 5 1 HEAT-like repeat Cnd3 PF12719.7 EMG47146.1 - 0.00075 18.8 1.5 0.00075 18.8 1.5 2.8 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Proteasom_PSMB PF10508.9 EMG47146.1 - 0.0077 14.8 3.2 0.0098 14.4 1.0 2.3 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit RE_MamI PF09567.10 EMG47146.1 - 0.057 13.1 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 MamI restriction endonuclease EF-hand_6 PF13405.6 EMG47146.1 - 0.067 13.2 2.9 0.36 10.9 0.4 2.8 2 0 0 2 2 2 0 EF-hand domain DUF475 PF04332.15 EMG47146.1 - 0.07 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF475) CENP-B_dimeris PF09026.10 EMG47146.1 - 1.3 9.5 7.0 8.6 6.8 5.5 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Hep_59 PF07052.11 EMG47146.1 - 2.9 8.7 11.8 0.032 15.0 2.0 2.7 3 0 0 3 3 2 0 Hepatocellular carcinoma-associated antigen 59 TAF4 PF05236.14 EMG47147.1 - 5.8e-75 252.6 4.5 8.2e-75 252.1 4.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family NDUF_B8 PF05821.11 EMG47148.1 - 1e-05 25.5 0.4 2.1e-05 24.4 0.4 1.6 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Pkinase PF00069.25 EMG47150.1 - 6.7e-56 189.6 0.0 9.7e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG47150.1 - 4.8e-31 108.0 0.0 6.9e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EMG47150.1 - 7e-14 51.9 0.3 2e-13 50.5 0.3 1.8 1 0 0 1 1 1 1 FHA domain Haspin_kinase PF12330.8 EMG47150.1 - 5.2e-06 25.6 1.6 2.8e-05 23.3 1.6 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EMG47150.1 - 9.7e-06 25.1 0.0 5.1e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EMG47150.1 - 0.00043 19.2 0.0 0.00071 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Svf1 PF08622.10 EMG47150.1 - 0.0031 17.6 0.8 0.0075 16.3 0.7 1.7 1 1 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Yop-YscD_cpl PF16697.5 EMG47150.1 - 0.012 16.0 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 EMG47150.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.22 EMG47151.1 - 3e-31 107.0 0.0 2.2e-11 43.4 0.1 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EMG47151.1 - 0.15 12.2 0.0 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif Med4 PF10018.9 EMG47152.1 - 1e-29 103.6 10.9 1e-29 103.6 10.9 1.7 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 RasGAP_C PF03836.15 EMG47152.1 - 0.66 10.1 11.9 3.9 7.6 11.9 2.1 1 1 0 1 1 1 0 RasGAP C-terminus bZIP_1 PF00170.21 EMG47152.1 - 0.83 9.8 9.7 2.8 8.1 0.2 3.0 1 1 2 3 3 3 0 bZIP transcription factor ZapB PF06005.12 EMG47152.1 - 9.4 6.8 16.5 0.061 13.8 4.2 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Ferrochelatase PF00762.19 EMG47153.1 - 2.2e-77 260.3 0.0 2.4e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase SNF2_N PF00176.23 EMG47154.1 - 1.1e-64 218.4 0.3 1.1e-64 218.4 0.3 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 EMG47154.1 - 1.4e-12 47.9 4.0 4.7e-12 46.2 0.0 3.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.13 EMG47154.1 - 9.8e-12 45.0 10.9 9.8e-12 45.0 10.9 3.8 3 1 0 3 3 3 1 HSA DEAD PF00270.29 EMG47154.1 - 8.2e-06 25.7 0.0 2.6e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cdc13_OB4_dimer PF18233.1 EMG47154.1 - 0.019 15.1 0.1 6.8 6.9 0.0 2.9 2 0 0 2 2 2 0 Cdc13 OB4 dimerization domain DUF1684 PF07920.11 EMG47154.1 - 0.079 13.2 0.6 0.43 10.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1684) DUF3112 PF11309.8 EMG47156.1 - 1.4e-68 230.6 2.9 1.4e-68 230.6 2.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) DUF3112 PF11309.8 EMG47157.1 - 2.9e-08 33.4 2.2 4.2e-08 32.9 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) Zn_clus PF00172.18 EMG47158.1 - 0.00025 21.1 7.4 0.00052 20.1 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.18 EMG47158.1 - 0.0017 18.5 4.9 0.0017 18.5 4.9 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper DJ-1_PfpI PF01965.24 EMG47159.1 - 2e-11 44.0 0.0 4.5e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EMG47159.1 - 7.5e-05 22.5 0.1 0.00034 20.4 0.1 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 EMG47160.1 - 1.8e-09 37.7 0.0 3.6e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EMG47160.1 - 0.00085 19.1 0.1 0.0025 17.5 0.1 1.9 1 1 0 1 1 1 1 ThiJ/PfpI family-like MPC PF03650.13 EMG47161.1 - 3e-38 130.3 0.0 3.8e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Flocculin_t3 PF13928.6 EMG47162.1 - 1.1e-15 57.8 51.0 1.5e-09 38.2 22.8 14.7 9 4 6 15 15 15 3 Flocculin type 3 repeat Ogr_Delta PF04606.12 EMG47162.1 - 8.1 6.5 11.4 5.6 7.0 4.0 3.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger TLD PF07534.16 EMG47163.1 - 1.2e-25 90.3 0.9 2.4e-21 76.4 0.2 2.4 1 1 1 2 2 2 2 TLD Asp_Glu_race PF01177.22 EMG47164.1 - 1.7e-05 24.8 0.0 4.7e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Rad9 PF04139.13 EMG47165.1 - 2.9e-14 53.1 9.5 1.6e-13 50.7 9.5 2.1 1 1 0 1 1 1 1 Rad9 Metallopep PF12044.8 EMG47166.1 - 1.3e-155 518.3 0.0 1.5e-155 518.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 EMG47166.1 - 2.1e-06 27.7 0.0 4.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.6 EMG47166.1 - 0.00071 19.8 0.7 0.0015 18.7 0.7 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EMG47166.1 - 0.016 15.7 0.1 0.034 14.7 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EMG47166.1 - 0.021 13.8 0.0 0.045 12.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase M66 XPA_C PF05181.12 EMG47167.1 - 0.029 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 XPA protein C-terminus Adaptin_N PF01602.20 EMG47168.1 - 5e-99 332.2 19.5 9.6e-99 331.3 19.5 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EMG47168.1 - 3.7e-11 43.3 7.6 8.9e-11 42.1 1.9 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EMG47168.1 - 0.014 15.6 0.0 65 4.2 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Acyltransferase PF01553.21 EMG47169.1 - 1.5e-31 108.8 0.0 2.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DJ-1_PfpI PF01965.24 EMG47170.1 - 6.9e-08 32.5 0.0 4.3e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EMG47170.1 - 0.00017 21.4 0.3 0.00094 18.9 0.3 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like CelD_N PF02927.14 EMG47170.1 - 0.083 13.8 0.1 0.77 10.7 0.0 2.1 2 0 0 2 2 2 0 Cellulase N-terminal ig-like domain Flocculin_t3 PF13928.6 EMG47171.1 - 1.5e-08 35.0 27.8 1.5e-08 35.0 27.8 4.7 6 0 0 6 6 6 1 Flocculin type 3 repeat Flocculin_t3 PF13928.6 EMG47172.1 - 2.6e-11 43.8 25.7 2.6e-11 43.8 25.7 3.1 4 0 0 4 4 4 1 Flocculin type 3 repeat MAP70 PF07058.11 EMG47172.1 - 3.2 6.4 8.2 3.9 6.1 8.2 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 Acid_PPase PF12689.7 EMG47173.1 - 1.8e-53 180.8 0.0 2.1e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 EMG47173.1 - 0.099 12.4 0.5 0.24 11.2 0.5 1.8 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase ADH_zinc_N PF00107.26 EMG47175.1 - 1.2e-25 89.9 0.0 2.1e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMG47175.1 - 4.4e-16 60.1 0.0 8.9e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG47175.1 - 1.7e-09 37.5 0.0 3.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CdhD PF03599.16 EMG47175.1 - 0.0023 16.7 0.0 0.0034 16.1 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit adh_short PF00106.25 EMG47175.1 - 0.0041 16.6 0.1 0.0076 15.7 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase QueH PF02677.14 EMG47175.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH Cpn10 PF00166.21 EMG47175.1 - 0.12 12.4 1.0 1.2 9.2 0.1 2.7 2 1 0 2 2 2 0 Chaperonin 10 Kd subunit Cyt-b5 PF00173.28 EMG47176.1 - 2.7e-13 49.8 0.0 5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EMG47176.1 - 1.8e-12 47.6 5.7 3.6e-12 46.7 5.7 1.4 1 0 0 1 1 1 1 Fatty acid desaturase SNF2_N PF00176.23 EMG47177.1 - 8.7e-47 159.5 0.0 4e-45 154.1 0.0 2.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 EMG47177.1 - 6.7e-08 32.7 16.7 1.6e-07 31.6 16.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMG47177.1 - 1.4e-07 31.2 17.0 3e-07 30.2 17.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMG47177.1 - 2e-07 30.7 13.3 3.7e-07 29.9 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 EMG47177.1 - 8.2e-07 29.3 0.0 2.8e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EMG47177.1 - 2e-06 27.5 16.8 5.6e-06 26.1 16.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMG47177.1 - 3.6e-05 23.9 11.1 0.0001 22.5 11.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EMG47177.1 - 0.00019 21.2 14.2 0.00039 20.2 14.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EMG47177.1 - 0.0009 19.2 13.4 0.002 18.1 13.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMG47177.1 - 0.0048 16.8 15.7 0.01 15.7 15.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EMG47177.1 - 0.0058 16.4 4.5 0.022 14.6 4.5 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain WW PF00397.26 EMG47177.1 - 0.27 11.4 0.7 0.74 10.0 0.7 1.7 1 0 0 1 1 1 0 WW domain zf-ANAPC11 PF12861.7 EMG47177.1 - 0.5 10.4 7.6 1.4 9.1 7.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EMG47177.1 - 0.88 9.8 13.0 2.5 8.3 13.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 EMG47177.1 - 4 7.2 11.7 9 6.0 11.7 1.5 1 0 0 1 1 1 0 P-11 zinc finger tRNA_anti-codon PF01336.25 EMG47178.1 - 0.00045 20.2 0.1 0.00069 19.6 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SWIB PF02201.18 EMG47180.1 - 1.1e-07 31.6 0.6 0.00025 20.9 0.1 2.6 2 0 0 2 2 2 2 SWIB/MDM2 domain WSN PF02206.18 EMG47180.1 - 0.21 11.5 1.3 3.3 7.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF3112 PF11309.8 EMG47181.1 - 5.8e-14 52.1 1.1 7.8e-14 51.6 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) DUF3112 PF11309.8 EMG47182.1 - 8e-11 41.8 4.3 1.2e-10 41.3 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) CENP-B_dimeris PF09026.10 EMG47182.1 - 8.9 6.8 11.1 28 5.2 6.3 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1682 PF07946.14 EMG47183.1 - 1.4e-87 294.0 9.1 1.4e-87 294.0 9.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) Ank_5 PF13857.6 EMG47183.1 - 1.8e-15 56.8 0.1 4.4e-12 46.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMG47183.1 - 2.3e-12 47.3 0.1 5.3e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMG47183.1 - 2.5e-11 43.9 0.1 6.4e-09 36.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EMG47183.1 - 1.4e-08 34.8 0.7 2.1e-06 27.9 0.3 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EMG47183.1 - 3.3e-08 33.2 1.3 4.7e-06 26.5 0.1 3.7 3 1 0 3 3 3 1 Ankyrin repeat DUF3692 PF12469.8 EMG47183.1 - 0.0081 16.4 0.1 0.038 14.2 0.0 2.2 2 0 0 2 2 2 1 CRISPR-associated protein Atrophin-1 PF03154.15 EMG47183.1 - 0.16 10.2 6.8 0.2 9.9 6.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family Stk19 PF10494.9 EMG47184.1 - 7.5e-75 251.8 0.1 1.2e-74 251.2 0.1 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Ribosomal_L9_N PF01281.19 EMG47185.1 - 1.5e-13 50.1 0.0 3.3e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain IL33 PF15095.6 EMG47185.1 - 0.052 13.0 0.1 0.077 12.4 0.1 1.2 1 0 0 1 1 1 0 Interleukin 33 zf-HIT PF04438.16 EMG47186.1 - 4.8e-09 35.9 9.8 6.9e-09 35.4 9.8 1.2 1 0 0 1 1 1 1 HIT zinc finger BUD22 PF09073.10 EMG47186.1 - 0.0037 16.7 3.8 0.0037 16.7 3.8 1.6 2 0 0 2 2 2 1 BUD22 AF-4 PF05110.13 EMG47186.1 - 0.84 7.6 22.8 0.016 13.3 12.6 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DNA_pol_phi PF04931.13 EMG47186.1 - 0.85 7.6 12.7 1.6 6.7 12.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi RRM_1 PF00076.22 EMG47187.1 - 4.9e-17 61.5 0.0 7.7e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMG47187.1 - 0.00038 20.1 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMG47187.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ZZ PF00569.17 EMG47188.1 - 6.9e-08 32.2 10.0 2.2e-07 30.6 10.0 1.9 1 0 0 1 1 1 1 Zinc finger, ZZ type Asp PF00026.23 EMG47189.1 - 5.9e-88 295.3 13.6 6.8e-88 295.1 13.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMG47189.1 - 1.3e-09 38.5 5.9 4.8e-09 36.7 5.9 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EMG47189.1 - 0.00019 21.2 0.1 0.016 15.0 0.0 2.5 2 1 1 3 3 3 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EMG47189.1 - 0.0016 19.0 1.9 10 6.8 0.1 4.2 2 2 1 3 3 3 2 gag-polyprotein putative aspartyl protease DUF3112 PF11309.8 EMG47190.1 - 8.1e-91 303.3 8.9 8.1e-91 303.3 8.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) Abhydrolase_1 PF00561.20 EMG47191.1 - 1.1e-17 64.5 0.1 4.8e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG47191.1 - 0.0004 19.7 0.0 0.0013 18.0 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMG47191.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EMG47191.1 - 0.24 12.0 0.0 0.41 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family A_deaminase PF00962.22 EMG47192.1 - 1.7e-85 287.2 0.0 2e-85 287.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase GRDP-like PF07173.12 EMG47193.1 - 0.00018 22.2 6.2 0.00089 19.9 0.1 3.6 4 0 0 4 4 4 1 Glycine-rich domain-containing protein-like BAR PF03114.18 EMG47194.1 - 1.2e-05 25.1 7.9 1.6e-05 24.7 6.6 1.9 1 1 1 2 2 2 1 BAR domain CEP63 PF17045.5 EMG47194.1 - 0.012 15.5 4.0 0.027 14.4 4.0 1.5 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Seryl_tRNA_N PF02403.22 EMG47194.1 - 0.012 15.8 4.7 0.4 10.9 4.3 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ArenaCapSnatch PF17296.2 EMG47194.1 - 0.033 13.6 0.1 0.088 12.2 0.1 1.7 1 0 0 1 1 1 0 Arenavirus cap snatching domain CALCOCO1 PF07888.11 EMG47194.1 - 0.18 10.6 5.8 0.22 10.3 4.5 1.6 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like SBDS PF01172.18 EMG47195.1 - 4e-15 55.7 0.4 5.3e-15 55.3 0.4 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.20 EMG47196.1 - 3.8e-09 37.1 3.2 8.3e-09 35.9 3.2 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 EMG47196.1 - 0.051 14.1 0.1 0.13 12.7 0.1 1.8 1 0 0 1 1 1 0 PH domain Aldedh PF00171.22 EMG47197.1 - 2.3e-126 422.1 0.0 3.6e-126 421.4 0.0 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tcf25 PF04910.14 EMG47197.1 - 6.2e-101 338.0 5.7 8.9e-101 337.4 5.7 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Peptidase_C37 PF05416.12 EMG47197.1 - 0.44 9.0 9.3 0.76 8.2 9.3 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Rgp1 PF08737.10 EMG47197.1 - 2.1 7.5 7.5 3.9 6.5 7.5 1.5 1 0 0 1 1 1 0 Rgp1 V-ATPase_G PF03179.15 EMG47198.1 - 2e-30 105.4 11.0 2.2e-30 105.3 11.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 EMG47198.1 - 0.0011 18.4 10.7 0.0015 18.0 10.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) vATP-synt_E PF01991.18 EMG47198.1 - 0.002 17.6 9.8 0.0025 17.3 9.8 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit V-ATPase_G_2 PF16999.5 EMG47198.1 - 0.007 16.8 7.3 0.0079 16.6 7.3 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EMG47198.1 - 0.018 15.1 11.8 0.24 11.5 12.2 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) PHM7_cyt PF14703.6 EMG47198.1 - 0.022 15.0 5.6 0.024 14.9 5.6 1.1 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF89 PF01937.19 EMG47198.1 - 0.029 13.3 1.9 0.032 13.2 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 HIP1_clath_bdg PF16515.5 EMG47198.1 - 0.12 13.0 8.0 0.22 12.2 8.0 1.5 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1640 PF07798.11 EMG47198.1 - 0.17 11.9 7.1 0.21 11.6 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4407 PF14362.6 EMG47198.1 - 0.2 11.0 5.1 0.24 10.7 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 EMG47198.1 - 0.27 10.5 7.2 0.29 10.4 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 EMG47198.1 - 1.4 9.0 11.1 3.1 7.9 11.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 EMG47198.1 - 2.5 7.3 6.4 2.9 7.0 6.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4337 PF14235.6 EMG47198.1 - 5.8 7.0 8.8 8.1 6.5 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF883 PF05957.13 EMG47198.1 - 9.8 6.9 8.1 16 6.2 2.9 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MBOAT PF03062.19 EMG47199.1 - 1.6e-50 172.4 27.5 2e-45 155.7 11.6 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EMG47199.1 - 0.00047 20.4 1.1 0.0013 18.9 1.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CAML PF14963.6 EMG47199.1 - 0.0084 16.3 1.1 0.013 15.6 1.1 1.2 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand FXR_C1 PF16096.5 EMG47199.1 - 0.084 13.1 6.1 0.16 12.2 6.1 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Peptidase_M76 PF09768.9 EMG47200.1 - 2.1e-66 222.9 0.7 2.6e-66 222.6 0.7 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EMG47200.1 - 0.043 13.7 0.2 0.077 12.9 0.2 1.6 1 1 0 1 1 1 0 SprT-like family Peptidase_M91 PF14891.6 EMG47200.1 - 0.089 13.1 0.1 0.15 12.4 0.1 1.4 1 1 0 1 1 1 0 Effector protein Spermine_synth PF01564.17 EMG47201.1 - 1.2e-76 256.4 0.1 2.2e-76 255.5 0.0 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EMG47201.1 - 2.9e-23 81.5 0.1 5.1e-23 80.7 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_31 PF13847.6 EMG47201.1 - 7.9e-05 22.5 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG47201.1 - 0.00066 20.3 0.0 0.0015 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG47201.1 - 0.0012 19.6 0.0 0.0027 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 EMG47201.1 - 0.032 14.1 0.0 0.09 12.7 0.0 1.7 1 1 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 EMG47201.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EMG47202.1 - 3.4e-48 163.3 0.0 4.9e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EMG47202.1 - 3.1e-05 24.6 0.0 0.0001 23.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMG47202.1 - 0.00013 21.8 0.0 0.0016 18.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.16 EMG47202.1 - 0.001 18.4 1.1 0.0029 16.9 0.0 2.2 2 1 0 2 2 2 1 N-6 DNA Methylase FAM176 PF14851.6 EMG47202.1 - 0.0082 15.8 3.5 0.0082 15.8 3.5 2.6 2 1 0 2 2 1 1 FAM176 family Methyltr_RsmB-F PF01189.17 EMG47202.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F MTS PF05175.14 EMG47202.1 - 0.016 14.7 0.0 0.12 11.9 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.12 EMG47202.1 - 0.11 13.2 0.0 0.44 11.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EMG47202.1 - 0.14 11.4 0.0 0.8 9.0 0.0 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family BUD22 PF09073.10 EMG47202.1 - 1.8 7.8 23.3 1 8.6 2.0 2.1 2 0 0 2 2 2 0 BUD22 DUF1754 PF08555.10 EMG47202.1 - 2.6 8.9 26.1 0.16 12.8 6.6 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) CDC45 PF02724.14 EMG47202.1 - 6.6 4.9 19.2 0.66 8.2 9.8 2.1 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 EMG47202.1 - 6.6 6.0 28.9 3.4 7.0 15.7 2.1 2 0 0 2 2 2 0 SDA1 SpoIIIAH PF12685.7 EMG47202.1 - 6.9 6.4 15.7 4.1 7.2 4.4 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein CobT PF06213.12 EMG47202.1 - 7.5 5.8 22.7 1.1 8.6 12.6 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 EMG47202.1 - 9.4 6.7 11.1 6.3 7.2 1.3 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF2439 PF10382.9 EMG47204.1 - 1.8e-21 76.2 1.2 1.8e-21 76.2 1.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) Ribosomal_L5_C PF00673.21 EMG47205.1 - 3.6e-27 94.4 0.0 4.9e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EMG47205.1 - 0.0019 18.5 0.0 0.0038 17.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 GLE1 PF07817.13 EMG47206.1 - 6.4e-82 274.5 1.0 6.4e-82 274.5 1.0 1.7 2 0 0 2 2 2 1 GLE1-like protein CDC45 PF02724.14 EMG47206.1 - 0.022 13.1 28.1 0.034 12.5 28.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EMG47206.1 - 9 4.9 23.0 13 4.4 23.0 1.3 1 0 0 1 1 1 0 Presenilin HEAT_2 PF13646.6 EMG47207.1 - 2.6e-08 34.2 0.0 0.0034 17.7 0.0 4.4 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 EMG47207.1 - 1.4e-07 31.2 0.0 3.5 8.1 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat CLASP_N PF12348.8 EMG47207.1 - 8.5e-05 22.2 3.2 0.24 10.9 0.0 3.9 3 1 1 4 4 4 2 CLASP N terminal Cnd1 PF12717.7 EMG47207.1 - 0.0046 17.0 5.6 0.0046 17.0 5.6 4.8 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EMG47207.1 - 0.03 14.9 0.0 78 3.9 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat EF-hand_2 PF09068.11 EMG47207.1 - 0.37 11.0 2.3 11 6.2 0.2 3.0 2 0 0 2 2 2 0 EF hand NST1 PF13945.6 EMG47208.1 - 1.7e-12 47.8 35.9 2.5e-08 34.3 28.6 9.0 4 3 5 9 9 9 2 Salt tolerance down-regulator Ras PF00071.22 EMG47209.1 - 1.1e-48 164.9 0.0 1.2e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG47209.1 - 7e-23 81.1 0.0 9.6e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG47209.1 - 8.9e-06 25.3 0.0 1.2e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EMG47209.1 - 0.013 15.3 0.0 4.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EMG47209.1 - 0.066 12.6 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit EamA PF00892.20 EMG47210.1 - 4.3e-24 85.2 39.4 7.3e-15 55.3 11.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF1180 PF06679.12 EMG47210.1 - 1.7 9.1 4.0 38 4.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Cation_ATPase_C PF00689.21 EMG47210.1 - 2.3 7.9 21.4 0.25 11.0 12.8 3.3 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus BLOC1_2 PF10046.9 EMG47211.1 - 0.0023 18.2 0.5 0.0026 18.0 0.5 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 MobC PF05713.11 EMG47211.1 - 0.0085 16.5 2.4 0.021 15.3 2.4 1.8 1 1 0 1 1 1 1 Bacterial mobilisation protein (MobC) DUF948 PF06103.11 EMG47211.1 - 0.11 12.8 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) KIF1B PF12423.8 EMG47212.1 - 0.15 12.5 1.4 1.4 9.4 1.4 2.9 1 0 0 1 1 1 0 Kinesin protein 1B Ion_trans PF00520.31 EMG47213.1 - 1.4e-07 31.0 27.1 3.5e-07 29.7 27.1 1.6 1 1 0 1 1 1 1 Ion transport protein GCR1_C PF12550.8 EMG47214.1 - 8e-20 71.0 0.3 1.8e-19 69.8 0.3 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Med15 PF09606.10 EMG47214.1 - 0.14 10.8 38.6 0.18 10.5 38.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Med19 PF10278.9 EMG47214.1 - 0.23 11.4 13.3 1.5 8.7 5.1 2.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF948 PF06103.11 EMG47214.1 - 0.54 10.5 6.5 0.31 11.3 0.5 3.1 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Ndc1_Nup PF09531.10 EMG47214.1 - 0.57 8.8 14.1 0.65 8.6 14.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 EMG47214.1 - 1.4 5.9 23.8 1.9 5.5 23.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S46 PF10459.9 EMG47214.1 - 3.2 6.3 20.3 4.3 5.9 20.3 1.1 1 0 0 1 1 1 0 Peptidase S46 FMN_red PF03358.15 EMG47215.1 - 1.1e-10 41.5 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMG47215.1 - 4.3e-05 23.3 0.0 5.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Peptidase_S8 PF00082.22 EMG47216.1 - 1.6e-27 96.6 8.4 4.6e-27 95.1 8.4 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMG47216.1 - 3.6e-11 43.6 0.2 6.4e-11 42.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Aldo_ket_red PF00248.21 EMG47217.1 - 7.5e-32 110.7 0.0 4.3e-26 91.8 0.1 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family LsmAD PF06741.13 EMG47217.1 - 0.0084 16.6 0.1 0.021 15.4 0.1 1.6 1 0 0 1 1 1 1 LsmAD domain Abhydrolase_1 PF00561.20 EMG47218.1 - 2.6e-12 47.0 0.1 4.1e-11 43.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG47218.1 - 1.7e-07 30.8 0.0 4.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMG47218.1 - 3.7e-05 24.4 0.0 5.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 EMG47218.1 - 0.0038 17.2 0.0 0.006 16.6 0.0 1.2 1 0 0 1 1 1 1 Cutinase Peptidase_S15 PF02129.18 EMG47218.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 EMG47218.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 EMG47218.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Lipase (class 3) VirJ PF06057.11 EMG47218.1 - 0.12 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Asp PF00026.23 EMG47219.1 - 3.9e-102 341.9 0.2 4.9e-102 341.6 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMG47219.1 - 2e-14 54.2 0.5 1e-08 35.6 0.2 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMG47219.1 - 7e-05 23.4 0.0 0.076 13.7 0.0 2.5 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EMG47219.1 - 0.00052 20.5 0.0 0.067 13.8 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EMG47219.1 - 0.0072 16.1 0.0 0.064 13.0 0.0 2.3 1 1 0 2 2 2 1 Xylanase inhibitor C-terminal HSP70 PF00012.20 EMG47221.1 - 1.6e-265 882.0 14.3 1.8e-265 881.8 14.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMG47221.1 - 2.4e-15 56.2 6.1 1e-13 50.8 4.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EMG47221.1 - 0.0011 18.7 0.1 0.0037 17.0 0.0 1.9 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain Gp-FAR-1 PF05823.12 EMG47221.1 - 0.024 15.0 3.6 0.061 13.7 3.6 1.7 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FtsA PF14450.6 EMG47221.1 - 0.024 15.1 10.8 0.17 12.3 0.7 4.3 3 2 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 EMG47221.1 - 0.048 12.9 7.1 0.12 11.6 0.1 3.3 3 1 1 4 4 4 0 StbA protein Ribosomal_L9_C PF03948.14 EMG47221.1 - 0.16 12.5 1.5 0.3 11.6 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain Extensin_2 PF04554.13 EMG47222.1 - 0.16 12.1 18.3 0.19 11.8 18.3 1.1 1 0 0 1 1 1 0 Extensin-like region Pro-rich PF15240.6 EMG47222.1 - 0.58 10.4 18.7 0.77 10.0 18.7 1.1 1 0 0 1 1 1 0 Proline-rich DUF2076 PF09849.9 EMG47222.1 - 3.3 7.7 9.2 3.4 7.6 9.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SMC_N PF02463.19 EMG47223.1 - 6.9e-48 163.0 75.2 9.7e-47 159.2 75.2 3.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EMG47223.1 - 7.6e-28 97.2 0.1 7.6e-28 97.2 0.1 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EMG47223.1 - 4.2e-17 62.9 3.0 6.6e-12 45.8 0.3 4.0 3 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMG47223.1 - 1.3e-13 52.0 24.9 1.3e-13 52.0 24.9 7.8 2 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 EMG47223.1 - 1.4e-11 44.7 26.4 1.4e-11 44.7 26.4 4.4 2 2 2 4 4 4 2 AAA ATPase domain GAS PF13851.6 EMG47223.1 - 0.00015 21.2 8.2 0.00015 21.2 8.2 7.9 3 2 5 8 8 8 2 Growth-arrest specific micro-tubule binding AAA_29 PF13555.6 EMG47223.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain BRCT PF00533.26 EMG47223.1 - 1.2 9.6 9.5 9.7 6.7 0.0 5.4 5 0 0 5 5 5 0 BRCA1 C Terminus (BRCT) domain PTS_IIA PF02255.16 EMG47223.1 - 1.3 9.2 10.2 5.2 7.2 2.4 3.9 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit FA_desaturase PF00487.24 EMG47225.1 - 3.2e-28 99.3 25.8 4.4e-28 98.8 25.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EMG47225.1 - 7e-12 45.3 0.2 1.8e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NUFIP1 PF10453.9 EMG47226.1 - 1.4e-19 69.6 9.7 3.4e-19 68.4 9.7 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) ANAPC_CDC26 PF10471.9 EMG47226.1 - 0.014 16.2 4.2 0.049 14.5 4.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 WD40 PF00400.32 EMG47227.1 - 3.1e-21 75.3 14.8 2.7e-05 24.8 0.2 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG47227.1 - 1.2e-09 38.3 0.2 0.055 13.8 0.0 4.4 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMG47227.1 - 9.5e-06 24.5 1.8 0.5 8.9 0.1 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 tRNA-synt_2b PF00587.25 EMG47228.1 - 6.4e-34 117.5 0.5 2.5e-33 115.5 0.0 2.1 2 1 1 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EMG47228.1 - 1.8e-23 82.8 7.5 1.8e-23 82.8 7.5 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Ribonuclease_3 PF00636.26 EMG47230.1 - 7.4e-05 23.3 0.1 0.00029 21.4 0.0 2.1 3 0 0 3 3 3 1 Ribonuclease III domain IL15 PF02372.15 EMG47230.1 - 0.08 13.0 1.7 1.1 9.3 0.2 2.5 1 1 1 2 2 2 0 Interleukin 15 Cytokin_check_N PF10407.9 EMG47231.1 - 1.9e-24 85.4 1.8 1.9e-24 85.4 1.8 2.3 2 0 0 2 2 2 1 Cdc14 phosphatase binding protein N-terminus Par3_HAL_N_term PF12053.8 EMG47231.1 - 0.068 13.4 0.1 0.28 11.4 0.1 2.1 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins Cyclin PF08613.11 EMG47232.1 - 2.1e-16 60.7 3.0 5e-16 59.5 3.0 1.6 1 0 0 1 1 1 1 Cyclin adh_short_C2 PF13561.6 EMG47233.1 - 1.1e-31 110.2 0.0 1.3e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMG47233.1 - 1.8e-25 89.6 0.0 2.1e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG47233.1 - 2.5e-07 30.8 0.0 3.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 EMG47233.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family GYD PF08734.11 EMG47233.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 GYD domain Sybindin PF04099.12 EMG47234.1 - 1.3e-17 64.0 1.4 1.6e-17 63.8 1.4 1.1 1 0 0 1 1 1 1 Sybindin-like family PAC1 PF16094.5 EMG47236.1 - 0.86 8.7 4.9 0.44 9.7 2.2 1.8 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Trypan_PARP PF05887.11 EMG47236.1 - 6.4 6.8 8.5 12 5.9 8.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ELO PF01151.18 EMG47237.1 - 2.4e-67 227.1 15.7 3e-67 226.8 15.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family AATase PF07247.12 EMG47238.1 - 2.7e-53 181.2 11.4 3.3e-53 181.0 11.4 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Transferase PF02458.15 EMG47238.1 - 0.0025 16.6 0.0 0.0042 15.8 0.0 1.4 1 0 0 1 1 1 1 Transferase family Tri3 PF07428.11 EMG47238.1 - 0.058 12.3 0.0 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 2-oxoacid_dh PF00198.23 EMG47238.1 - 0.16 11.4 0.2 8.3 5.8 0.0 2.4 2 0 0 2 2 2 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) HK PF02110.15 EMG47239.1 - 9.9e-76 254.4 1.9 1.8e-75 253.5 1.9 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EMG47239.1 - 5e-54 182.4 0.1 7.4e-54 181.8 0.1 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 EMG47239.1 - 0.0002 20.9 1.0 0.00037 20.0 0.5 1.7 2 0 0 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EMG47239.1 - 0.00065 19.2 0.1 0.0018 17.7 0.1 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase WD40 PF00400.32 EMG47240.1 - 1e-20 73.6 12.1 0.00086 20.1 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 EMG47240.1 - 0.066 13.3 0.0 8.6 6.4 0.0 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF2415 PF10313.9 EMG47240.1 - 0.14 12.1 0.0 14 5.7 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) Choline_kinase PF01633.20 EMG47241.1 - 1.4e-54 184.9 0.5 2.3e-54 184.2 0.5 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EMG47241.1 - 9.7e-15 54.0 0.2 1.9e-14 53.0 0.2 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EMG47241.1 - 1e-05 25.6 0.5 7.1e-05 22.8 0.5 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Glyco_transf_24 PF18404.1 EMG47243.1 - 8.5e-140 464.7 4.2 2.7e-139 463.1 3.7 2.1 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_12 PF18400.1 EMG47243.1 - 2.5e-31 109.0 0.0 5.7e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_14 PF18402.1 EMG47243.1 - 1.6e-27 97.1 1.5 2.1e-26 93.4 0.0 3.2 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EMG47243.1 - 1.6e-18 67.0 0.3 5e-18 65.3 0.3 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EMG47243.1 - 1.6e-14 53.9 0.0 3.6e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 EMG47243.1 - 7.8e-11 42.0 0.4 1.7e-10 40.9 0.4 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 WLM PF08325.10 EMG47244.1 - 1.5e-55 188.2 0.1 1.9e-55 187.9 0.1 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EMG47244.1 - 0.012 15.6 0.1 0.04 14.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF45 Peptidase_M54 PF07998.11 EMG47244.1 - 0.027 14.5 0.5 0.076 13.0 0.3 1.7 1 1 1 2 2 2 0 Peptidase family M54 Tyr_Deacylase PF02580.16 EMG47245.1 - 1e-52 178.5 0.0 1.1e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase MTHFR PF02219.17 EMG47246.1 - 1.9e-117 391.7 0.0 2.8e-117 391.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Flocculin_t3 PF13928.6 EMG47248.1 - 1.1e-30 105.9 136.8 2.8e-11 43.7 29.8 16.7 12 3 1 13 13 13 4 Flocculin type 3 repeat zf-RING_5 PF14634.6 EMG47248.1 - 3.2 7.8 10.7 0.09 12.7 0.3 3.3 3 0 0 3 3 3 0 zinc-RING finger domain DUF1765 PF08578.10 EMG47249.1 - 2.9e-44 150.5 11.2 2.9e-44 150.5 11.2 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1765) AA_permease_C PF13906.6 EMG47249.1 - 3 8.0 6.1 1.5 9.0 1.3 2.4 2 0 0 2 2 2 0 C-terminus of AA_permease ABC2_membrane PF01061.24 EMG47251.1 - 3.6e-82 274.8 63.4 4e-44 150.5 22.2 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EMG47251.1 - 2.9e-39 134.7 0.0 1e-18 68.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EMG47251.1 - 3.9e-39 132.4 2.9 2.2e-32 110.8 0.3 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EMG47251.1 - 1.2e-21 77.1 0.0 4.3e-21 75.3 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EMG47251.1 - 1.8e-07 31.2 0.0 0.00027 20.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EMG47251.1 - 3.2e-06 26.8 0.5 5.7e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EMG47251.1 - 1.8e-05 25.3 1.2 0.033 14.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EMG47251.1 - 3.9e-05 24.1 0.1 0.0025 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EMG47251.1 - 0.00025 20.7 0.2 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EMG47251.1 - 0.00028 20.8 0.0 0.05 13.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 EMG47251.1 - 0.00061 18.7 0.6 0.0066 15.3 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Rep_2 PF01719.17 EMG47251.1 - 0.00069 19.5 0.1 0.00069 19.5 0.1 2.3 3 0 0 3 3 2 1 Plasmid replication protein AAA_28 PF13521.6 EMG47251.1 - 0.00088 19.6 0.9 0.032 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMG47251.1 - 0.0014 18.9 1.3 0.32 11.3 0.1 3.4 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 EMG47251.1 - 0.0019 17.9 0.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EMG47251.1 - 0.0026 17.8 0.2 0.99 9.5 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 EMG47251.1 - 0.004 16.6 0.0 0.19 11.1 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain dNK PF01712.19 EMG47251.1 - 0.0052 16.7 0.0 2 8.2 0.0 2.6 2 0 0 2 2 2 1 Deoxynucleoside kinase NACHT PF05729.12 EMG47251.1 - 0.011 15.7 2.4 4.7 7.1 0.1 3.6 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 EMG47251.1 - 0.012 16.1 0.1 0.54 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain fn3 PF00041.21 EMG47251.1 - 0.022 15.1 0.1 0.058 13.7 0.1 1.7 1 0 0 1 1 1 0 Fibronectin type III domain AAA_24 PF13479.6 EMG47251.1 - 0.026 14.3 0.2 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EMG47251.1 - 0.031 14.7 0.6 19 5.7 0.0 3.6 3 1 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EMG47251.1 - 0.089 13.0 0.1 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EMG47251.1 - 0.094 12.3 3.3 1.7 8.2 0.5 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EMG47251.1 - 0.2 11.6 0.2 4.5 7.2 0.0 2.7 3 0 0 3 3 3 0 NTPase ABC2_membrane_3 PF12698.7 EMG47251.1 - 5.1 6.1 55.0 1.2 8.2 20.3 3.3 2 1 0 2 2 2 0 ABC-2 family transporter protein TPR_2 PF07719.17 EMG47252.1 - 1.2e-22 78.1 28.0 0.00089 19.2 0.0 12.3 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 EMG47252.1 - 2e-18 66.7 8.1 0.00011 22.7 0.0 7.5 8 1 1 9 9 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMG47252.1 - 6.3e-17 61.9 0.0 0.011 16.3 0.0 6.4 7 1 0 7 7 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EMG47252.1 - 1e-15 56.7 25.5 0.007 16.1 0.1 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 EMG47252.1 - 2.3e-13 49.2 28.3 0.0014 18.7 0.0 10.8 12 0 0 12 12 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 EMG47252.1 - 1.6e-12 47.6 21.9 0.00078 19.7 0.4 9.5 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 EMG47252.1 - 2.4e-12 46.6 10.5 0.013 16.1 0.0 9.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMG47252.1 - 3e-12 46.0 8.8 0.0076 15.9 0.1 6.7 6 0 0 6 6 6 4 TPR repeat TPR_14 PF13428.6 EMG47252.1 - 3e-11 43.1 1.1 0.69 10.9 0.0 9.2 7 2 3 10 10 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMG47252.1 - 3.1e-11 42.8 16.6 0.0038 17.5 0.2 10.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMG47252.1 - 2.9e-10 39.4 6.7 0.36 11.0 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG47252.1 - 1.2e-06 28.6 17.3 0.00048 20.3 0.8 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EMG47252.1 - 0.00085 19.4 0.6 62 3.8 0.0 5.4 4 1 2 6 6 5 0 Tetratricopeptide repeat BTAD PF03704.17 EMG47252.1 - 0.0016 18.9 0.4 0.68 10.4 0.1 3.2 3 0 0 3 3 3 1 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 EMG47252.1 - 0.031 14.7 0.6 2.4 8.6 0.0 3.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 EMG47252.1 - 0.071 13.2 0.7 0.44 10.7 0.0 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EMG47252.1 - 0.13 12.3 7.3 5.3 7.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF484 PF04340.12 EMG47252.1 - 0.15 11.7 1.0 0.34 10.6 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF484 TPR_4 PF07721.14 EMG47252.1 - 0.18 12.5 0.0 7 7.6 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat AMP-binding PF00501.28 EMG47254.1 - 9e-74 248.6 0.0 1.4e-73 248.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme zf-C2H2 PF00096.26 EMG47256.1 - 0.0046 17.3 1.2 0.0046 17.3 1.2 6.3 7 0 0 7 7 7 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EMG47256.1 - 0.011 15.8 0.2 0.011 15.8 0.2 4.0 4 1 1 5 5 5 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EMG47256.1 - 0.041 14.7 0.5 0.041 14.7 0.5 6.0 6 1 0 6 6 6 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMG47256.1 - 0.059 13.8 0.3 0.059 13.8 0.3 5.1 5 0 0 5 5 5 0 Zinc-finger double domain Macoilin PF09726.9 EMG47256.1 - 0.43 9.1 38.8 0.063 11.8 24.4 2.2 2 0 0 2 2 2 0 Macoilin family AF-4 PF05110.13 EMG47256.1 - 7.6 4.5 49.1 0.31 9.1 25.2 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein F-box-like PF12937.7 EMG47258.1 - 2.3e-05 24.2 0.7 2.3e-05 24.2 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EMG47258.1 - 0.00019 21.2 1.3 0.066 13.1 0.2 3.0 2 0 0 2 2 2 2 F-box domain F-box_4 PF15966.5 EMG47258.1 - 0.19 11.6 4.1 0.42 10.5 0.3 3.1 3 0 0 3 3 3 0 F-box FAS_I_H PF18314.1 EMG47259.1 - 8.4e-76 254.1 0.3 8.4e-76 254.1 0.3 2.2 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EMG47259.1 - 5.5e-74 247.9 0.0 1.2e-73 246.8 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EMG47259.1 - 5.6e-21 75.3 0.0 1.1e-20 74.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EMG47259.1 - 2.5e-18 66.3 0.0 6.6e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EMG47259.1 - 2.2e-11 43.8 1.0 7.3e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EMG47259.1 - 7.9e-07 28.7 0.0 2.1e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG47259.1 - 0.0028 17.6 0.0 0.0093 15.9 0.0 1.9 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EMG47259.1 - 0.044 14.4 0.2 0.18 12.4 0.2 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Topoisom_bac PF01131.20 EMG47260.1 - 1.9e-107 359.8 0.0 2.3e-107 359.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EMG47260.1 - 3.7e-19 68.9 0.0 2.6e-18 66.1 0.0 2.3 2 0 0 2 2 2 1 Toprim domain FNIP_C PF14638.6 EMG47260.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus SecA_SW PF07516.13 EMG47261.1 - 0.0024 18.0 7.8 0.0034 17.5 3.0 2.3 2 0 0 2 2 2 1 SecA Wing and Scaffold domain PspA_IM30 PF04012.12 EMG47261.1 - 0.0045 16.6 0.8 0.011 15.3 0.8 1.8 1 0 0 1 1 1 1 PspA/IM30 family ApoO PF09769.9 EMG47261.1 - 0.0059 16.6 1.1 1.7 8.6 0.1 2.7 2 0 0 2 2 2 1 Apolipoprotein O DASH_Dad2 PF08654.10 EMG47261.1 - 0.0094 16.3 0.6 6.2 7.3 0.1 3.0 2 0 0 2 2 2 0 DASH complex subunit Dad2 PI3K_P85_iSH2 PF16454.5 EMG47261.1 - 0.0096 15.5 7.2 0.028 14.0 7.2 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF724 PF05266.14 EMG47261.1 - 0.01 15.7 4.3 0.027 14.3 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SOAR PF16533.5 EMG47261.1 - 0.021 14.8 1.2 0.083 12.9 1.2 2.1 1 0 0 1 1 1 0 STIM1 Orai1-activating region GPS2_interact PF15784.5 EMG47261.1 - 0.022 15.2 2.0 0.093 13.2 2.0 2.2 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Ead_Ea22 PF13935.6 EMG47261.1 - 0.022 15.4 3.6 0.034 14.8 2.1 2.0 2 0 0 2 2 2 0 Ead/Ea22-like protein SWIRM PF04433.17 EMG47261.1 - 0.027 14.8 0.8 0.13 12.6 0.2 2.5 2 1 0 2 2 1 0 SWIRM domain ATG16 PF08614.11 EMG47261.1 - 0.027 14.7 3.0 0.082 13.1 3.0 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 EMG47261.1 - 0.029 13.7 1.7 0.053 12.8 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF573 PF04504.14 EMG47261.1 - 0.041 14.5 7.1 4.8 7.9 1.8 3.5 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Nmad5 PF18757.1 EMG47261.1 - 0.047 13.9 2.7 0.15 12.3 2.7 1.9 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 APG6_N PF17675.1 EMG47261.1 - 0.07 13.7 8.6 0.15 12.6 7.7 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region HR1 PF02185.16 EMG47261.1 - 0.076 13.1 3.9 0.6 10.3 1.1 2.7 2 0 0 2 2 2 0 Hr1 repeat NPV_P10 PF05531.12 EMG47261.1 - 0.11 13.0 2.8 4.5 7.8 0.2 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ZapB PF06005.12 EMG47261.1 - 0.12 12.8 6.2 3.9 8.0 1.6 4.1 4 0 0 4 4 4 0 Cell division protein ZapB CLZ PF16526.5 EMG47261.1 - 0.12 12.7 2.4 0.32 11.4 1.1 2.5 2 0 0 2 2 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 EMG47261.1 - 0.17 11.9 9.8 0.12 12.4 7.3 2.0 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 EMG47261.1 - 0.23 11.2 3.2 0.25 11.2 1.2 2.1 2 0 0 2 2 1 0 Septum formation initiator TMPIT PF07851.13 EMG47261.1 - 0.24 10.6 4.6 0.43 9.8 4.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein FlxA PF14282.6 EMG47261.1 - 0.25 11.3 2.3 6 6.9 0.1 3.0 2 0 0 2 2 2 0 FlxA-like protein Lipoprotein_20 PF13942.6 EMG47261.1 - 0.28 11.1 3.5 0.28 11.1 1.9 1.8 2 0 0 2 2 1 0 YfhG lipoprotein TRAF_BIRC3_bd PF16673.5 EMG47261.1 - 0.33 10.8 2.9 4.1 7.3 1.7 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF4795 PF16043.5 EMG47261.1 - 0.41 10.2 9.8 2.8 7.5 3.8 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4795) THOC7 PF05615.13 EMG47261.1 - 0.42 10.9 7.5 0.9 9.8 6.8 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 Tropomyosin_1 PF12718.7 EMG47261.1 - 0.62 10.2 14.5 0.57 10.3 6.6 3.2 3 0 0 3 3 3 0 Tropomyosin like DUF1664 PF07889.12 EMG47261.1 - 0.63 10.1 3.8 0.57 10.2 1.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) XhlA PF10779.9 EMG47261.1 - 0.65 10.2 3.4 3.1 8.1 3.4 2.2 1 0 0 1 1 1 0 Haemolysin XhlA Seryl_tRNA_N PF02403.22 EMG47261.1 - 6.3 7.1 14.6 0.37 11.0 6.6 3.0 3 2 1 4 4 3 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 EMG47261.1 - 8.3 6.7 10.6 1.2 9.4 2.4 3.3 3 1 1 4 4 4 0 ABC transporter C-terminal domain SEN1_N PF12726.7 EMG47262.1 - 3.4e-163 544.7 18.0 3.4e-163 544.7 18.0 1.6 2 0 0 2 2 2 1 SEN1 N terminal AAA_11 PF13086.6 EMG47262.1 - 8e-73 245.4 3.7 8e-73 245.4 3.7 2.1 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EMG47262.1 - 3.6e-65 219.3 0.0 1.2e-64 217.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMG47262.1 - 4.9e-09 36.7 0.0 3.7e-08 33.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMG47262.1 - 1.1e-08 35.1 0.0 4.1e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 EMG47262.1 - 8.5e-08 32.1 0.5 8.5e-08 32.1 0.5 4.1 2 2 0 3 3 3 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 EMG47262.1 - 7.7e-06 25.8 0.2 0.26 11.0 0.0 3.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EMG47262.1 - 0.011 15.7 0.7 0.12 12.3 0.1 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EMG47262.1 - 0.21 11.8 1.1 2.9 8.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain Fungal_trans_2 PF11951.8 EMG47263.1 - 3.4e-46 157.8 2.0 5.8e-46 157.0 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG47263.1 - 1.8e-08 34.3 10.0 3.2e-08 33.6 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M73 PF12389.8 EMG47263.1 - 0.059 13.2 0.6 0.12 12.2 0.6 1.4 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase COPIIcoated_ERV PF07970.12 EMG47264.1 - 3.2e-34 118.7 0.0 4.6e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EMG47264.1 - 5.4e-23 81.2 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IBR PF01485.21 EMG47265.1 - 1.4e-20 73.2 38.2 8.7e-11 41.9 3.2 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 EMG47265.1 - 5.3e-17 62.2 0.5 1.3e-16 61.0 0.5 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 EMG47265.1 - 2.3e-05 24.7 11.3 2.3e-05 24.7 11.3 3.8 3 1 0 3 3 3 1 Ring finger domain zf-ACC PF17848.1 EMG47265.1 - 3.1e-05 23.9 1.4 3.1e-05 23.9 1.4 4.0 3 0 0 3 3 3 2 Acetyl-coA carboxylase zinc finger domain zf-C3HC4 PF00097.25 EMG47265.1 - 4.1e-05 23.3 10.4 4.1e-05 23.3 10.4 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG47265.1 - 0.00058 19.8 10.8 0.00058 19.8 10.8 3.3 3 0 0 3 3 3 1 RING-type zinc-finger FYVE PF01363.21 EMG47265.1 - 1.8 8.8 31.2 0.59 10.3 9.6 3.5 3 0 0 3 3 3 0 FYVE zinc finger Zn_Tnp_IS91 PF14319.6 EMG47265.1 - 2.4 8.2 23.9 3.1 7.9 0.7 3.6 3 0 0 3 3 3 0 Transposase zinc-binding domain Pex24p PF06398.11 EMG47266.1 - 1.8e-105 353.0 0.7 2.2e-105 352.7 0.7 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Reticulon PF02453.17 EMG47266.1 - 0.023 14.6 2.7 0.46 10.4 2.6 2.4 1 1 0 1 1 1 0 Reticulon SIR4_SID PF16991.5 EMG47266.1 - 0.1 12.7 2.3 0.46 10.5 0.1 2.5 2 0 0 2 2 2 0 Sir4 SID domain Stm1_N PF09598.10 EMG47267.1 - 4.3e-07 30.7 15.8 4.3e-07 30.7 15.8 4.3 2 2 1 3 3 3 1 Stm1 Sec7 PF01369.20 EMG47268.1 - 2.7e-72 242.3 1.6 4.4e-72 241.6 0.6 1.9 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 EMG47268.1 - 8.4e-40 136.3 5.3 8.4e-40 136.3 5.3 3.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EMG47268.1 - 6.2e-34 115.7 4.7 1.7e-33 114.3 0.5 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DCB PF16213.5 EMG47268.1 - 4.7e-05 23.1 4.7 0.00054 19.7 0.4 2.7 2 0 0 2 2 2 2 Dimerisation and cyclophilin-binding domain of Mon2 His_kinase PF06580.13 EMG47268.1 - 0.065 13.6 0.1 0.52 10.7 0.0 2.7 2 0 0 2 2 2 0 Histidine kinase Mito_carr PF00153.27 EMG47270.1 - 1.4e-61 204.4 2.2 2.5e-22 78.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S19 PF00203.21 EMG47271.1 - 9.8e-33 111.9 0.1 1.3e-32 111.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 EMG47272.1 - 1.2e-26 93.1 12.7 1.4e-26 92.9 12.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein WRNPLPNID PF15017.6 EMG47272.1 - 0.084 13.8 2.8 0.17 12.8 2.8 1.5 1 1 0 1 1 1 0 Putative WW-binding domain and destruction box FTA4 PF13093.6 EMG47273.1 - 3.7e-32 111.9 13.3 4.6e-32 111.5 13.3 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Nup54 PF13874.6 EMG47273.1 - 0.45 10.6 7.7 0.21 11.7 3.5 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Mac PF12464.8 EMG47273.1 - 0.56 10.5 6.9 0.74 10.1 0.2 2.9 3 0 0 3 3 3 0 Maltose acetyltransferase Nucleoporin_FG PF13634.6 EMG47274.1 - 0.14 13.0 158.5 0.76 10.7 39.8 5.3 1 1 4 5 5 5 0 Nucleoporin FG repeat region RSN1_7TM PF02714.15 EMG47275.1 - 2.5e-82 276.3 25.0 2.5e-82 276.3 25.0 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EMG47275.1 - 1.2e-37 129.1 0.5 1.2e-37 129.1 0.5 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EMG47275.1 - 1.9e-33 116.1 0.1 3.4e-33 115.3 0.1 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF412 PF04217.13 EMG47275.1 - 0.0087 16.0 0.3 0.029 14.2 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF412 YMF19 PF02326.15 EMG47275.1 - 0.017 15.9 0.9 0.017 15.9 0.9 5.3 4 1 2 6 6 6 0 Plant ATP synthase F0 PBP1_TM PF14812.6 EMG47275.1 - 0.045 14.1 0.0 0.16 12.4 0.0 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4183 PF13799.6 EMG47276.1 - 0.37 10.6 1.5 0.63 9.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4183) DUF956 PF06115.11 EMG47277.1 - 0.087 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF956) BLACT_WH PF17778.1 EMG47277.1 - 0.12 12.4 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain zf-DNL PF05180.12 EMG47278.1 - 5.7e-27 93.4 1.1 9.5e-27 92.7 1.1 1.4 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 EMG47278.1 - 0.0024 17.9 0.2 0.0036 17.3 0.2 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Anti-TRAP PF15777.5 EMG47278.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc_ribbon_4 PF13717.6 EMG47278.1 - 0.15 12.0 1.9 0.32 10.9 0.0 2.3 3 0 0 3 3 3 0 zinc-ribbon domain CxC4 PF18717.1 EMG47278.1 - 0.25 11.2 4.7 0.27 11.1 0.1 2.2 1 1 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases Zn_Tnp_IS1595 PF12760.7 EMG47278.1 - 0.57 10.2 2.3 7.2 6.7 0.4 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain ATP11 PF06644.11 EMG47279.1 - 2.9e-74 250.3 6.0 1e-69 235.4 0.2 2.0 2 0 0 2 2 2 2 ATP11 protein DUF883 PF05957.13 EMG47279.1 - 0.19 12.4 0.8 35 5.1 0.0 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF438 PF04282.13 EMG47279.1 - 0.24 11.3 3.1 3.7 7.6 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF438) DUF4162 PF13732.6 EMG47279.1 - 0.35 11.6 6.6 1.2 9.9 1.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4162) YtxH PF12732.7 EMG47279.1 - 1 9.9 9.7 4.8e+02 1.4 9.7 2.5 1 1 0 1 1 1 0 YtxH-like protein Mre11_DNA_bind PF04152.14 EMG47280.1 - 8.3e-48 162.9 1.0 8.3e-48 162.9 1.0 1.7 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EMG47280.1 - 9.9e-10 39.2 0.7 2e-09 38.3 0.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Usp PF00582.26 EMG47280.1 - 0.02 15.4 0.2 14 6.2 0.1 3.3 3 0 0 3 3 3 0 Universal stress protein family HGTP_anticodon2 PF12745.7 EMG47281.1 - 5.6e-83 278.5 6.1 5.6e-83 278.5 6.1 2.7 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 EMG47281.1 - 4.6e-68 229.4 0.0 2.2e-36 125.6 0.0 4.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EMG47281.1 - 3.1e-38 131.6 0.0 6.1e-17 61.8 0.0 3.8 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EMG47281.1 - 2.1e-16 60.2 0.6 1.1e-15 57.9 0.6 2.4 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 EMG47281.1 - 1.3e-14 54.3 0.0 4.8e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 EMG47281.1 - 0.0015 18.0 0.0 0.11 11.8 0.0 3.1 3 0 0 3 3 3 1 Kinase-like UQ_con PF00179.26 EMG47281.1 - 0.018 14.7 0.2 0.088 12.5 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme OmpH PF03938.14 EMG47281.1 - 0.066 13.5 6.9 0.36 11.2 6.9 2.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Choline_kinase PF01633.20 EMG47282.1 - 1.9e-44 151.8 0.0 1.3e-43 149.1 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EMG47282.1 - 0.0026 17.7 0.0 0.0065 16.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sld5 PF05916.11 EMG47283.1 - 1e-12 48.4 0.3 1.5e-12 47.9 0.3 1.3 1 0 0 1 1 1 1 GINS complex protein Tuberin PF03542.16 EMG47283.1 - 0.045 12.9 0.2 0.058 12.5 0.2 1.1 1 0 0 1 1 1 0 Tuberin SUa-2TM PF18179.1 EMG47283.1 - 0.1 11.9 2.6 0.82 8.9 0.5 2.1 2 0 0 2 2 2 0 SMODS- and Ubiquitin system-associated 2TM effector domain AAA_34 PF13872.6 EMG47283.1 - 0.18 10.6 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Mur_ligase_C PF02875.21 EMG47284.1 - 5.1e-05 23.5 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 EMG47284.1 - 0.00021 21.4 1.5 0.0034 17.4 0.7 2.8 1 1 1 2 2 2 1 Mur ligase middle domain ArsC PF03960.15 EMG47284.1 - 0.0036 17.3 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 ArsC family TPR_1 PF00515.28 EMG47285.1 - 2.1e-20 71.6 18.1 0.00083 19.1 0.0 9.0 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 EMG47285.1 - 1.5e-19 68.4 31.8 0.0064 16.5 0.0 10.9 10 2 2 12 12 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 EMG47285.1 - 7.9e-15 55.2 3.3 2.8e-05 24.7 0.0 6.2 4 2 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMG47285.1 - 8.5e-13 47.8 20.8 4.3e-07 29.5 0.0 6.8 6 2 1 7 7 7 3 TPR repeat TPR_19 PF14559.6 EMG47285.1 - 1.7e-12 47.6 7.2 0.00082 19.8 0.2 5.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMG47285.1 - 1.7e-10 40.3 26.0 0.15 12.3 0.0 9.8 10 1 1 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMG47285.1 - 2.7e-09 36.8 6.8 0.036 14.4 0.1 7.5 6 3 2 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMG47285.1 - 1.8e-08 34.6 14.4 0.13 12.6 0.1 7.1 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EMG47285.1 - 1.5e-07 31.6 9.8 0.31 12.0 0.1 7.5 6 3 4 10 10 7 2 Tetratricopeptide repeat SpoIIIAH PF12685.7 EMG47285.1 - 1.2e-05 25.2 7.3 1.2e-05 25.2 7.3 2.3 2 0 0 2 2 2 1 SpoIIIAH-like protein TPR_9 PF13371.6 EMG47285.1 - 3.9e-05 23.7 0.0 0.26 11.5 0.1 4.0 3 1 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG47285.1 - 6e-05 23.2 13.2 1.1 9.5 0.0 5.3 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 EMG47285.1 - 0.00011 22.0 11.0 0.055 13.2 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 EMG47285.1 - 0.0012 18.7 5.9 0.12 12.4 0.1 4.7 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EMG47285.1 - 0.0048 16.2 2.5 1.8 7.7 0.0 3.1 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF4810 PF16068.5 EMG47285.1 - 0.012 16.1 7.1 0.82 10.3 0.0 4.1 2 1 2 4 4 2 0 Domain of unknown function (DUF4810) HrpB1_HrpK PF09613.10 EMG47285.1 - 0.013 15.2 0.1 0.19 11.3 0.3 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) HemX PF04375.14 EMG47285.1 - 0.021 14.1 0.3 0.046 13.0 0.3 1.5 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TPR_MalT PF17874.1 EMG47285.1 - 0.049 13.0 1.3 2.5 7.4 0.2 2.8 1 1 0 2 2 2 0 MalT-like TPR region DUF2140 PF09911.9 EMG47285.1 - 0.12 11.9 1.5 7.9 6.0 0.3 3.5 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2140) TPR_6 PF13174.6 EMG47285.1 - 0.17 12.6 15.2 1.3 9.8 0.0 6.7 9 0 0 9 9 5 0 Tetratricopeptide repeat PTS_IIA PF02255.16 EMG47285.1 - 0.24 11.5 1.9 71 3.5 0.0 4.3 3 1 1 4 4 4 0 PTS system, Lactose/Cellobiose specific IIA subunit Ndc1_Nup PF09531.10 EMG47285.1 - 0.59 8.8 2.8 0.85 8.2 2.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRP14 PF15459.6 EMG47285.1 - 3.7 8.2 12.1 5.7 7.6 8.1 2.9 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Presenilin PF01080.17 EMG47285.1 - 8.7 5.0 6.2 12 4.5 6.2 1.2 1 0 0 1 1 1 0 Presenilin ATP_bind_1 PF03029.17 EMG47286.1 - 7.5e-81 271.5 0.5 7.5e-81 271.5 0.5 1.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EMG47286.1 - 3.5e-07 30.0 3.5 2e-06 27.5 1.2 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EMG47286.1 - 2.3e-06 27.5 0.8 1e-05 25.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 EMG47286.1 - 0.00012 21.1 0.2 0.33 9.9 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EMG47286.1 - 0.00017 21.8 0.0 0.00039 20.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EMG47286.1 - 0.00023 21.2 0.2 0.013 15.6 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMG47286.1 - 0.00023 21.1 0.0 0.95 9.3 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EMG47286.1 - 0.00036 20.8 0.3 0.0024 18.2 0.0 2.5 4 0 0 4 4 3 1 AAA domain PduV-EutP PF10662.9 EMG47286.1 - 0.001 18.8 0.0 0.12 12.1 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 EMG47286.1 - 0.0013 18.4 0.0 0.023 14.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain FeoB_N PF02421.18 EMG47286.1 - 0.0017 17.9 0.0 0.052 13.1 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B NACHT PF05729.12 EMG47286.1 - 0.0019 18.2 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arf PF00025.21 EMG47286.1 - 0.0038 16.7 0.2 0.42 10.1 0.0 3.1 2 2 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 EMG47286.1 - 0.0043 17.2 0.1 0.66 10.2 0.0 2.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EMG47286.1 - 0.0059 16.2 0.4 0.033 13.8 0.4 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EMG47286.1 - 0.0063 16.9 0.0 0.017 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EMG47286.1 - 0.0094 16.5 2.8 0.036 14.6 0.0 2.9 3 1 1 4 4 4 1 AAA domain CLP1_P PF16575.5 EMG47286.1 - 0.011 15.6 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 EMG47286.1 - 0.015 14.9 0.0 0.045 13.3 0.0 1.8 2 0 0 2 2 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 EMG47286.1 - 0.032 13.5 1.4 0.28 10.4 1.4 2.2 1 1 0 1 1 1 0 KAP family P-loop domain DUF87 PF01935.17 EMG47286.1 - 0.047 13.8 0.4 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Thioredoxin_7 PF13899.6 EMG47286.1 - 0.062 13.5 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like Viral_helicase1 PF01443.18 EMG47286.1 - 0.068 12.9 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EMG47286.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EMG47286.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 EMG47286.1 - 0.12 12.3 0.1 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 NTPase CbiA PF01656.23 EMG47286.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 EMG47286.1 - 0.15 11.7 2.2 0.26 11.0 0.0 2.4 3 0 0 3 3 2 0 Thymidylate kinase ATP-synt_E PF05680.12 EMG47286.1 - 0.15 12.4 3.0 0.42 11.0 3.0 1.8 1 0 0 1 1 1 0 ATP synthase E chain SRPRB PF09439.10 EMG47286.1 - 0.71 9.3 4.2 1.2 8.5 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Glyco_hydro_125 PF06824.11 EMG47287.1 - 9.3e-153 509.0 0.0 1.1e-152 508.7 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) PAP2 PF01569.21 EMG47288.1 - 9e-25 87.0 1.3 9e-25 87.0 1.3 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EMG47288.1 - 0.0055 16.4 10.4 0.011 15.4 7.8 2.6 1 1 1 2 2 2 2 PAP2 superfamily DUF2298 PF10060.9 EMG47288.1 - 0.0059 15.4 0.8 0.0084 14.9 0.8 1.2 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) Colicin_V PF02674.16 EMG47288.1 - 0.075 13.0 8.8 0.33 10.9 1.1 2.9 2 1 0 2 2 2 0 Colicin V production protein 7TMR-DISM_7TM PF07695.11 EMG47288.1 - 0.39 10.6 11.3 4.5 7.1 5.3 2.6 2 1 0 2 2 2 0 7TM diverse intracellular signalling IspA PF04279.15 EMG47288.1 - 2.1 8.5 8.6 0.38 10.9 0.6 2.4 2 1 1 3 3 3 0 Intracellular septation protein A SPC12 PF06645.13 EMG47288.1 - 7.1 6.8 11.6 1.5 9.0 0.8 3.3 3 1 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) AAA PF00004.29 EMG47289.1 - 3.5e-58 195.7 0.0 8.5e-43 145.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EMG47289.1 - 1.2e-24 86.5 0.0 3.1e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 EMG47289.1 - 8.7e-12 45.7 0.9 4.7e-05 23.8 0.0 3.7 2 2 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 EMG47289.1 - 6.9e-10 38.6 0.0 7.6e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_14 PF13173.6 EMG47289.1 - 2.7e-08 33.9 1.4 0.0035 17.4 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EMG47289.1 - 1.3e-07 32.0 6.2 0.0023 18.2 2.4 4.2 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.14 EMG47289.1 - 1.1e-05 25.6 0.0 0.016 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EMG47289.1 - 1.9e-05 25.0 2.2 0.044 14.2 0.3 3.2 3 0 0 3 3 2 2 RNA helicase IstB_IS21 PF01695.17 EMG47289.1 - 2.4e-05 24.1 0.1 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 EMG47289.1 - 3e-05 24.0 3.9 0.027 14.4 0.6 3.7 3 1 0 3 3 3 2 NACHT domain DUF2075 PF09848.9 EMG47289.1 - 0.00013 21.3 0.1 0.065 12.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EMG47289.1 - 0.00015 21.4 1.8 0.45 10.1 0.1 3.8 2 2 1 4 4 4 1 AAA domain ABC_tran PF00005.27 EMG47289.1 - 0.00024 21.6 10.5 0.013 16.0 2.7 3.8 4 1 0 4 4 3 2 ABC transporter AAA_5 PF07728.14 EMG47289.1 - 0.00024 21.1 0.1 0.99 9.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EMG47289.1 - 0.00032 20.4 0.1 0.12 12.0 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 EMG47289.1 - 0.00039 21.0 2.7 0.33 11.5 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMG47289.1 - 0.00055 20.1 0.0 0.18 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EMG47289.1 - 0.00058 19.6 0.3 0.39 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EMG47289.1 - 0.00077 19.0 0.0 0.092 12.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase PF06745.13 EMG47289.1 - 0.0016 17.8 0.0 1.7 7.9 0.0 2.8 2 0 0 2 2 2 2 KaiC RuvB_N PF05496.12 EMG47289.1 - 0.0016 18.2 0.0 0.018 14.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 EMG47289.1 - 0.0028 18.1 0.0 1.9 8.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EMG47289.1 - 0.0055 15.9 0.5 1.9 7.6 0.1 2.7 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 EMG47289.1 - 0.0059 16.6 8.6 0.0094 15.9 0.4 3.7 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EMG47289.1 - 0.0061 16.3 0.0 0.06 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EMG47289.1 - 0.0069 15.6 0.3 0.29 10.3 0.0 2.7 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_29 PF13555.6 EMG47289.1 - 0.016 14.9 0.1 0.32 10.8 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EMG47289.1 - 0.024 14.0 0.1 0.57 9.5 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EMG47289.1 - 0.028 13.7 0.1 4.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 EMG47289.1 - 0.04 13.9 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EMG47289.1 - 1.1 9.2 5.3 1.1 9.2 0.1 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF3767 PF12597.8 EMG47291.1 - 4e-36 122.9 0.1 5.2e-36 122.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) EMC3_TMCO1 PF01956.16 EMG47292.1 - 5.3e-52 176.0 1.7 6.7e-52 175.6 0.0 1.7 1 1 1 2 2 2 1 Integral membrane protein EMC3/TMCO1-like AAA PF00004.29 EMG47293.1 - 1e-18 68.0 0.5 8.3e-16 58.6 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EMG47293.1 - 3e-14 53.1 0.1 8.8e-13 48.4 0.1 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 EMG47293.1 - 1.5e-13 51.0 0.7 3.2e-13 49.9 0.7 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 EMG47293.1 - 3e-07 30.6 0.0 9.9e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EMG47293.1 - 2.1e-06 28.0 1.1 8.3e-05 22.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMG47293.1 - 1.6e-05 25.4 0.1 0.00045 20.6 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_11 PF13086.6 EMG47293.1 - 1.8e-05 24.7 0.1 3.3e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EMG47293.1 - 4.9e-05 23.1 0.0 0.00014 21.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EMG47293.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EMG47293.1 - 0.00024 21.2 0.1 0.0021 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EMG47293.1 - 0.00037 19.9 0.0 0.008 15.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 EMG47293.1 - 0.0015 18.5 0.3 0.01 15.8 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 EMG47293.1 - 0.0027 17.5 0.0 0.0068 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMG47293.1 - 0.0027 17.4 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMG47293.1 - 0.0035 17.9 0.6 0.008 16.7 0.6 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EMG47293.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 EMG47293.1 - 0.0062 16.5 0.0 0.026 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EMG47293.1 - 0.0076 16.6 0.0 0.043 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EMG47293.1 - 0.02 14.2 0.0 0.054 12.7 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 EMG47293.1 - 0.024 15.2 0.3 2.9 8.4 0.0 2.6 2 1 0 2 2 2 0 ABC transporter AAA_assoc_2 PF16193.5 EMG47293.1 - 0.028 14.7 0.0 0.091 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_18 PF13238.6 EMG47293.1 - 0.029 14.9 0.1 0.14 12.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 EMG47293.1 - 0.035 14.3 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EMG47293.1 - 0.044 13.7 0.1 0.61 10.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMG47293.1 - 0.064 13.7 0.0 0.16 12.4 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EMG47293.1 - 0.14 12.3 0.0 0.44 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain DEAD PF00270.29 EMG47293.1 - 0.15 11.8 0.5 2.6 7.8 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase DSPc PF00782.20 EMG47295.1 - 4.1e-28 97.8 1.2 3e-19 69.1 0.1 4.0 3 1 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMG47295.1 - 3e-05 23.7 0.1 8.6e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MFS_1 PF07690.16 EMG47296.1 - 3.4e-20 72.3 15.2 3.4e-20 72.3 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG47296.1 - 4.6e-15 55.4 18.9 6.9e-15 54.8 18.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3453 PF11935.8 EMG47297.1 - 3.3e-44 151.2 2.8 1e-43 149.6 2.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) PX PF00787.24 EMG47297.1 - 8.1e-22 77.4 0.1 3.1e-21 75.5 0.1 2.1 1 0 0 1 1 1 1 PX domain DUF3342 PF11822.8 EMG47297.1 - 0.13 12.5 2.6 0.28 11.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) BTB_2 PF02214.22 EMG47298.1 - 0.037 14.4 0.0 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain COPI_C PF06957.11 EMG47298.1 - 0.19 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Homeobox_KN PF05920.11 EMG47300.1 - 7.1e-19 67.4 0.9 1.5e-18 66.4 0.9 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EMG47300.1 - 2.8e-05 23.9 0.7 5.9e-05 22.8 0.7 1.6 1 0 0 1 1 1 1 Homeodomain TFIIA PF03153.13 EMG47300.1 - 0.16 12.0 12.6 0.2 11.6 12.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF_A PF03178.15 EMG47302.1 - 0.00017 21.1 0.1 0.0095 15.3 0.0 2.9 2 1 1 3 3 3 1 CPSF A subunit region Lactonase PF10282.9 EMG47302.1 - 0.038 13.2 0.0 0.18 11.1 0.0 2.0 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller WD40 PF00400.32 EMG47302.1 - 0.11 13.4 0.0 93 4.1 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat ABC_membrane PF00664.23 EMG47303.1 - 1.1e-85 287.6 29.4 1.4e-46 159.3 14.2 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMG47303.1 - 5.6e-47 159.7 3.2 2.1e-27 96.3 0.3 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EMG47303.1 - 7.7e-11 41.9 4.5 6.3e-07 29.0 0.9 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EMG47303.1 - 4.5e-06 26.7 0.3 0.17 11.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EMG47303.1 - 0.00036 20.2 0.5 0.79 9.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain UPF0093 PF03653.13 EMG47303.1 - 0.00038 20.7 0.2 0.0018 18.5 0.2 2.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) RsgA_GTPase PF03193.16 EMG47303.1 - 0.0011 18.9 0.8 0.53 10.2 0.2 2.7 2 1 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EMG47303.1 - 0.0086 16.6 10.7 0.27 11.7 1.0 3.4 4 1 0 4 4 3 2 AAA domain AAA_21 PF13304.6 EMG47303.1 - 0.0095 15.8 1.8 3.4 7.4 0.0 3.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EMG47303.1 - 0.012 15.3 1.0 2.6 7.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMG47303.1 - 0.017 15.5 0.1 0.52 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 EMG47303.1 - 0.046 13.4 0.5 0.67 9.7 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein Dynamin_N PF00350.23 EMG47303.1 - 0.047 13.7 1.9 2.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Dynamin family DUF87 PF01935.17 EMG47303.1 - 0.05 13.7 2.4 0.66 10.0 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain DUF1691 PF07950.11 EMG47303.1 - 0.072 13.8 0.1 0.22 12.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Sigma54_activat PF00158.26 EMG47303.1 - 0.087 12.5 0.1 0.98 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PIRT PF15099.6 EMG47303.1 - 0.11 12.1 0.5 0.92 9.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Zeta_toxin PF06414.12 EMG47303.1 - 0.15 11.4 0.2 17 4.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 EMG47303.1 - 0.15 11.6 0.5 2.8 7.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EMG47303.1 - 0.2 11.9 2.2 22 5.3 0.6 3.2 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EMG47303.1 - 0.38 10.4 9.8 2.2 7.9 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain MFS_1 PF07690.16 EMG47304.1 - 2.5e-20 72.7 22.3 3.5e-20 72.2 22.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 EMG47304.1 - 0.013 13.5 0.0 0.022 12.7 0.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RIC3 PF15361.6 EMG47304.1 - 0.12 12.8 0.1 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF485 PF04341.12 EMG47304.1 - 0.29 11.1 12.2 18 5.4 0.4 3.7 2 1 1 3 3 3 0 Protein of unknown function, DUF485 Avl9 PF09794.9 EMG47305.1 - 2e-123 411.9 7.4 2.7e-123 411.4 7.4 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EMG47305.1 - 1.8e-09 37.6 1.6 6.3e-09 35.8 1.6 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EMG47305.1 - 0.00023 21.1 2.9 0.066 13.2 0.2 2.6 1 1 1 2 2 2 2 Stabilization of polarity axis DENN PF02141.21 EMG47305.1 - 0.0033 17.4 1.7 0.0081 16.1 1.7 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain OAD_gamma PF04277.13 EMG47306.1 - 0.001 19.6 2.8 0.0016 19.0 2.8 1.5 1 1 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain DUF5385 PF17359.2 EMG47306.1 - 0.0042 16.7 0.0 0.0054 16.3 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5385) SARAF PF06682.12 EMG47306.1 - 0.042 13.5 0.0 0.046 13.4 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CreD PF06123.12 EMG47306.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 Inner membrane protein CreD LSM PF01423.22 EMG47307.1 - 5.1e-16 58.1 0.0 7.8e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain ANAPC_CDC26 PF10471.9 EMG47307.1 - 1.4 9.8 10.5 2.3 9.1 10.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Zip PF02535.22 EMG47307.1 - 4.5 6.4 4.2 5.5 6.1 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EMG47307.1 - 5.4 5.7 6.8 6.7 5.4 6.8 1.1 1 0 0 1 1 1 0 Presenilin PIP5K PF01504.18 EMG47308.1 - 2.1e-64 217.4 5.4 5.4e-64 216.1 5.4 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase GRP PF07172.11 EMG47309.1 - 0.00023 21.8 0.7 1.1 10.0 0.0 2.3 2 0 0 2 2 2 1 Glycine rich protein family BatA PF07584.11 EMG47309.1 - 0.00085 19.6 1.7 0.0012 19.1 1.7 1.1 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal BatD PF13584.6 EMG47309.1 - 0.035 12.9 0.1 0.04 12.7 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance Glucos_trans_II PF14264.6 EMG47309.1 - 0.056 12.8 0.2 0.07 12.5 0.2 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII WBP-1 PF11669.8 EMG47309.1 - 0.059 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 SARAF PF06682.12 EMG47309.1 - 0.065 12.9 2.6 0.1 12.2 2.6 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis FAM209 PF15206.6 EMG47309.1 - 0.093 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 FAM209 family DUF4381 PF14316.6 EMG47309.1 - 0.12 12.6 0.2 0.19 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) NT-C2 PF10358.9 EMG47311.1 - 3.5e-36 124.1 7.0 1.7e-35 121.9 7.0 2.0 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF4611 PF15387.6 EMG47312.1 - 0.028 14.6 0.1 0.071 13.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) IF-2B PF01008.17 EMG47313.1 - 1e-45 156.1 0.0 1.4e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family UPF0052 PF01933.18 EMG47314.1 - 4.4e-56 190.3 0.0 6.8e-56 189.7 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 WD40 PF00400.32 EMG47315.1 - 1.8e-44 148.8 19.7 6.8e-08 33.1 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG47315.1 - 5.2e-11 42.7 0.6 0.01 16.1 0.0 4.8 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMG47315.1 - 3.3e-06 26.0 9.2 0.009 14.7 0.0 4.8 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EMG47315.1 - 1.8e-05 23.9 1.2 0.13 11.2 0.0 4.2 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EMG47315.1 - 0.0036 17.2 0.0 2.8 8.0 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat KOW PF00467.29 EMG47315.1 - 0.084 12.9 0.1 0.65 10.0 0.0 2.4 2 1 0 2 2 2 0 KOW motif IKI3 PF04762.12 EMG47315.1 - 0.13 10.2 0.0 0.31 9.0 0.0 1.5 1 1 0 1 1 1 0 IKI3 family WD40 PF00400.32 EMG47316.1 - 6.9e-09 36.2 4.3 0.006 17.4 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat FKBP_C PF00254.28 EMG47317.1 - 2.8e-31 107.7 0.0 3.4e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Foie-gras_1 PF11817.8 EMG47318.1 - 1.2e-20 74.3 0.0 6.1e-14 52.2 0.0 2.3 1 1 1 2 2 2 2 Foie gras liver health family 1 PUB PF09409.10 EMG47318.1 - 0.0064 16.4 0.1 0.022 14.7 0.1 1.9 1 0 0 1 1 1 1 PUB domain TBCC PF07986.12 EMG47319.1 - 1.1e-12 47.7 1.6 2.4e-12 46.7 1.6 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C FeS_assembly_P PF01883.19 EMG47319.1 - 1.7e-09 37.7 0.1 3.9e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein AMP-binding PF00501.28 EMG47320.1 - 1.8e-65 221.2 0.0 4.4e-63 213.4 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme RT_RNaseH_2 PF17919.1 EMG47321.1 - 2.3e-20 72.5 0.2 6.9e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EMG47321.1 - 5.7e-19 68.3 0.0 2e-18 66.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EMG47321.1 - 8e-19 68.0 0.0 2.6e-18 66.4 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EMG47321.1 - 5.4e-15 55.6 0.0 1.3e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 EMG47321.1 - 5.1e-09 36.1 1.1 2e-08 34.2 0.4 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain zf-CCHC PF00098.23 EMG47321.1 - 0.085 13.0 1.4 0.17 12.0 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle rve_3 PF13683.6 EMG47321.1 - 0.14 12.0 0.0 0.51 10.1 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain MMM1 PF10296.9 EMG47322.1 - 1.9e-06 27.2 10.0 1.5e-05 24.2 0.2 2.8 3 1 0 3 3 3 2 Maintenance of mitochondrial morphology protein 1 Mpp10 PF04006.12 EMG47322.1 - 0.00011 20.8 12.0 0.00011 20.8 12.0 2.1 2 0 0 2 2 2 2 Mpp10 protein SDA1 PF05285.12 EMG47322.1 - 0.00054 19.5 17.7 0.00054 19.5 17.7 2.1 2 0 0 2 2 2 2 SDA1 BUD22 PF09073.10 EMG47322.1 - 0.0072 15.7 15.6 0.0072 15.7 15.6 2.2 2 0 0 2 2 2 2 BUD22 CDC45 PF02724.14 EMG47322.1 - 0.048 12.0 21.3 0.0065 14.8 10.2 2.2 2 0 0 2 2 2 0 CDC45-like protein SAPS PF04499.15 EMG47322.1 - 0.39 9.5 9.9 0.031 13.1 4.3 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 EMG47322.1 - 1 9.2 11.4 0.55 10.0 5.6 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein CNDH2_C PF16858.5 EMG47322.1 - 1.2 9.0 13.2 0.066 13.1 6.1 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4746 PF15928.5 EMG47322.1 - 1.8 7.9 18.8 1.3 8.4 8.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) PPP4R2 PF09184.11 EMG47322.1 - 4.1 6.9 36.3 1.3 8.5 24.6 2.3 2 0 0 2 2 2 0 PPP4R2 DcpS PF05652.12 EMG47323.1 - 3.1e-31 108.3 0.4 4.1e-31 107.9 0.4 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EMG47323.1 - 7.2e-09 36.1 0.1 4.7e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DEAD PF00270.29 EMG47324.1 - 1.5e-43 148.6 0.2 3.6e-43 147.4 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EMG47324.1 - 7.7e-21 74.1 0.0 8.7e-20 70.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EMG47324.1 - 5.9e-19 68.5 0.0 3.1e-18 66.1 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG47324.1 - 6.4e-07 29.5 0.2 1.6e-06 28.2 0.2 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SIR2_2 PF13289.6 EMG47324.1 - 0.12 12.5 0.0 0.61 10.2 0.0 2.2 3 0 0 3 3 3 0 SIR2-like domain Sin_N PF04801.13 EMG47325.1 - 2.7e-21 76.3 0.6 3.3e-21 76.0 0.6 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Poty_PP PF08440.10 EMG47326.1 - 0.01 15.0 0.2 0.039 13.0 0.1 1.9 2 0 0 2 2 2 0 Potyviridae polyprotein LigB PF02900.18 EMG47327.1 - 4.5e-30 104.6 0.0 5.9e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.16 EMG47328.1 - 3.5e-11 42.8 0.0 4.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PTS-HPr PF00381.19 EMG47328.1 - 0.064 13.5 0.1 0.097 12.9 0.1 1.3 1 0 0 1 1 1 0 PTS HPr component phosphorylation site GFO_IDH_MocA PF01408.22 EMG47329.1 - 4.1e-20 72.8 0.1 6.4e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMG47329.1 - 1.4e-13 50.8 0.0 3.1e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.19 EMG47329.1 - 0.14 12.8 0.0 0.32 11.7 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Plus-3 PF03126.18 EMG47331.1 - 5.6e-26 91.2 1.1 1.5e-25 89.9 0.0 2.3 2 0 0 2 2 2 1 Plus-3 domain RPAP3_C PF13877.6 EMG47331.1 - 0.02 15.4 0.8 0.061 13.9 0.3 2.1 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 Ribosomal_S28e PF01200.18 EMG47332.1 - 9.6e-33 112.0 1.7 1.1e-32 111.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Cyt-b5 PF00173.28 EMG47333.1 - 1.4e-25 89.2 0.3 2.1e-25 88.6 0.3 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.22 EMG47334.1 - 1.2e-17 63.5 0.1 2.4e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 EMG47334.1 - 0.013 13.8 12.0 0.013 13.8 12.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Mad3_BUB1_I_2 PF17014.5 EMG47334.1 - 0.041 14.0 2.2 0.069 13.3 1.3 1.9 1 1 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Nop14 PF04147.12 EMG47334.1 - 0.08 11.1 24.5 0.14 10.3 24.5 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EMG47334.1 - 1.7 7.1 13.0 2.2 6.7 13.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF913 PF06025.12 EMG47334.1 - 1.8 7.5 8.4 2.4 7.0 8.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ctf8 PF09696.10 EMG47334.1 - 2.7 8.3 8.7 13 6.1 8.7 2.3 1 1 0 1 1 1 0 Ctf8 Maf PF02545.14 EMG47335.1 - 6.4e-34 117.2 0.0 7.3e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DNA_pol3_a_NI PF14480.6 EMG47335.1 - 0.06 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I Syja_N PF02383.18 EMG47336.1 - 1.3e-75 254.7 1.0 2.2e-75 253.9 1.0 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EMG47336.1 - 3.7e-10 39.7 0.1 1.1e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Nop16 PF09420.10 EMG47338.1 - 3.2 7.7 6.2 5 7.1 0.6 2.4 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 Pkinase PF00069.25 EMG47339.1 - 5e-60 203.1 0.0 8e-38 130.3 0.1 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMG47339.1 - 4.5e-30 104.8 0.1 4.3e-22 78.6 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EMG47339.1 - 1.1e-06 28.2 0.7 6.3e-05 22.4 0.0 3.0 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 EMG47339.1 - 0.00011 21.6 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMG47339.1 - 0.00019 21.5 0.1 0.004 17.1 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EMG47339.1 - 0.003 16.6 6.0 0.003 16.6 6.0 3.5 2 2 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EMG47339.1 - 0.0098 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 PAS_9 PF13426.7 EMG47339.1 - 0.022 15.0 0.1 0.093 13.0 0.1 2.1 1 0 0 1 1 1 0 PAS domain RIO1 PF01163.22 EMG47339.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family bZIP_2 PF07716.15 EMG47340.1 - 3.2e-12 46.3 10.1 3.2e-12 46.3 10.1 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EMG47340.1 - 0.0007 19.6 12.4 0.0007 19.6 12.4 2.0 1 1 0 2 2 2 1 bZIP transcription factor TFIIA PF03153.13 EMG47340.1 - 0.0065 16.5 19.7 0.0074 16.3 19.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FlaC_arch PF05377.11 EMG47340.1 - 0.16 12.3 2.9 0.35 11.3 2.9 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TMEM51 PF15345.6 EMG47340.1 - 3.4 7.4 14.7 4.5 7.1 14.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 TatD_DNase PF01026.21 EMG47341.1 - 1.8e-41 142.2 0.0 6.2e-41 140.5 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase Excalibur PF05901.11 EMG47341.1 - 0.15 12.7 0.2 0.42 11.3 0.2 1.8 1 0 0 1 1 1 0 Excalibur calcium-binding domain LRR_4 PF12799.7 EMG47342.1 - 7.4e-08 32.6 26.4 1.4 9.4 6.5 7.7 5 3 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG47342.1 - 0.0037 17.0 21.1 0.053 13.3 7.9 6.0 5 1 1 6 6 6 1 Leucine rich repeat FNIP PF05725.12 EMG47342.1 - 0.0039 17.3 23.5 3.4 7.9 0.0 7.3 7 1 1 8 8 8 4 FNIP Repeat F-box PF00646.33 EMG47342.1 - 0.051 13.5 0.3 0.21 11.5 0.3 2.1 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EMG47342.1 - 0.21 11.5 0.9 0.61 10.0 0.9 1.8 1 0 0 1 1 1 0 F-box-like LRR_2 PF07723.13 EMG47342.1 - 0.27 12.0 1.7 2.6 8.8 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat CBM_21 PF03370.13 EMG47343.1 - 1.3e-27 96.2 2.5 1.3e-27 96.2 2.5 2.1 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EMG47343.1 - 1.4e-09 38.4 0.6 1.4e-09 38.4 0.6 2.1 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) Thg1 PF04446.12 EMG47344.1 - 3.1e-49 166.2 0.6 5.6e-49 165.3 0.6 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EMG47344.1 - 3.1e-49 166.2 5.4 4.2e-49 165.7 5.4 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain tRNA-synt_1c PF00749.21 EMG47345.1 - 8e-113 376.5 0.1 2.2e-112 375.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 EMG47345.1 - 4e-46 157.0 1.1 9.5e-46 155.8 0.2 2.0 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 EMG47345.1 - 2.5e-28 99.1 0.1 1.2e-26 93.6 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 EMG47345.1 - 1.1e-11 45.4 3.9 2.9e-11 44.1 3.9 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PRK PF00485.18 EMG47346.1 - 2.1e-06 27.6 0.0 7.9e-06 25.7 0.0 1.8 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 EMG47346.1 - 8.1e-06 25.2 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EMG47346.1 - 3e-05 24.2 0.1 0.0006 20.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EMG47346.1 - 0.00014 22.3 0.3 0.0031 17.9 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMG47346.1 - 0.00022 21.8 0.0 0.00044 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EMG47346.1 - 0.00086 18.8 0.1 0.0019 17.7 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 EMG47346.1 - 0.0051 16.5 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 Thymidylate kinase NB-ARC PF00931.22 EMG47346.1 - 0.0061 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 EMG47346.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.15 EMG47346.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 EMG47346.1 - 0.024 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EMG47346.1 - 0.026 14.1 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.15 EMG47346.1 - 0.035 14.1 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MeaB PF03308.16 EMG47346.1 - 0.046 12.7 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 EMG47346.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 EMG47346.1 - 0.058 13.7 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EMG47346.1 - 0.067 13.1 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 EMG47346.1 - 0.067 13.1 0.0 0.14 12.0 0.0 1.5 2 0 0 2 2 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 EMG47346.1 - 0.082 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EMG47346.1 - 0.097 13.1 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DnaB_C PF03796.15 EMG47346.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NACHT PF05729.12 EMG47346.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 EMG47346.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_pol_Rpb2_6 PF00562.28 EMG47347.1 - 3e-113 378.8 0.0 8.5e-113 377.3 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EMG47347.1 - 7.6e-39 133.3 0.1 1.2e-38 132.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EMG47347.1 - 9.7e-31 106.9 0.0 2.3e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 EMG47347.1 - 2.9e-28 97.8 0.0 6.1e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 EMG47347.1 - 2.7e-24 84.9 0.0 5.5e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EMG47347.1 - 5.9e-16 58.6 0.0 7.6e-15 55.1 0.0 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 tRNA-synt_1c PF00749.21 EMG47348.1 - 1.9e-114 381.8 0.0 2.6e-114 381.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EMG47348.1 - 3.2e-40 137.9 0.7 8.9e-40 136.4 0.7 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 EMG47348.1 - 1.8e-20 73.1 1.4 1.8e-20 73.1 1.4 2.9 3 0 0 3 3 3 1 Glutamate--tRNA ligase N-terminal domain GST_C PF00043.25 EMG47348.1 - 7.1e-05 22.9 0.5 0.00029 21.0 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMG47348.1 - 0.00083 19.3 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMG47348.1 - 0.074 13.2 0.1 0.24 11.6 0.1 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RRM_4 PF10598.9 EMG47348.1 - 0.082 13.3 0.1 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 DUF155 PF02582.14 EMG47349.1 - 2e-56 190.9 0.6 2e-56 190.9 0.6 2.0 3 0 0 3 3 3 1 Uncharacterised ACR, YagE family COG1723 TFIIA PF03153.13 EMG47349.1 - 0.74 9.7 16.0 1.7 8.6 16.0 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spem1 PF15670.5 EMG47349.1 - 1.5 8.3 11.5 0.93 9.0 9.3 1.8 1 1 0 1 1 1 0 Spermatid maturation protein 1 PIN_4 PF13638.6 EMG47350.1 - 6.1e-30 104.2 0.4 1.5e-29 103.0 0.1 1.8 2 0 0 2 2 2 1 PIN domain PIN_9 PF18477.1 EMG47350.1 - 0.0022 18.3 0.0 0.035 14.4 0.0 2.4 2 0 0 2 2 2 1 PIN like domain PIN_12 PF16289.5 EMG47350.1 - 0.012 16.1 6.8 0.075 13.5 0.0 3.2 3 1 0 4 4 4 0 PIN domain XLF PF09302.11 EMG47351.1 - 3.4e-07 30.6 0.3 3.4e-07 30.6 0.3 2.4 2 2 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Frtz PF11768.8 EMG47351.1 - 0.0068 14.8 0.1 0.009 14.4 0.1 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF960 PF06124.11 EMG47351.1 - 0.38 11.4 6.7 1.3 9.7 1.0 2.8 2 1 1 3 3 3 0 Staphylococcal protein of unknown function (DUF960) rve_2 PF13333.6 EMG47351.1 - 1 9.6 6.0 1.5 9.1 1.6 2.7 2 0 0 2 2 2 0 Integrase core domain SUR7 PF06687.12 EMG47352.1 - 4.1e-37 127.9 11.2 5e-37 127.6 11.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4064 PF13273.6 EMG47352.1 - 0.27 11.5 9.5 1.5 9.2 2.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4491 PF14898.6 EMG47352.1 - 2.2 8.8 10.3 0.29 11.6 1.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4491) DUF4451 PF14616.6 EMG47353.1 - 9.9e-25 87.1 1.8 2.2e-24 86.0 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) AA_permease PF00324.21 EMG47354.1 - 8.5e-95 318.1 39.8 1.1e-94 317.7 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG47354.1 - 3e-22 79.1 41.4 3.6e-22 78.8 40.9 1.3 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 EMG47355.1 - 1.2e-44 152.6 0.1 2.1e-44 151.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG47355.1 - 6.2e-27 94.5 0.1 1.6e-26 93.2 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG47355.1 - 4.6e-09 36.0 0.0 3e-08 33.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EMG47355.1 - 7.2e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EMG47355.1 - 0.0025 17.4 0.1 0.0043 16.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EMG47355.1 - 0.0038 17.2 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EMG47355.1 - 0.016 14.9 0.2 0.039 13.6 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Arm-DNA-bind_2 PF12167.8 EMG47355.1 - 0.034 14.0 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 Arm DNA-binding domain Pkinase_fungal PF17667.1 EMG47355.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 EMG47356.1 - 8.3e-13 48.0 0.0 8.8e-11 41.5 0.0 3.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.29 EMG47357.1 - 2.6e-15 56.0 24.4 1.3e-07 31.4 13.6 2.5 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 EMG47357.1 - 0.0069 16.2 0.6 0.0069 16.2 0.6 2.9 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHF12_MRG_bd PF16737.5 EMG47357.1 - 0.035 13.8 0.5 0.097 12.4 0.5 1.7 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain PHD_2 PF13831.6 EMG47357.1 - 0.078 12.5 11.3 0.52 9.9 5.4 2.8 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.6 EMG47357.1 - 0.18 12.1 13.7 0.094 13.0 6.4 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EMG47357.1 - 0.58 10.3 11.9 0.85 9.8 5.4 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain L51_S25_CI-B8 PF05047.16 EMG47358.1 - 5.5e-07 29.4 0.6 9.3e-07 28.7 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain adh_short PF00106.25 EMG47359.1 - 3.5e-06 26.6 0.0 5.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG47359.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ArgJ PF01960.18 EMG47360.1 - 8.1e-148 492.1 2.1 9.2e-148 492.0 2.1 1.0 1 0 0 1 1 1 1 ArgJ family RNA_pol PF00940.19 EMG47361.1 - 1.7e-126 422.5 1.0 1.7e-126 422.5 1.0 2.0 2 0 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EMG47361.1 - 3e-16 59.7 0.0 6.5e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal tRNA_synt_1c_R1 PF04558.15 EMG47361.1 - 4.5 7.3 6.7 1.7 8.6 0.3 2.9 3 0 0 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Iwr1 PF08574.10 EMG47362.1 - 1.9e-16 60.8 12.8 1.9e-16 60.8 12.8 3.3 3 2 0 3 3 3 1 Transcription factor Iwr1 TRAPP PF04051.16 EMG47363.1 - 3.2e-19 69.1 0.0 5.3e-19 68.4 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component HydF_dimer PF18128.1 EMG47364.1 - 0.11 12.6 0.1 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Hydrogen maturase F dimerization domain Ribosomal_S16 PF00886.19 EMG47365.1 - 2.9e-19 68.9 0.0 4.3e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 NUC173 PF08161.12 EMG47366.1 - 5.4e-72 241.7 4.9 1.2e-66 224.2 0.0 4.5 5 0 0 5 5 5 2 NUC173 domain Ipi1_N PF12333.8 EMG47366.1 - 0.11 13.1 1.0 13 6.5 0.0 4.0 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation CpxA_peri PF16527.5 EMG47366.1 - 0.12 12.7 0.5 1 9.7 0.1 2.7 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain BTB PF00651.31 EMG47367.1 - 1.3e-20 73.7 0.3 3.1e-12 46.7 0.1 2.9 2 1 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 EMG47367.1 - 1.4e-06 28.4 0.0 0.00059 20.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMG47367.1 - 1.7e-06 28.4 0.0 1.6e-05 25.4 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMG47367.1 - 2.3e-06 28.1 0.0 2.9e-05 24.6 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMG47367.1 - 0.00062 20.0 0.1 5.5 7.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EMG47367.1 - 0.042 14.3 0.1 0.85 10.2 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Cnd1_N PF12922.7 EMG47367.1 - 0.046 13.6 0.2 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term ACBP PF00887.19 EMG47368.1 - 1.5e-26 92.4 0.3 4.3e-26 91.0 0.3 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein Epimerase PF01370.21 EMG47368.1 - 2.9e-12 46.6 0.5 9.5e-12 44.9 0.5 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG47368.1 - 2.3e-09 36.7 0.0 4.6e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMG47368.1 - 4e-06 26.2 0.5 0.00033 19.9 0.5 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EMG47368.1 - 1.7e-05 24.4 0.3 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EMG47368.1 - 6.7e-05 22.9 0.1 0.00019 21.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EMG47368.1 - 0.0001 21.9 0.0 0.00051 19.7 0.0 2.1 2 1 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EMG47368.1 - 0.0017 17.9 0.1 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMG47368.1 - 0.062 12.4 0.1 0.09 11.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 EMG47368.1 - 0.1 12.5 0.1 0.27 11.1 0.1 1.7 1 1 0 1 1 1 0 KR domain KcnmB2_inactiv PF09303.10 EMG47369.1 - 0.15 11.8 1.5 0.4 10.5 1.5 1.7 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Peptidase_M24 PF00557.24 EMG47370.1 - 2.5e-16 60.0 0.0 3.4e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Phosphorylase PF00343.20 EMG47371.1 - 0 1021.0 0.0 0 1020.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase PAS_10 PF13596.6 EMG47371.1 - 0.099 13.2 0.5 32 5.2 0.0 3.2 3 0 0 3 3 3 0 PAS domain Peptidase_S10 PF00450.22 EMG47372.1 - 2.4e-95 320.4 1.5 4.6e-95 319.5 0.4 1.8 2 0 0 2 2 2 1 Serine carboxypeptidase Ribosomal_S13 PF00416.22 EMG47373.1 - 3.5e-54 182.6 1.4 7.5e-54 181.5 1.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Ribosomal_L4 PF00573.22 EMG47373.1 - 4.7e-35 121.0 0.0 1.2e-34 119.7 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family DUF2746 PF10874.8 EMG47373.1 - 0.075 13.5 0.1 1.7 9.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2746) Homeodomain PF00046.29 EMG47374.1 - 3.1e-15 55.8 4.8 5.8e-15 54.9 4.8 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EMG47374.1 - 0.067 13.1 0.5 0.21 11.5 0.5 1.9 1 0 0 1 1 1 0 Homeobox KN domain Metallophos PF00149.28 EMG47375.1 - 0.00075 20.0 1.6 0.0017 18.9 1.6 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AP3D1 PF06375.11 EMG47375.1 - 0.38 11.0 15.3 0.78 10.0 7.8 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 ETRAMP PF09716.10 EMG47375.1 - 8.8 6.5 8.2 4.9 7.3 1.2 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ribosomal_L10 PF00466.20 EMG47376.1 - 1.4e-25 89.3 0.2 2.8e-25 88.3 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EMG47376.1 - 8.8e-23 80.1 0.0 1.6e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EMG47376.1 - 2.6e-08 34.3 3.1 4.1e-08 33.7 1.0 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Sigma70_r4_2 PF08281.12 EMG47377.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_10 PF04967.12 EMG47377.1 - 0.11 12.4 0.0 0.49 10.2 0.0 2.0 1 1 1 2 2 2 0 HTH DNA binding domain PWWP PF00855.17 EMG47379.1 - 9.1e-22 77.3 0.0 9.1e-22 77.3 0.0 2.2 3 0 0 3 3 3 1 PWWP domain TMEM171 PF15471.6 EMG47379.1 - 0.18 10.8 1.0 0.32 10.0 1.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 SRF-TF PF00319.18 EMG47380.1 - 4.2e-21 74.2 0.1 6.1e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Synaphin PF05835.12 EMG47380.1 - 0.19 12.0 0.4 0.19 12.0 0.4 2.5 2 1 0 2 2 2 0 Synaphin protein DUF4407 PF14362.6 EMG47380.1 - 2.4 7.4 5.4 2 7.7 4.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MRI PF15325.6 EMG47380.1 - 3.2 8.9 10.0 2.4 9.3 5.0 2.5 2 1 0 2 2 2 0 Modulator of retrovirus infection Pex14_N PF04695.13 EMG47380.1 - 3.6 8.2 14.0 6.7 7.3 14.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PSP1 PF04468.12 EMG47381.1 - 5.6e-35 119.5 0.1 5.6e-35 119.5 0.1 2.0 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Copper-fist PF00649.18 EMG47382.1 - 6.9e-20 70.2 1.6 6.9e-20 70.2 1.6 2.0 2 0 0 2 2 2 1 Copper fist DNA binding domain DUF4183 PF13799.6 EMG47383.1 - 0.042 13.7 0.3 0.38 10.6 0.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4183) TPR_2 PF07719.17 EMG47385.1 - 2.5e-29 99.0 34.7 0.02 15.0 0.1 15.1 15 2 1 16 16 16 8 Tetratricopeptide repeat TPR_1 PF00515.28 EMG47385.1 - 1.1e-28 97.8 36.8 0.0014 18.3 0.4 14.5 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_8 PF13181.6 EMG47385.1 - 5.2e-25 85.5 42.7 0.00014 21.8 0.3 13.9 16 1 0 16 16 14 8 Tetratricopeptide repeat TPR_12 PF13424.6 EMG47385.1 - 2.3e-21 75.9 13.0 8.9e-06 25.9 0.0 10.5 8 3 2 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMG47385.1 - 7.7e-19 68.1 0.9 0.0097 16.5 0.0 7.8 7 2 2 9 9 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMG47385.1 - 1.3e-17 64.0 10.4 2e-06 28.2 0.0 10.2 8 3 3 12 12 12 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMG47385.1 - 6.1e-15 54.6 7.8 0.23 12.4 0.0 11.5 10 2 2 12 12 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMG47385.1 - 1.3e-13 50.3 23.1 0.12 12.1 0.3 11.1 10 1 1 11 11 10 5 TPR repeat ANAPC3 PF12895.7 EMG47385.1 - 9.5e-10 38.6 19.3 6.1e-05 23.2 0.1 8.3 5 2 3 9 9 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EMG47385.1 - 7.4e-09 35.7 19.3 19 6.2 0.3 12.4 13 0 0 13 13 12 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMG47385.1 - 8e-08 31.9 20.1 0.15 12.0 0.0 10.1 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMG47385.1 - 3.2e-07 30.3 26.0 0.18 12.2 0.0 11.6 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMG47385.1 - 1.5e-06 27.8 14.7 0.079 13.0 0.0 10.2 14 0 0 14 14 12 1 Tetratricopeptide repeat TPR_21 PF09976.9 EMG47385.1 - 0.00021 21.0 8.8 0.22 11.2 0.2 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat-like domain PknG_TPR PF16918.5 EMG47385.1 - 0.0036 16.1 3.4 6.8 5.3 1.2 4.6 4 1 0 5 5 5 1 Protein kinase G tetratricopeptide repeat DUF2225 PF09986.9 EMG47385.1 - 0.052 13.3 15.7 0.069 12.9 1.3 4.6 3 3 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) SHNi-TPR PF10516.9 EMG47385.1 - 0.25 10.8 10.1 2.3 7.7 0.1 5.4 6 0 0 6 6 6 0 SHNi-TPR LuxT_C PF18285.1 EMG47385.1 - 0.38 11.3 2.3 11 6.7 0.0 3.4 3 0 0 3 3 3 0 Tetracycline repressor LuxT C-terminal domain Fis1_TPR_C PF14853.6 EMG47385.1 - 0.44 10.7 6.9 22 5.2 0.0 5.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 EMG47385.1 - 0.53 9.6 6.4 0.85 8.9 0.1 4.0 3 1 2 5 5 5 0 MalT-like TPR region DUF4810 PF16068.5 EMG47385.1 - 2.1 9.0 6.9 0.58 10.7 0.1 3.6 3 1 0 3 3 2 0 Domain of unknown function (DUF4810) DUF2203 PF09969.9 EMG47385.1 - 6.1 7.6 7.6 1.1e+02 3.5 0.0 3.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Streptin-Immun PF11083.8 EMG47385.1 - 9.3 6.7 15.1 0.27 11.7 1.2 4.8 4 1 0 4 4 4 0 Lantibiotic streptin immunity protein DUF3712 PF12505.8 EMG47386.1 - 0.00041 20.6 9.7 0.085 13.1 0.2 3.3 3 1 0 3 3 3 2 Protein of unknown function (DUF3712) NmrA PF05368.13 EMG47387.1 - 1.1e-07 31.6 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 EMG47387.1 - 0.00067 19.8 0.0 0.0018 18.4 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EMG47388.1 - 2.6e-09 37.0 0.3 3.9e-09 36.4 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 EMG47388.1 - 0.032 14.4 0.0 0.098 12.8 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CFEM PF05730.11 EMG47389.1 - 6.4e-10 39.0 13.2 1.7e-09 37.7 13.2 1.7 1 0 0 1 1 1 1 CFEM domain eIF-3c_N PF05470.12 EMG47389.1 - 0.31 9.3 2.0 0.35 9.1 2.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 EMG47389.1 - 0.97 7.7 11.6 1.1 7.4 11.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 EMG47389.1 - 1.7 7.2 14.1 2.1 7.0 14.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 EMG47389.1 - 2.1 6.3 16.9 2.5 6.1 16.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 EMG47389.1 - 2.2 8.0 11.0 2.7 7.8 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RIFIN PF02009.16 EMG47389.1 - 2.8 7.7 10.2 3.7 7.4 10.2 1.2 1 0 0 1 1 1 0 Rifin SWI-SNF_Ssr4 PF08549.10 EMG47389.1 - 3 6.4 12.3 3.4 6.2 12.3 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Nop14 PF04147.12 EMG47389.1 - 3.1 5.9 15.2 3.6 5.7 15.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EMG47389.1 - 4.2 6.7 16.4 4.6 6.6 16.4 1.1 1 0 0 1 1 1 0 SDA1 Spore_coat_CotO PF14153.6 EMG47389.1 - 4.2 7.3 8.7 5 7.0 8.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Raftlin PF15250.6 EMG47389.1 - 5.4 5.6 13.6 5.9 5.5 13.6 1.1 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 EMG47389.1 - 6.9 5.3 15.9 9 4.9 15.9 1.2 1 0 0 1 1 1 0 Presenilin Amidohydro_1 PF01979.20 EMG47390.1 - 1.3e-66 225.3 0.0 1.6e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMG47390.1 - 3.6e-06 26.7 0.1 0.0011 18.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EMG47390.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.16 EMG47391.1 - 2.7e-22 79.2 22.2 5.5e-18 65.0 13.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG47391.1 - 1.8e-20 73.2 13.8 2.6e-20 72.7 13.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EMG47391.1 - 4.5e-05 22.9 2.1 0.00018 20.9 0.9 2.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Methyltransf_PK PF05891.12 EMG47392.1 - 8.3e-80 267.4 0.0 9.5e-80 267.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 EMG47392.1 - 0.042 13.1 0.4 0.65 9.3 0.3 2.5 2 1 0 2 2 2 0 O-methyltransferase domain Methyltransf_25 PF13649.6 EMG47392.1 - 0.1 13.3 0.0 0.25 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Mid2 PF04478.12 EMG47393.1 - 4.1e-10 39.7 2.1 4.1e-10 39.7 2.1 2.2 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 EMG47393.1 - 0.0012 18.2 2.2 0.006 16.0 2.2 2.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Apt1 PF10351.9 EMG47393.1 - 0.27 10.0 11.8 0.34 9.7 11.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 EMG47393.1 - 0.36 10.7 15.9 0.45 10.4 15.9 1.2 1 0 0 1 1 1 0 SPX domain DUF1180 PF06679.12 EMG47393.1 - 3.9 7.9 15.7 69 3.8 15.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Peptidase_S64 PF08192.11 EMG47393.1 - 5.7 5.3 20.3 7 5.0 20.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Siva PF05458.12 EMG47394.1 - 2.5 7.8 8.6 0.92 9.2 4.8 2.1 2 1 1 3 3 3 0 Cd27 binding protein (Siva) DUF4541 PF15074.6 EMG47394.1 - 3 8.5 9.1 0.54 10.9 1.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4541) RRM_1 PF00076.22 EMG47395.1 - 1.8e-54 181.5 1.6 1.8e-19 69.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMG47395.1 - 0.00012 21.9 0.0 6.2 6.8 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EMG47395.1 - 0.0026 17.8 0.1 0.57 10.3 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif RRM_Rrp7 PF17799.1 EMG47395.1 - 0.0059 16.4 0.0 8.7 6.1 0.0 3.1 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain DbpA PF03880.15 EMG47395.1 - 0.02 14.9 0.0 34 4.5 0.0 3.3 3 0 0 3 3 3 0 DbpA RNA binding domain DUF1388 PF07142.12 EMG47395.1 - 0.034 14.1 0.9 0.058 13.4 0.9 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) DNA_topoisoIV PF00521.20 EMG47395.1 - 0.2 10.5 0.0 4.8 6.0 0.0 2.2 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A DUF1325 PF07039.11 EMG47396.1 - 9.4e-34 116.3 0.2 2.1e-33 115.2 0.0 1.7 2 0 0 2 2 2 1 SGF29 tudor-like domain Tudor_3 PF18115.1 EMG47396.1 - 6.2e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain RED_C PF07807.11 EMG47396.1 - 0.044 14.2 2.2 3.3 8.2 1.7 2.2 2 0 0 2 2 2 0 RED-like protein C-terminal region DUF4537 PF15057.6 EMG47396.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF4407 PF14362.6 EMG47396.1 - 0.48 9.7 2.7 0.63 9.3 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 EMG47396.1 - 7.5 5.3 5.7 9 5.1 5.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PLDc_2 PF13091.6 EMG47397.1 - 7.7e-16 58.2 0.0 5.6e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EMG47397.1 - 3.1e-08 33.5 0.0 0.00034 20.7 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif ASPRs PF17641.2 EMG47397.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related IBN_N PF03810.19 EMG47398.1 - 4.1e-05 23.4 4.6 6.3e-05 22.8 0.2 3.4 3 1 1 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EMG47398.1 - 0.0018 18.4 3.6 0.015 15.4 0.0 4.1 3 1 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 EMG47398.1 - 0.054 13.8 0.2 13 6.4 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat FAM86 PF14904.6 EMG47398.1 - 0.056 13.5 0.1 0.24 11.5 0.1 2.1 1 0 0 1 1 1 0 Family of unknown function Condensin2nSMC PF12422.8 EMG47398.1 - 0.11 12.6 1.5 2.5 8.3 0.1 2.9 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit FANCI_S2 PF14676.6 EMG47398.1 - 2 8.7 9.7 0.29 11.4 0.2 3.2 3 0 0 3 3 3 0 FANCI solenoid 2 DUF2015 PF09435.10 EMG47399.1 - 1.6e-34 118.1 0.3 1.9e-34 117.9 0.3 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) TMEM151 PF14857.6 EMG47399.1 - 0.22 10.4 0.1 0.25 10.2 0.1 1.1 1 0 0 1 1 1 0 TMEM151 family Epimerase PF01370.21 EMG47400.1 - 2e-14 53.6 0.0 3.8e-14 52.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMG47400.1 - 5.2e-07 29.1 0.0 0.002 17.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EMG47400.1 - 1.1e-06 27.9 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMG47400.1 - 3.6e-06 27.0 0.0 1.6e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMG47400.1 - 5.4e-05 22.9 0.1 0.001 18.7 0.0 2.4 2 1 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EMG47400.1 - 5.8e-05 22.6 0.3 0.00023 20.7 0.0 2.0 2 1 0 3 3 3 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EMG47400.1 - 7.1e-05 22.3 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EMG47400.1 - 0.018 14.2 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EMG47400.1 - 0.055 12.6 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 RmlD substrate binding domain CRISPR_Cas9_WED PF18061.1 EMG47400.1 - 0.083 13.0 0.4 0.29 11.2 0.1 1.9 2 1 0 2 2 2 0 CRISPR-Cas9 WED domain Dcc1 PF09724.9 EMG47401.1 - 9e-62 209.3 0.4 1.1e-61 209.1 0.4 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Ino80_Iec3 PF14612.6 EMG47402.1 - 2 9.0 10.2 4.2 8.0 10.2 1.4 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling RR_TM4-6 PF06459.12 EMG47402.1 - 6 6.6 13.0 0.89 9.3 7.2 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4661 PF15576.6 EMG47402.1 - 7 6.5 13.5 0.047 13.6 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) Sugar_tr PF00083.24 EMG47403.1 - 1.2e-125 419.9 19.7 1.4e-125 419.7 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG47403.1 - 6e-27 94.5 17.8 6e-27 94.5 17.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 EMG47403.1 - 0.019 15.2 0.8 0.019 15.2 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) Mito_carr PF00153.27 EMG47404.1 - 2.2e-52 174.9 0.9 6.1e-18 64.5 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Aminotran_5 PF00266.19 EMG47405.1 - 3.2e-96 322.5 0.0 3.8e-96 322.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMG47405.1 - 3.1e-07 30.0 0.1 4.6e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 EMG47405.1 - 0.00019 20.3 0.1 0.00029 19.7 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 EMG47405.1 - 0.0012 18.3 0.1 0.0043 16.4 0.1 1.9 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Iso_dh PF00180.20 EMG47406.1 - 3.7e-123 411.1 0.0 4.4e-123 410.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3507 PF12015.8 EMG47407.1 - 4.4e-71 238.3 0.6 8.5e-71 237.4 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) NAD_binding_4 PF07993.12 EMG47408.1 - 6.6e-08 32.0 0.0 3.2e-07 29.8 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein Epimerase PF01370.21 EMG47408.1 - 4.7e-06 26.3 0.0 6.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EMG47408.1 - 0.0087 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EMG47408.1 - 0.01 14.9 0.0 0.013 14.5 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMG47408.1 - 0.034 13.3 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain HPP PF04982.13 EMG47409.1 - 1.2e-37 128.8 3.7 1.9e-37 128.1 3.7 1.3 1 0 0 1 1 1 1 HPP family E1-E2_ATPase PF00122.20 EMG47410.1 - 4.8e-50 169.6 1.3 4.8e-50 169.6 1.3 2.7 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMG47410.1 - 2.5e-43 147.9 2.0 2.5e-43 147.9 2.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMG47410.1 - 5.4e-24 85.6 0.2 1e-18 68.4 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMG47410.1 - 1.4e-14 53.5 0.1 4e-14 52.0 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EMG47410.1 - 6.2e-14 51.8 0.0 2.5e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EMG47410.1 - 1.4e-09 38.1 1.0 3.8e-06 26.8 0.8 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 EMG47410.1 - 0.011 15.7 0.0 0.036 14.0 0.0 1.9 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Sua5_yciO_yrdC PF01300.18 EMG47411.1 - 6.1e-50 169.2 0.0 8.7e-50 168.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EMG47411.1 - 2.5e-30 105.8 0.0 4.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding UDPG_MGDP_dh PF00984.19 EMG47411.1 - 0.0097 16.1 0.0 0.077 13.2 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Telomere_reg-2 PF10193.9 EMG47413.1 - 6.1e-28 97.4 0.1 1.6e-27 96.1 0.1 1.8 1 0 0 1 1 1 1 Telomere length regulation protein Thi4 PF01946.17 EMG47414.1 - 0.084 12.1 0.0 0.89 8.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Aa_trans PF01490.18 EMG47415.1 - 2.1e-64 217.8 28.0 2.8e-64 217.3 28.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MerC PF03203.14 EMG47415.1 - 0.006 17.0 5.7 0.006 17.0 5.7 3.8 3 1 1 4 4 4 1 MerC mercury resistance protein FUSC PF04632.12 EMG47415.1 - 1.7 7.0 4.9 2.7 6.4 4.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family FMN_bind_2 PF04299.12 EMG47416.1 - 5.8e-57 192.1 0.4 7.1e-57 191.8 0.4 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain RRM_1 PF00076.22 EMG47417.1 - 3.2e-17 62.1 0.0 5.5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.11 EMG47417.1 - 0.025 15.3 11.5 0.047 14.4 11.5 1.4 1 0 0 1 1 1 0 Glycine rich protein family FoP_duplication PF13865.6 EMG47417.1 - 10 6.8 21.1 24 5.6 21.1 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Fasciclin PF02469.22 EMG47418.1 - 1.4e-16 60.8 5.3 1.3e-05 25.4 0.0 5.3 5 1 1 6 6 6 3 Fasciclin domain PND PF17949.1 EMG47418.1 - 0.025 14.8 0.1 4.5 7.5 0.0 2.8 2 0 0 2 2 2 0 FANCM pseudonuclease domain BRCA-2_helical PF09169.10 EMG47418.1 - 0.16 11.6 0.3 0.37 10.4 0.3 1.5 1 0 0 1 1 1 0 BRCA2, helical Ferric_reduct PF01794.19 EMG47419.1 - 7e-20 71.4 6.4 7e-20 71.4 6.4 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMG47419.1 - 8.8e-19 68.2 0.4 1.4e-18 67.5 0.4 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMG47419.1 - 8.4e-14 51.6 0.0 2.3e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ureide_permease PF07168.11 EMG47419.1 - 0.014 14.2 1.0 0.025 13.3 1.0 1.3 1 0 0 1 1 1 0 Ureide permease DUF4405 PF14358.6 EMG47419.1 - 0.32 11.6 5.9 0.42 11.2 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) RhoGAP PF00620.27 EMG47420.1 - 8.1e-39 132.9 1.9 3.9e-23 82.0 0.0 2.7 3 0 0 3 3 3 2 RhoGAP domain Peptidase_M28 PF04389.17 EMG47421.1 - 1.6e-21 76.9 0.0 3.3e-21 75.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 EMG47421.1 - 1.6e-19 70.2 0.0 3.1e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 EMG47421.1 - 2.7e-14 52.9 0.1 6.9e-14 51.6 0.1 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 EMG47421.1 - 7.7e-05 22.3 0.0 0.00021 20.8 0.0 1.7 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.28 EMG47421.1 - 0.067 12.9 0.1 0.25 11.0 0.1 2.0 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 YcgR PF07317.12 EMG47422.1 - 0.077 12.9 0.4 0.22 11.4 0.4 1.8 1 0 0 1 1 1 0 Flagellar regulator YcgR MID_MedPIWI PF18296.1 EMG47423.1 - 3.7 7.3 12.1 0.62 9.8 6.7 2.0 2 0 0 2 2 2 0 MID domain of medPIWI Alb1 PF09135.11 EMG47424.1 - 6e-06 27.1 7.6 6e-06 27.1 7.6 1.5 1 1 0 1 1 1 1 Alb1 Inhibitor_I69 PF13734.6 EMG47424.1 - 0.005 17.2 3.1 0.0053 17.2 0.2 1.9 2 0 0 2 2 2 1 Spi protease inhibitor Ribul_P_3_epim PF00834.19 EMG47425.1 - 5.9e-69 231.4 0.0 7e-69 231.2 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Radical_SAM PF04055.21 EMG47425.1 - 0.057 13.8 0.0 0.44 10.9 0.0 2.0 1 1 1 2 2 2 0 Radical SAM superfamily Fis1_TPR_C PF14853.6 EMG47426.1 - 3.3e-24 84.7 0.1 6.8e-24 83.7 0.1 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat A_deamin PF02137.18 EMG47426.1 - 1.4e-20 74.0 0.0 5.2e-20 72.1 0.0 2.0 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Fis1_TPR_N PF14852.6 EMG47426.1 - 1.1e-15 56.9 0.1 2.7e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EMG47426.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMG47426.1 - 0.14 12.4 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Sod_Fe_C PF02777.18 EMG47427.1 - 6.4e-31 106.6 1.3 1.1e-30 105.7 1.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EMG47427.1 - 5.5e-27 94.1 1.0 1e-26 93.2 1.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain FAD_binding_8 PF08022.12 EMG47428.1 - 1.7e-13 50.6 0.0 4.5e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EMG47428.1 - 4.5e-12 46.2 10.8 8.1e-12 45.4 10.8 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMG47428.1 - 3.4e-10 40.3 0.0 5.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain BAR PF03114.18 EMG47429.1 - 6e-53 179.9 3.7 8.8e-53 179.4 3.7 1.3 1 0 0 1 1 1 1 BAR domain DUF4164 PF13747.6 EMG47429.1 - 0.029 14.6 1.5 0.13 12.6 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) ANAPC4_WD40 PF12894.7 EMG47429.1 - 0.089 13.1 0.0 5.3 7.4 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Jnk-SapK_ap_N PF09744.9 EMG47429.1 - 1.4 9.1 7.2 0.16 12.2 2.2 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DEAD_2 PF06733.15 EMG47431.1 - 3.1e-54 183.2 0.7 7e-54 182.1 0.7 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EMG47431.1 - 2e-48 164.6 2.0 5.3e-44 150.2 0.6 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EMG47431.1 - 6.4e-44 150.1 0.0 1.9e-43 148.6 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EMG47431.1 - 0.0011 19.0 0.0 0.35 10.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EMG47431.1 - 0.0022 17.8 0.0 0.57 9.9 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase YtxC PF08812.11 EMG47431.1 - 0.15 11.6 0.1 0.15 11.6 0.1 2.8 3 0 0 3 3 3 0 YtxC-like family ADK PF00406.22 EMG47432.1 - 5e-45 153.3 0.0 6e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EMG47432.1 - 1.3e-20 74.2 0.0 2.1e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EMG47432.1 - 9.7e-13 47.9 0.0 1.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EMG47432.1 - 1.5e-05 25.6 0.0 2.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMG47432.1 - 0.011 15.9 0.0 0.032 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMG47432.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 EMG47432.1 - 0.12 11.8 0.3 0.37 10.2 0.1 1.7 1 1 0 2 2 2 0 Chromatin associated protein KTI12 SRP54 PF00448.22 EMG47432.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 EMG47432.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Leo1 PF04004.13 EMG47433.1 - 3.6e-38 131.0 0.8 3.6e-38 131.0 0.8 2.9 2 1 0 2 2 2 1 Leo1-like protein PH_10 PF15411.6 EMG47434.1 - 0.001 19.3 1.1 0.9 9.8 0.0 3.1 2 1 1 3 3 3 2 Pleckstrin homology domain zf-RING_5 PF14634.6 EMG47434.1 - 0.91 9.5 8.7 10 6.2 0.0 2.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 EMG47434.1 - 2 8.8 10.8 4.4 7.7 8.0 2.6 2 0 0 2 2 2 0 Ring finger domain YchF-GTPase_C PF06071.13 EMG47435.1 - 2.2e-05 24.6 0.1 2.2e-05 24.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF933) zinc_ribbon_4 PF13717.6 EMG47435.1 - 0.041 13.8 0.3 2 8.4 0.0 2.0 1 1 1 2 2 2 0 zinc-ribbon domain p450 PF00067.22 EMG47436.1 - 1e-57 196.0 0.1 1.3e-57 195.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thioredoxin PF00085.20 EMG47437.1 - 2.7e-06 27.3 0.1 7.5e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EMG47437.1 - 0.00014 20.9 1.8 0.00017 20.7 1.8 1.1 1 0 0 1 1 1 1 Phosducin TraF PF13728.6 EMG47437.1 - 0.062 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein EF-hand_7 PF13499.6 EMG47437.1 - 0.31 11.5 5.9 0.8 10.2 5.9 1.6 1 0 0 1 1 1 0 EF-hand domain pair Roughex PF06020.11 EMG47438.1 - 0.0065 15.6 10.7 0.0093 15.1 10.7 1.3 1 0 0 1 1 1 1 Drosophila roughex protein Cadherin_C PF01049.17 EMG47438.1 - 0.064 13.6 8.9 0.055 13.8 7.2 1.8 1 1 1 2 2 2 0 Cadherin cytoplasmic region DTHCT PF08070.11 EMG47438.1 - 0.44 11.3 3.2 0.66 10.7 0.7 2.1 2 0 0 2 2 2 0 DTHCT (NUC029) region PAXNEB PF05625.11 EMG47438.1 - 1.8 7.6 17.4 2.4 7.2 17.4 1.3 1 1 0 1 1 1 0 PAXNEB protein Presenilin PF01080.17 EMG47438.1 - 1.8 7.2 5.0 1.9 7.2 5.0 1.3 1 0 0 1 1 1 0 Presenilin PRELI PF04707.14 EMG47439.1 - 4.5e-44 150.0 0.5 5.8e-44 149.7 0.5 1.2 1 0 0 1 1 1 1 PRELI-like family DDE_Tnp_ISL3 PF01610.17 EMG47439.1 - 0.012 15.3 0.2 0.018 14.8 0.2 1.2 1 0 0 1 1 1 0 Transposase MutS_V PF00488.21 EMG47441.1 - 1.4e-79 266.6 0.1 2.5e-79 265.7 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMG47441.1 - 7.3e-31 107.9 3.8 8.2e-31 107.7 1.3 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EMG47441.1 - 1.3e-16 60.7 0.7 1.3e-16 60.7 0.7 2.7 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EMG47441.1 - 4.4e-11 43.2 5.1 2.7e-10 40.7 1.0 2.7 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 EMG47441.1 - 5.8e-06 26.5 0.8 8.2e-05 22.8 0.2 2.4 2 0 0 2 2 2 1 MutS domain I DUF3781 PF12636.7 EMG47441.1 - 0.09 12.7 2.1 0.36 10.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) AAA_27 PF13514.6 EMG47441.1 - 0.12 12.0 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EMG47441.1 - 1.4 9.4 0.0 1.4 9.4 0.0 3.7 3 1 0 3 3 3 0 AAA domain Ceramidase PF05875.12 EMG47442.1 - 5.5e-61 206.3 5.0 6.3e-61 206.1 5.0 1.1 1 0 0 1 1 1 1 Ceramidase MerC PF03203.14 EMG47442.1 - 0.83 10.1 6.7 10 6.6 1.3 2.3 1 1 1 2 2 2 0 MerC mercury resistance protein RNA_pol_Rpb1_1 PF04997.12 EMG47443.1 - 6.3e-85 285.2 0.2 9.9e-85 284.6 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EMG47443.1 - 3.6e-82 275.8 0.1 6.4e-82 275.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EMG47443.1 - 5.5e-74 247.9 0.0 2.3e-73 245.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EMG47443.1 - 3.5e-39 134.3 0.0 9.9e-39 132.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EMG47443.1 - 1.8e-31 108.3 0.2 1.1e-30 105.8 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 VHS PF00790.19 EMG47443.1 - 0.05 13.4 0.8 0.13 12.1 0.8 1.6 1 0 0 1 1 1 0 VHS domain DUF2786 PF10979.8 EMG47443.1 - 0.059 13.3 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) COPI_assoc PF08507.10 EMG47444.1 - 1.7e-35 121.9 5.0 1.9e-35 121.8 5.0 1.0 1 0 0 1 1 1 1 COPI associated protein DUF3784 PF12650.7 EMG47444.1 - 0.38 11.0 0.1 0.38 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) HSA PF07529.13 EMG47445.1 - 1.1e-11 44.8 0.5 1.1e-11 44.8 0.5 4.4 5 0 0 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.6 EMG47445.1 - 7.9e-09 35.6 0.5 7.9e-09 35.6 0.5 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMG47445.1 - 0.0096 16.1 0.1 0.025 14.8 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Nipped-B_C PF12830.7 EMG47446.1 - 3.5e-31 108.6 10.3 1.8e-29 103.0 0.5 4.8 4 1 0 4 4 4 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EMG47446.1 - 3.9e-12 46.2 0.8 2.5e-11 43.7 0.4 2.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 EMG47446.1 - 0.00074 19.9 0.1 0.2 12.1 0.0 4.0 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 EMG47446.1 - 0.055 13.7 0.5 17 6.0 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat LUC7 PF03194.15 EMG47446.1 - 0.079 12.6 2.9 0.16 11.6 2.9 1.4 1 0 0 1 1 1 0 LUC7 N_terminus SATase_N PF06426.14 EMG47446.1 - 0.091 13.1 0.5 18 5.8 0.0 3.6 4 0 0 4 4 4 0 Serine acetyltransferase, N-terminal SAS4 PF15460.6 EMG47447.1 - 9.7e-24 83.4 9.3 9.7e-24 83.4 9.3 1.7 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 PBP1_TM PF14812.6 EMG47447.1 - 1.5 9.3 9.2 0.15 12.5 4.7 1.7 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Metallophos PF00149.28 EMG47448.1 - 3.6e-12 47.2 3.3 5.8e-12 46.5 3.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sec10 PF07393.11 EMG47449.1 - 1e-179 599.4 18.4 1.2e-179 599.1 18.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF16 PF01519.16 EMG47449.1 - 0.014 15.8 2.4 0.34 11.4 0.8 3.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 CBM_X2 PF03442.14 EMG47449.1 - 0.12 12.5 1.9 0.17 12.0 0.3 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain X2 ubiquitin PF00240.23 EMG47450.1 - 3.9e-34 116.2 0.6 7.5e-34 115.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EMG47450.1 - 6.3e-27 93.5 1.3 1.6e-26 92.2 1.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EMG47450.1 - 2.6e-16 59.2 0.7 4.7e-16 58.4 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMG47450.1 - 2.4e-05 24.7 0.4 0.00012 22.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMG47450.1 - 0.0013 18.8 0.5 0.0028 17.8 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EMG47450.1 - 0.0035 17.7 0.3 0.0076 16.6 0.0 1.6 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EMG47450.1 - 0.0053 16.7 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EMG47450.1 - 0.011 16.3 0.5 0.016 15.8 0.5 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EMG47450.1 - 0.019 15.0 1.0 5.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 EMG47450.1 - 0.028 14.6 0.2 0.046 14.0 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Spc110_C PF18520.1 EMG47451.1 - 0.051 13.2 0.5 0.19 11.3 0.5 2.0 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain LAM_C PF12544.8 EMG47451.1 - 0.14 12.4 6.1 0.53 10.5 2.0 3.6 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Spc7 PF08317.11 EMG47451.1 - 0.33 9.8 108.9 0.019 13.9 13.1 6.4 1 1 5 6 6 6 0 Spc7 kinetochore protein MbeD_MobD PF04899.12 EMG47451.1 - 0.75 9.9 24.6 0.94 9.6 0.1 7.3 5 3 3 8 8 8 0 MbeD/MobD like FUSC PF04632.12 EMG47451.1 - 7.8 4.9 7.8 1.7 7.1 0.9 2.5 2 1 0 2 2 2 0 Fusaric acid resistance protein family HOOK PF05622.12 EMG47451.1 - 9.2 4.3 106.1 0.72 7.9 16.1 5.2 1 1 2 4 4 4 0 HOOK protein Glycos_transf_3 PF00591.21 EMG47452.1 - 1e-79 267.8 0.0 1.2e-79 267.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EMG47452.1 - 5.3e-12 45.4 0.0 1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Sec63 PF02889.16 EMG47453.1 - 4.3e-143 475.0 12.7 4.1e-80 268.6 0.8 2.9 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 EMG47453.1 - 1.9e-42 145.0 1.0 1.1e-26 93.7 0.2 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EMG47453.1 - 1.3e-25 90.4 0.2 2e-14 54.0 0.1 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMG47453.1 - 7e-11 42.5 0.2 8.7e-09 35.7 0.0 3.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_PWI PF18149.1 EMG47453.1 - 7.9e-09 35.7 1.7 2.8e-08 33.9 0.6 2.6 2 0 0 2 2 2 1 N-terminal helicase PWI domain AAA_22 PF13401.6 EMG47453.1 - 0.00044 20.5 0.0 0.0065 16.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EMG47453.1 - 0.0089 15.8 0.1 5.1 6.8 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein E1_dh PF00676.20 EMG47454.1 - 4.9e-119 396.7 0.5 6e-119 396.4 0.5 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EMG47454.1 - 0.0031 16.8 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.6 EMG47454.1 - 0.079 13.9 4.1 0.36 11.8 0.2 3.1 2 2 1 3 3 3 0 KRTAP type 7 family DUF3759 PF12585.8 EMG47455.1 - 1.7e-37 127.3 6.4 2e-37 127.1 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DPRP PF04244.13 EMG47455.1 - 0.0095 15.8 1.0 0.49 10.2 0.1 2.1 1 1 1 2 2 2 2 Deoxyribodipyrimidine photo-lyase-related protein Serine_protease PF18405.1 EMG47455.1 - 0.18 10.9 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Gammaproteobacterial serine protease PH PF00169.29 EMG47456.1 - 0.01 16.4 0.7 0.13 12.8 0.0 2.9 2 1 0 2 2 2 1 PH domain zf-RING_2 PF13639.6 EMG47456.1 - 0.026 14.9 3.5 0.068 13.5 3.5 1.7 1 0 0 1 1 1 0 Ring finger domain Spo7_2_N PF15407.6 EMG47457.1 - 1.2e-18 66.5 2.6 2.9e-17 62.1 0.0 3.2 3 0 0 3 3 3 1 Sporulation protein family 7 PH_4 PF15404.6 EMG47457.1 - 3.8e-12 46.4 2.3 1.6e-11 44.4 0.2 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EMG47457.1 - 8.4e-07 29.5 9.5 0.0063 17.0 0.1 4.1 4 0 0 4 4 4 3 PH domain Suc_Fer-like PF06999.12 EMG47458.1 - 2.7e-44 151.4 0.0 3.1e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Colicin_Pyocin PF01320.18 EMG47458.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein Flocculin_t3 PF13928.6 EMG47459.1 - 0.03 14.8 10.4 0.03 14.8 10.4 6.7 2 2 3 5 5 5 0 Flocculin type 3 repeat DUF5628 PF18621.1 EMG47459.1 - 0.21 12.1 15.5 6.4 7.3 1.0 3.5 1 1 2 3 3 3 0 Family of unknown function (DUF5628) tRNA_anti-like PF12869.7 EMG47459.1 - 0.33 10.6 4.8 8.6 6.0 0.2 3.0 1 1 2 3 3 3 0 tRNA_anti-like Pput2613-deam PF14427.6 EMG47459.1 - 1.4 8.8 11.4 3.4 7.6 0.7 3.6 1 1 3 4 4 4 0 Pput_2613-like deaminase Hyr1 PF15789.5 EMG47459.1 - 9.1 5.9 93.5 0.19 11.3 12.1 6.3 4 2 1 5 5 5 0 Hyphally regulated cell wall GPI-anchored protein 1 DUF5004 PF16395.5 EMG47460.1 - 0.084 12.9 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5004) Clusterin PF01093.17 EMG47462.1 - 0.038 13.0 2.3 0.059 12.4 2.3 1.2 1 0 0 1 1 1 0 Clusterin E2R135 PF11570.8 EMG47462.1 - 0.066 13.5 1.9 0.12 12.7 1.9 1.3 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 DUF2457 PF10446.9 EMG47462.1 - 1.7 7.7 9.9 2.1 7.4 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TPR_1 PF00515.28 EMG47464.1 - 3.3e-23 80.5 14.6 1.4e-05 24.7 0.7 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EMG47464.1 - 8e-18 63.1 14.5 0.0043 17.1 1.4 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EMG47464.1 - 9.8e-16 56.6 19.4 0.00012 22.0 0.0 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMG47464.1 - 2.4e-13 49.5 2.5 4.6e-08 32.6 0.0 4.5 2 2 2 4 4 4 2 TPR repeat TPR_14 PF13428.6 EMG47464.1 - 9.5e-13 47.8 1.9 3.1e-05 24.4 0.0 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMG47464.1 - 1.2e-10 41.9 0.7 9.2e-07 29.4 0.0 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMG47464.1 - 1.1e-09 38.5 9.3 0.0085 16.4 0.0 4.7 3 2 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMG47464.1 - 6.7e-08 32.4 2.3 0.015 15.6 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMG47464.1 - 1.5e-07 31.8 1.1 0.1 13.1 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.10 EMG47464.1 - 2.9e-06 26.5 0.0 0.00041 19.5 0.0 2.1 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 EMG47464.1 - 4.2e-05 23.7 14.2 0.32 11.2 0.2 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EMG47464.1 - 0.00042 20.4 0.2 0.35 11.1 0.0 2.8 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMG47464.1 - 0.0015 18.4 4.4 0.12 12.4 0.1 4.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMG47464.1 - 0.017 15.8 13.1 21 6.0 0.0 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.7 EMG47464.1 - 0.02 14.9 0.4 0.32 11.1 0.0 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) Sel1 PF08238.12 EMG47464.1 - 0.11 13.3 2.7 25 5.7 0.3 3.6 4 0 0 4 4 2 0 Sel1 repeat BTAD PF03704.17 EMG47464.1 - 0.35 11.3 3.4 0.75 10.2 0.2 2.6 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Aminotran_1_2 PF00155.21 EMG47465.1 - 5.1e-40 137.8 0.0 6.4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C3HC4_3 PF13920.6 EMG47466.1 - 1.5e-07 31.2 12.0 2.3e-07 30.5 12.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMG47466.1 - 0.4 10.6 11.5 0.76 9.7 11.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Arf PF00025.21 EMG47467.1 - 6.5e-79 263.4 0.1 7.5e-79 263.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMG47467.1 - 3.2e-15 56.4 0.1 4.3e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EMG47467.1 - 4.7e-14 52.3 0.0 5.5e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EMG47467.1 - 6.8e-14 51.7 0.0 8e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EMG47467.1 - 1.1e-12 47.9 0.9 7.9e-09 35.1 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EMG47467.1 - 2.4e-11 43.4 0.0 2.9e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMG47467.1 - 4.3e-06 26.8 0.1 6.6e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EMG47467.1 - 0.0068 15.7 0.9 0.027 13.8 0.9 1.9 1 1 0 1 1 1 1 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 EMG47467.1 - 0.029 14.6 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 cobW PF02492.19 EMG47467.1 - 0.054 13.1 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 EMG47467.1 - 0.22 11.1 0.8 0.68 9.5 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ECH_1 PF00378.20 EMG47468.1 - 4.3e-19 68.8 0.1 3.2e-18 66.0 0.1 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMG47468.1 - 1.1e-09 38.2 0.0 1.4e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NPR3 PF03666.13 EMG47469.1 - 4e-120 401.8 9.0 3.9e-106 355.7 5.5 4.2 3 2 1 4 4 4 2 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.6 EMG47469.1 - 6.3 6.5 6.3 4.2 7.0 0.6 2.6 2 0 0 2 2 2 0 FAM176 family ECH_1 PF00378.20 EMG47470.1 - 1.8e-12 47.1 0.1 2e-12 47.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMG47470.1 - 1.1e-07 31.7 0.1 1.2e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PROCN PF08083.11 EMG47471.1 - 9.3e-227 752.4 11.2 1.5e-226 751.8 11.2 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EMG47471.1 - 8e-125 415.0 0.4 1.4e-124 414.2 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EMG47471.1 - 1.5e-83 278.5 0.8 6e-83 276.6 0.8 2.1 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EMG47471.1 - 1.4e-75 252.4 2.6 4.2e-75 250.8 2.6 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EMG47471.1 - 3.6e-72 240.7 0.0 8.6e-72 239.5 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 EMG47471.1 - 1.8e-48 163.5 0.1 4.4e-48 162.3 0.1 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 EMG47471.1 - 1.5e-46 156.6 1.1 5.1e-46 154.9 1.1 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Av_adeno_fibre PF06536.11 EMG47472.1 - 0.1 12.5 0.2 3.7 7.5 0.1 2.9 3 0 0 3 3 3 0 Avian adenovirus fibre, N-terminal Histidinol_dh PF00815.20 EMG47473.1 - 3.2e-155 517.2 1.1 3.2e-155 517.2 1.1 1.9 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.18 EMG47473.1 - 6.4e-21 74.0 0.1 1.5e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase TPR_1 PF00515.28 EMG47473.1 - 6.8e-20 70.0 6.8 3.4e-06 26.7 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMG47473.1 - 1.7e-18 66.0 6.1 1.2e-05 24.8 0.0 5.8 5 1 1 6 6 6 4 TPR repeat TPR_17 PF13431.6 EMG47473.1 - 3.8e-17 61.4 6.4 0.0023 18.2 0.0 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat PRA-PH PF01503.17 EMG47473.1 - 6e-14 52.3 2.8 6.4e-14 52.2 0.1 2.5 3 0 0 3 3 2 1 Phosphoribosyl-ATP pyrophosphohydrolase TPR_2 PF07719.17 EMG47473.1 - 7.6e-14 50.6 11.5 0.0015 18.5 0.1 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMG47473.1 - 2.5e-12 46.5 3.7 0.0057 17.4 0.0 5.7 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EMG47473.1 - 9.8e-12 44.1 5.3 0.034 14.3 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMG47473.1 - 4.8e-11 43.0 5.0 0.033 14.7 0.1 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 EMG47473.1 - 2.7e-10 40.7 2.1 0.0018 18.9 0.0 4.6 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.6 EMG47473.1 - 1.2e-06 28.7 0.5 0.074 13.4 0.1 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EMG47473.1 - 3e-06 27.3 0.1 0.086 13.0 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMG47473.1 - 2.1e-05 24.7 3.6 0.027 14.8 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMG47473.1 - 0.0016 18.9 1.8 86 4.1 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMG47473.1 - 0.0074 16.2 0.4 13 6.1 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG47473.1 - 0.0088 16.3 4.4 0.053 13.8 0.1 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 RNR_inhib PF08591.10 EMG47474.1 - 1.2e-05 26.6 0.5 3.9e-05 24.9 0.5 1.9 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Aminotran_3 PF00202.21 EMG47475.1 - 1.5e-120 402.6 0.0 1.8e-120 402.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMG47475.1 - 0.0013 18.0 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EMG47475.1 - 0.0068 15.7 0.0 0.02 14.2 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EMG47476.1 - 1.2e-142 475.0 0.0 1.4e-142 474.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EMG47476.1 - 3.9e-09 36.3 0.1 8.8e-09 35.1 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EMG47476.1 - 1.4e-08 34.1 0.5 2.2e-08 33.5 0.5 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMG47476.1 - 2.3e-08 33.6 0.0 3.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 EMG47476.1 - 0.00083 18.0 0.1 0.0012 17.5 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 EMG47476.1 - 0.0044 16.3 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 EMG47476.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Asparaginase_C PF17763.1 EMG47476.1 - 0.059 13.6 0.0 0.17 12.1 0.0 1.7 1 1 1 2 2 2 0 Glutaminase/Asparaginase C-terminal domain BRK PF07533.16 EMG47476.1 - 0.15 11.7 0.0 0.45 10.2 0.0 1.8 1 0 0 1 1 1 0 BRK domain SUR7 PF06687.12 EMG47477.1 - 8.9e-16 58.2 17.5 1.2e-15 57.8 17.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF3341 PF11821.8 EMG47477.1 - 0.4 10.3 2.4 0.24 11.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) DEAD PF00270.29 EMG47478.1 - 3.8e-36 124.5 0.0 7e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG47478.1 - 1.4e-25 89.8 0.1 3.1e-24 85.5 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG47478.1 - 1.1e-08 35.3 0.0 2.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EMG47478.1 - 0.022 14.1 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit T5orf172 PF10544.9 EMG47479.1 - 4.1e-09 36.9 1.5 5.1e-08 33.4 1.5 2.6 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EMG47479.1 - 4.9e-09 36.7 0.6 2.6e-08 34.4 0.6 2.1 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 JmjC PF02373.22 EMG47480.1 - 3.2e-41 140.4 0.2 1.2e-40 138.5 0.2 2.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EMG47480.1 - 1.2e-11 44.3 7.1 1.2e-11 44.3 7.1 3.2 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 EMG47480.1 - 7.3e-11 41.8 0.0 1.9e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.6 EMG47480.1 - 0.0002 20.8 2.2 0.0023 17.5 0.6 2.6 2 0 0 2 2 2 1 PHD-finger ARID PF01388.21 EMG47480.1 - 0.0047 17.6 0.3 0.016 15.9 0.1 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DUF2318 PF10080.9 EMG47480.1 - 0.023 14.8 1.0 0.28 11.3 0.2 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Prok-RING_1 PF14446.6 EMG47480.1 - 4.9 7.2 8.5 1 9.4 3.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 P5CR_dimer PF14748.6 EMG47481.1 - 3.4e-34 117.2 1.6 7.4e-34 116.1 1.6 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EMG47481.1 - 1.3e-14 54.5 0.1 3.5e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EMG47481.1 - 0.0013 18.3 0.1 0.0033 17.1 0.1 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EMG47481.1 - 0.0036 17.3 0.7 0.026 14.5 0.7 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 EMG47481.1 - 0.029 14.6 0.0 0.061 13.6 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ATP-synt_ab PF00006.25 EMG47482.1 - 3.6e-62 209.8 0.0 5.8e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EMG47482.1 - 4.6e-23 81.5 1.4 4.6e-23 81.5 1.4 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 EMG47482.1 - 0.0036 16.7 0.2 0.0063 15.9 0.2 1.4 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.22 EMG47482.1 - 0.014 14.6 0.4 0.076 12.2 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 EMG47482.1 - 0.045 13.7 0.1 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EMG47482.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EMG47482.1 - 0.059 13.8 0.1 0.24 11.8 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EMG47482.1 - 0.1 12.9 1.4 0.48 10.8 0.2 2.3 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EMG47482.1 - 0.1 13.0 0.0 0.68 10.4 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMG47482.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase T3SS_ATPase_C PF18269.1 EMG47482.1 - 0.2 11.5 0.3 1 9.2 0.3 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain Ring_hydroxyl_A PF00848.19 EMG47483.1 - 1.5e-20 74.1 0.0 3.1e-20 73.1 0.0 1.5 2 0 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EMG47483.1 - 1.1e-16 60.5 0.1 2.4e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Peptidase_M48_N PF16491.5 EMG47484.1 - 6.2e-62 208.7 8.1 6.2e-62 208.7 8.1 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EMG47484.1 - 1.3e-47 162.1 0.0 1.8e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 EMG47484.1 - 0.032 14.1 0.1 0.072 12.9 0.1 1.5 1 0 0 1 1 1 0 SprT-like family DUF2268 PF10026.9 EMG47484.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Glyco_transf_34 PF05637.12 EMG47485.1 - 1.5e-68 231.1 1.7 1.8e-68 230.9 1.7 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ARID PF01388.21 EMG47486.1 - 5.9e-13 49.3 0.0 5.9e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DUF999 PF06198.11 EMG47486.1 - 0.013 15.5 0.1 0.037 14.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF999) ASD2 PF08687.11 EMG47486.1 - 6.2 6.3 15.4 16 5.0 15.4 1.6 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 ATP-synt_E PF05680.12 EMG47487.1 - 1.2e-17 64.0 0.2 1.4e-17 63.8 0.2 1.0 1 0 0 1 1 1 1 ATP synthase E chain SpaA PF17802.1 EMG47487.1 - 0.027 14.8 0.0 0.037 14.3 0.0 1.1 1 0 0 1 1 1 0 Prealbumin-like fold domain Tox-REase-5 PF15648.6 EMG47487.1 - 0.041 14.4 0.0 0.045 14.3 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 Glyco_hydro_cc PF11790.8 EMG47487.1 - 0.12 11.9 0.2 0.15 11.6 0.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Otopetrin PF03189.13 EMG47487.1 - 0.14 10.9 0.0 0.15 10.9 0.0 1.0 1 0 0 1 1 1 0 Otopetrin Pex2_Pex12 PF04757.14 EMG47488.1 - 1.5e-37 129.4 6.0 2e-37 129.0 6.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 EMG47488.1 - 6e-10 39.3 10.3 1.1e-09 38.5 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EMG47488.1 - 1.2e-08 34.6 8.3 2.2e-08 33.8 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMG47488.1 - 3.1e-08 33.3 9.7 4.6e-08 32.8 9.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMG47488.1 - 7.1e-08 32.2 9.7 1.2e-07 31.4 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG47488.1 - 7.3e-06 25.9 7.2 2e-05 24.5 7.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EMG47488.1 - 1.2e-05 25.5 7.8 2.1e-05 24.7 7.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EMG47488.1 - 6.9e-05 22.6 12.0 0.00011 22.0 12.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EMG47488.1 - 0.00018 21.6 8.9 0.00037 20.6 8.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EMG47488.1 - 0.00027 20.8 5.0 0.00051 19.9 5.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain IBR PF01485.21 EMG47488.1 - 0.025 14.8 2.6 0.05 13.8 2.6 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 EMG47488.1 - 0.045 13.5 3.0 0.13 12.1 3.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 EMG47488.1 - 0.046 13.5 4.2 0.098 12.5 4.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EMG47488.1 - 0.15 11.9 7.7 0.32 10.8 7.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EMG47488.1 - 0.21 11.7 5.9 0.33 11.0 5.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EMG47488.1 - 0.32 11.2 8.0 0.61 10.3 8.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 SpoIIE PF07228.12 EMG47489.1 - 2.2e-19 70.1 0.0 3.4e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EMG47489.1 - 1.5e-06 28.1 0.1 0.0017 18.0 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EMG47489.1 - 2.9e-05 23.8 0.0 6.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SBF_like PF13593.6 EMG47490.1 - 6.5e-123 410.0 13.4 7.9e-123 409.7 13.4 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EMG47490.1 - 1.5e-10 41.1 1.6 1.5e-10 41.1 1.6 2.0 2 1 0 2 2 2 1 Sodium Bile acid symporter family Colicin_im PF03857.13 EMG47490.1 - 0.0048 16.9 0.7 0.013 15.5 0.3 1.9 2 0 0 2 2 2 1 Colicin immunity protein DUF4491 PF14898.6 EMG47490.1 - 9.5 6.7 11.3 0.77 10.2 5.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) FYVE PF01363.21 EMG47491.1 - 2.2e-23 82.2 25.4 4.4e-16 58.8 5.8 2.3 2 0 0 2 2 2 2 FYVE zinc finger Rbsn PF11464.8 EMG47491.1 - 4.1e-14 52.0 0.6 9.2e-14 50.9 0.6 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 EMG47491.1 - 0.0068 16.5 5.3 0.0068 16.5 5.3 3.1 3 0 0 3 3 3 1 AN1-like Zinc finger DUF3920 PF13058.6 EMG47491.1 - 0.045 13.9 1.5 0.19 11.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3920) JIP_LZII PF16471.5 EMG47491.1 - 0.47 10.7 3.4 21 5.4 0.9 3.3 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II PC4 PF02229.16 EMG47492.1 - 2.1e-21 75.3 0.2 3.2e-21 74.7 0.2 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Adeno_VII PF03228.14 EMG47492.1 - 0.014 16.0 0.1 0.019 15.6 0.1 1.1 1 0 0 1 1 1 0 Adenoviral core protein VII RNA_pol_3_Rpc31 PF11705.8 EMG47492.1 - 0.48 10.6 17.7 0.58 10.4 17.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1682 PF07946.14 EMG47492.1 - 3.2 6.9 12.3 3.8 6.6 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PBP_sp32 PF07222.12 EMG47492.1 - 4.8 6.6 12.7 6.6 6.1 12.7 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Aldo_ket_red PF00248.21 EMG47493.1 - 5.4e-48 163.7 0.0 6.5e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FCH PF00611.23 EMG47494.1 - 8.8e-12 45.2 0.3 8.8e-12 45.2 0.3 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EMG47494.1 - 1.5e-07 30.9 0.0 3.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMG47494.1 - 3.4e-05 23.6 0.0 7.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Exonuc_VII_L PF02601.15 EMG47494.1 - 2.9 7.4 7.4 2 7.9 4.9 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit muHD PF10291.9 EMG47495.1 - 1.2e-48 165.9 1.5 1.4e-48 165.6 0.1 1.8 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain Bap31 PF05529.12 EMG47496.1 - 1.2e-32 112.7 8.1 1.5e-32 112.3 8.1 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EMG47496.1 - 2.2e-11 43.5 6.2 3.5e-11 42.9 3.5 2.2 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF5082 PF16888.5 EMG47496.1 - 0.0081 16.4 0.9 0.013 15.8 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) CorA PF01544.18 EMG47497.1 - 6.4e-43 147.1 0.7 2.2e-23 83.0 0.0 3.6 2 1 0 3 3 3 3 CorA-like Mg2+ transporter protein DUF5089 PF17002.5 EMG47497.1 - 0.037 13.9 0.7 0.037 13.9 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5089) Holin_BhlA PF10960.8 EMG47497.1 - 0.081 12.9 2.3 6.5 6.8 0.3 3.2 3 0 0 3 3 3 0 BhlA holin family A_thal_3526 PF09713.10 EMG47497.1 - 0.13 12.5 0.1 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) OPT PF03169.15 EMG47498.1 - 4.5e-136 455.0 42.3 5.1e-136 454.8 42.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ammonium_transp PF00909.21 EMG47499.1 - 1.9e-118 395.7 30.0 2.2e-118 395.5 30.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1117 PF06547.12 EMG47499.1 - 0.074 13.6 0.4 0.15 12.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) DUF5512 PF17631.2 EMG47499.1 - 0.19 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5512) AA_permease_2 PF13520.6 EMG47500.1 - 1.4e-61 208.6 36.1 2.9e-61 207.6 36.1 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG47500.1 - 5e-08 32.0 30.7 5e-08 32.0 30.7 1.7 2 0 0 2 2 2 1 Amino acid permease zf-RING_5 PF14634.6 EMG47501.1 - 7.2e-08 32.3 7.0 1.4e-07 31.4 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMG47501.1 - 2.8e-06 27.2 4.9 2.8e-06 27.2 4.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EMG47501.1 - 9.8e-06 25.4 9.4 2.1e-05 24.3 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMG47501.1 - 5.9e-05 23.3 9.6 0.00019 21.7 9.6 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMG47501.1 - 0.00029 20.6 1.9 0.00029 20.6 1.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMG47501.1 - 0.0025 17.6 9.9 0.011 15.5 9.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMG47501.1 - 0.0042 16.9 14.3 0.84 9.5 9.1 3.2 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EMG47501.1 - 0.026 14.7 7.7 0.18 12.0 8.2 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING ETRAMP PF09716.10 EMG47501.1 - 0.57 10.3 0.0 0.57 10.3 0.0 3.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) ANTH PF07651.16 EMG47502.1 - 4.5e-64 216.1 4.3 4.5e-64 216.1 4.3 1.8 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 EMG47502.1 - 6.2e-08 32.7 0.7 2.2e-07 30.9 0.7 2.0 1 0 0 1 1 1 1 ENTH domain Pentapeptide PF00805.22 EMG47502.1 - 9.7e-07 28.3 0.0 7.2e-06 25.5 0.1 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EMG47502.1 - 3.3e-06 27.2 0.7 8.5e-06 25.9 0.7 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Cohesin_HEAT PF12765.7 EMG47502.1 - 0.21 11.9 0.0 0.57 10.5 0.0 1.7 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Rhodanese PF00581.20 EMG47503.1 - 3.3e-09 37.2 0.0 4.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain CTP_transf_like PF01467.26 EMG47504.1 - 5.9e-35 120.5 0.0 1.3e-34 119.4 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like RRN3 PF05327.11 EMG47504.1 - 0.024 13.2 6.2 0.037 12.6 6.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Trefoil PF00088.18 EMG47504.1 - 0.09 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Trefoil (P-type) domain CDC45 PF02724.14 EMG47504.1 - 6 5.0 15.2 0.038 12.3 6.7 1.6 2 0 0 2 2 2 0 CDC45-like protein MMM1 PF10296.9 EMG47505.1 - 2.3e-144 480.5 1.6 2.8e-144 480.2 1.6 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DUF1878 PF08963.10 EMG47505.1 - 0.056 13.9 0.6 0.19 12.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) IBN_N PF03810.19 EMG47506.1 - 2.9e-14 52.7 0.1 1.5e-13 50.4 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd3 PF12719.7 EMG47506.1 - 0.0033 16.7 0.4 0.35 10.0 0.0 2.6 1 1 1 2 2 2 2 Nuclear condensing complex subunits, C-term domain DUF4363 PF14276.6 EMG47506.1 - 0.062 13.4 1.0 3.7 7.7 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) RPAP3_C PF13877.6 EMG47506.1 - 0.14 12.7 2.0 0.72 10.4 0.0 3.2 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 SurE PF01975.17 EMG47507.1 - 1.1e-06 28.5 0.0 5.8e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Survival protein SurE SBF_like PF13593.6 EMG47508.1 - 3.9e-119 397.6 18.9 4.6e-119 397.4 18.9 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EMG47508.1 - 9.8e-10 38.4 5.7 9.8e-10 38.4 5.7 2.0 2 1 0 2 2 2 1 Sodium Bile acid symporter family KdgT PF03812.13 EMG47508.1 - 0.26 10.6 11.9 0.084 12.2 3.1 2.4 2 0 0 2 2 2 0 2-keto-3-deoxygluconate permease DUF4491 PF14898.6 EMG47508.1 - 7.3 7.1 13.0 0.26 11.7 5.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) LRR_8 PF13855.6 EMG47512.1 - 0.058 13.2 5.9 1.9 8.3 0.4 3.5 2 2 1 3 3 3 0 Leucine rich repeat Ion_trans_2 PF07885.16 EMG47513.1 - 4.7e-27 93.8 39.9 6.4e-17 61.3 8.1 4.1 4 0 0 4 4 4 2 Ion channel Metallophos_3 PF14582.6 EMG47513.1 - 0.12 11.6 2.3 0.21 10.9 2.3 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily CDC45 PF02724.14 EMG47513.1 - 1.3 7.3 5.2 1.8 6.8 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 EMG47513.1 - 4 7.6 14.8 8.9 6.5 14.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleoside_tran PF01733.18 EMG47514.1 - 1.4e-56 192.2 8.2 1.4e-56 192.2 8.2 1.7 2 0 0 2 2 2 1 Nucleoside transporter Aminotran_1_2 PF00155.21 EMG47516.1 - 4e-54 184.2 0.0 4.5e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMG47516.1 - 0.0035 15.9 0.1 0.012 14.2 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 EMG47516.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Allinase Ribosomal_S17 PF00366.20 EMG47517.1 - 2.1e-20 72.6 3.0 4.2e-20 71.6 3.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 CcmE PF03100.15 EMG47517.1 - 0.029 14.3 1.1 0.049 13.6 1.1 1.3 1 0 0 1 1 1 0 CcmE TPR_1 PF00515.28 EMG47518.1 - 3e-07 30.0 2.6 0.00012 21.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMG47518.1 - 4.1e-07 29.6 1.8 0.0057 16.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EMG47518.1 - 3.2e-06 27.2 0.0 1.7e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMG47518.1 - 0.0012 18.9 0.7 0.047 13.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMG47518.1 - 0.0039 16.8 2.0 0.023 14.3 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 EMG47518.1 - 0.051 14.4 0.0 13 7.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMG47518.1 - 0.13 12.9 0.2 47 4.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad1 PF02144.16 EMG47519.1 - 5.4e-46 156.9 10.3 7e-46 156.5 10.3 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_C PF02747.15 EMG47519.1 - 0.0036 17.5 2.0 0.0049 17.0 0.4 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain vATP-synt_AC39 PF01992.16 EMG47520.1 - 1.1e-101 340.7 1.7 1.2e-101 340.5 1.7 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Dor1 PF04124.12 EMG47521.1 - 5.4e-19 68.1 16.5 8.3e-19 67.4 16.5 1.2 1 0 0 1 1 1 1 Dor1-like family SNF2_N PF00176.23 EMG47522.1 - 1.9e-56 191.3 0.1 4.3e-56 190.1 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMG47522.1 - 1.5e-20 73.6 0.3 1.9e-19 70.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 EMG47522.1 - 3.7e-06 26.9 4.2 1e-05 25.4 4.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 EMG47522.1 - 5.8e-06 26.4 0.2 5.8e-06 26.4 0.2 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EMG47522.1 - 0.00032 20.5 3.5 0.0008 19.2 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMG47522.1 - 0.00041 20.6 6.7 0.00086 19.6 6.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EMG47522.1 - 0.00067 19.6 6.8 0.0017 18.3 6.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_5 PF17121.5 EMG47522.1 - 0.0013 18.6 2.1 0.0036 17.1 2.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMG47522.1 - 0.0033 17.6 4.3 0.0091 16.1 4.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FliJ PF02050.16 EMG47522.1 - 0.031 14.5 1.3 0.12 12.7 1.3 2.0 1 0 0 1 1 1 0 Flagellar FliJ protein zf-C3HC4 PF00097.25 EMG47522.1 - 0.035 14.0 6.7 0.092 12.6 6.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 EMG47522.1 - 0.042 14.3 3.7 0.12 12.8 3.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 EMG47522.1 - 0.13 12.4 4.0 0.32 11.1 4.0 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_4 PF14570.6 EMG47522.1 - 0.19 11.5 7.8 0.51 10.2 7.8 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EMG47522.1 - 0.35 10.8 8.8 25 4.8 9.2 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Beta-lactamase PF00144.24 EMG47523.1 - 6.6e-45 153.8 0.0 1e-44 153.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase TFR_dimer PF04253.15 EMG47524.1 - 9.7e-24 83.8 0.2 2e-23 82.8 0.2 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EMG47524.1 - 2.1e-07 30.8 0.0 4.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMG47524.1 - 0.00079 19.4 0.0 0.0027 17.7 0.0 1.9 1 1 0 1 1 1 1 PA domain DNA_ligase_OB PF03120.16 EMG47524.1 - 0.049 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain ChaC PF04752.12 EMG47525.1 - 3.1e-42 144.7 0.0 4.1e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Poty_PP PF08440.10 EMG47525.1 - 0.081 12.0 0.1 0.097 11.7 0.1 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein Na_H_Exchanger PF00999.21 EMG47527.1 - 7.6e-78 261.9 29.0 9.2e-78 261.7 29.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 EMG47527.1 - 4.4e-70 237.2 50.3 8.1e-70 236.3 50.3 1.3 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus CFEM PF05730.11 EMG47528.1 - 1.2e-10 41.3 5.4 1.8e-10 40.7 5.4 1.3 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_72 PF03198.14 EMG47529.1 - 2.8e-131 437.5 2.7 4.1e-131 436.9 2.7 1.2 1 0 0 1 1 1 1 Glucanosyltransferase FAD_binding_8 PF08022.12 EMG47530.1 - 1.2e-17 64.0 0.3 2.8e-17 62.8 0.3 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EMG47530.1 - 2.1e-17 63.7 0.1 3.3e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EMG47530.1 - 1.2e-14 54.5 14.5 2.6e-14 53.4 14.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Dam PF05869.11 EMG47530.1 - 0.051 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) CFEM PF05730.11 EMG47531.1 - 3.3e-11 43.1 4.0 5e-11 42.5 4.0 1.3 1 0 0 1 1 1 1 CFEM domain LAGLIDADG_3 PF14528.6 EMG47533.1 - 0.1 12.9 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 LAGLIDADG-like domain CFEM PF05730.11 EMG47535.1 - 2.4e-11 43.5 5.6 4.1e-11 42.8 5.6 1.4 1 0 0 1 1 1 1 CFEM domain Endomucin PF07010.12 EMG47537.1 - 5.4 6.9 32.3 6.5 6.7 32.3 1.1 1 0 0 1 1 1 0 Endomucin Lin-8 PF03353.15 EMG47537.1 - 6.2 6.3 19.1 7.7 6.0 19.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Asp-B-Hydro_N PF05279.11 EMG47537.1 - 6.8 6.7 20.7 8.6 6.4 20.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region IER PF05760.12 EMG47537.1 - 7.4 6.8 19.4 8.6 6.6 19.4 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) SSF PF00474.17 EMG47538.1 - 1.2e-23 83.7 18.2 1.2e-23 83.7 18.2 1.4 1 1 1 2 2 2 1 Sodium:solute symporter family AIM3 PF17096.5 EMG47539.1 - 0.0025 18.7 8.5 0.0025 18.7 8.5 8.0 4 3 2 6 6 6 2 Altered inheritance of mitochondria protein 3 SPC25 PF06703.11 EMG47540.1 - 3.9e-37 127.5 2.1 4.5e-37 127.3 2.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) IAT_beta PF11924.8 EMG47540.1 - 0.0018 17.8 0.2 0.5 9.7 0.0 2.1 2 0 0 2 2 2 2 Inverse autotransporter, beta-domain Hyr1 PF15789.5 EMG47543.1 - 7.9e-15 54.1 24.5 5.4e-10 38.6 9.5 2.1 2 0 0 2 2 2 2 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG47543.1 - 0.0026 18.2 6.8 0.1 13.1 0.8 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5628) Pput2613-deam PF14427.6 EMG47543.1 - 0.0047 16.8 0.6 0.017 15.0 0.2 1.7 1 1 1 2 2 2 1 Pput_2613-like deaminase HalOD2 PF18547.1 EMG47543.1 - 0.093 12.6 2.6 6.3 6.8 0.3 2.2 2 0 0 2 2 2 0 Halobacterial output domain 2 DUF3254 PF11630.8 EMG47543.1 - 0.15 12.2 1.9 4.9 7.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3254) PTPA PF03095.15 EMG47545.1 - 7.5e-80 268.6 0.0 9.2e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein zf-RING_2 PF13639.6 EMG47546.1 - 3.6e-07 30.4 7.9 8.7e-07 29.2 7.9 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EMG47546.1 - 2e-06 27.9 4.9 6.4e-06 26.3 4.9 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EMG47546.1 - 0.00011 22.5 5.9 0.00031 20.9 5.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EMG47546.1 - 0.00015 21.7 3.7 0.0004 20.4 3.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 EMG47546.1 - 0.0058 16.9 5.6 0.012 15.9 5.6 1.6 1 0 0 1 1 1 1 RING-like domain zf-C3HC4 PF00097.25 EMG47546.1 - 0.017 15.0 8.6 0.04 13.8 8.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EMG47546.1 - 0.018 14.6 4.6 0.039 13.6 4.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EMG47546.1 - 0.042 14.0 5.9 0.099 12.8 5.9 1.7 1 0 0 1 1 1 0 RING-variant domain Mt_ATP-synt_D PF05873.12 EMG47546.1 - 0.071 13.0 4.1 0.21 11.4 0.0 2.7 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) zf-C3HC4_2 PF13923.6 EMG47546.1 - 0.14 12.0 8.2 0.32 10.9 8.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMG47546.1 - 0.2 11.5 3.5 4.8 7.1 3.5 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EMG47546.1 - 0.31 10.9 6.9 3.3 7.6 0.6 3.2 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF2256 PF10013.9 EMG47546.1 - 0.61 10.2 3.5 2.2 8.5 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_1 PF00130.22 EMG47546.1 - 0.64 9.9 5.2 1.6 8.6 5.2 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 EMG47546.1 - 2.6 8.0 5.6 4.9 7.1 5.6 1.5 1 0 0 1 1 1 0 PHD-finger SHMT PF00464.19 EMG47547.1 - 4.3e-48 163.9 0.1 4.7e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 EMG47547.1 - 0.011 15.0 0.0 0.013 14.8 0.0 1.0 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aldo_ket_red PF00248.21 EMG47548.1 - 4e-45 154.3 0.0 6.4e-44 150.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Peptidase_S10 PF00450.22 EMG47549.1 - 4.7e-134 447.9 0.7 6.3e-134 447.5 0.7 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EMG47549.1 - 1.4e-38 132.2 2.0 2.8e-38 131.3 2.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide rRNA_proc-arch PF13234.6 EMG47551.1 - 2.5e-82 276.8 2.0 2.5e-82 276.8 2.0 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 EMG47551.1 - 5.2e-50 169.3 0.2 1.3e-49 168.1 0.2 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EMG47551.1 - 1.3e-19 70.6 0.8 1.2e-18 67.5 0.0 2.9 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG47551.1 - 8.6e-07 29.3 0.0 4.4e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EMG47551.1 - 0.04 14.2 0.1 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4047 PF13256.6 EMG47551.1 - 0.058 13.6 0.1 0.058 13.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) Fungal_TACC PF12709.7 EMG47551.1 - 0.07 13.6 3.3 0.65 10.5 0.4 3.0 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Com_YlbF PF06133.11 EMG47551.1 - 0.38 11.4 6.5 0.18 12.4 0.7 3.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Proteasome PF00227.26 EMG47552.1 - 5.4e-40 136.9 0.0 6.5e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF5427 PF10310.9 EMG47553.1 - 1.4e-107 360.6 21.3 2e-107 360.1 21.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5427) DUF922 PF06037.11 EMG47553.1 - 0.14 11.9 6.6 2.1 8.1 1.9 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) RNase_H2_suC PF08615.11 EMG47553.1 - 4.9 7.3 11.3 13 5.9 0.1 2.6 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SHMT PF00464.19 EMG47554.1 - 1.2e-47 162.4 0.1 1.4e-47 162.2 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 EMG47554.1 - 0.0086 15.4 0.0 0.01 15.2 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family BatD PF13584.6 EMG47555.1 - 0.0093 14.8 0.3 0.012 14.5 0.3 1.1 1 0 0 1 1 1 1 Oxygen tolerance OATP PF03137.20 EMG47555.1 - 0.018 13.4 0.1 0.018 13.4 0.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ASFV_J13L PF05568.11 EMG47555.1 - 0.038 13.8 0.0 0.045 13.5 0.0 1.3 1 1 0 1 1 1 0 African swine fever virus J13L protein EphA2_TM PF14575.6 EMG47555.1 - 0.072 14.0 0.0 0.09 13.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain YukC PF10140.9 EMG47555.1 - 0.098 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC FtsH_ext PF06480.15 EMG47555.1 - 0.11 12.9 0.1 0.2 12.0 0.1 1.7 1 1 0 1 1 1 0 FtsH Extracellular DUF4834 PF16118.5 EMG47555.1 - 0.13 13.3 0.0 0.17 12.9 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3533 PF12051.8 EMG47556.1 - 6.2e-107 357.8 19.8 7.7e-107 357.5 19.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.12 EMG47556.1 - 5.4 7.0 6.4 2.2 8.2 0.1 3.0 2 1 0 2 2 2 0 CDR ABC transporter Med16 PF11635.8 EMG47557.1 - 1.1e-242 807.2 14.6 1.3e-242 807.0 14.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Ago_N_1 PF18351.1 EMG47557.1 - 0.086 13.3 2.1 0.18 12.3 0.5 2.6 2 1 0 2 2 2 0 Fungal Argonaute N-terminal domain Tmemb_55A PF09788.9 EMG47557.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A DUF1955 PF09205.10 EMG47557.1 - 0.26 11.0 2.3 6.4 6.5 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1955) DDA1 PF10172.9 EMG47558.1 - 0.13 12.5 1.8 0.22 11.8 0.6 1.9 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase YEATS PF03366.16 EMG47559.1 - 9.3e-31 105.7 0.9 2.5e-30 104.3 0.9 1.8 1 0 0 1 1 1 1 YEATS family NMO PF03060.15 EMG47560.1 - 2e-41 142.5 0.0 5.5e-41 141.0 0.0 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EMG47560.1 - 1.3e-05 24.4 0.0 0.013 14.5 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EMG47560.1 - 0.049 13.1 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 EMG47560.1 - 0.071 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Isochorismatase PF00857.20 EMG47561.1 - 7.6e-20 71.8 0.1 3.6e-18 66.4 0.1 2.0 1 1 0 1 1 1 1 Isochorismatase family Metallophos PF00149.28 EMG47562.1 - 2.4e-10 41.3 1.3 3.7e-10 40.7 1.3 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMG47562.1 - 0.00028 21.1 0.0 0.00046 20.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RabGAP-TBC PF00566.18 EMG47563.1 - 1.7e-34 119.4 26.7 2.3e-31 109.1 13.2 3.1 2 1 1 3 3 3 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 EMG47563.1 - 2.7e-06 27.0 0.4 1.8e-05 24.3 0.4 2.1 2 0 0 2 2 2 1 Rab-binding domain (RBD) Sec7 PF01369.20 EMG47564.1 - 2.5e-24 86.0 1.7 6.2e-24 84.7 1.7 1.7 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EMG47564.1 - 0.011 16.0 1.3 0.058 13.8 0.0 2.6 2 1 1 3 3 3 0 Pleckstrin homology domain SelP_N PF04592.14 EMG47564.1 - 0.25 10.7 16.0 0.69 9.3 16.0 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3533 PF12051.8 EMG47565.1 - 2.7e-101 339.3 20.3 3.2e-101 339.0 20.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) MatE PF01554.18 EMG47566.1 - 7.9e-63 210.9 34.2 1.1e-35 122.7 12.6 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EMG47566.1 - 2e-05 24.7 11.5 2e-05 24.7 11.5 3.9 2 2 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Bystin PF05291.11 EMG47567.1 - 2.1e-122 408.0 0.6 4e-122 407.1 0.6 1.4 1 0 0 1 1 1 1 Bystin PI-PLC-X PF00388.19 EMG47567.1 - 4.2e-58 195.1 0.0 1.4e-57 193.3 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EMG47567.1 - 5.3e-46 155.7 0.1 2.3e-45 153.6 0.1 2.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 EMG47567.1 - 0.0072 16.8 0.3 0.0072 16.8 0.3 3.6 2 1 2 4 4 4 1 Phosphoinositide-specific phospholipase C, efhand-like His_biosynth PF00977.21 EMG47568.1 - 1.8e-45 155.2 0.1 1.2e-44 152.5 0.1 2.4 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EMG47568.1 - 6.3e-15 55.4 0.0 1.1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EMG47568.1 - 1.9e-05 24.4 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiG PF05690.14 EMG47568.1 - 0.0023 17.3 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Methyltransf_25 PF13649.6 EMG47569.1 - 0.00017 22.2 0.0 0.002 18.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG47569.1 - 0.0014 19.2 0.0 0.0033 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EMG47569.1 - 0.067 11.7 0.7 0.12 10.9 0.0 1.7 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MRI PF15325.6 EMG47569.1 - 7.2 7.8 7.7 23 6.2 7.7 1.8 1 0 0 1 1 1 0 Modulator of retrovirus infection LRR_4 PF12799.7 EMG47570.1 - 1.2e-08 35.0 27.8 0.0045 17.4 4.3 9.4 4 3 4 9 9 9 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMG47570.1 - 3.6e-07 29.7 3.5 0.62 10.3 0.0 7.0 6 1 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.6 EMG47570.1 - 1.9e-05 24.3 15.5 0.045 13.5 3.7 5.8 5 2 1 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 EMG47570.1 - 1.9 9.4 26.0 4.7 8.2 0.2 8.5 9 3 1 10 10 10 0 Leucine Rich Repeat tRNA-synt_2 PF00152.20 EMG47571.1 - 1.2e-78 264.4 0.0 1.5e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMG47571.1 - 2.3e-07 30.7 0.1 5.7e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PHP PF02811.19 EMG47572.1 - 2.2e-14 54.1 0.1 4.1e-14 53.2 0.1 1.5 2 0 0 2 2 2 1 PHP domain SpoU_methylase PF00588.19 EMG47572.1 - 0.2 11.8 0.0 0.44 10.7 0.0 1.6 1 1 0 1 1 1 0 SpoU rRNA Methylase family ProRS-C_1 PF09180.11 EMG47573.1 - 3.8e-27 94.3 1.4 8.3e-27 93.2 1.4 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EMG47573.1 - 4.7e-19 68.3 0.5 1.8e-18 66.4 0.0 2.3 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EMG47573.1 - 1.5e-18 67.4 0.0 3.3e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 EMG47573.1 - 8.2e-05 22.7 0.2 0.00017 21.7 0.2 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Ribosomal_60s PF00428.19 EMG47573.1 - 1.8 9.2 13.8 0.38 11.4 7.0 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein tRNA-synt_2 PF00152.20 EMG47574.1 - 2.4e-91 306.1 0.3 1.3e-90 303.7 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMG47574.1 - 3.5e-13 49.3 0.1 7.4e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.11 EMG47574.1 - 0.0036 16.8 0.0 0.0068 15.9 0.0 1.4 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain tRNA_anti_2 PF13742.6 EMG47574.1 - 0.0045 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 EMG47574.1 - 0.035 14.1 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Lyase_1 PF00206.20 EMG47575.1 - 4e-99 331.9 0.0 6e-99 331.4 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EMG47575.1 - 9.1e-23 80.8 0.0 2e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Amidase PF01425.21 EMG47576.1 - 4.7e-91 306.0 0.0 6.1e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Mannosyl_trans3 PF11051.8 EMG47577.1 - 1.2e-81 274.1 0.9 2.6e-81 273.0 0.9 1.6 1 0 0 1 1 1 1 Mannosyltransferase putative BRICHOS PF04089.14 EMG47577.1 - 0.1 12.8 0.2 0.46 10.8 0.2 2.1 2 0 0 2 2 2 0 BRICHOS domain Mannosyl_trans3 PF11051.8 EMG47578.1 - 5.2e-65 219.5 0.5 9.5e-65 218.7 0.0 1.7 2 0 0 2 2 2 1 Mannosyltransferase putative DUF4508 PF14969.6 EMG47578.1 - 0.13 12.5 1.1 0.4 11.0 0.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) Peptidase_M16_C PF05193.21 EMG47579.1 - 2.9e-17 63.3 0.4 2.7e-13 50.3 0.1 3.5 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EMG47579.1 - 2e-09 37.6 0.0 6e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Bromodomain PF00439.25 EMG47580.1 - 6.8e-17 61.3 0.2 2e-16 59.8 0.2 1.9 1 0 0 1 1 1 1 Bromodomain zf-Tim10_DDP PF02953.15 EMG47581.1 - 7.1e-22 76.8 4.9 9.9e-22 76.4 4.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1178 PF06676.11 EMG47581.1 - 0.025 15.0 0.2 0.032 14.6 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Tam41_Mmp37 PF09139.11 EMG47581.1 - 0.047 13.1 0.5 0.048 13.1 0.5 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial E_Pc_C PF06752.12 EMG47581.1 - 3.7 7.6 8.5 0.11 12.6 0.6 1.9 1 1 1 2 2 2 0 Enhancer of Polycomb C-terminus Epimerase PF01370.21 EMG47582.1 - 0.0032 17.0 0.0 0.0035 16.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EMG47582.1 - 0.0081 16.3 0.0 0.0095 16.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EMG47582.1 - 0.012 16.0 0.1 0.017 15.6 0.1 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FAM76 PF16046.5 EMG47584.1 - 0.013 14.9 3.2 0.017 14.5 3.2 1.2 1 0 0 1 1 1 0 FAM76 protein Abhydrolase_1 PF00561.20 EMG47585.1 - 2.7e-21 76.4 0.0 6.3e-21 75.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG47585.1 - 2.3e-14 53.2 0.0 2.6e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMG47585.1 - 1.2e-13 52.2 0.0 2.2e-13 51.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EMG47585.1 - 0.002 18.1 0.0 0.0058 16.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EMG47585.1 - 0.0055 16.3 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Isochorismatase PF00857.20 EMG47586.1 - 2e-20 73.7 0.3 6.4e-20 72.0 0.3 1.8 1 1 0 1 1 1 1 Isochorismatase family Isy1 PF06246.12 EMG47587.1 - 2.1e-55 188.0 1.5 2.5e-55 187.8 1.5 1.0 1 0 0 1 1 1 1 Isy1-like splicing family CDC13_N PF16853.5 EMG47587.1 - 0.049 13.1 0.9 0.063 12.8 0.9 1.1 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus NUC153 PF08159.12 EMG47588.1 - 3.2e-14 52.4 0.9 6.2e-14 51.5 0.9 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EMG47588.1 - 0.0015 19.3 0.5 4.3 8.4 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF1977 PF09320.11 EMG47589.1 - 4e-30 104.2 0.8 4e-30 104.2 0.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EMG47589.1 - 6.1e-24 83.9 1.6 8.1e-24 83.5 0.3 1.8 2 0 0 2 2 2 1 DnaJ domain FAP PF07174.11 EMG47591.1 - 0.93 8.9 22.1 1 8.7 22.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) NAPRTase PF04095.16 EMG47593.1 - 5e-68 229.3 0.3 6.3e-68 229.0 0.3 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EMG47593.1 - 9.7e-34 116.4 0.3 2.3e-33 115.2 0.3 1.7 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain STT3_PglB_C PF18527.1 EMG47593.1 - 0.087 12.9 0.8 2.1 8.5 0.3 2.6 2 0 0 2 2 2 0 STT3/PglB C-terminal beta-barrel domain CAF1C_H4-bd PF12265.8 EMG47594.1 - 2.6e-19 69.2 0.4 1.6e-18 66.7 0.2 2.5 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EMG47594.1 - 2.9e-13 50.1 12.0 0.017 16.0 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG47594.1 - 0.0057 16.9 0.1 4.1 7.8 0.0 3.0 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Vps55 PF04133.14 EMG47595.1 - 8.5e-34 116.0 7.4 1e-33 115.8 7.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2108 PF09881.9 EMG47595.1 - 0.0058 16.6 0.1 0.0058 16.6 0.1 2.9 3 1 1 4 4 4 1 Predicted membrane protein (DUF2108) CPBP PF02517.16 EMG47595.1 - 0.048 14.0 4.5 0.11 12.9 4.5 1.7 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease TctB PF07331.11 EMG47595.1 - 0.2 11.9 8.4 0.33 11.2 8.5 1.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family THUMP PF02926.17 EMG47596.1 - 2.2e-18 66.7 1.0 3e-18 66.3 0.5 1.5 1 1 0 1 1 1 1 THUMP domain KH_10 PF17905.1 EMG47596.1 - 0.0021 18.5 0.2 0.0074 16.7 0.0 1.9 2 0 0 2 2 2 1 GLD-3 KH domain 5 RF-1 PF00472.20 EMG47596.1 - 0.0077 16.2 1.2 0.016 15.1 0.3 1.9 2 0 0 2 2 2 1 RF-1 domain Peptidase_C1 PF00112.23 EMG47596.1 - 0.017 15.2 0.3 0.11 12.6 0.0 2.1 1 1 2 3 3 3 0 Papain family cysteine protease HSP70 PF00012.20 EMG47598.1 - 6.2e-218 724.8 12.9 7.7e-218 724.5 12.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMG47598.1 - 3.1e-17 62.4 4.4 1.2e-15 57.2 1.7 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EMG47598.1 - 0.0007 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EMG47598.1 - 0.0058 17.0 2.5 0.053 13.9 0.1 3.4 4 1 0 4 4 4 1 Cell division protein FtsA baeRF_family7 PF18849.1 EMG47598.1 - 0.023 14.9 0.6 0.047 13.9 0.6 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 DUF1464 PF07318.12 EMG47598.1 - 0.046 12.9 0.1 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) Ntox14 PF15522.6 EMG47598.1 - 0.074 12.5 0.1 0.97 8.8 0.0 2.2 2 0 0 2 2 2 0 Novel toxin 14 StbA PF06406.11 EMG47598.1 - 0.46 9.7 3.7 2 7.5 0.2 2.6 2 1 1 3 3 3 0 StbA protein Proteasome PF00227.26 EMG47599.1 - 1.2e-47 161.9 0.1 1.5e-47 161.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMG47599.1 - 5.8e-11 41.9 0.1 9.8e-11 41.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature IBN_N PF03810.19 EMG47600.1 - 4.3e-13 49.0 0.2 3.2e-12 46.2 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EMG47600.1 - 0.00016 21.7 0.5 0.00016 21.7 0.5 3.4 4 0 0 4 4 4 1 Exportin 1-like protein Cnd1 PF12717.7 EMG47600.1 - 1.2 9.1 8.4 5 7.1 0.1 4.7 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Ribosomal_60s PF00428.19 EMG47601.1 - 0.00039 20.9 0.2 0.00055 20.5 0.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Mad3_BUB1_II PF08171.11 EMG47601.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 MAM33 PF02330.16 EMG47602.1 - 2.1e-36 125.9 4.1 2.7e-36 125.5 4.1 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cyclin_N PF00134.23 EMG47603.1 - 6.4e-45 152.0 0.1 1.3e-44 151.0 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EMG47603.1 - 7.4e-35 119.6 0.0 2.4e-34 118.0 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain NOA36 PF06524.12 EMG47603.1 - 0.98 8.7 8.6 1.9 7.7 8.6 1.4 1 0 0 1 1 1 0 NOA36 protein Flocculin_t3 PF13928.6 EMG47604.1 - 3.9e-06 27.3 15.9 3.9e-06 27.3 15.9 3.4 3 1 0 3 3 3 1 Flocculin type 3 repeat ICAP-1_inte_bdg PF10480.9 EMG47604.1 - 0.28 11.1 9.0 0.69 9.9 9.0 1.6 1 0 0 1 1 1 0 Beta-1 integrin binding protein Med13_C PF06333.12 EMG47605.1 - 0.16 11.2 4.6 0.2 10.9 4.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain OGG_N PF07934.12 EMG47606.1 - 4.3e-34 117.2 2.4 9.1e-34 116.2 1.1 1.9 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EMG47606.1 - 9.3e-19 67.9 0.0 1.6e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EMG47606.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Hyr1 PF15789.5 EMG47607.1 - 4.7e-22 77.3 68.8 1.3e-08 34.2 17.3 4.8 4 2 0 4 4 4 3 Hyphally regulated cell wall GPI-anchored protein 1 Imm53 PF15580.6 EMG47607.1 - 0.00021 21.0 0.0 9.4 6.0 0.0 3.1 3 0 0 3 3 3 1 Immunity protein 53 Pab87_oct PF13969.6 EMG47607.1 - 0.00032 20.7 2.2 0.078 13.1 0.4 2.8 1 1 2 3 3 3 2 Pab87 octamerisation domain FTP PF07504.13 EMG47607.1 - 0.0033 17.2 8.0 7.1 6.5 0.3 4.5 3 3 2 5 5 5 3 Fungalysin/Thermolysin Propeptide Motif DUF3872 PF12988.7 EMG47607.1 - 0.0042 16.9 0.1 13 5.6 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3872) TPM_phosphatase PF04536.14 EMG47607.1 - 0.0068 16.6 5.9 0.16 12.1 0.7 2.4 1 1 1 2 2 2 2 TPM domain MHC_I_2 PF14586.6 EMG47607.1 - 0.0076 16.1 0.3 5.7 6.8 0.0 2.8 1 1 2 3 3 3 1 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 PPV_E2_C PF00511.17 EMG47607.1 - 0.066 13.4 11.8 2.8 8.2 0.4 3.1 1 1 1 3 3 3 0 E2 (early) protein, C terminal DUF3509 PF12021.8 EMG47607.1 - 0.12 12.1 0.8 41 4.0 0.0 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF3509) NIBRIN_BRCT_II PF16508.5 EMG47607.1 - 0.17 12.2 1.8 16 5.9 0.1 2.6 1 1 2 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein DUF5052 PF16475.5 EMG47607.1 - 0.56 9.8 13.2 7 6.2 2.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF5052) Glyco_hyd_65N_2 PF14498.6 EMG47607.1 - 1 9.1 9.9 44 3.8 9.9 2.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain FliC PF12445.8 EMG47607.1 - 1.8 8.9 41.5 5.4 7.4 7.2 3.1 3 0 0 3 3 3 0 Flagellin protein DUF4871 PF16167.5 EMG47607.1 - 2.1 8.4 14.0 2.4 8.2 2.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4871) DUF2888 PF11135.8 EMG47607.1 - 2.4 8.1 10.0 14 5.7 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2888) PGM1_C PF18105.1 EMG47607.1 - 3.9 7.1 9.1 40 3.8 0.4 3.4 3 0 0 3 3 3 0 PGM1 C-terminal domain DUF4847 PF16139.5 EMG47607.1 - 4.8 7.1 9.8 18 5.3 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4847) Hyphal_reg_CWP PF11765.8 EMG47609.1 - 3.6e-116 387.7 15.8 4.1e-116 387.5 15.8 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal UQ_con PF00179.26 EMG47610.1 - 1.2e-48 164.3 0.0 1.4e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMG47610.1 - 0.00016 21.4 0.3 0.00049 19.8 0.0 1.7 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 EMG47610.1 - 0.0072 16.6 0.0 0.013 15.8 0.0 1.6 1 1 0 1 1 1 1 RWD domain Imm42 PF15593.6 EMG47610.1 - 0.06 13.8 0.2 0.077 13.5 0.2 1.2 1 0 0 1 1 1 0 Immunity protein 42 SPRY PF00622.28 EMG47611.1 - 2.6e-11 43.7 0.1 8.4e-11 42.0 0.1 2.0 1 0 0 1 1 1 1 SPRY domain COX4 PF02936.14 EMG47611.1 - 3.7e-05 23.8 0.5 0.00032 20.7 0.3 2.6 2 0 0 2 2 2 1 Cytochrome c oxidase subunit IV Ndc1_Nup PF09531.10 EMG47611.1 - 8.1 5.0 13.5 16 4.0 13.5 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ThrE PF06738.12 EMG47612.1 - 4.7e-67 225.9 17.5 3.1e-64 216.7 5.6 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EMG47612.1 - 5.7e-09 36.2 9.6 5.7e-09 36.2 9.6 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE ANTH PF07651.16 EMG47613.1 - 2.6e-78 262.8 0.0 2.6e-78 262.8 0.0 3.2 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 EMG47613.1 - 4.6e-53 179.6 7.3 4.6e-53 179.6 7.3 5.8 4 2 1 5 5 5 1 I/LWEQ domain Spc7 PF08317.11 EMG47613.1 - 0.00084 18.3 18.8 0.00084 18.3 18.8 5.0 2 2 2 5 5 5 1 Spc7 kinetochore protein PSII_Pbs27 PF13326.6 EMG47613.1 - 9.1 6.6 10.2 1.2 9.4 2.5 3.0 3 0 0 3 3 3 0 Photosystem II Pbs27 Rer1 PF03248.13 EMG47614.1 - 2.4e-80 268.3 3.4 2.7e-80 268.1 3.4 1.0 1 0 0 1 1 1 1 Rer1 family Halogen_Hydrol PF10112.9 EMG47614.1 - 0.1 12.6 0.3 5 7.1 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein COX7C PF02935.16 EMG47614.1 - 0.28 11.5 0.0 0.28 11.5 0.0 2.8 2 2 2 4 4 4 0 Cytochrome c oxidase subunit VIIc Ribosomal_L27_C PF18471.1 EMG47615.1 - 6.9e-43 146.8 9.8 8.4e-43 146.5 9.8 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Ribosomal_L27 PF01016.19 EMG47615.1 - 5.1e-31 106.5 0.1 9.1e-31 105.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Spore_III_AB PF09548.10 EMG47615.1 - 0.012 15.7 1.2 0.012 15.7 1.2 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) LIN52 PF10044.9 EMG47615.1 - 0.023 15.4 0.5 0.074 13.8 0.5 1.8 1 0 0 1 1 1 0 Retinal tissue protein ABC_trans_N PF14510.6 EMG47615.1 - 0.084 13.5 0.1 0.31 11.7 0.1 2.1 1 1 0 1 1 1 0 ABC-transporter N-terminal Peptidase_S46 PF10459.9 EMG47615.1 - 0.64 8.6 6.6 0.86 8.2 6.6 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF4259 PF14078.6 EMG47616.1 - 5.6e-37 127.5 4.6 6.5e-37 127.3 4.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4259) PG_binding_4 PF12229.8 EMG47616.1 - 0.011 16.0 0.8 0.025 14.8 0.7 1.6 1 1 0 1 1 1 0 Putative peptidoglycan binding domain Pyr_redox PF00070.27 EMG47616.1 - 0.073 13.6 0.0 7.5 7.2 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Haem_degrading PF03928.14 EMG47617.1 - 5.9e-30 103.8 0.0 6.8e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Haem-degrading Rcd1 PF04078.13 EMG47618.1 - 3.6e-115 383.7 4.8 4.8e-115 383.3 4.8 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like RasGEF_N PF00618.20 EMG47618.1 - 0.048 13.9 2.4 0.63 10.3 0.8 2.7 2 1 0 2 2 2 0 RasGEF N-terminal motif SUIM_assoc PF16619.5 EMG47618.1 - 0.049 13.7 0.1 0.049 13.7 0.1 3.7 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 T3SS_needle_E PF08988.10 EMG47618.1 - 1.9 8.7 10.2 0.44 10.7 0.3 3.3 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle NOC3p PF07540.11 EMG47619.1 - 2.1e-28 98.6 0.3 2.1e-28 98.6 0.3 2.9 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 EMG47619.1 - 5.2e-21 75.4 0.0 5.2e-21 75.4 0.0 2.7 3 0 0 3 3 3 1 CBF/Mak21 family Vta1 PF04652.16 EMG47619.1 - 0.54 10.2 7.1 4.5 7.2 0.2 2.8 2 0 0 2 2 2 0 Vta1 like Lsr2 PF11774.8 EMG47619.1 - 3 8.0 6.9 1.6 8.9 0.6 2.5 2 0 0 2 2 2 0 Lsr2 Peptidase_S8 PF00082.22 EMG47620.1 - 1.8e-31 109.6 9.0 3.1e-31 108.8 9.0 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMG47620.1 - 9.6e-14 51.8 0.0 1.9e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 UQ_con PF00179.26 EMG47621.1 - 6.1e-40 136.1 0.0 9.6e-40 135.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMG47621.1 - 0.015 15.0 0.0 0.057 13.1 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B Prothymosin PF03247.14 EMG47621.1 - 0.38 11.2 17.9 0.71 10.4 17.9 1.6 1 0 0 1 1 1 0 Prothymosin/parathymosin family Pox_Ag35 PF03286.14 EMG47621.1 - 5.3 6.8 8.8 8.1 6.2 8.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CAF1A PF12253.8 EMG47621.1 - 7.7 6.8 21.4 14 5.9 21.4 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A SLM4 PF16818.5 EMG47622.1 - 2.1e-13 50.6 5.1 1.2e-12 48.1 5.1 2.0 1 1 0 1 1 1 1 Protein SLM4 Complex1_49kDa PF00346.19 EMG47623.1 - 3.9e-119 396.7 0.0 5.2e-119 396.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EMG47623.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase AhpC-TSA PF00578.21 EMG47624.1 - 2e-08 34.2 0.0 2.2e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family DUF844 PF05815.11 EMG47624.1 - 0.024 13.8 0.0 0.027 13.7 0.0 1.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Redoxin PF08534.10 EMG47624.1 - 0.039 13.7 0.0 0.04 13.6 0.0 1.0 1 0 0 1 1 1 0 Redoxin Proteasome PF00227.26 EMG47625.1 - 2.3e-52 177.3 0.0 2.7e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMG47625.1 - 8.8e-08 31.7 0.7 1.4e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature NOA36 PF06524.12 EMG47625.1 - 0.54 9.5 8.0 0.71 9.1 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein tRNA-synt_2 PF00152.20 EMG47626.1 - 7.1e-66 222.4 0.0 9.2e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMG47626.1 - 1.7e-08 34.3 0.0 2.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMG47626.1 - 8.3e-07 28.7 0.1 0.0021 17.6 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 EMG47626.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain HALZ PF02183.18 EMG47627.1 - 0.0014 18.8 37.9 0.0031 17.7 0.2 6.9 7 0 0 7 7 7 3 Homeobox associated leucine zipper DUF1192 PF06698.11 EMG47627.1 - 0.18 11.9 6.0 3.8 7.6 0.9 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Mto2_bdg PF12808.7 EMG47627.1 - 0.46 10.8 22.1 0.17 12.2 5.5 4.5 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Fib_alpha PF08702.10 EMG47627.1 - 7.6 6.7 48.9 0.29 11.3 8.7 5.9 4 2 1 5 5 5 0 Fibrinogen alpha/beta chain family eIF2A PF08662.11 EMG47628.1 - 2.2e-37 128.8 0.7 4.5e-34 118.0 0.6 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EMG47628.1 - 6.4e-08 32.3 0.0 1.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 EMG47628.1 - 0.15 12.3 0.2 35 4.8 0.0 3.7 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 EMG47629.1 - 1.9e-34 117.3 0.1 3.7e-34 116.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 EMG47629.1 - 1.7e-20 72.9 0.8 1.6e-06 28.7 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_4 PF16300.5 EMG47629.1 - 7e-19 67.5 0.2 1.4e-18 66.5 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat Nup160 PF11715.8 EMG47629.1 - 1e-06 27.7 0.1 0.0031 16.3 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EMG47629.1 - 2.8e-06 27.5 0.0 0.00036 20.8 0.0 3.4 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMG47629.1 - 0.0004 19.5 0.0 0.034 13.1 0.0 2.5 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RasGAP_C PF03836.15 EMG47630.1 - 6.9e-42 142.8 7.7 6.9e-42 142.8 7.7 3.3 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.19 EMG47630.1 - 1.7e-37 129.2 0.8 1.7e-37 129.2 0.8 2.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 EMG47630.1 - 2.8e-11 43.5 0.8 9.8e-11 41.8 0.8 2.1 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 EMG47630.1 - 1.6e-08 33.6 14.0 0.15 11.9 0.0 9.5 10 0 0 10 10 10 3 IQ calmodulin-binding motif Mis14 PF08641.12 EMG47631.1 - 1.5e-20 73.9 7.6 2.9e-20 72.9 7.6 1.5 1 0 0 1 1 1 1 Kinetochore protein Mis14 like DUF3375 PF11855.8 EMG47631.1 - 0.011 14.7 2.1 0.014 14.3 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) INTS5_N PF14837.6 EMG47631.1 - 0.046 13.3 2.6 0.097 12.3 0.8 2.1 1 1 0 2 2 2 0 Integrator complex subunit 5 N-terminus NDUFB10 PF10249.9 EMG47631.1 - 0.048 14.2 1.9 0.11 13.0 1.5 1.8 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 Terminase_2 PF03592.16 EMG47631.1 - 0.2 12.1 6.5 4.9 7.6 3.2 2.2 1 1 0 2 2 2 0 Terminase small subunit Focal_AT PF03623.13 EMG47631.1 - 0.23 11.4 6.9 0.09 12.8 1.5 2.7 2 1 1 3 3 3 0 Focal adhesion targeting region ATP-synt_C PF00137.21 EMG47632.1 - 3.4e-31 107.4 32.7 1.9e-19 69.7 9.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TIP49 PF06068.13 EMG47633.1 - 8.6e-158 525.1 2.2 1.2e-157 524.6 2.2 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EMG47633.1 - 1.3e-23 82.9 0.8 4.7e-23 81.1 0.7 2.1 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EMG47633.1 - 1.2e-07 32.2 2.0 0.00026 21.4 0.1 3.0 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMG47633.1 - 4.8e-07 29.7 2.2 0.0011 18.7 0.1 2.6 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EMG47633.1 - 0.0008 18.8 1.4 0.0011 18.4 0.2 1.7 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EMG47633.1 - 0.00086 19.7 0.4 0.0032 17.9 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EMG47633.1 - 0.0013 19.0 1.3 0.013 15.8 0.5 2.7 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EMG47633.1 - 0.0027 17.1 1.4 0.04 13.3 0.5 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EMG47633.1 - 0.0043 17.3 0.1 0.46 10.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 EMG47633.1 - 0.0068 16.7 0.1 0.019 15.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMG47633.1 - 0.028 14.4 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EMG47633.1 - 0.032 13.9 0.1 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 EMG47633.1 - 0.041 13.3 0.8 2.1 7.7 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Cas9_b_hairpin PF17893.1 EMG47633.1 - 0.051 13.4 0.0 1.9 8.3 0.0 2.8 3 0 0 3 3 3 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain AAA_25 PF13481.6 EMG47633.1 - 0.069 12.7 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMG47633.1 - 0.081 13.5 0.1 0.34 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain PFK PF00365.20 EMG47634.1 - 9.1e-181 599.4 6.4 9.8e-103 343.4 2.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase SHOCT PF09851.9 EMG47634.1 - 0.0031 17.2 0.1 0.011 15.5 0.1 1.9 1 0 0 1 1 1 1 Short C-terminal domain DAGK_cat PF00781.24 EMG47634.1 - 0.12 12.0 0.1 0.39 10.4 0.1 1.9 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain UVR PF02151.19 EMG47634.1 - 0.17 11.7 0.2 0.47 10.3 0.2 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif DHHC PF01529.20 EMG47635.1 - 5.3e-33 114.0 9.9 5.3e-33 114.0 9.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase RE_MjaI PF09568.10 EMG47636.1 - 0.0015 18.4 0.4 0.0038 17.1 0.0 1.8 2 1 0 2 2 2 1 MjaI restriction endonuclease AhpC-TSA PF00578.21 EMG47637.1 - 4.6e-07 29.8 0.1 4.8e-07 29.7 0.1 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMG47637.1 - 0.0072 16.0 0.0 0.0072 16.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin PALP PF00291.25 EMG47638.1 - 4.2e-68 229.9 0.0 5.1e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Latrotoxin_C PF15658.6 EMG47638.1 - 0.11 12.3 0.0 5 6.9 0.0 2.2 2 0 0 2 2 2 0 Latrotoxin C-terminal domain Xpo1 PF08389.12 EMG47639.1 - 3.8e-32 111.4 0.5 3.8e-32 111.4 0.5 4.5 5 0 0 5 5 5 2 Exportin 1-like protein Asp PF00026.23 EMG47640.1 - 1.4e-25 90.4 0.0 9.4e-25 87.7 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMG47640.1 - 0.0088 16.3 0.1 0.0088 16.3 0.1 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TPT PF03151.16 EMG47641.1 - 2.6e-15 56.6 27.1 3.4e-15 56.2 27.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EMG47641.1 - 1e-11 44.6 23.6 1.3e-11 44.3 23.6 1.2 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EMG47641.1 - 1.8e-11 43.8 23.9 1.8e-11 43.8 23.9 1.3 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 EMG47641.1 - 5.4e-06 26.6 44.0 1.1e-05 25.6 21.6 2.6 2 1 0 2 2 2 2 EamA-like transporter family Sec1 PF00995.23 EMG47642.1 - 5.6e-87 293.3 4.4 8.3e-87 292.7 4.4 1.2 1 0 0 1 1 1 1 Sec1 family DUF3694 PF12473.8 EMG47642.1 - 0.0023 18.6 0.0 0.0057 17.3 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein zf-H2C2_2 PF13465.6 EMG47643.1 - 7.7e-07 29.3 12.9 1.1e-05 25.6 1.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EMG47643.1 - 2e-06 27.9 13.6 0.00018 21.8 3.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG47643.1 - 0.0024 18.6 11.5 0.083 13.8 2.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EMG47643.1 - 0.0062 17.2 0.8 0.019 15.6 0.0 2.2 3 0 0 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 EMG47643.1 - 0.0072 16.7 7.9 0.16 12.4 1.1 3.0 2 1 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EMG47643.1 - 0.26 11.3 13.2 3.4 7.8 5.6 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMG47643.1 - 0.32 11.3 3.5 3.2 8.1 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TFIIA PF03153.13 EMG47643.1 - 1.9 8.4 22.9 2.6 8.0 22.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box-like PF12937.7 EMG47645.1 - 2.7e-07 30.3 0.6 6.6e-07 29.1 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMG47645.1 - 1.8e-05 24.5 0.6 4.8e-05 23.1 0.6 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EMG47645.1 - 2.4e-05 24.2 0.3 5.7e-05 23.0 0.3 1.7 1 0 0 1 1 1 1 F-box TauD PF02668.16 EMG47646.1 - 2.4e-47 162.0 0.0 3.3e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EMG47646.1 - 4.5e-06 27.2 0.0 1.7e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EMG47646.1 - 0.0088 15.2 0.2 0.024 13.7 0.0 1.7 2 0 0 2 2 2 1 CsiD Lipin_N PF04571.14 EMG47646.1 - 0.014 15.3 0.1 0.65 10.0 0.0 2.6 2 0 0 2 2 2 0 lipin, N-terminal conserved region 2OG-FeII_Oxy_3 PF13640.6 EMG47646.1 - 0.064 14.2 0.0 0.16 12.9 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily SH2_2 PF14633.6 EMG47647.1 - 3.3e-70 235.9 0.3 3.3e-70 235.9 0.3 2.0 2 0 0 2 2 2 1 SH2 domain HTH_44 PF14641.6 EMG47647.1 - 9.8e-35 119.5 2.0 9.8e-35 119.5 2.0 2.3 3 0 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EMG47647.1 - 1.3e-27 96.1 0.0 3.9e-27 94.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EMG47647.1 - 2.2e-23 82.7 0.0 6.9e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 EMG47647.1 - 1.5e-18 67.2 32.1 1.5e-18 67.2 32.1 4.1 2 1 2 4 4 4 1 Acidic N-terminal SPT6 SH2 PF00017.24 EMG47647.1 - 5.6e-07 29.6 0.0 2.1e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 EMG47647.1 - 8.5e-06 26.6 0.2 0.00014 22.7 0.0 3.2 2 0 0 2 2 2 1 HHH domain DUF2534 PF10749.9 EMG47647.1 - 0.065 13.4 0.2 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) SYF2 PF08231.12 EMG47648.1 - 9.3e-08 32.6 31.2 3.1e-07 30.9 25.5 2.9 1 1 1 2 2 2 1 SYF2 splicing factor DUF1980 PF09323.10 EMG47648.1 - 1.4 8.8 4.6 2.3 8.1 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Methyltransf_3 PF01596.17 EMG47649.1 - 8.7e-17 61.0 0.1 1.2e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EMG47649.1 - 4.5e-09 37.3 0.0 6.4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Syntaxin-18_N PF10496.9 EMG47650.1 - 4.6e-13 49.2 1.1 1.8e-12 47.3 0.5 2.4 1 1 1 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus GTP_EFTU PF00009.27 EMG47651.1 - 5.4e-43 146.8 0.2 1.1e-42 145.9 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EMG47651.1 - 4.6e-14 52.5 8.5 1.4e-13 50.9 8.5 1.8 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 EMG47651.1 - 9.8e-10 38.7 2.7 1.1e-09 38.5 0.1 2.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EMG47651.1 - 2e-06 27.9 0.1 0.039 14.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EMG47651.1 - 0.019 15.2 0.1 0.1 12.9 0.0 2.3 2 1 1 3 3 3 0 AAA domain Roc PF08477.13 EMG47651.1 - 0.039 14.2 0.2 6.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 EMG47651.1 - 0.048 14.1 0.9 0.11 12.8 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EMG47651.1 - 0.057 13.3 0.4 0.26 11.2 0.4 2.1 1 0 0 1 1 1 0 Elongation factor Tu domain 4 DUF2856 PF11043.8 EMG47651.1 - 0.12 12.5 0.7 0.85 9.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2856) SMC_ScpA PF02616.14 EMG47651.1 - 4.9 7.0 7.2 3.3 7.5 4.0 2.0 2 0 0 2 2 2 0 Segregation and condensation protein ScpA MFS_1 PF07690.16 EMG47652.1 - 1.2e-37 129.7 34.0 1.2e-37 129.7 34.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG47652.1 - 4.9e-13 48.7 11.9 4.9e-13 48.7 11.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Pam17 PF08566.10 EMG47652.1 - 0.58 10.0 5.8 4.9 7.0 1.2 2.5 1 1 1 2 2 2 0 Mitochondrial import protein Pam17 DUF2628 PF10947.8 EMG47652.1 - 1.6 9.1 8.7 0.046 14.1 1.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2628) MFS_1 PF07690.16 EMG47653.1 - 2.8e-38 131.8 37.1 2.8e-38 131.8 37.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG47653.1 - 1.1e-13 50.9 9.8 1.1e-13 50.9 9.8 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter eIF3_N PF09440.10 EMG47653.1 - 0.17 12.3 1.0 0.23 11.9 1.0 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain OATP PF03137.20 EMG47653.1 - 4.6 5.4 19.6 0.3 9.3 4.7 3.2 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PMT PF02366.18 EMG47654.1 - 3e-90 302.1 16.9 3e-90 302.1 16.9 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EMG47654.1 - 9.3e-60 201.6 20.7 9.3e-60 201.6 20.7 2.1 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EMG47654.1 - 3e-45 154.4 0.1 3e-45 154.4 0.1 2.0 2 0 0 2 2 2 1 MIR domain PDCD2_C PF04194.13 EMG47655.1 - 2.5e-35 122.1 9.2 1.3e-32 113.3 7.4 3.5 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain UPF1_Zn_bind PF09416.10 EMG47655.1 - 0.021 14.8 0.2 0.044 13.8 0.2 1.5 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) FoP_duplication PF13865.6 EMG47655.1 - 0.36 11.4 8.2 0.38 11.3 0.1 2.6 1 1 1 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 GTP_EFTU PF00009.27 EMG47656.1 - 8.3e-33 113.6 5.4 9.3e-31 106.9 5.4 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EMG47656.1 - 9.2e-28 96.4 0.8 9.2e-28 96.4 0.8 2.6 3 0 0 3 3 3 1 Translation-initiation factor 2 IF2_N PF04760.15 EMG47656.1 - 3.4e-10 39.6 0.0 8.7e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 EMG47656.1 - 1.8e-09 37.7 0.7 5.1e-09 36.2 0.2 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EMG47656.1 - 4.4e-05 23.8 0.4 0.031 14.6 0.0 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Arf PF00025.21 EMG47656.1 - 0.00086 18.8 0.4 0.0024 17.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 EMG47656.1 - 0.011 15.2 2.6 0.014 14.8 0.3 2.4 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 EMG47656.1 - 0.013 15.4 0.8 0.013 15.4 0.8 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Ras PF00071.22 EMG47656.1 - 0.016 14.8 0.2 0.038 13.6 0.2 1.7 1 0 0 1 1 1 0 Ras family FeoB_N PF02421.18 EMG47656.1 - 0.025 14.1 0.0 0.065 12.8 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EMG47656.1 - 0.085 12.9 2.0 14 5.7 0.1 3.4 2 1 1 3 3 3 0 Dynamin family MMR_HSR1_Xtn PF16897.5 EMG47656.1 - 0.091 12.8 1.7 0.16 12.0 0.1 2.3 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain DUF2924 PF11149.8 EMG47656.1 - 2.3 8.6 6.7 9.7 6.6 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2924) Dfp1_Him1_M PF08630.10 EMG47657.1 - 1e-34 119.5 1.1 2.5e-34 118.2 0.0 2.3 3 0 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.12 EMG47657.1 - 2.8e-20 72.1 1.6 8.2e-20 70.7 1.6 1.9 1 0 0 1 1 1 1 DBF zinc finger TPD52 PF04201.15 EMG47657.1 - 0.021 14.4 0.1 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Tumour protein D52 family DUF2052 PF09747.9 EMG47657.1 - 0.96 9.5 9.4 0.24 11.5 5.2 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Plasmodium_Vir PF05795.11 EMG47658.1 - 0.0034 16.9 3.0 0.0037 16.7 3.0 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein DAG_kinase_N PF14513.6 EMG47658.1 - 0.083 13.1 0.9 0.16 12.2 0.9 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus SRP-alpha_N PF04086.13 EMG47658.1 - 0.1 12.5 7.4 0.13 12.2 7.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Tmemb_cc2 PF10267.9 EMG47658.1 - 0.15 11.2 5.0 0.18 10.9 5.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RIFIN PF02009.16 EMG47658.1 - 0.24 11.3 0.7 0.31 10.9 0.7 1.2 1 0 0 1 1 1 0 Rifin Glypican PF01153.19 EMG47658.1 - 0.94 8.2 5.4 1.2 7.9 5.4 1.1 1 0 0 1 1 1 0 Glypican Apt1 PF10351.9 EMG47658.1 - 4.1 6.2 12.5 5 5.9 12.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ApoO PF09769.9 EMG47659.1 - 0.059 13.3 0.6 0.1 12.6 0.6 1.4 1 0 0 1 1 1 0 Apolipoprotein O DUF4321 PF14209.6 EMG47659.1 - 0.45 10.4 2.3 0.79 9.6 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4321) SSP160 PF06933.11 EMG47659.1 - 1.1 7.3 21.3 1.6 6.8 21.3 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Retinal PF15449.6 EMG47660.1 - 3.3 5.4 11.6 4 5.1 11.6 1.0 1 0 0 1 1 1 0 Retinal protein E1-E2_ATPase PF00122.20 EMG47661.1 - 1.6e-32 112.5 26.8 5.2e-29 101.1 0.1 4.3 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMG47661.1 - 8.5e-22 77.7 5.6 8.5e-22 77.7 5.6 3.4 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMG47661.1 - 3.5e-17 63.4 0.1 1.2e-15 58.4 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMG47661.1 - 6.9e-17 61.3 0.0 1.4e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EMG47661.1 - 3e-13 49.2 0.9 4.5e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMG47661.1 - 0.00061 19.6 1.0 0.0028 17.4 1.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Porin_3 PF01459.22 EMG47663.1 - 5.1e-83 278.6 1.1 6.1e-83 278.4 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin MFS_1 PF07690.16 EMG47664.1 - 1.3e-17 63.8 23.2 1.7e-17 63.4 23.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 EMG47664.1 - 0.013 13.5 0.0 0.02 12.9 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4500 PF14937.6 EMG47664.1 - 0.21 11.6 0.9 0.51 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) DUF3302 PF11742.8 EMG47665.1 - 0.097 12.8 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) TRAP_alpha PF03896.16 EMG47666.1 - 0.042 13.1 0.6 0.051 12.8 0.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Calc_CGRP_IAPP PF00214.19 EMG47666.1 - 0.11 12.9 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Astro_capsid_p PF12226.8 EMG47666.1 - 1.2 8.2 5.5 1.4 8.0 5.5 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 EMG47666.1 - 2.3 6.4 6.5 2.7 6.2 6.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 EMG47666.1 - 2.4 6.5 13.0 2.9 6.2 13.0 1.0 1 0 0 1 1 1 0 Mpp10 protein Ribosomal_S24e PF01282.19 EMG47667.1 - 0.0028 17.6 0.5 0.0095 15.9 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S24e SnAPC_2_like PF11035.8 EMG47667.1 - 0.73 9.9 3.0 1.7 8.7 0.3 2.2 2 1 0 2 2 2 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb SH3_1 PF00018.28 EMG47668.1 - 3e-10 39.6 0.1 3e-10 39.6 0.1 2.1 2 1 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EMG47668.1 - 6.7e-09 35.5 0.1 6.7e-09 35.5 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EMG47668.1 - 1.2e-08 34.4 0.1 2.3e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain EP400_N PF15790.5 EMG47668.1 - 2.4 6.9 7.8 4 6.2 7.8 1.3 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal RWD PF05773.22 EMG47669.1 - 2.8e-23 82.4 4.1 5.4e-23 81.5 4.1 1.5 1 0 0 1 1 1 1 RWD domain Rhomboid PF01694.22 EMG47670.1 - 1.3e-10 41.5 12.3 1.9e-10 40.9 12.3 1.1 1 0 0 1 1 1 1 Rhomboid family Med9 PF07544.13 EMG47670.1 - 5.6e-10 39.2 0.4 5.8e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 MethyltransfD12 PF02086.15 EMG47670.1 - 0.031 14.0 0.1 0.046 13.4 0.1 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Phage_Treg PF04761.12 EMG47670.1 - 0.14 12.2 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator Inp1 PF12634.7 EMG47671.1 - 4.2e-15 56.0 0.2 2.5e-14 53.4 0.2 2.4 1 1 0 1 1 1 1 Inheritance of peroxisomes protein 1 MFS_1 PF07690.16 EMG47672.1 - 4.6e-18 65.3 26.3 6.9e-17 61.4 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG47672.1 - 1.2e-16 60.7 15.1 1.9e-16 60.0 15.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF485 PF04341.12 EMG47672.1 - 1.4 8.9 9.7 7.4 6.6 1.5 3.9 3 0 0 3 3 3 0 Protein of unknown function, DUF485 WAK PF08488.11 EMG47673.1 - 0.052 14.1 0.0 0.078 13.5 0.0 1.3 1 0 0 1 1 1 0 Wall-associated kinase Amidase PF01425.21 EMG47673.1 - 0.057 12.4 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Amidase MFS_1 PF07690.16 EMG47674.1 - 1e-21 77.3 22.2 1.4e-21 76.8 22.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EMG47674.1 - 0.00031 19.7 5.5 0.00031 19.7 5.5 1.4 1 1 0 1 1 1 1 MFS_1 like family V_ATPase_I PF01496.19 EMG47674.1 - 0.004 15.2 0.0 0.0071 14.3 0.0 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Aldedh PF00171.22 EMG47675.1 - 2.5e-77 260.4 0.0 3.2e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CD24 PF14984.6 EMG47675.1 - 4.4 7.6 4.9 0.93 9.8 0.2 2.4 2 0 0 2 2 2 0 CD24 protein MFS_1 PF07690.16 EMG47676.1 - 2.9e-19 69.2 23.1 3.8e-19 68.8 23.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 EMG47676.1 - 0.0005 18.1 0.0 0.00085 17.4 0.0 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4500 PF14937.6 EMG47676.1 - 0.054 13.5 1.7 0.42 10.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) MFS_1 PF07690.16 EMG47677.1 - 2.1e-11 43.4 20.3 2.8e-11 43.0 20.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 EMG47677.1 - 0.00091 17.3 0.0 0.0013 16.8 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1077 PF06417.12 EMG47677.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) RTP1_C1 PF10363.9 EMG47678.1 - 2.3e-30 105.1 3.9 1.7e-29 102.3 0.1 4.2 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EMG47678.1 - 1.3e-09 37.5 0.3 3.8e-09 36.1 0.3 1.9 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 IF-2B PF01008.17 EMG47678.1 - 0.017 14.3 0.3 0.03 13.5 0.3 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family RhodobacterPufX PF11511.8 EMG47678.1 - 0.17 11.5 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Ank_2 PF12796.7 EMG47679.1 - 2.3e-12 47.4 0.4 6e-12 46.0 0.2 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMG47679.1 - 2.6e-12 46.7 0.8 9.8e-10 38.5 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMG47679.1 - 1.3e-10 41.6 0.1 2.6e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EMG47679.1 - 5.4e-10 39.3 0.1 4e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EMG47679.1 - 2.1e-09 36.8 0.1 2.5e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat DUF4337 PF14235.6 EMG47679.1 - 0.39 10.8 3.3 0.49 10.5 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) eIF-5_eIF-2B PF01873.17 EMG47680.1 - 1.4e-39 134.6 0.0 2.4e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.15 EMG47680.1 - 0.0087 15.9 0.1 0.067 13.0 0.0 2.4 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region GET2 PF08690.10 EMG47680.1 - 0.079 12.6 3.0 0.11 12.2 3.0 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 zf-HYPF PF07503.12 EMG47680.1 - 0.091 12.5 0.1 18 5.2 0.0 2.4 2 0 0 2 2 2 0 HypF finger TF_Zn_Ribbon PF08271.12 EMG47680.1 - 0.093 12.3 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2752 PF10825.8 EMG47680.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) MBG PF17883.1 EMG47680.1 - 0.15 12.7 1.4 0.23 12.1 1.0 1.5 1 1 0 1 1 1 0 MBG domain Ndc1_Nup PF09531.10 EMG47680.1 - 0.47 9.1 3.7 0.58 8.8 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SIT PF15330.6 EMG47680.1 - 0.54 10.7 3.0 1 9.8 2.6 1.7 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Pkinase PF00069.25 EMG47682.1 - 6.6e-41 140.4 0.1 3.9e-25 88.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMG47682.1 - 4.7e-20 72.0 0.0 4.9e-13 49.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EMG47682.1 - 0.028 13.8 0.0 0.063 12.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 EMG47682.1 - 0.048 13.3 0.1 0.083 12.5 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Aldo_ket_red PF00248.21 EMG47683.1 - 1e-41 143.1 0.0 5.1e-40 137.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GLTT PF01744.20 EMG47683.1 - 0.84 9.5 3.0 0.61 9.9 1.0 1.8 2 0 0 2 2 2 0 GLTT repeat (6 copies) ANAPC4_WD40 PF12894.7 EMG47684.1 - 8.6e-11 42.0 0.0 0.31 11.4 0.0 5.3 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMG47684.1 - 3.6e-08 33.9 0.5 2.1 9.4 0.0 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat Peptidase_S64 PF08192.11 EMG47684.1 - 0.011 14.3 5.8 0.014 13.9 5.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Coiled-coil_56 PF09813.9 EMG47685.1 - 0.0083 16.2 0.0 0.0088 16.1 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 KCH PF16944.5 EMG47686.1 - 4.5e-79 265.8 29.9 5.9e-79 265.4 29.9 1.1 1 0 0 1 1 1 1 Fungal potassium channel PRIMA1 PF16101.5 EMG47686.1 - 3.2 7.8 4.3 1.1 9.4 0.7 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RNase_HII PF01351.18 EMG47687.1 - 3.4e-54 183.7 0.0 4.5e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII 2-oxoacid_dh PF00198.23 EMG47688.1 - 6.3e-74 248.3 0.1 8.1e-74 248.0 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EMG47688.1 - 4.9e-17 61.5 0.1 8.8e-17 60.7 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EMG47688.1 - 1.2e-12 47.9 0.2 2.8e-12 46.7 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain His_Phos_1 PF00300.22 EMG47689.1 - 1.1e-17 64.3 0.0 2e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.9 EMG47689.1 - 2.8e-10 39.9 0.2 8.1e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 TFIIIC subunit triple barrel domain Sec23_trunk PF04811.15 EMG47690.1 - 3.7e-49 167.5 0.6 3.3e-48 164.4 0.6 2.1 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EMG47690.1 - 2.1e-29 102.1 0.0 1.7e-28 99.2 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EMG47690.1 - 7.6e-26 89.9 0.2 2.7e-25 88.2 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EMG47690.1 - 2e-10 40.5 6.4 4e-10 39.6 6.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EMG47690.1 - 7e-10 38.7 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-RRN7 PF11781.8 EMG47690.1 - 0.24 11.1 2.8 0.3 10.8 1.0 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn_clus PF00172.18 EMG47691.1 - 2.5e-08 33.9 10.5 5.3e-08 32.9 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMG47691.1 - 0.0008 18.5 0.1 0.0008 18.5 0.1 3.2 3 1 1 4 4 4 2 Fungal specific transcription factor domain DUF4355 PF14265.6 EMG47691.1 - 0.006 16.8 0.8 0.006 16.8 0.8 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4355) MPM1 PF17234.2 EMG47691.1 - 4.7 7.4 17.6 5.1 7.3 5.3 2.6 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 GNAT_acetyltr_2 PF13718.6 EMG47691.1 - 5.5 6.3 8.5 0.55 9.6 1.2 2.4 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DMAP1_like PF17024.5 EMG47692.1 - 0.034 14.3 2.1 0.17 12.0 0.1 2.3 2 0 0 2 2 2 0 Putative DMAP1-like Pyridox_oxase_2 PF12766.7 EMG47693.1 - 4e-29 101.2 0.1 8e-29 100.2 0.1 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EMG47693.1 - 1.6e-07 31.4 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Thioredoxin PF00085.20 EMG47694.1 - 4.6e-55 184.0 0.1 5.3e-28 97.0 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EMG47694.1 - 5.5e-25 88.3 9.1 9.6e-20 71.3 3.9 4.6 3 1 1 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EMG47694.1 - 2.9e-09 36.7 0.0 0.00063 19.2 0.0 2.8 2 1 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EMG47694.1 - 1.1e-08 35.5 4.9 0.0011 19.4 0.0 3.2 4 0 0 4 4 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EMG47694.1 - 4e-06 26.9 0.0 0.011 15.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EMG47694.1 - 1.4e-05 25.3 1.9 0.79 10.1 0.1 5.1 4 2 2 6 6 6 2 Thioredoxin-like AhpC-TSA PF00578.21 EMG47694.1 - 0.00022 21.1 0.3 0.22 11.5 0.0 3.4 2 1 1 3 3 3 1 AhpC/TSA family Redoxin PF08534.10 EMG47694.1 - 0.019 14.7 0.1 0.65 9.7 0.0 2.7 3 0 0 3 3 3 0 Redoxin CDC45 PF02724.14 EMG47694.1 - 0.19 10.0 4.7 0.25 9.6 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 EMG47694.1 - 0.21 11.8 11.0 0.39 11.0 11.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Glutaredoxin PF00462.24 EMG47694.1 - 4.6 7.5 5.5 33 4.8 0.1 3.3 3 1 0 3 3 3 0 Glutaredoxin WD40 PF00400.32 EMG47695.1 - 1.3e-16 60.7 7.3 3.6e-05 24.4 0.0 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG47695.1 - 0.00014 22.1 0.1 0.12 12.7 0.0 3.7 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpc4 PF05132.14 EMG47695.1 - 0.2 12.1 0.8 0.33 11.4 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 La PF05383.17 EMG47696.1 - 1.2e-16 60.5 0.3 2.4e-16 59.5 0.3 1.6 1 0 0 1 1 1 1 La domain Tim17 PF02466.19 EMG47697.1 - 6.3e-06 26.5 0.1 2.2e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family T2SSF PF00482.23 EMG47697.1 - 0.045 13.7 0.0 9 6.3 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF2963 PF11178.8 EMG47697.1 - 0.31 10.8 2.4 0.55 10.0 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) Hyr1 PF15789.5 EMG47698.1 - 3.7e-12 45.6 59.7 0.00069 19.1 8.7 6.9 5 1 0 5 5 5 4 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG47698.1 - 0.11 12.9 25.0 1.1 9.8 0.9 5.5 3 2 1 5 5 5 0 Family of unknown function (DUF5628) Lin-8 PF03353.15 EMG47698.1 - 5.3 6.5 9.7 8.8 5.8 9.7 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2415 PF10313.9 EMG47699.1 - 1.2e-20 73.1 0.5 3e-20 71.9 0.5 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Hyr1 PF15789.5 EMG47702.1 - 3.6e-05 23.2 5.9 3.6e-05 23.2 5.9 2.9 3 0 0 3 3 3 1 Hyphally regulated cell wall GPI-anchored protein 1 VasI PF11319.8 EMG47702.1 - 0.11 12.1 1.8 0.098 12.3 0.6 1.5 1 1 1 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 Hexapep PF00132.24 EMG47703.1 - 0.13 12.0 1.1 0.47 10.3 0.2 2.4 2 1 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) DUF963 PF06131.11 EMG47703.1 - 0.3 10.5 25.5 0.19 11.2 0.7 5.0 4 2 1 5 5 5 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Hyr1 PF15789.5 EMG47704.1 - 6.5e-17 60.8 35.8 1.2e-09 37.6 7.4 4.4 4 0 0 4 4 4 3 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG47704.1 - 4e-05 24.0 1.9 0.091 13.2 0.2 2.9 2 0 0 2 2 2 2 Family of unknown function (DUF5628) Chitin_bind_4 PF00379.23 EMG47704.1 - 0.0012 19.3 2.0 1.1 9.8 0.1 3.2 2 0 0 2 2 2 2 Insect cuticle protein Hyphal_reg_CWP PF11765.8 EMG47705.1 - 2.2e-132 441.0 12.9 2.5e-132 440.8 12.9 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 EMG47707.1 - 0.00014 21.3 7.6 0.00014 21.3 7.6 2.9 2 0 0 2 2 2 1 Hyphally regulated cell wall GPI-anchored protein 1 Hyr1 PF15789.5 EMG47708.1 - 3.2e-25 87.4 57.5 5.4e-11 41.9 8.6 5.4 4 1 0 4 4 4 4 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG47708.1 - 0.0075 16.7 17.7 0.098 13.1 0.2 4.3 3 2 2 5 5 5 3 Family of unknown function (DUF5628) Pput2613-deam PF14427.6 EMG47708.1 - 0.0092 15.9 1.8 0.81 9.6 0.1 3.2 2 1 0 3 3 3 1 Pput_2613-like deaminase Chitin_bind_4 PF00379.23 EMG47708.1 - 0.38 11.3 7.9 11 6.6 0.4 3.8 3 0 0 3 3 3 0 Insect cuticle protein Hyphal_reg_CWP PF11765.8 EMG47709.1 - 1e-131 438.8 9.1 1.2e-131 438.6 9.1 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal LRR_8 PF13855.6 EMG47712.1 - 4e-45 151.4 80.1 6.5e-09 35.4 8.3 10.7 5 3 7 12 12 12 11 Leucine rich repeat PP2C PF00481.21 EMG47712.1 - 1.1e-44 153.0 0.0 1.1e-44 153.0 0.0 2.5 3 0 0 3 3 3 1 Protein phosphatase 2C LRR_4 PF12799.7 EMG47712.1 - 6.9e-31 105.8 105.3 6.9e-05 23.1 5.6 13.9 6 3 7 16 16 16 13 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EMG47712.1 - 5.7e-27 94.5 0.0 1.3e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 EMG47712.1 - 6.9e-07 28.9 30.4 2.5e-05 23.8 2.0 5.4 3 2 2 5 5 5 2 Leucine-rich repeat LRR_5 PF13306.6 EMG47712.1 - 9e-05 22.4 19.8 0.047 13.6 6.0 4.8 3 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) PP2C_2 PF13672.6 EMG47712.1 - 0.025 14.2 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C RsmF_methylt_CI PF17126.5 EMG47712.1 - 0.11 12.6 1.5 7.9 6.6 0.0 4.3 4 2 2 6 6 6 0 RsmF rRNA methyltransferase first C-terminal domain LRR_1 PF00560.33 EMG47712.1 - 0.13 12.9 85.0 1.4 9.7 0.2 18.1 18 1 0 18 18 18 0 Leucine Rich Repeat SAPS PF04499.15 EMG47713.1 - 2.8e-191 636.6 8.4 2.8e-191 636.6 8.4 3.2 3 0 0 3 3 3 2 SIT4 phosphatase-associated protein GATase_4 PF13230.6 EMG47714.1 - 1.1e-12 47.5 0.0 2.1e-12 46.5 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EMG47714.1 - 3.8e-11 43.3 0.0 6.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF1687 PF07955.11 EMG47715.1 - 1.1e-37 129.3 1.1 1.6e-37 128.9 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Rap1a PF18602.1 EMG47715.1 - 0.16 12.3 0.1 0.56 10.6 0.0 1.9 2 0 0 2 2 2 0 Rap1a immunity proteins ChAPs PF09295.10 EMG47716.1 - 2.2e-28 99.4 1.9 3.6e-24 85.5 0.2 2.7 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) Septin PF00735.18 EMG47717.1 - 5.6e-80 268.6 4.1 5.6e-80 268.6 4.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EMG47717.1 - 3.3e-07 30.4 0.0 1e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMG47717.1 - 3.1e-05 23.9 3.8 4.3e-05 23.5 0.1 2.5 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 EMG47717.1 - 0.00027 21.5 0.5 0.0015 19.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 EMG47717.1 - 0.0015 18.8 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EMG47717.1 - 0.0021 17.6 1.3 0.12 11.9 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EMG47717.1 - 0.0029 17.0 0.0 0.0029 17.0 0.0 1.8 2 0 0 2 2 2 1 AIG1 family AAA_29 PF13555.6 EMG47717.1 - 0.008 15.9 0.2 0.017 14.8 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.18 EMG47717.1 - 0.047 13.2 0.1 0.18 11.4 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 EMG47717.1 - 0.078 13.3 0.1 0.29 11.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMG47717.1 - 0.12 11.9 0.3 2.4 7.6 0.1 2.5 2 1 1 3 3 3 0 P-loop containing dynein motor region AAA_16 PF13191.6 EMG47717.1 - 0.14 12.5 0.1 0.33 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Coatomer_E PF04733.14 EMG47718.1 - 1.8e-08 34.2 0.6 0.00016 21.2 0.1 2.2 2 0 0 2 2 2 2 Coatomer epsilon subunit TPR_MalT PF17874.1 EMG47718.1 - 0.065 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 MalT-like TPR region cNMP_binding PF00027.29 EMG47719.1 - 7.6e-34 115.6 0.0 4.6e-21 74.7 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ribosomal_L1 PF00687.21 EMG47720.1 - 4.2e-22 78.9 1.3 6e-22 78.4 1.3 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Gaa1 PF04114.14 EMG47721.1 - 7.2e-110 368.3 15.8 6.1e-105 352.1 1.3 2.1 2 0 0 2 2 2 2 Gaa1-like, GPI transamidase component ANAPC4 PF12896.7 EMG47722.1 - 2.2e-46 157.9 4.9 3.8e-46 157.2 4.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EMG47722.1 - 2.7e-11 43.6 0.0 6.9e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PCI PF01399.27 EMG47722.1 - 0.51 10.9 6.3 5.1 7.7 0.9 3.4 4 0 0 4 4 4 0 PCI domain Hyphal_reg_CWP PF11765.8 EMG47723.1 - 1.7e-89 300.1 13.3 1.9e-89 299.9 13.3 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Beta_protein PF14350.6 EMG47723.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Beta protein ABC_tran PF00005.27 EMG47724.1 - 3.3e-09 37.4 0.0 3.7e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMG47724.1 - 0.048 13.1 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Cofilin_ADF PF00241.20 EMG47725.1 - 1e-37 128.6 1.7 1.1e-37 128.4 1.7 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3341 PF11821.8 EMG47727.1 - 0.49 10.0 4.7 0.71 9.5 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3341) CT_A_B PF02626.15 EMG47729.1 - 5.1e-68 229.5 0.0 5.6e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CT_C_D PF02682.16 EMG47730.1 - 5.6e-21 75.2 0.0 6.9e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D CT_C_D PF02682.16 EMG47731.1 - 3.6e-14 53.0 0.3 4.7e-14 52.6 0.3 1.2 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Hat1_N PF10394.9 EMG47732.1 - 3.5e-45 154.1 2.6 3.5e-45 154.1 2.6 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EMG47732.1 - 2.1e-05 24.7 0.0 3.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 EMG47732.1 - 0.013 15.2 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 MOZ/SAS family IES5 PF17335.2 EMG47732.1 - 0.027 14.7 0.3 0.061 13.6 0.3 1.5 1 0 0 1 1 1 0 Ino80 complex subunit 5 Rad21_Rec8 PF04824.16 EMG47733.1 - 0.0039 16.4 0.1 0.0072 15.6 0.1 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Pil1 PF13805.6 EMG47734.1 - 2.5e-123 410.8 0.3 3e-123 410.5 0.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.10 EMG47734.1 - 0.0057 16.8 1.1 0.07 13.4 0.4 2.5 2 0 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit Nop10p PF04135.12 EMG47734.1 - 0.28 11.2 3.8 3.9 7.6 0.2 2.4 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family HMGL-like PF00682.19 EMG47735.1 - 9.6e-57 192.5 0.2 1.5e-56 191.9 0.2 1.3 1 0 0 1 1 1 1 HMGL-like FtsX_ECD PF18075.1 EMG47735.1 - 0.071 13.7 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsX extracellular domain FliG_N PF14842.6 EMG47735.1 - 0.17 12.4 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain Rsa3 PF14615.6 EMG47736.1 - 5e-19 67.6 1.4 1.1e-18 66.5 1.4 1.6 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Prominin PF05478.11 EMG47736.1 - 0.092 10.7 5.6 0.1 10.5 5.6 1.1 1 0 0 1 1 1 0 Prominin Hph PF13694.6 EMG47736.1 - 0.23 11.7 18.9 2.8 8.2 18.9 2.0 1 1 0 1 1 1 0 Sec63/Sec62 complex-interacting family O-antigen_lig PF13425.6 EMG47736.1 - 8.2 5.1 7.2 11 4.7 7.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SPATA3 PF15662.5 EMG47736.1 - 9.2 6.8 11.5 13 6.4 11.5 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family PA PF02225.22 EMG47737.1 - 2.3e-09 37.2 0.0 4.8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 PA domain TFR_dimer PF04253.15 EMG47737.1 - 0.03 14.4 0.1 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Hyphal_reg_CWP PF11765.8 EMG47738.1 - 2.6e-57 194.2 10.9 3.1e-57 194.0 10.9 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Aldo_ket_red PF00248.21 EMG47739.1 - 3.4e-65 220.1 0.0 4e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hyphal_reg_CWP PF11765.8 EMG47740.1 - 2.8e-77 259.9 13.8 3.6e-77 259.5 13.8 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Arm_APC_u3 PF16629.5 EMG47740.1 - 0.0089 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Armadillo-associated region on APC RPM2 PF08579.11 EMG47741.1 - 1e-29 103.3 15.0 8e-29 100.5 1.9 4.5 2 1 2 4 4 4 2 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.6 EMG47741.1 - 0.0038 17.4 6.3 0.19 12.0 0.1 4.9 4 1 0 4 4 4 2 PPR repeat family PPR PF01535.20 EMG47741.1 - 1.3 9.5 2.9 12 6.5 0.1 4.0 4 0 0 4 4 4 0 PPR repeat TCO89 PF10452.9 EMG47742.1 - 4.3e-10 39.2 54.8 5.2e-07 29.0 0.6 3.8 2 1 0 3 3 3 3 TORC1 subunit TCO89 DUF4407 PF14362.6 EMG47742.1 - 0.038 13.4 5.1 0.08 12.3 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4309 PF14172.6 EMG47742.1 - 0.39 10.7 2.8 6.6 6.7 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4309) Metallophos PF00149.28 EMG47743.1 - 2.5e-11 44.4 7.3 2.5e-11 44.4 7.3 3.6 3 1 0 3 3 3 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 EMG47744.1 - 9.5e-07 29.5 6.6 9.5e-07 29.5 6.6 3.0 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase RRM_1 PF00076.22 EMG47745.1 - 7.1e-13 48.2 0.0 1.1e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 EMG47746.1 - 7.7e-22 77.9 0.2 7.7e-22 77.9 0.2 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG47746.1 - 1.5e-09 37.5 0.0 2.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG47746.1 - 0.00074 18.9 0.5 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like ParcG PF10274.9 EMG47746.1 - 0.013 15.6 6.4 0.021 15.0 0.9 3.3 2 1 1 3 3 3 0 Parkin co-regulated protein EF-G-binding_N PF07299.11 EMG47746.1 - 0.42 11.2 8.1 1.2 9.7 0.8 3.5 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal FA_hydroxylase PF04116.13 EMG47747.1 - 1.5e-22 80.4 21.4 1.9e-22 80.1 16.8 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily EXS PF03124.14 EMG47748.1 - 2.1e-97 326.4 31.7 3.1e-97 325.9 31.7 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EMG47748.1 - 1e-60 206.7 23.1 1e-60 206.7 23.1 2.3 2 0 0 2 2 2 1 SPX domain CENP-B_dimeris PF09026.10 EMG47748.1 - 2.5 8.6 7.3 4.8 7.6 3.5 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain ADH_N PF08240.12 EMG47749.1 - 7.9e-30 103.0 1.3 1.7e-29 101.9 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMG47749.1 - 2e-14 53.7 0.0 3.5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMG47749.1 - 2.5e-06 27.2 0.1 4.7e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus DZR PF12773.7 EMG47749.1 - 0.035 14.1 0.2 0.19 11.8 0.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon Methyltransf_11 PF08241.12 EMG47752.1 - 2.5e-14 53.7 0.0 4.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG47752.1 - 4.3e-13 49.8 0.0 7.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG47752.1 - 9.6e-10 39.1 0.0 2.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMG47752.1 - 4.2e-09 36.1 0.0 6.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EMG47752.1 - 1.3e-06 28.4 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EMG47752.1 - 0.00013 21.1 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 EMG47752.1 - 0.0029 17.4 0.1 0.038 13.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMG47752.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Mannosyl_trans3 PF11051.8 EMG47753.1 - 4.2e-79 265.8 0.3 4.2e-79 265.8 0.3 2.1 2 0 0 2 2 2 1 Mannosyltransferase putative YchF-GTPase_C PF06071.13 EMG47754.1 - 4.4e-35 119.7 0.9 1.1e-34 118.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EMG47754.1 - 7e-16 58.3 0.0 1.9e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EMG47754.1 - 0.0022 18.0 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EMG47754.1 - 0.015 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF3236 PF11576.8 EMG47754.1 - 0.19 11.4 0.7 0.35 10.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Asp PF00026.23 EMG47755.1 - 4.6e-61 207.0 9.6 6.7e-42 144.0 5.2 2.5 3 0 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMG47755.1 - 3.5e-14 53.4 0.6 3.5e-14 53.4 0.6 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMG47755.1 - 0.044 14.4 8.1 22 5.8 0.0 4.5 5 0 0 5 5 5 0 Aspartyl protease gag-asp_proteas PF13975.6 EMG47755.1 - 0.11 13.1 1.5 73 4.0 0.0 4.3 4 1 0 4 4 4 0 gag-polyprotein putative aspartyl protease DIL PF01843.19 EMG47756.1 - 1e-20 73.9 4.8 5.8e-20 71.5 3.4 2.9 2 1 0 2 2 2 1 DIL domain Ank_2 PF12796.7 EMG47756.1 - 2.3e-12 47.3 0.1 7.1e-12 45.7 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMG47756.1 - 4.2e-09 35.9 3.7 0.0027 18.1 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EMG47756.1 - 9.1e-09 35.4 4.5 0.0023 18.3 0.4 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EMG47756.1 - 4e-08 33.4 0.9 0.0087 16.4 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMG47756.1 - 8.9e-06 26.2 3.2 0.00031 21.3 0.7 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EMG47756.1 - 2.3 8.2 8.3 0.31 11.0 0.9 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3447) CIMR PF00878.18 EMG47757.1 - 5.6e-11 42.7 2.0 8.1e-05 22.7 0.1 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EMG47757.1 - 1.6e-07 30.7 1.1 2.1e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EMG47757.1 - 0.0006 19.8 0.6 0.0006 19.8 0.6 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 SLM4 PF16818.5 EMG47757.1 - 0.014 15.3 0.4 0.035 14.1 0.3 1.8 2 0 0 2 2 2 0 Protein SLM4 Pro_Al_protease PF02983.14 EMG47757.1 - 0.26 11.4 1.2 0.34 11.0 0.1 1.7 2 0 0 2 2 2 0 Alpha-lytic protease prodomain PRKCSH PF07915.13 EMG47757.1 - 1.4 10.0 6.4 0.25 12.4 2.0 2.0 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Adaptin_N PF01602.20 EMG47758.1 - 1.4e-96 324.1 13.9 1.9e-96 323.8 13.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EMG47758.1 - 1.1e-44 152.2 1.9 1.1e-44 152.2 1.9 1.8 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EMG47758.1 - 3.6e-29 101.2 0.0 8.2e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EMG47758.1 - 1.3e-14 54.3 0.1 2.1e-07 31.2 0.0 4.8 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EMG47758.1 - 5.9e-09 36.2 17.9 1.1e-05 25.5 0.2 5.6 3 1 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EMG47758.1 - 0.00043 20.3 3.2 5 7.7 0.1 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 EMG47758.1 - 0.0014 19.1 1.1 0.62 10.6 0.2 3.6 3 0 0 3 3 3 1 HEAT-like repeat PAC3 PF10178.9 EMG47758.1 - 0.016 15.3 0.1 0.064 13.4 0.1 2.0 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 Sld5 PF05916.11 EMG47759.1 - 4.3e-21 75.4 0.5 6.8e-21 74.8 0.5 1.3 1 0 0 1 1 1 1 GINS complex protein NAT PF04768.13 EMG47760.1 - 4.4e-44 150.1 0.9 6.5e-44 149.6 0.1 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase HlyIII PF03006.20 EMG47761.1 - 3.3e-46 157.8 16.8 3.7e-46 157.6 16.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF3589 PF12141.8 EMG47762.1 - 8.6e-187 621.6 1.4 1e-186 621.4 1.4 1.0 1 0 0 1 1 1 1 Beta-mannosyltransferases Cation_efflux PF01545.21 EMG47763.1 - 5.2e-43 147.1 12.4 7.9e-43 146.5 12.4 1.3 1 0 0 1 1 1 1 Cation efflux family KAsynt_C_assoc PF16197.5 EMG47763.1 - 2.4 8.6 5.0 0.24 11.9 0.2 1.9 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension CLU PF13236.6 EMG47764.1 - 1.1e-71 241.2 0.0 2.7e-71 239.9 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EMG47764.1 - 4e-53 180.0 0.1 4e-53 180.0 0.1 2.2 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 EMG47764.1 - 6.5e-21 74.5 0.4 3.2e-20 72.3 0.4 2.4 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 EMG47764.1 - 7.3e-18 64.6 7.4 3.9e-10 39.9 0.1 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EMG47764.1 - 7.4e-11 41.6 0.0 0.21 11.5 0.0 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EMG47764.1 - 0.0079 15.6 1.0 0.014 14.8 0.0 1.8 2 1 0 2 2 2 1 MalT-like TPR region Menin PF05053.13 EMG47764.1 - 0.086 11.2 14.2 0.045 12.1 2.6 2.3 2 0 0 2 2 2 0 Menin SPO22 PF08631.10 EMG47764.1 - 0.21 11.1 4.2 9.2 5.7 0.3 3.1 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like DUF5308 PF17233.2 EMG47764.1 - 3.4 7.9 8.3 0.75 10.0 0.3 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5308) F-box-like PF12937.7 EMG47765.1 - 7.7e-11 41.7 0.1 1.5e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMG47765.1 - 3.9e-09 36.2 0.1 8.7e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EMG47765.1 - 0.0011 19.2 0.0 0.31 11.4 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMG47765.1 - 0.076 13.9 3.1 2.6 9.1 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat F-box_4 PF15966.5 EMG47765.1 - 0.076 12.9 0.2 0.25 11.3 0.0 1.9 1 1 0 2 2 2 0 F-box UIM PF02809.20 EMG47765.1 - 0.22 11.5 3.8 1.4 9.1 0.1 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Tub_N PF16322.5 EMG47765.1 - 0.33 11.3 6.7 0.64 10.4 6.7 1.4 1 0 0 1 1 1 0 Tubby N-terminal Phosphodiest PF01663.22 EMG47766.1 - 2e-12 47.4 0.6 3.3e-11 43.4 0.6 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EMG47766.1 - 0.0085 15.5 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily zf-C2H2_2 PF12756.7 EMG47767.1 - 6.4e-30 103.5 2.2 1.7e-29 102.1 2.2 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EMG47767.1 - 0.38 11.1 1.6 0.97 9.8 1.6 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DNA_pol_A_exo1 PF01612.20 EMG47768.1 - 1.8e-46 158.0 0.7 5e-46 156.6 0.2 2.0 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.12 EMG47768.1 - 8e-17 61.7 0.7 8e-17 61.7 0.7 2.8 2 1 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EMG47768.1 - 1.7e-07 31.1 0.1 5.3e-07 29.5 0.1 1.9 1 0 0 1 1 1 1 HRDC domain IL12 PF03039.14 EMG47768.1 - 0.13 11.6 0.7 0.33 10.3 0.1 2.0 2 0 0 2 2 2 0 Interleukin-12 alpha subunit Syntaxin_2 PF14523.6 EMG47768.1 - 0.96 9.9 4.0 0.79 10.1 0.2 2.7 3 0 0 3 3 3 0 Syntaxin-like protein CLN3 PF02487.17 EMG47769.1 - 4.9e-144 480.3 25.7 6.5e-142 473.3 25.7 2.0 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EMG47769.1 - 2.7e-06 26.6 2.7 2.7e-06 26.6 2.7 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DAHP_synth_1 PF00793.20 EMG47770.1 - 3.8e-107 357.3 0.0 4.5e-107 357.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-CCCH PF00642.24 EMG47772.1 - 9.1e-11 41.4 10.1 1.3e-05 25.0 1.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EMG47772.1 - 1.2e-08 34.8 12.1 6.6e-05 22.8 3.0 2.3 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EMG47772.1 - 1.5e-06 28.8 4.1 0.011 16.4 0.1 3.1 3 0 0 3 3 3 2 Torus domain RRM_1 PF00076.22 EMG47772.1 - 0.00015 21.5 0.0 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 EMG47772.1 - 0.0029 17.4 11.1 0.012 15.4 3.2 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EMG47772.1 - 0.023 14.9 0.3 5.9 7.1 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 EMG47772.1 - 2.3 8.8 8.3 5.6 7.6 2.0 2.6 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger AA_permease_2 PF13520.6 EMG47773.1 - 2.9e-52 177.9 40.0 3.6e-52 177.6 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG47773.1 - 3.2e-24 85.4 32.3 4.1e-24 85.0 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease Sigma_M_inh PF17453.2 EMG47773.1 - 4.3 7.9 8.4 14 6.2 0.2 3.8 4 0 0 4 4 4 0 Sigma-M inhibitor Hydrolase_like PF13242.6 EMG47775.1 - 5.3e-23 80.9 0.2 5.9e-22 77.5 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EMG47775.1 - 2.3e-19 69.4 0.0 6.5e-19 67.9 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMG47775.1 - 0.01 16.1 0.0 3.5 7.8 0.0 3.0 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase GATA PF00320.27 EMG47776.1 - 5.4e-15 54.7 4.1 1.1e-14 53.8 4.1 1.5 1 0 0 1 1 1 1 GATA zinc finger CUE PF02845.16 EMG47778.1 - 3.8e-12 45.6 0.0 7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 CUE domain NDUF_B7 PF05676.13 EMG47779.1 - 6.1e-19 67.5 5.2 6.9e-19 67.3 5.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PTN_MK_C PF01091.18 EMG47779.1 - 0.023 15.1 0.2 0.023 15.1 0.2 1.6 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain Trefoil PF00088.18 EMG47779.1 - 0.056 13.3 2.3 2.2 8.2 0.2 2.8 1 1 1 2 2 2 0 Trefoil (P-type) domain Hydin_ADK PF17213.3 EMG47781.1 - 1.7 8.8 4.5 1 9.6 2.3 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain RRM_1 PF00076.22 EMG47782.1 - 1.6e-20 72.7 0.1 2.1e-20 72.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMG47782.1 - 0.0048 17.0 0.1 0.019 15.1 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif SdiA-regulated PF06977.11 EMG47782.1 - 0.098 11.9 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 SdiA-regulated TMEM223 PF14640.6 EMG47783.1 - 0.00096 19.4 0.0 0.0036 17.5 0.0 2.0 1 1 0 1 1 1 1 Transmembrane protein 223 DUF898 PF05987.13 EMG47783.1 - 0.041 12.9 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) FtsX PF02687.21 EMG47783.1 - 0.16 12.5 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsX-like permease family Trs65 PF12735.7 EMG47784.1 - 7.7e-75 252.2 2.9 7.7e-75 252.2 2.9 1.5 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 F-box-like PF12937.7 EMG47785.1 - 5.7e-05 22.9 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like DUF1461 PF07314.11 EMG47785.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DUF5591 PF17884.1 EMG47785.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) LRR_4 PF12799.7 EMG47785.1 - 0.18 12.3 11.5 19 5.8 0.0 5.8 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) DUF72 PF01904.18 EMG47785.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF72 Peptidase_M3 PF01432.20 EMG47786.1 - 5.3e-145 484.2 1.2 9.9e-145 483.3 1.2 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EMG47786.1 - 0.18 11.5 0.1 0.29 10.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like HGTP_anticodon PF03129.20 EMG47787.1 - 1e-23 83.3 0.1 2.6e-23 82.0 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EMG47787.1 - 1.1e-07 32.0 0.0 3.4e-07 30.4 0.0 1.9 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) ABA_GPCR PF12430.8 EMG47788.1 - 1.5e-54 184.5 5.9 1.5e-54 184.5 5.9 2.3 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EMG47788.1 - 1.6e-20 72.9 1.1 6.3e-20 71.0 0.0 2.6 3 0 0 3 3 3 1 The Golgi pH Regulator (GPHR) Family N-terminal Mhr1 PF12829.7 EMG47789.1 - 2.7e-23 81.9 0.8 4.6e-23 81.1 0.8 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Polbeta PF18765.1 EMG47789.1 - 0.084 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase FAD_binding_2 PF00890.24 EMG47790.1 - 4.8e-123 411.3 3.0 6.1e-123 411.0 3.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EMG47790.1 - 4.2e-44 149.6 0.7 6.2e-44 149.1 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 EMG47790.1 - 3.3e-06 26.5 0.2 0.0026 17.0 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EMG47790.1 - 5.7e-06 25.7 0.4 0.0023 17.1 1.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EMG47790.1 - 1.3e-05 24.7 0.3 0.00013 21.3 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMG47790.1 - 0.0017 18.0 1.3 0.015 14.9 1.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMG47790.1 - 0.0068 15.7 0.1 0.017 14.4 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMG47790.1 - 0.012 14.4 0.1 0.26 10.0 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FKBP_N_2 PF18023.1 EMG47790.1 - 0.061 13.4 0.3 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 BDBT FKBP like N-terminal AAA PF00004.29 EMG47791.1 - 2.8e-40 137.8 0.0 4.7e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMG47791.1 - 4.2e-05 23.6 0.0 0.00017 21.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMG47791.1 - 6e-05 23.3 0.0 0.0024 18.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EMG47791.1 - 0.00015 22.2 0.1 0.0032 17.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EMG47791.1 - 0.00027 21.1 0.0 0.00063 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EMG47791.1 - 0.00046 19.4 0.0 0.00075 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EMG47791.1 - 0.0038 17.0 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EMG47791.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMG47791.1 - 0.016 14.7 0.0 0.041 13.4 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EMG47791.1 - 0.019 15.2 0.0 0.046 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 EMG47791.1 - 0.03 14.7 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EMG47791.1 - 0.033 14.7 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EMG47791.1 - 0.034 14.1 0.0 4.6 7.1 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EMG47791.1 - 0.035 13.8 0.1 0.074 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EMG47791.1 - 0.037 13.4 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EMG47791.1 - 0.04 13.1 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 EMG47791.1 - 0.04 13.8 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EMG47791.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EMG47791.1 - 0.13 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EMG47791.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EMG47791.1 - 0.2 11.8 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_pol_Rbc25 PF08292.12 EMG47792.1 - 1.9e-41 141.3 0.9 2.6e-41 140.9 0.9 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EMG47792.1 - 4.1e-14 52.7 0.0 6.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RT_RNaseH PF17917.1 EMG47793.1 - 3.2e-25 88.4 0.0 1.2e-24 86.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EMG47793.1 - 8.7e-23 80.3 0.0 2.2e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 EMG47793.1 - 2.2e-16 59.7 1.4 5.8e-16 58.3 0.3 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 EMG47793.1 - 8.8e-13 48.5 0.0 2.3e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 EMG47793.1 - 1.2e-09 38.1 0.3 3.2e-09 36.6 0.2 1.8 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 EMG47793.1 - 0.0043 17.2 0.1 0.021 15.0 0.1 2.3 2 0 0 2 2 2 1 H2C2 zinc finger Retrotrans_gag PF03732.17 EMG47793.1 - 0.42 10.9 2.1 1.5 9.2 0.0 3.0 2 1 1 3 3 3 0 Retrotransposon gag protein Spt20 PF12090.8 EMG47794.1 - 7.6e-53 179.5 9.8 7.6e-53 179.5 9.8 8.6 3 2 4 7 7 7 1 Spt20 family SecY PF00344.20 EMG47795.1 - 5.3e-42 144.1 16.7 7.1e-42 143.7 16.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EMG47795.1 - 2.6e-11 43.2 1.3 2.6e-11 43.2 1.3 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p DMRL_synthase PF00885.19 EMG47797.1 - 8.5e-54 181.2 0.0 9.5e-54 181.1 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase FHA PF00498.26 EMG47798.1 - 8.1e-08 32.5 0.5 2.8e-07 30.8 0.4 2.1 1 1 1 2 2 2 1 FHA domain PBP1_TM PF14812.6 EMG47798.1 - 0.58 10.6 0.0 0.58 10.6 0.0 6.3 6 1 0 6 6 6 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Raptor_N PF14538.6 EMG47799.1 - 5.5e-65 217.8 0.1 1.5e-64 216.4 0.1 1.8 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EMG47799.1 - 5.3e-08 33.4 5.5 0.62 11.0 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat Cnd1 PF12717.7 EMG47799.1 - 0.009 16.1 0.0 0.2 11.7 0.0 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 EMG47799.1 - 0.075 13.3 0.3 12 6.2 0.2 3.6 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT PF02985.22 EMG47799.1 - 0.095 13.0 0.0 24 5.5 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat Mito_carr PF00153.27 EMG47800.1 - 5.3e-64 212.2 0.7 2.5e-25 88.2 0.3 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein PsaL PF02605.15 EMG47800.1 - 0.0018 18.0 0.2 0.0037 16.9 0.2 1.5 1 0 0 1 1 1 1 Photosystem I reaction centre subunit XI Serine_protease PF18405.1 EMG47800.1 - 0.032 13.4 0.0 0.082 12.1 0.0 1.7 1 0 0 1 1 1 0 Gammaproteobacterial serine protease ApoO PF09769.9 EMG47802.1 - 1.9e-38 131.3 1.2 6.5e-37 126.4 0.1 2.8 3 0 0 3 3 3 1 Apolipoprotein O Rsm22 PF09243.10 EMG47803.1 - 2.3e-26 92.7 0.3 7.1e-08 32.1 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 EMG47803.1 - 7.7e-05 22.6 0.0 0.00036 20.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG47803.1 - 0.065 14.0 0.0 0.31 11.8 0.0 2.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S27e PF01667.17 EMG47804.1 - 5.7e-26 90.0 2.6 7.4e-26 89.6 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 Mu-like_Com PF10122.9 EMG47804.1 - 0.057 12.9 2.8 0.46 10.0 0.1 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com DUF1980 PF09323.10 EMG47805.1 - 0.021 14.8 0.0 0.021 14.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Pkinase PF00069.25 EMG47806.1 - 9.4e-27 94.0 0.0 4.8e-26 91.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG47806.1 - 3e-15 56.2 0.0 1.1e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG47806.1 - 8.7e-05 21.5 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase zf-ribbon_3 PF13248.6 EMG47806.1 - 0.14 11.6 0.9 0.3 10.6 0.3 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Rif1_N PF12231.8 EMG47807.1 - 3.3e-35 121.8 11.6 1.1e-34 120.1 11.6 1.8 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal efThoc1 PF11957.8 EMG47808.1 - 7.4e-20 71.1 28.3 7.4e-20 71.1 28.3 3.3 2 1 1 3 3 3 1 THO complex subunit 1 transcription elongation factor RF-1 PF00472.20 EMG47808.1 - 3.2e-18 65.7 0.2 3.2e-18 65.7 0.2 3.3 3 1 0 3 3 3 1 RF-1 domain Redoxin PF08534.10 EMG47809.1 - 1.9e-32 112.0 0.1 2.3e-32 111.7 0.1 1.0 1 0 0 1 1 1 1 Redoxin DCP1 PF06058.13 EMG47810.1 - 7.1e-27 93.7 0.0 1.1e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family DUF3395 PF11875.8 EMG47810.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Zn_clus PF00172.18 EMG47811.1 - 1.3e-08 34.8 11.6 1.3e-08 34.8 11.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.9 EMG47811.1 - 0.053 13.6 2.1 0.11 12.6 2.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) SLX9 PF15341.6 EMG47811.1 - 0.082 13.3 0.4 0.2 12.0 0.4 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Ras PF00071.22 EMG47812.1 - 4.7e-42 143.3 0.6 5.7e-42 143.1 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG47812.1 - 8.9e-34 116.3 0.1 1.5e-33 115.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG47812.1 - 3.7e-14 52.6 0.1 5.1e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMG47812.1 - 1e-07 31.6 0.7 1.4e-07 31.1 0.7 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMG47812.1 - 1.6e-05 25.0 0.1 2.9e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EMG47812.1 - 1.9e-05 24.2 0.1 5.2e-05 22.7 0.1 1.5 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EMG47812.1 - 0.0011 18.9 0.7 0.49 10.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EMG47812.1 - 0.0017 18.1 0.3 0.67 9.7 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EMG47812.1 - 0.02 15.3 0.0 0.031 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EMG47812.1 - 0.051 13.0 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 EMG47812.1 - 0.054 13.2 0.1 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EMG47812.1 - 0.077 13.0 0.6 0.17 12.0 0.5 1.8 1 1 0 1 1 1 0 Dynamin family AAA_7 PF12775.7 EMG47812.1 - 0.082 12.4 0.9 0.2 11.1 0.1 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region NTP_transf_2 PF01909.23 EMG47813.1 - 4.1e-16 59.0 0.0 4.1e-16 59.0 0.0 2.7 2 1 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EMG47813.1 - 9.4e-13 48.2 1.0 1.6e-12 47.4 0.1 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 EMG47813.1 - 0.00034 20.6 2.8 0.0023 18.0 0.0 2.6 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Glucan_synthase PF02364.15 EMG47815.1 - 0 1165.7 2.7 0 1165.2 2.7 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EMG47815.1 - 9.2e-36 123.0 5.9 1.5e-17 64.2 0.2 2.7 1 1 1 2 2 2 2 1,3-beta-glucan synthase subunit FKS1, domain-1 SSB PF00436.25 EMG47816.1 - 2.1e-19 69.5 0.4 2.6e-19 69.2 0.4 1.1 1 0 0 1 1 1 1 Single-strand binding protein family RMI1_N PF08585.12 EMG47816.1 - 0.015 15.0 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 RecQ mediated genome instability protein tRNA_anti-codon PF01336.25 EMG47816.1 - 0.027 14.4 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Peptidase_M28 PF04389.17 EMG47817.1 - 6.7e-25 87.9 0.0 1.1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EMG47817.1 - 0.0064 16.2 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nucleoporin_N PF08801.11 EMG47818.1 - 4.6e-136 454.0 15.4 8e-136 453.2 15.4 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EMG47818.1 - 6e-109 365.4 12.2 2e-108 363.7 12.2 1.8 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal HMW1C_N PF18071.1 EMG47818.1 - 0.015 15.1 1.6 4.1 7.2 0.2 2.9 2 0 0 2 2 2 0 HMW1C N-terminal PRK PF00485.18 EMG47819.1 - 4.6e-15 55.9 0.0 5.4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family DEAD PF00270.29 EMG47820.1 - 1.2e-44 152.2 1.4 2.2e-44 151.3 1.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG47820.1 - 7.1e-32 110.0 0.8 9e-31 106.5 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG47820.1 - 1e-05 25.6 0.1 2.2e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMG47820.1 - 0.00051 19.8 0.4 0.0014 18.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EMG47820.1 - 0.00079 19.8 0.2 0.0015 18.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain UvsW PF11637.8 EMG47820.1 - 0.00095 19.2 0.8 0.0045 17.1 0.1 2.6 3 0 0 3 3 3 1 ATP-dependant DNA helicase UvsW Helicase_RecD PF05127.14 EMG47820.1 - 0.0032 17.3 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF4767 PF15983.5 EMG47820.1 - 0.011 16.0 0.2 0.23 11.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4767) AAA PF00004.29 EMG47820.1 - 0.025 15.0 0.7 0.1 13.0 0.7 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMG47820.1 - 0.049 13.9 0.1 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 EMG47820.1 - 0.15 12.0 0.5 0.57 10.1 0.1 2.3 2 1 0 2 2 2 0 Flavivirus DEAD domain HEAT_EZ PF13513.6 EMG47821.1 - 1.1e-17 64.1 2.8 5.3e-10 39.6 0.0 7.3 9 0 0 9 9 7 2 HEAT-like repeat HEAT PF02985.22 EMG47821.1 - 1.6e-10 40.3 2.2 0.036 14.3 0.0 7.8 10 0 0 10 10 7 3 HEAT repeat RIX1 PF08167.12 EMG47821.1 - 4.6e-10 39.5 0.2 0.0019 17.9 0.0 5.2 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 EMG47821.1 - 8.1e-07 29.3 0.3 0.23 11.9 0.0 6.0 5 1 2 7 7 6 1 HEAT repeats Cnd1 PF12717.7 EMG47821.1 - 3.5e-06 27.1 2.2 1.5 8.9 0.1 6.0 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EMG47821.1 - 1.2e-05 25.8 4.8 8.7 7.0 0.1 6.5 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EMG47821.1 - 6.9e-05 23.0 2.0 0.93 9.7 0.1 4.7 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 EMG47821.1 - 0.00021 21.3 1.6 0.22 11.4 0.0 5.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) ParcG PF10274.9 EMG47821.1 - 0.00044 20.4 0.6 3 7.9 0.3 3.8 2 2 1 3 3 3 1 Parkin co-regulated protein UME PF08064.13 EMG47821.1 - 0.0023 17.8 1.5 41 4.2 0.0 6.5 4 2 3 7 7 6 0 UME (NUC010) domain CLASP_N PF12348.8 EMG47821.1 - 0.004 16.7 1.2 0.49 9.9 0.0 4.3 5 1 0 5 5 5 1 CLASP N terminal TetR_C_27 PF17935.1 EMG47821.1 - 0.062 13.4 0.2 23 5.1 0.0 3.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NUC173 PF08161.12 EMG47821.1 - 0.071 12.8 0.3 18 4.9 0.0 3.6 4 0 0 4 4 3 0 NUC173 domain PAD_M PF08527.10 EMG47821.1 - 0.076 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain RICTOR_V PF14668.6 EMG47821.1 - 0.078 13.2 0.8 8.1 6.8 0.0 4.2 3 1 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 MMS19_C PF12460.8 EMG47821.1 - 0.2 10.7 17.6 0.023 13.8 0.8 4.4 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal Tti2 PF10521.9 EMG47821.1 - 0.4 10.2 4.3 7.4 6.0 0.0 4.5 3 2 3 6 6 6 0 Tti2 family STE3 PF02076.15 EMG47822.1 - 3.5e-81 272.6 25.4 4.3e-81 272.3 25.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor Orf78 PF06024.12 EMG47822.1 - 0.22 11.8 6.5 8.1 6.8 2.5 2.8 2 0 0 2 2 2 0 Orf78 (ac78) GatB_N PF02934.15 EMG47823.1 - 2.8e-92 309.0 0.0 3.8e-92 308.5 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EMG47823.1 - 9e-27 93.8 0.3 1.4e-26 93.1 0.3 1.3 1 0 0 1 1 1 1 GatB domain SIL1 PF16782.5 EMG47823.1 - 0.046 12.9 0.1 0.11 11.7 0.1 1.7 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 NPL4 PF05021.15 EMG47824.1 - 1.9e-135 451.1 0.1 2.7e-135 450.6 0.1 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EMG47824.1 - 1.7e-61 206.6 0.3 4.3e-61 205.3 0.1 1.7 2 0 0 2 2 2 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EMG47824.1 - 2.6e-06 27.8 0.1 6.8e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 HSP70 PF00012.20 EMG47826.1 - 1.6e-167 558.3 6.1 1.6e-167 558.3 6.1 2.1 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EMG47826.1 - 9.2e-12 44.4 0.0 2.3e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein HsbA PF12296.8 EMG47826.1 - 0.032 14.7 0.0 0.087 13.3 0.0 1.7 1 0 0 1 1 1 0 Hydrophobic surface binding protein A NLE PF08154.12 EMG47826.1 - 0.053 14.0 0.4 0.26 11.9 0.1 2.3 2 0 0 2 2 2 0 NLE (NUC135) domain Pkinase PF00069.25 EMG47827.1 - 3.3e-47 161.1 4.1 3.4e-24 85.6 2.2 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMG47827.1 - 1.3e-17 64.0 1.4 2.1e-13 50.2 0.5 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Anth_Ig PF05587.13 EMG47827.1 - 0.12 12.7 0.9 0.3 11.4 0.9 1.6 1 0 0 1 1 1 0 Anthrax receptor extracellular domain FTA2 PF13095.6 EMG47827.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.2 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 P34-Arc PF04045.14 EMG47828.1 - 2.7e-102 341.6 2.0 3.3e-102 341.3 2.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Ribosom_S12_S23 PF00164.25 EMG47829.1 - 4e-35 119.9 2.2 5.5e-35 119.4 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF1833 PF08875.11 EMG47829.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) PP-binding PF00550.25 EMG47830.1 - 1.5e-12 47.6 0.4 2.1e-12 47.2 0.4 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EMG47830.1 - 9.8e-05 22.5 0.2 0.00014 22.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-carrier Focal_AT PF03623.13 EMG47830.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Focal adhesion targeting region QCR10 PF09796.9 EMG47831.1 - 1.3e-22 79.6 0.8 1.5e-22 79.4 0.8 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.10 EMG47831.1 - 0.01 15.7 0.3 0.015 15.2 0.2 1.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Cullin PF00888.22 EMG47832.1 - 1.8e-59 201.9 30.3 1.8e-59 201.9 30.3 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EMG47832.1 - 1.8e-13 50.3 3.5 8.2e-13 48.2 3.5 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain FrhB_FdhB_C PF04432.13 EMG47832.1 - 0.018 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Rrf2 PF02082.20 EMG47832.1 - 0.092 13.1 0.0 0.66 10.4 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator ACP_PD PF04336.12 EMG47832.1 - 2.9 8.4 5.6 0.54 10.7 0.1 2.7 4 0 0 4 4 4 0 Acyl carrier protein phosphodiesterase DUF2796 PF10986.8 EMG47833.1 - 0.017 15.1 14.5 0.023 14.7 14.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DUF5376 PF17346.2 EMG47833.1 - 0.027 14.8 2.1 0.048 14.0 2.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5376) SelP_N PF04592.14 EMG47833.1 - 0.076 12.4 17.7 0.098 12.1 17.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 EMG47833.1 - 0.41 9.2 14.4 0.47 8.9 14.4 1.1 1 0 0 1 1 1 0 Macoilin family Androgen_recep PF02166.16 EMG47833.1 - 0.71 8.6 6.0 0.86 8.4 6.0 1.2 1 0 0 1 1 1 0 Androgen receptor ApbA PF02558.16 EMG47834.1 - 4.1e-26 91.4 0.0 5.8e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EMG47834.1 - 7.9e-24 84.2 0.0 1.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.27 EMG47834.1 - 0.01 16.4 0.1 0.022 15.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMG47834.1 - 0.039 13.5 0.3 0.085 12.4 0.2 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EMG47834.1 - 0.15 12.5 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EMG47834.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Phos_pyr_kin PF08543.12 EMG47835.1 - 9.2e-13 48.1 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EMG47835.1 - 7.2e-06 25.5 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Hemolysin_N PF12563.8 EMG47835.1 - 0.046 13.3 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Hemolytic toxin N terminal bZIP_2 PF07716.15 EMG47836.1 - 2.9e-05 24.0 11.3 2.9e-05 24.0 11.3 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EMG47836.1 - 0.00014 21.9 9.8 0.00014 21.9 9.8 1.9 1 1 0 1 1 1 1 bZIP transcription factor Gag_p17 PF00540.18 EMG47836.1 - 0.019 15.0 1.2 0.019 15.0 1.2 2.0 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) DUF3926 PF13080.6 EMG47836.1 - 0.028 14.4 0.2 0.15 12.0 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Cyto_heme_lyase PF01265.17 EMG47836.1 - 0.67 9.5 16.9 0.022 14.4 8.1 2.2 2 0 0 2 2 2 0 Cytochrome c/c1 heme lyase CLZ PF16526.5 EMG47836.1 - 4.6 7.7 9.7 0.5 10.8 0.6 3.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pirin PF02678.16 EMG47837.1 - 1.3e-26 92.6 0.0 2.4e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EMG47837.1 - 4.6e-15 55.9 0.2 1.1e-14 54.7 0.2 1.6 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EMG47837.1 - 0.036 13.8 0.1 0.09 12.5 0.1 1.6 1 0 0 1 1 1 0 Cupin domain ABC_trans_N PF14510.6 EMG47839.1 - 3.8e-11 43.4 1.7 5.7e-11 42.9 0.1 2.3 2 1 0 2 2 2 1 ABC-transporter N-terminal ABC_tran PF00005.27 EMG47839.1 - 5e-05 23.8 1.2 0.00012 22.6 0.0 2.2 2 1 0 2 2 2 1 ABC transporter Pirin PF02678.16 EMG47840.1 - 4.9e-26 90.8 0.1 6.8e-26 90.4 0.1 1.2 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EMG47840.1 - 0.00064 19.4 0.2 0.0011 18.7 0.2 1.4 1 0 0 1 1 1 1 Cupin domain zf-C3HC4_3 PF13920.6 EMG47841.1 - 0.46 10.4 8.8 0.95 9.4 5.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0370 PF13980.6 EMG47841.1 - 1.1 9.3 5.0 21 5.2 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) DUF4603 PF15376.6 EMG47842.1 - 0.012 13.0 0.2 0.015 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF3446 PF11928.8 EMG47842.1 - 3.1 8.2 12.2 0.098 13.0 5.2 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain Peptidase_M20 PF01546.28 EMG47843.1 - 1.5e-24 86.9 0.0 1.6e-23 83.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMG47843.1 - 3.1e-10 39.9 0.0 9.9e-10 38.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain WD40 PF00400.32 EMG47843.1 - 4.8e-10 39.9 9.5 0.04 14.8 0.2 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG47843.1 - 5.7e-06 26.5 0.3 0.015 15.6 0.0 4.2 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M28 PF04389.17 EMG47843.1 - 8.3e-05 22.4 0.0 0.0091 15.7 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M28 HPS3_N PF14761.6 EMG47843.1 - 0.0032 17.0 1.4 0.43 10.1 0.2 3.6 2 1 2 4 4 4 1 Hermansky-Pudlak syndrome 3 Frtz PF11768.8 EMG47843.1 - 0.053 11.8 0.6 0.3 9.3 0.2 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF620 PF04788.12 EMG47843.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF620) SPX PF03105.19 EMG47844.1 - 1e-55 190.3 18.5 1.2e-55 190.0 18.5 1.1 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.19 EMG47844.1 - 1.4e-26 93.6 44.6 1.9e-26 93.2 44.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EMG47844.1 - 6.8e-21 74.8 63.1 1e-17 64.3 33.3 2.3 2 1 1 3 3 3 2 Citrate transporter ASFV_J13L PF05568.11 EMG47844.1 - 0.11 12.3 0.7 1.4 8.7 0.3 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein IRF PF00605.17 EMG47844.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor SRP54_N PF02881.19 EMG47845.1 - 0.13 12.5 0.3 0.59 10.4 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Pirin PF02678.16 EMG47847.1 - 7.9e-24 83.7 0.0 1.7e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EMG47847.1 - 3.4e-17 62.7 0.1 6.2e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Pirin PF02678.16 EMG47848.1 - 2.3e-28 98.3 0.0 4.4e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EMG47848.1 - 7.5e-18 64.8 0.1 1.6e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EMG47848.1 - 0.02 14.6 0.1 0.051 13.3 0.1 1.6 1 0 0 1 1 1 0 Cupin domain Erf4 PF10256.9 EMG47849.1 - 0.21 11.7 1.3 2.9 8.0 0.1 2.5 1 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Pirin PF02678.16 EMG47851.1 - 2.1e-27 95.2 0.3 3.8e-27 94.4 0.3 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EMG47851.1 - 3.2e-16 59.6 0.1 3.9e-15 56.1 0.1 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EMG47851.1 - 0.00023 20.8 3.4 0.0027 17.4 0.3 2.3 2 0 0 2 2 2 2 Cupin domain Peptidase_S10 PF00450.22 EMG47853.1 - 4.1e-128 428.4 0.1 5.8e-128 427.9 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase COX14 PF14880.6 EMG47855.1 - 1e-13 50.9 0.0 1.2e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Rtf2 PF04641.12 EMG47856.1 - 3.5e-31 108.5 5.9 5.9e-31 107.8 5.9 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-UDP PF14569.6 EMG47856.1 - 0.13 12.4 2.3 0.25 11.5 2.3 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Rad10 PF03834.14 EMG47857.1 - 1.3e-38 131.5 0.2 2e-38 130.9 0.2 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Methyltransf_11 PF08241.12 EMG47858.1 - 1.4e-18 67.3 0.0 3.1e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG47858.1 - 1.2e-16 61.1 0.0 2.4e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG47858.1 - 4.3e-10 40.2 0.0 8.5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMG47858.1 - 1.7e-08 34.4 0.0 3.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMG47858.1 - 8.6e-07 28.9 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMG47858.1 - 0.00022 20.7 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EMG47858.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMG47858.1 - 0.0012 18.4 0.0 0.003 17.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EMG47858.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.12 EMG47858.1 - 0.0076 15.8 0.1 0.018 14.5 0.0 1.5 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase DREV PF05219.12 EMG47858.1 - 0.01 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase NodS PF05401.11 EMG47858.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 EMG47858.1 - 0.14 12.0 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Pirin PF02678.16 EMG47859.1 - 2.2e-28 98.4 0.0 4.1e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EMG47859.1 - 4.6e-19 68.7 0.1 9.6e-19 67.7 0.1 1.6 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EMG47859.1 - 0.002 17.8 0.6 0.024 14.3 0.2 2.3 2 0 0 2 2 2 1 Cupin domain Atg8 PF02991.16 EMG47860.1 - 1.3e-47 160.2 0.1 1.7e-47 159.8 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EMG47860.1 - 4.4e-07 30.2 0.0 6.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Tantalus PF15386.6 EMG47860.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 Drosophila Tantalus-like AA_permease_2 PF13520.6 EMG47861.1 - 1.9e-52 178.6 56.4 2.2e-52 178.3 56.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG47861.1 - 6.2e-08 31.7 51.9 8.4e-08 31.2 51.9 1.1 1 0 0 1 1 1 1 Amino acid permease HTH_Bact PF18768.1 EMG47861.1 - 0.16 11.6 0.4 3.3 7.4 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix bacterial domain SusF_SusE PF16411.5 EMG47861.1 - 0.16 12.5 0.6 0.41 11.2 0.0 1.8 2 1 0 2 2 2 0 Outer membrane protein SusF_SusE Ribosomal_L30_N PF08079.12 EMG47862.1 - 7.8e-22 77.3 21.1 1.3e-21 76.6 21.1 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EMG47862.1 - 2.7e-18 65.6 1.6 6.9e-18 64.3 1.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF4407 PF14362.6 EMG47863.1 - 0.00043 19.7 2.4 0.00066 19.1 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF4504 PF14953.6 EMG47863.1 - 0.0014 18.1 4.3 0.0014 18.1 3.2 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4504) DivIC PF04977.15 EMG47863.1 - 0.0038 17.0 1.6 0.0038 17.0 1.6 3.7 2 1 1 4 4 4 1 Septum formation initiator KLRAQ PF10205.9 EMG47863.1 - 0.0043 17.3 12.9 0.0043 17.3 12.9 2.7 2 1 1 3 3 3 1 Predicted coiled-coil domain-containing protein DUF5414 PF17435.2 EMG47863.1 - 0.0052 16.5 2.5 0.012 15.3 0.6 2.2 2 1 0 2 2 2 1 Family of unknown function (DUF5414) CCDC24 PF15669.5 EMG47863.1 - 0.0052 16.7 5.7 0.01 15.7 5.7 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family ERM PF00769.19 EMG47863.1 - 0.03 14.1 15.4 0.044 13.6 15.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Sec34 PF04136.15 EMG47863.1 - 0.15 11.9 14.4 0.067 13.1 3.1 2.6 1 1 1 2 2 2 0 Sec34-like family COG5 PF10392.9 EMG47863.1 - 0.18 12.0 14.3 0.55 10.4 3.6 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Fez1 PF06818.15 EMG47863.1 - 0.23 11.9 20.6 3.2 8.2 20.9 2.1 1 1 0 1 1 1 0 Fez1 BRE1 PF08647.11 EMG47863.1 - 0.32 11.1 22.2 0.1 12.7 3.6 3.2 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF99 PF01949.16 EMG47863.1 - 0.75 9.2 2.9 0.61 9.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF99 YjcZ PF13990.6 EMG47863.1 - 1.8 7.9 6.5 9.2 5.6 2.7 2.1 1 1 1 2 2 2 0 YjcZ-like protein ATG16 PF08614.11 EMG47863.1 - 2.6 8.2 22.5 1.3 9.2 3.7 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Occludin_ELL PF07303.13 EMG47863.1 - 2.9 8.7 14.8 90 3.9 8.9 3.4 2 1 0 2 2 2 0 Occludin homology domain YabA PF06156.13 EMG47863.1 - 3.1 8.5 13.9 1.9e+02 2.7 13.7 2.6 1 1 0 1 1 1 0 Initiation control protein YabA NES_C_h PF18208.1 EMG47863.1 - 3.2 8.1 15.2 0.91 9.8 0.1 3.0 2 1 1 3 3 3 0 Nicking enzyme C-terminal middle helical domain TMF_DNA_bd PF12329.8 EMG47863.1 - 6 6.9 30.7 1e+02 3.0 14.1 3.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding PLU-1 PF08429.11 EMG47864.1 - 1.9e-54 185.1 19.0 4.5e-53 180.6 8.8 2.8 2 1 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EMG47864.1 - 1.1e-20 74.1 0.8 3.3e-10 40.4 0.1 3.1 2 0 0 2 2 2 2 JmjC domain, hydroxylase ARID PF01388.21 EMG47864.1 - 1.2e-17 64.4 0.0 6.3e-17 62.0 0.0 2.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 EMG47864.1 - 8.2e-08 32.0 10.2 1.9e-07 30.9 10.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EMG47864.1 - 0.0015 18.7 0.3 0.0046 17.2 0.3 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EMG47864.1 - 0.016 15.4 0.9 0.047 13.8 0.9 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_1 PF00130.22 EMG47864.1 - 0.039 13.8 2.6 0.076 12.9 2.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ATR13 PF16829.5 EMG47864.1 - 0.048 14.0 0.5 0.25 11.7 0.1 2.4 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector JmjN PF02375.17 EMG47864.1 - 0.049 13.6 1.2 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 jmjN domain zf-RING_2 PF13639.6 EMG47864.1 - 0.35 11.2 8.0 0.73 10.2 8.0 1.5 1 0 0 1 1 1 0 Ring finger domain PHD_4 PF16866.5 EMG47864.1 - 2.1 8.5 8.8 1.8 8.7 6.5 2.1 2 0 0 2 2 2 0 PHD-finger Flocculin_t3 PF13928.6 EMG47865.1 - 5.6e-06 26.8 22.0 0.0023 18.4 3.4 2.4 2 0 0 2 2 2 2 Flocculin type 3 repeat IDO PF01231.18 EMG47866.1 - 2.6e-151 504.3 0.0 3e-151 504.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase HemX PF04375.14 EMG47866.1 - 0.034 13.4 0.1 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase tRNA-synt_His PF13393.6 EMG47867.1 - 8.8e-38 130.3 0.1 7.1e-31 107.6 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EMG47867.1 - 2.5e-11 43.6 0.0 6.1e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EMG47867.1 - 0.00036 20.1 0.0 0.00074 19.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 EMG47867.1 - 0.0021 17.2 0.0 0.059 12.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EMG47867.1 - 0.0028 17.7 1.1 0.053 13.5 0.6 2.8 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) ESCRT-II PF05871.12 EMG47867.1 - 0.22 11.8 0.1 0.4 10.9 0.1 1.4 1 0 0 1 1 1 0 ESCRT-II complex subunit FA_desaturase PF00487.24 EMG47868.1 - 4.4e-26 92.2 10.6 6.7e-26 91.6 10.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EMG47868.1 - 9.4e-18 63.4 0.5 1.9e-17 62.5 0.5 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) EST1_DNA_bind PF10373.9 EMG47869.1 - 5.4e-43 147.5 5.7 1.3e-42 146.2 5.7 1.7 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EMG47869.1 - 3.6e-19 69.7 0.4 3.6e-19 69.7 0.4 2.3 2 1 0 2 2 2 1 Telomerase activating protein Est1 Peptidase_C97 PF05903.14 EMG47870.1 - 2.6e-32 111.7 2.5 3e-32 111.5 1.2 1.7 2 0 0 2 2 2 1 PPPDE putative peptidase domain Wtap PF17098.5 EMG47870.1 - 2.6e-06 27.4 12.0 4.2e-06 26.8 12.0 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family LRAT PF04970.13 EMG47870.1 - 0.055 13.8 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 Lecithin retinol acyltransferase PH PF00169.29 EMG47871.1 - 3.7e-06 27.4 1.7 3.7e-06 27.4 1.7 3.2 3 0 0 3 3 3 1 PH domain DUF3461 PF11944.8 EMG47871.1 - 1.2 9.3 6.5 3.6 7.7 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3461) ILVD_EDD PF00920.21 EMG47872.1 - 9.8e-211 700.8 0.0 1.1e-210 700.7 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Adap_comp_sub PF00928.21 EMG47873.1 - 2e-88 296.2 0.5 2.9e-88 295.7 0.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMG47873.1 - 1.5e-09 37.9 1.6 2.9e-09 37.0 1.6 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Flocculin_t3 PF13928.6 EMG47874.1 - 0.032 14.8 19.9 0.032 14.8 19.9 5.7 2 2 2 4 4 4 0 Flocculin type 3 repeat tRNA_anti-like PF12869.7 EMG47874.1 - 0.21 11.2 2.5 0.55 9.8 0.5 2.4 2 1 1 3 3 3 0 tRNA_anti-like Cellulase PF00150.18 EMG47875.1 - 1.9e-16 60.3 0.5 2e-08 34.0 0.2 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EMG47875.1 - 3e-09 37.3 0.0 7.1e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain HA2 PF04408.23 EMG47876.1 - 1.8e-24 86.1 1.5 1.3e-23 83.4 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EMG47876.1 - 2.6e-19 69.4 0.0 5.8e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EMG47876.1 - 7.4e-13 48.8 0.0 2.2e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EMG47876.1 - 1.3e-10 41.5 0.0 3.4e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EMG47876.1 - 6.6e-07 29.3 0.2 1.5e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMG47876.1 - 0.00036 20.8 0.1 0.0019 18.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMG47876.1 - 0.0013 19.2 8.0 0.062 13.8 0.2 3.9 2 2 0 2 2 2 1 ABC transporter AAA_19 PF13245.6 EMG47876.1 - 0.0017 18.7 0.2 0.0033 17.8 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMG47876.1 - 0.0047 16.7 0.1 0.0085 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMG47876.1 - 0.0056 16.7 0.7 0.099 12.7 0.3 2.8 2 1 0 2 2 1 1 AAA domain DUF2075 PF09848.9 EMG47876.1 - 0.021 14.1 2.9 0.034 13.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EMG47876.1 - 0.023 14.0 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 EMG47876.1 - 0.025 14.1 0.2 0.07 12.6 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Microtub_bd PF16796.5 EMG47876.1 - 0.027 14.4 0.2 11 5.9 0.1 2.6 2 0 0 2 2 2 0 Microtubule binding SRP54 PF00448.22 EMG47876.1 - 0.03 13.9 0.3 0.078 12.6 0.3 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 EMG47876.1 - 0.034 13.6 0.1 0.097 12.1 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 EMG47876.1 - 0.047 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EMG47876.1 - 0.053 13.5 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 EMG47876.1 - 0.069 13.1 1.7 2.2 8.3 0.1 3.0 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 EMG47876.1 - 0.079 13.0 0.1 0.28 11.3 0.1 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 EMG47876.1 - 1.1 9.1 4.3 5.5 6.8 0.1 3.5 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea RPN5_C PF18098.1 EMG47877.1 - 1.9e-16 59.8 0.4 9.9e-16 57.6 0.4 2.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain PCI PF01399.27 EMG47877.1 - 2.3e-15 57.0 2.3 2.3e-15 57.0 2.3 2.5 3 0 0 3 3 3 1 PCI domain VF530 PF09905.9 EMG47877.1 - 0.07 13.3 0.2 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 DNA-binding protein VF530 Suf PF05843.14 EMG47877.1 - 0.36 10.8 5.6 0.18 11.8 1.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Glyco_hydro_72 PF03198.14 EMG47878.1 - 3.7e-135 450.2 4.7 4.6e-135 449.9 4.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase PFK PF00365.20 EMG47879.1 - 4.5e-185 613.5 0.8 6.4e-103 344.0 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 EMG47879.1 - 6e-19 68.3 0.0 1.4e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast TgMIC1 PF11476.8 EMG47879.1 - 0.09 12.5 0.4 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 SPRY PF00622.28 EMG47880.1 - 4.3e-07 30.1 0.0 1.3e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 SPRY domain SMC_Nse1 PF07574.13 EMG47881.1 - 1.4e-17 64.2 0.4 8.1e-16 58.5 0.4 2.0 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EMG47881.1 - 0.0017 18.6 0.2 0.003 17.8 0.2 1.4 1 0 0 1 1 1 1 RING-like domain FlaG PF03646.15 EMG47881.1 - 0.1 12.8 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 FlaG protein PHD PF00628.29 EMG47881.1 - 0.21 11.5 1.1 7.4 6.6 0.1 2.3 2 0 0 2 2 2 0 PHD-finger Glyco_hydro_16 PF00722.21 EMG47882.1 - 6.7e-41 139.7 0.0 1.5e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nop14 PF04147.12 EMG47882.1 - 2.6 6.1 9.1 3.7 5.7 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family R3H-assoc PF13902.6 EMG47882.1 - 3.8 7.9 7.2 8.1 6.8 7.2 1.5 1 1 0 1 1 1 0 R3H-associated N-terminal domain Sugar_tr PF00083.24 EMG47883.1 - 2.6e-64 217.8 14.1 2.9e-64 217.6 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG47883.1 - 0.0011 18.0 10.6 0.0011 18.0 10.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BON PF04972.17 EMG47883.1 - 0.21 11.9 0.0 0.6 10.4 0.0 1.8 2 0 0 2 2 2 0 BON domain Bax1-I PF01027.20 EMG47883.1 - 4.2 7.1 16.8 17 5.1 12.2 2.9 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Alpha-amylase PF00128.24 EMG47884.1 - 9.9e-120 400.1 2.8 9.9e-120 400.1 2.8 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EMG47884.1 - 6.8e-05 22.1 1.3 0.00025 20.3 0.0 2.2 3 0 0 3 3 3 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 EMG47884.1 - 0.00047 20.2 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Sugar_tr PF00083.24 EMG47885.1 - 1e-83 281.7 24.4 1.3e-83 281.4 24.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG47885.1 - 8.3e-19 67.7 23.6 6.4e-18 64.8 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.26 EMG47886.1 - 4.4e-29 101.1 1.2 8.1e-29 100.2 1.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG47886.1 - 6.7e-29 100.0 0.4 1.2e-28 99.2 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMG47886.1 - 2.9e-06 28.4 0.0 4.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMG47886.1 - 0.012 15.1 0.5 0.018 14.5 0.5 1.3 1 0 0 1 1 1 0 short chain dehydrogenase F-box-like PF12937.7 EMG47888.1 - 0.032 14.1 0.3 0.1 12.5 0.3 1.9 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 EMG47888.1 - 1.8 9.1 7.3 8.2 7.0 0.1 4.8 3 2 0 4 4 4 0 Leucine Rich repeats (2 copies) Alpha-amylase PF00128.24 EMG47889.1 - 1.4e-119 399.6 1.7 1.4e-119 399.6 1.7 1.9 2 1 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EMG47889.1 - 4.5e-05 22.7 0.1 0.00015 21.0 0.0 1.8 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 EMG47889.1 - 0.0034 17.5 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Sugar_tr PF00083.24 EMG47890.1 - 7.5e-07 28.4 0.7 7.5e-07 28.4 0.7 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter DUF5301 PF17225.3 EMG47890.1 - 0.038 14.4 0.4 0.057 13.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) DUF915 PF06028.11 EMG47890.1 - 0.075 12.4 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MFS_1 PF07690.16 EMG47890.1 - 0.098 11.6 3.5 0.16 10.8 3.5 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily Sin3a_C PF16879.5 EMG47890.1 - 0.14 11.8 0.2 0.19 11.4 0.2 1.1 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein Glyco_transf_22 PF03901.17 EMG47891.1 - 7e-06 25.5 0.0 8.9e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Nucleos_tra2_N PF01773.20 EMG47891.1 - 0.051 14.2 0.0 0.074 13.7 0.0 1.3 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus Peptidase_C2 PF00648.21 EMG47892.1 - 3.1e-13 49.4 0.0 6.8e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EMG47892.1 - 0.0024 18.1 4.0 0.47 10.7 1.3 3.6 2 1 0 2 2 2 2 Calpain large subunit, domain III OST3_OST6 PF04756.13 EMG47893.1 - 3.7e-98 328.5 4.8 4.4e-98 328.3 4.8 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family ORMDL PF04061.14 EMG47893.1 - 0.019 14.8 4.1 0.043 13.6 4.1 1.5 1 0 0 1 1 1 0 ORMDL family RNA_pol_Rpb1_6 PF04992.14 EMG47893.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 6 Thioredoxin PF00085.20 EMG47893.1 - 0.12 12.3 0.0 1.5 8.9 0.0 2.3 1 1 0 1 1 1 0 Thioredoxin DUF676 PF05057.14 EMG47894.1 - 2.4e-52 177.6 0.0 4.1e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 EMG47894.1 - 0.00079 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 EMG47894.1 - 0.00098 19.0 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EMG47894.1 - 0.0027 17.5 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein RNA_pol_Rpb4 PF03874.16 EMG47895.1 - 7.1e-29 100.6 1.2 9.4e-29 100.2 1.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 FmiP_Thoc5 PF09766.9 EMG47895.1 - 0.0089 15.4 0.2 0.015 14.6 0.2 1.4 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Fungal_trans PF04082.18 EMG47897.1 - 9.7e-33 113.3 12.6 4.1e-32 111.3 8.9 3.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG47897.1 - 4.5e-10 39.5 10.5 1e-09 38.4 10.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KH_1 PF00013.29 EMG47900.1 - 0.0031 17.3 0.5 16 5.5 0.0 4.3 4 1 0 4 4 4 3 KH domain ATG16 PF08614.11 EMG47901.1 - 4.4e-10 40.1 21.4 8.2e-10 39.2 21.4 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Tetrabrachion PF11401.8 EMG47901.1 - 0.025 14.6 2.8 0.03 14.3 0.7 2.2 2 0 0 2 2 2 0 Tetrabrachion FAM76 PF16046.5 EMG47901.1 - 0.093 12.1 13.9 0.12 11.7 13.9 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4446 PF14584.6 EMG47901.1 - 0.22 11.5 7.8 0.27 11.2 5.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) EF-hand_1 PF00036.32 EMG47902.1 - 3.5e-29 98.1 18.2 1.1e-07 30.9 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EMG47902.1 - 1.8e-23 82.7 7.4 1.3e-12 48.0 0.8 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EMG47902.1 - 2.6e-23 79.9 11.7 1.3e-05 24.8 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EMG47902.1 - 5.2e-20 70.0 19.6 1.4e-05 24.4 0.3 4.7 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EMG47902.1 - 2.8e-12 46.3 19.8 0.0016 18.2 2.4 4.5 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 EMG47902.1 - 9.5e-07 28.7 8.6 0.16 12.0 0.3 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EMG47902.1 - 2.2e-06 28.0 0.1 0.095 13.0 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SET PF00856.28 EMG47903.1 - 8.6e-13 49.0 0.0 1.6e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 SET domain CoaE PF01121.20 EMG47904.1 - 1.3e-42 145.5 0.0 1.4e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.6 EMG47904.1 - 0.0011 19.4 0.0 0.0011 19.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMG47904.1 - 0.0011 19.5 0.1 0.0015 19.0 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMG47904.1 - 0.0042 17.2 0.0 0.0084 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EMG47904.1 - 0.02 15.1 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.6 EMG47904.1 - 0.03 14.6 0.0 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 EMG47904.1 - 0.05 13.7 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase-like family dNK PF01712.19 EMG47904.1 - 0.069 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase PRK PF00485.18 EMG47904.1 - 0.088 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family tRNA_lig_kinase PF08303.11 EMG47904.1 - 0.12 12.4 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 tRNA ligase kinase domain Cytidylate_kin PF02224.18 EMG47904.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Cpn60_TCP1 PF00118.24 EMG47905.1 - 5e-170 566.3 3.8 5.7e-170 566.1 3.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RINT1_TIP1 PF04437.13 EMG47906.1 - 6.3e-118 394.8 20.9 6.3e-118 394.8 20.9 2.1 2 1 0 2 2 2 1 RINT-1 / TIP-1 family DUF4107 PF13389.6 EMG47906.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) Erf4 PF10256.9 EMG47906.1 - 1.2 9.3 5.6 12 6.0 0.0 3.7 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family Pkinase PF00069.25 EMG47907.1 - 4.8e-67 226.1 0.0 7.6e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG47907.1 - 1.1e-35 123.2 0.0 1.5e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EMG47907.1 - 9.4e-13 48.3 0.4 2.4e-12 47.0 0.4 1.8 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 EMG47907.1 - 1.5e-05 24.0 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EMG47907.1 - 0.0004 19.8 0.3 2 7.7 0.2 3.2 2 1 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 EMG47907.1 - 0.00079 19.7 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 EMG47907.1 - 0.0045 17.2 0.0 0.019 15.2 0.0 2.0 2 0 0 2 2 2 1 FHA domain Kdo PF06293.14 EMG47907.1 - 0.04 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_8 PF13181.6 EMG47908.1 - 0.014 15.5 2.4 0.32 11.3 0.5 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMG47908.1 - 0.029 14.5 4.7 0.87 9.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMG47908.1 - 0.031 14.9 0.0 0.12 13.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMG47908.1 - 0.12 13.1 0.4 3.6 8.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Homeodomain PF00046.29 EMG47909.1 - 3.8e-15 55.5 3.0 1e-14 54.1 3.0 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EMG47909.1 - 0.041 13.8 0.5 0.12 12.3 0.5 1.8 1 0 0 1 1 1 0 Homeobox KN domain PI_PP_I PF18363.1 EMG47909.1 - 5.7 7.2 11.3 6.3 7.1 5.5 3.7 3 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain GTP_EFTU PF00009.27 EMG47911.1 - 0.00038 20.0 0.0 0.00045 19.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Peptidase_M16_C PF05193.21 EMG47912.1 - 3.5e-15 56.5 0.4 7.6e-15 55.4 0.1 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EMG47912.1 - 2.9e-07 30.6 0.6 0.00026 21.0 0.1 2.8 1 1 2 3 3 3 2 Insulinase (Peptidase family M16) G-alpha PF00503.20 EMG47913.1 - 3.3e-109 365.3 8.6 4e-109 365.0 8.6 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EMG47913.1 - 4.1e-15 55.7 1.8 9.9e-11 41.4 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMG47913.1 - 1.4e-05 24.6 3.4 0.00015 21.2 0.2 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EMG47913.1 - 0.03 13.9 0.2 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Ras family Roc PF08477.13 EMG47913.1 - 0.038 14.2 0.4 3.7 7.8 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EMG47913.1 - 0.093 12.3 1.1 0.8 9.2 0.0 2.7 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMG47913.1 - 0.12 12.5 0.1 6 7.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EMG47913.1 - 0.16 11.7 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Metallophos PF00149.28 EMG47914.1 - 2.9e-14 54.1 0.2 5.3e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3791 PF12668.7 EMG47914.1 - 0.02 14.9 0.7 0.91 9.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) Metallophos_2 PF12850.7 EMG47914.1 - 0.057 13.6 0.0 0.09 13.0 0.0 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SKG6 PF08693.10 EMG47914.1 - 0.48 9.9 2.3 1.2 8.6 2.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Cyclin_N PF00134.23 EMG47916.1 - 3.8e-07 29.9 0.4 6e-07 29.3 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EMG47916.1 - 0.00034 21.0 1.4 0.00045 20.6 1.4 1.2 1 0 0 1 1 1 1 Cyclin IL15 PF02372.15 EMG47916.1 - 0.37 10.8 6.6 2.2 8.3 1.4 2.4 1 1 1 2 2 2 0 Interleukin 15 Pan3_PK PF18101.1 EMG47917.1 - 1.8e-35 121.9 6.8 3.5e-35 121.0 6.8 1.5 1 0 0 1 1 1 1 Pan3 Pseudokinase domain DUF966 PF06136.13 EMG47917.1 - 2.6 7.7 9.8 4.9 6.8 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CybS PF05328.12 EMG47918.1 - 2.9e-59 198.5 0.2 3.4e-59 198.3 0.2 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Strep_SA_rep PF06696.11 EMG47919.1 - 0.062 13.3 0.6 0.14 12.2 0.6 1.6 1 0 0 1 1 1 0 Streptococcal surface antigen repeat PPP4R2 PF09184.11 EMG47920.1 - 0.0092 15.6 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 PPP4R2 DUF1870 PF08965.10 EMG47920.1 - 0.028 14.5 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) Ribosomal_S7 PF00177.21 EMG47921.1 - 1.5e-37 128.6 2.4 2.4e-37 127.9 2.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Spa1_C PF18218.1 EMG47921.1 - 0.0083 16.5 0.3 0.31 11.5 0.1 2.3 2 0 0 2 2 2 1 Lantibiotic immunity protein Spa1 C-terminal domain HisG PF01634.18 EMG47923.1 - 4.6e-54 182.7 0.0 7.5e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EMG47923.1 - 7.6e-27 93.3 0.1 1.3e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain Proteasome PF00227.26 EMG47924.1 - 1.3e-38 132.5 0.1 1.4e-38 132.3 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Lum_binding PF00677.17 EMG47925.1 - 1.6e-42 143.4 5.4 1.9e-21 75.8 0.4 2.3 2 0 0 2 2 2 2 Lumazine binding domain Ribosomal_S14 PF00253.21 EMG47926.1 - 7.3e-21 73.7 0.2 2e-20 72.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e GPCR_chapero_1 PF11904.8 EMG47926.1 - 0.012 15.1 0.1 0.012 15.1 0.1 1.1 1 0 0 1 1 1 0 GPCR-chaperone FAS_N PF17828.1 EMG47926.1 - 0.032 14.3 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta LRR_8 PF13855.6 EMG47927.1 - 0.00023 20.9 13.3 0.13 12.1 0.1 5.4 4 1 1 5 5 5 4 Leucine rich repeat LRR_5 PF13306.6 EMG47927.1 - 0.17 11.8 7.1 0.16 12.0 0.5 3.3 3 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Prenyltransf PF01255.19 EMG47928.1 - 3.8e-74 249.0 0.0 4.6e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase HSF_DNA-bind PF00447.17 EMG47929.1 - 8.6e-26 90.4 0.9 2.3e-25 89.0 0.9 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding Mss4 PF04421.13 EMG47930.1 - 5.1e-14 52.2 0.0 6.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Mss4 protein zf-RAG1 PF10426.9 EMG47930.1 - 0.46 10.7 0.1 0.46 10.7 0.1 2.5 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain NOP19 PF10863.8 EMG47932.1 - 1.3e-16 60.7 15.7 1.3e-15 57.5 12.3 2.5 2 1 0 2 2 2 1 Nucleolar protein 19 DUF3245 PF11595.8 EMG47932.1 - 0.0066 16.9 14.3 0.012 16.1 13.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) Sporozoite_P67 PF05642.11 EMG47932.1 - 0.037 12.1 2.7 0.039 12.0 2.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ESM4 PF15952.5 EMG47932.1 - 1.7 9.0 9.2 0.27 11.6 4.3 1.8 2 0 0 2 2 2 0 Enhancer of split M4 family GRDP-like PF07173.12 EMG47933.1 - 3e-24 86.3 7.4 4.7e-22 79.2 0.1 3.1 2 1 1 3 3 3 2 Glycine-rich domain-containing protein-like Recep_L_domain PF01030.24 EMG47934.1 - 2.2e-06 27.7 17.9 0.02 15.0 0.6 4.2 2 2 1 4 4 4 4 Receptor L domain LRR_9 PF14580.6 EMG47934.1 - 0.09 12.3 5.8 0.12 11.8 4.6 1.9 1 1 1 2 2 2 0 Leucine-rich repeat Macoilin PF09726.9 EMG47934.1 - 1.8 7.0 5.5 2.4 6.6 5.5 1.2 1 0 0 1 1 1 0 Macoilin family AF-4 PF05110.13 EMG47934.1 - 5.9 4.8 18.4 7.7 4.4 18.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LRR_4 PF12799.7 EMG47935.1 - 3.1e-13 49.7 9.4 0.21 12.1 0.4 7.6 5 2 2 7 7 7 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EMG47935.1 - 2.3e-10 40.2 1.6 5.1e-10 39.1 1.6 1.6 1 0 0 1 1 1 1 F-box-like DUF1699 PF08004.11 EMG47935.1 - 0.00054 19.7 0.4 12 5.5 0.1 4.8 4 0 0 4 4 4 1 Protein of unknown function (DUF1699) F-box PF00646.33 EMG47935.1 - 0.0016 18.3 1.1 0.0046 16.8 0.2 2.3 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 EMG47935.1 - 0.1 12.7 18.8 5.9 7.2 0.0 8.4 11 0 0 11 11 11 0 Leucine Rich repeat PCI PF01399.27 EMG47936.1 - 1.4e-07 32.0 0.9 1e-06 29.2 0.3 2.6 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.17 EMG47936.1 - 0.027 14.6 0.5 0.15 12.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMG47936.1 - 0.077 13.3 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMG47936.1 - 0.23 11.7 3.0 5 7.6 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PUF PF00806.19 EMG47937.1 - 3.3e-22 76.9 3.1 1.1e-05 24.8 0.0 6.5 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat eIF-5_eIF-2B PF01873.17 EMG47938.1 - 3.6e-39 133.3 0.0 6.5e-39 132.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Fip1 PF05182.13 EMG47939.1 - 1.3e-21 75.8 0.1 2.9e-21 74.7 0.1 1.6 1 0 0 1 1 1 1 Fip1 motif Sporozoite_P67 PF05642.11 EMG47939.1 - 0.15 10.1 15.1 0.19 9.8 15.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myc_N PF01056.18 EMG47939.1 - 0.49 10.2 11.0 0.7 9.7 11.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PI3K_1B_p101 PF10486.9 EMG47939.1 - 1.6 6.4 6.3 2 6.1 6.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 EMG47939.1 - 3.3 6.4 6.2 4.1 6.1 6.2 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EMG47939.1 - 3.9 5.7 13.1 4.7 5.4 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein GRDP-like PF07173.12 EMG47940.1 - 9.7e-25 87.9 7.6 1.6e-22 80.7 0.1 3.2 4 0 0 4 4 4 2 Glycine-rich domain-containing protein-like PH PF00169.29 EMG47941.1 - 2.6e-10 40.7 0.1 2.6e-10 40.7 0.1 2.6 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 EMG47941.1 - 0.033 14.6 0.1 0.3 11.5 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain gpW PF02831.15 EMG47941.1 - 0.036 14.0 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 gpW RRM_1 PF00076.22 EMG47942.1 - 0.00022 21.0 0.3 0.00063 19.5 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ESCRT-II PF05871.12 EMG47943.1 - 8.3e-44 149.2 0.3 2.5e-43 147.7 0.2 1.7 2 0 0 2 2 2 1 ESCRT-II complex subunit Ribosomal_L9_N PF01281.19 EMG47943.1 - 0.012 15.2 0.1 13 5.5 0.0 3.1 3 0 0 3 3 3 0 Ribosomal protein L9, N-terminal domain CAP59_mtransfer PF11735.8 EMG47943.1 - 0.11 12.2 0.7 1.9 8.1 0.2 2.0 2 0 0 2 2 2 0 Cryptococcal mannosyltransferase 1 Ribosomal_L37ae PF01780.19 EMG47944.1 - 4.9e-39 132.3 9.7 5.8e-39 132.1 9.7 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 EMG47944.1 - 0.0034 17.3 4.2 0.0061 16.5 4.2 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 EMG47944.1 - 0.0056 17.0 0.4 1.9 9.1 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-RING_13 PF17977.1 EMG47944.1 - 0.007 16.5 1.9 0.0094 16.1 1.9 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain CarbpepA_inh PF02977.15 EMG47944.1 - 0.13 12.1 0.8 0.13 12.1 0.8 2.0 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor C1_2 PF03107.16 EMG47944.1 - 0.27 11.6 2.3 2 8.8 2.4 1.9 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 EMG47944.1 - 0.61 10.2 4.6 5.3 7.2 0.2 2.4 1 1 1 2 2 2 0 BED zinc finger zf-C4_ClpX PF06689.13 EMG47944.1 - 2.6 8.0 4.9 10 6.1 4.9 2.1 1 1 0 1 1 1 0 ClpX C4-type zinc finger Arginase PF00491.21 EMG47946.1 - 2.4e-70 237.2 0.0 2.8e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family GDPD PF03009.17 EMG47947.1 - 4.9e-71 239.5 2.0 6.6e-71 239.1 0.4 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EMG47947.1 - 4.8e-27 94.4 0.5 1.3e-09 38.5 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMG47947.1 - 1.1e-20 73.8 0.1 4.5e-06 27.1 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMG47947.1 - 5.8e-17 60.1 0.4 0.00082 19.6 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EMG47947.1 - 6.8e-16 57.9 0.5 0.0049 17.3 0.0 6.0 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EMG47947.1 - 4.7e-15 55.5 1.1 0.0014 18.9 0.1 4.8 3 1 0 4 4 4 3 Ankyrin repeats (many copies) SPX PF03105.19 EMG47947.1 - 3.3e-11 43.7 9.6 1.8e-10 41.3 0.9 5.0 4 1 2 6 6 6 3 SPX domain TIP41 PF04176.13 EMG47948.1 - 2e-67 226.0 0.1 3.7e-67 225.1 0.1 1.5 1 0 0 1 1 1 1 TIP41-like family Sod_Fe_C PF02777.18 EMG47948.1 - 1.2e-12 47.9 4.6 2e-10 40.7 4.6 2.4 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain PRF PF06875.11 EMG47949.1 - 0.0033 16.9 0.4 0.0051 16.3 0.4 1.3 1 0 0 1 1 1 1 Plethodontid receptivity factor PRF TPR_2 PF07719.17 EMG47950.1 - 0.00037 20.4 0.0 0.002 18.1 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMG47950.1 - 0.00096 19.2 1.1 0.0043 17.2 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMG47950.1 - 0.0035 17.8 0.1 0.091 13.3 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMG47950.1 - 0.0073 16.1 0.1 0.027 14.3 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMG47950.1 - 0.044 13.5 1.4 0.13 12.0 1.4 1.9 1 0 0 1 1 1 0 TPR repeat TPR_17 PF13431.6 EMG47950.1 - 0.069 13.6 0.8 2.9 8.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat CTP_synth_N PF06418.14 EMG47952.1 - 3.3e-124 413.5 1.0 3.9e-124 413.2 0.4 1.5 2 0 0 2 2 2 1 CTP synthase N-terminus GATase PF00117.28 EMG47952.1 - 6.3e-55 185.9 0.0 9.9e-55 185.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EMG47952.1 - 2.5e-06 27.4 0.1 3.4e-05 23.7 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 Phage_tail_3 PF08813.11 EMG47952.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein, TTP MFS_1 PF07690.16 EMG47953.1 - 3.9e-25 88.5 28.3 7e-16 58.1 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMG47953.1 - 1.4e-14 53.5 25.4 2e-11 43.1 7.0 2.7 1 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EMG47953.1 - 7.5e-07 28.3 9.0 7.5e-07 28.3 9.0 2.2 1 1 1 2 2 2 1 MFS_1 like family Sugar_tr PF00083.24 EMG47953.1 - 1.7e-05 23.9 23.6 0.00016 20.6 23.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EMG47953.1 - 0.0013 17.1 2.4 0.0013 17.1 2.4 3.0 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EMG47953.1 - 0.091 11.1 2.1 2.2 6.6 0.1 2.4 2 0 0 2 2 2 0 Transmembrane secretion effector Metallophos PF00149.28 EMG47954.1 - 8.4e-07 29.7 5.9 1.2e-06 29.2 3.2 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Peptidase_C12 PF01088.21 EMG47956.1 - 7.3e-63 212.1 0.1 1.3e-62 211.3 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EMG47956.1 - 8.2e-11 41.6 2.2 1.8e-10 40.6 2.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Mito_carr PF00153.27 EMG47957.1 - 4.4e-72 238.1 1.0 3.6e-24 84.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ran_BP1 PF00638.18 EMG47959.1 - 3.4e-21 75.7 0.1 6.4e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 EMG47959.1 - 1.9e-14 54.0 0.1 1.9e-14 54.0 0.1 6.5 5 3 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) WH1 PF00568.23 EMG47959.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 WH1 domain RabGAP-TBC PF00566.18 EMG47960.1 - 2.3e-06 27.4 13.0 2.3e-06 27.4 13.0 3.7 4 1 1 5 5 5 1 Rab-GTPase-TBC domain ABC_tran PF00005.27 EMG47961.1 - 2e-46 157.9 0.0 1.5e-23 83.8 0.0 4.3 3 2 0 3 3 2 2 ABC transporter 4HB PF17947.1 EMG47961.1 - 6.2e-29 99.9 0.1 2.6e-28 97.9 0.1 2.2 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 EMG47961.1 - 1e-16 61.7 1.0 0.0045 16.9 0.0 4.5 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMG47961.1 - 8.4e-15 54.8 0.2 3.6e-05 23.3 0.0 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMG47961.1 - 1.2e-10 42.2 8.8 0.00023 21.7 0.0 3.9 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 EMG47961.1 - 3.8e-09 36.7 0.0 0.00036 20.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EMG47961.1 - 1.3e-08 34.5 0.0 0.0077 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 EMG47961.1 - 6.7e-08 33.0 0.1 0.0021 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EMG47961.1 - 8.8e-08 32.2 0.0 0.0026 17.8 0.0 3.5 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EMG47961.1 - 1e-06 29.0 0.0 0.036 14.3 0.0 3.5 4 0 0 4 4 2 2 AAA domain RNA_helicase PF00910.22 EMG47961.1 - 7.1e-06 26.4 0.0 0.19 12.2 0.0 3.4 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.6 EMG47961.1 - 1.2e-05 25.9 0.3 0.29 11.7 0.0 3.6 4 0 0 4 4 2 2 AAA domain Dynamin_N PF00350.23 EMG47961.1 - 1.7e-05 25.0 0.0 0.0008 19.5 0.0 3.0 2 0 0 2 2 2 1 Dynamin family AAA PF00004.29 EMG47961.1 - 3.3e-05 24.3 0.8 0.76 10.2 0.0 4.5 5 0 0 5 5 3 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 EMG47961.1 - 7.3e-05 21.9 0.0 0.21 10.6 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EMG47961.1 - 0.00012 22.3 0.0 0.67 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EMG47961.1 - 0.00018 21.9 0.1 0.23 11.8 0.0 3.3 4 0 0 4 4 3 1 AAA ATPase domain AAA_27 PF13514.6 EMG47961.1 - 0.0002 21.0 0.0 0.2 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMG47961.1 - 0.00043 20.0 0.0 1.3 8.7 0.0 3.7 3 1 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 EMG47961.1 - 0.00064 19.5 0.0 0.12 12.1 0.0 3.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EMG47961.1 - 0.0018 18.0 0.1 1.7 8.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 EMG47961.1 - 0.0019 18.4 0.0 0.79 10.0 0.0 3.5 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 EMG47961.1 - 0.0038 17.3 0.0 8.1 6.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain Adaptin_N PF01602.20 EMG47961.1 - 0.004 15.8 5.5 0.018 13.6 5.5 1.9 1 1 0 1 1 1 1 Adaptin N terminal region NACHT PF05729.12 EMG47961.1 - 0.0046 16.9 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 EMG47961.1 - 0.0047 16.5 0.1 3.7 7.1 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EMG47961.1 - 0.0055 16.6 0.0 7.5 6.4 0.0 3.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 EMG47961.1 - 0.0059 16.5 0.0 3 7.7 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain CLP1_P PF16575.5 EMG47961.1 - 0.0094 15.8 0.1 1.8 8.3 0.0 3.2 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 EMG47961.1 - 0.01 15.6 0.0 3.8 7.2 0.0 3.2 3 0 0 3 3 2 0 IstB-like ATP binding protein HEAT_2 PF13646.6 EMG47961.1 - 0.012 15.9 1.5 0.084 13.3 1.0 2.6 1 1 1 2 2 2 0 HEAT repeats Ploopntkinase3 PF18751.1 EMG47961.1 - 0.018 14.9 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 HEAT_EZ PF13513.6 EMG47961.1 - 0.019 15.5 5.7 2.6 8.6 0.1 4.5 4 1 2 6 6 3 0 HEAT-like repeat Roc PF08477.13 EMG47961.1 - 0.022 15.0 0.0 13 6.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cytidylate_kin PF02224.18 EMG47961.1 - 0.023 14.4 0.0 9.7 5.9 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase ATP_bind_1 PF03029.17 EMG47961.1 - 0.042 13.6 0.2 8.6 6.1 0.0 3.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 EMG47961.1 - 0.044 13.1 0.5 3.7 6.8 0.0 3.1 3 1 0 3 3 2 0 Septin DUF87 PF01935.17 EMG47961.1 - 0.049 13.7 8.4 0.38 10.8 0.0 4.4 5 1 1 6 6 4 0 Helicase HerA, central domain NTPase_1 PF03266.15 EMG47961.1 - 0.049 13.5 0.1 18 5.2 0.0 3.0 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 EMG47961.1 - 0.051 12.9 0.1 1.6 8.0 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI CLASP_N PF12348.8 EMG47961.1 - 0.056 13.0 0.4 9.4 5.7 0.1 2.8 2 1 0 3 3 3 0 CLASP N terminal FtsK_SpoIIIE PF01580.18 EMG47961.1 - 0.056 12.8 0.8 7.4 5.8 0.0 3.4 4 0 0 4 4 4 0 FtsK/SpoIIIE family UME PF08064.13 EMG47961.1 - 0.059 13.3 0.3 0.17 11.8 0.3 1.8 1 0 0 1 1 1 0 UME (NUC010) domain AAA_7 PF12775.7 EMG47961.1 - 0.06 12.9 0.0 14 5.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 EMG47961.1 - 0.062 13.3 0.0 6.1 6.9 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MutS_V PF00488.21 EMG47961.1 - 0.078 13.0 0.1 6.4 6.7 0.1 2.6 2 0 0 2 2 2 0 MutS domain V MukB PF04310.12 EMG47961.1 - 0.09 12.6 0.1 11 5.8 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal AAA_13 PF13166.6 EMG47961.1 - 0.093 11.4 8.6 1.7 7.2 0.0 4.0 5 0 0 5 5 5 0 AAA domain Zeta_toxin PF06414.12 EMG47961.1 - 0.098 11.9 0.2 14 4.9 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin MMS19_N PF14500.6 EMG47961.1 - 0.51 9.9 2.8 12 5.4 0.1 3.1 2 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II AAA_15 PF13175.6 EMG47961.1 - 0.92 9.1 16.0 0.7 9.5 0.2 4.2 4 2 0 4 4 3 0 AAA ATPase domain AAA_17 PF13207.6 EMG47961.1 - 2.4 8.6 6.7 36 4.8 0.6 4.4 4 1 0 4 4 2 0 AAA domain Acetyltransf_7 PF13508.7 EMG47962.1 - 0.053 14.0 0.6 0.42 11.1 0.7 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMG47962.1 - 0.077 13.2 0.1 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family LRR_8 PF13855.6 EMG47963.1 - 4.3e-15 55.2 8.0 5.9e-10 38.8 0.5 5.5 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EMG47963.1 - 1e-09 38.5 35.2 0.0019 18.6 2.0 9.9 7 1 5 12 12 12 7 Leucine Rich repeats (2 copies) FNIP PF05725.12 EMG47963.1 - 0.00048 20.2 16.5 1.6 9.0 0.0 7.5 6 2 1 7 7 7 3 FNIP Repeat LRR_1 PF00560.33 EMG47963.1 - 0.011 16.1 6.3 1 10.2 0.6 6.2 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_5 PF13306.6 EMG47963.1 - 0.023 14.6 14.9 0.22 11.5 0.7 4.4 4 0 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EMG47963.1 - 0.29 11.3 10.4 45 4.5 0.3 6.1 6 0 0 6 6 6 0 Leucine Rich repeat LRR_9 PF14580.6 EMG47963.1 - 0.42 10.1 3.1 8 5.9 0.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeat LRR_8 PF13855.6 EMG47964.1 - 8.3e-15 54.3 8.1 7.6e-09 35.2 0.0 5.9 5 0 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EMG47964.1 - 3.5e-09 36.8 29.1 9.2e-05 22.7 1.9 9.6 5 2 7 12 12 12 4 Leucine Rich repeats (2 copies) FNIP PF05725.12 EMG47964.1 - 1.5e-06 28.3 13.9 0.24 11.6 0.4 7.8 6 3 1 7 7 7 4 FNIP Repeat LRR_1 PF00560.33 EMG47964.1 - 1 10.2 16.5 5.7 7.9 0.7 7.3 7 2 0 7 7 7 0 Leucine Rich Repeat F-box-like PF12937.7 EMG47964.1 - 1.1 9.2 3.1 0.84 9.6 0.5 2.2 2 0 0 2 2 2 0 F-box-like LRR_6 PF13516.6 EMG47964.1 - 7.4 6.9 18.5 4.8 7.5 0.1 6.6 10 0 0 10 10 10 0 Leucine Rich repeat AA_permease PF00324.21 EMG47965.1 - 5.6e-119 397.9 37.2 6.6e-119 397.6 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG47965.1 - 2.8e-35 122.0 37.5 3.4e-35 121.7 37.5 1.1 1 0 0 1 1 1 1 Amino acid permease VASP_tetra PF08776.11 EMG47965.1 - 0.089 12.4 2.0 0.15 11.7 2.0 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain PH_9 PF15410.6 EMG47966.1 - 1.4e-06 28.7 0.2 5.1e-06 26.8 0.2 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EMG47966.1 - 0.00017 22.1 5.5 0.00043 20.7 0.1 3.6 3 1 0 3 3 3 1 PH domain Senescence_reg PF04520.13 EMG47966.1 - 3.1 8.6 12.0 2.7 8.8 7.6 2.2 2 0 0 2 2 2 0 Senescence regulator Ig_4 PF16680.5 EMG47967.1 - 0.048 13.9 0.1 0.15 12.4 0.1 1.8 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 EMG47967.1 - 0.053 13.9 0.1 0.17 12.3 0.1 1.9 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Polyketide_cyc PF03364.20 EMG47968.1 - 4.6e-14 52.7 0.0 5.3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EMG47968.1 - 0.014 15.7 0.0 0.019 15.3 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Ribosomal_S25 PF03297.15 EMG47969.1 - 2.8e-39 133.4 4.7 3.1e-39 133.2 4.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 EMG47969.1 - 0.00012 21.8 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain EAP30 PF04157.16 EMG47969.1 - 0.014 14.7 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family DUF365 PF04033.12 EMG47969.1 - 0.05 13.9 0.3 0.072 13.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Tctex-1 PF03645.13 EMG47969.1 - 0.068 13.4 0.0 0.076 13.2 0.0 1.1 1 0 0 1 1 1 0 Tctex-1 family HTH_24 PF13412.6 EMG47969.1 - 0.07 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_CodY PF08222.11 EMG47969.1 - 0.07 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain PLA2_B PF01735.18 EMG47970.1 - 8.7e-111 370.7 18.2 1.6e-86 290.7 8.3 3.0 1 1 1 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.22 EMG47970.1 - 0.0022 18.2 0.0 0.0068 16.6 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Kri1_C PF12936.7 EMG47970.1 - 0.079 13.1 0.1 0.99 9.6 0.1 2.3 2 0 0 2 2 2 0 KRI1-like family C-terminal Glutaredoxin PF00462.24 EMG47971.1 - 1.6e-11 44.2 0.0 2.8e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EMG47971.1 - 0.096 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_S17_N PF16205.5 EMG47972.1 - 1.3e-31 108.8 0.7 2.5e-31 107.9 0.7 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EMG47972.1 - 5.5e-27 93.7 1.9 5.5e-27 93.7 1.9 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 ANAPC9 PF12856.7 EMG47973.1 - 7.4e-40 135.8 1.2 7.4e-40 135.8 1.2 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 9 Androgen_recep PF02166.16 EMG47973.1 - 1.2 7.9 4.0 1.9 7.2 4.0 1.3 1 0 0 1 1 1 0 Androgen receptor Pyr_redox_2 PF07992.14 EMG47974.1 - 3.5e-56 190.6 2.0 6.3e-56 189.8 2.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EMG47974.1 - 1.2e-31 109.2 0.2 9.5e-31 106.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EMG47974.1 - 2.6e-19 69.6 5.6 8.3e-17 61.5 1.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMG47974.1 - 3.2e-10 39.3 0.6 0.0015 17.3 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 EMG47974.1 - 4.8e-08 32.6 5.7 6.4e-06 25.6 0.6 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMG47974.1 - 1.8e-07 30.9 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EMG47974.1 - 1.1e-05 24.7 0.1 1.1e-05 24.7 0.1 2.9 3 1 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EMG47974.1 - 0.00076 19.7 0.6 0.00076 19.7 0.6 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMG47974.1 - 0.0008 18.6 1.0 0.0026 16.9 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EMG47974.1 - 0.00081 18.7 0.4 0.04 13.2 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EMG47974.1 - 0.0017 18.0 0.0 0.0017 18.0 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EMG47974.1 - 0.0018 17.7 1.2 0.98 8.7 0.1 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 EMG47974.1 - 0.0032 16.7 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EMG47974.1 - 0.0053 16.0 0.1 0.022 14.0 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 EMG47974.1 - 0.013 15.9 0.2 0.19 12.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EMG47974.1 - 0.041 13.1 0.8 0.62 9.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EMG47974.1 - 0.12 12.0 1.9 0.43 10.1 0.3 2.6 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EMG47974.1 - 0.12 12.3 6.0 0.51 10.2 0.1 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3888 PF13027.6 EMG47974.1 - 0.19 12.2 1.7 0.42 11.1 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) Zn_clus PF00172.18 EMG47975.1 - 4.4e-09 36.3 6.8 1.1e-08 35.0 6.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3450 PF11932.8 EMG47975.1 - 3.1 7.1 5.3 0.96 8.7 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ABC1 PF03109.16 EMG47976.1 - 1.6e-34 118.6 0.4 3.6e-34 117.5 0.1 1.8 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.22 EMG47976.1 - 0.002 17.8 0.1 0.022 14.3 0.0 2.4 3 0 0 3 3 3 1 RIO1 family rRNA_processing PF08524.11 EMG47977.1 - 2.8e-41 141.0 24.4 3.2e-41 140.8 24.4 1.0 1 0 0 1 1 1 1 rRNA processing CDC45 PF02724.14 EMG47977.1 - 4.8 5.3 12.0 5.4 5.2 12.0 1.2 1 0 0 1 1 1 0 CDC45-like protein S36_mt PF10937.8 EMG47978.1 - 2e-05 26.1 3.0 9.5e-05 24.0 2.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S36, mitochondrial UCH PF00443.29 EMG47979.1 - 2.4 7.6 5.9 0.35 10.3 1.3 1.7 1 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF410 PF04190.13 EMG47980.1 - 1.9e-51 175.3 0.5 2.5e-51 174.9 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RPN6_N PF18055.1 EMG47980.1 - 0.0012 19.1 2.8 0.0075 16.6 1.0 2.5 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain Endopep_inhib PF16800.5 EMG47980.1 - 0.042 13.8 1.8 0.086 12.8 1.8 1.5 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor NUDIX PF00293.28 EMG47981.1 - 8.6e-15 54.9 0.1 1e-14 54.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain WD40 PF00400.32 EMG47982.1 - 1.1 10.2 5.3 3.2 8.8 0.0 4.1 5 0 0 5 5 5 0 WD domain, G-beta repeat Zn_clus PF00172.18 EMG47983.1 - 1.7e-08 34.4 11.6 3.2e-08 33.5 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rad9_Rad53_bind PF08605.10 EMG47984.1 - 1.5e-27 96.3 0.5 3.2e-27 95.3 0.5 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 EMG47984.1 - 5.2e-08 33.2 2.6 8.8e-06 26.0 0.1 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EMG47984.1 - 3e-05 24.3 0.9 0.00052 20.4 0.0 3.0 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EMG47984.1 - 0.03 14.2 0.1 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 EMG47984.1 - 0.079 13.0 0.1 0.34 11.0 0.1 2.2 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_6 PF16771.5 EMG47984.1 - 3.2 8.0 8.1 0.7 10.1 2.9 2.4 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Pro_dh PF01619.18 EMG47985.1 - 1e-62 212.3 2.0 1.3e-62 212.0 2.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase HSP9_HSP12 PF04119.12 EMG47986.1 - 3.2e-26 91.5 3.1 3.2e-26 91.5 3.1 2.5 2 1 0 2 2 2 1 Heat shock protein 9/12 DUF883 PF05957.13 EMG47986.1 - 0.02 15.5 3.6 0.037 14.6 2.9 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Mt_ATP-synt_B PF05405.14 EMG47986.1 - 0.091 12.4 2.5 6.5 6.3 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SNARE PF05739.19 EMG47986.1 - 0.11 12.6 4.0 0.13 12.3 0.0 3.0 4 0 0 4 4 4 0 SNARE domain Grg1 PF11034.8 EMG47986.1 - 0.61 10.3 16.8 2.4 8.4 0.2 3.5 1 1 2 3 3 3 0 Glucose-repressible protein Grg1 YtxH PF12732.7 EMG47986.1 - 0.71 10.5 14.7 4.7e+02 1.4 14.7 2.7 1 1 0 1 1 1 0 YtxH-like protein ATP-synt_B PF00430.18 EMG47986.1 - 0.75 9.9 6.3 0.64 10.1 4.0 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) MT0933_antitox PF14013.6 EMG47986.1 - 1.1 9.7 16.8 1.9e+02 2.4 1.6 3.6 2 1 1 3 3 3 0 MT0933-like antitoxin protein AAA PF00004.29 EMG47987.1 - 3e-96 318.9 0.2 1.3e-48 164.8 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMG47987.1 - 4.8e-24 83.9 0.1 1.7e-11 43.7 0.0 3.1 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 EMG47987.1 - 1.7e-15 57.2 0.0 1.6e-08 34.5 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EMG47987.1 - 3.7e-13 49.9 0.0 3.8e-05 23.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EMG47987.1 - 2.6e-11 44.2 0.4 0.0016 18.9 0.1 4.2 2 2 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 EMG47987.1 - 7.8e-11 42.3 0.0 7.2e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EMG47987.1 - 1e-10 41.8 1.1 5.7e-05 23.1 0.0 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMG47987.1 - 4.3e-10 40.0 3.7 0.0073 16.6 0.0 5.4 3 2 1 4 4 4 2 AAA domain AAA_18 PF13238.6 EMG47987.1 - 1.7e-09 38.3 0.6 4.2e-05 24.1 0.0 3.9 3 2 1 4 4 2 2 AAA domain AAA_14 PF13173.6 EMG47987.1 - 3.8e-09 36.7 0.0 0.0015 18.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EMG47987.1 - 3.9e-08 32.9 0.0 0.0016 17.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 EMG47987.1 - 6.9e-08 32.1 0.2 0.0041 16.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EMG47987.1 - 1.2e-07 32.1 0.0 0.013 15.9 0.0 3.3 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EMG47987.1 - 1.4e-07 31.9 0.0 0.0013 19.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EMG47987.1 - 2.1e-07 30.8 1.4 0.00041 20.3 0.1 3.1 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 EMG47987.1 - 2.2e-07 31.5 7.9 0.002 18.6 0.0 4.2 3 2 0 3 3 2 2 ABC transporter Cytidylate_kin2 PF13189.6 EMG47987.1 - 6.9e-07 29.6 0.0 0.00015 21.9 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family IstB_IS21 PF01695.17 EMG47987.1 - 8.9e-07 28.8 0.5 0.039 13.7 0.0 2.9 2 1 0 3 3 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 EMG47987.1 - 1.7e-06 27.5 0.1 0.049 12.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.15 EMG47987.1 - 1.8e-06 28.0 0.5 0.011 15.7 0.0 3.1 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_25 PF13481.6 EMG47987.1 - 4.8e-06 26.3 1.3 0.23 11.0 0.1 4.1 3 1 1 4 4 4 1 AAA domain AAA_3 PF07726.11 EMG47987.1 - 6e-06 26.1 0.0 0.033 14.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EMG47987.1 - 6.6e-06 26.6 1.3 0.011 16.2 0.0 3.4 3 1 1 4 4 2 1 AAA domain NACHT PF05729.12 EMG47987.1 - 1.2e-05 25.3 0.0 0.092 12.7 0.0 3.2 3 0 0 3 3 3 2 NACHT domain ATPase_2 PF01637.18 EMG47987.1 - 1.7e-05 24.9 0.2 0.27 11.1 0.0 4.2 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea TsaE PF02367.17 EMG47987.1 - 3.2e-05 23.9 0.0 0.079 13.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 EMG47987.1 - 6.8e-05 23.0 0.0 0.084 13.0 0.0 2.9 2 0 0 2 2 2 1 Shikimate kinase AAA_7 PF12775.7 EMG47987.1 - 7.5e-05 22.3 0.0 0.37 10.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 EMG47987.1 - 0.00016 20.9 0.0 0.058 12.5 0.0 2.7 3 0 0 3 3 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EMG47987.1 - 0.00016 21.4 0.0 0.25 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EMG47987.1 - 0.00019 20.9 0.3 0.84 8.9 0.0 3.4 2 1 0 3 3 3 1 KaiC NB-ARC PF00931.22 EMG47987.1 - 0.0003 20.1 0.0 1.9 7.6 0.0 3.6 4 0 0 4 4 4 2 NB-ARC domain Viral_helicase1 PF01443.18 EMG47987.1 - 0.00036 20.4 1.2 0.65 9.7 0.0 3.4 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 EMG47987.1 - 0.0005 19.8 0.0 0.43 10.3 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain PduV-EutP PF10662.9 EMG47987.1 - 0.00066 19.4 0.0 0.19 11.5 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 EMG47987.1 - 0.0027 17.2 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Parvo_NS1 PF01057.17 EMG47987.1 - 0.0037 16.4 0.0 2.9 6.9 0.0 2.5 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 EMG47987.1 - 0.004 17.3 0.0 4.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain SRPRB PF09439.10 EMG47987.1 - 0.0044 16.5 0.2 2 7.8 0.0 3.6 4 0 0 4 4 2 1 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 EMG47987.1 - 0.0045 16.9 0.0 1 9.3 0.0 2.6 2 0 0 2 2 2 1 NTPase MMR_HSR1 PF01926.23 EMG47987.1 - 0.0047 17.0 0.0 0.09 12.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 EMG47987.1 - 0.0054 16.4 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.6 EMG47987.1 - 0.0066 16.3 13.7 1.4 8.6 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.6 EMG47987.1 - 0.0096 16.3 0.6 2 8.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 EMG47987.1 - 0.01 15.8 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase Cytidylate_kin PF02224.18 EMG47987.1 - 0.018 14.8 0.2 1.4 8.6 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase Bac_DnaA PF00308.18 EMG47987.1 - 0.024 14.5 0.0 4.4 7.1 0.0 3.4 2 2 0 2 2 2 0 Bacterial dnaA protein FeoB_N PF02421.18 EMG47987.1 - 0.029 13.9 1.1 0.6 9.6 0.0 3.1 4 0 0 4 4 2 0 Ferrous iron transport protein B AFG1_ATPase PF03969.16 EMG47987.1 - 0.03 13.2 0.0 7.1 5.4 0.0 2.5 2 0 0 2 2 2 0 AFG1-like ATPase CPT PF07931.12 EMG47987.1 - 0.046 13.6 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 EMG47987.1 - 0.051 13.3 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ADK PF00406.22 EMG47987.1 - 0.057 13.5 0.5 3.7 7.6 0.0 2.8 3 0 0 3 3 2 0 Adenylate kinase T2SSE PF00437.20 EMG47987.1 - 0.073 12.1 0.0 2.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein KTI12 PF08433.10 EMG47987.1 - 0.15 11.5 4.7 3 7.2 0.0 4.0 4 0 0 4 4 4 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 EMG47987.1 - 0.16 11.6 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DDHD PF02862.17 EMG47987.1 - 0.17 12.1 2.2 0.37 10.9 2.2 1.5 1 0 0 1 1 1 0 DDHD domain Hydin_ADK PF17213.3 EMG47987.1 - 0.44 10.8 3.8 80 3.4 0.0 3.4 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Putative_PNPOx PF01243.20 EMG47988.1 - 3.5e-13 49.5 0.0 1.8e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EMG47988.1 - 0.00095 19.2 0.0 0.0087 16.1 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase CDC4_D PF16856.5 EMG47988.1 - 0.029 14.2 0.4 0.072 13.0 0.4 1.7 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain ORC4_C PF14629.6 EMG47989.1 - 6.2e-46 156.5 0.7 1.2e-45 155.6 0.7 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EMG47989.1 - 1e-13 52.0 0.0 1.8e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EMG47989.1 - 8.8e-08 32.3 1.3 1.8e-07 31.3 1.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 EMG47989.1 - 3.3e-06 27.6 0.2 1.3e-05 25.6 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMG47989.1 - 2.1e-05 24.8 0.0 6.2e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EMG47989.1 - 6.1e-05 22.5 0.6 0.31 10.4 0.0 3.2 2 1 1 3 3 3 2 Bacterial TniB protein AAA_14 PF13173.6 EMG47989.1 - 0.00016 21.7 2.4 0.053 13.5 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 EMG47989.1 - 0.00018 21.8 0.0 0.00062 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EMG47989.1 - 0.00056 19.5 0.0 0.0047 16.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 EMG47989.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arf PF00025.21 EMG47989.1 - 0.011 15.2 0.4 2.4 7.6 0.1 3.0 3 0 0 3 3 3 0 ADP-ribosylation factor family SRPRB PF09439.10 EMG47989.1 - 0.015 14.7 0.1 0.13 11.7 0.0 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 EMG47989.1 - 0.13 12.8 0.6 24 5.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain Phage_TAC_10 PF10963.8 EMG47989.1 - 0.18 12.0 1.9 1.9 8.7 0.1 2.5 2 0 0 2 2 2 0 Phage tail assembly chaperone RGS PF00615.19 EMG47990.1 - 3e-13 50.1 3.7 3e-13 50.1 3.7 2.7 3 1 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 EMG47990.1 - 4.1e-10 39.6 0.0 1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) eIF2_C PF09173.11 EMG47991.1 - 2.2e-34 117.6 0.4 5e-34 116.4 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EMG47991.1 - 2.1e-23 82.9 0.2 1.7e-22 79.9 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EMG47991.1 - 2.4e-11 43.9 2.2 2.6e-11 43.8 0.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMG47991.1 - 0.0026 17.8 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMG47991.1 - 0.01 15.8 0.1 0.12 12.3 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EMG47991.1 - 0.064 13.3 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SPOC PF07744.13 EMG47992.1 - 3.9e-09 36.6 0.0 7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 EMG47992.1 - 1e-05 25.3 8.5 2.2e-05 24.3 8.5 1.5 1 0 0 1 1 1 1 PHD-finger TFIIS_M PF07500.14 EMG47992.1 - 5.5e-05 23.6 0.6 0.00016 22.2 0.6 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Prok-RING_1 PF14446.6 EMG47992.1 - 0.052 13.5 2.2 0.15 12.0 2.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_9 PF13901.6 EMG47992.1 - 0.22 11.5 3.7 0.5 10.3 3.7 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 EMG47992.1 - 0.55 9.8 6.5 1.2 8.8 6.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.6 EMG47992.1 - 1.7 8.3 12.3 0.034 13.7 1.3 3.0 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain Tho2 PF11262.8 EMG47993.1 - 0.19 10.9 3.7 0.26 10.4 3.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 SNARE PF05739.19 EMG47994.1 - 6.3e-10 38.9 2.9 7.8e-10 38.6 0.1 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 EMG47994.1 - 2.6e-05 24.5 14.9 6.6e-05 23.2 6.1 2.4 2 0 0 2 2 2 2 Syntaxin-like protein DEAD_assoc PF08494.11 EMG47994.1 - 0.0053 16.6 1.0 0.0076 16.1 1.0 1.2 1 0 0 1 1 1 1 DEAD/H associated PhoU_div PF01865.16 EMG47994.1 - 0.0069 15.7 0.6 0.0069 15.7 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF47 YkuI_C PF10388.9 EMG47994.1 - 0.0097 15.7 2.3 0.0097 15.7 2.3 2.1 2 0 0 2 2 2 1 EAL-domain associated signalling protein domain DUF1664 PF07889.12 EMG47994.1 - 0.34 11.0 10.9 1.1 9.3 4.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) LPP PF04728.13 EMG47994.1 - 0.42 11.0 7.1 0.59 10.6 0.3 3.4 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Lipoprotein_2 PF00921.17 EMG47994.1 - 0.47 10.0 6.9 0.65 9.5 6.9 1.4 1 1 0 1 1 1 0 Borrelia lipoprotein MCPsignal PF00015.21 EMG47994.1 - 1 9.2 10.5 2.7 7.8 4.8 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 EMG47994.1 - 1.1 9.5 6.1 4.2 7.7 0.6 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4640 PF15480.6 EMG47994.1 - 2.5 7.8 14.5 6.3 6.5 14.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4640) Fib_alpha PF08702.10 EMG47994.1 - 2.6 8.2 17.9 0.89 9.7 3.5 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF745 PF05335.13 EMG47994.1 - 5.9 6.6 10.4 0.77 9.4 0.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF2547 PF10818.8 EMG47994.1 - 6.6 7.7 14.2 0.38 11.7 5.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) WD40 PF00400.32 EMG47995.1 - 4.1e-29 100.2 20.2 4.8e-07 30.4 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG47995.1 - 1.3e-08 35.0 3.7 0.3 11.4 0.1 3.9 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain SH3_15 PF18346.1 EMG47995.1 - 0.015 15.6 0.3 0.046 14.1 0.1 2.0 2 0 0 2 2 2 0 Mind bomb SH3 repeat domain DUF1727 PF08353.10 EMG47995.1 - 0.053 13.4 2.6 18 5.3 0.0 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF1727) PPV_E2_C PF00511.17 EMG47995.1 - 0.061 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 E2 (early) protein, C terminal Kelch_2 PF07646.15 EMG47995.1 - 0.081 12.9 1.4 5.7 7.1 0.1 3.5 4 0 0 4 4 4 0 Kelch motif Coatomer_WDAD PF04053.14 EMG47995.1 - 0.2 10.7 2.2 0.39 9.7 0.6 2.0 2 1 0 2 2 2 0 Coatomer WD associated region FAD_binding_6 PF00970.24 EMG47996.1 - 1.3e-06 28.7 0.0 2.6e-05 24.5 0.0 2.4 1 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EMG47996.1 - 0.00012 22.7 0.0 0.34 11.6 0.0 2.7 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Hira PF07569.11 EMG47997.1 - 1.3e-52 178.8 0.4 3.1e-52 177.5 0.4 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EMG47997.1 - 1.8e-15 57.0 8.3 0.001 19.8 0.5 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG47997.1 - 1.2e-11 44.7 0.0 0.045 14.1 0.0 6.0 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EMG47997.1 - 9.6e-10 38.1 4.8 2.6e-09 36.7 4.8 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EMG47997.1 - 0.00011 22.1 0.3 0.37 10.8 0.1 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EMG47997.1 - 0.013 14.4 0.7 4.2 6.2 0.0 3.7 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EMG47997.1 - 0.02 14.3 8.2 0.6 9.4 0.1 4.5 5 1 0 5 5 5 0 WD40-like domain Trp_leader2 PF08056.11 EMG47997.1 - 0.21 11.6 1.6 0.61 10.1 1.6 1.7 1 0 0 1 1 1 0 Tryptophan operon leader peptide CK_II_beta PF01214.18 EMG47998.1 - 1.5e-72 243.2 0.0 2e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 EMG47998.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases tRNA-synt_1b PF00579.25 EMG47999.1 - 9.9e-71 238.4 0.0 1.3e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) GATA PF00320.27 EMG48000.1 - 0.03 13.9 0.2 0.03 13.9 0.2 2.2 2 0 0 2 2 2 0 GATA zinc finger Mannosyl_trans3 PF11051.8 EMG48001.1 - 3.7e-78 262.6 1.3 4.8e-78 262.3 1.3 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative DUF4715 PF15835.5 EMG48002.1 - 0.031 14.3 1.1 0.13 12.3 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4715) GAS PF13851.6 EMG48002.1 - 0.036 13.4 10.6 0.13 11.6 4.8 2.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mer2 PF09074.10 EMG48002.1 - 0.079 12.8 12.8 0.74 9.6 12.8 2.4 1 1 0 1 1 1 0 Mer2 AIP3 PF03915.13 EMG48002.1 - 0.1 11.7 11.0 1.1 8.3 0.7 2.0 1 1 1 2 2 2 0 Actin interacting protein 3 DUF4200 PF13863.6 EMG48002.1 - 0.12 12.7 4.9 0.26 11.7 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) SlyX PF04102.12 EMG48002.1 - 0.15 12.7 3.7 0.38 11.4 0.6 2.9 2 1 1 3 3 3 0 SlyX HemX PF04375.14 EMG48002.1 - 0.19 11.0 5.6 3.3 6.9 0.0 2.3 1 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF16 PF01519.16 EMG48002.1 - 0.23 12.0 12.5 0.24 11.9 4.1 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 ADIP PF11559.8 EMG48002.1 - 0.3 11.2 8.8 0.26 11.4 2.2 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Cob_adeno_trans PF01923.18 EMG48002.1 - 0.96 9.6 4.4 7.6 6.6 0.9 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF1664 PF07889.12 EMG48002.1 - 2.2 8.3 12.2 2.1 8.4 3.6 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EMG48002.1 - 2.4 8.3 8.9 6.4 7.0 3.4 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) KxDL PF10241.9 EMG48002.1 - 3.2 8.1 9.9 10 6.4 2.7 3.3 2 2 0 2 2 2 0 Uncharacterized conserved protein Laminin_II PF06009.12 EMG48002.1 - 3.3 7.7 8.1 0.99 9.4 2.0 2.7 1 1 1 3 3 3 0 Laminin Domain II Aldolase_II PF00596.21 EMG48003.1 - 2.6e-43 148.1 0.0 3.5e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GATase_2 PF00310.21 EMG48003.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Pyr_redox_2 PF07992.14 EMG48004.1 - 3e-52 177.7 0.3 3.4e-52 177.5 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMG48004.1 - 2.1e-18 66.7 0.1 4.3e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMG48004.1 - 8.5e-17 61.5 0.5 1.6e-14 54.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMG48004.1 - 0.00043 19.5 4.3 0.56 9.2 0.2 3.8 3 1 1 4 4 4 2 Glucose inhibited division protein A Thi4 PF01946.17 EMG48004.1 - 0.0026 17.0 0.1 0.0085 15.4 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EMG48004.1 - 0.0034 16.5 1.3 1.4 7.9 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 EMG48004.1 - 0.0046 17.2 0.2 0.024 14.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EMG48004.1 - 0.0063 16.9 0.0 1.6 9.2 0.0 2.5 2 2 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 EMG48004.1 - 0.018 14.2 0.1 1.3 8.1 0.0 3.1 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 EMG48004.1 - 0.028 13.8 0.1 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMG48004.1 - 0.16 12.0 0.0 6.3 6.8 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 EMG48004.1 - 0.55 9.8 2.6 9.7 5.7 0.0 2.6 2 2 2 4 4 4 0 FAD dependent oxidoreductase RET_CLD1 PF17756.1 EMG48006.1 - 0.0015 18.8 0.6 0.16 12.3 0.2 2.3 2 0 0 2 2 2 2 RET Cadherin like domain 1 DUF3642 PF12182.8 EMG48006.1 - 0.016 15.5 0.2 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Bacterial lipoprotein Mtd_N PF18454.1 EMG48006.1 - 0.057 13.4 0.1 3.5 7.7 0.0 3.5 4 0 0 4 4 4 0 Major tropism determinant N-terminal domain FlgH PF02107.16 EMG48006.1 - 0.092 12.4 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Flagellar L-ring protein DUF1189 PF06691.11 EMG48006.1 - 2.3 7.7 3.4 37 3.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1189) Trypan_PARP PF05887.11 EMG48007.1 - 3.4 7.6 13.8 5.5 7.0 13.8 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mannosyl_trans3 PF11051.8 EMG48008.1 - 6.6e-82 275.0 1.1 8.7e-82 274.6 1.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative FolB PF02152.18 EMG48009.1 - 0.19 12.3 2.4 2.4 8.8 0.2 2.6 2 0 0 2 2 2 0 Dihydroneopterin aldolase Usp PF00582.26 EMG48010.1 - 0.011 16.3 0.0 0.2 12.2 0.0 2.5 1 1 0 1 1 1 0 Universal stress protein family Cytochrome-c551 PF10643.9 EMG48010.1 - 0.19 11.3 0.0 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 ATP-synt_E PF05680.12 EMG48010.1 - 0.45 10.9 2.6 1.2 9.5 2.6 1.7 1 0 0 1 1 1 0 ATP synthase E chain DNA_pol_phi PF04931.13 EMG48010.1 - 3.9 5.5 14.0 6.2 4.8 14.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Per1 PF04080.13 EMG48011.1 - 2e-89 299.7 19.1 2.7e-89 299.3 19.1 1.1 1 0 0 1 1 1 1 Per1-like family MFS_1 PF07690.16 EMG48012.1 - 0.0001 21.4 33.8 0.00024 20.1 32.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Cyclin_N PF00134.23 EMG48013.1 - 2.4e-11 43.5 0.4 4.9e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain ADH_N PF08240.12 EMG48015.1 - 2.1e-30 104.8 0.8 3.6e-30 104.0 0.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMG48015.1 - 7.3e-22 77.7 0.1 5.3e-21 74.9 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EMG48015.1 - 9.1e-05 22.3 0.0 9.1e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 EMG48015.1 - 0.00017 21.1 0.0 0.0003 20.4 0.0 1.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMG48015.1 - 0.0002 22.4 0.0 0.00039 21.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_16 PF10294.9 EMG48015.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase zf-CXXC PF02008.20 EMG48015.1 - 0.16 12.0 0.7 0.29 11.2 0.7 1.3 1 0 0 1 1 1 0 CXXC zinc finger domain TrkA_N PF02254.18 EMG48015.1 - 0.17 12.1 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.18 EMG48016.1 - 2.8e-19 69.2 1.3 2.8e-19 69.2 1.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG48016.1 - 6.9e-10 38.9 14.1 1.1e-09 38.2 14.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CTK3_C PF12350.8 EMG48016.1 - 0.032 14.4 0.4 0.092 12.9 0.4 1.7 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus AA_permease PF00324.21 EMG48017.1 - 1.1e-132 443.0 40.9 1.3e-132 442.8 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG48017.1 - 7e-34 117.4 45.6 9.2e-34 117.0 45.6 1.0 1 0 0 1 1 1 1 Amino acid permease Smim3 PF17307.2 EMG48017.1 - 0.2 11.1 0.0 0.2 11.1 0.0 2.7 3 0 0 3 3 3 0 Small integral membrane protein 3 JAB PF01398.21 EMG48018.1 - 2.4e-13 50.1 0.0 4.3e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EMG48018.1 - 0.0014 19.1 2.5 0.0028 18.1 2.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function HNF-1_N PF04814.13 EMG48018.1 - 0.069 13.8 0.2 0.7 10.5 0.1 2.1 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus LIP PF03583.14 EMG48018.1 - 0.092 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Say1_Mug180 PF10340.9 EMG48019.1 - 3.8e-30 105.0 0.1 5.5e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EMG48019.1 - 5.4e-13 49.3 0.0 9.1e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG48019.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 EMG48019.1 - 0.045 13.9 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain COesterase PF00135.28 EMG48019.1 - 0.1 11.5 0.0 0.5 9.2 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family ABC1 PF03109.16 EMG48020.1 - 3.1e-24 85.4 0.1 6.1e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 ABC1 family Utp13 PF08625.11 EMG48021.1 - 5.2e-46 156.1 0.2 8.5e-46 155.4 0.2 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 EMG48021.1 - 1.3e-40 136.6 17.6 1.9e-06 28.5 0.0 10.6 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG48021.1 - 3.4e-16 59.3 1.3 0.037 14.3 0.0 7.7 4 4 2 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EMG48021.1 - 0.00018 20.9 8.0 0.013 14.9 0.7 4.5 4 1 0 4 4 4 2 WD40-like domain eIF2A PF08662.11 EMG48021.1 - 0.0024 17.8 4.3 4.5 7.1 0.0 5.3 5 2 2 7 7 7 2 Eukaryotic translation initiation factor eIF2A CRF1 PF10380.9 EMG48022.1 - 4.4e-34 117.2 2.8 4.4e-34 117.2 2.8 3.5 3 2 0 3 3 3 1 Transcription factor CRF1 ATP-synt_E PF05680.12 EMG48022.1 - 1.1 9.6 7.1 1.3 9.4 0.5 3.8 3 0 0 3 3 3 0 ATP synthase E chain Ribonuclease_3 PF00636.26 EMG48023.1 - 1.4e-21 77.1 0.8 1.2e-20 74.0 0.0 2.8 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EMG48023.1 - 1.1e-18 67.7 3.4 1.8e-18 66.9 0.0 2.6 3 0 0 3 3 3 1 Ribonuclease-III-like dsrm PF00035.26 EMG48023.1 - 3.5e-15 56.5 0.2 1.3e-07 32.2 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif RNase_3_N PF18497.1 EMG48023.1 - 7.6e-06 26.1 0.3 2e-05 24.7 0.3 1.7 1 0 0 1 1 1 1 Ribonuclease III N-terminal domain AcetylCoA_hydro PF02550.15 EMG48025.1 - 1.9e-63 214.1 0.0 3.1e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EMG48025.1 - 5.8e-44 149.7 0.0 9.1e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 EMG48025.1 - 0.12 11.7 0.0 0.55 9.6 0.0 2.2 3 0 0 3 3 3 0 Coenzyme A transferase SSF PF00474.17 EMG48026.1 - 3.8e-06 26.0 32.7 1.6e-05 24.0 31.5 2.5 1 1 1 2 2 2 1 Sodium:solute symporter family Say1_Mug180 PF10340.9 EMG48027.1 - 6.2e-24 84.6 0.1 7.8e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EMG48027.1 - 1.2e-12 48.1 0.0 1.7e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG48027.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 EMG48028.1 - 1.6e-28 99.7 0.0 2.2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EMG48028.1 - 6.8e-13 49.0 0.0 1.3e-12 48.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG48028.1 - 0.034 13.4 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 EMG48028.1 - 0.21 10.4 0.0 0.88 8.4 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family NDK PF00334.19 EMG48030.1 - 4.5e-53 178.9 0.0 5.1e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase WD40 PF00400.32 EMG48031.1 - 3.4e-14 53.0 10.5 0.0038 18.0 0.2 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat RabGAP-TBC PF00566.18 EMG48032.1 - 8.1e-12 45.2 10.5 8.1e-12 45.2 10.5 3.0 3 1 0 3 3 3 2 Rab-GTPase-TBC domain DUF2018 PF09442.10 EMG48032.1 - 0.018 16.0 0.7 0.068 14.1 0.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) UPF0114 PF03350.16 EMG48032.1 - 0.24 11.6 2.4 0.33 11.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 Dopey_N PF04118.14 EMG48033.1 - 2.8e-108 361.6 1.0 2.8e-108 361.6 1.0 2.6 2 0 0 2 2 2 1 Dopey, N-terminal Barstar PF01337.18 EMG48033.1 - 0.0097 15.9 0.8 0.033 14.2 0.3 2.2 2 0 0 2 2 2 1 Barstar (barnase inhibitor) UbiA PF01040.18 EMG48034.1 - 5.2e-51 173.4 11.7 8.6e-51 172.7 11.7 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family EptA_B_N PF08019.12 EMG48034.1 - 2.1 8.2 6.0 0.29 11.0 0.2 2.4 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB MitMem_reg PF13012.6 EMG48035.1 - 4.9e-34 117.1 0.4 8.8e-34 116.3 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EMG48035.1 - 1e-29 102.9 0.0 1.9e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FUSC-like PF12805.7 EMG48035.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS ATP_bind_1 PF03029.17 EMG48036.1 - 5.6e-69 232.6 0.1 7.9e-69 232.1 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GP17 PF17420.2 EMG48036.1 - 0.023 14.8 0.7 0.054 13.7 0.7 1.6 1 0 0 1 1 1 0 Superinfection exclusion gene product 17 DUF3835 PF12927.7 EMG48037.1 - 1.3e-20 74.0 1.7 1.3e-20 74.0 1.7 6.9 6 4 2 8 8 8 2 Domain of unknown function (DUF3835) DUF365 PF04033.12 EMG48037.1 - 0.033 14.5 0.5 0.17 12.2 0.5 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) NPV_P10 PF05531.12 EMG48038.1 - 8.5e-05 22.9 4.5 0.001 19.5 0.5 2.2 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 EMG48038.1 - 0.0055 16.1 2.4 0.0085 15.5 2.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) MetOD2 PF18548.1 EMG48038.1 - 0.0067 16.5 5.3 0.15 12.2 0.5 3.0 2 1 0 2 2 2 1 Metanogen output domain 2 Baculo_PEP_C PF04513.12 EMG48038.1 - 0.009 16.1 1.7 0.15 12.1 0.5 2.1 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EMG48038.1 - 0.011 14.6 13.8 0.016 14.1 3.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Tropomyosin PF00261.20 EMG48038.1 - 0.012 14.9 14.8 0.036 13.4 2.5 3.1 3 0 0 3 3 3 0 Tropomyosin HrpB7 PF09486.10 EMG48038.1 - 0.014 15.8 1.9 0.12 12.7 1.9 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) COG2 PF06148.11 EMG48038.1 - 0.02 15.0 8.5 0.31 11.1 0.5 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Histone_HNS PF00816.21 EMG48038.1 - 0.02 15.7 6.1 0.26 12.1 1.5 2.7 1 1 2 3 3 3 0 H-NS histone family HIP1_clath_bdg PF16515.5 EMG48038.1 - 0.031 14.9 8.4 0.094 13.3 0.7 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 EMG48038.1 - 0.033 14.2 7.2 0.99 9.5 0.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EMG48038.1 - 0.05 13.9 7.7 0.24 11.7 0.8 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Apolipoprotein PF01442.18 EMG48038.1 - 0.065 13.1 8.8 0.49 10.2 8.8 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CENP-F_leu_zip PF10473.9 EMG48038.1 - 0.069 13.2 12.6 0.048 13.7 2.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4446 PF14584.6 EMG48038.1 - 0.19 11.7 5.5 0.64 10.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Phage_Mu_Gam PF07352.12 EMG48038.1 - 0.22 11.4 6.9 0.37 10.7 0.2 2.4 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF4795 PF16043.5 EMG48038.1 - 0.23 11.0 7.9 0.18 11.4 5.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) SlyX PF04102.12 EMG48038.1 - 0.24 12.0 5.1 3.8 8.2 0.4 2.9 2 1 2 4 4 4 0 SlyX HAUS6_N PF14661.6 EMG48038.1 - 0.25 10.9 7.0 0.19 11.3 1.3 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Fez1 PF06818.15 EMG48038.1 - 0.42 11.0 9.7 0.17 12.3 6.0 1.9 1 1 1 2 2 2 0 Fez1 BST2 PF16716.5 EMG48038.1 - 0.51 10.9 8.1 2.8 8.6 0.5 3.3 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 PI3K_P85_iSH2 PF16454.5 EMG48038.1 - 0.55 9.8 10.9 0.19 11.3 2.4 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tup_N PF08581.10 EMG48038.1 - 0.68 10.3 9.8 10 6.5 4.8 3.2 2 1 0 2 2 2 0 Tup N-terminal DUF5082 PF16888.5 EMG48038.1 - 0.74 10.1 9.4 1.9 8.8 1.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Atg14 PF10186.9 EMG48038.1 - 0.74 8.8 8.4 0.74 8.8 6.4 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 EMG48038.1 - 1.8 8.7 9.6 5.6 7.1 5.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GST_N PF02798.20 EMG48039.1 - 7e-14 51.9 0.0 1.7e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMG48039.1 - 2.3e-11 43.7 0.0 3.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMG48039.1 - 4.3e-11 43.1 0.0 7.1e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMG48039.1 - 4.1e-10 39.7 0.0 8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMG48039.1 - 1.8e-09 37.7 0.0 3.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMG48039.1 - 1.4e-05 25.1 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3427 PF11907.8 EMG48039.1 - 0.021 14.1 0.1 0.026 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) Pkinase PF00069.25 EMG48040.1 - 1.1e-70 238.0 0.0 1.1e-70 238.0 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG48040.1 - 3.4e-36 124.9 0.0 1.4e-35 122.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 EMG48040.1 - 1.4e-13 50.6 3.0 1.4e-13 50.6 3.0 2.2 2 0 0 2 2 2 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 EMG48040.1 - 0.00028 20.3 0.0 0.00089 18.7 0.0 1.9 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EMG48040.1 - 0.14 12.0 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family SNARE PF05739.19 EMG48040.1 - 8 6.5 8.2 2 8.5 0.7 2.7 2 0 0 2 2 2 0 SNARE domain Snf7 PF03357.21 EMG48041.1 - 1.3e-12 47.6 15.5 1.6e-12 47.4 15.5 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 EMG48041.1 - 0.026 14.4 7.0 0.046 13.6 7.0 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway FKBP_C PF00254.28 EMG48041.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase DUF948 PF06103.11 EMG48041.1 - 1.5 9.1 11.2 0.93 9.8 4.4 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3886 PF13025.6 EMG48041.1 - 2.6 8.3 9.3 0.78 10.0 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) DUF724 PF05266.14 EMG48041.1 - 8.2 6.2 9.5 7.6 6.3 6.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Hyphal_reg_CWP PF11765.8 EMG48043.1 - 1.2e-117 392.5 14.1 1.3e-117 392.4 14.1 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Herpes_UL36 PF03586.13 EMG48044.1 - 0.25 10.6 3.9 0.25 10.6 2.9 1.4 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein PhzC-PhzF PF02567.16 EMG48046.1 - 6.9e-68 229.2 0.0 7.7e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 EMG48046.1 - 5.4e-08 32.3 0.0 1.3e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Proline racemase DUF3818 PF12825.7 EMG48047.1 - 8.6e-91 304.5 16.7 9.9e-46 156.3 0.5 2.5 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EMG48047.1 - 2.5e-35 121.3 2.9 7.7e-35 119.7 2.9 1.9 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EMG48047.1 - 1.5e-08 34.6 2.2 1.5e-08 34.6 2.2 2.9 3 0 0 3 3 3 1 PX domain Alpha-amylase_C PF02806.18 EMG48048.1 - 8e-29 100.0 0.6 3.7e-28 97.8 0.1 2.5 3 0 0 3 3 3 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EMG48048.1 - 1.3e-15 57.5 0.1 3.6e-15 56.1 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EMG48048.1 - 3.1e-12 46.7 1.3 1.3e-10 41.4 0.4 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Sec1 PF00995.23 EMG48049.1 - 8.8e-60 203.5 2.9 1.1e-59 203.2 2.9 1.0 1 0 0 1 1 1 1 Sec1 family Syntaxin-18_N PF10496.9 EMG48049.1 - 0.033 14.5 1.2 0.07 13.4 1.2 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DUF3439 PF11921.8 EMG48050.1 - 0.026 14.5 1.0 0.037 14.0 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) B277 PF17623.2 EMG48050.1 - 1.3 8.0 3.1 1.9 7.5 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function Actin PF00022.19 EMG48051.1 - 7.8e-104 347.5 0.0 9.2e-104 347.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EMG48051.1 - 0.00097 18.0 0.0 0.11 11.3 0.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein KH_1 PF00013.29 EMG48052.1 - 1.6e-37 127.2 3.0 2.7e-15 55.9 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EMG48052.1 - 1e-12 47.7 1.9 0.004 17.0 0.0 3.9 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 EMG48052.1 - 2.7e-09 36.7 2.6 0.026 14.3 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EMG48052.1 - 5.1e-06 26.5 1.1 0.3 11.2 0.0 3.4 3 0 0 3 3 3 3 NusA-like KH domain Secretin_N_2 PF07655.13 EMG48053.1 - 0.0086 16.6 19.6 0.43 11.1 7.1 2.4 2 0 0 2 2 2 2 Secretin N-terminal domain Sec1 PF00995.23 EMG48054.1 - 4.9e-42 144.9 5.9 5.5e-42 144.8 5.9 1.0 1 0 0 1 1 1 1 Sec1 family Syntaxin-18_N PF10496.9 EMG48054.1 - 0.012 15.8 1.4 0.025 14.8 1.4 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus RNase_H PF00075.24 EMG48055.1 - 6.2e-27 94.5 9.5 1.2e-26 93.6 9.5 1.5 1 1 0 1 1 1 1 RNase H SF-assemblin PF06705.11 EMG48055.1 - 0.079 12.3 0.7 0.11 11.9 0.7 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin Cauli_VI PF01693.16 EMG48055.1 - 0.31 11.4 2.1 0.86 10.0 2.1 1.8 1 0 0 1 1 1 0 Caulimovirus viroplasmin PhzC-PhzF PF02567.16 EMG48056.1 - 2.3e-60 204.5 0.0 2.6e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 EMG48056.1 - 1.4e-08 34.1 0.0 2.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Proline racemase LRR_8 PF13855.6 EMG48058.1 - 8.7e-05 22.2 10.4 0.31 10.8 0.0 6.0 6 0 0 6 6 6 2 Leucine rich repeat LRR_4 PF12799.7 EMG48058.1 - 0.0033 17.8 26.2 0.36 11.3 0.0 10.2 8 3 2 10 10 10 1 Leucine Rich repeats (2 copies) F-box_4 PF15966.5 EMG48058.1 - 0.0076 16.1 0.2 0.064 13.1 0.1 2.7 3 0 0 3 3 3 1 F-box Gal11_ABD1 PF18535.1 EMG48058.1 - 0.075 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) Pyr_redox_2 PF07992.14 EMG48059.1 - 3.1e-15 56.2 0.0 3.7e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ATP_transf PF09830.9 EMG48060.1 - 4.5e-19 68.3 0.0 8.2e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 EMG48060.1 - 0.00012 21.9 0.1 0.00022 21.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) HIT PF01230.23 EMG48060.1 - 0.00015 22.4 0.0 0.00038 21.1 0.0 1.6 1 0 0 1 1 1 1 HIT domain DUF4931 PF16285.5 EMG48060.1 - 0.0023 17.3 0.2 0.0056 16.0 0.1 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4931) AMP-binding PF00501.28 EMG48062.1 - 5.9e-53 180.0 0.0 2.9e-30 105.2 0.0 3.7 2 2 0 2 2 2 2 AMP-binding enzyme PPR PF01535.20 EMG48063.1 - 2.8e-10 39.7 3.8 0.033 14.4 0.1 5.6 5 1 0 5 5 5 3 PPR repeat PPR_2 PF13041.6 EMG48063.1 - 2.2e-09 37.4 4.7 0.013 15.7 0.4 5.0 3 1 2 5 5 5 3 PPR repeat family PPR_long PF17177.4 EMG48063.1 - 1e-05 25.1 0.3 0.00091 18.6 0.0 2.5 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP Rapsyn_N PF10579.9 EMG48063.1 - 0.012 15.7 0.1 0.59 10.3 0.1 3.6 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region PPR_3 PF13812.6 EMG48063.1 - 0.015 15.3 5.6 0.045 13.8 0.2 3.8 3 2 2 5 5 5 0 Pentatricopeptide repeat domain ATP13 PF12921.7 EMG48063.1 - 0.052 13.4 0.4 1.3 8.9 0.3 2.6 1 1 1 2 2 2 0 Mitochondrial ATPase expression tRNA-synt_1 PF00133.22 EMG48064.1 - 3.9e-50 170.7 0.9 4.8e-17 61.4 0.4 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EMG48064.1 - 5e-44 150.0 0.0 1e-43 149.0 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EMG48064.1 - 6.3e-27 94.3 0.7 2.8e-21 75.7 0.0 5.0 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EMG48064.1 - 4.8e-12 46.1 1.5 6.5e-12 45.7 0.1 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EMG48064.1 - 0.035 13.5 0.0 0.67 9.2 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 EMG48064.1 - 0.15 10.9 0.2 18 4.1 0.1 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Zn-ribbon_8 PF09723.10 EMG48064.1 - 0.66 10.1 3.7 1.4 9.0 0.6 2.7 3 0 0 3 3 3 0 Zinc ribbon domain PYST-C1 PF09690.10 EMG48065.1 - 0.0037 17.0 6.9 0.009 15.7 3.3 3.3 2 0 0 2 2 2 1 Plasmodium yoelii subtelomeric region (PYST-C1) CRAL_TRIO PF00650.20 EMG48066.1 - 3.3e-41 140.6 0.1 8.2e-41 139.4 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMG48066.1 - 3.4e-08 33.5 0.0 9.8e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EMG48066.1 - 4.7e-08 33.3 0.0 8.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUSP PF06337.12 EMG48066.1 - 0.093 13.4 0.9 0.54 10.9 0.1 2.6 2 0 0 2 2 2 0 DUSP domain Mito_carr PF00153.27 EMG48067.1 - 4.2e-60 199.7 2.1 5.5e-20 71.1 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.16 EMG48068.1 - 4.2e-37 126.1 0.2 5e-37 125.9 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Pyr_redox_2 PF07992.14 EMG48069.1 - 1.2e-15 57.6 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EMG48070.1 - 1.1e-37 129.9 36.9 1.1e-37 129.9 36.9 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG48070.1 - 1.1e-14 54.1 9.9 1.1e-14 54.1 9.9 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter DUF2628 PF10947.8 EMG48070.1 - 1.7 9.0 7.1 1.3 9.4 1.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) Asp PF00026.23 EMG48071.1 - 1.1e-86 291.1 10.2 1.3e-86 290.9 10.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMG48071.1 - 1.5e-09 38.4 6.3 3.6e-09 37.1 4.9 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EMG48071.1 - 5.6e-07 30.0 1.1 0.2 12.2 0.2 4.6 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EMG48071.1 - 7e-06 26.6 3.5 0.83 10.3 0.9 4.4 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 EMG48071.1 - 0.0064 16.3 0.1 0.36 10.6 0.1 2.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Fungal_trans_2 PF11951.8 EMG48072.1 - 9.8e-34 116.8 1.4 1.2e-33 116.4 1.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG48072.1 - 4.5e-08 33.1 10.1 7.7e-08 32.3 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2456 PF10445.9 EMG48072.1 - 0.1 12.7 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) RL10P_insert PF17777.1 EMG48073.1 - 6.6e-20 70.9 0.0 1.2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EMG48073.1 - 7.8e-17 61.3 0.1 1.4e-16 60.5 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L10 Sipho_tail PF05709.11 EMG48073.1 - 0.021 14.3 0.0 0.17 11.3 0.0 2.0 1 1 1 2 2 2 0 Phage tail protein CRT10 PF08728.10 EMG48074.1 - 3.3e-127 425.6 12.5 1.5e-90 304.4 3.9 2.4 1 1 1 2 2 2 2 CRT10 WD40 PF00400.32 EMG48074.1 - 0.053 14.4 0.5 5.4 8.1 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat GAF_2 PF13185.6 EMG48075.1 - 1.3e-11 44.9 0.0 1.8e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EMG48075.1 - 1.6e-06 28.8 0.0 1.7e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EMG48075.1 - 0.0086 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 GAF domain PLDc_2 PF13091.6 EMG48076.1 - 0.034 14.0 0.5 0.034 14.0 0.5 1.6 2 0 0 2 2 2 0 PLD-like domain zf-C3HC4_5 PF17121.5 EMG48076.1 - 0.05 13.5 1.3 0.055 13.4 0.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PY_rept_46 PF09689.10 EMG48076.1 - 7.5 7.2 10.1 0.13 12.8 2.8 2.0 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) LicD PF04991.13 EMG48077.1 - 1.6e-22 80.8 7.3 3.3e-22 79.8 2.8 4.6 4 2 1 5 5 5 2 LicD family DUF4952 PF16310.5 EMG48077.1 - 0.17 12.1 0.1 0.4 10.9 0.1 1.5 1 0 0 1 1 1 0 Domian of unknown function (DUF4952) FapA PF03961.13 EMG48078.1 - 0.51 8.9 17.4 0.79 8.3 17.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rogdi_lz PF10259.9 EMG48079.1 - 1.7e-47 162.2 0.5 2e-47 161.9 0.5 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein TSLP PF15216.6 EMG48079.1 - 0.014 15.6 0.1 0.045 14.0 0.1 1.8 1 0 0 1 1 1 0 Thymic stromal lymphopoietin Peptidase_M16_M PF16187.5 EMG48080.1 - 4.9e-81 272.1 2.7 1.2e-80 270.8 2.7 1.7 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EMG48080.1 - 2.1e-43 147.9 1.6 1.2e-42 145.4 0.2 2.8 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMG48080.1 - 1.9e-33 116.1 0.3 3.3e-21 76.1 0.1 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain WYL_3 PF18488.1 EMG48080.1 - 0.15 12.4 0.5 0.48 10.8 0.5 1.9 1 0 0 1 1 1 0 WYL domain ArAE_1_C PF11728.8 EMG48080.1 - 0.18 11.8 7.1 0.77 9.7 1.2 2.9 1 1 1 2 2 2 0 Putative aromatic acid exporter C-terminal domain FTHFS PF01268.19 EMG48081.1 - 9.6e-257 852.6 0.1 1.2e-256 852.3 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EMG48081.1 - 1.6e-63 212.8 0.5 4.2e-63 211.4 0.1 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EMG48081.1 - 5.9e-37 126.5 1.4 1.2e-36 125.5 1.4 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 2_5_RNA_ligase2 PF13563.6 EMG48081.1 - 0.0047 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Helicase_C_4 PF13871.6 EMG48081.1 - 0.053 13.2 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue GTP_EFTU PF00009.27 EMG48081.1 - 0.11 12.0 0.3 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain CbiA PF01656.23 EMG48081.1 - 0.14 12.2 0.1 0.87 9.7 0.1 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ADH_N PF08240.12 EMG48082.1 - 2.4e-23 82.1 0.7 3.9e-23 81.4 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMG48082.1 - 1.9e-18 66.7 0.0 3.6e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EMG48082.1 - 1.4e-08 34.3 0.0 2.4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EMG48082.1 - 5.8e-05 24.2 0.0 0.00015 22.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMG48082.1 - 0.00039 19.8 0.0 0.00063 19.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 EMG48082.1 - 0.0029 17.3 0.4 0.0063 16.3 0.3 1.6 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_2 PF03446.15 EMG48082.1 - 0.016 15.4 0.0 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-C2H2_11 PF16622.5 EMG48082.1 - 1.1 9.1 5.8 17 5.3 0.1 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type RNase_H PF00075.24 EMG48083.1 - 1.2e-28 100.0 0.3 2.3e-28 99.2 0.3 1.5 1 1 0 1 1 1 1 RNase H Cauli_VI PF01693.16 EMG48083.1 - 2.4e-14 53.3 3.8 2.4e-14 53.3 3.8 1.9 2 0 0 2 2 2 1 Caulimovirus viroplasmin BRCA2 PF00634.18 EMG48084.1 - 0.008 15.8 0.2 0.0099 15.5 0.2 1.2 1 0 0 1 1 1 1 BRCA2 repeat CH PF00307.31 EMG48085.1 - 8.5e-82 270.5 0.2 9.3e-21 74.1 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EMG48085.1 - 3e-09 36.6 0.1 0.16 11.8 0.0 4.4 4 0 0 4 4 4 4 CAMSAP CH domain EF-hand_7 PF13499.6 EMG48085.1 - 4.2e-05 23.9 1.9 7.2e-05 23.2 0.5 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EMG48085.1 - 0.00042 20.0 0.2 1.8 8.7 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain CH_2 PF06294.11 EMG48085.1 - 0.00053 20.1 0.2 4.7 7.4 0.0 4.1 4 0 0 4 4 4 1 CH-like domain in sperm protein EF-hand_1 PF00036.32 EMG48085.1 - 0.0045 16.4 0.3 0.39 10.4 0.0 3.1 3 0 0 3 3 3 1 EF hand PHD PF00628.29 EMG48086.1 - 5e-09 35.9 2.6 5e-09 35.9 2.6 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EMG48086.1 - 0.019 14.5 3.6 0.032 13.8 3.6 1.4 1 0 0 1 1 1 0 PHD-finger Androgen_recep PF02166.16 EMG48086.1 - 0.039 12.8 8.3 0.058 12.2 8.3 1.3 1 0 0 1 1 1 0 Androgen receptor DUF4587 PF15248.6 EMG48086.1 - 9.5 7.1 16.2 36 5.3 15.5 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4587) AltA1 PF16541.5 EMG48087.1 - 0.13 13.1 0.0 0.2 12.5 0.0 1.3 1 0 0 1 1 1 0 Alternaria alternata allergen 1 CPSase_L_D2 PF02786.17 EMG48088.1 - 1.1e-115 384.5 0.7 7.1e-83 277.3 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EMG48088.1 - 8.2e-49 164.7 0.0 1.8e-48 163.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 EMG48088.1 - 2.3e-48 164.0 0.0 4.7e-48 163.0 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 EMG48088.1 - 2e-45 154.9 0.0 4.9e-45 153.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 EMG48088.1 - 3.5e-39 133.9 0.0 8.7e-39 132.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EMG48088.1 - 6e-29 101.1 0.1 2.5e-28 99.1 0.1 2.1 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EMG48088.1 - 3.9e-20 71.8 0.0 2.9e-19 69.0 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EMG48088.1 - 8.4e-19 67.9 1.8 2.4e-10 40.3 0.1 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EMG48088.1 - 5e-16 58.7 0.1 2.7e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EMG48088.1 - 1.1e-10 41.4 0.0 1.5e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EMG48088.1 - 1.6e-06 28.3 0.7 0.013 15.6 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EMG48088.1 - 9.3e-06 25.5 0.1 0.0014 18.4 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EMG48088.1 - 0.00043 20.1 0.3 0.07 12.9 0.0 4.0 5 0 0 5 5 5 1 DJ-1/PfpI family GARS_A PF01071.19 EMG48088.1 - 0.0035 17.1 0.4 1.1 9.0 0.1 2.8 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.18 EMG48088.1 - 0.066 13.5 0.0 0.37 11.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain RRP36 PF06102.12 EMG48089.1 - 4.2e-46 156.9 26.7 4.2e-46 156.9 26.7 1.9 3 0 0 3 3 3 1 rRNA biogenesis protein RRP36 TBCC_N PF16752.5 EMG48089.1 - 0.022 15.2 7.9 0.022 15.2 7.9 3.5 2 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain PurK_C PF17769.1 EMG48089.1 - 0.057 13.1 0.3 1 9.1 0.1 2.5 2 0 0 2 2 2 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain DUF4758 PF15950.5 EMG48089.1 - 0.8 10.0 3.5 1.1 9.6 1.5 2.0 2 0 0 2 2 2 0 Putative sperm flagellar membrane protein Rhodanese PF00581.20 EMG48090.1 - 8.5e-16 58.4 0.0 1.3e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain ATP_bind_3 PF01171.20 EMG48091.1 - 2.4e-46 157.8 0.1 3.4e-46 157.3 0.1 1.2 1 0 0 1 1 1 1 PP-loop family QueC PF06508.13 EMG48091.1 - 0.0085 15.6 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 EMG48091.1 - 0.03 14.0 0.0 0.059 13.0 0.0 1.4 2 0 0 2 2 2 0 Asparagine synthase tRNA-synt_1 PF00133.22 EMG48092.1 - 1.6e-228 759.9 0.7 2.4e-228 759.3 0.3 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMG48092.1 - 2.3e-25 89.3 0.5 6.3e-25 87.9 0.2 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EMG48092.1 - 1.4e-15 57.0 0.9 2.5e-05 23.2 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EMG48092.1 - 0.006 16.0 0.0 0.02 14.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain PASTA PF03793.19 EMG48092.1 - 0.015 15.1 0.2 0.75 9.7 0.1 2.7 2 0 0 2 2 2 0 PASTA domain tRNA-synt_1_2 PF13603.6 EMG48092.1 - 0.095 12.2 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 WD40 PF00400.32 EMG48093.1 - 5.6e-20 71.3 21.0 0.0012 19.6 0.1 9.6 9 0 0 9 9 9 5 WD domain, G-beta repeat CPSF_A PF03178.15 EMG48093.1 - 0.064 12.6 3.8 0.15 11.4 0.0 3.1 3 1 1 4 4 4 0 CPSF A subunit region Beta_helix_2 PF18835.1 EMG48093.1 - 0.094 12.5 1.6 0.5 10.1 1.5 2.3 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase Aminotran_1_2 PF00155.21 EMG48094.1 - 7.7e-37 127.3 0.0 1.1e-36 126.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2 PF00096.26 EMG48095.1 - 3.4e-11 43.0 21.4 3.1e-06 27.3 1.7 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMG48095.1 - 1.4e-10 41.1 16.7 9.6e-08 32.1 2.6 4.8 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMG48095.1 - 4.1e-10 39.6 15.2 9.3e-05 23.0 1.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMG48095.1 - 2.5e-07 30.8 9.1 0.002 18.4 1.0 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EMG48095.1 - 9.1e-07 28.7 1.1 9.1e-07 28.7 1.1 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 EMG48095.1 - 0.0055 17.1 7.3 0.033 14.6 0.6 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EMG48095.1 - 0.041 13.7 2.9 1.9 8.3 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Zf_RING PF16744.5 EMG48095.1 - 0.071 13.2 4.6 0.65 10.1 0.9 3.0 1 1 2 3 3 3 0 KIAA1045 RING finger C1_4 PF07975.12 EMG48095.1 - 0.71 10.2 5.8 1.1 9.5 4.3 2.2 2 0 0 2 2 1 0 TFIIH C1-like domain C5HCH PF17982.1 EMG48095.1 - 1.2 9.4 6.3 0.15 12.2 1.8 1.9 2 0 0 2 2 2 0 NSD Cys-His rich domain DUF3333 PF11812.8 EMG48095.1 - 3 8.0 4.4 1.6 8.9 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3333) SUIM_assoc PF16619.5 EMG48096.1 - 0.025 14.6 3.7 0.052 13.6 3.7 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LRR_6 PF13516.6 EMG48096.1 - 0.091 12.9 10.1 9.5 6.6 0.0 5.7 5 0 0 5 5 5 0 Leucine Rich repeat F-box PF00646.33 EMG48096.1 - 0.48 10.4 3.3 1.6 8.7 0.4 3.0 2 1 0 2 2 2 0 F-box domain LRR_8 PF13855.6 EMG48096.1 - 0.58 10.0 14.7 0.13 12.1 1.4 4.6 4 1 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 EMG48096.1 - 0.96 10.0 29.3 0.1 13.1 4.4 6.2 5 1 2 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EMG48096.1 - 8 7.4 12.9 75 4.5 0.4 6.7 5 1 0 5 5 5 0 Leucine Rich Repeat DUF3074 PF11274.8 EMG48097.1 - 3.4e-20 72.8 0.0 7.5e-20 71.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) FAD_binding_3 PF01494.19 EMG48098.1 - 1.1e-78 265.0 0.0 1.1e-75 255.1 0.0 2.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EMG48098.1 - 1.4e-46 158.6 0.1 5.8e-46 156.6 0.0 2.0 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 EMG48098.1 - 0.0005 18.9 0.0 0.0023 16.7 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EMG48098.1 - 0.0069 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMG48098.1 - 0.0072 15.6 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMG48098.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EMG48098.1 - 0.02 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EMG48098.1 - 0.03 14.5 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMG48098.1 - 0.04 13.2 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMG48098.1 - 0.06 12.7 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF4990 PF16380.5 EMG48098.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DAO PF01266.24 EMG48098.1 - 0.087 12.4 0.0 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMG48098.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkH PF02386.16 EMG48099.1 - 3e-153 510.9 7.8 3e-153 510.9 7.8 2.0 2 0 0 2 2 2 1 Cation transport protein NOA36 PF06524.12 EMG48099.1 - 8.6 5.6 30.8 0.83 8.9 13.4 3.2 3 0 0 3 3 3 0 NOA36 protein Brix PF04427.18 EMG48100.1 - 1.5e-19 70.9 0.4 1.9e-19 70.5 0.4 1.1 1 0 0 1 1 1 1 Brix domain NAD_binding_6 PF08030.12 EMG48101.1 - 1.1e-26 93.8 0.1 1.7e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMG48101.1 - 1.9e-26 92.3 0.1 4.3e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EMG48101.1 - 6.3e-24 84.5 13.7 6.3e-24 84.5 13.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF4405 PF14358.6 EMG48101.1 - 8.8 7.0 21.5 5.8 7.5 2.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Peptidase_S64 PF08192.11 EMG48102.1 - 6.5e-272 904.1 21.6 1.1e-271 903.4 21.6 1.3 1 1 0 1 1 1 1 Peptidase family S64 MFS_1 PF07690.16 EMG48103.1 - 5.1e-37 127.6 36.6 5.1e-37 127.6 36.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_8 PF13855.6 EMG48104.1 - 0.0012 18.6 0.3 0.0033 17.1 0.3 1.8 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EMG48104.1 - 0.011 16.2 0.5 0.064 13.7 0.1 2.3 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EMG48104.1 - 0.039 14.5 0.3 0.41 11.4 0.1 2.5 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 EMG48104.1 - 0.051 13.6 0.6 0.34 11.1 0.2 2.2 2 0 0 2 2 2 0 Leucine Rich repeat DUF3969 PF13108.6 EMG48105.1 - 0.031 14.3 0.6 9.8 6.2 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3969) EOS1 PF12326.8 EMG48106.1 - 3.7e-14 53.0 2.3 3.7e-14 53.0 2.3 1.6 2 0 0 2 2 2 1 N-glycosylation protein RIBIOP_C PF04950.12 EMG48107.1 - 5.7e-102 341.1 0.0 8.8e-102 340.4 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EMG48107.1 - 8.6e-19 67.4 0.2 5.7e-18 64.8 0.2 2.3 1 1 0 1 1 1 1 AARP2CN (NUC121) domain PGA_cap PF09587.10 EMG48107.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Flocculin_t3 PF13928.6 EMG48108.1 - 0.022 15.3 12.9 0.022 15.3 12.9 11.4 5 4 2 7 7 7 0 Flocculin type 3 repeat DUF2892 PF11127.8 EMG48108.1 - 2.9 8.0 9.6 54 3.9 0.1 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2892) Tropomyosin_1 PF12718.7 EMG48109.1 - 8.3e-51 171.9 42.4 1e-50 171.6 42.4 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EMG48109.1 - 3.2e-06 26.7 40.4 0.00096 18.6 18.5 2.0 1 1 1 2 2 2 2 Tropomyosin ATG16 PF08614.11 EMG48109.1 - 4.6e-05 23.7 38.6 0.017 15.3 20.2 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) GAS PF13851.6 EMG48109.1 - 4.9e-05 22.8 40.1 6.4e-05 22.4 40.1 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EMG48109.1 - 8.9e-05 22.5 24.7 0.021 14.8 10.9 2.1 1 1 1 2 2 2 2 Laminin Domain II CENP-F_leu_zip PF10473.9 EMG48109.1 - 0.0002 21.4 11.7 0.0002 21.4 11.7 2.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 EMG48109.1 - 0.0011 18.9 18.1 0.0011 18.9 18.1 3.3 1 1 4 5 5 5 1 TATA element modulatory factor 1 DNA binding Filament PF00038.21 EMG48109.1 - 0.0017 18.0 33.3 0.0049 16.5 21.9 2.0 1 1 1 2 2 2 1 Intermediate filament protein DUF3450 PF11932.8 EMG48109.1 - 0.0018 17.7 32.2 0.024 14.0 11.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) Taxilin PF09728.9 EMG48109.1 - 0.0021 17.3 12.1 0.0021 17.3 12.1 2.3 1 1 1 2 2 2 1 Myosin-like coiled-coil protein Uso1_p115_C PF04871.13 EMG48109.1 - 0.004 17.5 41.8 0.1 13.0 19.8 2.0 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region TelA PF05816.11 EMG48109.1 - 0.0043 16.2 6.2 0.0043 16.2 6.2 2.1 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) DUF724 PF05266.14 EMG48109.1 - 0.0058 16.5 33.4 0.029 14.2 15.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF724) KELK PF15796.5 EMG48109.1 - 0.0071 16.8 4.9 0.0071 16.8 4.9 4.0 1 1 3 4 4 4 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Nup54 PF13874.6 EMG48109.1 - 0.0072 16.4 23.8 0.055 13.6 12.7 2.1 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 XhlA PF10779.9 EMG48109.1 - 0.012 15.8 3.9 0.012 15.8 3.9 4.3 2 2 2 4 4 4 0 Haemolysin XhlA FliD_C PF07195.12 EMG48109.1 - 0.018 14.4 23.6 0.38 10.1 14.8 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus KLRAQ PF10205.9 EMG48109.1 - 0.019 15.2 30.6 0.3 11.4 11.2 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein APG6_N PF17675.1 EMG48109.1 - 0.019 15.5 49.5 1 9.9 27.8 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 EMG48109.1 - 0.029 14.6 39.2 0.037 14.2 29.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Rho_Binding PF08912.11 EMG48109.1 - 0.038 14.8 4.5 0.038 14.8 4.5 4.1 1 1 3 4 4 4 0 Rho Binding bZIP_1 PF00170.21 EMG48109.1 - 0.04 14.0 39.5 0.083 13.0 3.4 5.2 1 1 3 4 4 4 0 bZIP transcription factor Spc7 PF08317.11 EMG48109.1 - 0.064 12.1 40.0 0.055 12.4 27.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 EMG48109.1 - 0.071 13.6 33.6 0.1 13.0 30.7 1.9 1 1 1 2 2 2 0 Fez1 Prefoldin PF02996.17 EMG48109.1 - 0.086 12.8 35.7 0.12 12.3 2.9 4.0 1 1 2 4 4 4 0 Prefoldin subunit FapA PF03961.13 EMG48109.1 - 0.09 11.4 33.3 0.22 10.1 16.2 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 EMG48109.1 - 0.091 12.8 21.3 0.33 11.0 6.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ZapB PF06005.12 EMG48109.1 - 0.098 13.1 48.0 2.8 8.5 5.5 4.1 2 1 1 3 3 2 0 Cell division protein ZapB DUF4201 PF13870.6 EMG48109.1 - 0.1 12.3 34.3 0.19 11.5 11.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4795 PF16043.5 EMG48109.1 - 0.1 12.2 34.2 2 8.0 21.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) NPV_P10 PF05531.12 EMG48109.1 - 0.12 12.8 17.5 0.21 12.1 0.5 3.7 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein MIS13 PF08202.11 EMG48109.1 - 0.13 11.6 33.0 3.1 7.0 13.4 2.2 1 1 1 2 2 2 0 Mis12-Mtw1 protein family Prefoldin_2 PF01920.20 EMG48109.1 - 0.13 12.3 42.4 0.24 11.4 29.9 3.4 1 1 1 2 2 2 0 Prefoldin subunit WXG100 PF06013.12 EMG48109.1 - 0.16 12.2 16.8 2.5 8.4 0.5 3.7 2 1 1 3 3 3 0 Proteins of 100 residues with WXG FlaC_arch PF05377.11 EMG48109.1 - 0.19 12.2 32.3 0.39 11.1 5.6 5.0 1 1 4 5 5 4 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 EMG48109.1 - 0.21 11.4 40.7 2.1 8.1 28.6 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ERM PF00769.19 EMG48109.1 - 0.21 11.3 41.4 1.4 8.7 26.9 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.8 EMG48109.1 - 0.22 11.6 37.1 0.88 9.6 12.6 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-K PF11802.8 EMG48109.1 - 0.22 11.0 31.5 1.1 8.8 31.5 1.9 1 1 0 1 1 1 0 Centromere-associated protein K DHR10 PF18595.1 EMG48109.1 - 0.25 11.4 40.2 0.14 12.2 15.6 2.7 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain LPP PF04728.13 EMG48109.1 - 0.25 11.7 14.3 0.72 10.3 0.9 4.1 3 2 0 4 4 3 0 Lipoprotein leucine-zipper PspA_IM30 PF04012.12 EMG48109.1 - 0.28 10.8 30.2 0.04 13.5 10.0 2.8 1 1 1 2 2 2 0 PspA/IM30 family CEP63 PF17045.5 EMG48109.1 - 0.3 11.0 32.0 0.47 10.3 10.1 2.0 1 1 0 2 2 2 0 Centrosomal protein of 63 kDa EzrA PF06160.12 EMG48109.1 - 0.34 9.0 36.6 5.6 5.0 36.6 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 EMG48109.1 - 0.34 11.0 44.3 0.41 10.7 23.4 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4472 PF14739.6 EMG48109.1 - 0.35 11.6 31.6 1.5 9.6 9.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) DUF16 PF01519.16 EMG48109.1 - 0.42 11.1 29.3 3.2 8.3 11.2 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ax_dynein_light PF10211.9 EMG48109.1 - 0.42 10.5 40.7 0.65 9.9 11.2 3.3 1 1 2 3 3 3 0 Axonemal dynein light chain DUF4200 PF13863.6 EMG48109.1 - 0.51 10.7 42.0 3.4 8.1 21.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) PI3K_P85_iSH2 PF16454.5 EMG48109.1 - 0.57 9.8 33.6 1.5 8.4 3.1 2.8 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BLOC1_2 PF10046.9 EMG48109.1 - 0.58 10.5 31.6 24 5.3 10.3 3.9 1 1 1 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc24 PF08286.11 EMG48109.1 - 0.65 10.3 38.1 2.1 8.6 5.4 4.0 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.6 EMG48109.1 - 0.7 10.4 26.7 1.1 9.7 7.8 3.5 1 1 2 3 3 3 0 Snapin/Pallidin MscS_porin PF12795.7 EMG48109.1 - 0.78 9.2 35.3 1.7 8.2 26.9 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain bZIP_2 PF07716.15 EMG48109.1 - 0.84 9.8 36.2 0.41 10.8 3.1 5.0 2 2 2 5 5 5 0 Basic region leucine zipper SlyX PF04102.12 EMG48109.1 - 0.91 10.2 25.2 0.35 11.5 7.8 3.7 1 1 3 4 4 4 0 SlyX TMPIT PF07851.13 EMG48109.1 - 1.1 8.4 29.6 0.5 9.6 14.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF745 PF05335.13 EMG48109.1 - 1.1 8.9 24.1 1 9.0 8.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) JIP_LZII PF16471.5 EMG48109.1 - 1.2 9.4 35.9 0.55 10.4 2.8 4.2 2 1 3 5 5 5 0 JNK-interacting protein leucine zipper II Lebercilin PF15619.6 EMG48109.1 - 1.2 8.7 40.4 10 5.7 24.7 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2937 PF11157.8 EMG48109.1 - 1.3 8.7 8.3 1.3 8.7 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Leu_zip PF15294.6 EMG48109.1 - 1.4 8.4 31.3 2.1 7.8 31.3 1.4 1 0 0 1 1 1 0 Leucine zipper T2SSM PF04612.12 EMG48109.1 - 1.4 8.9 10.4 0.41 10.7 2.6 2.7 1 1 2 3 3 2 0 Type II secretion system (T2SS), protein M DUF3584 PF12128.8 EMG48109.1 - 1.4 6.3 33.2 3.8 4.9 33.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.22 EMG48109.1 - 1.5 9.1 35.8 2.5 8.4 13.6 2.9 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Uds1 PF15456.6 EMG48109.1 - 1.5 9.0 28.8 0.057 13.6 18.1 2.7 1 1 2 3 3 3 0 Up-regulated During Septation Sec20 PF03908.13 EMG48109.1 - 1.6 8.7 13.6 0.42 10.5 6.3 2.8 1 1 2 3 3 3 0 Sec20 SOGA PF11365.8 EMG48109.1 - 1.8 9.8 26.2 0.65 11.2 16.1 3.0 2 1 1 3 3 2 0 Protein SOGA HMMR_N PF15905.5 EMG48109.1 - 1.8 8.0 42.5 1.6 8.1 34.3 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CALCOCO1 PF07888.11 EMG48109.1 - 1.8 7.3 35.6 1.2 7.9 14.0 1.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like KxDL PF10241.9 EMG48109.1 - 1.8 8.9 23.1 0.43 10.9 0.8 3.7 1 1 2 3 3 3 0 Uncharacterized conserved protein Atg14 PF10186.9 EMG48109.1 - 1.8 7.5 31.8 1.1 8.2 11.0 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MAD PF05557.13 EMG48109.1 - 2 6.7 37.2 2.6 6.3 37.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Fib_alpha PF08702.10 EMG48109.1 - 2.1 8.6 25.1 4.5 7.5 16.5 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 EMG48109.1 - 2.1 6.9 33.3 7.2 5.1 33.3 1.7 1 1 0 1 1 1 0 AAA domain HOOK PF05622.12 EMG48109.1 - 2.3 6.3 36.6 4.7 5.2 36.6 1.4 1 1 0 1 1 1 0 HOOK protein MbeD_MobD PF04899.12 EMG48109.1 - 2.4 8.3 11.9 6.8 6.9 1.5 3.0 2 1 1 3 3 3 0 MbeD/MobD like Rootletin PF15035.6 EMG48109.1 - 2.5 8.1 35.4 11 6.0 17.1 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Phage_GPO PF05929.11 EMG48109.1 - 2.5 7.7 25.4 0.56 9.8 15.5 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Med10 PF09748.9 EMG48109.1 - 2.5 8.1 11.8 4.6e+02 0.8 11.8 2.9 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Occludin_ELL PF07303.13 EMG48109.1 - 2.6 8.8 23.9 17 6.2 8.3 3.2 1 1 2 3 3 3 0 Occludin homology domain SHE3 PF17078.5 EMG48109.1 - 2.7 7.6 34.4 1.1 9.0 5.7 3.0 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 HisKA_3 PF07730.13 EMG48109.1 - 2.9 8.5 11.5 9.4 6.8 0.3 3.9 1 1 3 4 4 4 0 Histidine kinase HAUS-augmin3 PF14932.6 EMG48109.1 - 3.2 7.2 34.8 0.25 10.9 26.3 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 BRE1 PF08647.11 EMG48109.1 - 3.5 7.8 41.1 0.76 9.9 13.9 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase HAUS6_N PF14661.6 EMG48109.1 - 3.6 7.1 27.3 65 3.0 12.8 2.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4407 PF14362.6 EMG48109.1 - 3.7 6.8 25.5 6.6 6.0 25.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CLZ PF16526.5 EMG48109.1 - 4.3 7.8 32.9 16 5.9 4.3 4.1 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mod_r PF07200.13 EMG48109.1 - 4.3 7.4 38.7 12 5.9 12.8 3.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ABC_tran_CTD PF16326.5 EMG48109.1 - 4.5 7.6 42.1 0.18 12.1 9.6 3.7 1 1 3 4 4 4 0 ABC transporter C-terminal domain IFT57 PF10498.9 EMG48109.1 - 4.6 6.1 31.5 11 4.8 23.1 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF948 PF06103.11 EMG48109.1 - 4.6 7.6 17.7 1.8e+04 -5.4 17.7 3.1 1 1 0 1 1 0 0 Bacterial protein of unknown function (DUF948) Lectin_N PF03954.14 EMG48109.1 - 5 6.9 19.3 4.5 7.0 7.0 3.1 1 1 3 4 4 4 0 Hepatic lectin, N-terminal domain IZUMO PF15005.6 EMG48109.1 - 5 7.6 18.0 2 8.9 11.9 2.2 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF3287 PF11690.8 EMG48109.1 - 5 6.8 10.0 2.6 7.8 1.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) kleA_kleC PF17383.2 EMG48109.1 - 6.4 7.2 13.1 2 8.8 2.0 3.0 2 2 1 3 3 3 0 Uncharacterized KorC regulated protein A DUF4890 PF16231.5 EMG48109.1 - 6.5 7.3 21.2 0.14 12.6 10.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4890) DUF2203 PF09969.9 EMG48109.1 - 6.7 7.4 24.3 1.9 9.2 7.2 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) YabA PF06156.13 EMG48109.1 - 7.4 7.3 30.2 27 5.5 14.3 2.8 1 1 1 2 2 2 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 EMG48109.1 - 7.6 6.0 21.9 17 4.8 21.9 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF812 PF05667.11 EMG48109.1 - 7.6 5.3 37.8 81 1.9 37.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Mago_nashi PF02792.14 EMG48109.1 - 7.6 6.6 11.0 12 6.0 9.9 2.0 1 1 0 1 1 1 0 Mago nashi protein Sec34 PF04136.15 EMG48109.1 - 7.7 6.4 25.5 2 8.3 9.9 2.2 1 1 1 2 2 2 0 Sec34-like family EF1_GNE PF00736.19 EMG48109.1 - 8.1 6.7 15.4 14 6.0 1.0 3.3 1 1 2 3 3 3 0 EF-1 guanine nucleotide exchange domain Herpes_UL6 PF01763.16 EMG48109.1 - 8.9 4.7 22.2 39 2.6 20.1 2.2 1 1 1 2 2 2 0 Herpesvirus UL6 like LprI PF07007.12 EMG48109.1 - 9.6 6.9 16.7 2.1 9.0 7.8 3.2 1 1 1 2 2 2 0 Lysozyme inhibitor LprI Myb_DNA-bind_3 PF12776.7 EMG48111.1 - 0.00086 20.2 0.2 0.00086 20.2 0.2 3.1 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Pex14_N PF04695.13 EMG48111.1 - 0.013 16.1 11.8 0.013 16.1 11.8 3.3 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1387 PF07139.11 EMG48111.1 - 0.49 10.1 34.1 0.033 13.9 13.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) PRIMA1 PF16101.5 EMG48111.1 - 1.8 8.6 7.4 3.7 7.6 7.4 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ribosomal_S13 PF00416.22 EMG48112.1 - 3.6e-19 69.4 0.4 1.6e-11 44.7 0.7 2.0 1 1 1 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 EMG48112.1 - 0.018 13.9 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DNA_pol_lambd_f PF10391.9 EMG48112.1 - 0.094 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda zf-C2H2_2 PF12756.7 EMG48113.1 - 1.4e-33 115.2 6.8 1e-30 106.1 1.1 2.8 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 EMG48113.1 - 0.0025 18.2 2.4 5 7.7 0.0 4.0 3 0 0 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 EMG48113.1 - 0.021 15.1 0.2 0.021 15.1 0.2 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 EMG48113.1 - 0.03 12.9 0.1 0.03 12.9 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF629) DnaJ_C PF01556.18 EMG48114.1 - 2.4e-26 92.6 0.0 1.5e-25 90.0 0.0 2.0 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMG48114.1 - 1.2e-21 76.6 0.9 2.2e-21 75.7 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EMG48114.1 - 1.1e-09 38.5 10.8 2.2e-09 37.5 10.8 1.5 1 0 0 1 1 1 1 DnaJ central domain RseC_MucC PF04246.12 EMG48114.1 - 0.2 11.6 1.2 0.73 9.8 0.0 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Anti-TRAP PF15777.5 EMG48114.1 - 7.6 6.6 9.5 0.85 9.6 1.4 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Vac14_Fig4_bd PF11916.8 EMG48115.1 - 3e-68 229.0 13.3 6.6e-68 227.9 13.3 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EMG48115.1 - 5.2e-37 126.3 1.3 2.5e-35 120.9 0.5 3.0 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EMG48115.1 - 0.002 18.3 0.1 0.14 12.4 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 EMG48115.1 - 0.012 15.7 0.1 0.012 15.7 0.1 4.5 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EMG48115.1 - 0.024 15.1 0.0 0.78 10.3 0.0 3.1 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 EMG48115.1 - 0.067 13.6 0.0 2.8 8.4 0.0 3.9 3 1 2 5 5 5 0 HEAT repeats BUD22 PF09073.10 EMG48115.1 - 0.33 10.2 15.8 0.54 9.5 15.8 1.2 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 EMG48115.1 - 0.67 9.0 20.6 1.1 8.3 20.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AAA_11 PF13086.6 EMG48116.1 - 0.0021 17.9 0.5 0.0045 16.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain FidL_like PF15941.5 EMG48116.1 - 0.05 14.1 0.9 0.05 14.1 0.9 2.1 2 0 0 2 2 2 0 FidL-like putative membrane protein AAA_12 PF13087.6 EMG48117.1 - 3.1e-18 66.1 0.0 3.8e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMG48117.1 - 0.053 13.3 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain GSH_synth_ATP PF03917.17 EMG48118.1 - 1.1e-132 442.4 0.1 1.2e-132 442.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EMG48118.1 - 2.3e-33 114.7 0.1 5.6e-33 113.5 0.1 1.7 1 0 0 1 1 1 1 Eukaryotic glutathione synthase EI24 PF07264.11 EMG48119.1 - 5.6e-09 36.5 11.8 8.1e-09 36.0 11.8 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FUSC-like PF12805.7 EMG48119.1 - 0.52 9.4 6.1 0.88 8.6 6.1 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS SIL1 PF16782.5 EMG48120.1 - 1.3e-34 119.7 1.0 1.5e-34 119.6 1.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Cys_Met_Meta_PP PF01053.20 EMG48121.1 - 5.5e-141 469.5 0.0 6.2e-141 469.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMG48121.1 - 0.00014 21.2 0.1 0.0002 20.7 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMG48121.1 - 0.0023 17.3 0.1 0.01 15.2 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family WD40 PF00400.32 EMG48122.1 - 1.3e-05 25.8 4.9 0.017 16.0 0.4 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF2415 PF10313.9 EMG48122.1 - 0.00017 21.5 0.0 0.28 11.1 0.0 3.8 4 0 0 4 4 4 2 Uncharacterised protein domain (DUF2415) TauD PF02668.16 EMG48123.1 - 5.7e-54 183.7 0.0 6.9e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RCC1 PF00415.18 EMG48124.1 - 2.5e-32 111.3 15.0 6e-08 33.2 0.1 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMG48124.1 - 1.9e-18 65.7 27.2 5.2e-11 42.1 0.3 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat DUF775 PF05603.12 EMG48125.1 - 2.3e-64 216.6 0.1 2.7e-64 216.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Kre28 PF17097.5 EMG48126.1 - 1.9e-06 27.1 19.4 2.4e-06 26.7 19.4 1.0 1 0 0 1 1 1 1 Spindle pole body component Csm2_III-A PF03750.13 EMG48126.1 - 0.0068 17.2 0.2 0.0068 17.2 0.2 2.4 2 1 0 2 2 2 1 Csm2 Type III-A DUF4407 PF14362.6 EMG48126.1 - 0.032 13.6 10.0 0.026 13.9 9.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1843 PF08898.10 EMG48126.1 - 0.038 14.5 0.9 0.038 14.5 0.9 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF1843) ZapB PF06005.12 EMG48126.1 - 0.041 14.3 2.3 0.041 14.3 2.3 3.3 1 1 1 2 2 1 0 Cell division protein ZapB SpoU_sub_bind PF08032.12 EMG48126.1 - 0.16 12.3 2.5 9.8 6.5 0.1 2.9 3 1 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding UPF0242 PF06785.11 EMG48126.1 - 1.1 9.4 19.9 1.4 9.0 19.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CSN5_C PF18323.1 EMG48126.1 - 3.1 8.8 8.9 3.6 8.6 1.2 3.1 1 1 3 4 4 4 0 Cop9 signalosome subunit 5 C-terminal domain Pup PF05639.11 EMG48126.1 - 3.8 8.5 9.2 1.4 9.9 4.8 2.5 1 1 2 3 3 3 0 Pup-like protein DUF948 PF06103.11 EMG48126.1 - 4 7.8 11.0 0.3 11.4 4.9 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BST2 PF16716.5 EMG48126.1 - 6.1 7.5 18.1 0.11 13.1 8.3 2.5 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 PP2C PF00481.21 EMG48127.1 - 6e-43 147.3 0.0 1.7e-42 145.8 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EMG48127.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C MFS_1 PF07690.16 EMG48128.1 - 2.6e-18 66.1 25.8 3.6e-18 65.6 25.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 EMG48128.1 - 0.042 11.8 0.0 0.075 10.9 0.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GRDP-like PF07173.12 EMG48129.1 - 2.4e-21 76.9 1.2 6.3e-20 72.3 0.2 3.2 3 0 0 3 3 3 1 Glycine-rich domain-containing protein-like ABC_membrane PF00664.23 EMG48130.1 - 2.6e-52 178.2 48.3 5.8e-32 111.4 22.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMG48130.1 - 2.5e-50 170.6 0.4 1e-30 107.0 0.0 3.4 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMG48130.1 - 6.4e-09 36.0 6.7 0.34 10.7 0.0 5.4 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMG48130.1 - 4.7e-07 29.5 7.0 0.0033 16.9 0.5 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMG48130.1 - 8.9e-07 28.6 1.4 0.002 17.9 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EMG48130.1 - 2.5e-05 24.3 0.5 0.22 11.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMG48130.1 - 7.9e-05 22.6 1.9 0.05 13.5 0.2 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EMG48130.1 - 0.0012 19.2 0.5 0.2 12.0 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.17 EMG48130.1 - 0.0054 16.5 0.6 8.9 6.0 0.0 3.5 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein T2SSE PF00437.20 EMG48130.1 - 0.0073 15.4 0.0 0.048 12.7 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 EMG48130.1 - 0.012 15.3 0.6 4 7.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EMG48130.1 - 0.019 15.0 0.5 0.019 15.0 0.5 4.2 5 0 0 5 5 5 0 Dynamin family ATP-synt_ab PF00006.25 EMG48130.1 - 0.061 13.0 0.2 0.69 9.5 0.1 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 EMG48130.1 - 0.062 12.3 0.6 1 8.3 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EMG48130.1 - 0.073 13.4 2.6 9.7 6.5 0.2 3.2 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EMG48130.1 - 0.08 13.5 5.6 3.1 8.3 0.0 3.2 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 EMG48130.1 - 0.086 12.1 0.3 7.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EMG48130.1 - 0.1 11.9 1.1 4.4 6.6 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 EMG48130.1 - 0.2 11.3 0.9 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EMG48130.1 - 1.1 9.2 9.8 2.4 8.2 0.2 2.9 2 0 0 2 2 2 0 Helicase HerA, central domain UQ_con PF00179.26 EMG48131.1 - 3.3e-43 146.7 0.1 3.8e-43 146.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMG48131.1 - 4e-06 26.6 0.0 4.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EMG48131.1 - 0.053 13.4 0.6 0.11 12.4 0.6 1.5 1 1 0 1 1 1 0 UEV domain His_Phos_1 PF00300.22 EMG48132.1 - 2.1e-35 122.2 0.0 2.7e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 EMG48132.1 - 5.2e-12 45.6 1.9 0.00095 18.5 0.1 3.2 2 1 1 3 3 3 3 6-phosphofructo-2-kinase hSac2 PF12456.8 EMG48132.1 - 0.033 13.9 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Inositol phosphatase cNMP_binding PF00027.29 EMG48133.1 - 3.1e-24 84.9 0.3 1.5e-14 53.8 0.0 4.9 5 0 0 5 5 5 2 Cyclic nucleotide-binding domain Patatin PF01734.22 EMG48133.1 - 2.8e-20 73.4 2.1 9.1e-19 68.4 2.1 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase Pex19 PF04614.12 EMG48134.1 - 6.6e-67 225.8 14.2 6.6e-67 225.8 14.2 1.6 1 1 1 2 2 2 1 Pex19 protein family ApoLp-III PF07464.11 EMG48134.1 - 0.032 14.3 14.7 0.034 14.2 6.0 3.0 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF349 PF03993.12 EMG48134.1 - 0.086 13.1 7.2 0.28 11.5 0.3 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF3597 PF12200.8 EMG48134.1 - 0.7 10.4 5.7 19 5.8 5.7 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3597) Turandot PF07240.11 EMG48134.1 - 1.3 9.0 5.5 4.5 7.3 0.3 3.3 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot FapA PF03961.13 EMG48134.1 - 1.5 7.3 9.9 1.1 7.7 1.2 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A FliE PF02049.18 EMG48134.1 - 10 6.4 8.2 17 5.6 0.3 3.4 2 1 2 4 4 4 0 Flagellar hook-basal body complex protein FliE AAA PF00004.29 EMG48135.1 - 4e-88 292.6 0.0 2.5e-42 144.4 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMG48135.1 - 3.6e-26 90.7 0.6 2.7e-12 46.3 0.2 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EMG48135.1 - 1.6e-12 48.2 0.0 7.5e-07 29.7 0.0 3.8 3 1 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 EMG48135.1 - 3e-10 40.1 0.0 0.00099 18.9 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EMG48135.1 - 7.8e-09 35.6 0.1 0.0083 16.1 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMG48135.1 - 1.3e-08 35.2 0.0 0.0025 17.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EMG48135.1 - 8.6e-08 32.6 2.8 0.0018 18.6 0.0 4.6 3 2 3 6 6 4 1 AAA domain AAA_14 PF13173.6 EMG48135.1 - 2.6e-07 30.7 0.0 0.0016 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EMG48135.1 - 6.8e-07 28.8 0.0 0.026 13.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Bac_DnaA PF00308.18 EMG48135.1 - 8.9e-07 29.0 0.0 5.5e-05 23.1 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_33 PF13671.6 EMG48135.1 - 1.6e-06 28.3 0.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 EMG48135.1 - 2.2e-06 27.7 0.0 0.029 14.3 0.1 2.9 2 1 1 3 3 3 2 Rad17 P-loop domain RNA_helicase PF00910.22 EMG48135.1 - 4.8e-06 26.9 0.0 0.051 14.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 EMG48135.1 - 1.2e-05 24.8 0.1 0.036 13.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EMG48135.1 - 0.00026 20.9 0.1 0.058 13.2 0.0 2.5 3 0 0 3 3 2 1 AAA domain CDC48_N PF02359.18 EMG48135.1 - 0.0003 20.9 0.0 0.0009 19.4 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_28 PF13521.6 EMG48135.1 - 0.00041 20.6 0.0 0.93 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EMG48135.1 - 0.00043 20.8 0.0 0.021 15.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 EMG48135.1 - 0.00055 19.5 0.1 0.77 9.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 EMG48135.1 - 0.0007 19.6 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EMG48135.1 - 0.00072 19.4 0.0 0.061 13.1 0.0 3.4 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EMG48135.1 - 0.0015 18.4 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EMG48135.1 - 0.0021 17.6 4.6 0.76 9.3 0.0 3.9 2 2 1 3 3 3 1 AAA domain AAA_30 PF13604.6 EMG48135.1 - 0.0035 17.1 0.1 0.039 13.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EMG48135.1 - 0.0043 17.0 0.4 0.048 13.6 0.0 2.6 3 0 0 3 3 2 1 NACHT domain IstB_IS21 PF01695.17 EMG48135.1 - 0.0062 16.3 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.6 EMG48135.1 - 0.0081 16.5 0.4 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EMG48135.1 - 0.0092 15.3 0.1 3.7 6.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin ATPase PF06745.13 EMG48135.1 - 0.011 15.1 0.8 9.2 5.5 0.1 3.4 2 1 0 3 3 3 0 KaiC Molydop_binding PF01568.21 EMG48135.1 - 0.011 15.7 0.0 0.048 13.7 0.0 2.0 2 0 0 2 2 1 0 Molydopterin dinucleotide binding domain DUF815 PF05673.13 EMG48135.1 - 0.015 14.5 0.0 0.38 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 EMG48135.1 - 0.015 15.0 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EMG48135.1 - 0.027 14.4 0.1 17 5.2 0.0 3.5 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EMG48135.1 - 0.028 15.0 0.0 3.8 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 EMG48135.1 - 0.052 13.7 0.0 2.5 8.2 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain Desmo_N PF06771.11 EMG48135.1 - 0.075 13.4 0.1 12 6.3 0.0 3.6 4 0 0 4 4 3 0 Viral Desmoplakin N-terminus Sigma54_activat PF00158.26 EMG48135.1 - 0.079 12.7 0.0 12 5.5 0.0 3.2 3 1 0 3 3 2 0 Sigma-54 interaction domain Vps4_C PF09336.10 EMG48135.1 - 0.11 12.5 0.0 0.69 10.0 0.0 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AFG1_ATPase PF03969.16 EMG48135.1 - 0.13 11.1 0.0 0.61 8.9 0.0 2.0 2 0 0 2 2 2 0 AFG1-like ATPase STPPase_N PF16891.5 EMG48135.1 - 5.9 7.4 5.1 20 5.8 0.2 4.1 4 0 0 4 4 3 0 Serine-threonine protein phosphatase N-terminal domain DSHCT PF08148.12 EMG48136.1 - 3.2e-48 163.5 0.7 6.7e-48 162.5 0.7 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EMG48136.1 - 8.2e-35 119.6 0.2 2e-34 118.3 0.2 1.7 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 EMG48136.1 - 4.9e-20 72.0 0.0 1.1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 EMG48136.1 - 7.5e-19 68.7 1.3 1.9e-18 67.3 1.3 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 EMG48136.1 - 2e-06 28.1 0.0 8.9e-06 26.0 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG48136.1 - 1.3e-05 25.3 0.0 3.8e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EMG48136.1 - 0.16 12.2 0.0 0.52 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 EMG48137.1 - 3.3e-58 195.8 0.0 4e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG48137.1 - 9.7e-35 119.4 0.0 1.5e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG48137.1 - 1.7e-15 56.9 0.0 1.9e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMG48137.1 - 5.7e-07 29.1 0.0 7.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMG48137.1 - 5.3e-05 23.3 0.0 8.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMG48137.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EMG48137.1 - 0.00053 20.4 0.0 0.00067 20.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMG48137.1 - 0.00069 19.6 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase N2227 PF07942.12 EMG48138.1 - 1.5e-65 221.1 0.0 2.8e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 EMG48138.1 - 3.2e-05 24.6 0.0 0.0031 18.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG48138.1 - 6.5e-05 23.5 0.0 0.0038 17.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMG48138.1 - 0.00018 21.3 0.1 0.059 13.2 0.1 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EMG48138.1 - 0.0059 17.3 0.0 0.87 10.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EMG48138.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family NMT1 PF09084.11 EMG48139.1 - 2.7e-12 47.1 0.0 4.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EMG48139.1 - 2.9e-05 23.9 0.0 4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family DUF3834 PF12916.7 EMG48139.1 - 0.022 14.0 0.0 0.062 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) TPR_12 PF13424.6 EMG48140.1 - 3.7e-05 23.9 0.9 0.00029 21.1 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EMG48140.1 - 0.0037 16.7 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 EMG48140.1 - 0.0052 16.5 0.0 0.83 9.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMG48140.1 - 0.013 15.5 0.0 2.3 8.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 EMG48140.1 - 0.11 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain DUF3744 PF12558.8 EMG48140.1 - 1.4 9.7 8.6 0.17 12.7 0.9 3.3 3 0 0 3 3 3 0 ATP-binding cassette cobalt transporter DASH_Dad4 PF08650.10 EMG48141.1 - 1.4e-14 53.8 2.4 1.5e-14 53.7 2.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DUF1744 PF08490.12 EMG48142.1 - 1.4e-144 481.6 1.3 2.1e-144 481.0 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EMG48142.1 - 3.7e-78 263.0 4.1 3.7e-78 263.0 4.1 3.0 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EMG48142.1 - 9.6e-16 57.5 0.0 5.2e-14 51.8 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EMG48142.1 - 3.7e-06 26.8 0.2 1.4e-05 24.9 0.2 2.0 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EMG48142.1 - 4.6e-05 23.5 0.6 0.00021 21.3 0.1 2.5 2 0 0 2 2 2 1 RNase_H superfamily NAPRTase_C PF17956.1 EMG48142.1 - 0.00061 20.2 0.2 0.0047 17.3 0.0 2.7 3 0 0 3 3 3 1 Nicotinate phosphoribosyltransferase C-terminal domain zf-DNA_Pol PF08996.10 EMG48142.1 - 2.7 7.7 10.0 6.1 6.6 10.0 1.5 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Phage_int_SAM_1 PF02899.17 EMG48143.1 - 1.2e-06 28.8 6.4 0.0012 19.1 0.3 3.4 3 0 0 3 3 3 2 Phage integrase, N-terminal SAM-like domain GCR1_C PF12550.8 EMG48143.1 - 1.7e-06 28.2 0.7 1.4e-05 25.3 0.7 2.7 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_4 PF13495.6 EMG48143.1 - 0.00054 20.4 13.1 0.023 15.1 0.7 4.0 3 2 1 4 4 4 2 Phage integrase, N-terminal SAM-like domain DUF1864 PF08933.11 EMG48143.1 - 0.0098 14.7 0.1 0.044 12.5 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1864) DsrD PF08679.11 EMG48143.1 - 0.022 15.0 0.1 0.11 12.7 0.1 2.3 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) SATase_N PF06426.14 EMG48143.1 - 0.074 13.4 1.7 8.7 6.8 0.2 3.1 3 0 0 3 3 3 0 Serine acetyltransferase, N-terminal Alg6_Alg8 PF03155.15 EMG48144.1 - 2.7e-92 310.3 9.1 3.5e-92 309.9 9.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family KH_1 PF00013.29 EMG48145.1 - 9.6e-10 38.2 0.4 6.5e-09 35.5 0.0 2.5 2 1 0 2 2 2 1 KH domain KH_4 PF13083.6 EMG48145.1 - 0.00049 19.9 0.1 0.0028 17.5 0.0 2.3 3 0 0 3 3 3 1 KH domain HSP70 PF00012.20 EMG48146.1 - 7.2e-230 764.2 10.3 8e-230 764.1 10.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMG48146.1 - 3.6e-17 62.2 0.7 1.7e-15 56.7 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EMG48146.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain ATP-synt_DE PF00401.20 EMG48146.1 - 0.0052 17.0 1.0 0.0052 17.0 1.0 2.8 2 1 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DDR PF08841.10 EMG48146.1 - 0.033 13.2 0.7 0.57 9.1 0.3 2.5 2 1 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain RIO1 PF01163.22 EMG48147.1 - 1.1e-43 149.0 0.8 2e-43 148.2 0.8 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EMG48147.1 - 2.6e-33 114.1 0.2 2.5e-32 110.9 0.1 2.2 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 EMG48147.1 - 2.8e-07 30.7 0.1 0.0054 16.7 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EMG48147.1 - 2.3e-05 23.8 0.1 0.0012 18.2 0.1 2.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMG48147.1 - 0.027 13.2 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase NOA36 PF06524.12 EMG48147.1 - 0.4 10.0 23.7 0.66 9.2 23.7 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EMG48147.1 - 0.73 8.0 24.4 1 7.5 24.4 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 EMG48147.1 - 1.6 8.4 23.5 2.5 7.8 23.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RPN2_C PF18004.1 EMG48147.1 - 4.1 7.3 10.0 7.5 6.5 10.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_pol_3_Rpc31 PF11705.8 EMG48147.1 - 6.5 6.9 27.8 11 6.2 27.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 EMG48147.1 - 9.1 6.2 14.7 13 5.6 14.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DCP2 PF05026.13 EMG48149.1 - 3.4e-29 101.0 2.3 2.6e-28 98.2 0.1 2.6 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 EMG48149.1 - 2.8e-15 56.5 0.0 1.1e-14 54.6 0.0 2.0 1 0 0 1 1 1 1 NUDIX domain Orthopox_F6 PF06601.12 EMG48149.1 - 0.098 12.8 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Orthopoxvirus F6 protein ATP-synt_10 PF05176.14 EMG48150.1 - 5.6e-99 330.5 0.1 6.4e-99 330.3 0.1 1.0 1 0 0 1 1 1 1 ATP10 protein Ribosomal_S10 PF00338.22 EMG48151.1 - 5.9e-27 93.8 0.6 8.1e-27 93.3 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e RasGEF PF00617.19 EMG48152.1 - 5.6e-43 147.2 3.6 5.6e-43 147.2 3.6 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EMG48152.1 - 5.5e-11 42.6 0.3 5.5e-11 42.6 0.3 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 EMG48152.1 - 0.00094 18.8 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Imm53 PF15580.6 EMG48152.1 - 0.038 13.7 0.1 1.5 8.6 0.0 3.0 2 0 0 2 2 2 0 Immunity protein 53 Ferric_reduct PF01794.19 EMG48153.1 - 3.1e-24 85.5 19.2 3.1e-24 85.5 19.2 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EMG48153.1 - 2e-21 76.1 0.0 3.6e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EMG48153.1 - 1.2e-20 74.2 0.1 2.4e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4131 PF13567.6 EMG48153.1 - 2.4 7.8 5.4 6.6 6.4 5.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FAD_binding_8 PF08022.12 EMG48154.1 - 2.4e-22 79.1 0.0 7.6e-22 77.5 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EMG48154.1 - 1.3e-21 77.3 0.1 3.4e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EMG48154.1 - 2.7e-19 69.5 14.6 2.7e-19 69.5 14.6 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component DEAD PF00270.29 EMG48154.1 - 4.6e-09 36.3 0.4 1.6e-08 34.5 0.4 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 EMG48154.1 - 0.0026 16.9 0.1 0.005 15.9 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein NAD_binding_1 PF00175.21 EMG48154.1 - 0.035 14.7 0.0 0.11 13.2 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain LIP PF03583.14 EMG48155.1 - 2e-120 401.4 0.5 2.4e-120 401.2 0.5 1.0 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.20 EMG48155.1 - 0.013 15.1 0.2 1.9 8.1 0.0 2.8 3 0 0 3 3 3 0 alpha/beta hydrolase fold DUF824 PF05688.11 EMG48155.1 - 0.029 14.2 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) Peptidase_S9 PF00326.21 EMG48155.1 - 0.041 13.3 3.0 4.6 6.7 0.0 2.9 3 1 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EMG48155.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PIF1 PF05970.14 EMG48156.1 - 1.1e-61 209.0 3.1 4.1e-47 161.1 0.6 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EMG48156.1 - 1.8e-20 73.5 0.0 5.9e-20 71.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMG48156.1 - 9.1e-10 39.0 0.0 2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EMG48156.1 - 2.6e-05 22.4 0.4 0.00068 17.7 0.0 2.3 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 EMG48156.1 - 7e-05 23.1 0.1 0.00029 21.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EMG48156.1 - 0.00052 20.5 0.0 0.0016 18.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 EMG48156.1 - 0.0012 18.6 0.0 0.007 16.2 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 EMG48156.1 - 0.007 15.9 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 EMG48156.1 - 0.01 15.1 0.6 0.15 11.3 0.6 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EMG48156.1 - 0.015 15.1 0.4 2.8 7.6 0.3 2.9 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EMG48156.1 - 0.017 15.5 0.1 0.046 14.1 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain SH3_13 PF18335.1 EMG48156.1 - 0.026 14.3 0.1 0.087 12.7 0.1 1.9 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain NACHT PF05729.12 EMG48156.1 - 0.031 14.2 0.1 0.1 12.5 0.1 1.9 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 EMG48156.1 - 0.031 13.6 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 EMG48156.1 - 0.096 11.7 0.1 0.19 10.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 EMG48156.1 - 0.11 12.6 0.7 0.68 10.0 0.1 2.5 2 1 0 2 2 1 0 AAA domain AAA_5 PF07728.14 EMG48156.1 - 0.14 12.1 1.0 1.5 8.8 0.4 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EMG48156.1 - 0.16 11.9 0.8 4.4 7.2 0.1 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Helicase_RecD PF05127.14 EMG48156.1 - 0.21 11.5 0.9 1.6 8.6 0.9 2.3 1 1 0 1 1 1 0 Helicase Sec39 PF08314.11 EMG48157.1 - 2.8e-51 174.9 28.1 6.4e-51 173.7 28.1 1.5 1 1 0 1 1 1 1 Secretory pathway protein Sec39 LSM PF01423.22 EMG48158.1 - 5.1e-18 64.5 0.0 6e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EMG48158.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.6 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Mnd1 PF03962.15 EMG48159.1 - 6e-11 42.5 0.3 6e-11 42.5 0.3 2.0 2 0 0 2 2 2 1 Mnd1 HTH domain DUF4507 PF14964.6 EMG48159.1 - 0.0012 17.8 0.7 0.0015 17.5 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) TMF_TATA_bd PF12325.8 EMG48159.1 - 0.01 16.1 5.5 0.019 15.1 5.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 EMG48159.1 - 0.013 15.3 1.9 0.53 10.1 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator YueH PF14166.6 EMG48159.1 - 0.031 14.1 2.7 0.059 13.2 0.2 2.2 2 0 0 2 2 2 0 YueH-like protein YlqD PF11068.8 EMG48159.1 - 0.046 14.1 4.0 0.061 13.7 4.0 1.2 1 0 0 1 1 1 0 YlqD protein Tn7_TnsC_Int PF11426.8 EMG48159.1 - 0.061 13.5 2.8 0.16 12.1 0.5 2.3 2 0 0 2 2 2 0 Tn7 transposition regulator TnsC FapA PF03961.13 EMG48159.1 - 0.08 11.5 2.3 0.089 11.4 2.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A POX PF07526.11 EMG48159.1 - 0.17 12.5 4.5 1 9.9 4.5 2.0 1 1 0 1 1 1 0 Associated with HOX DUF1664 PF07889.12 EMG48159.1 - 0.17 11.9 4.0 0.77 9.8 4.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1043 PF06295.12 EMG48159.1 - 0.36 10.8 5.8 1.5 8.8 5.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Sugar_tr PF00083.24 EMG48160.1 - 1.2e-47 162.8 14.7 1.4e-47 162.7 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2905 PF11146.8 EMG48160.1 - 0.45 10.7 3.6 3.4 7.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) LysE PF01810.18 EMG48160.1 - 5 6.5 13.1 1.6 8.2 1.9 2.7 1 1 1 3 3 3 0 LysE type translocator Sugar_tr PF00083.24 EMG48161.1 - 2.3e-46 158.6 12.6 2.9e-46 158.3 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG48161.1 - 3.2e-15 55.9 13.3 3.9e-15 55.6 13.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GMC_oxred_N PF00732.19 EMG48162.1 - 9.1e-22 77.8 0.2 1.1e-21 77.5 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMG48162.1 - 3.7e-05 23.0 0.0 6.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMG48162.1 - 6.8e-05 23.0 0.1 0.00013 22.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMG48162.1 - 0.0065 15.7 0.1 0.0091 15.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Stirrup PF09061.6 EMG48162.1 - 0.077 13.2 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Stirrup FAD_binding_3 PF01494.19 EMG48162.1 - 0.082 12.1 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_C PF05199.13 EMG48163.1 - 7.6e-27 94.6 0.2 1.1e-26 94.0 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase AAA_2 PF07724.14 EMG48164.1 - 7.4e-46 156.4 0.1 2.7e-45 154.6 0.0 2.0 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 EMG48164.1 - 4.3e-22 78.0 0.2 1.1e-21 76.6 0.2 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EMG48164.1 - 2.3e-10 40.6 0.3 5.2e-09 36.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EMG48164.1 - 3.1e-07 30.9 0.0 8.4e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMG48164.1 - 4.3e-07 29.8 0.0 2e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EMG48164.1 - 0.00032 20.2 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EMG48164.1 - 0.00034 21.0 0.1 0.0093 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMG48164.1 - 0.0036 17.6 0.0 0.068 13.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMG48164.1 - 0.0037 17.3 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EMG48164.1 - 0.016 15.1 0.0 0.062 13.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 EMG48164.1 - 0.023 14.8 0.0 0.069 13.3 0.0 1.7 2 0 0 2 2 1 0 Torsin SRP54 PF00448.22 EMG48164.1 - 0.041 13.5 0.1 0.23 11.1 0.0 2.2 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EMG48164.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 EMG48164.1 - 0.064 11.9 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.6 EMG48164.1 - 0.086 13.4 0.9 1.3 9.6 0.8 2.8 1 1 0 1 1 1 0 AAA domain DUF2138 PF09909.9 EMG48164.1 - 0.1 10.9 0.2 0.14 10.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) DUF5129 PF17173.4 EMG48164.1 - 0.12 11.4 1.3 0.2 10.7 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5129) APS_kinase PF01583.20 EMG48164.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ArfGap PF01412.18 EMG48165.1 - 1.1e-30 106.1 1.2 2.7e-30 104.9 0.0 2.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf HOIP-UBA PF16678.5 EMG48165.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair UBA PF00627.31 EMG48165.1 - 0.14 12.1 0.4 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain Clp_N PF02861.20 EMG48166.1 - 1.6e-13 50.5 2.1 4.8e-09 36.2 0.3 3.5 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA PF00004.29 EMG48166.1 - 2.3e-13 50.7 0.0 6.7e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMG48166.1 - 1.4e-08 35.3 0.9 3.2e-06 27.6 0.3 2.8 2 1 1 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 EMG48166.1 - 6.2e-06 26.3 0.9 0.083 12.8 0.1 2.6 1 1 0 2 2 2 2 ATPase domain predominantly from Archaea TniB PF05621.11 EMG48166.1 - 1.3e-05 24.7 0.0 0.0016 17.9 0.0 2.3 1 1 0 1 1 1 1 Bacterial TniB protein AAA_7 PF12775.7 EMG48166.1 - 0.0021 17.6 0.0 0.025 14.1 0.0 2.5 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 EMG48166.1 - 0.0033 17.2 0.0 0.0077 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMG48166.1 - 0.0045 17.0 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMG48166.1 - 0.0047 17.2 0.3 0.11 12.8 0.2 2.8 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 EMG48166.1 - 0.0074 16.6 0.6 0.61 10.4 0.0 2.6 2 2 1 3 3 3 1 AAA domain AAA_lid_9 PF17871.1 EMG48166.1 - 0.0077 16.1 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA lid domain NACHT PF05729.12 EMG48166.1 - 0.0086 16.0 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 1 NACHT domain TsaE PF02367.17 EMG48166.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EMG48166.1 - 0.026 14.4 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Roc PF08477.13 EMG48166.1 - 0.031 14.5 0.0 0.089 13.0 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EMG48166.1 - 0.05 12.8 0.3 0.24 10.5 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 EMG48166.1 - 0.095 12.4 0.6 4.8 6.9 0.6 2.5 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_8 PF12780.7 EMG48166.1 - 0.66 9.2 4.6 0.37 10.1 0.9 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region D4 CDP-OH_P_transf PF01066.21 EMG48167.1 - 8.6e-14 52.1 0.5 8.6e-14 52.1 0.5 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4181 PF13789.6 EMG48167.1 - 0.2 11.9 0.2 0.2 11.9 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4181) MtN3_slv PF03083.16 EMG48167.1 - 0.85 9.7 0.1 0.85 9.7 0.1 3.4 3 1 1 4 4 4 0 Sugar efflux transporter for intercellular exchange DUF3270 PF11674.8 EMG48167.1 - 3.4 7.9 5.6 9.7 6.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3270) ParA PF10609.9 EMG48169.1 - 2.6e-92 308.7 0.0 3.1e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EMG48169.1 - 4e-07 30.1 0.0 2e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMG48169.1 - 2.7e-05 24.2 0.1 0.00031 20.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EMG48169.1 - 0.00013 21.3 0.5 0.0018 17.5 0.1 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 EMG48169.1 - 0.0017 17.7 0.0 0.0037 16.6 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ RsgA_GTPase PF03193.16 EMG48169.1 - 0.012 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase CBP_BcsQ PF06564.12 EMG48169.1 - 0.035 13.6 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EMG48169.1 - 0.045 13.3 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 EMG48169.1 - 0.073 12.5 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 EMG48169.1 - 0.16 11.8 0.0 0.77 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EMG48169.1 - 0.21 11.3 0.1 0.24 11.0 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain Nucleoporin2 PF04096.14 EMG48170.1 - 2.4e-39 134.8 0.4 8.9e-39 133.0 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nup96 PF12110.8 EMG48170.1 - 2.9e-27 95.5 0.0 5.8e-18 65.0 0.0 2.4 1 1 1 2 2 2 2 Nuclear protein 96 Nucleoporin_FG PF13634.6 EMG48170.1 - 1.8e-12 47.9 102.2 1.4e-07 32.2 28.4 4.5 1 1 3 4 4 4 4 Nucleoporin FG repeat region YjeF_N PF03853.15 EMG48171.1 - 1.1e-32 113.3 0.0 1.6e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EMG48171.1 - 1.5e-06 29.0 11.6 1.5e-06 29.0 11.6 2.2 2 2 0 2 2 2 1 FDF domain Frag1 PF10277.9 EMG48174.1 - 2.1e-63 213.8 20.6 2.5e-63 213.6 20.6 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Polysacc_synt_C PF14667.6 EMG48174.1 - 0.0092 16.1 3.0 0.0092 16.1 3.0 3.0 3 0 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain GWT1 PF06423.12 EMG48174.1 - 2.2 8.4 10.8 0.11 12.6 4.6 2.2 2 1 0 2 2 2 0 GWT1 Cation_ATPase_C PF00689.21 EMG48174.1 - 5.2 6.7 18.6 0.25 11.0 10.5 2.1 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus U-box PF04564.15 EMG48175.1 - 2.5e-25 88.4 0.3 6e-25 87.2 0.0 1.8 2 0 0 2 2 2 1 U-box domain V_ATPase_I PF01496.19 EMG48176.1 - 0 1013.3 1.9 0 1013.1 1.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family RIX1 PF08167.12 EMG48177.1 - 4.7e-42 143.9 1.7 1.1e-41 142.7 1.7 1.7 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis ANAPC5 PF12862.7 EMG48178.1 - 9.9e-32 108.9 5.6 9.9e-32 108.9 5.6 3.4 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 EMG48178.1 - 0.054 13.7 2.3 3 8.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 EMG48178.1 - 0.077 12.2 0.3 4.1 6.5 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat N6-adenineMlase PF10237.9 EMG48179.1 - 1.6e-52 177.5 0.2 1.6e-52 177.5 0.2 1.4 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase PAT1 PF09770.9 EMG48180.1 - 2.2e-107 360.4 79.5 3e-53 181.3 55.4 3.2 1 1 2 3 3 3 3 Topoisomerase II-associated protein PAT1 Chorismate_bind PF00425.18 EMG48181.1 - 1e-74 251.4 0.0 6.1e-74 248.8 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.28 EMG48181.1 - 2.3e-30 105.8 0.0 3.9e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EMG48181.1 - 2.1e-16 60.4 0.5 5e-15 56.0 0.1 2.9 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EMG48181.1 - 1.9e-05 24.5 0.0 3.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Uso1_p115_head PF04869.14 EMG48182.1 - 3.5e-116 387.7 0.2 3.5e-116 387.7 0.2 3.3 3 0 0 3 3 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EMG48182.1 - 4e-17 62.8 33.2 4e-17 62.8 33.2 17.9 2 1 15 17 17 12 1 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.21 EMG48182.1 - 9.4e-11 41.8 282.8 8.9e-05 22.2 32.0 9.5 2 1 8 10 10 10 7 Intermediate filament protein ATG16 PF08614.11 EMG48182.1 - 1.9e-08 34.8 326.6 0.051 13.8 18.7 13.6 2 1 11 14 14 14 10 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EMG48182.1 - 1.2e-07 30.9 349.0 0.0029 16.5 37.6 13.7 2 1 9 13 13 13 8 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EMG48182.1 - 0.00019 21.5 348.5 0.0007 19.7 8.2 16.8 2 1 14 17 17 16 9 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 EMG48182.1 - 0.00028 20.5 45.4 0.00028 20.5 45.4 11.9 2 1 8 12 12 11 1 Mechanosensitive ion channel porin domain HMMR_N PF15905.5 EMG48182.1 - 0.00072 19.1 49.3 0.00072 19.1 49.3 12.1 2 1 9 12 12 12 5 Hyaluronan mediated motility receptor N-terminal Syntaxin_2 PF14523.6 EMG48182.1 - 0.00076 19.8 13.6 0.00076 19.8 13.6 17.0 3 2 12 16 16 12 3 Syntaxin-like protein BRE1 PF08647.11 EMG48182.1 - 0.0019 18.2 16.9 0.0019 18.2 16.9 19.4 3 2 17 20 20 13 3 BRE1 E3 ubiquitin ligase Arm_vescicular PF18770.1 EMG48182.1 - 0.0027 17.6 0.4 0.0073 16.2 0.1 1.9 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor HEAT_2 PF13646.6 EMG48182.1 - 0.0065 16.8 0.0 0.55 10.7 0.0 3.3 2 1 0 2 2 2 1 HEAT repeats Golgin_A5 PF09787.9 EMG48182.1 - 0.022 14.2 311.9 0.014 14.9 19.9 13.9 2 1 12 14 14 14 0 Golgin subfamily A member 5 DUF3584 PF12128.8 EMG48182.1 - 0.025 12.1 289.8 0.001 16.7 53.3 8.0 2 1 8 10 10 10 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 EMG48182.1 - 0.069 11.8 294.0 0.024 13.3 29.8 8.5 2 1 7 9 9 9 0 AAA domain Baculo_PEP_C PF04513.12 EMG48182.1 - 0.16 12.0 177.6 0.047 13.7 2.8 17.1 3 1 13 19 19 18 0 Baculovirus polyhedron envelope protein, PEP, C terminus IKI3 PF04762.12 EMG48183.1 - 0 1144.3 4.5 0 1144.0 4.5 1.1 1 0 0 1 1 1 1 IKI3 family Clathrin PF00637.20 EMG48183.1 - 0.0016 18.3 1.0 0.0078 16.1 1.0 2.2 1 0 0 1 1 1 1 Region in Clathrin and VPS DUF4717 PF15838.5 EMG48183.1 - 0.25 11.4 1.0 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4717) ANAPC3 PF12895.7 EMG48183.1 - 0.88 9.8 4.6 14 6.0 0.1 4.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 EF1_GNE PF00736.19 EMG48184.1 - 5.7e-31 106.5 1.0 5.7e-31 106.5 1.0 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EMG48184.1 - 8.2e-13 48.5 5.5 8.2e-13 48.5 5.5 2.7 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region Fungal_trans_2 PF11951.8 EMG48185.1 - 6.7e-24 84.4 1.1 1.3e-23 83.5 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MIEAP PF16026.5 EMG48185.1 - 0.32 11.2 1.8 0.84 9.8 0.2 2.4 3 0 0 3 3 3 0 Mitochondria-eating protein Pkinase PF00069.25 EMG48186.1 - 1.8e-49 168.5 0.1 1.4e-33 116.4 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMG48186.1 - 5.9e-24 84.7 0.1 2.6e-23 82.6 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG48186.1 - 0.00015 20.7 0.9 0.00032 19.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EMG48186.1 - 0.0082 15.5 0.0 0.098 11.9 0.0 2.3 1 1 0 1 1 1 1 Kinase-like MAR_sialic_bdg PF10564.9 EMG48186.1 - 0.19 11.8 0.7 0.42 10.7 0.7 1.5 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat Pkinase PF00069.25 EMG48187.1 - 4.8e-61 206.4 0.0 1.1e-60 205.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG48187.1 - 1.9e-42 145.4 0.0 3.1e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 EMG48187.1 - 3.7e-35 121.5 4.3 4.6e-19 68.8 2.2 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3543) MIT PF04212.18 EMG48187.1 - 0.00088 19.3 3.9 0.0014 18.6 2.7 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Kinase-like PF14531.6 EMG48187.1 - 0.0037 16.6 0.0 0.074 12.3 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EMG48187.1 - 0.081 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Med12 PF09497.10 EMG48188.1 - 9.7e-23 80.2 0.1 2.3e-22 79.0 0.1 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 V-ATPase_H_C PF11698.8 EMG48188.1 - 2.5 8.2 9.8 0.41 10.8 0.1 4.1 4 0 0 4 4 4 0 V-ATPase subunit H Myosin_head PF00063.21 EMG48189.1 - 1.6e-230 766.9 10.8 2e-230 766.6 10.8 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EMG48189.1 - 6.6e-48 162.9 0.0 1.6e-47 161.7 0.0 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Hpr_kinase_C PF07475.12 EMG48189.1 - 0.012 15.2 0.1 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 EMG48189.1 - 0.033 14.6 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain SH3_1 PF00018.28 EMG48189.1 - 0.046 13.3 0.1 0.087 12.4 0.1 1.5 1 0 0 1 1 1 0 SH3 domain RsgA_GTPase PF03193.16 EMG48189.1 - 0.052 13.5 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EMG48189.1 - 0.064 13.5 0.0 0.34 11.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain IQ PF00612.27 EMG48189.1 - 1.5 8.8 10.4 3.8 7.6 4.3 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif zf-H2C2_2 PF13465.6 EMG48190.1 - 3.8e-15 55.5 45.8 2.9e-08 33.8 0.4 8.7 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2 PF00096.26 EMG48190.1 - 1.5e-14 53.5 57.4 6.9e-05 23.1 0.5 8.5 9 0 0 9 9 8 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG48190.1 - 2.5e-11 43.4 49.4 0.0022 18.7 0.2 9.9 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EMG48190.1 - 4.9e-05 23.0 20.1 0.0007 19.3 1.6 5.6 4 1 1 5 5 5 2 zinc-finger C2H2-type FOXP-CC PF16159.5 EMG48190.1 - 0.00019 22.0 5.9 0.00055 20.5 1.0 8.3 5 3 3 8 8 7 3 FOXP coiled-coil domain Zap1_zf2 PF18217.1 EMG48190.1 - 0.00053 19.9 5.4 0.00053 19.9 5.4 5.7 6 0 0 6 6 5 1 Zap1 zinc finger 2 zf-C2H2_6 PF13912.6 EMG48190.1 - 0.0044 17.0 21.8 0.16 12.0 0.7 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger YajC PF02699.15 EMG48190.1 - 0.033 14.1 0.6 0.033 14.1 0.6 1.7 2 0 0 2 2 2 0 Preprotein translocase subunit AARP2CN PF08142.12 EMG48190.1 - 0.11 12.6 0.9 0.33 11.1 0.9 1.7 1 0 0 1 1 1 0 AARP2CN (NUC121) domain zf-C2H2_jaz PF12171.8 EMG48190.1 - 0.28 11.5 0.1 0.28 11.5 0.1 5.9 7 0 0 7 7 6 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMG48190.1 - 0.99 9.9 42.9 0.077 13.4 1.0 7.3 7 0 0 7 7 6 0 Zinc-finger of C2H2 type PDDEXK_6 PF04720.12 EMG48191.1 - 5.2 7.0 8.9 6.3 6.7 8.2 1.5 1 1 0 1 1 1 0 PDDEXK-like family of unknown function Glyco_hydro_72 PF03198.14 EMG48192.1 - 9.8e-149 494.8 11.4 1.7e-148 494.0 11.4 1.4 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EMG48192.1 - 1.8e-26 92.6 5.6 6.4e-26 90.9 5.6 2.0 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EMG48192.1 - 9e-06 25.0 2.9 2.2e-05 23.7 2.9 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain SR-25 PF10500.9 EMG48192.1 - 1 8.9 15.5 2.1 7.9 15.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 EMG48192.1 - 5.2 5.5 4.5 14 4.1 4.7 1.5 2 0 0 2 2 2 0 Macoilin family B-block_TFIIIC PF04182.12 EMG48193.1 - 2e-18 66.3 0.1 1.4e-16 60.4 0.0 3.4 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC G-patch PF01585.23 EMG48193.1 - 4.8e-12 45.6 0.9 1e-11 44.5 0.3 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EMG48193.1 - 0.0013 18.7 0.1 0.0013 18.7 0.1 3.8 2 1 0 2 2 2 1 G-patch domain HTH_20 PF12840.7 EMG48193.1 - 0.032 14.3 0.3 17 5.6 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain MarR_2 PF12802.7 EMG48193.1 - 0.037 13.9 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 MarR family zf-MIZ PF02891.20 EMG48194.1 - 2e-07 30.6 0.2 2.3e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger BrnA_antitoxin PF14384.6 EMG48194.1 - 0.28 11.7 0.1 0.28 11.7 0.1 2.3 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system DUF3294 PF07957.11 EMG48195.1 - 2.1e-73 246.6 7.6 2.5e-73 246.4 7.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF3826 PF12875.7 EMG48195.1 - 0.042 14.0 5.5 0.3 11.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3826) DUF1664 PF07889.12 EMG48195.1 - 0.73 9.9 6.2 0.4 10.7 3.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 EMG48195.1 - 1.4 9.5 6.0 4 8.1 1.7 2.6 1 1 1 2 2 2 0 SlyX Sec66 PF09802.9 EMG48196.1 - 1.1e-61 207.6 1.3 1.2e-61 207.4 1.3 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 MIP PF00230.20 EMG48197.1 - 6.3e-45 153.6 16.0 7.6e-45 153.4 16.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein RabGAP-TBC PF00566.18 EMG48199.1 - 6.1e-45 153.5 10.2 3.9e-44 150.9 10.2 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain HSP70 PF00012.20 EMG48200.1 - 2.2e-78 264.0 2.9 7.3e-78 262.2 1.4 1.9 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EMG48200.1 - 3.1e-08 32.8 0.0 4.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Myb_DNA-binding PF00249.31 EMG48202.1 - 4.5e-35 119.6 14.9 3e-14 52.9 0.2 4.5 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMG48202.1 - 2e-32 111.2 2.0 8e-13 48.4 0.0 4.2 2 2 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EMG48202.1 - 0.00033 20.7 3.5 1.1 9.3 0.0 4.7 3 1 2 5 5 5 2 SLIDE Myb_DNA-bind_2 PF08914.11 EMG48202.1 - 0.0069 16.5 0.0 0.25 11.5 0.0 3.1 3 0 0 3 3 3 1 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 EMG48202.1 - 0.032 14.1 1.9 2.2 8.2 0.3 3.8 3 1 0 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EMG48202.1 - 0.044 14.2 6.9 0.22 11.9 0.1 4.0 2 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain CENP-B_dimeris PF09026.10 EMG48202.1 - 0.15 12.4 10.9 0.67 10.4 10.9 2.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EMG48202.1 - 0.39 10.0 9.5 1.4 8.2 9.5 1.9 1 0 0 1 1 1 0 NOA36 protein THF_DHG_CYH PF00763.23 EMG48203.1 - 3e-27 95.2 0.0 5.5e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EMG48203.1 - 1.8e-15 56.7 0.0 4.6e-11 42.3 0.0 3.0 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 EMG48203.1 - 0.0066 16.9 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF4834 PF16118.5 EMG48204.1 - 0.055 14.4 0.1 0.055 14.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SID-1_RNA_chan PF13965.6 EMG48204.1 - 0.1 11.0 0.5 0.11 10.9 0.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ctr PF04145.15 EMG48204.1 - 0.23 12.1 0.1 0.3 11.7 0.1 1.5 1 1 0 1 1 1 0 Ctr copper transporter family LRR19-TM PF15176.6 EMG48204.1 - 0.27 11.3 4.5 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain YqzE PF14038.6 EMG48204.1 - 0.35 10.9 0.1 0.35 10.9 0.1 2.3 4 0 0 4 4 4 0 YqzE-like protein EMC3_TMCO1 PF01956.16 EMG48204.1 - 0.46 10.2 1.9 0.29 10.9 0.2 1.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like OAD_gamma PF04277.13 EMG48204.1 - 0.72 10.5 2.8 1.4 9.6 2.8 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ODV-E18 PF10717.9 EMG48204.1 - 3.7 7.5 4.3 7.4 6.5 4.3 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 O-antigen_lig PF13425.6 EMG48204.1 - 5.6 5.6 9.8 38 2.9 9.8 1.9 1 1 0 1 1 1 0 O-antigen ligase like membrane protein p450 PF00067.22 EMG48205.1 - 7.3e-48 163.4 0.0 9.2e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vac7 PF12751.7 EMG48206.1 - 2.4e-27 96.4 6.4 1.3e-16 61.0 0.0 5.1 3 2 2 5 5 5 3 Vacuolar segregation subunit 7 TraG_N PF07916.11 EMG48207.1 - 1.3 7.8 7.6 1.8 7.3 7.6 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Rick_17kDa_Anti PF05433.15 EMG48207.1 - 5.9 6.8 13.3 35 4.4 0.8 3.5 2 1 1 3 3 3 0 Glycine zipper 2TM domain Exo_endo_phos PF03372.23 EMG48209.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.3 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Kin17_mid PF10357.9 EMG48210.1 - 3.7e-37 127.0 2.8 8.7e-37 125.8 2.8 1.7 1 1 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 EMG48210.1 - 8.9e-07 29.0 2.4 8.9e-07 29.0 2.4 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMG48210.1 - 0.0013 19.0 2.1 0.0013 19.0 2.1 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EMG48210.1 - 0.0043 17.4 1.7 0.03 14.6 0.4 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF5382 PF17354.2 EMG48210.1 - 0.023 13.6 0.1 0.031 13.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5382) UCH PF00443.29 EMG48211.1 - 1e-50 172.7 2.7 1e-50 172.7 2.7 1.8 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMG48211.1 - 8.3e-18 65.0 3.1 1.4e-17 64.3 0.6 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rubredoxin_2 PF18073.1 EMG48211.1 - 0.78 9.5 5.4 8.1 6.3 0.4 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain PAT1 PF09770.9 EMG48211.1 - 2.2 6.4 8.8 3.8 5.6 8.8 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M48 PF01435.18 EMG48212.1 - 1.1e-29 103.6 0.0 2.5e-29 102.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M48 SKG6 PF08693.10 EMG48214.1 - 0.024 14.0 2.3 0.06 12.8 2.3 1.6 1 1 0 1 1 1 0 Transmembrane alpha-helix domain DUF3792 PF12670.7 EMG48214.1 - 0.058 13.6 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) DUF347 PF03988.12 EMG48214.1 - 0.076 13.2 0.2 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) NABP PF07990.12 EMG48214.1 - 0.13 11.7 16.1 0.19 11.2 16.1 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP YajC PF02699.15 EMG48214.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit MFS_1 PF07690.16 EMG48216.1 - 1.6e-22 79.9 7.3 1.6e-22 79.9 7.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EMG48216.1 - 2.8e-17 63.0 3.0 2.8e-17 63.0 3.0 2.1 2 0 0 2 2 2 1 Nodulin-like Sugar_tr PF00083.24 EMG48216.1 - 3.1e-11 42.8 16.2 2.8e-06 26.4 5.3 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Zds_C PF08632.10 EMG48217.1 - 2.2e-30 104.1 2.4 4.3e-30 103.2 2.4 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Cyt-b5 PF00173.28 EMG48218.1 - 4.2e-20 71.7 2.1 1.3e-19 70.1 0.1 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EMG48218.1 - 2.1e-14 54.0 17.6 4.2e-14 53.0 15.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.6 EMG48218.1 - 0.49 10.3 4.1 16 5.4 1.4 3.1 3 0 0 3 3 3 0 Cytochrome oxidase c assembly JAB PF01398.21 EMG48219.1 - 4.5e-30 104.1 0.6 9.9e-30 102.9 0.1 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EMG48219.1 - 9.6e-06 25.4 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EMG48219.1 - 0.1 12.7 2.5 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) BUD22 PF09073.10 EMG48219.1 - 0.25 10.6 20.2 0.35 10.2 20.2 1.2 1 0 0 1 1 1 0 BUD22 UCH PF00443.29 EMG48220.1 - 3.2e-52 177.6 10.2 3.2e-52 177.6 10.2 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMG48220.1 - 6.6e-18 65.4 12.8 6.6e-18 65.4 12.8 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M35 PF02102.15 EMG48220.1 - 0.017 14.0 0.2 0.026 13.4 0.2 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family DUF3484 PF11983.8 EMG48220.1 - 9 7.5 10.3 0.27 12.3 2.8 2.4 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch SHR3_chaperone PF08229.11 EMG48221.1 - 1.3e-73 246.0 0.4 1.3e-73 246.0 0.4 1.6 2 0 0 2 2 2 1 ER membrane protein SH3 DUF4199 PF13858.6 EMG48221.1 - 0.33 11.3 5.7 2.4 8.5 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Ribosomal_L22 PF00237.19 EMG48223.1 - 4e-21 75.2 0.7 8.1e-21 74.2 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Peptidase_U32 PF01136.19 EMG48223.1 - 0.085 12.0 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Peptidase family U32 Yippee-Mis18 PF03226.14 EMG48224.1 - 9.9e-11 41.8 1.5 1.9e-10 40.9 1.5 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EMG48224.1 - 0.13 12.5 3.5 0.22 11.8 2.8 1.8 1 1 0 1 1 1 0 C-terminal domain of RIG-I DUF5470 PF17564.2 EMG48224.1 - 2.3 8.5 12.1 2.7 8.2 0.4 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF5470) Brix PF04427.18 EMG48225.1 - 9.6e-26 91.1 0.2 1.4e-25 90.5 0.2 1.3 1 0 0 1 1 1 1 Brix domain Pyr_redox_2 PF07992.14 EMG48226.1 - 3.8e-24 85.4 0.0 4.7e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMG48226.1 - 4.1e-07 30.1 0.2 0.042 13.8 0.0 3.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMG48226.1 - 1.2e-06 29.0 0.0 0.00059 20.3 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMG48226.1 - 0.0026 17.1 0.1 0.0048 16.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMG48226.1 - 0.037 13.2 0.0 0.081 12.1 0.0 1.5 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Sigma70_r3 PF04539.16 EMG48226.1 - 0.16 12.1 0.4 0.71 10.0 0.1 2.1 2 0 0 2 2 2 0 Sigma-70 region 3 Pyr_redox_2 PF07992.14 EMG48227.1 - 2e-21 76.5 0.0 1.8e-20 73.4 0.0 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMG48227.1 - 2.4e-09 37.6 0.0 9.5e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMG48227.1 - 0.0022 17.2 0.0 0.0057 15.8 0.0 1.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMG48227.1 - 0.0057 16.6 0.0 5.1 7.1 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMG48227.1 - 0.027 13.8 0.0 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMG48227.1 - 0.072 12.7 0.0 3.2 7.2 0.0 2.9 4 0 0 4 4 4 0 FAD dependent oxidoreductase VTC PF09359.10 EMG48228.1 - 1.5e-101 339.4 0.6 3.1e-101 338.4 0.0 1.7 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 EMG48228.1 - 2.8e-14 53.3 4.2 6.7e-14 52.1 4.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 EMG48228.1 - 6.9e-09 36.1 20.1 2.8e-07 30.8 0.7 4.1 4 1 1 5 5 5 3 SPX domain LXG PF04740.12 EMG48228.1 - 0.0017 18.1 1.2 0.67 9.6 0.1 2.6 2 0 0 2 2 2 2 LXG domain of WXG superfamily MazG PF03819.17 EMG48228.1 - 0.0032 17.6 0.0 0.0086 16.2 0.0 1.7 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Polyketide_cyc2 PF10604.9 EMG48229.1 - 1.3e-05 25.5 0.0 1.5e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Peptidase_S10 PF00450.22 EMG48230.1 - 4.2e-109 365.8 0.0 5.1e-109 365.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DAO PF01266.24 EMG48231.1 - 1.5e-15 57.7 0.0 2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMG48231.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMG48231.1 - 0.087 12.0 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IBN_N PF03810.19 EMG48232.1 - 0.0013 18.7 2.2 0.028 14.3 0.1 3.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EMG48232.1 - 0.029 14.4 14.6 0.043 13.9 5.3 5.1 5 1 0 5 5 5 0 Exportin 1-like protein PRANC PF09372.10 EMG48232.1 - 0.11 12.8 2.6 27 5.2 0.0 3.9 3 0 0 3 3 3 0 PRANC domain FGF PF00167.18 EMG48232.1 - 0.14 12.3 0.0 6.2 6.9 0.0 2.7 2 0 0 2 2 2 0 Fibroblast growth factor MCRA PF06100.11 EMG48233.1 - 0.21 10.3 2.0 0.29 9.9 2.0 1.2 1 0 0 1 1 1 0 MCRA family Flocculin_t3 PF13928.6 EMG48233.1 - 0.3 11.6 64.0 0.43 11.1 7.8 5.8 2 2 2 4 4 4 0 Flocculin type 3 repeat OST_IS PF18246.1 EMG48236.1 - 0.049 13.9 0.2 0.053 13.8 0.2 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase Insert domain MKT1_C PF12246.8 EMG48237.1 - 8e-61 205.3 4.2 1.5e-60 204.4 3.9 1.6 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EMG48237.1 - 3e-28 98.0 1.0 1.5e-27 95.8 1.0 2.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EMG48237.1 - 2.3e-13 50.5 1.9 9.1e-13 48.6 0.0 2.9 4 0 0 4 4 4 1 XPG N-terminal domain XPG_I PF00867.18 EMG48237.1 - 2e-05 24.8 0.2 6.9e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 XPG I-region Gpi16 PF04113.14 EMG48238.1 - 1.5e-176 588.2 0.1 1.8e-176 588.0 0.1 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Adeno_E4 PF05385.11 EMG48238.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein Elong_Iki1 PF10483.9 EMG48239.1 - 3.7e-77 259.8 3.0 4.2e-77 259.6 3.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DDE_3 PF13358.6 EMG48239.1 - 0.00015 21.6 0.5 0.12 12.1 0.2 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HEAT_EZ PF13513.6 EMG48240.1 - 5.6e-11 42.7 0.1 0.043 14.3 0.0 6.2 6 0 0 6 6 6 3 HEAT-like repeat HEAT PF02985.22 EMG48240.1 - 1.1e-10 40.8 3.8 0.44 10.9 0.0 8.3 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 EMG48240.1 - 2.4e-09 37.4 4.0 1.5 9.2 0.0 7.3 4 2 2 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EMG48240.1 - 1.6e-08 35.0 7.8 3.5 8.3 0.0 7.7 6 2 1 7 7 7 2 Vacuolar 14 Fab1-binding region SF3b1 PF08920.10 EMG48240.1 - 4.3e-05 24.0 2.0 0.00018 22.0 1.9 2.0 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 MMS19_C PF12460.8 EMG48240.1 - 0.00066 18.9 11.8 0.045 12.9 0.0 5.3 4 1 0 5 5 5 1 RNAPII transcription regulator C-terminal Tti2 PF10521.9 EMG48240.1 - 0.013 15.0 1.4 4.4 6.8 0.0 3.1 3 0 0 3 3 3 0 Tti2 family Cnd1 PF12717.7 EMG48240.1 - 0.22 11.6 18.2 14 5.6 0.2 6.2 6 1 1 7 7 7 0 non-SMC mitotic condensation complex subunit 1 DUF1981 PF09324.10 EMG48240.1 - 1.7 8.5 4.5 16 5.4 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) Glyco_hydro_65m PF03632.15 EMG48240.1 - 2.6 6.8 5.3 4.4 6.0 5.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain RED_C PF07807.11 EMG48241.1 - 0.0051 17.3 0.1 0.013 16.0 0.1 1.6 1 0 0 1 1 1 1 RED-like protein C-terminal region Cut8 PF08559.10 EMG48241.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein MAGE PF01454.19 EMG48242.1 - 1.4e-38 132.8 0.4 1.8e-38 132.4 0.4 1.1 1 0 0 1 1 1 1 MAGE family Androgen_recep PF02166.16 EMG48242.1 - 4.9 5.9 7.0 6.6 5.4 7.0 1.1 1 0 0 1 1 1 0 Androgen receptor FAD_binding_1 PF00667.20 EMG48243.1 - 2.3e-80 269.3 0.0 3.4e-80 268.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EMG48243.1 - 1.6e-34 119.2 0.5 2.9e-34 118.3 0.5 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EMG48243.1 - 4.4e-24 85.2 0.0 2.2e-23 83.0 0.0 2.2 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Ins_P5_2-kin PF06090.12 EMG48244.1 - 8.4e-27 94.5 4.1 3.4e-26 92.5 4.1 1.8 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase AIM24 PF01987.17 EMG48244.1 - 3.3e-09 36.8 0.0 5.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PhoLip_ATPase_C PF16212.5 EMG48246.1 - 9.8e-06 25.5 4.9 1.3e-05 25.1 4.9 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Mad3_BUB1_I PF08311.12 EMG48247.1 - 6.7e-45 152.1 2.1 1.5e-44 150.9 2.1 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 EMG48247.1 - 1.8e-16 60.1 4.5 4e-16 58.9 0.1 3.5 4 0 0 4 4 4 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 EMG48247.1 - 1.9e-16 60.3 0.0 3.5e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Mad3_BUB1_I_2 PF17014.5 EMG48247.1 - 2.2e-07 31.0 0.6 5.8e-07 29.7 0.6 1.7 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Pkinase_Tyr PF07714.17 EMG48247.1 - 0.0017 17.7 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_14 PF17959.1 EMG48247.1 - 0.44 10.9 2.3 4.5 7.7 0.0 3.5 3 1 1 4 4 4 0 EF-hand domain PhoLip_ATPase_C PF16212.5 EMG48248.1 - 1.9e-32 113.0 7.7 1.9e-32 113.0 7.7 3.0 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMG48248.1 - 3.4e-24 84.3 5.8 3.7e-23 81.0 0.6 2.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EMG48248.1 - 1.6e-14 54.7 1.2 7.9e-07 29.6 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMG48248.1 - 9.6e-13 48.0 0.0 5.4e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EMG48248.1 - 3.1e-09 36.6 0.0 1e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EMG48248.1 - 0.0018 18.1 5.6 0.0019 18.0 0.1 3.6 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Phytase PF02333.15 EMG48248.1 - 0.092 11.7 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Phytase HAD_2 PF13419.6 EMG48248.1 - 0.14 12.2 4.0 0.13 12.3 0.1 2.7 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase AA_permease PF00324.21 EMG48249.1 - 6.9e-15 54.6 4.8 8.3e-15 54.3 4.8 1.0 1 0 0 1 1 1 1 Amino acid permease Ribonuclease_T2 PF00445.18 EMG48250.1 - 3.1e-32 112.3 3.3 4.2e-32 111.8 3.3 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Intron_maturas2 PF01348.21 EMG48250.1 - 0.12 12.4 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Type II intron maturase Mso1_Sec1_bdg PF14475.6 EMG48252.1 - 2 8.1 12.0 1.5 8.5 0.4 3.6 3 0 0 3 3 3 0 Sec1-binding region of Mso1 TMF_DNA_bd PF12329.8 EMG48253.1 - 0.00099 19.1 10.7 0.00099 19.1 10.7 8.3 2 2 6 8 8 8 3 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 EMG48253.1 - 4.1 6.2 85.6 0.2 10.5 24.1 5.0 1 1 4 5 5 5 0 Spc7 kinetochore protein TFIIA PF03153.13 EMG48254.1 - 6.1e-34 118.7 27.4 1.6e-19 71.2 3.7 2.2 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 EMG48254.1 - 7.3 5.8 12.0 11 5.3 12.0 1.3 1 0 0 1 1 1 0 BUD22 He_PIG PF05345.12 EMG48255.1 - 9.5e-17 60.9 16.9 1.2e-08 35.0 2.2 5.1 4 0 0 4 4 4 3 Putative Ig domain Mid2 PF04478.12 EMG48255.1 - 2.5e-07 30.6 0.4 1.3e-06 28.3 0.4 2.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 EMG48255.1 - 1.7e-06 27.3 0.2 6.7e-06 25.4 0.2 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 EMG48255.1 - 3.4e-06 27.0 0.7 3.4e-06 27.0 0.7 2.8 3 1 0 3 3 2 1 TMEM154 protein family DUF4448 PF14610.6 EMG48255.1 - 0.00071 19.4 0.2 0.003 17.4 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DAG1 PF05454.11 EMG48255.1 - 0.0062 16.0 0.1 0.013 14.8 0.1 1.5 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) MLANA PF14991.6 EMG48255.1 - 0.0079 16.5 0.6 0.024 14.9 0.2 2.1 1 1 1 2 2 2 1 Protein melan-A MGC-24 PF05283.11 EMG48255.1 - 0.019 15.4 6.8 0.019 15.4 6.8 2.9 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Orf78 PF06024.12 EMG48255.1 - 0.019 15.3 0.0 0.096 13.0 0.0 2.2 1 0 0 1 1 1 0 Orf78 (ac78) ETRAMP PF09716.10 EMG48255.1 - 0.063 13.3 0.2 0.2 11.7 0.2 1.9 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) EphA2_TM PF14575.6 EMG48255.1 - 0.078 13.9 0.0 0.21 12.5 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Comm PF15957.5 EMG48255.1 - 0.08 13.3 0.2 0.97 9.8 0.0 2.9 3 1 0 3 3 2 0 Commissureless TMIE PF16038.5 EMG48255.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 TMIE protein Podoplanin PF05808.11 EMG48255.1 - 0.15 12.2 8.1 0.11 12.6 1.8 2.9 2 1 0 2 2 2 0 Podoplanin RIFIN PF02009.16 EMG48255.1 - 0.6 9.9 3.9 0.43 10.4 0.2 2.1 2 0 0 2 2 2 0 Rifin Shisa PF13908.6 EMG48255.1 - 0.66 10.2 12.9 0.055 13.7 1.8 2.6 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Herpes_pp85 PF04637.12 EMG48255.1 - 1.1 7.6 13.5 1.9 6.8 13.5 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) MMU163 PF17119.5 EMG48255.1 - 2.9 7.0 10.4 0.17 11.0 0.6 2.4 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis 4HBT PF03061.22 EMG48256.1 - 9.5e-05 22.7 0.1 0.19 12.1 0.0 2.8 2 1 0 2 2 2 2 Thioesterase superfamily Transket_pyr PF02779.24 EMG48257.1 - 2e-44 151.4 0.0 3.1e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMG48257.1 - 2.3e-38 130.9 0.0 6.7e-38 129.4 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain FAD_binding_8 PF08022.12 EMG48258.1 - 2.2e-24 85.6 0.0 3.9e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EMG48258.1 - 2.2e-21 76.3 10.4 2.2e-21 76.3 10.4 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component CitMHS PF03600.16 EMG48258.1 - 0.94 8.6 4.4 1.5 7.9 4.4 1.3 1 0 0 1 1 1 0 Citrate transporter DAGK_cat PF00781.24 EMG48260.1 - 7.5e-10 38.5 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF5599 PF18141.1 EMG48260.1 - 0.002 18.3 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) DUF4159 PF13709.6 EMG48260.1 - 0.088 12.2 0.0 5.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4159) XRN_M PF17846.1 EMG48261.1 - 1.1e-135 453.0 5.0 1.1e-135 453.0 5.0 3.0 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 EMG48261.1 - 2.8e-99 331.5 0.0 2.8e-99 331.5 0.0 2.5 4 0 0 4 4 4 1 XRN 5'-3' exonuclease N-terminus DUF1635 PF07795.11 EMG48261.1 - 0.8 9.5 5.9 1.8 8.3 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) AA_permease PF00324.21 EMG48262.1 - 5.5e-18 64.8 7.5 6.3e-18 64.6 7.5 1.0 1 0 0 1 1 1 1 Amino acid permease DASH_Ask1 PF08655.10 EMG48264.1 - 3.3e-29 100.6 0.9 1.2e-28 98.8 0.5 2.0 2 0 0 2 2 2 1 DASH complex subunit Ask1 SBF2 PF12335.8 EMG48264.1 - 0.59 9.7 5.7 0.067 12.8 0.9 1.8 2 0 0 2 2 2 0 Myotubularin protein UPF0203 PF05254.12 EMG48265.1 - 9e-27 93.1 0.9 1.1e-26 92.8 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 EMG48265.1 - 0.00027 20.9 0.5 0.091 12.8 0.1 2.4 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 EMG48265.1 - 0.003 17.7 0.1 0.0049 17.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 EMG48265.1 - 0.021 15.2 0.1 0.055 13.8 0.1 1.6 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Lipase_3 PF01764.25 EMG48266.1 - 5.1e-16 58.8 0.0 9.4e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) zf-HIT PF04438.16 EMG48266.1 - 0.97 9.4 15.1 0.15 12.0 10.3 2.0 2 0 0 2 2 2 0 HIT zinc finger Pyr_redox_2 PF07992.14 EMG48267.1 - 3.8e-10 39.5 0.0 7.5e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMG48267.1 - 0.00022 21.2 0.0 0.0011 19.0 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMG48267.1 - 0.028 14.6 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Aminotran_1_2 PF00155.21 EMG48268.1 - 6e-64 216.5 0.0 6.8e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2 PF00096.26 EMG48269.1 - 1.7e-09 37.6 11.3 9.1e-06 25.9 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG48269.1 - 1.8e-08 34.5 10.5 0.00042 20.9 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EMG48269.1 - 4e-08 33.4 4.2 0.0056 17.0 0.2 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EMG48269.1 - 8.5e-07 29.1 17.1 1.4e-06 28.5 4.8 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EMG48269.1 - 4.9e-05 23.5 9.4 0.08 13.3 2.2 3.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EMG48269.1 - 0.0046 16.9 12.6 0.0062 16.5 1.7 3.0 2 1 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 EMG48269.1 - 0.02 15.2 4.9 0.046 14.0 4.9 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 EMG48269.1 - 0.07 13.6 19.9 0.079 13.4 2.5 3.3 2 2 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 EMG48269.1 - 0.11 12.9 0.4 0.11 12.9 0.4 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1595 PF12760.7 EMG48269.1 - 0.15 12.1 4.2 0.29 11.2 4.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 EMG48269.1 - 0.16 12.1 1.8 13 6.0 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-LYAR PF08790.11 EMG48269.1 - 0.21 11.5 3.7 0.37 10.7 0.2 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Elf1 PF05129.13 EMG48269.1 - 0.37 10.9 8.8 1.6 8.8 8.8 2.1 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-BED PF02892.15 EMG48269.1 - 0.83 9.7 7.2 13 5.9 7.2 2.6 1 1 0 1 1 1 0 BED zinc finger Actin_micro PF17003.5 EMG48269.1 - 4.7 6.3 7.0 14 4.8 0.7 2.3 1 1 1 2 2 2 0 Putative actin-like family SRF-TF PF00319.18 EMG48270.1 - 2.5e-21 74.9 0.1 3.9e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ribosomal_S6e PF01092.19 EMG48271.1 - 6.9e-61 203.8 0.2 1.4e-60 202.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e VKG_Carbox PF05090.14 EMG48271.1 - 0.075 11.9 0.5 0.092 11.6 0.5 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase DUF2543 PF10820.8 EMG48271.1 - 0.089 13.0 0.4 0.18 12.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) DUF4574 PF15141.6 EMG48271.1 - 0.74 9.8 5.5 1.3 9.0 5.5 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 PRP21_like_P PF12230.8 EMG48272.1 - 8.7e-55 185.9 9.3 1.3e-54 185.3 9.3 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EMG48272.1 - 3.4e-29 100.6 1.5 1e-14 54.2 0.1 2.6 2 0 0 2 2 2 2 Surp module zinc_ribbon_6 PF14599.6 EMG48273.1 - 6.6e-23 80.5 1.2 6.6e-23 80.5 1.2 4.6 4 2 3 7 7 7 1 Zinc-ribbon zf-CHY PF05495.12 EMG48273.1 - 6.6e-17 61.8 23.9 6.6e-17 61.8 23.9 4.0 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EMG48273.1 - 1.4e-07 31.7 11.6 1.4e-07 31.7 11.6 5.4 3 1 3 6 6 6 1 Ring finger domain zf-C3HC4_3 PF13920.6 EMG48273.1 - 7.5e-06 25.7 9.8 7.5e-06 25.7 9.8 5.9 4 1 2 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMG48273.1 - 0.00032 20.6 12.8 0.00032 20.6 12.8 5.7 5 1 1 6 6 6 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMG48273.1 - 0.0029 17.6 4.5 0.0029 17.6 4.5 5.3 4 2 1 5 5 5 1 RING-type zinc-finger DZR PF12773.7 EMG48273.1 - 0.019 15.0 12.2 0.019 15.0 12.2 4.9 3 1 0 3 3 3 0 Double zinc ribbon NIF PF03031.18 EMG48274.1 - 6.1e-47 159.3 1.3 7.9e-46 155.7 1.1 2.5 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase Ashwin PF15323.6 EMG48274.1 - 0.082 12.9 3.3 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 Developmental protein DUF913 PF06025.12 EMG48274.1 - 0.094 11.7 1.1 0.14 11.1 1.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spore_coat_CotO PF14153.6 EMG48274.1 - 0.1 12.5 16.4 0.25 11.2 16.4 1.6 1 0 0 1 1 1 0 Spore coat protein CotO SUIM_assoc PF16619.5 EMG48274.1 - 0.2 11.8 5.6 0.49 10.5 5.6 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PIN_6 PF17146.4 EMG48274.1 - 0.31 11.6 2.4 0.61 10.6 1.2 2.2 2 0 0 2 2 2 0 PIN domain of ribonuclease FYDLN_acid PF09538.10 EMG48274.1 - 3.6 8.3 10.4 8.7 7.1 10.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Acetyltransf_1 PF00583.25 EMG48277.1 - 6.6e-08 32.8 0.0 1.9e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMG48277.1 - 1.2e-07 32.0 0.0 2.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMG48277.1 - 9.1e-06 25.6 0.0 0.00011 22.2 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMG48277.1 - 0.061 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SAS-6_N PF16531.5 EMG48277.1 - 0.082 13.5 1.2 0.17 12.5 1.2 1.5 1 0 0 1 1 1 0 Centriolar protein SAS N-terminal DUF2384 PF09722.10 EMG48277.1 - 0.086 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) PT-HINT PF07591.11 EMG48278.1 - 0.0098 16.1 1.5 0.012 15.8 1.5 1.2 1 0 0 1 1 1 1 Pretoxin HINT domain Microtub_bd PF16796.5 EMG48278.1 - 0.039 13.9 1.2 0.047 13.6 1.2 1.2 1 0 0 1 1 1 0 Microtubule binding Mucin PF01456.17 EMG48278.1 - 0.36 10.8 16.1 0.72 9.8 16.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein ALS_ss_C PF10369.9 EMG48279.1 - 9.3e-16 57.8 0.0 4.5e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EMG48279.1 - 2.2e-13 49.7 0.1 4.5e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EMG48279.1 - 7.8e-06 25.6 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain Zn_clus PF00172.18 EMG48280.1 - 2.1e-08 34.1 11.5 3.8e-08 33.3 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 EMG48282.1 - 7.5e-87 292.2 0.0 1e-86 291.7 0.0 1.2 1 0 0 1 1 1 1 Amidase OPT PF03169.15 EMG48283.1 - 2.1e-156 522.2 40.2 2.4e-156 522.0 40.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein YtzH PF14165.6 EMG48283.1 - 0.21 12.0 0.5 0.63 10.5 0.0 1.9 2 0 0 2 2 2 0 YtzH-like protein TMEM154 PF15102.6 EMG48284.1 - 0.005 16.7 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family SR-25 PF10500.9 EMG48285.1 - 0.1 12.2 18.5 0.5 10.0 5.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EMG48285.1 - 1.6 9.4 13.1 0.096 13.4 4.3 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein SH3_1 PF00018.28 EMG48286.1 - 3.1e-23 81.1 0.4 2.1e-11 43.3 0.3 3.1 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EMG48286.1 - 2.3e-13 49.8 0.1 2.2e-08 33.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 EMG48286.1 - 5.5e-13 48.9 0.0 1.5e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EMG48286.1 - 1.4e-08 34.2 0.0 3.7e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain CBFD_NFYB_HMF PF00808.23 EMG48287.1 - 5.5e-21 74.6 0.1 9.4e-21 73.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMG48287.1 - 0.011 16.1 0.7 0.027 14.8 0.0 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EMG48287.1 - 0.034 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit NMT_C PF02799.15 EMG48290.1 - 4.6e-81 271.3 0.4 6.6e-81 270.8 0.4 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EMG48290.1 - 6.7e-73 243.8 0.0 1.1e-72 243.1 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 EMG48290.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Candida_ALS_N PF11766.8 EMG48293.1 - 2.8e-86 288.8 7.5 4.7e-86 288.1 7.5 1.3 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Candida_ALS PF05792.13 EMG48293.1 - 0.0012 19.3 21.2 0.0012 19.3 21.2 5.1 6 0 0 6 6 6 1 Candida agglutinin-like (ALS) F-box-like PF12937.7 EMG48295.1 - 0.0004 20.2 0.3 0.00085 19.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like MIT PF04212.18 EMG48295.1 - 0.006 16.6 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Thioredoxin_4 PF13462.6 EMG48296.1 - 2.7e-07 30.9 0.1 1.4e-06 28.6 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin WD40 PF00400.32 EMG48297.1 - 2.7e-09 37.5 11.4 0.0039 18.0 1.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 EMG48297.1 - 7.2e-05 21.6 0.9 0.00014 20.7 0.9 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EMG48297.1 - 0.0016 18.7 0.5 2.1 8.7 0.4 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EMG48297.1 - 0.035 14.6 0.0 0.22 12.1 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain WD40_like PF17005.5 EMG48297.1 - 0.066 12.5 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 WD40-like domain RNA_polI_A34 PF08208.11 EMG48297.1 - 1.5 8.9 9.0 0.7 9.9 2.3 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 MRP-S26 PF14943.6 EMG48297.1 - 3.7 7.4 15.6 0.7 9.8 11.3 1.8 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Tristanin_u2 PF16638.5 EMG48297.1 - 7.9 7.3 9.4 6.5 7.6 6.2 2.2 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers DUF89 PF01937.19 EMG48298.1 - 1.6e-115 385.8 2.8 1.9e-115 385.6 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 eIF-3c_N PF05470.12 EMG48299.1 - 1.2e-141 473.1 17.6 3.1e-112 375.9 2.1 3.3 3 1 1 4 4 4 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EMG48299.1 - 1.5e-08 35.1 0.6 1.3e-07 32.1 0.1 2.9 3 0 0 3 3 3 1 PCI domain ALMT PF11744.8 EMG48299.1 - 0.071 11.9 17.5 0.16 10.8 12.5 2.7 2 0 0 2 2 2 0 Aluminium activated malate transporter Pex14_N PF04695.13 EMG48299.1 - 0.61 10.7 23.9 2 9.0 23.9 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Band_3_cyto PF07565.13 EMG48299.1 - 1.6 8.5 12.9 2.3 7.9 11.1 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Candida_ALS PF05792.13 EMG48300.1 - 2.8e-10 40.6 41.3 1.1e-08 35.5 18.0 9.7 8 3 0 8 8 8 2 Candida agglutinin-like (ALS) TAP42 PF04177.12 EMG48301.1 - 8.2e-81 271.6 4.7 9.4e-81 271.4 4.7 1.0 1 0 0 1 1 1 1 TAP42-like family Nup160 PF11715.8 EMG48302.1 - 2.6e-46 158.4 10.1 4e-46 157.8 10.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Cactin_mid PF10312.9 EMG48302.1 - 0.0022 17.8 2.9 0.087 12.5 0.3 2.5 2 0 0 2 2 2 2 Conserved mid region of cactin DWNN PF08783.11 EMG48303.1 - 2.1e-25 88.8 0.2 2.1e-25 88.8 0.2 2.1 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 EMG48303.1 - 1.9e-08 33.9 8.1 4.4e-08 32.8 8.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EMG48303.1 - 0.00024 21.0 1.7 0.00024 21.0 1.7 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 EMG48303.1 - 0.0046 16.6 4.6 0.011 15.4 0.7 2.9 3 0 0 3 3 3 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 EMG48303.1 - 0.033 14.1 0.1 0.098 12.6 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF1610 PF07754.11 EMG48303.1 - 0.047 13.7 0.2 0.13 12.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Bul1_N PF04425.12 EMG48304.1 - 9.3e-148 492.7 5.2 9.3e-148 492.7 5.2 2.2 1 1 1 2 2 2 1 Bul1 N terminus GATase PF00117.28 EMG48304.1 - 5.1e-46 156.8 0.0 9.3e-46 156.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EMG48304.1 - 5e-45 152.5 0.0 1.5e-44 150.9 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Bul1_C PF04426.12 EMG48304.1 - 4.3e-11 42.7 7.7 3e-07 30.1 1.3 3.0 2 1 1 3 3 3 2 Bul1 C terminus Peptidase_C26 PF07722.13 EMG48304.1 - 0.00061 19.6 0.6 0.0084 15.9 0.6 2.4 1 1 0 1 1 1 1 Peptidase C26 DUF1870 PF08965.10 EMG48304.1 - 0.66 10.0 3.7 0.6 10.1 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) FA_hydroxylase PF04116.13 EMG48305.1 - 1.7e-26 93.1 19.1 1.7e-26 93.1 19.1 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L18A PF01775.17 EMG48306.1 - 7.6e-54 181.0 1.0 1.1e-53 180.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A adh_short PF00106.25 EMG48307.1 - 4.8e-43 146.9 0.0 6.3e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG48307.1 - 5.2e-30 104.7 0.0 6.8e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG48307.1 - 5.8e-10 39.4 0.0 8.8e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMG48307.1 - 0.0011 18.2 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMG48307.1 - 0.0018 17.8 0.0 0.0056 16.2 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family LIX1 PF14954.6 EMG48307.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Limb expression 1 DUF1776 PF08643.10 EMG48307.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) ATP_bind_3 PF01171.20 EMG48308.1 - 2.4e-18 66.6 0.0 5.9e-18 65.3 0.0 1.7 1 1 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 EMG48308.1 - 1e-16 60.1 4.8 1e-16 60.1 4.8 3.6 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 EMG48308.1 - 0.028 13.2 0.0 0.096 11.5 0.0 1.9 1 1 0 1 1 1 0 tRNA methyl transferase Cytochrom_c3_2 PF14537.6 EMG48308.1 - 2.9 8.4 8.7 1.4 9.5 0.3 2.5 2 0 0 2 2 2 0 Cytochrome c3 CUE PF02845.16 EMG48309.1 - 4e-07 29.6 0.4 7.7e-07 28.7 0.4 1.5 1 0 0 1 1 1 1 CUE domain HMG_box PF00505.19 EMG48310.1 - 4.6e-26 91.0 0.8 4.6e-26 91.0 0.8 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMG48310.1 - 2.9e-18 66.2 0.5 4.6e-18 65.6 0.5 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EMG48310.1 - 0.0012 19.4 0.0 0.0012 19.4 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 EMG48310.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 CHDNT (NUC034) domain F_bP_aldolase PF01116.20 EMG48311.1 - 6.8e-92 307.9 0.0 7.7e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II zf-Tim10_DDP PF02953.15 EMG48312.1 - 1.5e-15 56.6 0.2 1.9e-15 56.3 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TTL PF03133.15 EMG48313.1 - 3.2e-59 200.5 0.4 5.1e-59 199.8 0.4 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EMG48313.1 - 8.4e-45 153.0 0.0 1.3e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EMG48313.1 - 0.003 16.9 0.1 0.032 13.5 0.1 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp BSD PF03909.17 EMG48314.1 - 2.7e-19 68.9 1.9 1.2e-11 44.5 0.0 2.8 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 EMG48314.1 - 2.2e-17 63.1 0.0 6.1e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain SIN1_PH PF16979.5 EMG48314.1 - 0.033 14.5 0.1 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology SR-25 PF10500.9 EMG48314.1 - 4.1 6.9 10.1 4.7 6.8 5.0 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Acetyltransf_1 PF00583.25 EMG48315.1 - 1.3e-15 57.7 0.0 1.7e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMG48315.1 - 1e-08 35.4 0.0 1.5e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMG48315.1 - 3.1e-08 33.6 0.0 4.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMG48315.1 - 3.4e-07 31.0 0.0 4.3e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMG48315.1 - 7.3e-06 25.9 0.1 1.2e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EMG48315.1 - 9.4e-05 22.1 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMG48315.1 - 0.0024 18.0 0.2 0.0028 17.8 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EMG48315.1 - 0.0065 16.0 2.7 0.096 12.1 0.3 2.3 1 1 1 2 2 2 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 EMG48315.1 - 0.0095 16.0 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMG48315.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 EMG48315.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Coa1 PF08695.10 EMG48316.1 - 2e-41 140.4 0.0 2.7e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Thioredoxin_8 PF13905.6 EMG48317.1 - 0.0069 16.7 3.5 0.072 13.4 0.1 3.0 2 1 1 3 3 3 1 Thioredoxin-like Ac76 PF05814.11 EMG48317.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) Prenyltrans PF00432.21 EMG48318.1 - 1.1e-29 101.8 1.2 6e-06 25.9 0.0 5.5 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat GLYCAM-1 PF05242.11 EMG48318.1 - 0.026 14.6 1.9 0.042 14.0 1.9 1.3 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) DUF2418 PF10332.9 EMG48320.1 - 1.1e-27 96.4 2.9 1.1e-27 96.4 2.9 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2418) Nup35_RRM PF05172.13 EMG48321.1 - 7.5e-22 77.2 0.3 1.9e-21 75.9 0.3 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EMG48321.1 - 1.8e-06 27.9 0.0 4.2e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RNA_pol_Rpb2_4 PF04566.13 EMG48321.1 - 0.03 14.6 0.2 0.071 13.4 0.2 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 TFIIA PF03153.13 EMG48321.1 - 0.25 11.3 30.0 0.021 14.9 24.3 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 EMG48322.1 - 5.9e-36 123.8 5.0 5.9e-36 123.8 5.0 2.2 2 0 0 2 2 2 1 RXT2-like, N-terminal PCNA_C PF02747.15 EMG48323.1 - 4.3e-42 143.3 0.1 8e-42 142.4 0.1 1.4 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 EMG48323.1 - 2.2e-36 124.3 2.0 3e-33 114.2 0.5 3.0 2 1 1 3 3 3 2 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 EMG48323.1 - 5.8e-07 28.9 2.3 4.2e-05 22.8 1.7 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EMG48323.1 - 0.0026 17.2 0.2 0.0033 16.9 0.2 1.2 1 0 0 1 1 1 1 Rad9 Calreticulin PF00262.18 EMG48324.1 - 6.6e-105 351.0 7.3 4.1e-79 266.1 0.1 2.3 1 1 1 2 2 2 2 Calreticulin family Alb1 PF09135.11 EMG48325.1 - 8.9e-21 74.7 13.9 8.9e-21 74.7 13.9 1.9 2 0 0 2 2 2 1 Alb1 Prominin PF05478.11 EMG48325.1 - 0.35 8.8 5.0 0.38 8.7 5.0 1.0 1 0 0 1 1 1 0 Prominin Hydrolase_4 PF12146.8 EMG48328.1 - 3.7e-08 32.9 0.0 5e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 EMG48328.1 - 0.00039 20.4 0.0 0.00055 19.9 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 EMG48328.1 - 0.0034 17.1 0.5 0.011 15.4 0.3 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold bZIP_2 PF07716.15 EMG48329.1 - 6.3e-10 39.0 6.0 6.3e-10 39.0 6.0 2.3 2 0 0 2 2 2 1 Basic region leucine zipper Uds1 PF15456.6 EMG48329.1 - 0.0062 16.7 4.1 0.016 15.3 4.1 1.7 1 0 0 1 1 1 1 Up-regulated During Septation SR-25 PF10500.9 EMG48329.1 - 0.013 15.2 6.0 0.023 14.3 6.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TSC22 PF01166.18 EMG48329.1 - 0.23 11.8 5.3 0.47 10.8 4.0 2.3 1 1 0 1 1 1 0 TSC-22/dip/bun family YabA PF06156.13 EMG48329.1 - 0.53 11.0 7.8 0.83 10.3 5.9 2.2 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 EMG48329.1 - 0.69 10.1 14.5 0.038 14.1 9.0 1.8 2 0 0 2 2 2 0 bZIP transcription factor Exo_endo_phos PF03372.23 EMG48330.1 - 2.6e-10 40.2 0.1 6e-10 39.0 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Flocculin_t3 PF13928.6 EMG48331.1 - 0.0094 16.4 7.4 0.0094 16.4 7.4 3.5 1 1 1 2 2 2 1 Flocculin type 3 repeat PT PF04886.12 EMG48332.1 - 9.7e-08 31.4 21.9 9.7e-08 31.4 21.9 2.7 2 1 1 3 3 3 1 PT repeat DUF2283 PF10049.9 EMG48332.1 - 0.0012 19.0 0.3 0.006 16.8 0.3 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2283) CT47 PF15623.6 EMG48332.1 - 0.0082 16.0 21.8 0.013 15.3 21.8 1.3 1 0 0 1 1 1 1 Cancer/testis gene family 47 Lin-8 PF03353.15 EMG48332.1 - 0.37 10.3 4.7 0.44 10.0 4.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4106 PF13388.6 EMG48332.1 - 0.54 9.4 2.9 0.78 8.9 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Pneumo_att_G PF05539.11 EMG48332.1 - 1.3 8.6 6.8 1.7 8.1 6.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G FGF-BP1 PF06473.12 EMG48332.1 - 3 7.6 5.0 3.7 7.3 5.0 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) CAF1A PF12253.8 EMG48333.1 - 6.2e-23 80.8 10.6 6.2e-23 80.8 10.6 4.4 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Caldesmon PF02029.15 EMG48333.1 - 0.0045 15.8 60.5 0.0052 15.6 52.8 2.1 2 0 0 2 2 2 2 Caldesmon DUF4670 PF15709.5 EMG48333.1 - 0.055 12.8 59.0 0.1 11.9 59.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Mucin PF01456.17 EMG48333.1 - 0.99 9.4 13.7 2.5 8.1 13.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein CPSase_L_D2 PF02786.17 EMG48334.1 - 1.7e-79 266.2 0.1 2.6e-79 265.6 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EMG48334.1 - 4.8e-66 222.3 0.0 8.4e-66 221.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EMG48334.1 - 3.4e-39 133.8 0.0 7e-39 132.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EMG48334.1 - 2.3e-30 104.9 0.0 5e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EMG48334.1 - 2.9e-22 79.5 0.0 6.3e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EMG48334.1 - 5.6e-16 58.1 1.2 5.6e-16 58.1 1.2 2.7 3 0 0 3 3 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EMG48334.1 - 8.9e-07 28.6 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EMG48334.1 - 3.6e-06 26.6 0.0 7.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EMG48334.1 - 1.3e-05 25.0 0.0 0.051 13.4 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EMG48334.1 - 0.00014 22.0 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EMG48334.1 - 0.0042 16.4 0.0 0.017 14.3 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 EMG48334.1 - 0.02 14.5 0.0 0.092 12.3 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain GCV_H PF01597.19 EMG48334.1 - 0.055 13.3 2.6 5.2 7.0 0.2 3.0 2 1 1 3 3 2 0 Glycine cleavage H-protein HlyD_D23 PF16576.5 EMG48334.1 - 0.058 12.6 0.1 2 7.6 0.1 2.5 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion PYNP_C PF07831.13 EMG48334.1 - 0.073 12.7 1.1 1.4 8.7 0.0 2.8 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain RnfC_N PF13375.6 EMG48334.1 - 1.4 8.9 4.5 2.9 7.9 0.7 3.4 4 1 0 4 4 4 0 RnfC Barrel sandwich hybrid domain T4SS PF07996.11 EMG48335.1 - 0.14 12.6 0.0 19 5.6 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion system proteins GCR1_C PF12550.8 EMG48336.1 - 4.3e-13 49.4 2.9 2e-12 47.3 2.9 2.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TFIIF_alpha PF05793.12 EMG48336.1 - 1.1 7.8 19.3 0.074 11.6 13.8 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FCP1_C PF09309.10 EMG48336.1 - 7.1 6.4 15.6 2 8.2 6.5 2.7 1 1 1 2 2 2 0 FCP1, C-terminal LRR_8 PF13855.6 EMG48337.1 - 2.3e-11 43.3 33.8 3.3e-07 30.0 0.4 7.4 6 1 1 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 EMG48337.1 - 1.6e-08 34.7 50.4 0.0048 17.3 0.0 10.2 6 3 4 10 10 10 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMG48337.1 - 2.2e-06 27.2 16.4 5.2 7.4 0.1 8.1 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 EMG48337.1 - 0.00031 20.9 22.7 3 8.7 0.0 8.6 6 2 0 6 6 6 2 Leucine Rich Repeat F-box PF00646.33 EMG48337.1 - 0.054 13.4 0.2 0.22 11.4 0.2 2.2 1 0 0 1 1 1 0 F-box domain FNIP PF05725.12 EMG48337.1 - 1.4 9.1 27.1 10 6.4 0.1 8.9 9 2 1 10 10 10 0 FNIP Repeat Sugar_tr PF00083.24 EMG48338.1 - 6.7e-45 153.8 22.3 1.2e-44 152.9 22.3 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG48338.1 - 3.8e-36 124.8 42.2 5.9e-30 104.4 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 EMG48338.1 - 0.095 12.2 2.5 3.5 7.1 0.0 2.8 3 0 0 3 3 3 0 E1-E2 ATPase ATG11 PF10377.9 EMG48339.1 - 7e-41 139.3 0.5 7e-41 139.3 0.5 3.6 3 1 1 4 4 4 1 Autophagy-related protein 11 ACP_PD PF04336.12 EMG48339.1 - 3 8.3 7.7 1.4 9.4 0.0 4.2 4 0 0 4 4 4 0 Acyl carrier protein phosphodiesterase RNase_PH PF01138.21 EMG48340.1 - 1e-09 39.0 0.0 1.8e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EMG48340.1 - 4.1e-07 29.9 0.7 1.1e-06 28.6 0.0 2.1 3 0 0 3 3 3 1 3' exoribonuclease family, domain 2 N_Asn_amidohyd PF14736.6 EMG48340.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase SpoU_methylase PF00588.19 EMG48341.1 - 4.2e-26 91.8 0.0 9.5e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family Condensin2nSMC PF12422.8 EMG48341.1 - 1.9 8.6 6.1 3.5 7.8 0.1 3.8 4 0 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit DUF3445 PF11927.8 EMG48342.1 - 4.5e-72 242.3 0.0 5.5e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PX PF00787.24 EMG48343.1 - 3.6e-18 65.6 3.5 7e-18 64.7 0.2 2.9 2 0 0 2 2 2 1 PX domain JHD PF17811.1 EMG48343.1 - 0.064 13.8 3.5 0.58 10.7 0.1 3.3 2 1 1 3 3 3 0 Jumonji helical domain DUF3446 PF11928.8 EMG48343.1 - 3.2 8.1 14.9 0.45 10.8 0.6 3.1 3 0 0 3 3 3 0 Early growth response N-terminal domain Peptidase_C10 PF01640.17 EMG48343.1 - 3.4 8.0 11.4 0.053 13.8 1.8 2.9 3 0 0 3 3 3 0 Peptidase C10 family Nup84_Nup100 PF04121.13 EMG48344.1 - 4e-181 603.8 15.5 4.6e-181 603.6 15.5 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 RPN6_N PF18055.1 EMG48345.1 - 1.9e-35 121.7 5.6 1.9e-35 121.7 5.6 3.0 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EMG48345.1 - 3.1e-11 43.7 0.7 3.1e-11 43.7 0.7 3.0 2 1 1 3 3 3 1 PCI domain TPR_12 PF13424.6 EMG48345.1 - 0.00013 22.2 4.5 0.007 16.6 0.5 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMG48345.1 - 0.00089 19.2 3.6 0.33 11.2 0.4 4.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMG48345.1 - 0.0011 19.4 2.4 0.07 13.6 0.5 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EMG48345.1 - 0.0024 17.3 1.5 0.0035 16.8 1.5 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_16 PF13432.6 EMG48345.1 - 0.0047 17.6 0.0 0.17 12.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 EMG48345.1 - 0.036 13.8 5.4 0.11 12.1 1.5 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 EMG48345.1 - 0.095 13.6 0.0 8.3 7.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.12 EMG48345.1 - 0.15 12.1 2.8 0.64 10.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF627) ATP13 PF12921.7 EMG48345.1 - 0.72 9.7 6.4 1.2 9.0 0.3 3.0 2 1 0 3 3 3 0 Mitochondrial ATPase expression TPR_6 PF13174.6 EMG48345.1 - 3.4 8.5 7.0 1.2 9.9 0.4 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMG48345.1 - 3.6 8.0 13.0 1.1 9.6 0.7 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 EMG48346.1 - 2e-21 76.5 0.0 4.4e-21 75.4 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG48346.1 - 1e-14 55.0 0.0 2.1e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG48346.1 - 2.5e-14 53.8 0.0 5.2e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG48346.1 - 8.2e-14 52.0 0.0 1.6e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMG48346.1 - 8.2e-12 45.0 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EMG48346.1 - 1.7e-11 44.2 0.0 2.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EMG48346.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.17 EMG48346.1 - 0.05 12.8 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family M20_dimer PF07687.14 EMG48347.1 - 4.2e-09 36.3 0.0 7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain FtsX_ECD PF18075.1 EMG48347.1 - 0.012 16.2 0.4 0.018 15.6 0.4 1.2 1 0 0 1 1 1 0 FtsX extracellular domain YwhD PF08741.10 EMG48347.1 - 0.02 14.6 0.2 0.039 13.7 0.0 1.5 2 0 0 2 2 2 0 YwhD family Ldh_1_C PF02866.18 EMG48348.1 - 3.3e-47 160.5 0.1 6.8e-47 159.5 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EMG48348.1 - 1.5e-45 154.8 0.7 2.5e-45 154.1 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMG48348.1 - 9.6e-05 21.5 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EMG48348.1 - 0.089 13.2 0.1 0.61 10.5 0.0 2.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DUF4574 PF15141.6 EMG48348.1 - 0.091 12.7 0.1 0.62 10.0 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Glyco_hydro_4 PF02056.16 EMG48348.1 - 0.13 11.8 0.8 2.9 7.4 0.2 2.6 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase Arf PF00025.21 EMG48349.1 - 8.2e-76 253.3 0.3 9.3e-76 253.1 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMG48349.1 - 1.9e-17 63.6 0.1 2.6e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EMG48349.1 - 7.8e-13 48.2 0.0 9.2e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EMG48349.1 - 1.5e-12 47.4 0.1 1.7e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EMG48349.1 - 1.3e-11 44.3 0.7 1.5e-07 30.9 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EMG48349.1 - 2e-11 43.7 0.0 2.5e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMG48349.1 - 1.6e-05 24.9 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMG48349.1 - 0.00013 21.5 0.2 0.0013 18.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EMG48349.1 - 0.0018 17.3 1.9 0.026 13.5 0.3 2.5 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EMG48349.1 - 0.0053 17.3 0.3 0.012 16.1 0.3 1.7 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 EMG48349.1 - 0.035 14.6 0.3 0.07 13.7 0.3 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EMG48349.1 - 0.04 13.6 1.4 0.64 9.6 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 EMG48349.1 - 0.049 13.2 1.3 5.8 6.5 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EMG48349.1 - 0.083 12.8 0.1 9.3 6.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 EMG48349.1 - 0.1 12.5 0.3 7.7 6.4 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 EMG48349.1 - 0.15 12.1 0.2 0.33 11.0 0.1 1.6 1 1 1 2 2 2 0 AAA domain PDH PF02153.17 EMG48350.1 - 1.1e-12 47.5 0.0 1.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 EMG48350.1 - 8.6e-06 26.0 0.0 1.7e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EMG48350.1 - 1.3e-05 24.6 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EMG48350.1 - 2.5e-05 24.8 0.1 7.9e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EMG48350.1 - 0.0034 17.0 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EMG48350.1 - 0.0041 17.0 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 EMG48350.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 EMG48350.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain Shikimate_DH PF01488.20 EMG48350.1 - 0.039 14.0 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EMG48350.1 - 0.097 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GHMP_kinases_N PF00288.26 EMG48351.1 - 1.3e-13 51.0 0.1 2.5e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMG48351.1 - 5.4e-09 36.3 0.0 3.4e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal DUF684 PF05075.14 EMG48351.1 - 0.013 14.6 0.0 0.024 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF684) DUF2312 PF10073.9 EMG48351.1 - 0.025 14.2 0.0 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) TPP_enzyme_N PF02776.18 EMG48353.1 - 1.5e-26 93.0 0.1 3.5e-26 91.9 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMG48353.1 - 1.5e-19 70.1 0.0 7.2e-11 42.0 0.0 3.3 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EMG48353.1 - 5.7e-17 61.9 0.7 1.3e-16 60.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EMG48353.1 - 0.034 13.1 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EMG48353.1 - 0.042 13.0 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase PHO4 PF01384.20 EMG48354.1 - 1.5e-118 395.7 16.9 1.8e-118 395.5 16.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family Sulfate_transp PF00916.20 EMG48355.1 - 3.3e-72 243.3 20.5 4.8e-72 242.8 20.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EMG48355.1 - 2.2e-18 66.0 0.3 4.3e-18 65.1 0.3 1.5 1 0 0 1 1 1 1 STAS domain Oxidored-like PF09791.9 EMG48356.1 - 6.2e-25 86.6 2.0 6.2e-25 86.6 2.0 1.6 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal TnsE_C PF18623.1 EMG48356.1 - 0.03 14.3 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 TnsE C-terminal domain ATP-synt_F6 PF05511.11 EMG48356.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DPM3 PF08285.11 EMG48357.1 - 4.4e-30 103.7 0.0 4.9e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2162 PF09930.9 EMG48357.1 - 0.025 14.0 0.0 0.029 13.8 0.0 1.0 1 0 0 1 1 1 0 Predicted transporter (DUF2162) Tau95 PF09734.9 EMG48358.1 - 6.9e-39 133.9 1.9 6.9e-39 133.9 1.9 2.2 3 0 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EMG48358.1 - 1.5e-25 89.8 1.3 1.7e-25 89.6 0.1 1.7 2 0 0 2 2 2 1 Tau95 Triple barrel domain TFIIF_beta PF02270.15 EMG48358.1 - 0.13 12.5 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain DUF2457 PF10446.9 EMG48358.1 - 2.1 7.4 19.9 2.9 6.9 19.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 EMG48358.1 - 3.2 5.8 15.1 4.5 5.4 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EMG48358.1 - 5.8 4.9 19.9 8.8 4.3 19.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi S-antigen PF05756.11 EMG48358.1 - 7.6 7.0 7.5 7.2 7.1 5.6 2.0 2 0 0 2 2 2 0 S-antigen protein M20_dimer PF07687.14 EMG48359.1 - 7.8e-15 54.7 0.0 1.5e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase dimerisation domain FtsX_ECD PF18075.1 EMG48359.1 - 0.014 16.0 0.3 0.024 15.3 0.3 1.3 1 0 0 1 1 1 0 FtsX extracellular domain YwhD PF08741.10 EMG48359.1 - 0.052 13.2 0.3 0.1 12.3 0.1 1.5 2 0 0 2 2 2 0 YwhD family LRR_8 PF13855.6 EMG48360.1 - 4.9e-12 45.4 24.8 6.4e-07 29.0 0.5 5.7 5 1 1 6 6 6 2 Leucine rich repeat LRR_4 PF12799.7 EMG48360.1 - 1.4e-07 31.7 42.2 0.0047 17.3 0.1 9.5 6 1 4 10 10 10 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMG48360.1 - 0.029 14.4 7.3 4 7.7 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich repeat F-box_4 PF15966.5 EMG48360.1 - 0.034 14.0 0.1 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 F-box F-box PF00646.33 EMG48360.1 - 0.038 13.9 0.4 0.038 13.9 0.4 2.6 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 EMG48360.1 - 0.1 12.5 2.8 0.22 11.5 0.6 2.7 2 1 0 2 2 2 0 F-box-like FNIP PF05725.12 EMG48360.1 - 0.14 12.4 15.6 12 6.2 1.1 6.0 4 2 0 4 4 4 0 FNIP Repeat Pentapeptide_4 PF13599.6 EMG48360.1 - 1.1 9.5 3.5 4.1 7.7 0.3 3.3 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) Carn_acyltransf PF00755.20 EMG48361.1 - 1.7e-188 627.9 0.2 1.9e-188 627.8 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RE_CfrBI PF09516.10 EMG48361.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 CfrBI restriction endonuclease Glyco_transf_21 PF13506.6 EMG48362.1 - 2e-18 66.5 0.0 1.2e-08 34.6 0.1 3.4 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EMG48362.1 - 2.8e-08 34.0 0.0 7.8e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMG48362.1 - 0.0061 16.4 0.0 0.023 14.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 RhoGAP PF00620.27 EMG48363.1 - 3.8e-44 150.2 0.3 1.5e-43 148.3 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EMG48363.1 - 2.3e-13 50.1 26.9 1.9e-08 34.4 8.5 2.4 2 0 0 2 2 2 2 LIM domain HALZ PF02183.18 EMG48363.1 - 0.0061 16.8 1.1 0.0061 16.8 1.1 2.9 3 0 0 3 3 3 1 Homeobox associated leucine zipper Spc7 PF08317.11 EMG48363.1 - 0.074 11.9 9.5 0.051 12.4 2.1 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Complex1_LYR PF05347.15 EMG48364.1 - 3.7e-14 52.5 0.1 4.3e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EMG48364.1 - 0.00016 22.3 0.4 0.00018 22.2 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Clathrin_lg_ch PF01086.17 EMG48365.1 - 3.4e-53 181.1 22.3 4.2e-53 180.8 22.3 1.1 1 0 0 1 1 1 1 Clathrin light chain MFA1_2 PF17317.2 EMG48365.1 - 0.12 12.1 0.0 0.12 12.1 0.0 2.7 3 0 0 3 3 3 0 Mating hormone A-factor 1&2 UPF0542 PF15086.6 EMG48365.1 - 2.2 8.3 5.4 4.1 7.4 5.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 TDA11 PF17084.5 EMG48366.1 - 0.00028 20.0 37.2 0.00075 18.6 37.0 1.9 1 1 0 1 1 1 1 Topoisomerase I damage affected protein 11 Lzipper-MIP1 PF14389.6 EMG48366.1 - 0.22 11.9 8.5 0.73 10.2 0.6 3.2 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CBP4 PF07960.11 EMG48366.1 - 1.9 8.4 5.7 0.41 10.5 1.7 1.9 2 0 0 2 2 2 0 CBP4 F_actin_cap_B PF01115.17 EMG48367.1 - 3.8e-93 311.5 0.7 5.5e-93 311.0 0.7 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pribosyl_synth PF14572.6 EMG48367.1 - 5.1e-31 108.1 0.7 7.9e-31 107.5 0.7 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EMG48367.1 - 5.8e-08 32.4 0.4 3.4e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DNA_PPF PF02916.15 EMG48367.1 - 0.095 13.1 4.3 0.36 11.3 0.3 3.5 4 1 0 5 5 5 0 DNA polymerase processivity factor RFX_DNA_binding PF02257.15 EMG48368.1 - 2.4e-14 53.7 0.0 5.9e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Rubella_E2 PF05749.11 EMG48368.1 - 0.13 11.7 0.2 0.34 10.3 0.2 1.6 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 LRR_8 PF13855.6 EMG48369.1 - 3.2e-19 68.4 24.0 2e-10 40.3 2.8 6.1 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 EMG48369.1 - 6.9e-19 67.6 34.8 4.2e-07 30.2 0.0 8.4 6 2 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EMG48369.1 - 2.9e-06 27.1 17.9 1.1 10.1 0.1 9.7 7 2 1 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 EMG48369.1 - 6.7e-05 22.6 17.3 1.1 9.5 0.0 8.6 10 0 0 10 10 10 2 Leucine Rich repeat FNIP PF05725.12 EMG48369.1 - 0.00052 20.1 29.9 0.027 14.6 0.3 7.4 8 2 0 8 8 8 3 FNIP Repeat F-box PF00646.33 EMG48369.1 - 0.031 14.1 0.0 0.099 12.6 0.0 1.9 1 0 0 1 1 1 0 F-box domain DUF5572 PF17733.1 EMG48370.1 - 1.1e-24 86.0 0.2 2.9e-24 84.6 0.2 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5572) RNase_PH PF01138.21 EMG48371.1 - 3.2e-33 115.1 0.1 4.2e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EMG48371.1 - 2.4e-05 24.3 0.1 6e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mito_carr PF00153.27 EMG48372.1 - 8e-55 182.8 1.6 5.8e-18 64.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein His_Phos_2 PF00328.22 EMG48373.1 - 6.3e-45 154.2 0.0 8.9e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TFIIF_alpha PF05793.12 EMG48374.1 - 6.6e-15 54.7 22.2 3.7e-10 39.0 0.7 3.9 2 1 2 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF383 PF04063.14 EMG48375.1 - 4.5e-68 228.7 3.5 1e-66 224.3 0.9 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EMG48375.1 - 8.9e-24 83.1 1.3 2.4e-23 81.7 1.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Amino_oxidase PF01593.24 EMG48376.1 - 1.4e-53 182.8 0.0 2.2e-53 182.1 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMG48376.1 - 7.3e-11 42.1 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMG48376.1 - 1.7e-06 27.5 0.1 0.00019 20.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMG48376.1 - 5.2e-06 26.1 0.0 7.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMG48376.1 - 2.9e-05 23.5 1.2 0.00086 18.6 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMG48376.1 - 0.00025 19.9 0.2 0.061 12.0 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EMG48376.1 - 0.00097 18.3 0.3 0.0014 17.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMG48376.1 - 0.002 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EMG48376.1 - 0.0033 16.6 0.3 0.012 14.7 0.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EMG48376.1 - 0.011 16.3 0.3 0.047 14.2 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMG48376.1 - 0.021 14.1 0.4 0.031 13.5 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EMG48376.1 - 0.13 11.5 0.2 0.26 10.5 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Kelch_4 PF13418.6 EMG48377.1 - 3.2e-05 23.9 6.6 0.00014 21.8 0.1 4.4 6 0 0 6 6 6 1 Galactose oxidase, central domain Atu4866 PF11512.8 EMG48377.1 - 0.1 13.0 0.3 0.4 11.1 0.1 2.1 2 0 0 2 2 2 0 Agrobacterium tumefaciens protein Atu4866 zf-Tim10_DDP PF02953.15 EMG48378.1 - 5.1e-19 67.7 4.1 6.4e-19 67.4 4.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF825 PF05695.12 EMG48378.1 - 0.052 10.7 0.2 0.051 10.7 0.2 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Cyto_heme_lyase PF01265.17 EMG48379.1 - 1.6e-45 155.9 10.2 3.4e-45 154.9 10.2 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase SURF4 PF02077.15 EMG48380.1 - 1.5e-89 300.2 12.0 1.7e-89 300.0 12.0 1.0 1 0 0 1 1 1 1 SURF4 family MerC PF03203.14 EMG48380.1 - 6.3 7.3 17.2 0.23 11.9 4.9 2.4 2 1 0 2 2 2 0 MerC mercury resistance protein CoA_transf_3 PF02515.17 EMG48381.1 - 4.3e-43 147.8 0.0 1.1e-41 143.2 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Fungal_trans PF04082.18 EMG48382.1 - 7.4e-21 74.4 0.8 2.5e-20 72.6 0.8 2.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG48382.1 - 7.6e-07 29.2 9.5 7.6e-07 29.2 9.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.8 EMG48382.1 - 4.9 7.1 6.7 1.9 8.4 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.11 EMG48382.1 - 5.8 4.9 13.7 0.02 13.0 4.6 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF676 PF05057.14 EMG48383.1 - 8.6e-39 133.3 0.0 1.3e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EMG48383.1 - 4.5e-05 23.4 0.0 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EMG48383.1 - 4.8e-05 23.3 0.0 9.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EMG48383.1 - 0.0041 16.9 0.0 0.0093 15.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.18 EMG48383.1 - 0.061 12.9 0.0 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family ABC1 PF03109.16 EMG48384.1 - 7.4e-23 81.0 0.2 2.2e-15 56.8 0.1 2.6 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.22 EMG48384.1 - 0.0012 18.5 0.7 0.003 17.2 0.1 2.0 2 0 0 2 2 2 1 RIO1 family Fungal_trans PF04082.18 EMG48385.1 - 5.4e-14 51.9 4.6 5.8e-14 51.8 1.8 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG48385.1 - 9.2e-06 25.7 9.9 1.6e-05 24.9 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_2 PF12680.7 EMG48386.1 - 0.12 13.0 0.0 0.15 12.7 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain NUDIX PF00293.28 EMG48387.1 - 3.5e-21 75.6 0.0 1.5e-20 73.6 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain LPD11 PF18824.1 EMG48387.1 - 0.02 14.9 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 LIAS_N PF16881.5 EMG48388.1 - 2.2e-20 73.1 0.2 5e-20 71.9 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EMG48388.1 - 2.5e-14 54.0 0.0 5.1e-14 53.0 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.11 EMG48388.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal AAA_assoc_2 PF16193.5 EMG48388.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA C-terminal domain Hist_deacetyl PF00850.19 EMG48389.1 - 4.2e-52 177.5 0.0 1.8e-50 172.2 0.0 2.3 1 1 0 1 1 1 1 Histone deacetylase domain SF3A3 PF16837.5 EMG48389.1 - 0.16 12.5 6.6 0.55 10.8 6.6 1.9 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 RhoGAP PF00620.27 EMG48390.1 - 4.1e-22 78.7 1.7 2.5e-20 72.9 0.8 3.1 2 1 0 2 2 2 1 RhoGAP domain PH PF00169.29 EMG48390.1 - 6.8e-12 45.8 0.0 2.3e-11 44.1 0.0 2.0 1 0 0 1 1 1 1 PH domain PX PF00787.24 EMG48390.1 - 3.4e-10 39.9 0.3 1.5e-09 37.9 0.3 2.2 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 EMG48390.1 - 0.079 13.4 0.0 0.39 11.1 0.0 2.3 1 0 0 1 1 1 0 Pleckstrin homology domain Glyco_hydro_17 PF00332.18 EMG48392.1 - 3.7e-59 200.9 1.3 4.3e-59 200.7 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Rot1 PF10681.9 EMG48393.1 - 7.3e-44 149.8 0.0 8.3e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Dioxygenase_C PF00775.21 EMG48394.1 - 4.2e-48 163.2 0.0 5.4e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EMG48394.1 - 4.5e-28 96.9 0.1 7.1e-28 96.3 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EMG48394.1 - 8e-07 29.2 0.0 5.1e-06 26.7 0.0 2.2 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EMG48394.1 - 0.008 16.5 0.0 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 EMG48394.1 - 0.12 12.3 0.0 3.5 7.7 0.0 2.6 2 0 0 2 2 2 0 CarboxypepD_reg-like domain Glyco_hydro_38N PF01074.22 EMG48395.1 - 2.2e-77 260.3 0.7 4.4e-77 259.3 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EMG48395.1 - 4.9e-49 167.3 0.3 8.6e-49 166.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EMG48395.1 - 1.5e-21 76.4 0.0 4e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EMG48395.1 - 2.3e-08 34.0 0.0 5.7e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain ARL6IP6 PF15062.6 EMG48396.1 - 0.016 15.3 0.1 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Sod_Cu PF00080.20 EMG48397.1 - 9.4e-31 106.9 0.3 1.1e-30 106.6 0.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SPACA9 PF15120.6 EMG48398.1 - 5.8e-05 22.9 0.2 0.009 15.8 0.1 2.4 2 0 0 2 2 2 2 Sperm acrosome-associated protein 9 LRR_9 PF14580.6 EMG48398.1 - 0.0056 16.2 2.4 0.019 14.5 0.8 2.4 2 1 0 2 2 2 1 Leucine-rich repeat MitMem_reg PF13012.6 EMG48398.1 - 0.0062 17.0 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function LRR_4 PF12799.7 EMG48398.1 - 0.041 14.3 9.6 39 4.8 0.0 5.9 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Methyltrn_RNA_3 PF02598.17 EMG48399.1 - 1e-71 241.8 0.7 1.3e-71 241.5 0.7 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase TBCC_N PF16752.5 EMG48400.1 - 0.031 14.7 3.2 0.031 14.7 3.2 6.6 2 2 4 7 7 7 0 Tubulin-specific chaperone C N-terminal domain Pox_A_type_inc PF04508.12 EMG48400.1 - 0.58 10.1 0.0 0.58 10.1 0.0 4.3 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat ID PF18543.1 EMG48400.1 - 0.59 10.2 4.4 1.5 8.9 0.1 3.5 3 0 0 3 3 3 0 Intracellular delivery domain CT_C_D PF02682.16 EMG48400.1 - 3.2 7.5 9.0 13 5.5 0.5 3.8 2 2 1 3 3 3 0 Carboxyltransferase domain, subdomain C and D Flocculin_t3 PF13928.6 EMG48401.1 - 4.2e-14 52.8 24.7 4.2e-14 52.8 24.7 2.4 3 1 0 3 3 3 1 Flocculin type 3 repeat Flocculin_t3 PF13928.6 EMG48403.1 - 1.9e-22 79.5 45.1 2.6e-12 47.1 16.3 4.7 3 1 1 4 4 4 2 Flocculin type 3 repeat NPP PF08384.10 EMG48403.1 - 0.051 13.6 0.4 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Pro-opiomelanocortin, N-terminal region Prominin PF05478.11 EMG48404.1 - 0.011 13.7 3.4 0.019 13.0 3.4 1.3 1 0 0 1 1 1 0 Prominin DUF4404 PF14357.6 EMG48404.1 - 0.016 15.8 3.3 0.016 15.8 3.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF3671 PF12420.8 EMG48404.1 - 0.048 13.7 0.2 0.048 13.7 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function CALCOCO1 PF07888.11 EMG48404.1 - 0.052 12.4 2.5 0.085 11.7 2.5 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MIEAP PF16026.5 EMG48404.1 - 0.093 12.9 0.8 0.62 10.2 0.1 2.3 2 0 0 2 2 2 0 Mitochondria-eating protein SlyX PF04102.12 EMG48404.1 - 3.4 8.4 9.3 8.5 7.1 7.5 2.5 2 0 0 2 2 2 0 SlyX Thioredoxin PF00085.20 EMG48405.1 - 5.1e-15 55.3 0.1 4.6e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EMG48405.1 - 1.6e-06 28.5 0.5 0.00023 21.6 0.5 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EMG48405.1 - 3.7e-06 26.9 0.1 0.00024 21.0 0.1 2.4 2 1 0 2 2 2 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 EMG48405.1 - 4.4e-06 26.3 1.2 0.00013 21.5 0.8 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EMG48405.1 - 0.0063 16.8 7.7 0.77 10.1 4.7 4.0 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EMG48405.1 - 0.12 12.6 0.1 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like Flocculin_t3 PF13928.6 EMG48406.1 - 1.5e-23 83.0 69.6 4.3e-12 46.3 14.7 8.8 8 2 1 9 9 9 4 Flocculin type 3 repeat CPSF_A PF03178.15 EMG48407.1 - 5.2e-97 325.0 0.1 2.8e-95 319.3 0.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region EPL1 PF10513.9 EMG48407.1 - 0.21 12.0 7.1 1.7 9.0 4.1 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like SDA1 PF05285.12 EMG48407.1 - 1.9 7.8 12.9 1.6 8.1 6.3 2.2 2 0 0 2 2 2 0 SDA1 PIG-F PF06699.11 EMG48408.1 - 2.2e-53 181.1 6.7 2.7e-53 180.8 6.7 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2798 PF11391.8 EMG48408.1 - 0.11 12.5 3.8 8 6.6 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2798) MscS_TM PF12794.7 EMG48408.1 - 0.17 10.8 7.5 0.25 10.2 7.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Redoxin PF08534.10 EMG48409.1 - 1e-36 125.9 0.0 1.1e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EMG48409.1 - 4e-09 36.4 0.0 4.6e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family MqsA_antitoxin PF15731.5 EMG48409.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-Tim10_DDP PF02953.15 EMG48410.1 - 7.1e-21 73.6 0.4 1.2e-20 72.8 0.4 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.8 EMG48410.1 - 0.031 14.7 0.3 0.045 14.2 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) Proteasome PF00227.26 EMG48411.1 - 1.4e-38 132.3 0.1 8.8e-38 129.7 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit zf-C2H2 PF00096.26 EMG48412.1 - 9.8e-07 28.9 18.7 0.00054 20.3 2.3 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMG48412.1 - 3e-05 24.2 9.0 5.4e-05 23.4 4.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-met PF12874.7 EMG48412.1 - 0.0063 16.9 1.7 1.2 9.7 0.0 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EMG48412.1 - 0.01 16.6 17.4 0.085 13.7 0.9 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Spt46 PF17734.1 EMG48412.1 - 0.071 12.9 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 CENP-B_dimeris PF09026.10 EMG48412.1 - 0.4 11.1 5.8 74 3.8 6.2 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EMG48412.1 - 0.72 9.5 3.3 4.1 7.1 0.2 3.3 3 0 0 3 3 3 0 FAM176 family Fungal_trans PF04082.18 EMG48413.1 - 4.2e-15 55.5 0.1 4.2e-15 55.5 0.1 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG48413.1 - 8.5e-08 32.2 10.8 1.7e-07 31.2 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP_sp32 PF07222.12 EMG48413.1 - 0.072 12.5 4.1 0.18 11.2 4.1 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Fungal_trans_2 PF11951.8 EMG48414.1 - 4.6e-28 98.1 1.6 7.2e-28 97.5 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG48414.1 - 5.9e-10 39.1 8.3 5.9e-10 39.1 8.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb4 PF03874.16 EMG48414.1 - 0.97 9.8 0.0 0.97 9.8 0.0 4.2 4 1 1 5 5 5 0 RNA polymerase Rpb4 BTB_2 PF02214.22 EMG48415.1 - 3.3e-07 30.6 3.2 0.00014 22.1 0.4 2.7 3 0 0 3 3 3 2 BTB/POZ domain Dpoe2NT PF12213.8 EMG48415.1 - 0.089 13.1 0.2 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal MFS_1 PF07690.16 EMG48416.1 - 2.5e-30 105.6 47.9 3.3e-28 98.6 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG48416.1 - 0.0027 16.6 21.1 0.0027 16.6 21.1 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Gemini_C4 PF01492.17 EMG48416.1 - 0.026 14.5 0.4 0.043 13.7 0.4 1.3 1 0 0 1 1 1 0 Geminivirus C4 protein LEP503 PF15221.6 EMG48416.1 - 0.13 12.7 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 Sulfate_transp PF00916.20 EMG48418.1 - 4.4e-114 381.2 15.4 5.8e-114 380.8 15.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EMG48418.1 - 0.00024 20.7 0.0 0.00054 19.6 0.0 1.6 1 0 0 1 1 1 1 STAS domain CPBP PF02517.16 EMG48418.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.9 3 2 0 3 3 3 0 CPBP intramembrane metalloprotease FGGY_C PF02782.16 EMG48419.1 - 4.7e-55 186.4 0.1 7e-55 185.8 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EMG48419.1 - 3.1e-21 76.1 0.0 2.4e-20 73.1 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 EMG48419.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Hexokinase CBFD_NFYB_HMF PF00808.23 EMG48420.1 - 4.4e-13 49.3 1.1 8.8e-13 48.3 1.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMG48420.1 - 0.00016 22.0 1.5 0.00032 21.0 1.5 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SAP130_C PF16014.5 EMG48420.1 - 0.037 13.1 0.3 0.044 12.9 0.3 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus RNA_pol_Rpo13 PF12136.8 EMG48420.1 - 0.098 12.6 2.4 0.81 9.6 0.8 2.7 3 0 0 3 3 3 0 RNA polymerase Rpo13 subunit HTH domain tRNA_int_endo PF01974.17 EMG48421.1 - 2.6e-28 97.9 0.4 5.1e-28 97.0 0.4 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EMG48421.1 - 0.025 14.2 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain adh_short PF00106.25 EMG48422.1 - 5.3e-17 61.9 0.1 1e-14 54.5 0.1 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMG48422.1 - 6.1e-09 35.8 0.0 2.8e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG48422.1 - 1.5e-08 34.8 0.0 2.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMG48422.1 - 5.2e-07 29.4 0.0 7.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMG48422.1 - 0.0099 15.0 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EMG48422.1 - 0.013 14.7 0.1 0.021 14.0 0.1 1.4 1 1 0 1 1 1 0 Male sterility protein GDP_Man_Dehyd PF16363.5 EMG48422.1 - 0.056 12.8 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase APG6 PF04111.12 EMG48423.1 - 6.3e-53 179.4 0.9 6.3e-53 179.4 0.9 2.3 2 0 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 EMG48423.1 - 5.2e-24 85.3 23.1 5.2e-24 85.3 23.1 2.1 2 0 0 2 2 2 1 Apg6 coiled-coil region Zn_clus PF00172.18 EMG48424.1 - 5.6e-07 29.6 6.9 5.6e-07 29.6 6.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EMP70 PF02990.16 EMG48425.1 - 7.7e-196 651.8 17.4 1.2e-195 651.2 17.4 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.6 EMG48425.1 - 1.8 8.2 5.3 5.9 6.5 2.7 2.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Zn_clus PF00172.18 EMG48426.1 - 3.6e-07 30.2 11.9 5.5e-07 29.6 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RSN1_7TM PF02714.15 EMG48427.1 - 8.4e-61 205.7 19.7 8.4e-61 205.7 19.7 1.4 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EMG48427.1 - 9.8e-14 52.0 0.0 1.4e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EMG48427.1 - 4.1e-08 33.1 3.4 4.9e-08 32.9 0.2 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Rad4 PF03835.15 EMG48429.1 - 1.5e-22 79.9 0.4 5.3e-22 78.1 0.0 2.2 2 1 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EMG48429.1 - 1e-19 70.7 0.1 2.2e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 EMG48429.1 - 2.3e-13 50.9 0.0 2.3e-13 50.9 0.0 3.3 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 EMG48429.1 - 4.1e-13 49.0 0.5 1.1e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 EMG48429.1 - 0.16 12.4 0.0 0.59 10.6 0.0 1.9 1 1 0 1 1 1 0 Transglutaminase-like superfamily RNase_H2_suC PF08615.11 EMG48430.1 - 3.7e-16 59.6 0.0 1.7e-15 57.5 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MFS_1 PF07690.16 EMG48431.1 - 6.3e-44 150.3 55.8 1.5e-43 149.1 54.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG48431.1 - 2.3e-11 43.2 15.7 2.3e-11 43.2 15.7 2.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMG48431.1 - 2.9e-10 39.2 15.2 5.3e-08 31.7 12.3 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EMG48431.1 - 6.8e-05 21.9 7.9 6.8e-05 21.9 7.9 3.2 3 2 0 3 3 3 1 MFS_1 like family EamA PF00892.20 EMG48432.1 - 3.9e-13 49.8 25.7 9.9e-11 42.0 0.2 3.0 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 EMG48432.1 - 5.1e-09 35.8 4.0 5.1e-09 35.8 4.0 2.5 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 EMG48432.1 - 8.1e-06 25.3 14.4 8.1e-06 25.3 14.4 1.4 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.16 EMG48432.1 - 1.8e-05 24.3 14.1 4.9e-05 22.8 13.6 2.0 1 1 1 2 2 2 2 Triose-phosphate Transporter family DUF5411 PF17424.2 EMG48432.1 - 0.098 12.6 2.1 0.16 11.9 0.3 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5411) NDUF_B4 PF07225.12 EMG48432.1 - 0.13 12.1 0.9 3.7 7.5 0.0 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) HlyIII PF03006.20 EMG48432.1 - 3.9 7.1 17.3 0.19 11.4 9.5 2.2 1 1 2 3 3 3 0 Haemolysin-III related H_PPase PF03030.16 EMG48432.1 - 7.1 5.1 12.5 1.1e+02 1.2 11.7 2.3 1 1 0 1 1 1 0 Inorganic H+ pyrophosphatase DIOX_N PF14226.6 EMG48433.1 - 7.3e-18 65.4 0.0 1.3e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMG48433.1 - 1.1e-14 54.7 0.0 2.4e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Kelch_6 PF13964.6 EMG48433.1 - 0.051 13.9 0.1 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Kelch motif Met_10 PF02475.16 EMG48434.1 - 2.1e-70 236.5 0.0 3.2e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 EMG48434.1 - 0.0067 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MethyltransfD12 PF02086.15 EMG48434.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase DUF3201 PF11447.8 EMG48434.1 - 0.04 13.4 0.7 4.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) PrmA PF06325.13 EMG48434.1 - 0.21 11.0 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ECR1_N PF14382.6 EMG48435.1 - 8.9e-15 54.2 0.0 1.8e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EMG48435.1 - 3.1e-07 30.6 0.0 8.3e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EMG48435.1 - 0.0089 16.6 0.0 0.53 10.9 0.0 2.4 1 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 PCRF PF03462.18 EMG48436.1 - 9.4e-48 162.7 2.8 9.4e-48 162.6 0.0 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EMG48436.1 - 2.8e-34 117.5 4.5 5.4e-34 116.6 4.5 1.5 1 0 0 1 1 1 1 RF-1 domain Oxysterol_BP PF01237.18 EMG48438.1 - 2.5e-104 349.1 2.7 2.8e-104 348.9 1.2 1.8 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 EMG48438.1 - 1.1e-37 128.2 0.4 2.3e-37 127.1 0.4 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EMG48438.1 - 5.1e-07 30.2 0.3 2.5e-06 27.9 0.2 2.3 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 EMG48438.1 - 0.00017 21.6 0.1 0.00042 20.4 0.1 1.6 1 0 0 1 1 1 1 PH domain zf-RING_UBOX PF13445.6 EMG48439.1 - 2.8e-09 36.8 6.0 2.8e-09 36.8 6.0 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EMG48439.1 - 5.6e-06 26.1 7.3 5.6e-06 26.1 7.3 3.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMG48439.1 - 1.5e-05 24.7 7.0 1.5e-05 24.7 7.0 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMG48439.1 - 2.5e-05 24.5 4.6 2.5e-05 24.5 4.6 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 EMG48439.1 - 0.00011 22.3 5.8 0.00011 22.3 5.8 2.4 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EMG48439.1 - 0.00036 20.4 5.5 0.00036 20.4 5.5 3.1 2 1 0 2 2 1 1 zinc-RING finger domain zf-Nse PF11789.8 EMG48439.1 - 0.0011 18.7 2.1 0.0011 18.7 2.1 2.4 2 1 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 EMG48439.1 - 0.002 18.0 6.3 0.002 18.0 6.3 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Csm1_N PF18504.1 EMG48439.1 - 0.042 14.2 1.5 0.16 12.4 0.3 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain Cript PF10235.9 EMG48439.1 - 1.3 9.7 15.3 0.43 11.2 7.0 2.7 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT zf-RING_6 PF14835.6 EMG48439.1 - 1.4 8.8 6.8 0.28 11.1 2.4 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein G_glu_transpept PF01019.21 EMG48440.1 - 2.1e-121 406.2 0.0 2.4e-121 406.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ABC2_membrane PF01061.24 EMG48441.1 - 4.8e-78 261.4 53.2 6e-41 140.2 25.0 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EMG48441.1 - 1e-41 142.7 0.0 1.2e-19 71.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EMG48441.1 - 2.9e-29 100.8 1.8 5.6e-25 87.1 0.2 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EMG48441.1 - 4.9e-17 62.3 0.0 1.6e-16 60.6 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EMG48441.1 - 1.7e-07 31.3 0.0 2.9e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EMG48441.1 - 5e-07 29.5 0.5 0.00017 21.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EMG48441.1 - 2.1e-05 23.8 38.3 0.00056 19.1 11.8 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 EMG48441.1 - 4.4e-05 23.1 0.3 0.0066 16.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EMG48441.1 - 0.00011 22.7 0.4 0.00042 20.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EMG48441.1 - 0.00021 21.4 0.2 0.06 13.4 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 EMG48441.1 - 0.00036 20.1 0.1 0.072 12.5 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMG48441.1 - 0.00052 19.9 0.0 0.38 10.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EMG48441.1 - 0.0011 18.8 0.1 0.24 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMG48441.1 - 0.0012 19.4 0.1 0.017 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EMG48441.1 - 0.0025 18.4 0.2 0.043 14.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 EMG48441.1 - 0.0034 17.7 1.4 0.0051 17.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMG48441.1 - 0.0094 16.1 0.1 0.12 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EMG48441.1 - 0.012 16.1 0.3 0.73 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EMG48441.1 - 0.013 15.8 0.9 0.14 12.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 EMG48441.1 - 0.022 14.4 2.4 0.48 10.0 0.6 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EMG48441.1 - 0.045 13.7 2.5 0.43 10.5 0.1 2.7 3 0 0 3 3 2 0 NACHT domain TsaE PF02367.17 EMG48441.1 - 0.048 13.7 0.1 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EMG48441.1 - 0.059 13.1 0.1 0.92 9.2 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein Thymidylate_kin PF02223.17 EMG48441.1 - 0.12 12.0 0.2 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase dNK PF01712.19 EMG48441.1 - 0.13 12.1 0.2 2.7 7.8 0.0 2.7 3 0 0 3 3 2 0 Deoxynucleoside kinase FtsK_SpoIIIE PF01580.18 EMG48441.1 - 0.15 11.4 0.0 7.7 5.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 EMG48441.1 - 0.4 10.6 3.6 3.3 7.6 0.5 3.0 3 0 0 3 3 3 0 NTPase Herpes_capsid PF06112.11 EMG48442.1 - 0.35 10.9 20.1 0.14 12.2 15.9 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Period_C PF12114.8 EMG48442.1 - 2.1 7.9 10.6 3 7.4 10.6 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region ELP6 PF09807.9 EMG48444.1 - 1.2e-05 24.9 0.0 0.00085 18.8 0.0 2.2 1 1 1 2 2 2 2 Elongation complex protein 6 DrrA_P4M PF14860.6 EMG48444.1 - 0.0097 15.7 0.8 0.02 14.7 0.8 1.5 1 0 0 1 1 1 1 DrrA phosphatidylinositol 4-phosphate binding domain DUF3336 PF11815.8 EMG48445.1 - 1.4e-34 118.8 4.2 2.7e-34 117.9 4.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EMG48445.1 - 7.2e-06 26.3 0.3 2.4e-05 24.6 0.2 1.9 1 1 0 2 2 2 1 Patatin-like phospholipase PP2C_2 PF13672.6 EMG48446.1 - 8.3e-11 41.9 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EMG48446.1 - 8.9e-09 35.5 0.0 1.7e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EMG48446.1 - 7.2e-05 22.5 0.2 0.057 13.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C nos_propeller PF18764.1 EMG48446.1 - 0.035 14.0 0.4 0.088 12.7 0.1 1.8 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat DUF4108 PF13390.6 EMG48446.1 - 0.036 14.0 0.2 0.065 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) DUF3954 PF13128.6 EMG48446.1 - 0.15 11.9 0.0 14 5.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3954) AAA_5 PF07728.14 EMG48447.1 - 2.5e-130 429.2 0.8 1.8e-26 92.8 0.0 8.7 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EMG48447.1 - 3.9e-50 168.5 0.2 1.1e-18 67.4 0.0 5.0 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_3 PF07726.11 EMG48447.1 - 1.3e-33 115.7 0.0 1.4e-08 34.7 0.0 7.2 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EMG48447.1 - 8.1e-31 106.9 5.4 3.9e-06 26.5 0.0 7.5 7 0 0 7 7 7 5 P-loop containing dynein motor region AAA PF00004.29 EMG48447.1 - 9.6e-31 106.9 0.1 0.00014 22.3 0.0 7.2 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 EMG48447.1 - 2.8e-29 101.3 0.0 7e-26 90.4 0.0 4.5 3 0 0 3 3 3 1 Midasin AAA lid domain Dynein_heavy PF03028.15 EMG48447.1 - 1.1e-24 86.9 0.3 1.5e-05 25.0 0.0 9.0 9 0 0 9 9 8 5 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 EMG48447.1 - 1.2e-20 73.9 0.2 0.00048 19.9 0.0 6.3 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_6 PF12774.7 EMG48447.1 - 1.2e-19 70.5 4.2 0.052 12.5 0.3 10.5 10 2 0 10 10 10 4 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 EMG48447.1 - 1.7e-19 70.5 2.4 0.00048 20.4 0.0 8.1 7 1 0 7 7 6 4 AAA domain AAA_16 PF13191.6 EMG48447.1 - 2.6e-19 70.2 16.4 0.0042 17.5 0.8 8.7 8 2 0 8 8 6 5 AAA ATPase domain AAA_14 PF13173.6 EMG48447.1 - 3e-18 66.1 0.9 0.017 15.1 0.0 8.6 7 1 1 8 8 7 3 AAA domain TsaE PF02367.17 EMG48447.1 - 1.4e-17 63.9 3.1 0.082 12.9 0.1 7.0 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EMG48447.1 - 3.6e-17 62.7 2.8 0.027 14.2 0.0 7.0 8 0 0 8 8 6 5 AAA domain Sigma54_activ_2 PF14532.6 EMG48447.1 - 1.2e-14 54.6 0.4 0.066 13.3 0.0 6.9 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_18 PF13238.6 EMG48447.1 - 7e-14 52.5 13.5 0.064 13.8 0.1 8.7 8 0 0 8 8 6 4 AAA domain RNA_helicase PF00910.22 EMG48447.1 - 1.6e-13 51.0 5.7 0.62 10.5 0.0 8.5 8 0 0 8 8 7 2 RNA helicase T2SSE PF00437.20 EMG48447.1 - 3.7e-13 49.2 8.0 0.023 13.8 0.0 6.6 7 0 0 7 7 6 4 Type II/IV secretion system protein ABC_tran PF00005.27 EMG48447.1 - 4.4e-13 49.9 15.8 0.00096 19.7 0.0 7.5 7 0 0 7 7 6 3 ABC transporter AAA_33 PF13671.6 EMG48447.1 - 2.8e-12 47.0 0.3 0.021 15.0 0.0 6.2 6 0 0 6 6 6 3 AAA domain Rad17 PF03215.15 EMG48447.1 - 5.2e-11 42.8 2.6 0.055 13.4 0.1 6.4 6 0 0 6 6 5 2 Rad17 P-loop domain Mg_chelatase PF01078.21 EMG48447.1 - 1.6e-10 40.7 0.2 0.39 10.1 0.0 7.7 8 0 0 8 8 8 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EMG48447.1 - 4.3e-10 39.2 4.7 0.36 10.1 0.0 6.6 7 0 0 7 7 6 2 Zeta toxin NACHT PF05729.12 EMG48447.1 - 4.6e-10 39.7 5.3 0.45 10.4 0.0 6.2 6 0 0 6 6 5 3 NACHT domain RuvB_N PF05496.12 EMG48447.1 - 6.3e-10 39.0 4.7 0.045 13.5 0.0 6.7 7 0 0 7 7 7 3 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EMG48447.1 - 2.8e-09 37.1 7.1 0.45 10.4 0.5 6.5 7 0 0 7 7 5 2 RsgA GTPase IstB_IS21 PF01695.17 EMG48447.1 - 7.4e-08 32.3 0.5 0.082 12.6 0.0 6.3 7 0 0 7 7 6 1 IstB-like ATP binding protein PduV-EutP PF10662.9 EMG48447.1 - 1.5e-07 31.2 4.0 0.31 10.8 0.1 5.9 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EMG48447.1 - 2.8e-07 30.2 0.1 2.8 7.8 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain VWA PF00092.28 EMG48447.1 - 3.3e-07 30.7 1.0 2e-06 28.2 1.0 2.5 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_28 PF13521.6 EMG48447.1 - 3.7e-07 30.5 7.0 1.6 9.0 0.1 7.4 7 0 0 7 7 7 1 AAA domain DUF815 PF05673.13 EMG48447.1 - 5.7e-07 28.9 3.0 0.14 11.3 0.1 5.3 6 0 0 6 6 6 2 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 EMG48447.1 - 1.3e-06 28.4 1.2 0.8 9.5 0.1 5.7 6 0 0 6 6 6 1 Bacterial dnaA protein AAA_25 PF13481.6 EMG48447.1 - 2.4e-06 27.3 2.8 4 7.0 0.0 5.1 5 0 0 5 5 4 0 AAA domain Viral_helicase1 PF01443.18 EMG48447.1 - 3.9e-06 26.8 0.3 0.8 9.4 0.0 5.2 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase Roc PF08477.13 EMG48447.1 - 4.9e-06 26.8 4.0 5.2 7.3 0.1 6.7 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 EMG48447.1 - 6.9e-06 26.5 10.2 0.85 9.9 0.4 6.0 6 0 0 6 6 5 1 AAA domain TniB PF05621.11 EMG48447.1 - 8.7e-06 25.3 2.4 1.3 8.4 0.0 5.7 7 0 0 7 7 5 1 Bacterial TniB protein MMR_HSR1 PF01926.23 EMG48447.1 - 1.2e-05 25.4 6.5 3.8 7.6 0.0 6.8 6 0 0 6 6 6 0 50S ribosome-binding GTPase SRP54 PF00448.22 EMG48447.1 - 1.8e-05 24.5 8.6 0.42 10.2 0.3 5.6 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 EMG48447.1 - 0.00012 22.0 11.7 1.7 8.6 0.6 6.2 6 0 0 6 6 5 1 NTPase ATP-synt_ab PF00006.25 EMG48447.1 - 0.00018 21.2 0.0 8.2 6.0 0.0 3.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_8 PF12780.7 EMG48447.1 - 0.0027 17.1 0.0 8.7 5.6 0.0 4.8 4 0 0 4 4 4 0 P-loop containing dynein motor region D4 PhoH PF02562.16 EMG48447.1 - 0.0029 17.1 5.2 2.9 7.3 0.2 4.6 4 0 0 4 4 4 1 PhoH-like protein ResIII PF04851.15 EMG48447.1 - 0.0058 16.7 11.9 4.2 7.4 0.0 6.0 6 0 0 6 6 4 0 Type III restriction enzyme, res subunit CbiA PF01656.23 EMG48447.1 - 0.0073 16.4 4.2 27 4.8 0.0 5.3 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 EMG48447.1 - 0.0087 15.4 4.3 8.5 5.6 0.1 5.4 5 0 0 5 5 5 0 KaiC PRK PF00485.18 EMG48447.1 - 0.0092 15.7 1.7 2.1 8.0 0.0 4.3 5 0 0 5 5 3 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 EMG48447.1 - 0.0099 15.7 1.6 13 5.6 0.0 5.1 6 1 0 6 6 3 0 Chloramphenicol phosphotransferase-like protein VWA_2 PF13519.6 EMG48447.1 - 0.034 14.8 1.5 0.13 13.0 0.1 2.9 2 0 0 2 2 1 0 von Willebrand factor type A domain ATP_bind_1 PF03029.17 EMG48447.1 - 0.23 11.2 14.4 6.6 6.4 0.4 6.5 7 0 0 7 7 6 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.17 EMG48447.1 - 0.26 10.9 4.4 3.7 7.2 0.0 3.8 4 0 0 4 4 2 0 Thymidylate kinase Mur_ligase_M PF08245.12 EMG48447.1 - 0.61 10.0 3.5 6.2 6.8 0.0 3.2 2 0 0 2 2 2 0 Mur ligase middle domain IPT PF01745.16 EMG48447.1 - 3.5 7.0 6.3 73 2.6 0.0 4.8 6 0 0 6 6 6 0 Isopentenyl transferase Retrotrans_gag PF03732.17 EMG48449.1 - 0.0014 18.8 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein PolyA_pol_RNAbd PF12627.7 EMG48451.1 - 4.1e-11 42.5 0.2 1.2e-10 41.0 0.1 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A PolyA_pol PF01743.20 EMG48451.1 - 4.5e-11 43.3 0.1 1.5e-10 41.6 0.1 1.9 1 0 0 1 1 1 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.6 EMG48451.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative EPSP_synthase PF00275.20 EMG48452.1 - 6.4e-134 446.8 0.0 9e-134 446.3 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EMG48452.1 - 5e-101 337.3 0.0 7.9e-101 336.6 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EMG48452.1 - 1.5e-48 166.0 0.0 3.4e-48 164.9 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EMG48452.1 - 1.6e-33 116.1 0.2 6.8e-33 114.0 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EMG48452.1 - 2.2e-22 79.1 0.0 6.5e-22 77.6 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 EMG48452.1 - 1.5e-08 34.6 0.0 3.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 EMG48452.1 - 7.3e-08 32.0 0.0 1.9e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EMG48452.1 - 1.4e-07 31.6 0.0 4.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_18 PF13238.6 EMG48452.1 - 0.00065 20.3 0.0 0.0017 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Fe-ADH PF00465.19 EMG48452.1 - 0.0037 16.1 0.2 0.01 14.7 0.2 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.6 EMG48452.1 - 0.0039 17.3 0.0 0.0096 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sacchrp_dh_NADP PF03435.18 EMG48452.1 - 0.013 15.8 0.0 0.089 13.0 0.0 2.5 3 0 0 3 3 2 0 Saccharopine dehydrogenase NADP binding domain YqgF PF14639.6 EMG48452.1 - 0.013 15.3 0.1 0.037 13.8 0.1 1.7 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 AAA_22 PF13401.6 EMG48452.1 - 0.03 14.6 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMG48452.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EMG48452.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMG48452.1 - 0.16 12.3 0.0 0.53 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_M22 PF00814.25 EMG48454.1 - 8.2e-52 176.6 0.0 1.2e-51 176.0 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family YycC PF14174.6 EMG48454.1 - 0.066 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 YycC-like protein Nse4_C PF08743.10 EMG48455.1 - 3.9e-26 91.1 1.4 7.1e-26 90.3 0.0 2.2 3 0 0 3 3 3 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EMG48455.1 - 1.6e-06 28.1 3.6 4.9e-06 26.6 3.6 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Mlh1_C PF16413.5 EMG48456.1 - 1.1e-71 241.3 5.5 7.3e-71 238.7 5.5 2.3 1 1 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EMG48456.1 - 2.7e-34 117.4 0.1 6.9e-34 116.1 0.1 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EMG48456.1 - 1.6e-11 44.2 0.0 3.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EMG48456.1 - 3.8e-05 24.2 0.0 8.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF648 PF04890.13 EMG48456.1 - 0.055 13.2 2.1 0.089 12.5 2.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF648) CDC27 PF09507.10 EMG48456.1 - 0.52 9.6 11.1 0.77 9.1 11.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TPR_14 PF13428.6 EMG48457.1 - 0.0043 17.8 0.0 3.2 8.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EMG48457.1 - 0.04 13.1 0.9 0.2 10.8 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Tom37_C PF11801.8 EMG48457.1 - 0.052 13.5 3.7 0.17 11.9 3.7 1.8 1 0 0 1 1 1 0 Tom37 C-terminal domain TPR_17 PF13431.6 EMG48457.1 - 0.076 13.4 5.8 6.3 7.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMG48457.1 - 0.89 9.3 3.1 41 4.0 0.2 3.5 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.28 EMG48457.1 - 2.2 8.2 10.6 0.51 10.2 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.18 EMG48458.1 - 3.2e-08 33.6 5.1 5.6e-08 32.8 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP1_N PF06424.12 EMG48458.1 - 4.8 7.6 13.5 0.18 12.2 4.2 2.8 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal SUI1 PF01253.22 EMG48459.1 - 2.2e-21 76.1 2.7 4.6e-21 75.1 2.7 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cgr1 PF03879.14 EMG48459.1 - 0.0072 16.7 6.7 0.0072 16.7 6.7 1.9 2 0 0 2 2 2 1 Cgr1 family adh_short_C2 PF13561.6 EMG48461.1 - 6.2e-47 160.1 0.5 7.2e-47 159.9 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMG48461.1 - 1.3e-36 125.9 1.0 1.6e-36 125.6 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG48461.1 - 5.1e-12 46.1 0.6 7.1e-12 45.6 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMG48461.1 - 0.027 13.9 0.3 0.036 13.5 0.3 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mito_carr PF00153.27 EMG48462.1 - 1.9e-61 204.0 2.8 3e-21 75.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMG48462.1 - 0.01 15.0 0.6 0.35 10.0 0.1 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Ribosomal_L24e PF01246.20 EMG48463.1 - 2.9e-30 104.3 3.0 2.9e-30 104.3 3.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L24e TRAP_alpha PF03896.16 EMG48463.1 - 5.3 6.2 9.6 7.6 5.6 9.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HECT PF00632.25 EMG48464.1 - 7e-89 298.3 1.8 7e-89 298.3 1.8 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EMG48464.1 - 0.031 14.0 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Hydrolase_6 PF13344.6 EMG48465.1 - 2.1e-26 92.0 0.0 3.8e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMG48465.1 - 1.7e-11 44.0 0.0 3.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EMG48465.1 - 1.7e-09 38.3 0.0 3.7e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMG48465.1 - 2.7e-08 34.1 0.8 0.0036 17.4 0.1 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 EMG48466.1 - 8.9e-07 29.4 0.0 4.2e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EMG48466.1 - 1.6e-05 25.0 0.4 1.6e-05 25.0 0.4 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EMG48466.1 - 0.013 15.7 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMG48466.1 - 0.017 15.1 0.5 0.73 9.8 0.2 3.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EMG48466.1 - 0.027 14.9 0.1 0.074 13.5 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Goodbye PF17109.5 EMG48466.1 - 0.039 14.4 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Suppressor_APC PF11414.8 EMG48466.1 - 0.2 11.7 3.3 0.96 9.6 0.1 3.0 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein MFS_1 PF07690.16 EMG48467.1 - 4.3e-11 42.3 38.8 7.1e-11 41.6 36.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMG48467.1 - 1.9e-06 26.6 22.9 2.5e-06 26.2 22.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0542 PF15086.6 EMG48467.1 - 0.16 11.9 1.6 0.76 9.7 0.3 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 Rpp20 PF12328.8 EMG48468.1 - 9.6e-30 103.3 2.2 1.6e-29 102.7 2.2 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EMG48468.1 - 5e-06 26.2 1.6 8e-06 25.6 1.6 1.3 1 0 0 1 1 1 1 Alba Metallophos PF00149.28 EMG48470.1 - 1.1e-05 26.1 6.1 1.1e-05 26.1 6.1 2.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Fungus-induced PF10917.8 EMG48470.1 - 0.046 14.0 0.3 0.084 13.2 0.3 1.4 1 0 0 1 1 1 0 Fungus-induced protein HlyC PF02794.16 EMG48470.1 - 0.091 12.7 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 RTX toxin acyltransferase family Pam16 PF03656.13 EMG48471.1 - 3.2e-07 30.4 0.1 3.9e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EMG48471.1 - 0.00035 20.6 0.1 0.00058 19.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Histone PF00125.24 EMG48472.1 - 9.4e-42 142.5 0.6 1e-41 142.4 0.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EMG48472.1 - 2e-06 28.1 0.0 2.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EMG48472.1 - 2.6e-05 24.3 0.1 3.2e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EMG48472.1 - 0.0045 17.2 0.1 0.0064 16.8 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EMG48472.1 - 0.091 12.8 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Y_phosphatase2 PF03162.13 EMG48473.1 - 7.7e-57 191.5 0.2 1.3e-56 190.8 0.2 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EMG48473.1 - 3e-07 30.7 0.0 4.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EMG48473.1 - 0.00018 21.3 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMG48473.1 - 0.003 17.2 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Aminotran_1_2 PF00155.21 EMG48474.1 - 6.2e-77 259.2 0.0 7e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DNA_gyraseB PF00204.25 EMG48474.1 - 0.076 12.5 0.4 4 6.9 0.2 2.4 2 1 0 2 2 2 0 DNA gyrase B Glyco_transf_15 PF01793.16 EMG48475.1 - 2.2e-89 300.0 20.1 6.3e-58 196.6 2.2 2.9 3 0 0 3 3 3 2 Glycolipid 2-alpha-mannosyltransferase Sds3 PF08598.11 EMG48475.1 - 2e-58 198.0 8.8 2e-58 198.0 8.8 2.1 2 1 0 2 2 2 1 Sds3-like DUF3069 PF11269.8 EMG48475.1 - 4.4 7.6 6.2 6.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) Acetyltransf_1 PF00583.25 EMG48476.1 - 7.5e-06 26.2 0.1 1.7e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EMG48476.1 - 0.01 16.5 0.0 0.034 14.8 0.0 1.7 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMG48476.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_12 PF13087.6 EMG48478.1 - 1.2e-57 194.8 0.0 2.9e-57 193.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMG48478.1 - 2.7e-35 122.4 17.6 2.7e-18 66.7 0.0 3.6 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.6 EMG48478.1 - 4.7e-13 49.7 0.1 2.4e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMG48478.1 - 8.7e-12 45.2 0.0 3.5e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EMG48478.1 - 4.1e-05 23.4 0.0 0.038 13.7 0.0 3.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UPF1_Zn_bind PF09416.10 EMG48478.1 - 0.00041 20.4 1.2 0.0012 18.9 1.2 1.8 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) ResIII PF04851.15 EMG48478.1 - 0.00081 19.4 0.0 0.00081 19.4 0.0 2.9 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EMG48478.1 - 0.0011 18.5 0.1 0.031 13.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein zf-C2H2_jaz PF12171.8 EMG48478.1 - 0.0014 18.9 0.5 0.0058 16.9 0.5 2.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DEAD PF00270.29 EMG48478.1 - 0.0019 18.0 0.5 0.47 10.2 0.1 2.4 1 1 0 2 2 2 1 DEAD/DEAH box helicase ATPase_2 PF01637.18 EMG48478.1 - 0.0022 17.9 0.9 0.0036 17.3 0.0 1.7 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 EMG48478.1 - 0.0055 17.1 0.0 0.02 15.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-C2H2_2 PF12756.7 EMG48478.1 - 0.0059 16.9 2.6 0.0084 16.4 1.3 2.0 2 0 0 2 2 1 1 C2H2 type zinc-finger (2 copies) AAA_22 PF13401.6 EMG48478.1 - 0.046 14.0 0.0 0.22 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMG48478.1 - 0.068 13.6 0.0 0.49 10.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 EMG48478.1 - 0.075 12.3 0.1 2 7.6 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 EMG48478.1 - 0.12 12.4 0.0 1 9.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain zf-RING_14 PF17978.1 EMG48478.1 - 0.13 12.7 2.2 0.53 10.7 0.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain AAA_16 PF13191.6 EMG48478.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF4428 PF14471.6 EMG48478.1 - 1.9 8.5 6.0 0.67 9.9 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-CHY PF05495.12 EMG48478.1 - 6.6 7.3 6.7 3.5 8.2 2.2 2.4 1 1 1 2 2 2 0 CHY zinc finger ATG7_N PF16420.5 EMG48479.1 - 9.8e-55 186.3 4.8 5.9e-54 183.7 4.8 2.0 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EMG48479.1 - 2.6e-43 148.2 0.0 4.1e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 EMG48479.1 - 0.0014 18.0 0.0 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMG48479.1 - 0.0017 18.4 0.0 0.0093 16.0 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GCP_N_terminal PF17681.1 EMG48480.1 - 1.3e-45 156.4 3.0 2.5e-45 155.5 3.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EMG48480.1 - 3.6e-21 75.9 4.2 3.6e-21 75.9 4.2 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal RIG-I_C PF18119.1 EMG48480.1 - 0.0013 18.7 2.7 0.0021 18.1 0.0 2.7 3 0 0 3 3 3 1 RIG-I receptor C-terminal domain Proteasome PF00227.26 EMG48481.1 - 5.8e-55 185.7 0.1 7.6e-55 185.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMG48481.1 - 2.5e-12 46.2 0.0 5.2e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ATP-grasp_2 PF08442.10 EMG48482.1 - 1.3e-70 237.1 0.0 2.2e-70 236.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EMG48482.1 - 4e-24 85.2 0.8 8.7e-24 84.1 0.1 2.0 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 EMG48482.1 - 5.1e-11 42.5 0.2 1.2e-10 41.2 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EMG48482.1 - 9.3e-05 22.3 0.1 0.0012 18.6 0.1 2.2 1 1 1 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CIAPIN1 PF05093.13 EMG48483.1 - 5.6e-40 135.9 3.0 5.6e-40 135.9 3.0 2.2 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EMG48483.1 - 5.4e-35 120.5 0.6 1.1e-34 119.5 0.2 1.7 2 0 0 2 2 2 1 Fe-S cluster assembly protein DRE2 N-terminus MFS_1 PF07690.16 EMG48484.1 - 1.3e-20 73.6 20.8 3.9e-20 72.1 18.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily NAD_binding_6 PF08030.12 EMG48486.1 - 2.5e-22 79.7 0.3 5.6e-22 78.5 0.1 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMG48486.1 - 9.4e-22 77.2 0.0 2e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EMG48486.1 - 3.9e-21 75.5 16.7 3.9e-21 75.5 16.7 2.4 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EMG48486.1 - 0.05 14.3 0.1 0.18 12.5 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Phage_holin_2_1 PF04971.12 EMG48486.1 - 0.15 12.1 1.8 17 5.5 0.1 2.7 2 0 0 2 2 2 0 Bacteriophage P21 holin S NMD3 PF04981.13 EMG48487.1 - 3.2e-84 282.2 1.9 3.2e-84 282.2 1.9 1.5 2 0 0 2 2 2 1 NMD3 family VPS11_C PF12451.8 EMG48487.1 - 0.051 13.8 3.5 0.1 12.8 3.5 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal FYVE PF01363.21 EMG48487.1 - 0.13 12.4 1.0 1.1 9.5 0.2 2.5 2 0 0 2 2 2 0 FYVE zinc finger HypA PF01155.19 EMG48487.1 - 0.81 9.7 5.9 3.4 7.7 0.1 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EMG48487.1 - 1.8 8.7 6.8 52 4.0 6.8 2.6 1 1 0 1 1 1 0 Double zinc ribbon Bromodomain PF00439.25 EMG48488.1 - 7.7e-26 90.0 1.7 1.6e-25 89.0 1.7 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EMG48488.1 - 1.3e-08 35.1 1.1 1.6e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMG48488.1 - 3.2e-06 27.1 0.0 7.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMG48488.1 - 0.00093 19.6 0.1 0.0018 18.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CDC45 PF02724.14 EMG48488.1 - 0.36 9.1 20.7 0.47 8.7 20.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 EMG48488.1 - 0.46 10.8 16.0 1.3 9.4 16.0 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 EMG48488.1 - 1.1 7.3 32.1 1.6 6.9 32.1 1.1 1 0 0 1 1 1 0 Nop14-like family Glucosamine_iso PF01182.20 EMG48489.1 - 2.6e-65 220.5 0.0 2.9e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CPDase PF07823.11 EMG48490.1 - 2.4e-49 167.8 4.1 2.5e-48 164.4 4.1 2.0 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EMG48490.1 - 7.7e-07 29.1 0.3 0.0007 19.5 0.0 2.5 1 1 2 3 3 3 3 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EMG48490.1 - 0.13 12.5 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase Adaptin_N PF01602.20 EMG48491.1 - 9.5e-117 390.7 11.0 1.1e-116 390.5 11.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EMG48491.1 - 1e-19 70.9 0.3 2.9e-19 69.4 0.3 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EMG48491.1 - 0.00011 22.3 8.4 0.001 19.1 0.1 3.5 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 ComR_TPR PF18710.1 EMG48491.1 - 0.5 9.9 3.1 0.64 9.5 0.9 2.2 3 0 0 3 3 3 0 ComR tetratricopeptide Ras PF00071.22 EMG48493.1 - 8.5e-56 188.0 0.0 9.8e-56 187.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG48493.1 - 7.4e-22 77.8 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG48493.1 - 2.8e-07 30.1 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMG48493.1 - 0.0027 17.3 0.0 0.0077 15.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EMG48493.1 - 0.0055 16.1 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EMG48493.1 - 0.037 13.4 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EMG48493.1 - 0.057 13.3 0.0 0.2 11.6 0.0 1.9 2 1 0 2 2 2 0 RsgA GTPase C2 PF00168.30 EMG48494.1 - 5.6e-14 52.3 0.0 1.3e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain TRAPPC9-Trs120 PF08626.11 EMG48495.1 - 0.18 9.1 5.3 0.21 8.9 5.3 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Sec10 PF07393.11 EMG48495.1 - 0.52 8.7 6.9 0.67 8.3 6.9 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Macoilin PF09726.9 EMG48495.1 - 2.3 6.7 10.7 2.8 6.4 10.7 1.0 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 EMG48495.1 - 4.1 4.4 9.3 4.4 4.3 9.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MAP65_ASE1 PF03999.12 EMG48495.1 - 7.7 5.1 11.9 8.8 4.9 11.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Hist_deacetyl PF00850.19 EMG48497.1 - 1.3e-80 271.1 0.3 2.3e-80 270.3 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain DUF1256 PF06866.11 EMG48497.1 - 0.035 13.5 0.0 0.25 10.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1256) Pro_CA PF00484.19 EMG48498.1 - 2.8e-10 40.7 0.7 2e-09 37.9 0.7 2.0 1 1 0 1 1 1 1 Carbonic anhydrase Glycos_transf_2 PF00535.26 EMG48499.1 - 3.6e-25 88.7 0.0 4.8e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMG48499.1 - 6.3e-10 39.3 0.0 8.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EMG48499.1 - 0.00011 22.7 0.0 0.00039 20.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EMG48499.1 - 0.002 17.6 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 mRNA_triPase PF02940.15 EMG48500.1 - 8.8e-16 58.3 2.5 1.7e-15 57.4 2.5 1.5 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain PGM_PMM_I PF02878.16 EMG48501.1 - 8e-38 129.3 0.2 1.2e-37 128.7 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EMG48501.1 - 1.2e-24 86.7 0.0 2.6e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EMG48501.1 - 4.5e-14 52.9 0.0 1.1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EMG48501.1 - 2e-09 37.5 0.0 4.6e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GATA PF00320.27 EMG48502.1 - 1.2e-14 53.6 3.1 2.9e-14 52.4 3.1 1.7 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.12 EMG48502.1 - 0.0052 16.6 0.5 1.8 8.5 0.1 2.5 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat TF_Zn_Ribbon PF08271.12 EMG48502.1 - 0.2 11.2 0.3 0.38 10.3 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 EMG48502.1 - 0.27 11.4 0.7 0.48 10.6 0.7 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2387 PF09526.10 EMG48502.1 - 0.58 10.4 0.0 0.58 10.4 0.0 2.5 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) PGA2 PF07543.12 EMG48503.1 - 2.7e-07 30.6 12.3 2.1e-05 24.5 12.3 2.0 1 1 0 1 1 1 1 Protein trafficking PGA2 FAM183 PF14886.6 EMG48503.1 - 0.0061 17.3 0.7 0.0076 17.0 0.7 1.3 1 0 0 1 1 1 1 FAM183A and FAM183B related DUF4483 PF14825.6 EMG48503.1 - 0.011 15.4 5.3 0.014 15.1 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) DUF4376 PF14301.6 EMG48503.1 - 0.027 14.8 3.2 0.042 14.2 3.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4376) Dzip-like_N PF13815.6 EMG48503.1 - 0.04 13.9 0.6 0.04 13.9 0.6 1.9 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF5531 PF17671.1 EMG48503.1 - 0.093 12.6 0.5 0.13 12.1 0.4 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5531) PspB PF06667.12 EMG48503.1 - 0.16 12.0 2.1 0.28 11.3 0.2 2.0 2 0 0 2 2 2 0 Phage shock protein B DUF4834 PF16118.5 EMG48503.1 - 1.1 10.2 5.0 28 5.7 5.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) FinO_N PF12602.8 EMG48503.1 - 5.2 7.5 8.6 0.54 10.6 2.9 2.2 1 1 2 3 3 3 0 Fertility inhibition protein N terminal WD40 PF00400.32 EMG48504.1 - 1.8e-16 60.2 3.4 6.8e-05 23.6 0.3 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG48504.1 - 0.00093 19.4 0.1 0.25 11.7 0.0 3.3 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_3_Rpc31 PF11705.8 EMG48505.1 - 1.5e-46 159.5 13.2 1.8e-46 159.2 13.2 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FANCI_S1-cap PF14674.6 EMG48505.1 - 0.078 13.1 0.3 0.22 11.6 0.3 1.8 1 0 0 1 1 1 0 FANCI solenoid 1 cap BUD22 PF09073.10 EMG48505.1 - 0.19 11.1 12.6 0.26 10.6 12.6 1.2 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 EMG48505.1 - 1.9 8.2 11.9 0.27 11.0 7.3 1.7 1 1 1 2 2 2 0 Ryanodine Receptor TM 4-6 Methyltransf_31 PF13847.6 EMG48506.1 - 3.7e-27 95.0 0.0 5.2e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG48506.1 - 5.1e-24 84.8 0.0 9.4e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG48506.1 - 9.7e-22 77.5 0.0 1.7e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMG48506.1 - 4.9e-15 55.5 0.0 6.5e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EMG48506.1 - 6.5e-15 55.4 0.0 9.8e-15 54.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG48506.1 - 1.7e-12 47.9 0.0 3.5e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMG48506.1 - 9.5e-09 35.3 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EMG48506.1 - 6.5e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EMG48506.1 - 9.3e-05 22.0 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 EMG48506.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_29 PF03141.16 EMG48506.1 - 0.00034 19.3 0.0 0.0005 18.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TehB PF03848.14 EMG48506.1 - 0.00051 19.5 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 EMG48506.1 - 0.0022 17.6 0.0 0.016 14.8 0.0 2.0 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 EMG48506.1 - 0.0033 16.4 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DREV PF05219.12 EMG48506.1 - 0.0083 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.13 EMG48506.1 - 0.048 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 EMG48506.1 - 0.063 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_16 PF10294.9 EMG48506.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase NAS PF03059.16 EMG48506.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein Fungal_trans PF04082.18 EMG48507.1 - 5.5e-09 35.4 0.0 2.7e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG48507.1 - 1.3e-07 31.6 9.5 1.3e-07 31.6 9.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med5 PF08689.10 EMG48508.1 - 1.6e-57 195.2 69.2 1.2e-55 189.0 23.7 3.1 2 1 1 3 3 3 3 Mediator complex subunit Med5 CdiI_2 PF18593.1 EMG48508.1 - 0.048 14.3 1.7 8.4 7.1 0.1 3.6 3 0 0 3 3 3 0 CdiI immunity protein SART-1 PF03343.13 EMG48509.1 - 0.093 11.3 22.2 0.13 10.8 22.2 1.1 1 0 0 1 1 1 0 SART-1 family Med15 PF09606.10 EMG48509.1 - 0.49 9.0 51.3 0.62 8.7 51.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.13 EMG48509.1 - 1.4 7.9 36.7 0.085 11.9 31.4 1.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.13 EMG48510.1 - 1.7e-37 129.5 0.4 1.7e-37 129.5 0.4 3.1 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Tup_N PF08581.10 EMG48510.1 - 0.022 15.0 3.6 0.022 15.0 3.6 2.4 1 1 1 2 2 2 0 Tup N-terminal Baculo_PEP_C PF04513.12 EMG48510.1 - 0.088 12.8 8.6 0.17 11.9 8.6 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mt_ATP-synt_D PF05873.12 EMG48510.1 - 0.83 9.5 13.7 0.15 11.9 5.0 3.3 3 1 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1640 PF07798.11 EMG48510.1 - 2.3 8.2 11.6 0.13 12.3 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Golgin_A5 PF09787.9 EMG48510.1 - 5 6.5 14.3 0.29 10.5 8.5 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 CAP18_C PF12153.8 EMG48510.1 - 6 6.8 7.0 1.2 9.1 1.9 2.5 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) CCDC84 PF14968.6 EMG48510.1 - 7.5 6.1 13.7 1.1 8.8 9.2 1.9 2 1 0 2 2 2 0 Coiled coil protein 84 Mito_carr PF00153.27 EMG48511.1 - 1.6e-46 156.2 0.5 5.8e-16 58.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3506 PF12014.8 EMG48511.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Prenyltrans PF00432.21 EMG48512.1 - 4.7e-25 87.0 4.4 7.6e-09 35.2 0.0 5.8 5 1 1 6 6 6 4 Prenyltransferase and squalene oxidase repeat Fer2_3 PF13085.6 EMG48515.1 - 8.9e-33 112.6 0.1 1.5e-32 111.9 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EMG48515.1 - 2.9e-09 37.3 7.4 2.9e-09 37.3 7.4 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EMG48515.1 - 1.7e-07 31.6 8.5 1.7e-07 31.6 8.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMG48515.1 - 2.8e-07 30.5 3.6 2.8e-07 30.5 3.6 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EMG48515.1 - 0.0035 17.3 0.9 0.0035 17.3 0.9 2.7 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 EMG48515.1 - 0.021 15.4 8.6 0.021 15.4 8.6 3.0 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EMG48515.1 - 0.28 11.4 12.7 0.24 11.6 8.6 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain ABC_tran_Xtn PF12848.7 EMG48516.1 - 0.0099 15.9 1.8 0.016 15.2 1.8 1.3 1 0 0 1 1 1 1 ABC transporter DUF16 PF01519.16 EMG48516.1 - 0.039 14.4 0.7 0.079 13.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 MerR-DNA-bind PF09278.11 EMG48516.1 - 0.074 13.6 1.7 0.11 13.0 1.7 1.3 1 0 0 1 1 1 0 MerR, DNA binding Latarcin PF10279.9 EMG48516.1 - 0.097 13.1 0.5 0.17 12.3 0.5 1.4 1 0 0 1 1 1 0 Latarcin precursor YvrJ PF12841.7 EMG48516.1 - 0.2 11.2 0.4 0.38 10.3 0.4 1.5 1 0 0 1 1 1 0 YvrJ protein family FliD_N PF02465.18 EMG48516.1 - 0.27 11.9 1.4 0.74 10.6 1.4 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus MCRS_N PF13325.6 EMG48516.1 - 0.44 10.5 3.9 0.36 10.8 2.0 1.8 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein hNIFK_binding PF12196.8 EMG48517.1 - 0.41 10.2 4.3 0.46 10.0 2.5 2.0 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK PTPLA PF04387.14 EMG48518.1 - 3.2e-18 66.0 7.6 6.6e-18 65.0 7.6 1.5 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SAPS PF04499.15 EMG48519.1 - 2.9e-162 540.9 7.2 2.9e-162 540.9 7.2 3.2 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein DUF4709 PF15821.5 EMG48519.1 - 0.088 13.1 0.5 0.32 11.3 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) Post_transc_reg PF13797.6 EMG48519.1 - 0.12 12.2 0.6 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Post-transcriptional regulator BIR PF00653.21 EMG48520.1 - 1.6e-28 99.2 1.4 2.3e-17 63.4 0.2 2.7 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-BED PF02892.15 EMG48520.1 - 0.0039 17.2 3.0 1.2 9.2 0.2 2.6 2 0 0 2 2 2 2 BED zinc finger Sugar_tr PF00083.24 EMG48521.1 - 3.8e-105 352.4 27.0 4.9e-105 352.0 27.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG48521.1 - 4.2e-27 95.0 48.2 1.2e-18 67.2 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMG48521.1 - 8.5e-05 21.2 2.1 8.5e-05 21.2 2.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EMG48521.1 - 0.0044 15.6 7.1 0.0044 15.6 7.1 3.2 2 2 1 3 3 3 1 MFS/sugar transport protein RhodobacterPufX PF11511.8 EMG48521.1 - 0.45 10.2 6.7 21 4.8 0.1 3.3 2 0 0 2 2 2 0 Intrinsic membrane protein PufX 2-Hacid_dh_C PF02826.19 EMG48522.1 - 1.7e-34 118.8 0.0 7.9e-34 116.6 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMG48522.1 - 8.9e-17 61.0 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 EMG48522.1 - 0.0058 16.0 0.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EMG48522.1 - 0.045 13.8 0.0 0.29 11.2 0.0 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RAI1 PF08652.11 EMG48523.1 - 1.4e-14 54.0 0.0 4.5e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease AA_permease PF00324.21 EMG48524.1 - 6.5e-79 265.7 48.4 7.8e-79 265.5 48.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG48524.1 - 3.5e-29 101.9 54.7 5.3e-29 101.3 54.4 1.4 1 1 0 1 1 1 1 Amino acid permease MdcG PF10620.9 EMG48524.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Gln-synt_C PF00120.24 EMG48525.1 - 7.4e-19 67.9 0.0 1.4e-17 63.7 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EMG48525.1 - 1.5e-10 40.7 0.0 2.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain REF PF05755.12 EMG48526.1 - 0.091 12.6 0.9 6 6.6 0.1 2.0 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) FRG PF08867.11 EMG48527.1 - 0.15 13.0 0.3 0.15 13.0 0.3 2.9 2 0 0 2 2 2 0 FRG domain Baculo_PEP_C PF04513.12 EMG48527.1 - 0.49 10.4 6.8 0.47 10.5 0.5 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FGGY_C PF02782.16 EMG48528.1 - 1.2e-68 230.8 0.3 2.4e-68 229.8 0.2 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EMG48528.1 - 1.4e-54 185.2 0.1 9.3e-46 156.4 0.0 3.1 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain ROK PF00480.20 EMG48528.1 - 0.12 11.8 0.1 0.73 9.3 0.0 2.0 2 0 0 2 2 2 0 ROK family KxDL PF10241.9 EMG48529.1 - 4.4 7.7 16.0 5.6 7.3 2.8 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein IPK PF03770.16 EMG48530.1 - 1.7e-49 168.4 0.0 1.7e-49 168.4 0.0 1.7 2 0 0 2 2 2 1 Inositol polyphosphate kinase Clat_adaptor_s PF01217.20 EMG48531.1 - 2e-52 176.9 4.1 2.3e-52 176.7 4.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CNOT1_HEAT PF16418.5 EMG48531.1 - 0.017 15.2 0.3 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Mannosyl_trans3 PF11051.8 EMG48532.1 - 4e-83 278.9 0.0 1.1e-82 277.5 0.0 1.8 2 0 0 2 2 2 1 Mannosyltransferase putative Presenilin PF01080.17 EMG48532.1 - 2.9 6.6 3.8 5.3 5.7 3.8 1.4 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 EMG48532.1 - 4.7 7.3 10.2 7.4 6.7 10.2 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated ADH_N PF08240.12 EMG48536.1 - 3.1e-28 97.8 4.2 5.1e-28 97.1 4.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMG48536.1 - 1.7e-11 44.2 0.0 2.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMG48536.1 - 6.2e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus DAO PF01266.24 EMG48536.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF4718 PF15842.5 EMG48537.1 - 0.23 11.2 4.8 0.068 13.0 2.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4718) FMN_red PF03358.15 EMG48539.1 - 4.1e-09 36.4 0.0 9.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMG48539.1 - 0.0042 16.8 0.1 0.014 15.1 0.1 1.8 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 EMG48539.1 - 0.0096 16.2 0.0 0.17 12.2 0.0 2.3 2 1 0 2 2 2 1 Flavodoxin domain Spore_coat_CotO PF14153.6 EMG48539.1 - 1.8 8.5 5.3 2.6 8.0 5.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO zf-RING_2 PF13639.6 EMG48540.1 - 9.7e-11 41.8 5.9 1.8e-10 41.0 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EMG48540.1 - 1.8e-07 30.8 3.3 4.1e-07 29.6 3.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EMG48540.1 - 1.9e-07 30.8 5.8 3.5e-07 30.0 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMG48540.1 - 2.1e-07 30.7 5.8 3.7e-07 29.9 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMG48540.1 - 2.2e-07 31.0 4.3 5.6e-07 29.7 4.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EMG48540.1 - 6.2e-07 29.3 4.6 1.1e-06 28.5 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EMG48540.1 - 6.4e-05 22.7 3.8 0.00014 21.6 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG48540.1 - 0.00043 20.3 6.4 0.0011 19.0 6.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EMG48540.1 - 0.00059 19.8 1.0 0.0012 18.8 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EMG48540.1 - 0.00088 19.1 4.4 0.0018 18.1 4.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EMG48540.1 - 0.0027 17.3 2.7 0.0056 16.3 2.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EMG48540.1 - 0.33 11.1 5.0 0.65 10.2 5.0 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 EMG48540.1 - 0.39 10.8 4.7 1.3 9.1 4.7 2.0 1 0 0 1 1 1 0 Zinc-finger zf-Nse PF11789.8 EMG48540.1 - 0.54 10.1 3.6 1.1 9.1 3.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 EMG48540.1 - 0.94 9.7 7.1 2.7 8.2 5.7 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain Noc2 PF03715.13 EMG48541.1 - 5.3e-129 429.7 4.5 5.3e-129 429.7 4.5 2.4 2 0 0 2 2 2 1 Noc2p family Zn_clus PF00172.18 EMG48542.1 - 1.8e-05 24.8 6.5 3.5e-05 23.8 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCSAP PF15748.5 EMG48542.1 - 0.0068 16.6 16.2 0.0068 16.6 16.2 3.1 2 1 0 2 2 2 1 Centriole, cilia and spindle-associated Ndc1_Nup PF09531.10 EMG48542.1 - 3.8 6.1 35.1 1.8 7.2 17.8 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Glutaredoxin PF00462.24 EMG48543.1 - 0.00063 19.9 0.1 0.00095 19.3 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF1462 PF07315.11 EMG48543.1 - 0.17 12.2 1.1 0.21 11.9 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1462) XPG_N PF00752.17 EMG48544.1 - 0.038 14.4 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 XPG N-terminal domain Mito_carr PF00153.27 EMG48545.1 - 5.1e-62 205.8 2.1 8.8e-23 80.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RIIa PF02197.17 EMG48545.1 - 0.09 12.5 0.0 9.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit ADH_N PF08240.12 EMG48546.1 - 1.9e-25 88.9 4.0 3.5e-25 88.0 4.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMG48546.1 - 1.6e-15 57.2 0.0 2.7e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMG48546.1 - 1e-06 28.4 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus DAO PF01266.24 EMG48546.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EMG48546.1 - 0.048 12.9 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N_2 PF13602.6 EMG48546.1 - 0.11 13.6 0.0 0.2 12.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 EMG48546.1 - 0.13 12.5 0.4 0.92 9.8 0.2 2.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DUF2407_C PF13373.6 EMG48547.1 - 4.9e-46 156.4 0.0 7.3e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EMG48547.1 - 9.7e-18 64.7 2.0 4.4e-15 56.1 0.1 2.5 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMG48547.1 - 0.033 14.3 0.2 0.051 13.7 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EMG48547.1 - 0.042 13.6 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Gcd10p PF04189.13 EMG48547.1 - 0.11 11.6 0.1 0.21 10.7 0.1 1.4 1 0 0 1 1 1 0 Gcd10p family MTP18 PF10558.9 EMG48548.1 - 6.5e-73 244.3 0.2 7.7e-73 244.1 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) 3-HAO PF06052.12 EMG48549.1 - 1.2e-65 219.8 0.1 1.4e-65 219.6 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EMG48549.1 - 2.2e-06 27.3 0.1 3.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Cupin domain DZR PF12773.7 EMG48549.1 - 0.024 14.7 0.7 0.08 13.0 0.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon YhfH PF14149.6 EMG48549.1 - 0.059 13.3 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 YhfH-like protein Rpr2 PF04032.16 EMG48549.1 - 0.13 12.5 0.3 0.96 9.8 0.4 2.0 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cupin_1 PF00190.22 EMG48549.1 - 0.19 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Cupin zf-ribbon_3 PF13248.6 EMG48549.1 - 0.21 11.1 2.8 0.82 9.2 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RanBP PF00641.18 EMG48549.1 - 0.48 9.8 5.4 2.6 7.4 0.4 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Glutaredoxin PF00462.24 EMG48550.1 - 0.011 15.9 0.8 0.033 14.4 0.1 2.1 3 0 0 3 3 3 0 Glutaredoxin IL17R_fnIII_D1 PF16556.5 EMG48550.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Interleukin-17 receptor, fibronectin-III-like domain 1 Haemocyan_bet_s PF14830.6 EMG48551.1 - 0.079 13.0 0.1 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 Haemocyanin beta-sandwich Hepsin-SRCR PF09272.10 EMG48551.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Hepsin, SRCR domain DUF4928 PF16280.5 EMG48552.1 - 0.048 12.9 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) TFIIB PF00382.19 EMG48553.1 - 7.7e-33 112.4 0.1 4.9e-18 64.9 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EMG48553.1 - 4.1e-13 48.6 0.6 8.2e-13 47.6 0.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Trp_repressor PF01371.19 EMG48553.1 - 0.0011 19.0 1.0 0.047 13.8 0.1 2.4 2 0 0 2 2 2 1 Trp repressor protein Cyclin_C PF02984.19 EMG48553.1 - 0.0057 16.7 0.0 0.12 12.4 0.0 2.6 1 1 1 2 2 2 1 Cyclin, C-terminal domain EcoR124_C PF12008.8 EMG48553.1 - 0.024 14.3 0.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal zf-ribbon_3 PF13248.6 EMG48553.1 - 0.11 11.9 3.7 2.3 7.7 3.7 2.4 1 1 0 1 1 1 0 zinc-ribbon domain AOC_like PF18678.1 EMG48553.1 - 0.12 12.0 0.1 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Allene oxide cyclase barrel like domain DPPIV_N PF00930.21 EMG48554.1 - 1.9e-65 220.9 10.3 3.2e-65 220.2 10.3 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EMG48554.1 - 3.1e-46 157.5 0.0 5.5e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 EMG48554.1 - 0.0016 17.0 0.0 0.0032 16.0 0.0 1.4 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 EMG48554.1 - 0.0017 19.0 0.0 0.014 16.0 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMG48554.1 - 0.0018 17.9 0.2 0.0099 15.5 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 EMG48554.1 - 0.0022 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase RNA_pol_Rpb2_6 PF00562.28 EMG48555.1 - 2.6e-122 408.7 0.9 2.9e-122 408.5 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EMG48555.1 - 2.7e-59 200.1 0.8 4.1e-59 199.5 0.8 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EMG48555.1 - 4.2e-39 134.1 1.8 8.1e-39 133.2 1.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EMG48555.1 - 1.4e-34 118.4 0.1 3.4e-34 117.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EMG48555.1 - 5e-27 94.0 0.4 1.9e-26 92.1 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EMG48555.1 - 1.9e-18 66.4 0.0 4.4e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EMG48555.1 - 3.8e-13 49.8 0.2 1.1e-12 48.3 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 TraI_2_C PF07515.11 EMG48555.1 - 0.084 12.8 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term Ribonuc_red_lgC PF02867.15 EMG48557.1 - 1.2e-183 611.5 0.0 1.5e-183 611.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EMG48557.1 - 2.3e-22 78.8 0.1 1.2e-21 76.5 0.1 2.2 3 0 0 3 3 3 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EMG48557.1 - 1.8e-06 28.5 0.4 6.3e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 ATP cone domain Tfb2 PF03849.14 EMG48558.1 - 1.1e-142 475.3 0.9 1.5e-142 474.8 0.9 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EMG48558.1 - 4.2e-22 78.3 0.5 8.7e-22 77.3 0.5 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EMG48558.1 - 0.00013 22.1 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SDA1 PF05285.12 EMG48560.1 - 3.5e-101 339.1 40.4 5.5e-101 338.5 33.3 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EMG48560.1 - 7.1e-25 87.1 0.9 4.1e-24 84.7 0.1 2.7 3 0 0 3 3 3 1 NUC130/3NT domain EF-hand_14 PF17959.1 EMG48560.1 - 0.055 13.8 0.0 0.27 11.6 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain TFIIB PF00382.19 EMG48561.1 - 3e-52 174.6 1.5 1.7e-26 92.0 0.2 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EMG48561.1 - 1.2e-23 83.3 4.5 1.2e-23 83.3 4.5 2.6 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EMG48561.1 - 2.5e-10 39.7 0.9 4.5e-10 38.9 0.9 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EMG48561.1 - 6.8e-05 22.6 0.3 0.23 11.2 0.1 2.9 2 0 0 2 2 2 2 Cyclin, N-terminal domain DZR PF12773.7 EMG48561.1 - 0.11 12.6 0.7 0.21 11.6 0.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EMG48561.1 - 0.3 11.2 0.8 0.79 9.9 0.8 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 EMG48561.1 - 0.4 10.7 2.9 10 6.2 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 EMG48561.1 - 0.65 9.8 1.9 10 6.0 0.3 2.7 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.6 EMG48561.1 - 1.1 9.0 3.2 8.8 6.2 2.7 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zf-RRN7 PF11781.8 EMG48561.1 - 1.2 8.9 3.0 10 5.9 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 FYDLN_acid PF09538.10 EMG48561.1 - 1.3 9.7 0.0 1.3 9.7 0.0 3.6 2 1 0 2 2 1 0 Protein of unknown function (FYDLN_acid) zf-HYPF PF07503.12 EMG48561.1 - 1.5 8.6 4.1 0.84 9.5 1.0 2.1 2 0 0 2 2 2 0 HypF finger DUF202 PF02656.15 EMG48562.1 - 1.3e-08 35.2 0.0 1.6e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DEAD PF00270.29 EMG48563.1 - 7e-44 149.7 0.0 2e-43 148.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG48563.1 - 3.2e-30 104.7 0.3 1.9e-29 102.2 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG48563.1 - 3.6e-06 27.1 0.2 2.1e-05 24.6 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EMG48563.1 - 0.081 13.2 0.1 0.27 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain SecA_DEAD PF07517.14 EMG48563.1 - 0.18 11.0 4.2 3.6 6.8 0.1 3.0 2 1 0 2 2 2 0 SecA DEAD-like domain GTP1_OBG PF01018.22 EMG48564.1 - 1.1e-35 122.5 0.7 1e-24 86.9 0.5 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EMG48564.1 - 2.8e-22 79.0 0.0 8.8e-22 77.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMG48564.1 - 6.7e-08 32.2 0.0 1.3e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 EMG48564.1 - 4.9e-05 22.8 0.0 0.00016 21.2 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 EMG48564.1 - 0.035 14.2 0.3 6.9 6.7 0.0 3.0 2 1 1 3 3 3 0 Dynamin family Response_reg PF00072.24 EMG48565.1 - 8e-15 55.0 0.1 1.3e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain PUFD PF16553.5 EMG48565.1 - 0.033 14.3 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain Cwf_Cwc_15 PF04889.12 EMG48565.1 - 0.11 12.2 12.0 0.16 11.7 12.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 EMG48565.1 - 0.11 12.9 11.3 0.21 12.0 11.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HEXIM PF15313.6 EMG48565.1 - 0.24 11.6 5.3 0.39 10.9 5.3 1.3 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein FAM176 PF14851.6 EMG48565.1 - 0.29 10.8 1.8 0.48 10.1 1.8 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EMG48565.1 - 2.4 7.4 9.8 3.4 6.9 9.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2076 PF09849.9 EMG48565.1 - 8.4 6.4 10.0 11 5.9 10.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Glyco_transf_20 PF00982.21 EMG48566.1 - 1.9e-204 679.7 0.0 2.2e-204 679.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 EMG48566.1 - 4.3e-05 23.1 0.4 0.0091 15.5 0.0 2.7 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EMG48566.1 - 0.039 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain YIF1 PF03878.15 EMG48567.1 - 1.1e-59 201.9 1.4 1.1e-59 201.9 1.4 1.7 2 0 0 2 2 2 1 YIF1 Yip1 PF04893.17 EMG48567.1 - 0.0052 16.5 0.1 0.0085 15.8 0.1 1.3 1 0 0 1 1 1 1 Yip1 domain EPL1 PF10513.9 EMG48567.1 - 0.1 13.0 5.5 0.12 12.7 5.5 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like SARAF PF06682.12 EMG48567.1 - 0.32 10.6 6.1 0.37 10.4 6.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TFIIA PF03153.13 EMG48567.1 - 3.1 7.7 27.5 4 7.3 27.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EMG48567.1 - 3.3 5.8 17.9 4.1 5.6 17.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.10 EMG48567.1 - 3.6 6.2 25.9 4.1 6.0 25.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Acyl_transf_1 PF00698.21 EMG48568.1 - 1.3e-15 57.7 0.0 1.7e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain ROK PF00480.20 EMG48568.1 - 0.058 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 ROK family SAT PF16073.5 EMG48568.1 - 0.16 11.7 1.7 2.8 7.6 0.1 2.4 1 1 1 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis HMG_box PF00505.19 EMG48569.1 - 6.8e-07 29.6 2.7 6.8e-07 29.6 2.7 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box DUF2924 PF11149.8 EMG48569.1 - 1.4 9.3 5.4 2 8.8 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2924) Coilin_N PF15862.5 EMG48569.1 - 5.7 6.7 14.0 1.1 9.1 6.5 2.4 2 0 0 2 2 2 0 Coilin N-terminus Vezatin PF12632.7 EMG48571.1 - 1.3e-41 142.8 19.1 1.3e-41 142.8 19.1 3.0 2 1 0 2 2 2 1 Mysoin-binding motif of peroxisomes LisH PF08513.11 EMG48572.1 - 7.5e-05 22.5 0.6 0.00013 21.8 0.6 1.4 1 0 0 1 1 1 1 LisH F-box-like PF12937.7 EMG48573.1 - 8.7e-06 25.5 0.7 4.6e-05 23.2 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EMG48573.1 - 0.0046 16.8 0.1 0.013 15.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EMG48573.1 - 0.014 15.3 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 F-box Aldedh PF00171.22 EMG48574.1 - 4e-180 599.3 1.1 4.5e-180 599.1 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EMG48574.1 - 0.0066 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Beta_elim_lyase PF01212.21 EMG48575.1 - 1.9e-77 260.4 0.0 2.3e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EMG48575.1 - 1.3e-06 27.8 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMG48575.1 - 0.053 12.8 0.1 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family 2-Hacid_dh_C PF02826.19 EMG48576.1 - 2.8e-09 36.6 0.0 2.7e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EMG48576.1 - 0.092 11.9 0.0 0.098 11.8 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh PF00389.30 EMG48577.1 - 1.9e-17 63.2 0.0 2.1e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain UDPGP PF01704.18 EMG48578.1 - 6.5e-187 621.2 0.0 7.6e-187 621.0 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase TBCA PF02970.16 EMG48579.1 - 1.5e-25 89.3 14.7 1.8e-25 89.1 14.7 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A NusB PF01029.18 EMG48579.1 - 0.012 15.8 3.8 0.015 15.6 3.8 1.1 1 0 0 1 1 1 0 NusB family CENP-K PF11802.8 EMG48579.1 - 0.014 15.0 7.6 0.015 14.8 7.6 1.0 1 0 0 1 1 1 0 Centromere-associated protein K PSII_Pbs27 PF13326.6 EMG48579.1 - 0.015 15.6 2.8 0.043 14.2 2.7 1.6 1 1 0 1 1 1 0 Photosystem II Pbs27 TSKS PF15358.6 EMG48579.1 - 0.032 12.6 1.6 0.039 12.3 1.3 1.3 1 1 0 1 1 1 0 Testis-specific serine kinase substrate FapA PF03961.13 EMG48579.1 - 0.041 12.5 8.4 0.045 12.4 8.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Phage_GP20 PF06810.11 EMG48579.1 - 0.073 12.9 11.6 0.18 11.6 11.6 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 WHEP-TRS PF00458.20 EMG48579.1 - 0.083 13.1 3.5 0.35 11.1 3.5 2.1 1 1 0 1 1 1 0 WHEP-TRS domain Ribosomal_L13 PF00572.18 EMG48579.1 - 0.13 12.5 2.5 0.15 12.3 2.5 1.0 1 0 0 1 1 1 0 Ribosomal protein L13 DUF1501 PF07394.12 EMG48579.1 - 0.24 10.4 0.9 0.22 10.5 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) HSP70 PF00012.20 EMG48579.1 - 0.33 9.1 7.5 0.33 9.1 7.5 1.0 1 0 0 1 1 1 0 Hsp70 protein PAP_central PF04928.17 EMG48579.1 - 0.47 9.4 2.9 0.51 9.3 2.9 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain U1snRNP70_N PF12220.8 EMG48579.1 - 0.92 10.2 7.3 1.3 9.7 7.3 1.3 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2570 PF10828.8 EMG48579.1 - 4.5 7.1 10.4 14 5.5 10.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DIT1_PvcA PF05141.12 EMG48580.1 - 1.5e-96 323.1 0.0 1.9e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.22 EMG48581.1 - 6.1e-45 153.8 0.0 2.3e-44 152.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_A2E PF12382.8 EMG48581.1 - 0.066 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon peptidase MFS_1 PF07690.16 EMG48582.1 - 8.6e-44 149.9 31.4 8.6e-44 149.9 31.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG48582.1 - 4e-17 62.2 26.0 2.5e-16 59.6 26.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.8 EMG48583.1 - 1.6e-131 439.2 24.8 3e-131 438.3 24.8 1.4 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like CTV_P6 PF06706.11 EMG48583.1 - 2.4 7.9 6.1 0.54 10.0 1.3 2.4 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Cupin_8 PF13621.6 EMG48584.1 - 6.9e-13 48.9 1.5 7.1e-13 48.9 0.1 1.7 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 EMG48584.1 - 7.9e-10 39.2 0.7 2.9e-08 34.1 0.7 2.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 EMG48584.1 - 1e-08 34.9 0.1 3.3e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EMG48584.1 - 0.00012 21.9 0.0 0.00044 20.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EMG48584.1 - 0.027 15.0 3.6 1.3 9.5 0.3 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A ALMS_motif PF15309.6 EMG48584.1 - 0.039 14.4 0.3 0.11 13.0 0.3 1.7 1 0 0 1 1 1 0 ALMS motif 2-Hacid_dh_C PF02826.19 EMG48585.1 - 2.8e-09 36.6 0.0 2.7e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EMG48585.1 - 0.092 11.9 0.0 0.098 11.8 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh PF00389.30 EMG48586.1 - 1.9e-17 63.2 0.0 2.1e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Ndc80_HEC PF03801.13 EMG48587.1 - 1.3e-42 145.0 1.7 1.3e-42 145.0 1.7 2.2 2 0 0 2 2 2 1 HEC/Ndc80p family GIT_CC PF16559.5 EMG48587.1 - 0.014 15.3 2.1 0.014 15.3 2.1 3.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2703 PF10865.8 EMG48587.1 - 0.15 12.3 6.2 0.093 12.9 1.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) DUF1512 PF07431.12 EMG48587.1 - 10 5.0 11.5 0.65 8.9 4.8 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1512) Ubiquitin_2 PF14560.6 EMG48588.1 - 6.4e-27 93.8 0.1 1.2e-26 92.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 EMG48588.1 - 2.3e-22 78.8 1.2 3.4e-22 78.2 1.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 EMG48588.1 - 0.063 13.0 0.1 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family Glyco_hydro_2 PF00703.21 EMG48589.1 - 2.9e-08 34.3 0.0 7.2e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 EMG48589.1 - 0.00026 21.5 0.0 0.00072 20.1 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_C PF02836.17 EMG48589.1 - 0.068 12.3 0.1 0.6 9.2 0.1 2.1 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF2959 PF11172.8 EMG48590.1 - 0.13 12.4 0.2 0.24 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) OPT PF03169.15 EMG48591.1 - 1.6e-161 539.0 40.6 1.9e-161 538.8 40.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 EMG48592.1 - 6.6e-160 533.7 39.3 7.6e-160 533.5 39.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4405 PF14358.6 EMG48592.1 - 9.8 6.8 11.5 17 6.0 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) RNA_pol_Rpc82 PF05645.13 EMG48593.1 - 1.8e-63 214.7 0.1 3.2e-63 213.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EMG48593.1 - 3.1e-20 72.0 0.6 3.5e-19 68.6 0.2 2.6 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EMG48593.1 - 3.8e-07 29.9 1.3 0.0022 17.8 0.0 3.2 3 0 0 3 3 3 2 TFIIE alpha subunit TrmB PF01978.19 EMG48593.1 - 0.0018 18.1 0.1 0.028 14.3 0.0 2.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EMG48593.1 - 0.012 15.2 3.2 0.023 14.3 1.4 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MIP PF00230.20 EMG48595.1 - 2.9e-42 144.9 15.2 3.6e-42 144.6 15.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein LMBR1 PF04791.16 EMG48595.1 - 8.7 5.1 6.1 0.96 8.3 1.8 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein ATG13 PF10033.9 EMG48596.1 - 3.6e-72 242.9 1.7 3.6e-72 242.9 1.7 1.8 2 0 0 2 2 2 1 Autophagy-related protein 13 DUF4378 PF14309.6 EMG48596.1 - 0.053 13.9 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) DUF5571 PF17732.1 EMG48596.1 - 0.086 12.3 10.5 0.36 10.2 2.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5571) SRP40_C PF05022.12 EMG48597.1 - 1.9e-24 86.3 2.8 5.6e-24 84.8 2.8 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain dsrm PF00035.26 EMG48598.1 - 1.8e-10 41.3 7.6 1.7e-07 31.9 0.1 3.1 3 0 0 3 3 3 2 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 EMG48598.1 - 3.8e-06 27.1 0.0 6.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Pex14_N PF04695.13 EMG48598.1 - 2.2 8.9 12.8 5.7 7.6 12.8 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 EMG48598.1 - 4 7.3 12.7 5.6 6.9 12.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ERCC3_RAD25_C PF16203.5 EMG48599.1 - 1.1e-125 417.8 1.2 1.1e-125 417.8 1.2 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EMG48599.1 - 7.4e-37 126.3 0.1 2.1e-36 124.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG48599.1 - 1.6e-15 57.6 0.0 1.6e-15 57.6 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMG48599.1 - 1.1e-12 48.3 0.1 2.7e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EMG48599.1 - 5.1e-09 35.3 0.0 6.6e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EMG48599.1 - 5.2e-06 26.3 0.0 1.4e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.6 EMG48599.1 - 0.032 13.7 0.3 0.093 12.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein AAA_22 PF13401.6 EMG48599.1 - 0.09 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain BRF1 PF07741.13 EMG48599.1 - 0.36 11.2 6.6 2.1 8.7 4.8 2.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Ribosomal_S21 PF01165.20 EMG48601.1 - 7.2e-11 41.6 5.5 1.3e-10 40.8 5.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Mito_carr PF00153.27 EMG48602.1 - 7.9e-42 141.1 1.7 4.9e-16 58.4 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Gtr1_RagA PF04670.12 EMG48604.1 - 2.7e-53 180.7 0.8 4.4e-53 180.0 0.8 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region eRF1_1 PF03463.15 EMG48605.1 - 2.3e-30 105.2 1.8 3.6e-30 104.6 1.8 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EMG48605.1 - 3.9e-24 85.3 0.0 1.3e-23 83.6 0.0 2.0 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EMG48605.1 - 1.4e-23 83.7 0.1 2.4e-23 82.9 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 tRNA_bind PF01588.20 EMG48606.1 - 2.5e-27 94.8 0.6 5.2e-27 93.8 0.1 1.8 2 0 0 2 2 2 1 Putative tRNA binding domain GST_C_3 PF14497.6 EMG48606.1 - 0.2 11.9 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain BORG_CEP PF14957.6 EMG48606.1 - 0.25 12.5 2.3 0.63 11.2 0.5 2.1 2 0 0 2 2 2 0 Cdc42 effector NARP1 PF12569.8 EMG48606.1 - 0.99 8.2 9.2 1.3 7.8 9.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Mitofilin PF09731.9 EMG48606.1 - 1.4 7.6 15.7 2.5 6.8 15.7 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RR_TM4-6 PF06459.12 EMG48606.1 - 3.3 7.5 12.6 1 9.1 9.7 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EMG48606.1 - 7.1 5.3 6.0 11 4.7 6.0 1.2 1 0 0 1 1 1 0 Presenilin PAS PF00989.25 EMG48607.1 - 9.5e-07 28.8 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 EMG48607.1 - 5e-06 26.5 13.1 1.1e-05 25.5 13.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.7 EMG48607.1 - 0.13 12.5 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 PAS domain Sugar_tr PF00083.24 EMG48608.1 - 9e-88 295.1 15.9 1.4e-87 294.5 15.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG48608.1 - 2.2e-27 95.9 27.3 2.5e-27 95.7 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EMG48608.1 - 2e-06 27.0 1.1 2e-06 27.0 1.1 2.5 3 0 0 3 3 3 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 EMG48608.1 - 3e-06 25.9 2.7 3e-06 25.9 2.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EMG48608.1 - 8.8e-06 25.2 2.6 8.8e-06 25.2 2.6 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PrgU PF09627.10 EMG48608.1 - 0.072 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 PrgU-like protein Ribosomal_L27A PF00828.19 EMG48609.1 - 9.4e-22 78.0 0.1 9.4e-22 78.0 0.1 1.8 1 1 1 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HD_3 PF13023.6 EMG48610.1 - 5.9e-38 130.4 0.0 7.5e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EMG48610.1 - 1.8e-07 31.1 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EMG48610.1 - 0.00012 22.2 0.1 0.00033 20.9 0.1 1.7 1 1 0 1 1 1 1 HD domain Evr1_Alr PF04777.13 EMG48611.1 - 2.7e-31 108.0 4.3 2.7e-31 108.0 4.3 1.5 2 0 0 2 2 2 1 Erv1 / Alr family FANCL_C PF11793.8 EMG48612.1 - 0.16 12.1 0.1 1.7 8.9 0.0 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain GTP_cyclohydro2 PF00925.20 EMG48613.1 - 6e-59 198.3 0.0 8.3e-59 197.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II tRNA-synt_2 PF00152.20 EMG48614.1 - 5.2e-80 268.9 0.4 7.7e-80 268.3 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMG48614.1 - 1e-07 31.8 0.6 2e-07 30.9 0.6 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMG48614.1 - 0.047 13.2 0.5 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) FAM178 PF14816.6 EMG48614.1 - 0.056 12.4 0.8 0.091 11.7 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 TYW3 PF02676.14 EMG48615.1 - 2.6e-48 164.2 0.0 4.1e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 PHM7_cyt PF14703.6 EMG48615.1 - 0.023 14.9 2.3 0.047 13.9 2.3 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter GRIP PF01465.20 EMG48616.1 - 2.4e-14 52.9 0.1 6.4e-14 51.6 0.1 1.8 1 0 0 1 1 1 1 GRIP domain UPF0242 PF06785.11 EMG48616.1 - 0.00019 21.6 19.2 0.00019 21.6 19.2 7.4 2 2 6 8 8 7 3 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EMG48616.1 - 0.0002 20.4 142.6 0.00088 18.2 15.1 7.1 1 1 6 7 7 7 3 Spc7 kinetochore protein ATG16 PF08614.11 EMG48616.1 - 0.0024 18.1 145.6 0.0046 17.2 8.4 9.5 2 1 6 9 9 8 6 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EMG48616.1 - 0.0046 17.0 15.4 0.0046 17.0 15.4 9.0 1 1 6 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 EMG48616.1 - 0.0056 16.9 6.0 0.0056 16.9 6.0 9.6 2 1 7 10 10 10 4 TATA element modulatory factor 1 TATA binding DUF3287 PF11690.8 EMG48616.1 - 0.0063 16.2 10.8 0.018 14.8 0.1 4.4 4 1 0 4 4 4 2 Protein of unknown function (DUF3287) Tropomyosin_1 PF12718.7 EMG48616.1 - 0.008 16.3 20.1 0.008 16.3 20.1 8.0 2 1 6 8 8 7 2 Tropomyosin like BRE1 PF08647.11 EMG48616.1 - 0.008 16.2 9.5 0.008 16.2 9.5 10.4 4 2 7 12 12 11 2 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.11 EMG48616.1 - 0.018 15.5 4.3 0.018 15.5 4.3 11.7 8 3 5 13 13 13 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 EMG48616.1 - 0.018 15.1 131.9 0.099 12.7 9.8 8.8 3 2 1 6 6 6 0 TPR/MLP1/MLP2-like protein TFA2_Winged_2 PF18121.1 EMG48616.1 - 3.3 7.5 22.7 0.58 9.9 0.7 6.3 6 0 0 6 6 6 0 TFA2 Winged helix domain 2 Filament PF00038.21 EMG48616.1 - 6.4 6.3 116.3 11 5.4 6.9 5.9 1 1 2 3 3 3 0 Intermediate filament protein Atg14 PF10186.9 EMG48616.1 - 8.8 5.3 122.5 0.13 11.3 11.7 6.6 1 1 4 5 5 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 SNARE PF05739.19 EMG48617.1 - 9.4e-06 25.5 2.4 2.5e-05 24.2 2.4 1.8 1 0 0 1 1 1 1 SNARE domain Pex24p PF06398.11 EMG48617.1 - 0.21 10.5 4.2 2.2 7.2 0.1 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin PCRF PF03462.18 EMG48617.1 - 0.43 10.4 5.7 0.33 10.8 0.6 2.2 2 0 0 2 2 2 0 PCRF domain POTRA_3 PF17287.2 EMG48617.1 - 1.1 8.8 4.4 0.9 9.1 0.3 2.8 3 0 0 3 3 3 0 POTRA domain Syntaxin_2 PF14523.6 EMG48617.1 - 1.7 9.1 15.2 0.48 10.8 5.3 3.2 2 1 0 2 2 2 0 Syntaxin-like protein PhoU PF01895.19 EMG48617.1 - 2.1 8.8 10.0 4 8.0 0.5 3.2 3 0 0 3 3 3 0 PhoU domain EMP24_GP25L PF01105.24 EMG48617.1 - 3.2 7.6 10.1 8 6.4 9.5 2.2 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4988 PF16378.5 EMG48617.1 - 7.9 6.1 7.6 16 5.1 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function MPM1 PF17234.2 EMG48618.1 - 9.1e-48 162.7 10.1 9.1e-48 162.7 10.1 1.8 2 1 0 2 2 2 1 Mitochondrial peculiar membrane protein 1 HlyC PF02794.16 EMG48618.1 - 0.13 12.2 0.1 0.51 10.2 0.0 2.0 1 1 1 2 2 2 0 RTX toxin acyltransferase family YtxH PF12732.7 EMG48618.1 - 0.35 11.4 2.1 32 5.1 0.1 2.6 2 1 0 2 2 2 0 YtxH-like protein Fib_alpha PF08702.10 EMG48618.1 - 1 9.6 7.0 0.71 10.1 1.6 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family tRNA-synt_1c PF00749.21 EMG48619.1 - 1.6e-101 339.3 0.0 2.5e-101 338.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain SAM_KSR1 PF13543.6 EMG48619.1 - 0.04 14.1 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 SMC_N PF02463.19 EMG48620.1 - 1.8e-17 63.5 30.6 4e-17 62.4 30.6 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EMG48620.1 - 2.2e-13 50.7 10.7 2.2e-13 50.7 10.7 3.9 1 1 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 EMG48620.1 - 6.9e-13 49.5 27.3 6.9e-13 49.5 27.3 6.1 2 2 1 4 4 3 1 AAA domain AAA_29 PF13555.6 EMG48620.1 - 3e-06 26.9 0.2 1e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fib_alpha PF08702.10 EMG48620.1 - 0.0046 17.1 7.2 0.0046 17.1 7.2 5.2 3 2 1 4 4 4 2 Fibrinogen alpha/beta chain family AAA_21 PF13304.6 EMG48620.1 - 0.0048 16.8 0.1 0.0048 16.8 0.1 3.6 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EMG48620.1 - 0.0048 17.1 0.2 0.18 11.9 0.0 3.2 2 0 0 2 2 2 1 AAA domain HupH_C PF04809.13 EMG48620.1 - 0.0089 15.7 0.0 0.11 12.2 0.0 2.7 2 0 0 2 2 2 1 HupH hydrogenase expression protein, C-terminal conserved region NACHT PF05729.12 EMG48620.1 - 0.012 15.5 0.2 0.18 11.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Baculo_PEP_C PF04513.12 EMG48620.1 - 0.012 15.6 0.6 0.012 15.6 0.6 5.7 4 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 EMG48620.1 - 0.014 15.7 0.7 0.014 15.7 0.7 7.9 4 1 2 7 7 7 0 Domain of unknown function (DUF5082) RNA_helicase PF00910.22 EMG48620.1 - 0.075 13.4 6.4 0.14 12.5 0.1 3.6 2 1 1 3 3 3 0 RNA helicase AAA PF00004.29 EMG48620.1 - 0.12 12.8 0.7 0.91 9.9 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MukB PF04310.12 EMG48620.1 - 0.34 10.7 0.0 0.34 10.7 0.0 3.9 4 0 0 4 4 4 0 MukB N-terminal DUF948 PF06103.11 EMG48620.1 - 1.1 9.6 19.7 0.26 11.6 0.7 5.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.6 EMG48620.1 - 1.2 8.8 70.5 1.1 8.9 10.1 6.1 3 2 1 4 4 4 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 EMG48620.1 - 1.3 9.1 40.7 0.22 11.5 5.8 6.6 5 2 3 8 8 7 0 Protein of unknown function (DUF1664) AAA_16 PF13191.6 EMG48620.1 - 1.4 9.3 4.6 3.1 8.1 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 EMG48620.1 - 1.4 8.8 6.6 0.74 9.7 0.1 3.7 3 0 0 3 3 3 0 RsgA GTPase DUF812 PF05667.11 EMG48620.1 - 1.5 7.7 79.7 0.75 8.6 23.3 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF812) AAA_27 PF13514.6 EMG48620.1 - 1.7 8.2 21.1 0.15 11.6 2.4 4.5 3 1 0 3 3 3 0 AAA domain EF-hand_7 PF13499.6 EMG48621.1 - 7.3e-16 58.4 0.2 9.2e-10 38.8 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EMG48621.1 - 4.1e-13 48.1 0.8 0.00013 21.6 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EMG48621.1 - 5.5e-13 47.5 0.1 0.0001 21.6 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EMG48621.1 - 7.5e-13 48.6 0.0 1.1e-07 32.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EMG48621.1 - 1.1e-06 28.4 0.2 9.3e-06 25.4 0.0 2.3 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_11 PF08976.11 EMG48621.1 - 0.0052 17.6 0.0 0.016 16.0 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EMG48621.1 - 0.027 14.0 1.0 2.8 7.6 0.0 2.9 3 0 0 3 3 3 0 EF hand EF-hand_14 PF17959.1 EMG48621.1 - 0.027 14.8 0.0 6.6 7.2 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain L27_2 PF09045.10 EMG48621.1 - 0.03 14.3 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 L27_2 DUF211 PF02680.14 EMG48621.1 - 0.12 12.6 0.3 8.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 LIDHydrolase PF10230.9 EMG48622.1 - 6.4e-54 183.3 0.5 7.3e-54 183.1 0.5 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase TANGO2 PF05742.12 EMG48623.1 - 2.9e-72 243.7 0.0 3.4e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 RNA_pol_Rpb1_3 PF04983.18 EMG48623.1 - 0.11 12.4 0.0 3 7.8 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 3 DUF1752 PF08550.10 EMG48624.1 - 0.0067 16.3 1.8 0.03 14.2 1.8 2.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SDA1 PF05285.12 EMG48624.1 - 1.3 8.4 33.3 0.25 10.7 14.7 2.2 2 0 0 2 2 2 0 SDA1 DnaJ PF00226.31 EMG48625.1 - 3.5e-25 87.9 0.9 1.3e-24 86.1 0.9 2.1 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 EMG48625.1 - 6.6e-10 39.0 4.6 1.8e-09 37.7 4.6 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMG48625.1 - 1.3e-06 28.6 1.3 2.9e-06 27.5 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EMG48625.1 - 0.002 18.4 1.3 0.0073 16.6 1.3 1.9 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Phage_int_SAM_4 PF13495.6 EMG48625.1 - 0.007 16.8 1.1 0.019 15.4 0.4 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain RPT PF13446.6 EMG48625.1 - 0.022 14.7 0.0 0.022 14.7 0.0 2.4 2 0 0 2 2 2 0 A repeated domain in UCH-protein zf-C2H2_4 PF13894.6 EMG48625.1 - 0.13 13.2 0.2 0.3 12.0 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMG48625.1 - 0.14 12.7 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger double domain G-patch PF01585.23 EMG48626.1 - 2e-10 40.4 3.1 4e-10 39.4 3.1 1.6 1 0 0 1 1 1 1 G-patch domain SDA1 PF05285.12 EMG48626.1 - 0.0023 17.5 46.6 0.0068 15.9 29.0 2.4 2 0 0 2 2 2 2 SDA1 Staphostatin_B PF09023.10 EMG48626.1 - 0.13 12.3 1.3 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Staphostatin B THOC7 PF05615.13 EMG48626.1 - 0.39 11.0 20.2 0.22 11.8 12.4 2.8 2 0 0 2 2 2 0 Tho complex subunit 7 Peptidase_C54 PF03416.19 EMG48627.1 - 3e-69 233.5 0.0 5.2e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.13 EMG48628.1 - 1.9e-82 275.5 0.3 2.2e-82 275.3 0.3 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF5387 PF17361.2 EMG48628.1 - 0.11 12.1 2.7 0.092 12.4 0.4 1.9 1 1 0 2 2 2 0 Family of unknown function (DUF5387) POP1 PF06978.11 EMG48629.1 - 3.4e-67 226.4 7.3 5.7e-67 225.7 7.3 1.4 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EMG48629.1 - 1.5e-18 66.9 1.6 4.4e-18 65.4 1.2 2.1 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 EMG48629.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DUF3161 PF11362.8 EMG48629.1 - 0.027 14.4 0.3 0.085 12.8 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) ORF6C PF10552.9 EMG48629.1 - 0.12 12.4 1.0 0.35 11.0 0.2 2.2 2 0 0 2 2 2 0 ORF6C domain MFS_1 PF07690.16 EMG48630.1 - 1.2e-32 113.2 31.3 1.6e-32 112.8 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EMG48630.1 - 1.4 8.7 5.0 0.33 10.7 0.1 2.5 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF308 PF03729.13 EMG48630.1 - 1.5 9.2 24.1 0.14 12.5 3.9 4.4 4 1 0 4 4 4 0 Short repeat of unknown function (DUF308) MFS_1 PF07690.16 EMG48631.1 - 5.6e-28 97.9 14.1 5.6e-28 97.9 14.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EMG48632.1 - 3.2e-44 151.3 0.0 1.3e-42 146.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG48632.1 - 9.9e-23 80.7 0.0 4.7e-22 78.5 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase GATase_5 PF13507.6 EMG48632.1 - 0.0043 16.2 0.1 0.0073 15.4 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MRG PF05712.13 EMG48632.1 - 0.044 13.1 0.6 0.59 9.4 0.2 2.2 2 0 0 2 2 2 0 MRG ADH_zinc_N PF00107.26 EMG48633.1 - 3.2e-10 40.1 0.0 6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG48633.1 - 2.7e-08 33.6 0.1 5.7e-08 32.6 0.1 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EMG48633.1 - 0.0016 18.3 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase zf-CCCH_3 PF15663.5 EMG48635.1 - 5.7e-08 32.9 19.3 1.2e-06 28.7 5.5 3.3 1 1 2 3 3 3 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 EMG48635.1 - 5.2e-06 26.3 33.3 0.0011 18.9 2.0 6.1 5 1 0 5 5 5 3 Zinc finger domain zf-CCCH PF00642.24 EMG48635.1 - 4.4e-05 23.3 30.9 0.00013 21.8 0.8 4.8 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EMG48635.1 - 0.00025 21.4 7.2 0.00043 20.7 1.8 5.0 5 0 0 5 5 5 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EMG48635.1 - 0.00032 21.4 30.6 0.0093 16.7 4.0 5.2 2 1 4 6 6 6 3 Torus domain zf-CCCH_4 PF18044.1 EMG48635.1 - 0.16 11.8 34.7 0.18 11.6 3.3 5.0 4 1 0 4 4 4 0 CCCH-type zinc finger ADH_zinc_N PF00107.26 EMG48636.1 - 1.3e-12 47.8 0.1 3.7e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG48636.1 - 4.5e-07 29.7 0.6 4.4e-06 26.5 0.4 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMG48636.1 - 0.0032 18.5 0.0 0.011 16.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMG48636.1 - 0.048 13.6 0.1 0.15 12.0 0.1 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase tRNA-synt_1 PF00133.22 EMG48637.1 - 6.3e-157 523.4 5.4 8.8e-157 522.9 5.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMG48637.1 - 2e-23 83.0 0.3 4.2e-23 82.0 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EMG48637.1 - 1e-18 67.3 0.3 4.4e-11 42.1 0.0 3.4 2 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EMG48637.1 - 0.00013 21.6 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EMG48637.1 - 0.00038 19.9 0.0 0.026 13.9 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EMG48637.1 - 0.0019 17.2 0.3 0.023 13.6 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) zf-FPG_IleRS PF06827.14 EMG48637.1 - 0.26 11.2 3.5 0.62 10.0 3.5 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Ku PF02735.16 EMG48638.1 - 2.1e-22 79.8 0.1 4.8e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain VWA PF00092.28 EMG48638.1 - 7e-09 36.2 1.4 1.6e-08 35.0 1.4 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EMG48638.1 - 1.9e-07 31.7 0.0 5.1e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_N PF03731.15 EMG48638.1 - 3.2e-06 27.1 2.3 1.7e-05 24.7 2.3 2.1 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain MMR_HSR1 PF01926.23 EMG48639.1 - 1.6e-12 47.5 0.1 3.3e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMG48639.1 - 6.4e-05 22.5 0.1 0.00033 20.2 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.13 EMG48639.1 - 0.0026 16.9 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 EMG48639.1 - 0.0046 16.9 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EMG48639.1 - 0.076 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AIG1 PF04548.16 EMG48639.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family KTI12 PF08433.10 EMG48640.1 - 1.7e-85 286.8 0.1 2.1e-85 286.5 0.1 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EMG48640.1 - 0.00057 20.1 0.1 0.0025 18.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMG48640.1 - 0.026 15.1 0.1 0.07 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMG48640.1 - 0.035 14.5 0.1 0.16 12.4 0.0 2.1 2 1 1 3 3 3 0 RNA helicase AAA_22 PF13401.6 EMG48640.1 - 0.052 13.8 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EMG48640.1 - 0.087 12.7 0.1 0.28 11.1 0.1 1.8 1 1 0 1 1 1 0 Adenylylsulphate kinase Utp11 PF03998.13 EMG48641.1 - 3.5e-65 220.3 32.2 4.3e-65 220.1 32.2 1.1 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 EMG48641.1 - 0.012 15.0 1.1 0.012 15.0 1.1 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 RsfS PF02410.15 EMG48642.1 - 7.1e-15 55.3 0.0 1.7e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Drc1-Sld2 PF11719.8 EMG48643.1 - 4.8e-59 201.1 45.4 5.9e-41 141.5 31.2 3.2 1 1 1 2 2 2 2 DNA replication and checkpoint protein DUF1149 PF06619.11 EMG48643.1 - 0.06 13.6 0.0 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1149) SPT6_acidic PF14632.6 EMG48643.1 - 2.6 8.7 20.6 2.2 8.9 8.2 2.6 1 1 1 2 2 2 0 Acidic N-terminal SPT6 zf-C2HC5 PF06221.13 EMG48644.1 - 8.6e-24 83.3 5.9 1.5e-23 82.5 5.9 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF2292 PF10055.9 EMG48644.1 - 0.2 11.4 1.3 0.35 10.6 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) TackOD1 PF18551.1 EMG48644.1 - 0.32 10.6 6.3 0.12 12.1 3.0 1.9 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 MFS_1 PF07690.16 EMG48646.1 - 1.7e-26 93.0 13.6 1.7e-26 93.0 13.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DcpS_C PF11969.8 EMG48647.1 - 6.3e-23 81.4 4.0 1.3e-22 80.5 4.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 EMG48647.1 - 2.2e-18 66.5 4.0 2.3e-18 66.4 2.2 2.1 2 1 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 EMG48647.1 - 4.2e-17 62.7 0.6 1.2e-16 61.2 0.6 1.8 1 0 0 1 1 1 1 HIT domain zf-H2C2_2 PF13465.6 EMG48647.1 - 0.011 16.1 0.5 0.027 14.9 0.5 1.7 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMG48647.1 - 0.045 14.6 0.9 0.19 12.6 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DDE_Tnp_IS1595 PF12762.7 EMG48647.1 - 0.052 13.6 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 ISXO2-like transposase domain zf-C2H2_jaz PF12171.8 EMG48647.1 - 2.7 8.4 6.1 1.1 9.7 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Pkr1 PF08636.10 EMG48648.1 - 4.6e-30 103.6 10.0 5.8e-30 103.3 10.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 O-antigen_lig PF13425.6 EMG48648.1 - 0.00021 20.2 0.5 0.00023 20.1 0.5 1.0 1 0 0 1 1 1 1 O-antigen ligase like membrane protein DUF3169 PF11368.8 EMG48648.1 - 0.001 18.7 0.2 0.0014 18.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Halogen_Hydrol PF10112.9 EMG48648.1 - 0.022 14.8 0.9 0.023 14.7 0.9 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DGF-1_4 PF11024.8 EMG48648.1 - 0.023 15.5 1.2 0.023 15.5 1.2 1.5 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 TssO PF17561.2 EMG48648.1 - 0.028 14.5 0.6 0.028 14.5 0.6 1.8 1 1 1 2 2 2 0 Type VI secretion system, TssO S_4TM PF18159.1 EMG48648.1 - 0.029 13.7 1.2 0.034 13.5 1.2 1.0 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DUF4834 PF16118.5 EMG48648.1 - 0.19 12.7 4.8 0.37 11.8 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) zf-RING_4 PF14570.6 EMG48649.1 - 7.7e-20 70.4 9.8 1.6e-19 69.4 9.8 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EMG48649.1 - 3e-07 30.1 0.0 2.3e-06 27.3 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.11 EMG48649.1 - 8.3e-05 22.6 2.4 0.00023 21.1 2.4 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.6 EMG48649.1 - 0.00034 20.4 4.7 0.00034 20.4 4.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EMG48649.1 - 0.0053 16.1 2.9 0.0053 16.1 2.9 3.5 3 1 1 4 4 4 1 Rtf2 RING-finger zf-RING_2 PF13639.6 EMG48649.1 - 0.024 15.0 6.3 0.058 13.7 6.3 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 EMG48649.1 - 0.027 14.4 6.9 0.067 13.1 6.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMG48649.1 - 0.034 14.0 4.4 0.091 12.6 4.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Bromo_TP PF07524.13 EMG48651.1 - 1.4e-07 31.4 0.0 2.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 EMG48651.1 - 0.0029 17.7 0.2 0.0029 17.7 0.2 3.1 2 1 0 3 3 3 1 Histone-fold protein Citrate_synt PF00285.21 EMG48653.1 - 1.4e-100 336.9 0.0 1.7e-100 336.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Exo5 PF09810.9 EMG48654.1 - 1.7e-40 139.7 0.4 1.2e-39 136.9 0.4 2.0 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EMG48654.1 - 9.7e-05 22.4 0.1 0.022 14.7 0.1 2.5 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily LRR_8 PF13855.6 EMG48655.1 - 7.2e-11 41.7 11.7 1.5e-09 37.4 1.3 5.7 5 1 0 5 5 5 1 Leucine rich repeat FNIP PF05725.12 EMG48655.1 - 9.4e-09 35.3 0.7 4.5 7.5 0.1 8.4 8 4 0 8 8 8 2 FNIP Repeat LRR_4 PF12799.7 EMG48655.1 - 2.2e-08 34.3 29.4 0.011 16.1 1.6 8.8 7 1 2 10 10 10 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMG48655.1 - 0.00042 20.1 1.8 12 6.3 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 EMG48655.1 - 0.069 13.7 12.6 4.5 8.2 0.9 6.3 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_9 PF14580.6 EMG48655.1 - 1.6 8.2 4.0 1.2 8.6 0.2 2.7 3 1 1 4 4 4 0 Leucine-rich repeat GRDP-like PF07173.12 EMG48656.1 - 2.4e-20 73.6 2.5 1.5e-19 71.1 0.1 2.6 2 1 0 2 2 2 1 Glycine-rich domain-containing protein-like VPS28 PF03997.12 EMG48656.1 - 0.00034 20.4 0.1 0.6 9.8 0.0 2.9 3 0 0 3 3 3 2 VPS28 protein GRDP-like PF07173.12 EMG48657.1 - 1.7e-17 64.4 2.4 1e-15 58.6 0.8 2.6 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like SMC_N PF02463.19 EMG48658.1 - 7.8e-54 182.4 43.9 2.1e-33 115.6 1.4 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EMG48658.1 - 1.6e-24 86.5 0.2 1.4e-23 83.4 0.0 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EMG48658.1 - 2.1e-13 51.2 5.6 2.1e-13 51.2 5.6 7.2 3 2 3 6 6 6 2 AAA domain AAA_21 PF13304.6 EMG48658.1 - 1.4e-10 41.5 17.4 1.1e-05 25.4 0.6 4.8 3 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMG48658.1 - 1.2e-07 31.3 0.4 3.3e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EMG48658.1 - 8.4e-06 25.7 35.3 8.4e-06 25.7 35.3 4.3 2 2 2 4 4 4 1 AAA ATPase domain AAA_27 PF13514.6 EMG48658.1 - 0.041 13.5 0.1 0.041 13.5 0.1 5.2 6 1 0 6 6 6 0 AAA domain SbcCD_C PF13558.6 EMG48658.1 - 0.054 13.7 0.0 0.52 10.6 0.0 2.7 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF2939 PF11159.8 EMG48658.1 - 0.11 12.9 0.1 23 5.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) DSPc PF00782.20 EMG48659.1 - 3.1e-27 95.0 0.1 1.9e-26 92.5 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMG48659.1 - 0.0015 18.2 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EMG48659.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain Zn_ribbon_SprT PF17283.2 EMG48659.1 - 0.017 15.0 0.3 0.017 15.0 0.3 2.9 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DUF674 PF05056.12 EMG48659.1 - 0.03 13.2 0.4 0.079 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF674) RNHCP PF12647.7 EMG48659.1 - 0.042 13.8 1.1 1 9.4 0.1 2.6 2 0 0 2 2 2 0 RNHCP domain HypA PF01155.19 EMG48659.1 - 0.074 13.1 0.6 0.99 9.5 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PHD PF00628.29 EMG48659.1 - 0.087 12.7 2.2 6.7 6.7 0.2 2.6 2 0 0 2 2 2 0 PHD-finger HU-CCDC81_bac_2 PF18175.1 EMG48659.1 - 0.17 11.7 0.2 0.54 10.2 0.1 1.8 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 CTU2 PF10288.9 EMG48660.1 - 2.8e-19 69.4 0.1 8.7e-19 67.8 0.1 1.9 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 Apc15p PF05841.11 EMG48660.1 - 3.7e-13 50.4 1.0 1e-12 48.9 1.0 1.8 1 0 0 1 1 1 1 Apc15p protein ATP_bind_3 PF01171.20 EMG48660.1 - 1.7e-05 24.6 0.0 0.23 11.2 0.0 2.4 1 1 0 2 2 2 2 PP-loop family Lar_restr_allev PF14354.6 EMG48660.1 - 0.47 10.9 2.5 3.4 8.1 0.7 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar Mitofilin PF09731.9 EMG48661.1 - 2.1e-58 198.6 27.3 5.6e-51 174.2 22.3 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Peptidase_C11 PF03415.14 EMG48661.1 - 0.05 13.0 5.4 0.26 10.7 5.4 1.9 1 1 0 1 1 1 0 Clostripain family DUF4817 PF16087.5 EMG48661.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) XhlA PF10779.9 EMG48661.1 - 3.7 7.8 10.1 0.22 11.7 0.5 3.6 3 1 0 3 3 3 0 Haemolysin XhlA MRP-S27 PF10037.9 EMG48661.1 - 5.2 5.8 18.1 0.032 13.1 5.5 2.4 1 1 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 WD40 PF00400.32 EMG48662.1 - 9.8e-26 89.5 16.0 0.00026 21.7 0.1 9.7 9 1 1 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG48662.1 - 2.7e-12 46.8 0.0 0.0065 16.7 0.0 5.7 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EMG48662.1 - 3.5e-07 29.8 0.1 2.5e-06 27.0 0.2 2.3 3 1 0 3 3 3 1 WD40-like domain eIF2A PF08662.11 EMG48662.1 - 2.3e-05 24.4 0.1 0.14 12.0 0.0 4.0 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.9 EMG48662.1 - 0.02 14.2 0.1 0.11 11.7 0.0 2.3 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Nup160 PF11715.8 EMG48662.1 - 0.052 12.2 0.1 0.2 10.2 0.1 2.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF3425 PF11905.8 EMG48663.1 - 0.1 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) Cyt-b5 PF00173.28 EMG48664.1 - 4.6e-14 52.3 0.0 5.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acetyltransf_1 PF00583.25 EMG48665.1 - 1e-13 51.5 0.0 1.3e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMG48665.1 - 5.7e-11 42.5 0.0 5.8e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMG48665.1 - 1.4e-10 41.4 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EMG48665.1 - 2.3e-05 24.0 2.6 2.9e-05 23.7 2.6 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 EMG48665.1 - 3.5e-05 24.0 0.7 0.00011 22.4 0.4 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMG48665.1 - 8.4e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EMG48665.1 - 0.15 12.7 0.0 0.21 12.2 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaJ PF00226.31 EMG48666.1 - 1.5e-15 57.1 1.6 1.5e-15 57.1 1.6 2.3 2 0 0 2 2 2 1 DnaJ domain Sec63 PF02889.16 EMG48666.1 - 0.0096 15.1 0.0 0.019 14.1 0.0 1.5 1 1 0 1 1 1 1 Sec63 Brl domain AICARFT_IMPCHas PF01808.18 EMG48667.1 - 5.4e-92 308.4 0.0 7.4e-92 307.9 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EMG48667.1 - 1.7e-24 85.8 0.0 4.8e-24 84.4 0.0 1.8 1 0 0 1 1 1 1 MGS-like domain Ribosomal_L15e PF00827.17 EMG48668.1 - 1.5e-89 298.8 11.8 1.9e-89 298.5 11.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 AAA PF00004.29 EMG48669.1 - 1.2e-42 145.5 0.0 2e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMG48669.1 - 2.4e-09 36.8 0.1 4.8e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EMG48669.1 - 5.2e-09 35.9 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EMG48669.1 - 2.5e-07 31.2 0.7 0.00014 22.3 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EMG48669.1 - 1.3e-06 28.4 0.1 2e-05 24.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMG48669.1 - 3.3e-06 27.3 0.0 6.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EMG48669.1 - 5.8e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EMG48669.1 - 5.8e-05 23.1 0.0 9.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EMG48669.1 - 0.00068 19.9 0.2 0.029 14.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EMG48669.1 - 0.0028 18.2 0.2 0.013 16.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 EMG48669.1 - 0.0029 16.9 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 EMG48669.1 - 0.003 17.9 0.0 0.007 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 EMG48669.1 - 0.0056 16.1 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EMG48669.1 - 0.0067 16.6 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMG48669.1 - 0.0096 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 EMG48669.1 - 0.016 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EMG48669.1 - 0.022 14.1 0.7 0.12 11.7 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_14 PF13173.6 EMG48669.1 - 0.026 14.6 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMG48669.1 - 0.027 14.7 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMG48669.1 - 0.03 13.8 0.0 0.074 12.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EMG48669.1 - 0.051 13.1 0.1 0.2 11.2 0.1 2.0 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EMG48669.1 - 0.062 12.7 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF4200 PF13863.6 EMG48669.1 - 0.063 13.7 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Parvo_NS1 PF01057.17 EMG48669.1 - 0.087 11.9 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 EMG48669.1 - 0.096 12.5 1.4 0.93 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EMG48669.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EMG48669.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EMG48669.1 - 0.12 12.0 0.1 0.41 10.3 0.1 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain KOW PF00467.29 EMG48670.1 - 0.0005 19.9 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 KOW motif DUF3912 PF13051.6 EMG48670.1 - 0.16 12.3 1.8 0.31 11.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) Vasculin PF15337.6 EMG48670.1 - 0.27 12.1 1.8 0.63 10.9 0.7 2.2 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 EF-hand_7 PF13499.6 EMG48671.1 - 7.2e-22 77.6 10.4 6e-11 42.6 1.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EMG48671.1 - 8.8e-20 68.7 13.0 6e-08 31.7 0.1 4.9 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EMG48671.1 - 1.2e-16 59.1 9.0 2.8e-07 29.9 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EMG48671.1 - 3.9e-15 55.4 12.3 6.4e-09 35.5 1.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EMG48671.1 - 1.1e-10 40.5 1.9 0.00017 20.9 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 EMG48671.1 - 5.9e-06 26.2 3.7 0.00015 21.7 0.1 2.7 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EMG48671.1 - 0.00026 21.3 0.5 0.015 15.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain H-kinase_dim PF02895.14 EMG48671.1 - 0.0096 16.3 0.2 0.024 15.0 0.0 1.7 2 0 0 2 2 2 1 Signal transducing histidine kinase, homodimeric domain FIVAR PF07554.13 EMG48671.1 - 0.017 15.8 0.5 0.047 14.5 0.5 1.7 1 0 0 1 1 1 0 FIVAR domain PhetRS_B1 PF18262.1 EMG48671.1 - 0.089 13.0 2.1 0.18 12.0 0.7 2.0 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Caleosin PF05042.13 EMG48671.1 - 0.13 12.2 0.7 0.75 9.7 0.1 2.3 1 1 2 3 3 3 0 Caleosin related protein SUB1_ProdP9 PF18213.1 EMG48671.1 - 0.32 10.9 2.2 0.81 9.6 0.2 2.3 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 CAP_GLY PF01302.25 EMG48672.1 - 7.7e-20 70.7 0.5 1.3e-19 70.0 0.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain MbeD_MobD PF04899.12 EMG48672.1 - 0.069 13.3 8.0 0.24 11.5 0.2 4.3 3 1 0 3 3 3 0 MbeD/MobD like Cas6 PF09559.10 EMG48672.1 - 2.6 7.9 7.0 3.1 7.7 4.2 2.6 2 1 0 2 2 2 0 Cas6 Crispr HrpB7 PF09486.10 EMG48672.1 - 5.4 7.4 11.1 0.27 11.6 4.2 2.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) PIGA PF08288.12 EMG48673.1 - 1.3e-44 150.7 0.5 3.5e-44 149.3 0.5 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 EMG48673.1 - 6.2e-32 110.5 0.0 8.8e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMG48673.1 - 4.4e-28 98.4 0.2 6.4e-28 97.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EMG48673.1 - 2.1e-23 83.2 0.1 3.8e-23 82.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EMG48673.1 - 1.7e-09 38.3 0.0 3e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EMG48673.1 - 0.00037 20.5 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EMG48673.1 - 0.0028 18.0 0.0 0.0054 17.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 MFS_1 PF07690.16 EMG48674.1 - 3.6e-49 167.6 24.1 7.9e-41 140.2 16.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2569 PF10754.9 EMG48674.1 - 0.013 15.9 0.1 0.013 15.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) Holin_BhlA PF10960.8 EMG48674.1 - 0.13 12.2 0.4 0.88 9.6 0.0 2.4 2 0 0 2 2 2 0 BhlA holin family DUF5455 PF17537.2 EMG48674.1 - 1.2 9.6 6.4 0.22 11.9 0.6 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5455) RRM_9 PF18444.1 EMG48675.1 - 3e-25 87.9 0.1 6.6e-25 86.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif LRR_4 PF12799.7 EMG48675.1 - 0.00025 21.4 14.0 0.0003 21.1 3.5 3.7 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG48675.1 - 0.0055 16.4 7.7 0.01 15.5 4.8 2.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 EMG48675.1 - 0.016 14.7 2.3 0.036 13.6 2.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeat SP24 PF16504.5 EMG48675.1 - 0.09 12.8 0.1 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative virion membrane protein of plant and insect virus MCM PF00493.23 EMG48677.1 - 1.3e-98 328.6 0.0 2.3e-98 327.8 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM2_N PF12619.8 EMG48677.1 - 2.1e-46 158.0 37.1 2.1e-46 158.0 37.1 4.0 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_OB PF17207.3 EMG48677.1 - 3.9e-38 130.2 0.1 8.1e-38 129.1 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EMG48677.1 - 2.9e-26 91.7 0.5 7.4e-26 90.4 0.5 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMG48677.1 - 1.6e-10 41.5 0.1 1.6e-10 41.5 0.1 2.6 4 0 0 4 4 4 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMG48677.1 - 4e-08 32.9 0.0 5.9e-06 25.8 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMG48677.1 - 7.3e-08 32.5 1.2 5.4e-06 26.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EMG48677.1 - 0.0014 18.5 0.0 0.026 14.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMG48677.1 - 0.0032 17.2 0.1 0.019 14.7 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EMG48677.1 - 0.82 10.0 4.6 2 8.8 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain Longin PF13774.6 EMG48678.1 - 1.9e-24 85.5 0.2 3.2e-24 84.8 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EMG48678.1 - 3.1e-15 55.7 0.2 5.7e-15 54.9 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.12 EMG48678.1 - 0.11 12.6 0.5 0.16 12.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4588 PF15251.6 EMG48679.1 - 4.3e-28 98.8 13.6 1.8e-24 86.9 2.9 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4588) Nre_N PF04894.12 EMG48679.1 - 0.0089 15.9 2.4 0.041 13.7 0.2 2.1 2 1 0 2 2 2 1 Archaeal Nre, N-terminal Hexapep PF00132.24 EMG48680.1 - 4e-10 39.0 7.4 3.9e-06 26.4 1.2 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EMG48680.1 - 2.6e-05 24.7 0.0 4.5e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EMG48680.1 - 8.1e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.19 EMG48680.1 - 0.00039 20.4 0.2 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 Cytidylyltransferase SUIM_assoc PF16619.5 EMG48680.1 - 0.0012 18.9 0.5 0.0012 18.9 0.5 1.9 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF4954 PF16314.5 EMG48680.1 - 0.004 15.4 0.9 0.0078 14.4 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EMG48680.1 - 0.0058 15.6 4.7 0.036 13.0 4.7 2.1 1 1 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 EMG48680.1 - 0.62 9.9 9.9 20 5.0 1.6 3.5 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase TPR_12 PF13424.6 EMG48681.1 - 4.7e-06 26.8 6.8 0.029 14.6 1.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMG48681.1 - 0.039 14.6 0.3 0.42 11.3 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMG48681.1 - 0.08 13.1 9.3 2.3 8.5 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMG48681.1 - 0.12 12.2 9.9 1.6 8.7 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5516 PF17637.2 EMG48681.1 - 0.33 10.7 2.0 5.2 6.9 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5516) TPR_14 PF13428.6 EMG48681.1 - 0.93 10.5 2.7 22 6.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.24 EMG48682.1 - 2e-85 287.3 13.1 2.4e-85 287.1 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG48682.1 - 1.1e-25 90.3 28.7 1.8e-17 63.3 1.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TB2_DP1_HVA22 PF03134.19 EMG48682.1 - 0.28 11.1 6.2 0.064 13.2 1.8 2.2 2 0 0 2 2 2 0 TB2/DP1, HVA22 family Brr6_like_C_C PF10104.9 EMG48683.1 - 1.8e-38 131.3 6.3 3.4e-38 130.4 6.3 1.5 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Chordopox_G3 PF06129.12 EMG48683.1 - 2.1 9.1 6.2 12 6.6 0.1 3.0 3 0 0 3 3 3 0 Chordopoxvirus G3 protein MFS_1 PF07690.16 EMG48684.1 - 3.7e-28 98.5 38.7 3.7e-28 98.5 38.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TFIID_20kDa PF03847.13 EMG48685.1 - 2.2e-17 63.3 0.0 4.6e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Pkinase PF00069.25 EMG48686.1 - 3e-60 203.8 0.0 5.4e-60 203.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG48686.1 - 2.8e-35 121.9 0.0 4.3e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG48686.1 - 6.9e-05 21.8 0.0 6.9e-05 21.8 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EMG48686.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family SOAR PF16533.5 EMG48686.1 - 0.38 10.8 2.0 0.33 11.0 0.2 1.8 2 0 0 2 2 2 0 STIM1 Orai1-activating region zinc_ribbon_2 PF13240.6 EMG48687.1 - 0.001 18.7 0.9 0.001 18.7 0.9 4.6 7 0 0 7 7 7 1 zinc-ribbon domain zinc-ribbons_6 PF07191.12 EMG48687.1 - 0.9 9.6 26.2 1.4 8.9 10.2 3.9 3 1 0 3 3 3 0 zinc-ribbons C1_1 PF00130.22 EMG48687.1 - 3.5 7.6 21.8 0.55 10.2 1.3 5.0 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_2 PF07719.17 EMG48689.1 - 0.0011 18.9 1.4 7.2 7.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMG48689.1 - 0.0031 18.2 0.0 8.2 7.5 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMG48689.1 - 0.0036 17.8 0.1 0.1 13.1 0.1 3.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMG48689.1 - 0.019 15.1 2.1 9.1 6.8 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EMG48689.1 - 0.18 10.9 4.6 0.76 8.8 2.9 2.9 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference Methyltransf_16 PF10294.9 EMG48690.1 - 4.2e-12 46.1 0.0 7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 EMG48690.1 - 0.0024 18.5 0.1 0.017 15.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMG48690.1 - 0.0045 16.9 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG48690.1 - 0.035 14.9 0.0 0.066 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EMG48690.1 - 0.044 13.1 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_25 PF13649.6 EMG48690.1 - 0.11 13.3 0.0 0.44 11.3 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EMG48690.1 - 0.2 11.4 0.0 0.44 10.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF202 PF02656.15 EMG48691.1 - 1.6e-24 86.1 3.2 1.8e-24 86.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5373 PF17343.2 EMG48691.1 - 0.041 13.7 2.1 0.067 13.0 2.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5373) DUF3185 PF11381.8 EMG48691.1 - 0.052 13.6 0.0 0.052 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) SdpI PF13630.6 EMG48691.1 - 0.62 10.2 5.6 0.24 11.6 2.8 1.7 2 0 0 2 2 2 0 SdpI/YhfL protein family Tetraspanin PF00335.20 EMG48691.1 - 5 6.8 5.9 1.5 8.5 3.0 1.5 2 0 0 2 2 2 0 Tetraspanin family KRE1 PF17056.5 EMG48692.1 - 6.6e-27 93.0 9.6 1.3e-26 92.1 9.6 1.5 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 Metallophos PF00149.28 EMG48693.1 - 3.1e-39 135.6 0.3 4.1e-39 135.2 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mon1 PF03164.14 EMG48694.1 - 6.7e-113 377.8 17.2 8.1e-113 377.5 17.2 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 RRF PF01765.19 EMG48695.1 - 1.1e-34 119.8 1.5 1.1e-34 119.8 1.5 1.7 2 0 0 2 2 2 1 Ribosome recycling factor Rubrerythrin PF02915.17 EMG48695.1 - 0.021 15.2 1.3 0.046 14.1 1.3 1.6 1 0 0 1 1 1 0 Rubrerythrin CbiA PF01656.23 EMG48695.1 - 0.025 14.6 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1382 PF07131.11 EMG48695.1 - 0.08 13.0 0.4 18 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1382) DAGAT PF03982.13 EMG48695.1 - 0.16 10.9 1.3 2.2 7.1 0.3 2.2 2 0 0 2 2 2 0 Diacylglycerol acyltransferase CHIP_TPR_N PF18391.1 EMG48695.1 - 7.3 7.4 7.1 6.2 7.7 4.0 2.3 2 1 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Ipi1_N PF12333.8 EMG48696.1 - 6.7e-23 81.2 2.3 6.7e-23 81.2 2.3 2.3 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation CAS_CSE1 PF03378.15 EMG48696.1 - 0.014 13.9 0.8 0.021 13.3 0.8 1.3 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Glyco_hydro_49 PF03718.13 EMG48696.1 - 0.38 10.8 5.2 3.4 7.7 0.2 2.7 3 0 0 3 3 3 0 Glycosyl hydrolase family 49 TAL_FSA PF00923.19 EMG48697.1 - 1.8e-97 326.1 1.5 2.1e-97 325.9 1.5 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF3887 PF13026.6 EMG48697.1 - 0.93 10.4 5.6 2.4 9.1 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3887) Flavokinase PF01687.17 EMG48698.1 - 1.5e-32 112.2 0.0 1.8e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Peptidase_M24_C PF16188.5 EMG48700.1 - 3e-19 68.8 0.0 4.2e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Peptidase_M24 PF00557.24 EMG48700.1 - 3.3e-19 69.4 0.0 4.1e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1769 PF08588.10 EMG48702.1 - 1.7e-20 72.9 0.4 3.8e-20 71.8 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Clat_adaptor_s PF01217.20 EMG48703.1 - 4e-16 59.2 3.0 1.1e-15 57.8 3.0 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 EMG48703.1 - 0.061 13.3 0.8 0.13 12.3 0.2 1.7 1 1 1 2 2 2 0 AP-5 complex subunit sigma-1 VTC PF09359.10 EMG48704.1 - 1.8e-56 191.6 7.3 4e-56 190.4 7.3 1.6 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 EMG48704.1 - 7.3e-10 39.1 3.6 9.8e-10 38.7 2.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EMG48704.1 - 0.00057 19.9 6.4 0.0088 16.0 1.0 4.7 2 2 2 4 4 4 3 SPX domain Peptidase_U4 PF03419.13 EMG48704.1 - 0.12 11.7 0.7 0.2 10.9 0.7 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Inhibitor_I53 PF11714.8 EMG48704.1 - 8 6.7 7.9 2.8 8.2 1.1 2.4 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Peptidase_C48 PF02902.19 EMG48705.1 - 1.3e-30 106.8 0.4 2.1e-30 106.2 0.1 1.5 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain RNA12 PF10443.9 EMG48706.1 - 4.5e-152 506.8 1.5 3.8e-97 325.8 0.1 2.6 2 1 1 3 3 3 2 RNA12 protein RRM_1 PF00076.22 EMG48706.1 - 0.0014 18.4 0.0 0.0075 16.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YIF1 PF03878.15 EMG48706.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 YIF1 AAA PF00004.29 EMG48707.1 - 2.1e-38 131.7 0.0 6.9e-38 130.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMG48707.1 - 2.1e-11 43.4 0.0 5.1e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EMG48707.1 - 1.7e-06 28.5 0.2 0.00045 20.6 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 EMG48707.1 - 1.9e-06 28.0 0.0 4.5e-05 23.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EMG48707.1 - 2.7e-06 27.2 0.0 1.5e-05 24.8 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EMG48707.1 - 6.9e-05 23.0 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EMG48707.1 - 0.00015 21.8 0.1 0.004 17.2 0.1 2.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMG48707.1 - 0.00043 20.6 0.5 0.042 14.1 0.0 2.8 1 1 2 3 3 3 1 AAA domain AAA_33 PF13671.6 EMG48707.1 - 0.00058 20.0 0.0 0.00094 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EMG48707.1 - 0.00074 19.0 0.1 0.72 9.2 0.0 2.6 2 1 0 3 3 3 2 Bacterial TniB protein IstB_IS21 PF01695.17 EMG48707.1 - 0.0011 18.7 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EMG48707.1 - 0.0013 18.2 0.1 0.0029 17.0 0.0 1.5 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EMG48707.1 - 0.0013 19.1 0.0 0.0031 17.9 0.0 1.9 1 1 0 1 1 1 1 RNA helicase Bac_DnaA PF00308.18 EMG48707.1 - 0.0015 18.4 0.0 0.0054 16.6 0.0 1.9 2 1 0 2 2 1 1 Bacterial dnaA protein AAA_18 PF13238.6 EMG48707.1 - 0.002 18.7 0.0 0.0046 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EMG48707.1 - 0.0025 17.4 0.1 0.011 15.3 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EMG48707.1 - 0.0032 16.6 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.13 EMG48707.1 - 0.0046 16.2 0.0 0.0089 15.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 EMG48707.1 - 0.0054 16.5 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EMG48707.1 - 0.0068 16.3 0.1 0.033 14.1 0.1 2.0 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.13 EMG48707.1 - 0.0084 15.3 0.0 0.015 14.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 EMG48707.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Hydin_ADK PF17213.3 EMG48707.1 - 0.012 15.9 0.0 2.9 8.1 0.0 2.6 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain ATPase_2 PF01637.18 EMG48707.1 - 0.014 15.4 1.9 0.12 12.2 0.0 2.8 1 1 2 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 EMG48707.1 - 0.022 14.4 0.0 0.084 12.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 EMG48707.1 - 0.025 14.5 0.1 0.079 12.9 0.0 1.8 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 EMG48707.1 - 0.028 14.0 0.1 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EMG48707.1 - 0.032 14.7 0.0 0.079 13.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 EMG48707.1 - 0.036 13.2 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 EMG48707.1 - 0.038 14.4 0.0 0.087 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EMG48707.1 - 0.067 12.9 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EMG48707.1 - 0.079 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 EMG48707.1 - 0.094 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EMG48707.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EMG48707.1 - 0.12 11.8 0.3 6.2 6.2 0.1 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain Sugar_tr PF00083.24 EMG48708.1 - 1.6e-79 267.9 23.6 2.2e-79 267.4 23.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG48708.1 - 3.2e-27 95.4 29.9 3.2e-27 95.4 29.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EMG48708.1 - 0.014 13.7 0.3 0.014 13.7 0.3 2.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family tRNA_U5-meth_tr PF05958.11 EMG48709.1 - 4.8e-21 75.1 0.6 2.3e-20 72.9 0.3 2.0 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.16 EMG48709.1 - 3.8e-08 33.3 0.1 7.9e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 EMG48709.1 - 1e-06 28.7 0.5 6.7e-06 26.0 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain TRAM PF01938.20 EMG48709.1 - 1.2e-06 28.4 0.2 6.6e-06 26.0 0.1 2.3 2 0 0 2 2 2 1 TRAM domain Methyltransf_25 PF13649.6 EMG48709.1 - 1.2e-05 26.0 0.0 8.7e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EMG48709.1 - 6.5e-05 22.5 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EMG48709.1 - 0.00095 18.6 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EMG48709.1 - 0.0037 16.6 0.2 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EMG48709.1 - 0.0052 16.3 0.1 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 EMG48709.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EMG48709.1 - 0.032 14.9 0.0 0.13 13.0 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 EMG48709.1 - 0.033 13.4 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase MA3 PF02847.17 EMG48710.1 - 4.8e-25 87.7 0.1 1e-23 83.5 0.0 3.0 2 1 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EMG48710.1 - 2.8e-20 72.9 10.5 2.6e-18 66.4 7.4 2.8 2 1 0 2 2 2 2 MIF4G domain CAP_N PF01213.19 EMG48711.1 - 1.8e-113 379.2 5.2 1.8e-113 379.2 5.2 1.6 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EMG48711.1 - 1.7e-54 183.7 3.3 2.5e-54 183.2 3.3 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PRIMA1 PF16101.5 EMG48711.1 - 0.023 14.8 13.9 0.14 12.2 4.7 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Actin PF00022.19 EMG48712.1 - 5.3e-50 170.2 0.0 3.8e-30 104.8 0.0 2.6 2 1 0 2 2 2 2 Actin Methyltr_RsmB-F PF01189.17 EMG48713.1 - 1.2e-80 269.9 0.0 2.4e-80 268.9 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EMG48713.1 - 1.9e-08 34.7 0.0 5.8e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EMG48713.1 - 0.026 14.6 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Gcd10p PF04189.13 EMG48714.1 - 9.2e-96 320.5 1.3 1.2e-95 320.1 1.3 1.1 1 0 0 1 1 1 1 Gcd10p family Methyltransf_12 PF08242.12 EMG48714.1 - 0.047 14.4 0.0 0.83 10.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain S4 PF01479.25 EMG48715.1 - 8.1e-14 51.1 0.1 2.9e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 S4 domain MTS PF05175.14 EMG48715.1 - 2.7e-08 33.6 0.0 7.2e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EMG48715.1 - 5.9e-08 32.7 0.3 2.3e-07 30.8 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 EMG48715.1 - 9e-06 25.3 1.5 1.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EMG48715.1 - 1.1e-05 26.1 0.0 4.7e-05 24.0 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 EMG48715.1 - 6.7e-05 22.4 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 RNA methyltransferase Cons_hypoth95 PF03602.15 EMG48715.1 - 0.0011 18.7 0.2 0.0059 16.3 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 AviRa PF11599.8 EMG48715.1 - 0.0024 17.4 0.1 0.0024 17.4 0.1 2.5 2 1 1 3 3 3 1 RRNA methyltransferase AviRa Methyltransf_18 PF12847.7 EMG48715.1 - 0.003 17.5 0.1 0.02 14.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG48715.1 - 0.0031 18.2 0.1 0.028 15.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ResB PF05140.14 EMG48715.1 - 0.014 14.2 1.3 0.025 13.3 1.3 1.3 1 0 0 1 1 1 0 ResB-like family Methyltransf_23 PF13489.6 EMG48715.1 - 0.015 15.2 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EMG48715.1 - 0.11 13.2 0.0 0.42 11.3 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain UPF0020 PF01170.18 EMG48715.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MutS_V PF00488.21 EMG48716.1 - 1.1e-67 227.7 0.0 3e-67 226.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMG48716.1 - 2.5e-29 102.9 10.3 2.5e-29 102.9 10.3 4.3 3 2 0 3 3 3 1 MutS domain III MutS_I PF01624.20 EMG48716.1 - 1.1e-19 70.7 0.0 7.2e-19 68.1 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 EMG48716.1 - 7.5e-11 42.5 0.0 7.5e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 MutS domain II Eaf7 PF07904.13 EMG48716.1 - 0.0002 21.7 41.3 0.3 11.5 41.3 4.3 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Gar1 PF04410.14 EMG48717.1 - 2.4e-48 163.8 4.4 2.4e-48 163.8 4.4 2.8 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region DUF5072 PF16807.5 EMG48717.1 - 0.026 14.6 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) CDC45 PF02724.14 EMG48717.1 - 0.3 9.3 25.8 0.0068 14.8 2.2 2.1 2 0 0 2 2 2 0 CDC45-like protein SR-25 PF10500.9 EMG48717.1 - 1 8.9 17.8 0.73 9.4 5.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SDA1 PF05285.12 EMG48717.1 - 5.9 6.2 32.4 5.9 6.2 4.4 2.2 2 0 0 2 2 2 0 SDA1 Snapin_Pallidin PF14712.6 EMG48718.1 - 0.014 15.8 0.4 0.029 14.8 0.4 1.5 1 0 0 1 1 1 0 Snapin/Pallidin Tox-MPTase2 PF15638.6 EMG48718.1 - 0.058 13.1 0.1 0.076 12.8 0.1 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 MFS_1 PF07690.16 EMG48719.1 - 1.2e-37 129.7 29.9 1.2e-37 129.7 29.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG48719.1 - 7.4e-07 28.4 35.1 2e-06 26.9 11.6 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter RseC_MucC PF04246.12 EMG48719.1 - 1.1 9.2 8.9 0.62 10.0 2.8 3.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Deltameth_res PF16020.5 EMG48719.1 - 4.6 7.2 10.4 2.7 7.9 0.0 4.2 4 0 0 4 4 4 0 Deltamethrin resistance E1-E2_ATPase PF00122.20 EMG48719.1 - 8.7 5.8 9.2 0.34 10.4 1.4 2.5 2 1 0 2 2 2 0 E1-E2 ATPase DnaJ_C PF01556.18 EMG48720.1 - 5.3e-41 140.2 0.2 9.4e-41 139.3 0.2 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMG48720.1 - 1.5e-26 92.3 3.1 2.8e-26 91.4 3.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EMG48720.1 - 1.3e-14 54.3 20.7 2.3e-14 53.5 20.7 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF4416 PF14385.6 EMG48720.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) Anti-TRAP PF15777.5 EMG48720.1 - 0.072 13.1 18.0 0.38 10.7 4.0 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein CxC3 PF18804.1 EMG48720.1 - 0.14 12.1 1.0 0.27 11.1 1.0 1.4 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Malate_DH PF12434.8 EMG48720.1 - 0.24 11.4 2.9 0.21 11.6 0.8 2.0 2 0 0 2 2 2 0 Malate dehydrogenase enzyme HypA PF01155.19 EMG48720.1 - 0.33 11.0 13.6 0.21 11.6 0.9 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NDT80_PhoG PF05224.12 EMG48721.1 - 8.3e-41 140.2 0.3 1.6e-40 139.3 0.3 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family GNAT_acetyltr_2 PF13718.6 EMG48722.1 - 6.8e-99 329.9 0.1 2e-98 328.3 0.0 1.9 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EMG48722.1 - 1.2e-93 313.2 9.5 2.4e-93 312.2 9.5 1.6 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EMG48722.1 - 3.1e-66 222.6 0.0 2.7e-65 219.5 0.0 2.5 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.11 EMG48722.1 - 2e-34 117.4 0.8 5.3e-34 116.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 EMG48722.1 - 0.0021 18.4 0.0 0.29 11.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EMG48722.1 - 0.0034 17.1 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma70_r4_2 PF08281.12 EMG48722.1 - 0.025 14.2 0.5 0.38 10.4 0.0 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 Acetyltransf_7 PF13508.7 EMG48722.1 - 0.059 13.8 0.0 0.43 11.0 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PRK PF00485.18 EMG48723.1 - 9.7e-08 32.0 0.0 2.1e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EMG48723.1 - 1.1e-05 25.9 0.1 3.7e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EMG48723.1 - 0.003 17.3 0.1 0.0051 16.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 EMG48723.1 - 0.0049 16.1 0.6 0.0087 15.3 0.6 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Zeta_toxin PF06414.12 EMG48723.1 - 0.0096 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.12 EMG48723.1 - 0.017 14.9 0.0 0.041 13.7 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EMG48723.1 - 0.021 15.0 0.0 0.06 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EMG48723.1 - 0.029 14.1 0.2 0.065 13.0 0.2 1.8 1 1 0 1 1 1 0 Cytidylate kinase AAA_17 PF13207.6 EMG48723.1 - 0.036 14.5 0.5 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EMG48723.1 - 0.086 12.9 0.2 0.75 9.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 EMG48723.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain CBFD_NFYB_HMF PF00808.23 EMG48724.1 - 1.1e-27 96.0 0.2 1.4e-27 95.7 0.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMG48724.1 - 1.2e-05 25.6 0.1 1.7e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EMG48724.1 - 0.0096 16.0 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EMG48724.1 - 0.038 14.5 1.4 0.22 12.1 0.1 2.4 2 1 1 3 3 3 0 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.13 EMG48724.1 - 0.039 14.0 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-18kDa PF02269.16 EMG48724.1 - 0.042 13.9 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Rft-1 PF04506.13 EMG48725.1 - 1.7e-168 561.5 42.5 2e-168 561.3 42.5 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 EMG48725.1 - 1.2e-06 28.2 21.5 1.2e-06 28.2 21.5 3.4 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 EMG48725.1 - 0.0075 16.3 16.9 0.0075 16.3 16.9 3.5 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain zf-C2H2_10 PF16588.5 EMG48726.1 - 1.6e-12 46.9 6.6 3.1e-12 46.0 6.6 1.5 1 0 0 1 1 1 1 C2H2 zinc-finger DUF4201 PF13870.6 EMG48726.1 - 0.00021 21.1 0.3 0.00044 20.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) zinc_ribbon_10 PF10058.9 EMG48726.1 - 0.18 11.6 3.0 0.82 9.5 0.3 2.5 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-LITAF-like PF10601.9 EMG48726.1 - 8.8 6.7 9.9 14 6.0 1.3 2.5 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain LSM PF01423.22 EMG48727.1 - 1e-18 66.8 0.3 1.4e-18 66.4 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EMG48727.1 - 0.048 13.8 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.8 EMG48727.1 - 0.072 13.0 0.1 0.23 11.4 0.1 1.8 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) Hfq PF17209.3 EMG48727.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Peptidase_C1_2 PF03051.15 EMG48728.1 - 1.9e-154 514.7 6.6 2.3e-154 514.4 6.6 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EMG48728.1 - 4.6e-06 26.9 0.6 0.00081 19.5 0.2 2.9 2 1 0 2 2 2 2 Papain family cysteine protease DUF740 PF05340.12 EMG48729.1 - 0.4 9.4 9.4 0.44 9.2 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Leu_zip PF15294.6 EMG48730.1 - 0.012 15.1 0.3 0.012 15.1 0.3 1.6 2 0 0 2 2 2 0 Leucine zipper HALZ PF02183.18 EMG48730.1 - 0.052 13.8 0.8 0.11 12.7 0.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 EMG48730.1 - 0.14 12.0 2.3 0.33 10.8 2.3 1.7 1 0 0 1 1 1 0 Septum formation initiator Cnn_1N PF07989.11 EMG48730.1 - 1.8 8.8 8.8 0.11 12.6 1.2 2.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 UAF_Rrn10 PF05234.11 EMG48731.1 - 1.1e-11 45.0 0.2 2.9e-11 43.7 0.2 1.7 1 1 0 1 1 1 1 UAF complex subunit Rrn10 Methyltr_RsmB-F PF01189.17 EMG48732.1 - 4.9e-38 130.8 0.0 2.1e-37 128.7 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EMG48732.1 - 0.00019 21.6 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MSA-2c PF12238.8 EMG48732.1 - 8.8 6.3 8.6 4.4 7.2 2.1 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c Palm_thioest PF02089.15 EMG48733.1 - 5.6e-81 272.0 0.0 6.4e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 EMG48733.1 - 0.00063 19.3 0.0 0.012 15.1 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 2) FSH1 PF03959.13 EMG48733.1 - 0.0014 18.3 0.4 0.034 13.8 0.4 2.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF676 PF05057.14 EMG48733.1 - 0.0044 16.5 0.0 0.0071 15.9 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EMG48733.1 - 0.045 13.5 0.1 0.19 11.5 0.0 1.9 2 1 0 2 2 2 0 PGAP1-like protein Lyase_1 PF00206.20 EMG48734.1 - 4.5e-10 39.4 0.0 5e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Lyase Adaptin_N PF01602.20 EMG48736.1 - 6.8e-100 335.1 8.8 9.7e-100 334.6 8.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EMG48736.1 - 1.2e-57 193.4 0.1 9.4e-57 190.5 0.0 2.5 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EMG48736.1 - 3e-54 182.7 0.8 3e-54 182.7 0.8 2.1 2 0 0 2 2 2 1 Coatomer beta C-terminal region Cnd1 PF12717.7 EMG48736.1 - 8e-11 42.3 7.5 5e-08 33.1 0.1 3.0 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMG48736.1 - 7.1e-10 39.2 0.6 8.3e-06 26.1 0.0 5.0 4 2 2 6 6 6 1 HEAT repeats HEAT PF02985.22 EMG48736.1 - 6.7e-05 22.8 0.3 0.19 12.0 0.0 5.3 6 0 0 6 6 6 1 HEAT repeat Coatomer_g_Cpla PF16381.5 EMG48736.1 - 0.00023 21.3 0.0 0.0019 18.3 0.0 2.5 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform DUF5578 PF17741.1 EMG48736.1 - 0.011 15.2 5.7 0.11 11.8 0.5 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5578) HEAT_EZ PF13513.6 EMG48736.1 - 0.029 14.9 0.2 5.9 7.5 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat AP4E_app_platf PF14807.6 EMG48736.1 - 0.099 13.0 0.1 0.099 13.0 0.1 2.8 3 1 0 3 3 3 0 Adaptin AP4 complex epsilon appendage platform Ribosomal_L7Ae PF01248.26 EMG48737.1 - 2.6e-26 91.2 0.4 4.4e-26 90.4 0.3 1.4 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EMG48737.1 - 0.00095 19.2 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 zf-UBR PF02207.20 EMG48738.1 - 2.9e-14 53.0 10.1 2.9e-14 53.0 10.1 1.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-AD PF07776.15 EMG48738.1 - 0.056 13.7 4.7 3 8.2 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Lon_C PF05362.13 EMG48739.1 - 1.6e-65 220.5 0.0 4.2e-65 219.2 0.0 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EMG48739.1 - 1e-26 94.1 3.0 1e-26 94.1 3.0 2.6 2 1 1 3 3 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EMG48739.1 - 6.1e-21 75.2 0.1 3.5e-20 72.8 0.0 2.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMG48739.1 - 1.3e-08 34.9 0.0 5.3e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 EMG48739.1 - 8.4e-06 24.9 0.0 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 EMG48739.1 - 1.2e-05 25.1 0.1 0.00051 19.8 0.0 2.8 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain ChlI PF13541.6 EMG48739.1 - 1.5e-05 24.9 0.0 4.4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EMG48739.1 - 2.2e-05 24.9 0.3 0.00019 21.8 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMG48739.1 - 0.00013 22.2 0.0 0.00096 19.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMG48739.1 - 0.00018 22.1 0.0 0.0033 18.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EMG48739.1 - 0.00036 19.8 0.1 0.0014 18.0 0.1 1.9 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EMG48739.1 - 0.00074 19.3 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EMG48739.1 - 0.00098 19.0 0.1 0.015 15.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EMG48739.1 - 0.0023 17.4 0.1 0.04 13.3 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EMG48739.1 - 0.0025 17.6 0.0 0.0085 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EMG48739.1 - 0.0033 17.4 0.0 0.033 14.1 0.0 2.5 1 1 1 2 2 2 1 NTPase NACHT PF05729.12 EMG48739.1 - 0.0049 16.8 0.0 0.2 11.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 EMG48739.1 - 0.0087 16.4 0.4 0.17 12.2 0.4 2.8 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 EMG48739.1 - 0.018 14.4 0.7 0.056 12.7 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 EMG48739.1 - 0.019 15.3 0.0 0.073 13.5 0.0 2.1 1 0 0 1 1 1 0 RNA helicase MazG_C PF18722.1 EMG48739.1 - 0.023 14.2 0.4 0.058 12.9 0.4 1.7 1 0 0 1 1 1 0 MazG C-terminal domain AAA_33 PF13671.6 EMG48739.1 - 0.028 14.6 0.1 0.097 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EMG48739.1 - 0.028 14.4 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 EMG48739.1 - 0.031 14.0 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 Cytidylate kinase AAA_7 PF12775.7 EMG48739.1 - 0.083 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EMG48739.1 - 0.13 12.0 0.4 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 EMG48739.1 - 0.13 12.5 3.4 0.54 10.5 0.0 3.3 4 0 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.25 EMG48739.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.6 EMG48739.1 - 0.34 10.7 0.0 0.34 10.7 0.0 3.9 4 0 0 4 4 4 0 AAA domain DDHD PF02862.17 EMG48739.1 - 1.9 8.6 7.6 31 4.6 0.4 3.2 3 0 0 3 3 3 0 DDHD domain RNA_pol_Rpc4 PF05132.14 EMG48739.1 - 2.4 8.6 13.8 1.3 9.4 5.1 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 TOM13 PF08219.11 EMG48740.1 - 5.2e-27 93.6 0.0 6.9e-27 93.2 0.0 1.3 1 0 0 1 1 1 1 Outer membrane protein TOM13 Hexokinase_2 PF03727.16 EMG48741.1 - 3e-80 269.1 0.0 7.7e-80 267.8 0.0 1.6 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 EMG48741.1 - 8.6e-70 234.7 0.0 1.3e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DIOX_N PF14226.6 EMG48742.1 - 2.3e-32 112.2 0.0 5e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMG48742.1 - 4.2e-16 59.3 0.0 7.6e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF5315 PF17242.2 EMG48743.1 - 1.5e-21 76.0 0.8 1.5e-21 76.0 0.8 1.8 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Pro-NT_NN PF07421.11 EMG48743.1 - 0.84 9.9 7.6 0.9 9.8 6.5 1.5 1 1 0 1 1 1 0 Neurotensin/neuromedin N precursor WD40 PF00400.32 EMG48744.1 - 6.2e-59 194.6 17.6 5.8e-12 45.9 0.7 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EMG48744.1 - 2.7e-43 147.3 0.4 2.7e-43 147.3 0.4 2.0 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EMG48744.1 - 9.1e-14 51.5 0.1 0.073 13.4 0.0 5.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMG48744.1 - 4.7e-08 32.1 4.9 0.0025 16.5 0.1 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EMG48744.1 - 2.6e-06 27.0 0.0 2 7.7 0.0 4.2 4 0 0 4 4 4 3 WD40-like domain LisH PF08513.11 EMG48744.1 - 9.5e-06 25.4 0.1 2.9e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 EMG48744.1 - 9.5e-06 25.6 0.1 0.017 15.0 0.0 3.3 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EMG48744.1 - 7.7e-05 21.8 0.3 8.3 5.3 0.0 4.5 3 2 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EMG48744.1 - 0.008 16.1 0.1 8.6 6.4 0.0 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat TFIIA PF03153.13 EMG48744.1 - 0.063 13.3 41.1 0.1 12.6 22.2 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RIFIN PF02009.16 EMG48745.1 - 2.2 8.1 7.1 2.4 8.0 7.1 1.1 1 0 0 1 1 1 0 Rifin GDWWSH PF15667.5 EMG48745.1 - 2.9 7.3 13.8 3.6 7.0 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function with motif GDWWSH Macoilin PF09726.9 EMG48745.1 - 8.5 4.8 19.3 9.6 4.6 19.3 1.1 1 0 0 1 1 1 0 Macoilin family SRP1_TIP1 PF00660.17 EMG48746.1 - 3.5e-21 75.1 0.1 6.2e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Seripauperin and TIP1 family SprA-related PF12118.8 EMG48746.1 - 0.64 9.1 12.5 0.88 8.7 12.5 1.1 1 0 0 1 1 1 0 SprA-related family Herpes_capsid PF06112.11 EMG48746.1 - 2.1 8.4 17.5 4 7.5 17.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein FAM199X PF15814.5 EMG48746.1 - 5.1 6.0 11.6 8 5.4 11.6 1.4 1 0 0 1 1 1 0 Protein family FAM199X Atg14 PF10186.9 EMG48747.1 - 1.1e-06 27.9 14.4 1.1e-05 24.6 14.4 2.1 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 EMG48747.1 - 0.0021 18.1 7.8 0.0053 16.7 0.1 2.6 3 0 0 3 3 3 1 Apg6 BARA domain Snapin_Pallidin PF14712.6 EMG48747.1 - 0.026 14.9 13.4 0.18 12.2 1.4 3.5 1 1 2 3 3 3 0 Snapin/Pallidin CENP-F_leu_zip PF10473.9 EMG48747.1 - 0.097 12.7 8.5 0.067 13.2 6.5 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 EMG48747.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation Ribosomal_L27A PF00828.19 EMG48747.1 - 0.44 11.2 1.6 1 10.1 1.6 1.6 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pim PF16765.5 EMG48747.1 - 1.3 9.2 5.6 26 5.1 0.6 3.3 2 1 1 3 3 3 0 Pesticin immunity protein DUF3450 PF11932.8 EMG48747.1 - 1.8 7.8 7.3 2.1 7.6 4.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 EMG48747.1 - 2.4 8.6 12.0 6.9 7.2 2.6 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SNF2_N PF00176.23 EMG48748.1 - 5e-63 212.9 0.6 9e-63 212.1 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EMG48748.1 - 5.3e-48 162.8 19.9 5.3e-48 162.8 19.9 2.4 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.31 EMG48748.1 - 3.4e-19 69.2 2.0 9.9e-19 67.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG48748.1 - 5.5e-06 26.5 0.0 5.5e-06 26.5 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Fe_hyd_lg_C PF02906.14 EMG48748.1 - 1.2 8.7 5.2 0.47 10.1 2.4 1.7 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain PNP_phzG_C PF10590.9 EMG48749.1 - 4.6e-18 65.0 2.2 9.1e-18 64.1 2.2 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EMG48749.1 - 3.5e-10 39.9 0.0 5.3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GEP5 PF17053.5 EMG48749.1 - 0.003 17.4 0.1 0.0039 17.1 0.1 1.2 1 0 0 1 1 1 1 Genetic interactor of prohibitin 5 Pyridox_oxase_2 PF12766.7 EMG48749.1 - 0.1 13.2 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Ribosomal_L32p PF01783.23 EMG48750.1 - 2.8e-14 53.1 3.9 4.6e-14 52.4 3.9 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family Stc1 PF12898.7 EMG48750.1 - 0.012 16.2 1.5 0.02 15.5 0.7 1.8 2 0 0 2 2 2 0 Stc1 domain GATase_4 PF13230.6 EMG48750.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II zf-ribbon_3 PF13248.6 EMG48750.1 - 0.33 10.4 1.9 0.64 9.5 1.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Septin PF00735.18 EMG48751.1 - 1.2e-111 372.5 0.6 1.5e-111 372.2 0.6 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EMG48751.1 - 3.4e-10 40.0 0.0 6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EMG48751.1 - 1.2e-06 28.0 0.9 2.1e-06 27.2 0.9 1.5 1 1 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EMG48751.1 - 1.4e-06 28.3 2.0 1.7e-06 28.1 0.6 1.8 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EMG48751.1 - 2.7e-05 23.8 0.2 0.00045 19.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 EMG48751.1 - 0.0013 18.0 0.4 0.0026 17.0 0.1 1.6 2 0 0 2 2 2 1 NB-ARC domain Roc PF08477.13 EMG48751.1 - 0.0013 18.9 0.0 0.0044 17.2 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EMG48751.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 EMG48751.1 - 0.0021 18.1 2.2 0.48 10.5 0.6 2.5 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.6 EMG48751.1 - 0.0036 17.6 0.5 0.053 13.8 0.1 2.4 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMG48751.1 - 0.0076 16.7 0.1 0.02 15.3 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain ABC_tran PF00005.27 EMG48751.1 - 0.011 16.2 1.9 0.017 15.6 0.6 2.0 2 1 0 2 2 2 0 ABC transporter Gtr1_RagA PF04670.12 EMG48751.1 - 0.048 13.0 0.2 0.15 11.4 0.2 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region T2SSE PF00437.20 EMG48751.1 - 0.056 12.5 0.3 0.087 11.9 0.3 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EMG48751.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EMG48751.1 - 0.068 12.7 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region IIGP PF05049.13 EMG48751.1 - 0.094 11.8 1.1 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Ras PF00071.22 EMG48751.1 - 0.096 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Ras family PduV-EutP PF10662.9 EMG48751.1 - 0.11 12.2 0.2 1.2 8.8 0.2 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EMG48751.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FeoB_N PF02421.18 EMG48751.1 - 0.28 10.7 1.3 2.4 7.7 0.7 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B XPG_N PF00752.17 EMG48752.1 - 1.3e-32 112.3 0.0 2.2e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EMG48752.1 - 1.9e-27 95.4 0.1 4.3e-27 94.3 0.1 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EMG48752.1 - 1.7e-07 31.7 0.1 8.2e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 EMG48752.1 - 0.099 12.8 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Proteasome PF00227.26 EMG48753.1 - 3.2e-58 196.3 0.0 4e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FumaraseC_C PF10415.9 EMG48754.1 - 9.6e-27 93.2 0.0 1.5e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Fumarase C C-terminus SH3_17 PF18350.1 EMG48754.1 - 0.026 14.4 0.1 0.056 13.3 0.1 1.5 1 0 0 1 1 1 0 Restriction endonuclease SH3 domain GATase_5 PF13507.6 EMG48755.1 - 1.5e-100 335.6 0.0 2.3e-100 335.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EMG48755.1 - 3.5e-38 131.2 0.3 3.9e-28 98.5 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EMG48755.1 - 4.5e-29 100.8 0.0 8.4e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EMG48755.1 - 3.1e-22 78.9 0.0 8.5e-22 77.4 0.0 1.9 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Tmemb_14 PF03647.13 EMG48756.1 - 1.2e-25 90.0 6.0 1.4e-25 89.8 6.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Phage_holin_5_2 PF16079.5 EMG48756.1 - 0.064 13.6 1.8 0.18 12.1 0.0 2.2 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Aim19 PF10315.9 EMG48756.1 - 0.31 11.4 3.2 0.88 9.9 3.2 1.8 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 AA_permease_N PF08403.10 EMG48757.1 - 0.022 14.3 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 Amino acid permease N-terminal Mvb12 PF09452.10 EMG48758.1 - 0.0049 17.3 1.1 0.0091 16.4 1.1 1.5 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 RNA_pol_Rpb8 PF03870.15 EMG48759.1 - 2.2e-43 147.8 0.0 2.5e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EMG48759.1 - 3.3e-06 27.1 0.2 0.028 14.5 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Sporozoite_P67 PF05642.11 EMG48760.1 - 0.12 10.4 3.8 0.14 10.2 3.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PsbN PF02468.15 EMG48760.1 - 0.18 11.7 0.2 0.18 11.7 0.2 1.5 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Orf78 PF06024.12 EMG48760.1 - 0.48 10.7 2.8 0.22 11.8 0.5 1.7 2 0 0 2 2 2 0 Orf78 (ac78) MAP17 PF15807.5 EMG48760.1 - 0.64 10.3 3.1 6.7 7.0 3.0 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CDC45 PF02724.14 EMG48760.1 - 0.71 8.1 7.3 0.84 7.8 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EMG48760.1 - 0.81 8.8 5.8 2.4 7.3 5.8 1.7 1 1 1 2 2 2 0 ZIP Zinc transporter DUF2076 PF09849.9 EMG48760.1 - 1.5 8.8 8.5 1.9 8.5 8.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) NOA36 PF06524.12 EMG48760.1 - 3.1 7.0 11.3 3.7 6.8 11.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF5423 PF17461.2 EMG48760.1 - 3.8 6.3 6.0 5.7 5.7 6.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) MFS_1 PF07690.16 EMG48761.1 - 3.3e-05 23.0 26.1 0.0001 21.3 24.9 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Na_trans_cytopl PF11933.8 EMG48761.1 - 0.096 12.5 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Cytoplasmic domain of voltage-gated Na+ ion channel DUF2462 PF09495.10 EMG48762.1 - 6.1e-20 71.7 11.9 6.1e-20 71.7 11.9 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Ribosomal_S3_C PF00189.20 EMG48763.1 - 2.4e-23 82.4 0.7 1.1e-22 80.3 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EMG48763.1 - 6.7e-09 35.5 0.2 1.4e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 KH domain Mannosyl_trans3 PF11051.8 EMG48764.1 - 2.1e-52 178.2 0.2 4.5e-52 177.1 0.2 1.6 1 0 0 1 1 1 1 Mannosyltransferase putative PP2C PF00481.21 EMG48765.1 - 3e-54 184.4 0.0 3.8e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EMG48765.1 - 0.0072 16.0 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Exo_endo_phos PF03372.23 EMG48767.1 - 9.6e-15 54.7 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spindle_Spc25 PF08234.12 EMG48768.1 - 3.5e-22 78.4 2.3 1.8e-21 76.1 2.3 2.3 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 EMG48768.1 - 1.1e-05 24.5 20.9 1.1e-05 24.5 20.9 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF4686 PF15742.5 EMG48768.1 - 0.00035 19.8 24.3 0.00035 19.8 24.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4686) DUF1451 PF07295.11 EMG48768.1 - 0.02 14.9 2.6 0.02 14.9 2.6 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain She9_MDM33 PF05546.11 EMG48768.1 - 0.032 14.0 11.7 0.048 13.5 10.7 1.8 1 1 0 1 1 1 0 She9 / Mdm33 family DUF2935 PF11155.8 EMG48768.1 - 0.04 14.2 6.0 0.37 11.1 6.0 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) HAUS-augmin3 PF14932.6 EMG48768.1 - 0.083 12.5 17.8 0.15 11.6 17.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Prominin PF05478.11 EMG48768.1 - 0.12 10.3 16.0 0.16 9.9 16.0 1.2 1 0 0 1 1 1 0 Prominin Atg14 PF10186.9 EMG48768.1 - 0.13 11.3 21.1 0.29 10.2 21.1 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 EMG48768.1 - 0.43 10.6 14.3 0.51 10.4 11.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 EMG48768.1 - 0.69 7.8 12.3 0.93 7.3 12.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.6 EMG48768.1 - 0.7 10.2 15.3 4.2 7.7 9.8 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) LMBR1 PF04791.16 EMG48768.1 - 0.72 8.7 9.8 0.82 8.5 9.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 EMG48768.1 - 1.6 8.0 21.3 0.28 10.5 14.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UPF0184 PF03670.13 EMG48768.1 - 1.8 9.0 14.7 1.6 9.2 7.7 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) ThiD2 PF17792.1 EMG48768.1 - 2.7 8.5 9.8 1.4 9.4 4.8 2.4 2 1 1 3 3 3 0 ThiD2 family IFT57 PF10498.9 EMG48768.1 - 3.4 6.6 23.3 2.6 6.9 0.8 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF948 PF06103.11 EMG48768.1 - 3.4 8.0 12.6 7.2 6.9 4.6 3.1 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) STAT_alpha PF01017.20 EMG48768.1 - 6.9 6.5 21.6 42 4.0 21.1 2.1 1 1 1 2 2 2 0 STAT protein, all-alpha domain DUF4407 PF14362.6 EMG48768.1 - 8.2 5.7 13.4 15 4.8 13.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EMG48768.1 - 9.8 6.2 17.9 0.63 10.1 3.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Presenilin PF01080.17 EMG48769.1 - 0.0017 17.2 4.1 0.0023 16.8 4.1 1.1 1 0 0 1 1 1 1 Presenilin Pro_isomerase PF00160.21 EMG48769.1 - 0.011 16.0 3.3 0.021 15.1 0.0 2.7 2 2 0 2 2 2 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BUD22 PF09073.10 EMG48769.1 - 0.042 13.2 10.9 0.051 12.9 10.9 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EMG48769.1 - 0.075 11.3 7.1 0.098 10.9 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 EMG48769.1 - 0.077 13.2 18.0 0.16 12.2 18.0 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 MRNIP PF15749.5 EMG48769.1 - 0.27 12.0 5.0 0.64 10.8 5.0 1.7 1 0 0 1 1 1 0 MRN-interacting protein Zip PF02535.22 EMG48769.1 - 0.31 10.2 1.3 0.42 9.8 1.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PPP4R2 PF09184.11 EMG48769.1 - 0.33 10.5 18.1 0.51 9.9 18.1 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 EMG48769.1 - 2.2 6.4 23.2 2.8 6.0 23.2 1.1 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 EMG48769.1 - 2.2 8.5 14.2 3.8 7.7 14.2 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 EMG48769.1 - 3.8 6.8 20.0 4.8 6.5 20.0 1.1 1 0 0 1 1 1 0 SDA1 Yuri_gagarin PF15934.5 EMG48771.1 - 0.0089 15.9 3.9 0.0089 15.9 3.9 1.4 2 0 0 2 2 2 1 Yuri gagarin APG6_N PF17675.1 EMG48771.1 - 2 8.9 11.5 0.12 12.9 5.5 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region ATP-synt_ab PF00006.25 EMG48772.1 - 1.2e-66 224.4 0.0 1.6e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EMG48772.1 - 2.8e-14 53.4 1.3 5.5e-14 52.4 1.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain G-alpha PF00503.20 EMG48774.1 - 0.018 14.2 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Roc PF08477.13 EMG48774.1 - 0.084 13.1 0.0 0.19 12.0 0.0 1.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_130 PF04041.13 EMG48775.1 - 1e-41 142.9 0.0 1.2e-41 142.7 0.0 1.0 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_32N PF00251.20 EMG48775.1 - 2e-08 34.2 1.3 2.2e-06 27.4 0.0 2.6 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain DUF3999 PF13163.6 EMG48775.1 - 0.046 12.9 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3999) VPS9 PF02204.18 EMG48776.1 - 5.9e-15 55.4 0.7 4.1e-14 52.7 0.1 2.7 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Pro-rich PF15240.6 EMG48777.1 - 0.0035 17.7 23.0 0.0047 17.2 23.0 1.3 1 0 0 1 1 1 1 Proline-rich Aconitase PF00330.20 EMG48779.1 - 1.4e-152 509.0 0.0 1.7e-152 508.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMG48779.1 - 4.9e-42 143.4 0.1 8.8e-42 142.5 0.1 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain LRR_8 PF13855.6 EMG48780.1 - 1.4e-05 24.7 13.4 0.012 15.3 1.4 3.6 2 1 1 3 3 3 3 Leucine rich repeat F-box-like PF12937.7 EMG48780.1 - 0.00014 21.7 0.3 0.00047 20.0 0.3 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EMG48780.1 - 0.00054 19.8 0.3 0.0019 18.0 0.1 2.1 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 EMG48780.1 - 0.16 12.4 13.7 0.43 11.1 3.3 3.5 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) SF3A3 PF16837.5 EMG48780.1 - 0.2 12.2 4.1 2.8 8.5 0.5 3.0 2 1 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 LRR_1 PF00560.33 EMG48780.1 - 2.8 8.9 5.0 1.1e+02 4.0 1.4 4.0 2 1 0 2 2 2 0 Leucine Rich Repeat PEMT PF04191.13 EMG48781.1 - 5.1e-58 194.0 12.6 3.6e-35 120.6 2.3 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 EMG48781.1 - 0.0042 17.6 0.5 0.044 14.3 0.5 2.6 2 0 0 2 2 2 1 SKICH domain RNase_PH PF01138.21 EMG48782.1 - 2.4e-27 96.0 0.0 4.5e-27 95.1 0.0 1.4 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 OPT PF03169.15 EMG48783.1 - 6e-165 550.4 38.7 7e-165 550.2 38.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 EMG48784.1 - 6.4e-157 523.8 34.3 7.4e-157 523.6 34.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cnd1 PF12717.7 EMG48785.1 - 7.3e-05 22.9 1.6 0.00031 20.8 0.5 2.1 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EMG48785.1 - 0.0048 16.5 0.3 0.03 13.9 0.3 2.0 2 0 0 2 2 2 1 CLASP N terminal Proteasom_PSMB PF10508.9 EMG48785.1 - 0.0077 14.8 1.9 0.011 14.2 1.9 1.2 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Glyco_hydro_38 PF18438.1 EMG48785.1 - 0.019 15.0 0.1 0.3 11.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain 1 HEAT PF02985.22 EMG48785.1 - 0.041 14.2 0.0 22 5.7 0.0 3.6 4 0 0 4 4 4 0 HEAT repeat zf-C2H2 PF00096.26 EMG48786.1 - 4.6e-20 70.9 27.7 3e-05 24.2 0.5 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMG48786.1 - 3.3e-18 65.2 36.3 4.8e-08 33.1 0.6 4.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMG48786.1 - 1.2e-11 44.3 23.5 0.0047 17.7 0.3 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 EMG48786.1 - 0.00099 19.4 0.1 0.00099 19.4 0.1 4.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EMG48786.1 - 0.0043 17.0 2.8 0.0043 17.0 2.8 4.5 5 0 0 5 5 5 2 C2H2-type zinc finger zf-Di19 PF05605.12 EMG48786.1 - 0.012 15.8 9.5 0.054 13.8 5.4 2.8 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EMG48786.1 - 0.096 13.0 0.1 0.096 13.0 0.1 5.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding RNA_pol_L_2 PF13656.6 EMG48787.1 - 4.6e-32 109.6 0.0 6.3e-32 109.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EMG48787.1 - 5e-16 57.9 0.0 7e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DEAD PF00270.29 EMG48788.1 - 1.7e-48 164.7 0.0 6e-48 162.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG48788.1 - 1e-27 96.7 0.0 3.2e-27 95.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG48788.1 - 3.6e-05 23.8 0.0 7.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EMG48788.1 - 0.0023 18.3 0.0 1.3 9.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EMG48788.1 - 0.0036 17.1 0.0 0.28 10.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain UTP25 PF06862.12 EMG48788.1 - 0.015 14.1 0.0 0.19 10.4 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Peptidase_S8 PF00082.22 EMG48789.1 - 8.9e-14 51.4 5.9 2.1e-13 50.2 5.9 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMG48789.1 - 0.00087 19.9 0.1 0.0051 17.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 Hyphal_reg_CWP PF11765.8 EMG48790.1 - 2.2e-106 355.6 8.0 5e-106 354.4 8.0 1.6 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal ETRAMP PF09716.10 EMG48790.1 - 0.17 12.0 0.2 0.68 10.0 0.2 2.0 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Acetyltransf_1 PF00583.25 EMG48792.1 - 3.1e-08 33.9 0.0 4.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMG48792.1 - 6.2e-08 33.0 0.0 1.8e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMG48792.1 - 2.3e-07 30.8 0.0 3.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMG48792.1 - 0.00019 21.3 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EMG48792.1 - 0.0075 16.3 0.1 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain OPT PF03169.15 EMG48793.1 - 9.6e-142 473.7 44.9 1.1e-141 473.5 44.9 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SID PF11778.8 EMG48793.1 - 7.3e-05 22.9 0.1 0.00022 21.4 0.1 1.8 1 0 0 1 1 1 1 Septation initiation Flagellin_N PF00669.20 EMG48793.1 - 0.022 14.9 0.2 0.24 11.5 0.9 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4064 PF13273.6 EMG48793.1 - 0.027 14.7 0.0 0.027 14.7 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF4064) MCPsignal PF00015.21 EMG48793.1 - 0.45 10.3 4.1 0.41 10.4 2.8 1.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.11 EMG48793.1 - 0.62 8.9 20.1 1.4 7.7 20.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 EMG48793.1 - 2 8.7 23.7 13 6.1 7.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Jnk-SapK_ap_N PF09744.9 EMG48793.1 - 2.1 8.6 23.5 4.1 7.6 23.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 EMG48793.1 - 2.4 7.2 15.5 4 6.4 15.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 EMG48793.1 - 4.4 7.6 5.7 2.5 8.4 2.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Bax1-I PF01027.20 EMG48794.1 - 3e-49 167.7 30.6 3.5e-49 167.5 30.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 EMG48794.1 - 4e-07 29.8 8.1 6.2e-07 29.2 8.1 1.4 1 0 0 1 1 1 1 Bax inhibitor 1 like Collagen PF01391.18 EMG48795.1 - 0.17 11.7 11.7 0.37 10.6 11.7 1.7 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Astro_capsid_p PF12226.8 EMG48796.1 - 4.5 6.3 7.5 5.8 6.0 7.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Peptidase_S8 PF00082.22 EMG48797.1 - 5.2e-07 29.2 0.0 5.2e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Subtilase family ICE2 PF08426.10 EMG48798.1 - 9.3e-116 387.3 11.9 1.3e-115 386.8 11.9 1.2 1 0 0 1 1 1 1 ICE2 HNF-1_N PF04814.13 EMG48798.1 - 1.9 9.1 8.1 2.9 8.4 8.1 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus SR-25 PF10500.9 EMG48798.1 - 3.3 7.3 16.2 5 6.7 16.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EMG48798.1 - 6.4 7.5 13.2 10 6.8 13.2 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF1776 PF08643.10 EMG48799.1 - 5.8e-98 327.9 0.4 7.6e-98 327.5 0.4 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) STE2 PF02116.15 EMG48800.1 - 3.3e-80 269.4 21.0 4.2e-80 269.0 21.0 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Cytochrom_B_C PF00032.17 EMG48800.1 - 0.9 9.9 5.9 3.6 7.9 0.2 2.8 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD RGS PF00615.19 EMG48801.1 - 2.2e-07 31.1 0.2 4.6e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain FNIP PF05725.12 EMG48802.1 - 0.62 10.3 13.5 3 8.1 0.2 4.2 3 0 0 3 3 3 0 FNIP Repeat HMG_box PF00505.19 EMG48804.1 - 2.5e-17 63.0 0.5 2.5e-17 63.0 0.5 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMG48804.1 - 5.1e-08 33.4 4.9 6.7e-08 33.0 0.1 2.8 2 0 0 2 2 2 1 HMG-box domain COX4 PF02936.14 EMG48804.1 - 0.028 14.4 0.1 0.028 14.4 0.1 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Pantoate_ligase PF02569.15 EMG48805.1 - 4.8e-88 294.8 0.0 5.5e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Phage_connector PF05352.12 EMG48805.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.6 1 1 0 1 1 1 0 Phage Connector (GP10) HA2 PF04408.23 EMG48806.1 - 1.3e-21 76.9 0.2 5.1e-20 71.8 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMG48806.1 - 6.3e-15 55.5 0.1 3e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMG48806.1 - 3.9e-14 52.8 0.3 1.2e-13 51.2 0.3 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EMG48806.1 - 8.3e-09 35.5 0.8 2.5e-08 33.9 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMG48806.1 - 7.4e-07 29.5 0.1 2.4e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EMG48806.1 - 0.00023 21.1 0.0 0.00047 20.2 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 EMG48806.1 - 0.0031 17.9 0.1 0.008 16.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EMG48806.1 - 0.0041 16.4 0.0 0.0041 16.4 0.0 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EMG48806.1 - 0.022 14.1 0.1 0.052 12.9 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 EMG48806.1 - 0.03 14.4 1.0 2.8 8.0 1.0 3.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EMG48806.1 - 0.037 13.7 0.1 0.088 12.4 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 EMG48806.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein HSF_DNA-bind PF00447.17 EMG48806.1 - 0.062 13.9 0.1 0.24 12.0 0.1 2.0 1 0 0 1 1 1 0 HSF-type DNA-binding AAA_30 PF13604.6 EMG48806.1 - 0.098 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMG48806.1 - 0.32 11.5 4.2 0.39 11.2 0.2 2.9 2 1 0 2 2 2 0 ABC transporter Chordopox_A13L PF05961.11 EMG48806.1 - 0.73 10.1 3.0 4.8 7.5 0.3 3.3 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Nup54 PF13874.6 EMG48807.1 - 5.7e-38 130.2 0.1 1.5e-37 128.9 0.1 1.7 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 EMG48807.1 - 6.2e-24 84.7 141.2 4.5e-08 33.8 44.3 4.4 1 1 3 4 4 4 4 Nucleoporin FG repeat region Cnd1 PF12717.7 EMG48807.1 - 0.0086 16.1 1.7 0.021 14.8 0.4 2.0 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 CX9C PF16860.5 EMG48808.1 - 0.00039 20.4 1.4 0.00039 20.4 1.4 2.2 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Colipase-like PF15083.6 EMG48808.1 - 0.13 12.4 3.4 0.21 11.8 3.4 1.3 1 0 0 1 1 1 0 Colipase-like CHCH PF06747.13 EMG48808.1 - 0.27 11.4 12.0 0.078 13.1 4.4 2.8 3 0 0 3 3 3 0 CHCH domain COX6B PF02297.17 EMG48808.1 - 3.6 7.9 11.0 1.7 8.9 4.3 2.4 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb COG2 PF06148.11 EMG48809.1 - 3.8e-12 46.5 0.5 7.7e-12 45.5 0.5 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Recep_L_domain PF01030.24 EMG48809.1 - 0.016 15.3 2.5 0.016 15.3 2.5 1.8 1 1 0 1 1 1 0 Receptor L domain Vps51 PF08700.11 EMG48809.1 - 0.082 13.0 0.4 0.082 13.0 0.4 1.8 2 0 0 2 2 2 0 Vps51/Vps67 Fungal_trans PF04082.18 EMG48810.1 - 1.3e-36 126.0 1.7 1.3e-36 126.0 1.7 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG48810.1 - 1e-09 38.3 11.1 1e-09 38.3 11.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pigment_DH PF06324.11 EMG48810.1 - 0.029 14.4 0.1 0.096 12.8 0.1 1.9 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) DUF5558 PF17713.1 EMG48810.1 - 0.1 13.0 1.7 0.19 12.1 1.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5558) Abhydrolase_6 PF12697.7 EMG48811.1 - 3.9e-13 50.5 0.0 5.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMG48811.1 - 6e-10 38.8 0.0 1e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EMG48811.1 - 1.7e-05 24.6 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 EMG48811.1 - 0.001 18.8 0.1 0.0025 17.5 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMG48811.1 - 0.0049 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 EMG48811.1 - 0.006 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_2 PF02230.16 EMG48811.1 - 0.014 15.3 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 EMG48811.1 - 0.036 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Ribosomal_S19 PF00203.21 EMG48811.1 - 0.15 12.0 0.0 1.3 8.9 0.0 2.5 3 0 0 3 3 3 0 Ribosomal protein S19 Lyase_1 PF00206.20 EMG48813.1 - 2.5e-24 86.2 0.0 3.5e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EMG48813.1 - 8.7e-17 61.4 0.0 2.9e-16 59.8 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 EMG48813.1 - 0.067 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) DASH_Dad3 PF08656.10 EMG48814.1 - 2.3e-21 75.7 5.1 3.1e-21 75.2 5.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 DUF3461 PF11944.8 EMG48814.1 - 0.088 12.9 0.6 0.088 12.9 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) UPF0121 PF03661.13 EMG48815.1 - 0.0065 15.9 15.3 0.13 11.7 8.3 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0121) WD40 PF00400.32 EMG48816.1 - 1.9e-19 69.6 16.4 2.7e-05 24.9 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG48816.1 - 5.4e-12 45.9 0.0 0.0015 18.8 0.0 4.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EMG48816.1 - 4.7e-08 32.8 3.4 0.055 13.4 0.0 4.9 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EMG48816.1 - 5.7e-06 25.5 0.0 1.2 8.0 0.0 4.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 EMG48816.1 - 0.015 14.1 0.3 8.5 5.0 0.0 3.4 2 1 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Frtz PF11768.8 EMG48816.1 - 0.033 12.5 0.0 0.049 11.9 0.0 1.3 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Cation_efflux PF01545.21 EMG48817.1 - 8e-23 81.2 13.8 1e-22 80.9 13.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EMG48817.1 - 0.00098 19.2 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Zn_clus PF00172.18 EMG48818.1 - 0.00023 21.2 11.0 0.00041 20.4 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L30 PF00327.20 EMG48819.1 - 3.4e-08 33.2 0.5 3.4e-08 33.2 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Lge1 PF11488.8 EMG48820.1 - 4.5e-20 71.6 4.9 8.1e-20 70.8 4.9 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 adh_short PF00106.25 EMG48821.1 - 1.9e-33 115.6 0.5 2.4e-33 115.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG48821.1 - 5.2e-18 65.5 0.0 7.2e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG48821.1 - 8.7e-05 22.5 0.1 0.002 18.1 0.0 2.2 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EMG48821.1 - 0.024 13.8 0.5 0.032 13.4 0.5 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1863 PF08937.11 EMG48821.1 - 0.037 14.3 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) DnaJ_C PF01556.18 EMG48822.1 - 7.4e-39 133.2 0.1 9.5e-39 132.8 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMG48822.1 - 1.4e-23 82.8 0.9 2.1e-23 82.2 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain Malate_DH PF12434.8 EMG48822.1 - 0.11 12.6 0.2 0.27 11.3 0.2 1.7 1 0 0 1 1 1 0 Malate dehydrogenase enzyme WD40 PF00400.32 EMG48823.1 - 1.3e-44 149.2 19.3 1.6e-10 41.4 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG48823.1 - 1.1e-14 54.5 4.3 0.0036 17.6 0.1 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMG48823.1 - 2e-09 36.9 1.3 0.018 14.0 0.1 4.4 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EMG48823.1 - 1.1e-08 34.2 14.9 0.0056 15.4 0.3 5.0 3 1 1 5 5 5 4 Nucleoporin Nup120/160 VID27 PF08553.10 EMG48823.1 - 3.3e-06 26.4 0.0 0.0052 15.9 0.0 2.5 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 EMG48823.1 - 3e-05 23.0 2.3 0.49 9.1 0.0 3.8 1 1 1 3 3 3 2 Nup133 N terminal like PALB2_WD40 PF16756.5 EMG48823.1 - 0.00016 20.7 2.2 0.002 17.1 0.0 3.0 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 EMG48823.1 - 0.00048 18.6 0.1 0.0039 15.6 0.0 2.1 1 1 2 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 EMG48823.1 - 0.0013 18.5 10.3 0.24 11.1 0.1 4.7 2 1 3 5 5 5 2 TUP1-like enhancer of split NUP214 PF16755.5 EMG48823.1 - 0.0054 16.0 0.1 0.01 15.1 0.0 1.4 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 WD40_3 PF15911.5 EMG48823.1 - 0.17 11.9 0.9 14 5.7 0.0 3.2 2 1 2 4 4 4 0 WD domain, G-beta repeat SET PF00856.28 EMG48824.1 - 8.3e-06 26.3 0.3 1.3e-05 25.6 0.0 1.6 2 0 0 2 2 2 1 SET domain RFX_DNA_binding PF02257.15 EMG48825.1 - 1e-30 106.2 0.0 2.3e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EMG48825.1 - 0.029 14.8 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 Poxvirus D5 protein-like Cpn60_TCP1 PF00118.24 EMG48826.1 - 5.8e-83 279.2 13.2 1.6e-82 277.7 13.2 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 EMG48826.1 - 0.036 14.4 0.1 0.11 12.9 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator Mito_fiss_reg PF05308.11 EMG48827.1 - 0.012 15.7 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CEP209_CC5 PF16574.5 EMG48828.1 - 0.005 17.0 2.7 0.13 12.4 0.4 2.1 2 0 0 2 2 2 2 Coiled-coil region of centrosome protein CE290 Vps23_core PF09454.10 EMG48828.1 - 0.035 14.1 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Vps23 core domain Integrase_DNA PF02920.15 EMG48828.1 - 0.21 11.3 3.3 2.8 7.7 2.6 2.5 2 1 0 2 2 2 0 DNA binding domain of tn916 integrase Ras PF00071.22 EMG48829.1 - 4.5e-55 185.7 0.5 5.4e-55 185.4 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG48829.1 - 2.4e-38 131.0 0.1 4.6e-38 130.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG48829.1 - 9.8e-15 54.4 0.7 1.2e-14 54.1 0.7 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EMG48829.1 - 3.3e-06 26.6 0.3 4.7e-06 26.1 0.3 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EMG48829.1 - 1.2e-05 25.4 0.0 2.2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMG48829.1 - 1.3e-05 24.8 0.2 0.00015 21.3 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EMG48829.1 - 9.8e-05 21.8 0.6 0.00012 21.5 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EMG48829.1 - 0.00033 20.6 0.9 0.57 10.1 0.3 2.6 1 1 2 3 3 3 2 RsgA GTPase PduV-EutP PF10662.9 EMG48829.1 - 0.0032 17.2 1.2 0.078 12.7 1.2 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EMG48829.1 - 0.017 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DLIC PF05783.11 EMG48829.1 - 0.02 13.7 0.1 2 7.1 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) MazE_antitoxin PF04014.18 EMG48829.1 - 0.046 13.7 0.4 0.1 12.5 0.4 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin FeoB_N PF02421.18 EMG48829.1 - 0.067 12.7 0.2 9.1 5.8 0.2 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B STAT2_C PF12188.8 EMG48829.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal dsDNA_bind PF01984.20 EMG48830.1 - 5.4e-30 103.9 12.2 6.2e-30 103.7 12.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Kinesin PF00225.23 EMG48831.1 - 1.1e-102 343.3 9.1 1.1e-102 343.3 9.1 2.8 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EMG48831.1 - 1.2e-22 80.5 0.2 1.2e-22 80.5 0.2 3.0 4 1 0 4 4 4 1 Microtubule binding AAA_22 PF13401.6 EMG48831.1 - 0.024 14.9 0.5 4.1 7.7 0.0 3.1 2 0 0 2 2 2 0 AAA domain TF_AP-2 PF03299.14 EMG48831.1 - 0.61 10.0 14.3 0.4 10.6 8.7 2.9 2 0 0 2 2 2 0 Transcription factor AP-2 VGPC1_C PF16799.5 EMG48831.1 - 2 8.4 6.2 0.51 10.4 0.4 3.0 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 CLP1_P PF16575.5 EMG48832.1 - 7.4e-46 156.3 0.1 1.2e-45 155.6 0.1 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 EMG48832.1 - 0.00032 20.8 1.0 0.00084 19.4 0.1 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 EMG48832.1 - 0.003 16.9 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_24 PF13479.6 EMG48832.1 - 0.0041 16.9 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EMG48832.1 - 0.012 15.9 0.0 0.092 13.1 0.0 2.6 1 1 0 1 1 1 0 RNA helicase Dynamin_N PF00350.23 EMG48832.1 - 0.016 15.3 1.9 0.022 14.8 0.1 2.1 2 1 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 EMG48832.1 - 0.016 14.7 0.4 4.3 6.8 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Spore_IV_A PF09547.10 EMG48832.1 - 0.036 13.0 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Roc PF08477.13 EMG48832.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EMG48832.1 - 0.063 13.3 0.0 0.24 11.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EMG48832.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 EMG48832.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain GST_N_3 PF13417.6 EMG48833.1 - 6.1e-12 45.8 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMG48833.1 - 6.8e-10 39.2 0.0 2e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMG48833.1 - 1.1e-09 38.1 0.3 2e-09 37.3 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMG48833.1 - 4.5e-09 36.5 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMG48833.1 - 5.4e-09 36.1 0.2 9.9e-09 35.3 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMG48833.1 - 9.6e-08 32.1 0.1 2e-07 31.1 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3658 PF12395.8 EMG48833.1 - 0.0047 16.8 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function GST_C_6 PF17171.4 EMG48833.1 - 0.0084 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Dimer_Tnp_hAT PF05699.14 EMG48833.1 - 0.073 12.9 0.1 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region zf-rbx1 PF12678.7 EMG48834.1 - 3.5e-10 40.0 3.4 6.2e-10 39.2 3.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EMG48834.1 - 5.2e-09 36.3 6.8 2.9e-08 33.9 6.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EMG48834.1 - 1.2e-05 25.1 2.7 0.00046 20.0 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMG48834.1 - 3.1e-05 23.7 2.3 8.1e-05 22.4 2.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EMG48834.1 - 3.7e-05 23.5 3.8 6.6e-05 22.7 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMG48834.1 - 4.3e-05 23.4 1.6 9.3e-05 22.3 1.6 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EMG48834.1 - 0.00012 21.6 0.4 0.00025 20.6 0.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EMG48834.1 - 0.00016 21.4 2.0 0.00016 21.4 2.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG48834.1 - 0.00025 21.0 2.8 0.00054 19.9 2.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EMG48834.1 - 0.0016 18.4 2.6 0.0073 16.3 2.6 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EMG48834.1 - 0.034 14.3 2.4 0.15 12.2 2.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EMG48834.1 - 0.036 14.2 0.6 0.036 14.2 0.6 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING PGA2 PF07543.12 EMG48834.1 - 0.067 13.2 3.3 0.13 12.3 3.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 zf-P11 PF03854.14 EMG48834.1 - 0.24 11.1 2.8 0.32 10.7 0.8 2.0 2 0 0 2 2 2 0 P-11 zinc finger RINGv PF12906.7 EMG48834.1 - 0.89 9.7 3.6 3 8.0 3.6 1.9 1 1 0 1 1 1 0 RING-variant domain RNA_pol_I_TF PF04090.12 EMG48835.1 - 5.2e-59 199.1 3.9 1.1e-58 198.1 3.2 1.9 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor DUF641 PF04859.12 EMG48835.1 - 0.99 9.7 4.4 0.61 10.4 1.5 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Metallophos PF00149.28 EMG48836.1 - 2.1e-34 119.8 0.1 4e-34 118.9 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EMG48836.1 - 2.7e-17 62.9 0.1 5.3e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Med2 PF11214.8 EMG48837.1 - 0.04 14.1 0.3 0.17 12.1 0.1 2.0 2 0 0 2 2 2 0 Mediator complex subunit 2 Fib_alpha PF08702.10 EMG48837.1 - 0.1 12.8 1.0 11 6.2 0.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family zf-C2H2 PF00096.26 EMG48838.1 - 4.4e-09 36.3 19.0 2.6e-05 24.4 1.9 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMG48838.1 - 1.1e-08 35.1 4.8 1.1e-08 35.1 4.8 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMG48838.1 - 5.7e-07 29.8 9.4 0.00012 22.6 1.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMG48838.1 - 6.3e-05 22.9 0.6 6.3e-05 22.9 0.6 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 EMG48838.1 - 0.0025 18.1 0.6 0.0025 18.1 0.6 2.0 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 EMG48838.1 - 0.087 13.3 1.4 0.31 11.5 1.4 2.0 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 EMG48838.1 - 0.12 12.7 0.4 0.12 12.7 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 EMG48838.1 - 0.39 10.6 5.5 0.085 12.7 0.8 2.5 2 1 1 3 3 3 0 GAGA factor CENP-H PF05837.12 EMG48839.1 - 1.6 9.2 15.8 11 6.5 11.5 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Menin PF05053.13 EMG48839.1 - 2.2 6.5 14.9 2.5 6.3 14.9 1.0 1 0 0 1 1 1 0 Menin Pkinase PF00069.25 EMG48841.1 - 3.4e-75 252.8 0.0 3.8e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG48841.1 - 1.3e-30 106.6 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMG48841.1 - 1.8e-05 23.9 0.1 0.00021 20.3 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EMG48841.1 - 0.00016 20.8 0.2 0.00027 20.1 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EMG48841.1 - 0.00039 19.8 0.0 0.0007 19.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EMG48841.1 - 0.0038 17.2 0.0 0.0096 15.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EMG48841.1 - 0.02 14.3 0.1 0.038 13.3 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1892 PF08987.10 EMG48843.1 - 6.8e-14 52.0 2.4 6.8e-14 52.0 2.4 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1892) Nro1 PF12753.7 EMG48843.1 - 0.15 11.0 10.6 0.17 10.8 10.5 1.3 1 1 0 1 1 1 0 Nuclear pore complex subunit Nro1 PDCD2_C PF04194.13 EMG48843.1 - 0.23 11.5 0.0 0.23 11.5 0.0 2.0 1 1 1 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain NOA36 PF06524.12 EMG48843.1 - 0.38 10.0 6.0 0.38 10.0 6.0 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 EMG48843.1 - 0.79 10.1 10.3 1.7 9.0 10.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.13 EMG48843.1 - 1.9 8.3 11.9 1.3 8.8 8.3 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.6 EMG48843.1 - 2.2 8.0 6.3 0.3 10.7 2.5 1.6 2 0 0 2 2 2 0 FAM176 family PGI PF00342.19 EMG48844.1 - 3.9e-241 800.8 1.9 4.5e-241 800.6 1.9 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Mhr1 PF12829.7 EMG48844.1 - 1.9e-05 24.7 0.5 0.14 12.2 0.0 2.9 2 1 1 3 3 3 2 Transcriptional regulation of mitochondrial recombination Nrap_D5 PF17406.2 EMG48844.1 - 0.0058 16.4 0.1 0.72 9.6 0.0 2.3 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Pkinase PF00069.25 EMG48845.1 - 1.8e-49 168.5 0.0 3.7e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG48845.1 - 3.8e-28 98.5 0.0 5.8e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG48845.1 - 0.00064 19.1 0.7 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EMG48845.1 - 0.012 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tcp11 PF05794.13 EMG48846.1 - 1.6e-139 465.9 5.9 1.6e-139 465.9 5.9 1.8 2 1 0 2 2 2 1 T-complex protein 11 DUF3952 PF13130.6 EMG48847.1 - 0.37 11.0 3.4 0.25 11.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) Glyco_hydro_92 PF07971.12 EMG48849.1 - 7.4e-142 473.5 10.5 9.3e-142 473.2 10.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EMG48849.1 - 2.8e-48 164.9 0.4 4.6e-48 164.2 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain HSF_DNA-bind PF00447.17 EMG48850.1 - 1.6e-29 102.4 7.2 5.3e-29 100.7 7.2 2.0 1 0 0 1 1 1 1 HSF-type DNA-binding SUIM_assoc PF16619.5 EMG48850.1 - 0.78 9.9 28.6 0.84 9.7 2.7 5.0 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Oxidored_FMN PF00724.20 EMG48851.1 - 3.5e-68 230.4 0.0 4.6e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 EMG48852.1 - 2.1e-72 244.3 0.0 2.5e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Bac_DNA_binding PF00216.21 EMG48852.1 - 0.072 13.3 0.1 4 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial DNA-binding protein LRR_4 PF12799.7 EMG48853.1 - 0.01 16.2 10.5 0.046 14.2 1.0 4.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EMG48853.1 - 0.77 10.5 7.8 4.4 8.2 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 EMG48853.1 - 1.6 8.6 5.1 0.58 10.0 0.2 3.0 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 EMG48853.1 - 1.9 8.7 4.4 9.5 6.6 0.3 4.3 5 0 0 5 5 5 0 Leucine Rich repeat Elf1 PF05129.13 EMG48854.1 - 7.5e-30 102.8 2.5 9.4e-30 102.5 2.5 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 EMG48854.1 - 0.036 14.2 1.4 0.16 12.1 1.6 2.0 1 1 1 2 2 2 0 Zinc ribbon domain Imm71 PF15602.6 EMG48854.1 - 0.036 14.1 0.1 0.056 13.5 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 71 Ribosomal_L37ae PF01780.19 EMG48854.1 - 0.042 13.9 0.8 0.072 13.2 0.8 1.3 1 1 0 1 1 1 0 Ribosomal L37ae protein family EST1_DNA_bind PF10373.9 EMG48854.1 - 0.043 13.3 0.0 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Pox_A51 PF04948.13 EMG48854.1 - 0.072 11.9 0.8 0.092 11.6 0.8 1.1 1 0 0 1 1 1 0 Poxvirus A51 protein zf-Sec23_Sec24 PF04810.15 EMG48854.1 - 1.6 8.9 5.5 9.5 6.4 0.8 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Caskin1-CID PF16600.5 EMG48855.1 - 0.26 11.9 0.7 0.7 10.5 0.7 1.7 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain NAP PF00956.18 EMG48856.1 - 2.6e-16 59.6 11.5 8.5e-16 57.9 11.5 1.7 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF4849 PF16141.5 EMG48856.1 - 0.0014 17.9 0.5 0.002 17.4 0.1 1.5 2 0 0 2 2 2 1 Putative glycoside hydrolase Family 18, chitinase_18 FOP_dimer PF09398.10 EMG48856.1 - 0.097 12.9 2.9 0.28 11.4 0.4 2.4 2 0 0 2 2 2 0 FOP N terminal dimerisation domain HTH_7 PF02796.15 EMG48857.1 - 1.1e-05 25.5 0.1 0.032 14.3 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 EMG48857.1 - 1.5e-05 25.1 2.4 0.0082 16.4 0.1 2.5 2 0 0 2 2 2 2 Transposase HTH_24 PF13412.6 EMG48857.1 - 2.1e-05 24.0 1.9 0.028 14.0 0.2 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 EMG48857.1 - 9.2e-05 23.0 1.3 0.037 14.6 0.2 2.3 2 0 0 2 2 2 2 Homeodomain-like domain DDRGK PF09756.9 EMG48857.1 - 0.00011 21.9 0.8 0.00016 21.3 0.1 1.5 1 1 0 1 1 1 1 DDRGK domain HTH_23 PF13384.6 EMG48857.1 - 0.0004 20.1 0.4 0.044 13.6 0.1 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_11 PF08279.12 EMG48857.1 - 0.0004 20.3 1.6 0.05 13.5 0.1 2.4 2 0 0 2 2 2 1 HTH domain HTH_17 PF12728.7 EMG48857.1 - 0.0014 18.8 0.5 0.0079 16.4 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 EMG48857.1 - 0.0062 16.4 0.6 0.029 14.3 0.2 2.1 1 1 1 2 2 2 1 ECF sigma factor HTH_38 PF13936.6 EMG48857.1 - 0.0081 15.9 0.3 0.0081 15.9 0.3 2.7 3 1 0 3 3 3 1 Helix-turn-helix domain MarR PF01047.22 EMG48857.1 - 0.0098 15.8 0.3 6 6.9 0.0 2.4 2 0 0 2 2 2 2 MarR family MarR_2 PF12802.7 EMG48857.1 - 0.012 15.5 0.3 0.33 10.9 0.1 2.4 2 0 0 2 2 2 0 MarR family HTH_10 PF04967.12 EMG48857.1 - 0.019 14.7 0.2 0.18 11.7 0.0 2.6 2 1 0 3 3 3 0 HTH DNA binding domain HTH_29 PF13551.6 EMG48857.1 - 0.022 14.8 0.3 0.12 12.5 0.2 2.0 2 0 0 2 2 2 0 Winged helix-turn helix Fe_dep_repress PF01325.19 EMG48857.1 - 0.029 14.6 0.3 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_5 PF01022.20 EMG48857.1 - 0.044 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_WhiA PF02650.14 EMG48857.1 - 0.068 13.5 1.4 1.4 9.3 0.1 2.5 1 1 1 2 2 2 0 WhiA C-terminal HTH domain GntR PF00392.21 EMG48857.1 - 0.14 11.9 0.4 0.36 10.5 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family ATF7IP_BD PF16788.5 EMG48857.1 - 1.7 8.7 12.3 3.9 7.5 12.3 1.5 1 0 0 1 1 1 0 ATF-interacting protein binding domain UCH PF00443.29 EMG48858.1 - 2.8e-46 158.1 0.2 1.3e-45 155.9 0.0 2.3 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EMG48858.1 - 1e-43 147.0 14.1 1.2e-16 60.3 0.3 5.1 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.6 EMG48858.1 - 0.0064 16.1 12.3 0.23 11.0 12.3 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Med31 PF05669.12 EMG48858.1 - 0.043 13.8 0.4 0.74 9.8 0.1 3.2 3 0 0 3 3 3 0 SOH1 Prefoldin PF02996.17 EMG48858.1 - 0.17 11.8 4.7 2.8 7.9 0.8 3.2 3 0 0 3 3 3 0 Prefoldin subunit RcsC PF09456.10 EMG48858.1 - 0.34 10.9 6.4 0.49 10.4 0.4 3.1 3 0 0 3 3 3 0 RcsC Alpha-Beta-Loop (ABL) NPV_P10 PF05531.12 EMG48858.1 - 1.5 9.3 9.2 2.1 8.9 3.5 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein GPS2_interact PF15784.5 EMG48858.1 - 5.9 7.4 6.8 8.4 6.9 0.4 2.8 1 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain BCS1_N PF08740.11 EMG48859.1 - 3.1e-45 154.4 0.0 6.7e-45 153.4 0.0 1.5 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EMG48859.1 - 4.3e-22 78.9 0.0 7.2e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EMG48859.1 - 0.00051 19.3 0.0 0.0008 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EMG48859.1 - 0.00087 19.7 0.0 0.0029 18.0 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EMG48859.1 - 0.0022 18.6 0.0 0.0072 16.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EMG48859.1 - 0.0045 16.8 0.0 0.0079 16.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MetJ PF01340.20 EMG48859.1 - 0.0045 16.9 0.3 0.011 15.7 0.0 1.7 2 0 0 2 2 1 1 Met Apo-repressor, MetJ AAA_33 PF13671.6 EMG48859.1 - 0.0046 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EMG48859.1 - 0.0048 16.4 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 EMG48859.1 - 0.0057 16.7 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EMG48859.1 - 0.0097 16.4 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 EMG48859.1 - 0.012 15.3 0.0 0.045 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMG48859.1 - 0.017 14.8 0.0 0.052 13.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EMG48859.1 - 0.026 14.3 0.1 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 EMG48859.1 - 0.034 14.5 0.0 0.082 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EMG48859.1 - 0.042 13.2 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 EMG48859.1 - 0.056 13.7 0.0 0.18 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMG48859.1 - 0.073 13.0 0.0 0.6 10.0 0.0 2.3 2 1 1 3 3 2 0 Rad17 P-loop domain TsaE PF02367.17 EMG48859.1 - 0.078 13.0 0.0 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 EMG48859.1 - 0.083 13.4 0.0 0.55 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMG48859.1 - 0.099 12.9 0.0 0.21 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EMG48859.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EMG48859.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 EMG48859.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EMG48859.1 - 0.17 12.3 0.0 0.46 10.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain ABC2_membrane PF01061.24 EMG48860.1 - 1.7e-36 125.6 13.5 1.7e-36 125.6 13.5 1.8 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 EMG48860.1 - 4.9e-27 95.1 0.0 9.5e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMG48860.1 - 4.4e-06 26.7 1.7 0.0049 16.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EMG48860.1 - 5.4e-06 25.8 20.3 5.4e-06 25.8 20.3 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EMG48860.1 - 0.0016 17.8 5.4 0.0062 15.9 5.4 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EMG48860.1 - 0.0087 16.0 0.7 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EMG48860.1 - 0.02 14.6 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EMG48860.1 - 0.053 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 EMG48860.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EMG48860.1 - 0.16 12.2 0.6 0.3 11.3 0.6 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EMG48860.1 - 0.17 12.2 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 EMG48861.1 - 1.7e-69 234.1 0.0 2.4e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG48861.1 - 4.2e-32 111.4 0.0 5.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMG48861.1 - 9.2e-06 24.8 1.2 1.2e-05 24.4 1.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EMG48861.1 - 0.0024 17.9 0.1 0.03 14.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EMG48861.1 - 0.023 14.3 0.8 0.039 13.5 0.8 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EMG48861.1 - 0.029 13.7 1.1 0.043 13.2 1.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EMG48861.1 - 0.082 12.5 0.3 0.58 9.7 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2470 PF10615.9 EMG48863.1 - 5.1e-11 43.1 0.0 8.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Voltage_CLC PF00654.20 EMG48864.1 - 6.9e-84 282.1 28.5 1.2e-83 281.3 21.4 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel MT-A70 PF05063.14 EMG48865.1 - 5.4e-12 46.0 0.0 8.8e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 MT-A70 MFS_1 PF07690.16 EMG48866.1 - 2.5e-34 118.8 33.9 2.5e-34 118.8 33.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily CcmD PF04995.14 EMG48866.1 - 2.4 8.3 5.6 9.4 6.4 5.6 2.0 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) MWFE PF15879.5 EMG48867.1 - 0.074 13.2 0.2 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit FA_hydroxylase PF04116.13 EMG48868.1 - 1.1e-23 84.0 22.2 1.1e-23 84.0 22.2 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Iso_dh PF00180.20 EMG48869.1 - 1.1e-73 248.4 0.0 1.3e-73 248.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.8 EMG48869.1 - 0.18 12.0 0.5 0.59 10.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) His_Phos_2 PF00328.22 EMG48870.1 - 3.6e-33 115.5 0.0 4.3e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Fcf1 PF04900.12 EMG48871.1 - 6.2e-37 126.0 0.9 1.1e-36 125.2 0.9 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EMG48871.1 - 0.02 15.2 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 PIN like domain R3H PF01424.22 EMG48872.1 - 6.1e-17 61.4 0.0 1.3e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 EMG48872.1 - 4.8e-06 26.5 10.4 4.8e-06 26.5 10.4 11.6 12 2 1 13 13 13 2 NF-X1 type zinc finger Pkinase PF00069.25 EMG48873.1 - 1.5e-70 237.6 0.6 2.5e-70 236.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG48873.1 - 1.9e-41 142.1 0.0 3.4e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG48873.1 - 5.9e-10 38.9 0.0 1.6e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EMG48873.1 - 0.0036 16.7 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMG48873.1 - 0.006 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EMG48873.1 - 0.0088 15.0 0.4 0.0088 15.0 0.4 2.5 2 0 0 2 2 2 1 Haspin like kinase domain Abhydrolase_1 PF00561.20 EMG48875.1 - 1.5e-41 142.8 0.0 1.7e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMG48875.1 - 0.0049 17.5 0.0 0.0066 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMG48875.1 - 0.099 11.9 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LRR_4 PF12799.7 EMG48876.1 - 3e-08 33.8 10.6 4.1e-06 27.0 2.3 3.6 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG48876.1 - 8.5e-08 31.9 5.1 4.4e-06 26.3 1.0 3.3 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 EMG48876.1 - 0.0017 18.6 8.0 0.47 11.2 0.2 4.0 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 EMG48876.1 - 0.0036 17.2 6.8 5.1 7.4 0.1 4.0 4 0 0 4 4 4 3 Leucine Rich repeat Glyco_transf_28 PF03033.20 EMG48878.1 - 6.9e-33 113.6 0.0 1.7e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 EMG48878.1 - 2.7e-22 78.8 0.0 1.4e-17 63.6 0.0 2.9 2 0 0 2 2 2 2 GRAM domain UDPGT PF00201.18 EMG48878.1 - 1.3e-07 30.8 0.0 2.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 EMG48878.1 - 1.7e-06 28.5 0.4 4.9e-05 23.8 0.4 3.1 1 1 0 1 1 1 1 PH domain PH_2 PF08458.10 EMG48878.1 - 0.0031 17.8 0.1 0.011 16.1 0.1 2.0 1 0 0 1 1 1 1 Plant pleckstrin homology-like region DUF3439 PF11921.8 EMG48878.1 - 0.57 10.2 5.8 2.1 8.3 5.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Fungal_trans PF04082.18 EMG48879.1 - 1.3e-15 57.2 0.9 3e-15 56.0 0.9 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG48879.1 - 1.1e-08 35.1 10.1 1.9e-08 34.3 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3409 PF11889.8 EMG48879.1 - 1.5 8.8 7.9 0.22 11.5 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3409) MCM PF00493.23 EMG48880.1 - 1.6e-102 341.3 0.5 2.4e-102 340.8 0.5 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMG48880.1 - 5.2e-39 133.0 0.8 5.2e-39 133.0 0.8 1.8 2 0 0 2 2 2 1 MCM OB domain MCM6_C PF18263.1 EMG48880.1 - 8.4e-27 93.5 5.6 5.6e-26 90.9 5.6 2.4 1 1 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EMG48880.1 - 2e-26 92.2 0.4 5.3e-26 90.9 0.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMG48880.1 - 6.4e-23 81.3 2.4 1.2e-22 80.5 0.5 2.6 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMG48880.1 - 2.7e-06 26.9 0.0 7.8e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EMG48880.1 - 0.0017 18.3 0.0 0.0093 15.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMG48880.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_6 PF12774.7 EMG48880.1 - 0.033 13.1 0.1 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region GST_N_2 PF13409.6 EMG48881.1 - 1.9e-25 88.9 0.0 6.2e-25 87.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMG48881.1 - 1.7e-11 44.0 0.0 2.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMG48881.1 - 8.9e-05 22.6 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMG48881.1 - 0.00012 22.2 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMG48881.1 - 0.00026 21.3 0.0 0.3 11.5 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain DUF1566 PF07603.11 EMG48881.1 - 0.02 15.3 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) Ras PF00071.22 EMG48882.1 - 2.2e-51 173.7 0.1 3.5e-51 173.0 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG48882.1 - 5.2e-18 65.4 1.9 7.6e-18 64.9 0.0 2.1 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG48882.1 - 1.5e-07 31.0 0.1 2.6e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMG48882.1 - 4.5e-05 23.1 2.6 0.00012 21.7 2.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMG48882.1 - 0.00016 21.8 0.5 0.00045 20.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMG48882.1 - 0.0019 18.1 1.9 1.1 9.2 0.0 2.8 2 1 1 3 3 3 2 RsgA GTPase G-alpha PF00503.20 EMG48882.1 - 0.032 13.4 10.9 0.37 9.9 0.0 3.0 2 1 1 3 3 3 0 G-protein alpha subunit Androgen_recep PF02166.16 EMG48882.1 - 0.31 9.8 11.6 0.39 9.5 11.6 1.1 1 0 0 1 1 1 0 Androgen receptor EIIBC-GUT_N PF03612.14 EMG48882.1 - 0.5 10.1 4.3 0.78 9.5 4.3 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PRC2_HTH_1 PF18118.1 EMG48882.1 - 0.88 10.4 8.4 1.8 9.4 8.4 1.6 1 1 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain 3HCDH_N PF02737.18 EMG48882.1 - 1.7 8.5 4.5 3.4 7.5 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Spt20 PF12090.8 EMG48882.1 - 1.8 8.1 23.5 2.6 7.6 23.5 1.1 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 EMG48882.1 - 2.3 7.2 10.0 3.2 6.7 10.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 EMG48882.1 - 4.2 6.0 11.7 5.6 5.6 11.7 1.1 1 0 0 1 1 1 0 Presenilin ABC_membrane PF00664.23 EMG48883.1 - 6.1e-59 199.9 7.9 8.1e-59 199.5 7.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMG48883.1 - 2.4e-34 118.8 0.1 1.1e-33 116.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_ATPase PF09818.9 EMG48883.1 - 1.5e-06 27.3 0.1 2.6e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SMC_N PF02463.19 EMG48883.1 - 5.2e-05 22.8 2.8 0.003 17.0 2.8 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMG48883.1 - 0.00013 22.3 0.1 0.00099 19.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMG48883.1 - 0.0012 18.5 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 EMG48883.1 - 0.0019 18.2 0.0 0.043 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMG48883.1 - 0.0039 17.6 0.1 0.011 16.1 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EMG48883.1 - 0.0074 16.0 0.4 0.15 11.8 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_7 PF12775.7 EMG48883.1 - 0.0076 15.8 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 EMG48883.1 - 0.019 15.1 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMG48883.1 - 0.022 15.3 0.0 0.067 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMG48883.1 - 0.041 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMG48883.1 - 0.056 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 EMG48883.1 - 0.1 12.4 1.7 0.28 11.0 0.1 2.5 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EMG48883.1 - 0.11 12.9 0.8 3.5 8.1 0.8 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad51 PF08423.11 EMG48884.1 - 7.7e-130 431.7 0.0 9.4e-130 431.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EMG48884.1 - 9.1e-11 41.7 0.0 1.3e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EMG48884.1 - 9.4e-08 31.9 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EMG48884.1 - 4.1e-06 26.3 0.1 1.1e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 EMG48884.1 - 1.2e-05 25.8 0.1 2.9e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DnaB_C PF03796.15 EMG48884.1 - 0.0008 18.8 0.1 0.008 15.5 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain HhH-GPD PF00730.25 EMG48884.1 - 0.046 14.2 0.0 0.2 12.1 0.0 1.9 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein ssDNA_TraI_N PF18272.1 EMG48884.1 - 0.082 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 EMG48884.1 - 0.21 10.7 1.6 0.64 9.1 1.0 1.9 1 1 1 2 2 2 0 PAXNEB protein mRNA_triPase PF02940.15 EMG48885.1 - 3.7e-60 203.4 8.5 5.7e-60 202.7 8.5 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain OPT PF03169.15 EMG48886.1 - 1.1e-164 549.5 43.3 1.3e-164 549.2 43.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein His_Phos_2 PF00328.22 EMG48887.1 - 1.1e-30 107.2 0.0 1.3e-30 107.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) OPT PF03169.15 EMG48888.1 - 3.5e-107 359.6 14.7 3.9e-107 359.4 14.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BofA PF07441.11 EMG48888.1 - 0.09 13.0 11.5 0.058 13.6 7.4 2.7 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA DUF4231 PF14015.6 EMG48888.1 - 0.41 11.1 2.8 18 5.8 1.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF4191 PF13829.6 EMG48888.1 - 1.1 8.5 2.6 3.4 6.9 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) ADH_N PF08240.12 EMG48889.1 - 1.2e-25 89.5 2.5 2e-25 88.8 2.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMG48889.1 - 3.8e-20 72.2 0.0 7.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMG48889.1 - 7e-09 36.8 0.0 1.2e-08 36.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMG48889.1 - 2.3e-08 33.6 0.1 2.3e-08 33.6 0.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EMG48889.1 - 0.00033 20.1 0.1 0.00069 19.0 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EMG48889.1 - 0.0097 15.8 0.7 0.065 13.1 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EMG48889.1 - 0.011 16.3 1.2 0.045 14.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 EMG48889.1 - 0.029 15.0 0.1 0.058 14.0 0.1 1.5 1 0 0 1 1 1 0 PglD N-terminal domain DapB_N PF01113.20 EMG48889.1 - 0.036 14.2 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_7 PF13241.6 EMG48889.1 - 0.049 14.1 0.0 0.087 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.6 EMG48889.1 - 0.061 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.18 EMG48889.1 - 0.15 12.4 0.1 0.69 10.2 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain His_Phos_1 PF00300.22 EMG48890.1 - 1.2e-10 41.4 0.0 6.4e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Hist_deacetyl PF00850.19 EMG48891.1 - 1.5e-88 297.3 0.0 1.9e-88 296.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 EMG48891.1 - 1.2e-33 116.4 0.5 2.1e-33 115.6 0.5 1.4 1 0 0 1 1 1 1 Arb2 domain Pkinase PF00069.25 EMG48892.1 - 1.6e-43 149.0 0.0 2.5e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG48892.1 - 1.5e-25 90.0 0.0 2.1e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMG48892.1 - 0.036 13.0 2.4 0.042 12.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 EMG48892.1 - 0.094 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like ECM11 PF15463.6 EMG48892.1 - 2.8 8.5 5.4 1.5 9.4 0.4 2.8 3 0 0 3 3 3 0 Extracellular mutant protein 11 Methyltr_RsmB-F PF01189.17 EMG48893.1 - 2e-20 73.3 0.0 3.5e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 EMG48893.1 - 0.09 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 NusB family OPT PF03169.15 EMG48894.1 - 3.1e-41 141.7 7.2 3.5e-41 141.5 7.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Mito_carr PF00153.27 EMG48895.1 - 4.5e-48 161.1 4.1 7.4e-20 70.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GCP_N_terminal PF17681.1 EMG48896.1 - 4.4e-39 134.9 3.2 8.3e-39 134.0 3.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EMG48896.1 - 2e-23 83.4 8.9 2e-23 83.4 8.9 2.5 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal Anth_synt_I_N PF04715.13 EMG48896.1 - 0.012 15.8 0.0 0.066 13.4 0.0 2.3 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region Tub PF01167.18 EMG48896.1 - 0.051 13.3 3.7 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 Tub family HBB PF06777.11 EMG48896.1 - 0.13 11.9 2.1 1.4 8.6 0.1 3.0 3 0 0 3 3 3 0 Helical and beta-bridge domain DUF3194 PF11419.8 EMG48896.1 - 0.24 11.8 2.8 3.1 8.2 1.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3194) Aminotran_1_2 PF00155.21 EMG48897.1 - 1.7e-73 247.9 0.0 2.4e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMG48897.1 - 4e-06 25.6 0.0 6.4e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMG48897.1 - 0.00017 20.7 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMG48897.1 - 0.0052 16.2 0.4 0.03 13.6 0.4 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Preseq_ALAS PF09029.10 EMG48897.1 - 0.0062 17.0 0.3 0.012 16.0 0.3 1.5 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence DUF3343 PF11823.8 EMG48897.1 - 0.061 12.8 1.8 0.47 10.0 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3343) GAIN_A PF18619.1 EMG48897.1 - 0.082 13.1 0.2 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A vATP-synt_E PF01991.18 EMG48898.1 - 2.3e-61 206.7 18.4 2.7e-61 206.5 18.4 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Meckelin PF09773.9 EMG48898.1 - 0.086 10.9 2.2 0.12 10.4 2.2 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Folliculin PF11704.8 EMG48898.1 - 1.3 8.9 6.0 0.66 9.8 4.0 1.6 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport FNIP PF05725.12 EMG48899.1 - 0.39 10.9 4.9 9.5 6.5 0.0 4.2 5 1 0 5 5 5 0 FNIP Repeat Trypan_PARP PF05887.11 EMG48900.1 - 8.8 6.3 15.6 22 5.0 15.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ABM PF03992.16 EMG48901.1 - 1e-05 25.5 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.6 EMG48901.1 - 0.0017 18.7 0.1 0.002 18.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) CCDC92 PF14916.6 EMG48902.1 - 0.0045 16.7 1.0 0.0045 16.7 1.0 2.4 2 0 0 2 2 2 1 Coiled-coil domain of unknown function GIT_CC PF16559.5 EMG48902.1 - 0.015 15.2 3.8 0.086 12.7 0.3 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 EMG48902.1 - 0.016 15.6 6.0 1.4 9.4 2.0 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 EMG48902.1 - 0.03 14.4 3.0 2.1 8.5 0.5 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Mto2_bdg PF12808.7 EMG48902.1 - 0.21 11.9 4.9 0.6 10.4 0.6 2.4 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIVA PF05103.13 EMG48902.1 - 0.27 11.3 4.8 1.5 8.9 0.9 2.3 2 0 0 2 2 2 0 DivIVA protein HALZ PF02183.18 EMG48902.1 - 1.3 9.3 9.5 2.3 8.5 3.9 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 EMG48902.1 - 4.5 7.1 7.8 11 5.9 1.5 2.3 2 0 0 2 2 2 0 Septum formation initiator NRBF2 PF08961.10 EMG48902.1 - 5.7 6.5 9.1 13 5.3 0.5 2.8 2 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Asp PF00026.23 EMG48904.1 - 5.5e-06 26.0 0.0 5.8e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Polysacc_deac_1 PF01522.21 EMG48905.1 - 4.5e-25 87.9 0.0 7.7e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EMG48905.1 - 0.0085 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Asp PF00026.23 EMG48906.1 - 1e-22 81.0 1.6 1.2e-22 80.7 1.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMG48906.1 - 6.6e-05 23.2 2.0 0.19 11.9 0.1 2.1 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Apolipoprotein PF01442.18 EMG48907.1 - 0.016 15.1 0.1 0.025 14.5 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Activator-TraM PF11657.8 EMG48907.1 - 0.025 14.4 3.0 2.9 7.7 0.2 2.3 1 1 1 2 2 2 0 Transcriptional activator TraM Vta1 PF04652.16 EMG48907.1 - 0.071 13.1 3.8 0.15 12.0 3.8 1.5 1 0 0 1 1 1 0 Vta1 like YtxH PF12732.7 EMG48907.1 - 0.073 13.6 3.6 0.1 13.1 1.3 2.2 1 1 1 2 2 2 0 YtxH-like protein SOAR PF16533.5 EMG48907.1 - 0.19 11.7 0.9 1.5 8.8 1.7 2.0 2 1 0 2 2 2 0 STIM1 Orai1-activating region CTP_transf_like PF01467.26 EMG48908.1 - 1.6e-32 112.7 0.0 2.7e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Aconitase PF00330.20 EMG48909.1 - 8.9e-161 536.0 0.1 1.1e-160 535.6 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMG48909.1 - 8.9e-43 145.8 0.0 2.1e-42 144.6 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain Cullin PF00888.22 EMG48910.1 - 3.8e-151 504.8 23.6 5.9e-151 504.1 23.6 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EMG48910.1 - 1e-24 86.3 4.2 1e-24 86.3 4.2 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain NAP PF00956.18 EMG48911.1 - 9.3e-92 307.0 17.0 9.3e-92 307.0 17.0 1.8 3 0 0 3 3 3 1 Nucleosome assembly protein (NAP) BSP_II PF05432.11 EMG48911.1 - 0.0008 19.2 12.0 0.0008 19.2 12.0 3.6 3 1 0 3 3 3 1 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.10 EMG48911.1 - 0.0082 16.5 13.8 0.0082 16.5 13.8 3.4 3 0 0 3 3 3 1 Centromere protein B dimerisation domain BUD22 PF09073.10 EMG48911.1 - 4.3 6.6 42.2 6.7e+03 -3.9 42.0 2.1 1 1 0 1 1 1 0 BUD22 Nop14 PF04147.12 EMG48911.1 - 8.2 4.5 42.1 0.13 10.5 12.3 2.3 2 0 0 2 2 2 0 Nop14-like family RXT2_N PF08595.11 EMG48911.1 - 9.9 6.2 32.9 0.12 12.4 4.7 3.7 4 0 0 4 4 4 0 RXT2-like, N-terminal eIF-5_eIF-2B PF01873.17 EMG48912.1 - 0.047 13.6 0.2 0.05 13.5 0.2 1.0 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Ribosomal_S4 PF00163.19 EMG48913.1 - 4.8e-12 46.6 3.2 7.6e-12 46.0 3.2 1.4 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EMG48913.1 - 3.2e-11 42.8 0.0 7.5e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 S4 domain Pox_A_type_inc PF04508.12 EMG48913.1 - 0.79 9.7 2.7 0.86 9.6 0.0 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Ribosomal_L22e PF01776.17 EMG48913.1 - 1.5 9.3 6.0 3.2 8.2 0.8 2.8 3 0 0 3 3 3 0 Ribosomal L22e protein family ABC_membrane_2 PF06472.15 EMG48914.1 - 3.6e-83 279.1 6.3 5.8e-83 278.4 6.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EMG48914.1 - 2.5e-14 54.0 0.1 9e-14 52.2 0.0 2.1 2 1 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 EMG48914.1 - 0.0056 17.2 0.5 0.02 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EMG48914.1 - 0.021 14.6 0.0 9.3 5.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein SMC_N PF02463.19 EMG48914.1 - 0.021 14.3 1.7 5.2 6.4 0.0 2.3 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMG48914.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EMG48914.1 - 0.2 12.0 0.0 1 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RhoGAP PF00620.27 EMG48915.1 - 2.4e-35 121.6 0.1 6.5e-35 120.2 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EMG48915.1 - 4.5e-28 97.2 54.6 2.4e-10 40.5 8.6 4.5 4 0 0 4 4 4 4 LIM domain Candida_ALS_N PF11766.8 EMG48916.1 - 2.1e-89 299.1 4.0 6.8e-89 297.4 4.0 1.9 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Big_8 PF17961.1 EMG48916.1 - 0.0024 18.0 0.0 0.013 15.6 0.0 2.2 1 0 0 1 1 1 1 Bacterial Ig domain DUF1533 PF07550.11 EMG48916.1 - 0.1 12.5 0.1 0.33 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) BolA PF01722.18 EMG48917.1 - 6.9e-17 61.5 0.0 1.3e-16 60.7 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein ADD_DNMT3 PF17980.1 EMG48917.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 HAT_KAT11 PF08214.11 EMG48918.1 - 1e-78 265.1 0.3 1.2e-78 264.9 0.3 1.0 1 0 0 1 1 1 1 Histone acetylation protein SANT_DAMP1_like PF16282.5 EMG48919.1 - 1.4e-17 63.6 5.7 1.1e-15 57.5 0.6 2.7 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EMG48919.1 - 0.00011 22.1 6.7 0.00011 22.1 6.7 4.0 2 2 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 EMG48919.1 - 0.00018 21.6 0.6 0.00064 19.9 0.6 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMG48919.1 - 0.0028 17.8 0.4 0.0081 16.3 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Mem_trans PF03547.18 EMG48919.1 - 0.27 9.6 2.7 0.3 9.4 2.7 1.3 1 0 0 1 1 1 0 Membrane transport protein Zip PF02535.22 EMG48919.1 - 2 7.6 12.8 4.7 6.3 12.8 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EMG48919.1 - 5.8 5.6 21.5 12 4.6 21.5 1.5 1 0 0 1 1 1 0 Presenilin Mus7 PF09462.10 EMG48920.1 - 1.1e-69 236.0 24.2 3.4e-69 234.3 19.2 2.9 2 1 0 2 2 2 1 Mus7/MMS22 family Oxidored_FMN PF00724.20 EMG48921.1 - 8.1e-81 271.9 0.0 1.8e-74 251.1 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.16 EMG48922.1 - 4.8e-31 108.0 45.3 4.9e-30 104.6 20.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMG48922.1 - 6.2e-11 41.8 10.0 2.4e-09 36.5 3.3 2.2 1 1 1 2 2 2 2 MFS_1 like family Ribosomal_L3 PF00297.22 EMG48923.1 - 9.8e-20 70.8 4.7 1.6e-18 66.9 1.7 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 Ribosomal_L6 PF00347.23 EMG48923.1 - 3.7e-15 56.3 2.7 2.3e-06 28.2 0.0 3.0 3 0 0 3 3 3 2 Ribosomal protein L6 CRM1_C PF08767.11 EMG48924.1 - 1.4e-124 415.4 2.4 1.4e-124 415.4 2.4 3.2 4 1 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 EMG48924.1 - 4.2e-38 130.7 6.2 4.2e-38 130.7 6.2 5.3 7 0 0 7 7 7 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EMG48924.1 - 1.1e-33 114.6 2.5 4.7e-33 112.6 2.5 2.2 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EMG48924.1 - 6.2e-29 99.9 4.9 9.8e-29 99.2 1.6 3.3 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 EMG48924.1 - 8.2e-17 60.9 3.4 2.1e-16 59.6 0.7 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 EMG48924.1 - 7.1e-14 51.0 1.2 7.1e-14 51.0 1.2 2.3 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat DALR_1 PF05746.15 EMG48924.1 - 0.00012 22.3 3.1 0.12 12.6 0.1 4.5 4 0 0 4 4 4 1 DALR anticodon binding domain DUF1981 PF09324.10 EMG48924.1 - 0.0078 16.0 0.2 2.2 8.2 0.0 4.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) EDR1 PF14381.6 EMG48924.1 - 0.055 13.2 1.6 0.3 10.8 0.0 3.0 3 1 1 4 4 4 0 Ethylene-responsive protein kinase Le-CTR1 Nitrate_red_del PF02613.15 EMG48924.1 - 0.07 13.1 0.9 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Nitrate reductase delta subunit V-ATPase_H_C PF11698.8 EMG48924.1 - 0.11 12.6 9.2 5.2 7.2 0.2 5.0 4 0 0 4 4 4 0 V-ATPase subunit H DUF4810 PF16068.5 EMG48924.1 - 0.21 12.1 0.7 0.97 10.0 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4810) Ldh_1_C PF02866.18 EMG48925.1 - 7.3e-46 156.2 0.1 1.1e-45 155.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EMG48925.1 - 2.2e-42 144.5 0.1 3.4e-42 143.9 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMG48925.1 - 0.00098 18.2 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EMG48925.1 - 0.11 12.1 0.2 4.2 6.9 0.1 2.8 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase TnpV PF14198.6 EMG48926.1 - 0.0055 16.7 0.2 0.0073 16.3 0.2 1.2 1 0 0 1 1 1 1 Transposon-encoded protein TnpV ArsC PF03960.15 EMG48926.1 - 0.014 15.4 0.1 0.024 14.6 0.1 1.6 1 1 0 1 1 1 0 ArsC family Trehalase PF01204.18 EMG48927.1 - 1.2e-187 624.8 3.3 1.6e-187 624.5 3.3 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EMG48927.1 - 2.9e-17 62.1 0.8 5.8e-17 61.1 0.8 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ran_BP1 PF00638.18 EMG48928.1 - 4.8e-53 178.6 0.9 7.8e-53 177.9 0.9 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EMG48928.1 - 0.00016 21.6 0.4 0.0022 17.9 0.4 2.2 1 1 0 1 1 1 1 WH1 domain Cellulose_synt PF03552.14 EMG48928.1 - 0.0084 14.7 0.9 0.012 14.2 0.9 1.1 1 0 0 1 1 1 1 Cellulose synthase Lig_C PF18330.1 EMG48928.1 - 0.017 15.1 1.3 0.07 13.1 0.0 2.2 2 0 0 2 2 2 0 Ligase Pab1020 C-terminal region polyprenyl_synt PF00348.17 EMG48929.1 - 3.7e-68 229.3 0.0 1e-66 224.6 0.0 2.6 1 1 0 1 1 1 1 Polyprenyl synthetase Ank_2 PF12796.7 EMG48930.1 - 1.1e-31 109.2 1.3 1.4e-09 38.4 0.1 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMG48930.1 - 8e-24 83.7 2.3 2.5e-07 31.1 0.0 5.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMG48930.1 - 6.2e-21 72.3 1.4 0.0003 21.0 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EMG48930.1 - 2.4e-18 65.7 0.4 0.00052 20.3 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EMG48930.1 - 4.3e-17 61.9 0.4 6.4e-05 23.2 0.0 5.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) SPX PF03105.19 EMG48930.1 - 6.7e-17 62.5 24.5 4.6e-08 33.4 4.6 4.3 3 1 2 5 5 5 3 SPX domain GDPD PF03009.17 EMG48930.1 - 0.002 17.9 0.0 0.0077 16.0 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Peptidase_M13_N PF05649.13 EMG48930.1 - 0.18 11.4 4.2 0.31 10.7 0.1 2.2 1 1 1 2 2 2 0 Peptidase family M13 Atypical_Card PF18461.1 EMG48930.1 - 0.31 11.3 2.3 0.32 11.2 0.1 2.2 2 0 0 2 2 2 0 Atypical caspase recruitment domain BCDHK_Adom3 PF10436.9 EMG48931.1 - 2.7e-31 108.6 2.2 6.7e-31 107.3 2.2 1.7 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EMG48931.1 - 4.5e-12 46.5 0.0 1.1e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMG48931.1 - 2.3e-06 27.5 0.0 4.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EMG48931.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain DUF2109 PF09882.9 EMG48931.1 - 0.075 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) DUF2013 PF09431.10 EMG48932.1 - 5.8e-39 133.4 13.6 5.8e-39 133.4 13.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) ANAPC_CDC26 PF10471.9 EMG48932.1 - 4.4 8.2 10.6 0.24 12.2 4.6 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Arginosuc_synth PF00764.19 EMG48933.1 - 8.6e-158 525.7 0.0 9.9e-158 525.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EMG48933.1 - 3.7e-05 23.3 0.0 5.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EMG48933.1 - 0.00044 19.2 0.0 0.00072 18.4 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Cas_Cmr3 PF09700.10 EMG48933.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr3) Asn_synthase PF00733.21 EMG48933.1 - 0.076 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Cupin_8 PF13621.6 EMG48934.1 - 1.1e-12 48.2 0.3 1.8e-12 47.5 0.3 1.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EMG48934.1 - 7.7e-09 36.0 1.3 1.2e-08 35.4 0.2 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase PHD PF00628.29 EMG48934.1 - 8.2e-09 35.2 9.5 1.6e-08 34.3 9.5 1.5 1 0 0 1 1 1 1 PHD-finger JHD PF17811.1 EMG48934.1 - 7.4e-08 32.9 0.1 1.9e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 Jumonji helical domain Cupin_2 PF07883.11 EMG48934.1 - 0.002 17.8 0.0 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 EMG48934.1 - 0.0025 17.3 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Zf_RING PF16744.5 EMG48934.1 - 0.0038 17.3 1.0 0.0085 16.2 1.0 1.6 1 0 0 1 1 1 1 KIAA1045 RING finger Cupin_1 PF00190.22 EMG48934.1 - 0.0074 15.9 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 1 Cupin zf-ZPR1 PF03367.13 EMG48934.1 - 0.026 14.4 0.7 0.056 13.3 0.7 1.5 1 0 0 1 1 1 0 ZPR1 zinc-finger domain zf-HC5HC2H PF13771.6 EMG48934.1 - 0.34 11.2 3.8 1.1 9.5 3.8 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain Peptidase_S8 PF00082.22 EMG48935.1 - 5.2e-39 134.3 16.3 6.5e-27 94.6 2.7 2.7 2 2 0 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.16 EMG48935.1 - 3e-12 47.0 0.2 1.9e-06 28.5 0.0 3.0 3 0 0 3 3 3 2 Peptidase inhibitor I9 Big_2 PF02368.18 EMG48935.1 - 0.042 13.8 2.0 0.33 10.9 0.2 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Glug PF07581.12 EMG48935.1 - 0.077 13.4 1.4 19 5.9 0.2 2.8 2 0 0 2 2 2 0 The GLUG motif ACC_central PF08326.12 EMG48936.1 - 6.7e-264 877.6 0.0 9.8e-264 877.0 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EMG48936.1 - 2.8e-179 596.9 0.0 3.9e-179 596.4 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EMG48936.1 - 3.7e-50 170.3 0.0 7.8e-50 169.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EMG48936.1 - 2.5e-28 98.8 0.1 5.2e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EMG48936.1 - 1.3e-21 76.7 0.0 8.8e-21 74.0 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EMG48936.1 - 1.7e-17 63.0 0.1 3.8e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EMG48936.1 - 0.0012 18.6 0.1 0.86 9.5 0.1 2.7 2 0 0 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EMG48936.1 - 0.002 18.2 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain GxGYxYP_N PF16216.5 EMG48936.1 - 0.013 15.7 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATPgrasp_Ter PF15632.6 EMG48936.1 - 0.043 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 EMG48936.1 - 0.12 11.9 0.0 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Vhr1 PF04001.13 EMG48937.1 - 4.9e-45 151.7 4.9 1e-44 150.7 4.9 1.5 1 0 0 1 1 1 1 Transcription factor Vhr1 Ribonuclease_3 PF00636.26 EMG48937.1 - 0.053 14.1 0.6 0.56 10.8 0.0 2.5 2 1 0 2 2 2 0 Ribonuclease III domain adh_short PF00106.25 EMG48938.1 - 2.3e-40 138.1 0.4 4.5e-40 137.2 0.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG48938.1 - 2.4e-25 89.5 0.1 8.2e-25 87.7 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG48938.1 - 4.4e-05 23.5 0.5 0.0002 21.3 0.5 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMG48938.1 - 0.0087 16.0 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMG48938.1 - 0.014 14.8 0.1 0.023 14.1 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PRKCSH-like PF12999.7 EMG48940.1 - 1.1e-73 246.8 5.4 1.1e-73 246.8 5.4 2.6 3 0 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EMG48940.1 - 6.8e-35 120.0 0.1 6.8e-35 120.0 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF1192 PF06698.11 EMG48940.1 - 0.0064 16.5 0.1 0.032 14.3 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) DUF3107 PF11305.8 EMG48940.1 - 0.074 13.3 1.8 4.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) DUF4570 PF15134.6 EMG48940.1 - 0.084 12.9 17.2 0.26 11.3 5.3 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4570) WWE PF02825.20 EMG48940.1 - 0.093 13.3 0.3 0.45 11.1 0.2 2.2 2 0 0 2 2 2 0 WWE domain ZapB PF06005.12 EMG48940.1 - 0.1 13.1 0.2 0.1 13.1 0.2 4.0 3 1 1 4 4 3 0 Cell division protein ZapB ArsR PF09824.9 EMG48940.1 - 0.12 12.0 7.4 2.2 7.9 0.0 3.2 3 0 0 3 3 3 0 ArsR transcriptional regulator Rit1_C PF17184.4 EMG48940.1 - 0.13 11.7 1.4 0.39 10.1 0.0 2.2 2 1 1 3 3 3 0 Rit1 N-terminal domain HAUS-augmin3 PF14932.6 EMG48940.1 - 0.28 10.7 20.9 0.12 12.0 2.8 3.1 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 NPV_P10 PF05531.12 EMG48940.1 - 0.31 11.5 14.7 0.27 11.7 2.2 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MCD_N PF17408.2 EMG48940.1 - 0.31 11.2 3.0 0.49 10.6 0.6 2.5 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain ArnB_C PF18677.1 EMG48940.1 - 0.63 10.2 6.8 0.75 9.9 2.8 2.5 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain Prefoldin PF02996.17 EMG48940.1 - 0.83 9.6 25.6 0.15 12.0 0.9 4.7 4 1 1 5 5 5 0 Prefoldin subunit Spectrin PF00435.21 EMG48940.1 - 0.99 9.9 17.2 2 9.0 2.5 3.9 3 1 1 4 4 4 0 Spectrin repeat DUF4407 PF14362.6 EMG48940.1 - 1.2 8.4 10.9 1.6 8.0 8.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 EMG48940.1 - 1.3 9.7 19.5 2.6 8.7 0.9 3.7 1 1 1 3 3 3 0 Syntaxin 6, N-terminal YtxH PF12732.7 EMG48940.1 - 1.5 9.4 3.2 57 4.4 1.0 3.1 2 1 0 2 2 2 0 YtxH-like protein ATP-synt_B PF00430.18 EMG48940.1 - 2.1 8.5 8.8 0.54 10.3 3.8 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Syntaxin_2 PF14523.6 EMG48940.1 - 6.8 7.1 25.7 0.82 10.1 4.0 3.9 2 1 2 4 4 4 0 Syntaxin-like protein TssO PF17561.2 EMG48940.1 - 8.5 6.5 20.8 0.087 12.9 6.3 3.2 3 1 0 3 3 3 0 Type VI secretion system, TssO BUD22 PF09073.10 EMG48941.1 - 3e-78 264.1 46.2 4e-78 263.7 46.2 1.2 1 0 0 1 1 1 1 BUD22 TRM13 PF05206.14 EMG48942.1 - 2.8e-74 249.9 2.8 4.8e-72 242.6 2.8 2.1 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 EMG48942.1 - 9.3e-13 47.8 2.0 1.8e-12 46.9 2.0 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 EMG48942.1 - 0.0069 16.4 2.2 0.0092 16.0 0.4 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMG48942.1 - 0.017 14.9 0.2 0.03 14.1 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EMG48942.1 - 0.081 13.7 0.1 0.17 12.6 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain zf-TRAF PF02176.18 EMG48942.1 - 0.082 13.6 0.6 0.082 13.6 0.6 2.0 2 0 0 2 2 2 0 TRAF-type zinc finger Methyltransf_23 PF13489.6 EMG48942.1 - 0.084 12.7 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glycogen_syn PF05693.13 EMG48943.1 - 0 1111.0 0.0 0 1110.8 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 EMG48943.1 - 2.2e-06 27.3 0.0 0.00015 21.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMG48943.1 - 2.8e-06 27.8 0.0 0.0062 17.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EMG48943.1 - 9.6e-06 26.1 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EMG48943.1 - 1.9e-05 24.8 0.1 4.6e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 EMG48943.1 - 0.00023 21.0 0.1 0.00056 19.7 0.1 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain TCTP PF00838.17 EMG48945.1 - 7.3e-72 241.1 1.0 8.2e-72 241.0 1.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Glucan_synthase PF02364.15 EMG48946.1 - 0 1291.6 0.1 0 1291.1 0.1 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EMG48946.1 - 4.8e-36 123.9 4.6 6.2e-35 120.3 4.6 2.5 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TPR_1 PF00515.28 EMG48947.1 - 0.00036 20.2 0.0 0.00066 19.4 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMG48947.1 - 0.0052 16.8 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMG48947.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Trypan_glycop PF00913.19 EMG48947.1 - 0.035 13.4 0.8 0.042 13.1 0.8 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) TPR_16 PF13432.6 EMG48947.1 - 0.058 14.1 0.0 0.087 13.5 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4924 PF16271.5 EMG48947.1 - 0.11 12.5 0.0 2.3 8.2 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4924) UPF0029 PF01205.19 EMG48948.1 - 2.2e-32 111.5 0.0 3.4e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EMG48948.1 - 1.3e-06 28.6 4.0 3.6e-06 27.2 4.0 1.8 1 1 0 1 1 1 1 RWD domain DUF5390 PF17365.2 EMG48948.1 - 0.0083 16.4 0.0 0.76 10.0 0.1 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5390) WD40 PF00400.32 EMG48949.1 - 4.7e-47 157.0 12.4 2.6e-08 34.4 0.1 12.8 13 0 0 13 13 13 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG48949.1 - 9e-31 106.0 0.0 1.4e-05 25.2 0.0 9.0 4 2 5 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EMG48949.1 - 2.9e-20 72.6 0.4 5.1e-20 71.8 0.4 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EMG48949.1 - 2.7e-07 29.9 2.4 0.4 9.6 0.0 6.6 3 2 3 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EMG48949.1 - 4.6e-07 29.5 10.1 0.28 10.5 0.9 5.4 3 1 1 5 5 5 3 WD40-like domain Nucleoporin_N PF08801.11 EMG48949.1 - 9.5e-06 24.6 3.2 1.3 7.7 0.1 5.2 2 1 2 6 6 6 2 Nup133 N terminal like Coatomer_WDAD PF04053.14 EMG48949.1 - 0.00012 21.3 2.2 3.7 6.5 0.0 4.9 4 1 0 5 5 5 1 Coatomer WD associated region Nup160 PF11715.8 EMG48949.1 - 0.00018 20.3 2.3 2.7 6.5 0.1 4.4 2 2 2 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 EMG48949.1 - 0.00044 19.7 0.3 0.89 8.8 0.0 4.2 4 1 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 EMG48949.1 - 0.00067 19.6 0.1 0.0026 17.7 0.1 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat SGL PF08450.12 EMG48949.1 - 0.00068 19.3 0.7 2 8.0 0.1 3.8 3 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Flavoprotein PF02441.19 EMG48950.1 - 6.8e-51 172.1 0.1 1.2e-50 171.3 0.1 1.4 1 0 0 1 1 1 1 Flavoprotein SAM_KSR1 PF13543.6 EMG48950.1 - 0.18 12.0 0.9 17 5.6 0.0 2.5 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 RRN3 PF05327.11 EMG48950.1 - 4.2 5.8 35.0 8.3 4.8 35.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRM PF02005.16 EMG48952.1 - 4.3e-110 368.4 0.4 4.3e-110 368.4 0.4 2.2 2 1 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EMG48952.1 - 0.00016 21.5 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EMG48952.1 - 0.0049 16.5 0.1 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 EMG48952.1 - 0.031 14.0 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.14 EMG48952.1 - 0.1 12.1 0.0 0.36 10.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain MF_alpha_N PF05436.11 EMG48953.1 - 0.012 15.5 1.7 0.013 15.4 1.7 1.1 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Ydc2-catalyt PF09159.10 EMG48954.1 - 1e-33 117.3 0.6 2.1e-32 113.0 0.6 2.1 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 EMG48954.1 - 0.058 13.5 0.4 32 4.6 0.1 3.2 3 0 0 3 3 3 0 Poxvirus A22 protein NLE PF08154.12 EMG48954.1 - 0.07 13.7 0.1 0.28 11.8 0.1 2.1 1 0 0 1 1 1 0 NLE (NUC135) domain Gpr1_Fun34_YaaH PF01184.19 EMG48955.1 - 1.2e-62 211.2 22.0 1.5e-62 210.9 22.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 EMG48956.1 - 1.9e-71 240.0 20.1 2.4e-71 239.6 20.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3589 PF12141.8 EMG48957.1 - 2.8e-80 270.3 2.0 2.7e-48 164.8 0.0 2.5 1 1 1 2 2 2 2 Beta-mannosyltransferases YARHG PF13308.6 EMG48957.1 - 0.1 12.5 0.1 3.9 7.4 0.0 2.7 1 1 1 2 2 2 0 YARHG domain VMA21 PF09446.10 EMG48957.1 - 0.13 12.4 0.7 0.33 11.1 0.7 1.6 1 0 0 1 1 1 0 VMA21-like domain Response_reg PF00072.24 EMG48958.1 - 6.4e-28 97.2 0.4 1.7e-27 95.8 0.4 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EMG48958.1 - 1.5e-25 89.9 0.1 1.5e-20 73.8 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMG48958.1 - 3.5e-14 52.6 0.4 8.5e-14 51.3 0.4 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EMG48958.1 - 0.0012 19.1 0.0 0.23 11.9 0.0 2.6 2 0 0 2 2 2 1 HAMP domain Mid2 PF04478.12 EMG48958.1 - 0.0045 16.8 0.1 0.0045 16.8 0.1 2.2 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Peptidase_S24 PF00717.23 EMG48959.1 - 5.7e-09 35.8 0.0 8.7e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Ten1 PF12658.7 EMG48960.1 - 3.1e-13 49.7 0.0 3.6e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit WD40 PF00400.32 EMG48961.1 - 0.0022 18.8 0.0 0.0022 18.8 0.0 6.5 6 0 0 6 6 6 2 WD domain, G-beta repeat RWD PF05773.22 EMG48961.1 - 0.047 14.0 1.3 0.14 12.5 1.3 1.7 1 0 0 1 1 1 0 RWD domain TRIQK PF15168.6 EMG48961.1 - 0.18 11.7 2.7 0.6 10.0 0.2 2.5 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family DUF1104 PF06518.11 EMG48961.1 - 2.6 8.5 6.8 2.4 8.6 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Fungal_trans PF04082.18 EMG48962.1 - 2.7e-26 92.2 0.5 2.7e-26 92.2 0.5 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG48962.1 - 8.9e-05 22.5 12.6 8.9e-05 22.5 12.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EMG48964.1 - 2.5e-10 40.1 0.1 9.3e-09 35.0 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG48964.1 - 1.8e-06 27.7 0.1 0.061 12.9 0.0 3.1 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG48964.1 - 0.15 12.0 0.0 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 KR domain IMS PF00817.20 EMG48964.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 1 0 1 1 1 0 impB/mucB/samB family AAA PF00004.29 EMG48965.1 - 5.1e-11 43.1 0.1 1.4e-10 41.7 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EMG48965.1 - 2.2e-07 31.0 0.1 2.8e-06 27.4 0.1 2.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EMG48965.1 - 9.3e-06 26.0 0.0 6.3e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMG48965.1 - 0.00016 21.7 0.0 0.0006 19.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMG48965.1 - 0.0011 19.3 0.1 0.017 15.5 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMG48965.1 - 0.0018 18.8 0.1 0.0079 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EMG48965.1 - 0.0074 16.7 0.5 0.29 11.5 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_5 PF07728.14 EMG48965.1 - 0.02 14.9 0.0 0.091 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMG48965.1 - 0.032 14.0 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_6 PF12774.7 EMG48965.1 - 0.046 12.7 0.0 0.15 11.0 0.0 1.9 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_assoc_2 PF16193.5 EMG48965.1 - 0.05 13.9 0.1 0.73 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA C-terminal domain AAA_30 PF13604.6 EMG48965.1 - 0.07 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMG48965.1 - 0.092 12.6 0.0 0.35 10.8 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase MFS_1 PF07690.16 EMG48966.1 - 1.3e-40 139.4 18.9 2.1e-40 138.8 18.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily HEAT PF02985.22 EMG48967.1 - 0.014 15.6 0.0 57 4.4 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.7 EMG48967.1 - 0.045 13.8 0.2 0.045 13.8 0.2 5.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF5082 PF16888.5 EMG48968.1 - 0.0025 18.1 5.9 0.0025 18.1 5.9 3.2 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) Prominin PF05478.11 EMG48968.1 - 0.11 10.4 13.2 0.22 9.4 13.2 1.5 1 0 0 1 1 1 0 Prominin Golgin_A5 PF09787.9 EMG48968.1 - 0.18 11.2 26.0 0.033 13.7 19.5 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF1359 PF07097.11 EMG48968.1 - 0.21 11.8 8.8 0.042 14.1 3.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1359) Styelin PF17562.2 EMG48968.1 - 0.22 11.9 1.3 0.53 10.7 1.3 1.5 1 0 0 1 1 1 0 Styelin NYD-SP28 PF14772.6 EMG48968.1 - 0.24 11.5 19.9 0.036 14.1 9.1 2.6 1 1 0 2 2 2 0 Sperm tail LPP PF04728.13 EMG48968.1 - 0.28 11.6 5.7 39 4.7 3.3 3.7 2 1 1 3 3 3 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 EMG48968.1 - 0.33 11.0 27.4 0.45 10.5 21.5 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZYG-11_interact PF05884.12 EMG48968.1 - 0.44 9.9 1.9 0.86 9.0 1.9 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 Baculo_PEP_C PF04513.12 EMG48968.1 - 0.58 10.2 17.6 0.2 11.7 11.8 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 EMG48968.1 - 1.2 9.4 17.8 3.1 8.2 2.4 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein SlyX PF04102.12 EMG48968.1 - 2.1 9.0 9.1 5.8 7.6 0.0 3.4 2 1 1 3 3 3 0 SlyX Mod_r PF07200.13 EMG48968.1 - 4.8 7.3 32.2 0.035 14.2 20.4 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.12 EMG48968.1 - 7.7 7.1 12.0 2.5 8.6 4.0 3.5 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein CENP-K PF11802.8 EMG48968.1 - 8.4 5.9 28.9 0.45 10.1 21.9 2.2 1 1 2 3 3 3 0 Centromere-associated protein K TRAM_LAG1_CLN8 PF03798.16 EMG48969.1 - 3.5e-36 124.8 24.9 3.5e-36 124.8 24.9 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EMG48969.1 - 9.9e-20 70.0 0.2 9.9e-20 70.0 0.2 2.4 2 0 0 2 2 2 1 TRAM1-like protein FF PF01846.19 EMG48970.1 - 3e-24 84.9 13.4 1.1e-09 38.2 0.3 4.8 4 0 0 4 4 4 3 FF domain WW PF00397.26 EMG48970.1 - 2.9e-17 62.5 18.4 4.7e-09 36.2 6.0 2.8 2 0 0 2 2 2 2 WW domain IgG_binding_B PF01378.17 EMG48970.1 - 0.032 14.3 1.1 0.17 12.0 0.0 2.6 3 0 0 3 3 3 0 B domain CBM_3 PF00942.18 EMG48970.1 - 0.048 14.1 0.2 0.048 14.1 0.2 2.1 2 0 0 2 2 2 0 Cellulose binding domain Glyco_hyd_101C PF17451.2 EMG48970.1 - 0.99 9.7 14.0 0.97 9.7 1.9 2.9 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain ARPC4 PF05856.12 EMG48971.1 - 1.5e-76 255.7 7.0 1.8e-76 255.4 7.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) VHS PF00790.19 EMG48972.1 - 8.1e-33 113.2 0.5 8.1e-33 113.2 0.5 1.8 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 EMG48972.1 - 3.4e-14 52.2 0.0 6.8e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMG48972.1 - 6.1e-13 48.2 0.0 1.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EMG48972.1 - 1.1e-11 44.4 0.5 2e-11 43.5 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.14 EMG48972.1 - 1.9e-06 28.1 4.5 7.8e-06 26.1 3.6 2.5 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 EMG48972.1 - 0.00059 19.6 1.4 0.0013 18.5 1.4 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif MFS_1 PF07690.16 EMG48973.1 - 5.7e-35 120.9 17.7 8.9e-35 120.2 17.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SDA1 PF05285.12 EMG48974.1 - 0.054 12.9 19.9 0.11 11.9 19.9 1.5 1 0 0 1 1 1 0 SDA1 PI3K_1B_p101 PF10486.9 EMG48974.1 - 3.5 5.3 9.0 7.3 4.2 9.0 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SRP54 PF00448.22 EMG48975.1 - 6.5e-78 260.9 1.0 1.9e-77 259.4 0.5 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EMG48975.1 - 1.4e-28 99.4 4.4 1.4e-28 99.4 4.4 3.6 2 1 0 2 2 1 1 Signal peptide binding domain SRP54_N PF02881.19 EMG48975.1 - 5.2e-17 61.8 1.6 1.2e-16 60.6 1.6 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EMG48975.1 - 4.1e-06 26.5 1.7 0.0042 16.7 0.7 3.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EMG48975.1 - 0.00016 21.9 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EMG48975.1 - 0.00019 21.5 0.0 0.0011 19.1 0.0 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 EMG48975.1 - 0.0024 17.8 0.0 0.0076 16.1 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 EMG48975.1 - 0.0025 16.8 0.3 0.016 14.2 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EMG48975.1 - 0.0081 15.9 0.0 0.029 14.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain XPC-binding PF09280.11 EMG48975.1 - 0.016 14.9 28.1 0.18 11.6 3.3 3.6 2 1 1 3 3 3 0 XPC-binding domain MipZ PF09140.11 EMG48975.1 - 0.016 14.5 0.0 5.7 6.2 0.0 2.3 2 0 0 2 2 2 0 ATPase MipZ CRAL_TRIO PF00650.20 EMG48975.1 - 0.017 14.9 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 CRAL/TRIO domain AAA_31 PF13614.6 EMG48975.1 - 0.019 14.9 1.1 0.12 12.3 0.1 2.5 1 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EMG48975.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SRPRB PF09439.10 EMG48975.1 - 0.024 14.1 0.3 15 5.0 0.0 3.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 EMG48975.1 - 0.026 15.1 0.1 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EMG48975.1 - 0.066 13.0 0.7 0.21 11.3 0.1 2.2 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EMG48975.1 - 0.073 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EMG48975.1 - 0.077 12.9 0.8 0.45 10.4 0.1 2.3 2 0 0 2 2 2 0 NTPase Arf PF00025.21 EMG48975.1 - 0.077 12.4 0.1 0.76 9.2 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_28 PF13521.6 EMG48975.1 - 0.089 13.0 0.0 0.56 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EMG48975.1 - 0.092 12.0 2.5 0.21 10.8 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_17 PF13207.6 EMG48975.1 - 0.12 12.8 0.3 0.12 12.8 0.3 3.1 3 1 0 3 3 2 0 AAA domain AAA PF00004.29 EMG48975.1 - 0.24 11.8 1.8 3 8.3 0.4 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) STI1 PF17830.1 EMG48975.1 - 4.8 7.2 46.1 0.36 10.8 8.3 4.1 5 0 0 5 5 4 0 STI1 domain TFIIA PF03153.13 EMG48975.1 - 8.9 6.2 11.6 18 5.2 11.6 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIID_30kDa PF03540.13 EMG48976.1 - 1e-25 89.4 0.1 1.9e-25 88.5 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 EMG48976.1 - 0.0089 16.6 3.1 0.0089 16.6 3.1 2.0 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Bromo_TP PF07524.13 EMG48976.1 - 0.0097 15.9 0.3 7.3 6.7 0.0 2.6 3 0 0 3 3 3 2 Bromodomain associated DUF4114 PF13448.6 EMG48976.1 - 0.018 15.8 0.4 0.018 15.8 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4114) Pribosyl_synth PF14572.6 EMG48976.1 - 0.1 12.6 0.2 0.21 11.6 0.1 1.5 1 1 0 1 1 1 0 Phosphoribosyl synthetase-associated domain TAF4 PF05236.14 EMG48976.1 - 0.28 10.9 0.0 0.28 10.9 0.0 2.3 2 1 1 3 3 3 0 Transcription initiation factor TFIID component TAF4 family Pex14_N PF04695.13 EMG48976.1 - 1.4 9.5 8.1 1.2 9.8 1.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Shisa PF13908.6 EMG48976.1 - 4.3 7.5 8.7 3.1 8.0 1.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator HECT PF00632.25 EMG48977.1 - 4.7e-74 249.6 0.1 1e-73 248.5 0.1 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) F-actin_cap_A PF01267.17 EMG48978.1 - 2.7e-67 227.0 1.9 3.1e-67 226.8 1.9 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit TPR_2 PF07719.17 EMG48979.1 - 9.4e-35 115.9 10.8 8.1e-07 28.7 0.0 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 EMG48979.1 - 5.8e-32 108.2 21.6 2.1e-07 30.5 0.1 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 EMG48979.1 - 4.7e-25 85.7 13.7 6.2e-06 26.0 0.0 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG48979.1 - 8.4e-23 80.4 19.4 7.4e-18 64.5 1.1 5.0 4 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EMG48979.1 - 7.7e-22 76.7 7.0 0.01 15.5 0.1 8.7 5 1 4 9 9 9 6 TPR repeat TPR_12 PF13424.6 EMG48979.1 - 1.3e-16 60.6 5.4 0.0048 17.1 0.0 6.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EMG48979.1 - 3.9e-14 53.0 0.0 0.00024 21.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMG48979.1 - 9.9e-14 50.7 9.4 0.13 12.7 0.6 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 EMG48979.1 - 3.3e-10 39.9 2.8 0.016 15.8 0.0 7.1 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMG48979.1 - 3.4e-08 33.6 0.0 0.64 11.0 0.0 5.0 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EMG48979.1 - 8.6e-08 32.2 0.0 0.004 17.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMG48979.1 - 4.8e-07 30.2 0.9 0.19 12.3 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMG48979.1 - 4.1e-06 26.4 0.7 7.2 6.9 0.0 6.6 6 1 1 7 7 7 1 Tetratricopeptide repeat PH PF00169.29 EMG48980.1 - 5.2e-16 59.1 0.0 1.8e-15 57.3 0.0 2.0 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 EMG48980.1 - 2.3e-10 40.2 0.0 5.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMG48980.1 - 4.7e-09 35.7 0.1 1.3e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SAM_2 PF07647.17 EMG48980.1 - 2.3e-06 27.6 0.0 4.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 EMG48980.1 - 0.00034 21.0 0.3 0.00034 21.0 0.3 4.0 3 2 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 EMG48980.1 - 0.00065 19.9 0.0 0.028 14.7 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.17 EMG48980.1 - 0.003 17.2 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 EMG48980.1 - 0.0097 16.3 0.0 0.02 15.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MFS_1 PF07690.16 EMG48981.1 - 1.7e-14 53.6 41.0 5.1e-13 48.7 39.1 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMG48981.1 - 1.4e-09 37.0 24.6 1.8e-09 36.6 24.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SHR3_chaperone PF08229.11 EMG48981.1 - 0.034 13.1 3.6 0.027 13.4 0.6 2.3 2 0 0 2 2 2 0 ER membrane protein SH3 CRPA PF05745.11 EMG48981.1 - 0.046 13.7 0.3 0.23 11.5 0.3 2.2 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) EMP70 PF02990.16 EMG48982.1 - 1.6e-144 482.4 18.3 2e-144 482.1 18.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 SNAP PF14938.6 EMG48983.1 - 4.8e-106 354.3 4.7 5.4e-106 354.1 4.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 EMG48983.1 - 4.3e-06 26.4 6.5 0.33 11.2 0.4 5.0 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMG48983.1 - 5.6e-06 26.0 6.8 0.76 9.7 0.3 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMG48983.1 - 1e-05 25.2 1.4 0.02 14.9 0.1 3.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMG48983.1 - 1e-05 25.7 7.6 0.0015 18.8 0.5 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMG48983.1 - 0.00085 19.4 10.5 0.2 12.0 0.1 4.1 5 0 0 5 5 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG48983.1 - 0.0015 18.7 3.5 0.33 11.2 0.1 3.7 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EMG48983.1 - 0.002 18.6 2.5 3.5 8.5 0.4 4.2 3 2 2 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMG48983.1 - 0.014 16.2 0.4 29 5.8 0.0 4.2 1 1 3 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 EMG48983.1 - 0.027 14.2 0.8 0.3 10.8 0.4 2.8 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_MalT PF17874.1 EMG48983.1 - 0.036 13.4 0.0 0.093 12.1 0.0 1.6 1 1 0 1 1 1 0 MalT-like TPR region NSF PF02071.20 EMG48983.1 - 0.048 14.4 19.7 0.29 12.0 0.2 6.3 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat DUF535 PF04393.13 EMG48983.1 - 0.096 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF535) Foie-gras_1 PF11817.8 EMG48983.1 - 0.1 12.1 0.2 0.16 11.5 0.2 1.3 1 1 0 1 1 1 0 Foie gras liver health family 1 TOM20_plant PF06552.12 EMG48983.1 - 0.17 11.6 2.2 0.24 11.1 0.3 1.9 1 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_16 PF13432.6 EMG48983.1 - 0.31 11.7 3.8 0.95 10.2 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMG48983.1 - 0.9 9.5 5.1 13 5.8 0.1 4.0 3 2 2 5 5 5 0 Tetratricopeptide repeat DUF2225 PF09986.9 EMG48983.1 - 1.2 8.8 5.8 2.1 8.0 0.2 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_11 PF13414.6 EMG48983.1 - 4.7 7.0 10.5 29 4.4 0.1 4.0 4 0 0 4 4 4 0 TPR repeat MIT PF04212.18 EMG48983.1 - 5.5 7.1 10.6 14 5.8 0.3 4.0 3 2 1 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3464 PF11947.8 EMG48984.1 - 0.12 12.1 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 ATP-synt PF00231.19 EMG48985.1 - 4e-77 259.7 8.1 4.7e-77 259.5 8.1 1.0 1 0 0 1 1 1 1 ATP synthase NDUFB10 PF10249.9 EMG48986.1 - 0.0039 17.7 0.5 0.0047 17.4 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Frag1 PF10277.9 EMG48987.1 - 3.1e-38 131.5 13.9 3.1e-38 131.5 13.9 3.1 3 1 1 4 4 4 1 Frag1/DRAM/Sfk1 family FTR1 PF03239.14 EMG48988.1 - 2.3e-72 243.8 5.6 3e-49 167.9 2.4 2.1 2 0 0 2 2 2 2 Iron permease FTR1 family MARCKS PF02063.17 EMG48988.1 - 0.026 14.5 1.6 0.04 13.9 1.6 1.2 1 0 0 1 1 1 0 MARCKS family Romo1 PF10247.9 EMG48988.1 - 0.76 10.2 3.4 0.49 10.8 0.3 2.4 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Orf78 PF06024.12 EMG48988.1 - 1.8 8.9 0.0 1.8 8.9 0.0 3.3 4 1 0 4 4 4 0 Orf78 (ac78) E1_DerP2_DerF2 PF02221.15 EMG48989.1 - 5.7e-27 94.8 0.4 7.1e-27 94.5 0.4 1.1 1 0 0 1 1 1 1 ML domain Nnf1 PF03980.14 EMG48990.1 - 4.5e-24 84.9 1.5 9.1e-24 84.0 1.5 1.5 1 0 0 1 1 1 1 Nnf1 HALZ PF02183.18 EMG48990.1 - 0.016 15.4 2.2 0.058 13.6 2.2 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper HetR_C PF18460.1 EMG48990.1 - 0.038 13.9 0.5 0.082 12.8 0.0 1.7 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain DegS PF05384.11 EMG48990.1 - 0.082 12.4 4.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Sensor protein DegS Ribosomal_S15 PF00312.22 EMG48991.1 - 5.2e-23 81.1 0.8 5.2e-23 81.1 0.8 3.0 3 0 0 3 3 3 1 Ribosomal protein S15 DUF1993 PF09351.10 EMG48991.1 - 0.51 10.5 5.1 1.8 8.7 2.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) DUF836 PF05768.14 EMG48992.1 - 0.076 13.4 0.1 0.68 10.4 0.0 2.6 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) DUF5344 PF17279.2 EMG48992.1 - 0.84 10.3 3.9 10 6.8 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5344) GrpE PF01025.19 EMG48993.1 - 1e-48 165.2 7.7 2e-48 164.2 7.7 1.5 1 1 0 1 1 1 1 GrpE DUF4201 PF13870.6 EMG48993.1 - 0.1 12.3 8.6 0.066 12.9 7.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF5561 PF17716.1 EMG48993.1 - 0.2 10.9 2.6 0.29 10.4 2.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5561) DUF4298 PF14131.6 EMG48993.1 - 0.26 11.3 2.9 0.32 11.0 1.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) DUF2408 PF10303.9 EMG48993.1 - 0.28 11.7 5.0 0.44 11.1 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4407 PF14362.6 EMG48993.1 - 0.33 10.3 5.1 0.42 9.9 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2205 PF10224.9 EMG48993.1 - 0.47 10.5 6.1 0.077 13.0 0.8 2.2 1 1 1 2 2 2 0 Short coiled-coil protein V_ATPase_I PF01496.19 EMG48993.1 - 0.59 8.0 3.7 0.67 7.8 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 EMG48993.1 - 0.62 10.4 11.4 0.92 9.8 11.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GCN5L1 PF06320.13 EMG48993.1 - 1 9.5 10.2 2.6 8.2 9.1 1.9 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Prominin PF05478.11 EMG48993.1 - 1.4 6.8 3.5 1.6 6.5 3.5 1.1 1 0 0 1 1 1 0 Prominin LMBR1 PF04791.16 EMG48993.1 - 2.6 6.9 3.1 3.1 6.6 3.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HSP70 PF00012.20 EMG48993.1 - 4 5.5 9.9 5.3 5.1 9.9 1.1 1 0 0 1 1 1 0 Hsp70 protein Iso_dh PF00180.20 EMG48994.1 - 3.6e-105 351.9 0.1 6.5e-105 351.1 0.1 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Transposase_24 PF03004.14 EMG48994.1 - 0.21 11.7 0.7 0.45 10.6 0.7 1.5 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) WD40 PF00400.32 EMG48995.1 - 6.5e-09 36.3 3.9 0.22 12.5 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG48995.1 - 0.0057 16.9 0.1 4.1 7.8 0.1 3.2 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-bind_7 PF15963.5 EMG48996.1 - 5e-29 100.0 5.0 1.5e-28 98.5 1.0 2.9 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EMG48996.1 - 8.5e-10 38.7 0.0 2e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMG48996.1 - 0.0038 17.5 0.3 0.02 15.1 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain K_oxygenase PF13434.6 EMG48996.1 - 0.011 14.9 1.9 0.033 13.3 0.4 2.2 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) SANT_DAMP1_like PF16282.5 EMG48996.1 - 0.04 14.1 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 PIG-H PF10181.9 EMG48997.1 - 7e-24 83.5 0.1 1.3e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Sulfate_transp PF00916.20 EMG48999.1 - 1.6e-71 241.1 20.0 1.6e-71 241.1 20.0 1.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 EMG48999.1 - 2.8e-13 49.5 0.5 2e-11 43.6 0.2 2.5 2 0 0 2 2 2 2 STAS domain cNMP_binding PF00027.29 EMG48999.1 - 0.00057 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CPSase_L_D2 PF02786.17 EMG49000.1 - 3.9e-111 369.6 0.1 7.1e-85 283.8 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EMG49000.1 - 1.1e-39 135.6 0.1 3e-39 134.1 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EMG49000.1 - 1.1e-20 73.9 0.0 5.1e-09 35.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EMG49000.1 - 1.5e-18 67.1 0.3 3.2e-08 33.4 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EMG49000.1 - 2.6e-11 43.4 0.0 0.00011 21.9 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 EMG49000.1 - 3.3e-07 30.1 0.2 0.007 16.0 0.1 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 EMG49000.1 - 5.1e-05 22.8 0.2 0.1 12.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EMG49000.1 - 8.4e-05 22.4 0.3 0.057 13.2 0.1 2.9 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.6 EMG49000.1 - 0.011 15.4 0.0 0.088 12.4 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain TrkA_N PF02254.18 EMG49000.1 - 0.015 15.5 0.3 0.093 13.0 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain Epimerase PF01370.21 EMG49000.1 - 0.075 12.5 0.0 0.28 10.6 0.0 2.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 EMG49001.1 - 6.9e-14 51.5 12.6 3.6e-12 45.9 12.6 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 EMG49001.1 - 0.0004 18.9 0.0 0.0005 18.6 0.0 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Gly-zipper_Omp PF13488.6 EMG49001.1 - 0.56 10.2 2.6 0.48 10.5 0.2 2.1 2 0 0 2 2 2 0 Glycine zipper Candida_ALS_N PF11766.8 EMG49002.1 - 1.5e-82 276.6 0.8 1.7e-82 276.4 0.8 1.1 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding MFS_1 PF07690.16 EMG49003.1 - 3.7e-24 85.3 6.6 4.3e-24 85.1 6.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG49003.1 - 4.3e-07 29.2 1.3 4.3e-07 29.2 1.3 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMG49003.1 - 3.2e-05 22.6 2.4 4.3e-05 22.1 2.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EMG49003.1 - 0.00098 17.6 1.6 0.0012 17.3 1.6 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector DUF3792 PF12670.7 EMG49003.1 - 0.027 14.6 1.7 0.027 14.6 1.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) SSXRD PF09514.10 EMG49004.1 - 0.015 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 SSXRD motif DUF2207 PF09972.9 EMG49004.1 - 0.93 8.2 4.0 0.92 8.2 4.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sec61_beta PF03911.16 EMG49005.1 - 3e-18 65.6 1.1 3.9e-18 65.2 1.1 1.2 1 0 0 1 1 1 1 Sec61beta family Podoplanin PF05808.11 EMG49005.1 - 0.023 14.8 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Podoplanin tRNA-synt_2b PF00587.25 EMG49006.1 - 1.9e-30 106.2 0.0 3.9e-30 105.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EMG49006.1 - 6.3e-05 23.1 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Apolipoprotein PF01442.18 EMG49007.1 - 6.7e-05 22.8 16.8 0.03 14.2 9.1 2.6 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EMG49007.1 - 0.032 14.8 37.5 1.7 9.2 5.0 5.2 3 2 0 4 4 4 0 YtxH-like protein RAB3GAP2_N PF14655.6 EMG49007.1 - 0.065 12.5 7.5 0.0088 15.3 3.4 1.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF883 PF05957.13 EMG49007.1 - 0.56 10.9 18.5 4.3 8.0 1.4 5.0 2 2 4 6 6 6 0 Bacterial protein of unknown function (DUF883) DUF4398 PF14346.6 EMG49007.1 - 2.6 8.7 7.6 10 6.8 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4398) Prominin PF05478.11 EMG49007.1 - 2.8 5.8 17.5 0.2 9.5 2.9 2.6 2 1 0 2 2 2 0 Prominin RRM_1 PF00076.22 EMG49008.1 - 4.4e-06 26.4 0.1 9.2e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.18 EMG49009.1 - 9.4e-71 237.2 0.7 1.6e-70 236.4 0.7 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EMG49009.1 - 2.1e-20 72.0 5.6 5.1e-20 70.8 5.6 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EMG49009.1 - 0.037 14.5 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-met PF12874.7 EMG49009.1 - 0.056 13.9 0.9 0.17 12.3 0.9 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type PP2C PF00481.21 EMG49010.1 - 2.2e-73 247.1 0.2 3.9e-70 236.4 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Candida_ALS_N PF11766.8 EMG49011.1 - 6.8e-78 261.4 0.0 8.2e-78 261.1 0.0 1.1 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding PTH2 PF01981.16 EMG49012.1 - 6.2e-43 145.8 0.0 1.5e-42 144.6 0.0 1.7 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DnaJ PF00226.31 EMG49012.1 - 1.2e-09 38.2 0.2 1.2e-09 38.2 0.2 2.0 2 0 0 2 2 2 1 DnaJ domain EOS1 PF12326.8 EMG49012.1 - 0.19 11.6 0.6 0.29 11.0 0.6 1.3 1 0 0 1 1 1 0 N-glycosylation protein SRP19 PF01922.17 EMG49013.1 - 3.2e-29 101.7 0.0 5.8e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Pribosyltran PF00156.27 EMG49014.1 - 1.8e-16 60.1 0.0 2.6e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PA PF02225.22 EMG49014.1 - 0.063 13.3 0.1 0.11 12.5 0.1 1.4 1 1 0 1 1 1 0 PA domain E1-E2_ATPase PF00122.20 EMG49015.1 - 8.1e-41 139.5 1.0 3.2e-40 137.6 0.2 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMG49015.1 - 1.1e-30 106.7 9.2 1.1e-30 106.7 9.2 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMG49015.1 - 3.2e-20 73.3 0.0 1.9e-15 57.8 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMG49015.1 - 1.9e-11 43.9 0.0 4.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EMG49015.1 - 1.3e-10 40.8 0.0 4e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2157 PF09925.9 EMG49015.1 - 0.0012 18.7 4.0 0.42 10.4 0.0 3.6 4 0 0 4 4 4 2 Predicted membrane protein (DUF2157) Hydrolase_3 PF08282.12 EMG49015.1 - 0.0056 16.5 0.2 0.0056 16.5 0.2 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PASTA PF03793.19 EMG49015.1 - 0.0085 15.9 0.0 4 7.4 0.0 2.7 2 0 0 2 2 2 2 PASTA domain DUF2207 PF09972.9 EMG49015.1 - 0.19 10.5 0.0 0.19 10.5 0.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 EMG49015.1 - 0.7 9.5 2.7 14 5.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Meth_synt_2 PF01717.18 EMG49016.1 - 5e-152 505.8 0.0 1.5e-146 487.8 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EMG49016.1 - 4.7e-120 400.8 0.0 4e-114 381.3 0.1 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain DUF3502 PF12010.8 EMG49016.1 - 0.0081 16.8 0.4 0.79 10.4 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3502) Apolipoprotein PF01442.18 EMG49016.1 - 0.1 12.4 0.3 0.26 11.1 0.3 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain SEP PF08059.13 EMG49017.1 - 1.8e-23 82.9 0.1 9.7e-23 80.5 0.0 2.3 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 EMG49017.1 - 4.7e-16 58.8 0.0 1e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EMG49017.1 - 3.4e-09 36.4 0.5 5.9e-09 35.6 0.5 1.4 1 0 0 1 1 1 1 UBA-like domain GET2 PF08690.10 EMG49017.1 - 0.27 10.9 4.8 0.48 10.1 4.8 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 RNB PF00773.19 EMG49018.1 - 0.00013 21.5 0.0 0.19 11.0 0.0 2.4 2 0 0 2 2 2 2 RNB domain Chorismate_bind PF00425.18 EMG49019.1 - 2.4e-91 305.9 0.0 3.7e-91 305.3 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EMG49019.1 - 4.7e-31 107.9 0.0 1.3e-28 100.0 0.0 3.0 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region DUF2312 PF10073.9 EMG49019.1 - 0.07 12.8 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Myb_DNA-bind_6 PF13921.6 EMG49020.1 - 2.7e-12 46.7 1.6 5.1e-11 42.7 0.2 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMG49020.1 - 2e-10 40.7 2.7 1.6e-08 34.6 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Ras PF00071.22 EMG49021.1 - 4e-64 215.1 0.2 4.7e-64 214.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG49021.1 - 4.5e-37 126.9 0.1 7.2e-37 126.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG49021.1 - 8.2e-16 57.9 0.1 9.5e-16 57.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMG49021.1 - 1.5e-07 31.0 0.1 1.9e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EMG49021.1 - 6.6e-07 29.1 0.1 1.9e-06 27.6 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EMG49021.1 - 2.7e-05 23.7 0.0 4.2e-05 23.1 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EMG49021.1 - 3.4e-05 23.8 0.8 0.15 11.9 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMG49021.1 - 3.6e-05 23.8 0.0 7.1e-05 22.9 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMG49021.1 - 0.00021 20.8 0.0 0.00089 18.8 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 EMG49021.1 - 0.0042 17.4 0.1 0.15 12.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 EMG49021.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 EMG49021.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Septin PF00735.18 EMG49021.1 - 0.014 14.7 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Septin CENP-M PF11111.8 EMG49021.1 - 0.04 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_24 PF13479.6 EMG49021.1 - 0.053 13.2 0.2 0.22 11.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 EMG49021.1 - 0.058 13.8 0.0 0.088 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EMG49021.1 - 0.15 12.6 1.6 0.43 11.1 1.2 2.0 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EMG49021.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ETC_C1_NDUFA5 PF04716.14 EMG49022.1 - 1.2e-27 95.5 0.1 1.8e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region WW PF00397.26 EMG49022.1 - 4.4e-10 39.5 0.4 1.4e-09 37.9 0.4 1.9 1 0 0 1 1 1 1 WW domain Pro-rich PF15240.6 EMG49022.1 - 0.022 15.1 37.8 0.033 14.5 37.8 1.3 1 0 0 1 1 1 0 Proline-rich PXA PF02194.15 EMG49023.1 - 4.1e-41 140.9 3.2 1.5e-40 139.1 3.2 2.1 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EMG49023.1 - 2.3e-22 79.7 0.6 2.2e-21 76.5 0.0 3.0 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 EMG49023.1 - 4.8e-20 71.6 2.8 4.8e-20 71.6 2.8 2.8 2 0 0 2 2 2 1 PX domain RGS PF00615.19 EMG49023.1 - 3.6e-08 33.7 0.9 3.6e-08 33.7 0.9 4.7 4 2 0 4 4 4 1 Regulator of G protein signaling domain G-patch PF01585.23 EMG49024.1 - 0.00062 19.6 0.9 0.003 17.4 0.9 2.2 1 1 0 1 1 1 1 G-patch domain CLN3 PF02487.17 EMG49024.1 - 0.0067 15.5 5.8 0.01 14.9 5.8 1.4 1 1 0 1 1 1 1 CLN3 protein G-patch_2 PF12656.7 EMG49024.1 - 0.038 14.1 0.2 0.038 14.1 0.2 4.2 2 1 0 2 2 2 0 G-patch domain XRN_M PF17846.1 EMG49024.1 - 4 6.3 22.9 4.8 6.0 22.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF2151 PF10221.9 EMG49024.1 - 9.7 4.6 35.1 14 4.2 35.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator RRM_1 PF00076.22 EMG49025.1 - 1.5e-33 114.5 8.9 7.7e-15 54.5 0.1 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMG49025.1 - 2.1e-09 37.1 0.1 0.00021 21.1 0.0 4.8 4 1 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EMG49025.1 - 0.0047 16.5 0.1 0.028 14.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMT2_N PF17987.1 EMG49025.1 - 0.01 16.0 0.1 0.058 13.6 0.1 2.4 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal DUF1438 PF07270.11 EMG49025.1 - 0.026 14.6 0.7 0.15 12.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) RRM_3 PF08777.11 EMG49025.1 - 0.04 14.0 2.8 10 6.2 0.0 3.4 2 1 2 4 4 4 0 RNA binding motif BRAP2 PF07576.12 EMG49025.1 - 0.063 13.5 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 BRCA1-associated protein 2 Nup35_RRM_2 PF14605.6 EMG49025.1 - 0.074 13.1 0.0 22 5.1 0.0 3.8 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.6 EMG49025.1 - 0.094 13.6 0.0 26 6.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMG49025.1 - 0.15 12.6 0.0 1.6 9.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_1 PF00133.22 EMG49026.1 - 1.9e-42 145.3 0.1 1.2e-32 112.9 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EMG49026.1 - 9.6e-17 60.8 0.2 3.8e-09 35.8 0.0 3.4 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EMG49026.1 - 5.7e-14 52.3 0.1 3e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EMG49026.1 - 1.5e-06 27.8 0.0 3.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Tyr_Deacylase PF02580.16 EMG49026.1 - 0.054 14.0 0.2 0.44 11.1 0.0 2.2 2 0 0 2 2 2 0 D-Tyr-tRNA(Tyr) deacylase WD40 PF00400.32 EMG49027.1 - 3.2e-41 138.5 26.6 2.4e-07 31.3 0.2 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat CDC4_D PF16856.5 EMG49027.1 - 8e-22 76.9 6.6 1.5e-21 76.0 6.6 1.5 1 0 0 1 1 1 1 Cell division control protein 4 dimerisation domain F-box-like PF12937.7 EMG49027.1 - 1.8e-11 43.8 0.1 3.8e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMG49027.1 - 6.7e-11 41.8 0.5 1.3e-10 40.9 0.5 1.5 1 0 0 1 1 1 1 F-box domain PALB2_WD40 PF16756.5 EMG49027.1 - 1.1e-05 24.5 1.0 0.073 12.0 0.0 3.8 2 2 2 4 4 4 2 Partner and localizer of BRCA2 WD40 domain ANAPC4_WD40 PF12894.7 EMG49027.1 - 2e-05 24.8 0.7 1.2 9.5 0.0 5.2 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMG49027.1 - 0.00033 19.4 1.0 0.16 10.6 0.1 3.5 3 1 0 3 3 3 1 Nucleoporin Nup120/160 F-box_4 PF15966.5 EMG49027.1 - 0.00096 19.0 0.5 0.0031 17.4 0.2 2.1 1 1 1 2 2 2 1 F-box PRANC PF09372.10 EMG49027.1 - 0.054 13.8 1.3 0.22 11.9 0.1 2.5 2 0 0 2 2 2 0 PRANC domain zf-C3HC PF07967.13 EMG49028.1 - 1.6e-29 102.6 2.5 1.5e-27 96.3 0.4 2.6 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EMG49028.1 - 0.036 14.2 6.3 0.063 13.4 0.0 3.3 3 1 0 3 3 3 0 Rsm1-like BIR PF00653.21 EMG49028.1 - 0.042 14.5 0.6 0.41 11.3 0.3 2.6 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain tRNA_synthFbeta PF17759.1 EMG49030.1 - 1.3e-40 139.1 0.0 2.1e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EMG49030.1 - 4.6e-31 106.9 1.6 1.1e-29 102.5 0.2 2.5 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EMG49030.1 - 3.3e-25 88.8 0.1 5.6e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EMG49030.1 - 1.2e-20 73.5 0.1 2.9e-17 62.7 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain NFACT-C PF11923.8 EMG49031.1 - 2.2e-34 117.6 0.0 2.2e-34 117.6 0.0 3.4 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 EMG49031.1 - 1.2e-21 77.0 31.1 1.2e-21 77.0 31.1 3.2 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EMG49031.1 - 1.1e-19 71.0 0.0 3.8e-19 69.3 0.0 2.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain NCD2 PF04905.13 EMG49031.1 - 0.009 16.0 3.6 0.089 12.8 0.2 2.8 2 0 0 2 2 2 1 NAB conserved region 2 (NCD2) Epimerase PF01370.21 EMG49032.1 - 7.3e-18 64.9 0.0 1.1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG49032.1 - 6.9e-12 44.9 0.0 9.3e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMG49032.1 - 1.2e-08 34.8 0.2 2e-08 34.0 0.2 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMG49032.1 - 3e-08 33.8 0.0 6.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMG49032.1 - 2.6e-06 27.2 0.5 0.0029 17.2 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.25 EMG49032.1 - 6.3e-06 25.8 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EMG49032.1 - 3.7e-05 23.0 0.2 0.0023 17.1 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 EMG49032.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MtrA PF04208.14 EMG49032.1 - 0.14 11.8 0.9 0.45 10.1 0.0 2.0 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A SIR2 PF02146.17 EMG49033.1 - 6.4e-62 208.6 0.0 1e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Eaf7 PF07904.13 EMG49033.1 - 0.068 13.6 2.8 0.16 12.4 2.8 1.7 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 Bac_DnaA PF00308.18 EMG49033.1 - 0.097 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein MutS_V PF00488.21 EMG49034.1 - 4.4e-53 180.1 0.8 7.3e-53 179.4 0.1 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EMG49034.1 - 3.3e-30 105.7 6.8 1e-29 104.1 6.8 1.9 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EMG49034.1 - 1e-08 35.4 0.2 2.6e-08 34.1 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EMG49034.1 - 1.7e-07 31.6 0.1 4.7e-07 30.2 0.1 1.8 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.6 EMG49034.1 - 0.0054 16.8 0.3 0.28 11.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain KdpD PF02702.17 EMG49034.1 - 0.051 13.0 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain DUF2624 PF11116.8 EMG49034.1 - 0.48 11.3 5.9 3.6 8.5 0.7 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2624) Methyltransf_34 PF11312.8 EMG49035.1 - 2.8e-90 302.7 0.0 4.1e-90 302.1 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase DUF726 PF05277.12 EMG49036.1 - 1.1e-127 425.7 2.8 2e-127 424.9 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF726) ETRAMP PF09716.10 EMG49036.1 - 0.025 14.7 0.1 0.084 12.9 0.1 1.9 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CATSPERG PF15064.6 EMG49036.1 - 0.13 10.0 0.9 0.19 9.5 0.9 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma Hyphal_reg_CWP PF11765.8 EMG49037.1 - 3.1e-101 338.6 22.6 4.7e-101 338.0 22.6 1.3 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 EMG49037.1 - 4.3e-58 192.6 143.6 4e-12 45.5 16.4 7.7 7 0 0 7 7 7 7 Hyphally regulated cell wall GPI-anchored protein 1 Sec16 PF12932.7 EMG49037.1 - 0.0017 18.9 2.5 0.064 13.9 0.2 3.2 1 1 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region FAM124 PF15067.6 EMG49037.1 - 0.025 14.2 1.4 22 4.6 0.0 3.3 3 0 0 3 3 3 0 FAM124 family CopC PF04234.12 EMG49037.1 - 0.13 13.3 23.8 5 8.2 1.7 5.7 1 1 5 6 6 6 0 CopC domain Qn_am_d_aII PF14930.6 EMG49037.1 - 4.2 7.7 7.9 28 5.1 0.1 4.5 2 2 4 6 6 6 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II DEAD PF00270.29 EMG49038.1 - 3.7e-48 163.6 1.3 9.8e-48 162.2 0.1 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG49038.1 - 1.9e-29 102.2 0.1 2.1e-27 95.7 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EMG49038.1 - 0.065 13.5 0.1 0.065 13.5 0.1 2.5 4 0 0 4 4 4 0 AAA domain DUF148 PF02520.17 EMG49040.1 - 0.0011 19.0 0.6 0.37 10.9 0.2 2.4 2 1 0 2 2 2 2 Domain of unknown function DUF148 DUF2247 PF10004.9 EMG49040.1 - 0.01 15.6 0.4 0.016 15.0 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) ZapB PF06005.12 EMG49040.1 - 0.018 15.5 1.5 4.4 7.8 0.0 3.2 3 1 0 3 3 3 0 Cell division protein ZapB DUF4259 PF14078.6 EMG49040.1 - 0.043 14.5 0.5 0.076 13.8 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) DUF5030 PF16433.5 EMG49040.1 - 0.044 13.1 0.1 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5030) DIMCO_N PF16844.5 EMG49040.1 - 0.11 12.9 0.9 2.2 8.7 0.2 2.2 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal ING PF12998.7 EMG49040.1 - 0.13 12.8 2.6 0.17 12.5 0.7 1.9 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF5082 PF16888.5 EMG49040.1 - 0.25 11.6 2.0 1.2 9.4 1.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Tho1_MOS11_C PF18592.1 EMG49040.1 - 0.93 9.3 4.7 1.5 8.7 0.0 2.6 3 0 0 3 3 3 0 Tho1/MOS11 C-terminal domain Tti2 PF10521.9 EMG49041.1 - 1.1e-14 54.6 8.2 1.2e-09 38.2 4.2 2.6 2 1 0 2 2 2 2 Tti2 family Indigoidine_A PF04227.12 EMG49042.1 - 3.3e-99 331.9 0.1 4.8e-99 331.4 0.1 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein Chalcone_2 PF16035.5 EMG49042.1 - 3.6e-56 190.2 1.8 1.8e-55 187.9 0.0 2.6 2 1 0 2 2 2 1 Chalcone isomerase like PfkB PF00294.24 EMG49042.1 - 2.5e-11 43.5 0.1 0.00013 21.4 0.1 3.6 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Chalcone_3 PF16036.5 EMG49042.1 - 5.6e-06 26.6 0.1 0.00074 19.7 0.0 3.0 2 1 0 2 2 2 1 Chalcone isomerase-like DASH_Dad2 PF08654.10 EMG49042.1 - 0.007 16.8 1.1 0.023 15.1 1.1 1.9 1 0 0 1 1 1 1 DASH complex subunit Dad2 NTP_transferase PF00483.23 EMG49043.1 - 2e-53 181.5 0.0 2.7e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EMG49043.1 - 1.1e-10 42.1 0.0 1.6e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EMG49043.1 - 9e-10 37.9 5.1 5.3e-08 32.3 0.9 3.8 2 2 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMG49043.1 - 4.4e-05 23.2 0.6 0.41 10.4 0.1 3.2 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase MMR_HSR1 PF01926.23 EMG49045.1 - 2.2e-05 24.5 0.0 0.00011 22.3 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMG49045.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase GTP_EFTU PF00009.27 EMG49045.1 - 0.047 13.2 0.6 0.36 10.3 0.0 2.3 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EMG49045.1 - 0.05 14.1 0.7 0.13 12.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 EMG49045.1 - 0.089 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rit1_C PF17184.4 EMG49046.1 - 1e-87 294.1 0.1 2.1e-87 293.1 0.1 1.5 1 0 0 1 1 1 1 Rit1 N-terminal domain SPT2 PF08243.11 EMG49046.1 - 2.6e-25 89.1 20.1 2.6e-25 89.1 20.1 2.4 2 0 0 2 2 2 1 SPT2 chromatin protein Init_tRNA_PT PF04179.12 EMG49046.1 - 2.9e-21 75.8 0.1 1.2e-20 73.8 0.1 2.2 1 1 0 1 1 1 1 Rit1 DUSP-like domain FumaraseC_C PF10415.9 EMG49046.1 - 1.8e-10 41.0 0.2 4.3e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus TIP120 PF08623.10 EMG49047.1 - 4.4e-11 42.8 2.9 8.2e-11 42.0 0.2 3.0 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EMG49047.1 - 7.6e-06 25.8 0.3 0.004 17.3 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 EMG49047.1 - 1.2e-05 25.6 0.0 0.018 15.4 0.0 3.6 3 0 0 3 3 3 1 HEAT repeats RTP1_C1 PF10363.9 EMG49047.1 - 0.0025 18.0 3.0 0.048 13.8 0.1 4.0 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 EMG49047.1 - 0.0036 17.2 0.9 0.079 12.9 0.0 3.3 3 0 0 3 3 3 1 UME (NUC010) domain TAF6_C PF07571.13 EMG49047.1 - 0.069 13.5 0.0 1.4 9.3 0.0 3.2 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 EMG49047.1 - 0.082 13.0 0.1 0.9 9.7 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EMG49047.1 - 0.11 13.1 0.0 0.62 10.6 0.0 2.4 1 0 0 1 1 1 0 HEAT-like repeat CLASP_N PF12348.8 EMG49047.1 - 0.13 11.8 0.0 0.13 11.8 0.0 4.0 5 1 1 6 6 6 0 CLASP N terminal MINDY_DUB PF04424.13 EMG49047.1 - 0.48 10.4 7.4 4.9 7.2 0.2 3.9 3 0 0 3 3 3 0 MINDY deubiquitinase Cnd1 PF12717.7 EMG49047.1 - 4.6 7.3 17.4 0.081 13.0 0.5 4.7 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF2373 PF10180.9 EMG49048.1 - 3.8e-22 77.9 0.3 6.5e-22 77.1 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Peptidase_S49_N PF08496.10 EMG49048.1 - 0.038 14.1 0.5 0.038 14.1 0.5 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Casc1 PF12366.8 EMG49048.1 - 9 5.7 13.8 2.6 7.5 4.9 2.2 2 1 0 2 2 2 0 Cancer susceptibility candidate 1 Nop PF01798.18 EMG49049.1 - 0.013 14.9 0.6 0.022 14.2 0.2 1.5 1 1 0 1 1 1 0 snoRNA binding domain, fibrillarin Phage_connect_1 PF05135.13 EMG49049.1 - 0.015 15.8 1.1 0.019 15.5 0.9 1.3 1 1 0 1 1 1 0 Phage gp6-like head-tail connector protein Cnd1 PF12717.7 EMG49049.1 - 0.017 15.1 0.7 0.02 14.9 0.7 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 FliS PF02561.14 EMG49049.1 - 0.029 14.7 0.3 0.034 14.4 0.3 1.2 1 0 0 1 1 1 0 Flagellar protein FliS Nmad2 PF18753.1 EMG49049.1 - 0.039 13.4 1.4 0.044 13.2 1.4 1.1 1 0 0 1 1 1 0 Nucleotide modification associated domain 2 Nas2_N PF18265.1 EMG49049.1 - 0.098 12.6 1.4 0.8 9.7 0.1 2.1 2 0 0 2 2 2 0 Nas2 N_terminal domain DUF3552 PF12072.8 EMG49050.1 - 0.023 14.1 0.1 0.025 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Val_tRNA-synt_C PF10458.9 EMG49050.1 - 0.034 14.4 2.7 34 4.8 0.0 4.2 1 1 3 4 4 4 0 Valyl tRNA synthetase tRNA binding arm Myosin_tail_1 PF01576.19 EMG49050.1 - 0.049 11.4 0.1 0.06 11.2 0.1 1.2 1 0 0 1 1 1 0 Myosin tail PEARLI-4 PF05278.12 EMG49050.1 - 0.09 12.3 3.5 0.57 9.7 1.0 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) BAR PF03114.18 EMG49050.1 - 0.14 11.8 0.5 2.1 8.0 0.0 2.3 1 1 1 2 2 2 0 BAR domain FPP PF05911.11 EMG49050.1 - 0.25 9.5 0.0 0.25 9.5 0.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil TRPM_tetra PF16519.5 EMG49050.1 - 0.26 11.4 0.0 2.7 8.2 0.0 2.6 2 1 1 3 3 3 0 Tetramerisation domain of TRPM HAD PF12710.7 EMG49051.1 - 1.1e-11 45.5 0.0 3.1e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMG49051.1 - 0.00032 21.1 0.1 0.00078 19.8 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EMG49051.1 - 0.00039 20.0 0.1 0.00053 19.6 0.1 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 EMG49051.1 - 0.00053 19.5 1.8 0.64 9.4 0.2 3.0 3 0 0 3 3 3 2 Putative Phosphatase HAD_2 PF13419.6 EMG49051.1 - 0.0018 18.4 0.1 0.014 15.5 0.1 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TPR_14 PF13428.6 EMG49052.1 - 1.5e-11 44.1 0.6 0.048 14.5 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMG49052.1 - 1.3e-09 37.5 5.8 0.00031 20.4 0.7 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMG49052.1 - 5.2e-09 35.5 8.9 0.0008 19.3 0.5 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EMG49052.1 - 8.4e-08 32.3 1.1 0.00025 21.1 0.6 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMG49052.1 - 2.6e-06 28.0 1.5 0.31 11.7 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMG49052.1 - 7.3e-06 25.6 12.2 0.013 15.2 1.2 5.7 4 1 0 4 4 4 2 TPR repeat TPR_8 PF13181.6 EMG49052.1 - 8.3e-06 25.6 6.5 0.042 14.1 1.2 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMG49052.1 - 0.00035 20.8 0.2 0.00035 20.8 0.2 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMG49052.1 - 0.021 15.4 5.6 17 6.3 0.4 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 EMG49052.1 - 0.13 11.4 0.0 0.13 11.4 0.0 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat Borrelia_P83 PF05262.11 EMG49052.1 - 0.14 10.6 8.1 0.26 9.7 8.1 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_17 PF13431.6 EMG49052.1 - 0.2 12.1 14.7 12 6.6 0.1 6.3 5 1 1 6 6 5 0 Tetratricopeptide repeat ChAPs PF09295.10 EMG49052.1 - 0.22 10.5 7.0 2.9 6.8 0.1 3.6 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 EMG49052.1 - 0.4 9.5 7.2 6.1 5.6 6.0 2.5 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 EMG49052.1 - 3.3 8.3 22.8 0.065 13.7 1.0 5.2 5 1 1 6 6 5 0 Tetratricopeptide repeat Lyase_1 PF00206.20 EMG49053.1 - 1e-47 163.1 0.0 1.1e-47 162.9 0.0 1.0 1 0 0 1 1 1 1 Lyase DUF3385 PF11865.8 EMG49053.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) PQ-loop PF04193.14 EMG49055.1 - 2.1e-22 78.6 8.7 5.9e-19 67.6 0.3 2.8 2 0 0 2 2 2 2 PQ loop repeat PalH PF08733.10 EMG49055.1 - 0.096 11.7 7.6 0.08 11.9 5.7 1.9 1 1 1 2 2 2 0 PalH/RIM21 Rad4 PF03835.15 EMG49056.1 - 9e-36 122.8 6.5 2.7e-35 121.2 6.5 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EMG49056.1 - 4.9e-24 84.5 0.1 1.6e-23 82.9 0.1 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EMG49056.1 - 1.9e-18 66.0 0.0 3.8e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EMG49056.1 - 2.2e-05 25.3 5.7 0.073 14.0 0.1 3.5 2 1 1 3 3 3 2 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EMG49056.1 - 0.00078 19.9 0.0 0.0023 18.4 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Glycos_transf_1 PF00534.20 EMG49056.1 - 0.11 12.1 0.1 0.3 10.6 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Pox_MCEL PF03291.16 EMG49057.1 - 1.5e-111 372.7 0.3 2.4e-111 372.1 0.3 1.3 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EMG49057.1 - 5.2e-07 30.3 0.0 0.00019 22.1 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG49057.1 - 2.3e-05 25.1 0.4 0.00018 22.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG49057.1 - 0.00028 21.5 0.0 0.5 11.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EMG49057.1 - 0.001 18.8 0.1 0.0071 16.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EMG49057.1 - 0.034 13.3 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FSH1 PF03959.13 EMG49058.1 - 3.1e-57 193.6 0.0 3.6e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 EMG49058.1 - 0.0011 19.0 0.0 0.016 15.1 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Translin PF01997.16 EMG49059.1 - 5.3e-10 39.6 0.1 8.9e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Translin family Suf PF05843.14 EMG49059.1 - 0.053 13.5 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3885 PF13021.6 EMG49059.1 - 0.071 13.2 0.1 0.36 11.0 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) bZIP_1 PF00170.21 EMG49059.1 - 0.098 12.8 1.2 0.14 12.3 0.2 1.7 2 0 0 2 2 2 0 bZIP transcription factor TMF_TATA_bd PF12325.8 EMG49061.1 - 2.2e-33 114.9 20.0 2.2e-33 114.9 20.0 6.5 3 2 3 6 6 6 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EMG49061.1 - 1e-15 57.5 14.9 1e-15 57.5 14.9 9.4 6 3 4 10 10 10 4 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 EMG49061.1 - 0.0096 16.2 4.1 0.0096 16.2 4.1 8.1 5 4 1 7 7 7 2 ABC transporter C-terminal domain DUF2852 PF11014.8 EMG49062.1 - 0.037 14.2 0.6 0.037 14.2 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) zf-C2H2 PF00096.26 EMG49062.1 - 0.29 11.7 4.1 0.17 12.4 1.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type CAP_GLY PF01302.25 EMG49063.1 - 2.5e-14 53.0 0.0 5.1e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain HAUS-augmin3 PF14932.6 EMG49063.1 - 3.6e-06 26.8 23.2 0.0026 17.4 6.2 2.1 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 3 CLIP1_ZNF PF16641.5 EMG49063.1 - 0.0029 17.4 1.0 0.0052 16.6 1.0 1.3 1 0 0 1 1 1 1 CLIP1 zinc knuckle Tropomyosin_1 PF12718.7 EMG49063.1 - 0.003 17.7 17.3 0.003 17.7 17.3 2.6 1 1 2 3 3 3 1 Tropomyosin like Filament PF00038.21 EMG49063.1 - 0.0032 17.1 26.6 0.039 13.5 9.3 2.4 1 1 0 2 2 2 2 Intermediate filament protein MAD PF05557.13 EMG49063.1 - 0.0044 15.4 23.9 0.0062 15.0 23.9 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Rrn6 PF10214.9 EMG49063.1 - 0.0087 14.6 6.6 0.012 14.2 6.6 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor SlyX PF04102.12 EMG49063.1 - 0.018 15.6 22.8 0.023 15.3 1.5 4.6 2 1 2 4 4 4 0 SlyX MeaB PF03308.16 EMG49063.1 - 0.032 13.2 0.9 0.052 12.5 0.9 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Spc7 PF08317.11 EMG49063.1 - 0.065 12.1 29.7 0.57 9.0 4.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EMG49063.1 - 0.1 12.6 32.0 0.14 12.1 1.2 4.6 3 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding MscS_porin PF12795.7 EMG49063.1 - 0.12 11.9 23.2 16 5.0 22.2 3.0 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 EMG49063.1 - 0.17 11.2 17.4 1 8.6 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HP0268 PF18618.1 EMG49063.1 - 0.21 12.1 2.6 0.2 12.1 1.1 1.8 1 1 0 1 1 1 0 HP0268 SAB PF04382.13 EMG49063.1 - 0.36 10.9 8.3 0.19 11.8 1.6 3.4 3 0 0 3 3 3 0 SAB domain DUF745 PF05335.13 EMG49063.1 - 0.49 10.1 15.3 3.9 7.1 0.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF5082 PF16888.5 EMG49063.1 - 0.49 10.7 26.3 0.089 13.1 10.5 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) HIP1_clath_bdg PF16515.5 EMG49063.1 - 1.1 9.9 25.3 0.11 13.1 7.4 3.9 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Uds1 PF15456.6 EMG49063.1 - 1.3 9.2 18.1 0.098 12.8 8.0 3.3 1 1 2 3 3 3 0 Up-regulated During Septation zf-C4H2 PF10146.9 EMG49063.1 - 1.4 9.2 20.7 3.1 8.1 20.1 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein Syntaxin-6_N PF09177.11 EMG49063.1 - 1.7 9.3 18.3 1.9 9.1 0.6 3.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Csm1_N PF18504.1 EMG49063.1 - 1.7 9.0 26.8 1.7 9.1 2.5 4.6 2 1 3 5 5 5 0 Csm1 N-terminal domain KxDL PF10241.9 EMG49063.1 - 2.3 8.5 19.2 0.97 9.8 5.1 4.1 1 1 2 3 3 3 0 Uncharacterized conserved protein P4Ha_N PF08336.11 EMG49063.1 - 2.5 8.1 17.3 13 5.8 13.7 3.4 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PRKG1_interact PF15898.5 EMG49063.1 - 2.8 8.9 25.9 0.17 12.8 8.1 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 EMG49063.1 - 3.8 7.6 29.0 5.9 7.0 19.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 EMG49063.1 - 3.9 6.8 28.8 9.7 5.5 8.8 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 EMG49063.1 - 4.5 6.7 19.1 70 2.8 19.1 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF641 PF04859.12 EMG49063.1 - 5.7 7.3 20.7 1.2 9.5 8.1 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF724 PF05266.14 EMG49063.1 - 6.7 6.5 23.1 1.7 8.4 7.8 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) SOAR PF16533.5 EMG49063.1 - 7.6 6.6 13.1 0.41 10.6 4.6 2.7 1 1 2 3 3 3 0 STIM1 Orai1-activating region DASH_Spc19 PF08287.11 EMG49063.1 - 9.8 6.0 25.5 1.5 8.7 3.6 2.9 1 1 2 3 3 3 0 Spc19 Abhydrolase_1 PF00561.20 EMG49064.1 - 5.8e-18 65.5 0.0 7.3e-17 61.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMG49064.1 - 2.9e-13 50.9 0.0 3.7e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMG49064.1 - 1.5e-06 27.7 0.0 1.4e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 EMG49064.1 - 0.00028 20.5 0.0 0.0011 18.6 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_8 PF06259.12 EMG49064.1 - 0.037 13.7 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Thioesterase PF00975.20 EMG49064.1 - 0.092 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain ANAPC4_WD40 PF12894.7 EMG49065.1 - 0.079 13.3 1.9 1.4 9.3 0.1 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Keratin_2_head PF16208.5 EMG49066.1 - 1.2 9.3 11.7 2 8.6 11.7 1.3 1 0 0 1 1 1 0 Keratin type II head NUP214 PF16755.5 EMG49067.1 - 1.2e-25 90.5 8.2 8.4e-25 87.8 8.2 1.9 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 IKI3 PF04762.12 EMG49067.1 - 0.02 12.9 0.0 0.024 12.6 0.0 1.1 1 0 0 1 1 1 0 IKI3 family AbiJ_NTD4 PF18863.1 EMG49067.1 - 0.08 13.4 0.9 0.16 12.4 0.9 1.4 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 Keratin_2_head PF16208.5 EMG49067.1 - 0.54 10.4 25.9 0.85 9.7 25.9 1.3 1 0 0 1 1 1 0 Keratin type II head Fcf2 PF08698.11 EMG49068.1 - 2.2e-39 133.8 6.7 2.2e-39 133.8 6.7 2.4 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing Integrin_alpha PF00357.20 EMG49068.1 - 0.87 9.7 5.0 2.9 8.1 0.1 3.5 3 0 0 3 3 3 0 Integrin alpha cytoplasmic region STD1 PF17235.2 EMG49069.1 - 8.6e-60 201.9 10.0 8.6e-60 201.9 10.0 1.6 1 1 1 2 2 2 1 STD1/MTH1 Bot1p PF12298.8 EMG49069.1 - 0.048 13.8 1.2 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein FBPase PF00316.20 EMG49070.1 - 4.2e-79 264.4 0.8 5.6e-79 264.0 0.8 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EMG49070.1 - 0.021 14.4 0.0 0.047 13.2 0.0 1.6 2 0 0 2 2 2 0 Inositol monophosphatase family SecY PF00344.20 EMG49072.1 - 9.9e-66 222.1 8.7 1.3e-65 221.6 8.7 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EMG49072.1 - 6.5e-17 61.1 0.2 2.1e-16 59.5 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p SdpI PF13630.6 EMG49072.1 - 0.16 12.1 0.2 0.16 12.1 0.2 3.2 5 0 0 5 5 5 0 SdpI/YhfL protein family DUF313 PF03754.13 EMG49073.1 - 0.04 14.1 0.3 0.045 14.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF313) Cu_amine_oxidN1 PF07833.11 EMG49074.1 - 0.15 12.5 0.0 0.28 11.7 0.0 1.4 1 1 0 1 1 1 0 Copper amine oxidase N-terminal domain Zn_clus PF00172.18 EMG49076.1 - 6.2e-06 26.2 5.9 9e-06 25.7 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP68 PF16969.5 EMG49077.1 - 8.9e-56 190.0 11.8 2e-54 185.6 11.8 2.7 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 UAA PF08449.11 EMG49077.1 - 1.8e-33 116.1 27.5 1.6e-20 73.6 6.0 3.5 2 1 1 3 3 3 2 UAA transporter family DHHC PF01529.20 EMG49077.1 - 2e-32 112.1 16.1 2e-32 112.1 16.1 4.3 3 1 0 3 3 3 1 DHHC palmitoyltransferase LapA_dom PF06305.11 EMG49077.1 - 0.38 10.6 6.9 16 5.4 0.4 4.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain NAD_kinase PF01513.21 EMG49079.1 - 5.2e-58 196.5 0.0 6.7e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EMG49079.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Hist_deacetyl PF00850.19 EMG49080.1 - 3.7e-82 276.2 0.0 6.4e-82 275.5 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain FAM181 PF15238.6 EMG49081.1 - 0.085 12.7 2.4 0.31 10.9 0.0 2.0 1 1 0 2 2 2 0 FAM181 NOA36 PF06524.12 EMG49081.1 - 3.5 6.9 7.5 4.7 6.4 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein Histone PF00125.24 EMG49082.1 - 6.4e-51 172.1 1.8 7.1e-51 172.0 1.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EMG49082.1 - 6.5e-06 26.4 0.0 9.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EMG49082.1 - 4.6e-05 23.5 0.3 7.7e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EMG49082.1 - 9.4e-05 23.0 0.8 0.00012 22.7 0.8 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EMG49082.1 - 0.0053 17.0 0.4 0.0087 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Oxidored_q6 PF01058.22 EMG49084.1 - 1.1e-22 80.3 0.1 1.7e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NUDIX PF00293.28 EMG49085.1 - 3.4e-12 46.5 0.0 5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RHH_5 PF07878.11 EMG49085.1 - 0.04 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Phage_holin_3_1 PF05106.12 EMG49086.1 - 0.019 15.4 0.3 2.2 8.7 0.1 2.9 2 1 0 2 2 2 0 Phage holin family (Lysis protein S) Zn_ribbon_17 PF17120.5 EMG49086.1 - 0.022 14.3 0.1 0.063 12.9 0.1 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EMG49086.1 - 0.11 12.7 3.5 0.37 11.0 0.5 3.0 3 0 0 3 3 3 0 FANCL C-terminal domain RINGv PF12906.7 EMG49086.1 - 0.51 10.5 2.9 0.45 10.7 1.1 1.9 2 0 0 2 2 2 0 RING-variant domain TPR_1 PF00515.28 EMG49087.1 - 1.8e-51 169.9 27.9 2.7e-07 30.1 0.0 11.0 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EMG49087.1 - 3e-49 161.2 22.4 1.2e-05 25.0 0.0 10.7 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EMG49087.1 - 4.8e-32 107.5 18.4 0.0029 17.7 0.0 11.5 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_16 PF13432.6 EMG49087.1 - 2.4e-28 98.5 13.5 3.4e-05 24.4 0.0 6.7 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EMG49087.1 - 5.6e-28 96.4 28.5 6.2e-06 25.8 0.0 9.6 4 3 6 10 10 10 8 TPR repeat TPR_17 PF13431.6 EMG49087.1 - 1.3e-27 94.1 28.5 0.00063 19.9 0.2 10.7 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 EMG49087.1 - 2e-26 90.4 21.8 7.6e-05 23.2 0.2 9.7 4 2 6 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 EMG49087.1 - 1.2e-20 73.6 36.4 5e-05 23.5 1.6 9.1 5 2 4 9 9 9 7 Tetratricopeptide repeat TPR_9 PF13371.6 EMG49087.1 - 1.3e-20 73.3 13.6 0.013 15.6 0.1 7.4 3 2 2 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 EMG49087.1 - 1.8e-17 62.0 12.6 0.031 14.3 0.1 9.2 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMG49087.1 - 2.1e-17 63.4 38.3 0.00038 20.9 0.4 7.9 6 3 1 7 7 6 6 Tetratricopeptide repeat TPR_6 PF13174.6 EMG49087.1 - 1.9e-16 59.5 21.3 0.053 14.2 0.0 9.9 10 0 0 10 10 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG49087.1 - 2.1e-09 37.4 10.3 0.00013 22.1 1.6 3.8 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EMG49087.1 - 0.00032 20.0 25.3 0.078 12.2 0.0 5.4 3 3 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EMG49087.1 - 0.0042 16.9 19.6 0.39 10.6 0.4 7.8 8 1 1 9 9 9 1 Tetratricopeptide repeat ChAPs PF09295.10 EMG49087.1 - 0.0052 15.8 0.1 0.33 9.9 0.0 3.1 3 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF1824 PF08854.10 EMG49087.1 - 0.037 13.9 1.1 0.13 12.2 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) TOM20_plant PF06552.12 EMG49087.1 - 0.052 13.3 4.4 2.2 8.0 0.0 3.9 4 1 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 RRM_1 PF00076.22 EMG49088.1 - 4.9e-42 141.6 0.0 6.5e-17 61.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMG49088.1 - 0.00012 22.0 0.0 0.0048 16.9 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EMG49088.1 - 0.0009 19.3 0.0 0.03 14.4 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM PF05172.13 EMG49088.1 - 0.0059 16.5 0.0 1.5 8.9 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EMG49088.1 - 0.01 15.9 0.0 0.01 15.9 0.0 2.6 4 0 0 4 4 4 0 RNA binding motif RRM_occluded PF16842.5 EMG49088.1 - 0.011 15.5 0.0 0.71 9.8 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif MAS20 PF02064.15 EMG49088.1 - 0.11 12.6 0.2 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 MAS20 protein import receptor SUIM_assoc PF16619.5 EMG49088.1 - 0.72 10.0 7.6 0.23 11.6 3.4 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Utp14 PF04615.13 EMG49089.1 - 5.2 5.5 12.9 7.7 5.0 12.9 1.3 1 0 0 1 1 1 0 Utp14 protein Ribosomal_L7Ae PF01248.26 EMG49090.1 - 1.2e-24 85.8 0.7 1.6e-24 85.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Gin PF10764.9 EMG49090.1 - 0.014 15.3 0.8 0.024 14.6 0.8 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin SBD_N PF07005.11 EMG49090.1 - 0.022 14.5 0.1 0.028 14.2 0.1 1.1 1 0 0 1 1 1 0 Sugar-binding N-terminal domain NTP_transf_3 PF12804.7 EMG49090.1 - 0.026 14.9 0.1 0.038 14.3 0.1 1.4 1 1 0 1 1 1 0 MobA-like NTP transferase domain KNOX2 PF03791.13 EMG49090.1 - 0.089 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 KNOX2 domain Prominin PF05478.11 EMG49091.1 - 1.1 7.1 7.6 2 6.2 7.6 1.4 1 0 0 1 1 1 0 Prominin Med9 PF07544.13 EMG49091.1 - 1.7 8.8 10.1 5.7 7.1 3.0 3.6 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_II PF06009.12 EMG49091.1 - 2.7 8.0 11.4 4.8 7.2 0.3 2.4 2 0 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 EMG49091.1 - 5.2 7.6 9.0 12 6.5 0.9 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cornichon PF03311.14 EMG49092.1 - 7.3e-52 174.8 11.0 8.4e-52 174.6 11.0 1.0 1 0 0 1 1 1 1 Cornichon protein Claudin_3 PF06653.11 EMG49092.1 - 0.025 14.5 6.6 0.05 13.5 6.6 1.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like HRI1 PF16815.5 EMG49093.1 - 3.7e-49 167.5 0.1 4.1e-49 167.3 0.1 1.0 1 0 0 1 1 1 1 Protein HRI1 LRR_4 PF12799.7 EMG49094.1 - 2e-21 75.7 67.2 3.1e-06 27.4 3.6 8.5 4 2 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG49094.1 - 5.1e-20 71.0 54.4 4.2e-07 29.6 2.1 7.7 5 2 3 8 8 8 6 Leucine rich repeat LRR_9 PF14580.6 EMG49094.1 - 2.7e-08 33.5 29.8 0.0057 16.2 8.6 5.2 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 EMG49094.1 - 1.3e-05 24.8 36.5 3.5 7.9 0.1 11.9 10 2 2 12 12 12 3 Leucine Rich repeat DUF3272 PF11676.8 EMG49094.1 - 0.0056 16.9 1.2 0.13 12.6 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3272) Zn_clus PF00172.18 EMG49095.1 - 3.9e-07 30.1 7.7 7.6e-07 29.2 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3589 PF12141.8 EMG49096.1 - 2.5e-182 606.9 7.9 3.5e-182 606.4 7.9 1.2 1 0 0 1 1 1 1 Beta-mannosyltransferases DUF4473 PF14747.6 EMG49096.1 - 0.0018 18.8 0.4 0.0053 17.3 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) GDI PF00996.18 EMG49097.1 - 7.3e-41 140.1 3.8 1.6e-39 135.7 1.0 2.3 2 1 0 2 2 2 2 GDP dissociation inhibitor FAD_binding_3 PF01494.19 EMG49097.1 - 0.031 13.5 0.1 0.17 11.1 0.0 2.2 2 1 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 EMG49097.1 - 0.087 13.1 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ENTH PF01417.20 EMG49098.1 - 2.2e-37 127.9 1.5 3e-37 127.4 1.5 1.2 1 0 0 1 1 1 1 ENTH domain Pap_E4 PF02711.14 EMG49098.1 - 2.3 9.3 17.3 1.4 9.9 9.0 2.7 2 1 0 2 2 2 0 E4 protein ubiquitin PF00240.23 EMG49099.1 - 5.4e-102 333.6 13.3 1.9e-33 114.0 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EMG49099.1 - 1.3e-48 162.7 13.8 1.2e-15 57.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMG49099.1 - 7.6e-18 64.8 6.1 0.00026 21.4 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 EMG49099.1 - 1.7e-12 47.1 1.7 0.016 15.1 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EMG49099.1 - 1.8e-12 47.5 2.2 0.016 15.6 0.1 3.1 1 1 2 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMG49099.1 - 4.8e-11 42.8 1.3 0.073 13.2 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EMG49099.1 - 7.3e-10 39.3 0.3 0.21 12.1 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EMG49099.1 - 2.5e-08 33.9 0.2 0.41 10.4 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EMG49099.1 - 2.4e-06 27.5 16.0 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 EMG49099.1 - 8.5e-05 22.7 1.0 8 6.7 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 EMG49099.1 - 0.00015 21.5 2.1 6.9 6.6 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF2870 PF11069.8 EMG49099.1 - 0.00028 21.2 0.0 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 EMG49099.1 - 0.00062 19.2 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 EMG49099.1 - 0.0011 19.6 0.1 34 5.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain YcgR_2 PF12945.7 EMG49099.1 - 0.003 17.7 2.9 19 5.5 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR UDP-g_GGTase PF06427.11 EMG49099.1 - 0.0069 16.5 3.0 4.5 7.4 0.0 3.1 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EMG49099.1 - 0.0083 15.6 0.0 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) DUF493 PF04359.14 EMG49099.1 - 0.031 14.9 0.0 95 3.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 EMG49099.1 - 0.031 14.0 0.0 71 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 EMG49099.1 - 0.032 14.8 0.3 96 3.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain ORF11CD3 PF10549.9 EMG49099.1 - 0.088 12.9 0.0 62 3.8 0.0 3.4 3 0 0 3 3 3 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EMG49099.1 - 0.12 12.5 2.6 72 3.6 0.1 3.2 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 EMG49099.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif Myosin_N PF02736.19 EMG49099.1 - 0.27 11.1 3.4 76 3.3 0.0 4.3 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 EMG49099.1 - 0.47 10.1 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Plexin_cytopl PF08337.12 EMG49099.1 - 0.76 8.4 11.0 11 4.6 0.4 3.9 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 EMG49099.1 - 0.85 9.4 5.0 67 3.3 0.1 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain FlgD_ig PF13860.6 EMG49099.1 - 2.8 7.9 4.9 1.2e+02 2.6 0.1 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Ecm29 PF13001.7 EMG49100.1 - 4.7e-139 464.3 0.6 4.7e-139 464.3 0.6 2.7 3 0 0 3 3 3 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 EMG49100.1 - 2.5e-06 28.0 5.4 0.046 14.3 0.0 6.7 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EMG49100.1 - 0.00061 19.4 1.9 1.7 8.2 0.2 4.3 4 1 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 EMG49100.1 - 0.00071 19.6 16.1 3.3 8.2 0.0 8.5 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 EMG49100.1 - 0.0029 18.0 5.7 52 4.3 0.0 6.6 7 0 0 7 7 7 0 HEAT repeats UTP15_C PF09384.10 EMG49100.1 - 1.3 8.7 5.7 1.8 8.3 0.7 3.5 3 0 0 3 3 3 0 UTP15 C terminal IF-2B PF01008.17 EMG49101.1 - 4.2e-77 259.1 1.5 2.1e-39 135.4 0.3 2.8 3 0 0 3 3 3 2 Initiation factor 2 subunit family DndE PF08870.11 EMG49101.1 - 0.0023 18.2 0.2 0.25 11.6 0.0 3.4 3 0 0 3 3 3 1 DNA sulphur modification protein DndE Roughex PF06020.11 EMG49101.1 - 0.43 9.6 6.7 1 8.4 6.7 1.6 1 0 0 1 1 1 0 Drosophila roughex protein Ndc1_Nup PF09531.10 EMG49101.1 - 2 7.0 10.9 3.2 6.3 10.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4228 PF14009.6 EMG49101.1 - 9.7 6.5 8.5 18 5.7 7.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) PhoLip_ATPase_C PF16212.5 EMG49102.1 - 4.3e-84 282.2 22.2 4.3e-84 282.2 22.2 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMG49102.1 - 1.5e-25 88.6 4.6 4.4e-25 87.1 4.6 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EMG49102.1 - 1.5e-12 48.2 0.2 4.2e-07 30.5 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMG49102.1 - 2.4e-11 43.6 0.0 1.2e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EMG49102.1 - 1.3e-05 24.8 0.0 2.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EMG49102.1 - 0.0028 17.4 0.1 0.03 14.1 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aldedh PF00171.22 EMG49103.1 - 8.2e-14 51.0 0.6 4.3e-13 48.6 0.6 1.8 1 1 0 1 1 1 1 Aldehyde dehydrogenase family URO-D PF01208.17 EMG49103.1 - 0.0022 17.2 0.0 0.0032 16.7 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) KKLCAg1 PF15204.6 EMG49103.1 - 0.71 10.0 3.9 0.95 9.6 0.0 2.4 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 NAD_binding_7 PF13241.6 EMG49104.1 - 2.5e-29 101.8 0.0 5.3e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 EMG49104.1 - 1.2e-12 47.0 0.1 2.5e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 EMG49104.1 - 7.7e-12 44.7 0.1 1.8e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal LSDAT_prok PF18171.1 EMG49104.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Eisosome1 PF12757.7 EMG49105.1 - 1.9e-13 50.7 1.4 1.9e-13 50.7 1.4 9.9 4 2 0 5 5 5 1 Eisosome protein 1 Romo1 PF10247.9 EMG49105.1 - 0.79 10.1 4.6 1.6 9.1 4.6 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 RRM_1 PF00076.22 EMG49106.1 - 5.9e-27 93.3 0.5 3.6e-19 68.3 0.2 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMG49106.1 - 0.00071 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EMG49106.1 - 0.03 14.4 0.0 0.39 10.9 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif SNAD2 PF18745.1 EMG49106.1 - 0.11 12.1 2.7 0.15 11.8 0.0 2.4 2 1 1 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 2 Mnd1 PF03962.15 EMG49107.1 - 0.053 13.8 0.5 9.1 6.7 0.2 2.7 2 0 0 2 2 2 0 Mnd1 HTH domain RabGAP-TBC PF00566.18 EMG49107.1 - 2 8.0 23.6 0.15 11.6 0.3 4.7 5 1 0 5 5 5 0 Rab-GTPase-TBC domain Kelch_3 PF13415.6 EMG49108.1 - 1.7e-10 40.9 0.0 1.7e-07 31.3 0.0 3.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_4 PF13418.6 EMG49108.1 - 1.1e-08 34.9 0.3 1.2e-05 25.2 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 EMG49108.1 - 5.3e-08 32.7 0.0 0.0028 17.6 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EMG49108.1 - 1.5e-06 28.2 1.0 4.9e-05 23.5 0.0 3.6 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 EMG49108.1 - 5.5e-06 26.1 0.0 0.00068 19.5 0.0 3.4 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 EMG49108.1 - 0.00015 21.3 0.0 0.022 14.3 0.0 3.3 3 0 0 3 3 3 1 Kelch motif JAB PF01398.21 EMG49109.1 - 1.3e-06 28.4 0.0 4.6e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Remorin_C PF03763.13 EMG49109.1 - 0.013 15.4 4.7 0.021 14.7 4.7 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region Aldo_ket_red PF00248.21 EMG49110.1 - 1.1e-47 162.7 0.2 1e-45 156.2 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_2 PF00152.20 EMG49111.1 - 6e-77 258.8 0.4 9.2e-77 258.2 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMG49111.1 - 6.3e-11 42.1 0.1 1.3e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMG49111.1 - 2.2e-07 30.6 0.0 0.0043 16.6 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Staph_opine_DH PF10100.9 EMG49111.1 - 0.092 11.4 0.0 0.34 9.5 0.0 1.8 2 0 0 2 2 2 0 Staphylopine dehydrogenase FtsJ PF01728.19 EMG49112.1 - 1.7e-70 236.7 0.0 2.2e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EMG49112.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EMG49112.1 - 0.013 15.2 0.0 0.51 10.1 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EMG49112.1 - 0.016 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EMG49112.1 - 0.18 12.5 0.0 0.73 10.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain zf-RING_2 PF13639.6 EMG49113.1 - 1.1e-11 44.8 2.9 1.8e-11 44.2 2.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EMG49113.1 - 2.7e-06 27.5 5.2 1.8e-05 24.9 5.1 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EMG49113.1 - 3.3e-06 27.0 0.9 3.3e-06 27.0 0.9 1.6 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EMG49113.1 - 1.8e-05 24.5 2.4 0.019 14.8 0.2 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EMG49113.1 - 3.7e-05 23.5 3.8 0.0001 22.1 3.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMG49113.1 - 0.0001 22.1 2.0 0.00034 20.4 2.1 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EMG49113.1 - 0.00032 20.7 1.1 0.0005 20.1 1.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 EMG49113.1 - 0.00074 19.7 0.6 0.051 13.8 0.2 2.4 2 0 0 2 2 2 1 zinc-ribbon zf-C3HC4 PF00097.25 EMG49113.1 - 0.0023 17.8 2.2 0.0048 16.7 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMG49113.1 - 0.0038 16.9 2.3 0.0038 16.9 0.6 1.9 2 0 0 2 2 2 1 RING-like zinc finger Baculo_IE-1 PF05290.11 EMG49113.1 - 0.0067 16.4 0.3 0.0094 15.9 0.3 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 EMG49113.1 - 0.014 15.3 0.7 0.032 14.2 0.7 1.6 1 1 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.7 EMG49113.1 - 0.044 13.9 0.6 0.078 13.1 0.6 1.4 1 0 0 1 1 1 0 RING-variant domain zf-Di19 PF05605.12 EMG49113.1 - 0.061 13.6 0.4 15 6.0 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Auto_anti-p27 PF06677.12 EMG49113.1 - 0.09 13.0 1.0 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) U-box PF04564.15 EMG49113.1 - 0.097 12.9 0.1 1.8 8.8 0.0 2.6 2 1 1 3 3 3 0 U-box domain zf-RING_6 PF14835.6 EMG49113.1 - 0.15 11.9 3.5 0.17 11.8 0.6 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_1 PF14446.6 EMG49113.1 - 0.21 11.5 1.5 15 5.6 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.14 EMG49113.1 - 0.33 10.8 7.5 3.3 7.6 2.0 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif Zn-C2H2_12 PF18112.1 EMG49113.1 - 0.4 11.2 2.8 4.9 7.7 0.1 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain CTU2 PF10288.9 EMG49113.1 - 1.6 9.0 5.7 12 6.2 5.7 2.3 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-C3HC4_4 PF15227.6 EMG49113.1 - 2.1 8.5 5.5 13 6.0 5.9 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FAD-oxidase_C PF02913.19 EMG49115.1 - 6.3e-55 186.5 0.0 8.4e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMG49115.1 - 1.1e-39 135.3 0.1 2e-39 134.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lact-deh-memb PF09330.11 EMG49115.1 - 4.3e-05 23.0 0.0 6.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 D-lactate dehydrogenase, membrane binding DUF5591 PF17884.1 EMG49115.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) Yip1 PF04893.17 EMG49116.1 - 1e-10 41.6 21.9 1.9e-10 40.8 21.9 1.3 1 1 0 1 1 1 1 Yip1 domain PGM_PMM_I PF02878.16 EMG49117.1 - 1.2e-36 125.4 0.2 3.9e-20 72.0 0.1 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EMG49117.1 - 1.9e-23 83.0 0.0 5.5e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EMG49117.1 - 2.9e-14 53.2 0.0 4.8e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EMG49117.1 - 6.2e-05 23.1 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Anp1 PF03452.14 EMG49118.1 - 2.3e-117 391.1 0.0 3.5e-117 390.5 0.0 1.3 1 0 0 1 1 1 1 Anp1 TatD_DNase PF01026.21 EMG49119.1 - 8e-30 104.1 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase TIM PF00121.18 EMG49120.1 - 1.4e-59 201.4 0.0 1.6e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase His_Phos_1 PF00300.22 EMG49121.1 - 1.8e-26 93.1 0.0 3.6e-26 92.0 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Baculo_p74_N PF08404.10 EMG49121.1 - 0.037 13.1 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal SUR7 PF06687.12 EMG49122.1 - 1.8e-64 217.3 6.4 2.2e-64 217.0 6.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Prominin PF05478.11 EMG49122.1 - 0.0095 13.9 0.2 0.94 7.3 0.0 2.2 2 0 0 2 2 2 2 Prominin MxiM PF11441.8 EMG49122.1 - 0.057 13.7 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Pilot protein MxiM DUF3139 PF11337.8 EMG49122.1 - 1.3 9.7 3.4 0.99 10.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Collagen PF01391.18 EMG49122.1 - 1.9 8.3 18.9 4.1 7.2 18.9 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF624 PF04854.14 EMG49122.1 - 4.1 7.6 8.5 0.93 9.6 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF624 DUF4231 PF14015.6 EMG49122.1 - 5.6 7.5 7.3 9.3 6.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) NIF PF03031.18 EMG49123.1 - 1.8e-26 92.7 0.4 7.7e-26 90.7 0.0 2.2 3 0 0 3 3 3 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EMG49123.1 - 6e-05 23.3 0.5 0.00023 21.5 0.0 2.3 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain NYD-SP28_assoc PF14775.6 EMG49123.1 - 0.00062 19.8 0.1 0.00062 19.8 0.1 2.0 2 0 0 2 2 2 1 Sperm tail C-terminal domain PTCB-BRCT PF12738.7 EMG49123.1 - 0.001 18.9 0.1 0.0048 16.8 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 EMG49123.1 - 0.0011 19.3 0.0 0.0035 17.7 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Prp19 PF08606.11 EMG49124.1 - 9.8e-30 102.4 2.1 1.8e-29 101.5 2.1 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.15 EMG49124.1 - 6.8e-07 29.4 0.1 2e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EMG49124.1 - 0.016 15.0 0.0 0.051 13.4 0.0 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Aldo_ket_red PF00248.21 EMG49125.1 - 2.1e-49 168.3 0.3 2.3e-47 161.6 0.3 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SPX PF03105.19 EMG49126.1 - 1e-05 25.7 0.1 1e-05 25.7 0.1 3.8 2 2 0 3 3 3 2 SPX domain zf-C2H2 PF00096.26 EMG49127.1 - 1.5e-10 40.9 9.2 2.7e-05 24.4 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG49127.1 - 2.2e-07 31.1 7.4 0.00078 20.1 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EMG49127.1 - 0.00058 20.2 0.5 0.13 12.6 0.4 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EMG49127.1 - 0.0035 17.6 0.2 0.056 13.7 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 EMG49127.1 - 0.0038 17.9 2.4 0.076 13.7 1.7 2.3 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 EMG49127.1 - 0.0061 17.0 9.5 0.096 13.2 2.0 3.0 3 0 0 3 3 3 2 Zinc-finger double domain Actin_micro PF17003.5 EMG49127.1 - 0.016 14.4 0.1 0.038 13.2 0.1 1.5 1 1 0 1 1 1 0 Putative actin-like family DUF2256 PF10013.9 EMG49127.1 - 0.032 14.4 1.0 4 7.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF2321 PF10083.9 EMG49127.1 - 0.051 13.2 0.3 0.11 12.2 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-Di19 PF05605.12 EMG49127.1 - 0.34 11.2 2.8 1.8 8.9 3.2 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 EMG49127.1 - 0.56 9.9 3.3 20 4.9 0.0 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain FF PF01846.19 EMG49128.1 - 0.00027 21.0 0.9 0.00071 19.7 0.9 1.8 1 0 0 1 1 1 1 FF domain WW PF00397.26 EMG49128.1 - 0.027 14.6 0.6 0.049 13.7 0.6 1.5 1 0 0 1 1 1 0 WW domain ketoacyl-synt PF00109.26 EMG49129.1 - 3.2e-61 207.1 0.4 1.3e-59 201.9 0.0 2.3 2 1 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMG49129.1 - 3e-35 120.8 0.2 4.9e-35 120.1 0.2 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EMG49129.1 - 5.6e-08 32.5 0.3 4.4e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain ADH_zinc_N PF00107.26 EMG49130.1 - 2.9e-10 40.2 0.0 5.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG49130.1 - 8.8e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Mpp10 PF04006.12 EMG49130.1 - 0.00025 19.7 13.4 0.00043 18.9 13.4 1.3 1 0 0 1 1 1 1 Mpp10 protein Cnd2 PF05786.14 EMG49130.1 - 0.0016 17.2 12.9 0.0026 16.5 12.9 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 BUD22 PF09073.10 EMG49130.1 - 0.0019 17.6 10.5 0.0028 17.1 10.5 1.2 1 0 0 1 1 1 1 BUD22 DUF2052 PF09747.9 EMG49130.1 - 0.0026 17.9 10.3 0.0026 17.9 10.3 1.5 2 0 0 2 2 1 1 Coiled-coil domain containing protein (DUF2052) TERB2 PF15101.6 EMG49130.1 - 0.0056 16.8 4.2 0.0056 16.8 4.2 1.6 2 0 0 2 2 1 1 Telomere-associated protein TERB2 SDA1 PF05285.12 EMG49130.1 - 0.0095 15.4 16.2 0.015 14.8 16.2 1.2 1 0 0 1 1 1 1 SDA1 Tim54 PF11711.8 EMG49130.1 - 0.01 14.7 7.7 0.017 13.9 7.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 EMG49130.1 - 0.015 14.3 2.4 0.02 13.9 2.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 EMG49130.1 - 0.018 15.4 10.3 0.018 15.4 10.3 1.5 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 EMG49130.1 - 0.028 14.6 0.5 0.052 13.7 0.5 1.5 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 EMG49130.1 - 0.03 14.8 6.4 0.061 13.8 6.4 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2151 PF10221.9 EMG49130.1 - 0.064 11.9 5.8 0.097 11.2 5.8 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4746 PF15928.5 EMG49130.1 - 0.074 12.5 13.5 0.14 11.6 13.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Eapp_C PF10238.9 EMG49130.1 - 0.075 13.1 4.8 0.58 10.2 5.3 2.0 2 0 0 2 2 2 0 E2F-associated phosphoprotein Nop14 PF04147.12 EMG49130.1 - 0.088 11.0 17.9 0.12 10.6 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF981 PF06168.11 EMG49130.1 - 0.093 12.7 1.3 0.15 12.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF4484 PF14831.6 EMG49130.1 - 0.19 11.7 7.2 0.37 10.8 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) RPN2_C PF18004.1 EMG49130.1 - 0.2 11.6 16.5 0.42 10.5 16.5 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sporozoite_P67 PF05642.11 EMG49130.1 - 0.23 9.5 12.5 0.31 9.1 12.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIF_alpha PF05793.12 EMG49130.1 - 0.3 9.7 23.0 0.45 9.1 23.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Paf1 PF03985.13 EMG49130.1 - 0.51 9.3 18.1 0.9 8.5 18.1 1.3 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 EMG49130.1 - 0.52 9.0 5.9 0.81 8.4 5.9 1.2 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 EMG49130.1 - 0.53 8.3 26.1 0.76 7.8 26.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EMG49130.1 - 0.59 8.3 14.8 0.83 7.9 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 EMG49130.1 - 0.73 9.0 12.0 1.2 8.3 12.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.6 EMG49130.1 - 1 9.0 16.6 0.15 11.7 11.7 2.0 2 0 0 2 2 2 0 FAM176 family TFB6 PF17110.5 EMG49130.1 - 1.3 8.8 11.1 2.4 7.9 11.1 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Myc_N PF01056.18 EMG49130.1 - 1.3 8.8 15.3 2.1 8.1 11.3 2.1 2 0 0 2 2 2 0 Myc amino-terminal region CDC27 PF09507.10 EMG49130.1 - 1.4 8.2 20.1 2.6 7.3 20.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RP-C_C PF11800.8 EMG49130.1 - 1.8 8.6 4.2 3.3 7.8 4.2 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region DDRGK PF09756.9 EMG49130.1 - 1.9 8.1 25.3 0.024 14.2 16.0 2.4 3 0 0 3 3 3 0 DDRGK domain Zip PF02535.22 EMG49130.1 - 2.3 7.4 5.3 4.2 6.5 5.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3464 PF11947.8 EMG49130.1 - 2.4 7.9 6.5 5.2 6.8 6.5 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RAB3GAP2_C PF14656.6 EMG49130.1 - 3.2 5.9 5.7 4.8 5.3 5.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus NPR3 PF03666.13 EMG49130.1 - 3.7 6.2 10.6 6.6 5.4 10.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4820 PF16091.5 EMG49130.1 - 3.8 6.8 10.4 6.7 6.0 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CPSF100_C PF13299.6 EMG49130.1 - 4.8 7.3 11.3 0.44 10.7 6.7 1.6 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal NOA36 PF06524.12 EMG49130.1 - 5.3 6.3 18.1 7.6 5.8 18.1 1.2 1 0 0 1 1 1 0 NOA36 protein PPL5 PF18168.1 EMG49130.1 - 5.4 6.2 7.2 8.7 5.5 7.2 1.3 1 0 0 1 1 1 0 Prim-pol family 5 PI3K_1B_p101 PF10486.9 EMG49130.1 - 8 4.1 10.4 12 3.6 10.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AIM3 PF17096.5 EMG49130.1 - 8.1 7.5 10.3 41 5.2 10.1 2.3 2 0 0 2 2 1 0 Altered inheritance of mitochondria protein 3 CobT PF06213.12 EMG49130.1 - 8.3 5.7 22.0 15 4.9 22.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Connexin PF00029.19 EMG49130.1 - 9 6.0 10.4 17 5.0 10.4 1.4 1 0 0 1 1 1 0 Connexin F-box PF00646.33 EMG49131.1 - 0.015 15.2 4.0 0.15 11.9 4.0 2.6 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 EMG49131.1 - 0.02 14.8 1.4 0.02 14.8 1.4 2.7 2 1 0 2 2 2 0 F-box-like F-box-like_2 PF13013.6 EMG49131.1 - 0.02 14.8 0.1 0.068 13.1 0.1 1.9 1 0 0 1 1 1 0 F-box-like domain LRR_4 PF12799.7 EMG49131.1 - 1.1 9.8 4.1 11 6.6 0.0 4.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Ribosomal_L18 PF17135.4 EMG49132.1 - 2.3e-82 274.9 1.6 2.5e-82 274.8 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EMG49132.1 - 0.072 13.8 0.1 0.25 12.0 0.1 2.0 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Prefoldin PF02996.17 EMG49133.1 - 4.3e-27 94.4 10.2 7.4e-27 93.6 10.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit KxDL PF10241.9 EMG49133.1 - 0.0029 17.8 5.0 0.12 12.7 0.3 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein RF-1 PF00472.20 EMG49133.1 - 0.67 9.9 4.7 0.31 11.0 0.4 2.1 2 0 0 2 2 2 0 RF-1 domain End3 PF12761.7 EMG49133.1 - 1.6 8.9 11.9 15 5.6 11.9 2.0 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 RRM_1 PF00076.22 EMG49134.1 - 3.2e-34 116.6 0.0 4.3e-16 58.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMG49134.1 - 4.1e-12 46.0 0.1 1.1e-06 28.6 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EMG49134.1 - 0.0041 17.1 0.1 2.6 8.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif EF-hand_12 PF17901.1 EMG49134.1 - 0.0057 17.1 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand fold domain RL PF17797.1 EMG49134.1 - 0.0077 16.2 4.2 0.054 13.4 0.0 2.6 3 0 0 3 3 3 1 RL domain TraT PF05818.12 EMG49134.1 - 1.4 8.6 8.3 2.3 7.8 8.3 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein THOC2_N PF16134.5 EMG49134.1 - 1.7 7.2 3.0 3 6.3 3.0 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus ABC_trans_N PF14510.6 EMG49135.1 - 5.9e-22 78.1 0.0 9.1e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC_tran PF00005.27 EMG49135.1 - 4.9e-07 30.3 0.0 9.7e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EMG49135.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase MFS_1 PF07690.16 EMG49136.1 - 4.7e-42 144.2 31.0 8.9e-42 143.3 27.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily APG9 PF04109.16 EMG49137.1 - 1.8e-180 601.1 21.9 2.4e-180 600.6 21.9 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 Nop14 PF04147.12 EMG49138.1 - 2.4e-161 539.0 59.9 2.9e-95 320.3 14.0 3.1 1 1 1 2 2 2 2 Nop14-like family ABC2_membrane PF01061.24 EMG49139.1 - 9.3e-80 267.0 60.0 1.8e-41 141.9 24.1 3.3 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 EMG49139.1 - 7.7e-37 125.1 5.8 7.5e-32 109.1 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 EMG49139.1 - 2.9e-26 92.6 0.0 4.9e-18 66.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EMG49139.1 - 2.3e-05 24.4 0.0 5.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EMG49139.1 - 6e-05 22.7 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMG49139.1 - 0.0003 21.2 0.0 0.00066 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EMG49139.1 - 0.0011 18.8 0.1 0.54 10.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EMG49139.1 - 0.0057 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMG49139.1 - 0.0065 17.0 0.3 0.016 15.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain SMC_N PF02463.19 EMG49139.1 - 0.0074 15.8 0.0 0.17 11.3 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EMG49139.1 - 0.021 14.6 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMG49139.1 - 0.032 14.0 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EMG49139.1 - 0.033 14.5 0.1 0.14 12.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 EMG49139.1 - 0.036 14.6 0.0 0.081 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 EMG49139.1 - 0.039 13.8 0.1 0.11 12.3 0.1 1.8 1 1 0 1 1 1 0 Deoxynucleoside kinase ABC_ATPase PF09818.9 EMG49139.1 - 0.17 10.6 0.1 0.29 9.9 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class NACHT PF05729.12 EMG49139.1 - 0.33 10.9 2.0 3.7 7.5 0.1 2.6 3 0 0 3 3 3 0 NACHT domain DUF5099 PF17025.5 EMG49140.1 - 0.002 18.5 0.0 0.0057 17.1 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5099) Prenyltransf PF01255.19 EMG49140.1 - 0.075 12.6 0.0 0.31 10.5 0.0 2.0 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Sugar_tr PF00083.24 EMG49141.1 - 1.8e-119 399.6 24.9 2.9e-119 398.9 24.9 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG49141.1 - 1.5e-14 53.7 40.2 4.1e-10 39.1 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily IL31 PF15209.6 EMG49141.1 - 0.011 15.5 1.6 0.029 14.2 1.6 1.7 1 0 0 1 1 1 0 Interleukin 31 DUF148 PF02520.17 EMG49141.1 - 0.044 13.9 3.1 0.088 12.9 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 Caf4 PF11615.8 EMG49141.1 - 0.092 12.7 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 CCR4-associated factor 4 Imm3 PF14425.6 EMG49141.1 - 0.18 11.9 0.6 0.37 10.9 0.6 1.5 1 0 0 1 1 1 0 Immunity protein Imm3 SseC PF04888.12 EMG49141.1 - 1.7 8.1 4.8 2.9 7.4 4.8 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Ank_2 PF12796.7 EMG49142.1 - 2.7e-27 95.2 0.6 7.5e-10 39.3 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMG49142.1 - 7.7e-25 87.0 2.4 3.1e-10 40.4 0.1 4.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMG49142.1 - 1.1e-23 83.0 0.3 6.1e-09 36.0 0.0 4.9 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMG49142.1 - 2.4e-19 67.4 0.8 0.002 18.5 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EMG49142.1 - 2.5e-19 68.8 1.5 1.8e-05 25.0 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat DUF3447 PF11929.8 EMG49142.1 - 2.2e-06 27.5 2.0 0.22 11.5 0.1 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) Glyco_transf_88 PF16849.5 EMG49142.1 - 0.028 13.3 0.1 0.071 12.0 0.0 1.7 1 1 0 2 2 2 0 Glycosyltransferase family 88 MARVEL PF01284.23 EMG49143.1 - 7.8e-27 94.1 18.3 9.3e-27 93.8 18.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 EMG49143.1 - 0.0037 17.1 11.8 0.025 14.4 11.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF588) Arf PF00025.21 EMG49144.1 - 6.6e-81 269.9 0.1 7.5e-81 269.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMG49144.1 - 1.6e-14 54.2 0.0 2.1e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EMG49144.1 - 3.4e-14 52.7 0.0 4.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EMG49144.1 - 2.6e-13 49.9 0.0 2.8e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EMG49144.1 - 1.3e-12 47.6 1.0 8.9e-09 35.0 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EMG49144.1 - 1.5e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMG49144.1 - 3.5e-06 27.1 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EMG49144.1 - 0.0034 16.7 0.5 0.007 15.7 0.5 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase UvrD-helicase PF00580.21 EMG49146.1 - 1.7e-59 201.9 3.6 1.7e-59 201.9 3.6 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EMG49146.1 - 8.9e-52 176.6 1.0 1.9e-51 175.5 0.0 2.1 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EMG49146.1 - 4.7e-29 101.6 0.4 5.9e-27 94.8 0.1 3.1 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EMG49146.1 - 8.9e-10 38.2 0.3 0.00093 19.0 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 EMG49146.1 - 0.00013 21.9 0.3 0.00036 20.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EMG49146.1 - 0.002 17.8 0.9 4.3 6.9 0.4 3.3 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 EMG49146.1 - 0.0027 17.5 0.1 0.21 11.3 0.0 2.9 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 EMG49146.1 - 0.012 15.4 1.3 13 5.4 0.1 3.9 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EMG49146.1 - 0.052 13.4 0.0 0.31 10.9 0.0 2.1 1 1 0 1 1 1 0 Helicase FixO PF02433.15 EMG49146.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO CbiA PF01656.23 EMG49146.1 - 0.21 11.7 1.4 0.27 11.3 0.1 1.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rho_GDI PF02115.17 EMG49147.1 - 1e-54 185.3 0.5 1.2e-54 185.0 0.5 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor RNA_pol_Rpb8 PF03870.15 EMG49147.1 - 0.12 12.6 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb8 R3H PF01424.22 EMG49148.1 - 4.4e-05 23.4 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 R3H domain CENP-B_dimeris PF09026.10 EMG49148.1 - 8.3 6.9 15.8 4.5 7.7 8.5 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Ufd2P_core PF10408.9 EMG49149.1 - 2.4e-202 674.0 4.0 2.9e-202 673.6 4.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EMG49149.1 - 1.9e-27 95.2 0.9 5.1e-27 93.9 0.9 1.8 1 0 0 1 1 1 1 U-box domain SSXT PF05030.12 EMG49149.1 - 0.24 11.1 2.2 0.29 10.8 0.5 2.1 2 0 0 2 2 2 0 SSXT protein (N-terminal region) Ribosomal_L29 PF00831.23 EMG49150.1 - 1.9e-15 56.6 4.4 1.9e-15 56.6 4.4 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein DUF2423 PF10338.9 EMG49150.1 - 2.4 8.5 10.0 0.23 11.7 4.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) RRM_1 PF00076.22 EMG49151.1 - 1.9e-56 187.8 0.1 5.7e-21 74.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMG49151.1 - 1.9e-09 37.2 0.0 3.2e-05 23.7 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EMG49151.1 - 1.2e-08 34.6 0.0 0.0044 16.6 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 EMG49151.1 - 0.002 17.8 18.9 0.002 17.8 18.9 3.1 2 1 1 3 3 3 1 Spt20 family Nup35_RRM_2 PF14605.6 EMG49151.1 - 0.0051 16.8 0.0 0.85 9.7 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 EMG49151.1 - 0.01 15.9 0.2 0.28 11.3 0.0 2.8 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 EMG49151.1 - 0.076 13.1 5.7 0.14 12.3 0.1 3.8 4 2 1 5 5 5 0 RNA recognition motif UCH PF00443.29 EMG49152.1 - 2.1e-47 161.8 0.0 3.6e-47 161.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMG49152.1 - 6.1e-08 32.6 2.8 2.9e-06 27.1 2.8 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GST_N_3 PF13417.6 EMG49153.1 - 6.8e-14 52.0 0.0 1.3e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMG49153.1 - 1.9e-11 44.0 0.2 3.3e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMG49153.1 - 2.2e-11 43.9 0.0 4.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMG49153.1 - 7.3e-11 42.3 0.1 4.6e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMG49153.1 - 3.9e-08 33.4 0.5 7.2e-08 32.5 0.5 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMG49153.1 - 7.9e-07 29.0 0.2 1.6e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EMG49153.1 - 0.008 16.0 0.1 0.02 14.7 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.10 EMG49153.1 - 0.032 14.8 0.0 0.074 13.6 0.0 1.7 1 1 0 1 1 1 0 MetRS-N binding domain GST_N_4 PF17172.4 EMG49153.1 - 0.039 14.7 0.0 0.36 11.6 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain SH3_1 PF00018.28 EMG49154.1 - 7.4e-13 47.9 0.1 1.4e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMG49154.1 - 1.4e-09 37.6 0.1 2.7e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMG49154.1 - 3e-08 33.2 0.0 4.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.13 EMG49154.1 - 0.091 13.4 11.5 0.42 11.3 7.3 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Band_7 PF01145.25 EMG49155.1 - 2.2e-21 76.7 4.2 4.7e-21 75.6 4.2 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family M16C_assoc PF08367.11 EMG49156.1 - 7.7e-68 228.3 4.1 1.2e-67 227.7 4.1 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EMG49156.1 - 7.7e-18 65.2 0.2 9.1e-14 51.9 0.0 3.2 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EMG49156.1 - 1.3e-07 31.7 0.2 5.8e-07 29.6 0.1 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) MMS19_N PF14500.6 EMG49156.1 - 0.098 12.2 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II EMP24_GP25L PF01105.24 EMG49157.1 - 4.7e-39 134.2 0.2 6.1e-39 133.8 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 EMG49157.1 - 0.031 12.5 1.4 0.048 11.8 1.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Rad33 PF08730.10 EMG49158.1 - 9.9e-73 243.6 12.5 2.2e-72 242.5 12.5 1.6 1 0 0 1 1 1 1 Rad33 zf-C2H2 PF00096.26 EMG49158.1 - 1.4e-08 34.7 16.1 5.2e-06 26.6 3.0 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMG49158.1 - 2.9e-07 30.6 0.9 2.9e-07 30.6 0.9 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMG49158.1 - 0.00013 22.5 14.0 0.01 16.6 1.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMG49158.1 - 0.0031 17.8 3.0 0.053 13.8 0.3 3.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF5638 PF18688.1 EMG49158.1 - 0.004 17.4 1.4 2.9 8.2 0.0 3.3 2 0 0 2 2 2 2 Family of unknown function (DUF5638) zf-met PF12874.7 EMG49158.1 - 0.0094 16.3 2.9 0.0099 16.2 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EMG49158.1 - 0.07 13.2 10.6 0.17 11.9 1.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Met_10 PF02475.16 EMG49159.1 - 2.9e-08 33.7 0.0 9.4e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Met-10+ like-protein MTS PF05175.14 EMG49159.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 EMG49159.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RecG_N PF17190.4 EMG49159.1 - 0.34 11.7 1.9 0.32 11.8 0.3 1.7 2 0 0 2 2 2 0 RecG N-terminal helical domain Candida_ALS_N PF11766.8 EMG49160.1 - 2.3e-81 272.7 12.2 4e-81 272.0 12.2 1.4 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Candida_ALS PF05792.13 EMG49160.1 - 3.3e-41 139.5 364.2 5e-08 33.4 18.0 18.0 19 0 0 19 19 19 14 Candida agglutinin-like (ALS) Nucleoporin_FG PF13634.6 EMG49160.1 - 0.0056 17.5 35.2 0.52 11.2 4.3 6.5 1 1 6 7 7 7 3 Nucleoporin FG repeat region DUF502 PF04367.13 EMG49160.1 - 0.0068 16.3 28.7 0.058 13.3 0.2 5.5 3 1 3 7 7 7 5 Protein of unknown function (DUF502) zf-Nse PF11789.8 EMG49161.1 - 3.1e-19 68.5 0.1 6.2e-19 67.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EMG49161.1 - 1.4e-05 25.2 0.1 3.2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 EMG49161.1 - 9e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG49161.1 - 0.0015 18.5 0.2 0.003 17.5 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EMG49161.1 - 0.003 17.8 0.1 0.0062 16.8 0.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EMG49161.1 - 0.014 15.7 0.3 0.025 14.9 0.3 1.4 1 0 0 1 1 1 0 Ring finger domain DUF494 PF04361.13 EMG49161.1 - 0.044 13.7 0.3 0.072 13.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Eco57I PF07669.11 EMG49161.1 - 0.088 13.3 0.2 0.2 12.2 0.2 1.6 1 0 0 1 1 1 0 Eco57I restriction-modification methylase zf-C3HC4 PF00097.25 EMG49161.1 - 0.15 12.0 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCR_TM PF02921.14 EMG49161.1 - 0.15 12.6 0.6 4.9 7.7 0.1 2.6 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region Mrpl_C PF18502.1 EMG49161.1 - 0.22 11.8 1.5 0.37 11.1 1.0 1.7 1 1 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain zf-MYND PF01753.18 EMG49162.1 - 2e-08 34.1 17.9 4.1e-08 33.2 17.9 1.6 1 0 0 1 1 1 1 MYND finger Na_trans_assoc PF06512.13 EMG49162.1 - 0.68 10.2 11.1 0.065 13.5 6.1 1.8 2 1 0 2 2 2 0 Sodium ion transport-associated TFIIA PF03153.13 EMG49162.1 - 0.95 9.4 21.2 0.56 10.1 7.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 EMG49162.1 - 2.6 7.3 7.4 4 6.7 7.4 1.3 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 EMG49162.1 - 3.9 7.5 9.7 0.4 10.7 3.5 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 EMG49162.1 - 4.3 5.3 14.9 8 4.4 14.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 EMG49162.1 - 4.4 6.9 6.5 12 5.5 6.5 1.7 1 0 0 1 1 1 0 FAM176 family Mito_carr PF00153.27 EMG49163.1 - 5.2e-57 189.8 4.9 8.6e-19 67.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LapA_dom PF06305.11 EMG49163.1 - 0.15 11.9 0.1 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TRAUB PF08164.12 EMG49164.1 - 3.3e-24 85.2 0.1 3.3e-24 85.2 0.1 3.7 4 1 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EMG49164.1 - 2.9e-21 76.6 5.2 2.9e-21 76.6 5.2 3.6 4 0 0 4 4 4 1 Apoptosis antagonizing transcription factor DUF3685 PF12452.8 EMG49164.1 - 0.24 11.1 1.6 0.6 9.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3685) TFIID-18kDa PF02269.16 EMG49165.1 - 1.4e-36 124.4 1.4 2.2e-35 120.6 0.1 2.8 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 EMG49165.1 - 0.023 14.8 0.1 0.062 13.4 0.1 1.8 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Hydrolase_4 PF12146.8 EMG49166.1 - 1.4e-15 57.2 0.0 8e-11 41.7 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMG49166.1 - 6.5e-11 42.4 0.1 2.1e-06 27.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMG49166.1 - 6.5e-06 25.8 0.0 2.1e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 EMG49166.1 - 5e-05 23.3 0.3 0.68 9.8 0.0 3.1 1 1 2 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.12 EMG49166.1 - 0.00019 20.5 0.3 0.00029 19.9 0.3 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 EMG49166.1 - 0.00058 19.7 0.4 0.6 9.9 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EMG49166.1 - 0.0074 16.9 0.0 0.0095 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 EMG49166.1 - 0.02 14.2 1.0 0.062 12.6 0.0 1.8 1 1 0 2 2 2 0 Secretory lipase Lipase_3 PF01764.25 EMG49166.1 - 0.023 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S15 PF02129.18 EMG49166.1 - 0.046 13.3 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2974 PF11187.8 EMG49166.1 - 0.14 11.7 0.1 0.17 11.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) IF4E PF01652.18 EMG49167.1 - 7.3e-57 191.6 2.2 8.7e-57 191.4 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E KRE1 PF17056.5 EMG49168.1 - 5.7e-25 86.8 13.8 9.5e-25 86.1 13.8 1.3 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 Med2 PF11214.8 EMG49169.1 - 3.7e-34 116.8 1.4 3.7e-34 116.8 1.4 4.8 2 1 1 3 3 3 1 Mediator complex subunit 2 Asp-B-Hydro_N PF05279.11 EMG49169.1 - 7.6 6.5 30.4 2.1 8.4 27.0 1.7 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Rad21_Rec8_N PF04825.13 EMG49170.1 - 5.2e-28 97.4 0.1 1.1e-27 96.4 0.1 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EMG49170.1 - 5.9e-08 31.9 0.0 1.4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein WD40 PF00400.32 EMG49172.1 - 3e-09 37.3 2.1 3.3e-05 24.5 0.1 4.8 4 1 0 4 4 4 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EMG49172.1 - 2e-07 30.5 6.4 2e-07 30.5 6.4 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EMG49172.1 - 0.0019 18.5 3.8 0.0019 18.5 3.8 2.6 1 1 1 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EMG49172.1 - 0.0031 17.8 6.0 0.0031 17.8 6.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EMG49172.1 - 0.28 11.1 6.0 2.5 8.0 6.0 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EMG49172.1 - 1.6 8.6 8.7 2.1 8.3 1.5 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DER1 PF04511.15 EMG49173.1 - 1.5e-24 87.0 11.1 3e-22 79.5 11.2 2.2 1 1 0 1 1 1 1 Der1-like family Mitoc_mL59 PF18126.1 EMG49174.1 - 7.1e-23 81.3 2.8 2.6e-22 79.5 2.8 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 ADH_zinc_N PF00107.26 EMG49175.1 - 7.4e-27 93.9 0.1 1.3e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG49175.1 - 5.9e-26 90.5 0.1 2.2e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EMG49175.1 - 3.6e-08 33.2 0.0 7.1e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EMG49175.1 - 1.6e-05 24.3 0.3 2.7e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EMG49175.1 - 8.9e-05 21.8 0.1 0.0025 17.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 EMG49175.1 - 0.0031 18.6 0.0 0.018 16.1 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.27 EMG49175.1 - 0.0036 17.8 0.8 0.29 11.7 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EMG49175.1 - 0.004 16.7 0.1 0.0062 16.1 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.12 EMG49175.1 - 0.024 15.3 0.1 0.044 14.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain HI0933_like PF03486.14 EMG49175.1 - 0.038 12.7 0.8 0.053 12.2 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EMG49175.1 - 0.048 12.9 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EMG49175.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ATP-synt_DE_N PF02823.16 EMG49176.1 - 1.4e-19 69.8 0.0 2.1e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain RNA_pol_Rpb1_1 PF04997.12 EMG49177.1 - 2.9e-113 378.3 0.0 5.6e-113 377.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EMG49177.1 - 1.7e-110 368.6 0.1 2.8e-110 367.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EMG49177.1 - 4.6e-76 254.7 0.0 1e-75 253.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EMG49177.1 - 5.9e-64 215.4 0.2 1.5e-63 214.1 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 EMG49177.1 - 1.1e-51 174.4 3.8 3.2e-51 172.8 3.8 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 EMG49177.1 - 2.8e-49 167.1 0.0 6.1e-49 166.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EMG49177.1 - 5.7e-38 129.2 0.1 1.5e-37 127.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EMG49177.1 - 5.6e-14 51.7 311.5 0.012 15.9 11.3 15.8 15 1 0 15 15 15 13 RNA polymerase Rpb1 C-terminal repeat SLATT_4 PF18186.1 EMG49177.1 - 0.035 13.8 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 PIF1 PF05970.14 EMG49178.1 - 1.1e-53 182.7 3.6 6.3e-51 173.7 3.6 2.5 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EMG49178.1 - 6.9e-24 84.6 0.0 1.2e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMG49178.1 - 1.5e-09 38.3 0.0 3.7e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EMG49178.1 - 4e-07 29.6 0.0 1.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EMG49178.1 - 0.00011 22.5 0.0 0.00027 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EMG49178.1 - 0.00034 20.2 0.0 0.001 18.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 EMG49178.1 - 0.0051 15.9 0.0 0.0088 15.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.22 EMG49178.1 - 0.016 14.4 0.0 0.037 13.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 EMG49178.1 - 0.023 15.1 0.1 0.048 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 EMG49178.1 - 0.042 13.3 0.6 0.24 10.8 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein Sigma54_activat PF00158.26 EMG49178.1 - 0.07 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Helicase_RecD PF05127.14 EMG49178.1 - 0.084 12.7 0.1 0.47 10.3 0.1 2.3 1 1 0 1 1 1 0 Helicase ABC_tran PF00005.27 EMG49178.1 - 0.19 12.3 2.3 0.36 11.3 0.0 2.5 2 1 1 3 3 3 0 ABC transporter SAICAR_synt PF01259.18 EMG49179.1 - 6.6e-99 330.6 0.1 7.5e-99 330.4 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase BAR PF03114.18 EMG49180.1 - 5.7e-59 199.7 10.1 7.1e-59 199.3 10.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EMG49180.1 - 1.1e-14 53.7 0.0 2e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMG49180.1 - 9.1e-13 47.9 0.1 1.6e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMG49180.1 - 1.5e-07 31.0 0.0 3.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GCV_H PF01597.19 EMG49180.1 - 0.02 14.8 0.2 0.079 12.9 0.1 2.0 2 0 0 2 2 2 0 Glycine cleavage H-protein DegS PF05384.11 EMG49180.1 - 0.31 10.5 9.6 0.65 9.5 9.6 1.4 1 0 0 1 1 1 0 Sensor protein DegS HIG_1_N PF04588.13 EMG49181.1 - 5.6e-06 26.5 3.6 9.9e-06 25.7 0.2 2.5 3 0 0 3 3 3 1 Hypoxia induced protein conserved region DUF4396 PF14342.6 EMG49181.1 - 0.025 14.9 0.1 1.5 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) LapA_dom PF06305.11 EMG49181.1 - 0.027 14.3 1.9 5.7 6.8 0.2 3.4 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Romo1 PF10247.9 EMG49181.1 - 0.092 13.1 0.3 0.88 10.0 0.1 2.2 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Na_Ca_ex PF01699.24 EMG49182.1 - 3.2e-21 75.9 32.3 1.4e-17 64.1 13.4 3.9 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 EMG49182.1 - 5.8e-12 46.1 8.0 5.8e-12 46.1 8.0 4.3 5 0 0 5 5 5 1 Inner membrane component domain CENP-B_dimeris PF09026.10 EMG49182.1 - 4.3 7.8 18.0 7.3 7.1 0.0 3.8 4 0 0 4 4 4 0 Centromere protein B dimerisation domain Pro_isomerase PF00160.21 EMG49183.1 - 8.1e-48 162.7 0.0 1.3e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EMG49183.1 - 2.4e-09 36.6 5.0 4.9e-05 23.1 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EMG49183.1 - 5.1e-08 32.4 5.4 0.00029 20.5 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMG49183.1 - 0.00018 21.4 6.1 0.00044 20.2 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMG49183.1 - 0.00067 19.9 2.4 0.011 16.0 2.3 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMG49183.1 - 0.0094 15.6 1.0 0.5 10.1 0.2 2.5 2 0 0 2 2 2 1 TPR repeat Endopep_inhib PF16800.5 EMG49183.1 - 0.025 14.5 1.0 0.78 9.7 0.3 2.3 2 0 0 2 2 2 0 IseA DL-endopeptidase inhibitor MIT PF04212.18 EMG49183.1 - 0.076 13.1 0.1 0.076 13.1 0.1 2.9 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 EMG49183.1 - 0.11 13.4 2.8 0.14 13.0 0.3 2.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMG49183.1 - 0.11 13.1 0.4 0.11 13.1 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EMG49183.1 - 0.13 12.3 0.3 0.34 11.0 0.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 EMG49183.1 - 0.47 11.0 3.9 1.1 9.8 0.5 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 EMG49184.1 - 4.1e-64 216.5 0.1 4.8e-64 216.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49184.1 - 2.4e-20 72.9 0.0 3.7e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMG49184.1 - 1.6e-06 28.2 0.0 4.9e-06 26.6 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMG49184.1 - 0.0031 17.1 0.3 0.0055 16.3 0.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EMG49184.1 - 0.023 13.5 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase ABC1 PF03109.16 EMG49184.1 - 0.046 13.9 0.2 0.1 12.8 0.2 1.5 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 EMG49184.1 - 0.061 12.7 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LTV PF04180.14 EMG49185.1 - 4.1e-114 382.3 44.3 4.6e-114 382.1 44.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein POT1 PF02765.17 EMG49185.1 - 0.041 13.7 0.4 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 RsbRD_N PF14361.6 EMG49185.1 - 0.14 12.8 3.3 0.19 12.5 0.1 2.4 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain MatE PF01554.18 EMG49186.1 - 1.7e-66 222.9 32.0 5e-38 130.3 11.3 2.8 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EMG49186.1 - 1.4e-06 28.5 8.3 1.4e-06 28.5 8.3 4.6 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain TMEM247 PF15444.6 EMG49186.1 - 0.12 12.3 0.4 0.19 11.8 0.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 PIH1 PF08190.12 EMG49187.1 - 4.9e-24 84.7 0.7 4.9e-24 84.7 0.7 1.6 2 0 0 2 2 2 1 PIH1 N-terminal domain Exo84_C PF16528.5 EMG49187.1 - 0.0021 17.9 0.3 0.0045 16.8 0.3 1.5 1 0 0 1 1 1 1 Exocyst component 84 C-terminal DUF1664 PF07889.12 EMG49187.1 - 0.0039 17.2 0.4 0.0087 16.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF2316 PF10078.9 EMG49187.1 - 0.076 13.3 1.0 0.15 12.3 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Msap1 PF17077.5 EMG49187.1 - 0.09 11.9 1.4 0.14 11.3 1.4 1.2 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 BPL_N PF09825.9 EMG49188.1 - 8.9e-133 443.0 0.0 1.1e-132 442.6 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal UbiA PF01040.18 EMG49188.1 - 1.3e-43 149.1 11.8 1.9e-43 148.6 11.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-ANAPC11 PF12861.7 EMG49188.1 - 5.3e-36 122.6 4.6 1.2e-35 121.5 4.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EMG49188.1 - 4.3e-20 71.7 9.4 8.1e-20 70.9 9.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain BPL_LplA_LipB PF03099.19 EMG49188.1 - 7.8e-19 67.9 0.0 1.7e-18 66.8 0.0 1.6 2 0 0 2 2 1 1 Biotin/lipoate A/B protein ligase family zf-RING_2 PF13639.6 EMG49188.1 - 1.1e-05 25.7 12.4 4.1e-05 23.8 12.4 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMG49188.1 - 0.01 15.7 5.9 0.01 15.7 5.9 2.1 1 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMG49188.1 - 0.022 14.6 10.2 0.056 13.3 10.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_42M PF08532.10 EMG49188.1 - 0.075 12.5 0.1 2.9 7.3 0.1 2.4 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain Pec_lyase_N PF04431.13 EMG49188.1 - 0.17 12.2 0.1 0.37 11.1 0.1 1.5 1 0 0 1 1 1 0 Pectate lyase, N terminus zf-RING_4 PF14570.6 EMG49188.1 - 0.72 9.7 8.2 0.53 10.1 0.6 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EMG49188.1 - 0.85 9.6 6.3 1.7 8.6 6.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 EMG49188.1 - 1.5 8.9 12.5 0.59 10.2 7.0 2.5 2 0 0 2 2 2 0 RING-type zinc-finger RINGv PF12906.7 EMG49188.1 - 4.4 7.5 7.5 8.7 6.6 7.5 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 EMG49188.1 - 4.6 7.5 7.5 11 6.2 7.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EMG49188.1 - 5.6 6.8 7.9 17 5.3 7.9 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 EMG49188.1 - 6.8 6.7 10.6 15 5.7 10.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Alpha-amylase PF00128.24 EMG49189.1 - 8.4e-122 406.9 1.3 2.7e-121 405.3 0.9 2.1 2 0 0 2 2 2 1 Alpha amylase, catalytic domain AA_kinase PF00696.28 EMG49189.1 - 6.7e-31 107.7 0.5 1.3e-30 106.8 0.5 1.4 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EMG49189.1 - 9.1e-15 54.4 0.1 2.6e-14 52.9 0.1 1.9 1 0 0 1 1 1 1 PUA domain Vps39_2 PF10367.9 EMG49189.1 - 0.00026 21.4 0.0 0.00084 19.8 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Malt_amylase_C PF16657.5 EMG49189.1 - 0.017 15.2 0.0 0.053 13.7 0.0 1.8 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 EMG49189.1 - 0.03 13.4 1.4 0.077 12.1 0.0 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain MFS_1 PF07690.16 EMG49190.1 - 8.2e-31 107.2 16.6 8.2e-31 107.2 16.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily GPHR_N PF12537.8 EMG49190.1 - 0.1 12.7 0.5 0.32 11.1 0.1 2.0 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Y_phosphatase PF00102.27 EMG49191.1 - 6.2e-59 199.4 0.1 1.1e-58 198.5 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EMG49191.1 - 4.5e-06 27.1 0.0 2.3e-05 24.8 0.0 2.2 3 0 0 3 3 3 1 Rhodanese-like domain DSPc PF00782.20 EMG49191.1 - 7.5e-05 22.6 0.6 0.00032 20.5 0.6 2.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EMG49191.1 - 0.0021 18.2 0.1 0.0066 16.6 0.1 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EMG49191.1 - 0.044 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family UvrD-helicase PF00580.21 EMG49193.1 - 1.9e-30 106.5 4.5 3.2e-15 56.5 0.0 3.1 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EMG49193.1 - 6.2e-27 94.7 0.0 1.1e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EMG49193.1 - 4.9e-14 52.5 1.7 4.5e-13 49.3 0.2 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EMG49193.1 - 4.5e-09 36.3 0.0 3.8e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EMG49193.1 - 6.8e-06 26.1 0.7 3.1e-05 23.9 0.7 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMG49193.1 - 0.00038 20.7 0.1 0.4 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain YflT PF11181.8 EMG49193.1 - 0.0031 18.0 0.2 0.37 11.3 0.0 2.9 3 0 0 3 3 2 1 Heat induced stress protein YflT DEAD PF00270.29 EMG49193.1 - 0.0064 16.3 0.2 1.7 8.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EMG49193.1 - 0.011 15.7 1.4 0.021 14.8 0.1 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EMG49193.1 - 0.013 14.8 0.6 0.68 9.1 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 EMG49193.1 - 0.029 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 EMG49193.1 - 0.042 13.7 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Helicase DUF4296 PF14129.6 EMG49193.1 - 0.068 13.8 0.2 11 6.7 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) RNA_pol_I_TF PF04090.12 EMG49193.1 - 0.092 12.2 0.5 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase I specific initiation factor Peptidase_C14 PF00656.22 EMG49193.1 - 0.11 12.4 0.5 2.5 8.0 0.0 2.7 4 0 0 4 4 4 0 Caspase domain Vps52 PF04129.12 EMG49194.1 - 1.4e-41 142.8 14.0 3e-40 138.4 14.0 2.0 1 1 0 1 1 1 1 Vps52 / Sac2 family Mating_N PF12731.7 EMG49194.1 - 0.024 14.7 0.8 0.062 13.4 0.8 1.7 1 0 0 1 1 1 0 Mating-type protein beta 1 Laminin_II PF06009.12 EMG49194.1 - 1.2 9.1 6.6 1.4 8.9 1.0 2.4 2 0 0 2 2 2 0 Laminin Domain II APG6_N PF17675.1 EMG49194.1 - 4.7 7.8 11.2 4.2 7.9 2.2 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Rep_fac_C PF08542.11 EMG49195.1 - 4.9e-23 81.4 0.1 3e-22 78.8 0.0 2.3 3 0 0 3 3 3 1 Replication factor C C-terminal domain AAA PF00004.29 EMG49195.1 - 7.3e-12 45.8 0.0 1.4e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EMG49195.1 - 2.1e-11 43.9 0.1 9.7e-10 38.5 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 EMG49195.1 - 2.1e-07 31.0 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMG49195.1 - 2.9e-06 27.8 0.0 0.00031 21.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 EMG49195.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EMG49195.1 - 3.8e-05 23.7 0.0 7.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EMG49195.1 - 3.9e-05 24.0 0.0 0.12 12.7 0.0 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 EMG49195.1 - 8.6e-05 22.3 0.0 0.00025 20.8 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EMG49195.1 - 0.0004 20.2 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 EMG49195.1 - 0.0024 17.3 0.0 0.034 13.5 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 EMG49195.1 - 0.0078 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EMG49195.1 - 0.0083 16.4 0.0 0.027 14.8 0.0 2.0 1 1 0 1 1 1 1 AAA C-terminal domain TniB PF05621.11 EMG49195.1 - 0.022 14.2 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 EMG49195.1 - 0.025 14.9 0.1 0.43 10.9 0.0 2.5 2 1 1 3 3 2 0 AAA domain NTPase_1 PF03266.15 EMG49195.1 - 0.053 13.4 0.0 0.3 11.0 0.0 2.1 1 1 0 2 2 2 0 NTPase MeaB PF03308.16 EMG49195.1 - 0.064 12.2 0.0 0.54 9.2 0.0 2.2 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EMG49195.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EMG49195.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EMG49195.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNase_P_pop3 PF08228.11 EMG49196.1 - 3e-24 85.9 0.0 3.8e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 KH_8 PF17903.1 EMG49197.1 - 8.6e-07 29.0 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EMG49197.1 - 0.05 13.4 0.3 0.13 12.1 0.3 1.7 1 0 0 1 1 1 0 KH domain TRAPP PF04051.16 EMG49198.1 - 2.9e-43 147.1 0.0 3.6e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component eIF3_subunit PF08597.10 EMG49199.1 - 6.5e-60 203.0 25.3 7.4e-60 202.9 25.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF746 PF05344.11 EMG49199.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Lipase_GDSL_3 PF14606.6 EMG49199.1 - 0.31 11.2 0.1 0.31 11.2 0.1 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family NinG PF05766.12 EMG49199.1 - 4.6 7.1 8.5 1.7 8.5 5.5 1.8 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein Vfa1 PF08432.10 EMG49199.1 - 4.9 7.4 14.5 1.5 9.1 11.4 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 EMG49199.1 - 6.5 4.9 12.6 8.1 4.6 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein bPH_4 PF06713.11 EMG49200.1 - 0.058 13.5 0.1 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial PH domain TLE_N PF03920.15 EMG49200.1 - 0.087 12.9 4.7 0.75 9.9 0.2 3.2 3 0 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain Vps54 PF07928.12 EMG49200.1 - 0.19 12.2 0.3 0.43 11.0 0.3 1.5 1 0 0 1 1 1 0 Vps54-like protein Thioredoxin PF00085.20 EMG49201.1 - 7.9e-31 106.1 0.0 8.8e-31 106.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EMG49201.1 - 4.6e-08 33.3 0.2 2.3e-05 24.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EMG49201.1 - 5.9e-06 26.1 0.0 6.4e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMG49201.1 - 7.7e-06 26.3 0.3 6e-05 23.4 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EMG49201.1 - 0.00012 22.0 0.0 0.00015 21.7 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Phosducin PF02114.16 EMG49201.1 - 0.00096 18.2 0.0 0.0011 18.0 0.0 1.0 1 0 0 1 1 1 1 Phosducin AhpC-TSA PF00578.21 EMG49201.1 - 0.0011 18.9 0.0 0.0016 18.4 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 EMG49201.1 - 0.0017 18.6 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Redoxin PF08534.10 EMG49201.1 - 0.0043 16.8 0.2 0.035 13.8 0.1 1.9 1 1 1 2 2 2 1 Redoxin OST3_OST6 PF04756.13 EMG49201.1 - 0.005 16.2 0.0 0.0052 16.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DIM1 PF02966.16 EMG49201.1 - 0.0054 16.5 0.0 0.006 16.4 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_3 PF13192.6 EMG49201.1 - 0.023 14.7 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain HyaE PF07449.11 EMG49201.1 - 0.024 14.6 0.0 0.038 13.9 0.0 1.3 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE PAS_8 PF13188.7 EMG49201.1 - 0.056 13.5 0.0 11 6.2 0.0 2.2 2 0 0 2 2 2 0 PAS domain Lipase_GDSL_2 PF13472.6 EMG49202.1 - 3.1e-25 89.6 0.0 4e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMG49202.1 - 2.7e-17 63.4 0.2 4.3e-17 62.7 0.2 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AP_endonuc_2 PF01261.24 EMG49202.1 - 0.026 13.9 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF4141 PF13605.6 EMG49202.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) DsrH PF04077.12 EMG49202.1 - 0.18 12.0 0.1 0.52 10.5 0.0 1.8 2 0 0 2 2 2 0 DsrH like protein zf-LYAR PF08790.11 EMG49203.1 - 1.1e-14 53.9 6.9 1.1e-14 53.9 6.9 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 EMG49203.1 - 0.035 13.7 1.1 3.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Nup96 PF12110.8 EMG49203.1 - 0.049 12.8 1.1 0.057 12.5 1.1 1.1 1 0 0 1 1 1 0 Nuclear protein 96 zf-C2H2_3rep PF18868.1 EMG49203.1 - 0.17 12.6 4.6 0.25 12.0 4.1 1.6 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 EMG49203.1 - 0.99 10.4 6.5 14 6.8 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Neur_chan_memb PF02932.16 EMG49203.1 - 2.2 8.3 5.3 2.3 8.2 5.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RabGAP-TBC PF00566.18 EMG49203.1 - 2.5 7.7 6.9 3.6 7.2 6.9 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Ndc1_Nup PF09531.10 EMG49203.1 - 3.4 6.3 6.7 3.9 6.0 6.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Csm1 PF12539.8 EMG49204.1 - 3.4e-20 72.5 1.3 4.4e-20 72.1 0.3 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 PWI PF01480.17 EMG49204.1 - 0.23 11.8 2.1 8.7 6.7 1.0 2.4 2 0 0 2 2 2 0 PWI domain IKKbetaNEMObind PF12179.8 EMG49204.1 - 0.39 10.8 3.1 0.91 9.6 3.1 1.7 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain dCache_2 PF08269.11 EMG49204.1 - 1.9 7.6 7.6 4.5 6.4 7.6 1.6 1 1 0 1 1 1 0 Cache domain Ecm29 PF13001.7 EMG49205.1 - 0.0037 16.0 1.4 0.0039 15.9 1.4 1.1 1 0 0 1 1 1 1 Proteasome stabiliser ATG16 PF08614.11 EMG49205.1 - 0.051 13.8 13.1 0.06 13.6 13.1 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Gastrin PF00918.17 EMG49205.1 - 0.086 13.8 3.6 0.099 13.6 3.6 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family SPX PF03105.19 EMG49205.1 - 0.11 12.4 12.1 0.14 12.1 12.1 1.0 1 0 0 1 1 1 0 SPX domain Prominin PF05478.11 EMG49205.1 - 0.19 9.7 5.7 0.2 9.6 5.7 1.0 1 0 0 1 1 1 0 Prominin eIF3_N PF09440.10 EMG49205.1 - 0.21 12.1 5.9 0.33 11.4 5.9 1.4 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain DUF737 PF05300.11 EMG49205.1 - 0.24 11.7 11.2 0.27 11.6 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) REC114-like PF15165.6 EMG49205.1 - 0.47 10.2 5.8 0.54 10.0 5.8 1.1 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like PAF-AH_p_II PF03403.13 EMG49205.1 - 0.57 8.6 4.2 0.7 8.3 4.2 1.0 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II ARD PF03079.14 EMG49205.1 - 0.63 10.2 5.0 0.79 9.9 5.0 1.1 1 0 0 1 1 1 0 ARD/ARD' family DNA_pol_delta_4 PF04081.13 EMG49205.1 - 0.84 10.0 7.2 1.1 9.7 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase delta, subunit 4 DUF3408 PF11888.8 EMG49205.1 - 1 9.5 12.3 2.6 8.2 12.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) DUF908 PF06012.12 EMG49205.1 - 2.1 7.7 13.6 2.4 7.5 13.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) NAD_binding_5 PF07994.12 EMG49206.1 - 2.6e-143 477.3 0.0 2.9e-143 477.1 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EMG49206.1 - 1.4e-45 154.1 0.3 2.9e-45 153.0 0.3 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Glyco_hydro_18 PF00704.28 EMG49208.1 - 3.2e-27 96.1 9.1 1e-25 91.2 9.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Cnd1 PF12717.7 EMG49209.1 - 0.038 14.0 0.5 0.069 13.2 0.5 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Molybdopterin PF00384.22 EMG49210.1 - 5.6e-72 243.1 0.0 4.9e-69 233.4 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EMG49210.1 - 6.1e-20 71.1 0.7 1.7e-19 69.7 0.7 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 EMG49210.1 - 1.4e-17 64.1 0.0 3.7e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EMG49210.1 - 4.4e-15 54.9 0.5 4.4e-15 54.9 0.5 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EMG49210.1 - 4.4e-08 33.0 0.3 4.4e-08 33.0 0.3 2.2 1 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EMG49210.1 - 0.0036 17.1 0.1 0.074 12.8 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Lyx_isomer PF07385.12 EMG49210.1 - 0.022 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 D-lyxose isomerase Fer4 PF00037.27 EMG49210.1 - 0.11 12.4 1.1 3.3 7.7 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 EMG49210.1 - 0.34 11.0 2.3 5.5 7.2 2.3 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_4 PF12800.7 EMG49210.1 - 8.4 7.2 6.5 1.5 9.6 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Zn_clus PF00172.18 EMG49211.1 - 4.8e-06 26.6 6.2 1e-05 25.6 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-PHD-like PF15446.6 EMG49211.1 - 0.018 14.7 1.8 0.038 13.6 1.8 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DUF382 PF04037.13 EMG49212.1 - 1e-48 164.7 1.1 1e-48 164.7 1.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EMG49212.1 - 2.8e-18 65.5 0.2 4.9e-18 64.7 0.2 1.4 1 0 0 1 1 1 1 PSP His_Phos_1 PF00300.22 EMG49215.1 - 2e-11 44.0 0.0 4.1e-11 42.9 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CENP-X PF09415.10 EMG49216.1 - 3.3e-22 78.6 0.3 4.3e-16 59.0 0.3 2.5 2 1 0 2 2 2 2 CENP-S associating Centromere protein X Asparaginase PF00710.20 EMG49217.1 - 4.2e-57 192.8 0.1 1.9e-56 190.6 0.0 1.9 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EMG49217.1 - 1.4e-19 70.4 0.0 9.8e-19 67.7 0.1 2.1 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain AMP-binding PF00501.28 EMG49218.1 - 3e-84 283.1 0.0 4.7e-84 282.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMG49218.1 - 0.14 13.2 0.0 0.36 11.8 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain PAP_central PF04928.17 EMG49218.1 - 1.3 7.9 3.4 8.5 5.3 0.0 2.7 2 1 1 3 3 3 0 Poly(A) polymerase central domain Proteasome PF00227.26 EMG49219.1 - 5.2e-48 163.1 0.1 8e-48 162.4 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EMG49219.1 - 9.1e-11 41.0 0.0 9.1e-11 41.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal TRAPPC9-Trs120 PF08626.11 EMG49220.1 - 0 1103.7 17.6 0 1103.5 17.6 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 EMG49220.1 - 0.0093 16.2 0.1 0.033 14.5 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 EMG49220.1 - 0.038 13.0 0.1 0.071 12.1 0.1 1.4 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit COX6B PF02297.17 EMG49221.1 - 5.1e-21 74.7 6.6 6e-21 74.5 6.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EMG49221.1 - 0.61 10.4 4.4 11 6.4 4.4 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Aha1_N PF09229.11 EMG49222.1 - 9.9e-36 123.0 0.0 1.7e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EMG49222.1 - 1.3e-15 57.7 0.0 2.8e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein FtsJ PF01728.19 EMG49223.1 - 9.2e-47 159.4 0.0 1.1e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase ADH_N PF08240.12 EMG49224.1 - 2.2e-24 85.5 3.6 2.2e-24 85.5 3.6 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMG49224.1 - 5.4e-20 71.7 0.7 1.6e-19 70.2 0.3 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMG49224.1 - 0.004 16.7 0.2 0.027 14.0 0.2 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EMG49224.1 - 0.0048 16.2 0.4 0.0085 15.4 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMG49224.1 - 0.0053 16.4 0.1 0.0094 15.5 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 EMG49224.1 - 0.021 15.1 0.1 0.044 14.0 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain IGFBP PF00219.18 EMG49224.1 - 0.023 15.3 0.5 0.08 13.6 0.5 1.9 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Imm70 PF15601.6 EMG49224.1 - 0.039 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 70 DAO PF01266.24 EMG49224.1 - 0.066 12.8 0.4 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ADH_zinc_N_2 PF13602.6 EMG49224.1 - 0.093 13.8 0.0 0.16 13.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 EMG49224.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2249 PF10006.9 EMG49224.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Utp12 PF04003.12 EMG49225.1 - 2e-20 73.1 0.9 2e-20 73.1 0.9 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family RAB3GAP2_N PF14655.6 EMG49225.1 - 0.0024 17.2 1.1 0.0039 16.5 0.1 1.8 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus ANAPC4_WD40 PF12894.7 EMG49225.1 - 0.018 15.3 0.2 0.15 12.4 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cwf_Cwc_15 PF04889.12 EMG49225.1 - 9.1 5.9 19.8 1.1 9.0 3.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Chordopox_A15 PF05846.12 EMG49226.1 - 0.031 14.5 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A15 protein FSAP_sig_propep PF03032.15 EMG49226.1 - 0.6 10.2 5.1 1.6 8.9 5.1 1.7 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide NOA36 PF06524.12 EMG49226.1 - 9.2 5.5 10.1 16 4.7 10.1 1.4 1 0 0 1 1 1 0 NOA36 protein MAPEG PF01124.18 EMG49227.1 - 0.094 12.6 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 MAPEG family DUF1180 PF06679.12 EMG49228.1 - 6.2 7.2 6.6 7.6 6.9 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Gemin6 PF06372.12 EMG49229.1 - 0.00032 20.3 1.5 9 5.8 0.0 4.0 1 1 3 4 4 4 1 Gemin6 protein EspB_PE PF18625.1 EMG49229.1 - 0.075 13.5 2.3 98 3.5 0.0 4.3 5 0 0 5 5 5 0 ESX-1 secreted protein B PE domain VPS13_C PF16909.5 EMG49229.1 - 0.093 12.5 0.6 7.3 6.3 0.0 2.7 1 1 2 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal CCD PF07860.11 EMG49229.1 - 1.7 8.7 7.5 14 5.7 0.0 3.5 1 1 3 4 4 4 0 WisP family C-Terminal Region TrbC PF04956.13 EMG49229.1 - 9.4 6.5 10.1 39 4.5 0.2 4.6 2 1 1 5 5 5 0 TrbC/VIRB2 family DraK_HK_N PF18092.1 EMG49231.1 - 2.1 8.8 9.0 0.13 12.7 2.4 2.4 2 1 1 3 3 3 0 DraK Histidine Kinase N-terminal domain Utp14 PF04615.13 EMG49232.1 - 4.1e-198 660.6 72.8 4.1e-198 660.6 72.8 2.1 1 1 1 2 2 2 1 Utp14 protein ALO PF04030.14 EMG49233.1 - 1.3e-107 359.5 0.8 1.6e-107 359.2 0.2 1.4 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EMG49233.1 - 1e-20 73.9 0.0 1.9e-20 73.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SIS_2 PF13580.6 EMG49233.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 SIS domain MFS_1 PF07690.16 EMG49234.1 - 1.3e-44 152.6 42.3 2.3e-43 148.5 42.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMG49234.1 - 4.3e-14 51.9 23.3 5.8e-14 51.4 23.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMG49234.1 - 5.1e-11 42.1 9.1 5.1e-11 42.1 9.1 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2691 PF10903.8 EMG49234.1 - 0.09 12.6 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) AAA PF00004.29 EMG49235.1 - 8.4e-38 129.8 0.0 1.8e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EMG49235.1 - 3.5e-08 33.3 0.1 6e-07 29.4 0.0 3.1 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EMG49235.1 - 8.6e-07 28.8 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EMG49235.1 - 2.8e-06 27.0 0.0 5.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EMG49235.1 - 0.0001 22.6 0.9 0.0055 17.0 0.1 2.7 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 EMG49235.1 - 0.00035 21.0 0.2 0.0017 18.7 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EMG49235.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EMG49235.1 - 0.0016 18.4 0.1 0.0059 16.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EMG49235.1 - 0.003 16.8 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EMG49235.1 - 0.0044 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMG49235.1 - 0.0048 16.7 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EMG49235.1 - 0.0055 16.1 0.1 0.01 15.3 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EMG49235.1 - 0.0063 17.1 0.0 0.022 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EMG49235.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EMG49235.1 - 0.014 15.0 0.0 0.035 13.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EMG49235.1 - 0.016 14.9 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMG49235.1 - 0.017 15.3 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EMG49235.1 - 0.04 13.3 0.5 2.5 7.4 0.1 2.3 1 1 1 2 2 2 0 KaiC TniB PF05621.11 EMG49235.1 - 0.042 13.3 0.0 4.2 6.7 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 EMG49235.1 - 0.077 12.7 0.0 0.17 11.6 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 EMG49235.1 - 0.08 12.8 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EMG49235.1 - 0.09 12.8 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EMG49235.1 - 0.096 13.1 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EMG49235.1 - 0.1 13.1 0.3 0.34 11.4 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_7 PF12775.7 EMG49235.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EMG49235.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 EMG49235.1 - 0.19 11.9 0.3 0.35 11.1 0.3 1.4 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.8 EMG49236.1 - 0.024 14.6 8.9 0.024 14.6 8.9 4.4 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.6 EMG49236.1 - 0.087 12.9 25.6 0.32 11.1 10.2 3.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 GAS PF13851.6 EMG49236.1 - 0.13 11.6 39.2 0.48 9.7 37.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_lysis PF03245.13 EMG49236.1 - 0.4 10.8 14.8 3.1 8.0 6.2 2.9 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein TPR_MLP1_2 PF07926.12 EMG49236.1 - 0.91 9.6 33.6 0.25 11.4 27.0 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Myb_DNA-bind_6 PF13921.6 EMG49238.1 - 6.8e-11 42.3 0.2 2e-10 40.8 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMG49238.1 - 3.9e-10 39.8 0.4 6.9e-10 39.0 0.4 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain TAP42 PF04177.12 EMG49239.1 - 1.5 7.9 9.5 1.5 7.8 9.5 1.0 1 0 0 1 1 1 0 TAP42-like family DUF4611 PF15387.6 EMG49239.1 - 5.9 7.2 12.9 7.1 6.9 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) AA_permease PF00324.21 EMG49240.1 - 5.5e-118 394.6 36.9 7.2e-118 394.2 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG49240.1 - 6.7e-30 104.3 39.5 9.3e-30 103.8 39.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG49241.1 - 3.3e-113 378.8 35.0 3.8e-113 378.6 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG49241.1 - 1.7e-29 102.9 36.3 2.3e-29 102.5 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease DNA_pol_E_B PF04042.16 EMG49242.1 - 5.2e-36 124.0 1.2 8.6e-36 123.3 1.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B B_lectin PF01453.24 EMG49242.1 - 0.09 13.3 0.2 1.1 9.9 0.1 2.5 2 1 0 2 2 2 0 D-mannose binding lectin Prenyltrans PF00432.21 EMG49243.1 - 1.1e-58 194.5 1.8 8.3e-12 44.6 0.0 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EMG49243.1 - 0.00088 18.5 0.0 3.8 6.5 0.0 3.6 1 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EMG49243.1 - 0.0015 17.7 0.0 0.44 9.6 0.0 2.6 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain NAD_binding_1 PF00175.21 EMG49246.1 - 3.4e-06 27.7 0.0 4.1e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EMG49246.1 - 4.5e-06 26.9 0.0 7.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 EMG49246.1 - 0.00087 19.8 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Globin Bromodomain PF00439.25 EMG49247.1 - 8.7e-17 61.0 0.7 3.7e-16 59.0 0.2 2.4 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 EMG49247.1 - 1.9e-06 27.8 0.1 5.1e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 EMG49247.1 - 0.0002 21.5 0.2 0.00089 19.4 0.2 2.2 1 0 0 1 1 1 1 Histone-fold protein DUF575 PF04746.12 EMG49247.1 - 0.62 10.3 1.9 4.9 7.5 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF575) UQ_con PF00179.26 EMG49248.1 - 1.5e-51 173.8 0.0 1.6e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMG49248.1 - 0.0019 17.9 0.0 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMG49248.1 - 0.0027 18.0 0.0 0.004 17.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EMG49248.1 - 0.029 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain Fungal_trans_2 PF11951.8 EMG49249.1 - 4.9e-83 279.1 0.8 4.9e-83 279.1 0.8 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG49249.1 - 4.8e-07 29.8 10.3 9.8e-07 28.8 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop PF01798.18 EMG49250.1 - 3.3e-88 295.0 0.2 3.3e-88 295.0 0.2 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EMG49250.1 - 3.2e-06 27.4 0.1 3.2e-06 27.4 0.1 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF2052 PF09747.9 EMG49250.1 - 0.16 12.1 18.1 0.23 11.6 18.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GAGA_bind PF06217.12 EMG49250.1 - 0.19 12.0 15.6 0.32 11.2 15.6 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family CCDC71L PF15374.6 EMG49250.1 - 0.5 9.6 17.4 0.71 9.1 17.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L RNA_polI_A34 PF08208.11 EMG49250.1 - 0.57 10.3 46.1 1.1 9.3 46.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 EMG49250.1 - 0.7 9.7 24.1 1.2 9.0 24.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EMG49250.1 - 1.5 7.0 24.1 2 6.6 24.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EMG49250.1 - 4 5.9 12.0 5.6 5.4 12.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DDHD PF02862.17 EMG49250.1 - 9.9 6.3 8.9 17 5.5 8.9 1.5 1 0 0 1 1 1 0 DDHD domain Perilipin PF03036.16 EMG49251.1 - 0.0006 18.9 0.1 0.00085 18.4 0.1 1.2 1 0 0 1 1 1 1 Perilipin family DUF2841 PF11001.8 EMG49252.1 - 8.1e-27 93.7 1.8 1.9e-26 92.5 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) EIN3 PF04873.13 EMG49252.1 - 2.5 7.3 9.1 1 8.6 4.5 2.3 2 1 0 2 2 2 0 Ethylene insensitive 3 Calpain_III PF01067.22 EMG49253.1 - 0.055 13.7 0.2 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Calpain large subunit, domain III DUF3784 PF12650.7 EMG49253.1 - 0.055 13.7 0.1 0.093 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) RCC1 PF00415.18 EMG49254.1 - 6e-17 62.0 0.1 0.00033 21.2 0.0 4.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMG49254.1 - 1.7e-15 56.3 0.3 1.5e-07 31.0 0.1 4.1 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EMG49254.1 - 7.7e-08 32.5 1.0 0.0041 17.3 0.1 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.7 EMG49254.1 - 4.7e-05 23.9 0.2 0.00038 21.0 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMG49254.1 - 0.0014 19.2 1.4 0.06 13.9 0.3 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DNA_binding_1 PF01035.20 EMG49255.1 - 6e-12 45.5 0.0 4e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain PRKCSH PF07915.13 EMG49257.1 - 1.4e-09 38.8 0.6 2.3e-09 38.1 0.6 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein zf-Mss51 PF13824.6 EMG49258.1 - 2.4e-18 66.0 0.8 5.3e-18 64.9 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.11 EMG49258.1 - 0.1 12.4 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain DUF3784 PF12650.7 EMG49259.1 - 0.059 13.6 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) FAD_binding_6 PF00970.24 EMG49260.1 - 1.2e-07 32.0 0.0 2.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 EMG49260.1 - 7.4e-07 29.7 0.0 2e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Globin NAD_binding_1 PF00175.21 EMG49260.1 - 1.7e-05 25.4 0.0 3.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Coatomer_b_Cpla PF14806.6 EMG49260.1 - 0.084 12.9 0.0 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform CDC45 PF02724.14 EMG49262.1 - 7.4 4.7 12.0 7.3 4.7 12.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 EMG49262.1 - 8.3 6.1 10.7 8.4 6.1 10.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NUDIX PF00293.28 EMG49263.1 - 9.1e-07 29.0 0.0 2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Brix PF04427.18 EMG49264.1 - 9.8e-47 159.6 3.7 1.7e-46 158.8 3.7 1.3 1 0 0 1 1 1 1 Brix domain GTP_EFTU_D2 PF03144.25 EMG49264.1 - 0.061 13.7 0.1 0.32 11.4 0.1 2.3 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DEAD PF00270.29 EMG49265.1 - 6e-50 169.4 0.1 2.5e-49 167.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG49265.1 - 1.6e-31 108.9 0.4 4.8e-31 107.4 0.2 1.9 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG49265.1 - 1.6e-06 28.2 0.0 4.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EMG49265.1 - 1.4e-05 24.4 0.1 1.4e-05 24.4 0.1 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 EMG49265.1 - 0.0023 17.7 0.0 0.0078 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain FYVE PF01363.21 EMG49266.1 - 2.1e-20 72.6 6.1 2.1e-20 72.6 6.1 3.0 3 1 1 4 4 4 1 FYVE zinc finger zf-RING_2 PF13639.6 EMG49266.1 - 6.5e-09 36.0 2.4 6.5e-09 36.0 2.4 4.1 5 0 0 5 5 5 2 Ring finger domain zf-RING_11 PF17123.5 EMG49266.1 - 3.4e-07 29.9 5.7 6.6e-07 29.0 3.2 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EMG49266.1 - 0.00015 21.5 2.3 0.00015 21.5 2.3 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMG49266.1 - 0.00065 19.5 1.4 0.00065 19.5 1.4 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EMG49266.1 - 0.001 18.7 2.4 0.001 18.7 2.4 3.7 4 1 0 4 4 4 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 EMG49266.1 - 0.014 15.6 3.3 0.014 15.6 3.3 4.2 3 2 1 4 4 4 0 RING-H2 zinc finger domain FYVE_2 PF02318.16 EMG49266.1 - 0.31 11.3 21.5 0.036 14.3 10.3 3.6 3 2 0 3 3 3 0 FYVE-type zinc finger zf-piccolo PF05715.13 EMG49266.1 - 2.3 8.4 15.6 4 7.7 0.1 3.9 4 0 0 4 4 4 0 Piccolo Zn-finger Zip PF02535.22 EMG49266.1 - 4.5 6.4 7.8 5.4 6.1 7.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Med21 PF11221.8 EMG49267.1 - 3.6e-49 166.7 22.5 4.2e-47 160.0 22.5 2.0 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 EMG49267.1 - 0.0022 18.0 2.7 0.0022 18.0 2.7 3.0 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 TFIIA PF03153.13 EMG49267.1 - 0.1 12.6 14.0 0.11 12.4 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YjeF_N PF03853.15 EMG49267.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Spt20 PF12090.8 EMG49267.1 - 0.28 10.7 17.7 0.45 10.1 17.7 1.4 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 EMG49267.1 - 0.59 8.8 4.1 0.63 8.7 4.1 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EMG49267.1 - 0.61 8.7 4.4 0.63 8.7 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM76 PF16046.5 EMG49267.1 - 0.66 9.3 4.7 0.84 8.9 4.7 1.2 1 0 0 1 1 1 0 FAM76 protein PMT PF02366.18 EMG49268.1 - 1e-54 185.7 12.5 1e-54 185.7 12.5 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EMG49268.1 - 4.3e-49 166.8 19.5 4.3e-49 166.8 19.5 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EMG49268.1 - 5.2e-21 75.3 0.8 9e-21 74.6 0.8 1.4 1 0 0 1 1 1 1 MIR domain Mucin_bdg PF03272.13 EMG49268.1 - 0.017 15.1 1.2 1.7 8.7 0.1 2.3 1 1 1 2 2 2 0 Putative mucin or carbohydrate-binding module Ins145_P3_rec PF08709.11 EMG49268.1 - 0.02 14.1 0.1 0.038 13.2 0.1 1.4 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor LRR_4 PF12799.7 EMG49269.1 - 1.5e-10 41.1 59.3 0.00022 21.6 3.8 10.0 4 3 3 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG49269.1 - 2.2e-09 36.9 47.4 1e-07 31.6 9.1 6.9 8 1 0 9 9 9 4 Leucine rich repeat LRR_6 PF13516.6 EMG49269.1 - 1.5e-07 30.9 17.4 1.6 9.0 0.0 8.5 8 0 0 8 8 8 3 Leucine Rich repeat Exonuc_VIII PF06630.11 EMG49269.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII TMA7 PF09072.10 EMG49270.1 - 1.1e-25 90.3 18.3 1.1e-25 90.2 18.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 WH1 PF00568.23 EMG49271.1 - 4.7e-31 107.0 0.0 6.6e-31 106.5 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EMG49271.1 - 5.4e-07 29.2 1.5 1.2e-06 28.1 1.5 1.6 1 0 0 1 1 1 1 WH2 motif GCIP PF13324.6 EMG49272.1 - 5e-25 88.6 0.5 7.7e-25 88.0 0.5 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Esterase PF00756.20 EMG49273.1 - 1.2e-50 172.6 0.0 1.4e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 EMG49273.1 - 1.7e-05 23.9 0.0 2.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EMG49273.1 - 0.0083 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EMG49273.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 EMG49273.1 - 0.097 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PLA2_B PF01735.18 EMG49274.1 - 1.5e-202 673.4 7.9 1.9e-202 673.1 7.9 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain TssR PF17643.1 EMG49274.1 - 0.019 13.0 0.0 0.031 12.3 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssR IBR PF01485.21 EMG49274.1 - 0.056 13.7 1.9 0.11 12.8 1.9 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain MFS_1 PF07690.16 EMG49275.1 - 1.4e-31 109.7 39.9 5.8e-27 94.5 19.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG49275.1 - 5.6e-22 78.2 16.0 1.4e-21 76.9 16.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter PRELI PF04707.14 EMG49276.1 - 3.9e-42 143.7 0.1 4.5e-42 143.5 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family COQ9 PF08511.11 EMG49277.1 - 3.6e-28 97.1 0.1 7e-28 96.2 0.1 1.4 1 0 0 1 1 1 1 COQ9 Chordopox_A33R PF05966.12 EMG49278.1 - 0.043 13.1 0.9 0.055 12.8 0.9 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Troponin-I_N PF11636.8 EMG49278.1 - 0.045 13.7 0.3 0.088 12.8 0.3 1.5 1 0 0 1 1 1 0 Troponin I residues 1-32 POC1 PF10450.9 EMG49279.1 - 3.9e-07 29.3 2.0 1.3e-06 27.6 2.0 2.0 1 1 0 1 1 1 1 POC1 chaperone Baculo_19 PF04798.12 EMG49279.1 - 0.018 14.8 0.1 0.083 12.6 0.2 1.8 2 0 0 2 2 2 0 Baculovirus 19 kDa protein conserved region NADH_u_ox_C PF12853.7 EMG49281.1 - 4.1e-42 142.1 0.8 6e-42 141.5 0.8 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 EMG49281.1 - 7.1e-31 106.7 0.0 1e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Polysacc_synt_4 PF04669.13 EMG49282.1 - 2.1e-20 73.1 1.9 9.4e-19 67.7 1.9 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Striatin PF08232.12 EMG49283.1 - 5.4e-08 33.6 28.5 5.4e-08 33.6 28.5 4.9 3 1 0 3 3 3 1 Striatin family DUF3657 PF12394.8 EMG49283.1 - 5.2 7.7 11.5 1.8 9.2 1.0 4.1 3 0 0 3 3 3 0 Protein FAM135 Flg_new PF09479.10 EMG49283.1 - 8.3 6.7 11.8 0.42 10.8 4.5 2.7 3 0 0 3 3 3 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) 2OG-FeII_Oxy PF03171.20 EMG49284.1 - 5.8e-07 29.9 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EMG49284.1 - 0.044 14.5 0.0 0.084 13.6 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal WD40 PF00400.32 EMG49285.1 - 1.1e-18 67.2 9.7 0.00044 21.0 0.4 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG49285.1 - 3.6e-09 36.8 0.2 0.075 13.3 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EMG49285.1 - 0.0096 14.9 0.1 0.11 11.4 0.0 2.2 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain PRP4 PF08799.11 EMG49285.1 - 0.015 14.9 1.6 0.094 12.3 0.1 2.3 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like HDA2-3 PF11496.8 EMG49286.1 - 2e-105 352.2 4.2 2e-105 352.2 4.2 2.2 2 1 1 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Ribosomal_L17 PF01196.19 EMG49286.1 - 0.03 15.2 0.6 0.099 13.5 0.6 1.9 1 0 0 1 1 1 0 Ribosomal protein L17 BLUF PF04940.12 EMG49286.1 - 0.078 13.1 4.6 0.052 13.7 1.6 2.3 2 0 0 2 2 2 0 Sensors of blue-light using FAD DUF573 PF04504.14 EMG49286.1 - 1.7 9.4 9.3 0.3 11.7 4.3 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF573 ETF PF01012.21 EMG49287.1 - 6e-40 137.1 0.2 8.4e-40 136.6 0.2 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ThiF PF00899.21 EMG49287.1 - 1.1e-13 51.2 0.0 1.8e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family PRK PF00485.18 EMG49287.1 - 0.0039 16.9 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 EMG49287.1 - 0.0043 16.4 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Torsin PF06309.11 EMG49287.1 - 0.0058 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Torsin RNA_helicase PF00910.22 EMG49287.1 - 0.006 17.0 0.2 0.04 14.3 0.1 2.3 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 EMG49287.1 - 0.0063 16.5 0.2 0.024 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 EMG49287.1 - 0.007 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain Shikimate_DH PF01488.20 EMG49287.1 - 0.013 15.6 0.0 0.075 13.1 0.0 2.2 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase MobB PF03205.14 EMG49287.1 - 0.014 15.3 0.2 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 EMG49287.1 - 0.048 14.0 0.0 0.097 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EMG49287.1 - 0.06 13.9 0.1 0.25 11.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EMG49287.1 - 0.079 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein cobW PF02492.19 EMG49287.1 - 0.086 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain HEAT PF02985.22 EMG49288.1 - 0.022 15.0 0.0 4 7.9 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat UPF0242 PF06785.11 EMG49288.1 - 0.072 13.2 13.4 0.21 11.7 13.4 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cnd1 PF12717.7 EMG49288.1 - 0.08 13.0 0.2 0.08 13.0 0.2 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Herpes_UL6 PF01763.16 EMG49288.1 - 0.091 11.3 7.4 0.19 10.2 7.4 1.5 1 0 0 1 1 1 0 Herpesvirus UL6 like Asp1 PF16993.5 EMG49288.1 - 0.094 11.9 9.1 0.19 10.9 9.1 1.4 1 0 0 1 1 1 0 Accessory Sec system protein Asp1 Atg14 PF10186.9 EMG49288.1 - 0.096 11.8 11.9 0.22 10.6 11.9 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EMG49288.1 - 0.34 10.1 13.7 1.9 7.7 14.8 1.7 2 0 0 2 2 2 0 TMPIT-like protein TAN PF11640.8 EMG49288.1 - 0.56 10.3 0.0 0.56 10.3 0.0 2.6 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair ADIP PF11559.8 EMG49288.1 - 0.8 9.8 20.5 0.18 11.9 15.9 2.2 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 EMG49288.1 - 2.2 8.7 17.3 0.9 9.9 0.7 4.0 1 1 2 3 3 3 0 TSC-22/dip/bun family Fib_alpha PF08702.10 EMG49288.1 - 3.1 8.0 21.5 1.1 9.4 16.7 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 EMG49288.1 - 5.5 6.2 14.9 14 4.9 14.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 EMG49288.1 - 9.9 3.9 11.9 17 3.1 11.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SCO1-SenC PF02630.14 EMG49289.1 - 2.5e-43 147.2 0.0 3.6e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EMG49289.1 - 0.0055 16.6 0.0 0.025 14.5 0.0 2.0 1 1 1 2 2 2 1 AhpC/TSA family SET PF00856.28 EMG49290.1 - 6.2e-10 39.7 0.9 1.1e-09 38.9 0.2 1.8 2 0 0 2 2 2 1 SET domain Pho88 PF10032.9 EMG49291.1 - 1.7e-82 275.1 0.1 1.9e-82 274.9 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) SNase PF00565.17 EMG49292.1 - 4e-38 130.2 2.9 6e-10 39.6 0.1 5.9 5 1 1 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EMG49292.1 - 1.7e-12 47.4 0.0 3.3e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Amino_oxidase PF01593.24 EMG49293.1 - 3.8e-67 227.5 0.0 4.6e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase UQ_con PF00179.26 EMG49293.1 - 7.7e-44 148.7 0.0 1.2e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NAD_binding_8 PF13450.6 EMG49293.1 - 4.8e-14 52.3 0.0 9.4e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMG49293.1 - 5.4e-05 23.2 0.0 0.00092 19.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 EMG49293.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 MCRA family DAO PF01266.24 EMG49293.1 - 0.0033 17.1 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMG49293.1 - 0.011 15.0 0.0 0.51 9.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMG49293.1 - 0.017 13.8 0.1 0.17 10.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EMG49293.1 - 0.025 15.1 0.1 0.84 10.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMG49293.1 - 0.039 13.2 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family DUF1829 PF08862.10 EMG49293.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF1829 Transp_cyt_pur PF02133.15 EMG49294.1 - 3.1e-21 75.7 27.7 4.6e-21 75.1 27.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin S_4TM PF18159.1 EMG49294.1 - 0.32 10.2 4.0 2.7 7.2 0.1 2.5 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain TENA_THI-4 PF03070.16 EMG49295.1 - 1.6e-10 41.1 0.2 1.9e-10 40.9 0.2 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Proteasome PF00227.26 EMG49296.1 - 9.7e-61 204.6 0.0 1.1e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMG49296.1 - 5.5e-07 29.1 1.0 1.7e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Jag_N PF14804.6 EMG49296.1 - 0.059 13.7 0.2 0.14 12.5 0.2 1.7 1 0 0 1 1 1 0 Jag N-terminus ABC_tran PF00005.27 EMG49297.1 - 1.5e-50 171.2 0.0 3.3e-27 95.7 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMG49297.1 - 4e-15 56.4 0.0 0.025 14.4 0.0 4.9 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMG49297.1 - 9.4e-13 48.1 0.0 0.00019 21.0 0.0 3.6 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMG49297.1 - 3.1e-10 40.9 0.8 0.00019 22.0 0.0 3.4 3 0 0 3 3 2 2 AAA domain Chromo PF00385.24 EMG49297.1 - 1.2e-09 38.0 1.5 3.1e-09 36.6 1.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 EMG49297.1 - 2.4e-08 33.6 0.2 0.0018 18.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMG49297.1 - 8.8e-07 29.0 0.0 0.02 14.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMG49297.1 - 1.1e-06 28.7 0.0 0.035 14.2 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 EMG49297.1 - 8.1e-06 26.2 0.0 0.089 13.0 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 EMG49297.1 - 9.8e-06 25.9 0.0 0.28 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EMG49297.1 - 2.6e-05 24.8 0.0 0.22 12.1 0.0 3.3 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EMG49297.1 - 3.5e-05 24.0 2.8 0.0093 16.1 0.0 4.2 4 0 0 4 4 4 1 Helicase HerA, central domain MeaB PF03308.16 EMG49297.1 - 0.00013 21.0 0.2 0.27 10.2 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EMG49297.1 - 0.00025 21.5 0.1 0.061 13.7 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EMG49297.1 - 0.0004 20.7 0.1 0.56 10.6 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 EMG49297.1 - 0.0004 20.2 5.5 0.15 11.8 0.0 3.5 3 0 0 3 3 2 2 AAA ATPase domain AAA_27 PF13514.6 EMG49297.1 - 0.0011 18.6 0.0 0.8 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMG49297.1 - 0.0012 18.6 0.1 0.9 9.2 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_13 PF13166.6 EMG49297.1 - 0.0038 16.0 0.0 1.2 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMG49297.1 - 0.0064 16.7 0.0 4.3 7.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EMG49297.1 - 0.0067 16.4 0.1 0.37 10.7 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 EMG49297.1 - 0.0071 16.3 0.0 4.8 7.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EMG49297.1 - 0.0091 16.4 0.0 5.9 7.3 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EMG49297.1 - 0.014 14.6 0.7 1 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EMG49297.1 - 0.014 14.7 0.8 4.6 6.5 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_24 PF13479.6 EMG49297.1 - 0.024 14.4 0.2 1.5 8.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 EMG49297.1 - 0.027 14.1 0.4 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.15 EMG49297.1 - 0.036 14.0 0.1 3.3 7.6 0.0 2.9 3 0 0 3 3 2 0 NTPase MukB PF04310.12 EMG49297.1 - 0.037 13.8 0.0 14 5.4 0.0 2.7 2 0 0 2 2 2 0 MukB N-terminal AAA_14 PF13173.6 EMG49297.1 - 0.041 13.9 0.0 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EMG49297.1 - 0.045 13.7 0.2 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SWIRM-assoc_3 PF16498.5 EMG49297.1 - 0.054 13.8 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal Roc PF08477.13 EMG49297.1 - 0.056 13.7 0.0 7.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EMG49297.1 - 0.066 12.4 0.0 4.1 6.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Ploopntkinase3 PF18751.1 EMG49297.1 - 0.13 12.1 0.0 22 4.9 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 cobW PF02492.19 EMG49297.1 - 0.14 11.8 0.9 23 4.5 0.0 3.5 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 EMG49297.1 - 0.18 11.9 1.1 14 5.7 0.0 3.6 3 1 0 3 3 3 0 Dynamin family LRR_8 PF13855.6 EMG49298.1 - 5.2e-12 45.4 16.0 5.1e-07 29.4 1.3 4.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EMG49298.1 - 6.5e-11 42.3 24.5 3.4e-06 27.3 3.0 4.7 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EMG49298.1 - 4.3e-05 23.1 11.8 5.7e-05 22.7 8.7 2.3 1 1 1 2 2 2 1 Leucine-rich repeat Glyco_hydro_3_C PF01915.22 EMG49299.1 - 3.5e-45 154.5 0.0 5e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMG49299.1 - 1.8e-38 132.7 0.0 4.3e-38 131.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMG49299.1 - 4.2e-22 78.0 0.0 7.8e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.16 EMG49300.1 - 5.3e-50 170.3 31.9 6.7e-49 166.7 32.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMG49300.1 - 3.4e-14 52.2 21.6 7.5e-14 51.1 21.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMG49300.1 - 2e-11 43.4 11.1 2e-11 43.4 11.1 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter SafA PF17073.5 EMG49300.1 - 0.089 12.8 0.2 0.39 10.7 0.2 2.1 1 0 0 1 1 1 0 Two-component-system connector protein DUF2530 PF10745.9 EMG49300.1 - 5.5 7.3 7.0 8.3 6.7 1.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) LIP PF03583.14 EMG49302.1 - 3e-78 263.1 0.0 3.8e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EMG49302.1 - 0.039 13.4 0.1 7.4 6.0 0.2 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF5053 PF16476.5 EMG49302.1 - 0.079 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) Peptidase_M16 PF00675.20 EMG49303.1 - 2.1e-29 102.4 0.0 1.1e-28 100.1 0.0 2.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMG49303.1 - 1.5e-09 38.1 3.4 3.5e-05 23.9 0.4 2.9 2 0 0 2 2 2 2 Peptidase M16 inactive domain BES1_N PF05687.13 EMG49304.1 - 3.4 8.0 5.6 4.1 7.8 5.6 1.1 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal SRP1_TIP1 PF00660.17 EMG49305.1 - 6e-21 74.4 0.1 7.2e-21 74.1 0.1 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family FAD_binding_6 PF00970.24 EMG49306.1 - 9.9e-26 90.0 0.0 1.6e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EMG49306.1 - 1.2e-19 70.9 0.0 2.3e-18 66.8 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EMG49306.1 - 1.1e-09 38.6 0.2 3.7e-07 30.4 0.1 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FPL PF09758.9 EMG49306.1 - 0.058 13.4 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein Aldo_ket_red PF00248.21 EMG49307.1 - 2.1e-45 155.2 0.0 2.4e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HMG_CoA_synt_C PF08540.10 EMG49309.1 - 1.5e-117 392.2 5.4 1.9e-117 391.9 5.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EMG49309.1 - 3.6e-93 310.3 0.7 5.4e-93 309.7 0.7 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal PTR PF12789.7 EMG49310.1 - 0.16 12.0 2.9 0.31 11.1 2.9 1.4 1 0 0 1 1 1 0 Phage tail repeat like Ish1 PF10281.9 EMG49311.1 - 1.1e-40 137.6 24.1 1.9e-10 40.9 0.5 7.8 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EMG49311.1 - 1.1e-08 34.6 0.0 3 7.7 0.0 7.2 8 1 0 8 8 8 2 SAP domain HeH PF12949.7 EMG49311.1 - 0.00048 19.8 3.5 0.51 10.1 0.0 4.4 4 0 0 4 4 4 1 HeH/LEM domain Apolipoprotein PF01442.18 EMG49311.1 - 0.00098 19.0 8.1 0.019 14.8 3.3 3.3 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EMG49311.1 - 0.0027 18.2 20.0 26 5.4 1.9 7.1 4 2 2 6 6 6 0 YtxH-like protein Endonuc-dimeris PF09124.10 EMG49311.1 - 0.028 14.6 5.8 1.3 9.3 0.1 4.5 4 0 0 4 4 4 0 T4 recombination endonuclease VII, dimerisation DUF569 PF04601.13 EMG49311.1 - 0.06 13.0 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF569) DUF2344 PF10105.9 EMG49311.1 - 0.077 12.8 0.5 0.33 10.8 0.5 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Glyco_tranf_2_4 PF13704.6 EMG49311.1 - 0.12 13.0 0.3 5.6 7.6 0.1 3.1 2 1 1 3 3 3 0 Glycosyl transferase family 2 HiaBD2 PF15403.6 EMG49311.1 - 0.12 12.8 1.4 10 6.6 0.0 3.5 3 0 0 3 3 3 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Prominin PF05478.11 EMG49311.1 - 0.25 9.2 9.7 0.44 8.4 2.5 3.2 2 1 2 4 4 4 0 Prominin E3_UbLigase_RBR PF18091.1 EMG49311.1 - 0.33 11.1 4.0 34 4.7 0.1 3.7 3 0 0 3 3 3 0 E3 Ubiquitin Ligase RBR C-terminal domain DUF4518 PF15008.6 EMG49311.1 - 0.94 8.6 9.3 0.57 9.3 0.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4518) DUF883 PF05957.13 EMG49311.1 - 8.7 7.0 13.7 17 6.1 3.6 4.7 3 1 2 5 5 4 0 Bacterial protein of unknown function (DUF883) Tubulin PF00091.25 EMG49312.1 - 3.3e-63 213.5 0.0 5.2e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EMG49312.1 - 2.9e-50 169.6 0.0 4.8e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain PIR PF00399.19 EMG49314.1 - 1.8e-25 87.9 127.0 0.0019 17.7 5.6 10.4 10 0 0 10 10 10 9 Yeast PIR protein repeat MF_alpha_N PF05436.11 EMG49314.1 - 0.28 11.1 5.2 0.46 10.4 0.1 3.8 2 2 2 4 4 4 0 Mating factor alpha precursor N-terminus TFIIA PF03153.13 EMG49314.1 - 0.54 10.2 33.7 0.83 9.6 33.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 EMG49315.1 - 1.7e-74 250.5 0.2 2.6e-74 249.9 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49315.1 - 2.2e-33 115.6 0.1 4.4e-23 81.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EMG49315.1 - 1.1e-07 31.4 0.5 0.023 14.0 0.0 3.1 2 1 1 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 EMG49315.1 - 0.001 17.9 0.0 0.0025 16.6 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EMG49315.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMG49315.1 - 0.016 14.2 0.1 0.052 12.5 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EMG49315.1 - 0.022 14.7 0.0 7.9 6.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family 2-Hacid_dh_C PF02826.19 EMG49316.1 - 5.1e-50 169.3 0.0 7.7e-50 168.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMG49316.1 - 1.1e-14 54.2 0.0 1.4e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 EMG49316.1 - 1.3e-05 25.7 0.1 2.8e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EMG49316.1 - 2.4e-05 24.6 0.0 4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EMG49316.1 - 8.4e-05 22.2 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 EMG49316.1 - 0.041 13.9 0.1 4.4 7.3 0.1 2.3 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.21 EMG49316.1 - 0.055 13.5 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 EMG49316.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase VPS28 PF03997.12 EMG49317.1 - 1.7e-60 203.9 1.4 3.2e-60 203.1 1.4 1.4 1 0 0 1 1 1 1 VPS28 protein Sod_Fe_C PF02777.18 EMG49317.1 - 0.0091 16.2 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain YlbD_coat PF14071.6 EMG49317.1 - 0.11 12.8 3.3 0.11 12.7 0.2 2.3 2 1 1 3 3 3 0 Putative coat protein AKAP95 PF04988.12 EMG49317.1 - 0.14 12.4 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 EMG49318.1 - 8.4e-10 38.6 8.6 0.00025 21.3 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG49318.1 - 3.8e-05 24.1 12.5 0.0016 19.1 1.3 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMG49318.1 - 4.5e-05 23.7 0.1 4.5e-05 23.7 0.1 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 EMG49318.1 - 9.2e-05 22.7 0.5 0.00033 20.9 0.5 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EMG49318.1 - 0.0004 20.6 0.4 0.0014 18.8 0.4 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1712 PF08217.11 EMG49318.1 - 0.0043 15.6 7.6 0.0066 15.0 7.6 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) zf-BED PF02892.15 EMG49318.1 - 0.0094 16.0 0.3 0.0094 16.0 0.3 2.2 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_6 PF13912.6 EMG49318.1 - 0.019 15.0 0.5 0.019 15.0 0.5 2.3 3 0 0 3 3 3 0 C2H2-type zinc finger TAFII55_N PF04658.13 EMG49318.1 - 0.58 9.9 6.7 0.76 9.5 0.0 2.9 3 0 0 3 3 3 0 TAFII55 protein conserved region DUF5504 PF17608.2 EMG49319.1 - 0.0083 16.2 0.1 0.0083 16.2 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5504) ESF1 PF18209.1 EMG49319.1 - 0.25 11.3 6.4 1.6 8.7 6.4 2.0 1 1 0 1 1 1 0 Embryo surrounding factor 1 DUF2433 PF10360.9 EMG49320.1 - 1.2e-13 51.2 0.5 3.9e-13 49.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 EMG49320.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain La_HTH_kDCL PF18177.1 EMG49320.1 - 0.17 12.2 0.2 6.4 7.2 0.0 2.9 3 0 0 3 3 3 0 La HTH in kinetoplastid DICER domain NADH_B2 PF14813.6 EMG49321.1 - 0.0004 20.1 0.1 0.00043 20.0 0.1 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Bac_luciferase PF00296.20 EMG49322.1 - 4.6e-52 177.4 0.0 9.9e-52 176.3 0.0 1.5 1 1 0 1 1 1 1 Luciferase-like monooxygenase Tho1_MOS11_C PF18592.1 EMG49323.1 - 1.1e-23 82.8 3.8 3e-23 81.4 3.8 1.8 1 0 0 1 1 1 1 Tho1/MOS11 C-terminal domain SAP PF02037.27 EMG49323.1 - 7.1e-15 54.4 0.1 1.5e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 EMG49323.1 - 0.00021 20.9 1.0 0.00061 19.5 0.2 2.2 2 0 0 2 2 2 1 HeH/LEM domain DUF1664 PF07889.12 EMG49323.1 - 1.2 9.2 5.7 0.6 10.2 1.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) SMBP PF16785.5 EMG49323.1 - 6.1 7.1 9.5 12 6.1 9.3 1.7 1 1 0 1 1 1 0 Small metal-binding protein Ank_4 PF13637.6 EMG49324.1 - 4.2e-07 30.4 0.1 0.0008 19.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMG49324.1 - 1.6e-06 28.6 0.0 2.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EMG49324.1 - 2.1e-05 24.7 0.0 0.078 13.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EMG49324.1 - 0.00018 21.7 0.0 0.00052 20.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMG49324.1 - 0.017 15.6 0.0 0.64 10.8 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat Y_phosphatase2 PF03162.13 EMG49325.1 - 2.9e-50 170.1 0.1 3.4e-50 169.8 0.1 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EMG49325.1 - 5.6e-08 33.0 0.0 7.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EMG49325.1 - 0.0032 17.3 0.3 0.012 15.4 0.3 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMG49325.1 - 0.091 12.3 0.1 0.14 11.7 0.1 1.4 1 1 0 1 1 1 0 Protein-tyrosine phosphatase GIY-YIG PF01541.24 EMG49325.1 - 0.093 13.0 0.1 0.24 11.7 0.1 1.7 2 0 0 2 2 2 0 GIY-YIG catalytic domain PTPlike_phytase PF14566.6 EMG49325.1 - 0.11 12.6 0.2 0.73 9.9 0.0 2.1 1 1 0 2 2 2 0 Inositol hexakisphosphate LRR_8 PF13855.6 EMG49327.1 - 2.6e-13 49.5 18.8 8.6e-05 22.2 0.0 7.5 6 1 3 9 9 9 4 Leucine rich repeat LRR_4 PF12799.7 EMG49327.1 - 8.2e-06 26.1 29.8 0.79 10.2 5.4 8.2 3 2 5 8 8 8 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMG49327.1 - 0.0049 16.8 3.5 8.6 6.7 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich repeat Pedibin PF08182.11 EMG49327.1 - 0.13 12.1 3.2 11 6.0 0.1 3.5 3 1 0 3 3 3 0 Pedibin/Hym-346 family FNIP PF05725.12 EMG49327.1 - 0.21 11.8 30.3 8.7 6.6 0.1 7.3 6 2 1 7 7 7 0 FNIP Repeat LRR_1 PF00560.33 EMG49327.1 - 1.4 9.8 23.3 16 6.5 1.2 8.0 7 3 0 7 7 7 0 Leucine Rich Repeat Ras PF00071.22 EMG49328.1 - 1.1e-57 194.2 0.0 1.4e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG49328.1 - 2e-21 76.4 0.0 4.1e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG49328.1 - 1e-09 38.1 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMG49328.1 - 2.2e-05 24.1 0.5 0.00013 21.6 0.3 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EMG49328.1 - 0.00027 20.9 1.7 0.38 10.7 0.0 2.6 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMG49328.1 - 0.0009 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EMG49328.1 - 0.031 14.3 0.1 0.063 13.3 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DAD PF02109.16 EMG49329.1 - 6.5e-44 148.7 4.7 7.6e-44 148.5 4.7 1.1 1 0 0 1 1 1 1 DAD family DUF5585 PF17823.1 EMG49329.1 - 0.00057 19.0 0.2 0.00073 18.6 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5585) DUF3432 PF11914.8 EMG49329.1 - 0.013 15.7 0.6 0.019 15.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) DUF2207 PF09972.9 EMG49329.1 - 0.035 12.9 0.4 0.038 12.8 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3989 PF13150.6 EMG49329.1 - 0.17 11.6 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) ING PF12998.7 EMG49331.1 - 6e-25 87.8 0.7 1.6e-24 86.4 0.7 1.8 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EMG49331.1 - 4e-05 23.4 7.6 7.9e-05 22.5 7.6 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EMG49331.1 - 0.036 14.3 0.5 0.097 12.9 0.5 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 EMG49331.1 - 0.042 13.4 1.7 0.083 12.5 1.7 1.5 1 0 0 1 1 1 0 PHD-finger CRM1_C PF08767.11 EMG49331.1 - 0.16 11.1 2.6 0.43 9.7 0.1 2.0 2 0 0 2 2 2 0 CRM1 C terminal Hyphal_reg_CWP PF11765.8 EMG49332.1 - 1.3e-115 385.9 6.7 1.5e-115 385.7 6.7 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal GIDE PF12483.8 EMG49332.1 - 0.14 11.5 0.0 0.61 9.5 0.0 1.8 2 0 0 2 2 2 0 E3 Ubiquitin ligase LRR_8 PF13855.6 EMG49334.1 - 0.05 13.4 14.3 0.11 12.3 0.1 5.6 7 1 0 7 7 7 0 Leucine rich repeat bZIP_1 PF00170.21 EMG49335.1 - 1.2e-11 44.6 3.9 2.2e-11 43.7 3.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EMG49335.1 - 1.8e-10 40.7 6.0 3.5e-10 39.8 6.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EMG49335.1 - 0.0011 19.5 3.2 0.0021 18.5 3.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 EMG49335.1 - 0.014 15.9 1.3 0.026 15.0 1.3 1.4 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 EMG49335.1 - 0.037 14.3 1.5 0.063 13.5 1.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper VGPC1_C PF16799.5 EMG49335.1 - 0.081 12.9 2.0 0.57 10.2 0.4 2.7 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 TUG-UBL1 PF11470.8 EMG49336.1 - 4.1e-19 68.6 1.5 9.5e-19 67.4 1.5 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain Transp_cyt_pur PF02133.15 EMG49337.1 - 3.5e-73 246.9 38.3 4.6e-73 246.5 38.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin UCH PF00443.29 EMG49338.1 - 2.5e-52 177.9 4.2 3.8e-52 177.3 4.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMG49338.1 - 1.1e-22 81.1 5.8 1.1e-22 81.1 5.8 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EMG49338.1 - 5.5e-12 45.8 10.8 5.5e-12 45.8 10.8 2.7 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 EMG49338.1 - 0.00063 19.3 7.6 0.0032 17.0 0.1 3.9 3 1 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Glyco_hydro_76 PF03663.14 EMG49339.1 - 8.7e-27 94.6 22.0 1.2e-26 94.1 22.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.13 EMG49339.1 - 4.5e-05 23.0 4.2 0.00019 21.0 0.1 2.9 3 1 1 4 4 4 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 EMG49339.1 - 0.007 15.5 9.0 0.033 13.3 2.7 2.4 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 EMG49339.1 - 0.0091 15.3 0.3 1.2 8.3 0.0 2.7 1 1 2 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Rap1-DNA-bind PF09197.10 EMG49340.1 - 2.6e-23 82.7 11.7 7e-19 68.4 0.4 3.9 3 1 1 4 4 4 3 Rap1, DNA-binding BRCT_2 PF16589.5 EMG49340.1 - 1.7e-13 50.8 0.0 4.7e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 EMG49340.1 - 2.7e-09 37.1 2.0 9.5e-05 22.5 0.2 2.7 2 0 0 2 2 2 2 Rap1 Myb domain Myb_DNA-binding PF00249.31 EMG49340.1 - 0.0003 20.9 2.1 0.0034 17.6 0.0 2.8 2 1 0 2 2 2 1 Myb-like DNA-binding domain BRCT PF00533.26 EMG49340.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain ABC_membrane PF00664.23 EMG49341.1 - 6e-57 193.4 44.7 8.3e-42 143.7 15.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMG49341.1 - 8.4e-46 155.9 0.7 1.1e-29 103.7 0.0 3.5 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EMG49341.1 - 1.5e-09 37.7 8.5 0.013 15.0 0.1 4.3 2 2 2 4 4 4 4 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMG49341.1 - 8e-07 29.1 1.6 0.0044 16.9 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EMG49341.1 - 1.9e-06 27.5 1.3 0.01 15.6 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EMG49341.1 - 7.2e-06 26.0 10.9 0.051 13.4 0.1 5.2 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EMG49341.1 - 1e-05 25.6 1.2 0.025 14.7 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EMG49341.1 - 0.00043 20.7 0.1 0.047 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EMG49341.1 - 0.00084 19.9 3.9 0.13 12.9 0.1 3.7 5 0 0 5 5 2 1 AAA domain AAA_23 PF13476.6 EMG49341.1 - 0.0013 19.3 9.3 0.14 12.7 0.6 3.2 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 EMG49341.1 - 0.0029 16.9 0.2 0.77 9.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 EMG49341.1 - 0.0036 17.1 1.5 1.4 8.6 0.1 2.6 2 1 0 2 2 2 2 AAA domain Vps51 PF08700.11 EMG49341.1 - 0.0038 17.3 0.3 0.028 14.5 0.1 2.6 2 0 0 2 2 2 1 Vps51/Vps67 Dynamin_N PF00350.23 EMG49341.1 - 0.0042 17.1 1.1 1.2 9.2 0.2 2.7 2 0 0 2 2 2 1 Dynamin family AAA PF00004.29 EMG49341.1 - 0.019 15.4 1.4 1.9 8.9 0.2 3.3 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 EMG49341.1 - 0.022 14.6 0.5 13 5.5 0.2 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EMG49341.1 - 0.025 14.2 2.4 0.068 12.8 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EMG49341.1 - 0.026 13.6 0.1 0.026 13.6 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF815 PF05673.13 EMG49341.1 - 0.043 13.0 0.1 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.9 EMG49341.1 - 0.058 12.2 2.3 4.5 6.0 0.1 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NACHT PF05729.12 EMG49341.1 - 0.073 13.0 0.6 0.7 9.8 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 EMG49341.1 - 0.11 12.0 2.2 11 5.5 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF87 PF01935.17 EMG49341.1 - 0.12 12.5 1.8 0.32 11.1 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 EMG49341.1 - 0.15 12.3 5.4 2.7 8.3 0.1 3.7 3 1 0 3 3 2 0 AAA domain AAA_28 PF13521.6 EMG49341.1 - 0.24 11.6 0.8 1.8 8.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EMG49341.1 - 0.27 11.5 3.2 5.4 7.3 0.1 3.4 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 EMG49341.1 - 0.28 10.1 0.6 17 4.3 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 EMG49341.1 - 0.56 10.2 3.4 1 9.4 0.1 2.6 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Phosducin PF02114.16 EMG49342.1 - 3.1e-13 49.3 1.8 3.1e-13 49.3 1.8 1.7 1 1 1 2 2 2 1 Phosducin DHQS PF01959.16 EMG49342.1 - 0.019 13.9 0.2 0.019 13.9 0.2 1.4 2 0 0 2 2 2 0 3-dehydroquinate synthase II DUF4961 PF16328.5 EMG49342.1 - 0.11 11.7 0.2 0.16 11.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4961) LRR_4 PF12799.7 EMG49343.1 - 2.2e-08 34.3 64.3 0.0093 16.4 3.5 11.7 8 4 2 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG49343.1 - 1.1e-05 25.1 14.8 3.2e-05 23.6 2.7 7.9 7 2 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.6 EMG49343.1 - 0.016 15.2 21.7 1.1 9.5 0.4 9.4 10 0 0 10 10 10 0 Leucine Rich repeat Glyco_hydro_17 PF00332.18 EMG49344.1 - 1.5e-07 31.4 0.6 2.9e-07 30.4 0.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PPR_2 PF13041.6 EMG49345.1 - 3.1e-14 52.9 0.1 2.1e-10 40.6 0.0 3.6 3 1 0 3 3 3 2 PPR repeat family MA3 PF02847.17 EMG49346.1 - 9.9e-19 67.4 1.9 1.2e-18 67.1 0.6 1.8 2 0 0 2 2 2 1 MA3 domain Cytochrom_C PF00034.21 EMG49347.1 - 4.8e-12 46.8 0.0 7.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EMG49347.1 - 7.2e-07 29.4 2.2 6.1e-06 26.5 2.2 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EMG49347.1 - 0.11 12.2 0.9 0.6 9.8 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c-550 domain CCP_MauG PF03150.14 EMG49347.1 - 0.13 12.9 0.0 0.14 12.8 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase PI31_Prot_C PF08577.11 EMG49348.1 - 1.3e-13 51.9 14.9 3.1e-13 50.7 14.9 1.7 1 0 0 1 1 1 1 PI31 proteasome regulator CTP_transf_like PF01467.26 EMG49349.1 - 4.4e-08 33.4 0.1 2.7e-07 30.9 0.1 2.1 1 1 0 1 1 1 1 Cytidylyltransferase-like Cache_3-Cache_2 PF17201.4 EMG49349.1 - 0.19 11.0 0.2 0.29 10.4 0.2 1.2 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain USP7_ICP0_bdg PF12436.8 EMG49350.1 - 8e-48 162.8 2.4 1.5e-37 129.2 0.4 3.6 3 1 1 4 4 4 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 EMG49350.1 - 1.5e-34 119.6 3.8 1.8e-34 119.4 2.4 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 EMG49350.1 - 2.5e-26 92.7 1.6 2.5e-26 92.7 1.6 4.4 6 1 1 7 7 7 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 EMG49350.1 - 2.4e-14 53.7 0.1 4.5e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MPP6 PF10175.9 EMG49350.1 - 2.2 8.8 5.8 6.8 7.2 5.8 1.8 1 0 0 1 1 1 0 M-phase phosphoprotein 6 FAM176 PF14851.6 EMG49350.1 - 2.8 7.6 6.0 8.8 6.0 6.0 1.8 1 0 0 1 1 1 0 FAM176 family Rhodanese PF00581.20 EMG49351.1 - 1.3e-14 54.6 0.0 1.8e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain Glucosamine_iso PF01182.20 EMG49352.1 - 8.8e-54 182.7 0.0 1.5e-53 182.0 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Mucin_bdg PF03272.13 EMG49352.1 - 0.052 13.6 0.4 0.11 12.5 0.4 1.5 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module ABC_membrane PF00664.23 EMG49353.1 - 8.9e-65 219.1 40.0 2.7e-35 122.4 22.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMG49353.1 - 1.4e-48 164.9 0.7 8.7e-29 100.8 0.1 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMG49353.1 - 1.1e-08 34.8 6.8 0.024 14.1 0.1 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMG49353.1 - 4.7e-08 32.7 0.8 0.00061 19.5 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EMG49353.1 - 1.1e-05 25.4 13.4 0.21 11.4 0.1 5.4 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EMG49353.1 - 9e-05 22.5 1.5 0.1 12.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMG49353.1 - 0.0001 22.2 1.3 0.084 12.8 0.4 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EMG49353.1 - 0.0009 19.8 2.6 2.3 8.8 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EMG49353.1 - 0.0011 19.3 0.4 0.32 11.3 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EMG49353.1 - 0.006 16.3 0.5 2.4 7.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.17 EMG49353.1 - 0.012 15.4 0.8 13 5.5 0.1 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 EMG49353.1 - 0.013 14.8 0.0 0.98 8.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EMG49353.1 - 0.024 14.2 1.3 1.5 8.4 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 EMG49353.1 - 0.039 13.7 0.0 21 4.8 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.6 EMG49353.1 - 0.041 14.4 22.3 0.078 13.5 5.0 3.9 2 1 1 3 3 2 0 AAA domain AAA_22 PF13401.6 EMG49353.1 - 0.055 13.7 1.6 23 5.3 0.2 3.4 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 EMG49353.1 - 0.11 11.4 0.1 13 4.7 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EMG49353.1 - 0.14 12.3 0.0 0.14 12.3 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain Arteri_Gl PF00951.18 EMG49353.1 - 0.69 9.7 8.9 0.081 12.7 3.0 2.4 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein zf-C2H2_4 PF13894.6 EMG49355.1 - 0.029 15.2 0.7 0.072 14.0 0.4 1.9 1 1 0 1 1 1 0 C2H2-type zinc finger DUF4407 PF14362.6 EMG49356.1 - 7.5 5.8 9.7 14 4.9 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mis12 PF05859.12 EMG49358.1 - 1.3e-41 141.8 0.9 4.3e-41 140.1 0.2 1.9 2 0 0 2 2 2 1 Mis12 protein GABP-alpha PF11620.8 EMG49358.1 - 3.1 8.1 6.7 7.4 6.8 0.0 3.7 3 2 1 4 4 4 0 GA-binding protein alpha chain 2OG-FeII_Oxy PF03171.20 EMG49359.1 - 1e-11 45.2 0.0 2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EMG49359.1 - 3.8e-09 37.3 0.0 7.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Dus PF01207.17 EMG49360.1 - 9.1e-48 162.9 0.0 2.1e-47 161.8 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.18 EMG49360.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Tex_YqgF PF16921.5 EMG49360.1 - 0.14 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Tex protein YqgF-like domain Tim17 PF02466.19 EMG49361.1 - 7.6e-28 97.1 0.5 1e-27 96.7 0.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ost4 PF10215.9 EMG49362.1 - 2.3e-15 56.1 1.8 3e-15 55.7 1.8 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Neugrin PF06413.11 EMG49363.1 - 0.00019 21.5 0.9 0.0005 20.1 0.1 1.8 2 0 0 2 2 2 1 Neugrin DUF4065 PF13274.6 EMG49363.1 - 0.028 15.3 0.2 0.039 14.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) Endonuc-PvuII PF09225.10 EMG49363.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease PvuII HTH_32 PF13565.6 EMG49363.1 - 0.42 11.3 0.1 0.42 11.3 0.1 2.4 2 1 0 2 2 2 0 Homeodomain-like domain Peptidase_M20 PF01546.28 EMG49365.1 - 2.7e-33 115.4 0.0 3.4e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMG49365.1 - 4.6e-08 32.9 0.2 1.1e-07 31.7 0.2 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMG49365.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 RRM_1 PF00076.22 EMG49366.1 - 9.6e-18 63.8 0.0 1.3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMG49366.1 - 0.036 13.6 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMG49366.1 - 0.051 13.4 0.0 0.074 12.9 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif PMI_typeI PF01238.21 EMG49367.1 - 1.2e-155 518.4 0.0 1.4e-155 518.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 EMG49367.1 - 0.00055 19.8 0.0 0.23 11.4 0.0 2.7 3 0 0 3 3 3 2 AraC-like ligand binding domain Thioredoxin PF00085.20 EMG49368.1 - 2.4e-17 62.8 0.4 1.5e-15 57.0 0.1 3.3 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 EMG49368.1 - 9.8e-05 22.3 6.8 0.00012 22.0 0.4 3.8 3 1 2 5 5 5 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMG49368.1 - 0.0052 17.1 0.1 0.0052 17.1 0.1 3.3 3 1 1 4 4 4 1 Thioredoxin-like ERp29_N PF07912.13 EMG49368.1 - 0.064 13.4 0.0 0.31 11.2 0.0 2.1 1 0 0 1 1 1 0 ERp29, N-terminal domain Thioredoxin_2 PF13098.6 EMG49368.1 - 0.15 12.5 2.4 1.4 9.4 0.1 3.1 3 0 0 3 3 3 0 Thioredoxin-like domain Mito_carr PF00153.27 EMG49369.1 - 2.5e-76 251.7 6.0 7.7e-27 93.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18p PF00861.22 EMG49369.1 - 0.42 11.0 1.2 1.3 9.4 0.1 2.3 3 0 0 3 3 3 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Serine_protease PF18405.1 EMG49369.1 - 0.48 9.5 4.9 14 4.7 0.0 3.4 2 1 1 3 3 3 0 Gammaproteobacterial serine protease NAD_binding_6 PF08030.12 EMG49370.1 - 9.8e-26 90.7 0.0 1.4e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMG49370.1 - 1.2e-24 86.5 0.0 2.8e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EMG49370.1 - 8.7e-22 77.6 13.7 8.7e-22 77.6 13.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EMG49370.1 - 0.059 14.0 0.0 15 6.3 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain FNIP PF05725.12 EMG49371.1 - 0.049 13.8 23.4 6.4 7.0 0.4 7.9 9 0 0 9 9 9 0 FNIP Repeat LRR_4 PF12799.7 EMG49371.1 - 0.86 10.1 32.8 1.1 9.8 1.6 9.1 5 4 4 9 9 9 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG49371.1 - 1.8 8.4 21.0 1 9.2 0.0 6.6 7 1 0 7 7 7 0 Leucine rich repeat Bac_luciferase PF00296.20 EMG49372.1 - 1.7e-53 182.1 0.0 2.6e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase PQ-loop PF04193.14 EMG49373.1 - 9.8e-35 118.1 7.2 2.9e-19 68.6 0.8 3.5 5 0 0 5 5 5 2 PQ loop repeat TRAM_LAG1_CLN8 PF03798.16 EMG49373.1 - 0.004 16.9 4.1 1.8 8.3 0.0 2.3 1 1 0 2 2 2 2 TLC domain DUF4306 PF14154.6 EMG49373.1 - 0.062 13.5 0.8 0.062 13.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) Epiglycanin_C PF14654.6 EMG49373.1 - 0.076 13.1 1.7 0.15 12.1 0.5 1.9 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region YrhC PF14143.6 EMG49373.1 - 0.13 12.4 1.1 0.36 10.9 0.2 2.3 2 0 0 2 2 2 0 YrhC-like protein SWIRM PF04433.17 EMG49374.1 - 1.1e-08 35.3 0.1 3.1e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain YicC_N PF03755.13 EMG49374.1 - 0.083 13.3 0.7 0.18 12.2 0.5 1.7 2 0 0 2 2 2 0 YicC-like family, N-terminal region ParA PF10609.9 EMG49375.1 - 5.9e-67 225.7 0.8 7.7e-67 225.3 0.8 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EMG49375.1 - 5.2e-10 39.5 0.0 6.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EMG49375.1 - 2.4e-08 33.6 0.1 6e-07 29.0 0.0 2.1 1 1 1 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 EMG49375.1 - 5e-08 33.0 0.0 9.2e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EMG49375.1 - 8.9e-05 21.8 0.3 0.00016 21.0 0.1 1.4 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 EMG49375.1 - 0.0012 17.9 0.1 0.0017 17.4 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 EMG49375.1 - 0.0033 17.0 0.0 0.004 16.7 0.0 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 EMG49375.1 - 0.0041 17.0 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_25 PF13481.6 EMG49375.1 - 0.023 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EMG49375.1 - 0.061 12.5 0.1 0.096 11.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 EMG49375.1 - 0.08 12.8 0.3 0.17 11.8 0.3 1.6 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 EMG49375.1 - 0.1 12.2 0.1 2.2 7.9 0.2 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CLP1_P PF16575.5 EMG49375.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 EMG49375.1 - 0.13 12.7 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 EMG49375.1 - 0.17 11.8 0.0 1.9 8.4 0.1 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain Nop16 PF09420.10 EMG49376.1 - 7.5e-64 215.6 16.0 8.6e-64 215.4 16.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Nsp1_C PF05064.13 EMG49377.1 - 0.0005 19.9 0.7 0.00057 19.7 0.7 1.1 1 0 0 1 1 1 1 Nsp1-like C-terminal region CLZ PF16526.5 EMG49377.1 - 0.0038 17.6 0.7 0.0045 17.3 0.7 1.1 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 EMG49377.1 - 0.0057 16.0 1.4 0.0058 16.0 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Helo_like_N PF17111.5 EMG49377.1 - 0.011 15.1 2.1 0.011 15.1 2.1 1.0 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Vps54_N PF10475.9 EMG49377.1 - 0.019 14.3 0.1 0.021 14.1 0.1 1.0 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Halogen_Hydrol PF10112.9 EMG49377.1 - 0.031 14.3 1.5 0.033 14.2 1.5 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein SGT1 PF07093.11 EMG49377.1 - 0.064 11.7 2.9 0.062 11.7 2.9 1.0 1 0 0 1 1 1 0 SGT1 protein Calici_MSP PF05752.11 EMG49377.1 - 0.072 12.9 0.3 0.08 12.8 0.3 1.1 1 0 0 1 1 1 0 Calicivirus minor structural protein GrpE PF01025.19 EMG49377.1 - 0.26 10.9 4.2 0.28 10.8 4.2 1.0 1 0 0 1 1 1 0 GrpE HMGL-like PF00682.19 EMG49378.1 - 2e-82 276.7 0.0 3.1e-82 276.1 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EMG49378.1 - 2.9e-27 95.2 0.0 5.3e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Syntaxin PF00804.25 EMG49379.1 - 6.4e-22 78.2 20.0 6.4e-22 78.2 20.0 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 EMG49379.1 - 4.9e-12 45.7 1.3 4.9e-12 45.7 1.3 2.2 2 0 0 2 2 2 1 SNARE domain Pox_EPC_I2-L1 PF12575.8 EMG49379.1 - 0.079 13.2 1.7 2.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Synaptobrevin PF00957.21 EMG49379.1 - 0.11 12.4 0.3 0.11 12.4 0.3 3.2 3 1 0 3 3 3 0 Synaptobrevin COG2 PF06148.11 EMG49379.1 - 0.19 11.8 17.3 0.75 9.9 0.4 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 EMG49379.1 - 0.31 11.3 11.1 0.29 11.4 1.2 3.9 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Neur_chan_memb PF02932.16 EMG49379.1 - 0.42 10.6 8.6 0.035 14.1 2.7 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FUSC PF04632.12 EMG49379.1 - 0.62 8.5 1.2 0.92 8.0 1.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Herpes_US9 PF06072.11 EMG49379.1 - 0.96 9.4 3.5 0.39 10.6 0.5 1.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 PBP1_TM PF14812.6 EMG49379.1 - 0.98 9.8 0.0 0.98 9.8 0.0 3.1 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mobilization_B PF17511.2 EMG49379.1 - 1.6 9.1 5.1 2 8.8 0.3 2.5 2 1 0 2 2 2 0 Mobilization protein B MCPsignal PF00015.21 EMG49379.1 - 4.3 7.1 15.2 0.61 9.9 1.5 3.1 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF745 PF05335.13 EMG49379.1 - 9.2 5.9 19.7 0.44 10.2 9.9 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF745) IPK PF03770.16 EMG49380.1 - 3.1e-55 187.1 0.0 4e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase GTP_EFTU PF00009.27 EMG49381.1 - 9.7e-44 149.2 0.0 8e-43 146.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EMG49381.1 - 1.6e-36 125.0 0.3 4.5e-36 123.6 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EMG49381.1 - 4.3e-08 33.4 0.3 1.4e-07 31.8 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMG49381.1 - 0.00097 19.2 0.2 0.0063 16.6 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3340 PF11818.8 EMG49381.1 - 0.63 10.2 8.7 1.5 8.9 8.0 2.1 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) VHS PF00790.19 EMG49382.1 - 3.9e-16 59.2 0.0 8.1e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EMG49382.1 - 0.0024 18.1 0.0 0.0088 16.3 0.0 2.0 1 1 0 1 1 1 1 GAT domain UPF0240 PF06784.11 EMG49382.1 - 0.59 10.2 6.8 0.23 11.5 2.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) YL1 PF05764.13 EMG49382.1 - 3.2 7.8 18.6 2.4 8.2 7.1 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Mito_fiss_reg PF05308.11 EMG49382.1 - 3.3 7.7 13.0 2.9 7.9 1.3 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Nop14 PF04147.12 EMG49382.1 - 3.5 5.7 16.5 0.3 9.2 4.9 2.2 2 0 0 2 2 2 0 Nop14-like family Use1 PF09753.9 EMG49384.1 - 0.0058 16.4 0.0 0.0071 16.1 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Rad17 PF03215.15 EMG49384.1 - 0.019 14.9 0.1 0.023 14.6 0.1 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain Syja_N PF02383.18 EMG49385.1 - 4.9e-31 108.2 0.1 6.6e-31 107.8 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain Hyphal_reg_CWP PF11765.8 EMG49386.1 - 5.3e-133 443.0 12.5 6e-133 442.8 12.5 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 EMG49386.1 - 0.00031 20.2 7.3 0.00031 20.2 7.3 2.3 3 0 0 3 3 3 1 Hyphally regulated cell wall GPI-anchored protein 1 SRI PF08236.11 EMG49388.1 - 1.5e-22 79.5 3.6 1.5e-22 79.5 3.6 3.6 2 1 1 3 3 3 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EMG49388.1 - 9.2e-15 55.4 0.4 9.2e-15 55.4 0.4 4.4 3 2 0 3 3 3 1 SET domain AWS PF17907.1 EMG49388.1 - 1.6e-13 50.4 10.6 1.6e-13 50.4 10.6 1.8 2 0 0 2 2 2 1 AWS domain WW PF00397.26 EMG49388.1 - 2.1e-11 43.7 4.8 4.5e-11 42.6 4.8 1.6 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 EMG49388.1 - 0.0084 16.1 1.6 0.0084 16.1 1.6 2.9 3 0 0 3 3 3 1 TFIIS helical bundle-like domain HTH_15 PF12324.8 EMG49388.1 - 0.036 14.0 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Mso1_C PF14477.6 EMG49388.1 - 0.081 13.3 4.8 0.24 11.8 4.8 1.8 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 NAD_Gly3P_dh_N PF01210.23 EMG49389.1 - 3.3e-50 170.1 0.0 4.9e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EMG49389.1 - 2.4e-42 144.6 0.2 4.1e-42 143.8 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EMG49389.1 - 0.0017 18.9 0.0 3.5 8.3 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EMG49389.1 - 0.095 12.6 0.4 13 5.6 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EMG49389.1 - 0.14 12.6 0.0 0.55 10.7 0.0 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain zf-C2H2 PF00096.26 EMG49390.1 - 7.1e-10 38.8 5.4 4.2e-05 23.8 1.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG49390.1 - 1.4e-08 34.9 3.8 0.003 18.3 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMG49390.1 - 0.028 14.7 4.7 1.2 9.5 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Prothymosin PF03247.14 EMG49390.1 - 1.2 9.7 18.9 0.35 11.4 5.4 3.4 3 0 0 3 3 3 0 Prothymosin/parathymosin family zf-C2H2_3rep PF18868.1 EMG49390.1 - 5.7 7.6 9.4 0.33 11.6 0.7 2.7 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats CAF1C_H4-bd PF12265.8 EMG49391.1 - 0.065 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex TruD PF01142.18 EMG49392.1 - 4.6e-69 233.2 1.8 8.3e-68 229.1 0.4 2.8 2 2 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) R3H-assoc PF13902.6 EMG49392.1 - 0.077 13.4 10.2 0.34 11.3 0.1 2.8 2 1 0 2 2 2 0 R3H-associated N-terminal domain Pkinase PF00069.25 EMG49393.1 - 3.6e-71 239.6 0.0 5e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49393.1 - 2.6e-38 131.8 0.0 3.6e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG49393.1 - 8.7e-09 35.1 0.0 7e-07 28.8 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EMG49393.1 - 2.2e-06 26.7 0.1 6.5e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EMG49393.1 - 0.01 15.3 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF4120 PF13496.6 EMG49393.1 - 0.046 14.1 0.0 0.22 11.9 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) APH PF01636.23 EMG49393.1 - 0.071 13.0 0.4 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EMG49393.1 - 0.098 12.0 0.1 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family AMP-binding PF00501.28 EMG49394.1 - 4.2e-86 289.2 0.0 5.1e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMG49394.1 - 1.3e-25 90.2 0.3 7.7e-24 84.5 0.2 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EMG49394.1 - 2.4e-17 62.6 0.5 5.2e-17 61.5 0.5 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus HEM4 PF02602.15 EMG49395.1 - 5.3e-39 133.9 0.0 6.8e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TIG PF01833.24 EMG49396.1 - 1.6e-11 44.1 2.7 3.2e-11 43.1 0.2 2.9 4 0 0 4 4 4 1 IPT/TIG domain RRM_1 PF00076.22 EMG49397.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 EMG49399.1 - 1.4e-92 310.2 1.5 1.4e-92 310.2 1.5 2.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EMG49399.1 - 5.2e-22 78.4 0.1 1.8e-21 76.6 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding Pox_A_type_inc PF04508.12 EMG49399.1 - 0.019 14.8 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Med9 PF07544.13 EMG49399.1 - 0.17 12.0 8.9 0.11 12.6 0.4 3.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 COMP PF11598.8 EMG49399.1 - 0.18 12.3 7.9 0.39 11.2 0.7 3.2 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein Fib_alpha PF08702.10 EMG49399.1 - 1.5 9.0 12.6 8.7 6.5 0.4 3.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 EMG49399.1 - 2.5 7.5 17.8 0.016 14.7 4.3 2.8 2 1 1 3 3 3 0 Golgin subfamily A member 5 DUF641 PF04859.12 EMG49399.1 - 5.8 7.3 10.9 31 4.9 0.2 3.5 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) APG6_N PF17675.1 EMG49399.1 - 7.7 7.1 8.2 0.73 10.4 1.1 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region Metallophos PF00149.28 EMG49400.1 - 4.4e-10 40.4 9.4 4.4e-10 40.4 9.4 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_8 PF13181.6 EMG49401.1 - 3.7e-07 29.8 5.2 0.17 12.2 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMG49401.1 - 9.6e-05 22.0 0.6 0.14 12.0 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMG49401.1 - 0.00017 22.1 0.1 9.4 7.4 0.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMG49401.1 - 0.0014 19.1 0.2 0.84 10.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG49401.1 - 0.0028 17.9 4.5 0.0086 16.3 0.9 3.3 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EMG49401.1 - 0.011 16.1 6.5 0.016 15.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMG49401.1 - 0.025 14.8 0.1 19 5.6 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMG49401.1 - 0.041 14.0 6.6 1.7 9.0 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 EMG49402.1 - 3.2e-39 134.9 0.0 5.6e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49402.1 - 1.7e-27 96.3 0.0 2.8e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EMG49402.1 - 8.4e-06 25.3 0.1 3.3e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMG49402.1 - 5.1e-05 22.4 0.1 5.1e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EMG49402.1 - 0.0025 17.2 0.1 0.015 14.6 0.1 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMG49402.1 - 0.019 13.7 1.3 0.027 13.2 0.1 1.8 2 0 0 2 2 2 0 Fungal protein kinase ORC2 PF04084.14 EMG49403.1 - 4.8e-100 334.7 0.0 6.9e-100 334.2 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 GyrI-like PF06445.15 EMG49403.1 - 0.081 13.2 0.1 0.75 10.1 0.2 2.3 2 0 0 2 2 2 0 GyrI-like small molecule binding domain DUF4637 PF15470.6 EMG49403.1 - 4.6 7.0 9.0 8.1 6.1 8.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DRMBL PF07522.14 EMG49404.1 - 0.00024 21.2 0.1 0.00076 19.6 0.1 1.9 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EMG49404.1 - 0.00036 20.1 0.0 0.00068 19.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 EMG49404.1 - 0.0044 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EMG49404.1 - 0.13 12.3 0.0 0.35 10.8 0.0 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily RRM_1 PF00076.22 EMG49405.1 - 5.6e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EMG49405.1 - 0.0016 18.4 0.4 0.04 14.0 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif DUF2854 PF11016.8 EMG49405.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) CCSAP PF15748.5 EMG49405.1 - 0.1 12.7 2.7 0.19 11.9 0.0 2.4 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated ATPase PF06745.13 EMG49405.1 - 0.12 11.7 0.2 3.7 6.8 0.0 2.1 2 0 0 2 2 2 0 KaiC DUF2428 PF10350.9 EMG49406.1 - 1.4e-28 99.9 0.0 3.1e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EMG49406.1 - 0.007 16.5 1.3 56 4.4 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat V-ATPase_H_N PF03224.14 EMG49406.1 - 5.2 6.3 13.7 3 7.0 1.2 3.2 3 1 0 3 3 3 0 V-ATPase subunit H SNF2_N PF00176.23 EMG49407.1 - 5.8e-58 196.3 0.6 9.7e-58 195.5 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMG49407.1 - 8e-18 64.8 0.1 9.8e-17 61.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG49407.1 - 8.4e-16 58.4 0.4 3.6e-15 56.4 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMG49407.1 - 2.5e-09 37.1 0.4 1.2e-08 34.9 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EMG49407.1 - 5.1e-05 22.6 7.5 0.00014 21.1 5.6 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.9 EMG49407.1 - 0.0053 16.0 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 EMG49407.1 - 0.0087 15.3 0.1 0.016 14.4 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase bVLRF1 PF18826.1 EMG49408.1 - 1.3e-61 206.8 0.2 2.8e-61 205.8 0.2 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EMG49408.1 - 4.5e-06 26.8 0.3 9.3e-06 25.8 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMG49408.1 - 7.7e-05 23.2 0.0 0.00021 21.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMG49408.1 - 0.028 15.0 0.3 0.092 13.4 0.1 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMG49408.1 - 0.07 13.7 0.2 0.73 10.6 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 EMG49408.1 - 0.13 12.8 0.6 0.31 11.6 0.6 1.7 1 0 0 1 1 1 0 Ankyrin repeat 40S_SA_C PF16122.5 EMG49408.1 - 0.72 11.3 6.4 3.5 9.0 3.0 2.8 2 0 0 2 2 2 0 40S ribosomal protein SA C-terminus Usp PF00582.26 EMG49408.1 - 4.7 7.7 5.6 1.5 9.3 0.5 2.7 3 0 0 3 3 3 0 Universal stress protein family DUF2868 PF11067.8 EMG49408.1 - 9.4 5.6 6.9 30 4.0 6.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) URO-D PF01208.17 EMG49409.1 - 4.8e-127 423.9 0.0 5.4e-127 423.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Peptidase_M28 PF04389.17 EMG49410.1 - 4.2e-42 144.1 0.1 8.4e-42 143.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 EMG49410.1 - 0.00017 21.3 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EMG49410.1 - 0.0027 16.8 0.0 0.0069 15.4 0.0 1.5 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase TraT PF05818.12 EMG49411.1 - 0.11 12.1 3.4 0.12 12.0 3.4 1.0 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Ldh_1_N PF00056.23 EMG49412.1 - 1.2e-44 151.9 1.0 1.8e-44 151.3 1.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EMG49412.1 - 4.5e-38 130.8 0.0 8.4e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 EMG49412.1 - 0.00041 19.4 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ATG27 PF09451.10 EMG49413.1 - 2.5e-59 201.3 1.0 3.2e-59 200.9 1.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EMG49413.1 - 0.00057 20.0 0.4 0.58 10.2 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF2165 PF09933.9 EMG49413.1 - 0.021 14.8 0.1 0.038 14.0 0.1 1.4 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) DMRL_synthase PF00885.19 EMG49413.1 - 0.042 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase MTHFR PF02219.17 EMG49414.1 - 3.9e-107 357.8 0.0 5.7e-107 357.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF5023 PF16426.5 EMG49414.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5023) zf-CCCH_7 PF18586.1 EMG49414.1 - 0.086 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 ERCC4 PF02732.15 EMG49415.1 - 7.8e-21 74.9 9.9 2.3e-20 73.4 0.0 4.9 4 1 0 4 4 4 1 ERCC4 domain Helitron_like_N PF14214.6 EMG49415.1 - 0.052 13.8 4.0 0.75 10.0 0.2 2.8 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus RAP1 PF07218.11 EMG49416.1 - 1.9 6.7 12.7 2.3 6.4 12.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Porphobil_deam PF01379.20 EMG49417.1 - 6.4e-73 244.6 0.0 8.9e-73 244.1 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EMG49417.1 - 2.2e-21 76.0 0.1 3.9e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GATA PF00320.27 EMG49418.1 - 1.4e-07 31.0 6.1 1.4e-07 31.0 6.1 1.9 2 0 0 2 2 2 1 GATA zinc finger RBM39linker PF15519.6 EMG49418.1 - 0.12 13.5 6.8 16 6.7 0.0 3.0 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein ADD_DNMT3 PF17980.1 EMG49418.1 - 0.5 10.4 6.9 0.33 11.0 3.0 2.4 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Suf PF05843.14 EMG49418.1 - 4.2 7.3 16.3 0.21 11.5 10.6 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 EMG49418.1 - 5.7 5.1 16.0 7.8 4.6 16.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ubiquitin PF00240.23 EMG49419.1 - 2.8e-23 81.5 0.2 4.1e-23 80.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EMG49419.1 - 1.4e-11 44.0 0.1 2.3e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 EMG49419.1 - 2e-08 34.0 3.5 5.2e-08 32.6 0.1 2.7 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 EMG49419.1 - 2.7e-06 27.4 0.1 5.3e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMG49419.1 - 3.3e-06 27.5 0.2 7.6e-06 26.3 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 EMG49419.1 - 6.3e-05 23.5 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EMG49419.1 - 0.012 15.7 0.2 5.7 7.1 0.0 2.4 1 1 1 2 2 2 0 Ubiquitin-like domain DUF4625 PF15418.6 EMG49419.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) TBK1_ULD PF18396.1 EMG49419.1 - 0.039 13.9 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain GerD PF17898.1 EMG49419.1 - 0.054 13.4 9.5 0.14 12.1 9.5 1.7 1 1 0 1 1 1 0 Spore germination GerD central core domain HOIP-UBA PF16678.5 EMG49419.1 - 0.082 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair YukD PF08817.10 EMG49419.1 - 0.13 12.9 0.0 0.44 11.3 0.0 1.9 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD XPC-binding PF09280.11 EMG49419.1 - 1.4 8.7 19.2 2.8 7.7 14.6 2.5 1 1 1 2 2 2 0 XPC-binding domain STI1 PF17830.1 EMG49419.1 - 4.4 7.3 24.3 32 4.6 7.5 2.8 1 1 1 2 2 2 0 STI1 domain TAF8_C PF10406.9 EMG49420.1 - 6e-19 68.3 1.9 6e-19 68.3 1.9 3.3 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term CENP-S PF15630.6 EMG49420.1 - 6.4e-05 23.3 0.0 0.00026 21.3 0.0 2.1 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 EMG49420.1 - 0.00026 20.9 0.0 0.00072 19.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Glyco_transf_20 PF00982.21 EMG49421.1 - 3.2e-151 504.2 0.4 4.5e-151 503.7 0.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EMG49421.1 - 1.7e-15 56.8 0.0 3e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase PAS_3 PF08447.12 EMG49421.1 - 0.17 12.2 0.1 0.89 9.9 0.0 2.2 2 0 0 2 2 2 0 PAS fold CTK3 PF12243.8 EMG49422.1 - 2.2e-26 92.2 5.1 3.9e-26 91.5 3.4 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EMG49422.1 - 3.1e-22 78.5 5.1 6.4e-22 77.5 5.1 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus EF-hand_4 PF12763.7 EMG49422.1 - 0.43 10.6 5.9 7.9 6.5 0.5 3.0 3 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand eIF-1a PF01176.19 EMG49423.1 - 4.3e-20 71.3 0.1 6e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Mg_trans_NIPA PF05653.14 EMG49424.1 - 7.4e-106 353.6 16.6 8.8e-106 353.3 16.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EMG49424.1 - 9.1e-05 22.7 6.6 9.1e-05 22.7 6.6 3.3 3 0 0 3 3 3 1 EamA-like transporter family DUF1282 PF06930.12 EMG49424.1 - 0.2 11.4 18.2 0.035 13.9 7.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) DUF5381 PF17353.2 EMG49424.1 - 0.43 10.3 7.2 0.14 11.9 0.6 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5381) Saf_2TM PF18303.1 EMG49424.1 - 1.4 8.5 4.9 2.3 7.8 0.3 2.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain MARVEL PF01284.23 EMG49424.1 - 1.5 8.8 13.0 6.5 6.8 12.5 2.3 1 1 0 1 1 1 0 Membrane-associating domain Gal4_dimer PF03902.13 EMG49425.1 - 6.2e-19 67.9 1.6 2.1e-18 66.2 1.6 2.0 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.18 EMG49425.1 - 3.8e-07 30.1 17.9 6.5e-07 29.4 17.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL34 PF15036.6 EMG49426.1 - 0.23 11.5 2.1 0.24 11.4 0.0 2.1 3 0 0 3 3 3 0 Interleukin 34 RabGAP-TBC PF00566.18 EMG49427.1 - 1.1e-46 159.3 3.9 1.1e-46 159.3 3.9 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GIT_CC PF16559.5 EMG49427.1 - 0.00035 20.4 11.3 0.78 9.7 0.2 3.6 2 1 1 3 3 3 3 GIT coiled-coil Rho guanine nucleotide exchange factor APG6_N PF17675.1 EMG49427.1 - 0.02 15.4 0.2 0.02 15.4 0.2 3.2 3 1 1 4 4 4 0 Apg6 coiled-coil region YabA PF06156.13 EMG49427.1 - 0.031 14.9 2.4 0.031 14.9 2.4 4.1 2 1 2 4 4 4 0 Initiation control protein YabA Phage_Nu1 PF07471.12 EMG49427.1 - 0.33 10.7 2.6 16 5.2 0.5 2.4 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 Seryl_tRNA_N PF02403.22 EMG49427.1 - 2.1 8.6 18.3 0.24 11.6 2.4 3.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Filament PF00038.21 EMG49427.1 - 2.4 7.7 17.9 0.32 10.5 9.8 2.4 2 1 0 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 EMG49427.1 - 3.2 7.8 16.5 0.045 13.8 2.2 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 EMG49427.1 - 9.6 5.2 10.2 0.53 9.3 2.7 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RQC PF09382.10 EMG49428.1 - 1.4e-23 82.8 0.3 3.4e-23 81.6 0.3 1.7 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 EMG49428.1 - 2.9e-21 76.0 0.0 9e-21 74.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG49428.1 - 1.6e-20 73.5 0.0 5.8e-16 58.8 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EMG49428.1 - 3.6e-16 59.6 8.8 1e-15 58.2 7.8 2.4 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 EMG49428.1 - 7.8e-06 26.0 0.0 2.8e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IpaB_EvcA PF03278.13 EMG49428.1 - 0.0036 17.0 0.2 0.013 15.3 0.2 1.9 1 0 0 1 1 1 1 IpaB/EvcA family Fes1 PF08609.10 EMG49428.1 - 0.096 13.6 0.1 0.096 13.6 0.1 2.4 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Rhodanese PF00581.20 EMG49428.1 - 0.13 12.8 2.0 4.3 7.9 0.1 3.4 2 1 1 3 3 3 0 Rhodanese-like domain UQ_con PF00179.26 EMG49429.1 - 3.5e-22 78.6 0.2 4.4e-22 78.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMG49429.1 - 0.013 15.1 0.1 0.019 14.7 0.1 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B Med13_N PF11597.8 EMG49429.1 - 0.045 13.1 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal zf-CCCH PF00642.24 EMG49430.1 - 1e-20 73.1 15.3 1.3e-12 47.3 1.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EMG49430.1 - 5.6e-08 32.6 21.1 4.1e-06 26.7 2.1 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EMG49430.1 - 5.8e-08 32.4 16.1 4.4e-05 23.2 0.8 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EMG49430.1 - 0.12 12.9 1.2 0.12 12.9 1.2 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EMG49430.1 - 9.4 7.0 17.7 0.1 13.3 1.4 2.7 2 1 1 3 3 3 0 Torus domain zf-H2C2_2 PF13465.6 EMG49431.1 - 9e-11 41.7 18.2 2e-06 28.0 3.3 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EMG49431.1 - 2.6e-08 33.9 16.7 0.00037 20.8 7.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG49431.1 - 6.1e-05 23.5 13.7 0.034 15.0 5.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMG49431.1 - 0.0083 16.4 4.6 0.033 14.5 1.9 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EMG49431.1 - 0.028 14.7 1.4 0.028 14.7 1.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 EMG49431.1 - 0.037 14.7 3.8 0.13 12.9 0.1 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 EMG49431.1 - 0.069 12.9 17.3 1.1 9.0 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EMG49431.1 - 0.096 12.7 2.7 5.3 7.2 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 EMG49431.1 - 0.11 12.8 5.6 0.19 12.1 5.6 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.12 EMG49431.1 - 0.63 10.1 3.2 1.5 8.9 3.2 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger HEAT PF02985.22 EMG49432.1 - 2.2e-30 102.1 9.2 0.048 13.9 0.0 14.3 15 0 0 15 15 14 8 HEAT repeat HEAT_EZ PF13513.6 EMG49432.1 - 7.2e-27 93.4 18.3 0.016 15.7 0.1 13.5 14 1 1 15 15 11 7 HEAT-like repeat HEAT_2 PF13646.6 EMG49432.1 - 2.1e-21 76.1 19.9 0.0025 18.1 0.1 13.2 12 2 1 14 14 14 5 HEAT repeats CLASP_N PF12348.8 EMG49432.1 - 1.3e-16 60.8 1.8 0.0078 15.8 0.0 9.8 8 3 4 12 12 12 4 CLASP N terminal Gcn1_N PF12074.8 EMG49432.1 - 2.6e-16 59.9 17.9 1.4e-13 50.9 0.1 6.4 6 1 1 7 7 7 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Vac14_Fab1_bd PF12755.7 EMG49432.1 - 5e-13 49.5 0.0 0.054 14.1 0.0 8.2 7 2 0 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EMG49432.1 - 3.5e-12 46.7 19.1 0.18 11.8 0.2 11.2 7 5 4 12 12 12 3 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 EMG49432.1 - 0.0015 18.9 0.4 1.6 9.1 0.0 5.5 7 0 0 7 7 7 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Atx10homo_assoc PF09759.9 EMG49432.1 - 0.0048 16.9 0.2 0.092 12.8 0.0 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Tti2 PF10521.9 EMG49432.1 - 0.0056 16.3 0.7 0.61 9.6 0.0 4.1 3 1 1 4 4 4 1 Tti2 family NUC173 PF08161.12 EMG49432.1 - 0.034 13.8 2.7 12 5.4 0.0 5.0 5 0 0 5 5 5 0 NUC173 domain RTP1_C1 PF10363.9 EMG49432.1 - 0.039 14.1 6.4 45 4.3 0.2 6.0 6 1 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 EMG49432.1 - 0.1 12.3 4.4 8.1 6.1 0.1 5.4 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis U3snoRNP10 PF12397.8 EMG49432.1 - 3.4 8.0 14.3 2.3 8.6 1.4 5.7 6 0 0 6 6 6 0 U3 small nucleolar RNA-associated protein 10 Pkinase PF00069.25 EMG49433.1 - 1.7e-60 204.7 0.5 1.7e-60 204.7 0.5 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49433.1 - 5.7e-37 127.4 0.0 6.9e-36 123.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Bacillus_HBL PF05791.11 EMG49433.1 - 0.0015 18.4 1.4 0.0035 17.2 1.4 1.6 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) Pkinase_fungal PF17667.1 EMG49433.1 - 0.027 13.3 1.8 0.083 11.6 0.0 2.3 3 0 0 3 3 3 0 Fungal protein kinase Exonuc_VII_L PF02601.15 EMG49433.1 - 0.098 12.2 6.9 0.14 11.7 6.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HMMR_N PF15905.5 EMG49433.1 - 0.6 9.5 23.4 0.064 12.7 19.0 1.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Emaravirus_P4 PF16505.5 EMG49433.1 - 2.9 6.8 5.8 4.7 6.1 5.8 1.2 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily DUF2207 PF09972.9 EMG49433.1 - 3.8 6.2 6.9 13 4.4 4.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FH2 PF02181.23 EMG49434.1 - 3.7e-89 299.5 8.8 3.7e-89 299.5 8.8 2.9 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 EMG49434.1 - 1.1e-51 175.2 1.1 1.1e-51 175.2 1.1 4.0 3 1 0 3 3 3 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 EMG49434.1 - 2.4e-35 121.8 0.3 2.4e-35 121.8 0.3 3.6 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain Sugar_tr PF00083.24 EMG49435.1 - 8.7e-44 150.1 22.4 1.2e-43 149.7 22.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG49435.1 - 4.5e-09 35.7 15.7 4.5e-09 35.7 15.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily SK_channel PF03530.14 EMG49435.1 - 0.34 10.9 6.6 2.2 8.3 1.2 2.9 2 1 0 2 2 2 0 Calcium-activated SK potassium channel MMS1_N PF10433.9 EMG49436.1 - 5.3e-53 180.4 2.1 5.3e-53 180.4 2.1 2.6 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Speriolin_N PF15058.6 EMG49437.1 - 0.24 11.5 0.7 0.26 11.3 0.7 1.1 1 0 0 1 1 1 0 Speriolin N terminus NYD-SP28_assoc PF14775.6 EMG49437.1 - 2.1 8.5 6.9 7.5 6.7 2.7 2.6 1 1 2 3 3 3 0 Sperm tail C-terminal domain Yip1 PF04893.17 EMG49438.1 - 8.6e-07 28.8 6.3 1.2e-06 28.4 6.3 1.2 1 0 0 1 1 1 1 Yip1 domain DUF3337 PF11816.8 EMG49439.1 - 3.6e-38 131.1 1.4 9.5e-38 129.8 0.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EMG49439.1 - 5.3e-12 46.1 22.4 0.0002 22.1 0.1 7.9 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG49439.1 - 0.012 15.9 0.1 19 5.6 0.0 4.5 3 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain CENP-S PF15630.6 EMG49440.1 - 5.2e-24 84.4 0.1 1.1e-23 83.3 0.1 1.5 1 1 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EMG49440.1 - 3.1e-06 27.3 0.0 4.6e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EMG49440.1 - 0.021 15.2 0.1 0.023 15.0 0.1 1.1 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EMG49440.1 - 0.084 13.0 0.2 0.27 11.3 0.1 1.8 1 1 1 2 2 2 0 Transcription initiation factor IID, 31kD subunit Mitochondr_Som1 PF11093.8 EMG49441.1 - 1.3e-26 92.4 0.6 1.8e-26 92.0 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 BCIP PF13862.6 EMG49442.1 - 3.3e-65 219.7 6.0 4.6e-65 219.3 6.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PCI PF01399.27 EMG49443.1 - 8.8e-11 42.2 0.5 8.8e-11 42.2 0.5 2.9 3 0 0 3 3 3 1 PCI domain MAD PF05557.13 EMG49444.1 - 2.4e-20 72.5 81.7 2.4e-20 72.5 81.7 2.1 1 1 1 2 2 2 2 Mitotic checkpoint protein XhlA PF10779.9 EMG49444.1 - 0.029 14.5 1.0 0.029 14.5 1.0 9.2 7 2 2 9 9 9 0 Haemolysin XhlA SlyX PF04102.12 EMG49444.1 - 0.15 12.7 0.2 0.15 12.7 0.2 8.8 7 3 3 10 10 10 0 SlyX APC_N_CC PF16689.5 EMG49444.1 - 5.2 7.2 40.5 0.07 13.2 0.8 7.1 6 0 0 6 6 6 0 Coiled-coil N-terminus of APC, dimerisation domain MbeD_MobD PF04899.12 EMG49444.1 - 6.3 7.0 42.2 2.2 8.4 3.8 7.6 5 3 2 7 7 7 0 MbeD/MobD like PRP1_N PF06424.12 EMG49445.1 - 7.1e-28 97.9 2.1 1.3e-27 97.1 0.7 2.2 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EMG49445.1 - 2.3e-18 65.3 0.1 0.14 13.0 0.0 10.3 5 3 6 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMG49445.1 - 1.3e-12 48.0 0.0 0.0014 19.1 0.0 7.7 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMG49445.1 - 1.1e-06 28.2 5.5 12 6.3 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMG49445.1 - 1.8e-06 27.7 0.6 9.3 6.8 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMG49445.1 - 0.00012 22.2 11.1 6.2 7.4 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMG49445.1 - 0.00016 22.2 0.0 0.8 10.4 0.0 4.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EMG49445.1 - 0.00029 20.1 7.5 0.06 12.5 0.1 3.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EMG49445.1 - 0.0011 19.1 0.0 1.3 9.2 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMG49445.1 - 0.048 13.3 0.8 7.4 6.3 0.1 4.2 5 0 0 5 5 5 0 TPR repeat TPR_1 PF00515.28 EMG49445.1 - 8.5 6.4 8.4 18 5.3 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat CAF1C_H4-bd PF12265.8 EMG49446.1 - 4.5e-15 55.7 0.0 1.4e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EMG49446.1 - 1.1e-12 48.2 10.5 0.0036 18.1 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG49446.1 - 5.4e-07 29.8 1.2 0.065 13.5 0.2 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain ELH PF02323.15 EMG49446.1 - 0.086 12.2 4.6 0.1 11.9 0.1 2.3 2 0 0 2 2 2 0 Egg-laying hormone precursor TFIIF_alpha PF05793.12 EMG49446.1 - 5.2 5.5 28.3 6.7 5.2 20.8 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pro_isomerase PF00160.21 EMG49447.1 - 1.9e-44 151.7 0.4 3.4e-44 150.9 0.4 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ge1_WD40 PF16529.5 EMG49447.1 - 4.1e-05 22.7 0.0 0.00012 21.2 0.0 1.7 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein EAF PF09816.9 EMG49448.1 - 5e-21 75.0 0.8 5e-21 75.0 0.8 2.3 3 0 0 3 3 3 1 RNA polymerase II transcription elongation factor BAR PF03114.18 EMG49449.1 - 6.2e-42 143.9 10.0 8.5e-42 143.4 10.0 1.2 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EMG49449.1 - 0.0012 18.6 11.5 0.0014 18.4 10.3 1.6 1 1 1 2 2 2 1 BAR domain of APPL family Arfaptin PF06456.13 EMG49449.1 - 0.026 14.1 0.5 0.026 14.1 0.5 2.4 3 0 0 3 3 3 0 Arfaptin-like domain NPV_P10 PF05531.12 EMG49449.1 - 0.37 11.3 9.4 1.1 9.8 1.1 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF241 PF03087.14 EMG49449.1 - 1.6 8.5 7.3 4.6 7.0 3.4 2.7 2 1 0 2 2 2 0 Arabidopsis protein of unknown function Uds1 PF15456.6 EMG49449.1 - 5.2 7.3 9.8 6.8 6.9 6.2 2.5 2 1 0 2 2 2 0 Up-regulated During Septation UCH_1 PF13423.6 EMG49450.1 - 2.4e-10 40.5 0.0 0.00073 19.2 0.0 2.6 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase HSP20 PF00011.21 EMG49450.1 - 0.57 10.4 3.4 13 6.0 0.5 2.7 2 0 0 2 2 2 0 Hsp20/alpha crystallin family WD40 PF00400.32 EMG49451.1 - 8e-24 83.5 5.5 1.1e-05 26.0 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG49451.1 - 1.2e-10 41.5 0.0 0.00015 22.0 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EMG49451.1 - 0.0016 17.5 0.1 0.38 9.7 0.0 2.4 2 0 0 2 2 2 2 Coatomer WD associated region ELO PF01151.18 EMG49452.1 - 1.2e-58 198.6 27.7 1.5e-58 198.3 27.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RNA_pol_Rpb5_C PF01191.19 EMG49453.1 - 1.5e-32 111.3 0.4 3.1e-32 110.3 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EMG49453.1 - 6.4e-29 100.4 0.1 1.1e-28 99.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.14 EMG49453.1 - 0.08 13.2 0.3 0.15 12.3 0.3 1.4 1 0 0 1 1 1 0 Sof1-like domain SH3_2 PF07653.17 EMG49453.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain MFAP1 PF06991.11 EMG49454.1 - 4.7e-15 56.0 13.6 2e-14 54.0 13.6 1.7 1 1 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing GIT_SHD PF08518.11 EMG49455.1 - 8.6e-25 86.1 5.8 2.9e-13 49.2 0.8 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 EMG49455.1 - 3.1e-05 24.1 1.1 3.1e-05 24.1 1.1 3.2 3 0 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term DUF4201 PF13870.6 EMG49455.1 - 0.0072 16.1 10.9 0.0072 16.1 10.9 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) Cep57_CLD_2 PF14197.6 EMG49455.1 - 5 7.3 12.8 1.5 9.0 2.5 4.3 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Cwf_Cwc_15 PF04889.12 EMG49456.1 - 1e-20 74.6 34.6 2e-08 34.3 5.3 3.0 1 1 1 3 3 3 3 Cwf15/Cwc15 cell cycle control protein Tho2 PF11262.8 EMG49456.1 - 0.11 11.6 9.3 0.15 11.2 9.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Hyphal_reg_CWP PF11765.8 EMG49457.1 - 3e-80 269.6 10.7 3e-80 269.6 10.7 1.6 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal DEAD PF00270.29 EMG49458.1 - 1.4e-41 142.1 0.5 3.5e-41 140.9 0.5 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG49458.1 - 5.5e-31 107.2 5.8 5.5e-30 104.0 0.1 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EMG49458.1 - 0.015 15.6 0.8 0.12 12.6 0.8 2.4 1 1 0 1 1 1 0 AAA domain Ribonucleas_3_3 PF14622.6 EMG49459.1 - 1.2e-23 83.6 0.0 1.7e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Serinc PF03348.15 EMG49461.1 - 1.1e-144 482.5 17.6 1.3e-144 482.3 17.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3566 PF12089.8 EMG49461.1 - 0.048 14.0 0.3 0.048 14.0 0.3 2.7 2 1 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) Mpv17_PMP22 PF04117.12 EMG49461.1 - 7 7.0 10.1 0.33 11.2 2.8 2.5 2 0 0 2 2 2 0 Mpv17 / PMP22 family ATP-synt_G PF04718.15 EMG49462.1 - 1.2e-21 77.4 0.3 1.5e-21 77.1 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit SCAB-Ig PF16709.5 EMG49462.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein Rax2 PF12768.7 EMG49463.1 - 1e-61 208.1 0.3 1e-61 208.1 0.3 5.2 4 1 0 5 5 5 2 Cortical protein marker for cell polarity VTC PF09359.10 EMG49463.1 - 0.0087 15.5 2.7 1.2 8.4 0.1 2.6 2 0 0 2 2 2 2 VTC domain Cu_amine_oxidN1 PF07833.11 EMG49463.1 - 0.078 13.5 0.4 0.38 11.3 0.1 2.3 2 0 0 2 2 2 0 Copper amine oxidase N-terminal domain TRAPPC-Trs85 PF12739.7 EMG49464.1 - 2.1e-101 339.8 9.7 2.1e-101 339.8 9.7 1.4 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF1751 PF08551.10 EMG49465.1 - 1.9e-20 73.3 2.9 1.9e-20 73.3 2.9 2.2 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EMG49465.1 - 0.00012 22.2 9.1 0.00022 21.3 9.1 1.5 1 1 0 1 1 1 1 Rhomboid family RseC_MucC PF04246.12 EMG49465.1 - 2.2 8.3 4.2 0.41 10.6 0.3 1.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF5321 PF17254.2 EMG49466.1 - 4.4e-10 39.2 4.9 1.5e-09 37.5 4.9 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5321) PdaC PF13739.6 EMG49466.1 - 3.7 8.6 6.3 8.3 7.5 6.3 1.7 1 1 0 1 1 1 0 Deacetylase PdaC MCM PF00493.23 EMG49467.1 - 9.1e-102 338.9 0.0 1.4e-101 338.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMG49467.1 - 2.5e-37 127.5 0.5 5e-37 126.6 0.5 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EMG49467.1 - 7.9e-29 99.9 2.5 2.2e-28 98.5 2.5 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMG49467.1 - 9.3e-17 61.5 2.5 2.6e-16 60.1 1.9 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMG49467.1 - 6e-06 25.8 0.0 0.00022 20.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMG49467.1 - 1.2e-05 25.3 0.0 4.7e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EMG49467.1 - 0.00042 20.2 0.0 0.0043 16.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMG49467.1 - 0.068 12.9 0.3 2.8 7.6 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Rad51 PF08423.11 EMG49468.1 - 8.9e-116 385.6 0.3 1.4e-115 385.0 0.0 1.4 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 EMG49468.1 - 3.1e-11 43.2 0.0 4.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EMG49468.1 - 1.3e-08 34.5 0.0 2.8e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 EMG49468.1 - 9.9e-06 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 EMG49468.1 - 3.1e-05 24.5 2.5 5.4e-05 23.7 0.9 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.15 EMG49468.1 - 0.0032 17.2 0.3 0.0086 15.8 0.3 1.7 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain NRD1_2 PF01995.16 EMG49468.1 - 0.0045 16.3 0.3 0.0075 15.6 0.3 1.2 1 0 0 1 1 1 1 NrpR regulatory domains NRD1 and 2 AAA_22 PF13401.6 EMG49468.1 - 0.035 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 EMG49469.1 - 8.1e-101 337.8 0.6 1e-100 337.5 0.6 1.0 1 0 0 1 1 1 1 PAXNEB protein Sortilin-Vps10 PF15902.5 EMG49471.1 - 2.2e-241 801.3 6.2 9.6e-135 449.8 0.0 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EMG49471.1 - 2.7e-75 252.4 20.6 2e-44 151.9 3.5 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EMG49471.1 - 1.7e-13 48.4 39.7 0.019 14.9 0.4 11.3 12 0 0 12 12 12 6 BNR/Asp-box repeat PSII_BNR PF14870.6 EMG49471.1 - 3.3e-08 33.2 0.1 0.051 12.8 0.0 4.8 4 1 0 4 4 4 3 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 EMG49471.1 - 2.1e-07 30.6 0.0 0.23 10.7 0.0 5.8 5 3 0 5 5 5 2 BNR repeat-like domain CHB_HEX_C PF03174.13 EMG49471.1 - 0.12 12.4 0.6 23 5.1 0.0 3.8 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain preSET_CXC PF18264.1 EMG49471.1 - 3.4 8.2 8.3 17 6.0 1.8 2.6 2 0 0 2 2 2 0 CXC domain Ribosomal_L27e PF01777.18 EMG49472.1 - 2.4e-26 91.9 11.9 2.4e-26 91.9 11.9 2.2 2 0 0 2 2 2 1 Ribosomal L27e protein family tRNA-synt_1b PF00579.25 EMG49472.1 - 1.4e-15 57.4 0.7 5.8e-10 39.0 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (W and Y) KOW PF00467.29 EMG49472.1 - 0.0023 17.8 1.2 0.0064 16.4 1.2 1.8 1 0 0 1 1 1 1 KOW motif Pkinase PF00069.25 EMG49473.1 - 1.6e-65 221.1 0.1 1.6e-65 221.1 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49473.1 - 1.8e-34 119.2 0.0 2.7e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG49473.1 - 1e-06 28.3 0.1 4e-06 26.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EMG49473.1 - 3.2e-05 23.4 0.1 6.8e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMG49473.1 - 0.001 18.1 0.2 0.001 18.1 0.2 2.5 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 EMG49473.1 - 0.0052 16.4 1.2 2.4 7.7 0.1 2.7 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EMG49473.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EMG49473.1 - 0.016 14.8 0.3 0.039 13.6 0.3 1.6 1 0 0 1 1 1 0 RIO1 family HEPN_AbiU2 PF18734.1 EMG49473.1 - 0.041 13.4 5.3 0.11 12.0 5.3 1.7 1 0 0 1 1 1 0 AbiU2 CRIM PF16978.5 EMG49474.1 - 3e-27 95.5 0.0 1.3e-26 93.5 0.0 2.2 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain RNase_T PF00929.24 EMG49474.1 - 3.2e-13 50.5 0.0 1.2e-12 48.7 0.0 2.1 1 0 0 1 1 1 1 Exonuclease SIN1_PH PF16979.5 EMG49474.1 - 1.9e-05 24.9 4.1 0.00024 21.3 3.1 3.4 2 1 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology tRNA-synt_1c_C PF03950.18 EMG49474.1 - 0.26 11.1 3.3 17 5.3 0.7 2.9 1 1 1 2 2 2 0 tRNA synthetases class I (E and Q), anti-codon binding domain RasGAP PF00616.19 EMG49475.1 - 4.2e-26 91.9 10.5 2e-18 66.9 0.1 4.7 4 1 1 5 5 5 2 GTPase-activator protein for Ras-like GTPase Desmo_N PF06771.11 EMG49475.1 - 0.083 13.3 2.2 2.1 8.8 0.0 3.9 3 0 0 3 3 3 0 Viral Desmoplakin N-terminus Brix PF04427.18 EMG49477.1 - 6.2e-41 140.6 0.3 8.2e-41 140.2 0.3 1.2 1 0 0 1 1 1 1 Brix domain ATP19 PF11022.8 EMG49478.1 - 1.8e-21 76.3 0.0 2e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K RNB PF00773.19 EMG49480.1 - 2.1e-99 333.0 0.1 3.1e-99 332.4 0.1 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 EMG49480.1 - 2.5e-46 157.0 0.2 6.2e-46 155.8 0.2 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EMG49480.1 - 1.3e-29 102.0 3.1 3.7e-29 100.5 3.1 1.8 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 EMG49480.1 - 2.8e-20 72.1 0.0 6.9e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EMG49480.1 - 3.2e-18 66.3 0.6 7.4e-18 65.1 0.6 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 EMG49480.1 - 2.7e-06 27.4 0.0 0.00011 22.2 0.0 3.0 2 0 0 2 2 2 1 Cold shock domain Dis3l2_C_term PF17877.1 EMG49480.1 - 0.044 14.1 0.4 0.13 12.6 0.4 1.8 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Mss4 PF04421.13 EMG49480.1 - 0.09 12.9 0.0 33 4.7 0.0 3.0 2 0 0 2 2 2 0 Mss4 protein DHBP_synthase PF00926.19 EMG49481.1 - 2.3e-85 285.0 0.0 2.5e-85 284.8 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Prenyltransf PF01255.19 EMG49482.1 - 4.8e-70 235.6 0.1 1.2e-69 234.2 0.0 1.7 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Vma12 PF11712.8 EMG49482.1 - 4.7e-40 136.9 1.2 1e-39 135.8 1.2 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP-synt_I PF03899.15 EMG49482.1 - 0.066 13.6 4.9 0.13 12.6 4.9 1.5 1 0 0 1 1 1 0 ATP synthase I chain OAD_gamma PF04277.13 EMG49482.1 - 0.54 10.9 2.6 0.59 10.8 0.5 2.2 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_L50 PF10501.9 EMG49483.1 - 5.2e-31 107.0 0.0 1.6e-30 105.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal subunit 39S Catalase-rel PF06628.12 EMG49483.1 - 0.056 13.7 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Catalase-related immune-responsive Rhomboid PF01694.22 EMG49484.1 - 1.6e-27 96.4 13.0 1.6e-27 96.4 13.0 1.8 2 0 0 2 2 2 1 Rhomboid family K1 PF02960.14 EMG49484.1 - 0.36 10.9 3.1 0.89 9.7 0.2 2.7 2 0 0 2 2 2 0 K1 glycoprotein Trypan_PARP PF05887.11 EMG49484.1 - 1.4 8.9 4.5 3.1 7.8 4.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 EMG49484.1 - 7.1 5.0 12.7 11 4.3 12.7 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein E1-E2_ATPase PF00122.20 EMG49485.1 - 2.1e-48 164.3 0.2 9.2e-48 162.1 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMG49485.1 - 7.5e-38 130.9 1.3 2.5e-37 129.2 0.6 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EMG49485.1 - 6.3e-20 71.4 7.0 5.7e-09 36.3 0.1 5.2 4 1 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.7 EMG49485.1 - 6.7e-05 23.4 0.0 0.00014 22.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMG49485.1 - 0.025 14.3 8.6 0.26 11.0 0.2 3.3 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase ATP-grasp PF02222.22 EMG49485.1 - 0.047 13.3 0.3 0.19 11.3 0.0 2.1 3 0 0 3 3 3 0 ATP-grasp domain HAD_2 PF13419.6 EMG49485.1 - 0.086 12.9 0.1 0.31 11.1 0.1 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zf-AD PF07776.15 EMG49485.1 - 7.7 6.8 6.3 0.77 10.1 0.8 2.3 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) tRNA_SAD PF07973.14 EMG49486.1 - 8e-11 41.9 0.1 2.6e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 EMG49486.1 - 2.1e-07 29.9 0.0 3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) Penicillinase_R PF03965.16 EMG49486.1 - 0.019 15.3 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 Penicillinase repressor CBS PF00571.28 EMG49487.1 - 2.1e-32 111.3 8.5 1.4e-08 35.0 0.1 5.7 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 EMG49487.1 - 9.4e-08 31.9 0.1 1.8e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 PB1 domain BAR_3 PF16746.5 EMG49487.1 - 0.095 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 BAR domain of APPL family RMI1_N PF08585.12 EMG49487.1 - 1.3 8.7 8.6 0.11 12.2 1.7 2.6 2 1 1 3 3 3 0 RecQ mediated genome instability protein PP2C PF00481.21 EMG49488.1 - 2.9e-66 223.8 0.0 2.3e-65 220.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Ustilago_mating PF05722.12 EMG49488.1 - 2.2 7.7 7.9 3.4 7.1 7.9 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein RAP1 PF07218.11 EMG49488.1 - 3.2 5.9 8.9 4.3 5.5 8.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) F-box-like PF12937.7 EMG49489.1 - 3.2e-06 26.9 0.2 7.3e-06 25.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMG49489.1 - 0.087 12.7 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 F-box domain DnaJ PF00226.31 EMG49490.1 - 2.8e-16 59.4 1.4 2.8e-16 59.4 1.4 2.7 3 0 0 3 3 3 1 DnaJ domain PigN PF04987.14 EMG49491.1 - 6.8e-138 460.3 44.1 9.7e-138 459.8 44.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) IGPS PF00218.21 EMG49491.1 - 7.8e-77 257.9 0.1 1.2e-76 257.3 0.1 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 EMG49491.1 - 6.4e-42 143.5 0.5 1.1e-41 142.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Phosphodiest PF01663.22 EMG49491.1 - 1.6e-10 41.2 0.1 1e-08 35.2 0.1 2.3 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMG49491.1 - 1.7e-08 34.2 0.0 6.2e-08 32.4 0.0 1.8 1 1 1 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 EMG49491.1 - 4.1e-06 26.4 0.0 6.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Peptidase_C26 PF07722.13 EMG49491.1 - 5.9e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 MFS_1 PF07690.16 EMG49492.1 - 3.9e-35 121.4 33.6 3.9e-35 121.4 33.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMG49492.1 - 1e-05 24.2 5.7 1.7e-05 23.5 5.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EMG49492.1 - 0.00028 19.4 5.3 0.00044 18.8 5.3 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector AAA_22 PF13401.6 EMG49493.1 - 5e-13 49.5 0.2 1.4e-12 48.1 0.2 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EMG49493.1 - 2e-11 44.4 0.1 4.9e-11 43.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMG49493.1 - 2e-09 38.1 0.8 1.8e-07 31.7 0.8 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 EMG49493.1 - 8.3e-06 25.9 0.1 2.1e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 EMG49493.1 - 0.00044 20.6 0.0 0.0012 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EMG49493.1 - 0.00069 19.1 0.1 0.0017 17.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial TniB protein Sigma54_activat PF00158.26 EMG49493.1 - 0.0011 18.7 0.4 0.044 13.5 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SSE PF00437.20 EMG49493.1 - 0.0013 17.9 0.1 0.0035 16.4 0.1 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_11 PF13086.6 EMG49493.1 - 0.0027 17.5 0.2 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 EMG49493.1 - 0.0044 16.3 0.4 1.7 7.8 0.0 2.5 1 1 1 2 2 2 2 KAP family P-loop domain Cdc6_C PF09079.11 EMG49493.1 - 0.0045 16.9 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain Rad17 PF03215.15 EMG49493.1 - 0.006 16.5 1.1 0.017 15.1 1.1 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_7 PF12775.7 EMG49493.1 - 0.0096 15.4 0.1 0.32 10.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 EMG49493.1 - 0.0096 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EMG49493.1 - 0.032 14.2 0.2 0.13 12.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMG49493.1 - 0.074 13.2 0.0 3.6 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Myb_DNA-binding PF00249.31 EMG49494.1 - 4.7e-13 49.1 0.0 2.1e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Nop14 PF04147.12 EMG49494.1 - 0.00074 17.9 22.8 0.0013 17.0 22.8 1.3 1 0 0 1 1 1 1 Nop14-like family WRNPLPNID PF15017.6 EMG49494.1 - 0.42 11.5 0.0 0.42 11.5 0.0 4.3 4 1 0 4 4 4 0 Putative WW-binding domain and destruction box Ribosomal_S9 PF00380.19 EMG49495.1 - 1.1e-41 142.1 0.2 2e-41 141.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AAA_lid_7 PF17867.1 EMG49495.1 - 0.026 14.7 0.1 0.048 13.9 0.1 1.4 1 0 0 1 1 1 0 Midasin AAA lid domain EF-hand_4 PF12763.7 EMG49496.1 - 7.2e-33 112.6 0.0 2.8e-11 43.3 0.2 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 EMG49496.1 - 1.4e-11 44.0 0.4 3e-11 43.0 0.4 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 EMG49496.1 - 0.0003 20.5 0.4 0.17 11.9 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 EMG49496.1 - 0.00056 19.3 0.0 3.5 7.4 0.0 4.3 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 EMG49496.1 - 0.00081 19.8 0.0 0.64 10.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair UBA_4 PF14555.6 EMG49496.1 - 0.0037 17.0 0.1 0.008 16.0 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 EMG49496.1 - 0.0068 16.1 0.1 0.019 14.7 0.1 1.8 1 0 0 1 1 1 1 CUE domain MADF_DNA_bdg PF10545.9 EMG49496.1 - 0.022 15.1 0.9 0.066 13.5 0.9 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4201 PF13870.6 EMG49496.1 - 0.054 13.2 31.7 0.022 14.5 14.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) COG2 PF06148.11 EMG49496.1 - 1 9.4 24.3 1.6 8.8 4.2 3.4 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Tup_N PF08581.10 EMG49496.1 - 1.3 9.4 20.8 0.062 13.6 3.6 4.4 2 1 3 5 5 5 0 Tup N-terminal TauD PF02668.16 EMG49497.1 - 2.6e-50 171.7 0.6 3.4e-50 171.3 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.18 EMG49498.1 - 0.00028 21.0 13.9 0.00028 21.0 13.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_1 PF00018.28 EMG49499.1 - 1.6e-08 34.0 0.0 3.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMG49499.1 - 2.8e-06 27.1 0.0 1.5e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 Variant SH3 domain DUF4448 PF14610.6 EMG49499.1 - 0.0013 18.6 0.3 0.0057 16.5 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 EMG49499.1 - 0.0024 17.8 1.2 0.0024 17.8 1.2 2.2 1 1 1 2 2 2 1 TMEM154 protein family SH3_3 PF08239.11 EMG49499.1 - 0.0098 16.2 0.3 0.039 14.2 0.1 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain SKG6 PF08693.10 EMG49499.1 - 0.028 13.8 0.1 0.061 12.7 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Abhydrolase_1 PF00561.20 EMG49501.1 - 1.2e-43 149.7 0.0 1.6e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EMG49501.1 - 0.00021 21.0 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EMG49501.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PLDc PF00614.22 EMG49502.1 - 1.8e-15 56.3 0.1 5.8e-08 32.6 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EMG49502.1 - 3.5e-12 46.4 0.3 1.9e-07 31.0 0.1 2.9 2 1 0 2 2 2 2 PLD-like domain DOPA_dioxygen PF08883.11 EMG49503.1 - 9.2e-37 125.5 0.2 1e-36 125.3 0.2 1.0 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family VanZ PF04892.12 EMG49504.1 - 1.2e-08 35.7 4.7 1.8e-08 35.1 4.7 1.3 1 0 0 1 1 1 1 VanZ like family FAM176 PF14851.6 EMG49504.1 - 0.068 12.8 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 FAM176 family MMR_HSR1 PF01926.23 EMG49505.1 - 1.8e-17 63.4 0.5 9.8e-17 61.1 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMG49505.1 - 1.5e-07 31.1 0.1 4.2e-07 29.7 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EMG49505.1 - 2.7e-07 30.6 0.0 1.6e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EMG49505.1 - 2.3e-06 27.8 1.8 0.034 14.2 0.0 3.1 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 EMG49505.1 - 3.8e-06 26.4 0.1 2.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AIG1 family SRPRB PF09439.10 EMG49505.1 - 6.9e-06 25.6 0.4 2.9e-05 23.6 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EMG49505.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 EMG49505.1 - 0.0017 17.7 0.1 0.0042 16.4 0.1 1.7 1 0 0 1 1 1 1 Septin Roc PF08477.13 EMG49505.1 - 0.016 15.4 0.1 0.043 14.0 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EMG49505.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aa_trans PF01490.18 EMG49506.1 - 4e-85 286.0 29.7 5.2e-85 285.6 29.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 EMG49506.1 - 0.073 11.9 38.8 0.0068 15.3 33.2 1.7 1 1 1 2 2 2 0 Amino acid permease MitoNEET_N PF10660.9 EMG49506.1 - 0.26 11.4 4.2 0.19 11.8 0.3 2.7 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus PAP2 PF01569.21 EMG49507.1 - 1.8e-26 92.5 2.2 1.8e-26 92.5 2.2 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EMG49507.1 - 5 6.8 11.1 5e+02 0.2 10.8 3.1 1 1 0 1 1 1 0 PAP2 superfamily Sel1 PF08238.12 EMG49508.1 - 1.3e-14 54.3 9.8 0.0012 19.5 0.0 7.4 7 1 0 7 7 7 4 Sel1 repeat TPR_11 PF13414.6 EMG49508.1 - 0.00011 21.8 0.0 0.00011 21.8 0.0 3.4 4 1 1 5 5 5 1 TPR repeat TPR_17 PF13431.6 EMG49508.1 - 0.00036 20.7 0.9 0.0098 16.2 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMG49508.1 - 0.00039 20.1 10.1 0.019 14.8 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMG49508.1 - 0.00042 20.2 6.2 1.3 9.4 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMG49508.1 - 0.0007 19.4 0.3 0.89 9.7 0.1 3.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMG49508.1 - 0.019 15.1 10.7 2.6 8.5 0.7 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMG49508.1 - 0.1 13.5 0.0 8.9 7.4 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat NOA36 PF06524.12 EMG49508.1 - 0.14 11.5 18.3 0.018 14.4 6.5 2.4 2 0 0 2 2 2 0 NOA36 protein TPR_12 PF13424.6 EMG49508.1 - 3.4 8.0 7.6 0.7 10.2 0.1 3.8 5 1 0 5 5 4 0 Tetratricopeptide repeat Sigma70_ner PF04546.13 EMG49508.1 - 5.9 6.7 10.9 2.3 8.1 2.6 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region ADH_zinc_N PF00107.26 EMG49510.1 - 3.7e-10 39.9 0.0 5.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG49510.1 - 0.00074 19.4 0.1 0.0014 18.5 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMG49510.1 - 0.0027 18.7 0.0 0.0073 17.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase P4Ha_N PF08336.11 EMG49510.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region GATA PF00320.27 EMG49511.1 - 3.8e-15 55.2 4.6 7.6e-15 54.2 4.6 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EMG49511.1 - 0.008 15.7 1.0 0.022 14.3 1.0 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Elf1 PF05129.13 EMG49511.1 - 0.13 12.4 0.2 0.13 12.4 0.2 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Auto_anti-p27 PF06677.12 EMG49511.1 - 0.24 11.6 0.5 0.39 10.9 0.5 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1774 PF08611.10 EMG49512.1 - 1.3e-28 99.1 6.7 1.3e-28 99.1 6.7 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Pyridoxal_deC PF00282.19 EMG49513.1 - 2.6e-58 197.5 0.0 4e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EMG49513.1 - 5.7e-07 28.8 0.1 1.2e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V dCache_3 PF14827.6 EMG49513.1 - 0.039 13.6 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase DUF5076 PF16826.5 EMG49513.1 - 0.09 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5076) Topo_Zn_Ribbon PF08272.11 EMG49513.1 - 0.13 11.9 0.1 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like YebO PF13974.6 EMG49513.1 - 0.2 11.7 0.9 0.56 10.3 0.9 1.7 1 0 0 1 1 1 0 YebO-like protein NAC PF01849.18 EMG49514.1 - 5.5e-18 64.7 0.1 1.2e-17 63.6 0.1 1.6 1 0 0 1 1 1 1 NAC domain DUF3860 PF12976.7 EMG49514.1 - 0.087 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) DUF1779 PF08680.10 EMG49514.1 - 0.099 12.8 0.9 1.5 9.0 0.3 2.1 2 0 0 2 2 2 0 TATA-box binding XPC-binding PF09280.11 EMG49514.1 - 0.19 11.5 3.5 0.38 10.5 3.5 1.5 1 0 0 1 1 1 0 XPC-binding domain MFS_1 PF07690.16 EMG49515.1 - 3e-16 59.3 21.8 1.8e-10 40.3 9.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EMG49515.1 - 2.8e-11 43.4 10.4 2.8e-11 43.4 10.4 2.4 1 1 0 2 2 2 2 Nodulin-like PUCC PF03209.15 EMG49515.1 - 0.0017 17.5 2.2 0.0017 17.5 2.2 2.2 2 0 0 2 2 2 1 PUCC protein ApoO PF09769.9 EMG49516.1 - 2.9e-32 111.4 0.1 1.2e-31 109.4 0.0 1.8 2 0 0 2 2 2 1 Apolipoprotein O Ku PF02735.16 EMG49517.1 - 3.9e-28 98.5 2.4 2.9e-27 95.7 0.0 2.7 3 0 0 3 3 3 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 EMG49517.1 - 1.6e-05 25.5 1.4 1.6e-05 25.5 1.4 3.6 3 1 0 3 3 3 1 Ku70/Ku80 C-terminal arm Thymidylate_kin PF02223.17 EMG49518.1 - 1.9e-39 135.3 0.0 1.1e-38 132.8 0.0 1.9 1 1 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EMG49518.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EMG49518.1 - 0.0023 18.5 0.0 0.0095 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Ploopntkinase1 PF18748.1 EMG49518.1 - 0.057 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 ApbA_C PF08546.11 EMG49519.1 - 0.00014 22.0 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal CENP-H PF05837.12 EMG49519.1 - 4.5 7.7 14.9 1.5 9.2 11.4 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) AA_permease_2 PF13520.6 EMG49520.1 - 2.2e-77 260.7 51.1 2.6e-77 260.5 51.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG49520.1 - 1.3e-16 60.3 45.1 1.9e-16 59.8 45.1 1.1 1 0 0 1 1 1 1 Amino acid permease KH_1 PF00013.29 EMG49521.1 - 2.3e-76 251.5 51.0 1.2e-12 47.5 0.4 13.6 14 1 0 14 14 14 9 KH domain KH_4 PF13083.6 EMG49521.1 - 1.1e-05 25.3 5.9 1.3 8.9 0.1 5.9 5 0 0 5 5 5 2 KH domain KH_2 PF07650.17 EMG49521.1 - 1.3e-05 24.9 15.9 0.17 11.8 0.1 6.2 6 0 0 6 6 6 4 KH domain SLS PF14611.6 EMG49521.1 - 3.4e-05 23.8 28.5 0.012 15.4 2.2 6.5 4 3 3 7 7 7 3 Mitochondrial inner-membrane-bound regulator HTH_34 PF13601.6 EMG49521.1 - 0.11 12.6 0.0 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain Smg4_UPF3 PF03467.15 EMG49523.1 - 3e-18 66.5 48.2 2e-15 57.2 48.2 3.6 1 1 0 1 1 1 1 Smg-4/UPF3 family PCI PF01399.27 EMG49524.1 - 6.2e-07 29.9 2.1 3.5e-06 27.5 2.1 2.0 1 1 0 1 1 1 1 PCI domain Vta1 PF04652.16 EMG49525.1 - 4.2e-35 120.9 0.6 4.2e-35 120.9 0.6 1.8 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EMG49525.1 - 3.5e-15 55.4 0.5 7e-15 54.4 0.5 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain ABA_GPCR PF12430.8 EMG49525.1 - 0.055 13.2 0.2 0.084 12.6 0.2 1.2 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor Peptidase_S41_N PF11918.8 EMG49525.1 - 0.37 11.0 6.7 0.37 11.0 0.9 2.9 3 0 0 3 3 3 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP PH PF00169.29 EMG49526.1 - 8.8e-09 35.8 0.1 8e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 PH domain PI3K_1B_p101 PF10486.9 EMG49526.1 - 2 6.1 8.9 3.6 5.3 8.9 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Aa_trans PF01490.18 EMG49528.1 - 1.6e-83 280.7 36.5 1.9e-83 280.5 36.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein COX7a PF02238.15 EMG49528.1 - 0.19 12.2 1.6 0.27 11.7 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII AA_permease_2 PF13520.6 EMG49528.1 - 1.2 7.9 41.5 3.7 6.3 41.4 1.8 1 1 0 1 1 1 0 Amino acid permease LRR_8 PF13855.6 EMG49529.1 - 1.7e-07 30.9 19.6 9.3e-06 25.3 3.4 5.7 4 3 2 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 EMG49529.1 - 4.9e-06 26.8 35.5 0.013 15.9 0.6 8.8 4 3 5 9 9 9 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EMG49529.1 - 0.018 14.5 2.5 0.07 12.6 2.1 2.2 2 1 0 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 EMG49529.1 - 0.24 12.1 20.6 0.45 11.3 0.1 7.5 6 4 1 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 EMG49529.1 - 9 6.6 14.2 2.6 8.3 0.1 5.9 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 EMG49530.1 - 0.033 14.0 5.9 0.13 12.1 1.2 3.2 3 2 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 EMG49530.1 - 0.038 14.4 7.1 5.5 7.5 0.7 3.6 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) CMD PF02627.20 EMG49531.1 - 0.012 15.7 0.0 0.044 13.8 0.0 1.8 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Med10 PF09748.9 EMG49532.1 - 3.1e-38 130.4 0.1 3.6e-38 130.2 0.1 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex IMUP PF15761.5 EMG49533.1 - 2.9 8.6 12.2 1.7 9.3 3.5 2.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein Kinesin PF00225.23 EMG49534.1 - 1.2e-102 343.2 6.8 2.4e-102 342.3 6.8 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMG49534.1 - 6.3e-25 87.8 0.4 2e-24 86.2 0.4 1.9 1 0 0 1 1 1 1 Microtubule binding PHM7_cyt PF14703.6 EMG49534.1 - 0.17 12.1 6.6 0.19 11.9 0.1 2.6 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Ead_Ea22 PF13935.6 EMG49534.1 - 2.1 9.0 8.3 43 4.8 8.0 2.8 2 1 0 2 2 2 0 Ead/Ea22-like protein Secretin_N_2 PF07655.13 EMG49536.1 - 0.12 12.9 20.4 3.7 8.1 8.1 2.5 1 1 1 2 2 2 0 Secretin N-terminal domain Apt1 PF10351.9 EMG49536.1 - 0.23 10.3 7.7 0.28 10.0 7.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP1 PF08601.10 EMG49536.1 - 0.24 11.1 19.9 0.27 10.9 19.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Endomucin PF07010.12 EMG49536.1 - 0.61 10.0 25.5 0.89 9.5 25.5 1.2 1 0 0 1 1 1 0 Endomucin Macoilin PF09726.9 EMG49536.1 - 0.86 8.1 7.2 0.86 8.1 7.2 1.0 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 EMG49536.1 - 4.7 7.0 14.5 6.2 6.6 14.5 1.1 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 EMG49536.1 - 6.7 5.4 9.4 8.8 5.0 9.4 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 EMG49536.1 - 8.7 3.3 8.2 9.3 3.2 8.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 EMG49536.1 - 8.9 4.3 7.3 9.8 4.2 7.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIE_alpha PF02002.17 EMG49537.1 - 0.095 12.6 2.5 0.19 11.6 1.1 1.8 1 1 0 2 2 2 0 TFIIE alpha subunit ABC_membrane_2 PF06472.15 EMG49538.1 - 2.6e-65 220.5 0.0 3.5e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EMG49538.1 - 2e-19 70.5 0.0 5.3e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMG49538.1 - 0.00014 21.7 0.2 0.00045 20.1 0.0 2.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMG49538.1 - 0.0017 18.9 0.1 0.0017 18.9 0.1 2.9 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EMG49538.1 - 0.002 17.9 0.1 0.0046 16.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EMG49538.1 - 0.013 15.1 0.0 0.046 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EMG49538.1 - 0.022 14.2 0.2 0.054 12.9 0.2 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 EMG49538.1 - 0.024 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EMG49538.1 - 0.04 14.3 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EMG49538.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_15 PF13175.6 EMG49538.1 - 0.058 13.1 0.2 0.058 13.1 0.2 2.2 2 2 1 3 3 3 0 AAA ATPase domain DUF815 PF05673.13 EMG49538.1 - 0.061 12.5 0.0 0.15 11.2 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF815) ABC_membrane PF00664.23 EMG49538.1 - 0.082 12.5 0.4 0.34 10.5 0.0 2.3 2 1 1 3 3 3 0 ABC transporter transmembrane region AAA_22 PF13401.6 EMG49538.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EMG49538.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Peripla_BP_4 PF13407.6 EMG49539.1 - 0.00054 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain DUF148 PF02520.17 EMG49539.1 - 0.022 14.9 4.5 0.022 14.9 4.5 3.8 1 1 2 3 3 3 0 Domain of unknown function DUF148 Shugoshin_N PF07558.11 EMG49539.1 - 0.072 13.0 10.9 4.1 7.3 5.9 3.4 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TMF_TATA_bd PF12325.8 EMG49539.1 - 0.081 13.1 27.0 0.033 14.4 15.8 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Kri1 PF05178.12 EMG49539.1 - 0.14 12.8 5.2 0.31 11.6 0.0 3.3 2 1 0 2 2 2 0 KRI1-like family DivIC PF04977.15 EMG49539.1 - 0.47 10.3 17.6 0.18 11.6 3.4 4.0 2 1 1 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.19 EMG49539.1 - 0.7 7.7 21.1 0.67 7.8 19.7 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 EMG49539.1 - 0.83 9.8 28.8 1.9 8.7 14.6 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 EMG49539.1 - 0.93 10.2 12.9 5.3 7.7 1.3 3.9 2 1 2 4 4 4 0 SlyX DUF4472 PF14739.6 EMG49539.1 - 1.3 9.8 27.6 0.12 13.1 7.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Macoilin PF09726.9 EMG49539.1 - 1.4 7.4 30.9 2.9 6.4 30.9 1.5 1 1 0 1 1 1 0 Macoilin family TACC_C PF05010.14 EMG49539.1 - 1.7 8.4 32.6 0.028 14.2 15.5 3.2 1 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Jnk-SapK_ap_N PF09744.9 EMG49539.1 - 2.3 8.4 30.6 2.2 8.5 19.0 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Syntaxin-6_N PF09177.11 EMG49539.1 - 3.2 8.4 23.3 1.7 9.3 2.5 3.7 3 1 1 4 4 3 0 Syntaxin 6, N-terminal Fez1 PF06818.15 EMG49539.1 - 3.4 8.1 27.3 0.7 10.3 10.1 2.5 1 1 1 2 2 2 0 Fez1 TSNAXIP1_N PF15739.5 EMG49539.1 - 4.5 7.7 23.7 0.97 9.8 7.5 3.8 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus DivIVA PF05103.13 EMG49539.1 - 5 7.2 26.0 4.5 7.4 1.3 3.7 2 1 1 3 3 3 0 DivIVA protein TolA_bind_tri PF16331.5 EMG49539.1 - 6.3 6.9 11.2 6.6 6.9 3.3 2.9 2 0 0 2 2 2 0 TolA binding protein trimerisation ApoO PF09769.9 EMG49539.1 - 7.3 6.6 7.1 2.2 8.3 0.9 3.0 1 1 1 3 3 3 0 Apolipoprotein O zf-C4H2 PF10146.9 EMG49539.1 - 8.3 6.6 29.6 1.8 8.8 14.8 2.6 1 1 1 2 2 2 0 Zinc finger-containing protein Lebercilin PF15619.6 EMG49539.1 - 8.6 6.0 33.9 8.8 5.9 17.7 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 EMG49539.1 - 9.8 6.2 32.1 1.6 8.8 18.1 3.3 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DAGK_cat PF00781.24 EMG49540.1 - 1.9e-25 88.9 0.0 3e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain LRR_4 PF12799.7 EMG49541.1 - 2.5e-23 81.7 67.2 4.8e-05 23.6 3.3 10.4 6 3 2 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG49541.1 - 4.7e-19 67.9 48.1 2.1e-05 24.2 8.3 9.2 4 4 3 7 7 7 7 Leucine rich repeat LRR_6 PF13516.6 EMG49541.1 - 6.1e-10 38.4 38.7 0.033 14.2 0.0 13.8 15 0 0 15 15 15 3 Leucine Rich repeat LRR_9 PF14580.6 EMG49541.1 - 0.00015 21.3 19.0 0.49 9.9 0.1 5.4 1 1 4 6 6 6 3 Leucine-rich repeat LRR_1 PF00560.33 EMG49541.1 - 0.0031 17.8 47.7 9.8 7.2 0.0 13.3 13 3 0 13 13 13 3 Leucine Rich Repeat FNIP PF05725.12 EMG49541.1 - 0.32 11.2 0.1 0.32 11.2 0.1 8.6 8 2 1 9 9 9 0 FNIP Repeat RPN2_C PF18004.1 EMG49542.1 - 1.6e-54 184.1 8.2 2.4e-54 183.6 8.2 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EMG49542.1 - 9.5e-40 133.1 23.3 1.6e-06 28.2 0.4 8.8 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EMG49542.1 - 3.1e-18 66.0 0.9 1.3e-13 51.1 0.0 4.2 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EMG49542.1 - 2.5e-05 24.2 0.0 1.6 9.2 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 EMG49542.1 - 0.0036 17.8 0.4 7.2 7.2 0.0 4.5 5 0 0 5 5 5 1 HEAT-like repeat RasGEF PF00617.19 EMG49542.1 - 0.22 11.7 2.7 0.15 12.3 0.6 1.9 2 0 0 2 2 2 0 RasGEF domain 2-Hacid_dh_C PF02826.19 EMG49543.1 - 2.8e-55 186.4 0.1 6.3e-55 185.3 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMG49543.1 - 3.4e-39 133.6 0.1 4.6e-39 133.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMG49543.1 - 5.2e-05 23.5 1.6 8.3e-05 22.8 0.2 2.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EMG49543.1 - 0.00022 21.3 0.2 0.00062 19.9 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 EMG49543.1 - 0.0049 16.6 0.0 0.018 14.8 0.0 2.0 1 0 0 1 1 1 1 ACT domain XdhC_C PF13478.6 EMG49543.1 - 0.0087 16.6 0.0 0.068 13.7 0.0 2.4 2 1 0 2 2 2 1 XdhC Rossmann domain IlvN PF07991.12 EMG49543.1 - 0.015 14.9 0.2 0.045 13.3 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DpaA_N PF16924.5 EMG49543.1 - 0.14 12.2 0.1 5.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain Mso1_Sec1_bdg PF14475.6 EMG49544.1 - 5.8e-19 67.4 0.1 1.3e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Mso1_C PF14477.6 EMG49544.1 - 4.2e-09 36.7 5.9 4.2e-09 36.7 5.9 2.7 1 1 1 2 2 2 1 Membrane-polarising domain of Mso1 Y_phosphatase2 PF03162.13 EMG49545.1 - 6.5e-32 110.4 3.9 6.5e-32 110.4 3.9 2.8 2 2 0 2 2 2 1 Tyrosine phosphatase family PBP1_TM PF14812.6 EMG49545.1 - 2.6 8.5 6.8 2.3 8.7 3.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CoA_binding_2 PF13380.6 EMG49546.1 - 3.4e-33 114.6 0.0 4.2e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 EMG49546.1 - 0.0059 17.3 0.0 0.0093 16.6 0.0 1.4 1 1 0 1 1 1 1 CoA binding domain ATG101 PF07855.12 EMG49547.1 - 1.4e-34 119.3 0.2 1.6e-34 119.1 0.2 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Pkinase PF00069.25 EMG49548.1 - 4.2e-48 164.0 1.2 1e-47 162.7 1.2 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49548.1 - 2.8e-21 76.0 0.0 5e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 EMG49548.1 - 0.0049 17.0 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EMG49548.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans PF04082.18 EMG49549.1 - 0.00034 19.7 0.1 0.0015 17.7 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG49549.1 - 0.00043 20.3 12.4 0.00077 19.5 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.21 EMG49551.1 - 1.4e-49 168.5 0.2 1.8e-49 168.2 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NAT PF04768.13 EMG49552.1 - 7.4e-51 172.2 0.9 2.7e-50 170.3 0.1 2.1 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EMG49552.1 - 7.3e-31 107.1 0.0 1.6e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EMG49552.1 - 6.1e-28 98.0 0.0 1.2e-27 97.0 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 EMG49552.1 - 0.016 15.3 0.0 0.048 13.8 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Herpes_UL92 PF03048.14 EMG49553.1 - 0.027 14.2 0.4 0.038 13.8 0.4 1.3 1 0 0 1 1 1 0 UL92 family SCVP PF17619.2 EMG49553.1 - 0.092 13.6 0.3 0.16 12.8 0.3 1.4 1 0 0 1 1 1 0 Secreted clade V proteins DUF5449 PF17528.2 EMG49553.1 - 0.1 12.4 0.4 0.18 11.5 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5449) ApoL PF05461.11 EMG49554.1 - 0.011 15.1 0.0 0.013 14.9 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein L CAF20 PF17052.5 EMG49555.1 - 2.2e-63 213.2 3.1 2.5e-63 213.0 3.1 1.0 1 0 0 1 1 1 1 Cap associated factor Tma16 PF11176.8 EMG49556.1 - 4.8e-48 162.8 4.6 5.7e-48 162.5 4.6 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Shugoshin_N PF07558.11 EMG49556.1 - 0.047 13.6 4.2 0.14 12.0 4.2 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region LIN52 PF10044.9 EMG49557.1 - 0.13 13.0 0.8 37 5.1 0.0 4.0 3 0 0 3 3 3 0 Retinal tissue protein Tma16 PF11176.8 EMG49558.1 - 4.8e-48 162.8 4.6 5.7e-48 162.5 4.6 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Shugoshin_N PF07558.11 EMG49558.1 - 0.047 13.6 4.2 0.14 12.0 4.2 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region RGS PF00615.19 EMG49560.1 - 3.3e-09 37.1 0.6 0.00064 20.0 0.2 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF1199 PF06712.11 EMG49560.1 - 0.97 9.5 5.2 0.25 11.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) SWI2_SNF2 PF18766.1 EMG49562.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase IPPT PF01715.17 EMG49563.1 - 5.1e-65 219.5 0.2 8.2e-65 218.8 0.2 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EMG49563.1 - 0.00038 19.9 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase AAA_18 PF13238.6 EMG49563.1 - 0.0042 17.6 0.5 0.33 11.5 0.5 2.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMG49563.1 - 0.0084 16.3 0.0 0.16 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arginase PF00491.21 EMG49563.1 - 0.029 13.9 0.1 0.062 12.8 0.1 1.5 1 0 0 1 1 1 0 Arginase family RNA_helicase PF00910.22 EMG49563.1 - 0.039 14.4 0.1 0.13 12.7 0.1 2.0 1 1 0 1 1 1 0 RNA helicase BRO1 PF03097.18 EMG49564.1 - 9.7e-107 357.1 1.7 1.6e-106 356.4 1.7 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EMG49564.1 - 1.6e-67 227.9 8.4 3.1e-67 227.0 8.4 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Jnk-SapK_ap_N PF09744.9 EMG49564.1 - 2.4 8.4 12.1 1.8 8.7 1.5 2.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Myb_DNA-binding PF00249.31 EMG49565.1 - 1.2e-25 89.4 4.4 3.1e-12 46.5 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMG49565.1 - 2.4e-22 78.9 6.6 9.4e-14 51.4 1.1 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EMG49565.1 - 0.013 15.5 0.0 0.013 15.5 0.0 3.7 4 1 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 EMG49565.1 - 0.016 15.4 0.2 0.086 13.0 0.2 2.3 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 rhaM PF05336.13 EMG49565.1 - 0.023 14.7 3.6 1.4 9.0 0.8 3.4 2 1 0 2 2 2 0 L-rhamnose mutarotase KORA PF16509.5 EMG49565.1 - 0.48 10.7 3.8 1.7 9.0 0.1 3.3 4 0 0 4 4 4 0 TrfB plasmid transcriptional repressor LIP PF03583.14 EMG49566.1 - 6e-08 32.3 0.0 7.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase LRR_4 PF12799.7 EMG49567.1 - 0.002 18.5 11.7 6.1 7.4 0.6 6.2 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG49567.1 - 0.22 11.3 6.3 0.22 11.3 2.2 3.2 4 0 0 4 4 4 0 Leucine rich repeat FNIP PF05725.12 EMG49567.1 - 0.24 11.6 17.5 1.6 9.0 0.0 6.5 6 1 1 7 7 7 0 FNIP Repeat F-box-like PF12937.7 EMG49567.1 - 0.7 9.8 3.3 0.97 9.4 0.5 2.4 2 0 0 2 2 2 0 F-box-like LIP PF03583.14 EMG49568.1 - 1.5e-107 359.2 0.0 1.7e-107 359.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EMG49568.1 - 0.025 14.0 0.0 0.46 9.9 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family FNIP PF05725.12 EMG49569.1 - 0.0014 18.7 16.6 0.0058 16.8 0.5 5.1 4 1 0 4 4 4 2 FNIP Repeat LRR_4 PF12799.7 EMG49569.1 - 0.013 15.9 13.3 7.7 7.1 0.5 6.0 5 1 2 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG49569.1 - 5.1 6.9 8.8 2.8 7.8 0.2 3.9 4 1 0 4 4 4 0 Leucine rich repeat Nup188 PF10487.9 EMG49570.1 - 0 1128.6 35.7 0 1128.6 35.7 1.8 3 0 0 3 3 3 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 EMG49570.1 - 1.7e-26 93.0 3.9 4.1e-26 91.7 3.9 1.6 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Acetyltransf_14 PF03421.16 EMG49570.1 - 0.0049 16.9 0.6 3.3 7.8 0.1 2.8 2 0 0 2 2 2 2 YopJ Serine/Threonine acetyltransferase zf-H2C2 PF09337.10 EMG49570.1 - 0.32 11.3 1.0 12 6.2 0.6 2.7 2 0 0 2 2 2 0 H2C2 zinc finger Pyrophosphatase PF00719.19 EMG49571.1 - 8.1e-44 149.2 0.2 1.1e-43 148.8 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Fucose_iso_C PF02952.17 EMG49571.1 - 0.14 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain RSN1_7TM PF02714.15 EMG49572.1 - 1.1e-85 287.2 24.0 2.4e-85 286.2 24.0 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EMG49572.1 - 3.9e-38 130.7 0.3 3.9e-38 130.7 0.3 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EMG49572.1 - 8.6e-25 88.0 1.0 8.6e-25 88.0 1.0 1.9 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EMG49572.1 - 1.8e-23 82.5 0.0 4.7e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF1804 PF08822.11 EMG49572.1 - 0.042 13.8 0.4 0.079 12.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) DUF3449 PF11931.8 EMG49573.1 - 0.12 12.2 2.3 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) PPTA PF01239.22 EMG49574.1 - 9.6e-38 126.8 11.2 8e-09 35.0 1.3 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.11 EMG49574.1 - 0.015 15.2 0.4 0.044 13.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) TPR_2 PF07719.17 EMG49574.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat N2227 PF07942.12 EMG49575.1 - 1.2e-46 159.2 0.0 1.8e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Syntaxin-5_N PF11416.8 EMG49575.1 - 0.14 11.4 0.2 0.46 9.8 0.2 1.9 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain Sir1 PF11603.8 EMG49575.1 - 1.2 9.6 6.8 1.8 9.0 3.4 2.5 2 1 0 2 2 2 0 Regulatory protein Sir1 NLE PF08154.12 EMG49576.1 - 7.9e-23 80.8 0.1 1.5e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 EMG49576.1 - 4.9e-21 74.7 10.5 2.6e-05 24.9 0.2 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 EMG49576.1 - 2.1e-06 26.7 4.2 0.016 13.9 0.5 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EMG49576.1 - 0.045 13.1 1.1 7 5.9 0.1 2.4 2 1 0 2 2 2 0 WD40-like domain GMP_synt_C PF00958.22 EMG49577.1 - 3.4e-44 148.8 0.1 7.6e-44 147.7 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EMG49577.1 - 4.5e-42 144.0 0.0 7.8e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EMG49577.1 - 1.9e-09 37.0 0.1 2.9e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EMG49577.1 - 6.3e-07 29.4 0.1 6.3e-06 26.1 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.13 EMG49577.1 - 0.0011 18.5 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EMG49577.1 - 0.022 13.5 0.1 0.045 12.6 0.1 1.5 1 0 0 1 1 1 0 tRNA methyl transferase PIH1 PF08190.12 EMG49577.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 PIH1 N-terminal domain ACPS PF01648.20 EMG49578.1 - 1.9e-16 60.2 0.1 2.2e-16 60.0 0.1 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EMG49578.1 - 0.0067 16.5 0.0 0.052 13.7 0.0 2.1 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain Mtc PF03820.17 EMG49579.1 - 1.1e-122 409.0 0.1 1.2e-122 408.9 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier GHMP_kinases_N PF00288.26 EMG49580.1 - 1.4e-17 63.7 1.0 5e-17 61.9 0.1 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMG49580.1 - 2.6e-09 37.3 0.0 5.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EMG49580.1 - 0.00043 19.8 0.0 0.0016 17.9 0.0 2.0 2 0 0 2 2 2 1 Galactokinase galactose-binding signature LRR_4 PF12799.7 EMG49581.1 - 0.0004 20.7 2.1 2.3 8.7 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) FNIP PF05725.12 EMG49581.1 - 0.16 12.2 7.8 9.3 6.5 0.0 4.7 4 1 2 6 6 5 0 FNIP Repeat LIP PF03583.14 EMG49582.1 - 2.2e-104 348.8 0.0 3.1e-104 348.3 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase LRR_4 PF12799.7 EMG49582.1 - 0.015 15.7 4.3 2.6 8.6 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Peptidase_S9 PF00326.21 EMG49582.1 - 0.17 11.4 0.0 4.9 6.6 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family LRR_8 PF13855.6 EMG49582.1 - 0.66 9.8 7.9 0.52 10.1 0.5 3.5 4 0 0 4 4 4 0 Leucine rich repeat FNIP PF05725.12 EMG49582.1 - 0.82 9.9 11.9 36 4.6 0.1 5.3 5 2 0 5 5 5 0 FNIP Repeat FNIP PF05725.12 EMG49583.1 - 7.5e-06 26.0 9.3 0.091 12.9 0.1 5.5 4 1 0 4 4 4 2 FNIP Repeat C1ORF64 PF15547.6 EMG49583.1 - 0.21 12.1 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein BSP_II PF05432.11 EMG49583.1 - 0.43 10.2 7.7 0.63 9.7 7.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Osteopontin PF00865.18 EMG49583.1 - 3 7.3 33.9 4.5 6.7 33.9 1.2 1 0 0 1 1 1 0 Osteopontin LRR_8 PF13855.6 EMG49583.1 - 3.7 7.4 8.2 6.7 6.6 0.1 4.2 4 2 1 5 5 5 0 Leucine rich repeat Methyltransf_28 PF02636.17 EMG49584.1 - 1.6e-40 139.4 0.0 2.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Iso_dh PF00180.20 EMG49586.1 - 2e-82 277.2 0.1 2.5e-82 276.8 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Rep_fac-A_3 PF08661.11 EMG49587.1 - 1.2e-26 93.1 0.1 1.3e-26 93.0 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF2518 PF10726.9 EMG49587.1 - 0.015 14.9 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of function (DUF2518) Ten1_2 PF15490.6 EMG49587.1 - 0.061 13.0 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit PFU PF09070.11 EMG49588.1 - 3e-43 146.7 0.1 5.4e-43 145.8 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 EMG49588.1 - 8.7e-41 140.0 1.1 1.4e-40 139.3 1.1 1.3 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 EMG49588.1 - 1.8e-32 110.9 13.6 1.2e-05 26.0 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG49588.1 - 0.00051 20.3 0.1 0.054 13.8 0.0 4.1 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EMG49588.1 - 0.00066 19.1 0.2 0.11 11.8 0.0 3.6 1 1 1 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 EMG49588.1 - 0.0081 16.2 0.0 0.35 10.9 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Adenylsucc_synt PF00709.21 EMG49589.1 - 1e-180 601.2 0.0 1.1e-180 601.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CMAS PF02353.20 EMG49590.1 - 1.3e-64 218.2 0.3 1.6e-64 217.9 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EMG49590.1 - 3.5e-15 56.2 0.0 5.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG49590.1 - 5.7e-10 39.8 0.0 9.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG49590.1 - 4.9e-09 36.7 0.0 8.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EMG49590.1 - 0.00013 22.2 0.1 0.00032 20.9 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 EMG49590.1 - 0.00032 21.4 0.0 0.00065 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMG49590.1 - 0.00084 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EMG49590.1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 EMG49590.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EMG49590.1 - 0.051 13.1 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain COX7C PF02935.16 EMG49590.1 - 0.2 11.9 3.9 0.65 10.3 3.9 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc BING4CT PF08149.11 EMG49591.1 - 1.1e-38 130.8 0.0 2.6e-36 123.3 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EMG49591.1 - 5.7e-07 29.8 0.0 0.31 11.4 0.0 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMG49591.1 - 0.0012 19.6 4.7 0.0035 18.1 0.0 3.9 5 1 0 5 5 5 1 WD domain, G-beta repeat Malate_synthase PF01274.22 EMG49592.1 - 1.8e-228 759.1 0.0 2.1e-228 758.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 EMG49592.1 - 0.01 15.0 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Turandot PF07240.11 EMG49592.1 - 0.15 12.0 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Mito_carr PF00153.27 EMG49593.1 - 2e-44 149.5 7.2 2.9e-18 65.6 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-CCHC PF00098.23 EMG49594.1 - 8e-05 22.5 41.1 0.0033 17.4 3.2 5.5 5 1 0 5 5 5 4 Zinc knuckle zf-C2H2_10 PF16588.5 EMG49594.1 - 0.039 13.7 12.8 0.11 12.3 4.3 2.8 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_3 PF13917.6 EMG49594.1 - 1.4 8.9 29.8 1.1 9.2 6.4 5.2 2 1 2 4 4 4 0 Zinc knuckle DUF35_N PF12172.8 EMG49594.1 - 1.8 8.5 0.0 1.8 8.5 0.0 4.4 5 0 0 5 5 5 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FAD_binding_8 PF08022.12 EMG49596.1 - 0.076 13.1 0.0 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 FAD-binding domain LAGLIDADG_3 PF14528.6 EMG49596.1 - 0.12 12.7 0.4 0.72 10.2 0.0 2.5 2 1 0 2 2 2 0 LAGLIDADG-like domain SDA1 PF05285.12 EMG49596.1 - 5 6.5 9.2 6.9 6.0 9.2 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EMG49596.1 - 6.4 6.0 8.0 8.5 5.6 8.0 1.1 1 0 0 1 1 1 0 BUD22 SURF1 PF02104.15 EMG49597.1 - 8.3e-41 140.1 0.0 1.1e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 SURF1 family GET2 PF08690.10 EMG49598.1 - 6.7e-96 321.6 0.0 7.6e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 DASH_Dam1 PF08653.10 EMG49599.1 - 4e-25 87.4 1.9 1e-24 86.0 0.2 2.1 2 0 0 2 2 2 1 DASH complex subunit Dam1 Aminopep PF10023.9 EMG49599.1 - 0.0073 15.7 0.1 0.0098 15.3 0.1 1.2 1 0 0 1 1 1 1 Putative aminopeptidase TRPM_tetra PF16519.5 EMG49599.1 - 0.022 14.9 0.5 0.9 9.7 0.0 2.3 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Occludin_ELL PF07303.13 EMG49599.1 - 0.1 13.3 2.4 1.9 9.2 0.0 2.6 3 0 0 3 3 3 0 Occludin homology domain DHO_dh PF01180.21 EMG49600.1 - 1.8e-99 332.7 0.0 2.3e-99 332.4 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EMG49600.1 - 0.0094 15.0 0.1 0.99 8.4 0.3 2.7 2 1 0 2 2 2 2 FMN-dependent dehydrogenase HIM1 PF08732.10 EMG49604.1 - 4.9e-10 39.2 0.0 6.7e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.6 EMG49604.1 - 1.8e-09 37.8 0.0 2.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMG49604.1 - 1.3e-07 31.3 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EMG49604.1 - 0.0083 15.7 0.3 0.027 14.0 0.3 1.8 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EMG49604.1 - 0.026 15.0 0.1 0.11 12.9 0.1 2.1 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EMG49604.1 - 0.052 13.7 0.0 0.77 9.9 0.0 2.5 2 1 1 3 3 3 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EMG49604.1 - 0.063 12.4 0.0 3.7 6.6 0.0 2.4 1 1 0 2 2 2 0 Male sterility protein GRDP-like PF07173.12 EMG49605.1 - 1.9e-21 77.2 2.4 4e-19 69.7 0.1 2.8 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like TPR_2 PF07719.17 EMG49606.1 - 1.7e-29 99.5 31.1 5e-05 23.1 0.4 15.0 15 0 0 15 15 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 EMG49606.1 - 4.7e-27 94.3 12.4 3.5e-07 30.6 0.0 10.6 8 4 3 11 11 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 EMG49606.1 - 1e-26 91.3 11.7 0.0016 19.1 0.0 11.4 9 3 3 12 12 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 EMG49606.1 - 5.8e-26 90.9 7.8 3.6e-06 27.5 0.0 7.5 7 1 1 8 8 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 EMG49606.1 - 6.2e-26 89.1 38.1 0.00011 21.8 0.4 14.9 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_8 PF13181.6 EMG49606.1 - 4.1e-24 82.7 29.2 0.0002 21.3 0.1 14.2 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_11 PF13414.6 EMG49606.1 - 1.2e-22 79.3 17.2 0.00016 21.3 0.2 9.7 8 2 2 10 10 8 6 TPR repeat TPR_12 PF13424.6 EMG49606.1 - 2.7e-21 75.7 22.1 3.7e-05 23.9 0.0 11.5 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_9 PF13371.6 EMG49606.1 - 1.5e-13 50.7 1.1 0.0078 16.3 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EMG49606.1 - 1.7e-13 50.2 14.9 0.1 13.3 0.0 12.2 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMG49606.1 - 1.1e-12 47.4 22.9 0.043 14.2 0.2 10.2 12 0 0 12 12 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 EMG49606.1 - 3.2e-12 45.6 13.6 0.012 15.6 0.2 9.6 9 0 0 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG49606.1 - 2.5e-11 43.6 14.4 0.00025 21.2 0.0 6.9 6 1 1 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_22 PF18833.1 EMG49606.1 - 6.8e-10 39.0 0.3 2.7e-09 37.0 0.0 2.3 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_15 PF13429.6 EMG49606.1 - 1.4e-05 24.4 15.8 0.024 13.9 0.0 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat NARP1 PF12569.8 EMG49606.1 - 2.6e-05 23.4 0.4 0.053 12.4 0.0 3.9 4 0 0 4 4 4 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 EMG49606.1 - 5.8e-05 23.1 11.7 1.1 9.4 0.0 7.2 7 0 0 7 7 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 EMG49606.1 - 7.1e-05 23.1 0.0 18 6.3 0.0 4.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EMG49606.1 - 8.4e-05 22.1 0.6 1.7 7.9 0.0 4.4 5 0 0 5 5 4 1 MalT-like TPR region SHNi-TPR PF10516.9 EMG49606.1 - 0.00031 20.1 2.9 5.5 6.5 0.1 4.9 5 0 0 5 5 5 1 SHNi-TPR TPR_10 PF13374.6 EMG49606.1 - 0.00046 20.0 21.9 0.49 10.3 0.3 7.6 9 0 0 9 9 6 2 Tetratricopeptide repeat RPN7 PF10602.9 EMG49606.1 - 0.0051 16.5 5.7 0.32 10.7 0.1 4.7 5 0 0 5 5 4 1 26S proteasome subunit RPN7 Alkyl_sulf_dimr PF14863.6 EMG49606.1 - 0.011 16.2 2.2 81 3.7 0.0 5.5 7 1 0 7 7 4 0 Alkyl sulfatase dimerisation HrpB1_HrpK PF09613.10 EMG49606.1 - 0.021 14.4 0.0 0.12 12.0 0.0 2.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF3856 PF12968.7 EMG49606.1 - 0.043 13.9 1.7 9 6.4 0.0 3.6 4 0 0 4 4 2 0 Domain of Unknown Function (DUF3856) DUF5588 PF17826.1 EMG49606.1 - 0.11 11.4 3.6 0.56 9.0 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5588) PaREP1 PF05942.11 EMG49606.1 - 0.15 12.0 1.3 1.5 8.8 0.1 3.0 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family PPTA PF01239.22 EMG49606.1 - 0.15 11.9 0.5 1 9.2 0.1 2.8 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Sel1 PF08238.12 EMG49606.1 - 0.76 10.5 5.4 60 4.5 0.0 4.8 5 0 0 5 5 3 0 Sel1 repeat TPR_20 PF14561.6 EMG49606.1 - 0.79 10.1 11.8 16 5.9 0.0 6.2 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 EMG49606.1 - 2.5 8.2 6.1 2.5 8.2 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat MMR_HSR1_C PF08438.10 EMG49607.1 - 3.7e-36 124.1 0.0 5.7e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EMG49607.1 - 5.9e-19 68.2 0.0 1.2e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMG49607.1 - 3.5e-08 33.1 0.1 7.8e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EMG49607.1 - 0.005 16.4 0.0 0.52 9.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EMG49607.1 - 0.018 14.0 0.3 0.052 12.5 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EMG49607.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 EMG49607.1 - 0.082 12.7 0.2 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EMG49607.1 - 0.23 11.4 0.4 8.7 6.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Cg6151-P PF10233.9 EMG49608.1 - 1.1e-37 128.8 16.2 1.4e-37 128.5 16.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF5592 PF17332.2 EMG49608.1 - 0.036 14.6 2.2 0.036 14.6 2.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5592) DUF4516 PF14990.6 EMG49608.1 - 0.21 11.3 1.3 0.62 9.8 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) MFS_2 PF13347.6 EMG49608.1 - 0.61 8.6 11.5 0.7 8.4 2.7 2.0 1 1 0 2 2 2 0 MFS/sugar transport protein Ribosomal_L44 PF00935.19 EMG49610.1 - 4.8e-35 119.9 15.0 7.5e-35 119.3 15.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Mannosyl_trans3 PF11051.8 EMG49611.1 - 9.3e-83 277.7 0.0 1.6e-82 277.0 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Aim21 PF11489.8 EMG49612.1 - 2.7e-07 29.9 27.4 2.7e-07 29.9 27.4 5.0 2 1 3 5 5 5 2 Altered inheritance of mitochondria protein 21 NTF2 PF02136.20 EMG49613.1 - 3.5e-33 114.7 0.1 6.6e-33 113.8 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain TFA2_Winged_2 PF18121.1 EMG49613.1 - 3.3e-21 74.7 0.1 1.1e-20 73.1 0.1 2.0 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EMG49613.1 - 7.4e-18 64.6 1.0 2.3e-17 63.0 1.0 1.9 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF4518 PF15008.6 EMG49613.1 - 0.069 12.3 1.5 0.12 11.5 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4518) F-box-like PF12937.7 EMG49614.1 - 0.00064 19.6 0.0 0.0018 18.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like Gti1_Pac2 PF09729.9 EMG49615.1 - 7.4e-55 185.8 0.2 7.4e-55 185.8 0.2 3.0 2 1 0 2 2 2 1 Gti1/Pac2 family ERO1 PF04137.15 EMG49616.1 - 4e-116 388.1 1.0 4e-116 388.1 1.0 1.4 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DEAD PF00270.29 EMG49618.1 - 3.4e-50 170.2 0.0 8.6e-50 168.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG49618.1 - 4.8e-34 117.0 1.0 7.2e-31 106.8 0.2 3.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG49618.1 - 4.5e-08 33.3 0.0 4.5e-08 33.3 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EMG49618.1 - 0.00015 21.1 0.2 0.00015 21.1 0.2 2.8 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 EMG49618.1 - 0.0051 15.7 0.5 0.0051 15.7 0.5 3.4 3 1 1 4 4 4 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 EMG49618.1 - 0.0072 15.7 0.1 0.0072 15.7 0.1 3.0 3 1 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit DUF3807 PF12720.7 EMG49618.1 - 1.9 8.7 16.4 3.4 7.9 16.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF4718 PF15842.5 EMG49618.1 - 3 7.6 7.9 5 6.9 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF4637 PF15470.6 EMG49618.1 - 5.1 6.8 9.2 9 6.0 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Tim54 PF11711.8 EMG49618.1 - 6.2 5.5 14.6 10 4.8 14.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GATA PF00320.27 EMG49619.1 - 1.4e-29 101.3 23.0 5.8e-16 57.8 6.0 3.1 3 0 0 3 3 3 2 GATA zinc finger ArfGap PF01412.18 EMG49619.1 - 4.2e-05 23.6 7.4 0.043 13.9 0.2 3.0 3 0 0 3 3 3 2 Putative GTPase activating protein for Arf TDP43_N PF18694.1 EMG49619.1 - 0.0036 17.1 0.0 0.81 9.6 0.0 2.4 2 0 0 2 2 2 1 Transactive response DNA-binding protein N-terminal domain TF_Zn_Ribbon PF08271.12 EMG49619.1 - 0.0046 16.4 0.4 0.0046 16.4 0.4 3.0 3 0 0 3 3 2 2 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 EMG49619.1 - 0.013 15.4 0.5 0.013 15.4 0.5 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 EMG49619.1 - 0.14 12.1 3.9 4.3 7.2 0.5 2.8 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.10 EMG49619.1 - 0.17 12.0 13.8 0.32 11.2 0.1 3.5 4 0 0 4 4 4 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 EMG49619.1 - 0.2 11.8 11.9 0.3 11.3 0.6 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF4684 PF15736.5 EMG49619.1 - 1 8.0 6.2 1.6 7.3 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) zf-RRN7 PF11781.8 EMG49619.1 - 1.3 8.8 16.2 0.29 10.9 0.5 3.2 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 EMG49619.1 - 4.2 7.5 19.2 0.46 10.5 0.2 3.9 3 1 1 4 4 4 0 Double zinc ribbon Pkinase PF00069.25 EMG49620.1 - 4e-43 147.7 1.5 1.1e-41 142.9 0.0 3.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49620.1 - 5.1e-25 88.2 0.0 1.6e-24 86.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5408 PF17402.2 EMG49621.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5408) DSPc PF00782.20 EMG49622.1 - 3.6e-31 107.7 0.3 3.6e-31 107.7 0.3 2.3 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMG49622.1 - 0.00028 20.5 0.3 0.00087 18.9 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EMG49622.1 - 0.0052 17.1 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 Rit1 DUSP-like domain MecA PF05389.12 EMG49622.1 - 1.3 8.6 7.7 0.56 9.8 1.4 2.5 2 1 0 2 2 2 0 Negative regulator of genetic competence (MecA) Syja_N PF02383.18 EMG49623.1 - 1.7e-68 231.3 3.1 2e-68 231.1 3.1 1.0 1 0 0 1 1 1 1 SacI homology domain DUF1257 PF06868.11 EMG49623.1 - 0.084 13.1 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) Cut8 PF08559.10 EMG49624.1 - 8.1e-81 271.2 10.4 1.1e-80 270.8 10.4 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Phage_holin_6_1 PF09682.10 EMG49624.1 - 0.075 13.5 0.2 0.16 12.4 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) VPS28 PF03997.12 EMG49624.1 - 0.5 10.0 7.1 0.6 9.7 0.2 3.0 2 1 1 3 3 3 0 VPS28 protein Hydrolase_4 PF12146.8 EMG49625.1 - 1.9e-32 112.4 0.0 2.4e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMG49625.1 - 8e-16 58.5 0.0 1.1e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMG49625.1 - 1.6e-08 35.4 0.0 1.8e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EMG49625.1 - 0.0033 17.2 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EMG49625.1 - 0.039 13.5 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF915 PF06028.11 EMG49625.1 - 0.11 11.8 0.7 0.25 10.6 0.2 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) 2-Hacid_dh PF00389.30 EMG49626.1 - 6.1e-15 55.1 0.0 7.2e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF2408 PF10303.9 EMG49627.1 - 6.7e-45 153.0 34.7 1.7e-33 116.0 10.1 5.3 3 2 0 4 4 4 3 Protein of unknown function (DUF2408) PAH PF02671.21 EMG49627.1 - 3 8.1 5.8 10 6.4 0.1 3.6 3 1 1 4 4 4 0 Paired amphipathic helix repeat 2-Hacid_dh_C PF02826.19 EMG49628.1 - 8.1e-36 123.0 0.0 3.7e-35 120.9 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EMG49628.1 - 0.00048 20.3 0.0 0.00083 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EMG49628.1 - 0.0066 16.5 0.1 0.021 14.9 0.1 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TFIIE_alpha PF02002.17 EMG49629.1 - 2.5e-23 81.9 2.7 2.6e-22 78.7 0.2 2.4 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 EMG49629.1 - 0.00098 18.6 2.2 0.0077 15.7 2.1 2.4 1 1 0 1 1 1 1 TFIIB zinc-binding NodS PF05401.11 EMG49629.1 - 0.038 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) zf_UBZ PF18439.1 EMG49629.1 - 0.047 13.3 0.9 0.38 10.4 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Selenoprotein_S PF06936.11 EMG49629.1 - 0.085 12.7 6.6 1.3 8.8 2.0 2.3 2 0 0 2 2 2 0 Selenoprotein S (SelS) zf-CCHC_2 PF13696.6 EMG49629.1 - 0.33 10.8 3.9 0.24 11.3 1.0 2.1 2 0 0 2 2 2 0 Zinc knuckle SRP9-21 PF05486.12 EMG49629.1 - 0.93 9.9 4.1 0.34 11.3 1.0 1.9 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Forkhead PF00250.18 EMG49630.1 - 7.1e-34 115.9 0.2 3.3e-33 113.8 0.0 2.2 2 0 0 2 2 2 1 Forkhead domain PBP1_TM PF14812.6 EMG49630.1 - 0.46 10.9 8.9 0.32 11.4 1.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Complex1_LYR_2 PF13233.6 EMG49631.1 - 5.8e-18 65.4 3.1 1.3e-17 64.3 3.1 1.6 1 1 0 1 1 1 1 Complex1_LYR-like DDE_1 PF03184.19 EMG49632.1 - 1.5e-32 112.6 4.1 1.8e-32 112.4 1.1 2.5 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EMG49632.1 - 1.6e-14 53.7 0.3 4e-14 52.4 0.3 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 EMG49632.1 - 3.1e-05 23.6 0.0 0.0001 21.9 0.0 1.9 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain Pet100 PF09803.9 EMG49633.1 - 7.4e-10 39.2 0.0 1.2e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 Pet100 Birna_VP3 PF01767.16 EMG49633.1 - 0.027 14.6 0.6 0.033 14.3 0.6 1.1 1 0 0 1 1 1 0 Birnavirus VP3 protein ATPase_gene1 PF09527.10 EMG49633.1 - 0.046 13.9 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter HTH_25 PF13413.6 EMG49633.1 - 0.14 12.1 3.2 0.12 12.2 1.8 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Cwf_Cwc_15 PF04889.12 EMG49633.1 - 0.31 10.8 4.4 0.4 10.4 4.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF846 PF05832.12 EMG49634.1 - 1.1e-53 181.1 11.0 1.3e-53 180.8 11.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) MFS_1 PF07690.16 EMG49634.1 - 2.9 6.7 15.2 6.6 5.5 14.8 1.6 1 1 1 2 2 2 0 Major Facilitator Superfamily Anophelin PF10731.9 EMG49635.1 - 0.45 10.4 2.7 14 5.6 0.9 2.5 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Clathrin PF00637.20 EMG49636.1 - 5.8e-27 94.3 9.4 1.1e-26 93.5 2.3 3.1 3 0 0 3 3 3 2 Region in Clathrin and VPS WD40 PF00400.32 EMG49636.1 - 0.005 17.6 0.1 0.049 14.5 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat Vps39_1 PF10366.9 EMG49636.1 - 0.033 14.5 8.4 0.04 14.2 0.7 3.0 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 NAD_binding_10 PF13460.6 EMG49637.1 - 9.7e-11 41.9 0.1 1.4e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 EMG49637.1 - 1.6e-08 34.3 0.0 2.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 HIM1 Epimerase PF01370.21 EMG49637.1 - 1.4e-05 24.7 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EMG49637.1 - 0.00085 19.8 0.3 0.18 12.3 0.0 2.7 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 EMG49637.1 - 0.0054 16.3 0.2 0.014 15.0 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EMG49637.1 - 0.0067 15.6 0.0 0.29 10.2 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain DapB_N PF01113.20 EMG49637.1 - 0.013 15.6 0.0 0.11 12.6 0.0 2.3 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus LRR_8 PF13855.6 EMG49638.1 - 1.3e-07 31.3 21.6 0.0024 17.6 0.1 7.9 6 2 3 9 9 9 4 Leucine rich repeat LRR_6 PF13516.6 EMG49638.1 - 1.9e-07 30.6 14.1 1.4 9.2 0.0 8.6 6 1 2 8 8 8 3 Leucine Rich repeat LRR_9 PF14580.6 EMG49638.1 - 0.00087 18.8 0.6 0.00087 18.8 0.6 3.0 2 1 1 3 3 3 1 Leucine-rich repeat LRR_4 PF12799.7 EMG49638.1 - 0.0011 19.3 1.2 0.0011 19.3 1.2 10.8 8 4 3 11 11 11 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EMG49638.1 - 0.15 12.7 33.7 20 6.2 0.1 10.9 12 1 0 12 12 12 0 Leucine Rich Repeat dsDNA_bind PF01984.20 EMG49640.1 - 3.5 7.9 10.2 0.4 11.0 0.1 3.3 3 0 0 3 3 3 0 Double-stranded DNA-binding domain Pkinase PF00069.25 EMG49642.1 - 1.9e-69 234.0 0.7 2.9e-69 233.4 0.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49642.1 - 6.7e-52 176.3 0.2 9.6e-52 175.8 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EMG49642.1 - 3e-22 78.7 2.6 5.3e-22 77.9 0.2 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.29 EMG49642.1 - 2.9e-07 30.9 0.3 8.2e-07 29.5 0.3 1.8 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 EMG49642.1 - 4.4e-07 29.2 0.0 9e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EMG49642.1 - 7.8e-07 28.7 0.0 7.8e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EMG49642.1 - 3.1e-06 26.2 0.2 8e-06 24.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EMG49642.1 - 0.0017 17.5 0.1 0.0032 16.6 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EMG49642.1 - 0.037 13.9 0.1 0.1 12.5 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family LepB_GAP_C PF18227.1 EMG49642.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 LepB GAP domain C-terminal subdomain MFS_1 PF07690.16 EMG49643.1 - 4.8e-31 108.0 13.8 4.8e-31 108.0 13.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1218 PF06749.12 EMG49643.1 - 8.6 7.0 10.4 6.5 7.3 0.4 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) FoP_duplication PF13865.6 EMG49644.1 - 3.1e-18 66.1 7.1 3.1e-18 66.1 7.1 2.2 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 EMG49644.1 - 0.0041 16.9 0.1 0.0074 16.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EMG49644.1 - 0.0052 16.8 0.4 0.07 13.2 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Ivy PF08816.11 EMG49644.1 - 0.034 14.3 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) Pkinase PF00069.25 EMG49645.1 - 7.7e-71 238.5 0.0 1e-70 238.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49645.1 - 5.2e-39 134.1 0.0 7.1e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG49645.1 - 9.1e-06 25.2 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_5 PF15405.6 EMG49645.1 - 0.039 14.0 1.0 0.063 13.4 1.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.25 EMG49646.1 - 1.4e-28 100.0 4.2 4.1e-28 98.5 4.2 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49646.1 - 1.4e-13 50.8 0.1 2.1e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EMG49646.1 - 0.12 11.7 0.4 0.22 10.8 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_polI_A34 PF08208.11 EMG49647.1 - 4.7e-39 134.6 14.8 7.1e-39 134.0 14.8 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.12 EMG49647.1 - 0.14 12.4 5.9 0.18 12.1 5.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PTPRCAP PF15713.5 EMG49647.1 - 1.7 9.0 10.4 3.3 8.0 10.4 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RraA-like PF03737.15 EMG49648.1 - 1.6e-31 109.5 0.0 2.4e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Aldolase/RraA Glyco_hydro_31 PF01055.26 EMG49651.1 - 3.7e-142 474.6 5.9 4.7e-142 474.3 5.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EMG49651.1 - 1.5e-29 102.6 0.2 4.3e-29 101.1 0.2 1.8 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EMG49651.1 - 0.0029 17.9 0.1 0.016 15.5 0.1 2.4 1 0 0 1 1 1 1 Galactose mutarotase-like Mannosyl_trans3 PF11051.8 EMG49652.1 - 6.3e-84 281.6 1.2 6.3e-84 281.6 1.2 1.9 2 0 0 2 2 2 1 Mannosyltransferase putative AAA_14 PF13173.6 EMG49652.1 - 0.12 12.4 2.2 0.63 10.1 2.2 2.3 1 0 0 1 1 1 0 AAA domain Bul1_C PF04426.12 EMG49655.1 - 3.1e-12 46.5 2.4 5.5e-06 26.0 0.0 2.3 1 1 1 2 2 2 2 Bul1 C terminus Phage_holin_3_6 PF07332.11 EMG49656.1 - 0.11 12.6 1.6 0.16 12.1 1.6 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4519 PF15012.6 EMG49658.1 - 0.017 15.3 0.2 11 6.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF3267 PF11667.8 EMG49658.1 - 0.029 14.7 1.2 0.029 14.7 1.2 2.7 2 1 0 2 2 2 0 Putative zincin peptidase DUF2838 PF10998.8 EMG49659.1 - 3e-37 127.2 12.1 3e-37 127.2 12.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) DASH_Spc19 PF08287.11 EMG49659.1 - 0.027 14.4 1.1 0.027 14.4 1.1 1.7 2 0 0 2 2 2 0 Spc19 DUF3023 PF11224.8 EMG49659.1 - 0.047 13.5 0.9 7.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3023) HALZ PF02183.18 EMG49659.1 - 0.095 12.9 2.9 0.24 11.7 2.9 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 EMG49659.1 - 0.15 11.8 0.0 0.15 11.8 0.0 2.3 3 0 0 3 3 3 0 Septum formation initiator ZapB PF06005.12 EMG49659.1 - 1.9 9.0 7.1 0.45 11.0 3.3 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Cnn_1N PF07989.11 EMG49659.1 - 7.8 6.7 13.5 4.5 7.5 0.6 2.7 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF2070 PF09843.9 EMG49659.1 - 9.1 4.4 13.1 16 3.6 13.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DnaJ-X PF14308.6 EMG49660.1 - 2.1e-82 275.6 23.2 6.3e-49 166.3 12.5 3.5 1 1 2 3 3 3 2 X-domain of DnaJ-containing DnaJ PF00226.31 EMG49660.1 - 1.4e-18 66.8 2.3 1.4e-18 66.8 2.3 2.6 2 0 0 2 2 2 1 DnaJ domain Ribosomal_S5 PF00333.20 EMG49660.1 - 6.9e-18 64.4 0.2 6.9e-18 64.4 0.2 2.6 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EMG49660.1 - 8.2e-11 41.2 0.4 1.1e-09 37.6 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ocular_alb PF02101.15 EMG49660.1 - 0.34 9.8 0.5 0.55 9.1 0.5 1.3 1 0 0 1 1 1 0 Ocular albinism type 1 protein Peptidase_M1 PF01433.20 EMG49661.1 - 1.1e-41 142.8 2.5 1.6e-41 142.3 2.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EMG49661.1 - 1.7e-32 111.8 0.0 4.3e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EMG49661.1 - 3.6e-23 82.7 0.1 5.8e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 EMG49661.1 - 0.28 11.6 2.7 4.5 7.7 2.7 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DOPA_dioxygen PF08883.11 EMG49662.1 - 1.1e-32 112.3 0.0 1.4e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family BAG PF02179.16 EMG49663.1 - 1.6e-22 79.7 1.7 1.6e-22 79.7 1.7 1.8 2 0 0 2 2 2 1 BAG domain PDE4_UCR PF18100.1 EMG49663.1 - 0.014 16.0 0.0 0.027 15.1 0.0 1.5 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) Trimer_CC PF08954.11 EMG49663.1 - 0.095 12.3 0.3 0.21 11.2 0.3 1.6 1 0 0 1 1 1 0 Trimerisation motif PIG-L PF02585.17 EMG49664.1 - 1.4e-26 93.7 0.0 1.6e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_hydro_81 PF03639.13 EMG49664.1 - 0.02 14.1 0.1 0.025 13.7 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 N-terminal domain DUF3892 PF13031.6 EMG49664.1 - 0.16 12.6 0.9 0.57 10.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3892) Gram_pos_anchor PF00746.21 EMG49665.1 - 0.22 11.5 1.1 0.8 9.7 1.1 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Alk_phosphatase PF00245.20 EMG49667.1 - 5.1e-84 282.6 0.0 6.1e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EMG49667.1 - 0.0034 16.8 0.2 0.0069 15.8 0.2 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EMG49667.1 - 0.031 13.7 0.9 4.8 6.5 0.8 3.0 1 1 1 2 2 2 0 Sulfatase fn3 PF00041.21 EMG49668.1 - 0.0007 19.9 0.1 0.0051 17.1 0.1 2.5 1 1 0 1 1 1 1 Fibronectin type III domain fn3_2 PF16893.5 EMG49668.1 - 0.0024 18.0 0.0 0.009 16.1 0.0 2.1 1 0 0 1 1 1 1 Fibronectin type III domain Filament PF00038.21 EMG49668.1 - 0.012 15.2 31.2 0.026 14.1 19.5 2.8 1 1 1 2 2 2 0 Intermediate filament protein fn3_4 PF16794.5 EMG49668.1 - 0.038 13.9 0.0 0.34 10.9 0.0 2.4 1 1 0 1 1 1 0 Fibronectin-III type domain Spc7 PF08317.11 EMG49668.1 - 3.1 6.6 35.1 0.14 11.0 20.0 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 EMG49668.1 - 3.9 6.9 35.9 0.14 11.6 15.9 3.0 2 1 1 3 3 3 0 Golgin subfamily A member 5 PEARLI-4 PF05278.12 EMG49668.1 - 7.4 6.1 25.7 0.16 11.5 7.6 2.9 2 1 1 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) Cep57_CLD_2 PF14197.6 EMG49668.1 - 9 6.5 16.8 3.1 7.9 0.6 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Beta_elim_lyase PF01212.21 EMG49669.1 - 1.4e-80 270.7 0.0 1.6e-80 270.5 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EMG49669.1 - 7.1e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMG49669.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Actin PF00022.19 EMG49670.1 - 2.2e-66 224.2 0.0 2.8e-65 220.5 0.0 1.9 1 1 0 1 1 1 1 Actin Synuclein PF01387.17 EMG49670.1 - 0.17 12.1 0.0 0.98 9.6 0.0 2.0 2 0 0 2 2 2 0 Synuclein LDB19 PF13002.7 EMG49671.1 - 3.7e-63 212.7 0.7 6.4e-63 212.0 0.7 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 EMG49671.1 - 1.4e-06 28.5 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EMG49671.1 - 1.7e-06 28.5 3.2 0.003 18.0 0.1 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain PTS_2-RNA PF01885.16 EMG49671.1 - 0.053 13.6 0.1 0.53 10.3 0.2 2.1 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family zf-BED PF02892.15 EMG49672.1 - 9.6e-05 22.3 1.5 0.00015 21.7 0.1 2.1 2 0 0 2 2 2 1 BED zinc finger TFIIA PF03153.13 EMG49672.1 - 0.00036 20.6 3.8 0.00063 19.9 3.8 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Soyouz_module PF14313.6 EMG49672.1 - 0.095 12.5 0.3 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) DASH_Spc19 PF08287.11 EMG49672.1 - 1.4 8.8 6.6 0.062 13.2 0.8 1.6 2 0 0 2 2 2 0 Spc19 Hamartin PF04388.12 EMG49673.1 - 0.28 9.8 26.3 0.35 9.5 26.3 1.2 1 0 0 1 1 1 0 Hamartin protein Ribosomal_L44 PF00935.19 EMG49674.1 - 7.6e-36 122.4 11.2 1.1e-35 121.9 11.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L44 PF00935.19 EMG49675.1 - 2e-34 117.9 12.8 2.9e-34 117.4 12.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Pkinase PF00069.25 EMG49676.1 - 2.5e-62 210.6 7.2 3.9e-43 147.7 0.1 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49676.1 - 1.1e-28 100.3 0.2 7.4e-22 77.9 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EMG49676.1 - 6.6e-06 25.3 0.6 6.6e-06 25.3 0.6 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EMG49676.1 - 0.00077 18.9 0.0 0.00077 18.9 0.0 2.3 3 1 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMG49676.1 - 0.015 14.7 0.0 0.015 14.7 0.0 2.7 3 0 0 3 3 3 0 Kinase-like PA28_alpha PF02251.18 EMG49676.1 - 0.029 14.4 0.1 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit APH PF01636.23 EMG49676.1 - 0.03 14.2 8.8 0.11 12.4 0.3 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EMG49676.1 - 0.039 13.0 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EMG49676.1 - 0.12 11.1 0.1 0.12 11.1 0.1 2.3 3 0 0 3 3 3 0 Fungal protein kinase BNR_2 PF13088.6 EMG49676.1 - 0.15 11.4 4.9 0.13 11.6 3.3 1.6 2 0 0 2 2 2 0 BNR repeat-like domain Ytp1 PF10355.9 EMG49677.1 - 1.9e-107 358.6 9.5 1.9e-107 358.6 9.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EMG49677.1 - 7.6e-27 93.2 7.8 7.6e-27 93.2 7.8 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Bul1_C PF04426.12 EMG49678.1 - 1.2e-12 47.9 3.8 1.7e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 Bul1 C terminus Nop52 PF05997.12 EMG49678.1 - 0.031 14.1 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Bul1_N PF04425.12 EMG49680.1 - 8e-14 51.2 14.6 0.00011 21.1 2.5 3.1 1 1 2 3 3 3 3 Bul1 N terminus Arrestin_N PF00339.29 EMG49680.1 - 0.013 15.5 0.3 0.51 10.4 0.2 2.2 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Sdh5 PF03937.16 EMG49683.1 - 2e-26 91.7 1.6 3e-26 91.2 1.6 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase TAtT PF16811.5 EMG49683.1 - 0.036 13.4 0.1 0.046 13.0 0.1 1.1 1 0 0 1 1 1 0 TRAP transporter T-component EndoU_bacteria PF14436.6 EMG49683.1 - 0.071 13.5 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial EndoU nuclease EF-hand_7 PF13499.6 EMG49684.1 - 5.1e-15 55.7 4.3 1.4e-07 31.8 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EMG49684.1 - 5.4e-13 47.7 4.0 3.2e-05 23.5 0.1 5.6 6 0 0 6 6 6 3 EF-hand domain EF-hand_1 PF00036.32 EMG49684.1 - 9.6e-12 43.6 4.6 2.3e-05 23.6 0.1 5.5 6 1 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 EMG49684.1 - 7.6e-09 35.3 1.7 3.7e-06 26.7 0.1 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EMG49684.1 - 0.0017 17.8 4.2 3.4 7.3 0.1 4.8 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.6 EMG49684.1 - 0.0053 17.1 0.6 0.6 10.5 0.1 3.2 2 1 1 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 EMG49684.1 - 0.034 14.1 0.8 0.49 10.4 0.2 2.8 1 1 3 4 4 4 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EMG49684.1 - 0.037 14.4 0.1 8 6.8 0.0 2.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region S_100 PF01023.19 EMG49684.1 - 0.2 11.4 4.4 1.7 8.4 0.1 3.0 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain SUIM_assoc PF16619.5 EMG49684.1 - 0.43 10.7 2.0 0.95 9.6 1.8 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 EMG49685.1 - 2.1e-11 44.3 0.3 1.7e-06 28.5 0.4 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EMG49685.1 - 9.1e-08 32.2 0.0 0.0017 18.7 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EMG49685.1 - 5.5e-07 29.7 0.0 0.00071 19.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMG49685.1 - 1.1e-06 28.5 0.7 0.0062 17.0 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EMG49685.1 - 1.1e-06 29.0 0.1 0.00098 19.7 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.13 EMG49685.1 - 0.0036 17.1 0.1 0.016 15.1 0.1 2.2 1 0 0 1 1 1 1 KilA-N domain SF3A2 PF16835.5 EMG49686.1 - 6.9e-27 93.7 5.0 1.8e-26 92.3 5.0 1.7 1 1 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EMG49686.1 - 4.9e-07 29.9 0.8 1.4e-06 28.5 0.7 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type TLP-20 PF06088.11 EMG49686.1 - 0.005 16.7 2.0 0.0073 16.2 1.8 1.5 1 1 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PAPS_reduct PF01507.19 EMG49687.1 - 1.1e-26 94.0 0.0 1.2e-23 84.0 0.0 2.6 2 1 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HLH PF00010.26 EMG49688.1 - 1e-15 57.4 0.0 2.4e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRP14 PF15459.6 EMG49688.1 - 0.043 14.4 1.1 0.1 13.2 0.1 2.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 UPF0061 PF02696.14 EMG49690.1 - 2.6e-120 402.4 0.0 3.3e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Sec23_trunk PF04811.15 EMG49691.1 - 1.5e-62 211.3 0.0 2.3e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EMG49691.1 - 1.8e-22 79.1 0.0 4.8e-22 77.7 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EMG49691.1 - 3.2e-17 63.1 0.0 6.8e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EMG49691.1 - 1.3e-15 57.2 4.0 2.8e-15 56.1 4.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EMG49691.1 - 4e-05 23.4 0.0 0.00012 21.9 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat COG5 PF10392.9 EMG49692.1 - 1e-36 126.0 8.6 1.3e-36 125.6 1.1 3.3 2 1 0 2 2 2 2 Golgi transport complex subunit 5 DUF2011 PF09428.10 EMG49692.1 - 1.4e-17 63.7 0.2 3.3e-17 62.5 0.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Ank_2 PF12796.7 EMG49693.1 - 2e-25 89.2 0.9 8.4e-16 58.3 0.3 3.2 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMG49693.1 - 1.6e-22 79.3 0.8 6.1e-06 26.4 0.1 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMG49693.1 - 4.4e-21 75.0 0.2 1.4e-06 28.8 0.0 5.3 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMG49693.1 - 1.5e-17 61.9 0.3 2.6e-06 27.3 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EMG49693.1 - 2.5e-15 56.1 5.0 1.2e-07 31.8 0.1 5.4 6 0 0 6 6 6 3 Ankyrin repeat Bromo_TP PF07524.13 EMG49693.1 - 0.088 12.8 0.1 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Bromodomain associated OCD_Mu_crystall PF02423.15 EMG49694.1 - 3.9e-26 91.7 0.0 5e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EMG49694.1 - 6.1e-07 29.6 0.0 2.4e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GIT_CC PF16559.5 EMG49694.1 - 0.025 14.5 0.0 0.072 13.0 0.0 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor RPAP3_C PF13877.6 EMG49695.1 - 0.057 14.0 0.4 0.29 11.7 0.1 2.3 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 Lectin_C PF00059.21 EMG49695.1 - 0.74 10.6 2.4 0.89 10.3 0.6 2.2 2 1 0 2 2 2 0 Lectin C-type domain DUF1765 PF08578.10 EMG49695.1 - 1.5 9.3 9.0 4 7.9 5.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1765) Mito_carr PF00153.27 EMG49696.1 - 3.3e-51 171.2 0.8 1.8e-16 59.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Raffinose_syn PF05691.12 EMG49696.1 - 0.15 9.8 0.0 0.18 9.6 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 SH3_1 PF00018.28 EMG49697.1 - 5.5e-12 45.1 0.2 1e-11 44.3 0.2 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 EMG49697.1 - 7.8e-12 45.4 3.8 1.1e-11 44.8 3.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.17 EMG49697.1 - 1.4e-09 37.5 0.0 2.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EMG49697.1 - 2e-09 37.2 0.1 3.4e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 EMG49697.1 - 0.0033 17.0 6.9 0.0063 16.1 6.9 1.4 1 0 0 1 1 1 1 Vps5 C terminal like BAR_3 PF16746.5 EMG49697.1 - 0.01 15.5 11.4 0.016 14.9 11.4 1.2 1 0 0 1 1 1 0 BAR domain of APPL family TTRAP PF14203.6 EMG49697.1 - 0.051 13.6 1.1 0.16 12.0 0.1 2.4 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein Osmo_CC PF08946.10 EMG49697.1 - 0.069 13.4 0.7 0.93 9.8 0.1 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DEAD PF00270.29 EMG49698.1 - 1.9e-34 119.0 0.1 1.2e-33 116.4 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG49698.1 - 8.4e-24 84.1 0.6 2.4e-22 79.4 0.0 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Pept_tRNA_hydro PF01195.19 EMG49698.1 - 2.2e-19 70.1 0.0 5.9e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase ResIII PF04851.15 EMG49698.1 - 6.7e-09 36.0 0.8 2.3e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EMG49698.1 - 0.0025 17.2 0.0 0.0057 16.0 0.0 1.6 1 0 0 1 1 1 1 SecA DEAD-like domain SWI2_SNF2 PF18766.1 EMG49698.1 - 0.039 13.6 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Glyco_hydro_47 PF01532.20 EMG49698.1 - 0.057 12.3 0.7 0.12 11.2 0.7 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 Phenol_Hydrox PF02332.18 EMG49698.1 - 0.059 12.9 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase PhoH PF02562.16 EMG49698.1 - 0.076 12.5 0.2 1.8 8.0 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein Sad1_UNC PF07738.13 EMG49699.1 - 1.1e-34 119.3 1.3 1.5e-34 118.9 0.1 1.9 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal KRAP_IP3R_bind PF14722.6 EMG49699.1 - 0.00025 20.8 3.8 0.004 16.9 0.0 2.6 2 1 0 2 2 2 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain F5_F8_type_C PF00754.25 EMG49699.1 - 0.00055 20.0 0.1 0.0036 17.4 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain DUF3490 PF11995.8 EMG49699.1 - 0.051 13.4 0.8 0.097 12.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) FBA_2 PF07735.17 EMG49699.1 - 0.063 13.4 0.2 0.063 13.4 0.2 2.8 3 0 0 3 3 3 0 F-box associated FidL_like PF15941.5 EMG49699.1 - 0.56 10.7 4.7 0.34 11.4 1.3 2.4 2 0 0 2 2 2 0 FidL-like putative membrane protein MFS_1 PF07690.16 EMG49700.1 - 7.3e-32 110.6 26.3 7.3e-32 110.6 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG49700.1 - 1.7e-11 43.7 22.5 2.5e-11 43.1 22.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Alk_phosphatase PF00245.20 EMG49701.1 - 6.5e-114 381.1 0.0 7.8e-114 380.8 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EMG49701.1 - 1.2e-05 24.8 0.1 4.8e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily MASE3 PF17159.4 EMG49701.1 - 0.14 11.8 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Membrane-associated sensor domain SH3_9 PF14604.6 EMG49702.1 - 4.5e-09 36.0 0.1 7.7e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMG49702.1 - 9.3e-08 31.6 0.1 1.9e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMG49702.1 - 1.3e-06 28.0 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Aldo_ket_red PF00248.21 EMG49703.1 - 2.3e-42 145.2 0.0 7.3e-41 140.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SpoU_sub_bind PF08032.12 EMG49703.1 - 0.035 14.4 0.1 0.28 11.5 0.0 2.6 2 1 1 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Bul1_N PF04425.12 EMG49705.1 - 1.2e-88 297.8 2.8 3.2e-88 296.5 2.8 1.5 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 EMG49705.1 - 5.2e-21 75.3 8.2 4.6e-11 42.6 0.4 3.0 2 1 0 3 3 3 2 Bul1 C terminus Bul1_N PF04425.12 EMG49706.1 - 4.1e-95 319.2 0.2 9e-95 318.1 0.2 1.5 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 EMG49706.1 - 2.9e-25 89.2 7.8 8.2e-14 51.7 3.3 3.0 2 1 1 3 3 3 2 Bul1 C terminus DUF3665 PF12427.8 EMG49706.1 - 0.026 14.2 0.1 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase CsgA PF17334.2 EMG49706.1 - 0.037 14.8 2.5 8.1 7.3 0.3 2.6 2 0 0 2 2 2 0 Minor curli fiber component A PfkB PF00294.24 EMG49707.1 - 1.1e-58 198.9 0.1 1.4e-58 198.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EMG49707.1 - 9.6e-05 21.9 0.1 0.00015 21.3 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase RPA_C PF08784.11 EMG49707.1 - 0.024 15.3 0.7 0.2 12.3 0.1 2.4 2 1 0 2 2 2 0 Replication protein A C terminal DKCLD PF08068.12 EMG49708.1 - 5.1e-33 112.9 0.3 5.5e-32 109.6 0.3 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EMG49708.1 - 2.7e-23 81.9 0.5 5.2e-23 81.0 0.5 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EMG49708.1 - 2.6e-22 79.8 0.0 1.3e-19 71.0 0.0 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EMG49708.1 - 5.5e-21 74.3 0.6 1.1e-20 73.4 0.6 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EMG49708.1 - 0.00049 20.3 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain GAGA_bind PF06217.12 EMG49708.1 - 0.76 10.0 12.7 1.1 9.5 12.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CTNNB1_binding PF08347.11 EMG49708.1 - 8.3 6.5 11.3 15 5.7 11.3 1.4 1 0 0 1 1 1 0 N-terminal CTNNB1 binding HSF_DNA-bind PF00447.17 EMG49709.1 - 1.2e-28 99.5 2.4 1.2e-28 99.5 2.4 3.0 3 0 0 3 3 3 1 HSF-type DNA-binding DUF702 PF05142.12 EMG49709.1 - 2.9 8.3 6.7 9.7 6.7 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF3085 PF11284.8 EMG49710.1 - 0.047 14.0 0.0 0.053 13.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) AOX PF01786.17 EMG49711.1 - 6.6e-84 280.8 0.0 8e-84 280.5 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase AOX PF01786.17 EMG49712.1 - 1.8e-90 302.2 0.0 2.2e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF4248 PF14053.6 EMG49712.1 - 0.18 11.8 0.2 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) Dak1 PF02733.17 EMG49713.1 - 1.7e-101 339.2 0.1 2.8e-101 338.5 0.0 1.4 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 EMG49713.1 - 4.6e-47 160.1 0.2 9.4e-47 159.1 0.2 1.6 1 0 0 1 1 1 1 DAK2 domain DNA_pol3_delta PF06144.13 EMG49713.1 - 0.0032 17.3 0.1 0.0098 15.7 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit YmgD PF16456.5 EMG49713.1 - 0.1 12.7 1.2 21 5.3 0.2 3.3 3 0 0 3 3 3 0 YmgD protein K_oxygenase PF13434.6 EMG49714.1 - 3.1e-11 43.0 0.0 4.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMG49714.1 - 2.5e-08 33.5 0.0 1e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMG49714.1 - 0.017 14.7 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans_2 PF11951.8 EMG49715.1 - 1.9e-32 112.6 0.1 3.8e-31 108.3 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG49715.1 - 6.1e-08 32.7 11.5 1.2e-07 31.7 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EMG49716.1 - 1.6e-41 142.6 18.2 2.1e-41 142.3 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG49716.1 - 8.8e-23 80.8 28.9 3.3e-18 65.7 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EMG49717.1 - 4.2e-98 328.7 0.6 5.8e-98 328.2 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG49717.1 - 2.4e-09 37.2 7.0 3.8e-09 36.5 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLN_propep PF16485.5 EMG49717.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protealysin propeptide Flocculin_t3 PF13928.6 EMG49718.1 - 4e-15 56.0 15.2 4e-15 56.0 15.2 3.1 2 2 1 3 3 3 1 Flocculin type 3 repeat UCH_1 PF13423.6 EMG49719.1 - 7.2e-46 157.2 12.7 1.6e-45 156.1 12.7 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EMG49719.1 - 1.2e-19 71.4 0.0 3.1e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 EMG49719.1 - 2.3e-09 37.2 10.2 4.5e-09 36.2 10.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase eIF2A PF08662.11 EMG49719.1 - 0.0056 16.6 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A LVIVD PF08309.11 EMG49719.1 - 0.15 11.4 1.1 0.38 10.1 0.2 2.2 3 0 0 3 3 3 0 LVIVD repeat Ribosomal_L37e PF01907.19 EMG49720.1 - 2.2e-23 82.1 10.1 4e-23 81.3 10.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 EMG49720.1 - 0.003 17.6 0.4 0.0032 17.5 0.4 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 EMG49720.1 - 0.006 16.6 2.1 0.0085 16.1 2.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon Rubredoxin_2 PF18073.1 EMG49720.1 - 0.14 11.9 2.8 3.7 7.4 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain HypA PF01155.19 EMG49720.1 - 0.15 12.1 1.3 0.2 11.7 1.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1258 PF06869.12 EMG49720.1 - 0.22 10.9 4.0 0.17 11.4 2.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1258) zinc_ribbon_2 PF13240.6 EMG49720.1 - 0.34 10.7 4.7 6.1 6.7 0.7 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EMG49720.1 - 0.41 10.1 3.9 1.1 8.8 4.0 1.7 1 1 0 1 1 1 0 zinc-ribbon domain PAP2 PF01569.21 EMG49721.1 - 1.5e-25 89.5 0.4 1.5e-25 89.5 0.4 1.6 2 0 0 2 2 2 1 PAP2 superfamily TMEMspv1-c74-12 PF11044.8 EMG49721.1 - 0.16 12.0 7.0 3.1 7.9 1.3 3.6 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Fungal_trans_2 PF11951.8 EMG49722.1 - 2.1e-33 115.7 0.0 3e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG49722.1 - 8.2e-09 35.5 8.7 1.5e-08 34.7 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCD1 PF09798.9 EMG49723.1 - 8e-195 648.9 24.8 9.3e-195 648.7 24.8 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein CCDC53 PF10152.9 EMG49723.1 - 0.002 18.6 6.3 0.002 18.6 6.3 2.8 3 0 0 3 3 3 1 Subunit CCDC53 of WASH complex Fez1 PF06818.15 EMG49723.1 - 0.0022 18.5 2.1 0.0037 17.7 2.1 1.3 1 0 0 1 1 1 1 Fez1 NPHI_C PF08469.10 EMG49723.1 - 0.0041 17.1 0.4 0.011 15.7 0.4 1.7 1 0 0 1 1 1 1 Nucleoside triphosphatase I C-terminal TMF_TATA_bd PF12325.8 EMG49723.1 - 0.017 15.4 7.3 0.31 11.3 6.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Gp-FAR-1 PF05823.12 EMG49723.1 - 0.022 15.1 1.6 0.046 14.1 1.6 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Golgin_A5 PF09787.9 EMG49723.1 - 0.024 14.1 8.2 0.041 13.3 8.2 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 EMG49723.1 - 0.12 11.4 5.2 0.25 10.4 5.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YlqD PF11068.8 EMG49723.1 - 0.13 12.6 10.2 0.31 11.4 10.2 1.5 1 0 0 1 1 1 0 YlqD protein ACCA PF03255.14 EMG49723.1 - 0.33 10.8 6.1 0.41 10.5 3.5 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit EMG1 PF03587.14 EMG49724.1 - 4.6e-77 258.1 0.0 5.4e-77 257.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Tantalus PF15386.6 EMG49725.1 - 0.13 12.3 0.5 2.2 8.4 0.2 2.4 2 0 0 2 2 2 0 Drosophila Tantalus-like Pkinase PF00069.25 EMG49726.1 - 1.7e-73 247.3 0.0 5.1e-73 245.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49726.1 - 1.3e-37 129.5 0.0 2.3e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 EMG49726.1 - 3.1e-34 117.2 0.3 3.1e-34 117.2 0.3 2.1 2 0 0 2 2 2 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 EMG49726.1 - 1e-06 28.3 0.3 4.7e-05 22.9 0.0 2.7 3 0 0 3 3 3 1 Kinase-like PSI_PsaE PF02427.17 EMG49726.1 - 0.061 13.0 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE APH PF01636.23 EMG49726.1 - 0.066 13.1 2.1 0.14 12.0 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family KH_8 PF17903.1 EMG49727.1 - 4e-32 110.1 0.1 1.2e-31 108.6 0.1 1.8 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EMG49727.1 - 0.02 14.7 0.1 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 KH domain Med11 PF10280.9 EMG49728.1 - 0.021 15.3 1.1 0.1 13.1 0.0 2.6 2 0 0 2 2 2 0 Mediator complex protein HMMR_N PF15905.5 EMG49728.1 - 0.03 13.8 1.8 0.091 12.2 1.8 1.8 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Phage_HK97_TLTM PF06120.11 EMG49728.1 - 0.13 11.5 1.1 0.38 9.9 1.1 1.8 1 0 0 1 1 1 0 Tail length tape measure protein ANAPC4 PF12896.7 EMG49728.1 - 0.16 11.4 1.3 0.33 10.4 0.5 1.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Fib_alpha PF08702.10 EMG49728.1 - 1.8 8.7 8.6 0.6 10.3 1.7 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cor1 PF04803.12 EMG49728.1 - 2.6 8.3 5.1 29 4.9 0.5 2.9 2 1 1 3 3 3 0 Cor1/Xlr/Xmr conserved region MRC1 PF09444.10 EMG49729.1 - 2.2e-32 112.6 13.2 2.2e-32 112.6 13.2 8.3 8 2 0 8 8 8 1 MRC1-like domain S-AdoMet_synt_C PF02773.16 EMG49730.1 - 4e-67 224.4 0.4 8.1e-67 223.5 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EMG49730.1 - 1.8e-46 157.3 0.0 3.2e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EMG49730.1 - 1.2e-44 151.0 0.9 1.8e-44 150.5 0.2 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EMG49730.1 - 0.03 13.1 0.4 0.13 11.0 0.2 2.0 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Rad60-SLD PF11976.8 EMG49732.1 - 5.8e-18 64.5 0.3 7.6e-18 64.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EMG49732.1 - 1.2e-07 31.4 0.1 1.5e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family SH3_1 PF00018.28 EMG49732.1 - 0.14 11.8 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 SH3 domain Collagen_mid PF15984.5 EMG49733.1 - 0.099 12.4 1.5 0.29 10.9 0.1 2.1 2 0 0 2 2 2 0 Bacterial collagen, middle region FHA PF00498.26 EMG49734.1 - 0.0016 18.7 0.1 0.0067 16.8 0.1 2.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EMG49734.1 - 0.056 13.8 0.0 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain EB1 PF03271.17 EMG49735.1 - 1.3e-12 47.7 2.1 1.5e-12 47.5 0.3 2.1 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 EMG49735.1 - 1.6e-07 31.5 0.4 3.1e-07 30.5 0.4 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 EMG49735.1 - 0.0027 17.8 0.4 0.0058 16.7 0.4 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein Suf PF05843.14 EMG49735.1 - 0.0091 16.0 3.2 0.012 15.7 3.2 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) NHR2 PF08788.11 EMG49735.1 - 0.026 14.3 0.1 0.069 12.9 0.1 1.7 1 0 0 1 1 1 0 NHR2 domain like Plasmodium_Vir PF05795.11 EMG49736.1 - 0.35 10.2 9.0 0.46 9.8 9.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nop14 PF04147.12 EMG49736.1 - 0.38 8.9 10.9 0.46 8.6 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EMG49736.1 - 0.84 7.7 4.7 0.97 7.5 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 EMG49736.1 - 0.93 8.8 18.3 1.2 8.4 18.3 1.0 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 EMG49736.1 - 2.2 8.1 5.4 3.7 7.4 5.4 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 EMG49736.1 - 3.2 7.1 14.9 4 6.8 14.9 1.1 1 0 0 1 1 1 0 SDA1 DUF572 PF04502.13 EMG49736.1 - 3.5 7.2 8.5 4.2 6.9 8.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.7 EMG49736.1 - 5.9 4.9 12.3 6.4 4.8 12.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Utp14 PF04615.13 EMG49736.1 - 6.2 5.3 13.5 7.2 5.0 13.5 1.0 1 0 0 1 1 1 0 Utp14 protein Torus PF16131.5 EMG49737.1 - 9e-31 106.8 0.1 9e-31 106.8 0.1 2.1 2 1 0 2 2 2 1 Torus domain RRM_1 PF00076.22 EMG49737.1 - 0.036 13.9 0.1 0.1 12.4 0.1 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAPA-1 PF04795.12 EMG49737.1 - 0.26 12.1 6.7 0.66 10.8 6.7 1.7 1 0 0 1 1 1 0 PAPA-1-like conserved region zf-CCCH_4 PF18044.1 EMG49737.1 - 1.3 8.9 7.7 2.8 7.8 7.7 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger Oxidored_FMN PF00724.20 EMG49738.1 - 4.9e-43 147.7 0.0 6e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DEAD PF00270.29 EMG49739.1 - 1.2e-49 168.4 0.0 3.1e-49 167.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG49739.1 - 6.1e-29 100.6 0.3 1.9e-28 99.0 0.3 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG49739.1 - 6.8e-06 26.2 1.2 5.5e-05 23.2 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EMG49739.1 - 0.00024 20.4 0.2 0.0024 17.1 0.1 2.1 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase PRAI PF00697.22 EMG49739.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase PSP1 PF04468.12 EMG49740.1 - 2.9e-29 101.2 2.3 9.1e-29 99.6 2.3 1.9 1 0 0 1 1 1 1 PSP1 C-terminal conserved region CDP-OH_P_transf PF01066.21 EMG49742.1 - 2.7e-12 47.3 0.6 2.7e-12 47.3 0.6 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase BHD_1 PF10403.9 EMG49743.1 - 0.077 12.9 2.5 45 4.0 0.0 4.4 5 0 0 5 5 5 0 Rad4 beta-hairpin domain 1 Nitr_red_alph_N PF14710.6 EMG49743.1 - 8.5 6.9 5.8 1.6 9.3 0.1 2.5 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal Hap4_Hap_bind PF10297.9 EMG49744.1 - 7.2e-09 35.5 7.3 1.8e-08 34.2 7.3 1.8 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EMG49744.1 - 0.00011 22.3 19.6 0.0072 16.4 14.1 2.8 1 1 1 2 2 2 2 bZIP transcription factor dsrm PF00035.26 EMG49744.1 - 0.12 13.1 0.0 0.52 11.1 0.0 2.1 1 0 0 1 1 1 0 Double-stranded RNA binding motif bZIP_2 PF07716.15 EMG49744.1 - 0.15 12.1 22.0 0.2 11.8 11.2 3.0 1 1 1 2 2 2 0 Basic region leucine zipper TMF_DNA_bd PF12329.8 EMG49744.1 - 5.8 7.0 13.7 2.2 8.4 4.8 3.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding NIF PF03031.18 EMG49745.1 - 1.7e-41 141.6 0.1 2.7e-41 141.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ARD PF03079.14 EMG49747.1 - 1.1e-41 142.6 2.7 1.3e-41 142.4 2.7 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EMG49747.1 - 1.2e-08 34.5 0.0 2.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EMG49747.1 - 4.6e-06 26.6 0.0 7.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EMG49747.1 - 0.0021 17.7 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Cupin DUF5380 PF17351.2 EMG49747.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5380) BAR_2 PF10455.9 EMG49748.1 - 1.4e-95 319.8 10.4 1.6e-95 319.5 10.4 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EMG49748.1 - 1.1e-09 38.3 5.6 3.1e-09 36.8 1.6 2.5 2 1 0 2 2 2 1 BAR domain HSP9_HSP12 PF04119.12 EMG49748.1 - 0.011 16.2 0.7 0.028 14.8 0.7 1.8 1 0 0 1 1 1 0 Heat shock protein 9/12 RPN6_N PF18055.1 EMG49748.1 - 0.063 13.6 3.5 0.11 12.9 0.3 2.7 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Glyco_transf_24 PF18404.1 EMG49748.1 - 0.081 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Glucosyltransferase 24 Nucleoporin_FG2 PF15967.5 EMG49748.1 - 0.083 11.4 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeated region OST-HTH PF12872.7 EMG49748.1 - 0.11 12.4 0.0 12 5.8 0.0 2.9 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Fib_alpha PF08702.10 EMG49748.1 - 2.3 8.4 8.5 0.19 11.9 0.9 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PRP38 PF03371.15 EMG49749.1 - 2.4e-51 174.1 1.6 2.8e-51 173.8 1.6 1.1 1 0 0 1 1 1 1 PRP38 family EamA PF00892.20 EMG49750.1 - 3.3e-10 40.3 36.8 6e-06 26.5 20.7 2.8 2 1 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 EMG49750.1 - 2.2e-08 33.5 12.5 3.9e-08 32.7 12.5 1.4 1 1 0 1 1 1 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 EMG49750.1 - 0.071 12.3 10.8 0.18 10.9 10.7 1.9 1 1 0 1 1 1 0 Nucleotide-sugar transporter ISK_Channel PF02060.15 EMG49750.1 - 0.33 10.7 2.5 1.1 9.0 1.1 2.2 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Nas2_N PF18265.1 EMG49751.1 - 4.8e-23 80.9 0.6 1e-22 79.8 0.6 1.6 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 EMG49751.1 - 1.1e-07 32.0 0.1 2.4e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EMG49751.1 - 0.0014 19.0 0.0 0.003 17.9 0.0 1.6 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EMG49751.1 - 0.0015 18.3 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DDOST_48kD PF03345.14 EMG49752.1 - 4.2e-111 371.7 2.8 4.2e-110 368.4 2.8 1.9 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Zn_peptidase_2 PF04298.12 EMG49752.1 - 0.035 13.5 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Arf PF00025.21 EMG49753.1 - 7e-37 126.5 3.7 2.5e-28 98.7 0.3 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 EMG49753.1 - 1e-13 51.2 2.1 1.3e-07 31.2 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EMG49753.1 - 2.6e-10 40.5 3.3 2.8e-08 34.0 0.7 2.6 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EMG49753.1 - 2.1e-09 37.2 0.7 2.8e-08 33.5 0.1 2.3 1 1 1 2 2 2 1 Ras family SRPRB PF09439.10 EMG49753.1 - 1.3e-07 31.2 3.8 0.00076 19.0 0.0 2.8 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EMG49753.1 - 2.2e-07 30.6 0.0 4.5e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMG49753.1 - 3.8e-07 30.2 0.3 9.2e-07 28.9 0.3 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EMG49753.1 - 3.4e-06 26.6 0.2 9.8e-06 25.1 0.2 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EMG49753.1 - 0.0015 18.8 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMG49753.1 - 0.011 15.5 4.3 0.014 15.1 4.3 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EMG49753.1 - 0.015 15.8 1.9 0.028 14.9 1.9 1.3 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EMG49753.1 - 0.024 13.9 0.3 0.04 13.2 0.3 1.4 1 0 0 1 1 1 0 Septin TniB PF05621.11 EMG49753.1 - 0.05 13.0 0.0 0.73 9.2 0.0 2.4 2 1 1 3 3 3 0 Bacterial TniB protein AAA_18 PF13238.6 EMG49753.1 - 0.12 13.0 0.1 0.2 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 EMG49754.1 - 1.2e-45 155.5 8.9 1.2e-45 155.5 8.9 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 EMG49754.1 - 1.5e-05 25.2 0.0 3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EMG49754.1 - 9.3e-05 22.0 6.1 0.00022 20.8 0.7 2.9 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EMG49754.1 - 0.00021 21.8 0.1 0.0007 20.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EMG49754.1 - 0.00042 20.8 0.0 0.00076 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMG49754.1 - 0.0056 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMG49754.1 - 0.0074 16.7 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EMG49754.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ADK PF00406.22 EMG49754.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Adenylate kinase NB-ARC PF00931.22 EMG49754.1 - 0.014 14.6 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Arf PF00025.21 EMG49754.1 - 0.02 14.4 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family T2SSE PF00437.20 EMG49754.1 - 0.032 13.3 0.1 0.052 12.6 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein APS_kinase PF01583.20 EMG49754.1 - 0.035 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.6 EMG49754.1 - 0.06 13.4 1.7 1.2 9.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EMG49754.1 - 0.12 12.5 0.6 0.66 10.1 0.6 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase WD40 PF00400.32 EMG49755.1 - 1.9e-30 104.5 16.3 4e-07 30.6 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG49755.1 - 2.3e-15 56.7 0.9 0.0059 16.9 0.1 5.6 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMG49755.1 - 3.2e-08 33.7 1.9 0.0077 16.1 0.2 3.7 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EMG49755.1 - 0.0006 19.2 0.1 0.055 12.8 0.1 2.2 2 0 0 2 2 2 2 WD40-like domain Nbas_N PF15492.6 EMG49755.1 - 0.07 12.5 0.2 4.4 6.6 0.0 3.1 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal NTF2 PF02136.20 EMG49755.1 - 0.077 13.6 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain SWIRM PF04433.17 EMG49756.1 - 6.1e-14 52.1 0.7 2.2e-13 50.4 0.0 2.3 2 1 0 2 2 2 1 SWIRM domain ZZ PF00569.17 EMG49756.1 - 4.3e-13 48.8 7.9 7.9e-13 48.0 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 EMG49756.1 - 7.1e-12 45.3 0.3 2.1e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMG49756.1 - 5e-07 29.9 0.7 9.8e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Baculo_IE-1 PF05290.11 EMG49756.1 - 0.21 11.5 2.9 0.58 10.1 2.9 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) TLD PF07534.16 EMG49757.1 - 3.2e-25 89.0 3.2 1.7e-22 80.2 3.5 2.3 1 1 1 2 2 2 2 TLD NUC153 PF08159.12 EMG49758.1 - 3.9e-14 52.1 2.7 3.9e-14 52.1 2.7 3.2 3 0 0 3 3 3 2 NUC153 domain HLH PF00010.26 EMG49760.1 - 6.3e-14 51.7 0.9 1.6e-13 50.4 0.9 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cgr1 PF03879.14 EMG49761.1 - 1.9e-31 108.6 28.1 2.2e-31 108.4 28.1 1.0 1 0 0 1 1 1 1 Cgr1 family Pex24p PF06398.11 EMG49762.1 - 2.3e-77 260.5 15.8 2.8e-77 260.2 15.8 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin FAD_binding_8 PF08022.12 EMG49763.1 - 6.9e-24 84.0 0.2 1.3e-23 83.1 0.2 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EMG49763.1 - 4.8e-20 71.9 17.2 2.3e-19 69.7 14.2 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMG49763.1 - 1.3e-18 67.7 0.0 2.7e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ribosomal_L7Ae PF01248.26 EMG49764.1 - 3.4e-23 81.2 0.7 5.7e-23 80.5 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EMG49764.1 - 0.0033 17.5 0.1 0.0052 16.8 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 EF-hand_like PF09279.11 EMG49764.1 - 0.11 13.0 0.2 0.69 10.4 0.1 2.0 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like RRM_1 PF00076.22 EMG49765.1 - 2e-10 40.3 1.5 1.8e-08 34.0 0.1 3.6 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EMG49765.1 - 0.021 15.1 1.2 3.1 8.0 0.0 3.0 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_L2_C PF03947.18 EMG49766.1 - 1.5e-42 144.8 4.1 1.5e-42 144.8 4.1 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EMG49766.1 - 4.8e-15 55.3 0.1 1.3e-14 53.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_S17e PF00833.18 EMG49767.1 - 9e-56 187.1 0.5 1.1e-55 186.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal S17 UPF0262 PF06793.12 EMG49767.1 - 0.007 16.5 0.1 0.041 14.0 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0262) Exotox-A_cataly PF09009.10 EMG49767.1 - 0.069 12.9 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A catalytic MIR PF02815.19 EMG49767.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 MIR domain Pet127 PF08634.10 EMG49768.1 - 1.5e-102 342.7 1.5 1.5e-102 342.7 1.5 2.3 2 0 0 2 2 2 1 Mitochondrial protein Pet127 DUF2977 PF11192.8 EMG49768.1 - 0.048 13.8 0.0 0.25 11.5 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2977) U3_assoc_6 PF08640.11 EMG49769.1 - 7.8e-31 106.0 3.9 8e-30 102.8 0.1 2.7 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Suf PF05843.14 EMG49769.1 - 0.0065 16.5 1.8 0.9 9.5 0.0 3.0 1 1 2 3 3 3 1 Suppressor of forked protein (Suf) DUF2704 PF10866.8 EMG49769.1 - 0.007 16.3 2.2 0.019 14.9 2.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2704) TPR_14 PF13428.6 EMG49769.1 - 0.038 14.8 0.0 8.1 7.6 0.0 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat DUF2250 PF10007.9 EMG49769.1 - 0.066 13.3 7.8 20 5.4 0.0 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2250) RIO1 PF01163.22 EMG49771.1 - 2e-73 246.0 1.3 2e-73 246.0 1.3 2.2 2 0 0 2 2 2 1 RIO1 family EMP24_GP25L PF01105.24 EMG49771.1 - 4.2e-44 150.7 2.3 4.2e-44 150.7 2.3 1.9 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD CDC45 PF02724.14 EMG49771.1 - 0.0029 16.0 23.0 0.0051 15.2 23.0 1.3 1 0 0 1 1 1 1 CDC45-like protein APH PF01636.23 EMG49771.1 - 0.022 14.7 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family YL1 PF05764.13 EMG49771.1 - 0.16 12.1 34.7 0.015 15.5 26.6 2.2 2 0 0 2 2 2 0 YL1 nuclear protein ThiF PF00899.21 EMG49772.1 - 1.1e-55 188.6 0.0 1.6e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EMG49772.1 - 9.8e-14 51.8 0.0 3.7e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 EMG49772.1 - 0.012 15.7 0.0 0.048 13.7 0.0 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Herpes_BLRF2 PF05812.12 EMG49772.1 - 0.022 14.9 0.2 0.055 13.6 0.2 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein PglD_N PF17836.1 EMG49772.1 - 0.029 15.0 0.2 0.074 13.7 0.2 1.7 1 0 0 1 1 1 0 PglD N-terminal domain NAD_binding_7 PF13241.6 EMG49772.1 - 0.078 13.4 0.0 0.24 11.9 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding TSC22 PF01166.18 EMG49772.1 - 0.15 12.4 0.5 0.36 11.2 0.5 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Rad60-SLD PF11976.8 EMG49774.1 - 7.5e-22 77.0 4.2 9.3e-22 76.7 2.1 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EMG49774.1 - 0.0036 17.0 0.4 0.0098 15.6 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 EMG49774.1 - 0.0057 16.8 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 TUG ubiquitin-like domain Cobl PF09469.10 EMG49774.1 - 0.045 14.0 0.2 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain RBD PF02196.15 EMG49774.1 - 0.11 12.6 0.2 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Raf-like Ras-binding domain Kei1 PF08552.11 EMG49775.1 - 1.7e-09 37.9 0.7 2.3e-09 37.4 0.7 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF475 PF04332.15 EMG49775.1 - 0.018 14.8 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF475) MRP-S25 PF13741.6 EMG49776.1 - 2.8e-96 321.5 4.8 3.4e-96 321.3 4.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EMG49776.1 - 5e-09 36.5 0.2 2.2e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial ribosomal protein S23 Nipped-B_C PF12830.7 EMG49777.1 - 0.23 11.4 1.7 0.66 9.9 0.0 2.5 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus DAO PF01266.24 EMG49779.1 - 5.8e-71 239.9 0.0 6.8e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMG49779.1 - 6.8e-06 26.2 0.3 1.9e-05 24.8 0.3 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 EMG49779.1 - 0.0011 17.8 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 MCRA family NAD_binding_9 PF13454.6 EMG49779.1 - 0.0016 18.4 0.2 0.014 15.3 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EMG49779.1 - 0.0024 17.2 0.1 0.004 16.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EMG49779.1 - 0.0044 16.3 0.0 0.049 12.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CDC45 PF02724.14 EMG49779.1 - 0.025 12.9 9.0 0.035 12.4 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sacchrp_dh_NADP PF03435.18 EMG49779.1 - 0.083 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 EMG49779.1 - 0.16 10.8 0.1 0.26 10.1 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase BUD22 PF09073.10 EMG49779.1 - 0.23 10.8 15.6 0.44 9.8 15.6 1.4 1 0 0 1 1 1 0 BUD22 DUF2076 PF09849.9 EMG49779.1 - 0.42 10.6 6.6 0.68 9.9 6.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pes-10 PF07149.11 EMG49779.1 - 0.45 9.5 7.0 0.77 8.8 7.0 1.3 1 0 0 1 1 1 0 Pes-10 RRN3 PF05327.11 EMG49779.1 - 0.79 8.2 5.3 1.1 7.7 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-C2H2 PF00096.26 EMG49780.1 - 2e-13 50.0 12.2 3e-06 27.4 1.7 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG49780.1 - 2.6e-08 34.0 12.8 0.00028 21.5 1.3 3.2 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMG49780.1 - 8.5e-08 32.3 12.7 7.8e-06 26.1 4.4 3.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EMG49780.1 - 3.4e-05 24.0 8.8 0.0014 18.8 1.0 4.9 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EMG49780.1 - 0.00017 21.5 13.2 0.0013 18.7 1.5 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EMG49780.1 - 0.034 13.9 12.3 0.072 12.9 2.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.15 EMG49780.1 - 0.044 13.8 0.3 0.044 13.8 0.3 3.0 3 0 0 3 3 2 0 BED zinc finger zf_C2H2_ZHX PF18387.1 EMG49780.1 - 0.17 11.5 4.6 0.47 10.1 0.6 2.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain PyrI_C PF02748.15 EMG49780.1 - 0.21 11.5 2.1 0.59 10.1 0.4 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HE PF16278.5 EMG49780.1 - 0.24 11.9 9.4 1.7 9.1 1.1 2.9 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Evr1_Alr PF04777.13 EMG49780.1 - 0.25 11.8 4.5 7 7.2 0.4 3.4 1 1 1 2 2 2 0 Erv1 / Alr family zf-Di19 PF05605.12 EMG49780.1 - 0.38 11.1 3.2 0.89 9.9 3.2 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 EMG49780.1 - 3.2 7.4 6.0 11 5.7 0.3 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger G6PD_C PF02781.16 EMG49781.1 - 8.3e-111 369.8 0.0 1.1e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EMG49781.1 - 3.4e-58 197.2 0.0 6e-58 196.4 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ish1 PF10281.9 EMG49781.1 - 0.1 12.9 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein 6PF2K PF01591.18 EMG49783.1 - 3.6e-78 261.9 0.1 1.1e-77 260.4 0.0 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EMG49783.1 - 1.8e-29 102.8 0.0 3.1e-23 82.5 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EMG49783.1 - 0.007 16.5 0.1 0.025 14.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain NICE-3 PF07406.11 EMG49783.1 - 0.082 12.9 0.2 0.27 11.2 0.2 1.8 1 0 0 1 1 1 0 NICE-3 protein Fe_hyd_lg_C PF02906.14 EMG49784.1 - 1.5e-63 214.7 0.0 2.4e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2284 PF10050.9 EMG49784.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Ytp1 PF10355.9 EMG49785.1 - 5.2e-64 216.1 16.9 3.1e-62 210.3 16.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) Peptidase_S8 PF00082.22 EMG49786.1 - 2.5e-36 125.5 3.5 2.5e-36 125.5 3.5 1.7 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 EMG49786.1 - 1e-20 73.5 0.1 2.8e-20 72.1 0.1 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain SARAF PF06682.12 EMG49786.1 - 0.051 13.2 0.9 0.11 12.1 0.9 1.6 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Orf78 PF06024.12 EMG49786.1 - 0.53 10.6 0.0 0.53 10.6 0.0 3.5 4 0 0 4 4 4 0 Orf78 (ac78) RNA_pol_Rpb1_5 PF04998.17 EMG49787.1 - 1.1e-97 326.6 4.5 1.3e-67 228.0 0.2 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EMG49787.1 - 3.1e-70 235.7 0.1 7.5e-70 234.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EMG49787.1 - 5.3e-38 130.4 0.6 8.8e-37 126.5 0.0 3.4 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EMG49787.1 - 1.1e-25 90.7 1.4 1.1e-25 90.7 1.4 2.7 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EMG49787.1 - 1.9e-24 85.7 0.1 1.8e-23 82.6 0.1 2.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Herpes_UL69 PF05459.12 EMG49787.1 - 0.11 11.8 0.1 1.2 8.4 0.0 2.5 3 0 0 3 3 3 0 Herpesvirus transcriptional regulator family SIR2 PF02146.17 EMG49788.1 - 1.6e-63 213.8 0.0 2.4e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EMG49788.1 - 2.9e-24 85.6 2.7 2e-12 47.1 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EMG49788.1 - 0.0008 19.2 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PNISR PF15996.5 EMG49788.1 - 1.1 9.5 4.6 1.7 8.9 4.6 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Methyltransf_16 PF10294.9 EMG49789.1 - 9.3e-06 25.5 0.0 0.00095 18.9 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EMG49789.1 - 0.0073 16.2 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CRISPR_Cas2 PF09827.9 EMG49789.1 - 0.11 12.7 0.1 0.32 11.2 0.1 1.7 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Methyltransf_31 PF13847.6 EMG49789.1 - 0.11 12.3 0.3 1.2 8.9 0.0 2.5 2 1 1 3 3 3 0 Methyltransferase domain COX4 PF02936.14 EMG49790.1 - 5.9e-29 100.9 0.0 7.1e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV N1221 PF07923.13 EMG49790.1 - 0.073 12.3 0.0 0.073 12.3 0.0 1.1 1 0 0 1 1 1 0 N1221-like protein Fer4 PF00037.27 EMG49791.1 - 9.2e-14 50.6 17.0 3.7e-08 32.8 4.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EMG49791.1 - 5.8e-13 49.2 10.3 1.2e-12 48.2 10.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMG49791.1 - 2.6e-10 40.2 21.0 3.8e-07 30.1 11.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EMG49791.1 - 9.4e-10 39.3 12.2 3.8e-05 24.5 1.4 2.6 2 1 1 3 3 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 EMG49791.1 - 3.7e-09 36.6 21.8 1.2e-07 31.7 11.0 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EMG49791.1 - 7e-09 35.7 32.1 1.1e-05 25.5 12.6 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 EMG49791.1 - 1.3e-07 31.9 9.3 7.9e-05 23.0 1.0 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EMG49791.1 - 1.6e-06 27.9 17.5 0.0004 20.3 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EMG49791.1 - 2.1e-06 27.5 11.3 0.0058 16.7 1.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EMG49791.1 - 1.9e-05 24.8 11.5 0.0003 21.1 1.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EMG49791.1 - 7.6e-05 23.2 11.7 0.019 15.5 2.2 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EMG49791.1 - 0.036 14.3 6.8 0.48 10.7 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 EMG49791.1 - 0.044 14.3 15.4 0.75 10.4 4.3 2.8 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 EMG49791.1 - 0.06 13.5 5.2 0.2 11.8 0.3 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 EMG49791.1 - 0.061 14.3 15.7 0.12 13.4 3.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 EMG49791.1 - 0.062 13.5 9.1 0.93 9.7 1.3 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EMG49791.1 - 0.3 12.0 11.4 0.81 10.6 1.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain C2 PF00168.30 EMG49792.1 - 2.2e-64 214.2 1.5 8.8e-20 70.9 0.0 4.6 4 0 0 4 4 4 4 C2 domain RR_TM4-6 PF06459.12 EMG49792.1 - 0.035 13.9 8.9 0.065 13.1 8.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PDCD2_C PF04194.13 EMG49792.1 - 0.06 13.4 9.7 0.12 12.5 9.7 1.4 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain CSRNP_N PF16019.5 EMG49792.1 - 0.26 11.2 5.5 0.47 10.3 5.5 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Vfa1 PF08432.10 EMG49792.1 - 2.4 8.5 13.6 5 7.4 13.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.6 EMG49792.1 - 2.6 7.3 4.9 4.1 6.7 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNA_pol_Rpc4 PF05132.14 EMG49792.1 - 6.7 7.1 11.8 0.051 14.0 2.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4746 PF15928.5 EMG49792.1 - 6.8 6.0 14.4 15 4.9 14.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Abhydrolase_1 PF00561.20 EMG49793.1 - 4.7e-22 78.9 0.0 6.1e-21 75.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMG49793.1 - 2.7e-13 51.1 0.0 5.2e-13 50.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMG49793.1 - 1.8e-08 34.0 0.0 3.4e-08 33.1 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EMG49793.1 - 0.003 17.3 0.0 0.48 10.1 0.0 2.3 1 1 1 2 2 2 2 PGAP1-like protein Chlorophyllase2 PF12740.7 EMG49793.1 - 0.0035 16.3 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 EMG49793.1 - 0.033 14.0 0.0 0.041 13.7 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EMG49793.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 EMG49793.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 EMG49793.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family CN_hydrolase PF00795.22 EMG49794.1 - 1.3e-45 155.8 0.0 1.5e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GspH PF12019.8 EMG49794.1 - 0.079 13.4 0.0 6.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Type II transport protein GspH YoaP PF14268.6 EMG49794.1 - 0.13 11.8 0.5 0.33 10.5 0.5 1.6 1 0 0 1 1 1 0 YoaP-like TPX2 PF06886.11 EMG49795.1 - 1.1 9.5 9.0 14 6.0 0.0 2.8 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Csm1_N PF18504.1 EMG49795.1 - 1.4 9.4 11.2 6.1 7.3 0.0 4.5 5 0 0 5 5 5 0 Csm1 N-terminal domain Cohesin_load PF10345.9 EMG49796.1 - 7.7e-74 249.2 29.5 1.2e-73 248.5 29.5 1.3 1 0 0 1 1 1 1 Cohesin loading factor TPR_8 PF13181.6 EMG49796.1 - 0.0026 17.8 12.8 0.095 13.0 1.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMG49796.1 - 1.3 9.3 10.4 37 4.8 2.5 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PFU PF09070.11 EMG49796.1 - 5.7 7.2 7.8 0.59 10.4 0.1 3.3 5 0 0 5 5 5 0 PFU (PLAA family ubiquitin binding) Myotub-related PF06602.14 EMG49797.1 - 2e-144 480.9 0.4 2.5e-144 480.6 0.4 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain TALPID3 PF15324.6 EMG49797.1 - 0.023 12.4 0.4 0.05 11.3 0.4 1.4 1 1 0 1 1 1 0 Hedgehog signalling target DSPc PF00782.20 EMG49797.1 - 0.023 14.5 0.6 0.063 13.1 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMG49797.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EMG49797.1 - 0.035 14.1 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family GRAM PF02893.20 EMG49797.1 - 0.042 13.7 0.5 0.34 10.8 0.0 2.7 3 0 0 3 3 3 0 GRAM domain Paramyxo_P_V_N PF13825.6 EMG49797.1 - 1.1 8.7 6.7 0.056 12.9 1.2 1.6 2 0 0 2 2 2 0 Paramyxovirus structural protein V/P N-terminus SDA1 PF05285.12 EMG49798.1 - 0.00013 21.5 20.6 0.00013 21.5 20.6 1.6 2 0 0 2 2 2 1 SDA1 WD40 PF00400.32 EMG49798.1 - 0.018 15.9 3.0 0.18 12.8 0.1 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat CDC45 PF02724.14 EMG49798.1 - 1.8 6.7 15.3 3.3 5.9 15.3 1.4 1 0 0 1 1 1 0 CDC45-like protein Amino_oxidase PF01593.24 EMG49799.1 - 7.6e-14 51.8 0.0 9.3e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMG49799.1 - 7.2e-13 48.6 0.0 1.5e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMG49799.1 - 4.9e-05 22.7 0.0 0.00014 21.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EMG49799.1 - 0.0007 19.3 0.0 0.0042 16.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMG49799.1 - 0.00078 20.0 0.1 0.39 11.3 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EMG49799.1 - 0.0014 17.2 0.0 0.0097 14.5 0.0 2.0 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 EMG49799.1 - 0.11 11.7 0.0 0.41 9.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TBP PF00352.21 EMG49800.1 - 8.1e-67 221.2 0.1 7.6e-33 112.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EMG49800.1 - 3e-05 24.1 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EMG49800.1 - 0.043 13.6 0.1 0.26 11.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ABC_membrane PF00664.23 EMG49801.1 - 3.6e-66 223.6 40.4 8.2e-38 130.6 13.3 2.8 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMG49801.1 - 2.5e-49 167.3 0.2 1e-26 94.1 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 EMG49801.1 - 2e-10 40.5 12.5 0.00032 20.2 3.3 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EMG49801.1 - 4.9e-07 29.8 0.0 0.00083 19.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMG49801.1 - 1.5e-06 28.3 1.1 0.08 13.0 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EMG49801.1 - 3.5e-06 27.6 3.9 0.01 16.3 0.3 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EMG49801.1 - 7.1e-06 25.7 1.0 0.0058 16.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EMG49801.1 - 1.9e-05 24.6 2.9 0.02 14.7 0.0 3.5 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMG49801.1 - 7.2e-05 23.2 0.5 0.54 10.6 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 EMG49801.1 - 0.0044 16.8 2.5 0.066 12.9 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_7 PF12775.7 EMG49801.1 - 0.025 14.1 0.2 5 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EMG49801.1 - 0.033 13.9 0.0 2.6 7.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 EMG49801.1 - 0.037 14.1 3.7 1.9 8.5 0.2 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_22 PF13401.6 EMG49801.1 - 0.037 14.3 6.4 0.91 9.8 0.0 3.9 3 1 0 3 3 3 0 AAA domain MeaB PF03308.16 EMG49801.1 - 0.047 12.7 0.1 4.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 EMG49801.1 - 0.053 12.7 0.2 3.5 6.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 EMG49801.1 - 0.064 13.0 4.0 5.2 6.7 0.1 3.0 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EMG49801.1 - 0.065 12.0 1.6 4.9 5.8 0.3 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF815 PF05673.13 EMG49801.1 - 0.085 12.0 0.0 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 EMG49801.1 - 0.11 12.5 0.4 3.9 7.5 0.0 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EMG49801.1 - 0.13 11.3 0.5 13 4.7 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein Dynamin_N PF00350.23 EMG49801.1 - 0.21 11.6 5.7 0.26 11.3 0.1 2.9 3 0 0 3 3 2 0 Dynamin family AAA_27 PF13514.6 EMG49801.1 - 0.24 10.9 0.7 1.4 8.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EMG49801.1 - 0.6 9.8 5.4 4 7.1 0.1 3.1 3 1 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 EMG49801.1 - 3.2 7.5 5.4 9.5 5.9 0.2 2.9 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein HhH-GPD PF00730.25 EMG49802.1 - 2.2e-19 69.9 0.0 3.6e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EMG49802.1 - 7.8e-06 25.5 0.0 1.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Fungal_trans PF04082.18 EMG49803.1 - 1.3e-39 135.9 1.0 2.6e-39 134.9 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG49803.1 - 1.3e-10 41.2 11.0 2.3e-10 40.4 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 EMG49803.1 - 0.021 14.9 1.2 0.021 14.9 1.2 2.3 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 EMG49803.1 - 0.098 12.8 0.7 0.38 10.9 0.7 2.0 1 0 0 1 1 1 0 Basic region leucine zipper Oxysterol_BP PF01237.18 EMG49804.1 - 1.6e-125 418.9 0.0 1.6e-125 418.9 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 EMG49804.1 - 2.4e-15 56.9 0.5 7.5e-11 42.5 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMG49804.1 - 9.4e-14 51.3 0.2 7.7e-06 26.1 0.1 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMG49804.1 - 8.2e-13 47.3 0.3 0.00066 19.9 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EMG49804.1 - 1.6e-12 47.6 0.1 5.4e-09 36.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EMG49804.1 - 4.4e-09 36.4 0.3 0.00076 19.8 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.29 EMG49804.1 - 2.2e-08 34.6 0.1 7e-08 32.9 0.1 2.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EMG49804.1 - 1.4e-07 31.7 0.3 4e-07 30.2 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3772 PF12607.8 EMG49804.1 - 0.077 12.8 0.9 0.78 9.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) CRAL_TRIO PF00650.20 EMG49805.1 - 5.8e-20 71.6 0.0 8.2e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMG49805.1 - 0.0039 17.3 0.0 0.0094 16.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Mannosyl_trans3 PF11051.8 EMG49806.1 - 1.6e-84 283.5 0.1 2.5e-84 282.9 0.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative MFS_1 PF07690.16 EMG49807.1 - 2.4e-33 115.5 47.3 6.3e-33 114.1 44.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG49807.1 - 5.8e-05 22.1 14.7 5.8e-05 22.1 14.7 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter Exo_endo_phos PF03372.23 EMG49808.1 - 8.7e-12 45.1 0.1 1.2e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EMG49808.1 - 3.3e-05 23.7 0.1 0.3 11.0 0.0 2.6 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Med15_fungi PF05397.12 EMG49809.1 - 2.1e-35 121.4 0.8 2.1e-35 121.4 0.8 8.4 7 3 2 9 9 9 1 Mediator complex subunit 15 KIX_2 PF16987.5 EMG49809.1 - 1e-21 76.7 0.8 1e-21 76.7 0.8 4.5 4 0 0 4 4 4 1 KIX domain U3_assoc_6 PF08640.11 EMG49809.1 - 6.7 6.9 8.5 0.47 10.5 1.7 2.6 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 WD40 PF00400.32 EMG49810.1 - 1.2e-49 165.2 24.5 2.1e-06 28.4 0.3 11.5 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG49810.1 - 1.5e-19 70.0 4.1 1.3e-05 25.3 0.0 9.8 4 2 7 11 11 11 8 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EMG49810.1 - 7.2e-18 64.9 0.7 1.4e-17 63.9 0.7 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 EMG49810.1 - 3e-07 29.5 2.3 0.31 9.6 0.1 4.9 4 1 1 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EMG49810.1 - 0.00014 21.4 18.0 0.016 14.5 7.3 5.8 5 1 0 5 5 5 1 WD40-like domain PALB2_WD40 PF16756.5 EMG49810.1 - 0.0063 15.5 2.8 4.1 6.2 0.0 4.6 4 1 1 5 5 5 1 Partner and localizer of BRCA2 WD40 domain PLA2_B PF01735.18 EMG49811.1 - 1.4e-184 614.1 3.8 1.9e-184 613.7 3.8 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 EMG49811.1 - 0.0058 16.8 2.2 0.013 15.8 2.2 1.5 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain His_Phos_1 PF00300.22 EMG49812.1 - 2.4e-07 30.6 0.2 5.6e-07 29.4 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Exo_endo_phos PF03372.23 EMG49813.1 - 1.3e-22 80.4 0.0 3.2e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EMG49813.1 - 6.9e-14 51.8 8.8 1.5e-08 34.8 2.1 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG49813.1 - 9.4e-13 47.7 9.5 5.3e-09 35.7 3.3 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EMG49813.1 - 0.0053 17.1 15.2 1.2 10.0 0.5 4.9 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 EMG49813.1 - 0.063 12.8 0.4 0.18 11.3 0.4 1.7 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 EMG49813.1 - 0.1 12.7 7.8 0.23 11.6 0.3 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Not3 PF04065.15 EMG49814.1 - 7e-75 251.4 27.0 7e-75 251.4 27.0 2.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EMG49814.1 - 6.6e-37 126.5 4.3 6.6e-37 126.5 4.3 2.6 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family DUF1664 PF07889.12 EMG49814.1 - 0.72 9.9 10.6 0.15 12.1 0.8 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Orthopox_F8 PF05886.11 EMG49814.1 - 3.8 7.7 10.7 18 5.5 0.8 3.9 3 0 0 3 3 3 0 Orthopoxvirus F8 protein LMWPc PF01451.21 EMG49815.1 - 3.7e-39 134.3 0.0 4.3e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Opy2 PF09463.10 EMG49816.1 - 5.2e-10 39.5 21.9 8.3e-10 38.8 21.9 1.3 1 0 0 1 1 1 1 Opy2 protein Adeno_E3_CR2 PF02439.15 EMG49816.1 - 0.088 12.6 0.5 0.19 11.5 0.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 EMG49816.1 - 0.29 11.1 0.4 0.79 9.7 0.4 1.7 1 0 0 1 1 1 0 Syndecan domain TFIIA PF03153.13 EMG49816.1 - 4.5 7.2 31.9 3.7 7.5 28.5 1.9 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 EMG49816.1 - 6.5 7.8 12.0 12 6.9 3.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Enolase_C PF00113.22 EMG49817.1 - 8.2e-154 511.1 0.1 1.2e-153 510.6 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EMG49817.1 - 2.7e-56 189.3 0.0 5.7e-56 188.3 0.0 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EMG49817.1 - 7.8e-06 25.6 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EMG49817.1 - 0.0081 15.3 0.2 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Transketolase_N PF00456.21 EMG49818.1 - 3.5e-157 522.6 0.1 7.1e-157 521.6 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EMG49818.1 - 1.8e-45 154.8 0.0 3.1e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMG49818.1 - 9.9e-14 51.3 0.0 2.1e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 EMG49818.1 - 4.3e-07 29.2 0.1 1.8e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EMG49818.1 - 0.00075 19.3 0.5 0.011 15.5 0.2 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EMG49818.1 - 0.0022 17.2 0.0 0.0088 15.3 0.0 1.9 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Cas_Csd1 PF09709.10 EMG49818.1 - 0.18 10.5 0.1 0.31 9.7 0.0 1.4 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) Pkinase PF00069.25 EMG49819.1 - 2.9e-68 230.1 0.0 4.3e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49819.1 - 3.2e-30 105.3 0.0 4.6e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EMG49819.1 - 4.1e-12 46.6 1.8 4.1e-12 46.6 1.8 2.6 3 0 0 3 3 3 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EMG49819.1 - 0.00012 21.2 0.8 0.00012 21.2 0.8 2.2 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 EMG49819.1 - 0.00047 19.8 0.3 0.29 10.7 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EMG49819.1 - 0.0024 17.2 0.0 0.017 14.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EMG49819.1 - 0.093 12.1 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CdiI PF07262.11 EMG49819.1 - 0.14 11.9 0.3 1.1 9.0 0.3 2.2 1 1 0 1 1 1 0 CDI immunity protein NuA4 PF09340.10 EMG49821.1 - 2.5e-25 88.1 1.0 2.5e-25 88.1 1.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 FTA4 PF13093.6 EMG49821.1 - 0.0085 16.0 0.7 0.01 15.8 0.7 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2870 PF11069.8 EMG49821.1 - 0.088 13.2 1.2 0.26 11.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Nha1_C PF08619.10 EMG49821.1 - 0.33 10.1 13.9 1 8.5 13.9 1.7 1 1 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Secretin_N_2 PF07655.13 EMG49821.1 - 1.9 9.1 12.1 0.49 11.0 8.5 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain CBP4 PF07960.11 EMG49822.1 - 1e-53 180.6 1.7 1.2e-53 180.4 1.7 1.1 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 EMG49822.1 - 0.0025 17.7 0.1 0.0093 15.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF2098 PF09871.9 EMG49822.1 - 8.3 6.8 7.8 3.1 8.2 3.2 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2098) Clat_adaptor_s PF01217.20 EMG49823.1 - 3.9e-49 166.2 1.3 4.6e-49 166.0 1.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aminotran_5 PF00266.19 EMG49824.1 - 3.1e-08 33.0 0.0 5.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EMG49824.1 - 0.077 11.5 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RRF PF01765.19 EMG49824.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Na_Ca_ex PF01699.24 EMG49825.1 - 4.6e-45 153.3 35.8 1.2e-22 80.4 8.2 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PGPGW PF09656.10 EMG49825.1 - 0.87 9.2 8.0 3.2 7.4 0.2 3.9 3 0 0 3 3 3 0 Putative transmembrane protein (PGPGW) DUF2157 PF09925.9 EMG49825.1 - 1.4 8.7 11.5 0.081 12.7 1.7 3.0 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) 7tm_3 PF00003.22 EMG49825.1 - 2 8.1 24.6 0.13 11.9 4.8 3.7 1 1 3 4 4 4 0 7 transmembrane sweet-taste receptor of 3 GCPR Tad PF13400.6 EMG49825.1 - 7.5 6.9 7.2 12 6.3 0.3 4.2 3 1 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like Cyclin_N PF00134.23 EMG49826.1 - 2.5e-14 53.1 0.4 2.5e-14 53.1 0.4 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 EMG49826.1 - 1.3e-10 41.9 0.2 2.8e-10 40.8 0.2 1.6 1 0 0 1 1 1 1 Cyclin Cpn60_TCP1 PF00118.24 EMG49827.1 - 2.4e-154 514.6 17.5 2.7e-154 514.4 17.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HMG_box PF00505.19 EMG49828.1 - 0.009 16.4 9.3 0.053 13.9 2.2 4.1 3 2 1 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EMG49828.1 - 0.099 13.2 0.5 0.099 13.2 0.5 4.8 3 1 1 4 4 4 0 HMG-box domain DUF3106 PF11304.8 EMG49828.1 - 1.5 9.3 15.7 8.2 7.0 2.5 3.5 2 2 0 2 2 2 0 Protein of unknown function (DUF3106) SPT16 PF08644.11 EMG49828.1 - 1.8 8.8 9.7 0.27 11.4 4.2 1.9 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) Fungal_trans_2 PF11951.8 EMG49829.1 - 3.7e-11 42.5 0.3 5.8e-11 41.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG49829.1 - 6.1e-08 32.7 9.8 6.1e-08 32.7 9.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GDC-P PF02347.16 EMG49830.1 - 1.6e-194 646.7 0.0 1.6e-182 607.1 0.1 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EMG49830.1 - 2e-07 30.3 0.1 0.0035 16.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V S-methyl_trans PF02574.16 EMG49831.1 - 7.5e-62 209.6 0.0 8.5e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase PTA_PTB PF01515.19 EMG49831.1 - 0.032 13.5 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase MIF4G_like PF09088.11 EMG49832.1 - 6.8e-58 195.6 1.3 6.8e-58 195.6 1.3 2.2 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 EMG49832.1 - 2.9e-39 135.2 7.8 1.8e-35 122.7 1.9 3.7 3 1 1 4 4 4 2 MIF4G like MIF4G PF02854.19 EMG49832.1 - 0.0016 18.1 7.0 0.0028 17.3 1.5 3.6 4 0 0 4 4 4 1 MIF4G domain ABC_tran PF00005.27 EMG49833.1 - 2.8e-15 57.0 0.0 8.4e-15 55.5 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMG49833.1 - 3.6e-10 40.1 0.4 7.3e-05 22.7 0.3 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMG49833.1 - 6.1e-06 25.8 0.1 0.0014 18.1 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMG49833.1 - 0.00072 20.1 0.3 0.0013 19.3 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMG49833.1 - 0.0021 17.7 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EMG49833.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMG49833.1 - 0.012 16.1 0.0 0.032 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMG49833.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EMG49833.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 EMG49833.1 - 0.032 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMG49833.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 EMG49833.1 - 0.04 12.6 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMG49833.1 - 0.05 13.2 0.4 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EMG49833.1 - 0.064 13.2 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 EMG49833.1 - 0.08 13.4 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMG49833.1 - 0.096 13.0 0.0 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 EMG49835.1 - 2.4e-51 173.6 0.0 2.7e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG49835.1 - 1.3e-18 67.4 0.0 1.8e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG49835.1 - 1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.27 EMG49836.1 - 2.6e-09 37.7 0.0 2.9e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMG49836.1 - 0.041 13.3 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Flocculin_t3 PF13928.6 EMG49838.1 - 1.5e-11 44.6 23.2 1.5e-11 44.6 23.2 2.9 2 2 0 2 2 2 1 Flocculin type 3 repeat Cpn60_TCP1 PF00118.24 EMG49839.1 - 3.5e-142 474.5 10.1 4e-142 474.3 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EMG49839.1 - 0.18 11.3 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF2264 PF10022.9 EMG49839.1 - 0.25 10.4 0.0 0.39 9.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Dus PF01207.17 EMG49840.1 - 1.2e-73 247.9 0.0 1.6e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Mito_carr PF00153.27 EMG49840.1 - 5.1e-11 42.3 0.1 1.1e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial carrier protein PEMT PF04191.13 EMG49840.1 - 0.0078 16.6 1.0 0.24 11.8 0.1 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase Mito_carr PF00153.27 EMG49841.1 - 4.6e-62 206.0 6.7 1.6e-21 76.0 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EMG49841.1 - 1.8e-23 82.8 15.2 9.2e-12 45.2 3.3 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 EMG49841.1 - 1.3e-21 74.5 20.1 3.4e-05 23.1 0.5 5.4 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 EMG49841.1 - 2.6e-17 61.2 23.4 0.00044 20.0 0.1 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EMG49841.1 - 7e-15 54.6 9.8 6.4e-05 22.7 0.0 5.1 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 EMG49841.1 - 7.4e-11 41.0 16.4 0.00029 20.2 0.1 5.3 5 0 0 5 5 5 3 EF hand EF-hand_9 PF14658.6 EMG49841.1 - 8.3e-05 22.8 0.5 0.3 11.4 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EMG49841.1 - 0.00056 20.2 3.5 0.11 12.9 0.1 3.0 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Serine_protease PF18405.1 EMG49841.1 - 0.013 14.6 2.9 0.13 11.4 0.1 2.9 3 1 1 4 4 4 0 Gammaproteobacterial serine protease p25-alpha PF05517.12 EMG49841.1 - 0.03 14.5 3.5 12 6.0 0.3 3.4 1 1 2 3 3 3 0 p25-alpha EccE PF11203.8 EMG49841.1 - 0.045 14.1 0.2 0.15 12.4 0.5 1.6 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Dockerin_1 PF00404.18 EMG49841.1 - 0.051 13.8 4.2 12 6.2 0.2 3.5 1 1 3 4 4 4 0 Dockerin type I domain Colicin PF01024.19 EMG49841.1 - 0.097 12.6 0.6 0.2 11.5 0.6 1.5 1 0 0 1 1 1 0 Colicin pore forming domain DUF4734 PF15881.5 EMG49841.1 - 0.36 11.0 1.4 27 5.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4734) DUF866 PF05907.13 EMG49842.1 - 1.4e-56 190.7 2.8 1.6e-56 190.5 2.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF5319 PF17252.2 EMG49842.1 - 0.018 15.3 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5319) Zn-ribbon_8 PF09723.10 EMG49842.1 - 0.051 13.7 1.5 12 6.1 0.0 3.0 3 0 0 3 3 3 0 Zinc ribbon domain Cytochrom_c3_2 PF14537.6 EMG49842.1 - 0.2 12.2 2.7 2.5 8.6 3.2 2.0 1 1 1 2 2 2 0 Cytochrome c3 4HBT PF03061.22 EMG49843.1 - 2.5e-09 37.3 0.0 4.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Zn_clus PF00172.18 EMG49844.1 - 4.5e-06 26.7 10.9 7.9e-06 25.9 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rrp44_S1 PF17215.3 EMG49844.1 - 0.042 13.8 1.2 0.11 12.4 0.4 2.2 2 0 0 2 2 2 0 S1 domain Annexin PF00191.20 EMG49844.1 - 0.15 12.2 0.1 0.42 10.7 0.1 1.7 1 0 0 1 1 1 0 Annexin Opy2 PF09463.10 EMG49844.1 - 7.6 6.9 7.3 14 6.1 7.3 1.4 1 0 0 1 1 1 0 Opy2 protein Zn_clus PF00172.18 EMG49845.1 - 6.8e-08 32.5 11.4 1.1e-07 31.8 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Coatomer_WDAD PF04053.14 EMG49846.1 - 1.8e-135 452.5 9.4 2.9e-135 451.8 9.4 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EMG49846.1 - 2.4e-91 306.5 0.0 3.4e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EMG49846.1 - 1.4e-39 133.4 25.5 1.7e-09 38.2 1.3 8.7 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG49846.1 - 6e-09 36.1 0.8 0.016 15.5 0.0 5.8 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMG49846.1 - 3.1e-05 22.8 7.6 0.013 14.2 0.1 4.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EMG49846.1 - 0.12 12.3 1.3 1.9 8.3 0.0 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EMG49846.1 - 0.17 11.9 0.1 11 6.1 0.0 3.2 3 0 0 3 3 3 0 LisH MARVEL PF01284.23 EMG49847.1 - 0.00036 20.6 4.8 0.00073 19.6 4.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF716 PF04819.12 EMG49847.1 - 0.15 11.7 3.9 0.17 11.5 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF716) PLN_propep PF16485.5 EMG49847.1 - 0.28 10.9 3.0 0.16 11.7 0.4 2.0 2 1 0 2 2 2 0 Protealysin propeptide Cullin PF00888.22 EMG49848.1 - 6.4e-148 494.1 23.3 8.2e-148 493.8 23.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EMG49848.1 - 1.3e-21 76.4 0.9 5.2e-20 71.2 0.1 3.2 2 0 0 2 2 2 1 Cullin protein neddylation domain Castor1_N PF18700.1 EMG49848.1 - 0.094 12.6 0.3 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain RuvB_C PF05491.13 EMG49848.1 - 0.1 12.5 0.4 0.99 9.3 0.1 2.7 1 1 1 2 2 2 0 RuvB C-terminal winged helix domain DUF4327 PF14217.6 EMG49848.1 - 0.17 12.1 1.1 1.3 9.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4327) HTH_40 PF14493.6 EMG49848.1 - 0.28 11.7 0.1 0.28 11.7 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain ERp29 PF07749.12 EMG49848.1 - 0.42 11.6 5.7 0.21 12.5 0.7 3.2 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain Metallophos PF00149.28 EMG49849.1 - 3.5e-33 115.8 0.0 9.1e-33 114.5 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EMG49849.1 - 2.2e-27 95.2 0.3 4.3e-26 91.0 0.1 2.4 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 EMG49849.1 - 2.8e-17 61.7 8.6 1.8e-07 30.7 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMG49849.1 - 6.4e-13 48.1 1.8 1.7e-08 34.0 0.2 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.17 EMG49849.1 - 4.3e-12 45.2 6.5 7.9e-05 22.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMG49849.1 - 5.5e-10 38.9 0.9 0.00013 22.0 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMG49849.1 - 1.6e-07 30.9 2.4 0.035 14.3 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMG49849.1 - 2.6e-05 24.8 0.0 8.3e-05 23.2 0.0 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMG49849.1 - 5.9e-05 23.5 0.3 0.0002 21.8 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMG49849.1 - 0.0012 19.5 0.1 0.16 12.9 0.0 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMG49849.1 - 0.0074 16.6 1.4 4 7.8 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EMG49849.1 - 0.026 14.7 0.0 0.064 13.4 0.0 1.6 2 0 0 2 2 1 0 Tetratricopeptide repeat MIT PF04212.18 EMG49849.1 - 0.069 13.2 2.4 0.48 10.5 0.3 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 EMG49849.1 - 0.097 12.4 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 EMG49849.1 - 0.14 12.3 0.1 21 5.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMG49849.1 - 0.14 12.8 0.3 47 4.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Med7 PF05983.11 EMG49850.1 - 4.5e-66 222.6 2.0 5.9e-66 222.2 2.0 1.1 1 0 0 1 1 1 1 MED7 protein DUF1699 PF08004.11 EMG49850.1 - 0.062 13.0 3.1 0.14 11.9 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) ING PF12998.7 EMG49850.1 - 0.068 13.8 4.9 0.15 12.7 2.6 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding CBM_20 PF00686.19 EMG49850.1 - 0.18 11.7 0.9 8.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Starch binding domain Adaptin_N PF01602.20 EMG49851.1 - 3.3e-120 402.1 11.8 4.5e-120 401.7 11.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EMG49851.1 - 3.3e-62 209.3 1.3 3.3e-62 209.3 1.3 3.7 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMG49851.1 - 8.7e-11 42.1 0.0 2.4e-06 27.8 0.0 4.2 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 EMG49851.1 - 5.4e-09 35.6 0.5 0.23 11.8 0.0 5.5 6 0 0 6 6 6 3 HEAT repeat RTP1_C1 PF10363.9 EMG49851.1 - 0.043 14.0 0.1 10 6.4 0.0 3.6 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EMG49851.1 - 0.16 12.5 0.0 70 4.1 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat Metallophos PF00149.28 EMG49852.1 - 4.1e-32 112.3 0.2 6.3e-32 111.7 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WTX PF09422.10 EMG49852.1 - 0.022 13.9 4.7 0.032 13.3 4.7 1.1 1 0 0 1 1 1 0 WTX protein Presenilin PF01080.17 EMG49852.1 - 0.052 12.3 0.6 0.063 12.0 0.6 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 EMG49852.1 - 0.055 13.5 13.6 0.076 13.0 13.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EMG49852.1 - 0.056 12.1 0.1 0.065 11.9 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRN3 PF05327.11 EMG49852.1 - 0.47 8.9 6.9 0.62 8.5 6.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_U57 PF05582.12 EMG49852.1 - 0.48 9.6 2.6 0.72 9.1 2.6 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Spt20 PF12090.8 EMG49852.1 - 4.2 6.9 24.5 7 6.2 24.5 1.3 1 0 0 1 1 1 0 Spt20 family TRAP_alpha PF03896.16 EMG49852.1 - 5.1 6.2 6.7 7 5.8 6.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF702 PF05142.12 EMG49852.1 - 6.7 7.2 8.3 0.68 10.4 3.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF702) NAD_binding_10 PF13460.6 EMG49853.1 - 4e-14 52.9 0.0 6.7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMG49853.1 - 8.7e-14 51.6 0.1 3.7e-13 49.5 0.1 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EMG49853.1 - 7.8e-11 42.0 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EMG49853.1 - 3.1e-09 36.2 0.1 7.7e-09 34.9 0.1 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMG49853.1 - 1.2e-06 27.8 0.0 2.4e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 EMG49853.1 - 1.2e-05 25.6 0.0 2.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 EMG49853.1 - 0.0051 16.0 1.1 0.9 8.7 0.1 2.7 1 1 2 3 3 3 2 Male sterility protein DDE_Tnp_1_3 PF13612.6 EMG49853.1 - 0.045 13.8 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain OHCU_decarbox PF09349.10 EMG49854.1 - 1.4e-47 162.1 0.2 1.6e-47 161.9 0.2 1.0 1 0 0 1 1 1 1 OHCU decarboxylase ATP-synt_ab PF00006.25 EMG49855.1 - 3.9e-112 373.1 0.1 6e-112 372.5 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.16 EMG49855.1 - 3e-93 312.0 0.3 4.9e-93 311.3 0.3 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint ATP-synt_ab_Xtn PF16886.5 EMG49855.1 - 1e-44 151.3 0.0 2.6e-44 149.9 0.0 1.8 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension Hom_end PF05204.14 EMG49855.1 - 3.7e-39 133.3 3.2 3.4e-33 114.1 0.2 3.1 3 0 0 3 3 3 2 Homing endonuclease ATP-synt_ab_N PF02874.23 EMG49855.1 - 1.4e-15 57.5 2.9 4e-15 56.1 2.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.6 EMG49855.1 - 3.9e-07 30.3 0.0 0.0043 17.4 0.0 2.7 2 0 0 2 2 2 2 LAGLIDADG-like domain Hint_2 PF13403.6 EMG49855.1 - 0.0003 21.1 0.1 0.0014 18.9 0.1 2.1 1 1 0 1 1 1 1 Hint domain Hint PF01079.20 EMG49855.1 - 0.0021 17.6 0.0 0.0051 16.3 0.0 1.6 1 0 0 1 1 1 1 Hint module Mit_KHE1 PF10173.9 EMG49857.1 - 2.4e-52 177.8 0.5 2.4e-52 177.8 0.5 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related SKG6 PF08693.10 EMG49857.1 - 0.026 13.9 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MSV199 PF10553.9 EMG49857.1 - 0.76 10.0 5.1 0.93 9.7 0.6 2.2 2 0 0 2 2 2 0 MSV199 domain XhlA PF10779.9 EMG49858.1 - 0.37 11.0 0.5 0.37 11.0 0.5 1.6 2 0 0 2 2 2 0 Haemolysin XhlA Pam17 PF08566.10 EMG49859.1 - 1.3e-59 200.8 0.0 1.5e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.16 EMG49859.1 - 0.00083 18.6 0.7 0.0011 18.2 0.7 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component MFS_1 PF07690.16 EMG49859.1 - 0.011 14.7 0.9 0.014 14.4 0.9 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily SNF2_N PF00176.23 EMG49860.1 - 3.6e-72 243.0 0.7 9.9e-72 241.6 0.7 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMG49860.1 - 9.8e-23 80.6 0.1 1.5e-19 70.4 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Bromodomain PF00439.25 EMG49860.1 - 1.9e-18 66.3 0.1 6.4e-18 64.6 0.1 2.0 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 EMG49860.1 - 3.2e-14 53.3 0.2 3.2e-14 53.3 0.2 3.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SnAC PF14619.6 EMG49860.1 - 9.6e-09 35.7 4.1 9.6e-09 35.7 4.1 4.7 5 1 1 6 6 6 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 EMG49860.1 - 0.0016 18.7 13.4 0.0016 18.7 13.4 4.0 5 0 0 5 5 5 1 HSA peroxidase PF00141.23 EMG49861.1 - 7.7e-37 127.2 0.0 1.5e-36 126.3 0.0 1.5 1 0 0 1 1 1 1 Peroxidase GRIM-19 PF06212.12 EMG49861.1 - 0.0097 15.9 0.1 3.3 7.7 0.0 2.3 2 0 0 2 2 2 2 GRIM-19 protein Ribosomal_L6 PF00347.23 EMG49862.1 - 2.2e-29 101.9 8.9 5.7e-16 58.9 2.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.12 EMG49862.1 - 0.035 14.5 1.9 0.31 11.4 0.2 2.7 1 1 0 2 2 2 0 YbbR-like protein PDT PF00800.18 EMG49863.1 - 1.7e-63 213.8 0.1 2.1e-63 213.5 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EMG49863.1 - 1.6e-05 24.6 0.0 4.1e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 ACT domain Histone PF00125.24 EMG49864.1 - 8.8e-18 64.9 0.0 1e-17 64.7 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EMG49864.1 - 2.5e-06 27.6 0.0 3.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Coprogen_oxidas PF01218.18 EMG49865.1 - 1.2e-135 451.0 0.0 1.3e-135 450.9 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase UCR_hinge PF02320.16 EMG49866.1 - 9.2e-27 93.0 10.1 1.5e-26 92.3 10.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.13 EMG49866.1 - 0.049 13.5 9.8 0.065 13.1 9.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 EMG49866.1 - 1.4 7.2 6.9 1.4 7.1 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EMG49866.1 - 2.2 6.7 7.2 2.3 6.7 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 EMG49866.1 - 3.2 7.3 6.9 3.7 7.1 6.9 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF3295 PF11702.8 EMG49866.1 - 3.5 6.9 12.6 4.2 6.6 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Nop14 PF04147.12 EMG49866.1 - 7.2 4.7 13.7 8 4.5 13.7 1.0 1 0 0 1 1 1 0 Nop14-like family Actin PF00022.19 EMG49867.1 - 3.7e-11 42.3 0.1 3.9e-10 38.9 0.1 2.1 1 1 0 1 1 1 1 Actin Vps26 PF03643.15 EMG49868.1 - 5e-119 396.4 0.1 5.8e-119 396.1 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EMG49868.1 - 3.8e-06 27.0 5.5 0.00051 20.1 1.1 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain MG2 PF01835.19 EMG49868.1 - 0.029 14.8 0.3 0.17 12.3 0.0 2.4 2 1 0 2 2 2 0 MG2 domain RasGEF PF00617.19 EMG49869.1 - 1.9e-56 191.1 2.5 3.2e-56 190.3 0.8 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EMG49869.1 - 6.3e-25 87.4 1.0 3.1e-24 85.2 0.2 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 EMG49869.1 - 6.1e-17 61.0 0.0 1.5e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMG49869.1 - 5.3e-10 39.0 0.1 5.2e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EMG49869.1 - 4.5e-08 32.6 0.0 2.8e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain Zn_clus PF00172.18 EMG49870.1 - 0.00013 22.0 7.2 0.00027 21.0 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC5 PF12862.7 EMG49870.1 - 0.073 13.1 1.1 0.31 11.1 1.1 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 SPX PF03105.19 EMG49870.1 - 0.17 11.8 17.6 0.29 11.0 17.6 1.3 1 0 0 1 1 1 0 SPX domain SNF2_N PF00176.23 EMG49871.1 - 1e-45 156.0 0.0 2.6e-45 154.7 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Peptidase_M41 PF01434.18 EMG49872.1 - 4.8e-66 222.3 0.2 7.7e-66 221.6 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EMG49872.1 - 9.9e-42 142.5 0.0 2.3e-41 141.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMG49872.1 - 1e-08 34.9 1.3 1.5e-08 34.3 0.2 2.0 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 EMG49872.1 - 7.3e-05 23.1 0.3 0.00038 20.8 0.2 2.2 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.6 EMG49872.1 - 0.002 18.4 0.7 0.72 10.1 0.1 2.8 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 EMG49872.1 - 0.0029 16.9 0.7 0.0093 15.2 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 EMG49872.1 - 0.0053 16.5 0.0 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EMG49872.1 - 0.015 15.3 0.9 0.056 13.4 0.1 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMG49872.1 - 0.016 15.6 0.1 0.065 13.6 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EMG49872.1 - 0.03 14.0 0.1 0.097 12.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.6 EMG49872.1 - 0.054 13.9 2.1 0.089 13.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EMG49872.1 - 0.06 13.5 0.0 0.06 13.5 0.0 2.8 4 0 0 4 4 4 0 AAA domain (Cdc48 subfamily) AAA_11 PF13086.6 EMG49872.1 - 0.31 10.8 8.3 7.4 6.3 0.1 2.7 3 0 0 3 3 3 0 AAA domain Hid1 PF12722.7 EMG49872.1 - 3 5.9 4.5 4.4 5.3 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NYD-SP28 PF14772.6 EMG49872.1 - 3.6 7.7 14.7 0.31 11.1 0.9 2.5 2 0 0 2 2 2 0 Sperm tail Glyco_transf_15 PF01793.16 EMG49874.1 - 9.1e-132 439.2 12.7 1.1e-131 438.9 12.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DAPDH_C PF16654.5 EMG49874.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Glyco_hydro_3_C PF01915.22 EMG49875.1 - 8.3e-60 202.2 0.0 2.7e-59 200.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMG49875.1 - 4.1e-46 157.8 0.0 6.8e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMG49875.1 - 5.4e-25 87.3 1.3 6.4e-24 83.9 2.2 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 EMG49875.1 - 3.7e-17 62.5 0.5 6.7e-17 61.7 0.5 1.4 1 0 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.6 EMG49875.1 - 0.031 14.7 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Glyco_transf_15 PF01793.16 EMG49876.1 - 1.1e-135 452.1 17.6 1.5e-135 451.6 17.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF3437 PF11919.8 EMG49876.1 - 0.022 14.7 1.5 0.38 10.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Peptidase_C37 PF05416.12 EMG49876.1 - 0.046 12.2 0.5 0.061 11.8 0.5 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Glyco_hydro_15 PF00723.21 EMG49877.1 - 4e-49 167.6 0.0 5.3e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Sec7 PF01369.20 EMG49878.1 - 2.1e-66 223.1 0.4 5.7e-66 221.7 0.4 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EMG49878.1 - 1.5e-12 47.7 6.9 1.8e-12 47.5 1.8 3.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal MID_MedPIWI PF18296.1 EMG49878.1 - 0.32 10.7 6.8 0.12 12.2 1.6 2.8 3 0 0 3 3 3 0 MID domain of medPIWI PHB_depo_C PF06850.11 EMG49879.1 - 0.063 12.7 0.1 0.082 12.3 0.1 1.2 1 0 0 1 1 1 0 PHB de-polymerase C-terminus DUF2401 PF10287.9 EMG49880.1 - 8.9e-90 300.3 0.2 1.8e-89 299.3 0.2 1.5 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EMG49880.1 - 2.1e-28 98.5 0.2 5.4e-28 97.2 0.2 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) CHCH PF06747.13 EMG49881.1 - 3.4e-06 27.0 4.6 6.3e-06 26.2 4.6 1.5 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EMG49881.1 - 0.066 13.2 4.1 0.57 10.2 0.4 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, PutA_N PF18083.1 EMG49881.1 - 0.09 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Proline utilization A N-terminal domain Glyco_hydro_16 PF00722.21 EMG49882.1 - 3.2e-45 153.8 9.1 8.1e-45 152.4 9.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EMG49882.1 - 0.0037 17.7 12.7 0.0069 16.8 12.7 1.4 1 0 0 1 1 1 1 Chitin recognition protein Nodulin_late PF07127.11 EMG49882.1 - 0.54 10.6 2.0 1 9.8 2.0 1.3 1 0 0 1 1 1 0 Late nodulin protein BRO1 PF03097.18 EMG49884.1 - 1.7e-121 405.7 6.2 1.7e-121 405.7 6.2 2.5 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EMG49884.1 - 5.8e-21 75.1 15.1 3.3e-20 72.6 14.8 2.2 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV DUF3958 PF13125.6 EMG49884.1 - 0.99 9.6 0.0 0.99 9.6 0.0 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF3958) ENT PF03735.14 EMG49884.1 - 1.1 9.3 4.9 20 5.3 0.0 3.9 4 0 0 4 4 4 0 ENT domain OMPdecase PF00215.24 EMG49885.1 - 6.2e-78 261.5 0.0 7e-78 261.3 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Mito_carr PF00153.27 EMG49886.1 - 5.1e-14 52.0 1.2 8.1e-08 32.1 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Cadherin-like PF12733.7 EMG49888.1 - 0.033 14.7 7.8 0.92 10.1 0.7 2.2 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain Ribosomal_L6 PF00347.23 EMG49888.1 - 0.05 14.3 2.9 6.6 7.5 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein L6 DUF374 PF04028.13 EMG49888.1 - 0.22 11.1 0.8 3 7.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF374) STE3 PF02076.15 EMG49889.1 - 0.00032 20.0 0.8 0.00044 19.6 0.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4234 PF14018.6 EMG49889.1 - 0.011 15.9 1.1 0.011 15.9 1.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) Trep_Strep PF09605.10 EMG49889.1 - 0.013 15.5 0.3 0.013 15.5 0.3 1.6 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4064 PF13273.6 EMG49889.1 - 0.014 15.7 5.4 0.056 13.7 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) EamA PF00892.20 EMG49889.1 - 0.018 15.2 0.2 0.018 15.2 0.2 2.7 2 1 0 2 2 2 0 EamA-like transporter family DUF1980 PF09323.10 EMG49889.1 - 0.23 11.3 1.8 0.35 10.8 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Rav1p_C PF12234.8 EMG49890.1 - 3.4e-240 798.8 11.6 2.8e-239 795.8 7.2 2.4 2 1 0 2 2 2 2 RAVE protein 1 C terminal HPS3_N PF14761.6 EMG49890.1 - 0.021 14.3 0.0 1.7 8.1 0.0 2.6 1 1 1 2 2 2 0 Hermansky-Pudlak syndrome 3 Cation_ATPase_C PF00689.21 EMG49891.1 - 1.8e-45 154.9 7.2 1.8e-45 154.9 7.2 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EMG49891.1 - 3.5e-39 134.2 0.6 3.5e-39 134.2 0.6 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 EMG49891.1 - 5.1e-25 87.4 0.0 1e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMG49891.1 - 1.1e-16 61.8 0.2 1.8e-15 57.8 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMG49891.1 - 1.5e-11 43.8 0.0 4e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMG49891.1 - 0.00033 20.5 1.4 0.0018 18.0 0.1 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase SNF2_N PF00176.23 EMG49892.1 - 2.5e-67 227.1 2.0 3.3e-67 226.7 1.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMG49892.1 - 7.6e-22 77.8 1.5 9.1e-21 74.3 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG49892.1 - 7.8e-10 39.0 0.0 7.8e-10 39.0 0.0 3.4 3 2 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMG49892.1 - 4.2e-06 26.6 0.2 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EMG49892.1 - 5e-06 25.9 0.7 1.6e-05 24.3 0.7 1.8 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Pro_CA PF00484.19 EMG49893.1 - 3e-42 144.6 0.0 3.8e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Lysine_decarbox PF03641.14 EMG49894.1 - 5.6e-38 130.0 0.0 6.9e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EMG49894.1 - 2.4e-12 46.7 0.3 4.4e-12 45.9 0.3 1.6 1 1 0 1 1 1 1 SLOG cluster4 family Hema_HEFG PF02710.14 EMG49894.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.5 2 0 0 2 2 2 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein Cu_amine_oxidN1 PF07833.11 EMG49895.1 - 0.25 11.9 9.0 6 7.4 0.5 3.5 1 1 1 3 3 3 0 Copper amine oxidase N-terminal domain Aldo_ket_red PF00248.21 EMG49897.1 - 3.5e-39 134.8 0.2 1.4e-37 129.5 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GntR PF00392.21 EMG49897.1 - 0.008 15.8 0.0 0.59 9.8 0.0 2.7 2 0 0 2 2 2 2 Bacterial regulatory proteins, gntR family Maf1 PF09174.10 EMG49898.1 - 3.2e-32 112.1 8.6 1.8e-23 83.5 0.8 3.0 2 1 0 2 2 2 2 Maf1 regulator UPF0147 PF03685.13 EMG49898.1 - 0.026 14.6 0.2 0.059 13.4 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) NOA36 PF06524.12 EMG49898.1 - 4.3 6.6 6.1 6.7 5.9 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein Rad51 PF08423.11 EMG49899.1 - 1.2e-23 83.7 0.6 6.8e-23 81.2 0.0 2.4 3 0 0 3 3 3 1 Rad51 ATPase PF06745.13 EMG49899.1 - 1.6e-06 27.7 3.7 0.00044 19.7 1.1 3.1 1 1 0 2 2 2 2 KaiC RecA PF00154.21 EMG49899.1 - 2.5e-05 23.9 0.0 6.7e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ABC_tran PF00005.27 EMG49899.1 - 0.00066 20.2 0.1 0.0017 18.9 0.1 1.8 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 EMG49899.1 - 0.0022 17.9 0.3 0.0044 17.0 0.3 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_25 PF13481.6 EMG49899.1 - 0.0023 17.5 0.0 0.16 11.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain FlgT_M PF16539.5 EMG49899.1 - 0.0053 16.9 0.9 0.012 15.8 0.7 1.7 1 1 0 1 1 1 1 Flagellar assembly protein T, middle domain NACHT PF05729.12 EMG49899.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EMG49899.1 - 0.014 15.2 0.0 0.026 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EMG49899.1 - 0.02 15.2 0.4 0.067 13.5 0.4 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMG49899.1 - 0.052 13.9 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EMG49899.1 - 0.057 13.5 0.7 1.4 9.0 0.6 2.7 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 EMG49899.1 - 0.074 12.4 1.1 1.1 8.6 1.1 2.6 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain LRR_4 PF12799.7 EMG49900.1 - 2e-07 31.2 31.3 0.0066 16.9 0.9 10.2 10 2 2 12 12 12 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG49900.1 - 6.8e-06 25.8 15.0 0.0074 16.0 0.8 6.2 5 2 1 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 EMG49900.1 - 0.00074 19.7 10.6 5.8 7.9 0.8 7.8 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 EMG49900.1 - 0.58 10.4 5.1 82 3.6 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich repeat Fungal_trans PF04082.18 EMG49901.1 - 3.8e-06 26.1 0.5 7.1e-06 25.2 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyridoxal_deC PF00282.19 EMG49902.1 - 1.2e-72 244.7 0.0 1.6e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EMG49902.1 - 1.3e-07 31.2 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EMG49902.1 - 0.00011 21.3 0.0 0.00025 20.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V MFS_1 PF07690.16 EMG49903.1 - 4.2e-16 58.8 34.2 6.5e-16 58.2 34.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMG49903.1 - 2.2e-12 47.0 11.7 3.2e-11 43.2 9.1 3.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DNA_ligase_A_N PF04675.14 EMG49903.1 - 0.05 13.9 0.6 0.091 13.1 0.6 1.5 1 0 0 1 1 1 0 DNA ligase N terminus p25-alpha PF05517.12 EMG49903.1 - 0.2 11.8 2.2 0.44 10.7 2.2 1.5 1 0 0 1 1 1 0 p25-alpha LOH1CR12 PF10158.9 EMG49903.1 - 0.32 11.0 4.7 0.51 10.4 2.2 2.3 1 1 1 2 2 2 0 Tumour suppressor protein FlaC_arch PF05377.11 EMG49903.1 - 1.4 9.4 16.1 0.19 12.1 6.1 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TBCC_N PF16752.5 EMG49903.1 - 4.5 7.8 12.1 2.7 8.5 2.3 3.0 1 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain ABC_tran PF00005.27 EMG49904.1 - 1.4e-47 161.6 0.4 2.7e-22 79.8 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EMG49904.1 - 3e-22 78.4 0.4 3e-22 78.4 0.4 3.3 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.6 EMG49904.1 - 4.2e-18 66.2 0.5 3.3e-05 23.8 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMG49904.1 - 1.8e-10 40.7 0.7 0.026 14.0 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMG49904.1 - 7.9e-08 31.9 0.0 0.003 17.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EMG49904.1 - 2.6e-07 31.2 0.0 0.0019 18.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EMG49904.1 - 1.2e-05 25.2 0.2 0.14 12.1 0.0 2.8 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 EMG49904.1 - 1.3e-05 25.2 0.5 0.034 14.1 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EMG49904.1 - 1.4e-05 25.3 0.0 0.14 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EMG49904.1 - 4.4e-05 23.8 0.0 0.21 12.0 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_23 PF13476.6 EMG49904.1 - 4.8e-05 24.0 18.5 0.11 13.0 0.0 4.3 4 0 0 4 4 3 2 AAA domain NB-ARC PF00931.22 EMG49904.1 - 6.7e-05 22.2 0.0 0.82 8.8 0.0 3.3 3 0 0 3 3 3 2 NB-ARC domain AAA_24 PF13479.6 EMG49904.1 - 0.00013 21.8 0.1 0.16 11.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 EMG49904.1 - 0.00013 22.0 0.0 0.63 10.0 0.1 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EMG49904.1 - 0.00016 22.0 1.1 0.19 12.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 EMG49904.1 - 0.00019 21.9 0.0 0.22 12.0 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EMG49904.1 - 0.00031 20.8 0.0 0.52 10.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 EMG49904.1 - 0.00058 19.7 12.8 0.003 17.3 0.0 3.7 3 1 1 4 4 4 2 AAA ATPase domain MCM PF00493.23 EMG49904.1 - 0.0013 17.9 0.0 0.56 9.3 0.0 2.7 2 0 0 2 2 2 1 MCM P-loop domain MMR_HSR1 PF01926.23 EMG49904.1 - 0.0014 18.7 0.0 3.3 7.8 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EMG49904.1 - 0.0017 18.1 0.1 0.53 10.0 0.0 3.5 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 EMG49904.1 - 0.002 18.3 0.0 3.5 7.9 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EMG49904.1 - 0.0031 17.7 0.7 3.2 7.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 EMG49904.1 - 0.0034 16.9 0.0 1.9 8.0 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region G-alpha PF00503.20 EMG49904.1 - 0.0047 16.1 0.4 5.3 6.1 0.0 3.3 3 1 1 4 4 4 0 G-protein alpha subunit TsaE PF02367.17 EMG49904.1 - 0.0047 16.9 0.4 27 4.8 0.0 3.6 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DLIC PF05783.11 EMG49904.1 - 0.0069 15.3 0.0 0.18 10.6 0.0 2.4 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_18 PF13238.6 EMG49904.1 - 0.012 16.1 0.0 10 6.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EMG49904.1 - 0.027 14.4 0.0 7 6.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Mrr_cat PF04471.12 EMG49904.1 - 0.034 14.2 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 1 0 Restriction endonuclease DUF815 PF05673.13 EMG49904.1 - 0.035 13.3 2.9 5.3 6.1 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EMG49904.1 - 0.036 14.0 7.1 0.8 9.6 0.0 3.6 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea PRK PF00485.18 EMG49904.1 - 0.044 13.5 0.1 5.9 6.6 0.0 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.21 EMG49904.1 - 0.045 13.1 0.0 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EMG49904.1 - 0.045 13.3 0.0 6.5 6.3 0.0 3.4 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.9 EMG49904.1 - 0.051 13.3 0.4 10 5.9 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 EMG49904.1 - 0.064 13.2 0.1 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 NTPase NARP1 PF12569.8 EMG49904.1 - 0.52 9.1 7.8 0.86 8.4 7.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_27 PF13514.6 EMG49904.1 - 0.9 9.1 10.4 1.3 8.5 0.0 3.7 4 0 0 4 4 2 0 AAA domain DUF2813 PF11398.8 EMG49904.1 - 1.3 8.2 4.5 9.4 5.4 0.0 2.9 4 0 0 4 4 2 0 Protein of unknown function (DUF2813) Ureide_permease PF07168.11 EMG49904.1 - 4.7 5.9 6.1 6.7 5.4 3.1 2.0 2 0 0 2 2 2 0 Ureide permease DUF87 PF01935.17 EMG49904.1 - 6.6 6.7 10.0 3.6 7.6 0.0 3.8 4 1 1 5 5 3 0 Helicase HerA, central domain BLM10_mid PF16507.5 EMG49905.1 - 5.4e-188 625.9 4.2 1.3e-187 624.6 4.2 1.7 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 EMG49905.1 - 2.6e-30 104.5 0.1 8.3e-30 102.9 0.1 2.0 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal DUF3437 PF11919.8 EMG49905.1 - 2.3e-25 88.3 0.0 1.2e-24 86.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) MINDY_DUB PF04424.13 EMG49905.1 - 0.082 12.9 0.6 13 5.9 0.1 3.2 2 0 0 2 2 2 0 MINDY deubiquitinase CBM64 PF18666.1 EMG49905.1 - 0.17 12.0 0.4 0.51 10.5 0.4 1.8 1 0 0 1 1 1 0 Carbohydrate-binding module 64 SURF2 PF05477.11 EMG49905.1 - 0.64 9.7 3.8 1.5 8.4 3.8 1.6 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) EF-hand_1 PF00036.32 EMG49906.1 - 2.9e-13 48.3 2.8 0.00047 19.5 0.0 4.4 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 EMG49906.1 - 6.5e-13 47.5 1.6 9.5e-05 21.7 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EMG49906.1 - 5e-11 41.6 9.7 0.00049 19.8 0.0 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 EMG49906.1 - 3.3e-09 37.1 6.9 0.0022 18.4 0.2 3.4 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EMG49906.1 - 7.2e-05 22.6 2.7 0.13 12.1 0.0 3.8 4 1 0 4 4 4 2 EF-hand domain pair S10_plectin PF03501.15 EMG49907.1 - 4.1e-37 126.1 0.1 4.7e-37 125.9 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF4364 PF14277.6 EMG49907.1 - 0.032 14.0 0.1 0.062 13.0 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Replic_Relax PF13814.6 EMG49907.1 - 0.09 12.8 0.0 0.092 12.8 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation MFS_1 PF07690.16 EMG49908.1 - 3.6e-07 29.4 53.8 1.1e-06 27.9 52.3 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG49908.1 - 0.0011 18.0 39.7 0.0015 17.5 14.4 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter Pam17 PF08566.10 EMG49908.1 - 0.15 11.9 0.6 0.5 10.2 0.6 1.9 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Mito_carr PF00153.27 EMG49909.1 - 9.1e-63 208.2 2.5 2.8e-22 78.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMG49909.1 - 0.022 13.9 0.3 1.6 7.8 0.1 2.6 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Peptidase_M1 PF01433.20 EMG49910.1 - 3.3e-72 242.6 0.0 5.6e-72 241.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EMG49910.1 - 1e-56 192.8 0.2 1.6e-56 192.2 0.2 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EMG49910.1 - 2.1e-53 181.3 0.5 7.2e-52 176.3 0.4 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 EMG49910.1 - 0.035 13.5 0.1 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative aminopeptidase Pribosyl_synth PF14572.6 EMG49912.1 - 8.1e-40 136.8 1.9 1.4e-39 136.0 1.9 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EMG49912.1 - 3.3e-32 110.8 0.0 1.1e-31 109.1 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EMG49912.1 - 6.2e-14 51.8 0.1 1.4e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMG49912.1 - 0.065 12.7 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ELFV_dehydrog PF00208.21 EMG49914.1 - 7.8e-67 225.5 0.0 1.2e-66 224.9 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EMG49914.1 - 5.9e-20 70.5 0.0 3.4e-15 54.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EMG49914.1 - 0.0038 17.1 0.0 0.16 11.8 0.0 3.1 3 0 0 3 3 3 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NPHI_C PF08469.10 EMG49914.1 - 0.38 10.7 3.9 0.61 10.1 0.2 2.9 3 0 0 3 3 3 0 Nucleoside triphosphatase I C-terminal WH2 PF02205.20 EMG49916.1 - 6.8e-14 51.2 0.0 2.2e-10 40.0 0.1 2.9 2 0 0 2 2 2 2 WH2 motif Asn_synthase PF00733.21 EMG49919.1 - 9.2e-22 78.2 0.1 1.3e-14 54.6 0.1 3.3 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EMG49919.1 - 4.3e-10 39.6 0.0 1.7e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EMG49919.1 - 0.00022 21.4 0.0 0.0016 18.6 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain FlxA PF14282.6 EMG49919.1 - 0.14 12.2 5.1 0.31 11.1 5.1 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF2533 PF10752.9 EMG49919.1 - 0.23 11.9 1.1 1.4 9.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) PHD PF00628.29 EMG49920.1 - 0.0011 18.8 6.8 0.0027 17.6 6.8 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EMG49920.1 - 0.026 14.8 4.9 0.075 13.3 4.9 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain RNA_pol_Rpb2_3 PF04565.16 EMG49920.1 - 0.13 12.5 0.2 0.29 11.3 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 Late_protein_L2 PF00513.18 EMG49920.1 - 0.87 8.5 4.9 1.3 8.0 4.9 1.2 1 0 0 1 1 1 0 Late Protein L2 Presenilin PF01080.17 EMG49920.1 - 5.3 5.7 5.3 6.6 5.4 5.3 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EMG49921.1 - 5.6e-55 186.9 13.1 2.6e-54 184.7 13.1 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF805 PF05656.14 EMG49921.1 - 0.11 12.9 1.4 0.61 10.5 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Zip PF02535.22 EMG49922.1 - 8.7e-34 117.2 0.4 1e-33 117.0 0.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3464 PF11947.8 EMG49922.1 - 0.067 12.9 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4728 PF15860.5 EMG49922.1 - 0.79 10.4 3.7 0.94 10.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4728) RNB PF00773.19 EMG49923.1 - 1.4e-53 182.4 3.8 1.4e-53 182.4 3.8 2.7 2 1 0 2 2 2 1 RNB domain Peptidase_M15_4 PF13539.6 EMG49923.1 - 0.16 12.5 0.1 9.3 6.8 0.0 3.0 3 0 0 3 3 3 0 D-alanyl-D-alanine carboxypeptidase FAA_hydrolase PF01557.18 EMG49924.1 - 1.6e-60 204.5 0.0 2.1e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family NAD_binding_6 PF08030.12 EMG49927.1 - 1.8e-26 93.1 0.2 2.8e-26 92.5 0.2 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EMG49927.1 - 3.8e-25 88.4 20.2 1.3e-24 86.7 18.1 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EMG49927.1 - 1.3e-24 86.3 0.0 2.8e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain CFEM PF05730.11 EMG49927.1 - 0.023 14.8 3.5 0.051 13.7 3.5 1.5 1 0 0 1 1 1 0 CFEM domain MARVEL PF01284.23 EMG49927.1 - 7.3 6.6 14.5 4.6 7.3 8.8 2.9 2 1 1 3 3 3 0 Membrane-associating domain Methyltransf_31 PF13847.6 EMG49928.1 - 0.0084 15.9 0.1 0.01 15.7 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain LRR_8 PF13855.6 EMG49929.1 - 2.1e-05 24.2 11.7 0.0014 18.3 0.5 5.0 5 0 0 5 5 5 2 Leucine rich repeat F-box-like PF12937.7 EMG49929.1 - 0.012 15.5 0.4 0.035 14.0 0.4 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EMG49929.1 - 0.073 13.0 0.2 0.25 11.3 0.2 2.0 1 0 0 1 1 1 0 F-box domain FNIP PF05725.12 EMG49929.1 - 1.3 9.3 19.5 1.3 9.3 0.5 7.2 8 0 0 8 8 8 0 FNIP Repeat MCM PF00493.23 EMG49930.1 - 4.4e-102 339.9 0.0 6.7e-102 339.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMG49930.1 - 2.7e-30 104.8 0.1 4.7e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EMG49930.1 - 2.4e-21 75.9 0.4 7.4e-21 74.4 0.1 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EMG49930.1 - 2.7e-15 56.8 1.6 7.5e-15 55.4 1.6 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMG49930.1 - 1.1e-07 31.4 0.1 2e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMG49930.1 - 1.3e-07 31.7 0.0 2.1e-06 27.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EMG49930.1 - 0.009 15.9 0.0 0.026 14.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Phage_int_SAM_4 PF13495.6 EMG49930.1 - 0.02 15.4 0.1 0.69 10.4 0.1 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Sigma54_activat PF00158.26 EMG49930.1 - 0.13 12.0 0.0 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Stb3 PF10330.9 EMG49931.1 - 1.3e-29 102.1 0.0 3.2e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Putative Sin3 binding protein RCR PF12273.8 EMG49934.1 - 0.0024 18.5 2.8 0.0055 17.4 2.8 1.7 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Acyltransferase PF01553.21 EMG49935.1 - 7.6e-14 51.5 0.0 1.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Asn_synthase PF00733.21 EMG49936.1 - 5.1e-95 319.1 0.1 7.7e-54 183.7 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EMG49936.1 - 9.8e-35 119.1 0.0 1.7e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EMG49936.1 - 2.3e-28 99.1 0.0 4.1e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EMG49936.1 - 9.3e-06 25.3 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EMG49936.1 - 0.17 11.0 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Pmp3 PF01679.17 EMG49937.1 - 2e-18 66.3 6.2 2.9e-18 65.8 6.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SelP_N PF04592.14 EMG49937.1 - 9 5.6 14.8 11 5.3 14.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Abhydrolase_1 PF00561.20 EMG49938.1 - 1.5e-15 57.6 0.0 2.6e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG49938.1 - 9.5e-10 38.1 0.0 3.5e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMG49938.1 - 2.3e-07 31.6 0.0 3.9e-07 30.9 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 EMG49938.1 - 9.9e-05 21.8 0.2 0.0002 20.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 EMG49938.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 EMG49938.1 - 0.0064 15.4 0.0 0.0099 14.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 EMG49938.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase LIDHydrolase PF10230.9 EMG49938.1 - 0.017 14.7 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 EMG49938.1 - 0.037 13.9 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4809 PF16067.5 EMG49938.1 - 0.076 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4809) Phage_holin_2_2 PF10746.9 EMG49938.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II Thioesterase PF00975.20 EMG49938.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain MutS_V PF00488.21 EMG49939.1 - 4.2e-66 222.6 0.5 3.7e-65 219.5 0.1 2.5 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EMG49939.1 - 1.7e-28 100.1 3.4 2.3e-28 99.7 2.2 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EMG49939.1 - 1.7e-22 79.8 0.1 5.9e-22 78.0 0.1 2.0 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EMG49939.1 - 1.2e-09 38.5 1.7 2.4e-09 37.6 0.1 2.4 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EMG49939.1 - 2.2e-07 31.1 3.8 1.1e-06 28.9 3.8 2.2 1 0 0 1 1 1 1 MutS family domain IV ssDNA_DBD PF18333.1 EMG49939.1 - 0.94 9.6 9.5 4.6 7.4 0.6 3.4 3 0 0 3 3 3 0 Non-canonical single-stranded DNA-binding domain ATP-sulfurylase PF01747.17 EMG49940.1 - 4.7e-82 274.6 0.0 6.8e-82 274.0 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EMG49940.1 - 6.7e-51 172.1 0.0 1.1e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain CTP_transf_like PF01467.26 EMG49940.1 - 0.071 13.3 0.0 0.21 11.8 0.0 1.8 1 1 0 1 1 1 0 Cytidylyltransferase-like zf-C2H2 PF00096.26 EMG49941.1 - 1.4e-07 31.5 8.9 0.0018 18.6 1.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMG49941.1 - 8.9e-07 29.1 5.9 3.5e-05 24.0 3.5 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMG49941.1 - 0.00056 20.5 9.2 0.086 13.7 1.5 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EMG49941.1 - 0.59 9.9 6.1 0.12 12.2 0.6 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type MFS_1 PF07690.16 EMG49942.1 - 1e-28 100.3 27.0 1e-28 100.3 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DctQ PF04290.12 EMG49942.1 - 0.0036 17.2 6.6 0.0093 15.9 0.4 3.5 3 1 0 3 3 3 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF5316 PF17247.2 EMG49942.1 - 0.086 12.9 1.9 3.1 7.9 0.6 3.3 2 0 0 2 2 2 0 Family of unknown function (DUF5316) JAB PF01398.21 EMG49943.1 - 3.6e-06 27.0 1.0 2.9e-05 24.0 0.1 2.6 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TssD PF17642.1 EMG49943.1 - 0.074 12.9 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Hemolysin coregulated protein Hcp (TssD) 6PGD PF00393.19 EMG49944.1 - 2.6e-126 420.9 0.0 3.3e-126 420.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EMG49944.1 - 2.7e-52 177.1 0.0 4e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMG49944.1 - 0.0017 18.9 0.1 0.0034 17.9 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMG49944.1 - 0.0051 16.9 0.3 0.017 15.2 0.1 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EMG49944.1 - 0.024 14.0 0.0 0.059 12.7 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EMG49944.1 - 0.071 12.8 0.1 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.6 EMG49944.1 - 0.081 13.2 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 EMG49944.1 - 0.11 12.4 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SSF PF00474.17 EMG49945.1 - 1.4e-22 80.1 13.8 2.2e-22 79.5 13.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Biotin_lipoyl PF00364.22 EMG49946.1 - 3.5e-20 71.6 0.5 7e-20 70.6 0.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EMG49946.1 - 7.8e-10 38.9 0.0 1.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EMG49946.1 - 0.0094 15.8 0.0 1.5 8.7 0.0 3.2 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.6 EMG49946.1 - 0.094 13.4 0.5 3 8.6 0.0 3.0 2 1 1 3 3 3 0 HlyD family secretion protein Nramp PF01566.18 EMG49947.1 - 1.8e-89 300.2 6.6 3.1e-49 167.9 5.5 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein SSF PF00474.17 EMG49948.1 - 2.5e-25 89.2 26.7 4.2e-25 88.5 26.7 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family TFIIA PF03153.13 EMG49950.1 - 0.00031 20.9 46.5 0.00045 20.3 46.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AT_hook PF02178.19 EMG49950.1 - 0.23 11.5 13.5 0.4 10.7 3.1 2.6 2 0 0 2 2 2 0 AT hook motif GREB1 PF15782.5 EMG49950.1 - 6.5 3.7 26.5 9 3.3 26.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SSF PF00474.17 EMG49951.1 - 3.2e-25 88.9 24.3 4.2e-25 88.5 24.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Response_reg PF00072.24 EMG49952.1 - 4e-19 68.8 0.0 3e-13 49.9 0.0 2.4 1 1 1 2 2 2 2 Response regulator receiver domain BSP_II PF05432.11 EMG49952.1 - 0.00063 19.5 14.8 0.0013 18.5 14.8 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF5024 PF16427.5 EMG49952.1 - 0.0015 18.9 0.0 0.005 17.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5024) TFIIA PF03153.13 EMG49952.1 - 0.062 13.3 21.6 0.015 15.3 14.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUN PF03856.13 EMG49954.1 - 6.1e-93 310.8 17.7 7.7e-93 310.4 17.7 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Ldh_1_C PF02866.18 EMG49954.1 - 0.15 12.0 0.6 0.51 10.3 0.0 2.1 3 0 0 3 3 3 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain zf-MYND PF01753.18 EMG49954.1 - 0.16 12.1 2.1 0.37 10.9 2.1 1.5 1 0 0 1 1 1 0 MYND finger Kinetochor_Ybp2 PF08568.10 EMG49955.1 - 7.3e-153 510.4 21.9 9e-153 510.1 21.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin AKAP_110 PF05716.13 EMG49955.1 - 0.096 10.9 0.6 0.18 10.0 0.6 1.4 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) HUN PF08729.10 EMG49956.1 - 1.2e-07 31.6 0.3 1.2e-07 31.6 0.3 2.5 2 0 0 2 2 2 1 HPC2 and ubinuclein domain BCDHK_Adom3 PF10436.9 EMG49957.1 - 4.2e-42 143.7 0.5 6.9e-42 143.0 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EMG49957.1 - 5.4e-08 33.3 0.3 2e-06 28.3 0.1 2.9 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMG49957.1 - 1e-05 25.4 0.1 0.00021 21.1 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IKKbetaNEMObind PF12179.8 EMG49957.1 - 0.084 12.9 0.6 0.49 10.5 0.1 2.6 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain ABC_tran PF00005.27 EMG49958.1 - 1.7e-25 90.1 0.0 5.8e-13 49.5 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMG49958.1 - 4.2e-07 30.1 3.4 0.014 15.2 0.0 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EMG49958.1 - 0.00035 20.7 0.0 0.2 11.9 0.1 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EMG49958.1 - 0.0065 16.7 0.6 0.66 10.2 0.4 3.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMG49958.1 - 0.021 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EMG49958.1 - 0.042 13.6 0.0 0.29 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EMG49958.1 - 1.9 8.9 6.6 0.34 11.4 1.6 2.2 1 1 1 2 2 2 0 AAA domain BSD PF03909.17 EMG49959.1 - 4.6e-14 52.2 1.3 4.6e-14 52.2 1.3 2.8 2 1 1 3 3 3 1 BSD domain Pre-PUA PF17832.1 EMG49959.1 - 0.037 14.7 5.0 0.19 12.4 0.6 2.8 2 0 0 2 2 2 0 Pre-PUA-like domain CHD5 PF04420.14 EMG49959.1 - 0.24 11.2 0.1 0.24 11.2 0.1 3.3 2 1 1 3 3 3 0 CHD5-like protein FliH PF02108.16 EMG49959.1 - 0.52 10.4 6.4 2.2 8.4 6.6 2.0 1 1 0 1 1 1 0 Flagellar assembly protein FliH TraC PF07820.12 EMG49959.1 - 1.3 9.4 0.0 1.3 9.4 0.0 3.2 4 0 0 4 4 4 0 TraC-like protein Dus PF01207.17 EMG49959.1 - 9.7 5.2 8.0 4.2 6.4 2.9 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) UCH PF00443.29 EMG49960.1 - 1e-40 139.8 0.3 1.2e-40 139.6 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMG49960.1 - 1.8e-21 77.1 0.5 2.3e-21 76.8 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2_2 PF12756.7 EMG49960.1 - 0.59 10.5 3.1 14 6.1 0.2 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Aminotran_1_2 PF00155.21 EMG49961.1 - 3.6e-61 207.4 0.0 4.6e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMG49961.1 - 3.6e-05 22.9 0.0 5.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMG49961.1 - 0.0006 19.2 0.0 0.00086 18.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EMG49961.1 - 0.0025 17.2 0.0 0.0089 15.4 0.0 1.8 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 EMG49961.1 - 0.12 11.1 0.0 0.22 10.2 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pkinase PF00069.25 EMG49962.1 - 7.3e-61 205.8 0.0 1.1e-60 205.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG49962.1 - 4.9e-31 107.9 0.0 6.9e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMG49962.1 - 0.0012 17.9 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EMG49962.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EMG49962.1 - 0.025 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Katanin_con80 PF13925.6 EMG49962.1 - 0.053 13.6 0.2 0.097 12.7 0.2 1.3 1 0 0 1 1 1 0 con80 domain of Katanin Rho_GDI PF02115.17 EMG49963.1 - 5.1e-24 85.1 0.2 5.9e-24 84.9 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor SSrecog PF03531.14 EMG49963.1 - 0.089 12.7 0.1 1.4 8.9 0.1 2.2 1 1 1 2 2 2 0 Structure-specific recognition protein (SSRP1) P2_N PF18628.1 EMG49963.1 - 0.11 12.2 0.6 2.8 7.7 0.0 2.1 1 1 1 2 2 2 0 Viral coat protein P2 N-terminal domain Memo PF01875.17 EMG49964.1 - 1.1e-69 234.6 0.0 1.3e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Adaptin_N PF01602.20 EMG49965.1 - 1.2e-92 311.1 11.4 1.5e-92 310.8 11.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EMG49965.1 - 3.3e-39 134.5 2.1 3.3e-39 134.5 2.1 2.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMG49965.1 - 4.8e-17 62.1 0.0 3.5e-06 27.3 0.0 6.0 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.22 EMG49965.1 - 3e-12 45.7 0.1 0.00027 20.9 0.0 6.1 6 0 0 6 6 5 2 HEAT repeat Arm PF00514.23 EMG49965.1 - 3.7e-07 30.0 0.5 0.16 12.0 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EMG49965.1 - 7.3e-06 26.4 0.6 0.15 12.6 0.0 5.7 6 1 1 7 7 7 1 HEAT-like repeat RasGEF_N_2 PF14663.6 EMG49965.1 - 0.0045 17.4 1.4 0.88 10.0 0.2 3.7 2 1 2 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain DNA_alkylation PF08713.11 EMG49965.1 - 0.0085 15.8 0.0 4.6 6.9 0.0 2.7 2 1 1 3 3 3 2 DNA alkylation repair enzyme DUF5578 PF17741.1 EMG49965.1 - 0.009 15.5 1.5 2.2 7.6 0.3 3.7 4 0 0 4 4 4 1 Family of unknown function (DUF5578) CLASP_N PF12348.8 EMG49965.1 - 0.011 15.3 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 0 CLASP N terminal RTP1_C1 PF10363.9 EMG49965.1 - 0.066 13.4 5.0 0.74 10.0 1.1 3.7 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 T_hemolysin PF12261.8 EMG49965.1 - 0.12 12.2 0.0 0.68 9.7 0.0 2.1 2 0 0 2 2 2 0 Thermostable hemolysin FANCI_S2 PF14676.6 EMG49965.1 - 1.4 9.2 4.2 8 6.7 0.3 3.5 3 1 0 3 3 3 0 FANCI solenoid 2 DEAD PF00270.29 EMG49966.1 - 8.8e-26 90.7 0.2 5.3e-24 84.9 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG49966.1 - 7.2e-16 58.5 1.2 7.6e-15 55.2 0.2 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 EMG49966.1 - 2.9e-14 53.6 0.3 1.1e-13 51.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) ResIII PF04851.15 EMG49966.1 - 2.1e-08 34.4 0.3 1.3e-07 31.8 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1548 PF07579.11 EMG49966.1 - 0.027 14.8 0.0 0.31 11.4 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) AA_permease PF00324.21 EMG49968.1 - 2.8e-118 395.6 46.8 3.4e-118 395.3 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG49968.1 - 1.1e-24 87.1 50.5 1.5e-24 86.6 50.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG49969.1 - 3.4e-117 392.0 45.7 4.3e-117 391.7 45.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG49969.1 - 4.2e-30 104.9 48.4 5.7e-30 104.5 48.4 1.1 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 EMG49969.1 - 0.058 13.9 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Pet100 Orthoreo_P10 PF07204.11 EMG49969.1 - 0.47 10.4 2.2 1.5 8.8 2.2 1.9 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 FTR1 PF03239.14 EMG49970.1 - 5.1e-63 213.1 0.9 6.6e-63 212.7 0.9 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family Sec1 PF00995.23 EMG49970.1 - 0.046 13.0 0.1 0.063 12.5 0.1 1.2 1 0 0 1 1 1 0 Sec1 family SHIPPO-rpt PF07004.12 EMG49970.1 - 0.099 13.6 0.3 0.32 12.0 0.0 2.0 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat TMEM100 PF16311.5 EMG49970.1 - 1.7 8.2 7.8 0.34 10.5 3.4 2.0 2 0 0 2 2 2 0 Transmembrane protein 100 UCH PF00443.29 EMG49971.1 - 1.9e-59 201.3 3.2 2.2e-59 201.0 3.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMG49971.1 - 1.4e-24 87.3 5.5 1.8e-23 83.6 5.5 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FTR1 PF03239.14 EMG49972.1 - 2e-17 63.3 0.6 2.2e-17 63.2 0.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Nup188_C PF18378.1 EMG49972.1 - 0.053 12.3 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain FtsX PF02687.21 EMG49972.1 - 0.51 10.8 6.1 0.43 11.1 2.0 2.0 2 0 0 2 2 2 0 FtsX-like permease family CAP PF00188.26 EMG49973.1 - 1.1e-15 58.6 0.3 1.1e-15 58.6 0.3 2.2 2 1 0 2 2 2 1 Cysteine-rich secretory protein family SOG2 PF10428.9 EMG49973.1 - 0.023 13.9 33.6 0.037 13.2 33.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Utp14 PF04615.13 EMG49973.1 - 3.1 6.3 14.1 3.8 5.9 14.1 1.0 1 0 0 1 1 1 0 Utp14 protein SPX PF03105.19 EMG49973.1 - 4.8 7.0 25.4 6.2 6.6 25.4 1.1 1 0 0 1 1 1 0 SPX domain FTR1 PF03239.14 EMG49974.1 - 4.4e-59 200.2 0.8 5.2e-59 199.9 0.8 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family Sec1 PF00995.23 EMG49974.1 - 0.002 17.5 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Sec1 family SHIPPO-rpt PF07004.12 EMG49974.1 - 0.11 13.5 0.2 0.31 12.0 0.0 1.9 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat DSRB PF10781.9 EMG49974.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Dextransucrase DSRB Ras PF00071.22 EMG49975.1 - 1.8e-54 183.7 0.1 2.3e-54 183.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG49975.1 - 5e-37 126.8 0.0 7.2e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG49975.1 - 2.9e-17 62.7 0.1 3.2e-17 62.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMG49975.1 - 2.8e-07 30.1 0.0 3.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMG49975.1 - 3.1e-06 27.3 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMG49975.1 - 0.00013 21.9 0.3 0.12 12.3 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EMG49975.1 - 0.0031 17.1 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EMG49975.1 - 0.014 14.6 0.6 0.038 13.2 0.6 1.9 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 EMG49975.1 - 0.019 15.4 0.0 0.028 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EMG49975.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 EMG49975.1 - 0.078 12.9 0.2 0.14 12.0 0.2 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Cpn10 PF00166.21 EMG49976.1 - 6.3e-30 103.1 0.1 7.1e-30 102.9 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit BP28CT PF08146.12 EMG49977.1 - 4e-41 140.5 8.3 6.2e-40 136.6 1.2 4.1 3 1 0 3 3 3 2 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EMG49977.1 - 1.9e-16 60.4 1.4 1.9e-16 60.4 1.4 4.5 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 DUF3385 PF11865.8 EMG49977.1 - 0.0017 18.3 6.5 0.39 10.6 0.0 4.4 5 1 0 5 5 5 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 EMG49977.1 - 0.097 13.1 0.0 0.8 10.1 0.0 2.7 1 0 0 1 1 1 0 HEAT repeats Rib_5-P_isom_A PF06026.14 EMG49977.1 - 0.11 12.1 4.4 1.5 8.4 0.0 3.2 3 0 0 3 3 3 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF3808 PF10300.9 EMG49978.1 - 1.6e-123 412.9 1.4 2.4e-123 412.4 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_9 PF13371.6 EMG49978.1 - 0.035 14.2 0.2 14 5.9 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMG49978.1 - 0.046 13.8 1.9 2 8.7 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 EMG49978.1 - 3.3 8.1 8.3 8 6.9 8.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain UNC-50 PF05216.13 EMG49979.1 - 1.1e-91 306.4 16.6 1.2e-91 306.2 16.6 1.0 1 0 0 1 1 1 1 UNC-50 family DNA_pol_phi PF04931.13 EMG49980.1 - 0.6 8.1 14.3 0.8 7.7 14.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi TBCC_N PF16752.5 EMG49980.1 - 7.9 7.0 9.9 0.75 10.3 4.9 1.8 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain IBR PF01485.21 EMG49981.1 - 6e-17 61.6 51.1 1.1e-08 35.1 18.6 4.7 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EMG49981.1 - 1.4e-06 28.0 47.6 3e-06 27.0 7.9 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMG49981.1 - 0.00021 21.1 6.1 0.00021 21.1 6.1 4.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMG49981.1 - 0.00031 21.0 49.6 0.00056 20.2 7.5 4.2 2 1 1 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 EMG49981.1 - 0.0089 16.0 8.1 0.0089 16.0 8.1 4.0 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMG49981.1 - 0.0096 15.9 10.1 0.0096 15.9 10.1 3.7 3 0 0 3 3 3 1 zinc-RING finger domain 7TMR-HDED PF07697.11 EMG49981.1 - 0.054 13.6 3.8 0.1 12.7 3.8 1.4 1 0 0 1 1 1 0 7TM-HD extracellular DUF952 PF06108.12 EMG49981.1 - 0.12 12.4 0.0 7.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF952) zf-C3HC4_4 PF15227.6 EMG49981.1 - 7.8 6.7 42.1 0.047 13.9 8.4 4.9 2 1 2 4 4 4 0 zinc finger of C3HC4-type, RING BPL_LplA_LipB PF03099.19 EMG49982.1 - 0.14 12.1 0.1 0.69 9.8 0.0 2.1 3 0 0 3 3 3 0 Biotin/lipoate A/B protein ligase family Pam16 PF03656.13 EMG49983.1 - 6.4e-33 113.5 1.0 7.1e-33 113.3 1.0 1.0 1 0 0 1 1 1 1 Pam16 PHD PF00628.29 EMG49984.1 - 6.7e-07 29.1 11.2 1.4e-06 28.1 11.2 1.6 1 0 0 1 1 1 1 PHD-finger TFIIA PF03153.13 EMG49984.1 - 0.011 15.8 42.4 0.04 13.9 17.5 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L4 PF00573.22 EMG49985.1 - 2.9e-41 141.3 1.5 2.9e-41 141.3 1.5 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EMG49985.1 - 2.6e-30 104.3 2.3 1.6e-29 101.7 1.3 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain GreA_GreB PF01272.19 EMG49986.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term LIP PF03583.14 EMG49987.1 - 1.2e-114 382.5 0.0 1.4e-114 382.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EMG49987.1 - 0.0014 18.1 0.1 0.58 9.6 0.2 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family STAG PF08514.11 EMG49988.1 - 1.3e-27 96.0 1.1 1.3e-27 96.0 1.1 3.7 4 0 0 4 4 4 1 STAG domain DUF1664 PF07889.12 EMG49988.1 - 0.88 9.6 24.0 0.068 13.2 0.9 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) LOH1CR12 PF10158.9 EMG49988.1 - 7.6 6.6 11.4 4.9 7.2 0.2 3.7 3 0 0 3 3 3 0 Tumour suppressor protein WD40 PF00400.32 EMG49989.1 - 5.4e-24 84.0 6.2 6.2e-07 30.0 0.0 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG49989.1 - 2.1e-05 24.7 0.2 2 8.8 0.0 4.8 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMG49989.1 - 0.003 16.6 0.0 2.1 7.2 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SWIRM PF04433.17 EMG49990.1 - 1.2e-29 102.5 1.3 2.5e-29 101.4 0.2 2.3 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 EMG49990.1 - 1.1e-08 35.1 0.0 3e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 EMG49990.1 - 1.1e-06 28.5 11.9 2.6e-06 27.3 11.9 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 EMG49990.1 - 0.00024 21.3 0.2 0.0016 18.6 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain HEPN_RES_NTD1 PF18870.1 EMG49990.1 - 0.015 15.5 0.4 0.13 12.5 0.2 2.6 2 0 0 2 2 2 0 HEPN/RES N-terminal domain 1 ZZ PF00569.17 EMG49990.1 - 0.069 13.0 0.4 0.069 13.0 0.4 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type Chordopox_RPO7 PF05864.12 EMG49990.1 - 0.075 13.3 0.1 0.28 11.4 0.1 2.0 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) LIP PF03583.14 EMG49992.1 - 3.6e-118 394.0 0.0 4.3e-118 393.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.20 EMG49992.1 - 0.019 14.6 0.1 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMG49992.1 - 0.03 13.8 0.1 6.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family RRM_1 PF00076.22 EMG49993.1 - 2.6e-19 68.8 0.1 5.1e-14 51.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EMG49993.1 - 1.1e-05 25.3 0.2 0.083 13.0 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 EMG49993.1 - 0.0023 18.0 0.0 0.047 13.8 0.1 2.1 2 0 0 2 2 2 1 Limkain b1 YflT PF11181.8 EMG49993.1 - 0.19 12.3 0.6 0.47 11.0 0.2 1.8 2 0 0 2 2 2 0 Heat induced stress protein YflT eIF3g PF12353.8 EMG49995.1 - 3.4e-45 153.5 3.5 5.4e-45 152.8 3.5 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EMG49995.1 - 2.4e-16 59.3 0.0 4.1e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMG49995.1 - 0.082 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AMPK1_CBM PF16561.5 EMG49997.1 - 8.3e-17 61.2 0.0 1.7e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 EMG49997.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) NARP1 PF12569.8 EMG49997.1 - 0.09 11.7 3.2 0.12 11.2 3.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Macoilin PF09726.9 EMG49997.1 - 0.29 9.6 4.1 0.37 9.3 4.1 1.1 1 0 0 1 1 1 0 Macoilin family zf-H2C2_2 PF13465.6 EMG49998.1 - 0.00016 22.0 3.2 0.00016 22.0 3.2 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EMG49998.1 - 0.00068 20.0 3.0 0.00068 20.0 3.0 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type TFIIA PF03153.13 EMG49998.1 - 0.0021 18.1 84.0 0.0046 17.0 32.6 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit zf-C2H2_4 PF13894.6 EMG49998.1 - 0.0034 18.1 1.9 0.0034 18.1 1.9 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.7 EMG49998.1 - 0.019 15.4 1.1 0.019 15.4 1.1 3.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 EMG49998.1 - 0.19 12.1 3.3 0.76 10.1 3.3 2.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon tRNA_Me_trans PF03054.16 EMG49999.1 - 1e-115 386.4 0.0 1.2e-115 386.2 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 EMG49999.1 - 0.0009 18.4 0.0 0.0056 15.8 0.0 2.0 2 0 0 2 2 2 1 NAD synthase QueC PF06508.13 EMG49999.1 - 0.065 12.7 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC FAA_hydrolase PF01557.18 EMG50000.1 - 6e-52 176.5 0.0 7.3e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family dCMP_cyt_deam_1 PF00383.23 EMG50001.1 - 3.7e-15 55.7 0.0 5.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.6 EMG50001.1 - 3e-06 27.8 0.0 5.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain MafB19-deam PF14437.6 EMG50001.1 - 2.2e-05 24.2 0.0 4.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 MafB19-like deaminase CoaE PF01121.20 EMG50001.1 - 0.015 14.9 0.0 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase Cytidylate_kin2 PF13189.6 EMG50001.1 - 0.029 14.5 0.2 4.1 7.5 0.0 2.4 2 1 0 2 2 2 0 Cytidylate kinase-like family NPC1_N PF16414.5 EMG50002.1 - 3.5e-77 259.3 14.2 3.5e-77 259.3 14.2 1.8 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Patched PF02460.18 EMG50002.1 - 7.7e-65 219.4 28.3 1.3e-60 205.5 18.2 3.0 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 EMG50002.1 - 3.7e-48 163.2 6.9 3.7e-48 163.2 6.9 3.2 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Pox_P35 PF03213.14 EMG50002.1 - 0.0037 16.5 1.0 0.008 15.4 1.0 1.4 1 0 0 1 1 1 1 Poxvirus P35 protein ACR_tran PF00873.19 EMG50002.1 - 4.9 4.7 13.3 11 3.6 13.3 1.5 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TMEM132D_C PF15706.5 EMG50003.1 - 0.059 13.2 0.0 0.2 11.4 0.0 2.0 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF3481 PF11980.8 EMG50003.1 - 0.23 11.2 3.5 0.25 11.1 1.1 2.2 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein Mitofilin PF09731.9 EMG50003.1 - 1.2 7.9 13.2 1.8 7.3 13.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PMP1_2 PF08114.11 EMG50003.1 - 2.2 8.1 4.4 4.3 7.2 4.4 1.4 1 0 0 1 1 1 0 ATPase proteolipid family PPI_Ypi1 PF07491.11 EMG50004.1 - 1.5e-23 82.4 17.1 1.5e-23 82.4 17.1 2.1 2 1 0 2 2 2 1 Protein phosphatase inhibitor PPR_2 PF13041.6 EMG50005.1 - 0.00022 21.3 0.1 0.0015 18.7 0.1 2.6 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 EMG50005.1 - 0.041 14.0 0.1 0.041 14.0 0.1 2.7 3 0 0 3 3 3 0 Pentatricopeptide repeat domain HATPase_c_3 PF13589.6 EMG50006.1 - 5.1e-13 49.0 0.2 1.7e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 EMG50006.1 - 8.5e-13 48.3 0.4 4.5e-12 46.0 0.4 2.1 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 EMG50006.1 - 5.7e-08 33.3 0.1 1.3e-07 32.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF327 PF03885.13 EMG50006.1 - 0.063 13.2 2.7 8.4 6.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF327) DNA_RNApol_7kD PF03604.13 EMG50007.1 - 3.9e-16 58.4 3.3 5.2e-16 58.0 3.3 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 EMG50007.1 - 0.00098 19.1 0.2 0.001 19.1 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_5 PF13719.6 EMG50007.1 - 0.0021 17.8 1.7 0.066 13.0 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Prok-RING_1 PF14446.6 EMG50007.1 - 0.0033 17.3 0.5 0.0043 16.9 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 TackOD1 PF18551.1 EMG50007.1 - 0.0039 16.9 0.6 0.0043 16.7 0.6 1.1 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 zinc-ribbon_6 PF10005.9 EMG50007.1 - 0.0049 17.5 0.7 0.0063 17.2 0.7 1.2 1 0 0 1 1 1 1 zinc-ribbon domain C1_1 PF00130.22 EMG50007.1 - 0.012 15.4 1.0 0.017 15.0 1.0 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ZZ PF00569.17 EMG50007.1 - 0.02 14.7 1.1 3.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type TFIIS_C PF01096.18 EMG50007.1 - 0.024 14.5 0.5 2.1 8.3 0.2 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 EMG50007.1 - 0.026 14.6 2.9 0.061 13.5 2.9 1.6 1 1 0 1 1 1 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 EMG50007.1 - 0.036 14.0 0.4 0.049 13.6 0.4 1.2 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf_UBZ PF18439.1 EMG50007.1 - 0.04 13.5 1.5 5.2 6.7 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 EMG50007.1 - 0.043 13.9 1.2 0.088 12.8 1.2 1.6 1 1 0 1 1 1 0 Double zinc ribbon FYDLN_acid PF09538.10 EMG50007.1 - 0.11 13.2 0.3 0.12 13.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_13 PF09855.9 EMG50007.1 - 0.17 12.1 2.0 0.17 12.1 0.1 1.8 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc_ribbon_4 PF13717.6 EMG50007.1 - 0.18 11.7 4.6 2.4 8.2 4.6 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 EMG50007.1 - 0.51 10.1 4.4 3.9 7.3 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain MFS_1 PF07690.16 EMG50008.1 - 3.9e-42 144.4 40.1 1.3e-40 139.4 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG50008.1 - 1.1e-14 54.2 18.0 1.7e-14 53.5 18.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EMG50008.1 - 4.3e-05 22.1 2.0 4.3e-05 22.1 2.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EMG50008.1 - 0.0019 17.5 1.2 0.0019 17.5 1.2 2.2 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB Acetyltransf_10 PF13673.7 EMG50009.1 - 1.5e-14 54.0 0.0 2.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMG50009.1 - 1.9e-12 47.4 0.0 4e-12 46.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMG50009.1 - 1.2e-06 28.8 0.0 2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3245 PF11595.8 EMG50009.1 - 0.0044 17.5 2.0 0.0069 16.9 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) FR47 PF08445.10 EMG50009.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 EMG50009.1 - 0.086 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tom22 PF04281.13 EMG50009.1 - 0.092 12.5 1.3 0.14 12.0 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 SAM35 PF10806.8 EMG50010.1 - 1.3e-19 70.7 0.0 2.5e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex UCH PF00443.29 EMG50011.1 - 5.8e-10 39.1 0.5 1.1e-09 38.2 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EMG50011.1 - 5.7e-09 36.2 0.6 1.3e-08 35.0 0.6 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EMG50011.1 - 0.0018 17.9 2.0 0.002 17.8 0.4 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Endopep_inhib PF16800.5 EMG50011.1 - 0.17 11.8 1.5 3.8 7.4 0.5 2.7 2 1 0 2 2 2 0 IseA DL-endopeptidase inhibitor JAB PF01398.21 EMG50012.1 - 1.4e-32 112.1 0.2 1.4e-32 112.1 0.2 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EMG50012.1 - 2.4e-13 50.5 1.0 5.8e-13 49.2 1.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EMG50012.1 - 3.2e-07 30.1 0.0 5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Peptidase_M24 PF00557.24 EMG50013.1 - 1e-55 188.7 0.0 1.3e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EMG50013.1 - 4.6e-23 81.3 0.0 1.3e-22 79.8 0.0 1.8 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 EMG50013.1 - 0.057 13.5 0.2 0.17 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) GDI PF00996.18 EMG50014.1 - 2.6e-209 695.2 0.0 2.9e-209 695.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor MetOD1 PF18546.1 EMG50014.1 - 0.2 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Metanogen output domain 1 LRR_4 PF12799.7 EMG50015.1 - 4.1e-11 42.9 34.6 0.00052 20.4 2.7 8.8 8 1 1 9 9 9 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG50015.1 - 5.6e-11 42.0 21.3 0.00051 19.8 5.8 7.3 5 2 2 7 7 7 2 Leucine rich repeat FNIP PF05725.12 EMG50015.1 - 5.5e-06 26.5 30.5 0.04 14.1 1.3 7.9 8 0 0 8 8 8 3 FNIP Repeat LRR_6 PF13516.6 EMG50015.1 - 0.0015 18.4 14.2 12 6.3 0.0 7.6 8 0 0 8 8 8 2 Leucine Rich repeat F-box PF00646.33 EMG50015.1 - 0.045 13.7 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 F-box domain DUF4476 PF14771.6 EMG50015.1 - 0.11 12.8 0.0 0.39 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) LRR_5 PF13306.6 EMG50015.1 - 0.53 10.2 3.2 9.5 6.2 0.2 3.1 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EMG50016.1 - 3.1e-13 49.3 24.0 8.7e-07 28.6 4.8 6.4 5 2 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 EMG50016.1 - 7.4e-11 42.1 31.6 0.025 15.0 0.0 9.4 8 1 1 9 9 9 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EMG50016.1 - 0.075 12.9 0.1 0.22 11.5 0.1 1.8 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.6 EMG50016.1 - 4.2 7.7 18.0 2.8 8.2 0.1 6.9 8 0 0 8 8 8 0 Leucine Rich repeat Aldo_ket_red PF00248.21 EMG50017.1 - 5.3e-36 124.3 0.1 7.1e-35 120.6 0.1 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Asp_protease PF09668.10 EMG50018.1 - 1.4e-31 108.9 0.0 2.3e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EMG50018.1 - 7e-12 45.8 0.2 3.9e-11 43.4 0.1 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 EMG50018.1 - 3.7e-10 39.4 0.0 8.8e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 EMG50018.1 - 6.6e-07 29.9 0.1 1.5e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Rad60-SLD PF11976.8 EMG50018.1 - 8.9e-06 25.5 0.0 2.3e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RsmJ PF04378.13 EMG50018.1 - 0.01 15.1 0.3 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Ribosomal RNA large subunit methyltransferase D, RlmJ Ubiquitin_2 PF14560.6 EMG50018.1 - 0.023 15.1 0.1 0.05 14.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain FlgM PF04316.13 EMG50018.1 - 3.8 7.9 6.1 1.2 9.6 1.3 2.5 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM MFS_1 PF07690.16 EMG50019.1 - 1.9e-39 135.6 29.1 1.9e-39 135.6 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG50019.1 - 2.5e-08 33.2 27.7 2.5e-07 29.9 27.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EMG50019.1 - 6e-05 21.7 3.0 0.00011 20.7 3.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Amidohydro_1 PF01979.20 EMG50020.1 - 8.2e-12 45.1 0.0 1.7e-11 44.0 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMG50020.1 - 1.5e-10 41.1 0.0 3.3e-06 26.9 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family Glucosamine_iso PF01182.20 EMG50021.1 - 2.6e-19 70.0 0.0 5.1e-19 69.1 0.0 1.4 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.16 EMG50022.1 - 3.6e-54 183.7 0.1 5.5e-54 183.1 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EMG50022.1 - 6.7e-30 104.5 0.0 9.6e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FWWh PF14922.6 EMG50022.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function RHD3 PF05879.12 EMG50023.1 - 3.7e-267 888.3 19.9 4.5e-267 888.1 19.9 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EMG50023.1 - 1.5e-08 34.3 0.1 2.8e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EMG50023.1 - 3.5e-05 23.9 0.3 0.00011 22.3 0.3 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EMG50023.1 - 0.00013 22.1 0.0 0.00052 20.1 0.0 2.1 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 EMG50023.1 - 0.001 19.3 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMG50023.1 - 0.075 13.4 0.1 0.78 10.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 EMG50023.1 - 0.089 13.0 1.6 0.2 11.9 0.1 2.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ETF PF01012.21 EMG50024.1 - 3e-39 134.8 2.2 4.7e-39 134.2 2.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EMG50024.1 - 1.2e-34 118.2 0.4 9e-34 115.4 0.2 2.2 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain SIS_2 PF13580.6 EMG50024.1 - 0.064 13.3 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 SIS domain Sulfate_transp PF00916.20 EMG50025.1 - 1.2e-78 264.5 14.3 1.7e-78 264.0 14.3 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EMG50025.1 - 1.2e-16 60.3 0.1 2.8e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 STAS domain CAF1C_H4-bd PF12265.8 EMG50026.1 - 1.1e-22 80.1 0.5 2.6e-22 78.8 0.5 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EMG50026.1 - 1.9e-15 57.0 10.3 2.2e-05 25.1 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50026.1 - 7.5e-09 35.8 2.0 0.00084 19.6 0.0 5.2 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain BING4CT PF08149.11 EMG50026.1 - 0.00028 20.6 0.0 5.8 6.8 0.0 3.6 3 0 0 3 3 3 2 BING4CT (NUC141) domain eIF2A PF08662.11 EMG50026.1 - 0.00033 20.6 3.0 0.013 15.4 0.6 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF2415 PF10313.9 EMG50026.1 - 0.12 12.3 0.0 6.4 6.8 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) DUF3704 PF12488.8 EMG50027.1 - 0.14 11.8 3.0 0.49 10.1 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) ATE_C PF04377.15 EMG50029.1 - 4.1e-48 163.4 0.0 1.1e-47 162.1 0.0 1.7 1 1 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EMG50029.1 - 6.8e-22 77.6 3.4 1.3e-21 76.7 3.4 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Sod_Cu PF00080.20 EMG50030.1 - 3.8e-14 53.1 0.4 6.7e-14 52.3 0.4 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ECM11 PF15463.6 EMG50030.1 - 0.12 12.9 0.5 0.2 12.2 0.5 1.3 1 0 0 1 1 1 0 Extracellular mutant protein 11 DUF1335 PF07056.11 EMG50030.1 - 0.16 12.0 0.3 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) Mito_carr PF00153.27 EMG50031.1 - 1.2e-61 204.6 1.7 4.1e-23 81.1 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMG50031.1 - 0.0024 17.1 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 2 Gammaproteobacterial serine protease DUF1279 PF06916.13 EMG50032.1 - 2.1e-32 111.5 0.1 3.2e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3196 PF11428.8 EMG50032.1 - 0.016 14.7 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) Bac_small_YrzI PF09501.10 EMG50032.1 - 7.8 6.7 6.2 5.2 7.3 3.2 2.1 2 1 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Uricase PF01014.18 EMG50033.1 - 6.6e-51 172.0 5.9 4.2e-34 117.6 1.6 2.7 3 0 0 3 3 3 2 Uricase ThiF PF00899.21 EMG50033.1 - 3.2e-44 151.1 0.0 6.3e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EMG50033.1 - 0.00079 19.7 1.8 0.016 15.5 1.8 2.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EMG50033.1 - 0.0018 17.9 0.2 0.0047 16.5 0.2 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 EMG50033.1 - 0.006 16.6 0.1 0.018 15.1 0.1 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EMG50033.1 - 0.0089 15.7 0.1 0.026 14.2 0.1 1.8 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 EMG50033.1 - 0.014 14.7 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMG50033.1 - 0.023 15.0 0.1 0.11 12.8 0.1 2.2 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 EMG50033.1 - 0.025 13.8 0.2 0.059 12.6 0.2 1.6 1 0 0 1 1 1 0 FAD binding domain DUF3530 PF12048.8 EMG50033.1 - 0.033 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PglD_N PF17836.1 EMG50033.1 - 0.05 14.2 0.6 0.35 11.5 0.1 2.7 3 0 0 3 3 3 0 PglD N-terminal domain 3HCDH_N PF02737.18 EMG50033.1 - 0.055 13.3 0.7 0.59 10.0 0.1 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 EMG50033.1 - 0.057 13.0 0.3 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMG50033.1 - 0.13 12.8 0.2 0.59 10.7 0.2 2.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pex24p PF06398.11 EMG50034.1 - 8.4e-100 334.3 17.7 1.4e-99 333.6 17.7 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Prp18 PF02840.15 EMG50035.1 - 1.6e-39 135.2 0.9 1.6e-39 135.2 0.9 2.3 2 2 0 2 2 2 1 Prp18 domain TFIIF_beta PF02270.15 EMG50036.1 - 5.7e-30 103.3 0.7 8.4e-30 102.7 0.7 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 EMG50036.1 - 7.1e-06 26.7 2.0 7.8e-06 26.6 0.1 2.0 3 0 0 3 3 3 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 EMG50036.1 - 0.0015 19.3 0.0 0.0023 18.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain NDT80_PhoG PF05224.12 EMG50037.1 - 3.9e-60 203.3 0.7 3.9e-60 203.3 0.7 3.8 2 1 1 3 3 3 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_76 PF03663.14 EMG50038.1 - 2.8e-28 99.5 11.7 3.7e-28 99.1 11.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMG50038.1 - 2.5e-06 26.8 1.9 9.7e-06 24.9 1.8 1.9 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 EMG50038.1 - 3.6e-06 26.6 0.9 0.0015 18.1 0.0 2.4 1 1 1 2 2 2 2 D-glucuronyl C5-epimerase C-terminus GlcNAc_2-epim PF07221.11 EMG50038.1 - 0.0085 15.4 0.0 0.066 12.4 0.0 2.4 2 1 1 3 3 3 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_127 PF07944.12 EMG50038.1 - 0.012 14.1 0.0 0.032 12.7 0.0 1.5 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 LANC_like PF05147.13 EMG50038.1 - 0.033 12.8 1.0 4.8 5.6 0.1 2.7 2 1 1 3 3 3 0 Lanthionine synthetase C-like protein ABC2_membrane_3 PF12698.7 EMG50038.1 - 0.52 9.4 5.5 0.17 11.0 2.8 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2401 PF10287.9 EMG50039.1 - 1.6e-80 270.0 2.5 1.6e-80 270.0 2.5 2.0 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EMG50039.1 - 2.4e-24 85.5 1.1 3.8e-24 84.9 0.1 1.9 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) DUF1522 PF07482.11 EMG50039.1 - 0.0022 18.3 3.5 0.024 15.0 2.8 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1522) MscS_porin PF12795.7 EMG50040.1 - 0.0061 16.1 26.5 0.026 14.1 17.7 2.5 2 1 0 2 2 2 2 Mechanosensitive ion channel porin domain DUF3584 PF12128.8 EMG50040.1 - 0.01 13.4 23.1 0.013 13.1 23.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) bZIP_2 PF07716.15 EMG50040.1 - 0.084 13.0 0.5 0.084 13.0 0.5 4.1 3 1 1 4 4 4 0 Basic region leucine zipper Fer4_24 PF18109.1 EMG50040.1 - 0.28 11.5 8.8 0.52 10.6 0.7 3.4 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain BCAS2 PF05700.11 EMG50040.1 - 0.66 9.6 15.4 0.034 13.8 8.9 2.0 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) APG6_N PF17675.1 EMG50040.1 - 0.71 10.4 32.2 10 6.7 21.3 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region CtIP_N PF10482.9 EMG50040.1 - 1.2 9.2 29.0 0.055 13.5 10.7 3.4 1 1 2 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Fez1 PF06818.15 EMG50040.1 - 1.3 9.4 29.2 4 7.8 17.9 2.5 1 1 2 3 3 3 0 Fez1 YvrJ PF12841.7 EMG50040.1 - 1.5 8.4 4.6 15 5.2 1.3 3.0 2 0 0 2 2 2 0 YvrJ protein family DUF5082 PF16888.5 EMG50040.1 - 1.9 8.8 35.4 0.15 12.3 19.3 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Snapin_Pallidin PF14712.6 EMG50040.1 - 6.7 7.2 33.0 6.8 7.2 6.6 4.1 1 1 3 4 4 4 0 Snapin/Pallidin DUF4407 PF14362.6 EMG50040.1 - 8.2 5.7 20.0 30 3.9 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Mpp10 PF04006.12 EMG50041.1 - 4.6e-142 474.6 70.9 5.8e-142 474.3 70.9 1.0 1 0 0 1 1 1 1 Mpp10 protein Apis_Csd PF11671.8 EMG50041.1 - 5.9 6.9 9.4 25 4.8 9.4 2.0 1 0 0 1 1 1 0 Complementary sex determiner protein SSF PF00474.17 EMG50042.1 - 9.3e-19 67.6 18.8 9.3e-19 67.6 18.8 2.3 2 1 0 2 2 2 1 Sodium:solute symporter family peroxidase PF00141.23 EMG50043.1 - 5.7e-48 163.6 0.0 1.2e-47 162.5 0.0 1.6 2 0 0 2 2 2 1 Peroxidase Say1_Mug180 PF10340.9 EMG50043.1 - 2.2e-26 92.6 2.8 1.7e-25 89.7 2.8 2.2 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EMG50043.1 - 2.1e-15 57.2 0.0 3.9e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF816 PF05674.12 EMG50043.1 - 0.052 13.5 0.3 0.12 12.3 0.3 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Psm4 PF17063.5 EMG50043.1 - 0.19 12.4 1.3 1.3 9.7 0.6 2.6 2 0 0 2 2 2 0 Phenol-soluble modulin alpha 4 peptide G-patch_2 PF12656.7 EMG50044.1 - 7e-10 38.9 0.4 3e-09 36.8 0.4 2.1 1 1 0 1 1 1 1 G-patch domain Rad17 PF03215.15 EMG50045.1 - 8.4e-05 22.6 3.7 0.043 13.7 0.0 3.7 3 1 1 4 4 4 2 Rad17 P-loop domain Peptidase_U32_C PF16325.5 EMG50045.1 - 0.046 14.0 0.2 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Peptidase family U32 C-terminal domain AAA PF00004.29 EMG50045.1 - 0.12 12.7 0.0 0.36 11.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RRN3 PF05327.11 EMG50046.1 - 1.2e-180 601.8 11.7 1.4e-180 601.6 11.7 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 EMG50046.1 - 0.0058 16.0 4.2 0.0099 15.3 4.2 1.4 1 0 0 1 1 1 1 BUD22 Nop53 PF07767.11 EMG50046.1 - 0.014 14.8 2.2 0.022 14.1 2.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CHASE6_C PF17150.4 EMG50046.1 - 0.083 13.6 0.3 6.5 7.5 0.0 3.3 2 2 1 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain CobT PF06213.12 EMG50046.1 - 1.2 8.5 11.0 2 7.7 11.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid_p PF12226.8 EMG50046.1 - 1.8 7.7 18.9 0.46 9.6 14.8 1.9 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Hyphal_reg_CWP PF11765.8 EMG50047.1 - 2.7e-22 79.2 0.2 4e-22 78.6 0.2 1.3 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 EMG50047.1 - 1.5e-16 59.7 34.3 1.3e-06 27.8 6.9 4.4 4 0 0 4 4 4 4 Hyphally regulated cell wall GPI-anchored protein 1 DUF5628 PF18621.1 EMG50047.1 - 0.13 12.8 8.9 3 8.3 0.6 3.6 2 1 2 4 4 4 0 Family of unknown function (DUF5628) Pput2613-deam PF14427.6 EMG50047.1 - 0.22 11.4 1.1 5.1 7.0 0.2 2.5 1 1 2 3 3 3 0 Pput_2613-like deaminase Pput2613-deam PF14427.6 EMG50049.1 - 0.0068 16.3 5.2 0.083 12.8 1.3 2.2 1 1 1 2 2 2 2 Pput_2613-like deaminase Catalase_C PF18011.1 EMG50049.1 - 0.2 11.3 3.0 12 5.5 0.1 2.8 1 1 2 3 3 3 0 C-terminal domain found in long catalases DUF3254 PF11630.8 EMG50049.1 - 2.3 8.4 5.4 5.3 7.3 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3254) DUF5628 PF18621.1 EMG50049.1 - 3.8 8.0 15.1 11 6.5 1.0 3.2 1 1 2 3 3 3 0 Family of unknown function (DUF5628) Hyr1 PF15789.5 EMG50049.1 - 6.2 6.4 53.0 0.28 10.8 13.0 4.3 4 2 0 4 4 4 0 Hyphally regulated cell wall GPI-anchored protein 1 Hyr1 PF15789.5 EMG50050.1 - 7.3e-16 57.4 68.1 7.4e-08 31.8 9.5 5.3 4 1 1 5 5 5 4 Hyphally regulated cell wall GPI-anchored protein 1 DUF3254 PF11630.8 EMG50050.1 - 0.11 12.6 3.8 0.35 11.1 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3254) DUF5628 PF18621.1 EMG50050.1 - 0.22 12.0 19.5 0.5 10.9 0.5 3.9 1 1 3 4 4 4 0 Family of unknown function (DUF5628) NifU PF01106.17 EMG50052.1 - 1.5e-28 98.7 0.0 2.4e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 EMG50052.1 - 5.4e-09 36.0 0.0 1.6e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal SRPRB PF09439.10 EMG50053.1 - 6.4e-32 110.4 0.0 8.4e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EMG50053.1 - 3.2e-11 43.0 0.0 4.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMG50053.1 - 2.2e-07 30.9 0.1 2.2e-07 30.9 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EMG50053.1 - 2.6e-06 27.0 0.1 3.3e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EMG50053.1 - 1.7e-05 24.7 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EMG50053.1 - 3.4e-05 23.4 0.3 9.2e-05 22.0 0.3 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 EMG50053.1 - 0.0031 17.1 0.0 0.0058 16.2 0.0 1.4 1 1 0 1 1 1 1 Ras family EF-hand_2 PF09068.11 EMG50053.1 - 0.005 17.0 0.0 0.0081 16.3 0.0 1.3 1 0 0 1 1 1 1 EF hand Roc PF08477.13 EMG50053.1 - 0.019 15.1 0.0 0.038 14.2 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EMG50053.1 - 0.061 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EMG50053.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MLANA PF14991.6 EMG50053.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A G-alpha PF00503.20 EMG50053.1 - 0.18 10.9 1.1 1.3 8.1 1.1 2.0 1 1 0 1 1 1 0 G-protein alpha subunit Metallophos PF00149.28 EMG50054.1 - 1.6e-40 139.8 0.1 2.2e-40 139.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EMG50054.1 - 5.9e-23 81.1 0.7 1.1e-22 80.2 0.4 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF4049 PF13258.6 EMG50054.1 - 0.13 11.4 0.0 0.42 9.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4049) Vfa1 PF08432.10 EMG50055.1 - 1.7e-43 149.1 0.7 1.9e-43 148.9 0.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 PI3K_P85_iSH2 PF16454.5 EMG50055.1 - 0.095 12.3 4.7 2.7 7.6 0.1 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Ribosomal_S27e PF01667.17 EMG50056.1 - 2.5e-29 100.7 6.0 3.1e-29 100.4 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 RRM_1 PF00076.22 EMG50057.1 - 0.00089 19.0 7.5 0.012 15.4 0.2 3.8 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.9 EMG50057.1 - 0.0041 16.8 6.9 0.0041 16.8 6.9 3.7 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein Sigma70_ner PF04546.13 EMG50057.1 - 0.02 14.8 15.3 0.33 10.8 1.7 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2052 PF09747.9 EMG50057.1 - 0.028 14.6 22.7 0.071 13.2 0.8 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) MAM33 PF02330.16 EMG50057.1 - 0.13 12.2 26.9 0.025 14.5 2.0 3.5 3 0 0 3 3 3 0 Mitochondrial glycoprotein DARPP-32 PF05395.12 EMG50057.1 - 8.6 6.6 29.6 0.41 10.9 8.4 3.5 3 0 0 3 3 3 0 Protein phosphatase inhibitor 1/DARPP-32 DUF3391 PF11871.8 EMG50057.1 - 9.8 6.7 18.1 2.9 8.4 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) NAD_binding_1 PF00175.21 EMG50058.1 - 1.2e-10 42.0 0.0 3.3e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EMG50058.1 - 4.1e-10 39.9 0.0 6.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 EMG50058.1 - 2.7e-09 37.6 0.1 1.3e-08 35.3 0.0 2.2 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 EMG50058.1 - 0.0068 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 EMG50058.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Protoglobin FAD_binding_6 PF00970.24 EMG50059.1 - 4.9e-08 33.2 0.0 8.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 EMG50059.1 - 6.9e-08 33.0 0.2 1.3e-07 32.1 0.2 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 EMG50059.1 - 1.4e-07 32.1 0.0 2.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EMG50059.1 - 0.037 14.2 0.1 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Ferric reductase NAD binding domain W2 PF02020.18 EMG50059.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Sugar_tr PF00083.24 EMG50060.1 - 1.4e-106 357.1 28.7 1.8e-106 356.8 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG50060.1 - 1.6e-22 80.0 26.2 1.6e-22 80.0 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CDC45 PF02724.14 EMG50061.1 - 1.9e-112 376.7 9.0 3.4e-108 362.6 9.0 3.3 1 1 0 1 1 1 1 CDC45-like protein Sigma70_ner PF04546.13 EMG50061.1 - 0.0041 17.0 3.0 0.0041 17.0 3.0 1.9 3 0 0 3 3 3 1 Sigma-70, non-essential region FAM176 PF14851.6 EMG50061.1 - 1.7 8.3 6.3 1.6 8.4 3.5 2.2 2 0 0 2 2 2 0 FAM176 family BUD22 PF09073.10 EMG50061.1 - 1.8 7.8 7.0 3.2 7.0 7.0 1.3 1 0 0 1 1 1 0 BUD22 YqfQ PF14181.6 EMG50061.1 - 2.2 8.4 4.1 5.2 7.2 4.1 1.5 1 0 0 1 1 1 0 YqfQ-like protein Chorismate_synt PF01264.21 EMG50062.1 - 2e-139 463.9 0.0 2.3e-139 463.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase APH PF01636.23 EMG50063.1 - 2.8e-32 112.6 0.0 3.4e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMG50063.1 - 1.9e-07 30.9 0.1 3.7e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EMG50063.1 - 5e-06 26.0 0.1 7.7e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EMG50063.1 - 0.0022 16.9 0.3 0.0041 16.0 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 EMG50063.1 - 0.14 11.5 2.4 1.6 8.1 0.1 2.9 4 0 0 4 4 4 0 Protein kinase domain FAD_binding_3 PF01494.19 EMG50064.1 - 7.6e-75 252.3 0.0 3.8e-72 243.5 0.0 2.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EMG50064.1 - 1.7e-45 155.0 0.0 3.6e-45 154.0 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EMG50064.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMG50064.1 - 0.027 13.2 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EMG50064.1 - 0.034 13.4 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EMG50064.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EMG50064.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 EMG50064.1 - 0.18 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EMG50064.1 - 0.19 10.8 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF1712 PF08217.11 EMG50065.1 - 8.9e-20 70.7 12.4 8e-17 61.0 9.3 3.3 1 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) ADH_N PF08240.12 EMG50066.1 - 0.0027 17.6 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FAD_binding_6 PF00970.24 EMG50067.1 - 3.9e-10 40.0 0.0 7.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EMG50067.1 - 1.2e-06 29.1 0.0 4.3e-06 27.3 0.0 1.9 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.22 EMG50067.1 - 0.0032 18.0 0.0 0.0064 17.0 0.0 1.6 1 0 0 1 1 1 1 Globin LMBR1 PF04791.16 EMG50070.1 - 4.9e-71 240.2 34.8 6.6e-71 239.7 34.8 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Trigger_C PF05698.14 EMG50070.1 - 0.37 10.8 1.5 34 4.4 0.1 2.8 3 0 0 3 3 3 0 Bacterial trigger factor protein (TF) C-terminus PP2C PF00481.21 EMG50071.1 - 1.2e-42 146.3 0.1 4.5e-38 131.4 0.1 3.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EMG50071.1 - 0.0043 16.7 0.0 0.011 15.4 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EMG50071.1 - 0.12 12.3 0.1 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DEAD PF00270.29 EMG50072.1 - 2.2e-38 131.8 1.6 5.1e-38 130.6 0.1 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG50072.1 - 5.6e-24 84.6 2.2 1.4e-23 83.3 1.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG50072.1 - 2e-08 34.5 0.0 2e-08 34.5 0.0 2.9 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit SDA1 PF05285.12 EMG50072.1 - 3.2 7.1 20.7 5.5 6.3 20.7 1.3 1 0 0 1 1 1 0 SDA1 T3SchapCesA PF11439.8 EMG50073.1 - 0.0027 17.8 0.2 0.0032 17.6 0.2 1.0 1 0 0 1 1 1 1 Type III secretion system filament chaperone CesA DASH_Duo1 PF08651.10 EMG50073.1 - 0.038 13.8 0.2 0.052 13.3 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF948 PF06103.11 EMG50073.1 - 0.05 13.9 0.5 0.061 13.6 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Sugar_tr PF00083.24 EMG50074.1 - 1.2e-106 357.3 25.1 1.4e-106 357.1 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG50074.1 - 3.1e-20 72.4 25.4 3.1e-20 72.4 25.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Spt5_N PF11942.8 EMG50075.1 - 2 9.5 18.3 13 6.8 0.3 3.6 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Pes-10 PF07149.11 EMG50075.1 - 2.5 7.1 7.1 4.3 6.3 7.1 1.4 1 0 0 1 1 1 0 Pes-10 PTPRCAP PF15713.5 EMG50075.1 - 3.4 8.0 14.9 0.042 14.1 2.6 2.7 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated PDDEXK_6 PF04720.12 EMG50075.1 - 9.2 6.1 9.1 1.3 9.0 3.0 2.2 2 0 0 2 2 2 0 PDDEXK-like family of unknown function ASF1_hist_chap PF04729.13 EMG50076.1 - 3.9e-71 238.0 0.0 5.5e-71 237.5 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Radial_spoke PF04712.12 EMG50076.1 - 0.015 14.2 12.1 0.021 13.8 12.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein TFB6 PF17110.5 EMG50076.1 - 0.23 11.2 5.9 0.35 10.6 5.9 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RXT2_N PF08595.11 EMG50076.1 - 0.36 10.9 13.9 0.18 11.8 11.9 1.5 1 1 0 1 1 1 0 RXT2-like, N-terminal Usp PF00582.26 EMG50076.1 - 0.44 11.0 3.8 0.77 10.3 3.8 1.5 1 0 0 1 1 1 0 Universal stress protein family FAM176 PF14851.6 EMG50076.1 - 1.2 8.8 11.3 2.2 7.9 11.3 1.5 1 0 0 1 1 1 0 FAM176 family DUF3402 PF11882.8 EMG50076.1 - 2.5 7.1 4.6 3.6 6.6 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) CDC45 PF02724.14 EMG50076.1 - 7.3 4.8 16.6 8.9 4.5 16.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EMG50076.1 - 7.4 4.6 23.0 8.7 4.4 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EMG50076.1 - 7.7 5.7 20.4 8.6 5.6 20.4 1.1 1 0 0 1 1 1 0 BUD22 RICTOR_N PF14664.6 EMG50078.1 - 3.5e-114 381.7 17.9 6.6e-114 380.8 17.9 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 EMG50078.1 - 7.8e-28 96.5 0.4 7.8e-28 96.5 0.4 4.5 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 EMG50078.1 - 1.9e-27 95.1 0.5 1.9e-27 95.1 0.5 6.3 8 0 0 8 8 8 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EMG50078.1 - 6e-24 84.5 11.0 2e-23 82.9 0.1 5.6 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HPIH PF13323.6 EMG50078.1 - 0.00067 19.5 0.0 0.0021 17.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain with HPIH motif HEAT PF02985.22 EMG50078.1 - 0.07 13.4 0.0 37 4.9 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Mem_trans PF03547.18 EMG50079.1 - 3.2e-44 150.9 1.6 3.7e-44 150.7 1.6 1.0 1 0 0 1 1 1 1 Membrane transport protein DDE_1 PF03184.19 EMG50080.1 - 0.11 12.1 0.1 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease adh_short_C2 PF13561.6 EMG50081.1 - 1.8e-60 204.4 0.1 2.1e-60 204.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMG50081.1 - 5.2e-39 133.7 0.2 6.2e-39 133.5 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG50081.1 - 1e-11 45.1 0.2 1.5e-11 44.5 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMG50081.1 - 1.8e-06 27.6 0.6 7.7e-06 25.5 0.6 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMG50081.1 - 0.00027 20.5 0.9 0.00037 20.0 0.2 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EMG50081.1 - 0.0057 16.6 0.3 0.0092 15.9 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMG50081.1 - 0.0061 15.6 0.2 0.0082 15.2 0.2 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EMG50081.1 - 0.0072 16.6 0.1 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 EMG50081.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 EMG50081.1 - 0.27 10.6 0.8 1 8.7 0.7 1.9 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_clus PF00172.18 EMG50082.1 - 3.1e-07 30.4 7.1 6.6e-07 29.3 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexokinase_1 PF00349.21 EMG50084.1 - 1.3e-69 234.1 0.0 1.9e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EMG50084.1 - 2.9e-68 229.9 0.0 4e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Ferric_reduct PF01794.19 EMG50085.1 - 1.7e-25 89.5 20.0 3.8e-25 88.4 17.6 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EMG50085.1 - 3.7e-24 84.9 0.2 8.5e-24 83.7 0.2 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EMG50085.1 - 4.3e-24 85.4 0.0 6.5e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain A_amylase_inhib PF01356.19 EMG50085.1 - 0.05 13.6 0.4 0.15 12.1 0.4 1.8 1 0 0 1 1 1 0 Alpha amylase inhibitor MWFE PF15879.5 EMG50085.1 - 4.4 7.5 5.3 1.5 9.0 0.5 2.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit p450 PF00067.22 EMG50086.1 - 2.4e-63 214.5 0.0 3.3e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.23 EMG50087.1 - 4.7e-69 232.7 0.0 1.2e-68 231.5 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMG50087.1 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG50087.1 - 1.5e-06 28.3 4.3 2.5e-06 27.6 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Cob_adeno_trans PF01923.18 EMG50087.1 - 0.058 13.5 2.4 0.21 11.7 2.4 1.9 1 0 0 1 1 1 0 Cobalamin adenosyltransferase CHZ PF09649.10 EMG50088.1 - 7.2e-20 70.2 1.7 7.2e-20 70.2 1.7 3.3 4 2 1 5 5 5 1 Histone chaperone domain CHZ MCM_bind PF09739.9 EMG50088.1 - 5.2 5.4 12.4 7.2 4.9 12.4 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Cyclin PF08613.11 EMG50089.1 - 4.4e-07 30.4 0.0 8.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin LSM PF01423.22 EMG50090.1 - 2.3e-19 68.9 2.3 3.4e-19 68.3 1.1 1.8 1 1 1 2 2 2 1 LSM domain Ras PF00071.22 EMG50091.1 - 1.2e-58 197.3 0.1 1.4e-58 197.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG50091.1 - 1.3e-34 119.0 0.1 1.8e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG50091.1 - 6.7e-12 45.2 0.0 8.6e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMG50091.1 - 2.6e-07 30.7 0.0 4.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMG50091.1 - 0.0032 17.4 0.5 0.024 14.5 0.1 2.0 1 1 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 EMG50091.1 - 0.0055 16.1 0.0 0.0088 15.4 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EMG50091.1 - 0.0062 16.9 0.0 0.01 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 EMG50091.1 - 0.0067 15.7 0.0 0.012 14.8 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 EMG50091.1 - 0.0069 16.7 0.1 0.031 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMG50091.1 - 0.014 15.9 0.0 0.023 15.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EMG50091.1 - 0.018 14.8 0.0 0.035 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EMG50091.1 - 0.018 14.5 0.0 0.094 12.2 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EMG50091.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF1128 PF06569.11 EMG50091.1 - 0.079 13.0 0.1 0.079 13.0 0.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1128) AAA_18 PF13238.6 EMG50091.1 - 0.082 13.5 0.1 0.39 11.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 EMG50091.1 - 0.082 12.8 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.18 EMG50091.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 EMG50091.1 - 0.12 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EMG50091.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 EMG50091.1 - 0.13 11.4 0.0 0.29 10.2 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain TniB PF05621.11 EMG50091.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF4407 PF14362.6 EMG50092.1 - 5.8 6.2 12.6 8.6 5.6 12.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TPP_enzyme_N PF02776.18 EMG50093.1 - 3.4e-20 72.4 0.0 6.2e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMG50093.1 - 1.6e-12 47.5 0.0 5.8e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMG50093.1 - 1e-07 31.8 0.0 2.8e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF1242 PF06842.12 EMG50094.1 - 9.4e-19 66.9 0.9 1.2e-18 66.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) UTP25 PF06862.12 EMG50095.1 - 6.9e-204 678.0 13.9 1e-203 677.4 13.9 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_C PF00271.31 EMG50095.1 - 2.9e-05 24.4 0.2 0.002 18.4 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain NINJA_B PF16136.5 EMG50095.1 - 0.087 13.2 3.7 0.24 11.8 3.7 1.7 1 0 0 1 1 1 0 Putative nuclear localisation signal DEAD PF00270.29 EMG50095.1 - 0.15 11.8 0.2 2.9 7.6 0.2 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase P16-Arc PF04699.14 EMG50096.1 - 6.1e-47 159.8 0.0 6.8e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) RPN13_C PF16550.5 EMG50096.1 - 0.11 12.7 0.1 0.29 11.3 0.1 1.8 1 1 1 2 2 2 0 UCH-binding domain Methyltransf_28 PF02636.17 EMG50097.1 - 1.4e-84 283.8 0.0 1.8e-84 283.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DEP PF00610.21 EMG50098.1 - 2.5e-15 56.3 0.0 5.8e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 EMG50098.1 - 3.4e-13 49.7 1.2 1.7e-12 47.4 1.2 2.2 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EMG50098.1 - 3.4e-08 33.7 1.0 8.6e-07 29.2 0.0 3.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Lectin_leg-like PF03388.13 EMG50099.1 - 4.7e-16 58.8 0.6 7.4e-16 58.2 0.6 1.2 1 0 0 1 1 1 1 Legume-like lectin family NPCBM PF08305.11 EMG50099.1 - 0.1 12.8 0.2 1.9 8.7 0.2 2.7 1 1 1 2 2 2 0 NPCBM/NEW2 domain DUF2730 PF10805.8 EMG50099.1 - 0.51 10.4 4.8 6.1 7.0 0.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Spectrin PF00435.21 EMG50099.1 - 1.1 9.7 10.6 0.67 10.5 3.3 2.7 2 1 0 2 2 2 0 Spectrin repeat DUF745 PF05335.13 EMG50099.1 - 3.8 7.2 13.6 0.12 12.1 6.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) VPS11_C PF12451.8 EMG50099.1 - 6 7.2 5.7 2.9 8.2 2.0 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal WSC PF01822.19 EMG50100.1 - 1.3e-10 41.3 17.0 1.3e-10 41.3 17.0 3.2 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.10 EMG50100.1 - 0.0042 16.5 1.2 0.0042 16.5 1.2 3.1 3 0 0 3 3 3 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 EMG50100.1 - 0.011 15.6 0.0 0.011 15.6 0.0 3.6 2 1 1 3 3 3 0 TMEM154 protein family Syndecan PF01034.20 EMG50100.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Utp14 PF04615.13 EMG50100.1 - 0.059 12.0 7.4 0.073 11.6 7.4 1.1 1 0 0 1 1 1 0 Utp14 protein Otopetrin PF03189.13 EMG50100.1 - 0.77 8.5 3.5 1.2 7.8 3.5 1.3 1 0 0 1 1 1 0 Otopetrin Hamartin PF04388.12 EMG50100.1 - 4.1 6.0 36.3 6.3 5.3 36.3 1.4 1 0 0 1 1 1 0 Hamartin protein SDA1 PF05285.12 EMG50100.1 - 4.5 6.6 10.9 6.7 6.0 10.9 1.2 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.7 EMG50100.1 - 9.3 4.2 17.6 12 3.8 17.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EMP24_GP25L PF01105.24 EMG50101.1 - 2.4e-46 157.9 0.2 2.8e-46 157.7 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SNF2_N PF00176.23 EMG50102.1 - 5.8e-52 176.5 0.0 9.3e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMG50102.1 - 6.9e-18 65.0 0.3 1.7e-16 60.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG50102.1 - 4e-11 43.2 0.0 4e-11 43.2 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HHH_3 PF12836.7 EMG50102.1 - 0.078 13.2 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif GATase_5 PF13507.6 EMG50102.1 - 0.12 11.4 0.2 0.32 10.1 0.2 1.6 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ERAP1_C PF11838.8 EMG50103.1 - 1.5e-41 143.0 0.5 1.5e-41 143.0 0.5 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EMG50103.1 - 3.4e-39 134.7 2.2 3.4e-39 134.7 2.2 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EMG50103.1 - 8.6e-21 75.0 3.4 8.6e-21 75.0 3.4 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain SCFA_trans PF02667.14 EMG50103.1 - 0.027 13.5 0.1 0.047 12.7 0.1 1.3 1 0 0 1 1 1 0 Short chain fatty acid transporter Thg1C PF14413.6 EMG50103.1 - 0.051 13.7 1.2 0.22 11.7 0.1 2.5 2 0 0 2 2 2 0 Thg1 C terminal domain Chor_lyase PF04345.13 EMG50103.1 - 0.099 12.3 0.3 0.47 10.1 0.1 2.1 2 0 0 2 2 2 0 Chorismate lyase PI3_PI4_kinase PF00454.27 EMG50104.1 - 5.1e-53 180.4 3.6 2.1e-51 175.1 0.0 4.4 4 0 0 4 4 4 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EMG50104.1 - 2e-31 109.2 5.3 2e-31 109.2 5.3 2.9 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EMG50104.1 - 1.2e-10 41.0 0.0 3.5e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 FATC domain PKcGMP_CC PF16808.5 EMG50104.1 - 0.025 14.4 0.8 0.077 12.9 0.8 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ALMS_motif PF15309.6 EMG50104.1 - 0.76 10.2 10.8 0.24 11.9 7.6 1.8 2 0 0 2 2 2 0 ALMS motif YabA PF06156.13 EMG50104.1 - 4.6 7.9 8.1 3.2 8.4 4.7 2.7 2 0 0 2 2 2 0 Initiation control protein YabA DUF2935 PF11155.8 EMG50105.1 - 0.027 14.8 0.3 0.072 13.4 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) RRM_1 PF00076.22 EMG50106.1 - 6.2e-28 96.4 5.7 2e-10 40.3 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMG50106.1 - 3.5e-12 46.0 0.1 0.031 14.1 0.0 4.6 4 0 0 4 4 4 4 Occluded RNA-recognition motif DUF4523 PF15023.6 EMG50106.1 - 0.00032 20.6 0.0 0.079 12.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 EMG50106.1 - 0.0013 18.7 0.6 4 7.5 0.2 3.8 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 EMG50106.1 - 0.034 13.9 0.1 0.74 9.6 0.0 2.9 3 1 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EMG50106.1 - 0.092 12.9 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 RNA recognition motif Use1 PF09753.9 EMG50107.1 - 6.1e-09 36.0 4.6 8.3e-09 35.5 4.6 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Exonuc_VII_L PF02601.15 EMG50107.1 - 0.00083 19.0 1.5 0.0011 18.7 1.5 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Peptidase_C98 PF15499.6 EMG50107.1 - 0.062 12.8 0.8 0.1 12.0 0.5 1.6 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase TBCC_N PF16752.5 EMG50107.1 - 0.35 11.3 7.0 0.38 11.2 0.1 2.9 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain HD_3 PF13023.6 EMG50108.1 - 0.0043 17.0 0.1 0.0067 16.4 0.1 1.3 1 0 0 1 1 1 1 HD domain ABC_membrane PF00664.23 EMG50110.1 - 2.4e-39 135.6 18.2 3.6e-39 135.1 18.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMG50110.1 - 2.2e-35 122.2 0.4 5.3e-35 120.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EMG50110.1 - 7.1e-08 32.2 0.7 5.7e-05 22.6 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMG50110.1 - 0.0013 18.7 0.1 0.044 13.6 0.1 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMG50110.1 - 0.0014 18.9 0.2 0.014 15.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMG50110.1 - 0.0021 18.5 0.1 0.0058 17.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EMG50110.1 - 0.0029 17.3 0.1 0.0078 15.9 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.7 EMG50110.1 - 0.012 14.5 0.2 0.38 9.6 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain DEAD PF00270.29 EMG50110.1 - 0.012 15.4 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Utp11 PF03998.13 EMG50110.1 - 0.023 14.6 0.4 0.039 13.9 0.4 1.4 1 0 0 1 1 1 0 Utp11 protein AAA PF00004.29 EMG50110.1 - 0.049 14.1 0.0 0.43 11.0 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EMG50110.1 - 0.05 13.3 0.1 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EMG50110.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EMG50110.1 - 0.075 13.1 0.1 1.1 9.3 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 EMG50110.1 - 0.13 12.4 0.0 0.47 10.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain SbcCD_C PF13558.6 EMG50110.1 - 0.16 12.2 0.1 1.5 9.1 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Aminotran_5 PF00266.19 EMG50111.1 - 2.2e-30 105.9 0.0 2.6e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 EMG50111.1 - 0.00084 19.4 0.6 0.0053 16.8 0.1 2.2 2 0 0 2 2 2 1 B12 binding domain Apt1 PF10351.9 EMG50112.1 - 0.00053 19.0 4.5 0.00053 19.0 4.5 2.1 2 0 0 2 2 2 1 Golgi-body localisation protein domain PRCC PF10253.9 EMG50112.1 - 0.014 16.2 11.7 0.033 15.0 11.7 1.7 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SLC12 PF03522.15 EMG50112.1 - 1.2 8.0 7.8 2.3 7.2 6.2 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Alba PF01918.21 EMG50113.1 - 4.2e-10 39.3 0.6 7e-10 38.6 0.6 1.3 1 0 0 1 1 1 1 Alba COX6B PF02297.17 EMG50114.1 - 1.1e-17 64.0 1.5 1.4e-17 63.7 1.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EMG50114.1 - 0.0062 16.5 0.7 0.0089 16.0 0.7 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NFACT-R_1 PF05670.13 EMG50115.1 - 1.8e-35 121.8 0.3 3.6e-35 120.9 0.3 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain LMBR1 PF04791.16 EMG50115.1 - 2.9 6.7 5.9 3.1 6.6 5.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_S2 PF00318.20 EMG50116.1 - 6.4e-61 205.3 0.8 6.4e-61 205.3 0.8 2.6 3 1 0 3 3 3 1 Ribosomal protein S2 CCD48 PF15799.5 EMG50116.1 - 0.01 14.2 4.4 0.25 9.6 2.5 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 48 CS PF04969.16 EMG50117.1 - 1.5e-05 25.9 0.1 3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 CS domain LRR_4 PF12799.7 EMG50118.1 - 4.3e-09 36.5 28.4 0.00057 20.2 0.5 8.1 7 1 2 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG50118.1 - 2.2e-07 30.5 24.8 0.0013 18.5 1.3 6.3 4 2 1 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 EMG50118.1 - 0.044 13.9 11.0 0.61 10.3 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich repeat F-box PF00646.33 EMG50118.1 - 0.1 12.5 0.2 0.29 11.1 0.2 1.8 1 0 0 1 1 1 0 F-box domain LRR_1 PF00560.33 EMG50118.1 - 2.8 8.9 23.7 22 6.1 0.4 8.6 8 2 0 8 8 8 0 Leucine Rich Repeat PALP PF00291.25 EMG50119.1 - 3.2e-63 213.9 0.0 3.7e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Keratin_matx PF04579.12 EMG50119.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Keratin, high-sulphur matrix protein Stealth_CR4 PF17103.5 EMG50119.1 - 0.83 9.6 0.0 0.83 9.6 0.0 2.6 4 0 0 4 4 4 0 Stealth protein CR4, conserved region 4 PEX11 PF05648.14 EMG50120.1 - 4e-07 29.7 1.7 0.017 14.6 0.5 2.6 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Fumble PF03630.14 EMG50121.1 - 6.4e-127 423.3 3.7 8.1e-127 423.0 3.7 1.1 1 0 0 1 1 1 1 Fumble DUF4978 PF16349.5 EMG50121.1 - 0.017 14.8 1.2 3.8 7.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4978) NOA36 PF06524.12 EMG50121.1 - 6.6 6.0 6.4 10 5.3 6.4 1.2 1 0 0 1 1 1 0 NOA36 protein NGP1NT PF08153.12 EMG50122.1 - 1.4e-53 180.5 1.2 2.6e-53 179.6 1.2 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EMG50122.1 - 4.7e-17 62.1 0.0 2.9e-13 49.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EMG50122.1 - 0.00011 21.8 0.0 0.00044 19.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMG50122.1 - 0.0016 18.4 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EMG50122.1 - 0.0024 17.4 0.1 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.23 EMG50122.1 - 0.0028 17.7 0.1 0.87 9.6 0.0 3.6 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 EMG50122.1 - 0.0085 15.7 0.0 0.84 9.1 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ndc1_Nup PF09531.10 EMG50123.1 - 1.3 7.7 25.9 0.32 9.6 22.9 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup CDC50 PF03381.15 EMG50124.1 - 9.9e-93 310.7 3.2 1.2e-92 310.4 3.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family tRNA-synt_2c PF01411.19 EMG50125.1 - 5.6e-227 754.6 0.3 8e-227 754.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EMG50125.1 - 1.8e-18 66.4 0.2 4.7e-18 65.0 0.2 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EMG50125.1 - 3.8e-11 43.6 1.6 1.3e-10 41.8 1.6 2.0 1 0 0 1 1 1 1 DHHA1 domain DUF4363 PF14276.6 EMG50125.1 - 0.0052 16.9 2.4 0.016 15.3 2.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4363) DKNYY PF13644.6 EMG50125.1 - 5.2 7.8 7.3 2.4 9.0 2.1 3.0 3 1 0 3 3 3 0 DKNYY family DUF1992 PF09350.10 EMG50126.1 - 6.2e-19 67.9 0.3 3.1e-18 65.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) p450 PF00067.22 EMG50127.1 - 7.7e-64 216.1 0.0 9.4e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LisH PF08513.11 EMG50128.1 - 1.5e-06 28.0 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 LisH LisH_2 PF16045.5 EMG50128.1 - 0.19 10.8 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 LisH SRP-alpha_N PF04086.13 EMG50128.1 - 0.56 10.1 17.4 0.79 9.6 17.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Glyco_transf_4 PF13439.6 EMG50129.1 - 3.5e-14 53.2 0.0 4.5e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EMG50129.1 - 7.7e-10 38.6 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 EMG50129.1 - 0.0013 18.9 1.1 0.12 12.4 0.3 2.5 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus WD40 PF00400.32 EMG50130.1 - 2.9e-19 69.1 4.3 0.0089 16.9 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50130.1 - 1.7e-10 41.1 0.0 3e-05 24.2 0.0 4.2 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMG50130.1 - 0.00055 18.7 0.4 0.004 15.9 0.1 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EMG50130.1 - 0.00062 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain CNH PF00780.22 EMG50130.1 - 0.0094 15.6 0.0 0.18 11.4 0.0 2.1 1 1 0 1 1 1 1 CNH domain eIF2A PF08662.11 EMG50130.1 - 0.048 13.5 0.2 0.52 10.2 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EMG50130.1 - 0.071 12.1 0.0 1.1 8.1 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Voltage_CLC PF00654.20 EMG50131.1 - 5.4e-76 256.1 14.4 7.3e-76 255.7 14.4 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel His_Phos_1 PF00300.22 EMG50132.1 - 2.8e-05 23.9 0.3 0.0001 22.1 0.3 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-RAG1 PF10426.9 EMG50132.1 - 0.014 15.6 0.3 0.029 14.5 0.3 1.5 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain FF PF01846.19 EMG50132.1 - 3.6 7.8 5.3 25 5.1 0.1 3.2 4 1 0 4 4 4 0 FF domain Spc7 PF08317.11 EMG50133.1 - 2.6e-62 210.5 16.8 2.6e-62 210.5 16.8 2.7 4 0 0 4 4 4 1 Spc7 kinetochore protein DegS PF05384.11 EMG50133.1 - 1.3 8.5 14.1 0.37 10.3 0.6 3.5 3 0 0 3 3 3 0 Sensor protein DegS FapA PF03961.13 EMG50133.1 - 6 5.4 12.9 2.4 6.7 9.3 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF641 PF04859.12 EMG50133.1 - 9.3 6.6 10.9 5 7.5 7.2 2.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Aa_trans PF01490.18 EMG50134.1 - 1.1e-97 327.4 25.0 1.2e-97 327.2 25.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Motile_Sperm PF00635.26 EMG50135.1 - 3e-24 85.0 0.2 9.7e-24 83.3 0.0 1.9 1 1 0 1 1 1 1 MSP (Major sperm protein) domain GHMP_kinases_N PF00288.26 EMG50135.1 - 0.029 14.6 0.9 0.055 13.7 0.9 1.5 1 0 0 1 1 1 0 GHMP kinases N terminal domain RIFIN PF02009.16 EMG50135.1 - 0.07 13.0 0.5 0.17 11.8 0.3 1.7 1 1 1 2 2 2 0 Rifin Ndc1_Nup PF09531.10 EMG50135.1 - 0.19 10.4 13.8 0.27 9.9 13.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NrsF PF06532.11 EMG50135.1 - 0.89 9.2 6.7 0.19 11.4 2.9 1.7 2 0 0 2 2 2 0 Negative regulator of sigma F Med15 PF09606.10 EMG50135.1 - 1.4 7.5 37.7 1.9 7.1 37.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ABC2_membrane_2 PF12679.7 EMG50135.1 - 1.7 7.8 4.0 12 5.1 0.0 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein PAT1 PF09770.9 EMG50135.1 - 1.9 6.7 21.8 2.4 6.3 21.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med11 PF10280.9 EMG50135.1 - 9.6 6.7 12.9 1.1 9.7 3.7 2.5 2 0 0 2 2 2 0 Mediator complex protein Peptidase_M24 PF00557.24 EMG50136.1 - 1.2e-41 142.7 0.4 1.5e-41 142.4 0.4 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 RP-C_C PF11800.8 EMG50136.1 - 0.35 10.9 1.7 0.58 10.2 1.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CCDC106 PF15794.5 EMG50136.1 - 0.97 9.1 7.4 1.8 8.2 7.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 EMG50136.1 - 3.1 6.0 7.8 4.6 5.4 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein PGA2 PF07543.12 EMG50136.1 - 6.7 6.7 11.9 0.34 10.9 6.3 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 RNA_pol_Rpc4 PF05132.14 EMG50136.1 - 9.7 6.6 8.5 17 5.8 8.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Chromo_2 PF18704.1 EMG50137.1 - 0.0097 16.2 0.1 0.0097 16.2 0.1 2.0 2 0 0 2 2 2 1 Chromatin organization modifier domain 2 DUF2826 PF11442.8 EMG50137.1 - 0.033 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) TACC_C PF05010.14 EMG50137.1 - 0.1 12.3 1.1 0.17 11.6 1.1 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HELP PF03451.14 EMG50137.1 - 0.13 12.1 0.2 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 HELP motif DUF4467 PF14729.6 EMG50137.1 - 7.5 7.0 11.9 3.5 8.0 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) ALG3 PF05208.13 EMG50138.1 - 4.4e-120 401.4 26.6 5.9e-120 401.0 26.6 1.2 1 0 0 1 1 1 1 ALG3 protein zf-C4H2 PF10146.9 EMG50141.1 - 0.0084 16.4 0.8 0.013 15.8 0.8 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein CspB_prodomain PF18425.1 EMG50141.1 - 0.07 13.1 0.3 0.19 11.7 0.2 1.9 1 1 0 1 1 1 0 Csp protease B prodomain DUF3106 PF11304.8 EMG50142.1 - 1 9.9 10.6 19 5.8 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3106) DUF1289 PF06945.13 EMG50142.1 - 6.1 6.7 10.1 15 5.5 0.1 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1289) PEX11 PF05648.14 EMG50143.1 - 1.5e-70 237.2 0.5 1.6e-70 237.0 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF1911 PF08929.10 EMG50143.1 - 0.074 13.9 0.1 4.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) Mrr_cat_2 PF13156.6 EMG50143.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease NTF2 PF02136.20 EMG50145.1 - 1.1e-14 55.0 0.5 1.1e-14 55.0 0.5 1.7 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RR_TM4-6 PF06459.12 EMG50145.1 - 5.7 6.7 26.6 9.4 6.0 26.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UQ_con PF00179.26 EMG50146.1 - 1.7e-45 154.1 0.0 2.1e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EMG50146.1 - 9.8e-19 66.9 0.1 1.5e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EMG50146.1 - 0.0018 18.0 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMG50146.1 - 0.031 14.6 0.1 0.06 13.6 0.1 1.6 1 1 0 1 1 1 0 RWD domain UBA PF00627.31 EMG50146.1 - 0.038 13.9 0.7 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain DUF1421 PF07223.11 EMG50146.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) FeoA PF04023.14 EMG50146.1 - 0.2 11.9 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 FeoA domain Not1 PF04054.15 EMG50147.1 - 1.1e-137 458.9 0.1 1.1e-137 458.9 0.1 2.4 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EMG50147.1 - 6.2e-83 277.6 4.3 2.1e-82 275.9 4.3 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_HEAT_N PF16419.5 EMG50147.1 - 8.9e-78 261.1 5.6 8.9e-78 261.1 5.6 3.3 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_TTP_bind PF16417.5 EMG50147.1 - 9.2e-48 161.9 1.6 9.2e-48 161.9 1.6 4.6 4 1 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 EMG50147.1 - 9.5e-32 109.9 1.9 9.5e-32 109.9 1.9 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 EMG50147.1 - 4.2e-21 75.6 0.1 4.2e-21 75.6 0.1 3.5 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat TFIIA PF03153.13 EMG50147.1 - 0.086 12.8 44.7 0.016 15.3 17.8 2.7 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit SCA7 PF08313.12 EMG50148.1 - 2e-07 30.8 0.0 2e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain Serinc PF03348.15 EMG50148.1 - 1.8 7.4 5.2 3 6.7 5.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) EIF4E-T PF10477.9 EMG50148.1 - 2.3 6.9 28.1 3.6 6.3 28.1 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Pkinase PF00069.25 EMG50149.1 - 1.4e-60 204.9 0.1 2e-60 204.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50149.1 - 2.9e-37 128.4 0.0 3.8e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG50149.1 - 0.00067 18.5 0.3 0.0008 18.3 0.3 1.4 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EMG50149.1 - 0.0011 18.7 0.6 0.31 10.6 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EMG50149.1 - 0.0024 17.3 0.0 0.012 15.0 0.0 1.9 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EMG50149.1 - 0.037 13.6 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EMG50149.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Radical_SAM PF04055.21 EMG50150.1 - 7.9e-23 81.7 0.0 2.4e-22 80.1 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 EMG50150.1 - 1.3e-21 76.7 0.0 2.9e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 EMG50150.1 - 1.9e-16 60.6 0.0 6.4e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin ALG11_N PF15924.5 EMG50152.1 - 3.4e-69 233.1 0.1 5.2e-69 232.5 0.1 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EMG50152.1 - 1.9e-17 63.3 0.0 3.5e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Coatomer_WDAD PF04053.14 EMG50153.1 - 9.4e-177 588.5 3.7 9.4e-177 588.5 3.7 1.7 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EMG50153.1 - 5.2e-37 125.2 7.3 6.1e-07 30.0 0.0 8.8 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50153.1 - 3.2e-10 40.2 0.6 6.1 7.2 0.1 6.5 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMG50153.1 - 1.4e-05 24.0 3.8 0.0056 15.4 0.0 4.6 1 1 3 5 5 5 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EMG50153.1 - 6.2e-05 23.0 0.3 0.2 11.7 0.0 4.9 3 2 3 6 6 6 1 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 EMG50153.1 - 0.00066 19.9 0.3 0.0025 18.1 0.1 2.1 2 0 0 2 2 2 1 C terminal of Calcineurin-like phosphoesterase SBP56 PF05694.11 EMG50153.1 - 0.032 13.0 0.0 0.46 9.2 0.0 2.4 2 0 0 2 2 2 0 56kDa selenium binding protein (SBP56) NAD_binding_11 PF14833.6 EMG50153.1 - 0.059 13.6 0.0 15 5.9 0.0 2.5 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PQQ PF01011.21 EMG50153.1 - 0.18 11.8 1.8 1.8 8.7 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat FtsJ PF01728.19 EMG50154.1 - 1.1e-22 81.0 0.0 1.6e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CP_ATPgrasp_1 PF04174.13 EMG50154.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Ribosomal_L1 PF00687.21 EMG50155.1 - 1.7e-42 145.5 1.4 2.1e-42 145.2 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Arf PF00025.21 EMG50156.1 - 1.6e-58 197.0 2.1 1.3e-55 187.6 0.0 3.6 3 1 1 4 4 4 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMG50156.1 - 4.4e-24 84.7 0.1 1.5e-14 54.1 0.0 3.7 3 1 0 3 3 3 2 50S ribosome-binding GTPase G-alpha PF00503.20 EMG50156.1 - 2.2e-10 40.2 0.4 8.2e-07 28.5 0.0 3.8 3 1 1 4 4 4 2 G-protein alpha subunit Roc PF08477.13 EMG50156.1 - 1.1e-09 38.5 0.1 2.2e-06 27.9 0.0 3.8 4 0 0 4 4 4 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EMG50156.1 - 1.8e-09 37.3 0.0 2.5e-08 33.6 0.0 2.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EMG50156.1 - 3e-08 33.4 2.0 1e-06 28.5 0.0 3.4 4 0 0 4 4 4 1 Ras family FeoB_N PF02421.18 EMG50156.1 - 2.8e-07 30.2 2.8 2e-05 24.2 0.0 3.8 5 0 0 5 5 5 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMG50156.1 - 1.7e-06 28.1 2.1 0.0036 17.2 0.0 4.0 3 1 0 4 4 4 1 RsgA GTPase Gtr1_RagA PF04670.12 EMG50156.1 - 6e-05 22.5 0.0 0.0032 16.8 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 EMG50156.1 - 0.01 15.9 0.0 0.079 13.0 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 EMG50156.1 - 0.013 16.1 1.8 7.2 7.2 0.0 4.4 4 0 0 4 4 4 0 AAA domain MobB PF03205.14 EMG50156.1 - 0.036 13.9 0.1 14 5.6 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EMG50156.1 - 0.039 13.5 1.8 1.8 8.2 0.0 3.7 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 EMG50156.1 - 0.042 13.2 1.4 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 AIG1 family zf_C2H2_13 PF18508.1 EMG50157.1 - 0.0019 17.8 0.2 0.0041 16.7 0.2 1.5 1 0 0 1 1 1 1 Zinc finger domain OrsD PF12013.8 EMG50157.1 - 0.0033 17.8 1.8 0.0071 16.8 1.8 1.5 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Elongin_A PF06881.11 EMG50157.1 - 0.0056 17.2 1.1 0.0056 17.2 1.1 1.5 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Methyltransf_32 PF13679.6 EMG50157.1 - 0.0078 16.2 0.4 0.011 15.7 0.4 1.2 1 0 0 1 1 1 1 Methyltransferase domain Sgf11 PF08209.11 EMG50157.1 - 0.012 15.2 0.2 0.019 14.5 0.2 1.3 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Miff PF05644.11 EMG50157.1 - 0.018 14.7 2.2 0.022 14.4 2.2 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF2256 PF10013.9 EMG50157.1 - 0.09 12.9 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3128 PF11326.8 EMG50157.1 - 0.11 12.9 2.3 0.21 12.0 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Rsm1 PF08600.10 EMG50157.1 - 0.13 12.5 0.2 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 Rsm1-like DUF420 PF04238.12 EMG50158.1 - 0.021 15.1 0.6 0.031 14.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF420) GCV_T PF01571.21 EMG50159.1 - 4.6e-84 281.8 0.0 5.5e-84 281.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EMG50159.1 - 6.3e-15 54.9 0.0 1.4e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 EMG50159.1 - 4.8e-07 30.0 0.0 0.0015 18.7 0.0 2.8 2 1 1 3 3 3 2 Sarcosine oxidase, gamma subunit family S-layer PF07752.11 EMG50159.1 - 0.069 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 S-layer protein TPR_6 PF13174.6 EMG50159.1 - 0.12 13.0 0.3 3.8 8.3 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M41 PF01434.18 EMG50160.1 - 0.0011 18.8 0.3 0.0015 18.4 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M41 Herpes_UL25 PF01499.16 EMG50161.1 - 0.47 8.9 12.0 0.6 8.6 12.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF4045 PF13254.6 EMG50161.1 - 6.5 6.3 24.0 8.5 5.9 24.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) ANAPC_CDC26 PF10471.9 EMG50162.1 - 4.6e-16 59.4 17.1 6.2e-16 59.0 17.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 PBP_dimer PF03717.15 EMG50162.1 - 0.011 16.1 7.9 0.012 16.0 7.9 1.0 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain OmpH PF03938.14 EMG50162.1 - 0.015 15.6 11.6 0.017 15.4 11.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GTA_holin_3TM PF11351.8 EMG50162.1 - 0.87 10.1 3.4 1.3 9.6 3.4 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release LMBR1 PF04791.16 EMG50162.1 - 7.5 5.3 6.2 8.2 5.2 6.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein p450 PF00067.22 EMG50163.1 - 1.1e-59 202.4 0.0 1.5e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YlbE PF14003.6 EMG50163.1 - 0.11 13.0 0.0 0.94 10.0 0.0 2.3 2 0 0 2 2 2 0 YlbE-like protein p450 PF00067.22 EMG50164.1 - 4.7e-60 203.6 0.0 6.3e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YlbE PF14003.6 EMG50164.1 - 0.12 12.8 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 YlbE-like protein HJURP_mid PF12346.8 EMG50166.1 - 3.8 8.0 6.1 4.8 7.7 0.2 2.6 1 1 1 2 2 2 0 Holliday junction recognition protein-associated repeat TRP PF06011.12 EMG50167.1 - 9.8e-153 508.9 37.7 1.6e-152 508.2 37.7 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EMG50167.1 - 3.2e-38 131.2 1.5 5.3e-38 130.5 1.5 1.4 1 0 0 1 1 1 1 ML-like domain DUF4834 PF16118.5 EMG50167.1 - 1.4 9.9 6.3 48 5.0 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) KilA-N PF04383.13 EMG50168.1 - 1.4e-05 24.9 1.5 0.00023 21.0 0.0 3.1 2 1 0 2 2 2 1 KilA-N domain zf-C2H2 PF00096.26 EMG50170.1 - 4.3e-10 39.5 16.3 0.0014 19.0 2.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG50170.1 - 9.9e-07 29.1 14.2 0.004 17.9 0.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMG50170.1 - 0.00032 20.6 0.7 0.2 11.7 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMG50170.1 - 0.0011 19.3 0.5 0.0011 19.3 0.5 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 EMG50170.1 - 0.052 13.9 0.9 0.11 12.8 0.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 EMG50170.1 - 0.086 13.1 0.1 0.086 13.1 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF4763 PF15960.5 EMG50170.1 - 0.29 10.4 9.3 0.063 12.6 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) zf-TRAF PF02176.18 EMG50170.1 - 2.1 9.1 5.9 0.75 10.5 2.7 1.9 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2 PF00096.26 EMG50171.1 - 5.5e-09 36.0 15.5 0.00013 22.3 2.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 EMG50171.1 - 5.5e-07 29.8 9.3 0.0082 16.5 0.5 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EMG50171.1 - 3.3e-06 27.5 13.9 0.0096 16.7 2.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMG50171.1 - 3.4e-06 27.2 16.4 2e-05 24.8 6.7 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EMG50171.1 - 0.00011 22.3 8.8 0.045 14.1 1.4 3.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EMG50171.1 - 0.0013 18.6 9.9 0.0013 18.6 2.0 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 EMG50171.1 - 0.018 15.4 4.2 0.041 14.2 4.2 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF3246 PF11596.8 EMG50171.1 - 0.064 12.7 8.3 0.22 10.9 8.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) zf-MYST PF17772.1 EMG50171.1 - 2.2 8.0 4.0 0.92 9.2 0.3 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain DUF4448 PF14610.6 EMG50172.1 - 1.5e-05 24.9 0.0 4.9e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Kelch_6 PF13964.6 EMG50172.1 - 0.00063 19.9 1.5 0.039 14.3 0.1 3.5 3 0 0 3 3 3 1 Kelch motif SKG6 PF08693.10 EMG50172.1 - 0.00076 18.8 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_3 PF13415.6 EMG50172.1 - 0.0008 19.6 0.1 0.0059 16.9 0.1 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.6 EMG50172.1 - 0.0061 16.5 5.6 0.06 13.4 0.1 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain PspB PF06667.12 EMG50172.1 - 0.0076 16.3 0.1 0.021 14.9 0.1 1.7 1 0 0 1 1 1 1 Phage shock protein B Orf78 PF06024.12 EMG50172.1 - 0.034 14.4 0.0 0.034 14.4 0.0 2.7 3 0 0 3 3 3 0 Orf78 (ac78) FixQ PF05545.11 EMG50172.1 - 0.053 13.5 0.4 0.12 12.3 0.4 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ SIT PF15330.6 EMG50172.1 - 0.12 12.8 0.0 0.5 10.8 0.0 2.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT 2-oxoacid_dh PF00198.23 EMG50173.1 - 1e-80 270.5 0.1 1.9e-80 269.7 0.1 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EMG50173.1 - 2.6e-17 62.4 3.5 5e-17 61.5 3.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EMG50173.1 - 0.00016 21.4 0.5 0.013 15.3 0.3 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 EMG50173.1 - 0.00037 20.4 0.2 0.00078 19.3 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 EMG50173.1 - 0.0089 16.7 1.0 0.37 11.5 0.3 2.6 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 EMG50173.1 - 0.044 13.7 0.4 0.21 11.6 0.4 2.1 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain CDC27 PF09507.10 EMG50173.1 - 0.21 10.9 11.0 0.3 10.4 11.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4674 PF15719.5 EMG50173.1 - 0.68 9.9 5.3 1.2 9.1 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) MRP-L47 PF06984.13 EMG50174.1 - 1.6e-15 57.0 0.6 2.5e-15 56.3 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Selenoprotein_S PF06936.11 EMG50174.1 - 0.16 11.7 1.3 0.27 11.0 1.3 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) AIM5 PF17050.5 EMG50175.1 - 5e-16 59.3 0.1 6.9e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 adh_short PF00106.25 EMG50176.1 - 8.7e-28 97.1 0.0 1.1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG50176.1 - 7.6e-17 61.6 0.0 9.8e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG50176.1 - 3.8e-07 30.2 0.0 6.5e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EMG50176.1 - 0.0048 16.2 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_tran_WecB PF03808.13 EMG50176.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Polysacc_synt_2 PF02719.15 EMG50176.1 - 0.033 13.3 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 EMG50176.1 - 0.088 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ribosomal_L17 PF01196.19 EMG50177.1 - 2.3e-23 82.9 0.1 3.5e-23 82.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Mrpl_C PF18502.1 EMG50177.1 - 0.13 12.5 1.9 0.21 11.9 0.3 2.1 2 1 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Pyr_redox_2 PF07992.14 EMG50178.1 - 2.5e-70 237.0 6.5 2.5e-70 237.0 6.5 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EMG50178.1 - 7.9e-44 148.4 0.1 2e-43 147.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EMG50178.1 - 2.2e-19 69.8 11.5 7e-18 65.0 1.9 3.3 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMG50178.1 - 1.2e-12 47.7 7.6 1.9e-11 43.7 1.0 2.7 2 1 1 3 3 3 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EMG50178.1 - 1.5e-11 44.3 10.3 1.1e-10 41.5 0.6 3.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMG50178.1 - 2.5e-10 40.4 4.1 0.00033 20.8 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMG50178.1 - 4.3e-09 36.1 5.5 7.6e-06 25.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMG50178.1 - 3.6e-08 32.9 3.3 3.4e-05 23.2 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 EMG50178.1 - 2.3e-07 30.3 3.0 2.3e-07 30.3 3.0 3.2 3 1 1 4 4 4 1 FAD binding domain AlaDh_PNT_C PF01262.21 EMG50178.1 - 3.3e-07 29.8 2.2 0.0044 16.4 0.2 3.2 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EMG50178.1 - 6.2e-07 29.0 6.3 0.0073 15.6 0.2 3.3 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EMG50178.1 - 1.2e-06 27.5 11.6 0.00066 18.5 1.4 4.0 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 EMG50178.1 - 3.2e-05 23.3 0.4 0.025 13.7 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EMG50178.1 - 0.00015 20.9 0.5 0.063 12.3 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 EMG50178.1 - 0.00021 21.0 18.8 0.1 12.1 1.9 4.2 2 2 2 4 4 4 2 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EMG50178.1 - 0.0084 16.0 0.6 0.0084 16.0 0.6 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 EMG50178.1 - 0.035 14.6 0.1 2.3 8.8 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain Trp_halogenase PF04820.14 EMG50178.1 - 0.73 8.6 5.0 2.3 7.0 0.6 2.3 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 EMG50178.1 - 1.1 9.7 4.2 8 7.0 0.6 3.1 3 1 0 3 3 3 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EMG50178.1 - 1.4 8.4 4.5 0.44 10.1 0.2 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SNARE_assoc PF09335.11 EMG50179.1 - 4e-19 69.3 2.6 4e-19 69.3 2.6 3.0 3 1 0 3 3 3 1 SNARE associated Golgi protein Dsl1_C PF11989.8 EMG50180.1 - 2e-13 50.5 7.1 2e-13 50.5 7.1 3.4 3 1 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal BUD22 PF09073.10 EMG50180.1 - 0.002 17.6 6.6 0.0031 16.9 6.6 1.3 1 0 0 1 1 1 1 BUD22 GspH PF12019.8 EMG50180.1 - 0.18 12.2 0.6 0.38 11.2 0.2 1.7 2 0 0 2 2 2 0 Type II transport protein GspH Med27 PF11571.8 EMG50180.1 - 0.45 10.9 3.0 3 8.3 0.0 3.4 4 0 0 4 4 4 0 Mediator complex subunit 27 MID_MedPIWI PF18296.1 EMG50180.1 - 1.2 8.8 7.4 5.6 6.7 7.3 2.2 1 1 0 1 1 1 0 MID domain of medPIWI PBP1_TM PF14812.6 EMG50180.1 - 4.2 7.8 8.4 13 6.3 8.4 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PEX11 PF05648.14 EMG50181.1 - 0.00034 20.1 0.8 0.00045 19.8 0.5 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) NAD_binding_6 PF08030.12 EMG50182.1 - 7.5e-25 87.9 0.0 1.6e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMG50182.1 - 5.3e-22 78.0 0.0 1.3e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EMG50182.1 - 2.1e-20 73.1 17.1 2.1e-20 73.1 17.1 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Amidase PF01425.21 EMG50183.1 - 2.3e-99 333.4 0.0 3e-99 333.0 0.0 1.2 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 EMG50184.1 - 2.7e-28 98.9 16.7 2.7e-28 98.9 16.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M1_N PF17900.1 EMG50185.1 - 0.00071 19.8 0.3 0.91 9.7 0.4 3.0 1 1 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 EMG50185.1 - 0.0017 18.0 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Asp PF00026.23 EMG50186.1 - 7.8e-81 271.9 12.8 9.2e-81 271.7 12.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMG50186.1 - 2.3e-07 31.2 9.1 2.2e-06 28.0 6.7 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EMG50186.1 - 0.027 14.3 0.3 0.85 9.4 0.1 2.8 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EMG50186.1 - 0.21 12.2 2.5 6.5 7.4 0.5 3.7 3 2 0 3 3 3 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EMG50186.1 - 0.57 10.9 4.5 10 6.9 0.7 3.3 2 2 0 2 2 2 0 Aspartyl protease PI3_PI4_kinase PF00454.27 EMG50187.1 - 1.6e-42 146.1 0.0 2.8e-40 138.7 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EMG50187.1 - 4.5e-24 84.9 1.1 1.9e-23 82.8 0.2 2.4 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) eIF-6 PF01912.18 EMG50188.1 - 2.8e-82 274.9 0.6 3.5e-82 274.6 0.6 1.1 1 0 0 1 1 1 1 eIF-6 family GYF PF02213.16 EMG50189.1 - 1.1e-14 53.8 2.3 2.4e-14 52.7 2.3 1.6 1 0 0 1 1 1 1 GYF domain ORC5_C PF14630.6 EMG50190.1 - 1.7e-31 109.8 0.1 2.4e-31 109.3 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EMG50190.1 - 7.3e-15 55.8 0.0 1.1e-14 55.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMG50190.1 - 0.00011 22.5 0.0 0.00018 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EMG50190.1 - 0.00017 22.0 0.0 0.00029 21.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EMG50190.1 - 0.029 14.4 0.3 0.14 12.2 0.3 2.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMG50190.1 - 0.032 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cadherin_C PF01049.17 EMG50190.1 - 0.032 14.5 0.1 0.058 13.7 0.1 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic region AAA_33 PF13671.6 EMG50190.1 - 0.082 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMG50190.1 - 0.15 12.5 0.8 8.8 6.8 0.2 3.2 2 1 0 2 2 2 0 RNA helicase DUF2990 PF11693.8 EMG50190.1 - 0.19 11.9 0.3 3.7 7.8 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2990) RRM_1 PF00076.22 EMG50191.1 - 2.4e-08 33.7 0.0 5.6e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMG50191.1 - 0.00069 19.2 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC37_M PF08565.11 EMG50192.1 - 6.4e-45 151.9 5.0 1.4e-44 150.8 1.7 2.5 2 1 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 EMG50192.1 - 9.3e-44 149.5 4.5 9.3e-44 149.5 4.5 3.1 3 1 0 3 3 3 2 Cdc37 N terminal kinase binding Vpu PF00558.19 EMG50192.1 - 0.031 14.1 1.2 0.11 12.3 1.2 1.9 1 0 0 1 1 1 0 Vpu protein E2_bind PF08825.10 EMG50192.1 - 0.032 14.4 1.1 44 4.3 0.0 3.6 3 0 0 3 3 3 0 E2 binding domain EutQ PF06249.12 EMG50193.1 - 2.4e-11 43.6 0.0 2.8e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 EMG50193.1 - 6e-07 29.1 0.2 8.3e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EMG50193.1 - 0.00011 21.8 0.1 0.00018 21.1 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 EMG50193.1 - 0.002 17.9 0.0 0.0051 16.5 0.0 1.5 1 1 1 2 2 2 1 Cupin Pirin PF02678.16 EMG50193.1 - 0.033 14.2 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Pirin VPS9 PF02204.18 EMG50194.1 - 4.4e-29 100.8 0.4 9.4e-29 99.7 0.4 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EMG50194.1 - 8.7e-11 42.0 1.0 2.3e-10 40.6 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 EMG50194.1 - 3.8e-08 32.9 0.1 9.3e-08 31.6 0.1 1.7 1 0 0 1 1 1 1 CUE domain Fe-S_biosyn PF01521.20 EMG50195.1 - 5.5e-20 71.6 0.0 9.1e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.7 EMG50195.1 - 0.1 12.8 0.1 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) F-actin_cap_A PF01267.17 EMG50196.1 - 0.0063 16.0 0.3 0.0078 15.7 0.3 1.2 1 0 0 1 1 1 1 F-actin capping protein alpha subunit GFO_IDH_MocA PF01408.22 EMG50199.1 - 3.1e-18 66.8 0.3 1.8e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMG50199.1 - 7.5e-05 22.7 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Mfa2 PF08842.10 EMG50199.1 - 0.012 15.3 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 NTPase_1 PF03266.15 EMG50199.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NTPase TrmB PF01978.19 EMG50199.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TK PF00265.18 EMG50199.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 Thymidine kinase Sec20 PF03908.13 EMG50200.1 - 2.1e-35 120.5 2.9 2.1e-35 120.5 2.9 2.6 3 0 0 3 3 3 1 Sec20 Lyase_N PF09092.11 EMG50200.1 - 0.013 15.3 0.6 0.022 14.6 0.6 1.3 1 0 0 1 1 1 0 Lyase, N terminal MIT_C PF16565.5 EMG50200.1 - 6.3 6.8 11.1 0.14 12.1 1.4 2.5 3 0 0 3 3 3 0 Phospholipase D-like domain at C-terminus of MIT Exo_endo_phos PF03372.23 EMG50201.1 - 8.4e-21 74.6 0.0 1.6e-20 73.6 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Enkurin PF13864.6 EMG50201.1 - 2 8.9 6.3 1.3 9.5 0.3 2.7 3 0 0 3 3 3 0 Calmodulin-binding Mob1_phocein PF03637.17 EMG50202.1 - 1e-20 74.4 0.0 1.5e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family WAC_Acf1_DNA_bd PF10537.9 EMG50203.1 - 1.6e-36 124.9 0.6 6.7e-36 122.9 0.6 2.2 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 EMG50203.1 - 9.2e-15 54.7 0.0 2e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 EMG50203.1 - 3.6e-07 30.6 31.1 3.6e-07 30.6 31.1 5.8 3 2 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 EMG50203.1 - 6.6e-05 22.4 0.0 0.00017 21.1 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Spore_III_AB PF09548.10 EMG50203.1 - 0.19 11.8 1.5 0.93 9.6 1.5 2.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Ubiq_cyt_C_chap PF03981.12 EMG50205.1 - 5.1e-38 130.3 0.2 7.9e-38 129.7 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF4998 PF16389.5 EMG50205.1 - 0.058 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function SRP_TPR_like PF17004.5 EMG50206.1 - 6.6e-11 42.3 13.3 2.1e-10 40.7 7.2 3.7 3 1 0 3 3 3 1 Putative TPR-like repeat SRP72 PF08492.12 EMG50206.1 - 4.9e-06 26.9 4.2 4.9e-06 26.9 4.2 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.6 EMG50206.1 - 2.2e-05 24.7 0.2 0.31 11.4 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EMG50206.1 - 4.5e-05 23.8 1.0 0.026 15.1 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMG50206.1 - 0.0013 18.6 15.5 0.0066 16.5 0.7 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMG50206.1 - 0.0026 18.5 0.0 0.77 10.7 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMG50206.1 - 0.0031 17.4 2.2 0.67 10.1 0.3 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMG50206.1 - 0.0073 16.5 7.0 0.27 11.5 1.1 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.12 EMG50206.1 - 0.012 15.7 0.6 0.18 11.9 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF627) PPR PF01535.20 EMG50206.1 - 0.015 15.5 0.0 0.16 12.3 0.0 2.5 2 0 0 2 2 2 0 PPR repeat RPN7 PF10602.9 EMG50206.1 - 0.028 14.1 2.0 2.5 7.8 0.1 2.8 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_1 PF00515.28 EMG50206.1 - 0.039 13.8 6.8 0.53 10.2 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMG50206.1 - 0.095 13.2 2.7 6.3 7.4 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMG50206.1 - 0.11 13.2 0.1 0.27 11.9 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMG50206.1 - 2.6 8.5 14.5 26 5.4 0.4 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMG50206.1 - 5.1 6.9 6.6 23 4.8 1.2 3.2 2 0 0 2 2 2 0 TPR repeat LIP PF03583.14 EMG50207.1 - 2.7e-105 351.8 0.0 3.3e-105 351.5 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.20 EMG50207.1 - 0.00036 20.3 0.0 0.032 13.9 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMG50207.1 - 0.022 14.3 0.6 5.8 6.3 0.2 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family NUDIX PF00293.28 EMG50208.1 - 1.5e-13 50.9 0.1 3.2e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EMG50208.1 - 4.3e-06 26.3 0.1 7.4e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 EMG50208.1 - 0.00073 20.2 0.0 0.0033 18.1 0.0 2.1 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zinc_ribbon_2 PF13240.6 EMG50208.1 - 0.32 10.8 3.8 0.11 12.2 0.6 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 EMG50208.1 - 1.8 8.5 4.0 19 5.3 4.0 2.2 1 1 0 1 1 1 0 Nudix N-terminal Sec5 PF15469.6 EMG50209.1 - 1.3e-40 139.3 20.6 1.3e-40 139.3 20.6 3.7 3 0 0 3 3 3 1 Exocyst complex component Sec5 DDE_1 PF03184.19 EMG50210.1 - 1.5e-19 70.3 0.0 3.7e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EMG50210.1 - 7.7e-08 32.3 0.2 1.1e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain GDPD PF03009.17 EMG50211.1 - 1e-20 74.6 0.0 2.7e-20 73.2 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF1987 PF09345.10 EMG50211.1 - 0.039 13.6 0.3 0.29 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) Myb_DNA-bind_6 PF13921.6 EMG50213.1 - 3.5e-19 68.8 5.5 5.8e-13 48.9 0.2 4.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMG50213.1 - 2.5e-18 66.0 15.3 3.8e-10 39.8 0.1 4.2 5 0 0 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EMG50213.1 - 7.3e-05 23.1 3.4 7.3e-05 23.1 3.4 4.2 3 2 1 4 4 4 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EMG50213.1 - 0.041 14.0 0.7 0.041 14.0 0.7 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3926 PF13080.6 EMG50213.1 - 0.061 13.3 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) E1_dh PF00676.20 EMG50213.1 - 0.51 9.2 4.6 0.87 8.5 4.6 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component ACOX PF01756.19 EMG50214.1 - 3.5e-34 117.9 0.0 6.5e-34 117.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EMG50214.1 - 6.5e-23 80.8 0.3 2.3e-22 79.0 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EMG50214.1 - 1.6e-11 44.9 0.0 4e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EMG50214.1 - 2e-06 28.1 0.2 0.00064 20.0 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain RAC_head PF16717.5 EMG50214.1 - 0.025 15.5 0.8 0.076 14.0 0.8 1.8 1 0 0 1 1 1 0 Ribosome-associated complex head domain MFS_1 PF07690.16 EMG50215.1 - 6.9e-20 71.3 27.1 7.4e-20 71.2 23.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Hpre_diP_synt_I PF07456.11 EMG50215.1 - 0.053 13.5 0.2 0.053 13.5 0.2 2.8 4 0 0 4 4 4 0 Heptaprenyl diphosphate synthase component I Metallophos PF00149.28 EMG50216.1 - 9e-40 137.3 1.6 1.7e-39 136.5 1.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EMG50216.1 - 1e-15 57.9 0.1 2.3e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain MoCF_biosynth PF00994.24 EMG50217.1 - 6.5e-27 94.0 0.0 1.1e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF5347 PF17282.2 EMG50217.1 - 0.13 12.6 0.0 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5347) MFS_1 PF07690.16 EMG50218.1 - 1.7e-54 185.1 88.7 1.4e-28 99.9 32.7 3.4 2 2 2 4 4 4 4 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG50218.1 - 9.7e-09 34.6 73.5 0.0021 17.0 8.0 5.3 3 2 1 4 4 4 4 Sugar (and other) transporter MtlR PF05068.12 EMG50218.1 - 0.026 14.5 0.3 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Mannitol repressor Tmemb_9 PF05434.11 EMG50218.1 - 0.13 12.1 0.2 0.86 9.5 0.1 2.1 2 0 0 2 2 2 0 TMEM9 ChlI PF13541.6 EMG50218.1 - 0.14 12.0 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase Syja_N PF02383.18 EMG50219.1 - 2.8e-80 270.0 1.6 2.8e-80 270.0 1.6 2.4 3 1 0 3 3 3 1 SacI homology domain RP-C_C PF11800.8 EMG50219.1 - 4.4 7.3 10.4 11 6.0 10.4 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region ABC2_membrane PF01061.24 EMG50220.1 - 1.3e-06 28.0 2.2 1.8e-06 27.5 2.2 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EMG50221.1 - 9.9e-16 58.5 0.0 1.2e-15 58.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EMG50221.1 - 1.6e-05 24.8 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EMG50221.1 - 0.00055 20.4 0.0 0.00074 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMG50221.1 - 0.00069 20.2 0.0 0.0014 19.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMG50221.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EMG50221.1 - 0.0027 18.2 0.1 0.0043 17.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 EMG50221.1 - 0.0039 16.8 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 EMG50221.1 - 0.0079 16.1 0.1 0.037 13.9 0.1 1.8 1 1 1 2 2 2 1 Deoxynucleoside kinase AAA_29 PF13555.6 EMG50221.1 - 0.0084 15.8 0.5 0.029 14.1 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMG50221.1 - 0.0084 16.4 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMG50221.1 - 0.0094 16.5 0.1 0.013 16.0 0.1 1.3 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EMG50221.1 - 0.011 14.5 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class TsaE PF02367.17 EMG50221.1 - 0.012 15.6 0.2 0.026 14.5 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 EMG50221.1 - 0.013 15.6 0.1 0.024 14.7 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 EMG50221.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EMG50221.1 - 0.028 14.6 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMG50221.1 - 0.031 14.6 0.0 0.045 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase MobB PF03205.14 EMG50221.1 - 0.035 14.0 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 EMG50221.1 - 0.035 13.8 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 EMG50221.1 - 0.049 11.6 0.0 0.049 11.6 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_28 PF13521.6 EMG50221.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EMG50221.1 - 0.13 11.5 0.1 0.22 10.7 0.1 1.5 1 1 0 1 1 1 0 Septin AAA_21 PF13304.6 EMG50221.1 - 0.16 11.7 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 EMG50222.1 - 1.7e-27 95.1 0.1 3.2e-27 94.3 0.0 1.5 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane PF01061.24 EMG50222.1 - 2.2e-11 43.6 2.1 2.2e-11 43.6 2.1 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EMG50222.1 - 0.0034 16.5 2.0 0.0065 15.6 2.0 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein Cyclin PF08613.11 EMG50223.1 - 9.5e-35 120.3 2.9 3.1e-34 118.7 3.0 1.9 1 1 0 1 1 1 1 Cyclin DNA_pol_phi PF04931.13 EMG50223.1 - 0.017 13.3 21.1 0.029 12.5 21.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi Cyclin_N PF00134.23 EMG50223.1 - 0.043 13.6 0.8 0.079 12.7 0.6 1.6 1 1 0 1 1 1 0 Cyclin, N-terminal domain TFIIA PF03153.13 EMG50223.1 - 0.51 10.3 21.1 1.4 8.8 14.4 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Mak16 PF04874.14 EMG50223.1 - 3.1 8.4 15.1 26 5.5 11.7 2.3 2 0 0 2 2 2 0 Mak16 protein C-terminal region FYDLN_acid PF09538.10 EMG50223.1 - 3.1 8.5 19.9 1 10.1 13.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Cwf_Cwc_15 PF04889.12 EMG50223.1 - 9.4 5.9 22.9 2.4 7.8 17.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ABC_trans_N PF14510.6 EMG50224.1 - 1.3e-11 45.0 0.1 2.5e-11 44.0 0.1 1.7 1 1 0 1 1 1 1 ABC-transporter N-terminal ABC_tran PF00005.27 EMG50224.1 - 1.2e-05 25.9 0.0 2.7e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 ABC transporter SHMT PF00464.19 EMG50226.1 - 3.6e-210 697.6 0.0 4.1e-210 697.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EMG50226.1 - 1.5e-07 31.0 0.0 3.5e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMG50226.1 - 0.00051 19.1 0.0 0.00077 18.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMG50226.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EMG50226.1 - 0.024 13.2 0.0 0.049 12.2 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme TCTP PF00838.17 EMG50226.1 - 0.16 12.3 1.5 1.4 9.3 0.1 2.2 1 1 1 2 2 2 0 Translationally controlled tumour protein ORMDL PF04061.14 EMG50227.1 - 2.6e-56 189.2 5.0 3.6e-56 188.7 5.0 1.2 1 0 0 1 1 1 1 ORMDL family RCC1 PF00415.18 EMG50228.1 - 1.5e-19 70.3 2.3 0.00044 20.8 0.3 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMG50228.1 - 2.8e-17 62.0 17.2 5.2e-10 38.9 0.1 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Sugar_tr PF00083.24 EMG50229.1 - 1.6e-111 373.3 22.4 1.9e-111 373.1 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG50229.1 - 9.9e-23 80.6 36.7 1.9e-15 56.7 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 EMG50229.1 - 0.74 10.1 7.1 0.6 10.4 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Sugar_tr PF00083.24 EMG50230.1 - 1.6e-109 366.8 23.4 1.9e-109 366.5 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG50230.1 - 3.8e-18 65.5 36.6 1.4e-12 47.2 10.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily HlyIII PF03006.20 EMG50231.1 - 1.7e-52 178.4 12.3 2.5e-52 177.8 12.3 1.2 1 0 0 1 1 1 1 Haemolysin-III related NAD_binding_2 PF03446.15 EMG50234.1 - 5.8e-36 124.1 0.0 8.7e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMG50234.1 - 2.2e-15 57.0 0.0 3.6e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GFO_IDH_MocA PF01408.22 EMG50234.1 - 0.00093 20.0 0.0 0.0062 17.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_1 PF00175.21 EMG50235.1 - 3.2e-26 92.1 0.0 5e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EMG50235.1 - 1.4e-23 83.1 0.0 2.3e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EMG50235.1 - 1.1e-07 32.1 0.1 0.00025 21.2 0.0 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EMG50235.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Apt1 PF10351.9 EMG50236.1 - 0.071 11.9 1.3 0.065 12.1 1.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 EMG50236.1 - 0.081 12.9 15.1 0.12 12.4 15.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Neurokinin_B PF03823.14 EMG50236.1 - 0.35 10.9 1.3 0.74 9.9 1.3 1.5 1 0 0 1 1 1 0 Neurokinin B SR-25 PF10500.9 EMG50236.1 - 0.68 9.5 13.8 1.1 8.8 13.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EMG50236.1 - 0.79 10.4 10.9 0.19 12.4 7.5 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein AF-4 PF05110.13 EMG50236.1 - 0.84 7.6 13.7 0.83 7.7 13.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 EMG50236.1 - 0.87 8.1 4.3 0.88 8.1 4.3 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 EMG50236.1 - 2.1 6.6 9.8 2.3 6.4 9.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SWI-SNF_Ssr4 PF08549.10 EMG50236.1 - 4.2 5.9 11.4 4.7 5.7 11.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GREB1 PF15782.5 EMG50236.1 - 5.1 4.1 7.0 5.1 4.1 7.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Arrestin_C PF02752.22 EMG50238.1 - 4.4e-16 59.6 0.3 5.8e-12 46.2 0.0 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EMG50238.1 - 1.9e-08 34.5 0.0 1.8e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 EMG50238.1 - 0.0092 15.2 0.4 1.5 7.9 0.1 2.5 2 0 0 2 2 2 2 Rgp1 RNA_pol_Rpc34 PF05158.12 EMG50240.1 - 1.5e-86 290.9 3.2 1.8e-86 290.6 3.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_36 PF13730.6 EMG50240.1 - 0.00034 20.5 1.2 0.1 12.5 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain Rrf2 PF02082.20 EMG50240.1 - 0.014 15.7 1.5 0.024 15.0 0.2 1.9 2 0 0 2 2 2 0 Transcriptional regulator RPA_C PF08784.11 EMG50240.1 - 0.02 15.5 0.1 0.068 13.8 0.0 1.8 2 0 0 2 2 2 0 Replication protein A C terminal HTH_46 PF15977.5 EMG50240.1 - 0.08 13.0 1.3 0.13 12.3 0.4 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding HTH_34 PF13601.6 EMG50240.1 - 0.14 12.4 1.6 0.95 9.7 0.2 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain EIAV_GP90 PF00971.18 EMG50241.1 - 0.17 10.5 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 OTCace PF00185.24 EMG50242.1 - 2.3e-47 161.0 0.3 3.8e-47 160.3 0.3 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EMG50242.1 - 3.9e-43 147.0 0.2 7.7e-43 146.1 0.1 1.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Epimerase PF01370.21 EMG50243.1 - 7.1e-20 71.5 0.1 9.4e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG50243.1 - 2.2e-17 63.0 0.1 3.2e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMG50243.1 - 7.3e-10 38.4 0.0 0.00011 21.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EMG50243.1 - 3.4e-09 36.5 0.2 4.7e-09 36.1 0.2 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMG50243.1 - 4.1e-07 30.1 0.1 6.1e-07 29.5 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMG50243.1 - 0.00024 20.7 0.1 0.00062 19.4 0.1 1.7 2 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EMG50243.1 - 0.0016 17.7 0.4 0.0029 16.8 0.4 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EMG50243.1 - 0.04 13.4 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 EMG50243.1 - 0.084 12.8 0.1 0.76 9.7 0.1 2.1 1 1 0 1 1 1 0 KR domain DUF3589 PF12141.8 EMG50245.1 - 1.5e-161 538.3 2.7 2.3e-161 537.8 2.7 1.3 1 0 0 1 1 1 1 Beta-mannosyltransferases RR_TM4-6 PF06459.12 EMG50245.1 - 0.49 10.2 13.0 0.73 9.6 13.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EMG50245.1 - 7.2 4.8 13.8 10 4.3 13.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Anp1 PF03452.14 EMG50246.1 - 2.2e-63 214.1 0.4 3.1e-63 213.7 0.4 1.1 1 0 0 1 1 1 1 Anp1 MSC PF09402.10 EMG50247.1 - 2.7e-95 319.7 0.0 2.7e-95 319.7 0.0 2.4 2 1 0 2 2 2 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EMG50247.1 - 8.1e-10 38.2 0.0 3.7e-09 36.1 0.0 2.3 1 0 0 1 1 1 1 HeH/LEM domain MttA_Hcf106 PF02416.16 EMG50247.1 - 0.042 13.2 0.2 0.24 10.7 0.0 2.5 2 0 0 2 2 2 0 mttA/Hcf106 family Vps51 PF08700.11 EMG50248.1 - 1.9e-07 31.0 3.2 1.9e-07 31.0 3.2 1.9 2 0 0 2 2 2 1 Vps51/Vps67 NPR1_like_C PF12313.8 EMG50248.1 - 0.012 15.2 0.3 0.02 14.4 0.3 1.4 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal BPL_LplA_LipB PF03099.19 EMG50249.1 - 0.006 16.5 0.1 0.021 14.7 0.1 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF1989 PF09347.10 EMG50250.1 - 6.5e-60 201.6 0.0 8.4e-60 201.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) MFS_1 PF07690.16 EMG50251.1 - 3.3e-18 65.8 25.3 1.5e-17 63.6 22.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3589 PF12141.8 EMG50252.1 - 1e-169 565.3 4.8 1.3e-169 565.0 4.8 1.1 1 0 0 1 1 1 1 Beta-mannosyltransferases PfkB PF00294.24 EMG50253.1 - 1.7e-72 244.3 0.2 2e-72 244.0 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EMG50253.1 - 1.1e-05 24.9 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Spb1_C PF07780.12 EMG50254.1 - 2.7e-83 278.8 25.9 2.7e-83 278.8 25.9 3.6 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 EMG50254.1 - 5.2e-54 183.0 0.0 9.9e-54 182.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EMG50254.1 - 2.9e-41 141.0 14.6 2.9e-41 141.0 14.6 5.7 4 2 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 EMG50254.1 - 0.051 13.4 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain GMC_oxred_C PF05199.13 EMG50257.1 - 3.8e-26 92.3 0.0 5e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMG50258.1 - 5.2e-31 108.1 0.0 6.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EMG50258.1 - 9.8e-05 22.5 0.1 0.00021 21.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMG50258.1 - 0.00014 21.1 0.1 0.00023 20.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMG50258.1 - 0.016 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMG50258.1 - 0.052 12.8 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DUF1374 PF07118.11 EMG50259.1 - 0.0059 17.1 0.4 3.2 8.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1374) IcmF_C PF06744.12 EMG50259.1 - 0.15 11.7 0.1 15 5.1 0.0 2.2 2 0 0 2 2 2 0 Type VI secretion protein IcmF C-terminal Herpes_UL56 PF04534.12 EMG50260.1 - 0.48 9.9 3.0 5.5 6.4 0.0 2.5 2 1 0 2 2 2 0 Herpesvirus UL56 protein DBR1 PF05011.13 EMG50261.1 - 7.5e-23 81.5 0.9 1.8e-22 80.3 0.2 1.9 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EMG50261.1 - 0.00065 20.2 3.2 0.00065 20.2 3.2 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Arginase PF00491.21 EMG50263.1 - 4.3e-87 292.2 0.0 5e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EMG50263.1 - 0.0053 17.0 0.3 0.0086 16.3 0.3 1.3 1 0 0 1 1 1 1 UPF0489 domain F-box-like PF12937.7 EMG50264.1 - 1.1e-05 25.2 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMG50264.1 - 2.8e-05 23.8 0.1 0.00015 21.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain DUF3194 PF11419.8 EMG50264.1 - 0.25 11.7 1.2 5.7 7.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3194) Malic_M PF03949.15 EMG50265.1 - 1.5e-86 289.8 0.0 2.1e-86 289.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EMG50265.1 - 2.3e-62 210.0 0.0 4.8e-62 209.0 0.0 1.5 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Zn_clus PF00172.18 EMG50266.1 - 1.5e-06 28.2 6.1 2.6e-06 27.4 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_1 PF00175.21 EMG50267.1 - 4.1e-26 91.8 0.0 6.5e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EMG50267.1 - 2.4e-24 85.6 0.0 4.2e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EMG50267.1 - 6.1e-08 32.9 0.1 0.00017 21.7 0.0 2.7 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Mito_carr PF00153.27 EMG50268.1 - 3.6e-30 103.7 0.9 4.9e-15 55.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NAD_Gly3P_dh_N PF01210.23 EMG50269.1 - 3.8e-51 173.2 0.0 6.1e-51 172.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EMG50269.1 - 1.2e-39 135.9 0.0 1.9e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EMG50269.1 - 0.00033 21.2 0.3 0.24 12.0 0.0 2.6 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 EMG50269.1 - 0.03 14.7 0.0 0.065 13.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EMG50269.1 - 0.12 12.2 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Rossmann-like domain Carb_kinase PF01256.17 EMG50271.1 - 6.3e-52 176.5 0.0 9.4e-51 172.6 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 EMG50271.1 - 0.00075 19.0 0.1 0.0017 17.8 0.0 1.7 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 EMG50271.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase PfkB PF00294.24 EMG50271.1 - 0.018 14.3 0.2 0.034 13.4 0.1 1.6 1 1 0 1 1 1 0 pfkB family carbohydrate kinase TPR_11 PF13414.6 EMG50273.1 - 0.58 9.9 3.5 1.7 8.4 3.0 2.0 2 0 0 2 2 2 0 TPR repeat Spc24 PF08286.11 EMG50273.1 - 7.3 6.9 11.6 0.16 12.2 1.2 3.2 2 2 1 3 3 3 0 Spc24 subunit of Ndc80 Ribosomal_L23eN PF03939.13 EMG50275.1 - 6.6e-22 77.5 10.2 6.6e-22 77.5 10.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EMG50275.1 - 2.5e-17 63.0 1.8 2.5e-17 63.0 1.8 2.5 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_S11 PF00411.19 EMG50276.1 - 0.0006 20.2 0.0 0.00099 19.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 PLA2_B PF01735.18 EMG50277.1 - 5.2e-191 635.3 5.3 6.9e-191 634.9 5.3 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 EMG50277.1 - 0.11 12.8 1.4 0.2 11.9 1.4 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PLA2_B PF01735.18 EMG50278.1 - 9.7e-177 588.3 4.7 1.2e-176 588.0 4.7 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 EMG50278.1 - 0.066 13.5 1.6 0.16 12.2 1.6 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PLA2_B PF01735.18 EMG50279.1 - 3.7e-176 586.3 2.2 3.7e-176 586.3 2.2 1.5 2 0 0 2 2 2 1 Lysophospholipase catalytic domain PHtD_u1 PF16645.5 EMG50279.1 - 0.056 13.9 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein IBR PF01485.21 EMG50279.1 - 0.096 12.9 1.5 0.26 11.5 1.5 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ADK PF00406.22 EMG50280.1 - 4.1e-60 202.3 0.0 5.9e-60 201.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EMG50280.1 - 3.2e-22 79.4 0.7 7.9e-22 78.1 0.0 1.9 2 1 1 3 3 3 1 AAA domain ADK_lid PF05191.14 EMG50280.1 - 1.5e-17 63.3 0.0 3.7e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EMG50280.1 - 7e-06 26.6 0.0 1.7e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMG50280.1 - 4e-05 23.8 0.0 8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain CART PF06373.11 EMG50280.1 - 0.0047 17.1 0.1 0.016 15.4 0.1 1.8 1 0 0 1 1 1 1 Cocaine and amphetamine regulated transcript protein (CART) Cytidylate_kin PF02224.18 EMG50280.1 - 0.034 13.9 0.0 0.077 12.7 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 EMG50280.1 - 0.081 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain CFIA_Pcf11 PF11526.8 EMG50281.1 - 5.9e-16 58.7 10.6 4.1e-15 56.0 6.8 3.2 2 1 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 Endonuclease_7 PF02945.15 EMG50281.1 - 0.017 15.1 0.5 0.52 10.3 0.0 2.4 2 0 0 2 2 2 0 Recombination endonuclease VII zf_UBZ PF18439.1 EMG50281.1 - 0.033 13.8 0.5 0.15 11.7 0.5 2.1 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger ParD PF09386.10 EMG50281.1 - 0.071 13.5 0.9 0.23 11.9 0.9 1.9 1 0 0 1 1 1 0 Antitoxin ParD DUF2175 PF09943.9 EMG50281.1 - 0.076 13.3 10.3 2.9 8.3 0.4 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) zf-BED PF02892.15 EMG50281.1 - 0.34 11.0 1.7 7.5 6.7 0.2 2.7 2 0 0 2 2 2 0 BED zinc finger Ephrin_rec_like PF07699.13 EMG50281.1 - 0.34 10.7 2.4 0.49 10.2 0.4 2.0 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-HC5HC2H PF13771.6 EMG50281.1 - 0.83 9.9 3.5 37 4.7 0.0 3.0 2 1 0 2 2 2 0 PHD-like zinc-binding domain DEAD PF00270.29 EMG50282.1 - 2.1e-35 122.1 0.4 3.8e-35 121.2 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG50282.1 - 2.1e-33 115.0 3.3 6.9e-30 103.6 0.0 2.9 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EMG50282.1 - 6e-07 29.6 0.1 6e-07 29.6 0.1 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CENP-B_dimeris PF09026.10 EMG50282.1 - 0.021 15.2 1.1 0.058 13.8 0.6 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DnaI_N PF07319.11 EMG50282.1 - 0.025 15.2 1.8 0.82 10.4 0.4 3.0 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus PBP1_TM PF14812.6 EMG50282.1 - 0.64 10.4 6.1 1.8 9.0 6.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TLP-20 PF06088.11 EMG50282.1 - 1.5 8.7 7.5 0.11 12.3 1.4 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CobT PF06213.12 EMG50282.1 - 5.5 6.3 8.3 1.2 8.5 4.5 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT HAD_2 PF13419.6 EMG50283.1 - 1.5e-15 57.7 0.0 2.1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMG50283.1 - 4.5e-10 40.2 0.0 1.4e-09 38.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EMG50283.1 - 0.034 14.2 0.0 13 6.0 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ATR13 PF16829.5 EMG50283.1 - 0.055 13.8 0.0 0.68 10.3 0.0 2.3 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector YL1 PF05764.13 EMG50284.1 - 1.2e-42 146.7 60.6 2.8e-34 119.3 31.2 4.0 2 2 2 4 4 4 2 YL1 nuclear protein YL1_C PF08265.11 EMG50284.1 - 2.4e-10 40.0 0.1 4.1e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Med15_fungi PF05397.12 EMG50284.1 - 3 8.1 10.8 1.6 9.0 0.4 3.3 3 0 0 3 3 3 0 Mediator complex subunit 15 Aha1_N PF09229.11 EMG50285.1 - 1.6e-37 128.8 1.5 1.9e-37 128.5 1.5 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Gemini_coat PF00844.18 EMG50285.1 - 0.091 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family MFS_1 PF07690.16 EMG50286.1 - 1.6e-40 139.1 28.7 1.6e-40 139.1 28.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Fapy_DNA_glyco PF01149.24 EMG50287.1 - 2e-33 115.5 0.1 2.9e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EMG50287.1 - 4.9e-15 55.3 0.0 1.7e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EMG50287.1 - 0.15 10.8 0.0 0.28 9.9 0.0 1.4 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Snf7 PF03357.21 EMG50288.1 - 1.8e-46 157.9 13.4 2.1e-46 157.7 13.4 1.0 1 0 0 1 1 1 1 Snf7 Spc7 PF08317.11 EMG50288.1 - 0.019 13.9 10.4 0.013 14.4 8.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Vps4_C PF09336.10 EMG50288.1 - 0.16 12.0 0.5 0.34 10.9 0.5 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain DUF2120 PF09893.9 EMG50288.1 - 0.17 12.0 4.5 0.15 12.2 2.7 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF1319 PF07028.11 EMG50288.1 - 0.2 11.9 3.7 0.19 12.0 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) FlaC_arch PF05377.11 EMG50288.1 - 0.71 10.3 0.0 0.71 10.3 0.0 4.0 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) LMBR1 PF04791.16 EMG50288.1 - 1.2 8.0 5.4 1.3 7.8 5.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein ABC_tran_CTD PF16326.5 EMG50288.1 - 2.4 8.5 14.4 4.4 7.6 4.2 3.5 3 0 0 3 3 3 0 ABC transporter C-terminal domain Tweety PF04906.13 EMG50288.1 - 2.7 6.5 4.9 2.3 6.8 2.3 1.8 1 1 1 2 2 2 0 Tweety FapA PF03961.13 EMG50288.1 - 2.9 6.4 12.5 1.3 7.6 7.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Atg14 PF10186.9 EMG50288.1 - 3.2 6.8 10.3 6.4 5.8 10.2 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_MT_bd PF06657.13 EMG50288.1 - 4.7 7.7 9.0 17 5.9 1.8 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Methyltransf_23 PF13489.6 EMG50289.1 - 3.6e-18 65.9 0.0 5.7e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG50289.1 - 1.8e-17 63.8 0.0 3.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMG50289.1 - 2e-14 53.7 0.0 3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG50289.1 - 2.2e-12 47.5 0.0 4.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG50289.1 - 1e-10 42.2 0.0 1.9e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMG50289.1 - 6.7e-07 28.9 0.0 9.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EMG50289.1 - 5.9e-06 25.9 0.0 2.4e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EMG50289.1 - 2.2e-05 24.0 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 EMG50289.1 - 3.4e-05 22.9 0.0 5.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 EMG50289.1 - 6.9e-05 22.3 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EMG50289.1 - 0.00097 18.8 0.3 0.0026 17.4 0.3 1.7 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 EMG50289.1 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 EMG50289.1 - 0.0043 16.2 0.1 0.0082 15.3 0.1 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 EMG50289.1 - 0.02 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EMG50289.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Lipoprotein_9 PF03180.14 EMG50290.1 - 0.00069 18.8 0.2 0.001 18.3 0.2 1.2 1 0 0 1 1 1 1 NLPA lipoprotein DUF1374 PF07118.11 EMG50290.1 - 0.0044 17.5 1.3 0.92 10.1 0.0 3.2 2 2 1 3 3 3 2 Protein of unknown function (DUF1374) Lyase_8_C PF02884.17 EMG50290.1 - 0.09 13.3 0.0 0.45 11.0 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain PH PF00169.29 EMG50291.1 - 1.7e-11 44.6 2.6 2.6e-10 40.7 2.1 2.6 2 0 0 2 2 2 1 PH domain Ribosomal_L14 PF00238.19 EMG50292.1 - 2.5e-33 114.8 0.0 2.8e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e LIM PF00412.22 EMG50293.1 - 1.3e-10 41.4 25.8 9.2e-06 25.8 9.5 2.6 2 0 0 2 2 2 2 LIM domain Glyco_hydro81C PF17652.1 EMG50294.1 - 1.7e-149 497.8 0.9 2.3e-149 497.4 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EMG50294.1 - 3.9e-96 322.0 0.5 5.3e-96 321.6 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Imm72 PF15584.6 EMG50294.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 72 Zn_clus PF00172.18 EMG50295.1 - 6.4e-06 26.2 9.9 6.4e-06 26.2 9.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclophil_like PF04126.13 EMG50295.1 - 0.17 11.8 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin-like Zn_clus PF00172.18 EMG50296.1 - 2.7e-05 24.2 6.8 4.9e-05 23.3 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_6 PF13516.6 EMG50298.1 - 7.7e-07 28.7 1.3 1.6 9.0 0.2 5.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.6 EMG50298.1 - 3.4e-06 26.7 10.6 5.5e-05 22.8 0.1 5.5 6 1 0 6 6 6 1 Leucine rich repeat LRR_4 PF12799.7 EMG50298.1 - 0.0034 17.8 33.9 0.24 11.9 0.7 8.9 8 4 0 8 8 8 3 Leucine Rich repeats (2 copies) FNIP PF05725.12 EMG50298.1 - 0.0091 16.1 15.0 3.4 7.9 0.1 6.6 7 1 1 8 8 8 2 FNIP Repeat LRR_1 PF00560.33 EMG50298.1 - 3.4 8.6 13.4 54 4.9 0.4 6.9 6 0 0 6 6 6 0 Leucine Rich Repeat Pkinase PF00069.25 EMG50299.1 - 9.3e-55 185.8 0.0 2.3e-52 178.0 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50299.1 - 9.5e-25 87.3 0.0 5e-23 81.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG50299.1 - 2.3e-05 23.9 0.0 3.4e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMG50299.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMG50299.1 - 0.057 13.3 0.0 0.15 12.0 0.0 1.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family UPF0220 PF05255.11 EMG50300.1 - 3.1e-69 231.8 6.4 3.5e-69 231.6 6.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) WD40 PF00400.32 EMG50301.1 - 7e-31 105.8 13.0 1.4e-05 25.7 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50301.1 - 7.9e-21 74.2 0.1 1.9e-05 24.9 0.1 5.5 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMG50301.1 - 2.3e-09 36.4 2.7 0.045 12.4 0.0 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EMG50301.1 - 4.5e-08 32.8 10.0 0.00015 21.2 0.2 3.6 3 1 1 4 4 4 3 WD40-like domain Utp8 PF10395.9 EMG50301.1 - 2.8e-07 29.5 2.3 0.00018 20.2 0.5 2.8 2 1 0 3 3 3 2 Utp8 family Ge1_WD40 PF16529.5 EMG50301.1 - 4.2e-06 26.0 0.1 2.6 6.9 0.0 4.4 2 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EMG50301.1 - 6.5e-06 26.2 0.1 0.047 13.6 0.0 3.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 EMG50301.1 - 0.0005 18.5 0.6 0.031 12.6 0.1 2.6 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 EMG50301.1 - 0.004 15.7 0.0 0.14 10.6 0.1 2.6 2 1 0 3 3 3 1 Cytochrome D1 heme domain DUF4979 PF16351.5 EMG50301.1 - 0.054 13.7 0.6 0.68 10.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4979) ELYS-bb PF16687.5 EMG50301.1 - 0.077 11.6 0.0 0.23 10.0 0.0 1.6 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin PD40 PF07676.12 EMG50301.1 - 4.4 7.4 5.4 1.9 8.5 0.1 3.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Pkinase PF00069.25 EMG50302.1 - 8.2e-70 235.2 0.1 8.2e-70 235.2 0.1 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50302.1 - 1.9e-46 158.4 0.0 3.7e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG50302.1 - 2.3e-07 30.4 0.0 6.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DUF4502 PF14950.6 EMG50302.1 - 0.14 11.6 7.1 0.2 11.0 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) Androgen_recep PF02166.16 EMG50302.1 - 0.93 8.3 4.6 1.7 7.4 4.6 1.4 1 0 0 1 1 1 0 Androgen receptor Cyclin_C_2 PF16899.5 EMG50303.1 - 0.038 14.4 1.4 0.38 11.2 0.7 2.7 2 1 0 2 2 2 0 Cyclin C-terminal domain BCDHK_Adom3 PF10436.9 EMG50303.1 - 0.044 13.6 2.3 0.39 10.5 0.3 2.4 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase dCache_3 PF14827.6 EMG50303.1 - 0.095 12.3 1.6 6 6.4 0.9 2.4 2 0 0 2 2 2 0 Double sensory domain of two-component sensor kinase Antimicrobial19 PF08225.11 EMG50303.1 - 0.34 10.6 5.5 1.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Pseudin antimicrobial peptide RhoGAP PF00620.27 EMG50304.1 - 0.00014 21.8 5.4 0.00015 21.6 0.2 3.0 3 0 0 3 3 3 1 RhoGAP domain Rot1 PF10681.9 EMG50304.1 - 0.076 12.5 0.2 0.2 11.2 0.2 1.7 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal PSDC PF12588.8 EMG50304.1 - 0.087 12.8 2.4 0.29 11.1 0.0 3.0 3 0 0 3 3 3 0 Phophatidylserine decarboxylase TAFH PF07531.14 EMG50304.1 - 0.17 12.0 5.4 0.21 11.7 0.1 3.3 3 0 0 3 3 3 0 NHR1 homology to TAF CENP-O PF09496.10 EMG50305.1 - 1.7e-26 93.5 0.1 1.7e-26 93.5 0.1 2.0 2 1 0 2 2 2 1 Cenp-O kinetochore centromere component CENP-F_leu_zip PF10473.9 EMG50305.1 - 0.0052 16.8 1.8 0.018 15.1 1.8 1.8 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 EMG50305.1 - 0.032 14.6 0.5 0.098 13.1 0.5 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF2730 PF10805.8 EMG50305.1 - 0.13 12.4 0.7 0.41 10.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Fungal_TACC PF12709.7 EMG50305.1 - 0.13 12.7 3.4 0.18 12.3 1.4 2.3 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins APG6_N PF17675.1 EMG50305.1 - 0.76 10.3 6.5 0.46 11.0 1.9 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 EMG50305.1 - 1.5 8.6 5.2 0.51 10.1 1.8 2.0 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 EMG50305.1 - 3.5 8.1 7.1 2.3 8.7 3.9 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Clathrin PF00637.20 EMG50306.1 - 2.1e-192 630.7 57.3 1.5e-32 112.4 2.0 8.6 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EMG50306.1 - 2e-27 94.9 1.3 2e-27 94.9 1.3 2.4 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.20 EMG50306.1 - 1.8e-21 75.3 4.7 0.00078 19.6 0.1 6.7 6 0 0 6 6 6 4 Clathrin propeller repeat Clathrin-link PF09268.10 EMG50306.1 - 1.6e-08 33.8 0.4 4.6e-08 32.3 0.4 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_2 PF07719.17 EMG50306.1 - 1.9e-06 27.6 4.0 1.2 9.5 0.0 7.7 7 1 1 8 8 8 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EMG50306.1 - 0.00021 20.4 5.9 0.13 11.3 0.2 4.2 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.6 EMG50306.1 - 0.0013 18.6 5.7 28 5.0 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMG50306.1 - 0.0028 17.5 0.1 6.5 6.8 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMG50306.1 - 0.011 16.0 4.7 5.6 7.3 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 EMG50306.1 - 0.063 13.7 2.2 3.5 8.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PQQ_2 PF13360.6 EMG50306.1 - 0.077 12.6 0.0 6.2 6.3 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain TPR_19 PF14559.6 EMG50306.1 - 0.19 12.3 2.2 18 5.9 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMG50306.1 - 0.46 10.8 11.5 9.4 6.7 0.0 7.3 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMG50306.1 - 0.65 10.7 1.9 1.3e+02 3.3 0.3 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Utp13 PF08625.11 EMG50306.1 - 2.4 8.0 5.7 1 9.3 0.2 3.4 5 0 0 5 5 3 0 Utp13 specific WD40 associated domain TPR_1 PF00515.28 EMG50306.1 - 4 7.4 19.5 4.8 7.2 0.0 7.2 10 0 0 10 10 8 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 EMG50307.1 - 1.5e-47 162.1 0.0 1.9e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMG50307.1 - 5.9e-43 146.6 0.1 8.6e-43 146.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG50307.1 - 6.9e-09 35.9 0.0 9.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMG50307.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ODR4-like PF14778.6 EMG50307.1 - 0.075 12.0 0.1 0.097 11.6 0.1 1.2 1 0 0 1 1 1 0 Olfactory receptor 4-like ATP-synt_Eps PF04627.13 EMG50308.1 - 9.1e-18 64.0 0.1 1e-17 63.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain VWA PF00092.28 EMG50308.1 - 0.018 15.3 0.0 0.019 15.2 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain T2SSF PF00482.23 EMG50308.1 - 0.076 13.0 0.1 0.093 12.7 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DNA_pol_phi PF04931.13 EMG50309.1 - 2.7e-175 584.7 42.4 2.7e-175 584.7 42.4 1.8 2 0 0 2 2 2 1 DNA polymerase phi SDA1 PF05285.12 EMG50309.1 - 0.002 17.6 21.3 0.002 17.6 21.3 3.0 3 0 0 3 3 3 2 SDA1 PIG-P PF08510.12 EMG50309.1 - 0.16 11.9 0.0 0.59 10.0 0.0 2.0 1 0 0 1 1 1 0 PIG-P CSTF2_hinge PF14327.6 EMG50309.1 - 1.1 9.8 3.5 32 5.1 0.0 4.0 4 0 0 4 4 4 0 Hinge domain of cleavage stimulation factor subunit 2 BBS2_Mid PF14783.6 EMG50310.1 - 0.021 14.9 0.1 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 EMG50310.1 - 0.25 12.3 4.7 3 8.8 1.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat SHE3 PF17078.5 EMG50311.1 - 1.3e-78 263.8 38.2 1.3e-78 263.8 38.2 2.3 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 SlyX PF04102.12 EMG50311.1 - 0.19 12.4 9.0 12 6.6 2.0 3.8 3 0 0 3 3 3 0 SlyX DUF745 PF05335.13 EMG50311.1 - 0.61 9.8 7.6 1.6 8.4 7.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF4618 PF15397.6 EMG50311.1 - 0.76 9.1 29.2 3 7.2 0.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) HALZ PF02183.18 EMG50311.1 - 1.3 9.3 11.2 9.8 6.5 0.8 4.1 3 1 0 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 EMG50311.1 - 1.4 8.8 15.9 0.18 11.6 1.9 3.3 3 0 0 3 3 3 0 Septum formation initiator DASH_Dam1 PF08653.10 EMG50311.1 - 1.5 8.7 9.5 1.7 8.5 0.7 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 Tup_N PF08581.10 EMG50311.1 - 2.9 8.3 21.2 0.14 12.5 5.8 3.7 3 0 0 3 3 3 0 Tup N-terminal DUF3450 PF11932.8 EMG50311.1 - 4.5 6.5 20.5 0.3 10.3 4.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 EMG50311.1 - 6.6 7.0 19.4 0.41 10.9 4.9 3.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DEAD PF00270.29 EMG50312.1 - 1.1e-24 87.1 0.1 5.7e-24 84.8 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG50312.1 - 1.8e-16 60.4 0.3 1.2e-15 57.8 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG50312.1 - 7.6e-08 32.5 0.5 2.3e-07 31.0 0.3 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EMG50312.1 - 0.016 15.5 0.1 2.3 8.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain DAP3 PF10236.9 EMG50313.1 - 1.7e-70 237.7 2.2 2.5e-70 237.1 2.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Ribosomal_S2 PF00318.20 EMG50313.1 - 0.052 12.8 3.6 0.087 12.0 2.6 1.8 1 1 0 1 1 1 0 Ribosomal protein S2 AAA_14 PF13173.6 EMG50313.1 - 0.068 13.2 3.3 0.074 13.1 0.1 2.7 3 1 0 3 3 3 0 AAA domain ResIII PF04851.15 EMG50313.1 - 0.11 12.5 5.4 0.13 12.3 3.8 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EMG50313.1 - 0.16 12.3 0.0 0.63 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain UPF0113_N PF17833.1 EMG50314.1 - 2.3e-31 108.2 0.1 3.5e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EMG50314.1 - 1e-24 86.6 0.0 1.9e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain PseudoU_synth_1 PF01416.20 EMG50315.1 - 1.4e-17 64.1 0.0 1.4e-13 51.3 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pkinase PF00069.25 EMG50316.1 - 1.5e-25 90.0 0.0 1.5e-25 90.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50316.1 - 1.4e-14 54.1 0.1 2.6e-14 53.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG50316.1 - 4.9e-09 35.5 7.7 8.4e-09 34.7 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EMG50316.1 - 8.6e-05 22.6 3.4 0.0029 17.5 0.0 3.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family SRP-alpha_N PF04086.13 EMG50316.1 - 0.45 10.4 20.3 0.62 9.9 20.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal WD40 PF00400.32 EMG50317.1 - 1.4e-06 28.9 2.8 0.038 14.9 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50317.1 - 0.00078 19.7 0.0 0.16 12.3 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup54 PF13874.6 EMG50318.1 - 0.0065 16.6 4.9 0.015 15.4 2.4 2.5 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 CYLD_phos_site PF16607.5 EMG50318.1 - 0.01 15.7 0.1 0.031 14.1 0.1 1.8 1 1 0 1 1 1 0 Phosphorylation region of CYLD, unstructured Lipoprotein_20 PF13942.6 EMG50318.1 - 0.56 10.1 6.0 0.072 13.0 1.2 1.9 2 0 0 2 2 2 0 YfhG lipoprotein DUF724 PF05266.14 EMG50318.1 - 1.9 8.3 8.2 2.4 7.9 7.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.20 EMG50318.1 - 6 6.9 11.9 17 5.4 10.1 2.7 1 1 1 2 2 2 0 Prefoldin subunit CorA PF01544.18 EMG50318.1 - 9.8 5.4 11.5 1.7 7.9 0.8 2.6 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein RRM_1 PF00076.22 EMG50319.1 - 1.5e-11 43.9 1.4 7e-11 41.8 0.1 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMG50319.1 - 0.00046 20.3 0.0 0.00083 19.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 EMG50319.1 - 0.013 15.5 1.7 0.095 12.8 0.2 2.5 2 1 0 2 2 2 0 Limkain b1 Peptidase_M13 PF01431.21 EMG50319.1 - 0.018 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M13 Sod_Cu PF00080.20 EMG50319.1 - 0.042 14.0 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) CBS PF00571.28 EMG50320.1 - 8e-27 93.5 3.5 7.6e-10 39.1 0.2 4.3 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.11 EMG50320.1 - 0.15 12.2 1.1 1.7 8.8 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain OPT PF03169.15 EMG50321.1 - 1.7e-148 496.0 20.4 2e-148 495.8 20.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein LRR19-TM PF15176.6 EMG50321.1 - 7.2 6.7 5.1 1.3 9.0 0.0 2.3 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain KH_1 PF00013.29 EMG50322.1 - 2.9e-37 126.3 4.8 6.5e-12 45.1 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EMG50322.1 - 4.3e-09 36.1 2.7 0.0065 16.3 0.0 3.7 4 0 0 4 4 4 3 KH domain KH_4 PF13083.6 EMG50322.1 - 1.5e-06 28.0 0.0 0.43 10.5 0.0 3.8 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EMG50322.1 - 0.076 13.1 2.3 8.9 6.5 0.2 3.2 3 0 0 3 3 3 0 NusA-like KH domain BCNT PF07572.12 EMG50323.1 - 1e-23 83.2 1.4 2.5e-23 81.9 1.4 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development Peptidase_M49 PF03571.15 EMG50324.1 - 1.4e-219 730.1 0.3 2.2e-219 729.4 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M49 ABC_membrane PF00664.23 EMG50324.1 - 1e-45 156.5 8.2 1.6e-45 155.9 8.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMG50324.1 - 5.1e-29 101.5 2.5 5.3e-29 101.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EMG50324.1 - 5.1e-07 29.4 0.0 7.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMG50324.1 - 0.00012 22.4 0.6 0.0018 18.5 0.2 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMG50324.1 - 0.0025 18.2 0.1 0.014 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 EMG50324.1 - 0.0041 16.0 0.2 0.0078 15.0 0.2 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class DEAD PF00270.29 EMG50324.1 - 0.011 15.5 0.4 0.097 12.4 0.4 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EMG50324.1 - 0.14 11.9 0.0 0.36 10.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 EMG50324.1 - 9.6 6.2 13.1 4.4 7.3 0.2 3.9 4 0 0 4 4 4 0 Helicase HerA, central domain PLU-1 PF08429.11 EMG50325.1 - 0.0016 17.7 0.0 0.002 17.4 0.0 1.1 1 0 0 1 1 1 1 PLU-1-like protein HTH_7 PF02796.15 EMG50325.1 - 0.13 12.4 0.3 1.2 9.3 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase GMC_oxred_N PF00732.19 EMG50326.1 - 1.1e-24 87.3 0.2 1.4e-24 87.1 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EMG50326.1 - 5.2e-05 23.4 0.2 9.6e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMG50326.1 - 6.5e-05 22.2 0.7 8e-05 21.9 0.7 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMG50326.1 - 0.0095 15.2 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Stirrup PF09061.6 EMG50326.1 - 0.096 12.9 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Stirrup FAD_binding_3 PF01494.19 EMG50326.1 - 0.1 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_C PF05199.13 EMG50327.1 - 1e-25 90.9 0.0 1.4e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase WD40 PF00400.32 EMG50328.1 - 0.0099 16.7 0.0 0.06 14.2 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50328.1 - 0.011 16.0 0.0 0.037 14.3 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain FTCD_C PF04961.12 EMG50328.1 - 0.18 11.6 1.9 0.49 10.1 1.9 1.7 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF445 PF04286.12 EMG50328.1 - 0.98 9.2 30.5 0.43 10.3 10.7 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF445) DUF1664 PF07889.12 EMG50328.1 - 1.4 8.9 13.2 0.3 11.1 2.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Bac_small_YrzI PF09501.10 EMG50328.1 - 1.7 8.9 4.2 1.1 9.4 0.2 3.0 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Tweety PF04906.13 EMG50328.1 - 3.2 6.3 4.7 6.9 5.2 0.3 2.2 2 0 0 2 2 2 0 Tweety YtxH PF12732.7 EMG50328.1 - 3.3 8.3 13.7 1.7e+02 2.8 7.7 5.1 2 2 0 2 2 2 0 YtxH-like protein zf-C3HC4_2 PF13923.6 EMG50329.1 - 3.2e-09 36.5 12.2 3.2e-09 36.5 12.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 EMG50329.1 - 3.6e-08 33.0 0.0 2.2e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 SAP domain zf-C3HC4 PF00097.25 EMG50329.1 - 3.5e-07 30.0 13.9 3.5e-07 30.0 13.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG50329.1 - 5e-07 29.6 18.3 6.1e-06 26.2 6.3 3.6 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EMG50329.1 - 3.3e-06 26.8 18.1 1.2e-05 25.0 12.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMG50329.1 - 3.7e-06 27.0 11.1 3.7e-06 27.0 11.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EMG50329.1 - 1.5e-05 24.7 4.8 1.5e-05 24.7 4.8 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 EMG50329.1 - 5.3e-05 23.5 18.9 8.5e-05 22.8 12.6 2.4 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EMG50329.1 - 0.00011 22.0 17.9 0.0071 16.2 13.3 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EMG50329.1 - 0.00074 19.4 21.3 0.00079 19.3 16.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 EMG50329.1 - 0.0012 19.0 7.7 0.0012 19.0 7.7 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EMG50329.1 - 0.0034 17.6 7.4 0.0034 17.6 7.4 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain Pex14_N PF04695.13 EMG50329.1 - 0.011 16.4 4.4 0.011 16.4 4.4 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region U-box PF04564.15 EMG50329.1 - 0.024 14.8 0.1 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 U-box domain DZR PF12773.7 EMG50329.1 - 0.51 10.4 9.3 4.9 7.3 6.8 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-WRNIP1_ubi PF18279.1 EMG50329.1 - 3.6 8.4 8.2 0.66 10.8 0.9 2.9 3 0 0 3 3 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-piccolo PF05715.13 EMG50329.1 - 6.4 7.0 14.2 7.9 6.7 0.2 3.4 3 0 0 3 3 3 0 Piccolo Zn-finger Form_Nir_trans PF01226.17 EMG50330.1 - 2.8e-60 203.6 28.3 3.4e-60 203.3 28.3 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter LapA_dom PF06305.11 EMG50330.1 - 0.089 12.6 1.4 1.3 8.9 0.0 3.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Phos_pyr_kin PF08543.12 EMG50331.1 - 8e-10 38.5 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EMG50331.1 - 9.5e-06 25.1 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SUR7 PF06687.12 EMG50332.1 - 1.6e-34 119.4 14.3 1.9e-34 119.2 14.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EMG50332.1 - 4.4e-05 23.5 9.2 4.4e-05 23.5 9.2 1.5 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 CD225 PF04505.12 EMG50332.1 - 0.38 10.9 0.1 0.38 10.9 0.1 3.2 3 0 0 3 3 3 0 Interferon-induced transmembrane protein Wzy_C PF04932.15 EMG50332.1 - 0.98 9.0 8.8 15 5.2 6.1 2.8 2 1 0 2 2 2 0 O-Antigen ligase Lipase_3 PF01764.25 EMG50333.1 - 6.4e-07 29.3 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EMG50333.1 - 0.0086 16.7 0.0 0.015 16.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 EMG50333.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 EMG50333.1 - 0.046 13.4 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Fmp27 PF10344.9 EMG50334.1 - 4.5e-163 544.5 36.0 4.5e-163 544.5 36.0 1.9 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 EMG50334.1 - 2.1e-62 211.5 20.9 1.7e-40 139.3 8.2 2.3 1 1 1 2 2 2 2 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EMG50334.1 - 5.3e-54 182.6 0.1 1.6e-53 181.0 0.0 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EMG50334.1 - 1.8e-52 177.4 0.3 1e-51 174.9 0.3 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EMG50334.1 - 1e-29 103.3 1.8 2e-29 102.3 0.2 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Ribosomal_L32e PF01655.18 EMG50335.1 - 1.1e-46 157.6 2.3 1.4e-46 157.3 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 tRNA-synt_1e PF01406.19 EMG50335.1 - 0.028 13.8 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF3437 PF11919.8 EMG50335.1 - 0.036 14.0 0.1 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) SPACA7 PF15307.6 EMG50335.1 - 0.064 13.5 0.0 6.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 Pkinase PF00069.25 EMG50336.1 - 2.5e-42 145.1 0.0 3.7e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50336.1 - 1.1e-21 77.3 0.0 1.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG50336.1 - 3.8e-06 26.4 0.0 7.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMG50336.1 - 0.0052 16.2 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ChAPs PF09295.10 EMG50336.1 - 0.041 12.9 0.5 0.078 12.0 0.5 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) YrbL-PhoP_reg PF10707.9 EMG50336.1 - 0.07 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Rubella_Capsid PF05750.11 EMG50336.1 - 0.71 9.4 9.7 1.6 8.3 9.7 1.6 1 0 0 1 1 1 0 Rubella capsid protein MFS_1 PF07690.16 EMG50337.1 - 4.5e-06 25.8 18.2 3.9e-05 22.7 15.4 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EMG50337.1 - 0.00055 18.3 0.6 0.16 10.2 0.0 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Apt1 PF10351.9 EMG50338.1 - 1.6e-102 343.9 15.4 2e-102 343.5 15.4 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain DNApol_Exo PF18136.1 EMG50339.1 - 8.7e-97 323.6 0.5 2.5e-96 322.2 0.5 1.8 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EMG50339.1 - 1.2e-55 189.2 0.0 2.5e-55 188.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EMG50339.1 - 0.071 12.8 0.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 3'-5' exonuclease CDC45 PF02724.14 EMG50340.1 - 0.0017 16.8 17.1 0.002 16.5 17.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 EMG50340.1 - 0.0031 16.0 22.0 0.0038 15.7 22.0 1.1 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 EMG50340.1 - 0.0062 16.0 24.3 0.0074 15.8 24.3 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 EMG50340.1 - 0.0081 15.5 18.9 0.0096 15.3 18.9 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 EMG50340.1 - 0.12 10.5 29.7 0.16 10.2 29.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 EMG50340.1 - 0.18 10.7 3.5 0.27 10.2 3.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 EMG50340.1 - 0.25 10.5 3.5 0.059 12.6 0.4 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Vfa1 PF08432.10 EMG50340.1 - 0.35 11.2 12.4 0.53 10.6 12.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CNDH2_C PF16858.5 EMG50340.1 - 0.37 10.6 10.9 0.47 10.3 10.9 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DNA_pol_phi PF04931.13 EMG50340.1 - 0.81 7.7 38.7 1.1 7.2 38.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC27 PF09507.10 EMG50340.1 - 1.2 8.4 17.9 1.6 8.1 17.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CobT PF06213.12 EMG50340.1 - 1.4 8.2 28.6 1.9 7.8 28.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.13 EMG50340.1 - 2.1 7.2 22.5 2.9 6.8 22.5 1.1 1 0 0 1 1 1 0 Paf1 SAPS PF04499.15 EMG50340.1 - 2.1 7.0 9.9 3.1 6.5 9.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2151 PF10221.9 EMG50340.1 - 2.3 6.7 5.5 2.8 6.4 5.5 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4746 PF15928.5 EMG50340.1 - 2.4 7.5 18.7 3.4 7.0 18.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_Rpc4 PF05132.14 EMG50340.1 - 2.7 8.4 5.8 4.2 7.8 5.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPN2_C PF18004.1 EMG50340.1 - 2.7 7.9 11.0 4.7 7.1 11.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Tim54 PF11711.8 EMG50340.1 - 3.4 6.3 9.9 4.8 5.9 9.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 EMG50340.1 - 3.6 6.3 6.1 4.7 5.9 6.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PPP4R2 PF09184.11 EMG50340.1 - 7.9 6.0 26.9 14 5.2 26.9 1.4 1 0 0 1 1 1 0 PPP4R2 Merozoite_SPAM PF07133.11 EMG50340.1 - 9.5 6.2 45.2 16 5.4 45.2 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF4746 PF15928.5 EMG50341.1 - 0.0021 17.6 1.0 0.0021 17.6 1.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4746) BUD22 PF09073.10 EMG50341.1 - 0.079 12.3 29.6 0.03 13.7 5.0 2.5 2 0 0 2 2 2 0 BUD22 PWWP PF00855.17 EMG50342.1 - 1.2e-14 54.5 0.0 1.2e-14 54.5 0.0 3.7 3 1 1 4 4 4 1 PWWP domain Med26 PF08711.11 EMG50342.1 - 1.2e-05 25.3 0.0 4.5e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain MEIOC PF15189.6 EMG50342.1 - 0.0013 18.4 0.3 0.0031 17.2 0.3 1.6 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC DUF3439 PF11921.8 EMG50342.1 - 0.068 13.1 2.4 0.17 11.9 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) HTH_40 PF14493.6 EMG50342.1 - 0.58 10.7 4.6 0.42 11.1 0.2 2.9 2 1 1 3 3 3 0 Helix-turn-helix domain DGF-1_C PF11040.8 EMG50342.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.3 3 1 1 4 4 4 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus eIF-5a PF01287.20 EMG50343.1 - 4.4e-30 103.6 0.6 6.3e-30 103.1 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EMG50343.1 - 0.019 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain zf-RING_2 PF13639.6 EMG50344.1 - 3.5e-12 46.4 6.9 5.7e-12 45.8 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMG50344.1 - 5.7e-09 35.7 7.3 9.4e-09 35.0 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMG50344.1 - 2.1e-08 33.8 2.8 3.9e-08 32.9 2.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EMG50344.1 - 8.5e-07 28.8 4.8 1.4e-06 28.2 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EMG50344.1 - 1.5e-06 28.3 9.1 6e-06 26.4 9.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EMG50344.1 - 1.6e-06 27.9 6.0 2.8e-06 27.1 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EMG50344.1 - 1.6e-06 28.1 1.8 3.2e-06 27.1 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EMG50344.1 - 1.7e-06 27.9 1.0 4e-06 26.7 0.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EMG50344.1 - 0.00063 19.3 5.2 0.0012 18.5 5.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EMG50344.1 - 0.0017 18.2 4.7 0.0027 17.6 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMG50344.1 - 0.0087 15.9 4.7 0.024 14.5 4.7 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 PHD PF00628.29 EMG50344.1 - 0.039 13.9 6.4 0.07 13.0 6.4 1.5 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 EMG50344.1 - 0.053 13.6 3.0 0.14 12.2 3.0 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger DUF5453 PF17534.2 EMG50344.1 - 0.067 13.1 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5453) TMEM51 PF15345.6 EMG50344.1 - 0.15 11.9 0.0 0.15 11.9 0.0 3.2 4 0 0 4 4 3 0 Transmembrane protein 51 zf-RING_4 PF14570.6 EMG50344.1 - 0.16 11.8 6.2 0.32 10.8 6.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 EMG50344.1 - 0.44 10.5 6.4 0.074 13.0 1.8 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 EMG50344.1 - 0.48 10.6 3.8 1.6 8.9 3.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EMG50344.1 - 1.4 9.2 7.4 2.7 8.2 7.4 1.5 1 0 0 1 1 1 0 RING-variant domain Orf78 PF06024.12 EMG50344.1 - 1.9 8.9 0.0 1.9 8.9 0.0 4.1 4 0 0 4 4 4 0 Orf78 (ac78) zf-C3HC4_4 PF15227.6 EMG50344.1 - 2.1 8.6 6.0 4.3 7.6 6.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FoP_duplication PF13865.6 EMG50344.1 - 2.7 8.6 17.9 1.5 9.4 6.5 2.8 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 EMG50345.1 - 5.9e-09 35.6 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rox3 PF08633.10 EMG50346.1 - 5.6e-17 62.7 0.4 7.6e-16 59.0 0.4 2.1 1 1 0 1 1 1 1 Rox3 mediator complex subunit Gly_transf_sug PF04488.15 EMG50347.1 - 1.6e-14 54.3 0.0 7e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif KIAA1430 PF13879.6 EMG50347.1 - 0.043 14.6 0.1 0.088 13.6 0.1 1.5 1 0 0 1 1 1 0 KIAA1430 homologue Abhydro_lipase PF04083.16 EMG50348.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF5086 PF16985.5 EMG50348.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) zf-H2C2_2 PF13465.6 EMG50349.1 - 0.00055 20.2 17.4 0.0033 17.8 7.3 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EMG50349.1 - 0.022 15.2 17.9 0.15 12.6 2.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG50349.1 - 0.084 13.8 17.5 1.8 9.6 7.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger M-factor PF03855.13 EMG50350.1 - 0.27 11.4 2.3 6.4 7.0 0.1 2.8 2 0 0 2 2 2 0 M-factor MFS_1 PF07690.16 EMG50351.1 - 5.6e-39 134.1 36.0 3.4e-36 124.9 39.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG50351.1 - 1.5e-13 50.4 7.0 1.5e-13 50.4 7.0 3.0 3 1 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.13 EMG50351.1 - 2.7e-09 36.0 26.8 4.6e-09 35.2 26.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EMG50351.1 - 0.0013 17.2 7.4 0.0013 17.2 7.4 2.9 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family UPF0126 PF03458.13 EMG50351.1 - 0.98 9.3 6.7 2.7 8.0 0.4 3.2 2 0 0 2 2 2 0 UPF0126 domain Gpr1_Fun34_YaaH PF01184.19 EMG50352.1 - 1.4e-78 263.2 25.8 1.6e-78 263.0 25.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Oxidored_FMN PF00724.20 EMG50353.1 - 4.7e-89 299.0 0.0 5.6e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RE_CfrBI PF09516.10 EMG50353.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 CfrBI restriction endonuclease Gpr1_Fun34_YaaH PF01184.19 EMG50354.1 - 3.8e-75 252.0 25.7 4.4e-75 251.8 25.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 EMG50355.1 - 6.5e-71 238.2 22.4 7.6e-71 238.0 22.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Oxidored_FMN PF00724.20 EMG50356.1 - 1.4e-96 323.7 0.0 1.6e-96 323.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DnaJ PF00226.31 EMG50358.1 - 7.1e-28 96.5 1.3 1.2e-27 95.8 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EMG50358.1 - 3.7e-20 72.5 0.0 5.6e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EMG50358.1 - 3.1e-14 53.1 19.7 5.8e-14 52.2 19.7 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EMG50358.1 - 1.6e-05 24.8 8.1 0.017 15.1 0.7 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EMG50358.1 - 0.0056 16.7 3.6 0.4 10.7 0.2 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GET2 PF08690.10 EMG50358.1 - 0.15 11.7 0.1 0.21 11.3 0.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 PIG-X PF08320.12 EMG50359.1 - 1.5e-29 103.5 0.0 2.4e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 Mog1 PF04603.12 EMG50360.1 - 8.7e-33 113.6 0.2 1.1e-32 113.3 0.2 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Flocculin_t3 PF13928.6 EMG50361.1 - 2.3e-10 40.8 28.4 2.3e-10 40.8 28.4 4.9 4 1 0 4 4 4 1 Flocculin type 3 repeat AA_permease_2 PF13520.6 EMG50362.1 - 2.6e-58 197.9 41.1 3.5e-58 197.4 41.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG50362.1 - 6.7e-15 54.6 38.0 8.7e-15 54.3 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease DEAD PF00270.29 EMG50363.1 - 9.5e-48 162.3 0.0 1e-46 158.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG50363.1 - 1.7e-22 79.8 0.0 1.7e-22 79.8 0.0 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EMG50363.1 - 1.2e-15 57.4 7.3 1.2e-15 57.4 7.3 3.2 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Ribosomal_S19e PF01090.19 EMG50364.1 - 4.5e-51 172.2 0.0 5.4e-51 171.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Channel_Tsx PF03502.13 EMG50364.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Nucleoside-specific channel-forming protein, Tsx Peptidase_C14 PF00656.22 EMG50365.1 - 5.7e-63 213.2 0.1 8e-63 212.7 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Cas_Csm6 PF09659.10 EMG50365.1 - 0.024 13.5 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) Ras PF00071.22 EMG50366.1 - 3.4e-46 156.8 0.8 5.9e-46 156.0 0.8 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EMG50366.1 - 6e-15 55.5 0.0 1.1e-13 51.5 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EMG50366.1 - 1.7e-05 24.9 0.1 2.3e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EMG50366.1 - 0.002 17.6 0.1 0.0072 15.8 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EMG50366.1 - 0.0031 17.0 0.0 0.0052 16.2 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EMG50366.1 - 0.0049 16.4 0.1 2.1 7.8 0.0 2.3 2 1 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EMG50366.1 - 0.0051 16.4 0.3 0.31 10.5 0.3 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 EMG50366.1 - 0.02 14.9 0.1 0.042 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMG50366.1 - 0.022 14.7 0.3 2.3 8.1 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase TniB PF05621.11 EMG50366.1 - 0.084 12.3 0.0 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Zn_clus PF00172.18 EMG50367.1 - 3.1e-09 36.8 9.3 5.9e-09 35.9 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ring_hydroxyl_B PF00866.18 EMG50367.1 - 3.1 7.9 5.7 7.3 6.7 0.5 2.4 2 0 0 2 2 2 0 Ring hydroxylating beta subunit FAD-oxidase_C PF02913.19 EMG50368.1 - 7.1e-61 206.0 0.0 9.3e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMG50368.1 - 4.7e-35 120.3 0.0 9.6e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Peptidase_M14 PF00246.24 EMG50369.1 - 1.1e-63 215.7 0.9 1.3e-63 215.6 0.0 1.5 2 0 0 2 2 2 1 Zinc carboxypeptidase Endotoxin_C PF03944.14 EMG50369.1 - 0.053 13.9 0.5 0.11 12.9 0.5 1.5 1 0 0 1 1 1 0 delta endotoxin Trm5_N PF18093.1 EMG50369.1 - 0.081 12.8 0.3 0.18 11.7 0.3 1.6 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain F-box PF00646.33 EMG50370.1 - 0.00031 20.6 0.2 0.00069 19.4 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMG50370.1 - 0.0043 16.9 1.6 0.0053 16.6 0.1 1.9 2 0 0 2 2 2 1 F-box-like FtsK_SpoIIIE_N PF12538.8 EMG50370.1 - 0.07 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 DNA transporter Endosulfine PF04667.17 EMG50371.1 - 1.1e-31 108.8 1.4 1.7e-31 108.1 1.4 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region S-antigen PF05756.11 EMG50371.1 - 0.052 13.9 0.4 0.17 12.3 0.1 1.8 2 0 0 2 2 2 0 S-antigen protein Autophagy_act_C PF03987.15 EMG50372.1 - 2.5e-13 50.4 0.7 2.5e-13 50.4 0.7 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Thi4 PF01946.17 EMG50374.1 - 1.1e-105 352.1 0.0 1.3e-105 351.8 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EMG50374.1 - 9.1e-08 32.1 1.4 2.2e-06 27.5 0.7 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMG50374.1 - 4.2e-07 29.5 0.1 6.5e-07 28.9 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMG50374.1 - 2.3e-06 26.9 0.8 5.6e-05 22.4 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EMG50374.1 - 5.8e-06 25.6 0.2 1.5e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMG50374.1 - 1.5e-05 25.1 0.1 3.7e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMG50374.1 - 0.00014 21.3 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EMG50374.1 - 0.00076 18.7 0.2 0.0014 17.8 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EMG50374.1 - 0.0012 17.6 0.3 0.0023 16.7 0.3 1.5 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 EMG50374.1 - 0.0013 18.7 0.2 0.0041 17.1 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMG50374.1 - 0.002 17.4 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMG50374.1 - 0.0027 16.6 0.2 0.0044 15.9 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase CheC PF04509.12 EMG50374.1 - 0.39 10.7 1.3 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 CheC-like family UPF0020 PF01170.18 EMG50375.1 - 3.5e-11 43.2 0.0 1.3e-09 38.0 0.0 2.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EMG50375.1 - 0.00053 19.8 0.0 0.015 15.0 0.0 2.4 2 1 0 2 2 2 1 DNA methylase N6_Mtase PF02384.16 EMG50375.1 - 0.00073 18.9 0.0 0.003 16.9 0.0 2.1 2 1 0 2 2 2 1 N-6 DNA Methylase Cons_hypoth95 PF03602.15 EMG50375.1 - 0.058 13.0 0.0 0.32 10.6 0.0 2.2 1 1 0 1 1 1 0 Conserved hypothetical protein 95 MFS_1 PF07690.16 EMG50376.1 - 6.7e-05 22.0 8.4 0.00035 19.6 7.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily CD225 PF04505.12 EMG50376.1 - 0.19 11.9 4.3 0.35 11.0 0.1 2.9 3 0 0 3 3 3 0 Interferon-induced transmembrane protein MgtC PF02308.16 EMG50376.1 - 0.33 11.3 7.4 1.1 9.7 7.5 1.9 1 1 0 1 1 1 0 MgtC family Bax1-I PF01027.20 EMG50376.1 - 2.8 7.7 13.8 4 7.2 13.1 1.5 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Flocculin_t3 PF13928.6 EMG50377.1 - 3.8e-18 65.7 59.7 1.4e-10 41.5 33.2 9.6 6 1 1 7 7 7 2 Flocculin type 3 repeat MFS_1 PF07690.16 EMG50378.1 - 1.9e-06 27.1 7.9 8.9e-05 21.6 9.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily HlyIII PF03006.20 EMG50378.1 - 0.014 15.2 2.8 0.018 14.8 2.8 1.2 1 0 0 1 1 1 0 Haemolysin-III related EAV_GS PF01309.18 EMG50378.1 - 0.29 10.8 2.8 2.2 7.9 0.8 2.7 2 1 0 2 2 2 0 Equine arteritis virus small envelope glycoprotein Bax1-I PF01027.20 EMG50378.1 - 0.69 9.7 12.6 0.51 10.1 10.7 1.6 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF3533 PF12051.8 EMG50379.1 - 4.8e-125 417.4 22.0 6e-125 417.1 22.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.12 EMG50379.1 - 0.0004 20.2 0.1 0.0004 20.2 0.1 3.1 3 0 0 3 3 3 1 CDR ABC transporter DUF1566 PF07603.11 EMG50379.1 - 0.024 15.0 0.2 0.047 14.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) SAGA-Tad1 PF12767.7 EMG50380.1 - 6.8e-52 176.5 5.5 6.8e-52 176.5 5.5 1.7 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 EMG50380.1 - 2.9e-05 24.0 0.6 8.1e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Microtub_bd PF16796.5 EMG50381.1 - 3.6e-07 30.2 4.1 0.0004 20.3 1.1 4.0 3 2 1 4 4 4 2 Microtubule binding Fib_alpha PF08702.10 EMG50381.1 - 9.2 6.5 33.9 3.2 7.9 0.8 3.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family MFS_1 PF07690.16 EMG50383.1 - 3.3e-26 92.1 68.6 5.3e-26 91.4 62.8 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.15 EMG50384.1 - 8.2e-146 486.2 31.2 9.6e-146 486.0 31.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.15 EMG50385.1 - 1.6e-146 488.6 28.6 1.8e-146 488.4 28.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_1 PF00561.20 EMG50386.1 - 1.5e-14 54.3 0.0 1.4e-12 47.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMG50386.1 - 2.4e-08 33.5 0.0 1.1e-05 24.9 0.0 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMG50386.1 - 1.2e-07 32.5 0.0 2.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.8 EMG50386.1 - 0.0018 17.5 0.2 0.066 12.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Esterase PF00756.20 EMG50386.1 - 0.015 15.0 0.0 0.074 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 EMG50386.1 - 0.047 13.5 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase SopA PF13981.6 EMG50387.1 - 0.0079 16.6 0.4 0.021 15.2 0.4 1.7 1 1 0 1 1 1 1 SopA-like central domain S1-like PF14444.6 EMG50387.1 - 0.0095 15.9 0.2 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 S1-like PNP_UDP_1 PF01048.20 EMG50388.1 - 8.1e-47 159.4 0.0 9.7e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.32 EMG50389.1 - 1.9e-11 44.3 13.8 0.0014 19.4 0.2 5.2 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50389.1 - 0.00012 22.3 0.7 0.051 13.9 0.1 2.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PG_binding_1 PF01471.18 EMG50390.1 - 0.068 13.4 0.6 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 Putative peptidoglycan binding domain SPX PF03105.19 EMG50391.1 - 0.33 10.8 19.5 0.11 12.4 16.4 1.7 1 1 0 1 1 1 0 SPX domain Methyltransf_23 PF13489.6 EMG50394.1 - 1.9e-14 53.8 0.0 2.9e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG50394.1 - 7.7e-10 39.3 0.0 5.2e-09 36.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMG50394.1 - 9.3e-10 38.5 0.5 3.9e-09 36.5 0.5 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG50394.1 - 1e-08 35.8 0.4 5e-08 33.6 0.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG50394.1 - 1.4e-07 32.1 0.0 2.1e-06 28.3 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain NodS PF05401.11 EMG50394.1 - 0.007 16.0 0.0 3.2 7.3 0.0 2.7 2 1 1 3 3 3 2 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 EMG50394.1 - 0.0083 15.5 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Zn_clus PF00172.18 EMG50396.1 - 3.1e-09 36.8 15.0 5.1e-09 36.1 15.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 EMG50396.1 - 0.026 14.6 7.2 0.091 12.8 7.2 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ammonium_transp PF00909.21 EMG50397.1 - 7.9e-106 354.1 26.7 9.4e-106 353.9 26.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TPP_enzyme_N PF02776.18 EMG50398.1 - 1.3e-55 187.7 0.2 3.6e-55 186.2 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMG50398.1 - 1e-49 168.2 1.7 3.3e-48 163.4 0.4 3.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMG50398.1 - 2.1e-42 144.1 0.3 5.3e-42 142.8 0.3 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EMG50398.1 - 0.0055 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CO_dh PF02552.16 EMG50398.1 - 0.067 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit adh_short PF00106.25 EMG50399.1 - 8.9e-22 77.5 0.0 4.2e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMG50399.1 - 3e-12 46.6 0.0 2.8e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG50399.1 - 1.1e-09 38.4 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMG50399.1 - 0.00047 19.7 0.0 0.00078 19.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMG50399.1 - 0.0031 16.7 0.1 0.0041 16.3 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MFS_1 PF07690.16 EMG50400.1 - 1.7e-35 122.6 38.4 1.7e-35 122.6 38.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMG50400.1 - 0.0011 17.5 4.6 0.0011 17.5 4.6 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Kri1_C PF12936.7 EMG50402.1 - 5.7e-32 109.7 5.9 5.7e-32 109.7 5.9 4.5 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 EMG50402.1 - 3.8e-17 62.7 12.0 3.8e-17 62.7 12.0 5.9 2 1 3 6 6 6 1 KRI1-like family HTH_30 PF13556.6 EMG50402.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain zf-C3HC4_2 PF13923.6 EMG50403.1 - 8.5e-10 38.3 8.8 8.5e-10 38.3 8.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMG50403.1 - 1e-09 38.1 10.2 1e-09 38.1 10.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMG50403.1 - 1.5e-08 34.8 9.5 1.5e-08 34.8 9.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EMG50403.1 - 2.2e-08 34.0 6.0 6.6e-08 32.4 6.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EMG50403.1 - 3.2e-08 33.3 7.6 3.2e-08 33.3 7.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMG50403.1 - 4.3e-07 30.1 5.5 4.3e-07 30.1 5.5 2.4 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EMG50403.1 - 1.8e-06 28.0 11.6 1.8e-06 28.0 11.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EMG50403.1 - 0.00011 22.1 8.8 0.00011 22.1 8.8 2.4 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EMG50403.1 - 0.00015 21.5 7.8 0.00015 21.5 7.8 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 EMG50403.1 - 0.0094 16.1 0.0 0.06 13.5 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-RING_6 PF14835.6 EMG50403.1 - 0.011 15.5 3.1 0.011 15.5 3.1 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein NlpE PF04170.12 EMG50403.1 - 0.012 16.5 0.1 0.032 15.2 0.1 1.7 1 0 0 1 1 1 0 NlpE N-terminal domain zf-RING_4 PF14570.6 EMG50403.1 - 0.02 14.7 4.7 0.02 14.7 4.7 2.2 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EMG50403.1 - 0.03 14.4 6.8 0.03 14.4 6.8 2.1 2 1 0 2 2 2 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EMG50403.1 - 0.71 10.0 9.5 0.081 13.0 4.4 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger WAPL PF07814.13 EMG50404.1 - 0.00026 19.9 0.2 0.03 13.1 0.0 2.5 1 1 1 2 2 2 2 Wings apart-like protein regulation of heterochromatin DUF155 PF02582.14 EMG50405.1 - 1.2e-40 139.5 0.2 2.1e-40 138.7 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Headcase PF16002.5 EMG50405.1 - 0.13 11.7 0.0 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 Headcase protein SIS PF01380.22 EMG50406.1 - 2.5e-69 231.2 0.1 2.1e-35 121.4 0.1 2.2 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EMG50406.1 - 3e-16 59.8 0.0 5.9e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EMG50406.1 - 2.5e-10 40.3 0.0 5.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EMG50406.1 - 4.2e-05 22.6 0.0 7.8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 EMG50406.1 - 0.12 12.4 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 SIS domain GATase_2 PF00310.21 EMG50406.1 - 0.19 10.4 0.0 0.41 9.3 0.0 1.5 1 1 1 2 2 2 0 Glutamine amidotransferases class-II RRM_1 PF00076.22 EMG50407.1 - 0.018 14.8 0.1 0.057 13.3 0.0 1.9 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M18 PF02127.15 EMG50408.1 - 3.8e-140 467.5 0.0 4.4e-140 467.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) RSB_motif PF16294.5 EMG50408.1 - 0.17 12.2 0.3 0.32 11.3 0.3 1.3 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif DS PF01916.17 EMG50409.1 - 3.4e-129 430.2 0.0 3.9e-129 430.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase NDUFA12 PF05071.16 EMG50410.1 - 6.4e-27 94.2 3.6 6.4e-27 94.2 3.6 1.5 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Mak10 PF04112.13 EMG50411.1 - 1.7e-42 144.8 0.2 3.2e-42 143.9 0.2 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Sec7_N PF12783.7 EMG50411.1 - 0.047 13.6 1.7 0.2 11.5 0.5 2.5 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RAMPs PF03787.15 EMG50411.1 - 0.055 13.5 0.0 0.25 11.3 0.0 2.2 2 1 0 2 2 2 0 RAMP superfamily G-alpha PF00503.20 EMG50412.1 - 1.2e-107 360.1 5.0 1.2e-107 360.1 5.0 1.6 1 1 1 2 2 2 1 G-protein alpha subunit Arf PF00025.21 EMG50412.1 - 3.6e-15 55.8 0.1 4.7e-10 39.2 0.0 2.8 2 0 0 2 2 2 2 ADP-ribosylation factor family TFIIA PF03153.13 EMG50412.1 - 0.014 15.4 12.9 0.019 15.0 12.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_29 PF13555.6 EMG50412.1 - 0.08 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 EMG50412.1 - 0.12 11.7 9.5 0.19 11.0 0.1 2.9 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Ndc1_Nup PF09531.10 EMG50412.1 - 0.3 9.7 8.0 0.37 9.4 8.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 EMG50412.1 - 1.5 8.0 6.5 1.8 7.7 6.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Roc PF08477.13 EMG50412.1 - 2.6 8.3 7.6 1.7 8.9 0.1 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Spt20 PF12090.8 EMG50412.1 - 4.1 7.0 24.6 8.2 6.0 24.6 1.5 1 0 0 1 1 1 0 Spt20 family Macoilin PF09726.9 EMG50412.1 - 6.2 5.3 15.5 8.4 4.8 15.5 1.2 1 0 0 1 1 1 0 Macoilin family Androgen_recep PF02166.16 EMG50412.1 - 7.7 5.2 11.8 11 4.8 11.8 1.1 1 0 0 1 1 1 0 Androgen receptor Pkinase PF00069.25 EMG50413.1 - 4.8e-72 242.5 0.0 6.7e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50413.1 - 2.1e-34 119.0 0.0 3.1e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG50413.1 - 3.2e-06 26.7 0.0 2.4e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EMG50413.1 - 0.0032 16.5 0.9 0.015 14.3 0.9 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EMG50413.1 - 0.075 12.9 1.3 0.085 12.8 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EMG50413.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EMG50413.1 - 0.41 10.2 2.6 0.35 10.4 0.2 1.9 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 EMG50413.1 - 2.4 6.8 6.4 0.13 11.0 0.2 1.8 2 0 0 2 2 2 0 Fungal protein kinase RA PF00788.23 EMG50414.1 - 3.7e-12 46.7 0.2 3.6e-11 43.5 0.0 2.7 3 1 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 EMG50414.1 - 5.2e-06 26.5 0.0 3.1e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EMG50414.1 - 1.9e-05 25.0 0.2 0.0012 19.2 0.0 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) TFIIA PF03153.13 EMG50414.1 - 0.0018 18.4 32.0 0.0029 17.7 32.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EMG50414.1 - 0.076 11.3 21.7 0.1 10.8 21.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ALMT PF11744.8 EMG50414.1 - 7.5 5.3 7.8 31 3.2 7.7 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter Ribosomal_L11_N PF03946.14 EMG50415.1 - 8.2e-22 76.8 0.5 2.2e-21 75.5 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EMG50415.1 - 3e-16 59.7 0.8 5.3e-16 58.9 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain ACBP PF00887.19 EMG50416.1 - 4.5e-21 74.9 0.2 1.5e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 Acyl CoA binding protein TFIIA PF03153.13 EMG50416.1 - 0.0001 22.5 8.5 0.00015 22.0 8.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit IATP PF04568.12 EMG50416.1 - 0.0037 17.6 3.5 0.012 16.0 3.5 1.9 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP NYAP_C PF15452.6 EMG50416.1 - 0.025 14.5 3.0 0.042 13.7 3.0 1.3 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Androgen_recep PF02166.16 EMG50416.1 - 0.027 13.3 8.9 0.038 12.8 8.9 1.2 1 0 0 1 1 1 0 Androgen receptor DUF572 PF04502.13 EMG50416.1 - 0.12 12.0 7.2 0.013 15.2 2.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) Pex14_N PF04695.13 EMG50416.1 - 0.22 12.2 7.6 0.38 11.4 7.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydin_ADK PF17213.3 EMG50416.1 - 0.3 11.3 2.8 0.54 10.5 2.8 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MMR1 PF08505.10 EMG50416.1 - 0.32 11.3 11.5 0.078 13.3 8.4 1.5 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein EIIBC-GUT_N PF03612.14 EMG50416.1 - 0.54 10.0 3.3 0.56 9.9 2.2 1.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Activator_LAG-3 PF11498.8 EMG50416.1 - 1.5 7.7 21.1 2.3 7.1 21.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ANAPC_CDC26 PF10471.9 EMG50416.1 - 1.7 9.5 19.2 0.63 10.9 13.8 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 CSRNP_N PF16019.5 EMG50416.1 - 3.5 7.5 9.6 1.5 8.6 6.4 1.9 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Neur_chan_memb PF02932.16 EMG50416.1 - 6.1 6.8 7.6 2.7 8.0 3.7 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3340 PF11818.8 EMG50416.1 - 9.6 6.3 12.2 3.8 7.6 4.3 2.5 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) WD40 PF00400.32 EMG50417.1 - 5.1e-10 39.8 23.1 0.41 11.6 0.4 8.2 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50417.1 - 5e-08 33.1 7.7 0.4 11.0 0.1 6.2 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EMG50417.1 - 0.0045 16.6 0.2 25 4.3 0.0 3.7 2 2 1 5 5 5 2 PQQ-like domain Nucleoporin_N PF08801.11 EMG50417.1 - 0.014 14.2 3.3 0.09 11.5 0.1 3.0 2 1 1 4 4 4 0 Nup133 N terminal like DUF4894 PF16235.5 EMG50417.1 - 0.063 13.6 4.7 0.1 12.9 2.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4894) PQQ_3 PF13570.6 EMG50417.1 - 0.076 13.5 0.1 4.6 7.9 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain Glyco_hydro_76 PF03663.14 EMG50418.1 - 7.1e-45 154.1 4.7 8.6e-45 153.8 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMG50418.1 - 1.1e-05 24.7 6.6 0.047 12.8 0.3 3.2 1 1 2 3 3 3 3 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EMG50418.1 - 1.3e-05 23.9 0.1 0.029 12.9 0.0 2.3 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 GlcNAc_2-epim PF07221.11 EMG50418.1 - 4.5e-05 22.8 0.2 0.00095 18.5 0.1 2.5 1 1 1 2 2 2 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) C5-epim_C PF06662.13 EMG50418.1 - 0.0019 17.7 0.2 0.0052 16.3 0.0 1.8 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Sterol_MT_C PF08498.10 EMG50419.1 - 2e-27 95.3 0.4 3.2e-27 94.6 0.4 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EMG50419.1 - 8.3e-18 64.8 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG50419.1 - 1.2e-16 61.2 0.0 2.6e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMG50419.1 - 9.9e-16 57.9 0.0 1.9e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMG50419.1 - 7.9e-12 45.0 1.2 1.1e-11 44.5 1.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EMG50419.1 - 2.6e-11 43.6 0.0 3.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG50419.1 - 5.8e-11 43.0 0.0 1.2e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMG50419.1 - 3.5e-07 29.8 0.0 6.2e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 EMG50419.1 - 4.1e-05 23.2 0.0 6.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EMG50419.1 - 0.00032 20.2 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 EMG50419.1 - 0.00092 18.4 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 EMG50419.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EMG50419.1 - 0.0015 18.5 0.3 0.0033 17.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EMG50419.1 - 0.0076 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 EMG50419.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cnd3 PF12719.7 EMG50420.1 - 6.4e-81 271.8 9.1 6.4e-81 271.8 9.1 3.8 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EMG50420.1 - 1.2e-12 48.1 1.0 6.3e-06 26.5 0.3 4.5 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 EMG50420.1 - 6.1e-09 35.4 0.3 0.018 15.3 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 EMG50420.1 - 0.00064 20.2 0.0 14 6.3 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 EMG50420.1 - 0.015 15.3 11.1 0.022 14.8 0.1 5.0 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF16 PF01519.16 EMG50420.1 - 0.017 15.6 1.5 0.017 15.6 1.5 5.8 5 1 1 6 6 6 0 Protein of unknown function DUF16 CRISPR_Cas9_WED PF18061.1 EMG50420.1 - 0.48 10.5 9.6 0.53 10.4 1.0 4.0 3 1 0 3 3 3 0 CRISPR-Cas9 WED domain bZIP_1 PF00170.21 EMG50421.1 - 2.6e-10 40.3 6.8 2.6e-10 40.3 6.8 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EMG50421.1 - 0.00029 20.9 11.7 0.0012 18.9 11.7 2.1 1 1 0 1 1 1 1 Basic region leucine zipper KASH_CCD PF14662.6 EMG50421.1 - 0.0032 17.3 1.3 0.0063 16.4 1.3 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH dsrm PF00035.26 EMG50421.1 - 0.061 14.0 1.0 0.13 13.0 0.3 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif CCD48 PF15799.5 EMG50421.1 - 0.079 11.3 2.5 0.11 10.8 2.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 ERM PF00769.19 EMG50421.1 - 0.1 12.4 7.7 0.45 10.3 7.7 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family SHE3 PF17078.5 EMG50421.1 - 0.24 11.1 6.8 0.042 13.6 1.5 2.0 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 NPV_P10 PF05531.12 EMG50421.1 - 0.49 10.9 3.5 2.3 8.7 0.5 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein bZIP_Maf PF03131.17 EMG50421.1 - 1.1 9.9 11.5 0.21 12.1 7.1 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Apc15p PF05841.11 EMG50421.1 - 5.1 7.9 9.0 0.23 12.3 0.3 2.8 3 0 0 3 3 3 0 Apc15p protein DivIC PF04977.15 EMG50421.1 - 7 6.5 6.1 9 6.2 3.0 2.3 2 0 0 2 2 2 0 Septum formation initiator FmdA_AmdA PF03069.15 EMG50422.1 - 2.7e-171 569.5 0.0 3.1e-171 569.3 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family TauD PF02668.16 EMG50423.1 - 1.1e-51 176.2 0.0 1.4e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sec23_trunk PF04811.15 EMG50424.1 - 3.9e-18 65.9 0.2 2e-13 50.5 0.0 2.2 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EMG50424.1 - 5.4e-18 64.7 0.0 1.5e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EMG50424.1 - 9.6e-09 35.9 0.0 2.7e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EMG50424.1 - 0.0002 21.3 1.1 0.00068 19.6 1.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DUF1749 PF08538.10 EMG50425.1 - 5.3e-95 317.9 0.0 5.9e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 EMG50425.1 - 7.2e-06 25.4 0.0 9.9e-05 21.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EMG50425.1 - 0.0052 16.7 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 EMG50425.1 - 0.0067 17.0 0.0 0.0098 16.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EMG50425.1 - 0.0098 15.5 0.1 0.097 12.2 0.0 2.0 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase DUF900 PF05990.12 EMG50425.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 EMG50425.1 - 0.014 15.0 0.0 0.3 10.7 0.0 2.2 1 1 0 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 EMG50425.1 - 0.04 13.2 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 EMG50425.1 - 0.058 12.5 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Peptidase_S9 PF00326.21 EMG50425.1 - 0.1 12.1 0.0 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 EMG50425.1 - 0.14 11.7 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family ACOX PF01756.19 EMG50426.1 - 6e-41 140.0 0.0 1.3e-40 138.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EMG50426.1 - 6.4e-24 84.0 0.1 1.3e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EMG50426.1 - 7.4e-14 52.4 0.0 1.3e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EMG50426.1 - 1.7e-07 31.6 0.1 1.5e-05 25.2 0.1 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Tom6 PF17112.5 EMG50427.1 - 1.5e-23 82.0 1.2 1.8e-23 81.8 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal LRR_6 PF13516.6 EMG50428.1 - 5.9e-08 32.1 11.4 0.0036 17.2 0.1 7.9 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.7 EMG50428.1 - 4.9e-07 30.0 27.2 0.031 14.7 0.5 6.9 5 2 0 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG50428.1 - 8.2e-05 22.3 19.0 0.06 13.1 0.9 5.6 4 3 0 4 4 4 3 Leucine rich repeat AAA PF00004.29 EMG50428.1 - 0.16 12.4 1.2 0.38 11.2 1.2 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) LRR_3 PF07725.12 EMG50428.1 - 0.46 10.4 3.0 16 5.6 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_1 PF00560.33 EMG50428.1 - 0.49 11.1 11.1 42 5.2 0.1 6.4 8 0 0 8 8 8 0 Leucine Rich Repeat AAA_23 PF13476.6 EMG50429.1 - 3.3e-13 50.6 165.8 2.7e-12 47.6 70.8 8.4 1 1 2 3 3 2 1 AAA domain SMC_N PF02463.19 EMG50429.1 - 2.3e-06 27.2 0.1 2.3e-06 27.2 0.1 4.5 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMG50429.1 - 2.7e-06 27.4 0.1 0.0029 17.5 0.2 5.3 5 3 1 6 6 6 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EMG50429.1 - 7e-06 26.2 0.0 2.7e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EMG50429.1 - 1.7e-05 24.7 30.7 1.7e-05 24.7 30.7 5.4 1 1 4 5 5 2 2 AAA ATPase domain AAA_16 PF13191.6 EMG50429.1 - 0.0055 17.1 0.7 0.23 11.8 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain Rad50_zn_hook PF04423.14 EMG50429.1 - 0.019 14.8 1.1 0.019 14.8 1.1 6.2 7 0 0 7 7 7 0 Rad50 zinc hook motif AAA_29 PF13555.6 EMG50429.1 - 0.023 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Type_III_YscX PF09474.10 EMG50429.1 - 0.067 13.5 2.7 7.2 6.9 0.6 3.7 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) AAA_22 PF13401.6 EMG50429.1 - 0.21 11.8 7.9 0.23 11.7 0.1 3.9 4 0 0 4 4 4 0 AAA domain Acylphosphatase PF00708.18 EMG50429.1 - 3.5 8.1 6.4 13 6.3 0.1 4.7 3 0 0 3 3 3 0 Acylphosphatase RRM_1 PF00076.22 EMG50430.1 - 1.3e-77 255.5 9.8 1.3e-17 63.3 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMG50430.1 - 1.1e-12 47.6 0.1 0.025 14.2 0.0 4.9 4 1 1 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMG50430.1 - 0.0002 21.3 2.8 1 9.4 0.0 5.2 6 0 0 6 6 6 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EMG50430.1 - 0.00021 21.1 0.5 1.6 8.6 0.0 4.9 6 0 0 6 6 6 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EMG50430.1 - 0.033 14.3 0.1 62 3.8 0.0 4.3 4 0 0 4 4 4 0 Limkain b1 RRM_7 PF16367.5 EMG50430.1 - 0.035 14.2 0.2 4.8 7.4 0.0 3.6 3 0 0 3 3 3 0 RNA recognition motif Rhomboid PF01694.22 EMG50431.1 - 6e-26 91.3 16.8 1.2e-25 90.2 16.8 1.5 1 0 0 1 1 1 1 Rhomboid family AAA_21 PF13304.6 EMG50432.1 - 0.002 18.0 1.5 0.0028 17.5 1.5 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ACOX PF01756.19 EMG50433.1 - 4.7e-36 124.0 0.1 1.4e-35 122.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EMG50433.1 - 2.6e-19 69.2 0.0 4.3e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EMG50433.1 - 9.2e-11 42.4 0.3 1.9e-10 41.4 0.3 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EMG50433.1 - 0.0019 18.4 0.2 0.028 14.6 0.2 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Far-17a_AIG1 PF04750.14 EMG50434.1 - 2.5e-08 33.5 11.7 2.9e-07 30.0 11.7 2.0 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein FYVE PF01363.21 EMG50435.1 - 9.3e-13 48.1 6.6 2.2e-12 46.9 6.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger DEAD PF00270.29 EMG50438.1 - 1.3e-35 122.8 0.3 2e-35 122.1 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG50438.1 - 1.4e-27 96.2 0.0 3.1e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG50438.1 - 1.9e-06 28.0 0.2 4.4e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMG50438.1 - 0.0056 16.4 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMG50438.1 - 0.025 14.9 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pal1 PF08316.11 EMG50439.1 - 1.2e-41 142.6 2.5 1.2e-41 142.6 2.5 2.5 3 0 0 3 3 3 1 Pal1 cell morphology protein Sod_Fe_C PF02777.18 EMG50439.1 - 6.6e-14 51.9 0.1 1.5e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Alg6_Alg8 PF03155.15 EMG50440.1 - 8.7e-168 559.2 37.1 1e-167 559.0 37.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TPP_enzyme_N PF02776.18 EMG50441.1 - 5.7e-30 104.2 0.0 9e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMG50441.1 - 4.3e-20 71.9 0.0 1.4e-19 70.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EMG50441.1 - 1.5e-16 60.6 0.0 3.5e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EMG50441.1 - 0.094 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Fungal_trans PF04082.18 EMG50442.1 - 7.6e-33 113.7 5.8 1.4e-32 112.8 5.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG50442.1 - 1.1e-08 35.1 9.9 2.2e-08 34.1 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 EMG50442.1 - 0.53 10.6 9.1 0.16 12.3 5.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Aa_trans PF01490.18 EMG50443.1 - 9.1e-77 258.5 36.3 1.2e-76 258.1 36.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 EMG50443.1 - 0.099 11.4 39.0 0.024 13.5 35.2 1.6 1 1 1 2 2 2 0 Amino acid permease PI3K_1B_p101 PF10486.9 EMG50444.1 - 0.075 10.8 4.4 0.091 10.5 4.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BUD22 PF09073.10 EMG50444.1 - 0.73 9.1 5.8 0.96 8.7 5.8 1.1 1 0 0 1 1 1 0 BUD22 DUF21 PF01595.20 EMG50445.1 - 1.1e-32 113.1 0.0 2.1e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EMG50445.1 - 0.00041 20.7 0.0 0.88 10.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF1738 PF08401.11 EMG50445.1 - 8.7 6.5 6.6 2.3 8.3 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1738) Pkinase PF00069.25 EMG50446.1 - 1.2e-43 149.3 0.0 2e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50446.1 - 3.6e-19 69.1 0.1 9.1e-19 67.7 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase CCDC106 PF15794.5 EMG50446.1 - 0.00039 20.2 8.3 0.00096 18.9 8.3 1.7 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 Kinase-like PF14531.6 EMG50446.1 - 0.039 13.3 0.0 0.086 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EMG50446.1 - 0.06 13.0 0.3 0.92 9.1 0.3 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SPX PF03105.19 EMG50446.1 - 0.33 10.8 22.3 0.63 9.9 22.3 1.4 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 EMG50446.1 - 0.95 7.9 25.3 1.4 7.4 25.3 1.2 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 EMG50446.1 - 6.5 5.8 29.1 9 5.4 29.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Solute_trans_a PF03619.16 EMG50447.1 - 2e-64 217.7 4.3 2.7e-64 217.3 4.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha mIF3 PF14877.6 EMG50448.1 - 6.1e-34 117.2 8.9 9.8e-34 116.5 8.9 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor FAM167 PF11652.8 EMG50448.1 - 0.44 11.1 2.9 1.3 9.5 1.1 2.4 2 0 0 2 2 2 0 FAM167 KH_4 PF13083.6 EMG50449.1 - 0.099 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 KH domain VitD-bind_III PF09164.10 EMG50449.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Ribosomal_S2 PF00318.20 EMG50450.1 - 4e-24 85.0 0.9 1.7e-13 50.3 0.0 2.4 2 1 1 3 3 3 2 Ribosomal protein S2 40S_SA_C PF16122.5 EMG50450.1 - 2.7e-05 25.4 10.8 6.3e-05 24.2 10.8 1.7 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus MFS_1 PF07690.16 EMG50451.1 - 7e-17 61.4 24.3 7e-17 61.4 24.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_pol3_delta PF06144.13 EMG50451.1 - 0.044 13.6 0.4 0.044 13.6 0.4 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit PAT1 PF09770.9 EMG50451.1 - 0.27 9.5 0.1 0.39 8.9 0.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SMI1_KNR4 PF09346.10 EMG50452.1 - 5.4e-45 153.0 0.2 5.6e-44 149.7 0.0 2.6 2 1 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) CBM_20 PF00686.19 EMG50452.1 - 0.052 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Starch binding domain SUKH_5 PF14567.6 EMG50452.1 - 0.068 12.9 0.1 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall Pyr_redox_2 PF07992.14 EMG50453.1 - 1e-33 116.8 1.2 1.3e-33 116.5 1.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMG50453.1 - 3.4e-06 27.5 0.0 0.00026 21.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMG50453.1 - 3.1e-05 23.4 3.1 3.1e-05 23.4 3.1 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMG50453.1 - 0.00037 19.7 0.3 0.0057 15.8 0.1 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMG50453.1 - 0.0065 16.5 0.6 3.6 7.6 0.0 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding Eno-Rase_NADH_b PF12242.8 EMG50453.1 - 0.085 12.6 0.2 7.2 6.5 0.1 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lycopene_cycl PF05834.12 EMG50453.1 - 0.11 11.5 0.2 9.9 5.1 0.1 3.0 2 2 1 4 4 4 0 Lycopene cyclase protein DAO PF01266.24 EMG50453.1 - 1.3 8.5 3.4 4.3 6.8 0.7 2.9 4 0 0 4 4 4 0 FAD dependent oxidoreductase GIDA PF01134.22 EMG50453.1 - 2.9 6.9 7.0 0.9 8.5 1.1 2.8 3 1 1 4 4 4 0 Glucose inhibited division protein A Cyclin_N PF00134.23 EMG50454.1 - 2.4e-14 53.1 0.6 5.8e-14 51.9 0.6 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EMG50454.1 - 0.024 15.0 1.6 0.057 13.8 1.6 2.0 1 1 0 1 1 1 0 Cyclin C-terminal domain VAD1-2 PF15310.6 EMG50454.1 - 0.11 12.4 7.2 0.15 11.9 7.2 1.1 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Zip PF02535.22 EMG50454.1 - 0.17 11.1 0.6 0.23 10.6 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EVI2A PF05399.11 EMG50454.1 - 1 8.9 10.3 1.5 8.4 10.3 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DFP PF04127.15 EMG50455.1 - 4e-18 65.9 0.0 2.4e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Phage_sheath_1 PF04984.14 EMG50455.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain LPD13 PF18825.1 EMG50455.1 - 0.056 13.2 2.1 6.2 6.6 0.4 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 13 Bac_surface_Ag PF01103.23 EMG50456.1 - 3.5e-35 122.1 9.4 5e-35 121.5 9.4 1.2 1 0 0 1 1 1 1 Surface antigen RNase_Zc3h12a PF11977.8 EMG50456.1 - 0.0035 17.1 0.9 0.0054 16.5 0.1 1.7 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain POTRA PF07244.15 EMG50456.1 - 0.053 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Surface antigen variable number repeat WD40 PF00400.32 EMG50457.1 - 2.3e-06 28.2 7.7 0.57 11.1 0.0 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50457.1 - 5e-06 26.7 1.4 0.054 13.8 0.2 4.4 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMG50457.1 - 0.015 14.2 0.0 0.26 10.2 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DIE2_ALG10 PF04922.12 EMG50458.1 - 3e-102 342.9 25.6 3.7e-101 339.3 25.6 2.2 1 1 0 1 1 1 1 DIE2/ALG10 family Rick_17kDa_Anti PF05433.15 EMG50459.1 - 1.4e-08 34.4 7.7 1.4e-08 34.4 7.7 3.2 2 1 0 2 2 2 1 Glycine zipper 2TM domain Kinesin PF00225.23 EMG50460.1 - 3.8e-119 397.5 0.3 5.9e-119 396.9 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMG50460.1 - 2.1e-26 92.7 0.0 6.3e-26 91.1 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding TRAM_LAG1_CLN8 PF03798.16 EMG50461.1 - 1.2e-34 119.8 19.5 1.3e-34 119.6 19.5 1.0 1 0 0 1 1 1 1 TLC domain DUF4834 PF16118.5 EMG50461.1 - 0.034 15.1 0.0 0.25 12.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TRAP_alpha PF03896.16 EMG50461.1 - 0.075 12.2 1.6 0.17 11.1 1.6 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.8 EMG50461.1 - 0.53 9.2 3.9 0.7 8.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TLP-20 PF06088.11 EMG50461.1 - 0.57 10.0 5.9 0.86 9.5 5.9 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NOA36 PF06524.12 EMG50461.1 - 1.5 8.1 9.1 2.5 7.3 9.1 1.3 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 EMG50462.1 - 1.1e-24 87.2 0.4 2.3e-24 86.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50462.1 - 7.7e-12 45.0 0.0 1.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG50462.1 - 1.8e-08 33.6 3.7 2.4e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Rrn6 PF10214.9 EMG50462.1 - 0.17 10.3 11.6 0.24 9.8 11.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAM60A PF15396.6 EMG50462.1 - 0.79 9.7 4.0 13 5.7 2.6 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Methyltransf_12 PF08242.12 EMG50464.1 - 3.5e-14 53.4 0.0 6.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMG50464.1 - 1.4e-13 51.0 0.0 2.1e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG50464.1 - 1.5e-12 48.0 0.0 2.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG50464.1 - 2.7e-12 47.2 0.0 4.5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMG50464.1 - 8.6e-12 45.1 0.1 1.3e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMG50464.1 - 1.6e-06 27.7 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMG50464.1 - 9.4e-06 25.1 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EMG50464.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.16 EMG50464.1 - 0.0036 16.5 0.1 0.0051 16.0 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme PrmA PF06325.13 EMG50464.1 - 0.0068 15.8 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EMG50464.1 - 0.0078 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase NNMT_PNMT_TEMT PF01234.17 EMG50464.1 - 0.033 13.4 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CheR PF01739.18 EMG50464.1 - 0.037 13.5 0.1 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PCMT PF01135.19 EMG50464.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UQ_con PF00179.26 EMG50465.1 - 4.6e-22 78.2 0.3 8.7e-22 77.3 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Sel1 PF08238.12 EMG50466.1 - 2.2e-47 158.4 25.8 4.9e-08 33.4 0.1 8.4 7 1 1 8 8 8 7 Sel1 repeat ATP-grasp_6 PF18419.1 EMG50466.1 - 0.16 11.6 0.0 0.47 10.1 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp-like domain TauD PF02668.16 EMG50467.1 - 2.8e-24 86.3 0.3 7.9e-24 84.9 0.0 1.8 2 1 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family EF-hand_4 PF12763.7 EMG50468.1 - 2.7e-07 30.5 0.2 2.7e-07 30.5 0.2 2.7 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Arg_decarbox_C PF17944.1 EMG50468.1 - 0.14 12.7 0.8 8.6 7.0 0.1 2.9 1 1 1 2 2 2 0 Arginine decarboxylase C-terminal helical extension TFIIA PF03153.13 EMG50468.1 - 6.8 6.6 38.8 4.3 7.2 29.0 2.1 1 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PIN_6 PF17146.4 EMG50469.1 - 6.1e-32 110.0 0.0 1.4e-31 108.8 0.0 1.7 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EMG50469.1 - 3.3e-26 91.2 1.1 6.2e-26 90.4 1.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 EMG50469.1 - 0.0071 16.4 2.6 0.019 15.1 1.7 2.1 2 0 0 2 2 2 1 Zinc ribbon domain eIF-3c_N PF05470.12 EMG50469.1 - 0.072 11.4 3.8 0.11 10.8 3.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Trypan_PARP PF05887.11 EMG50469.1 - 5 7.1 24.3 8.7 6.3 24.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GST_N PF02798.20 EMG50470.1 - 8.9e-11 42.0 0.0 1.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMG50470.1 - 2.7e-08 34.1 0.0 5.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMG50470.1 - 3.7e-08 33.5 0.0 6.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMG50470.1 - 1.2e-06 28.7 0.0 3.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMG50470.1 - 1.7e-06 28.1 0.0 3.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMG50470.1 - 2.8e-05 24.0 0.0 6.2e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMG50470.1 - 0.00065 20.2 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Interferon PF00143.19 EMG50470.1 - 0.15 12.3 0.0 1.1 9.4 0.0 2.2 2 1 1 3 3 3 0 Interferon alpha/beta domain HDA2-3 PF11496.8 EMG50471.1 - 1.8e-62 211.1 7.3 1.8e-62 211.1 7.3 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 FliJ PF02050.16 EMG50471.1 - 0.017 15.3 4.2 0.017 15.3 4.2 3.3 2 1 1 3 3 3 0 Flagellar FliJ protein CALCOCO1 PF07888.11 EMG50471.1 - 0.024 13.5 24.9 0.041 12.7 24.9 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like LMBR1 PF04791.16 EMG50471.1 - 3.7 6.3 18.2 4.6 6.0 12.8 2.4 2 0 0 2 2 2 0 LMBR1-like membrane protein Pyridoxal_deC PF00282.19 EMG50472.1 - 6.4e-17 61.3 0.0 9e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 EMG50472.1 - 1.1e-07 31.5 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EMG50472.1 - 6.7e-06 25.3 0.0 1.9e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EMG50472.1 - 0.027 13.0 0.0 0.047 12.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme VIT1 PF01988.19 EMG50473.1 - 6.7e-62 209.2 1.9 6.7e-62 209.2 1.9 1.8 2 0 0 2 2 2 1 VIT family PQ-loop PF04193.14 EMG50474.1 - 2.9e-33 113.4 21.6 3.8e-17 61.8 1.2 3.3 4 0 0 4 4 4 2 PQ loop repeat MtN3_slv PF03083.16 EMG50474.1 - 0.087 12.9 0.1 0.087 12.9 0.1 2.6 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange TauD PF02668.16 EMG50476.1 - 2.7e-17 63.5 0.5 2e-16 60.6 0.2 2.0 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Proteasome PF00227.26 EMG50477.1 - 3e-59 199.7 0.1 3.7e-59 199.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMG50477.1 - 2.2e-13 49.6 1.0 3.8e-13 48.9 0.3 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Filament PF00038.21 EMG50477.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF5132 PF17195.4 EMG50478.1 - 0.0064 16.6 0.5 0.012 15.7 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF5132) Peptidase_C48 PF02902.19 EMG50479.1 - 5.4e-09 36.2 4.7 5.4e-09 36.2 4.7 1.9 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain U3_snoRNA_assoc PF08297.11 EMG50479.1 - 0.0013 19.4 0.5 0.17 12.6 1.5 2.3 2 0 0 2 2 2 1 U3 snoRNA associated Peptidase_M24 PF00557.24 EMG50480.1 - 3.9e-50 170.4 0.0 5.1e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EMG50480.1 - 6.4e-35 119.6 0.0 1.1e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GLTP PF08718.11 EMG50481.1 - 0.12 12.6 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Hyr1 PF15789.5 EMG50483.1 - 2.8e-06 26.8 8.9 2.8e-06 26.8 8.9 3.7 3 1 0 3 3 3 1 Hyphally regulated cell wall GPI-anchored protein 1 Mitofilin PF09731.9 EMG50483.1 - 0.05 12.4 10.6 0.051 12.4 10.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SLC12 PF03522.15 EMG50483.1 - 0.27 10.2 2.8 0.29 10.1 2.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 EMG50483.1 - 0.36 10.6 10.0 0.49 10.2 10.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1631 PF07793.11 EMG50483.1 - 1.1 7.6 3.5 1.2 7.5 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Nop14 PF04147.12 EMG50483.1 - 1.4 7.0 13.5 1.5 6.9 13.5 1.0 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 EMG50483.1 - 1.7 7.8 8.4 1.9 7.6 8.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 EMG50483.1 - 1.9 6.7 9.0 2.1 6.6 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.6 EMG50483.1 - 2 9.0 14.3 2.2 8.8 14.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.17 EMG50483.1 - 2.2 7.0 13.4 2.5 6.8 13.4 1.1 1 0 0 1 1 1 0 Presenilin PNISR PF15996.5 EMG50483.1 - 2.3 8.4 14.0 3 8.1 14.0 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF913 PF06025.12 EMG50483.1 - 3.1 6.7 10.6 3.7 6.4 10.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PRCC PF10253.9 EMG50483.1 - 3.2 8.5 21.9 3.7 8.3 21.9 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SpoIIIAH PF12685.7 EMG50483.1 - 4.5 7.1 14.7 5.8 6.7 14.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SDA1 PF05285.12 EMG50483.1 - 4.5 6.6 17.3 4.9 6.5 17.3 1.1 1 0 0 1 1 1 0 SDA1 SPX PF03105.19 EMG50483.1 - 4.9 7.0 21.0 5.2 6.9 21.0 1.1 1 0 0 1 1 1 0 SPX domain NPR3 PF03666.13 EMG50483.1 - 4.9 5.8 13.0 5.8 5.6 13.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Plasmodium_Vir PF05795.11 EMG50483.1 - 7 6.0 13.0 8 5.8 13.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ASD2 PF08687.11 EMG50483.1 - 7.2 6.1 8.4 10 5.6 8.4 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 GEMIN8 PF15348.6 EMG50483.1 - 7.4 6.8 12.6 9.5 6.4 12.6 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 AIF_C PF14721.6 EMG50483.1 - 9.2 6.6 10.6 4.5 7.6 2.9 2.1 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Striatin PF08232.12 EMG50483.1 - 9.4 6.8 11.2 13 6.3 11.2 1.2 1 0 0 1 1 1 0 Striatin family FAM76 PF16046.5 EMG50483.1 - 9.8 5.4 7.0 12 5.2 7.0 1.1 1 0 0 1 1 1 0 FAM76 protein Arginase PF00491.21 EMG50484.1 - 7.9e-74 248.7 0.2 1e-73 248.3 0.2 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EMG50484.1 - 0.0036 17.5 0.2 0.0067 16.7 0.2 1.5 1 1 0 1 1 1 1 UPF0489 domain KRE9 PF05390.11 EMG50485.1 - 6.8e-42 142.4 16.2 1.4e-41 141.3 16.2 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 EMG50485.1 - 1.9e-16 60.6 3.9 2.8e-16 60.0 1.0 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Orf78 PF06024.12 EMG50486.1 - 0.007 16.6 0.0 0.0085 16.4 0.0 1.2 1 0 0 1 1 1 1 Orf78 (ac78) DUF5305 PF17231.2 EMG50486.1 - 0.016 14.6 0.1 0.018 14.5 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5305) OCRL_clath_bd PF16726.5 EMG50486.1 - 0.05 13.8 0.4 0.069 13.3 0.4 1.2 1 0 0 1 1 1 0 Inositol polyphosphate 5-phosphatase clathrin binding domain DUF5345 PF17280.2 EMG50486.1 - 0.095 12.7 0.0 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5345) SKN1 PF03935.15 EMG50487.1 - 5.8e-248 823.3 5.2 7.3e-248 822.9 5.2 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF4667 PF15700.5 EMG50488.1 - 1e-22 81.4 16.0 2.2e-12 47.6 5.3 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4667) Aminotran_1_2 PF00155.21 EMG50489.1 - 8.4e-39 133.8 0.0 1.1e-38 133.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMG50489.1 - 0.19 11.0 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EMG50489.1 - 0.21 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aldedh PF00171.22 EMG50490.1 - 1.4e-153 511.7 0.0 1.6e-153 511.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Arginase PF00491.21 EMG50493.1 - 1.4e-82 277.3 0.1 1.7e-82 277.1 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EMG50493.1 - 0.0048 17.1 0.3 0.009 16.3 0.3 1.6 1 1 0 1 1 1 1 UPF0489 domain HA2 PF04408.23 EMG50496.1 - 2.4e-16 59.9 2.0 2.9e-16 59.7 0.0 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMG50496.1 - 1.7e-14 54.1 0.1 6.1e-14 52.3 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMG50496.1 - 1.8e-14 53.9 0.1 5.5e-14 52.3 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EMG50496.1 - 5.3e-08 33.2 1.5 2.2e-07 31.3 0.0 2.6 2 1 1 3 3 3 1 AAA domain DEAD PF00270.29 EMG50496.1 - 6.5e-08 32.5 0.1 1.6e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EMG50496.1 - 0.00019 21.8 2.6 0.0015 18.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EMG50496.1 - 0.00034 20.3 0.3 0.0016 18.1 0.3 2.1 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 EMG50496.1 - 0.0021 17.2 0.0 0.004 16.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EMG50496.1 - 0.0027 17.5 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EMG50496.1 - 0.021 14.3 0.0 0.062 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EMG50496.1 - 0.043 13.9 4.5 1 9.4 0.1 3.9 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EMG50496.1 - 0.08 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Flavi_DEAD PF07652.14 EMG50496.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_16 PF13191.6 EMG50496.1 - 1 9.8 2.8 1.2 9.5 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain WSC PF01822.19 EMG50497.1 - 1.4e-09 38.0 12.0 1.4e-09 38.0 12.0 2.7 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.10 EMG50497.1 - 0.0062 15.9 0.1 0.021 14.3 0.1 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 EMG50497.1 - 0.011 15.3 0.3 0.025 14.2 0.0 1.7 2 0 0 2 2 2 0 CD34/Podocalyxin family Rick_17kDa_Anti PF05433.15 EMG50497.1 - 0.027 14.3 4.1 0.082 12.8 4.1 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain SPX PF03105.19 EMG50497.1 - 0.033 14.1 14.0 0.048 13.6 14.0 1.3 1 0 0 1 1 1 0 SPX domain PPP4R2 PF09184.11 EMG50497.1 - 0.12 11.9 7.8 0.19 11.3 7.8 1.3 1 0 0 1 1 1 0 PPP4R2 Yip1 PF04893.17 EMG50497.1 - 0.19 11.5 0.8 0.27 10.9 0.1 1.5 2 0 0 2 2 2 0 Yip1 domain GREB1 PF15782.5 EMG50497.1 - 2.9 4.9 14.0 3.6 4.6 14.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 EMG50497.1 - 6 5.9 24.4 8.2 5.5 24.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2370 PF10176.9 EMG50498.1 - 9.8e-83 277.2 0.4 1.9e-82 276.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) Mito_carr PF00153.27 EMG50499.1 - 1.3e-59 198.2 6.7 2.1e-21 75.7 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMG50499.1 - 0.00096 18.4 2.1 0.17 11.0 0.3 2.6 2 1 1 3 3 3 2 Gammaproteobacterial serine protease adh_short PF00106.25 EMG50500.1 - 3.7e-43 147.3 0.1 5.2e-43 146.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG50500.1 - 1.7e-34 119.4 0.0 2.2e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG50500.1 - 7.7e-10 39.0 0.1 9.8e-09 35.4 0.0 2.3 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.10 EMG50500.1 - 1.2e-06 28.2 0.0 9.9e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMG50500.1 - 0.00024 20.6 0.1 0.00069 19.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PRK PF00485.18 EMG50501.1 - 2.6e-59 200.3 0.1 8.4e-59 198.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EMG50501.1 - 3.2e-34 118.2 0.0 5e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 EMG50501.1 - 0.00063 20.3 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 EMG50501.1 - 0.00076 19.4 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KAP_NTPase PF07693.14 EMG50501.1 - 0.0046 16.2 0.0 0.0073 15.6 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain Zeta_toxin PF06414.12 EMG50501.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 EMG50501.1 - 0.027 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 EMG50501.1 - 0.036 14.2 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EMG50501.1 - 0.17 12.3 0.2 11 6.4 0.1 3.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMG50501.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Hyr1 PF15789.5 EMG50502.1 - 6.3 6.4 15.5 7.3 6.2 0.8 3.3 1 1 1 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 Asp-B-Hydro_N PF05279.11 EMG50503.1 - 6.7 6.7 32.9 11 6.0 32.9 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SNF5 PF04855.12 EMG50504.1 - 8.7e-46 156.6 0.5 1.4e-29 103.5 0.0 3.7 2 2 1 3 3 3 2 SNF5 / SMARCB1 / INI1 UPF0262 PF06793.12 EMG50504.1 - 0.52 10.4 2.3 0.86 9.7 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0262) DNA_pol_B PF00136.21 EMG50506.1 - 5.3e-120 401.2 6.9 8e-120 400.6 6.9 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EMG50506.1 - 1.7e-63 213.8 0.9 3.6e-63 212.7 0.9 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EMG50506.1 - 1.7e-42 145.8 0.1 7.1e-42 143.7 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EMG50506.1 - 7.6e-20 70.8 11.0 2.1e-19 69.4 11.0 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Peptidase_C36 PF05415.11 EMG50506.1 - 0.088 13.0 0.1 4.8 7.4 0.0 3.2 3 0 0 3 3 3 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase Pup PF05639.11 EMG50506.1 - 0.82 10.6 0.0 0.82 10.6 0.0 4.0 6 0 0 6 6 6 0 Pup-like protein Voltage_CLC PF00654.20 EMG50507.1 - 1.3e-13 51.0 5.8 1.4e-13 50.9 1.0 2.2 1 1 0 2 2 2 2 Voltage gated chloride channel AATase PF07247.12 EMG50508.1 - 1.9e-33 115.8 3.4 3.8e-33 114.8 3.4 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase DUF535 PF04393.13 EMG50508.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF535) Syntaxin_2 PF14523.6 EMG50510.1 - 2.3e-22 79.3 7.8 2.3e-22 79.3 7.8 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EMG50510.1 - 5.5e-16 58.3 0.8 1.3e-15 57.1 0.2 2.0 2 0 0 2 2 1 1 SNARE domain Syntaxin PF00804.25 EMG50510.1 - 1.1e-07 31.8 12.4 1.1e-07 31.8 12.4 1.6 2 0 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.21 EMG50510.1 - 0.00046 19.9 1.4 0.00046 19.9 1.4 2.6 3 0 0 3 3 3 1 Synaptobrevin MT PF12777.7 EMG50510.1 - 0.0097 15.0 0.2 0.0097 15.0 0.2 1.5 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor DUF1664 PF07889.12 EMG50510.1 - 0.071 13.1 9.5 1.5 8.9 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 EMG50510.1 - 0.078 12.8 8.9 0.5 10.2 1.8 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2757 PF10955.8 EMG50510.1 - 0.09 13.0 1.4 0.2 11.9 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2757) Use1 PF09753.9 EMG50510.1 - 0.098 12.4 0.3 0.098 12.4 0.3 2.7 1 1 2 3 3 3 0 Membrane fusion protein Use1 COG2 PF06148.11 EMG50510.1 - 0.11 12.5 5.0 0.74 9.9 0.4 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 S6PP_C PF08472.10 EMG50510.1 - 0.12 12.2 1.4 0.35 10.7 0.1 2.3 2 2 1 3 3 3 0 Sucrose-6-phosphate phosphohydrolase C-terminal Orf78 PF06024.12 EMG50510.1 - 0.21 11.9 0.2 0.21 11.9 0.2 3.0 2 1 0 2 2 1 0 Orf78 (ac78) SseC PF04888.12 EMG50510.1 - 0.26 10.9 6.6 0.97 9.0 6.0 2.1 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Med21 PF11221.8 EMG50510.1 - 0.5 10.6 15.6 0.45 10.8 0.7 2.9 2 1 0 2 2 2 0 Subunit 21 of Mediator complex TolA_bind_tri PF16331.5 EMG50510.1 - 0.92 9.6 18.8 0.086 12.9 3.4 3.9 3 1 1 4 4 4 0 TolA binding protein trimerisation CLZ PF16526.5 EMG50510.1 - 2.3 8.6 6.7 1.1 9.7 0.2 3.2 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LPP PF04728.13 EMG50510.1 - 3.3 8.2 10.5 5.1 7.6 1.1 3.5 3 1 1 4 4 4 0 Lipoprotein leucine-zipper Laminin_II PF06009.12 EMG50510.1 - 7.1 6.6 13.9 0.92 9.5 0.9 2.6 1 1 0 2 2 2 0 Laminin Domain II Voltage_CLC PF00654.20 EMG50511.1 - 1.3e-52 179.2 12.0 1.6e-52 178.9 12.0 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EMG50511.1 - 3e-14 53.2 0.4 6.6e-10 39.3 0.2 2.6 2 0 0 2 2 2 2 CBS domain CBF PF03914.17 EMG50512.1 - 4.6e-47 160.2 0.0 4.6e-47 160.2 0.0 4.9 4 2 0 4 4 4 1 CBF/Mak21 family Na_trans_assoc PF06512.13 EMG50512.1 - 0.011 16.1 0.9 0.011 16.1 0.9 5.0 3 2 1 4 4 4 0 Sodium ion transport-associated Cnd1 PF12717.7 EMG50512.1 - 1.3 9.0 9.0 0.061 13.4 1.0 2.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ATP-synt_C PF00137.21 EMG50513.1 - 4.9e-35 119.7 24.9 1.7e-22 79.6 13.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PIRT PF15099.6 EMG50513.1 - 0.56 9.8 2.1 0.45 10.1 0.5 1.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Tetraspanin PF00335.20 EMG50513.1 - 2.6 7.7 7.0 3.4 7.3 7.0 1.1 1 0 0 1 1 1 0 Tetraspanin family Ras PF00071.22 EMG50514.1 - 1.9e-19 69.9 0.1 4.6e-19 68.6 0.1 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EMG50514.1 - 0.00044 20.5 0.0 0.0036 17.5 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 EMG50515.1 - 2e-62 210.9 0.8 3.7e-62 210.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50515.1 - 2.2e-36 125.5 0.0 5.6e-36 124.1 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EMG50515.1 - 1.4e-19 69.7 33.1 3.1e-12 46.2 12.1 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 EMG50515.1 - 1.8e-17 63.2 22.9 4.3e-11 42.8 2.6 3.4 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 EMG50515.1 - 2.3e-13 50.6 1.3 1.1e-12 48.5 1.3 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EMG50515.1 - 0.00013 22.2 0.3 0.00032 21.0 0.3 1.6 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EMG50515.1 - 0.0037 16.6 0.1 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Uds1 PF15456.6 EMG50515.1 - 0.082 13.1 0.0 0.082 13.1 0.0 4.2 4 0 0 4 4 4 0 Up-regulated During Septation C1_2 PF03107.16 EMG50515.1 - 0.24 11.7 23.3 0.88 9.9 8.6 2.9 2 0 0 2 2 2 0 C1 domain zf-RING_9 PF13901.6 EMG50515.1 - 7.1 6.5 28.6 0.71 9.8 7.1 3.5 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon zinc_ribbon_16 PF17034.5 EMG50516.1 - 4.1e-33 114.3 14.7 1.2e-32 112.8 14.7 1.8 1 0 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 EMG50516.1 - 0.0065 17.3 0.1 0.16 12.9 0.0 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EMG50516.1 - 0.014 15.0 9.6 0.052 13.2 9.6 2.0 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type VID27 PF08553.10 EMG50516.1 - 0.014 14.5 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Mut7-C PF01927.16 EMG50516.1 - 0.41 10.7 5.2 0.9 9.6 0.3 2.5 2 0 0 2 2 2 0 Mut7-C RNAse domain DUF2757 PF10955.8 EMG50516.1 - 0.43 10.9 3.4 0.46 10.8 0.7 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2757) SUN PF03856.13 EMG50517.1 - 1.5e-77 260.4 8.2 1.8e-77 260.1 8.2 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF2235 PF09994.9 EMG50518.1 - 1.2e-78 264.4 0.0 1.7e-78 263.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Rieske PF00355.26 EMG50519.1 - 1.5e-11 44.0 0.0 2.6e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EMG50519.1 - 7.5e-09 35.9 0.5 1.3e-08 35.1 0.5 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region HECT PF00632.25 EMG50520.1 - 9e-86 288.1 1.0 1.5e-85 287.4 0.4 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) zf-LSD1 PF06943.12 EMG50520.1 - 0.0044 16.8 0.7 0.0089 15.8 0.7 1.5 1 0 0 1 1 1 1 LSD1 zinc finger DUF1645 PF07816.11 EMG50520.1 - 9.8 6.7 9.7 19 5.7 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Nucleopor_Nup85 PF07575.13 EMG50521.1 - 4.3e-77 260.0 9.4 7.4e-77 259.2 9.4 1.4 1 0 0 1 1 1 1 Nup85 Nucleoporin TEA PF01285.18 EMG50522.1 - 1.5e-26 92.2 0.0 3.1e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain Pkinase PF00069.25 EMG50523.1 - 1.8e-59 201.3 0.0 4.7e-59 199.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain zf-HC5HC2H_2 PF13832.6 EMG50523.1 - 1.5e-29 102.4 8.0 1.5e-29 102.4 8.0 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain Pkinase_Tyr PF07714.17 EMG50523.1 - 5.3e-27 94.7 0.0 1e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase zf-HC5HC2H PF13771.6 EMG50523.1 - 9.7e-27 93.1 5.3 9.7e-27 93.1 5.3 3.6 2 1 1 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.9 EMG50523.1 - 8.3e-18 65.3 6.9 8.2e-17 62.0 6.9 2.5 1 1 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.6 EMG50523.1 - 2.1e-14 52.8 2.1 7.8e-14 50.9 2.1 2.1 1 0 0 1 1 1 1 PHD-finger Kinase-like PF14531.6 EMG50523.1 - 1.3e-10 41.1 0.0 3.8e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like PHD PF00628.29 EMG50523.1 - 1.1e-08 34.8 9.9 1.1e-08 34.8 9.9 3.2 3 0 0 3 3 3 1 PHD-finger Pkinase_fungal PF17667.1 EMG50523.1 - 3e-05 23.0 0.0 7.3e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EMG50523.1 - 0.027 13.8 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RGS PF00615.19 EMG50524.1 - 3e-06 27.5 0.4 0.00027 21.2 0.0 2.7 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF2207 PF09972.9 EMG50524.1 - 8 5.1 8.1 26 3.4 8.1 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_L19e PF01280.20 EMG50525.1 - 1.5e-58 197.0 9.3 1.5e-58 197.0 9.3 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e DUF2423 PF10338.9 EMG50526.1 - 6.1e-16 58.4 8.1 6.1e-16 58.4 8.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Rgp1 PF08737.10 EMG50526.1 - 1.8 7.7 9.1 1.8 7.7 9.1 1.0 1 0 0 1 1 1 0 Rgp1 AIRC PF00731.20 EMG50527.1 - 3.1e-62 208.6 0.6 6.4e-62 207.5 0.6 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EMG50527.1 - 8.8e-61 204.4 0.0 1.3e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EMG50527.1 - 4.1e-17 61.6 0.0 8e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EMG50527.1 - 2.8e-07 30.2 0.0 5.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 EMG50527.1 - 0.00031 20.2 0.0 0.00066 19.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.13 EMG50527.1 - 0.0009 18.8 0.0 0.0048 16.5 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 EMG50527.1 - 0.00099 18.5 0.1 0.015 14.6 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ATP-grasp_3 PF02655.14 EMG50527.1 - 0.0085 16.1 0.0 0.028 14.5 0.0 1.9 2 1 0 2 2 2 1 ATP-grasp domain FAD_binding_2 PF00890.24 EMG50527.1 - 0.071 12.2 0.3 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain PP-binding PF00550.25 EMG50527.1 - 0.085 13.2 0.0 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 Phosphopantetheine attachment site Colicin_Ia PF11504.8 EMG50527.1 - 0.1 12.7 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Colicin Ia RRM_1 PF00076.22 EMG50528.1 - 8.9e-13 47.9 0.3 8.9e-13 47.9 0.3 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EMG50528.1 - 0.00057 20.4 0.5 0.00057 20.4 0.5 2.8 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.11 EMG50528.1 - 0.0012 18.9 2.3 0.0014 18.6 0.1 2.2 2 1 1 3 3 3 1 RNA binding motif Gloverin PF10793.9 EMG50528.1 - 0.016 15.1 0.2 0.027 14.3 0.2 1.4 1 0 0 1 1 1 0 Gloverin-like protein Na_H_antiport_2 PF13726.6 EMG50528.1 - 0.02 15.0 0.0 0.1 12.8 0.0 2.0 1 1 1 2 2 2 0 Na+-H+ antiporter family RRM_occluded PF16842.5 EMG50528.1 - 0.046 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif SPA PF08616.10 EMG50529.1 - 1.3e-33 115.3 0.2 4.4e-33 113.6 0.2 2.0 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EMG50529.1 - 2.2e-23 83.2 0.1 5e-23 82.1 0.1 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EMG50529.1 - 2.3e-16 59.5 1.3 7.3e-12 44.7 0.0 2.6 2 1 0 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.9 EMG50529.1 - 0.00012 21.8 1.0 0.0045 16.6 0.4 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 EMG50529.1 - 0.047 13.6 4.3 3.6 7.5 0.3 3.5 4 0 0 4 4 4 0 DENN (AEX-3) domain SOCS_box PF07525.16 EMG50529.1 - 0.14 12.5 1.3 0.28 11.6 0.1 2.1 2 0 0 2 2 2 0 SOCS box zf-C2H2 PF00096.26 EMG50531.1 - 0.0037 17.6 10.3 0.0055 17.1 0.5 4.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG50531.1 - 0.015 16.1 0.6 0.015 16.1 0.6 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger Macoilin PF09726.9 EMG50531.1 - 0.33 9.5 10.8 0.45 9.0 10.8 1.3 1 0 0 1 1 1 0 Macoilin family DUF4512 PF14975.6 EMG50531.1 - 2.3 9.1 5.0 1.4e+02 3.3 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) Pap_E4 PF02711.14 EMG50531.1 - 8.8 7.4 19.0 1 10.3 13.4 2.3 2 1 1 3 3 3 0 E4 protein Mito_carr PF00153.27 EMG50532.1 - 5.9e-47 157.5 6.6 6.5e-17 61.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4011 PF13195.6 EMG50532.1 - 0.046 13.6 0.2 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) WASH-7_mid PF14744.6 EMG50532.1 - 0.098 11.7 1.9 2.2 7.3 0.1 2.7 3 0 0 3 3 3 0 WASH complex subunit 7 CDP-OH_P_tran_2 PF08009.11 EMG50532.1 - 1.6 8.7 10.0 2.5 8.1 0.1 3.5 3 0 0 3 3 3 0 CDP-alcohol phosphatidyltransferase 2 AAA PF00004.29 EMG50533.1 - 2.8e-43 147.5 0.2 1.5e-42 145.1 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DnaJ PF00226.31 EMG50533.1 - 5.9e-20 71.2 4.4 2e-19 69.4 4.4 2.0 1 0 0 1 1 1 1 DnaJ domain AAA_lid_3 PF17862.1 EMG50533.1 - 4.4e-14 52.0 0.0 9.5e-14 50.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EMG50533.1 - 5.7e-07 29.8 0.1 2.4e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EMG50533.1 - 1.3e-06 28.5 0.0 3.9e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 EMG50533.1 - 2.6e-05 24.1 0.7 5.5e-05 23.0 0.7 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EMG50533.1 - 5.1e-05 23.7 0.1 0.00056 20.3 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EMG50533.1 - 0.00024 21.4 4.1 0.021 15.1 0.6 3.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EMG50533.1 - 0.00037 20.3 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EMG50533.1 - 0.00085 19.9 0.2 0.028 15.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EMG50533.1 - 0.0035 17.1 0.7 0.0081 15.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 EMG50533.1 - 0.0072 16.5 0.0 0.0072 16.5 0.0 2.6 4 0 0 4 4 2 1 AAA domain TIP49 PF06068.13 EMG50533.1 - 0.0076 15.5 0.1 0.031 13.5 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 EMG50533.1 - 0.01 16.1 1.0 0.035 14.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EMG50533.1 - 0.021 14.3 0.1 0.21 11.0 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 EMG50533.1 - 0.023 14.6 0.0 0.08 12.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMG50533.1 - 0.024 15.0 0.0 0.16 12.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase TPR_8 PF13181.6 EMG50533.1 - 0.024 14.8 6.9 2.8 8.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_14 PF13173.6 EMG50533.1 - 0.025 14.6 0.2 0.14 12.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 EMG50533.1 - 0.027 14.5 0.0 0.091 12.8 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EMG50533.1 - 0.037 13.4 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EMG50533.1 - 0.11 12.1 0.0 0.38 10.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain CSN5_C PF18323.1 EMG50533.1 - 0.61 11.0 4.0 7 7.6 0.0 2.9 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain AAA_11 PF13086.6 EMG50533.1 - 1.4 8.7 8.3 2.1 8.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain Hydin_ADK PF17213.3 EMG50533.1 - 7.2 6.8 6.4 51 4.1 0.0 3.0 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Peptidase_M28 PF04389.17 EMG50534.1 - 3.3e-38 131.4 0.1 4.8e-38 130.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMG50534.1 - 6.2e-11 42.2 0.1 1.7e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EMG50534.1 - 0.0005 19.8 0.0 0.00099 18.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EMG50534.1 - 0.049 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Pyrophosphatase PF00719.19 EMG50535.1 - 6.8e-58 195.0 0.1 1.3e-57 194.1 0.1 1.5 1 0 0 1 1 1 1 Inorganic pyrophosphatase TP6A_N PF04406.14 EMG50535.1 - 1.6e-06 28.0 0.2 3.2e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase CDKN3 PF05706.12 EMG50535.1 - 0.12 12.0 0.2 0.24 11.1 0.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) RCR PF12273.8 EMG50536.1 - 3.9e-39 134.0 4.1 3.9e-39 134.0 4.1 2.4 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF2167 PF09935.9 EMG50536.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Ac110_PIF PF07280.11 EMG50536.1 - 0.16 11.7 0.7 0.25 11.1 0.7 1.3 1 0 0 1 1 1 0 Per os infectivity factor AC110 LIM_bind PF01803.16 EMG50537.1 - 9.8e-56 189.0 1.2 9.8e-56 189.0 1.2 4.6 4 1 1 5 5 5 1 LIM-domain binding protein PAPA-1 PF04795.12 EMG50537.1 - 1.2e-11 45.2 8.1 1.2e-11 45.2 8.1 3.8 4 0 0 4 4 4 1 PAPA-1-like conserved region Response_reg PF00072.24 EMG50538.1 - 0.052 13.7 1.0 4.4 7.5 0.0 3.1 2 1 1 3 3 3 0 Response regulator receiver domain ProRS-C_1 PF09180.11 EMG50538.1 - 0.092 13.0 2.9 3.8 7.8 0.2 3.8 3 1 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal HisK_sensor PF18698.1 EMG50538.1 - 0.15 12.5 6.4 4.6 7.6 0.2 3.5 3 0 0 3 3 3 0 Histidine kinase sensor domain 2OG-Fe_Oxy_2 PF10014.9 EMG50538.1 - 0.81 9.5 4.1 13 5.5 0.1 3.7 2 2 2 4 4 4 0 2OG-Fe dioxygenase cNMP_binding PF00027.29 EMG50538.1 - 2.5 8.2 10.8 0.54 10.4 0.5 4.5 4 2 1 5 5 5 0 Cyclic nucleotide-binding domain YopH_N PF09013.10 EMG50538.1 - 6.5 7.0 8.7 3.6 7.9 1.1 3.2 2 2 1 3 3 3 0 YopH, N-terminal Pkinase PF00069.25 EMG50540.1 - 1.9e-72 243.8 0.1 1.2e-71 241.1 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50540.1 - 2.7e-34 118.6 0.0 1.2e-33 116.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG50540.1 - 0.014 14.2 0.2 0.046 12.5 0.2 2.0 1 1 0 1 1 1 0 Fungal protein kinase T2SSG PF08334.11 EMG50540.1 - 0.13 12.3 6.1 0.071 13.2 2.6 2.3 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein G Scm3 PF10384.9 EMG50541.1 - 2.6 7.9 7.8 1.3 8.8 0.1 2.9 3 0 0 3 3 3 0 Centromere protein Scm3 MIF4G PF02854.19 EMG50542.1 - 5.6e-42 143.8 1.0 5.6e-42 143.8 1.0 2.1 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 EMG50542.1 - 9.9e-23 80.1 0.2 4.1e-22 78.1 0.2 2.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 AFT PF08731.11 EMG50543.1 - 1.5e-27 96.2 7.4 1.5e-27 96.2 7.4 5.4 5 2 0 5 5 5 1 Transcription factor AFT Nramp PF01566.18 EMG50544.1 - 1.7e-88 297.0 16.9 2.4e-53 181.4 6.6 2.3 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Ca_hom_mod PF14798.6 EMG50544.1 - 0.18 10.9 2.5 0.14 11.2 0.2 1.9 2 0 0 2 2 2 0 Calcium homeostasis modulator HAD PF12710.7 EMG50545.1 - 1.1e-28 101.0 0.0 1.4e-28 100.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EMG50545.1 - 3.2e-05 23.6 0.0 0.00015 21.4 0.0 1.9 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 EMG50545.1 - 0.00055 19.4 0.3 0.0083 15.6 0.1 2.0 2 0 0 2 2 2 1 Putative Phosphatase Ish1 PF10281.9 EMG50545.1 - 0.089 13.1 0.0 5.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Ribosomal_L12 PF00542.19 EMG50546.1 - 7.9e-23 80.6 5.3 7.9e-23 80.6 5.3 2.2 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EMG50546.1 - 7.5e-16 57.6 1.2 1.8e-15 56.3 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain BLYB PF05289.11 EMG50547.1 - 0.048 13.9 1.2 0.12 12.6 0.9 1.8 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein TFIIS_C PF01096.18 EMG50548.1 - 5.1e-16 58.2 15.5 2.2e-14 53.0 6.1 3.0 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EMG50548.1 - 1.1e-14 54.0 3.8 1.1e-14 54.0 3.8 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 EMG50548.1 - 0.0006 19.8 9.9 0.0062 16.5 0.7 2.4 2 1 0 2 2 2 2 Double zinc ribbon Ogr_Delta PF04606.12 EMG50548.1 - 0.066 13.2 10.7 0.13 12.2 2.7 2.6 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-UBP PF02148.19 EMG50548.1 - 0.082 13.2 6.8 3.9 7.9 0.2 2.5 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Nudix_N_2 PF14803.6 EMG50548.1 - 0.097 12.6 0.8 0.097 12.6 0.8 3.0 3 0 0 3 3 3 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 EMG50548.1 - 0.16 12.1 12.1 8.5 6.6 0.2 3.9 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_13 PF09855.9 EMG50548.1 - 0.24 11.6 0.2 0.24 11.6 0.2 3.3 2 2 1 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn_ribbon_recom PF13408.6 EMG50548.1 - 0.34 11.5 6.1 0.3 11.6 0.5 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain C1_4 PF07975.12 EMG50548.1 - 0.37 11.1 13.9 11 6.4 0.8 3.5 2 2 1 3 3 3 0 TFIIH C1-like domain zinc_ribbon_10 PF10058.9 EMG50548.1 - 0.39 10.5 13.3 1.4 8.7 1.9 2.7 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ACC PF17848.1 EMG50548.1 - 0.44 10.7 0.1 0.44 10.7 0.1 4.3 5 0 0 5 5 5 0 Acetyl-coA carboxylase zinc finger domain zf-GRF PF06839.12 EMG50548.1 - 3.4 7.8 10.4 0.36 11.0 0.4 3.1 3 0 0 3 3 3 0 GRF zinc finger zf-C4_Topoisom PF01396.19 EMG50548.1 - 4 7.3 14.0 0.66 9.8 1.1 2.6 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Pkinase PF00069.25 EMG50549.1 - 4.7e-73 245.8 0.0 8.5e-73 245.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50549.1 - 1.6e-39 135.8 0.0 2.7e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG50549.1 - 2.1e-05 24.0 0.7 5.6e-05 22.6 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EMG50549.1 - 0.00032 19.8 5.5 0.00053 19.0 5.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 EMG50549.1 - 0.043 13.3 0.3 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL TFIIA PF03153.13 EMG50549.1 - 0.34 10.9 15.7 0.42 10.6 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EMG50549.1 - 0.38 9.4 8.3 0.49 9.0 8.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 EMG50549.1 - 1.4 7.3 11.2 1.7 7.0 11.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Mcm10 PF09332.11 EMG50549.1 - 3.5 7.0 12.9 5.9 6.2 12.9 1.3 1 0 0 1 1 1 0 Mcm10 replication factor Presenilin PF01080.17 EMG50549.1 - 6.8 5.3 9.6 9.5 4.9 9.6 1.1 1 0 0 1 1 1 0 Presenilin Fungal_trans PF04082.18 EMG50550.1 - 1.6e-14 53.6 2.0 2.6e-14 52.9 1.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG50550.1 - 4.1e-10 39.6 13.5 7.8e-10 38.7 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1912 PF08930.10 EMG50550.1 - 0.06 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) PAC2 PF09754.9 EMG50551.1 - 1.1e-22 81.1 0.1 1.8e-22 80.4 0.1 1.4 1 1 0 1 1 1 1 PAC2 family TFIIS_C PF01096.18 EMG50552.1 - 1.4e-18 66.4 1.9 1.4e-18 66.4 1.9 2.8 4 0 0 4 4 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EMG50552.1 - 1.5e-08 34.3 8.4 3.6e-05 23.6 0.3 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 EMG50552.1 - 6.7e-05 22.8 7.5 0.039 14.0 0.3 2.7 2 1 0 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.6 EMG50552.1 - 0.0011 18.3 14.1 0.38 10.2 1.2 4.0 3 1 0 3 3 3 2 zinc-ribbon domain C1_1 PF00130.22 EMG50552.1 - 0.0024 17.7 3.5 0.21 11.5 0.2 2.4 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C4_Topoisom PF01396.19 EMG50552.1 - 0.0025 17.5 5.3 0.019 14.7 3.5 3.0 2 1 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger Lar_restr_allev PF14354.6 EMG50552.1 - 0.0026 18.1 4.1 0.12 12.7 0.7 2.4 2 0 0 2 2 2 1 Restriction alleviation protein Lar zf-TFIIB PF13453.6 EMG50552.1 - 0.0033 16.7 0.7 0.0086 15.4 0.7 1.7 1 0 0 1 1 1 1 Transcription factor zinc-finger Baculo_LEF5_C PF11792.8 EMG50552.1 - 0.004 16.8 3.3 0.11 12.2 0.0 2.8 3 0 0 3 3 2 1 Baculoviridae late expression factor 5 C-terminal domain TF_Zn_Ribbon PF08271.12 EMG50552.1 - 0.0059 16.1 12.2 0.032 13.7 3.7 3.0 2 2 0 2 2 2 2 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 EMG50552.1 - 0.0075 16.0 15.7 0.27 11.0 0.3 3.8 3 1 0 3 3 3 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EMG50552.1 - 0.0086 16.2 9.4 3.4 7.9 0.1 3.3 3 0 0 3 3 3 1 Zinc ribbon domain Ogr_Delta PF04606.12 EMG50552.1 - 0.021 14.8 4.9 0.021 14.8 4.9 2.2 2 2 0 2 2 1 0 Ogr/Delta-like zinc finger DUF523 PF04463.12 EMG50552.1 - 0.027 14.5 0.2 0.032 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF523) zinc_ribbon_4 PF13717.6 EMG50552.1 - 0.036 14.0 7.6 6.9 6.7 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.19 EMG50552.1 - 0.042 13.9 7.4 0.36 10.9 3.4 2.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_7 PF02591.15 EMG50552.1 - 0.044 14.0 3.8 28 5.0 0.0 3.9 4 0 0 4 4 4 0 C4-type zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 EMG50552.1 - 0.044 13.8 7.7 0.099 12.6 2.1 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-RRN7 PF11781.8 EMG50552.1 - 0.059 13.1 10.1 10 5.9 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 IBR PF01485.21 EMG50552.1 - 0.061 13.6 6.5 0.53 10.5 1.5 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 EMG50552.1 - 0.11 13.0 7.5 0.66 10.5 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain GATA PF00320.27 EMG50552.1 - 0.11 12.2 3.3 0.3 10.7 0.6 2.6 2 1 0 2 2 2 0 GATA zinc finger Ribosomal_S26e PF01283.19 EMG50552.1 - 0.14 12.6 1.1 0.6 10.6 0.2 2.3 2 1 0 2 2 2 0 Ribosomal protein S26e DUF3268 PF11672.8 EMG50552.1 - 0.17 12.3 4.8 0.59 10.5 1.1 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain OrfB_Zn_ribbon PF07282.11 EMG50552.1 - 0.19 11.7 7.5 5.8 6.9 2.8 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF2072 PF09845.9 EMG50552.1 - 0.19 12.0 6.3 0.44 10.8 0.1 2.8 1 1 2 3 3 3 0 Zn-ribbon containing protein Elf1 PF05129.13 EMG50552.1 - 0.31 11.1 8.3 0.56 10.3 0.7 2.9 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like DpnI PF06044.12 EMG50552.1 - 0.32 10.6 5.3 2.8 7.5 0.4 2.1 1 1 0 2 2 2 0 Dam-replacing family PADR1 PF08063.12 EMG50552.1 - 0.6 9.9 6.6 1.7 8.5 0.2 2.9 3 0 0 3 3 3 0 PADR1 (NUC008) domain Nop10p PF04135.12 EMG50552.1 - 0.61 10.2 4.5 1 9.4 2.4 2.6 2 1 0 2 2 1 0 Nucleolar RNA-binding protein, Nop10p family A2L_zn_ribbon PF08792.10 EMG50552.1 - 1.1 9.1 11.5 24 4.8 0.2 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain Stc1 PF12898.7 EMG50552.1 - 1.3 9.6 7.2 1.5 9.4 0.4 2.4 1 1 1 2 2 2 0 Stc1 domain zf-RING_5 PF14634.6 EMG50552.1 - 1.3 9.0 6.6 7.5 6.6 1.0 2.9 3 0 0 3 3 3 0 zinc-RING finger domain Mu-like_Com PF10122.9 EMG50552.1 - 1.6 8.2 4.3 2.1 7.9 0.1 2.8 2 1 1 3 3 3 0 Mu-like prophage protein Com RecR PF02132.15 EMG50552.1 - 1.7 8.3 9.5 0.4 10.3 0.6 3.0 3 0 0 3 3 3 0 RecR protein zf-HIT PF04438.16 EMG50552.1 - 2 8.3 13.9 9 6.3 0.8 4.0 4 0 0 4 4 4 0 HIT zinc finger DUF3716 PF12511.8 EMG50552.1 - 2.5 8.2 8.3 0.12 12.4 1.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) zinc_ribbon_15 PF17032.5 EMG50552.1 - 2.6 8.9 11.2 27 5.6 7.0 3.0 1 1 1 3 3 3 0 zinc-ribbon family CpXC PF14353.6 EMG50552.1 - 2.6 8.1 9.4 0.92 9.6 0.1 3.0 1 1 2 3 3 3 0 CpXC protein Zn_Tnp_IS91 PF14319.6 EMG50552.1 - 3 7.9 8.2 3.4 7.8 2.0 2.8 1 1 1 2 2 2 0 Transposase zinc-binding domain UPF0547 PF10571.9 EMG50552.1 - 3.6 7.7 10.1 13 6.0 0.3 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-Mss51 PF13824.6 EMG50552.1 - 6.6 6.9 10.4 3.4 7.8 2.8 3.0 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_RNApol_7kD PF03604.13 EMG50552.1 - 7.3 6.4 12.1 7 6.4 0.9 3.9 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_recom PF13408.6 EMG50552.1 - 8.4 7.0 13.0 4.1 8.0 2.0 3.3 2 2 1 3 3 3 0 Recombinase zinc beta ribbon domain Nudix_N_2 PF14803.6 EMG50552.1 - 8.5 6.4 11.6 3.3 7.7 1.3 3.4 3 1 0 3 3 2 0 Nudix N-terminal zf-C2H2 PF00096.26 EMG50552.1 - 8.6 7.0 14.8 0.84 10.2 1.7 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type HEAT_2 PF13646.6 EMG50553.1 - 5.9e-31 106.7 0.5 1.6e-14 54.0 0.1 3.3 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 EMG50553.1 - 3.8e-22 76.7 0.4 2.6e-06 27.6 0.0 6.7 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 EMG50553.1 - 2.6e-14 52.1 0.1 0.078 13.3 0.0 5.7 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.6 EMG50553.1 - 1.1e-07 32.2 0.3 0.4 11.2 0.0 5.0 5 1 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 EMG50553.1 - 0.032 14.3 0.7 12 5.9 0.0 3.5 2 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EMG50553.1 - 0.047 13.7 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 EMG50553.1 - 0.059 13.7 0.2 1.4 9.3 0.1 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF438 PF04282.13 EMG50553.1 - 0.1 12.5 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF438) Macro PF01661.21 EMG50554.1 - 1.9e-32 111.7 0.2 3.7e-32 110.8 0.2 1.5 1 0 0 1 1 1 1 Macro domain YdjO PF14169.6 EMG50554.1 - 0.1 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO Flavin_Reduct PF01613.18 EMG50555.1 - 3e-20 72.8 0.0 4.2e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DHquinase_II PF01220.19 EMG50556.1 - 5.2e-57 191.4 0.4 5.8e-57 191.2 0.4 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Dioxygenase_C PF00775.21 EMG50557.1 - 1.2e-44 152.0 0.0 1.7e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EMG50557.1 - 6.8e-28 96.3 0.1 1.3e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EMG50557.1 - 0.00081 19.6 0.0 0.0022 18.2 0.0 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain ACOX PF01756.19 EMG50557.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA oxidase CoA_trans PF01144.23 EMG50558.1 - 5.9e-97 323.3 0.9 5.4e-57 192.7 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 EMG50558.1 - 0.0056 15.1 0.0 0.1 10.9 0.0 2.0 2 0 0 2 2 2 2 Malonate decarboxylase, alpha subunit, transporter UPF0052 PF01933.18 EMG50558.1 - 0.13 11.4 0.2 0.23 10.6 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Epimerase PF01370.21 EMG50559.1 - 4.5e-27 95.1 0.0 6.2e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG50559.1 - 1e-14 54.2 0.0 1.4e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMG50559.1 - 9.9e-13 48.2 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EMG50559.1 - 2.9e-12 46.3 0.0 1e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EMG50559.1 - 1.3e-10 41.5 0.0 3.8e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EMG50559.1 - 4.4e-07 29.7 0.6 1.4e-05 24.7 0.1 2.5 1 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EMG50559.1 - 2.8e-05 23.7 0.0 6.8e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMG50559.1 - 9.5e-05 22.4 0.0 0.00046 20.1 0.0 2.2 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EMG50559.1 - 0.0004 19.6 0.0 0.00064 18.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 EMG50559.1 - 0.011 16.3 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMG50559.1 - 0.024 14.7 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 EMG50559.1 - 0.033 13.7 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 EMG50559.1 - 0.042 13.0 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Cpn60_TCP1 PF00118.24 EMG50560.1 - 4.5e-156 520.3 3.3 5.1e-156 520.1 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Epimerase PF01370.21 EMG50561.1 - 2.7e-17 63.1 0.0 3.4e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG50561.1 - 9e-16 57.7 0.0 1.3e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMG50561.1 - 4.6e-12 45.6 0.0 5.3e-11 42.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EMG50561.1 - 6.5e-08 32.7 0.1 3.1e-07 30.5 0.1 2.0 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMG50561.1 - 2.1e-06 27.4 0.0 2.9e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EMG50561.1 - 0.00047 19.7 0.0 0.00087 18.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMG50561.1 - 0.00089 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EMG50561.1 - 0.003 17.2 0.1 0.0081 15.7 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EMG50561.1 - 0.0034 16.6 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 EMG50561.1 - 0.074 13.6 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMG50561.1 - 0.086 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EMG50562.1 - 4e-18 65.8 0.0 5.3e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG50562.1 - 1.1e-12 47.5 0.0 1.8e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMG50562.1 - 5.3e-08 32.4 0.0 1.8e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EMG50562.1 - 3.2e-07 30.4 0.0 8.8e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMG50562.1 - 5.1e-05 22.8 0.0 0.00011 21.8 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EMG50562.1 - 0.0003 20.3 0.0 0.00096 18.7 0.0 1.9 3 0 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EMG50562.1 - 0.0058 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EMG50562.1 - 0.0061 16.1 0.0 0.44 10.1 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family Retro_M PF02813.14 EMG50562.1 - 0.071 13.5 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral M domain DUF1771 PF08590.10 EMG50563.1 - 2.3e-20 72.7 11.5 3.9e-20 72.0 11.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EMG50563.1 - 1.6e-10 41.2 2.4 3.7e-10 40.0 0.2 2.3 2 0 0 2 2 2 1 Smr domain Seryl_tRNA_N PF02403.22 EMG50563.1 - 0.014 15.6 5.6 0.028 14.7 5.6 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Peptidase_M3_N PF08439.10 EMG50563.1 - 0.085 13.1 1.1 0.29 11.4 0.9 1.9 1 1 1 2 2 2 0 Oligopeptidase F PMC2NT PF08066.12 EMG50563.1 - 0.18 12.5 2.1 0.5 11.1 1.4 2.3 1 1 0 1 1 1 0 PMC2NT (NUC016) domain Cep57_MT_bd PF06657.13 EMG50563.1 - 0.37 11.3 6.4 0.71 10.4 6.4 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 HJURP_C PF12347.8 EMG50563.1 - 0.42 10.7 6.9 0.53 10.4 2.0 2.4 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Basic PF01586.16 EMG50563.1 - 2.4 9.4 5.1 1.3 10.2 2.6 2.0 2 0 0 2 2 2 0 Myogenic Basic domain DUF883 PF05957.13 EMG50563.1 - 5.5 7.7 6.8 16 6.2 6.8 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF3484 PF11983.8 EMG50563.1 - 9.6 7.4 11.5 0.68 11.1 3.8 2.5 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Ras PF00071.22 EMG50564.1 - 1.1e-51 174.7 0.3 1.3e-51 174.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG50564.1 - 5.1e-35 120.3 0.2 7.3e-35 119.8 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG50564.1 - 2.7e-17 62.8 0.1 3.2e-17 62.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMG50564.1 - 5.9e-09 35.6 0.2 7.5e-09 35.3 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EMG50564.1 - 8.2e-08 32.0 0.2 1.8e-06 27.6 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMG50564.1 - 2.7e-07 30.7 0.0 4.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMG50564.1 - 1.6e-06 28.2 0.2 0.024 14.6 0.1 2.5 1 1 2 3 3 3 2 RsgA GTPase ATP_bind_1 PF03029.17 EMG50564.1 - 2.2e-05 24.4 0.3 0.0016 18.3 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EMG50564.1 - 0.00048 19.6 0.1 0.00073 19.0 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EMG50564.1 - 0.00099 18.9 0.2 0.006 16.3 0.1 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EMG50564.1 - 0.0012 19.1 0.0 0.016 15.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EMG50564.1 - 0.004 17.1 0.2 0.057 13.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EMG50564.1 - 0.0049 16.8 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EMG50564.1 - 0.0058 16.6 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 EMG50564.1 - 0.0077 16.0 0.1 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMG50564.1 - 0.008 16.6 0.0 0.0091 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 EMG50564.1 - 0.0086 15.4 0.4 0.017 14.4 0.2 1.6 2 0 0 2 2 2 1 Septin AAA_7 PF12775.7 EMG50564.1 - 0.014 14.9 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 EMG50564.1 - 0.022 13.9 0.1 0.033 13.4 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 EMG50564.1 - 0.03 14.4 0.2 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EMG50564.1 - 0.031 13.7 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 EMG50564.1 - 0.036 13.2 4.7 0.28 10.3 4.7 2.2 1 1 0 1 1 1 0 G-protein alpha subunit MCM PF00493.23 EMG50564.1 - 0.065 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain NTPase_1 PF03266.15 EMG50564.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 NTPase cobW PF02492.19 EMG50564.1 - 0.083 12.5 0.6 0.19 11.3 0.1 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EMG50564.1 - 0.091 13.2 0.1 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 EMG50564.1 - 0.14 12.6 0.9 0.19 12.2 0.9 1.6 1 1 0 1 1 1 0 ABC transporter MCM PF00493.23 EMG50565.1 - 2.5e-95 317.8 0.3 3.8e-95 317.2 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMG50565.1 - 1.6e-31 108.8 0.0 3.7e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EMG50565.1 - 2.8e-25 88.6 0.5 6.3e-25 87.4 0.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMG50565.1 - 7.9e-15 55.3 0.1 3.5e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMG50565.1 - 1.4e-07 31.2 0.0 1.1e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EMG50565.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMG50565.1 - 0.0022 17.7 0.0 0.0072 16.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 EMG50565.1 - 0.058 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arc_PepC PF06819.11 EMG50565.1 - 0.11 12.7 0.7 0.57 10.3 0.0 2.5 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain AAA PF00004.29 EMG50565.1 - 0.18 12.2 1.0 0.42 11.0 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CBF PF03914.17 EMG50566.1 - 1.8e-30 106.2 3.1 2.4e-30 105.8 1.9 1.9 2 0 0 2 2 2 1 CBF/Mak21 family DUF5009 PF16401.5 EMG50566.1 - 0.016 14.7 0.1 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5009) ATP-synt PF00231.19 EMG50566.1 - 0.091 12.5 0.5 0.17 11.6 0.5 1.4 1 0 0 1 1 1 0 ATP synthase FAT PF02259.23 EMG50567.1 - 6.4e-142 472.8 6.1 6.4e-142 472.8 6.1 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EMG50567.1 - 4.4e-70 236.4 0.0 9.1e-70 235.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EMG50567.1 - 9e-66 220.7 14.8 8.4e-61 204.6 1.1 6.9 6 1 0 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EMG50567.1 - 2.9e-42 143.1 4.6 7.1e-42 141.8 1.5 3.1 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 EMG50567.1 - 6.9e-17 61.0 0.3 1.6e-16 59.8 0.3 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 EMG50567.1 - 3.3e-12 45.5 5.7 0.0026 17.9 0.0 8.7 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 EMG50567.1 - 6.2e-12 45.8 1.3 0.055 13.9 0.0 7.9 9 1 0 9 9 6 2 HEAT repeats HEAT_EZ PF13513.6 EMG50567.1 - 1.1e-08 35.4 11.6 0.00045 20.7 0.0 8.4 8 1 1 9 9 7 2 HEAT-like repeat CLASP_N PF12348.8 EMG50567.1 - 1.7e-07 31.0 1.3 0.34 10.4 0.0 5.1 5 1 0 5 5 5 3 CLASP N terminal IFRD PF05004.13 EMG50567.1 - 7.8e-07 28.5 1.5 0.01 14.9 0.1 4.0 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 EMG50567.1 - 1e-06 28.9 4.7 0.12 12.4 0.1 4.4 3 0 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 EMG50567.1 - 0.00012 22.5 0.0 4.9 7.7 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Cnd3 PF12719.7 EMG50567.1 - 0.0029 16.9 0.1 0.14 11.3 0.0 3.5 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain TPR_14 PF13428.6 EMG50567.1 - 0.013 16.2 0.0 1.8 9.6 0.0 4.3 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF1104 PF06518.11 EMG50567.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF1104) PRAS PF15798.5 EMG50567.1 - 0.2 12.2 0.4 0.58 10.8 0.2 1.8 2 0 0 2 2 1 0 Proline-rich AKT1 substrate 1 SUIM_assoc PF16619.5 EMG50567.1 - 2.2 8.4 9.2 6.3 6.9 9.2 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TPR_2 PF07719.17 EMG50567.1 - 3.7 7.9 5.9 15 6.0 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Actin PF00022.19 EMG50568.1 - 9.7e-90 301.1 0.0 2.3e-87 293.3 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 EMG50568.1 - 0.0007 20.0 0.0 0.0029 18.0 0.0 2.1 2 1 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 EMG50568.1 - 0.0029 16.5 0.0 0.13 11.1 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein STD1 PF17235.2 EMG50569.1 - 2e-48 164.8 1.8 2e-48 164.8 1.8 1.6 2 0 0 2 2 2 1 STD1/MTH1 DUF498 PF04430.14 EMG50570.1 - 9.9e-19 67.4 0.0 1.5e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DUF3090 PF11290.8 EMG50571.1 - 0.091 12.6 0.4 9 6.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) Pil1 PF13805.6 EMG50572.1 - 5.1e-125 416.3 0.3 7.1e-125 415.8 0.3 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 RasGEF PF00617.19 EMG50573.1 - 7.1e-39 133.8 0.1 7.1e-39 133.8 0.1 2.7 4 0 0 4 4 4 1 RasGEF domain RasGEF_N PF00618.20 EMG50573.1 - 1.7e-10 41.0 4.4 1.7e-10 41.0 4.4 3.3 3 0 0 3 3 3 1 RasGEF N-terminal motif Ribosomal_L5_C PF00673.21 EMG50574.1 - 1.9e-21 76.1 0.0 2.8e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EMG50574.1 - 1.2e-19 70.4 0.1 5.3e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 EMG50574.1 - 0.077 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Proteasome PF00227.26 EMG50575.1 - 1.5e-45 155.0 0.1 2.9e-45 154.1 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit Forkhead PF00250.18 EMG50575.1 - 4.1e-16 59.0 0.4 1.5e-15 57.2 0.4 2.0 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EMG50575.1 - 2.6e-10 40.5 0.3 6.4e-10 39.2 0.3 1.7 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 EMG50575.1 - 0.053 13.8 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 FHA domain Cellulase PF00150.18 EMG50576.1 - 9.7e-07 28.5 4.8 1.5e-05 24.6 4.8 2.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SLX9 PF15341.6 EMG50577.1 - 3.2e-17 63.2 16.6 3.2e-17 63.2 16.6 2.0 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 DUF87 PF01935.17 EMG50577.1 - 3.6 7.6 9.0 2.8 8.0 7.6 1.4 1 1 1 2 2 2 0 Helicase HerA, central domain Cu_amine_oxid PF01179.20 EMG50579.1 - 4.9e-155 516.5 0.0 5.8e-155 516.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cofilin_ADF PF00241.20 EMG50580.1 - 1.8e-30 105.2 0.1 9.5e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Asparaginase PF00710.20 EMG50580.1 - 0.016 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Asparaginase, N-terminal PolyG_pol PF01518.16 EMG50580.1 - 0.052 12.2 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma NS protein Csm2_III-A PF03750.13 EMG50580.1 - 0.1 13.5 0.1 19 6.1 0.0 3.0 2 1 1 3 3 3 0 Csm2 Type III-A zf-RING_2 PF13639.6 EMG50581.1 - 1.3e-08 35.1 30.1 3.5e-08 33.6 9.8 2.4 2 0 0 2 2 2 2 Ring finger domain PHD PF00628.29 EMG50581.1 - 0.0015 18.4 13.5 0.0015 18.4 13.5 3.1 2 1 1 3 3 3 1 PHD-finger PHD_2 PF13831.6 EMG50581.1 - 0.0052 16.3 7.6 0.0052 16.3 7.6 2.6 3 0 0 3 3 3 1 PHD-finger zf-C3HC4_3 PF13920.6 EMG50581.1 - 0.025 14.4 27.0 0.044 13.6 8.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SR-25 PF10500.9 EMG50581.1 - 1.1 8.9 17.3 6.5 6.3 12.8 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Zn-C2H2_12 PF18112.1 EMG50581.1 - 5.2 7.6 7.4 4.1 7.9 0.2 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-rbx1 PF12678.7 EMG50581.1 - 8.2 6.8 25.5 0.89 9.9 7.5 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger domain BCAS2 PF05700.11 EMG50582.1 - 1.8e-13 50.7 14.4 4.3e-12 46.2 14.4 2.1 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) MAGUK_N_PEST PF10608.9 EMG50582.1 - 0.22 11.9 2.4 0.62 10.5 2.4 1.8 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK RICH PF05062.12 EMG50582.1 - 0.28 11.6 4.5 0.78 10.1 1.0 2.5 1 1 1 2 2 2 0 RICH domain SH3_1 PF00018.28 EMG50583.1 - 6.2e-05 22.5 0.0 0.00031 20.3 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EMG50583.1 - 0.0041 16.9 0.0 0.047 13.5 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain NOA36 PF06524.12 EMG50583.1 - 0.35 10.1 41.0 0.4 10.0 7.4 2.8 2 0 0 2 2 2 0 NOA36 protein Aminotran_1_2 PF00155.21 EMG50584.1 - 1.9e-74 251.0 0.0 2.2e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Rxt3 PF08642.10 EMG50585.1 - 1.4e-24 87.3 0.1 1.4e-24 87.3 0.1 3.9 2 2 0 2 2 2 1 Histone deacetylation protein Rxt3 SelP_N PF04592.14 EMG50585.1 - 0.61 9.4 32.8 1.2 8.5 32.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAM60A PF15396.6 EMG50585.1 - 9 6.2 11.0 1.9 8.5 6.2 2.0 1 1 1 2 2 2 0 Protein Family FAM60A Aminotran_3 PF00202.21 EMG50586.1 - 4.9e-82 275.7 0.1 5.6e-82 275.6 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EMG50586.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DUF1746 PF08508.10 EMG50587.1 - 5.4e-30 104.1 0.7 7.6e-30 103.6 0.7 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RNA_pol_A_bac PF01000.26 EMG50588.1 - 3.1e-26 91.9 0.0 5.8e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EMG50588.1 - 4.9e-20 70.7 0.0 6.7e-20 70.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Prot_ATP_OB_N PF17758.1 EMG50588.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain KCNQ2_u3 PF16642.5 EMG50589.1 - 0.029 15.4 4.6 0.029 15.4 4.6 5.9 5 1 1 6 6 6 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Pkinase PF00069.25 EMG50590.1 - 2.5e-40 138.5 0.0 1.6e-21 76.8 0.0 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50590.1 - 1.3e-15 57.4 0.0 1.2e-11 44.4 0.0 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EMG50590.1 - 0.0083 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EMP24_GP25L PF01105.24 EMG50591.1 - 1.5e-49 168.5 2.1 3.8e-49 167.1 2.1 1.7 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Bot1p PF12298.8 EMG50591.1 - 5.1e-44 150.5 0.3 9.3e-44 149.6 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF2569 PF10754.9 EMG50591.1 - 0.07 13.6 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) PIG-P PF08510.12 EMG50592.1 - 8.5e-35 119.3 4.4 1e-34 119.0 4.4 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EMG50592.1 - 0.00016 21.9 4.0 0.00024 21.4 4.0 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) HEAT_EZ PF13513.6 EMG50593.1 - 2.2e-20 72.7 0.0 1.8e-10 41.1 0.0 6.6 6 2 0 6 6 6 3 HEAT-like repeat HEAT PF02985.22 EMG50593.1 - 4.7e-16 57.5 6.7 0.018 15.3 0.0 11.3 13 0 0 13 13 13 2 HEAT repeat HEAT_2 PF13646.6 EMG50593.1 - 1.2e-12 48.0 0.0 0.0038 17.6 0.0 7.8 7 1 2 9 9 9 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EMG50593.1 - 2e-06 28.3 0.8 0.023 15.3 0.0 5.0 5 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 EMG50593.1 - 0.0002 21.2 1.2 0.003 17.4 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.7 EMG50593.1 - 0.00024 21.2 8.9 0.04 14.0 0.0 5.6 3 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 BP28CT PF08146.12 EMG50593.1 - 0.095 12.5 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 BP28CT (NUC211) domain Arm PF00514.23 EMG50593.1 - 0.4 10.8 9.3 0.84 9.8 0.0 5.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Xpo1 PF08389.12 EMG50593.1 - 0.79 9.8 12.3 1.8 8.6 4.7 4.8 3 2 1 4 4 4 0 Exportin 1-like protein MFAP1 PF06991.11 EMG50593.1 - 0.96 9.3 3.7 1.8 8.4 3.7 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Ribosomal_L28 PF00830.19 EMG50594.1 - 7.2e-12 45.3 1.2 1.8e-11 44.1 1.1 1.7 2 0 0 2 2 2 1 Ribosomal L28 family DHR-2 PF06920.13 EMG50595.1 - 6.7e-38 130.6 4.7 2.1e-37 129.0 4.7 1.8 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 EMG50595.1 - 1e-15 57.6 0.0 1e-14 54.3 0.0 2.4 2 1 0 2 2 2 1 DOCK N-terminus FANCI_S4 PF14678.6 EMG50595.1 - 0.04 13.0 0.1 0.088 11.9 0.1 1.5 1 0 0 1 1 1 0 FANCI solenoid 4 AA_permease PF00324.21 EMG50596.1 - 1.7e-77 261.0 48.6 4.8e-76 256.3 48.6 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG50596.1 - 3.8e-25 88.6 42.0 6.8e-25 87.8 42.0 1.4 1 1 0 1 1 1 1 Amino acid permease YmcE_antitoxin PF15939.5 EMG50596.1 - 0.4 10.9 2.3 0.97 9.6 0.4 2.5 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system DUF1640 PF07798.11 EMG50597.1 - 1.9e-31 109.4 4.4 1.9e-31 109.4 4.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Ubie_methyltran PF01209.18 EMG50598.1 - 1.5e-88 296.1 0.0 1.7e-88 295.9 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EMG50598.1 - 1.8e-12 47.8 0.0 3.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG50598.1 - 1.8e-10 41.3 0.0 3.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMG50598.1 - 5.6e-10 39.2 0.0 8.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG50598.1 - 1.4e-09 38.6 0.0 2.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMG50598.1 - 5.1e-05 23.2 0.0 7.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EMG50598.1 - 0.077 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase CAP_N PF01213.19 EMG50598.1 - 0.15 11.5 1.8 0.22 11.0 1.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PK PF00224.21 EMG50599.1 - 5.9e-173 574.6 3.5 7.6e-173 574.2 3.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EMG50599.1 - 1.1e-36 125.7 0.1 3.2e-36 124.1 0.1 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EMG50599.1 - 0.00027 20.1 0.8 0.00048 19.3 0.2 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Pam16 PF03656.13 EMG50600.1 - 1.6e-05 25.0 0.8 0.00011 22.2 0.8 2.2 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 EMG50600.1 - 0.00015 21.8 0.1 0.00044 20.3 0.1 1.8 1 1 0 1 1 1 1 DnaJ domain NEMO PF11577.8 EMG50600.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO AAA PF00004.29 EMG50601.1 - 2.9e-56 189.5 0.0 3.9e-43 147.0 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMG50601.1 - 5.3e-12 45.3 1.0 9e-06 25.4 0.1 3.5 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 EMG50601.1 - 5e-06 27.0 0.0 0.028 14.8 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EMG50601.1 - 1.1e-05 25.2 0.0 0.0013 18.5 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EMG50601.1 - 8.4e-05 22.8 0.0 0.0061 16.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 EMG50601.1 - 0.00029 20.8 0.1 0.22 11.5 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 EMG50601.1 - 0.00038 19.6 0.0 0.00081 18.6 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 EMG50601.1 - 0.0012 19.2 0.0 0.013 15.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase TFIIE_beta PF02186.15 EMG50601.1 - 0.0018 18.5 1.1 0.056 13.7 0.3 3.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain Vps4_C PF09336.10 EMG50601.1 - 0.0039 17.1 0.2 0.041 13.9 0.1 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 EMG50601.1 - 0.004 16.7 0.0 0.023 14.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EMG50601.1 - 0.0044 17.3 0.4 0.049 13.9 0.0 2.8 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EMG50601.1 - 0.0057 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 EMG50601.1 - 0.0065 15.9 0.0 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.6 EMG50601.1 - 0.0071 16.4 0.0 0.45 10.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMG50601.1 - 0.0093 16.1 0.0 0.52 10.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 EMG50601.1 - 0.0093 15.2 0.0 0.027 13.7 0.0 1.8 1 0 0 1 1 1 1 TIP49 P-loop domain NB-ARC PF00931.22 EMG50601.1 - 0.011 15.0 0.0 3.3 6.8 0.0 3.4 3 0 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.14 EMG50601.1 - 0.013 15.5 0.0 0.068 13.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EMG50601.1 - 0.016 15.8 0.2 0.13 12.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EMG50601.1 - 0.017 14.5 0.0 0.045 13.1 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EMG50601.1 - 0.02 14.6 0.0 0.56 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMG50601.1 - 0.041 13.4 0.3 0.67 9.5 0.0 2.9 3 1 1 4 4 3 0 AAA domain AAA_28 PF13521.6 EMG50601.1 - 0.053 13.8 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EMG50601.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein MEA1 PF06910.11 EMG50601.1 - 0.1 13.2 0.1 0.6 10.7 0.0 2.4 2 0 0 2 2 2 0 Male enhanced antigen 1 (MEA1) NACHT PF05729.12 EMG50601.1 - 0.14 12.1 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Ribosomal_L31e PF01198.19 EMG50602.1 - 4.8e-38 129.3 1.4 5.7e-38 129.0 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Ribosomal_L36e PF01158.18 EMG50605.1 - 2.3e-36 123.9 8.1 2.5e-36 123.8 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF4050 PF13259.6 EMG50606.1 - 9.9e-15 55.3 10.0 4.1e-13 50.1 1.7 3.8 2 2 1 3 3 3 2 Protein of unknown function (DUF4050) ArfGap PF01412.18 EMG50606.1 - 0.54 10.4 3.1 21 5.2 0.2 3.0 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf FemAB PF02388.16 EMG50607.1 - 0.033 13.1 3.0 0.046 12.6 3.0 1.2 1 0 0 1 1 1 0 FemAB family DUF2393 PF09624.10 EMG50607.1 - 0.3 11.1 0.1 0.3 11.1 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2393) Pex14_N PF04695.13 EMG50607.1 - 0.41 11.3 8.1 0.35 11.5 5.7 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med1 PF10744.9 EMG50608.1 - 1.8e-74 251.3 6.5 2.3e-74 250.9 3.6 2.6 2 1 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 EF-hand_3 PF09069.11 EMG50608.1 - 0.0046 17.3 0.1 0.29 11.6 0.0 2.9 1 1 0 2 2 2 1 EF-hand IF-2B PF01008.17 EMG50609.1 - 3.7e-59 200.3 4.0 2.7e-58 197.4 4.0 1.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family ABC_sub_bind PF04392.12 EMG50609.1 - 0.0015 17.9 0.2 0.0015 17.9 0.2 2.0 2 0 0 2 2 2 1 ABC transporter substrate binding protein Fes1 PF08609.10 EMG50609.1 - 7.2 7.6 7.7 1.5 9.8 2.4 2.2 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 HSP20 PF00011.21 EMG50610.1 - 0.0084 16.2 0.1 0.053 13.7 0.1 1.9 2 0 0 2 2 2 1 Hsp20/alpha crystallin family LRR_4 PF12799.7 EMG50611.1 - 1.3e-33 114.5 48.6 1.3e-09 38.2 1.8 7.3 4 2 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMG50611.1 - 1.9e-20 72.4 41.0 2.9e-06 27.0 2.3 6.8 3 2 2 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 EMG50611.1 - 1.1e-17 64.1 25.2 2.9e-08 33.4 4.0 3.9 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 EMG50611.1 - 0.0026 18.0 34.8 5.6 7.9 0.4 9.2 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 EMG50611.1 - 0.003 17.5 30.9 0.2 11.8 1.1 7.9 9 0 0 9 9 9 3 Leucine Rich repeat LRR_2 PF07723.13 EMG50611.1 - 2 9.2 7.0 31 5.5 0.1 4.7 6 1 0 6 6 6 0 Leucine Rich Repeat PP-binding PF00550.25 EMG50612.1 - 7.8e-11 42.2 0.4 1.1e-10 41.7 0.4 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EMG50612.1 - 3.6e-05 23.9 0.5 9.9e-05 22.5 0.4 1.6 1 1 1 2 2 2 1 Acyl-carrier HAMP PF00672.25 EMG50612.1 - 0.2 12.1 1.1 0.51 10.8 0.0 2.1 2 0 0 2 2 2 0 HAMP domain DHR-2 PF06920.13 EMG50613.1 - 5.2e-35 121.1 5.1 1.5e-24 86.5 0.0 3.3 2 1 1 3 3 3 2 Dock homology region 2 DOCK_N PF16172.5 EMG50613.1 - 1.7e-06 27.3 0.1 3.2e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 DOCK N-terminus Clathrin PF00637.20 EMG50613.1 - 0.061 13.2 1.9 0.27 11.1 0.1 2.8 2 0 0 2 2 2 0 Region in Clathrin and VPS SWI-SNF_Ssr4 PF08549.10 EMG50614.1 - 0.0076 14.9 0.0 0.0076 14.9 0.0 2.7 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1750) Phosphodiest PF01663.22 EMG50615.1 - 2.5e-13 50.4 0.4 3.9e-13 49.7 0.4 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EMG50615.1 - 0.00018 21.0 0.3 0.00029 20.3 0.3 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EMG50615.1 - 0.00039 19.9 0.4 0.0008 18.9 0.1 1.6 2 0 0 2 2 2 1 Sulfatase YkyA PF10368.9 EMG50615.1 - 1.1 8.8 3.9 0.27 10.9 0.5 1.7 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Glyco_hydro_47 PF01532.20 EMG50616.1 - 3.6e-117 392.1 0.2 4.5e-117 391.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF835 PF05763.12 EMG50616.1 - 0.065 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF835) DUF3445 PF11927.8 EMG50617.1 - 7.8e-65 218.7 0.1 9.3e-65 218.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) adh_short PF00106.25 EMG50618.1 - 7.3e-47 159.4 0.0 9.9e-47 158.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG50618.1 - 5.4e-34 117.8 0.0 6.9e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG50618.1 - 2.3e-10 40.7 0.0 4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMG50618.1 - 1.7e-07 30.9 0.0 3.1e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMG50618.1 - 0.00036 20.1 0.0 0.00089 18.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMG50618.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase GRDP-like PF07173.12 EMG50619.1 - 1.7e-24 87.1 1.4 3e-21 76.6 0.2 3.7 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like Pkinase PF00069.25 EMG50620.1 - 5.1e-67 226.0 0.0 1.3e-66 224.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50620.1 - 3.7e-28 98.5 0.0 5.9e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EMG50620.1 - 2.8e-11 43.9 0.3 1.3e-10 41.7 0.3 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EMG50620.1 - 2.1e-09 37.6 0.1 7.3e-07 29.4 0.0 3.1 3 0 0 3 3 3 1 C2 domain Kinase-like PF14531.6 EMG50620.1 - 4.3e-09 36.1 0.0 3.2e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EMG50620.1 - 0.00079 19.1 0.1 0.079 12.6 0.0 2.5 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EMG50620.1 - 0.0016 17.5 0.1 0.0016 17.5 0.1 2.4 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EMG50620.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-met PF12874.7 EMG50621.1 - 1.1e-05 25.6 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EMG50621.1 - 0.00047 20.4 0.0 0.00086 19.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EMG50621.1 - 0.0076 16.7 0.1 0.015 15.7 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG50621.1 - 0.053 14.4 0.0 0.11 13.4 0.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger TPX2 PF06886.11 EMG50621.1 - 0.065 13.5 17.2 0.11 12.7 17.2 1.4 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) zf-C2H2_9 PF16293.5 EMG50621.1 - 0.067 13.0 0.2 0.16 11.8 0.2 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 EMG50621.1 - 0.13 12.7 1.2 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Pro_isomerase PF00160.21 EMG50623.1 - 1.4e-46 158.7 0.1 1.8e-46 158.3 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD adh_short PF00106.25 EMG50624.1 - 8e-46 156.0 0.0 1.1e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMG50624.1 - 8.4e-36 123.7 0.0 3.4e-35 121.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG50624.1 - 1e-10 41.8 0.0 2e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMG50624.1 - 2.3e-08 33.8 0.0 2.8e-07 30.2 0.0 2.2 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMG50624.1 - 0.00015 21.3 0.0 0.00034 20.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMG50624.1 - 0.0012 18.3 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF658 PF04936.12 EMG50624.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) Lin-8 PF03353.15 EMG50625.1 - 0.0075 15.9 21.1 0.0099 15.5 21.1 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist TMF_DNA_bd PF12329.8 EMG50625.1 - 0.01 15.8 12.2 0.01 15.8 12.2 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TMEM192 PF14802.6 EMG50625.1 - 0.023 13.8 1.4 0.041 13.0 1.4 1.4 1 0 0 1 1 1 0 TMEM192 family MAGSP PF03082.14 EMG50625.1 - 0.16 11.5 9.5 0.055 13.1 0.8 2.1 2 0 0 2 2 2 0 Male accessory gland secretory protein AF-4 PF05110.13 EMG50625.1 - 0.94 7.5 37.4 1 7.4 37.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PilJ PF13675.6 EMG50625.1 - 1.2 9.2 4.9 0.44 10.6 0.8 2.1 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term FliD_N PF02465.18 EMG50625.1 - 4.7 8.0 15.5 0.31 11.7 4.6 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ribosomal_S8 PF00410.19 EMG50626.1 - 6.3e-10 39.1 0.1 2.7e-09 37.0 0.1 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 PNK3P PF08645.11 EMG50628.1 - 7.4e-12 45.3 0.1 1.6e-11 44.2 0.1 1.6 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase Aminotran_1_2 PF00155.21 EMG50629.1 - 1.9e-05 24.0 0.0 2.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 EMG50630.1 - 7.3e-34 117.2 39.1 3e-21 75.8 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG50630.1 - 1.7e-06 27.2 41.3 1.4e-05 24.2 5.3 3.8 3 1 1 4 4 4 3 Sugar (and other) transporter Novirhabdo_Nv PF05554.11 EMG50630.1 - 0.014 15.1 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein MFS_1 PF07690.16 EMG50631.1 - 2.5e-32 112.2 8.4 2.5e-32 112.2 8.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMG50631.1 - 8.2e-10 38.1 0.2 8.2e-10 38.1 0.2 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EMG50631.1 - 9.9e-06 24.2 0.3 1.5e-05 23.6 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EMG50631.1 - 9e-05 21.2 0.8 9e-05 21.2 0.8 4.0 2 2 3 5 5 5 2 MFS/sugar transport protein Aminotran_1_2 PF00155.21 EMG50633.1 - 0.00011 21.6 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4509 PF14970.6 EMG50633.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Sec1 PF00995.23 EMG50634.1 - 5.7e-61 207.4 20.6 7.3e-61 207.1 20.6 1.1 1 0 0 1 1 1 1 Sec1 family ATP-synt_E_2 PF08112.11 EMG50634.1 - 0.0056 16.9 0.6 5.2 7.4 0.1 3.3 2 0 0 2 2 2 2 ATP synthase epsilon subunit PS_pyruv_trans PF04230.13 EMG50634.1 - 0.018 15.0 3.3 0.54 10.1 0.1 3.0 3 0 0 3 3 3 0 Polysaccharide pyruvyl transferase 4HBT_3 PF13622.6 EMG50635.1 - 4.4e-32 112.3 0.0 8.4e-32 111.4 0.0 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMG50635.1 - 4.2e-09 36.3 0.1 6.9e-06 25.9 0.1 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase DUF3246 PF11596.8 EMG50635.1 - 0.15 11.5 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) 4HBT_3 PF13622.6 EMG50636.1 - 2.9e-30 106.3 0.0 6e-30 105.3 0.0 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMG50636.1 - 4.2e-17 62.2 0.8 3.8e-12 46.2 0.5 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase DUF1674 PF07896.12 EMG50637.1 - 1.3e-16 60.8 1.1 4.3e-16 59.1 1.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) PI-PLC-X PF00388.19 EMG50638.1 - 7.3e-19 67.8 0.0 1.4e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Zip PF02535.22 EMG50639.1 - 1.4e-75 254.6 1.3 1.6e-75 254.4 1.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Ion_trans PF00520.31 EMG50639.1 - 0.0086 15.3 0.2 0.49 9.6 0.0 2.5 2 1 0 2 2 2 1 Ion transport protein UNC-50 PF05216.13 EMG50639.1 - 0.019 14.5 1.5 0.49 9.9 0.8 2.2 2 0 0 2 2 2 0 UNC-50 family DUF3951 PF13131.6 EMG50639.1 - 0.1 12.8 1.7 0.17 12.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Iso_dh PF00180.20 EMG50640.1 - 5.5e-73 246.1 0.0 6.4e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-RING_5 PF14634.6 EMG50641.1 - 7.2e-09 35.5 4.3 1.2e-08 34.7 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Filament PF00038.21 EMG50641.1 - 0.0053 16.4 0.9 0.0053 16.4 0.9 1.5 2 0 0 2 2 2 1 Intermediate filament protein BLOC1_2 PF10046.9 EMG50641.1 - 0.013 15.8 5.3 0.22 11.8 1.2 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-MIZ PF02891.20 EMG50641.1 - 0.032 14.0 1.9 0.12 12.2 1.9 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DUF4618 PF15397.6 EMG50641.1 - 0.035 13.5 2.5 0.054 12.9 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) HR1 PF02185.16 EMG50641.1 - 0.042 14.0 0.9 0.13 12.3 0.9 1.9 1 0 0 1 1 1 0 Hr1 repeat zf-RING_UBOX PF13445.6 EMG50641.1 - 0.042 13.9 1.6 0.051 13.6 0.6 1.7 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EMG50641.1 - 0.051 13.4 8.0 0.37 10.7 8.0 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Phage_GP20 PF06810.11 EMG50641.1 - 0.052 13.4 2.4 0.064 13.1 0.6 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 POLO_box PF00659.18 EMG50641.1 - 0.08 13.1 0.5 1.8 8.8 0.1 3.0 2 0 0 2 2 2 0 POLO box duplicated region LPP PF04728.13 EMG50641.1 - 0.13 12.7 0.9 15 6.0 0.2 2.7 1 1 1 2 2 2 0 Lipoprotein leucine-zipper GIDA_assoc PF13932.6 EMG50641.1 - 0.21 11.8 2.6 0.21 11.8 0.9 1.9 1 1 1 2 2 2 0 GidA associated domain Med28 PF11594.8 EMG50641.1 - 0.22 11.6 2.3 17 5.5 0.1 2.8 2 1 0 2 2 2 0 Mediator complex subunit 28 Nefa_Nip30_N PF10187.9 EMG50641.1 - 0.26 11.7 2.8 16 5.9 0.5 2.3 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Golgin_A5 PF09787.9 EMG50641.1 - 0.51 9.7 5.1 0.12 11.8 0.4 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 zf-RING_2 PF13639.6 EMG50641.1 - 0.51 10.7 4.9 1.2 9.6 4.9 1.7 1 1 0 1 1 1 0 Ring finger domain Pox_A_type_inc PF04508.12 EMG50641.1 - 0.6 10.1 2.4 3.7 7.6 2.4 2.4 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat zf-C3HC4_3 PF13920.6 EMG50641.1 - 0.95 9.4 4.4 4.1 7.3 4.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMG50641.1 - 1.1 9.2 4.7 2.2 8.2 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TMF_DNA_bd PF12329.8 EMG50641.1 - 1.7 8.7 6.8 15 5.7 6.8 2.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding COX7C PF02935.16 EMG50643.1 - 1.7e-25 89.0 4.0 2.2e-25 88.7 4.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Calici_coat PF00915.20 EMG50643.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein TFIIA PF03153.13 EMG50645.1 - 0.69 9.8 35.7 0.56 10.2 28.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RFC1 PF08519.12 EMG50647.1 - 1.2e-53 181.4 1.9 1.2e-53 181.4 1.9 3.4 3 1 1 5 5 5 1 Replication factor RFC1 C terminal domain AAA PF00004.29 EMG50647.1 - 6.5e-11 42.8 0.6 3.8e-10 40.3 0.0 2.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 EMG50647.1 - 1e-10 41.8 4.0 2e-10 40.9 0.0 3.6 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 EMG50647.1 - 1.1e-05 25.5 1.5 3.2e-05 23.9 0.0 2.6 2 1 1 3 3 3 1 Rad17 P-loop domain ERM PF00769.19 EMG50647.1 - 2.5e-05 24.2 62.6 0.013 15.3 30.0 3.7 2 1 1 3 3 3 3 Ezrin/radixin/moesin family GRAB PF10375.9 EMG50647.1 - 4.9e-05 23.0 1.0 0.00012 21.8 1.0 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Lebercilin PF15619.6 EMG50647.1 - 0.00035 20.3 22.2 0.00035 20.3 22.2 5.0 5 1 1 6 6 4 1 Ciliary protein causing Leber congenital amaurosis disease RuvB_N PF05496.12 EMG50647.1 - 0.00072 19.3 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Spc7 PF08317.11 EMG50647.1 - 0.0025 16.7 24.0 0.0025 16.7 24.0 4.5 2 1 2 4 4 4 1 Spc7 kinetochore protein AAA_16 PF13191.6 EMG50647.1 - 0.0028 18.0 0.0 0.0028 18.0 0.0 3.3 3 1 0 3 3 1 1 AAA ATPase domain DUF5082 PF16888.5 EMG50647.1 - 0.0049 17.1 23.3 0.0049 17.1 23.3 4.7 2 1 2 4 4 4 1 Domain of unknown function (DUF5082) TPR_MLP1_2 PF07926.12 EMG50647.1 - 0.005 16.9 9.1 0.005 16.9 9.1 5.1 4 1 1 5 5 4 3 TPR/MLP1/MLP2-like protein AAA_assoc_2 PF16193.5 EMG50647.1 - 0.01 16.2 0.0 0.14 12.5 0.0 3.1 2 0 0 2 2 2 0 AAA C-terminal domain AAA_5 PF07728.14 EMG50647.1 - 0.016 15.2 2.9 1.1 9.2 0.0 3.5 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EMG50647.1 - 0.025 15.1 0.0 0.025 15.1 0.0 3.7 3 1 0 3 3 1 0 AAA domain AAA_33 PF13671.6 EMG50647.1 - 0.038 14.1 0.0 0.27 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EMG50647.1 - 0.15 12.3 2.9 0.19 12.0 0.0 2.8 3 1 0 3 3 2 0 AAA domain Golgin_A5 PF09787.9 EMG50647.1 - 0.87 9.0 63.9 0.069 12.6 20.8 4.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 FtsH_ext PF06480.15 EMG50647.1 - 0.9 9.9 9.3 0.19 12.1 1.0 3.3 1 1 1 2 2 2 0 FtsH Extracellular NPV_P10 PF05531.12 EMG50647.1 - 1.7 9.1 29.5 8.1 7.0 0.6 5.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.11 EMG50647.1 - 1.8 8.4 42.1 0.012 15.5 9.7 4.3 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) AAA_17 PF13207.6 EMG50647.1 - 1.9 8.9 0.0 1.9 8.9 0.0 4.4 5 1 1 6 6 5 0 AAA domain DUF2722 PF10846.8 EMG50648.1 - 4.8e-119 398.4 72.9 2.8e-70 237.6 35.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2722) DUF2870 PF11069.8 EMG50648.1 - 1.9 9.0 6.5 2.9 8.3 2.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) SHQ1 PF04925.15 EMG50650.1 - 2.2e-69 232.5 1.9 3.1e-69 232.1 1.9 1.2 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 EMG50650.1 - 0.034 14.5 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 PIH1 CS-like domain Diphthamide_syn PF01866.17 EMG50651.1 - 2.4e-113 378.6 0.1 3.1e-113 378.2 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF1241 PF06840.11 EMG50651.1 - 0.067 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) COG6 PF06419.11 EMG50652.1 - 1.1e-126 423.6 27.9 1.1e-84 284.9 11.4 2.6 2 1 1 3 3 3 2 Conserved oligomeric complex COG6 ADH_zinc_N_2 PF13602.6 EMG50653.1 - 1.1e-17 65.3 0.0 2e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMG50653.1 - 4.4e-12 46.1 0.0 8.6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG50653.1 - 1.1e-05 25.2 0.0 0.0001 22.1 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EMG50653.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase THF_DHG_CYH_C PF02882.19 EMG50653.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Nop53 PF07767.11 EMG50654.1 - 1.2e-90 304.8 47.5 1.5e-90 304.5 47.5 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4140 PF13600.6 EMG50654.1 - 0.0044 17.4 11.2 0.46 11.0 3.6 2.9 2 1 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) Baculo_LEF-11 PF06385.12 EMG50654.1 - 0.046 14.2 0.1 0.046 14.2 0.1 2.8 3 2 1 4 4 4 0 Baculovirus LEF-11 protein bZIP_1 PF00170.21 EMG50654.1 - 0.62 10.2 21.4 0.43 10.7 18.1 2.5 2 0 0 2 2 2 0 bZIP transcription factor MWFE PF15879.5 EMG50655.1 - 2.8e-22 78.6 0.2 4.2e-22 78.1 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Zn_clus PF00172.18 EMG50656.1 - 0.00019 21.5 8.9 0.0003 20.8 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EMG50657.1 - 1.9e-62 211.1 0.0 2.5e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50657.1 - 8.5e-40 136.7 0.0 1.1e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG50657.1 - 2e-07 30.6 0.0 4.6e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMG50657.1 - 0.00039 19.3 0.1 0.001 18.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EMG50657.1 - 0.00061 18.9 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EMG50657.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EMG50657.1 - 0.011 15.4 0.1 0.049 13.3 0.1 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EMG50657.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EMG50657.1 - 0.041 13.8 0.0 0.16 11.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EMG50657.1 - 0.076 11.9 0.0 0.076 11.9 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Epimerase PF01370.21 EMG50658.1 - 1.6e-20 73.6 0.0 2.7e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG50658.1 - 3.2e-17 62.4 0.1 5.5e-17 61.7 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMG50658.1 - 3.3e-13 49.4 0.0 1e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EMG50658.1 - 9.7e-12 45.2 0.1 1.8e-11 44.3 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMG50658.1 - 5.7e-09 35.8 0.0 8e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMG50658.1 - 5.9e-06 26.0 1.7 3.9e-05 23.3 0.4 2.3 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EMG50658.1 - 2.7e-05 23.7 0.1 0.00044 19.8 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMG50658.1 - 3.4e-05 23.8 0.0 7.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMG50658.1 - 3.5e-05 23.1 0.5 6e-05 22.3 0.5 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EMG50658.1 - 0.0024 17.0 0.0 0.0053 15.9 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain DapB_N PF01113.20 EMG50658.1 - 0.0065 16.6 0.1 0.015 15.4 0.1 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short_C2 PF13561.6 EMG50658.1 - 0.016 14.8 0.1 0.053 13.1 0.1 1.9 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase DUF4886 PF16227.5 EMG50658.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) COG4 PF08318.12 EMG50659.1 - 2.4e-90 303.0 3.4 2.4e-90 303.0 3.4 2.2 3 0 0 3 3 3 1 COG4 transport protein WRNPLPNID PF15017.6 EMG50659.1 - 4.5 8.2 10.2 14 6.6 10.2 1.9 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box zf-CCCH PF00642.24 EMG50660.1 - 1.1e-15 57.1 33.7 5.4e-05 23.0 1.5 5.8 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EMG50660.1 - 7.7e-14 51.2 45.9 2.6e-06 27.3 4.1 5.5 6 0 0 6 6 6 5 Zinc finger domain Torus PF16131.5 EMG50660.1 - 7.9e-12 45.8 22.8 0.00044 20.9 1.3 5.0 1 1 4 5 5 5 4 Torus domain zf-CCCH_3 PF15663.5 EMG50660.1 - 6.7e-09 35.9 19.8 5.8e-07 29.7 7.5 3.2 1 1 2 3 3 3 3 Zinc-finger containing family zf-CCCH_4 PF18044.1 EMG50660.1 - 6.1e-07 29.1 1.0 6.1e-07 29.1 1.0 4.8 5 0 0 5 5 5 4 CCCH-type zinc finger FAD_binding_2 PF00890.24 EMG50661.1 - 1.8e-73 248.1 0.0 2e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMG50661.1 - 2.3e-11 43.9 0.0 2.7e-08 33.8 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMG50661.1 - 2.8e-10 39.9 0.7 2.3e-06 27.0 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMG50661.1 - 1.4e-08 34.9 0.0 5.3e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMG50661.1 - 3.9e-08 32.4 1.3 0.0011 17.7 0.0 3.9 4 0 0 4 4 4 3 HI0933-like protein Thi4 PF01946.17 EMG50661.1 - 4.1e-07 29.5 0.6 0.016 14.5 0.0 2.4 2 0 0 2 2 2 2 Thi4 family FAD_oxidored PF12831.7 EMG50661.1 - 3.5e-06 26.6 0.1 1.2e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EMG50661.1 - 0.00052 19.2 0.0 0.0077 15.4 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EMG50661.1 - 0.0063 15.9 0.0 0.033 13.5 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EMG50661.1 - 0.0083 15.4 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EMG50661.1 - 0.014 14.5 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 EMG50661.1 - 0.1 11.9 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 EMG50661.1 - 0.11 11.8 0.6 3 7.0 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L35Ae PF01247.18 EMG50662.1 - 2.3e-40 136.7 0.5 2.6e-40 136.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EMG50662.1 - 0.018 15.2 0.0 2.6 8.3 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain Oxysterol_BP PF01237.18 EMG50663.1 - 5.9e-65 219.5 5.8 1e-62 212.2 5.8 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein GWT1 PF06423.12 EMG50664.1 - 1.6e-39 135.4 10.1 1.6e-39 135.4 10.1 3.1 3 1 0 3 3 3 1 GWT1 DUF4818 PF16089.5 EMG50664.1 - 0.029 14.8 0.0 0.21 12.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4818) CNDH2_N PF06278.11 EMG50664.1 - 0.04 14.1 0.4 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Spo7 PF03907.13 EMG50665.1 - 1.2e-65 221.1 3.7 1.2e-65 221.1 3.7 1.8 2 0 0 2 2 2 1 Spo7-like protein rve PF00665.26 EMG50665.1 - 0.001 19.3 0.0 0.0032 17.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain eIF3_subunit PF08597.10 EMG50665.1 - 2.1 8.2 12.9 0.015 15.2 1.9 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit ADH_zinc_N_2 PF13602.6 EMG50666.1 - 2.2e-18 67.6 0.0 3.6e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMG50666.1 - 9.8e-12 45.0 0.0 2e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG50666.1 - 7.4e-06 25.8 0.0 8.2e-05 22.4 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EMG50666.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase THF_DHG_CYH_C PF02882.19 EMG50666.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CTP_transf_3 PF02348.19 EMG50666.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase zf-CSL PF05207.13 EMG50667.1 - 5.3e-22 77.3 0.7 6.7e-22 77.0 0.7 1.1 1 0 0 1 1 1 1 CSL zinc finger Prok-RING_1 PF14446.6 EMG50667.1 - 0.41 10.6 3.1 0.77 9.7 3.1 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Ribosomal_S8e PF01201.22 EMG50668.1 - 2.4e-56 189.7 1.2 2.9e-56 189.5 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e NAD_binding_9 PF13454.6 EMG50668.1 - 0.09 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding GATase PF00117.28 EMG50669.1 - 1.1e-06 28.6 0.2 2.7e-06 27.3 0.2 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EMG50669.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 2 0 0 2 2 2 0 Peptidase C26 DASH_Dam1 PF08653.10 EMG50670.1 - 0.53 10.1 2.8 1.3 8.9 0.7 2.7 1 1 1 2 2 2 0 DASH complex subunit Dam1 Takusan PF04822.13 EMG50670.1 - 1.9 8.4 12.4 0.75 9.7 7.9 2.8 2 0 0 2 2 2 0 Takusan Myb_DNA-binding PF00249.31 EMG50671.1 - 3.5e-26 91.1 3.2 1.6e-14 53.8 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMG50671.1 - 1.2e-16 60.7 0.9 1.2e-12 47.8 0.0 3.7 3 1 1 4 4 4 2 Myb-like DNA-binding domain SLIDE PF09111.10 EMG50671.1 - 0.014 15.4 3.8 0.039 14.0 3.8 1.7 1 0 0 1 1 1 0 SLIDE DUF3043 PF11241.8 EMG50671.1 - 2.2 8.3 8.3 4.1 7.4 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) ADH_N PF08240.12 EMG50672.1 - 4e-05 23.5 0.0 0.00016 21.5 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PNGaseA PF12222.8 EMG50673.1 - 1.2e-110 370.4 1.7 6.1e-66 223.1 0.9 2.1 2 0 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Vps35 PF03635.17 EMG50674.1 - 2.8e-254 846.0 36.0 3.2e-254 845.8 36.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RPN6_C_helix PF18503.1 EMG50674.1 - 0.17 11.7 0.9 2.2 8.1 0.3 2.6 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain DUF3069 PF11269.8 EMG50674.1 - 4.9 7.4 6.8 2.9 8.2 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3069) ADH_zinc_N_2 PF13602.6 EMG50675.1 - 2.5e-17 64.2 0.0 4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMG50675.1 - 2.3e-12 47.0 0.0 8.6e-12 45.2 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase CTP_transf_3 PF02348.19 EMG50675.1 - 0.087 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase THF_DHG_CYH_C PF02882.19 EMG50675.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EMG50676.1 - 4e-19 69.1 0.1 9.2e-19 67.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG50676.1 - 5e-16 58.5 0.0 6.8e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMG50676.1 - 2.8e-12 46.4 0.0 4e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EMG50676.1 - 5.8e-11 42.6 0.2 2.1e-10 40.8 0.2 1.9 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMG50676.1 - 7.3e-08 32.2 0.2 1.2e-07 31.5 0.2 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMG50676.1 - 9.9e-07 28.5 1.9 3.1e-05 23.6 0.5 2.3 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EMG50676.1 - 5.9e-05 22.6 0.1 0.0015 18.0 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EMG50676.1 - 9.7e-05 21.6 0.2 0.00016 20.9 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EMG50676.1 - 0.00015 21.8 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 EMG50676.1 - 0.019 15.1 0.1 0.041 14.0 0.1 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF4886 PF16227.5 EMG50676.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) RmlD_sub_bind PF04321.17 EMG50676.1 - 0.024 13.7 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.6 EMG50676.1 - 0.089 12.3 0.0 0.24 10.9 0.0 1.7 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 EMG50677.1 - 2e-13 50.5 0.0 3.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG50677.1 - 1.1e-05 25.3 0.0 0.00013 21.8 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMG50677.1 - 4.6e-05 24.5 0.0 8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 EMG50677.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain tRNA_int_endo PF01974.17 EMG50678.1 - 1.2e-07 31.7 1.0 1.9e-07 31.1 1.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain FlgO PF17680.1 EMG50678.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 FlgO protein AATase PF07247.12 EMG50679.1 - 3.3e-29 101.8 8.1 4.9e-29 101.2 3.6 2.8 2 1 0 2 2 2 1 Alcohol acetyltransferase Ran_BP1 PF00638.18 EMG50680.1 - 1.5e-23 83.4 0.1 2.5e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain Herpes_UL6 PF01763.16 EMG50680.1 - 0.11 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like U1snRNP70_N PF12220.8 EMG50681.1 - 1.5e-16 60.8 7.2 1.5e-16 60.8 7.2 2.1 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EMG50681.1 - 8.3e-16 57.6 0.0 1.4e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipoprotein_7 PF01540.16 EMG50681.1 - 0.012 15.0 0.5 0.017 14.5 0.5 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein PAP1 PF08601.10 EMG50681.1 - 0.063 13.0 7.5 0.1 12.3 7.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 RRM_7 PF16367.5 EMG50681.1 - 0.098 12.8 0.2 0.37 10.9 0.0 2.0 2 1 0 2 2 2 0 RNA recognition motif Cyt-b5 PF00173.28 EMG50682.1 - 1.8e-09 37.6 0.1 2.1e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.21 EMG50683.1 - 8.1e-95 318.2 39.9 1.1e-94 317.8 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMG50683.1 - 3.7e-22 78.8 42.7 5.4e-22 78.2 42.7 1.2 1 0 0 1 1 1 1 Amino acid permease Homeodomain PF00046.29 EMG50683.1 - 0.12 12.2 0.6 3.5 7.5 0.2 2.4 2 0 0 2 2 2 0 Homeodomain Nucleos_tra2_C PF07662.13 EMG50684.1 - 7.5e-66 221.9 2.2 7.5e-66 221.9 2.2 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EMG50684.1 - 1.5e-20 73.5 2.6 1.5e-20 73.5 2.6 3.8 3 0 0 3 3 3 2 Na+ dependent nucleoside transporter N-terminus DUF2628 PF10947.8 EMG50684.1 - 0.063 13.6 0.4 0.063 13.6 0.4 4.1 5 2 1 6 6 6 0 Protein of unknown function (DUF2628) Orf78 PF06024.12 EMG50684.1 - 0.066 13.5 3.6 0.11 12.8 0.1 2.9 3 0 0 3 3 3 0 Orf78 (ac78) DUF2721 PF11026.8 EMG50684.1 - 3.2 7.7 12.1 15 5.5 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2721) ATG2_CAD PF13329.6 EMG50685.1 - 3e-51 173.2 0.0 1.7e-50 170.8 0.0 2.4 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EMG50685.1 - 1.4e-24 86.3 0.0 4.1e-24 84.7 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF4316 PF14195.6 EMG50685.1 - 1.6 8.5 6.5 0.15 11.8 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) Las1 PF04031.13 EMG50686.1 - 6.3e-49 166.0 0.3 6.9e-48 162.6 0.3 2.2 2 0 0 2 2 2 1 Las1-like Pro_3_hydrox_C PF05373.11 EMG50686.1 - 0.11 12.5 0.2 0.45 10.6 0.1 2.1 1 1 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Dynamitin PF04912.14 EMG50686.1 - 0.41 9.9 3.8 1 8.6 0.3 2.1 2 0 0 2 2 2 0 Dynamitin 4HBT_3 PF13622.6 EMG50687.1 - 4.5e-25 89.3 0.0 7.5e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMG50687.1 - 4.2e-10 39.6 4.0 9.2e-05 22.3 1.2 3.9 2 2 1 3 3 3 3 Acyl-CoA thioesterase 4HBT_3 PF13622.6 EMG50688.1 - 2.9e-31 109.6 0.0 6.9e-31 108.4 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMG50688.1 - 2.2e-12 47.0 0.7 3e-10 40.1 0.2 2.8 2 1 0 2 2 2 2 Acyl-CoA thioesterase FlaE PF07559.14 EMG50688.1 - 0.13 12.9 0.0 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 Flagellar basal body protein FlaE 4HBT_3 PF13622.6 EMG50689.1 - 4.2e-35 122.2 0.0 5.1e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMG50689.1 - 1.1e-18 67.4 1.6 1.1e-10 41.5 0.6 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.6 EMG50690.1 - 5.8e-33 115.2 0.0 7.2e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMG50690.1 - 2.8e-14 53.1 0.1 4.5e-11 42.7 0.1 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase Methyltransf_31 PF13847.6 EMG50691.1 - 7.7e-20 71.2 0.3 1.5e-19 70.3 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMG50691.1 - 1.8e-09 38.1 0.0 3.6e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG50691.1 - 1.4e-07 32.1 0.5 3.2e-07 31.0 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMG50691.1 - 1e-06 29.3 0.0 2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EMG50691.1 - 0.00011 22.3 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMG50691.1 - 0.0014 18.5 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMG50691.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF748 PF05359.11 EMG50691.1 - 0.017 15.3 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) MTS PF05175.14 EMG50691.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RVT_1 PF00078.27 EMG50692.1 - 2.2e-30 105.9 2.4 2.8e-30 105.5 0.7 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTRF_SDPR PF15237.6 EMG50692.1 - 0.0071 16.0 0.3 0.0071 16.0 0.3 1.7 2 0 0 2 2 2 1 PTRF/SDPR family Aminotran_5 PF00266.19 EMG50693.1 - 3.3e-42 144.8 0.0 3.9e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DHHA2 PF02833.14 EMG50694.1 - 5.1e-28 98.1 0.6 1.6e-27 96.4 0.3 1.9 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 EMG50694.1 - 2.5e-09 37.3 0.1 4.1e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 DHH family DUF1959 PF09218.10 EMG50694.1 - 0.0015 18.6 0.3 1.3 9.2 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1959) PMT PF02366.18 EMG50695.1 - 2.7e-82 276.0 22.8 2.7e-82 276.0 22.8 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EMG50695.1 - 1.1e-60 204.7 8.9 1.1e-60 204.7 8.9 3.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EMG50695.1 - 1.7e-17 63.9 1.2 1.7e-17 63.9 1.2 1.8 2 0 0 2 2 2 1 MIR domain CCSMST1 PF15013.6 EMG50695.1 - 0.036 14.2 0.1 8.5 6.6 0.0 3.3 3 0 0 3 3 3 0 CCSMST1 family Hamartin PF04388.12 EMG50696.1 - 5e-13 48.6 6.4 5e-13 48.6 6.4 2.5 1 1 0 2 2 2 1 Hamartin protein NUDIX PF00293.28 EMG50697.1 - 4e-09 36.6 0.0 7.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EMG50697.1 - 1.3e-08 34.8 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) AMP-binding PF00501.28 EMG50698.1 - 1.7e-69 234.5 0.0 2.2e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Mre11_DNA_bind PF04152.14 EMG50698.1 - 0.1 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain GTP_EFTU PF00009.27 EMG50700.1 - 3.6e-49 166.9 0.0 6.6e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EMG50700.1 - 1.4e-39 134.5 3.6 3.2e-39 133.4 3.6 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EMG50700.1 - 4.5e-22 77.9 0.0 1e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMG50700.1 - 2.9e-07 30.8 0.3 2.3e-06 27.9 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMG50700.1 - 4.7e-05 23.4 0.0 0.00013 22.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EMG50700.1 - 0.00058 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 EMG50700.1 - 0.0028 17.7 0.0 0.0072 16.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 EMG50700.1 - 0.0073 15.8 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 EMG50700.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain MMR_HSR1_Xtn PF16897.5 EMG50700.1 - 0.062 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PALP PF00291.25 EMG50701.1 - 4.7e-77 259.3 0.0 6.6e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EMG50701.1 - 2.1e-18 65.9 0.0 3.9e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal regulatory domain of Threonine dehydratase N_BRCA1_IG PF16158.5 EMG50701.1 - 0.11 13.2 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Ig-like domain from next to BRCA1 gene NIR_SIR PF01077.22 EMG50703.1 - 2.8e-51 173.2 0.0 1.9e-47 160.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EMG50703.1 - 5.5e-30 103.0 0.1 1.7e-14 53.4 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EMG50703.1 - 2.4e-28 99.1 0.1 6.8e-28 97.7 0.1 1.9 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EMG50703.1 - 4.1e-07 30.0 0.0 5.9e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg VWA_2 PF13519.6 EMG50704.1 - 2.4e-23 82.8 0.7 2.4e-22 79.6 0.0 2.4 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 EMG50704.1 - 1.5e-08 35.1 1.7 2.4e-08 34.5 1.7 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EMG50704.1 - 3e-05 23.9 0.0 4.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 EMG50704.1 - 0.0072 16.2 0.5 0.021 14.7 0.5 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF4362 PF14275.6 EMG50704.1 - 0.02 15.2 0.2 4.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4362) PDH PF02153.17 EMG50704.1 - 0.026 13.5 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase Prp18 PF02840.15 EMG50704.1 - 0.082 13.0 0.2 0.082 13.0 0.2 1.8 2 0 0 2 2 2 0 Prp18 domain GAF PF01590.26 EMG50705.1 - 4.8e-05 24.0 0.0 8.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 GAF domain Swi3 PF07962.12 EMG50706.1 - 7.4e-30 102.8 0.1 1.1e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 HMW1C_N PF18071.1 EMG50706.1 - 0.075 12.8 0.3 0.22 11.3 0.0 1.9 2 1 1 3 3 3 0 HMW1C N-terminal HECT_2 PF09814.9 EMG50707.1 - 5.1e-33 114.5 0.1 6.1e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding LPD15 PF18828.1 EMG50707.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 Hyphal_reg_CWP PF11765.8 EMG50709.1 - 3.5e-54 184.0 15.0 5.3e-54 183.4 15.0 1.2 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hus1 PF04005.12 EMG50710.1 - 9.9e-73 244.8 1.1 1.1e-72 244.6 1.1 1.0 1 0 0 1 1 1 1 Hus1-like protein CPSF73-100_C PF11718.8 EMG50711.1 - 5.9e-68 228.7 1.6 1e-67 227.8 1.6 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EMG50711.1 - 1.1e-29 102.9 0.0 2.9e-29 101.6 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EMG50711.1 - 7.4e-21 74.5 0.0 2.2e-20 72.9 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EMG50711.1 - 6.1e-20 72.1 0.4 1.7e-19 70.6 0.4 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EMG50711.1 - 1.5e-14 53.7 0.0 3.7e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EMG50711.1 - 1.5e-06 27.8 0.0 6.5e-06 25.8 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMG50711.1 - 1.1e-05 25.4 0.0 9.1e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EMG50711.1 - 0.00058 19.1 0.0 0.0013 18.0 0.0 1.6 1 0 0 1 1 1 1 Putative beta-lactamase-like family DWNN PF08783.11 EMG50711.1 - 0.1 12.9 0.0 2.7 8.4 0.0 2.7 2 0 0 2 2 2 0 DWNN domain DNA_pol_phi PF04931.13 EMG50711.1 - 0.2 9.8 8.0 0.3 9.1 8.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 EMG50711.1 - 5.6 6.0 9.2 9.3 5.3 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RTA1 PF04479.13 EMG50712.1 - 7.9e-75 251.0 7.5 7.9e-75 251.0 7.5 2.3 1 1 2 3 3 3 2 RTA1 like protein RTA1 PF04479.13 EMG50713.1 - 1.1e-68 231.0 12.8 1.1e-68 231.0 12.8 1.6 2 0 0 2 2 2 1 RTA1 like protein DUF3784 PF12650.7 EMG50713.1 - 0.019 15.1 0.3 0.019 15.1 0.3 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF3784) S-antigen PF05756.11 EMG50713.1 - 0.15 12.5 1.1 0.38 11.1 1.1 1.7 1 0 0 1 1 1 0 S-antigen protein Glyoxalase PF00903.25 EMG50714.1 - 4.3e-09 36.6 0.0 1.8e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMG50714.1 - 1.7e-05 25.0 0.0 2.3e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EMG50714.1 - 0.011 15.7 0.3 4.8 7.1 0.1 2.8 2 1 0 2 2 2 0 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EMG50714.1 - 0.022 14.9 0.0 0.12 12.5 0.0 1.8 1 1 0 2 2 2 0 Glyoxalase-like domain ADIP PF11559.8 EMG50715.1 - 2.2e-29 102.5 21.9 2.7e-29 102.2 21.9 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 EMG50715.1 - 0.00035 20.7 10.9 0.00057 20.0 10.9 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 EMG50715.1 - 0.0064 16.0 13.5 0.009 15.5 13.5 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 FlxA PF14282.6 EMG50715.1 - 0.024 14.6 18.8 0.041 13.9 3.2 3.0 2 1 1 3 3 3 0 FlxA-like protein Nup54 PF13874.6 EMG50715.1 - 0.026 14.6 11.2 0.84 9.7 0.3 2.7 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Csm1_N PF18504.1 EMG50715.1 - 0.034 14.5 3.6 0.034 14.5 3.6 3.5 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF3375 PF11855.8 EMG50715.1 - 0.041 12.8 1.0 0.056 12.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) CENP-F_leu_zip PF10473.9 EMG50715.1 - 0.049 13.7 9.5 0.11 12.6 9.5 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CSN4_RPN5_eIF3a PF18420.1 EMG50715.1 - 0.066 13.4 0.1 0.3 11.3 0.1 2.3 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain SlyX PF04102.12 EMG50715.1 - 0.074 13.7 6.2 0.1 13.2 0.6 3.2 2 1 1 3 3 2 0 SlyX ARTD15_N PF18084.1 EMG50715.1 - 0.097 12.9 1.2 0.61 10.4 0.1 2.6 2 1 0 2 2 2 0 ARTD15 N-terminal domain IFT20 PF14931.6 EMG50715.1 - 0.1 12.8 17.3 0.8 9.9 7.6 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF2802 PF10975.8 EMG50715.1 - 0.23 11.6 2.6 14 5.9 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) APG6_N PF17675.1 EMG50715.1 - 0.25 11.9 8.3 0.44 11.1 8.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region LPP PF04728.13 EMG50715.1 - 0.29 11.6 7.4 4.4 7.8 0.3 3.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Atg14 PF10186.9 EMG50715.1 - 0.54 9.3 12.5 0.83 8.7 12.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2779 PF11074.8 EMG50715.1 - 0.59 10.6 5.1 1.4 9.4 5.1 1.7 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) DUF2524 PF10732.9 EMG50715.1 - 0.73 10.2 6.5 7 7.0 5.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) DUF641 PF04859.12 EMG50715.1 - 0.75 10.1 14.2 3.7 7.9 1.0 2.3 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF948 PF06103.11 EMG50715.1 - 0.88 9.9 10.0 1.2 9.5 6.5 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 EMG50715.1 - 1.2 8.0 6.8 1.3 7.9 6.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ZapB PF06005.12 EMG50715.1 - 1.5 9.3 12.3 8.3 6.9 2.5 2.7 1 1 1 2 2 2 0 Cell division protein ZapB Phage_GPO PF05929.11 EMG50715.1 - 1.8 8.1 8.7 7.3 6.1 8.7 1.8 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 EMG50715.1 - 2 7.7 8.2 3.7 6.8 8.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Remorin_C PF03763.13 EMG50715.1 - 2.4 8.1 12.0 0.16 11.9 4.5 2.2 1 1 1 2 2 2 0 Remorin, C-terminal region DUF724 PF05266.14 EMG50715.1 - 2.5 7.9 13.8 0.64 9.8 9.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 EMG50715.1 - 6.4 6.8 12.8 5.4 7.1 9.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 EMG50715.1 - 6.7 7.1 10.4 26 5.2 10.4 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region FAM76 PF16046.5 EMG50715.1 - 8.8 5.6 14.5 28 4.0 14.5 1.8 1 1 0 1 1 1 0 FAM76 protein RF-1 PF00472.20 EMG50716.1 - 8e-22 77.4 6.2 2.8e-21 75.6 6.1 1.9 1 1 0 1 1 1 1 RF-1 domain Pinin_SDK_memA PF04696.13 EMG50716.1 - 0.21 11.6 12.2 0.54 10.3 12.2 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region MCM PF00493.23 EMG50717.1 - 2.5e-104 347.3 0.0 4.5e-104 346.4 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMG50717.1 - 1.5e-37 128.3 1.1 2.6e-37 127.5 1.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EMG50717.1 - 3.1e-27 94.8 3.5 9.8e-27 93.2 3.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMG50717.1 - 2.6e-16 60.1 1.8 6.5e-16 58.8 1.8 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMG50717.1 - 1.3e-06 28.0 0.0 0.00077 18.9 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMG50717.1 - 2.1e-05 24.6 0.0 5.7e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EMG50717.1 - 0.00016 21.5 0.1 0.0015 18.4 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 EMG50717.1 - 0.026 14.7 0.2 0.18 12.0 0.2 2.3 2 0 0 2 2 2 0 Midasin AAA lid domain Sigma54_activat PF00158.26 EMG50717.1 - 0.07 12.8 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 EMG50717.1 - 0.13 12.7 0.0 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KilA-N PF04383.13 EMG50719.1 - 0.00055 19.8 0.1 0.00055 19.8 0.1 3.7 3 2 0 3 3 3 1 KilA-N domain Glyoxalase PF00903.25 EMG50720.1 - 2.2e-08 34.3 0.1 8e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMG50720.1 - 4e-06 27.1 0.0 0.0024 18.1 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EMG50720.1 - 0.071 13.2 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain RTA1 PF04479.13 EMG50721.1 - 1e-68 231.0 13.7 1.6e-68 230.4 13.7 1.3 1 0 0 1 1 1 1 RTA1 like protein Pox_D5 PF03288.16 EMG50721.1 - 0.13 12.8 0.3 0.25 11.9 0.3 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like Wzy_C_2 PF11846.8 EMG50721.1 - 0.38 10.7 0.0 0.38 10.7 0.0 2.3 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal RTA1 PF04479.13 EMG50722.1 - 2.3e-69 233.1 15.5 2.3e-69 233.1 15.5 1.5 2 0 0 2 2 2 1 RTA1 like protein FWWh PF14922.6 EMG50722.1 - 0.82 9.6 5.7 0.095 12.6 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function RRM_1 PF00076.22 EMG50723.1 - 5.9e-09 35.6 3.0 0.012 15.4 0.1 4.5 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.9 EMG50723.1 - 1.7e-08 34.0 18.3 1.7e-08 34.0 18.3 4.9 3 1 1 4 4 4 1 Putative RRM domain Aa_trans PF01490.18 EMG50724.1 - 1.7e-53 181.8 31.5 2.2e-53 181.5 31.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein B56 PF01603.20 EMG50725.1 - 4.1e-176 586.0 16.3 3.4e-165 550.0 11.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EMG50725.1 - 0.6 10.0 3.6 6.3 6.7 0.4 2.5 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Ndc1_Nup PF09531.10 EMG50725.1 - 0.63 8.7 11.2 1.1 7.9 11.2 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IMPDH PF00478.25 EMG50726.1 - 3e-136 454.0 3.5 3.4e-136 453.8 3.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EMG50726.1 - 7.1e-11 42.4 0.2 0.00053 20.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EMG50726.1 - 8e-09 35.0 0.4 2.8e-08 33.2 0.4 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 EMG50726.1 - 5.1e-07 29.4 5.0 0.00074 19.0 4.4 2.6 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 EMG50726.1 - 4e-05 23.2 1.2 0.00095 18.7 1.2 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EMG50726.1 - 0.0017 17.7 1.8 0.0039 16.5 0.4 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 EMG50726.1 - 0.01 15.2 0.1 0.033 13.6 0.1 1.8 1 0 0 1 1 1 0 KDPG and KHG aldolase YpsA PF06908.11 EMG50726.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Ribosomal_L28e PF01778.17 EMG50727.1 - 6.9e-39 133.2 4.0 6.9e-39 133.2 4.0 2.2 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 EMG50727.1 - 6.2e-31 107.0 23.0 6.2e-31 107.0 23.0 2.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region CH PF00307.31 EMG50727.1 - 2.2e-09 37.5 0.3 8.8e-09 35.5 0.1 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain BUD22 PF09073.10 EMG50727.1 - 0.00022 20.7 25.0 0.0003 20.3 25.0 1.1 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 EMG50727.1 - 0.004 15.8 27.0 0.0059 15.3 27.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PYC_OADA PF02436.18 EMG50727.1 - 0.34 10.6 8.7 0.27 10.9 7.0 1.8 2 0 0 2 2 2 0 Conserved carboxylase domain DUF4820 PF16091.5 EMG50727.1 - 0.34 10.2 15.8 0.018 14.4 9.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) ATP_sub_h PF10775.9 EMG50728.1 - 1.1e-20 73.4 0.6 1.5e-20 72.9 0.6 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h RE_MamI PF09567.10 EMG50728.1 - 0.1 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 MamI restriction endonuclease zf-U1 PF06220.12 EMG50729.1 - 4.8e-18 64.6 10.9 1.1e-17 63.5 10.9 1.6 1 1 0 1 1 1 1 U1 zinc finger POM121 PF15229.6 EMG50729.1 - 0.14 11.8 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 POM121 family Ras PF00071.22 EMG50730.1 - 5e-49 166.0 0.0 6.2e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG50730.1 - 2.8e-29 101.8 0.0 7.4e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG50730.1 - 1.8e-10 40.5 0.0 2.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 EMG50730.1 - 0.00046 20.5 0.1 0.0022 18.4 0.1 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 EMG50730.1 - 0.0008 19.5 0.0 0.0016 18.5 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EMG50730.1 - 0.00093 18.6 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EMG50730.1 - 0.02 14.8 0.1 5.8 6.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 EMG50730.1 - 0.021 14.3 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 EMG50730.1 - 0.03 13.5 2.2 1.6 7.8 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 EMG50730.1 - 0.038 13.5 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EMG50730.1 - 0.048 13.4 0.2 0.061 13.0 0.2 1.4 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EMG50730.1 - 0.085 12.9 0.1 0.19 11.7 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EMG50730.1 - 0.1 12.7 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EMG50730.1 - 0.1 11.9 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 EMG50730.1 - 0.15 12.4 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EMG50730.1 - 0.16 11.3 0.4 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Septin Pkinase PF00069.25 EMG50732.1 - 3.7e-35 121.6 4.6 2.4e-20 73.0 0.0 4.2 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50732.1 - 4.9e-12 45.7 0.1 0.0026 17.1 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 EMG50732.1 - 0.0068 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Epimerase PF01370.21 EMG50733.1 - 5.7e-16 58.7 0.0 7.5e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG50733.1 - 7.3e-15 54.7 0.0 9.9e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMG50733.1 - 6e-08 32.2 0.0 7.5e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EMG50733.1 - 1.2e-06 28.2 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EMG50733.1 - 1.3e-06 28.4 0.1 4.4e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EMG50733.1 - 3.3e-06 26.7 0.1 4.5e-06 26.3 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMG50733.1 - 8.8e-06 25.1 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EMG50733.1 - 0.00012 22.0 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMG50733.1 - 0.0012 18.5 0.0 0.002 17.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 EMG50733.1 - 0.0053 17.3 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 EMG50733.1 - 0.032 13.3 0.0 0.18 10.9 0.0 2.0 2 1 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 EMG50733.1 - 0.04 13.5 0.3 0.085 12.4 0.2 1.8 2 1 0 2 2 2 0 NmrA-like family Mpv17_PMP22 PF04117.12 EMG50734.1 - 1.4e-19 70.0 4.1 2.9e-19 69.0 4.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 EMG50735.1 - 2.1e-23 82.3 3.6 2.1e-23 82.3 3.6 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family OGG_N PF07934.12 EMG50736.1 - 1.2 9.3 4.4 0.89 9.7 0.8 2.4 2 0 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain CDT1_C PF16679.5 EMG50738.1 - 6.1e-10 39.4 0.1 1.2e-09 38.4 0.1 1.5 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain E1-E2_ATPase PF00122.20 EMG50739.1 - 8.4e-21 74.3 0.0 1.7e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EMG50739.1 - 5e-17 62.9 0.0 2.6e-09 37.7 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMG50739.1 - 1.1e-05 25.4 0.0 7.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EMG50739.1 - 5.8e-05 23.0 0.4 0.00014 21.7 0.4 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EMG50739.1 - 0.064 12.8 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Sugar_tr PF00083.24 EMG50740.1 - 1.3e-55 189.1 28.1 4.7e-55 187.2 28.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG50740.1 - 6.9e-20 71.3 54.2 5.6e-14 51.8 34.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DMT_YdcZ PF04657.13 EMG50740.1 - 0.0063 16.8 2.1 0.0063 16.8 2.1 3.7 2 1 1 3 3 3 2 Putative inner membrane exporter, YdcZ Pkinase PF00069.25 EMG50741.1 - 5.8e-57 193.0 0.0 5.6e-56 189.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50741.1 - 1.8e-27 96.3 0.0 4.4e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EMG50741.1 - 2.7e-07 31.2 1.1 1.1e-06 29.3 1.1 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EMG50741.1 - 0.0004 19.8 0.0 0.024 14.0 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EMG50741.1 - 0.00053 19.4 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMG50741.1 - 0.018 15.0 0.0 0.09 12.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family TRPM_tetra PF16519.5 EMG50741.1 - 0.08 13.1 0.4 0.08 13.1 0.4 2.4 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Mif2_N PF15624.6 EMG50741.1 - 0.1 13.3 8.1 0.22 12.3 8.1 1.6 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Nop PF01798.18 EMG50742.1 - 3.7e-58 196.7 3.9 3.7e-58 196.7 3.9 2.2 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EMG50742.1 - 4e-32 111.7 7.9 9e-32 110.5 7.9 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain tRNA-synt_1 PF00133.22 EMG50743.1 - 1.9e-229 762.9 0.6 1.9e-229 762.9 0.6 2.8 3 1 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMG50743.1 - 4.3e-35 120.9 0.1 4.3e-35 120.9 0.1 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EMG50743.1 - 1.2e-16 60.4 0.2 1.4e-08 33.9 0.1 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EMG50743.1 - 9.8e-09 35.0 12.0 9.8e-07 28.5 0.0 3.6 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EMG50743.1 - 0.0049 16.3 0.1 0.24 10.7 0.1 2.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 EMG50743.1 - 0.44 9.8 0.0 0.44 9.8 0.0 3.7 4 0 0 4 4 4 0 tRNA synthetases class I (W and Y) NARP1 PF12569.8 EMG50743.1 - 3.1 6.6 13.9 6.9 5.5 13.9 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 tRNA-synt_1c PF00749.21 EMG50743.1 - 4.5 6.1 12.0 2.5 6.9 0.0 3.8 4 0 0 4 4 4 0 tRNA synthetases class I (E and Q), catalytic domain tRNA_m1G_MT PF01746.21 EMG50745.1 - 2.5e-24 86.1 0.1 2.5e-24 86.1 0.1 1.7 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase CAF1 PF04857.20 EMG50745.1 - 0.049 12.8 1.5 0.054 12.7 1.5 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease Rad4 PF03835.15 EMG50746.1 - 1.2e-08 34.7 0.8 2.5e-08 33.7 0.8 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EMG50746.1 - 0.00019 21.9 0.5 0.00062 20.2 0.5 1.9 1 1 0 1 1 1 1 Transglutaminase-like superfamily Desulfoferrod_N PF06397.12 EMG50746.1 - 0.03 13.9 0.5 0.072 12.7 0.5 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Nrap_D6 PF17407.2 EMG50746.1 - 0.12 12.5 0.6 0.86 9.8 0.1 2.2 2 0 0 2 2 2 0 Nrap protein domain 6 CPL PF08144.11 EMG50747.1 - 2.5e-37 128.4 1.0 2.5e-37 128.4 1.0 4.0 4 1 1 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 EMG50747.1 - 0.00015 21.2 2.0 7 6.6 0.0 5.6 6 0 0 6 6 6 2 Pumilio-family RNA binding repeat SAC3 PF12209.8 EMG50747.1 - 0.041 14.1 0.9 2 8.6 0.1 3.7 3 0 0 3 3 3 0 Leucine permease transcriptional regulator helical domain CDC45 PF02724.14 EMG50747.1 - 0.072 11.4 13.8 0.12 10.7 13.8 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 EMG50747.1 - 0.38 9.9 11.7 1.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 EMG50747.1 - 0.9 7.7 23.7 1.7 6.8 23.7 1.4 1 0 0 1 1 1 0 Nop14-like family Pex2_Pex12 PF04757.14 EMG50748.1 - 3.9e-41 141.1 9.7 4.8e-41 140.8 9.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 EMG50748.1 - 3e-05 23.9 4.3 6e-05 22.9 4.3 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EMG50748.1 - 0.0003 20.6 4.7 0.00051 19.9 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG50748.1 - 0.00057 19.9 3.8 0.0011 18.9 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EMG50748.1 - 0.00079 19.5 2.7 0.0019 18.3 2.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EMG50748.1 - 0.0022 17.8 1.5 0.017 15.0 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMG50748.1 - 0.0052 16.6 2.9 0.12 12.3 1.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMG50748.1 - 0.27 11.6 6.1 1 9.7 6.1 1.9 1 1 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 EMG50748.1 - 4.1 7.3 6.0 21 5.0 6.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 EMG50749.1 - 1.4e-68 231.1 0.1 6.2e-68 229.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50749.1 - 6.1e-50 169.9 0.1 2.3e-49 168.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMG50749.1 - 6.2e-06 25.2 0.0 1.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EMG50749.1 - 0.002 17.5 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EMG50749.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EMG50749.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMG50749.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Epimerase PF01370.21 EMG50750.1 - 1.2e-16 61.0 0.1 1.5e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMG50750.1 - 1.3e-15 57.2 0.0 1.8e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMG50750.1 - 1.2e-07 31.8 0.1 3e-07 30.5 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EMG50750.1 - 4.2e-07 29.6 0.0 6.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EMG50750.1 - 8.5e-07 28.4 0.3 6.4e-06 25.5 0.3 1.9 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EMG50750.1 - 2.1e-06 27.4 0.1 3.6e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMG50750.1 - 1.1e-05 24.8 0.2 2.1e-05 23.8 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EMG50750.1 - 0.00015 21.7 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMG50750.1 - 0.00061 19.4 0.1 0.0011 18.6 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 EMG50750.1 - 0.0022 18.5 0.0 0.006 17.1 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Zeta_toxin PF06414.12 EMG50750.1 - 0.0044 16.3 0.0 0.0077 15.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NmrA PF05368.13 EMG50750.1 - 0.005 16.4 0.5 0.029 13.9 0.2 2.2 2 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EMG50750.1 - 0.0054 15.9 0.0 0.1 11.7 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain ADH_zinc_N PF00107.26 EMG50751.1 - 4e-24 85.1 0.0 6.8e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMG50751.1 - 1.4e-17 63.6 0.0 2.3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EMG50751.1 - 0.0012 19.9 0.0 0.0024 18.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Nucleoporin_N PF08801.11 EMG50752.1 - 2.5e-56 191.3 3.7 4.5e-56 190.4 3.7 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Brix PF04427.18 EMG50752.1 - 3.5e-39 134.9 1.8 1.1e-38 133.3 1.8 1.9 1 0 0 1 1 1 1 Brix domain Nucleoporin_C PF03177.14 EMG50752.1 - 1.3e-25 90.2 12.0 9.3e-25 87.4 10.2 2.4 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal PBP1_TM PF14812.6 EMG50752.1 - 4.1 7.8 6.9 13 6.2 6.9 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DASH_Dad2 PF08654.10 EMG50753.1 - 7.9e-22 77.5 4.2 1.8e-21 76.4 4.2 1.7 1 1 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 EMG50753.1 - 8e-05 22.3 0.5 0.00014 21.6 0.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 Baculo_PEP_C PF04513.12 EMG50753.1 - 0.00059 19.9 1.2 0.0007 19.6 1.2 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus P_gingi_FimA PF06321.11 EMG50753.1 - 0.018 15.1 0.9 0.036 14.2 0.9 1.6 1 1 0 1 1 1 0 Major fimbrial subunit protein (FimA) NPV_P10 PF05531.12 EMG50753.1 - 0.036 14.5 1.4 0.036 14.5 1.4 1.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DASH_Dad4 PF08650.10 EMG50754.1 - 0.013 15.4 6.8 0.034 14.1 6.8 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad4 FlaC_arch PF05377.11 EMG50754.1 - 0.02 15.3 2.5 0.02 15.3 2.5 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2096 PF09869.9 EMG50754.1 - 0.031 14.4 0.3 0.065 13.3 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Glu-tRNAGln PF02686.15 EMG50754.1 - 0.034 14.5 1.3 0.11 12.8 0.0 2.1 1 1 1 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DLP_helical PF18709.1 EMG50754.1 - 0.04 13.1 2.3 0.072 12.3 2.3 1.5 1 0 0 1 1 1 0 Dynamin-like helical domain FliJ PF02050.16 EMG50754.1 - 0.045 14.0 4.7 0.077 13.2 1.4 2.5 2 1 0 3 3 3 0 Flagellar FliJ protein Herpes_UL6 PF01763.16 EMG50754.1 - 0.073 11.6 4.7 0.12 10.9 4.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF489 PF04356.12 EMG50754.1 - 0.2 11.6 4.9 0.087 12.8 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF489) DUF3573 PF12097.8 EMG50754.1 - 0.21 10.4 5.9 0.33 9.7 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Shugoshin_C PF07557.11 EMG50754.1 - 0.25 11.2 12.3 0.14 12.0 8.2 2.5 2 0 0 2 2 2 0 Shugoshin C terminus ATG16 PF08614.11 EMG50754.1 - 1.2 9.3 16.7 0.13 12.4 6.2 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF848 PF05852.11 EMG50754.1 - 1.8 8.7 6.0 0.29 11.3 1.5 2.0 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4407 PF14362.6 EMG50754.1 - 1.9 7.8 5.2 0.3 10.4 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 EMG50754.1 - 2.3 8.4 10.3 6.5 6.9 10.1 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 EMG50754.1 - 2.6 8.4 9.2 22 5.5 4.5 3.2 2 2 0 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EMG50754.1 - 3 7.3 9.4 0.12 11.9 2.3 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit BST2 PF16716.5 EMG50754.1 - 4.5 7.9 8.7 0.32 11.6 1.0 2.7 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 Thymidylat_synt PF00303.19 EMG50755.1 - 8.4e-114 379.2 0.0 9.5e-114 379.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HSP9_HSP12 PF04119.12 EMG50756.1 - 6.2e-23 81.0 6.4 6.9e-23 80.8 6.4 1.0 1 0 0 1 1 1 1 Heat shock protein 9/12 mCpol PF18182.1 EMG50756.1 - 0.037 14.3 0.1 0.043 14.2 0.1 1.0 1 0 0 1 1 1 0 minimal CRISPR polymerase domain KinB_sensor PF16767.5 EMG50756.1 - 0.042 14.3 0.0 0.05 14.1 0.0 1.0 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB 4HBT PF03061.22 EMG50757.1 - 2.3e-06 27.8 0.0 3.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF3918 PF13056.6 EMG50757.1 - 0.25 11.0 0.0 0.45 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Peroxin-22 PF12827.7 EMG50758.1 - 2.2e-29 101.6 0.7 3.3e-29 101.1 0.7 1.3 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family FBA_2 PF07735.17 EMG50758.1 - 0.3 11.3 8.5 2.6 8.2 1.3 2.6 2 0 0 2 2 2 0 F-box associated Gpr1_Fun34_YaaH PF01184.19 EMG50759.1 - 3.4e-92 307.7 19.3 3.9e-92 307.5 19.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3784 PF12650.7 EMG50759.1 - 0.94 9.7 15.3 0.17 12.1 4.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) S_4TM PF18159.1 EMG50759.1 - 1.4 8.1 4.3 2.5 7.3 4.3 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Sugar_tr PF00083.24 EMG50760.1 - 9.9e-149 496.0 34.3 1.1e-148 495.8 34.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG50760.1 - 1.4e-29 103.1 32.7 2.4e-27 95.8 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Bmt2 PF11968.8 EMG50761.1 - 9.7e-92 306.8 0.0 1.1e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EMG50761.1 - 0.0008 19.3 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DEAD PF00270.29 EMG50762.1 - 7e-40 136.6 0.0 1.9e-39 135.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG50762.1 - 7.9e-29 100.2 0.2 5.9e-28 97.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Mig-14 PF07395.11 EMG50762.1 - 0.039 13.3 1.2 0.074 12.4 0.1 2.0 3 0 0 3 3 3 0 Mig-14 AAA_22 PF13401.6 EMG50762.1 - 0.065 13.5 2.2 0.17 12.2 0.9 2.5 2 1 0 2 2 2 0 AAA domain eRF1_2 PF03464.15 EMG50763.1 - 1.4e-47 161.4 0.1 2.4e-47 160.6 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EMG50763.1 - 9.7e-37 125.9 0.1 2.2e-36 124.7 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EMG50763.1 - 5.1e-20 71.8 0.0 8.9e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EMG50763.1 - 9.8e-11 42.1 0.0 1.5e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EMG50763.1 - 1.5e-09 38.3 0.1 2.2e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Tnp_DNA_bind PF14706.6 EMG50763.1 - 0.048 13.5 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Transposase DNA-binding PTSIIB_sorb PF03830.15 EMG50763.1 - 0.18 12.0 0.5 0.77 10.0 0.1 2.1 2 0 0 2 2 2 0 PTS system sorbose subfamily IIB component CDC50 PF03381.15 EMG50764.1 - 2.8e-86 289.5 0.6 4e-86 289.0 0.6 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ADH_N_2 PF16884.5 EMG50765.1 - 3.9e-23 81.4 0.0 7.1e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EMG50765.1 - 1.9e-22 79.6 0.0 3.4e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMG50765.1 - 1.4e-05 26.1 0.0 3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LPD11 PF18824.1 EMG50765.1 - 0.00071 19.6 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 11 PLA2_B PF01735.18 EMG50767.1 - 3.5e-180 599.6 16.6 6.2e-91 305.2 6.4 2.0 1 1 1 2 2 2 2 Lysophospholipase catalytic domain IBR PF01485.21 EMG50767.1 - 0.0083 16.3 2.5 0.017 15.4 2.5 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain ParBc PF02195.18 EMG50768.1 - 1.7e-13 50.6 0.0 2e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain NAD_binding_6 PF08030.12 EMG50769.1 - 4.9e-25 88.5 0.1 1.4e-24 87.0 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMG50769.1 - 1.4e-22 79.8 0.1 2.5e-22 79.0 0.1 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EMG50769.1 - 2.3e-17 63.3 16.8 2.3e-17 63.3 16.8 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EMG50769.1 - 0.00021 21.9 0.0 0.0008 20.0 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Sugar_tr PF00083.24 EMG50771.1 - 3e-113 379.1 31.5 4e-113 378.7 31.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG50771.1 - 2.3e-29 102.4 40.7 4.8e-29 101.4 30.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EMG50772.1 - 2.1e-66 224.0 0.0 3e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50772.1 - 4.4e-31 108.1 0.0 8.3e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EMG50772.1 - 0.0016 17.8 0.1 0.0034 16.8 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMG50772.1 - 0.011 15.0 0.0 0.028 13.7 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EMG50772.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L27A PF00828.19 EMG50773.1 - 7.4e-30 104.3 0.4 2.5e-29 102.5 0.1 1.9 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 EMG50774.1 - 3.3e-58 197.1 0.0 3.9e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50774.1 - 1.4e-15 57.3 0.0 3.2e-15 56.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EMG50774.1 - 1.5e-06 28.3 0.0 1.1e-05 25.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMG50774.1 - 0.0064 16.1 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EMG50774.1 - 0.026 13.6 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EMG50774.1 - 0.062 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EMG50774.1 - 0.15 11.4 0.1 0.35 10.1 0.0 1.7 3 0 0 3 3 3 0 Kinase-like CH PF00307.31 EMG50775.1 - 9.1e-18 64.4 4.6 7.9e-14 51.8 0.3 3.7 3 0 0 3 3 3 3 Calponin homology (CH) domain Baculo_PEP_C PF04513.12 EMG50775.1 - 5.1 7.1 8.5 0.3 11.1 1.0 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2340 PF10209.9 EMG50776.1 - 2.7e-52 176.3 0.6 3e-52 176.1 0.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Cytochrom_C1 PF02167.15 EMG50777.1 - 1.2e-95 319.4 0.0 1.5e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EMG50777.1 - 0.0031 17.8 0.0 0.0072 16.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EMG50777.1 - 0.059 14.5 0.1 0.13 13.4 0.1 1.7 1 1 0 1 1 1 0 Cytochrome c Ras PF00071.22 EMG50778.1 - 3.2e-58 195.9 0.0 3.8e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMG50778.1 - 2.9e-22 79.2 0.0 4e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMG50778.1 - 7.8e-09 35.2 0.0 1.3e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMG50778.1 - 0.0011 18.5 0.0 0.008 15.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EMG50778.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EMG50778.1 - 0.0074 16.4 0.0 0.018 15.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EMG50778.1 - 0.031 14.8 0.0 0.043 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.20 EMG50778.1 - 0.035 13.3 0.0 0.077 12.1 0.0 1.4 1 1 1 2 2 2 0 G-protein alpha subunit Gtr1_RagA PF04670.12 EMG50778.1 - 0.045 13.1 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EMG50778.1 - 0.051 14.0 0.0 0.061 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EMG50778.1 - 0.1 12.5 0.0 12 5.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF3128 PF11326.8 EMG50779.1 - 5.3e-25 87.6 1.2 6.7e-25 87.3 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) Macoilin PF09726.9 EMG50781.1 - 2 6.8 5.4 2.6 6.5 5.4 1.0 1 0 0 1 1 1 0 Macoilin family FAD_binding_8 PF08022.12 EMG50782.1 - 9.8e-24 83.5 0.0 2e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EMG50782.1 - 2.2e-22 79.9 0.0 3.4e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EMG50782.1 - 6.4e-21 74.8 10.3 6.4e-21 74.8 10.3 2.4 2 1 1 3 3 3 1 Ferric reductase like transmembrane component Ysc84 PF04366.12 EMG50783.1 - 1.2e-07 31.6 0.4 1.9e-07 30.8 0.4 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Rrp44_CSD1 PF17216.3 EMG50783.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Rrp44-like cold shock domain zf-C2H2 PF00096.26 EMG50784.1 - 8.7e-33 111.0 65.9 2.8e-06 27.5 2.1 9.4 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMG50784.1 - 2.3e-27 93.3 62.5 0.00032 21.3 1.7 9.3 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMG50784.1 - 7.4e-15 54.6 64.5 4.4e-06 26.9 0.9 10.2 9 1 1 10 10 10 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EMG50784.1 - 1.4e-10 41.1 29.5 0.46 10.8 0.0 8.6 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMG50784.1 - 1.2e-08 35.1 21.6 0.18 12.3 0.8 7.2 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 EMG50784.1 - 0.029 14.6 24.1 6 7.2 1.4 5.0 2 1 2 5 5 5 0 C2H2-type zinc ribbon zf-FCS PF06467.14 EMG50784.1 - 0.042 13.8 0.7 0.042 13.8 0.7 4.9 5 1 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf_UBZ PF18439.1 EMG50784.1 - 0.19 11.3 0.1 0.19 11.3 0.1 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_aberr PF17017.5 EMG50784.1 - 0.21 11.7 30.4 0.6 10.2 2.7 5.1 2 1 2 5 5 5 0 Aberrant zinc-finger IBR PF01485.21 EMG50784.1 - 0.86 9.9 35.2 0.048 13.9 4.3 5.4 2 1 3 5 5 5 0 IBR domain, a half RING-finger domain zf_ZIC PF18366.1 EMG50784.1 - 2.7 8.2 14.2 2.5 8.3 0.0 4.7 5 0 0 5 5 5 0 Zic proteins zinc finger domain zinc_ribbon_4 PF13717.6 EMG50784.1 - 3.6 7.6 8.7 6.3 6.8 0.2 4.0 3 0 0 3 3 3 0 zinc-ribbon domain ARS2 PF04959.13 EMG50784.1 - 5.7 7.3 0.0 5.7 7.3 0.0 4.0 3 1 1 5 5 5 0 Arsenite-resistance protein 2 THOC2_N PF16134.5 EMG50785.1 - 5.7e-184 613.3 9.0 5.7e-184 613.3 9.0 2.8 3 0 0 3 3 3 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EMG50785.1 - 7.6e-69 232.2 7.0 7.6e-69 232.2 7.0 3.1 3 0 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EMG50785.1 - 6e-20 71.1 0.1 1.5e-19 69.8 0.1 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Tim17 PF02466.19 EMG50786.1 - 1.9e-30 105.5 8.0 2.8e-30 105.0 8.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3180 PF11377.8 EMG50786.1 - 5.7 7.1 9.2 29 4.8 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) Pkinase PF00069.25 EMG50787.1 - 8.8e-66 222.0 0.0 1.4e-65 221.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50787.1 - 2e-49 168.2 0.0 4.2e-49 167.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG50787.1 - 1.1e-06 28.2 0.2 0.00025 20.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EMG50787.1 - 3.2e-05 22.9 0.0 0.00012 21.0 0.0 2.0 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EMG50787.1 - 0.0038 16.2 8.6 0.0056 15.7 0.0 3.1 3 0 0 3 3 3 2 Haspin like kinase domain APH PF01636.23 EMG50787.1 - 0.029 14.3 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EMG50787.1 - 0.046 13.1 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mg_trans_NIPA PF05653.14 EMG50788.1 - 0.0029 16.8 25.4 0.017 14.3 11.3 2.4 3 0 0 3 3 3 2 Magnesium transporter NIPA DUF695 PF05117.12 EMG50788.1 - 0.016 15.4 0.1 0.31 11.2 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF695) RAMP4 PF06624.12 EMG50788.1 - 0.044 13.8 0.1 0.16 12.0 0.1 1.9 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 INSIG PF07281.12 EMG50788.1 - 0.066 12.9 1.6 1.6 8.3 0.1 3.2 3 1 0 3 3 3 0 Insulin-induced protein (INSIG) Tir_receptor_C PF07489.11 EMG50788.1 - 0.95 9.4 4.3 4.1 7.3 0.5 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus SpoU_methylase PF00588.19 EMG50789.1 - 3.2e-26 92.2 0.0 3.7e-25 88.7 0.0 2.1 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EMG50789.1 - 3.2e-11 43.3 0.1 8.2e-11 42.0 0.1 1.8 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF4432 PF14486.6 EMG50789.1 - 0.038 12.8 0.1 0.062 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) DUF676 PF05057.14 EMG50790.1 - 7.8e-40 136.7 0.0 1.3e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EMG50790.1 - 8.6e-08 32.3 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EMG50790.1 - 0.0051 16.6 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein DNA_pol_A_exo1 PF01612.20 EMG50790.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 3'-5' exonuclease Tudor_RapA PF18337.1 EMG50790.1 - 0.2 11.8 1.9 0.31 11.3 0.6 2.0 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain DUF4017 PF13209.6 EMG50790.1 - 0.41 10.6 2.3 0.88 9.5 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) SH3_1 PF00018.28 EMG50791.1 - 3.2e-16 58.7 0.1 5.5e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Ysc84 PF04366.12 EMG50791.1 - 1e-13 51.2 0.0 1.6e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_9 PF14604.6 EMG50791.1 - 2.9e-11 43.0 0.0 6.3e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMG50791.1 - 1.9e-10 40.2 0.0 4.3e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain LD_cluster3 PF18180.1 EMG50791.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 SLOG cluster3 family CDC45 PF02724.14 EMG50791.1 - 0.54 8.5 7.4 0.67 8.2 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein AA_permease_2 PF13520.6 EMG50792.1 - 3.4e-51 174.4 49.2 4.3e-51 174.1 49.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG50792.1 - 4.5e-34 117.9 43.9 6e-34 117.5 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L1 PF00687.21 EMG50793.1 - 1.3e-28 100.2 11.3 4.8e-28 98.3 11.3 1.7 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family GST_C PF00043.25 EMG50794.1 - 6.1e-21 74.5 0.0 1.1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMG50794.1 - 1.1e-18 67.3 0.0 2.5e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMG50794.1 - 2.7e-11 43.7 0.0 5.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMG50794.1 - 1.9e-10 40.8 0.0 4.1e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMG50794.1 - 0.00017 21.7 0.0 0.00048 20.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMG50794.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NPCC PF08058.11 EMG50795.1 - 2.2e-40 137.7 0.4 4.9e-40 136.6 0.4 1.6 1 0 0 1 1 1 1 Nuclear pore complex component IGPD PF00475.18 EMG50796.1 - 1.5e-60 203.7 0.8 2.3e-60 203.1 0.5 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.11 EMG50796.1 - 0.081 10.1 0.0 0.1 9.7 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase MDM10 PF12519.8 EMG50797.1 - 5.5e-114 381.6 4.0 6.3e-114 381.4 4.0 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 DUF835 PF05763.12 EMG50797.1 - 0.053 13.3 0.2 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF835) Mit_ribos_Mrp51 PF11709.8 EMG50798.1 - 7.9e-59 200.1 6.6 4.9e-58 197.5 6.6 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit SwrA PF17423.2 EMG50798.1 - 0.09 12.8 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Swarming motility protein Ribosomal_S6 PF01250.17 EMG50798.1 - 0.16 12.2 0.1 6.9 7.0 0.0 2.5 1 1 1 2 2 2 0 Ribosomal protein S6 DUF2420 PF10336.9 EMG50800.1 - 1.2e-24 86.4 8.8 3.5e-24 84.9 8.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) GTP_EFTU PF00009.27 EMG50801.1 - 1.5e-35 122.5 0.0 4.2e-35 121.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EMG50801.1 - 8.1e-19 67.6 0.0 1.4e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 EMG50801.1 - 5e-09 36.4 0.1 1.1e-08 35.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_C PF00679.24 EMG50801.1 - 3.8e-08 33.3 0.0 1.3e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus EFTUD2 PF16004.5 EMG50801.1 - 5.4e-06 27.0 8.0 0.035 14.7 1.8 2.5 1 1 1 2 2 2 2 116 kDa U5 small nuclear ribonucleoprotein component N-terminus MMR_HSR1 PF01926.23 EMG50801.1 - 3.2e-05 24.0 0.5 8e-05 22.7 0.2 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 EMG50801.1 - 0.0074 15.9 0.5 4.8 6.7 0.2 2.7 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 EMG50801.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 EMG50801.1 - 0.024 14.4 0.1 0.095 12.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ras PF00071.22 EMG50801.1 - 0.036 13.7 0.1 0.095 12.3 0.1 1.7 1 1 0 1 1 1 0 Ras family EFG_II PF14492.6 EMG50801.1 - 0.039 14.1 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Elongation Factor G, domain II ORC5_C PF14630.6 EMG50801.1 - 0.048 13.2 0.2 0.085 12.4 0.2 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EMG50801.1 - 0.061 13.7 0.0 0.15 12.5 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain Roc PF08477.13 EMG50801.1 - 0.071 13.3 0.0 0.29 11.4 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RNA_pol_Rpb4 PF03874.16 EMG50802.1 - 1.8e-31 109.0 10.6 5.4e-31 107.5 10.6 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb4 GCV_T PF01571.21 EMG50802.1 - 0.0042 16.5 0.0 0.0099 15.3 0.0 1.6 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DUF913 PF06025.12 EMG50802.1 - 0.012 14.6 0.5 0.015 14.3 0.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CENP-B_dimeris PF09026.10 EMG50802.1 - 0.016 15.6 3.2 0.13 12.7 3.7 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GRP PF07172.11 EMG50802.1 - 0.02 15.6 0.3 0.035 14.8 0.3 1.5 1 0 0 1 1 1 0 Glycine rich protein family BSP_II PF05432.11 EMG50802.1 - 0.1 12.3 9.5 0.14 11.8 9.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Cwf_Cwc_15 PF04889.12 EMG50802.1 - 0.11 12.2 6.1 0.18 11.5 6.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EMG50802.1 - 0.18 11.1 5.1 0.28 10.5 5.1 1.3 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 EMG50803.1 - 4.7e-51 173.7 0.2 1.5e-49 168.8 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50803.1 - 2e-21 76.4 0.0 4.2e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMG50803.1 - 0.00023 21.2 0.0 0.00046 20.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMG50803.1 - 0.0054 16.3 0.3 0.0054 16.3 0.3 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 EMG50803.1 - 0.03 13.9 0.0 0.03 13.9 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 EMG50803.1 - 0.035 13.5 0.4 0.069 12.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMG50803.1 - 0.039 13.3 0.3 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Kinase-like SWIRM PF04433.17 EMG50804.1 - 2.1e-29 101.7 0.2 6.6e-29 100.1 0.2 1.9 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EMG50804.1 - 5.8e-20 71.0 0.4 1.9e-19 69.4 0.4 1.9 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EMG50804.1 - 1.2e-09 38.3 0.0 3.2e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMG50804.1 - 1.9e-09 37.6 0.1 6.8e-09 35.8 0.1 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EMG50804.1 - 0.036 14.4 1.1 5.2 7.5 0.0 3.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ccdc124 PF06244.12 EMG50805.1 - 4e-32 111.5 0.8 7.1e-32 110.7 0.8 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 EMG50805.1 - 0.024 15.1 0.1 0.05 14.0 0.1 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box UcrQ PF02939.16 EMG50806.1 - 2e-31 107.8 1.3 2.3e-31 107.6 1.3 1.0 1 0 0 1 1 1 1 UcrQ family Ribosomal_L22 PF00237.19 EMG50807.1 - 1.1e-37 128.3 0.3 1.1e-37 128.3 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DUF3535 PF12054.8 EMG50808.1 - 6e-116 388.2 0.7 1.2e-114 384.0 1.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EMG50808.1 - 7.5e-64 215.6 0.1 1.8e-63 214.4 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMG50808.1 - 4.2e-18 65.7 0.0 1.3e-17 64.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EMG50808.1 - 3e-16 58.1 2.0 0.62 10.5 0.0 9.8 9 0 0 9 9 9 4 HEAT repeat Vac14_Fab1_bd PF12755.7 EMG50808.1 - 2e-07 31.5 0.1 0.032 14.8 0.0 5.5 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EMG50808.1 - 2.7e-06 27.7 0.2 0.2 12.0 0.0 5.6 4 1 2 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 EMG50808.1 - 6.8e-05 23.3 5.9 32 5.1 0.0 7.8 8 0 0 8 8 7 0 HEAT-like repeat DEAD PF00270.29 EMG50808.1 - 0.006 16.4 0.0 0.022 14.5 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase TAF6_C PF07571.13 EMG50808.1 - 0.0077 16.5 0.1 55 4.2 0.0 4.9 5 1 0 5 5 3 0 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 EMG50808.1 - 0.016 15.4 0.0 10 6.4 0.0 4.5 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 ERCC3_RAD25_C PF16203.5 EMG50808.1 - 0.025 13.8 0.0 0.025 13.8 0.0 1.8 2 0 0 2 2 1 0 ERCC3/RAD25/XPB C-terminal helicase CLASP_N PF12348.8 EMG50808.1 - 0.029 13.9 1.7 12 5.3 0.1 4.0 3 1 1 4 4 4 0 CLASP N terminal DUF3385 PF11865.8 EMG50808.1 - 0.029 14.3 2.0 0.092 12.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) DUF383 PF04063.14 EMG50808.1 - 0.039 13.6 0.4 0.22 11.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF383) Plasmod_dom_1 PF09715.10 EMG50808.1 - 0.12 12.4 0.1 0.58 10.3 0.1 2.2 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Mito_carr PF00153.27 EMG50809.1 - 1.4e-73 242.9 2.8 1.9e-26 91.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NpwBP PF12622.7 EMG50810.1 - 1.1e-08 35.7 0.3 1.1e-08 35.7 0.3 3.0 2 2 1 3 3 3 1 mRNA biogenesis factor Wbp11 PF09429.10 EMG50810.1 - 0.01 16.2 11.8 0.01 16.2 11.8 3.3 2 1 1 3 3 3 0 WW domain binding protein 11 Exonuc_VII_L PF02601.15 EMG50810.1 - 0.46 10.0 5.7 0.54 9.8 5.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0016 PF01169.19 EMG50811.1 - 1.1e-38 131.4 20.7 4e-19 68.7 4.6 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Presenilin PF01080.17 EMG50811.1 - 3.6e-05 22.7 0.1 6.4e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Presenilin Ion_trans PF00520.31 EMG50811.1 - 0.0052 16.0 1.6 0.0098 15.1 1.7 1.5 1 1 0 1 1 1 1 Ion transport protein TerC PF03741.16 EMG50811.1 - 0.15 11.7 13.0 0.07 12.8 3.5 2.5 1 1 1 2 2 2 0 Integral membrane protein TerC family Complex1_51K PF01512.17 EMG50812.1 - 2.5e-46 157.3 0.0 7.9e-46 155.7 0.0 1.8 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EMG50812.1 - 3e-29 100.9 0.1 7e-29 99.7 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EMG50812.1 - 5.8e-08 32.5 0.0 1.5e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 EMG50812.1 - 0.13 12.3 0.7 0.24 11.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Glyco_transf_15 PF01793.16 EMG50813.1 - 1.5e-111 372.8 11.7 1.8e-111 372.5 11.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5346 PF17281.2 EMG50813.1 - 0.23 11.5 1.2 0.49 10.4 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5346) Ebp2 PF05890.12 EMG50814.1 - 6.7e-90 301.3 21.1 6.7e-90 301.3 21.1 2.4 2 1 1 3 3 3 1 Eukaryotic rRNA processing protein EBP2 polyprenyl_synt PF00348.17 EMG50815.1 - 1.2e-93 312.8 0.1 1.6e-93 312.5 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase nsp8 PF08717.10 EMG50815.1 - 0.016 15.1 0.3 0.036 14.0 0.3 1.5 1 0 0 1 1 1 0 nsp8 replicase HMGL-like PF00682.19 EMG50816.1 - 2.7e-55 187.8 0.4 4.6e-55 187.0 0.2 1.5 2 0 0 2 2 2 1 HMGL-like FliG_N PF14842.6 EMG50816.1 - 0.058 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain ADH_N PF08240.12 EMG50817.1 - 1.3e-22 79.7 0.1 1.9e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMG50817.1 - 8.9e-10 38.6 0.0 5.5e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase zf-CXXC PF02008.20 EMG50817.1 - 0.026 14.5 1.8 0.049 13.7 1.8 1.4 1 0 0 1 1 1 0 CXXC zinc finger domain AlaDh_PNT_C PF01262.21 EMG50817.1 - 0.05 12.9 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_8 PF13183.6 EMG50817.1 - 0.073 13.5 1.9 1.5 9.4 1.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Myb_DNA-binding PF00249.31 EMG50818.1 - 3.1e-08 33.7 2.3 2.1e-07 31.0 2.3 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMG50818.1 - 0.0042 17.3 0.0 0.0098 16.1 0.0 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain Spt20 PF12090.8 EMG50818.1 - 0.28 10.8 5.7 0.42 10.2 5.7 1.3 1 0 0 1 1 1 0 Spt20 family Thiolase_N PF00108.23 EMG50819.1 - 7.9e-94 313.8 2.4 1.2e-93 313.3 2.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMG50819.1 - 4.2e-43 145.9 0.6 4.2e-43 145.9 0.6 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMG50819.1 - 9.5e-05 22.1 0.7 0.00019 21.1 0.7 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.25 EMG50821.1 - 5.6e-17 61.8 0.0 9.1e-13 48.1 0.0 3.2 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMG50821.1 - 5e-05 23.0 0.0 0.00016 21.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMG50821.1 - 0.0031 17.5 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 KR domain SUV3_C PF12513.8 EMG50822.1 - 2.9e-13 49.5 0.6 7.6e-13 48.2 0.6 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EMG50822.1 - 1.9e-12 47.5 0.5 7.2e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SKI PF01202.22 EMG50822.1 - 9.4e-10 38.8 0.0 4.6e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.6 EMG50822.1 - 7.5e-07 29.7 0.0 7.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMG50822.1 - 1.7e-05 25.0 0.0 8.6e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EMG50822.1 - 0.0005 19.9 0.0 0.0062 16.3 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 EMG50822.1 - 0.0025 18.2 0.0 0.0086 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMG50822.1 - 0.0044 16.8 0.1 0.2 11.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EMG50822.1 - 0.0047 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 EMG50822.1 - 0.0066 16.9 0.3 0.098 13.1 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EMG50822.1 - 0.022 14.2 0.1 4.7 6.6 0.2 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 EMG50822.1 - 0.023 14.9 0.2 0.65 10.3 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMG50822.1 - 0.045 14.1 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Suv3_C_1 PF18147.1 EMG50822.1 - 0.059 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 ComK PF06338.11 EMG50822.1 - 0.089 12.4 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 ComK protein AAA_19 PF13245.6 EMG50822.1 - 0.12 12.7 0.3 3.8 7.8 0.3 2.5 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EMG50822.1 - 0.13 12.2 0.8 2.3 8.0 0.0 2.8 2 1 1 3 3 3 0 Deoxynucleoside kinase T2SSE PF00437.20 EMG50822.1 - 0.25 10.4 0.6 6.1 5.8 0.3 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Pkinase PF00069.25 EMG50823.1 - 7.5e-66 222.2 0.2 1.9e-65 220.9 0.2 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50823.1 - 1.1e-39 136.3 0.0 2e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG50823.1 - 9.4e-07 28.4 0.0 9.4e-07 28.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Mur_ligase_M PF08245.12 EMG50824.1 - 3.6e-06 27.1 0.1 0.00013 22.1 0.1 2.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EMG50824.1 - 0.0012 19.1 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain GAGA_bind PF06217.12 EMG50826.1 - 0.055 13.7 7.5 0.083 13.2 7.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family WD40 PF00400.32 EMG50827.1 - 2.1e-29 101.1 21.3 6.1e-05 23.7 0.9 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50827.1 - 1.1e-10 41.7 1.2 0.43 10.9 0.0 5.4 4 3 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMG50827.1 - 1.6e-06 27.4 1.9 0.31 10.0 0.0 3.7 3 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EMG50827.1 - 3.1e-06 26.7 1.5 0.0092 15.3 0.0 3.3 2 1 1 3 3 3 2 WD40-like domain IZUMO PF15005.6 EMG50827.1 - 0.068 13.7 1.7 0.11 13.0 1.7 1.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated T2SS-T3SS_pil_N PF13629.6 EMG50827.1 - 0.08 12.7 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Pilus formation protein N terminal region YEATS PF03366.16 EMG50828.1 - 7.9e-22 77.0 0.0 1.3e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EMG50828.1 - 3e-06 27.3 0.3 6.6e-06 26.2 0.3 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation UBA2_C PF16195.5 EMG50828.1 - 0.38 11.5 1.8 1.3 9.7 0.4 2.0 1 1 1 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Aminotran_4 PF01063.19 EMG50829.1 - 7.7e-39 133.8 0.0 9.7e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Mo25 PF08569.11 EMG50830.1 - 7.1e-120 400.3 15.5 7.9e-120 400.1 15.5 1.0 1 0 0 1 1 1 1 Mo25-like EAP30 PF04157.16 EMG50831.1 - 3.4e-28 98.5 0.0 6.1e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EMG50831.1 - 2.2e-26 91.9 0.8 4.8e-26 90.8 0.8 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 EMG50831.1 - 2.3e-15 55.8 1.9 2.3e-15 55.8 1.9 2.4 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 EMG50831.1 - 0.0042 17.1 0.4 0.0042 17.1 0.4 2.0 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 EMG50831.1 - 0.017 15.9 5.9 0.025 15.3 4.8 2.0 2 0 0 2 2 1 0 zinc-ribbon family zf-RanBP PF00641.18 EMG50831.1 - 0.02 14.2 2.1 0.02 14.2 2.1 3.0 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others bPH_3 PF14470.6 EMG50831.1 - 0.039 14.3 0.7 0.24 11.8 0.1 2.6 2 0 0 2 2 2 0 Bacterial PH domain FlgN PF05130.12 EMG50831.1 - 0.048 14.2 0.4 0.048 14.2 0.4 2.1 2 0 0 2 2 2 0 FlgN protein DUF35_N PF12172.8 EMG50831.1 - 0.057 13.3 3.1 0.061 13.2 0.3 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Fe-ADH_2 PF13685.6 EMG50831.1 - 0.064 12.9 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase Nudix_N_2 PF14803.6 EMG50831.1 - 1.8 8.5 3.8 2.1 8.4 0.1 2.8 3 0 0 3 3 3 0 Nudix N-terminal Pkinase PF00069.25 EMG50832.1 - 2.6e-88 295.8 0.8 6.7e-59 199.4 0.1 4.1 5 1 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50832.1 - 1.6e-42 145.6 3.0 1.1e-26 93.6 0.0 3.9 4 0 0 4 4 4 2 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EMG50832.1 - 0.28 10.7 0.0 0.28 10.7 0.0 3.8 4 0 0 4 4 4 0 PhoP regulatory network protein YrbL TFIIA PF03153.13 EMG50832.1 - 1 9.3 54.9 0.016 15.2 11.3 2.6 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 EMG50833.1 - 2.1e-61 207.6 0.3 4e-61 206.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50833.1 - 5.2e-23 81.6 1.7 9.1e-22 77.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EMG50833.1 - 0.0007 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EMG50833.1 - 0.012 15.6 1.1 0.039 13.9 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMG50833.1 - 0.023 14.3 0.0 0.023 14.3 0.0 2.4 3 1 0 3 3 3 0 Choline/ethanolamine kinase FLILHELTA PF10306.9 EMG50834.1 - 1.1e-27 96.2 0.8 2.1e-27 95.4 0.4 1.7 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EMG50834.1 - 0.038 14.6 0.6 0.088 13.4 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) ADH_N PF08240.12 EMG50835.1 - 3.5e-23 81.6 0.0 4.7e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMG50835.1 - 4.8e-05 23.3 0.0 9.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-CXXC PF02008.20 EMG50835.1 - 0.022 14.8 1.7 0.036 14.1 1.7 1.3 1 0 0 1 1 1 0 CXXC zinc finger domain AlaDh_PNT_C PF01262.21 EMG50835.1 - 0.054 12.8 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aminotran_3 PF00202.21 EMG50836.1 - 3.6e-102 342.0 0.0 4.2e-102 341.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMG50836.1 - 0.0016 17.7 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II TRF PF08558.10 EMG50837.1 - 2.3e-77 259.8 0.0 2.3e-77 259.8 0.0 2.5 3 1 0 3 3 3 1 Telomere repeat binding factor (TRF) Mito_carr PF00153.27 EMG50838.1 - 1e-61 204.9 0.4 2.9e-25 88.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein B12D PF06522.11 EMG50838.1 - 0.00012 21.9 0.8 0.00023 20.9 0.0 1.8 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Ccdc124 PF06244.12 EMG50839.1 - 1.9e-32 112.5 3.3 2.9e-32 111.9 3.3 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 EMG50839.1 - 0.025 15.0 0.1 0.063 13.7 0.1 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box Transcrip_reg PF01709.20 EMG50840.1 - 7.9e-56 189.2 0.4 8.8e-56 189.0 0.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator Cas_APE2256 PF09651.10 EMG50840.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Flt3_lig PF02947.14 EMG50840.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 flt3 ligand AA_permease_2 PF13520.6 EMG50841.1 - 0.0014 17.6 4.1 0.0016 17.4 4.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF485 PF04341.12 EMG50841.1 - 0.068 13.1 4.9 0.044 13.7 2.6 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF679 PF05078.12 EMG50841.1 - 0.13 12.2 0.3 0.18 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF679) Methyltransf_16 PF10294.9 EMG50842.1 - 4.7e-16 59.0 0.0 8.1e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EMG50842.1 - 0.0045 16.9 0.0 0.0077 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain 4HBT_3 PF13622.6 EMG50843.1 - 1e-34 120.9 0.0 1.3e-34 120.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMG50843.1 - 2e-17 63.3 1.9 1.6e-10 41.0 0.3 3.7 2 1 1 3 3 3 2 Acyl-CoA thioesterase CAF1C_H4-bd PF12265.8 EMG50844.1 - 4e-22 78.3 0.3 1.9e-21 76.1 0.3 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EMG50844.1 - 3.4e-08 34.0 15.6 0.018 15.9 1.7 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50844.1 - 4.7e-07 30.0 1.5 0.53 10.6 0.0 4.8 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2829 PF11195.8 EMG50844.1 - 0.051 13.8 0.6 0.72 10.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) Mt_ATP-synt_B PF05405.14 EMG50845.1 - 5.5e-51 172.4 10.3 6.6e-51 172.2 10.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TBCA PF02970.16 EMG50845.1 - 0.91 9.9 10.2 1.2 9.5 0.2 2.7 1 1 2 3 3 3 0 Tubulin binding cofactor A DUF2175 PF09943.9 EMG50845.1 - 3 8.2 6.2 1.8 8.9 2.6 2.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) cwf18 PF08315.12 EMG50846.1 - 1.6e-06 28.9 8.9 0.00036 21.2 1.2 2.1 2 0 0 2 2 2 2 cwf18 pre-mRNA splicing factor Paramyxo_ncap PF00973.19 EMG50846.1 - 4.4 6.1 6.4 4.8 6.0 6.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Sec63 PF02889.16 EMG50847.1 - 2.3e-29 102.3 0.1 4.1e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EMG50847.1 - 8.6e-25 87.5 0.1 2.5e-24 86.0 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMG50847.1 - 3.5e-14 53.1 0.1 1.5e-12 47.8 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMG50847.1 - 7.9e-14 52.0 0.1 3.4e-13 50.0 0.1 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EMG50847.1 - 0.002 18.5 0.7 0.047 14.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain DNA_pol_lambd_f PF10391.9 EMG50847.1 - 0.061 13.2 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda T2SSE PF00437.20 EMG50847.1 - 0.076 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein HHH_5 PF14520.6 EMG50847.1 - 0.1 13.2 0.0 0.33 11.6 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain RRM_1 PF00076.22 EMG50848.1 - 5.7e-15 54.9 10.6 9e-10 38.2 0.1 4.7 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 EMG50848.1 - 0.084 12.5 0.0 0.38 10.4 0.0 2.2 1 0 0 1 1 1 0 Sporulation protein family 7 Sds3 PF08598.11 EMG50849.1 - 4.1e-46 157.7 0.1 4.1e-46 157.7 0.1 3.8 2 1 1 3 3 3 1 Sds3-like MRP-L47 PF06984.13 EMG50849.1 - 0.12 12.5 2.2 6.7 6.9 0.1 3.1 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) fn3_2 PF16893.5 EMG50850.1 - 1.1e-36 124.9 0.3 1.9e-36 124.1 0.3 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EMG50850.1 - 8.9e-24 83.2 0.1 1.4e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 EMG50850.1 - 2e-13 50.5 0.1 4.6e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EMG50850.1 - 3e-06 27.1 0.0 5.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 EMG50850.1 - 0.0022 18.2 0.1 0.0022 18.2 0.1 3.0 2 1 0 3 3 3 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 EMG50850.1 - 0.012 16.0 0.0 0.031 14.7 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain fn3_4 PF16794.5 EMG50850.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Fibronectin-III type domain FA_hydroxylase PF04116.13 EMG50852.1 - 9.3e-22 77.8 8.5 9.3e-22 77.8 8.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Wzy_C_2 PF11846.8 EMG50852.1 - 0.0073 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Virulence factor membrane-bound polymerase, C-terminal PAS_8 PF13188.7 EMG50852.1 - 0.17 11.9 0.0 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 PAS domain TRAPP PF04051.16 EMG50853.1 - 1.1e-33 116.0 0.0 1.3e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DDE_Tnp_ISAZ013 PF07592.11 EMG50853.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Y_phosphatase PF00102.27 EMG50854.1 - 2e-59 201.0 1.0 2.9e-59 200.5 1.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EMG50854.1 - 0.0001 22.2 0.1 0.0044 16.8 0.0 2.7 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EMG50854.1 - 0.019 15.1 0.0 0.17 12.0 0.0 2.4 2 2 1 3 3 3 0 Inositol hexakisphosphate Oxidored_FMN PF00724.20 EMG50855.1 - 3.8e-82 276.3 0.0 4.3e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MGS PF02142.22 EMG50855.1 - 0.064 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 MGS-like domain zf-AN1 PF01428.16 EMG50856.1 - 7.1e-10 38.9 11.6 1.2e-09 38.1 11.6 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_4 PF18036.1 EMG50856.1 - 6.6e-06 26.1 1.5 0.017 15.2 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-like domain ubiquitin PF00240.23 EMG50856.1 - 9.4e-05 22.1 0.1 0.00032 20.4 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EMG50856.1 - 0.00033 21.2 0.0 0.0092 16.5 0.1 2.1 1 1 1 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 EMG50856.1 - 0.014 15.2 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Transp_Tc5_C PF04236.15 EMG50856.1 - 0.03 14.7 4.4 0.06 13.7 4.4 1.5 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Fe_dep_repr_C PF02742.15 EMG50856.1 - 0.062 13.4 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Nro1 PF12753.7 EMG50857.1 - 5.2e-158 526.3 37.1 6.7e-158 526.0 37.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 RNase_J_C PF17770.1 EMG50857.1 - 0.51 11.4 8.8 35 5.5 0.0 4.9 5 0 0 5 5 5 0 Ribonuclease J C-terminal domain TP_methylase PF00590.20 EMG50858.1 - 1.1e-44 152.9 0.0 1.6e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EMG50858.1 - 1.2e-09 38.6 0.0 2.7e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 EMG50858.1 - 2.2e-07 30.2 0.0 4.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 EMG50858.1 - 2.1e-05 24.1 1.1 0.00037 20.1 0.1 2.9 2 1 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Aminotran_1_2 PF00155.21 EMG50859.1 - 1.1e-66 225.5 0.0 1.2e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMG50859.1 - 0.0032 16.1 0.1 0.0059 15.2 0.1 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 EMG50859.1 - 0.0068 15.0 0.0 0.0092 14.5 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 EMG50859.1 - 0.0078 15.2 0.1 0.017 14.1 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMG50859.1 - 0.018 14.3 0.1 0.037 13.3 0.1 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EMG50859.1 - 0.07 12.4 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase AA_permease_2 PF13520.6 EMG50860.1 - 2.3e-47 161.8 31.1 2.6e-47 161.6 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG50860.1 - 2.5e-12 46.2 25.3 3.6e-12 45.6 25.3 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2721 PF11026.8 EMG50860.1 - 0.079 12.9 0.0 0.079 12.9 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) INSIG PF07281.12 EMG50860.1 - 0.21 11.2 4.0 0.074 12.7 0.6 2.1 2 1 0 2 2 2 0 Insulin-induced protein (INSIG) CBFD_NFYB_HMF PF00808.23 EMG50861.1 - 3.6e-15 56.0 2.2 5.8e-15 55.3 2.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMG50861.1 - 2.3e-05 24.7 1.9 2.9e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Orthopox_B11R PF07033.11 EMG50861.1 - 0.029 14.1 1.4 0.029 14.1 1.4 2.7 2 2 0 2 2 2 0 Orthopoxvirus B11R protein CENP-T_C PF15511.6 EMG50861.1 - 0.054 13.6 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Abhydrolase_1 PF00561.20 EMG50862.1 - 5.2e-22 78.7 0.1 1.2e-17 64.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMG50862.1 - 3.1e-16 60.6 0.0 4.6e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMG50862.1 - 1.4e-10 40.9 0.0 4.9e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EMG50862.1 - 2.1e-07 30.9 0.1 0.00012 21.8 0.0 2.3 1 1 1 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 EMG50862.1 - 7.3e-07 29.5 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 EMG50862.1 - 0.0028 16.4 0.0 0.0085 14.8 0.0 1.6 1 1 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 EMG50862.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EMG50862.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 EMG50862.1 - 0.07 12.5 0.1 1.9 7.8 0.0 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) baeRF_family5 PF18846.1 EMG50862.1 - 0.076 13.2 0.1 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 Esterase PF00756.20 EMG50862.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase SGTA_dimer PF16546.5 EMG50863.1 - 4.3e-25 87.3 4.9 4.3e-25 87.3 4.9 1.9 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 EMG50863.1 - 1.1e-17 63.0 1.4 3.3e-07 29.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMG50863.1 - 3e-16 58.2 1.0 6e-05 22.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMG50863.1 - 5.5e-14 51.6 2.3 1.2e-05 24.8 0.1 3.1 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 EMG50863.1 - 3.9e-09 36.0 6.5 0.0026 17.8 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMG50863.1 - 8.3e-09 35.2 0.6 0.0024 18.1 0.1 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EMG50863.1 - 2.3e-07 30.4 1.2 0.022 14.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMG50863.1 - 5.8e-06 26.7 0.8 0.094 13.6 0.1 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMG50863.1 - 8.4e-06 26.3 0.7 0.0023 18.5 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMG50863.1 - 6.4e-05 22.7 0.2 0.23 11.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMG50863.1 - 6.8e-05 23.1 0.7 0.01 16.1 0.1 3.0 3 1 0 3 3 2 1 Tetratricopeptide repeat STI1 PF17830.1 EMG50863.1 - 8.7e-05 22.4 12.7 0.0021 17.9 11.0 2.7 2 0 0 2 2 2 1 STI1 domain TPR_19 PF14559.6 EMG50863.1 - 0.00014 22.3 0.9 0.28 11.7 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 EMG50863.1 - 0.0094 16.4 0.1 0.21 12.0 0.0 2.4 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 EMG50863.1 - 0.025 13.8 0.3 0.11 11.7 0.3 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMG50863.1 - 0.037 14.7 3.4 22 5.9 0.8 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EMG50863.1 - 0.046 13.9 0.1 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EMG50863.1 - 0.18 11.9 4.4 3.7 7.7 0.1 3.8 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain VPS9 PF02204.18 EMG50864.1 - 3.4e-14 52.9 0.8 1.2e-13 51.1 0.8 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EMG50864.1 - 0.005 17.1 0.4 1.1 9.7 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMG50864.1 - 0.0065 17.0 1.4 1.6 9.4 0.1 3.4 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMG50864.1 - 0.087 13.4 0.1 59 4.4 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Retrotrans_gag PF03732.17 EMG50864.1 - 0.16 12.2 0.7 0.98 9.7 0.6 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein AA_permease_2 PF13520.6 EMG50865.1 - 1.2e-45 156.1 34.7 1.3e-45 156.0 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG50865.1 - 5.7e-10 38.4 29.7 7.4e-10 38.0 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease Cul7 PF11515.8 EMG50865.1 - 0.083 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 ADH_zinc_N_2 PF13602.6 EMG50866.1 - 1.2e-18 68.5 0.0 1.7e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMG50866.1 - 4e-10 39.8 0.0 8.8e-10 38.7 0.0 1.5 1 1 1 2 2 2 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 EMG50866.1 - 0.049 12.9 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 EMG50866.1 - 0.074 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TGT_C2 PF14810.6 EMG50866.1 - 0.076 13.2 0.0 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 Patch-forming domain C2 of tRNA-guanine transglycosylase KR PF08659.10 EMG50866.1 - 0.11 12.4 0.3 0.4 10.6 0.2 1.8 2 0 0 2 2 2 0 KR domain AA_permease_2 PF13520.6 EMG50867.1 - 3e-07 29.6 4.7 3.7e-07 29.3 4.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF485 PF04341.12 EMG50867.1 - 1.1 9.2 7.8 0.58 10.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 ADH_N PF08240.12 EMG50868.1 - 1.3e-05 25.0 0.0 1.7e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EMG50868.1 - 0.034 14.1 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase RRM_Rrp7 PF17799.1 EMG50870.1 - 3.6e-53 179.7 3.8 3.6e-53 179.7 3.8 1.8 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 EMG50870.1 - 1.4e-29 102.7 14.6 2.5e-29 101.8 14.6 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 EMG50870.1 - 0.01 15.7 0.1 2 8.3 0.0 2.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kdo PF06293.14 EMG50870.1 - 0.079 12.3 0.1 0.079 12.3 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF45 PF01863.17 EMG50870.1 - 0.17 11.9 5.4 0.3 11.1 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 CENP-H PF05837.12 EMG50870.1 - 1.2 9.6 10.6 8.1 6.9 5.5 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Hydrolase PF00702.26 EMG50871.1 - 4.8e-15 56.4 0.2 7.4e-15 55.8 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMG50871.1 - 2.2e-14 54.3 0.0 3.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMG50871.1 - 7.7e-09 35.7 0.1 7.7e-09 35.7 0.1 2.6 2 2 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMG50871.1 - 1.6e-05 25.0 3.7 0.00088 19.4 0.8 3.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 EMG50871.1 - 0.029 13.9 0.1 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Aha1_N PF09229.11 EMG50871.1 - 0.039 14.2 1.8 0.26 11.5 0.1 2.4 1 1 1 2 2 2 0 Activator of Hsp90 ATPase, N-terminal CRAL_TRIO PF00650.20 EMG50872.1 - 2.7e-36 124.7 0.0 4.4e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMG50872.1 - 6.6e-18 64.6 1.4 1.2e-17 63.8 1.4 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NNMT_PNMT_TEMT PF01234.17 EMG50872.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Aldedh PF00171.22 EMG50873.1 - 8.1e-160 532.3 4.7 2e-129 432.1 1.8 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 EMG50873.1 - 0.042 13.3 0.0 6.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) FAD-oxidase_C PF02913.19 EMG50874.1 - 9.1e-55 186.0 0.0 2.9e-54 184.4 0.0 1.8 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMG50874.1 - 8.8e-31 106.5 0.0 2.1e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain zf-RRN7 PF11781.8 EMG50874.1 - 1e-08 34.7 0.4 2.2e-08 33.6 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 XhlA PF10779.9 EMG50874.1 - 0.99 9.7 3.5 1.5 9.1 0.2 2.9 2 0 0 2 2 2 0 Haemolysin XhlA RabGAP-TBC PF00566.18 EMG50875.1 - 1.9e-37 129.0 0.2 2.6e-37 128.6 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 EMG50876.1 - 2.3e-11 43.3 0.7 0.00023 20.9 0.0 3.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMG50876.1 - 0.02 14.8 0.0 0.081 12.8 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif HSP70 PF00012.20 EMG50877.1 - 6.5e-57 193.1 16.5 6.5e-57 193.1 16.5 2.6 2 1 0 2 2 2 1 Hsp70 protein DUF4258 PF14076.6 EMG50877.1 - 0.048 14.0 0.0 1.4 9.3 0.0 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4258) CPSF100_C PF13299.6 EMG50877.1 - 3.9 7.6 8.5 0.44 10.7 0.2 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4050 PF13259.6 EMG50877.1 - 4.4 7.6 9.2 0.19 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Pribosyltran PF00156.27 EMG50879.1 - 1.4e-08 34.4 0.0 3e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Fe-ADH PF00465.19 EMG50879.1 - 0.012 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase UFD1 PF03152.14 EMG50880.1 - 6.5e-72 240.6 0.0 8.2e-72 240.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 IBN_N PF03810.19 EMG50881.1 - 2.5e-10 40.1 0.0 1.7e-09 37.4 0.0 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.10 EMG50881.1 - 8.8e-09 34.7 7.5 8.8e-09 34.7 7.5 4.3 3 2 1 4 4 4 2 Cse1 TRAPPC-Trs85 PF12739.7 EMG50881.1 - 0.087 11.8 0.4 0.19 10.7 0.1 1.6 2 0 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF3385 PF11865.8 EMG50881.1 - 0.2 11.5 0.1 0.2 11.5 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3385) Sec7_N PF12783.7 EMG50881.1 - 0.31 10.9 5.2 10 6.0 0.5 4.0 3 1 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SPG48 PF14764.6 EMG50881.1 - 0.42 11.1 4.0 20 5.7 0.3 3.9 2 1 1 3 3 3 0 AP-5 complex subunit, vesicle trafficking Hydantoinase_B PF02538.14 EMG50882.1 - 3.6e-207 688.9 0.0 4.6e-207 688.5 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EMG50882.1 - 7.2e-94 314.3 0.0 1.3e-93 313.5 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMG50882.1 - 5.4e-53 179.3 0.5 2e-51 174.2 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Ribo_biogen_C PF04034.13 EMG50882.1 - 8.5e-52 174.2 0.0 1.6e-51 173.3 0.0 1.5 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EMG50882.1 - 2.2e-13 49.8 0.2 7.3e-13 48.1 0.5 1.8 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI PH PF00169.29 EMG50883.1 - 0.6 10.6 0.1 0.6 10.6 0.1 2.7 3 0 0 3 3 3 0 PH domain Ribonuc_red_sm PF00268.21 EMG50884.1 - 3.7e-120 400.6 4.0 5.2e-120 400.1 4.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Formyl_trans_N PF00551.19 EMG50885.1 - 4.5e-45 153.6 0.4 4.9e-44 150.2 0.4 1.9 1 1 0 1 1 1 1 Formyl transferase Iso_dh PF00180.20 EMG50886.1 - 1.7e-100 336.5 0.0 2e-100 336.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_transf_22 PF03901.17 EMG50887.1 - 3.1e-63 214.5 35.7 4.1e-63 214.1 35.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family AAA PF00004.29 EMG50888.1 - 1.2e-45 155.2 0.1 3.9e-45 153.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EMG50888.1 - 7.8e-10 38.6 0.2 5.5e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EMG50888.1 - 6.9e-09 36.1 0.0 1.5e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EMG50888.1 - 1.7e-08 34.6 0.1 6.9e-08 32.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMG50888.1 - 3.1e-08 34.2 0.1 3.4e-05 24.3 0.0 3.1 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EMG50888.1 - 4.1e-05 23.9 0.9 0.0053 17.0 0.0 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EMG50888.1 - 6.4e-05 22.2 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EMG50888.1 - 0.00029 20.6 0.0 0.00083 19.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EMG50888.1 - 0.00031 20.8 0.1 0.0011 19.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 EMG50888.1 - 0.00046 19.9 0.1 0.0011 18.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain NTPase_1 PF03266.15 EMG50888.1 - 0.00086 19.3 0.0 0.0039 17.1 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 EMG50888.1 - 0.00087 19.8 0.0 0.0051 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EMG50888.1 - 0.0014 18.2 0.1 0.0096 15.4 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 EMG50888.1 - 0.0019 18.0 0.0 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EMG50888.1 - 0.0026 17.9 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EMG50888.1 - 0.0041 17.1 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EMG50888.1 - 0.0046 16.7 0.6 0.017 14.9 0.0 2.4 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EMG50888.1 - 0.0048 17.3 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EMG50888.1 - 0.0058 15.9 0.0 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain TniB PF05621.11 EMG50888.1 - 0.0069 15.8 0.0 0.52 9.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein NACHT PF05729.12 EMG50888.1 - 0.0079 16.1 0.2 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 EMG50888.1 - 0.0085 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EMG50888.1 - 0.0094 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMG50888.1 - 0.016 15.6 0.1 0.39 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMG50888.1 - 0.016 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EMG50888.1 - 0.025 14.3 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EMG50888.1 - 0.032 13.9 0.1 0.28 10.9 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 EMG50888.1 - 0.039 13.3 0.3 0.86 8.9 0.0 2.3 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 EMG50888.1 - 0.045 13.6 1.0 0.44 10.4 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EMG50888.1 - 0.046 13.5 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMG50888.1 - 0.064 12.8 1.4 0.24 10.9 0.1 2.4 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EMG50888.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Bac_DnaA PF00308.18 EMG50888.1 - 0.091 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein Viral_Hsp90 PF03225.14 EMG50888.1 - 0.13 10.8 0.2 0.18 10.3 0.2 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue ABC_tran PF00005.27 EMG50888.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.9 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 EMG50888.1 - 0.21 10.6 0.0 0.38 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 EMG50888.1 - 0.34 11.4 2.2 2.9 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain She9_MDM33 PF05546.11 EMG50889.1 - 1.3e-88 296.0 11.1 1.3e-88 296.0 11.1 2.2 2 0 0 2 2 2 1 She9 / Mdm33 family HhH-GPD PF00730.25 EMG50889.1 - 0.035 14.6 0.1 17 5.9 0.1 2.7 2 1 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein PAS_9 PF13426.7 EMG50889.1 - 0.67 10.2 2.6 6.1 7.2 0.0 2.8 2 2 0 2 2 2 0 PAS domain CBF PF03914.17 EMG50889.1 - 4.2 7.4 6.4 0.28 11.2 0.6 2.0 3 0 0 3 3 3 0 CBF/Mak21 family ACR_tran PF00873.19 EMG50889.1 - 6.7 4.2 6.6 3.7 5.1 4.3 1.5 1 1 0 1 1 1 0 AcrB/AcrD/AcrF family PI-PLC-X PF00388.19 EMG50890.1 - 6.5e-19 68.0 0.0 1.1e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain CENP-Q PF13094.6 EMG50891.1 - 3.5e-25 89.1 4.0 4.2e-25 88.9 1.1 2.0 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit P53_tetramer PF07710.11 EMG50891.1 - 0.13 11.7 2.9 0.91 8.9 0.1 2.6 1 1 1 2 2 2 0 P53 tetramerisation motif DNA_ligase_A_M PF01068.21 EMG50892.1 - 1.4e-59 201.2 0.4 2.9e-59 200.1 0.4 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EMG50892.1 - 1e-28 100.8 0.3 4.7e-28 98.7 0.3 2.1 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 EMG50892.1 - 9.6e-17 61.2 1.0 8.4e-11 42.1 0.1 3.0 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 EMG50892.1 - 2.6e-11 44.1 0.1 6.1e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 EMG50892.1 - 5.1e-11 42.8 1.6 6.4e-10 39.3 0.4 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.19 EMG50892.1 - 1.3e-06 28.4 0.7 0.013 15.3 0.1 3.1 2 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain DNA_ligase_A_C PF04679.15 EMG50892.1 - 1.4e-05 25.6 0.0 3.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region GTP_EFTU PF00009.27 EMG50893.1 - 2.6e-67 226.1 0.5 3.7e-67 225.6 0.5 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EMG50893.1 - 2.3e-33 114.5 0.0 9.7e-33 112.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EMG50893.1 - 3.7e-22 78.2 0.0 9e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EMG50893.1 - 2.3e-13 50.0 0.0 6.6e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EMG50893.1 - 4.1e-13 49.5 0.4 1.3e-12 48.0 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMG50893.1 - 0.00036 20.6 0.3 0.0008 19.5 0.3 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ribonuc_red_lgC PF02867.15 EMG50894.1 - 2e-190 633.8 0.0 2.8e-190 633.3 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EMG50894.1 - 1e-21 76.7 0.0 2.6e-21 75.4 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EMG50894.1 - 1e-16 61.2 0.5 3.1e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain LCCL PF03815.19 EMG50895.1 - 4e-05 23.6 0.1 9.4e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 LCCL domain DDHD PF02862.17 EMG50896.1 - 7.5e-43 147.3 0.1 7.5e-43 147.3 0.1 3.3 2 2 0 2 2 2 1 DDHD domain Lipase_3 PF01764.25 EMG50896.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DDHD PF02862.17 EMG50897.1 - 1.4e-46 159.4 0.0 8.2e-46 157.0 0.0 2.1 2 0 0 2 2 2 1 DDHD domain Lipase_3 PF01764.25 EMG50897.1 - 0.02 14.8 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 EMG50897.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF999 PF06198.11 EMG50897.1 - 0.083 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF999) PGAP1 PF07819.13 EMG50897.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Sugar_tr PF00083.24 EMG50898.1 - 6.3e-72 242.9 11.2 9.5e-72 242.3 11.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG50898.1 - 5.9e-26 91.2 19.7 3.5e-16 59.1 0.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu_amine_oxid PF01179.20 EMG50899.1 - 3e-141 471.1 0.1 3.7e-141 470.8 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain RNA_Me_trans PF04252.13 EMG50899.1 - 2e-62 210.3 0.0 3.3e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Cu_amine_oxidN3 PF02728.16 EMG50899.1 - 7.9e-25 87.2 0.2 2.2e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EMG50899.1 - 2e-19 69.6 0.0 4.1e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF3810 PF12725.7 EMG50900.1 - 0.22 10.8 4.0 0.12 11.7 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) ATP19 PF11022.8 EMG50901.1 - 1.8e-10 41.0 0.0 2.3e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit K PRP3 PF08572.10 EMG50902.1 - 2.8e-69 233.3 16.0 2.8e-69 233.3 16.0 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EMG50902.1 - 1.2e-34 119.5 2.6 1.2e-34 119.5 2.6 3.9 2 2 0 2 2 2 1 Protein of unknown function (DUF1115) HECT PF00632.25 EMG50903.1 - 3e-94 316.0 0.0 6.8e-94 314.8 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 EMG50903.1 - 3.2e-90 303.1 6.2 3.2e-90 303.1 6.2 3.0 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 EMG50903.1 - 2.2e-59 201.3 0.0 2.2e-59 201.3 0.0 4.8 5 1 0 5 5 5 1 Domain of Unknown Function (DUF913) UBM PF14377.6 EMG50903.1 - 8.9e-19 66.3 2.8 2.7e-08 33.0 0.9 2.7 2 0 0 2 2 2 2 Ubiquitin binding region U79_P34 PF03064.16 EMG50903.1 - 0.11 11.8 11.8 0.27 10.6 11.8 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AIF_C PF14721.6 EMG50903.1 - 0.45 10.9 8.6 1 9.7 0.6 2.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TPPII_N PF12583.8 EMG50903.1 - 0.62 10.6 5.2 1.6 9.3 2.5 2.5 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal DUF1682 PF07946.14 EMG50903.1 - 1.4 8.0 15.7 3.3 6.8 15.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SSP160 PF06933.11 EMG50903.1 - 2.9 6.0 13.6 4.8 5.3 13.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-C2H2_6 PF13912.6 EMG50904.1 - 0.0016 18.3 1.4 0.0016 18.3 1.4 3.7 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EMG50904.1 - 0.0048 17.6 31.8 0.042 14.7 2.7 5.3 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EMG50904.1 - 0.017 15.6 3.5 0.017 15.6 3.5 5.3 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EMG50904.1 - 0.1 12.9 0.1 0.1 12.9 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding ELO PF01151.18 EMG50905.1 - 5.6e-59 199.7 27.4 6.7e-59 199.4 27.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CNH PF00780.22 EMG50906.1 - 4.2e-70 236.5 0.3 8.7e-70 235.5 0.0 1.7 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.20 EMG50906.1 - 3.3e-39 135.0 1.2 3.3e-39 135.0 1.2 2.3 2 1 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 EMG50906.1 - 4.9e-26 91.4 0.4 4.9e-26 91.4 0.4 3.2 4 0 0 4 4 4 1 Pleckstrin homology domain DEP PF00610.21 EMG50906.1 - 3.5e-13 49.4 0.1 9.3e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) His_Phos_1 PF00300.22 EMG50907.1 - 2.3e-34 118.8 0.1 3.1e-29 102.1 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) PITH PF06201.13 EMG50908.1 - 1.5e-33 116.2 0.6 2e-33 115.7 0.6 1.2 1 0 0 1 1 1 1 PITH domain Aa_trans PF01490.18 EMG50909.1 - 9.6e-95 317.7 31.1 1.1e-94 317.5 31.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 EMG50909.1 - 0.37 9.6 37.0 0.82 8.4 36.2 1.9 1 1 0 1 1 1 0 Amino acid permease Nucleoporin_FG PF13634.6 EMG50910.1 - 2.9e-19 69.7 117.7 9.1e-07 29.6 34.0 5.4 1 1 4 5 5 5 5 Nucleoporin FG repeat region Nsp1_C PF05064.13 EMG50911.1 - 1.1e-37 128.4 7.2 1.1e-37 128.4 7.2 2.6 3 0 0 3 3 3 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EMG50911.1 - 5.6e-09 36.7 54.2 1.2e-07 32.4 14.2 3.9 2 1 1 3 3 3 2 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 EMG50911.1 - 0.017 13.7 40.0 0.036 12.6 5.1 3.2 2 1 1 3 3 3 0 Nucleoporin FG repeated region APG6_N PF17675.1 EMG50911.1 - 0.42 11.1 20.8 0.059 13.9 3.9 2.6 2 1 1 3 3 3 0 Apg6 coiled-coil region CorA PF01544.18 EMG50911.1 - 3.1 7.0 9.7 3.1 7.0 1.3 2.9 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein DASH_Spc19 PF08287.11 EMG50911.1 - 3.8 7.4 15.6 1.6 8.6 7.2 2.5 1 1 1 2 2 2 0 Spc19 HATPase_c PF02518.26 EMG50912.1 - 1.8e-29 102.5 0.2 4.6e-29 101.2 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMG50912.1 - 1.1e-18 67.4 0.1 4.1e-18 65.6 0.1 2.1 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase PF00069.25 EMG50912.1 - 2e-17 63.5 0.0 4.5e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain HisKA PF00512.25 EMG50912.1 - 8.5e-14 51.3 0.1 1.7e-12 47.2 0.0 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 EMG50912.1 - 1.2e-12 48.6 0.0 2.9e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Pkinase_Tyr PF07714.17 EMG50912.1 - 4e-11 42.7 0.0 8.7e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_3 PF13492.6 EMG50912.1 - 7.9e-09 36.0 0.0 2e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EMG50912.1 - 6.2e-08 33.0 0.0 2.4e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 EMG50912.1 - 1.1e-05 26.0 0.0 9.3e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 GAF domain AAA_7 PF12775.7 EMG50912.1 - 0.013 15.1 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Cas_Cas4 PF01930.17 EMG50912.1 - 0.033 14.3 0.5 1.9 8.6 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF83 RsgA_GTPase PF03193.16 EMG50912.1 - 0.073 13.0 0.1 0.62 9.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EMG50912.1 - 0.16 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Snf7 PF03357.21 EMG50913.1 - 6.9e-28 97.4 17.7 9e-28 97.0 17.7 1.1 1 0 0 1 1 1 1 Snf7 DUF777 PF05606.11 EMG50913.1 - 0.023 14.4 1.9 0.033 13.9 1.4 1.4 1 1 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) RisS_PPD PF16524.5 EMG50913.1 - 0.45 10.8 3.0 0.72 10.1 0.6 2.2 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS ALAD PF00490.21 EMG50914.1 - 2e-118 395.2 0.0 2.4e-118 394.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase HP1451_C PF18472.1 EMG50914.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 HP1451 C-terminal domain PQ-loop PF04193.14 EMG50915.1 - 7e-14 51.3 4.5 3.7e-09 36.2 0.1 3.6 2 1 0 2 2 2 2 PQ loop repeat DUF2955 PF11168.8 EMG50915.1 - 0.041 13.7 0.8 0.67 9.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) Pkinase PF00069.25 EMG50916.1 - 8.3e-69 231.9 0.0 1.2e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG50916.1 - 2.7e-31 108.8 0.0 4.4e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMG50916.1 - 2e-05 23.7 0.1 2.9e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EMG50916.1 - 7.7e-05 22.1 0.1 0.00046 19.6 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMG50916.1 - 0.00058 19.3 0.0 0.0077 15.6 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EMG50916.1 - 0.0014 18.6 0.1 0.0037 17.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EMG50916.1 - 0.02 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EMG50916.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Dus PF01207.17 EMG50917.1 - 4.7e-48 163.9 0.0 4.2e-47 160.8 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 EMG50917.1 - 0.27 11.1 3.3 2.6 7.9 0.4 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger Vps39_1 PF10366.9 EMG50920.1 - 1.6e-29 102.4 5.4 3.9e-29 101.1 0.8 3.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EMG50920.1 - 2.4e-15 56.9 0.1 7.6e-15 55.3 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EMG50920.1 - 3.3e-05 23.7 0.3 7.8e-05 22.4 0.3 1.6 1 0 0 1 1 1 1 CNH domain BBS2_N PF14781.6 EMG50920.1 - 0.96 9.4 3.5 5.1 7.0 0.1 3.4 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal Utp21 PF04192.12 EMG50921.1 - 2.9e-73 246.2 2.7 4.8e-73 245.5 2.7 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EMG50921.1 - 1.8e-14 53.8 0.2 0.00019 21.7 0.0 5.7 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMG50921.1 - 1e-09 38.8 17.0 1.4e-06 28.9 0.2 8.2 10 0 0 10 10 10 1 WD domain, G-beta repeat PQQ_2 PF13360.6 EMG50921.1 - 1.2e-05 25.0 0.0 8.2e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.16 EMG50921.1 - 0.0046 15.5 0.0 0.016 13.8 0.0 1.8 2 0 0 2 2 2 1 Cytochrome D1 heme domain Hira PF07569.11 EMG50921.1 - 0.029 14.1 0.0 0.13 12.0 0.0 2.1 1 0 0 1 1 1 0 TUP1-like enhancer of split PQQ PF01011.21 EMG50921.1 - 0.13 12.3 0.6 13 5.9 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat Csm2_III-A PF03750.13 EMG50921.1 - 0.55 11.1 2.1 26 5.7 0.3 3.0 3 0 0 3 3 3 0 Csm2 Type III-A Nrap_D5 PF17406.2 EMG50922.1 - 6.2e-52 175.6 0.8 1.5e-51 174.4 0.0 2.1 3 0 0 3 3 3 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 EMG50922.1 - 1.3e-51 174.4 3.8 4.4e-50 169.4 0.6 3.0 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 EMG50922.1 - 5.2e-51 173.0 0.3 5.2e-51 173.0 0.3 1.9 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 EMG50922.1 - 6.7e-47 159.5 0.0 1.8e-46 158.1 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 EMG50922.1 - 1.4e-45 155.1 8.0 3.8e-45 153.6 5.5 2.8 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D6 PF17407.2 EMG50922.1 - 1.7e-28 99.5 0.1 1.7e-28 99.5 0.1 2.3 2 0 0 2 2 2 1 Nrap protein domain 6 GCIP PF13324.6 EMG50922.1 - 0.13 11.8 12.6 0.11 12.1 8.5 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting RNA_pol_Rbc25 PF08292.12 EMG50922.1 - 7.1 6.9 6.8 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 SQHop_cyclase_C PF13243.6 EMG50923.1 - 3.8e-41 141.2 0.3 1.6e-39 135.9 0.1 2.3 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EMG50923.1 - 2.2e-36 125.5 0.0 1.9e-31 109.3 0.0 3.7 2 1 2 4 4 4 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EMG50923.1 - 6e-26 89.9 7.7 4.1e-08 32.8 0.3 4.5 4 1 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EMG50923.1 - 0.0002 20.8 1.2 1.2 8.4 0.0 5.0 4 2 2 6 6 6 1 Pectic acid lyase TED_complement PF07678.14 EMG50923.1 - 0.01 14.9 0.1 0.21 10.6 0.0 2.5 2 1 1 3 3 3 0 A-macroglobulin TED domain Gpr1_Fun34_YaaH PF01184.19 EMG50924.1 - 8.1e-57 192.2 28.1 9.9e-57 191.9 28.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BRAP2 PF07576.12 EMG50925.1 - 1.1e-32 112.2 0.1 2.3e-32 111.2 0.1 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EMG50925.1 - 1.2e-19 70.3 3.6 2.8e-19 69.2 3.6 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EMG50925.1 - 3.8e-08 33.5 10.4 3.8e-08 33.5 10.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMG50925.1 - 2.6e-06 27.2 11.4 6.9e-06 25.8 11.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG50925.1 - 8.3e-06 25.7 6.9 6.4e-05 22.9 7.2 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 EMG50925.1 - 3.9e-05 23.3 4.4 3.9e-05 23.3 4.4 2.1 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EMG50925.1 - 5e-05 23.1 10.0 0.00016 21.5 10.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMG50925.1 - 0.00021 21.5 8.0 0.00021 21.5 8.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EMG50925.1 - 0.00031 20.5 7.7 0.00031 20.5 7.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMG50925.1 - 0.00051 19.9 8.2 0.00051 19.9 8.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain CEP209_CC5 PF16574.5 EMG50925.1 - 0.007 16.5 9.5 0.007 16.5 9.5 2.0 2 0 0 2 2 2 1 Coiled-coil region of centrosome protein CE290 zf-ANAPC11 PF12861.7 EMG50925.1 - 0.0075 16.3 5.4 0.019 15.0 5.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SlyX PF04102.12 EMG50925.1 - 0.034 14.8 0.7 0.034 14.8 0.7 4.1 3 2 0 4 4 4 0 SlyX zf-RING_4 PF14570.6 EMG50925.1 - 0.67 9.8 14.9 0.022 14.5 7.9 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TMF_DNA_bd PF12329.8 EMG50925.1 - 2.5 8.2 32.0 0.2 11.7 6.5 3.9 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Prok-RING_4 PF14447.6 EMG50925.1 - 8 6.4 22.9 0.74 9.7 11.9 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Pribosyl_synth PF14572.6 EMG50926.1 - 2.6e-42 144.9 2.5 3.8e-36 124.8 1.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EMG50926.1 - 4.6e-39 133.0 0.3 1.5e-38 131.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EMG50926.1 - 1.4e-16 60.4 1.0 2.6e-16 59.5 1.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMG50926.1 - 0.014 14.8 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ISPD_C PF18706.1 EMG50926.1 - 0.084 12.5 0.8 0.14 11.8 0.8 1.3 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain TAFII55_N PF04658.13 EMG50927.1 - 1e-37 129.4 0.2 1e-37 129.4 0.2 3.7 3 1 1 4 4 4 1 TAFII55 protein conserved region P5-ATPase PF12409.8 EMG50928.1 - 1.6e-33 115.4 0.5 1.6e-33 115.4 0.5 2.3 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 EMG50928.1 - 7.7e-31 107.0 0.0 2e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EMG50928.1 - 1.1e-11 45.4 0.3 0.00011 22.6 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMG50928.1 - 1.3e-05 24.8 0.0 3.9e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EMG50928.1 - 1.4e-05 25.1 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 EMG50928.1 - 4.1e-05 23.4 9.5 4.1e-05 23.4 9.5 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 EMG50928.1 - 0.0023 17.7 0.2 1.9 8.2 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2015 PF09435.10 EMG50928.1 - 0.089 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) GATA PF00320.27 EMG50929.1 - 4.8e-14 51.7 5.4 1.1e-13 50.5 5.4 1.6 1 0 0 1 1 1 1 GATA zinc finger S1 PF00575.23 EMG50930.1 - 6.4e-54 180.2 44.5 5.5e-14 52.3 0.5 13.6 13 0 0 13 13 13 9 S1 RNA binding domain Suf PF05843.14 EMG50930.1 - 2.5e-05 24.4 2.8 2.5e-05 24.4 2.8 4.4 2 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EMG50930.1 - 0.00024 21.6 0.0 2.3 8.8 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat BUD22 PF09073.10 EMG50930.1 - 0.0035 16.8 57.6 0.14 11.4 15.1 2.3 2 0 0 2 2 2 2 BUD22 TPR_14 PF13428.6 EMG50930.1 - 0.0074 17.0 0.0 22 6.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 EMG50930.1 - 0.032 14.5 0.2 0.79 10.1 0.3 2.9 3 0 0 3 3 3 0 PPR repeat ProQ_C PF17516.2 EMG50930.1 - 0.039 13.4 3.3 0.73 9.3 0.3 4.6 5 0 0 5 5 5 0 ProQ C-terminal domain S1_2 PF13509.6 EMG50930.1 - 0.05 13.7 0.4 33 4.7 0.0 4.9 5 0 0 5 5 5 0 S1 domain ALS_ss_C PF10369.9 EMG50930.1 - 0.12 12.6 0.2 10 6.4 0.1 3.6 2 0 0 2 2 2 0 Small subunit of acetolactate synthase Ras_bdg_2 PF14847.6 EMG50930.1 - 0.2 12.0 2.7 15 6.0 0.0 4.0 3 1 0 4 4 4 0 Ras-binding domain of Byr2 DUF678 PF05077.12 EMG50930.1 - 0.88 9.8 2.8 15 5.8 1.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF678) Globin PF00042.22 EMG50931.1 - 0.0061 17.1 0.1 0.01 16.4 0.1 1.4 1 0 0 1 1 1 1 Globin VWA_N PF08399.11 EMG50931.1 - 0.043 14.3 0.3 0.043 14.3 0.3 2.3 2 0 0 2 2 2 0 VWA N-terminal Prok-RING_4 PF14447.6 EMG50932.1 - 0.00048 19.9 3.5 0.055 13.3 0.5 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EMG50932.1 - 0.0041 17.0 2.2 0.0041 17.0 2.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMG50932.1 - 0.0061 16.6 0.2 0.017 15.1 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EMG50932.1 - 0.0086 15.9 2.6 0.0086 15.9 2.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMG50932.1 - 0.0092 15.8 1.3 0.034 14.0 0.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMG50932.1 - 0.023 14.5 1.4 0.035 14.0 0.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMG50932.1 - 0.047 13.9 0.2 0.15 12.2 0.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING IBR PF01485.21 EMG50932.1 - 2.6 8.3 12.1 2.5 8.4 5.6 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EMG50932.1 - 2.7 8.4 8.1 0.46 10.9 2.5 2.5 3 0 0 3 3 3 0 Ring finger domain DUF4407 PF14362.6 EMG50932.1 - 3.3 7.0 10.9 1.6 8.0 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FYVE PF01363.21 EMG50932.1 - 6.5 7.0 8.0 2.1 8.6 4.1 2.2 2 1 0 2 2 2 0 FYVE zinc finger Opi1 PF08618.10 EMG50933.1 - 1e-16 61.2 15.1 9.1e-09 35.1 0.3 4.0 1 1 2 4 4 4 3 Transcription factor Opi1 Cation_efflux PF01545.21 EMG50934.1 - 1.7e-55 187.8 2.6 2.3e-55 187.4 2.6 1.2 1 0 0 1 1 1 1 Cation efflux family SNARE PF05739.19 EMG50935.1 - 2.6e-12 46.6 0.2 6.2e-12 45.3 0.2 1.7 1 0 0 1 1 1 1 SNARE domain DUF4999 PF16390.5 EMG50935.1 - 0.044 14.0 0.8 0.14 12.4 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function Syntaxin PF00804.25 EMG50935.1 - 0.078 12.6 11.2 0.13 11.9 6.9 2.7 2 1 0 2 2 2 0 Syntaxin FAM176 PF14851.6 EMG50935.1 - 0.081 12.6 2.1 0.53 9.9 1.2 2.4 3 0 0 3 3 3 0 FAM176 family MRAP PF15183.6 EMG50935.1 - 0.083 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family AI-2E_transport PF01594.16 EMG50935.1 - 2.9 6.9 4.1 5.3 6.1 0.2 2.4 2 1 1 3 3 3 0 AI-2E family transporter Septin PF00735.18 EMG50937.1 - 3.3e-76 256.2 2.1 5.9e-76 255.4 2.1 1.4 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 EMG50937.1 - 0.0049 16.9 2.7 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EMG50937.1 - 0.0052 16.9 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF29 PF01724.16 EMG50937.1 - 0.013 15.8 0.9 0.029 14.6 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF29 Ribosom_S12_S23 PF00164.25 EMG50937.1 - 0.017 14.7 0.2 0.033 13.8 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S12/S23 FeoB_N PF02421.18 EMG50937.1 - 0.023 14.2 0.1 0.058 12.9 0.1 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B Spore_III_AF PF09581.10 EMG50937.1 - 0.024 14.7 0.8 0.024 14.7 0.8 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) AKNA PF12443.8 EMG50937.1 - 0.032 14.9 1.5 0.058 14.0 0.3 2.2 2 0 0 2 2 1 0 AT-hook-containing transcription factor PduV-EutP PF10662.9 EMG50937.1 - 0.061 13.1 0.2 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Exonuc_VII_L PF02601.15 EMG50937.1 - 0.13 11.8 2.0 0.22 11.1 2.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EMG50937.1 - 0.15 11.4 2.1 0.23 10.8 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nsp1_C PF05064.13 EMG50937.1 - 0.18 11.6 7.1 0.2 11.5 3.5 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF3589 PF12141.8 EMG50938.1 - 4.9e-11 41.9 0.0 5.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Beta-mannosyltransferases CPG4 PF15481.6 EMG50938.1 - 0.032 14.8 0.2 0.052 14.2 0.2 1.3 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 Zip PF02535.22 EMG50939.1 - 4.2e-27 95.2 10.7 2.7e-18 66.3 6.3 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter BmKX PF09132.10 EMG50939.1 - 0.085 12.9 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 BmKX Vac7 PF12751.7 EMG50939.1 - 0.12 11.8 6.5 0.84 9.0 6.4 2.0 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 DUF2946 PF11162.8 EMG50939.1 - 0.46 11.2 0.1 0.46 11.2 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2946) DUF3784 PF12650.7 EMG50939.1 - 3 8.1 8.9 0.26 11.5 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) PNRC PF15365.6 EMG50940.1 - 1.4e-06 27.9 3.0 1.4e-06 27.9 3.0 2.2 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif PIN_4 PF13638.6 EMG50941.1 - 9.7e-07 29.1 0.0 6.4e-05 23.2 0.0 2.3 2 1 0 2 2 2 2 PIN domain SNF2_N PF00176.23 EMG50942.1 - 2.6e-71 240.2 0.9 2.6e-71 240.2 0.9 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EMG50942.1 - 2.3e-19 69.2 0.8 7.6e-19 67.6 0.8 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 EMG50942.1 - 1.6e-18 67.1 0.0 1.6e-18 67.1 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.6 EMG50942.1 - 2.2e-14 53.8 4.8 2.2e-14 53.8 4.8 3.5 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 EMG50942.1 - 9.8e-10 38.7 0.1 9.8e-10 38.7 0.1 3.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HSA PF07529.13 EMG50942.1 - 1.8e-08 34.6 7.4 1.8e-08 34.6 7.4 4.7 6 0 0 6 6 6 1 HSA Tristanin_u2 PF16638.5 EMG50942.1 - 4.2e-05 24.4 1.7 4.2e-05 24.4 1.7 7.0 8 0 0 8 8 8 1 Unstructured region on methyltransferase between zinc-fingers DUF5320 PF17253.2 EMG50942.1 - 0.035 15.2 0.1 0.035 15.2 0.1 6.1 6 0 0 6 6 6 0 Family of unknown function (DUF5320) RrnaAD PF00398.20 EMG50943.1 - 1.5e-27 96.3 0.0 1.9e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GidB PF02527.15 EMG50943.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Suf PF05843.14 EMG50945.1 - 7.5e-67 226.4 25.5 4.8e-65 220.5 11.4 4.9 3 3 0 3 3 3 2 Suppressor of forked protein (Suf) DUF4611 PF15387.6 EMG50945.1 - 0.0091 16.2 4.6 0.0091 16.2 4.6 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4611) TPR_19 PF14559.6 EMG50945.1 - 0.03 14.8 0.1 0.11 13.1 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Tom37 PF10568.9 EMG50946.1 - 1.8e-16 60.6 4.0 5.4e-16 59.0 4.0 1.8 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.8 EMG50946.1 - 1.8e-06 28.0 0.1 3.3e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Tom37 C-terminal domain ASTN_2_hairpin PF18577.1 EMG50946.1 - 0.14 12.3 0.0 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Astrotactin-2 C-terminal beta-hairpin domain DUF4448 PF14610.6 EMG50947.1 - 3.5e-62 209.6 0.2 3.5e-62 209.6 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) DUF4300 PF14133.6 EMG50947.1 - 0.015 15.0 1.0 0.036 13.7 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4300) Gpr1_Fun34_YaaH PF01184.19 EMG50948.1 - 4.3e-65 219.2 23.4 5.4e-65 218.9 23.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF423 PF04241.15 EMG50948.1 - 0.021 15.0 6.3 1.1 9.5 0.9 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF423) DAHP_synth_1 PF00793.20 EMG50949.1 - 1.6e-104 348.7 0.0 1.8e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF3597 PF12200.8 EMG50950.1 - 1.6 9.2 15.9 0.34 11.5 1.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3597) Musclin PF11037.8 EMG50950.1 - 9.3 6.2 9.2 11 5.9 1.3 3.2 1 1 1 2 2 2 0 Insulin-resistance promoting peptide in skeletal muscle UCH PF00443.29 EMG50952.1 - 1.2e-44 152.8 0.1 2.3e-44 151.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EMG50952.1 - 1e-20 73.8 6.9 3e-20 72.3 6.9 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EMG50952.1 - 2.3e-19 68.9 0.1 1.4e-10 40.9 0.0 3.1 3 0 0 3 3 3 2 UBA/TS-N domain zf-UBP_var PF17807.1 EMG50952.1 - 9.4e-19 66.9 0.5 3.2e-16 58.8 0.0 2.7 2 0 0 2 2 2 2 Variant UBP zinc finger UCH_1 PF13423.6 EMG50952.1 - 8.7e-14 51.8 0.3 6.1e-12 45.8 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase GGACT PF06094.12 EMG50952.1 - 0.18 12.4 1.2 3.5 8.3 0.0 3.3 4 0 0 4 4 4 0 Gamma-glutamyl cyclotransferase, AIG2-like SUR7 PF06687.12 EMG50954.1 - 1.4e-13 51.0 24.4 3.3e-13 49.8 24.4 1.6 1 0 0 1 1 1 1 SUR7/PalI family Wzy_C PF04932.15 EMG50954.1 - 0.091 12.4 4.6 0.065 12.9 1.0 2.6 2 1 0 2 2 2 0 O-Antigen ligase PIP5K PF01504.18 EMG50955.1 - 9.6e-41 139.8 8.1 1.8e-34 119.3 5.3 4.8 4 1 1 5 5 5 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EMG50955.1 - 1.8e-23 82.9 0.2 3.2e-23 82.1 0.2 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EMG50955.1 - 1.5e-16 60.2 8.8 1.5e-16 60.2 8.8 2.5 2 0 0 2 2 2 1 FYVE zinc finger GPP34 PF05719.11 EMG50956.1 - 7e-65 218.9 0.0 8.5e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Glyco_hydro_18 PF00704.28 EMG50957.1 - 1.3e-75 255.0 1.1 1.5e-75 254.8 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LRR_4 PF12799.7 EMG50958.1 - 0.0075 16.7 6.0 3.3 8.3 0.3 4.5 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) Leader_CPA1 PF08252.11 EMG50958.1 - 0.064 12.7 0.9 0.17 11.3 0.9 1.7 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide PLA2_B PF01735.18 EMG50959.1 - 2.4e-163 544.1 17.6 1.2e-162 541.7 17.6 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 EMG50959.1 - 0.084 13.1 1.7 0.27 11.5 1.7 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Pox_L3_FP4 PF03339.14 EMG50959.1 - 0.12 11.4 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein Androgen_recep PF02166.16 EMG50960.1 - 0.23 10.3 5.4 0.32 9.8 5.4 1.1 1 0 0 1 1 1 0 Androgen receptor Arrestin_C PF02752.22 EMG50961.1 - 4.5e-20 72.5 0.1 4e-19 69.4 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EMG50961.1 - 7.4e-07 29.3 0.0 0.00076 19.6 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Cyclin_N PF00134.23 EMG50962.1 - 1.1e-42 144.8 0.5 1.7e-40 137.7 0.2 2.7 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EMG50962.1 - 6.3e-31 106.9 0.8 1.8e-30 105.5 0.0 2.2 3 0 0 3 3 3 1 Cyclin, C-terminal domain TFIIA PF03153.13 EMG50962.1 - 1.3 8.9 14.7 1.6 8.6 14.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3439 PF11921.8 EMG50962.1 - 1.8 8.5 8.4 3.6 7.6 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RTT107_BRCT_5 PF16770.5 EMG50963.1 - 3.4e-28 97.5 8.8 1.8e-26 91.9 0.9 4.5 5 0 0 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 EMG50963.1 - 5.8e-26 90.7 10.3 1.7e-07 31.5 0.0 7.0 6 2 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EMG50963.1 - 3.1e-25 88.4 5.7 1.1e-05 25.7 0.0 6.3 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EMG50963.1 - 1.2e-20 73.2 3.7 8.9e-14 51.2 0.3 5.2 5 1 0 5 5 5 2 twin BRCT domain RTT107_BRCT_6 PF16771.5 EMG50963.1 - 6e-19 68.3 2.7 6e-19 68.3 2.7 2.3 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 EMG50963.1 - 1.7e-06 28.3 0.1 0.12 12.7 0.0 3.2 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EMG50963.1 - 0.00016 21.7 0.1 3.4 7.8 0.0 4.4 5 0 0 5 5 5 1 BRCA1 C Terminus (BRCT) domain UMP1 PF05348.11 EMG50963.1 - 0.078 13.2 0.6 0.21 11.8 0.1 1.9 2 0 0 2 2 2 0 Proteasome maturation factor UMP1 ENTH PF01417.20 EMG50964.1 - 2.8e-43 146.9 0.1 5.1e-43 146.1 0.1 1.5 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 EMG50964.1 - 8.9e-05 22.1 4.3 0.098 12.6 0.6 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif VHS PF00790.19 EMG50964.1 - 0.057 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 VHS domain HD PF01966.22 EMG50965.1 - 9.5e-06 25.8 0.0 1.4e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 HD domain Pribosyltran PF00156.27 EMG50966.1 - 8e-14 51.5 0.0 1.1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMG50966.1 - 0.061 12.8 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase bZIP_1 PF00170.21 EMG50967.1 - 0.0032 17.5 3.2 0.0032 17.5 3.2 3.9 2 1 2 4 4 4 1 bZIP transcription factor TSC22 PF01166.18 EMG50967.1 - 0.045 14.1 0.6 0.045 14.1 0.6 3.2 3 1 0 3 3 3 0 TSC-22/dip/bun family DivIC PF04977.15 EMG50967.1 - 0.051 13.3 15.9 0.048 13.4 2.3 3.4 3 1 0 3 3 3 0 Septum formation initiator DUF1664 PF07889.12 EMG50967.1 - 0.077 13.0 5.4 0.15 12.1 4.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 EMG50967.1 - 1.3 8.5 7.6 0.51 9.9 1.4 2.4 1 1 1 2 2 2 0 fzo-like conserved region Tho2 PF11262.8 EMG50967.1 - 2.3 7.3 14.7 0.32 10.1 5.3 2.8 1 1 2 3 3 3 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 EMG50967.1 - 2.5 7.4 8.1 6.1 6.1 8.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 EMG50967.1 - 4.1 7.9 20.4 2 8.9 3.7 3.2 2 1 1 3 3 3 0 Centromere protein H (CENP-H) YabA PF06156.13 EMG50967.1 - 4.9 7.8 17.0 0.28 11.8 6.2 3.2 1 1 2 3 3 3 0 Initiation control protein YabA ADIP PF11559.8 EMG50967.1 - 6.2 6.9 24.5 0.027 14.5 3.7 3.3 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding WD40 PF00400.32 EMG50969.1 - 3.7e-14 52.9 1.7 0.0019 19.0 0.2 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG50969.1 - 0.00019 21.6 0.1 2.8 8.3 0.0 4.6 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 EMG50969.1 - 0.079 11.2 13.4 0.11 10.7 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family eIF2A PF08662.11 EMG50969.1 - 0.12 12.3 1.5 2.1 8.2 0.3 3.1 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Pox_Ag35 PF03286.14 EMG50969.1 - 0.48 10.2 5.8 0.85 9.4 5.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 EMG50969.1 - 0.92 7.7 8.4 1.3 7.2 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EMG50969.1 - 3.7 6.8 14.1 6.4 6.0 14.1 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EMG50969.1 - 7.2 4.6 15.6 10 4.1 15.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ssl1 PF04056.14 EMG50970.1 - 3.1e-63 213.1 0.0 4.5e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EMG50970.1 - 9.6e-24 83.4 14.0 1.1e-22 80.0 8.4 2.6 2 0 0 2 2 2 2 TFIIH C1-like domain VWA_2 PF13519.6 EMG50970.1 - 2.3e-13 50.7 0.0 6.1e-13 49.3 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EMG50970.1 - 1.9e-06 28.2 0.1 3.2e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.7 EMG50970.1 - 0.00045 20.2 13.5 0.0096 15.9 0.3 3.0 2 1 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.6 EMG50970.1 - 0.0067 15.8 2.1 0.0067 15.8 2.1 3.0 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EMG50970.1 - 0.016 15.9 12.2 0.16 12.7 0.3 2.8 2 1 0 2 2 2 0 zinc-ribbon family zinc_ribbon_10 PF10058.9 EMG50970.1 - 0.039 13.7 3.3 4.2 7.2 0.1 3.4 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Anillin_N PF16018.5 EMG50970.1 - 0.052 14.1 0.4 0.12 13.0 0.4 1.7 1 0 0 1 1 1 0 Anillin N-terminus TackOD1 PF18551.1 EMG50970.1 - 0.23 11.1 0.1 0.23 11.1 0.1 2.8 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 Zn_ribbon_SprT PF17283.2 EMG50970.1 - 1.2 9.1 18.3 0.21 11.5 3.1 3.7 3 1 0 3 3 3 0 SprT-like zinc ribbon domain IBR PF01485.21 EMG50970.1 - 3.2 8.0 20.8 86 3.5 20.8 2.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 EMG50970.1 - 3.2 8.0 15.5 4 7.7 6.3 2.7 2 0 0 2 2 2 0 AN1-like Zinc finger CpXC PF14353.6 EMG50970.1 - 4.9 7.2 9.6 19 5.4 0.3 3.1 2 1 1 3 3 3 0 CpXC protein Spt5-NGN PF03439.13 EMG50971.1 - 2.1e-23 82.0 0.0 4.7e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EMG50971.1 - 3.5e-23 82.5 16.4 3.5e-23 82.5 16.4 3.4 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EMG50971.1 - 2.8e-14 52.5 9.9 5.5e-06 26.2 1.9 5.0 5 0 0 5 5 5 3 KOW motif NusG PF02357.19 EMG50971.1 - 0.016 15.7 0.8 2.8 8.5 0.0 3.0 2 1 0 2 2 2 0 Transcription termination factor nusG BUD22 PF09073.10 EMG50971.1 - 1.4 8.2 36.5 2.7 7.3 36.5 1.4 1 0 0 1 1 1 0 BUD22 Med13_N PF11597.8 EMG50972.1 - 2.9e-70 237.1 2.6 8e-70 235.7 2.6 1.8 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 EMG50972.1 - 1.1e-11 44.6 1.9 5.1e-07 29.3 0.1 5.3 4 2 1 5 5 5 2 Mediator complex subunit 13 C-terminal domain COX6A PF02046.15 EMG50973.1 - 6e-43 145.9 3.1 6.7e-43 145.7 3.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RNase_T PF00929.24 EMG50974.1 - 8.4e-32 111.0 0.0 1.2e-31 110.5 0.0 1.2 1 0 0 1 1 1 1 Exonuclease MinE PF03776.14 EMG50974.1 - 0.061 13.3 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Tn7_Tnp_TnsA_C PF08721.11 EMG50974.1 - 0.16 12.7 1.1 5 7.8 0.1 3.0 3 0 0 3 3 3 0 TnsA endonuclease C terminal DUF3589 PF12141.8 EMG50975.1 - 1.4e-173 578.1 1.7 1.6e-173 577.8 1.7 1.0 1 0 0 1 1 1 1 Beta-mannosyltransferases DUF3589 PF12141.8 EMG50976.1 - 4.2e-189 629.2 15.3 4.9e-189 629.0 15.3 1.0 1 0 0 1 1 1 1 Beta-mannosyltransferases DUF4895 PF16236.5 EMG50976.1 - 0.023 14.5 3.0 0.11 12.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4895) LNS2 PF08235.13 EMG50977.1 - 3.1e-94 314.7 0.0 5.1e-94 314.0 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EMG50977.1 - 6.8e-39 132.0 0.0 1.6e-38 130.8 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region TauD PF02668.16 EMG50977.1 - 5.8e-35 121.4 0.0 2.5e-34 119.3 0.0 1.9 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Hydrolase_6 PF13344.6 EMG50977.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CN_hydrolase PF00795.22 EMG50978.1 - 3.9e-44 150.9 0.0 5.4e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EMG50978.1 - 7.6e-22 77.6 0.0 2.3e-21 76.1 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Hydrolase_4 PF12146.8 EMG50979.1 - 3.8e-18 65.6 0.0 5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMG50979.1 - 2.2e-17 63.6 0.1 4.6e-17 62.5 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMG50979.1 - 1.6e-15 58.3 0.0 2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EMG50979.1 - 0.00032 20.5 0.0 0.00054 19.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EMG50979.1 - 0.00064 19.6 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EMG50979.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EMG50979.1 - 0.0046 17.1 0.0 0.0087 16.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 EMG50979.1 - 0.014 15.3 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Chlorophyllase2 PF12740.7 EMG50979.1 - 0.021 13.8 0.1 0.037 12.9 0.1 1.3 1 1 0 1 1 1 0 Chlorophyllase enzyme Ndr PF03096.14 EMG50979.1 - 0.033 12.9 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family LIDHydrolase PF10230.9 EMG50979.1 - 0.038 13.6 0.1 0.051 13.1 0.1 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Exonuc_VIII PF06630.11 EMG50979.1 - 0.059 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII Abhydrolase_3 PF07859.13 EMG50979.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EMG50979.1 - 0.099 12.2 0.0 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF915 PF06028.11 EMG50979.1 - 0.12 11.7 0.0 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) EF-hand_7 PF13499.6 EMG50980.1 - 0.00016 22.0 0.2 0.034 14.6 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair COX5B PF01215.19 EMG50981.1 - 7.4e-55 184.1 0.2 8.7e-55 183.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Ribosomal_S26e PF01283.19 EMG50982.1 - 1.5e-52 176.6 10.2 1.8e-52 176.3 10.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e FYVE PF01363.21 EMG50983.1 - 3.3e-15 56.0 5.1 7.7e-15 54.8 5.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 EMG50983.1 - 0.13 12.5 8.9 0.31 11.2 8.9 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger STT3 PF02516.14 EMG50984.1 - 4.9e-158 527.1 43.5 2.4e-154 514.9 40.5 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 EMG50984.1 - 0.001 19.3 12.0 0.001 19.3 12.0 3.1 3 2 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MT-A70 PF05063.14 EMG50985.1 - 4.5e-53 179.7 1.0 9.9e-53 178.6 0.2 1.8 2 0 0 2 2 2 1 MT-A70 SH3_1 PF00018.28 EMG50986.1 - 1.1e-35 121.0 12.8 8e-14 51.0 0.4 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 EMG50986.1 - 2.1e-33 114.0 7.3 7.9e-11 41.6 0.1 4.3 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 EMG50986.1 - 2.2e-32 110.7 0.0 4e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 EMG50986.1 - 5.8e-24 83.5 0.3 8.1e-08 31.8 0.1 4.8 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 EMG50986.1 - 0.00036 20.4 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Spc24 PF08286.11 EMG50987.1 - 5.6e-23 81.2 7.4 5.3e-22 78.0 2.2 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.6 EMG50987.1 - 5.2e-05 23.6 11.0 0.0018 18.7 0.8 3.1 2 1 1 3 3 3 2 Snapin/Pallidin DUF4618 PF15397.6 EMG50987.1 - 0.0018 17.8 9.9 0.0045 16.4 9.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) Lipoprotein_20 PF13942.6 EMG50987.1 - 0.013 15.5 9.4 0.031 14.2 1.0 2.2 2 0 0 2 2 2 0 YfhG lipoprotein Rootletin PF15035.6 EMG50987.1 - 0.026 14.6 4.5 0.039 14.0 4.5 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3552 PF12072.8 EMG50987.1 - 0.029 13.8 6.6 0.079 12.4 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) SlyX PF04102.12 EMG50987.1 - 0.35 11.5 8.4 0.56 10.9 1.0 2.7 2 0 0 2 2 2 0 SlyX JMY PF15871.5 EMG50987.1 - 0.56 9.5 8.8 0.12 11.6 3.5 1.9 1 1 1 2 2 2 0 Junction-mediating and -regulatory protein DUF4795 PF16043.5 EMG50987.1 - 0.66 9.5 12.0 1.4 8.4 11.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF848 PF05852.11 EMG50987.1 - 0.79 9.8 7.7 0.23 11.5 0.7 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4200 PF13863.6 EMG50987.1 - 2.1 8.8 7.7 13 6.2 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin PF02996.17 EMG50987.1 - 2.4 8.1 8.8 7.3 6.5 1.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit EMP24_GP25L PF01105.24 EMG50987.1 - 2.5 8.0 10.8 3 7.7 2.1 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD TolA_bind_tri PF16331.5 EMG50987.1 - 3.1 8.0 10.0 10 6.3 2.8 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation BORCS7 PF16088.5 EMG50987.1 - 5.9 7.2 14.7 0.35 11.2 3.1 3.2 2 2 1 3 3 3 0 BLOC-1-related complex sub-unit 7 DUF2120 PF09893.9 EMG50987.1 - 7.3 6.7 9.7 1.1 9.4 2.1 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Fzo_mitofusin PF04799.13 EMG50987.1 - 8.2 5.9 8.1 3.8 7.0 1.2 2.1 1 1 0 2 2 2 0 fzo-like conserved region DUF1664 PF07889.12 EMG50987.1 - 9.5 6.3 11.3 3.3 7.8 2.6 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Cmc1 PF08583.10 EMG50988.1 - 1.2e-07 31.7 4.2 1.2e-07 31.7 4.2 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DcuA_DcuB PF03605.14 EMG50988.1 - 0.33 9.8 2.3 0.34 9.7 2.3 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DASH_Hsk3 PF08227.11 EMG50989.1 - 7.3e-15 55.1 0.9 1e-14 54.6 0.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like FlxA PF14282.6 EMG50989.1 - 0.016 15.2 0.2 0.02 14.9 0.2 1.1 1 0 0 1 1 1 0 FlxA-like protein ABC_tran_CTD PF16326.5 EMG50989.1 - 0.12 12.7 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 ABC transporter C-terminal domain Hap4_Hap_bind PF10297.9 EMG50990.1 - 4.2e-07 29.9 10.3 1.1e-06 28.5 10.3 1.8 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Tir_receptor_C PF07489.11 EMG50990.1 - 9 6.2 21.0 0.8 9.6 5.6 3.0 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) C-terminus Sdh_cyt PF01127.22 EMG50991.1 - 6.7e-28 97.2 1.3 8.4e-28 96.8 1.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ecl1 PF12855.7 EMG50992.1 - 4.2e-12 47.6 9.2 5e-12 47.3 9.2 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 EMG50992.1 - 0.041 14.0 5.7 0.041 14.0 5.7 2.4 2 0 0 2 2 2 0 MYND finger zf-C6H2 PF15801.5 EMG50992.1 - 0.068 13.5 6.4 0.068 13.5 6.4 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding CbtA PF09490.10 EMG50992.1 - 1 9.1 1.9 1.3 8.7 1.9 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) HSP70 PF00012.20 EMG50993.1 - 8.1e-260 863.1 14.3 9.3e-260 862.9 14.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMG50993.1 - 2.8e-19 69.1 1.8 1.8e-18 66.4 0.5 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EMG50993.1 - 0.00089 19.6 3.0 1.4 9.3 0.1 3.5 3 1 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 EMG50993.1 - 0.0092 15.0 1.1 0.026 13.5 1.0 1.8 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain DUF1464 PF07318.12 EMG50993.1 - 0.0096 15.1 0.1 0.75 8.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1464) Hydantoinase_A PF01968.18 EMG50993.1 - 0.16 11.2 3.8 0.47 9.7 0.2 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DIOX_N PF14226.6 EMG50993.1 - 0.16 12.7 0.5 1.1 10.1 0.2 2.3 1 1 1 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal cNMP_binding PF00027.29 EMG50994.1 - 4.4e-42 142.1 0.1 2.9e-20 72.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 EMG50994.1 - 1e-10 41.1 0.3 5.7e-10 38.7 0.1 2.3 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit Erg28 PF03694.13 EMG50995.1 - 6.8e-45 152.0 1.1 8.2e-45 151.7 1.1 1.1 1 0 0 1 1 1 1 Erg28 like protein Vps54 PF07928.12 EMG50996.1 - 7.3e-15 55.6 19.1 2.6e-14 53.8 8.5 4.9 4 1 0 4 4 4 1 Vps54-like protein Vps54_N PF10475.9 EMG50996.1 - 7e-09 35.4 7.8 1e-05 25.0 1.6 2.6 2 0 0 2 2 2 2 Vacuolar-sorting protein 54, of GARP complex DUF3216 PF11505.8 EMG50996.1 - 0.5 10.6 0.0 0.5 10.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3216) IF-2B PF01008.17 EMG50997.1 - 1.3e-47 162.3 0.1 3.2e-47 161.1 0.1 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Pex2_Pex12 PF04757.14 EMG50998.1 - 6.9e-56 189.4 15.6 1e-55 188.8 15.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EMG50998.1 - 0.0014 18.8 0.5 0.0027 17.8 0.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EMG50998.1 - 0.02 14.9 0.1 0.045 13.8 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EMG50998.1 - 0.04 13.8 0.2 0.093 12.6 0.1 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FAM176 PF14851.6 EMG50998.1 - 0.15 11.7 1.4 0.3 10.7 1.4 1.4 1 0 0 1 1 1 0 FAM176 family Saw1 PF11561.8 EMG50998.1 - 0.31 10.5 5.2 0.89 9.0 2.0 2.2 2 0 0 2 2 2 0 Single strand annealing-weakened 1 NOA36 PF06524.12 EMG50998.1 - 0.61 9.4 5.6 1.1 8.6 5.6 1.3 1 0 0 1 1 1 0 NOA36 protein Not3 PF04065.15 EMG50999.1 - 2.9e-67 226.5 28.6 6.8e-67 225.3 28.6 1.6 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component DUF2235 PF09994.9 EMG50999.1 - 0.025 13.9 1.4 0.07 12.5 1.4 1.7 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) CEP63 PF17045.5 EMG50999.1 - 1.7 8.4 19.9 1.6 8.6 4.0 2.4 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF2203 PF09969.9 EMG50999.1 - 4.5 8.0 8.1 3.4 8.4 1.3 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Arm-DNA-bind_2 PF12167.8 EMG50999.1 - 4.6 7.2 5.3 6.3 6.8 0.4 2.9 2 1 0 2 2 2 0 Arm DNA-binding domain DUF1752 PF08550.10 EMG51000.1 - 1.2e-12 47.4 3.3 2.5e-12 46.4 3.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) STIMATE PF12400.8 EMG51001.1 - 1.7e-37 128.7 8.5 1.7e-37 128.7 8.5 1.9 2 0 0 2 2 2 1 STIMATE family Pkinase PF00069.25 EMG51002.1 - 1.5e-41 142.5 0.4 4.4e-41 141.0 0.4 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG51002.1 - 5.1e-22 78.4 0.3 9.1e-17 61.2 0.2 2.9 1 1 0 2 2 2 2 Protein tyrosine kinase Choline_kinase PF01633.20 EMG51002.1 - 1.1e-05 25.1 0.5 1.1e-05 25.1 0.5 2.2 2 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EMG51002.1 - 3.7e-05 23.8 0.3 9.4e-05 22.4 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EMG51002.1 - 0.0015 18.2 1.3 0.0042 16.7 1.3 1.8 1 0 0 1 1 1 1 RIO1 family PLD_C PF12357.8 EMG51002.1 - 0.007 16.2 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Phospholipase D C terminal Kdo PF06293.14 EMG51002.1 - 0.095 12.0 5.2 0.054 12.8 2.8 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.28 EMG51003.1 - 1.2e-17 65.2 0.0 4.4e-17 63.3 0.0 2.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mpp10 PF04006.12 EMG51003.1 - 0.015 13.8 28.2 0.021 13.3 28.2 1.1 1 0 0 1 1 1 0 Mpp10 protein CAC1F_C PF16885.5 EMG51003.1 - 0.45 10.1 9.6 0.7 9.5 9.6 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term CDC45 PF02724.14 EMG51003.1 - 1.4 7.1 19.9 2 6.6 19.9 1.1 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 EMG51003.1 - 1.5 9.1 9.9 2.3 8.4 9.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.15 EMG51003.1 - 5.5 5.7 13.7 7.8 5.2 13.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 EMG51003.1 - 5.8 5.3 10.1 11 4.5 10.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.10 EMG51003.1 - 5.9 7.2 21.3 12 6.2 21.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 EMG51003.1 - 8 5.1 14.8 11 4.7 14.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 EMG51003.1 - 9.9 5.4 12.2 18 4.6 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 EMG51004.1 - 1.6e-63 214.5 0.0 2.5e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMG51004.1 - 6.6e-48 163.2 0.0 1e-47 162.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EMG51004.1 - 2.6e-37 127.2 0.1 6.1e-37 126.0 0.1 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 EMG51004.1 - 5.2e-09 36.4 0.1 1.4e-08 35.0 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EMG51004.1 - 1e-08 35.1 0.1 2.7e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 EMG51004.1 - 0.00017 21.0 0.0 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EMG51004.1 - 0.027 13.3 0.0 0.077 11.8 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase RA PF00788.23 EMG51004.1 - 0.061 14.0 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Glyco_hydro_52 PF03512.13 EMG51004.1 - 0.087 11.8 0.0 0.42 9.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 52 Bcr-Abl_Oligo PF09036.10 EMG51005.1 - 0.02 14.9 1.4 0.34 10.9 0.2 2.2 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Phage_B PF02304.15 EMG51005.1 - 0.053 13.9 0.5 12 6.4 0.1 2.2 1 1 1 2 2 2 0 Scaffold protein B Ferric_reduct PF01794.19 EMG51006.1 - 1.9e-18 66.8 6.9 1.9e-18 66.8 6.9 3.2 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMG51006.1 - 7e-08 32.7 0.0 6.5e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMG51006.1 - 2.8e-07 30.6 0.5 5.8e-07 29.6 0.5 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EMG51006.1 - 0.0085 16.7 0.0 0.031 14.9 0.0 1.9 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain DUF2070 PF09843.9 EMG51006.1 - 0.23 9.7 16.3 0.35 9.1 16.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2244 PF10003.9 EMG51006.1 - 0.53 10.0 8.6 0.046 13.4 2.8 2.2 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) HLH PF00010.26 EMG51007.1 - 5.7e-08 32.6 1.5 5.7e-08 32.6 1.5 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4662 PF15578.6 EMG51007.1 - 0.04 13.7 2.1 0.047 13.5 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) DUF3322 PF11795.8 EMG51007.1 - 0.067 13.2 0.1 0.08 12.9 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF5094 PF17015.5 EMG51007.1 - 0.26 11.4 5.1 0.33 11.0 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Diphthami_syn_2 PF01902.17 EMG51008.1 - 1.1e-39 136.2 0.0 2.2e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EMG51008.1 - 1.3e-18 67.2 0.0 3.1e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 Endoribonuclease L-PSP QueC PF06508.13 EMG51008.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC S4 PF01479.25 EMG51009.1 - 1.4e-12 47.1 0.7 5.1e-12 45.3 0.2 2.0 2 0 0 2 2 2 1 S4 domain Ribosomal_L21e PF01157.18 EMG51010.1 - 2.8e-46 155.5 6.7 5.5e-46 154.6 5.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 EMG51010.1 - 0.00053 19.6 0.0 0.00064 19.4 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 CASP_C PF08172.12 EMG51011.1 - 1.6e-75 253.7 5.0 1.6e-75 253.7 5.0 3.5 3 1 1 4 4 4 1 CASP C terminal DUF2935 PF11155.8 EMG51011.1 - 1.2e-08 35.3 7.8 0.039 14.3 0.1 5.5 3 2 1 4 4 4 2 Domain of unknown function (DUF2935) NPV_P10 PF05531.12 EMG51011.1 - 5.8e-05 23.5 1.1 5.8e-05 23.5 1.1 6.3 6 2 0 6 6 6 1 Nucleopolyhedrovirus P10 protein PglZ PF08665.12 EMG51011.1 - 0.012 15.8 0.2 0.012 15.8 0.2 3.4 3 1 1 4 4 4 0 PglZ domain Mto2_bdg PF12808.7 EMG51011.1 - 0.025 14.9 2.0 0.025 14.9 2.0 6.8 10 0 0 10 10 10 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF1154 PF06631.11 EMG51011.1 - 5 7.2 17.2 0.53 10.3 1.4 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1154) Ada_Zn_binding PF02805.16 EMG51013.1 - 1.9e-20 72.6 1.5 3.4e-20 71.8 1.5 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 EMG51013.1 - 0.00085 19.4 0.1 0.0026 17.8 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EMG51013.1 - 0.003 17.8 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain zf-FPG_IleRS PF06827.14 EMG51013.1 - 0.0044 16.8 1.5 0.005 16.7 0.0 1.9 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS CN_hydrolase PF00795.22 EMG51016.1 - 4.4e-21 75.4 0.0 3.4e-17 62.6 0.0 2.7 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase LicD PF04991.13 EMG51017.1 - 1.8e-26 93.7 3.5 1.8e-26 93.7 3.5 4.1 4 1 0 5 5 5 2 LicD family CaM-KIIN PF15170.6 EMG51017.1 - 0.13 12.5 0.1 0.32 11.2 0.1 1.7 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor DUF2990 PF11693.8 EMG51017.1 - 0.2 11.9 0.2 0.57 10.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) CHZ PF09649.10 EMG51017.1 - 5.1 6.7 7.2 1.1 8.8 1.8 2.4 2 0 0 2 2 2 0 Histone chaperone domain CHZ DUF3589 PF12141.8 EMG51018.1 - 1.9e-172 574.3 1.2 2.2e-172 574.1 1.2 1.0 1 0 0 1 1 1 1 Beta-mannosyltransferases FMO-like PF00743.19 EMG51019.1 - 4e-14 51.9 0.7 1e-10 40.7 0.3 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EMG51019.1 - 1.4e-10 40.9 0.1 1.7e-08 34.0 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMG51019.1 - 1.5e-09 37.6 0.0 2.3e-07 30.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMG51019.1 - 3.9e-09 36.2 0.0 1e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMG51019.1 - 1.9e-07 31.2 0.0 4.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMG51019.1 - 9.5e-05 22.4 0.0 0.0016 18.4 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EMG51019.1 - 0.0017 18.0 0.1 0.011 15.3 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EMG51019.1 - 0.04 14.0 0.0 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EMG51019.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EMG51019.1 - 0.11 11.7 0.0 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family FTR PF01913.18 EMG51019.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Aminotran_3 PF00202.21 EMG51021.1 - 1.1e-111 373.4 0.0 1.3e-111 373.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMG51021.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Longin_2 PF18639.1 EMG51022.1 - 5.4e-11 42.6 2.0 0.00043 20.2 0.3 3.7 4 0 0 4 4 4 2 Yeast longin domain FNIP_N PF14636.6 EMG51022.1 - 3.2e-05 25.0 1.0 3.2e-05 25.0 1.0 4.8 4 1 1 5 5 5 1 Folliculin-interacting protein N-terminus ADH_zinc_N_2 PF13602.6 EMG51024.1 - 4.7e-23 82.7 0.0 9.2e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMG51024.1 - 2.1e-09 37.4 0.0 4.4e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG51024.1 - 0.0041 17.0 0.0 0.014 15.3 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 EMG51024.1 - 0.033 13.3 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 EMG51024.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LicD PF04991.13 EMG51026.1 - 3.5e-29 102.6 25.8 6.8e-28 98.3 4.2 4.0 3 1 1 4 4 4 2 LicD family Organ_specific PF10950.8 EMG51026.1 - 0.12 13.1 1.5 7.9 7.2 0.1 2.8 2 1 0 2 2 2 0 Organ specific protein OEP PF02321.18 EMG51026.1 - 1.4 8.7 7.5 5.8 6.7 2.6 2.9 3 0 0 3 3 3 0 Outer membrane efflux protein Mgr1 PF08602.10 EMG51028.1 - 1.7e-22 79.8 5.0 1.7e-10 40.3 0.1 3.8 1 1 2 3 3 3 3 Mgr1-like, i-AAA protease complex subunit Inhibitor_I71 PF12628.7 EMG51028.1 - 1.5 8.6 4.3 8.3 6.2 0.1 2.5 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor SR-25 PF10500.9 EMG51028.1 - 2.3 7.8 10.4 4.4 6.8 10.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein COX5A PF02284.16 EMG51029.1 - 1.3e-37 127.9 1.0 1.8e-37 127.5 1.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va HHH_8 PF14716.6 EMG51029.1 - 0.093 13.1 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain bZIP_1 PF00170.21 EMG51031.1 - 1.8e-08 34.4 12.8 2.4e-06 27.6 4.7 2.2 1 1 1 2 2 2 2 bZIP transcription factor TMCO5 PF14992.6 EMG51031.1 - 0.0081 15.8 2.3 0.01 15.4 2.3 1.2 1 0 0 1 1 1 1 TMCO5 family DUF3450 PF11932.8 EMG51031.1 - 0.035 13.4 4.7 0.046 13.0 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2205 PF10224.9 EMG51031.1 - 0.059 13.4 0.9 0.096 12.7 0.9 1.3 1 0 0 1 1 1 0 Short coiled-coil protein HAUS6_N PF14661.6 EMG51031.1 - 0.14 11.7 4.7 0.17 11.4 4.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PRKG1_interact PF15898.5 EMG51031.1 - 0.16 12.9 6.9 0.18 12.8 6.1 1.5 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF1465 PF07323.12 EMG51031.1 - 0.21 11.5 3.3 0.31 10.9 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) bZIP_2 PF07716.15 EMG51031.1 - 0.74 9.9 14.4 31 4.7 14.4 2.2 1 1 0 1 1 1 0 Basic region leucine zipper PBP PF01161.20 EMG51032.1 - 1.2e-05 25.7 0.1 2.5e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF688 PF05097.12 EMG51032.1 - 0.0027 17.0 0.7 0.0027 17.0 0.7 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF688) NOA36 PF06524.12 EMG51032.1 - 1.5 8.1 9.7 2.2 7.5 9.7 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EMG51032.1 - 3.3 7.7 7.8 0.25 11.4 2.2 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 EMG51032.1 - 7.4 6.2 18.6 0.06 13.1 10.4 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Upf2 PF04050.14 EMG51033.1 - 7.5e-22 78.5 9.6 7.5e-22 78.5 9.6 3.1 2 1 1 3 3 3 1 Up-frameshift suppressor 2 MIF4G PF02854.19 EMG51033.1 - 2.6e-17 63.2 41.7 5.6e-11 42.5 2.8 4.7 4 2 0 4 4 4 3 MIF4G domain Nop14 PF04147.12 EMG51033.1 - 0.023 12.9 39.8 0.051 11.8 39.8 1.5 1 0 0 1 1 1 0 Nop14-like family Serglycin PF04360.12 EMG51033.1 - 0.61 10.0 6.4 0.62 10.0 0.3 3.1 2 1 1 3 3 3 0 Serglycin YL1 PF05764.13 EMG51033.1 - 0.97 9.5 35.7 3.2 7.8 35.7 1.9 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 EMG51033.1 - 1.3 8.4 45.2 0.021 14.3 37.7 1.8 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 EMG51033.1 - 1.5 7.0 34.2 0.24 9.6 29.9 1.7 2 0 0 2 2 2 0 CDC45-like protein BUD22 PF09073.10 EMG51033.1 - 5.3 6.3 46.2 2.6 7.3 37.8 2.5 2 0 0 2 2 2 0 BUD22 IMS PF00817.20 EMG51034.1 - 9.4e-43 145.8 0.0 1.6e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 EMG51034.1 - 1.8e-05 24.8 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif Sec23_trunk PF04811.15 EMG51035.1 - 4.6e-42 144.3 0.0 1.1e-41 143.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EMG51035.1 - 1.3e-18 66.7 0.1 3.3e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EMG51035.1 - 5.3e-18 65.5 0.0 5.3e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EMG51035.1 - 6.6e-12 45.3 8.2 1.6e-11 44.0 8.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger zinc_ribbon_9 PF14369.6 EMG51035.1 - 1.6 9.1 3.7 3.6 7.9 3.7 1.6 1 0 0 1 1 1 0 zinc-ribbon UNC45-central PF11701.8 EMG51036.1 - 2e-34 118.8 1.6 2e-34 118.8 1.6 2.4 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central Arm PF00514.23 EMG51036.1 - 4.1 7.6 7.7 1.1 9.4 0.9 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat ING PF12998.7 EMG51037.1 - 5.4e-15 55.8 4.6 8.7e-15 55.1 4.6 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EMG51037.1 - 1.8e-06 27.7 8.2 3.5e-06 26.8 8.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EMG51037.1 - 0.017 15.4 0.2 0.04 14.2 0.2 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 EMG51037.1 - 0.025 14.1 2.6 0.052 13.1 2.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-C4_Topoisom PF01396.19 EMG51037.1 - 0.92 9.3 6.1 3.2 7.6 0.8 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger PhnA_Zn_Ribbon PF08274.12 EMG51037.1 - 1.2 9.2 4.5 2.8 8.0 0.3 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon PalH PF08733.10 EMG51038.1 - 7.6e-65 219.1 20.7 1.2e-64 218.5 20.7 1.3 1 0 0 1 1 1 1 PalH/RIM21 GWT1 PF06423.12 EMG51038.1 - 0.78 9.9 8.1 2.1 8.4 4.5 2.6 2 0 0 2 2 2 0 GWT1 AAA_2 PF07724.14 EMG51039.1 - 8.7e-52 175.7 0.4 1.4e-50 171.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EMG51039.1 - 3.9e-33 113.5 1.2 3.9e-33 113.5 1.2 2.9 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EMG51039.1 - 1.1e-23 83.1 0.5 4.7e-23 81.0 0.5 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EMG51039.1 - 1.5e-20 74.0 0.2 1e-10 42.2 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMG51039.1 - 7.8e-16 58.3 0.0 4.5e-10 39.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMG51039.1 - 3.6e-10 40.5 4.7 0.00058 20.3 0.1 4.6 3 2 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 EMG51039.1 - 7.4e-09 36.0 0.9 0.00088 19.6 0.0 3.8 2 2 1 3 3 2 2 AAA domain Sigma54_activat PF00158.26 EMG51039.1 - 1.1e-08 35.0 0.1 1.4e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 EMG51039.1 - 3.7e-07 29.8 0.0 0.0035 16.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 EMG51039.1 - 5.5e-07 29.7 0.0 0.029 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EMG51039.1 - 1.2e-05 25.2 0.0 0.077 12.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 EMG51039.1 - 4.6e-05 23.7 0.3 1.6 8.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 EMG51039.1 - 6.3e-05 23.0 0.2 0.34 10.8 0.0 3.0 3 0 0 3 3 2 2 NACHT domain RNA_helicase PF00910.22 EMG51039.1 - 6.9e-05 23.2 0.5 0.28 11.6 0.0 3.5 3 1 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 EMG51039.1 - 0.00014 21.7 0.3 0.11 12.1 0.0 3.3 3 1 1 4 4 3 1 AAA domain ResIII PF04851.15 EMG51039.1 - 0.00019 21.5 0.4 1.1 9.3 0.0 3.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 EMG51039.1 - 0.0004 20.4 10.7 0.6 10.0 0.1 4.4 3 2 2 5 5 4 2 ATPase domain predominantly from Archaea AAA_6 PF12774.7 EMG51039.1 - 0.00048 19.2 0.0 0.024 13.6 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 EMG51039.1 - 0.00077 19.5 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 EMG51039.1 - 0.0013 17.7 0.4 0.56 9.1 0.2 2.7 2 1 1 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 EMG51039.1 - 0.0016 17.7 0.8 0.48 9.5 0.2 3.4 2 2 0 2 2 2 1 Protein of unknown function (DUF815) SRP54 PF00448.22 EMG51039.1 - 0.0026 17.4 0.1 0.44 10.2 0.0 3.0 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EMG51039.1 - 0.0033 16.7 2.0 0.17 11.1 0.0 3.6 4 0 0 4 4 4 1 Zeta toxin AAA_24 PF13479.6 EMG51039.1 - 0.004 16.9 0.1 0.76 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EMG51039.1 - 0.004 17.5 3.7 0.48 10.7 0.1 3.8 4 1 0 4 4 2 1 AAA domain PhoH PF02562.16 EMG51039.1 - 0.0042 16.6 0.0 3.5 7.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Roc PF08477.13 EMG51039.1 - 0.0051 17.0 0.1 2.2 8.5 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 EMG51039.1 - 0.0059 16.0 0.1 2 7.7 0.0 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EMG51039.1 - 0.0086 16.6 2.8 0.47 11.0 0.0 3.6 3 1 0 3 3 3 1 ABC transporter T2SSE PF00437.20 EMG51039.1 - 0.01 14.9 0.6 0.23 10.5 0.1 3.0 2 1 1 3 3 3 0 Type II/IV secretion system protein DUF87 PF01935.17 EMG51039.1 - 0.011 15.9 5.0 1.7 8.7 0.0 3.7 3 0 0 3 3 3 0 Helicase HerA, central domain PduV-EutP PF10662.9 EMG51039.1 - 0.011 15.5 0.2 0.75 9.5 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DUF853 PF05872.12 EMG51039.1 - 0.012 14.2 0.2 0.16 10.5 0.2 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_33 PF13671.6 EMG51039.1 - 0.014 15.6 0.1 4 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMG51039.1 - 0.02 15.4 7.7 0.84 10.2 0.0 4.0 4 0 0 4 4 3 0 AAA domain ADIP PF11559.8 EMG51039.1 - 0.024 14.7 7.1 0.06 13.4 7.1 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Torsin PF06309.11 EMG51039.1 - 0.035 14.2 0.0 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 Torsin MMR_HSR1 PF01926.23 EMG51039.1 - 0.058 13.5 0.1 2.3 8.3 0.1 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase CbiA PF01656.23 EMG51039.1 - 0.059 13.4 0.6 1.3 9.1 0.1 3.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Mitoc_L55 PF09776.9 EMG51039.1 - 0.12 12.2 2.2 0.31 10.8 2.2 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 RuvB_N PF05496.12 EMG51039.1 - 0.13 12.0 3.6 9.9 5.9 0.0 3.4 3 1 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_21 PF13304.6 EMG51039.1 - 0.68 9.7 9.7 4.7 6.9 0.0 4.4 6 0 0 6 6 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4094 PF13334.6 EMG51039.1 - 1.3 9.5 5.1 0.44 11.0 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) EF-hand_4 PF12763.7 EMG51040.1 - 1.8e-24 85.7 0.0 8.4e-12 45.0 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 EMG51040.1 - 2.1e-08 34.5 56.5 6.1e-08 33.0 34.9 11.2 5 2 3 8 8 8 5 Domain of unknown function (DUF1720) WH2 PF02205.20 EMG51040.1 - 0.00026 20.7 0.1 0.00077 19.2 0.1 1.8 1 0 0 1 1 1 1 WH2 motif EF-hand_1 PF00036.32 EMG51040.1 - 0.0013 18.1 0.0 0.19 11.4 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EMG51040.1 - 0.0019 18.6 0.1 0.028 14.9 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EMG51040.1 - 0.0093 15.8 0.7 1.4 8.9 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 EMG51040.1 - 0.061 13.3 0.1 3.1 8.0 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain Phos_pyr_kin PF08543.12 EMG51041.1 - 9.5e-69 231.5 0.0 1.5e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EMG51041.1 - 5.3e-38 130.9 0.2 7.2e-38 130.5 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 EMG51041.1 - 0.0024 17.2 0.0 0.03 13.6 0.0 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase HK PF02110.15 EMG51041.1 - 0.048 13.0 0.2 0.37 10.2 0.2 2.1 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family A_deaminase PF00962.22 EMG51042.1 - 2.1e-120 402.0 0.0 3e-120 401.5 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase SATase_N PF06426.14 EMG51043.1 - 0.046 14.1 0.7 0.53 10.7 0.0 2.9 3 0 0 3 3 3 0 Serine acetyltransferase, N-terminal UTP15_C PF09384.10 EMG51043.1 - 0.076 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 UTP15 C terminal Mem_trans PF03547.18 EMG51044.1 - 4.2e-32 111.0 0.4 9.7e-32 109.8 0.4 1.5 1 1 0 1 1 1 1 Membrane transport protein Rgp1 PF08737.10 EMG51044.1 - 4e-23 82.3 1.0 4e-23 82.3 1.0 3.7 2 2 0 2 2 2 1 Rgp1 Arrestin_C PF02752.22 EMG51044.1 - 3.3e-07 30.8 0.3 3.3e-07 30.8 0.3 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Hamartin PF04388.12 EMG51045.1 - 0.19 10.3 5.5 0.2 10.3 5.5 1.0 1 0 0 1 1 1 0 Hamartin protein ADH_zinc_N_2 PF13602.6 EMG51046.1 - 1.7e-24 87.4 0.0 3.8e-24 86.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMG51046.1 - 5.1e-11 42.7 0.0 1.8e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMG51046.1 - 4.1e-05 23.4 0.0 7.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain THF_DHG_CYH_C PF02882.19 EMG51046.1 - 0.016 14.6 0.1 0.028 13.7 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.21 EMG51046.1 - 0.032 13.5 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EMG51046.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Acetyltransf_1 PF00583.25 EMG51047.1 - 0.033 14.4 0.4 0.66 10.2 0.0 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family LSM PF01423.22 EMG51048.1 - 1.2e-18 66.5 0.5 1.4e-18 66.4 0.5 1.0 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EMG51048.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.2 1 1 0 1 1 1 0 RimP C-terminal SH3 domain tRNA-synt_1e PF01406.19 EMG51049.1 - 0.0045 16.4 1.1 0.0085 15.5 1.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain ENTH PF01417.20 EMG51050.1 - 6.4e-45 152.2 0.1 1e-44 151.5 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EMG51050.1 - 0.0018 17.4 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 EMG51050.1 - 0.38 10.7 21.6 0.37 10.8 16.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5102) SOG2 PF10428.9 EMG51050.1 - 0.56 9.4 23.8 0.94 8.6 23.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SSP160 PF06933.11 EMG51050.1 - 6.7 4.8 17.1 17 3.4 17.1 1.6 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SAC3_GANP PF03399.16 EMG51051.1 - 2.7e-111 371.7 0.2 5.4e-111 370.7 0.2 1.6 1 0 0 1 1 1 1 SAC3/GANP family SAC3 PF12209.8 EMG51051.1 - 1.1e-22 80.0 1.4 1.1e-22 80.0 1.4 2.2 2 0 0 2 2 2 1 Leucine permease transcriptional regulator helical domain Methyltransf_16 PF10294.9 EMG51052.1 - 5.2e-19 68.6 0.2 7.1e-19 68.2 0.2 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Semialdhyde_dhC PF02774.18 EMG51053.1 - 8.4e-43 146.6 0.0 1.3e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EMG51053.1 - 8e-32 110.2 0.0 1.4e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 EMG51053.1 - 0.00089 20.0 0.0 0.0022 18.7 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 EMG51053.1 - 0.00093 19.5 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EMG51053.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SSrecog PF03531.14 EMG51054.1 - 2.8e-30 104.0 0.2 4.4e-28 97.0 0.2 3.1 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EMG51054.1 - 2.5e-28 98.3 0.0 9.9e-27 93.2 0.0 3.1 3 0 0 3 3 3 1 Histone chaperone Rttp106-like POB3_N PF17292.2 EMG51054.1 - 2.6e-24 85.5 0.2 6.4e-23 81.0 0.1 2.7 3 0 0 3 3 3 1 POB3-like N-terminal PH domain CDC45 PF02724.14 EMG51054.1 - 0.031 12.6 9.7 0.045 12.1 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIIC_delta PF12657.7 EMG51055.1 - 2.7e-13 50.2 0.0 6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 EMG51055.1 - 0.032 14.2 0.0 0.23 11.4 0.0 2.4 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Helicase_C_2 PF13307.6 EMG51056.1 - 3.6e-57 193.3 0.1 1.2e-56 191.6 0.1 2.0 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EMG51056.1 - 3.6e-48 163.5 1.5 1.1e-47 161.9 1.5 1.9 1 0 0 1 1 1 1 DEAD_2 Phage_RpbA PF10789.9 EMG51056.1 - 0.0055 16.8 0.5 0.016 15.2 0.5 1.8 1 0 0 1 1 1 1 Phage RNA polymerase binding, RpbA Pinin_SDK_N PF04697.13 EMG51056.1 - 0.063 13.9 0.5 0.14 12.8 0.5 1.5 1 0 0 1 1 1 0 pinin/SDK conserved region UPF0172 PF03665.13 EMG51056.1 - 0.091 12.8 3.3 0.28 11.2 3.3 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Nic96 PF04097.14 EMG51057.1 - 2.3e-195 650.7 4.0 3.1e-195 650.3 4.0 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Spore_III_AB PF09548.10 EMG51057.1 - 0.0036 17.4 0.4 0.016 15.3 0.1 2.2 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) DUF5131 PF07505.11 EMG51057.1 - 0.077 12.4 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) DUF2802 PF10975.8 EMG51057.1 - 0.084 13.0 0.1 0.084 13.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) INCENP_N PF12178.8 EMG51057.1 - 0.17 11.9 0.0 0.59 10.2 0.0 2.0 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal Roughex PF06020.11 EMG51057.1 - 0.41 9.7 4.7 0.69 9.0 4.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein AA_permease_2 PF13520.6 EMG51058.1 - 1.9e-47 162.1 50.4 2.4e-47 161.8 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG51058.1 - 4.3e-23 81.6 45.6 5.9e-23 81.2 45.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.9 EMG51058.1 - 0.11 11.3 0.0 0.11 11.3 0.0 4.0 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) SPC25 PF06703.11 EMG51058.1 - 0.45 10.3 3.7 0.31 10.8 0.5 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SIR2 PF02146.17 EMG51059.1 - 3.2e-62 209.6 0.0 4.5e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EMG51059.1 - 0.0031 17.3 0.1 0.023 14.5 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF592) SSP160 PF06933.11 EMG51059.1 - 0.012 13.9 0.6 0.015 13.5 0.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPP_enzyme_M PF00205.22 EMG51059.1 - 0.09 12.5 0.0 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF4611 PF15387.6 EMG51059.1 - 0.14 12.4 0.2 0.24 11.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Dicty_REP PF05086.12 EMG51059.1 - 0.38 8.7 3.5 0.65 7.9 0.4 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein PALP PF00291.25 EMG51060.1 - 7.4e-57 193.0 0.0 9.1e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YjeF_N PF03853.15 EMG51060.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Fungal_trans PF04082.18 EMG51061.1 - 6.9e-30 104.0 0.1 4.2e-29 101.4 0.0 2.4 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG51061.1 - 1.1e-08 35.0 10.6 1.9e-08 34.3 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMG51062.1 - 1.3e-13 50.6 2.1 1.3e-13 50.6 2.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG51062.1 - 1.8e-06 27.9 10.9 3.9e-06 26.9 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Endonuc-BglII PF09195.11 EMG51062.1 - 0.063 13.1 0.5 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease BglII Glyco_hydro_76 PF03663.14 EMG51063.1 - 9e-153 509.1 24.6 1e-152 508.9 24.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF4690 PF15756.5 EMG51063.1 - 0.0043 17.6 0.1 0.008 16.8 0.1 1.4 1 0 0 1 1 1 1 Small Novel Rich in Cartilage PX PF00787.24 EMG51064.1 - 1.3e-16 60.5 1.9 1.3e-16 60.5 1.9 2.9 3 0 0 3 3 3 1 PX domain YabA PF06156.13 EMG51064.1 - 0.0016 19.0 1.8 0.0016 19.0 1.8 3.2 3 0 0 3 3 3 1 Initiation control protein YabA DUF16 PF01519.16 EMG51064.1 - 0.014 15.9 2.2 0.014 15.9 2.2 3.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 Vps5 PF09325.10 EMG51064.1 - 0.038 13.5 11.9 0.044 13.3 3.7 2.3 2 0 0 2 2 2 0 Vps5 C terminal like DUF2400 PF09674.10 EMG51064.1 - 1.4 8.9 9.1 0.13 12.2 1.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) GAT PF03127.14 EMG51064.1 - 1.8 9.0 8.5 8.4 6.8 0.6 3.6 2 0 0 2 2 2 0 GAT domain DUF1664 PF07889.12 EMG51064.1 - 2.3 8.2 6.0 7.9 6.5 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.10 EMG51064.1 - 7.1 6.5 5.8 4.5 7.1 0.6 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 Lung_7-TM_R PF06814.13 EMG51065.1 - 3.7e-56 190.5 20.2 6.9e-56 189.7 20.2 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor TMEM43 PF07787.12 EMG51065.1 - 0.1 12.0 4.4 0.25 10.7 4.4 1.6 1 0 0 1 1 1 0 Transmembrane protein 43 DUF4234 PF14018.6 EMG51065.1 - 2.8 8.1 6.6 12 6.1 2.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) PCI PF01399.27 EMG51066.1 - 2.3e-10 40.9 1.1 2.3e-10 40.9 1.1 2.2 2 0 0 2 2 2 1 PCI domain Rpn9_C PF18261.1 EMG51066.1 - 1.4e-05 24.6 0.0 3.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Rpn9 C-terminal helix PX PF00787.24 EMG51067.1 - 3.6e-19 68.8 5.3 1.4e-17 63.6 1.0 2.6 2 0 0 2 2 2 2 PX domain BLOC1_2 PF10046.9 EMG51067.1 - 0.23 11.8 6.3 0.54 10.6 0.3 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mannosyl_trans3 PF11051.8 EMG51068.1 - 1.3e-87 293.6 0.0 2.4e-87 292.8 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Acyl_transf_2 PF02273.15 EMG51068.1 - 0.039 13.2 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase ORF6C PF10552.9 EMG51068.1 - 0.05 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 ORF6C domain Hydrolase PF00702.26 EMG51070.1 - 0.0013 19.1 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase 5-nucleotidase PF06189.12 EMG51070.1 - 0.049 12.6 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 5'-nucleotidase PWI PF01480.17 EMG51071.1 - 7.5e-07 29.4 1.1 3.6e-06 27.2 1.1 2.3 1 0 0 1 1 1 1 PWI domain KH_8 PF17903.1 EMG51071.1 - 0.019 15.1 1.2 0.12 12.5 0.2 3.0 2 0 0 2 2 2 0 Krr1 KH1 domain DUF4381 PF14316.6 EMG51071.1 - 0.18 12.0 0.2 0.44 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) NRDE-2 PF08424.10 EMG51072.1 - 0.00051 19.3 11.2 0.024 13.8 1.0 3.9 2 2 2 4 4 4 2 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 EMG51072.1 - 8.7 6.3 17.2 0.2 11.6 3.5 4.5 4 1 1 5 5 5 0 Mad3/BUB1 homology region 1 Nucleoporin_C PF03177.14 EMG51073.1 - 0.041 12.6 0.3 0.085 11.6 0.3 1.5 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal C1_1 PF00130.22 EMG51073.1 - 0.38 10.7 3.2 0.21 11.5 0.2 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UBA PF00627.31 EMG51074.1 - 5.9e-24 83.6 8.6 2.7e-13 49.5 0.5 2.9 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 EMG51074.1 - 1.2e-18 66.6 1.3 4e-18 64.9 0.8 2.2 3 0 0 3 3 3 1 Ubiquitin family XPC-binding PF09280.11 EMG51074.1 - 2e-14 53.0 7.2 3.8e-14 52.2 7.2 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 EMG51074.1 - 8.4e-08 31.9 1.5 2e-07 30.8 1.5 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EMG51074.1 - 0.00026 21.3 0.5 0.00049 20.4 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMG51074.1 - 0.001 19.2 0.1 0.0021 18.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EMG51074.1 - 0.0023 18.5 0.4 0.0059 17.2 0.4 1.7 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain TFIIA PF03153.13 EMG51074.1 - 1.6 8.6 15.4 2.1 8.3 15.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF908 PF06012.12 EMG51074.1 - 2.3 7.5 9.5 0.45 9.9 5.5 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF3306 PF11748.8 EMG51074.1 - 2.7 8.9 12.3 0.13 13.1 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Macoilin PF09726.9 EMG51074.1 - 4 5.9 7.1 5.7 5.4 7.1 1.2 1 0 0 1 1 1 0 Macoilin family DUF3336 PF11815.8 EMG51075.1 - 3.7e-46 156.3 4.8 6.8e-46 155.4 4.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EMG51075.1 - 5e-15 56.2 0.0 1e-14 55.2 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Pept_tRNA_hydro PF01195.19 EMG51076.1 - 5.4e-25 88.3 0.0 6.7e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF5102 PF17104.5 EMG51077.1 - 1.1e-26 94.5 15.1 6.5e-26 92.0 15.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF5102) XTBD PF11952.8 EMG51077.1 - 0.039 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD RRN3 PF05327.11 EMG51077.1 - 0.04 12.5 7.2 0.066 11.8 7.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_I_A49 PF06870.12 EMG51079.1 - 3e-108 362.1 0.8 3.5e-108 361.9 0.8 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DMAP1 PF05499.12 EMG51079.1 - 0.011 15.6 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Sugar_tr PF00083.24 EMG51080.1 - 2.7e-142 474.8 27.0 3.2e-142 474.6 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG51080.1 - 5e-27 94.7 24.6 5e-27 94.7 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMG51080.1 - 0.00019 20.0 3.0 0.00038 19.0 3.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 60KD_IMP PF02096.20 EMG51080.1 - 0.062 13.2 1.9 1.8 8.4 0.0 3.0 2 2 1 3 3 3 0 60Kd inner membrane protein LMF1 PF06762.14 EMG51080.1 - 1.8 7.6 5.8 0.35 9.9 1.7 1.7 2 0 0 2 2 2 0 Lipase maturation factor Ribosomal_L16 PF00252.18 EMG51081.1 - 3.2e-34 117.8 0.3 4e-34 117.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-CSL PF05207.13 EMG51082.1 - 1e-18 66.8 1.8 1.4e-18 66.4 1.8 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EMG51082.1 - 2.1e-14 53.4 0.1 3.4e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Mrr_cat_2 PF13156.6 EMG51082.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease Sugar_tr PF00083.24 EMG51083.1 - 1.4e-148 495.6 33.6 1.6e-148 495.3 33.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMG51083.1 - 2.4e-26 92.5 35.9 1.6e-22 79.9 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_29 PF13551.6 EMG51084.1 - 0.00031 20.7 0.3 0.00072 19.5 0.3 1.7 1 1 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 EMG51084.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 EMG51084.1 - 0.0042 16.6 0.4 0.31 10.6 0.4 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 EMG51084.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 EMG51084.1 - 0.015 15.4 0.2 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 EMG51084.1 - 0.062 13.3 0.1 3 7.8 0.0 2.5 3 0 0 3 3 3 0 HTH domain UCH PF00443.29 EMG51085.1 - 1.8e-54 185.0 0.0 4.7e-54 183.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMG51085.1 - 1.4e-28 100.4 7.4 4.4e-20 72.5 0.2 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CTP_transf_1 PF01148.20 EMG51086.1 - 0.0001 22.2 3.0 0.00015 21.6 3.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family Nop14 PF04147.12 EMG51086.1 - 0.34 9.1 18.3 0.43 8.7 18.3 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EMG51086.1 - 1.3 7.3 12.5 2 6.6 12.5 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EMG51086.1 - 4.8 6.5 16.7 6.1 6.2 16.7 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EMG51086.1 - 5.3 6.3 13.3 6.8 5.9 13.3 1.1 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 EMG51086.1 - 6.5 5.9 10.0 9.8 5.3 10.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Snf7 PF03357.21 EMG51087.1 - 3.8e-22 78.7 29.7 1e-21 77.3 29.7 1.7 1 1 0 1 1 1 1 Snf7 Eno-Rase_FAD_bd PF07055.12 EMG51087.1 - 0.16 12.4 2.6 0.38 11.2 0.6 2.6 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain ZIP4_domain PF18292.1 EMG51087.1 - 0.41 10.5 9.0 0.039 13.9 2.0 2.1 1 1 1 2 2 2 0 Zinc transporter ZIP4 domain DUF948 PF06103.11 EMG51087.1 - 2 8.8 8.3 6.1e+02 0.8 8.2 3.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Pmp3 PF01679.17 EMG51088.1 - 1.7e-12 47.3 11.3 2.6e-12 46.8 11.3 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DNA_pol3_delta2 PF13177.6 EMG51089.1 - 6.1e-12 45.6 0.4 1.3e-11 44.5 0.4 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EMG51089.1 - 4.5e-07 30.4 0.3 1.5e-06 28.7 0.3 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EMG51089.1 - 1e-06 28.8 0.3 3.5e-06 27.1 0.0 2.1 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EMG51089.1 - 0.00064 20.0 2.3 0.005 17.1 0.4 2.8 2 2 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EMG51089.1 - 0.0022 17.7 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EMG51089.1 - 0.0069 16.2 0.4 0.014 15.2 0.2 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 EMG51089.1 - 0.0084 16.5 0.1 0.04 14.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 EMG51089.1 - 0.014 15.5 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PMSR PF01625.21 EMG51090.1 - 6.5e-52 175.8 0.2 7.7e-52 175.5 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase BLM_N PF16202.5 EMG51090.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein ParA PF10609.9 EMG51091.1 - 4.5e-98 327.6 0.5 6.5e-98 327.1 0.5 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EMG51091.1 - 1.3e-10 41.5 0.1 3.3e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMG51091.1 - 1.1e-08 35.3 3.4 8.1e-08 32.4 0.5 2.5 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 EMG51091.1 - 1.2e-08 34.7 0.6 0.0021 17.5 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EMG51091.1 - 3.5e-07 29.8 0.0 5.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EMG51091.1 - 0.00018 20.8 0.8 0.00053 19.3 0.6 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EMG51091.1 - 0.032 13.7 0.5 0.067 12.7 0.2 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ VirC1 PF07015.11 EMG51091.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein DUF1610 PF07754.11 EMG51091.1 - 0.12 12.4 0.2 0.31 11.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) PhnA_Zn_Ribbon PF08274.12 EMG51091.1 - 0.17 11.8 0.3 0.39 10.7 0.3 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon HEXIM PF15313.6 EMG51091.1 - 0.21 11.8 7.7 0.086 13.0 4.0 2.0 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein MnmE_helical PF12631.7 EMG51092.1 - 1.2e-40 139.9 0.1 2.8e-40 138.7 0.1 1.6 1 1 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EMG51092.1 - 1.2e-32 112.7 0.0 4.1e-32 110.9 0.0 1.9 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EMG51092.1 - 1.3e-18 67.2 2.9 1.3e-18 67.1 0.4 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 EMG51092.1 - 2.3e-07 30.4 1.3 0.00018 21.0 0.4 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EMG51092.1 - 3.8e-07 30.2 1.8 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EMG51092.1 - 9.8e-07 28.4 0.5 1.6e-06 27.7 0.5 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EMG51092.1 - 7.8e-05 22.3 0.8 0.00034 20.2 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EMG51092.1 - 0.00041 20.5 1.3 0.0024 17.9 0.1 2.7 2 2 0 2 2 2 1 Dynamin family Roc PF08477.13 EMG51092.1 - 0.0027 17.9 0.4 1.9 8.7 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase RNA_binding PF01877.17 EMG51092.1 - 0.0048 17.2 0.7 0.0048 17.2 0.7 2.8 3 0 0 3 3 2 1 RNA binding AAA_22 PF13401.6 EMG51092.1 - 0.017 15.4 0.3 0.084 13.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain Gtr1_RagA PF04670.12 EMG51092.1 - 0.018 14.4 1.1 0.19 11.0 0.1 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region eIF3_subunit PF08597.10 EMG51092.1 - 0.058 13.3 1.9 3.9 7.3 0.2 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit AAA PF00004.29 EMG51092.1 - 0.084 13.3 2.0 0.85 10.0 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SWIRM PF04433.17 EMG51092.1 - 0.14 12.5 0.7 29 5.1 0.0 3.1 2 2 0 2 2 2 0 SWIRM domain TBCA PF02970.16 EMG51092.1 - 1 9.7 5.3 18 5.7 0.1 2.6 2 1 0 2 2 2 0 Tubulin binding cofactor A Syntaxin_2 PF14523.6 EMG51092.1 - 1.5 9.2 7.6 8.6 6.8 0.6 3.4 3 1 1 4 4 4 0 Syntaxin-like protein DUF2536 PF10750.9 EMG51092.1 - 1.9 8.5 4.8 28 4.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) ABC_tran PF00005.27 EMG51092.1 - 2.7 8.5 10.3 0.088 13.3 1.7 2.6 2 1 1 3 3 3 0 ABC transporter Lebercilin PF15619.6 EMG51092.1 - 3.3 7.3 7.3 0.48 10.0 1.1 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Bromodomain PF00439.25 EMG51093.1 - 2.6e-31 107.5 3.3 2.1e-16 59.7 0.0 3.0 3 0 0 3 3 3 2 Bromodomain SbsC_C PF18058.1 EMG51093.1 - 0.14 12.3 1.3 8 6.7 0.3 2.7 2 0 0 2 2 2 0 SbsC C-terminal domain tRNA-synt_2d PF01409.20 EMG51094.1 - 1.2e-45 156.0 0.2 6.9e-24 84.7 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EMG51094.1 - 9.6e-29 99.7 0.0 2.4e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Flavodoxin_1 PF00258.25 EMG51094.1 - 2.8e-28 98.9 0.0 3.8e-27 95.3 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 EMG51094.1 - 1.4e-17 64.0 0.0 2.3e-11 43.7 0.0 2.4 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.21 EMG51094.1 - 1.1e-13 51.7 0.0 3.3e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 EMG51094.1 - 0.0052 16.5 0.1 0.05 13.3 0.0 2.3 2 1 0 2 2 2 1 Flavodoxin domain Oxidored_FMN PF00724.20 EMG51095.1 - 1.9e-84 283.9 0.0 2.2e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 EMG51095.1 - 0.11 11.9 0.0 0.64 9.4 0.0 2.0 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel LAMTOR PF15454.6 EMG51096.1 - 6.5e-12 45.9 8.2 6.5e-12 45.9 8.2 1.7 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator GFO_IDH_MocA PF01408.22 EMG51097.1 - 4.6e-19 69.4 0.1 8.9e-19 68.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EMG51097.1 - 0.0039 17.8 0.0 0.0075 16.9 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OpuAC PF04069.12 EMG51097.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Sacchrp_dh_NADP PF03435.18 EMG51097.1 - 0.032 14.5 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF4767 PF15983.5 EMG51097.1 - 0.042 14.1 0.7 0.075 13.3 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4767) F420_oxidored PF03807.17 EMG51097.1 - 0.13 12.9 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Zip PF02535.22 EMG51098.1 - 0.98 8.6 4.4 1.6 7.8 4.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 EMG51098.1 - 1.9 7.8 12.9 3.8 6.9 12.9 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CNDH2_M PF16869.5 EMG51098.1 - 3.7 8.3 9.8 1.9 9.2 6.6 2.1 2 0 0 2 2 2 0 PF16858 Abhydrolase_1 PF00561.20 EMG51099.1 - 5.1e-27 95.1 0.5 6.7e-27 94.7 0.5 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EMG51099.1 - 1.1e-19 69.8 0.1 2.9e-19 68.4 0.1 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EMG51099.1 - 1.5e-09 37.5 0.0 1.3e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EMG51099.1 - 0.0079 16.0 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 EMG51099.1 - 0.019 14.6 0.1 5.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Nha1_C PF08619.10 EMG51099.1 - 0.088 12.0 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus TMCCDC2 PF15844.5 EMG51100.1 - 2 8.3 8.9 0.041 13.8 2.1 1.7 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 TMEM52 PF14979.6 EMG51100.1 - 2.2 8.2 3.4 3 7.7 0.5 2.4 2 1 0 2 2 2 0 Transmembrane 52 DUF3522 PF12036.8 EMG51102.1 - 0.026 14.8 0.2 0.036 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) DUF4589 PF15252.6 EMG51102.1 - 0.35 10.8 3.1 0.38 10.7 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) AMMECR1 PF01871.17 EMG51103.1 - 1.5e-38 132.1 0.0 1.8e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Thiolase_N PF00108.23 EMG51104.1 - 1.7e-72 244.0 0.1 2.5e-72 243.4 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMG51104.1 - 2.2e-38 130.7 0.3 1.3e-37 128.1 0.0 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMG51104.1 - 0.006 16.2 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain zf-C2H2_2 PF12756.7 EMG51105.1 - 0.021 15.2 0.9 0.044 14.1 0.9 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EMG51105.1 - 1.1 9.9 7.0 1.6 9.3 0.8 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type CRC_subunit PF08624.10 EMG51106.1 - 2.4e-49 167.2 0.1 4.5e-49 166.4 0.1 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF3138 PF11336.8 EMG51106.1 - 0.15 10.7 0.3 0.2 10.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CDC27 PF09507.10 EMG51106.1 - 1.1 8.6 20.6 1.7 7.9 20.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C2H2 PF00096.26 EMG51107.1 - 1.2e-05 25.4 4.6 0.054 14.0 0.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 EMG51107.1 - 0.0089 16.3 1.5 0.03 14.6 1.5 1.9 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 EMG51107.1 - 0.11 12.6 1.5 0.18 11.9 0.2 2.0 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 EMG51107.1 - 0.25 12.3 0.3 0.25 12.3 0.3 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMG51107.1 - 0.81 10.2 4.3 2.2 8.8 1.5 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Peptidase_M41 PF01434.18 EMG51108.1 - 1.2e-65 220.9 0.0 2.5e-65 219.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EMG51108.1 - 3.5e-43 147.2 0.0 4.2e-42 143.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMG51108.1 - 9.9e-13 47.7 0.1 3e-12 46.2 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EMG51108.1 - 1.7e-11 44.4 1.2 4e-11 43.2 1.2 1.7 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.13 EMG51108.1 - 0.0032 16.7 0.0 0.0094 15.2 0.0 1.8 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EMG51108.1 - 0.0036 17.6 0.5 0.86 9.9 0.1 3.3 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EMG51108.1 - 0.0048 16.7 0.0 0.018 14.8 0.0 1.9 1 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EMG51108.1 - 0.0051 17.3 0.6 0.8 10.3 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_2 PF07724.14 EMG51108.1 - 0.0054 16.9 0.5 0.032 14.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EMG51108.1 - 0.0063 16.9 0.4 0.025 15.0 0.0 2.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EMG51108.1 - 0.013 15.2 0.2 0.062 13.0 0.0 2.2 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 EMG51108.1 - 0.014 15.4 0.5 0.097 12.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EMG51108.1 - 0.13 12.3 0.4 0.47 10.5 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EMG51108.1 - 0.13 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMG51108.1 - 0.47 10.8 4.9 0.12 12.8 0.2 2.4 3 1 0 3 3 1 0 AAA ATPase domain Adap_comp_sub PF00928.21 EMG51109.1 - 3.8e-53 180.5 4.0 9.2e-53 179.3 4.0 1.7 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Arc_PepC_II PF06847.11 EMG51109.1 - 0.69 10.5 3.2 5.8 7.5 0.0 3.4 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II Ferlin_C PF16165.5 EMG51109.1 - 1.1 9.2 4.5 3.5 7.5 4.5 1.8 1 0 0 1 1 1 0 Ferlin C-terminus MFMR_assoc PF16596.5 EMG51109.1 - 1.2 9.5 7.5 2.8 8.4 7.5 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR CPSF100_C PF13299.6 EMG51109.1 - 3 8.0 10.2 0.61 10.2 2.3 2.8 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 EMG51109.1 - 3.3 5.9 13.5 0.16 10.2 1.6 2.2 2 0 0 2 2 2 0 CDC45-like protein GEMIN8 PF15348.6 EMG51109.1 - 5.4 7.3 9.8 5.1 7.3 1.0 2.3 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 ETRAMP PF09716.10 EMG51109.1 - 8.2 6.6 10.1 0.17 12.0 1.1 2.7 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Nramp PF01566.18 EMG51110.1 - 4.4e-89 299.0 17.1 2.8e-51 174.6 4.0 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Nfu_N PF08712.11 EMG51112.1 - 6.3e-27 93.5 1.2 1.4e-26 92.3 0.1 2.2 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EMG51112.1 - 1.1e-26 92.7 0.1 1.7e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain ATP-synt_J PF04911.12 EMG51112.1 - 9e-21 73.2 0.6 1.6e-20 72.4 0.6 1.4 1 0 0 1 1 1 1 ATP synthase j chain YojJ PF10372.9 EMG51112.1 - 0.002 18.2 0.9 0.0043 17.1 0.9 1.5 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus RhoGAP PF00620.27 EMG51112.1 - 0.03 14.2 0.3 0.15 11.9 0.1 2.2 3 0 0 3 3 3 0 RhoGAP domain Methyltransf_16 PF10294.9 EMG51113.1 - 4.7e-25 88.3 0.3 7.1e-25 87.7 0.3 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EMG51113.1 - 1.8e-07 30.9 0.0 3.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EMG51113.1 - 7.5e-07 29.8 0.0 1.3e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMG51113.1 - 5.4e-05 23.9 0.1 0.00011 22.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMG51113.1 - 0.00032 20.6 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EMG51113.1 - 0.00043 20.3 0.0 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EMG51113.1 - 0.00046 19.3 0.1 0.00078 18.5 0.1 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 EMG51113.1 - 0.00087 18.8 0.1 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EMG51113.1 - 0.0015 18.3 0.2 0.0027 17.5 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain FAM86 PF14904.6 EMG51113.1 - 0.0037 17.3 0.2 0.0077 16.3 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function Methyltransf_4 PF02390.17 EMG51113.1 - 0.0038 16.7 0.2 0.0064 16.0 0.2 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 EMG51113.1 - 0.0066 17.1 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 EMG51113.1 - 0.067 12.3 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Allantoicase PF03561.15 EMG51114.1 - 3e-93 309.4 0.2 5.6e-47 159.3 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat DUF5017 PF16409.5 EMG51114.1 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5017) F5_F8_type_C PF00754.25 EMG51114.1 - 0.016 15.3 0.4 0.066 13.3 0.0 2.2 2 0 0 2 2 2 0 F5/8 type C domain ArAE_2_N PF10337.9 EMG51115.1 - 1.1e-133 446.7 3.8 1.1e-133 446.7 3.8 2.9 3 0 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EMG51115.1 - 1.8e-68 230.8 0.5 6.7e-68 228.9 0.2 2.2 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EMG51115.1 - 7.4e-08 32.6 14.9 7.4e-08 32.6 14.9 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 EMG51116.1 - 4.9e-147 490.8 5.6 4.9e-147 490.8 5.6 1.8 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EMG51116.1 - 2.6e-77 259.8 0.2 1.3e-75 254.1 0.1 2.5 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EMG51116.1 - 6.8e-07 29.5 12.6 6.8e-07 29.5 12.6 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like Sod_Cu PF00080.20 EMG51117.1 - 3.4e-17 62.9 0.4 4.6e-17 62.5 0.4 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Fmp27 PF10344.9 EMG51117.1 - 0.0098 14.0 0.4 0.013 13.7 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 RAP1 PF07218.11 EMG51117.1 - 0.18 10.0 16.1 0.23 9.7 16.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 EMG51117.1 - 0.73 8.3 8.4 0.84 8.1 8.4 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EMG51117.1 - 8.8 5.0 8.4 12 4.7 8.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF5423 PF17461.2 EMG51117.1 - 9 5.0 14.7 15 4.3 14.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Herpes_capsid PF06112.11 EMG51117.1 - 9.5 6.3 19.4 20 5.2 19.4 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Exo_endo_phos PF03372.23 EMG51118.1 - 3.8e-07 29.9 0.0 6.3e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.23 EMG51119.1 - 2.7e-12 46.7 0.1 5e-12 45.8 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EMG51119.1 - 0.00025 20.9 0.1 0.00069 19.4 0.1 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase AA_permease_2 PF13520.6 EMG51120.1 - 1.5e-48 165.7 55.5 1.8e-48 165.4 55.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG51120.1 - 5.8e-23 81.2 47.9 7.7e-23 80.8 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.9 EMG51120.1 - 0.076 11.8 0.0 0.076 11.8 0.0 3.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Insulin_TMD PF17870.1 EMG51120.1 - 2 8.6 6.4 0.42 10.7 0.2 3.1 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment MatE PF01554.18 EMG51121.1 - 9.2e-60 200.9 37.9 1.1e-35 122.6 7.1 2.8 3 0 0 3 3 3 2 MatE Glyco_hydro_76 PF03663.14 EMG51122.1 - 1e-145 485.9 17.8 1.3e-145 485.6 17.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF4690 PF15756.5 EMG51122.1 - 0.12 13.0 0.1 0.22 12.1 0.1 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage HAD_2 PF13419.6 EMG51123.1 - 1.8e-07 31.4 0.4 1.4e-05 25.3 0.4 2.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMG51123.1 - 8e-07 29.0 0.0 2.3e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EMG51123.1 - 1.3e-05 25.6 0.0 2.9e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3085 PF11284.8 EMG51123.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) Fungal_trans_2 PF11951.8 EMG51124.1 - 3.2e-48 164.5 8.2 1.2e-47 162.5 8.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMG51124.1 - 2.6e-07 30.7 9.2 2.6e-07 30.7 9.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 EMG51125.1 - 3.2e-46 158.0 57.1 3.7e-46 157.8 57.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG51125.1 - 4.9e-18 65.0 46.5 6.1e-18 64.7 46.5 1.1 1 0 0 1 1 1 1 Amino acid permease SfLAP PF11139.8 EMG51125.1 - 0.0045 16.4 0.7 0.0045 16.4 0.7 2.4 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein AA_permease_2 PF13520.6 EMG51126.1 - 2e-43 148.8 58.7 2.5e-43 148.5 58.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMG51126.1 - 2.1e-15 56.3 49.2 2.8e-15 55.9 49.2 1.1 1 0 0 1 1 1 1 Amino acid permease CBFD_NFYB_HMF PF00808.23 EMG51128.1 - 5.6e-09 36.2 0.2 1.1e-08 35.2 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMG51128.1 - 4.3e-07 30.3 0.1 4.3e-07 30.3 0.1 3.0 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EMG51128.1 - 8e-05 22.7 0.4 0.00014 21.9 0.4 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TrmB PF01978.19 EMG51128.1 - 0.089 12.7 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB TAFII28 PF04719.14 EMG51128.1 - 0.093 12.8 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Rit1_C PF17184.4 EMG51128.1 - 4.5 6.6 10.4 0.052 13.0 2.7 1.6 2 0 0 2 2 2 0 Rit1 N-terminal domain Transposase_24 PF03004.14 EMG51129.1 - 0.056 13.5 0.2 0.068 13.3 0.2 1.1 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Spem1 PF15670.5 EMG51129.1 - 0.056 13.0 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 HA2 PF04408.23 EMG51130.1 - 7.3e-27 93.8 0.0 7.3e-27 93.8 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMG51130.1 - 8.7e-12 45.4 0.0 8.4e-11 42.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMG51130.1 - 2.1e-09 37.6 0.0 1.5e-08 34.8 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EMG51130.1 - 4.3e-07 29.9 0.0 9.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMG51130.1 - 0.0002 21.6 0.1 0.00091 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EMG51130.1 - 0.12 11.4 0.0 0.3 10.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein V-set PF07686.17 EMG51130.1 - 0.37 11.0 2.0 8.7 6.6 0.1 3.5 3 0 0 3 3 3 0 Immunoglobulin V-set domain 2Fe-2S_thioredx PF01257.19 EMG51131.1 - 1.9e-59 199.7 0.2 2.3e-59 199.4 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Nefa_Nip30_N PF10187.9 EMG51132.1 - 0.03 14.7 2.6 0.033 14.6 2.6 1.1 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 WD40 PF00400.32 EMG51134.1 - 6.6e-23 80.6 15.0 0.0012 19.6 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMG51134.1 - 5.6e-18 65.0 8.0 8.7e-08 32.4 0.5 4.5 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMG51134.1 - 1.8e-06 28.0 1.8 0.22 11.4 0.1 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EMG51134.1 - 0.0058 15.6 0.0 0.052 12.5 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein MOZ_SAS PF01853.18 EMG51135.1 - 7.2e-53 178.9 0.6 1.1e-52 178.3 0.6 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EMG51135.1 - 1.1e-09 37.8 6.0 4.1e-06 26.3 2.7 2.7 2 0 0 2 2 2 2 MYST family zinc finger domain zf-C2H2 PF00096.26 EMG51135.1 - 0.031 14.8 0.4 0.079 13.4 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Acetyltransf_7 PF13508.7 EMG51135.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SNF2_N PF00176.23 EMG51136.1 - 3.2e-71 239.9 0.2 4.9e-71 239.3 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMG51136.1 - 4.1e-13 49.6 0.0 1.1e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 EMG51136.1 - 3e-11 43.1 0.0 6.3e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain ResIII PF04851.15 EMG51136.1 - 2e-07 31.2 0.0 9.8e-07 28.9 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 EMG51136.1 - 6.8e-07 29.5 9.4 1.6e-06 28.3 9.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EMG51136.1 - 4.2e-06 26.5 10.7 8.8e-06 25.5 10.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMG51136.1 - 4.3e-06 26.5 7.0 7.5e-06 25.7 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMG51136.1 - 7.9e-06 25.7 8.6 1.6e-05 24.7 8.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMG51136.1 - 4.2e-05 23.5 7.7 9.1e-05 22.4 7.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EMG51136.1 - 0.0011 18.8 10.5 0.0025 17.6 10.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMG51136.1 - 0.0057 16.8 9.0 0.014 15.5 9.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EMG51136.1 - 0.036 14.1 1.9 0.2 11.7 1.9 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EMG51136.1 - 0.044 13.6 4.7 0.11 12.4 4.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EMG51136.1 - 0.088 12.7 8.0 0.17 11.8 8.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf_Rg PF17915.1 EMG51136.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Reverse gyrase zinc finger zf-RING_11 PF17123.5 EMG51136.1 - 0.26 11.1 7.3 0.54 10.1 7.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 EMG51136.1 - 1.1 9.6 11.1 0.14 12.5 6.4 2.0 2 0 0 2 2 1 0 RING-H2 zinc finger domain Creatinase_N_2 PF16189.5 EMG51137.1 - 9.6e-46 155.8 0.2 8.2e-45 152.8 0.0 2.5 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EMG51137.1 - 7e-37 127.1 0.0 1.4e-36 126.1 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EMG51137.1 - 3.7e-23 81.3 0.8 8.9e-23 80.1 0.4 2.0 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EMG51137.1 - 8.3e-14 52.4 0.0 1.9e-11 44.7 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Herpes_UL92 PF03048.14 EMG51138.1 - 0.00023 21.0 1.2 0.11 12.3 0.1 3.0 2 0 0 2 2 2 2 UL92 family Importin_rep PF18773.1 EMG51138.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 Importin 13 repeat Rep_fac-A_C PF08646.10 EMG51139.1 - 2.4e-50 170.1 8.1 7.7e-50 168.4 1.3 3.0 3 1 1 4 4 4 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EMG51139.1 - 8.7e-33 112.2 0.6 9.2e-32 108.9 0.1 2.6 3 0 0 3 3 3 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 EMG51139.1 - 6.8e-15 54.8 2.6 1.3e-07 31.5 0.0 4.5 3 1 0 4 4 4 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 EMG51139.1 - 4e-13 49.3 0.2 8.9e-13 48.1 0.2 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain CDC24_OB3 PF17244.2 EMG51139.1 - 3e-05 23.8 0.2 0.056 13.1 0.0 2.8 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 EMG51139.1 - 0.00016 21.9 0.2 0.00055 20.2 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF223 TPP1 PF10341.9 EMG51139.1 - 0.025 14.6 0.5 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD MCM_bind PF09739.9 EMG51139.1 - 0.042 12.3 0.1 0.056 11.9 0.1 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Cys_Met_Meta_PP PF01053.20 EMG51140.1 - 3.4e-137 457.0 0.0 4e-137 456.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EMG51140.1 - 3.3e-06 26.7 0.0 2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EMG51140.1 - 7e-06 24.8 0.0 6.4e-05 21.6 0.0 2.0 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 EMG51140.1 - 2.5e-05 23.6 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMG51140.1 - 0.0024 16.9 0.2 0.0083 15.1 0.1 1.9 2 1 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMG51141.1 - 2e-06 27.2 0.0 2.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1406 PF07190.11 EMG51141.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1406) DegT_DnrJ_EryC1 PF01041.17 EMG51141.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family HABP4_PAI-RBP1 PF04774.15 EMG51142.1 - 0.0058 17.5 2.6 0.0058 17.5 2.6 1.3 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family CTP_transf_like PF01467.26 EMG51143.1 - 5.9e-33 114.1 0.0 3.2e-19 69.5 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EMG51143.1 - 0.00031 20.7 0.1 0.019 14.9 0.1 2.6 3 0 0 3 3 3 1 FAD synthetase DUF4112 PF13430.6 EMG51144.1 - 4.4e-25 88.0 0.4 7.5e-25 87.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) zf-CCCH PF00642.24 EMG51144.1 - 9e-10 38.2 1.9 2e-09 37.1 1.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EMG51144.1 - 1.7e-06 27.9 4.9 4.8e-06 26.4 4.9 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 EMG51144.1 - 6.1e-06 26.0 5.8 1.7e-05 24.6 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMG51144.1 - 1.1e-05 25.2 5.4 2.3e-05 24.2 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMG51144.1 - 1.2e-05 25.2 4.9 3.1e-05 23.9 4.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EMG51144.1 - 1.9e-05 24.4 4.5 4.4e-05 23.3 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMG51144.1 - 0.00017 21.8 3.8 0.00038 20.7 3.8 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EMG51144.1 - 0.0016 18.2 3.6 0.0038 17.1 3.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 EMG51144.1 - 0.0021 17.8 1.6 0.0021 17.8 1.6 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 EMG51144.1 - 0.0054 16.9 5.4 0.013 15.7 5.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EMG51144.1 - 0.0056 16.6 6.5 0.0056 16.6 6.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain DUF104 PF01954.16 EMG51144.1 - 0.085 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF104 zf-RING_10 PF16685.5 EMG51144.1 - 0.087 13.0 3.8 0.24 11.6 3.8 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF4407 PF14362.6 EMG51144.1 - 0.17 11.2 2.2 0.39 10.0 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ImpA_N PF06812.12 EMG51144.1 - 0.51 10.5 5.2 0.67 10.1 0.0 2.6 2 1 0 2 2 2 0 ImpA, N-terminal, type VI secretion system zf-CCCH_2 PF14608.6 EMG51144.1 - 2.3 8.8 6.2 0.37 11.3 2.0 1.9 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger HSCB_C PF07743.13 EMG51145.1 - 2.4e-17 63.2 4.0 3.8e-17 62.5 4.0 1.3 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EMG51145.1 - 3.8e-05 23.7 1.8 7.5e-05 22.8 0.2 2.3 2 1 0 2 2 2 1 DnaJ domain Cnl2_NKP2 PF09447.10 EMG51145.1 - 0.019 15.1 0.1 0.019 15.1 0.1 2.2 3 0 0 3 3 3 0 Cnl2/NKP2 family protein CK_II_beta PF01214.18 EMG51146.1 - 7.2e-67 224.7 0.5 1.8e-66 223.4 0.5 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Secretin_N_2 PF07655.13 EMG51146.1 - 0.14 12.7 6.8 0.24 12.0 6.8 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Zip PF02535.22 EMG51146.1 - 0.23 10.6 0.3 12 5.0 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter RXT2_N PF08595.11 EMG51146.1 - 2.2 8.3 14.5 6.2 6.8 7.6 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal BUD22 PF09073.10 EMG51146.1 - 6.8 5.9 14.1 6.2 6.0 7.7 2.0 2 0 0 2 2 2 0 BUD22 Pox_Ag35 PF03286.14 EMG51146.1 - 9.2 6.0 14.2 1.3 8.8 4.0 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein WD40 PF00400.32 EMG51147.1 - 3.6e-33 113.0 16.5 3.4e-09 37.2 0.1 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Hira PF07569.11 EMG51147.1 - 2.6e-19 69.8 0.0 6e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 EMG51147.1 - 1.9e-17 63.3 0.1 0.031 14.6 0.0 7.0 5 1 3 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EMG51147.1 - 1.2e-09 37.7 2.2 3e-09 36.5 2.2 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EMG51147.1 - 5.9e-08 32.4 0.2 5.1 7.1 0.0 4.9 4 0 0 4 4 4 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EMG51147.1 - 0.00027 20.0 0.1 22 3.9 0.0 5.5 2 1 4 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EMG51147.1 - 0.011 15.1 0.0 3.2 7.0 0.0 3.0 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal NigD_N PF12667.7 EMG51147.1 - 0.13 12.4 0.2 0.51 10.5 0.2 2.0 1 0 0 1 1 1 0 NigD-like N-terminal OB domain Reg_prop PF07494.11 EMG51147.1 - 0.17 12.2 1.1 54 4.5 0.1 3.6 3 0 0 3 3 3 0 Two component regulator propeller Aminotran_1_2 PF00155.21 EMG51148.1 - 7.6e-05 22.0 0.0 9.5e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Candida_maltosa_Xu316-Cmaltosa_v01/GCA_000344705.1_Cmaltosa_v01_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Candida_maltosa_Xu316-Cmaltosa_v01/GCA_000344705.1_Cmaltosa_v01_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Candida_maltosa_Xu316-Cmaltosa_v01/GCA_000344705.1_Cmaltosa_v01_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Candida_maltosa_Xu316-Cmaltosa_v01/GCA_000344705.1_Cmaltosa_v01_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 15:39:02 2019 # [ok]